data_8UYC
# 
_entry.id   8UYC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UYC         pdb_00008uyc 10.2210/pdb8uyc/pdb 
WWPDB D_1000277586 ?            ?                   
EMDB  EMD-42799    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UYC 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB MgtA_dimer_C2                                                              EMD-42794 'other EM volume'      
EMDB MgtA_dimer_C1                                                              EMD-42795 'other EM volume'      
EMDB MgtA_monomer                                                               EMD-42796 'other EM volume'      
EMDB MgtA_dimer-ATP                                                             EMD-42797 'other EM volume'      
EMDB MgtA_dimer-ATPyS                                                           EMD-42798 'other EM volume'      
EMDB 'Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ADP' EMD-42799 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 doreen.matthies@nih.gov      Doreen    Matthies ? 'principal investigator/group leader' 0000-0001-9221-4484 
3 storzg@mail.nih.gov          Gisela    Storz    ? 'principal investigator/group leader' 0000-0001-6698-1241 
4 alexander.sodt@nih.gov       Alexander Sodt     ? 'principal investigator/group leader' 0000-0002-5570-8212 
5 julian.langer@biophys.mpg.de Julian    Langer   D 'principal investigator/group leader' 0000-0002-5190-577X 
6 aravind@ncbi.nlm.nih.gov     Aravind   Iyer     ? 'principal investigator/group leader' 0000-0003-0771-253X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zeinert, R.'             1  0000-0003-3542-0227 
'Zhou, F.'                2  0000-0001-6657-7433 
'Cavalcanti Franco, P.H.' 3  0000-0002-3148-2319 
'Zoeller, J.'             4  0000-0002-7989-0768 
'Lessen, H.'              5  0000-0002-8764-8859 
'Iyer, A.'                6  0000-0003-0771-253X 
'Langer, J.D.'            7  0000-0002-5190-577X 
'Sodt, A.J.'              8  0000-0002-5570-8212 
'Storz, G.'               9  0000-0001-6698-1241 
'Matthies, D.'            10 0000-0001-9221-4484 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zeinert, R.'             1  0000-0003-3542-0227 
primary 'Zhou, F.'                2  0000-0001-6657-7433 
primary 'Cavalcanti Franco, P.H.' 3  0000-0002-3148-2319 
primary 'Zoeller, J.'             4  0000-0002-7989-0768 
primary 'Lessen, H.'              5  0000-0002-8764-8859 
primary 'Iyer, A.'                6  0000-0003-0771-253X 
primary 'Langer, J.D.'            7  0000-0002-5190-577X 
primary 'Sodt, A.J.'              8  0000-0002-5570-8212 
primary 'Storz, G.'               9  0000-0001-6698-1241 
primary 'Matthies, D.'            10 0000-0001-9221-4484 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Magnesium-transporting ATPase, P-type 1' 100393.062 2 ? ? ? ? 
2 non-polymer syn 'MAGNESIUM ION'                           24.305     6 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'MAGNESIUM ION' 
_pdbx_entity_nonpoly.comp_id     MG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PHE n 
1 3   LYS n 
1 4   GLU n 
1 5   ILE n 
1 6   PHE n 
1 7   THR n 
1 8   ARG n 
1 9   LEU n 
1 10  ILE n 
1 11  ARG n 
1 12  HIS n 
1 13  LEU n 
1 14  PRO n 
1 15  SER n 
1 16  ARG n 
1 17  LEU n 
1 18  VAL n 
1 19  HIS n 
1 20  ARG n 
1 21  ASP n 
1 22  PRO n 
1 23  LEU n 
1 24  PRO n 
1 25  GLY n 
1 26  ALA n 
1 27  GLN n 
1 28  GLN n 
1 29  THR n 
1 30  VAL n 
1 31  ASN n 
1 32  THR n 
1 33  VAL n 
1 34  VAL n 
1 35  PRO n 
1 36  PRO n 
1 37  SER n 
1 38  LEU n 
1 39  SER n 
1 40  ALA n 
1 41  HIS n 
1 42  CYS n 
1 43  LEU n 
1 44  LYS n 
1 45  MET n 
1 46  ALA n 
1 47  VAL n 
1 48  MET n 
1 49  PRO n 
1 50  GLU n 
1 51  GLU n 
1 52  GLU n 
1 53  LEU n 
1 54  TRP n 
1 55  LYS n 
1 56  THR n 
1 57  PHE n 
1 58  ASP n 
1 59  THR n 
1 60  HIS n 
1 61  PRO n 
1 62  GLU n 
1 63  GLY n 
1 64  LEU n 
1 65  ASN n 
1 66  GLN n 
1 67  ALA n 
1 68  GLU n 
1 69  VAL n 
1 70  GLU n 
1 71  SER n 
1 72  ALA n 
1 73  ARG n 
1 74  GLU n 
1 75  GLN n 
1 76  HIS n 
1 77  GLY n 
1 78  GLU n 
1 79  ASN n 
1 80  LYS n 
1 81  LEU n 
1 82  PRO n 
1 83  ALA n 
1 84  GLN n 
1 85  GLN n 
1 86  PRO n 
1 87  SER n 
1 88  PRO n 
1 89  TRP n 
1 90  TRP n 
1 91  VAL n 
1 92  HIS n 
1 93  LEU n 
1 94  TRP n 
1 95  VAL n 
1 96  CYS n 
1 97  TYR n 
1 98  ARG n 
1 99  ASN n 
1 100 PRO n 
1 101 PHE n 
1 102 ASN n 
1 103 ILE n 
1 104 LEU n 
1 105 LEU n 
1 106 THR n 
1 107 ILE n 
1 108 LEU n 
1 109 GLY n 
1 110 ALA n 
1 111 ILE n 
1 112 SER n 
1 113 TYR n 
1 114 ALA n 
1 115 THR n 
1 116 GLU n 
1 117 ASP n 
1 118 LEU n 
1 119 PHE n 
1 120 ALA n 
1 121 ALA n 
1 122 GLY n 
1 123 VAL n 
1 124 ILE n 
1 125 ALA n 
1 126 LEU n 
1 127 MET n 
1 128 VAL n 
1 129 ALA n 
1 130 ILE n 
1 131 SER n 
1 132 THR n 
1 133 LEU n 
1 134 LEU n 
1 135 ASN n 
1 136 PHE n 
1 137 ILE n 
1 138 GLN n 
1 139 GLU n 
1 140 ALA n 
1 141 ARG n 
1 142 SER n 
1 143 THR n 
1 144 LYS n 
1 145 ALA n 
1 146 ALA n 
1 147 ASP n 
1 148 ALA n 
1 149 LEU n 
1 150 LYS n 
1 151 ALA n 
1 152 MET n 
1 153 VAL n 
1 154 SER n 
1 155 ASN n 
1 156 THR n 
1 157 ALA n 
1 158 THR n 
1 159 VAL n 
1 160 LEU n 
1 161 ARG n 
1 162 VAL n 
1 163 ILE n 
1 164 ASN n 
1 165 ASP n 
1 166 LYS n 
1 167 GLY n 
1 168 GLU n 
1 169 ASN n 
1 170 GLY n 
1 171 TRP n 
1 172 LEU n 
1 173 GLU n 
1 174 ILE n 
1 175 PRO n 
1 176 ILE n 
1 177 ASP n 
1 178 GLN n 
1 179 LEU n 
1 180 VAL n 
1 181 PRO n 
1 182 GLY n 
1 183 ASP n 
1 184 ILE n 
1 185 ILE n 
1 186 LYS n 
1 187 LEU n 
1 188 ALA n 
1 189 ALA n 
1 190 GLY n 
1 191 ASP n 
1 192 MET n 
1 193 ILE n 
1 194 PRO n 
1 195 ALA n 
1 196 ASP n 
1 197 LEU n 
1 198 ARG n 
1 199 ILE n 
1 200 LEU n 
1 201 GLN n 
1 202 ALA n 
1 203 ARG n 
1 204 ASP n 
1 205 LEU n 
1 206 PHE n 
1 207 VAL n 
1 208 ALA n 
1 209 GLN n 
1 210 ALA n 
1 211 SER n 
1 212 LEU n 
1 213 THR n 
1 214 GLY n 
1 215 GLU n 
1 216 SER n 
1 217 LEU n 
1 218 PRO n 
1 219 VAL n 
1 220 GLU n 
1 221 LYS n 
1 222 ALA n 
1 223 ALA n 
1 224 THR n 
1 225 THR n 
1 226 ARG n 
1 227 GLN n 
1 228 PRO n 
1 229 GLU n 
1 230 HIS n 
1 231 SER n 
1 232 ASN n 
1 233 PRO n 
1 234 LEU n 
1 235 GLU n 
1 236 CYS n 
1 237 ASP n 
1 238 THR n 
1 239 LEU n 
1 240 CYS n 
1 241 PHE n 
1 242 MET n 
1 243 GLY n 
1 244 THR n 
1 245 THR n 
1 246 VAL n 
1 247 VAL n 
1 248 SER n 
1 249 GLY n 
1 250 THR n 
1 251 ALA n 
1 252 GLN n 
1 253 ALA n 
1 254 MET n 
1 255 VAL n 
1 256 ILE n 
1 257 ALA n 
1 258 THR n 
1 259 GLY n 
1 260 ALA n 
1 261 ASN n 
1 262 THR n 
1 263 TRP n 
1 264 PHE n 
1 265 GLY n 
1 266 GLN n 
1 267 LEU n 
1 268 ALA n 
1 269 GLY n 
1 270 ARG n 
1 271 VAL n 
1 272 SER n 
1 273 GLU n 
1 274 GLN n 
1 275 GLU n 
1 276 SER n 
1 277 GLU n 
1 278 PRO n 
1 279 ASN n 
1 280 ALA n 
1 281 PHE n 
1 282 GLN n 
1 283 GLN n 
1 284 GLY n 
1 285 ILE n 
1 286 SER n 
1 287 ARG n 
1 288 VAL n 
1 289 SER n 
1 290 MET n 
1 291 LEU n 
1 292 LEU n 
1 293 ILE n 
1 294 ARG n 
1 295 PHE n 
1 296 MET n 
1 297 LEU n 
1 298 VAL n 
1 299 MET n 
1 300 ALA n 
1 301 PRO n 
1 302 VAL n 
1 303 VAL n 
1 304 LEU n 
1 305 LEU n 
1 306 ILE n 
1 307 ASN n 
1 308 GLY n 
1 309 TYR n 
1 310 THR n 
1 311 LYS n 
1 312 GLY n 
1 313 ASP n 
1 314 TRP n 
1 315 TRP n 
1 316 GLU n 
1 317 ALA n 
1 318 ALA n 
1 319 LEU n 
1 320 PHE n 
1 321 ALA n 
1 322 LEU n 
1 323 SER n 
1 324 VAL n 
1 325 ALA n 
1 326 VAL n 
1 327 GLY n 
1 328 LEU n 
1 329 THR n 
1 330 PRO n 
1 331 GLU n 
1 332 MET n 
1 333 LEU n 
1 334 PRO n 
1 335 MET n 
1 336 ILE n 
1 337 VAL n 
1 338 THR n 
1 339 SER n 
1 340 THR n 
1 341 LEU n 
1 342 ALA n 
1 343 ARG n 
1 344 GLY n 
1 345 ALA n 
1 346 VAL n 
1 347 LYS n 
1 348 LEU n 
1 349 SER n 
1 350 LYS n 
1 351 GLN n 
1 352 LYS n 
1 353 VAL n 
1 354 ILE n 
1 355 VAL n 
1 356 LYS n 
1 357 HIS n 
1 358 LEU n 
1 359 ASP n 
1 360 ALA n 
1 361 ILE n 
1 362 GLN n 
1 363 ASN n 
1 364 PHE n 
1 365 GLY n 
1 366 ALA n 
1 367 MET n 
1 368 ASP n 
1 369 ILE n 
1 370 LEU n 
1 371 CYS n 
1 372 THR n 
1 373 ASP n 
1 374 LYS n 
1 375 THR n 
1 376 GLY n 
1 377 THR n 
1 378 LEU n 
1 379 THR n 
1 380 GLN n 
1 381 ASP n 
1 382 LYS n 
1 383 ILE n 
1 384 VAL n 
1 385 LEU n 
1 386 GLU n 
1 387 ASN n 
1 388 HIS n 
1 389 THR n 
1 390 ASP n 
1 391 ILE n 
1 392 SER n 
1 393 GLY n 
1 394 LYS n 
1 395 THR n 
1 396 SER n 
1 397 GLU n 
1 398 ARG n 
1 399 VAL n 
1 400 LEU n 
1 401 HIS n 
1 402 SER n 
1 403 ALA n 
1 404 TRP n 
1 405 LEU n 
1 406 ASN n 
1 407 SER n 
1 408 HIS n 
1 409 TYR n 
1 410 GLN n 
1 411 THR n 
1 412 GLY n 
1 413 LEU n 
1 414 LYS n 
1 415 ASN n 
1 416 LEU n 
1 417 LEU n 
1 418 ASP n 
1 419 THR n 
1 420 ALA n 
1 421 VAL n 
1 422 LEU n 
1 423 GLU n 
1 424 GLY n 
1 425 THR n 
1 426 ASP n 
1 427 GLU n 
1 428 GLU n 
1 429 SER n 
1 430 ALA n 
1 431 ARG n 
1 432 SER n 
1 433 LEU n 
1 434 ALA n 
1 435 SER n 
1 436 ARG n 
1 437 TRP n 
1 438 GLN n 
1 439 LYS n 
1 440 ILE n 
1 441 ASP n 
1 442 GLU n 
1 443 ILE n 
1 444 PRO n 
1 445 PHE n 
1 446 ASP n 
1 447 PHE n 
1 448 GLU n 
1 449 ARG n 
1 450 ARG n 
1 451 ARG n 
1 452 MET n 
1 453 SER n 
1 454 VAL n 
1 455 VAL n 
1 456 VAL n 
1 457 ALA n 
1 458 GLU n 
1 459 ASN n 
1 460 THR n 
1 461 GLU n 
1 462 HIS n 
1 463 HIS n 
1 464 GLN n 
1 465 LEU n 
1 466 VAL n 
1 467 CYS n 
1 468 LYS n 
1 469 GLY n 
1 470 ALA n 
1 471 LEU n 
1 472 GLN n 
1 473 GLU n 
1 474 ILE n 
1 475 LEU n 
1 476 ASN n 
1 477 VAL n 
1 478 CYS n 
1 479 SER n 
1 480 GLN n 
1 481 VAL n 
1 482 ARG n 
1 483 HIS n 
1 484 ASN n 
1 485 GLY n 
1 486 GLU n 
1 487 ILE n 
1 488 VAL n 
1 489 PRO n 
1 490 LEU n 
1 491 ASP n 
1 492 ASP n 
1 493 ILE n 
1 494 MET n 
1 495 LEU n 
1 496 ARG n 
1 497 LYS n 
1 498 ILE n 
1 499 LYS n 
1 500 ARG n 
1 501 VAL n 
1 502 THR n 
1 503 ASP n 
1 504 THR n 
1 505 LEU n 
1 506 ASN n 
1 507 ARG n 
1 508 GLN n 
1 509 GLY n 
1 510 LEU n 
1 511 ARG n 
1 512 VAL n 
1 513 VAL n 
1 514 ALA n 
1 515 VAL n 
1 516 ALA n 
1 517 THR n 
1 518 LYS n 
1 519 TYR n 
1 520 LEU n 
1 521 PRO n 
1 522 ALA n 
1 523 ARG n 
1 524 GLU n 
1 525 GLY n 
1 526 ASP n 
1 527 TYR n 
1 528 GLN n 
1 529 ARG n 
1 530 ALA n 
1 531 ASP n 
1 532 GLU n 
1 533 SER n 
1 534 ASP n 
1 535 LEU n 
1 536 ILE n 
1 537 LEU n 
1 538 GLU n 
1 539 GLY n 
1 540 TYR n 
1 541 ILE n 
1 542 ALA n 
1 543 PHE n 
1 544 LEU n 
1 545 ASP n 
1 546 PRO n 
1 547 PRO n 
1 548 LYS n 
1 549 GLU n 
1 550 THR n 
1 551 THR n 
1 552 ALA n 
1 553 PRO n 
1 554 ALA n 
1 555 LEU n 
1 556 LYS n 
1 557 ALA n 
1 558 LEU n 
1 559 LYS n 
1 560 ALA n 
1 561 SER n 
1 562 GLY n 
1 563 ILE n 
1 564 THR n 
1 565 VAL n 
1 566 LYS n 
1 567 ILE n 
1 568 LEU n 
1 569 THR n 
1 570 GLY n 
1 571 ASP n 
1 572 SER n 
1 573 GLU n 
1 574 LEU n 
1 575 VAL n 
1 576 ALA n 
1 577 ALA n 
1 578 LYS n 
1 579 VAL n 
1 580 CYS n 
1 581 HIS n 
1 582 GLU n 
1 583 VAL n 
1 584 GLY n 
1 585 LEU n 
1 586 ASP n 
1 587 ALA n 
1 588 GLY n 
1 589 GLU n 
1 590 VAL n 
1 591 VAL n 
1 592 ILE n 
1 593 GLY n 
1 594 SER n 
1 595 ASP n 
1 596 ILE n 
1 597 GLU n 
1 598 THR n 
1 599 LEU n 
1 600 SER n 
1 601 ASP n 
1 602 ASP n 
1 603 GLU n 
1 604 LEU n 
1 605 ALA n 
1 606 ASN n 
1 607 LEU n 
1 608 ALA n 
1 609 GLN n 
1 610 ARG n 
1 611 THR n 
1 612 THR n 
1 613 LEU n 
1 614 PHE n 
1 615 ALA n 
1 616 ARG n 
1 617 LEU n 
1 618 THR n 
1 619 PRO n 
1 620 MET n 
1 621 HIS n 
1 622 LYS n 
1 623 GLU n 
1 624 ARG n 
1 625 ILE n 
1 626 VAL n 
1 627 THR n 
1 628 LEU n 
1 629 LEU n 
1 630 LYS n 
1 631 ARG n 
1 632 GLU n 
1 633 GLY n 
1 634 HIS n 
1 635 VAL n 
1 636 VAL n 
1 637 GLY n 
1 638 PHE n 
1 639 MET n 
1 640 GLY n 
1 641 ASP n 
1 642 GLY n 
1 643 ILE n 
1 644 ASN n 
1 645 ASP n 
1 646 ALA n 
1 647 PRO n 
1 648 ALA n 
1 649 LEU n 
1 650 ARG n 
1 651 ALA n 
1 652 ALA n 
1 653 ASP n 
1 654 ILE n 
1 655 GLY n 
1 656 ILE n 
1 657 SER n 
1 658 VAL n 
1 659 ASP n 
1 660 GLY n 
1 661 ALA n 
1 662 VAL n 
1 663 ASP n 
1 664 ILE n 
1 665 ALA n 
1 666 ARG n 
1 667 GLU n 
1 668 ALA n 
1 669 ALA n 
1 670 ASP n 
1 671 ILE n 
1 672 ILE n 
1 673 LEU n 
1 674 LEU n 
1 675 GLU n 
1 676 LYS n 
1 677 SER n 
1 678 LEU n 
1 679 MET n 
1 680 VAL n 
1 681 LEU n 
1 682 GLU n 
1 683 GLU n 
1 684 GLY n 
1 685 VAL n 
1 686 ILE n 
1 687 GLU n 
1 688 GLY n 
1 689 ARG n 
1 690 ARG n 
1 691 THR n 
1 692 PHE n 
1 693 ALA n 
1 694 ASN n 
1 695 MET n 
1 696 LEU n 
1 697 LYS n 
1 698 TYR n 
1 699 ILE n 
1 700 LYS n 
1 701 MET n 
1 702 THR n 
1 703 ALA n 
1 704 SER n 
1 705 SER n 
1 706 ASN n 
1 707 PHE n 
1 708 GLY n 
1 709 ASN n 
1 710 VAL n 
1 711 PHE n 
1 712 SER n 
1 713 VAL n 
1 714 LEU n 
1 715 VAL n 
1 716 ALA n 
1 717 SER n 
1 718 ALA n 
1 719 PHE n 
1 720 LEU n 
1 721 PRO n 
1 722 PHE n 
1 723 LEU n 
1 724 PRO n 
1 725 MET n 
1 726 LEU n 
1 727 PRO n 
1 728 LEU n 
1 729 HIS n 
1 730 LEU n 
1 731 LEU n 
1 732 ILE n 
1 733 GLN n 
1 734 ASN n 
1 735 LEU n 
1 736 LEU n 
1 737 TYR n 
1 738 ASP n 
1 739 VAL n 
1 740 SER n 
1 741 GLN n 
1 742 VAL n 
1 743 ALA n 
1 744 ILE n 
1 745 PRO n 
1 746 PHE n 
1 747 ASP n 
1 748 ASN n 
1 749 VAL n 
1 750 ASP n 
1 751 ASP n 
1 752 GLU n 
1 753 GLN n 
1 754 ILE n 
1 755 GLN n 
1 756 LYS n 
1 757 PRO n 
1 758 GLN n 
1 759 ARG n 
1 760 TRP n 
1 761 ASN n 
1 762 PRO n 
1 763 ALA n 
1 764 ASP n 
1 765 LEU n 
1 766 GLY n 
1 767 ARG n 
1 768 PHE n 
1 769 MET n 
1 770 ILE n 
1 771 PHE n 
1 772 PHE n 
1 773 GLY n 
1 774 PRO n 
1 775 ILE n 
1 776 SER n 
1 777 SER n 
1 778 ILE n 
1 779 PHE n 
1 780 ASP n 
1 781 ILE n 
1 782 LEU n 
1 783 THR n 
1 784 PHE n 
1 785 CYS n 
1 786 LEU n 
1 787 MET n 
1 788 TRP n 
1 789 TRP n 
1 790 VAL n 
1 791 PHE n 
1 792 HIS n 
1 793 ALA n 
1 794 ASN n 
1 795 THR n 
1 796 PRO n 
1 797 GLU n 
1 798 THR n 
1 799 GLN n 
1 800 THR n 
1 801 LEU n 
1 802 PHE n 
1 803 GLN n 
1 804 SER n 
1 805 GLY n 
1 806 TRP n 
1 807 PHE n 
1 808 VAL n 
1 809 VAL n 
1 810 GLY n 
1 811 LEU n 
1 812 LEU n 
1 813 SER n 
1 814 GLN n 
1 815 THR n 
1 816 LEU n 
1 817 ILE n 
1 818 VAL n 
1 819 HIS n 
1 820 MET n 
1 821 ILE n 
1 822 ARG n 
1 823 THR n 
1 824 ARG n 
1 825 ARG n 
1 826 VAL n 
1 827 PRO n 
1 828 PHE n 
1 829 ILE n 
1 830 GLN n 
1 831 SER n 
1 832 CYS n 
1 833 ALA n 
1 834 SER n 
1 835 TRP n 
1 836 PRO n 
1 837 LEU n 
1 838 MET n 
1 839 ILE n 
1 840 MET n 
1 841 THR n 
1 842 VAL n 
1 843 ILE n 
1 844 VAL n 
1 845 MET n 
1 846 ILE n 
1 847 VAL n 
1 848 GLY n 
1 849 ILE n 
1 850 ALA n 
1 851 LEU n 
1 852 PRO n 
1 853 PHE n 
1 854 SER n 
1 855 PRO n 
1 856 LEU n 
1 857 ALA n 
1 858 SER n 
1 859 TYR n 
1 860 LEU n 
1 861 GLN n 
1 862 LEU n 
1 863 GLN n 
1 864 ALA n 
1 865 LEU n 
1 866 PRO n 
1 867 LEU n 
1 868 SER n 
1 869 TYR n 
1 870 PHE n 
1 871 PRO n 
1 872 TRP n 
1 873 LEU n 
1 874 VAL n 
1 875 ALA n 
1 876 ILE n 
1 877 LEU n 
1 878 ALA n 
1 879 GLY n 
1 880 TYR n 
1 881 MET n 
1 882 THR n 
1 883 LEU n 
1 884 THR n 
1 885 GLN n 
1 886 LEU n 
1 887 VAL n 
1 888 LYS n 
1 889 GLY n 
1 890 PHE n 
1 891 TYR n 
1 892 SER n 
1 893 ARG n 
1 894 ARG n 
1 895 TYR n 
1 896 GLY n 
1 897 TRP n 
1 898 GLN n 
1 899 HIS n 
1 900 HIS n 
1 901 HIS n 
1 902 HIS n 
1 903 HIS n 
1 904 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   904 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 mgtA 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    'Escherichia coli K-12' 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli K-12' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     83333 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'Escherichia coli C43 (DE3)' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          'Bacterial expression, coexpression' 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   
;pETDuet-1 is designed for the coexpression of two target genes. pETDuet-1 carries the pBR322-derived ColE1 replicon, the lacI gene and the ampicillin resistance gene.
;
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pETDuet-1 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
MG  non-polymer         . 'MAGNESIUM ION' ? 'Mg 2'           24.305  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   PHE 2   2   2   PHE PHE A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ILE 5   5   5   ILE ILE A . n 
A 1 6   PHE 6   6   6   PHE PHE A . n 
A 1 7   THR 7   7   7   THR THR A . n 
A 1 8   ARG 8   8   8   ARG ARG A . n 
A 1 9   LEU 9   9   9   LEU LEU A . n 
A 1 10  ILE 10  10  10  ILE ILE A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  HIS 12  12  12  HIS HIS A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  ARG 16  16  16  ARG ARG A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  ARG 20  20  20  ARG ARG A . n 
A 1 21  ASP 21  21  21  ASP ASP A . n 
A 1 22  PRO 22  22  22  PRO PRO A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  PRO 24  24  24  PRO PRO A . n 
A 1 25  GLY 25  25  25  GLY GLY A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  GLN 27  27  27  GLN GLN A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  ASN 31  31  31  ASN ASN A . n 
A 1 32  THR 32  32  32  THR THR A . n 
A 1 33  VAL 33  33  33  VAL VAL A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  PRO 36  36  36  PRO PRO A . n 
A 1 37  SER 37  37  37  SER SER A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  CYS 42  42  42  CYS CYS A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  LYS 44  44  44  LYS LYS A . n 
A 1 45  MET 45  45  45  MET MET A . n 
A 1 46  ALA 46  46  46  ALA ALA A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  MET 48  48  48  MET MET A . n 
A 1 49  PRO 49  49  49  PRO PRO A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  GLU 52  52  52  GLU GLU A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  TRP 54  54  54  TRP TRP A . n 
A 1 55  LYS 55  55  55  LYS LYS A . n 
A 1 56  THR 56  56  56  THR THR A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  GLU 62  62  62  GLU GLU A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  GLN 66  66  66  GLN GLN A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  LYS 80  80  80  LYS LYS A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  GLN 84  84  84  GLN GLN A . n 
A 1 85  GLN 85  85  85  GLN GLN A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  SER 87  87  87  SER SER A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  TRP 89  89  89  TRP TRP A . n 
A 1 90  TRP 90  90  90  TRP TRP A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  HIS 92  92  92  HIS HIS A . n 
A 1 93  LEU 93  93  93  LEU LEU A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  CYS 96  96  96  CYS CYS A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  ARG 98  98  98  ARG ARG A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 ILE 103 103 103 ILE ILE A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 ILE 111 111 111 ILE ILE A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 TYR 113 113 113 TYR TYR A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 ALA 120 120 120 ALA ALA A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 MET 127 127 127 MET MET A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 LYS 150 150 150 LYS LYS A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 MET 152 152 152 MET MET A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 ASN 155 155 155 ASN ASN A . n 
A 1 156 THR 156 156 156 THR THR A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ARG 161 161 161 ARG ARG A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 LYS 166 166 166 LYS LYS A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 ASN 169 169 169 ASN ASN A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 TRP 171 171 171 TRP TRP A . n 
A 1 172 LEU 172 172 172 LEU LEU A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ILE 174 174 174 ILE ILE A . n 
A 1 175 PRO 175 175 175 PRO PRO A . n 
A 1 176 ILE 176 176 176 ILE ILE A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 ILE 185 185 185 ILE ILE A . n 
A 1 186 LYS 186 186 186 LYS LYS A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 ALA 189 189 189 ALA ALA A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ASP 191 191 191 ASP ASP A . n 
A 1 192 MET 192 192 192 MET MET A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 ILE 199 199 199 ILE ILE A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 GLN 201 201 201 GLN GLN A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 VAL 207 207 207 VAL VAL A . n 
A 1 208 ALA 208 208 208 ALA ALA A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 SER 211 211 211 SER SER A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 GLU 220 220 220 GLU GLU A . n 
A 1 221 LYS 221 221 221 LYS LYS A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 GLU 229 229 229 GLU GLU A . n 
A 1 230 HIS 230 230 230 HIS HIS A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 ASN 232 232 232 ASN ASN A . n 
A 1 233 PRO 233 233 233 PRO PRO A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 GLU 235 235 235 GLU GLU A . n 
A 1 236 CYS 236 236 236 CYS CYS A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 THR 238 238 238 THR THR A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 CYS 240 240 240 CYS CYS A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 THR 245 245 245 THR THR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 SER 248 248 248 SER SER A . n 
A 1 249 GLY 249 249 249 GLY GLY A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 GLN 252 252 252 GLN GLN A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 MET 254 254 254 MET MET A . n 
A 1 255 VAL 255 255 255 VAL VAL A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 ASN 261 261 261 ASN ASN A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 TRP 263 263 263 TRP TRP A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 GLN 266 266 266 GLN GLN A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 VAL 271 271 271 VAL VAL A . n 
A 1 272 SER 272 272 272 SER SER A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 GLN 274 274 274 GLN GLN A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 PRO 278 278 278 PRO PRO A . n 
A 1 279 ASN 279 279 279 ASN ASN A . n 
A 1 280 ALA 280 280 280 ALA ALA A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 GLN 282 282 282 GLN GLN A . n 
A 1 283 GLN 283 283 283 GLN GLN A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 SER 286 286 286 SER SER A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 MET 290 290 290 MET MET A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 PHE 295 295 295 PHE PHE A . n 
A 1 296 MET 296 296 296 MET MET A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 MET 299 299 299 MET MET A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 PRO 301 301 301 PRO PRO A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 LEU 304 304 304 LEU LEU A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ILE 306 306 306 ILE ILE A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 TYR 309 309 309 TYR TYR A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 TRP 314 314 314 TRP TRP A . n 
A 1 315 TRP 315 315 315 TRP TRP A . n 
A 1 316 GLU 316 316 316 GLU GLU A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 PHE 320 320 320 PHE PHE A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 SER 323 323 323 SER SER A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 VAL 326 326 326 VAL VAL A . n 
A 1 327 GLY 327 327 327 GLY GLY A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 PRO 330 330 330 PRO PRO A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 MET 332 332 332 MET MET A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 MET 335 335 335 MET MET A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 THR 338 338 338 THR THR A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 ARG 343 343 343 ARG ARG A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 ALA 345 345 345 ALA ALA A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 SER 349 349 349 SER SER A . n 
A 1 350 LYS 350 350 350 LYS LYS A . n 
A 1 351 GLN 351 351 351 GLN GLN A . n 
A 1 352 LYS 352 352 352 LYS LYS A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 ILE 354 354 354 ILE ILE A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 LYS 356 356 356 LYS LYS A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 LEU 358 358 358 LEU LEU A . n 
A 1 359 ASP 359 359 359 ASP ASP A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ILE 361 361 361 ILE ILE A . n 
A 1 362 GLN 362 362 362 GLN GLN A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 PHE 364 364 364 PHE PHE A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 ILE 369 369 369 ILE ILE A . n 
A 1 370 LEU 370 370 370 LEU LEU A . n 
A 1 371 CYS 371 371 371 CYS CYS A . n 
A 1 372 THR 372 372 372 THR THR A . n 
A 1 373 ASP 373 373 373 ASP ASP A . n 
A 1 374 LYS 374 374 374 LYS LYS A . n 
A 1 375 THR 375 375 375 THR THR A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 THR 377 377 377 THR THR A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 GLN 380 380 380 GLN GLN A . n 
A 1 381 ASP 381 381 381 ASP ASP A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 LEU 385 385 385 LEU LEU A . n 
A 1 386 GLU 386 386 386 GLU GLU A . n 
A 1 387 ASN 387 387 387 ASN ASN A . n 
A 1 388 HIS 388 388 388 HIS HIS A . n 
A 1 389 THR 389 389 389 THR THR A . n 
A 1 390 ASP 390 390 390 ASP ASP A . n 
A 1 391 ILE 391 391 391 ILE ILE A . n 
A 1 392 SER 392 392 392 SER SER A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 THR 395 395 395 THR THR A . n 
A 1 396 SER 396 396 396 SER SER A . n 
A 1 397 GLU 397 397 397 GLU GLU A . n 
A 1 398 ARG 398 398 398 ARG ARG A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 HIS 401 401 401 HIS HIS A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 ALA 403 403 403 ALA ALA A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 ASN 406 406 406 ASN ASN A . n 
A 1 407 SER 407 407 407 SER SER A . n 
A 1 408 HIS 408 408 408 HIS HIS A . n 
A 1 409 TYR 409 409 409 TYR TYR A . n 
A 1 410 GLN 410 410 410 GLN GLN A . n 
A 1 411 THR 411 411 411 THR THR A . n 
A 1 412 GLY 412 412 412 GLY GLY A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 LYS 414 414 414 LYS LYS A . n 
A 1 415 ASN 415 415 415 ASN ASN A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 ASP 418 418 418 ASP ASP A . n 
A 1 419 THR 419 419 419 THR THR A . n 
A 1 420 ALA 420 420 420 ALA ALA A . n 
A 1 421 VAL 421 421 421 VAL VAL A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 GLU 423 423 423 GLU GLU A . n 
A 1 424 GLY 424 424 424 GLY GLY A . n 
A 1 425 THR 425 425 425 THR THR A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 GLU 427 427 427 GLU GLU A . n 
A 1 428 GLU 428 428 428 GLU GLU A . n 
A 1 429 SER 429 429 429 SER SER A . n 
A 1 430 ALA 430 430 430 ALA ALA A . n 
A 1 431 ARG 431 431 431 ARG ARG A . n 
A 1 432 SER 432 432 432 SER SER A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 SER 435 435 435 SER SER A . n 
A 1 436 ARG 436 436 436 ARG ARG A . n 
A 1 437 TRP 437 437 437 TRP TRP A . n 
A 1 438 GLN 438 438 438 GLN GLN A . n 
A 1 439 LYS 439 439 439 LYS LYS A . n 
A 1 440 ILE 440 440 440 ILE ILE A . n 
A 1 441 ASP 441 441 441 ASP ASP A . n 
A 1 442 GLU 442 442 442 GLU GLU A . n 
A 1 443 ILE 443 443 443 ILE ILE A . n 
A 1 444 PRO 444 444 444 PRO PRO A . n 
A 1 445 PHE 445 445 445 PHE PHE A . n 
A 1 446 ASP 446 446 446 ASP ASP A . n 
A 1 447 PHE 447 447 447 PHE PHE A . n 
A 1 448 GLU 448 448 448 GLU GLU A . n 
A 1 449 ARG 449 449 449 ARG ARG A . n 
A 1 450 ARG 450 450 450 ARG ARG A . n 
A 1 451 ARG 451 451 451 ARG ARG A . n 
A 1 452 MET 452 452 452 MET MET A . n 
A 1 453 SER 453 453 453 SER SER A . n 
A 1 454 VAL 454 454 454 VAL VAL A . n 
A 1 455 VAL 455 455 455 VAL VAL A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 ALA 457 457 457 ALA ALA A . n 
A 1 458 GLU 458 458 458 GLU GLU A . n 
A 1 459 ASN 459 459 459 ASN ASN A . n 
A 1 460 THR 460 460 460 THR THR A . n 
A 1 461 GLU 461 461 461 GLU GLU A . n 
A 1 462 HIS 462 462 462 HIS HIS A . n 
A 1 463 HIS 463 463 463 HIS HIS A . n 
A 1 464 GLN 464 464 464 GLN GLN A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 CYS 467 467 467 CYS CYS A . n 
A 1 468 LYS 468 468 468 LYS LYS A . n 
A 1 469 GLY 469 469 469 GLY GLY A . n 
A 1 470 ALA 470 470 470 ALA ALA A . n 
A 1 471 LEU 471 471 471 LEU LEU A . n 
A 1 472 GLN 472 472 472 GLN GLN A . n 
A 1 473 GLU 473 473 473 GLU GLU A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 ASN 476 476 476 ASN ASN A . n 
A 1 477 VAL 477 477 477 VAL VAL A . n 
A 1 478 CYS 478 478 478 CYS CYS A . n 
A 1 479 SER 479 479 479 SER SER A . n 
A 1 480 GLN 480 480 480 GLN GLN A . n 
A 1 481 VAL 481 481 481 VAL VAL A . n 
A 1 482 ARG 482 482 482 ARG ARG A . n 
A 1 483 HIS 483 483 483 HIS HIS A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 GLY 485 485 485 GLY GLY A . n 
A 1 486 GLU 486 486 486 GLU GLU A . n 
A 1 487 ILE 487 487 487 ILE ILE A . n 
A 1 488 VAL 488 488 488 VAL VAL A . n 
A 1 489 PRO 489 489 489 PRO PRO A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 ASP 491 491 491 ASP ASP A . n 
A 1 492 ASP 492 492 492 ASP ASP A . n 
A 1 493 ILE 493 493 493 ILE ILE A . n 
A 1 494 MET 494 494 494 MET MET A . n 
A 1 495 LEU 495 495 495 LEU LEU A . n 
A 1 496 ARG 496 496 496 ARG ARG A . n 
A 1 497 LYS 497 497 497 LYS LYS A . n 
A 1 498 ILE 498 498 498 ILE ILE A . n 
A 1 499 LYS 499 499 499 LYS LYS A . n 
A 1 500 ARG 500 500 500 ARG ARG A . n 
A 1 501 VAL 501 501 501 VAL VAL A . n 
A 1 502 THR 502 502 502 THR THR A . n 
A 1 503 ASP 503 503 503 ASP ASP A . n 
A 1 504 THR 504 504 504 THR THR A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 ASN 506 506 506 ASN ASN A . n 
A 1 507 ARG 507 507 507 ARG ARG A . n 
A 1 508 GLN 508 508 508 GLN GLN A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 ARG 511 511 511 ARG ARG A . n 
A 1 512 VAL 512 512 512 VAL VAL A . n 
A 1 513 VAL 513 513 513 VAL VAL A . n 
A 1 514 ALA 514 514 514 ALA ALA A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 ALA 516 516 516 ALA ALA A . n 
A 1 517 THR 517 517 517 THR THR A . n 
A 1 518 LYS 518 518 518 LYS LYS A . n 
A 1 519 TYR 519 519 519 TYR TYR A . n 
A 1 520 LEU 520 520 520 LEU LEU A . n 
A 1 521 PRO 521 521 521 PRO PRO A . n 
A 1 522 ALA 522 522 522 ALA ALA A . n 
A 1 523 ARG 523 523 523 ARG ARG A . n 
A 1 524 GLU 524 524 524 GLU GLU A . n 
A 1 525 GLY 525 525 525 GLY GLY A . n 
A 1 526 ASP 526 526 526 ASP ASP A . n 
A 1 527 TYR 527 527 527 TYR TYR A . n 
A 1 528 GLN 528 528 528 GLN GLN A . n 
A 1 529 ARG 529 529 529 ARG ARG A . n 
A 1 530 ALA 530 530 530 ALA ALA A . n 
A 1 531 ASP 531 531 531 ASP ASP A . n 
A 1 532 GLU 532 532 532 GLU GLU A . n 
A 1 533 SER 533 533 533 SER SER A . n 
A 1 534 ASP 534 534 534 ASP ASP A . n 
A 1 535 LEU 535 535 535 LEU LEU A . n 
A 1 536 ILE 536 536 536 ILE ILE A . n 
A 1 537 LEU 537 537 537 LEU LEU A . n 
A 1 538 GLU 538 538 538 GLU GLU A . n 
A 1 539 GLY 539 539 539 GLY GLY A . n 
A 1 540 TYR 540 540 540 TYR TYR A . n 
A 1 541 ILE 541 541 541 ILE ILE A . n 
A 1 542 ALA 542 542 542 ALA ALA A . n 
A 1 543 PHE 543 543 543 PHE PHE A . n 
A 1 544 LEU 544 544 544 LEU LEU A . n 
A 1 545 ASP 545 545 545 ASP ASP A . n 
A 1 546 PRO 546 546 546 PRO PRO A . n 
A 1 547 PRO 547 547 547 PRO PRO A . n 
A 1 548 LYS 548 548 548 LYS LYS A . n 
A 1 549 GLU 549 549 549 GLU GLU A . n 
A 1 550 THR 550 550 550 THR THR A . n 
A 1 551 THR 551 551 551 THR THR A . n 
A 1 552 ALA 552 552 552 ALA ALA A . n 
A 1 553 PRO 553 553 553 PRO PRO A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 LYS 559 559 559 LYS LYS A . n 
A 1 560 ALA 560 560 560 ALA ALA A . n 
A 1 561 SER 561 561 561 SER SER A . n 
A 1 562 GLY 562 562 562 GLY GLY A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 THR 564 564 564 THR THR A . n 
A 1 565 VAL 565 565 565 VAL VAL A . n 
A 1 566 LYS 566 566 566 LYS LYS A . n 
A 1 567 ILE 567 567 567 ILE ILE A . n 
A 1 568 LEU 568 568 568 LEU LEU A . n 
A 1 569 THR 569 569 569 THR THR A . n 
A 1 570 GLY 570 570 570 GLY GLY A . n 
A 1 571 ASP 571 571 571 ASP ASP A . n 
A 1 572 SER 572 572 572 SER SER A . n 
A 1 573 GLU 573 573 573 GLU GLU A . n 
A 1 574 LEU 574 574 574 LEU LEU A . n 
A 1 575 VAL 575 575 575 VAL VAL A . n 
A 1 576 ALA 576 576 576 ALA ALA A . n 
A 1 577 ALA 577 577 577 ALA ALA A . n 
A 1 578 LYS 578 578 578 LYS LYS A . n 
A 1 579 VAL 579 579 579 VAL VAL A . n 
A 1 580 CYS 580 580 580 CYS CYS A . n 
A 1 581 HIS 581 581 581 HIS HIS A . n 
A 1 582 GLU 582 582 582 GLU GLU A . n 
A 1 583 VAL 583 583 583 VAL VAL A . n 
A 1 584 GLY 584 584 584 GLY GLY A . n 
A 1 585 LEU 585 585 585 LEU LEU A . n 
A 1 586 ASP 586 586 586 ASP ASP A . n 
A 1 587 ALA 587 587 587 ALA ALA A . n 
A 1 588 GLY 588 588 588 GLY GLY A . n 
A 1 589 GLU 589 589 589 GLU GLU A . n 
A 1 590 VAL 590 590 590 VAL VAL A . n 
A 1 591 VAL 591 591 591 VAL VAL A . n 
A 1 592 ILE 592 592 592 ILE ILE A . n 
A 1 593 GLY 593 593 593 GLY GLY A . n 
A 1 594 SER 594 594 594 SER SER A . n 
A 1 595 ASP 595 595 595 ASP ASP A . n 
A 1 596 ILE 596 596 596 ILE ILE A . n 
A 1 597 GLU 597 597 597 GLU GLU A . n 
A 1 598 THR 598 598 598 THR THR A . n 
A 1 599 LEU 599 599 599 LEU LEU A . n 
A 1 600 SER 600 600 600 SER SER A . n 
A 1 601 ASP 601 601 601 ASP ASP A . n 
A 1 602 ASP 602 602 602 ASP ASP A . n 
A 1 603 GLU 603 603 603 GLU GLU A . n 
A 1 604 LEU 604 604 604 LEU LEU A . n 
A 1 605 ALA 605 605 605 ALA ALA A . n 
A 1 606 ASN 606 606 606 ASN ASN A . n 
A 1 607 LEU 607 607 607 LEU LEU A . n 
A 1 608 ALA 608 608 608 ALA ALA A . n 
A 1 609 GLN 609 609 609 GLN GLN A . n 
A 1 610 ARG 610 610 610 ARG ARG A . n 
A 1 611 THR 611 611 611 THR THR A . n 
A 1 612 THR 612 612 612 THR THR A . n 
A 1 613 LEU 613 613 613 LEU LEU A . n 
A 1 614 PHE 614 614 614 PHE PHE A . n 
A 1 615 ALA 615 615 615 ALA ALA A . n 
A 1 616 ARG 616 616 616 ARG ARG A . n 
A 1 617 LEU 617 617 617 LEU LEU A . n 
A 1 618 THR 618 618 618 THR THR A . n 
A 1 619 PRO 619 619 619 PRO PRO A . n 
A 1 620 MET 620 620 620 MET MET A . n 
A 1 621 HIS 621 621 621 HIS HIS A . n 
A 1 622 LYS 622 622 622 LYS LYS A . n 
A 1 623 GLU 623 623 623 GLU GLU A . n 
A 1 624 ARG 624 624 624 ARG ARG A . n 
A 1 625 ILE 625 625 625 ILE ILE A . n 
A 1 626 VAL 626 626 626 VAL VAL A . n 
A 1 627 THR 627 627 627 THR THR A . n 
A 1 628 LEU 628 628 628 LEU LEU A . n 
A 1 629 LEU 629 629 629 LEU LEU A . n 
A 1 630 LYS 630 630 630 LYS LYS A . n 
A 1 631 ARG 631 631 631 ARG ARG A . n 
A 1 632 GLU 632 632 632 GLU GLU A . n 
A 1 633 GLY 633 633 633 GLY GLY A . n 
A 1 634 HIS 634 634 634 HIS HIS A . n 
A 1 635 VAL 635 635 635 VAL VAL A . n 
A 1 636 VAL 636 636 636 VAL VAL A . n 
A 1 637 GLY 637 637 637 GLY GLY A . n 
A 1 638 PHE 638 638 638 PHE PHE A . n 
A 1 639 MET 639 639 639 MET MET A . n 
A 1 640 GLY 640 640 640 GLY GLY A . n 
A 1 641 ASP 641 641 641 ASP ASP A . n 
A 1 642 GLY 642 642 642 GLY GLY A . n 
A 1 643 ILE 643 643 643 ILE ILE A . n 
A 1 644 ASN 644 644 644 ASN ASN A . n 
A 1 645 ASP 645 645 645 ASP ASP A . n 
A 1 646 ALA 646 646 646 ALA ALA A . n 
A 1 647 PRO 647 647 647 PRO PRO A . n 
A 1 648 ALA 648 648 648 ALA ALA A . n 
A 1 649 LEU 649 649 649 LEU LEU A . n 
A 1 650 ARG 650 650 650 ARG ARG A . n 
A 1 651 ALA 651 651 651 ALA ALA A . n 
A 1 652 ALA 652 652 652 ALA ALA A . n 
A 1 653 ASP 653 653 653 ASP ASP A . n 
A 1 654 ILE 654 654 654 ILE ILE A . n 
A 1 655 GLY 655 655 655 GLY GLY A . n 
A 1 656 ILE 656 656 656 ILE ILE A . n 
A 1 657 SER 657 657 657 SER SER A . n 
A 1 658 VAL 658 658 658 VAL VAL A . n 
A 1 659 ASP 659 659 659 ASP ASP A . n 
A 1 660 GLY 660 660 660 GLY GLY A . n 
A 1 661 ALA 661 661 661 ALA ALA A . n 
A 1 662 VAL 662 662 662 VAL VAL A . n 
A 1 663 ASP 663 663 663 ASP ASP A . n 
A 1 664 ILE 664 664 664 ILE ILE A . n 
A 1 665 ALA 665 665 665 ALA ALA A . n 
A 1 666 ARG 666 666 666 ARG ARG A . n 
A 1 667 GLU 667 667 667 GLU GLU A . n 
A 1 668 ALA 668 668 668 ALA ALA A . n 
A 1 669 ALA 669 669 669 ALA ALA A . n 
A 1 670 ASP 670 670 670 ASP ASP A . n 
A 1 671 ILE 671 671 671 ILE ILE A . n 
A 1 672 ILE 672 672 672 ILE ILE A . n 
A 1 673 LEU 673 673 673 LEU LEU A . n 
A 1 674 LEU 674 674 674 LEU LEU A . n 
A 1 675 GLU 675 675 675 GLU GLU A . n 
A 1 676 LYS 676 676 676 LYS LYS A . n 
A 1 677 SER 677 677 677 SER SER A . n 
A 1 678 LEU 678 678 678 LEU LEU A . n 
A 1 679 MET 679 679 679 MET MET A . n 
A 1 680 VAL 680 680 680 VAL VAL A . n 
A 1 681 LEU 681 681 681 LEU LEU A . n 
A 1 682 GLU 682 682 682 GLU GLU A . n 
A 1 683 GLU 683 683 683 GLU GLU A . n 
A 1 684 GLY 684 684 684 GLY GLY A . n 
A 1 685 VAL 685 685 685 VAL VAL A . n 
A 1 686 ILE 686 686 686 ILE ILE A . n 
A 1 687 GLU 687 687 687 GLU GLU A . n 
A 1 688 GLY 688 688 688 GLY GLY A . n 
A 1 689 ARG 689 689 689 ARG ARG A . n 
A 1 690 ARG 690 690 690 ARG ARG A . n 
A 1 691 THR 691 691 691 THR THR A . n 
A 1 692 PHE 692 692 692 PHE PHE A . n 
A 1 693 ALA 693 693 693 ALA ALA A . n 
A 1 694 ASN 694 694 694 ASN ASN A . n 
A 1 695 MET 695 695 695 MET MET A . n 
A 1 696 LEU 696 696 696 LEU LEU A . n 
A 1 697 LYS 697 697 697 LYS LYS A . n 
A 1 698 TYR 698 698 698 TYR TYR A . n 
A 1 699 ILE 699 699 699 ILE ILE A . n 
A 1 700 LYS 700 700 700 LYS LYS A . n 
A 1 701 MET 701 701 701 MET MET A . n 
A 1 702 THR 702 702 702 THR THR A . n 
A 1 703 ALA 703 703 703 ALA ALA A . n 
A 1 704 SER 704 704 704 SER SER A . n 
A 1 705 SER 705 705 705 SER SER A . n 
A 1 706 ASN 706 706 706 ASN ASN A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 GLY 708 708 708 GLY GLY A . n 
A 1 709 ASN 709 709 709 ASN ASN A . n 
A 1 710 VAL 710 710 710 VAL VAL A . n 
A 1 711 PHE 711 711 711 PHE PHE A . n 
A 1 712 SER 712 712 712 SER SER A . n 
A 1 713 VAL 713 713 713 VAL VAL A . n 
A 1 714 LEU 714 714 714 LEU LEU A . n 
A 1 715 VAL 715 715 715 VAL VAL A . n 
A 1 716 ALA 716 716 716 ALA ALA A . n 
A 1 717 SER 717 717 717 SER SER A . n 
A 1 718 ALA 718 718 718 ALA ALA A . n 
A 1 719 PHE 719 719 719 PHE PHE A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 PRO 721 721 721 PRO PRO A . n 
A 1 722 PHE 722 722 722 PHE PHE A . n 
A 1 723 LEU 723 723 723 LEU LEU A . n 
A 1 724 PRO 724 724 724 PRO PRO A . n 
A 1 725 MET 725 725 725 MET MET A . n 
A 1 726 LEU 726 726 726 LEU LEU A . n 
A 1 727 PRO 727 727 727 PRO PRO A . n 
A 1 728 LEU 728 728 728 LEU LEU A . n 
A 1 729 HIS 729 729 729 HIS HIS A . n 
A 1 730 LEU 730 730 730 LEU LEU A . n 
A 1 731 LEU 731 731 731 LEU LEU A . n 
A 1 732 ILE 732 732 732 ILE ILE A . n 
A 1 733 GLN 733 733 733 GLN GLN A . n 
A 1 734 ASN 734 734 734 ASN ASN A . n 
A 1 735 LEU 735 735 735 LEU LEU A . n 
A 1 736 LEU 736 736 736 LEU LEU A . n 
A 1 737 TYR 737 737 737 TYR TYR A . n 
A 1 738 ASP 738 738 738 ASP ASP A . n 
A 1 739 VAL 739 739 739 VAL VAL A . n 
A 1 740 SER 740 740 740 SER SER A . n 
A 1 741 GLN 741 741 741 GLN GLN A . n 
A 1 742 VAL 742 742 742 VAL VAL A . n 
A 1 743 ALA 743 743 743 ALA ALA A . n 
A 1 744 ILE 744 744 744 ILE ILE A . n 
A 1 745 PRO 745 745 745 PRO PRO A . n 
A 1 746 PHE 746 746 746 PHE PHE A . n 
A 1 747 ASP 747 747 747 ASP ASP A . n 
A 1 748 ASN 748 748 748 ASN ASN A . n 
A 1 749 VAL 749 749 749 VAL VAL A . n 
A 1 750 ASP 750 750 750 ASP ASP A . n 
A 1 751 ASP 751 751 751 ASP ASP A . n 
A 1 752 GLU 752 752 752 GLU GLU A . n 
A 1 753 GLN 753 753 753 GLN GLN A . n 
A 1 754 ILE 754 754 754 ILE ILE A . n 
A 1 755 GLN 755 755 755 GLN GLN A . n 
A 1 756 LYS 756 756 756 LYS LYS A . n 
A 1 757 PRO 757 757 757 PRO PRO A . n 
A 1 758 GLN 758 758 758 GLN GLN A . n 
A 1 759 ARG 759 759 759 ARG ARG A . n 
A 1 760 TRP 760 760 760 TRP TRP A . n 
A 1 761 ASN 761 761 761 ASN ASN A . n 
A 1 762 PRO 762 762 762 PRO PRO A . n 
A 1 763 ALA 763 763 763 ALA ALA A . n 
A 1 764 ASP 764 764 764 ASP ASP A . n 
A 1 765 LEU 765 765 765 LEU LEU A . n 
A 1 766 GLY 766 766 766 GLY GLY A . n 
A 1 767 ARG 767 767 767 ARG ARG A . n 
A 1 768 PHE 768 768 768 PHE PHE A . n 
A 1 769 MET 769 769 769 MET MET A . n 
A 1 770 ILE 770 770 770 ILE ILE A . n 
A 1 771 PHE 771 771 771 PHE PHE A . n 
A 1 772 PHE 772 772 772 PHE PHE A . n 
A 1 773 GLY 773 773 773 GLY GLY A . n 
A 1 774 PRO 774 774 774 PRO PRO A . n 
A 1 775 ILE 775 775 775 ILE ILE A . n 
A 1 776 SER 776 776 776 SER SER A . n 
A 1 777 SER 777 777 777 SER SER A . n 
A 1 778 ILE 778 778 778 ILE ILE A . n 
A 1 779 PHE 779 779 779 PHE PHE A . n 
A 1 780 ASP 780 780 780 ASP ASP A . n 
A 1 781 ILE 781 781 781 ILE ILE A . n 
A 1 782 LEU 782 782 782 LEU LEU A . n 
A 1 783 THR 783 783 783 THR THR A . n 
A 1 784 PHE 784 784 784 PHE PHE A . n 
A 1 785 CYS 785 785 785 CYS CYS A . n 
A 1 786 LEU 786 786 786 LEU LEU A . n 
A 1 787 MET 787 787 787 MET MET A . n 
A 1 788 TRP 788 788 788 TRP TRP A . n 
A 1 789 TRP 789 789 789 TRP TRP A . n 
A 1 790 VAL 790 790 790 VAL VAL A . n 
A 1 791 PHE 791 791 791 PHE PHE A . n 
A 1 792 HIS 792 792 792 HIS HIS A . n 
A 1 793 ALA 793 793 793 ALA ALA A . n 
A 1 794 ASN 794 794 794 ASN ASN A . n 
A 1 795 THR 795 795 795 THR THR A . n 
A 1 796 PRO 796 796 796 PRO PRO A . n 
A 1 797 GLU 797 797 797 GLU GLU A . n 
A 1 798 THR 798 798 798 THR THR A . n 
A 1 799 GLN 799 799 799 GLN GLN A . n 
A 1 800 THR 800 800 800 THR THR A . n 
A 1 801 LEU 801 801 801 LEU LEU A . n 
A 1 802 PHE 802 802 802 PHE PHE A . n 
A 1 803 GLN 803 803 803 GLN GLN A . n 
A 1 804 SER 804 804 804 SER SER A . n 
A 1 805 GLY 805 805 805 GLY GLY A . n 
A 1 806 TRP 806 806 806 TRP TRP A . n 
A 1 807 PHE 807 807 807 PHE PHE A . n 
A 1 808 VAL 808 808 808 VAL VAL A . n 
A 1 809 VAL 809 809 809 VAL VAL A . n 
A 1 810 GLY 810 810 810 GLY GLY A . n 
A 1 811 LEU 811 811 811 LEU LEU A . n 
A 1 812 LEU 812 812 812 LEU LEU A . n 
A 1 813 SER 813 813 813 SER SER A . n 
A 1 814 GLN 814 814 814 GLN GLN A . n 
A 1 815 THR 815 815 815 THR THR A . n 
A 1 816 LEU 816 816 816 LEU LEU A . n 
A 1 817 ILE 817 817 817 ILE ILE A . n 
A 1 818 VAL 818 818 818 VAL VAL A . n 
A 1 819 HIS 819 819 819 HIS HIS A . n 
A 1 820 MET 820 820 820 MET MET A . n 
A 1 821 ILE 821 821 821 ILE ILE A . n 
A 1 822 ARG 822 822 822 ARG ARG A . n 
A 1 823 THR 823 823 823 THR THR A . n 
A 1 824 ARG 824 824 824 ARG ARG A . n 
A 1 825 ARG 825 825 825 ARG ARG A . n 
A 1 826 VAL 826 826 826 VAL VAL A . n 
A 1 827 PRO 827 827 827 PRO PRO A . n 
A 1 828 PHE 828 828 828 PHE PHE A . n 
A 1 829 ILE 829 829 829 ILE ILE A . n 
A 1 830 GLN 830 830 830 GLN GLN A . n 
A 1 831 SER 831 831 831 SER SER A . n 
A 1 832 CYS 832 832 832 CYS CYS A . n 
A 1 833 ALA 833 833 833 ALA ALA A . n 
A 1 834 SER 834 834 834 SER SER A . n 
A 1 835 TRP 835 835 835 TRP TRP A . n 
A 1 836 PRO 836 836 836 PRO PRO A . n 
A 1 837 LEU 837 837 837 LEU LEU A . n 
A 1 838 MET 838 838 838 MET MET A . n 
A 1 839 ILE 839 839 839 ILE ILE A . n 
A 1 840 MET 840 840 840 MET MET A . n 
A 1 841 THR 841 841 841 THR THR A . n 
A 1 842 VAL 842 842 842 VAL VAL A . n 
A 1 843 ILE 843 843 843 ILE ILE A . n 
A 1 844 VAL 844 844 844 VAL VAL A . n 
A 1 845 MET 845 845 845 MET MET A . n 
A 1 846 ILE 846 846 846 ILE ILE A . n 
A 1 847 VAL 847 847 847 VAL VAL A . n 
A 1 848 GLY 848 848 848 GLY GLY A . n 
A 1 849 ILE 849 849 849 ILE ILE A . n 
A 1 850 ALA 850 850 850 ALA ALA A . n 
A 1 851 LEU 851 851 851 LEU LEU A . n 
A 1 852 PRO 852 852 852 PRO PRO A . n 
A 1 853 PHE 853 853 853 PHE PHE A . n 
A 1 854 SER 854 854 854 SER SER A . n 
A 1 855 PRO 855 855 855 PRO PRO A . n 
A 1 856 LEU 856 856 856 LEU LEU A . n 
A 1 857 ALA 857 857 857 ALA ALA A . n 
A 1 858 SER 858 858 858 SER SER A . n 
A 1 859 TYR 859 859 859 TYR TYR A . n 
A 1 860 LEU 860 860 860 LEU LEU A . n 
A 1 861 GLN 861 861 861 GLN GLN A . n 
A 1 862 LEU 862 862 862 LEU LEU A . n 
A 1 863 GLN 863 863 863 GLN GLN A . n 
A 1 864 ALA 864 864 864 ALA ALA A . n 
A 1 865 LEU 865 865 865 LEU LEU A . n 
A 1 866 PRO 866 866 866 PRO PRO A . n 
A 1 867 LEU 867 867 867 LEU LEU A . n 
A 1 868 SER 868 868 868 SER SER A . n 
A 1 869 TYR 869 869 869 TYR TYR A . n 
A 1 870 PHE 870 870 870 PHE PHE A . n 
A 1 871 PRO 871 871 871 PRO PRO A . n 
A 1 872 TRP 872 872 872 TRP TRP A . n 
A 1 873 LEU 873 873 873 LEU LEU A . n 
A 1 874 VAL 874 874 874 VAL VAL A . n 
A 1 875 ALA 875 875 875 ALA ALA A . n 
A 1 876 ILE 876 876 876 ILE ILE A . n 
A 1 877 LEU 877 877 877 LEU LEU A . n 
A 1 878 ALA 878 878 878 ALA ALA A . n 
A 1 879 GLY 879 879 879 GLY GLY A . n 
A 1 880 TYR 880 880 880 TYR TYR A . n 
A 1 881 MET 881 881 881 MET MET A . n 
A 1 882 THR 882 882 882 THR THR A . n 
A 1 883 LEU 883 883 883 LEU LEU A . n 
A 1 884 THR 884 884 884 THR THR A . n 
A 1 885 GLN 885 885 885 GLN GLN A . n 
A 1 886 LEU 886 886 886 LEU LEU A . n 
A 1 887 VAL 887 887 887 VAL VAL A . n 
A 1 888 LYS 888 888 888 LYS LYS A . n 
A 1 889 GLY 889 889 889 GLY GLY A . n 
A 1 890 PHE 890 890 890 PHE PHE A . n 
A 1 891 TYR 891 891 891 TYR TYR A . n 
A 1 892 SER 892 892 892 SER SER A . n 
A 1 893 ARG 893 893 893 ARG ARG A . n 
A 1 894 ARG 894 894 894 ARG ARG A . n 
A 1 895 TYR 895 895 895 TYR TYR A . n 
A 1 896 GLY 896 896 896 GLY GLY A . n 
A 1 897 TRP 897 897 897 TRP TRP A . n 
A 1 898 GLN 898 898 898 GLN GLN A . n 
A 1 899 HIS 899 899 ?   ?   ?   A . n 
A 1 900 HIS 900 900 ?   ?   ?   A . n 
A 1 901 HIS 901 901 ?   ?   ?   A . n 
A 1 902 HIS 902 902 ?   ?   ?   A . n 
A 1 903 HIS 903 903 ?   ?   ?   A . n 
A 1 904 HIS 904 904 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   PHE 2   2   2   PHE PHE B . n 
B 1 3   LYS 3   3   3   LYS LYS B . n 
B 1 4   GLU 4   4   4   GLU GLU B . n 
B 1 5   ILE 5   5   5   ILE ILE B . n 
B 1 6   PHE 6   6   6   PHE PHE B . n 
B 1 7   THR 7   7   7   THR THR B . n 
B 1 8   ARG 8   8   8   ARG ARG B . n 
B 1 9   LEU 9   9   9   LEU LEU B . n 
B 1 10  ILE 10  10  10  ILE ILE B . n 
B 1 11  ARG 11  11  11  ARG ARG B . n 
B 1 12  HIS 12  12  12  HIS HIS B . n 
B 1 13  LEU 13  13  13  LEU LEU B . n 
B 1 14  PRO 14  14  14  PRO PRO B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  ARG 16  16  16  ARG ARG B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  ARG 20  20  20  ARG ARG B . n 
B 1 21  ASP 21  21  21  ASP ASP B . n 
B 1 22  PRO 22  22  22  PRO PRO B . n 
B 1 23  LEU 23  23  23  LEU LEU B . n 
B 1 24  PRO 24  24  24  PRO PRO B . n 
B 1 25  GLY 25  25  25  GLY GLY B . n 
B 1 26  ALA 26  26  26  ALA ALA B . n 
B 1 27  GLN 27  27  27  GLN GLN B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  THR 29  29  29  THR THR B . n 
B 1 30  VAL 30  30  30  VAL VAL B . n 
B 1 31  ASN 31  31  31  ASN ASN B . n 
B 1 32  THR 32  32  32  THR THR B . n 
B 1 33  VAL 33  33  33  VAL VAL B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  PRO 35  35  35  PRO PRO B . n 
B 1 36  PRO 36  36  36  PRO PRO B . n 
B 1 37  SER 37  37  37  SER SER B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  SER 39  39  39  SER SER B . n 
B 1 40  ALA 40  40  40  ALA ALA B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  CYS 42  42  42  CYS CYS B . n 
B 1 43  LEU 43  43  43  LEU LEU B . n 
B 1 44  LYS 44  44  44  LYS LYS B . n 
B 1 45  MET 45  45  45  MET MET B . n 
B 1 46  ALA 46  46  46  ALA ALA B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  MET 48  48  48  MET MET B . n 
B 1 49  PRO 49  49  49  PRO PRO B . n 
B 1 50  GLU 50  50  50  GLU GLU B . n 
B 1 51  GLU 51  51  51  GLU GLU B . n 
B 1 52  GLU 52  52  52  GLU GLU B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  TRP 54  54  54  TRP TRP B . n 
B 1 55  LYS 55  55  55  LYS LYS B . n 
B 1 56  THR 56  56  56  THR THR B . n 
B 1 57  PHE 57  57  57  PHE PHE B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  HIS 60  60  60  HIS HIS B . n 
B 1 61  PRO 61  61  61  PRO PRO B . n 
B 1 62  GLU 62  62  62  GLU GLU B . n 
B 1 63  GLY 63  63  63  GLY GLY B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  GLN 66  66  66  GLN GLN B . n 
B 1 67  ALA 67  67  67  ALA ALA B . n 
B 1 68  GLU 68  68  68  GLU GLU B . n 
B 1 69  VAL 69  69  69  VAL VAL B . n 
B 1 70  GLU 70  70  70  GLU GLU B . n 
B 1 71  SER 71  71  71  SER SER B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  ARG 73  73  73  ARG ARG B . n 
B 1 74  GLU 74  74  74  GLU GLU B . n 
B 1 75  GLN 75  75  75  GLN GLN B . n 
B 1 76  HIS 76  76  76  HIS HIS B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  GLU 78  78  78  GLU GLU B . n 
B 1 79  ASN 79  79  79  ASN ASN B . n 
B 1 80  LYS 80  80  80  LYS LYS B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  PRO 82  82  82  PRO PRO B . n 
B 1 83  ALA 83  83  83  ALA ALA B . n 
B 1 84  GLN 84  84  84  GLN GLN B . n 
B 1 85  GLN 85  85  85  GLN GLN B . n 
B 1 86  PRO 86  86  86  PRO PRO B . n 
B 1 87  SER 87  87  87  SER SER B . n 
B 1 88  PRO 88  88  88  PRO PRO B . n 
B 1 89  TRP 89  89  89  TRP TRP B . n 
B 1 90  TRP 90  90  90  TRP TRP B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  HIS 92  92  92  HIS HIS B . n 
B 1 93  LEU 93  93  93  LEU LEU B . n 
B 1 94  TRP 94  94  94  TRP TRP B . n 
B 1 95  VAL 95  95  95  VAL VAL B . n 
B 1 96  CYS 96  96  96  CYS CYS B . n 
B 1 97  TYR 97  97  97  TYR TYR B . n 
B 1 98  ARG 98  98  98  ARG ARG B . n 
B 1 99  ASN 99  99  99  ASN ASN B . n 
B 1 100 PRO 100 100 100 PRO PRO B . n 
B 1 101 PHE 101 101 101 PHE PHE B . n 
B 1 102 ASN 102 102 102 ASN ASN B . n 
B 1 103 ILE 103 103 103 ILE ILE B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 THR 106 106 106 THR THR B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 LEU 108 108 108 LEU LEU B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 ALA 110 110 110 ALA ALA B . n 
B 1 111 ILE 111 111 111 ILE ILE B . n 
B 1 112 SER 112 112 112 SER SER B . n 
B 1 113 TYR 113 113 113 TYR TYR B . n 
B 1 114 ALA 114 114 114 ALA ALA B . n 
B 1 115 THR 115 115 115 THR THR B . n 
B 1 116 GLU 116 116 116 GLU GLU B . n 
B 1 117 ASP 117 117 117 ASP ASP B . n 
B 1 118 LEU 118 118 118 LEU LEU B . n 
B 1 119 PHE 119 119 119 PHE PHE B . n 
B 1 120 ALA 120 120 120 ALA ALA B . n 
B 1 121 ALA 121 121 121 ALA ALA B . n 
B 1 122 GLY 122 122 122 GLY GLY B . n 
B 1 123 VAL 123 123 123 VAL VAL B . n 
B 1 124 ILE 124 124 124 ILE ILE B . n 
B 1 125 ALA 125 125 125 ALA ALA B . n 
B 1 126 LEU 126 126 126 LEU LEU B . n 
B 1 127 MET 127 127 127 MET MET B . n 
B 1 128 VAL 128 128 128 VAL VAL B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 ILE 130 130 130 ILE ILE B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 THR 132 132 132 THR THR B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 ASN 135 135 135 ASN ASN B . n 
B 1 136 PHE 136 136 136 PHE PHE B . n 
B 1 137 ILE 137 137 137 ILE ILE B . n 
B 1 138 GLN 138 138 138 GLN GLN B . n 
B 1 139 GLU 139 139 139 GLU GLU B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 ARG 141 141 141 ARG ARG B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 LYS 144 144 144 LYS LYS B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 ALA 146 146 146 ALA ALA B . n 
B 1 147 ASP 147 147 147 ASP ASP B . n 
B 1 148 ALA 148 148 148 ALA ALA B . n 
B 1 149 LEU 149 149 149 LEU LEU B . n 
B 1 150 LYS 150 150 150 LYS LYS B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 MET 152 152 152 MET MET B . n 
B 1 153 VAL 153 153 153 VAL VAL B . n 
B 1 154 SER 154 154 154 SER SER B . n 
B 1 155 ASN 155 155 155 ASN ASN B . n 
B 1 156 THR 156 156 156 THR THR B . n 
B 1 157 ALA 157 157 157 ALA ALA B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 VAL 159 159 159 VAL VAL B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 ARG 161 161 161 ARG ARG B . n 
B 1 162 VAL 162 162 162 VAL VAL B . n 
B 1 163 ILE 163 163 163 ILE ILE B . n 
B 1 164 ASN 164 164 164 ASN ASN B . n 
B 1 165 ASP 165 165 165 ASP ASP B . n 
B 1 166 LYS 166 166 166 LYS LYS B . n 
B 1 167 GLY 167 167 167 GLY GLY B . n 
B 1 168 GLU 168 168 168 GLU GLU B . n 
B 1 169 ASN 169 169 169 ASN ASN B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 TRP 171 171 171 TRP TRP B . n 
B 1 172 LEU 172 172 172 LEU LEU B . n 
B 1 173 GLU 173 173 173 GLU GLU B . n 
B 1 174 ILE 174 174 174 ILE ILE B . n 
B 1 175 PRO 175 175 175 PRO PRO B . n 
B 1 176 ILE 176 176 176 ILE ILE B . n 
B 1 177 ASP 177 177 177 ASP ASP B . n 
B 1 178 GLN 178 178 178 GLN GLN B . n 
B 1 179 LEU 179 179 179 LEU LEU B . n 
B 1 180 VAL 180 180 180 VAL VAL B . n 
B 1 181 PRO 181 181 181 PRO PRO B . n 
B 1 182 GLY 182 182 182 GLY GLY B . n 
B 1 183 ASP 183 183 183 ASP ASP B . n 
B 1 184 ILE 184 184 184 ILE ILE B . n 
B 1 185 ILE 185 185 185 ILE ILE B . n 
B 1 186 LYS 186 186 186 LYS LYS B . n 
B 1 187 LEU 187 187 187 LEU LEU B . n 
B 1 188 ALA 188 188 188 ALA ALA B . n 
B 1 189 ALA 189 189 189 ALA ALA B . n 
B 1 190 GLY 190 190 190 GLY GLY B . n 
B 1 191 ASP 191 191 191 ASP ASP B . n 
B 1 192 MET 192 192 192 MET MET B . n 
B 1 193 ILE 193 193 193 ILE ILE B . n 
B 1 194 PRO 194 194 194 PRO PRO B . n 
B 1 195 ALA 195 195 195 ALA ALA B . n 
B 1 196 ASP 196 196 196 ASP ASP B . n 
B 1 197 LEU 197 197 197 LEU LEU B . n 
B 1 198 ARG 198 198 198 ARG ARG B . n 
B 1 199 ILE 199 199 199 ILE ILE B . n 
B 1 200 LEU 200 200 200 LEU LEU B . n 
B 1 201 GLN 201 201 201 GLN GLN B . n 
B 1 202 ALA 202 202 202 ALA ALA B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 ASP 204 204 204 ASP ASP B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 PHE 206 206 206 PHE PHE B . n 
B 1 207 VAL 207 207 207 VAL VAL B . n 
B 1 208 ALA 208 208 208 ALA ALA B . n 
B 1 209 GLN 209 209 209 GLN GLN B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 SER 211 211 211 SER SER B . n 
B 1 212 LEU 212 212 212 LEU LEU B . n 
B 1 213 THR 213 213 213 THR THR B . n 
B 1 214 GLY 214 214 214 GLY GLY B . n 
B 1 215 GLU 215 215 215 GLU GLU B . n 
B 1 216 SER 216 216 216 SER SER B . n 
B 1 217 LEU 217 217 217 LEU LEU B . n 
B 1 218 PRO 218 218 218 PRO PRO B . n 
B 1 219 VAL 219 219 219 VAL VAL B . n 
B 1 220 GLU 220 220 220 GLU GLU B . n 
B 1 221 LYS 221 221 221 LYS LYS B . n 
B 1 222 ALA 222 222 222 ALA ALA B . n 
B 1 223 ALA 223 223 223 ALA ALA B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 ARG 226 226 226 ARG ARG B . n 
B 1 227 GLN 227 227 227 GLN GLN B . n 
B 1 228 PRO 228 228 228 PRO PRO B . n 
B 1 229 GLU 229 229 229 GLU GLU B . n 
B 1 230 HIS 230 230 230 HIS HIS B . n 
B 1 231 SER 231 231 231 SER SER B . n 
B 1 232 ASN 232 232 232 ASN ASN B . n 
B 1 233 PRO 233 233 233 PRO PRO B . n 
B 1 234 LEU 234 234 234 LEU LEU B . n 
B 1 235 GLU 235 235 235 GLU GLU B . n 
B 1 236 CYS 236 236 236 CYS CYS B . n 
B 1 237 ASP 237 237 237 ASP ASP B . n 
B 1 238 THR 238 238 238 THR THR B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 CYS 240 240 240 CYS CYS B . n 
B 1 241 PHE 241 241 241 PHE PHE B . n 
B 1 242 MET 242 242 242 MET MET B . n 
B 1 243 GLY 243 243 243 GLY GLY B . n 
B 1 244 THR 244 244 244 THR THR B . n 
B 1 245 THR 245 245 245 THR THR B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 SER 248 248 248 SER SER B . n 
B 1 249 GLY 249 249 249 GLY GLY B . n 
B 1 250 THR 250 250 250 THR THR B . n 
B 1 251 ALA 251 251 251 ALA ALA B . n 
B 1 252 GLN 252 252 252 GLN GLN B . n 
B 1 253 ALA 253 253 253 ALA ALA B . n 
B 1 254 MET 254 254 254 MET MET B . n 
B 1 255 VAL 255 255 255 VAL VAL B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 ALA 257 257 257 ALA ALA B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 GLY 259 259 259 GLY GLY B . n 
B 1 260 ALA 260 260 260 ALA ALA B . n 
B 1 261 ASN 261 261 261 ASN ASN B . n 
B 1 262 THR 262 262 262 THR THR B . n 
B 1 263 TRP 263 263 263 TRP TRP B . n 
B 1 264 PHE 264 264 264 PHE PHE B . n 
B 1 265 GLY 265 265 265 GLY GLY B . n 
B 1 266 GLN 266 266 266 GLN GLN B . n 
B 1 267 LEU 267 267 267 LEU LEU B . n 
B 1 268 ALA 268 268 268 ALA ALA B . n 
B 1 269 GLY 269 269 269 GLY GLY B . n 
B 1 270 ARG 270 270 270 ARG ARG B . n 
B 1 271 VAL 271 271 271 VAL VAL B . n 
B 1 272 SER 272 272 272 SER SER B . n 
B 1 273 GLU 273 273 273 GLU GLU B . n 
B 1 274 GLN 274 274 274 GLN GLN B . n 
B 1 275 GLU 275 275 275 GLU GLU B . n 
B 1 276 SER 276 276 276 SER SER B . n 
B 1 277 GLU 277 277 277 GLU GLU B . n 
B 1 278 PRO 278 278 278 PRO PRO B . n 
B 1 279 ASN 279 279 279 ASN ASN B . n 
B 1 280 ALA 280 280 280 ALA ALA B . n 
B 1 281 PHE 281 281 281 PHE PHE B . n 
B 1 282 GLN 282 282 282 GLN GLN B . n 
B 1 283 GLN 283 283 283 GLN GLN B . n 
B 1 284 GLY 284 284 284 GLY GLY B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 SER 286 286 286 SER SER B . n 
B 1 287 ARG 287 287 287 ARG ARG B . n 
B 1 288 VAL 288 288 288 VAL VAL B . n 
B 1 289 SER 289 289 289 SER SER B . n 
B 1 290 MET 290 290 290 MET MET B . n 
B 1 291 LEU 291 291 291 LEU LEU B . n 
B 1 292 LEU 292 292 292 LEU LEU B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 ARG 294 294 294 ARG ARG B . n 
B 1 295 PHE 295 295 295 PHE PHE B . n 
B 1 296 MET 296 296 296 MET MET B . n 
B 1 297 LEU 297 297 297 LEU LEU B . n 
B 1 298 VAL 298 298 298 VAL VAL B . n 
B 1 299 MET 299 299 299 MET MET B . n 
B 1 300 ALA 300 300 300 ALA ALA B . n 
B 1 301 PRO 301 301 301 PRO PRO B . n 
B 1 302 VAL 302 302 302 VAL VAL B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 LEU 304 304 304 LEU LEU B . n 
B 1 305 LEU 305 305 305 LEU LEU B . n 
B 1 306 ILE 306 306 306 ILE ILE B . n 
B 1 307 ASN 307 307 307 ASN ASN B . n 
B 1 308 GLY 308 308 308 GLY GLY B . n 
B 1 309 TYR 309 309 309 TYR TYR B . n 
B 1 310 THR 310 310 310 THR THR B . n 
B 1 311 LYS 311 311 311 LYS LYS B . n 
B 1 312 GLY 312 312 312 GLY GLY B . n 
B 1 313 ASP 313 313 313 ASP ASP B . n 
B 1 314 TRP 314 314 314 TRP TRP B . n 
B 1 315 TRP 315 315 315 TRP TRP B . n 
B 1 316 GLU 316 316 316 GLU GLU B . n 
B 1 317 ALA 317 317 317 ALA ALA B . n 
B 1 318 ALA 318 318 318 ALA ALA B . n 
B 1 319 LEU 319 319 319 LEU LEU B . n 
B 1 320 PHE 320 320 320 PHE PHE B . n 
B 1 321 ALA 321 321 321 ALA ALA B . n 
B 1 322 LEU 322 322 322 LEU LEU B . n 
B 1 323 SER 323 323 323 SER SER B . n 
B 1 324 VAL 324 324 324 VAL VAL B . n 
B 1 325 ALA 325 325 325 ALA ALA B . n 
B 1 326 VAL 326 326 326 VAL VAL B . n 
B 1 327 GLY 327 327 327 GLY GLY B . n 
B 1 328 LEU 328 328 328 LEU LEU B . n 
B 1 329 THR 329 329 329 THR THR B . n 
B 1 330 PRO 330 330 330 PRO PRO B . n 
B 1 331 GLU 331 331 331 GLU GLU B . n 
B 1 332 MET 332 332 332 MET MET B . n 
B 1 333 LEU 333 333 333 LEU LEU B . n 
B 1 334 PRO 334 334 334 PRO PRO B . n 
B 1 335 MET 335 335 335 MET MET B . n 
B 1 336 ILE 336 336 336 ILE ILE B . n 
B 1 337 VAL 337 337 337 VAL VAL B . n 
B 1 338 THR 338 338 338 THR THR B . n 
B 1 339 SER 339 339 339 SER SER B . n 
B 1 340 THR 340 340 340 THR THR B . n 
B 1 341 LEU 341 341 341 LEU LEU B . n 
B 1 342 ALA 342 342 342 ALA ALA B . n 
B 1 343 ARG 343 343 343 ARG ARG B . n 
B 1 344 GLY 344 344 344 GLY GLY B . n 
B 1 345 ALA 345 345 345 ALA ALA B . n 
B 1 346 VAL 346 346 346 VAL VAL B . n 
B 1 347 LYS 347 347 347 LYS LYS B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 SER 349 349 349 SER SER B . n 
B 1 350 LYS 350 350 350 LYS LYS B . n 
B 1 351 GLN 351 351 351 GLN GLN B . n 
B 1 352 LYS 352 352 352 LYS LYS B . n 
B 1 353 VAL 353 353 353 VAL VAL B . n 
B 1 354 ILE 354 354 354 ILE ILE B . n 
B 1 355 VAL 355 355 355 VAL VAL B . n 
B 1 356 LYS 356 356 356 LYS LYS B . n 
B 1 357 HIS 357 357 357 HIS HIS B . n 
B 1 358 LEU 358 358 358 LEU LEU B . n 
B 1 359 ASP 359 359 359 ASP ASP B . n 
B 1 360 ALA 360 360 360 ALA ALA B . n 
B 1 361 ILE 361 361 361 ILE ILE B . n 
B 1 362 GLN 362 362 362 GLN GLN B . n 
B 1 363 ASN 363 363 363 ASN ASN B . n 
B 1 364 PHE 364 364 364 PHE PHE B . n 
B 1 365 GLY 365 365 365 GLY GLY B . n 
B 1 366 ALA 366 366 366 ALA ALA B . n 
B 1 367 MET 367 367 367 MET MET B . n 
B 1 368 ASP 368 368 368 ASP ASP B . n 
B 1 369 ILE 369 369 369 ILE ILE B . n 
B 1 370 LEU 370 370 370 LEU LEU B . n 
B 1 371 CYS 371 371 371 CYS CYS B . n 
B 1 372 THR 372 372 372 THR THR B . n 
B 1 373 ASP 373 373 373 ASP ASP B . n 
B 1 374 LYS 374 374 374 LYS LYS B . n 
B 1 375 THR 375 375 375 THR THR B . n 
B 1 376 GLY 376 376 376 GLY GLY B . n 
B 1 377 THR 377 377 377 THR THR B . n 
B 1 378 LEU 378 378 378 LEU LEU B . n 
B 1 379 THR 379 379 379 THR THR B . n 
B 1 380 GLN 380 380 380 GLN GLN B . n 
B 1 381 ASP 381 381 381 ASP ASP B . n 
B 1 382 LYS 382 382 382 LYS LYS B . n 
B 1 383 ILE 383 383 383 ILE ILE B . n 
B 1 384 VAL 384 384 384 VAL VAL B . n 
B 1 385 LEU 385 385 385 LEU LEU B . n 
B 1 386 GLU 386 386 386 GLU GLU B . n 
B 1 387 ASN 387 387 387 ASN ASN B . n 
B 1 388 HIS 388 388 388 HIS HIS B . n 
B 1 389 THR 389 389 389 THR THR B . n 
B 1 390 ASP 390 390 390 ASP ASP B . n 
B 1 391 ILE 391 391 391 ILE ILE B . n 
B 1 392 SER 392 392 392 SER SER B . n 
B 1 393 GLY 393 393 393 GLY GLY B . n 
B 1 394 LYS 394 394 394 LYS LYS B . n 
B 1 395 THR 395 395 395 THR THR B . n 
B 1 396 SER 396 396 396 SER SER B . n 
B 1 397 GLU 397 397 397 GLU GLU B . n 
B 1 398 ARG 398 398 398 ARG ARG B . n 
B 1 399 VAL 399 399 399 VAL VAL B . n 
B 1 400 LEU 400 400 400 LEU LEU B . n 
B 1 401 HIS 401 401 401 HIS HIS B . n 
B 1 402 SER 402 402 402 SER SER B . n 
B 1 403 ALA 403 403 403 ALA ALA B . n 
B 1 404 TRP 404 404 404 TRP TRP B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 ASN 406 406 406 ASN ASN B . n 
B 1 407 SER 407 407 407 SER SER B . n 
B 1 408 HIS 408 408 408 HIS HIS B . n 
B 1 409 TYR 409 409 409 TYR TYR B . n 
B 1 410 GLN 410 410 410 GLN GLN B . n 
B 1 411 THR 411 411 411 THR THR B . n 
B 1 412 GLY 412 412 412 GLY GLY B . n 
B 1 413 LEU 413 413 413 LEU LEU B . n 
B 1 414 LYS 414 414 414 LYS LYS B . n 
B 1 415 ASN 415 415 415 ASN ASN B . n 
B 1 416 LEU 416 416 416 LEU LEU B . n 
B 1 417 LEU 417 417 417 LEU LEU B . n 
B 1 418 ASP 418 418 418 ASP ASP B . n 
B 1 419 THR 419 419 419 THR THR B . n 
B 1 420 ALA 420 420 420 ALA ALA B . n 
B 1 421 VAL 421 421 421 VAL VAL B . n 
B 1 422 LEU 422 422 422 LEU LEU B . n 
B 1 423 GLU 423 423 423 GLU GLU B . n 
B 1 424 GLY 424 424 424 GLY GLY B . n 
B 1 425 THR 425 425 425 THR THR B . n 
B 1 426 ASP 426 426 426 ASP ASP B . n 
B 1 427 GLU 427 427 427 GLU GLU B . n 
B 1 428 GLU 428 428 428 GLU GLU B . n 
B 1 429 SER 429 429 429 SER SER B . n 
B 1 430 ALA 430 430 430 ALA ALA B . n 
B 1 431 ARG 431 431 431 ARG ARG B . n 
B 1 432 SER 432 432 432 SER SER B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 SER 435 435 435 SER SER B . n 
B 1 436 ARG 436 436 436 ARG ARG B . n 
B 1 437 TRP 437 437 437 TRP TRP B . n 
B 1 438 GLN 438 438 438 GLN GLN B . n 
B 1 439 LYS 439 439 439 LYS LYS B . n 
B 1 440 ILE 440 440 440 ILE ILE B . n 
B 1 441 ASP 441 441 441 ASP ASP B . n 
B 1 442 GLU 442 442 442 GLU GLU B . n 
B 1 443 ILE 443 443 443 ILE ILE B . n 
B 1 444 PRO 444 444 444 PRO PRO B . n 
B 1 445 PHE 445 445 445 PHE PHE B . n 
B 1 446 ASP 446 446 446 ASP ASP B . n 
B 1 447 PHE 447 447 447 PHE PHE B . n 
B 1 448 GLU 448 448 448 GLU GLU B . n 
B 1 449 ARG 449 449 449 ARG ARG B . n 
B 1 450 ARG 450 450 450 ARG ARG B . n 
B 1 451 ARG 451 451 451 ARG ARG B . n 
B 1 452 MET 452 452 452 MET MET B . n 
B 1 453 SER 453 453 453 SER SER B . n 
B 1 454 VAL 454 454 454 VAL VAL B . n 
B 1 455 VAL 455 455 455 VAL VAL B . n 
B 1 456 VAL 456 456 456 VAL VAL B . n 
B 1 457 ALA 457 457 457 ALA ALA B . n 
B 1 458 GLU 458 458 458 GLU GLU B . n 
B 1 459 ASN 459 459 459 ASN ASN B . n 
B 1 460 THR 460 460 460 THR THR B . n 
B 1 461 GLU 461 461 461 GLU GLU B . n 
B 1 462 HIS 462 462 462 HIS HIS B . n 
B 1 463 HIS 463 463 463 HIS HIS B . n 
B 1 464 GLN 464 464 464 GLN GLN B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 VAL 466 466 466 VAL VAL B . n 
B 1 467 CYS 467 467 467 CYS CYS B . n 
B 1 468 LYS 468 468 468 LYS LYS B . n 
B 1 469 GLY 469 469 469 GLY GLY B . n 
B 1 470 ALA 470 470 470 ALA ALA B . n 
B 1 471 LEU 471 471 471 LEU LEU B . n 
B 1 472 GLN 472 472 472 GLN GLN B . n 
B 1 473 GLU 473 473 473 GLU GLU B . n 
B 1 474 ILE 474 474 474 ILE ILE B . n 
B 1 475 LEU 475 475 475 LEU LEU B . n 
B 1 476 ASN 476 476 476 ASN ASN B . n 
B 1 477 VAL 477 477 477 VAL VAL B . n 
B 1 478 CYS 478 478 478 CYS CYS B . n 
B 1 479 SER 479 479 479 SER SER B . n 
B 1 480 GLN 480 480 480 GLN GLN B . n 
B 1 481 VAL 481 481 481 VAL VAL B . n 
B 1 482 ARG 482 482 482 ARG ARG B . n 
B 1 483 HIS 483 483 483 HIS HIS B . n 
B 1 484 ASN 484 484 484 ASN ASN B . n 
B 1 485 GLY 485 485 485 GLY GLY B . n 
B 1 486 GLU 486 486 486 GLU GLU B . n 
B 1 487 ILE 487 487 487 ILE ILE B . n 
B 1 488 VAL 488 488 488 VAL VAL B . n 
B 1 489 PRO 489 489 489 PRO PRO B . n 
B 1 490 LEU 490 490 490 LEU LEU B . n 
B 1 491 ASP 491 491 491 ASP ASP B . n 
B 1 492 ASP 492 492 492 ASP ASP B . n 
B 1 493 ILE 493 493 493 ILE ILE B . n 
B 1 494 MET 494 494 494 MET MET B . n 
B 1 495 LEU 495 495 495 LEU LEU B . n 
B 1 496 ARG 496 496 496 ARG ARG B . n 
B 1 497 LYS 497 497 497 LYS LYS B . n 
B 1 498 ILE 498 498 498 ILE ILE B . n 
B 1 499 LYS 499 499 499 LYS LYS B . n 
B 1 500 ARG 500 500 500 ARG ARG B . n 
B 1 501 VAL 501 501 501 VAL VAL B . n 
B 1 502 THR 502 502 502 THR THR B . n 
B 1 503 ASP 503 503 503 ASP ASP B . n 
B 1 504 THR 504 504 504 THR THR B . n 
B 1 505 LEU 505 505 505 LEU LEU B . n 
B 1 506 ASN 506 506 506 ASN ASN B . n 
B 1 507 ARG 507 507 507 ARG ARG B . n 
B 1 508 GLN 508 508 508 GLN GLN B . n 
B 1 509 GLY 509 509 509 GLY GLY B . n 
B 1 510 LEU 510 510 510 LEU LEU B . n 
B 1 511 ARG 511 511 511 ARG ARG B . n 
B 1 512 VAL 512 512 512 VAL VAL B . n 
B 1 513 VAL 513 513 513 VAL VAL B . n 
B 1 514 ALA 514 514 514 ALA ALA B . n 
B 1 515 VAL 515 515 515 VAL VAL B . n 
B 1 516 ALA 516 516 516 ALA ALA B . n 
B 1 517 THR 517 517 517 THR THR B . n 
B 1 518 LYS 518 518 518 LYS LYS B . n 
B 1 519 TYR 519 519 519 TYR TYR B . n 
B 1 520 LEU 520 520 520 LEU LEU B . n 
B 1 521 PRO 521 521 521 PRO PRO B . n 
B 1 522 ALA 522 522 522 ALA ALA B . n 
B 1 523 ARG 523 523 523 ARG ARG B . n 
B 1 524 GLU 524 524 524 GLU GLU B . n 
B 1 525 GLY 525 525 525 GLY GLY B . n 
B 1 526 ASP 526 526 526 ASP ASP B . n 
B 1 527 TYR 527 527 527 TYR TYR B . n 
B 1 528 GLN 528 528 528 GLN GLN B . n 
B 1 529 ARG 529 529 529 ARG ARG B . n 
B 1 530 ALA 530 530 530 ALA ALA B . n 
B 1 531 ASP 531 531 531 ASP ASP B . n 
B 1 532 GLU 532 532 532 GLU GLU B . n 
B 1 533 SER 533 533 533 SER SER B . n 
B 1 534 ASP 534 534 534 ASP ASP B . n 
B 1 535 LEU 535 535 535 LEU LEU B . n 
B 1 536 ILE 536 536 536 ILE ILE B . n 
B 1 537 LEU 537 537 537 LEU LEU B . n 
B 1 538 GLU 538 538 538 GLU GLU B . n 
B 1 539 GLY 539 539 539 GLY GLY B . n 
B 1 540 TYR 540 540 540 TYR TYR B . n 
B 1 541 ILE 541 541 541 ILE ILE B . n 
B 1 542 ALA 542 542 542 ALA ALA B . n 
B 1 543 PHE 543 543 543 PHE PHE B . n 
B 1 544 LEU 544 544 544 LEU LEU B . n 
B 1 545 ASP 545 545 545 ASP ASP B . n 
B 1 546 PRO 546 546 546 PRO PRO B . n 
B 1 547 PRO 547 547 547 PRO PRO B . n 
B 1 548 LYS 548 548 548 LYS LYS B . n 
B 1 549 GLU 549 549 549 GLU GLU B . n 
B 1 550 THR 550 550 550 THR THR B . n 
B 1 551 THR 551 551 551 THR THR B . n 
B 1 552 ALA 552 552 552 ALA ALA B . n 
B 1 553 PRO 553 553 553 PRO PRO B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 LEU 555 555 555 LEU LEU B . n 
B 1 556 LYS 556 556 556 LYS LYS B . n 
B 1 557 ALA 557 557 557 ALA ALA B . n 
B 1 558 LEU 558 558 558 LEU LEU B . n 
B 1 559 LYS 559 559 559 LYS LYS B . n 
B 1 560 ALA 560 560 560 ALA ALA B . n 
B 1 561 SER 561 561 561 SER SER B . n 
B 1 562 GLY 562 562 562 GLY GLY B . n 
B 1 563 ILE 563 563 563 ILE ILE B . n 
B 1 564 THR 564 564 564 THR THR B . n 
B 1 565 VAL 565 565 565 VAL VAL B . n 
B 1 566 LYS 566 566 566 LYS LYS B . n 
B 1 567 ILE 567 567 567 ILE ILE B . n 
B 1 568 LEU 568 568 568 LEU LEU B . n 
B 1 569 THR 569 569 569 THR THR B . n 
B 1 570 GLY 570 570 570 GLY GLY B . n 
B 1 571 ASP 571 571 571 ASP ASP B . n 
B 1 572 SER 572 572 572 SER SER B . n 
B 1 573 GLU 573 573 573 GLU GLU B . n 
B 1 574 LEU 574 574 574 LEU LEU B . n 
B 1 575 VAL 575 575 575 VAL VAL B . n 
B 1 576 ALA 576 576 576 ALA ALA B . n 
B 1 577 ALA 577 577 577 ALA ALA B . n 
B 1 578 LYS 578 578 578 LYS LYS B . n 
B 1 579 VAL 579 579 579 VAL VAL B . n 
B 1 580 CYS 580 580 580 CYS CYS B . n 
B 1 581 HIS 581 581 581 HIS HIS B . n 
B 1 582 GLU 582 582 582 GLU GLU B . n 
B 1 583 VAL 583 583 583 VAL VAL B . n 
B 1 584 GLY 584 584 584 GLY GLY B . n 
B 1 585 LEU 585 585 585 LEU LEU B . n 
B 1 586 ASP 586 586 586 ASP ASP B . n 
B 1 587 ALA 587 587 587 ALA ALA B . n 
B 1 588 GLY 588 588 588 GLY GLY B . n 
B 1 589 GLU 589 589 589 GLU GLU B . n 
B 1 590 VAL 590 590 590 VAL VAL B . n 
B 1 591 VAL 591 591 591 VAL VAL B . n 
B 1 592 ILE 592 592 592 ILE ILE B . n 
B 1 593 GLY 593 593 593 GLY GLY B . n 
B 1 594 SER 594 594 594 SER SER B . n 
B 1 595 ASP 595 595 595 ASP ASP B . n 
B 1 596 ILE 596 596 596 ILE ILE B . n 
B 1 597 GLU 597 597 597 GLU GLU B . n 
B 1 598 THR 598 598 598 THR THR B . n 
B 1 599 LEU 599 599 599 LEU LEU B . n 
B 1 600 SER 600 600 600 SER SER B . n 
B 1 601 ASP 601 601 601 ASP ASP B . n 
B 1 602 ASP 602 602 602 ASP ASP B . n 
B 1 603 GLU 603 603 603 GLU GLU B . n 
B 1 604 LEU 604 604 604 LEU LEU B . n 
B 1 605 ALA 605 605 605 ALA ALA B . n 
B 1 606 ASN 606 606 606 ASN ASN B . n 
B 1 607 LEU 607 607 607 LEU LEU B . n 
B 1 608 ALA 608 608 608 ALA ALA B . n 
B 1 609 GLN 609 609 609 GLN GLN B . n 
B 1 610 ARG 610 610 610 ARG ARG B . n 
B 1 611 THR 611 611 611 THR THR B . n 
B 1 612 THR 612 612 612 THR THR B . n 
B 1 613 LEU 613 613 613 LEU LEU B . n 
B 1 614 PHE 614 614 614 PHE PHE B . n 
B 1 615 ALA 615 615 615 ALA ALA B . n 
B 1 616 ARG 616 616 616 ARG ARG B . n 
B 1 617 LEU 617 617 617 LEU LEU B . n 
B 1 618 THR 618 618 618 THR THR B . n 
B 1 619 PRO 619 619 619 PRO PRO B . n 
B 1 620 MET 620 620 620 MET MET B . n 
B 1 621 HIS 621 621 621 HIS HIS B . n 
B 1 622 LYS 622 622 622 LYS LYS B . n 
B 1 623 GLU 623 623 623 GLU GLU B . n 
B 1 624 ARG 624 624 624 ARG ARG B . n 
B 1 625 ILE 625 625 625 ILE ILE B . n 
B 1 626 VAL 626 626 626 VAL VAL B . n 
B 1 627 THR 627 627 627 THR THR B . n 
B 1 628 LEU 628 628 628 LEU LEU B . n 
B 1 629 LEU 629 629 629 LEU LEU B . n 
B 1 630 LYS 630 630 630 LYS LYS B . n 
B 1 631 ARG 631 631 631 ARG ARG B . n 
B 1 632 GLU 632 632 632 GLU GLU B . n 
B 1 633 GLY 633 633 633 GLY GLY B . n 
B 1 634 HIS 634 634 634 HIS HIS B . n 
B 1 635 VAL 635 635 635 VAL VAL B . n 
B 1 636 VAL 636 636 636 VAL VAL B . n 
B 1 637 GLY 637 637 637 GLY GLY B . n 
B 1 638 PHE 638 638 638 PHE PHE B . n 
B 1 639 MET 639 639 639 MET MET B . n 
B 1 640 GLY 640 640 640 GLY GLY B . n 
B 1 641 ASP 641 641 641 ASP ASP B . n 
B 1 642 GLY 642 642 642 GLY GLY B . n 
B 1 643 ILE 643 643 643 ILE ILE B . n 
B 1 644 ASN 644 644 644 ASN ASN B . n 
B 1 645 ASP 645 645 645 ASP ASP B . n 
B 1 646 ALA 646 646 646 ALA ALA B . n 
B 1 647 PRO 647 647 647 PRO PRO B . n 
B 1 648 ALA 648 648 648 ALA ALA B . n 
B 1 649 LEU 649 649 649 LEU LEU B . n 
B 1 650 ARG 650 650 650 ARG ARG B . n 
B 1 651 ALA 651 651 651 ALA ALA B . n 
B 1 652 ALA 652 652 652 ALA ALA B . n 
B 1 653 ASP 653 653 653 ASP ASP B . n 
B 1 654 ILE 654 654 654 ILE ILE B . n 
B 1 655 GLY 655 655 655 GLY GLY B . n 
B 1 656 ILE 656 656 656 ILE ILE B . n 
B 1 657 SER 657 657 657 SER SER B . n 
B 1 658 VAL 658 658 658 VAL VAL B . n 
B 1 659 ASP 659 659 659 ASP ASP B . n 
B 1 660 GLY 660 660 660 GLY GLY B . n 
B 1 661 ALA 661 661 661 ALA ALA B . n 
B 1 662 VAL 662 662 662 VAL VAL B . n 
B 1 663 ASP 663 663 663 ASP ASP B . n 
B 1 664 ILE 664 664 664 ILE ILE B . n 
B 1 665 ALA 665 665 665 ALA ALA B . n 
B 1 666 ARG 666 666 666 ARG ARG B . n 
B 1 667 GLU 667 667 667 GLU GLU B . n 
B 1 668 ALA 668 668 668 ALA ALA B . n 
B 1 669 ALA 669 669 669 ALA ALA B . n 
B 1 670 ASP 670 670 670 ASP ASP B . n 
B 1 671 ILE 671 671 671 ILE ILE B . n 
B 1 672 ILE 672 672 672 ILE ILE B . n 
B 1 673 LEU 673 673 673 LEU LEU B . n 
B 1 674 LEU 674 674 674 LEU LEU B . n 
B 1 675 GLU 675 675 675 GLU GLU B . n 
B 1 676 LYS 676 676 676 LYS LYS B . n 
B 1 677 SER 677 677 677 SER SER B . n 
B 1 678 LEU 678 678 678 LEU LEU B . n 
B 1 679 MET 679 679 679 MET MET B . n 
B 1 680 VAL 680 680 680 VAL VAL B . n 
B 1 681 LEU 681 681 681 LEU LEU B . n 
B 1 682 GLU 682 682 682 GLU GLU B . n 
B 1 683 GLU 683 683 683 GLU GLU B . n 
B 1 684 GLY 684 684 684 GLY GLY B . n 
B 1 685 VAL 685 685 685 VAL VAL B . n 
B 1 686 ILE 686 686 686 ILE ILE B . n 
B 1 687 GLU 687 687 687 GLU GLU B . n 
B 1 688 GLY 688 688 688 GLY GLY B . n 
B 1 689 ARG 689 689 689 ARG ARG B . n 
B 1 690 ARG 690 690 690 ARG ARG B . n 
B 1 691 THR 691 691 691 THR THR B . n 
B 1 692 PHE 692 692 692 PHE PHE B . n 
B 1 693 ALA 693 693 693 ALA ALA B . n 
B 1 694 ASN 694 694 694 ASN ASN B . n 
B 1 695 MET 695 695 695 MET MET B . n 
B 1 696 LEU 696 696 696 LEU LEU B . n 
B 1 697 LYS 697 697 697 LYS LYS B . n 
B 1 698 TYR 698 698 698 TYR TYR B . n 
B 1 699 ILE 699 699 699 ILE ILE B . n 
B 1 700 LYS 700 700 700 LYS LYS B . n 
B 1 701 MET 701 701 701 MET MET B . n 
B 1 702 THR 702 702 702 THR THR B . n 
B 1 703 ALA 703 703 703 ALA ALA B . n 
B 1 704 SER 704 704 704 SER SER B . n 
B 1 705 SER 705 705 705 SER SER B . n 
B 1 706 ASN 706 706 706 ASN ASN B . n 
B 1 707 PHE 707 707 707 PHE PHE B . n 
B 1 708 GLY 708 708 708 GLY GLY B . n 
B 1 709 ASN 709 709 709 ASN ASN B . n 
B 1 710 VAL 710 710 710 VAL VAL B . n 
B 1 711 PHE 711 711 711 PHE PHE B . n 
B 1 712 SER 712 712 712 SER SER B . n 
B 1 713 VAL 713 713 713 VAL VAL B . n 
B 1 714 LEU 714 714 714 LEU LEU B . n 
B 1 715 VAL 715 715 715 VAL VAL B . n 
B 1 716 ALA 716 716 716 ALA ALA B . n 
B 1 717 SER 717 717 717 SER SER B . n 
B 1 718 ALA 718 718 718 ALA ALA B . n 
B 1 719 PHE 719 719 719 PHE PHE B . n 
B 1 720 LEU 720 720 720 LEU LEU B . n 
B 1 721 PRO 721 721 721 PRO PRO B . n 
B 1 722 PHE 722 722 722 PHE PHE B . n 
B 1 723 LEU 723 723 723 LEU LEU B . n 
B 1 724 PRO 724 724 724 PRO PRO B . n 
B 1 725 MET 725 725 725 MET MET B . n 
B 1 726 LEU 726 726 726 LEU LEU B . n 
B 1 727 PRO 727 727 727 PRO PRO B . n 
B 1 728 LEU 728 728 728 LEU LEU B . n 
B 1 729 HIS 729 729 729 HIS HIS B . n 
B 1 730 LEU 730 730 730 LEU LEU B . n 
B 1 731 LEU 731 731 731 LEU LEU B . n 
B 1 732 ILE 732 732 732 ILE ILE B . n 
B 1 733 GLN 733 733 733 GLN GLN B . n 
B 1 734 ASN 734 734 734 ASN ASN B . n 
B 1 735 LEU 735 735 735 LEU LEU B . n 
B 1 736 LEU 736 736 736 LEU LEU B . n 
B 1 737 TYR 737 737 737 TYR TYR B . n 
B 1 738 ASP 738 738 738 ASP ASP B . n 
B 1 739 VAL 739 739 739 VAL VAL B . n 
B 1 740 SER 740 740 740 SER SER B . n 
B 1 741 GLN 741 741 741 GLN GLN B . n 
B 1 742 VAL 742 742 742 VAL VAL B . n 
B 1 743 ALA 743 743 743 ALA ALA B . n 
B 1 744 ILE 744 744 744 ILE ILE B . n 
B 1 745 PRO 745 745 745 PRO PRO B . n 
B 1 746 PHE 746 746 746 PHE PHE B . n 
B 1 747 ASP 747 747 747 ASP ASP B . n 
B 1 748 ASN 748 748 748 ASN ASN B . n 
B 1 749 VAL 749 749 749 VAL VAL B . n 
B 1 750 ASP 750 750 750 ASP ASP B . n 
B 1 751 ASP 751 751 751 ASP ASP B . n 
B 1 752 GLU 752 752 752 GLU GLU B . n 
B 1 753 GLN 753 753 753 GLN GLN B . n 
B 1 754 ILE 754 754 754 ILE ILE B . n 
B 1 755 GLN 755 755 755 GLN GLN B . n 
B 1 756 LYS 756 756 756 LYS LYS B . n 
B 1 757 PRO 757 757 757 PRO PRO B . n 
B 1 758 GLN 758 758 758 GLN GLN B . n 
B 1 759 ARG 759 759 759 ARG ARG B . n 
B 1 760 TRP 760 760 760 TRP TRP B . n 
B 1 761 ASN 761 761 761 ASN ASN B . n 
B 1 762 PRO 762 762 762 PRO PRO B . n 
B 1 763 ALA 763 763 763 ALA ALA B . n 
B 1 764 ASP 764 764 764 ASP ASP B . n 
B 1 765 LEU 765 765 765 LEU LEU B . n 
B 1 766 GLY 766 766 766 GLY GLY B . n 
B 1 767 ARG 767 767 767 ARG ARG B . n 
B 1 768 PHE 768 768 768 PHE PHE B . n 
B 1 769 MET 769 769 769 MET MET B . n 
B 1 770 ILE 770 770 770 ILE ILE B . n 
B 1 771 PHE 771 771 771 PHE PHE B . n 
B 1 772 PHE 772 772 772 PHE PHE B . n 
B 1 773 GLY 773 773 773 GLY GLY B . n 
B 1 774 PRO 774 774 774 PRO PRO B . n 
B 1 775 ILE 775 775 775 ILE ILE B . n 
B 1 776 SER 776 776 776 SER SER B . n 
B 1 777 SER 777 777 777 SER SER B . n 
B 1 778 ILE 778 778 778 ILE ILE B . n 
B 1 779 PHE 779 779 779 PHE PHE B . n 
B 1 780 ASP 780 780 780 ASP ASP B . n 
B 1 781 ILE 781 781 781 ILE ILE B . n 
B 1 782 LEU 782 782 782 LEU LEU B . n 
B 1 783 THR 783 783 783 THR THR B . n 
B 1 784 PHE 784 784 784 PHE PHE B . n 
B 1 785 CYS 785 785 785 CYS CYS B . n 
B 1 786 LEU 786 786 786 LEU LEU B . n 
B 1 787 MET 787 787 787 MET MET B . n 
B 1 788 TRP 788 788 788 TRP TRP B . n 
B 1 789 TRP 789 789 789 TRP TRP B . n 
B 1 790 VAL 790 790 790 VAL VAL B . n 
B 1 791 PHE 791 791 791 PHE PHE B . n 
B 1 792 HIS 792 792 792 HIS HIS B . n 
B 1 793 ALA 793 793 793 ALA ALA B . n 
B 1 794 ASN 794 794 794 ASN ASN B . n 
B 1 795 THR 795 795 795 THR THR B . n 
B 1 796 PRO 796 796 796 PRO PRO B . n 
B 1 797 GLU 797 797 797 GLU GLU B . n 
B 1 798 THR 798 798 798 THR THR B . n 
B 1 799 GLN 799 799 799 GLN GLN B . n 
B 1 800 THR 800 800 800 THR THR B . n 
B 1 801 LEU 801 801 801 LEU LEU B . n 
B 1 802 PHE 802 802 802 PHE PHE B . n 
B 1 803 GLN 803 803 803 GLN GLN B . n 
B 1 804 SER 804 804 804 SER SER B . n 
B 1 805 GLY 805 805 805 GLY GLY B . n 
B 1 806 TRP 806 806 806 TRP TRP B . n 
B 1 807 PHE 807 807 807 PHE PHE B . n 
B 1 808 VAL 808 808 808 VAL VAL B . n 
B 1 809 VAL 809 809 809 VAL VAL B . n 
B 1 810 GLY 810 810 810 GLY GLY B . n 
B 1 811 LEU 811 811 811 LEU LEU B . n 
B 1 812 LEU 812 812 812 LEU LEU B . n 
B 1 813 SER 813 813 813 SER SER B . n 
B 1 814 GLN 814 814 814 GLN GLN B . n 
B 1 815 THR 815 815 815 THR THR B . n 
B 1 816 LEU 816 816 816 LEU LEU B . n 
B 1 817 ILE 817 817 817 ILE ILE B . n 
B 1 818 VAL 818 818 818 VAL VAL B . n 
B 1 819 HIS 819 819 819 HIS HIS B . n 
B 1 820 MET 820 820 820 MET MET B . n 
B 1 821 ILE 821 821 821 ILE ILE B . n 
B 1 822 ARG 822 822 822 ARG ARG B . n 
B 1 823 THR 823 823 823 THR THR B . n 
B 1 824 ARG 824 824 824 ARG ARG B . n 
B 1 825 ARG 825 825 825 ARG ARG B . n 
B 1 826 VAL 826 826 826 VAL VAL B . n 
B 1 827 PRO 827 827 827 PRO PRO B . n 
B 1 828 PHE 828 828 828 PHE PHE B . n 
B 1 829 ILE 829 829 829 ILE ILE B . n 
B 1 830 GLN 830 830 830 GLN GLN B . n 
B 1 831 SER 831 831 831 SER SER B . n 
B 1 832 CYS 832 832 832 CYS CYS B . n 
B 1 833 ALA 833 833 833 ALA ALA B . n 
B 1 834 SER 834 834 834 SER SER B . n 
B 1 835 TRP 835 835 835 TRP TRP B . n 
B 1 836 PRO 836 836 836 PRO PRO B . n 
B 1 837 LEU 837 837 837 LEU LEU B . n 
B 1 838 MET 838 838 838 MET MET B . n 
B 1 839 ILE 839 839 839 ILE ILE B . n 
B 1 840 MET 840 840 840 MET MET B . n 
B 1 841 THR 841 841 841 THR THR B . n 
B 1 842 VAL 842 842 842 VAL VAL B . n 
B 1 843 ILE 843 843 843 ILE ILE B . n 
B 1 844 VAL 844 844 844 VAL VAL B . n 
B 1 845 MET 845 845 845 MET MET B . n 
B 1 846 ILE 846 846 846 ILE ILE B . n 
B 1 847 VAL 847 847 847 VAL VAL B . n 
B 1 848 GLY 848 848 848 GLY GLY B . n 
B 1 849 ILE 849 849 849 ILE ILE B . n 
B 1 850 ALA 850 850 850 ALA ALA B . n 
B 1 851 LEU 851 851 851 LEU LEU B . n 
B 1 852 PRO 852 852 852 PRO PRO B . n 
B 1 853 PHE 853 853 853 PHE PHE B . n 
B 1 854 SER 854 854 854 SER SER B . n 
B 1 855 PRO 855 855 855 PRO PRO B . n 
B 1 856 LEU 856 856 856 LEU LEU B . n 
B 1 857 ALA 857 857 857 ALA ALA B . n 
B 1 858 SER 858 858 858 SER SER B . n 
B 1 859 TYR 859 859 859 TYR TYR B . n 
B 1 860 LEU 860 860 860 LEU LEU B . n 
B 1 861 GLN 861 861 861 GLN GLN B . n 
B 1 862 LEU 862 862 862 LEU LEU B . n 
B 1 863 GLN 863 863 863 GLN GLN B . n 
B 1 864 ALA 864 864 864 ALA ALA B . n 
B 1 865 LEU 865 865 865 LEU LEU B . n 
B 1 866 PRO 866 866 866 PRO PRO B . n 
B 1 867 LEU 867 867 867 LEU LEU B . n 
B 1 868 SER 868 868 868 SER SER B . n 
B 1 869 TYR 869 869 869 TYR TYR B . n 
B 1 870 PHE 870 870 870 PHE PHE B . n 
B 1 871 PRO 871 871 871 PRO PRO B . n 
B 1 872 TRP 872 872 872 TRP TRP B . n 
B 1 873 LEU 873 873 873 LEU LEU B . n 
B 1 874 VAL 874 874 874 VAL VAL B . n 
B 1 875 ALA 875 875 875 ALA ALA B . n 
B 1 876 ILE 876 876 876 ILE ILE B . n 
B 1 877 LEU 877 877 877 LEU LEU B . n 
B 1 878 ALA 878 878 878 ALA ALA B . n 
B 1 879 GLY 879 879 879 GLY GLY B . n 
B 1 880 TYR 880 880 880 TYR TYR B . n 
B 1 881 MET 881 881 881 MET MET B . n 
B 1 882 THR 882 882 882 THR THR B . n 
B 1 883 LEU 883 883 883 LEU LEU B . n 
B 1 884 THR 884 884 884 THR THR B . n 
B 1 885 GLN 885 885 885 GLN GLN B . n 
B 1 886 LEU 886 886 886 LEU LEU B . n 
B 1 887 VAL 887 887 887 VAL VAL B . n 
B 1 888 LYS 888 888 888 LYS LYS B . n 
B 1 889 GLY 889 889 889 GLY GLY B . n 
B 1 890 PHE 890 890 890 PHE PHE B . n 
B 1 891 TYR 891 891 891 TYR TYR B . n 
B 1 892 SER 892 892 892 SER SER B . n 
B 1 893 ARG 893 893 893 ARG ARG B . n 
B 1 894 ARG 894 894 894 ARG ARG B . n 
B 1 895 TYR 895 895 895 TYR TYR B . n 
B 1 896 GLY 896 896 896 GLY GLY B . n 
B 1 897 TRP 897 897 897 TRP TRP B . n 
B 1 898 GLN 898 898 898 GLN GLN B . n 
B 1 899 HIS 899 899 ?   ?   ?   B . n 
B 1 900 HIS 900 900 ?   ?   ?   B . n 
B 1 901 HIS 901 901 ?   ?   ?   B . n 
B 1 902 HIS 902 902 ?   ?   ?   B . n 
B 1 903 HIS 903 903 ?   ?   ?   B . n 
B 1 904 HIS 904 904 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        MG 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   MG 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 MG 1 1001 1001 MG MG A . 
D 2 MG 1 1002 1002 MG MG A . 
E 2 MG 1 1003 1003 MG MG A . 
F 2 MG 1 1001 1001 MG MG B . 
G 2 MG 1 1002 1002 MG MG B . 
H 2 MG 1 1003 1003 MG MG B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A MET 1   ? CG  ? A MET 1   CG  
2   1 Y 1 A MET 1   ? SD  ? A MET 1   SD  
3   1 Y 1 A MET 1   ? CE  ? A MET 1   CE  
4   1 Y 1 A PHE 2   ? CG  ? A PHE 2   CG  
5   1 Y 1 A PHE 2   ? CD1 ? A PHE 2   CD1 
6   1 Y 1 A PHE 2   ? CD2 ? A PHE 2   CD2 
7   1 Y 1 A PHE 2   ? CE1 ? A PHE 2   CE1 
8   1 Y 1 A PHE 2   ? CE2 ? A PHE 2   CE2 
9   1 Y 1 A PHE 2   ? CZ  ? A PHE 2   CZ  
10  1 Y 1 A LYS 3   ? CG  ? A LYS 3   CG  
11  1 Y 1 A LYS 3   ? CD  ? A LYS 3   CD  
12  1 Y 1 A LYS 3   ? CE  ? A LYS 3   CE  
13  1 Y 1 A LYS 3   ? NZ  ? A LYS 3   NZ  
14  1 Y 1 A GLU 4   ? CG  ? A GLU 4   CG  
15  1 Y 1 A GLU 4   ? CD  ? A GLU 4   CD  
16  1 Y 1 A GLU 4   ? OE1 ? A GLU 4   OE1 
17  1 Y 1 A GLU 4   ? OE2 ? A GLU 4   OE2 
18  1 Y 1 A ILE 5   ? CG1 ? A ILE 5   CG1 
19  1 Y 1 A ILE 5   ? CG2 ? A ILE 5   CG2 
20  1 Y 1 A ILE 5   ? CD1 ? A ILE 5   CD1 
21  1 Y 1 A PHE 6   ? CG  ? A PHE 6   CG  
22  1 Y 1 A PHE 6   ? CD1 ? A PHE 6   CD1 
23  1 Y 1 A PHE 6   ? CD2 ? A PHE 6   CD2 
24  1 Y 1 A PHE 6   ? CE1 ? A PHE 6   CE1 
25  1 Y 1 A PHE 6   ? CE2 ? A PHE 6   CE2 
26  1 Y 1 A PHE 6   ? CZ  ? A PHE 6   CZ  
27  1 Y 1 A GLN 27  ? CG  ? A GLN 27  CG  
28  1 Y 1 A GLN 27  ? CD  ? A GLN 27  CD  
29  1 Y 1 A GLN 27  ? OE1 ? A GLN 27  OE1 
30  1 Y 1 A GLN 27  ? NE2 ? A GLN 27  NE2 
31  1 Y 1 A GLN 28  ? CG  ? A GLN 28  CG  
32  1 Y 1 A GLN 28  ? CD  ? A GLN 28  CD  
33  1 Y 1 A GLN 28  ? OE1 ? A GLN 28  OE1 
34  1 Y 1 A GLN 28  ? NE2 ? A GLN 28  NE2 
35  1 Y 1 A THR 29  ? OG1 ? A THR 29  OG1 
36  1 Y 1 A THR 29  ? CG2 ? A THR 29  CG2 
37  1 Y 1 A VAL 30  ? CG1 ? A VAL 30  CG1 
38  1 Y 1 A VAL 30  ? CG2 ? A VAL 30  CG2 
39  1 Y 1 A ASN 31  ? CG  ? A ASN 31  CG  
40  1 Y 1 A ASN 31  ? OD1 ? A ASN 31  OD1 
41  1 Y 1 A ASN 31  ? ND2 ? A ASN 31  ND2 
42  1 Y 1 A THR 32  ? OG1 ? A THR 32  OG1 
43  1 Y 1 A THR 32  ? CG2 ? A THR 32  CG2 
44  1 Y 1 A VAL 33  ? CG1 ? A VAL 33  CG1 
45  1 Y 1 A VAL 33  ? CG2 ? A VAL 33  CG2 
46  1 Y 1 A VAL 34  ? CG1 ? A VAL 34  CG1 
47  1 Y 1 A VAL 34  ? CG2 ? A VAL 34  CG2 
48  1 Y 1 A GLN 66  ? CG  ? A GLN 66  CG  
49  1 Y 1 A GLN 66  ? CD  ? A GLN 66  CD  
50  1 Y 1 A GLN 66  ? OE1 ? A GLN 66  OE1 
51  1 Y 1 A GLN 66  ? NE2 ? A GLN 66  NE2 
52  1 Y 1 A LYS 166 ? CG  ? A LYS 166 CG  
53  1 Y 1 A LYS 166 ? CD  ? A LYS 166 CD  
54  1 Y 1 A LYS 166 ? CE  ? A LYS 166 CE  
55  1 Y 1 A LYS 166 ? NZ  ? A LYS 166 NZ  
56  1 Y 1 A GLU 168 ? CG  ? A GLU 168 CG  
57  1 Y 1 A GLU 168 ? CD  ? A GLU 168 CD  
58  1 Y 1 A GLU 168 ? OE1 ? A GLU 168 OE1 
59  1 Y 1 A GLU 168 ? OE2 ? A GLU 168 OE2 
60  1 Y 1 A LEU 267 ? CG  ? A LEU 267 CG  
61  1 Y 1 A LEU 267 ? CD1 ? A LEU 267 CD1 
62  1 Y 1 A LEU 267 ? CD2 ? A LEU 267 CD2 
63  1 Y 1 A ARG 270 ? CG  ? A ARG 270 CG  
64  1 Y 1 A ARG 270 ? CD  ? A ARG 270 CD  
65  1 Y 1 A ARG 270 ? NE  ? A ARG 270 NE  
66  1 Y 1 A ARG 270 ? CZ  ? A ARG 270 CZ  
67  1 Y 1 A ARG 270 ? NH1 ? A ARG 270 NH1 
68  1 Y 1 A ARG 270 ? NH2 ? A ARG 270 NH2 
69  1 Y 1 A VAL 271 ? CG1 ? A VAL 271 CG1 
70  1 Y 1 A VAL 271 ? CG2 ? A VAL 271 CG2 
71  1 Y 1 A SER 272 ? OG  ? A SER 272 OG  
72  1 Y 1 A GLU 273 ? CG  ? A GLU 273 CG  
73  1 Y 1 A GLU 273 ? CD  ? A GLU 273 CD  
74  1 Y 1 A GLU 273 ? OE1 ? A GLU 273 OE1 
75  1 Y 1 A GLU 273 ? OE2 ? A GLU 273 OE2 
76  1 Y 1 A GLN 274 ? CG  ? A GLN 274 CG  
77  1 Y 1 A GLN 274 ? CD  ? A GLN 274 CD  
78  1 Y 1 A GLN 274 ? OE1 ? A GLN 274 OE1 
79  1 Y 1 A GLN 274 ? NE2 ? A GLN 274 NE2 
80  1 Y 1 A GLU 275 ? CG  ? A GLU 275 CG  
81  1 Y 1 A GLU 275 ? CD  ? A GLU 275 CD  
82  1 Y 1 A GLU 275 ? OE1 ? A GLU 275 OE1 
83  1 Y 1 A GLU 275 ? OE2 ? A GLU 275 OE2 
84  1 Y 1 A SER 276 ? OG  ? A SER 276 OG  
85  1 Y 1 A GLN 898 ? CG  ? A GLN 898 CG  
86  1 Y 1 A GLN 898 ? CD  ? A GLN 898 CD  
87  1 Y 1 A GLN 898 ? OE1 ? A GLN 898 OE1 
88  1 Y 1 A GLN 898 ? NE2 ? A GLN 898 NE2 
89  1 Y 1 B MET 1   ? CG  ? B MET 1   CG  
90  1 Y 1 B MET 1   ? SD  ? B MET 1   SD  
91  1 Y 1 B MET 1   ? CE  ? B MET 1   CE  
92  1 Y 1 B PHE 2   ? CG  ? B PHE 2   CG  
93  1 Y 1 B PHE 2   ? CD1 ? B PHE 2   CD1 
94  1 Y 1 B PHE 2   ? CD2 ? B PHE 2   CD2 
95  1 Y 1 B PHE 2   ? CE1 ? B PHE 2   CE1 
96  1 Y 1 B PHE 2   ? CE2 ? B PHE 2   CE2 
97  1 Y 1 B PHE 2   ? CZ  ? B PHE 2   CZ  
98  1 Y 1 B LYS 3   ? CG  ? B LYS 3   CG  
99  1 Y 1 B LYS 3   ? CD  ? B LYS 3   CD  
100 1 Y 1 B LYS 3   ? CE  ? B LYS 3   CE  
101 1 Y 1 B LYS 3   ? NZ  ? B LYS 3   NZ  
102 1 Y 1 B GLU 4   ? CG  ? B GLU 4   CG  
103 1 Y 1 B GLU 4   ? CD  ? B GLU 4   CD  
104 1 Y 1 B GLU 4   ? OE1 ? B GLU 4   OE1 
105 1 Y 1 B GLU 4   ? OE2 ? B GLU 4   OE2 
106 1 Y 1 B ILE 5   ? CG1 ? B ILE 5   CG1 
107 1 Y 1 B ILE 5   ? CG2 ? B ILE 5   CG2 
108 1 Y 1 B ILE 5   ? CD1 ? B ILE 5   CD1 
109 1 Y 1 B PHE 6   ? CG  ? B PHE 6   CG  
110 1 Y 1 B PHE 6   ? CD1 ? B PHE 6   CD1 
111 1 Y 1 B PHE 6   ? CD2 ? B PHE 6   CD2 
112 1 Y 1 B PHE 6   ? CE1 ? B PHE 6   CE1 
113 1 Y 1 B PHE 6   ? CE2 ? B PHE 6   CE2 
114 1 Y 1 B PHE 6   ? CZ  ? B PHE 6   CZ  
115 1 Y 1 B GLN 27  ? CG  ? B GLN 27  CG  
116 1 Y 1 B GLN 27  ? CD  ? B GLN 27  CD  
117 1 Y 1 B GLN 27  ? OE1 ? B GLN 27  OE1 
118 1 Y 1 B GLN 27  ? NE2 ? B GLN 27  NE2 
119 1 Y 1 B GLN 28  ? CG  ? B GLN 28  CG  
120 1 Y 1 B GLN 28  ? CD  ? B GLN 28  CD  
121 1 Y 1 B GLN 28  ? OE1 ? B GLN 28  OE1 
122 1 Y 1 B GLN 28  ? NE2 ? B GLN 28  NE2 
123 1 Y 1 B THR 29  ? OG1 ? B THR 29  OG1 
124 1 Y 1 B THR 29  ? CG2 ? B THR 29  CG2 
125 1 Y 1 B VAL 30  ? CG1 ? B VAL 30  CG1 
126 1 Y 1 B VAL 30  ? CG2 ? B VAL 30  CG2 
127 1 Y 1 B ASN 31  ? CG  ? B ASN 31  CG  
128 1 Y 1 B ASN 31  ? OD1 ? B ASN 31  OD1 
129 1 Y 1 B ASN 31  ? ND2 ? B ASN 31  ND2 
130 1 Y 1 B THR 32  ? OG1 ? B THR 32  OG1 
131 1 Y 1 B THR 32  ? CG2 ? B THR 32  CG2 
132 1 Y 1 B VAL 33  ? CG1 ? B VAL 33  CG1 
133 1 Y 1 B VAL 33  ? CG2 ? B VAL 33  CG2 
134 1 Y 1 B VAL 34  ? CG1 ? B VAL 34  CG1 
135 1 Y 1 B VAL 34  ? CG2 ? B VAL 34  CG2 
136 1 Y 1 B GLN 66  ? CG  ? B GLN 66  CG  
137 1 Y 1 B GLN 66  ? CD  ? B GLN 66  CD  
138 1 Y 1 B GLN 66  ? OE1 ? B GLN 66  OE1 
139 1 Y 1 B GLN 66  ? NE2 ? B GLN 66  NE2 
140 1 Y 1 B LYS 166 ? CG  ? B LYS 166 CG  
141 1 Y 1 B LYS 166 ? CD  ? B LYS 166 CD  
142 1 Y 1 B LYS 166 ? CE  ? B LYS 166 CE  
143 1 Y 1 B LYS 166 ? NZ  ? B LYS 166 NZ  
144 1 Y 1 B GLU 168 ? CG  ? B GLU 168 CG  
145 1 Y 1 B GLU 168 ? CD  ? B GLU 168 CD  
146 1 Y 1 B GLU 168 ? OE1 ? B GLU 168 OE1 
147 1 Y 1 B GLU 168 ? OE2 ? B GLU 168 OE2 
148 1 Y 1 B LEU 267 ? CG  ? B LEU 267 CG  
149 1 Y 1 B LEU 267 ? CD1 ? B LEU 267 CD1 
150 1 Y 1 B LEU 267 ? CD2 ? B LEU 267 CD2 
151 1 Y 1 B ARG 270 ? CG  ? B ARG 270 CG  
152 1 Y 1 B ARG 270 ? CD  ? B ARG 270 CD  
153 1 Y 1 B ARG 270 ? NE  ? B ARG 270 NE  
154 1 Y 1 B ARG 270 ? CZ  ? B ARG 270 CZ  
155 1 Y 1 B ARG 270 ? NH1 ? B ARG 270 NH1 
156 1 Y 1 B ARG 270 ? NH2 ? B ARG 270 NH2 
157 1 Y 1 B VAL 271 ? CG1 ? B VAL 271 CG1 
158 1 Y 1 B VAL 271 ? CG2 ? B VAL 271 CG2 
159 1 Y 1 B SER 272 ? OG  ? B SER 272 OG  
160 1 Y 1 B GLU 273 ? CG  ? B GLU 273 CG  
161 1 Y 1 B GLU 273 ? CD  ? B GLU 273 CD  
162 1 Y 1 B GLU 273 ? OE1 ? B GLU 273 OE1 
163 1 Y 1 B GLU 273 ? OE2 ? B GLU 273 OE2 
164 1 Y 1 B GLN 274 ? CG  ? B GLN 274 CG  
165 1 Y 1 B GLN 274 ? CD  ? B GLN 274 CD  
166 1 Y 1 B GLN 274 ? OE1 ? B GLN 274 OE1 
167 1 Y 1 B GLN 274 ? NE2 ? B GLN 274 NE2 
168 1 Y 1 B GLU 275 ? CG  ? B GLU 275 CG  
169 1 Y 1 B GLU 275 ? CD  ? B GLU 275 CD  
170 1 Y 1 B GLU 275 ? OE1 ? B GLU 275 OE1 
171 1 Y 1 B GLU 275 ? OE2 ? B GLU 275 OE2 
172 1 Y 1 B SER 276 ? OG  ? B SER 276 OG  
173 1 Y 1 B GLN 898 ? CG  ? B GLN 898 CG  
174 1 Y 1 B GLN 898 ? CD  ? B GLN 898 CD  
175 1 Y 1 B GLN 898 ? OE1 ? B GLN 898 OE1 
176 1 Y 1 B GLN 898 ? NE2 ? B GLN 898 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UYC 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UYC 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UYC 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8UYC 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 14110 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.455 ? 19220 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 3.670 ? 1908  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039 ? 2276  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 2450  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8UYC 
_struct.title                        'Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ADP' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UYC 
_struct_keywords.text            
'magnesium, transport, membrane protein, dimer, oligomer, cryo-EM, P-type ATPase, ion translocation' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 2 ? 
H N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ATMA_ECOLI 
_struct_ref.pdbx_db_accession          P0ABB8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQ
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UYC A 1 ? 898 ? P0ABB8 1 ? 898 ? 1 898 
2 1 8UYC B 1 ? 898 ? P0ABB8 1 ? 898 ? 1 898 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UYC HIS A 899 ? UNP P0ABB8 ? ? 'expression tag' 899 1  
1 8UYC HIS A 900 ? UNP P0ABB8 ? ? 'expression tag' 900 2  
1 8UYC HIS A 901 ? UNP P0ABB8 ? ? 'expression tag' 901 3  
1 8UYC HIS A 902 ? UNP P0ABB8 ? ? 'expression tag' 902 4  
1 8UYC HIS A 903 ? UNP P0ABB8 ? ? 'expression tag' 903 5  
1 8UYC HIS A 904 ? UNP P0ABB8 ? ? 'expression tag' 904 6  
2 8UYC HIS B 899 ? UNP P0ABB8 ? ? 'expression tag' 899 7  
2 8UYC HIS B 900 ? UNP P0ABB8 ? ? 'expression tag' 900 8  
2 8UYC HIS B 901 ? UNP P0ABB8 ? ? 'expression tag' 901 9  
2 8UYC HIS B 902 ? UNP P0ABB8 ? ? 'expression tag' 902 10 
2 8UYC HIS B 903 ? UNP P0ABB8 ? ? 'expression tag' 903 11 
2 8UYC HIS B 904 ? UNP P0ABB8 ? ? 'expression tag' 904 12 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ILE A 5   ? ILE A 10  ? ILE A 5   ILE A 10  1 ? 6  
HELX_P HELX_P2  AA2 VAL A 30  ? VAL A 34  ? VAL A 30  VAL A 34  5 ? 5  
HELX_P HELX_P3  AA3 PRO A 35  ? VAL A 47  ? PRO A 35  VAL A 47  1 ? 13 
HELX_P HELX_P4  AA4 PRO A 49  ? PHE A 57  ? PRO A 49  PHE A 57  1 ? 9  
HELX_P HELX_P5  AA5 ASN A 65  ? GLY A 77  ? ASN A 65  GLY A 77  1 ? 13 
HELX_P HELX_P6  AA6 PRO A 88  ? ARG A 98  ? PRO A 88  ARG A 98  1 ? 11 
HELX_P HELX_P7  AA7 ASN A 99  ? TYR A 113 ? ASN A 99  TYR A 113 1 ? 15 
HELX_P HELX_P8  AA8 ALA A 120 ? VAL A 153 ? ALA A 120 VAL A 153 1 ? 34 
HELX_P HELX_P9  AA9 ASP A 177 ? LEU A 179 ? ASP A 177 LEU A 179 5 ? 3  
HELX_P HELX_P10 AB1 ASN A 232 ? CYS A 236 ? ASN A 232 CYS A 236 5 ? 5  
HELX_P HELX_P11 AB2 THR A 258 ? ASN A 261 ? THR A 258 ASN A 261 5 ? 4  
HELX_P HELX_P12 AB3 THR A 262 ? LEU A 267 ? THR A 262 LEU A 267 1 ? 6  
HELX_P HELX_P13 AB4 ASN A 279 ? LYS A 311 ? ASN A 279 LYS A 311 1 ? 33 
HELX_P HELX_P14 AB5 ASP A 313 ? GLY A 327 ? ASP A 313 GLY A 327 1 ? 15 
HELX_P HELX_P15 AB6 LEU A 328 ? GLU A 331 ? LEU A 328 GLU A 331 5 ? 4  
HELX_P HELX_P16 AB7 MET A 332 ? LYS A 350 ? MET A 332 LYS A 350 1 ? 19 
HELX_P HELX_P17 AB8 LEU A 358 ? MET A 367 ? LEU A 358 MET A 367 1 ? 10 
HELX_P HELX_P18 AB9 ASP A 373 ? LEU A 378 ? ASP A 373 LEU A 378 1 ? 6  
HELX_P HELX_P19 AC1 SER A 396 ? TYR A 409 ? SER A 396 TYR A 409 1 ? 14 
HELX_P HELX_P20 AC2 ASN A 415 ? THR A 425 ? ASN A 415 THR A 425 1 ? 11 
HELX_P HELX_P21 AC3 ASP A 426 ? TRP A 437 ? ASP A 426 TRP A 437 1 ? 12 
HELX_P HELX_P22 AC4 LEU A 471 ? VAL A 477 ? LEU A 471 VAL A 477 1 ? 7  
HELX_P HELX_P23 AC5 ASP A 491 ? GLN A 508 ? ASP A 491 GLN A 508 1 ? 18 
HELX_P HELX_P24 AC6 GLN A 528 ? GLU A 532 ? GLN A 528 GLU A 532 5 ? 5  
HELX_P HELX_P25 AC7 THR A 550 ? GLY A 562 ? THR A 550 GLY A 562 1 ? 13 
HELX_P HELX_P26 AC8 SER A 572 ? GLY A 584 ? SER A 572 GLY A 584 1 ? 13 
HELX_P HELX_P27 AC9 SER A 594 ? ILE A 596 ? SER A 594 ILE A 596 5 ? 3  
HELX_P HELX_P28 AD1 SER A 600 ? ALA A 608 ? SER A 600 ALA A 608 1 ? 9  
HELX_P HELX_P29 AD2 THR A 618 ? LEU A 629 ? THR A 618 LEU A 629 1 ? 12 
HELX_P HELX_P30 AD3 GLY A 642 ? ASN A 644 ? GLY A 642 ASN A 644 5 ? 3  
HELX_P HELX_P31 AD4 ASP A 645 ? ALA A 652 ? ASP A 645 ALA A 652 1 ? 8  
HELX_P HELX_P32 AD5 VAL A 662 ? ALA A 668 ? VAL A 662 ALA A 668 1 ? 7  
HELX_P HELX_P33 AD6 SER A 677 ? SER A 717 ? SER A 677 SER A 717 1 ? 41 
HELX_P HELX_P34 AD7 LEU A 726 ? VAL A 742 ? LEU A 726 VAL A 742 1 ? 17 
HELX_P HELX_P35 AD8 ALA A 743 ? ASP A 747 ? ALA A 743 ASP A 747 5 ? 5  
HELX_P HELX_P36 AD9 PRO A 762 ? GLY A 773 ? PRO A 762 GLY A 773 1 ? 12 
HELX_P HELX_P37 AE1 GLY A 773 ? TRP A 789 ? GLY A 773 TRP A 789 1 ? 17 
HELX_P HELX_P38 AE2 THR A 795 ? GLU A 797 ? THR A 795 GLU A 797 5 ? 3  
HELX_P HELX_P39 AE3 THR A 798 ? ARG A 822 ? THR A 798 ARG A 822 1 ? 25 
HELX_P HELX_P40 AE4 SER A 834 ? SER A 854 ? SER A 834 SER A 854 1 ? 21 
HELX_P HELX_P41 AE5 PRO A 855 ? LEU A 860 ? PRO A 855 LEU A 860 1 ? 6  
HELX_P HELX_P42 AE6 SER A 868 ? TYR A 895 ? SER A 868 TYR A 895 1 ? 28 
HELX_P HELX_P43 AE7 ILE B 5   ? ILE B 10  ? ILE B 5   ILE B 10  1 ? 6  
HELX_P HELX_P44 AE8 VAL B 30  ? VAL B 34  ? VAL B 30  VAL B 34  5 ? 5  
HELX_P HELX_P45 AE9 PRO B 35  ? VAL B 47  ? PRO B 35  VAL B 47  1 ? 13 
HELX_P HELX_P46 AF1 PRO B 49  ? PHE B 57  ? PRO B 49  PHE B 57  1 ? 9  
HELX_P HELX_P47 AF2 ASN B 65  ? GLY B 77  ? ASN B 65  GLY B 77  1 ? 13 
HELX_P HELX_P48 AF3 PRO B 88  ? ARG B 98  ? PRO B 88  ARG B 98  1 ? 11 
HELX_P HELX_P49 AF4 ASN B 99  ? TYR B 113 ? ASN B 99  TYR B 113 1 ? 15 
HELX_P HELX_P50 AF5 ALA B 120 ? VAL B 153 ? ALA B 120 VAL B 153 1 ? 34 
HELX_P HELX_P51 AF6 ASP B 177 ? LEU B 179 ? ASP B 177 LEU B 179 5 ? 3  
HELX_P HELX_P52 AF7 ASN B 232 ? CYS B 236 ? ASN B 232 CYS B 236 5 ? 5  
HELX_P HELX_P53 AF8 THR B 258 ? ASN B 261 ? THR B 258 ASN B 261 5 ? 4  
HELX_P HELX_P54 AF9 THR B 262 ? LEU B 267 ? THR B 262 LEU B 267 1 ? 6  
HELX_P HELX_P55 AG1 ASN B 279 ? LYS B 311 ? ASN B 279 LYS B 311 1 ? 33 
HELX_P HELX_P56 AG2 ASP B 313 ? GLY B 327 ? ASP B 313 GLY B 327 1 ? 15 
HELX_P HELX_P57 AG3 LEU B 328 ? GLU B 331 ? LEU B 328 GLU B 331 5 ? 4  
HELX_P HELX_P58 AG4 MET B 332 ? LYS B 350 ? MET B 332 LYS B 350 1 ? 19 
HELX_P HELX_P59 AG5 LEU B 358 ? MET B 367 ? LEU B 358 MET B 367 1 ? 10 
HELX_P HELX_P60 AG6 ASP B 373 ? LEU B 378 ? ASP B 373 LEU B 378 1 ? 6  
HELX_P HELX_P61 AG7 SER B 396 ? TYR B 409 ? SER B 396 TYR B 409 1 ? 14 
HELX_P HELX_P62 AG8 ASN B 415 ? THR B 425 ? ASN B 415 THR B 425 1 ? 11 
HELX_P HELX_P63 AG9 ASP B 426 ? TRP B 437 ? ASP B 426 TRP B 437 1 ? 12 
HELX_P HELX_P64 AH1 LEU B 471 ? VAL B 477 ? LEU B 471 VAL B 477 1 ? 7  
HELX_P HELX_P65 AH2 ASP B 491 ? GLN B 508 ? ASP B 491 GLN B 508 1 ? 18 
HELX_P HELX_P66 AH3 GLN B 528 ? GLU B 532 ? GLN B 528 GLU B 532 5 ? 5  
HELX_P HELX_P67 AH4 THR B 550 ? GLY B 562 ? THR B 550 GLY B 562 1 ? 13 
HELX_P HELX_P68 AH5 SER B 572 ? GLY B 584 ? SER B 572 GLY B 584 1 ? 13 
HELX_P HELX_P69 AH6 SER B 594 ? ILE B 596 ? SER B 594 ILE B 596 5 ? 3  
HELX_P HELX_P70 AH7 SER B 600 ? ALA B 608 ? SER B 600 ALA B 608 1 ? 9  
HELX_P HELX_P71 AH8 THR B 618 ? LEU B 629 ? THR B 618 LEU B 629 1 ? 12 
HELX_P HELX_P72 AH9 GLY B 642 ? ASN B 644 ? GLY B 642 ASN B 644 5 ? 3  
HELX_P HELX_P73 AI1 ASP B 645 ? ALA B 652 ? ASP B 645 ALA B 652 1 ? 8  
HELX_P HELX_P74 AI2 VAL B 662 ? ALA B 668 ? VAL B 662 ALA B 668 1 ? 7  
HELX_P HELX_P75 AI3 SER B 677 ? SER B 717 ? SER B 677 SER B 717 1 ? 41 
HELX_P HELX_P76 AI4 LEU B 726 ? VAL B 742 ? LEU B 726 VAL B 742 1 ? 17 
HELX_P HELX_P77 AI5 ALA B 743 ? ASP B 747 ? ALA B 743 ASP B 747 5 ? 5  
HELX_P HELX_P78 AI6 PRO B 762 ? TRP B 789 ? PRO B 762 TRP B 789 1 ? 28 
HELX_P HELX_P79 AI7 THR B 795 ? GLU B 797 ? THR B 795 GLU B 797 5 ? 3  
HELX_P HELX_P80 AI8 THR B 798 ? ARG B 822 ? THR B 798 ARG B 822 1 ? 25 
HELX_P HELX_P81 AI9 SER B 834 ? SER B 854 ? SER B 834 SER B 854 1 ? 21 
HELX_P HELX_P82 AJ1 PRO B 855 ? LEU B 860 ? PRO B 855 LEU B 860 1 ? 6  
HELX_P HELX_P83 AJ2 SER B 868 ? TYR B 895 ? SER B 868 TYR B 895 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 191 OD1 ? ? ? 1_555 D MG . MG ? ? A ASP 191 A MG 1002 1_555 ? ? ? ? ? ? ? 2.158 ? ? 
metalc2  metalc ? ? A ASP 191 OD2 ? ? ? 1_555 D MG . MG ? ? A ASP 191 A MG 1002 1_555 ? ? ? ? ? ? ? 2.586 ? ? 
metalc3  metalc ? ? A ASP 441 OD1 ? ? ? 1_555 E MG . MG ? ? A ASP 441 A MG 1003 1_555 ? ? ? ? ? ? ? 2.158 ? ? 
metalc4  metalc ? ? A ASP 526 OD1 ? ? ? 1_555 E MG . MG ? ? A ASP 526 A MG 1003 1_555 ? ? ? ? ? ? ? 2.853 ? ? 
metalc5  metalc ? ? A ASP 526 OD2 ? ? ? 1_555 E MG . MG ? ? A ASP 526 A MG 1003 1_555 ? ? ? ? ? ? ? 2.824 ? ? 
metalc6  metalc ? ? A ASN 709 OD1 ? ? ? 1_555 C MG . MG ? ? A ASN 709 A MG 1001 1_555 ? ? ? ? ? ? ? 2.016 ? ? 
metalc7  metalc ? ? B ASP 191 OD1 ? ? ? 1_555 G MG . MG ? ? B ASP 191 B MG 1002 1_555 ? ? ? ? ? ? ? 2.157 ? ? 
metalc8  metalc ? ? B ASP 191 OD2 ? ? ? 1_555 G MG . MG ? ? B ASP 191 B MG 1002 1_555 ? ? ? ? ? ? ? 2.582 ? ? 
metalc9  metalc ? ? B ASP 441 OD1 ? ? ? 1_555 H MG . MG ? ? B ASP 441 B MG 1003 1_555 ? ? ? ? ? ? ? 2.158 ? ? 
metalc10 metalc ? ? B ASP 526 OD1 ? ? ? 1_555 H MG . MG ? ? B ASP 526 B MG 1003 1_555 ? ? ? ? ? ? ? 2.859 ? ? 
metalc11 metalc ? ? B ASP 526 OD2 ? ? ? 1_555 H MG . MG ? ? B ASP 526 B MG 1003 1_555 ? ? ? ? ? ? ? 2.820 ? ? 
metalc12 metalc ? ? B ASN 709 OD1 ? ? ? 1_555 F MG . MG ? ? B ASN 709 B MG 1001 1_555 ? ? ? ? ? ? ? 2.017 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD1 ? A ASP 191 ? A ASP 191 ? 1_555 MG ? D MG . ? A MG 1002 ? 1_555 OD2 ? A ASP 191 ? A ASP 191 ? 1_555 54.2  ? 
2 OD1 ? A ASP 441 ? A ASP 441 ? 1_555 MG ? E MG . ? A MG 1003 ? 1_555 OD1 ? A ASP 526 ? A ASP 526 ? 1_555 98.7  ? 
3 OD1 ? A ASP 441 ? A ASP 441 ? 1_555 MG ? E MG . ? A MG 1003 ? 1_555 OD2 ? A ASP 526 ? A ASP 526 ? 1_555 137.6 ? 
4 OD1 ? A ASP 526 ? A ASP 526 ? 1_555 MG ? E MG . ? A MG 1003 ? 1_555 OD2 ? A ASP 526 ? A ASP 526 ? 1_555 45.5  ? 
5 OD1 ? B ASP 191 ? B ASP 191 ? 1_555 MG ? G MG . ? B MG 1002 ? 1_555 OD2 ? B ASP 191 ? B ASP 191 ? 1_555 54.3  ? 
6 OD1 ? B ASP 441 ? B ASP 441 ? 1_555 MG ? H MG . ? B MG 1003 ? 1_555 OD1 ? B ASP 526 ? B ASP 526 ? 1_555 98.4  ? 
7 OD1 ? B ASP 441 ? B ASP 441 ? 1_555 MG ? H MG . ? B MG 1003 ? 1_555 OD2 ? B ASP 526 ? B ASP 526 ? 1_555 137.4 ? 
8 OD1 ? B ASP 526 ? B ASP 526 ? 1_555 MG ? H MG . ? B MG 1003 ? 1_555 OD2 ? B ASP 526 ? B ASP 526 ? 1_555 45.5  ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 6 ? 
AA3 ? 8 ? 
AA4 ? 6 ? 
AA5 ? 4 ? 
AA6 ? 6 ? 
AA7 ? 6 ? 
AA8 ? 8 ? 
AA9 ? 6 ? 
AB1 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? parallel      
AA3 4 5 ? parallel      
AA3 5 6 ? parallel      
AA3 6 7 ? parallel      
AA3 7 8 ? parallel      
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? parallel      
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA7 5 6 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA8 7 8 ? parallel      
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 172 ? PRO A 175 ? LEU A 172 PRO A 175 
AA1 2 THR A 156 ? VAL A 159 ? THR A 156 VAL A 159 
AA1 3 ILE A 184 ? LEU A 187 ? ILE A 184 LEU A 187 
AA1 4 THR A 245 ? VAL A 255 ? THR A 245 VAL A 255 
AA1 5 LEU A 197 ? ALA A 208 ? LEU A 197 ALA A 208 
AA1 6 VAL A 219 ? LYS A 221 ? VAL A 219 LYS A 221 
AA2 1 LEU A 172 ? PRO A 175 ? LEU A 172 PRO A 175 
AA2 2 THR A 156 ? VAL A 159 ? THR A 156 VAL A 159 
AA2 3 ILE A 184 ? LEU A 187 ? ILE A 184 LEU A 187 
AA2 4 THR A 245 ? VAL A 255 ? THR A 245 VAL A 255 
AA2 5 LEU A 197 ? ALA A 208 ? LEU A 197 ALA A 208 
AA2 6 LEU A 239 ? CYS A 240 ? LEU A 239 CYS A 240 
AA3 1 VAL A 353 ? VAL A 355 ? VAL A 353 VAL A 355 
AA3 2 ILE A 671 ? LEU A 673 ? ILE A 671 LEU A 673 
AA3 3 ILE A 654 ? VAL A 658 ? ILE A 654 VAL A 658 
AA3 4 VAL A 636 ? MET A 639 ? VAL A 636 MET A 639 
AA3 5 ILE A 369 ? THR A 372 ? ILE A 369 THR A 372 
AA3 6 THR A 564 ? LEU A 568 ? THR A 564 LEU A 568 
AA3 7 LEU A 613 ? ALA A 615 ? LEU A 613 ALA A 615 
AA3 8 VAL A 591 ? ILE A 592 ? VAL A 591 ILE A 592 
AA4 1 GLU A 386 ? THR A 389 ? GLU A 386 THR A 389 
AA4 2 LEU A 535 ? LEU A 544 ? LEU A 535 LEU A 544 
AA4 3 LEU A 510 ? PRO A 521 ? LEU A 510 PRO A 521 
AA4 4 HIS A 462 ? ALA A 470 ? HIS A 462 ALA A 470 
AA4 5 ARG A 451 ? ALA A 457 ? ARG A 451 ALA A 457 
AA4 6 GLN A 438 ? ILE A 443 ? GLN A 438 ILE A 443 
AA5 1 GLU A 386 ? THR A 389 ? GLU A 386 THR A 389 
AA5 2 LEU A 535 ? LEU A 544 ? LEU A 535 LEU A 544 
AA5 3 CYS A 478 ? HIS A 483 ? CYS A 478 HIS A 483 
AA5 4 GLU A 486 ? PRO A 489 ? GLU A 486 PRO A 489 
AA6 1 LEU B 172 ? PRO B 175 ? LEU B 172 PRO B 175 
AA6 2 THR B 156 ? VAL B 159 ? THR B 156 VAL B 159 
AA6 3 ILE B 184 ? LEU B 187 ? ILE B 184 LEU B 187 
AA6 4 THR B 245 ? VAL B 255 ? THR B 245 VAL B 255 
AA6 5 LEU B 197 ? ALA B 208 ? LEU B 197 ALA B 208 
AA6 6 VAL B 219 ? LYS B 221 ? VAL B 219 LYS B 221 
AA7 1 LEU B 172 ? PRO B 175 ? LEU B 172 PRO B 175 
AA7 2 THR B 156 ? VAL B 159 ? THR B 156 VAL B 159 
AA7 3 ILE B 184 ? LEU B 187 ? ILE B 184 LEU B 187 
AA7 4 THR B 245 ? VAL B 255 ? THR B 245 VAL B 255 
AA7 5 LEU B 197 ? ALA B 208 ? LEU B 197 ALA B 208 
AA7 6 LEU B 239 ? CYS B 240 ? LEU B 239 CYS B 240 
AA8 1 VAL B 353 ? VAL B 355 ? VAL B 353 VAL B 355 
AA8 2 ILE B 671 ? LEU B 673 ? ILE B 671 LEU B 673 
AA8 3 ILE B 654 ? VAL B 658 ? ILE B 654 VAL B 658 
AA8 4 VAL B 636 ? MET B 639 ? VAL B 636 MET B 639 
AA8 5 ILE B 369 ? THR B 372 ? ILE B 369 THR B 372 
AA8 6 THR B 564 ? LEU B 568 ? THR B 564 LEU B 568 
AA8 7 LEU B 613 ? ALA B 615 ? LEU B 613 ALA B 615 
AA8 8 VAL B 591 ? ILE B 592 ? VAL B 591 ILE B 592 
AA9 1 LEU B 385 ? THR B 389 ? LEU B 385 THR B 389 
AA9 2 LEU B 535 ? LEU B 544 ? LEU B 535 LEU B 544 
AA9 3 LEU B 510 ? PRO B 521 ? LEU B 510 PRO B 521 
AA9 4 HIS B 462 ? ALA B 470 ? HIS B 462 ALA B 470 
AA9 5 ARG B 451 ? ALA B 457 ? ARG B 451 ALA B 457 
AA9 6 GLN B 438 ? ILE B 443 ? GLN B 438 ILE B 443 
AB1 1 LEU B 385 ? THR B 389 ? LEU B 385 THR B 389 
AB1 2 LEU B 535 ? LEU B 544 ? LEU B 535 LEU B 544 
AB1 3 CYS B 478 ? HIS B 483 ? CYS B 478 HIS B 483 
AB1 4 GLU B 486 ? PRO B 489 ? GLU B 486 PRO B 489 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 174 ? O ILE A 174 N ALA A 157 ? N ALA A 157 
AA1 2 3 N THR A 158 ? N THR A 158 O LYS A 186 ? O LYS A 186 
AA1 3 4 N LEU A 187 ? N LEU A 187 O ALA A 251 ? O ALA A 251 
AA1 4 5 O MET A 254 ? O MET A 254 N ARG A 198 ? N ARG A 198 
AA1 5 6 N LEU A 205 ? N LEU A 205 O LYS A 221 ? O LYS A 221 
AA2 1 2 O ILE A 174 ? O ILE A 174 N ALA A 157 ? N ALA A 157 
AA2 2 3 N THR A 158 ? N THR A 158 O LYS A 186 ? O LYS A 186 
AA2 3 4 N LEU A 187 ? N LEU A 187 O ALA A 251 ? O ALA A 251 
AA2 4 5 O MET A 254 ? O MET A 254 N ARG A 198 ? N ARG A 198 
AA2 5 6 N LEU A 197 ? N LEU A 197 O CYS A 240 ? O CYS A 240 
AA3 1 2 N ILE A 354 ? N ILE A 354 O ILE A 672 ? O ILE A 672 
AA3 2 3 O LEU A 673 ? O LEU A 673 N SER A 657 ? N SER A 657 
AA3 3 4 O ILE A 656 ? O ILE A 656 N PHE A 638 ? N PHE A 638 
AA3 4 5 O GLY A 637 ? O GLY A 637 N ILE A 369 ? N ILE A 369 
AA3 5 6 N THR A 372 ? N THR A 372 O LEU A 568 ? O LEU A 568 
AA3 6 7 N ILE A 567 ? N ILE A 567 O PHE A 614 ? O PHE A 614 
AA3 7 8 O ALA A 615 ? O ALA A 615 N VAL A 591 ? N VAL A 591 
AA4 1 2 N ASN A 387 ? N ASN A 387 O ALA A 542 ? O ALA A 542 
AA4 2 3 O ILE A 541 ? O ILE A 541 N VAL A 513 ? N VAL A 513 
AA4 3 4 O LEU A 520 ? O LEU A 520 N HIS A 463 ? N HIS A 463 
AA4 4 5 O VAL A 466 ? O VAL A 466 N VAL A 454 ? N VAL A 454 
AA4 5 6 O SER A 453 ? O SER A 453 N ILE A 443 ? N ILE A 443 
AA5 1 2 N ASN A 387 ? N ASN A 387 O ALA A 542 ? O ALA A 542 
AA5 2 3 O LEU A 537 ? O LEU A 537 N GLN A 480 ? N GLN A 480 
AA5 3 4 N VAL A 481 ? N VAL A 481 O VAL A 488 ? O VAL A 488 
AA6 1 2 O ILE B 174 ? O ILE B 174 N ALA B 157 ? N ALA B 157 
AA6 2 3 N THR B 158 ? N THR B 158 O LYS B 186 ? O LYS B 186 
AA6 3 4 N LEU B 187 ? N LEU B 187 O ALA B 251 ? O ALA B 251 
AA6 4 5 O THR B 250 ? O THR B 250 N ARG B 203 ? N ARG B 203 
AA6 5 6 N LEU B 205 ? N LEU B 205 O LYS B 221 ? O LYS B 221 
AA7 1 2 O ILE B 174 ? O ILE B 174 N ALA B 157 ? N ALA B 157 
AA7 2 3 N THR B 158 ? N THR B 158 O LYS B 186 ? O LYS B 186 
AA7 3 4 N LEU B 187 ? N LEU B 187 O ALA B 251 ? O ALA B 251 
AA7 4 5 O THR B 250 ? O THR B 250 N ARG B 203 ? N ARG B 203 
AA7 5 6 N LEU B 197 ? N LEU B 197 O CYS B 240 ? O CYS B 240 
AA8 1 2 N ILE B 354 ? N ILE B 354 O ILE B 672 ? O ILE B 672 
AA8 2 3 O LEU B 673 ? O LEU B 673 N SER B 657 ? N SER B 657 
AA8 3 4 O ILE B 656 ? O ILE B 656 N PHE B 638 ? N PHE B 638 
AA8 4 5 O GLY B 637 ? O GLY B 637 N ILE B 369 ? N ILE B 369 
AA8 5 6 N THR B 372 ? N THR B 372 O LEU B 568 ? O LEU B 568 
AA8 6 7 N ILE B 567 ? N ILE B 567 O PHE B 614 ? O PHE B 614 
AA8 7 8 O ALA B 615 ? O ALA B 615 N VAL B 591 ? N VAL B 591 
AA9 1 2 N LEU B 385 ? N LEU B 385 O LEU B 544 ? O LEU B 544 
AA9 2 3 O ILE B 541 ? O ILE B 541 N VAL B 513 ? N VAL B 513 
AA9 3 4 O LEU B 520 ? O LEU B 520 N HIS B 463 ? N HIS B 463 
AA9 4 5 O VAL B 466 ? O VAL B 466 N VAL B 454 ? N VAL B 454 
AA9 5 6 O SER B 453 ? O SER B 453 N ILE B 443 ? N ILE B 443 
AB1 1 2 N LEU B 385 ? N LEU B 385 O LEU B 544 ? O LEU B 544 
AB1 2 3 O LEU B 537 ? O LEU B 537 N GLN B 480 ? N GLN B 480 
AB1 3 4 N VAL B 481 ? N VAL B 481 O VAL B 488 ? O VAL B 488 
# 
_pdbx_entry_details.entry_id                   8UYC 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PHE A 2   ? ? 53.21   -97.66  
2  1 HIS A 19  ? ? 67.60   149.79  
3  1 LEU A 23  ? ? 53.42   83.32   
4  1 PRO A 24  ? ? -64.11  60.60   
5  1 THR A 32  ? ? 57.28   19.28   
6  1 VAL A 34  ? ? 52.22   73.05   
7  1 PHE A 119 ? ? 69.41   -3.29   
8  1 ALA A 120 ? ? -92.92  -60.05  
9  1 ARG A 161 ? ? 53.54   -165.92 
10 1 ASN A 164 ? ? 65.34   176.00  
11 1 ALA A 268 ? ? 67.53   -5.57   
12 1 LEU A 328 ? ? -97.58  33.48   
13 1 THR A 340 ? ? -93.38  -60.41  
14 1 ILE A 440 ? ? -120.60 -58.80  
15 1 ASP A 641 ? ? -140.19 37.66   
16 1 PHE A 828 ? ? 72.39   -7.38   
17 1 PHE B 2   ? ? 53.27   -97.66  
18 1 HIS B 19  ? ? 67.55   149.77  
19 1 LEU B 23  ? ? 53.41   83.34   
20 1 PRO B 24  ? ? -64.17  60.56   
21 1 THR B 32  ? ? 57.32   19.22   
22 1 VAL B 34  ? ? 52.19   73.04   
23 1 PHE B 119 ? ? 69.30   -3.23   
24 1 ALA B 120 ? ? -92.92  -60.07  
25 1 ARG B 161 ? ? 53.57   -165.95 
26 1 ASN B 164 ? ? 65.34   176.02  
27 1 ALA B 268 ? ? 67.49   -5.55   
28 1 LEU B 328 ? ? -97.56  33.37   
29 1 THR B 340 ? ? -93.08  -60.53  
30 1 ILE B 440 ? ? -120.54 -58.72  
31 1 PRO B 444 ? ? -69.96  -176.87 
32 1 ASP B 641 ? ? -140.27 37.65   
33 1 PRO B 745 ? ? -49.75  -19.82  
34 1 PHE B 828 ? ? 72.33   -7.33   
# 
loop_
_em_3d_fitting.id 
_em_3d_fitting.entry_id 
_em_3d_fitting.method 
_em_3d_fitting.target_criteria 
_em_3d_fitting.details 
_em_3d_fitting.overall_b_value 
_em_3d_fitting.ref_space 
_em_3d_fitting.ref_protocol 
1 8UYC ? ? ? ? REAL 'RIGID BODY FIT' 
2 8UYC ? ? ? ? REAL 'FLEXIBLE FIT'   
3 8UYC ? ? ? ? REAL 'FLEXIBLE FIT'   
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 . . . ? ? ? AlphaFold 'in silico model' ? ? 
2 2 . . . ? ? ? AlphaFold 'in silico model' ? ? 
3 3 . . . ? ? ? AlphaFold 'in silico model' ? ? 
# 
_em_3d_reconstruction.entry_id                    8UYC 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.75 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               28666 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '50 mM Tris/HCl, 50 mM K2SO4, 5 mM MgCl2, 0.007% glycol-diosgenin, 2 mM DTT, 5 mM ADP' 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Magnesium transporter MgtA from Escherichia coli in the dimeric form in the presence of 5 mM MgCl2 and 5 mM ADP' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8UYC 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        60241 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            100 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   400 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8UYC 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              88 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   278 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UYC 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A HIS 899 ? A HIS 899 
2  1 Y 1 A HIS 900 ? A HIS 900 
3  1 Y 1 A HIS 901 ? A HIS 901 
4  1 Y 1 A HIS 902 ? A HIS 902 
5  1 Y 1 A HIS 903 ? A HIS 903 
6  1 Y 1 A HIS 904 ? A HIS 904 
7  1 Y 1 B HIS 899 ? B HIS 899 
8  1 Y 1 B HIS 900 ? B HIS 900 
9  1 Y 1 B HIS 901 ? B HIS 901 
10 1 Y 1 B HIS 902 ? B HIS 902 
11 1 Y 1 B HIS 903 ? B HIS 903 
12 1 Y 1 B HIS 904 ? B HIS 904 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
MG  MG   MG N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-13 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UYC 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Magnesium transporter MgtA dimer from E. coli in 5 mM MgCl2 and 5 mM ADP' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.201 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               'Escherichia coli K-12' 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              pETDuet-1 
_em_entity_assembly_recombinant.strain               'Escherichia coli C43 (DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             
;A first dataset was collected with a dose rate of 9 A/px/s (~7.5 on the camera through the sample), exposure time 0.076 s/frame (~1 e-/A2) and total exposure time of 3.795 s per movie (~50 e-/A2), resulting in a total of 1897 movies with 50 frames each. 
A second dataset was collected with a dose rate of 9 A/px/s (~7.5 on the camera through the sample), exposure time 0.076 s/frame (~1 e-/A2) and total exposure time of 3.795 s per movie (~50 e-/A2), resulting in a total of 7082 movies with 50 frames each.
;
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    2 
_em_image_recording.num_real_images                     9626 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  
;302,981 particles were initially selected from dataset 1 (1,897 selected movies from 2,519 total).
1,153,466 particles were initially selected from dataset 2 (7,082 selected movies from 7,107 total).
;
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1456447 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? cryoSPARC      ?           
'PARTICLE SELECTION'            ? 2  1 ? ? ?              ?           
'IMAGE ACQUISITION'             ? 3  ? ? 1 SerialEM       3.8-11      
MASKING                         ? 4  ? ? ? ?              ?           
'CTF CORRECTION'                ? 5  1 ? ? cryoSPARC      ?           
'LAYERLINE INDEXING'            ? 6  ? ? ? ?              ?           
'DIFFRACTION INDEXING'          ? 7  ? ? ? ?              ?           
'MODEL FITTING'                 ? 8  ? 1 ? 'UCSF Chimera' 8.6.10      
OTHER                           ? 9  ? ? ? ?              ?           
'MODEL REFINEMENT'              ? 10 ? 1 ? ?              ?           
'IMAGE ACQUISITION'             ? 11 ? ? ? ?              ?           
'CTF CORRECTION'                ? 12 1 ? ? ?              ?           
'MODEL FITTING'                 ? 13 ? 2 ? Coot           0.9.8.7     
'MODEL REFINEMENT'              ? 14 ? 2 ? Coot           0.9.8.7     
'MODEL FITTING'                 ? 15 ? 3 ? PHENIX         1.20.1-4487 
'MODEL REFINEMENT'              ? 16 ? 3 ? PHENIX         1.20.1-4487 
'INITIAL EULER ASSIGNMENT'      ? 17 1 ? ? cryoSPARC      ?           
'INITIAL EULER ASSIGNMENT'      ? 18 1 ? ? ?              ?           
'FINAL EULER ASSIGNMENT'        ? 19 1 ? ? cryoSPARC      ?           
'FINAL EULER ASSIGNMENT'        ? 20 1 ? ? ?              ?           
CLASSIFICATION                  ? 21 1 ? ? cryoSPARC      ?           
CLASSIFICATION                  ? 22 1 ? ? ?              ?           
RECONSTRUCTION                  ? 23 1 ? ? cryoSPARC      ?           
RECONSTRUCTION                  ? 24 1 ? ? ?              ?           
'VOLUME SELECTION'              ? 25 1 1 1 ?              ?           
'SERIES ALIGNMENT'              ? 26 1 1 1 ?              ?           
'MOLECULAR REPLACEMENT'         ? 27 1 1 1 ?              ?           
'LATTICE DISTORTION CORRECTION' ? 28 1 1 1 ?              ?           
'SYMMETRY DETERMINATION'        ? 29 1 1 1 ?              ?           
'CRYSTALLOGRAPHY MERGING'       ? 30 1 1 1 ?              ?           
# 
_em_specimen.concentration           2.3 
_em_specimen.details                 'E. coli MgtA purified with a C-terminal His-tag' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008998'  1 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008855'  2 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008955'  3 
'National Institutes of Health/National Library of Medicine (NIH/NLM)'                                                    
'United States' LM594244        4 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'                                
'United States' 1FI2GM146628-01 5 
'German Research Foundation (DFG)'                                                                                        Germany 
3542/1-1        6 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8UYC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . MET A 1 1   ? 208.838 150.579 162.216 1.00 111.57 ? 1    MET A N   1 
ATOM   2     C  CA  . MET A 1 1   ? 207.630 151.278 162.639 1.00 111.57 ? 1    MET A CA  1 
ATOM   3     C  C   . MET A 1 1   ? 207.882 152.777 162.774 1.00 111.57 ? 1    MET A C   1 
ATOM   4     O  O   . MET A 1 1   ? 207.629 153.540 161.840 1.00 111.57 ? 1    MET A O   1 
ATOM   5     C  CB  . MET A 1 1   ? 207.116 150.708 163.962 1.00 111.57 ? 1    MET A CB  1 
ATOM   6     N  N   . PHE A 1 2   ? 208.389 153.182 163.941 1.00 104.82 ? 2    PHE A N   1 
ATOM   7     C  CA  . PHE A 1 2   ? 208.667 154.582 164.244 1.00 104.82 ? 2    PHE A CA  1 
ATOM   8     C  C   . PHE A 1 2   ? 207.439 155.451 164.002 1.00 104.82 ? 2    PHE A C   1 
ATOM   9     O  O   . PHE A 1 2   ? 206.557 155.540 164.862 1.00 104.82 ? 2    PHE A O   1 
ATOM   10    C  CB  . PHE A 1 2   ? 209.850 155.088 163.413 1.00 104.82 ? 2    PHE A CB  1 
ATOM   11    N  N   . LYS A 1 3   ? 207.383 156.094 162.834 1.00 101.62 ? 3    LYS A N   1 
ATOM   12    C  CA  . LYS A 1 3   ? 206.242 156.917 162.431 1.00 101.62 ? 3    LYS A CA  1 
ATOM   13    C  C   . LYS A 1 3   ? 205.978 158.039 163.432 1.00 101.62 ? 3    LYS A C   1 
ATOM   14    O  O   . LYS A 1 3   ? 204.853 158.234 163.898 1.00 101.62 ? 3    LYS A O   1 
ATOM   15    C  CB  . LYS A 1 3   ? 204.990 156.060 162.229 1.00 101.62 ? 3    LYS A CB  1 
ATOM   16    N  N   . GLU A 1 4   ? 207.033 158.781 163.775 1.00 96.96  ? 4    GLU A N   1 
ATOM   17    C  CA  . GLU A 1 4   ? 206.861 159.963 164.611 1.00 96.96  ? 4    GLU A CA  1 
ATOM   18    C  C   . GLU A 1 4   ? 206.048 161.041 163.908 1.00 96.96  ? 4    GLU A C   1 
ATOM   19    O  O   . GLU A 1 4   ? 205.260 161.737 164.560 1.00 96.96  ? 4    GLU A O   1 
ATOM   20    C  CB  . GLU A 1 4   ? 208.225 160.521 165.024 1.00 96.96  ? 4    GLU A CB  1 
ATOM   21    N  N   . ILE A 1 5   ? 206.202 161.176 162.585 1.00 93.08  ? 5    ILE A N   1 
ATOM   22    C  CA  . ILE A 1 5   ? 205.433 162.153 161.816 1.00 93.08  ? 5    ILE A CA  1 
ATOM   23    C  C   . ILE A 1 5   ? 203.937 161.905 161.879 1.00 93.08  ? 5    ILE A C   1 
ATOM   24    O  O   . ILE A 1 5   ? 203.161 162.753 161.419 1.00 93.08  ? 5    ILE A O   1 
ATOM   25    C  CB  . ILE A 1 5   ? 205.878 162.167 160.339 1.00 93.08  ? 5    ILE A CB  1 
ATOM   26    N  N   . PHE A 1 6   ? 203.505 160.767 162.431 1.00 86.31  ? 6    PHE A N   1 
ATOM   27    C  CA  . PHE A 1 6   ? 202.084 160.555 162.678 1.00 86.31  ? 6    PHE A CA  1 
ATOM   28    C  C   . PHE A 1 6   ? 201.521 161.619 163.606 1.00 86.31  ? 6    PHE A C   1 
ATOM   29    O  O   . PHE A 1 6   ? 200.323 161.918 163.552 1.00 86.31  ? 6    PHE A O   1 
ATOM   30    C  CB  . PHE A 1 6   ? 201.850 159.162 163.265 1.00 86.31  ? 6    PHE A CB  1 
ATOM   31    N  N   . THR A 1 7   ? 202.367 162.204 164.462 1.00 87.90  ? 7    THR A N   1 
ATOM   32    C  CA  . THR A 1 7   ? 201.922 163.325 165.284 1.00 87.90  ? 7    THR A CA  1 
ATOM   33    C  C   . THR A 1 7   ? 201.403 164.463 164.415 1.00 87.90  ? 7    THR A C   1 
ATOM   34    O  O   . THR A 1 7   ? 200.430 165.137 164.774 1.00 87.90  ? 7    THR A O   1 
ATOM   35    C  CB  . THR A 1 7   ? 203.064 163.809 166.177 1.00 87.90  ? 7    THR A CB  1 
ATOM   36    O  OG1 . THR A 1 7   ? 204.199 164.139 165.366 1.00 87.90  ? 7    THR A OG1 1 
ATOM   37    C  CG2 . THR A 1 7   ? 203.457 162.727 167.171 1.00 87.90  ? 7    THR A CG2 1 
ATOM   38    N  N   . ARG A 1 8   ? 202.046 164.695 163.270 1.00 86.20  ? 8    ARG A N   1 
ATOM   39    C  CA  . ARG A 1 8   ? 201.519 165.643 162.294 1.00 86.20  ? 8    ARG A CA  1 
ATOM   40    C  C   . ARG A 1 8   ? 200.200 165.148 161.710 1.00 86.20  ? 8    ARG A C   1 
ATOM   41    O  O   . ARG A 1 8   ? 199.249 165.922 161.547 1.00 86.20  ? 8    ARG A O   1 
ATOM   42    C  CB  . ARG A 1 8   ? 202.550 165.871 161.189 1.00 86.20  ? 8    ARG A CB  1 
ATOM   43    C  CG  . ARG A 1 8   ? 201.979 166.382 159.876 1.00 86.20  ? 8    ARG A CG  1 
ATOM   44    C  CD  . ARG A 1 8   ? 201.800 167.889 159.892 1.00 86.20  ? 8    ARG A CD  1 
ATOM   45    N  NE  . ARG A 1 8   ? 201.250 168.381 158.634 1.00 86.20  ? 8    ARG A NE  1 
ATOM   46    C  CZ  . ARG A 1 8   ? 200.163 169.132 158.534 1.00 86.20  ? 8    ARG A CZ  1 
ATOM   47    N  NH1 . ARG A 1 8   ? 199.481 169.509 159.604 1.00 86.20  ? 8    ARG A NH1 1 
ATOM   48    N  NH2 . ARG A 1 8   ? 199.750 169.518 157.330 1.00 86.20  ? 8    ARG A NH2 1 
ATOM   49    N  N   . LEU A 1 9   ? 200.125 163.854 161.398 1.00 82.50  ? 9    LEU A N   1 
ATOM   50    C  CA  . LEU A 1 9   ? 198.951 163.274 160.755 1.00 82.50  ? 9    LEU A CA  1 
ATOM   51    C  C   . LEU A 1 9   ? 197.721 163.316 161.654 1.00 82.50  ? 9    LEU A C   1 
ATOM   52    O  O   . LEU A 1 9   ? 196.657 163.782 161.234 1.00 82.50  ? 9    LEU A O   1 
ATOM   53    C  CB  . LEU A 1 9   ? 199.240 161.831 160.333 1.00 82.50  ? 9    LEU A CB  1 
ATOM   54    C  CG  . LEU A 1 9   ? 200.273 161.644 159.222 1.00 82.50  ? 9    LEU A CG  1 
ATOM   55    C  CD1 . LEU A 1 9   ? 200.720 160.194 159.135 1.00 82.50  ? 9    LEU A CD1 1 
ATOM   56    C  CD2 . LEU A 1 9   ? 199.697 162.106 157.894 1.00 82.50  ? 9    LEU A CD2 1 
ATOM   57    N  N   . ILE A 1 10  ? 197.851 162.829 162.886 1.00 72.81  ? 10   ILE A N   1 
ATOM   58    C  CA  . ILE A 1 10  ? 196.719 162.754 163.803 1.00 72.81  ? 10   ILE A CA  1 
ATOM   59    C  C   . ILE A 1 10  ? 196.317 164.150 164.257 1.00 72.81  ? 10   ILE A C   1 
ATOM   60    O  O   . ILE A 1 10  ? 197.138 164.902 164.793 1.00 72.81  ? 10   ILE A O   1 
ATOM   61    C  CB  . ILE A 1 10  ? 197.042 161.866 165.018 1.00 72.81  ? 10   ILE A CB  1 
ATOM   62    C  CG1 . ILE A 1 10  ? 197.693 160.559 164.570 1.00 72.81  ? 10   ILE A CG1 1 
ATOM   63    C  CG2 . ILE A 1 10  ? 195.780 161.582 165.813 1.00 72.81  ? 10   ILE A CG2 1 
ATOM   64    C  CD1 . ILE A 1 10  ? 197.956 159.589 165.699 1.00 72.81  ? 10   ILE A CD1 1 
ATOM   65    N  N   . ARG A 1 11  ? 195.053 164.504 164.050 1.00 63.78  ? 11   ARG A N   1 
ATOM   66    C  CA  . ARG A 1 11  ? 194.515 165.723 164.631 1.00 63.78  ? 11   ARG A CA  1 
ATOM   67    C  C   . ARG A 1 11  ? 193.752 165.398 165.908 1.00 63.78  ? 11   ARG A C   1 
ATOM   68    O  O   . ARG A 1 11  ? 192.863 164.542 165.928 1.00 63.78  ? 11   ARG A O   1 
ATOM   69    C  CB  . ARG A 1 11  ? 193.596 166.445 163.646 1.00 63.78  ? 11   ARG A CB  1 
ATOM   70    C  CG  . ARG A 1 11  ? 193.257 167.865 164.072 1.00 63.78  ? 11   ARG A CG  1 
ATOM   71    C  CD  . ARG A 1 11  ? 192.357 168.568 163.069 1.00 63.78  ? 11   ARG A CD  1 
ATOM   72    N  NE  . ARG A 1 11  ? 190.952 168.226 163.254 1.00 63.78  ? 11   ARG A NE  1 
ATOM   73    C  CZ  . ARG A 1 11  ? 190.154 167.790 162.289 1.00 63.78  ? 11   ARG A CZ  1 
ATOM   74    N  NH1 . ARG A 1 11  ? 190.586 167.645 161.048 1.00 63.78  ? 11   ARG A NH1 1 
ATOM   75    N  NH2 . ARG A 1 11  ? 188.888 167.500 162.575 1.00 63.78  ? 11   ARG A NH2 1 
ATOM   76    N  N   . HIS A 1 12  ? 194.109 166.094 166.982 1.00 62.83  ? 12   HIS A N   1 
ATOM   77    C  CA  . HIS A 1 12  ? 193.529 165.868 168.298 1.00 62.83  ? 12   HIS A CA  1 
ATOM   78    C  C   . HIS A 1 12  ? 192.288 166.732 168.464 1.00 62.83  ? 12   HIS A C   1 
ATOM   79    O  O   . HIS A 1 12  ? 192.254 167.875 167.996 1.00 62.83  ? 12   HIS A O   1 
ATOM   80    C  CB  . HIS A 1 12  ? 194.541 166.173 169.403 1.00 62.83  ? 12   HIS A CB  1 
ATOM   81    C  CG  . HIS A 1 12  ? 195.584 165.113 169.576 1.00 62.83  ? 12   HIS A CG  1 
ATOM   82    N  ND1 . HIS A 1 12  ? 195.269 163.790 169.804 1.00 62.83  ? 12   HIS A ND1 1 
ATOM   83    C  CD2 . HIS A 1 12  ? 196.936 165.178 169.552 1.00 62.83  ? 12   HIS A CD2 1 
ATOM   84    C  CE1 . HIS A 1 12  ? 196.382 163.087 169.915 1.00 62.83  ? 12   HIS A CE1 1 
ATOM   85    N  NE2 . HIS A 1 12  ? 197.408 163.906 169.766 1.00 62.83  ? 12   HIS A NE2 1 
ATOM   86    N  N   . LEU A 1 13  ? 191.276 166.182 169.128 1.00 50.55  ? 13   LEU A N   1 
ATOM   87    C  CA  . LEU A 1 13  ? 190.046 166.905 169.419 1.00 50.55  ? 13   LEU A CA  1 
ATOM   88    C  C   . LEU A 1 13  ? 190.360 168.075 170.342 1.00 50.55  ? 13   LEU A C   1 
ATOM   89    O  O   . LEU A 1 13  ? 191.361 168.035 171.069 1.00 50.55  ? 13   LEU A O   1 
ATOM   90    C  CB  . LEU A 1 13  ? 189.012 165.977 170.061 1.00 50.55  ? 13   LEU A CB  1 
ATOM   91    C  CG  . LEU A 1 13  ? 188.504 164.799 169.229 1.00 50.55  ? 13   LEU A CG  1 
ATOM   92    C  CD1 . LEU A 1 13  ? 189.312 163.544 169.518 1.00 50.55  ? 13   LEU A CD1 1 
ATOM   93    C  CD2 . LEU A 1 13  ? 187.029 164.562 169.502 1.00 50.55  ? 13   LEU A CD2 1 
ATOM   94    N  N   . PRO A 1 14  ? 189.554 169.136 170.331 1.00 49.24  ? 14   PRO A N   1 
ATOM   95    C  CA  . PRO A 1 14  ? 189.803 170.257 171.243 1.00 49.24  ? 14   PRO A CA  1 
ATOM   96    C  C   . PRO A 1 14  ? 189.796 169.796 172.694 1.00 49.24  ? 14   PRO A C   1 
ATOM   97    O  O   . PRO A 1 14  ? 189.019 168.923 173.086 1.00 49.24  ? 14   PRO A O   1 
ATOM   98    C  CB  . PRO A 1 14  ? 188.651 171.226 170.948 1.00 49.24  ? 14   PRO A CB  1 
ATOM   99    C  CG  . PRO A 1 14  ? 187.668 170.455 170.124 1.00 49.24  ? 14   PRO A CG  1 
ATOM   100   C  CD  . PRO A 1 14  ? 188.444 169.409 169.405 1.00 49.24  ? 14   PRO A CD  1 
ATOM   101   N  N   . SER A 1 15  ? 190.676 170.395 173.493 1.00 48.48  ? 15   SER A N   1 
ATOM   102   C  CA  . SER A 1 15  ? 190.919 169.966 174.864 1.00 48.48  ? 15   SER A CA  1 
ATOM   103   C  C   . SER A 1 15  ? 189.792 170.338 175.822 1.00 48.48  ? 15   SER A C   1 
ATOM   104   O  O   . SER A 1 15  ? 189.962 170.187 177.038 1.00 48.48  ? 15   SER A O   1 
ATOM   105   C  CB  . SER A 1 15  ? 192.243 170.547 175.365 1.00 48.48  ? 15   SER A CB  1 
ATOM   106   O  OG  . SER A 1 15  ? 192.472 170.201 176.719 1.00 48.48  ? 15   SER A OG  1 
ATOM   107   N  N   . ARG A 1 16  ? 188.657 170.825 175.322 1.00 48.85  ? 16   ARG A N   1 
ATOM   108   C  CA  . ARG A 1 16  ? 187.524 171.169 176.175 1.00 48.85  ? 16   ARG A CA  1 
ATOM   109   C  C   . ARG A 1 16  ? 186.429 170.108 176.124 1.00 48.85  ? 16   ARG A C   1 
ATOM   110   O  O   . ARG A 1 16  ? 185.760 169.856 177.129 1.00 48.85  ? 16   ARG A O   1 
ATOM   111   C  CB  . ARG A 1 16  ? 186.975 172.550 175.788 1.00 48.85  ? 16   ARG A CB  1 
ATOM   112   C  CG  . ARG A 1 16  ? 186.371 172.629 174.400 1.00 48.85  ? 16   ARG A CG  1 
ATOM   113   C  CD  . ARG A 1 16  ? 185.976 174.052 174.059 1.00 48.85  ? 16   ARG A CD  1 
ATOM   114   N  NE  . ARG A 1 16  ? 185.274 174.130 172.785 1.00 48.85  ? 16   ARG A NE  1 
ATOM   115   C  CZ  . ARG A 1 16  ? 185.872 174.236 171.607 1.00 48.85  ? 16   ARG A CZ  1 
ATOM   116   N  NH1 . ARG A 1 16  ? 187.190 174.271 171.502 1.00 48.85  ? 16   ARG A NH1 1 
ATOM   117   N  NH2 . ARG A 1 16  ? 185.129 174.306 170.506 1.00 48.85  ? 16   ARG A NH2 1 
ATOM   118   N  N   . LEU A 1 17  ? 186.231 169.476 174.963 1.00 45.31  ? 17   LEU A N   1 
ATOM   119   C  CA  . LEU A 1 17  ? 185.284 168.368 174.884 1.00 45.31  ? 17   LEU A CA  1 
ATOM   120   C  C   . LEU A 1 17  ? 185.801 167.151 175.637 1.00 45.31  ? 17   LEU A C   1 
ATOM   121   O  O   . LEU A 1 17  ? 185.052 166.503 176.378 1.00 45.31  ? 17   LEU A O   1 
ATOM   122   C  CB  . LEU A 1 17  ? 185.003 168.010 173.425 1.00 45.31  ? 17   LEU A CB  1 
ATOM   123   C  CG  . LEU A 1 17  ? 184.778 169.167 172.456 1.00 45.31  ? 17   LEU A CG  1 
ATOM   124   C  CD1 . LEU A 1 17  ? 184.701 168.640 171.038 1.00 45.31  ? 17   LEU A CD1 1 
ATOM   125   C  CD2 . LEU A 1 17  ? 183.508 169.915 172.819 1.00 45.31  ? 17   LEU A CD2 1 
ATOM   126   N  N   . VAL A 1 18  ? 187.075 166.823 175.458 1.00 44.69  ? 18   VAL A N   1 
ATOM   127   C  CA  . VAL A 1 18  ? 187.711 165.738 176.187 1.00 44.69  ? 18   VAL A CA  1 
ATOM   128   C  C   . VAL A 1 18  ? 188.651 166.344 177.219 1.00 44.69  ? 18   VAL A C   1 
ATOM   129   O  O   . VAL A 1 18  ? 189.038 167.514 177.134 1.00 44.69  ? 18   VAL A O   1 
ATOM   130   C  CB  . VAL A 1 18  ? 188.464 164.772 175.252 1.00 44.69  ? 18   VAL A CB  1 
ATOM   131   C  CG1 . VAL A 1 18  ? 187.494 164.105 174.293 1.00 44.69  ? 18   VAL A CG1 1 
ATOM   132   C  CG2 . VAL A 1 18  ? 189.552 165.511 174.493 1.00 44.69  ? 18   VAL A CG2 1 
ATOM   133   N  N   . HIS A 1 19  ? 189.004 165.530 178.217 1.00 44.52  ? 19   HIS A N   1 
ATOM   134   C  CA  . HIS A 1 19  ? 189.858 165.928 179.334 1.00 44.52  ? 19   HIS A CA  1 
ATOM   135   C  C   . HIS A 1 19  ? 189.162 166.949 180.228 1.00 44.52  ? 19   HIS A C   1 
ATOM   136   O  O   . HIS A 1 19  ? 188.337 167.742 179.763 1.00 44.52  ? 19   HIS A O   1 
ATOM   137   C  CB  . HIS A 1 19  ? 191.202 166.472 178.838 1.00 44.52  ? 19   HIS A CB  1 
ATOM   138   C  CG  . HIS A 1 19  ? 192.299 166.384 179.853 1.00 44.52  ? 19   HIS A CG  1 
ATOM   139   N  ND1 . HIS A 1 19  ? 192.931 165.199 180.163 1.00 44.52  ? 19   HIS A ND1 1 
ATOM   140   C  CD2 . HIS A 1 19  ? 192.878 167.333 180.625 1.00 44.52  ? 19   HIS A CD2 1 
ATOM   141   C  CE1 . HIS A 1 19  ? 193.851 165.422 181.085 1.00 44.52  ? 19   HIS A CE1 1 
ATOM   142   N  NE2 . HIS A 1 19  ? 193.839 166.709 181.382 1.00 44.52  ? 19   HIS A NE2 1 
ATOM   143   N  N   . ARG A 1 20  ? 189.491 166.936 181.515 1.00 42.31  ? 20   ARG A N   1 
ATOM   144   C  CA  . ARG A 1 20  ? 188.791 167.756 182.489 1.00 42.31  ? 20   ARG A CA  1 
ATOM   145   C  C   . ARG A 1 20  ? 189.324 169.188 182.482 1.00 42.31  ? 20   ARG A C   1 
ATOM   146   O  O   . ARG A 1 20  ? 190.203 169.557 181.698 1.00 42.31  ? 20   ARG A O   1 
ATOM   147   C  CB  . ARG A 1 20  ? 188.913 167.140 183.879 1.00 42.31  ? 20   ARG A CB  1 
ATOM   148   C  CG  . ARG A 1 20  ? 188.215 165.804 184.043 1.00 42.31  ? 20   ARG A CG  1 
ATOM   149   C  CD  . ARG A 1 20  ? 188.448 165.247 185.437 1.00 42.31  ? 20   ARG A CD  1 
ATOM   150   N  NE  . ARG A 1 20  ? 187.634 164.068 185.705 1.00 42.31  ? 20   ARG A NE  1 
ATOM   151   C  CZ  . ARG A 1 20  ? 187.630 163.409 186.855 1.00 42.31  ? 20   ARG A CZ  1 
ATOM   152   N  NH1 . ARG A 1 20  ? 188.390 163.786 187.870 1.00 42.31  ? 20   ARG A NH1 1 
ATOM   153   N  NH2 . ARG A 1 20  ? 186.843 162.346 186.990 1.00 42.31  ? 20   ARG A NH2 1 
ATOM   154   N  N   . ASP A 1 21  ? 188.775 170.003 183.376 1.00 55.31  ? 21   ASP A N   1 
ATOM   155   C  CA  . ASP A 1 21  ? 189.132 171.395 183.588 1.00 55.31  ? 21   ASP A CA  1 
ATOM   156   C  C   . ASP A 1 21  ? 190.230 171.511 184.636 1.00 55.31  ? 21   ASP A C   1 
ATOM   157   O  O   . ASP A 1 21  ? 190.483 170.570 185.393 1.00 55.31  ? 21   ASP A O   1 
ATOM   158   C  CB  . ASP A 1 21  ? 187.899 172.194 184.025 1.00 55.31  ? 21   ASP A CB  1 
ATOM   159   C  CG  . ASP A 1 21  ? 186.840 172.264 182.942 1.00 55.31  ? 21   ASP A CG  1 
ATOM   160   O  OD1 . ASP A 1 21  ? 187.062 171.690 181.855 1.00 55.31  ? 21   ASP A OD1 1 
ATOM   161   O  OD2 . ASP A 1 21  ? 185.788 172.897 183.174 1.00 55.31  ? 21   ASP A OD2 1 
ATOM   162   N  N   . PRO A 1 22  ? 190.923 172.655 184.693 1.00 67.82  ? 22   PRO A N   1 
ATOM   163   C  CA  . PRO A 1 22  ? 192.037 172.786 185.652 1.00 67.82  ? 22   PRO A CA  1 
ATOM   164   C  C   . PRO A 1 22  ? 191.666 172.545 187.110 1.00 67.82  ? 22   PRO A C   1 
ATOM   165   O  O   . PRO A 1 22  ? 192.462 171.942 187.841 1.00 67.82  ? 22   PRO A O   1 
ATOM   166   C  CB  . PRO A 1 22  ? 192.512 174.223 185.410 1.00 67.82  ? 22   PRO A CB  1 
ATOM   167   C  CG  . PRO A 1 22  ? 192.211 174.469 183.979 1.00 67.82  ? 22   PRO A CG  1 
ATOM   168   C  CD  . PRO A 1 22  ? 190.916 173.753 183.709 1.00 67.82  ? 22   PRO A CD  1 
ATOM   169   N  N   . LEU A 1 23  ? 190.474 172.978 187.553 1.00 72.63  ? 23   LEU A N   1 
ATOM   170   C  CA  . LEU A 1 23  ? 190.040 172.811 188.941 1.00 72.63  ? 23   LEU A CA  1 
ATOM   171   C  C   . LEU A 1 23  ? 191.067 173.367 189.922 1.00 72.63  ? 23   LEU A C   1 
ATOM   172   O  O   . LEU A 1 23  ? 191.913 172.616 190.425 1.00 72.63  ? 23   LEU A O   1 
ATOM   173   C  CB  . LEU A 1 23  ? 189.748 171.352 189.291 1.00 72.63  ? 23   LEU A CB  1 
ATOM   174   C  CG  . LEU A 1 23  ? 189.174 171.292 190.715 1.00 72.63  ? 23   LEU A CG  1 
ATOM   175   C  CD1 . LEU A 1 23  ? 187.763 171.864 190.751 1.00 72.63  ? 23   LEU A CD1 1 
ATOM   176   C  CD2 . LEU A 1 23  ? 189.222 169.902 191.325 1.00 72.63  ? 23   LEU A CD2 1 
ATOM   177   N  N   . PRO A 1 24  ? 191.056 174.672 190.192 1.00 88.42  ? 24   PRO A N   1 
ATOM   178   C  CA  . PRO A 1 24  ? 192.161 175.279 190.948 1.00 88.42  ? 24   PRO A CA  1 
ATOM   179   C  C   . PRO A 1 24  ? 192.280 174.759 192.373 1.00 88.42  ? 24   PRO A C   1 
ATOM   180   O  O   . PRO A 1 24  ? 192.166 175.520 193.339 1.00 88.42  ? 24   PRO A O   1 
ATOM   181   C  CB  . PRO A 1 24  ? 191.809 176.774 190.947 1.00 88.42  ? 24   PRO A CB  1 
ATOM   182   C  CG  . PRO A 1 24  ? 190.723 176.940 189.920 1.00 88.42  ? 24   PRO A CG  1 
ATOM   183   C  CD  . PRO A 1 24  ? 189.997 175.642 189.875 1.00 88.42  ? 24   PRO A CD  1 
ATOM   184   N  N   . GLY A 1 25  ? 192.504 173.451 192.504 1.00 93.64  ? 25   GLY A N   1 
ATOM   185   C  CA  . GLY A 1 25  ? 192.894 172.841 193.767 1.00 93.64  ? 25   GLY A CA  1 
ATOM   186   C  C   . GLY A 1 25  ? 193.775 171.629 193.492 1.00 93.64  ? 25   GLY A C   1 
ATOM   187   O  O   . GLY A 1 25  ? 193.271 170.507 193.374 1.00 93.64  ? 25   GLY A O   1 
ATOM   188   N  N   . ALA A 1 26  ? 195.091 171.845 193.427 1.00 110.03 ? 26   ALA A N   1 
ATOM   189   C  CA  . ALA A 1 26  ? 196.045 170.809 193.046 1.00 110.03 ? 26   ALA A CA  1 
ATOM   190   C  C   . ALA A 1 26  ? 197.466 171.355 193.081 1.00 110.03 ? 26   ALA A C   1 
ATOM   191   O  O   . ALA A 1 26  ? 197.661 172.573 193.151 1.00 110.03 ? 26   ALA A O   1 
ATOM   192   C  CB  . ALA A 1 26  ? 195.738 170.267 191.647 1.00 110.03 ? 26   ALA A CB  1 
ATOM   193   N  N   . GLN A 1 27  ? 198.458 170.462 193.027 1.00 125.30 ? 27   GLN A N   1 
ATOM   194   C  CA  . GLN A 1 27  ? 199.858 170.854 192.884 1.00 125.30 ? 27   GLN A CA  1 
ATOM   195   C  C   . GLN A 1 27  ? 200.283 171.858 193.949 1.00 125.30 ? 27   GLN A C   1 
ATOM   196   O  O   . GLN A 1 27  ? 200.630 172.999 193.631 1.00 125.30 ? 27   GLN A O   1 
ATOM   197   C  CB  . GLN A 1 27  ? 200.112 171.424 191.488 1.00 125.30 ? 27   GLN A CB  1 
ATOM   198   N  N   . GLN A 1 28  ? 200.246 171.445 195.217 1.00 130.79 ? 28   GLN A N   1 
ATOM   199   C  CA  . GLN A 1 28  ? 200.599 172.325 196.326 1.00 130.79 ? 28   GLN A CA  1 
ATOM   200   C  C   . GLN A 1 28  ? 202.062 172.754 196.308 1.00 130.79 ? 28   GLN A C   1 
ATOM   201   O  O   . GLN A 1 28  ? 202.451 173.581 197.140 1.00 130.79 ? 28   GLN A O   1 
ATOM   202   C  CB  . GLN A 1 28  ? 200.276 171.642 197.655 1.00 130.79 ? 28   GLN A CB  1 
ATOM   203   N  N   . THR A 1 29  ? 202.876 172.215 195.401 1.00 136.66 ? 29   THR A N   1 
ATOM   204   C  CA  . THR A 1 29  ? 204.250 172.674 195.263 1.00 136.66 ? 29   THR A CA  1 
ATOM   205   C  C   . THR A 1 29  ? 204.276 174.102 194.731 1.00 136.66 ? 29   THR A C   1 
ATOM   206   O  O   . THR A 1 29  ? 203.271 174.625 194.242 1.00 136.66 ? 29   THR A O   1 
ATOM   207   C  CB  . THR A 1 29  ? 205.034 171.751 194.329 1.00 136.66 ? 29   THR A CB  1 
ATOM   208   N  N   . VAL A 1 30  ? 205.443 174.734 194.825 1.00 137.94 ? 30   VAL A N   1 
ATOM   209   C  CA  . VAL A 1 30  ? 205.588 176.133 194.440 1.00 137.94 ? 30   VAL A CA  1 
ATOM   210   C  C   . VAL A 1 30  ? 205.833 176.237 192.941 1.00 137.94 ? 30   VAL A C   1 
ATOM   211   O  O   . VAL A 1 30  ? 206.981 176.194 192.483 1.00 137.94 ? 30   VAL A O   1 
ATOM   212   C  CB  . VAL A 1 30  ? 206.723 176.812 195.228 1.00 137.94 ? 30   VAL A CB  1 
ATOM   213   N  N   . ASN A 1 31  ? 204.758 176.370 192.166 1.00 139.47 ? 31   ASN A N   1 
ATOM   214   C  CA  . ASN A 1 31  ? 204.900 176.601 190.736 1.00 139.47 ? 31   ASN A CA  1 
ATOM   215   C  C   . ASN A 1 31  ? 205.431 178.007 190.489 1.00 139.47 ? 31   ASN A C   1 
ATOM   216   O  O   . ASN A 1 31  ? 204.863 178.991 190.975 1.00 139.47 ? 31   ASN A O   1 
ATOM   217   C  CB  . ASN A 1 31  ? 203.557 176.405 190.032 1.00 139.47 ? 31   ASN A CB  1 
ATOM   218   N  N   . THR A 1 32  ? 206.530 178.094 189.737 1.00 136.45 ? 32   THR A N   1 
ATOM   219   C  CA  . THR A 1 32  ? 207.259 179.344 189.503 1.00 136.45 ? 32   THR A CA  1 
ATOM   220   C  C   . THR A 1 32  ? 207.713 179.994 190.809 1.00 136.45 ? 32   THR A C   1 
ATOM   221   O  O   . THR A 1 32  ? 208.031 181.188 190.832 1.00 136.45 ? 32   THR A O   1 
ATOM   222   C  CB  . THR A 1 32  ? 206.434 180.337 188.677 1.00 136.45 ? 32   THR A CB  1 
ATOM   223   N  N   . VAL A 1 33  ? 207.760 179.205 191.884 1.00 136.01 ? 33   VAL A N   1 
ATOM   224   C  CA  . VAL A 1 33  ? 208.176 179.633 193.217 1.00 136.01 ? 33   VAL A CA  1 
ATOM   225   C  C   . VAL A 1 33  ? 207.581 180.985 193.589 1.00 136.01 ? 33   VAL A C   1 
ATOM   226   O  O   . VAL A 1 33  ? 208.309 181.895 194.003 1.00 136.01 ? 33   VAL A O   1 
ATOM   227   C  CB  . VAL A 1 33  ? 209.713 179.676 193.317 1.00 136.01 ? 33   VAL A CB  1 
ATOM   228   N  N   . VAL A 1 34  ? 206.261 181.114 193.466 1.00 134.11 ? 34   VAL A N   1 
ATOM   229   C  CA  . VAL A 1 34  ? 205.545 182.349 193.790 1.00 134.11 ? 34   VAL A CA  1 
ATOM   230   C  C   . VAL A 1 34  ? 206.197 183.514 193.054 1.00 134.11 ? 34   VAL A C   1 
ATOM   231   O  O   . VAL A 1 34  ? 206.884 184.331 193.684 1.00 134.11 ? 34   VAL A O   1 
ATOM   232   C  CB  . VAL A 1 34  ? 205.512 182.599 195.306 1.00 134.11 ? 34   VAL A CB  1 
ATOM   233   N  N   . PRO A 1 35  ? 206.015 183.621 191.739 1.00 130.61 ? 35   PRO A N   1 
ATOM   234   C  CA  . PRO A 1 35  ? 206.828 184.545 190.928 1.00 130.61 ? 35   PRO A CA  1 
ATOM   235   C  C   . PRO A 1 35  ? 206.782 185.961 191.471 1.00 130.61 ? 35   PRO A C   1 
ATOM   236   O  O   . PRO A 1 35  ? 205.721 186.439 191.903 1.00 130.61 ? 35   PRO A O   1 
ATOM   237   C  CB  . PRO A 1 35  ? 206.180 184.459 189.536 1.00 130.61 ? 35   PRO A CB  1 
ATOM   238   C  CG  . PRO A 1 35  ? 204.816 183.880 189.775 1.00 130.61 ? 35   PRO A CG  1 
ATOM   239   C  CD  . PRO A 1 35  ? 204.975 182.957 190.939 1.00 130.61 ? 35   PRO A CD  1 
ATOM   240   N  N   . PRO A 1 36  ? 207.925 186.655 191.478 1.00 125.43 ? 36   PRO A N   1 
ATOM   241   C  CA  . PRO A 1 36  ? 208.007 187.951 192.177 1.00 125.43 ? 36   PRO A CA  1 
ATOM   242   C  C   . PRO A 1 36  ? 207.010 188.990 191.698 1.00 125.43 ? 36   PRO A C   1 
ATOM   243   O  O   . PRO A 1 36  ? 206.507 189.770 192.514 1.00 125.43 ? 36   PRO A O   1 
ATOM   244   C  CB  . PRO A 1 36  ? 209.451 188.393 191.905 1.00 125.43 ? 36   PRO A CB  1 
ATOM   245   C  CG  . PRO A 1 36  ? 210.197 187.125 191.664 1.00 125.43 ? 36   PRO A CG  1 
ATOM   246   C  CD  . PRO A 1 36  ? 209.232 186.214 190.964 1.00 125.43 ? 36   PRO A CD  1 
ATOM   247   N  N   . SER A 1 37  ? 206.712 189.031 190.398 1.00 121.70 ? 37   SER A N   1 
ATOM   248   C  CA  . SER A 1 37  ? 205.771 190.022 189.887 1.00 121.70 ? 37   SER A CA  1 
ATOM   249   C  C   . SER A 1 37  ? 204.386 189.821 190.491 1.00 121.70 ? 37   SER A C   1 
ATOM   250   O  O   . SER A 1 37  ? 203.780 190.760 191.021 1.00 121.70 ? 37   SER A O   1 
ATOM   251   C  CB  . SER A 1 37  ? 205.713 189.949 188.360 1.00 121.70 ? 37   SER A CB  1 
ATOM   252   O  OG  . SER A 1 37  ? 205.316 188.660 187.926 1.00 121.70 ? 37   SER A OG  1 
ATOM   253   N  N   . LEU A 1 38  ? 203.876 188.589 190.428 1.00 120.00 ? 38   LEU A N   1 
ATOM   254   C  CA  . LEU A 1 38  ? 202.546 188.302 190.957 1.00 120.00 ? 38   LEU A CA  1 
ATOM   255   C  C   . LEU A 1 38  ? 202.489 188.527 192.463 1.00 120.00 ? 38   LEU A C   1 
ATOM   256   O  O   . LEU A 1 38  ? 201.534 189.119 192.979 1.00 120.00 ? 38   LEU A O   1 
ATOM   257   C  CB  . LEU A 1 38  ? 202.147 186.867 190.611 1.00 120.00 ? 38   LEU A CB  1 
ATOM   258   C  CG  . LEU A 1 38  ? 200.686 186.488 190.857 1.00 120.00 ? 38   LEU A CG  1 
ATOM   259   C  CD1 . LEU A 1 38  ? 199.759 187.350 190.015 1.00 120.00 ? 38   LEU A CD1 1 
ATOM   260   C  CD2 . LEU A 1 38  ? 200.462 185.012 190.570 1.00 120.00 ? 38   LEU A CD2 1 
ATOM   261   N  N   . SER A 1 39  ? 203.507 188.053 193.185 1.00 121.74 ? 39   SER A N   1 
ATOM   262   C  CA  . SER A 1 39  ? 203.520 188.201 194.637 1.00 121.74 ? 39   SER A CA  1 
ATOM   263   C  C   . SER A 1 39  ? 203.562 189.670 195.037 1.00 121.74 ? 39   SER A C   1 
ATOM   264   O  O   . SER A 1 39  ? 202.828 190.104 195.933 1.00 121.74 ? 39   SER A O   1 
ATOM   265   C  CB  . SER A 1 39  ? 204.710 187.444 195.229 1.00 121.74 ? 39   SER A CB  1 
ATOM   266   O  OG  . SER A 1 39  ? 204.755 187.585 196.638 1.00 121.74 ? 39   SER A OG  1 
ATOM   267   N  N   . ALA A 1 40  ? 204.413 190.455 194.373 1.00 120.02 ? 40   ALA A N   1 
ATOM   268   C  CA  . ALA A 1 40  ? 204.508 191.877 194.679 1.00 120.02 ? 40   ALA A CA  1 
ATOM   269   C  C   . ALA A 1 40  ? 203.207 192.597 194.351 1.00 120.02 ? 40   ALA A C   1 
ATOM   270   O  O   . ALA A 1 40  ? 202.755 193.460 195.114 1.00 120.02 ? 40   ALA A O   1 
ATOM   271   C  CB  . ALA A 1 40  ? 205.678 192.500 193.918 1.00 120.02 ? 40   ALA A CB  1 
ATOM   272   N  N   . HIS A 1 41  ? 202.586 192.254 193.219 1.00 115.57 ? 41   HIS A N   1 
ATOM   273   C  CA  . HIS A 1 41  ? 201.325 192.886 192.849 1.00 115.57 ? 41   HIS A CA  1 
ATOM   274   C  C   . HIS A 1 41  ? 200.238 192.579 193.870 1.00 115.57 ? 41   HIS A C   1 
ATOM   275   O  O   . HIS A 1 41  ? 199.491 193.471 194.286 1.00 115.57 ? 41   HIS A O   1 
ATOM   276   C  CB  . HIS A 1 41  ? 200.898 192.430 191.453 1.00 115.57 ? 41   HIS A CB  1 
ATOM   277   C  CG  . HIS A 1 41  ? 199.589 193.001 191.006 1.00 115.57 ? 41   HIS A CG  1 
ATOM   278   N  ND1 . HIS A 1 41  ? 198.500 192.214 190.697 1.00 115.57 ? 41   HIS A ND1 1 
ATOM   279   C  CD2 . HIS A 1 41  ? 199.193 194.282 190.817 1.00 115.57 ? 41   HIS A CD2 1 
ATOM   280   C  CE1 . HIS A 1 41  ? 197.491 192.986 190.336 1.00 115.57 ? 41   HIS A CE1 1 
ATOM   281   N  NE2 . HIS A 1 41  ? 197.885 194.245 190.401 1.00 115.57 ? 41   HIS A NE2 1 
ATOM   282   N  N   . CYS A 1 42  ? 200.144 191.318 194.296 1.00 116.95 ? 42   CYS A N   1 
ATOM   283   C  CA  . CYS A 1 42  ? 199.147 190.942 195.294 1.00 116.95 ? 42   CYS A CA  1 
ATOM   284   C  C   . CYS A 1 42  ? 199.405 191.648 196.621 1.00 116.95 ? 42   CYS A C   1 
ATOM   285   O  O   . CYS A 1 42  ? 198.475 192.138 197.272 1.00 116.95 ? 42   CYS A O   1 
ATOM   286   C  CB  . CYS A 1 42  ? 199.135 189.424 195.479 1.00 116.95 ? 42   CYS A CB  1 
ATOM   287   S  SG  . CYS A 1 42  ? 198.633 188.495 194.012 1.00 116.95 ? 42   CYS A SG  1 
ATOM   288   N  N   . LEU A 1 43  ? 200.672 191.711 197.038 1.00 114.38 ? 43   LEU A N   1 
ATOM   289   C  CA  . LEU A 1 43  ? 201.004 192.354 198.305 1.00 114.38 ? 43   LEU A CA  1 
ATOM   290   C  C   . LEU A 1 43  ? 200.670 193.840 198.272 1.00 114.38 ? 43   LEU A C   1 
ATOM   291   O  O   . LEU A 1 43  ? 200.150 194.396 199.247 1.00 114.38 ? 43   LEU A O   1 
ATOM   292   C  CB  . LEU A 1 43  ? 202.482 192.137 198.625 1.00 114.38 ? 43   LEU A CB  1 
ATOM   293   C  CG  . LEU A 1 43  ? 202.816 190.733 199.130 1.00 114.38 ? 43   LEU A CG  1 
ATOM   294   C  CD1 . LEU A 1 43  ? 204.316 190.558 199.314 1.00 114.38 ? 43   LEU A CD1 1 
ATOM   295   C  CD2 . LEU A 1 43  ? 202.069 190.447 200.419 1.00 114.38 ? 43   LEU A CD2 1 
ATOM   296   N  N   . LYS A 1 44  ? 200.964 194.502 197.152 1.00 113.14 ? 44   LYS A N   1 
ATOM   297   C  CA  . LYS A 1 44  ? 200.650 195.921 197.024 1.00 113.14 ? 44   LYS A CA  1 
ATOM   298   C  C   . LYS A 1 44  ? 199.144 196.146 196.960 1.00 113.14 ? 44   LYS A C   1 
ATOM   299   O  O   . LYS A 1 44  ? 198.626 197.130 197.502 1.00 113.14 ? 44   LYS A O   1 
ATOM   300   C  CB  . LYS A 1 44  ? 201.351 196.493 195.789 1.00 113.14 ? 44   LYS A CB  1 
ATOM   301   C  CG  . LYS A 1 44  ? 200.593 197.591 195.064 1.00 113.14 ? 44   LYS A CG  1 
ATOM   302   C  CD  . LYS A 1 44  ? 201.321 197.995 193.791 1.00 113.14 ? 44   LYS A CD  1 
ATOM   303   C  CE  . LYS A 1 44  ? 200.455 198.874 192.905 1.00 113.14 ? 44   LYS A CE  1 
ATOM   304   N  NZ  . LYS A 1 44  ? 199.260 198.144 192.403 1.00 113.14 ? 44   LYS A NZ  1 
ATOM   305   N  N   . MET A 1 45  ? 198.419 195.233 196.308 1.00 108.34 ? 45   MET A N   1 
ATOM   306   C  CA  . MET A 1 45  ? 196.977 195.394 196.165 1.00 108.34 ? 45   MET A CA  1 
ATOM   307   C  C   . MET A 1 45  ? 196.237 195.092 197.462 1.00 108.34 ? 45   MET A C   1 
ATOM   308   O  O   . MET A 1 45  ? 195.116 195.574 197.660 1.00 108.34 ? 45   MET A O   1 
ATOM   309   C  CB  . MET A 1 45  ? 196.465 194.493 195.041 1.00 108.34 ? 45   MET A CB  1 
ATOM   310   C  CG  . MET A 1 45  ? 196.677 195.057 193.647 1.00 108.34 ? 45   MET A CG  1 
ATOM   311   S  SD  . MET A 1 45  ? 195.583 196.443 193.294 1.00 108.34 ? 45   MET A SD  1 
ATOM   312   C  CE  . MET A 1 45  ? 194.077 195.881 194.083 1.00 108.34 ? 45   MET A CE  1 
ATOM   313   N  N   . ALA A 1 46  ? 196.836 194.292 198.346 1.00 106.25 ? 46   ALA A N   1 
ATOM   314   C  CA  . ALA A 1 46  ? 196.170 193.936 199.595 1.00 106.25 ? 46   ALA A CA  1 
ATOM   315   C  C   . ALA A 1 46  ? 195.922 195.166 200.461 1.00 106.25 ? 46   ALA A C   1 
ATOM   316   O  O   . ALA A 1 46  ? 194.777 195.485 200.801 1.00 106.25 ? 46   ALA A O   1 
ATOM   317   C  CB  . ALA A 1 46  ? 197.002 192.900 200.353 1.00 106.25 ? 46   ALA A CB  1 
ATOM   318   N  N   . VAL A 1 47  ? 196.994 195.880 200.822 1.00 110.72 ? 47   VAL A N   1 
ATOM   319   C  CA  . VAL A 1 47  ? 196.874 197.047 201.695 1.00 110.72 ? 47   VAL A CA  1 
ATOM   320   C  C   . VAL A 1 47  ? 196.565 198.326 200.936 1.00 110.72 ? 47   VAL A C   1 
ATOM   321   O  O   . VAL A 1 47  ? 196.696 199.417 201.507 1.00 110.72 ? 47   VAL A O   1 
ATOM   322   C  CB  . VAL A 1 47  ? 198.157 197.241 202.527 1.00 110.72 ? 47   VAL A CB  1 
ATOM   323   C  CG1 . VAL A 1 47  ? 198.368 196.055 203.452 1.00 110.72 ? 47   VAL A CG1 1 
ATOM   324   C  CG2 . VAL A 1 47  ? 199.358 197.426 201.614 1.00 110.72 ? 47   VAL A CG2 1 
ATOM   325   N  N   . MET A 1 48  ? 196.174 198.228 199.669 1.00 111.92 ? 48   MET A N   1 
ATOM   326   C  CA  . MET A 1 48  ? 195.844 199.390 198.860 1.00 111.92 ? 48   MET A CA  1 
ATOM   327   C  C   . MET A 1 48  ? 194.716 200.191 199.510 1.00 111.92 ? 48   MET A C   1 
ATOM   328   O  O   . MET A 1 48  ? 193.691 199.606 199.892 1.00 111.92 ? 48   MET A O   1 
ATOM   329   C  CB  . MET A 1 48  ? 195.429 198.954 197.457 1.00 111.92 ? 48   MET A CB  1 
ATOM   330   C  CG  . MET A 1 48  ? 195.244 200.100 196.477 1.00 111.92 ? 48   MET A CG  1 
ATOM   331   S  SD  . MET A 1 48  ? 196.805 200.794 195.905 1.00 111.92 ? 48   MET A SD  1 
ATOM   332   C  CE  . MET A 1 48  ? 197.422 199.442 194.907 1.00 111.92 ? 48   MET A CE  1 
ATOM   333   N  N   . PRO A 1 49  ? 194.870 201.504 199.670 1.00 111.76 ? 49   PRO A N   1 
ATOM   334   C  CA  . PRO A 1 49  ? 193.769 202.321 200.192 1.00 111.76 ? 49   PRO A CA  1 
ATOM   335   C  C   . PRO A 1 49  ? 192.538 202.228 199.301 1.00 111.76 ? 49   PRO A C   1 
ATOM   336   O  O   . PRO A 1 49  ? 192.637 202.118 198.077 1.00 111.76 ? 49   PRO A O   1 
ATOM   337   C  CB  . PRO A 1 49  ? 194.355 203.736 200.203 1.00 111.76 ? 49   PRO A CB  1 
ATOM   338   C  CG  . PRO A 1 49  ? 195.823 203.528 200.336 1.00 111.76 ? 49   PRO A CG  1 
ATOM   339   C  CD  . PRO A 1 49  ? 196.134 202.257 199.593 1.00 111.76 ? 49   PRO A CD  1 
ATOM   340   N  N   . GLU A 1 50  ? 191.364 202.272 199.935 1.00 114.67 ? 50   GLU A N   1 
ATOM   341   C  CA  . GLU A 1 50  ? 190.113 202.075 199.211 1.00 114.67 ? 50   GLU A CA  1 
ATOM   342   C  C   . GLU A 1 50  ? 189.837 203.213 198.235 1.00 114.67 ? 50   GLU A C   1 
ATOM   343   O  O   . GLU A 1 50  ? 189.173 203.014 197.211 1.00 114.67 ? 50   GLU A O   1 
ATOM   344   C  CB  . GLU A 1 50  ? 188.960 201.927 200.205 1.00 114.67 ? 50   GLU A CB  1 
ATOM   345   C  CG  . GLU A 1 50  ? 187.690 201.338 199.615 1.00 114.67 ? 50   GLU A CG  1 
ATOM   346   C  CD  . GLU A 1 50  ? 186.665 202.398 199.261 1.00 114.67 ? 50   GLU A CD  1 
ATOM   347   O  OE1 . GLU A 1 50  ? 186.965 203.598 199.432 1.00 114.67 ? 50   GLU A OE1 1 
ATOM   348   O  OE2 . GLU A 1 50  ? 185.557 202.030 198.818 1.00 114.67 ? 50   GLU A OE2 1 
ATOM   349   N  N   . GLU A 1 51  ? 190.331 204.416 198.538 1.00 116.86 ? 51   GLU A N   1 
ATOM   350   C  CA  . GLU A 1 51  ? 190.028 205.573 197.699 1.00 116.86 ? 51   GLU A CA  1 
ATOM   351   C  C   . GLU A 1 51  ? 190.623 205.421 196.304 1.00 116.86 ? 51   GLU A C   1 
ATOM   352   O  O   . GLU A 1 51  ? 189.920 205.568 195.297 1.00 116.86 ? 51   GLU A O   1 
ATOM   353   C  CB  . GLU A 1 51  ? 190.538 206.852 198.363 1.00 116.86 ? 51   GLU A CB  1 
ATOM   354   C  CG  . GLU A 1 51  ? 190.469 208.076 197.465 1.00 116.86 ? 51   GLU A CG  1 
ATOM   355   C  CD  . GLU A 1 51  ? 191.259 209.248 198.011 1.00 116.86 ? 51   GLU A CD  1 
ATOM   356   O  OE1 . GLU A 1 51  ? 191.858 209.108 199.098 1.00 116.86 ? 51   GLU A OE1 1 
ATOM   357   O  OE2 . GLU A 1 51  ? 191.282 210.309 197.352 1.00 116.86 ? 51   GLU A OE2 1 
ATOM   358   N  N   . GLU A 1 52  ? 191.921 205.123 196.221 1.00 114.96 ? 52   GLU A N   1 
ATOM   359   C  CA  . GLU A 1 52  ? 192.568 204.997 194.921 1.00 114.96 ? 52   GLU A CA  1 
ATOM   360   C  C   . GLU A 1 52  ? 192.276 203.665 194.245 1.00 114.96 ? 52   GLU A C   1 
ATOM   361   O  O   . GLU A 1 52  ? 192.642 203.489 193.077 1.00 114.96 ? 52   GLU A O   1 
ATOM   362   C  CB  . GLU A 1 52  ? 194.079 205.196 195.059 1.00 114.96 ? 52   GLU A CB  1 
ATOM   363   C  CG  . GLU A 1 52  ? 194.744 204.336 196.119 1.00 114.96 ? 52   GLU A CG  1 
ATOM   364   C  CD  . GLU A 1 52  ? 196.255 204.466 196.099 1.00 114.96 ? 52   GLU A CD  1 
ATOM   365   O  OE1 . GLU A 1 52  ? 196.776 205.218 195.249 1.00 114.96 ? 52   GLU A OE1 1 
ATOM   366   O  OE2 . GLU A 1 52  ? 196.923 203.822 196.934 1.00 114.96 ? 52   GLU A OE2 1 
ATOM   367   N  N   . LEU A 1 53  ? 191.633 202.728 194.947 1.00 110.07 ? 53   LEU A N   1 
ATOM   368   C  CA  . LEU A 1 53  ? 191.218 201.482 194.312 1.00 110.07 ? 53   LEU A CA  1 
ATOM   369   C  C   . LEU A 1 53  ? 190.228 201.735 193.185 1.00 110.07 ? 53   LEU A C   1 
ATOM   370   O  O   . LEU A 1 53  ? 190.252 201.035 192.167 1.00 110.07 ? 53   LEU A O   1 
ATOM   371   C  CB  . LEU A 1 53  ? 190.608 200.543 195.353 1.00 110.07 ? 53   LEU A CB  1 
ATOM   372   C  CG  . LEU A 1 53  ? 190.242 199.141 194.867 1.00 110.07 ? 53   LEU A CG  1 
ATOM   373   C  CD1 . LEU A 1 53  ? 191.494 198.319 194.639 1.00 110.07 ? 53   LEU A CD1 1 
ATOM   374   C  CD2 . LEU A 1 53  ? 189.322 198.454 195.860 1.00 110.07 ? 53   LEU A CD2 1 
ATOM   375   N  N   . TRP A 1 54  ? 189.351 202.726 193.351 1.00 111.07 ? 54   TRP A N   1 
ATOM   376   C  CA  . TRP A 1 54  ? 188.392 203.065 192.306 1.00 111.07 ? 54   TRP A CA  1 
ATOM   377   C  C   . TRP A 1 54  ? 189.103 203.545 191.047 1.00 111.07 ? 54   TRP A C   1 
ATOM   378   O  O   . TRP A 1 54  ? 188.738 203.169 189.927 1.00 111.07 ? 54   TRP A O   1 
ATOM   379   C  CB  . TRP A 1 54  ? 187.425 204.131 192.823 1.00 111.07 ? 54   TRP A CB  1 
ATOM   380   C  CG  . TRP A 1 54  ? 186.698 203.721 194.065 1.00 111.07 ? 54   TRP A CG  1 
ATOM   381   C  CD1 . TRP A 1 54  ? 186.904 204.193 195.328 1.00 111.07 ? 54   TRP A CD1 1 
ATOM   382   C  CD2 . TRP A 1 54  ? 185.646 202.754 194.165 1.00 111.07 ? 54   TRP A CD2 1 
ATOM   383   N  NE1 . TRP A 1 54  ? 186.047 203.580 196.209 1.00 111.07 ? 54   TRP A NE1 1 
ATOM   384   C  CE2 . TRP A 1 54  ? 185.264 202.692 195.520 1.00 111.07 ? 54   TRP A CE2 1 
ATOM   385   C  CE3 . TRP A 1 54  ? 184.990 201.936 193.242 1.00 111.07 ? 54   TRP A CE3 1 
ATOM   386   C  CZ2 . TRP A 1 54  ? 184.256 201.845 195.972 1.00 111.07 ? 54   TRP A CZ2 1 
ATOM   387   C  CZ3 . TRP A 1 54  ? 183.990 201.096 193.693 1.00 111.07 ? 54   TRP A CZ3 1 
ATOM   388   C  CH2 . TRP A 1 54  ? 183.633 201.056 195.046 1.00 111.07 ? 54   TRP A CH2 1 
ATOM   389   N  N   . LYS A 1 55  ? 190.130 204.382 191.214 1.00 113.59 ? 55   LYS A N   1 
ATOM   390   C  CA  . LYS A 1 55  ? 190.864 204.895 190.063 1.00 113.59 ? 55   LYS A CA  1 
ATOM   391   C  C   . LYS A 1 55  ? 191.755 203.830 189.439 1.00 113.59 ? 55   LYS A C   1 
ATOM   392   O  O   . LYS A 1 55  ? 191.978 203.845 188.223 1.00 113.59 ? 55   LYS A O   1 
ATOM   393   C  CB  . LYS A 1 55  ? 191.699 206.109 190.470 1.00 113.59 ? 55   LYS A CB  1 
ATOM   394   C  CG  . LYS A 1 55  ? 190.881 207.332 190.844 1.00 113.59 ? 55   LYS A CG  1 
ATOM   395   C  CD  . LYS A 1 55  ? 191.776 208.469 191.312 1.00 113.59 ? 55   LYS A CD  1 
ATOM   396   C  CE  . LYS A 1 55  ? 191.014 209.782 191.371 1.00 113.59 ? 55   LYS A CE  1 
ATOM   397   N  NZ  . LYS A 1 55  ? 191.862 210.896 191.878 1.00 113.59 ? 55   LYS A NZ  1 
ATOM   398   N  N   . THR A 1 56  ? 192.278 202.907 190.251 1.00 109.09 ? 56   THR A N   1 
ATOM   399   C  CA  . THR A 1 56  ? 193.204 201.904 189.732 1.00 109.09 ? 56   THR A CA  1 
ATOM   400   C  C   . THR A 1 56  ? 192.541 201.021 188.683 1.00 109.09 ? 56   THR A C   1 
ATOM   401   O  O   . THR A 1 56  ? 193.131 200.742 187.632 1.00 109.09 ? 56   THR A O   1 
ATOM   402   C  CB  . THR A 1 56  ? 193.749 201.052 190.879 1.00 109.09 ? 56   THR A CB  1 
ATOM   403   O  OG1 . THR A 1 56  ? 194.522 201.874 191.762 1.00 109.09 ? 56   THR A OG1 1 
ATOM   404   C  CG2 . THR A 1 56  ? 194.626 199.930 190.345 1.00 109.09 ? 56   THR A CG2 1 
ATOM   405   N  N   . PHE A 1 57  ? 191.312 200.581 188.941 1.00 107.44 ? 57   PHE A N   1 
ATOM   406   C  CA  . PHE A 1 57  ? 190.599 199.689 188.037 1.00 107.44 ? 57   PHE A CA  1 
ATOM   407   C  C   . PHE A 1 57  ? 189.473 200.383 187.283 1.00 107.44 ? 57   PHE A C   1 
ATOM   408   O  O   . PHE A 1 57  ? 188.668 199.703 186.638 1.00 107.44 ? 57   PHE A O   1 
ATOM   409   C  CB  . PHE A 1 57  ? 190.051 198.488 188.809 1.00 107.44 ? 57   PHE A CB  1 
ATOM   410   C  CG  . PHE A 1 57  ? 191.116 197.566 189.321 1.00 107.44 ? 57   PHE A CG  1 
ATOM   411   C  CD1 . PHE A 1 57  ? 191.640 196.574 188.509 1.00 107.44 ? 57   PHE A CD1 1 
ATOM   412   C  CD2 . PHE A 1 57  ? 191.600 197.695 190.610 1.00 107.44 ? 57   PHE A CD2 1 
ATOM   413   C  CE1 . PHE A 1 57  ? 192.623 195.726 188.976 1.00 107.44 ? 57   PHE A CE1 1 
ATOM   414   C  CE2 . PHE A 1 57  ? 192.583 196.850 191.082 1.00 107.44 ? 57   PHE A CE2 1 
ATOM   415   C  CZ  . PHE A 1 57  ? 193.096 195.864 190.264 1.00 107.44 ? 57   PHE A CZ  1 
ATOM   416   N  N   . ASP A 1 58  ? 189.404 201.713 187.345 1.00 111.61 ? 58   ASP A N   1 
ATOM   417   C  CA  . ASP A 1 58  ? 188.381 202.488 186.642 1.00 111.61 ? 58   ASP A CA  1 
ATOM   418   C  C   . ASP A 1 58  ? 186.980 202.008 187.017 1.00 111.61 ? 58   ASP A C   1 
ATOM   419   O  O   . ASP A 1 58  ? 186.149 201.695 186.163 1.00 111.61 ? 58   ASP A O   1 
ATOM   420   C  CB  . ASP A 1 58  ? 188.594 202.429 185.128 1.00 111.61 ? 58   ASP A CB  1 
ATOM   421   C  CG  . ASP A 1 58  ? 189.871 203.118 184.691 1.00 111.61 ? 58   ASP A CG  1 
ATOM   422   O  OD1 . ASP A 1 58  ? 190.305 204.064 185.382 1.00 111.61 ? 58   ASP A OD1 1 
ATOM   423   O  OD2 . ASP A 1 58  ? 190.442 202.712 183.657 1.00 111.61 ? 58   ASP A OD2 1 
ATOM   424   N  N   . THR A 1 59  ? 186.725 201.944 188.320 1.00 109.71 ? 59   THR A N   1 
ATOM   425   C  CA  . THR A 1 59  ? 185.473 201.428 188.849 1.00 109.71 ? 59   THR A CA  1 
ATOM   426   C  C   . THR A 1 59  ? 184.797 202.489 189.706 1.00 109.71 ? 59   THR A C   1 
ATOM   427   O  O   . THR A 1 59  ? 185.465 203.245 190.419 1.00 109.71 ? 59   THR A O   1 
ATOM   428   C  CB  . THR A 1 59  ? 185.707 200.159 189.676 1.00 109.71 ? 59   THR A CB  1 
ATOM   429   O  OG1 . THR A 1 59  ? 186.483 199.229 188.910 1.00 109.71 ? 59   THR A OG1 1 
ATOM   430   C  CG2 . THR A 1 59  ? 184.382 199.510 190.053 1.00 109.71 ? 59   THR A CG2 1 
ATOM   431   N  N   . HIS A 1 60  ? 183.471 202.543 189.627 1.00 109.25 ? 60   HIS A N   1 
ATOM   432   C  CA  . HIS A 1 60  ? 182.659 203.439 190.427 1.00 109.25 ? 60   HIS A CA  1 
ATOM   433   C  C   . HIS A 1 60  ? 181.893 202.655 191.488 1.00 109.25 ? 60   HIS A C   1 
ATOM   434   O  O   . HIS A 1 60  ? 181.632 201.460 191.313 1.00 109.25 ? 60   HIS A O   1 
ATOM   435   C  CB  . HIS A 1 60  ? 181.668 204.213 189.550 1.00 109.25 ? 60   HIS A CB  1 
ATOM   436   C  CG  . HIS A 1 60  ? 182.176 204.493 188.170 1.00 109.25 ? 60   HIS A CG  1 
ATOM   437   N  ND1 . HIS A 1 60  ? 183.346 205.182 187.934 1.00 109.25 ? 60   HIS A ND1 1 
ATOM   438   C  CD2 . HIS A 1 60  ? 181.673 204.177 186.953 1.00 109.25 ? 60   HIS A CD2 1 
ATOM   439   C  CE1 . HIS A 1 60  ? 183.542 205.278 186.631 1.00 109.25 ? 60   HIS A CE1 1 
ATOM   440   N  NE2 . HIS A 1 60  ? 182.541 204.677 186.013 1.00 109.25 ? 60   HIS A NE2 1 
ATOM   441   N  N   . PRO A 1 61  ? 181.539 203.289 192.609 1.00 109.23 ? 61   PRO A N   1 
ATOM   442   C  CA  . PRO A 1 61  ? 180.778 202.568 193.643 1.00 109.23 ? 61   PRO A CA  1 
ATOM   443   C  C   . PRO A 1 61  ? 179.465 201.994 193.144 1.00 109.23 ? 61   PRO A C   1 
ATOM   444   O  O   . PRO A 1 61  ? 179.069 200.906 193.581 1.00 109.23 ? 61   PRO A O   1 
ATOM   445   C  CB  . PRO A 1 61  ? 180.553 203.639 194.718 1.00 109.23 ? 61   PRO A CB  1 
ATOM   446   C  CG  . PRO A 1 61  ? 181.684 204.590 194.540 1.00 109.23 ? 61   PRO A CG  1 
ATOM   447   C  CD  . PRO A 1 61  ? 181.962 204.625 193.063 1.00 109.23 ? 61   PRO A CD  1 
ATOM   448   N  N   . GLU A 1 62  ? 178.776 202.690 192.238 1.00 109.36 ? 62   GLU A N   1 
ATOM   449   C  CA  . GLU A 1 62  ? 177.505 202.192 191.729 1.00 109.36 ? 62   GLU A CA  1 
ATOM   450   C  C   . GLU A 1 62  ? 177.675 200.998 190.798 1.00 109.36 ? 62   GLU A C   1 
ATOM   451   O  O   . GLU A 1 62  ? 176.700 200.282 190.547 1.00 109.36 ? 62   GLU A O   1 
ATOM   452   C  CB  . GLU A 1 62  ? 176.752 203.312 191.009 1.00 109.36 ? 62   GLU A CB  1 
ATOM   453   C  CG  . GLU A 1 62  ? 177.360 203.714 189.678 1.00 109.36 ? 62   GLU A CG  1 
ATOM   454   C  CD  . GLU A 1 62  ? 178.312 204.886 189.802 1.00 109.36 ? 62   GLU A CD  1 
ATOM   455   O  OE1 . GLU A 1 62  ? 178.712 205.212 190.940 1.00 109.36 ? 62   GLU A OE1 1 
ATOM   456   O  OE2 . GLU A 1 62  ? 178.662 205.480 188.761 1.00 109.36 ? 62   GLU A OE2 1 
ATOM   457   N  N   . GLY A 1 63  ? 178.884 200.764 190.283 1.00 108.34 ? 63   GLY A N   1 
ATOM   458   C  CA  . GLY A 1 63  ? 179.148 199.639 189.411 1.00 108.34 ? 63   GLY A CA  1 
ATOM   459   C  C   . GLY A 1 63  ? 179.673 200.089 188.058 1.00 108.34 ? 63   GLY A C   1 
ATOM   460   O  O   . GLY A 1 63  ? 180.246 201.177 187.925 1.00 108.34 ? 63   GLY A O   1 
ATOM   461   N  N   . LEU A 1 64  ? 179.462 199.240 187.054 1.00 106.51 ? 64   LEU A N   1 
ATOM   462   C  CA  . LEU A 1 64  ? 179.937 199.492 185.702 1.00 106.51 ? 64   LEU A CA  1 
ATOM   463   C  C   . LEU A 1 64  ? 178.776 199.397 184.726 1.00 106.51 ? 64   LEU A C   1 
ATOM   464   O  O   . LEU A 1 64  ? 177.908 198.530 184.864 1.00 106.51 ? 64   LEU A O   1 
ATOM   465   C  CB  . LEU A 1 64  ? 181.032 198.494 185.299 1.00 106.51 ? 64   LEU A CB  1 
ATOM   466   C  CG  . LEU A 1 64  ? 182.284 198.414 186.174 1.00 106.51 ? 64   LEU A CG  1 
ATOM   467   C  CD1 . LEU A 1 64  ? 183.338 197.540 185.513 1.00 106.51 ? 64   LEU A CD1 1 
ATOM   468   C  CD2 . LEU A 1 64  ? 182.834 199.801 186.451 1.00 106.51 ? 64   LEU A CD2 1 
ATOM   469   N  N   . ASN A 1 65  ? 178.765 200.286 183.735 1.00 108.67 ? 65   ASN A N   1 
ATOM   470   C  CA  . ASN A 1 65  ? 177.764 200.228 182.684 1.00 108.67 ? 65   ASN A CA  1 
ATOM   471   C  C   . ASN A 1 65  ? 178.306 199.418 181.506 1.00 108.67 ? 65   ASN A C   1 
ATOM   472   O  O   . ASN A 1 65  ? 179.395 198.842 181.567 1.00 108.67 ? 65   ASN A O   1 
ATOM   473   C  CB  . ASN A 1 65  ? 177.336 201.638 182.270 1.00 108.67 ? 65   ASN A CB  1 
ATOM   474   C  CG  . ASN A 1 65  ? 178.509 202.531 181.912 1.00 108.67 ? 65   ASN A CG  1 
ATOM   475   O  OD1 . ASN A 1 65  ? 179.645 202.073 181.807 1.00 108.67 ? 65   ASN A OD1 1 
ATOM   476   N  ND2 . ASN A 1 65  ? 178.234 203.816 181.716 1.00 108.67 ? 65   ASN A ND2 1 
ATOM   477   N  N   . GLN A 1 66  ? 177.532 199.363 180.421 1.00 105.83 ? 66   GLN A N   1 
ATOM   478   C  CA  . GLN A 1 66  ? 177.870 198.507 179.289 1.00 105.83 ? 66   GLN A CA  1 
ATOM   479   C  C   . GLN A 1 66  ? 179.200 198.889 178.651 1.00 105.83 ? 66   GLN A C   1 
ATOM   480   O  O   . GLN A 1 66  ? 180.167 198.122 178.714 1.00 105.83 ? 66   GLN A O   1 
ATOM   481   C  CB  . GLN A 1 66  ? 176.759 198.555 178.238 1.00 105.83 ? 66   GLN A CB  1 
ATOM   482   N  N   . ALA A 1 67  ? 179.278 200.095 178.085 1.00 109.79 ? 67   ALA A N   1 
ATOM   483   C  CA  . ALA A 1 67  ? 180.470 200.477 177.334 1.00 109.79 ? 67   ALA A CA  1 
ATOM   484   C  C   . ALA A 1 67  ? 181.731 200.230 178.150 1.00 109.79 ? 67   ALA A C   1 
ATOM   485   O  O   . ALA A 1 67  ? 182.729 199.718 177.631 1.00 109.79 ? 67   ALA A O   1 
ATOM   486   C  CB  . ALA A 1 67  ? 180.374 201.943 176.908 1.00 109.79 ? 67   ALA A CB  1 
ATOM   487   N  N   . GLU A 1 68  ? 181.674 200.521 179.451 1.00 110.00 ? 68   GLU A N   1 
ATOM   488   C  CA  . GLU A 1 68  ? 182.811 200.255 180.324 1.00 110.00 ? 68   GLU A CA  1 
ATOM   489   C  C   . GLU A 1 68  ? 183.102 198.761 180.434 1.00 110.00 ? 68   GLU A C   1 
ATOM   490   O  O   . GLU A 1 68  ? 184.269 198.359 180.444 1.00 110.00 ? 68   GLU A O   1 
ATOM   491   C  CB  . GLU A 1 68  ? 182.565 200.865 181.703 1.00 110.00 ? 68   GLU A CB  1 
ATOM   492   C  CG  . GLU A 1 68  ? 183.836 201.279 182.427 1.00 110.00 ? 68   GLU A CG  1 
ATOM   493   C  CD  . GLU A 1 68  ? 183.565 202.178 183.618 1.00 110.00 ? 68   GLU A CD  1 
ATOM   494   O  OE1 . GLU A 1 68  ? 182.385 202.335 183.997 1.00 110.00 ? 68   GLU A OE1 1 
ATOM   495   O  OE2 . GLU A 1 68  ? 184.534 202.747 184.160 1.00 110.00 ? 68   GLU A OE2 1 
ATOM   496   N  N   . VAL A 1 69  ? 182.068 197.916 180.524 1.00 106.81 ? 69   VAL A N   1 
ATOM   497   C  CA  . VAL A 1 69  ? 182.339 196.496 180.746 1.00 106.81 ? 69   VAL A CA  1 
ATOM   498   C  C   . VAL A 1 69  ? 182.913 195.851 179.486 1.00 106.81 ? 69   VAL A C   1 
ATOM   499   O  O   . VAL A 1 69  ? 183.851 195.051 179.567 1.00 106.81 ? 69   VAL A O   1 
ATOM   500   C  CB  . VAL A 1 69  ? 181.096 195.746 181.275 1.00 106.81 ? 69   VAL A CB  1 
ATOM   501   C  CG1 . VAL A 1 69  ? 179.990 195.635 180.245 1.00 106.81 ? 69   VAL A CG1 1 
ATOM   502   C  CG2 . VAL A 1 69  ? 181.495 194.368 181.779 1.00 106.81 ? 69   VAL A CG2 1 
ATOM   503   N  N   . GLU A 1 70  ? 182.387 196.191 178.302 1.00 108.06 ? 70   GLU A N   1 
ATOM   504   C  CA  . GLU A 1 70  ? 183.030 195.693 177.084 1.00 108.06 ? 70   GLU A CA  1 
ATOM   505   C  C   . GLU A 1 70  ? 184.424 196.284 176.885 1.00 108.06 ? 70   GLU A C   1 
ATOM   506   O  O   . GLU A 1 70  ? 185.324 195.594 176.392 1.00 108.06 ? 70   GLU A O   1 
ATOM   507   C  CB  . GLU A 1 70  ? 182.165 195.901 175.832 1.00 108.06 ? 70   GLU A CB  1 
ATOM   508   C  CG  . GLU A 1 70  ? 180.972 194.933 175.673 1.00 108.06 ? 70   GLU A CG  1 
ATOM   509   C  CD  . GLU A 1 70  ? 179.709 195.318 176.403 1.00 108.06 ? 70   GLU A CD  1 
ATOM   510   O  OE1 . GLU A 1 70  ? 179.675 196.383 177.026 1.00 108.06 ? 70   GLU A OE1 1 
ATOM   511   O  OE2 . GLU A 1 70  ? 178.733 194.537 176.349 1.00 108.06 ? 70   GLU A OE2 1 
ATOM   512   N  N   . SER A 1 71  ? 184.639 197.546 177.266 1.00 106.87 ? 71   SER A N   1 
ATOM   513   C  CA  . SER A 1 71  ? 185.985 198.105 177.169 1.00 106.87 ? 71   SER A CA  1 
ATOM   514   C  C   . SER A 1 71  ? 186.958 197.340 178.058 1.00 106.87 ? 71   SER A C   1 
ATOM   515   O  O   . SER A 1 71  ? 188.072 197.001 177.639 1.00 106.87 ? 71   SER A O   1 
ATOM   516   C  CB  . SER A 1 71  ? 185.965 199.589 177.541 1.00 106.87 ? 71   SER A CB  1 
ATOM   517   O  OG  . SER A 1 71  ? 187.267 200.143 177.486 1.00 106.87 ? 71   SER A OG  1 
ATOM   518   N  N   . ALA A 1 72  ? 186.541 197.042 179.290 1.00 105.63 ? 72   ALA A N   1 
ATOM   519   C  CA  . ALA A 1 72  ? 187.392 196.297 180.211 1.00 105.63 ? 72   ALA A CA  1 
ATOM   520   C  C   . ALA A 1 72  ? 187.629 194.875 179.720 1.00 105.63 ? 72   ALA A C   1 
ATOM   521   O  O   . ALA A 1 72  ? 188.737 194.345 179.856 1.00 105.63 ? 72   ALA A O   1 
ATOM   522   C  CB  . ALA A 1 72  ? 186.773 196.289 181.608 1.00 105.63 ? 72   ALA A CB  1 
ATOM   523   N  N   . ARG A 1 73  ? 186.598 194.235 179.161 1.00 103.07 ? 73   ARG A N   1 
ATOM   524   C  CA  . ARG A 1 73  ? 186.768 192.887 178.629 1.00 103.07 ? 73   ARG A CA  1 
ATOM   525   C  C   . ARG A 1 73  ? 187.747 192.877 177.462 1.00 103.07 ? 73   ARG A C   1 
ATOM   526   O  O   . ARG A 1 73  ? 188.576 191.968 177.344 1.00 103.07 ? 73   ARG A O   1 
ATOM   527   C  CB  . ARG A 1 73  ? 185.416 192.314 178.203 1.00 103.07 ? 73   ARG A CB  1 
ATOM   528   C  CG  . ARG A 1 73  ? 185.476 190.873 177.724 1.00 103.07 ? 73   ARG A CG  1 
ATOM   529   C  CD  . ARG A 1 73  ? 184.082 190.304 177.515 1.00 103.07 ? 73   ARG A CD  1 
ATOM   530   N  NE  . ARG A 1 73  ? 183.171 190.694 178.585 1.00 103.07 ? 73   ARG A NE  1 
ATOM   531   C  CZ  . ARG A 1 73  ? 181.861 190.489 178.565 1.00 103.07 ? 73   ARG A CZ  1 
ATOM   532   N  NH1 . ARG A 1 73  ? 181.270 189.890 177.545 1.00 103.07 ? 73   ARG A NH1 1 
ATOM   533   N  NH2 . ARG A 1 73  ? 181.126 190.895 179.597 1.00 103.07 ? 73   ARG A NH2 1 
ATOM   534   N  N   . GLU A 1 74  ? 187.662 193.879 176.585 1.00 107.39 ? 74   GLU A N   1 
ATOM   535   C  CA  . GLU A 1 74  ? 188.610 193.971 175.481 1.00 107.39 ? 74   GLU A CA  1 
ATOM   536   C  C   . GLU A 1 74  ? 190.026 194.215 175.987 1.00 107.39 ? 74   GLU A C   1 
ATOM   537   O  O   . GLU A 1 74  ? 190.987 193.642 175.461 1.00 107.39 ? 74   GLU A O   1 
ATOM   538   C  CB  . GLU A 1 74  ? 188.183 195.077 174.517 1.00 107.39 ? 74   GLU A CB  1 
ATOM   539   C  CG  . GLU A 1 74  ? 187.110 194.653 173.529 1.00 107.39 ? 74   GLU A CG  1 
ATOM   540   C  CD  . GLU A 1 74  ? 187.250 195.339 172.186 1.00 107.39 ? 74   GLU A CD  1 
ATOM   541   O  OE1 . GLU A 1 74  ? 187.757 196.479 172.150 1.00 107.39 ? 74   GLU A OE1 1 
ATOM   542   O  OE2 . GLU A 1 74  ? 186.854 194.737 171.166 1.00 107.39 ? 74   GLU A OE2 1 
ATOM   543   N  N   . GLN A 1 75  ? 190.177 195.062 177.008 1.00 106.06 ? 75   GLN A N   1 
ATOM   544   C  CA  . GLN A 1 75  ? 191.513 195.395 177.494 1.00 106.06 ? 75   GLN A CA  1 
ATOM   545   C  C   . GLN A 1 75  ? 192.155 194.224 178.230 1.00 106.06 ? 75   GLN A C   1 
ATOM   546   O  O   . GLN A 1 75  ? 193.335 193.922 178.015 1.00 106.06 ? 75   GLN A O   1 
ATOM   547   C  CB  . GLN A 1 75  ? 191.448 196.624 178.401 1.00 106.06 ? 75   GLN A CB  1 
ATOM   548   C  CG  . GLN A 1 75  ? 192.724 196.884 179.186 1.00 106.06 ? 75   GLN A CG  1 
ATOM   549   C  CD  . GLN A 1 75  ? 192.578 198.020 180.178 1.00 106.06 ? 75   GLN A CD  1 
ATOM   550   O  OE1 . GLN A 1 75  ? 191.648 198.822 180.090 1.00 106.06 ? 75   GLN A OE1 1 
ATOM   551   N  NE2 . GLN A 1 75  ? 193.499 198.095 181.131 1.00 106.06 ? 75   GLN A NE2 1 
ATOM   552   N  N   . HIS A 1 76  ? 191.401 193.550 179.096 1.00 100.98 ? 76   HIS A N   1 
ATOM   553   C  CA  . HIS A 1 76  ? 191.946 192.528 179.979 1.00 100.98 ? 76   HIS A CA  1 
ATOM   554   C  C   . HIS A 1 76  ? 191.556 191.109 179.585 1.00 100.98 ? 76   HIS A C   1 
ATOM   555   O  O   . HIS A 1 76  ? 191.807 190.179 180.358 1.00 100.98 ? 76   HIS A O   1 
ATOM   556   C  CB  . HIS A 1 76  ? 191.503 192.793 181.421 1.00 100.98 ? 76   HIS A CB  1 
ATOM   557   C  CG  . HIS A 1 76  ? 192.308 193.845 182.118 1.00 100.98 ? 76   HIS A CG  1 
ATOM   558   N  ND1 . HIS A 1 76  ? 193.586 193.620 182.581 1.00 100.98 ? 76   HIS A ND1 1 
ATOM   559   C  CD2 . HIS A 1 76  ? 192.014 195.129 182.435 1.00 100.98 ? 76   HIS A CD2 1 
ATOM   560   C  CE1 . HIS A 1 76  ? 194.046 194.719 183.151 1.00 100.98 ? 76   HIS A CE1 1 
ATOM   561   N  NE2 . HIS A 1 76  ? 193.112 195.650 183.076 1.00 100.98 ? 76   HIS A NE2 1 
ATOM   562   N  N   . GLY A 1 77  ? 190.953 190.916 178.419 1.00 99.41  ? 77   GLY A N   1 
ATOM   563   C  CA  . GLY A 1 77  ? 190.563 189.587 178.001 1.00 99.41  ? 77   GLY A CA  1 
ATOM   564   C  C   . GLY A 1 77  ? 189.295 189.108 178.684 1.00 99.41  ? 77   GLY A C   1 
ATOM   565   O  O   . GLY A 1 77  ? 188.528 189.874 179.275 1.00 99.41  ? 77   GLY A O   1 
ATOM   566   N  N   . GLU A 1 78  ? 189.082 187.799 178.595 1.00 94.64  ? 78   GLU A N   1 
ATOM   567   C  CA  . GLU A 1 78  ? 187.900 187.150 179.140 1.00 94.64  ? 78   GLU A CA  1 
ATOM   568   C  C   . GLU A 1 78  ? 188.284 186.278 180.330 1.00 94.64  ? 78   GLU A C   1 
ATOM   569   O  O   . GLU A 1 78  ? 189.418 185.802 180.433 1.00 94.64  ? 78   GLU A O   1 
ATOM   570   C  CB  . GLU A 1 78  ? 187.201 186.302 178.073 1.00 94.64  ? 78   GLU A CB  1 
ATOM   571   C  CG  . GLU A 1 78  ? 185.749 185.977 178.381 1.00 94.64  ? 78   GLU A CG  1 
ATOM   572   C  CD  . GLU A 1 78  ? 185.049 185.290 177.225 1.00 94.64  ? 78   GLU A CD  1 
ATOM   573   O  OE1 . GLU A 1 78  ? 185.717 185.003 176.210 1.00 94.64  ? 78   GLU A OE1 1 
ATOM   574   O  OE2 . GLU A 1 78  ? 183.831 185.035 177.333 1.00 94.64  ? 78   GLU A OE2 1 
ATOM   575   N  N   . ASN A 1 79  ? 187.322 186.073 181.233 1.00 88.88  ? 79   ASN A N   1 
ATOM   576   C  CA  . ASN A 1 79  ? 187.550 185.309 182.461 1.00 88.88  ? 79   ASN A CA  1 
ATOM   577   C  C   . ASN A 1 79  ? 187.504 183.810 182.155 1.00 88.88  ? 79   ASN A C   1 
ATOM   578   O  O   . ASN A 1 79  ? 186.633 183.067 182.611 1.00 88.88  ? 79   ASN A O   1 
ATOM   579   C  CB  . ASN A 1 79  ? 186.526 185.690 183.521 1.00 88.88  ? 79   ASN A CB  1 
ATOM   580   C  CG  . ASN A 1 79  ? 186.839 185.087 184.876 1.00 88.88  ? 79   ASN A CG  1 
ATOM   581   O  OD1 . ASN A 1 79  ? 188.001 184.872 185.219 1.00 88.88  ? 79   ASN A OD1 1 
ATOM   582   N  ND2 . ASN A 1 79  ? 185.800 184.812 185.656 1.00 88.88  ? 79   ASN A ND2 1 
ATOM   583   N  N   . LYS A 1 80  ? 188.483 183.368 181.369 1.00 92.03  ? 80   LYS A N   1 
ATOM   584   C  CA  . LYS A 1 80  ? 188.607 181.968 180.992 1.00 92.03  ? 80   LYS A CA  1 
ATOM   585   C  C   . LYS A 1 80  ? 190.082 181.627 180.835 1.00 92.03  ? 80   LYS A C   1 
ATOM   586   O  O   . LYS A 1 80  ? 190.932 182.506 180.662 1.00 92.03  ? 80   LYS A O   1 
ATOM   587   C  CB  . LYS A 1 80  ? 187.835 181.663 179.702 1.00 92.03  ? 80   LYS A CB  1 
ATOM   588   C  CG  . LYS A 1 80  ? 186.343 181.453 179.896 1.00 92.03  ? 80   LYS A CG  1 
ATOM   589   C  CD  . LYS A 1 80  ? 185.713 180.791 178.681 1.00 92.03  ? 80   LYS A CD  1 
ATOM   590   C  CE  . LYS A 1 80  ? 185.400 181.810 177.598 1.00 92.03  ? 80   LYS A CE  1 
ATOM   591   N  NZ  . LYS A 1 80  ? 184.254 181.379 176.750 1.00 92.03  ? 80   LYS A NZ  1 
ATOM   592   N  N   . LEU A 1 81  ? 190.381 180.341 180.894 1.00 88.90  ? 81   LEU A N   1 
ATOM   593   C  CA  . LEU A 1 81  ? 191.717 179.820 180.674 1.00 88.90  ? 81   LEU A CA  1 
ATOM   594   C  C   . LEU A 1 81  ? 192.022 179.786 179.183 1.00 88.90  ? 81   LEU A C   1 
ATOM   595   O  O   . LEU A 1 81  ? 191.107 179.759 178.355 1.00 88.90  ? 81   LEU A O   1 
ATOM   596   C  CB  . LEU A 1 81  ? 191.841 178.411 181.267 1.00 88.90  ? 81   LEU A CB  1 
ATOM   597   C  CG  . LEU A 1 81  ? 192.296 178.261 182.725 1.00 88.90  ? 81   LEU A CG  1 
ATOM   598   C  CD1 . LEU A 1 81  ? 193.770 178.610 182.884 1.00 88.90  ? 81   LEU A CD1 1 
ATOM   599   C  CD2 . LEU A 1 81  ? 191.440 179.089 183.675 1.00 88.90  ? 81   LEU A CD2 1 
ATOM   600   N  N   . PRO A 1 82  ? 193.302 179.795 178.798 1.00 86.89  ? 82   PRO A N   1 
ATOM   601   C  CA  . PRO A 1 82  ? 193.630 179.782 177.362 1.00 86.89  ? 82   PRO A CA  1 
ATOM   602   C  C   . PRO A 1 82  ? 193.133 178.549 176.629 1.00 86.89  ? 82   PRO A C   1 
ATOM   603   O  O   . PRO A 1 82  ? 193.013 178.586 175.398 1.00 86.89  ? 82   PRO A O   1 
ATOM   604   C  CB  . PRO A 1 82  ? 195.164 179.862 177.350 1.00 86.89  ? 82   PRO A CB  1 
ATOM   605   C  CG  . PRO A 1 82  ? 195.583 179.411 178.712 1.00 86.89  ? 82   PRO A CG  1 
ATOM   606   C  CD  . PRO A 1 82  ? 194.512 179.915 179.627 1.00 86.89  ? 82   PRO A CD  1 
ATOM   607   N  N   . ALA A 1 83  ? 192.838 177.462 177.338 1.00 86.42  ? 83   ALA A N   1 
ATOM   608   C  CA  . ALA A 1 83  ? 192.337 176.242 176.723 1.00 86.42  ? 83   ALA A CA  1 
ATOM   609   C  C   . ALA A 1 83  ? 190.817 176.201 176.624 1.00 86.42  ? 83   ALA A C   1 
ATOM   610   O  O   . ALA A 1 83  ? 190.269 175.188 176.178 1.00 86.42  ? 83   ALA A O   1 
ATOM   611   C  CB  . ALA A 1 83  ? 192.832 175.019 177.502 1.00 86.42  ? 83   ALA A CB  1 
ATOM   612   N  N   . GLN A 1 84  ? 190.126 177.269 177.022 1.00 83.72  ? 84   GLN A N   1 
ATOM   613   C  CA  . GLN A 1 84  ? 188.670 177.287 177.045 1.00 83.72  ? 84   GLN A CA  1 
ATOM   614   C  C   . GLN A 1 84  ? 188.053 178.132 175.939 1.00 83.72  ? 84   GLN A C   1 
ATOM   615   O  O   . GLN A 1 84  ? 186.825 178.139 175.801 1.00 83.72  ? 84   GLN A O   1 
ATOM   616   C  CB  . GLN A 1 84  ? 188.172 177.788 178.407 1.00 83.72  ? 84   GLN A CB  1 
ATOM   617   C  CG  . GLN A 1 84  ? 188.271 176.763 179.524 1.00 83.72  ? 84   GLN A CG  1 
ATOM   618   C  CD  . GLN A 1 84  ? 187.296 175.616 179.350 1.00 83.72  ? 84   GLN A CD  1 
ATOM   619   O  OE1 . GLN A 1 84  ? 186.187 175.799 178.847 1.00 83.72  ? 84   GLN A OE1 1 
ATOM   620   N  NE2 . GLN A 1 84  ? 187.704 174.425 179.769 1.00 83.72  ? 84   GLN A NE2 1 
ATOM   621   N  N   . GLN A 1 85  ? 188.857 178.842 175.150 1.00 85.22  ? 85   GLN A N   1 
ATOM   622   C  CA  . GLN A 1 85  ? 188.321 179.669 174.077 1.00 85.22  ? 85   GLN A CA  1 
ATOM   623   C  C   . GLN A 1 85  ? 188.175 178.839 172.810 1.00 85.22  ? 85   GLN A C   1 
ATOM   624   O  O   . GLN A 1 85  ? 189.186 178.357 172.281 1.00 85.22  ? 85   GLN A O   1 
ATOM   625   C  CB  . GLN A 1 85  ? 189.221 180.864 173.809 1.00 85.22  ? 85   GLN A CB  1 
ATOM   626   C  CG  . GLN A 1 85  ? 189.115 181.969 174.843 1.00 85.22  ? 85   GLN A CG  1 
ATOM   627   C  CD  . GLN A 1 85  ? 190.118 181.808 175.963 1.00 85.22  ? 85   GLN A CD  1 
ATOM   628   O  OE1 . GLN A 1 85  ? 191.068 181.035 175.852 1.00 85.22  ? 85   GLN A OE1 1 
ATOM   629   N  NE2 . GLN A 1 85  ? 189.914 182.540 177.052 1.00 85.22  ? 85   GLN A NE2 1 
ATOM   630   N  N   . PRO A 1 86  ? 186.964 178.642 172.298 1.00 76.83  ? 86   PRO A N   1 
ATOM   631   C  CA  . PRO A 1 86  ? 186.811 177.917 171.034 1.00 76.83  ? 86   PRO A CA  1 
ATOM   632   C  C   . PRO A 1 86  ? 187.390 178.701 169.868 1.00 76.83  ? 86   PRO A C   1 
ATOM   633   O  O   . PRO A 1 86  ? 187.377 179.934 169.845 1.00 76.83  ? 86   PRO A O   1 
ATOM   634   C  CB  . PRO A 1 86  ? 185.293 177.755 170.897 1.00 76.83  ? 86   PRO A CB  1 
ATOM   635   C  CG  . PRO A 1 86  ? 184.721 178.868 171.707 1.00 76.83  ? 86   PRO A CG  1 
ATOM   636   C  CD  . PRO A 1 86  ? 185.672 179.086 172.848 1.00 76.83  ? 86   PRO A CD  1 
ATOM   637   N  N   . SER A 1 87  ? 187.906 177.963 168.892 1.00 79.70  ? 87   SER A N   1 
ATOM   638   C  CA  . SER A 1 87  ? 188.470 178.567 167.697 1.00 79.70  ? 87   SER A CA  1 
ATOM   639   C  C   . SER A 1 87  ? 187.359 179.080 166.781 1.00 79.70  ? 87   SER A C   1 
ATOM   640   O  O   . SER A 1 87  ? 186.228 178.588 166.830 1.00 79.70  ? 87   SER A O   1 
ATOM   641   C  CB  . SER A 1 87  ? 189.332 177.556 166.949 1.00 79.70  ? 87   SER A CB  1 
ATOM   642   O  OG  . SER A 1 87  ? 188.535 176.703 166.147 1.00 79.70  ? 87   SER A OG  1 
ATOM   643   N  N   . PRO A 1 88  ? 187.653 180.074 165.944 1.00 81.93  ? 88   PRO A N   1 
ATOM   644   C  CA  . PRO A 1 88  ? 186.648 180.548 164.986 1.00 81.93  ? 88   PRO A CA  1 
ATOM   645   C  C   . PRO A 1 88  ? 186.300 179.476 163.966 1.00 81.93  ? 88   PRO A C   1 
ATOM   646   O  O   . PRO A 1 88  ? 187.095 178.578 163.674 1.00 81.93  ? 88   PRO A O   1 
ATOM   647   C  CB  . PRO A 1 88  ? 187.322 181.754 164.319 1.00 81.93  ? 88   PRO A CB  1 
ATOM   648   C  CG  . PRO A 1 88  ? 188.456 182.126 165.213 1.00 81.93  ? 88   PRO A CG  1 
ATOM   649   C  CD  . PRO A 1 88  ? 188.887 180.876 165.904 1.00 81.93  ? 88   PRO A CD  1 
ATOM   650   N  N   . TRP A 1 89  ? 185.083 179.580 163.424 1.00 84.75  ? 89   TRP A N   1 
ATOM   651   C  CA  . TRP A 1 89  ? 184.578 178.547 162.526 1.00 84.75  ? 89   TRP A CA  1 
ATOM   652   C  C   . TRP A 1 89  ? 185.416 178.432 161.259 1.00 84.75  ? 89   TRP A C   1 
ATOM   653   O  O   . TRP A 1 89  ? 185.646 177.319 160.769 1.00 84.75  ? 89   TRP A O   1 
ATOM   654   C  CB  . TRP A 1 89  ? 183.112 178.821 162.181 1.00 84.75  ? 89   TRP A CB  1 
ATOM   655   C  CG  . TRP A 1 89  ? 182.891 180.037 161.334 1.00 84.75  ? 89   TRP A CG  1 
ATOM   656   C  CD1 . TRP A 1 89  ? 182.651 181.307 161.771 1.00 84.75  ? 89   TRP A CD1 1 
ATOM   657   C  CD2 . TRP A 1 89  ? 182.871 180.095 159.902 1.00 84.75  ? 89   TRP A CD2 1 
ATOM   658   N  NE1 . TRP A 1 89  ? 182.494 182.154 160.700 1.00 84.75  ? 89   TRP A NE1 1 
ATOM   659   C  CE2 . TRP A 1 89  ? 182.624 181.434 159.542 1.00 84.75  ? 89   TRP A CE2 1 
ATOM   660   C  CE3 . TRP A 1 89  ? 183.045 179.145 158.891 1.00 84.75  ? 89   TRP A CE3 1 
ATOM   661   C  CZ2 . TRP A 1 89  ? 182.544 181.847 158.214 1.00 84.75  ? 89   TRP A CZ2 1 
ATOM   662   C  CZ3 . TRP A 1 89  ? 182.965 179.557 157.573 1.00 84.75  ? 89   TRP A CZ3 1 
ATOM   663   C  CH2 . TRP A 1 89  ? 182.717 180.896 157.247 1.00 84.75  ? 89   TRP A CH2 1 
ATOM   664   N  N   . TRP A 1 90  ? 185.877 179.558 160.708 1.00 83.18  ? 90   TRP A N   1 
ATOM   665   C  CA  . TRP A 1 90  ? 186.709 179.491 159.512 1.00 83.18  ? 90   TRP A CA  1 
ATOM   666   C  C   . TRP A 1 90  ? 188.055 178.840 159.804 1.00 83.18  ? 90   TRP A C   1 
ATOM   667   O  O   . TRP A 1 90  ? 188.584 178.111 158.957 1.00 83.18  ? 90   TRP A O   1 
ATOM   668   C  CB  . TRP A 1 90  ? 186.894 180.885 158.910 1.00 83.18  ? 90   TRP A CB  1 
ATOM   669   C  CG  . TRP A 1 90  ? 187.669 181.842 159.764 1.00 83.18  ? 90   TRP A CG  1 
ATOM   670   C  CD1 . TRP A 1 90  ? 189.026 181.955 159.846 1.00 83.18  ? 90   TRP A CD1 1 
ATOM   671   C  CD2 . TRP A 1 90  ? 187.130 182.835 160.644 1.00 83.18  ? 90   TRP A CD2 1 
ATOM   672   N  NE1 . TRP A 1 90  ? 189.366 182.951 160.729 1.00 83.18  ? 90   TRP A NE1 1 
ATOM   673   C  CE2 . TRP A 1 90  ? 188.220 183.507 161.233 1.00 83.18  ? 90   TRP A CE2 1 
ATOM   674   C  CE3 . TRP A 1 90  ? 185.833 183.219 160.995 1.00 83.18  ? 90   TRP A CE3 1 
ATOM   675   C  CZ2 . TRP A 1 90  ? 188.052 184.540 162.152 1.00 83.18  ? 90   TRP A CZ2 1 
ATOM   676   C  CZ3 . TRP A 1 90  ? 185.668 184.245 161.908 1.00 83.18  ? 90   TRP A CZ3 1 
ATOM   677   C  CH2 . TRP A 1 90  ? 186.772 184.893 162.475 1.00 83.18  ? 90   TRP A CH2 1 
ATOM   678   N  N   . VAL A 1 91  ? 188.616 179.075 160.992 1.00 80.30  ? 91   VAL A N   1 
ATOM   679   C  CA  . VAL A 1 91  ? 189.848 178.393 161.378 1.00 80.30  ? 91   VAL A CA  1 
ATOM   680   C  C   . VAL A 1 91  ? 189.619 176.891 161.469 1.00 80.30  ? 91   VAL A C   1 
ATOM   681   O  O   . VAL A 1 91  ? 190.463 176.093 161.043 1.00 80.30  ? 91   VAL A O   1 
ATOM   682   C  CB  . VAL A 1 91  ? 190.387 178.962 162.702 1.00 80.30  ? 91   VAL A CB  1 
ATOM   683   C  CG1 . VAL A 1 91  ? 191.731 178.335 163.040 1.00 80.30  ? 91   VAL A CG1 1 
ATOM   684   C  CG2 . VAL A 1 91  ? 190.510 180.472 162.619 1.00 80.30  ? 91   VAL A CG2 1 
ATOM   685   N  N   . HIS A 1 92  ? 188.483 176.481 162.037 1.00 76.67  ? 92   HIS A N   1 
ATOM   686   C  CA  . HIS A 1 92  ? 188.167 175.058 162.123 1.00 76.67  ? 92   HIS A CA  1 
ATOM   687   C  C   . HIS A 1 92  ? 188.016 174.445 160.736 1.00 76.67  ? 92   HIS A C   1 
ATOM   688   O  O   . HIS A 1 92  ? 188.509 173.340 160.479 1.00 76.67  ? 92   HIS A O   1 
ATOM   689   C  CB  . HIS A 1 92  ? 186.896 174.855 162.945 1.00 76.67  ? 92   HIS A CB  1 
ATOM   690   C  CG  . HIS A 1 92  ? 186.596 173.421 163.250 1.00 76.67  ? 92   HIS A CG  1 
ATOM   691   N  ND1 . HIS A 1 92  ? 187.584 172.480 163.441 1.00 76.67  ? 92   HIS A ND1 1 
ATOM   692   C  CD2 . HIS A 1 92  ? 185.420 172.768 163.398 1.00 76.67  ? 92   HIS A CD2 1 
ATOM   693   C  CE1 . HIS A 1 92  ? 187.030 171.308 163.693 1.00 76.67  ? 92   HIS A CE1 1 
ATOM   694   N  NE2 . HIS A 1 92  ? 185.717 171.455 163.673 1.00 76.67  ? 92   HIS A NE2 1 
ATOM   695   N  N   . LEU A 1 93  ? 187.341 175.151 159.827 1.00 77.49  ? 93   LEU A N   1 
ATOM   696   C  CA  . LEU A 1 93  ? 187.205 174.657 158.460 1.00 77.49  ? 93   LEU A CA  1 
ATOM   697   C  C   . LEU A 1 93  ? 188.562 174.529 157.781 1.00 77.49  ? 93   LEU A C   1 
ATOM   698   O  O   . LEU A 1 93  ? 188.832 173.535 157.095 1.00 77.49  ? 93   LEU A O   1 
ATOM   699   C  CB  . LEU A 1 93  ? 186.288 175.582 157.661 1.00 77.49  ? 93   LEU A CB  1 
ATOM   700   C  CG  . LEU A 1 93  ? 186.017 175.197 156.206 1.00 77.49  ? 93   LEU A CG  1 
ATOM   701   C  CD1 . LEU A 1 93  ? 185.387 173.819 156.117 1.00 77.49  ? 93   LEU A CD1 1 
ATOM   702   C  CD2 . LEU A 1 93  ? 185.131 176.238 155.540 1.00 77.49  ? 93   LEU A CD2 1 
ATOM   703   N  N   . TRP A 1 94  ? 189.432 175.525 157.963 1.00 81.47  ? 94   TRP A N   1 
ATOM   704   C  CA  . TRP A 1 94  ? 190.757 175.469 157.355 1.00 81.47  ? 94   TRP A CA  1 
ATOM   705   C  C   . TRP A 1 94  ? 191.575 174.309 157.906 1.00 81.47  ? 94   TRP A C   1 
ATOM   706   O  O   . TRP A 1 94  ? 192.234 173.590 157.146 1.00 81.47  ? 94   TRP A O   1 
ATOM   707   C  CB  . TRP A 1 94  ? 191.492 176.791 157.569 1.00 81.47  ? 94   TRP A CB  1 
ATOM   708   C  CG  . TRP A 1 94  ? 192.934 176.738 157.172 1.00 81.47  ? 94   TRP A CG  1 
ATOM   709   C  CD1 . TRP A 1 94  ? 194.016 176.885 157.990 1.00 81.47  ? 94   TRP A CD1 1 
ATOM   710   C  CD2 . TRP A 1 94  ? 193.455 176.511 155.856 1.00 81.47  ? 94   TRP A CD2 1 
ATOM   711   N  NE1 . TRP A 1 94  ? 195.177 176.770 157.266 1.00 81.47  ? 94   TRP A NE1 1 
ATOM   712   C  CE2 . TRP A 1 94  ? 194.860 176.540 155.953 1.00 81.47  ? 94   TRP A CE2 1 
ATOM   713   C  CE3 . TRP A 1 94  ? 192.869 176.290 154.606 1.00 81.47  ? 94   TRP A CE3 1 
ATOM   714   C  CZ2 . TRP A 1 94  ? 195.688 176.355 154.848 1.00 81.47  ? 94   TRP A CZ2 1 
ATOM   715   C  CZ3 . TRP A 1 94  ? 193.693 176.107 153.510 1.00 81.47  ? 94   TRP A CZ3 1 
ATOM   716   C  CH2 . TRP A 1 94  ? 195.087 176.141 153.639 1.00 81.47  ? 94   TRP A CH2 1 
ATOM   717   N  N   . VAL A 1 95  ? 191.547 174.107 159.226 1.00 76.80  ? 95   VAL A N   1 
ATOM   718   C  CA  . VAL A 1 95  ? 192.333 173.024 159.810 1.00 76.80  ? 95   VAL A CA  1 
ATOM   719   C  C   . VAL A 1 95  ? 191.758 171.668 159.416 1.00 76.80  ? 95   VAL A C   1 
ATOM   720   O  O   . VAL A 1 95  ? 192.497 170.681 159.319 1.00 76.80  ? 95   VAL A O   1 
ATOM   721   C  CB  . VAL A 1 95  ? 192.441 173.188 161.340 1.00 76.80  ? 95   VAL A CB  1 
ATOM   722   C  CG1 . VAL A 1 95  ? 191.151 172.786 162.035 1.00 76.80  ? 95   VAL A CG1 1 
ATOM   723   C  CG2 . VAL A 1 95  ? 193.616 172.385 161.878 1.00 76.80  ? 95   VAL A CG2 1 
ATOM   724   N  N   . CYS A 1 96  ? 190.445 171.588 159.184 1.00 77.15  ? 96   CYS A N   1 
ATOM   725   C  CA  . CYS A 1 96  ? 189.874 170.362 158.638 1.00 77.15  ? 96   CYS A CA  1 
ATOM   726   C  C   . CYS A 1 96  ? 190.351 170.123 157.211 1.00 77.15  ? 96   CYS A C   1 
ATOM   727   O  O   . CYS A 1 96  ? 190.665 168.987 156.836 1.00 77.15  ? 96   CYS A O   1 
ATOM   728   C  CB  . CYS A 1 96  ? 188.348 170.421 158.691 1.00 77.15  ? 96   CYS A CB  1 
ATOM   729   S  SG  . CYS A 1 96  ? 187.643 170.159 160.334 1.00 77.15  ? 96   CYS A SG  1 
ATOM   730   N  N   . TYR A 1 97  ? 190.412 171.182 156.403 1.00 82.23  ? 97   TYR A N   1 
ATOM   731   C  CA  . TYR A 1 97  ? 190.825 171.042 155.011 1.00 82.23  ? 97   TYR A CA  1 
ATOM   732   C  C   . TYR A 1 97  ? 192.333 170.869 154.864 1.00 82.23  ? 97   TYR A C   1 
ATOM   733   O  O   . TYR A 1 97  ? 192.787 170.257 153.891 1.00 82.23  ? 97   TYR A O   1 
ATOM   734   C  CB  . TYR A 1 97  ? 190.358 172.254 154.203 1.00 82.23  ? 97   TYR A CB  1 
ATOM   735   C  CG  . TYR A 1 97  ? 190.530 172.106 152.709 1.00 82.23  ? 97   TYR A CG  1 
ATOM   736   C  CD1 . TYR A 1 97  ? 189.581 171.440 151.944 1.00 82.23  ? 97   TYR A CD1 1 
ATOM   737   C  CD2 . TYR A 1 97  ? 191.639 172.635 152.062 1.00 82.23  ? 97   TYR A CD2 1 
ATOM   738   C  CE1 . TYR A 1 97  ? 189.734 171.303 150.577 1.00 82.23  ? 97   TYR A CE1 1 
ATOM   739   C  CE2 . TYR A 1 97  ? 191.800 172.502 150.696 1.00 82.23  ? 97   TYR A CE2 1 
ATOM   740   C  CZ  . TYR A 1 97  ? 190.845 171.836 149.958 1.00 82.23  ? 97   TYR A CZ  1 
ATOM   741   O  OH  . TYR A 1 97  ? 191.002 171.702 148.598 1.00 82.23  ? 97   TYR A OH  1 
ATOM   742   N  N   . ARG A 1 98  ? 193.118 171.390 155.806 1.00 83.52  ? 98   ARG A N   1 
ATOM   743   C  CA  . ARG A 1 98  ? 194.572 171.396 155.693 1.00 83.52  ? 98   ARG A CA  1 
ATOM   744   C  C   . ARG A 1 98  ? 195.202 170.037 156.002 1.00 83.52  ? 98   ARG A C   1 
ATOM   745   O  O   . ARG A 1 98  ? 196.432 169.940 156.072 1.00 83.52  ? 98   ARG A O   1 
ATOM   746   C  CB  . ARG A 1 98  ? 195.160 172.470 156.617 1.00 83.52  ? 98   ARG A CB  1 
ATOM   747   C  CG  . ARG A 1 98  ? 196.564 172.938 156.245 1.00 83.52  ? 98   ARG A CG  1 
ATOM   748   C  CD  . ARG A 1 98  ? 197.071 174.004 157.201 1.00 83.52  ? 98   ARG A CD  1 
ATOM   749   N  NE  . ARG A 1 98  ? 197.290 173.477 158.542 1.00 83.52  ? 98   ARG A NE  1 
ATOM   750   C  CZ  . ARG A 1 98  ? 197.586 174.220 159.600 1.00 83.52  ? 98   ARG A CZ  1 
ATOM   751   N  NH1 . ARG A 1 98  ? 197.704 175.534 159.510 1.00 83.52  ? 98   ARG A NH1 1 
ATOM   752   N  NH2 . ARG A 1 98  ? 197.768 173.629 160.777 1.00 83.52  ? 98   ARG A NH2 1 
ATOM   753   N  N   . ASN A 1 99  ? 194.400 168.990 156.182 1.00 80.13  ? 99   ASN A N   1 
ATOM   754   C  CA  . ASN A 1 99  ? 194.956 167.685 156.498 1.00 80.13  ? 99   ASN A CA  1 
ATOM   755   C  C   . ASN A 1 99  ? 195.781 167.151 155.326 1.00 80.13  ? 99   ASN A C   1 
ATOM   756   O  O   . ASN A 1 99  ? 195.531 167.500 154.169 1.00 80.13  ? 99   ASN A O   1 
ATOM   757   C  CB  . ASN A 1 99  ? 193.845 166.702 156.872 1.00 80.13  ? 99   ASN A CB  1 
ATOM   758   C  CG  . ASN A 1 99  ? 192.800 166.545 155.786 1.00 80.13  ? 99   ASN A CG  1 
ATOM   759   O  OD1 . ASN A 1 99  ? 192.922 167.103 154.699 1.00 80.13  ? 99   ASN A OD1 1 
ATOM   760   N  ND2 . ASN A 1 99  ? 191.759 165.775 156.080 1.00 80.13  ? 99   ASN A ND2 1 
ATOM   761   N  N   . PRO A 1 100 ? 196.797 166.330 155.605 1.00 80.89  ? 100  PRO A N   1 
ATOM   762   C  CA  . PRO A 1 100 ? 197.667 165.848 154.521 1.00 80.89  ? 100  PRO A CA  1 
ATOM   763   C  C   . PRO A 1 100 ? 196.941 165.050 153.455 1.00 80.89  ? 100  PRO A C   1 
ATOM   764   O  O   . PRO A 1 100 ? 197.322 165.120 152.280 1.00 80.89  ? 100  PRO A O   1 
ATOM   765   C  CB  . PRO A 1 100 ? 198.699 164.986 155.262 1.00 80.89  ? 100  PRO A CB  1 
ATOM   766   C  CG  . PRO A 1 100 ? 198.689 165.504 156.662 1.00 80.89  ? 100  PRO A CG  1 
ATOM   767   C  CD  . PRO A 1 100 ? 197.266 165.880 156.927 1.00 80.89  ? 100  PRO A CD  1 
ATOM   768   N  N   . PHE A 1 101 ? 195.907 164.291 153.824 1.00 80.60  ? 101  PHE A N   1 
ATOM   769   C  CA  . PHE A 1 101 ? 195.272 163.389 152.867 1.00 80.60  ? 101  PHE A CA  1 
ATOM   770   C  C   . PHE A 1 101 ? 194.562 164.156 151.758 1.00 80.60  ? 101  PHE A C   1 
ATOM   771   O  O   . PHE A 1 101 ? 194.739 163.853 150.574 1.00 80.60  ? 101  PHE A O   1 
ATOM   772   C  CB  . PHE A 1 101 ? 194.302 162.459 153.593 1.00 80.60  ? 101  PHE A CB  1 
ATOM   773   C  CG  . PHE A 1 101 ? 194.944 161.661 154.686 1.00 80.60  ? 101  PHE A CG  1 
ATOM   774   C  CD1 . PHE A 1 101 ? 195.924 160.729 154.392 1.00 80.60  ? 101  PHE A CD1 1 
ATOM   775   C  CD2 . PHE A 1 101 ? 194.579 161.850 156.007 1.00 80.60  ? 101  PHE A CD2 1 
ATOM   776   C  CE1 . PHE A 1 101 ? 196.524 159.996 155.394 1.00 80.60  ? 101  PHE A CE1 1 
ATOM   777   C  CE2 . PHE A 1 101 ? 195.176 161.120 157.014 1.00 80.60  ? 101  PHE A CE2 1 
ATOM   778   C  CZ  . PHE A 1 101 ? 196.149 160.190 156.707 1.00 80.60  ? 101  PHE A CZ  1 
ATOM   779   N  N   . ASN A 1 102 ? 193.753 165.155 152.120 1.00 78.38  ? 102  ASN A N   1 
ATOM   780   C  CA  . ASN A 1 102 ? 193.019 165.905 151.104 1.00 78.38  ? 102  ASN A CA  1 
ATOM   781   C  C   . ASN A 1 102 ? 193.960 166.724 150.228 1.00 78.38  ? 102  ASN A C   1 
ATOM   782   O  O   . ASN A 1 102 ? 193.770 166.806 149.008 1.00 78.38  ? 102  ASN A O   1 
ATOM   783   C  CB  . ASN A 1 102 ? 191.980 166.806 151.766 1.00 78.38  ? 102  ASN A CB  1 
ATOM   784   C  CG  . ASN A 1 102 ? 190.833 166.023 152.371 1.00 78.38  ? 102  ASN A CG  1 
ATOM   785   O  OD1 . ASN A 1 102 ? 190.431 166.268 153.508 1.00 78.38  ? 102  ASN A OD1 1 
ATOM   786   N  ND2 . ASN A 1 102 ? 190.307 165.064 151.618 1.00 78.38  ? 102  ASN A ND2 1 
ATOM   787   N  N   . ILE A 1 103 ? 194.977 167.339 150.834 1.00 77.76  ? 103  ILE A N   1 
ATOM   788   C  CA  . ILE A 1 103 ? 195.944 168.118 150.065 1.00 77.76  ? 103  ILE A CA  1 
ATOM   789   C  C   . ILE A 1 103 ? 196.689 167.219 149.088 1.00 77.76  ? 103  ILE A C   1 
ATOM   790   O  O   . ILE A 1 103 ? 196.881 167.571 147.916 1.00 77.76  ? 103  ILE A O   1 
ATOM   791   C  CB  . ILE A 1 103 ? 196.909 168.852 151.014 1.00 77.76  ? 103  ILE A CB  1 
ATOM   792   C  CG1 . ILE A 1 103 ? 196.228 170.081 151.617 1.00 77.76  ? 103  ILE A CG1 1 
ATOM   793   C  CG2 . ILE A 1 103 ? 198.184 169.251 150.285 1.00 77.76  ? 103  ILE A CG2 1 
ATOM   794   C  CD1 . ILE A 1 103 ? 197.103 170.855 152.577 1.00 77.76  ? 103  ILE A CD1 1 
ATOM   795   N  N   . LEU A 1 104 ? 197.117 166.044 149.552 1.00 73.95  ? 104  LEU A N   1 
ATOM   796   C  CA  . LEU A 1 104 ? 197.810 165.108 148.676 1.00 73.95  ? 104  LEU A CA  1 
ATOM   797   C  C   . LEU A 1 104 ? 196.891 164.600 147.572 1.00 73.95  ? 104  LEU A C   1 
ATOM   798   O  O   . LEU A 1 104 ? 197.328 164.422 146.432 1.00 73.95  ? 104  LEU A O   1 
ATOM   799   C  CB  . LEU A 1 104 ? 198.372 163.945 149.492 1.00 73.95  ? 104  LEU A CB  1 
ATOM   800   C  CG  . LEU A 1 104 ? 199.593 163.240 148.900 1.00 73.95  ? 104  LEU A CG  1 
ATOM   801   C  CD1 . LEU A 1 104 ? 200.739 164.222 148.714 1.00 73.95  ? 104  LEU A CD1 1 
ATOM   802   C  CD2 . LEU A 1 104 ? 200.017 162.076 149.781 1.00 73.95  ? 104  LEU A CD2 1 
ATOM   803   N  N   . LEU A 1 105 ? 195.616 164.363 147.890 1.00 74.52  ? 105  LEU A N   1 
ATOM   804   C  CA  . LEU A 1 105 ? 194.659 163.951 146.869 1.00 74.52  ? 105  LEU A CA  1 
ATOM   805   C  C   . LEU A 1 105 ? 194.515 165.016 145.792 1.00 74.52  ? 105  LEU A C   1 
ATOM   806   O  O   . LEU A 1 105 ? 194.520 164.710 144.595 1.00 74.52  ? 105  LEU A O   1 
ATOM   807   C  CB  . LEU A 1 105 ? 193.301 163.654 147.506 1.00 74.52  ? 105  LEU A CB  1 
ATOM   808   C  CG  . LEU A 1 105 ? 192.986 162.213 147.904 1.00 74.52  ? 105  LEU A CG  1 
ATOM   809   C  CD1 . LEU A 1 105 ? 191.518 162.093 148.272 1.00 74.52  ? 105  LEU A CD1 1 
ATOM   810   C  CD2 . LEU A 1 105 ? 193.335 161.256 146.778 1.00 74.52  ? 105  LEU A CD2 1 
ATOM   811   N  N   . THR A 1 106 ? 194.383 166.279 146.201 1.00 79.11  ? 106  THR A N   1 
ATOM   812   C  CA  . THR A 1 106 ? 194.244 167.358 145.227 1.00 79.11  ? 106  THR A CA  1 
ATOM   813   C  C   . THR A 1 106 ? 195.504 167.504 144.379 1.00 79.11  ? 106  THR A C   1 
ATOM   814   O  O   . THR A 1 106 ? 195.424 167.687 143.157 1.00 79.11  ? 106  THR A O   1 
ATOM   815   C  CB  . THR A 1 106 ? 193.920 168.669 145.942 1.00 79.11  ? 106  THR A CB  1 
ATOM   816   O  OG1 . THR A 1 106 ? 192.689 168.528 146.663 1.00 79.11  ? 106  THR A OG1 1 
ATOM   817   C  CG2 . THR A 1 106 ? 193.781 169.803 144.939 1.00 79.11  ? 106  THR A CG2 1 
ATOM   818   N  N   . ILE A 1 107 ? 196.677 167.420 145.010 1.00 77.72  ? 107  ILE A N   1 
ATOM   819   C  CA  . ILE A 1 107 ? 197.931 167.560 144.276 1.00 77.72  ? 107  ILE A CA  1 
ATOM   820   C  C   . ILE A 1 107 ? 198.093 166.420 143.277 1.00 77.72  ? 107  ILE A C   1 
ATOM   821   O  O   . ILE A 1 107 ? 198.479 166.635 142.121 1.00 77.72  ? 107  ILE A O   1 
ATOM   822   C  CB  . ILE A 1 107 ? 199.117 167.632 145.255 1.00 77.72  ? 107  ILE A CB  1 
ATOM   823   C  CG1 . ILE A 1 107 ? 199.195 169.021 145.891 1.00 77.72  ? 107  ILE A CG1 1 
ATOM   824   C  CG2 . ILE A 1 107 ? 200.421 167.295 144.549 1.00 77.72  ? 107  ILE A CG2 1 
ATOM   825   C  CD1 . ILE A 1 107 ? 200.345 169.186 146.860 1.00 77.72  ? 107  ILE A CD1 1 
ATOM   826   N  N   . LEU A 1 108 ? 197.795 165.190 143.705 1.00 80.55  ? 108  LEU A N   1 
ATOM   827   C  CA  . LEU A 1 108 ? 197.879 164.049 142.803 1.00 80.55  ? 108  LEU A CA  1 
ATOM   828   C  C   . LEU A 1 108 ? 196.863 164.150 141.676 1.00 80.55  ? 108  LEU A C   1 
ATOM   829   O  O   . LEU A 1 108 ? 197.166 163.766 140.543 1.00 80.55  ? 108  LEU A O   1 
ATOM   830   C  CB  . LEU A 1 108 ? 197.685 162.747 143.579 1.00 80.55  ? 108  LEU A CB  1 
ATOM   831   C  CG  . LEU A 1 108 ? 198.854 162.316 144.466 1.00 80.55  ? 108  LEU A CG  1 
ATOM   832   C  CD1 . LEU A 1 108 ? 198.609 160.931 145.039 1.00 80.55  ? 108  LEU A CD1 1 
ATOM   833   C  CD2 . LEU A 1 108 ? 200.162 162.353 143.692 1.00 80.55  ? 108  LEU A CD2 1 
ATOM   834   N  N   . GLY A 1 109 ? 195.661 164.654 141.959 1.00 83.68  ? 109  GLY A N   1 
ATOM   835   C  CA  . GLY A 1 109 ? 194.695 164.867 140.896 1.00 83.68  ? 109  GLY A CA  1 
ATOM   836   C  C   . GLY A 1 109 ? 195.189 165.855 139.861 1.00 83.68  ? 109  GLY A C   1 
ATOM   837   O  O   . GLY A 1 109 ? 195.098 165.606 138.655 1.00 83.68  ? 109  GLY A O   1 
ATOM   838   N  N   . ALA A 1 110 ? 195.734 166.984 140.319 1.00 85.52  ? 110  ALA A N   1 
ATOM   839   C  CA  . ALA A 1 110 ? 196.271 167.972 139.390 1.00 85.52  ? 110  ALA A CA  1 
ATOM   840   C  C   . ALA A 1 110 ? 197.411 167.388 138.565 1.00 85.52  ? 110  ALA A C   1 
ATOM   841   O  O   . ALA A 1 110 ? 197.474 167.593 137.348 1.00 85.52  ? 110  ALA A O   1 
ATOM   842   C  CB  . ALA A 1 110 ? 196.737 169.212 140.152 1.00 85.52  ? 110  ALA A CB  1 
ATOM   843   N  N   . ILE A 1 111 ? 198.311 166.641 139.208 1.00 84.72  ? 111  ILE A N   1 
ATOM   844   C  CA  . ILE A 1 111 ? 199.442 166.060 138.491 1.00 84.72  ? 111  ILE A CA  1 
ATOM   845   C  C   . ILE A 1 111 ? 198.966 165.036 137.465 1.00 84.72  ? 111  ILE A C   1 
ATOM   846   O  O   . ILE A 1 111 ? 199.431 165.023 136.319 1.00 84.72  ? 111  ILE A O   1 
ATOM   847   C  CB  . ILE A 1 111 ? 200.440 165.443 139.487 1.00 84.72  ? 111  ILE A CB  1 
ATOM   848   C  CG1 . ILE A 1 111 ? 201.186 166.543 140.244 1.00 84.72  ? 111  ILE A CG1 1 
ATOM   849   C  CG2 . ILE A 1 111 ? 201.427 164.541 138.768 1.00 84.72  ? 111  ILE A CG2 1 
ATOM   850   C  CD1 . ILE A 1 111 ? 202.121 166.018 141.311 1.00 84.72  ? 111  ILE A CD1 1 
ATOM   851   N  N   . SER A 1 112 ? 198.028 164.169 137.854 1.00 88.33  ? 112  SER A N   1 
ATOM   852   C  CA  . SER A 1 112 ? 197.614 163.076 136.982 1.00 88.33  ? 112  SER A CA  1 
ATOM   853   C  C   . SER A 1 112 ? 196.771 163.573 135.814 1.00 88.33  ? 112  SER A C   1 
ATOM   854   O  O   . SER A 1 112 ? 196.892 163.059 134.697 1.00 88.33  ? 112  SER A O   1 
ATOM   855   C  CB  . SER A 1 112 ? 196.846 162.030 137.788 1.00 88.33  ? 112  SER A CB  1 
ATOM   856   O  OG  . SER A 1 112 ? 197.723 161.277 138.606 1.00 88.33  ? 112  SER A OG  1 
ATOM   857   N  N   . TYR A 1 113 ? 195.911 164.567 136.045 1.00 92.01  ? 113  TYR A N   1 
ATOM   858   C  CA  . TYR A 1 113 ? 195.008 165.054 135.011 1.00 92.01  ? 113  TYR A CA  1 
ATOM   859   C  C   . TYR A 1 113 ? 195.377 166.451 134.526 1.00 92.01  ? 113  TYR A C   1 
ATOM   860   O  O   . TYR A 1 113 ? 194.518 167.180 134.017 1.00 92.01  ? 113  TYR A O   1 
ATOM   861   C  CB  . TYR A 1 113 ? 193.567 165.017 135.517 1.00 92.01  ? 113  TYR A CB  1 
ATOM   862   C  CG  . TYR A 1 113 ? 193.095 163.625 135.872 1.00 92.01  ? 113  TYR A CG  1 
ATOM   863   C  CD1 . TYR A 1 113 ? 192.963 162.646 134.896 1.00 92.01  ? 113  TYR A CD1 1 
ATOM   864   C  CD2 . TYR A 1 113 ? 192.792 163.284 137.184 1.00 92.01  ? 113  TYR A CD2 1 
ATOM   865   C  CE1 . TYR A 1 113 ? 192.536 161.372 135.214 1.00 92.01  ? 113  TYR A CE1 1 
ATOM   866   C  CE2 . TYR A 1 113 ? 192.365 162.011 137.511 1.00 92.01  ? 113  TYR A CE2 1 
ATOM   867   C  CZ  . TYR A 1 113 ? 192.239 161.059 136.522 1.00 92.01  ? 113  TYR A CZ  1 
ATOM   868   O  OH  . TYR A 1 113 ? 191.814 159.790 136.841 1.00 92.01  ? 113  TYR A OH  1 
ATOM   869   N  N   . ALA A 1 114 ? 196.644 166.841 134.674 1.00 95.93  ? 114  ALA A N   1 
ATOM   870   C  CA  . ALA A 1 114 ? 197.118 168.089 134.092 1.00 95.93  ? 114  ALA A CA  1 
ATOM   871   C  C   . ALA A 1 114 ? 197.441 167.955 132.611 1.00 95.93  ? 114  ALA A C   1 
ATOM   872   O  O   . ALA A 1 114 ? 197.733 168.964 131.961 1.00 95.93  ? 114  ALA A O   1 
ATOM   873   C  CB  . ALA A 1 114 ? 198.352 168.588 134.845 1.00 95.93  ? 114  ALA A CB  1 
ATOM   874   N  N   . THR A 1 115 ? 197.397 166.739 132.066 1.00 106.73 ? 115  THR A N   1 
ATOM   875   C  CA  . THR A 1 115 ? 197.649 166.526 130.647 1.00 106.73 ? 115  THR A CA  1 
ATOM   876   C  C   . THR A 1 115 ? 196.415 166.881 129.829 1.00 106.73 ? 115  THR A C   1 
ATOM   877   O  O   . THR A 1 115 ? 195.847 166.021 129.148 1.00 106.73 ? 115  THR A O   1 
ATOM   878   C  CB  . THR A 1 115 ? 198.057 165.075 130.381 1.00 106.73 ? 115  THR A CB  1 
ATOM   879   O  OG1 . THR A 1 115 ? 196.914 164.222 130.524 1.00 106.73 ? 115  THR A OG1 1 
ATOM   880   C  CG2 . THR A 1 115 ? 199.136 164.636 131.359 1.00 106.73 ? 115  THR A CG2 1 
ATOM   881   N  N   . GLU A 1 116 ? 195.988 168.141 129.907 1.00 108.54 ? 116  GLU A N   1 
ATOM   882   C  CA  . GLU A 1 116 ? 194.821 168.674 129.207 1.00 108.54 ? 116  GLU A CA  1 
ATOM   883   C  C   . GLU A 1 116 ? 193.520 167.993 129.617 1.00 108.54 ? 116  GLU A C   1 
ATOM   884   O  O   . GLU A 1 116 ? 192.478 168.235 128.996 1.00 108.54 ? 116  GLU A O   1 
ATOM   885   C  CB  . GLU A 1 116 ? 194.993 168.590 127.684 1.00 108.54 ? 116  GLU A CB  1 
ATOM   886   C  CG  . GLU A 1 116 ? 196.112 169.459 127.134 1.00 108.54 ? 116  GLU A CG  1 
ATOM   887   C  CD  . GLU A 1 116 ? 196.260 169.334 125.631 1.00 108.54 ? 116  GLU A CD  1 
ATOM   888   O  OE1 . GLU A 1 116 ? 195.562 168.490 125.031 1.00 108.54 ? 116  GLU A OE1 1 
ATOM   889   O  OE2 . GLU A 1 116 ? 197.074 170.081 125.048 1.00 108.54 ? 116  GLU A OE2 1 
ATOM   890   N  N   . ASP A 1 117 ? 193.549 167.148 130.646 1.00 103.35 ? 117  ASP A N   1 
ATOM   891   C  CA  . ASP A 1 117 ? 192.353 166.444 131.110 1.00 103.35 ? 117  ASP A CA  1 
ATOM   892   C  C   . ASP A 1 117 ? 191.745 167.158 132.318 1.00 103.35 ? 117  ASP A C   1 
ATOM   893   O  O   . ASP A 1 117 ? 191.686 166.634 133.429 1.00 103.35 ? 117  ASP A O   1 
ATOM   894   C  CB  . ASP A 1 117 ? 192.687 164.993 131.433 1.00 103.35 ? 117  ASP A CB  1 
ATOM   895   C  CG  . ASP A 1 117 ? 191.453 164.117 131.513 1.00 103.35 ? 117  ASP A CG  1 
ATOM   896   O  OD1 . ASP A 1 117 ? 190.341 164.626 131.256 1.00 103.35 ? 117  ASP A OD1 1 
ATOM   897   O  OD2 . ASP A 1 117 ? 191.595 162.919 131.836 1.00 103.35 ? 117  ASP A OD2 1 
ATOM   898   N  N   . LEU A 1 118 ? 191.285 168.379 132.078 1.00 99.59  ? 118  LEU A N   1 
ATOM   899   C  CA  . LEU A 1 118 ? 190.649 169.164 133.126 1.00 99.59  ? 118  LEU A CA  1 
ATOM   900   C  C   . LEU A 1 118 ? 189.254 168.602 133.395 1.00 99.59  ? 118  LEU A C   1 
ATOM   901   O  O   . LEU A 1 118 ? 188.783 167.680 132.722 1.00 99.59  ? 118  LEU A O   1 
ATOM   902   C  CB  . LEU A 1 118 ? 190.619 170.640 132.742 1.00 99.59  ? 118  LEU A CB  1 
ATOM   903   C  CG  . LEU A 1 118 ? 191.986 171.323 132.659 1.00 99.59  ? 118  LEU A CG  1 
ATOM   904   C  CD1 . LEU A 1 118 ? 191.837 172.835 132.725 1.00 99.59  ? 118  LEU A CD1 1 
ATOM   905   C  CD2 . LEU A 1 118 ? 192.905 170.824 133.766 1.00 99.59  ? 118  LEU A CD2 1 
ATOM   906   N  N   . PHE A 1 119 ? 188.598 169.137 134.429 1.00 94.48  ? 119  PHE A N   1 
ATOM   907   C  CA  . PHE A 1 119 ? 187.256 168.737 134.848 1.00 94.48  ? 119  PHE A CA  1 
ATOM   908   C  C   . PHE A 1 119 ? 187.291 167.329 135.440 1.00 94.48  ? 119  PHE A C   1 
ATOM   909   O  O   . PHE A 1 119 ? 186.278 166.826 135.935 1.00 94.48  ? 119  PHE A O   1 
ATOM   910   C  CB  . PHE A 1 119 ? 186.269 168.844 133.675 1.00 94.48  ? 119  PHE A CB  1 
ATOM   911   C  CG  . PHE A 1 119 ? 184.883 168.358 133.988 1.00 94.48  ? 119  PHE A CG  1 
ATOM   912   C  CD1 . PHE A 1 119 ? 184.092 169.023 134.909 1.00 94.48  ? 119  PHE A CD1 1 
ATOM   913   C  CD2 . PHE A 1 119 ? 184.371 167.238 133.357 1.00 94.48  ? 119  PHE A CD2 1 
ATOM   914   C  CE1 . PHE A 1 119 ? 182.815 168.578 135.195 1.00 94.48  ? 119  PHE A CE1 1 
ATOM   915   C  CE2 . PHE A 1 119 ? 183.096 166.789 133.639 1.00 94.48  ? 119  PHE A CE2 1 
ATOM   916   C  CZ  . PHE A 1 119 ? 182.317 167.460 134.558 1.00 94.48  ? 119  PHE A CZ  1 
ATOM   917   N  N   . ALA A 1 120 ? 188.464 166.694 135.417 1.00 93.99  ? 120  ALA A N   1 
ATOM   918   C  CA  . ALA A 1 120 ? 188.653 165.452 136.158 1.00 93.99  ? 120  ALA A CA  1 
ATOM   919   C  C   . ALA A 1 120 ? 189.216 165.741 137.544 1.00 93.99  ? 120  ALA A C   1 
ATOM   920   O  O   . ALA A 1 120 ? 188.591 165.426 138.566 1.00 93.99  ? 120  ALA A O   1 
ATOM   921   C  CB  . ALA A 1 120 ? 189.577 164.513 135.382 1.00 93.99  ? 120  ALA A CB  1 
ATOM   922   N  N   . ALA A 1 121 ? 190.398 166.361 137.591 1.00 86.12  ? 121  ALA A N   1 
ATOM   923   C  CA  . ALA A 1 121 ? 190.947 166.815 138.863 1.00 86.12  ? 121  ALA A CA  1 
ATOM   924   C  C   . ALA A 1 121 ? 190.024 167.829 139.520 1.00 86.12  ? 121  ALA A C   1 
ATOM   925   O  O   . ALA A 1 121 ? 189.952 167.907 140.751 1.00 86.12  ? 121  ALA A O   1 
ATOM   926   C  CB  . ALA A 1 121 ? 192.338 167.412 138.654 1.00 86.12  ? 121  ALA A CB  1 
ATOM   927   N  N   . GLY A 1 122 ? 189.307 168.613 138.713 1.00 84.11  ? 122  GLY A N   1 
ATOM   928   C  CA  . GLY A 1 122 ? 188.343 169.544 139.274 1.00 84.11  ? 122  GLY A CA  1 
ATOM   929   C  C   . GLY A 1 122 ? 187.240 168.840 140.040 1.00 84.11  ? 122  GLY A C   1 
ATOM   930   O  O   . GLY A 1 122 ? 186.893 169.234 141.154 1.00 84.11  ? 122  GLY A O   1 
ATOM   931   N  N   . VAL A 1 123 ? 186.681 167.778 139.456 1.00 85.20  ? 123  VAL A N   1 
ATOM   932   C  CA  . VAL A 1 123 ? 185.632 167.026 140.141 1.00 85.20  ? 123  VAL A CA  1 
ATOM   933   C  C   . VAL A 1 123 ? 186.201 166.293 141.351 1.00 85.20  ? 123  VAL A C   1 
ATOM   934   O  O   . VAL A 1 123 ? 185.531 166.156 142.382 1.00 85.20  ? 123  VAL A O   1 
ATOM   935   C  CB  . VAL A 1 123 ? 184.929 166.066 139.161 1.00 85.20  ? 123  VAL A CB  1 
ATOM   936   C  CG1 . VAL A 1 123 ? 184.055 165.074 139.912 1.00 85.20  ? 123  VAL A CG1 1 
ATOM   937   C  CG2 . VAL A 1 123 ? 184.084 166.854 138.177 1.00 85.20  ? 123  VAL A CG2 1 
ATOM   938   N  N   . ILE A 1 124 ? 187.443 165.809 141.250 1.00 79.89  ? 124  ILE A N   1 
ATOM   939   C  CA  . ILE A 1 124 ? 188.074 165.163 142.403 1.00 79.89  ? 124  ILE A CA  1 
ATOM   940   C  C   . ILE A 1 124 ? 188.193 166.149 143.560 1.00 79.89  ? 124  ILE A C   1 
ATOM   941   O  O   . ILE A 1 124 ? 187.850 165.838 144.708 1.00 79.89  ? 124  ILE A O   1 
ATOM   942   C  CB  . ILE A 1 124 ? 189.445 164.582 142.015 1.00 79.89  ? 124  ILE A CB  1 
ATOM   943   C  CG1 . ILE A 1 124 ? 189.273 163.328 141.158 1.00 79.89  ? 124  ILE A CG1 1 
ATOM   944   C  CG2 . ILE A 1 124 ? 190.264 164.267 143.258 1.00 79.89  ? 124  ILE A CG2 1 
ATOM   945   C  CD1 . ILE A 1 124 ? 190.575 162.776 140.626 1.00 79.89  ? 124  ILE A CD1 1 
ATOM   946   N  N   . ALA A 1 125 ? 188.673 167.360 143.267 1.00 79.19  ? 125  ALA A N   1 
ATOM   947   C  CA  . ALA A 1 125 ? 188.788 168.386 144.297 1.00 79.19  ? 125  ALA A CA  1 
ATOM   948   C  C   . ALA A 1 125 ? 187.418 168.798 144.817 1.00 79.19  ? 125  ALA A C   1 
ATOM   949   O  O   . ALA A 1 125 ? 187.268 169.122 145.999 1.00 79.19  ? 125  ALA A O   1 
ATOM   950   C  CB  . ALA A 1 125 ? 189.542 169.598 143.750 1.00 79.19  ? 125  ALA A CB  1 
ATOM   951   N  N   . LEU A 1 126 ? 186.406 168.799 143.947 1.00 79.18  ? 126  LEU A N   1 
ATOM   952   C  CA  . LEU A 1 126 ? 185.049 169.105 144.385 1.00 79.18  ? 126  LEU A CA  1 
ATOM   953   C  C   . LEU A 1 126 ? 184.548 168.066 145.380 1.00 79.18  ? 126  LEU A C   1 
ATOM   954   O  O   . LEU A 1 126 ? 183.928 168.406 146.392 1.00 79.18  ? 126  LEU A O   1 
ATOM   955   C  CB  . LEU A 1 126 ? 184.117 169.191 143.176 1.00 79.18  ? 126  LEU A CB  1 
ATOM   956   C  CG  . LEU A 1 126 ? 182.662 169.568 143.461 1.00 79.18  ? 126  LEU A CG  1 
ATOM   957   C  CD1 . LEU A 1 126 ? 182.572 170.961 144.065 1.00 79.18  ? 126  LEU A CD1 1 
ATOM   958   C  CD2 . LEU A 1 126 ? 181.821 169.473 142.197 1.00 79.18  ? 126  LEU A CD2 1 
ATOM   959   N  N   . MET A 1 127 ? 184.806 166.787 145.104 1.00 77.98  ? 127  MET A N   1 
ATOM   960   C  CA  . MET A 1 127 ? 184.406 165.729 146.028 1.00 77.98  ? 127  MET A CA  1 
ATOM   961   C  C   . MET A 1 127 ? 185.170 165.834 147.343 1.00 77.98  ? 127  MET A C   1 
ATOM   962   O  O   . MET A 1 127 ? 184.606 165.623 148.426 1.00 77.98  ? 127  MET A O   1 
ATOM   963   C  CB  . MET A 1 127 ? 184.622 164.360 145.382 1.00 77.98  ? 127  MET A CB  1 
ATOM   964   C  CG  . MET A 1 127 ? 183.528 163.966 144.405 1.00 77.98  ? 127  MET A CG  1 
ATOM   965   S  SD  . MET A 1 127 ? 182.106 163.208 145.212 1.00 77.98  ? 127  MET A SD  1 
ATOM   966   C  CE  . MET A 1 127 ? 180.805 163.613 144.049 1.00 77.98  ? 127  MET A CE  1 
ATOM   967   N  N   . VAL A 1 128 ? 186.462 166.152 147.264 1.00 76.07  ? 128  VAL A N   1 
ATOM   968   C  CA  . VAL A 1 128 ? 187.292 166.362 148.445 1.00 76.07  ? 128  VAL A CA  1 
ATOM   969   C  C   . VAL A 1 128 ? 186.695 167.477 149.292 1.00 76.07  ? 128  VAL A C   1 
ATOM   970   O  O   . VAL A 1 128 ? 186.556 167.344 150.514 1.00 76.07  ? 128  VAL A O   1 
ATOM   971   C  CB  . VAL A 1 128 ? 188.743 166.687 148.045 1.00 76.07  ? 128  VAL A CB  1 
ATOM   972   C  CG1 . VAL A 1 128 ? 189.523 167.175 149.242 1.00 76.07  ? 128  VAL A CG1 1 
ATOM   973   C  CG2 . VAL A 1 128 ? 189.411 165.462 147.450 1.00 76.07  ? 128  VAL A CG2 1 
ATOM   974   N  N   . ALA A 1 129 ? 186.325 168.580 148.639 1.00 74.10  ? 129  ALA A N   1 
ATOM   975   C  CA  . ALA A 1 129 ? 185.736 169.708 149.348 1.00 74.10  ? 129  ALA A CA  1 
ATOM   976   C  C   . ALA A 1 129 ? 184.386 169.342 149.949 1.00 74.10  ? 129  ALA A C   1 
ATOM   977   O  O   . ALA A 1 129 ? 184.060 169.770 151.058 1.00 74.10  ? 129  ALA A O   1 
ATOM   978   C  CB  . ALA A 1 129 ? 185.596 170.903 148.405 1.00 74.10  ? 129  ALA A CB  1 
ATOM   979   N  N   . ILE A 1 130 ? 183.581 168.561 149.230 1.00 73.46  ? 130  ILE A N   1 
ATOM   980   C  CA  . ILE A 1 130 ? 182.280 168.172 149.764 1.00 73.46  ? 130  ILE A CA  1 
ATOM   981   C  C   . ILE A 1 130 ? 182.453 167.328 151.020 1.00 73.46  ? 130  ILE A C   1 
ATOM   982   O  O   . ILE A 1 130 ? 181.761 167.536 152.024 1.00 73.46  ? 130  ILE A O   1 
ATOM   983   C  CB  . ILE A 1 130 ? 181.454 167.443 148.689 1.00 73.46  ? 130  ILE A CB  1 
ATOM   984   C  CG1 . ILE A 1 130 ? 181.001 168.429 147.610 1.00 73.46  ? 130  ILE A CG1 1 
ATOM   985   C  CG2 . ILE A 1 130 ? 180.246 166.770 149.312 1.00 73.46  ? 130  ILE A CG2 1 
ATOM   986   C  CD1 . ILE A 1 130 ? 180.161 167.797 146.521 1.00 73.46  ? 130  ILE A CD1 1 
ATOM   987   N  N   . SER A 1 131 ? 183.389 166.376 150.994 1.00 72.01  ? 131  SER A N   1 
ATOM   988   C  CA  . SER A 1 131 ? 183.666 165.587 152.191 1.00 72.01  ? 131  SER A CA  1 
ATOM   989   C  C   . SER A 1 131 ? 184.176 166.467 153.327 1.00 72.01  ? 131  SER A C   1 
ATOM   990   O  O   . SER A 1 131 ? 183.788 166.286 154.491 1.00 72.01  ? 131  SER A O   1 
ATOM   991   C  CB  . SER A 1 131 ? 184.674 164.483 151.871 1.00 72.01  ? 131  SER A CB  1 
ATOM   992   O  OG  . SER A 1 131 ? 184.970 163.711 153.022 1.00 72.01  ? 131  SER A OG  1 
ATOM   993   N  N   . THR A 1 132 ? 185.049 167.428 153.008 1.00 73.00  ? 132  THR A N   1 
ATOM   994   C  CA  . THR A 1 132 ? 185.590 168.312 154.036 1.00 73.00  ? 132  THR A CA  1 
ATOM   995   C  C   . THR A 1 132 ? 184.492 169.147 154.684 1.00 73.00  ? 132  THR A C   1 
ATOM   996   O  O   . THR A 1 132 ? 184.447 169.277 155.912 1.00 73.00  ? 132  THR A O   1 
ATOM   997   C  CB  . THR A 1 132 ? 186.668 169.216 153.437 1.00 73.00  ? 132  THR A CB  1 
ATOM   998   O  OG1 . THR A 1 132 ? 187.765 168.415 152.980 1.00 73.00  ? 132  THR A OG1 1 
ATOM   999   C  CG2 . THR A 1 132 ? 187.173 170.205 154.474 1.00 73.00  ? 132  THR A CG2 1 
ATOM   1000  N  N   . LEU A 1 133 ? 183.593 169.716 153.877 1.00 71.96  ? 133  LEU A N   1 
ATOM   1001  C  CA  . LEU A 1 133 ? 182.485 170.491 154.431 1.00 71.96  ? 133  LEU A CA  1 
ATOM   1002  C  C   . LEU A 1 133 ? 181.508 169.615 155.205 1.00 71.96  ? 133  LEU A C   1 
ATOM   1003  O  O   . LEU A 1 133 ? 180.948 170.056 156.211 1.00 71.96  ? 133  LEU A O   1 
ATOM   1004  C  CB  . LEU A 1 133 ? 181.761 171.277 153.335 1.00 71.96  ? 133  LEU A CB  1 
ATOM   1005  C  CG  . LEU A 1 133 ? 182.356 172.616 152.874 1.00 71.96  ? 133  LEU A CG  1 
ATOM   1006  C  CD1 . LEU A 1 133 ? 183.617 172.499 152.044 1.00 71.96  ? 133  LEU A CD1 1 
ATOM   1007  C  CD2 . LEU A 1 133 ? 181.296 173.403 152.109 1.00 71.96  ? 133  LEU A CD2 1 
ATOM   1008  N  N   . LEU A 1 134 ? 181.287 168.375 154.763 1.00 67.36  ? 134  LEU A N   1 
ATOM   1009  C  CA  . LEU A 1 134 ? 180.450 167.465 155.543 1.00 67.36  ? 134  LEU A CA  1 
ATOM   1010  C  C   . LEU A 1 134 ? 181.038 167.238 156.931 1.00 67.36  ? 134  LEU A C   1 
ATOM   1011  O  O   . LEU A 1 134 ? 180.347 167.384 157.952 1.00 67.36  ? 134  LEU A O   1 
ATOM   1012  C  CB  . LEU A 1 134 ? 180.292 166.135 154.804 1.00 67.36  ? 134  LEU A CB  1 
ATOM   1013  C  CG  . LEU A 1 134 ? 179.601 165.010 155.579 1.00 67.36  ? 134  LEU A CG  1 
ATOM   1014  C  CD1 . LEU A 1 134 ? 178.148 165.353 155.852 1.00 67.36  ? 134  LEU A CD1 1 
ATOM   1015  C  CD2 . LEU A 1 134 ? 179.716 163.686 154.835 1.00 67.36  ? 134  LEU A CD2 1 
ATOM   1016  N  N   . ASN A 1 135 ? 182.328 166.896 156.982 1.00 65.74  ? 135  ASN A N   1 
ATOM   1017  C  CA  . ASN A 1 135 ? 182.989 166.664 158.261 1.00 65.74  ? 135  ASN A CA  1 
ATOM   1018  C  C   . ASN A 1 135 ? 182.965 167.921 159.121 1.00 65.74  ? 135  ASN A C   1 
ATOM   1019  O  O   . ASN A 1 135 ? 182.702 167.860 160.329 1.00 65.74  ? 135  ASN A O   1 
ATOM   1020  C  CB  . ASN A 1 135 ? 184.427 166.199 158.026 1.00 65.74  ? 135  ASN A CB  1 
ATOM   1021  C  CG  . ASN A 1 135 ? 184.520 164.716 157.734 1.00 65.74  ? 135  ASN A CG  1 
ATOM   1022  O  OD1 . ASN A 1 135 ? 183.524 164.074 157.401 1.00 65.74  ? 135  ASN A OD1 1 
ATOM   1023  N  ND2 . ASN A 1 135 ? 185.720 164.161 157.859 1.00 65.74  ? 135  ASN A ND2 1 
ATOM   1024  N  N   . PHE A 1 136 ? 183.233 169.077 158.509 1.00 68.80  ? 136  PHE A N   1 
ATOM   1025  C  CA  . PHE A 1 136 ? 183.270 170.326 159.258 1.00 68.80  ? 136  PHE A CA  1 
ATOM   1026  C  C   . PHE A 1 136 ? 181.899 170.684 159.812 1.00 68.80  ? 136  PHE A C   1 
ATOM   1027  O  O   . PHE A 1 136 ? 181.791 171.163 160.943 1.00 68.80  ? 136  PHE A O   1 
ATOM   1028  C  CB  . PHE A 1 136 ? 183.802 171.454 158.376 1.00 68.80  ? 136  PHE A CB  1 
ATOM   1029  C  CG  . PHE A 1 136 ? 183.427 172.827 158.855 1.00 68.80  ? 136  PHE A CG  1 
ATOM   1030  C  CD1 . PHE A 1 136 ? 184.138 173.435 159.874 1.00 68.80  ? 136  PHE A CD1 1 
ATOM   1031  C  CD2 . PHE A 1 136 ? 182.371 173.513 158.279 1.00 68.80  ? 136  PHE A CD2 1 
ATOM   1032  C  CE1 . PHE A 1 136 ? 183.799 174.697 160.316 1.00 68.80  ? 136  PHE A CE1 1 
ATOM   1033  C  CE2 . PHE A 1 136 ? 182.027 174.775 158.717 1.00 68.80  ? 136  PHE A CE2 1 
ATOM   1034  C  CZ  . PHE A 1 136 ? 182.743 175.369 159.736 1.00 68.80  ? 136  PHE A CZ  1 
ATOM   1035  N  N   . ILE A 1 137 ? 180.841 170.479 159.026 1.00 66.64  ? 137  ILE A N   1 
ATOM   1036  C  CA  . ILE A 1 137 ? 179.493 170.772 159.503 1.00 66.64  ? 137  ILE A CA  1 
ATOM   1037  C  C   . ILE A 1 137 ? 179.146 169.874 160.682 1.00 66.64  ? 137  ILE A C   1 
ATOM   1038  O  O   . ILE A 1 137 ? 178.624 170.337 161.706 1.00 66.64  ? 137  ILE A O   1 
ATOM   1039  C  CB  . ILE A 1 137 ? 178.473 170.625 158.360 1.00 66.64  ? 137  ILE A CB  1 
ATOM   1040  C  CG1 . ILE A 1 137 ? 178.550 171.827 157.417 1.00 66.64  ? 137  ILE A CG1 1 
ATOM   1041  C  CG2 . ILE A 1 137 ? 177.065 170.464 158.912 1.00 66.64  ? 137  ILE A CG2 1 
ATOM   1042  C  CD1 . ILE A 1 137 ? 177.673 171.694 156.193 1.00 66.64  ? 137  ILE A CD1 1 
ATOM   1043  N  N   . GLN A 1 138 ? 179.441 168.576 160.561 1.00 60.47  ? 138  GLN A N   1 
ATOM   1044  C  CA  . GLN A 1 138 ? 179.181 167.663 161.671 1.00 60.47  ? 138  GLN A CA  1 
ATOM   1045  C  C   . GLN A 1 138 ? 179.915 168.109 162.931 1.00 60.47  ? 138  GLN A C   1 
ATOM   1046  O  O   . GLN A 1 138 ? 179.308 168.257 164.004 1.00 60.47  ? 138  GLN A O   1 
ATOM   1047  C  CB  . GLN A 1 138 ? 179.587 166.240 161.288 1.00 60.47  ? 138  GLN A CB  1 
ATOM   1048  C  CG  . GLN A 1 138 ? 178.624 165.539 160.343 1.00 60.47  ? 138  GLN A CG  1 
ATOM   1049  C  CD  . GLN A 1 138 ? 177.407 164.977 161.055 1.00 60.47  ? 138  GLN A CD  1 
ATOM   1050  O  OE1 . GLN A 1 138 ? 176.720 165.683 161.795 1.00 60.47  ? 138  GLN A OE1 1 
ATOM   1051  N  NE2 . GLN A 1 138 ? 177.138 163.696 160.839 1.00 60.47  ? 138  GLN A NE2 1 
ATOM   1052  N  N   . GLU A 1 139 ? 181.224 168.351 162.813 1.00 59.84  ? 139  GLU A N   1 
ATOM   1053  C  CA  . GLU A 1 139 ? 182.014 168.723 163.981 1.00 59.84  ? 139  GLU A CA  1 
ATOM   1054  C  C   . GLU A 1 139 ? 181.551 170.048 164.570 1.00 59.84  ? 139  GLU A C   1 
ATOM   1055  O  O   . GLU A 1 139 ? 181.445 170.181 165.792 1.00 59.84  ? 139  GLU A O   1 
ATOM   1056  C  CB  . GLU A 1 139 ? 183.499 168.786 163.623 1.00 59.84  ? 139  GLU A CB  1 
ATOM   1057  C  CG  . GLU A 1 139 ? 184.071 167.478 163.109 1.00 59.84  ? 139  GLU A CG  1 
ATOM   1058  C  CD  . GLU A 1 139 ? 185.570 167.543 162.896 1.00 59.84  ? 139  GLU A CD  1 
ATOM   1059  O  OE1 . GLU A 1 139 ? 186.230 168.364 163.565 1.00 59.84  ? 139  GLU A OE1 1 
ATOM   1060  O  OE2 . GLU A 1 139 ? 186.089 166.772 162.063 1.00 59.84  ? 139  GLU A OE2 1 
ATOM   1061  N  N   . ALA A 1 140 ? 181.269 171.040 163.723 1.00 56.62  ? 140  ALA A N   1 
ATOM   1062  C  CA  . ALA A 1 140 ? 180.869 172.349 164.222 1.00 56.62  ? 140  ALA A CA  1 
ATOM   1063  C  C   . ALA A 1 140 ? 179.532 172.285 164.945 1.00 56.62  ? 140  ALA A C   1 
ATOM   1064  O  O   . ALA A 1 140 ? 179.387 172.848 166.035 1.00 56.62  ? 140  ALA A O   1 
ATOM   1065  C  CB  . ALA A 1 140 ? 180.810 173.354 163.073 1.00 56.62  ? 140  ALA A CB  1 
ATOM   1066  N  N   . ARG A 1 141 ? 178.545 171.598 164.362 1.00 58.75  ? 141  ARG A N   1 
ATOM   1067  C  CA  . ARG A 1 141 ? 177.252 171.475 165.026 1.00 58.75  ? 141  ARG A CA  1 
ATOM   1068  C  C   . ARG A 1 141 ? 177.385 170.754 166.360 1.00 58.75  ? 141  ARG A C   1 
ATOM   1069  O  O   . ARG A 1 141 ? 176.835 171.201 167.377 1.00 58.75  ? 141  ARG A O   1 
ATOM   1070  C  CB  . ARG A 1 141 ? 176.263 170.743 164.120 1.00 58.75  ? 141  ARG A CB  1 
ATOM   1071  C  CG  . ARG A 1 141 ? 175.267 171.650 163.422 1.00 58.75  ? 141  ARG A CG  1 
ATOM   1072  C  CD  . ARG A 1 141 ? 174.256 170.852 162.613 1.00 58.75  ? 141  ARG A CD  1 
ATOM   1073  N  NE  . ARG A 1 141 ? 173.380 170.047 163.456 1.00 58.75  ? 141  ARG A NE  1 
ATOM   1074  C  CZ  . ARG A 1 141 ? 173.511 168.740 163.642 1.00 58.75  ? 141  ARG A CZ  1 
ATOM   1075  N  NH1 . ARG A 1 141 ? 174.481 168.053 163.062 1.00 58.75  ? 141  ARG A NH1 1 
ATOM   1076  N  NH2 . ARG A 1 141 ? 172.645 168.107 164.428 1.00 58.75  ? 141  ARG A NH2 1 
ATOM   1077  N  N   . SER A 1 142 ? 178.126 169.644 166.382 1.00 50.19  ? 142  SER A N   1 
ATOM   1078  C  CA  . SER A 1 142 ? 178.245 168.883 167.619 1.00 50.19  ? 142  SER A CA  1 
ATOM   1079  C  C   . SER A 1 142 ? 179.011 169.660 168.686 1.00 50.19  ? 142  SER A C   1 
ATOM   1080  O  O   . SER A 1 142 ? 178.638 169.634 169.864 1.00 50.19  ? 142  SER A O   1 
ATOM   1081  C  CB  . SER A 1 142 ? 178.908 167.541 167.336 1.00 50.19  ? 142  SER A CB  1 
ATOM   1082  O  OG  . SER A 1 142 ? 178.236 166.852 166.297 1.00 50.19  ? 142  SER A OG  1 
ATOM   1083  N  N   . THR A 1 143 ? 180.084 170.358 168.299 1.00 48.08  ? 143  THR A N   1 
ATOM   1084  C  CA  . THR A 1 143 ? 180.834 171.155 169.264 1.00 48.08  ? 143  THR A CA  1 
ATOM   1085  C  C   . THR A 1 143 ? 180.004 172.316 169.790 1.00 48.08  ? 143  THR A C   1 
ATOM   1086  O  O   . THR A 1 143 ? 180.091 172.655 170.974 1.00 48.08  ? 143  THR A O   1 
ATOM   1087  C  CB  . THR A 1 143 ? 182.132 171.671 168.644 1.00 48.08  ? 143  THR A CB  1 
ATOM   1088  O  OG1 . THR A 1 143 ? 181.845 172.342 167.411 1.00 48.08  ? 143  THR A OG1 1 
ATOM   1089  C  CG2 . THR A 1 143 ? 183.107 170.530 168.399 1.00 48.08  ? 143  THR A CG2 1 
ATOM   1090  N  N   . LYS A 1 144 ? 179.208 172.953 168.927 1.00 48.19  ? 144  LYS A N   1 
ATOM   1091  C  CA  . LYS A 1 144 ? 178.330 174.017 169.397 1.00 48.19  ? 144  LYS A CA  1 
ATOM   1092  C  C   . LYS A 1 144 ? 177.321 173.484 170.404 1.00 48.19  ? 144  LYS A C   1 
ATOM   1093  O  O   . LYS A 1 144 ? 177.076 174.112 171.443 1.00 48.19  ? 144  LYS A O   1 
ATOM   1094  C  CB  . LYS A 1 144 ? 177.618 174.671 168.213 1.00 48.19  ? 144  LYS A CB  1 
ATOM   1095  C  CG  . LYS A 1 144 ? 176.794 175.893 168.581 1.00 48.19  ? 144  LYS A CG  1 
ATOM   1096  C  CD  . LYS A 1 144 ? 176.302 176.619 167.338 1.00 48.19  ? 144  LYS A CD  1 
ATOM   1097  C  CE  . LYS A 1 144 ? 175.462 177.831 167.703 1.00 48.19  ? 144  LYS A CE  1 
ATOM   1098  N  NZ  . LYS A 1 144 ? 174.151 177.437 168.290 1.00 48.19  ? 144  LYS A NZ  1 
ATOM   1099  N  N   . ALA A 1 145 ? 176.737 172.315 170.124 1.00 45.56  ? 145  ALA A N   1 
ATOM   1100  C  CA  . ALA A 1 145 ? 175.800 171.720 171.072 1.00 45.56  ? 145  ALA A CA  1 
ATOM   1101  C  C   . ALA A 1 145 ? 176.485 171.391 172.394 1.00 45.56  ? 145  ALA A C   1 
ATOM   1102  O  O   . ALA A 1 145 ? 175.934 171.654 173.470 1.00 45.56  ? 145  ALA A O   1 
ATOM   1103  C  CB  . ALA A 1 145 ? 175.164 170.468 170.470 1.00 45.56  ? 145  ALA A CB  1 
ATOM   1104  N  N   . ALA A 1 146 ? 177.692 170.823 172.333 1.00 42.38  ? 146  ALA A N   1 
ATOM   1105  C  CA  . ALA A 1 146 ? 178.407 170.464 173.554 1.00 42.38  ? 146  ALA A CA  1 
ATOM   1106  C  C   . ALA A 1 146 ? 178.772 171.698 174.370 1.00 42.38  ? 146  ALA A C   1 
ATOM   1107  O  O   . ALA A 1 146 ? 178.667 171.690 175.602 1.00 42.38  ? 146  ALA A O   1 
ATOM   1108  C  CB  . ALA A 1 146 ? 179.659 169.658 173.210 1.00 42.38  ? 146  ALA A CB  1 
ATOM   1109  N  N   . ASP A 1 147 ? 179.212 172.766 173.702 1.00 43.07  ? 147  ASP A N   1 
ATOM   1110  C  CA  . ASP A 1 147 ? 179.553 173.995 174.409 1.00 43.07  ? 147  ASP A CA  1 
ATOM   1111  C  C   . ASP A 1 147 ? 178.318 174.631 175.033 1.00 43.07  ? 147  ASP A C   1 
ATOM   1112  O  O   . ASP A 1 147 ? 178.381 175.151 176.153 1.00 43.07  ? 147  ASP A O   1 
ATOM   1113  C  CB  . ASP A 1 147 ? 180.243 174.971 173.458 1.00 43.07  ? 147  ASP A CB  1 
ATOM   1114  C  CG  . ASP A 1 147 ? 181.694 174.611 173.210 1.00 43.07  ? 147  ASP A CG  1 
ATOM   1115  O  OD1 . ASP A 1 147 ? 182.249 173.809 173.990 1.00 43.07  ? 147  ASP A OD1 1 
ATOM   1116  O  OD2 . ASP A 1 147 ? 182.279 175.128 172.235 1.00 43.07  ? 147  ASP A OD2 1 
ATOM   1117  N  N   . ALA A 1 148 ? 177.185 174.597 174.329 1.00 42.60  ? 148  ALA A N   1 
ATOM   1118  C  CA  . ALA A 1 148 ? 175.945 175.088 174.919 1.00 42.60  ? 148  ALA A CA  1 
ATOM   1119  C  C   . ALA A 1 148 ? 175.562 174.275 176.148 1.00 42.60  ? 148  ALA A C   1 
ATOM   1120  O  O   . ALA A 1 148 ? 175.135 174.835 177.165 1.00 42.60  ? 148  ALA A O   1 
ATOM   1121  C  CB  . ALA A 1 148 ? 174.821 175.059 173.884 1.00 42.60  ? 148  ALA A CB  1 
ATOM   1122  N  N   . LEU A 1 149 ? 175.713 172.950 176.075 1.00 39.09  ? 149  LEU A N   1 
ATOM   1123  C  CA  . LEU A 1 149 ? 175.397 172.107 177.225 1.00 39.09  ? 149  LEU A CA  1 
ATOM   1124  C  C   . LEU A 1 149 ? 176.309 172.418 178.404 1.00 39.09  ? 149  LEU A C   1 
ATOM   1125  O  O   . LEU A 1 149 ? 175.850 172.486 179.550 1.00 39.09  ? 149  LEU A O   1 
ATOM   1126  C  CB  . LEU A 1 149 ? 175.503 170.633 176.843 1.00 39.09  ? 149  LEU A CB  1 
ATOM   1127  C  CG  . LEU A 1 149 ? 174.461 170.137 175.841 1.00 39.09  ? 149  LEU A CG  1 
ATOM   1128  C  CD1 . LEU A 1 149 ? 174.503 168.622 175.720 1.00 39.09  ? 149  LEU A CD1 1 
ATOM   1129  C  CD2 . LEU A 1 149 ? 173.071 170.625 176.218 1.00 39.09  ? 149  LEU A CD2 1 
ATOM   1130  N  N   . LYS A 1 150 ? 177.604 172.607 178.144 1.00 36.00  ? 150  LYS A N   1 
ATOM   1131  C  CA  . LYS A 1 150 ? 178.534 172.956 179.211 1.00 36.00  ? 150  LYS A CA  1 
ATOM   1132  C  C   . LYS A 1 150 ? 178.252 174.332 179.795 1.00 36.00  ? 150  LYS A C   1 
ATOM   1133  O  O   . LYS A 1 150 ? 178.493 174.547 180.987 1.00 36.00  ? 150  LYS A O   1 
ATOM   1134  C  CB  . LYS A 1 150 ? 179.973 172.894 178.700 1.00 36.00  ? 150  LYS A CB  1 
ATOM   1135  C  CG  . LYS A 1 150 ? 181.022 172.905 179.798 1.00 36.00  ? 150  LYS A CG  1 
ATOM   1136  C  CD  . LYS A 1 150 ? 182.427 172.912 179.221 1.00 36.00  ? 150  LYS A CD  1 
ATOM   1137  C  CE  . LYS A 1 150 ? 183.462 172.583 180.283 1.00 36.00  ? 150  LYS A CE  1 
ATOM   1138  N  NZ  . LYS A 1 150 ? 183.503 173.615 181.356 1.00 36.00  ? 150  LYS A NZ  1 
ATOM   1139  N  N   . ALA A 1 151 ? 177.750 175.265 178.988 1.00 42.09  ? 151  ALA A N   1 
ATOM   1140  C  CA  . ALA A 1 151 ? 177.391 176.585 179.485 1.00 42.09  ? 151  ALA A CA  1 
ATOM   1141  C  C   . ALA A 1 151 ? 176.031 176.617 180.167 1.00 42.09  ? 151  ALA A C   1 
ATOM   1142  O  O   . ALA A 1 151 ? 175.721 177.598 180.851 1.00 42.09  ? 151  ALA A O   1 
ATOM   1143  C  CB  . ALA A 1 151 ? 177.410 177.607 178.344 1.00 42.09  ? 151  ALA A CB  1 
ATOM   1144  N  N   . MET A 1 152 ? 175.209 175.579 179.986 1.00 44.45  ? 152  MET A N   1 
ATOM   1145  C  CA  . MET A 1 152 ? 173.930 175.523 180.688 1.00 44.45  ? 152  MET A CA  1 
ATOM   1146  C  C   . MET A 1 152 ? 174.129 175.465 182.197 1.00 44.45  ? 152  MET A C   1 
ATOM   1147  O  O   . MET A 1 152 ? 173.441 176.165 182.949 1.00 44.45  ? 152  MET A O   1 
ATOM   1148  C  CB  . MET A 1 152 ? 173.114 174.322 180.215 1.00 44.45  ? 152  MET A CB  1 
ATOM   1149  C  CG  . MET A 1 152 ? 172.458 174.504 178.860 1.00 44.45  ? 152  MET A CG  1 
ATOM   1150  S  SD  . MET A 1 152 ? 171.471 173.075 178.380 1.00 44.45  ? 152  MET A SD  1 
ATOM   1151  C  CE  . MET A 1 152 ? 170.238 173.064 179.679 1.00 44.45  ? 152  MET A CE  1 
ATOM   1152  N  N   . VAL A 1 153 ? 175.061 174.634 182.661 1.00 42.60  ? 153  VAL A N   1 
ATOM   1153  C  CA  . VAL A 1 153 ? 175.360 174.546 184.086 1.00 42.60  ? 153  VAL A CA  1 
ATOM   1154  C  C   . VAL A 1 153 ? 176.761 175.089 184.352 1.00 42.60  ? 153  VAL A C   1 
ATOM   1155  O  O   . VAL A 1 153 ? 177.755 174.357 184.299 1.00 42.60  ? 153  VAL A O   1 
ATOM   1156  C  CB  . VAL A 1 153 ? 175.189 173.104 184.603 1.00 42.60  ? 153  VAL A CB  1 
ATOM   1157  C  CG1 . VAL A 1 153 ? 173.716 172.744 184.652 1.00 42.60  ? 153  VAL A CG1 1 
ATOM   1158  C  CG2 . VAL A 1 153 ? 175.914 172.113 183.704 1.00 42.60  ? 153  VAL A CG2 1 
ATOM   1159  N  N   . SER A 1 154 ? 176.844 176.382 184.646 1.00 50.73  ? 154  SER A N   1 
ATOM   1160  C  CA  . SER A 1 154 ? 178.110 177.044 184.917 1.00 50.73  ? 154  SER A CA  1 
ATOM   1161  C  C   . SER A 1 154 ? 177.972 177.886 186.174 1.00 50.73  ? 154  SER A C   1 
ATOM   1162  O  O   . SER A 1 154 ? 176.896 178.421 186.456 1.00 50.73  ? 154  SER A O   1 
ATOM   1163  C  CB  . SER A 1 154 ? 178.545 177.923 183.740 1.00 50.73  ? 154  SER A CB  1 
ATOM   1164  O  OG  . SER A 1 154 ? 179.883 178.359 183.900 1.00 50.73  ? 154  SER A OG  1 
ATOM   1165  N  N   . ASN A 1 155 ? 179.062 177.990 186.931 1.00 56.78  ? 155  ASN A N   1 
ATOM   1166  C  CA  . ASN A 1 155 ? 179.049 178.785 188.150 1.00 56.78  ? 155  ASN A CA  1 
ATOM   1167  C  C   . ASN A 1 155 ? 178.739 180.239 187.825 1.00 56.78  ? 155  ASN A C   1 
ATOM   1168  O  O   . ASN A 1 155 ? 179.319 180.821 186.904 1.00 56.78  ? 155  ASN A O   1 
ATOM   1169  C  CB  . ASN A 1 155 ? 180.395 178.676 188.865 1.00 56.78  ? 155  ASN A CB  1 
ATOM   1170  C  CG  . ASN A 1 155 ? 180.528 177.394 189.658 1.00 56.78  ? 155  ASN A CG  1 
ATOM   1171  O  OD1 . ASN A 1 155 ? 179.561 176.653 189.828 1.00 56.78  ? 155  ASN A OD1 1 
ATOM   1172  N  ND2 . ASN A 1 155 ? 181.732 177.125 190.148 1.00 56.78  ? 155  ASN A ND2 1 
ATOM   1173  N  N   . THR A 1 156 ? 177.816 180.822 188.580 1.00 68.05  ? 156  THR A N   1 
ATOM   1174  C  CA  . THR A 1 156 ? 177.384 182.194 188.374 1.00 68.05  ? 156  THR A CA  1 
ATOM   1175  C  C   . THR A 1 156 ? 177.783 183.058 189.562 1.00 68.05  ? 156  THR A C   1 
ATOM   1176  O  O   . THR A 1 156 ? 178.039 182.571 190.666 1.00 68.05  ? 156  THR A O   1 
ATOM   1177  C  CB  . THR A 1 156 ? 175.868 182.267 188.155 1.00 68.05  ? 156  THR A CB  1 
ATOM   1178  O  OG1 . THR A 1 156 ? 175.191 181.975 189.384 1.00 68.05  ? 156  THR A OG1 1 
ATOM   1179  C  CG2 . THR A 1 156 ? 175.433 181.271 187.092 1.00 68.05  ? 156  THR A CG2 1 
ATOM   1180  N  N   . ALA A 1 157 ? 177.830 184.363 189.314 1.00 73.62  ? 157  ALA A N   1 
ATOM   1181  C  CA  . ALA A 1 157 ? 178.156 185.348 190.329 1.00 73.62  ? 157  ALA A CA  1 
ATOM   1182  C  C   . ALA A 1 157 ? 177.154 186.489 190.261 1.00 73.62  ? 157  ALA A C   1 
ATOM   1183  O  O   . ALA A 1 157 ? 176.581 186.776 189.205 1.00 73.62  ? 157  ALA A O   1 
ATOM   1184  C  CB  . ALA A 1 157 ? 179.582 185.889 190.156 1.00 73.62  ? 157  ALA A CB  1 
ATOM   1185  N  N   . THR A 1 158 ? 176.952 187.139 191.403 1.00 79.59  ? 158  THR A N   1 
ATOM   1186  C  CA  . THR A 1 158 ? 176.019 188.251 191.513 1.00 79.59  ? 158  THR A CA  1 
ATOM   1187  C  C   . THR A 1 158 ? 176.793 189.559 191.392 1.00 79.59  ? 158  THR A C   1 
ATOM   1188  O  O   . THR A 1 158 ? 177.696 189.828 192.191 1.00 79.59  ? 158  THR A O   1 
ATOM   1189  C  CB  . THR A 1 158 ? 175.262 188.188 192.837 1.00 79.59  ? 158  THR A CB  1 
ATOM   1190  O  OG1 . THR A 1 158 ? 174.707 186.878 193.007 1.00 79.59  ? 158  THR A OG1 1 
ATOM   1191  C  CG2 . THR A 1 158 ? 174.138 189.199 192.846 1.00 79.59  ? 158  THR A CG2 1 
ATOM   1192  N  N   . VAL A 1 159 ? 176.438 190.367 190.398 1.00 84.42  ? 159  VAL A N   1 
ATOM   1193  C  CA  . VAL A 1 159 ? 177.173 191.582 190.074 1.00 84.42  ? 159  VAL A CA  1 
ATOM   1194  C  C   . VAL A 1 159 ? 176.227 192.773 190.124 1.00 84.42  ? 159  VAL A C   1 
ATOM   1195  O  O   . VAL A 1 159 ? 175.016 192.640 189.922 1.00 84.42  ? 159  VAL A O   1 
ATOM   1196  C  CB  . VAL A 1 159 ? 177.844 191.486 188.688 1.00 84.42  ? 159  VAL A CB  1 
ATOM   1197  C  CG1 . VAL A 1 159 ? 179.013 190.523 188.731 1.00 84.42  ? 159  VAL A CG1 1 
ATOM   1198  C  CG2 . VAL A 1 159 ? 176.830 191.049 187.649 1.00 84.42  ? 159  VAL A CG2 1 
ATOM   1199  N  N   . LEU A 1 160 ? 176.794 193.946 190.405 1.00 93.93  ? 160  LEU A N   1 
ATOM   1200  C  CA  . LEU A 1 160 ? 176.027 195.185 190.411 1.00 93.93  ? 160  LEU A CA  1 
ATOM   1201  C  C   . LEU A 1 160 ? 175.499 195.513 189.020 1.00 93.93  ? 160  LEU A C   1 
ATOM   1202  O  O   . LEU A 1 160 ? 174.283 195.519 188.797 1.00 93.93  ? 160  LEU A O   1 
ATOM   1203  C  CB  . LEU A 1 160 ? 176.886 196.340 190.932 1.00 93.93  ? 160  LEU A CB  1 
ATOM   1204  C  CG  . LEU A 1 160 ? 176.771 196.663 192.422 1.00 93.93  ? 160  LEU A CG  1 
ATOM   1205  C  CD1 . LEU A 1 160 ? 177.809 197.697 192.824 1.00 93.93  ? 160  LEU A CD1 1 
ATOM   1206  C  CD2 . LEU A 1 160 ? 175.370 197.149 192.757 1.00 93.93  ? 160  LEU A CD2 1 
ATOM   1207  N  N   . ARG A 1 161 ? 176.412 195.777 188.082 1.00 101.13 ? 161  ARG A N   1 
ATOM   1208  C  CA  . ARG A 1 161 ? 176.081 196.140 186.707 1.00 101.13 ? 161  ARG A CA  1 
ATOM   1209  C  C   . ARG A 1 161 ? 175.118 197.319 186.626 1.00 101.13 ? 161  ARG A C   1 
ATOM   1210  O  O   . ARG A 1 161 ? 174.910 198.037 187.609 1.00 101.13 ? 161  ARG A O   1 
ATOM   1211  C  CB  . ARG A 1 161 ? 175.496 194.938 185.959 1.00 101.13 ? 161  ARG A CB  1 
ATOM   1212  C  CG  . ARG A 1 161 ? 176.532 193.918 185.513 1.00 101.13 ? 161  ARG A CG  1 
ATOM   1213  C  CD  . ARG A 1 161 ? 177.803 194.597 185.021 1.00 101.13 ? 161  ARG A CD  1 
ATOM   1214  N  NE  . ARG A 1 161 ? 178.923 193.670 184.907 1.00 101.13 ? 161  ARG A NE  1 
ATOM   1215  C  CZ  . ARG A 1 161 ? 179.034 192.734 183.974 1.00 101.13 ? 161  ARG A CZ  1 
ATOM   1216  N  NH1 . ARG A 1 161 ? 178.114 192.579 183.036 1.00 101.13 ? 161  ARG A NH1 1 
ATOM   1217  N  NH2 . ARG A 1 161 ? 180.098 191.937 183.978 1.00 101.13 ? 161  ARG A NH2 1 
ATOM   1218  N  N   . VAL A 1 162 ? 174.540 197.532 185.446 1.00 112.60 ? 162  VAL A N   1 
ATOM   1219  C  CA  . VAL A 1 162 ? 173.579 198.603 185.210 1.00 112.60 ? 162  VAL A CA  1 
ATOM   1220  C  C   . VAL A 1 162 ? 172.401 198.025 184.440 1.00 112.60 ? 162  VAL A C   1 
ATOM   1221  O  O   . VAL A 1 162 ? 172.584 197.294 183.461 1.00 112.60 ? 162  VAL A O   1 
ATOM   1222  C  CB  . VAL A 1 162 ? 174.217 199.782 184.444 1.00 112.60 ? 162  VAL A CB  1 
ATOM   1223  C  CG1 . VAL A 1 162 ? 173.153 200.767 183.991 1.00 112.60 ? 162  VAL A CG1 1 
ATOM   1224  C  CG2 . VAL A 1 162 ? 175.251 200.481 185.313 1.00 112.60 ? 162  VAL A CG2 1 
ATOM   1225  N  N   . ILE A 1 163 ? 171.190 198.351 184.884 1.00 119.87 ? 163  ILE A N   1 
ATOM   1226  C  CA  . ILE A 1 163 ? 169.960 197.857 184.275 1.00 119.87 ? 163  ILE A CA  1 
ATOM   1227  C  C   . ILE A 1 163 ? 169.281 199.009 183.549 1.00 119.87 ? 163  ILE A C   1 
ATOM   1228  O  O   . ILE A 1 163 ? 169.108 200.094 184.118 1.00 119.87 ? 163  ILE A O   1 
ATOM   1229  C  CB  . ILE A 1 163 ? 169.019 197.238 185.322 1.00 119.87 ? 163  ILE A CB  1 
ATOM   1230  C  CG1 . ILE A 1 163 ? 169.725 196.111 186.076 1.00 119.87 ? 163  ILE A CG1 1 
ATOM   1231  C  CG2 . ILE A 1 163 ? 167.749 196.725 184.660 1.00 119.87 ? 163  ILE A CG2 1 
ATOM   1232  C  CD1 . ILE A 1 163 ? 168.828 195.375 187.046 1.00 119.87 ? 163  ILE A CD1 1 
ATOM   1233  N  N   . ASN A 1 164 ? 168.918 198.772 182.286 1.00 131.62 ? 164  ASN A N   1 
ATOM   1234  C  CA  . ASN A 1 164 ? 168.159 199.713 181.466 1.00 131.62 ? 164  ASN A CA  1 
ATOM   1235  C  C   . ASN A 1 164 ? 168.942 200.989 181.178 1.00 131.62 ? 164  ASN A C   1 
ATOM   1236  O  O   . ASN A 1 164 ? 170.060 201.171 181.672 1.00 131.62 ? 164  ASN A O   1 
ATOM   1237  C  CB  . ASN A 1 164 ? 166.822 200.052 182.133 1.00 131.62 ? 164  ASN A CB  1 
ATOM   1238  C  CG  . ASN A 1 164 ? 165.673 200.097 181.146 1.00 131.62 ? 164  ASN A CG  1 
ATOM   1239  O  OD1 . ASN A 1 164 ? 165.874 200.302 179.949 1.00 131.62 ? 164  ASN A OD1 1 
ATOM   1240  N  ND2 . ASN A 1 164 ? 164.458 199.900 181.645 1.00 131.62 ? 164  ASN A ND2 1 
ATOM   1241  N  N   . ASP A 1 165 ? 168.359 201.873 180.366 1.00 135.67 ? 165  ASP A N   1 
ATOM   1242  C  CA  . ASP A 1 165 ? 169.019 203.126 180.016 1.00 135.67 ? 165  ASP A CA  1 
ATOM   1243  C  C   . ASP A 1 165 ? 168.959 204.146 181.145 1.00 135.67 ? 165  ASP A C   1 
ATOM   1244  O  O   . ASP A 1 165 ? 169.751 205.095 181.157 1.00 135.67 ? 165  ASP A O   1 
ATOM   1245  C  CB  . ASP A 1 165 ? 168.392 203.710 178.749 1.00 135.67 ? 165  ASP A CB  1 
ATOM   1246  C  CG  . ASP A 1 165 ? 166.883 203.827 178.846 1.00 135.67 ? 165  ASP A CG  1 
ATOM   1247  O  OD1 . ASP A 1 165 ? 166.310 203.358 179.852 1.00 135.67 ? 165  ASP A OD1 1 
ATOM   1248  O  OD2 . ASP A 1 165 ? 166.268 204.387 177.914 1.00 135.67 ? 165  ASP A OD2 1 
ATOM   1249  N  N   . LYS A 1 166 ? 168.035 203.973 182.093 1.00 129.43 ? 166  LYS A N   1 
ATOM   1250  C  CA  . LYS A 1 166 ? 167.905 204.931 183.186 1.00 129.43 ? 166  LYS A CA  1 
ATOM   1251  C  C   . LYS A 1 166 ? 169.108 204.895 184.119 1.00 129.43 ? 166  LYS A C   1 
ATOM   1252  O  O   . LYS A 1 166 ? 169.310 205.826 184.906 1.00 129.43 ? 166  LYS A O   1 
ATOM   1253  C  CB  . LYS A 1 166 ? 166.619 204.662 183.969 1.00 129.43 ? 166  LYS A CB  1 
ATOM   1254  N  N   . GLY A 1 167 ? 169.913 203.839 184.051 1.00 123.23 ? 167  GLY A N   1 
ATOM   1255  C  CA  . GLY A 1 167 ? 171.052 203.695 184.930 1.00 123.23 ? 167  GLY A CA  1 
ATOM   1256  C  C   . GLY A 1 167 ? 170.762 203.023 186.251 1.00 123.23 ? 167  GLY A C   1 
ATOM   1257  O  O   . GLY A 1 167 ? 171.623 203.047 187.140 1.00 123.23 ? 167  GLY A O   1 
ATOM   1258  N  N   . GLU A 1 168 ? 169.581 202.433 186.413 1.00 121.21 ? 168  GLU A N   1 
ATOM   1259  C  CA  . GLU A 1 168 ? 169.241 201.751 187.653 1.00 121.21 ? 168  GLU A CA  1 
ATOM   1260  C  C   . GLU A 1 168 ? 170.140 200.539 187.865 1.00 121.21 ? 168  GLU A C   1 
ATOM   1261  O  O   . GLU A 1 168 ? 170.515 199.839 186.920 1.00 121.21 ? 168  GLU A O   1 
ATOM   1262  C  CB  . GLU A 1 168 ? 167.774 201.320 187.640 1.00 121.21 ? 168  GLU A CB  1 
ATOM   1263  N  N   . ASN A 1 169 ? 170.489 200.299 189.124 1.00 113.05 ? 169  ASN A N   1 
ATOM   1264  C  CA  . ASN A 1 169 ? 171.392 199.219 189.492 1.00 113.05 ? 169  ASN A CA  1 
ATOM   1265  C  C   . ASN A 1 169 ? 170.625 198.088 190.162 1.00 113.05 ? 169  ASN A C   1 
ATOM   1266  O  O   . ASN A 1 169 ? 169.768 198.324 191.018 1.00 113.05 ? 169  ASN A O   1 
ATOM   1267  C  CB  . ASN A 1 169 ? 172.490 199.725 190.427 1.00 113.05 ? 169  ASN A CB  1 
ATOM   1268  C  CG  . ASN A 1 169 ? 173.564 200.497 189.694 1.00 113.05 ? 169  ASN A CG  1 
ATOM   1269  O  OD1 . ASN A 1 169 ? 173.538 200.610 188.469 1.00 113.05 ? 169  ASN A OD1 1 
ATOM   1270  N  ND2 . ASN A 1 169 ? 174.516 201.037 190.442 1.00 113.05 ? 169  ASN A ND2 1 
ATOM   1271  N  N   . GLY A 1 170 ? 170.942 196.860 189.765 1.00 98.21  ? 170  GLY A N   1 
ATOM   1272  C  CA  . GLY A 1 170 ? 170.364 195.666 190.336 1.00 98.21  ? 170  GLY A CA  1 
ATOM   1273  C  C   . GLY A 1 170 ? 171.449 194.695 190.763 1.00 98.21  ? 170  GLY A C   1 
ATOM   1274  O  O   . GLY A 1 170 ? 172.564 195.084 191.115 1.00 98.21  ? 170  GLY A O   1 
ATOM   1275  N  N   . TRP A 1 171 ? 171.101 193.409 190.728 1.00 85.28  ? 171  TRP A N   1 
ATOM   1276  C  CA  . TRP A 1 171 ? 172.031 192.337 191.088 1.00 85.28  ? 171  TRP A CA  1 
ATOM   1277  C  C   . TRP A 1 171 ? 171.850 191.217 190.064 1.00 85.28  ? 171  TRP A C   1 
ATOM   1278  O  O   . TRP A 1 171 ? 171.019 190.323 190.242 1.00 85.28  ? 171  TRP A O   1 
ATOM   1279  C  CB  . TRP A 1 171 ? 171.792 191.856 192.512 1.00 85.28  ? 171  TRP A CB  1 
ATOM   1280  C  CG  . TRP A 1 171 ? 172.303 192.808 193.551 1.00 85.28  ? 171  TRP A CG  1 
ATOM   1281  C  CD1 . TRP A 1 171 ? 171.555 193.599 194.373 1.00 85.28  ? 171  TRP A CD1 1 
ATOM   1282  C  CD2 . TRP A 1 171 ? 173.673 193.081 193.869 1.00 85.28  ? 171  TRP A CD2 1 
ATOM   1283  N  NE1 . TRP A 1 171 ? 172.374 194.342 195.188 1.00 85.28  ? 171  TRP A NE1 1 
ATOM   1284  C  CE2 . TRP A 1 171 ? 173.679 194.043 194.898 1.00 85.28  ? 171  TRP A CE2 1 
ATOM   1285  C  CE3 . TRP A 1 171 ? 174.895 192.604 193.386 1.00 85.28  ? 171  TRP A CE3 1 
ATOM   1286  C  CZ2 . TRP A 1 171 ? 174.857 194.535 195.453 1.00 85.28  ? 171  TRP A CZ2 1 
ATOM   1287  C  CZ3 . TRP A 1 171 ? 176.063 193.094 193.938 1.00 85.28  ? 171  TRP A CZ3 1 
ATOM   1288  C  CH2 . TRP A 1 171 ? 176.036 194.050 194.960 1.00 85.28  ? 171  TRP A CH2 1 
ATOM   1289  N  N   . LEU A 1 172 ? 172.635 191.277 188.992 1.00 83.41  ? 172  LEU A N   1 
ATOM   1290  C  CA  . LEU A 1 172 ? 172.530 190.320 187.901 1.00 83.41  ? 172  LEU A CA  1 
ATOM   1291  C  C   . LEU A 1 172 ? 173.301 189.050 188.228 1.00 83.41  ? 172  LEU A C   1 
ATOM   1292  O  O   . LEU A 1 172 ? 174.413 189.102 188.762 1.00 83.41  ? 172  LEU A O   1 
ATOM   1293  C  CB  . LEU A 1 172 ? 173.059 190.923 186.598 1.00 83.41  ? 172  LEU A CB  1 
ATOM   1294  C  CG  . LEU A 1 172 ? 172.080 191.702 185.716 1.00 83.41  ? 172  LEU A CG  1 
ATOM   1295  C  CD1 . LEU A 1 172 ? 170.928 190.812 185.275 1.00 83.41  ? 172  LEU A CD1 1 
ATOM   1296  C  CD2 . LEU A 1 172 ? 171.564 192.946 186.423 1.00 83.41  ? 172  LEU A CD2 1 
ATOM   1297  N  N   . GLU A 1 173 ? 172.701 187.907 187.904 1.00 82.50  ? 173  GLU A N   1 
ATOM   1298  C  CA  . GLU A 1 173 ? 173.358 186.609 188.037 1.00 82.50  ? 173  GLU A CA  1 
ATOM   1299  C  C   . GLU A 1 173 ? 173.996 186.276 186.695 1.00 82.50  ? 173  GLU A C   1 
ATOM   1300  O  O   . GLU A 1 173 ? 173.321 185.811 185.773 1.00 82.50  ? 173  GLU A O   1 
ATOM   1301  C  CB  . GLU A 1 173 ? 172.361 185.538 188.465 1.00 82.50  ? 173  GLU A CB  1 
ATOM   1302  C  CG  . GLU A 1 173 ? 171.756 185.755 189.844 1.00 82.50  ? 173  GLU A CG  1 
ATOM   1303  C  CD  . GLU A 1 173 ? 172.610 185.181 190.960 1.00 82.50  ? 173  GLU A CD  1 
ATOM   1304  O  OE1 . GLU A 1 173 ? 173.852 185.177 190.828 1.00 82.50  ? 173  GLU A OE1 1 
ATOM   1305  O  OE2 . GLU A 1 173 ? 172.036 184.731 191.973 1.00 82.50  ? 173  GLU A OE2 1 
ATOM   1306  N  N   . ILE A 1 174 ? 175.299 186.512 186.580 1.00 78.17  ? 174  ILE A N   1 
ATOM   1307  C  CA  . ILE A 1 174 ? 175.985 186.325 185.303 1.00 78.17  ? 174  ILE A CA  1 
ATOM   1308  C  C   . ILE A 1 174 ? 177.015 185.209 185.427 1.00 78.17  ? 174  ILE A C   1 
ATOM   1309  O  O   . ILE A 1 174 ? 177.564 184.992 186.516 1.00 78.17  ? 174  ILE A O   1 
ATOM   1310  C  CB  . ILE A 1 174 ? 176.643 187.630 184.827 1.00 78.17  ? 174  ILE A CB  1 
ATOM   1311  C  CG1 . ILE A 1 174 ? 177.753 188.055 185.789 1.00 78.17  ? 174  ILE A CG1 1 
ATOM   1312  C  CG2 . ILE A 1 174 ? 175.605 188.731 184.693 1.00 78.17  ? 174  ILE A CG2 1 
ATOM   1313  C  CD1 . ILE A 1 174 ? 178.719 189.060 185.201 1.00 78.17  ? 174  ILE A CD1 1 
ATOM   1314  N  N   . PRO A 1 175 ? 177.300 184.475 184.352 1.00 78.54  ? 175  PRO A N   1 
ATOM   1315  C  CA  . PRO A 1 175 ? 178.346 183.449 184.420 1.00 78.54  ? 175  PRO A CA  1 
ATOM   1316  C  C   . PRO A 1 175 ? 179.700 184.064 184.741 1.00 78.54  ? 175  PRO A C   1 
ATOM   1317  O  O   . PRO A 1 175 ? 179.989 185.207 184.381 1.00 78.54  ? 175  PRO A O   1 
ATOM   1318  C  CB  . PRO A 1 175 ? 178.330 182.827 183.019 1.00 78.54  ? 175  PRO A CB  1 
ATOM   1319  C  CG  . PRO A 1 175 ? 176.983 183.135 182.471 1.00 78.54  ? 175  PRO A CG  1 
ATOM   1320  C  CD  . PRO A 1 175 ? 176.538 184.423 183.093 1.00 78.54  ? 175  PRO A CD  1 
ATOM   1321  N  N   . ILE A 1 176 ? 180.533 183.284 185.435 1.00 79.31  ? 176  ILE A N   1 
ATOM   1322  C  CA  . ILE A 1 176 ? 181.815 183.787 185.917 1.00 79.31  ? 176  ILE A CA  1 
ATOM   1323  C  C   . ILE A 1 176 ? 182.742 184.191 184.780 1.00 79.31  ? 176  ILE A C   1 
ATOM   1324  O  O   . ILE A 1 176 ? 183.604 185.056 184.966 1.00 79.31  ? 176  ILE A O   1 
ATOM   1325  C  CB  . ILE A 1 176 ? 182.496 182.740 186.823 1.00 79.31  ? 176  ILE A CB  1 
ATOM   1326  C  CG1 . ILE A 1 176 ? 182.588 181.391 186.110 1.00 79.31  ? 176  ILE A CG1 1 
ATOM   1327  C  CG2 . ILE A 1 176 ? 181.745 182.603 188.134 1.00 79.31  ? 176  ILE A CG2 1 
ATOM   1328  C  CD1 . ILE A 1 176 ? 183.398 180.361 186.864 1.00 79.31  ? 176  ILE A CD1 1 
ATOM   1329  N  N   . ASP A 1 177 ? 182.592 183.585 183.600 1.00 87.53  ? 177  ASP A N   1 
ATOM   1330  C  CA  . ASP A 1 177 ? 183.469 183.917 182.483 1.00 87.53  ? 177  ASP A CA  1 
ATOM   1331  C  C   . ASP A 1 177 ? 183.230 185.324 181.950 1.00 87.53  ? 177  ASP A C   1 
ATOM   1332  O  O   . ASP A 1 177 ? 184.073 185.845 181.213 1.00 87.53  ? 177  ASP A O   1 
ATOM   1333  C  CB  . ASP A 1 177 ? 183.304 182.890 181.360 1.00 87.53  ? 177  ASP A CB  1 
ATOM   1334  C  CG  . ASP A 1 177 ? 181.876 182.793 180.860 1.00 87.53  ? 177  ASP A CG  1 
ATOM   1335  O  OD1 . ASP A 1 177 ? 180.992 183.456 181.439 1.00 87.53  ? 177  ASP A OD1 1 
ATOM   1336  O  OD2 . ASP A 1 177 ? 181.636 182.048 179.886 1.00 87.53  ? 177  ASP A OD2 1 
ATOM   1337  N  N   . GLN A 1 178 ? 182.109 185.949 182.306 1.00 84.68  ? 178  GLN A N   1 
ATOM   1338  C  CA  . GLN A 1 178 ? 181.804 187.304 181.867 1.00 84.68  ? 178  GLN A CA  1 
ATOM   1339  C  C   . GLN A 1 178 ? 182.378 188.372 182.790 1.00 84.68  ? 178  GLN A C   1 
ATOM   1340  O  O   . GLN A 1 178 ? 182.185 189.563 182.525 1.00 84.68  ? 178  GLN A O   1 
ATOM   1341  C  CB  . GLN A 1 178 ? 180.288 187.488 181.752 1.00 84.68  ? 178  GLN A CB  1 
ATOM   1342  C  CG  . GLN A 1 178 ? 179.649 186.687 180.631 1.00 84.68  ? 178  GLN A CG  1 
ATOM   1343  C  CD  . GLN A 1 178 ? 178.150 186.899 180.546 1.00 84.68  ? 178  GLN A CD  1 
ATOM   1344  O  OE1 . GLN A 1 178 ? 177.643 187.967 180.890 1.00 84.68  ? 178  GLN A OE1 1 
ATOM   1345  N  NE2 . GLN A 1 178 ? 177.433 185.881 180.087 1.00 84.68  ? 178  GLN A NE2 1 
ATOM   1346  N  N   . LEU A 1 179 ? 183.068 187.980 183.858 1.00 85.35  ? 179  LEU A N   1 
ATOM   1347  C  CA  . LEU A 1 179 ? 183.614 188.942 184.806 1.00 85.35  ? 179  LEU A CA  1 
ATOM   1348  C  C   . LEU A 1 179 ? 184.784 189.695 184.186 1.00 85.35  ? 179  LEU A C   1 
ATOM   1349  O  O   . LEU A 1 179 ? 185.577 189.118 183.434 1.00 85.35  ? 179  LEU A O   1 
ATOM   1350  C  CB  . LEU A 1 179 ? 184.056 188.232 186.083 1.00 85.35  ? 179  LEU A CB  1 
ATOM   1351  C  CG  . LEU A 1 179 ? 182.939 187.733 186.999 1.00 85.35  ? 179  LEU A CG  1 
ATOM   1352  C  CD1 . LEU A 1 179 ? 183.524 187.057 188.226 1.00 85.35  ? 179  LEU A CD1 1 
ATOM   1353  C  CD2 . LEU A 1 179 ? 182.026 188.878 187.398 1.00 85.35  ? 179  LEU A CD2 1 
ATOM   1354  N  N   . VAL A 1 180 ? 184.888 190.982 184.499 1.00 91.18  ? 180  VAL A N   1 
ATOM   1355  C  CA  . VAL A 1 180 ? 185.999 191.817 184.050 1.00 91.18  ? 180  VAL A CA  1 
ATOM   1356  C  C   . VAL A 1 180 ? 186.695 192.386 185.281 1.00 91.18  ? 180  VAL A C   1 
ATOM   1357  O  O   . VAL A 1 180 ? 186.079 192.464 186.354 1.00 91.18  ? 180  VAL A O   1 
ATOM   1358  C  CB  . VAL A 1 180 ? 185.515 192.934 183.111 1.00 91.18  ? 180  VAL A CB  1 
ATOM   1359  C  CG1 . VAL A 1 180 ? 184.701 192.350 181.968 1.00 91.18  ? 180  VAL A CG1 1 
ATOM   1360  C  CG2 . VAL A 1 180 ? 184.702 193.965 183.881 1.00 91.18  ? 180  VAL A CG2 1 
ATOM   1361  N  N   . PRO A 1 181 ? 187.968 192.771 185.191 1.00 92.33  ? 181  PRO A N   1 
ATOM   1362  C  CA  . PRO A 1 181 ? 188.626 193.391 186.346 1.00 92.33  ? 181  PRO A CA  1 
ATOM   1363  C  C   . PRO A 1 181 ? 187.941 194.689 186.742 1.00 92.33  ? 181  PRO A C   1 
ATOM   1364  O  O   . PRO A 1 181 ? 187.376 195.401 185.909 1.00 92.33  ? 181  PRO A O   1 
ATOM   1365  C  CB  . PRO A 1 181 ? 190.055 193.641 185.851 1.00 92.33  ? 181  PRO A CB  1 
ATOM   1366  C  CG  . PRO A 1 181 ? 190.248 192.654 184.759 1.00 92.33  ? 181  PRO A CG  1 
ATOM   1367  C  CD  . PRO A 1 181 ? 188.912 192.539 184.085 1.00 92.33  ? 181  PRO A CD  1 
ATOM   1368  N  N   . GLY A 1 182 ? 188.001 194.992 188.033 1.00 99.26  ? 182  GLY A N   1 
ATOM   1369  C  CA  . GLY A 1 182 ? 187.307 196.153 188.557 1.00 99.26  ? 182  GLY A CA  1 
ATOM   1370  C  C   . GLY A 1 182 ? 185.800 196.029 188.525 1.00 99.26  ? 182  GLY A C   1 
ATOM   1371  O  O   . GLY A 1 182 ? 185.108 197.000 188.194 1.00 99.26  ? 182  GLY A O   1 
ATOM   1372  N  N   . ASP A 1 183 ? 185.273 194.855 188.858 1.00 93.42  ? 183  ASP A N   1 
ATOM   1373  C  CA  . ASP A 1 183 ? 183.840 194.622 188.921 1.00 93.42  ? 183  ASP A CA  1 
ATOM   1374  C  C   . ASP A 1 183 ? 183.450 194.271 190.351 1.00 93.42  ? 183  ASP A C   1 
ATOM   1375  O  O   . ASP A 1 183 ? 184.139 193.505 191.030 1.00 93.42  ? 183  ASP A O   1 
ATOM   1376  C  CB  . ASP A 1 183 ? 183.422 193.497 187.968 1.00 93.42  ? 183  ASP A CB  1 
ATOM   1377  C  CG  . ASP A 1 183 ? 181.916 193.380 187.823 1.00 93.42  ? 183  ASP A CG  1 
ATOM   1378  O  OD1 . ASP A 1 183 ? 181.182 194.147 188.480 1.00 93.42  ? 183  ASP A OD1 1 
ATOM   1379  O  OD2 . ASP A 1 183 ? 181.466 192.516 187.043 1.00 93.42  ? 183  ASP A OD2 1 
ATOM   1380  N  N   . ILE A 1 184 ? 182.338 194.841 190.804 1.00 86.78  ? 184  ILE A N   1 
ATOM   1381  C  CA  . ILE A 1 184 ? 181.876 194.686 192.178 1.00 86.78  ? 184  ILE A CA  1 
ATOM   1382  C  C   . ILE A 1 184 ? 180.911 193.511 192.232 1.00 86.78  ? 184  ILE A C   1 
ATOM   1383  O  O   . ILE A 1 184 ? 179.923 193.470 191.489 1.00 86.78  ? 184  ILE A O   1 
ATOM   1384  C  CB  . ILE A 1 184 ? 181.212 195.970 192.695 1.00 86.78  ? 184  ILE A CB  1 
ATOM   1385  C  CG1 . ILE A 1 184 ? 182.191 197.142 192.623 1.00 86.78  ? 184  ILE A CG1 1 
ATOM   1386  C  CG2 . ILE A 1 184 ? 180.717 195.776 194.119 1.00 86.78  ? 184  ILE A CG2 1 
ATOM   1387  C  CD1 . ILE A 1 184 ? 181.564 198.482 192.933 1.00 86.78  ? 184  ILE A CD1 1 
ATOM   1388  N  N   . ILE A 1 185 ? 181.197 192.553 193.114 1.00 77.47  ? 185  ILE A N   1 
ATOM   1389  C  CA  . ILE A 1 185 ? 180.352 191.385 193.316 1.00 77.47  ? 185  ILE A CA  1 
ATOM   1390  C  C   . ILE A 1 185 ? 180.067 191.250 194.805 1.00 77.47  ? 185  ILE A C   1 
ATOM   1391  O  O   . ILE A 1 185 ? 180.716 191.874 195.646 1.00 77.47  ? 185  ILE A O   1 
ATOM   1392  C  CB  . ILE A 1 185 ? 180.989 190.089 192.774 1.00 77.47  ? 185  ILE A CB  1 
ATOM   1393  C  CG1 . ILE A 1 185 ? 182.146 189.647 193.669 1.00 77.47  ? 185  ILE A CG1 1 
ATOM   1394  C  CG2 . ILE A 1 185 ? 181.477 190.282 191.352 1.00 77.47  ? 185  ILE A CG2 1 
ATOM   1395  C  CD1 . ILE A 1 185 ? 182.780 188.347 193.235 1.00 77.47  ? 185  ILE A CD1 1 
ATOM   1396  N  N   . LYS A 1 186 ? 179.070 190.428 195.124 1.00 75.38  ? 186  LYS A N   1 
ATOM   1397  C  CA  . LYS A 1 186 ? 178.737 190.113 196.504 1.00 75.38  ? 186  LYS A CA  1 
ATOM   1398  C  C   . LYS A 1 186 ? 178.868 188.613 196.718 1.00 75.38  ? 186  LYS A C   1 
ATOM   1399  O  O   . LYS A 1 186 ? 178.597 187.817 195.814 1.00 75.38  ? 186  LYS A O   1 
ATOM   1400  C  CB  . LYS A 1 186 ? 177.324 190.589 196.878 1.00 75.38  ? 186  LYS A CB  1 
ATOM   1401  C  CG  . LYS A 1 186 ? 176.189 189.738 196.341 1.00 75.38  ? 186  LYS A CG  1 
ATOM   1402  C  CD  . LYS A 1 186 ? 174.898 190.032 197.089 1.00 75.38  ? 186  LYS A CD  1 
ATOM   1403  C  CE  . LYS A 1 186 ? 173.711 189.333 196.450 1.00 75.38  ? 186  LYS A CE  1 
ATOM   1404  N  NZ  . LYS A 1 186 ? 172.419 189.815 197.010 1.00 75.38  ? 186  LYS A NZ  1 
ATOM   1405  N  N   . LEU A 1 187 ? 179.300 188.239 197.917 1.00 65.93  ? 187  LEU A N   1 
ATOM   1406  C  CA  . LEU A 1 187 ? 179.600 186.863 198.272 1.00 65.93  ? 187  LEU A CA  1 
ATOM   1407  C  C   . LEU A 1 187 ? 178.740 186.440 199.452 1.00 65.93  ? 187  LEU A C   1 
ATOM   1408  O  O   . LEU A 1 187 ? 178.635 187.167 200.447 1.00 65.93  ? 187  LEU A O   1 
ATOM   1409  C  CB  . LEU A 1 187 ? 181.078 186.704 198.631 1.00 65.93  ? 187  LEU A CB  1 
ATOM   1410  C  CG  . LEU A 1 187 ? 182.092 187.040 197.541 1.00 65.93  ? 187  LEU A CG  1 
ATOM   1411  C  CD1 . LEU A 1 187 ? 183.495 187.000 198.114 1.00 65.93  ? 187  LEU A CD1 1 
ATOM   1412  C  CD2 . LEU A 1 187 ? 181.960 186.082 196.370 1.00 65.93  ? 187  LEU A CD2 1 
ATOM   1413  N  N   . ALA A 1 188 ? 178.136 185.261 199.337 1.00 62.61  ? 188  ALA A N   1 
ATOM   1414  C  CA  . ALA A 1 188 ? 177.331 184.667 200.393 1.00 62.61  ? 188  ALA A CA  1 
ATOM   1415  C  C   . ALA A 1 188 ? 177.873 183.276 200.702 1.00 62.61  ? 188  ALA A C   1 
ATOM   1416  O  O   . ALA A 1 188 ? 178.887 182.843 200.147 1.00 62.61  ? 188  ALA A O   1 
ATOM   1417  C  CB  . ALA A 1 188 ? 175.851 184.609 199.998 1.00 62.61  ? 188  ALA A CB  1 
ATOM   1418  N  N   . ALA A 1 189 ? 177.186 182.572 201.597 1.00 58.57  ? 189  ALA A N   1 
ATOM   1419  C  CA  . ALA A 1 189 ? 177.623 181.242 201.995 1.00 58.57  ? 189  ALA A CA  1 
ATOM   1420  C  C   . ALA A 1 189 ? 177.490 180.259 200.840 1.00 58.57  ? 189  ALA A C   1 
ATOM   1421  O  O   . ALA A 1 189 ? 176.468 180.216 200.151 1.00 58.57  ? 189  ALA A O   1 
ATOM   1422  C  CB  . ALA A 1 189 ? 176.811 180.753 203.193 1.00 58.57  ? 189  ALA A CB  1 
ATOM   1423  N  N   . GLY A 1 190 ? 178.537 179.465 200.631 1.00 57.03  ? 190  GLY A N   1 
ATOM   1424  C  CA  . GLY A 1 190 ? 178.528 178.435 199.615 1.00 57.03  ? 190  GLY A CA  1 
ATOM   1425  C  C   . GLY A 1 190 ? 178.961 178.873 198.233 1.00 57.03  ? 190  GLY A C   1 
ATOM   1426  O  O   . GLY A 1 190 ? 179.089 178.020 197.346 1.00 57.03  ? 190  GLY A O   1 
ATOM   1427  N  N   . ASP A 1 191 ? 179.191 180.165 198.017 1.00 59.80  ? 191  ASP A N   1 
ATOM   1428  C  CA  . ASP A 1 191 ? 179.619 180.664 196.718 1.00 59.80  ? 191  ASP A CA  1 
ATOM   1429  C  C   . ASP A 1 191 ? 181.140 180.673 196.643 1.00 59.80  ? 191  ASP A C   1 
ATOM   1430  O  O   . ASP A 1 191 ? 181.806 181.271 197.494 1.00 59.80  ? 191  ASP A O   1 
ATOM   1431  C  CB  . ASP A 1 191 ? 179.070 182.070 196.471 1.00 59.80  ? 191  ASP A CB  1 
ATOM   1432  C  CG  . ASP A 1 191 ? 177.560 182.090 196.329 1.00 59.80  ? 191  ASP A CG  1 
ATOM   1433  O  OD1 . ASP A 1 191 ? 176.990 181.082 195.858 1.00 59.80  ? 191  ASP A OD1 1 
ATOM   1434  O  OD2 . ASP A 1 191 ? 176.942 183.115 196.684 1.00 59.80  ? 191  ASP A OD2 1 
ATOM   1435  N  N   . MET A 1 192 ? 181.685 180.011 195.626 1.00 61.69  ? 192  MET A N   1 
ATOM   1436  C  CA  . MET A 1 192 ? 183.127 179.982 195.441 1.00 61.69  ? 192  MET A CA  1 
ATOM   1437  C  C   . MET A 1 192 ? 183.626 181.330 194.938 1.00 61.69  ? 192  MET A C   1 
ATOM   1438  O  O   . MET A 1 192 ? 182.876 182.121 194.357 1.00 61.69  ? 192  MET A O   1 
ATOM   1439  C  CB  . MET A 1 192 ? 183.533 178.886 194.457 1.00 61.69  ? 192  MET A CB  1 
ATOM   1440  C  CG  . MET A 1 192 ? 183.418 179.289 192.995 1.00 61.69  ? 192  MET A CG  1 
ATOM   1441  S  SD  . MET A 1 192 ? 184.034 178.025 191.867 1.00 61.69  ? 192  MET A SD  1 
ATOM   1442  C  CE  . MET A 1 192 ? 185.790 178.094 192.211 1.00 61.69  ? 192  MET A CE  1 
ATOM   1443  N  N   . ILE A 1 193 ? 184.908 181.588 195.170 1.00 68.17  ? 193  ILE A N   1 
ATOM   1444  C  CA  . ILE A 1 193 ? 185.539 182.822 194.715 1.00 68.17  ? 193  ILE A CA  1 
ATOM   1445  C  C   . ILE A 1 193 ? 185.806 182.697 193.220 1.00 68.17  ? 193  ILE A C   1 
ATOM   1446  O  O   . ILE A 1 193 ? 186.540 181.793 192.795 1.00 68.17  ? 193  ILE A O   1 
ATOM   1447  C  CB  . ILE A 1 193 ? 186.828 183.105 195.499 1.00 68.17  ? 193  ILE A CB  1 
ATOM   1448  C  CG1 . ILE A 1 193 ? 186.547 183.088 197.000 1.00 68.17  ? 193  ILE A CG1 1 
ATOM   1449  C  CG2 . ILE A 1 193 ? 187.408 184.439 195.096 1.00 68.17  ? 193  ILE A CG2 1 
ATOM   1450  C  CD1 . ILE A 1 193 ? 185.499 184.078 197.428 1.00 68.17  ? 193  ILE A CD1 1 
ATOM   1451  N  N   . PRO A 1 194 ? 185.243 183.573 192.389 1.00 70.44  ? 194  PRO A N   1 
ATOM   1452  C  CA  . PRO A 1 194 ? 185.375 183.400 190.936 1.00 70.44  ? 194  PRO A CA  1 
ATOM   1453  C  C   . PRO A 1 194 ? 186.693 183.923 190.386 1.00 70.44  ? 194  PRO A C   1 
ATOM   1454  O  O   . PRO A 1 194 ? 187.168 183.452 189.348 1.00 70.44  ? 194  PRO A O   1 
ATOM   1455  C  CB  . PRO A 1 194 ? 184.183 184.190 190.374 1.00 70.44  ? 194  PRO A CB  1 
ATOM   1456  C  CG  . PRO A 1 194 ? 183.532 184.886 191.553 1.00 70.44  ? 194  PRO A CG  1 
ATOM   1457  C  CD  . PRO A 1 194 ? 184.426 184.743 192.737 1.00 70.44  ? 194  PRO A CD  1 
ATOM   1458  N  N   . ALA A 1 195 ? 187.290 184.893 191.071 1.00 77.32  ? 195  ALA A N   1 
ATOM   1459  C  CA  . ALA A 1 195 ? 188.543 185.492 190.633 1.00 77.32  ? 195  ALA A CA  1 
ATOM   1460  C  C   . ALA A 1 195 ? 189.156 186.228 191.813 1.00 77.32  ? 195  ALA A C   1 
ATOM   1461  O  O   . ALA A 1 195 ? 188.567 186.306 192.892 1.00 77.32  ? 195  ALA A O   1 
ATOM   1462  C  CB  . ALA A 1 195 ? 188.330 186.434 189.445 1.00 77.32  ? 195  ALA A CB  1 
ATOM   1463  N  N   . ASP A 1 196 ? 190.355 186.765 191.597 1.00 87.97  ? 196  ASP A N   1 
ATOM   1464  C  CA  . ASP A 1 196 ? 191.027 187.524 192.643 1.00 87.97  ? 196  ASP A CA  1 
ATOM   1465  C  C   . ASP A 1 196 ? 190.167 188.709 193.063 1.00 87.97  ? 196  ASP A C   1 
ATOM   1466  O  O   . ASP A 1 196 ? 189.678 189.467 192.221 1.00 87.97  ? 196  ASP A O   1 
ATOM   1467  C  CB  . ASP A 1 196 ? 192.393 188.002 192.153 1.00 87.97  ? 196  ASP A CB  1 
ATOM   1468  C  CG  . ASP A 1 196 ? 193.409 186.881 192.083 1.00 87.97  ? 196  ASP A CG  1 
ATOM   1469  O  OD1 . ASP A 1 196 ? 193.247 185.887 192.820 1.00 87.97  ? 196  ASP A OD1 1 
ATOM   1470  O  OD2 . ASP A 1 196 ? 194.367 186.992 191.290 1.00 87.97  ? 196  ASP A OD2 1 
ATOM   1471  N  N   . LEU A 1 197 ? 189.983 188.868 194.371 1.00 84.55  ? 197  LEU A N   1 
ATOM   1472  C  CA  . LEU A 1 197 ? 189.045 189.840 194.909 1.00 84.55  ? 197  LEU A CA  1 
ATOM   1473  C  C   . LEU A 1 197 ? 189.715 190.702 195.967 1.00 84.55  ? 197  LEU A C   1 
ATOM   1474  O  O   . LEU A 1 197 ? 190.569 190.235 196.725 1.00 84.55  ? 197  LEU A O   1 
ATOM   1475  C  CB  . LEU A 1 197 ? 187.819 189.151 195.521 1.00 84.55  ? 197  LEU A CB  1 
ATOM   1476  C  CG  . LEU A 1 197 ? 186.855 188.466 194.555 1.00 84.55  ? 197  LEU A CG  1 
ATOM   1477  C  CD1 . LEU A 1 197 ? 185.718 187.816 195.320 1.00 84.55  ? 197  LEU A CD1 1 
ATOM   1478  C  CD2 . LEU A 1 197 ? 186.320 189.460 193.544 1.00 84.55  ? 197  LEU A CD2 1 
ATOM   1479  N  N   . ARG A 1 198 ? 189.312 191.969 196.009 1.00 93.17  ? 198  ARG A N   1 
ATOM   1480  C  CA  . ARG A 1 198 ? 189.673 192.886 197.083 1.00 93.17  ? 198  ARG A CA  1 
ATOM   1481  C  C   . ARG A 1 198 ? 188.417 193.156 197.896 1.00 93.17  ? 198  ARG A C   1 
ATOM   1482  O  O   . ARG A 1 198 ? 187.433 193.682 197.365 1.00 93.17  ? 198  ARG A O   1 
ATOM   1483  C  CB  . ARG A 1 198 ? 190.253 194.190 196.531 1.00 93.17  ? 198  ARG A CB  1 
ATOM   1484  C  CG  . ARG A 1 198 ? 190.473 195.269 197.579 1.00 93.17  ? 198  ARG A CG  1 
ATOM   1485  C  CD  . ARG A 1 198 ? 191.705 194.979 198.420 1.00 93.17  ? 198  ARG A CD  1 
ATOM   1486  N  NE  . ARG A 1 198 ? 192.052 196.100 199.285 1.00 93.17  ? 198  ARG A NE  1 
ATOM   1487  C  CZ  . ARG A 1 198 ? 191.453 196.372 200.436 1.00 93.17  ? 198  ARG A CZ  1 
ATOM   1488  N  NH1 . ARG A 1 198 ? 190.472 195.615 200.900 1.00 93.17  ? 198  ARG A NH1 1 
ATOM   1489  N  NH2 . ARG A 1 198 ? 191.849 197.428 201.140 1.00 93.17  ? 198  ARG A NH2 1 
ATOM   1490  N  N   . ILE A 1 199 ? 188.452 192.803 199.179 1.00 88.48  ? 199  ILE A N   1 
ATOM   1491  C  CA  . ILE A 1 199 ? 187.250 192.865 200.003 1.00 88.48  ? 199  ILE A CA  1 
ATOM   1492  C  C   . ILE A 1 199 ? 186.942 194.318 200.336 1.00 88.48  ? 199  ILE A C   1 
ATOM   1493  O  O   . ILE A 1 199 ? 187.719 194.993 201.021 1.00 88.48  ? 199  ILE A O   1 
ATOM   1494  C  CB  . ILE A 1 199 ? 187.416 192.026 201.275 1.00 88.48  ? 199  ILE A CB  1 
ATOM   1495  C  CG1 . ILE A 1 199 ? 187.561 190.545 200.922 1.00 88.48  ? 199  ILE A CG1 1 
ATOM   1496  C  CG2 . ILE A 1 199 ? 186.233 192.235 202.204 1.00 88.48  ? 199  ILE A CG2 1 
ATOM   1497  C  CD1 . ILE A 1 199 ? 186.290 189.920 200.393 1.00 88.48  ? 199  ILE A CD1 1 
ATOM   1498  N  N   . LEU A 1 200 ? 185.800 194.806 199.853 1.00 87.11  ? 200  LEU A N   1 
ATOM   1499  C  CA  . LEU A 1 200 ? 185.334 196.144 200.195 1.00 87.11  ? 200  LEU A CA  1 
ATOM   1500  C  C   . LEU A 1 200 ? 184.657 196.166 201.561 1.00 87.11  ? 200  LEU A C   1 
ATOM   1501  O  O   . LEU A 1 200 ? 184.924 197.055 202.375 1.00 87.11  ? 200  LEU A O   1 
ATOM   1502  C  CB  . LEU A 1 200 ? 184.378 196.663 199.117 1.00 87.11  ? 200  LEU A CB  1 
ATOM   1503  C  CG  . LEU A 1 200 ? 184.953 196.780 197.706 1.00 87.11  ? 200  LEU A CG  1 
ATOM   1504  C  CD1 . LEU A 1 200 ? 184.009 197.557 196.805 1.00 87.11  ? 200  LEU A CD1 1 
ATOM   1505  C  CD2 . LEU A 1 200 ? 186.321 197.438 197.743 1.00 87.11  ? 200  LEU A CD2 1 
ATOM   1506  N  N   . GLN A 1 201 ? 183.780 195.200 201.822 1.00 83.76  ? 201  GLN A N   1 
ATOM   1507  C  CA  . GLN A 1 201 ? 183.160 195.067 203.132 1.00 83.76  ? 201  GLN A CA  1 
ATOM   1508  C  C   . GLN A 1 201 ? 182.912 193.593 203.410 1.00 83.76  ? 201  GLN A C   1 
ATOM   1509  O  O   . GLN A 1 201 ? 182.721 192.798 202.487 1.00 83.76  ? 201  GLN A O   1 
ATOM   1510  C  CB  . GLN A 1 201 ? 181.850 195.858 203.225 1.00 83.76  ? 201  GLN A CB  1 
ATOM   1511  C  CG  . GLN A 1 201 ? 180.879 195.590 202.091 1.00 83.76  ? 201  GLN A CG  1 
ATOM   1512  C  CD  . GLN A 1 201 ? 179.457 195.979 202.439 1.00 83.76  ? 201  GLN A CD  1 
ATOM   1513  O  OE1 . GLN A 1 201 ? 178.898 195.513 203.431 1.00 83.76  ? 201  GLN A OE1 1 
ATOM   1514  N  NE2 . GLN A 1 201 ? 178.862 196.840 201.620 1.00 83.76  ? 201  GLN A NE2 1 
ATOM   1515  N  N   . ALA A 1 202 ? 182.908 193.236 204.693 1.00 80.41  ? 202  ALA A N   1 
ATOM   1516  C  CA  . ALA A 1 202 ? 182.762 191.842 205.090 1.00 80.41  ? 202  ALA A CA  1 
ATOM   1517  C  C   . ALA A 1 202 ? 182.071 191.759 206.441 1.00 80.41  ? 202  ALA A C   1 
ATOM   1518  O  O   . ALA A 1 202 ? 182.442 192.473 207.377 1.00 80.41  ? 202  ALA A O   1 
ATOM   1519  C  CB  . ALA A 1 202 ? 184.123 191.142 205.149 1.00 80.41  ? 202  ALA A CB  1 
ATOM   1520  N  N   . ARG A 1 203 ? 181.070 190.888 206.532 1.00 78.40  ? 203  ARG A N   1 
ATOM   1521  C  CA  . ARG A 1 203 ? 180.353 190.596 207.768 1.00 78.40  ? 203  ARG A CA  1 
ATOM   1522  C  C   . ARG A 1 203 ? 180.599 189.126 208.099 1.00 78.40  ? 203  ARG A C   1 
ATOM   1523  O  O   . ARG A 1 203 ? 179.985 188.234 207.500 1.00 78.40  ? 203  ARG A O   1 
ATOM   1524  C  CB  . ARG A 1 203 ? 178.865 190.901 207.617 1.00 78.40  ? 203  ARG A CB  1 
ATOM   1525  C  CG  . ARG A 1 203 ? 178.057 190.749 208.895 1.00 78.40  ? 203  ARG A CG  1 
ATOM   1526  C  CD  . ARG A 1 203 ? 178.394 191.834 209.903 1.00 78.40  ? 203  ARG A CD  1 
ATOM   1527  N  NE  . ARG A 1 203 ? 177.661 191.659 211.151 1.00 78.40  ? 203  ARG A NE  1 
ATOM   1528  C  CZ  . ARG A 1 203 ? 178.064 190.891 212.155 1.00 78.40  ? 203  ARG A CZ  1 
ATOM   1529  N  NH1 . ARG A 1 203 ? 179.197 190.211 212.093 1.00 78.40  ? 203  ARG A NH1 1 
ATOM   1530  N  NH2 . ARG A 1 203 ? 177.312 190.805 213.248 1.00 78.40  ? 203  ARG A NH2 1 
ATOM   1531  N  N   . ASP A 1 204 ? 181.515 188.889 209.040 1.00 71.92  ? 204  ASP A N   1 
ATOM   1532  C  CA  . ASP A 1 204 ? 181.839 187.553 209.542 1.00 71.92  ? 204  ASP A CA  1 
ATOM   1533  C  C   . ASP A 1 204 ? 182.187 186.595 208.405 1.00 71.92  ? 204  ASP A C   1 
ATOM   1534  O  O   . ASP A 1 204 ? 181.751 185.443 208.370 1.00 71.92  ? 204  ASP A O   1 
ATOM   1535  C  CB  . ASP A 1 204 ? 180.696 186.999 210.393 1.00 71.92  ? 204  ASP A CB  1 
ATOM   1536  C  CG  . ASP A 1 204 ? 180.790 187.428 211.843 1.00 71.92  ? 204  ASP A CG  1 
ATOM   1537  O  OD1 . ASP A 1 204 ? 181.873 187.265 212.443 1.00 71.92  ? 204  ASP A OD1 1 
ATOM   1538  O  OD2 . ASP A 1 204 ? 179.782 187.927 212.383 1.00 71.92  ? 204  ASP A OD2 1 
ATOM   1539  N  N   . LEU A 1 205 ? 182.997 187.081 207.468 1.00 69.79  ? 205  LEU A N   1 
ATOM   1540  C  CA  . LEU A 1 205 ? 183.341 186.300 206.287 1.00 69.79  ? 205  LEU A CA  1 
ATOM   1541  C  C   . LEU A 1 205 ? 184.427 185.287 206.631 1.00 69.79  ? 205  LEU A C   1 
ATOM   1542  O  O   . LEU A 1 205 ? 185.573 185.661 206.900 1.00 69.79  ? 205  LEU A O   1 
ATOM   1543  C  CB  . LEU A 1 205 ? 183.801 187.215 205.156 1.00 69.79  ? 205  LEU A CB  1 
ATOM   1544  C  CG  . LEU A 1 205 ? 183.986 186.518 203.808 1.00 69.79  ? 205  LEU A CG  1 
ATOM   1545  C  CD1 . LEU A 1 205 ? 182.634 186.215 203.191 1.00 69.79  ? 205  LEU A CD1 1 
ATOM   1546  C  CD2 . LEU A 1 205 ? 184.826 187.361 202.866 1.00 69.79  ? 205  LEU A CD2 1 
ATOM   1547  N  N   . PHE A 1 206 ? 184.061 184.007 206.624 1.00 63.56  ? 206  PHE A N   1 
ATOM   1548  C  CA  . PHE A 1 206 ? 184.993 182.902 206.791 1.00 63.56  ? 206  PHE A CA  1 
ATOM   1549  C  C   . PHE A 1 206 ? 185.022 182.104 205.497 1.00 63.56  ? 206  PHE A C   1 
ATOM   1550  O  O   . PHE A 1 206 ? 183.971 181.661 205.018 1.00 63.56  ? 206  PHE A O   1 
ATOM   1551  C  CB  . PHE A 1 206 ? 184.586 181.995 207.955 1.00 63.56  ? 206  PHE A CB  1 
ATOM   1552  C  CG  . PHE A 1 206 ? 184.901 182.559 209.310 1.00 63.56  ? 206  PHE A CG  1 
ATOM   1553  C  CD1 . PHE A 1 206 ? 184.018 183.421 209.938 1.00 63.56  ? 206  PHE A CD1 1 
ATOM   1554  C  CD2 . PHE A 1 206 ? 186.073 182.216 209.961 1.00 63.56  ? 206  PHE A CD2 1 
ATOM   1555  C  CE1 . PHE A 1 206 ? 184.301 183.934 211.188 1.00 63.56  ? 206  PHE A CE1 1 
ATOM   1556  C  CE2 . PHE A 1 206 ? 186.362 182.728 211.210 1.00 63.56  ? 206  PHE A CE2 1 
ATOM   1557  C  CZ  . PHE A 1 206 ? 185.476 183.588 211.823 1.00 63.56  ? 206  PHE A CZ  1 
ATOM   1558  N  N   . VAL A 1 207 ? 186.219 181.914 204.946 1.00 62.76  ? 207  VAL A N   1 
ATOM   1559  C  CA  . VAL A 1 207 ? 186.407 181.250 203.662 1.00 62.76  ? 207  VAL A CA  1 
ATOM   1560  C  C   . VAL A 1 207 ? 187.315 180.043 203.853 1.00 62.76  ? 207  VAL A C   1 
ATOM   1561  O  O   . VAL A 1 207 ? 188.144 180.016 204.768 1.00 62.76  ? 207  VAL A O   1 
ATOM   1562  C  CB  . VAL A 1 207 ? 186.992 182.209 202.604 1.00 62.76  ? 207  VAL A CB  1 
ATOM   1563  C  CG1 . VAL A 1 207 ? 186.073 183.403 202.404 1.00 62.76  ? 207  VAL A CG1 1 
ATOM   1564  C  CG2 . VAL A 1 207 ? 188.385 182.662 203.005 1.00 62.76  ? 207  VAL A CG2 1 
ATOM   1565  N  N   . ALA A 1 208 ? 187.157 179.044 202.987 1.00 64.09  ? 208  ALA A N   1 
ATOM   1566  C  CA  . ALA A 1 208 ? 187.949 177.817 203.040 1.00 64.09  ? 208  ALA A CA  1 
ATOM   1567  C  C   . ALA A 1 208 ? 189.055 177.910 201.995 1.00 64.09  ? 208  ALA A C   1 
ATOM   1568  O  O   . ALA A 1 208 ? 188.793 177.850 200.791 1.00 64.09  ? 208  ALA A O   1 
ATOM   1569  C  CB  . ALA A 1 208 ? 187.070 176.592 202.810 1.00 64.09  ? 208  ALA A CB  1 
ATOM   1570  N  N   . GLN A 1 209 ? 190.297 178.052 202.458 1.00 72.66  ? 209  GLN A N   1 
ATOM   1571  C  CA  . GLN A 1 209 ? 191.459 178.122 201.581 1.00 72.66  ? 209  GLN A CA  1 
ATOM   1572  C  C   . GLN A 1 209 ? 192.301 176.852 201.630 1.00 72.66  ? 209  GLN A C   1 
ATOM   1573  O  O   . GLN A 1 209 ? 193.498 176.891 201.328 1.00 72.66  ? 209  GLN A O   1 
ATOM   1574  C  CB  . GLN A 1 209 ? 192.317 179.338 201.926 1.00 72.66  ? 209  GLN A CB  1 
ATOM   1575  C  CG  . GLN A 1 209 ? 191.790 180.646 201.364 1.00 72.66  ? 209  GLN A CG  1 
ATOM   1576  C  CD  . GLN A 1 209 ? 192.538 181.853 201.892 1.00 72.66  ? 209  GLN A CD  1 
ATOM   1577  O  OE1 . GLN A 1 209 ? 193.231 181.775 202.906 1.00 72.66  ? 209  GLN A OE1 1 
ATOM   1578  N  NE2 . GLN A 1 209 ? 192.410 182.977 201.197 1.00 72.66  ? 209  GLN A NE2 1 
ATOM   1579  N  N   . ALA A 1 210 ? 191.695 175.721 202.002 1.00 79.67  ? 210  ALA A N   1 
ATOM   1580  C  CA  . ALA A 1 210 ? 192.441 174.468 202.058 1.00 79.67  ? 210  ALA A CA  1 
ATOM   1581  C  C   . ALA A 1 210 ? 192.957 174.058 200.685 1.00 79.67  ? 210  ALA A C   1 
ATOM   1582  O  O   . ALA A 1 210 ? 193.923 173.293 200.588 1.00 79.67  ? 210  ALA A O   1 
ATOM   1583  C  CB  . ALA A 1 210 ? 191.567 173.361 202.648 1.00 79.67  ? 210  ALA A CB  1 
ATOM   1584  N  N   . SER A 1 211 ? 192.325 174.549 199.618 1.00 80.84  ? 211  SER A N   1 
ATOM   1585  C  CA  . SER A 1 211 ? 192.784 174.228 198.272 1.00 80.84  ? 211  SER A CA  1 
ATOM   1586  C  C   . SER A 1 211 ? 194.158 174.825 197.992 1.00 80.84  ? 211  SER A C   1 
ATOM   1587  O  O   . SER A 1 211 ? 195.020 174.162 197.404 1.00 80.84  ? 211  SER A O   1 
ATOM   1588  C  CB  . SER A 1 211 ? 191.766 174.723 197.246 1.00 80.84  ? 211  SER A CB  1 
ATOM   1589  O  OG  . SER A 1 211 ? 191.690 176.137 197.246 1.00 80.84  ? 211  SER A OG  1 
ATOM   1590  N  N   . LEU A 1 212 ? 194.383 176.074 198.403 1.00 81.72  ? 212  LEU A N   1 
ATOM   1591  C  CA  . LEU A 1 212 ? 195.626 176.757 198.060 1.00 81.72  ? 212  LEU A CA  1 
ATOM   1592  C  C   . LEU A 1 212 ? 196.665 176.634 199.171 1.00 81.72  ? 212  LEU A C   1 
ATOM   1593  O  O   . LEU A 1 212 ? 197.757 176.097 198.956 1.00 81.72  ? 212  LEU A O   1 
ATOM   1594  C  CB  . LEU A 1 212 ? 195.342 178.229 197.748 1.00 81.72  ? 212  LEU A CB  1 
ATOM   1595  C  CG  . LEU A 1 212 ? 194.432 178.487 196.546 1.00 81.72  ? 212  LEU A CG  1 
ATOM   1596  C  CD1 . LEU A 1 212 ? 194.451 179.956 196.168 1.00 81.72  ? 212  LEU A CD1 1 
ATOM   1597  C  CD2 . LEU A 1 212 ? 194.842 177.622 195.364 1.00 81.72  ? 212  LEU A CD2 1 
ATOM   1598  N  N   . THR A 1 213 ? 196.342 177.125 200.367 1.00 86.70  ? 213  THR A N   1 
ATOM   1599  C  CA  . THR A 1 213 ? 197.307 177.134 201.460 1.00 86.70  ? 213  THR A CA  1 
ATOM   1600  C  C   . THR A 1 213 ? 197.410 175.795 202.180 1.00 86.70  ? 213  THR A C   1 
ATOM   1601  O  O   . THR A 1 213 ? 198.347 175.604 202.961 1.00 86.70  ? 213  THR A O   1 
ATOM   1602  C  CB  . THR A 1 213 ? 196.960 178.232 202.470 1.00 86.70  ? 213  THR A CB  1 
ATOM   1603  O  OG1 . THR A 1 213 ? 198.092 178.483 203.312 1.00 86.70  ? 213  THR A OG1 1 
ATOM   1604  C  CG2 . THR A 1 213 ? 195.782 177.813 203.335 1.00 86.70  ? 213  THR A CG2 1 
ATOM   1605  N  N   . GLY A 1 214 ? 196.481 174.872 201.941 1.00 85.00  ? 214  GLY A N   1 
ATOM   1606  C  CA  . GLY A 1 214 ? 196.546 173.564 202.558 1.00 85.00  ? 214  GLY A CA  1 
ATOM   1607  C  C   . GLY A 1 214 ? 196.052 173.493 203.984 1.00 85.00  ? 214  GLY A C   1 
ATOM   1608  O  O   . GLY A 1 214 ? 196.218 172.450 204.626 1.00 85.00  ? 214  GLY A O   1 
ATOM   1609  N  N   . GLU A 1 215 ? 195.451 174.560 204.503 1.00 89.70  ? 215  GLU A N   1 
ATOM   1610  C  CA  . GLU A 1 215 ? 194.931 174.590 205.863 1.00 89.70  ? 215  GLU A CA  1 
ATOM   1611  C  C   . GLU A 1 215 ? 193.427 174.356 205.833 1.00 89.70  ? 215  GLU A C   1 
ATOM   1612  O  O   . GLU A 1 215 ? 192.688 175.123 205.207 1.00 89.70  ? 215  GLU A O   1 
ATOM   1613  C  CB  . GLU A 1 215 ? 195.250 175.923 206.543 1.00 89.70  ? 215  GLU A CB  1 
ATOM   1614  C  CG  . GLU A 1 215 ? 196.737 176.211 206.668 1.00 89.70  ? 215  GLU A CG  1 
ATOM   1615  C  CD  . GLU A 1 215 ? 197.030 177.382 207.585 1.00 89.70  ? 215  GLU A CD  1 
ATOM   1616  O  OE1 . GLU A 1 215 ? 196.370 178.433 207.438 1.00 89.70  ? 215  GLU A OE1 1 
ATOM   1617  O  OE2 . GLU A 1 215 ? 197.920 177.253 208.451 1.00 89.70  ? 215  GLU A OE2 1 
ATOM   1618  N  N   . SER A 1 216 ? 192.980 173.302 206.518 1.00 82.76  ? 216  SER A N   1 
ATOM   1619  C  CA  . SER A 1 216 ? 191.574 172.914 206.475 1.00 82.76  ? 216  SER A CA  1 
ATOM   1620  C  C   . SER A 1 216 ? 190.665 173.934 207.148 1.00 82.76  ? 216  SER A C   1 
ATOM   1621  O  O   . SER A 1 216 ? 189.543 174.158 206.680 1.00 82.76  ? 216  SER A O   1 
ATOM   1622  C  CB  . SER A 1 216 ? 191.389 171.543 207.127 1.00 82.76  ? 216  SER A CB  1 
ATOM   1623  O  OG  . SER A 1 216 ? 192.015 170.525 206.365 1.00 82.76  ? 216  SER A OG  1 
ATOM   1624  N  N   . LEU A 1 217 ? 191.117 174.548 208.234 1.00 72.51  ? 217  LEU A N   1 
ATOM   1625  C  CA  . LEU A 1 217 ? 190.270 175.476 208.975 1.00 72.51  ? 217  LEU A CA  1 
ATOM   1626  C  C   . LEU A 1 217 ? 189.972 176.710 208.131 1.00 72.51  ? 217  LEU A C   1 
ATOM   1627  O  O   . LEU A 1 217 ? 190.872 177.231 207.462 1.00 72.51  ? 217  LEU A O   1 
ATOM   1628  C  CB  . LEU A 1 217 ? 190.941 175.889 210.283 1.00 72.51  ? 217  LEU A CB  1 
ATOM   1629  C  CG  . LEU A 1 217 ? 190.784 174.954 211.483 1.00 72.51  ? 217  LEU A CG  1 
ATOM   1630  C  CD1 . LEU A 1 217 ? 191.683 173.738 211.345 1.00 72.51  ? 217  LEU A CD1 1 
ATOM   1631  C  CD2 . LEU A 1 217 ? 191.080 175.698 212.775 1.00 72.51  ? 217  LEU A CD2 1 
ATOM   1632  N  N   . PRO A 1 218 ? 188.734 177.198 208.125 1.00 63.67  ? 218  PRO A N   1 
ATOM   1633  C  CA  . PRO A 1 218 ? 188.442 178.450 207.422 1.00 63.67  ? 218  PRO A CA  1 
ATOM   1634  C  C   . PRO A 1 218 ? 189.148 179.627 208.075 1.00 63.67  ? 218  PRO A C   1 
ATOM   1635  O  O   . PRO A 1 218 ? 189.421 179.633 209.278 1.00 63.67  ? 218  PRO A O   1 
ATOM   1636  C  CB  . PRO A 1 218 ? 186.919 178.579 207.540 1.00 63.67  ? 218  PRO A CB  1 
ATOM   1637  C  CG  . PRO A 1 218 ? 186.555 177.741 208.717 1.00 63.67  ? 218  PRO A CG  1 
ATOM   1638  C  CD  . PRO A 1 218 ? 187.530 176.605 208.727 1.00 63.67  ? 218  PRO A CD  1 
ATOM   1639  N  N   . VAL A 1 219 ? 189.449 180.631 207.258 1.00 62.85  ? 219  VAL A N   1 
ATOM   1640  C  CA  . VAL A 1 219 ? 190.131 181.835 207.710 1.00 62.85  ? 219  VAL A CA  1 
ATOM   1641  C  C   . VAL A 1 219 ? 189.199 183.024 207.530 1.00 62.85  ? 219  VAL A C   1 
ATOM   1642  O  O   . VAL A 1 219 ? 188.284 183.006 206.699 1.00 62.85  ? 219  VAL A O   1 
ATOM   1643  C  CB  . VAL A 1 219 ? 191.458 182.062 206.956 1.00 62.85  ? 219  VAL A CB  1 
ATOM   1644  C  CG1 . VAL A 1 219 ? 192.385 180.872 207.150 1.00 62.85  ? 219  VAL A CG1 1 
ATOM   1645  C  CG2 . VAL A 1 219 ? 191.195 182.305 205.479 1.00 62.85  ? 219  VAL A CG2 1 
ATOM   1646  N  N   . GLU A 1 220 ? 189.443 184.065 208.321 1.00 69.78  ? 220  GLU A N   1 
ATOM   1647  C  CA  . GLU A 1 220 ? 188.597 185.250 208.314 1.00 69.78  ? 220  GLU A CA  1 
ATOM   1648  C  C   . GLU A 1 220 ? 189.118 186.272 207.313 1.00 69.78  ? 220  GLU A C   1 
ATOM   1649  O  O   . GLU A 1 220 ? 190.316 186.570 207.280 1.00 69.78  ? 220  GLU A O   1 
ATOM   1650  C  CB  . GLU A 1 220 ? 188.537 185.864 209.712 1.00 69.78  ? 220  GLU A CB  1 
ATOM   1651  C  CG  . GLU A 1 220 ? 187.932 187.258 209.762 1.00 69.78  ? 220  GLU A CG  1 
ATOM   1652  C  CD  . GLU A 1 220 ? 186.435 187.255 209.539 1.00 69.78  ? 220  GLU A CD  1 
ATOM   1653  O  OE1 . GLU A 1 220 ? 185.794 186.221 209.819 1.00 69.78  ? 220  GLU A OE1 1 
ATOM   1654  O  OE2 . GLU A 1 220 ? 185.898 188.286 209.085 1.00 69.78  ? 220  GLU A OE2 1 
ATOM   1655  N  N   . LYS A 1 221 ? 188.215 186.805 206.496 1.00 76.65  ? 221  LYS A N   1 
ATOM   1656  C  CA  . LYS A 1 221 ? 188.527 187.874 205.556 1.00 76.65  ? 221  LYS A CA  1 
ATOM   1657  C  C   . LYS A 1 221 ? 187.773 189.126 205.983 1.00 76.65  ? 221  LYS A C   1 
ATOM   1658  O  O   . LYS A 1 221 ? 186.550 189.089 206.152 1.00 76.65  ? 221  LYS A O   1 
ATOM   1659  C  CB  . LYS A 1 221 ? 188.155 187.478 204.128 1.00 76.65  ? 221  LYS A CB  1 
ATOM   1660  C  CG  . LYS A 1 221 ? 188.943 186.304 203.578 1.00 76.65  ? 221  LYS A CG  1 
ATOM   1661  C  CD  . LYS A 1 221 ? 190.435 186.578 203.607 1.00 76.65  ? 221  LYS A CD  1 
ATOM   1662  C  CE  . LYS A 1 221 ? 191.202 185.499 202.865 1.00 76.65  ? 221  LYS A CE  1 
ATOM   1663  N  NZ  . LYS A 1 221 ? 192.607 185.383 203.342 1.00 76.65  ? 221  LYS A NZ  1 
ATOM   1664  N  N   . ALA A 1 222 ? 188.499 190.225 206.155 1.00 81.88  ? 222  ALA A N   1 
ATOM   1665  C  CA  . ALA A 1 222 ? 187.926 191.481 206.611 1.00 81.88  ? 222  ALA A CA  1 
ATOM   1666  C  C   . ALA A 1 222 ? 188.041 192.545 205.528 1.00 81.88  ? 222  ALA A C   1 
ATOM   1667  O  O   . ALA A 1 222 ? 188.801 192.408 204.566 1.00 81.88  ? 222  ALA A O   1 
ATOM   1668  C  CB  . ALA A 1 222 ? 188.612 191.964 207.894 1.00 81.88  ? 222  ALA A CB  1 
ATOM   1669  N  N   . ALA A 1 223 ? 187.257 193.613 205.696 1.00 87.79  ? 223  ALA A N   1 
ATOM   1670  C  CA  . ALA A 1 223 ? 187.309 194.728 204.755 1.00 87.79  ? 223  ALA A CA  1 
ATOM   1671  C  C   . ALA A 1 223 ? 188.676 195.397 204.765 1.00 87.79  ? 223  ALA A C   1 
ATOM   1672  O  O   . ALA A 1 223 ? 189.217 195.733 203.705 1.00 87.79  ? 223  ALA A O   1 
ATOM   1673  C  CB  . ALA A 1 223 ? 186.213 195.741 205.083 1.00 87.79  ? 223  ALA A CB  1 
ATOM   1674  N  N   . THR A 1 224 ? 189.248 195.600 205.948 1.00 87.84  ? 224  THR A N   1 
ATOM   1675  C  CA  . THR A 1 224 ? 190.569 196.191 206.102 1.00 87.84  ? 224  THR A CA  1 
ATOM   1676  C  C   . THR A 1 224 ? 191.485 195.193 206.794 1.00 87.84  ? 224  THR A C   1 
ATOM   1677  O  O   . THR A 1 224 ? 191.037 194.402 207.630 1.00 87.84  ? 224  THR A O   1 
ATOM   1678  C  CB  . THR A 1 224 ? 190.512 197.492 206.910 1.00 87.84  ? 224  THR A CB  1 
ATOM   1679  O  OG1 . THR A 1 224 ? 190.260 197.190 208.288 1.00 87.84  ? 224  THR A OG1 1 
ATOM   1680  C  CG2 . THR A 1 224 ? 189.410 198.400 206.384 1.00 87.84  ? 224  THR A CG2 1 
ATOM   1681  N  N   . THR A 1 225 ? 192.767 195.232 206.439 1.00 96.57  ? 225  THR A N   1 
ATOM   1682  C  CA  . THR A 1 225 ? 193.726 194.301 207.013 1.00 96.57  ? 225  THR A CA  1 
ATOM   1683  C  C   . THR A 1 225 ? 193.876 194.539 208.514 1.00 96.57  ? 225  THR A C   1 
ATOM   1684  O  O   . THR A 1 225 ? 193.793 195.667 209.009 1.00 96.57  ? 225  THR A O   1 
ATOM   1685  C  CB  . THR A 1 225 ? 195.083 194.428 206.318 1.00 96.57  ? 225  THR A CB  1 
ATOM   1686  O  OG1 . THR A 1 225 ? 196.027 193.548 206.943 1.00 96.57  ? 225  THR A OG1 1 
ATOM   1687  C  CG2 . THR A 1 225 ? 195.597 195.858 206.395 1.00 96.57  ? 225  THR A CG2 1 
ATOM   1688  N  N   . ARG A 1 226 ? 194.088 193.442 209.245 1.00 99.96  ? 226  ARG A N   1 
ATOM   1689  C  CA  . ARG A 1 226 ? 194.252 193.510 210.691 1.00 99.96  ? 226  ARG A CA  1 
ATOM   1690  C  C   . ARG A 1 226 ? 195.565 192.891 211.156 1.00 99.96  ? 226  ARG A C   1 
ATOM   1691  O  O   . ARG A 1 226 ? 195.732 192.665 212.361 1.00 99.96  ? 226  ARG A O   1 
ATOM   1692  C  CB  . ARG A 1 226 ? 193.079 192.820 211.398 1.00 99.96  ? 226  ARG A CB  1 
ATOM   1693  C  CG  . ARG A 1 226 ? 193.015 191.319 211.160 1.00 99.96  ? 226  ARG A CG  1 
ATOM   1694  C  CD  . ARG A 1 226 ? 191.874 190.676 211.933 1.00 99.96  ? 226  ARG A CD  1 
ATOM   1695  N  NE  . ARG A 1 226 ? 190.571 191.012 211.371 1.00 99.96  ? 226  ARG A NE  1 
ATOM   1696  C  CZ  . ARG A 1 226 ? 189.607 191.633 212.037 1.00 99.96  ? 226  ARG A CZ  1 
ATOM   1697  N  NH1 . ARG A 1 226 ? 189.764 192.000 213.298 1.00 99.96  ? 226  ARG A NH1 1 
ATOM   1698  N  NH2 . ARG A 1 226 ? 188.457 191.892 211.421 1.00 99.96  ? 226  ARG A NH2 1 
ATOM   1699  N  N   . GLN A 1 227 ? 196.497 192.615 210.247 1.00 105.56 ? 227  GLN A N   1 
ATOM   1700  C  CA  . GLN A 1 227 ? 197.749 191.956 210.571 1.00 105.56 ? 227  GLN A CA  1 
ATOM   1701  C  C   . GLN A 1 227 ? 198.907 192.725 209.950 1.00 105.56 ? 227  GLN A C   1 
ATOM   1702  O  O   . GLN A 1 227 ? 198.750 193.321 208.877 1.00 105.56 ? 227  GLN A O   1 
ATOM   1703  C  CB  . GLN A 1 227 ? 197.733 190.505 210.055 1.00 105.56 ? 227  GLN A CB  1 
ATOM   1704  C  CG  . GLN A 1 227 ? 199.007 189.709 210.290 1.00 105.56 ? 227  GLN A CG  1 
ATOM   1705  C  CD  . GLN A 1 227 ? 198.798 188.216 210.144 1.00 105.56 ? 227  GLN A CD  1 
ATOM   1706  O  OE1 . GLN A 1 227 ? 197.995 187.616 210.859 1.00 105.56 ? 227  GLN A OE1 1 
ATOM   1707  N  NE2 . GLN A 1 227 ? 199.523 187.605 209.214 1.00 105.56 ? 227  GLN A NE2 1 
ATOM   1708  N  N   . PRO A 1 228 ? 200.071 192.747 210.601 1.00 111.44 ? 228  PRO A N   1 
ATOM   1709  C  CA  . PRO A 1 228 ? 201.254 193.343 209.970 1.00 111.44 ? 228  PRO A CA  1 
ATOM   1710  C  C   . PRO A 1 228 ? 201.606 192.621 208.676 1.00 111.44 ? 228  PRO A C   1 
ATOM   1711  O  O   . PRO A 1 228 ? 201.320 191.433 208.510 1.00 111.44 ? 228  PRO A O   1 
ATOM   1712  C  CB  . PRO A 1 228 ? 202.349 193.176 211.032 1.00 111.44 ? 228  PRO A CB  1 
ATOM   1713  C  CG  . PRO A 1 228 ? 201.793 192.203 212.037 1.00 111.44 ? 228  PRO A CG  1 
ATOM   1714  C  CD  . PRO A 1 228 ? 200.317 192.407 212.010 1.00 111.44 ? 228  PRO A CD  1 
ATOM   1715  N  N   . GLU A 1 229 ? 202.219 193.360 207.752 1.00 114.40 ? 229  GLU A N   1 
ATOM   1716  C  CA  . GLU A 1 229 ? 202.471 192.854 206.408 1.00 114.40 ? 229  GLU A CA  1 
ATOM   1717  C  C   . GLU A 1 229 ? 203.288 191.569 206.438 1.00 114.40 ? 229  GLU A C   1 
ATOM   1718  O  O   . GLU A 1 229 ? 204.298 191.470 207.140 1.00 114.40 ? 229  GLU A O   1 
ATOM   1719  C  CB  . GLU A 1 229 ? 203.190 193.918 205.576 1.00 114.40 ? 229  GLU A CB  1 
ATOM   1720  C  CG  . GLU A 1 229 ? 203.270 193.599 204.087 1.00 114.40 ? 229  GLU A CG  1 
ATOM   1721  C  CD  . GLU A 1 229 ? 201.927 193.691 203.384 1.00 114.40 ? 229  GLU A CD  1 
ATOM   1722  O  OE1 . GLU A 1 229 ? 200.946 194.146 204.010 1.00 114.40 ? 229  GLU A OE1 1 
ATOM   1723  O  OE2 . GLU A 1 229 ? 201.850 193.303 202.199 1.00 114.40 ? 229  GLU A OE2 1 
ATOM   1724  N  N   . HIS A 1 230 ? 202.838 190.584 205.663 1.00 110.51 ? 230  HIS A N   1 
ATOM   1725  C  CA  . HIS A 1 230 ? 203.478 189.278 205.571 1.00 110.51 ? 230  HIS A CA  1 
ATOM   1726  C  C   . HIS A 1 230 ? 203.701 188.955 204.102 1.00 110.51 ? 230  HIS A C   1 
ATOM   1727  O  O   . HIS A 1 230 ? 202.899 189.352 203.252 1.00 110.51 ? 230  HIS A O   1 
ATOM   1728  C  CB  . HIS A 1 230 ? 202.623 188.200 206.242 1.00 110.51 ? 230  HIS A CB  1 
ATOM   1729  C  CG  . HIS A 1 230 ? 201.198 188.197 205.785 1.00 110.51 ? 230  HIS A CG  1 
ATOM   1730  N  ND1 . HIS A 1 230 ? 200.198 188.861 206.463 1.00 110.51 ? 230  HIS A ND1 1 
ATOM   1731  C  CD2 . HIS A 1 230 ? 200.606 187.620 204.713 1.00 110.51 ? 230  HIS A CD2 1 
ATOM   1732  C  CE1 . HIS A 1 230 ? 199.052 188.690 205.830 1.00 110.51 ? 230  HIS A CE1 1 
ATOM   1733  N  NE2 . HIS A 1 230 ? 199.272 187.941 204.765 1.00 110.51 ? 230  HIS A NE2 1 
ATOM   1734  N  N   . SER A 1 231 ? 204.786 188.235 203.810 1.00 111.60 ? 231  SER A N   1 
ATOM   1735  C  CA  . SER A 1 231 ? 205.169 187.980 202.424 1.00 111.60 ? 231  SER A CA  1 
ATOM   1736  C  C   . SER A 1 231 ? 204.127 187.142 201.690 1.00 111.60 ? 231  SER A C   1 
ATOM   1737  O  O   . SER A 1 231 ? 203.798 187.419 200.531 1.00 111.60 ? 231  SER A O   1 
ATOM   1738  C  CB  . SER A 1 231 ? 206.535 187.293 202.381 1.00 111.60 ? 231  SER A CB  1 
ATOM   1739  O  OG  . SER A 1 231 ? 206.516 186.076 203.107 1.00 111.60 ? 231  SER A OG  1 
ATOM   1740  N  N   . ASN A 1 232 ? 203.601 186.108 202.350 1.00 107.00 ? 232  ASN A N   1 
ATOM   1741  C  CA  . ASN A 1 232 ? 202.724 185.130 201.711 1.00 107.00 ? 232  ASN A CA  1 
ATOM   1742  C  C   . ASN A 1 232 ? 201.458 185.784 201.169 1.00 107.00 ? 232  ASN A C   1 
ATOM   1743  O  O   . ASN A 1 232 ? 200.630 186.279 201.944 1.00 107.00 ? 232  ASN A O   1 
ATOM   1744  C  CB  . ASN A 1 232 ? 202.361 184.017 202.696 1.00 107.00 ? 232  ASN A CB  1 
ATOM   1745  C  CG  . ASN A 1 232 ? 201.744 182.810 202.013 1.00 107.00 ? 232  ASN A CG  1 
ATOM   1746  O  OD1 . ASN A 1 232 ? 201.547 182.801 200.798 1.00 107.00 ? 232  ASN A OD1 1 
ATOM   1747  N  ND2 . ASN A 1 232 ? 201.441 181.780 202.794 1.00 107.00 ? 232  ASN A ND2 1 
ATOM   1748  N  N   . PRO A 1 233 ? 201.278 185.812 199.844 1.00 104.49 ? 233  PRO A N   1 
ATOM   1749  C  CA  . PRO A 1 233 ? 200.050 186.409 199.292 1.00 104.49 ? 233  PRO A CA  1 
ATOM   1750  C  C   . PRO A 1 233 ? 198.786 185.676 199.701 1.00 104.49 ? 233  PRO A C   1 
ATOM   1751  O  O   . PRO A 1 233 ? 197.739 186.311 199.878 1.00 104.49 ? 233  PRO A O   1 
ATOM   1752  C  CB  . PRO A 1 233 ? 200.282 186.344 197.774 1.00 104.49 ? 233  PRO A CB  1 
ATOM   1753  C  CG  . PRO A 1 233 ? 201.764 186.138 197.611 1.00 104.49 ? 233  PRO A CG  1 
ATOM   1754  C  CD  . PRO A 1 233 ? 202.168 185.311 198.786 1.00 104.49 ? 233  PRO A CD  1 
ATOM   1755  N  N   . LEU A 1 234 ? 198.847 184.353 199.854 1.00 99.89  ? 234  LEU A N   1 
ATOM   1756  C  CA  . LEU A 1 234 ? 197.655 183.576 200.173 1.00 99.89  ? 234  LEU A CA  1 
ATOM   1757  C  C   . LEU A 1 234 ? 197.187 183.759 201.609 1.00 99.89  ? 234  LEU A C   1 
ATOM   1758  O  O   . LEU A 1 234 ? 196.069 183.342 201.931 1.00 99.89  ? 234  LEU A O   1 
ATOM   1759  C  CB  . LEU A 1 234 ? 197.906 182.092 199.898 1.00 99.89  ? 234  LEU A CB  1 
ATOM   1760  C  CG  . LEU A 1 234 ? 198.351 181.737 198.479 1.00 99.89  ? 234  LEU A CG  1 
ATOM   1761  C  CD1 . LEU A 1 234 ? 198.421 180.229 198.297 1.00 99.89  ? 234  LEU A CD1 1 
ATOM   1762  C  CD2 . LEU A 1 234 ? 197.414 182.359 197.457 1.00 99.89  ? 234  LEU A CD2 1 
ATOM   1763  N  N   . GLU A 1 235 ? 198.000 184.363 202.475 1.00 103.49 ? 235  GLU A N   1 
ATOM   1764  C  CA  . GLU A 1 235 ? 197.603 184.605 203.855 1.00 103.49 ? 235  GLU A CA  1 
ATOM   1765  C  C   . GLU A 1 235 ? 197.002 185.984 204.076 1.00 103.49 ? 235  GLU A C   1 
ATOM   1766  O  O   . GLU A 1 235 ? 196.645 186.308 205.215 1.00 103.49 ? 235  GLU A O   1 
ATOM   1767  C  CB  . GLU A 1 235 ? 198.802 184.427 204.795 1.00 103.49 ? 235  GLU A CB  1 
ATOM   1768  C  CG  . GLU A 1 235 ? 199.252 182.986 204.960 1.00 103.49 ? 235  GLU A CG  1 
ATOM   1769  C  CD  . GLU A 1 235 ? 200.458 182.854 205.868 1.00 103.49 ? 235  GLU A CD  1 
ATOM   1770  O  OE1 . GLU A 1 235 ? 201.044 183.895 206.234 1.00 103.49 ? 235  GLU A OE1 1 
ATOM   1771  O  OE2 . GLU A 1 235 ? 200.818 181.711 206.219 1.00 103.49 ? 235  GLU A OE2 1 
ATOM   1772  N  N   . CYS A 1 236 ? 196.891 186.801 203.031 1.00 99.28  ? 236  CYS A N   1 
ATOM   1773  C  CA  . CYS A 1 236 ? 196.314 188.132 203.168 1.00 99.28  ? 236  CYS A CA  1 
ATOM   1774  C  C   . CYS A 1 236 ? 194.873 188.044 203.644 1.00 99.28  ? 236  CYS A C   1 
ATOM   1775  O  O   . CYS A 1 236 ? 194.064 187.303 203.078 1.00 99.28  ? 236  CYS A O   1 
ATOM   1776  C  CB  . CYS A 1 236 ? 196.392 188.876 201.833 1.00 99.28  ? 236  CYS A CB  1 
ATOM   1777  S  SG  . CYS A 1 236 ? 198.074 189.150 201.225 1.00 99.28  ? 236  CYS A SG  1 
ATOM   1778  N  N   . ASP A 1 237 ? 194.555 188.806 204.689 1.00 91.00  ? 237  ASP A N   1 
ATOM   1779  C  CA  . ASP A 1 237 ? 193.232 188.794 205.295 1.00 91.00  ? 237  ASP A CA  1 
ATOM   1780  C  C   . ASP A 1 237 ? 192.255 189.725 204.590 1.00 91.00  ? 237  ASP A C   1 
ATOM   1781  O  O   . ASP A 1 237 ? 191.143 189.935 205.087 1.00 91.00  ? 237  ASP A O   1 
ATOM   1782  C  CB  . ASP A 1 237 ? 193.330 189.160 206.778 1.00 91.00  ? 237  ASP A CB  1 
ATOM   1783  C  CG  . ASP A 1 237 ? 194.069 188.114 207.588 1.00 91.00  ? 237  ASP A CG  1 
ATOM   1784  O  OD1 . ASP A 1 237 ? 194.043 186.929 207.196 1.00 91.00  ? 237  ASP A OD1 1 
ATOM   1785  O  OD2 . ASP A 1 237 ? 194.676 188.477 208.617 1.00 91.00  ? 237  ASP A OD2 1 
ATOM   1786  N  N   . THR A 1 238 ? 192.643 190.288 203.447 1.00 89.88  ? 238  THR A N   1 
ATOM   1787  C  CA  . THR A 1 238 ? 191.777 191.183 202.692 1.00 89.88  ? 238  THR A CA  1 
ATOM   1788  C  C   . THR A 1 238 ? 191.621 190.808 201.227 1.00 89.88  ? 238  THR A C   1 
ATOM   1789  O  O   . THR A 1 238 ? 190.783 191.413 200.547 1.00 89.88  ? 238  THR A O   1 
ATOM   1790  C  CB  . THR A 1 238 ? 192.293 192.628 202.774 1.00 89.88  ? 238  THR A CB  1 
ATOM   1791  O  OG1 . THR A 1 238 ? 191.398 193.499 202.072 1.00 89.88  ? 238  THR A OG1 1 
ATOM   1792  C  CG2 . THR A 1 238 ? 193.679 192.731 202.163 1.00 89.88  ? 238  THR A CG2 1 
ATOM   1793  N  N   . LEU A 1 239 ? 192.383 189.846 200.717 1.00 86.79  ? 239  LEU A N   1 
ATOM   1794  C  CA  . LEU A 1 239 ? 192.296 189.419 199.328 1.00 86.79  ? 239  LEU A CA  1 
ATOM   1795  C  C   . LEU A 1 239 ? 191.787 187.987 199.258 1.00 86.79  ? 239  LEU A C   1 
ATOM   1796  O  O   . LEU A 1 239 ? 192.268 187.117 199.992 1.00 86.79  ? 239  LEU A O   1 
ATOM   1797  C  CB  . LEU A 1 239 ? 193.654 189.520 198.631 1.00 86.79  ? 239  LEU A CB  1 
ATOM   1798  C  CG  . LEU A 1 239 ? 194.232 190.913 198.391 1.00 86.79  ? 239  LEU A CG  1 
ATOM   1799  C  CD1 . LEU A 1 239 ? 195.576 190.797 197.698 1.00 86.79  ? 239  LEU A CD1 1 
ATOM   1800  C  CD2 . LEU A 1 239 ? 193.277 191.761 197.571 1.00 86.79  ? 239  LEU A CD2 1 
ATOM   1801  N  N   . CYS A 1 240 ? 190.817 187.749 198.381 1.00 83.21  ? 240  CYS A N   1 
ATOM   1802  C  CA  . CYS A 1 240 ? 190.360 186.403 198.089 1.00 83.21  ? 240  CYS A CA  1 
ATOM   1803  C  C   . CYS A 1 240 ? 191.132 185.853 196.891 1.00 83.21  ? 240  CYS A C   1 
ATOM   1804  O  O   . CYS A 1 240 ? 191.893 186.564 196.230 1.00 83.21  ? 240  CYS A O   1 
ATOM   1805  C  CB  . CYS A 1 240 ? 188.854 186.394 197.837 1.00 83.21  ? 240  CYS A CB  1 
ATOM   1806  S  SG  . CYS A 1 240 ? 187.859 186.850 199.274 1.00 83.21  ? 240  CYS A SG  1 
ATOM   1807  N  N   . PHE A 1 241 ? 190.938 184.569 196.602 1.00 80.63  ? 241  PHE A N   1 
ATOM   1808  C  CA  . PHE A 1 241 ? 191.642 183.919 195.508 1.00 80.63  ? 241  PHE A CA  1 
ATOM   1809  C  C   . PHE A 1 241 ? 190.727 182.906 194.841 1.00 80.63  ? 241  PHE A C   1 
ATOM   1810  O  O   . PHE A 1 241 ? 189.914 182.259 195.506 1.00 80.63  ? 241  PHE A O   1 
ATOM   1811  C  CB  . PHE A 1 241 ? 192.920 183.231 196.001 1.00 80.63  ? 241  PHE A CB  1 
ATOM   1812  C  CG  . PHE A 1 241 ? 194.024 184.186 196.352 1.00 80.63  ? 241  PHE A CG  1 
ATOM   1813  C  CD1 . PHE A 1 241 ? 194.787 184.778 195.361 1.00 80.63  ? 241  PHE A CD1 1 
ATOM   1814  C  CD2 . PHE A 1 241 ? 194.297 184.493 197.673 1.00 80.63  ? 241  PHE A CD2 1 
ATOM   1815  C  CE1 . PHE A 1 241 ? 195.803 185.657 195.681 1.00 80.63  ? 241  PHE A CE1 1 
ATOM   1816  C  CE2 . PHE A 1 241 ? 195.312 185.371 198.000 1.00 80.63  ? 241  PHE A CE2 1 
ATOM   1817  C  CZ  . PHE A 1 241 ? 196.066 185.953 197.002 1.00 80.63  ? 241  PHE A CZ  1 
ATOM   1818  N  N   . MET A 1 242 ? 190.870 182.771 193.524 1.00 78.68  ? 242  MET A N   1 
ATOM   1819  C  CA  . MET A 1 242 ? 190.036 181.849 192.768 1.00 78.68  ? 242  MET A CA  1 
ATOM   1820  C  C   . MET A 1 242 ? 190.307 180.409 193.188 1.00 78.68  ? 242  MET A C   1 
ATOM   1821  O  O   . MET A 1 242 ? 191.447 180.017 193.450 1.00 78.68  ? 242  MET A O   1 
ATOM   1822  C  CB  . MET A 1 242 ? 190.283 182.014 191.269 1.00 78.68  ? 242  MET A CB  1 
ATOM   1823  C  CG  . MET A 1 242 ? 189.295 181.266 190.391 1.00 78.68  ? 242  MET A CG  1 
ATOM   1824  S  SD  . MET A 1 242 ? 189.634 181.464 188.632 1.00 78.68  ? 242  MET A SD  1 
ATOM   1825  C  CE  . MET A 1 242 ? 188.331 180.461 187.922 1.00 78.68  ? 242  MET A CE  1 
ATOM   1826  N  N   . GLY A 1 243 ? 189.238 179.617 193.250 1.00 74.23  ? 243  GLY A N   1 
ATOM   1827  C  CA  . GLY A 1 243 ? 189.323 178.236 193.668 1.00 74.23  ? 243  GLY A CA  1 
ATOM   1828  C  C   . GLY A 1 243 ? 188.911 177.975 195.100 1.00 74.23  ? 243  GLY A C   1 
ATOM   1829  O  O   . GLY A 1 243 ? 188.778 176.807 195.485 1.00 74.23  ? 243  GLY A O   1 
ATOM   1830  N  N   . THR A 1 244 ? 188.705 179.016 195.896 1.00 68.84  ? 244  THR A N   1 
ATOM   1831  C  CA  . THR A 1 244 ? 188.289 178.879 197.282 1.00 68.84  ? 244  THR A CA  1 
ATOM   1832  C  C   . THR A 1 244 ? 186.806 179.202 197.425 1.00 68.84  ? 244  THR A C   1 
ATOM   1833  O  O   . THR A 1 244 ? 186.206 179.869 196.579 1.00 68.84  ? 244  THR A O   1 
ATOM   1834  C  CB  . THR A 1 244 ? 189.116 179.792 198.189 1.00 68.84  ? 244  THR A CB  1 
ATOM   1835  O  OG1 . THR A 1 244 ? 189.024 181.143 197.721 1.00 68.84  ? 244  THR A OG1 1 
ATOM   1836  C  CG2 . THR A 1 244 ? 190.573 179.362 198.182 1.00 68.84  ? 244  THR A CG2 1 
ATOM   1837  N  N   . THR A 1 245 ? 186.219 178.714 198.513 1.00 62.22  ? 245  THR A N   1 
ATOM   1838  C  CA  . THR A 1 245 ? 184.802 178.889 198.790 1.00 62.22  ? 245  THR A CA  1 
ATOM   1839  C  C   . THR A 1 245 ? 184.599 179.749 200.030 1.00 62.22  ? 245  THR A C   1 
ATOM   1840  O  O   . THR A 1 245 ? 185.507 179.935 200.844 1.00 62.22  ? 245  THR A O   1 
ATOM   1841  C  CB  . THR A 1 245 ? 184.109 177.538 198.987 1.00 62.22  ? 245  THR A CB  1 
ATOM   1842  O  OG1 . THR A 1 245 ? 184.662 176.880 200.133 1.00 62.22  ? 245  THR A OG1 1 
ATOM   1843  C  CG2 . THR A 1 245 ? 184.312 176.667 197.771 1.00 62.22  ? 245  THR A CG2 1 
ATOM   1844  N  N   . VAL A 1 246 ? 183.384 180.268 200.165 1.00 58.56  ? 246  VAL A N   1 
ATOM   1845  C  CA  . VAL A 1 246 ? 182.983 181.060 201.320 1.00 58.56  ? 246  VAL A CA  1 
ATOM   1846  C  C   . VAL A 1 246 ? 182.226 180.138 202.265 1.00 58.56  ? 246  VAL A C   1 
ATOM   1847  O  O   . VAL A 1 246 ? 181.103 179.714 201.970 1.00 58.56  ? 246  VAL A O   1 
ATOM   1848  C  CB  . VAL A 1 246 ? 182.130 182.267 200.911 1.00 58.56  ? 246  VAL A CB  1 
ATOM   1849  C  CG1 . VAL A 1 246 ? 181.527 182.928 202.138 1.00 58.56  ? 246  VAL A CG1 1 
ATOM   1850  C  CG2 . VAL A 1 246 ? 182.964 183.263 200.122 1.00 58.56  ? 246  VAL A CG2 1 
ATOM   1851  N  N   . VAL A 1 247 ? 182.843 179.815 203.402 1.00 59.41  ? 247  VAL A N   1 
ATOM   1852  C  CA  . VAL A 1 247 ? 182.204 178.927 204.368 1.00 59.41  ? 247  VAL A CA  1 
ATOM   1853  C  C   . VAL A 1 247 ? 181.003 179.611 205.009 1.00 59.41  ? 247  VAL A C   1 
ATOM   1854  O  O   . VAL A 1 247 ? 179.917 179.028 205.109 1.00 59.41  ? 247  VAL A O   1 
ATOM   1855  C  CB  . VAL A 1 247 ? 183.220 178.465 205.426 1.00 59.41  ? 247  VAL A CB  1 
ATOM   1856  C  CG1 . VAL A 1 247 ? 182.506 177.828 206.605 1.00 59.41  ? 247  VAL A CG1 1 
ATOM   1857  C  CG2 . VAL A 1 247 ? 184.207 177.491 204.816 1.00 59.41  ? 247  VAL A CG2 1 
ATOM   1858  N  N   . SER A 1 248 ? 181.174 180.855 205.445 1.00 62.27  ? 248  SER A N   1 
ATOM   1859  C  CA  . SER A 1 248 ? 180.109 181.540 206.167 1.00 62.27  ? 248  SER A CA  1 
ATOM   1860  C  C   . SER A 1 248 ? 180.303 183.045 206.053 1.00 62.27  ? 248  SER A C   1 
ATOM   1861  O  O   . SER A 1 248 ? 181.378 183.529 205.696 1.00 62.27  ? 248  SER A O   1 
ATOM   1862  C  CB  . SER A 1 248 ? 180.070 181.111 207.636 1.00 62.27  ? 248  SER A CB  1 
ATOM   1863  O  OG  . SER A 1 248 ? 181.176 181.640 208.347 1.00 62.27  ? 248  SER A OG  1 
ATOM   1864  N  N   . GLY A 1 249 ? 179.245 183.779 206.387 1.00 66.17  ? 249  GLY A N   1 
ATOM   1865  C  CA  . GLY A 1 249 ? 179.288 185.226 206.371 1.00 66.17  ? 249  GLY A CA  1 
ATOM   1866  C  C   . GLY A 1 249 ? 178.976 185.806 205.010 1.00 66.17  ? 249  GLY A C   1 
ATOM   1867  O  O   . GLY A 1 249 ? 178.797 185.104 204.010 1.00 66.17  ? 249  GLY A O   1 
ATOM   1868  N  N   . THR A 1 250 ? 178.912 187.135 204.975 1.00 75.11  ? 250  THR A N   1 
ATOM   1869  C  CA  . THR A 1 250 ? 178.587 187.860 203.755 1.00 75.11  ? 250  THR A CA  1 
ATOM   1870  C  C   . THR A 1 250 ? 179.714 188.829 203.432 1.00 75.11  ? 250  THR A C   1 
ATOM   1871  O  O   . THR A 1 250 ? 180.508 189.196 204.299 1.00 75.11  ? 250  THR A O   1 
ATOM   1872  C  CB  . THR A 1 250 ? 177.260 188.622 203.882 1.00 75.11  ? 250  THR A CB  1 
ATOM   1873  O  OG1 . THR A 1 250 ? 177.336 189.538 204.981 1.00 75.11  ? 250  THR A OG1 1 
ATOM   1874  C  CG2 . THR A 1 250 ? 176.110 187.655 204.113 1.00 75.11  ? 250  THR A CG2 1 
ATOM   1875  N  N   . ALA A 1 251 ? 179.790 189.234 202.168 1.00 75.96  ? 251  ALA A N   1 
ATOM   1876  C  CA  . ALA A 1 251 ? 180.823 190.185 201.782 1.00 75.96  ? 251  ALA A CA  1 
ATOM   1877  C  C   . ALA A 1 251 ? 180.430 190.883 200.492 1.00 75.96  ? 251  ALA A C   1 
ATOM   1878  O  O   . ALA A 1 251 ? 179.572 190.414 199.743 1.00 75.96  ? 251  ALA A O   1 
ATOM   1879  C  CB  . ALA A 1 251 ? 182.183 189.500 201.616 1.00 75.96  ? 251  ALA A CB  1 
ATOM   1880  N  N   . GLN A 1 252 ? 181.079 192.018 200.246 1.00 83.22  ? 252  GLN A N   1 
ATOM   1881  C  CA  . GLN A 1 252 ? 181.038 192.689 198.953 1.00 83.22  ? 252  GLN A CA  1 
ATOM   1882  C  C   . GLN A 1 252 ? 182.469 193.048 198.588 1.00 83.22  ? 252  GLN A C   1 
ATOM   1883  O  O   . GLN A 1 252 ? 183.164 193.698 199.377 1.00 83.22  ? 252  GLN A O   1 
ATOM   1884  C  CB  . GLN A 1 252 ? 180.152 193.937 198.989 1.00 83.22  ? 252  GLN A CB  1 
ATOM   1885  C  CG  . GLN A 1 252 ? 179.486 194.257 197.661 1.00 83.22  ? 252  GLN A CG  1 
ATOM   1886  C  CD  . GLN A 1 252 ? 178.624 195.500 197.725 1.00 83.22  ? 252  GLN A CD  1 
ATOM   1887  O  OE1 . GLN A 1 252 ? 179.127 196.622 197.687 1.00 83.22  ? 252  GLN A OE1 1 
ATOM   1888  N  NE2 . GLN A 1 252 ? 177.313 195.306 197.824 1.00 83.22  ? 252  GLN A NE2 1 
ATOM   1889  N  N   . ALA A 1 253 ? 182.908 192.617 197.408 1.00 85.52  ? 253  ALA A N   1 
ATOM   1890  C  CA  . ALA A 1 253 ? 184.299 192.737 197.003 1.00 85.52  ? 253  ALA A CA  1 
ATOM   1891  C  C   . ALA A 1 253 ? 184.391 193.222 195.563 1.00 85.52  ? 253  ALA A C   1 
ATOM   1892  O  O   . ALA A 1 253 ? 183.388 193.353 194.855 1.00 85.52  ? 253  ALA A O   1 
ATOM   1893  C  CB  . ALA A 1 253 ? 185.041 191.403 197.159 1.00 85.52  ? 253  ALA A CB  1 
ATOM   1894  N  N   . MET A 1 254 ? 185.623 193.491 195.139 1.00 95.73  ? 254  MET A N   1 
ATOM   1895  C  CA  . MET A 1 254 ? 185.928 193.972 193.799 1.00 95.73  ? 254  MET A CA  1 
ATOM   1896  C  C   . MET A 1 254 ? 186.926 193.035 193.132 1.00 95.73  ? 254  MET A C   1 
ATOM   1897  O  O   . MET A 1 254 ? 187.896 192.600 193.759 1.00 95.73  ? 254  MET A O   1 
ATOM   1898  C  CB  . MET A 1 254 ? 186.499 195.393 193.841 1.00 95.73  ? 254  MET A CB  1 
ATOM   1899  C  CG  . MET A 1 254 ? 187.000 195.904 192.501 1.00 95.73  ? 254  MET A CG  1 
ATOM   1900  S  SD  . MET A 1 254 ? 187.719 197.550 192.620 1.00 95.73  ? 254  MET A SD  1 
ATOM   1901  C  CE  . MET A 1 254 ? 186.272 198.505 193.058 1.00 95.73  ? 254  MET A CE  1 
ATOM   1902  N  N   . VAL A 1 255 ? 186.688 192.734 191.859 1.00 90.60  ? 255  VAL A N   1 
ATOM   1903  C  CA  . VAL A 1 255 ? 187.582 191.872 191.094 1.00 90.60  ? 255  VAL A CA  1 
ATOM   1904  C  C   . VAL A 1 255 ? 188.840 192.659 190.745 1.00 90.60  ? 255  VAL A C   1 
ATOM   1905  O  O   . VAL A 1 255 ? 188.761 193.760 190.192 1.00 90.60  ? 255  VAL A O   1 
ATOM   1906  C  CB  . VAL A 1 255 ? 186.892 191.345 189.828 1.00 90.60  ? 255  VAL A CB  1 
ATOM   1907  C  CG1 . VAL A 1 255 ? 187.795 190.359 189.106 1.00 90.60  ? 255  VAL A CG1 1 
ATOM   1908  C  CG2 . VAL A 1 255 ? 185.561 190.699 190.178 1.00 90.60  ? 255  VAL A CG2 1 
ATOM   1909  N  N   . ILE A 1 256 ? 190.002 192.096 191.069 1.00 93.32  ? 256  ILE A N   1 
ATOM   1910  C  CA  . ILE A 1 256 ? 191.275 192.738 190.772 1.00 93.32  ? 256  ILE A CA  1 
ATOM   1911  C  C   . ILE A 1 256 ? 192.079 191.992 189.715 1.00 93.32  ? 256  ILE A C   1 
ATOM   1912  O  O   . ILE A 1 256 ? 193.017 192.577 189.150 1.00 93.32  ? 256  ILE A O   1 
ATOM   1913  C  CB  . ILE A 1 256 ? 192.120 192.925 192.048 1.00 93.32  ? 256  ILE A CB  1 
ATOM   1914  C  CG1 . ILE A 1 256 ? 192.655 191.580 192.541 1.00 93.32  ? 256  ILE A CG1 1 
ATOM   1915  C  CG2 . ILE A 1 256 ? 191.300 193.603 193.130 1.00 93.32  ? 256  ILE A CG2 1 
ATOM   1916  C  CD1 . ILE A 1 256 ? 193.618 191.695 193.701 1.00 93.32  ? 256  ILE A CD1 1 
ATOM   1917  N  N   . ALA A 1 257 ? 191.755 190.734 189.432 1.00 92.66  ? 257  ALA A N   1 
ATOM   1918  C  CA  . ALA A 1 257 ? 192.424 189.981 188.381 1.00 92.66  ? 257  ALA A CA  1 
ATOM   1919  C  C   . ALA A 1 257 ? 191.429 188.983 187.813 1.00 92.66  ? 257  ALA A C   1 
ATOM   1920  O  O   . ALA A 1 257 ? 190.459 188.605 188.474 1.00 92.66  ? 257  ALA A O   1 
ATOM   1921  C  CB  . ALA A 1 257 ? 193.677 189.269 188.901 1.00 92.66  ? 257  ALA A CB  1 
ATOM   1922  N  N   . THR A 1 258 ? 191.679 188.559 186.577 1.00 91.90  ? 258  THR A N   1 
ATOM   1923  C  CA  . THR A 1 258 ? 190.744 187.684 185.887 1.00 91.90  ? 258  THR A CA  1 
ATOM   1924  C  C   . THR A 1 258 ? 191.498 186.847 184.864 1.00 91.90  ? 258  THR A C   1 
ATOM   1925  O  O   . THR A 1 258 ? 192.618 187.175 184.463 1.00 91.90  ? 258  THR A O   1 
ATOM   1926  C  CB  . THR A 1 258 ? 189.626 188.486 185.215 1.00 91.90  ? 258  THR A CB  1 
ATOM   1927  O  OG1 . THR A 1 258 ? 188.519 187.623 184.939 1.00 91.90  ? 258  THR A OG1 1 
ATOM   1928  C  CG2 . THR A 1 258 ? 190.116 189.096 183.912 1.00 91.90  ? 258  THR A CG2 1 
ATOM   1929  N  N   . GLY A 1 259 ? 190.862 185.755 184.446 1.00 92.13  ? 259  GLY A N   1 
ATOM   1930  C  CA  . GLY A 1 259 ? 191.449 184.883 183.443 1.00 92.13  ? 259  GLY A CA  1 
ATOM   1931  C  C   . GLY A 1 259 ? 192.781 184.321 183.892 1.00 92.13  ? 259  GLY A C   1 
ATOM   1932  O  O   . GLY A 1 259 ? 192.948 183.879 185.034 1.00 92.13  ? 259  GLY A O   1 
ATOM   1933  N  N   . ALA A 1 260 ? 193.751 184.338 182.978 1.00 96.67  ? 260  ALA A N   1 
ATOM   1934  C  CA  . ALA A 1 260 ? 195.095 183.866 183.283 1.00 96.67  ? 260  ALA A CA  1 
ATOM   1935  C  C   . ALA A 1 260 ? 195.852 184.797 184.220 1.00 96.67  ? 260  ALA A C   1 
ATOM   1936  O  O   . ALA A 1 260 ? 196.841 184.368 184.825 1.00 96.67  ? 260  ALA A O   1 
ATOM   1937  C  CB  . ALA A 1 260 ? 195.893 183.678 181.991 1.00 96.67  ? 260  ALA A CB  1 
ATOM   1938  N  N   . ASN A 1 261 ? 195.421 186.053 184.350 1.00 95.61  ? 261  ASN A N   1 
ATOM   1939  C  CA  . ASN A 1 261 ? 196.080 186.979 185.264 1.00 95.61  ? 261  ASN A CA  1 
ATOM   1940  C  C   . ASN A 1 261 ? 195.829 186.621 186.723 1.00 95.61  ? 261  ASN A C   1 
ATOM   1941  O  O   . ASN A 1 261 ? 196.528 187.130 187.605 1.00 95.61  ? 261  ASN A O   1 
ATOM   1942  C  CB  . ASN A 1 261 ? 195.611 188.408 184.986 1.00 95.61  ? 261  ASN A CB  1 
ATOM   1943  C  CG  . ASN A 1 261 ? 196.020 188.896 183.611 1.00 95.61  ? 261  ASN A CG  1 
ATOM   1944  O  OD1 . ASN A 1 261 ? 197.141 188.653 183.161 1.00 95.61  ? 261  ASN A OD1 1 
ATOM   1945  N  ND2 . ASN A 1 261 ? 195.110 189.583 182.932 1.00 95.61  ? 261  ASN A ND2 1 
ATOM   1946  N  N   . THR A 1 262 ? 194.849 185.763 186.992 1.00 94.84  ? 262  THR A N   1 
ATOM   1947  C  CA  . THR A 1 262 ? 194.557 185.338 188.353 1.00 94.84  ? 262  THR A CA  1 
ATOM   1948  C  C   . THR A 1 262 ? 195.711 184.497 188.893 1.00 94.84  ? 262  THR A C   1 
ATOM   1949  O  O   . THR A 1 262 ? 196.512 183.956 188.126 1.00 94.84  ? 262  THR A O   1 
ATOM   1950  C  CB  . THR A 1 262 ? 193.249 184.543 188.376 1.00 94.84  ? 262  THR A CB  1 
ATOM   1951  O  OG1 . THR A 1 262 ? 192.233 185.288 187.693 1.00 94.84  ? 262  THR A OG1 1 
ATOM   1952  C  CG2 . THR A 1 262 ? 192.777 184.294 189.801 1.00 94.84  ? 262  THR A CG2 1 
ATOM   1953  N  N   . TRP A 1 263 ? 195.807 184.413 190.222 1.00 95.62  ? 263  TRP A N   1 
ATOM   1954  C  CA  . TRP A 1 263 ? 196.847 183.640 190.893 1.00 95.62  ? 263  TRP A CA  1 
ATOM   1955  C  C   . TRP A 1 263 ? 196.942 182.225 190.336 1.00 95.62  ? 263  TRP A C   1 
ATOM   1956  O  O   . TRP A 1 263 ? 198.040 181.749 190.030 1.00 95.62  ? 263  TRP A O   1 
ATOM   1957  C  CB  . TRP A 1 263 ? 196.588 183.602 192.402 1.00 95.62  ? 263  TRP A CB  1 
ATOM   1958  C  CG  . TRP A 1 263 ? 197.449 182.626 193.161 1.00 95.62  ? 263  TRP A CG  1 
ATOM   1959  C  CD1 . TRP A 1 263 ? 197.256 181.278 193.283 1.00 95.62  ? 263  TRP A CD1 1 
ATOM   1960  C  CD2 . TRP A 1 263 ? 198.636 182.927 193.904 1.00 95.62  ? 263  TRP A CD2 1 
ATOM   1961  N  NE1 . TRP A 1 263 ? 198.248 180.724 194.053 1.00 95.62  ? 263  TRP A NE1 1 
ATOM   1962  C  CE2 . TRP A 1 263 ? 199.109 181.715 194.446 1.00 95.62  ? 263  TRP A CE2 1 
ATOM   1963  C  CE3 . TRP A 1 263 ? 199.346 184.103 194.162 1.00 95.62  ? 263  TRP A CE3 1 
ATOM   1964  C  CZ2 . TRP A 1 263 ? 200.257 181.647 195.232 1.00 95.62  ? 263  TRP A CZ2 1 
ATOM   1965  C  CZ3 . TRP A 1 263 ? 200.486 184.033 194.941 1.00 95.62  ? 263  TRP A CZ3 1 
ATOM   1966  C  CH2 . TRP A 1 263 ? 200.930 182.814 195.467 1.00 95.62  ? 263  TRP A CH2 1 
ATOM   1967  N  N   . PHE A 1 264 ? 195.803 181.542 190.206 1.00 96.31  ? 264  PHE A N   1 
ATOM   1968  C  CA  . PHE A 1 264 ? 195.826 180.194 189.647 1.00 96.31  ? 264  PHE A CA  1 
ATOM   1969  C  C   . PHE A 1 264 ? 196.087 180.223 188.147 1.00 96.31  ? 264  PHE A C   1 
ATOM   1970  O  O   . PHE A 1 264 ? 196.553 179.233 187.573 1.00 96.31  ? 264  PHE A O   1 
ATOM   1971  C  CB  . PHE A 1 264 ? 194.516 179.466 189.936 1.00 96.31  ? 264  PHE A CB  1 
ATOM   1972  C  CG  . PHE A 1 264 ? 194.439 178.109 189.300 1.00 96.31  ? 264  PHE A CG  1 
ATOM   1973  C  CD1 . PHE A 1 264 ? 195.236 177.073 189.757 1.00 96.31  ? 264  PHE A CD1 1 
ATOM   1974  C  CD2 . PHE A 1 264 ? 193.605 177.880 188.220 1.00 96.31  ? 264  PHE A CD2 1 
ATOM   1975  C  CE1 . PHE A 1 264 ? 195.181 175.825 189.169 1.00 96.31  ? 264  PHE A CE1 1 
ATOM   1976  C  CE2 . PHE A 1 264 ? 193.545 176.635 187.629 1.00 96.31  ? 264  PHE A CE2 1 
ATOM   1977  C  CZ  . PHE A 1 264 ? 194.335 175.606 188.102 1.00 96.31  ? 264  PHE A CZ  1 
ATOM   1978  N  N   . GLY A 1 265 ? 195.783 181.345 187.496 1.00 99.95  ? 265  GLY A N   1 
ATOM   1979  C  CA  . GLY A 1 265 ? 195.984 181.466 186.065 1.00 99.95  ? 265  GLY A CA  1 
ATOM   1980  C  C   . GLY A 1 265 ? 197.418 181.186 185.669 1.00 99.95  ? 265  GLY A C   1 
ATOM   1981  O  O   . GLY A 1 265 ? 197.676 180.519 184.662 1.00 99.95  ? 265  GLY A O   1 
ATOM   1982  N  N   . GLN A 1 266 ? 198.362 181.693 186.461 1.00 106.55 ? 266  GLN A N   1 
ATOM   1983  C  CA  . GLN A 1 266 ? 199.759 181.318 186.278 1.00 106.55 ? 266  GLN A CA  1 
ATOM   1984  C  C   . GLN A 1 266 ? 199.995 179.873 186.702 1.00 106.55 ? 266  GLN A C   1 
ATOM   1985  O  O   . GLN A 1 266 ? 200.626 179.097 185.975 1.00 106.55 ? 266  GLN A O   1 
ATOM   1986  C  CB  . GLN A 1 266 ? 200.666 182.268 187.062 1.00 106.55 ? 266  GLN A CB  1 
ATOM   1987  C  CG  . GLN A 1 266 ? 200.924 183.600 186.372 1.00 106.55 ? 266  GLN A CG  1 
ATOM   1988  C  CD  . GLN A 1 266 ? 199.697 184.491 186.338 1.00 106.55 ? 266  GLN A CD  1 
ATOM   1989  O  OE1 . GLN A 1 266 ? 199.135 184.831 187.378 1.00 106.55 ? 266  GLN A OE1 1 
ATOM   1990  N  NE2 . GLN A 1 266 ? 199.274 184.871 185.138 1.00 106.55 ? 266  GLN A NE2 1 
ATOM   1991  N  N   . LEU A 1 267 ? 199.477 179.492 187.869 1.00 108.26 ? 267  LEU A N   1 
ATOM   1992  C  CA  . LEU A 1 267 ? 199.719 178.180 188.458 1.00 108.26 ? 267  LEU A CA  1 
ATOM   1993  C  C   . LEU A 1 267 ? 199.241 177.056 187.550 1.00 108.26 ? 267  LEU A C   1 
ATOM   1994  O  O   . LEU A 1 267 ? 198.044 176.933 187.270 1.00 108.26 ? 267  LEU A O   1 
ATOM   1995  C  CB  . LEU A 1 267 ? 199.020 178.088 189.817 1.00 108.26 ? 267  LEU A CB  1 
ATOM   1996  N  N   . ALA A 1 268 ? 200.194 176.255 187.066 1.00 113.95 ? 268  ALA A N   1 
ATOM   1997  C  CA  . ALA A 1 268 ? 199.945 175.076 186.240 1.00 113.95 ? 268  ALA A CA  1 
ATOM   1998  C  C   . ALA A 1 268 ? 199.390 175.447 184.869 1.00 113.95 ? 268  ALA A C   1 
ATOM   1999  O  O   . ALA A 1 268 ? 199.222 174.578 184.008 1.00 113.95 ? 268  ALA A O   1 
ATOM   2000  C  CB  . ALA A 1 268 ? 199.001 174.101 186.951 1.00 113.95 ? 268  ALA A CB  1 
ATOM   2001  N  N   . GLY A 1 269 ? 199.105 176.732 184.655 1.00 113.62 ? 269  GLY A N   1 
ATOM   2002  C  CA  . GLY A 1 269 ? 198.718 177.181 183.328 1.00 113.62 ? 269  GLY A CA  1 
ATOM   2003  C  C   . GLY A 1 269 ? 199.862 177.855 182.600 1.00 113.62 ? 269  GLY A C   1 
ATOM   2004  O  O   . GLY A 1 269 ? 200.125 177.573 181.428 1.00 113.62 ? 269  GLY A O   1 
ATOM   2005  N  N   . ARG A 1 270 ? 200.559 178.747 183.286 1.00 118.65 ? 270  ARG A N   1 
ATOM   2006  C  CA  . ARG A 1 270 ? 201.730 179.434 182.754 1.00 118.65 ? 270  ARG A CA  1 
ATOM   2007  C  C   . ARG A 1 270 ? 202.962 179.251 183.625 1.00 118.65 ? 270  ARG A C   1 
ATOM   2008  O  O   . ARG A 1 270 ? 204.081 179.276 183.106 1.00 118.65 ? 270  ARG A O   1 
ATOM   2009  C  CB  . ARG A 1 270 ? 201.430 180.932 182.581 1.00 118.65 ? 270  ARG A CB  1 
ATOM   2010  N  N   . VAL A 1 271 ? 202.786 179.075 184.937 1.00 121.87 ? 271  VAL A N   1 
ATOM   2011  C  CA  . VAL A 1 271 ? 203.927 178.827 185.815 1.00 121.87 ? 271  VAL A CA  1 
ATOM   2012  C  C   . VAL A 1 271 ? 204.590 177.503 185.460 1.00 121.87 ? 271  VAL A C   1 
ATOM   2013  O  O   . VAL A 1 271 ? 205.820 177.410 185.373 1.00 121.87 ? 271  VAL A O   1 
ATOM   2014  C  CB  . VAL A 1 271 ? 203.485 178.861 187.289 1.00 121.87 ? 271  VAL A CB  1 
ATOM   2015  N  N   . SER A 1 272 ? 203.788 176.460 185.250 1.00 122.29 ? 272  SER A N   1 
ATOM   2016  C  CA  . SER A 1 272 ? 204.286 175.162 184.814 1.00 122.29 ? 272  SER A CA  1 
ATOM   2017  C  C   . SER A 1 272 ? 204.233 175.005 183.300 1.00 122.29 ? 272  SER A C   1 
ATOM   2018  O  O   . SER A 1 272 ? 205.269 174.785 182.666 1.00 122.29 ? 272  SER A O   1 
ATOM   2019  C  CB  . SER A 1 272 ? 203.487 174.039 185.487 1.00 122.29 ? 272  SER A CB  1 
ATOM   2020  N  N   . GLU A 1 273 ? 203.043 175.126 182.713 1.00 124.92 ? 273  GLU A N   1 
ATOM   2021  C  CA  . GLU A 1 273 ? 202.848 175.047 181.265 1.00 124.92 ? 273  GLU A CA  1 
ATOM   2022  C  C   . GLU A 1 273 ? 203.457 173.768 180.694 1.00 124.92 ? 273  GLU A C   1 
ATOM   2023  O  O   . GLU A 1 273 ? 204.127 173.768 179.660 1.00 124.92 ? 273  GLU A O   1 
ATOM   2024  C  CB  . GLU A 1 273 ? 203.417 176.284 180.570 1.00 124.92 ? 273  GLU A CB  1 
ATOM   2025  N  N   . GLN A 1 274 ? 203.216 172.664 181.391 1.00 120.11 ? 274  GLN A N   1 
ATOM   2026  C  CA  . GLN A 1 274 ? 203.732 171.362 180.998 1.00 120.11 ? 274  GLN A CA  1 
ATOM   2027  C  C   . GLN A 1 274 ? 202.708 170.617 180.149 1.00 120.11 ? 274  GLN A C   1 
ATOM   2028  O  O   . GLN A 1 274 ? 201.534 170.987 180.069 1.00 120.11 ? 274  GLN A O   1 
ATOM   2029  C  CB  . GLN A 1 274 ? 204.107 170.538 182.235 1.00 120.11 ? 274  GLN A CB  1 
ATOM   2030  N  N   . GLU A 1 275 ? 203.173 169.548 179.507 1.00 105.95 ? 275  GLU A N   1 
ATOM   2031  C  CA  . GLU A 1 275 ? 202.316 168.722 178.663 1.00 105.95 ? 275  GLU A CA  1 
ATOM   2032  C  C   . GLU A 1 275 ? 201.498 167.793 179.551 1.00 105.95 ? 275  GLU A C   1 
ATOM   2033  O  O   . GLU A 1 275 ? 202.051 166.909 180.214 1.00 105.95 ? 275  GLU A O   1 
ATOM   2034  C  CB  . GLU A 1 275 ? 203.155 167.932 177.663 1.00 105.95 ? 275  GLU A CB  1 
ATOM   2035  N  N   . SER A 1 276 ? 200.183 167.992 179.567 1.00 88.66  ? 276  SER A N   1 
ATOM   2036  C  CA  . SER A 1 276 ? 199.311 167.174 180.399 1.00 88.66  ? 276  SER A CA  1 
ATOM   2037  C  C   . SER A 1 276 ? 199.203 165.766 179.828 1.00 88.66  ? 276  SER A C   1 
ATOM   2038  O  O   . SER A 1 276 ? 199.012 165.585 178.622 1.00 88.66  ? 276  SER A O   1 
ATOM   2039  C  CB  . SER A 1 276 ? 197.928 167.813 180.503 1.00 88.66  ? 276  SER A CB  1 
ATOM   2040  N  N   . GLU A 1 277 ? 199.332 164.770 180.697 1.00 72.77  ? 277  GLU A N   1 
ATOM   2041  C  CA  . GLU A 1 277 ? 199.234 163.388 180.257 1.00 72.77  ? 277  GLU A CA  1 
ATOM   2042  C  C   . GLU A 1 277 ? 197.797 163.077 179.846 1.00 72.77  ? 277  GLU A C   1 
ATOM   2043  O  O   . GLU A 1 277 ? 196.857 163.387 180.588 1.00 72.77  ? 277  GLU A O   1 
ATOM   2044  C  CB  . GLU A 1 277 ? 199.691 162.442 181.370 1.00 72.77  ? 277  GLU A CB  1 
ATOM   2045  C  CG  . GLU A 1 277 ? 200.007 161.028 180.908 1.00 72.77  ? 277  GLU A CG  1 
ATOM   2046  C  CD  . GLU A 1 277 ? 198.810 160.103 180.991 1.00 72.77  ? 277  GLU A CD  1 
ATOM   2047  O  OE1 . GLU A 1 277 ? 197.957 160.313 181.878 1.00 72.77  ? 277  GLU A OE1 1 
ATOM   2048  O  OE2 . GLU A 1 277 ? 198.722 159.166 180.169 1.00 72.77  ? 277  GLU A OE2 1 
ATOM   2049  N  N   . PRO A 1 278 ? 197.587 162.482 178.672 1.00 61.87  ? 278  PRO A N   1 
ATOM   2050  C  CA  . PRO A 1 278 ? 196.220 162.216 178.210 1.00 61.87  ? 278  PRO A CA  1 
ATOM   2051  C  C   . PRO A 1 278 ? 195.498 161.217 179.102 1.00 61.87  ? 278  PRO A C   1 
ATOM   2052  O  O   . PRO A 1 278 ? 196.099 160.327 179.708 1.00 61.87  ? 278  PRO A O   1 
ATOM   2053  C  CB  . PRO A 1 278 ? 196.423 161.652 176.797 1.00 61.87  ? 278  PRO A CB  1 
ATOM   2054  C  CG  . PRO A 1 278 ? 197.844 161.192 176.762 1.00 61.87  ? 278  PRO A CG  1 
ATOM   2055  C  CD  . PRO A 1 278 ? 198.595 162.117 177.665 1.00 61.87  ? 278  PRO A CD  1 
ATOM   2056  N  N   . ASN A 1 279 ? 194.177 161.375 179.169 1.00 52.81  ? 279  ASN A N   1 
ATOM   2057  C  CA  . ASN A 1 279 ? 193.340 160.505 179.986 1.00 52.81  ? 279  ASN A CA  1 
ATOM   2058  C  C   . ASN A 1 279 ? 193.027 159.205 179.256 1.00 52.81  ? 279  ASN A C   1 
ATOM   2059  O  O   . ASN A 1 279 ? 193.641 158.898 178.230 1.00 52.81  ? 279  ASN A O   1 
ATOM   2060  C  CB  . ASN A 1 279 ? 192.047 161.224 180.379 1.00 52.81  ? 279  ASN A CB  1 
ATOM   2061  C  CG  . ASN A 1 279 ? 191.330 161.829 179.188 1.00 52.81  ? 279  ASN A CG  1 
ATOM   2062  O  OD1 . ASN A 1 279 ? 191.711 161.610 178.039 1.00 52.81  ? 279  ASN A OD1 1 
ATOM   2063  N  ND2 . ASN A 1 279 ? 190.285 162.601 179.460 1.00 52.81  ? 279  ASN A ND2 1 
ATOM   2064  N  N   . ALA A 1 280 ? 192.078 158.432 179.784 1.00 46.68  ? 280  ALA A N   1 
ATOM   2065  C  CA  . ALA A 1 280 ? 191.734 157.125 179.211 1.00 46.68  ? 280  ALA A CA  1 
ATOM   2066  C  C   . ALA A 1 280 ? 191.181 157.264 177.795 1.00 46.68  ? 280  ALA A C   1 
ATOM   2067  O  O   . ALA A 1 280 ? 191.562 156.512 176.894 1.00 46.68  ? 280  ALA A O   1 
ATOM   2068  C  CB  . ALA A 1 280 ? 190.740 156.401 180.122 1.00 46.68  ? 280  ALA A CB  1 
ATOM   2069  N  N   . PHE A 1 281 ? 190.277 158.224 177.590 1.00 45.13  ? 281  PHE A N   1 
ATOM   2070  C  CA  . PHE A 1 281 ? 189.633 158.392 176.292 1.00 45.13  ? 281  PHE A CA  1 
ATOM   2071  C  C   . PHE A 1 281 ? 190.628 158.798 175.213 1.00 45.13  ? 281  PHE A C   1 
ATOM   2072  O  O   . PHE A 1 281 ? 190.649 158.225 174.116 1.00 45.13  ? 281  PHE A O   1 
ATOM   2073  C  CB  . PHE A 1 281 ? 188.517 159.433 176.401 1.00 45.13  ? 281  PHE A CB  1 
ATOM   2074  C  CG  . PHE A 1 281 ? 187.603 159.465 175.214 1.00 45.13  ? 281  PHE A CG  1 
ATOM   2075  C  CD1 . PHE A 1 281 ? 186.762 158.400 174.946 1.00 45.13  ? 281  PHE A CD1 1 
ATOM   2076  C  CD2 . PHE A 1 281 ? 187.584 160.556 174.366 1.00 45.13  ? 281  PHE A CD2 1 
ATOM   2077  C  CE1 . PHE A 1 281 ? 185.918 158.424 173.858 1.00 45.13  ? 281  PHE A CE1 1 
ATOM   2078  C  CE2 . PHE A 1 281 ? 186.742 160.585 173.275 1.00 45.13  ? 281  PHE A CE2 1 
ATOM   2079  C  CZ  . PHE A 1 281 ? 185.909 159.517 173.022 1.00 45.13  ? 281  PHE A CZ  1 
ATOM   2080  N  N   . GLN A 1 282 ? 191.456 159.801 175.513 1.00 51.53  ? 282  GLN A N   1 
ATOM   2081  C  CA  . GLN A 1 282 ? 192.425 160.282 174.534 1.00 51.53  ? 282  GLN A CA  1 
ATOM   2082  C  C   . GLN A 1 282 ? 193.411 159.187 174.155 1.00 51.53  ? 282  GLN A C   1 
ATOM   2083  O  O   . GLN A 1 282 ? 193.795 159.063 172.988 1.00 51.53  ? 282  GLN A O   1 
ATOM   2084  C  CB  . GLN A 1 282 ? 193.161 161.506 175.079 1.00 51.53  ? 282  GLN A CB  1 
ATOM   2085  C  CG  . GLN A 1 282 ? 192.358 162.794 175.009 1.00 51.53  ? 282  GLN A CG  1 
ATOM   2086  C  CD  . GLN A 1 282 ? 193.120 163.984 175.557 1.00 51.53  ? 282  GLN A CD  1 
ATOM   2087  O  OE1 . GLN A 1 282 ? 193.881 163.861 176.516 1.00 51.53  ? 282  GLN A OE1 1 
ATOM   2088  N  NE2 . GLN A 1 282 ? 192.923 165.146 174.945 1.00 51.53  ? 282  GLN A NE2 1 
ATOM   2089  N  N   . GLN A 1 283 ? 193.829 158.378 175.132 1.00 53.51  ? 283  GLN A N   1 
ATOM   2090  C  CA  . GLN A 1 283 ? 194.717 157.261 174.833 1.00 53.51  ? 283  GLN A CA  1 
ATOM   2091  C  C   . GLN A 1 283 ? 194.061 156.256 173.895 1.00 53.51  ? 283  GLN A C   1 
ATOM   2092  O  O   . GLN A 1 283 ? 194.704 155.782 172.952 1.00 53.51  ? 283  GLN A O   1 
ATOM   2093  C  CB  . GLN A 1 283 ? 195.150 156.573 176.128 1.00 53.51  ? 283  GLN A CB  1 
ATOM   2094  C  CG  . GLN A 1 283 ? 196.249 157.301 176.883 1.00 53.51  ? 283  GLN A CG  1 
ATOM   2095  C  CD  . GLN A 1 283 ? 196.456 156.752 178.280 1.00 53.51  ? 283  GLN A CD  1 
ATOM   2096  O  OE1 . GLN A 1 283 ? 195.761 155.829 178.706 1.00 53.51  ? 283  GLN A OE1 1 
ATOM   2097  N  NE2 . GLN A 1 283 ? 197.418 157.315 179.001 1.00 53.51  ? 283  GLN A NE2 1 
ATOM   2098  N  N   . GLY A 1 284 ? 192.789 155.926 174.127 1.00 52.86  ? 284  GLY A N   1 
ATOM   2099  C  CA  . GLY A 1 284 ? 192.107 154.995 173.242 1.00 52.86  ? 284  GLY A CA  1 
ATOM   2100  C  C   . GLY A 1 284 ? 191.940 155.544 171.839 1.00 52.86  ? 284  GLY A C   1 
ATOM   2101  O  O   . GLY A 1 284 ? 192.108 154.825 170.848 1.00 52.86  ? 284  GLY A O   1 
ATOM   2102  N  N   . ILE A 1 285 ? 191.597 156.830 171.735 1.00 49.02  ? 285  ILE A N   1 
ATOM   2103  C  CA  . ILE A 1 285 ? 191.461 157.456 170.424 1.00 49.02  ? 285  ILE A CA  1 
ATOM   2104  C  C   . ILE A 1 285 ? 192.798 157.461 169.694 1.00 49.02  ? 285  ILE A C   1 
ATOM   2105  O  O   . ILE A 1 285 ? 192.864 157.199 168.485 1.00 49.02  ? 285  ILE A O   1 
ATOM   2106  C  CB  . ILE A 1 285 ? 190.886 158.876 170.569 1.00 49.02  ? 285  ILE A CB  1 
ATOM   2107  C  CG1 . ILE A 1 285 ? 189.470 158.817 171.141 1.00 49.02  ? 285  ILE A CG1 1 
ATOM   2108  C  CG2 . ILE A 1 285 ? 190.886 159.591 169.231 1.00 49.02  ? 285  ILE A CG2 1 
ATOM   2109  C  CD1 . ILE A 1 285 ? 188.524 157.962 170.334 1.00 49.02  ? 285  ILE A CD1 1 
ATOM   2110  N  N   . SER A 1 286 ? 193.884 157.757 170.412 1.00 53.18  ? 286  SER A N   1 
ATOM   2111  C  CA  . SER A 1 286 ? 195.210 157.717 169.806 1.00 53.18  ? 286  SER A CA  1 
ATOM   2112  C  C   . SER A 1 286 ? 195.559 156.309 169.343 1.00 53.18  ? 286  SER A C   1 
ATOM   2113  O  O   . SER A 1 286 ? 196.151 156.132 168.274 1.00 53.18  ? 286  SER A O   1 
ATOM   2114  C  CB  . SER A 1 286 ? 196.254 158.233 170.795 1.00 53.18  ? 286  SER A CB  1 
ATOM   2115  O  OG  . SER A 1 286 ? 197.560 158.131 170.255 1.00 53.18  ? 286  SER A OG  1 
ATOM   2116  N  N   . ARG A 1 287 ? 195.206 155.295 170.137 1.00 54.61  ? 287  ARG A N   1 
ATOM   2117  C  CA  . ARG A 1 287 ? 195.459 153.915 169.732 1.00 54.61  ? 287  ARG A CA  1 
ATOM   2118  C  C   . ARG A 1 287 ? 194.701 153.569 168.456 1.00 54.61  ? 287  ARG A C   1 
ATOM   2119  O  O   . ARG A 1 287 ? 195.255 152.952 167.538 1.00 54.61  ? 287  ARG A O   1 
ATOM   2120  C  CB  . ARG A 1 287 ? 195.074 152.956 170.859 1.00 54.61  ? 287  ARG A CB  1 
ATOM   2121  C  CG  . ARG A 1 287 ? 195.972 153.026 172.081 1.00 54.61  ? 287  ARG A CG  1 
ATOM   2122  C  CD  . ARG A 1 287 ? 197.332 152.416 171.790 1.00 54.61  ? 287  ARG A CD  1 
ATOM   2123  N  NE  . ARG A 1 287 ? 197.233 150.998 171.467 1.00 54.61  ? 287  ARG A NE  1 
ATOM   2124  C  CZ  . ARG A 1 287 ? 197.185 150.025 172.367 1.00 54.61  ? 287  ARG A CZ  1 
ATOM   2125  N  NH1 . ARG A 1 287 ? 197.228 150.281 173.664 1.00 54.61  ? 287  ARG A NH1 1 
ATOM   2126  N  NH2 . ARG A 1 287 ? 197.091 148.765 171.955 1.00 54.61  ? 287  ARG A NH2 1 
ATOM   2127  N  N   . VAL A 1 288 ? 193.427 153.961 168.381 1.00 52.84  ? 288  VAL A N   1 
ATOM   2128  C  CA  . VAL A 1 288 ? 192.627 153.672 167.192 1.00 52.84  ? 288  VAL A CA  1 
ATOM   2129  C  C   . VAL A 1 288 ? 193.213 154.369 165.970 1.00 52.84  ? 288  VAL A C   1 
ATOM   2130  O  O   . VAL A 1 288 ? 193.349 153.767 164.893 1.00 52.84  ? 288  VAL A O   1 
ATOM   2131  C  CB  . VAL A 1 288 ? 191.160 154.078 167.426 1.00 52.84  ? 288  VAL A CB  1 
ATOM   2132  C  CG1 . VAL A 1 288 ? 190.377 154.017 166.127 1.00 52.84  ? 288  VAL A CG1 1 
ATOM   2133  C  CG2 . VAL A 1 288 ? 190.524 153.181 168.475 1.00 52.84  ? 288  VAL A CG2 1 
ATOM   2134  N  N   . SER A 1 289 ? 193.573 155.647 166.117 1.00 57.45  ? 289  SER A N   1 
ATOM   2135  C  CA  . SER A 1 289 ? 194.145 156.388 164.999 1.00 57.45  ? 289  SER A CA  1 
ATOM   2136  C  C   . SER A 1 289 ? 195.469 155.781 164.555 1.00 57.45  ? 289  SER A C   1 
ATOM   2137  O  O   . SER A 1 289 ? 195.739 155.675 163.354 1.00 57.45  ? 289  SER A O   1 
ATOM   2138  C  CB  . SER A 1 289 ? 194.329 157.855 165.381 1.00 57.45  ? 289  SER A CB  1 
ATOM   2139  O  OG  . SER A 1 289 ? 195.119 158.532 164.421 1.00 57.45  ? 289  SER A OG  1 
ATOM   2140  N  N   . MET A 1 290 ? 196.306 155.372 165.511 1.00 60.10  ? 290  MET A N   1 
ATOM   2141  C  CA  . MET A 1 290 ? 197.585 154.763 165.169 1.00 60.10  ? 290  MET A CA  1 
ATOM   2142  C  C   . MET A 1 290 ? 197.384 153.439 164.444 1.00 60.10  ? 290  MET A C   1 
ATOM   2143  O  O   . MET A 1 290 ? 198.109 153.124 163.496 1.00 60.10  ? 290  MET A O   1 
ATOM   2144  C  CB  . MET A 1 290 ? 198.424 154.568 166.432 1.00 60.10  ? 290  MET A CB  1 
ATOM   2145  C  CG  . MET A 1 290 ? 199.334 155.742 166.757 1.00 60.10  ? 290  MET A CG  1 
ATOM   2146  S  SD  . MET A 1 290 ? 200.606 156.027 165.511 1.00 60.10  ? 290  MET A SD  1 
ATOM   2147  C  CE  . MET A 1 290 ? 201.277 154.377 165.323 1.00 60.10  ? 290  MET A CE  1 
ATOM   2148  N  N   . LEU A 1 291 ? 196.405 152.644 164.882 1.00 55.96  ? 291  LEU A N   1 
ATOM   2149  C  CA  . LEU A 1 291 ? 196.126 151.377 164.213 1.00 55.96  ? 291  LEU A CA  1 
ATOM   2150  C  C   . LEU A 1 291 ? 195.672 151.605 162.776 1.00 55.96  ? 291  LEU A C   1 
ATOM   2151  O  O   . LEU A 1 291 ? 196.122 150.917 161.847 1.00 55.96  ? 291  LEU A O   1 
ATOM   2152  C  CB  . LEU A 1 291 ? 195.073 150.596 164.998 1.00 55.96  ? 291  LEU A CB  1 
ATOM   2153  C  CG  . LEU A 1 291 ? 194.700 149.212 164.467 1.00 55.96  ? 291  LEU A CG  1 
ATOM   2154  C  CD1 . LEU A 1 291 ? 195.881 148.263 164.581 1.00 55.96  ? 291  LEU A CD1 1 
ATOM   2155  C  CD2 . LEU A 1 291 ? 193.501 148.667 165.222 1.00 55.96  ? 291  LEU A CD2 1 
ATOM   2156  N  N   . LEU A 1 292 ? 194.778 152.577 162.573 1.00 55.89  ? 292  LEU A N   1 
ATOM   2157  C  CA  . LEU A 1 292 ? 194.346 152.895 161.215 1.00 55.89  ? 292  LEU A CA  1 
ATOM   2158  C  C   . LEU A 1 292 ? 195.505 153.391 160.361 1.00 55.89  ? 292  LEU A C   1 
ATOM   2159  O  O   . LEU A 1 292 ? 195.612 153.016 159.186 1.00 55.89  ? 292  LEU A O   1 
ATOM   2160  C  CB  . LEU A 1 292 ? 193.223 153.930 161.243 1.00 55.89  ? 292  LEU A CB  1 
ATOM   2161  C  CG  . LEU A 1 292 ? 191.932 153.499 161.940 1.00 55.89  ? 292  LEU A CG  1 
ATOM   2162  C  CD1 . LEU A 1 292 ? 190.901 154.612 161.896 1.00 55.89  ? 292  LEU A CD1 1 
ATOM   2163  C  CD2 . LEU A 1 292 ? 191.382 152.234 161.305 1.00 55.89  ? 292  LEU A CD2 1 
ATOM   2164  N  N   . ILE A 1 293 ? 196.382 154.220 160.931 1.00 58.97  ? 293  ILE A N   1 
ATOM   2165  C  CA  . ILE A 1 293 ? 197.540 154.712 160.190 1.00 58.97  ? 293  ILE A CA  1 
ATOM   2166  C  C   . ILE A 1 293 ? 198.459 153.559 159.807 1.00 58.97  ? 293  ILE A C   1 
ATOM   2167  O  O   . ILE A 1 293 ? 198.985 153.512 158.691 1.00 58.97  ? 293  ILE A O   1 
ATOM   2168  C  CB  . ILE A 1 293 ? 198.286 155.784 161.003 1.00 58.97  ? 293  ILE A CB  1 
ATOM   2169  C  CG1 . ILE A 1 293 ? 197.456 157.063 161.082 1.00 58.97  ? 293  ILE A CG1 1 
ATOM   2170  C  CG2 . ILE A 1 293 ? 199.645 156.076 160.392 1.00 58.97  ? 293  ILE A CG2 1 
ATOM   2171  C  CD1 . ILE A 1 293 ? 198.031 158.095 162.014 1.00 58.97  ? 293  ILE A CD1 1 
ATOM   2172  N  N   . ARG A 1 294 ? 198.678 152.623 160.729 1.00 58.52  ? 294  ARG A N   1 
ATOM   2173  C  CA  . ARG A 1 294 ? 199.511 151.461 160.444 1.00 58.52  ? 294  ARG A CA  1 
ATOM   2174  C  C   . ARG A 1 294 ? 198.936 150.669 159.280 1.00 58.52  ? 294  ARG A C   1 
ATOM   2175  O  O   . ARG A 1 294 ? 199.653 150.353 158.325 1.00 58.52  ? 294  ARG A O   1 
ATOM   2176  C  CB  . ARG A 1 294 ? 199.641 150.564 161.676 1.00 58.52  ? 294  ARG A CB  1 
ATOM   2177  C  CG  . ARG A 1 294 ? 200.458 151.154 162.813 1.00 58.52  ? 294  ARG A CG  1 
ATOM   2178  C  CD  . ARG A 1 294 ? 200.804 150.089 163.842 1.00 58.52  ? 294  ARG A CD  1 
ATOM   2179  N  NE  . ARG A 1 294 ? 201.204 150.668 165.119 1.00 58.52  ? 294  ARG A NE  1 
ATOM   2180  C  CZ  . ARG A 1 294 ? 200.622 150.396 166.279 1.00 58.52  ? 294  ARG A CZ  1 
ATOM   2181  N  NH1 . ARG A 1 294 ? 199.606 149.552 166.361 1.00 58.52  ? 294  ARG A NH1 1 
ATOM   2182  N  NH2 . ARG A 1 294 ? 201.070 150.985 167.384 1.00 58.52  ? 294  ARG A NH2 1 
ATOM   2183  N  N   . PHE A 1 295 ? 197.639 150.357 159.343 1.00 57.91  ? 295  PHE A N   1 
ATOM   2184  C  CA  . PHE A 1 295 ? 197.019 149.581 158.272 1.00 57.91  ? 295  PHE A CA  1 
ATOM   2185  C  C   . PHE A 1 295 ? 197.121 150.302 156.931 1.00 57.91  ? 295  PHE A C   1 
ATOM   2186  O  O   . PHE A 1 295 ? 197.466 149.698 155.905 1.00 57.91  ? 295  PHE A O   1 
ATOM   2187  C  CB  . PHE A 1 295 ? 195.557 149.290 158.617 1.00 57.91  ? 295  PHE A CB  1 
ATOM   2188  C  CG  . PHE A 1 295 ? 195.357 148.009 159.372 1.00 57.91  ? 295  PHE A CG  1 
ATOM   2189  C  CD1 . PHE A 1 295 ? 195.905 147.838 160.632 1.00 57.91  ? 295  PHE A CD1 1 
ATOM   2190  C  CD2 . PHE A 1 295 ? 194.624 146.972 158.821 1.00 57.91  ? 295  PHE A CD2 1 
ATOM   2191  C  CE1 . PHE A 1 295 ? 195.722 146.659 161.328 1.00 57.91  ? 295  PHE A CE1 1 
ATOM   2192  C  CE2 . PHE A 1 295 ? 194.438 145.792 159.512 1.00 57.91  ? 295  PHE A CE2 1 
ATOM   2193  C  CZ  . PHE A 1 295 ? 194.989 145.635 160.768 1.00 57.91  ? 295  PHE A CZ  1 
ATOM   2194  N  N   . MET A 1 296 ? 196.836 151.606 156.929 1.00 62.15  ? 296  MET A N   1 
ATOM   2195  C  CA  . MET A 1 296 ? 196.886 152.380 155.693 1.00 62.15  ? 296  MET A CA  1 
ATOM   2196  C  C   . MET A 1 296 ? 198.298 152.418 155.119 1.00 62.15  ? 296  MET A C   1 
ATOM   2197  O  O   . MET A 1 296 ? 198.515 152.095 153.946 1.00 62.15  ? 296  MET A O   1 
ATOM   2198  C  CB  . MET A 1 296 ? 196.367 153.793 155.955 1.00 62.15  ? 296  MET A CB  1 
ATOM   2199  C  CG  . MET A 1 296 ? 196.538 154.751 154.797 1.00 62.15  ? 296  MET A CG  1 
ATOM   2200  S  SD  . MET A 1 296 ? 196.118 156.437 155.268 1.00 62.15  ? 296  MET A SD  1 
ATOM   2201  C  CE  . MET A 1 296 ? 197.401 156.770 156.471 1.00 62.15  ? 296  MET A CE  1 
ATOM   2202  N  N   . LEU A 1 297 ? 199.275 152.804 155.934 1.00 63.10  ? 297  LEU A N   1 
ATOM   2203  C  CA  . LEU A 1 297 ? 200.665 152.912 155.506 1.00 63.10  ? 297  LEU A CA  1 
ATOM   2204  C  C   . LEU A 1 297 ? 201.284 151.580 155.183 1.00 63.10  ? 297  LEU A C   1 
ATOM   2205  O  O   . LEU A 1 297 ? 202.350 151.556 154.556 1.00 63.10  ? 297  LEU A O   1 
ATOM   2206  C  CB  . LEU A 1 297 ? 201.484 153.622 156.584 1.00 63.10  ? 297  LEU A CB  1 
ATOM   2207  C  CG  . LEU A 1 297 ? 201.230 155.123 156.736 1.00 63.10  ? 297  LEU A CG  1 
ATOM   2208  C  CD1 . LEU A 1 297 ? 202.304 155.765 157.599 1.00 63.10  ? 297  LEU A CD1 1 
ATOM   2209  C  CD2 . LEU A 1 297 ? 201.157 155.797 155.375 1.00 63.10  ? 297  LEU A CD2 1 
ATOM   2210  N  N   . VAL A 1 298 ? 200.684 150.466 155.593 1.00 63.96  ? 298  VAL A N   1 
ATOM   2211  C  CA  . VAL A 1 298 ? 201.137 149.138 155.195 1.00 63.96  ? 298  VAL A CA  1 
ATOM   2212  C  C   . VAL A 1 298 ? 200.549 148.733 153.846 1.00 63.96  ? 298  VAL A C   1 
ATOM   2213  O  O   . VAL A 1 298 ? 201.266 148.248 152.969 1.00 63.96  ? 298  VAL A O   1 
ATOM   2214  C  CB  . VAL A 1 298 ? 200.819 148.089 156.285 1.00 63.96  ? 298  VAL A CB  1 
ATOM   2215  C  CG1 . VAL A 1 298 ? 200.898 146.686 155.712 1.00 63.96  ? 298  VAL A CG1 1 
ATOM   2216  C  CG2 . VAL A 1 298 ? 201.788 148.230 157.447 1.00 63.96  ? 298  VAL A CG2 1 
ATOM   2217  N  N   . MET A 1 299 ? 199.244 148.941 153.652 1.00 67.24  ? 299  MET A N   1 
ATOM   2218  C  CA  . MET A 1 299 ? 198.602 148.343 152.483 1.00 67.24  ? 299  MET A CA  1 
ATOM   2219  C  C   . MET A 1 299 ? 198.610 149.270 151.270 1.00 67.24  ? 299  MET A C   1 
ATOM   2220  O  O   . MET A 1 299 ? 198.762 148.799 150.137 1.00 67.24  ? 299  MET A O   1 
ATOM   2221  C  CB  . MET A 1 299 ? 197.182 147.901 152.830 1.00 67.24  ? 299  MET A CB  1 
ATOM   2222  C  CG  . MET A 1 299 ? 197.165 146.569 153.557 1.00 67.24  ? 299  MET A CG  1 
ATOM   2223  S  SD  . MET A 1 299 ? 195.535 145.901 153.909 1.00 67.24  ? 299  MET A SD  1 
ATOM   2224  C  CE  . MET A 1 299 ? 196.003 144.351 154.677 1.00 67.24  ? 299  MET A CE  1 
ATOM   2225  N  N   . ALA A 1 300 ? 198.438 150.578 151.469 1.00 69.90  ? 300  ALA A N   1 
ATOM   2226  C  CA  . ALA A 1 300 ? 198.410 151.492 150.326 1.00 69.90  ? 300  ALA A CA  1 
ATOM   2227  C  C   . ALA A 1 300 ? 199.705 151.490 149.517 1.00 69.90  ? 300  ALA A C   1 
ATOM   2228  O  O   . ALA A 1 300 ? 199.627 151.455 148.275 1.00 69.90  ? 300  ALA A O   1 
ATOM   2229  C  CB  . ALA A 1 300 ? 198.051 152.903 150.806 1.00 69.90  ? 300  ALA A CB  1 
ATOM   2230  N  N   . PRO A 1 301 ? 200.903 151.543 150.120 1.00 73.56  ? 301  PRO A N   1 
ATOM   2231  C  CA  . PRO A 1 301 ? 202.124 151.478 149.294 1.00 73.56  ? 301  PRO A CA  1 
ATOM   2232  C  C   . PRO A 1 301 ? 202.237 150.206 148.470 1.00 73.56  ? 301  PRO A C   1 
ATOM   2233  O  O   . PRO A 1 301 ? 202.806 150.236 147.373 1.00 73.56  ? 301  PRO A O   1 
ATOM   2234  C  CB  . PRO A 1 301 ? 203.248 151.596 150.331 1.00 73.56  ? 301  PRO A CB  1 
ATOM   2235  C  CG  . PRO A 1 301 ? 202.637 152.316 151.466 1.00 73.56  ? 301  PRO A CG  1 
ATOM   2236  C  CD  . PRO A 1 301 ? 201.228 151.819 151.531 1.00 73.56  ? 301  PRO A CD  1 
ATOM   2237  N  N   . VAL A 1 302 ? 201.717 149.083 148.969 1.00 73.38  ? 302  VAL A N   1 
ATOM   2238  C  CA  . VAL A 1 302 ? 201.745 147.848 148.190 1.00 73.38  ? 302  VAL A CA  1 
ATOM   2239  C  C   . VAL A 1 302 ? 200.897 147.992 146.933 1.00 73.38  ? 302  VAL A C   1 
ATOM   2240  O  O   . VAL A 1 302 ? 201.303 147.578 145.838 1.00 73.38  ? 302  VAL A O   1 
ATOM   2241  C  CB  . VAL A 1 302 ? 201.285 146.660 149.053 1.00 73.38  ? 302  VAL A CB  1 
ATOM   2242  C  CG1 . VAL A 1 302 ? 201.238 145.386 148.223 1.00 73.38  ? 302  VAL A CG1 1 
ATOM   2243  C  CG2 . VAL A 1 302 ? 202.205 146.489 150.251 1.00 73.38  ? 302  VAL A CG2 1 
ATOM   2244  N  N   . VAL A 1 303 ? 199.706 148.582 147.068 1.00 73.10  ? 303  VAL A N   1 
ATOM   2245  C  CA  . VAL A 1 303 ? 198.844 148.823 145.911 1.00 73.10  ? 303  VAL A CA  1 
ATOM   2246  C  C   . VAL A 1 303 ? 199.540 149.753 144.927 1.00 73.10  ? 303  VAL A C   1 
ATOM   2247  O  O   . VAL A 1 303 ? 199.522 149.535 143.708 1.00 73.10  ? 303  VAL A O   1 
ATOM   2248  C  CB  . VAL A 1 303 ? 197.489 149.397 146.357 1.00 73.10  ? 303  VAL A CB  1 
ATOM   2249  C  CG1 . VAL A 1 303 ? 196.608 149.684 145.150 1.00 73.10  ? 303  VAL A CG1 1 
ATOM   2250  C  CG2 . VAL A 1 303 ? 196.797 148.443 147.314 1.00 73.10  ? 303  VAL A CG2 1 
ATOM   2251  N  N   . LEU A 1 304 ? 200.156 150.816 145.451 1.00 74.96  ? 304  LEU A N   1 
ATOM   2252  C  CA  . LEU A 1 304 ? 200.911 151.744 144.618 1.00 74.96  ? 304  LEU A CA  1 
ATOM   2253  C  C   . LEU A 1 304 ? 201.995 151.026 143.822 1.00 74.96  ? 304  LEU A C   1 
ATOM   2254  O  O   . LEU A 1 304 ? 202.117 151.206 142.606 1.00 74.96  ? 304  LEU A O   1 
ATOM   2255  C  CB  . LEU A 1 304 ? 201.524 152.842 145.493 1.00 74.96  ? 304  LEU A CB  1 
ATOM   2256  C  CG  . LEU A 1 304 ? 202.614 153.712 144.860 1.00 74.96  ? 304  LEU A CG  1 
ATOM   2257  C  CD1 . LEU A 1 304 ? 202.135 154.368 143.577 1.00 74.96  ? 304  LEU A CD1 1 
ATOM   2258  C  CD2 . LEU A 1 304 ? 203.099 154.761 145.849 1.00 74.96  ? 304  LEU A CD2 1 
ATOM   2259  N  N   . LEU A 1 305 ? 202.791 150.203 144.508 1.00 82.06  ? 305  LEU A N   1 
ATOM   2260  C  CA  . LEU A 1 305 ? 203.883 149.488 143.858 1.00 82.06  ? 305  LEU A CA  1 
ATOM   2261  C  C   . LEU A 1 305 ? 203.359 148.546 142.782 1.00 82.06  ? 305  LEU A C   1 
ATOM   2262  O  O   . LEU A 1 305 ? 203.888 148.501 141.666 1.00 82.06  ? 305  LEU A O   1 
ATOM   2263  C  CB  . LEU A 1 305 ? 204.691 148.719 144.905 1.00 82.06  ? 305  LEU A CB  1 
ATOM   2264  C  CG  . LEU A 1 305 ? 205.915 147.959 144.392 1.00 82.06  ? 305  LEU A CG  1 
ATOM   2265  C  CD1 . LEU A 1 305 ? 206.933 148.921 143.804 1.00 82.06  ? 305  LEU A CD1 1 
ATOM   2266  C  CD2 . LEU A 1 305 ? 206.536 147.125 145.502 1.00 82.06  ? 305  LEU A CD2 1 
ATOM   2267  N  N   . ILE A 1 306 ? 202.305 147.789 143.102 1.00 79.54  ? 306  ILE A N   1 
ATOM   2268  C  CA  . ILE A 1 306 ? 201.768 146.816 142.151 1.00 79.54  ? 306  ILE A CA  1 
ATOM   2269  C  C   . ILE A 1 306 ? 201.255 147.524 140.903 1.00 79.54  ? 306  ILE A C   1 
ATOM   2270  O  O   . ILE A 1 306 ? 201.570 147.139 139.768 1.00 79.54  ? 306  ILE A O   1 
ATOM   2271  C  CB  . ILE A 1 306 ? 200.662 145.972 142.807 1.00 79.54  ? 306  ILE A CB  1 
ATOM   2272  C  CG1 . ILE A 1 306 ? 201.265 144.979 143.801 1.00 79.54  ? 306  ILE A CG1 1 
ATOM   2273  C  CG2 . ILE A 1 306 ? 199.849 145.243 141.749 1.00 79.54  ? 306  ILE A CG2 1 
ATOM   2274  C  CD1 . ILE A 1 306 ? 200.260 144.002 144.372 1.00 79.54  ? 306  ILE A CD1 1 
ATOM   2275  N  N   . ASN A 1 307 ? 200.466 148.583 141.096 1.00 80.08  ? 307  ASN A N   1 
ATOM   2276  C  CA  . ASN A 1 307 ? 199.880 149.279 139.955 1.00 80.08  ? 307  ASN A CA  1 
ATOM   2277  C  C   . ASN A 1 307 ? 200.949 149.979 139.124 1.00 80.08  ? 307  ASN A C   1 
ATOM   2278  O  O   . ASN A 1 307 ? 200.888 149.978 137.890 1.00 80.08  ? 307  ASN A O   1 
ATOM   2279  C  CB  . ASN A 1 307 ? 198.821 150.269 140.433 1.00 80.08  ? 307  ASN A CB  1 
ATOM   2280  C  CG  . ASN A 1 307 ? 197.548 149.583 140.879 1.00 80.08  ? 307  ASN A CG  1 
ATOM   2281  O  OD1 . ASN A 1 307 ? 197.483 148.356 140.950 1.00 80.08  ? 307  ASN A OD1 1 
ATOM   2282  N  ND2 . ASN A 1 307 ? 196.525 150.372 141.176 1.00 80.08  ? 307  ASN A ND2 1 
ATOM   2283  N  N   . GLY A 1 308 ? 201.941 150.584 139.780 1.00 84.53  ? 308  GLY A N   1 
ATOM   2284  C  CA  . GLY A 1 308 ? 203.010 151.228 139.035 1.00 84.53  ? 308  GLY A CA  1 
ATOM   2285  C  C   . GLY A 1 308 ? 203.836 150.238 138.238 1.00 84.53  ? 308  GLY A C   1 
ATOM   2286  O  O   . GLY A 1 308 ? 204.228 150.508 137.101 1.00 84.53  ? 308  GLY A O   1 
ATOM   2287  N  N   . TYR A 1 309 ? 204.113 149.073 138.828 1.00 85.38  ? 309  TYR A N   1 
ATOM   2288  C  CA  . TYR A 1 309 ? 204.912 148.067 138.139 1.00 85.38  ? 309  TYR A CA  1 
ATOM   2289  C  C   . TYR A 1 309 ? 204.149 147.463 136.967 1.00 85.38  ? 309  TYR A C   1 
ATOM   2290  O  O   . TYR A 1 309 ? 204.732 147.190 135.911 1.00 85.38  ? 309  TYR A O   1 
ATOM   2291  C  CB  . TYR A 1 309 ? 205.336 146.981 139.128 1.00 85.38  ? 309  TYR A CB  1 
ATOM   2292  C  CG  . TYR A 1 309 ? 206.555 146.189 138.709 1.00 85.38  ? 309  TYR A CG  1 
ATOM   2293  C  CD1 . TYR A 1 309 ? 206.482 145.241 137.696 1.00 85.38  ? 309  TYR A CD1 1 
ATOM   2294  C  CD2 . TYR A 1 309 ? 207.779 146.387 139.333 1.00 85.38  ? 309  TYR A CD2 1 
ATOM   2295  C  CE1 . TYR A 1 309 ? 207.595 144.516 137.316 1.00 85.38  ? 309  TYR A CE1 1 
ATOM   2296  C  CE2 . TYR A 1 309 ? 208.896 145.667 138.960 1.00 85.38  ? 309  TYR A CE2 1 
ATOM   2297  C  CZ  . TYR A 1 309 ? 208.799 144.733 137.951 1.00 85.38  ? 309  TYR A CZ  1 
ATOM   2298  O  OH  . TYR A 1 309 ? 209.911 144.015 137.577 1.00 85.38  ? 309  TYR A OH  1 
ATOM   2299  N  N   . THR A 1 310 ? 202.842 147.248 137.130 1.00 85.13  ? 310  THR A N   1 
ATOM   2300  C  CA  . THR A 1 310 ? 202.067 146.556 136.107 1.00 85.13  ? 310  THR A CA  1 
ATOM   2301  C  C   . THR A 1 310 ? 201.375 147.511 135.142 1.00 85.13  ? 310  THR A C   1 
ATOM   2302  O  O   . THR A 1 310 ? 201.596 147.441 133.929 1.00 85.13  ? 310  THR A O   1 
ATOM   2303  C  CB  . THR A 1 310 ? 201.027 145.644 136.761 1.00 85.13  ? 310  THR A CB  1 
ATOM   2304  O  OG1 . THR A 1 310 ? 201.674 144.767 137.690 1.00 85.13  ? 310  THR A OG1 1 
ATOM   2305  C  CG2 . THR A 1 310 ? 200.309 144.817 135.705 1.00 85.13  ? 310  THR A CG2 1 
ATOM   2306  N  N   . LYS A 1 311 ? 200.529 148.400 135.669 1.00 84.31  ? 311  LYS A N   1 
ATOM   2307  C  CA  . LYS A 1 311 ? 199.655 149.211 134.829 1.00 84.31  ? 311  LYS A CA  1 
ATOM   2308  C  C   . LYS A 1 311 ? 200.415 150.184 133.933 1.00 84.31  ? 311  LYS A C   1 
ATOM   2309  O  O   . LYS A 1 311 ? 200.069 150.365 132.761 1.00 84.31  ? 311  LYS A O   1 
ATOM   2310  C  CB  . LYS A 1 311 ? 198.658 149.973 135.706 1.00 84.31  ? 311  LYS A CB  1 
ATOM   2311  C  CG  . LYS A 1 311 ? 197.421 149.178 136.057 1.00 84.31  ? 311  LYS A CG  1 
ATOM   2312  C  CD  . LYS A 1 311 ? 196.504 149.072 134.856 1.00 84.31  ? 311  LYS A CD  1 
ATOM   2313  C  CE  . LYS A 1 311 ? 196.144 150.447 134.316 1.00 84.31  ? 311  LYS A CE  1 
ATOM   2314  N  NZ  . LYS A 1 311 ? 195.460 150.368 132.996 1.00 84.31  ? 311  LYS A NZ  1 
ATOM   2315  N  N   . GLY A 1 312 ? 201.454 150.821 134.464 1.00 85.77  ? 312  GLY A N   1 
ATOM   2316  C  CA  . GLY A 1 312 ? 202.068 151.912 133.734 1.00 85.77  ? 312  GLY A CA  1 
ATOM   2317  C  C   . GLY A 1 312 ? 202.189 153.185 134.545 1.00 85.77  ? 312  GLY A C   1 
ATOM   2318  O  O   . GLY A 1 312 ? 203.003 153.256 135.471 1.00 85.77  ? 312  GLY A O   1 
ATOM   2319  N  N   . ASP A 1 313 ? 201.403 154.203 134.180 1.00 82.67  ? 313  ASP A N   1 
ATOM   2320  C  CA  . ASP A 1 313 ? 201.453 155.528 134.792 1.00 82.67  ? 313  ASP A CA  1 
ATOM   2321  C  C   . ASP A 1 313 ? 201.524 155.452 136.312 1.00 82.67  ? 313  ASP A C   1 
ATOM   2322  O  O   . ASP A 1 313 ? 200.624 154.912 136.964 1.00 82.67  ? 313  ASP A O   1 
ATOM   2323  C  CB  . ASP A 1 313 ? 200.231 156.349 134.367 1.00 82.67  ? 313  ASP A CB  1 
ATOM   2324  C  CG  . ASP A 1 313 ? 200.276 157.782 134.876 1.00 82.67  ? 313  ASP A CG  1 
ATOM   2325  O  OD1 . ASP A 1 313 ? 201.303 158.188 135.461 1.00 82.67  ? 313  ASP A OD1 1 
ATOM   2326  O  OD2 . ASP A 1 313 ? 199.274 158.505 134.695 1.00 82.67  ? 313  ASP A OD2 1 
ATOM   2327  N  N   . TRP A 1 314 ? 202.601 155.999 136.879 1.00 80.68  ? 314  TRP A N   1 
ATOM   2328  C  CA  . TRP A 1 314 ? 202.813 155.919 138.319 1.00 80.68  ? 314  TRP A CA  1 
ATOM   2329  C  C   . TRP A 1 314 ? 201.931 156.912 139.065 1.00 80.68  ? 314  TRP A C   1 
ATOM   2330  O  O   . TRP A 1 314 ? 201.477 156.640 140.182 1.00 80.68  ? 314  TRP A O   1 
ATOM   2331  C  CB  . TRP A 1 314 ? 204.288 156.162 138.637 1.00 80.68  ? 314  TRP A CB  1 
ATOM   2332  C  CG  . TRP A 1 314 ? 205.137 154.941 138.485 1.00 80.68  ? 314  TRP A CG  1 
ATOM   2333  C  CD1 . TRP A 1 314 ? 205.884 154.594 137.398 1.00 80.68  ? 314  TRP A CD1 1 
ATOM   2334  C  CD2 . TRP A 1 314 ? 205.338 153.910 139.456 1.00 80.68  ? 314  TRP A CD2 1 
ATOM   2335  N  NE1 . TRP A 1 314 ? 206.533 153.405 137.629 1.00 80.68  ? 314  TRP A NE1 1 
ATOM   2336  C  CE2 . TRP A 1 314 ? 206.215 152.965 138.887 1.00 80.68  ? 314  TRP A CE2 1 
ATOM   2337  C  CE3 . TRP A 1 314 ? 204.861 153.692 140.752 1.00 80.68  ? 314  TRP A CE3 1 
ATOM   2338  C  CZ2 . TRP A 1 314 ? 206.624 151.822 139.568 1.00 80.68  ? 314  TRP A CZ2 1 
ATOM   2339  C  CZ3 . TRP A 1 314 ? 205.268 152.556 141.426 1.00 80.68  ? 314  TRP A CZ3 1 
ATOM   2340  C  CH2 . TRP A 1 314 ? 206.140 151.635 140.833 1.00 80.68  ? 314  TRP A CH2 1 
ATOM   2341  N  N   . TRP A 1 315 ? 201.688 158.080 138.467 1.00 80.53  ? 315  TRP A N   1 
ATOM   2342  C  CA  . TRP A 1 315 ? 200.935 159.125 139.152 1.00 80.53  ? 315  TRP A CA  1 
ATOM   2343  C  C   . TRP A 1 315 ? 199.490 158.701 139.390 1.00 80.53  ? 315  TRP A C   1 
ATOM   2344  O  O   . TRP A 1 315 ? 198.945 158.882 140.485 1.00 80.53  ? 315  TRP A O   1 
ATOM   2345  C  CB  . TRP A 1 315 ? 200.995 160.425 138.348 1.00 80.53  ? 315  TRP A CB  1 
ATOM   2346  C  CG  . TRP A 1 315 ? 202.283 161.177 138.518 1.00 80.53  ? 315  TRP A CG  1 
ATOM   2347  C  CD1 . TRP A 1 315 ? 203.079 161.665 137.524 1.00 80.53  ? 315  TRP A CD1 1 
ATOM   2348  C  CD2 . TRP A 1 315 ? 202.924 161.530 139.753 1.00 80.53  ? 315  TRP A CD2 1 
ATOM   2349  N  NE1 . TRP A 1 315 ? 204.174 162.297 138.060 1.00 80.53  ? 315  TRP A NE1 1 
ATOM   2350  C  CE2 . TRP A 1 315 ? 204.102 162.228 139.426 1.00 80.53  ? 315  TRP A CE2 1 
ATOM   2351  C  CE3 . TRP A 1 315 ? 202.615 161.325 141.103 1.00 80.53  ? 315  TRP A CE3 1 
ATOM   2352  C  CZ2 . TRP A 1 315 ? 204.972 162.720 140.396 1.00 80.53  ? 315  TRP A CZ2 1 
ATOM   2353  C  CZ3 . TRP A 1 315 ? 203.481 161.813 142.063 1.00 80.53  ? 315  TRP A CZ3 1 
ATOM   2354  C  CH2 . TRP A 1 315 ? 204.644 162.503 141.705 1.00 80.53  ? 315  TRP A CH2 1 
ATOM   2355  N  N   . GLU A 1 316 ? 198.853 158.129 138.367 1.00 78.19  ? 316  GLU A N   1 
ATOM   2356  C  CA  . GLU A 1 316 ? 197.489 157.642 138.535 1.00 78.19  ? 316  GLU A CA  1 
ATOM   2357  C  C   . GLU A 1 316 ? 197.445 156.492 139.531 1.00 78.19  ? 316  GLU A C   1 
ATOM   2358  O  O   . GLU A 1 316 ? 196.483 156.349 140.291 1.00 78.19  ? 316  GLU A O   1 
ATOM   2359  C  CB  . GLU A 1 316 ? 196.906 157.213 137.188 1.00 78.19  ? 316  GLU A CB  1 
ATOM   2360  C  CG  . GLU A 1 316 ? 195.396 157.365 137.106 1.00 78.19  ? 316  GLU A CG  1 
ATOM   2361  C  CD  . GLU A 1 316 ? 194.896 157.487 135.682 1.00 78.19  ? 316  GLU A CD  1 
ATOM   2362  O  OE1 . GLU A 1 316 ? 195.720 157.389 134.749 1.00 78.19  ? 316  GLU A OE1 1 
ATOM   2363  O  OE2 . GLU A 1 316 ? 193.676 157.681 135.496 1.00 78.19  ? 316  GLU A OE2 1 
ATOM   2364  N  N   . ALA A 1 317 ? 198.489 155.660 139.542 1.00 77.45  ? 317  ALA A N   1 
ATOM   2365  C  CA  . ALA A 1 317 ? 198.559 154.574 140.514 1.00 77.45  ? 317  ALA A CA  1 
ATOM   2366  C  C   . ALA A 1 317 ? 198.618 155.110 141.939 1.00 77.45  ? 317  ALA A C   1 
ATOM   2367  O  O   . ALA A 1 317 ? 197.927 154.605 142.832 1.00 77.45  ? 317  ALA A O   1 
ATOM   2368  C  CB  . ALA A 1 317 ? 199.772 153.692 140.223 1.00 77.45  ? 317  ALA A CB  1 
ATOM   2369  N  N   . ALA A 1 318 ? 199.442 156.135 142.170 1.00 75.31  ? 318  ALA A N   1 
ATOM   2370  C  CA  . ALA A 1 318 ? 199.524 156.738 143.496 1.00 75.31  ? 318  ALA A CA  1 
ATOM   2371  C  C   . ALA A 1 318 ? 198.211 157.401 143.879 1.00 75.31  ? 318  ALA A C   1 
ATOM   2372  O  O   . ALA A 1 318 ? 197.775 157.314 145.032 1.00 75.31  ? 318  ALA A O   1 
ATOM   2373  C  CB  . ALA A 1 318 ? 200.671 157.747 143.546 1.00 75.31  ? 318  ALA A CB  1 
ATOM   2374  N  N   . LEU A 1 319 ? 197.568 158.071 142.922 1.00 73.51  ? 319  LEU A N   1 
ATOM   2375  C  CA  . LEU A 1 319 ? 196.271 158.682 143.186 1.00 73.51  ? 319  LEU A CA  1 
ATOM   2376  C  C   . LEU A 1 319 ? 195.242 157.629 143.578 1.00 73.51  ? 319  LEU A C   1 
ATOM   2377  O  O   . LEU A 1 319 ? 194.469 157.824 144.521 1.00 73.51  ? 319  LEU A O   1 
ATOM   2378  C  CB  . LEU A 1 319 ? 195.811 159.453 141.949 1.00 73.51  ? 319  LEU A CB  1 
ATOM   2379  C  CG  . LEU A 1 319 ? 194.604 160.388 142.010 1.00 73.51  ? 319  LEU A CG  1 
ATOM   2380  C  CD1 . LEU A 1 319 ? 194.766 161.433 140.938 1.00 73.51  ? 319  LEU A CD1 1 
ATOM   2381  C  CD2 . LEU A 1 319 ? 193.305 159.649 141.806 1.00 73.51  ? 319  LEU A CD2 1 
ATOM   2382  N  N   . PHE A 1 320 ? 195.226 156.504 142.863 1.00 73.13  ? 320  PHE A N   1 
ATOM   2383  C  CA  . PHE A 1 320 ? 194.283 155.428 143.150 1.00 73.13  ? 320  PHE A CA  1 
ATOM   2384  C  C   . PHE A 1 320 ? 194.552 154.804 144.515 1.00 73.13  ? 320  PHE A C   1 
ATOM   2385  O  O   . PHE A 1 320 ? 193.616 154.521 145.278 1.00 73.13  ? 320  PHE A O   1 
ATOM   2386  C  CB  . PHE A 1 320 ? 194.377 154.389 142.032 1.00 73.13  ? 320  PHE A CB  1 
ATOM   2387  C  CG  . PHE A 1 320 ? 193.556 153.160 142.257 1.00 73.13  ? 320  PHE A CG  1 
ATOM   2388  C  CD1 . PHE A 1 320 ? 192.177 153.204 142.176 1.00 73.13  ? 320  PHE A CD1 1 
ATOM   2389  C  CD2 . PHE A 1 320 ? 194.169 151.951 142.516 1.00 73.13  ? 320  PHE A CD2 1 
ATOM   2390  C  CE1 . PHE A 1 320 ? 191.428 152.063 142.366 1.00 73.13  ? 320  PHE A CE1 1 
ATOM   2391  C  CE2 . PHE A 1 320 ? 193.425 150.813 142.704 1.00 73.13  ? 320  PHE A CE2 1 
ATOM   2392  C  CZ  . PHE A 1 320 ? 192.051 150.868 142.633 1.00 73.13  ? 320  PHE A CZ  1 
ATOM   2393  N  N   . ALA A 1 321 ? 195.829 154.582 144.841 1.00 72.44  ? 321  ALA A N   1 
ATOM   2394  C  CA  . ALA A 1 321 ? 196.179 154.037 146.148 1.00 72.44  ? 321  ALA A CA  1 
ATOM   2395  C  C   . ALA A 1 321 ? 195.775 154.987 147.267 1.00 72.44  ? 321  ALA A C   1 
ATOM   2396  O  O   . ALA A 1 321 ? 195.235 154.558 148.292 1.00 72.44  ? 321  ALA A O   1 
ATOM   2397  C  CB  . ALA A 1 321 ? 197.676 153.739 146.209 1.00 72.44  ? 321  ALA A CB  1 
ATOM   2398  N  N   . LEU A 1 322 ? 196.019 156.285 147.086 1.00 71.30  ? 322  LEU A N   1 
ATOM   2399  C  CA  . LEU A 1 322 ? 195.601 157.252 148.093 1.00 71.30  ? 322  LEU A CA  1 
ATOM   2400  C  C   . LEU A 1 322 ? 194.084 157.290 148.217 1.00 71.30  ? 322  LEU A C   1 
ATOM   2401  O  O   . LEU A 1 322 ? 193.548 157.414 149.322 1.00 71.30  ? 322  LEU A O   1 
ATOM   2402  C  CB  . LEU A 1 322 ? 196.147 158.637 147.755 1.00 71.30  ? 322  LEU A CB  1 
ATOM   2403  C  CG  . LEU A 1 322 ? 196.020 159.671 148.873 1.00 71.30  ? 322  LEU A CG  1 
ATOM   2404  C  CD1 . LEU A 1 322 ? 196.681 159.164 150.143 1.00 71.30  ? 322  LEU A CD1 1 
ATOM   2405  C  CD2 . LEU A 1 322 ? 196.618 160.997 148.446 1.00 71.30  ? 322  LEU A CD2 1 
ATOM   2406  N  N   . SER A 1 323 ? 193.375 157.178 147.092 1.00 70.23  ? 323  SER A N   1 
ATOM   2407  C  CA  . SER A 1 323 ? 191.918 157.207 147.128 1.00 70.23  ? 323  SER A CA  1 
ATOM   2408  C  C   . SER A 1 323 ? 191.358 156.018 147.897 1.00 70.23  ? 323  SER A C   1 
ATOM   2409  O  O   . SER A 1 323 ? 190.428 156.174 148.697 1.00 70.23  ? 323  SER A O   1 
ATOM   2410  C  CB  . SER A 1 323 ? 191.359 157.238 145.708 1.00 70.23  ? 323  SER A CB  1 
ATOM   2411  O  OG  . SER A 1 323 ? 189.951 157.083 145.714 1.00 70.23  ? 323  SER A OG  1 
ATOM   2412  N  N   . VAL A 1 324 ? 191.903 154.820 147.671 1.00 69.56  ? 324  VAL A N   1 
ATOM   2413  C  CA  . VAL A 1 324 ? 191.415 153.674 148.435 1.00 69.56  ? 324  VAL A CA  1 
ATOM   2414  C  C   . VAL A 1 324 ? 191.848 153.774 149.894 1.00 69.56  ? 324  VAL A C   1 
ATOM   2415  O  O   . VAL A 1 324 ? 191.127 153.322 150.792 1.00 69.56  ? 324  VAL A O   1 
ATOM   2416  C  CB  . VAL A 1 324 ? 191.852 152.338 147.802 1.00 69.56  ? 324  VAL A CB  1 
ATOM   2417  C  CG1 . VAL A 1 324 ? 191.175 152.141 146.457 1.00 69.56  ? 324  VAL A CG1 1 
ATOM   2418  C  CG2 . VAL A 1 324 ? 193.356 152.254 147.666 1.00 69.56  ? 324  VAL A CG2 1 
ATOM   2419  N  N   . ALA A 1 325 ? 193.015 154.369 150.164 1.00 68.40  ? 325  ALA A N   1 
ATOM   2420  C  CA  . ALA A 1 325 ? 193.470 154.504 151.545 1.00 68.40  ? 325  ALA A CA  1 
ATOM   2421  C  C   . ALA A 1 325 ? 192.662 155.551 152.303 1.00 68.40  ? 325  ALA A C   1 
ATOM   2422  O  O   . ALA A 1 325 ? 192.625 155.536 153.539 1.00 68.40  ? 325  ALA A O   1 
ATOM   2423  C  CB  . ALA A 1 325 ? 194.957 154.852 151.571 1.00 68.40  ? 325  ALA A CB  1 
ATOM   2424  N  N   . VAL A 1 326 ? 192.023 156.472 151.582 1.00 64.50  ? 326  VAL A N   1 
ATOM   2425  C  CA  . VAL A 1 326 ? 191.192 157.508 152.190 1.00 64.50  ? 326  VAL A CA  1 
ATOM   2426  C  C   . VAL A 1 326 ? 190.068 156.861 152.989 1.00 64.50  ? 326  VAL A C   1 
ATOM   2427  O  O   . VAL A 1 326 ? 189.615 157.408 154.001 1.00 64.50  ? 326  VAL A O   1 
ATOM   2428  C  CB  . VAL A 1 326 ? 190.647 158.473 151.120 1.00 64.50  ? 326  VAL A CB  1 
ATOM   2429  C  CG1 . VAL A 1 326 ? 189.410 159.207 151.612 1.00 64.50  ? 326  VAL A CG1 1 
ATOM   2430  C  CG2 . VAL A 1 326 ? 191.713 159.479 150.743 1.00 64.50  ? 326  VAL A CG2 1 
ATOM   2431  N  N   . GLY A 1 327 ? 189.630 155.678 152.557 1.00 65.58  ? 327  GLY A N   1 
ATOM   2432  C  CA  . GLY A 1 327 ? 188.607 154.968 153.306 1.00 65.58  ? 327  GLY A CA  1 
ATOM   2433  C  C   . GLY A 1 327 ? 189.012 154.707 154.744 1.00 65.58  ? 327  GLY A C   1 
ATOM   2434  O  O   . GLY A 1 327 ? 188.192 154.816 155.659 1.00 65.58  ? 327  GLY A O   1 
ATOM   2435  N  N   . LEU A 1 328 ? 190.282 154.371 154.966 1.00 65.24  ? 328  LEU A N   1 
ATOM   2436  C  CA  . LEU A 1 328 ? 190.802 154.121 156.305 1.00 65.24  ? 328  LEU A CA  1 
ATOM   2437  C  C   . LEU A 1 328 ? 191.514 155.332 156.894 1.00 65.24  ? 328  LEU A C   1 
ATOM   2438  O  O   . LEU A 1 328 ? 192.490 155.168 157.639 1.00 65.24  ? 328  LEU A O   1 
ATOM   2439  C  CB  . LEU A 1 328 ? 191.738 152.912 156.285 1.00 65.24  ? 328  LEU A CB  1 
ATOM   2440  C  CG  . LEU A 1 328 ? 191.079 151.551 156.060 1.00 65.24  ? 328  LEU A CG  1 
ATOM   2441  C  CD1 . LEU A 1 328 ? 192.122 150.446 156.051 1.00 65.24  ? 328  LEU A CD1 1 
ATOM   2442  C  CD2 . LEU A 1 328 ? 190.030 151.292 157.127 1.00 65.24  ? 328  LEU A CD2 1 
ATOM   2443  N  N   . THR A 1 329 ? 191.063 156.540 156.577 1.00 66.55  ? 329  THR A N   1 
ATOM   2444  C  CA  . THR A 1 329 ? 191.723 157.728 157.096 1.00 66.55  ? 329  THR A CA  1 
ATOM   2445  C  C   . THR A 1 329 ? 191.521 157.822 158.607 1.00 66.55  ? 329  THR A C   1 
ATOM   2446  O  O   . THR A 1 329 ? 190.467 157.429 159.121 1.00 66.55  ? 329  THR A O   1 
ATOM   2447  C  CB  . THR A 1 329 ? 191.191 158.992 156.414 1.00 66.55  ? 329  THR A CB  1 
ATOM   2448  O  OG1 . THR A 1 329 ? 191.892 160.137 156.915 1.00 66.55  ? 329  THR A OG1 1 
ATOM   2449  C  CG2 . THR A 1 329 ? 189.699 159.165 156.670 1.00 66.55  ? 329  THR A CG2 1 
ATOM   2450  N  N   . PRO A 1 330 ? 192.515 158.311 159.350 1.00 61.24  ? 330  PRO A N   1 
ATOM   2451  C  CA  . PRO A 1 330 ? 192.356 158.471 160.799 1.00 61.24  ? 330  PRO A CA  1 
ATOM   2452  C  C   . PRO A 1 330 ? 191.699 159.775 161.220 1.00 61.24  ? 330  PRO A C   1 
ATOM   2453  O  O   . PRO A 1 330 ? 191.393 159.933 162.407 1.00 61.24  ? 330  PRO A O   1 
ATOM   2454  C  CB  . PRO A 1 330 ? 193.804 158.406 161.300 1.00 61.24  ? 330  PRO A CB  1 
ATOM   2455  C  CG  . PRO A 1 330 ? 194.582 159.010 160.186 1.00 61.24  ? 330  PRO A CG  1 
ATOM   2456  C  CD  . PRO A 1 330 ? 193.906 158.540 158.922 1.00 61.24  ? 330  PRO A CD  1 
ATOM   2457  N  N   . GLU A 1 331 ? 191.466 160.710 160.298 1.00 64.29  ? 331  GLU A N   1 
ATOM   2458  C  CA  . GLU A 1 331 ? 190.888 162.001 160.643 1.00 64.29  ? 331  GLU A CA  1 
ATOM   2459  C  C   . GLU A 1 331 ? 189.364 161.980 160.621 1.00 64.29  ? 331  GLU A C   1 
ATOM   2460  O  O   . GLU A 1 331 ? 188.730 163.020 160.825 1.00 64.29  ? 331  GLU A O   1 
ATOM   2461  C  CB  . GLU A 1 331 ? 191.418 163.095 159.715 1.00 64.29  ? 331  GLU A CB  1 
ATOM   2462  C  CG  . GLU A 1 331 ? 191.418 164.470 160.368 1.00 64.29  ? 331  GLU A CG  1 
ATOM   2463  C  CD  . GLU A 1 331 ? 192.409 165.425 159.748 1.00 64.29  ? 331  GLU A CD  1 
ATOM   2464  O  OE1 . GLU A 1 331 ? 193.604 165.072 159.657 1.00 64.29  ? 331  GLU A OE1 1 
ATOM   2465  O  OE2 . GLU A 1 331 ? 191.992 166.538 159.363 1.00 64.29  ? 331  GLU A OE2 1 
ATOM   2466  N  N   . MET A 1 332 ? 188.764 160.822 160.371 1.00 58.34  ? 332  MET A N   1 
ATOM   2467  C  CA  . MET A 1 332 ? 187.336 160.668 160.596 1.00 58.34  ? 332  MET A CA  1 
ATOM   2468  C  C   . MET A 1 332 ? 186.992 160.585 162.076 1.00 58.34  ? 332  MET A C   1 
ATOM   2469  O  O   . MET A 1 332 ? 185.875 160.948 162.460 1.00 58.34  ? 332  MET A O   1 
ATOM   2470  C  CB  . MET A 1 332 ? 186.818 159.425 159.865 1.00 58.34  ? 332  MET A CB  1 
ATOM   2471  C  CG  . MET A 1 332 ? 187.363 158.115 160.406 1.00 58.34  ? 332  MET A CG  1 
ATOM   2472  S  SD  . MET A 1 332 ? 186.814 156.681 159.464 1.00 58.34  ? 332  MET A SD  1 
ATOM   2473  C  CE  . MET A 1 332 ? 187.567 155.357 160.404 1.00 58.34  ? 332  MET A CE  1 
ATOM   2474  N  N   . LEU A 1 333 ? 187.934 160.139 162.910 1.00 48.98  ? 333  LEU A N   1 
ATOM   2475  C  CA  . LEU A 1 333 ? 187.684 160.027 164.347 1.00 48.98  ? 333  LEU A CA  1 
ATOM   2476  C  C   . LEU A 1 333 ? 187.299 161.349 165.001 1.00 48.98  ? 333  LEU A C   1 
ATOM   2477  O  O   . LEU A 1 333 ? 186.378 161.346 165.837 1.00 48.98  ? 333  LEU A O   1 
ATOM   2478  C  CB  . LEU A 1 333 ? 188.904 159.403 165.035 1.00 48.98  ? 333  LEU A CB  1 
ATOM   2479  C  CG  . LEU A 1 333 ? 188.967 157.876 165.125 1.00 48.98  ? 333  LEU A CG  1 
ATOM   2480  C  CD1 . LEU A 1 333 ? 187.767 157.344 165.889 1.00 48.98  ? 333  LEU A CD1 1 
ATOM   2481  C  CD2 . LEU A 1 333 ? 189.062 157.232 163.752 1.00 48.98  ? 333  LEU A CD2 1 
ATOM   2482  N  N   . PRO A 1 334 ? 187.952 162.497 164.707 1.00 50.34  ? 334  PRO A N   1 
ATOM   2483  C  CA  . PRO A 1 334 ? 187.516 163.758 165.326 1.00 50.34  ? 334  PRO A CA  1 
ATOM   2484  C  C   . PRO A 1 334 ? 186.050 164.073 165.075 1.00 50.34  ? 334  PRO A C   1 
ATOM   2485  O  O   . PRO A 1 334 ? 185.384 164.655 165.935 1.00 50.34  ? 334  PRO A O   1 
ATOM   2486  C  CB  . PRO A 1 334 ? 188.432 164.798 164.673 1.00 50.34  ? 334  PRO A CB  1 
ATOM   2487  C  CG  . PRO A 1 334 ? 189.675 164.049 164.402 1.00 50.34  ? 334  PRO A CG  1 
ATOM   2488  C  CD  . PRO A 1 334 ? 189.230 162.672 163.990 1.00 50.34  ? 334  PRO A CD  1 
ATOM   2489  N  N   . MET A 1 335 ? 185.536 163.701 163.902 1.00 54.15  ? 335  MET A N   1 
ATOM   2490  C  CA  . MET A 1 335 ? 184.109 163.871 163.650 1.00 54.15  ? 335  MET A CA  1 
ATOM   2491  C  C   . MET A 1 335 ? 183.295 162.826 164.403 1.00 54.15  ? 335  MET A C   1 
ATOM   2492  O  O   . MET A 1 335 ? 182.418 163.170 165.204 1.00 54.15  ? 335  MET A O   1 
ATOM   2493  C  CB  . MET A 1 335 ? 183.818 163.797 162.151 1.00 54.15  ? 335  MET A CB  1 
ATOM   2494  C  CG  . MET A 1 335 ? 182.364 163.470 161.833 1.00 54.15  ? 335  MET A CG  1 
ATOM   2495  S  SD  . MET A 1 335 ? 182.017 163.347 160.069 1.00 54.15  ? 335  MET A SD  1 
ATOM   2496  C  CE  . MET A 1 335 ? 182.488 161.650 159.745 1.00 54.15  ? 335  MET A CE  1 
ATOM   2497  N  N   . ILE A 1 336 ? 183.604 161.544 164.183 1.00 45.62  ? 336  ILE A N   1 
ATOM   2498  C  CA  . ILE A 1 336 ? 182.809 160.418 164.666 1.00 45.62  ? 336  ILE A CA  1 
ATOM   2499  C  C   . ILE A 1 336 ? 182.486 160.589 166.141 1.00 45.62  ? 336  ILE A C   1 
ATOM   2500  O  O   . ILE A 1 336 ? 181.315 160.729 166.517 1.00 45.62  ? 336  ILE A O   1 
ATOM   2501  C  CB  . ILE A 1 336 ? 183.547 159.087 164.437 1.00 45.62  ? 336  ILE A CB  1 
ATOM   2502  C  CG1 . ILE A 1 336 ? 183.724 158.818 162.944 1.00 45.62  ? 336  ILE A CG1 1 
ATOM   2503  C  CG2 . ILE A 1 336 ? 182.814 157.947 165.126 1.00 45.62  ? 336  ILE A CG2 1 
ATOM   2504  C  CD1 . ILE A 1 336 ? 184.520 157.570 162.642 1.00 45.62  ? 336  ILE A CD1 1 
ATOM   2505  N  N   . VAL A 1 337 ? 183.529 160.626 166.972 1.00 42.53  ? 337  VAL A N   1 
ATOM   2506  C  CA  . VAL A 1 337 ? 183.344 160.834 168.406 1.00 42.53  ? 337  VAL A CA  1 
ATOM   2507  C  C   . VAL A 1 337 ? 182.461 162.047 168.646 1.00 42.53  ? 337  VAL A C   1 
ATOM   2508  O  O   . VAL A 1 337 ? 181.391 161.953 169.263 1.00 42.53  ? 337  VAL A O   1 
ATOM   2509  C  CB  . VAL A 1 337 ? 184.705 160.992 169.105 1.00 42.53  ? 337  VAL A CB  1 
ATOM   2510  C  CG1 . VAL A 1 337 ? 184.505 161.438 170.541 1.00 42.53  ? 337  VAL A CG1 1 
ATOM   2511  C  CG2 . VAL A 1 337 ? 185.491 159.697 169.038 1.00 42.53  ? 337  VAL A CG2 1 
ATOM   2512  N  N   . THR A 1 338 ? 182.874 163.196 168.109 1.00 45.34  ? 338  THR A N   1 
ATOM   2513  C  CA  . THR A 1 338 ? 182.126 164.424 168.334 1.00 45.34  ? 338  THR A CA  1 
ATOM   2514  C  C   . THR A 1 338 ? 180.708 164.298 167.795 1.00 45.34  ? 338  THR A C   1 
ATOM   2515  O  O   . THR A 1 338 ? 179.759 164.811 168.398 1.00 45.34  ? 338  THR A O   1 
ATOM   2516  C  CB  . THR A 1 338 ? 182.855 165.602 167.688 1.00 45.34  ? 338  THR A CB  1 
ATOM   2517  O  OG1 . THR A 1 338 ? 184.213 165.624 168.141 1.00 45.34  ? 338  THR A OG1 1 
ATOM   2518  C  CG2 . THR A 1 338 ? 182.207 166.906 168.085 1.00 45.34  ? 338  THR A CG2 1 
ATOM   2519  N  N   . SER A 1 339 ? 180.536 163.578 166.684 1.00 43.91  ? 339  SER A N   1 
ATOM   2520  C  CA  . SER A 1 339 ? 179.203 163.443 166.111 1.00 43.91  ? 339  SER A CA  1 
ATOM   2521  C  C   . SER A 1 339 ? 178.338 162.495 166.928 1.00 43.91  ? 339  SER A C   1 
ATOM   2522  O  O   . SER A 1 339 ? 177.107 162.605 166.909 1.00 43.91  ? 339  SER A O   1 
ATOM   2523  C  CB  . SER A 1 339 ? 179.293 162.964 164.662 1.00 43.91  ? 339  SER A CB  1 
ATOM   2524  O  OG  . SER A 1 339 ? 179.889 161.683 164.586 1.00 43.91  ? 339  SER A OG  1 
ATOM   2525  N  N   . THR A 1 340 ? 178.954 161.558 167.650 1.00 39.07  ? 340  THR A N   1 
ATOM   2526  C  CA  . THR A 1 340 ? 178.161 160.580 168.387 1.00 39.07  ? 340  THR A CA  1 
ATOM   2527  C  C   . THR A 1 340 ? 177.918 161.033 169.820 1.00 39.07  ? 340  THR A C   1 
ATOM   2528  O  O   . THR A 1 340 ? 176.768 161.235 170.231 1.00 39.07  ? 340  THR A O   1 
ATOM   2529  C  CB  . THR A 1 340 ? 178.850 159.216 168.367 1.00 39.07  ? 340  THR A CB  1 
ATOM   2530  O  OG1 . THR A 1 340 ? 179.303 158.930 167.039 1.00 39.07  ? 340  THR A OG1 1 
ATOM   2531  C  CG2 . THR A 1 340 ? 177.884 158.132 168.808 1.00 39.07  ? 340  THR A CG2 1 
ATOM   2532  N  N   . LEU A 1 341 ? 178.995 161.226 170.587 1.00 35.15  ? 341  LEU A N   1 
ATOM   2533  C  CA  . LEU A 1 341 ? 178.861 161.506 172.013 1.00 35.15  ? 341  LEU A CA  1 
ATOM   2534  C  C   . LEU A 1 341 ? 177.994 162.732 172.260 1.00 35.15  ? 341  LEU A C   1 
ATOM   2535  O  O   . LEU A 1 341 ? 177.075 162.689 173.088 1.00 35.15  ? 341  LEU A O   1 
ATOM   2536  C  CB  . LEU A 1 341 ? 180.240 161.690 172.642 1.00 35.15  ? 341  LEU A CB  1 
ATOM   2537  C  CG  . LEU A 1 341 ? 181.112 160.439 172.742 1.00 35.15  ? 341  LEU A CG  1 
ATOM   2538  C  CD1 . LEU A 1 341 ? 182.299 160.688 173.655 1.00 35.15  ? 341  LEU A CD1 1 
ATOM   2539  C  CD2 . LEU A 1 341 ? 180.297 159.258 173.236 1.00 35.15  ? 341  LEU A CD2 1 
ATOM   2540  N  N   . ALA A 1 342 ? 178.250 163.822 171.530 1.00 37.03  ? 342  ALA A N   1 
ATOM   2541  C  CA  . ALA A 1 342 ? 177.438 165.022 171.689 1.00 37.03  ? 342  ALA A CA  1 
ATOM   2542  C  C   . ALA A 1 342 ? 175.959 164.717 171.520 1.00 37.03  ? 342  ALA A C   1 
ATOM   2543  O  O   . ALA A 1 342 ? 175.141 165.176 172.327 1.00 37.03  ? 342  ALA A O   1 
ATOM   2544  C  CB  . ALA A 1 342 ? 177.875 166.096 170.694 1.00 37.03  ? 342  ALA A CB  1 
ATOM   2545  N  N   . ARG A 1 343 ? 175.604 163.916 170.510 1.00 38.34  ? 343  ARG A N   1 
ATOM   2546  C  CA  . ARG A 1 343 ? 174.213 163.511 170.343 1.00 38.34  ? 343  ARG A CA  1 
ATOM   2547  C  C   . ARG A 1 343 ? 173.680 162.896 171.628 1.00 38.34  ? 343  ARG A C   1 
ATOM   2548  O  O   . ARG A 1 343 ? 172.660 163.344 172.168 1.00 38.34  ? 343  ARG A O   1 
ATOM   2549  C  CB  . ARG A 1 343 ? 174.092 162.528 169.177 1.00 38.34  ? 343  ARG A CB  1 
ATOM   2550  C  CG  . ARG A 1 343 ? 172.787 161.739 169.125 1.00 38.34  ? 343  ARG A CG  1 
ATOM   2551  C  CD  . ARG A 1 343 ? 171.554 162.639 169.153 1.00 38.34  ? 343  ARG A CD  1 
ATOM   2552  N  NE  . ARG A 1 343 ? 170.322 161.900 168.900 1.00 38.34  ? 343  ARG A NE  1 
ATOM   2553  C  CZ  . ARG A 1 343 ? 169.805 160.987 169.712 1.00 38.34  ? 343  ARG A CZ  1 
ATOM   2554  N  NH1 . ARG A 1 343 ? 170.372 160.688 170.869 1.00 38.34  ? 343  ARG A NH1 1 
ATOM   2555  N  NH2 . ARG A 1 343 ? 168.687 160.361 169.355 1.00 38.34  ? 343  ARG A NH2 1 
ATOM   2556  N  N   . GLY A 1 344 ? 174.395 161.905 172.165 1.00 34.78  ? 344  GLY A N   1 
ATOM   2557  C  CA  . GLY A 1 344 ? 173.984 161.324 173.430 1.00 34.78  ? 344  GLY A CA  1 
ATOM   2558  C  C   . GLY A 1 344 ? 173.885 162.373 174.517 1.00 34.78  ? 344  GLY A C   1 
ATOM   2559  O  O   . GLY A 1 344 ? 172.914 162.408 175.279 1.00 34.78  ? 344  GLY A O   1 
ATOM   2560  N  N   . ALA A 1 345 ? 174.867 163.277 174.566 1.00 34.22  ? 345  ALA A N   1 
ATOM   2561  C  CA  . ALA A 1 345 ? 174.826 164.369 175.529 1.00 34.22  ? 345  ALA A CA  1 
ATOM   2562  C  C   . ALA A 1 345 ? 173.523 165.143 175.404 1.00 34.22  ? 345  ALA A C   1 
ATOM   2563  O  O   . ALA A 1 345 ? 172.841 165.400 176.403 1.00 34.22  ? 345  ALA A O   1 
ATOM   2564  C  CB  . ALA A 1 345 ? 176.029 165.291 175.332 1.00 34.22  ? 345  ALA A CB  1 
ATOM   2565  N  N   . VAL A 1 346 ? 173.134 165.475 174.169 1.00 34.65  ? 346  VAL A N   1 
ATOM   2566  C  CA  . VAL A 1 346 ? 171.875 166.182 173.971 1.00 34.65  ? 346  VAL A CA  1 
ATOM   2567  C  C   . VAL A 1 346 ? 170.720 165.348 174.501 1.00 34.65  ? 346  VAL A C   1 
ATOM   2568  O  O   . VAL A 1 346 ? 169.855 165.853 175.229 1.00 34.65  ? 346  VAL A O   1 
ATOM   2569  C  CB  . VAL A 1 346 ? 171.684 166.542 172.488 1.00 34.65  ? 346  VAL A CB  1 
ATOM   2570  C  CG1 . VAL A 1 346 ? 170.330 167.197 172.275 1.00 34.65  ? 346  VAL A CG1 1 
ATOM   2571  C  CG2 . VAL A 1 346 ? 172.798 167.462 172.023 1.00 34.65  ? 346  VAL A CG2 1 
ATOM   2572  N  N   . LYS A 1 347 ? 170.711 164.050 174.188 1.00 35.18  ? 347  LYS A N   1 
ATOM   2573  C  CA  . LYS A 1 347 ? 169.680 163.181 174.739 1.00 35.18  ? 347  LYS A CA  1 
ATOM   2574  C  C   . LYS A 1 347 ? 169.763 163.150 176.257 1.00 35.18  ? 347  LYS A C   1 
ATOM   2575  O  O   . LYS A 1 347 ? 168.734 163.160 176.944 1.00 35.18  ? 347  LYS A O   1 
ATOM   2576  C  CB  . LYS A 1 347 ? 169.808 161.772 174.162 1.00 35.18  ? 347  LYS A CB  1 
ATOM   2577  C  CG  . LYS A 1 347 ? 168.722 160.820 174.629 1.00 35.18  ? 347  LYS A CG  1 
ATOM   2578  C  CD  . LYS A 1 347 ? 168.183 159.990 173.479 1.00 35.18  ? 347  LYS A CD  1 
ATOM   2579  C  CE  . LYS A 1 347 ? 166.902 159.275 173.873 1.00 35.18  ? 347  LYS A CE  1 
ATOM   2580  N  NZ  . LYS A 1 347 ? 166.273 158.592 172.710 1.00 35.18  ? 347  LYS A NZ  1 
ATOM   2581  N  N   . LEU A 1 348 ? 170.982 163.146 176.800 1.00 31.69  ? 348  LEU A N   1 
ATOM   2582  C  CA  . LEU A 1 348 ? 171.131 163.181 178.249 1.00 31.69  ? 348  LEU A CA  1 
ATOM   2583  C  C   . LEU A 1 348 ? 170.590 164.484 178.818 1.00 31.69  ? 348  LEU A C   1 
ATOM   2584  O  O   . LEU A 1 348 ? 170.094 164.515 179.951 1.00 31.69  ? 348  LEU A O   1 
ATOM   2585  C  CB  . LEU A 1 348 ? 172.596 162.981 178.633 1.00 31.69  ? 348  LEU A CB  1 
ATOM   2586  C  CG  . LEU A 1 348 ? 172.975 161.516 178.853 1.00 31.69  ? 348  LEU A CG  1 
ATOM   2587  C  CD1 . LEU A 1 348 ? 174.333 161.361 179.510 1.00 31.69  ? 348  LEU A CD1 1 
ATOM   2588  C  CD2 . LEU A 1 348 ? 171.903 160.814 179.670 1.00 31.69  ? 348  LEU A CD2 1 
ATOM   2589  N  N   . SER A 1 349 ? 170.657 165.567 178.042 1.00 31.30  ? 349  SER A N   1 
ATOM   2590  C  CA  . SER A 1 349 ? 170.084 166.824 178.498 1.00 31.30  ? 349  SER A CA  1 
ATOM   2591  C  C   . SER A 1 349 ? 168.567 166.780 178.556 1.00 31.30  ? 349  SER A C   1 
ATOM   2592  O  O   . SER A 1 349 ? 167.964 167.630 179.219 1.00 31.30  ? 349  SER A O   1 
ATOM   2593  C  CB  . SER A 1 349 ? 170.540 167.963 177.594 1.00 31.30  ? 349  SER A CB  1 
ATOM   2594  O  OG  . SER A 1 349 ? 171.952 168.034 177.575 1.00 31.30  ? 349  SER A OG  1 
ATOM   2595  N  N   . LYS A 1 350 ? 167.938 165.819 177.879 1.00 32.18  ? 350  LYS A N   1 
ATOM   2596  C  CA  . LYS A 1 350 ? 166.503 165.617 177.990 1.00 32.18  ? 350  LYS A CA  1 
ATOM   2597  C  C   . LYS A 1 350 ? 166.136 164.625 179.083 1.00 32.18  ? 350  LYS A C   1 
ATOM   2598  O  O   . LYS A 1 350 ? 164.945 164.428 179.346 1.00 32.18  ? 350  LYS A O   1 
ATOM   2599  C  CB  . LYS A 1 350 ? 165.929 165.151 176.647 1.00 32.18  ? 350  LYS A CB  1 
ATOM   2600  C  CG  . LYS A 1 350 ? 166.224 166.107 175.501 1.00 32.18  ? 350  LYS A CG  1 
ATOM   2601  C  CD  . LYS A 1 350 ? 165.316 165.855 174.310 1.00 32.18  ? 350  LYS A CD  1 
ATOM   2602  C  CE  . LYS A 1 350 ? 165.907 166.439 173.036 1.00 32.18  ? 350  LYS A CE  1 
ATOM   2603  N  NZ  . LYS A 1 350 ? 167.021 165.607 172.503 1.00 32.18  ? 350  LYS A NZ  1 
ATOM   2604  N  N   . GLN A 1 351 ? 167.127 164.004 179.722 1.00 33.38  ? 351  GLN A N   1 
ATOM   2605  C  CA  . GLN A 1 351 ? 166.912 163.120 180.858 1.00 33.38  ? 351  GLN A CA  1 
ATOM   2606  C  C   . GLN A 1 351 ? 167.407 163.731 182.163 1.00 33.38  ? 351  GLN A C   1 
ATOM   2607  O  O   . GLN A 1 351 ? 167.716 162.996 183.107 1.00 33.38  ? 351  GLN A O   1 
ATOM   2608  C  CB  . GLN A 1 351 ? 167.589 161.771 180.615 1.00 33.38  ? 351  GLN A CB  1 
ATOM   2609  C  CG  . GLN A 1 351 ? 167.156 161.087 179.331 1.00 33.38  ? 351  GLN A CG  1 
ATOM   2610  C  CD  . GLN A 1 351 ? 167.575 159.633 179.276 1.00 33.38  ? 351  GLN A CD  1 
ATOM   2611  O  OE1 . GLN A 1 351 ? 168.232 159.129 180.187 1.00 33.38  ? 351  GLN A OE1 1 
ATOM   2612  N  NE2 . GLN A 1 351 ? 167.193 158.947 178.205 1.00 33.38  ? 351  GLN A NE2 1 
ATOM   2613  N  N   . LYS A 1 352 ? 167.498 165.063 182.226 1.00 31.33  ? 352  LYS A N   1 
ATOM   2614  C  CA  . LYS A 1 352 ? 167.944 165.787 183.419 1.00 31.33  ? 352  LYS A CA  1 
ATOM   2615  C  C   . LYS A 1 352 ? 169.369 165.388 183.813 1.00 31.33  ? 352  LYS A C   1 
ATOM   2616  O  O   . LYS A 1 352 ? 169.704 165.292 184.994 1.00 31.33  ? 352  LYS A O   1 
ATOM   2617  C  CB  . LYS A 1 352 ? 166.972 165.583 184.585 1.00 31.33  ? 352  LYS A CB  1 
ATOM   2618  C  CG  . LYS A 1 352 ? 165.790 166.537 184.575 1.00 31.33  ? 352  LYS A CG  1 
ATOM   2619  C  CD  . LYS A 1 352 ? 164.848 166.269 185.734 1.00 31.33  ? 352  LYS A CD  1 
ATOM   2620  C  CE  . LYS A 1 352 ? 163.931 165.097 185.438 1.00 31.33  ? 352  LYS A CE  1 
ATOM   2621  N  NZ  . LYS A 1 352 ? 162.829 164.993 186.433 1.00 31.33  ? 352  LYS A NZ  1 
ATOM   2622  N  N   . VAL A 1 353 ? 170.211 165.158 182.805 1.00 29.72  ? 353  VAL A N   1 
ATOM   2623  C  CA  . VAL A 1 353 ? 171.613 164.812 183.020 1.00 29.72  ? 353  VAL A CA  1 
ATOM   2624  C  C   . VAL A 1 353 ? 172.479 165.625 182.067 1.00 29.72  ? 353  VAL A C   1 
ATOM   2625  O  O   . VAL A 1 353 ? 172.613 165.281 180.888 1.00 29.72  ? 353  VAL A O   1 
ATOM   2626  C  CB  . VAL A 1 353 ? 171.856 163.302 182.826 1.00 29.72  ? 353  VAL A CB  1 
ATOM   2627  C  CG1 . VAL A 1 353 ? 173.335 162.984 182.926 1.00 29.72  ? 353  VAL A CG1 1 
ATOM   2628  C  CG2 . VAL A 1 353 ? 171.077 162.492 183.845 1.00 29.72  ? 353  VAL A CG2 1 
ATOM   2629  N  N   . ILE A 1 354 ? 173.073 166.707 182.560 1.00 31.79  ? 354  ILE A N   1 
ATOM   2630  C  CA  . ILE A 1 354 ? 173.930 167.569 181.757 1.00 31.79  ? 354  ILE A CA  1 
ATOM   2631  C  C   . ILE A 1 354 ? 175.354 167.043 181.835 1.00 31.79  ? 354  ILE A C   1 
ATOM   2632  O  O   . ILE A 1 354 ? 175.881 166.801 182.930 1.00 31.79  ? 354  ILE A O   1 
ATOM   2633  C  CB  . ILE A 1 354 ? 173.857 169.030 182.232 1.00 31.79  ? 354  ILE A CB  1 
ATOM   2634  C  CG1 . ILE A 1 354 ? 172.402 169.458 182.428 1.00 31.79  ? 354  ILE A CG1 1 
ATOM   2635  C  CG2 . ILE A 1 354 ? 174.536 169.938 181.228 1.00 31.79  ? 354  ILE A CG2 1 
ATOM   2636  C  CD1 . ILE A 1 354 ? 171.542 169.288 181.197 1.00 31.79  ? 354  ILE A CD1 1 
ATOM   2637  N  N   . VAL A 1 355 ? 175.979 166.864 180.675 1.00 30.98  ? 355  VAL A N   1 
ATOM   2638  C  CA  . VAL A 1 355 ? 177.344 166.366 180.574 1.00 30.98  ? 355  VAL A CA  1 
ATOM   2639  C  C   . VAL A 1 355 ? 178.245 167.543 180.229 1.00 30.98  ? 355  VAL A C   1 
ATOM   2640  O  O   . VAL A 1 355 ? 178.136 168.120 179.140 1.00 30.98  ? 355  VAL A O   1 
ATOM   2641  C  CB  . VAL A 1 355 ? 177.462 165.253 179.524 1.00 30.98  ? 355  VAL A CB  1 
ATOM   2642  C  CG1 . VAL A 1 355 ? 178.896 164.789 179.406 1.00 30.98  ? 355  VAL A CG1 1 
ATOM   2643  C  CG2 . VAL A 1 355 ? 176.553 164.099 179.885 1.00 30.98  ? 355  VAL A CG2 1 
ATOM   2644  N  N   . LYS A 1 356 ? 179.137 167.897 181.154 1.00 31.18  ? 356  LYS A N   1 
ATOM   2645  C  CA  . LYS A 1 356 ? 179.999 169.055 180.946 1.00 31.18  ? 356  LYS A CA  1 
ATOM   2646  C  C   . LYS A 1 356 ? 181.039 168.815 179.859 1.00 31.18  ? 356  LYS A C   1 
ATOM   2647  O  O   . LYS A 1 356 ? 181.301 169.716 179.054 1.00 31.18  ? 356  LYS A O   1 
ATOM   2648  C  CB  . LYS A 1 356 ? 180.679 169.440 182.260 1.00 31.18  ? 356  LYS A CB  1 
ATOM   2649  C  CG  . LYS A 1 356 ? 179.732 170.066 183.274 1.00 31.18  ? 356  LYS A CG  1 
ATOM   2650  C  CD  . LYS A 1 356 ? 180.417 170.326 184.606 1.00 31.18  ? 356  LYS A CD  1 
ATOM   2651  C  CE  . LYS A 1 356 ? 181.803 170.915 184.416 1.00 31.18  ? 356  LYS A CE  1 
ATOM   2652  N  NZ  . LYS A 1 356 ? 182.307 171.549 185.664 1.00 31.18  ? 356  LYS A NZ  1 
ATOM   2653  N  N   . HIS A 1 357 ? 181.633 167.625 179.810 1.00 36.66  ? 357  HIS A N   1 
ATOM   2654  C  CA  . HIS A 1 357 ? 182.620 167.283 178.792 1.00 36.66  ? 357  HIS A CA  1 
ATOM   2655  C  C   . HIS A 1 357 ? 182.320 165.887 178.268 1.00 36.66  ? 357  HIS A C   1 
ATOM   2656  O  O   . HIS A 1 357 ? 181.988 164.989 179.047 1.00 36.66  ? 357  HIS A O   1 
ATOM   2657  C  CB  . HIS A 1 357 ? 184.045 167.372 179.350 1.00 36.66  ? 357  HIS A CB  1 
ATOM   2658  C  CG  . HIS A 1 357 ? 184.380 166.297 180.336 1.00 36.66  ? 357  HIS A CG  1 
ATOM   2659  N  ND1 . HIS A 1 357 ? 185.466 165.463 180.187 1.00 36.66  ? 357  HIS A ND1 1 
ATOM   2660  C  CD2 . HIS A 1 357 ? 183.775 165.926 181.489 1.00 36.66  ? 357  HIS A CD2 1 
ATOM   2661  C  CE1 . HIS A 1 357 ? 185.515 164.620 181.203 1.00 36.66  ? 357  HIS A CE1 1 
ATOM   2662  N  NE2 . HIS A 1 357 ? 184.500 164.880 182.008 1.00 36.66  ? 357  HIS A NE2 1 
ATOM   2663  N  N   . LEU A 1 358 ? 182.450 165.708 176.950 1.00 37.16  ? 358  LEU A N   1 
ATOM   2664  C  CA  . LEU A 1 358 ? 182.000 164.478 176.302 1.00 37.16  ? 358  LEU A CA  1 
ATOM   2665  C  C   . LEU A 1 358 ? 182.731 163.245 176.817 1.00 37.16  ? 358  LEU A C   1 
ATOM   2666  O  O   . LEU A 1 358 ? 182.166 162.144 176.813 1.00 37.16  ? 358  LEU A O   1 
ATOM   2667  C  CB  . LEU A 1 358 ? 182.176 164.597 174.788 1.00 37.16  ? 358  LEU A CB  1 
ATOM   2668  C  CG  . LEU A 1 358 ? 181.328 165.664 174.094 1.00 37.16  ? 358  LEU A CG  1 
ATOM   2669  C  CD1 . LEU A 1 358 ? 181.492 165.583 172.587 1.00 37.16  ? 358  LEU A CD1 1 
ATOM   2670  C  CD2 . LEU A 1 358 ? 179.867 165.519 174.483 1.00 37.16  ? 358  LEU A CD2 1 
ATOM   2671  N  N   . ASP A 1 359 ? 183.980 163.407 177.262 1.00 42.67  ? 359  ASP A N   1 
ATOM   2672  C  CA  . ASP A 1 359 ? 184.758 162.279 177.767 1.00 42.67  ? 359  ASP A CA  1 
ATOM   2673  C  C   . ASP A 1 359 ? 183.990 161.517 178.840 1.00 42.67  ? 359  ASP A C   1 
ATOM   2674  O  O   . ASP A 1 359 ? 184.002 160.281 178.872 1.00 42.67  ? 359  ASP A O   1 
ATOM   2675  C  CB  . ASP A 1 359 ? 186.097 162.784 178.314 1.00 42.67  ? 359  ASP A CB  1 
ATOM   2676  C  CG  . ASP A 1 359 ? 186.993 161.667 178.826 1.00 42.67  ? 359  ASP A CG  1 
ATOM   2677  O  OD1 . ASP A 1 359 ? 186.658 160.479 178.651 1.00 42.67  ? 359  ASP A OD1 1 
ATOM   2678  O  OD2 . ASP A 1 359 ? 188.045 161.984 179.420 1.00 42.67  ? 359  ASP A OD2 1 
ATOM   2679  N  N   . ALA A 1 360 ? 183.290 162.244 179.711 1.00 36.38  ? 360  ALA A N   1 
ATOM   2680  C  CA  . ALA A 1 360 ? 182.548 161.640 180.808 1.00 36.38  ? 360  ALA A CA  1 
ATOM   2681  C  C   . ALA A 1 360 ? 181.600 160.561 180.302 1.00 36.38  ? 360  ALA A C   1 
ATOM   2682  O  O   . ALA A 1 360 ? 181.438 159.523 180.953 1.00 36.38  ? 360  ALA A O   1 
ATOM   2683  C  CB  . ALA A 1 360 ? 181.772 162.706 181.581 1.00 36.38  ? 360  ALA A CB  1 
ATOM   2684  N  N   . ILE A 1 361 ? 181.006 160.779 179.126 1.00 35.45  ? 361  ILE A N   1 
ATOM   2685  C  CA  . ILE A 1 361 ? 180.050 159.832 178.571 1.00 35.45  ? 361  ILE A CA  1 
ATOM   2686  C  C   . ILE A 1 361 ? 180.637 158.436 178.431 1.00 35.45  ? 361  ILE A C   1 
ATOM   2687  O  O   . ILE A 1 361 ? 179.910 157.447 178.572 1.00 35.45  ? 361  ILE A O   1 
ATOM   2688  C  CB  . ILE A 1 361 ? 179.523 160.349 177.213 1.00 35.45  ? 361  ILE A CB  1 
ATOM   2689  C  CG1 . ILE A 1 361 ? 178.772 161.666 177.404 1.00 35.45  ? 361  ILE A CG1 1 
ATOM   2690  C  CG2 . ILE A 1 361 ? 178.604 159.335 176.561 1.00 35.45  ? 361  ILE A CG2 1 
ATOM   2691  C  CD1 . ILE A 1 361 ? 178.394 162.345 176.109 1.00 35.45  ? 361  ILE A CD1 1 
ATOM   2692  N  N   . GLN A 1 362 ? 181.945 158.325 178.192 1.00 39.59  ? 362  GLN A N   1 
ATOM   2693  C  CA  . GLN A 1 362 ? 182.588 157.017 178.251 1.00 39.59  ? 362  GLN A CA  1 
ATOM   2694  C  C   . GLN A 1 362 ? 182.587 156.479 179.676 1.00 39.59  ? 362  GLN A C   1 
ATOM   2695  O  O   . GLN A 1 362 ? 182.016 155.418 179.953 1.00 39.59  ? 362  GLN A O   1 
ATOM   2696  C  CB  . GLN A 1 362 ? 184.020 157.100 177.720 1.00 39.59  ? 362  GLN A CB  1 
ATOM   2697  C  CG  . GLN A 1 362 ? 184.809 155.817 177.925 1.00 39.59  ? 362  GLN A CG  1 
ATOM   2698  C  CD  . GLN A 1 362 ? 186.308 156.034 177.899 1.00 39.59  ? 362  GLN A CD  1 
ATOM   2699  O  OE1 . GLN A 1 362 ? 186.780 157.158 177.751 1.00 39.59  ? 362  GLN A OE1 1 
ATOM   2700  N  NE2 . GLN A 1 362 ? 187.065 154.952 178.043 1.00 39.59  ? 362  GLN A NE2 1 
ATOM   2701  N  N   . ASN A 1 363 ? 183.210 157.217 180.598 1.00 39.18  ? 363  ASN A N   1 
ATOM   2702  C  CA  . ASN A 1 363 ? 183.336 156.742 181.972 1.00 39.18  ? 363  ASN A CA  1 
ATOM   2703  C  C   . ASN A 1 363 ? 181.970 156.580 182.624 1.00 39.18  ? 363  ASN A C   1 
ATOM   2704  O  O   . ASN A 1 363 ? 181.754 155.647 183.407 1.00 39.18  ? 363  ASN A O   1 
ATOM   2705  C  CB  . ASN A 1 363 ? 184.209 157.699 182.782 1.00 39.18  ? 363  ASN A CB  1 
ATOM   2706  C  CG  . ASN A 1 363 ? 185.675 157.606 182.411 1.00 39.18  ? 363  ASN A CG  1 
ATOM   2707  O  OD1 . ASN A 1 363 ? 186.254 158.550 181.876 1.00 39.18  ? 363  ASN A OD1 1 
ATOM   2708  N  ND2 . ASN A 1 363 ? 186.285 156.462 182.696 1.00 39.18  ? 363  ASN A ND2 1 
ATOM   2709  N  N   . PHE A 1 364 ? 181.032 157.472 182.303 1.00 37.03  ? 364  PHE A N   1 
ATOM   2710  C  CA  . PHE A 1 364 ? 179.697 157.385 182.883 1.00 37.03  ? 364  PHE A CA  1 
ATOM   2711  C  C   . PHE A 1 364 ? 178.991 156.109 182.449 1.00 37.03  ? 364  PHE A C   1 
ATOM   2712  O  O   . PHE A 1 364 ? 178.012 155.694 183.080 1.00 37.03  ? 364  PHE A O   1 
ATOM   2713  C  CB  . PHE A 1 364 ? 178.884 158.619 182.493 1.00 37.03  ? 364  PHE A CB  1 
ATOM   2714  C  CG  . PHE A 1 364 ? 177.590 158.756 183.231 1.00 37.03  ? 364  PHE A CG  1 
ATOM   2715  C  CD1 . PHE A 1 364 ? 177.582 159.153 184.557 1.00 37.03  ? 364  PHE A CD1 1 
ATOM   2716  C  CD2 . PHE A 1 364 ? 176.384 158.532 182.599 1.00 37.03  ? 364  PHE A CD2 1 
ATOM   2717  C  CE1 . PHE A 1 364 ? 176.397 159.296 185.246 1.00 37.03  ? 364  PHE A CE1 1 
ATOM   2718  C  CE2 . PHE A 1 364 ? 175.198 158.680 183.283 1.00 37.03  ? 364  PHE A CE2 1 
ATOM   2719  C  CZ  . PHE A 1 364 ? 175.203 159.059 184.607 1.00 37.03  ? 364  PHE A CZ  1 
ATOM   2720  N  N   . GLY A 1 365 ? 179.467 155.476 181.379 1.00 40.11  ? 365  GLY A N   1 
ATOM   2721  C  CA  . GLY A 1 365 ? 178.947 154.189 180.969 1.00 40.11  ? 365  GLY A CA  1 
ATOM   2722  C  C   . GLY A 1 365 ? 179.776 153.033 181.489 1.00 40.11  ? 365  GLY A C   1 
ATOM   2723  O  O   . GLY A 1 365 ? 179.289 151.902 181.577 1.00 40.11  ? 365  GLY A O   1 
ATOM   2724  N  N   . ALA A 1 366 ? 181.033 153.304 181.836 1.00 41.00  ? 366  ALA A N   1 
ATOM   2725  C  CA  . ALA A 1 366 ? 181.942 152.283 182.339 1.00 41.00  ? 366  ALA A CA  1 
ATOM   2726  C  C   . ALA A 1 366 ? 181.954 152.196 183.858 1.00 41.00  ? 366  ALA A C   1 
ATOM   2727  O  O   . ALA A 1 366 ? 182.703 151.384 184.412 1.00 41.00  ? 366  ALA A O   1 
ATOM   2728  C  CB  . ALA A 1 366 ? 183.363 152.543 181.829 1.00 41.00  ? 366  ALA A CB  1 
ATOM   2729  N  N   . MET A 1 367 ? 181.151 153.011 184.536 1.00 40.05  ? 367  MET A N   1 
ATOM   2730  C  CA  . MET A 1 367 ? 181.106 152.998 185.991 1.00 40.05  ? 367  MET A CA  1 
ATOM   2731  C  C   . MET A 1 367 ? 180.577 151.665 186.505 1.00 40.05  ? 367  MET A C   1 
ATOM   2732  O  O   . MET A 1 367 ? 179.589 151.134 185.989 1.00 40.05  ? 367  MET A O   1 
ATOM   2733  C  CB  . MET A 1 367 ? 180.226 154.143 186.489 1.00 40.05  ? 367  MET A CB  1 
ATOM   2734  C  CG  . MET A 1 367 ? 180.346 154.437 187.969 1.00 40.05  ? 367  MET A CG  1 
ATOM   2735  S  SD  . MET A 1 367 ? 179.337 155.852 188.444 1.00 40.05  ? 367  MET A SD  1 
ATOM   2736  C  CE  . MET A 1 367 ? 177.828 155.502 187.547 1.00 40.05  ? 367  MET A CE  1 
ATOM   2737  N  N   . ASP A 1 368 ? 181.241 151.122 187.527 1.00 43.24  ? 368  ASP A N   1 
ATOM   2738  C  CA  . ASP A 1 368 ? 180.778 149.910 188.185 1.00 43.24  ? 368  ASP A CA  1 
ATOM   2739  C  C   . ASP A 1 368 ? 180.762 150.022 189.702 1.00 43.24  ? 368  ASP A C   1 
ATOM   2740  O  O   . ASP A 1 368 ? 180.217 149.133 190.365 1.00 43.24  ? 368  ASP A O   1 
ATOM   2741  C  CB  . ASP A 1 368 ? 181.639 148.704 187.774 1.00 43.24  ? 368  ASP A CB  1 
ATOM   2742  C  CG  . ASP A 1 368 ? 183.093 148.863 188.166 1.00 43.24  ? 368  ASP A CG  1 
ATOM   2743  O  OD1 . ASP A 1 368 ? 183.522 150.009 188.414 1.00 43.24  ? 368  ASP A OD1 1 
ATOM   2744  O  OD2 . ASP A 1 368 ? 183.808 147.841 188.230 1.00 43.24  ? 368  ASP A OD2 1 
ATOM   2745  N  N   . ILE A 1 369 ? 181.343 151.077 190.269 1.00 41.09  ? 369  ILE A N   1 
ATOM   2746  C  CA  . ILE A 1 369 ? 181.283 151.344 191.702 1.00 41.09  ? 369  ILE A CA  1 
ATOM   2747  C  C   . ILE A 1 369 ? 180.889 152.806 191.860 1.00 41.09  ? 369  ILE A C   1 
ATOM   2748  O  O   . ILE A 1 369 ? 181.600 153.696 191.380 1.00 41.09  ? 369  ILE A O   1 
ATOM   2749  C  CB  . ILE A 1 369 ? 182.613 151.062 192.415 1.00 41.09  ? 369  ILE A CB  1 
ATOM   2750  C  CG1 . ILE A 1 369 ? 183.008 149.593 192.253 1.00 41.09  ? 369  ILE A CG1 1 
ATOM   2751  C  CG2 . ILE A 1 369 ? 182.514 151.426 193.884 1.00 41.09  ? 369  ILE A CG2 1 
ATOM   2752  C  CD1 . ILE A 1 369 ? 184.321 149.240 192.915 1.00 41.09  ? 369  ILE A CD1 1 
ATOM   2753  N  N   . LEU A 1 370 ? 179.767 153.058 192.525 1.00 36.02  ? 370  LEU A N   1 
ATOM   2754  C  CA  . LEU A 1 370 ? 179.239 154.409 192.698 1.00 36.02  ? 370  LEU A CA  1 
ATOM   2755  C  C   . LEU A 1 370 ? 179.213 154.733 194.187 1.00 36.02  ? 370  LEU A C   1 
ATOM   2756  O  O   . LEU A 1 370 ? 178.376 154.215 194.931 1.00 36.02  ? 370  LEU A O   1 
ATOM   2757  C  CB  . LEU A 1 370 ? 177.852 154.536 192.076 1.00 36.02  ? 370  LEU A CB  1 
ATOM   2758  C  CG  . LEU A 1 370 ? 177.097 155.834 192.367 1.00 36.02  ? 370  LEU A CG  1 
ATOM   2759  C  CD1 . LEU A 1 370 ? 177.728 156.994 191.620 1.00 36.02  ? 370  LEU A CD1 1 
ATOM   2760  C  CD2 . LEU A 1 370 ? 175.629 155.698 192.000 1.00 36.02  ? 370  LEU A CD2 1 
ATOM   2761  N  N   . CYS A 1 371 ? 180.135 155.588 194.620 1.00 36.30  ? 371  CYS A N   1 
ATOM   2762  C  CA  . CYS A 1 371 ? 180.151 156.051 195.999 1.00 36.30  ? 371  CYS A CA  1 
ATOM   2763  C  C   . CYS A 1 371 ? 179.232 157.255 196.156 1.00 36.30  ? 371  CYS A C   1 
ATOM   2764  O  O   . CYS A 1 371 ? 179.212 158.153 195.310 1.00 36.30  ? 371  CYS A O   1 
ATOM   2765  C  CB  . CYS A 1 371 ? 181.573 156.411 196.426 1.00 36.30  ? 371  CYS A CB  1 
ATOM   2766  S  SG  . CYS A 1 371 ? 182.831 155.238 195.877 1.00 36.30  ? 371  CYS A SG  1 
ATOM   2767  N  N   . THR A 1 372 ? 178.474 157.276 197.252 1.00 33.92  ? 372  THR A N   1 
ATOM   2768  C  CA  . THR A 1 372 ? 177.467 158.309 197.462 1.00 33.92  ? 372  THR A CA  1 
ATOM   2769  C  C   . THR A 1 372 ? 177.354 158.688 198.933 1.00 33.92  ? 372  THR A C   1 
ATOM   2770  O  O   . THR A 1 372 ? 178.229 158.358 199.739 1.00 33.92  ? 372  THR A O   1 
ATOM   2771  C  CB  . THR A 1 372 ? 176.097 157.847 196.954 1.00 33.92  ? 372  THR A CB  1 
ATOM   2772  O  OG1 . THR A 1 372 ? 175.868 156.491 197.356 1.00 33.92  ? 372  THR A OG1 1 
ATOM   2773  C  CG2 . THR A 1 372 ? 176.006 157.947 195.439 1.00 33.92  ? 372  THR A CG2 1 
ATOM   2774  N  N   . ASP A 1 373 ? 176.279 159.387 199.283 1.00 36.94  ? 373  ASP A N   1 
ATOM   2775  C  CA  . ASP A 1 373 ? 175.995 159.769 200.659 1.00 36.94  ? 373  ASP A CA  1 
ATOM   2776  C  C   . ASP A 1 373 ? 174.530 159.469 200.934 1.00 36.94  ? 373  ASP A C   1 
ATOM   2777  O  O   . ASP A 1 373 ? 173.705 159.473 200.017 1.00 36.94  ? 373  ASP A O   1 
ATOM   2778  C  CB  . ASP A 1 373 ? 176.304 161.254 200.904 1.00 36.94  ? 373  ASP A CB  1 
ATOM   2779  C  CG  . ASP A 1 373 ? 176.243 161.636 202.374 1.00 36.94  ? 373  ASP A CG  1 
ATOM   2780  O  OD1 . ASP A 1 373 ? 175.165 161.504 202.990 1.00 36.94  ? 373  ASP A OD1 1 
ATOM   2781  O  OD2 . ASP A 1 373 ? 177.280 162.074 202.916 1.00 36.94  ? 373  ASP A OD2 1 
ATOM   2782  N  N   . LYS A 1 374 ? 174.220 159.203 202.205 1.00 36.38  ? 374  LYS A N   1 
ATOM   2783  C  CA  . LYS A 1 374 ? 172.852 158.853 202.575 1.00 36.38  ? 374  LYS A CA  1 
ATOM   2784  C  C   . LYS A 1 374 ? 171.894 160.015 202.332 1.00 36.38  ? 374  LYS A C   1 
ATOM   2785  O  O   . LYS A 1 374 ? 170.771 159.815 201.857 1.00 36.38  ? 374  LYS A O   1 
ATOM   2786  C  CB  . LYS A 1 374 ? 172.805 158.399 204.036 1.00 36.38  ? 374  LYS A CB  1 
ATOM   2787  C  CG  . LYS A 1 374 ? 173.405 159.386 205.024 1.00 36.38  ? 374  LYS A CG  1 
ATOM   2788  C  CD  . LYS A 1 374 ? 173.332 158.859 206.445 1.00 36.38  ? 374  LYS A CD  1 
ATOM   2789  C  CE  . LYS A 1 374 ? 171.900 158.842 206.948 1.00 36.38  ? 374  LYS A CE  1 
ATOM   2790  N  NZ  . LYS A 1 374 ? 171.328 160.213 207.027 1.00 36.38  ? 374  LYS A NZ  1 
ATOM   2791  N  N   . THR A 1 375 ? 172.319 161.234 202.652 1.00 34.98  ? 375  THR A N   1 
ATOM   2792  C  CA  . THR A 1 375 ? 171.461 162.395 202.468 1.00 34.98  ? 375  THR A CA  1 
ATOM   2793  C  C   . THR A 1 375 ? 171.269 162.692 200.985 1.00 34.98  ? 375  THR A C   1 
ATOM   2794  O  O   . THR A 1 375 ? 172.198 162.584 200.180 1.00 34.98  ? 375  THR A O   1 
ATOM   2795  C  CB  . THR A 1 375 ? 172.055 163.615 203.173 1.00 34.98  ? 375  THR A CB  1 
ATOM   2796  O  OG1 . THR A 1 375 ? 172.559 163.229 204.456 1.00 34.98  ? 375  THR A OG1 1 
ATOM   2797  C  CG2 . THR A 1 375 ? 170.998 164.690 203.358 1.00 34.98  ? 375  THR A CG2 1 
ATOM   2798  N  N   . GLY A 1 376 ? 170.046 163.073 200.627 1.00 35.39  ? 376  GLY A N   1 
ATOM   2799  C  CA  . GLY A 1 376 ? 169.738 163.450 199.262 1.00 35.39  ? 376  GLY A CA  1 
ATOM   2800  C  C   . GLY A 1 376 ? 169.483 162.283 198.331 1.00 35.39  ? 376  GLY A C   1 
ATOM   2801  O  O   . GLY A 1 376 ? 168.421 162.206 197.705 1.00 35.39  ? 376  GLY A O   1 
ATOM   2802  N  N   . THR A 1 377 ? 170.446 161.366 198.227 1.00 35.85  ? 377  THR A N   1 
ATOM   2803  C  CA  . THR A 1 377 ? 170.303 160.238 197.312 1.00 35.85  ? 377  THR A CA  1 
ATOM   2804  C  C   . THR A 1 377 ? 169.399 159.159 197.899 1.00 35.85  ? 377  THR A C   1 
ATOM   2805  O  O   . THR A 1 377 ? 168.345 158.842 197.338 1.00 35.85  ? 377  THR A O   1 
ATOM   2806  C  CB  . THR A 1 377 ? 171.677 159.657 196.973 1.00 35.85  ? 377  THR A CB  1 
ATOM   2807  O  OG1 . THR A 1 377 ? 172.157 158.888 198.082 1.00 35.85  ? 377  THR A OG1 1 
ATOM   2808  C  CG2 . THR A 1 377 ? 172.665 160.770 196.674 1.00 35.85  ? 377  THR A CG2 1 
ATOM   2809  N  N   . LEU A 1 378 ? 169.797 158.585 199.033 1.00 35.58  ? 378  LEU A N   1 
ATOM   2810  C  CA  . LEU A 1 378 ? 169.009 157.536 199.666 1.00 35.58  ? 378  LEU A CA  1 
ATOM   2811  C  C   . LEU A 1 378 ? 167.786 158.127 200.354 1.00 35.58  ? 378  LEU A C   1 
ATOM   2812  O  O   . LEU A 1 378 ? 166.649 157.773 200.028 1.00 35.58  ? 378  LEU A O   1 
ATOM   2813  C  CB  . LEU A 1 378 ? 169.860 156.753 200.666 1.00 35.58  ? 378  LEU A CB  1 
ATOM   2814  C  CG  . LEU A 1 378 ? 170.489 155.458 200.147 1.00 35.58  ? 378  LEU A CG  1 
ATOM   2815  C  CD1 . LEU A 1 378 ? 171.501 155.747 199.050 1.00 35.58  ? 378  LEU A CD1 1 
ATOM   2816  C  CD2 . LEU A 1 378 ? 171.132 154.687 201.285 1.00 35.58  ? 378  LEU A CD2 1 
ATOM   2817  N  N   . THR A 1 379 ? 168.008 159.030 201.304 1.00 36.83  ? 379  THR A N   1 
ATOM   2818  C  CA  . THR A 1 379 ? 166.902 159.672 201.993 1.00 36.83  ? 379  THR A CA  1 
ATOM   2819  C  C   . THR A 1 379 ? 166.648 161.062 201.412 1.00 36.83  ? 379  THR A C   1 
ATOM   2820  O  O   . THR A 1 379 ? 167.450 161.608 200.649 1.00 36.83  ? 379  THR A O   1 
ATOM   2821  C  CB  . THR A 1 379 ? 167.187 159.770 203.489 1.00 36.83  ? 379  THR A CB  1 
ATOM   2822  O  OG1 . THR A 1 379 ? 168.349 160.582 203.701 1.00 36.83  ? 379  THR A OG1 1 
ATOM   2823  C  CG2 . THR A 1 379 ? 167.434 158.390 204.070 1.00 36.83  ? 379  THR A CG2 1 
ATOM   2824  N  N   . GLN A 1 380 ? 165.548 161.669 201.820 1.00 37.40  ? 380  GLN A N   1 
ATOM   2825  C  CA  . GLN A 1 380 ? 165.206 162.981 201.327 1.00 37.40  ? 380  GLN A CA  1 
ATOM   2826  C  C   . GLN A 1 380 ? 165.910 164.043 202.119 1.00 37.40  ? 380  GLN A C   1 
ATOM   2827  O  O   . GLN A 1 380 ? 166.482 163.771 203.140 1.00 37.40  ? 380  GLN A O   1 
ATOM   2828  C  CB  . GLN A 1 380 ? 163.721 163.214 201.430 1.00 37.40  ? 380  GLN A CB  1 
ATOM   2829  C  CG  . GLN A 1 380 ? 162.893 161.972 201.288 1.00 37.40  ? 380  GLN A CG  1 
ATOM   2830  C  CD  . GLN A 1 380 ? 161.445 162.240 201.578 1.00 37.40  ? 380  GLN A CD  1 
ATOM   2831  O  OE1 . GLN A 1 380 ? 160.630 161.340 201.620 1.00 37.40  ? 380  GLN A OE1 1 
ATOM   2832  N  NE2 . GLN A 1 380 ? 161.121 163.488 201.782 1.00 37.40  ? 380  GLN A NE2 1 
ATOM   2833  N  N   . ASP A 1 381 ? 165.862 165.269 201.634 1.00 43.65  ? 381  ASP A N   1 
ATOM   2834  C  CA  . ASP A 1 381 ? 166.495 166.387 202.318 1.00 43.65  ? 381  ASP A CA  1 
ATOM   2835  C  C   . ASP A 1 381 ? 165.565 167.054 203.319 1.00 43.65  ? 381  ASP A C   1 
ATOM   2836  O  O   . ASP A 1 381 ? 165.980 167.994 204.005 1.00 43.65  ? 381  ASP A O   1 
ATOM   2837  C  CB  . ASP A 1 381 ? 166.994 167.419 201.299 1.00 43.65  ? 381  ASP A CB  1 
ATOM   2838  C  CG  . ASP A 1 381 ? 168.045 168.350 201.876 1.00 43.65  ? 381  ASP A CG  1 
ATOM   2839  O  OD1 . ASP A 1 381 ? 169.205 167.915 202.038 1.00 43.65  ? 381  ASP A OD1 1 
ATOM   2840  O  OD2 . ASP A 1 381 ? 167.711 169.517 202.169 1.00 43.65  ? 381  ASP A OD2 1 
ATOM   2841  N  N   . LYS A 1 382 ? 164.324 166.591 203.424 1.00 44.32  ? 382  LYS A N   1 
ATOM   2842  C  CA  . LYS A 1 382 ? 163.347 167.130 204.357 1.00 44.32  ? 382  LYS A CA  1 
ATOM   2843  C  C   . LYS A 1 382 ? 163.024 166.081 205.410 1.00 44.32  ? 382  LYS A C   1 
ATOM   2844  O  O   . LYS A 1 382 ? 162.776 164.916 205.083 1.00 44.32  ? 382  LYS A O   1 
ATOM   2845  C  CB  . LYS A 1 382 ? 162.070 167.555 203.629 1.00 44.32  ? 382  LYS A CB  1 
ATOM   2846  C  CG  . LYS A 1 382 ? 161.004 168.140 204.534 1.00 44.32  ? 382  LYS A CG  1 
ATOM   2847  C  CD  . LYS A 1 382 ? 159.745 168.475 203.754 1.00 44.32  ? 382  LYS A CD  1 
ATOM   2848  C  CE  . LYS A 1 382 ? 158.718 169.152 204.644 1.00 44.32  ? 382  LYS A CE  1 
ATOM   2849  N  NZ  . LYS A 1 382 ? 158.273 168.254 205.743 1.00 44.32  ? 382  LYS A NZ  1 
ATOM   2850  N  N   . ILE A 1 383 ? 163.027 166.497 206.673 1.00 40.50  ? 383  ILE A N   1 
ATOM   2851  C  CA  . ILE A 1 383 ? 162.801 165.598 207.799 1.00 40.50  ? 383  ILE A CA  1 
ATOM   2852  C  C   . ILE A 1 383 ? 161.356 165.729 208.254 1.00 40.50  ? 383  ILE A C   1 
ATOM   2853  O  O   . ILE A 1 383 ? 160.823 166.842 208.354 1.00 40.50  ? 383  ILE A O   1 
ATOM   2854  C  CB  . ILE A 1 383 ? 163.781 165.884 208.948 1.00 40.50  ? 383  ILE A CB  1 
ATOM   2855  C  CG1 . ILE A 1 383 ? 163.805 167.372 209.294 1.00 40.50  ? 383  ILE A CG1 1 
ATOM   2856  C  CG2 . ILE A 1 383 ? 165.171 165.395 208.585 1.00 40.50  ? 383  ILE A CG2 1 
ATOM   2857  C  CD1 . ILE A 1 383 ? 164.815 167.712 210.363 1.00 40.50  ? 383  ILE A CD1 1 
ATOM   2858  N  N   . VAL A 1 384 ? 160.721 164.590 208.526 1.00 39.66  ? 384  VAL A N   1 
ATOM   2859  C  CA  . VAL A 1 384 ? 159.285 164.586 208.790 1.00 39.66  ? 384  VAL A CA  1 
ATOM   2860  C  C   . VAL A 1 384 ? 159.001 164.739 210.277 1.00 39.66  ? 384  VAL A C   1 
ATOM   2861  O  O   . VAL A 1 384 ? 158.306 165.670 210.699 1.00 39.66  ? 384  VAL A O   1 
ATOM   2862  C  CB  . VAL A 1 384 ? 158.639 163.309 208.223 1.00 39.66  ? 384  VAL A CB  1 
ATOM   2863  C  CG1 . VAL A 1 384 ? 157.216 163.168 208.738 1.00 39.66  ? 384  VAL A CG1 1 
ATOM   2864  C  CG2 . VAL A 1 384 ? 158.652 163.343 206.706 1.00 39.66  ? 384  VAL A CG2 1 
ATOM   2865  N  N   . LEU A 1 385 ? 159.529 163.834 211.092 1.00 34.80  ? 385  LEU A N   1 
ATOM   2866  C  CA  . LEU A 1 385 ? 159.280 163.829 212.524 1.00 34.80  ? 385  LEU A CA  1 
ATOM   2867  C  C   . LEU A 1 385 ? 160.486 164.392 213.257 1.00 34.80  ? 385  LEU A C   1 
ATOM   2868  O  O   . LEU A 1 385 ? 161.626 164.005 212.984 1.00 34.80  ? 385  LEU A O   1 
ATOM   2869  C  CB  . LEU A 1 385 ? 158.978 162.416 213.026 1.00 34.80  ? 385  LEU A CB  1 
ATOM   2870  C  CG  . LEU A 1 385 ? 158.665 162.239 214.511 1.00 34.80  ? 385  LEU A CG  1 
ATOM   2871  C  CD1 . LEU A 1 385 ? 157.547 161.233 214.680 1.00 34.80  ? 385  LEU A CD1 1 
ATOM   2872  C  CD2 . LEU A 1 385 ? 159.899 161.789 215.278 1.00 34.80  ? 385  LEU A CD2 1 
ATOM   2873  N  N   . GLU A 1 386 ? 160.228 165.309 214.184 1.00 36.15  ? 386  GLU A N   1 
ATOM   2874  C  CA  . GLU A 1 386 ? 161.285 165.860 215.016 1.00 36.15  ? 386  GLU A CA  1 
ATOM   2875  C  C   . GLU A 1 386 ? 160.693 166.227 216.367 1.00 36.15  ? 386  GLU A C   1 
ATOM   2876  O  O   . GLU A 1 386 ? 159.612 166.818 216.439 1.00 36.15  ? 386  GLU A O   1 
ATOM   2877  C  CB  . GLU A 1 386 ? 161.945 167.078 214.357 1.00 36.15  ? 386  GLU A CB  1 
ATOM   2878  C  CG  . GLU A 1 386 ? 161.018 168.257 214.120 1.00 36.15  ? 386  GLU A CG  1 
ATOM   2879  C  CD  . GLU A 1 386 ? 161.076 169.272 215.242 1.00 36.15  ? 386  GLU A CD  1 
ATOM   2880  O  OE1 . GLU A 1 386 ? 162.090 169.294 215.971 1.00 36.15  ? 386  GLU A OE1 1 
ATOM   2881  O  OE2 . GLU A 1 386 ? 160.107 170.044 215.398 1.00 36.15  ? 386  GLU A OE2 1 
ATOM   2882  N  N   . ASN A 1 387 ? 161.395 165.853 217.431 1.00 40.03  ? 387  ASN A N   1 
ATOM   2883  C  CA  . ASN A 1 387 ? 160.981 166.174 218.789 1.00 40.03  ? 387  ASN A CA  1 
ATOM   2884  C  C   . ASN A 1 387 ? 162.165 166.751 219.548 1.00 40.03  ? 387  ASN A C   1 
ATOM   2885  O  O   . ASN A 1 387 ? 163.263 166.186 219.521 1.00 40.03  ? 387  ASN A O   1 
ATOM   2886  C  CB  . ASN A 1 387 ? 160.410 164.943 219.508 1.00 40.03  ? 387  ASN A CB  1 
ATOM   2887  C  CG  . ASN A 1 387 ? 161.302 163.721 219.391 1.00 40.03  ? 387  ASN A CG  1 
ATOM   2888  O  OD1 . ASN A 1 387 ? 162.380 163.772 218.804 1.00 40.03  ? 387  ASN A OD1 1 
ATOM   2889  N  ND2 . ASN A 1 387 ? 160.848 162.608 219.954 1.00 40.03  ? 387  ASN A ND2 1 
ATOM   2890  N  N   . HIS A 1 388 ? 161.941 167.881 220.210 1.00 47.59  ? 388  HIS A N   1 
ATOM   2891  C  CA  . HIS A 1 388 ? 162.972 168.580 220.967 1.00 47.59  ? 388  HIS A CA  1 
ATOM   2892  C  C   . HIS A 1 388 ? 162.765 168.283 222.447 1.00 47.59  ? 388  HIS A C   1 
ATOM   2893  O  O   . HIS A 1 388 ? 161.792 168.743 223.053 1.00 47.59  ? 388  HIS A O   1 
ATOM   2894  C  CB  . HIS A 1 388 ? 162.934 170.080 220.673 1.00 47.59  ? 388  HIS A CB  1 
ATOM   2895  C  CG  . HIS A 1 388 ? 161.630 170.733 221.007 1.00 47.59  ? 388  HIS A CG  1 
ATOM   2896  N  ND1 . HIS A 1 388 ? 161.338 171.215 222.265 1.00 47.59  ? 388  HIS A ND1 1 
ATOM   2897  C  CD2 . HIS A 1 388 ? 160.539 170.986 220.246 1.00 47.59  ? 388  HIS A CD2 1 
ATOM   2898  C  CE1 . HIS A 1 388 ? 160.123 171.735 222.264 1.00 47.59  ? 388  HIS A CE1 1 
ATOM   2899  N  NE2 . HIS A 1 388 ? 159.617 171.609 221.051 1.00 47.59  ? 388  HIS A NE2 1 
ATOM   2900  N  N   . THR A 1 389 ? 163.674 167.501 223.020 1.00 48.02  ? 389  THR A N   1 
ATOM   2901  C  CA  . THR A 1 389 ? 163.585 167.052 224.400 1.00 48.02  ? 389  THR A CA  1 
ATOM   2902  C  C   . THR A 1 389 ? 164.896 167.326 225.125 1.00 48.02  ? 389  THR A C   1 
ATOM   2903  O  O   . THR A 1 389 ? 165.954 167.488 224.513 1.00 48.02  ? 389  THR A O   1 
ATOM   2904  C  CB  . THR A 1 389 ? 163.251 165.556 224.480 1.00 48.02  ? 389  THR A CB  1 
ATOM   2905  O  OG1 . THR A 1 389 ? 164.400 164.789 224.096 1.00 48.02  ? 389  THR A OG1 1 
ATOM   2906  C  CG2 . THR A 1 389 ? 162.085 165.209 223.567 1.00 48.02  ? 389  THR A CG2 1 
ATOM   2907  N  N   . ASP A 1 390 ? 164.813 167.379 226.450 1.00 50.83  ? 390  ASP A N   1 
ATOM   2908  C  CA  . ASP A 1 390 ? 165.993 167.518 227.288 1.00 50.83  ? 390  ASP A CA  1 
ATOM   2909  C  C   . ASP A 1 390 ? 166.586 166.134 227.548 1.00 50.83  ? 390  ASP A C   1 
ATOM   2910  O  O   . ASP A 1 390 ? 166.211 165.143 226.915 1.00 50.83  ? 390  ASP A O   1 
ATOM   2911  C  CB  . ASP A 1 390 ? 165.646 168.253 228.582 1.00 50.83  ? 390  ASP A CB  1 
ATOM   2912  C  CG  . ASP A 1 390 ? 164.546 167.566 229.371 1.00 50.83  ? 390  ASP A CG  1 
ATOM   2913  O  OD1 . ASP A 1 390 ? 164.014 166.541 228.897 1.00 50.83  ? 390  ASP A OD1 1 
ATOM   2914  O  OD2 . ASP A 1 390 ? 164.212 168.054 230.471 1.00 50.83  ? 390  ASP A OD2 1 
ATOM   2915  N  N   . ILE A 1 391 ? 167.528 166.052 228.491 1.00 50.63  ? 391  ILE A N   1 
ATOM   2916  C  CA  . ILE A 1 391 ? 168.173 164.778 228.784 1.00 50.63  ? 391  ILE A CA  1 
ATOM   2917  C  C   . ILE A 1 391 ? 167.206 163.778 229.404 1.00 50.63  ? 391  ILE A C   1 
ATOM   2918  O  O   . ILE A 1 391 ? 167.396 162.566 229.251 1.00 50.63  ? 391  ILE A O   1 
ATOM   2919  C  CB  . ILE A 1 391 ? 169.395 164.991 229.696 1.00 50.63  ? 391  ILE A CB  1 
ATOM   2920  C  CG1 . ILE A 1 391 ? 168.964 165.518 231.065 1.00 50.63  ? 391  ILE A CG1 1 
ATOM   2921  C  CG2 . ILE A 1 391 ? 170.375 165.949 229.045 1.00 50.63  ? 391  ILE A CG2 1 
ATOM   2922  C  CD1 . ILE A 1 391 ? 170.001 165.320 232.146 1.00 50.63  ? 391  ILE A CD1 1 
ATOM   2923  N  N   . SER A 1 392 ? 166.171 164.248 230.099 1.00 53.38  ? 392  SER A N   1 
ATOM   2924  C  CA  . SER A 1 392 ? 165.217 163.362 230.750 1.00 53.38  ? 392  SER A CA  1 
ATOM   2925  C  C   . SER A 1 392 ? 164.179 162.794 229.792 1.00 53.38  ? 392  SER A C   1 
ATOM   2926  O  O   . SER A 1 392 ? 163.443 161.877 230.175 1.00 53.38  ? 392  SER A O   1 
ATOM   2927  C  CB  . SER A 1 392 ? 164.508 164.097 231.893 1.00 53.38  ? 392  SER A CB  1 
ATOM   2928  O  OG  . SER A 1 392 ? 163.868 165.271 231.425 1.00 53.38  ? 392  SER A OG  1 
ATOM   2929  N  N   . GLY A 1 393 ? 164.101 163.308 228.568 1.00 51.12  ? 393  GLY A N   1 
ATOM   2930  C  CA  . GLY A 1 393 ? 163.170 162.819 227.570 1.00 51.12  ? 393  GLY A CA  1 
ATOM   2931  C  C   . GLY A 1 393 ? 161.923 163.657 227.401 1.00 51.12  ? 393  GLY A C   1 
ATOM   2932  O  O   . GLY A 1 393 ? 161.255 163.536 226.366 1.00 51.12  ? 393  GLY A O   1 
ATOM   2933  N  N   . LYS A 1 394 ? 161.582 164.496 228.376 1.00 51.13  ? 394  LYS A N   1 
ATOM   2934  C  CA  . LYS A 1 394 ? 160.414 165.360 228.254 1.00 51.13  ? 394  LYS A CA  1 
ATOM   2935  C  C   . LYS A 1 394 ? 160.701 166.483 227.265 1.00 51.13  ? 394  LYS A C   1 
ATOM   2936  O  O   . LYS A 1 394 ? 161.844 166.937 227.146 1.00 51.13  ? 394  LYS A O   1 
ATOM   2937  C  CB  . LYS A 1 394 ? 160.028 165.924 229.620 1.00 51.13  ? 394  LYS A CB  1 
ATOM   2938  C  CG  . LYS A 1 394 ? 160.989 166.968 230.168 1.00 51.13  ? 394  LYS A CG  1 
ATOM   2939  C  CD  . LYS A 1 394 ? 160.517 167.501 231.509 1.00 51.13  ? 394  LYS A CD  1 
ATOM   2940  C  CE  . LYS A 1 394 ? 160.843 166.531 232.632 1.00 51.13  ? 394  LYS A CE  1 
ATOM   2941  N  NZ  . LYS A 1 394 ? 162.309 166.438 232.872 1.00 51.13  ? 394  LYS A NZ  1 
ATOM   2942  N  N   . THR A 1 395 ? 159.669 166.923 226.545 1.00 49.37  ? 395  THR A N   1 
ATOM   2943  C  CA  . THR A 1 395 ? 159.821 168.033 225.613 1.00 49.37  ? 395  THR A CA  1 
ATOM   2944  C  C   . THR A 1 395 ? 160.230 169.299 226.357 1.00 49.37  ? 395  THR A C   1 
ATOM   2945  O  O   . THR A 1 395 ? 159.675 169.618 227.414 1.00 49.37  ? 395  THR A O   1 
ATOM   2946  C  CB  . THR A 1 395 ? 158.530 168.248 224.810 1.00 49.37  ? 395  THR A CB  1 
ATOM   2947  O  OG1 . THR A 1 395 ? 158.749 169.240 223.798 1.00 49.37  ? 395  THR A OG1 1 
ATOM   2948  C  CG2 . THR A 1 395 ? 157.369 168.670 225.707 1.00 49.37  ? 395  THR A CG2 1 
ATOM   2949  N  N   . SER A 1 396 ? 161.226 170.007 225.835 1.00 52.51  ? 396  SER A N   1 
ATOM   2950  C  CA  . SER A 1 396 ? 161.744 171.216 226.461 1.00 52.51  ? 396  SER A CA  1 
ATOM   2951  C  C   . SER A 1 396 ? 161.689 172.358 225.457 1.00 52.51  ? 396  SER A C   1 
ATOM   2952  O  O   . SER A 1 396 ? 162.197 172.230 224.338 1.00 52.51  ? 396  SER A O   1 
ATOM   2953  C  CB  . SER A 1 396 ? 163.174 171.005 226.959 1.00 52.51  ? 396  SER A CB  1 
ATOM   2954  O  OG  . SER A 1 396 ? 163.737 172.223 227.416 1.00 52.51  ? 396  SER A OG  1 
ATOM   2955  N  N   . GLU A 1 397 ? 161.076 173.472 225.860 1.00 58.26  ? 397  GLU A N   1 
ATOM   2956  C  CA  . GLU A 1 397 ? 161.021 174.637 224.985 1.00 58.26  ? 397  GLU A CA  1 
ATOM   2957  C  C   . GLU A 1 397 ? 162.363 175.357 224.935 1.00 58.26  ? 397  GLU A C   1 
ATOM   2958  O  O   . GLU A 1 397 ? 162.669 176.035 223.947 1.00 58.26  ? 397  GLU A O   1 
ATOM   2959  C  CB  . GLU A 1 397 ? 159.916 175.587 225.451 1.00 58.26  ? 397  GLU A CB  1 
ATOM   2960  C  CG  . GLU A 1 397 ? 159.668 176.768 224.529 1.00 58.26  ? 397  GLU A CG  1 
ATOM   2961  C  CD  . GLU A 1 397 ? 158.490 177.613 224.971 1.00 58.26  ? 397  GLU A CD  1 
ATOM   2962  O  OE1 . GLU A 1 397 ? 158.495 178.082 226.128 1.00 58.26  ? 397  GLU A OE1 1 
ATOM   2963  O  OE2 . GLU A 1 397 ? 157.558 177.809 224.162 1.00 58.26  ? 397  GLU A OE2 1 
ATOM   2964  N  N   . ARG A 1 398 ? 163.174 175.219 225.987 1.00 56.77  ? 398  ARG A N   1 
ATOM   2965  C  CA  . ARG A 1 398 ? 164.484 175.864 226.013 1.00 56.77  ? 398  ARG A CA  1 
ATOM   2966  C  C   . ARG A 1 398 ? 165.378 175.340 224.897 1.00 56.77  ? 398  ARG A C   1 
ATOM   2967  O  O   . ARG A 1 398 ? 166.081 176.111 224.233 1.00 56.77  ? 398  ARG A O   1 
ATOM   2968  C  CB  . ARG A 1 398 ? 165.144 175.652 227.375 1.00 56.77  ? 398  ARG A CB  1 
ATOM   2969  C  CG  . ARG A 1 398 ? 166.506 176.309 227.511 1.00 56.77  ? 398  ARG A CG  1 
ATOM   2970  C  CD  . ARG A 1 398 ? 166.402 177.823 227.486 1.00 56.77  ? 398  ARG A CD  1 
ATOM   2971  N  NE  . ARG A 1 398 ? 165.570 178.327 228.572 1.00 56.77  ? 398  ARG A NE  1 
ATOM   2972  C  CZ  . ARG A 1 398 ? 166.006 178.552 229.804 1.00 56.77  ? 398  ARG A CZ  1 
ATOM   2973  N  NH1 . ARG A 1 398 ? 167.264 178.327 230.144 1.00 56.77  ? 398  ARG A NH1 1 
ATOM   2974  N  NH2 . ARG A 1 398 ? 165.157 179.015 230.718 1.00 56.77  ? 398  ARG A NH2 1 
ATOM   2975  N  N   . VAL A 1 399 ? 165.368 174.022 224.681 1.00 50.48  ? 399  VAL A N   1 
ATOM   2976  C  CA  . VAL A 1 399 ? 166.191 173.428 223.631 1.00 50.48  ? 399  VAL A CA  1 
ATOM   2977  C  C   . VAL A 1 399 ? 165.764 173.945 222.266 1.00 50.48  ? 399  VAL A C   1 
ATOM   2978  O  O   . VAL A 1 399 ? 166.601 174.307 221.428 1.00 50.48  ? 399  VAL A O   1 
ATOM   2979  C  CB  . VAL A 1 399 ? 166.113 171.892 223.700 1.00 50.48  ? 399  VAL A CB  1 
ATOM   2980  C  CG1 . VAL A 1 399 ? 166.970 171.267 222.613 1.00 50.48  ? 399  VAL A CG1 1 
ATOM   2981  C  CG2 . VAL A 1 399 ? 166.534 171.405 225.074 1.00 50.48  ? 399  VAL A CG2 1 
ATOM   2982  N  N   . LEU A 1 400 ? 164.454 173.986 222.022 1.00 52.16  ? 400  LEU A N   1 
ATOM   2983  C  CA  . LEU A 1 400 ? 163.945 174.466 220.744 1.00 52.16  ? 400  LEU A CA  1 
ATOM   2984  C  C   . LEU A 1 400 ? 164.294 175.933 220.527 1.00 52.16  ? 400  LEU A C   1 
ATOM   2985  O  O   . LEU A 1 400 ? 164.659 176.330 219.418 1.00 52.16  ? 400  LEU A O   1 
ATOM   2986  C  CB  . LEU A 1 400 ? 162.433 174.255 220.667 1.00 52.16  ? 400  LEU A CB  1 
ATOM   2987  C  CG  . LEU A 1 400 ? 161.765 174.691 219.363 1.00 52.16  ? 400  LEU A CG  1 
ATOM   2988  C  CD1 . LEU A 1 400 ? 162.174 173.769 218.227 1.00 52.16  ? 400  LEU A CD1 1 
ATOM   2989  C  CD2 . LEU A 1 400 ? 160.253 174.717 219.516 1.00 52.16  ? 400  LEU A CD2 1 
ATOM   2990  N  N   . HIS A 1 401 ? 164.194 176.752 221.577 1.00 54.92  ? 401  HIS A N   1 
ATOM   2991  C  CA  . HIS A 1 401 ? 164.520 178.167 221.432 1.00 54.92  ? 401  HIS A CA  1 
ATOM   2992  C  C   . HIS A 1 401 ? 166.010 178.376 221.184 1.00 54.92  ? 401  HIS A C   1 
ATOM   2993  O  O   . HIS A 1 401 ? 166.397 179.231 220.379 1.00 54.92  ? 401  HIS A O   1 
ATOM   2994  C  CB  . HIS A 1 401 ? 164.060 178.942 222.665 1.00 54.92  ? 401  HIS A CB  1 
ATOM   2995  C  CG  . HIS A 1 401 ? 162.584 179.185 222.705 1.00 54.92  ? 401  HIS A CG  1 
ATOM   2996  N  ND1 . HIS A 1 401 ? 161.778 179.039 221.597 1.00 54.92  ? 401  HIS A ND1 1 
ATOM   2997  C  CD2 . HIS A 1 401 ? 161.769 179.570 223.715 1.00 54.92  ? 401  HIS A CD2 1 
ATOM   2998  C  CE1 . HIS A 1 401 ? 160.529 179.319 221.924 1.00 54.92  ? 401  HIS A CE1 1 
ATOM   2999  N  NE2 . HIS A 1 401 ? 160.496 179.645 223.203 1.00 54.92  ? 401  HIS A NE2 1 
ATOM   3000  N  N   . SER A 1 402 ? 166.865 177.612 221.868 1.00 53.59  ? 402  SER A N   1 
ATOM   3001  C  CA  . SER A 1 402 ? 168.300 177.720 221.621 1.00 53.59  ? 402  SER A CA  1 
ATOM   3002  C  C   . SER A 1 402 ? 168.646 177.297 220.199 1.00 53.59  ? 402  SER A C   1 
ATOM   3003  O  O   . SER A 1 402 ? 169.450 177.954 219.521 1.00 53.59  ? 402  SER A O   1 
ATOM   3004  C  CB  . SER A 1 402 ? 169.076 176.881 222.635 1.00 53.59  ? 402  SER A CB  1 
ATOM   3005  O  OG  . SER A 1 402 ? 168.926 177.401 223.944 1.00 53.59  ? 402  SER A OG  1 
ATOM   3006  N  N   . ALA A 1 403 ? 168.047 176.202 219.727 1.00 52.88  ? 403  ALA A N   1 
ATOM   3007  C  CA  . ALA A 1 403 ? 168.268 175.783 218.349 1.00 52.88  ? 403  ALA A CA  1 
ATOM   3008  C  C   . ALA A 1 403 ? 167.755 176.822 217.363 1.00 52.88  ? 403  ALA A C   1 
ATOM   3009  O  O   . ALA A 1 403 ? 168.388 177.054 216.328 1.00 52.88  ? 403  ALA A O   1 
ATOM   3010  C  CB  . ALA A 1 403 ? 167.603 174.432 218.093 1.00 52.88  ? 403  ALA A CB  1 
ATOM   3011  N  N   . TRP A 1 404 ? 166.618 177.453 217.662 1.00 56.70  ? 404  TRP A N   1 
ATOM   3012  C  CA  . TRP A 1 404 ? 166.106 178.504 216.792 1.00 56.70  ? 404  TRP A CA  1 
ATOM   3013  C  C   . TRP A 1 404 ? 167.063 179.684 216.737 1.00 56.70  ? 404  TRP A C   1 
ATOM   3014  O  O   . TRP A 1 404 ? 167.296 180.245 215.663 1.00 56.70  ? 404  TRP A O   1 
ATOM   3015  C  CB  . TRP A 1 404 ? 164.728 178.961 217.264 1.00 56.70  ? 404  TRP A CB  1 
ATOM   3016  C  CG  . TRP A 1 404 ? 164.105 179.970 216.354 1.00 56.70  ? 404  TRP A CG  1 
ATOM   3017  C  CD1 . TRP A 1 404 ? 163.231 179.725 215.338 1.00 56.70  ? 404  TRP A CD1 1 
ATOM   3018  C  CD2 . TRP A 1 404 ? 164.316 181.387 216.369 1.00 56.70  ? 404  TRP A CD2 1 
ATOM   3019  N  NE1 . TRP A 1 404 ? 162.879 180.900 214.721 1.00 56.70  ? 404  TRP A NE1 1 
ATOM   3020  C  CE2 . TRP A 1 404 ? 163.533 181.936 215.336 1.00 56.70  ? 404  TRP A CE2 1 
ATOM   3021  C  CE3 . TRP A 1 404 ? 165.088 182.245 217.158 1.00 56.70  ? 404  TRP A CE3 1 
ATOM   3022  C  CZ2 . TRP A 1 404 ? 163.500 183.302 215.070 1.00 56.70  ? 404  TRP A CZ2 1 
ATOM   3023  C  CZ3 . TRP A 1 404 ? 165.055 183.599 216.891 1.00 56.70  ? 404  TRP A CZ3 1 
ATOM   3024  C  CH2 . TRP A 1 404 ? 164.266 184.115 215.858 1.00 56.70  ? 404  TRP A CH2 1 
ATOM   3025  N  N   . LEU A 1 405 ? 167.612 180.084 217.884 1.00 55.83  ? 405  LEU A N   1 
ATOM   3026  C  CA  . LEU A 1 405 ? 168.583 181.172 217.896 1.00 55.83  ? 405  LEU A CA  1 
ATOM   3027  C  C   . LEU A 1 405 ? 169.798 180.822 217.047 1.00 55.83  ? 405  LEU A C   1 
ATOM   3028  O  O   . LEU A 1 405 ? 170.233 181.616 216.200 1.00 55.83  ? 405  LEU A O   1 
ATOM   3029  C  CB  . LEU A 1 405 ? 169.002 181.483 219.332 1.00 55.83  ? 405  LEU A CB  1 
ATOM   3030  C  CG  . LEU A 1 405 ? 168.069 182.391 220.132 1.00 55.83  ? 405  LEU A CG  1 
ATOM   3031  C  CD1 . LEU A 1 405 ? 168.462 182.402 221.599 1.00 55.83  ? 405  LEU A CD1 1 
ATOM   3032  C  CD2 . LEU A 1 405 ? 168.087 183.795 219.558 1.00 55.83  ? 405  LEU A CD2 1 
ATOM   3033  N  N   . ASN A 1 406 ? 170.341 179.618 217.242 1.00 52.69  ? 406  ASN A N   1 
ATOM   3034  C  CA  . ASN A 1 406 ? 171.529 179.210 216.498 1.00 52.69  ? 406  ASN A CA  1 
ATOM   3035  C  C   . ASN A 1 406 ? 171.251 179.144 215.000 1.00 52.69  ? 406  ASN A C   1 
ATOM   3036  O  O   . ASN A 1 406 ? 172.100 179.532 214.189 1.00 52.69  ? 406  ASN A O   1 
ATOM   3037  C  CB  . ASN A 1 406 ? 172.032 177.862 217.015 1.00 52.69  ? 406  ASN A CB  1 
ATOM   3038  C  CG  . ASN A 1 406 ? 173.364 177.459 216.408 1.00 52.69  ? 406  ASN A CG  1 
ATOM   3039  O  OD1 . ASN A 1 406 ? 173.466 177.212 215.208 1.00 52.69  ? 406  ASN A OD1 1 
ATOM   3040  N  ND2 . ASN A 1 406 ? 174.393 177.387 217.243 1.00 52.69  ? 406  ASN A ND2 1 
ATOM   3041  N  N   . SER A 1 407 ? 170.071 178.655 214.612 1.00 54.32  ? 407  SER A N   1 
ATOM   3042  C  CA  . SER A 1 407 ? 169.758 178.511 213.195 1.00 54.32  ? 407  SER A CA  1 
ATOM   3043  C  C   . SER A 1 407 ? 169.444 179.854 212.548 1.00 54.32  ? 407  SER A C   1 
ATOM   3044  O  O   . SER A 1 407 ? 169.782 180.080 211.381 1.00 54.32  ? 407  SER A O   1 
ATOM   3045  C  CB  . SER A 1 407 ? 168.585 177.550 213.015 1.00 54.32  ? 407  SER A CB  1 
ATOM   3046  O  OG  . SER A 1 407 ? 168.949 176.233 213.388 1.00 54.32  ? 407  SER A OG  1 
ATOM   3047  N  N   . HIS A 1 408 ? 168.784 180.752 213.280 1.00 57.58  ? 408  HIS A N   1 
ATOM   3048  C  CA  . HIS A 1 408 ? 168.381 182.025 212.698 1.00 57.58  ? 408  HIS A CA  1 
ATOM   3049  C  C   . HIS A 1 408 ? 169.558 182.983 212.596 1.00 57.58  ? 408  HIS A C   1 
ATOM   3050  O  O   . HIS A 1 408 ? 169.660 183.748 211.630 1.00 57.58  ? 408  HIS A O   1 
ATOM   3051  C  CB  . HIS A 1 408 ? 167.252 182.638 213.526 1.00 57.58  ? 408  HIS A CB  1 
ATOM   3052  C  CG  . HIS A 1 408 ? 166.727 183.927 212.976 1.00 57.58  ? 408  HIS A CG  1 
ATOM   3053  N  ND1 . HIS A 1 408 ? 165.858 183.981 211.908 1.00 57.58  ? 408  HIS A ND1 1 
ATOM   3054  C  CD2 . HIS A 1 408 ? 166.942 185.210 213.352 1.00 57.58  ? 408  HIS A CD2 1 
ATOM   3055  C  CE1 . HIS A 1 408 ? 165.563 185.242 211.647 1.00 57.58  ? 408  HIS A CE1 1 
ATOM   3056  N  NE2 . HIS A 1 408 ? 166.208 186.007 212.508 1.00 57.58  ? 408  HIS A NE2 1 
ATOM   3057  N  N   . TYR A 1 409 ? 170.461 182.957 213.574 1.00 62.19  ? 409  TYR A N   1 
ATOM   3058  C  CA  . TYR A 1 409 ? 171.582 183.885 213.580 1.00 62.19  ? 409  TYR A CA  1 
ATOM   3059  C  C   . TYR A 1 409 ? 172.836 183.320 212.926 1.00 62.19  ? 409  TYR A C   1 
ATOM   3060  O  O   . TYR A 1 409 ? 173.884 183.973 212.965 1.00 62.19  ? 409  TYR A O   1 
ATOM   3061  C  CB  . TYR A 1 409 ? 171.887 184.326 215.013 1.00 62.19  ? 409  TYR A CB  1 
ATOM   3062  C  CG  . TYR A 1 409 ? 170.937 185.389 215.510 1.00 62.19  ? 409  TYR A CG  1 
ATOM   3063  C  CD1 . TYR A 1 409 ? 170.709 186.540 214.768 1.00 62.19  ? 409  TYR A CD1 1 
ATOM   3064  C  CD2 . TYR A 1 409 ? 170.257 185.239 216.710 1.00 62.19  ? 409  TYR A CD2 1 
ATOM   3065  C  CE1 . TYR A 1 409 ? 169.841 187.516 215.210 1.00 62.19  ? 409  TYR A CE1 1 
ATOM   3066  C  CE2 . TYR A 1 409 ? 169.385 186.211 217.162 1.00 62.19  ? 409  TYR A CE2 1 
ATOM   3067  C  CZ  . TYR A 1 409 ? 169.182 187.347 216.407 1.00 62.19  ? 409  TYR A CZ  1 
ATOM   3068  O  OH  . TYR A 1 409 ? 168.316 188.320 216.847 1.00 62.19  ? 409  TYR A OH  1 
ATOM   3069  N  N   . GLN A 1 410 ? 172.761 182.131 212.334 1.00 59.41  ? 410  GLN A N   1 
ATOM   3070  C  CA  . GLN A 1 410 ? 173.882 181.599 211.578 1.00 59.41  ? 410  GLN A CA  1 
ATOM   3071  C  C   . GLN A 1 410 ? 173.963 182.263 210.206 1.00 59.41  ? 410  GLN A C   1 
ATOM   3072  O  O   . GLN A 1 410 ? 172.996 182.843 209.705 1.00 59.41  ? 410  GLN A O   1 
ATOM   3073  C  CB  . GLN A 1 410 ? 173.750 180.086 211.411 1.00 59.41  ? 410  GLN A CB  1 
ATOM   3074  C  CG  . GLN A 1 410 ? 172.760 179.683 210.332 1.00 59.41  ? 410  GLN A CG  1 
ATOM   3075  C  CD  . GLN A 1 410 ? 172.899 178.236 209.916 1.00 59.41  ? 410  GLN A CD  1 
ATOM   3076  O  OE1 . GLN A 1 410 ? 173.744 177.508 210.433 1.00 59.41  ? 410  GLN A OE1 1 
ATOM   3077  N  NE2 . GLN A 1 410 ? 172.064 177.809 208.978 1.00 59.41  ? 410  GLN A NE2 1 
ATOM   3078  N  N   . THR A 1 411 ? 175.145 182.176 209.596 1.00 62.18  ? 411  THR A N   1 
ATOM   3079  C  CA  . THR A 1 411 ? 175.355 182.672 208.244 1.00 62.18  ? 411  THR A CA  1 
ATOM   3080  C  C   . THR A 1 411 ? 176.015 181.649 207.332 1.00 62.18  ? 411  THR A C   1 
ATOM   3081  O  O   . THR A 1 411 ? 176.431 182.007 206.225 1.00 62.18  ? 411  THR A O   1 
ATOM   3082  C  CB  . THR A 1 411 ? 176.198 183.955 208.261 1.00 62.18  ? 411  THR A CB  1 
ATOM   3083  O  OG1 . THR A 1 411 ? 177.370 183.751 209.059 1.00 62.18  ? 411  THR A OG1 1 
ATOM   3084  C  CG2 . THR A 1 411 ? 175.394 185.117 208.824 1.00 62.18  ? 411  THR A CG2 1 
ATOM   3085  N  N   . GLY A 1 412 ? 176.125 180.396 207.760 1.00 57.45  ? 412  GLY A N   1 
ATOM   3086  C  CA  . GLY A 1 412 ? 176.699 179.355 206.939 1.00 57.45  ? 412  GLY A CA  1 
ATOM   3087  C  C   . GLY A 1 412 ? 175.680 178.752 205.991 1.00 57.45  ? 412  GLY A C   1 
ATOM   3088  O  O   . GLY A 1 412 ? 174.648 179.342 205.667 1.00 57.45  ? 412  GLY A O   1 
ATOM   3089  N  N   . LEU A 1 413 ? 175.993 177.543 205.535 1.00 54.91  ? 413  LEU A N   1 
ATOM   3090  C  CA  . LEU A 1 413 ? 175.093 176.826 204.644 1.00 54.91  ? 413  LEU A CA  1 
ATOM   3091  C  C   . LEU A 1 413 ? 173.809 176.446 205.368 1.00 54.91  ? 413  LEU A C   1 
ATOM   3092  O  O   . LEU A 1 413 ? 173.827 176.059 206.540 1.00 54.91  ? 413  LEU A O   1 
ATOM   3093  C  CB  . LEU A 1 413 ? 175.773 175.571 204.100 1.00 54.91  ? 413  LEU A CB  1 
ATOM   3094  C  CG  . LEU A 1 413 ? 176.688 175.742 202.889 1.00 54.91  ? 413  LEU A CG  1 
ATOM   3095  C  CD1 . LEU A 1 413 ? 177.132 174.384 202.381 1.00 54.91  ? 413  LEU A CD1 1 
ATOM   3096  C  CD2 . LEU A 1 413 ? 175.983 176.522 201.792 1.00 54.91  ? 413  LEU A CD2 1 
ATOM   3097  N  N   . LYS A 1 414 ? 172.688 176.562 204.663 1.00 57.03  ? 414  LYS A N   1 
ATOM   3098  C  CA  . LYS A 1 414 ? 171.416 176.123 205.212 1.00 57.03  ? 414  LYS A CA  1 
ATOM   3099  C  C   . LYS A 1 414 ? 171.404 174.607 205.373 1.00 57.03  ? 414  LYS A C   1 
ATOM   3100  O  O   . LYS A 1 414 ? 171.936 173.865 204.544 1.00 57.03  ? 414  LYS A O   1 
ATOM   3101  C  CB  . LYS A 1 414 ? 170.261 176.564 204.313 1.00 57.03  ? 414  LYS A CB  1 
ATOM   3102  C  CG  . LYS A 1 414 ? 170.076 178.070 204.234 1.00 57.03  ? 414  LYS A CG  1 
ATOM   3103  C  CD  . LYS A 1 414 ? 169.792 178.662 205.606 1.00 57.03  ? 414  LYS A CD  1 
ATOM   3104  C  CE  . LYS A 1 414 ? 168.440 178.212 206.135 1.00 57.03  ? 414  LYS A CE  1 
ATOM   3105  N  NZ  . LYS A 1 414 ? 168.149 178.796 207.473 1.00 57.03  ? 414  LYS A NZ  1 
ATOM   3106  N  N   . ASN A 1 415 ? 170.786 174.151 206.458 1.00 55.25  ? 415  ASN A N   1 
ATOM   3107  C  CA  . ASN A 1 415 ? 170.731 172.735 206.783 1.00 55.25  ? 415  ASN A CA  1 
ATOM   3108  C  C   . ASN A 1 415 ? 169.282 172.320 206.994 1.00 55.25  ? 415  ASN A C   1 
ATOM   3109  O  O   . ASN A 1 415 ? 168.410 173.147 207.273 1.00 55.25  ? 415  ASN A O   1 
ATOM   3110  C  CB  . ASN A 1 415 ? 171.563 172.414 208.032 1.00 55.25  ? 415  ASN A CB  1 
ATOM   3111  C  CG  . ASN A 1 415 ? 171.918 170.946 208.134 1.00 55.25  ? 415  ASN A CG  1 
ATOM   3112  O  OD1 . ASN A 1 415 ? 172.109 170.270 207.123 1.00 55.25  ? 415  ASN A OD1 1 
ATOM   3113  N  ND2 . ASN A 1 415 ? 172.006 170.442 209.359 1.00 55.25  ? 415  ASN A ND2 1 
ATOM   3114  N  N   . LEU A 1 416 ? 169.035 171.015 206.848 1.00 49.51  ? 416  LEU A N   1 
ATOM   3115  C  CA  . LEU A 1 416 ? 167.689 170.491 207.052 1.00 49.51  ? 416  LEU A CA  1 
ATOM   3116  C  C   . LEU A 1 416 ? 167.220 170.718 208.484 1.00 49.51  ? 416  LEU A C   1 
ATOM   3117  O  O   . LEU A 1 416 ? 166.054 171.061 208.717 1.00 49.51  ? 416  LEU A O   1 
ATOM   3118  C  CB  . LEU A 1 416 ? 167.645 169.007 206.680 1.00 49.51  ? 416  LEU A CB  1 
ATOM   3119  C  CG  . LEU A 1 416 ? 168.642 168.038 207.326 1.00 49.51  ? 416  LEU A CG  1 
ATOM   3120  C  CD1 . LEU A 1 416 ? 168.111 167.454 208.623 1.00 49.51  ? 416  LEU A CD1 1 
ATOM   3121  C  CD2 . LEU A 1 416 ? 169.011 166.929 206.353 1.00 49.51  ? 416  LEU A CD2 1 
ATOM   3122  N  N   . LEU A 1 417 ? 168.116 170.541 209.458 1.00 51.90  ? 417  LEU A N   1 
ATOM   3123  C  CA  . LEU A 1 417 ? 167.756 170.817 210.844 1.00 51.90  ? 417  LEU A CA  1 
ATOM   3124  C  C   . LEU A 1 417 ? 167.407 172.284 211.037 1.00 51.90  ? 417  LEU A C   1 
ATOM   3125  O  O   . LEU A 1 417 ? 166.455 172.610 211.753 1.00 51.90  ? 417  LEU A O   1 
ATOM   3126  C  CB  . LEU A 1 417 ? 168.894 170.413 211.783 1.00 51.90  ? 417  LEU A CB  1 
ATOM   3127  C  CG  . LEU A 1 417 ? 168.628 170.597 213.282 1.00 51.90  ? 417  LEU A CG  1 
ATOM   3128  C  CD1 . LEU A 1 417 ? 169.231 169.459 214.072 1.00 51.90  ? 417  LEU A CD1 1 
ATOM   3129  C  CD2 . LEU A 1 417 ? 169.176 171.923 213.790 1.00 51.90  ? 417  LEU A CD2 1 
ATOM   3130  N  N   . ASP A 1 418 ? 168.174 173.184 210.417 1.00 56.18  ? 418  ASP A N   1 
ATOM   3131  C  CA  . ASP A 1 418 ? 167.899 174.608 210.563 1.00 56.18  ? 418  ASP A CA  1 
ATOM   3132  C  C   . ASP A 1 418 ? 166.526 174.960 210.005 1.00 56.18  ? 418  ASP A C   1 
ATOM   3133  O  O   . ASP A 1 418 ? 165.753 175.683 210.644 1.00 56.18  ? 418  ASP A O   1 
ATOM   3134  C  CB  . ASP A 1 418 ? 168.988 175.424 209.867 1.00 56.18  ? 418  ASP A CB  1 
ATOM   3135  C  CG  . ASP A 1 418 ? 170.344 175.279 210.533 1.00 56.18  ? 418  ASP A CG  1 
ATOM   3136  O  OD1 . ASP A 1 418 ? 170.403 175.275 211.780 1.00 56.18  ? 418  ASP A OD1 1 
ATOM   3137  O  OD2 . ASP A 1 418 ? 171.354 175.172 209.807 1.00 56.18  ? 418  ASP A OD2 1 
ATOM   3138  N  N   . THR A 1 419 ? 166.202 174.442 208.818 1.00 56.61  ? 419  THR A N   1 
ATOM   3139  C  CA  . THR A 1 419 ? 164.897 174.709 208.223 1.00 56.61  ? 419  THR A CA  1 
ATOM   3140  C  C   . THR A 1 419 ? 163.773 174.130 209.073 1.00 56.61  ? 419  THR A C   1 
ATOM   3141  O  O   . THR A 1 419 ? 162.740 174.781 209.277 1.00 56.61  ? 419  THR A O   1 
ATOM   3142  C  CB  . THR A 1 419 ? 164.843 174.142 206.805 1.00 56.61  ? 419  THR A CB  1 
ATOM   3143  O  OG1 . THR A 1 419 ? 165.941 174.656 206.042 1.00 56.61  ? 419  THR A OG1 1 
ATOM   3144  C  CG2 . THR A 1 419 ? 163.538 174.526 206.129 1.00 56.61  ? 419  THR A CG2 1 
ATOM   3145  N  N   . ALA A 1 420 ? 163.954 172.907 209.577 1.00 57.45  ? 420  ALA A N   1 
ATOM   3146  C  CA  . ALA A 1 420 ? 162.917 172.291 210.399 1.00 57.45  ? 420  ALA A CA  1 
ATOM   3147  C  C   . ALA A 1 420 ? 162.697 173.068 211.689 1.00 57.45  ? 420  ALA A C   1 
ATOM   3148  O  O   . ALA A 1 420 ? 161.554 173.261 212.118 1.00 57.45  ? 420  ALA A O   1 
ATOM   3149  C  CB  . ALA A 1 420 ? 163.280 170.841 210.706 1.00 57.45  ? 420  ALA A CB  1 
ATOM   3150  N  N   . VAL A 1 421 ? 163.779 173.518 212.326 1.00 57.02  ? 421  VAL A N   1 
ATOM   3151  C  CA  . VAL A 1 421 ? 163.649 174.293 213.555 1.00 57.02  ? 421  VAL A CA  1 
ATOM   3152  C  C   . VAL A 1 421 ? 162.970 175.627 213.276 1.00 57.02  ? 421  VAL A C   1 
ATOM   3153  O  O   . VAL A 1 421 ? 162.105 176.069 214.042 1.00 57.02  ? 421  VAL A O   1 
ATOM   3154  C  CB  . VAL A 1 421 ? 165.026 174.477 214.217 1.00 57.02  ? 421  VAL A CB  1 
ATOM   3155  C  CG1 . VAL A 1 421 ? 164.937 175.476 215.347 1.00 57.02  ? 421  VAL A CG1 1 
ATOM   3156  C  CG2 . VAL A 1 421 ? 165.542 173.146 214.735 1.00 57.02  ? 421  VAL A CG2 1 
ATOM   3157  N  N   . LEU A 1 422 ? 163.342 176.290 212.177 1.00 59.50  ? 422  LEU A N   1 
ATOM   3158  C  CA  . LEU A 1 422 ? 162.700 177.554 211.831 1.00 59.50  ? 422  LEU A CA  1 
ATOM   3159  C  C   . LEU A 1 422 ? 161.212 177.376 211.560 1.00 59.50  ? 422  LEU A C   1 
ATOM   3160  O  O   . LEU A 1 422 ? 160.405 178.215 211.976 1.00 59.50  ? 422  LEU A O   1 
ATOM   3161  C  CB  . LEU A 1 422 ? 163.387 178.183 210.619 1.00 59.50  ? 422  LEU A CB  1 
ATOM   3162  C  CG  . LEU A 1 422 ? 164.781 178.768 210.851 1.00 59.50  ? 422  LEU A CG  1 
ATOM   3163  C  CD1 . LEU A 1 422 ? 165.306 179.421 209.584 1.00 59.50  ? 422  LEU A CD1 1 
ATOM   3164  C  CD2 . LEU A 1 422 ? 164.753 179.765 211.996 1.00 59.50  ? 422  LEU A CD2 1 
ATOM   3165  N  N   . GLU A 1 423 ? 160.829 176.303 210.869 1.00 64.69  ? 423  GLU A N   1 
ATOM   3166  C  CA  . GLU A 1 423 ? 159.425 176.064 210.563 1.00 64.69  ? 423  GLU A CA  1 
ATOM   3167  C  C   . GLU A 1 423 ? 158.619 175.609 211.772 1.00 64.69  ? 423  GLU A C   1 
ATOM   3168  O  O   . GLU A 1 423 ? 157.427 175.922 211.863 1.00 64.69  ? 423  GLU A O   1 
ATOM   3169  C  CB  . GLU A 1 423 ? 159.296 175.021 209.450 1.00 64.69  ? 423  GLU A CB  1 
ATOM   3170  C  CG  . GLU A 1 423 ? 159.466 175.584 208.051 1.00 64.69  ? 423  GLU A CG  1 
ATOM   3171  C  CD  . GLU A 1 423 ? 159.694 174.503 207.015 1.00 64.69  ? 423  GLU A CD  1 
ATOM   3172  O  OE1 . GLU A 1 423 ? 159.315 173.341 207.274 1.00 64.69  ? 423  GLU A OE1 1 
ATOM   3173  O  OE2 . GLU A 1 423 ? 160.249 174.815 205.940 1.00 64.69  ? 423  GLU A OE2 1 
ATOM   3174  N  N   . GLY A 1 424 ? 159.237 174.882 212.699 1.00 68.06  ? 424  GLY A N   1 
ATOM   3175  C  CA  . GLY A 1 424 ? 158.542 174.356 213.855 1.00 68.06  ? 424  GLY A CA  1 
ATOM   3176  C  C   . GLY A 1 424 ? 158.367 175.310 215.010 1.00 68.06  ? 424  GLY A C   1 
ATOM   3177  O  O   . GLY A 1 424 ? 157.736 174.948 216.007 1.00 68.06  ? 424  GLY A O   1 
ATOM   3178  N  N   . THR A 1 425 ? 158.908 176.519 214.913 1.00 73.05  ? 425  THR A N   1 
ATOM   3179  C  CA  . THR A 1 425 ? 158.766 177.530 215.951 1.00 73.05  ? 425  THR A CA  1 
ATOM   3180  C  C   . THR A 1 425 ? 157.634 178.476 215.577 1.00 73.05  ? 425  THR A C   1 
ATOM   3181  O  O   . THR A 1 425 ? 157.575 178.962 214.442 1.00 73.05  ? 425  THR A O   1 
ATOM   3182  C  CB  . THR A 1 425 ? 160.066 178.312 216.140 1.00 73.05  ? 425  THR A CB  1 
ATOM   3183  O  OG1 . THR A 1 425 ? 161.169 177.399 216.206 1.00 73.05  ? 425  THR A OG1 1 
ATOM   3184  C  CG2 . THR A 1 425 ? 160.015 179.126 217.421 1.00 73.05  ? 425  THR A CG2 1 
ATOM   3185  N  N   . ASP A 1 426 ? 156.738 178.730 216.527 1.00 81.97  ? 426  ASP A N   1 
ATOM   3186  C  CA  . ASP A 1 426 ? 155.602 179.601 216.270 1.00 81.97  ? 426  ASP A CA  1 
ATOM   3187  C  C   . ASP A 1 426 ? 156.071 181.027 215.992 1.00 81.97  ? 426  ASP A C   1 
ATOM   3188  O  O   . ASP A 1 426 ? 157.124 181.469 216.459 1.00 81.97  ? 426  ASP A O   1 
ATOM   3189  C  CB  . ASP A 1 426 ? 154.629 179.580 217.448 1.00 81.97  ? 426  ASP A CB  1 
ATOM   3190  C  CG  . ASP A 1 426 ? 155.327 179.745 218.781 1.00 81.97  ? 426  ASP A CG  1 
ATOM   3191  O  OD1 . ASP A 1 426 ? 156.459 179.238 218.926 1.00 81.97  ? 426  ASP A OD1 1 
ATOM   3192  O  OD2 . ASP A 1 426 ? 154.745 180.382 219.684 1.00 81.97  ? 426  ASP A OD2 1 
ATOM   3193  N  N   . GLU A 1 427 ? 155.264 181.747 215.210 1.00 85.56  ? 427  GLU A N   1 
ATOM   3194  C  CA  . GLU A 1 427 ? 155.651 183.082 214.765 1.00 85.56  ? 427  GLU A CA  1 
ATOM   3195  C  C   . GLU A 1 427 ? 155.814 184.040 215.938 1.00 85.56  ? 427  GLU A C   1 
ATOM   3196  O  O   . GLU A 1 427 ? 156.721 184.880 215.940 1.00 85.56  ? 427  GLU A O   1 
ATOM   3197  C  CB  . GLU A 1 427 ? 154.624 183.621 213.771 1.00 85.56  ? 427  GLU A CB  1 
ATOM   3198  C  CG  . GLU A 1 427 ? 154.949 183.314 212.319 1.00 85.56  ? 427  GLU A CG  1 
ATOM   3199  C  CD  . GLU A 1 427 ? 156.086 184.163 211.786 1.00 85.56  ? 427  GLU A CD  1 
ATOM   3200  O  OE1 . GLU A 1 427 ? 156.168 185.351 212.163 1.00 85.56  ? 427  GLU A OE1 1 
ATOM   3201  O  OE2 . GLU A 1 427 ? 156.898 183.643 210.993 1.00 85.56  ? 427  GLU A OE2 1 
ATOM   3202  N  N   . GLU A 1 428 ? 154.939 183.937 216.942 1.00 86.58  ? 428  GLU A N   1 
ATOM   3203  C  CA  . GLU A 1 428 ? 155.003 184.852 218.078 1.00 86.58  ? 428  GLU A CA  1 
ATOM   3204  C  C   . GLU A 1 428 ? 156.316 184.699 218.838 1.00 86.58  ? 428  GLU A C   1 
ATOM   3205  O  O   . GLU A 1 428 ? 157.024 185.683 219.083 1.00 86.58  ? 428  GLU A O   1 
ATOM   3206  C  CB  . GLU A 1 428 ? 153.811 184.614 219.005 1.00 86.58  ? 428  GLU A CB  1 
ATOM   3207  C  CG  . GLU A 1 428 ? 153.804 185.486 220.251 1.00 86.58  ? 428  GLU A CG  1 
ATOM   3208  C  CD  . GLU A 1 428 ? 153.686 186.965 219.934 1.00 86.58  ? 428  GLU A CD  1 
ATOM   3209  O  OE1 . GLU A 1 428 ? 153.082 187.309 218.895 1.00 86.58  ? 428  GLU A OE1 1 
ATOM   3210  O  OE2 . GLU A 1 428 ? 154.197 187.785 220.725 1.00 86.58  ? 428  GLU A OE2 1 
ATOM   3211  N  N   . SER A 1 429 ? 156.662 183.466 219.214 1.00 79.88  ? 429  SER A N   1 
ATOM   3212  C  CA  . SER A 1 429 ? 157.904 183.242 219.947 1.00 79.88  ? 429  SER A CA  1 
ATOM   3213  C  C   . SER A 1 429 ? 159.118 183.559 219.084 1.00 79.88  ? 429  SER A C   1 
ATOM   3214  O  O   . SER A 1 429 ? 160.120 184.086 219.581 1.00 79.88  ? 429  SER A O   1 
ATOM   3215  C  CB  . SER A 1 429 ? 157.968 181.802 220.452 1.00 79.88  ? 429  SER A CB  1 
ATOM   3216  O  OG  . SER A 1 429 ? 158.058 180.890 219.372 1.00 79.88  ? 429  SER A OG  1 
ATOM   3217  N  N   . ALA A 1 430 ? 159.050 183.240 217.789 1.00 77.12  ? 430  ALA A N   1 
ATOM   3218  C  CA  . ALA A 1 430 ? 160.167 183.526 216.896 1.00 77.12  ? 430  ALA A CA  1 
ATOM   3219  C  C   . ALA A 1 430 ? 160.427 185.024 216.804 1.00 77.12  ? 430  ALA A C   1 
ATOM   3220  O  O   . ALA A 1 430 ? 161.575 185.474 216.895 1.00 77.12  ? 430  ALA A O   1 
ATOM   3221  C  CB  . ALA A 1 430 ? 159.897 182.938 215.511 1.00 77.12  ? 430  ALA A CB  1 
ATOM   3222  N  N   . ARG A 1 431 ? 159.367 185.819 216.638 1.00 81.65  ? 431  ARG A N   1 
ATOM   3223  C  CA  . ARG A 1 431 ? 159.549 187.264 216.563 1.00 81.65  ? 431  ARG A CA  1 
ATOM   3224  C  C   . ARG A 1 431 ? 159.961 187.846 217.910 1.00 81.65  ? 431  ARG A C   1 
ATOM   3225  O  O   . ARG A 1 431 ? 160.741 188.805 217.952 1.00 81.65  ? 431  ARG A O   1 
ATOM   3226  C  CB  . ARG A 1 431 ? 158.276 187.936 216.039 1.00 81.65  ? 431  ARG A CB  1 
ATOM   3227  C  CG  . ARG A 1 431 ? 157.159 188.103 217.056 1.00 81.65  ? 431  ARG A CG  1 
ATOM   3228  C  CD  . ARG A 1 431 ? 155.941 188.762 216.432 1.00 81.65  ? 431  ARG A CD  1 
ATOM   3229  N  NE  . ARG A 1 431 ? 155.200 187.841 215.579 1.00 81.65  ? 431  ARG A NE  1 
ATOM   3230  C  CZ  . ARG A 1 431 ? 155.100 187.957 214.262 1.00 81.65  ? 431  ARG A CZ  1 
ATOM   3231  N  NH1 . ARG A 1 431 ? 155.686 188.948 213.609 1.00 81.65  ? 431  ARG A NH1 1 
ATOM   3232  N  NH2 . ARG A 1 431 ? 154.397 187.056 213.582 1.00 81.65  ? 431  ARG A NH2 1 
ATOM   3233  N  N   . SER A 1 432 ? 159.474 187.274 219.015 1.00 75.95  ? 432  SER A N   1 
ATOM   3234  C  CA  . SER A 1 432 ? 159.913 187.730 220.329 1.00 75.95  ? 432  SER A CA  1 
ATOM   3235  C  C   . SER A 1 432 ? 161.405 187.495 220.519 1.00 75.95  ? 432  SER A C   1 
ATOM   3236  O  O   . SER A 1 432 ? 162.122 188.372 221.012 1.00 75.95  ? 432  SER A O   1 
ATOM   3237  C  CB  . SER A 1 432 ? 159.114 187.024 221.424 1.00 75.95  ? 432  SER A CB  1 
ATOM   3238  O  OG  . SER A 1 432 ? 159.818 187.039 222.654 1.00 75.95  ? 432  SER A OG  1 
ATOM   3239  N  N   . LEU A 1 433 ? 161.893 186.317 220.125 1.00 69.73  ? 433  LEU A N   1 
ATOM   3240  C  CA  . LEU A 1 433 ? 163.321 186.036 220.224 1.00 69.73  ? 433  LEU A CA  1 
ATOM   3241  C  C   . LEU A 1 433 ? 164.127 186.926 219.285 1.00 69.73  ? 433  LEU A C   1 
ATOM   3242  O  O   . LEU A 1 433 ? 165.213 187.395 219.647 1.00 69.73  ? 433  LEU A O   1 
ATOM   3243  C  CB  . LEU A 1 433 ? 163.589 184.561 219.930 1.00 69.73  ? 433  LEU A CB  1 
ATOM   3244  C  CG  . LEU A 1 433 ? 163.289 183.579 221.063 1.00 69.73  ? 433  LEU A CG  1 
ATOM   3245  C  CD1 . LEU A 1 433 ? 163.483 182.146 220.596 1.00 69.73  ? 433  LEU A CD1 1 
ATOM   3246  C  CD2 . LEU A 1 433 ? 164.161 183.872 222.272 1.00 69.73  ? 433  LEU A CD2 1 
ATOM   3247  N  N   . ALA A 1 434 ? 163.616 187.164 218.074 1.00 75.17  ? 434  ALA A N   1 
ATOM   3248  C  CA  . ALA A 1 434 ? 164.331 188.009 217.123 1.00 75.17  ? 434  ALA A CA  1 
ATOM   3249  C  C   . ALA A 1 434 ? 164.465 189.436 217.638 1.00 75.17  ? 434  ALA A C   1 
ATOM   3250  O  O   . ALA A 1 434 ? 165.534 190.046 217.524 1.00 75.17  ? 434  ALA A O   1 
ATOM   3251  C  CB  . ALA A 1 434 ? 163.621 187.990 215.769 1.00 75.17  ? 434  ALA A CB  1 
ATOM   3252  N  N   . SER A 1 435 ? 163.392 189.986 218.209 1.00 78.45  ? 435  SER A N   1 
ATOM   3253  C  CA  . SER A 1 435 ? 163.447 191.334 218.760 1.00 78.45  ? 435  SER A CA  1 
ATOM   3254  C  C   . SER A 1 435 ? 164.096 191.378 220.136 1.00 78.45  ? 435  SER A C   1 
ATOM   3255  O  O   . SER A 1 435 ? 164.390 192.470 220.634 1.00 78.45  ? 435  SER A O   1 
ATOM   3256  C  CB  . SER A 1 435 ? 162.039 191.927 218.838 1.00 78.45  ? 435  SER A CB  1 
ATOM   3257  O  OG  . SER A 1 435 ? 161.419 191.933 217.564 1.00 78.45  ? 435  SER A OG  1 
ATOM   3258  N  N   . ARG A 1 436 ? 164.326 190.221 220.755 1.00 79.90  ? 436  ARG A N   1 
ATOM   3259  C  CA  . ARG A 1 436 ? 164.894 190.158 222.093 1.00 79.90  ? 436  ARG A CA  1 
ATOM   3260  C  C   . ARG A 1 436 ? 166.388 189.862 222.084 1.00 79.90  ? 436  ARG A C   1 
ATOM   3261  O  O   . ARG A 1 436 ? 167.083 190.219 223.042 1.00 79.90  ? 436  ARG A O   1 
ATOM   3262  C  CB  . ARG A 1 436 ? 164.154 189.090 222.910 1.00 79.90  ? 436  ARG A CB  1 
ATOM   3263  C  CG  . ARG A 1 436 ? 164.313 189.180 224.422 1.00 79.90  ? 436  ARG A CG  1 
ATOM   3264  C  CD  . ARG A 1 436 ? 165.423 188.286 224.945 1.00 79.90  ? 436  ARG A CD  1 
ATOM   3265  N  NE  . ARG A 1 436 ? 165.387 188.188 226.399 1.00 79.90  ? 436  ARG A NE  1 
ATOM   3266  C  CZ  . ARG A 1 436 ? 165.872 189.103 227.227 1.00 79.90  ? 436  ARG A CZ  1 
ATOM   3267  N  NH1 . ARG A 1 436 ? 166.413 190.223 226.778 1.00 79.90  ? 436  ARG A NH1 1 
ATOM   3268  N  NH2 . ARG A 1 436 ? 165.802 188.893 228.538 1.00 79.90  ? 436  ARG A NH2 1 
ATOM   3269  N  N   . TRP A 1 437 ? 166.896 189.236 221.025 1.00 76.30  ? 437  TRP A N   1 
ATOM   3270  C  CA  . TRP A 1 437 ? 168.295 188.854 220.920 1.00 76.30  ? 437  TRP A CA  1 
ATOM   3271  C  C   . TRP A 1 437 ? 168.911 189.481 219.675 1.00 76.30  ? 437  TRP A C   1 
ATOM   3272  O  O   . TRP A 1 437 ? 168.224 189.722 218.678 1.00 76.30  ? 437  TRP A O   1 
ATOM   3273  C  CB  . TRP A 1 437 ? 168.446 187.329 220.857 1.00 76.30  ? 437  TRP A CB  1 
ATOM   3274  C  CG  . TRP A 1 437 ? 168.094 186.631 222.132 1.00 76.30  ? 437  TRP A CG  1 
ATOM   3275  C  CD1 . TRP A 1 437 ? 166.892 186.070 222.452 1.00 76.30  ? 437  TRP A CD1 1 
ATOM   3276  C  CD2 . TRP A 1 437 ? 168.954 186.403 223.254 1.00 76.30  ? 437  TRP A CD2 1 
ATOM   3277  N  NE1 . TRP A 1 437 ? 166.948 185.515 223.707 1.00 76.30  ? 437  TRP A NE1 1 
ATOM   3278  C  CE2 . TRP A 1 437 ? 168.203 185.705 224.220 1.00 76.30  ? 437  TRP A CE2 1 
ATOM   3279  C  CE3 . TRP A 1 437 ? 170.284 186.725 223.537 1.00 76.30  ? 437  TRP A CE3 1 
ATOM   3280  C  CZ2 . TRP A 1 437 ? 168.738 185.323 225.448 1.00 76.30  ? 437  TRP A CZ2 1 
ATOM   3281  C  CZ3 . TRP A 1 437 ? 170.813 186.345 224.757 1.00 76.30  ? 437  TRP A CZ3 1 
ATOM   3282  C  CH2 . TRP A 1 437 ? 170.041 185.652 225.697 1.00 76.30  ? 437  TRP A CH2 1 
ATOM   3283  N  N   . GLN A 1 438 ? 170.214 189.744 219.742 1.00 76.75  ? 438  GLN A N   1 
ATOM   3284  C  CA  . GLN A 1 438 ? 170.959 190.287 218.616 1.00 76.75  ? 438  GLN A CA  1 
ATOM   3285  C  C   . GLN A 1 438 ? 172.278 189.543 218.463 1.00 76.75  ? 438  GLN A C   1 
ATOM   3286  O  O   . GLN A 1 438 ? 172.934 189.198 219.449 1.00 76.75  ? 438  GLN A O   1 
ATOM   3287  C  CB  . GLN A 1 438 ? 171.209 191.795 218.782 1.00 76.75  ? 438  GLN A CB  1 
ATOM   3288  C  CG  . GLN A 1 438 ? 172.129 192.159 219.934 1.00 76.75  ? 438  GLN A CG  1 
ATOM   3289  C  CD  . GLN A 1 438 ? 172.345 193.654 220.054 1.00 76.75  ? 438  GLN A CD  1 
ATOM   3290  O  OE1 . GLN A 1 438 ? 171.836 194.433 219.248 1.00 76.75  ? 438  GLN A OE1 1 
ATOM   3291  N  NE2 . GLN A 1 438 ? 173.104 194.062 221.064 1.00 76.75  ? 438  GLN A NE2 1 
ATOM   3292  N  N   . LYS A 1 439 ? 172.656 189.294 217.213 1.00 68.23  ? 439  LYS A N   1 
ATOM   3293  C  CA  . LYS A 1 439 ? 173.869 188.548 216.915 1.00 68.23  ? 439  LYS A CA  1 
ATOM   3294  C  C   . LYS A 1 439 ? 175.109 189.402 217.150 1.00 68.23  ? 439  LYS A C   1 
ATOM   3295  O  O   . LYS A 1 439 ? 175.111 190.614 216.916 1.00 68.23  ? 439  LYS A O   1 
ATOM   3296  C  CB  . LYS A 1 439 ? 173.848 188.053 215.468 1.00 68.23  ? 439  LYS A CB  1 
ATOM   3297  C  CG  . LYS A 1 439 ? 174.974 187.096 215.118 1.00 68.23  ? 439  LYS A CG  1 
ATOM   3298  C  CD  . LYS A 1 439 ? 175.163 186.986 213.616 1.00 68.23  ? 439  LYS A CD  1 
ATOM   3299  C  CE  . LYS A 1 439 ? 176.441 186.236 213.282 1.00 68.23  ? 439  LYS A CE  1 
ATOM   3300  N  NZ  . LYS A 1 439 ? 176.320 185.457 212.021 1.00 68.23  ? 439  LYS A NZ  1 
ATOM   3301  N  N   . ILE A 1 440 ? 176.176 188.752 217.617 1.00 68.32  ? 440  ILE A N   1 
ATOM   3302  C  CA  . ILE A 1 440 ? 177.480 189.381 217.789 1.00 68.32  ? 440  ILE A CA  1 
ATOM   3303  C  C   . ILE A 1 440 ? 178.551 188.680 216.963 1.00 68.32  ? 440  ILE A C   1 
ATOM   3304  O  O   . ILE A 1 440 ? 179.199 189.299 216.113 1.00 68.32  ? 440  ILE A O   1 
ATOM   3305  C  CB  . ILE A 1 440 ? 177.891 189.437 219.276 1.00 68.32  ? 440  ILE A CB  1 
ATOM   3306  C  CG1 . ILE A 1 440 ? 177.010 190.421 220.041 1.00 68.32  ? 440  ILE A CG1 1 
ATOM   3307  C  CG2 . ILE A 1 440 ? 179.357 189.816 219.411 1.00 68.32  ? 440  ILE A CG2 1 
ATOM   3308  C  CD1 . ILE A 1 440 ? 177.276 190.423 221.520 1.00 68.32  ? 440  ILE A CD1 1 
ATOM   3309  N  N   . ASP A 1 441 ? 178.756 187.386 217.201 1.00 69.16  ? 441  ASP A N   1 
ATOM   3310  C  CA  . ASP A 1 441 ? 179.835 186.671 216.535 1.00 69.16  ? 441  ASP A CA  1 
ATOM   3311  C  C   . ASP A 1 441 ? 179.364 185.275 216.154 1.00 69.16  ? 441  ASP A C   1 
ATOM   3312  O  O   . ASP A 1 441 ? 178.326 184.799 216.615 1.00 69.16  ? 441  ASP A O   1 
ATOM   3313  C  CB  . ASP A 1 441 ? 181.086 186.601 217.417 1.00 69.16  ? 441  ASP A CB  1 
ATOM   3314  C  CG  . ASP A 1 441 ? 182.370 186.596 216.609 1.00 69.16  ? 441  ASP A CG  1 
ATOM   3315  O  OD1 . ASP A 1 441 ? 182.383 187.186 215.508 1.00 69.16  ? 441  ASP A OD1 1 
ATOM   3316  O  OD2 . ASP A 1 441 ? 183.366 186.004 217.075 1.00 69.16  ? 441  ASP A OD2 1 
ATOM   3317  N  N   . GLU A 1 442 ? 180.150 184.617 215.306 1.00 63.87  ? 442  GLU A N   1 
ATOM   3318  C  CA  . GLU A 1 442 ? 179.823 183.278 214.836 1.00 63.87  ? 442  GLU A CA  1 
ATOM   3319  C  C   . GLU A 1 442 ? 181.098 182.467 214.667 1.00 63.87  ? 442  GLU A C   1 
ATOM   3320  O  O   . GLU A 1 442 ? 182.071 182.950 214.081 1.00 63.87  ? 442  GLU A O   1 
ATOM   3321  C  CB  . GLU A 1 442 ? 179.053 183.335 213.513 1.00 63.87  ? 442  GLU A CB  1 
ATOM   3322  C  CG  . GLU A 1 442 ? 178.512 181.996 213.048 1.00 63.87  ? 442  GLU A CG  1 
ATOM   3323  C  CD  . GLU A 1 442 ? 177.906 182.070 211.663 1.00 63.87  ? 442  GLU A CD  1 
ATOM   3324  O  OE1 . GLU A 1 442 ? 177.616 183.194 211.203 1.00 63.87  ? 442  GLU A OE1 1 
ATOM   3325  O  OE2 . GLU A 1 442 ? 177.718 181.008 211.035 1.00 63.87  ? 442  GLU A OE2 1 
ATOM   3326  N  N   . ILE A 1 443 ? 181.087 181.242 215.181 1.00 63.09  ? 443  ILE A N   1 
ATOM   3327  C  CA  . ILE A 1 443 ? 182.189 180.300 215.018 1.00 63.09  ? 443  ILE A CA  1 
ATOM   3328  C  C   . ILE A 1 443 ? 181.706 179.208 214.071 1.00 63.09  ? 443  ILE A C   1 
ATOM   3329  O  O   . ILE A 1 443 ? 180.878 178.366 214.461 1.00 63.09  ? 443  ILE A O   1 
ATOM   3330  C  CB  . ILE A 1 443 ? 182.644 179.729 216.369 1.00 63.09  ? 443  ILE A CB  1 
ATOM   3331  C  CG1 . ILE A 1 443 ? 182.737 180.846 217.408 1.00 63.09  ? 443  ILE A CG1 1 
ATOM   3332  C  CG2 . ILE A 1 443 ? 183.996 179.061 216.233 1.00 63.09  ? 443  ILE A CG2 1 
ATOM   3333  C  CD1 . ILE A 1 443 ? 182.851 180.347 218.830 1.00 63.09  ? 443  ILE A CD1 1 
ATOM   3334  N  N   . PRO A 1 444 ? 182.185 179.191 212.822 1.00 59.19  ? 444  PRO A N   1 
ATOM   3335  C  CA  . PRO A 1 444 ? 181.590 178.319 211.799 1.00 59.19  ? 444  PRO A CA  1 
ATOM   3336  C  C   . PRO A 1 444 ? 181.855 176.839 212.016 1.00 59.19  ? 444  PRO A C   1 
ATOM   3337  O  O   . PRO A 1 444 ? 182.471 176.437 213.007 1.00 59.19  ? 444  PRO A O   1 
ATOM   3338  C  CB  . PRO A 1 444 ? 182.247 178.808 210.501 1.00 59.19  ? 444  PRO A CB  1 
ATOM   3339  C  CG  . PRO A 1 444 ? 182.746 180.185 210.818 1.00 59.19  ? 444  PRO A CG  1 
ATOM   3340  C  CD  . PRO A 1 444 ? 183.180 180.106 212.244 1.00 59.19  ? 444  PRO A CD  1 
ATOM   3341  N  N   . PHE A 1 445 ? 181.388 176.023 211.076 1.00 64.58  ? 445  PHE A N   1 
ATOM   3342  C  CA  . PHE A 1 445 ? 181.511 174.578 211.180 1.00 64.58  ? 445  PHE A CA  1 
ATOM   3343  C  C   . PHE A 1 445 ? 182.807 174.100 210.538 1.00 64.58  ? 445  PHE A C   1 
ATOM   3344  O  O   . PHE A 1 445 ? 183.161 174.516 209.431 1.00 64.58  ? 445  PHE A O   1 
ATOM   3345  C  CB  . PHE A 1 445 ? 180.310 173.903 210.515 1.00 64.58  ? 445  PHE A CB  1 
ATOM   3346  C  CG  . PHE A 1 445 ? 180.339 172.403 210.575 1.00 64.58  ? 445  PHE A CG  1 
ATOM   3347  C  CD1 . PHE A 1 445 ? 179.780 171.730 211.647 1.00 64.58  ? 445  PHE A CD1 1 
ATOM   3348  C  CD2 . PHE A 1 445 ? 180.902 171.664 209.548 1.00 64.58  ? 445  PHE A CD2 1 
ATOM   3349  C  CE1 . PHE A 1 445 ? 179.797 170.351 211.702 1.00 64.58  ? 445  PHE A CE1 1 
ATOM   3350  C  CE2 . PHE A 1 445 ? 180.923 170.285 209.598 1.00 64.58  ? 445  PHE A CE2 1 
ATOM   3351  C  CZ  . PHE A 1 445 ? 180.369 169.628 210.676 1.00 64.58  ? 445  PHE A CZ  1 
ATOM   3352  N  N   . ASP A 1 446 ? 183.515 173.222 211.245 1.00 68.48  ? 446  ASP A N   1 
ATOM   3353  C  CA  . ASP A 1 446 ? 184.717 172.585 210.730 1.00 68.48  ? 446  ASP A CA  1 
ATOM   3354  C  C   . ASP A 1 446 ? 184.804 171.176 211.295 1.00 68.48  ? 446  ASP A C   1 
ATOM   3355  O  O   . ASP A 1 446 ? 184.292 170.888 212.379 1.00 68.48  ? 446  ASP A O   1 
ATOM   3356  C  CB  . ASP A 1 446 ? 185.978 173.387 211.075 1.00 68.48  ? 446  ASP A CB  1 
ATOM   3357  C  CG  . ASP A 1 446 ? 186.012 173.815 212.524 1.00 68.48  ? 446  ASP A CG  1 
ATOM   3358  O  OD1 . ASP A 1 446 ? 184.968 173.704 213.197 1.00 68.48  ? 446  ASP A OD1 1 
ATOM   3359  O  OD2 . ASP A 1 446 ? 187.081 174.262 212.988 1.00 68.48  ? 446  ASP A OD2 1 
ATOM   3360  N  N   . PHE A 1 447 ? 185.472 170.296 210.550 1.00 70.93  ? 447  PHE A N   1 
ATOM   3361  C  CA  . PHE A 1 447 ? 185.457 168.872 210.864 1.00 70.93  ? 447  PHE A CA  1 
ATOM   3362  C  C   . PHE A 1 447 ? 186.388 168.482 212.004 1.00 70.93  ? 447  PHE A C   1 
ATOM   3363  O  O   . PHE A 1 447 ? 186.277 167.359 212.506 1.00 70.93  ? 447  PHE A O   1 
ATOM   3364  C  CB  . PHE A 1 447 ? 185.803 168.060 209.616 1.00 70.93  ? 447  PHE A CB  1 
ATOM   3365  C  CG  . PHE A 1 447 ? 184.676 167.966 208.632 1.00 70.93  ? 447  PHE A CG  1 
ATOM   3366  C  CD1 . PHE A 1 447 ? 183.767 166.923 208.700 1.00 70.93  ? 447  PHE A CD1 1 
ATOM   3367  C  CD2 . PHE A 1 447 ? 184.513 168.928 207.650 1.00 70.93  ? 447  PHE A CD2 1 
ATOM   3368  C  CE1 . PHE A 1 447 ? 182.723 166.834 207.800 1.00 70.93  ? 447  PHE A CE1 1 
ATOM   3369  C  CE2 . PHE A 1 447 ? 183.470 168.845 206.749 1.00 70.93  ? 447  PHE A CE2 1 
ATOM   3370  C  CZ  . PHE A 1 447 ? 182.575 167.797 206.823 1.00 70.93  ? 447  PHE A CZ  1 
ATOM   3371  N  N   . GLU A 1 448 ? 187.297 169.362 212.427 1.00 76.22  ? 448  GLU A N   1 
ATOM   3372  C  CA  . GLU A 1 448 ? 188.138 169.032 213.573 1.00 76.22  ? 448  GLU A CA  1 
ATOM   3373  C  C   . GLU A 1 448 ? 187.328 168.959 214.861 1.00 76.22  ? 448  GLU A C   1 
ATOM   3374  O  O   . GLU A 1 448 ? 187.673 168.190 215.766 1.00 76.22  ? 448  GLU A O   1 
ATOM   3375  C  CB  . GLU A 1 448 ? 189.275 170.042 213.713 1.00 76.22  ? 448  GLU A CB  1 
ATOM   3376  C  CG  . GLU A 1 448 ? 190.465 169.755 212.811 1.00 76.22  ? 448  GLU A CG  1 
ATOM   3377  C  CD  . GLU A 1 448 ? 191.719 170.489 213.245 1.00 76.22  ? 448  GLU A CD  1 
ATOM   3378  O  OE1 . GLU A 1 448 ? 191.898 170.694 214.463 1.00 76.22  ? 448  GLU A OE1 1 
ATOM   3379  O  OE2 . GLU A 1 448 ? 192.534 170.847 212.369 1.00 76.22  ? 448  GLU A OE2 1 
ATOM   3380  N  N   . ARG A 1 449 ? 186.256 169.740 214.965 1.00 65.20  ? 449  ARG A N   1 
ATOM   3381  C  CA  . ARG A 1 449 ? 185.400 169.734 216.143 1.00 65.20  ? 449  ARG A CA  1 
ATOM   3382  C  C   . ARG A 1 449 ? 183.941 169.439 215.837 1.00 65.20  ? 449  ARG A C   1 
ATOM   3383  O  O   . ARG A 1 449 ? 183.207 169.051 216.748 1.00 65.20  ? 449  ARG A O   1 
ATOM   3384  C  CB  . ARG A 1 449 ? 185.484 171.082 216.873 1.00 65.20  ? 449  ARG A CB  1 
ATOM   3385  C  CG  . ARG A 1 449 ? 184.993 172.242 216.038 1.00 65.20  ? 449  ARG A CG  1 
ATOM   3386  C  CD  . ARG A 1 449 ? 185.719 173.532 216.368 1.00 65.20  ? 449  ARG A CD  1 
ATOM   3387  N  NE  . ARG A 1 449 ? 185.190 174.645 215.591 1.00 65.20  ? 449  ARG A NE  1 
ATOM   3388  C  CZ  . ARG A 1 449 ? 183.991 175.183 215.768 1.00 65.20  ? 449  ARG A CZ  1 
ATOM   3389  N  NH1 . ARG A 1 449 ? 183.183 174.773 216.732 1.00 65.20  ? 449  ARG A NH1 1 
ATOM   3390  N  NH2 . ARG A 1 449 ? 183.591 176.156 214.956 1.00 65.20  ? 449  ARG A NH2 1 
ATOM   3391  N  N   . ARG A 1 450 ? 183.500 169.629 214.593 1.00 62.58  ? 450  ARG A N   1 
ATOM   3392  C  CA  . ARG A 1 450 ? 182.147 169.310 214.143 1.00 62.58  ? 450  ARG A CA  1 
ATOM   3393  C  C   . ARG A 1 450 ? 181.065 170.001 214.966 1.00 62.58  ? 450  ARG A C   1 
ATOM   3394  O  O   . ARG A 1 450 ? 180.002 169.421 215.205 1.00 62.58  ? 450  ARG A O   1 
ATOM   3395  C  CB  . ARG A 1 450 ? 181.917 167.794 214.128 1.00 62.58  ? 450  ARG A CB  1 
ATOM   3396  C  CG  . ARG A 1 450 ? 182.849 167.056 213.178 1.00 62.58  ? 450  ARG A CG  1 
ATOM   3397  C  CD  . ARG A 1 450 ? 183.181 165.661 213.676 1.00 62.58  ? 450  ARG A CD  1 
ATOM   3398  N  NE  . ARG A 1 450 ? 182.027 164.772 213.630 1.00 62.58  ? 450  ARG A NE  1 
ATOM   3399  C  CZ  . ARG A 1 450 ? 181.951 163.685 212.874 1.00 62.58  ? 450  ARG A CZ  1 
ATOM   3400  N  NH1 . ARG A 1 450 ? 182.948 163.323 212.082 1.00 62.58  ? 450  ARG A NH1 1 
ATOM   3401  N  NH2 . ARG A 1 450 ? 180.848 162.943 212.913 1.00 62.58  ? 450  ARG A NH2 1 
ATOM   3402  N  N   . ARG A 1 451 ? 181.313 171.232 215.405 1.00 59.50  ? 451  ARG A N   1 
ATOM   3403  C  CA  . ARG A 1 451 ? 180.357 172.010 216.179 1.00 59.50  ? 451  ARG A CA  1 
ATOM   3404  C  C   . ARG A 1 451 ? 180.236 173.403 215.579 1.00 59.50  ? 451  ARG A C   1 
ATOM   3405  O  O   . ARG A 1 451 ? 181.231 173.979 215.128 1.00 59.50  ? 451  ARG A O   1 
ATOM   3406  C  CB  . ARG A 1 451 ? 180.791 172.119 217.643 1.00 59.50  ? 451  ARG A CB  1 
ATOM   3407  C  CG  . ARG A 1 451 ? 180.851 170.798 218.384 1.00 59.50  ? 451  ARG A CG  1 
ATOM   3408  C  CD  . ARG A 1 451 ? 181.142 171.022 219.858 1.00 59.50  ? 451  ARG A CD  1 
ATOM   3409  N  NE  . ARG A 1 451 ? 182.430 171.675 220.066 1.00 59.50  ? 451  ARG A NE  1 
ATOM   3410  C  CZ  . ARG A 1 451 ? 183.585 171.035 220.181 1.00 59.50  ? 451  ARG A CZ  1 
ATOM   3411  N  NH1 . ARG A 1 451 ? 183.653 169.715 220.119 1.00 59.50  ? 451  ARG A NH1 1 
ATOM   3412  N  NH2 . ARG A 1 451 ? 184.700 171.736 220.365 1.00 59.50  ? 451  ARG A NH2 1 
ATOM   3413  N  N   . MET A 1 452 ? 179.024 173.946 215.570 1.00 57.07  ? 452  MET A N   1 
ATOM   3414  C  CA  . MET A 1 452 ? 178.814 175.316 215.126 1.00 57.07  ? 452  MET A CA  1 
ATOM   3415  C  C   . MET A 1 452 ? 178.330 176.167 216.293 1.00 57.07  ? 452  MET A C   1 
ATOM   3416  O  O   . MET A 1 452 ? 177.548 175.715 217.131 1.00 57.07  ? 452  MET A O   1 
ATOM   3417  C  CB  . MET A 1 452 ? 177.805 175.366 213.976 1.00 57.07  ? 452  MET A CB  1 
ATOM   3418  C  CG  . MET A 1 452 ? 177.546 176.760 213.435 1.00 57.07  ? 452  MET A CG  1 
ATOM   3419  S  SD  . MET A 1 452 ? 176.224 176.799 212.213 1.00 57.07  ? 452  MET A SD  1 
ATOM   3420  C  CE  . MET A 1 452 ? 176.284 175.124 211.578 1.00 57.07  ? 452  MET A CE  1 
ATOM   3421  N  N   . SER A 1 453 ? 178.798 177.414 216.346 1.00 59.61  ? 453  SER A N   1 
ATOM   3422  C  CA  . SER A 1 453 ? 178.458 178.256 217.483 1.00 59.61  ? 453  SER A CA  1 
ATOM   3423  C  C   . SER A 1 453 ? 178.066 179.646 217.009 1.00 59.61  ? 453  SER A C   1 
ATOM   3424  O  O   . SER A 1 453 ? 178.575 180.141 216.002 1.00 59.61  ? 453  SER A O   1 
ATOM   3425  C  CB  . SER A 1 453 ? 179.622 178.349 218.476 1.00 59.61  ? 453  SER A CB  1 
ATOM   3426  O  OG  . SER A 1 453 ? 180.185 177.073 218.721 1.00 59.61  ? 453  SER A OG  1 
ATOM   3427  N  N   . VAL A 1 454 ? 177.158 180.271 217.752 1.00 59.29  ? 454  VAL A N   1 
ATOM   3428  C  CA  . VAL A 1 454 ? 176.773 181.659 217.530 1.00 59.29  ? 454  VAL A CA  1 
ATOM   3429  C  C   . VAL A 1 454 ? 176.723 182.353 218.883 1.00 59.29  ? 454  VAL A C   1 
ATOM   3430  O  O   . VAL A 1 454 ? 176.089 181.854 219.818 1.00 59.29  ? 454  VAL A O   1 
ATOM   3431  C  CB  . VAL A 1 454 ? 175.416 181.774 216.807 1.00 59.29  ? 454  VAL A CB  1 
ATOM   3432  C  CG1 . VAL A 1 454 ? 174.876 183.187 216.910 1.00 59.29  ? 454  VAL A CG1 1 
ATOM   3433  C  CG2 . VAL A 1 454 ? 175.554 181.362 215.350 1.00 59.29  ? 454  VAL A CG2 1 
ATOM   3434  N  N   . VAL A 1 455 ? 177.398 183.492 218.996 1.00 66.22  ? 455  VAL A N   1 
ATOM   3435  C  CA  . VAL A 1 455 ? 177.417 184.275 220.224 1.00 66.22  ? 455  VAL A CA  1 
ATOM   3436  C  C   . VAL A 1 455 ? 176.524 185.488 220.017 1.00 66.22  ? 455  VAL A C   1 
ATOM   3437  O  O   . VAL A 1 455 ? 176.822 186.354 219.184 1.00 66.22  ? 455  VAL A O   1 
ATOM   3438  C  CB  . VAL A 1 455 ? 178.843 184.699 220.602 1.00 66.22  ? 455  VAL A CB  1 
ATOM   3439  C  CG1 . VAL A 1 455 ? 178.838 185.399 221.948 1.00 66.22  ? 455  VAL A CG1 1 
ATOM   3440  C  CG2 . VAL A 1 455 ? 179.767 183.497 220.618 1.00 66.22  ? 455  VAL A CG2 1 
ATOM   3441  N  N   . VAL A 1 456 ? 175.435 185.545 220.781 1.00 70.53  ? 456  VAL A N   1 
ATOM   3442  C  CA  . VAL A 1 456 ? 174.463 186.624 220.720 1.00 70.53  ? 456  VAL A CA  1 
ATOM   3443  C  C   . VAL A 1 456 ? 174.442 187.321 222.075 1.00 70.53  ? 456  VAL A C   1 
ATOM   3444  O  O   . VAL A 1 456 ? 175.179 186.964 222.992 1.00 70.53  ? 456  VAL A O   1 
ATOM   3445  C  CB  . VAL A 1 456 ? 173.058 186.123 220.342 1.00 70.53  ? 456  VAL A CB  1 
ATOM   3446  C  CG1 . VAL A 1 456 ? 173.055 185.576 218.929 1.00 70.53  ? 456  VAL A CG1 1 
ATOM   3447  C  CG2 . VAL A 1 456 ? 172.597 185.062 221.326 1.00 70.53  ? 456  VAL A CG2 1 
ATOM   3448  N  N   . ALA A 1 457 ? 173.587 188.335 222.191 1.00 80.51  ? 457  ALA A N   1 
ATOM   3449  C  CA  . ALA A 1 457 ? 173.437 189.037 223.456 1.00 80.51  ? 457  ALA A CA  1 
ATOM   3450  C  C   . ALA A 1 457 ? 172.036 189.614 223.566 1.00 80.51  ? 457  ALA A C   1 
ATOM   3451  O  O   . ALA A 1 457 ? 171.479 190.110 222.583 1.00 80.51  ? 457  ALA A O   1 
ATOM   3452  C  CB  . ALA A 1 457 ? 174.470 190.156 223.607 1.00 80.51  ? 457  ALA A CB  1 
ATOM   3453  N  N   . GLU A 1 458 ? 171.478 189.544 224.771 1.00 87.19  ? 458  GLU A N   1 
ATOM   3454  C  CA  . GLU A 1 458 ? 170.219 190.199 225.087 1.00 87.19  ? 458  GLU A CA  1 
ATOM   3455  C  C   . GLU A 1 458 ? 170.412 191.620 225.596 1.00 87.19  ? 458  GLU A C   1 
ATOM   3456  O  O   . GLU A 1 458 ? 169.433 192.368 225.689 1.00 87.19  ? 458  GLU A O   1 
ATOM   3457  C  CB  . GLU A 1 458 ? 169.450 189.384 226.131 1.00 87.19  ? 458  GLU A CB  1 
ATOM   3458  C  CG  . GLU A 1 458 ? 170.154 189.285 227.474 1.00 87.19  ? 458  GLU A CG  1 
ATOM   3459  C  CD  . GLU A 1 458 ? 169.465 188.325 228.423 1.00 87.19  ? 458  GLU A CD  1 
ATOM   3460  O  OE1 . GLU A 1 458 ? 168.537 187.614 227.983 1.00 87.19  ? 458  GLU A OE1 1 
ATOM   3461  O  OE2 . GLU A 1 458 ? 169.851 188.282 229.610 1.00 87.19  ? 458  GLU A OE2 1 
ATOM   3462  N  N   . ASN A 1 459 ? 171.642 192.002 225.921 1.00 93.94  ? 459  ASN A N   1 
ATOM   3463  C  CA  . ASN A 1 459 ? 171.960 193.331 226.425 1.00 93.94  ? 459  ASN A CA  1 
ATOM   3464  C  C   . ASN A 1 459 ? 173.440 193.588 226.166 1.00 93.94  ? 459  ASN A C   1 
ATOM   3465  O  O   . ASN A 1 459 ? 174.094 192.847 225.424 1.00 93.94  ? 459  ASN A O   1 
ATOM   3466  C  CB  . ASN A 1 459 ? 171.596 193.453 227.910 1.00 93.94  ? 459  ASN A CB  1 
ATOM   3467  C  CG  . ASN A 1 459 ? 172.163 192.320 228.747 1.00 93.94  ? 459  ASN A CG  1 
ATOM   3468  O  OD1 . ASN A 1 459 ? 173.357 192.023 228.691 1.00 93.94  ? 459  ASN A OD1 1 
ATOM   3469  N  ND2 . ASN A 1 459 ? 171.305 191.681 229.532 1.00 93.94  ? 459  ASN A ND2 1 
ATOM   3470  N  N   . THR A 1 460 ? 173.973 194.642 226.779 1.00 100.03 ? 460  THR A N   1 
ATOM   3471  C  CA  . THR A 1 460 ? 175.383 194.984 226.662 1.00 100.03 ? 460  THR A CA  1 
ATOM   3472  C  C   . THR A 1 460 ? 176.206 194.496 227.848 1.00 100.03 ? 460  THR A C   1 
ATOM   3473  O  O   . THR A 1 460 ? 177.397 194.810 227.934 1.00 100.03 ? 460  THR A O   1 
ATOM   3474  C  CB  . THR A 1 460 ? 175.551 196.496 226.501 1.00 100.03 ? 460  THR A CB  1 
ATOM   3475  O  OG1 . THR A 1 460 ? 176.946 196.820 226.437 1.00 100.03 ? 460  THR A OG1 1 
ATOM   3476  C  CG2 . THR A 1 460 ? 174.916 197.231 227.671 1.00 100.03 ? 460  THR A CG2 1 
ATOM   3477  N  N   . GLU A 1 461 ? 175.601 193.738 228.762 1.00 96.39  ? 461  GLU A N   1 
ATOM   3478  C  CA  . GLU A 1 461 ? 176.282 193.260 229.960 1.00 96.39  ? 461  GLU A CA  1 
ATOM   3479  C  C   . GLU A 1 461 ? 176.899 191.879 229.777 1.00 96.39  ? 461  GLU A C   1 
ATOM   3480  O  O   . GLU A 1 461 ? 178.078 191.682 230.084 1.00 96.39  ? 461  GLU A O   1 
ATOM   3481  C  CB  . GLU A 1 461 ? 175.309 193.241 231.144 1.00 96.39  ? 461  GLU A CB  1 
ATOM   3482  C  CG  . GLU A 1 461 ? 174.782 194.611 231.533 1.00 96.39  ? 461  GLU A CG  1 
ATOM   3483  C  CD  . GLU A 1 461 ? 175.873 195.662 231.578 1.00 96.39  ? 461  GLU A CD  1 
ATOM   3484  O  OE1 . GLU A 1 461 ? 176.803 195.521 232.400 1.00 96.39  ? 461  GLU A OE1 1 
ATOM   3485  O  OE2 . GLU A 1 461 ? 175.801 196.630 230.793 1.00 96.39  ? 461  GLU A OE2 1 
ATOM   3486  N  N   . HIS A 1 462 ? 176.125 190.915 229.285 1.00 87.86  ? 462  HIS A N   1 
ATOM   3487  C  CA  . HIS A 1 462 ? 176.592 189.547 229.123 1.00 87.86  ? 462  HIS A CA  1 
ATOM   3488  C  C   . HIS A 1 462 ? 176.209 189.027 227.747 1.00 87.86  ? 462  HIS A C   1 
ATOM   3489  O  O   . HIS A 1 462 ? 175.231 189.478 227.144 1.00 87.86  ? 462  HIS A O   1 
ATOM   3490  C  CB  . HIS A 1 462 ? 176.013 188.623 230.203 1.00 87.86  ? 462  HIS A CB  1 
ATOM   3491  C  CG  . HIS A 1 462 ? 176.386 189.017 231.597 1.00 87.86  ? 462  HIS A CG  1 
ATOM   3492  N  ND1 . HIS A 1 462 ? 175.690 189.966 232.314 1.00 87.86  ? 462  HIS A ND1 1 
ATOM   3493  C  CD2 . HIS A 1 462 ? 177.384 188.591 232.407 1.00 87.86  ? 462  HIS A CD2 1 
ATOM   3494  C  CE1 . HIS A 1 462 ? 176.242 190.107 233.506 1.00 87.86  ? 462  HIS A CE1 1 
ATOM   3495  N  NE2 . HIS A 1 462 ? 177.272 189.284 233.588 1.00 87.86  ? 462  HIS A NE2 1 
ATOM   3496  N  N   . HIS A 1 463 ? 176.992 188.072 227.256 1.00 80.08  ? 463  HIS A N   1 
ATOM   3497  C  CA  . HIS A 1 463 ? 176.740 187.424 225.981 1.00 80.08  ? 463  HIS A CA  1 
ATOM   3498  C  C   . HIS A 1 463 ? 176.464 185.944 226.205 1.00 80.08  ? 463  HIS A C   1 
ATOM   3499  O  O   . HIS A 1 463 ? 176.967 185.337 227.156 1.00 80.08  ? 463  HIS A O   1 
ATOM   3500  C  CB  . HIS A 1 463 ? 177.923 187.593 225.019 1.00 80.08  ? 463  HIS A CB  1 
ATOM   3501  C  CG  . HIS A 1 463 ? 178.321 189.018 224.792 1.00 80.08  ? 463  HIS A CG  1 
ATOM   3502  N  ND1 . HIS A 1 463 ? 179.550 189.374 224.282 1.00 80.08  ? 463  HIS A ND1 1 
ATOM   3503  C  CD2 . HIS A 1 463 ? 177.652 190.176 225.005 1.00 80.08  ? 463  HIS A CD2 1 
ATOM   3504  C  CE1 . HIS A 1 463 ? 179.622 190.690 224.190 1.00 80.08  ? 463  HIS A CE1 1 
ATOM   3505  N  NE2 . HIS A 1 463 ? 178.484 191.201 224.623 1.00 80.08  ? 463  HIS A NE2 1 
ATOM   3506  N  N   . GLN A 1 464 ? 175.641 185.374 225.333 1.00 69.22  ? 464  GLN A N   1 
ATOM   3507  C  CA  . GLN A 1 464 ? 175.303 183.959 225.374 1.00 69.22  ? 464  GLN A CA  1 
ATOM   3508  C  C   . GLN A 1 464 ? 175.855 183.282 224.127 1.00 69.22  ? 464  GLN A C   1 
ATOM   3509  O  O   . GLN A 1 464 ? 175.526 183.675 223.003 1.00 69.22  ? 464  GLN A O   1 
ATOM   3510  C  CB  . GLN A 1 464 ? 173.792 183.756 225.473 1.00 69.22  ? 464  GLN A CB  1 
ATOM   3511  C  CG  . GLN A 1 464 ? 173.357 182.309 225.323 1.00 69.22  ? 464  GLN A CG  1 
ATOM   3512  C  CD  . GLN A 1 464 ? 171.968 182.057 225.873 1.00 69.22  ? 464  GLN A CD  1 
ATOM   3513  O  OE1 . GLN A 1 464 ? 171.373 182.925 226.511 1.00 69.22  ? 464  GLN A OE1 1 
ATOM   3514  N  NE2 . GLN A 1 464 ? 171.444 180.861 225.631 1.00 69.22  ? 464  GLN A NE2 1 
ATOM   3515  N  N   . LEU A 1 465 ? 176.696 182.274 224.332 1.00 60.63  ? 465  LEU A N   1 
ATOM   3516  C  CA  . LEU A 1 465 ? 177.201 181.430 223.260 1.00 60.63  ? 465  LEU A CA  1 
ATOM   3517  C  C   . LEU A 1 465 ? 176.312 180.199 223.166 1.00 60.63  ? 465  LEU A C   1 
ATOM   3518  O  O   . LEU A 1 465 ? 176.191 179.445 224.138 1.00 60.63  ? 465  LEU A O   1 
ATOM   3519  C  CB  . LEU A 1 465 ? 178.655 181.034 223.520 1.00 60.63  ? 465  LEU A CB  1 
ATOM   3520  C  CG  . LEU A 1 465 ? 179.326 180.039 222.569 1.00 60.63  ? 465  LEU A CG  1 
ATOM   3521  C  CD1 . LEU A 1 465 ? 180.754 180.462 222.272 1.00 60.63  ? 465  LEU A CD1 1 
ATOM   3522  C  CD2 . LEU A 1 465 ? 179.307 178.635 223.152 1.00 60.63  ? 465  LEU A CD2 1 
ATOM   3523  N  N   . VAL A 1 466 ? 175.685 180.002 222.010 1.00 55.21  ? 466  VAL A N   1 
ATOM   3524  C  CA  . VAL A 1 466 ? 174.825 178.854 221.758 1.00 55.21  ? 466  VAL A CA  1 
ATOM   3525  C  C   . VAL A 1 466 ? 175.487 178.037 220.660 1.00 55.21  ? 466  VAL A C   1 
ATOM   3526  O  O   . VAL A 1 466 ? 175.697 178.535 219.547 1.00 55.21  ? 466  VAL A O   1 
ATOM   3527  C  CB  . VAL A 1 466 ? 173.405 179.273 221.353 1.00 55.21  ? 466  VAL A CB  1 
ATOM   3528  C  CG1 . VAL A 1 466 ? 172.561 178.049 221.037 1.00 55.21  ? 466  VAL A CG1 1 
ATOM   3529  C  CG2 . VAL A 1 466 ? 172.764 180.108 222.450 1.00 55.21  ? 466  VAL A CG2 1 
ATOM   3530  N  N   . CYS A 1 467 ? 175.818 176.788 220.965 1.00 52.67  ? 467  CYS A N   1 
ATOM   3531  C  CA  . CYS A 1 467 ? 176.472 175.899 220.019 1.00 52.67  ? 467  CYS A CA  1 
ATOM   3532  C  C   . CYS A 1 467 ? 175.629 174.649 219.821 1.00 52.67  ? 467  CYS A C   1 
ATOM   3533  O  O   . CYS A 1 467 ? 174.865 174.255 220.706 1.00 52.67  ? 467  CYS A O   1 
ATOM   3534  C  CB  . CYS A 1 467 ? 177.874 175.516 220.499 1.00 52.67  ? 467  CYS A CB  1 
ATOM   3535  S  SG  . CYS A 1 467 ? 177.903 174.180 221.709 1.00 52.67  ? 467  CYS A SG  1 
ATOM   3536  N  N   . LYS A 1 468 ? 175.756 174.042 218.646 1.00 49.24  ? 468  LYS A N   1 
ATOM   3537  C  CA  . LYS A 1 468 ? 175.038 172.818 218.333 1.00 49.24  ? 468  LYS A CA  1 
ATOM   3538  C  C   . LYS A 1 468 ? 175.913 171.917 217.476 1.00 49.24  ? 468  LYS A C   1 
ATOM   3539  O  O   . LYS A 1 468 ? 176.797 172.392 216.752 1.00 49.24  ? 468  LYS A O   1 
ATOM   3540  C  CB  . LYS A 1 468 ? 173.709 173.116 217.623 1.00 49.24  ? 468  LYS A CB  1 
ATOM   3541  C  CG  . LYS A 1 468 ? 173.818 173.349 216.128 1.00 49.24  ? 468  LYS A CG  1 
ATOM   3542  C  CD  . LYS A 1 468 ? 172.483 173.792 215.550 1.00 49.24  ? 468  LYS A CD  1 
ATOM   3543  C  CE  . LYS A 1 468 ? 172.422 173.552 214.052 1.00 49.24  ? 468  LYS A CE  1 
ATOM   3544  N  NZ  . LYS A 1 468 ? 173.655 174.021 213.365 1.00 49.24  ? 468  LYS A NZ  1 
ATOM   3545  N  N   . GLY A 1 469 ? 175.664 170.616 217.568 1.00 45.99  ? 469  GLY A N   1 
ATOM   3546  C  CA  . GLY A 1 469 ? 176.430 169.676 216.769 1.00 45.99  ? 469  GLY A CA  1 
ATOM   3547  C  C   . GLY A 1 469 ? 176.134 168.248 217.165 1.00 45.99  ? 469  GLY A C   1 
ATOM   3548  O  O   . GLY A 1 469 ? 175.177 167.961 217.887 1.00 45.99  ? 469  GLY A O   1 
ATOM   3549  N  N   . ALA A 1 470 ? 176.978 167.345 216.669 1.00 51.25  ? 470  ALA A N   1 
ATOM   3550  C  CA  . ALA A 1 470 ? 176.831 165.933 216.993 1.00 51.25  ? 470  ALA A CA  1 
ATOM   3551  C  C   . ALA A 1 470 ? 176.944 165.723 218.498 1.00 51.25  ? 470  ALA A C   1 
ATOM   3552  O  O   . ALA A 1 470 ? 177.587 166.500 219.207 1.00 51.25  ? 470  ALA A O   1 
ATOM   3553  C  CB  . ALA A 1 470 ? 177.884 165.103 216.257 1.00 51.25  ? 470  ALA A CB  1 
ATOM   3554  N  N   . LEU A 1 471 ? 176.302 164.658 218.984 1.00 48.36  ? 471  LEU A N   1 
ATOM   3555  C  CA  . LEU A 1 471 ? 176.169 164.461 220.425 1.00 48.36  ? 471  LEU A CA  1 
ATOM   3556  C  C   . LEU A 1 471 ? 177.526 164.331 221.106 1.00 48.36  ? 471  LEU A C   1 
ATOM   3557  O  O   . LEU A 1 471 ? 177.781 164.974 222.131 1.00 48.36  ? 471  LEU A O   1 
ATOM   3558  C  CB  . LEU A 1 471 ? 175.322 163.223 220.712 1.00 48.36  ? 471  LEU A CB  1 
ATOM   3559  C  CG  . LEU A 1 471 ? 175.210 162.924 222.207 1.00 48.36  ? 471  LEU A CG  1 
ATOM   3560  C  CD1 . LEU A 1 471 ? 174.133 163.780 222.859 1.00 48.36  ? 471  LEU A CD1 1 
ATOM   3561  C  CD2 . LEU A 1 471 ? 174.977 161.450 222.458 1.00 48.36  ? 471  LEU A CD2 1 
ATOM   3562  N  N   . GLN A 1 472 ? 178.407 163.490 220.559 1.00 56.85  ? 472  GLN A N   1 
ATOM   3563  C  CA  . GLN A 1 472 ? 179.678 163.220 221.225 1.00 56.85  ? 472  GLN A CA  1 
ATOM   3564  C  C   . GLN A 1 472 ? 180.546 164.469 221.300 1.00 56.85  ? 472  GLN A C   1 
ATOM   3565  O  O   . GLN A 1 472 ? 181.171 164.738 222.332 1.00 56.85  ? 472  GLN A O   1 
ATOM   3566  C  CB  . GLN A 1 472 ? 180.417 162.093 220.507 1.00 56.85  ? 472  GLN A CB  1 
ATOM   3567  C  CG  . GLN A 1 472 ? 181.561 161.500 221.309 1.00 56.85  ? 472  GLN A CG  1 
ATOM   3568  C  CD  . GLN A 1 472 ? 181.117 161.000 222.670 1.00 56.85  ? 472  GLN A CD  1 
ATOM   3569  O  OE1 . GLN A 1 472 ? 181.495 161.554 223.701 1.00 56.85  ? 472  GLN A OE1 1 
ATOM   3570  N  NE2 . GLN A 1 472 ? 180.309 159.946 222.678 1.00 56.85  ? 472  GLN A NE2 1 
ATOM   3571  N  N   . GLU A 1 473 ? 180.595 165.246 220.216 1.00 58.34  ? 473  GLU A N   1 
ATOM   3572  C  CA  . GLU A 1 473 ? 181.415 166.453 220.206 1.00 58.34  ? 473  GLU A CA  1 
ATOM   3573  C  C   . GLU A 1 473 ? 180.897 167.486 221.199 1.00 58.34  ? 473  GLU A C   1 
ATOM   3574  O  O   . GLU A 1 473 ? 181.686 168.153 221.879 1.00 58.34  ? 473  GLU A O   1 
ATOM   3575  C  CB  . GLU A 1 473 ? 181.469 167.029 218.792 1.00 58.34  ? 473  GLU A CB  1 
ATOM   3576  C  CG  . GLU A 1 473 ? 182.363 166.241 217.841 1.00 58.34  ? 473  GLU A CG  1 
ATOM   3577  C  CD  . GLU A 1 473 ? 181.721 164.961 217.337 1.00 58.34  ? 473  GLU A CD  1 
ATOM   3578  O  OE1 . GLU A 1 473 ? 180.610 164.623 217.796 1.00 58.34  ? 473  GLU A OE1 1 
ATOM   3579  O  OE2 . GLU A 1 473 ? 182.331 164.287 216.481 1.00 58.34  ? 473  GLU A OE2 1 
ATOM   3580  N  N   . ILE A 1 474 ? 179.575 167.638 221.293 1.00 52.12  ? 474  ILE A N   1 
ATOM   3581  C  CA  . ILE A 1 474 ? 179.004 168.553 222.277 1.00 52.12  ? 474  ILE A CA  1 
ATOM   3582  C  C   . ILE A 1 474 ? 179.301 168.071 223.692 1.00 52.12  ? 474  ILE A C   1 
ATOM   3583  O  O   . ILE A 1 474 ? 179.673 168.863 224.567 1.00 52.12  ? 474  ILE A O   1 
ATOM   3584  C  CB  . ILE A 1 474 ? 177.493 168.718 222.042 1.00 52.12  ? 474  ILE A CB  1 
ATOM   3585  C  CG1 . ILE A 1 474 ? 177.227 169.310 220.657 1.00 52.12  ? 474  ILE A CG1 1 
ATOM   3586  C  CG2 . ILE A 1 474 ? 176.879 169.593 223.119 1.00 52.12  ? 474  ILE A CG2 1 
ATOM   3587  C  CD1 . ILE A 1 474 ? 177.582 170.771 220.542 1.00 52.12  ? 474  ILE A CD1 1 
ATOM   3588  N  N   . LEU A 1 475 ? 179.150 166.768 223.940 1.00 54.20  ? 475  LEU A N   1 
ATOM   3589  C  CA  . LEU A 1 475 ? 179.394 166.231 225.274 1.00 54.20  ? 475  LEU A CA  1 
ATOM   3590  C  C   . LEU A 1 475 ? 180.860 166.342 225.669 1.00 54.20  ? 475  LEU A C   1 
ATOM   3591  O  O   . LEU A 1 475 ? 181.174 166.430 226.861 1.00 54.20  ? 475  LEU A O   1 
ATOM   3592  C  CB  . LEU A 1 475 ? 178.936 164.775 225.345 1.00 54.20  ? 475  LEU A CB  1 
ATOM   3593  C  CG  . LEU A 1 475 ? 177.428 164.548 225.446 1.00 54.20  ? 475  LEU A CG  1 
ATOM   3594  C  CD1 . LEU A 1 475 ? 177.114 163.065 225.545 1.00 54.20  ? 475  LEU A CD1 1 
ATOM   3595  C  CD2 . LEU A 1 475 ? 176.852 165.302 226.633 1.00 54.20  ? 475  LEU A CD2 1 
ATOM   3596  N  N   . ASN A 1 476 ? 181.768 166.331 224.690 1.00 57.45  ? 476  ASN A N   1 
ATOM   3597  C  CA  . ASN A 1 476 ? 183.187 166.479 224.999 1.00 57.45  ? 476  ASN A CA  1 
ATOM   3598  C  C   . ASN A 1 476 ? 183.481 167.839 225.621 1.00 57.45  ? 476  ASN A C   1 
ATOM   3599  O  O   . ASN A 1 476 ? 184.399 167.969 226.439 1.00 57.45  ? 476  ASN A O   1 
ATOM   3600  C  CB  . ASN A 1 476 ? 184.024 166.276 223.737 1.00 57.45  ? 476  ASN A CB  1 
ATOM   3601  C  CG  . ASN A 1 476 ? 184.059 164.831 223.287 1.00 57.45  ? 476  ASN A CG  1 
ATOM   3602  O  OD1 . ASN A 1 476 ? 183.580 163.940 223.988 1.00 57.45  ? 476  ASN A OD1 1 
ATOM   3603  N  ND2 . ASN A 1 476 ? 184.625 164.592 222.111 1.00 57.45  ? 476  ASN A ND2 1 
ATOM   3604  N  N   . VAL A 1 477 ? 182.717 168.864 225.243 1.00 58.24  ? 477  VAL A N   1 
ATOM   3605  C  CA  . VAL A 1 477 ? 182.944 170.219 225.730 1.00 58.24  ? 477  VAL A CA  1 
ATOM   3606  C  C   . VAL A 1 477 ? 181.839 170.683 226.674 1.00 58.24  ? 477  VAL A C   1 
ATOM   3607  O  O   . VAL A 1 477 ? 181.656 171.890 226.858 1.00 58.24  ? 477  VAL A O   1 
ATOM   3608  C  CB  . VAL A 1 477 ? 183.110 171.203 224.562 1.00 58.24  ? 477  VAL A CB  1 
ATOM   3609  C  CG1 . VAL A 1 477 ? 184.428 170.956 223.847 1.00 58.24  ? 477  VAL A CG1 1 
ATOM   3610  C  CG2 . VAL A 1 477 ? 181.945 171.074 223.597 1.00 58.24  ? 477  VAL A CG2 1 
ATOM   3611  N  N   . CYS A 1 478 ? 181.097 169.758 227.275 1.00 60.60  ? 478  CYS A N   1 
ATOM   3612  C  CA  . CYS A 1 478 ? 180.042 170.096 228.222 1.00 60.60  ? 478  CYS A CA  1 
ATOM   3613  C  C   . CYS A 1 478 ? 180.413 169.600 229.613 1.00 60.60  ? 478  CYS A C   1 
ATOM   3614  O  O   . CYS A 1 478 ? 180.799 168.439 229.782 1.00 60.60  ? 478  CYS A O   1 
ATOM   3615  C  CB  . CYS A 1 478 ? 178.703 169.497 227.790 1.00 60.60  ? 478  CYS A CB  1 
ATOM   3616  S  SG  . CYS A 1 478 ? 177.816 170.475 226.561 1.00 60.60  ? 478  CYS A SG  1 
ATOM   3617  N  N   . SER A 1 479 ? 180.292 170.485 230.605 1.00 65.45  ? 479  SER A N   1 
ATOM   3618  C  CA  . SER A 1 479 ? 180.548 170.138 231.995 1.00 65.45  ? 479  SER A CA  1 
ATOM   3619  C  C   . SER A 1 479 ? 179.316 170.231 232.882 1.00 65.45  ? 479  SER A C   1 
ATOM   3620  O  O   . SER A 1 479 ? 179.292 169.600 233.943 1.00 65.45  ? 479  SER A O   1 
ATOM   3621  C  CB  . SER A 1 479 ? 181.647 171.041 232.577 1.00 65.45  ? 479  SER A CB  1 
ATOM   3622  O  OG  . SER A 1 479 ? 182.181 170.491 233.768 1.00 65.45  ? 479  SER A OG  1 
ATOM   3623  N  N   . GLN A 1 480 ? 178.304 170.994 232.479 1.00 66.02  ? 480  GLN A N   1 
ATOM   3624  C  CA  . GLN A 1 480 ? 177.079 171.156 233.246 1.00 66.02  ? 480  GLN A CA  1 
ATOM   3625  C  C   . GLN A 1 480 ? 175.885 170.839 232.358 1.00 66.02  ? 480  GLN A C   1 
ATOM   3626  O  O   . GLN A 1 480 ? 175.952 170.947 231.131 1.00 66.02  ? 480  GLN A O   1 
ATOM   3627  C  CB  . GLN A 1 480 ? 176.950 172.578 233.806 1.00 66.02  ? 480  GLN A CB  1 
ATOM   3628  C  CG  . GLN A 1 480 ? 178.097 173.007 234.701 1.00 66.02  ? 480  GLN A CG  1 
ATOM   3629  C  CD  . GLN A 1 480 ? 177.917 174.413 235.237 1.00 66.02  ? 480  GLN A CD  1 
ATOM   3630  O  OE1 . GLN A 1 480 ? 177.820 175.373 234.472 1.00 66.02  ? 480  GLN A OE1 1 
ATOM   3631  N  NE2 . GLN A 1 480 ? 177.865 174.541 236.557 1.00 66.02  ? 480  GLN A NE2 1 
ATOM   3632  N  N   . VAL A 1 481 ? 174.786 170.436 232.990 1.00 60.96  ? 481  VAL A N   1 
ATOM   3633  C  CA  . VAL A 1 481 ? 173.552 170.122 232.281 1.00 60.96  ? 481  VAL A CA  1 
ATOM   3634  C  C   . VAL A 1 481 ? 172.380 170.710 233.055 1.00 60.96  ? 481  VAL A C   1 
ATOM   3635  O  O   . VAL A 1 481 ? 172.366 170.701 234.290 1.00 60.96  ? 481  VAL A O   1 
ATOM   3636  C  CB  . VAL A 1 481 ? 173.388 168.600 232.070 1.00 60.96  ? 481  VAL A CB  1 
ATOM   3637  C  CG1 . VAL A 1 481 ? 173.295 167.872 233.399 1.00 60.96  ? 481  VAL A CG1 1 
ATOM   3638  C  CG2 . VAL A 1 481 ? 172.171 168.307 231.211 1.00 60.96  ? 481  VAL A CG2 1 
ATOM   3639  N  N   . ARG A 1 482 ? 171.408 171.247 232.322 1.00 59.23  ? 482  ARG A N   1 
ATOM   3640  C  CA  . ARG A 1 482 ? 170.216 171.843 232.921 1.00 59.23  ? 482  ARG A CA  1 
ATOM   3641  C  C   . ARG A 1 482 ? 169.173 170.745 233.085 1.00 59.23  ? 482  ARG A C   1 
ATOM   3642  O  O   . ARG A 1 482 ? 168.402 170.460 232.166 1.00 59.23  ? 482  ARG A O   1 
ATOM   3643  C  CB  . ARG A 1 482 ? 169.699 172.990 232.060 1.00 59.23  ? 482  ARG A CB  1 
ATOM   3644  C  CG  . ARG A 1 482 ? 168.705 173.894 232.764 1.00 59.23  ? 482  ARG A CG  1 
ATOM   3645  C  CD  . ARG A 1 482 ? 168.118 174.910 231.802 1.00 59.23  ? 482  ARG A CD  1 
ATOM   3646  N  NE  . ARG A 1 482 ? 169.115 175.875 231.354 1.00 59.23  ? 482  ARG A NE  1 
ATOM   3647  C  CZ  . ARG A 1 482 ? 169.446 176.973 232.020 1.00 59.23  ? 482  ARG A CZ  1 
ATOM   3648  N  NH1 . ARG A 1 482 ? 168.879 177.278 233.175 1.00 59.23  ? 482  ARG A NH1 1 
ATOM   3649  N  NH2 . ARG A 1 482 ? 170.367 177.787 231.512 1.00 59.23  ? 482  ARG A NH2 1 
ATOM   3650  N  N   . HIS A 1 483 ? 169.150 170.127 234.263 1.00 66.06  ? 483  HIS A N   1 
ATOM   3651  C  CA  . HIS A 1 483 ? 168.244 169.027 234.566 1.00 66.06  ? 483  HIS A CA  1 
ATOM   3652  C  C   . HIS A 1 483 ? 167.213 169.508 235.575 1.00 66.06  ? 483  HIS A C   1 
ATOM   3653  O  O   . HIS A 1 483 ? 167.575 170.066 236.617 1.00 66.06  ? 483  HIS A O   1 
ATOM   3654  C  CB  . HIS A 1 483 ? 169.012 167.820 235.109 1.00 66.06  ? 483  HIS A CB  1 
ATOM   3655  C  CG  . HIS A 1 483 ? 168.197 166.567 235.182 1.00 66.06  ? 483  HIS A CG  1 
ATOM   3656  N  ND1 . HIS A 1 483 ? 168.601 165.459 235.894 1.00 66.06  ? 483  HIS A ND1 1 
ATOM   3657  C  CD2 . HIS A 1 483 ? 167.002 166.247 234.632 1.00 66.06  ? 483  HIS A CD2 1 
ATOM   3658  C  CE1 . HIS A 1 483 ? 167.690 164.509 235.780 1.00 66.06  ? 483  HIS A CE1 1 
ATOM   3659  N  NE2 . HIS A 1 483 ? 166.709 164.962 235.020 1.00 66.06  ? 483  HIS A NE2 1 
ATOM   3660  N  N   . ASN A 1 484 ? 165.933 169.305 235.254 1.00 70.24  ? 484  ASN A N   1 
ATOM   3661  C  CA  . ASN A 1 484 ? 164.820 169.678 236.128 1.00 70.24  ? 484  ASN A CA  1 
ATOM   3662  C  C   . ASN A 1 484 ? 164.853 171.160 236.491 1.00 70.24  ? 484  ASN A C   1 
ATOM   3663  O  O   . ASN A 1 484 ? 164.429 171.553 237.580 1.00 70.24  ? 484  ASN A O   1 
ATOM   3664  C  CB  . ASN A 1 484 ? 164.796 168.818 237.394 1.00 70.24  ? 484  ASN A CB  1 
ATOM   3665  C  CG  . ASN A 1 484 ? 164.837 167.334 237.090 1.00 70.24  ? 484  ASN A CG  1 
ATOM   3666  O  OD1 . ASN A 1 484 ? 164.180 166.861 236.163 1.00 70.24  ? 484  ASN A OD1 1 
ATOM   3667  N  ND2 . ASN A 1 484 ? 165.613 166.591 237.870 1.00 70.24  ? 484  ASN A ND2 1 
ATOM   3668  N  N   . GLY A 1 485 ? 165.359 171.993 235.584 1.00 72.06  ? 485  GLY A N   1 
ATOM   3669  C  CA  . GLY A 1 485 ? 165.449 173.417 235.818 1.00 72.06  ? 485  GLY A CA  1 
ATOM   3670  C  C   . GLY A 1 485 ? 166.641 173.864 236.635 1.00 72.06  ? 485  GLY A C   1 
ATOM   3671  O  O   . GLY A 1 485 ? 166.752 175.061 236.929 1.00 72.06  ? 485  GLY A O   1 
ATOM   3672  N  N   . GLU A 1 486 ? 167.532 172.952 237.014 1.00 73.41  ? 486  GLU A N   1 
ATOM   3673  C  CA  . GLU A 1 486 ? 168.702 173.281 237.814 1.00 73.41  ? 486  GLU A CA  1 
ATOM   3674  C  C   . GLU A 1 486 ? 169.973 172.892 237.072 1.00 73.41  ? 486  GLU A C   1 
ATOM   3675  O  O   . GLU A 1 486 ? 170.025 171.849 236.413 1.00 73.41  ? 486  GLU A O   1 
ATOM   3676  C  CB  . GLU A 1 486 ? 168.656 172.578 239.172 1.00 73.41  ? 486  GLU A CB  1 
ATOM   3677  C  CG  . GLU A 1 486 ? 167.455 172.950 240.023 1.00 73.41  ? 486  GLU A CG  1 
ATOM   3678  C  CD  . GLU A 1 486 ? 167.401 172.174 241.324 1.00 73.41  ? 486  GLU A CD  1 
ATOM   3679  O  OE1 . GLU A 1 486 ? 167.980 171.069 241.382 1.00 73.41  ? 486  GLU A OE1 1 
ATOM   3680  O  OE2 . GLU A 1 486 ? 166.782 172.670 242.289 1.00 73.41  ? 486  GLU A OE2 1 
ATOM   3681  N  N   . ILE A 1 487 ? 170.995 173.736 237.183 1.00 66.11  ? 487  ILE A N   1 
ATOM   3682  C  CA  . ILE A 1 487 ? 172.285 173.478 236.553 1.00 66.11  ? 487  ILE A CA  1 
ATOM   3683  C  C   . ILE A 1 487 ? 173.068 172.525 237.450 1.00 66.11  ? 487  ILE A C   1 
ATOM   3684  O  O   . ILE A 1 487 ? 173.532 172.912 238.525 1.00 66.11  ? 487  ILE A O   1 
ATOM   3685  C  CB  . ILE A 1 487 ? 173.061 174.777 236.312 1.00 66.11  ? 487  ILE A CB  1 
ATOM   3686  C  CG1 . ILE A 1 487 ? 172.194 175.785 235.556 1.00 66.11  ? 487  ILE A CG1 1 
ATOM   3687  C  CG2 . ILE A 1 487 ? 174.343 174.497 235.548 1.00 66.11  ? 487  ILE A CG2 1 
ATOM   3688  C  CD1 . ILE A 1 487 ? 171.817 175.338 234.163 1.00 66.11  ? 487  ILE A CD1 1 
ATOM   3689  N  N   . VAL A 1 488 ? 173.219 171.279 237.012 1.00 67.59  ? 488  VAL A N   1 
ATOM   3690  C  CA  . VAL A 1 488 ? 173.912 170.263 237.799 1.00 67.59  ? 488  VAL A CA  1 
ATOM   3691  C  C   . VAL A 1 488 ? 175.139 169.793 237.023 1.00 67.59  ? 488  VAL A C   1 
ATOM   3692  O  O   . VAL A 1 488 ? 175.095 169.711 235.787 1.00 67.59  ? 488  VAL A O   1 
ATOM   3693  C  CB  . VAL A 1 488 ? 172.964 169.101 238.150 1.00 67.59  ? 488  VAL A CB  1 
ATOM   3694  C  CG1 . VAL A 1 488 ? 172.545 168.341 236.902 1.00 67.59  ? 488  VAL A CG1 1 
ATOM   3695  C  CG2 . VAL A 1 488 ? 173.596 168.160 239.166 1.00 67.59  ? 488  VAL A CG2 1 
ATOM   3696  N  N   . PRO A 1 489 ? 176.259 169.514 237.692 1.00 67.82  ? 489  PRO A N   1 
ATOM   3697  C  CA  . PRO A 1 489 ? 177.426 168.981 236.979 1.00 67.82  ? 489  PRO A CA  1 
ATOM   3698  C  C   . PRO A 1 489 ? 177.101 167.673 236.273 1.00 67.82  ? 489  PRO A C   1 
ATOM   3699  O  O   . PRO A 1 489 ? 176.357 166.834 236.784 1.00 67.82  ? 489  PRO A O   1 
ATOM   3700  C  CB  . PRO A 1 489 ? 178.456 168.780 238.094 1.00 67.82  ? 489  PRO A CB  1 
ATOM   3701  C  CG  . PRO A 1 489 ? 178.099 169.811 239.104 1.00 67.82  ? 489  PRO A CG  1 
ATOM   3702  C  CD  . PRO A 1 489 ? 176.597 169.926 239.067 1.00 67.82  ? 489  PRO A CD  1 
ATOM   3703  N  N   . LEU A 1 490 ? 177.674 167.508 235.081 1.00 68.38  ? 490  LEU A N   1 
ATOM   3704  C  CA  . LEU A 1 490 ? 177.405 166.350 234.230 1.00 68.38  ? 490  LEU A CA  1 
ATOM   3705  C  C   . LEU A 1 490 ? 178.390 165.246 234.594 1.00 68.38  ? 490  LEU A C   1 
ATOM   3706  O  O   . LEU A 1 490 ? 179.548 165.251 234.175 1.00 68.38  ? 490  LEU A O   1 
ATOM   3707  C  CB  . LEU A 1 490 ? 177.505 166.737 232.760 1.00 68.38  ? 490  LEU A CB  1 
ATOM   3708  C  CG  . LEU A 1 490 ? 177.134 165.678 231.723 1.00 68.38  ? 490  LEU A CG  1 
ATOM   3709  C  CD1 . LEU A 1 490 ? 175.671 165.292 231.853 1.00 68.38  ? 490  LEU A CD1 1 
ATOM   3710  C  CD2 . LEU A 1 490 ? 177.430 166.191 230.324 1.00 68.38  ? 490  LEU A CD2 1 
ATOM   3711  N  N   . ASP A 1 491 ? 177.921 164.285 235.385 1.00 74.53  ? 491  ASP A N   1 
ATOM   3712  C  CA  . ASP A 1 491 ? 178.759 163.183 235.830 1.00 74.53  ? 491  ASP A CA  1 
ATOM   3713  C  C   . ASP A 1 491 ? 178.743 162.048 234.805 1.00 74.53  ? 491  ASP A C   1 
ATOM   3714  O  O   . ASP A 1 491 ? 178.143 162.146 233.731 1.00 74.53  ? 491  ASP A O   1 
ATOM   3715  C  CB  . ASP A 1 491 ? 178.307 162.693 237.203 1.00 74.53  ? 491  ASP A CB  1 
ATOM   3716  C  CG  . ASP A 1 491 ? 176.812 162.472 237.279 1.00 74.53  ? 491  ASP A CG  1 
ATOM   3717  O  OD1 . ASP A 1 491 ? 176.113 162.800 236.298 1.00 74.53  ? 491  ASP A OD1 1 
ATOM   3718  O  OD2 . ASP A 1 491 ? 176.335 161.970 238.318 1.00 74.53  ? 491  ASP A OD2 1 
ATOM   3719  N  N   . ASP A 1 492 ? 179.419 160.949 235.149 1.00 71.69  ? 492  ASP A N   1 
ATOM   3720  C  CA  . ASP A 1 492 ? 179.544 159.827 234.224 1.00 71.69  ? 492  ASP A CA  1 
ATOM   3721  C  C   . ASP A 1 492 ? 178.231 159.074 234.051 1.00 71.69  ? 492  ASP A C   1 
ATOM   3722  O  O   . ASP A 1 492 ? 177.958 158.556 232.962 1.00 71.69  ? 492  ASP A O   1 
ATOM   3723  C  CB  . ASP A 1 492 ? 180.638 158.875 234.705 1.00 71.69  ? 492  ASP A CB  1 
ATOM   3724  C  CG  . ASP A 1 492 ? 181.396 158.233 233.560 1.00 71.69  ? 492  ASP A CG  1 
ATOM   3725  O  OD1 . ASP A 1 492 ? 180.787 158.006 232.495 1.00 71.69  ? 492  ASP A OD1 1 
ATOM   3726  O  OD2 . ASP A 1 492 ? 182.603 157.956 233.727 1.00 71.69  ? 492  ASP A OD2 1 
ATOM   3727  N  N   . ILE A 1 493 ? 177.418 158.987 235.107 1.00 70.91  ? 493  ILE A N   1 
ATOM   3728  C  CA  . ILE A 1 493 ? 176.160 158.247 235.020 1.00 70.91  ? 493  ILE A CA  1 
ATOM   3729  C  C   . ILE A 1 493 ? 175.229 158.899 234.005 1.00 70.91  ? 493  ILE A C   1 
ATOM   3730  O  O   . ILE A 1 493 ? 174.633 158.223 233.155 1.00 70.91  ? 493  ILE A O   1 
ATOM   3731  C  CB  . ILE A 1 493 ? 175.500 158.146 236.407 1.00 70.91  ? 493  ILE A CB  1 
ATOM   3732  C  CG1 . ILE A 1 493 ? 176.528 157.720 237.457 1.00 70.91  ? 493  ILE A CG1 1 
ATOM   3733  C  CG2 . ILE A 1 493 ? 174.331 157.174 236.370 1.00 70.91  ? 493  ILE A CG2 1 
ATOM   3734  C  CD1 . ILE A 1 493 ? 177.090 156.333 237.237 1.00 70.91  ? 493  ILE A CD1 1 
ATOM   3735  N  N   . MET A 1 494 ? 175.088 160.225 234.082 1.00 70.38  ? 494  MET A N   1 
ATOM   3736  C  CA  . MET A 1 494 ? 174.266 160.935 233.109 1.00 70.38  ? 494  MET A CA  1 
ATOM   3737  C  C   . MET A 1 494 ? 174.839 160.817 231.705 1.00 70.38  ? 494  MET A C   1 
ATOM   3738  O  O   . MET A 1 494 ? 174.082 160.707 230.736 1.00 70.38  ? 494  MET A O   1 
ATOM   3739  C  CB  . MET A 1 494 ? 174.123 162.404 233.506 1.00 70.38  ? 494  MET A CB  1 
ATOM   3740  C  CG  . MET A 1 494 ? 173.309 162.628 234.770 1.00 70.38  ? 494  MET A CG  1 
ATOM   3741  S  SD  . MET A 1 494 ? 172.703 164.321 234.908 1.00 70.38  ? 494  MET A SD  1 
ATOM   3742  C  CE  . MET A 1 494 ? 172.204 164.365 236.627 1.00 70.38  ? 494  MET A CE  1 
ATOM   3743  N  N   . LEU A 1 495 ? 176.168 160.836 231.574 1.00 65.33  ? 495  LEU A N   1 
ATOM   3744  C  CA  . LEU A 1 495 ? 176.783 160.662 230.263 1.00 65.33  ? 495  LEU A CA  1 
ATOM   3745  C  C   . LEU A 1 495 ? 176.434 159.306 229.662 1.00 65.33  ? 495  LEU A C   1 
ATOM   3746  O  O   . LEU A 1 495 ? 176.070 159.219 228.484 1.00 65.33  ? 495  LEU A O   1 
ATOM   3747  C  CB  . LEU A 1 495 ? 178.299 160.825 230.368 1.00 65.33  ? 495  LEU A CB  1 
ATOM   3748  C  CG  . LEU A 1 495 ? 178.836 162.256 230.377 1.00 65.33  ? 495  LEU A CG  1 
ATOM   3749  C  CD1 . LEU A 1 495 ? 180.340 162.261 230.593 1.00 65.33  ? 495  LEU A CD1 1 
ATOM   3750  C  CD2 . LEU A 1 495 ? 178.483 162.952 229.077 1.00 65.33  ? 495  LEU A CD2 1 
ATOM   3751  N  N   . ARG A 1 496 ? 176.521 158.239 230.460 1.00 64.30  ? 496  ARG A N   1 
ATOM   3752  C  CA  . ARG A 1 496 ? 176.205 156.910 229.948 1.00 64.30  ? 496  ARG A CA  1 
ATOM   3753  C  C   . ARG A 1 496 ? 174.720 156.774 229.631 1.00 64.30  ? 496  ARG A C   1 
ATOM   3754  O  O   . ARG A 1 496 ? 174.348 156.139 228.636 1.00 64.30  ? 496  ARG A O   1 
ATOM   3755  C  CB  . ARG A 1 496 ? 176.646 155.843 230.948 1.00 64.30  ? 496  ARG A CB  1 
ATOM   3756  C  CG  . ARG A 1 496 ? 178.151 155.787 231.161 1.00 64.30  ? 496  ARG A CG  1 
ATOM   3757  C  CD  . ARG A 1 496 ? 178.551 154.613 232.040 1.00 64.30  ? 496  ARG A CD  1 
ATOM   3758  N  NE  . ARG A 1 496 ? 177.878 154.639 233.334 1.00 64.30  ? 496  ARG A NE  1 
ATOM   3759  C  CZ  . ARG A 1 496 ? 177.086 153.677 233.786 1.00 64.30  ? 496  ARG A CZ  1 
ATOM   3760  N  NH1 . ARG A 1 496 ? 176.841 152.590 233.071 1.00 64.30  ? 496  ARG A NH1 1 
ATOM   3761  N  NH2 . ARG A 1 496 ? 176.526 153.806 234.985 1.00 64.30  ? 496  ARG A NH2 1 
ATOM   3762  N  N   . LYS A 1 497 ? 173.856 157.360 230.464 1.00 59.76  ? 497  LYS A N   1 
ATOM   3763  C  CA  . LYS A 1 497 ? 172.423 157.319 230.185 1.00 59.76  ? 497  LYS A CA  1 
ATOM   3764  C  C   . LYS A 1 497 ? 172.098 158.048 228.886 1.00 59.76  ? 497  LYS A C   1 
ATOM   3765  O  O   . LYS A 1 497 ? 171.323 157.554 228.056 1.00 59.76  ? 497  LYS A O   1 
ATOM   3766  C  CB  . LYS A 1 497 ? 171.650 157.923 231.358 1.00 59.76  ? 497  LYS A CB  1 
ATOM   3767  C  CG  . LYS A 1 497 ? 170.211 158.289 231.043 1.00 59.76  ? 497  LYS A CG  1 
ATOM   3768  C  CD  . LYS A 1 497 ? 169.571 159.032 232.203 1.00 59.76  ? 497  LYS A CD  1 
ATOM   3769  C  CE  . LYS A 1 497 ? 168.150 159.457 231.873 1.00 59.76  ? 497  LYS A CE  1 
ATOM   3770  N  NZ  . LYS A 1 497 ? 167.508 160.177 233.007 1.00 59.76  ? 497  LYS A NZ  1 
ATOM   3771  N  N   . ILE A 1 498 ? 172.698 159.223 228.686 1.00 56.74  ? 498  ILE A N   1 
ATOM   3772  C  CA  . ILE A 1 498 ? 172.496 159.970 227.449 1.00 56.74  ? 498  ILE A CA  1 
ATOM   3773  C  C   . ILE A 1 498 ? 172.998 159.160 226.262 1.00 56.74  ? 498  ILE A C   1 
ATOM   3774  O  O   . ILE A 1 498 ? 172.349 159.094 225.211 1.00 56.74  ? 498  ILE A O   1 
ATOM   3775  C  CB  . ILE A 1 498 ? 173.192 161.340 227.533 1.00 56.74  ? 498  ILE A CB  1 
ATOM   3776  C  CG1 . ILE A 1 498 ? 172.395 162.291 228.425 1.00 56.74  ? 498  ILE A CG1 1 
ATOM   3777  C  CG2 . ILE A 1 498 ? 173.375 161.938 226.149 1.00 56.74  ? 498  ILE A CG2 1 
ATOM   3778  C  CD1 . ILE A 1 498 ? 173.126 163.574 228.742 1.00 56.74  ? 498  ILE A CD1 1 
ATOM   3779  N  N   . LYS A 1 499 ? 174.163 158.528 226.417 1.00 59.60  ? 499  LYS A N   1 
ATOM   3780  C  CA  . LYS A 1 499 ? 174.722 157.728 225.335 1.00 59.60  ? 499  LYS A CA  1 
ATOM   3781  C  C   . LYS A 1 499 ? 173.793 156.583 224.956 1.00 59.60  ? 499  LYS A C   1 
ATOM   3782  O  O   . LYS A 1 499 ? 173.559 156.339 223.769 1.00 59.60  ? 499  LYS A O   1 
ATOM   3783  C  CB  . LYS A 1 499 ? 176.097 157.194 225.731 1.00 59.60  ? 499  LYS A CB  1 
ATOM   3784  C  CG  . LYS A 1 499 ? 176.730 156.288 224.690 1.00 59.60  ? 499  LYS A CG  1 
ATOM   3785  C  CD  . LYS A 1 499 ? 178.003 155.649 225.217 1.00 59.60  ? 499  LYS A CD  1 
ATOM   3786  C  CE  . LYS A 1 499 ? 178.576 154.654 224.221 1.00 59.60  ? 499  LYS A CE  1 
ATOM   3787  N  NZ  . LYS A 1 499 ? 177.606 153.573 223.897 1.00 59.60  ? 499  LYS A NZ  1 
ATOM   3788  N  N   . ARG A 1 500 ? 173.241 155.877 225.946 1.00 57.30  ? 500  ARG A N   1 
ATOM   3789  C  CA  . ARG A 1 500 ? 172.381 154.739 225.630 1.00 57.30  ? 500  ARG A CA  1 
ATOM   3790  C  C   . ARG A 1 500 ? 171.064 155.197 225.008 1.00 57.30  ? 500  ARG A C   1 
ATOM   3791  O  O   . ARG A 1 500 ? 170.558 154.570 224.067 1.00 57.30  ? 500  ARG A O   1 
ATOM   3792  C  CB  . ARG A 1 500 ? 172.139 153.881 226.877 1.00 57.30  ? 500  ARG A CB  1 
ATOM   3793  C  CG  . ARG A 1 500 ? 171.210 154.474 227.920 1.00 57.30  ? 500  ARG A CG  1 
ATOM   3794  C  CD  . ARG A 1 500 ? 171.083 153.564 229.129 1.00 57.30  ? 500  ARG A CD  1 
ATOM   3795  N  NE  . ARG A 1 500 ? 170.163 154.107 230.122 1.00 57.30  ? 500  ARG A NE  1 
ATOM   3796  C  CZ  . ARG A 1 500 ? 169.895 153.533 231.287 1.00 57.30  ? 500  ARG A CZ  1 
ATOM   3797  N  NH1 . ARG A 1 500 ? 170.461 152.392 231.642 1.00 57.30  ? 500  ARG A NH1 1 
ATOM   3798  N  NH2 . ARG A 1 500 ? 169.036 154.120 232.116 1.00 57.30  ? 500  ARG A NH2 1 
ATOM   3799  N  N   . VAL A 1 501 ? 170.498 156.303 225.504 1.00 49.40  ? 501  VAL A N   1 
ATOM   3800  C  CA  . VAL A 1 501 ? 169.250 156.806 224.931 1.00 49.40  ? 501  VAL A CA  1 
ATOM   3801  C  C   . VAL A 1 501 ? 169.464 157.231 223.483 1.00 49.40  ? 501  VAL A C   1 
ATOM   3802  O  O   . VAL A 1 501 ? 168.662 156.913 222.595 1.00 49.40  ? 501  VAL A O   1 
ATOM   3803  C  CB  . VAL A 1 501 ? 168.688 157.959 225.781 1.00 49.40  ? 501  VAL A CB  1 
ATOM   3804  C  CG1 . VAL A 1 501 ? 167.484 158.579 225.096 1.00 49.40  ? 501  VAL A CG1 1 
ATOM   3805  C  CG2 . VAL A 1 501 ? 168.300 157.452 227.157 1.00 49.40  ? 501  VAL A CG2 1 
ATOM   3806  N  N   . THR A 1 502 ? 170.557 157.950 223.221 1.00 49.11  ? 502  THR A N   1 
ATOM   3807  C  CA  . THR A 1 502 ? 170.828 158.395 221.859 1.00 49.11  ? 502  THR A CA  1 
ATOM   3808  C  C   . THR A 1 502 ? 171.186 157.225 220.954 1.00 49.11  ? 502  THR A C   1 
ATOM   3809  O  O   . THR A 1 502 ? 170.897 157.254 219.754 1.00 49.11  ? 502  THR A O   1 
ATOM   3810  C  CB  . THR A 1 502 ? 171.942 159.437 221.860 1.00 49.11  ? 502  THR A CB  1 
ATOM   3811  O  OG1 . THR A 1 502 ? 173.085 158.908 222.541 1.00 49.11  ? 502  THR A OG1 1 
ATOM   3812  C  CG2 . THR A 1 502 ? 171.473 160.705 222.555 1.00 49.11  ? 502  THR A CG2 1 
ATOM   3813  N  N   . ASP A 1 503 ? 171.814 156.183 221.504 1.00 52.18  ? 503  ASP A N   1 
ATOM   3814  C  CA  . ASP A 1 503 ? 172.073 154.986 220.712 1.00 52.18  ? 503  ASP A CA  1 
ATOM   3815  C  C   . ASP A 1 503 ? 170.773 154.301 220.316 1.00 52.18  ? 503  ASP A C   1 
ATOM   3816  O  O   . ASP A 1 503 ? 170.626 153.843 219.178 1.00 52.18  ? 503  ASP A O   1 
ATOM   3817  C  CB  . ASP A 1 503 ? 172.977 154.027 221.485 1.00 52.18  ? 503  ASP A CB  1 
ATOM   3818  C  CG  . ASP A 1 503 ? 174.433 154.445 221.450 1.00 52.18  ? 503  ASP A CG  1 
ATOM   3819  O  OD1 . ASP A 1 503 ? 174.731 155.521 220.890 1.00 52.18  ? 503  ASP A OD1 1 
ATOM   3820  O  OD2 . ASP A 1 503 ? 175.281 153.697 221.981 1.00 52.18  ? 503  ASP A OD2 1 
ATOM   3821  N  N   . THR A 1 504 ? 169.815 154.224 221.243 1.00 47.44  ? 504  THR A N   1 
ATOM   3822  C  CA  . THR A 1 504 ? 168.510 153.666 220.901 1.00 47.44  ? 504  THR A CA  1 
ATOM   3823  C  C   . THR A 1 504 ? 167.814 154.507 219.837 1.00 47.44  ? 504  THR A C   1 
ATOM   3824  O  O   . THR A 1 504 ? 167.234 153.968 218.883 1.00 47.44  ? 504  THR A O   1 
ATOM   3825  C  CB  . THR A 1 504 ? 167.640 153.556 222.151 1.00 47.44  ? 504  THR A CB  1 
ATOM   3826  O  OG1 . THR A 1 504 ? 168.346 152.828 223.163 1.00 47.44  ? 504  THR A OG1 1 
ATOM   3827  C  CG2 . THR A 1 504 ? 166.340 152.836 221.831 1.00 47.44  ? 504  THR A CG2 1 
ATOM   3828  N  N   . LEU A 1 505 ? 167.870 155.835 219.977 1.00 43.17  ? 505  LEU A N   1 
ATOM   3829  C  CA  . LEU A 1 505 ? 167.265 156.709 218.976 1.00 43.17  ? 505  LEU A CA  1 
ATOM   3830  C  C   . LEU A 1 505 ? 167.926 156.545 217.612 1.00 43.17  ? 505  LEU A C   1 
ATOM   3831  O  O   . LEU A 1 505 ? 167.234 156.535 216.588 1.00 43.17  ? 505  LEU A O   1 
ATOM   3832  C  CB  . LEU A 1 505 ? 167.339 158.167 219.430 1.00 43.17  ? 505  LEU A CB  1 
ATOM   3833  C  CG  . LEU A 1 505 ? 166.553 158.547 220.686 1.00 43.17  ? 505  LEU A CG  1 
ATOM   3834  C  CD1 . LEU A 1 505 ? 166.340 160.050 220.746 1.00 43.17  ? 505  LEU A CD1 1 
ATOM   3835  C  CD2 . LEU A 1 505 ? 165.222 157.816 220.738 1.00 43.17  ? 505  LEU A CD2 1 
ATOM   3836  N  N   . ASN A 1 506 ? 169.254 156.423 217.578 1.00 42.75  ? 506  ASN A N   1 
ATOM   3837  C  CA  . ASN A 1 506 ? 169.954 156.182 216.322 1.00 42.75  ? 506  ASN A CA  1 
ATOM   3838  C  C   . ASN A 1 506 ? 169.546 154.846 215.716 1.00 42.75  ? 506  ASN A C   1 
ATOM   3839  O  O   . ASN A 1 506 ? 169.336 154.745 214.501 1.00 42.75  ? 506  ASN A O   1 
ATOM   3840  C  CB  . ASN A 1 506 ? 171.465 156.227 216.551 1.00 42.75  ? 506  ASN A CB  1 
ATOM   3841  C  CG  . ASN A 1 506 ? 172.008 157.642 216.602 1.00 42.75  ? 506  ASN A CG  1 
ATOM   3842  O  OD1 . ASN A 1 506 ? 171.350 158.589 216.177 1.00 42.75  ? 506  ASN A OD1 1 
ATOM   3843  N  ND2 . ASN A 1 506 ? 173.218 157.790 217.127 1.00 42.75  ? 506  ASN A ND2 1 
ATOM   3844  N  N   . ARG A 1 507 ? 169.429 153.807 216.547 1.00 44.09  ? 507  ARG A N   1 
ATOM   3845  C  CA  . ARG A 1 507 ? 168.960 152.509 216.083 1.00 44.09  ? 507  ARG A CA  1 
ATOM   3846  C  C   . ARG A 1 507 ? 167.541 152.564 215.541 1.00 44.09  ? 507  ARG A C   1 
ATOM   3847  O  O   . ARG A 1 507 ? 167.196 151.751 214.678 1.00 44.09  ? 507  ARG A O   1 
ATOM   3848  C  CB  . ARG A 1 507 ? 169.040 151.484 217.215 1.00 44.09  ? 507  ARG A CB  1 
ATOM   3849  C  CG  . ARG A 1 507 ? 170.337 150.695 217.250 1.00 44.09  ? 507  ARG A CG  1 
ATOM   3850  C  CD  . ARG A 1 507 ? 170.474 149.920 218.549 1.00 44.09  ? 507  ARG A CD  1 
ATOM   3851  N  NE  . ARG A 1 507 ? 171.862 149.822 218.982 1.00 44.09  ? 507  ARG A NE  1 
ATOM   3852  C  CZ  . ARG A 1 507 ? 172.258 149.882 220.246 1.00 44.09  ? 507  ARG A CZ  1 
ATOM   3853  N  NH1 . ARG A 1 507 ? 171.393 150.040 221.235 1.00 44.09  ? 507  ARG A NH1 1 
ATOM   3854  N  NH2 . ARG A 1 507 ? 173.554 149.779 220.526 1.00 44.09  ? 507  ARG A NH2 1 
ATOM   3855  N  N   . GLN A 1 508 ? 166.719 153.493 216.021 1.00 41.88  ? 508  GLN A N   1 
ATOM   3856  C  CA  . GLN A 1 508 ? 165.400 153.715 215.444 1.00 41.88  ? 508  GLN A CA  1 
ATOM   3857  C  C   . GLN A 1 508 ? 165.447 154.574 214.186 1.00 41.88  ? 508  GLN A C   1 
ATOM   3858  O  O   . GLN A 1 508 ? 164.394 154.839 213.597 1.00 41.88  ? 508  GLN A O   1 
ATOM   3859  C  CB  . GLN A 1 508 ? 164.465 154.362 216.471 1.00 41.88  ? 508  GLN A CB  1 
ATOM   3860  C  CG  . GLN A 1 508 ? 164.040 153.434 217.593 1.00 41.88  ? 508  GLN A CG  1 
ATOM   3861  C  CD  . GLN A 1 508 ? 162.848 153.964 218.364 1.00 41.88  ? 508  GLN A CD  1 
ATOM   3862  O  OE1 . GLN A 1 508 ? 161.862 154.405 217.776 1.00 41.88  ? 508  GLN A OE1 1 
ATOM   3863  N  NE2 . GLN A 1 508 ? 162.930 153.916 219.688 1.00 41.88  ? 508  GLN A NE2 1 
ATOM   3864  N  N   . GLY A 1 509 ? 166.631 155.009 213.764 1.00 40.10  ? 509  GLY A N   1 
ATOM   3865  C  CA  . GLY A 1 509 ? 166.770 155.838 212.586 1.00 40.10  ? 509  GLY A CA  1 
ATOM   3866  C  C   . GLY A 1 509 ? 166.708 157.328 212.828 1.00 40.10  ? 509  GLY A C   1 
ATOM   3867  O  O   . GLY A 1 509 ? 166.734 158.097 211.859 1.00 40.10  ? 509  GLY A O   1 
ATOM   3868  N  N   . LEU A 1 510 ? 166.627 157.762 214.081 1.00 38.01  ? 510  LEU A N   1 
ATOM   3869  C  CA  . LEU A 1 510 ? 166.560 159.176 214.425 1.00 38.01  ? 510  LEU A CA  1 
ATOM   3870  C  C   . LEU A 1 510 ? 167.972 159.733 214.544 1.00 38.01  ? 510  LEU A C   1 
ATOM   3871  O  O   . LEU A 1 510 ? 168.803 159.175 215.266 1.00 38.01  ? 510  LEU A O   1 
ATOM   3872  C  CB  . LEU A 1 510 ? 165.800 159.380 215.734 1.00 38.01  ? 510  LEU A CB  1 
ATOM   3873  C  CG  . LEU A 1 510 ? 164.292 159.150 215.716 1.00 38.01  ? 510  LEU A CG  1 
ATOM   3874  C  CD1 . LEU A 1 510 ? 163.734 159.205 217.126 1.00 38.01  ? 510  LEU A CD1 1 
ATOM   3875  C  CD2 . LEU A 1 510 ? 163.629 160.193 214.843 1.00 38.01  ? 510  LEU A CD2 1 
ATOM   3876  N  N   . ARG A 1 511 ? 168.237 160.829 213.840 1.00 36.93  ? 511  ARG A N   1 
ATOM   3877  C  CA  . ARG A 1 511 ? 169.477 161.564 214.033 1.00 36.93  ? 511  ARG A CA  1 
ATOM   3878  C  C   . ARG A 1 511 ? 169.330 162.506 215.219 1.00 36.93  ? 511  ARG A C   1 
ATOM   3879  O  O   . ARG A 1 511 ? 168.311 163.185 215.367 1.00 36.93  ? 511  ARG A O   1 
ATOM   3880  C  CB  . ARG A 1 511 ? 169.840 162.350 212.775 1.00 36.93  ? 511  ARG A CB  1 
ATOM   3881  C  CG  . ARG A 1 511 ? 170.003 161.497 211.530 1.00 36.93  ? 511  ARG A CG  1 
ATOM   3882  C  CD  . ARG A 1 511 ? 170.177 162.363 210.293 1.00 36.93  ? 511  ARG A CD  1 
ATOM   3883  N  NE  . ARG A 1 511 ? 171.347 163.225 210.397 1.00 36.93  ? 511  ARG A NE  1 
ATOM   3884  C  CZ  . ARG A 1 511 ? 171.642 164.194 209.541 1.00 36.93  ? 511  ARG A CZ  1 
ATOM   3885  N  NH1 . ARG A 1 511 ? 170.874 164.450 208.495 1.00 36.93  ? 511  ARG A NH1 1 
ATOM   3886  N  NH2 . ARG A 1 511 ? 172.735 164.925 209.741 1.00 36.93  ? 511  ARG A NH2 1 
ATOM   3887  N  N   . VAL A 1 512 ? 170.355 162.548 216.065 1.00 35.66  ? 512  VAL A N   1 
ATOM   3888  C  CA  . VAL A 1 512 ? 170.326 163.313 217.306 1.00 35.66  ? 512  VAL A CA  1 
ATOM   3889  C  C   . VAL A 1 512 ? 171.382 164.405 217.231 1.00 35.66  ? 512  VAL A C   1 
ATOM   3890  O  O   . VAL A 1 512 ? 172.551 164.130 216.934 1.00 35.66  ? 512  VAL A O   1 
ATOM   3891  C  CB  . VAL A 1 512 ? 170.555 162.406 218.528 1.00 35.66  ? 512  VAL A CB  1 
ATOM   3892  C  CG1 . VAL A 1 512 ? 170.780 163.241 219.773 1.00 35.66  ? 512  VAL A CG1 1 
ATOM   3893  C  CG2 . VAL A 1 512 ? 169.373 161.471 218.719 1.00 35.66  ? 512  VAL A CG2 1 
ATOM   3894  N  N   . VAL A 1 513 ? 170.969 165.641 217.497 1.00 39.00  ? 513  VAL A N   1 
ATOM   3895  C  CA  . VAL A 1 513 ? 171.857 166.798 217.497 1.00 39.00  ? 513  VAL A CA  1 
ATOM   3896  C  C   . VAL A 1 513 ? 171.728 167.485 218.848 1.00 39.00  ? 513  VAL A C   1 
ATOM   3897  O  O   . VAL A 1 513 ? 170.623 167.867 219.254 1.00 39.00  ? 513  VAL A O   1 
ATOM   3898  C  CB  . VAL A 1 513 ? 171.528 167.768 216.352 1.00 39.00  ? 513  VAL A CB  1 
ATOM   3899  C  CG1 . VAL A 1 513 ? 172.107 169.144 216.635 1.00 39.00  ? 513  VAL A CG1 1 
ATOM   3900  C  CG2 . VAL A 1 513 ? 172.051 167.223 215.032 1.00 39.00  ? 513  VAL A CG2 1 
ATOM   3901  N  N   . ALA A 1 514 ? 172.851 167.644 219.540 1.00 44.80  ? 514  ALA A N   1 
ATOM   3902  C  CA  . ALA A 1 514 ? 172.866 168.241 220.865 1.00 44.80  ? 514  ALA A CA  1 
ATOM   3903  C  C   . ALA A 1 514 ? 173.126 169.739 220.782 1.00 44.80  ? 514  ALA A C   1 
ATOM   3904  O  O   . ALA A 1 514 ? 173.775 170.233 219.849 1.00 44.80  ? 514  ALA A O   1 
ATOM   3905  C  CB  . ALA A 1 514 ? 173.924 167.577 221.747 1.00 44.80  ? 514  ALA A CB  1 
ATOM   3906  N  N   . VAL A 1 515 ? 172.611 170.456 221.781 1.00 44.68  ? 515  VAL A N   1 
ATOM   3907  C  CA  . VAL A 1 515 ? 172.685 171.909 221.861 1.00 44.68  ? 515  VAL A CA  1 
ATOM   3908  C  C   . VAL A 1 515 ? 173.182 172.295 223.248 1.00 44.68  ? 515  VAL A C   1 
ATOM   3909  O  O   . VAL A 1 515 ? 172.708 171.759 224.257 1.00 44.68  ? 515  VAL A O   1 
ATOM   3910  C  CB  . VAL A 1 515 ? 171.319 172.563 221.575 1.00 44.68  ? 515  VAL A CB  1 
ATOM   3911  C  CG1 . VAL A 1 515 ? 171.364 174.054 221.864 1.00 44.68  ? 515  VAL A CG1 1 
ATOM   3912  C  CG2 . VAL A 1 515 ? 170.899 172.307 220.138 1.00 44.68  ? 515  VAL A CG2 1 
ATOM   3913  N  N   . ALA A 1 516 ? 174.131 173.227 223.299 1.00 49.26  ? 516  ALA A N   1 
ATOM   3914  C  CA  . ALA A 1 516 ? 174.672 173.730 224.551 1.00 49.26  ? 516  ALA A CA  1 
ATOM   3915  C  C   . ALA A 1 516 ? 174.654 175.251 224.543 1.00 49.26  ? 516  ALA A C   1 
ATOM   3916  O  O   . ALA A 1 516 ? 174.735 175.886 223.489 1.00 49.26  ? 516  ALA A O   1 
ATOM   3917  C  CB  . ALA A 1 516 ? 176.099 173.224 224.790 1.00 49.26  ? 516  ALA A CB  1 
ATOM   3918  N  N   . THR A 1 517 ? 174.528 175.828 225.735 1.00 56.24  ? 517  THR A N   1 
ATOM   3919  C  CA  . THR A 1 517 ? 174.542 177.270 225.924 1.00 56.24  ? 517  THR A CA  1 
ATOM   3920  C  C   . THR A 1 517 ? 175.479 177.626 227.069 1.00 56.24  ? 517  THR A C   1 
ATOM   3921  O  O   . THR A 1 517 ? 175.670 176.844 228.004 1.00 56.24  ? 517  THR A O   1 
ATOM   3922  C  CB  . THR A 1 517 ? 173.141 177.827 226.221 1.00 56.24  ? 517  THR A CB  1 
ATOM   3923  O  OG1 . THR A 1 517 ? 172.629 177.226 227.417 1.00 56.24  ? 517  THR A OG1 1 
ATOM   3924  C  CG2 . THR A 1 517 ? 172.192 177.544 225.068 1.00 56.24  ? 517  THR A CG2 1 
ATOM   3925  N  N   . LYS A 1 518 ? 176.067 178.817 226.979 1.00 67.90  ? 518  LYS A N   1 
ATOM   3926  C  CA  . LYS A 1 518 ? 176.962 179.309 228.015 1.00 67.90  ? 518  LYS A CA  1 
ATOM   3927  C  C   . LYS A 1 518 ? 176.846 180.823 228.094 1.00 67.90  ? 518  LYS A C   1 
ATOM   3928  O  O   . LYS A 1 518 ? 176.550 181.488 227.099 1.00 67.90  ? 518  LYS A O   1 
ATOM   3929  C  CB  . LYS A 1 518 ? 178.413 178.896 227.742 1.00 67.90  ? 518  LYS A CB  1 
ATOM   3930  C  CG  . LYS A 1 518 ? 179.374 179.166 228.887 1.00 67.90  ? 518  LYS A CG  1 
ATOM   3931  C  CD  . LYS A 1 518 ? 180.812 178.928 228.465 1.00 67.90  ? 518  LYS A CD  1 
ATOM   3932  C  CE  . LYS A 1 518 ? 181.780 179.314 229.570 1.00 67.90  ? 518  LYS A CE  1 
ATOM   3933  N  NZ  . LYS A 1 518 ? 183.197 179.151 229.146 1.00 67.90  ? 518  LYS A NZ  1 
ATOM   3934  N  N   . TYR A 1 519 ? 177.083 181.364 229.286 1.00 74.50  ? 519  TYR A N   1 
ATOM   3935  C  CA  . TYR A 1 519 ? 177.041 182.801 229.524 1.00 74.50  ? 519  TYR A CA  1 
ATOM   3936  C  C   . TYR A 1 519 ? 178.444 183.309 229.828 1.00 74.50  ? 519  TYR A C   1 
ATOM   3937  O  O   . TYR A 1 519 ? 179.157 182.722 230.649 1.00 74.50  ? 519  TYR A O   1 
ATOM   3938  C  CB  . TYR A 1 519 ? 176.094 183.140 230.676 1.00 74.50  ? 519  TYR A CB  1 
ATOM   3939  C  CG  . TYR A 1 519 ? 174.632 182.983 230.330 1.00 74.50  ? 519  TYR A CG  1 
ATOM   3940  C  CD1 . TYR A 1 519 ? 173.940 183.997 229.682 1.00 74.50  ? 519  TYR A CD1 1 
ATOM   3941  C  CD2 . TYR A 1 519 ? 173.944 181.821 230.651 1.00 74.50  ? 519  TYR A CD2 1 
ATOM   3942  C  CE1 . TYR A 1 519 ? 172.604 183.859 229.363 1.00 74.50  ? 519  TYR A CE1 1 
ATOM   3943  C  CE2 . TYR A 1 519 ? 172.606 181.673 230.336 1.00 74.50  ? 519  TYR A CE2 1 
ATOM   3944  C  CZ  . TYR A 1 519 ? 171.942 182.695 229.692 1.00 74.50  ? 519  TYR A CZ  1 
ATOM   3945  O  OH  . TYR A 1 519 ? 170.610 182.554 229.376 1.00 74.50  ? 519  TYR A OH  1 
ATOM   3946  N  N   . LEU A 1 520 ? 178.835 184.393 229.165 1.00 80.44  ? 520  LEU A N   1 
ATOM   3947  C  CA  . LEU A 1 520 ? 180.139 185.003 229.350 1.00 80.44  ? 520  LEU A CA  1 
ATOM   3948  C  C   . LEU A 1 520 ? 179.989 186.504 229.540 1.00 80.44  ? 520  LEU A C   1 
ATOM   3949  O  O   . LEU A 1 520 ? 178.993 187.093 229.109 1.00 80.44  ? 520  LEU A O   1 
ATOM   3950  C  CB  . LEU A 1 520 ? 181.058 184.728 228.150 1.00 80.44  ? 520  LEU A CB  1 
ATOM   3951  C  CG  . LEU A 1 520 ? 181.643 183.318 228.032 1.00 80.44  ? 520  LEU A CG  1 
ATOM   3952  C  CD1 . LEU A 1 520 ? 180.707 182.399 227.262 1.00 80.44  ? 520  LEU A CD1 1 
ATOM   3953  C  CD2 . LEU A 1 520 ? 183.017 183.361 227.381 1.00 80.44  ? 520  LEU A CD2 1 
ATOM   3954  N  N   . PRO A 1 521 ? 180.949 187.145 230.205 1.00 85.58  ? 521  PRO A N   1 
ATOM   3955  C  CA  . PRO A 1 521 ? 180.931 188.608 230.287 1.00 85.58  ? 521  PRO A CA  1 
ATOM   3956  C  C   . PRO A 1 521 ? 181.164 189.239 228.924 1.00 85.58  ? 521  PRO A C   1 
ATOM   3957  O  O   . PRO A 1 521 ? 181.818 188.666 228.050 1.00 85.58  ? 521  PRO A O   1 
ATOM   3958  C  CB  . PRO A 1 521 ? 182.079 188.928 231.251 1.00 85.58  ? 521  PRO A CB  1 
ATOM   3959  C  CG  . PRO A 1 521 ? 182.965 187.729 231.202 1.00 85.58  ? 521  PRO A CG  1 
ATOM   3960  C  CD  . PRO A 1 521 ? 182.057 186.560 230.980 1.00 85.58  ? 521  PRO A CD  1 
ATOM   3961  N  N   . ALA A 1 522 ? 180.609 190.437 228.749 1.00 88.17  ? 522  ALA A N   1 
ATOM   3962  C  CA  . ALA A 1 522 ? 180.742 191.142 227.482 1.00 88.17  ? 522  ALA A CA  1 
ATOM   3963  C  C   . ALA A 1 522 ? 182.202 191.477 227.203 1.00 88.17  ? 522  ALA A C   1 
ATOM   3964  O  O   . ALA A 1 522 ? 182.947 191.886 228.097 1.00 88.17  ? 522  ALA A O   1 
ATOM   3965  C  CB  . ALA A 1 522 ? 179.902 192.419 227.494 1.00 88.17  ? 522  ALA A CB  1 
ATOM   3966  N  N   . ARG A 1 523 ? 182.610 191.298 225.948 1.00 85.26  ? 523  ARG A N   1 
ATOM   3967  C  CA  . ARG A 1 523 ? 183.981 191.564 225.544 1.00 85.26  ? 523  ARG A CA  1 
ATOM   3968  C  C   . ARG A 1 523 ? 183.993 192.019 224.093 1.00 85.26  ? 523  ARG A C   1 
ATOM   3969  O  O   . ARG A 1 523 ? 183.062 191.740 223.331 1.00 85.26  ? 523  ARG A O   1 
ATOM   3970  C  CB  . ARG A 1 523 ? 184.871 190.329 225.732 1.00 85.26  ? 523  ARG A CB  1 
ATOM   3971  C  CG  . ARG A 1 523 ? 184.791 189.317 224.602 1.00 85.26  ? 523  ARG A CG  1 
ATOM   3972  C  CD  . ARG A 1 523 ? 185.310 187.960 225.049 1.00 85.26  ? 523  ARG A CD  1 
ATOM   3973  N  NE  . ARG A 1 523 ? 185.696 187.121 223.922 1.00 85.26  ? 523  ARG A NE  1 
ATOM   3974  C  CZ  . ARG A 1 523 ? 186.110 185.866 224.032 1.00 85.26  ? 523  ARG A CZ  1 
ATOM   3975  N  NH1 . ARG A 1 523 ? 186.203 185.270 225.209 1.00 85.26  ? 523  ARG A NH1 1 
ATOM   3976  N  NH2 . ARG A 1 523 ? 186.440 185.193 222.933 1.00 85.26  ? 523  ARG A NH2 1 
ATOM   3977  N  N   . GLU A 1 524 ? 185.057 192.728 223.720 1.00 90.33  ? 524  GLU A N   1 
ATOM   3978  C  CA  . GLU A 1 524 ? 185.172 193.287 222.379 1.00 90.33  ? 524  GLU A CA  1 
ATOM   3979  C  C   . GLU A 1 524 ? 185.842 192.339 221.395 1.00 90.33  ? 524  GLU A C   1 
ATOM   3980  O  O   . GLU A 1 524 ? 185.554 192.402 220.194 1.00 90.33  ? 524  GLU A O   1 
ATOM   3981  C  CB  . GLU A 1 524 ? 185.951 194.605 222.424 1.00 90.33  ? 524  GLU A CB  1 
ATOM   3982  C  CG  . GLU A 1 524 ? 185.238 195.724 223.166 1.00 90.33  ? 524  GLU A CG  1 
ATOM   3983  C  CD  . GLU A 1 524 ? 184.002 196.213 222.437 1.00 90.33  ? 524  GLU A CD  1 
ATOM   3984  O  OE1 . GLU A 1 524 ? 183.995 196.184 221.188 1.00 90.33  ? 524  GLU A OE1 1 
ATOM   3985  O  OE2 . GLU A 1 524 ? 183.037 196.627 223.114 1.00 90.33  ? 524  GLU A OE2 1 
ATOM   3986  N  N   . GLY A 1 525 ? 186.728 191.468 221.872 1.00 85.27  ? 525  GLY A N   1 
ATOM   3987  C  CA  . GLY A 1 525 ? 187.429 190.571 220.981 1.00 85.27  ? 525  GLY A CA  1 
ATOM   3988  C  C   . GLY A 1 525 ? 186.523 189.513 220.382 1.00 85.27  ? 525  GLY A C   1 
ATOM   3989  O  O   . GLY A 1 525 ? 185.492 189.136 220.940 1.00 85.27  ? 525  GLY A O   1 
ATOM   3990  N  N   . ASP A 1 526 ? 186.925 189.031 219.210 1.00 81.89  ? 526  ASP A N   1 
ATOM   3991  C  CA  . ASP A 1 526 ? 186.171 187.989 218.530 1.00 81.89  ? 526  ASP A CA  1 
ATOM   3992  C  C   . ASP A 1 526 ? 186.283 186.667 219.280 1.00 81.89  ? 526  ASP A C   1 
ATOM   3993  O  O   . ASP A 1 526 ? 187.304 186.362 219.902 1.00 81.89  ? 526  ASP A O   1 
ATOM   3994  C  CB  . ASP A 1 526 ? 186.668 187.821 217.094 1.00 81.89  ? 526  ASP A CB  1 
ATOM   3995  C  CG  . ASP A 1 526 ? 186.120 188.881 216.160 1.00 81.89  ? 526  ASP A CG  1 
ATOM   3996  O  OD1 . ASP A 1 526 ? 185.171 189.591 216.555 1.00 81.89  ? 526  ASP A OD1 1 
ATOM   3997  O  OD2 . ASP A 1 526 ? 186.637 189.004 215.030 1.00 81.89  ? 526  ASP A OD2 1 
ATOM   3998  N  N   . TYR A 1 527 ? 185.215 185.879 219.215 1.00 77.29  ? 527  TYR A N   1 
ATOM   3999  C  CA  . TYR A 1 527 ? 185.170 184.587 219.881 1.00 77.29  ? 527  TYR A CA  1 
ATOM   4000  C  C   . TYR A 1 527 ? 185.825 183.521 219.013 1.00 77.29  ? 527  TYR A C   1 
ATOM   4001  O  O   . TYR A 1 527 ? 185.511 183.387 217.827 1.00 77.29  ? 527  TYR A O   1 
ATOM   4002  C  CB  . TYR A 1 527 ? 183.726 184.197 220.200 1.00 77.29  ? 527  TYR A CB  1 
ATOM   4003  C  CG  . TYR A 1 527 ? 183.061 185.116 221.201 1.00 77.29  ? 527  TYR A CG  1 
ATOM   4004  C  CD1 . TYR A 1 527 ? 182.452 186.295 220.794 1.00 77.29  ? 527  TYR A CD1 1 
ATOM   4005  C  CD2 . TYR A 1 527 ? 183.044 184.803 222.554 1.00 77.29  ? 527  TYR A CD2 1 
ATOM   4006  C  CE1 . TYR A 1 527 ? 181.847 187.139 221.705 1.00 77.29  ? 527  TYR A CE1 1 
ATOM   4007  C  CE2 . TYR A 1 527 ? 182.439 185.640 223.472 1.00 77.29  ? 527  TYR A CE2 1 
ATOM   4008  C  CZ  . TYR A 1 527 ? 181.842 186.806 223.042 1.00 77.29  ? 527  TYR A CZ  1 
ATOM   4009  O  OH  . TYR A 1 527 ? 181.238 187.643 223.952 1.00 77.29  ? 527  TYR A OH  1 
ATOM   4010  N  N   . GLN A 1 528 ? 186.740 182.767 219.613 1.00 74.94  ? 528  GLN A N   1 
ATOM   4011  C  CA  . GLN A 1 528 ? 187.481 181.721 218.927 1.00 74.94  ? 528  GLN A CA  1 
ATOM   4012  C  C   . GLN A 1 528 ? 186.947 180.355 219.339 1.00 74.94  ? 528  GLN A C   1 
ATOM   4013  O  O   . GLN A 1 528 ? 186.016 180.239 220.140 1.00 74.94  ? 528  GLN A O   1 
ATOM   4014  C  CB  . GLN A 1 528 ? 188.983 181.817 219.229 1.00 74.94  ? 528  GLN A CB  1 
ATOM   4015  C  CG  . GLN A 1 528 ? 189.511 183.238 219.344 1.00 74.94  ? 528  GLN A CG  1 
ATOM   4016  C  CD  . GLN A 1 528 ? 189.573 183.950 218.008 1.00 74.94  ? 528  GLN A CD  1 
ATOM   4017  O  OE1 . GLN A 1 528 ? 188.918 184.972 217.805 1.00 74.94  ? 528  GLN A OE1 1 
ATOM   4018  N  NE2 . GLN A 1 528 ? 190.367 183.414 217.088 1.00 74.94  ? 528  GLN A NE2 1 
ATOM   4019  N  N   . ARG A 1 529 ? 187.555 179.310 218.774 1.00 72.94  ? 529  ARG A N   1 
ATOM   4020  C  CA  . ARG A 1 529 ? 187.140 177.948 219.092 1.00 72.94  ? 529  ARG A CA  1 
ATOM   4021  C  C   . ARG A 1 529 ? 187.442 177.571 220.535 1.00 72.94  ? 529  ARG A C   1 
ATOM   4022  O  O   . ARG A 1 529 ? 186.845 176.621 221.053 1.00 72.94  ? 529  ARG A O   1 
ATOM   4023  C  CB  . ARG A 1 529 ? 187.819 176.954 218.149 1.00 72.94  ? 529  ARG A CB  1 
ATOM   4024  C  CG  . ARG A 1 529 ? 187.783 177.354 216.686 1.00 72.94  ? 529  ARG A CG  1 
ATOM   4025  C  CD  . ARG A 1 529 ? 188.194 176.193 215.798 1.00 72.94  ? 529  ARG A CD  1 
ATOM   4026  N  NE  . ARG A 1 529 ? 189.306 175.441 216.368 1.00 72.94  ? 529  ARG A NE  1 
ATOM   4027  C  CZ  . ARG A 1 529 ? 189.773 174.303 215.874 1.00 72.94  ? 529  ARG A CZ  1 
ATOM   4028  N  NH1 . ARG A 1 529 ? 189.243 173.746 214.798 1.00 72.94  ? 529  ARG A NH1 1 
ATOM   4029  N  NH2 . ARG A 1 529 ? 190.800 173.708 216.476 1.00 72.94  ? 529  ARG A NH2 1 
ATOM   4030  N  N   . ALA A 1 530 ? 188.353 178.289 221.196 1.00 73.44  ? 530  ALA A N   1 
ATOM   4031  C  CA  . ALA A 1 530 ? 188.700 177.952 222.572 1.00 73.44  ? 530  ALA A CA  1 
ATOM   4032  C  C   . ALA A 1 530 ? 187.583 178.311 223.542 1.00 73.44  ? 530  ALA A C   1 
ATOM   4033  O  O   . ALA A 1 530 ? 187.573 177.825 224.679 1.00 73.44  ? 530  ALA A O   1 
ATOM   4034  C  CB  . ALA A 1 530 ? 189.996 178.653 222.975 1.00 73.44  ? 530  ALA A CB  1 
ATOM   4035  N  N   . ASP A 1 531 ? 186.642 179.151 223.121 1.00 75.24  ? 531  ASP A N   1 
ATOM   4036  C  CA  . ASP A 1 531 ? 185.535 179.564 223.979 1.00 75.24  ? 531  ASP A CA  1 
ATOM   4037  C  C   . ASP A 1 531 ? 184.499 178.470 224.186 1.00 75.24  ? 531  ASP A C   1 
ATOM   4038  O  O   . ASP A 1 531 ? 183.622 178.634 225.043 1.00 75.24  ? 531  ASP A O   1 
ATOM   4039  C  CB  . ASP A 1 531 ? 184.867 180.811 223.399 1.00 75.24  ? 531  ASP A CB  1 
ATOM   4040  C  CG  . ASP A 1 531 ? 185.811 181.995 223.326 1.00 75.24  ? 531  ASP A CG  1 
ATOM   4041  O  OD1 . ASP A 1 531 ? 186.275 182.456 224.390 1.00 75.24  ? 531  ASP A OD1 1 
ATOM   4042  O  OD2 . ASP A 1 531 ? 186.092 182.461 222.202 1.00 75.24  ? 531  ASP A OD2 1 
ATOM   4043  N  N   . GLU A 1 532 ? 184.563 177.369 223.441 1.00 71.28  ? 532  GLU A N   1 
ATOM   4044  C  CA  . GLU A 1 532 ? 183.606 176.274 223.587 1.00 71.28  ? 532  GLU A CA  1 
ATOM   4045  C  C   . GLU A 1 532 ? 184.091 175.310 224.669 1.00 71.28  ? 532  GLU A C   1 
ATOM   4046  O  O   . GLU A 1 532 ? 184.611 174.226 224.402 1.00 71.28  ? 532  GLU A O   1 
ATOM   4047  C  CB  . GLU A 1 532 ? 183.406 175.566 222.251 1.00 71.28  ? 532  GLU A CB  1 
ATOM   4048  C  CG  . GLU A 1 532 ? 182.860 176.457 221.151 1.00 71.28  ? 532  GLU A CG  1 
ATOM   4049  C  CD  . GLU A 1 532 ? 182.764 175.741 219.820 1.00 71.28  ? 532  GLU A CD  1 
ATOM   4050  O  OE1 . GLU A 1 532 ? 183.036 174.522 219.779 1.00 71.28  ? 532  GLU A OE1 1 
ATOM   4051  O  OE2 . GLU A 1 532 ? 182.422 176.396 218.813 1.00 71.28  ? 532  GLU A OE2 1 
ATOM   4052  N  N   . SER A 1 533 ? 183.910 175.734 225.917 1.00 69.48  ? 533  SER A N   1 
ATOM   4053  C  CA  . SER A 1 533 ? 184.315 174.930 227.060 1.00 69.48  ? 533  SER A CA  1 
ATOM   4054  C  C   . SER A 1 533 ? 183.401 175.233 228.237 1.00 69.48  ? 533  SER A C   1 
ATOM   4055  O  O   . SER A 1 533 ? 182.868 176.340 228.358 1.00 69.48  ? 533  SER A O   1 
ATOM   4056  C  CB  . SER A 1 533 ? 185.776 175.192 227.441 1.00 69.48  ? 533  SER A CB  1 
ATOM   4057  O  OG  . SER A 1 533 ? 186.068 176.578 227.410 1.00 69.48  ? 533  SER A OG  1 
ATOM   4058  N  N   . ASP A 1 534 ? 183.234 174.236 229.106 1.00 70.15  ? 534  ASP A N   1 
ATOM   4059  C  CA  . ASP A 1 534 ? 182.398 174.348 230.301 1.00 70.15  ? 534  ASP A CA  1 
ATOM   4060  C  C   . ASP A 1 534 ? 180.981 174.793 229.942 1.00 70.15  ? 534  ASP A C   1 
ATOM   4061  O  O   . ASP A 1 534 ? 180.386 175.658 230.589 1.00 70.15  ? 534  ASP A O   1 
ATOM   4062  C  CB  . ASP A 1 534 ? 183.030 175.295 231.322 1.00 70.15  ? 534  ASP A CB  1 
ATOM   4063  C  CG  . ASP A 1 534 ? 184.363 174.789 231.835 1.00 70.15  ? 534  ASP A CG  1 
ATOM   4064  O  OD1 . ASP A 1 534 ? 184.540 173.556 231.919 1.00 70.15  ? 534  ASP A OD1 1 
ATOM   4065  O  OD2 . ASP A 1 534 ? 185.235 175.625 232.153 1.00 70.15  ? 534  ASP A OD2 1 
ATOM   4066  N  N   . LEU A 1 535 ? 180.442 174.187 228.890 1.00 63.63  ? 535  LEU A N   1 
ATOM   4067  C  CA  . LEU A 1 535 ? 179.126 174.546 228.390 1.00 63.63  ? 535  LEU A CA  1 
ATOM   4068  C  C   . LEU A 1 535 ? 178.032 173.912 229.246 1.00 63.63  ? 535  LEU A C   1 
ATOM   4069  O  O   . LEU A 1 535 ? 178.280 173.040 230.083 1.00 63.63  ? 535  LEU A O   1 
ATOM   4070  C  CB  . LEU A 1 535 ? 178.979 174.114 226.934 1.00 63.63  ? 535  LEU A CB  1 
ATOM   4071  C  CG  . LEU A 1 535 ? 180.013 174.692 225.968 1.00 63.63  ? 535  LEU A CG  1 
ATOM   4072  C  CD1 . LEU A 1 535 ? 179.940 173.985 224.629 1.00 63.63  ? 535  LEU A CD1 1 
ATOM   4073  C  CD2 . LEU A 1 535 ? 179.806 176.183 225.799 1.00 63.63  ? 535  LEU A CD2 1 
ATOM   4074  N  N   . ILE A 1 536 ? 176.801 174.366 229.025 1.00 58.65  ? 536  ILE A N   1 
ATOM   4075  C  CA  . ILE A 1 536 ? 175.620 173.824 229.685 1.00 58.65  ? 536  ILE A CA  1 
ATOM   4076  C  C   . ILE A 1 536 ? 174.776 173.133 228.625 1.00 58.65  ? 536  ILE A C   1 
ATOM   4077  O  O   . ILE A 1 536 ? 174.225 173.793 227.737 1.00 58.65  ? 536  ILE A O   1 
ATOM   4078  C  CB  . ILE A 1 536 ? 174.816 174.920 230.400 1.00 58.65  ? 536  ILE A CB  1 
ATOM   4079  C  CG1 . ILE A 1 536 ? 175.607 175.483 231.581 1.00 58.65  ? 536  ILE A CG1 1 
ATOM   4080  C  CG2 . ILE A 1 536 ? 173.478 174.378 230.868 1.00 58.65  ? 536  ILE A CG2 1 
ATOM   4081  C  CD1 . ILE A 1 536 ? 174.984 176.718 232.196 1.00 58.65  ? 536  ILE A CD1 1 
ATOM   4082  N  N   . LEU A 1 537 ? 174.669 171.809 228.716 1.00 53.95  ? 537  LEU A N   1 
ATOM   4083  C  CA  . LEU A 1 537 ? 173.942 171.027 227.720 1.00 53.95  ? 537  LEU A CA  1 
ATOM   4084  C  C   . LEU A 1 537 ? 172.447 171.209 227.942 1.00 53.95  ? 537  LEU A C   1 
ATOM   4085  O  O   . LEU A 1 537 ? 171.893 170.708 228.926 1.00 53.95  ? 537  LEU A O   1 
ATOM   4086  C  CB  . LEU A 1 537 ? 174.336 169.555 227.809 1.00 53.95  ? 537  LEU A CB  1 
ATOM   4087  C  CG  . LEU A 1 537 ? 173.448 168.553 227.069 1.00 53.95  ? 537  LEU A CG  1 
ATOM   4088  C  CD1 . LEU A 1 537 ? 173.641 168.666 225.565 1.00 53.95  ? 537  LEU A CD1 1 
ATOM   4089  C  CD2 . LEU A 1 537 ? 173.726 167.135 227.544 1.00 53.95  ? 537  LEU A CD2 1 
ATOM   4090  N  N   . GLU A 1 538 ? 171.786 171.933 227.035 1.00 52.52  ? 538  GLU A N   1 
ATOM   4091  C  CA  . GLU A 1 538 ? 170.355 172.162 227.198 1.00 52.52  ? 538  GLU A CA  1 
ATOM   4092  C  C   . GLU A 1 538 ? 169.547 170.916 226.862 1.00 52.52  ? 538  GLU A C   1 
ATOM   4093  O  O   . GLU A 1 538 ? 168.556 170.614 227.536 1.00 52.52  ? 538  GLU A O   1 
ATOM   4094  C  CB  . GLU A 1 538 ? 169.908 173.339 226.331 1.00 52.52  ? 538  GLU A CB  1 
ATOM   4095  C  CG  . GLU A 1 538 ? 170.589 174.659 226.662 1.00 52.52  ? 538  GLU A CG  1 
ATOM   4096  C  CD  . GLU A 1 538 ? 170.014 175.334 227.896 1.00 52.52  ? 538  GLU A CD  1 
ATOM   4097  O  OE1 . GLU A 1 538 ? 169.201 174.706 228.606 1.00 52.52  ? 538  GLU A OE1 1 
ATOM   4098  O  OE2 . GLU A 1 538 ? 170.378 176.500 228.155 1.00 52.52  ? 538  GLU A OE2 1 
ATOM   4099  N  N   . GLY A 1 539 ? 169.952 170.186 225.831 1.00 46.92  ? 539  GLY A N   1 
ATOM   4100  C  CA  . GLY A 1 539 ? 169.245 168.983 225.434 1.00 46.92  ? 539  GLY A CA  1 
ATOM   4101  C  C   . GLY A 1 539 ? 169.645 168.581 224.026 1.00 46.92  ? 539  GLY A C   1 
ATOM   4102  O  O   . GLY A 1 539 ? 170.625 169.082 223.479 1.00 46.92  ? 539  GLY A O   1 
ATOM   4103  N  N   . TYR A 1 540 ? 168.860 167.669 223.458 1.00 41.14  ? 540  TYR A N   1 
ATOM   4104  C  CA  . TYR A 1 540 ? 169.124 167.183 222.113 1.00 41.14  ? 540  TYR A CA  1 
ATOM   4105  C  C   . TYR A 1 540 ? 167.818 167.118 221.338 1.00 41.14  ? 540  TYR A C   1 
ATOM   4106  O  O   . TYR A 1 540 ? 166.741 166.932 221.909 1.00 41.14  ? 540  TYR A O   1 
ATOM   4107  C  CB  . TYR A 1 540 ? 169.809 165.811 222.134 1.00 41.14  ? 540  TYR A CB  1 
ATOM   4108  C  CG  . TYR A 1 540 ? 169.083 164.769 222.951 1.00 41.14  ? 540  TYR A CG  1 
ATOM   4109  C  CD1 . TYR A 1 540 ? 168.037 164.034 222.408 1.00 41.14  ? 540  TYR A CD1 1 
ATOM   4110  C  CD2 . TYR A 1 540 ? 169.444 164.518 224.267 1.00 41.14  ? 540  TYR A CD2 1 
ATOM   4111  C  CE1 . TYR A 1 540 ? 167.371 163.082 223.152 1.00 41.14  ? 540  TYR A CE1 1 
ATOM   4112  C  CE2 . TYR A 1 540 ? 168.784 163.568 225.018 1.00 41.14  ? 540  TYR A CE2 1 
ATOM   4113  C  CZ  . TYR A 1 540 ? 167.749 162.853 224.456 1.00 41.14  ? 540  TYR A CZ  1 
ATOM   4114  O  OH  . TYR A 1 540 ? 167.089 161.905 225.201 1.00 41.14  ? 540  TYR A OH  1 
ATOM   4115  N  N   . ILE A 1 541 ? 167.930 167.268 220.023 1.00 34.83  ? 541  ILE A N   1 
ATOM   4116  C  CA  . ILE A 1 541 ? 166.788 167.229 219.118 1.00 34.83  ? 541  ILE A CA  1 
ATOM   4117  C  C   . ILE A 1 541 ? 166.943 166.009 218.224 1.00 34.83  ? 541  ILE A C   1 
ATOM   4118  O  O   . ILE A 1 541 ? 167.947 165.873 217.515 1.00 34.83  ? 541  ILE A O   1 
ATOM   4119  C  CB  . ILE A 1 541 ? 166.684 168.512 218.281 1.00 34.83  ? 541  ILE A CB  1 
ATOM   4120  C  CG1 . ILE A 1 541 ? 166.572 169.735 219.190 1.00 34.83  ? 541  ILE A CG1 1 
ATOM   4121  C  CG2 . ILE A 1 541 ? 165.495 168.437 217.340 1.00 34.83  ? 541  ILE A CG2 1 
ATOM   4122  C  CD1 . ILE A 1 541 ? 166.391 171.029 218.438 1.00 34.83  ? 541  ILE A CD1 1 
ATOM   4123  N  N   . ALA A 1 542 ? 165.952 165.124 218.255 1.00 35.64  ? 542  ALA A N   1 
ATOM   4124  C  CA  . ALA A 1 542 ? 165.940 163.923 217.432 1.00 35.64  ? 542  ALA A CA  1 
ATOM   4125  C  C   . ALA A 1 542 ? 164.967 164.136 216.283 1.00 35.64  ? 542  ALA A C   1 
ATOM   4126  O  O   . ALA A 1 542 ? 163.807 164.496 216.509 1.00 35.64  ? 542  ALA A O   1 
ATOM   4127  C  CB  . ALA A 1 542 ? 165.547 162.696 218.254 1.00 35.64  ? 542  ALA A CB  1 
ATOM   4128  N  N   . PHE A 1 543 ? 165.437 163.922 215.058 1.00 35.71  ? 543  PHE A N   1 
ATOM   4129  C  CA  . PHE A 1 543 ? 164.622 164.127 213.871 1.00 35.71  ? 543  PHE A CA  1 
ATOM   4130  C  C   . PHE A 1 543 ? 164.759 162.934 212.938 1.00 35.71  ? 543  PHE A C   1 
ATOM   4131  O  O   . PHE A 1 543 ? 165.822 162.314 212.850 1.00 35.71  ? 543  PHE A O   1 
ATOM   4132  C  CB  . PHE A 1 543 ? 165.012 165.418 213.139 1.00 35.71  ? 543  PHE A CB  1 
ATOM   4133  C  CG  . PHE A 1 543 ? 166.478 165.524 212.829 1.00 35.71  ? 543  PHE A CG  1 
ATOM   4134  C  CD1 . PHE A 1 543 ? 167.359 166.065 213.748 1.00 35.71  ? 543  PHE A CD1 1 
ATOM   4135  C  CD2 . PHE A 1 543 ? 166.973 165.096 211.610 1.00 35.71  ? 543  PHE A CD2 1 
ATOM   4136  C  CE1 . PHE A 1 543 ? 168.705 166.163 213.461 1.00 35.71  ? 543  PHE A CE1 1 
ATOM   4137  C  CE2 . PHE A 1 543 ? 168.318 165.197 211.319 1.00 35.71  ? 543  PHE A CE2 1 
ATOM   4138  C  CZ  . PHE A 1 543 ? 169.184 165.733 212.244 1.00 35.71  ? 543  PHE A CZ  1 
ATOM   4139  N  N   . LEU A 1 544 ? 163.673 162.618 212.236 1.00 35.19  ? 544  LEU A N   1 
ATOM   4140  C  CA  . LEU A 1 544 ? 163.633 161.489 211.316 1.00 35.19  ? 544  LEU A CA  1 
ATOM   4141  C  C   . LEU A 1 544 ? 163.696 161.998 209.885 1.00 35.19  ? 544  LEU A C   1 
ATOM   4142  O  O   . LEU A 1 544 ? 162.907 162.867 209.492 1.00 35.19  ? 544  LEU A O   1 
ATOM   4143  C  CB  . LEU A 1 544 ? 162.376 160.645 211.513 1.00 35.19  ? 544  LEU A CB  1 
ATOM   4144  C  CG  . LEU A 1 544 ? 162.269 159.500 210.502 1.00 35.19  ? 544  LEU A CG  1 
ATOM   4145  C  CD1 . LEU A 1 544 ? 163.495 158.603 210.578 1.00 35.19  ? 544  LEU A CD1 1 
ATOM   4146  C  CD2 . LEU A 1 544 ? 161.007 158.696 210.708 1.00 35.19  ? 544  LEU A CD2 1 
ATOM   4147  N  N   . ASP A 1 545 ? 164.633 161.450 209.113 1.00 39.13  ? 545  ASP A N   1 
ATOM   4148  C  CA  . ASP A 1 545 ? 164.781 161.747 207.693 1.00 39.13  ? 545  ASP A CA  1 
ATOM   4149  C  C   . ASP A 1 545 ? 164.340 160.526 206.900 1.00 39.13  ? 545  ASP A C   1 
ATOM   4150  O  O   . ASP A 1 545 ? 165.083 159.534 206.824 1.00 39.13  ? 545  ASP A O   1 
ATOM   4151  C  CB  . ASP A 1 545 ? 166.232 162.110 207.369 1.00 39.13  ? 545  ASP A CB  1 
ATOM   4152  C  CG  . ASP A 1 545 ? 166.389 162.688 205.985 1.00 39.13  ? 545  ASP A CG  1 
ATOM   4153  O  OD1 . ASP A 1 545 ? 165.469 163.401 205.533 1.00 39.13  ? 545  ASP A OD1 1 
ATOM   4154  O  OD2 . ASP A 1 545 ? 167.435 162.435 205.353 1.00 39.13  ? 545  ASP A OD2 1 
ATOM   4155  N  N   . PRO A 1 546 ? 163.157 160.539 206.296 1.00 38.22  ? 546  PRO A N   1 
ATOM   4156  C  CA  . PRO A 1 546 ? 162.619 159.323 205.686 1.00 38.22  ? 546  PRO A CA  1 
ATOM   4157  C  C   . PRO A 1 546 ? 163.318 159.004 204.379 1.00 38.22  ? 546  PRO A C   1 
ATOM   4158  O  O   . PRO A 1 546 ? 163.667 159.913 203.611 1.00 38.22  ? 546  PRO A O   1 
ATOM   4159  C  CB  . PRO A 1 546 ? 161.143 159.670 205.458 1.00 38.22  ? 546  PRO A CB  1 
ATOM   4160  C  CG  . PRO A 1 546 ? 161.134 161.147 205.285 1.00 38.22  ? 546  PRO A CG  1 
ATOM   4161  C  CD  . PRO A 1 546 ? 162.290 161.708 206.072 1.00 38.22  ? 546  PRO A CD  1 
ATOM   4162  N  N   . PRO A 1 547 ? 163.545 157.725 204.092 1.00 37.75  ? 547  PRO A N   1 
ATOM   4163  C  CA  . PRO A 1 547 ? 164.120 157.353 202.796 1.00 37.75  ? 547  PRO A CA  1 
ATOM   4164  C  C   . PRO A 1 547 ? 163.161 157.657 201.658 1.00 37.75  ? 547  PRO A C   1 
ATOM   4165  O  O   . PRO A 1 547 ? 161.938 157.617 201.815 1.00 37.75  ? 547  PRO A O   1 
ATOM   4166  C  CB  . PRO A 1 547 ? 164.363 155.846 202.933 1.00 37.75  ? 547  PRO A CB  1 
ATOM   4167  C  CG  . PRO A 1 547 ? 163.402 155.406 203.985 1.00 37.75  ? 547  PRO A CG  1 
ATOM   4168  C  CD  . PRO A 1 547 ? 163.295 156.552 204.946 1.00 37.75  ? 547  PRO A CD  1 
ATOM   4169  N  N   . LYS A 1 548 ? 163.734 157.970 200.500 1.00 36.35  ? 548  LYS A N   1 
ATOM   4170  C  CA  . LYS A 1 548 ? 162.927 158.255 199.323 1.00 36.35  ? 548  LYS A CA  1 
ATOM   4171  C  C   . LYS A 1 548 ? 162.173 157.007 198.877 1.00 36.35  ? 548  LYS A C   1 
ATOM   4172  O  O   . LYS A 1 548 ? 162.649 155.878 199.024 1.00 36.35  ? 548  LYS A O   1 
ATOM   4173  C  CB  . LYS A 1 548 ? 163.802 158.771 198.183 1.00 36.35  ? 548  LYS A CB  1 
ATOM   4174  C  CG  . LYS A 1 548 ? 163.908 160.282 198.111 1.00 36.35  ? 548  LYS A CG  1 
ATOM   4175  C  CD  . LYS A 1 548 ? 164.778 160.713 196.943 1.00 36.35  ? 548  LYS A CD  1 
ATOM   4176  C  CE  . LYS A 1 548 ? 164.992 162.215 196.938 1.00 36.35  ? 548  LYS A CE  1 
ATOM   4177  N  NZ  . LYS A 1 548 ? 166.017 162.619 195.938 1.00 36.35  ? 548  LYS A NZ  1 
ATOM   4178  N  N   . GLU A 1 549 ? 160.975 157.225 198.332 1.00 41.63  ? 549  GLU A N   1 
ATOM   4179  C  CA  . GLU A 1 549 ? 160.151 156.109 197.881 1.00 41.63  ? 549  GLU A CA  1 
ATOM   4180  C  C   . GLU A 1 549 ? 160.790 155.367 196.714 1.00 41.63  ? 549  GLU A C   1 
ATOM   4181  O  O   . GLU A 1 549 ? 160.594 154.155 196.571 1.00 41.63  ? 549  GLU A O   1 
ATOM   4182  C  CB  . GLU A 1 549 ? 158.760 156.613 197.495 1.00 41.63  ? 549  GLU A CB  1 
ATOM   4183  C  CG  . GLU A 1 549 ? 157.758 155.513 197.195 1.00 41.63  ? 549  GLU A CG  1 
ATOM   4184  C  CD  . GLU A 1 549 ? 157.644 155.220 195.713 1.00 41.63  ? 549  GLU A CD  1 
ATOM   4185  O  OE1 . GLU A 1 549 ? 157.862 156.147 194.904 1.00 41.63  ? 549  GLU A OE1 1 
ATOM   4186  O  OE2 . GLU A 1 549 ? 157.336 154.064 195.356 1.00 41.63  ? 549  GLU A OE2 1 
ATOM   4187  N  N   . THR A 1 550 ? 161.557 156.066 195.880 1.00 39.21  ? 550  THR A N   1 
ATOM   4188  C  CA  . THR A 1 550 ? 162.147 155.486 194.682 1.00 39.21  ? 550  THR A CA  1 
ATOM   4189  C  C   . THR A 1 550 ? 163.578 155.008 194.895 1.00 39.21  ? 550  THR A C   1 
ATOM   4190  O  O   . THR A 1 550 ? 164.231 154.601 193.929 1.00 39.21  ? 550  THR A O   1 
ATOM   4191  C  CB  . THR A 1 550 ? 162.108 156.498 193.535 1.00 39.21  ? 550  THR A CB  1 
ATOM   4192  O  OG1 . THR A 1 550 ? 162.563 157.773 194.004 1.00 39.21  ? 550  THR A OG1 1 
ATOM   4193  C  CG2 . THR A 1 550 ? 160.693 156.640 193.000 1.00 39.21  ? 550  THR A CG2 1 
ATOM   4194  N  N   . THR A 1 551 ? 164.083 155.049 196.130 1.00 38.58  ? 551  THR A N   1 
ATOM   4195  C  CA  . THR A 1 551 ? 165.471 154.665 196.368 1.00 38.58  ? 551  THR A CA  1 
ATOM   4196  C  C   . THR A 1 551 ? 165.685 153.170 196.164 1.00 38.58  ? 551  THR A C   1 
ATOM   4197  O  O   . THR A 1 551 ? 166.654 152.763 195.514 1.00 38.58  ? 551  THR A O   1 
ATOM   4198  C  CB  . THR A 1 551 ? 165.902 155.076 197.775 1.00 38.58  ? 551  THR A CB  1 
ATOM   4199  O  OG1 . THR A 1 551 ? 165.930 156.505 197.869 1.00 38.58  ? 551  THR A OG1 1 
ATOM   4200  C  CG2 . THR A 1 551 ? 167.286 154.535 198.085 1.00 38.58  ? 551  THR A CG2 1 
ATOM   4201  N  N   . ALA A 1 552 ? 164.805 152.338 196.720 1.00 38.91  ? 552  ALA A N   1 
ATOM   4202  C  CA  . ALA A 1 552 ? 164.976 150.891 196.588 1.00 38.91  ? 552  ALA A CA  1 
ATOM   4203  C  C   . ALA A 1 552 ? 164.869 150.405 195.147 1.00 38.91  ? 552  ALA A C   1 
ATOM   4204  O  O   . ALA A 1 552 ? 165.733 149.617 194.723 1.00 38.91  ? 552  ALA A O   1 
ATOM   4205  C  CB  . ALA A 1 552 ? 163.983 150.168 197.505 1.00 38.91  ? 552  ALA A CB  1 
ATOM   4206  N  N   . PRO A 1 553 ? 163.854 150.787 194.356 1.00 38.86  ? 553  PRO A N   1 
ATOM   4207  C  CA  . PRO A 1 553 ? 163.855 150.359 192.946 1.00 38.86  ? 553  PRO A CA  1 
ATOM   4208  C  C   . PRO A 1 553 ? 165.057 150.863 192.169 1.00 38.86  ? 553  PRO A C   1 
ATOM   4209  O  O   . PRO A 1 553 ? 165.581 150.144 191.310 1.00 38.86  ? 553  PRO A O   1 
ATOM   4210  C  CB  . PRO A 1 553 ? 162.540 150.940 192.405 1.00 38.86  ? 553  PRO A CB  1 
ATOM   4211  C  CG  . PRO A 1 553 ? 161.685 151.122 193.604 1.00 38.86  ? 553  PRO A CG  1 
ATOM   4212  C  CD  . PRO A 1 553 ? 162.628 151.536 194.686 1.00 38.86  ? 553  PRO A CD  1 
ATOM   4213  N  N   . ALA A 1 554 ? 165.514 152.085 192.451 1.00 39.41  ? 554  ALA A N   1 
ATOM   4214  C  CA  . ALA A 1 554 ? 166.689 152.609 191.764 1.00 39.41  ? 554  ALA A CA  1 
ATOM   4215  C  C   . ALA A 1 554 ? 167.937 151.812 192.119 1.00 39.41  ? 554  ALA A C   1 
ATOM   4216  O  O   . ALA A 1 554 ? 168.765 151.525 191.247 1.00 39.41  ? 554  ALA A O   1 
ATOM   4217  C  CB  . ALA A 1 554 ? 166.879 154.086 192.100 1.00 39.41  ? 554  ALA A CB  1 
ATOM   4218  N  N   . LEU A 1 555 ? 168.090 151.448 193.393 1.00 39.69  ? 555  LEU A N   1 
ATOM   4219  C  CA  . LEU A 1 555 ? 169.222 150.623 193.799 1.00 39.69  ? 555  LEU A CA  1 
ATOM   4220  C  C   . LEU A 1 555 ? 169.155 149.245 193.156 1.00 39.69  ? 555  LEU A C   1 
ATOM   4221  O  O   . LEU A 1 555 ? 170.182 148.694 192.744 1.00 39.69  ? 555  LEU A O   1 
ATOM   4222  C  CB  . LEU A 1 555 ? 169.265 150.503 195.322 1.00 39.69  ? 555  LEU A CB  1 
ATOM   4223  C  CG  . LEU A 1 555 ? 169.787 151.718 196.091 1.00 39.69  ? 555  LEU A CG  1 
ATOM   4224  C  CD1 . LEU A 1 555 ? 169.723 151.472 197.588 1.00 39.69  ? 555  LEU A CD1 1 
ATOM   4225  C  CD2 . LEU A 1 555 ? 171.204 152.048 195.665 1.00 39.69  ? 555  LEU A CD2 1 
ATOM   4226  N  N   . LYS A 1 556 ? 167.952 148.672 193.065 1.00 39.94  ? 556  LYS A N   1 
ATOM   4227  C  CA  . LYS A 1 556 ? 167.801 147.382 192.400 1.00 39.94  ? 556  LYS A CA  1 
ATOM   4228  C  C   . LYS A 1 556 ? 168.181 147.473 190.928 1.00 39.94  ? 556  LYS A C   1 
ATOM   4229  O  O   . LYS A 1 556 ? 168.869 146.591 190.401 1.00 39.94  ? 556  LYS A O   1 
ATOM   4230  C  CB  . LYS A 1 556 ? 166.367 146.876 192.554 1.00 39.94  ? 556  LYS A CB  1 
ATOM   4231  C  CG  . LYS A 1 556 ? 166.016 146.425 193.961 1.00 39.94  ? 556  LYS A CG  1 
ATOM   4232  C  CD  . LYS A 1 556 ? 164.556 146.020 194.058 1.00 39.94  ? 556  LYS A CD  1 
ATOM   4233  C  CE  . LYS A 1 556 ? 164.152 145.743 195.496 1.00 39.94  ? 556  LYS A CE  1 
ATOM   4234  N  NZ  . LYS A 1 556 ? 162.697 145.453 195.615 1.00 39.94  ? 556  LYS A NZ  1 
ATOM   4235  N  N   . ALA A 1 557 ? 167.748 148.537 190.250 1.00 40.72  ? 557  ALA A N   1 
ATOM   4236  C  CA  . ALA A 1 557 ? 168.102 148.722 188.846 1.00 40.72  ? 557  ALA A CA  1 
ATOM   4237  C  C   . ALA A 1 557 ? 169.606 148.905 188.679 1.00 40.72  ? 557  ALA A C   1 
ATOM   4238  O  O   . ALA A 1 557 ? 170.210 148.371 187.740 1.00 40.72  ? 557  ALA A O   1 
ATOM   4239  C  CB  . ALA A 1 557 ? 167.344 149.916 188.267 1.00 40.72  ? 557  ALA A CB  1 
ATOM   4240  N  N   . LEU A 1 558 ? 170.229 149.670 189.580 1.00 41.50  ? 558  LEU A N   1 
ATOM   4241  C  CA  . LEU A 1 558 ? 171.673 149.863 189.519 1.00 41.50  ? 558  LEU A CA  1 
ATOM   4242  C  C   . LEU A 1 558 ? 172.421 148.553 189.721 1.00 41.50  ? 558  LEU A C   1 
ATOM   4243  O  O   . LEU A 1 558 ? 173.402 148.285 189.019 1.00 41.50  ? 558  LEU A O   1 
ATOM   4244  C  CB  . LEU A 1 558 ? 172.111 150.891 190.562 1.00 41.50  ? 558  LEU A CB  1 
ATOM   4245  C  CG  . LEU A 1 558 ? 171.960 152.361 190.167 1.00 41.50  ? 558  LEU A CG  1 
ATOM   4246  C  CD1 . LEU A 1 558 ? 172.402 153.271 191.300 1.00 41.50  ? 558  LEU A CD1 1 
ATOM   4247  C  CD2 . LEU A 1 558 ? 172.748 152.654 188.904 1.00 41.50  ? 558  LEU A CD2 1 
ATOM   4248  N  N   . LYS A 1 559 ? 171.978 147.730 190.673 1.00 42.43  ? 559  LYS A N   1 
ATOM   4249  C  CA  . LYS A 1 559 ? 172.607 146.428 190.868 1.00 42.43  ? 559  LYS A CA  1 
ATOM   4250  C  C   . LYS A 1 559 ? 172.396 145.527 189.659 1.00 42.43  ? 559  LYS A C   1 
ATOM   4251  O  O   . LYS A 1 559 ? 173.283 144.745 189.299 1.00 42.43  ? 559  LYS A O   1 
ATOM   4252  C  CB  . LYS A 1 559 ? 172.069 145.764 192.133 1.00 42.43  ? 559  LYS A CB  1 
ATOM   4253  C  CG  . LYS A 1 559 ? 172.892 144.572 192.592 1.00 42.43  ? 559  LYS A CG  1 
ATOM   4254  C  CD  . LYS A 1 559 ? 174.351 144.950 192.782 1.00 42.43  ? 559  LYS A CD  1 
ATOM   4255  C  CE  . LYS A 1 559 ? 175.192 143.740 193.152 1.00 42.43  ? 559  LYS A CE  1 
ATOM   4256  N  NZ  . LYS A 1 559 ? 175.154 142.698 192.089 1.00 42.43  ? 559  LYS A NZ  1 
ATOM   4257  N  N   . ALA A 1 560 ? 171.225 145.617 189.025 1.00 42.09  ? 560  ALA A N   1 
ATOM   4258  C  CA  . ALA A 1 560 ? 170.979 144.849 187.808 1.00 42.09  ? 560  ALA A CA  1 
ATOM   4259  C  C   . ALA A 1 560 ? 171.931 145.271 186.697 1.00 42.09  ? 560  ALA A C   1 
ATOM   4260  O  O   . ALA A 1 560 ? 172.438 144.432 185.944 1.00 42.09  ? 560  ALA A O   1 
ATOM   4261  C  CB  . ALA A 1 560 ? 169.525 145.014 187.368 1.00 42.09  ? 560  ALA A CB  1 
ATOM   4262  N  N   . SER A 1 561 ? 172.179 146.577 186.574 1.00 43.20  ? 561  SER A N   1 
ATOM   4263  C  CA  . SER A 1 561 ? 173.154 147.057 185.601 1.00 43.20  ? 561  SER A CA  1 
ATOM   4264  C  C   . SER A 1 561 ? 174.550 146.545 185.931 1.00 43.20  ? 561  SER A C   1 
ATOM   4265  O  O   . SER A 1 561 ? 175.309 146.151 185.038 1.00 43.20  ? 561  SER A O   1 
ATOM   4266  C  CB  . SER A 1 561 ? 173.138 148.585 185.549 1.00 43.20  ? 561  SER A CB  1 
ATOM   4267  O  OG  . SER A 1 561 ? 171.839 149.073 185.266 1.00 43.20  ? 561  SER A OG  1 
ATOM   4268  N  N   . GLY A 1 562 ? 174.905 146.540 187.213 1.00 39.52  ? 562  GLY A N   1 
ATOM   4269  C  CA  . GLY A 1 562 ? 176.206 146.061 187.635 1.00 39.52  ? 562  GLY A CA  1 
ATOM   4270  C  C   . GLY A 1 562 ? 176.995 147.094 188.409 1.00 39.52  ? 562  GLY A C   1 
ATOM   4271  O  O   . GLY A 1 562 ? 178.189 146.910 188.665 1.00 39.52  ? 562  GLY A O   1 
ATOM   4272  N  N   . ILE A 1 563 ? 176.337 148.187 188.790 1.00 39.13  ? 563  ILE A N   1 
ATOM   4273  C  CA  . ILE A 1 563 ? 176.981 149.279 189.512 1.00 39.13  ? 563  ILE A CA  1 
ATOM   4274  C  C   . ILE A 1 563 ? 176.809 149.006 191.003 1.00 39.13  ? 563  ILE A C   1 
ATOM   4275  O  O   . ILE A 1 563 ? 175.732 149.207 191.565 1.00 39.13  ? 563  ILE A O   1 
ATOM   4276  C  CB  . ILE A 1 563 ? 176.403 150.638 189.115 1.00 39.13  ? 563  ILE A CB  1 
ATOM   4277  C  CG1 . ILE A 1 563 ? 176.434 150.806 187.595 1.00 39.13  ? 563  ILE A CG1 1 
ATOM   4278  C  CG2 . ILE A 1 563 ? 177.173 151.759 189.791 1.00 39.13  ? 563  ILE A CG2 1 
ATOM   4279  C  CD1 . ILE A 1 563 ? 176.045 152.190 187.123 1.00 39.13  ? 563  ILE A CD1 1 
ATOM   4280  N  N   . THR A 1 564 ? 177.879 148.545 191.646 1.00 39.96  ? 564  THR A N   1 
ATOM   4281  C  CA  . THR A 1 564 ? 177.855 148.291 193.083 1.00 39.96  ? 564  THR A CA  1 
ATOM   4282  C  C   . THR A 1 564 ? 177.846 149.620 193.827 1.00 39.96  ? 564  THR A C   1 
ATOM   4283  O  O   . THR A 1 564 ? 178.810 150.388 193.755 1.00 39.96  ? 564  THR A O   1 
ATOM   4284  C  CB  . THR A 1 564 ? 179.056 147.446 193.493 1.00 39.96  ? 564  THR A CB  1 
ATOM   4285  O  OG1 . THR A 1 564 ? 179.007 146.184 192.816 1.00 39.96  ? 564  THR A OG1 1 
ATOM   4286  C  CG2 . THR A 1 564 ? 179.051 147.210 194.994 1.00 39.96  ? 564  THR A CG2 1 
ATOM   4287  N  N   . VAL A 1 565 ? 176.762 149.892 194.544 1.00 38.02  ? 565  VAL A N   1 
ATOM   4288  C  CA  . VAL A 1 565 ? 176.591 151.156 195.251 1.00 38.02  ? 565  VAL A CA  1 
ATOM   4289  C  C   . VAL A 1 565 ? 177.235 151.048 196.626 1.00 38.02  ? 565  VAL A C   1 
ATOM   4290  O  O   . VAL A 1 565 ? 176.939 150.123 197.391 1.00 38.02  ? 565  VAL A O   1 
ATOM   4291  C  CB  . VAL A 1 565 ? 175.103 151.523 195.364 1.00 38.02  ? 565  VAL A CB  1 
ATOM   4292  C  CG1 . VAL A 1 565 ? 174.927 152.766 196.218 1.00 38.02  ? 565  VAL A CG1 1 
ATOM   4293  C  CG2 . VAL A 1 565 ? 174.506 151.729 193.984 1.00 38.02  ? 565  VAL A CG2 1 
ATOM   4294  N  N   . LYS A 1 566 ? 178.116 151.993 196.940 1.00 36.92  ? 566  LYS A N   1 
ATOM   4295  C  CA  . LYS A 1 566 ? 178.765 152.077 198.240 1.00 36.92  ? 566  LYS A CA  1 
ATOM   4296  C  C   . LYS A 1 566 ? 178.453 153.427 198.868 1.00 36.92  ? 566  LYS A C   1 
ATOM   4297  O  O   . LYS A 1 566 ? 178.336 154.435 198.166 1.00 36.92  ? 566  LYS A O   1 
ATOM   4298  C  CB  . LYS A 1 566 ? 180.279 151.891 198.117 1.00 36.92  ? 566  LYS A CB  1 
ATOM   4299  C  CG  . LYS A 1 566 ? 180.683 150.632 197.373 1.00 36.92  ? 566  LYS A CG  1 
ATOM   4300  C  CD  . LYS A 1 566 ? 182.111 150.236 197.695 1.00 36.92  ? 566  LYS A CD  1 
ATOM   4301  C  CE  . LYS A 1 566 ? 182.432 148.853 197.153 1.00 36.92  ? 566  LYS A CE  1 
ATOM   4302  N  NZ  . LYS A 1 566 ? 181.382 147.861 197.511 1.00 36.92  ? 566  LYS A NZ  1 
ATOM   4303  N  N   . ILE A 1 567 ? 178.315 153.444 200.190 1.00 37.08  ? 567  ILE A N   1 
ATOM   4304  C  CA  . ILE A 1 567 ? 177.920 154.639 200.925 1.00 37.08  ? 567  ILE A CA  1 
ATOM   4305  C  C   . ILE A 1 567 ? 179.127 155.132 201.710 1.00 37.08  ? 567  ILE A C   1 
ATOM   4306  O  O   . ILE A 1 567 ? 179.670 154.409 202.555 1.00 37.08  ? 567  ILE A O   1 
ATOM   4307  C  CB  . ILE A 1 567 ? 176.730 154.371 201.854 1.00 37.08  ? 567  ILE A CB  1 
ATOM   4308  C  CG1 . ILE A 1 567 ? 175.527 153.879 201.049 1.00 37.08  ? 567  ILE A CG1 1 
ATOM   4309  C  CG2 . ILE A 1 567 ? 176.370 155.626 202.630 1.00 37.08  ? 567  ILE A CG2 1 
ATOM   4310  C  CD1 . ILE A 1 567 ? 174.952 154.919 200.119 1.00 37.08  ? 567  ILE A CD1 1 
ATOM   4311  N  N   . LEU A 1 568 ? 179.549 156.362 201.432 1.00 38.74  ? 568  LEU A N   1 
ATOM   4312  C  CA  . LEU A 1 568 ? 180.589 157.041 202.195 1.00 38.74  ? 568  LEU A CA  1 
ATOM   4313  C  C   . LEU A 1 568 ? 179.949 158.242 202.879 1.00 38.74  ? 568  LEU A C   1 
ATOM   4314  O  O   . LEU A 1 568 ? 179.752 159.287 202.250 1.00 38.74  ? 568  LEU A O   1 
ATOM   4315  C  CB  . LEU A 1 568 ? 181.744 157.472 201.295 1.00 38.74  ? 568  LEU A CB  1 
ATOM   4316  C  CG  . LEU A 1 568 ? 182.383 156.396 200.419 1.00 38.74  ? 568  LEU A CG  1 
ATOM   4317  C  CD1 . LEU A 1 568 ? 183.409 157.014 199.487 1.00 38.74  ? 568  LEU A CD1 1 
ATOM   4318  C  CD2 . LEU A 1 568 ? 183.019 155.326 201.279 1.00 38.74  ? 568  LEU A CD2 1 
ATOM   4319  N  N   . THR A 1 569 ? 179.626 158.095 204.161 1.00 37.69  ? 569  THR A N   1 
ATOM   4320  C  CA  . THR A 1 569 ? 178.920 159.124 204.906 1.00 37.69  ? 569  THR A CA  1 
ATOM   4321  C  C   . THR A 1 569 ? 179.634 159.403 206.219 1.00 37.69  ? 569  THR A C   1 
ATOM   4322  O  O   . THR A 1 569 ? 180.247 158.514 206.814 1.00 37.69  ? 569  THR A O   1 
ATOM   4323  C  CB  . THR A 1 569 ? 177.465 158.721 205.184 1.00 37.69  ? 569  THR A CB  1 
ATOM   4324  O  OG1 . THR A 1 569 ? 176.834 159.725 205.988 1.00 37.69  ? 569  THR A OG1 1 
ATOM   4325  C  CG2 . THR A 1 569 ? 177.406 157.384 205.906 1.00 37.69  ? 569  THR A CG2 1 
ATOM   4326  N  N   . GLY A 1 570 ? 179.556 160.654 206.658 1.00 39.01  ? 570  GLY A N   1 
ATOM   4327  C  CA  . GLY A 1 570 ? 180.131 161.086 207.912 1.00 39.01  ? 570  GLY A CA  1 
ATOM   4328  C  C   . GLY A 1 570 ? 179.207 160.987 209.104 1.00 39.01  ? 570  GLY A C   1 
ATOM   4329  O  O   . GLY A 1 570 ? 179.580 161.422 210.198 1.00 39.01  ? 570  GLY A O   1 
ATOM   4330  N  N   . ASP A 1 571 ? 178.012 160.431 208.929 1.00 42.21  ? 571  ASP A N   1 
ATOM   4331  C  CA  . ASP A 1 571 ? 177.052 160.308 210.011 1.00 42.21  ? 571  ASP A CA  1 
ATOM   4332  C  C   . ASP A 1 571 ? 177.394 159.101 210.883 1.00 42.21  ? 571  ASP A C   1 
ATOM   4333  O  O   . ASP A 1 571 ? 178.365 158.380 210.643 1.00 42.21  ? 571  ASP A O   1 
ATOM   4334  C  CB  . ASP A 1 571 ? 175.635 160.202 209.453 1.00 42.21  ? 571  ASP A CB  1 
ATOM   4335  C  CG  . ASP A 1 571 ? 174.607 160.866 210.345 1.00 42.21  ? 571  ASP A CG  1 
ATOM   4336  O  OD1 . ASP A 1 571 ? 174.909 161.087 211.535 1.00 42.21  ? 571  ASP A OD1 1 
ATOM   4337  O  OD2 . ASP A 1 571 ? 173.497 161.166 209.856 1.00 42.21  ? 571  ASP A OD2 1 
ATOM   4338  N  N   . SER A 1 572 ? 176.584 158.881 211.915 1.00 45.51  ? 572  SER A N   1 
ATOM   4339  C  CA  . SER A 1 572 ? 176.788 157.743 212.799 1.00 45.51  ? 572  SER A CA  1 
ATOM   4340  C  C   . SER A 1 572 ? 176.521 156.436 212.062 1.00 45.51  ? 572  SER A C   1 
ATOM   4341  O  O   . SER A 1 572 ? 175.715 156.375 211.129 1.00 45.51  ? 572  SER A O   1 
ATOM   4342  C  CB  . SER A 1 572 ? 175.881 157.849 214.024 1.00 45.51  ? 572  SER A CB  1 
ATOM   4343  O  OG  . SER A 1 572 ? 176.014 156.710 214.856 1.00 45.51  ? 572  SER A OG  1 
ATOM   4344  N  N   . GLU A 1 573 ? 177.214 155.379 212.490 1.00 44.96  ? 573  GLU A N   1 
ATOM   4345  C  CA  . GLU A 1 573 ? 177.058 154.088 211.830 1.00 44.96  ? 573  GLU A CA  1 
ATOM   4346  C  C   . GLU A 1 573 ? 175.685 153.482 212.088 1.00 44.96  ? 573  GLU A C   1 
ATOM   4347  O  O   . GLU A 1 573 ? 175.179 152.727 211.251 1.00 44.96  ? 573  GLU A O   1 
ATOM   4348  C  CB  . GLU A 1 573 ? 178.163 153.128 212.273 1.00 44.96  ? 573  GLU A CB  1 
ATOM   4349  C  CG  . GLU A 1 573 ? 178.037 152.630 213.701 1.00 44.96  ? 573  GLU A CG  1 
ATOM   4350  C  CD  . GLU A 1 573 ? 178.728 153.539 214.696 1.00 44.96  ? 573  GLU A CD  1 
ATOM   4351  O  OE1 . GLU A 1 573 ? 179.016 154.701 214.340 1.00 44.96  ? 573  GLU A OE1 1 
ATOM   4352  O  OE2 . GLU A 1 573 ? 178.985 153.093 215.834 1.00 44.96  ? 573  GLU A OE2 1 
ATOM   4353  N  N   . LEU A 1 574 ? 175.063 153.802 213.224 1.00 43.88  ? 574  LEU A N   1 
ATOM   4354  C  CA  . LEU A 1 574 ? 173.737 153.265 213.514 1.00 43.88  ? 574  LEU A CA  1 
ATOM   4355  C  C   . LEU A 1 574 ? 172.694 153.835 212.561 1.00 43.88  ? 574  LEU A C   1 
ATOM   4356  O  O   . LEU A 1 574 ? 171.885 153.092 211.991 1.00 43.88  ? 574  LEU A O   1 
ATOM   4357  C  CB  . LEU A 1 574 ? 173.364 153.560 214.966 1.00 43.88  ? 574  LEU A CB  1 
ATOM   4358  C  CG  . LEU A 1 574 ? 174.318 153.006 216.026 1.00 43.88  ? 574  LEU A CG  1 
ATOM   4359  C  CD1 . LEU A 1 574 ? 174.292 153.871 217.275 1.00 43.88  ? 574  LEU A CD1 1 
ATOM   4360  C  CD2 . LEU A 1 574 ? 173.966 151.566 216.364 1.00 43.88  ? 574  LEU A CD2 1 
ATOM   4361  N  N   . VAL A 1 575 ? 172.703 155.156 212.369 1.00 43.87  ? 575  VAL A N   1 
ATOM   4362  C  CA  . VAL A 1 575 ? 171.742 155.788 211.470 1.00 43.87  ? 575  VAL A CA  1 
ATOM   4363  C  C   . VAL A 1 575 ? 171.968 155.327 210.038 1.00 43.87  ? 575  VAL A C   1 
ATOM   4364  O  O   . VAL A 1 575 ? 171.015 155.045 209.302 1.00 43.87  ? 575  VAL A O   1 
ATOM   4365  C  CB  . VAL A 1 575 ? 171.825 157.320 211.588 1.00 43.87  ? 575  VAL A CB  1 
ATOM   4366  C  CG1 . VAL A 1 575 ? 170.730 157.971 210.763 1.00 43.87  ? 575  VAL A CG1 1 
ATOM   4367  C  CG2 . VAL A 1 575 ? 171.732 157.744 213.042 1.00 43.87  ? 575  VAL A CG2 1 
ATOM   4368  N  N   . ALA A 1 576 ? 173.232 155.258 209.614 1.00 44.07  ? 576  ALA A N   1 
ATOM   4369  C  CA  . ALA A 1 576 ? 173.533 154.809 208.260 1.00 44.07  ? 576  ALA A CA  1 
ATOM   4370  C  C   . ALA A 1 576 ? 173.104 153.364 208.048 1.00 44.07  ? 576  ALA A C   1 
ATOM   4371  O  O   . ALA A 1 576 ? 172.555 153.020 206.995 1.00 44.07  ? 576  ALA A O   1 
ATOM   4372  C  CB  . ALA A 1 576 ? 175.024 154.977 207.972 1.00 44.07  ? 576  ALA A CB  1 
ATOM   4373  N  N   . ALA A 1 577 ? 173.345 152.501 209.038 1.00 42.60  ? 577  ALA A N   1 
ATOM   4374  C  CA  . ALA A 1 577 ? 172.921 151.110 208.929 1.00 42.60  ? 577  ALA A CA  1 
ATOM   4375  C  C   . ALA A 1 577 ? 171.404 150.998 208.857 1.00 42.60  ? 577  ALA A C   1 
ATOM   4376  O  O   . ALA A 1 577 ? 170.872 150.211 208.065 1.00 42.60  ? 577  ALA A O   1 
ATOM   4377  C  CB  . ALA A 1 577 ? 173.464 150.301 210.105 1.00 42.60  ? 577  ALA A CB  1 
ATOM   4378  N  N   . LYS A 1 578 ? 170.691 151.774 209.677 1.00 44.35  ? 578  LYS A N   1 
ATOM   4379  C  CA  . LYS A 1 578 ? 169.233 151.746 209.630 1.00 44.35  ? 578  LYS A CA  1 
ATOM   4380  C  C   . LYS A 1 578 ? 168.717 152.225 208.280 1.00 44.35  ? 578  LYS A C   1 
ATOM   4381  O  O   . LYS A 1 578 ? 167.782 151.641 207.722 1.00 44.35  ? 578  LYS A O   1 
ATOM   4382  C  CB  . LYS A 1 578 ? 168.651 152.594 210.759 1.00 44.35  ? 578  LYS A CB  1 
ATOM   4383  C  CG  . LYS A 1 578 ? 167.156 152.835 210.641 1.00 44.35  ? 578  LYS A CG  1 
ATOM   4384  C  CD  . LYS A 1 578 ? 166.374 151.535 210.731 1.00 44.35  ? 578  LYS A CD  1 
ATOM   4385  C  CE  . LYS A 1 578 ? 164.903 151.795 211.014 1.00 44.35  ? 578  LYS A CE  1 
ATOM   4386  N  NZ  . LYS A 1 578 ? 164.228 150.603 211.597 1.00 44.35  ? 578  LYS A NZ  1 
ATOM   4387  N  N   . VAL A 1 579 ? 169.316 153.287 207.737 1.00 44.01  ? 579  VAL A N   1 
ATOM   4388  C  CA  . VAL A 1 579 ? 168.898 153.791 206.431 1.00 44.01  ? 579  VAL A CA  1 
ATOM   4389  C  C   . VAL A 1 579 ? 169.155 152.749 205.349 1.00 44.01  ? 579  VAL A C   1 
ATOM   4390  O  O   . VAL A 1 579 ? 168.306 152.512 204.480 1.00 44.01  ? 579  VAL A O   1 
ATOM   4391  C  CB  . VAL A 1 579 ? 169.611 155.121 206.123 1.00 44.01  ? 579  VAL A CB  1 
ATOM   4392  C  CG1 . VAL A 1 579 ? 169.606 155.398 204.630 1.00 44.01  ? 579  VAL A CG1 1 
ATOM   4393  C  CG2 . VAL A 1 579 ? 168.952 156.260 206.881 1.00 44.01  ? 579  VAL A CG2 1 
ATOM   4394  N  N   . CYS A 1 580 ? 170.325 152.107 205.387 1.00 47.11  ? 580  CYS A N   1 
ATOM   4395  C  CA  . CYS A 1 580 ? 170.647 151.086 204.395 1.00 47.11  ? 580  CYS A CA  1 
ATOM   4396  C  C   . CYS A 1 580 ? 169.687 149.907 204.486 1.00 47.11  ? 580  CYS A C   1 
ATOM   4397  O  O   . CYS A 1 580 ? 169.263 149.361 203.460 1.00 47.11  ? 580  CYS A O   1 
ATOM   4398  C  CB  . CYS A 1 580 ? 172.091 150.621 204.572 1.00 47.11  ? 580  CYS A CB  1 
ATOM   4399  S  SG  . CYS A 1 580 ? 173.327 151.778 203.943 1.00 47.11  ? 580  CYS A SG  1 
ATOM   4400  N  N   . HIS A 1 581 ? 169.341 149.491 205.706 1.00 50.77  ? 581  HIS A N   1 
ATOM   4401  C  CA  . HIS A 1 581 ? 168.371 148.413 205.867 1.00 50.77  ? 581  HIS A CA  1 
ATOM   4402  C  C   . HIS A 1 581 ? 166.994 148.830 205.365 1.00 50.77  ? 581  HIS A C   1 
ATOM   4403  O  O   . HIS A 1 581 ? 166.269 148.018 204.779 1.00 50.77  ? 581  HIS A O   1 
ATOM   4404  C  CB  . HIS A 1 581 ? 168.304 147.984 207.332 1.00 50.77  ? 581  HIS A CB  1 
ATOM   4405  C  CG  . HIS A 1 581 ? 167.179 147.045 207.634 1.00 50.77  ? 581  HIS A CG  1 
ATOM   4406  N  ND1 . HIS A 1 581 ? 166.001 147.460 208.217 1.00 50.77  ? 581  HIS A ND1 1 
ATOM   4407  C  CD2 . HIS A 1 581 ? 167.051 145.713 207.434 1.00 50.77  ? 581  HIS A CD2 1 
ATOM   4408  C  CE1 . HIS A 1 581 ? 165.196 146.423 208.363 1.00 50.77  ? 581  HIS A CE1 1 
ATOM   4409  N  NE2 . HIS A 1 581 ? 165.808 145.351 207.896 1.00 50.77  ? 581  HIS A NE2 1 
ATOM   4410  N  N   . GLU A 1 582 ? 166.613 150.089 205.596 1.00 48.23  ? 582  GLU A N   1 
ATOM   4411  C  CA  . GLU A 1 582 ? 165.326 150.578 205.112 1.00 48.23  ? 582  GLU A CA  1 
ATOM   4412  C  C   . GLU A 1 582 ? 165.267 150.575 203.590 1.00 48.23  ? 582  GLU A C   1 
ATOM   4413  O  O   . GLU A 1 582 ? 164.254 150.180 203.001 1.00 48.23  ? 582  GLU A O   1 
ATOM   4414  C  CB  . GLU A 1 582 ? 165.066 151.983 205.653 1.00 48.23  ? 582  GLU A CB  1 
ATOM   4415  C  CG  . GLU A 1 582 ? 164.540 152.015 207.076 1.00 48.23  ? 582  GLU A CG  1 
ATOM   4416  C  CD  . GLU A 1 582 ? 163.111 151.525 207.177 1.00 48.23  ? 582  GLU A CD  1 
ATOM   4417  O  OE1 . GLU A 1 582 ? 162.323 151.798 206.248 1.00 48.23  ? 582  GLU A OE1 1 
ATOM   4418  O  OE2 . GLU A 1 582 ? 162.775 150.869 208.186 1.00 48.23  ? 582  GLU A OE2 1 
ATOM   4419  N  N   . VAL A 1 583 ? 166.347 151.012 202.932 1.00 44.60  ? 583  VAL A N   1 
ATOM   4420  C  CA  . VAL A 1 583 ? 166.359 151.095 201.474 1.00 44.60  ? 583  VAL A CA  1 
ATOM   4421  C  C   . VAL A 1 583 ? 166.689 149.765 200.815 1.00 44.60  ? 583  VAL A C   1 
ATOM   4422  O  O   . VAL A 1 583 ? 166.702 149.683 199.579 1.00 44.60  ? 583  VAL A O   1 
ATOM   4423  C  CB  . VAL A 1 583 ? 167.354 152.168 200.986 1.00 44.60  ? 583  VAL A CB  1 
ATOM   4424  C  CG1 . VAL A 1 583 ? 167.000 153.523 201.575 1.00 44.60  ? 583  VAL A CG1 1 
ATOM   4425  C  CG2 . VAL A 1 583 ? 168.778 151.774 201.333 1.00 44.60  ? 583  VAL A CG2 1 
ATOM   4426  N  N   . GLY A 1 584 ? 166.956 148.720 201.596 1.00 45.27  ? 584  GLY A N   1 
ATOM   4427  C  CA  . GLY A 1 584 ? 167.228 147.403 201.065 1.00 45.27  ? 584  GLY A CA  1 
ATOM   4428  C  C   . GLY A 1 584 ? 168.690 147.098 200.818 1.00 45.27  ? 584  GLY A C   1 
ATOM   4429  O  O   . GLY A 1 584 ? 169.017 145.950 200.492 1.00 45.27  ? 584  GLY A O   1 
ATOM   4430  N  N   . LEU A 1 585 ? 169.574 148.082 200.957 1.00 46.20  ? 585  LEU A N   1 
ATOM   4431  C  CA  . LEU A 1 585 ? 170.996 147.839 200.766 1.00 46.20  ? 585  LEU A CA  1 
ATOM   4432  C  C   . LEU A 1 585 ? 171.540 146.953 201.881 1.00 46.20  ? 585  LEU A C   1 
ATOM   4433  O  O   . LEU A 1 585 ? 171.104 147.038 203.032 1.00 46.20  ? 585  LEU A O   1 
ATOM   4434  C  CB  . LEU A 1 585 ? 171.760 149.161 200.723 1.00 46.20  ? 585  LEU A CB  1 
ATOM   4435  C  CG  . LEU A 1 585 ? 173.092 149.147 199.974 1.00 46.20  ? 585  LEU A CG  1 
ATOM   4436  C  CD1 . LEU A 1 585 ? 172.884 148.714 198.534 1.00 46.20  ? 585  LEU A CD1 1 
ATOM   4437  C  CD2 . LEU A 1 585 ? 173.762 150.510 200.036 1.00 46.20  ? 585  LEU A CD2 1 
ATOM   4438  N  N   . ASP A 1 586 ? 172.497 146.098 201.532 1.00 53.82  ? 586  ASP A N   1 
ATOM   4439  C  CA  . ASP A 1 586 ? 173.113 145.188 202.492 1.00 53.82  ? 586  ASP A CA  1 
ATOM   4440  C  C   . ASP A 1 586 ? 174.300 145.890 203.142 1.00 53.82  ? 586  ASP A C   1 
ATOM   4441  O  O   . ASP A 1 586 ? 175.363 146.027 202.528 1.00 53.82  ? 586  ASP A O   1 
ATOM   4442  C  CB  . ASP A 1 586 ? 173.548 143.893 201.811 1.00 53.82  ? 586  ASP A CB  1 
ATOM   4443  C  CG  . ASP A 1 586 ? 173.595 142.720 202.770 1.00 53.82  ? 586  ASP A CG  1 
ATOM   4444  O  OD1 . ASP A 1 586 ? 173.109 142.866 203.911 1.00 53.82  ? 586  ASP A OD1 1 
ATOM   4445  O  OD2 . ASP A 1 586 ? 174.119 141.654 202.385 1.00 53.82  ? 586  ASP A OD2 1 
ATOM   4446  N  N   . ALA A 1 587 ? 174.118 146.331 204.389 1.00 51.04  ? 587  ALA A N   1 
ATOM   4447  C  CA  . ALA A 1 587 ? 175.194 147.013 205.097 1.00 51.04  ? 587  ALA A CA  1 
ATOM   4448  C  C   . ALA A 1 587 ? 176.358 146.078 205.394 1.00 51.04  ? 587  ALA A C   1 
ATOM   4449  O  O   . ALA A 1 587 ? 177.519 146.498 205.332 1.00 51.04  ? 587  ALA A O   1 
ATOM   4450  C  CB  . ALA A 1 587 ? 174.665 147.630 206.391 1.00 51.04  ? 587  ALA A CB  1 
ATOM   4451  N  N   . GLY A 1 588 ? 176.075 144.815 205.705 1.00 52.23  ? 588  GLY A N   1 
ATOM   4452  C  CA  . GLY A 1 588 ? 177.143 143.903 206.076 1.00 52.23  ? 588  GLY A CA  1 
ATOM   4453  C  C   . GLY A 1 588 ? 177.823 144.357 207.350 1.00 52.23  ? 588  GLY A C   1 
ATOM   4454  O  O   . GLY A 1 588 ? 177.180 144.597 208.378 1.00 52.23  ? 588  GLY A O   1 
ATOM   4455  N  N   . GLU A 1 589 ? 179.144 144.480 207.287 1.00 53.18  ? 589  GLU A N   1 
ATOM   4456  C  CA  . GLU A 1 589 ? 179.936 144.998 208.394 1.00 53.18  ? 589  GLU A CA  1 
ATOM   4457  C  C   . GLU A 1 589 ? 180.364 146.425 208.077 1.00 53.18  ? 589  GLU A C   1 
ATOM   4458  O  O   . GLU A 1 589 ? 180.836 146.708 206.970 1.00 53.18  ? 589  GLU A O   1 
ATOM   4459  C  CB  . GLU A 1 589 ? 181.147 144.100 208.669 1.00 53.18  ? 589  GLU A CB  1 
ATOM   4460  C  CG  . GLU A 1 589 ? 182.107 143.907 207.500 1.00 53.18  ? 589  GLU A CG  1 
ATOM   4461  C  CD  . GLU A 1 589 ? 183.195 144.961 207.448 1.00 53.18  ? 589  GLU A CD  1 
ATOM   4462  O  OE1 . GLU A 1 589 ? 183.442 145.611 208.485 1.00 53.18  ? 589  GLU A OE1 1 
ATOM   4463  O  OE2 . GLU A 1 589 ? 183.804 145.139 206.372 1.00 53.18  ? 589  GLU A OE2 1 
ATOM   4464  N  N   . VAL A 1 590 ? 180.169 147.321 209.033 1.00 48.94  ? 590  VAL A N   1 
ATOM   4465  C  CA  . VAL A 1 590 ? 180.456 148.737 208.840 1.00 48.94  ? 590  VAL A CA  1 
ATOM   4466  C  C   . VAL A 1 590 ? 181.905 149.013 209.211 1.00 48.94  ? 590  VAL A C   1 
ATOM   4467  O  O   . VAL A 1 590 ? 182.495 148.345 210.067 1.00 48.94  ? 590  VAL A O   1 
ATOM   4468  C  CB  . VAL A 1 590 ? 179.482 149.614 209.656 1.00 48.94  ? 590  VAL A CB  1 
ATOM   4469  C  CG1 . VAL A 1 590 ? 178.046 149.206 209.376 1.00 48.94  ? 590  VAL A CG1 1 
ATOM   4470  C  CG2 . VAL A 1 590 ? 179.784 149.514 211.143 1.00 48.94  ? 590  VAL A CG2 1 
ATOM   4471  N  N   . VAL A 1 591 ? 182.491 150.001 208.541 1.00 48.95  ? 591  VAL A N   1 
ATOM   4472  C  CA  . VAL A 1 591 ? 183.856 150.442 208.799 1.00 48.95  ? 591  VAL A CA  1 
ATOM   4473  C  C   . VAL A 1 591 ? 183.812 151.928 209.120 1.00 48.95  ? 591  VAL A C   1 
ATOM   4474  O  O   . VAL A 1 591 ? 183.321 152.727 208.314 1.00 48.95  ? 591  VAL A O   1 
ATOM   4475  C  CB  . VAL A 1 591 ? 184.784 150.167 207.606 1.00 48.95  ? 591  VAL A CB  1 
ATOM   4476  C  CG1 . VAL A 1 591 ? 186.206 150.570 207.943 1.00 48.95  ? 591  VAL A CG1 1 
ATOM   4477  C  CG2 . VAL A 1 591 ? 184.728 148.699 207.218 1.00 48.95  ? 591  VAL A CG2 1 
ATOM   4478  N  N   . ILE A 1 592 ? 184.318 152.295 210.291 1.00 54.16  ? 592  ILE A N   1 
ATOM   4479  C  CA  . ILE A 1 592 ? 184.357 153.691 210.699 1.00 54.16  ? 592  ILE A CA  1 
ATOM   4480  C  C   . ILE A 1 592 ? 185.678 154.305 210.256 1.00 54.16  ? 592  ILE A C   1 
ATOM   4481  O  O   . ILE A 1 592 ? 186.641 153.607 209.929 1.00 54.16  ? 592  ILE A O   1 
ATOM   4482  C  CB  . ILE A 1 592 ? 184.147 153.847 212.218 1.00 54.16  ? 592  ILE A CB  1 
ATOM   4483  C  CG1 . ILE A 1 592 ? 185.365 153.335 212.986 1.00 54.16  ? 592  ILE A CG1 1 
ATOM   4484  C  CG2 . ILE A 1 592 ? 182.892 153.114 212.660 1.00 54.16  ? 592  ILE A CG2 1 
ATOM   4485  C  CD1 . ILE A 1 592 ? 185.496 153.917 214.376 1.00 54.16  ? 592  ILE A CD1 1 
ATOM   4486  N  N   . GLY A 1 593 ? 185.718 155.639 210.236 1.00 58.27  ? 593  GLY A N   1 
ATOM   4487  C  CA  . GLY A 1 593 ? 186.920 156.331 209.802 1.00 58.27  ? 593  GLY A CA  1 
ATOM   4488  C  C   . GLY A 1 593 ? 188.120 156.066 210.688 1.00 58.27  ? 593  GLY A C   1 
ATOM   4489  O  O   . GLY A 1 593 ? 189.232 155.862 210.192 1.00 58.27  ? 593  GLY A O   1 
ATOM   4490  N  N   . SER A 1 594 ? 187.913 156.031 212.005 1.00 61.94  ? 594  SER A N   1 
ATOM   4491  C  CA  . SER A 1 594 ? 189.023 155.818 212.926 1.00 61.94  ? 594  SER A CA  1 
ATOM   4492  C  C   . SER A 1 594 ? 189.679 154.457 212.733 1.00 61.94  ? 594  SER A C   1 
ATOM   4493  O  O   . SER A 1 594 ? 190.786 154.241 213.236 1.00 61.94  ? 594  SER A O   1 
ATOM   4494  C  CB  . SER A 1 594 ? 188.543 155.966 214.370 1.00 61.94  ? 594  SER A CB  1 
ATOM   4495  O  OG  . SER A 1 594 ? 189.539 155.541 215.284 1.00 61.94  ? 594  SER A OG  1 
ATOM   4496  N  N   . ASP A 1 595 ? 189.025 153.541 212.021 1.00 62.75  ? 595  ASP A N   1 
ATOM   4497  C  CA  . ASP A 1 595 ? 189.567 152.218 211.756 1.00 62.75  ? 595  ASP A CA  1 
ATOM   4498  C  C   . ASP A 1 595 ? 190.249 152.111 210.397 1.00 62.75  ? 595  ASP A C   1 
ATOM   4499  O  O   . ASP A 1 595 ? 190.644 151.009 210.005 1.00 62.75  ? 595  ASP A O   1 
ATOM   4500  C  CB  . ASP A 1 595 ? 188.463 151.165 211.866 1.00 62.75  ? 595  ASP A CB  1 
ATOM   4501  C  CG  . ASP A 1 595 ? 187.925 151.032 213.276 1.00 62.75  ? 595  ASP A CG  1 
ATOM   4502  O  OD1 . ASP A 1 595 ? 188.414 151.754 214.170 1.00 62.75  ? 595  ASP A OD1 1 
ATOM   4503  O  OD2 . ASP A 1 595 ? 187.013 150.206 213.491 1.00 62.75  ? 595  ASP A OD2 1 
ATOM   4504  N  N   . ILE A 1 596 ? 190.397 153.215 209.665 1.00 61.99  ? 596  ILE A N   1 
ATOM   4505  C  CA  . ILE A 1 596 ? 191.126 153.183 208.404 1.00 61.99  ? 596  ILE A CA  1 
ATOM   4506  C  C   . ILE A 1 596 ? 192.420 153.985 208.450 1.00 61.99  ? 596  ILE A C   1 
ATOM   4507  O  O   . ILE A 1 596 ? 193.257 153.823 207.548 1.00 61.99  ? 596  ILE A O   1 
ATOM   4508  C  CB  . ILE A 1 596 ? 190.253 153.656 207.221 1.00 61.99  ? 596  ILE A CB  1 
ATOM   4509  C  CG1 . ILE A 1 596 ? 189.964 155.153 207.316 1.00 61.99  ? 596  ILE A CG1 1 
ATOM   4510  C  CG2 . ILE A 1 596 ? 188.958 152.867 207.166 1.00 61.99  ? 596  ILE A CG2 1 
ATOM   4511  C  CD1 . ILE A 1 596 ? 189.329 155.724 206.072 1.00 61.99  ? 596  ILE A CD1 1 
ATOM   4512  N  N   . GLU A 1 597 ? 192.614 154.842 209.454 1.00 69.13  ? 597  GLU A N   1 
ATOM   4513  C  CA  . GLU A 1 597 ? 193.876 155.566 209.573 1.00 69.13  ? 597  GLU A CA  1 
ATOM   4514  C  C   . GLU A 1 597 ? 195.030 154.609 209.846 1.00 69.13  ? 597  GLU A C   1 
ATOM   4515  O  O   . GLU A 1 597 ? 196.115 154.743 209.269 1.00 69.13  ? 597  GLU A O   1 
ATOM   4516  C  CB  . GLU A 1 597 ? 193.774 156.621 210.675 1.00 69.13  ? 597  GLU A CB  1 
ATOM   4517  C  CG  . GLU A 1 597 ? 192.823 157.761 210.355 1.00 69.13  ? 597  GLU A CG  1 
ATOM   4518  C  CD  . GLU A 1 597 ? 192.809 158.826 211.433 1.00 69.13  ? 597  GLU A CD  1 
ATOM   4519  O  OE1 . GLU A 1 597 ? 193.521 158.658 212.444 1.00 69.13  ? 597  GLU A OE1 1 
ATOM   4520  O  OE2 . GLU A 1 597 ? 192.084 159.830 211.270 1.00 69.13  ? 597  GLU A OE2 1 
ATOM   4521  N  N   . THR A 1 598 ? 194.813 153.634 210.731 1.00 71.17  ? 598  THR A N   1 
ATOM   4522  C  CA  . THR A 1 598 ? 195.858 152.661 211.032 1.00 71.17  ? 598  THR A CA  1 
ATOM   4523  C  C   . THR A 1 598 ? 196.095 151.721 209.856 1.00 71.17  ? 598  THR A C   1 
ATOM   4524  O  O   . THR A 1 598 ? 197.226 151.275 209.631 1.00 71.17  ? 598  THR A O   1 
ATOM   4525  C  CB  . THR A 1 598 ? 195.492 151.866 212.285 1.00 71.17  ? 598  THR A CB  1 
ATOM   4526  O  OG1 . THR A 1 598 ? 194.577 150.819 211.937 1.00 71.17  ? 598  THR A OG1 1 
ATOM   4527  C  CG2 . THR A 1 598 ? 194.849 152.773 213.321 1.00 71.17  ? 598  THR A CG2 1 
ATOM   4528  N  N   . LEU A 1 599 ? 195.045 151.408 209.101 1.00 68.54  ? 599  LEU A N   1 
ATOM   4529  C  CA  . LEU A 1 599 ? 195.177 150.495 207.975 1.00 68.54  ? 599  LEU A CA  1 
ATOM   4530  C  C   . LEU A 1 599 ? 196.035 151.109 206.877 1.00 68.54  ? 599  LEU A C   1 
ATOM   4531  O  O   . LEU A 1 599 ? 195.939 152.303 206.580 1.00 68.54  ? 599  LEU A O   1 
ATOM   4532  C  CB  . LEU A 1 599 ? 193.797 150.134 207.423 1.00 68.54  ? 599  LEU A CB  1 
ATOM   4533  C  CG  . LEU A 1 599 ? 192.929 149.229 208.296 1.00 68.54  ? 599  LEU A CG  1 
ATOM   4534  C  CD1 . LEU A 1 599 ? 191.619 148.912 207.596 1.00 68.54  ? 599  LEU A CD1 1 
ATOM   4535  C  CD2 . LEU A 1 599 ? 193.674 147.951 208.643 1.00 68.54  ? 599  LEU A CD2 1 
ATOM   4536  N  N   . SER A 1 600 ? 196.882 150.280 206.274 1.00 69.74  ? 600  SER A N   1 
ATOM   4537  C  CA  . SER A 1 600 ? 197.723 150.717 205.171 1.00 69.74  ? 600  SER A CA  1 
ATOM   4538  C  C   . SER A 1 600 ? 196.907 150.826 203.890 1.00 69.74  ? 600  SER A C   1 
ATOM   4539  O  O   . SER A 1 600 ? 195.717 150.501 203.855 1.00 69.74  ? 600  SER A O   1 
ATOM   4540  C  CB  . SER A 1 600 ? 198.887 149.748 204.968 1.00 69.74  ? 600  SER A CB  1 
ATOM   4541  O  OG  . SER A 1 600 ? 198.423 148.476 204.550 1.00 69.74  ? 600  SER A OG  1 
ATOM   4542  N  N   . ASP A 1 601 ? 197.563 151.297 202.826 1.00 68.65  ? 601  ASP A N   1 
ATOM   4543  C  CA  . ASP A 1 601 ? 196.897 151.451 201.539 1.00 68.65  ? 601  ASP A CA  1 
ATOM   4544  C  C   . ASP A 1 601 ? 196.400 150.113 201.002 1.00 68.65  ? 601  ASP A C   1 
ATOM   4545  O  O   . ASP A 1 601 ? 195.261 149.997 200.536 1.00 68.65  ? 601  ASP A O   1 
ATOM   4546  C  CB  . ASP A 1 601 ? 197.848 152.113 200.537 1.00 68.65  ? 601  ASP A CB  1 
ATOM   4547  C  CG  . ASP A 1 601 ? 198.212 153.531 200.928 1.00 68.65  ? 601  ASP A CG  1 
ATOM   4548  O  OD1 . ASP A 1 601 ? 197.753 153.992 201.994 1.00 68.65  ? 601  ASP A OD1 1 
ATOM   4549  O  OD2 . ASP A 1 601 ? 198.955 154.186 200.167 1.00 68.65  ? 601  ASP A OD2 1 
ATOM   4550  N  N   . ASP A 1 602 ? 197.251 149.086 201.067 1.00 71.50  ? 602  ASP A N   1 
ATOM   4551  C  CA  . ASP A 1 602 ? 196.863 147.765 200.583 1.00 71.50  ? 602  ASP A CA  1 
ATOM   4552  C  C   . ASP A 1 602 ? 195.713 147.192 201.401 1.00 71.50  ? 602  ASP A C   1 
ATOM   4553  O  O   . ASP A 1 602 ? 194.774 146.606 200.851 1.00 71.50  ? 602  ASP A O   1 
ATOM   4554  C  CB  . ASP A 1 602 ? 198.066 146.822 200.613 1.00 71.50  ? 602  ASP A CB  1 
ATOM   4555  C  CG  . ASP A 1 602 ? 199.048 147.093 199.491 1.00 71.50  ? 602  ASP A CG  1 
ATOM   4556  O  OD1 . ASP A 1 602 ? 198.633 147.050 198.314 1.00 71.50  ? 602  ASP A OD1 1 
ATOM   4557  O  OD2 . ASP A 1 602 ? 200.234 147.348 199.787 1.00 71.50  ? 602  ASP A OD2 1 
ATOM   4558  N  N   . GLU A 1 603 ? 195.775 147.348 202.725 1.00 70.34  ? 603  GLU A N   1 
ATOM   4559  C  CA  . GLU A 1 603 ? 194.718 146.824 203.585 1.00 70.34  ? 603  GLU A CA  1 
ATOM   4560  C  C   . GLU A 1 603 ? 193.387 147.511 203.302 1.00 70.34  ? 603  GLU A C   1 
ATOM   4561  O  O   . GLU A 1 603 ? 192.344 146.855 203.195 1.00 70.34  ? 603  GLU A O   1 
ATOM   4562  C  CB  . GLU A 1 603 ? 195.110 146.991 205.053 1.00 70.34  ? 603  GLU A CB  1 
ATOM   4563  C  CG  . GLU A 1 603 ? 196.276 146.119 205.483 1.00 70.34  ? 603  GLU A CG  1 
ATOM   4564  C  CD  . GLU A 1 603 ? 196.820 146.504 206.843 1.00 70.34  ? 603  GLU A CD  1 
ATOM   4565  O  OE1 . GLU A 1 603 ? 197.317 147.641 206.988 1.00 70.34  ? 603  GLU A OE1 1 
ATOM   4566  O  OE2 . GLU A 1 603 ? 196.751 145.668 207.768 1.00 70.34  ? 603  GLU A OE2 1 
ATOM   4567  N  N   . LEU A 1 604 ? 193.406 148.840 203.174 1.00 65.61  ? 604  LEU A N   1 
ATOM   4568  C  CA  . LEU A 1 604 ? 192.174 149.569 202.892 1.00 65.61  ? 604  LEU A CA  1 
ATOM   4569  C  C   . LEU A 1 604 ? 191.629 149.216 201.514 1.00 65.61  ? 604  LEU A C   1 
ATOM   4570  O  O   . LEU A 1 604 ? 190.412 149.083 201.335 1.00 65.61  ? 604  LEU A O   1 
ATOM   4571  C  CB  . LEU A 1 604 ? 192.411 151.074 203.011 1.00 65.61  ? 604  LEU A CB  1 
ATOM   4572  C  CG  . LEU A 1 604 ? 191.189 151.960 202.764 1.00 65.61  ? 604  LEU A CG  1 
ATOM   4573  C  CD1 . LEU A 1 604 ? 190.018 151.504 203.619 1.00 65.61  ? 604  LEU A CD1 1 
ATOM   4574  C  CD2 . LEU A 1 604 ? 191.515 153.417 203.039 1.00 65.61  ? 604  LEU A CD2 1 
ATOM   4575  N  N   . ALA A 1 605 ? 192.513 149.062 200.526 1.00 65.58  ? 605  ALA A N   1 
ATOM   4576  C  CA  . ALA A 1 605 ? 192.084 148.659 199.193 1.00 65.58  ? 605  ALA A CA  1 
ATOM   4577  C  C   . ALA A 1 605 ? 191.496 147.256 199.167 1.00 65.58  ? 605  ALA A C   1 
ATOM   4578  O  O   . ALA A 1 605 ? 190.542 147.018 198.418 1.00 65.58  ? 605  ALA A O   1 
ATOM   4579  C  CB  . ALA A 1 605 ? 193.255 148.746 198.214 1.00 65.58  ? 605  ALA A CB  1 
ATOM   4580  N  N   . ASN A 1 606 ? 192.034 146.329 199.959 1.00 69.32  ? 606  ASN A N   1 
ATOM   4581  C  CA  . ASN A 1 606 ? 191.467 144.993 200.064 1.00 69.32  ? 606  ASN A CA  1 
ATOM   4582  C  C   . ASN A 1 606 ? 190.208 144.948 200.917 1.00 69.32  ? 606  ASN A C   1 
ATOM   4583  O  O   . ASN A 1 606 ? 189.438 143.988 200.807 1.00 69.32  ? 606  ASN A O   1 
ATOM   4584  C  CB  . ASN A 1 606 ? 192.502 144.021 200.645 1.00 69.32  ? 606  ASN A CB  1 
ATOM   4585  C  CG  . ASN A 1 606 ? 192.208 142.577 200.290 1.00 69.32  ? 606  ASN A CG  1 
ATOM   4586  O  OD1 . ASN A 1 606 ? 192.011 141.738 201.168 1.00 69.32  ? 606  ASN A OD1 1 
ATOM   4587  N  ND2 . ASN A 1 606 ? 192.183 142.280 198.996 1.00 69.32  ? 606  ASN A ND2 1 
ATOM   4588  N  N   . LEU A 1 607 ? 189.983 145.959 201.755 1.00 63.87  ? 607  LEU A N   1 
ATOM   4589  C  CA  . LEU A 1 607 ? 188.780 146.041 202.573 1.00 63.87  ? 607  LEU A CA  1 
ATOM   4590  C  C   . LEU A 1 607 ? 187.635 146.765 201.882 1.00 63.87  ? 607  LEU A C   1 
ATOM   4591  O  O   . LEU A 1 607 ? 186.474 146.386 202.069 1.00 63.87  ? 607  LEU A O   1 
ATOM   4592  C  CB  . LEU A 1 607 ? 189.090 146.746 203.898 1.00 63.87  ? 607  LEU A CB  1 
ATOM   4593  C  CG  . LEU A 1 607 ? 187.936 146.883 204.892 1.00 63.87  ? 607  LEU A CG  1 
ATOM   4594  C  CD1 . LEU A 1 607 ? 187.425 145.515 205.311 1.00 63.87  ? 607  LEU A CD1 1 
ATOM   4595  C  CD2 . LEU A 1 607 ? 188.358 147.699 206.104 1.00 63.87  ? 607  LEU A CD2 1 
ATOM   4596  N  N   . ALA A 1 608 ? 187.932 147.792 201.082 1.00 59.43  ? 608  ALA A N   1 
ATOM   4597  C  CA  . ALA A 1 608 ? 186.891 148.547 200.396 1.00 59.43  ? 608  ALA A CA  1 
ATOM   4598  C  C   . ALA A 1 608 ? 186.226 147.759 199.276 1.00 59.43  ? 608  ALA A C   1 
ATOM   4599  O  O   . ALA A 1 608 ? 185.190 148.199 198.767 1.00 59.43  ? 608  ALA A O   1 
ATOM   4600  C  CB  . ALA A 1 608 ? 187.469 149.849 199.839 1.00 59.43  ? 608  ALA A CB  1 
ATOM   4601  N  N   . GLN A 1 609 ? 186.787 146.619 198.881 1.00 62.58  ? 609  GLN A N   1 
ATOM   4602  C  CA  . GLN A 1 609 ? 186.185 145.781 197.855 1.00 62.58  ? 609  GLN A CA  1 
ATOM   4603  C  C   . GLN A 1 609 ? 185.146 144.817 198.410 1.00 62.58  ? 609  GLN A C   1 
ATOM   4604  O  O   . GLN A 1 609 ? 184.547 144.064 197.635 1.00 62.58  ? 609  GLN A O   1 
ATOM   4605  C  CB  . GLN A 1 609 ? 187.269 144.989 197.114 1.00 62.58  ? 609  GLN A CB  1 
ATOM   4606  C  CG  . GLN A 1 609 ? 188.290 145.853 196.389 1.00 62.58  ? 609  GLN A CG  1 
ATOM   4607  C  CD  . GLN A 1 609 ? 187.748 146.458 195.108 1.00 62.58  ? 609  GLN A CD  1 
ATOM   4608  O  OE1 . GLN A 1 609 ? 186.625 146.171 194.696 1.00 62.58  ? 609  GLN A OE1 1 
ATOM   4609  N  NE2 . GLN A 1 609 ? 188.550 147.304 194.471 1.00 62.58  ? 609  GLN A NE2 1 
ATOM   4610  N  N   . ARG A 1 610 ? 184.920 144.819 199.725 1.00 69.10  ? 610  ARG A N   1 
ATOM   4611  C  CA  . ARG A 1 610 ? 183.952 143.927 200.349 1.00 69.10  ? 610  ARG A CA  1 
ATOM   4612  C  C   . ARG A 1 610 ? 182.967 144.677 201.240 1.00 69.10  ? 610  ARG A C   1 
ATOM   4613  O  O   . ARG A 1 610 ? 181.849 144.194 201.455 1.00 69.10  ? 610  ARG A O   1 
ATOM   4614  C  CB  . ARG A 1 610 ? 184.677 142.842 201.157 1.00 69.10  ? 610  ARG A CB  1 
ATOM   4615  C  CG  . ARG A 1 610 ? 183.770 141.802 201.800 1.00 69.10  ? 610  ARG A CG  1 
ATOM   4616  C  CD  . ARG A 1 610 ? 182.848 141.158 200.778 1.00 69.10  ? 610  ARG A CD  1 
ATOM   4617  N  NE  . ARG A 1 610 ? 181.926 140.212 201.396 1.00 69.10  ? 610  ARG A NE  1 
ATOM   4618  C  CZ  . ARG A 1 610 ? 180.787 139.810 200.850 1.00 69.10  ? 610  ARG A CZ  1 
ATOM   4619  N  NH1 . ARG A 1 610 ? 180.397 140.248 199.664 1.00 69.10  ? 610  ARG A NH1 1 
ATOM   4620  N  NH2 . ARG A 1 610 ? 180.019 138.948 201.510 1.00 69.10  ? 610  ARG A NH2 1 
ATOM   4621  N  N   . THR A 1 611 ? 183.339 145.851 201.742 1.00 52.56  ? 611  THR A N   1 
ATOM   4622  C  CA  . THR A 1 611 ? 182.495 146.639 202.630 1.00 52.56  ? 611  THR A CA  1 
ATOM   4623  C  C   . THR A 1 611 ? 181.589 147.536 201.798 1.00 52.56  ? 611  THR A C   1 
ATOM   4624  O  O   . THR A 1 611 ? 182.047 148.173 200.844 1.00 52.56  ? 611  THR A O   1 
ATOM   4625  C  CB  . THR A 1 611 ? 183.345 147.482 203.584 1.00 52.56  ? 611  THR A CB  1 
ATOM   4626  O  OG1 . THR A 1 611 ? 184.055 146.620 204.482 1.00 52.56  ? 611  THR A OG1 1 
ATOM   4627  C  CG2 . THR A 1 611 ? 182.468 148.427 204.389 1.00 52.56  ? 611  THR A CG2 1 
ATOM   4628  N  N   . THR A 1 612 ? 180.308 147.583 202.161 1.00 44.86  ? 612  THR A N   1 
ATOM   4629  C  CA  . THR A 1 612 ? 179.341 148.390 201.427 1.00 44.86  ? 612  THR A CA  1 
ATOM   4630  C  C   . THR A 1 612 ? 179.091 149.742 202.087 1.00 44.86  ? 612  THR A C   1 
ATOM   4631  O  O   . THR A 1 612 ? 178.964 150.754 201.390 1.00 44.86  ? 612  THR A O   1 
ATOM   4632  C  CB  . THR A 1 612 ? 178.020 147.627 201.286 1.00 44.86  ? 612  THR A CB  1 
ATOM   4633  O  OG1 . THR A 1 612 ? 178.244 146.416 200.555 1.00 44.86  ? 612  THR A OG1 1 
ATOM   4634  C  CG2 . THR A 1 612 ? 176.988 148.468 200.548 1.00 44.86  ? 612  THR A CG2 1 
ATOM   4635  N  N   . LEU A 1 613 ? 179.034 149.788 203.415 1.00 41.68  ? 613  LEU A N   1 
ATOM   4636  C  CA  . LEU A 1 613 ? 178.706 151.007 204.144 1.00 41.68  ? 613  LEU A CA  1 
ATOM   4637  C  C   . LEU A 1 613 ? 179.916 151.461 204.947 1.00 41.68  ? 613  LEU A C   1 
ATOM   4638  O  O   . LEU A 1 613 ? 180.477 150.682 205.726 1.00 41.68  ? 613  LEU A O   1 
ATOM   4639  C  CB  . LEU A 1 613 ? 177.506 150.788 205.066 1.00 41.68  ? 613  LEU A CB  1 
ATOM   4640  C  CG  . LEU A 1 613 ? 177.258 151.884 206.102 1.00 41.68  ? 613  LEU A CG  1 
ATOM   4641  C  CD1 . LEU A 1 613 ? 176.890 153.185 205.411 1.00 41.68  ? 613  LEU A CD1 1 
ATOM   4642  C  CD2 . LEU A 1 613 ? 176.175 151.468 207.080 1.00 41.68  ? 613  LEU A CD2 1 
ATOM   4643  N  N   . PHE A 1 614 ? 180.308 152.717 204.761 1.00 43.34  ? 614  PHE A N   1 
ATOM   4644  C  CA  . PHE A 1 614 ? 181.370 153.349 205.533 1.00 43.34  ? 614  PHE A CA  1 
ATOM   4645  C  C   . PHE A 1 614 ? 180.783 154.533 206.289 1.00 43.34  ? 614  PHE A C   1 
ATOM   4646  O  O   . PHE A 1 614 ? 180.056 155.345 205.707 1.00 43.34  ? 614  PHE A O   1 
ATOM   4647  C  CB  . PHE A 1 614 ? 182.515 153.818 204.630 1.00 43.34  ? 614  PHE A CB  1 
ATOM   4648  C  CG  . PHE A 1 614 ? 183.165 152.718 203.833 1.00 43.34  ? 614  PHE A CG  1 
ATOM   4649  C  CD1 . PHE A 1 614 ? 182.533 152.167 202.730 1.00 43.34  ? 614  PHE A CD1 1 
ATOM   4650  C  CD2 . PHE A 1 614 ? 184.419 152.248 204.181 1.00 43.34  ? 614  PHE A CD2 1 
ATOM   4651  C  CE1 . PHE A 1 614 ? 183.136 151.165 201.997 1.00 43.34  ? 614  PHE A CE1 1 
ATOM   4652  C  CE2 . PHE A 1 614 ? 185.026 151.245 203.452 1.00 43.34  ? 614  PHE A CE2 1 
ATOM   4653  C  CZ  . PHE A 1 614 ? 184.383 150.704 202.359 1.00 43.34  ? 614  PHE A CZ  1 
ATOM   4654  N  N   . ALA A 1 615 ? 181.100 154.636 207.576 1.00 45.11  ? 615  ALA A N   1 
ATOM   4655  C  CA  . ALA A 1 615 ? 180.522 155.657 208.435 1.00 45.11  ? 615  ALA A CA  1 
ATOM   4656  C  C   . ALA A 1 615 ? 181.613 156.457 209.135 1.00 45.11  ? 615  ALA A C   1 
ATOM   4657  O  O   . ALA A 1 615 ? 182.766 156.029 209.224 1.00 45.11  ? 615  ALA A O   1 
ATOM   4658  C  CB  . ALA A 1 615 ? 179.586 155.038 209.477 1.00 45.11  ? 615  ALA A CB  1 
ATOM   4659  N  N   . ARG A 1 616 ? 181.223 157.631 209.632 1.00 46.09  ? 616  ARG A N   1 
ATOM   4660  C  CA  . ARG A 1 616 ? 182.119 158.533 210.356 1.00 46.09  ? 616  ARG A CA  1 
ATOM   4661  C  C   . ARG A 1 616 ? 183.384 158.819 209.551 1.00 46.09  ? 616  ARG A C   1 
ATOM   4662  O  O   . ARG A 1 616 ? 184.507 158.581 209.999 1.00 46.09  ? 616  ARG A O   1 
ATOM   4663  C  CB  . ARG A 1 616 ? 182.463 157.974 211.737 1.00 46.09  ? 616  ARG A CB  1 
ATOM   4664  C  CG  . ARG A 1 616 ? 181.341 158.105 212.749 1.00 46.09  ? 616  ARG A CG  1 
ATOM   4665  C  CD  . ARG A 1 616 ? 181.875 158.045 214.169 1.00 46.09  ? 616  ARG A CD  1 
ATOM   4666  N  NE  . ARG A 1 616 ? 180.809 158.142 215.158 1.00 46.09  ? 616  ARG A NE  1 
ATOM   4667  C  CZ  . ARG A 1 616 ? 180.282 157.105 215.794 1.00 46.09  ? 616  ARG A CZ  1 
ATOM   4668  N  NH1 . ARG A 1 616 ? 180.702 155.871 215.569 1.00 46.09  ? 616  ARG A NH1 1 
ATOM   4669  N  NH2 . ARG A 1 616 ? 179.312 157.311 216.680 1.00 46.09  ? 616  ARG A NH2 1 
ATOM   4670  N  N   . LEU A 1 617 ? 183.191 159.340 208.344 1.00 45.61  ? 617  LEU A N   1 
ATOM   4671  C  CA  . LEU A 1 617 ? 184.284 159.592 207.418 1.00 45.61  ? 617  LEU A CA  1 
ATOM   4672  C  C   . LEU A 1 617 ? 184.554 161.086 207.309 1.00 45.61  ? 617  LEU A C   1 
ATOM   4673  O  O   . LEU A 1 617 ? 183.628 161.877 207.105 1.00 45.61  ? 617  LEU A O   1 
ATOM   4674  C  CB  . LEU A 1 617 ? 183.966 159.023 206.036 1.00 45.61  ? 617  LEU A CB  1 
ATOM   4675  C  CG  . LEU A 1 617 ? 183.897 157.504 205.906 1.00 45.61  ? 617  LEU A CG  1 
ATOM   4676  C  CD1 . LEU A 1 617 ? 183.808 157.122 204.443 1.00 45.61  ? 617  LEU A CD1 1 
ATOM   4677  C  CD2 . LEU A 1 617 ? 185.101 156.851 206.561 1.00 45.61  ? 617  LEU A CD2 1 
ATOM   4678  N  N   . THR A 1 618 ? 185.818 161.462 207.450 1.00 52.03  ? 618  THR A N   1 
ATOM   4679  C  CA  . THR A 1 618 ? 186.256 162.803 207.113 1.00 52.03  ? 618  THR A CA  1 
ATOM   4680  C  C   . THR A 1 618 ? 186.458 162.910 205.604 1.00 52.03  ? 618  THR A C   1 
ATOM   4681  O  O   . THR A 1 618 ? 186.596 161.895 204.917 1.00 52.03  ? 618  THR A O   1 
ATOM   4682  C  CB  . THR A 1 618 ? 187.550 163.135 207.851 1.00 52.03  ? 618  THR A CB  1 
ATOM   4683  O  OG1 . THR A 1 618 ? 188.579 162.222 207.451 1.00 52.03  ? 618  THR A OG1 1 
ATOM   4684  C  CG2 . THR A 1 618 ? 187.343 163.031 209.352 1.00 52.03  ? 618  THR A CG2 1 
ATOM   4685  N  N   . PRO A 1 619 ? 186.457 164.129 205.056 1.00 52.77  ? 619  PRO A N   1 
ATOM   4686  C  CA  . PRO A 1 619 ? 186.679 164.270 203.607 1.00 52.77  ? 619  PRO A CA  1 
ATOM   4687  C  C   . PRO A 1 619 ? 187.977 163.647 203.126 1.00 52.77  ? 619  PRO A C   1 
ATOM   4688  O  O   . PRO A 1 619 ? 188.020 163.107 202.012 1.00 52.77  ? 619  PRO A O   1 
ATOM   4689  C  CB  . PRO A 1 619 ? 186.670 165.791 203.408 1.00 52.77  ? 619  PRO A CB  1 
ATOM   4690  C  CG  . PRO A 1 619 ? 185.781 166.285 204.496 1.00 52.77  ? 619  PRO A CG  1 
ATOM   4691  C  CD  . PRO A 1 619 ? 186.080 165.410 205.679 1.00 52.77  ? 619  PRO A CD  1 
ATOM   4692  N  N   . MET A 1 620 ? 189.039 163.700 203.934 1.00 57.44  ? 620  MET A N   1 
ATOM   4693  C  CA  . MET A 1 620 ? 190.272 163.008 203.573 1.00 57.44  ? 620  MET A CA  1 
ATOM   4694  C  C   . MET A 1 620 ? 190.048 161.503 203.486 1.00 57.44  ? 620  MET A C   1 
ATOM   4695  O  O   . MET A 1 620 ? 190.575 160.839 202.585 1.00 57.44  ? 620  MET A O   1 
ATOM   4696  C  CB  . MET A 1 620 ? 191.371 163.332 204.583 1.00 57.44  ? 620  MET A CB  1 
ATOM   4697  C  CG  . MET A 1 620 ? 191.496 164.810 204.915 1.00 57.44  ? 620  MET A CG  1 
ATOM   4698  S  SD  . MET A 1 620 ? 192.415 165.741 203.674 1.00 57.44  ? 620  MET A SD  1 
ATOM   4699  C  CE  . MET A 1 620 ? 191.079 166.524 202.774 1.00 57.44  ? 620  MET A CE  1 
ATOM   4700  N  N   . HIS A 1 621 ? 189.270 160.947 204.419 1.00 53.20  ? 621  HIS A N   1 
ATOM   4701  C  CA  . HIS A 1 621 ? 188.954 159.523 204.367 1.00 53.20  ? 621  HIS A CA  1 
ATOM   4702  C  C   . HIS A 1 621 ? 188.166 159.179 203.111 1.00 53.20  ? 621  HIS A C   1 
ATOM   4703  O  O   . HIS A 1 621 ? 188.416 158.148 202.475 1.00 53.20  ? 621  HIS A O   1 
ATOM   4704  C  CB  . HIS A 1 621 ? 188.175 159.112 205.616 1.00 53.20  ? 621  HIS A CB  1 
ATOM   4705  C  CG  . HIS A 1 621 ? 188.948 159.263 206.888 1.00 53.20  ? 621  HIS A CG  1 
ATOM   4706  N  ND1 . HIS A 1 621 ? 188.341 159.494 208.103 1.00 53.20  ? 621  HIS A ND1 1 
ATOM   4707  C  CD2 . HIS A 1 621 ? 190.278 159.214 207.135 1.00 53.20  ? 621  HIS A CD2 1 
ATOM   4708  C  CE1 . HIS A 1 621 ? 189.264 159.582 209.044 1.00 53.20  ? 621  HIS A CE1 1 
ATOM   4709  N  NE2 . HIS A 1 621 ? 190.448 159.415 208.483 1.00 53.20  ? 621  HIS A NE2 1 
ATOM   4710  N  N   . LYS A 1 622 ? 187.203 160.027 202.743 1.00 47.90  ? 622  LYS A N   1 
ATOM   4711  C  CA  . LYS A 1 622 ? 186.440 159.799 201.520 1.00 47.90  ? 622  LYS A CA  1 
ATOM   4712  C  C   . LYS A 1 622 ? 187.350 159.819 200.300 1.00 47.90  ? 622  LYS A C   1 
ATOM   4713  O  O   . LYS A 1 622 ? 187.247 158.957 199.418 1.00 47.90  ? 622  LYS A O   1 
ATOM   4714  C  CB  . LYS A 1 622 ? 185.341 160.853 201.383 1.00 47.90  ? 622  LYS A CB  1 
ATOM   4715  C  CG  . LYS A 1 622 ? 184.263 160.785 202.447 1.00 47.90  ? 622  LYS A CG  1 
ATOM   4716  C  CD  . LYS A 1 622 ? 182.964 161.384 201.938 1.00 47.90  ? 622  LYS A CD  1 
ATOM   4717  C  CE  . LYS A 1 622 ? 182.178 162.035 203.061 1.00 47.90  ? 622  LYS A CE  1 
ATOM   4718  N  NZ  . LYS A 1 622 ? 180.823 162.462 202.616 1.00 47.90  ? 622  LYS A NZ  1 
ATOM   4719  N  N   . GLU A 1 623 ? 188.253 160.801 200.237 1.00 53.85  ? 623  GLU A N   1 
ATOM   4720  C  CA  . GLU A 1 623 ? 189.172 160.885 199.107 1.00 53.85  ? 623  GLU A CA  1 
ATOM   4721  C  C   . GLU A 1 623 ? 190.066 159.654 199.032 1.00 53.85  ? 623  GLU A C   1 
ATOM   4722  O  O   . GLU A 1 623 ? 190.279 159.100 197.948 1.00 53.85  ? 623  GLU A O   1 
ATOM   4723  C  CB  . GLU A 1 623 ? 190.016 162.155 199.209 1.00 53.85  ? 623  GLU A CB  1 
ATOM   4724  C  CG  . GLU A 1 623 ? 191.216 162.175 198.279 1.00 53.85  ? 623  GLU A CG  1 
ATOM   4725  C  CD  . GLU A 1 623 ? 192.102 163.385 198.497 1.00 53.85  ? 623  GLU A CD  1 
ATOM   4726  O  OE1 . GLU A 1 623 ? 192.026 163.992 199.585 1.00 53.85  ? 623  GLU A OE1 1 
ATOM   4727  O  OE2 . GLU A 1 623 ? 192.879 163.728 197.580 1.00 53.85  ? 623  GLU A OE2 1 
ATOM   4728  N  N   . ARG A 1 624 ? 190.589 159.205 200.175 1.00 58.01  ? 624  ARG A N   1 
ATOM   4729  C  CA  . ARG A 1 624 ? 191.450 158.026 200.180 1.00 58.01  ? 624  ARG A CA  1 
ATOM   4730  C  C   . ARG A 1 624 ? 190.689 156.780 199.743 1.00 58.01  ? 624  ARG A C   1 
ATOM   4731  O  O   . ARG A 1 624 ? 191.196 155.983 198.944 1.00 58.01  ? 624  ARG A O   1 
ATOM   4732  C  CB  . ARG A 1 624 ? 192.055 157.824 201.568 1.00 58.01  ? 624  ARG A CB  1 
ATOM   4733  C  CG  . ARG A 1 624 ? 193.054 156.683 201.644 1.00 58.01  ? 624  ARG A CG  1 
ATOM   4734  C  CD  . ARG A 1 624 ? 193.587 156.511 203.056 1.00 58.01  ? 624  ARG A CD  1 
ATOM   4735  N  NE  . ARG A 1 624 ? 194.322 155.262 203.213 1.00 58.01  ? 624  ARG A NE  1 
ATOM   4736  C  CZ  . ARG A 1 624 ? 194.659 154.734 204.382 1.00 58.01  ? 624  ARG A CZ  1 
ATOM   4737  N  NH1 . ARG A 1 624 ? 194.345 155.324 205.523 1.00 58.01  ? 624  ARG A NH1 1 
ATOM   4738  N  NH2 . ARG A 1 624 ? 195.328 153.584 204.405 1.00 58.01  ? 624  ARG A NH2 1 
ATOM   4739  N  N   . ILE A 1 625 ? 189.469 156.597 200.255 1.00 50.01  ? 625  ILE A N   1 
ATOM   4740  C  CA  . ILE A 1 625 ? 188.683 155.419 199.898 1.00 50.01  ? 625  ILE A CA  1 
ATOM   4741  C  C   . ILE A 1 625 ? 188.361 155.423 198.410 1.00 50.01  ? 625  ILE A C   1 
ATOM   4742  O  O   . ILE A 1 625 ? 188.447 154.388 197.738 1.00 50.01  ? 625  ILE A O   1 
ATOM   4743  C  CB  . ILE A 1 625 ? 187.409 155.344 200.759 1.00 50.01  ? 625  ILE A CB  1 
ATOM   4744  C  CG1 . ILE A 1 625 ? 187.747 154.853 202.167 1.00 50.01  ? 625  ILE A CG1 1 
ATOM   4745  C  CG2 . ILE A 1 625 ? 186.381 154.429 200.118 1.00 50.01  ? 625  ILE A CG2 1 
ATOM   4746  C  CD1 . ILE A 1 625 ? 186.762 155.300 203.222 1.00 50.01  ? 625  ILE A CD1 1 
ATOM   4747  N  N   . VAL A 1 626 ? 187.990 156.586 197.869 1.00 47.02  ? 626  VAL A N   1 
ATOM   4748  C  CA  . VAL A 1 626 ? 187.700 156.676 196.441 1.00 47.02  ? 626  VAL A CA  1 
ATOM   4749  C  C   . VAL A 1 626 ? 188.952 156.392 195.619 1.00 47.02  ? 626  VAL A C   1 
ATOM   4750  O  O   . VAL A 1 626 ? 188.897 155.688 194.603 1.00 47.02  ? 626  VAL A O   1 
ATOM   4751  C  CB  . VAL A 1 626 ? 187.098 158.052 196.105 1.00 47.02  ? 626  VAL A CB  1 
ATOM   4752  C  CG1 . VAL A 1 626 ? 187.017 158.238 194.608 1.00 47.02  ? 626  VAL A CG1 1 
ATOM   4753  C  CG2 . VAL A 1 626 ? 185.721 158.184 196.725 1.00 47.02  ? 626  VAL A CG2 1 
ATOM   4754  N  N   . THR A 1 627 ? 190.099 156.928 196.044 1.00 49.76  ? 627  THR A N   1 
ATOM   4755  C  CA  . THR A 1 627 ? 191.338 156.711 195.305 1.00 49.76  ? 627  THR A CA  1 
ATOM   4756  C  C   . THR A 1 627 ? 191.726 155.238 195.287 1.00 49.76  ? 627  THR A C   1 
ATOM   4757  O  O   . THR A 1 627 ? 192.144 154.711 194.250 1.00 49.76  ? 627  THR A O   1 
ATOM   4758  C  CB  . THR A 1 627 ? 192.464 157.551 195.907 1.00 49.76  ? 627  THR A CB  1 
ATOM   4759  O  OG1 . THR A 1 627 ? 192.101 158.936 195.871 1.00 49.76  ? 627  THR A OG1 1 
ATOM   4760  C  CG2 . THR A 1 627 ? 193.756 157.352 195.129 1.00 49.76  ? 627  THR A CG2 1 
ATOM   4761  N  N   . LEU A 1 628 ? 191.585 154.552 196.421 1.00 53.24  ? 628  LEU A N   1 
ATOM   4762  C  CA  . LEU A 1 628 ? 191.998 153.157 196.498 1.00 53.24  ? 628  LEU A CA  1 
ATOM   4763  C  C   . LEU A 1 628 ? 190.978 152.195 195.902 1.00 53.24  ? 628  LEU A C   1 
ATOM   4764  O  O   . LEU A 1 628 ? 191.249 150.991 195.845 1.00 53.24  ? 628  LEU A O   1 
ATOM   4765  C  CB  . LEU A 1 628 ? 192.282 152.767 197.950 1.00 53.24  ? 628  LEU A CB  1 
ATOM   4766  C  CG  . LEU A 1 628 ? 193.330 153.611 198.679 1.00 53.24  ? 628  LEU A CG  1 
ATOM   4767  C  CD1 . LEU A 1 628 ? 193.611 153.046 200.060 1.00 53.24  ? 628  LEU A CD1 1 
ATOM   4768  C  CD2 . LEU A 1 628 ? 194.612 153.711 197.868 1.00 53.24  ? 628  LEU A CD2 1 
ATOM   4769  N  N   . LEU A 1 629 ? 189.819 152.686 195.463 1.00 47.24  ? 629  LEU A N   1 
ATOM   4770  C  CA  . LEU A 1 629 ? 188.805 151.818 194.879 1.00 47.24  ? 629  LEU A CA  1 
ATOM   4771  C  C   . LEU A 1 629 ? 188.956 151.644 193.373 1.00 47.24  ? 629  LEU A C   1 
ATOM   4772  O  O   . LEU A 1 629 ? 188.242 150.820 192.791 1.00 47.24  ? 629  LEU A O   1 
ATOM   4773  C  CB  . LEU A 1 629 ? 187.408 152.359 195.189 1.00 47.24  ? 629  LEU A CB  1 
ATOM   4774  C  CG  . LEU A 1 629 ? 186.702 151.761 196.405 1.00 47.24  ? 629  LEU A CG  1 
ATOM   4775  C  CD1 . LEU A 1 629 ? 185.345 152.412 196.612 1.00 47.24  ? 629  LEU A CD1 1 
ATOM   4776  C  CD2 . LEU A 1 629 ? 186.562 150.258 196.249 1.00 47.24  ? 629  LEU A CD2 1 
ATOM   4777  N  N   . LYS A 1 630 ? 189.854 152.390 192.728 1.00 47.33  ? 630  LYS A N   1 
ATOM   4778  C  CA  . LYS A 1 630 ? 189.999 152.329 191.279 1.00 47.33  ? 630  LYS A CA  1 
ATOM   4779  C  C   . LYS A 1 630 ? 191.173 151.478 190.816 1.00 47.33  ? 630  LYS A C   1 
ATOM   4780  O  O   . LYS A 1 630 ? 191.244 151.151 189.627 1.00 47.33  ? 630  LYS A O   1 
ATOM   4781  C  CB  . LYS A 1 630 ? 190.163 153.739 190.697 1.00 47.33  ? 630  LYS A CB  1 
ATOM   4782  C  CG  . LYS A 1 630 ? 189.369 154.813 191.415 1.00 47.33  ? 630  LYS A CG  1 
ATOM   4783  C  CD  . LYS A 1 630 ? 189.602 156.178 190.791 1.00 47.33  ? 630  LYS A CD  1 
ATOM   4784  C  CE  . LYS A 1 630 ? 191.084 156.503 190.708 1.00 47.33  ? 630  LYS A CE  1 
ATOM   4785  N  NZ  . LYS A 1 630 ? 191.322 157.854 190.130 1.00 47.33  ? 630  LYS A NZ  1 
ATOM   4786  N  N   . ARG A 1 631 ? 192.092 151.120 191.715 1.00 55.12  ? 631  ARG A N   1 
ATOM   4787  C  CA  . ARG A 1 631 ? 193.324 150.458 191.296 1.00 55.12  ? 631  ARG A CA  1 
ATOM   4788  C  C   . ARG A 1 631 ? 193.050 149.084 190.695 1.00 55.12  ? 631  ARG A C   1 
ATOM   4789  O  O   . ARG A 1 631 ? 193.683 148.687 189.710 1.00 55.12  ? 631  ARG A O   1 
ATOM   4790  C  CB  . ARG A 1 631 ? 194.290 150.350 192.477 1.00 55.12  ? 631  ARG A CB  1 
ATOM   4791  C  CG  . ARG A 1 631 ? 193.647 149.928 193.785 1.00 55.12  ? 631  ARG A CG  1 
ATOM   4792  C  CD  . ARG A 1 631 ? 194.482 150.389 194.966 1.00 55.12  ? 631  ARG A CD  1 
ATOM   4793  N  NE  . ARG A 1 631 ? 195.907 150.199 194.723 1.00 55.12  ? 631  ARG A NE  1 
ATOM   4794  C  CZ  . ARG A 1 631 ? 196.870 150.661 195.508 1.00 55.12  ? 631  ARG A CZ  1 
ATOM   4795  N  NH1 . ARG A 1 631 ? 196.597 151.351 196.603 1.00 55.12  ? 631  ARG A NH1 1 
ATOM   4796  N  NH2 . ARG A 1 631 ? 198.138 150.425 195.187 1.00 55.12  ? 631  ARG A NH2 1 
ATOM   4797  N  N   . GLU A 1 632 ? 192.106 148.340 191.272 1.00 57.40  ? 632  GLU A N   1 
ATOM   4798  C  CA  . GLU A 1 632 ? 191.834 146.971 190.833 1.00 57.40  ? 632  GLU A CA  1 
ATOM   4799  C  C   . GLU A 1 632 ? 190.880 146.964 189.634 1.00 57.40  ? 632  GLU A C   1 
ATOM   4800  O  O   . GLU A 1 632 ? 189.849 146.293 189.616 1.00 57.40  ? 632  GLU A O   1 
ATOM   4801  C  CB  . GLU A 1 632 ? 191.286 146.149 191.993 1.00 57.40  ? 632  GLU A CB  1 
ATOM   4802  C  CG  . GLU A 1 632 ? 191.560 144.653 191.886 1.00 57.40  ? 632  GLU A CG  1 
ATOM   4803  C  CD  . GLU A 1 632 ? 190.403 143.879 191.286 1.00 57.40  ? 632  GLU A CD  1 
ATOM   4804  O  OE1 . GLU A 1 632 ? 189.240 144.278 191.505 1.00 57.40  ? 632  GLU A OE1 1 
ATOM   4805  O  OE2 . GLU A 1 632 ? 190.657 142.873 190.591 1.00 57.40  ? 632  GLU A OE2 1 
ATOM   4806  N  N   . GLY A 1 633 ? 191.251 147.736 188.614 1.00 51.11  ? 633  GLY A N   1 
ATOM   4807  C  CA  . GLY A 1 633 ? 190.527 147.756 187.357 1.00 51.11  ? 633  GLY A CA  1 
ATOM   4808  C  C   . GLY A 1 633 ? 189.060 148.120 187.466 1.00 51.11  ? 633  GLY A C   1 
ATOM   4809  O  O   . GLY A 1 633 ? 188.216 147.504 186.809 1.00 51.11  ? 633  GLY A O   1 
ATOM   4810  N  N   . HIS A 1 634 ? 188.739 149.115 188.290 1.00 49.53  ? 634  HIS A N   1 
ATOM   4811  C  CA  . HIS A 1 634 ? 187.361 149.541 188.504 1.00 49.53  ? 634  HIS A CA  1 
ATOM   4812  C  C   . HIS A 1 634 ? 187.242 151.024 188.191 1.00 49.53  ? 634  HIS A C   1 
ATOM   4813  O  O   . HIS A 1 634 ? 188.077 151.822 188.629 1.00 49.53  ? 634  HIS A O   1 
ATOM   4814  C  CB  . HIS A 1 634 ? 186.912 149.262 189.941 1.00 49.53  ? 634  HIS A CB  1 
ATOM   4815  C  CG  . HIS A 1 634 ? 186.767 147.807 190.258 1.00 49.53  ? 634  HIS A CG  1 
ATOM   4816  N  ND1 . HIS A 1 634 ? 185.964 146.962 189.523 1.00 49.53  ? 634  HIS A ND1 1 
ATOM   4817  C  CD2 . HIS A 1 634 ? 187.320 147.048 191.233 1.00 49.53  ? 634  HIS A CD2 1 
ATOM   4818  C  CE1 . HIS A 1 634 ? 186.030 145.744 190.031 1.00 49.53  ? 634  HIS A CE1 1 
ATOM   4819  N  NE2 . HIS A 1 634 ? 186.846 145.769 191.069 1.00 49.53  ? 634  HIS A NE2 1 
ATOM   4820  N  N   . VAL A 1 635 ? 186.212 151.389 187.435 1.00 43.03  ? 635  VAL A N   1 
ATOM   4821  C  CA  . VAL A 1 635 ? 185.911 152.792 187.172 1.00 43.03  ? 635  VAL A CA  1 
ATOM   4822  C  C   . VAL A 1 635 ? 184.957 153.282 188.254 1.00 43.03  ? 635  VAL A C   1 
ATOM   4823  O  O   . VAL A 1 635 ? 183.833 152.785 188.376 1.00 43.03  ? 635  VAL A O   1 
ATOM   4824  C  CB  . VAL A 1 635 ? 185.308 152.978 185.773 1.00 43.03  ? 635  VAL A CB  1 
ATOM   4825  C  CG1 . VAL A 1 635 ? 184.733 154.377 185.627 1.00 43.03  ? 635  VAL A CG1 1 
ATOM   4826  C  CG2 . VAL A 1 635 ? 186.358 152.712 184.705 1.00 43.03  ? 635  VAL A CG2 1 
ATOM   4827  N  N   . VAL A 1 636 ? 185.399 154.263 189.035 1.00 41.20  ? 636  VAL A N   1 
ATOM   4828  C  CA  . VAL A 1 636 ? 184.695 154.698 190.236 1.00 41.20  ? 636  VAL A CA  1 
ATOM   4829  C  C   . VAL A 1 636 ? 184.003 156.025 189.961 1.00 41.20  ? 636  VAL A C   1 
ATOM   4830  O  O   . VAL A 1 636 ? 184.609 156.954 189.409 1.00 41.20  ? 636  VAL A O   1 
ATOM   4831  C  CB  . VAL A 1 636 ? 185.652 154.811 191.435 1.00 41.20  ? 636  VAL A CB  1 
ATOM   4832  C  CG1 . VAL A 1 636 ? 184.988 155.554 192.579 1.00 41.20  ? 636  VAL A CG1 1 
ATOM   4833  C  CG2 . VAL A 1 636 ? 186.087 153.429 191.886 1.00 41.20  ? 636  VAL A CG2 1 
ATOM   4834  N  N   . GLY A 1 637 ? 182.730 156.105 190.337 1.00 38.68  ? 637  GLY A N   1 
ATOM   4835  C  CA  . GLY A 1 637 ? 181.999 157.351 190.288 1.00 38.68  ? 637  GLY A CA  1 
ATOM   4836  C  C   . GLY A 1 637 ? 181.597 157.821 191.668 1.00 38.68  ? 637  GLY A C   1 
ATOM   4837  O  O   . GLY A 1 637 ? 181.062 157.046 192.464 1.00 38.68  ? 637  GLY A O   1 
ATOM   4838  N  N   . PHE A 1 638 ? 181.852 159.090 191.964 1.00 37.19  ? 638  PHE A N   1 
ATOM   4839  C  CA  . PHE A 1 638 ? 181.528 159.669 193.260 1.00 37.19  ? 638  PHE A CA  1 
ATOM   4840  C  C   . PHE A 1 638 ? 180.452 160.726 193.078 1.00 37.19  ? 638  PHE A C   1 
ATOM   4841  O  O   . PHE A 1 638 ? 180.587 161.614 192.230 1.00 37.19  ? 638  PHE A O   1 
ATOM   4842  C  CB  . PHE A 1 638 ? 182.764 160.278 193.926 1.00 37.19  ? 638  PHE A CB  1 
ATOM   4843  C  CG  . PHE A 1 638 ? 182.509 160.795 195.314 1.00 37.19  ? 638  PHE A CG  1 
ATOM   4844  C  CD1 . PHE A 1 638 ? 182.605 159.953 196.408 1.00 37.19  ? 638  PHE A CD1 1 
ATOM   4845  C  CD2 . PHE A 1 638 ? 182.173 162.121 195.526 1.00 37.19  ? 638  PHE A CD2 1 
ATOM   4846  C  CE1 . PHE A 1 638 ? 182.372 160.423 197.684 1.00 37.19  ? 638  PHE A CE1 1 
ATOM   4847  C  CE2 . PHE A 1 638 ? 181.937 162.595 196.801 1.00 37.19  ? 638  PHE A CE2 1 
ATOM   4848  C  CZ  . PHE A 1 638 ? 182.038 161.745 197.881 1.00 37.19  ? 638  PHE A CZ  1 
ATOM   4849  N  N   . MET A 1 639 ? 179.389 160.628 193.870 1.00 35.40  ? 639  MET A N   1 
ATOM   4850  C  CA  . MET A 1 639 ? 178.286 161.579 193.836 1.00 35.40  ? 639  MET A CA  1 
ATOM   4851  C  C   . MET A 1 639 ? 178.240 162.328 195.159 1.00 35.40  ? 639  MET A C   1 
ATOM   4852  O  O   . MET A 1 639 ? 178.080 161.713 196.219 1.00 35.40  ? 639  MET A O   1 
ATOM   4853  C  CB  . MET A 1 639 ? 176.959 160.871 193.569 1.00 35.40  ? 639  MET A CB  1 
ATOM   4854  C  CG  . MET A 1 639 ? 175.770 161.808 193.464 1.00 35.40  ? 639  MET A CG  1 
ATOM   4855  S  SD  . MET A 1 639 ? 174.205 160.930 193.299 1.00 35.40  ? 639  MET A SD  1 
ATOM   4856  C  CE  . MET A 1 639 ? 173.093 162.292 192.963 1.00 35.40  ? 639  MET A CE  1 
ATOM   4857  N  N   . GLY A 1 640 ? 178.375 163.648 195.095 1.00 36.33  ? 640  GLY A N   1 
ATOM   4858  C  CA  . GLY A 1 640 ? 178.368 164.465 196.292 1.00 36.33  ? 640  GLY A CA  1 
ATOM   4859  C  C   . GLY A 1 640 ? 178.083 165.907 195.951 1.00 36.33  ? 640  GLY A C   1 
ATOM   4860  O  O   . GLY A 1 640 ? 178.310 166.351 194.821 1.00 36.33  ? 640  GLY A O   1 
ATOM   4861  N  N   . ASP A 1 641 ? 177.574 166.643 196.936 1.00 42.05  ? 641  ASP A N   1 
ATOM   4862  C  CA  . ASP A 1 641 ? 177.222 168.047 196.757 1.00 42.05  ? 641  ASP A CA  1 
ATOM   4863  C  C   . ASP A 1 641 ? 177.606 168.858 197.987 1.00 42.05  ? 641  ASP A C   1 
ATOM   4864  O  O   . ASP A 1 641 ? 176.887 169.776 198.397 1.00 42.05  ? 641  ASP A O   1 
ATOM   4865  C  CB  . ASP A 1 641 ? 175.734 168.204 196.446 1.00 42.05  ? 641  ASP A CB  1 
ATOM   4866  C  CG  . ASP A 1 641 ? 174.846 167.553 197.490 1.00 42.05  ? 641  ASP A CG  1 
ATOM   4867  O  OD1 . ASP A 1 641 ? 175.379 166.876 198.394 1.00 42.05  ? 641  ASP A OD1 1 
ATOM   4868  O  OD2 . ASP A 1 641 ? 173.611 167.715 197.404 1.00 42.05  ? 641  ASP A OD2 1 
ATOM   4869  N  N   . GLY A 1 642 ? 178.745 168.528 198.597 1.00 42.78  ? 642  GLY A N   1 
ATOM   4870  C  CA  . GLY A 1 642 ? 179.225 169.216 199.773 1.00 42.78  ? 642  GLY A CA  1 
ATOM   4871  C  C   . GLY A 1 642 ? 180.377 170.159 199.459 1.00 42.78  ? 642  GLY A C   1 
ATOM   4872  O  O   . GLY A 1 642 ? 180.918 170.189 198.355 1.00 42.78  ? 642  GLY A O   1 
ATOM   4873  N  N   . ILE A 1 643 ? 180.745 170.945 200.474 1.00 42.03  ? 643  ILE A N   1 
ATOM   4874  C  CA  . ILE A 1 643 ? 181.844 171.894 200.322 1.00 42.03  ? 643  ILE A CA  1 
ATOM   4875  C  C   . ILE A 1 643 ? 183.159 171.161 200.091 1.00 42.03  ? 643  ILE A C   1 
ATOM   4876  O  O   . ILE A 1 643 ? 183.958 171.542 199.228 1.00 42.03  ? 643  ILE A O   1 
ATOM   4877  C  CB  . ILE A 1 643 ? 181.925 172.821 201.550 1.00 42.03  ? 643  ILE A CB  1 
ATOM   4878  C  CG1 . ILE A 1 643 ? 180.715 173.753 201.602 1.00 42.03  ? 643  ILE A CG1 1 
ATOM   4879  C  CG2 . ILE A 1 643 ? 183.212 173.628 201.528 1.00 42.03  ? 643  ILE A CG2 1 
ATOM   4880  C  CD1 . ILE A 1 643 ? 180.760 174.739 202.748 1.00 42.03  ? 643  ILE A CD1 1 
ATOM   4881  N  N   . ASN A 1 644 ? 183.402 170.096 200.850 1.00 44.97  ? 644  ASN A N   1 
ATOM   4882  C  CA  . ASN A 1 644 ? 184.666 169.376 200.806 1.00 44.97  ? 644  ASN A CA  1 
ATOM   4883  C  C   . ASN A 1 644 ? 184.630 168.168 199.879 1.00 44.97  ? 644  ASN A C   1 
ATOM   4884  O  O   . ASN A 1 644 ? 185.504 167.301 199.976 1.00 44.97  ? 644  ASN A O   1 
ATOM   4885  C  CB  . ASN A 1 644 ? 185.068 168.938 202.214 1.00 44.97  ? 644  ASN A CB  1 
ATOM   4886  C  CG  . ASN A 1 644 ? 184.929 170.052 203.229 1.00 44.97  ? 644  ASN A CG  1 
ATOM   4887  O  OD1 . ASN A 1 644 ? 183.949 170.113 203.970 1.00 44.97  ? 644  ASN A OD1 1 
ATOM   4888  N  ND2 . ASN A 1 644 ? 185.914 170.941 203.271 1.00 44.97  ? 644  ASN A ND2 1 
ATOM   4889  N  N   . ASP A 1 645 ? 183.645 168.086 198.989 1.00 42.69  ? 645  ASP A N   1 
ATOM   4890  C  CA  . ASP A 1 645 ? 183.554 166.977 198.051 1.00 42.69  ? 645  ASP A CA  1 
ATOM   4891  C  C   . ASP A 1 645 ? 184.384 167.192 196.793 1.00 42.69  ? 645  ASP A C   1 
ATOM   4892  O  O   . ASP A 1 645 ? 184.436 166.294 195.946 1.00 42.69  ? 645  ASP A O   1 
ATOM   4893  C  CB  . ASP A 1 645 ? 182.094 166.727 197.664 1.00 42.69  ? 645  ASP A CB  1 
ATOM   4894  C  CG  . ASP A 1 645 ? 181.282 166.146 198.802 1.00 42.69  ? 645  ASP A CG  1 
ATOM   4895  O  OD1 . ASP A 1 645 ? 181.882 165.526 199.705 1.00 42.69  ? 645  ASP A OD1 1 
ATOM   4896  O  OD2 . ASP A 1 645 ? 180.043 166.297 198.788 1.00 42.69  ? 645  ASP A OD2 1 
ATOM   4897  N  N   . ALA A 1 646 ? 185.028 168.349 196.647 1.00 37.56  ? 646  ALA A N   1 
ATOM   4898  C  CA  . ALA A 1 646 ? 185.843 168.591 195.458 1.00 37.56  ? 646  ALA A CA  1 
ATOM   4899  C  C   . ALA A 1 646 ? 187.007 167.616 195.329 1.00 37.56  ? 646  ALA A C   1 
ATOM   4900  O  O   . ALA A 1 646 ? 187.201 167.070 194.229 1.00 37.56  ? 646  ALA A O   1 
ATOM   4901  C  CB  . ALA A 1 646 ? 186.321 170.047 195.447 1.00 37.56  ? 646  ALA A CB  1 
ATOM   4902  N  N   . PRO A 1 647 ? 187.820 167.360 196.366 1.00 41.41  ? 647  PRO A N   1 
ATOM   4903  C  CA  . PRO A 1 647 ? 188.855 166.323 196.214 1.00 41.41  ? 647  PRO A CA  1 
ATOM   4904  C  C   . PRO A 1 647 ? 188.287 164.955 195.888 1.00 41.41  ? 647  PRO A C   1 
ATOM   4905  O  O   . PRO A 1 647 ? 188.871 164.223 195.081 1.00 41.41  ? 647  PRO A O   1 
ATOM   4906  C  CB  . PRO A 1 647 ? 189.564 166.334 197.576 1.00 41.41  ? 647  PRO A CB  1 
ATOM   4907  C  CG  . PRO A 1 647 ? 189.299 167.681 198.127 1.00 41.41  ? 647  PRO A CG  1 
ATOM   4908  C  CD  . PRO A 1 647 ? 187.911 168.016 197.683 1.00 41.41  ? 647  PRO A CD  1 
ATOM   4909  N  N   . ALA A 1 648 ? 187.151 164.591 196.486 1.00 37.17  ? 648  ALA A N   1 
ATOM   4910  C  CA  . ALA A 1 648 ? 186.553 163.291 196.202 1.00 37.17  ? 648  ALA A CA  1 
ATOM   4911  C  C   . ALA A 1 648 ? 186.025 163.224 194.776 1.00 37.17  ? 648  ALA A C   1 
ATOM   4912  O  O   . ALA A 1 648 ? 186.217 162.217 194.085 1.00 37.17  ? 648  ALA A O   1 
ATOM   4913  C  CB  . ALA A 1 648 ? 185.437 162.995 197.202 1.00 37.17  ? 648  ALA A CB  1 
ATOM   4914  N  N   . LEU A 1 649 ? 185.352 164.282 194.321 1.00 36.34  ? 649  LEU A N   1 
ATOM   4915  C  CA  . LEU A 1 649 ? 184.828 164.295 192.960 1.00 36.34  ? 649  LEU A CA  1 
ATOM   4916  C  C   . LEU A 1 649 ? 185.952 164.261 191.933 1.00 36.34  ? 649  LEU A C   1 
ATOM   4917  O  O   . LEU A 1 649 ? 185.850 163.565 190.917 1.00 36.34  ? 649  LEU A O   1 
ATOM   4918  C  CB  . LEU A 1 649 ? 183.945 165.524 192.749 1.00 36.34  ? 649  LEU A CB  1 
ATOM   4919  C  CG  . LEU A 1 649 ? 182.574 165.515 193.427 1.00 36.34  ? 649  LEU A CG  1 
ATOM   4920  C  CD1 . LEU A 1 649 ? 182.076 166.933 193.645 1.00 36.34  ? 649  LEU A CD1 1 
ATOM   4921  C  CD2 . LEU A 1 649 ? 181.577 164.718 192.610 1.00 36.34  ? 649  LEU A CD2 1 
ATOM   4922  N  N   . ARG A 1 650 ? 187.032 165.007 192.176 1.00 40.55  ? 650  ARG A N   1 
ATOM   4923  C  CA  . ARG A 1 650 ? 188.133 165.038 191.219 1.00 40.55  ? 650  ARG A CA  1 
ATOM   4924  C  C   . ARG A 1 650 ? 188.939 163.745 191.235 1.00 40.55  ? 650  ARG A C   1 
ATOM   4925  O  O   . ARG A 1 650 ? 189.382 163.283 190.177 1.00 40.55  ? 650  ARG A O   1 
ATOM   4926  C  CB  . ARG A 1 650 ? 189.038 166.235 191.503 1.00 40.55  ? 650  ARG A CB  1 
ATOM   4927  C  CG  . ARG A 1 650 ? 190.212 166.381 190.548 1.00 40.55  ? 650  ARG A CG  1 
ATOM   4928  C  CD  . ARG A 1 650 ? 189.757 166.698 189.133 1.00 40.55  ? 650  ARG A CD  1 
ATOM   4929  N  NE  . ARG A 1 650 ? 188.722 167.724 189.109 1.00 40.55  ? 650  ARG A NE  1 
ATOM   4930  C  CZ  . ARG A 1 650 ? 188.351 168.390 188.025 1.00 40.55  ? 650  ARG A CZ  1 
ATOM   4931  N  NH1 . ARG A 1 650 ? 188.940 168.193 186.859 1.00 40.55  ? 650  ARG A NH1 1 
ATOM   4932  N  NH2 . ARG A 1 650 ? 187.373 169.286 188.116 1.00 40.55  ? 650  ARG A NH2 1 
ATOM   4933  N  N   . ALA A 1 651 ? 189.137 163.147 192.411 1.00 42.15  ? 651  ALA A N   1 
ATOM   4934  C  CA  . ALA A 1 651 ? 189.917 161.921 192.508 1.00 42.15  ? 651  ALA A CA  1 
ATOM   4935  C  C   . ALA A 1 651 ? 189.196 160.717 191.920 1.00 42.15  ? 651  ALA A C   1 
ATOM   4936  O  O   . ALA A 1 651 ? 189.856 159.755 191.512 1.00 42.15  ? 651  ALA A O   1 
ATOM   4937  C  CB  . ALA A 1 651 ? 190.279 161.642 193.968 1.00 42.15  ? 651  ALA A CB  1 
ATOM   4938  N  N   . ALA A 1 652 ? 187.869 160.745 191.869 1.00 40.06  ? 652  ALA A N   1 
ATOM   4939  C  CA  . ALA A 1 652 ? 187.121 159.648 191.280 1.00 40.06  ? 652  ALA A CA  1 
ATOM   4940  C  C   . ALA A 1 652 ? 187.289 159.640 189.765 1.00 40.06  ? 652  ALA A C   1 
ATOM   4941  O  O   . ALA A 1 652 ? 187.612 160.655 189.142 1.00 40.06  ? 652  ALA A O   1 
ATOM   4942  C  CB  . ALA A 1 652 ? 185.640 159.753 191.640 1.00 40.06  ? 652  ALA A CB  1 
ATOM   4943  N  N   . ASP A 1 653 ? 187.072 158.464 189.171 1.00 42.47  ? 653  ASP A N   1 
ATOM   4944  C  CA  . ASP A 1 653 ? 187.104 158.371 187.716 1.00 42.47  ? 653  ASP A CA  1 
ATOM   4945  C  C   . ASP A 1 653 ? 186.035 159.248 187.084 1.00 42.47  ? 653  ASP A C   1 
ATOM   4946  O  O   . ASP A 1 653 ? 186.265 159.834 186.020 1.00 42.47  ? 653  ASP A O   1 
ATOM   4947  C  CB  . ASP A 1 653 ? 186.944 156.919 187.270 1.00 42.47  ? 653  ASP A CB  1 
ATOM   4948  C  CG  . ASP A 1 653 ? 188.269 156.191 187.182 1.00 42.47  ? 653  ASP A CG  1 
ATOM   4949  O  OD1 . ASP A 1 653 ? 189.283 156.844 186.857 1.00 42.47  ? 653  ASP A OD1 1 
ATOM   4950  O  OD2 . ASP A 1 653 ? 188.299 154.970 187.437 1.00 42.47  ? 653  ASP A OD2 1 
ATOM   4951  N  N   . ILE A 1 654 ? 184.867 159.355 187.713 1.00 37.44  ? 654  ILE A N   1 
ATOM   4952  C  CA  . ILE A 1 654 ? 183.858 160.320 187.291 1.00 37.44  ? 654  ILE A CA  1 
ATOM   4953  C  C   . ILE A 1 654 ? 183.192 160.921 188.523 1.00 37.44  ? 654  ILE A C   1 
ATOM   4954  O  O   . ILE A 1 654 ? 182.994 160.239 189.534 1.00 37.44  ? 654  ILE A O   1 
ATOM   4955  C  CB  . ILE A 1 654 ? 182.822 159.691 186.336 1.00 37.44  ? 654  ILE A CB  1 
ATOM   4956  C  CG1 . ILE A 1 654 ? 181.856 160.759 185.827 1.00 37.44  ? 654  ILE A CG1 1 
ATOM   4957  C  CG2 . ILE A 1 654 ? 182.079 158.555 187.004 1.00 37.44  ? 654  ILE A CG2 1 
ATOM   4958  C  CD1 . ILE A 1 654 ? 181.032 160.319 184.664 1.00 37.44  ? 654  ILE A CD1 1 
ATOM   4959  N  N   . GLY A 1 655 ? 182.881 162.212 188.443 1.00 34.54  ? 655  GLY A N   1 
ATOM   4960  C  CA  . GLY A 1 655 ? 182.218 162.930 189.516 1.00 34.54  ? 655  GLY A CA  1 
ATOM   4961  C  C   . GLY A 1 655 ? 180.855 163.429 189.065 1.00 34.54  ? 655  GLY A C   1 
ATOM   4962  O  O   . GLY A 1 655 ? 180.728 164.056 188.010 1.00 34.54  ? 655  GLY A O   1 
ATOM   4963  N  N   . ILE A 1 656 ? 179.845 163.138 189.880 1.00 31.80  ? 656  ILE A N   1 
ATOM   4964  C  CA  . ILE A 1 656 ? 178.462 163.504 189.602 1.00 31.80  ? 656  ILE A CA  1 
ATOM   4965  C  C   . ILE A 1 656 ? 177.975 164.406 190.725 1.00 31.80  ? 656  ILE A C   1 
ATOM   4966  O  O   . ILE A 1 656 ? 178.158 164.089 191.906 1.00 31.80  ? 656  ILE A O   1 
ATOM   4967  C  CB  . ILE A 1 656 ? 177.566 162.260 189.469 1.00 31.80  ? 656  ILE A CB  1 
ATOM   4968  C  CG1 . ILE A 1 656 ? 178.287 161.171 188.674 1.00 31.80  ? 656  ILE A CG1 1 
ATOM   4969  C  CG2 . ILE A 1 656 ? 176.255 162.623 188.801 1.00 31.80  ? 656  ILE A CG2 1 
ATOM   4970  C  CD1 . ILE A 1 656 ? 177.667 159.804 188.808 1.00 31.80  ? 656  ILE A CD1 1 
ATOM   4971  N  N   . SER A 1 657 ? 177.365 165.531 190.360 1.00 33.07  ? 657  SER A N   1 
ATOM   4972  C  CA  . SER A 1 657 ? 176.853 166.483 191.334 1.00 33.07  ? 657  SER A CA  1 
ATOM   4973  C  C   . SER A 1 657 ? 175.426 166.855 190.962 1.00 33.07  ? 657  SER A C   1 
ATOM   4974  O  O   . SER A 1 657 ? 174.854 166.332 190.002 1.00 33.07  ? 657  SER A O   1 
ATOM   4975  C  CB  . SER A 1 657 ? 177.739 167.729 191.414 1.00 33.07  ? 657  SER A CB  1 
ATOM   4976  O  OG  . SER A 1 657 ? 177.199 168.678 192.316 1.00 33.07  ? 657  SER A OG  1 
ATOM   4977  N  N   . VAL A 1 658 ? 174.853 167.776 191.729 1.00 36.12  ? 658  VAL A N   1 
ATOM   4978  C  CA  . VAL A 1 658 ? 173.481 168.225 191.540 1.00 36.12  ? 658  VAL A CA  1 
ATOM   4979  C  C   . VAL A 1 658 ? 173.508 169.697 191.158 1.00 36.12  ? 658  VAL A C   1 
ATOM   4980  O  O   . VAL A 1 658 ? 174.440 170.429 191.506 1.00 36.12  ? 658  VAL A O   1 
ATOM   4981  C  CB  . VAL A 1 658 ? 172.635 167.994 192.812 1.00 36.12  ? 658  VAL A CB  1 
ATOM   4982  C  CG1 . VAL A 1 658 ? 171.153 168.215 192.534 1.00 36.12  ? 658  VAL A CG1 1 
ATOM   4983  C  CG2 . VAL A 1 658 ? 172.880 166.600 193.361 1.00 36.12  ? 658  VAL A CG2 1 
ATOM   4984  N  N   . ASP A 1 659 ? 172.478 170.128 190.426 1.00 43.76  ? 659  ASP A N   1 
ATOM   4985  C  CA  . ASP A 1 659 ? 172.402 171.520 189.994 1.00 43.76  ? 659  ASP A CA  1 
ATOM   4986  C  C   . ASP A 1 659 ? 172.363 172.465 191.188 1.00 43.76  ? 659  ASP A C   1 
ATOM   4987  O  O   . ASP A 1 659 ? 173.038 173.500 191.200 1.00 43.76  ? 659  ASP A O   1 
ATOM   4988  C  CB  . ASP A 1 659 ? 171.175 171.724 189.105 1.00 43.76  ? 659  ASP A CB  1 
ATOM   4989  C  CG  . ASP A 1 659 ? 170.950 173.179 188.749 1.00 43.76  ? 659  ASP A CG  1 
ATOM   4990  O  OD1 . ASP A 1 659 ? 171.858 173.794 188.151 1.00 43.76  ? 659  ASP A OD1 1 
ATOM   4991  O  OD2 . ASP A 1 659 ? 169.865 173.708 189.068 1.00 43.76  ? 659  ASP A OD2 1 
ATOM   4992  N  N   . GLY A 1 660 ? 171.574 172.125 192.204 1.00 45.11  ? 660  GLY A N   1 
ATOM   4993  C  CA  . GLY A 1 660 ? 171.544 172.914 193.418 1.00 45.11  ? 660  GLY A CA  1 
ATOM   4994  C  C   . GLY A 1 660 ? 172.563 172.440 194.432 1.00 45.11  ? 660  GLY A C   1 
ATOM   4995  O  O   . GLY A 1 660 ? 172.310 171.489 195.179 1.00 45.11  ? 660  GLY A O   1 
ATOM   4996  N  N   . ALA A 1 661 ? 173.717 173.101 194.472 1.00 45.52  ? 661  ALA A N   1 
ATOM   4997  C  CA  . ALA A 1 661 ? 174.804 172.709 195.359 1.00 45.52  ? 661  ALA A CA  1 
ATOM   4998  C  C   . ALA A 1 661 ? 175.804 173.852 195.433 1.00 45.52  ? 661  ALA A C   1 
ATOM   4999  O  O   . ALA A 1 661 ? 175.658 174.877 194.763 1.00 45.52  ? 661  ALA A O   1 
ATOM   5000  C  CB  . ALA A 1 661 ? 175.483 171.422 194.881 1.00 45.52  ? 661  ALA A CB  1 
ATOM   5001  N  N   . VAL A 1 662 ? 176.828 173.661 196.267 1.00 45.35  ? 662  VAL A N   1 
ATOM   5002  C  CA  . VAL A 1 662 ? 177.899 174.642 196.347 1.00 45.35  ? 662  VAL A CA  1 
ATOM   5003  C  C   . VAL A 1 662 ? 178.672 174.653 195.033 1.00 45.35  ? 662  VAL A C   1 
ATOM   5004  O  O   . VAL A 1 662 ? 178.693 173.666 194.286 1.00 45.35  ? 662  VAL A O   1 
ATOM   5005  C  CB  . VAL A 1 662 ? 178.827 174.353 197.537 1.00 45.35  ? 662  VAL A CB  1 
ATOM   5006  C  CG1 . VAL A 1 662 ? 178.059 174.470 198.839 1.00 45.35  ? 662  VAL A CG1 1 
ATOM   5007  C  CG2 . VAL A 1 662 ? 179.435 172.971 197.408 1.00 45.35  ? 662  VAL A CG2 1 
ATOM   5008  N  N   . ASP A 1 663 ? 179.307 175.790 194.742 1.00 50.25  ? 663  ASP A N   1 
ATOM   5009  C  CA  . ASP A 1 663 ? 179.954 175.961 193.445 1.00 50.25  ? 663  ASP A CA  1 
ATOM   5010  C  C   . ASP A 1 663 ? 181.115 174.990 193.261 1.00 50.25  ? 663  ASP A C   1 
ATOM   5011  O  O   . ASP A 1 663 ? 181.285 174.417 192.178 1.00 50.25  ? 663  ASP A O   1 
ATOM   5012  C  CB  . ASP A 1 663 ? 180.427 177.404 193.286 1.00 50.25  ? 663  ASP A CB  1 
ATOM   5013  C  CG  . ASP A 1 663 ? 179.278 178.389 193.228 1.00 50.25  ? 663  ASP A CG  1 
ATOM   5014  O  OD1 . ASP A 1 663 ? 178.115 177.960 193.378 1.00 50.25  ? 663  ASP A OD1 1 
ATOM   5015  O  OD2 . ASP A 1 663 ? 179.538 179.595 193.031 1.00 50.25  ? 663  ASP A OD2 1 
ATOM   5016  N  N   . ILE A 1 664 ? 181.921 174.784 194.306 1.00 41.05  ? 664  ILE A N   1 
ATOM   5017  C  CA  . ILE A 1 664 ? 183.083 173.908 194.192 1.00 41.05  ? 664  ILE A CA  1 
ATOM   5018  C  C   . ILE A 1 664 ? 182.709 172.453 193.962 1.00 41.05  ? 664  ILE A C   1 
ATOM   5019  O  O   . ILE A 1 664 ? 183.536 171.685 193.458 1.00 41.05  ? 664  ILE A O   1 
ATOM   5020  C  CB  . ILE A 1 664 ? 183.981 174.029 195.441 1.00 41.05  ? 664  ILE A CB  1 
ATOM   5021  C  CG1 . ILE A 1 664 ? 185.416 173.606 195.118 1.00 41.05  ? 664  ILE A CG1 1 
ATOM   5022  C  CG2 . ILE A 1 664 ? 183.426 173.207 196.587 1.00 41.05  ? 664  ILE A CG2 1 
ATOM   5023  C  CD1 . ILE A 1 664 ? 186.114 174.511 194.131 1.00 41.05  ? 664  ILE A CD1 1 
ATOM   5024  N  N   . ALA A 1 665 ? 181.490 172.048 194.311 1.00 37.08  ? 665  ALA A N   1 
ATOM   5025  C  CA  . ALA A 1 665 ? 181.015 170.706 194.011 1.00 37.08  ? 665  ALA A CA  1 
ATOM   5026  C  C   . ALA A 1 665 ? 180.452 170.593 192.604 1.00 37.08  ? 665  ALA A C   1 
ATOM   5027  O  O   . ALA A 1 665 ? 180.214 169.478 192.134 1.00 37.08  ? 665  ALA A O   1 
ATOM   5028  C  CB  . ALA A 1 665 ? 179.957 170.273 195.029 1.00 37.08  ? 665  ALA A CB  1 
ATOM   5029  N  N   . ARG A 1 666 ? 180.245 171.717 191.920 1.00 41.36  ? 666  ARG A N   1 
ATOM   5030  C  CA  . ARG A 1 666 ? 179.804 171.731 190.532 1.00 41.36  ? 666  ARG A CA  1 
ATOM   5031  C  C   . ARG A 1 666 ? 180.964 171.940 189.569 1.00 41.36  ? 666  ARG A C   1 
ATOM   5032  O  O   . ARG A 1 666 ? 180.984 171.357 188.482 1.00 41.36  ? 666  ARG A O   1 
ATOM   5033  C  CB  . ARG A 1 666 ? 178.750 172.824 190.327 1.00 41.36  ? 666  ARG A CB  1 
ATOM   5034  C  CG  . ARG A 1 666 ? 177.444 172.567 191.055 1.00 41.36  ? 666  ARG A CG  1 
ATOM   5035  C  CD  . ARG A 1 666 ? 176.584 173.817 191.090 1.00 41.36  ? 666  ARG A CD  1 
ATOM   5036  N  NE  . ARG A 1 666 ? 176.726 174.611 189.876 1.00 41.36  ? 666  ARG A NE  1 
ATOM   5037  C  CZ  . ARG A 1 666 ? 175.734 174.884 189.040 1.00 41.36  ? 666  ARG A CZ  1 
ATOM   5038  N  NH1 . ARG A 1 666 ? 174.506 174.443 189.258 1.00 41.36  ? 666  ARG A NH1 1 
ATOM   5039  N  NH2 . ARG A 1 666 ? 175.980 175.619 187.960 1.00 41.36  ? 666  ARG A NH2 1 
ATOM   5040  N  N   . GLU A 1 667 ? 181.935 172.771 189.952 1.00 40.60  ? 667  GLU A N   1 
ATOM   5041  C  CA  . GLU A 1 667 ? 183.123 172.955 189.128 1.00 40.60  ? 667  GLU A CA  1 
ATOM   5042  C  C   . GLU A 1 667 ? 183.935 171.670 189.044 1.00 40.60  ? 667  GLU A C   1 
ATOM   5043  O  O   . GLU A 1 667 ? 184.468 171.329 187.982 1.00 40.60  ? 667  GLU A O   1 
ATOM   5044  C  CB  . GLU A 1 667 ? 183.978 174.090 189.691 1.00 40.60  ? 667  GLU A CB  1 
ATOM   5045  C  CG  . GLU A 1 667 ? 184.940 174.697 188.687 1.00 40.60  ? 667  GLU A CG  1 
ATOM   5046  C  CD  . GLU A 1 667 ? 184.275 175.732 187.803 1.00 40.60  ? 667  GLU A CD  1 
ATOM   5047  O  OE1 . GLU A 1 667 ? 183.095 176.057 188.051 1.00 40.60  ? 667  GLU A OE1 1 
ATOM   5048  O  OE2 . GLU A 1 667 ? 184.931 176.221 186.859 1.00 40.60  ? 667  GLU A OE2 1 
ATOM   5049  N  N   . ALA A 1 668 ? 184.041 170.944 190.158 1.00 36.03  ? 668  ALA A N   1 
ATOM   5050  C  CA  . ALA A 1 668 ? 184.834 169.723 190.195 1.00 36.03  ? 668  ALA A CA  1 
ATOM   5051  C  C   . ALA A 1 668 ? 184.120 168.529 189.579 1.00 36.03  ? 668  ALA A C   1 
ATOM   5052  O  O   . ALA A 1 668 ? 184.772 167.522 189.285 1.00 36.03  ? 668  ALA A O   1 
ATOM   5053  C  CB  . ALA A 1 668 ? 185.223 169.393 191.637 1.00 36.03  ? 668  ALA A CB  1 
ATOM   5054  N  N   . ALA A 1 669 ? 182.811 168.613 189.378 1.00 33.64  ? 669  ALA A N   1 
ATOM   5055  C  CA  . ALA A 1 669 ? 182.063 167.481 188.858 1.00 33.64  ? 669  ALA A CA  1 
ATOM   5056  C  C   . ALA A 1 669 ? 182.180 167.398 187.340 1.00 33.64  ? 669  ALA A C   1 
ATOM   5057  O  O   . ALA A 1 669 ? 182.493 168.375 186.655 1.00 33.64  ? 669  ALA A O   1 
ATOM   5058  C  CB  . ALA A 1 669 ? 180.593 167.578 189.260 1.00 33.64  ? 669  ALA A CB  1 
ATOM   5059  N  N   . ASP A 1 670 ? 181.922 166.200 186.818 1.00 34.36  ? 670  ASP A N   1 
ATOM   5060  C  CA  . ASP A 1 670 ? 181.877 165.970 185.381 1.00 34.36  ? 670  ASP A CA  1 
ATOM   5061  C  C   . ASP A 1 670 ? 180.461 165.807 184.850 1.00 34.36  ? 670  ASP A C   1 
ATOM   5062  O  O   . ASP A 1 670 ? 180.221 166.065 183.667 1.00 34.36  ? 670  ASP A O   1 
ATOM   5063  C  CB  . ASP A 1 670 ? 182.693 164.726 185.017 1.00 34.36  ? 670  ASP A CB  1 
ATOM   5064  C  CG  . ASP A 1 670 ? 184.177 164.922 185.233 1.00 34.36  ? 670  ASP A CG  1 
ATOM   5065  O  OD1 . ASP A 1 670 ? 184.647 166.074 185.122 1.00 34.36  ? 670  ASP A OD1 1 
ATOM   5066  O  OD2 . ASP A 1 670 ? 184.875 163.926 185.515 1.00 34.36  ? 670  ASP A OD2 1 
ATOM   5067  N  N   . ILE A 1 671 ? 179.524 165.385 185.695 1.00 29.32  ? 671  ILE A N   1 
ATOM   5068  C  CA  . ILE A 1 671 ? 178.121 165.238 185.330 1.00 29.32  ? 671  ILE A CA  1 
ATOM   5069  C  C   . ILE A 1 671 ? 177.291 166.034 186.326 1.00 29.32  ? 671  ILE A C   1 
ATOM   5070  O  O   . ILE A 1 671 ? 177.599 166.048 187.523 1.00 29.32  ? 671  ILE A O   1 
ATOM   5071  C  CB  . ILE A 1 671 ? 177.692 163.757 185.319 1.00 29.32  ? 671  ILE A CB  1 
ATOM   5072  C  CG1 . ILE A 1 671 ? 178.575 162.953 184.367 1.00 29.32  ? 671  ILE A CG1 1 
ATOM   5073  C  CG2 . ILE A 1 671 ? 176.237 163.620 184.919 1.00 29.32  ? 671  ILE A CG2 1 
ATOM   5074  C  CD1 . ILE A 1 671 ? 178.421 163.345 182.925 1.00 29.32  ? 671  ILE A CD1 1 
ATOM   5075  N  N   . ILE A 1 672 ? 176.253 166.709 185.838 1.00 30.10  ? 672  ILE A N   1 
ATOM   5076  C  CA  . ILE A 1 672 ? 175.369 167.500 186.688 1.00 30.10  ? 672  ILE A CA  1 
ATOM   5077  C  C   . ILE A 1 672 ? 173.949 166.994 186.486 1.00 30.10  ? 672  ILE A C   1 
ATOM   5078  O  O   . ILE A 1 672 ? 173.397 167.096 185.384 1.00 30.10  ? 672  ILE A O   1 
ATOM   5079  C  CB  . ILE A 1 672 ? 175.467 169.000 186.383 1.00 30.10  ? 672  ILE A CB  1 
ATOM   5080  C  CG1 . ILE A 1 672 ? 176.899 169.494 186.590 1.00 30.10  ? 672  ILE A CG1 1 
ATOM   5081  C  CG2 . ILE A 1 672 ? 174.502 169.783 187.256 1.00 30.10  ? 672  ILE A CG2 1 
ATOM   5082  C  CD1 . ILE A 1 672 ? 177.343 169.497 188.034 1.00 30.10  ? 672  ILE A CD1 1 
ATOM   5083  N  N   . LEU A 1 673 ? 173.351 166.454 187.542 1.00 31.09  ? 673  LEU A N   1 
ATOM   5084  C  CA  . LEU A 1 673 ? 171.957 166.044 187.484 1.00 31.09  ? 673  LEU A CA  1 
ATOM   5085  C  C   . LEU A 1 673 ? 171.064 167.204 187.899 1.00 31.09  ? 673  LEU A C   1 
ATOM   5086  O  O   . LEU A 1 673 ? 171.307 167.858 188.916 1.00 31.09  ? 673  LEU A O   1 
ATOM   5087  C  CB  . LEU A 1 673 ? 171.713 164.838 188.390 1.00 31.09  ? 673  LEU A CB  1 
ATOM   5088  C  CG  . LEU A 1 673 ? 172.776 163.740 188.365 1.00 31.09  ? 673  LEU A CG  1 
ATOM   5089  C  CD1 . LEU A 1 673 ? 172.394 162.604 189.297 1.00 31.09  ? 673  LEU A CD1 1 
ATOM   5090  C  CD2 . LEU A 1 673 ? 172.985 163.225 186.953 1.00 31.09  ? 673  LEU A CD2 1 
ATOM   5091  N  N   . LEU A 1 674 ? 170.029 167.463 187.098 1.00 33.95  ? 674  LEU A N   1 
ATOM   5092  C  CA  . LEU A 1 674 ? 169.127 168.566 187.408 1.00 33.95  ? 674  LEU A CA  1 
ATOM   5093  C  C   . LEU A 1 674 ? 168.365 168.320 188.704 1.00 33.95  ? 674  LEU A C   1 
ATOM   5094  O  O   . LEU A 1 674 ? 167.971 169.276 189.380 1.00 33.95  ? 674  LEU A O   1 
ATOM   5095  C  CB  . LEU A 1 674 ? 168.160 168.797 186.248 1.00 33.95  ? 674  LEU A CB  1 
ATOM   5096  C  CG  . LEU A 1 674 ? 168.816 169.251 184.942 1.00 33.95  ? 674  LEU A CG  1 
ATOM   5097  C  CD1 . LEU A 1 674 ? 167.772 169.516 183.869 1.00 33.95  ? 674  LEU A CD1 1 
ATOM   5098  C  CD2 . LEU A 1 674 ? 169.672 170.485 185.176 1.00 33.95  ? 674  LEU A CD2 1 
ATOM   5099  N  N   . GLU A 1 675 ? 168.149 167.058 189.065 1.00 37.46  ? 675  GLU A N   1 
ATOM   5100  C  CA  . GLU A 1 675 ? 167.578 166.700 190.354 1.00 37.46  ? 675  GLU A CA  1 
ATOM   5101  C  C   . GLU A 1 675 ? 168.378 165.553 190.953 1.00 37.46  ? 675  GLU A C   1 
ATOM   5102  O  O   . GLU A 1 675 ? 168.939 164.723 190.233 1.00 37.46  ? 675  GLU A O   1 
ATOM   5103  C  CB  . GLU A 1 675 ? 166.097 166.313 190.239 1.00 37.46  ? 675  GLU A CB  1 
ATOM   5104  C  CG  . GLU A 1 675 ? 165.839 165.007 189.514 1.00 37.46  ? 675  GLU A CG  1 
ATOM   5105  C  CD  . GLU A 1 675 ? 164.366 164.650 189.476 1.00 37.46  ? 675  GLU A CD  1 
ATOM   5106  O  OE1 . GLU A 1 675 ? 163.551 165.441 189.994 1.00 37.46  ? 675  GLU A OE1 1 
ATOM   5107  O  OE2 . GLU A 1 675 ? 164.024 163.581 188.929 1.00 37.46  ? 675  GLU A OE2 1 
ATOM   5108  N  N   . LYS A 1 676 ? 168.432 165.519 192.281 1.00 36.00  ? 676  LYS A N   1 
ATOM   5109  C  CA  . LYS A 1 676 ? 169.227 164.529 193.005 1.00 36.00  ? 676  LYS A CA  1 
ATOM   5110  C  C   . LYS A 1 676 ? 168.392 163.268 193.182 1.00 36.00  ? 676  LYS A C   1 
ATOM   5111  O  O   . LYS A 1 676 ? 167.649 163.117 194.152 1.00 36.00  ? 676  LYS A O   1 
ATOM   5112  C  CB  . LYS A 1 676 ? 169.685 165.089 194.345 1.00 36.00  ? 676  LYS A CB  1 
ATOM   5113  C  CG  . LYS A 1 676 ? 170.650 164.193 195.096 1.00 36.00  ? 676  LYS A CG  1 
ATOM   5114  C  CD  . LYS A 1 676 ? 171.277 164.926 196.270 1.00 36.00  ? 676  LYS A CD  1 
ATOM   5115  C  CE  . LYS A 1 676 ? 172.675 164.408 196.565 1.00 36.00  ? 676  LYS A CE  1 
ATOM   5116  N  NZ  . LYS A 1 676 ? 173.180 164.884 197.882 1.00 36.00  ? 676  LYS A NZ  1 
ATOM   5117  N  N   . SER A 1 677 ? 168.520 162.345 192.231 1.00 40.08  ? 677  SER A N   1 
ATOM   5118  C  CA  . SER A 1 677 ? 167.779 161.093 192.274 1.00 40.08  ? 677  SER A CA  1 
ATOM   5119  C  C   . SER A 1 677 ? 168.618 159.992 191.644 1.00 40.08  ? 677  SER A C   1 
ATOM   5120  O  O   . SER A 1 677 ? 169.344 160.234 190.677 1.00 40.08  ? 677  SER A O   1 
ATOM   5121  C  CB  . SER A 1 677 ? 166.435 161.214 191.548 1.00 40.08  ? 677  SER A CB  1 
ATOM   5122  O  OG  . SER A 1 677 ? 165.728 159.987 191.578 1.00 40.08  ? 677  SER A OG  1 
ATOM   5123  N  N   . LEU A 1 678 ? 168.513 158.784 192.201 1.00 37.84  ? 678  LEU A N   1 
ATOM   5124  C  CA  . LEU A 1 678 ? 169.269 157.654 191.676 1.00 37.84  ? 678  LEU A CA  1 
ATOM   5125  C  C   . LEU A 1 678 ? 168.657 157.090 190.399 1.00 37.84  ? 678  LEU A C   1 
ATOM   5126  O  O   . LEU A 1 678 ? 169.387 156.567 189.549 1.00 37.84  ? 678  LEU A O   1 
ATOM   5127  C  CB  . LEU A 1 678 ? 169.376 156.556 192.734 1.00 37.84  ? 678  LEU A CB  1 
ATOM   5128  C  CG  . LEU A 1 678 ? 170.345 156.813 193.889 1.00 37.84  ? 678  LEU A CG  1 
ATOM   5129  C  CD1 . LEU A 1 678 ? 170.386 155.620 194.824 1.00 37.84  ? 678  LEU A CD1 1 
ATOM   5130  C  CD2 . LEU A 1 678 ? 171.731 157.125 193.360 1.00 37.84  ? 678  LEU A CD2 1 
ATOM   5131  N  N   . MET A 1 679 ? 167.333 157.173 190.250 1.00 45.55  ? 679  MET A N   1 
ATOM   5132  C  CA  . MET A 1 679 ? 166.691 156.669 189.038 1.00 45.55  ? 679  MET A CA  1 
ATOM   5133  C  C   . MET A 1 679 ? 167.155 157.437 187.807 1.00 45.55  ? 679  MET A C   1 
ATOM   5134  O  O   . MET A 1 679 ? 167.419 156.839 186.754 1.00 45.55  ? 679  MET A O   1 
ATOM   5135  C  CB  . MET A 1 679 ? 165.172 156.749 189.182 1.00 45.55  ? 679  MET A CB  1 
ATOM   5136  C  CG  . MET A 1 679 ? 164.404 156.235 187.977 1.00 45.55  ? 679  MET A CG  1 
ATOM   5137  S  SD  . MET A 1 679 ? 164.871 154.558 187.510 1.00 45.55  ? 679  MET A SD  1 
ATOM   5138  C  CE  . MET A 1 679 ? 164.057 153.615 188.796 1.00 45.55  ? 679  MET A CE  1 
ATOM   5139  N  N   . VAL A 1 680 ? 167.254 158.763 187.921 1.00 39.94  ? 680  VAL A N   1 
ATOM   5140  C  CA  . VAL A 1 680 ? 167.763 159.577 186.822 1.00 39.94  ? 680  VAL A CA  1 
ATOM   5141  C  C   . VAL A 1 680 ? 169.185 159.163 186.476 1.00 39.94  ? 680  VAL A C   1 
ATOM   5142  O  O   . VAL A 1 680 ? 169.550 159.061 185.298 1.00 39.94  ? 680  VAL A O   1 
ATOM   5143  C  CB  . VAL A 1 680 ? 167.677 161.070 187.187 1.00 39.94  ? 680  VAL A CB  1 
ATOM   5144  C  CG1 . VAL A 1 680 ? 168.281 161.919 186.091 1.00 39.94  ? 680  VAL A CG1 1 
ATOM   5145  C  CG2 . VAL A 1 680 ? 166.235 161.469 187.442 1.00 39.94  ? 680  VAL A CG2 1 
ATOM   5146  N  N   . LEU A 1 681 ? 170.008 158.914 187.497 1.00 40.22  ? 681  LEU A N   1 
ATOM   5147  C  CA  . LEU A 1 681 ? 171.383 158.487 187.264 1.00 40.22  ? 681  LEU A CA  1 
ATOM   5148  C  C   . LEU A 1 681 ? 171.432 157.148 186.539 1.00 40.22  ? 681  LEU A C   1 
ATOM   5149  O  O   . LEU A 1 681 ? 172.242 156.960 185.625 1.00 40.22  ? 681  LEU A O   1 
ATOM   5150  C  CB  . LEU A 1 681 ? 172.130 158.411 188.595 1.00 40.22  ? 681  LEU A CB  1 
ATOM   5151  C  CG  . LEU A 1 681 ? 173.639 158.174 188.584 1.00 40.22  ? 681  LEU A CG  1 
ATOM   5152  C  CD1 . LEU A 1 681 ? 174.273 158.940 189.727 1.00 40.22  ? 681  LEU A CD1 1 
ATOM   5153  C  CD2 . LEU A 1 681 ? 173.960 156.694 188.704 1.00 40.22  ? 681  LEU A CD2 1 
ATOM   5154  N  N   . GLU A 1 682 ? 170.578 156.203 186.935 1.00 42.82  ? 682  GLU A N   1 
ATOM   5155  C  CA  . GLU A 1 682 ? 170.566 154.892 186.291 1.00 42.82  ? 682  GLU A CA  1 
ATOM   5156  C  C   . GLU A 1 682 ? 170.137 154.996 184.830 1.00 42.82  ? 682  GLU A C   1 
ATOM   5157  O  O   . GLU A 1 682 ? 170.749 154.383 183.943 1.00 42.82  ? 682  GLU A O   1 
ATOM   5158  C  CB  . GLU A 1 682 ? 169.646 153.945 187.061 1.00 42.82  ? 682  GLU A CB  1 
ATOM   5159  C  CG  . GLU A 1 682 ? 169.715 152.500 186.610 1.00 42.82  ? 682  GLU A CG  1 
ATOM   5160  C  CD  . GLU A 1 682 ? 168.631 152.154 185.612 1.00 42.82  ? 682  GLU A CD  1 
ATOM   5161  O  OE1 . GLU A 1 682 ? 167.549 152.775 185.671 1.00 42.82  ? 682  GLU A OE1 1 
ATOM   5162  O  OE2 . GLU A 1 682 ? 168.860 151.262 184.769 1.00 42.82  ? 682  GLU A OE2 1 
ATOM   5163  N  N   . GLU A 1 683 ? 169.082 155.771 184.561 1.00 44.55  ? 683  GLU A N   1 
ATOM   5164  C  CA  . GLU A 1 683 ? 168.642 155.953 183.180 1.00 44.55  ? 683  GLU A CA  1 
ATOM   5165  C  C   . GLU A 1 683 ? 169.719 156.638 182.347 1.00 44.55  ? 683  GLU A C   1 
ATOM   5166  O  O   . GLU A 1 683 ? 169.949 156.270 181.187 1.00 44.55  ? 683  GLU A O   1 
ATOM   5167  C  CB  . GLU A 1 683 ? 167.339 156.751 183.143 1.00 44.55  ? 683  GLU A CB  1 
ATOM   5168  C  CG  . GLU A 1 683 ? 166.200 156.105 183.913 1.00 44.55  ? 683  GLU A CG  1 
ATOM   5169  C  CD  . GLU A 1 683 ? 164.859 156.749 183.623 1.00 44.55  ? 683  GLU A CD  1 
ATOM   5170  O  OE1 . GLU A 1 683 ? 164.769 157.524 182.648 1.00 44.55  ? 683  GLU A OE1 1 
ATOM   5171  O  OE2 . GLU A 1 683 ? 163.895 156.479 184.369 1.00 44.55  ? 683  GLU A OE2 1 
ATOM   5172  N  N   . GLY A 1 684 ? 170.392 157.635 182.924 1.00 41.10  ? 684  GLY A N   1 
ATOM   5173  C  CA  . GLY A 1 684 ? 171.483 158.280 182.217 1.00 41.10  ? 684  GLY A CA  1 
ATOM   5174  C  C   . GLY A 1 684 ? 172.630 157.333 181.931 1.00 41.10  ? 684  GLY A C   1 
ATOM   5175  O  O   . GLY A 1 684 ? 173.250 157.401 180.869 1.00 41.10  ? 684  GLY A O   1 
ATOM   5176  N  N   . VAL A 1 685 ? 172.939 156.448 182.880 1.00 39.60  ? 685  VAL A N   1 
ATOM   5177  C  CA  . VAL A 1 685 ? 173.997 155.464 182.667 1.00 39.60  ? 685  VAL A CA  1 
ATOM   5178  C  C   . VAL A 1 685 ? 173.630 154.545 181.510 1.00 39.60  ? 685  VAL A C   1 
ATOM   5179  O  O   . VAL A 1 685 ? 174.458 154.248 180.641 1.00 39.60  ? 685  VAL A O   1 
ATOM   5180  C  CB  . VAL A 1 685 ? 174.264 154.670 183.959 1.00 39.60  ? 685  VAL A CB  1 
ATOM   5181  C  CG1 . VAL A 1 685 ? 174.975 153.366 183.646 1.00 39.60  ? 685  VAL A CG1 1 
ATOM   5182  C  CG2 . VAL A 1 685 ? 175.083 155.498 184.932 1.00 39.60  ? 685  VAL A CG2 1 
ATOM   5183  N  N   . ILE A 1 686 ? 172.375 154.093 181.477 1.00 40.88  ? 686  ILE A N   1 
ATOM   5184  C  CA  . ILE A 1 686 ? 171.931 153.228 180.386 1.00 40.88  ? 686  ILE A CA  1 
ATOM   5185  C  C   . ILE A 1 686 ? 172.052 153.949 179.047 1.00 40.88  ? 686  ILE A C   1 
ATOM   5186  O  O   . ILE A 1 686 ? 172.569 153.394 178.065 1.00 40.88  ? 686  ILE A O   1 
ATOM   5187  C  CB  . ILE A 1 686 ? 170.493 152.742 180.642 1.00 40.88  ? 686  ILE A CB  1 
ATOM   5188  C  CG1 . ILE A 1 686 ? 170.457 151.791 181.841 1.00 40.88  ? 686  ILE A CG1 1 
ATOM   5189  C  CG2 . ILE A 1 686 ? 169.927 152.069 179.404 1.00 40.88  ? 686  ILE A CG2 1 
ATOM   5190  C  CD1 . ILE A 1 686 ? 171.429 150.637 181.734 1.00 40.88  ? 686  ILE A CD1 1 
ATOM   5191  N  N   . GLU A 1 687 ? 171.595 155.202 178.988 1.00 40.47  ? 687  GLU A N   1 
ATOM   5192  C  CA  . GLU A 1 687 ? 171.635 155.927 177.723 1.00 40.47  ? 687  GLU A CA  1 
ATOM   5193  C  C   . GLU A 1 687 ? 173.067 156.232 177.286 1.00 40.47  ? 687  GLU A C   1 
ATOM   5194  O  O   . GLU A 1 687 ? 173.366 156.193 176.087 1.00 40.47  ? 687  GLU A O   1 
ATOM   5195  C  CB  . GLU A 1 687 ? 170.820 157.216 177.832 1.00 40.47  ? 687  GLU A CB  1 
ATOM   5196  C  CG  . GLU A 1 687 ? 170.540 157.893 176.500 1.00 40.47  ? 687  GLU A CG  1 
ATOM   5197  C  CD  . GLU A 1 687 ? 171.688 158.755 176.030 1.00 40.47  ? 687  GLU A CD  1 
ATOM   5198  O  OE1 . GLU A 1 687 ? 172.437 159.259 176.889 1.00 40.47  ? 687  GLU A OE1 1 
ATOM   5199  O  OE2 . GLU A 1 687 ? 171.843 158.928 174.803 1.00 40.47  ? 687  GLU A OE2 1 
ATOM   5200  N  N   . GLY A 1 688 ? 173.962 156.528 178.232 1.00 40.60  ? 688  GLY A N   1 
ATOM   5201  C  CA  . GLY A 1 688 ? 175.361 156.713 177.890 1.00 40.60  ? 688  GLY A CA  1 
ATOM   5202  C  C   . GLY A 1 688 ? 176.031 155.448 177.400 1.00 40.60  ? 688  GLY A C   1 
ATOM   5203  O  O   . GLY A 1 688 ? 176.866 155.499 176.490 1.00 40.60  ? 688  GLY A O   1 
ATOM   5204  N  N   . ARG A 1 689 ? 175.683 154.301 177.991 1.00 43.26  ? 689  ARG A N   1 
ATOM   5205  C  CA  . ARG A 1 689 ? 176.159 153.030 177.458 1.00 43.26  ? 689  ARG A CA  1 
ATOM   5206  C  C   . ARG A 1 689 ? 175.684 152.838 176.026 1.00 43.26  ? 689  ARG A C   1 
ATOM   5207  O  O   . ARG A 1 689 ? 176.449 152.391 175.162 1.00 43.26  ? 689  ARG A O   1 
ATOM   5208  C  CB  . ARG A 1 689 ? 175.684 151.872 178.336 1.00 43.26  ? 689  ARG A CB  1 
ATOM   5209  C  CG  . ARG A 1 689 ? 176.241 151.874 179.749 1.00 43.26  ? 689  ARG A CG  1 
ATOM   5210  C  CD  . ARG A 1 689 ? 175.996 150.539 180.433 1.00 43.26  ? 689  ARG A CD  1 
ATOM   5211  N  NE  . ARG A 1 689 ? 176.709 150.429 181.699 1.00 43.26  ? 689  ARG A NE  1 
ATOM   5212  C  CZ  . ARG A 1 689 ? 176.254 149.772 182.756 1.00 43.26  ? 689  ARG A CZ  1 
ATOM   5213  N  NH1 . ARG A 1 689 ? 175.088 149.148 182.733 1.00 43.26  ? 689  ARG A NH1 1 
ATOM   5214  N  NH2 . ARG A 1 689 ? 176.985 149.743 183.867 1.00 43.26  ? 689  ARG A NH2 1 
ATOM   5215  N  N   . ARG A 1 690 ? 174.423 153.184 175.754 1.00 45.04  ? 690  ARG A N   1 
ATOM   5216  C  CA  . ARG A 1 690 ? 173.914 153.100 174.387 1.00 45.04  ? 690  ARG A CA  1 
ATOM   5217  C  C   . ARG A 1 690 ? 174.703 154.002 173.444 1.00 45.04  ? 690  ARG A C   1 
ATOM   5218  O  O   . ARG A 1 690 ? 175.045 153.600 172.326 1.00 45.04  ? 690  ARG A O   1 
ATOM   5219  C  CB  . ARG A 1 690 ? 172.432 153.471 174.352 1.00 45.04  ? 690  ARG A CB  1 
ATOM   5220  C  CG  . ARG A 1 690 ? 171.491 152.345 174.730 1.00 45.04  ? 690  ARG A CG  1 
ATOM   5221  C  CD  . ARG A 1 690 ? 170.060 152.696 174.360 1.00 45.04  ? 690  ARG A CD  1 
ATOM   5222  N  NE  . ARG A 1 690 ? 169.093 152.099 175.273 1.00 45.04  ? 690  ARG A NE  1 
ATOM   5223  C  CZ  . ARG A 1 690 ? 168.060 152.746 175.794 1.00 45.04  ? 690  ARG A CZ  1 
ATOM   5224  N  NH1 . ARG A 1 690 ? 167.830 154.019 175.515 1.00 45.04  ? 690  ARG A NH1 1 
ATOM   5225  N  NH2 . ARG A 1 690 ? 167.238 152.101 176.616 1.00 45.04  ? 690  ARG A NH2 1 
ATOM   5226  N  N   . THR A 1 691 ? 174.997 155.229 173.879 1.00 39.44  ? 691  THR A N   1 
ATOM   5227  C  CA  . THR A 1 691 ? 175.731 156.168 173.034 1.00 39.44  ? 691  THR A CA  1 
ATOM   5228  C  C   . THR A 1 691 ? 177.135 155.658 172.723 1.00 39.44  ? 691  THR A C   1 
ATOM   5229  O  O   . THR A 1 691 ? 177.592 155.710 171.572 1.00 39.44  ? 691  THR A O   1 
ATOM   5230  C  CB  . THR A 1 691 ? 175.798 157.537 173.710 1.00 39.44  ? 691  THR A CB  1 
ATOM   5231  O  OG1 . THR A 1 691 ? 174.475 158.070 173.846 1.00 39.44  ? 691  THR A OG1 1 
ATOM   5232  C  CG2 . THR A 1 691 ? 176.642 158.495 172.888 1.00 39.44  ? 691  THR A CG2 1 
ATOM   5233  N  N   . PHE A 1 692 ? 177.841 155.165 173.742 1.00 40.30  ? 692  PHE A N   1 
ATOM   5234  C  CA  . PHE A 1 692 ? 179.191 154.664 173.508 1.00 40.30  ? 692  PHE A CA  1 
ATOM   5235  C  C   . PHE A 1 692 ? 179.171 153.418 172.631 1.00 40.30  ? 692  PHE A C   1 
ATOM   5236  O  O   . PHE A 1 692 ? 180.059 153.230 171.789 1.00 40.30  ? 692  PHE A O   1 
ATOM   5237  C  CB  . PHE A 1 692 ? 179.895 154.378 174.831 1.00 40.30  ? 692  PHE A CB  1 
ATOM   5238  C  CG  . PHE A 1 692 ? 181.388 154.310 174.712 1.00 40.30  ? 692  PHE A CG  1 
ATOM   5239  C  CD1 . PHE A 1 692 ? 182.122 155.445 174.417 1.00 40.30  ? 692  PHE A CD1 1 
ATOM   5240  C  CD2 . PHE A 1 692 ? 182.056 153.111 174.880 1.00 40.30  ? 692  PHE A CD2 1 
ATOM   5241  C  CE1 . PHE A 1 692 ? 183.496 155.387 174.302 1.00 40.30  ? 692  PHE A CE1 1 
ATOM   5242  C  CE2 . PHE A 1 692 ? 183.429 153.046 174.766 1.00 40.30  ? 692  PHE A CE2 1 
ATOM   5243  C  CZ  . PHE A 1 692 ? 184.151 154.186 174.476 1.00 40.30  ? 692  PHE A CZ  1 
ATOM   5244  N  N   . ALA A 1 693 ? 178.164 152.559 172.809 1.00 40.86  ? 693  ALA A N   1 
ATOM   5245  C  CA  . ALA A 1 693 ? 178.020 151.406 171.929 1.00 40.86  ? 693  ALA A CA  1 
ATOM   5246  C  C   . ALA A 1 693 ? 177.794 151.846 170.490 1.00 40.86  ? 693  ALA A C   1 
ATOM   5247  O  O   . ALA A 1 693 ? 178.344 151.249 169.558 1.00 40.86  ? 693  ALA A O   1 
ATOM   5248  C  CB  . ALA A 1 693 ? 176.874 150.518 172.409 1.00 40.86  ? 693  ALA A CB  1 
ATOM   5249  N  N   . ASN A 1 694 ? 176.985 152.890 170.290 1.00 43.99  ? 694  ASN A N   1 
ATOM   5250  C  CA  . ASN A 1 694 ? 176.768 153.415 168.946 1.00 43.99  ? 694  ASN A CA  1 
ATOM   5251  C  C   . ASN A 1 694 ? 178.068 153.915 168.334 1.00 43.99  ? 694  ASN A C   1 
ATOM   5252  O  O   . ASN A 1 694 ? 178.354 153.650 167.160 1.00 43.99  ? 694  ASN A O   1 
ATOM   5253  C  CB  . ASN A 1 694 ? 175.736 154.540 168.981 1.00 43.99  ? 694  ASN A CB  1 
ATOM   5254  C  CG  . ASN A 1 694 ? 174.325 154.040 168.786 1.00 43.99  ? 694  ASN A CG  1 
ATOM   5255  O  OD1 . ASN A 1 694 ? 174.112 152.919 168.326 1.00 43.99  ? 694  ASN A OD1 1 
ATOM   5256  N  ND2 . ASN A 1 694 ? 173.350 154.870 169.132 1.00 43.99  ? 694  ASN A ND2 1 
ATOM   5257  N  N   . MET A 1 695 ? 178.865 154.648 169.113 1.00 37.67  ? 695  MET A N   1 
ATOM   5258  C  CA  . MET A 1 695 ? 180.134 155.157 168.599 1.00 37.67  ? 695  MET A CA  1 
ATOM   5259  C  C   . MET A 1 695 ? 181.068 154.015 168.211 1.00 37.67  ? 695  MET A C   1 
ATOM   5260  O  O   . MET A 1 695 ? 181.686 154.030 167.134 1.00 37.67  ? 695  MET A O   1 
ATOM   5261  C  CB  . MET A 1 695 ? 180.792 156.059 169.642 1.00 37.67  ? 695  MET A CB  1 
ATOM   5262  C  CG  . MET A 1 695 ? 181.912 156.923 169.100 1.00 37.67  ? 695  MET A CG  1 
ATOM   5263  S  SD  . MET A 1 695 ? 183.024 157.477 170.402 1.00 37.67  ? 695  MET A SD  1 
ATOM   5264  C  CE  . MET A 1 695 ? 184.068 156.035 170.584 1.00 37.67  ? 695  MET A CE  1 
ATOM   5265  N  N   . LEU A 1 696 ? 181.177 153.007 169.081 1.00 40.52  ? 696  LEU A N   1 
ATOM   5266  C  CA  . LEU A 1 696 ? 182.042 151.870 168.786 1.00 40.52  ? 696  LEU A CA  1 
ATOM   5267  C  C   . LEU A 1 696 ? 181.565 151.123 167.549 1.00 40.52  ? 696  LEU A C   1 
ATOM   5268  O  O   . LEU A 1 696 ? 182.378 150.704 166.718 1.00 40.52  ? 696  LEU A O   1 
ATOM   5269  C  CB  . LEU A 1 696 ? 182.108 150.932 169.990 1.00 40.52  ? 696  LEU A CB  1 
ATOM   5270  C  CG  . LEU A 1 696 ? 182.910 151.441 171.188 1.00 40.52  ? 696  LEU A CG  1 
ATOM   5271  C  CD1 . LEU A 1 696 ? 182.940 150.403 172.295 1.00 40.52  ? 696  LEU A CD1 1 
ATOM   5272  C  CD2 . LEU A 1 696 ? 184.320 151.811 170.761 1.00 40.52  ? 696  LEU A CD2 1 
ATOM   5273  N  N   . LYS A 1 697 ? 180.249 150.947 167.412 1.00 46.16  ? 697  LYS A N   1 
ATOM   5274  C  CA  . LYS A 1 697 ? 179.705 150.281 166.234 1.00 46.16  ? 697  LYS A CA  1 
ATOM   5275  C  C   . LYS A 1 697 ? 180.015 151.067 164.968 1.00 46.16  ? 697  LYS A C   1 
ATOM   5276  O  O   . LYS A 1 697 ? 180.382 150.484 163.940 1.00 46.16  ? 697  LYS A O   1 
ATOM   5277  C  CB  . LYS A 1 697 ? 178.198 150.090 166.400 1.00 46.16  ? 697  LYS A CB  1 
ATOM   5278  C  CG  . LYS A 1 697 ? 177.432 149.929 165.102 1.00 46.16  ? 697  LYS A CG  1 
ATOM   5279  C  CD  . LYS A 1 697 ? 176.002 150.424 165.244 1.00 46.16  ? 697  LYS A CD  1 
ATOM   5280  C  CE  . LYS A 1 697 ? 175.327 149.823 166.463 1.00 46.16  ? 697  LYS A CE  1 
ATOM   5281  N  NZ  . LYS A 1 697 ? 173.934 150.319 166.620 1.00 46.16  ? 697  LYS A NZ  1 
ATOM   5282  N  N   . TYR A 1 698 ? 179.874 152.394 165.025 1.00 44.30  ? 698  TYR A N   1 
ATOM   5283  C  CA  . TYR A 1 698 ? 180.218 153.243 163.889 1.00 44.30  ? 698  TYR A CA  1 
ATOM   5284  C  C   . TYR A 1 698 ? 181.658 153.008 163.455 1.00 44.30  ? 698  TYR A C   1 
ATOM   5285  O  O   . TYR A 1 698 ? 181.940 152.734 162.279 1.00 44.30  ? 698  TYR A O   1 
ATOM   5286  C  CB  . TYR A 1 698 ? 180.023 154.713 164.264 1.00 44.30  ? 698  TYR A CB  1 
ATOM   5287  C  CG  . TYR A 1 698 ? 180.025 155.664 163.090 1.00 44.30  ? 698  TYR A CG  1 
ATOM   5288  C  CD1 . TYR A 1 698 ? 178.853 155.985 162.433 1.00 44.30  ? 698  TYR A CD1 1 
ATOM   5289  C  CD2 . TYR A 1 698 ? 181.206 156.215 162.619 1.00 44.30  ? 698  TYR A CD2 1 
ATOM   5290  C  CE1 . TYR A 1 698 ? 178.848 156.850 161.362 1.00 44.30  ? 698  TYR A CE1 1 
ATOM   5291  C  CE2 . TYR A 1 698 ? 181.211 157.076 161.540 1.00 44.30  ? 698  TYR A CE2 1 
ATOM   5292  C  CZ  . TYR A 1 698 ? 180.029 157.390 160.916 1.00 44.30  ? 698  TYR A CZ  1 
ATOM   5293  O  OH  . TYR A 1 698 ? 180.029 158.248 159.842 1.00 44.30  ? 698  TYR A OH  1 
ATOM   5294  N  N   . ILE A 1 699 ? 182.584 153.110 164.413 1.00 43.92  ? 699  ILE A N   1 
ATOM   5295  C  CA  . ILE A 1 699 ? 184.001 152.971 164.088 1.00 43.92  ? 699  ILE A CA  1 
ATOM   5296  C  C   . ILE A 1 699 ? 184.280 151.586 163.519 1.00 43.92  ? 699  ILE A C   1 
ATOM   5297  O  O   . ILE A 1 699 ? 184.957 151.441 162.492 1.00 43.92  ? 699  ILE A O   1 
ATOM   5298  C  CB  . ILE A 1 699 ? 184.872 153.256 165.324 1.00 43.92  ? 699  ILE A CB  1 
ATOM   5299  C  CG1 . ILE A 1 699 ? 184.569 154.645 165.886 1.00 43.92  ? 699  ILE A CG1 1 
ATOM   5300  C  CG2 . ILE A 1 699 ? 186.344 153.129 164.975 1.00 43.92  ? 699  ILE A CG2 1 
ATOM   5301  C  CD1 . ILE A 1 699 ? 185.298 154.949 167.173 1.00 43.92  ? 699  ILE A CD1 1 
ATOM   5302  N  N   . LYS A 1 700 ? 183.742 150.551 164.168 1.00 48.45  ? 700  LYS A N   1 
ATOM   5303  C  CA  . LYS A 1 700 ? 183.997 149.179 163.743 1.00 48.45  ? 700  LYS A CA  1 
ATOM   5304  C  C   . LYS A 1 700 ? 183.509 148.944 162.321 1.00 48.45  ? 700  LYS A C   1 
ATOM   5305  O  O   . LYS A 1 700 ? 184.246 148.426 161.476 1.00 48.45  ? 700  LYS A O   1 
ATOM   5306  C  CB  . LYS A 1 700 ? 183.324 148.203 164.709 1.00 48.45  ? 700  LYS A CB  1 
ATOM   5307  C  CG  . LYS A 1 700 ? 184.056 148.011 166.025 1.00 48.45  ? 700  LYS A CG  1 
ATOM   5308  C  CD  . LYS A 1 700 ? 183.358 146.978 166.898 1.00 48.45  ? 700  LYS A CD  1 
ATOM   5309  C  CE  . LYS A 1 700 ? 181.843 147.119 166.826 1.00 48.45  ? 700  LYS A CE  1 
ATOM   5310  N  NZ  . LYS A 1 700 ? 181.140 146.054 167.594 1.00 48.45  ? 700  LYS A NZ  1 
ATOM   5311  N  N   . MET A 1 701 ? 182.261 149.325 162.038 1.00 48.71  ? 701  MET A N   1 
ATOM   5312  C  CA  . MET A 1 701 ? 181.692 149.061 160.721 1.00 48.71  ? 701  MET A CA  1 
ATOM   5313  C  C   . MET A 1 701 ? 182.423 149.835 159.634 1.00 48.71  ? 701  MET A C   1 
ATOM   5314  O  O   . MET A 1 701 ? 182.764 149.269 158.584 1.00 48.71  ? 701  MET A O   1 
ATOM   5315  C  CB  . MET A 1 701 ? 180.204 149.401 160.717 1.00 48.71  ? 701  MET A CB  1 
ATOM   5316  C  CG  . MET A 1 701 ? 179.378 148.542 161.654 1.00 48.71  ? 701  MET A CG  1 
ATOM   5317  S  SD  . MET A 1 701 ? 177.627 148.946 161.590 1.00 48.71  ? 701  MET A SD  1 
ATOM   5318  C  CE  . MET A 1 701 ? 177.705 150.734 161.540 1.00 48.71  ? 701  MET A CE  1 
ATOM   5319  N  N   . THR A 1 702 ? 182.678 151.128 159.860 1.00 51.43  ? 702  THR A N   1 
ATOM   5320  C  CA  . THR A 1 702 ? 183.366 151.918 158.844 1.00 51.43  ? 702  THR A CA  1 
ATOM   5321  C  C   . THR A 1 702 ? 184.755 151.357 158.565 1.00 51.43  ? 702  THR A C   1 
ATOM   5322  O  O   . THR A 1 702 ? 185.137 151.158 157.402 1.00 51.43  ? 702  THR A O   1 
ATOM   5323  C  CB  . THR A 1 702 ? 183.452 153.379 159.283 1.00 51.43  ? 702  THR A CB  1 
ATOM   5324  O  OG1 . THR A 1 702 ? 182.132 153.932 159.362 1.00 51.43  ? 702  THR A OG1 1 
ATOM   5325  C  CG2 . THR A 1 702 ? 184.273 154.184 158.290 1.00 51.43  ? 702  THR A CG2 1 
ATOM   5326  N  N   . ALA A 1 703 ? 185.517 151.073 159.626 1.00 53.80  ? 703  ALA A N   1 
ATOM   5327  C  CA  . ALA A 1 703 ? 186.867 150.556 159.443 1.00 53.80  ? 703  ALA A CA  1 
ATOM   5328  C  C   . ALA A 1 703 ? 186.852 149.205 158.743 1.00 53.80  ? 703  ALA A C   1 
ATOM   5329  O  O   . ALA A 1 703 ? 187.659 148.963 157.840 1.00 53.80  ? 703  ALA A O   1 
ATOM   5330  C  CB  . ALA A 1 703 ? 187.575 150.454 160.793 1.00 53.80  ? 703  ALA A CB  1 
ATOM   5331  N  N   . SER A 1 704 ? 185.938 148.314 159.135 1.00 56.15  ? 704  SER A N   1 
ATOM   5332  C  CA  . SER A 1 704 ? 185.894 146.987 158.533 1.00 56.15  ? 704  SER A CA  1 
ATOM   5333  C  C   . SER A 1 704 ? 185.558 147.065 157.050 1.00 56.15  ? 704  SER A C   1 
ATOM   5334  O  O   . SER A 1 704 ? 186.212 146.422 156.221 1.00 56.15  ? 704  SER A O   1 
ATOM   5335  C  CB  . SER A 1 704 ? 184.881 146.111 159.270 1.00 56.15  ? 704  SER A CB  1 
ATOM   5336  O  OG  . SER A 1 704 ? 183.563 146.371 158.823 1.00 56.15  ? 704  SER A OG  1 
ATOM   5337  N  N   . SER A 1 705 ? 184.545 147.860 156.691 1.00 56.60  ? 705  SER A N   1 
ATOM   5338  C  CA  . SER A 1 705 ? 184.157 147.953 155.287 1.00 56.60  ? 705  SER A CA  1 
ATOM   5339  C  C   . SER A 1 705 ? 185.266 148.569 154.442 1.00 56.60  ? 705  SER A C   1 
ATOM   5340  O  O   . SER A 1 705 ? 185.585 148.068 153.353 1.00 56.60  ? 705  SER A O   1 
ATOM   5341  C  CB  . SER A 1 705 ? 182.868 148.761 155.153 1.00 56.60  ? 705  SER A CB  1 
ATOM   5342  O  OG  . SER A 1 705 ? 181.741 147.981 155.510 1.00 56.60  ? 705  SER A OG  1 
ATOM   5343  N  N   . ASN A 1 706 ? 185.878 149.652 154.930 1.00 60.04  ? 706  ASN A N   1 
ATOM   5344  C  CA  . ASN A 1 706 ? 186.924 150.298 154.147 1.00 60.04  ? 706  ASN A CA  1 
ATOM   5345  C  C   . ASN A 1 706 ? 188.169 149.423 154.041 1.00 60.04  ? 706  ASN A C   1 
ATOM   5346  O  O   . ASN A 1 706 ? 188.806 149.380 152.981 1.00 60.04  ? 706  ASN A O   1 
ATOM   5347  C  CB  . ASN A 1 706 ? 187.238 151.662 154.754 1.00 60.04  ? 706  ASN A CB  1 
ATOM   5348  C  CG  . ASN A 1 706 ? 186.010 152.555 154.820 1.00 60.04  ? 706  ASN A CG  1 
ATOM   5349  O  OD1 . ASN A 1 706 ? 184.900 152.116 154.519 1.00 60.04  ? 706  ASN A OD1 1 
ATOM   5350  N  ND2 . ASN A 1 706 ? 186.197 153.800 155.232 1.00 60.04  ? 706  ASN A ND2 1 
ATOM   5351  N  N   . PHE A 1 707 ? 188.516 148.700 155.109 1.00 62.34  ? 707  PHE A N   1 
ATOM   5352  C  CA  . PHE A 1 707 ? 189.635 147.768 155.042 1.00 62.34  ? 707  PHE A CA  1 
ATOM   5353  C  C   . PHE A 1 707 ? 189.350 146.631 154.073 1.00 62.34  ? 707  PHE A C   1 
ATOM   5354  O  O   . PHE A 1 707 ? 190.252 146.170 153.367 1.00 62.34  ? 707  PHE A O   1 
ATOM   5355  C  CB  . PHE A 1 707 ? 189.940 147.216 156.432 1.00 62.34  ? 707  PHE A CB  1 
ATOM   5356  C  CG  . PHE A 1 707 ? 190.815 146.001 156.419 1.00 62.34  ? 707  PHE A CG  1 
ATOM   5357  C  CD1 . PHE A 1 707 ? 192.139 146.090 156.038 1.00 62.34  ? 707  PHE A CD1 1 
ATOM   5358  C  CD2 . PHE A 1 707 ? 190.308 144.764 156.777 1.00 62.34  ? 707  PHE A CD2 1 
ATOM   5359  C  CE1 . PHE A 1 707 ? 192.943 144.972 156.025 1.00 62.34  ? 707  PHE A CE1 1 
ATOM   5360  C  CE2 . PHE A 1 707 ? 191.110 143.641 156.764 1.00 62.34  ? 707  PHE A CE2 1 
ATOM   5361  C  CZ  . PHE A 1 707 ? 192.430 143.746 156.387 1.00 62.34  ? 707  PHE A CZ  1 
ATOM   5362  N  N   . GLY A 1 708 ? 188.106 146.149 154.038 1.00 64.98  ? 708  GLY A N   1 
ATOM   5363  C  CA  . GLY A 1 708 ? 187.752 145.131 153.064 1.00 64.98  ? 708  GLY A CA  1 
ATOM   5364  C  C   . GLY A 1 708 ? 187.894 145.624 151.638 1.00 64.98  ? 708  GLY A C   1 
ATOM   5365  O  O   . GLY A 1 708 ? 188.399 144.907 150.768 1.00 64.98  ? 708  GLY A O   1 
ATOM   5366  N  N   . ASN A 1 709 ? 187.456 146.858 151.378 1.00 63.38  ? 709  ASN A N   1 
ATOM   5367  C  CA  . ASN A 1 709 ? 187.637 147.433 150.048 1.00 63.38  ? 709  ASN A CA  1 
ATOM   5368  C  C   . ASN A 1 709 ? 189.117 147.549 149.693 1.00 63.38  ? 709  ASN A C   1 
ATOM   5369  O  O   . ASN A 1 709 ? 189.523 147.227 148.568 1.00 63.38  ? 709  ASN A O   1 
ATOM   5370  C  CB  . ASN A 1 709 ? 186.956 148.798 149.964 1.00 63.38  ? 709  ASN A CB  1 
ATOM   5371  C  CG  . ASN A 1 709 ? 185.444 148.698 150.013 1.00 63.38  ? 709  ASN A CG  1 
ATOM   5372  O  OD1 . ASN A 1 709 ? 184.878 147.610 149.909 1.00 63.38  ? 709  ASN A OD1 1 
ATOM   5373  N  ND2 . ASN A 1 709 ? 184.781 149.837 150.171 1.00 63.38  ? 709  ASN A ND2 1 
ATOM   5374  N  N   . VAL A 1 710 ? 189.938 148.000 150.646 1.00 67.01  ? 710  VAL A N   1 
ATOM   5375  C  CA  . VAL A 1 710 ? 191.373 148.125 150.395 1.00 67.01  ? 710  VAL A CA  1 
ATOM   5376  C  C   . VAL A 1 710 ? 191.990 146.763 150.105 1.00 67.01  ? 710  VAL A C   1 
ATOM   5377  O  O   . VAL A 1 710 ? 192.822 146.622 149.201 1.00 67.01  ? 710  VAL A O   1 
ATOM   5378  C  CB  . VAL A 1 710 ? 192.068 148.819 151.581 1.00 67.01  ? 710  VAL A CB  1 
ATOM   5379  C  CG1 . VAL A 1 710 ? 193.578 148.775 151.415 1.00 67.01  ? 710  VAL A CG1 1 
ATOM   5380  C  CG2 . VAL A 1 710 ? 191.596 150.254 151.702 1.00 67.01  ? 710  VAL A CG2 1 
ATOM   5381  N  N   . PHE A 1 711 ? 191.605 145.742 150.873 1.00 69.44  ? 711  PHE A N   1 
ATOM   5382  C  CA  . PHE A 1 711 ? 192.141 144.403 150.654 1.00 69.44  ? 711  PHE A CA  1 
ATOM   5383  C  C   . PHE A 1 711 ? 191.741 143.865 149.287 1.00 69.44  ? 711  PHE A C   1 
ATOM   5384  O  O   . PHE A 1 711 ? 192.557 143.246 148.592 1.00 69.44  ? 711  PHE A O   1 
ATOM   5385  C  CB  . PHE A 1 711 ? 191.669 143.460 151.760 1.00 69.44  ? 711  PHE A CB  1 
ATOM   5386  C  CG  . PHE A 1 711 ? 192.364 142.129 151.758 1.00 69.44  ? 711  PHE A CG  1 
ATOM   5387  C  CD1 . PHE A 1 711 ? 193.746 142.055 151.752 1.00 69.44  ? 711  PHE A CD1 1 
ATOM   5388  C  CD2 . PHE A 1 711 ? 191.635 140.952 151.765 1.00 69.44  ? 711  PHE A CD2 1 
ATOM   5389  C  CE1 . PHE A 1 711 ? 194.389 140.833 151.752 1.00 69.44  ? 711  PHE A CE1 1 
ATOM   5390  C  CE2 . PHE A 1 711 ? 192.272 139.727 151.764 1.00 69.44  ? 711  PHE A CE2 1 
ATOM   5391  C  CZ  . PHE A 1 711 ? 193.651 139.667 151.758 1.00 69.44  ? 711  PHE A CZ  1 
ATOM   5392  N  N   . SER A 1 712 ? 190.483 144.081 148.890 1.00 71.39  ? 712  SER A N   1 
ATOM   5393  C  CA  . SER A 1 712 ? 190.040 143.654 147.567 1.00 71.39  ? 712  SER A CA  1 
ATOM   5394  C  C   . SER A 1 712 ? 190.856 144.329 146.476 1.00 71.39  ? 712  SER A C   1 
ATOM   5395  O  O   . SER A 1 712 ? 191.315 143.673 145.530 1.00 71.39  ? 712  SER A O   1 
ATOM   5396  C  CB  . SER A 1 712 ? 188.557 143.970 147.383 1.00 71.39  ? 712  SER A CB  1 
ATOM   5397  O  OG  . SER A 1 712 ? 187.806 143.585 148.518 1.00 71.39  ? 712  SER A OG  1 
ATOM   5398  N  N   . VAL A 1 713 ? 191.054 145.643 146.600 1.00 71.74  ? 713  VAL A N   1 
ATOM   5399  C  CA  . VAL A 1 713 ? 191.860 146.374 145.627 1.00 71.74  ? 713  VAL A CA  1 
ATOM   5400  C  C   . VAL A 1 713 ? 193.273 145.813 145.572 1.00 71.74  ? 713  VAL A C   1 
ATOM   5401  O  O   . VAL A 1 713 ? 193.834 145.605 144.489 1.00 71.74  ? 713  VAL A O   1 
ATOM   5402  C  CB  . VAL A 1 713 ? 191.860 147.875 145.962 1.00 71.74  ? 713  VAL A CB  1 
ATOM   5403  C  CG1 . VAL A 1 713 ? 192.935 148.583 145.176 1.00 71.74  ? 713  VAL A CG1 1 
ATOM   5404  C  CG2 . VAL A 1 713 ? 190.499 148.480 145.665 1.00 71.74  ? 713  VAL A CG2 1 
ATOM   5405  N  N   . LEU A 1 714 ? 193.870 145.555 146.736 1.00 73.91  ? 714  LEU A N   1 
ATOM   5406  C  CA  . LEU A 1 714 ? 195.245 145.070 146.774 1.00 73.91  ? 714  LEU A CA  1 
ATOM   5407  C  C   . LEU A 1 714 ? 195.374 143.702 146.117 1.00 73.91  ? 714  LEU A C   1 
ATOM   5408  O  O   . LEU A 1 714 ? 196.317 143.461 145.353 1.00 73.91  ? 714  LEU A O   1 
ATOM   5409  C  CB  . LEU A 1 714 ? 195.739 145.022 148.221 1.00 73.91  ? 714  LEU A CB  1 
ATOM   5410  C  CG  . LEU A 1 714 ? 197.224 144.739 148.454 1.00 73.91  ? 714  LEU A CG  1 
ATOM   5411  C  CD1 . LEU A 1 714 ? 197.752 145.609 149.583 1.00 73.91  ? 714  LEU A CD1 1 
ATOM   5412  C  CD2 . LEU A 1 714 ? 197.458 143.269 148.764 1.00 73.91  ? 714  LEU A CD2 1 
ATOM   5413  N  N   . VAL A 1 715 ? 194.442 142.790 146.401 1.00 76.03  ? 715  VAL A N   1 
ATOM   5414  C  CA  . VAL A 1 715 ? 194.591 141.425 145.902 1.00 76.03  ? 715  VAL A CA  1 
ATOM   5415  C  C   . VAL A 1 715 ? 194.259 141.347 144.415 1.00 76.03  ? 715  VAL A C   1 
ATOM   5416  O  O   . VAL A 1 715 ? 194.916 140.619 143.661 1.00 76.03  ? 715  VAL A O   1 
ATOM   5417  C  CB  . VAL A 1 715 ? 193.742 140.440 146.727 1.00 76.03  ? 715  VAL A CB  1 
ATOM   5418  C  CG1 . VAL A 1 715 ? 194.254 140.365 148.160 1.00 76.03  ? 715  VAL A CG1 1 
ATOM   5419  C  CG2 . VAL A 1 715 ? 192.266 140.807 146.686 1.00 76.03  ? 715  VAL A CG2 1 
ATOM   5420  N  N   . ALA A 1 716 ? 193.245 142.086 143.963 1.00 78.93  ? 716  ALA A N   1 
ATOM   5421  C  CA  . ALA A 1 716 ? 192.693 141.884 142.628 1.00 78.93  ? 716  ALA A CA  1 
ATOM   5422  C  C   . ALA A 1 716 ? 193.225 142.862 141.586 1.00 78.93  ? 716  ALA A C   1 
ATOM   5423  O  O   . ALA A 1 716 ? 192.803 142.800 140.427 1.00 78.93  ? 716  ALA A O   1 
ATOM   5424  C  CB  . ALA A 1 716 ? 191.167 141.959 142.679 1.00 78.93  ? 716  ALA A CB  1 
ATOM   5425  N  N   . SER A 1 717 ? 194.137 143.762 141.958 1.00 80.85  ? 717  SER A N   1 
ATOM   5426  C  CA  . SER A 1 717 ? 194.622 144.744 140.993 1.00 80.85  ? 717  SER A CA  1 
ATOM   5427  C  C   . SER A 1 717 ? 195.622 144.151 140.008 1.00 80.85  ? 717  SER A C   1 
ATOM   5428  O  O   . SER A 1 717 ? 195.681 144.593 138.855 1.00 80.85  ? 717  SER A O   1 
ATOM   5429  C  CB  . SER A 1 717 ? 195.258 145.931 141.718 1.00 80.85  ? 717  SER A CB  1 
ATOM   5430  O  OG  . SER A 1 717 ? 196.586 145.635 142.111 1.00 80.85  ? 717  SER A OG  1 
ATOM   5431  N  N   . ALA A 1 718 ? 196.413 143.165 140.438 1.00 84.67  ? 718  ALA A N   1 
ATOM   5432  C  CA  . ALA A 1 718 ? 197.498 142.664 139.599 1.00 84.67  ? 718  ALA A CA  1 
ATOM   5433  C  C   . ALA A 1 718 ? 196.975 141.988 138.337 1.00 84.67  ? 718  ALA A C   1 
ATOM   5434  O  O   . ALA A 1 718 ? 197.507 142.210 137.243 1.00 84.67  ? 718  ALA A O   1 
ATOM   5435  C  CB  . ALA A 1 718 ? 198.373 141.698 140.397 1.00 84.67  ? 718  ALA A CB  1 
ATOM   5436  N  N   . PHE A 1 719 ? 195.935 141.161 138.465 1.00 85.17  ? 719  PHE A N   1 
ATOM   5437  C  CA  . PHE A 1 719 ? 195.463 140.394 137.317 1.00 85.17  ? 719  PHE A CA  1 
ATOM   5438  C  C   . PHE A 1 719 ? 194.777 141.284 136.288 1.00 85.17  ? 719  PHE A C   1 
ATOM   5439  O  O   . PHE A 1 719 ? 194.926 141.072 135.079 1.00 85.17  ? 719  PHE A O   1 
ATOM   5440  C  CB  . PHE A 1 719 ? 194.521 139.283 137.780 1.00 85.17  ? 719  PHE A CB  1 
ATOM   5441  C  CG  . PHE A 1 719 ? 195.082 138.434 138.884 1.00 85.17  ? 719  PHE A CG  1 
ATOM   5442  C  CD1 . PHE A 1 719 ? 196.378 137.950 138.813 1.00 85.17  ? 719  PHE A CD1 1 
ATOM   5443  C  CD2 . PHE A 1 719 ? 194.313 138.115 139.990 1.00 85.17  ? 719  PHE A CD2 1 
ATOM   5444  C  CE1 . PHE A 1 719 ? 196.897 137.166 139.826 1.00 85.17  ? 719  PHE A CE1 1 
ATOM   5445  C  CE2 . PHE A 1 719 ? 194.826 137.332 141.007 1.00 85.17  ? 719  PHE A CE2 1 
ATOM   5446  C  CZ  . PHE A 1 719 ? 196.120 136.857 140.924 1.00 85.17  ? 719  PHE A CZ  1 
ATOM   5447  N  N   . LEU A 1 720 ? 194.022 142.280 136.743 1.00 86.03  ? 720  LEU A N   1 
ATOM   5448  C  CA  . LEU A 1 720 ? 193.288 143.131 135.824 1.00 86.03  ? 720  LEU A CA  1 
ATOM   5449  C  C   . LEU A 1 720 ? 194.244 144.023 135.032 1.00 86.03  ? 720  LEU A C   1 
ATOM   5450  O  O   . LEU A 1 720 ? 195.276 144.458 135.551 1.00 86.03  ? 720  LEU A O   1 
ATOM   5451  C  CB  . LEU A 1 720 ? 192.284 143.995 136.583 1.00 86.03  ? 720  LEU A CB  1 
ATOM   5452  C  CG  . LEU A 1 720 ? 191.169 143.244 137.311 1.00 86.03  ? 720  LEU A CG  1 
ATOM   5453  C  CD1 . LEU A 1 720 ? 190.319 144.204 138.127 1.00 86.03  ? 720  LEU A CD1 1 
ATOM   5454  C  CD2 . LEU A 1 720 ? 190.311 142.467 136.326 1.00 86.03  ? 720  LEU A CD2 1 
ATOM   5455  N  N   . PRO A 1 721 ? 193.924 144.308 133.771 1.00 87.98  ? 721  PRO A N   1 
ATOM   5456  C  CA  . PRO A 1 721 ? 194.740 145.232 132.971 1.00 87.98  ? 721  PRO A CA  1 
ATOM   5457  C  C   . PRO A 1 721 ? 194.363 146.700 133.117 1.00 87.98  ? 721  PRO A C   1 
ATOM   5458  O  O   . PRO A 1 721 ? 194.896 147.528 132.373 1.00 87.98  ? 721  PRO A O   1 
ATOM   5459  C  CB  . PRO A 1 721 ? 194.469 144.753 131.539 1.00 87.98  ? 721  PRO A CB  1 
ATOM   5460  C  CG  . PRO A 1 721 ? 193.095 144.152 131.586 1.00 87.98  ? 721  PRO A CG  1 
ATOM   5461  C  CD  . PRO A 1 721 ? 192.773 143.790 133.015 1.00 87.98  ? 721  PRO A CD  1 
ATOM   5462  N  N   . PHE A 1 722 ? 193.469 147.033 134.042 1.00 89.50  ? 722  PHE A N   1 
ATOM   5463  C  CA  . PHE A 1 722 ? 193.078 148.414 134.288 1.00 89.50  ? 722  PHE A CA  1 
ATOM   5464  C  C   . PHE A 1 722 ? 192.644 148.527 135.741 1.00 89.50  ? 722  PHE A C   1 
ATOM   5465  O  O   . PHE A 1 722 ? 192.557 147.530 136.463 1.00 89.50  ? 722  PHE A O   1 
ATOM   5466  C  CB  . PHE A 1 722 ? 191.967 148.868 133.336 1.00 89.50  ? 722  PHE A CB  1 
ATOM   5467  C  CG  . PHE A 1 722 ? 190.834 147.893 133.213 1.00 89.50  ? 722  PHE A CG  1 
ATOM   5468  C  CD1 . PHE A 1 722 ? 190.874 146.875 132.274 1.00 89.50  ? 722  PHE A CD1 1 
ATOM   5469  C  CD2 . PHE A 1 722 ? 189.726 147.994 134.035 1.00 89.50  ? 722  PHE A CD2 1 
ATOM   5470  C  CE1 . PHE A 1 722 ? 189.831 145.977 132.160 1.00 89.50  ? 722  PHE A CE1 1 
ATOM   5471  C  CE2 . PHE A 1 722 ? 188.681 147.100 133.925 1.00 89.50  ? 722  PHE A CE2 1 
ATOM   5472  C  CZ  . PHE A 1 722 ? 188.733 146.090 132.987 1.00 89.50  ? 722  PHE A CZ  1 
ATOM   5473  N  N   . LEU A 1 723 ? 192.383 149.755 136.164 1.00 85.23  ? 723  LEU A N   1 
ATOM   5474  C  CA  . LEU A 1 723 ? 191.952 149.990 137.536 1.00 85.23  ? 723  LEU A CA  1 
ATOM   5475  C  C   . LEU A 1 723 ? 190.596 149.334 137.769 1.00 85.23  ? 723  LEU A C   1 
ATOM   5476  O  O   . LEU A 1 723 ? 189.683 149.504 136.952 1.00 85.23  ? 723  LEU A O   1 
ATOM   5477  C  CB  . LEU A 1 723 ? 191.874 151.487 137.822 1.00 85.23  ? 723  LEU A CB  1 
ATOM   5478  C  CG  . LEU A 1 723 ? 193.127 152.301 137.496 1.00 85.23  ? 723  LEU A CG  1 
ATOM   5479  C  CD1 . LEU A 1 723 ? 192.902 153.771 137.805 1.00 85.23  ? 723  LEU A CD1 1 
ATOM   5480  C  CD2 . LEU A 1 723 ? 194.331 151.767 138.255 1.00 85.23  ? 723  LEU A CD2 1 
ATOM   5481  N  N   . PRO A 1 724 ? 190.427 148.572 138.853 1.00 80.19  ? 724  PRO A N   1 
ATOM   5482  C  CA  . PRO A 1 724 ? 189.118 147.950 139.112 1.00 80.19  ? 724  PRO A CA  1 
ATOM   5483  C  C   . PRO A 1 724 ? 187.995 148.961 139.235 1.00 80.19  ? 724  PRO A C   1 
ATOM   5484  O  O   . PRO A 1 724 ? 186.858 148.667 138.845 1.00 80.19  ? 724  PRO A O   1 
ATOM   5485  C  CB  . PRO A 1 724 ? 189.345 147.193 140.428 1.00 80.19  ? 724  PRO A CB  1 
ATOM   5486  C  CG  . PRO A 1 724 ? 190.825 146.983 140.496 1.00 80.19  ? 724  PRO A CG  1 
ATOM   5487  C  CD  . PRO A 1 724 ? 191.430 148.197 139.862 1.00 80.19  ? 724  PRO A CD  1 
ATOM   5488  N  N   . MET A 1 725 ? 188.282 150.144 139.770 1.00 78.65  ? 725  MET A N   1 
ATOM   5489  C  CA  . MET A 1 725 ? 187.320 151.232 139.829 1.00 78.65  ? 725  MET A CA  1 
ATOM   5490  C  C   . MET A 1 725 ? 188.083 152.542 139.734 1.00 78.65  ? 725  MET A C   1 
ATOM   5491  O  O   . MET A 1 725 ? 189.188 152.660 140.270 1.00 78.65  ? 725  MET A O   1 
ATOM   5492  C  CB  . MET A 1 725 ? 186.496 151.190 141.121 1.00 78.65  ? 725  MET A CB  1 
ATOM   5493  C  CG  . MET A 1 725 ? 185.171 151.927 141.036 1.00 78.65  ? 725  MET A CG  1 
ATOM   5494  S  SD  . MET A 1 725 ? 184.471 152.289 142.658 1.00 78.65  ? 725  MET A SD  1 
ATOM   5495  C  CE  . MET A 1 725 ? 184.059 150.645 143.232 1.00 78.65  ? 725  MET A CE  1 
ATOM   5496  N  N   . LEU A 1 726 ? 187.501 153.515 139.044 1.00 74.56  ? 726  LEU A N   1 
ATOM   5497  C  CA  . LEU A 1 726 ? 188.130 154.824 138.972 1.00 74.56  ? 726  LEU A CA  1 
ATOM   5498  C  C   . LEU A 1 726 ? 188.153 155.461 140.359 1.00 74.56  ? 726  LEU A C   1 
ATOM   5499  O  O   . LEU A 1 726 ? 187.175 155.358 141.107 1.00 74.56  ? 726  LEU A O   1 
ATOM   5500  C  CB  . LEU A 1 726 ? 187.394 155.731 137.988 1.00 74.56  ? 726  LEU A CB  1 
ATOM   5501  C  CG  . LEU A 1 726 ? 187.924 155.719 136.552 1.00 74.56  ? 726  LEU A CG  1 
ATOM   5502  C  CD1 . LEU A 1 726 ? 186.957 156.419 135.610 1.00 74.56  ? 726  LEU A CD1 1 
ATOM   5503  C  CD2 . LEU A 1 726 ? 189.302 156.358 136.483 1.00 74.56  ? 726  LEU A CD2 1 
ATOM   5504  N  N   . PRO A 1 727 ? 189.256 156.111 140.735 1.00 71.07  ? 727  PRO A N   1 
ATOM   5505  C  CA  . PRO A 1 727 ? 189.328 156.713 142.076 1.00 71.07  ? 727  PRO A CA  1 
ATOM   5506  C  C   . PRO A 1 727 ? 188.253 157.752 142.324 1.00 71.07  ? 727  PRO A C   1 
ATOM   5507  O  O   . PRO A 1 727 ? 187.851 157.952 143.477 1.00 71.07  ? 727  PRO A O   1 
ATOM   5508  C  CB  . PRO A 1 727 ? 190.731 157.331 142.104 1.00 71.07  ? 727  PRO A CB  1 
ATOM   5509  C  CG  . PRO A 1 727 ? 191.498 156.588 141.055 1.00 71.07  ? 727  PRO A CG  1 
ATOM   5510  C  CD  . PRO A 1 727 ? 190.506 156.290 139.980 1.00 71.07  ? 727  PRO A CD  1 
ATOM   5511  N  N   . LEU A 1 728 ? 187.782 158.429 141.276 1.00 73.33  ? 728  LEU A N   1 
ATOM   5512  C  CA  . LEU A 1 728 ? 186.656 159.342 141.434 1.00 73.33  ? 728  LEU A CA  1 
ATOM   5513  C  C   . LEU A 1 728 ? 185.413 158.591 141.892 1.00 73.33  ? 728  LEU A C   1 
ATOM   5514  O  O   . LEU A 1 728 ? 184.674 159.063 142.766 1.00 73.33  ? 728  LEU A O   1 
ATOM   5515  C  CB  . LEU A 1 728 ? 186.406 160.074 140.115 1.00 73.33  ? 728  LEU A CB  1 
ATOM   5516  C  CG  . LEU A 1 728 ? 185.416 161.236 140.032 1.00 73.33  ? 728  LEU A CG  1 
ATOM   5517  C  CD1 . LEU A 1 728 ? 185.840 162.153 138.900 1.00 73.33  ? 728  LEU A CD1 1 
ATOM   5518  C  CD2 . LEU A 1 728 ? 183.994 160.750 139.806 1.00 73.33  ? 728  LEU A CD2 1 
ATOM   5519  N  N   . HIS A 1 729 ? 185.173 157.409 141.321 1.00 76.39  ? 729  HIS A N   1 
ATOM   5520  C  CA  . HIS A 1 729 ? 184.058 156.585 141.772 1.00 76.39  ? 729  HIS A CA  1 
ATOM   5521  C  C   . HIS A 1 729 ? 184.254 156.136 143.214 1.00 76.39  ? 729  HIS A C   1 
ATOM   5522  O  O   . HIS A 1 729 ? 183.286 156.040 143.974 1.00 76.39  ? 729  HIS A O   1 
ATOM   5523  C  CB  . HIS A 1 729 ? 183.885 155.379 140.850 1.00 76.39  ? 729  HIS A CB  1 
ATOM   5524  C  CG  . HIS A 1 729 ? 183.741 155.740 139.404 1.00 76.39  ? 729  HIS A CG  1 
ATOM   5525  N  ND1 . HIS A 1 729 ? 184.229 154.947 138.388 1.00 76.39  ? 729  HIS A ND1 1 
ATOM   5526  C  CD2 . HIS A 1 729 ? 183.166 156.808 138.804 1.00 76.39  ? 729  HIS A CD2 1 
ATOM   5527  C  CE1 . HIS A 1 729 ? 183.959 155.511 137.224 1.00 76.39  ? 729  HIS A CE1 1 
ATOM   5528  N  NE2 . HIS A 1 729 ? 183.315 156.642 137.449 1.00 76.39  ? 729  HIS A NE2 1 
ATOM   5529  N  N   . LEU A 1 730 ? 185.497 155.853 143.610 1.00 71.90  ? 730  LEU A N   1 
ATOM   5530  C  CA  . LEU A 1 730 ? 185.762 155.486 144.998 1.00 71.90  ? 730  LEU A CA  1 
ATOM   5531  C  C   . LEU A 1 730 ? 185.473 156.644 145.945 1.00 71.90  ? 730  LEU A C   1 
ATOM   5532  O  O   . LEU A 1 730 ? 184.931 156.439 147.036 1.00 71.90  ? 730  LEU A O   1 
ATOM   5533  C  CB  . LEU A 1 730 ? 187.207 155.019 145.152 1.00 71.90  ? 730  LEU A CB  1 
ATOM   5534  C  CG  . LEU A 1 730 ? 187.500 153.632 144.588 1.00 71.90  ? 730  LEU A CG  1 
ATOM   5535  C  CD1 . LEU A 1 730 ? 188.914 153.591 144.065 1.00 71.90  ? 730  LEU A CD1 1 
ATOM   5536  C  CD2 . LEU A 1 730 ? 187.287 152.565 145.646 1.00 71.90  ? 730  LEU A CD2 1 
ATOM   5537  N  N   . LEU A 1 731 ? 185.843 157.864 145.554 1.00 69.77  ? 731  LEU A N   1 
ATOM   5538  C  CA  . LEU A 1 731 ? 185.525 159.028 146.374 1.00 69.77  ? 731  LEU A CA  1 
ATOM   5539  C  C   . LEU A 1 731 ? 184.018 159.230 146.472 1.00 69.77  ? 731  LEU A C   1 
ATOM   5540  O  O   . LEU A 1 731 ? 183.496 159.566 147.543 1.00 69.77  ? 731  LEU A O   1 
ATOM   5541  C  CB  . LEU A 1 731 ? 186.201 160.276 145.807 1.00 69.77  ? 731  LEU A CB  1 
ATOM   5542  C  CG  . LEU A 1 731 ? 187.730 160.274 145.778 1.00 69.77  ? 731  LEU A CG  1 
ATOM   5543  C  CD1 . LEU A 1 731 ? 188.259 161.681 145.555 1.00 69.77  ? 731  LEU A CD1 1 
ATOM   5544  C  CD2 . LEU A 1 731 ? 188.293 159.686 147.061 1.00 69.77  ? 731  LEU A CD2 1 
ATOM   5545  N  N   . ILE A 1 732 ? 183.304 159.030 145.362 1.00 71.44  ? 732  ILE A N   1 
ATOM   5546  C  CA  . ILE A 1 732 ? 181.846 159.114 145.392 1.00 71.44  ? 732  ILE A CA  1 
ATOM   5547  C  C   . ILE A 1 732 ? 181.276 158.077 146.351 1.00 71.44  ? 732  ILE A C   1 
ATOM   5548  O  O   . ILE A 1 732 ? 180.379 158.371 147.153 1.00 71.44  ? 732  ILE A O   1 
ATOM   5549  C  CB  . ILE A 1 732 ? 181.274 158.945 143.972 1.00 71.44  ? 732  ILE A CB  1 
ATOM   5550  C  CG1 . ILE A 1 732 ? 181.544 160.192 143.133 1.00 71.44  ? 732  ILE A CG1 1 
ATOM   5551  C  CG2 . ILE A 1 732 ? 179.783 158.652 144.025 1.00 71.44  ? 732  ILE A CG2 1 
ATOM   5552  C  CD1 . ILE A 1 732 ? 180.945 160.131 141.747 1.00 71.44  ? 732  ILE A CD1 1 
ATOM   5553  N  N   . GLN A 1 733 ? 181.792 156.848 146.282 1.00 67.44  ? 733  GLN A N   1 
ATOM   5554  C  CA  . GLN A 1 733 ? 181.341 155.785 147.172 1.00 67.44  ? 733  GLN A CA  1 
ATOM   5555  C  C   . GLN A 1 733 ? 181.583 156.144 148.630 1.00 67.44  ? 733  GLN A C   1 
ATOM   5556  O  O   . GLN A 1 733 ? 180.701 155.959 149.475 1.00 67.44  ? 733  GLN A O   1 
ATOM   5557  C  CB  . GLN A 1 733 ? 182.056 154.481 146.817 1.00 67.44  ? 733  GLN A CB  1 
ATOM   5558  C  CG  . GLN A 1 733 ? 181.755 153.323 147.750 1.00 67.44  ? 733  GLN A CG  1 
ATOM   5559  C  CD  . GLN A 1 733 ? 182.475 152.053 147.344 1.00 67.44  ? 733  GLN A CD  1 
ATOM   5560  O  OE1 . GLN A 1 733 ? 183.141 152.007 146.310 1.00 67.44  ? 733  GLN A OE1 1 
ATOM   5561  N  NE2 . GLN A 1 733 ? 182.362 151.020 148.169 1.00 67.44  ? 733  GLN A NE2 1 
ATOM   5562  N  N   . ASN A 1 734 ? 182.772 156.661 148.943 1.00 66.30  ? 734  ASN A N   1 
ATOM   5563  C  CA  . ASN A 1 734 ? 183.089 157.025 150.321 1.00 66.30  ? 734  ASN A CA  1 
ATOM   5564  C  C   . ASN A 1 734 ? 182.178 158.141 150.817 1.00 66.30  ? 734  ASN A C   1 
ATOM   5565  O  O   . ASN A 1 734 ? 181.667 158.085 151.943 1.00 66.30  ? 734  ASN A O   1 
ATOM   5566  C  CB  . ASN A 1 734 ? 184.557 157.435 150.431 1.00 66.30  ? 734  ASN A CB  1 
ATOM   5567  C  CG  . ASN A 1 734 ? 185.504 156.276 150.193 1.00 66.30  ? 734  ASN A CG  1 
ATOM   5568  O  OD1 . ASN A 1 734 ? 185.076 155.156 149.916 1.00 66.30  ? 734  ASN A OD1 1 
ATOM   5569  N  ND2 . ASN A 1 734 ? 186.800 156.540 150.300 1.00 66.30  ? 734  ASN A ND2 1 
ATOM   5570  N  N   . LEU A 1 735 ? 181.955 159.162 149.986 1.00 64.00  ? 735  LEU A N   1 
ATOM   5571  C  CA  . LEU A 1 735 ? 181.098 160.272 150.387 1.00 64.00  ? 735  LEU A CA  1 
ATOM   5572  C  C   . LEU A 1 735 ? 179.670 159.802 150.642 1.00 64.00  ? 735  LEU A C   1 
ATOM   5573  O  O   . LEU A 1 735 ? 179.059 160.148 151.661 1.00 64.00  ? 735  LEU A O   1 
ATOM   5574  C  CB  . LEU A 1 735 ? 181.121 161.360 149.314 1.00 64.00  ? 735  LEU A CB  1 
ATOM   5575  C  CG  . LEU A 1 735 ? 180.034 162.431 149.420 1.00 64.00  ? 735  LEU A CG  1 
ATOM   5576  C  CD1 . LEU A 1 735 ? 180.254 163.300 150.649 1.00 64.00  ? 735  LEU A CD1 1 
ATOM   5577  C  CD2 . LEU A 1 735 ? 179.983 163.276 148.159 1.00 64.00  ? 735  LEU A CD2 1 
ATOM   5578  N  N   . LEU A 1 736 ? 179.123 159.002 149.725 1.00 67.27  ? 736  LEU A N   1 
ATOM   5579  C  CA  . LEU A 1 736 ? 177.751 158.529 149.882 1.00 67.27  ? 736  LEU A CA  1 
ATOM   5580  C  C   . LEU A 1 736 ? 177.622 157.593 151.079 1.00 67.27  ? 736  LEU A C   1 
ATOM   5581  O  O   . LEU A 1 736 ? 176.624 157.636 151.808 1.00 67.27  ? 736  LEU A O   1 
ATOM   5582  C  CB  . LEU A 1 736 ? 177.279 157.849 148.597 1.00 67.27  ? 736  LEU A CB  1 
ATOM   5583  C  CG  . LEU A 1 736 ? 177.192 158.785 147.389 1.00 67.27  ? 736  LEU A CG  1 
ATOM   5584  C  CD1 . LEU A 1 736 ? 176.520 158.105 146.210 1.00 67.27  ? 736  LEU A CD1 1 
ATOM   5585  C  CD2 . LEU A 1 736 ? 176.456 160.064 147.758 1.00 67.27  ? 736  LEU A CD2 1 
ATOM   5586  N  N   . TYR A 1 737 ? 178.625 156.740 151.302 1.00 61.55  ? 737  TYR A N   1 
ATOM   5587  C  CA  . TYR A 1 737 ? 178.593 155.858 152.461 1.00 61.55  ? 737  TYR A CA  1 
ATOM   5588  C  C   . TYR A 1 737 ? 178.642 156.652 153.758 1.00 61.55  ? 737  TYR A C   1 
ATOM   5589  O  O   . TYR A 1 737 ? 177.948 156.319 154.723 1.00 61.55  ? 737  TYR A O   1 
ATOM   5590  C  CB  . TYR A 1 737 ? 179.748 154.860 152.399 1.00 61.55  ? 737  TYR A CB  1 
ATOM   5591  C  CG  . TYR A 1 737 ? 179.838 153.981 153.622 1.00 61.55  ? 737  TYR A CG  1 
ATOM   5592  C  CD1 . TYR A 1 737 ? 178.814 153.099 153.941 1.00 61.55  ? 737  TYR A CD1 1 
ATOM   5593  C  CD2 . TYR A 1 737 ? 180.940 154.037 154.462 1.00 61.55  ? 737  TYR A CD2 1 
ATOM   5594  C  CE1 . TYR A 1 737 ? 178.888 152.295 155.060 1.00 61.55  ? 737  TYR A CE1 1 
ATOM   5595  C  CE2 . TYR A 1 737 ? 181.022 153.237 155.584 1.00 61.55  ? 737  TYR A CE2 1 
ATOM   5596  C  CZ  . TYR A 1 737 ? 179.994 152.368 155.878 1.00 61.55  ? 737  TYR A CZ  1 
ATOM   5597  O  OH  . TYR A 1 737 ? 180.071 151.568 156.995 1.00 61.55  ? 737  TYR A OH  1 
ATOM   5598  N  N   . ASP A 1 738 ? 179.459 157.707 153.805 1.00 62.46  ? 738  ASP A N   1 
ATOM   5599  C  CA  . ASP A 1 738 ? 179.503 158.551 154.996 1.00 62.46  ? 738  ASP A CA  1 
ATOM   5600  C  C   . ASP A 1 738 ? 178.166 159.248 155.220 1.00 62.46  ? 738  ASP A C   1 
ATOM   5601  O  O   . ASP A 1 738 ? 177.688 159.354 156.357 1.00 62.46  ? 738  ASP A O   1 
ATOM   5602  C  CB  . ASP A 1 738 ? 180.634 159.572 154.871 1.00 62.46  ? 738  ASP A CB  1 
ATOM   5603  C  CG  . ASP A 1 738 ? 182.003 158.945 155.043 1.00 62.46  ? 738  ASP A CG  1 
ATOM   5604  O  OD1 . ASP A 1 738 ? 182.073 157.728 155.313 1.00 62.46  ? 738  ASP A OD1 1 
ATOM   5605  O  OD2 . ASP A 1 738 ? 183.011 159.670 154.906 1.00 62.46  ? 738  ASP A OD2 1 
ATOM   5606  N  N   . VAL A 1 739 ? 177.546 159.730 154.140 1.00 60.99  ? 739  VAL A N   1 
ATOM   5607  C  CA  . VAL A 1 739 ? 176.227 160.347 154.257 1.00 60.99  ? 739  VAL A CA  1 
ATOM   5608  C  C   . VAL A 1 739 ? 175.215 159.348 154.799 1.00 60.99  ? 739  VAL A C   1 
ATOM   5609  O  O   . VAL A 1 739 ? 174.360 159.699 155.622 1.00 60.99  ? 739  VAL A O   1 
ATOM   5610  C  CB  . VAL A 1 739 ? 175.786 160.926 152.898 1.00 60.99  ? 739  VAL A CB  1 
ATOM   5611  C  CG1 . VAL A 1 739 ? 174.323 161.339 152.939 1.00 60.99  ? 739  VAL A CG1 1 
ATOM   5612  C  CG2 . VAL A 1 739 ? 176.662 162.109 152.521 1.00 60.99  ? 739  VAL A CG2 1 
ATOM   5613  N  N   . SER A 1 740 ? 175.291 158.093 154.354 1.00 60.61  ? 740  SER A N   1 
ATOM   5614  C  CA  . SER A 1 740 ? 174.420 157.055 154.900 1.00 60.61  ? 740  SER A CA  1 
ATOM   5615  C  C   . SER A 1 740 ? 174.698 156.825 156.381 1.00 60.61  ? 740  SER A C   1 
ATOM   5616  O  O   . SER A 1 740 ? 173.769 156.682 157.184 1.00 60.61  ? 740  SER A O   1 
ATOM   5617  C  CB  . SER A 1 740 ? 174.598 155.755 154.116 1.00 60.61  ? 740  SER A CB  1 
ATOM   5618  O  OG  . SER A 1 740 ? 173.698 154.760 154.570 1.00 60.61  ? 740  SER A OG  1 
ATOM   5619  N  N   . GLN A 1 741 ? 175.977 156.787 156.758 1.00 57.81  ? 741  GLN A N   1 
ATOM   5620  C  CA  . GLN A 1 741 ? 176.342 156.469 158.134 1.00 57.81  ? 741  GLN A CA  1 
ATOM   5621  C  C   . GLN A 1 741 ? 176.039 157.619 159.084 1.00 57.81  ? 741  GLN A C   1 
ATOM   5622  O  O   . GLN A 1 741 ? 176.052 157.429 160.305 1.00 57.81  ? 741  GLN A O   1 
ATOM   5623  C  CB  . GLN A 1 741 ? 177.823 156.098 158.212 1.00 57.81  ? 741  GLN A CB  1 
ATOM   5624  C  CG  . GLN A 1 741 ? 178.194 154.849 157.439 1.00 57.81  ? 741  GLN A CG  1 
ATOM   5625  C  CD  . GLN A 1 741 ? 177.663 153.588 158.082 1.00 57.81  ? 741  GLN A CD  1 
ATOM   5626  O  OE1 . GLN A 1 741 ? 176.699 152.993 157.604 1.00 57.81  ? 741  GLN A OE1 1 
ATOM   5627  N  NE2 . GLN A 1 741 ? 178.293 153.171 159.173 1.00 57.81  ? 741  GLN A NE2 1 
ATOM   5628  N  N   . VAL A 1 742 ? 175.789 158.815 158.549 1.00 55.00  ? 742  VAL A N   1 
ATOM   5629  C  CA  . VAL A 1 742 ? 175.428 159.980 159.357 1.00 55.00  ? 742  VAL A CA  1 
ATOM   5630  C  C   . VAL A 1 742 ? 174.354 159.635 160.387 1.00 55.00  ? 742  VAL A C   1 
ATOM   5631  O  O   . VAL A 1 742 ? 174.372 160.148 161.512 1.00 55.00  ? 742  VAL A O   1 
ATOM   5632  C  CB  . VAL A 1 742 ? 174.967 161.145 158.460 1.00 55.00  ? 742  VAL A CB  1 
ATOM   5633  C  CG1 . VAL A 1 742 ? 174.297 162.234 159.282 1.00 55.00  ? 742  VAL A CG1 1 
ATOM   5634  C  CG2 . VAL A 1 742 ? 176.146 161.723 157.703 1.00 55.00  ? 742  VAL A CG2 1 
ATOM   5635  N  N   . ALA A 1 743 ? 173.430 158.747 160.026 1.00 55.90  ? 743  ALA A N   1 
ATOM   5636  C  CA  . ALA A 1 743 ? 172.305 158.400 160.886 1.00 55.90  ? 743  ALA A CA  1 
ATOM   5637  C  C   . ALA A 1 743 ? 172.638 157.347 161.936 1.00 55.90  ? 743  ALA A C   1 
ATOM   5638  O  O   . ALA A 1 743 ? 171.771 157.014 162.749 1.00 55.90  ? 743  ALA A O   1 
ATOM   5639  C  CB  . ALA A 1 743 ? 171.124 157.916 160.038 1.00 55.90  ? 743  ALA A CB  1 
ATOM   5640  N  N   . ILE A 1 744 ? 173.860 156.804 161.933 1.00 51.24  ? 744  ILE A N   1 
ATOM   5641  C  CA  . ILE A 1 744 ? 174.224 155.793 162.933 1.00 51.24  ? 744  ILE A CA  1 
ATOM   5642  C  C   . ILE A 1 744 ? 174.128 156.323 164.356 1.00 51.24  ? 744  ILE A C   1 
ATOM   5643  O  O   . ILE A 1 744 ? 173.635 155.593 165.229 1.00 51.24  ? 744  ILE A O   1 
ATOM   5644  C  CB  . ILE A 1 744 ? 175.596 155.190 162.602 1.00 51.24  ? 744  ILE A CB  1 
ATOM   5645  C  CG1 . ILE A 1 744 ? 175.529 154.368 161.317 1.00 51.24  ? 744  ILE A CG1 1 
ATOM   5646  C  CG2 . ILE A 1 744 ? 176.091 154.325 163.749 1.00 51.24  ? 744  ILE A CG2 1 
ATOM   5647  C  CD1 . ILE A 1 744 ? 174.816 153.049 161.482 1.00 51.24  ? 744  ILE A CD1 1 
ATOM   5648  N  N   . PRO A 1 745 ? 174.582 157.556 164.685 1.00 49.09  ? 745  PRO A N   1 
ATOM   5649  C  CA  . PRO A 1 745 ? 174.394 158.065 166.054 1.00 49.09  ? 745  PRO A CA  1 
ATOM   5650  C  C   . PRO A 1 745 ? 172.967 157.953 166.577 1.00 49.09  ? 745  PRO A C   1 
ATOM   5651  O  O   . PRO A 1 745 ? 172.745 158.001 167.791 1.00 49.09  ? 745  PRO A O   1 
ATOM   5652  C  CB  . PRO A 1 745 ? 174.818 159.535 165.945 1.00 49.09  ? 745  PRO A CB  1 
ATOM   5653  C  CG  . PRO A 1 745 ? 175.703 159.614 164.757 1.00 49.09  ? 745  PRO A CG  1 
ATOM   5654  C  CD  . PRO A 1 745 ? 175.551 158.373 163.931 1.00 49.09  ? 745  PRO A CD  1 
ATOM   5655  N  N   . PHE A 1 746 ? 171.996 157.807 165.677 1.00 51.31  ? 746  PHE A N   1 
ATOM   5656  C  CA  . PHE A 1 746 ? 170.596 157.658 166.045 1.00 51.31  ? 746  PHE A CA  1 
ATOM   5657  C  C   . PHE A 1 746 ? 170.142 156.202 166.047 1.00 51.31  ? 746  PHE A C   1 
ATOM   5658  O  O   . PHE A 1 746 ? 168.938 155.941 166.133 1.00 51.31  ? 746  PHE A O   1 
ATOM   5659  C  CB  . PHE A 1 746 ? 169.710 158.476 165.101 1.00 51.31  ? 746  PHE A CB  1 
ATOM   5660  C  CG  . PHE A 1 746 ? 170.053 159.941 165.056 1.00 51.31  ? 746  PHE A CG  1 
ATOM   5661  C  CD1 . PHE A 1 746 ? 171.086 160.402 164.257 1.00 51.31  ? 746  PHE A CD1 1 
ATOM   5662  C  CD2 . PHE A 1 746 ? 169.341 160.856 165.812 1.00 51.31  ? 746  PHE A CD2 1 
ATOM   5663  C  CE1 . PHE A 1 746 ? 171.403 161.746 164.215 1.00 51.31  ? 746  PHE A CE1 1 
ATOM   5664  C  CE2 . PHE A 1 746 ? 169.653 162.202 165.772 1.00 51.31  ? 746  PHE A CE2 1 
ATOM   5665  C  CZ  . PHE A 1 746 ? 170.686 162.647 164.973 1.00 51.31  ? 746  PHE A CZ  1 
ATOM   5666  N  N   . ASP A 1 747 ? 171.073 155.255 165.962 1.00 57.20  ? 747  ASP A N   1 
ATOM   5667  C  CA  . ASP A 1 747 ? 170.730 153.842 165.888 1.00 57.20  ? 747  ASP A CA  1 
ATOM   5668  C  C   . ASP A 1 747 ? 170.186 153.342 167.226 1.00 57.20  ? 747  ASP A C   1 
ATOM   5669  O  O   . ASP A 1 747 ? 170.287 154.001 168.264 1.00 57.20  ? 747  ASP A O   1 
ATOM   5670  C  CB  . ASP A 1 747 ? 171.951 153.016 165.486 1.00 57.20  ? 747  ASP A CB  1 
ATOM   5671  C  CG  . ASP A 1 747 ? 171.580 151.691 164.852 1.00 57.20  ? 747  ASP A CG  1 
ATOM   5672  O  OD1 . ASP A 1 747 ? 170.444 151.221 165.070 1.00 57.20  ? 747  ASP A OD1 1 
ATOM   5673  O  OD2 . ASP A 1 747 ? 172.433 151.113 164.146 1.00 57.20  ? 747  ASP A OD2 1 
ATOM   5674  N  N   . ASN A 1 748 ? 169.597 152.151 167.184 1.00 63.10  ? 748  ASN A N   1 
ATOM   5675  C  CA  . ASN A 1 748 ? 169.146 151.461 168.382 1.00 63.10  ? 748  ASN A CA  1 
ATOM   5676  C  C   . ASN A 1 748 ? 170.197 150.454 168.830 1.00 63.10  ? 748  ASN A C   1 
ATOM   5677  O  O   . ASN A 1 748 ? 170.911 149.866 168.014 1.00 63.10  ? 748  ASN A O   1 
ATOM   5678  C  CB  . ASN A 1 748 ? 167.814 150.749 168.135 1.00 63.10  ? 748  ASN A CB  1 
ATOM   5679  C  CG  . ASN A 1 748 ? 166.673 151.715 167.889 1.00 63.10  ? 748  ASN A CG  1 
ATOM   5680  O  OD1 . ASN A 1 748 ? 166.580 152.761 168.532 1.00 63.10  ? 748  ASN A OD1 1 
ATOM   5681  N  ND2 . ASN A 1 748 ? 165.793 151.367 166.957 1.00 63.10  ? 748  ASN A ND2 1 
ATOM   5682  N  N   . VAL A 1 749 ? 170.285 150.260 170.143 1.00 61.77  ? 749  VAL A N   1 
ATOM   5683  C  CA  . VAL A 1 749 ? 171.277 149.384 170.752 1.00 61.77  ? 749  VAL A CA  1 
ATOM   5684  C  C   . VAL A 1 749 ? 170.548 148.291 171.519 1.00 61.77  ? 749  VAL A C   1 
ATOM   5685  O  O   . VAL A 1 749 ? 169.620 148.577 172.286 1.00 61.77  ? 749  VAL A O   1 
ATOM   5686  C  CB  . VAL A 1 749 ? 172.229 150.161 171.680 1.00 61.77  ? 749  VAL A CB  1 
ATOM   5687  C  CG1 . VAL A 1 749 ? 173.312 149.241 172.219 1.00 61.77  ? 749  VAL A CG1 1 
ATOM   5688  C  CG2 . VAL A 1 749 ? 172.840 151.341 170.944 1.00 61.77  ? 749  VAL A CG2 1 
ATOM   5689  N  N   . ASP A 1 750 ? 170.962 147.044 171.306 1.00 69.95  ? 750  ASP A N   1 
ATOM   5690  C  CA  . ASP A 1 750 ? 170.355 145.923 172.009 1.00 69.95  ? 750  ASP A CA  1 
ATOM   5691  C  C   . ASP A 1 750 ? 170.608 146.033 173.507 1.00 69.95  ? 750  ASP A C   1 
ATOM   5692  O  O   . ASP A 1 750 ? 171.646 146.537 173.944 1.00 69.95  ? 750  ASP A O   1 
ATOM   5693  C  CB  . ASP A 1 750 ? 170.911 144.600 171.484 1.00 69.95  ? 750  ASP A CB  1 
ATOM   5694  C  CG  . ASP A 1 750 ? 170.828 144.489 169.978 1.00 69.95  ? 750  ASP A CG  1 
ATOM   5695  O  OD1 . ASP A 1 750 ? 169.890 145.062 169.386 1.00 69.95  ? 750  ASP A OD1 1 
ATOM   5696  O  OD2 . ASP A 1 750 ? 171.703 143.824 169.386 1.00 69.95  ? 750  ASP A OD2 1 
ATOM   5697  N  N   . ASP A 1 751 ? 169.645 145.555 174.298 1.00 70.48  ? 751  ASP A N   1 
ATOM   5698  C  CA  . ASP A 1 751 ? 169.791 145.584 175.748 1.00 70.48  ? 751  ASP A CA  1 
ATOM   5699  C  C   . ASP A 1 751 ? 170.901 144.664 176.238 1.00 70.48  ? 751  ASP A C   1 
ATOM   5700  O  O   . ASP A 1 751 ? 171.335 144.797 177.387 1.00 70.48  ? 751  ASP A O   1 
ATOM   5701  C  CB  . ASP A 1 751 ? 168.470 145.207 176.420 1.00 70.48  ? 751  ASP A CB  1 
ATOM   5702  C  CG  . ASP A 1 751 ? 167.421 146.294 176.296 1.00 70.48  ? 751  ASP A CG  1 
ATOM   5703  O  OD1 . ASP A 1 751 ? 167.801 147.480 176.197 1.00 70.48  ? 751  ASP A OD1 1 
ATOM   5704  O  OD2 . ASP A 1 751 ? 166.217 145.963 176.300 1.00 70.48  ? 751  ASP A OD2 1 
ATOM   5705  N  N   . GLU A 1 752 ? 171.366 143.735 175.400 1.00 75.68  ? 752  GLU A N   1 
ATOM   5706  C  CA  . GLU A 1 752 ? 172.457 142.856 175.805 1.00 75.68  ? 752  GLU A CA  1 
ATOM   5707  C  C   . GLU A 1 752 ? 173.791 143.592 175.837 1.00 75.68  ? 752  GLU A C   1 
ATOM   5708  O  O   . GLU A 1 752 ? 174.643 143.291 176.680 1.00 75.68  ? 752  GLU A O   1 
ATOM   5709  C  CB  . GLU A 1 752 ? 172.535 141.654 174.865 1.00 75.68  ? 752  GLU A CB  1 
ATOM   5710  C  CG  . GLU A 1 752 ? 173.555 140.605 175.274 1.00 75.68  ? 752  GLU A CG  1 
ATOM   5711  C  CD  . GLU A 1 752 ? 173.556 139.404 174.350 1.00 75.68  ? 752  GLU A CD  1 
ATOM   5712  O  OE1 . GLU A 1 752 ? 172.783 139.407 173.369 1.00 75.68  ? 752  GLU A OE1 1 
ATOM   5713  O  OE2 . GLU A 1 752 ? 174.329 138.457 174.606 1.00 75.68  ? 752  GLU A OE2 1 
ATOM   5714  N  N   . GLN A 1 753 ? 173.989 144.555 174.934 1.00 67.37  ? 753  GLN A N   1 
ATOM   5715  C  CA  . GLN A 1 753 ? 175.249 145.289 174.898 1.00 67.37  ? 753  GLN A CA  1 
ATOM   5716  C  C   . GLN A 1 753 ? 175.351 146.298 176.034 1.00 67.37  ? 753  GLN A C   1 
ATOM   5717  O  O   . GLN A 1 753 ? 176.457 146.729 176.381 1.00 67.37  ? 753  GLN A O   1 
ATOM   5718  C  CB  . GLN A 1 753 ? 175.402 145.996 173.551 1.00 67.37  ? 753  GLN A CB  1 
ATOM   5719  C  CG  . GLN A 1 753 ? 175.297 145.071 172.351 1.00 67.37  ? 753  GLN A CG  1 
ATOM   5720  C  CD  . GLN A 1 753 ? 175.353 145.817 171.032 1.00 67.37  ? 753  GLN A CD  1 
ATOM   5721  O  OE1 . GLN A 1 753 ? 175.532 147.034 171.002 1.00 67.37  ? 753  GLN A OE1 1 
ATOM   5722  N  NE2 . GLN A 1 753 ? 175.190 145.090 169.934 1.00 67.37  ? 753  GLN A NE2 1 
ATOM   5723  N  N   . ILE A 1 754 ? 174.223 146.684 176.624 1.00 57.90  ? 754  ILE A N   1 
ATOM   5724  C  CA  . ILE A 1 754 ? 174.187 147.720 177.646 1.00 57.90  ? 754  ILE A CA  1 
ATOM   5725  C  C   . ILE A 1 754 ? 173.745 147.160 178.997 1.00 57.90  ? 754  ILE A C   1 
ATOM   5726  O  O   . ILE A 1 754 ? 173.414 147.921 179.904 1.00 57.90  ? 754  ILE A O   1 
ATOM   5727  C  CB  . ILE A 1 754 ? 173.293 148.892 177.212 1.00 57.90  ? 754  ILE A CB  1 
ATOM   5728  C  CG1 . ILE A 1 754 ? 171.875 148.394 176.930 1.00 57.90  ? 754  ILE A CG1 1 
ATOM   5729  C  CG2 . ILE A 1 754 ? 173.869 149.572 175.984 1.00 57.90  ? 754  ILE A CG2 1 
ATOM   5730  C  CD1 . ILE A 1 754 ? 170.830 149.483 176.942 1.00 57.90  ? 754  ILE A CD1 1 
ATOM   5731  N  N   . GLN A 1 755 ? 173.731 145.837 179.146 1.00 58.19  ? 755  GLN A N   1 
ATOM   5732  C  CA  . GLN A 1 755 ? 173.334 145.211 180.399 1.00 58.19  ? 755  GLN A CA  1 
ATOM   5733  C  C   . GLN A 1 755 ? 174.452 145.196 181.434 1.00 58.19  ? 755  GLN A C   1 
ATOM   5734  O  O   . GLN A 1 755 ? 174.176 144.989 182.621 1.00 58.19  ? 755  GLN A O   1 
ATOM   5735  C  CB  . GLN A 1 755 ? 172.856 143.777 180.136 1.00 58.19  ? 755  GLN A CB  1 
ATOM   5736  C  CG  . GLN A 1 755 ? 172.102 143.133 181.291 1.00 58.19  ? 755  GLN A CG  1 
ATOM   5737  C  CD  . GLN A 1 755 ? 171.646 141.722 180.973 1.00 58.19  ? 755  GLN A CD  1 
ATOM   5738  O  OE1 . GLN A 1 755 ? 171.937 141.189 179.902 1.00 58.19  ? 755  GLN A OE1 1 
ATOM   5739  N  NE2 . GLN A 1 755 ? 170.927 141.108 181.906 1.00 58.19  ? 755  GLN A NE2 1 
ATOM   5740  N  N   . LYS A 1 756 ? 175.690 145.425 181.023 1.00 49.16  ? 756  LYS A N   1 
ATOM   5741  C  CA  . LYS A 1 756 ? 176.847 145.381 181.901 1.00 49.16  ? 756  LYS A CA  1 
ATOM   5742  C  C   . LYS A 1 756 ? 177.710 146.600 181.627 1.00 49.16  ? 756  LYS A C   1 
ATOM   5743  O  O   . LYS A 1 756 ? 177.600 147.216 180.561 1.00 49.16  ? 756  LYS A O   1 
ATOM   5744  C  CB  . LYS A 1 756 ? 177.662 144.097 181.689 1.00 49.16  ? 756  LYS A CB  1 
ATOM   5745  C  CG  . LYS A 1 756 ? 176.925 142.825 182.068 1.00 49.16  ? 756  LYS A CG  1 
ATOM   5746  C  CD  . LYS A 1 756 ? 176.877 142.643 183.575 1.00 49.16  ? 756  LYS A CD  1 
ATOM   5747  C  CE  . LYS A 1 756 ? 175.494 142.213 184.033 1.00 49.16  ? 756  LYS A CE  1 
ATOM   5748  N  NZ  . LYS A 1 756 ? 175.333 142.338 185.508 1.00 49.16  ? 756  LYS A NZ  1 
ATOM   5749  N  N   . PRO A 1 757 ? 178.561 146.990 182.577 1.00 46.40  ? 757  PRO A N   1 
ATOM   5750  C  CA  . PRO A 1 757 ? 179.481 148.104 182.322 1.00 46.40  ? 757  PRO A CA  1 
ATOM   5751  C  C   . PRO A 1 757 ? 180.360 147.824 181.113 1.00 46.40  ? 757  PRO A C   1 
ATOM   5752  O  O   . PRO A 1 757 ? 180.814 146.698 180.897 1.00 46.40  ? 757  PRO A O   1 
ATOM   5753  C  CB  . PRO A 1 757 ? 180.303 148.184 183.611 1.00 46.40  ? 757  PRO A CB  1 
ATOM   5754  C  CG  . PRO A 1 757 ? 179.395 147.644 184.653 1.00 46.40  ? 757  PRO A CG  1 
ATOM   5755  C  CD  . PRO A 1 757 ? 178.625 146.542 183.979 1.00 46.40  ? 757  PRO A CD  1 
ATOM   5756  N  N   . GLN A 1 758 ? 180.596 148.865 180.321 1.00 49.53  ? 758  GLN A N   1 
ATOM   5757  C  CA  . GLN A 1 758 ? 181.329 148.732 179.072 1.00 49.53  ? 758  GLN A CA  1 
ATOM   5758  C  C   . GLN A 1 758 ? 182.829 148.832 179.308 1.00 49.53  ? 758  GLN A C   1 
ATOM   5759  O  O   . GLN A 1 758 ? 183.301 149.696 180.051 1.00 49.53  ? 758  GLN A O   1 
ATOM   5760  C  CB  . GLN A 1 758 ? 180.889 149.805 178.076 1.00 49.53  ? 758  GLN A CB  1 
ATOM   5761  C  CG  . GLN A 1 758 ? 179.430 149.713 177.671 1.00 49.53  ? 758  GLN A CG  1 
ATOM   5762  C  CD  . GLN A 1 758 ? 178.974 150.911 176.865 1.00 49.53  ? 758  GLN A CD  1 
ATOM   5763  O  OE1 . GLN A 1 758 ? 179.455 152.027 177.063 1.00 49.53  ? 758  GLN A OE1 1 
ATOM   5764  N  NE2 . GLN A 1 758 ? 178.045 150.686 175.945 1.00 49.53  ? 758  GLN A NE2 1 
ATOM   5765  N  N   . ARG A 1 759 ? 183.573 147.935 178.669 1.00 53.71  ? 759  ARG A N   1 
ATOM   5766  C  CA  . ARG A 1 759 ? 185.027 147.981 178.638 1.00 53.71  ? 759  ARG A CA  1 
ATOM   5767  C  C   . ARG A 1 759 ? 185.466 148.131 177.190 1.00 53.71  ? 759  ARG A C   1 
ATOM   5768  O  O   . ARG A 1 759 ? 185.051 147.348 176.330 1.00 53.71  ? 759  ARG A O   1 
ATOM   5769  C  CB  . ARG A 1 759 ? 185.638 146.723 179.260 1.00 53.71  ? 759  ARG A CB  1 
ATOM   5770  C  CG  . ARG A 1 759 ? 185.180 146.454 180.681 1.00 53.71  ? 759  ARG A CG  1 
ATOM   5771  C  CD  . ARG A 1 759 ? 185.670 147.531 181.634 1.00 53.71  ? 759  ARG A CD  1 
ATOM   5772  N  NE  . ARG A 1 759 ? 185.023 147.438 182.937 1.00 53.71  ? 759  ARG A NE  1 
ATOM   5773  C  CZ  . ARG A 1 759 ? 185.373 148.149 184.000 1.00 53.71  ? 759  ARG A CZ  1 
ATOM   5774  N  NH1 . ARG A 1 759 ? 186.378 149.009 183.957 1.00 53.71  ? 759  ARG A NH1 1 
ATOM   5775  N  NH2 . ARG A 1 759 ? 184.699 147.992 185.136 1.00 53.71  ? 759  ARG A NH2 1 
ATOM   5776  N  N   . TRP A 1 760 ? 186.295 149.134 176.924 1.00 52.29  ? 760  TRP A N   1 
ATOM   5777  C  CA  . TRP A 1 760 ? 186.698 149.479 175.567 1.00 52.29  ? 760  TRP A CA  1 
ATOM   5778  C  C   . TRP A 1 760 ? 188.135 149.027 175.347 1.00 52.29  ? 760  TRP A C   1 
ATOM   5779  O  O   . TRP A 1 760 ? 189.043 149.457 176.067 1.00 52.29  ? 760  TRP A O   1 
ATOM   5780  C  CB  . TRP A 1 760 ? 186.555 150.982 175.326 1.00 52.29  ? 760  TRP A CB  1 
ATOM   5781  C  CG  . TRP A 1 760 ? 187.066 151.442 173.995 1.00 52.29  ? 760  TRP A CG  1 
ATOM   5782  C  CD1 . TRP A 1 760 ? 187.120 150.717 172.839 1.00 52.29  ? 760  TRP A CD1 1 
ATOM   5783  C  CD2 . TRP A 1 760 ? 187.576 152.741 173.677 1.00 52.29  ? 760  TRP A CD2 1 
ATOM   5784  N  NE1 . TRP A 1 760 ? 187.643 151.482 171.825 1.00 52.29  ? 760  TRP A NE1 1 
ATOM   5785  C  CE2 . TRP A 1 760 ? 187.929 152.729 172.314 1.00 52.29  ? 760  TRP A CE2 1 
ATOM   5786  C  CE3 . TRP A 1 760 ? 187.771 153.913 174.413 1.00 52.29  ? 760  TRP A CE3 1 
ATOM   5787  C  CZ2 . TRP A 1 760 ? 188.467 153.841 171.673 1.00 52.29  ? 760  TRP A CZ2 1 
ATOM   5788  C  CZ3 . TRP A 1 760 ? 188.305 155.015 173.775 1.00 52.29  ? 760  TRP A CZ3 1 
ATOM   5789  C  CH2 . TRP A 1 760 ? 188.646 154.972 172.419 1.00 52.29  ? 760  TRP A CH2 1 
ATOM   5790  N  N   . ASN A 1 761 ? 188.333 148.166 174.357 1.00 54.57  ? 761  ASN A N   1 
ATOM   5791  C  CA  . ASN A 1 761 ? 189.661 147.672 173.996 1.00 54.57  ? 761  ASN A CA  1 
ATOM   5792  C  C   . ASN A 1 761 ? 189.996 148.124 172.584 1.00 54.57  ? 761  ASN A C   1 
ATOM   5793  O  O   . ASN A 1 761 ? 189.410 147.603 171.616 1.00 54.57  ? 761  ASN A O   1 
ATOM   5794  C  CB  . ASN A 1 761 ? 189.722 146.148 174.100 1.00 54.57  ? 761  ASN A CB  1 
ATOM   5795  C  CG  . ASN A 1 761 ? 191.138 145.633 174.257 1.00 54.57  ? 761  ASN A CG  1 
ATOM   5796  O  OD1 . ASN A 1 761 ? 192.085 146.411 174.369 1.00 54.57  ? 761  ASN A OD1 1 
ATOM   5797  N  ND2 . ASN A 1 761 ? 191.289 144.314 174.270 1.00 54.57  ? 761  ASN A ND2 1 
ATOM   5798  N  N   . PRO A 1 762 ? 190.907 149.083 172.409 1.00 53.59  ? 762  PRO A N   1 
ATOM   5799  C  CA  . PRO A 1 762 ? 191.235 149.549 171.051 1.00 53.59  ? 762  PRO A CA  1 
ATOM   5800  C  C   . PRO A 1 762 ? 191.779 148.461 170.144 1.00 53.59  ? 762  PRO A C   1 
ATOM   5801  O  O   . PRO A 1 762 ? 191.622 148.563 168.921 1.00 53.59  ? 762  PRO A O   1 
ATOM   5802  C  CB  . PRO A 1 762 ? 192.282 150.642 171.302 1.00 53.59  ? 762  PRO A CB  1 
ATOM   5803  C  CG  . PRO A 1 762 ? 192.024 151.095 172.704 1.00 53.59  ? 762  PRO A CG  1 
ATOM   5804  C  CD  . PRO A 1 762 ? 191.614 149.857 173.443 1.00 53.59  ? 762  PRO A CD  1 
ATOM   5805  N  N   . ALA A 1 763 ? 192.416 147.428 170.697 1.00 58.23  ? 763  ALA A N   1 
ATOM   5806  C  CA  . ALA A 1 763 ? 192.940 146.349 169.868 1.00 58.23  ? 763  ALA A CA  1 
ATOM   5807  C  C   . ALA A 1 763 ? 191.836 145.487 169.269 1.00 58.23  ? 763  ALA A C   1 
ATOM   5808  O  O   . ALA A 1 763 ? 192.096 144.750 168.313 1.00 58.23  ? 763  ALA A O   1 
ATOM   5809  C  CB  . ALA A 1 763 ? 193.896 145.476 170.680 1.00 58.23  ? 763  ALA A CB  1 
ATOM   5810  N  N   . ASP A 1 764 ? 190.617 145.559 169.809 1.00 62.31  ? 764  ASP A N   1 
ATOM   5811  C  CA  . ASP A 1 764 ? 189.516 144.776 169.259 1.00 62.31  ? 764  ASP A CA  1 
ATOM   5812  C  C   . ASP A 1 764 ? 189.126 145.253 167.866 1.00 62.31  ? 764  ASP A C   1 
ATOM   5813  O  O   . ASP A 1 764 ? 188.613 144.465 167.063 1.00 62.31  ? 764  ASP A O   1 
ATOM   5814  C  CB  . ASP A 1 764 ? 188.310 144.837 170.197 1.00 62.31  ? 764  ASP A CB  1 
ATOM   5815  C  CG  . ASP A 1 764 ? 187.439 143.599 170.112 1.00 62.31  ? 764  ASP A CG  1 
ATOM   5816  O  OD1 . ASP A 1 764 ? 187.546 142.860 169.111 1.00 62.31  ? 764  ASP A OD1 1 
ATOM   5817  O  OD2 . ASP A 1 764 ? 186.647 143.363 171.049 1.00 62.31  ? 764  ASP A OD2 1 
ATOM   5818  N  N   . LEU A 1 765 ? 189.354 146.534 167.565 1.00 54.46  ? 765  LEU A N   1 
ATOM   5819  C  CA  . LEU A 1 765 ? 189.026 147.053 166.241 1.00 54.46  ? 765  LEU A CA  1 
ATOM   5820  C  C   . LEU A 1 765 ? 189.860 146.375 165.162 1.00 54.46  ? 765  LEU A C   1 
ATOM   5821  O  O   . LEU A 1 765 ? 189.354 146.072 164.075 1.00 54.46  ? 765  LEU A O   1 
ATOM   5822  C  CB  . LEU A 1 765 ? 189.229 148.567 166.205 1.00 54.46  ? 765  LEU A CB  1 
ATOM   5823  C  CG  . LEU A 1 765 ? 189.103 149.224 164.830 1.00 54.46  ? 765  LEU A CG  1 
ATOM   5824  C  CD1 . LEU A 1 765 ? 187.684 149.094 164.307 1.00 54.46  ? 765  LEU A CD1 1 
ATOM   5825  C  CD2 . LEU A 1 765 ? 189.520 150.681 164.891 1.00 54.46  ? 765  LEU A CD2 1 
ATOM   5826  N  N   . GLY A 1 766 ? 191.143 146.136 165.440 1.00 60.08  ? 766  GLY A N   1 
ATOM   5827  C  CA  . GLY A 1 766 ? 191.977 145.441 164.474 1.00 60.08  ? 766  GLY A CA  1 
ATOM   5828  C  C   . GLY A 1 766 ? 191.500 144.028 164.204 1.00 60.08  ? 766  GLY A C   1 
ATOM   5829  O  O   . GLY A 1 766 ? 191.465 143.583 163.053 1.00 60.08  ? 766  GLY A O   1 
ATOM   5830  N  N   . ARG A 1 767 ? 191.124 143.303 165.260 1.00 64.82  ? 767  ARG A N   1 
ATOM   5831  C  CA  . ARG A 1 767 ? 190.589 141.958 165.078 1.00 64.82  ? 767  ARG A CA  1 
ATOM   5832  C  C   . ARG A 1 767 ? 189.292 141.989 164.282 1.00 64.82  ? 767  ARG A C   1 
ATOM   5833  O  O   . ARG A 1 767 ? 189.076 141.149 163.400 1.00 64.82  ? 767  ARG A O   1 
ATOM   5834  C  CB  . ARG A 1 767 ? 190.369 141.292 166.436 1.00 64.82  ? 767  ARG A CB  1 
ATOM   5835  C  CG  . ARG A 1 767 ? 191.650 140.962 167.180 1.00 64.82  ? 767  ARG A CG  1 
ATOM   5836  C  CD  . ARG A 1 767 ? 191.424 139.853 168.193 1.00 64.82  ? 767  ARG A CD  1 
ATOM   5837  N  NE  . ARG A 1 767 ? 190.100 139.933 168.798 1.00 64.82  ? 767  ARG A NE  1 
ATOM   5838  C  CZ  . ARG A 1 767 ? 189.830 140.566 169.931 1.00 64.82  ? 767  ARG A CZ  1 
ATOM   5839  N  NH1 . ARG A 1 767 ? 190.773 141.193 170.613 1.00 64.82  ? 767  ARG A NH1 1 
ATOM   5840  N  NH2 . ARG A 1 767 ? 188.582 140.570 170.391 1.00 64.82  ? 767  ARG A NH2 1 
ATOM   5841  N  N   . PHE A 1 768 ? 188.418 142.956 164.574 1.00 62.78  ? 768  PHE A N   1 
ATOM   5842  C  CA  . PHE A 1 768 ? 187.168 143.076 163.830 1.00 62.78  ? 768  PHE A CA  1 
ATOM   5843  C  C   . PHE A 1 768 ? 187.431 143.340 162.353 1.00 62.78  ? 768  PHE A C   1 
ATOM   5844  O  O   . PHE A 1 768 ? 186.796 142.733 161.481 1.00 62.78  ? 768  PHE A O   1 
ATOM   5845  C  CB  . PHE A 1 768 ? 186.311 144.189 164.433 1.00 62.78  ? 768  PHE A CB  1 
ATOM   5846  C  CG  . PHE A 1 768 ? 184.884 144.183 163.965 1.00 62.78  ? 768  PHE A CG  1 
ATOM   5847  C  CD1 . PHE A 1 768 ? 184.520 144.825 162.793 1.00 62.78  ? 768  PHE A CD1 1 
ATOM   5848  C  CD2 . PHE A 1 768 ? 183.904 143.544 164.704 1.00 62.78  ? 768  PHE A CD2 1 
ATOM   5849  C  CE1 . PHE A 1 768 ? 183.207 144.823 162.364 1.00 62.78  ? 768  PHE A CE1 1 
ATOM   5850  C  CE2 . PHE A 1 768 ? 182.588 143.540 164.280 1.00 62.78  ? 768  PHE A CE2 1 
ATOM   5851  C  CZ  . PHE A 1 768 ? 182.240 144.180 163.109 1.00 62.78  ? 768  PHE A CZ  1 
ATOM   5852  N  N   . MET A 1 769 ? 188.366 144.245 162.053 1.00 63.28  ? 769  MET A N   1 
ATOM   5853  C  CA  . MET A 1 769 ? 188.697 144.543 160.664 1.00 63.28  ? 769  MET A CA  1 
ATOM   5854  C  C   . MET A 1 769 ? 189.266 143.318 159.962 1.00 63.28  ? 769  MET A C   1 
ATOM   5855  O  O   . MET A 1 769 ? 188.870 142.991 158.837 1.00 63.28  ? 769  MET A O   1 
ATOM   5856  C  CB  . MET A 1 769 ? 189.689 145.705 160.602 1.00 63.28  ? 769  MET A CB  1 
ATOM   5857  C  CG  . MET A 1 769 ? 189.109 147.049 160.999 1.00 63.28  ? 769  MET A CG  1 
ATOM   5858  S  SD  . MET A 1 769 ? 190.388 148.300 161.216 1.00 63.28  ? 769  MET A SD  1 
ATOM   5859  C  CE  . MET A 1 769 ? 191.340 148.077 159.717 1.00 63.28  ? 769  MET A CE  1 
ATOM   5860  N  N   . ILE A 1 770 ? 190.195 142.620 160.619 1.00 65.89  ? 770  ILE A N   1 
ATOM   5861  C  CA  . ILE A 1 770 ? 190.803 141.436 160.018 1.00 65.89  ? 770  ILE A CA  1 
ATOM   5862  C  C   . ILE A 1 770 ? 189.746 140.372 159.757 1.00 65.89  ? 770  ILE A C   1 
ATOM   5863  O  O   . ILE A 1 770 ? 189.787 139.667 158.742 1.00 65.89  ? 770  ILE A O   1 
ATOM   5864  C  CB  . ILE A 1 770 ? 191.938 140.909 160.917 1.00 65.89  ? 770  ILE A CB  1 
ATOM   5865  C  CG1 . ILE A 1 770 ? 193.136 141.859 160.874 1.00 65.89  ? 770  ILE A CG1 1 
ATOM   5866  C  CG2 . ILE A 1 770 ? 192.359 139.509 160.497 1.00 65.89  ? 770  ILE A CG2 1 
ATOM   5867  C  CD1 . ILE A 1 770 ? 193.733 142.027 159.495 1.00 65.89  ? 770  ILE A CD1 1 
ATOM   5868  N  N   . PHE A 1 771 ? 188.772 140.251 160.660 1.00 70.47  ? 771  PHE A N   1 
ATOM   5869  C  CA  . PHE A 1 771 ? 187.752 139.221 160.508 1.00 70.47  ? 771  PHE A CA  1 
ATOM   5870  C  C   . PHE A 1 771 ? 186.757 139.572 159.408 1.00 70.47  ? 771  PHE A C   1 
ATOM   5871  O  O   . PHE A 1 771 ? 186.312 138.689 158.666 1.00 70.47  ? 771  PHE A O   1 
ATOM   5872  C  CB  . PHE A 1 771 ? 187.032 139.009 161.839 1.00 70.47  ? 771  PHE A CB  1 
ATOM   5873  C  CG  . PHE A 1 771 ? 186.220 137.751 161.896 1.00 70.47  ? 771  PHE A CG  1 
ATOM   5874  C  CD1 . PHE A 1 771 ? 186.804 136.552 162.266 1.00 70.47  ? 771  PHE A CD1 1 
ATOM   5875  C  CD2 . PHE A 1 771 ? 184.872 137.766 161.586 1.00 70.47  ? 771  PHE A CD2 1 
ATOM   5876  C  CE1 . PHE A 1 771 ? 186.060 135.391 162.322 1.00 70.47  ? 771  PHE A CE1 1 
ATOM   5877  C  CE2 . PHE A 1 771 ? 184.124 136.610 161.640 1.00 70.47  ? 771  PHE A CE2 1 
ATOM   5878  C  CZ  . PHE A 1 771 ? 184.717 135.420 162.008 1.00 70.47  ? 771  PHE A CZ  1 
ATOM   5879  N  N   . PHE A 1 772 ? 186.390 140.848 159.283 1.00 67.67  ? 772  PHE A N   1 
ATOM   5880  C  CA  . PHE A 1 772 ? 185.308 141.240 158.389 1.00 67.67  ? 772  PHE A CA  1 
ATOM   5881  C  C   . PHE A 1 772 ? 185.776 141.874 157.082 1.00 67.67  ? 772  PHE A C   1 
ATOM   5882  O  O   . PHE A 1 772 ? 184.935 142.338 156.306 1.00 67.67  ? 772  PHE A O   1 
ATOM   5883  C  CB  . PHE A 1 772 ? 184.354 142.194 159.113 1.00 67.67  ? 772  PHE A CB  1 
ATOM   5884  C  CG  . PHE A 1 772 ? 183.341 141.496 159.973 1.00 67.67  ? 772  PHE A CG  1 
ATOM   5885  C  CD1 . PHE A 1 772 ? 182.136 141.071 159.440 1.00 67.67  ? 772  PHE A CD1 1 
ATOM   5886  C  CD2 . PHE A 1 772 ? 183.596 141.258 161.312 1.00 67.67  ? 772  PHE A CD2 1 
ATOM   5887  C  CE1 . PHE A 1 772 ? 181.202 140.425 160.228 1.00 67.67  ? 772  PHE A CE1 1 
ATOM   5888  C  CE2 . PHE A 1 772 ? 182.666 140.613 162.105 1.00 67.67  ? 772  PHE A CE2 1 
ATOM   5889  C  CZ  . PHE A 1 772 ? 181.468 140.197 161.562 1.00 67.67  ? 772  PHE A CZ  1 
ATOM   5890  N  N   . GLY A 1 773 ? 187.079 141.911 156.815 1.00 71.64  ? 773  GLY A N   1 
ATOM   5891  C  CA  . GLY A 1 773 ? 187.570 142.407 155.549 1.00 71.64  ? 773  GLY A CA  1 
ATOM   5892  C  C   . GLY A 1 773 ? 187.499 141.396 154.417 1.00 71.64  ? 773  GLY A C   1 
ATOM   5893  O  O   . GLY A 1 773 ? 186.878 141.638 153.374 1.00 71.64  ? 773  GLY A O   1 
ATOM   5894  N  N   . PRO A 1 774 ? 188.151 140.243 154.594 1.00 77.09  ? 774  PRO A N   1 
ATOM   5895  C  CA  . PRO A 1 774 ? 188.111 139.214 153.542 1.00 77.09  ? 774  PRO A CA  1 
ATOM   5896  C  C   . PRO A 1 774 ? 186.709 138.745 153.198 1.00 77.09  ? 774  PRO A C   1 
ATOM   5897  O  O   . PRO A 1 774 ? 186.499 138.248 152.085 1.00 77.09  ? 774  PRO A O   1 
ATOM   5898  C  CB  . PRO A 1 774 ? 188.954 138.079 154.136 1.00 77.09  ? 774  PRO A CB  1 
ATOM   5899  C  CG  . PRO A 1 774 ? 189.913 138.775 155.032 1.00 77.09  ? 774  PRO A CG  1 
ATOM   5900  C  CD  . PRO A 1 774 ? 189.149 139.924 155.631 1.00 77.09  ? 774  PRO A CD  1 
ATOM   5901  N  N   . ILE A 1 775 ? 185.768 138.890 154.126 1.00 74.74  ? 775  ILE A N   1 
ATOM   5902  C  CA  . ILE A 1 775 ? 184.396 138.480 153.866 1.00 74.74  ? 775  ILE A CA  1 
ATOM   5903  C  C   . ILE A 1 775 ? 183.805 139.401 152.811 1.00 74.74  ? 775  ILE A C   1 
ATOM   5904  O  O   . ILE A 1 775 ? 182.984 138.987 151.994 1.00 74.74  ? 775  ILE A O   1 
ATOM   5905  C  CB  . ILE A 1 775 ? 183.532 138.523 155.134 1.00 74.74  ? 775  ILE A CB  1 
ATOM   5906  C  CG1 . ILE A 1 775 ? 184.021 137.484 156.142 1.00 74.74  ? 775  ILE A CG1 1 
ATOM   5907  C  CG2 . ILE A 1 775 ? 182.073 138.273 154.788 1.00 74.74  ? 775  ILE A CG2 1 
ATOM   5908  C  CD1 . ILE A 1 775 ? 183.106 137.313 157.333 1.00 74.74  ? 775  ILE A CD1 1 
ATOM   5909  N  N   . SER A 1 776 ? 184.231 140.660 152.841 1.00 75.86  ? 776  SER A N   1 
ATOM   5910  C  CA  . SER A 1 776 ? 183.775 141.651 151.877 1.00 75.86  ? 776  SER A CA  1 
ATOM   5911  C  C   . SER A 1 776 ? 184.685 141.679 150.651 1.00 75.86  ? 776  SER A C   1 
ATOM   5912  O  O   . SER A 1 776 ? 184.420 142.391 149.685 1.00 75.86  ? 776  SER A O   1 
ATOM   5913  C  CB  . SER A 1 776 ? 183.716 143.033 152.523 1.00 75.86  ? 776  SER A CB  1 
ATOM   5914  O  OG  . SER A 1 776 ? 184.952 143.351 153.134 1.00 75.86  ? 776  SER A OG  1 
ATOM   5915  N  N   . SER A 1 777 ? 185.764 140.903 150.704 1.00 76.96  ? 777  SER A N   1 
ATOM   5916  C  CA  . SER A 1 777 ? 186.715 140.822 149.604 1.00 76.96  ? 777  SER A CA  1 
ATOM   5917  C  C   . SER A 1 777 ? 186.338 139.675 148.678 1.00 76.96  ? 777  SER A C   1 
ATOM   5918  O  O   . SER A 1 777 ? 186.424 139.799 147.457 1.00 76.96  ? 777  SER A O   1 
ATOM   5919  C  CB  . SER A 1 777 ? 188.131 140.613 150.135 1.00 76.96  ? 777  SER A CB  1 
ATOM   5920  O  OG  . SER A 1 777 ? 188.476 141.614 151.073 1.00 76.96  ? 777  SER A OG  1 
ATOM   5921  N  N   . ILE A 1 778 ? 185.928 138.557 149.270 1.00 79.15  ? 778  ILE A N   1 
ATOM   5922  C  CA  . ILE A 1 778 ? 185.525 137.384 148.496 1.00 79.15  ? 778  ILE A CA  1 
ATOM   5923  C  C   . ILE A 1 778 ? 184.450 137.760 147.483 1.00 79.15  ? 778  ILE A C   1 
ATOM   5924  O  O   . ILE A 1 778 ? 184.531 137.409 146.299 1.00 79.15  ? 778  ILE A O   1 
ATOM   5925  C  CB  . ILE A 1 778 ? 185.053 136.260 149.436 1.00 79.15  ? 778  ILE A CB  1 
ATOM   5926  C  CG1 . ILE A 1 778 ? 186.255 135.560 150.072 1.00 79.15  ? 778  ILE A CG1 1 
ATOM   5927  C  CG2 . ILE A 1 778 ? 184.188 135.258 148.686 1.00 79.15  ? 778  ILE A CG2 1 
ATOM   5928  C  CD1 . ILE A 1 778 ? 185.882 134.569 151.152 1.00 79.15  ? 778  ILE A CD1 1 
ATOM   5929  N  N   . PHE A 1 779 ? 183.433 138.496 147.927 1.00 79.26  ? 779  PHE A N   1 
ATOM   5930  C  CA  . PHE A 1 779 ? 182.377 138.911 147.015 1.00 79.26  ? 779  PHE A CA  1 
ATOM   5931  C  C   . PHE A 1 779 ? 182.831 139.998 146.051 1.00 79.26  ? 779  PHE A C   1 
ATOM   5932  O  O   . PHE A 1 779 ? 182.306 140.072 144.935 1.00 79.26  ? 779  PHE A O   1 
ATOM   5933  C  CB  . PHE A 1 779 ? 181.152 139.363 147.807 1.00 79.26  ? 779  PHE A CB  1 
ATOM   5934  C  CG  . PHE A 1 779 ? 180.454 138.237 148.510 1.00 79.26  ? 779  PHE A CG  1 
ATOM   5935  C  CD1 . PHE A 1 779 ? 179.429 137.544 147.888 1.00 79.26  ? 779  PHE A CD1 1 
ATOM   5936  C  CD2 . PHE A 1 779 ? 180.842 137.850 149.780 1.00 79.26  ? 779  PHE A CD2 1 
ATOM   5937  C  CE1 . PHE A 1 779 ? 178.793 136.498 148.528 1.00 79.26  ? 779  PHE A CE1 1 
ATOM   5938  C  CE2 . PHE A 1 779 ? 180.210 136.808 150.424 1.00 79.26  ? 779  PHE A CE2 1 
ATOM   5939  C  CZ  . PHE A 1 779 ? 179.187 136.127 149.797 1.00 79.26  ? 779  PHE A CZ  1 
ATOM   5940  N  N   . ASP A 1 780 ? 183.809 140.821 146.435 1.00 82.72  ? 780  ASP A N   1 
ATOM   5941  C  CA  . ASP A 1 780 ? 184.407 141.734 145.466 1.00 82.72  ? 780  ASP A CA  1 
ATOM   5942  C  C   . ASP A 1 780 ? 185.100 140.963 144.346 1.00 82.72  ? 780  ASP A C   1 
ATOM   5943  O  O   . ASP A 1 780 ? 184.980 141.318 143.168 1.00 82.72  ? 780  ASP A O   1 
ATOM   5944  C  CB  . ASP A 1 780 ? 185.388 142.673 146.166 1.00 82.72  ? 780  ASP A CB  1 
ATOM   5945  C  CG  . ASP A 1 780 ? 184.708 143.896 146.745 1.00 82.72  ? 780  ASP A CG  1 
ATOM   5946  O  OD1 . ASP A 1 780 ? 183.755 144.400 146.115 1.00 82.72  ? 780  ASP A OD1 1 
ATOM   5947  O  OD2 . ASP A 1 780 ? 185.124 144.351 147.831 1.00 82.72  ? 780  ASP A OD2 1 
ATOM   5948  N  N   . ILE A 1 781 ? 185.825 139.899 144.698 1.00 82.59  ? 781  ILE A N   1 
ATOM   5949  C  CA  . ILE A 1 781 ? 186.464 139.055 143.692 1.00 82.59  ? 781  ILE A CA  1 
ATOM   5950  C  C   . ILE A 1 781 ? 185.415 138.372 142.821 1.00 82.59  ? 781  ILE A C   1 
ATOM   5951  O  O   . ILE A 1 781 ? 185.591 138.232 141.605 1.00 82.59  ? 781  ILE A O   1 
ATOM   5952  C  CB  . ILE A 1 781 ? 187.396 138.034 144.370 1.00 82.59  ? 781  ILE A CB  1 
ATOM   5953  C  CG1 . ILE A 1 781 ? 188.615 138.739 144.967 1.00 82.59  ? 781  ILE A CG1 1 
ATOM   5954  C  CG2 . ILE A 1 781 ? 187.836 136.962 143.385 1.00 82.59  ? 781  ILE A CG2 1 
ATOM   5955  C  CD1 . ILE A 1 781 ? 189.208 138.024 146.161 1.00 82.59  ? 781  ILE A CD1 1 
ATOM   5956  N  N   . LEU A 1 782 ? 184.316 137.922 143.431 1.00 82.98  ? 782  LEU A N   1 
ATOM   5957  C  CA  . LEU A 1 782 ? 183.239 137.312 142.655 1.00 82.98  ? 782  LEU A CA  1 
ATOM   5958  C  C   . LEU A 1 782 ? 182.644 138.302 141.660 1.00 82.98  ? 782  LEU A C   1 
ATOM   5959  O  O   . LEU A 1 782 ? 182.383 137.952 140.503 1.00 82.98  ? 782  LEU A O   1 
ATOM   5960  C  CB  . LEU A 1 782 ? 182.153 136.776 143.589 1.00 82.98  ? 782  LEU A CB  1 
ATOM   5961  C  CG  . LEU A 1 782 ? 182.503 135.559 144.447 1.00 82.98  ? 782  LEU A CG  1 
ATOM   5962  C  CD1 . LEU A 1 782 ? 181.236 134.858 144.908 1.00 82.98  ? 782  LEU A CD1 1 
ATOM   5963  C  CD2 . LEU A 1 782 ? 183.399 134.597 143.684 1.00 82.98  ? 782  LEU A CD2 1 
ATOM   5964  N  N   . THR A 1 783 ? 182.420 139.545 142.094 1.00 84.33  ? 783  THR A N   1 
ATOM   5965  C  CA  . THR A 1 783 ? 181.913 140.570 141.187 1.00 84.33  ? 783  THR A CA  1 
ATOM   5966  C  C   . THR A 1 783 ? 182.915 140.865 140.076 1.00 84.33  ? 783  THR A C   1 
ATOM   5967  O  O   . THR A 1 783 ? 182.528 141.089 138.922 1.00 84.33  ? 783  THR A O   1 
ATOM   5968  C  CB  . THR A 1 783 ? 181.581 141.840 141.971 1.00 84.33  ? 783  THR A CB  1 
ATOM   5969  O  OG1 . THR A 1 783 ? 180.610 141.534 142.979 1.00 84.33  ? 783  THR A OG1 1 
ATOM   5970  C  CG2 . THR A 1 783 ? 181.017 142.907 141.049 1.00 84.33  ? 783  THR A CG2 1 
ATOM   5971  N  N   . PHE A 1 784 ? 184.208 140.872 140.408 1.00 84.55  ? 784  PHE A N   1 
ATOM   5972  C  CA  . PHE A 1 784 ? 185.240 141.065 139.393 1.00 84.55  ? 784  PHE A CA  1 
ATOM   5973  C  C   . PHE A 1 784 ? 185.194 139.960 138.346 1.00 84.55  ? 784  PHE A C   1 
ATOM   5974  O  O   . PHE A 1 784 ? 185.272 140.225 137.142 1.00 84.55  ? 784  PHE A O   1 
ATOM   5975  C  CB  . PHE A 1 784 ? 186.616 141.123 140.056 1.00 84.55  ? 784  PHE A CB  1 
ATOM   5976  C  CG  . PHE A 1 784 ? 186.867 142.388 140.820 1.00 84.55  ? 784  PHE A CG  1 
ATOM   5977  C  CD1 . PHE A 1 784 ? 186.159 143.539 140.527 1.00 84.55  ? 784  PHE A CD1 1 
ATOM   5978  C  CD2 . PHE A 1 784 ? 187.799 142.421 141.840 1.00 84.55  ? 784  PHE A CD2 1 
ATOM   5979  C  CE1 . PHE A 1 784 ? 186.387 144.703 141.229 1.00 84.55  ? 784  PHE A CE1 1 
ATOM   5980  C  CE2 . PHE A 1 784 ? 188.030 143.583 142.548 1.00 84.55  ? 784  PHE A CE2 1 
ATOM   5981  C  CZ  . PHE A 1 784 ? 187.323 144.725 142.242 1.00 84.55  ? 784  PHE A CZ  1 
ATOM   5982  N  N   . CYS A 1 785 ? 185.064 138.708 138.791 1.00 87.65  ? 785  CYS A N   1 
ATOM   5983  C  CA  . CYS A 1 785 ? 184.969 137.594 137.852 1.00 87.65  ? 785  CYS A CA  1 
ATOM   5984  C  C   . CYS A 1 785 ? 183.714 137.706 136.995 1.00 87.65  ? 785  CYS A C   1 
ATOM   5985  O  O   . CYS A 1 785 ? 183.750 137.455 135.782 1.00 87.65  ? 785  CYS A O   1 
ATOM   5986  C  CB  . CYS A 1 785 ? 184.980 136.266 138.610 1.00 87.65  ? 785  CYS A CB  1 
ATOM   5987  S  SG  . CYS A 1 785 ? 186.614 135.700 139.137 1.00 87.65  ? 785  CYS A SG  1 
ATOM   5988  N  N   . LEU A 1 786 ? 182.595 138.089 137.613 1.00 88.45  ? 786  LEU A N   1 
ATOM   5989  C  CA  . LEU A 1 786 ? 181.342 138.242 136.881 1.00 88.45  ? 786  LEU A CA  1 
ATOM   5990  C  C   . LEU A 1 786 ? 181.468 139.299 135.792 1.00 88.45  ? 786  LEU A C   1 
ATOM   5991  O  O   . LEU A 1 786 ? 181.010 139.103 134.661 1.00 88.45  ? 786  LEU A O   1 
ATOM   5992  C  CB  . LEU A 1 786 ? 180.217 138.603 137.851 1.00 88.45  ? 786  LEU A CB  1 
ATOM   5993  C  CG  . LEU A 1 786 ? 178.829 138.836 137.256 1.00 88.45  ? 786  LEU A CG  1 
ATOM   5994  C  CD1 . LEU A 1 786 ? 178.171 137.519 136.882 1.00 88.45  ? 786  LEU A CD1 1 
ATOM   5995  C  CD2 . LEU A 1 786 ? 177.958 139.624 138.222 1.00 88.45  ? 786  LEU A CD2 1 
ATOM   5996  N  N   . MET A 1 787 ? 182.086 140.435 136.118 1.00 91.00  ? 787  MET A N   1 
ATOM   5997  C  CA  . MET A 1 787 ? 182.259 141.486 135.121 1.00 91.00  ? 787  MET A CA  1 
ATOM   5998  C  C   . MET A 1 787 ? 183.292 141.105 134.067 1.00 91.00  ? 787  MET A C   1 
ATOM   5999  O  O   . MET A 1 787 ? 183.188 141.543 132.916 1.00 91.00  ? 787  MET A O   1 
ATOM   6000  C  CB  . MET A 1 787 ? 182.647 142.799 135.799 1.00 91.00  ? 787  MET A CB  1 
ATOM   6001  C  CG  . MET A 1 787 ? 181.562 143.381 136.686 1.00 91.00  ? 787  MET A CG  1 
ATOM   6002  S  SD  . MET A 1 787 ? 180.044 143.694 135.767 1.00 91.00  ? 787  MET A SD  1 
ATOM   6003  C  CE  . MET A 1 787 ? 180.599 144.933 134.601 1.00 91.00  ? 787  MET A CE  1 
ATOM   6004  N  N   . TRP A 1 788 ? 184.293 140.302 134.437 1.00 94.78  ? 788  TRP A N   1 
ATOM   6005  C  CA  . TRP A 1 788 ? 185.349 139.956 133.493 1.00 94.78  ? 788  TRP A CA  1 
ATOM   6006  C  C   . TRP A 1 788 ? 184.866 138.944 132.459 1.00 94.78  ? 788  TRP A C   1 
ATOM   6007  O  O   . TRP A 1 788 ? 185.075 139.128 131.255 1.00 94.78  ? 788  TRP A O   1 
ATOM   6008  C  CB  . TRP A 1 788 ? 186.564 139.416 134.246 1.00 94.78  ? 788  TRP A CB  1 
ATOM   6009  C  CG  . TRP A 1 788 ? 187.734 139.132 133.361 1.00 94.78  ? 788  TRP A CG  1 
ATOM   6010  C  CD1 . TRP A 1 788 ? 188.149 137.913 132.916 1.00 94.78  ? 788  TRP A CD1 1 
ATOM   6011  C  CD2 . TRP A 1 788 ? 188.643 140.091 132.811 1.00 94.78  ? 788  TRP A CD2 1 
ATOM   6012  N  NE1 . TRP A 1 788 ? 189.261 138.051 132.123 1.00 94.78  ? 788  TRP A NE1 1 
ATOM   6013  C  CE2 . TRP A 1 788 ? 189.585 139.380 132.043 1.00 94.78  ? 788  TRP A CE2 1 
ATOM   6014  C  CE3 . TRP A 1 788 ? 188.752 141.481 132.894 1.00 94.78  ? 788  TRP A CE3 1 
ATOM   6015  C  CZ2 . TRP A 1 788 ? 190.621 140.012 131.361 1.00 94.78  ? 788  TRP A CZ2 1 
ATOM   6016  C  CZ3 . TRP A 1 788 ? 189.780 142.107 132.217 1.00 94.78  ? 788  TRP A CZ3 1 
ATOM   6017  C  CH2 . TRP A 1 788 ? 190.701 141.372 131.461 1.00 94.78  ? 788  TRP A CH2 1 
ATOM   6018  N  N   . TRP A 1 789 ? 184.219 137.868 132.906 1.00 91.35  ? 789  TRP A N   1 
ATOM   6019  C  CA  . TRP A 1 789 ? 183.817 136.796 132.000 1.00 91.35  ? 789  TRP A CA  1 
ATOM   6020  C  C   . TRP A 1 789 ? 182.370 136.907 131.534 1.00 91.35  ? 789  TRP A C   1 
ATOM   6021  O  O   . TRP A 1 789 ? 182.108 136.888 130.327 1.00 91.35  ? 789  TRP A O   1 
ATOM   6022  C  CB  . TRP A 1 789 ? 184.049 135.429 132.652 1.00 91.35  ? 789  TRP A CB  1 
ATOM   6023  C  CG  . TRP A 1 789 ? 185.493 135.044 132.723 1.00 91.35  ? 789  TRP A CG  1 
ATOM   6024  C  CD1 . TRP A 1 789 ? 186.201 134.349 131.785 1.00 91.35  ? 789  TRP A CD1 1 
ATOM   6025  C  CD2 . TRP A 1 789 ? 186.411 135.329 133.784 1.00 91.35  ? 789  TRP A CD2 1 
ATOM   6026  N  NE1 . TRP A 1 789 ? 187.501 134.186 132.196 1.00 91.35  ? 789  TRP A NE1 1 
ATOM   6027  C  CE2 . TRP A 1 789 ? 187.655 134.778 133.421 1.00 91.35  ? 789  TRP A CE2 1 
ATOM   6028  C  CE3 . TRP A 1 789 ? 186.302 135.997 135.006 1.00 91.35  ? 789  TRP A CE3 1 
ATOM   6029  C  CZ2 . TRP A 1 789 ? 188.781 134.876 134.235 1.00 91.35  ? 789  TRP A CZ2 1 
ATOM   6030  C  CZ3 . TRP A 1 789 ? 187.421 136.095 135.813 1.00 91.35  ? 789  TRP A CZ3 1 
ATOM   6031  C  CH2 . TRP A 1 789 ? 188.643 135.535 135.424 1.00 91.35  ? 789  TRP A CH2 1 
ATOM   6032  N  N   . VAL A 1 790 ? 181.420 137.014 132.465 1.00 92.19  ? 790  VAL A N   1 
ATOM   6033  C  CA  . VAL A 1 790 ? 180.010 136.984 132.087 1.00 92.19  ? 790  VAL A CA  1 
ATOM   6034  C  C   . VAL A 1 790 ? 179.651 138.190 131.226 1.00 92.19  ? 790  VAL A C   1 
ATOM   6035  O  O   . VAL A 1 790 ? 178.964 138.056 130.207 1.00 92.19  ? 790  VAL A O   1 
ATOM   6036  C  CB  . VAL A 1 790 ? 179.125 136.894 133.343 1.00 92.19  ? 790  VAL A CB  1 
ATOM   6037  C  CG1 . VAL A 1 790 ? 177.657 137.054 132.976 1.00 92.19  ? 790  VAL A CG1 1 
ATOM   6038  C  CG2 . VAL A 1 790 ? 179.358 135.569 134.054 1.00 92.19  ? 790  VAL A CG2 1 
ATOM   6039  N  N   . PHE A 1 791 ? 180.111 139.379 131.609 1.00 92.05  ? 791  PHE A N   1 
ATOM   6040  C  CA  . PHE A 1 791 ? 179.788 140.598 130.880 1.00 92.05  ? 791  PHE A CA  1 
ATOM   6041  C  C   . PHE A 1 791 ? 180.861 141.004 129.879 1.00 92.05  ? 791  PHE A C   1 
ATOM   6042  O  O   . PHE A 1 791 ? 180.713 142.040 129.222 1.00 92.05  ? 791  PHE A O   1 
ATOM   6043  C  CB  . PHE A 1 791 ? 179.519 141.743 131.861 1.00 92.05  ? 791  PHE A CB  1 
ATOM   6044  C  CG  . PHE A 1 791 ? 178.185 141.646 132.542 1.00 92.05  ? 791  PHE A CG  1 
ATOM   6045  C  CD1 . PHE A 1 791 ? 177.988 140.760 133.588 1.00 92.05  ? 791  PHE A CD1 1 
ATOM   6046  C  CD2 . PHE A 1 791 ? 177.122 142.429 132.124 1.00 92.05  ? 791  PHE A CD2 1 
ATOM   6047  C  CE1 . PHE A 1 791 ? 176.759 140.664 134.212 1.00 92.05  ? 791  PHE A CE1 1 
ATOM   6048  C  CE2 . PHE A 1 791 ? 175.891 142.338 132.745 1.00 92.05  ? 791  PHE A CE2 1 
ATOM   6049  C  CZ  . PHE A 1 791 ? 175.709 141.454 133.788 1.00 92.05  ? 791  PHE A CZ  1 
ATOM   6050  N  N   . HIS A 1 792 ? 181.930 140.216 129.746 1.00 91.85  ? 792  HIS A N   1 
ATOM   6051  C  CA  . HIS A 1 792 ? 182.923 140.382 128.682 1.00 91.85  ? 792  HIS A CA  1 
ATOM   6052  C  C   . HIS A 1 792 ? 183.558 141.773 128.701 1.00 91.85  ? 792  HIS A C   1 
ATOM   6053  O  O   . HIS A 1 792 ? 183.654 142.454 127.678 1.00 91.85  ? 792  HIS A O   1 
ATOM   6054  C  CB  . HIS A 1 792 ? 182.307 140.082 127.313 1.00 91.85  ? 792  HIS A CB  1 
ATOM   6055  C  CG  . HIS A 1 792 ? 181.606 138.761 127.245 1.00 91.85  ? 792  HIS A CG  1 
ATOM   6056  N  ND1 . HIS A 1 792 ? 180.234 138.648 127.171 1.00 91.85  ? 792  HIS A ND1 1 
ATOM   6057  C  CD2 . HIS A 1 792 ? 182.088 137.495 127.242 1.00 91.85  ? 792  HIS A CD2 1 
ATOM   6058  C  CE1 . HIS A 1 792 ? 179.902 137.370 127.123 1.00 91.85  ? 792  HIS A CE1 1 
ATOM   6059  N  NE2 . HIS A 1 792 ? 181.008 136.650 127.165 1.00 91.85  ? 792  HIS A NE2 1 
ATOM   6060  N  N   . ALA A 1 793 ? 183.991 142.197 129.883 1.00 92.91  ? 793  ALA A N   1 
ATOM   6061  C  CA  . ALA A 1 793 ? 184.770 143.427 130.026 1.00 92.91  ? 793  ALA A CA  1 
ATOM   6062  C  C   . ALA A 1 793 ? 186.262 143.100 130.068 1.00 92.91  ? 793  ALA A C   1 
ATOM   6063  O  O   . ALA A 1 793 ? 186.958 143.328 131.057 1.00 92.91  ? 793  ALA A O   1 
ATOM   6064  C  CB  . ALA A 1 793 ? 184.330 144.191 131.270 1.00 92.91  ? 793  ALA A CB  1 
ATOM   6065  N  N   . ASN A 1 794 ? 186.748 142.550 128.956 1.00 96.54  ? 794  ASN A N   1 
ATOM   6066  C  CA  . ASN A 1 794 ? 188.091 141.991 128.888 1.00 96.54  ? 794  ASN A CA  1 
ATOM   6067  C  C   . ASN A 1 794 ? 189.143 142.976 128.395 1.00 96.54  ? 794  ASN A C   1 
ATOM   6068  O  O   . ASN A 1 794 ? 190.329 142.630 128.384 1.00 96.54  ? 794  ASN A O   1 
ATOM   6069  C  CB  . ASN A 1 794 ? 188.095 140.758 127.978 1.00 96.54  ? 794  ASN A CB  1 
ATOM   6070  C  CG  . ASN A 1 794 ? 187.403 139.566 128.609 1.00 96.54  ? 794  ASN A CG  1 
ATOM   6071  O  OD1 . ASN A 1 794 ? 187.565 139.298 129.799 1.00 96.54  ? 794  ASN A OD1 1 
ATOM   6072  N  ND2 . ASN A 1 794 ? 186.622 138.846 127.813 1.00 96.54  ? 794  ASN A ND2 1 
ATOM   6073  N  N   . THR A 1 795 ? 188.756 144.178 127.993 1.00 95.84  ? 795  THR A N   1 
ATOM   6074  C  CA  . THR A 1 795 ? 189.677 145.147 127.423 1.00 95.84  ? 795  THR A CA  1 
ATOM   6075  C  C   . THR A 1 795 ? 189.510 146.495 128.103 1.00 95.84  ? 795  THR A C   1 
ATOM   6076  O  O   . THR A 1 795 ? 188.428 146.819 128.605 1.00 95.84  ? 795  THR A O   1 
ATOM   6077  C  CB  . THR A 1 795 ? 189.454 145.306 125.911 1.00 95.84  ? 795  THR A CB  1 
ATOM   6078  O  OG1 . THR A 1 795 ? 188.067 145.555 125.654 1.00 95.84  ? 795  THR A OG1 1 
ATOM   6079  C  CG2 . THR A 1 795 ? 189.887 144.049 125.172 1.00 95.84  ? 795  THR A CG2 1 
ATOM   6080  N  N   . PRO A 1 796 ? 190.573 147.304 128.146 1.00 93.45  ? 796  PRO A N   1 
ATOM   6081  C  CA  . PRO A 1 796 ? 190.430 148.668 128.680 1.00 93.45  ? 796  PRO A CA  1 
ATOM   6082  C  C   . PRO A 1 796 ? 189.436 149.516 127.908 1.00 93.45  ? 796  PRO A C   1 
ATOM   6083  O  O   . PRO A 1 796 ? 188.842 150.435 128.485 1.00 93.45  ? 796  PRO A O   1 
ATOM   6084  C  CB  . PRO A 1 796 ? 191.853 149.234 128.577 1.00 93.45  ? 796  PRO A CB  1 
ATOM   6085  C  CG  . PRO A 1 796 ? 192.738 148.037 128.591 1.00 93.45  ? 796  PRO A CG  1 
ATOM   6086  C  CD  . PRO A 1 796 ? 191.978 146.958 127.876 1.00 93.45  ? 796  PRO A CD  1 
ATOM   6087  N  N   . GLU A 1 797 ? 189.240 149.238 126.616 1.00 95.67  ? 797  GLU A N   1 
ATOM   6088  C  CA  . GLU A 1 797 ? 188.295 150.017 125.822 1.00 95.67  ? 797  GLU A CA  1 
ATOM   6089  C  C   . GLU A 1 797 ? 186.885 149.941 126.392 1.00 95.67  ? 797  GLU A C   1 
ATOM   6090  O  O   . GLU A 1 797 ? 186.095 150.876 126.223 1.00 95.67  ? 797  GLU A O   1 
ATOM   6091  C  CB  . GLU A 1 797 ? 188.306 149.539 124.369 1.00 95.67  ? 797  GLU A CB  1 
ATOM   6092  C  CG  . GLU A 1 797 ? 189.578 149.878 123.600 1.00 95.67  ? 797  GLU A CG  1 
ATOM   6093  C  CD  . GLU A 1 797 ? 190.756 149.005 123.991 1.00 95.67  ? 797  GLU A CD  1 
ATOM   6094  O  OE1 . GLU A 1 797 ? 190.679 147.775 123.790 1.00 95.67  ? 797  GLU A OE1 1 
ATOM   6095  O  OE2 . GLU A 1 797 ? 191.757 149.550 124.500 1.00 95.67  ? 797  GLU A OE2 1 
ATOM   6096  N  N   . THR A 1 798 ? 186.550 148.841 127.067 1.00 93.54  ? 798  THR A N   1 
ATOM   6097  C  CA  . THR A 1 798 ? 185.267 148.684 127.739 1.00 93.54  ? 798  THR A CA  1 
ATOM   6098  C  C   . THR A 1 798 ? 185.422 148.676 129.258 1.00 93.54  ? 798  THR A C   1 
ATOM   6099  O  O   . THR A 1 798 ? 184.591 148.106 129.970 1.00 93.54  ? 798  THR A O   1 
ATOM   6100  C  CB  . THR A 1 798 ? 184.564 147.412 127.267 1.00 93.54  ? 798  THR A CB  1 
ATOM   6101  O  OG1 . THR A 1 798 ? 183.322 147.263 127.968 1.00 93.54  ? 798  THR A OG1 1 
ATOM   6102  C  CG2 . THR A 1 798 ? 185.435 146.189 127.519 1.00 93.54  ? 798  THR A CG2 1 
ATOM   6103  N  N   . GLN A 1 799 ? 186.486 149.306 129.767 1.00 88.53  ? 799  GLN A N   1 
ATOM   6104  C  CA  . GLN A 1 799 ? 186.718 149.316 131.208 1.00 88.53  ? 799  GLN A CA  1 
ATOM   6105  C  C   . GLN A 1 799 ? 185.643 150.101 131.948 1.00 88.53  ? 799  GLN A C   1 
ATOM   6106  O  O   . GLN A 1 799 ? 185.365 149.812 133.118 1.00 88.53  ? 799  GLN A O   1 
ATOM   6107  C  CB  . GLN A 1 799 ? 188.102 149.890 131.517 1.00 88.53  ? 799  GLN A CB  1 
ATOM   6108  C  CG  . GLN A 1 799 ? 188.199 151.404 131.404 1.00 88.53  ? 799  GLN A CG  1 
ATOM   6109  C  CD  . GLN A 1 799 ? 189.559 151.932 131.811 1.00 88.53  ? 799  GLN A CD  1 
ATOM   6110  O  OE1 . GLN A 1 799 ? 190.576 151.263 131.630 1.00 88.53  ? 799  GLN A OE1 1 
ATOM   6111  N  NE2 . GLN A 1 799 ? 189.585 153.140 132.362 1.00 88.53  ? 799  GLN A NE2 1 
ATOM   6112  N  N   . THR A 1 800 ? 185.023 151.082 131.286 1.00 87.18  ? 800  THR A N   1 
ATOM   6113  C  CA  . THR A 1 800 ? 184.013 151.902 131.947 1.00 87.18  ? 800  THR A CA  1 
ATOM   6114  C  C   . THR A 1 800 ? 182.841 151.052 132.417 1.00 87.18  ? 800  THR A C   1 
ATOM   6115  O  O   . THR A 1 800 ? 182.287 151.286 133.498 1.00 87.18  ? 800  THR A O   1 
ATOM   6116  C  CB  . THR A 1 800 ? 183.534 153.006 131.004 1.00 87.18  ? 800  THR A CB  1 
ATOM   6117  O  OG1 . THR A 1 800 ? 184.654 153.794 130.584 1.00 87.18  ? 800  THR A OG1 1 
ATOM   6118  C  CG2 . THR A 1 800 ? 182.529 153.907 131.704 1.00 87.18  ? 800  THR A CG2 1 
ATOM   6119  N  N   . LEU A 1 801 ? 182.451 150.056 131.619 1.00 89.54  ? 801  LEU A N   1 
ATOM   6120  C  CA  . LEU A 1 801 ? 181.427 149.116 132.060 1.00 89.54  ? 801  LEU A CA  1 
ATOM   6121  C  C   . LEU A 1 801 ? 181.893 148.329 133.278 1.00 89.54  ? 801  LEU A C   1 
ATOM   6122  O  O   . LEU A 1 801 ? 181.116 148.099 134.211 1.00 89.54  ? 801  LEU A O   1 
ATOM   6123  C  CB  . LEU A 1 801 ? 181.059 148.170 130.917 1.00 89.54  ? 801  LEU A CB  1 
ATOM   6124  C  CG  . LEU A 1 801 ? 180.298 146.898 131.298 1.00 89.54  ? 801  LEU A CG  1 
ATOM   6125  C  CD1 . LEU A 1 801 ? 178.823 147.195 131.521 1.00 89.54  ? 801  LEU A CD1 1 
ATOM   6126  C  CD2 . LEU A 1 801 ? 180.480 145.823 130.237 1.00 89.54  ? 801  LEU A CD2 1 
ATOM   6127  N  N   . PHE A 1 802 ? 183.162 147.911 133.287 1.00 86.45  ? 802  PHE A N   1 
ATOM   6128  C  CA  . PHE A 1 802 ? 183.669 147.096 134.386 1.00 86.45  ? 802  PHE A CA  1 
ATOM   6129  C  C   . PHE A 1 802 ? 183.631 147.861 135.703 1.00 86.45  ? 802  PHE A C   1 
ATOM   6130  O  O   . PHE A 1 802 ? 183.040 147.399 136.687 1.00 86.45  ? 802  PHE A O   1 
ATOM   6131  C  CB  . PHE A 1 802 ? 185.095 146.636 134.072 1.00 86.45  ? 802  PHE A CB  1 
ATOM   6132  C  CG  . PHE A 1 802 ? 185.693 145.729 135.114 1.00 86.45  ? 802  PHE A CG  1 
ATOM   6133  C  CD1 . PHE A 1 802 ? 186.360 146.249 136.212 1.00 86.45  ? 802  PHE A CD1 1 
ATOM   6134  C  CD2 . PHE A 1 802 ? 185.607 144.354 134.981 1.00 86.45  ? 802  PHE A CD2 1 
ATOM   6135  C  CE1 . PHE A 1 802 ? 186.912 145.415 137.164 1.00 86.45  ? 802  PHE A CE1 1 
ATOM   6136  C  CE2 . PHE A 1 802 ? 186.159 143.516 135.931 1.00 86.45  ? 802  PHE A CE2 1 
ATOM   6137  C  CZ  . PHE A 1 802 ? 186.812 144.047 137.023 1.00 86.45  ? 802  PHE A CZ  1 
ATOM   6138  N  N   . GLN A 1 803 ? 184.229 149.055 135.727 1.00 85.39  ? 803  GLN A N   1 
ATOM   6139  C  CA  . GLN A 1 803 ? 184.363 149.798 136.976 1.00 85.39  ? 803  GLN A CA  1 
ATOM   6140  C  C   . GLN A 1 803 ? 183.000 150.127 137.568 1.00 85.39  ? 803  GLN A C   1 
ATOM   6141  O  O   . GLN A 1 803 ? 182.737 149.847 138.745 1.00 85.39  ? 803  GLN A O   1 
ATOM   6142  C  CB  . GLN A 1 803 ? 185.174 151.071 136.737 1.00 85.39  ? 803  GLN A CB  1 
ATOM   6143  C  CG  . GLN A 1 803 ? 186.507 150.827 136.053 1.00 85.39  ? 803  GLN A CG  1 
ATOM   6144  C  CD  . GLN A 1 803 ? 187.240 152.111 135.729 1.00 85.39  ? 803  GLN A CD  1 
ATOM   6145  O  OE1 . GLN A 1 803 ? 186.645 153.069 135.238 1.00 85.39  ? 803  GLN A OE1 1 
ATOM   6146  N  NE2 . GLN A 1 803 ? 188.538 152.138 136.005 1.00 85.39  ? 803  GLN A NE2 1 
ATOM   6147  N  N   . SER A 1 804 ? 182.109 150.699 136.756 1.00 81.76  ? 804  SER A N   1 
ATOM   6148  C  CA  . SER A 1 804 ? 180.756 150.973 137.226 1.00 81.76  ? 804  SER A CA  1 
ATOM   6149  C  C   . SER A 1 804 ? 180.081 149.698 137.710 1.00 81.76  ? 804  SER A C   1 
ATOM   6150  O  O   . SER A 1 804 ? 179.320 149.722 138.685 1.00 81.76  ? 804  SER A O   1 
ATOM   6151  C  CB  . SER A 1 804 ? 179.937 151.628 136.114 1.00 81.76  ? 804  SER A CB  1 
ATOM   6152  O  OG  . SER A 1 804 ? 178.619 151.906 136.552 1.00 81.76  ? 804  SER A OG  1 
ATOM   6153  N  N   . GLY A 1 805 ? 180.375 148.569 137.061 1.00 82.98  ? 805  GLY A N   1 
ATOM   6154  C  CA  . GLY A 1 805 ? 179.801 147.308 137.499 1.00 82.98  ? 805  GLY A CA  1 
ATOM   6155  C  C   . GLY A 1 805 ? 180.161 146.981 138.934 1.00 82.98  ? 805  GLY A C   1 
ATOM   6156  O  O   . GLY A 1 805 ? 179.346 146.436 139.682 1.00 82.98  ? 805  GLY A O   1 
ATOM   6157  N  N   . TRP A 1 806 ? 181.389 147.311 139.339 1.00 77.12  ? 806  TRP A N   1 
ATOM   6158  C  CA  . TRP A 1 806 ? 181.759 147.148 140.739 1.00 77.12  ? 806  TRP A CA  1 
ATOM   6159  C  C   . TRP A 1 806 ? 181.164 148.251 141.603 1.00 77.12  ? 806  TRP A C   1 
ATOM   6160  O  O   . TRP A 1 806 ? 180.800 148.001 142.759 1.00 77.12  ? 806  TRP A O   1 
ATOM   6161  C  CB  . TRP A 1 806 ? 183.281 147.125 140.881 1.00 77.12  ? 806  TRP A CB  1 
ATOM   6162  C  CG  . TRP A 1 806 ? 183.750 146.778 142.258 1.00 77.12  ? 806  TRP A CG  1 
ATOM   6163  C  CD1 . TRP A 1 806 ? 183.086 146.032 143.187 1.00 77.12  ? 806  TRP A CD1 1 
ATOM   6164  C  CD2 . TRP A 1 806 ? 184.985 147.169 142.867 1.00 77.12  ? 806  TRP A CD2 1 
ATOM   6165  N  NE1 . TRP A 1 806 ? 183.832 145.931 144.335 1.00 77.12  ? 806  TRP A NE1 1 
ATOM   6166  C  CE2 . TRP A 1 806 ? 185.004 146.620 144.164 1.00 77.12  ? 806  TRP A CE2 1 
ATOM   6167  C  CE3 . TRP A 1 806 ? 186.080 147.926 142.439 1.00 77.12  ? 806  TRP A CE3 1 
ATOM   6168  C  CZ2 . TRP A 1 806 ? 186.071 146.807 145.038 1.00 77.12  ? 806  TRP A CZ2 1 
ATOM   6169  C  CZ3 . TRP A 1 806 ? 187.138 148.110 143.308 1.00 77.12  ? 806  TRP A CZ3 1 
ATOM   6170  C  CH2 . TRP A 1 806 ? 187.127 147.553 144.592 1.00 77.12  ? 806  TRP A CH2 1 
ATOM   6171  N  N   . PHE A 1 807 ? 181.029 149.461 141.050 1.00 70.07  ? 807  PHE A N   1 
ATOM   6172  C  CA  . PHE A 1 807 ? 180.658 150.620 141.857 1.00 70.07  ? 807  PHE A CA  1 
ATOM   6173  C  C   . PHE A 1 807 ? 179.335 150.392 142.576 1.00 70.07  ? 807  PHE A C   1 
ATOM   6174  O  O   . PHE A 1 807 ? 179.243 150.560 143.798 1.00 70.07  ? 807  PHE A O   1 
ATOM   6175  C  CB  . PHE A 1 807 ? 180.591 151.866 140.971 1.00 70.07  ? 807  PHE A CB  1 
ATOM   6176  C  CG  . PHE A 1 807 ? 180.021 153.075 141.658 1.00 70.07  ? 807  PHE A CG  1 
ATOM   6177  C  CD1 . PHE A 1 807 ? 180.835 153.913 142.399 1.00 70.07  ? 807  PHE A CD1 1 
ATOM   6178  C  CD2 . PHE A 1 807 ? 178.676 153.387 141.545 1.00 70.07  ? 807  PHE A CD2 1 
ATOM   6179  C  CE1 . PHE A 1 807 ? 180.317 155.028 143.027 1.00 70.07  ? 807  PHE A CE1 1 
ATOM   6180  C  CE2 . PHE A 1 807 ? 178.153 154.500 142.171 1.00 70.07  ? 807  PHE A CE2 1 
ATOM   6181  C  CZ  . PHE A 1 807 ? 178.975 155.322 142.912 1.00 70.07  ? 807  PHE A CZ  1 
ATOM   6182  N  N   . VAL A 1 808 ? 178.305 149.976 141.837 1.00 72.84  ? 808  VAL A N   1 
ATOM   6183  C  CA  . VAL A 1 808 ? 177.006 149.728 142.452 1.00 72.84  ? 808  VAL A CA  1 
ATOM   6184  C  C   . VAL A 1 808 ? 177.108 148.617 143.486 1.00 72.84  ? 808  VAL A C   1 
ATOM   6185  O  O   . VAL A 1 808 ? 176.446 148.665 144.529 1.00 72.84  ? 808  VAL A O   1 
ATOM   6186  C  CB  . VAL A 1 808 ? 175.956 149.407 141.371 1.00 72.84  ? 808  VAL A CB  1 
ATOM   6187  C  CG1 . VAL A 1 808 ? 174.565 149.361 141.981 1.00 72.84  ? 808  VAL A CG1 1 
ATOM   6188  C  CG2 . VAL A 1 808 ? 176.021 150.433 140.254 1.00 72.84  ? 808  VAL A CG2 1 
ATOM   6189  N  N   . VAL A 1 809 ? 177.932 147.601 143.223 1.00 73.47  ? 809  VAL A N   1 
ATOM   6190  C  CA  . VAL A 1 809 ? 178.165 146.574 144.232 1.00 73.47  ? 809  VAL A CA  1 
ATOM   6191  C  C   . VAL A 1 809 ? 178.949 147.150 145.403 1.00 73.47  ? 809  VAL A C   1 
ATOM   6192  O  O   . VAL A 1 809 ? 178.692 146.813 146.566 1.00 73.47  ? 809  VAL A O   1 
ATOM   6193  C  CB  . VAL A 1 809 ? 178.881 145.361 143.609 1.00 73.47  ? 809  VAL A CB  1 
ATOM   6194  C  CG1 . VAL A 1 809 ? 179.261 144.355 144.684 1.00 73.47  ? 809  VAL A CG1 1 
ATOM   6195  C  CG2 . VAL A 1 809 ? 177.992 144.707 142.574 1.00 73.47  ? 809  VAL A CG2 1 
ATOM   6196  N  N   . GLY A 1 810 ? 179.907 148.035 145.121 1.00 70.03  ? 810  GLY A N   1 
ATOM   6197  C  CA  . GLY A 1 810 ? 180.736 148.569 146.189 1.00 70.03  ? 810  GLY A CA  1 
ATOM   6198  C  C   . GLY A 1 810 ? 179.955 149.422 147.170 1.00 70.03  ? 810  GLY A C   1 
ATOM   6199  O  O   . GLY A 1 810 ? 180.109 149.291 148.386 1.00 70.03  ? 810  GLY A O   1 
ATOM   6200  N  N   . LEU A 1 811 ? 179.106 150.311 146.653 1.00 66.17  ? 811  LEU A N   1 
ATOM   6201  C  CA  . LEU A 1 811 ? 178.403 151.249 147.521 1.00 66.17  ? 811  LEU A CA  1 
ATOM   6202  C  C   . LEU A 1 811 ? 177.262 150.586 148.285 1.00 66.17  ? 811  LEU A C   1 
ATOM   6203  O  O   . LEU A 1 811 ? 177.111 150.811 149.491 1.00 66.17  ? 811  LEU A O   1 
ATOM   6204  C  CB  . LEU A 1 811 ? 177.876 152.424 146.701 1.00 66.17  ? 811  LEU A CB  1 
ATOM   6205  C  CG  . LEU A 1 811 ? 177.001 153.422 147.457 1.00 66.17  ? 811  LEU A CG  1 
ATOM   6206  C  CD1 . LEU A 1 811 ? 177.733 153.976 148.670 1.00 66.17  ? 811  LEU A CD1 1 
ATOM   6207  C  CD2 . LEU A 1 811 ? 176.564 154.540 146.535 1.00 66.17  ? 811  LEU A CD2 1 
ATOM   6208  N  N   . LEU A 1 812 ? 176.449 149.774 147.607 1.00 68.17  ? 812  LEU A N   1 
ATOM   6209  C  CA  . LEU A 1 812 ? 175.264 149.219 148.254 1.00 68.17  ? 812  LEU A CA  1 
ATOM   6210  C  C   . LEU A 1 812 ? 175.630 148.187 149.313 1.00 68.17  ? 812  LEU A C   1 
ATOM   6211  O  O   . LEU A 1 812 ? 175.110 148.235 150.435 1.00 68.17  ? 812  LEU A O   1 
ATOM   6212  C  CB  . LEU A 1 812 ? 174.321 148.613 147.214 1.00 68.17  ? 812  LEU A CB  1 
ATOM   6213  C  CG  . LEU A 1 812 ? 173.350 149.573 146.517 1.00 68.17  ? 812  LEU A CG  1 
ATOM   6214  C  CD1 . LEU A 1 812 ? 174.053 150.503 145.539 1.00 68.17  ? 812  LEU A CD1 1 
ATOM   6215  C  CD2 . LEU A 1 812 ? 172.246 148.790 145.823 1.00 68.17  ? 812  LEU A CD2 1 
ATOM   6216  N  N   . SER A 1 813 ? 176.521 147.248 148.983 1.00 65.94  ? 813  SER A N   1 
ATOM   6217  C  CA  . SER A 1 813 ? 176.921 146.240 149.961 1.00 65.94  ? 813  SER A CA  1 
ATOM   6218  C  C   . SER A 1 813 ? 177.509 146.897 151.202 1.00 65.94  ? 813  SER A C   1 
ATOM   6219  O  O   . SER A 1 813 ? 177.106 146.592 152.331 1.00 65.94  ? 813  SER A O   1 
ATOM   6220  C  CB  . SER A 1 813 ? 177.923 145.270 149.337 1.00 65.94  ? 813  SER A CB  1 
ATOM   6221  O  OG  . SER A 1 813 ? 179.069 145.958 148.868 1.00 65.94  ? 813  SER A OG  1 
ATOM   6222  N  N   . GLN A 1 814 ? 178.442 147.832 151.002 1.00 65.76  ? 814  GLN A N   1 
ATOM   6223  C  CA  . GLN A 1 814 ? 178.994 148.600 152.113 1.00 65.76  ? 814  GLN A CA  1 
ATOM   6224  C  C   . GLN A 1 814 ? 177.892 149.261 152.928 1.00 65.76  ? 814  GLN A C   1 
ATOM   6225  O  O   . GLN A 1 814 ? 177.989 149.360 154.157 1.00 65.76  ? 814  GLN A O   1 
ATOM   6226  C  CB  . GLN A 1 814 ? 179.966 149.652 151.578 1.00 65.76  ? 814  GLN A CB  1 
ATOM   6227  C  CG  . GLN A 1 814 ? 180.874 150.261 152.623 1.00 65.76  ? 814  GLN A CG  1 
ATOM   6228  C  CD  . GLN A 1 814 ? 181.814 151.295 152.039 1.00 65.76  ? 814  GLN A CD  1 
ATOM   6229  O  OE1 . GLN A 1 814 ? 181.642 151.734 150.903 1.00 65.76  ? 814  GLN A OE1 1 
ATOM   6230  N  NE2 . GLN A 1 814 ? 182.816 151.691 152.816 1.00 65.76  ? 814  GLN A NE2 1 
ATOM   6231  N  N   . THR A 1 815 ? 176.833 149.720 152.261 1.00 64.32  ? 815  THR A N   1 
ATOM   6232  C  CA  . THR A 1 815 ? 175.709 150.305 152.977 1.00 64.32  ? 815  THR A CA  1 
ATOM   6233  C  C   . THR A 1 815 ? 174.835 149.232 153.618 1.00 64.32  ? 815  THR A C   1 
ATOM   6234  O  O   . THR A 1 815 ? 174.326 149.423 154.728 1.00 64.32  ? 815  THR A O   1 
ATOM   6235  C  CB  . THR A 1 815 ? 174.883 151.175 152.030 1.00 64.32  ? 815  THR A CB  1 
ATOM   6236  O  OG1 . THR A 1 815 ? 175.743 152.112 151.372 1.00 64.32  ? 815  THR A OG1 1 
ATOM   6237  C  CG2 . THR A 1 815 ? 173.828 151.943 152.801 1.00 64.32  ? 815  THR A CG2 1 
ATOM   6238  N  N   . LEU A 1 816 ? 174.655 148.095 152.940 1.00 67.07  ? 816  LEU A N   1 
ATOM   6239  C  CA  . LEU A 1 816 ? 173.751 147.071 153.457 1.00 67.07  ? 816  LEU A CA  1 
ATOM   6240  C  C   . LEU A 1 816 ? 174.370 146.315 154.626 1.00 67.07  ? 816  LEU A C   1 
ATOM   6241  O  O   . LEU A 1 816 ? 173.692 146.049 155.627 1.00 67.07  ? 816  LEU A O   1 
ATOM   6242  C  CB  . LEU A 1 816 ? 173.357 146.104 152.342 1.00 67.07  ? 816  LEU A CB  1 
ATOM   6243  C  CG  . LEU A 1 816 ? 172.047 146.431 151.625 1.00 67.07  ? 816  LEU A CG  1 
ATOM   6244  C  CD1 . LEU A 1 816 ? 171.830 145.500 150.446 1.00 67.07  ? 816  LEU A CD1 1 
ATOM   6245  C  CD2 . LEU A 1 816 ? 170.876 146.357 152.593 1.00 67.07  ? 816  LEU A CD2 1 
ATOM   6246  N  N   . ILE A 1 817 ? 175.658 145.979 154.523 1.00 66.88  ? 817  ILE A N   1 
ATOM   6247  C  CA  . ILE A 1 817 ? 176.334 145.155 155.515 1.00 66.88  ? 817  ILE A CA  1 
ATOM   6248  C  C   . ILE A 1 817 ? 176.175 145.684 156.933 1.00 66.88  ? 817  ILE A C   1 
ATOM   6249  O  O   . ILE A 1 817 ? 176.246 144.902 157.886 1.00 66.88  ? 817  ILE A O   1 
ATOM   6250  C  CB  . ILE A 1 817 ? 177.829 145.014 155.148 1.00 66.88  ? 817  ILE A CB  1 
ATOM   6251  C  CG1 . ILE A 1 817 ? 178.487 143.915 155.980 1.00 66.88  ? 817  ILE A CG1 1 
ATOM   6252  C  CG2 . ILE A 1 817 ? 178.561 146.335 155.333 1.00 66.88  ? 817  ILE A CG2 1 
ATOM   6253  C  CD1 . ILE A 1 817 ? 177.943 142.542 155.704 1.00 66.88  ? 817  ILE A CD1 1 
ATOM   6254  N  N   . VAL A 1 818 ? 175.925 146.986 157.091 1.00 64.32  ? 818  VAL A N   1 
ATOM   6255  C  CA  . VAL A 1 818 ? 175.727 147.556 158.420 1.00 64.32  ? 818  VAL A CA  1 
ATOM   6256  C  C   . VAL A 1 818 ? 174.610 146.828 159.152 1.00 64.32  ? 818  VAL A C   1 
ATOM   6257  O  O   . VAL A 1 818 ? 174.790 146.365 160.286 1.00 64.32  ? 818  VAL A O   1 
ATOM   6258  C  CB  . VAL A 1 818 ? 175.443 149.065 158.310 1.00 64.32  ? 818  VAL A CB  1 
ATOM   6259  C  CG1 . VAL A 1 818 ? 174.795 149.581 159.584 1.00 64.32  ? 818  VAL A CG1 1 
ATOM   6260  C  CG2 . VAL A 1 818 ? 176.727 149.817 158.014 1.00 64.32  ? 818  VAL A CG2 1 
ATOM   6261  N  N   . HIS A 1 819 ? 173.461 146.656 158.493 1.00 65.12  ? 819  HIS A N   1 
ATOM   6262  C  CA  . HIS A 1 819 ? 172.333 145.994 159.135 1.00 65.12  ? 819  HIS A CA  1 
ATOM   6263  C  C   . HIS A 1 819 ? 172.635 144.548 159.498 1.00 65.12  ? 819  HIS A C   1 
ATOM   6264  O  O   . HIS A 1 819 ? 171.897 143.960 160.296 1.00 65.12  ? 819  HIS A O   1 
ATOM   6265  C  CB  . HIS A 1 819 ? 171.099 146.055 158.234 1.00 65.12  ? 819  HIS A CB  1 
ATOM   6266  C  CG  . HIS A 1 819 ? 170.603 147.445 157.986 1.00 65.12  ? 819  HIS A CG  1 
ATOM   6267  N  ND1 . HIS A 1 819 ? 169.609 148.026 158.745 1.00 65.12  ? 819  HIS A ND1 1 
ATOM   6268  C  CD2 . HIS A 1 819 ? 170.963 148.371 157.067 1.00 65.12  ? 819  HIS A CD2 1 
ATOM   6269  C  CE1 . HIS A 1 819 ? 169.378 149.248 158.302 1.00 65.12  ? 819  HIS A CE1 1 
ATOM   6270  N  NE2 . HIS A 1 819 ? 170.186 149.483 157.284 1.00 65.12  ? 819  HIS A NE2 1 
ATOM   6271  N  N   . MET A 1 820 ? 173.693 143.967 158.938 1.00 70.53  ? 820  MET A N   1 
ATOM   6272  C  CA  . MET A 1 820 ? 174.108 142.625 159.315 1.00 70.53  ? 820  MET A CA  1 
ATOM   6273  C  C   . MET A 1 820 ? 175.177 142.630 160.401 1.00 70.53  ? 820  MET A C   1 
ATOM   6274  O  O   . MET A 1 820 ? 175.260 141.679 161.184 1.00 70.53  ? 820  MET A O   1 
ATOM   6275  C  CB  . MET A 1 820 ? 174.621 141.869 158.088 1.00 70.53  ? 820  MET A CB  1 
ATOM   6276  C  CG  . MET A 1 820 ? 173.524 141.308 157.203 1.00 70.53  ? 820  MET A CG  1 
ATOM   6277  S  SD  . MET A 1 820 ? 172.652 139.935 157.979 1.00 70.53  ? 820  MET A SD  1 
ATOM   6278  C  CE  . MET A 1 820 ? 170.979 140.239 157.416 1.00 70.53  ? 820  MET A CE  1 
ATOM   6279  N  N   . ILE A 1 821 ? 175.992 143.680 160.477 1.00 64.85  ? 821  ILE A N   1 
ATOM   6280  C  CA  . ILE A 1 821 ? 177.147 143.685 161.368 1.00 64.85  ? 821  ILE A CA  1 
ATOM   6281  C  C   . ILE A 1 821 ? 176.974 144.681 162.516 1.00 64.85  ? 821  ILE A C   1 
ATOM   6282  O  O   . ILE A 1 821 ? 177.950 145.043 163.170 1.00 64.85  ? 821  ILE A O   1 
ATOM   6283  C  CB  . ILE A 1 821 ? 178.452 143.944 160.600 1.00 64.85  ? 821  ILE A CB  1 
ATOM   6284  C  CG1 . ILE A 1 821 ? 178.473 145.363 160.031 1.00 64.85  ? 821  ILE A CG1 1 
ATOM   6285  C  CG2 . ILE A 1 821 ? 178.632 142.916 159.497 1.00 64.85  ? 821  ILE A CG2 1 
ATOM   6286  C  CD1 . ILE A 1 821 ? 179.746 145.703 159.288 1.00 64.85  ? 821  ILE A CD1 1 
ATOM   6287  N  N   . ARG A 1 822 ? 175.748 145.129 162.774 1.00 65.00  ? 822  ARG A N   1 
ATOM   6288  C  CA  . ARG A 1 822 ? 175.505 146.023 163.896 1.00 65.00  ? 822  ARG A CA  1 
ATOM   6289  C  C   . ARG A 1 822 ? 175.049 145.293 165.150 1.00 65.00  ? 822  ARG A C   1 
ATOM   6290  O  O   . ARG A 1 822 ? 175.167 145.847 166.248 1.00 65.00  ? 822  ARG A O   1 
ATOM   6291  C  CB  . ARG A 1 822 ? 174.459 147.077 163.521 1.00 65.00  ? 822  ARG A CB  1 
ATOM   6292  C  CG  . ARG A 1 822 ? 173.105 146.504 163.149 1.00 65.00  ? 822  ARG A CG  1 
ATOM   6293  C  CD  . ARG A 1 822 ? 172.100 147.610 162.885 1.00 65.00  ? 822  ARG A CD  1 
ATOM   6294  N  NE  . ARG A 1 822 ? 171.569 148.163 164.125 1.00 65.00  ? 822  ARG A NE  1 
ATOM   6295  C  CZ  . ARG A 1 822 ? 170.554 147.644 164.802 1.00 65.00  ? 822  ARG A CZ  1 
ATOM   6296  N  NH1 . ARG A 1 822 ? 169.926 146.558 164.382 1.00 65.00  ? 822  ARG A NH1 1 
ATOM   6297  N  NH2 . ARG A 1 822 ? 170.156 148.231 165.927 1.00 65.00  ? 822  ARG A NH2 1 
ATOM   6298  N  N   . THR A 1 823 ? 174.531 144.072 165.018 1.00 75.66  ? 823  THR A N   1 
ATOM   6299  C  CA  . THR A 1 823 ? 174.022 143.319 166.154 1.00 75.66  ? 823  THR A CA  1 
ATOM   6300  C  C   . THR A 1 823 ? 174.518 141.883 166.081 1.00 75.66  ? 823  THR A C   1 
ATOM   6301  O  O   . THR A 1 823 ? 174.715 141.331 164.996 1.00 75.66  ? 823  THR A O   1 
ATOM   6302  C  CB  . THR A 1 823 ? 172.486 143.320 166.202 1.00 75.66  ? 823  THR A CB  1 
ATOM   6303  O  OG1 . THR A 1 823 ? 171.969 142.711 165.013 1.00 75.66  ? 823  THR A OG1 1 
ATOM   6304  C  CG2 . THR A 1 823 ? 171.948 144.738 166.312 1.00 75.66  ? 823  THR A CG2 1 
ATOM   6305  N  N   . ARG A 1 824 ? 174.719 141.283 167.255 1.00 80.76  ? 824  ARG A N   1 
ATOM   6306  C  CA  . ARG A 1 824 ? 175.019 139.859 167.336 1.00 80.76  ? 824  ARG A CA  1 
ATOM   6307  C  C   . ARG A 1 824 ? 173.783 139.001 167.109 1.00 80.76  ? 824  ARG A C   1 
ATOM   6308  O  O   . ARG A 1 824 ? 173.913 137.820 166.769 1.00 80.76  ? 824  ARG A O   1 
ATOM   6309  C  CB  . ARG A 1 824 ? 175.639 139.534 168.698 1.00 80.76  ? 824  ARG A CB  1 
ATOM   6310  C  CG  . ARG A 1 824 ? 176.499 138.281 168.727 1.00 80.76  ? 824  ARG A CG  1 
ATOM   6311  C  CD  . ARG A 1 824 ? 175.728 137.071 169.240 1.00 80.76  ? 824  ARG A CD  1 
ATOM   6312  N  NE  . ARG A 1 824 ? 175.157 137.298 170.562 1.00 80.76  ? 824  ARG A NE  1 
ATOM   6313  C  CZ  . ARG A 1 824 ? 174.215 136.543 171.112 1.00 80.76  ? 824  ARG A CZ  1 
ATOM   6314  N  NH1 . ARG A 1 824 ? 173.712 135.496 170.478 1.00 80.76  ? 824  ARG A NH1 1 
ATOM   6315  N  NH2 . ARG A 1 824 ? 173.768 136.846 172.327 1.00 80.76  ? 824  ARG A NH2 1 
ATOM   6316  N  N   . ARG A 1 825 ? 172.597 139.574 167.277 1.00 83.67  ? 825  ARG A N   1 
ATOM   6317  C  CA  . ARG A 1 825 ? 171.336 138.869 167.119 1.00 83.67  ? 825  ARG A CA  1 
ATOM   6318  C  C   . ARG A 1 825 ? 170.922 138.921 165.647 1.00 83.67  ? 825  ARG A C   1 
ATOM   6319  O  O   . ARG A 1 825 ? 171.417 139.746 164.875 1.00 83.67  ? 825  ARG A O   1 
ATOM   6320  C  CB  . ARG A 1 825 ? 170.307 139.487 168.064 1.00 83.67  ? 825  ARG A CB  1 
ATOM   6321  C  CG  . ARG A 1 825 ? 170.710 139.349 169.529 1.00 83.67  ? 825  ARG A CG  1 
ATOM   6322  C  CD  . ARG A 1 825 ? 169.778 140.085 170.483 1.00 83.67  ? 825  ARG A CD  1 
ATOM   6323  N  NE  . ARG A 1 825 ? 168.455 139.486 170.595 1.00 83.67  ? 825  ARG A NE  1 
ATOM   6324  C  CZ  . ARG A 1 825 ? 167.446 140.044 171.250 1.00 83.67  ? 825  ARG A CZ  1 
ATOM   6325  N  NH1 . ARG A 1 825 ? 167.577 141.213 171.855 1.00 83.67  ? 825  ARG A NH1 1 
ATOM   6326  N  NH2 . ARG A 1 825 ? 166.278 139.410 171.307 1.00 83.67  ? 825  ARG A NH2 1 
ATOM   6327  N  N   . VAL A 1 826 ? 170.012 138.042 165.237 1.00 89.03  ? 826  VAL A N   1 
ATOM   6328  C  CA  . VAL A 1 826 ? 169.636 137.948 163.826 1.00 89.03  ? 826  VAL A CA  1 
ATOM   6329  C  C   . VAL A 1 826 ? 168.813 139.171 163.432 1.00 89.03  ? 826  VAL A C   1 
ATOM   6330  O  O   . VAL A 1 826 ? 167.832 139.514 164.109 1.00 89.03  ? 826  VAL A O   1 
ATOM   6331  C  CB  . VAL A 1 826 ? 168.898 136.631 163.526 1.00 89.03  ? 826  VAL A CB  1 
ATOM   6332  C  CG1 . VAL A 1 826 ? 169.847 135.453 163.688 1.00 89.03  ? 826  VAL A CG1 1 
ATOM   6333  C  CG2 . VAL A 1 826 ? 167.705 136.453 164.442 1.00 89.03  ? 826  VAL A CG2 1 
ATOM   6334  N  N   . PRO A 1 827 ? 169.188 139.863 162.359 1.00 87.11  ? 827  PRO A N   1 
ATOM   6335  C  CA  . PRO A 1 827 ? 168.553 141.144 162.037 1.00 87.11  ? 827  PRO A CA  1 
ATOM   6336  C  C   . PRO A 1 827 ? 167.122 140.983 161.548 1.00 87.11  ? 827  PRO A C   1 
ATOM   6337  O  O   . PRO A 1 827 ? 166.703 139.921 161.082 1.00 87.11  ? 827  PRO A O   1 
ATOM   6338  C  CB  . PRO A 1 827 ? 169.448 141.716 160.930 1.00 87.11  ? 827  PRO A CB  1 
ATOM   6339  C  CG  . PRO A 1 827 ? 170.730 140.936 161.019 1.00 87.11  ? 827  PRO A CG  1 
ATOM   6340  C  CD  . PRO A 1 827 ? 170.319 139.573 161.465 1.00 87.11  ? 827  PRO A CD  1 
ATOM   6341  N  N   . PHE A 1 828 ? 166.361 142.068 161.709 1.00 89.58  ? 828  PHE A N   1 
ATOM   6342  C  CA  . PHE A 1 828 ? 165.046 142.267 161.104 1.00 89.58  ? 828  PHE A CA  1 
ATOM   6343  C  C   . PHE A 1 828 ? 163.958 141.407 161.736 1.00 89.58  ? 828  PHE A C   1 
ATOM   6344  O  O   . PHE A 1 828 ? 162.775 141.574 161.421 1.00 89.58  ? 828  PHE A O   1 
ATOM   6345  C  CB  . PHE A 1 828 ? 165.105 142.007 159.595 1.00 89.58  ? 828  PHE A CB  1 
ATOM   6346  C  CG  . PHE A 1 828 ? 165.903 143.027 158.835 1.00 89.58  ? 828  PHE A CG  1 
ATOM   6347  C  CD1 . PHE A 1 828 ? 165.351 144.255 158.513 1.00 89.58  ? 828  PHE A CD1 1 
ATOM   6348  C  CD2 . PHE A 1 828 ? 167.202 142.758 158.440 1.00 89.58  ? 828  PHE A CD2 1 
ATOM   6349  C  CE1 . PHE A 1 828 ? 166.080 145.197 157.812 1.00 89.58  ? 828  PHE A CE1 1 
ATOM   6350  C  CE2 . PHE A 1 828 ? 167.937 143.696 157.740 1.00 89.58  ? 828  PHE A CE2 1 
ATOM   6351  C  CZ  . PHE A 1 828 ? 167.375 144.917 157.425 1.00 89.58  ? 828  PHE A CZ  1 
ATOM   6352  N  N   . ILE A 1 829 ? 164.333 140.490 162.629 1.00 93.68  ? 829  ILE A N   1 
ATOM   6353  C  CA  . ILE A 1 829 ? 163.374 139.700 163.388 1.00 93.68  ? 829  ILE A CA  1 
ATOM   6354  C  C   . ILE A 1 829 ? 163.667 139.731 164.882 1.00 93.68  ? 829  ILE A C   1 
ATOM   6355  O  O   . ILE A 1 829 ? 162.757 139.936 165.692 1.00 93.68  ? 829  ILE A O   1 
ATOM   6356  C  CB  . ILE A 1 829 ? 163.305 138.243 162.876 1.00 93.68  ? 829  ILE A CB  1 
ATOM   6357  C  CG1 . ILE A 1 829 ? 164.703 137.645 162.714 1.00 93.68  ? 829  ILE A CG1 1 
ATOM   6358  C  CG2 . ILE A 1 829 ? 162.536 138.173 161.563 1.00 93.68  ? 829  ILE A CG2 1 
ATOM   6359  C  CD1 . ILE A 1 829 ? 164.691 136.172 162.369 1.00 93.68  ? 829  ILE A CD1 1 
ATOM   6360  N  N   . GLN A 1 830 ? 164.927 139.534 165.271 1.00 89.90  ? 830  GLN A N   1 
ATOM   6361  C  CA  . GLN A 1 830 ? 165.306 139.560 166.676 1.00 89.90  ? 830  GLN A CA  1 
ATOM   6362  C  C   . GLN A 1 830 ? 165.890 140.896 167.112 1.00 89.90  ? 830  GLN A C   1 
ATOM   6363  O  O   . GLN A 1 830 ? 165.876 141.199 168.310 1.00 89.90  ? 830  GLN A O   1 
ATOM   6364  C  CB  . GLN A 1 830 ? 166.317 138.445 166.971 1.00 89.90  ? 830  GLN A CB  1 
ATOM   6365  C  CG  . GLN A 1 830 ? 166.349 137.995 168.418 1.00 89.90  ? 830  GLN A CG  1 
ATOM   6366  C  CD  . GLN A 1 830 ? 167.208 136.764 168.628 1.00 89.90  ? 830  GLN A CD  1 
ATOM   6367  O  OE1 . GLN A 1 830 ? 167.804 136.240 167.688 1.00 89.90  ? 830  GLN A OE1 1 
ATOM   6368  N  NE2 . GLN A 1 830 ? 167.273 136.293 169.868 1.00 89.90  ? 830  GLN A NE2 1 
ATOM   6369  N  N   . SER A 1 831 ? 166.398 141.694 166.175 1.00 86.77  ? 831  SER A N   1 
ATOM   6370  C  CA  . SER A 1 831 ? 166.897 143.027 166.475 1.00 86.77  ? 831  SER A CA  1 
ATOM   6371  C  C   . SER A 1 831 ? 166.763 143.883 165.226 1.00 86.77  ? 831  SER A C   1 
ATOM   6372  O  O   . SER A 1 831 ? 167.042 143.420 164.117 1.00 86.77  ? 831  SER A O   1 
ATOM   6373  C  CB  . SER A 1 831 ? 168.357 142.993 166.946 1.00 86.77  ? 831  SER A CB  1 
ATOM   6374  O  OG  . SER A 1 831 ? 169.221 142.576 165.904 1.00 86.77  ? 831  SER A OG  1 
ATOM   6375  N  N   . CYS A 1 832 ? 166.335 145.128 165.411 1.00 79.59  ? 832  CYS A N   1 
ATOM   6376  C  CA  . CYS A 1 832 ? 166.085 146.036 164.304 1.00 79.59  ? 832  CYS A CA  1 
ATOM   6377  C  C   . CYS A 1 832 ? 166.787 147.362 164.551 1.00 79.59  ? 832  CYS A C   1 
ATOM   6378  O  O   . CYS A 1 832 ? 166.990 147.773 165.697 1.00 79.59  ? 832  CYS A O   1 
ATOM   6379  C  CB  . CYS A 1 832 ? 164.583 146.274 164.099 1.00 79.59  ? 832  CYS A CB  1 
ATOM   6380  S  SG  . CYS A 1 832 ? 163.704 144.884 163.351 1.00 79.59  ? 832  CYS A SG  1 
ATOM   6381  N  N   . ALA A 1 833 ? 167.155 148.026 163.462 1.00 68.35  ? 833  ALA A N   1 
ATOM   6382  C  CA  . ALA A 1 833 ? 167.794 149.332 163.537 1.00 68.35  ? 833  ALA A CA  1 
ATOM   6383  C  C   . ALA A 1 833 ? 166.729 150.402 163.772 1.00 68.35  ? 833  ALA A C   1 
ATOM   6384  O  O   . ALA A 1 833 ? 165.551 150.113 164.003 1.00 68.35  ? 833  ALA A O   1 
ATOM   6385  C  CB  . ALA A 1 833 ? 168.605 149.597 162.273 1.00 68.35  ? 833  ALA A CB  1 
ATOM   6386  N  N   . SER A 1 834 ? 167.140 151.664 163.713 1.00 66.95  ? 834  SER A N   1 
ATOM   6387  C  CA  . SER A 1 834 ? 166.244 152.792 163.913 1.00 66.95  ? 834  SER A CA  1 
ATOM   6388  C  C   . SER A 1 834 ? 165.761 153.305 162.565 1.00 66.95  ? 834  SER A C   1 
ATOM   6389  O  O   . SER A 1 834 ? 166.438 153.134 161.547 1.00 66.95  ? 834  SER A O   1 
ATOM   6390  C  CB  . SER A 1 834 ? 166.939 153.914 164.688 1.00 66.95  ? 834  SER A CB  1 
ATOM   6391  O  OG  . SER A 1 834 ? 166.036 154.964 164.986 1.00 66.95  ? 834  SER A OG  1 
ATOM   6392  N  N   . TRP A 1 835 ? 164.583 153.928 162.566 1.00 68.43  ? 835  TRP A N   1 
ATOM   6393  C  CA  . TRP A 1 835 ? 163.936 154.409 161.350 1.00 68.43  ? 835  TRP A CA  1 
ATOM   6394  C  C   . TRP A 1 835 ? 164.825 155.349 160.536 1.00 68.43  ? 835  TRP A C   1 
ATOM   6395  O  O   . TRP A 1 835 ? 164.896 155.195 159.310 1.00 68.43  ? 835  TRP A O   1 
ATOM   6396  C  CB  . TRP A 1 835 ? 162.608 155.094 161.688 1.00 68.43  ? 835  TRP A CB  1 
ATOM   6397  C  CG  . TRP A 1 835 ? 161.510 154.135 162.030 1.00 68.43  ? 835  TRP A CG  1 
ATOM   6398  C  CD1 . TRP A 1 835 ? 161.540 153.161 162.985 1.00 68.43  ? 835  TRP A CD1 1 
ATOM   6399  C  CD2 . TRP A 1 835 ? 160.218 154.059 161.419 1.00 68.43  ? 835  TRP A CD2 1 
ATOM   6400  N  NE1 . TRP A 1 835 ? 160.346 152.483 163.006 1.00 68.43  ? 835  TRP A NE1 1 
ATOM   6401  C  CE2 . TRP A 1 835 ? 159.517 153.015 162.054 1.00 68.43  ? 835  TRP A CE2 1 
ATOM   6402  C  CE3 . TRP A 1 835 ? 159.585 154.773 160.397 1.00 68.43  ? 835  TRP A CE3 1 
ATOM   6403  C  CZ2 . TRP A 1 835 ? 158.215 152.668 161.700 1.00 68.43  ? 835  TRP A CZ2 1 
ATOM   6404  C  CZ3 . TRP A 1 835 ? 158.293 154.426 160.047 1.00 68.43  ? 835  TRP A CZ3 1 
ATOM   6405  C  CH2 . TRP A 1 835 ? 157.623 153.383 160.697 1.00 68.43  ? 835  TRP A CH2 1 
ATOM   6406  N  N   . PRO A 1 836 ? 165.497 156.340 161.144 1.00 66.50  ? 836  PRO A N   1 
ATOM   6407  C  CA  . PRO A 1 836 ? 166.411 157.174 160.341 1.00 66.50  ? 836  PRO A CA  1 
ATOM   6408  C  C   . PRO A 1 836 ? 167.513 156.383 159.654 1.00 66.50  ? 836  PRO A C   1 
ATOM   6409  O  O   . PRO A 1 836 ? 167.857 156.680 158.503 1.00 66.50  ? 836  PRO A O   1 
ATOM   6410  C  CB  . PRO A 1 836 ? 166.968 158.166 161.371 1.00 66.50  ? 836  PRO A CB  1 
ATOM   6411  C  CG  . PRO A 1 836 ? 165.925 158.248 162.410 1.00 66.50  ? 836  PRO A CG  1 
ATOM   6412  C  CD  . PRO A 1 836 ? 165.372 156.862 162.518 1.00 66.50  ? 836  PRO A CD  1 
ATOM   6413  N  N   . LEU A 1 837 ? 168.068 155.369 160.323 1.00 66.10  ? 837  LEU A N   1 
ATOM   6414  C  CA  . LEU A 1 837 ? 169.131 154.581 159.707 1.00 66.10  ? 837  LEU A CA  1 
ATOM   6415  C  C   . LEU A 1 837 ? 168.613 153.803 158.504 1.00 66.10  ? 837  LEU A C   1 
ATOM   6416  O  O   . LEU A 1 837 ? 169.259 153.769 157.451 1.00 66.10  ? 837  LEU A O   1 
ATOM   6417  C  CB  . LEU A 1 837 ? 169.753 153.632 160.731 1.00 66.10  ? 837  LEU A CB  1 
ATOM   6418  C  CG  . LEU A 1 837 ? 170.788 152.673 160.139 1.00 66.10  ? 837  LEU A CG  1 
ATOM   6419  C  CD1 . LEU A 1 837 ? 171.888 153.443 159.423 1.00 66.10  ? 837  LEU A CD1 1 
ATOM   6420  C  CD2 . LEU A 1 837 ? 171.374 151.769 161.207 1.00 66.10  ? 837  LEU A CD2 1 
ATOM   6421  N  N   . MET A 1 838 ? 167.448 153.167 158.644 1.00 70.39  ? 838  MET A N   1 
ATOM   6422  C  CA  . MET A 1 838 ? 166.869 152.436 157.521 1.00 70.39  ? 838  MET A CA  1 
ATOM   6423  C  C   . MET A 1 838 ? 166.526 153.375 156.373 1.00 70.39  ? 838  MET A C   1 
ATOM   6424  O  O   . MET A 1 838 ? 166.745 153.044 155.200 1.00 70.39  ? 838  MET A O   1 
ATOM   6425  C  CB  . MET A 1 838 ? 165.628 151.670 157.980 1.00 70.39  ? 838  MET A CB  1 
ATOM   6426  C  CG  . MET A 1 838 ? 165.913 150.263 158.478 1.00 70.39  ? 838  MET A CG  1 
ATOM   6427  S  SD  . MET A 1 838 ? 164.454 149.472 159.182 1.00 70.39  ? 838  MET A SD  1 
ATOM   6428  C  CE  . MET A 1 838 ? 165.208 148.290 160.296 1.00 70.39  ? 838  MET A CE  1 
ATOM   6429  N  N   . ILE A 1 839 ? 165.987 154.554 156.693 1.00 67.42  ? 839  ILE A N   1 
ATOM   6430  C  CA  . ILE A 1 839 ? 165.639 155.531 155.662 1.00 67.42  ? 839  ILE A CA  1 
ATOM   6431  C  C   . ILE A 1 839 ? 166.886 155.956 154.898 1.00 67.42  ? 839  ILE A C   1 
ATOM   6432  O  O   . ILE A 1 839 ? 166.900 156.002 153.662 1.00 67.42  ? 839  ILE A O   1 
ATOM   6433  C  CB  . ILE A 1 839 ? 164.921 156.739 156.287 1.00 67.42  ? 839  ILE A CB  1 
ATOM   6434  C  CG1 . ILE A 1 839 ? 163.458 156.397 156.577 1.00 67.42  ? 839  ILE A CG1 1 
ATOM   6435  C  CG2 . ILE A 1 839 ? 165.021 157.957 155.383 1.00 67.42  ? 839  ILE A CG2 1 
ATOM   6436  C  CD1 . ILE A 1 839 ? 162.693 157.507 157.263 1.00 67.42  ? 839  ILE A CD1 1 
ATOM   6437  N  N   . MET A 1 840 ? 167.960 156.264 155.631 1.00 65.84  ? 840  MET A N   1 
ATOM   6438  C  CA  . MET A 1 840 ? 169.204 156.668 154.984 1.00 65.84  ? 840  MET A CA  1 
ATOM   6439  C  C   . MET A 1 840 ? 169.783 155.536 154.147 1.00 65.84  ? 840  MET A C   1 
ATOM   6440  O  O   . MET A 1 840 ? 170.282 155.769 153.041 1.00 65.84  ? 840  MET A O   1 
ATOM   6441  C  CB  . MET A 1 840 ? 170.214 157.137 156.031 1.00 65.84  ? 840  MET A CB  1 
ATOM   6442  C  CG  . MET A 1 840 ? 169.881 158.485 156.650 1.00 65.84  ? 840  MET A CG  1 
ATOM   6443  S  SD  . MET A 1 840 ? 169.600 159.778 155.425 1.00 65.84  ? 840  MET A SD  1 
ATOM   6444  C  CE  . MET A 1 840 ? 171.143 159.727 154.517 1.00 65.84  ? 840  MET A CE  1 
ATOM   6445  N  N   . THR A 1 841 ? 169.724 154.304 154.657 1.00 67.33  ? 841  THR A N   1 
ATOM   6446  C  CA  . THR A 1 841 ? 170.219 153.159 153.900 1.00 67.33  ? 841  THR A CA  1 
ATOM   6447  C  C   . THR A 1 841 ? 169.479 153.016 152.577 1.00 67.33  ? 841  THR A C   1 
ATOM   6448  O  O   . THR A 1 841 ? 170.100 152.880 151.515 1.00 67.33  ? 841  THR A O   1 
ATOM   6449  C  CB  . THR A 1 841 ? 170.082 151.884 154.734 1.00 67.33  ? 841  THR A CB  1 
ATOM   6450  O  OG1 . THR A 1 841 ? 170.751 152.055 155.989 1.00 67.33  ? 841  THR A OG1 1 
ATOM   6451  C  CG2 . THR A 1 841 ? 170.676 150.693 154.000 1.00 67.33  ? 841  THR A CG2 1 
ATOM   6452  N  N   . VAL A 1 842 ? 168.146 153.060 152.621 1.00 69.24  ? 842  VAL A N   1 
ATOM   6453  C  CA  . VAL A 1 842 ? 167.356 152.899 151.404 1.00 69.24  ? 842  VAL A CA  1 
ATOM   6454  C  C   . VAL A 1 842 ? 167.620 154.046 150.434 1.00 69.24  ? 842  VAL A C   1 
ATOM   6455  O  O   . VAL A 1 842 ? 167.773 153.834 149.225 1.00 69.24  ? 842  VAL A O   1 
ATOM   6456  C  CB  . VAL A 1 842 ? 165.860 152.776 151.743 1.00 69.24  ? 842  VAL A CB  1 
ATOM   6457  C  CG1 . VAL A 1 842 ? 165.039 152.666 150.471 1.00 69.24  ? 842  VAL A CG1 1 
ATOM   6458  C  CG2 . VAL A 1 842 ? 165.618 151.564 152.627 1.00 69.24  ? 842  VAL A CG2 1 
ATOM   6459  N  N   . ILE A 1 843 ? 167.681 155.278 150.947 1.00 68.73  ? 843  ILE A N   1 
ATOM   6460  C  CA  . ILE A 1 843 ? 167.876 156.437 150.076 1.00 68.73  ? 843  ILE A CA  1 
ATOM   6461  C  C   . ILE A 1 843 ? 169.240 156.375 149.399 1.00 68.73  ? 843  ILE A C   1 
ATOM   6462  O  O   . ILE A 1 843 ? 169.371 156.637 148.198 1.00 68.73  ? 843  ILE A O   1 
ATOM   6463  C  CB  . ILE A 1 843 ? 167.696 157.743 150.870 1.00 68.73  ? 843  ILE A CB  1 
ATOM   6464  C  CG1 . ILE A 1 843 ? 166.218 157.964 151.196 1.00 68.73  ? 843  ILE A CG1 1 
ATOM   6465  C  CG2 . ILE A 1 843 ? 168.256 158.927 150.097 1.00 68.73  ? 843  ILE A CG2 1 
ATOM   6466  C  CD1 . ILE A 1 843 ? 165.954 159.192 152.038 1.00 68.73  ? 843  ILE A CD1 1 
ATOM   6467  N  N   . VAL A 1 844 ? 170.279 156.022 150.160 1.00 69.02  ? 844  VAL A N   1 
ATOM   6468  C  CA  . VAL A 1 844 ? 171.624 155.962 149.594 1.00 69.02  ? 844  VAL A CA  1 
ATOM   6469  C  C   . VAL A 1 844 ? 171.732 154.814 148.598 1.00 69.02  ? 844  VAL A C   1 
ATOM   6470  O  O   . VAL A 1 844 ? 172.401 154.929 147.565 1.00 69.02  ? 844  VAL A O   1 
ATOM   6471  C  CB  . VAL A 1 844 ? 172.672 155.855 150.715 1.00 69.02  ? 844  VAL A CB  1 
ATOM   6472  C  CG1 . VAL A 1 844 ? 174.038 155.510 150.145 1.00 69.02  ? 844  VAL A CG1 1 
ATOM   6473  C  CG2 . VAL A 1 844 ? 172.738 157.165 151.477 1.00 69.02  ? 844  VAL A CG2 1 
ATOM   6474  N  N   . MET A 1 845 ? 171.068 153.691 148.885 1.00 73.64  ? 845  MET A N   1 
ATOM   6475  C  CA  . MET A 1 845 ? 171.042 152.592 147.926 1.00 73.64  ? 845  MET A CA  1 
ATOM   6476  C  C   . MET A 1 845 ? 170.379 153.024 146.624 1.00 73.64  ? 845  MET A C   1 
ATOM   6477  O  O   . MET A 1 845 ? 170.863 152.711 145.529 1.00 73.64  ? 845  MET A O   1 
ATOM   6478  C  CB  . MET A 1 845 ? 170.317 151.391 148.531 1.00 73.64  ? 845  MET A CB  1 
ATOM   6479  C  CG  . MET A 1 845 ? 171.205 150.480 149.357 1.00 73.64  ? 845  MET A CG  1 
ATOM   6480  S  SD  . MET A 1 845 ? 170.254 149.383 150.424 1.00 73.64  ? 845  MET A SD  1 
ATOM   6481  C  CE  . MET A 1 845 ? 169.567 148.250 149.221 1.00 73.64  ? 845  MET A CE  1 
ATOM   6482  N  N   . ILE A 1 846 ? 169.267 153.758 146.727 1.00 72.06  ? 846  ILE A N   1 
ATOM   6483  C  CA  . ILE A 1 846 ? 168.572 154.243 145.537 1.00 72.06  ? 846  ILE A CA  1 
ATOM   6484  C  C   . ILE A 1 846 ? 169.458 155.202 144.753 1.00 72.06  ? 846  ILE A C   1 
ATOM   6485  O  O   . ILE A 1 846 ? 169.525 155.144 143.519 1.00 72.06  ? 846  ILE A O   1 
ATOM   6486  C  CB  . ILE A 1 846 ? 167.235 154.899 145.935 1.00 72.06  ? 846  ILE A CB  1 
ATOM   6487  C  CG1 . ILE A 1 846 ? 166.213 153.830 146.324 1.00 72.06  ? 846  ILE A CG1 1 
ATOM   6488  C  CG2 . ILE A 1 846 ? 166.698 155.764 144.805 1.00 72.06  ? 846  ILE A CG2 1 
ATOM   6489  C  CD1 . ILE A 1 846 ? 164.849 154.386 146.671 1.00 72.06  ? 846  ILE A CD1 1 
ATOM   6490  N  N   . VAL A 1 847 ? 170.150 156.100 145.457 1.00 72.77  ? 847  VAL A N   1 
ATOM   6491  C  CA  . VAL A 1 847 ? 171.032 157.056 144.791 1.00 72.77  ? 847  VAL A CA  1 
ATOM   6492  C  C   . VAL A 1 847 ? 172.166 156.330 144.076 1.00 72.77  ? 847  VAL A C   1 
ATOM   6493  O  O   . VAL A 1 847 ? 172.510 156.657 142.933 1.00 72.77  ? 847  VAL A O   1 
ATOM   6494  C  CB  . VAL A 1 847 ? 171.566 158.086 145.805 1.00 72.77  ? 847  VAL A CB  1 
ATOM   6495  C  CG1 . VAL A 1 847 ? 172.718 158.876 145.208 1.00 72.77  ? 847  VAL A CG1 1 
ATOM   6496  C  CG2 . VAL A 1 847 ? 170.451 159.020 146.243 1.00 72.77  ? 847  VAL A CG2 1 
ATOM   6497  N  N   . GLY A 1 848 ? 172.761 155.334 144.734 1.00 75.35  ? 848  GLY A N   1 
ATOM   6498  C  CA  . GLY A 1 848 ? 173.826 154.575 144.100 1.00 75.35  ? 848  GLY A CA  1 
ATOM   6499  C  C   . GLY A 1 848 ? 173.350 153.803 142.886 1.00 75.35  ? 848  GLY A C   1 
ATOM   6500  O  O   . GLY A 1 848 ? 174.062 153.703 141.884 1.00 75.35  ? 848  GLY A O   1 
ATOM   6501  N  N   . ILE A 1 849 ? 172.143 153.238 142.961 1.00 77.54  ? 849  ILE A N   1 
ATOM   6502  C  CA  . ILE A 1 849 ? 171.583 152.534 141.812 1.00 77.54  ? 849  ILE A CA  1 
ATOM   6503  C  C   . ILE A 1 849 ? 171.336 153.499 140.658 1.00 77.54  ? 849  ILE A C   1 
ATOM   6504  O  O   . ILE A 1 849 ? 171.643 153.195 139.500 1.00 77.54  ? 849  ILE A O   1 
ATOM   6505  C  CB  . ILE A 1 849 ? 170.296 151.793 142.217 1.00 77.54  ? 849  ILE A CB  1 
ATOM   6506  C  CG1 . ILE A 1 849 ? 170.628 150.577 143.082 1.00 77.54  ? 849  ILE A CG1 1 
ATOM   6507  C  CG2 . ILE A 1 849 ? 169.507 151.371 140.987 1.00 77.54  ? 849  ILE A CG2 1 
ATOM   6508  C  CD1 . ILE A 1 849 ? 169.411 149.891 143.662 1.00 77.54  ? 849  ILE A CD1 1 
ATOM   6509  N  N   . ALA A 1 850 ? 170.788 154.678 140.954 1.00 80.48  ? 850  ALA A N   1 
ATOM   6510  C  CA  . ALA A 1 850 ? 170.406 155.623 139.913 1.00 80.48  ? 850  ALA A CA  1 
ATOM   6511  C  C   . ALA A 1 850 ? 171.573 156.439 139.374 1.00 80.48  ? 850  ALA A C   1 
ATOM   6512  O  O   . ALA A 1 850 ? 171.415 157.094 138.338 1.00 80.48  ? 850  ALA A O   1 
ATOM   6513  C  CB  . ALA A 1 850 ? 169.324 156.569 140.438 1.00 80.48  ? 850  ALA A CB  1 
ATOM   6514  N  N   . LEU A 1 851 ? 172.725 156.430 140.044 1.00 83.59  ? 851  LEU A N   1 
ATOM   6515  C  CA  . LEU A 1 851 ? 173.862 157.210 139.558 1.00 83.59  ? 851  LEU A CA  1 
ATOM   6516  C  C   . LEU A 1 851 ? 174.337 156.777 138.175 1.00 83.59  ? 851  LEU A C   1 
ATOM   6517  O  O   . LEU A 1 851 ? 174.550 157.657 137.322 1.00 83.59  ? 851  LEU A O   1 
ATOM   6518  C  CB  . LEU A 1 851 ? 175.000 157.162 140.583 1.00 83.59  ? 851  LEU A CB  1 
ATOM   6519  C  CG  . LEU A 1 851 ? 175.998 158.319 140.505 1.00 83.59  ? 851  LEU A CG  1 
ATOM   6520  C  CD1 . LEU A 1 851 ? 175.334 159.629 140.899 1.00 83.59  ? 851  LEU A CD1 1 
ATOM   6521  C  CD2 . LEU A 1 851 ? 177.209 158.046 141.380 1.00 83.59  ? 851  LEU A CD2 1 
ATOM   6522  N  N   . PRO A 1 852 ? 174.537 155.487 137.878 1.00 89.35  ? 852  PRO A N   1 
ATOM   6523  C  CA  . PRO A 1 852 ? 174.912 155.114 136.503 1.00 89.35  ? 852  PRO A CA  1 
ATOM   6524  C  C   . PRO A 1 852 ? 173.873 155.490 135.460 1.00 89.35  ? 852  PRO A C   1 
ATOM   6525  O  O   . PRO A 1 852 ? 174.242 155.763 134.312 1.00 89.35  ? 852  PRO A O   1 
ATOM   6526  C  CB  . PRO A 1 852 ? 175.095 153.592 136.587 1.00 89.35  ? 852  PRO A CB  1 
ATOM   6527  C  CG  . PRO A 1 852 ? 175.393 153.332 138.016 1.00 89.35  ? 852  PRO A CG  1 
ATOM   6528  C  CD  . PRO A 1 852 ? 174.551 154.312 138.768 1.00 89.35  ? 852  PRO A CD  1 
ATOM   6529  N  N   . PHE A 1 853 ? 172.589 155.505 135.814 1.00 88.92  ? 853  PHE A N   1 
ATOM   6530  C  CA  . PHE A 1 853 ? 171.539 155.863 134.871 1.00 88.92  ? 853  PHE A CA  1 
ATOM   6531  C  C   . PHE A 1 853 ? 171.262 157.359 134.824 1.00 88.92  ? 853  PHE A C   1 
ATOM   6532  O  O   . PHE A 1 853 ? 170.509 157.806 133.952 1.00 88.92  ? 853  PHE A O   1 
ATOM   6533  C  CB  . PHE A 1 853 ? 170.244 155.120 135.215 1.00 88.92  ? 853  PHE A CB  1 
ATOM   6534  C  CG  . PHE A 1 853 ? 170.384 153.625 135.214 1.00 88.92  ? 853  PHE A CG  1 
ATOM   6535  C  CD1 . PHE A 1 853 ? 171.197 152.993 134.289 1.00 88.92  ? 853  PHE A CD1 1 
ATOM   6536  C  CD2 . PHE A 1 853 ? 169.700 152.852 136.136 1.00 88.92  ? 853  PHE A CD2 1 
ATOM   6537  C  CE1 . PHE A 1 853 ? 171.327 151.618 134.287 1.00 88.92  ? 853  PHE A CE1 1 
ATOM   6538  C  CE2 . PHE A 1 853 ? 169.825 151.477 136.138 1.00 88.92  ? 853  PHE A CE2 1 
ATOM   6539  C  CZ  . PHE A 1 853 ? 170.640 150.859 135.213 1.00 88.92  ? 853  PHE A CZ  1 
ATOM   6540  N  N   . SER A 1 854 ? 171.843 158.136 135.731 1.00 91.10  ? 854  SER A N   1 
ATOM   6541  C  CA  . SER A 1 854 ? 171.632 159.572 135.754 1.00 91.10  ? 854  SER A CA  1 
ATOM   6542  C  C   . SER A 1 854 ? 172.443 160.250 134.655 1.00 91.10  ? 854  SER A C   1 
ATOM   6543  O  O   . SER A 1 854 ? 173.454 159.714 134.195 1.00 91.10  ? 854  SER A O   1 
ATOM   6544  C  CB  . SER A 1 854 ? 172.021 160.135 137.117 1.00 91.10  ? 854  SER A CB  1 
ATOM   6545  O  OG  . SER A 1 854 ? 173.421 160.333 137.204 1.00 91.10  ? 854  SER A OG  1 
ATOM   6546  N  N   . PRO A 1 855 ? 172.013 161.433 134.207 1.00 94.61  ? 855  PRO A N   1 
ATOM   6547  C  CA  . PRO A 1 855 ? 172.808 162.167 133.208 1.00 94.61  ? 855  PRO A CA  1 
ATOM   6548  C  C   . PRO A 1 855 ? 174.195 162.545 133.696 1.00 94.61  ? 855  PRO A C   1 
ATOM   6549  O  O   . PRO A 1 855 ? 175.092 162.748 132.868 1.00 94.61  ? 855  PRO A O   1 
ATOM   6550  C  CB  . PRO A 1 855 ? 171.956 163.413 132.923 1.00 94.61  ? 855  PRO A CB  1 
ATOM   6551  C  CG  . PRO A 1 855 ? 171.016 163.520 134.083 1.00 94.61  ? 855  PRO A CG  1 
ATOM   6552  C  CD  . PRO A 1 855 ? 170.746 162.115 134.513 1.00 94.61  ? 855  PRO A CD  1 
ATOM   6553  N  N   . LEU A 1 856 ? 174.401 162.648 135.011 1.00 92.54  ? 856  LEU A N   1 
ATOM   6554  C  CA  . LEU A 1 856 ? 175.724 162.957 135.541 1.00 92.54  ? 856  LEU A CA  1 
ATOM   6555  C  C   . LEU A 1 856 ? 176.720 161.828 135.314 1.00 92.54  ? 856  LEU A C   1 
ATOM   6556  O  O   . LEU A 1 856 ? 177.931 162.065 135.392 1.00 92.54  ? 856  LEU A O   1 
ATOM   6557  C  CB  . LEU A 1 856 ? 175.630 163.268 137.035 1.00 92.54  ? 856  LEU A CB  1 
ATOM   6558  C  CG  . LEU A 1 856 ? 175.241 164.696 137.421 1.00 92.54  ? 856  LEU A CG  1 
ATOM   6559  C  CD1 . LEU A 1 856 ? 175.107 164.822 138.930 1.00 92.54  ? 856  LEU A CD1 1 
ATOM   6560  C  CD2 . LEU A 1 856 ? 176.261 165.688 136.887 1.00 92.54  ? 856  LEU A CD2 1 
ATOM   6561  N  N   . ALA A 1 857 ? 176.238 160.614 135.031 1.00 90.56  ? 857  ALA A N   1 
ATOM   6562  C  CA  . ALA A 1 857 ? 177.130 159.468 134.886 1.00 90.56  ? 857  ALA A CA  1 
ATOM   6563  C  C   . ALA A 1 857 ? 178.149 159.691 133.777 1.00 90.56  ? 857  ALA A C   1 
ATOM   6564  O  O   . ALA A 1 857 ? 179.296 159.240 133.878 1.00 90.56  ? 857  ALA A O   1 
ATOM   6565  C  CB  . ALA A 1 857 ? 176.316 158.203 134.618 1.00 90.56  ? 857  ALA A CB  1 
ATOM   6566  N  N   . SER A 1 858 ? 177.748 160.382 132.708 1.00 90.07  ? 858  SER A N   1 
ATOM   6567  C  CA  . SER A 1 858 ? 178.690 160.693 131.638 1.00 90.07  ? 858  SER A CA  1 
ATOM   6568  C  C   . SER A 1 858 ? 179.822 161.575 132.146 1.00 90.07  ? 858  SER A C   1 
ATOM   6569  O  O   . SER A 1 858 ? 180.987 161.375 131.782 1.00 90.07  ? 858  SER A O   1 
ATOM   6570  C  CB  . SER A 1 858 ? 177.960 161.367 130.477 1.00 90.07  ? 858  SER A CB  1 
ATOM   6571  O  OG  . SER A 1 858 ? 177.397 162.603 130.881 1.00 90.07  ? 858  SER A OG  1 
ATOM   6572  N  N   . TYR A 1 859 ? 179.499 162.558 132.988 1.00 91.31  ? 859  TYR A N   1 
ATOM   6573  C  CA  . TYR A 1 859 ? 180.537 163.420 133.544 1.00 91.31  ? 859  TYR A CA  1 
ATOM   6574  C  C   . TYR A 1 859 ? 181.397 162.669 134.553 1.00 91.31  ? 859  TYR A C   1 
ATOM   6575  O  O   . TYR A 1 859 ? 182.600 162.930 134.669 1.00 91.31  ? 859  TYR A O   1 
ATOM   6576  C  CB  . TYR A 1 859 ? 179.905 164.656 134.183 1.00 91.31  ? 859  TYR A CB  1 
ATOM   6577  C  CG  . TYR A 1 859 ? 179.462 165.695 133.179 1.00 91.31  ? 859  TYR A CG  1 
ATOM   6578  C  CD1 . TYR A 1 859 ? 180.215 165.952 132.040 1.00 91.31  ? 859  TYR A CD1 1 
ATOM   6579  C  CD2 . TYR A 1 859 ? 178.293 166.420 133.368 1.00 91.31  ? 859  TYR A CD2 1 
ATOM   6580  C  CE1 . TYR A 1 859 ? 179.817 166.901 131.119 1.00 91.31  ? 859  TYR A CE1 1 
ATOM   6581  C  CE2 . TYR A 1 859 ? 177.887 167.371 132.452 1.00 91.31  ? 859  TYR A CE2 1 
ATOM   6582  C  CZ  . TYR A 1 859 ? 178.653 167.607 131.330 1.00 91.31  ? 859  TYR A CZ  1 
ATOM   6583  O  OH  . TYR A 1 859 ? 178.254 168.553 130.414 1.00 91.31  ? 859  TYR A OH  1 
ATOM   6584  N  N   . LEU A 1 860 ? 180.800 161.735 135.291 1.00 86.70  ? 860  LEU A N   1 
ATOM   6585  C  CA  . LEU A 1 860 ? 181.517 160.937 136.274 1.00 86.70  ? 860  LEU A CA  1 
ATOM   6586  C  C   . LEU A 1 860 ? 182.160 159.695 135.670 1.00 86.70  ? 860  LEU A C   1 
ATOM   6587  O  O   . LEU A 1 860 ? 182.618 158.825 136.419 1.00 86.70  ? 860  LEU A O   1 
ATOM   6588  C  CB  . LEU A 1 860 ? 180.575 160.532 137.412 1.00 86.70  ? 860  LEU A CB  1 
ATOM   6589  C  CG  . LEU A 1 860 ? 179.810 161.670 138.091 1.00 86.70  ? 860  LEU A CG  1 
ATOM   6590  C  CD1 . LEU A 1 860 ? 178.709 161.119 138.981 1.00 86.70  ? 860  LEU A CD1 1 
ATOM   6591  C  CD2 . LEU A 1 860 ? 180.756 162.553 138.888 1.00 86.70  ? 860  LEU A CD2 1 
ATOM   6592  N  N   . GLN A 1 861 ? 182.201 159.597 134.339 1.00 88.71  ? 861  GLN A N   1 
ATOM   6593  C  CA  . GLN A 1 861 ? 182.787 158.451 133.640 1.00 88.71  ? 861  GLN A CA  1 
ATOM   6594  C  C   . GLN A 1 861 ? 182.112 157.144 134.049 1.00 88.71  ? 861  GLN A C   1 
ATOM   6595  O  O   . GLN A 1 861 ? 182.769 156.124 134.266 1.00 88.71  ? 861  GLN A O   1 
ATOM   6596  C  CB  . GLN A 1 861 ? 184.300 158.380 133.865 1.00 88.71  ? 861  GLN A CB  1 
ATOM   6597  C  CG  . GLN A 1 861 ? 185.064 159.571 133.310 1.00 88.71  ? 861  GLN A CG  1 
ATOM   6598  C  CD  . GLN A 1 861 ? 186.564 159.351 133.305 1.00 88.71  ? 861  GLN A CD  1 
ATOM   6599  O  OE1 . GLN A 1 861 ? 187.112 158.744 132.385 1.00 88.71  ? 861  GLN A OE1 1 
ATOM   6600  N  NE2 . GLN A 1 861 ? 187.238 159.847 134.336 1.00 88.71  ? 861  GLN A NE2 1 
ATOM   6601  N  N   . LEU A 1 862 ? 180.786 157.175 134.152 1.00 87.26  ? 862  LEU A N   1 
ATOM   6602  C  CA  . LEU A 1 862 ? 179.986 156.013 134.513 1.00 87.26  ? 862  LEU A CA  1 
ATOM   6603  C  C   . LEU A 1 862 ? 179.098 155.633 133.336 1.00 87.26  ? 862  LEU A C   1 
ATOM   6604  O  O   . LEU A 1 862 ? 178.488 156.504 132.707 1.00 87.26  ? 862  LEU A O   1 
ATOM   6605  C  CB  . LEU A 1 862 ? 179.134 156.294 135.754 1.00 87.26  ? 862  LEU A CB  1 
ATOM   6606  C  CG  . LEU A 1 862 ? 179.856 156.320 137.102 1.00 87.26  ? 862  LEU A CG  1 
ATOM   6607  C  CD1 . LEU A 1 862 ? 178.898 156.729 138.208 1.00 87.26  ? 862  LEU A CD1 1 
ATOM   6608  C  CD2 . LEU A 1 862 ? 180.471 154.966 137.403 1.00 87.26  ? 862  LEU A CD2 1 
ATOM   6609  N  N   . GLN A 1 863 ? 179.028 154.338 133.044 1.00 92.19  ? 863  GLN A N   1 
ATOM   6610  C  CA  . GLN A 1 863 ? 178.250 153.823 131.926 1.00 92.19  ? 863  GLN A CA  1 
ATOM   6611  C  C   . GLN A 1 863 ? 177.002 153.119 132.444 1.00 92.19  ? 863  GLN A C   1 
ATOM   6612  O  O   . GLN A 1 863 ? 177.022 152.509 133.516 1.00 92.19  ? 863  GLN A O   1 
ATOM   6613  C  CB  . GLN A 1 863 ? 179.093 152.863 131.080 1.00 92.19  ? 863  GLN A CB  1 
ATOM   6614  C  CG  . GLN A 1 863 ? 178.333 152.142 129.977 1.00 92.19  ? 863  GLN A CG  1 
ATOM   6615  C  CD  . GLN A 1 863 ? 179.203 151.161 129.217 1.00 92.19  ? 863  GLN A CD  1 
ATOM   6616  O  OE1 . GLN A 1 863 ? 180.388 151.008 129.511 1.00 92.19  ? 863  GLN A OE1 1 
ATOM   6617  N  NE2 . GLN A 1 863 ? 178.617 150.489 128.233 1.00 92.19  ? 863  GLN A NE2 1 
ATOM   6618  N  N   . ALA A 1 864 ? 175.916 153.218 131.679 1.00 94.09  ? 864  ALA A N   1 
ATOM   6619  C  CA  . ALA A 1 864 ? 174.658 152.599 132.075 1.00 94.09  ? 864  ALA A CA  1 
ATOM   6620  C  C   . ALA A 1 864 ? 174.803 151.084 132.160 1.00 94.09  ? 864  ALA A C   1 
ATOM   6621  O  O   . ALA A 1 864 ? 175.565 150.470 131.408 1.00 94.09  ? 864  ALA A O   1 
ATOM   6622  C  CB  . ALA A 1 864 ? 173.552 152.968 131.087 1.00 94.09  ? 864  ALA A CB  1 
ATOM   6623  N  N   . LEU A 1 865 ? 174.062 150.482 133.093 1.00 94.85  ? 865  LEU A N   1 
ATOM   6624  C  CA  . LEU A 1 865 ? 174.130 149.055 133.385 1.00 94.85  ? 865  LEU A CA  1 
ATOM   6625  C  C   . LEU A 1 865 ? 172.992 148.318 132.699 1.00 94.85  ? 865  LEU A C   1 
ATOM   6626  O  O   . LEU A 1 865 ? 171.847 148.796 132.725 1.00 94.85  ? 865  LEU A O   1 
ATOM   6627  C  CB  . LEU A 1 865 ? 174.064 148.816 134.891 1.00 94.85  ? 865  LEU A CB  1 
ATOM   6628  C  CG  . LEU A 1 865 ? 175.380 148.772 135.672 1.00 94.85  ? 865  LEU A CG  1 
ATOM   6629  C  CD1 . LEU A 1 865 ? 176.183 150.047 135.484 1.00 94.85  ? 865  LEU A CD1 1 
ATOM   6630  C  CD2 . LEU A 1 865 ? 175.102 148.536 137.146 1.00 94.85  ? 865  LEU A CD2 1 
ATOM   6631  N  N   . PRO A 1 866 ? 173.257 147.171 132.079 1.00 99.83  ? 866  PRO A N   1 
ATOM   6632  C  CA  . PRO A 1 866 ? 172.174 146.393 131.470 1.00 99.83  ? 866  PRO A CA  1 
ATOM   6633  C  C   . PRO A 1 866 ? 171.252 145.800 132.523 1.00 99.83  ? 866  PRO A C   1 
ATOM   6634  O  O   . PRO A 1 866 ? 171.637 145.589 133.676 1.00 99.83  ? 866  PRO A O   1 
ATOM   6635  C  CB  . PRO A 1 866 ? 172.914 145.296 130.698 1.00 99.83  ? 866  PRO A CB  1 
ATOM   6636  C  CG  . PRO A 1 866 ? 174.217 145.157 131.409 1.00 99.83  ? 866  PRO A CG  1 
ATOM   6637  C  CD  . PRO A 1 866 ? 174.572 146.532 131.897 1.00 99.83  ? 866  PRO A CD  1 
ATOM   6638  N  N   . LEU A 1 867 ? 170.011 145.531 132.108 1.00 98.06  ? 867  LEU A N   1 
ATOM   6639  C  CA  . LEU A 1 867 ? 169.010 145.007 133.030 1.00 98.06  ? 867  LEU A CA  1 
ATOM   6640  C  C   . LEU A 1 867 ? 169.344 143.607 133.530 1.00 98.06  ? 867  LEU A C   1 
ATOM   6641  O  O   . LEU A 1 867 ? 168.852 143.210 134.591 1.00 98.06  ? 867  LEU A O   1 
ATOM   6642  C  CB  . LEU A 1 867 ? 167.632 145.002 132.366 1.00 98.06  ? 867  LEU A CB  1 
ATOM   6643  C  CG  . LEU A 1 867 ? 166.772 146.251 132.570 1.00 98.06  ? 867  LEU A CG  1 
ATOM   6644  C  CD1 . LEU A 1 867 ? 167.264 147.401 131.703 1.00 98.06  ? 867  LEU A CD1 1 
ATOM   6645  C  CD2 . LEU A 1 867 ? 165.309 145.947 132.286 1.00 98.06  ? 867  LEU A CD2 1 
ATOM   6646  N  N   . SER A 1 868 ? 170.164 142.852 132.797 1.00 98.38  ? 868  SER A N   1 
ATOM   6647  C  CA  . SER A 1 868 ? 170.553 141.520 133.244 1.00 98.38  ? 868  SER A CA  1 
ATOM   6648  C  C   . SER A 1 868 ? 171.499 141.553 134.436 1.00 98.38  ? 868  SER A C   1 
ATOM   6649  O  O   . SER A 1 868 ? 171.691 140.517 135.081 1.00 98.38  ? 868  SER A O   1 
ATOM   6650  C  CB  . SER A 1 868 ? 171.202 140.749 132.093 1.00 98.38  ? 868  SER A CB  1 
ATOM   6651  O  OG  . SER A 1 868 ? 172.260 141.494 131.515 1.00 98.38  ? 868  SER A OG  1 
ATOM   6652  N  N   . TYR A 1 869 ? 172.093 142.709 134.738 1.00 98.30  ? 869  TYR A N   1 
ATOM   6653  C  CA  . TYR A 1 869 ? 173.043 142.793 135.842 1.00 98.30  ? 869  TYR A CA  1 
ATOM   6654  C  C   . TYR A 1 869 ? 172.329 142.892 137.184 1.00 98.30  ? 869  TYR A C   1 
ATOM   6655  O  O   . TYR A 1 869 ? 172.914 142.585 138.230 1.00 98.30  ? 869  TYR A O   1 
ATOM   6656  C  CB  . TYR A 1 869 ? 173.968 143.991 135.631 1.00 98.30  ? 869  TYR A CB  1 
ATOM   6657  C  CG  . TYR A 1 869 ? 175.065 144.125 136.659 1.00 98.30  ? 869  TYR A CG  1 
ATOM   6658  C  CD1 . TYR A 1 869 ? 176.171 143.287 136.631 1.00 98.30  ? 869  TYR A CD1 1 
ATOM   6659  C  CD2 . TYR A 1 869 ? 175.004 145.096 137.648 1.00 98.30  ? 869  TYR A CD2 1 
ATOM   6660  C  CE1 . TYR A 1 869 ? 177.178 143.405 137.562 1.00 98.30  ? 869  TYR A CE1 1 
ATOM   6661  C  CE2 . TYR A 1 869 ? 176.010 145.224 138.583 1.00 98.30  ? 869  TYR A CE2 1 
ATOM   6662  C  CZ  . TYR A 1 869 ? 177.095 144.375 138.534 1.00 98.30  ? 869  TYR A CZ  1 
ATOM   6663  O  OH  . TYR A 1 869 ? 178.105 144.491 139.458 1.00 98.30  ? 869  TYR A OH  1 
ATOM   6664  N  N   . PHE A 1 870 ? 171.073 143.339 137.175 1.00 95.60  ? 870  PHE A N   1 
ATOM   6665  C  CA  . PHE A 1 870 ? 170.332 143.494 138.423 1.00 95.60  ? 870  PHE A CA  1 
ATOM   6666  C  C   . PHE A 1 870 ? 170.094 142.178 139.159 1.00 95.60  ? 870  PHE A C   1 
ATOM   6667  O  O   . PHE A 1 870 ? 170.302 142.149 140.385 1.00 95.60  ? 870  PHE A O   1 
ATOM   6668  C  CB  . PHE A 1 870 ? 169.007 144.217 138.147 1.00 95.60  ? 870  PHE A CB  1 
ATOM   6669  C  CG  . PHE A 1 870 ? 169.139 145.709 138.050 1.00 95.60  ? 870  PHE A CG  1 
ATOM   6670  C  CD1 . PHE A 1 870 ? 169.728 146.293 136.941 1.00 95.60  ? 870  PHE A CD1 1 
ATOM   6671  C  CD2 . PHE A 1 870 ? 168.666 146.528 139.061 1.00 95.60  ? 870  PHE A CD2 1 
ATOM   6672  C  CE1 . PHE A 1 870 ? 169.850 147.667 136.845 1.00 95.60  ? 870  PHE A CE1 1 
ATOM   6673  C  CE2 . PHE A 1 870 ? 168.784 147.902 138.970 1.00 95.60  ? 870  PHE A CE2 1 
ATOM   6674  C  CZ  . PHE A 1 870 ? 169.377 148.472 137.861 1.00 95.60  ? 870  PHE A CZ  1 
ATOM   6675  N  N   . PRO A 1 871 ? 169.634 141.091 138.519 1.00 95.92  ? 871  PRO A N   1 
ATOM   6676  C  CA  . PRO A 1 871 ? 169.510 139.826 139.267 1.00 95.92  ? 871  PRO A CA  1 
ATOM   6677  C  C   . PRO A 1 871 ? 170.828 139.338 139.835 1.00 95.92  ? 871  PRO A C   1 
ATOM   6678  O  O   . PRO A 1 871 ? 170.864 138.820 140.959 1.00 95.92  ? 871  PRO A O   1 
ATOM   6679  C  CB  . PRO A 1 871 ? 168.947 138.855 138.220 1.00 95.92  ? 871  PRO A CB  1 
ATOM   6680  C  CG  . PRO A 1 871 ? 168.270 139.722 137.226 1.00 95.92  ? 871  PRO A CG  1 
ATOM   6681  C  CD  . PRO A 1 871 ? 169.109 140.958 137.148 1.00 95.92  ? 871  PRO A CD  1 
ATOM   6682  N  N   . TRP A 1 872 ? 171.922 139.497 139.087 1.00 95.15  ? 872  TRP A N   1 
ATOM   6683  C  CA  . TRP A 1 872 ? 173.226 139.085 139.592 1.00 95.15  ? 872  TRP A CA  1 
ATOM   6684  C  C   . TRP A 1 872 ? 173.628 139.910 140.806 1.00 95.15  ? 872  TRP A C   1 
ATOM   6685  O  O   . TRP A 1 872 ? 174.149 139.371 141.789 1.00 95.15  ? 872  TRP A O   1 
ATOM   6686  C  CB  . TRP A 1 872 ? 174.276 139.203 138.489 1.00 95.15  ? 872  TRP A CB  1 
ATOM   6687  C  CG  . TRP A 1 872 ? 174.159 138.144 137.440 1.00 95.15  ? 872  TRP A CG  1 
ATOM   6688  C  CD1 . TRP A 1 872 ? 173.560 138.262 136.220 1.00 95.15  ? 872  TRP A CD1 1 
ATOM   6689  C  CD2 . TRP A 1 872 ? 174.645 136.800 137.520 1.00 95.15  ? 872  TRP A CD2 1 
ATOM   6690  N  NE1 . TRP A 1 872 ? 173.648 137.076 135.533 1.00 95.15  ? 872  TRP A NE1 1 
ATOM   6691  C  CE2 . TRP A 1 872 ? 174.309 136.162 136.310 1.00 95.15  ? 872  TRP A CE2 1 
ATOM   6692  C  CE3 . TRP A 1 872 ? 175.333 136.075 138.498 1.00 95.15  ? 872  TRP A CE3 1 
ATOM   6693  C  CZ2 . TRP A 1 872 ? 174.638 134.833 136.051 1.00 95.15  ? 872  TRP A CZ2 1 
ATOM   6694  C  CZ3 . TRP A 1 872 ? 175.659 134.757 138.238 1.00 95.15  ? 872  TRP A CZ3 1 
ATOM   6695  C  CH2 . TRP A 1 872 ? 175.312 134.150 137.026 1.00 95.15  ? 872  TRP A CH2 1 
ATOM   6696  N  N   . LEU A 1 873 ? 173.385 141.221 140.759 1.00 91.66  ? 873  LEU A N   1 
ATOM   6697  C  CA  . LEU A 1 873 ? 173.699 142.077 141.898 1.00 91.66  ? 873  LEU A CA  1 
ATOM   6698  C  C   . LEU A 1 873 ? 172.867 141.694 143.115 1.00 91.66  ? 873  LEU A C   1 
ATOM   6699  O  O   . LEU A 1 873 ? 173.374 141.653 144.243 1.00 91.66  ? 873  LEU A O   1 
ATOM   6700  C  CB  . LEU A 1 873 ? 173.475 143.542 141.522 1.00 91.66  ? 873  LEU A CB  1 
ATOM   6701  C  CG  . LEU A 1 873 ? 173.795 144.601 142.576 1.00 91.66  ? 873  LEU A CG  1 
ATOM   6702  C  CD1 . LEU A 1 873 ? 174.508 145.768 141.927 1.00 91.66  ? 873  LEU A CD1 1 
ATOM   6703  C  CD2 . LEU A 1 873 ? 172.524 145.074 143.263 1.00 91.66  ? 873  LEU A CD2 1 
ATOM   6704  N  N   . VAL A 1 874 ? 171.580 141.413 142.903 1.00 89.64  ? 874  VAL A N   1 
ATOM   6705  C  CA  . VAL A 1 874 ? 170.712 141.023 144.011 1.00 89.64  ? 874  VAL A CA  1 
ATOM   6706  C  C   . VAL A 1 874 ? 171.191 139.713 144.625 1.00 89.64  ? 874  VAL A C   1 
ATOM   6707  O  O   . VAL A 1 874 ? 171.232 139.563 145.853 1.00 89.64  ? 874  VAL A O   1 
ATOM   6708  C  CB  . VAL A 1 874 ? 169.251 140.929 143.533 1.00 89.64  ? 874  VAL A CB  1 
ATOM   6709  C  CG1 . VAL A 1 874 ? 168.404 140.171 144.543 1.00 89.64  ? 874  VAL A CG1 1 
ATOM   6710  C  CG2 . VAL A 1 874 ? 168.686 142.320 143.291 1.00 89.64  ? 874  VAL A CG2 1 
ATOM   6711  N  N   . ALA A 1 875 ? 171.562 138.747 143.780 1.00 84.75  ? 875  ALA A N   1 
ATOM   6712  C  CA  . ALA A 1 875 ? 172.073 137.478 144.285 1.00 84.75  ? 875  ALA A CA  1 
ATOM   6713  C  C   . ALA A 1 875 ? 173.369 137.673 145.060 1.00 84.75  ? 875  ALA A C   1 
ATOM   6714  O  O   . ALA A 1 875 ? 173.575 137.046 146.105 1.00 84.75  ? 875  ALA A O   1 
ATOM   6715  C  CB  . ALA A 1 875 ? 172.278 136.498 143.131 1.00 84.75  ? 875  ALA A CB  1 
ATOM   6716  N  N   . ILE A 1 876 ? 174.256 138.538 144.562 1.00 84.35  ? 876  ILE A N   1 
ATOM   6717  C  CA  . ILE A 1 876 ? 175.517 138.796 145.253 1.00 84.35  ? 876  ILE A CA  1 
ATOM   6718  C  C   . ILE A 1 876 ? 175.254 139.405 146.625 1.00 84.35  ? 876  ILE A C   1 
ATOM   6719  O  O   . ILE A 1 876 ? 175.857 139.006 147.628 1.00 84.35  ? 876  ILE A O   1 
ATOM   6720  C  CB  . ILE A 1 876 ? 176.424 139.697 144.397 1.00 84.35  ? 876  ILE A CB  1 
ATOM   6721  C  CG1 . ILE A 1 876 ? 176.986 138.915 143.207 1.00 84.35  ? 876  ILE A CG1 1 
ATOM   6722  C  CG2 . ILE A 1 876 ? 177.552 140.277 145.235 1.00 84.35  ? 876  ILE A CG2 1 
ATOM   6723  C  CD1 . ILE A 1 876 ? 177.983 137.846 143.594 1.00 84.35  ? 876  ILE A CD1 1 
ATOM   6724  N  N   . LEU A 1 877 ? 174.346 140.383 146.688 1.00 80.41  ? 877  LEU A N   1 
ATOM   6725  C  CA  . LEU A 1 877 ? 174.027 141.016 147.965 1.00 80.41  ? 877  LEU A CA  1 
ATOM   6726  C  C   . LEU A 1 877 ? 173.417 140.018 148.943 1.00 80.41  ? 877  LEU A C   1 
ATOM   6727  O  O   . LEU A 1 877 ? 173.782 139.993 150.127 1.00 80.41  ? 877  LEU A O   1 
ATOM   6728  C  CB  . LEU A 1 877 ? 173.081 142.196 147.742 1.00 80.41  ? 877  LEU A CB  1 
ATOM   6729  C  CG  . LEU A 1 877 ? 173.657 143.390 146.980 1.00 80.41  ? 877  LEU A CG  1 
ATOM   6730  C  CD1 . LEU A 1 877 ? 172.688 144.561 146.998 1.00 80.41  ? 877  LEU A CD1 1 
ATOM   6731  C  CD2 . LEU A 1 877 ? 175.000 143.796 147.561 1.00 80.41  ? 877  LEU A CD2 1 
ATOM   6732  N  N   . ALA A 1 878 ? 172.483 139.189 148.467 1.00 83.71  ? 878  ALA A N   1 
ATOM   6733  C  CA  . ALA A 1 878 ? 171.861 138.200 149.340 1.00 83.71  ? 878  ALA A CA  1 
ATOM   6734  C  C   . ALA A 1 878 ? 172.884 137.194 149.852 1.00 83.71  ? 878  ALA A C   1 
ATOM   6735  O  O   . ALA A 1 878 ? 172.878 136.839 151.037 1.00 83.71  ? 878  ALA A O   1 
ATOM   6736  C  CB  . ALA A 1 878 ? 170.727 137.488 148.603 1.00 83.71  ? 878  ALA A CB  1 
ATOM   6737  N  N   . GLY A 1 879 ? 173.773 136.726 148.973 1.00 81.89  ? 879  GLY A N   1 
ATOM   6738  C  CA  . GLY A 1 879 ? 174.809 135.805 149.405 1.00 81.89  ? 879  GLY A CA  1 
ATOM   6739  C  C   . GLY A 1 879 ? 175.753 136.426 150.414 1.00 81.89  ? 879  GLY A C   1 
ATOM   6740  O  O   . GLY A 1 879 ? 176.149 135.780 151.385 1.00 81.89  ? 879  GLY A O   1 
ATOM   6741  N  N   . TYR A 1 880 ? 176.125 137.690 150.199 1.00 77.43  ? 880  TYR A N   1 
ATOM   6742  C  CA  . TYR A 1 880 ? 176.996 138.383 151.141 1.00 77.43  ? 880  TYR A CA  1 
ATOM   6743  C  C   . TYR A 1 880 ? 176.342 138.488 152.512 1.00 77.43  ? 880  TYR A C   1 
ATOM   6744  O  O   . TYR A 1 880 ? 176.966 138.188 153.541 1.00 77.43  ? 880  TYR A O   1 
ATOM   6745  C  CB  . TYR A 1 880 ? 177.342 139.767 150.587 1.00 77.43  ? 880  TYR A CB  1 
ATOM   6746  C  CG  . TYR A 1 880 ? 178.283 140.580 151.441 1.00 77.43  ? 880  TYR A CG  1 
ATOM   6747  C  CD1 . TYR A 1 880 ? 179.363 139.988 152.081 1.00 77.43  ? 880  TYR A CD1 1 
ATOM   6748  C  CD2 . TYR A 1 880 ? 178.101 141.947 151.593 1.00 77.43  ? 880  TYR A CD2 1 
ATOM   6749  C  CE1 . TYR A 1 880 ? 180.227 140.734 152.856 1.00 77.43  ? 880  TYR A CE1 1 
ATOM   6750  C  CE2 . TYR A 1 880 ? 178.960 142.701 152.364 1.00 77.43  ? 880  TYR A CE2 1 
ATOM   6751  C  CZ  . TYR A 1 880 ? 180.021 142.089 152.994 1.00 77.43  ? 880  TYR A CZ  1 
ATOM   6752  O  OH  . TYR A 1 880 ? 180.878 142.837 153.766 1.00 77.43  ? 880  TYR A OH  1 
ATOM   6753  N  N   . MET A 1 881 ? 175.069 138.892 152.542 1.00 78.90  ? 881  MET A N   1 
ATOM   6754  C  CA  . MET A 1 881 ? 174.364 139.016 153.814 1.00 78.90  ? 881  MET A CA  1 
ATOM   6755  C  C   . MET A 1 881 ? 174.242 137.667 154.514 1.00 78.90  ? 881  MET A C   1 
ATOM   6756  O  O   . MET A 1 881 ? 174.489 137.561 155.722 1.00 78.90  ? 881  MET A O   1 
ATOM   6757  C  CB  . MET A 1 881 ? 172.984 139.633 153.587 1.00 78.90  ? 881  MET A CB  1 
ATOM   6758  C  CG  . MET A 1 881 ? 173.025 141.077 153.113 1.00 78.90  ? 881  MET A CG  1 
ATOM   6759  S  SD  . MET A 1 881 ? 171.401 141.859 153.100 1.00 78.90  ? 881  MET A SD  1 
ATOM   6760  C  CE  . MET A 1 881 ? 171.482 142.844 154.593 1.00 78.90  ? 881  MET A CE  1 
ATOM   6761  N  N   . THR A 1 882 ? 173.876 136.619 153.771 1.00 79.89  ? 882  THR A N   1 
ATOM   6762  C  CA  . THR A 1 882 ? 173.728 135.303 154.384 1.00 79.89  ? 882  THR A CA  1 
ATOM   6763  C  C   . THR A 1 882 ? 175.059 134.781 154.911 1.00 79.89  ? 882  THR A C   1 
ATOM   6764  O  O   . THR A 1 882 ? 175.121 134.227 156.017 1.00 79.89  ? 882  THR A O   1 
ATOM   6765  C  CB  . THR A 1 882 ? 173.128 134.318 153.382 1.00 79.89  ? 882  THR A CB  1 
ATOM   6766  O  OG1 . THR A 1 882 ? 173.832 134.411 152.138 1.00 79.89  ? 882  THR A OG1 1 
ATOM   6767  C  CG2 . THR A 1 882 ? 171.656 134.626 153.152 1.00 79.89  ? 882  THR A CG2 1 
ATOM   6768  N  N   . LEU A 1 883 ? 176.134 134.947 154.138 1.00 77.91  ? 883  LEU A N   1 
ATOM   6769  C  CA  . LEU A 1 883 ? 177.434 134.454 154.575 1.00 77.91  ? 883  LEU A CA  1 
ATOM   6770  C  C   . LEU A 1 883 ? 177.910 135.189 155.818 1.00 77.91  ? 883  LEU A C   1 
ATOM   6771  O  O   . LEU A 1 883 ? 178.413 134.563 156.757 1.00 77.91  ? 883  LEU A O   1 
ATOM   6772  C  CB  . LEU A 1 883 ? 178.459 134.582 153.449 1.00 77.91  ? 883  LEU A CB  1 
ATOM   6773  C  CG  . LEU A 1 883 ? 179.869 134.112 153.816 1.00 77.91  ? 883  LEU A CG  1 
ATOM   6774  C  CD1 . LEU A 1 883 ? 179.834 132.687 154.347 1.00 77.91  ? 883  LEU A CD1 1 
ATOM   6775  C  CD2 . LEU A 1 883 ? 180.810 134.210 152.628 1.00 77.91  ? 883  LEU A CD2 1 
ATOM   6776  N  N   . THR A 1 884 ? 177.752 136.516 155.856 1.00 80.06  ? 884  THR A N   1 
ATOM   6777  C  CA  . THR A 1 884 ? 178.191 137.245 157.042 1.00 80.06  ? 884  THR A CA  1 
ATOM   6778  C  C   . THR A 1 884 ? 177.331 136.893 158.254 1.00 80.06  ? 884  THR A C   1 
ATOM   6779  O  O   . THR A 1 884 ? 177.843 136.809 159.379 1.00 80.06  ? 884  THR A O   1 
ATOM   6780  C  CB  . THR A 1 884 ? 178.200 138.755 156.774 1.00 80.06  ? 884  THR A CB  1 
ATOM   6781  O  OG1 . THR A 1 884 ? 178.942 139.420 157.805 1.00 80.06  ? 884  THR A OG1 1 
ATOM   6782  C  CG2 . THR A 1 884 ? 176.797 139.327 156.723 1.00 80.06  ? 884  THR A CG2 1 
ATOM   6783  N  N   . GLN A 1 885 ? 176.033 136.646 158.044 1.00 79.94  ? 885  GLN A N   1 
ATOM   6784  C  CA  . GLN A 1 885 ? 175.176 136.237 159.152 1.00 79.94  ? 885  GLN A CA  1 
ATOM   6785  C  C   . GLN A 1 885 ? 175.602 134.884 159.707 1.00 79.94  ? 885  GLN A C   1 
ATOM   6786  O  O   . GLN A 1 885 ? 175.644 134.693 160.928 1.00 79.94  ? 885  GLN A O   1 
ATOM   6787  C  CB  . GLN A 1 885 ? 173.717 136.201 158.698 1.00 79.94  ? 885  GLN A CB  1 
ATOM   6788  C  CG  . GLN A 1 885 ? 172.770 135.508 159.666 1.00 79.94  ? 885  GLN A CG  1 
ATOM   6789  C  CD  . GLN A 1 885 ? 172.868 136.058 161.075 1.00 79.94  ? 885  GLN A CD  1 
ATOM   6790  O  OE1 . GLN A 1 885 ? 172.554 137.221 161.323 1.00 79.94  ? 885  GLN A OE1 1 
ATOM   6791  N  NE2 . GLN A 1 885 ? 173.306 135.220 162.008 1.00 79.94  ? 885  GLN A NE2 1 
ATOM   6792  N  N   . LEU A 1 886 ? 175.927 133.933 158.829 1.00 80.16  ? 886  LEU A N   1 
ATOM   6793  C  CA  . LEU A 1 886 ? 176.353 132.619 159.302 1.00 80.16  ? 886  LEU A CA  1 
ATOM   6794  C  C   . LEU A 1 886 ? 177.759 132.654 159.891 1.00 80.16  ? 886  LEU A C   1 
ATOM   6795  O  O   . LEU A 1 886 ? 178.100 131.808 160.725 1.00 80.16  ? 886  LEU A O   1 
ATOM   6796  C  CB  . LEU A 1 886 ? 176.275 131.594 158.170 1.00 80.16  ? 886  LEU A CB  1 
ATOM   6797  C  CG  . LEU A 1 886 ? 174.946 130.860 157.954 1.00 80.16  ? 886  LEU A CG  1 
ATOM   6798  C  CD1 . LEU A 1 886 ? 174.618 129.992 159.159 1.00 80.16  ? 886  LEU A CD1 1 
ATOM   6799  C  CD2 . LEU A 1 886 ? 173.798 131.815 157.656 1.00 80.16  ? 886  LEU A CD2 1 
ATOM   6800  N  N   . VAL A 1 887 ? 178.584 133.616 159.477 1.00 79.10  ? 887  VAL A N   1 
ATOM   6801  C  CA  . VAL A 1 887 ? 179.957 133.697 159.964 1.00 79.10  ? 887  VAL A CA  1 
ATOM   6802  C  C   . VAL A 1 887 ? 180.071 134.453 161.287 1.00 79.10  ? 887  VAL A C   1 
ATOM   6803  O  O   . VAL A 1 887 ? 180.997 134.180 162.067 1.00 79.10  ? 887  VAL A O   1 
ATOM   6804  C  CB  . VAL A 1 887 ? 180.841 134.324 158.867 1.00 79.10  ? 887  VAL A CB  1 
ATOM   6805  C  CG1 . VAL A 1 887 ? 182.147 134.855 159.424 1.00 79.10  ? 887  VAL A CG1 1 
ATOM   6806  C  CG2 . VAL A 1 887 ? 181.124 133.301 157.778 1.00 79.10  ? 887  VAL A CG2 1 
ATOM   6807  N  N   . LYS A 1 888 ? 179.128 135.353 161.587 1.00 78.40  ? 888  LYS A N   1 
ATOM   6808  C  CA  . LYS A 1 888 ? 179.192 136.128 162.827 1.00 78.40  ? 888  LYS A CA  1 
ATOM   6809  C  C   . LYS A 1 888 ? 179.282 135.234 164.060 1.00 78.40  ? 888  LYS A C   1 
ATOM   6810  O  O   . LYS A 1 888 ? 179.836 135.638 165.092 1.00 78.40  ? 888  LYS A O   1 
ATOM   6811  C  CB  . LYS A 1 888 ? 177.971 137.040 162.931 1.00 78.40  ? 888  LYS A CB  1 
ATOM   6812  C  CG  . LYS A 1 888 ? 178.160 138.414 162.321 1.00 78.40  ? 888  LYS A CG  1 
ATOM   6813  C  CD  . LYS A 1 888 ? 176.822 139.063 162.014 1.00 78.40  ? 888  LYS A CD  1 
ATOM   6814  C  CE  . LYS A 1 888 ? 175.824 138.840 163.139 1.00 78.40  ? 888  LYS A CE  1 
ATOM   6815  N  NZ  . LYS A 1 888 ? 174.529 139.523 162.876 1.00 78.40  ? 888  LYS A NZ  1 
ATOM   6816  N  N   . GLY A 1 889 ? 178.727 134.023 163.980 1.00 83.85  ? 889  GLY A N   1 
ATOM   6817  C  CA  . GLY A 1 889 ? 178.764 133.125 165.123 1.00 83.85  ? 889  GLY A CA  1 
ATOM   6818  C  C   . GLY A 1 889 ? 180.173 132.744 165.535 1.00 83.85  ? 889  GLY A C   1 
ATOM   6819  O  O   . GLY A 1 889 ? 180.477 132.658 166.727 1.00 83.85  ? 889  GLY A O   1 
ATOM   6820  N  N   . PHE A 1 890 ? 181.050 132.501 164.558 1.00 85.74  ? 890  PHE A N   1 
ATOM   6821  C  CA  . PHE A 1 890 ? 182.429 132.142 164.880 1.00 85.74  ? 890  PHE A CA  1 
ATOM   6822  C  C   . PHE A 1 890 ? 183.147 133.289 165.579 1.00 85.74  ? 890  PHE A C   1 
ATOM   6823  O  O   . PHE A 1 890 ? 183.902 133.070 166.535 1.00 85.74  ? 890  PHE A O   1 
ATOM   6824  C  CB  . PHE A 1 890 ? 183.178 131.730 163.613 1.00 85.74  ? 890  PHE A CB  1 
ATOM   6825  C  CG  . PHE A 1 890 ? 182.829 130.354 163.118 1.00 85.74  ? 890  PHE A CG  1 
ATOM   6826  C  CD1 . PHE A 1 890 ? 181.530 130.039 162.752 1.00 85.74  ? 890  PHE A CD1 1 
ATOM   6827  C  CD2 . PHE A 1 890 ? 183.802 129.374 163.022 1.00 85.74  ? 890  PHE A CD2 1 
ATOM   6828  C  CE1 . PHE A 1 890 ? 181.210 128.774 162.299 1.00 85.74  ? 890  PHE A CE1 1 
ATOM   6829  C  CE2 . PHE A 1 890 ? 183.488 128.107 162.569 1.00 85.74  ? 890  PHE A CE2 1 
ATOM   6830  C  CZ  . PHE A 1 890 ? 182.191 127.806 162.207 1.00 85.74  ? 890  PHE A CZ  1 
ATOM   6831  N  N   . TYR A 1 891 ? 182.928 134.521 165.112 1.00 81.16  ? 891  TYR A N   1 
ATOM   6832  C  CA  . TYR A 1 891 ? 183.503 135.680 165.785 1.00 81.16  ? 891  TYR A CA  1 
ATOM   6833  C  C   . TYR A 1 891 ? 182.959 135.812 167.200 1.00 81.16  ? 891  TYR A C   1 
ATOM   6834  O  O   . TYR A 1 891 ? 183.694 136.173 168.126 1.00 81.16  ? 891  TYR A O   1 
ATOM   6835  C  CB  . TYR A 1 891 ? 183.220 136.948 164.981 1.00 81.16  ? 891  TYR A CB  1 
ATOM   6836  C  CG  . TYR A 1 891 ? 183.843 138.199 165.559 1.00 81.16  ? 891  TYR A CG  1 
ATOM   6837  C  CD1 . TYR A 1 891 ? 185.204 138.442 165.435 1.00 81.16  ? 891  TYR A CD1 1 
ATOM   6838  C  CD2 . TYR A 1 891 ? 183.068 139.139 166.224 1.00 81.16  ? 891  TYR A CD2 1 
ATOM   6839  C  CE1 . TYR A 1 891 ? 185.777 139.585 165.959 1.00 81.16  ? 891  TYR A CE1 1 
ATOM   6840  C  CE2 . TYR A 1 891 ? 183.631 140.285 166.751 1.00 81.16  ? 891  TYR A CE2 1 
ATOM   6841  C  CZ  . TYR A 1 891 ? 184.986 140.502 166.616 1.00 81.16  ? 891  TYR A CZ  1 
ATOM   6842  O  OH  . TYR A 1 891 ? 185.551 141.642 167.140 1.00 81.16  ? 891  TYR A OH  1 
ATOM   6843  N  N   . SER A 1 892 ? 181.666 135.532 167.382 1.00 86.51  ? 892  SER A N   1 
ATOM   6844  C  CA  . SER A 1 892 ? 181.081 135.591 168.718 1.00 86.51  ? 892  SER A CA  1 
ATOM   6845  C  C   . SER A 1 892 ? 181.714 134.561 169.647 1.00 86.51  ? 892  SER A C   1 
ATOM   6846  O  O   . SER A 1 892 ? 182.018 134.864 170.807 1.00 86.51  ? 892  SER A O   1 
ATOM   6847  C  CB  . SER A 1 892 ? 179.570 135.380 168.635 1.00 86.51  ? 892  SER A CB  1 
ATOM   6848  O  OG  . SER A 1 892 ? 178.952 136.422 167.900 1.00 86.51  ? 892  SER A OG  1 
ATOM   6849  N  N   . ARG A 1 893 ? 181.913 133.335 169.159 1.00 87.00  ? 893  ARG A N   1 
ATOM   6850  C  CA  . ARG A 1 893 ? 182.495 132.291 169.999 1.00 87.00  ? 893  ARG A CA  1 
ATOM   6851  C  C   . ARG A 1 893 ? 183.952 132.588 170.335 1.00 87.00  ? 893  ARG A C   1 
ATOM   6852  O  O   . ARG A 1 893 ? 184.350 132.542 171.505 1.00 87.00  ? 893  ARG A O   1 
ATOM   6853  C  CB  . ARG A 1 893 ? 182.378 130.924 169.319 1.00 87.00  ? 893  ARG A CB  1 
ATOM   6854  C  CG  . ARG A 1 893 ? 180.980 130.548 168.865 1.00 87.00  ? 893  ARG A CG  1 
ATOM   6855  C  CD  . ARG A 1 893 ? 180.097 130.153 170.038 1.00 87.00  ? 893  ARG A CD  1 
ATOM   6856  N  NE  . ARG A 1 893 ? 178.709 129.948 169.639 1.00 87.00  ? 893  ARG A NE  1 
ATOM   6857  C  CZ  . ARG A 1 893 ? 178.280 128.945 168.883 1.00 87.00  ? 893  ARG A CZ  1 
ATOM   6858  N  NH1 . ARG A 1 893 ? 179.104 128.013 168.433 1.00 87.00  ? 893  ARG A NH1 1 
ATOM   6859  N  NH2 . ARG A 1 893 ? 176.988 128.873 168.575 1.00 87.00  ? 893  ARG A NH2 1 
ATOM   6860  N  N   . ARG A 1 894 ? 184.767 132.895 169.321 1.00 90.24  ? 894  ARG A N   1 
ATOM   6861  C  CA  . ARG A 1 894 ? 186.208 132.979 169.547 1.00 90.24  ? 894  ARG A CA  1 
ATOM   6862  C  C   . ARG A 1 894 ? 186.588 134.224 170.340 1.00 90.24  ? 894  ARG A C   1 
ATOM   6863  O  O   . ARG A 1 894 ? 187.379 134.142 171.288 1.00 90.24  ? 894  ARG A O   1 
ATOM   6864  C  CB  . ARG A 1 894 ? 186.953 132.948 168.213 1.00 90.24  ? 894  ARG A CB  1 
ATOM   6865  C  CG  . ARG A 1 894 ? 188.451 133.176 168.347 1.00 90.24  ? 894  ARG A CG  1 
ATOM   6866  C  CD  . ARG A 1 894 ? 189.102 132.120 169.226 1.00 90.24  ? 894  ARG A CD  1 
ATOM   6867  N  NE  . ARG A 1 894 ? 190.498 132.432 169.512 1.00 90.24  ? 894  ARG A NE  1 
ATOM   6868  C  CZ  . ARG A 1 894 ? 191.517 132.092 168.735 1.00 90.24  ? 894  ARG A CZ  1 
ATOM   6869  N  NH1 . ARG A 1 894 ? 191.336 131.421 167.610 1.00 90.24  ? 894  ARG A NH1 1 
ATOM   6870  N  NH2 . ARG A 1 894 ? 192.751 132.434 169.098 1.00 90.24  ? 894  ARG A NH2 1 
ATOM   6871  N  N   . TYR A 1 895 ? 186.041 135.381 169.978 1.00 88.37  ? 895  TYR A N   1 
ATOM   6872  C  CA  . TYR A 1 895 ? 186.420 136.639 170.611 1.00 88.37  ? 895  TYR A CA  1 
ATOM   6873  C  C   . TYR A 1 895 ? 185.285 137.268 171.400 1.00 88.37  ? 895  TYR A C   1 
ATOM   6874  O  O   . TYR A 1 895 ? 185.517 137.798 172.494 1.00 88.37  ? 895  TYR A O   1 
ATOM   6875  C  CB  . TYR A 1 895 ? 186.932 137.629 169.553 1.00 88.37  ? 895  TYR A CB  1 
ATOM   6876  C  CG  . TYR A 1 895 ? 187.933 137.039 168.584 1.00 88.37  ? 895  TYR A CG  1 
ATOM   6877  C  CD1 . TYR A 1 895 ? 189.258 136.847 168.955 1.00 88.37  ? 895  TYR A CD1 1 
ATOM   6878  C  CD2 . TYR A 1 895 ? 187.555 136.681 167.297 1.00 88.37  ? 895  TYR A CD2 1 
ATOM   6879  C  CE1 . TYR A 1 895 ? 190.178 136.313 168.072 1.00 88.37  ? 895  TYR A CE1 1 
ATOM   6880  C  CE2 . TYR A 1 895 ? 188.467 136.145 166.406 1.00 88.37  ? 895  TYR A CE2 1 
ATOM   6881  C  CZ  . TYR A 1 895 ? 189.777 135.963 166.799 1.00 88.37  ? 895  TYR A CZ  1 
ATOM   6882  O  OH  . TYR A 1 895 ? 190.690 135.430 165.919 1.00 88.37  ? 895  TYR A OH  1 
ATOM   6883  N  N   . GLY A 1 896 ? 184.065 137.231 170.881 1.00 89.16  ? 896  GLY A N   1 
ATOM   6884  C  CA  . GLY A 1 896 ? 182.940 137.849 171.545 1.00 89.16  ? 896  GLY A CA  1 
ATOM   6885  C  C   . GLY A 1 896 ? 182.629 139.227 170.982 1.00 89.16  ? 896  GLY A C   1 
ATOM   6886  O  O   . GLY A 1 896 ? 183.485 139.917 170.422 1.00 89.16  ? 896  GLY A O   1 
ATOM   6887  N  N   . TRP A 1 897 ? 181.369 139.632 171.138 1.00 84.25  ? 897  TRP A N   1 
ATOM   6888  C  CA  . TRP A 1 897 ? 180.932 140.921 170.614 1.00 84.25  ? 897  TRP A CA  1 
ATOM   6889  C  C   . TRP A 1 897 ? 181.362 142.063 171.529 1.00 84.25  ? 897  TRP A C   1 
ATOM   6890  O  O   . TRP A 1 897 ? 182.073 142.980 171.105 1.00 84.25  ? 897  TRP A O   1 
ATOM   6891  C  CB  . TRP A 1 897 ? 179.414 140.923 170.427 1.00 84.25  ? 897  TRP A CB  1 
ATOM   6892  C  CG  . TRP A 1 897 ? 178.894 142.181 169.807 1.00 84.25  ? 897  TRP A CG  1 
ATOM   6893  C  CD1 . TRP A 1 897 ? 178.481 143.307 170.457 1.00 84.25  ? 897  TRP A CD1 1 
ATOM   6894  C  CD2 . TRP A 1 897 ? 178.729 142.440 168.409 1.00 84.25  ? 897  TRP A CD2 1 
ATOM   6895  N  NE1 . TRP A 1 897 ? 178.071 144.253 169.549 1.00 84.25  ? 897  TRP A NE1 1 
ATOM   6896  C  CE2 . TRP A 1 897 ? 178.213 143.745 168.285 1.00 84.25  ? 897  TRP A CE2 1 
ATOM   6897  C  CE3 . TRP A 1 897 ? 178.969 141.696 167.249 1.00 84.25  ? 897  TRP A CE3 1 
ATOM   6898  C  CZ2 . TRP A 1 897 ? 177.931 144.321 167.048 1.00 84.25  ? 897  TRP A CZ2 1 
ATOM   6899  C  CZ3 . TRP A 1 897 ? 178.689 142.269 166.024 1.00 84.25  ? 897  TRP A CZ3 1 
ATOM   6900  C  CH2 . TRP A 1 897 ? 178.176 143.569 165.932 1.00 84.25  ? 897  TRP A CH2 1 
ATOM   6901  N  N   . GLN A 1 898 ? 180.934 142.023 172.786 1.00 91.34  ? 898  GLN A N   1 
ATOM   6902  C  CA  . GLN A 1 898 ? 181.271 143.070 173.744 1.00 91.34  ? 898  GLN A CA  1 
ATOM   6903  C  C   . GLN A 1 898 ? 182.460 142.665 174.609 1.00 91.34  ? 898  GLN A C   1 
ATOM   6904  O  O   . GLN A 1 898 ? 183.156 143.512 175.170 1.00 91.34  ? 898  GLN A O   1 
ATOM   6905  C  CB  . GLN A 1 898 ? 180.063 143.397 174.625 1.00 91.34  ? 898  GLN A CB  1 
ATOM   6906  N  N   . MET B 1 1   ? 109.876 168.153 162.251 1.00 112.32 ? 1    MET B N   1 
ATOM   6907  C  CA  . MET B 1 1   ? 111.084 167.453 162.672 1.00 112.32 ? 1    MET B CA  1 
ATOM   6908  C  C   . MET B 1 1   ? 110.832 165.954 162.808 1.00 112.32 ? 1    MET B C   1 
ATOM   6909  O  O   . MET B 1 1   ? 111.083 165.190 161.874 1.00 112.32 ? 1    MET B O   1 
ATOM   6910  C  CB  . MET B 1 1   ? 111.601 168.023 163.994 1.00 112.32 ? 1    MET B CB  1 
ATOM   6911  N  N   . PHE B 1 2   ? 110.327 165.550 163.976 1.00 106.25 ? 2    PHE B N   1 
ATOM   6912  C  CA  . PHE B 1 2   ? 110.047 164.150 164.279 1.00 106.25 ? 2    PHE B CA  1 
ATOM   6913  C  C   . PHE B 1 2   ? 111.273 163.279 164.035 1.00 106.25 ? 2    PHE B C   1 
ATOM   6914  O  O   . PHE B 1 2   ? 112.157 163.189 164.894 1.00 106.25 ? 2    PHE B O   1 
ATOM   6915  C  CB  . PHE B 1 2   ? 108.861 163.647 163.451 1.00 106.25 ? 2    PHE B CB  1 
ATOM   6916  N  N   . LYS B 1 3   ? 111.325 162.637 162.867 1.00 103.03 ? 3    LYS B N   1 
ATOM   6917  C  CA  . LYS B 1 3   ? 112.465 161.813 162.461 1.00 103.03 ? 3    LYS B CA  1 
ATOM   6918  C  C   . LYS B 1 3   ? 112.731 160.691 163.461 1.00 103.03 ? 3    LYS B C   1 
ATOM   6919  O  O   . LYS B 1 3   ? 113.857 160.495 163.924 1.00 103.03 ? 3    LYS B O   1 
ATOM   6920  C  CB  . LYS B 1 3   ? 113.716 162.670 162.255 1.00 103.03 ? 3    LYS B CB  1 
ATOM   6921  N  N   . GLU B 1 4   ? 111.677 159.948 163.806 1.00 98.45  ? 4    GLU B N   1 
ATOM   6922  C  CA  . GLU B 1 4   ? 111.850 158.766 164.641 1.00 98.45  ? 4    GLU B CA  1 
ATOM   6923  C  C   . GLU B 1 4   ? 112.663 157.689 163.935 1.00 98.45  ? 4    GLU B C   1 
ATOM   6924  O  O   . GLU B 1 4   ? 113.451 156.991 164.586 1.00 98.45  ? 4    GLU B O   1 
ATOM   6925  C  CB  . GLU B 1 4   ? 110.488 158.208 165.056 1.00 98.45  ? 4    GLU B CB  1 
ATOM   6926  N  N   . ILE B 1 5   ? 112.506 157.555 162.613 1.00 94.65  ? 5    ILE B N   1 
ATOM   6927  C  CA  . ILE B 1 5   ? 113.274 156.579 161.841 1.00 94.65  ? 5    ILE B CA  1 
ATOM   6928  C  C   . ILE B 1 5   ? 114.770 156.826 161.902 1.00 94.65  ? 5    ILE B C   1 
ATOM   6929  O  O   . ILE B 1 5   ? 115.546 155.978 161.441 1.00 94.65  ? 5    ILE B O   1 
ATOM   6930  C  CB  . ILE B 1 5   ? 112.827 156.565 160.366 1.00 94.65  ? 5    ILE B CB  1 
ATOM   6931  N  N   . PHE B 1 6   ? 115.203 157.964 162.454 1.00 87.89  ? 6    PHE B N   1 
ATOM   6932  C  CA  . PHE B 1 6   ? 116.624 158.176 162.698 1.00 87.89  ? 6    PHE B CA  1 
ATOM   6933  C  C   . PHE B 1 6   ? 117.189 157.112 163.627 1.00 87.89  ? 6    PHE B C   1 
ATOM   6934  O  O   . PHE B 1 6   ? 118.387 156.813 163.571 1.00 87.89  ? 6    PHE B O   1 
ATOM   6935  C  CB  . PHE B 1 6   ? 116.860 159.569 163.284 1.00 87.89  ? 6    PHE B CB  1 
ATOM   6936  N  N   . THR B 1 7   ? 116.345 156.528 164.483 1.00 89.37  ? 7    THR B N   1 
ATOM   6937  C  CA  . THR B 1 7   ? 116.791 155.407 165.305 1.00 89.37  ? 7    THR B CA  1 
ATOM   6938  C  C   . THR B 1 7   ? 117.308 154.268 164.436 1.00 89.37  ? 7    THR B C   1 
ATOM   6939  O  O   . THR B 1 7   ? 118.281 153.594 164.793 1.00 89.37  ? 7    THR B O   1 
ATOM   6940  C  CB  . THR B 1 7   ? 115.650 154.923 166.200 1.00 89.37  ? 7    THR B CB  1 
ATOM   6941  O  OG1 . THR B 1 7   ? 114.513 154.595 165.391 1.00 89.37  ? 7    THR B OG1 1 
ATOM   6942  C  CG2 . THR B 1 7   ? 115.260 156.005 167.196 1.00 89.37  ? 7    THR B CG2 1 
ATOM   6943  N  N   . ARG B 1 8   ? 116.663 154.036 163.291 1.00 87.35  ? 8    ARG B N   1 
ATOM   6944  C  CA  . ARG B 1 8   ? 117.189 153.089 162.315 1.00 87.35  ? 8    ARG B CA  1 
ATOM   6945  C  C   . ARG B 1 8   ? 118.506 153.583 161.729 1.00 87.35  ? 8    ARG B C   1 
ATOM   6946  O  O   . ARG B 1 8   ? 119.458 152.811 161.564 1.00 87.35  ? 8    ARG B O   1 
ATOM   6947  C  CB  . ARG B 1 8   ? 116.156 152.861 161.211 1.00 87.35  ? 8    ARG B CB  1 
ATOM   6948  C  CG  . ARG B 1 8   ? 116.724 152.349 159.898 1.00 87.35  ? 8    ARG B CG  1 
ATOM   6949  C  CD  . ARG B 1 8   ? 116.903 150.841 159.913 1.00 87.35  ? 8    ARG B CD  1 
ATOM   6950  N  NE  . ARG B 1 8   ? 117.450 150.349 158.655 1.00 87.35  ? 8    ARG B NE  1 
ATOM   6951  C  CZ  . ARG B 1 8   ? 118.536 149.596 158.552 1.00 87.35  ? 8    ARG B CZ  1 
ATOM   6952  N  NH1 . ARG B 1 8   ? 119.219 149.219 159.621 1.00 87.35  ? 8    ARG B NH1 1 
ATOM   6953  N  NH2 . ARG B 1 8   ? 118.946 149.210 157.348 1.00 87.35  ? 8    ARG B NH2 1 
ATOM   6954  N  N   . LEU B 1 9   ? 118.581 154.877 161.416 1.00 83.39  ? 9    LEU B N   1 
ATOM   6955  C  CA  . LEU B 1 9   ? 119.753 155.458 160.771 1.00 83.39  ? 9    LEU B CA  1 
ATOM   6956  C  C   . LEU B 1 9   ? 120.984 155.417 161.668 1.00 83.39  ? 9    LEU B C   1 
ATOM   6957  O  O   . LEU B 1 9   ? 122.048 154.952 161.246 1.00 83.39  ? 9    LEU B O   1 
ATOM   6958  C  CB  . LEU B 1 9   ? 119.462 156.900 160.348 1.00 83.39  ? 9    LEU B CB  1 
ATOM   6959  C  CG  . LEU B 1 9   ? 118.426 157.086 159.239 1.00 83.39  ? 9    LEU B CG  1 
ATOM   6960  C  CD1 . LEU B 1 9   ? 117.978 158.536 159.153 1.00 83.39  ? 9    LEU B CD1 1 
ATOM   6961  C  CD2 . LEU B 1 9   ? 119.001 156.624 157.911 1.00 83.39  ? 9    LEU B CD2 1 
ATOM   6962  N  N   . ILE B 1 10  ? 120.856 155.905 162.900 1.00 73.59  ? 10   ILE B N   1 
ATOM   6963  C  CA  . ILE B 1 10  ? 121.989 155.979 163.815 1.00 73.59  ? 10   ILE B CA  1 
ATOM   6964  C  C   . ILE B 1 10  ? 122.390 154.583 164.269 1.00 73.59  ? 10   ILE B C   1 
ATOM   6965  O  O   . ILE B 1 10  ? 121.569 153.834 164.810 1.00 73.59  ? 10   ILE B O   1 
ATOM   6966  C  CB  . ILE B 1 10  ? 121.669 156.868 165.030 1.00 73.59  ? 10   ILE B CB  1 
ATOM   6967  C  CG1 . ILE B 1 10  ? 121.019 158.176 164.583 1.00 73.59  ? 10   ILE B CG1 1 
ATOM   6968  C  CG2 . ILE B 1 10  ? 122.931 157.149 165.824 1.00 73.59  ? 10   ILE B CG2 1 
ATOM   6969  C  CD1 . ILE B 1 10  ? 120.760 159.147 165.712 1.00 73.59  ? 10   ILE B CD1 1 
ATOM   6970  N  N   . ARG B 1 11  ? 123.653 154.226 164.059 1.00 64.17  ? 11   ARG B N   1 
ATOM   6971  C  CA  . ARG B 1 11  ? 124.191 153.010 164.644 1.00 64.17  ? 11   ARG B CA  1 
ATOM   6972  C  C   . ARG B 1 11  ? 124.951 153.338 165.922 1.00 64.17  ? 11   ARG B C   1 
ATOM   6973  O  O   . ARG B 1 11  ? 125.818 154.215 165.948 1.00 64.17  ? 11   ARG B O   1 
ATOM   6974  C  CB  . ARG B 1 11  ? 125.111 152.285 163.661 1.00 64.17  ? 11   ARG B CB  1 
ATOM   6975  C  CG  . ARG B 1 11  ? 125.448 150.865 164.090 1.00 64.17  ? 11   ARG B CG  1 
ATOM   6976  C  CD  . ARG B 1 11  ? 126.346 150.159 163.087 1.00 64.17  ? 11   ARG B CD  1 
ATOM   6977  N  NE  . ARG B 1 11  ? 127.752 150.497 163.269 1.00 64.17  ? 11   ARG B NE  1 
ATOM   6978  C  CZ  . ARG B 1 11  ? 128.550 150.930 162.302 1.00 64.17  ? 11   ARG B CZ  1 
ATOM   6979  N  NH1 . ARG B 1 11  ? 128.116 151.073 161.061 1.00 64.17  ? 11   ARG B NH1 1 
ATOM   6980  N  NH2 . ARG B 1 11  ? 129.816 151.218 162.586 1.00 64.17  ? 11   ARG B NH2 1 
ATOM   6981  N  N   . HIS B 1 12  ? 124.615 152.621 166.988 1.00 63.63  ? 12   HIS B N   1 
ATOM   6982  C  CA  . HIS B 1 12  ? 125.194 152.847 168.304 1.00 63.63  ? 12   HIS B CA  1 
ATOM   6983  C  C   . HIS B 1 12  ? 126.433 151.981 168.473 1.00 63.63  ? 12   HIS B C   1 
ATOM   6984  O  O   . HIS B 1 12  ? 126.465 150.837 168.008 1.00 63.63  ? 12   HIS B O   1 
ATOM   6985  C  CB  . HIS B 1 12  ? 124.179 152.543 169.409 1.00 63.63  ? 12   HIS B CB  1 
ATOM   6986  C  CG  . HIS B 1 12  ? 123.138 153.605 169.581 1.00 63.63  ? 12   HIS B CG  1 
ATOM   6987  N  ND1 . HIS B 1 12  ? 123.455 154.927 169.809 1.00 63.63  ? 12   HIS B ND1 1 
ATOM   6988  C  CD2 . HIS B 1 12  ? 121.786 153.541 169.558 1.00 63.63  ? 12   HIS B CD2 1 
ATOM   6989  C  CE1 . HIS B 1 12  ? 122.343 155.631 169.919 1.00 63.63  ? 12   HIS B CE1 1 
ATOM   6990  N  NE2 . HIS B 1 12  ? 121.316 154.814 169.771 1.00 63.63  ? 12   HIS B NE2 1 
ATOM   6991  N  N   . LEU B 1 13  ? 127.447 152.532 169.135 1.00 51.18  ? 13   LEU B N   1 
ATOM   6992  C  CA  . LEU B 1 13  ? 128.675 151.809 169.427 1.00 51.18  ? 13   LEU B CA  1 
ATOM   6993  C  C   . LEU B 1 13  ? 128.360 150.641 170.353 1.00 51.18  ? 13   LEU B C   1 
ATOM   6994  O  O   . LEU B 1 13  ? 127.360 150.686 171.081 1.00 51.18  ? 13   LEU B O   1 
ATOM   6995  C  CB  . LEU B 1 13  ? 129.711 152.737 170.065 1.00 51.18  ? 13   LEU B CB  1 
ATOM   6996  C  CG  . LEU B 1 13  ? 130.217 153.915 169.233 1.00 51.18  ? 13   LEU B CG  1 
ATOM   6997  C  CD1 . LEU B 1 13  ? 129.408 155.170 169.521 1.00 51.18  ? 13   LEU B CD1 1 
ATOM   6998  C  CD2 . LEU B 1 13  ? 131.692 154.155 169.508 1.00 51.18  ? 13   LEU B CD2 1 
ATOM   6999  N  N   . PRO B 1 14  ? 129.164 149.579 170.342 1.00 50.02  ? 14   PRO B N   1 
ATOM   7000  C  CA  . PRO B 1 14  ? 128.913 148.458 171.256 1.00 50.02  ? 14   PRO B CA  1 
ATOM   7001  C  C   . PRO B 1 14  ? 128.922 148.921 172.706 1.00 50.02  ? 14   PRO B C   1 
ATOM   7002  O  O   . PRO B 1 14  ? 129.699 149.794 173.097 1.00 50.02  ? 14   PRO B O   1 
ATOM   7003  C  CB  . PRO B 1 14  ? 130.063 147.487 170.961 1.00 50.02  ? 14   PRO B CB  1 
ATOM   7004  C  CG  . PRO B 1 14  ? 131.048 148.256 170.136 1.00 50.02  ? 14   PRO B CG  1 
ATOM   7005  C  CD  . PRO B 1 14  ? 130.274 149.303 169.417 1.00 50.02  ? 14   PRO B CD  1 
ATOM   7006  N  N   . SER B 1 15  ? 128.042 148.323 173.506 1.00 49.10  ? 15   SER B N   1 
ATOM   7007  C  CA  . SER B 1 15  ? 127.800 148.752 174.877 1.00 49.10  ? 15   SER B CA  1 
ATOM   7008  C  C   . SER B 1 15  ? 128.928 148.380 175.834 1.00 49.10  ? 15   SER B C   1 
ATOM   7009  O  O   . SER B 1 15  ? 128.759 148.530 177.050 1.00 49.10  ? 15   SER B O   1 
ATOM   7010  C  CB  . SER B 1 15  ? 126.476 148.172 175.379 1.00 49.10  ? 15   SER B CB  1 
ATOM   7011  O  OG  . SER B 1 15  ? 126.249 148.517 176.734 1.00 49.10  ? 15   SER B OG  1 
ATOM   7012  N  N   . ARG B 1 16  ? 130.063 147.893 175.333 1.00 49.11  ? 16   ARG B N   1 
ATOM   7013  C  CA  . ARG B 1 16  ? 131.196 147.549 176.185 1.00 49.11  ? 16   ARG B CA  1 
ATOM   7014  C  C   . ARG B 1 16  ? 132.291 148.611 176.131 1.00 49.11  ? 16   ARG B C   1 
ATOM   7015  O  O   . ARG B 1 16  ? 132.962 148.863 177.136 1.00 49.11  ? 16   ARG B O   1 
ATOM   7016  C  CB  . ARG B 1 16  ? 131.745 146.169 175.797 1.00 49.11  ? 16   ARG B CB  1 
ATOM   7017  C  CG  . ARG B 1 16  ? 132.346 146.090 174.407 1.00 49.11  ? 16   ARG B CG  1 
ATOM   7018  C  CD  . ARG B 1 16  ? 132.742 144.667 174.066 1.00 49.11  ? 16   ARG B CD  1 
ATOM   7019  N  NE  . ARG B 1 16  ? 133.441 144.590 172.790 1.00 49.11  ? 16   ARG B NE  1 
ATOM   7020  C  CZ  . ARG B 1 16  ? 132.840 144.483 171.613 1.00 49.11  ? 16   ARG B CZ  1 
ATOM   7021  N  NH1 . ARG B 1 16  ? 131.521 144.446 171.512 1.00 49.11  ? 16   ARG B NH1 1 
ATOM   7022  N  NH2 . ARG B 1 16  ? 133.580 144.413 170.510 1.00 49.11  ? 16   ARG B NH2 1 
ATOM   7023  N  N   . LEU B 1 17  ? 132.487 149.243 174.971 1.00 45.35  ? 17   LEU B N   1 
ATOM   7024  C  CA  . LEU B 1 17  ? 133.433 150.352 174.890 1.00 45.35  ? 17   LEU B CA  1 
ATOM   7025  C  C   . LEU B 1 17  ? 132.916 151.569 175.644 1.00 45.35  ? 17   LEU B C   1 
ATOM   7026  O  O   . LEU B 1 17  ? 133.664 152.217 176.385 1.00 45.35  ? 17   LEU B O   1 
ATOM   7027  C  CB  . LEU B 1 17  ? 133.712 150.709 173.431 1.00 45.35  ? 17   LEU B CB  1 
ATOM   7028  C  CG  . LEU B 1 17  ? 133.939 149.553 172.462 1.00 45.35  ? 17   LEU B CG  1 
ATOM   7029  C  CD1 . LEU B 1 17  ? 134.015 150.080 171.045 1.00 45.35  ? 17   LEU B CD1 1 
ATOM   7030  C  CD2 . LEU B 1 17  ? 135.209 148.806 172.826 1.00 45.35  ? 17   LEU B CD2 1 
ATOM   7031  N  N   . VAL B 1 18  ? 131.641 151.896 175.466 1.00 45.00  ? 18   VAL B N   1 
ATOM   7032  C  CA  . VAL B 1 18  ? 131.005 152.981 176.194 1.00 45.00  ? 18   VAL B CA  1 
ATOM   7033  C  C   . VAL B 1 18  ? 130.065 152.374 177.226 1.00 45.00  ? 18   VAL B C   1 
ATOM   7034  O  O   . VAL B 1 18  ? 129.678 151.204 177.141 1.00 45.00  ? 18   VAL B O   1 
ATOM   7035  C  CB  . VAL B 1 18  ? 130.251 153.946 175.259 1.00 45.00  ? 18   VAL B CB  1 
ATOM   7036  C  CG1 . VAL B 1 18  ? 131.220 154.612 174.299 1.00 45.00  ? 18   VAL B CG1 1 
ATOM   7037  C  CG2 . VAL B 1 18  ? 129.163 153.206 174.501 1.00 45.00  ? 18   VAL B CG2 1 
ATOM   7038  N  N   . HIS B 1 19  ? 129.713 153.189 178.224 1.00 44.79  ? 19   HIS B N   1 
ATOM   7039  C  CA  . HIS B 1 19  ? 128.859 152.791 179.342 1.00 44.79  ? 19   HIS B CA  1 
ATOM   7040  C  C   . HIS B 1 19  ? 129.555 151.769 180.235 1.00 44.79  ? 19   HIS B C   1 
ATOM   7041  O  O   . HIS B 1 19  ? 130.379 150.976 179.771 1.00 44.79  ? 19   HIS B O   1 
ATOM   7042  C  CB  . HIS B 1 19  ? 127.515 152.247 178.847 1.00 44.79  ? 19   HIS B CB  1 
ATOM   7043  C  CG  . HIS B 1 19  ? 126.418 152.338 179.860 1.00 44.79  ? 19   HIS B CG  1 
ATOM   7044  N  ND1 . HIS B 1 19  ? 125.786 153.523 180.169 1.00 44.79  ? 19   HIS B ND1 1 
ATOM   7045  C  CD2 . HIS B 1 19  ? 125.837 151.390 180.634 1.00 44.79  ? 19   HIS B CD2 1 
ATOM   7046  C  CE1 . HIS B 1 19  ? 124.866 153.303 181.090 1.00 44.79  ? 19   HIS B CE1 1 
ATOM   7047  N  NE2 . HIS B 1 19  ? 124.876 152.016 181.389 1.00 44.79  ? 19   HIS B NE2 1 
ATOM   7048  N  N   . ARG B 1 20  ? 129.226 151.783 181.523 1.00 42.45  ? 20   ARG B N   1 
ATOM   7049  C  CA  . ARG B 1 20  ? 129.926 150.963 182.496 1.00 42.45  ? 20   ARG B CA  1 
ATOM   7050  C  C   . ARG B 1 20  ? 129.392 149.531 182.491 1.00 42.45  ? 20   ARG B C   1 
ATOM   7051  O  O   . ARG B 1 20  ? 128.513 149.162 181.707 1.00 42.45  ? 20   ARG B O   1 
ATOM   7052  C  CB  . ARG B 1 20  ? 129.805 151.579 183.886 1.00 42.45  ? 20   ARG B CB  1 
ATOM   7053  C  CG  . ARG B 1 20  ? 130.505 152.915 184.049 1.00 42.45  ? 20   ARG B CG  1 
ATOM   7054  C  CD  . ARG B 1 20  ? 130.273 153.473 185.443 1.00 42.45  ? 20   ARG B CD  1 
ATOM   7055  N  NE  . ARG B 1 20  ? 131.087 154.651 185.710 1.00 42.45  ? 20   ARG B NE  1 
ATOM   7056  C  CZ  . ARG B 1 20  ? 131.093 155.311 186.859 1.00 42.45  ? 20   ARG B CZ  1 
ATOM   7057  N  NH1 . ARG B 1 20  ? 130.332 154.936 187.875 1.00 42.45  ? 20   ARG B NH1 1 
ATOM   7058  N  NH2 . ARG B 1 20  ? 131.880 156.374 186.994 1.00 42.45  ? 20   ARG B NH2 1 
ATOM   7059  N  N   . ASP B 1 21  ? 129.940 148.716 183.386 1.00 55.79  ? 21   ASP B N   1 
ATOM   7060  C  CA  . ASP B 1 21  ? 129.583 147.325 183.599 1.00 55.79  ? 21   ASP B CA  1 
ATOM   7061  C  C   . ASP B 1 21  ? 128.486 147.209 184.647 1.00 55.79  ? 21   ASP B C   1 
ATOM   7062  O  O   . ASP B 1 21  ? 128.234 148.151 185.404 1.00 55.79  ? 21   ASP B O   1 
ATOM   7063  C  CB  . ASP B 1 21  ? 130.817 146.526 184.034 1.00 55.79  ? 21   ASP B CB  1 
ATOM   7064  C  CG  . ASP B 1 21  ? 131.875 146.454 182.951 1.00 55.79  ? 21   ASP B CG  1 
ATOM   7065  O  OD1 . ASP B 1 21  ? 131.652 147.027 181.863 1.00 55.79  ? 21   ASP B OD1 1 
ATOM   7066  O  OD2 . ASP B 1 21  ? 132.927 145.823 183.183 1.00 55.79  ? 21   ASP B OD2 1 
ATOM   7067  N  N   . PRO B 1 22  ? 127.793 146.066 184.705 1.00 68.28  ? 22   PRO B N   1 
ATOM   7068  C  CA  . PRO B 1 22  ? 126.680 145.934 185.665 1.00 68.28  ? 22   PRO B CA  1 
ATOM   7069  C  C   . PRO B 1 22  ? 127.052 146.176 187.123 1.00 68.28  ? 22   PRO B C   1 
ATOM   7070  O  O   . PRO B 1 22  ? 126.256 146.779 187.854 1.00 68.28  ? 22   PRO B O   1 
ATOM   7071  C  CB  . PRO B 1 22  ? 126.205 144.498 185.424 1.00 68.28  ? 22   PRO B CB  1 
ATOM   7072  C  CG  . PRO B 1 22  ? 126.504 144.252 183.992 1.00 68.28  ? 22   PRO B CG  1 
ATOM   7073  C  CD  . PRO B 1 22  ? 127.798 144.967 183.721 1.00 68.28  ? 22   PRO B CD  1 
ATOM   7074  N  N   . LEU B 1 23  ? 128.245 145.743 187.564 1.00 72.87  ? 23   LEU B N   1 
ATOM   7075  C  CA  . LEU B 1 23  ? 128.679 145.910 188.952 1.00 72.87  ? 23   LEU B CA  1 
ATOM   7076  C  C   . LEU B 1 23  ? 127.654 145.354 189.934 1.00 72.87  ? 23   LEU B C   1 
ATOM   7077  O  O   . LEU B 1 23  ? 126.809 146.106 190.439 1.00 72.87  ? 23   LEU B O   1 
ATOM   7078  C  CB  . LEU B 1 23  ? 128.971 147.370 189.302 1.00 72.87  ? 23   LEU B CB  1 
ATOM   7079  C  CG  . LEU B 1 23  ? 129.547 147.429 190.725 1.00 72.87  ? 23   LEU B CG  1 
ATOM   7080  C  CD1 . LEU B 1 23  ? 130.958 146.858 190.760 1.00 72.87  ? 23   LEU B CD1 1 
ATOM   7081  C  CD2 . LEU B 1 23  ? 129.499 148.820 191.335 1.00 72.87  ? 23   LEU B CD2 1 
ATOM   7082  N  N   . PRO B 1 24  ? 127.666 144.050 190.205 1.00 88.38  ? 24   PRO B N   1 
ATOM   7083  C  CA  . PRO B 1 24  ? 126.562 143.443 190.963 1.00 88.38  ? 24   PRO B CA  1 
ATOM   7084  C  C   . PRO B 1 24  ? 126.445 143.963 192.388 1.00 88.38  ? 24   PRO B C   1 
ATOM   7085  O  O   . PRO B 1 24  ? 126.561 143.202 193.354 1.00 88.38  ? 24   PRO B O   1 
ATOM   7086  C  CB  . PRO B 1 24  ? 126.914 141.948 190.962 1.00 88.38  ? 24   PRO B CB  1 
ATOM   7087  C  CG  . PRO B 1 24  ? 127.999 141.781 189.934 1.00 88.38  ? 24   PRO B CG  1 
ATOM   7088  C  CD  . PRO B 1 24  ? 128.724 143.080 189.887 1.00 88.38  ? 24   PRO B CD  1 
ATOM   7089  N  N   . GLY B 1 25  ? 126.222 145.271 192.519 1.00 92.56  ? 25   GLY B N   1 
ATOM   7090  C  CA  . GLY B 1 25  ? 125.835 145.882 193.783 1.00 92.56  ? 25   GLY B CA  1 
ATOM   7091  C  C   . GLY B 1 25  ? 124.953 147.093 193.509 1.00 92.56  ? 25   GLY B C   1 
ATOM   7092  O  O   . GLY B 1 25  ? 125.457 148.215 193.391 1.00 92.56  ? 25   GLY B O   1 
ATOM   7093  N  N   . ALA B 1 26  ? 123.638 146.878 193.448 1.00 108.06 ? 26   ALA B N   1 
ATOM   7094  C  CA  . ALA B 1 26  ? 122.682 147.914 193.068 1.00 108.06 ? 26   ALA B CA  1 
ATOM   7095  C  C   . ALA B 1 26  ? 121.261 147.369 193.107 1.00 108.06 ? 26   ALA B C   1 
ATOM   7096  O  O   . ALA B 1 26  ? 121.066 146.151 193.177 1.00 108.06 ? 26   ALA B O   1 
ATOM   7097  C  CB  . ALA B 1 26  ? 122.987 148.455 191.668 1.00 108.06 ? 26   ALA B CB  1 
ATOM   7098  N  N   . GLN B 1 27  ? 120.269 148.262 193.054 1.00 123.14 ? 27   GLN B N   1 
ATOM   7099  C  CA  . GLN B 1 27  ? 118.870 147.871 192.913 1.00 123.14 ? 27   GLN B CA  1 
ATOM   7100  C  C   . GLN B 1 27  ? 118.446 146.867 193.978 1.00 123.14 ? 27   GLN B C   1 
ATOM   7101  O  O   . GLN B 1 27  ? 118.097 145.726 193.661 1.00 123.14 ? 27   GLN B O   1 
ATOM   7102  C  CB  . GLN B 1 27  ? 118.613 147.301 191.517 1.00 123.14 ? 27   GLN B CB  1 
ATOM   7103  N  N   . GLN B 1 28  ? 118.485 147.280 195.247 1.00 129.01 ? 28   GLN B N   1 
ATOM   7104  C  CA  . GLN B 1 28  ? 118.133 146.399 196.356 1.00 129.01 ? 28   GLN B CA  1 
ATOM   7105  C  C   . GLN B 1 28  ? 116.670 145.971 196.340 1.00 129.01 ? 28   GLN B C   1 
ATOM   7106  O  O   . GLN B 1 28  ? 116.281 145.145 197.173 1.00 129.01 ? 28   GLN B O   1 
ATOM   7107  C  CB  . GLN B 1 28  ? 118.457 147.082 197.684 1.00 129.01 ? 28   GLN B CB  1 
ATOM   7108  N  N   . THR B 1 29  ? 115.855 146.509 195.433 1.00 135.48 ? 29   THR B N   1 
ATOM   7109  C  CA  . THR B 1 29  ? 114.480 146.051 195.298 1.00 135.48 ? 29   THR B CA  1 
ATOM   7110  C  C   . THR B 1 29  ? 114.453 144.623 194.766 1.00 135.48 ? 29   THR B C   1 
ATOM   7111  O  O   . THR B 1 29  ? 115.458 144.100 194.276 1.00 135.48 ? 29   THR B O   1 
ATOM   7112  C  CB  . THR B 1 29  ? 113.696 146.975 194.364 1.00 135.48 ? 29   THR B CB  1 
ATOM   7113  N  N   . VAL B 1 30  ? 113.286 143.991 194.861 1.00 138.09 ? 30   VAL B N   1 
ATOM   7114  C  CA  . VAL B 1 30  ? 113.139 142.593 194.476 1.00 138.09 ? 30   VAL B CA  1 
ATOM   7115  C  C   . VAL B 1 30  ? 112.894 142.489 192.976 1.00 138.09 ? 30   VAL B C   1 
ATOM   7116  O  O   . VAL B 1 30  ? 111.746 142.534 192.519 1.00 138.09 ? 30   VAL B O   1 
ATOM   7117  C  CB  . VAL B 1 30  ? 112.004 141.915 195.264 1.00 138.09 ? 30   VAL B CB  1 
ATOM   7118  N  N   . ASN B 1 31  ? 113.969 142.354 192.202 1.00 139.88 ? 31   ASN B N   1 
ATOM   7119  C  CA  . ASN B 1 31  ? 113.827 142.123 190.771 1.00 139.88 ? 31   ASN B CA  1 
ATOM   7120  C  C   . ASN B 1 31  ? 113.293 140.718 190.525 1.00 139.88 ? 31   ASN B C   1 
ATOM   7121  O  O   . ASN B 1 31  ? 113.859 139.733 191.010 1.00 139.88 ? 31   ASN B O   1 
ATOM   7122  C  CB  . ASN B 1 31  ? 115.169 142.317 190.067 1.00 139.88 ? 31   ASN B CB  1 
ATOM   7123  N  N   . THR B 1 32  ? 112.192 140.634 189.774 1.00 136.75 ? 32   THR B N   1 
ATOM   7124  C  CA  . THR B 1 32  ? 111.461 139.384 189.539 1.00 136.75 ? 32   THR B CA  1 
ATOM   7125  C  C   . THR B 1 32  ? 111.008 138.733 190.844 1.00 136.75 ? 32   THR B C   1 
ATOM   7126  O  O   . THR B 1 32  ? 110.689 137.539 190.866 1.00 136.75 ? 32   THR B O   1 
ATOM   7127  C  CB  . THR B 1 32  ? 112.285 138.392 188.710 1.00 136.75 ? 32   THR B CB  1 
ATOM   7128  N  N   . VAL B 1 33  ? 110.964 139.521 191.921 1.00 136.76 ? 33   VAL B N   1 
ATOM   7129  C  CA  . VAL B 1 33  ? 110.549 139.091 193.254 1.00 136.76 ? 33   VAL B CA  1 
ATOM   7130  C  C   . VAL B 1 33  ? 111.144 137.738 193.623 1.00 136.76 ? 33   VAL B C   1 
ATOM   7131  O  O   . VAL B 1 33  ? 110.417 136.828 194.037 1.00 136.76 ? 33   VAL B O   1 
ATOM   7132  C  CB  . VAL B 1 33  ? 109.013 139.048 193.355 1.00 136.76 ? 33   VAL B CB  1 
ATOM   7133  N  N   . VAL B 1 34  ? 112.464 137.609 193.497 1.00 134.91 ? 34   VAL B N   1 
ATOM   7134  C  CA  . VAL B 1 34  ? 113.180 136.373 193.818 1.00 134.91 ? 34   VAL B CA  1 
ATOM   7135  C  C   . VAL B 1 34  ? 112.526 135.209 193.083 1.00 134.91 ? 34   VAL B C   1 
ATOM   7136  O  O   . VAL B 1 34  ? 111.841 134.392 193.716 1.00 134.91 ? 34   VAL B O   1 
ATOM   7137  C  CB  . VAL B 1 34  ? 113.218 136.123 195.334 1.00 134.91 ? 34   VAL B CB  1 
ATOM   7138  N  N   . PRO B 1 35  ? 112.704 135.102 191.767 1.00 131.46 ? 35   PRO B N   1 
ATOM   7139  C  CA  . PRO B 1 35  ? 111.888 134.180 190.958 1.00 131.46 ? 35   PRO B CA  1 
ATOM   7140  C  C   . PRO B 1 35  ? 111.935 132.763 191.499 1.00 131.46 ? 35   PRO B C   1 
ATOM   7141  O  O   . PRO B 1 35  ? 112.996 132.285 191.929 1.00 131.46 ? 35   PRO B O   1 
ATOM   7142  C  CB  . PRO B 1 35  ? 112.531 134.268 189.564 1.00 131.46 ? 35   PRO B CB  1 
ATOM   7143  C  CG  . PRO B 1 35  ? 113.895 134.845 189.799 1.00 131.46 ? 35   PRO B CG  1 
ATOM   7144  C  CD  . PRO B 1 35  ? 113.742 135.767 190.965 1.00 131.46 ? 35   PRO B CD  1 
ATOM   7145  N  N   . PRO B 1 36  ? 110.792 132.069 191.507 1.00 126.40 ? 36   PRO B N   1 
ATOM   7146  C  CA  . PRO B 1 36  ? 110.711 130.772 192.204 1.00 126.40 ? 36   PRO B CA  1 
ATOM   7147  C  C   . PRO B 1 36  ? 111.709 129.734 191.721 1.00 126.40 ? 36   PRO B C   1 
ATOM   7148  O  O   . PRO B 1 36  ? 112.214 128.955 192.536 1.00 126.40 ? 36   PRO B O   1 
ATOM   7149  C  CB  . PRO B 1 36  ? 109.267 130.330 191.933 1.00 126.40 ? 36   PRO B CB  1 
ATOM   7150  C  CG  . PRO B 1 36  ? 108.521 131.598 191.694 1.00 126.40 ? 36   PRO B CG  1 
ATOM   7151  C  CD  . PRO B 1 36  ? 109.484 132.510 190.994 1.00 126.40 ? 36   PRO B CD  1 
ATOM   7152  N  N   . SER B 1 37  ? 112.001 129.691 190.420 1.00 122.68 ? 37   SER B N   1 
ATOM   7153  C  CA  . SER B 1 37  ? 112.944 128.703 189.907 1.00 122.68 ? 37   SER B CA  1 
ATOM   7154  C  C   . SER B 1 37  ? 114.328 128.903 190.515 1.00 122.68 ? 37   SER B C   1 
ATOM   7155  O  O   . SER B 1 37  ? 114.932 127.964 191.046 1.00 122.68 ? 37   SER B O   1 
ATOM   7156  C  CB  . SER B 1 37  ? 113.004 128.782 188.381 1.00 122.68 ? 37   SER B CB  1 
ATOM   7157  O  OG  . SER B 1 37  ? 113.402 130.072 187.953 1.00 122.68 ? 37   SER B OG  1 
ATOM   7158  N  N   . LEU B 1 38  ? 114.839 130.135 190.453 1.00 120.70 ? 38   LEU B N   1 
ATOM   7159  C  CA  . LEU B 1 38  ? 116.169 130.421 190.981 1.00 120.70 ? 38   LEU B CA  1 
ATOM   7160  C  C   . LEU B 1 38  ? 116.226 130.196 192.487 1.00 120.70 ? 38   LEU B C   1 
ATOM   7161  O  O   . LEU B 1 38  ? 117.182 129.604 193.003 1.00 120.70 ? 38   LEU B O   1 
ATOM   7162  C  CB  . LEU B 1 38  ? 116.569 131.856 190.636 1.00 120.70 ? 38   LEU B CB  1 
ATOM   7163  C  CG  . LEU B 1 38  ? 118.030 132.235 190.881 1.00 120.70 ? 38   LEU B CG  1 
ATOM   7164  C  CD1 . LEU B 1 38  ? 118.957 131.372 190.040 1.00 120.70 ? 38   LEU B CD1 1 
ATOM   7165  C  CD2 . LEU B 1 38  ? 118.254 133.711 190.593 1.00 120.70 ? 38   LEU B CD2 1 
ATOM   7166  N  N   . SER B 1 39  ? 115.209 130.671 193.210 1.00 122.20 ? 39   SER B N   1 
ATOM   7167  C  CA  . SER B 1 39  ? 115.198 130.523 194.662 1.00 122.20 ? 39   SER B CA  1 
ATOM   7168  C  C   . SER B 1 39  ? 115.156 129.054 195.063 1.00 122.20 ? 39   SER B C   1 
ATOM   7169  O  O   . SER B 1 39  ? 115.891 128.621 195.958 1.00 122.20 ? 39   SER B O   1 
ATOM   7170  C  CB  . SER B 1 39  ? 114.010 131.281 195.255 1.00 122.20 ? 39   SER B CB  1 
ATOM   7171  O  OG  . SER B 1 39  ? 113.966 131.141 196.665 1.00 122.20 ? 39   SER B OG  1 
ATOM   7172  N  N   . ALA B 1 40  ? 114.303 128.270 194.401 1.00 120.04 ? 40   ALA B N   1 
ATOM   7173  C  CA  . ALA B 1 40  ? 114.208 126.847 194.707 1.00 120.04 ? 40   ALA B CA  1 
ATOM   7174  C  C   . ALA B 1 40  ? 115.509 126.127 194.378 1.00 120.04 ? 40   ALA B C   1 
ATOM   7175  O  O   . ALA B 1 40  ? 115.961 125.264 195.140 1.00 120.04 ? 40   ALA B O   1 
ATOM   7176  C  CB  . ALA B 1 40  ? 113.037 126.225 193.947 1.00 120.04 ? 40   ALA B CB  1 
ATOM   7177  N  N   . HIS B 1 41  ? 116.129 126.470 193.244 1.00 115.19 ? 41   HIS B N   1 
ATOM   7178  C  CA  . HIS B 1 41  ? 117.389 125.837 192.872 1.00 115.19 ? 41   HIS B CA  1 
ATOM   7179  C  C   . HIS B 1 41  ? 118.477 126.144 193.893 1.00 115.19 ? 41   HIS B C   1 
ATOM   7180  O  O   . HIS B 1 41  ? 119.224 125.252 194.307 1.00 115.19 ? 41   HIS B O   1 
ATOM   7181  C  CB  . HIS B 1 41  ? 117.813 126.294 191.476 1.00 115.19 ? 41   HIS B CB  1 
ATOM   7182  C  CG  . HIS B 1 41  ? 119.122 125.723 191.027 1.00 115.19 ? 41   HIS B CG  1 
ATOM   7183  N  ND1 . HIS B 1 41  ? 120.211 126.510 190.717 1.00 115.19 ? 41   HIS B ND1 1 
ATOM   7184  C  CD2 . HIS B 1 41  ? 119.518 124.442 190.837 1.00 115.19 ? 41   HIS B CD2 1 
ATOM   7185  C  CE1 . HIS B 1 41  ? 121.220 125.738 190.355 1.00 115.19 ? 41   HIS B CE1 1 
ATOM   7186  N  NE2 . HIS B 1 41  ? 120.826 124.479 190.419 1.00 115.19 ? 41   HIS B NE2 1 
ATOM   7187  N  N   . CYS B 1 42  ? 118.572 127.406 194.318 1.00 116.89 ? 42   CYS B N   1 
ATOM   7188  C  CA  . CYS B 1 42  ? 119.571 127.781 195.315 1.00 116.89 ? 42   CYS B CA  1 
ATOM   7189  C  C   . CYS B 1 42  ? 119.314 127.075 196.642 1.00 116.89 ? 42   CYS B C   1 
ATOM   7190  O  O   . CYS B 1 42  ? 120.245 126.585 197.292 1.00 116.89 ? 42   CYS B O   1 
ATOM   7191  C  CB  . CYS B 1 42  ? 119.584 129.299 195.499 1.00 116.89 ? 42   CYS B CB  1 
ATOM   7192  S  SG  . CYS B 1 42  ? 120.084 130.228 194.031 1.00 116.89 ? 42   CYS B SG  1 
ATOM   7193  N  N   . LEU B 1 43  ? 118.048 127.014 197.062 1.00 114.57 ? 43   LEU B N   1 
ATOM   7194  C  CA  . LEU B 1 43  ? 117.718 126.370 198.329 1.00 114.57 ? 43   LEU B CA  1 
ATOM   7195  C  C   . LEU B 1 43  ? 118.052 124.884 198.296 1.00 114.57 ? 43   LEU B C   1 
ATOM   7196  O  O   . LEU B 1 43  ? 118.573 124.329 199.269 1.00 114.57 ? 43   LEU B O   1 
ATOM   7197  C  CB  . LEU B 1 43  ? 116.240 126.588 198.652 1.00 114.57 ? 43   LEU B CB  1 
ATOM   7198  C  CG  . LEU B 1 43  ? 115.907 127.992 199.156 1.00 114.57 ? 43   LEU B CG  1 
ATOM   7199  C  CD1 . LEU B 1 43  ? 114.408 128.166 199.345 1.00 114.57 ? 43   LEU B CD1 1 
ATOM   7200  C  CD2 . LEU B 1 43  ? 116.658 128.280 200.442 1.00 114.57 ? 43   LEU B CD2 1 
ATOM   7201  N  N   . LYS B 1 44  ? 117.756 124.223 197.175 1.00 113.08 ? 44   LYS B N   1 
ATOM   7202  C  CA  . LYS B 1 44  ? 118.069 122.803 197.047 1.00 113.08 ? 44   LYS B CA  1 
ATOM   7203  C  C   . LYS B 1 44  ? 119.575 122.578 196.981 1.00 113.08 ? 44   LYS B C   1 
ATOM   7204  O  O   . LYS B 1 44  ? 120.093 121.594 197.523 1.00 113.08 ? 44   LYS B O   1 
ATOM   7205  C  CB  . LYS B 1 44  ? 117.367 122.232 195.813 1.00 113.08 ? 44   LYS B CB  1 
ATOM   7206  C  CG  . LYS B 1 44  ? 118.123 121.133 195.088 1.00 113.08 ? 44   LYS B CG  1 
ATOM   7207  C  CD  . LYS B 1 44  ? 117.394 120.729 193.815 1.00 113.08 ? 44   LYS B CD  1 
ATOM   7208  C  CE  . LYS B 1 44  ? 118.259 119.851 192.928 1.00 113.08 ? 44   LYS B CE  1 
ATOM   7209  N  NZ  . LYS B 1 44  ? 119.454 120.583 192.425 1.00 113.08 ? 44   LYS B NZ  1 
ATOM   7210  N  N   . MET B 1 45  ? 120.299 123.491 196.328 1.00 108.36 ? 45   MET B N   1 
ATOM   7211  C  CA  . MET B 1 45  ? 121.741 123.328 196.183 1.00 108.36 ? 45   MET B CA  1 
ATOM   7212  C  C   . MET B 1 45  ? 122.483 123.630 197.479 1.00 108.36 ? 45   MET B C   1 
ATOM   7213  O  O   . MET B 1 45  ? 123.604 123.148 197.676 1.00 108.36 ? 45   MET B O   1 
ATOM   7214  C  CB  . MET B 1 45  ? 122.252 124.229 195.059 1.00 108.36 ? 45   MET B CB  1 
ATOM   7215  C  CG  . MET B 1 45  ? 122.039 123.665 193.665 1.00 108.36 ? 45   MET B CG  1 
ATOM   7216  S  SD  . MET B 1 45  ? 123.133 122.279 193.310 1.00 108.36 ? 45   MET B SD  1 
ATOM   7217  C  CE  . MET B 1 45  ? 124.640 122.842 194.096 1.00 108.36 ? 45   MET B CE  1 
ATOM   7218  N  N   . ALA B 1 46  ? 121.885 124.431 198.364 1.00 106.56 ? 46   ALA B N   1 
ATOM   7219  C  CA  . ALA B 1 46  ? 122.553 124.787 199.612 1.00 106.56 ? 46   ALA B CA  1 
ATOM   7220  C  C   . ALA B 1 46  ? 122.799 123.556 200.479 1.00 106.56 ? 46   ALA B C   1 
ATOM   7221  O  O   . ALA B 1 46  ? 123.944 123.237 200.820 1.00 106.56 ? 46   ALA B O   1 
ATOM   7222  C  CB  . ALA B 1 46  ? 121.723 125.824 200.370 1.00 106.56 ? 46   ALA B CB  1 
ATOM   7223  N  N   . VAL B 1 47  ? 121.727 122.843 200.839 1.00 110.61 ? 47   VAL B N   1 
ATOM   7224  C  CA  . VAL B 1 47  ? 121.845 121.675 201.712 1.00 110.61 ? 47   VAL B CA  1 
ATOM   7225  C  C   . VAL B 1 47  ? 122.155 120.397 200.953 1.00 110.61 ? 47   VAL B C   1 
ATOM   7226  O  O   . VAL B 1 47  ? 122.023 119.306 201.523 1.00 110.61 ? 47   VAL B O   1 
ATOM   7227  C  CB  . VAL B 1 47  ? 120.562 121.482 202.543 1.00 110.61 ? 47   VAL B CB  1 
ATOM   7228  C  CG1 . VAL B 1 47  ? 120.351 122.668 203.469 1.00 110.61 ? 47   VAL B CG1 1 
ATOM   7229  C  CG2 . VAL B 1 47  ? 119.362 121.298 201.630 1.00 110.61 ? 47   VAL B CG2 1 
ATOM   7230  N  N   . MET B 1 48  ? 122.545 120.495 199.686 1.00 111.90 ? 48   MET B N   1 
ATOM   7231  C  CA  . MET B 1 48  ? 122.876 119.333 198.877 1.00 111.90 ? 48   MET B CA  1 
ATOM   7232  C  C   . MET B 1 48  ? 124.003 118.532 199.526 1.00 111.90 ? 48   MET B C   1 
ATOM   7233  O  O   . MET B 1 48  ? 125.029 119.116 199.907 1.00 111.90 ? 48   MET B O   1 
ATOM   7234  C  CB  . MET B 1 48  ? 123.289 119.770 197.474 1.00 111.90 ? 48   MET B CB  1 
ATOM   7235  C  CG  . MET B 1 48  ? 123.475 118.624 196.493 1.00 111.90 ? 48   MET B CG  1 
ATOM   7236  S  SD  . MET B 1 48  ? 121.914 117.930 195.922 1.00 111.90 ? 48   MET B SD  1 
ATOM   7237  C  CE  . MET B 1 48  ? 121.295 119.282 194.925 1.00 111.90 ? 48   MET B CE  1 
ATOM   7238  N  N   . PRO B 1 49  ? 123.849 117.219 199.685 1.00 111.32 ? 49   PRO B N   1 
ATOM   7239  C  CA  . PRO B 1 49  ? 124.950 116.402 200.207 1.00 111.32 ? 49   PRO B CA  1 
ATOM   7240  C  C   . PRO B 1 49  ? 126.181 116.494 199.315 1.00 111.32 ? 49   PRO B C   1 
ATOM   7241  O  O   . PRO B 1 49  ? 126.081 116.605 198.091 1.00 111.32 ? 49   PRO B O   1 
ATOM   7242  C  CB  . PRO B 1 49  ? 124.365 114.987 200.218 1.00 111.32 ? 49   PRO B CB  1 
ATOM   7243  C  CG  . PRO B 1 49  ? 122.896 115.195 200.352 1.00 111.32 ? 49   PRO B CG  1 
ATOM   7244  C  CD  . PRO B 1 49  ? 122.586 116.466 199.610 1.00 111.32 ? 49   PRO B CD  1 
ATOM   7245  N  N   . GLU B 1 50  ? 127.355 116.451 199.949 1.00 113.77 ? 50   GLU B N   1 
ATOM   7246  C  CA  . GLU B 1 50  ? 128.606 116.647 199.224 1.00 113.77 ? 50   GLU B CA  1 
ATOM   7247  C  C   . GLU B 1 50  ? 128.881 115.508 198.248 1.00 113.77 ? 50   GLU B C   1 
ATOM   7248  O  O   . GLU B 1 50  ? 129.545 115.706 197.224 1.00 113.77 ? 50   GLU B O   1 
ATOM   7249  C  CB  . GLU B 1 50  ? 129.760 116.794 200.217 1.00 113.77 ? 50   GLU B CB  1 
ATOM   7250  C  CG  . GLU B 1 50  ? 131.030 117.383 199.626 1.00 113.77 ? 50   GLU B CG  1 
ATOM   7251  C  CD  . GLU B 1 50  ? 132.054 116.322 199.273 1.00 113.77 ? 50   GLU B CD  1 
ATOM   7252  O  OE1 . GLU B 1 50  ? 131.753 115.122 199.445 1.00 113.77 ? 50   GLU B OE1 1 
ATOM   7253  O  OE2 . GLU B 1 50  ? 133.161 116.689 198.829 1.00 113.77 ? 50   GLU B OE2 1 
ATOM   7254  N  N   . GLU B 1 51  ? 128.386 114.306 198.552 1.00 116.15 ? 51   GLU B N   1 
ATOM   7255  C  CA  . GLU B 1 51  ? 128.688 113.148 197.714 1.00 116.15 ? 51   GLU B CA  1 
ATOM   7256  C  C   . GLU B 1 51  ? 128.093 113.300 196.318 1.00 116.15 ? 51   GLU B C   1 
ATOM   7257  O  O   . GLU B 1 51  ? 128.796 113.151 195.312 1.00 116.15 ? 51   GLU B O   1 
ATOM   7258  C  CB  . GLU B 1 51  ? 128.178 111.870 198.378 1.00 116.15 ? 51   GLU B CB  1 
ATOM   7259  C  CG  . GLU B 1 51  ? 128.246 110.645 197.481 1.00 116.15 ? 51   GLU B CG  1 
ATOM   7260  C  CD  . GLU B 1 51  ? 127.456 109.474 198.028 1.00 116.15 ? 51   GLU B CD  1 
ATOM   7261  O  OE1 . GLU B 1 51  ? 126.858 109.614 199.116 1.00 116.15 ? 51   GLU B OE1 1 
ATOM   7262  O  OE2 . GLU B 1 51  ? 127.432 108.412 197.370 1.00 116.15 ? 51   GLU B OE2 1 
ATOM   7263  N  N   . GLU B 1 52  ? 126.795 113.598 196.236 1.00 114.33 ? 52   GLU B N   1 
ATOM   7264  C  CA  . GLU B 1 52  ? 126.147 113.725 194.936 1.00 114.33 ? 52   GLU B CA  1 
ATOM   7265  C  C   . GLU B 1 52  ? 126.440 115.056 194.259 1.00 114.33 ? 52   GLU B C   1 
ATOM   7266  O  O   . GLU B 1 52  ? 126.074 115.231 193.091 1.00 114.33 ? 52   GLU B O   1 
ATOM   7267  C  CB  . GLU B 1 52  ? 124.637 113.526 195.074 1.00 114.33 ? 52   GLU B CB  1 
ATOM   7268  C  CG  . GLU B 1 52  ? 123.973 114.386 196.135 1.00 114.33 ? 52   GLU B CG  1 
ATOM   7269  C  CD  . GLU B 1 52  ? 122.462 114.257 196.115 1.00 114.33 ? 52   GLU B CD  1 
ATOM   7270  O  OE1 . GLU B 1 52  ? 121.940 113.504 195.266 1.00 114.33 ? 52   GLU B OE1 1 
ATOM   7271  O  OE2 . GLU B 1 52  ? 121.794 114.902 196.950 1.00 114.33 ? 52   GLU B OE2 1 
ATOM   7272  N  N   . LEU B 1 53  ? 127.084 115.993 194.960 1.00 109.34 ? 53   LEU B N   1 
ATOM   7273  C  CA  . LEU B 1 53  ? 127.498 117.239 194.325 1.00 109.34 ? 53   LEU B CA  1 
ATOM   7274  C  C   . LEU B 1 53  ? 128.488 116.986 193.198 1.00 109.34 ? 53   LEU B C   1 
ATOM   7275  O  O   . LEU B 1 53  ? 128.464 117.686 192.180 1.00 109.34 ? 53   LEU B O   1 
ATOM   7276  C  CB  . LEU B 1 53  ? 128.107 118.179 195.365 1.00 109.34 ? 53   LEU B CB  1 
ATOM   7277  C  CG  . LEU B 1 53  ? 128.472 119.581 194.878 1.00 109.34 ? 53   LEU B CG  1 
ATOM   7278  C  CD1 . LEU B 1 53  ? 127.220 120.402 194.649 1.00 109.34 ? 53   LEU B CD1 1 
ATOM   7279  C  CD2 . LEU B 1 53  ? 129.392 120.268 195.871 1.00 109.34 ? 53   LEU B CD2 1 
ATOM   7280  N  N   . TRP B 1 54  ? 129.366 115.995 193.364 1.00 110.14 ? 54   TRP B N   1 
ATOM   7281  C  CA  . TRP B 1 54  ? 130.325 115.656 192.319 1.00 110.14 ? 54   TRP B CA  1 
ATOM   7282  C  C   . TRP B 1 54  ? 129.613 115.177 191.060 1.00 110.14 ? 54   TRP B C   1 
ATOM   7283  O  O   . TRP B 1 54  ? 129.978 115.552 189.940 1.00 110.14 ? 54   TRP B O   1 
ATOM   7284  C  CB  . TRP B 1 54  ? 131.292 114.590 192.836 1.00 110.14 ? 54   TRP B CB  1 
ATOM   7285  C  CG  . TRP B 1 54  ? 132.019 115.001 194.078 1.00 110.14 ? 54   TRP B CG  1 
ATOM   7286  C  CD1 . TRP B 1 54  ? 131.812 114.528 195.341 1.00 110.14 ? 54   TRP B CD1 1 
ATOM   7287  C  CD2 . TRP B 1 54  ? 133.071 115.966 194.178 1.00 110.14 ? 54   TRP B CD2 1 
ATOM   7288  N  NE1 . TRP B 1 54  ? 132.670 115.141 196.222 1.00 110.14 ? 54   TRP B NE1 1 
ATOM   7289  C  CE2 . TRP B 1 54  ? 133.454 116.028 195.533 1.00 110.14 ? 54   TRP B CE2 1 
ATOM   7290  C  CE3 . TRP B 1 54  ? 133.728 116.784 193.254 1.00 110.14 ? 54   TRP B CE3 1 
ATOM   7291  C  CZ2 . TRP B 1 54  ? 134.462 116.875 195.985 1.00 110.14 ? 54   TRP B CZ2 1 
ATOM   7292  C  CZ3 . TRP B 1 54  ? 134.728 117.624 193.706 1.00 110.14 ? 54   TRP B CZ3 1 
ATOM   7293  C  CH2 . TRP B 1 54  ? 135.085 117.664 195.059 1.00 110.14 ? 54   TRP B CH2 1 
ATOM   7294  N  N   . LYS B 1 55  ? 128.586 114.340 191.228 1.00 113.03 ? 55   LYS B N   1 
ATOM   7295  C  CA  . LYS B 1 55  ? 127.851 113.829 190.077 1.00 113.03 ? 55   LYS B CA  1 
ATOM   7296  C  C   . LYS B 1 55  ? 126.961 114.896 189.454 1.00 113.03 ? 55   LYS B C   1 
ATOM   7297  O  O   . LYS B 1 55  ? 126.736 114.882 188.238 1.00 113.03 ? 55   LYS B O   1 
ATOM   7298  C  CB  . LYS B 1 55  ? 127.013 112.617 190.485 1.00 113.03 ? 55   LYS B CB  1 
ATOM   7299  C  CG  . LYS B 1 55  ? 127.829 111.392 190.858 1.00 113.03 ? 55   LYS B CG  1 
ATOM   7300  C  CD  . LYS B 1 55  ? 126.933 110.257 191.326 1.00 113.03 ? 55   LYS B CD  1 
ATOM   7301  C  CE  . LYS B 1 55  ? 127.692 108.942 191.385 1.00 113.03 ? 55   LYS B CE  1 
ATOM   7302  N  NZ  . LYS B 1 55  ? 126.843 107.829 191.893 1.00 113.03 ? 55   LYS B NZ  1 
ATOM   7303  N  N   . THR B 1 56  ? 126.440 115.820 190.266 1.00 108.51 ? 56   THR B N   1 
ATOM   7304  C  CA  . THR B 1 56  ? 125.515 116.823 189.749 1.00 108.51 ? 56   THR B CA  1 
ATOM   7305  C  C   . THR B 1 56  ? 126.178 117.706 188.698 1.00 108.51 ? 56   THR B C   1 
ATOM   7306  O  O   . THR B 1 56  ? 125.586 117.985 187.648 1.00 108.51 ? 56   THR B O   1 
ATOM   7307  C  CB  . THR B 1 56  ? 124.973 117.676 190.897 1.00 108.51 ? 56   THR B CB  1 
ATOM   7308  O  OG1 . THR B 1 56  ? 124.199 116.856 191.780 1.00 108.51 ? 56   THR B OG1 1 
ATOM   7309  C  CG2 . THR B 1 56  ? 124.097 118.800 190.363 1.00 108.51 ? 56   THR B CG2 1 
ATOM   7310  N  N   . PHE B 1 57  ? 127.407 118.146 188.955 1.00 106.79 ? 57   PHE B N   1 
ATOM   7311  C  CA  . PHE B 1 57  ? 128.119 119.036 188.050 1.00 106.79 ? 57   PHE B CA  1 
ATOM   7312  C  C   . PHE B 1 57  ? 129.243 118.340 187.295 1.00 106.79 ? 57   PHE B C   1 
ATOM   7313  O  O   . PHE B 1 57  ? 130.049 119.018 186.649 1.00 106.79 ? 57   PHE B O   1 
ATOM   7314  C  CB  . PHE B 1 57  ? 128.669 120.237 188.820 1.00 106.79 ? 57   PHE B CB  1 
ATOM   7315  C  CG  . PHE B 1 57  ? 127.606 121.160 189.332 1.00 106.79 ? 57   PHE B CG  1 
ATOM   7316  C  CD1 . PHE B 1 57  ? 127.081 122.151 188.521 1.00 106.79 ? 57   PHE B CD1 1 
ATOM   7317  C  CD2 . PHE B 1 57  ? 127.122 121.031 190.622 1.00 106.79 ? 57   PHE B CD2 1 
ATOM   7318  C  CE1 . PHE B 1 57  ? 126.099 123.001 188.989 1.00 106.79 ? 57   PHE B CE1 1 
ATOM   7319  C  CE2 . PHE B 1 57  ? 126.141 121.877 191.095 1.00 106.79 ? 57   PHE B CE2 1 
ATOM   7320  C  CZ  . PHE B 1 57  ? 125.628 122.862 190.277 1.00 106.79 ? 57   PHE B CZ  1 
ATOM   7321  N  N   . ASP B 1 58  ? 129.311 117.010 187.357 1.00 111.18 ? 58   ASP B N   1 
ATOM   7322  C  CA  . ASP B 1 58  ? 130.332 116.233 186.653 1.00 111.18 ? 58   ASP B CA  1 
ATOM   7323  C  C   . ASP B 1 58  ? 131.733 116.711 187.027 1.00 111.18 ? 58   ASP B C   1 
ATOM   7324  O  O   . ASP B 1 58  ? 132.564 117.021 186.171 1.00 111.18 ? 58   ASP B O   1 
ATOM   7325  C  CB  . ASP B 1 58  ? 130.117 116.292 185.140 1.00 111.18 ? 58   ASP B CB  1 
ATOM   7326  C  CG  . ASP B 1 58  ? 128.839 115.604 184.705 1.00 111.18 ? 58   ASP B CG  1 
ATOM   7327  O  OD1 . ASP B 1 58  ? 128.404 114.659 185.396 1.00 111.18 ? 58   ASP B OD1 1 
ATOM   7328  O  OD2 . ASP B 1 58  ? 128.267 116.010 183.671 1.00 111.18 ? 58   ASP B OD2 1 
ATOM   7329  N  N   . THR B 1 59  ? 131.988 116.779 188.329 1.00 109.27 ? 59   THR B N   1 
ATOM   7330  C  CA  . THR B 1 59  ? 133.242 117.293 188.858 1.00 109.27 ? 59   THR B CA  1 
ATOM   7331  C  C   . THR B 1 59  ? 133.916 116.233 189.715 1.00 109.27 ? 59   THR B C   1 
ATOM   7332  O  O   . THR B 1 59  ? 133.248 115.478 190.428 1.00 109.27 ? 59   THR B O   1 
ATOM   7333  C  CB  . THR B 1 59  ? 133.010 118.564 189.683 1.00 109.27 ? 59   THR B CB  1 
ATOM   7334  O  OG1 . THR B 1 59  ? 132.233 119.493 188.917 1.00 109.27 ? 59   THR B OG1 1 
ATOM   7335  C  CG2 . THR B 1 59  ? 134.335 119.211 190.059 1.00 109.27 ? 59   THR B CG2 1 
ATOM   7336  N  N   . HIS B 1 60  ? 135.242 116.178 189.636 1.00 108.51 ? 60   HIS B N   1 
ATOM   7337  C  CA  . HIS B 1 60  ? 136.053 115.281 190.435 1.00 108.51 ? 60   HIS B CA  1 
ATOM   7338  C  C   . HIS B 1 60  ? 136.821 116.065 191.496 1.00 108.51 ? 60   HIS B C   1 
ATOM   7339  O  O   . HIS B 1 60  ? 137.082 117.260 191.320 1.00 108.51 ? 60   HIS B O   1 
ATOM   7340  C  CB  . HIS B 1 60  ? 137.043 114.507 189.557 1.00 108.51 ? 60   HIS B CB  1 
ATOM   7341  C  CG  . HIS B 1 60  ? 136.534 114.227 188.178 1.00 108.51 ? 60   HIS B CG  1 
ATOM   7342  N  ND1 . HIS B 1 60  ? 135.363 113.538 187.943 1.00 108.51 ? 60   HIS B ND1 1 
ATOM   7343  C  CD2 . HIS B 1 60  ? 137.035 114.543 186.961 1.00 108.51 ? 60   HIS B CD2 1 
ATOM   7344  C  CE1 . HIS B 1 60  ? 135.166 113.442 186.641 1.00 108.51 ? 60   HIS B CE1 1 
ATOM   7345  N  NE2 . HIS B 1 60  ? 136.166 114.043 186.022 1.00 108.51 ? 60   HIS B NE2 1 
ATOM   7346  N  N   . PRO B 1 61  ? 137.176 115.431 192.617 1.00 108.68 ? 61   PRO B N   1 
ATOM   7347  C  CA  . PRO B 1 61  ? 137.937 116.152 193.650 1.00 108.68 ? 61   PRO B CA  1 
ATOM   7348  C  C   . PRO B 1 61  ? 139.250 116.725 193.150 1.00 108.68 ? 61   PRO B C   1 
ATOM   7349  O  O   . PRO B 1 61  ? 139.647 117.812 193.587 1.00 108.68 ? 61   PRO B O   1 
ATOM   7350  C  CB  . PRO B 1 61  ? 138.163 115.081 194.725 1.00 108.68 ? 61   PRO B CB  1 
ATOM   7351  C  CG  . PRO B 1 61  ? 137.031 114.131 194.548 1.00 108.68 ? 61   PRO B CG  1 
ATOM   7352  C  CD  . PRO B 1 61  ? 136.751 114.095 193.071 1.00 108.68 ? 61   PRO B CD  1 
ATOM   7353  N  N   . GLU B 1 62  ? 139.937 116.029 192.242 1.00 108.90 ? 62   GLU B N   1 
ATOM   7354  C  CA  . GLU B 1 62  ? 141.208 116.526 191.731 1.00 108.90 ? 62   GLU B CA  1 
ATOM   7355  C  C   . GLU B 1 62  ? 141.037 117.720 190.800 1.00 108.90 ? 62   GLU B C   1 
ATOM   7356  O  O   . GLU B 1 62  ? 142.012 118.435 190.547 1.00 108.90 ? 62   GLU B O   1 
ATOM   7357  C  CB  . GLU B 1 62  ? 141.959 115.406 191.011 1.00 108.90 ? 62   GLU B CB  1 
ATOM   7358  C  CG  . GLU B 1 62  ? 141.350 115.003 189.681 1.00 108.90 ? 62   GLU B CG  1 
ATOM   7359  C  CD  . GLU B 1 62  ? 140.398 113.831 189.808 1.00 108.90 ? 62   GLU B CD  1 
ATOM   7360  O  OE1 . GLU B 1 62  ? 139.999 113.506 190.946 1.00 108.90 ? 62   GLU B OE1 1 
ATOM   7361  O  OE2 . GLU B 1 62  ? 140.047 113.236 188.768 1.00 108.90 ? 62   GLU B OE2 1 
ATOM   7362  N  N   . GLY B 1 63  ? 139.828 117.954 190.287 1.00 108.12 ? 63   GLY B N   1 
ATOM   7363  C  CA  . GLY B 1 63  ? 139.562 119.080 189.415 1.00 108.12 ? 63   GLY B CA  1 
ATOM   7364  C  C   . GLY B 1 63  ? 139.036 118.629 188.062 1.00 108.12 ? 63   GLY B C   1 
ATOM   7365  O  O   . GLY B 1 63  ? 138.461 117.542 187.930 1.00 108.12 ? 63   GLY B O   1 
ATOM   7366  N  N   . LEU B 1 64  ? 139.247 119.477 187.058 1.00 106.60 ? 64   LEU B N   1 
ATOM   7367  C  CA  . LEU B 1 64  ? 138.772 119.225 185.706 1.00 106.60 ? 64   LEU B CA  1 
ATOM   7368  C  C   . LEU B 1 64  ? 139.934 119.318 184.730 1.00 106.60 ? 64   LEU B C   1 
ATOM   7369  O  O   . LEU B 1 64  ? 140.803 120.184 184.869 1.00 106.60 ? 64   LEU B O   1 
ATOM   7370  C  CB  . LEU B 1 64  ? 137.678 120.224 185.303 1.00 106.60 ? 64   LEU B CB  1 
ATOM   7371  C  CG  . LEU B 1 64  ? 136.426 120.305 186.178 1.00 106.60 ? 64   LEU B CG  1 
ATOM   7372  C  CD1 . LEU B 1 64  ? 135.371 121.178 185.519 1.00 106.60 ? 64   LEU B CD1 1 
ATOM   7373  C  CD2 . LEU B 1 64  ? 135.877 118.918 186.456 1.00 106.60 ? 64   LEU B CD2 1 
ATOM   7374  N  N   . ASN B 1 65  ? 139.943 118.430 183.739 1.00 108.00 ? 65   ASN B N   1 
ATOM   7375  C  CA  . ASN B 1 65  ? 140.944 118.487 182.688 1.00 108.00 ? 65   ASN B CA  1 
ATOM   7376  C  C   . ASN B 1 65  ? 140.402 119.299 181.511 1.00 108.00 ? 65   ASN B C   1 
ATOM   7377  O  O   . ASN B 1 65  ? 139.313 119.875 181.573 1.00 108.00 ? 65   ASN B O   1 
ATOM   7378  C  CB  . ASN B 1 65  ? 141.371 117.078 182.273 1.00 108.00 ? 65   ASN B CB  1 
ATOM   7379  C  CG  . ASN B 1 65  ? 140.198 116.185 181.915 1.00 108.00 ? 65   ASN B CG  1 
ATOM   7380  O  OD1 . ASN B 1 65  ? 139.062 116.643 181.810 1.00 108.00 ? 65   ASN B OD1 1 
ATOM   7381  N  ND2 . ASN B 1 65  ? 140.471 114.900 181.719 1.00 108.00 ? 65   ASN B ND2 1 
ATOM   7382  N  N   . GLN B 1 66  ? 141.174 119.354 180.425 1.00 104.98 ? 66   GLN B N   1 
ATOM   7383  C  CA  . GLN B 1 66  ? 140.835 120.210 179.293 1.00 104.98 ? 66   GLN B CA  1 
ATOM   7384  C  C   . GLN B 1 66  ? 139.504 119.829 178.657 1.00 104.98 ? 66   GLN B C   1 
ATOM   7385  O  O   . GLN B 1 66  ? 138.537 120.596 178.722 1.00 104.98 ? 66   GLN B O   1 
ATOM   7386  C  CB  . GLN B 1 66  ? 141.945 120.162 178.241 1.00 104.98 ? 66   GLN B CB  1 
ATOM   7387  N  N   . ALA B 1 67  ? 139.425 118.623 178.091 1.00 109.25 ? 67   ALA B N   1 
ATOM   7388  C  CA  . ALA B 1 67  ? 138.233 118.242 177.341 1.00 109.25 ? 67   ALA B CA  1 
ATOM   7389  C  C   . ALA B 1 67  ? 136.972 118.488 178.158 1.00 109.25 ? 67   ALA B C   1 
ATOM   7390  O  O   . ALA B 1 67  ? 135.973 119.001 177.640 1.00 109.25 ? 67   ALA B O   1 
ATOM   7391  C  CB  . ALA B 1 67  ? 138.327 116.776 176.915 1.00 109.25 ? 67   ALA B CB  1 
ATOM   7392  N  N   . GLU B 1 68  ? 137.030 118.197 179.459 1.00 109.39 ? 68   GLU B N   1 
ATOM   7393  C  CA  . GLU B 1 68  ? 135.894 118.464 180.332 1.00 109.39 ? 68   GLU B CA  1 
ATOM   7394  C  C   . GLU B 1 68  ? 135.604 119.958 180.444 1.00 109.39 ? 68   GLU B C   1 
ATOM   7395  O  O   . GLU B 1 68  ? 134.436 120.360 180.454 1.00 109.39 ? 68   GLU B O   1 
ATOM   7396  C  CB  . GLU B 1 68  ? 136.141 117.853 181.712 1.00 109.39 ? 68   GLU B CB  1 
ATOM   7397  C  CG  . GLU B 1 68  ? 134.871 117.439 182.437 1.00 109.39 ? 68   GLU B CG  1 
ATOM   7398  C  CD  . GLU B 1 68  ? 135.142 116.539 183.626 1.00 109.39 ? 68   GLU B CD  1 
ATOM   7399  O  OE1 . GLU B 1 68  ? 136.322 116.382 184.005 1.00 109.39 ? 68   GLU B OE1 1 
ATOM   7400  O  OE2 . GLU B 1 68  ? 134.173 115.969 184.168 1.00 109.39 ? 68   GLU B OE2 1 
ATOM   7401  N  N   . VAL B 1 69  ? 136.638 120.802 180.533 1.00 106.03 ? 69   VAL B N   1 
ATOM   7402  C  CA  . VAL B 1 69  ? 136.367 122.222 180.755 1.00 106.03 ? 69   VAL B CA  1 
ATOM   7403  C  C   . VAL B 1 69  ? 135.792 122.867 179.496 1.00 106.03 ? 69   VAL B C   1 
ATOM   7404  O  O   . VAL B 1 69  ? 134.854 123.668 179.578 1.00 106.03 ? 69   VAL B O   1 
ATOM   7405  C  CB  . VAL B 1 69  ? 137.610 122.972 181.283 1.00 106.03 ? 69   VAL B CB  1 
ATOM   7406  C  CG1 . VAL B 1 69  ? 138.716 123.083 180.251 1.00 106.03 ? 69   VAL B CG1 1 
ATOM   7407  C  CG2 . VAL B 1 69  ? 137.213 124.350 181.787 1.00 106.03 ? 69   VAL B CG2 1 
ATOM   7408  N  N   . GLU B 1 70  ? 136.317 122.527 178.311 1.00 107.34 ? 70   GLU B N   1 
ATOM   7409  C  CA  . GLU B 1 70  ? 135.673 123.025 177.093 1.00 107.34 ? 70   GLU B CA  1 
ATOM   7410  C  C   . GLU B 1 70  ? 134.279 122.435 176.895 1.00 107.34 ? 70   GLU B C   1 
ATOM   7411  O  O   . GLU B 1 70  ? 133.379 123.125 176.403 1.00 107.34 ? 70   GLU B O   1 
ATOM   7412  C  CB  . GLU B 1 70  ? 136.537 122.818 175.841 1.00 107.34 ? 70   GLU B CB  1 
ATOM   7413  C  CG  . GLU B 1 70  ? 137.731 123.785 175.681 1.00 107.34 ? 70   GLU B CG  1 
ATOM   7414  C  CD  . GLU B 1 70  ? 138.993 123.400 176.411 1.00 107.34 ? 70   GLU B CD  1 
ATOM   7415  O  OE1 . GLU B 1 70  ? 139.028 122.334 177.033 1.00 107.34 ? 70   GLU B OE1 1 
ATOM   7416  O  OE2 . GLU B 1 70  ? 139.969 124.180 176.356 1.00 107.34 ? 70   GLU B OE2 1 
ATOM   7417  N  N   . SER B 1 71  ? 134.064 121.173 177.277 1.00 106.21 ? 71   SER B N   1 
ATOM   7418  C  CA  . SER B 1 71  ? 132.718 120.614 177.181 1.00 106.21 ? 71   SER B CA  1 
ATOM   7419  C  C   . SER B 1 71  ? 131.745 121.380 178.071 1.00 106.21 ? 71   SER B C   1 
ATOM   7420  O  O   . SER B 1 71  ? 130.631 121.720 177.653 1.00 106.21 ? 71   SER B O   1 
ATOM   7421  C  CB  . SER B 1 71  ? 132.737 119.131 177.553 1.00 106.21 ? 71   SER B CB  1 
ATOM   7422  O  OG  . SER B 1 71  ? 131.435 118.577 177.500 1.00 106.21 ? 71   SER B OG  1 
ATOM   7423  N  N   . ALA B 1 72  ? 132.163 121.678 179.303 1.00 104.76 ? 72   ALA B N   1 
ATOM   7424  C  CA  . ALA B 1 72  ? 131.314 122.424 180.224 1.00 104.76 ? 72   ALA B CA  1 
ATOM   7425  C  C   . ALA B 1 72  ? 131.077 123.846 179.733 1.00 104.76 ? 72   ALA B C   1 
ATOM   7426  O  O   . ALA B 1 72  ? 129.969 124.376 179.869 1.00 104.76 ? 72   ALA B O   1 
ATOM   7427  C  CB  . ALA B 1 72  ? 131.934 122.432 181.620 1.00 104.76 ? 72   ALA B CB  1 
ATOM   7428  N  N   . ARG B 1 73  ? 132.107 124.485 179.173 1.00 101.96 ? 73   ARG B N   1 
ATOM   7429  C  CA  . ARG B 1 73  ? 131.937 125.833 178.640 1.00 101.96 ? 73   ARG B CA  1 
ATOM   7430  C  C   . ARG B 1 73  ? 130.958 125.843 177.474 1.00 101.96 ? 73   ARG B C   1 
ATOM   7431  O  O   . ARG B 1 73  ? 130.129 126.752 177.357 1.00 101.96 ? 73   ARG B O   1 
ATOM   7432  C  CB  . ARG B 1 73  ? 133.289 126.405 178.212 1.00 101.96 ? 73   ARG B CB  1 
ATOM   7433  C  CG  . ARG B 1 73  ? 133.230 127.846 177.733 1.00 101.96 ? 73   ARG B CG  1 
ATOM   7434  C  CD  . ARG B 1 73  ? 134.624 128.413 177.522 1.00 101.96 ? 73   ARG B CD  1 
ATOM   7435  N  NE  . ARG B 1 73  ? 135.536 128.024 178.591 1.00 101.96 ? 73   ARG B NE  1 
ATOM   7436  C  CZ  . ARG B 1 73  ? 136.846 128.227 178.570 1.00 101.96 ? 73   ARG B CZ  1 
ATOM   7437  N  NH1 . ARG B 1 73  ? 137.436 128.825 177.548 1.00 101.96 ? 73   ARG B NH1 1 
ATOM   7438  N  NH2 . ARG B 1 73  ? 137.582 127.822 179.601 1.00 101.96 ? 73   ARG B NH2 1 
ATOM   7439  N  N   . GLU B 1 74  ? 131.041 124.841 176.597 1.00 106.50 ? 74   GLU B N   1 
ATOM   7440  C  CA  . GLU B 1 74  ? 130.092 124.749 175.494 1.00 106.50 ? 74   GLU B CA  1 
ATOM   7441  C  C   . GLU B 1 74  ? 128.676 124.505 176.002 1.00 106.50 ? 74   GLU B C   1 
ATOM   7442  O  O   . GLU B 1 74  ? 127.715 125.079 175.476 1.00 106.50 ? 74   GLU B O   1 
ATOM   7443  C  CB  . GLU B 1 74  ? 130.518 123.643 174.530 1.00 106.50 ? 74   GLU B CB  1 
ATOM   7444  C  CG  . GLU B 1 74  ? 131.591 124.066 173.542 1.00 106.50 ? 74   GLU B CG  1 
ATOM   7445  C  CD  . GLU B 1 74  ? 131.448 123.381 172.198 1.00 106.50 ? 74   GLU B CD  1 
ATOM   7446  O  OE1 . GLU B 1 74  ? 130.941 122.241 172.161 1.00 106.50 ? 74   GLU B OE1 1 
ATOM   7447  O  OE2 . GLU B 1 74  ? 131.845 123.983 171.178 1.00 106.50 ? 74   GLU B OE2 1 
ATOM   7448  N  N   . GLN B 1 75  ? 128.527 123.658 177.023 1.00 104.66 ? 75   GLN B N   1 
ATOM   7449  C  CA  . GLN B 1 75  ? 127.191 123.326 177.510 1.00 104.66 ? 75   GLN B CA  1 
ATOM   7450  C  C   . GLN B 1 75  ? 126.549 124.498 178.246 1.00 104.66 ? 75   GLN B C   1 
ATOM   7451  O  O   . GLN B 1 75  ? 125.369 124.799 178.032 1.00 104.66 ? 75   GLN B O   1 
ATOM   7452  C  CB  . GLN B 1 75  ? 127.256 122.097 178.417 1.00 104.66 ? 75   GLN B CB  1 
ATOM   7453  C  CG  . GLN B 1 75  ? 125.981 121.838 179.203 1.00 104.66 ? 75   GLN B CG  1 
ATOM   7454  C  CD  . GLN B 1 75  ? 126.128 120.702 180.196 1.00 104.66 ? 75   GLN B CD  1 
ATOM   7455  O  OE1 . GLN B 1 75  ? 127.058 119.900 180.108 1.00 104.66 ? 75   GLN B OE1 1 
ATOM   7456  N  NE2 . GLN B 1 75  ? 125.207 120.628 181.150 1.00 104.66 ? 75   GLN B NE2 1 
ATOM   7457  N  N   . HIS B 1 76  ? 127.305 125.171 179.111 1.00 99.89  ? 76   HIS B N   1 
ATOM   7458  C  CA  . HIS B 1 76  ? 126.760 126.194 179.994 1.00 99.89  ? 76   HIS B CA  1 
ATOM   7459  C  C   . HIS B 1 76  ? 127.150 127.612 179.600 1.00 99.89  ? 76   HIS B C   1 
ATOM   7460  O  O   . HIS B 1 76  ? 126.900 128.543 180.372 1.00 99.89  ? 76   HIS B O   1 
ATOM   7461  C  CB  . HIS B 1 76  ? 127.203 125.929 181.436 1.00 99.89  ? 76   HIS B CB  1 
ATOM   7462  C  CG  . HIS B 1 76  ? 126.399 124.876 182.133 1.00 99.89  ? 76   HIS B CG  1 
ATOM   7463  N  ND1 . HIS B 1 76  ? 125.121 125.100 182.596 1.00 99.89  ? 76   HIS B ND1 1 
ATOM   7464  C  CD2 . HIS B 1 76  ? 126.694 123.593 182.451 1.00 99.89  ? 76   HIS B CD2 1 
ATOM   7465  C  CE1 . HIS B 1 76  ? 124.662 124.001 183.166 1.00 99.89  ? 76   HIS B CE1 1 
ATOM   7466  N  NE2 . HIS B 1 76  ? 125.597 123.072 183.092 1.00 99.89  ? 76   HIS B NE2 1 
ATOM   7467  N  N   . GLY B 1 77  ? 127.752 127.805 178.433 1.00 97.99  ? 77   GLY B N   1 
ATOM   7468  C  CA  . GLY B 1 77  ? 128.143 129.133 178.015 1.00 97.99  ? 77   GLY B CA  1 
ATOM   7469  C  C   . GLY B 1 77  ? 129.412 129.612 178.696 1.00 97.99  ? 77   GLY B C   1 
ATOM   7470  O  O   . GLY B 1 77  ? 130.180 128.845 179.285 1.00 97.99  ? 77   GLY B O   1 
ATOM   7471  N  N   . GLU B 1 78  ? 129.626 130.921 178.607 1.00 93.47  ? 78   GLU B N   1 
ATOM   7472  C  CA  . GLU B 1 78  ? 130.809 131.569 179.152 1.00 93.47  ? 78   GLU B CA  1 
ATOM   7473  C  C   . GLU B 1 78  ? 130.427 132.441 180.342 1.00 93.47  ? 78   GLU B C   1 
ATOM   7474  O  O   . GLU B 1 78  ? 129.294 132.919 180.445 1.00 93.47  ? 78   GLU B O   1 
ATOM   7475  C  CB  . GLU B 1 78  ? 131.508 132.416 178.083 1.00 93.47  ? 78   GLU B CB  1 
ATOM   7476  C  CG  . GLU B 1 78  ? 132.960 132.741 178.391 1.00 93.47  ? 78   GLU B CG  1 
ATOM   7477  C  CD  . GLU B 1 78  ? 133.659 133.428 177.235 1.00 93.47  ? 78   GLU B CD  1 
ATOM   7478  O  OE1 . GLU B 1 78  ? 132.991 133.715 176.219 1.00 93.47  ? 78   GLU B OE1 1 
ATOM   7479  O  OE2 . GLU B 1 78  ? 134.877 133.682 177.342 1.00 93.47  ? 78   GLU B OE2 1 
ATOM   7480  N  N   . ASN B 1 79  ? 131.389 132.646 181.244 1.00 88.12  ? 79   ASN B N   1 
ATOM   7481  C  CA  . ASN B 1 79  ? 131.163 133.410 182.472 1.00 88.12  ? 79   ASN B CA  1 
ATOM   7482  C  C   . ASN B 1 79  ? 131.210 134.908 182.167 1.00 88.12  ? 79   ASN B C   1 
ATOM   7483  O  O   . ASN B 1 79  ? 132.082 135.651 182.621 1.00 88.12  ? 79   ASN B O   1 
ATOM   7484  C  CB  . ASN B 1 79  ? 132.188 133.027 183.531 1.00 88.12  ? 79   ASN B CB  1 
ATOM   7485  C  CG  . ASN B 1 79  ? 131.877 133.631 184.887 1.00 88.12  ? 79   ASN B CG  1 
ATOM   7486  O  OD1 . ASN B 1 79  ? 130.715 133.846 185.231 1.00 88.12  ? 79   ASN B OD1 1 
ATOM   7487  N  ND2 . ASN B 1 79  ? 132.916 133.904 185.666 1.00 88.12  ? 79   ASN B ND2 1 
ATOM   7488  N  N   . LYS B 1 80  ? 130.231 135.351 181.381 1.00 91.83  ? 80   LYS B N   1 
ATOM   7489  C  CA  . LYS B 1 80  ? 130.108 136.751 181.005 1.00 91.83  ? 80   LYS B CA  1 
ATOM   7490  C  C   . LYS B 1 80  ? 128.633 137.093 180.849 1.00 91.83  ? 80   LYS B C   1 
ATOM   7491  O  O   . LYS B 1 80  ? 127.782 136.215 180.677 1.00 91.83  ? 80   LYS B O   1 
ATOM   7492  C  CB  . LYS B 1 80  ? 130.879 137.056 179.714 1.00 91.83  ? 80   LYS B CB  1 
ATOM   7493  C  CG  . LYS B 1 80  ? 132.371 137.266 179.907 1.00 91.83  ? 80   LYS B CG  1 
ATOM   7494  C  CD  . LYS B 1 80  ? 132.999 137.927 178.691 1.00 91.83  ? 80   LYS B CD  1 
ATOM   7495  C  CE  . LYS B 1 80  ? 133.311 136.909 177.608 1.00 91.83  ? 80   LYS B CE  1 
ATOM   7496  N  NZ  . LYS B 1 80  ? 134.456 137.339 176.758 1.00 91.83  ? 80   LYS B NZ  1 
ATOM   7497  N  N   . LEU B 1 81  ? 128.335 138.379 180.908 1.00 88.94  ? 81   LEU B N   1 
ATOM   7498  C  CA  . LEU B 1 81  ? 126.998 138.901 180.689 1.00 88.94  ? 81   LEU B CA  1 
ATOM   7499  C  C   . LEU B 1 81  ? 126.691 138.934 179.199 1.00 88.94  ? 81   LEU B C   1 
ATOM   7500  O  O   . LEU B 1 81  ? 127.605 138.962 178.369 1.00 88.94  ? 81   LEU B O   1 
ATOM   7501  C  CB  . LEU B 1 81  ? 126.875 140.310 181.282 1.00 88.94  ? 81   LEU B CB  1 
ATOM   7502  C  CG  . LEU B 1 81  ? 126.422 140.460 182.741 1.00 88.94  ? 81   LEU B CG  1 
ATOM   7503  C  CD1 . LEU B 1 81  ? 124.949 140.110 182.902 1.00 88.94  ? 81   LEU B CD1 1 
ATOM   7504  C  CD2 . LEU B 1 81  ? 127.281 139.633 183.690 1.00 88.94  ? 81   LEU B CD2 1 
ATOM   7505  N  N   . PRO B 1 82  ? 125.411 138.926 178.815 1.00 86.65  ? 82   PRO B N   1 
ATOM   7506  C  CA  . PRO B 1 82  ? 125.081 138.938 177.379 1.00 86.65  ? 82   PRO B CA  1 
ATOM   7507  C  C   . PRO B 1 82  ? 125.577 140.172 176.646 1.00 86.65  ? 82   PRO B C   1 
ATOM   7508  O  O   . PRO B 1 82  ? 125.695 140.134 175.415 1.00 86.65  ? 82   PRO B O   1 
ATOM   7509  C  CB  . PRO B 1 82  ? 123.547 138.858 177.370 1.00 86.65  ? 82   PRO B CB  1 
ATOM   7510  C  CG  . PRO B 1 82  ? 123.130 139.309 178.732 1.00 86.65  ? 82   PRO B CG  1 
ATOM   7511  C  CD  . PRO B 1 82  ? 124.202 138.806 179.646 1.00 86.65  ? 82   PRO B CD  1 
ATOM   7512  N  N   . ALA B 1 83  ? 125.872 141.258 177.354 1.00 86.26  ? 83   ALA B N   1 
ATOM   7513  C  CA  . ALA B 1 83  ? 126.372 142.479 176.738 1.00 86.26  ? 83   ALA B CA  1 
ATOM   7514  C  C   . ALA B 1 83  ? 127.892 142.520 176.637 1.00 86.26  ? 83   ALA B C   1 
ATOM   7515  O  O   . ALA B 1 83  ? 128.440 143.533 176.190 1.00 86.26  ? 83   ALA B O   1 
ATOM   7516  C  CB  . ALA B 1 83  ? 125.877 143.702 177.518 1.00 86.26  ? 83   ALA B CB  1 
ATOM   7517  N  N   . GLN B 1 84  ? 128.585 141.453 177.034 1.00 84.03  ? 84   GLN B N   1 
ATOM   7518  C  CA  . GLN B 1 84  ? 130.041 141.436 177.057 1.00 84.03  ? 84   GLN B CA  1 
ATOM   7519  C  C   . GLN B 1 84  ? 130.657 140.590 175.951 1.00 84.03  ? 84   GLN B C   1 
ATOM   7520  O  O   . GLN B 1 84  ? 131.885 140.584 175.811 1.00 84.03  ? 84   GLN B O   1 
ATOM   7521  C  CB  . GLN B 1 84  ? 130.540 140.936 178.418 1.00 84.03  ? 84   GLN B CB  1 
ATOM   7522  C  CG  . GLN B 1 84  ? 130.442 141.962 179.534 1.00 84.03  ? 84   GLN B CG  1 
ATOM   7523  C  CD  . GLN B 1 84  ? 131.418 143.108 179.359 1.00 84.03  ? 84   GLN B CD  1 
ATOM   7524  O  OE1 . GLN B 1 84  ? 132.526 142.925 178.855 1.00 84.03  ? 84   GLN B OE1 1 
ATOM   7525  N  NE2 . GLN B 1 84  ? 131.010 144.301 179.777 1.00 84.03  ? 84   GLN B NE2 1 
ATOM   7526  N  N   . GLN B 1 85  ? 129.852 139.879 175.163 1.00 85.54  ? 85   GLN B N   1 
ATOM   7527  C  CA  . GLN B 1 85  ? 130.388 139.052 174.090 1.00 85.54  ? 85   GLN B CA  1 
ATOM   7528  C  C   . GLN B 1 85  ? 130.534 139.881 172.823 1.00 85.54  ? 85   GLN B C   1 
ATOM   7529  O  O   . GLN B 1 85  ? 129.523 140.364 172.294 1.00 85.54  ? 85   GLN B O   1 
ATOM   7530  C  CB  . GLN B 1 85  ? 129.488 137.857 173.822 1.00 85.54  ? 85   GLN B CB  1 
ATOM   7531  C  CG  . GLN B 1 85  ? 129.593 136.753 174.858 1.00 85.54  ? 85   GLN B CG  1 
ATOM   7532  C  CD  . GLN B 1 85  ? 128.589 136.914 175.977 1.00 85.54  ? 85   GLN B CD  1 
ATOM   7533  O  OE1 . GLN B 1 85  ? 127.640 137.688 175.864 1.00 85.54  ? 85   GLN B OE1 1 
ATOM   7534  N  NE2 . GLN B 1 85  ? 128.792 136.184 177.067 1.00 85.54  ? 85   GLN B NE2 1 
ATOM   7535  N  N   . PRO B 1 86  ? 131.745 140.077 172.310 1.00 76.89  ? 86   PRO B N   1 
ATOM   7536  C  CA  . PRO B 1 86  ? 131.898 140.802 171.046 1.00 76.89  ? 86   PRO B CA  1 
ATOM   7537  C  C   . PRO B 1 86  ? 131.317 140.019 169.880 1.00 76.89  ? 86   PRO B C   1 
ATOM   7538  O  O   . PRO B 1 86  ? 131.329 138.786 169.857 1.00 76.89  ? 86   PRO B O   1 
ATOM   7539  C  CB  . PRO B 1 86  ? 133.416 140.963 170.909 1.00 76.89  ? 86   PRO B CB  1 
ATOM   7540  C  CG  . PRO B 1 86  ? 133.987 139.848 171.717 1.00 76.89  ? 86   PRO B CG  1 
ATOM   7541  C  CD  . PRO B 1 86  ? 133.037 139.632 172.860 1.00 76.89  ? 86   PRO B CD  1 
ATOM   7542  N  N   . SER B 1 87  ? 130.801 140.758 168.904 1.00 79.86  ? 87   SER B N   1 
ATOM   7543  C  CA  . SER B 1 87  ? 130.237 140.154 167.710 1.00 79.86  ? 87   SER B CA  1 
ATOM   7544  C  C   . SER B 1 87  ? 131.347 139.641 166.792 1.00 79.86  ? 87   SER B C   1 
ATOM   7545  O  O   . SER B 1 87  ? 132.477 140.133 166.839 1.00 79.86  ? 87   SER B O   1 
ATOM   7546  C  CB  . SER B 1 87  ? 129.374 141.165 166.963 1.00 79.86  ? 87   SER B CB  1 
ATOM   7547  O  OG  . SER B 1 87  ? 130.171 142.018 166.160 1.00 79.86  ? 87   SER B OG  1 
ATOM   7548  N  N   . PRO B 1 88  ? 131.051 138.646 165.957 1.00 82.32  ? 88   PRO B N   1 
ATOM   7549  C  CA  . PRO B 1 88  ? 132.055 138.172 164.998 1.00 82.32  ? 88   PRO B CA  1 
ATOM   7550  C  C   . PRO B 1 88  ? 132.402 139.244 163.977 1.00 82.32  ? 88   PRO B C   1 
ATOM   7551  O  O   . PRO B 1 88  ? 131.607 140.141 163.685 1.00 82.32  ? 88   PRO B O   1 
ATOM   7552  C  CB  . PRO B 1 88  ? 131.380 136.966 164.332 1.00 82.32  ? 88   PRO B CB  1 
ATOM   7553  C  CG  . PRO B 1 88  ? 130.247 136.595 165.227 1.00 82.32  ? 88   PRO B CG  1 
ATOM   7554  C  CD  . PRO B 1 88  ? 129.817 137.844 165.918 1.00 82.32  ? 88   PRO B CD  1 
ATOM   7555  N  N   . TRP B 1 89  ? 133.618 139.139 163.434 1.00 85.08  ? 89   TRP B N   1 
ATOM   7556  C  CA  . TRP B 1 89  ? 134.124 140.172 162.535 1.00 85.08  ? 89   TRP B CA  1 
ATOM   7557  C  C   . TRP B 1 89  ? 133.284 140.288 161.268 1.00 85.08  ? 89   TRP B C   1 
ATOM   7558  O  O   . TRP B 1 89  ? 133.054 141.400 160.780 1.00 85.08  ? 89   TRP B O   1 
ATOM   7559  C  CB  . TRP B 1 89  ? 135.589 139.897 162.189 1.00 85.08  ? 89   TRP B CB  1 
ATOM   7560  C  CG  . TRP B 1 89  ? 135.807 138.681 161.341 1.00 85.08  ? 89   TRP B CG  1 
ATOM   7561  C  CD1 . TRP B 1 89  ? 136.047 137.411 161.778 1.00 85.08  ? 89   TRP B CD1 1 
ATOM   7562  C  CD2 . TRP B 1 89  ? 135.825 138.623 159.910 1.00 85.08  ? 89   TRP B CD2 1 
ATOM   7563  N  NE1 . TRP B 1 89  ? 136.203 136.564 160.708 1.00 85.08  ? 89   TRP B NE1 1 
ATOM   7564  C  CE2 . TRP B 1 89  ? 136.072 137.283 159.549 1.00 85.08  ? 89   TRP B CE2 1 
ATOM   7565  C  CE3 . TRP B 1 89  ? 135.651 139.572 158.898 1.00 85.08  ? 89   TRP B CE3 1 
ATOM   7566  C  CZ2 . TRP B 1 89  ? 136.150 136.870 158.221 1.00 85.08  ? 89   TRP B CZ2 1 
ATOM   7567  C  CZ3 . TRP B 1 89  ? 135.729 139.159 157.581 1.00 85.08  ? 89   TRP B CZ3 1 
ATOM   7568  C  CH2 . TRP B 1 89  ? 135.976 137.820 157.254 1.00 85.08  ? 89   TRP B CH2 1 
ATOM   7569  N  N   . TRP B 1 90  ? 132.822 139.161 160.718 1.00 83.56  ? 90   TRP B N   1 
ATOM   7570  C  CA  . TRP B 1 90  ? 131.989 139.230 159.522 1.00 83.56  ? 90   TRP B CA  1 
ATOM   7571  C  C   . TRP B 1 90  ? 130.643 139.881 159.816 1.00 83.56  ? 90   TRP B C   1 
ATOM   7572  O  O   . TRP B 1 90  ? 130.114 140.611 158.969 1.00 83.56  ? 90   TRP B O   1 
ATOM   7573  C  CB  . TRP B 1 90  ? 131.802 137.835 158.921 1.00 83.56  ? 90   TRP B CB  1 
ATOM   7574  C  CG  . TRP B 1 90  ? 131.027 136.879 159.775 1.00 83.56  ? 90   TRP B CG  1 
ATOM   7575  C  CD1 . TRP B 1 90  ? 129.670 136.768 159.858 1.00 83.56  ? 90   TRP B CD1 1 
ATOM   7576  C  CD2 . TRP B 1 90  ? 131.566 135.885 160.655 1.00 83.56  ? 90   TRP B CD2 1 
ATOM   7577  N  NE1 . TRP B 1 90  ? 129.330 135.772 160.741 1.00 83.56  ? 90   TRP B NE1 1 
ATOM   7578  C  CE2 . TRP B 1 90  ? 130.476 135.215 161.244 1.00 83.56  ? 90   TRP B CE2 1 
ATOM   7579  C  CE3 . TRP B 1 90  ? 132.863 135.500 161.005 1.00 83.56  ? 90   TRP B CE3 1 
ATOM   7580  C  CZ2 . TRP B 1 90  ? 130.643 134.181 162.163 1.00 83.56  ? 90   TRP B CZ2 1 
ATOM   7581  C  CZ3 . TRP B 1 90  ? 133.027 134.474 161.917 1.00 83.56  ? 90   TRP B CZ3 1 
ATOM   7582  C  CH2 . TRP B 1 90  ? 131.924 133.827 162.486 1.00 83.56  ? 90   TRP B CH2 1 
ATOM   7583  N  N   . VAL B 1 91  ? 130.083 139.646 161.004 1.00 80.62  ? 91   VAL B N   1 
ATOM   7584  C  CA  . VAL B 1 91  ? 128.852 140.329 161.391 1.00 80.62  ? 91   VAL B CA  1 
ATOM   7585  C  C   . VAL B 1 91  ? 129.083 141.832 161.482 1.00 80.62  ? 91   VAL B C   1 
ATOM   7586  O  O   . VAL B 1 91  ? 128.239 142.630 161.057 1.00 80.62  ? 91   VAL B O   1 
ATOM   7587  C  CB  . VAL B 1 91  ? 128.315 139.761 162.717 1.00 80.62  ? 91   VAL B CB  1 
ATOM   7588  C  CG1 . VAL B 1 91  ? 126.972 140.389 163.056 1.00 80.62  ? 91   VAL B CG1 1 
ATOM   7589  C  CG2 . VAL B 1 91  ? 128.191 138.251 162.634 1.00 80.62  ? 91   VAL B CG2 1 
ATOM   7590  N  N   . HIS B 1 92  ? 130.220 142.241 162.049 1.00 76.87  ? 92   HIS B N   1 
ATOM   7591  C  CA  . HIS B 1 92  ? 130.537 143.663 162.134 1.00 76.87  ? 92   HIS B CA  1 
ATOM   7592  C  C   . HIS B 1 92  ? 130.687 144.276 160.747 1.00 76.87  ? 92   HIS B C   1 
ATOM   7593  O  O   . HIS B 1 92  ? 130.193 145.381 160.491 1.00 76.87  ? 92   HIS B O   1 
ATOM   7594  C  CB  . HIS B 1 92  ? 131.810 143.865 162.954 1.00 76.87  ? 92   HIS B CB  1 
ATOM   7595  C  CG  . HIS B 1 92  ? 132.112 145.298 163.256 1.00 76.87  ? 92   HIS B CG  1 
ATOM   7596  N  ND1 . HIS B 1 92  ? 131.126 146.242 163.448 1.00 76.87  ? 92   HIS B ND1 1 
ATOM   7597  C  CD2 . HIS B 1 92  ? 133.290 145.950 163.402 1.00 76.87  ? 92   HIS B CD2 1 
ATOM   7598  C  CE1 . HIS B 1 92  ? 131.683 147.413 163.698 1.00 76.87  ? 92   HIS B CE1 1 
ATOM   7599  N  NE2 . HIS B 1 92  ? 132.995 147.263 163.676 1.00 76.87  ? 92   HIS B NE2 1 
ATOM   7600  N  N   . LEU B 1 93  ? 131.359 143.569 159.837 1.00 77.49  ? 93   LEU B N   1 
ATOM   7601  C  CA  . LEU B 1 93  ? 131.495 144.064 158.471 1.00 77.49  ? 93   LEU B CA  1 
ATOM   7602  C  C   . LEU B 1 93  ? 130.137 144.192 157.793 1.00 77.49  ? 93   LEU B C   1 
ATOM   7603  O  O   . LEU B 1 93  ? 129.867 145.187 157.107 1.00 77.49  ? 93   LEU B O   1 
ATOM   7604  C  CB  . LEU B 1 93  ? 132.410 143.138 157.670 1.00 77.49  ? 93   LEU B CB  1 
ATOM   7605  C  CG  . LEU B 1 93  ? 132.681 143.524 156.215 1.00 77.49  ? 93   LEU B CG  1 
ATOM   7606  C  CD1 . LEU B 1 93  ? 133.311 144.902 156.126 1.00 77.49  ? 93   LEU B CD1 1 
ATOM   7607  C  CD2 . LEU B 1 93  ? 133.565 142.482 155.548 1.00 77.49  ? 93   LEU B CD2 1 
ATOM   7608  N  N   . TRP B 1 94  ? 129.266 143.197 157.976 1.00 81.67  ? 94   TRP B N   1 
ATOM   7609  C  CA  . TRP B 1 94  ? 127.941 143.253 157.369 1.00 81.67  ? 94   TRP B CA  1 
ATOM   7610  C  C   . TRP B 1 94  ? 127.124 144.414 157.921 1.00 81.67  ? 94   TRP B C   1 
ATOM   7611  O  O   . TRP B 1 94  ? 126.464 145.133 157.162 1.00 81.67  ? 94   TRP B O   1 
ATOM   7612  C  CB  . TRP B 1 94  ? 127.205 141.932 157.584 1.00 81.67  ? 94   TRP B CB  1 
ATOM   7613  C  CG  . TRP B 1 94  ? 125.762 141.986 157.188 1.00 81.67  ? 94   TRP B CG  1 
ATOM   7614  C  CD1 . TRP B 1 94  ? 124.682 141.839 158.008 1.00 81.67  ? 94   TRP B CD1 1 
ATOM   7615  C  CD2 . TRP B 1 94  ? 125.240 142.213 155.873 1.00 81.67  ? 94   TRP B CD2 1 
ATOM   7616  N  NE1 . TRP B 1 94  ? 123.520 141.955 157.284 1.00 81.67  ? 94   TRP B NE1 1 
ATOM   7617  C  CE2 . TRP B 1 94  ? 123.836 142.185 155.971 1.00 81.67  ? 94   TRP B CE2 1 
ATOM   7618  C  CE3 . TRP B 1 94  ? 125.825 142.434 154.622 1.00 81.67  ? 94   TRP B CE3 1 
ATOM   7619  C  CZ2 . TRP B 1 94  ? 123.007 142.371 154.867 1.00 81.67  ? 94   TRP B CZ2 1 
ATOM   7620  C  CZ3 . TRP B 1 94  ? 125.000 142.618 153.528 1.00 81.67  ? 94   TRP B CZ3 1 
ATOM   7621  C  CH2 . TRP B 1 94  ? 123.607 142.585 153.657 1.00 81.67  ? 94   TRP B CH2 1 
ATOM   7622  N  N   . VAL B 1 95  ? 127.154 144.616 159.241 1.00 76.75  ? 95   VAL B N   1 
ATOM   7623  C  CA  . VAL B 1 95  ? 126.369 145.699 159.826 1.00 76.75  ? 95   VAL B CA  1 
ATOM   7624  C  C   . VAL B 1 95  ? 126.944 147.055 159.431 1.00 76.75  ? 95   VAL B C   1 
ATOM   7625  O  O   . VAL B 1 95  ? 126.206 148.043 159.334 1.00 76.75  ? 95   VAL B O   1 
ATOM   7626  C  CB  . VAL B 1 95  ? 126.263 145.536 161.356 1.00 76.75  ? 95   VAL B CB  1 
ATOM   7627  C  CG1 . VAL B 1 95  ? 127.553 145.937 162.049 1.00 76.75  ? 95   VAL B CG1 1 
ATOM   7628  C  CG2 . VAL B 1 95  ? 125.088 146.339 161.896 1.00 76.75  ? 95   VAL B CG2 1 
ATOM   7629  N  N   . CYS B 1 96  ? 128.257 147.134 159.197 1.00 77.11  ? 96   CYS B N   1 
ATOM   7630  C  CA  . CYS B 1 96  ? 128.828 148.360 158.651 1.00 77.11  ? 96   CYS B CA  1 
ATOM   7631  C  C   . CYS B 1 96  ? 128.350 148.600 157.225 1.00 77.11  ? 96   CYS B C   1 
ATOM   7632  O  O   . CYS B 1 96  ? 128.036 149.735 156.850 1.00 77.11  ? 96   CYS B O   1 
ATOM   7633  C  CB  . CYS B 1 96  ? 130.355 148.300 158.703 1.00 77.11  ? 96   CYS B CB  1 
ATOM   7634  S  SG  . CYS B 1 96  ? 131.061 148.562 160.345 1.00 77.11  ? 96   CYS B SG  1 
ATOM   7635  N  N   . TYR B 1 97  ? 128.287 147.540 156.416 1.00 81.89  ? 97   TYR B N   1 
ATOM   7636  C  CA  . TYR B 1 97  ? 127.873 147.680 155.024 1.00 81.89  ? 97   TYR B CA  1 
ATOM   7637  C  C   . TYR B 1 97  ? 126.366 147.854 154.878 1.00 81.89  ? 97   TYR B C   1 
ATOM   7638  O  O   . TYR B 1 97  ? 125.911 148.468 153.907 1.00 81.89  ? 97   TYR B O   1 
ATOM   7639  C  CB  . TYR B 1 97  ? 128.340 146.468 154.217 1.00 81.89  ? 97   TYR B CB  1 
ATOM   7640  C  CG  . TYR B 1 97  ? 128.166 146.616 152.722 1.00 81.89  ? 97   TYR B CG  1 
ATOM   7641  C  CD1 . TYR B 1 97  ? 129.114 147.282 151.957 1.00 81.89  ? 97   TYR B CD1 1 
ATOM   7642  C  CD2 . TYR B 1 97  ? 127.056 146.087 152.076 1.00 81.89  ? 97   TYR B CD2 1 
ATOM   7643  C  CE1 . TYR B 1 97  ? 128.960 147.419 150.590 1.00 81.89  ? 97   TYR B CE1 1 
ATOM   7644  C  CE2 . TYR B 1 97  ? 126.894 146.220 150.710 1.00 81.89  ? 97   TYR B CE2 1 
ATOM   7645  C  CZ  . TYR B 1 97  ? 127.848 146.886 149.972 1.00 81.89  ? 97   TYR B CZ  1 
ATOM   7646  O  OH  . TYR B 1 97  ? 127.691 147.020 148.612 1.00 81.89  ? 97   TYR B OH  1 
ATOM   7647  N  N   . ARG B 1 98  ? 125.581 147.334 155.820 1.00 83.73  ? 98   ARG B N   1 
ATOM   7648  C  CA  . ARG B 1 98  ? 124.126 147.329 155.708 1.00 83.73  ? 98   ARG B CA  1 
ATOM   7649  C  C   . ARG B 1 98  ? 123.499 148.689 156.017 1.00 83.73  ? 98   ARG B C   1 
ATOM   7650  O  O   . ARG B 1 98  ? 122.269 148.787 156.089 1.00 83.73  ? 98   ARG B O   1 
ATOM   7651  C  CB  . ARG B 1 98  ? 123.538 146.256 156.633 1.00 83.73  ? 98   ARG B CB  1 
ATOM   7652  C  CG  . ARG B 1 98  ? 122.134 145.789 156.263 1.00 83.73  ? 98   ARG B CG  1 
ATOM   7653  C  CD  . ARG B 1 98  ? 121.626 144.723 157.219 1.00 83.73  ? 98   ARG B CD  1 
ATOM   7654  N  NE  . ARG B 1 98  ? 121.409 145.251 158.560 1.00 83.73  ? 98   ARG B NE  1 
ATOM   7655  C  CZ  . ARG B 1 98  ? 121.113 144.509 159.618 1.00 83.73  ? 98   ARG B CZ  1 
ATOM   7656  N  NH1 . ARG B 1 98  ? 120.992 143.195 159.529 1.00 83.73  ? 98   ARG B NH1 1 
ATOM   7657  N  NH2 . ARG B 1 98  ? 120.931 145.101 160.795 1.00 83.73  ? 98   ARG B NH2 1 
ATOM   7658  N  N   . ASN B 1 99  ? 124.302 149.735 156.195 1.00 80.03  ? 99   ASN B N   1 
ATOM   7659  C  CA  . ASN B 1 99  ? 123.748 151.041 156.511 1.00 80.03  ? 99   ASN B CA  1 
ATOM   7660  C  C   . ASN B 1 99  ? 122.922 151.575 155.340 1.00 80.03  ? 99   ASN B C   1 
ATOM   7661  O  O   . ASN B 1 99  ? 123.170 151.227 154.182 1.00 80.03  ? 99   ASN B O   1 
ATOM   7662  C  CB  . ASN B 1 99  ? 124.860 152.022 156.883 1.00 80.03  ? 99   ASN B CB  1 
ATOM   7663  C  CG  . ASN B 1 99  ? 125.905 152.177 155.795 1.00 80.03  ? 99   ASN B CG  1 
ATOM   7664  O  OD1 . ASN B 1 99  ? 125.781 151.618 154.709 1.00 80.03  ? 99   ASN B OD1 1 
ATOM   7665  N  ND2 . ASN B 1 99  ? 126.947 152.946 156.088 1.00 80.03  ? 99   ASN B ND2 1 
ATOM   7666  N  N   . PRO B 1 100 ? 121.907 152.398 155.620 1.00 80.81  ? 100  PRO B N   1 
ATOM   7667  C  CA  . PRO B 1 100 ? 121.036 152.881 154.536 1.00 80.81  ? 100  PRO B CA  1 
ATOM   7668  C  C   . PRO B 1 100 ? 121.762 153.679 153.470 1.00 80.81  ? 100  PRO B C   1 
ATOM   7669  O  O   . PRO B 1 100 ? 121.380 153.609 152.296 1.00 80.81  ? 100  PRO B O   1 
ATOM   7670  C  CB  . PRO B 1 100 ? 120.006 153.745 155.279 1.00 80.81  ? 100  PRO B CB  1 
ATOM   7671  C  CG  . PRO B 1 100 ? 120.017 153.227 156.679 1.00 80.81  ? 100  PRO B CG  1 
ATOM   7672  C  CD  . PRO B 1 100 ? 121.441 152.849 156.942 1.00 80.81  ? 100  PRO B CD  1 
ATOM   7673  N  N   . PHE B 1 101 ? 122.797 154.436 153.838 1.00 80.60  ? 101  PHE B N   1 
ATOM   7674  C  CA  . PHE B 1 101 ? 123.433 155.337 152.881 1.00 80.60  ? 101  PHE B CA  1 
ATOM   7675  C  C   . PHE B 1 101 ? 124.141 154.569 151.771 1.00 80.60  ? 101  PHE B C   1 
ATOM   7676  O  O   . PHE B 1 101 ? 123.963 154.872 150.587 1.00 80.60  ? 101  PHE B O   1 
ATOM   7677  C  CB  . PHE B 1 101 ? 124.405 156.266 153.606 1.00 80.60  ? 101  PHE B CB  1 
ATOM   7678  C  CG  . PHE B 1 101 ? 123.765 157.066 154.699 1.00 80.60  ? 101  PHE B CG  1 
ATOM   7679  C  CD1 . PHE B 1 101 ? 122.785 157.999 154.405 1.00 80.60  ? 101  PHE B CD1 1 
ATOM   7680  C  CD2 . PHE B 1 101 ? 124.131 156.877 156.020 1.00 80.60  ? 101  PHE B CD2 1 
ATOM   7681  C  CE1 . PHE B 1 101 ? 122.188 158.734 155.408 1.00 80.60  ? 101  PHE B CE1 1 
ATOM   7682  C  CE2 . PHE B 1 101 ? 123.537 157.608 157.027 1.00 80.60  ? 101  PHE B CE2 1 
ATOM   7683  C  CZ  . PHE B 1 101 ? 122.565 158.539 156.721 1.00 80.60  ? 101  PHE B CZ  1 
ATOM   7684  N  N   . ASN B 1 102 ? 124.949 153.570 152.132 1.00 78.18  ? 102  ASN B N   1 
ATOM   7685  C  CA  . ASN B 1 102 ? 125.682 152.820 151.115 1.00 78.18  ? 102  ASN B CA  1 
ATOM   7686  C  C   . ASN B 1 102 ? 124.740 152.002 150.240 1.00 78.18  ? 102  ASN B C   1 
ATOM   7687  O  O   . ASN B 1 102 ? 124.928 151.920 149.020 1.00 78.18  ? 102  ASN B O   1 
ATOM   7688  C  CB  . ASN B 1 102 ? 126.721 151.917 151.776 1.00 78.18  ? 102  ASN B CB  1 
ATOM   7689  C  CG  . ASN B 1 102 ? 127.869 152.699 152.381 1.00 78.18  ? 102  ASN B CG  1 
ATOM   7690  O  OD1 . ASN B 1 102 ? 128.271 152.453 153.518 1.00 78.18  ? 102  ASN B OD1 1 
ATOM   7691  N  ND2 . ASN B 1 102 ? 128.394 153.658 151.628 1.00 78.18  ? 102  ASN B ND2 1 
ATOM   7692  N  N   . ILE B 1 103 ? 123.723 151.386 150.847 1.00 77.35  ? 103  ILE B N   1 
ATOM   7693  C  CA  . ILE B 1 103 ? 122.756 150.608 150.078 1.00 77.35  ? 103  ILE B CA  1 
ATOM   7694  C  C   . ILE B 1 103 ? 122.009 151.507 149.102 1.00 77.35  ? 103  ILE B C   1 
ATOM   7695  O  O   . ILE B 1 103 ? 121.816 151.155 147.931 1.00 77.35  ? 103  ILE B O   1 
ATOM   7696  C  CB  . ILE B 1 103 ? 121.791 149.872 151.027 1.00 77.35  ? 103  ILE B CB  1 
ATOM   7697  C  CG1 . ILE B 1 103 ? 122.474 148.644 151.630 1.00 77.35  ? 103  ILE B CG1 1 
ATOM   7698  C  CG2 . ILE B 1 103 ? 120.516 149.473 150.300 1.00 77.35  ? 103  ILE B CG2 1 
ATOM   7699  C  CD1 . ILE B 1 103 ? 121.600 147.870 152.592 1.00 77.35  ? 103  ILE B CD1 1 
ATOM   7700  N  N   . LEU B 1 104 ? 121.582 152.682 149.568 1.00 73.68  ? 104  LEU B N   1 
ATOM   7701  C  CA  . LEU B 1 104 ? 120.888 153.618 148.692 1.00 73.68  ? 104  LEU B CA  1 
ATOM   7702  C  C   . LEU B 1 104 ? 121.806 154.126 147.588 1.00 73.68  ? 104  LEU B C   1 
ATOM   7703  O  O   . LEU B 1 104 ? 121.367 154.304 146.448 1.00 73.68  ? 104  LEU B O   1 
ATOM   7704  C  CB  . LEU B 1 104 ? 120.328 154.781 149.510 1.00 73.68  ? 104  LEU B CB  1 
ATOM   7705  C  CG  . LEU B 1 104 ? 119.107 155.488 148.919 1.00 73.68  ? 104  LEU B CG  1 
ATOM   7706  C  CD1 . LEU B 1 104 ? 117.961 154.508 148.732 1.00 73.68  ? 104  LEU B CD1 1 
ATOM   7707  C  CD2 . LEU B 1 104 ? 118.685 156.652 149.801 1.00 73.68  ? 104  LEU B CD2 1 
ATOM   7708  N  N   . LEU B 1 105 ? 123.081 154.362 147.905 1.00 74.09  ? 105  LEU B N   1 
ATOM   7709  C  CA  . LEU B 1 105 ? 124.037 154.775 146.882 1.00 74.09  ? 105  LEU B CA  1 
ATOM   7710  C  C   . LEU B 1 105 ? 124.180 153.710 145.804 1.00 74.09  ? 105  LEU B C   1 
ATOM   7711  O  O   . LEU B 1 105 ? 124.174 154.016 144.608 1.00 74.09  ? 105  LEU B O   1 
ATOM   7712  C  CB  . LEU B 1 105 ? 125.396 155.071 147.517 1.00 74.09  ? 105  LEU B CB  1 
ATOM   7713  C  CG  . LEU B 1 105 ? 125.714 156.513 147.911 1.00 74.09  ? 105  LEU B CG  1 
ATOM   7714  C  CD1 . LEU B 1 105 ? 127.181 156.632 148.277 1.00 74.09  ? 105  LEU B CD1 1 
ATOM   7715  C  CD2 . LEU B 1 105 ? 125.364 157.467 146.783 1.00 74.09  ? 105  LEU B CD2 1 
ATOM   7716  N  N   . THR B 1 106 ? 124.311 152.446 146.213 1.00 78.78  ? 106  THR B N   1 
ATOM   7717  C  CA  . THR B 1 106 ? 124.448 151.368 145.239 1.00 78.78  ? 106  THR B CA  1 
ATOM   7718  C  C   . THR B 1 106 ? 123.188 151.222 144.393 1.00 78.78  ? 106  THR B C   1 
ATOM   7719  O  O   . THR B 1 106 ? 123.266 151.039 143.170 1.00 78.78  ? 106  THR B O   1 
ATOM   7720  C  CB  . THR B 1 106 ? 124.773 150.056 145.953 1.00 78.78  ? 106  THR B CB  1 
ATOM   7721  O  OG1 . THR B 1 106 ? 126.004 150.196 146.673 1.00 78.78  ? 106  THR B OG1 1 
ATOM   7722  C  CG2 . THR B 1 106 ? 124.909 148.922 144.950 1.00 78.78  ? 106  THR B CG2 1 
ATOM   7723  N  N   . ILE B 1 107 ? 122.016 151.307 145.025 1.00 77.40  ? 107  ILE B N   1 
ATOM   7724  C  CA  . ILE B 1 107 ? 120.760 151.168 144.292 1.00 77.40  ? 107  ILE B CA  1 
ATOM   7725  C  C   . ILE B 1 107 ? 120.598 152.309 143.294 1.00 77.40  ? 107  ILE B C   1 
ATOM   7726  O  O   . ILE B 1 107 ? 120.210 152.094 142.138 1.00 77.40  ? 107  ILE B O   1 
ATOM   7727  C  CB  . ILE B 1 107 ? 119.576 151.096 145.273 1.00 77.40  ? 107  ILE B CB  1 
ATOM   7728  C  CG1 . ILE B 1 107 ? 119.498 149.707 145.909 1.00 77.40  ? 107  ILE B CG1 1 
ATOM   7729  C  CG2 . ILE B 1 107 ? 118.271 151.432 144.568 1.00 77.40  ? 107  ILE B CG2 1 
ATOM   7730  C  CD1 . ILE B 1 107 ? 118.350 149.542 146.879 1.00 77.40  ? 107  ILE B CD1 1 
ATOM   7731  N  N   . LEU B 1 108 ? 120.897 153.538 143.722 1.00 80.31  ? 108  LEU B N   1 
ATOM   7732  C  CA  . LEU B 1 108 ? 120.813 154.680 142.820 1.00 80.31  ? 108  LEU B CA  1 
ATOM   7733  C  C   . LEU B 1 108 ? 121.827 154.578 141.691 1.00 80.31  ? 108  LEU B C   1 
ATOM   7734  O  O   . LEU B 1 108 ? 121.524 154.963 140.560 1.00 80.31  ? 108  LEU B O   1 
ATOM   7735  C  CB  . LEU B 1 108 ? 121.009 155.981 143.596 1.00 80.31  ? 108  LEU B CB  1 
ATOM   7736  C  CG  . LEU B 1 108 ? 119.841 156.414 144.483 1.00 80.31  ? 108  LEU B CG  1 
ATOM   7737  C  CD1 . LEU B 1 108 ? 120.090 157.798 145.058 1.00 80.31  ? 108  LEU B CD1 1 
ATOM   7738  C  CD2 . LEU B 1 108 ? 118.534 156.381 143.709 1.00 80.31  ? 108  LEU B CD2 1 
ATOM   7739  N  N   . GLY B 1 109 ? 123.030 154.073 141.974 1.00 83.73  ? 109  GLY B N   1 
ATOM   7740  C  CA  . GLY B 1 109 ? 123.994 153.859 140.909 1.00 83.73  ? 109  GLY B CA  1 
ATOM   7741  C  C   . GLY B 1 109 ? 123.497 152.872 139.875 1.00 83.73  ? 109  GLY B C   1 
ATOM   7742  O  O   . GLY B 1 109 ? 123.587 153.121 138.669 1.00 83.73  ? 109  GLY B O   1 
ATOM   7743  N  N   . ALA B 1 110 ? 122.951 151.743 140.334 1.00 85.61  ? 110  ALA B N   1 
ATOM   7744  C  CA  . ALA B 1 110 ? 122.412 150.756 139.405 1.00 85.61  ? 110  ALA B CA  1 
ATOM   7745  C  C   . ALA B 1 110 ? 121.272 151.341 138.582 1.00 85.61  ? 110  ALA B C   1 
ATOM   7746  O  O   . ALA B 1 110 ? 121.208 151.137 137.364 1.00 85.61  ? 110  ALA B O   1 
ATOM   7747  C  CB  . ALA B 1 110 ? 121.945 149.517 140.167 1.00 85.61  ? 110  ALA B CB  1 
ATOM   7748  N  N   . ILE B 1 111 ? 120.374 152.089 139.225 1.00 84.72  ? 111  ILE B N   1 
ATOM   7749  C  CA  . ILE B 1 111 ? 119.243 152.671 138.510 1.00 84.72  ? 111  ILE B CA  1 
ATOM   7750  C  C   . ILE B 1 111 ? 119.718 153.695 137.484 1.00 84.72  ? 111  ILE B C   1 
ATOM   7751  O  O   . ILE B 1 111 ? 119.252 153.708 136.338 1.00 84.72  ? 111  ILE B O   1 
ATOM   7752  C  CB  . ILE B 1 111 ? 118.246 153.289 139.507 1.00 84.72  ? 111  ILE B CB  1 
ATOM   7753  C  CG1 . ILE B 1 111 ? 117.499 152.190 140.264 1.00 84.72  ? 111  ILE B CG1 1 
ATOM   7754  C  CG2 . ILE B 1 111 ? 117.260 154.192 138.789 1.00 84.72  ? 111  ILE B CG2 1 
ATOM   7755  C  CD1 . ILE B 1 111 ? 116.567 152.715 141.333 1.00 84.72  ? 111  ILE B CD1 1 
ATOM   7756  N  N   . SER B 1 112 ? 120.657 154.561 137.871 1.00 88.51  ? 112  SER B N   1 
ATOM   7757  C  CA  . SER B 1 112 ? 121.071 155.654 136.999 1.00 88.51  ? 112  SER B CA  1 
ATOM   7758  C  C   . SER B 1 112 ? 121.912 155.158 135.831 1.00 88.51  ? 112  SER B C   1 
ATOM   7759  O  O   . SER B 1 112 ? 121.792 155.673 134.714 1.00 88.51  ? 112  SER B O   1 
ATOM   7760  C  CB  . SER B 1 112 ? 121.839 156.701 137.805 1.00 88.51  ? 112  SER B CB  1 
ATOM   7761  O  OG  . SER B 1 112 ? 120.961 157.455 138.622 1.00 88.51  ? 112  SER B OG  1 
ATOM   7762  N  N   . TYR B 1 113 ? 122.772 154.164 136.061 1.00 92.42  ? 113  TYR B N   1 
ATOM   7763  C  CA  . TYR B 1 113 ? 123.675 153.676 135.027 1.00 92.42  ? 113  TYR B CA  1 
ATOM   7764  C  C   . TYR B 1 113 ? 123.304 152.279 134.541 1.00 92.42  ? 113  TYR B C   1 
ATOM   7765  O  O   . TYR B 1 113 ? 124.161 151.551 134.030 1.00 92.42  ? 113  TYR B O   1 
ATOM   7766  C  CB  . TYR B 1 113 ? 125.116 153.711 135.532 1.00 92.42  ? 113  TYR B CB  1 
ATOM   7767  C  CG  . TYR B 1 113 ? 125.590 155.103 135.887 1.00 92.42  ? 113  TYR B CG  1 
ATOM   7768  C  CD1 . TYR B 1 113 ? 125.722 156.081 134.910 1.00 92.42  ? 113  TYR B CD1 1 
ATOM   7769  C  CD2 . TYR B 1 113 ? 125.896 155.443 137.198 1.00 92.42  ? 113  TYR B CD2 1 
ATOM   7770  C  CE1 . TYR B 1 113 ? 126.151 157.355 135.227 1.00 92.42  ? 113  TYR B CE1 1 
ATOM   7771  C  CE2 . TYR B 1 113 ? 126.325 156.715 137.525 1.00 92.42  ? 113  TYR B CE2 1 
ATOM   7772  C  CZ  . TYR B 1 113 ? 126.451 157.667 136.535 1.00 92.42  ? 113  TYR B CZ  1 
ATOM   7773  O  OH  . TYR B 1 113 ? 126.878 158.936 136.854 1.00 92.42  ? 113  TYR B OH  1 
ATOM   7774  N  N   . ALA B 1 114 ? 122.037 151.890 134.691 1.00 96.64  ? 114  ALA B N   1 
ATOM   7775  C  CA  . ALA B 1 114 ? 121.562 150.643 134.109 1.00 96.64  ? 114  ALA B CA  1 
ATOM   7776  C  C   . ALA B 1 114 ? 121.237 150.777 132.629 1.00 96.64  ? 114  ALA B C   1 
ATOM   7777  O  O   . ALA B 1 114 ? 120.944 149.768 131.978 1.00 96.64  ? 114  ALA B O   1 
ATOM   7778  C  CB  . ALA B 1 114 ? 120.329 150.144 134.864 1.00 96.64  ? 114  ALA B CB  1 
ATOM   7779  N  N   . THR B 1 115 ? 121.280 151.993 132.085 1.00 107.84 ? 115  THR B N   1 
ATOM   7780  C  CA  . THR B 1 115 ? 121.026 152.208 130.666 1.00 107.84 ? 115  THR B CA  1 
ATOM   7781  C  C   . THR B 1 115 ? 122.260 151.853 129.847 1.00 107.84 ? 115  THR B C   1 
ATOM   7782  O  O   . THR B 1 115 ? 122.828 152.714 129.167 1.00 107.84 ? 115  THR B O   1 
ATOM   7783  C  CB  . THR B 1 115 ? 120.617 153.659 130.401 1.00 107.84 ? 115  THR B CB  1 
ATOM   7784  O  OG1 . THR B 1 115 ? 121.760 154.512 130.541 1.00 107.84 ? 115  THR B OG1 1 
ATOM   7785  C  CG2 . THR B 1 115 ? 119.541 154.097 131.382 1.00 107.84 ? 115  THR B CG2 1 
ATOM   7786  N  N   . GLU B 1 116 ? 122.687 150.593 129.923 1.00 109.88 ? 116  GLU B N   1 
ATOM   7787  C  CA  . GLU B 1 116 ? 123.853 150.062 129.223 1.00 109.88 ? 116  GLU B CA  1 
ATOM   7788  C  C   . GLU B 1 116 ? 125.155 150.742 129.634 1.00 109.88 ? 116  GLU B C   1 
ATOM   7789  O  O   . GLU B 1 116 ? 126.196 150.502 129.012 1.00 109.88 ? 116  GLU B O   1 
ATOM   7790  C  CB  . GLU B 1 116 ? 123.682 150.147 127.700 1.00 109.88 ? 116  GLU B CB  1 
ATOM   7791  C  CG  . GLU B 1 116 ? 122.563 149.279 127.149 1.00 109.88 ? 116  GLU B CG  1 
ATOM   7792  C  CD  . GLU B 1 116 ? 122.412 149.408 125.646 1.00 109.88 ? 116  GLU B CD  1 
ATOM   7793  O  OE1 . GLU B 1 116 ? 123.109 150.255 125.048 1.00 109.88 ? 116  GLU B OE1 1 
ATOM   7794  O  OE2 . GLU B 1 116 ? 121.598 148.662 125.063 1.00 109.88 ? 116  GLU B OE2 1 
ATOM   7795  N  N   . ASP B 1 117 ? 125.126 151.585 130.665 1.00 103.70 ? 117  ASP B N   1 
ATOM   7796  C  CA  . ASP B 1 117 ? 126.321 152.288 131.129 1.00 103.70 ? 117  ASP B CA  1 
ATOM   7797  C  C   . ASP B 1 117 ? 126.932 151.572 132.334 1.00 103.70 ? 117  ASP B C   1 
ATOM   7798  O  O   . ASP B 1 117 ? 126.992 152.093 133.447 1.00 103.70 ? 117  ASP B O   1 
ATOM   7799  C  CB  . ASP B 1 117 ? 125.987 153.738 131.457 1.00 103.70 ? 117  ASP B CB  1 
ATOM   7800  C  CG  . ASP B 1 117 ? 127.220 154.615 131.539 1.00 103.70 ? 117  ASP B CG  1 
ATOM   7801  O  OD1 . ASP B 1 117 ? 128.333 154.108 131.282 1.00 103.70 ? 117  ASP B OD1 1 
ATOM   7802  O  OD2 . ASP B 1 117 ? 127.077 155.812 131.863 1.00 103.70 ? 117  ASP B OD2 1 
ATOM   7803  N  N   . LEU B 1 118 ? 127.391 150.351 132.091 1.00 100.18 ? 118  LEU B N   1 
ATOM   7804  C  CA  . LEU B 1 118 ? 128.029 149.564 133.137 1.00 100.18 ? 118  LEU B CA  1 
ATOM   7805  C  C   . LEU B 1 118 ? 129.425 150.125 133.404 1.00 100.18 ? 118  LEU B C   1 
ATOM   7806  O  O   . LEU B 1 118 ? 129.895 151.047 132.732 1.00 100.18 ? 118  LEU B O   1 
ATOM   7807  C  CB  . LEU B 1 118 ? 128.057 148.089 132.750 1.00 100.18 ? 118  LEU B CB  1 
ATOM   7808  C  CG  . LEU B 1 118 ? 126.690 147.406 132.670 1.00 100.18 ? 118  LEU B CG  1 
ATOM   7809  C  CD1 . LEU B 1 118 ? 126.837 145.895 132.732 1.00 100.18 ? 118  LEU B CD1 1 
ATOM   7810  C  CD2 . LEU B 1 118 ? 125.774 147.904 133.780 1.00 100.18 ? 118  LEU B CD2 1 
ATOM   7811  N  N   . PHE B 1 119 ? 130.082 149.588 134.436 1.00 95.19  ? 119  PHE B N   1 
ATOM   7812  C  CA  . PHE B 1 119 ? 131.424 149.987 134.855 1.00 95.19  ? 119  PHE B CA  1 
ATOM   7813  C  C   . PHE B 1 119 ? 131.392 151.394 135.448 1.00 95.19  ? 119  PHE B C   1 
ATOM   7814  O  O   . PHE B 1 119 ? 132.405 151.895 135.943 1.00 95.19  ? 119  PHE B O   1 
ATOM   7815  C  CB  . PHE B 1 119 ? 132.410 149.880 133.681 1.00 95.19  ? 119  PHE B CB  1 
ATOM   7816  C  CG  . PHE B 1 119 ? 133.796 150.364 133.993 1.00 95.19  ? 119  PHE B CG  1 
ATOM   7817  C  CD1 . PHE B 1 119 ? 134.588 149.696 134.912 1.00 95.19  ? 119  PHE B CD1 1 
ATOM   7818  C  CD2 . PHE B 1 119 ? 134.309 151.484 133.363 1.00 95.19  ? 119  PHE B CD2 1 
ATOM   7819  C  CE1 . PHE B 1 119 ? 135.866 150.139 135.197 1.00 95.19  ? 119  PHE B CE1 1 
ATOM   7820  C  CE2 . PHE B 1 119 ? 135.585 151.931 133.644 1.00 95.19  ? 119  PHE B CE2 1 
ATOM   7821  C  CZ  . PHE B 1 119 ? 136.365 151.258 134.562 1.00 95.19  ? 119  PHE B CZ  1 
ATOM   7822  N  N   . ALA B 1 120 ? 130.219 152.030 135.427 1.00 94.24  ? 120  ALA B N   1 
ATOM   7823  C  CA  . ALA B 1 120 ? 130.032 153.272 136.169 1.00 94.24  ? 120  ALA B CA  1 
ATOM   7824  C  C   . ALA B 1 120 ? 129.471 152.983 137.555 1.00 94.24  ? 120  ALA B C   1 
ATOM   7825  O  O   . ALA B 1 120 ? 130.097 153.297 138.577 1.00 94.24  ? 120  ALA B O   1 
ATOM   7826  C  CB  . ALA B 1 120 ? 129.108 154.213 135.394 1.00 94.24  ? 120  ALA B CB  1 
ATOM   7827  N  N   . ALA B 1 121 ? 128.288 152.364 137.604 1.00 86.47  ? 121  ALA B N   1 
ATOM   7828  C  CA  . ALA B 1 121 ? 127.740 151.911 138.877 1.00 86.47  ? 121  ALA B CA  1 
ATOM   7829  C  C   . ALA B 1 121 ? 128.663 150.896 139.533 1.00 86.47  ? 121  ALA B C   1 
ATOM   7830  O  O   . ALA B 1 121 ? 128.737 150.818 140.763 1.00 86.47  ? 121  ALA B O   1 
ATOM   7831  C  CB  . ALA B 1 121 ? 126.349 151.315 138.669 1.00 86.47  ? 121  ALA B CB  1 
ATOM   7832  N  N   . GLY B 1 122 ? 129.379 150.112 138.725 1.00 84.06  ? 122  GLY B N   1 
ATOM   7833  C  CA  . GLY B 1 122 ? 130.343 149.180 139.284 1.00 84.06  ? 122  GLY B CA  1 
ATOM   7834  C  C   . GLY B 1 122 ? 131.448 149.882 140.049 1.00 84.06  ? 122  GLY B C   1 
ATOM   7835  O  O   . GLY B 1 122 ? 131.796 149.488 141.163 1.00 84.06  ? 122  GLY B O   1 
ATOM   7836  N  N   . VAL B 1 123 ? 132.008 150.944 139.465 1.00 85.42  ? 123  VAL B N   1 
ATOM   7837  C  CA  . VAL B 1 123 ? 133.058 151.696 140.148 1.00 85.42  ? 123  VAL B CA  1 
ATOM   7838  C  C   . VAL B 1 123 ? 132.490 152.429 141.359 1.00 85.42  ? 123  VAL B C   1 
ATOM   7839  O  O   . VAL B 1 123 ? 133.161 152.565 142.390 1.00 85.42  ? 123  VAL B O   1 
ATOM   7840  C  CB  . VAL B 1 123 ? 133.760 152.655 139.168 1.00 85.42  ? 123  VAL B CB  1 
ATOM   7841  C  CG1 . VAL B 1 123 ? 134.636 153.647 139.918 1.00 85.42  ? 123  VAL B CG1 1 
ATOM   7842  C  CG2 . VAL B 1 123 ? 134.603 151.867 138.182 1.00 85.42  ? 123  VAL B CG2 1 
ATOM   7843  N  N   . ILE B 1 124 ? 131.249 152.914 141.259 1.00 79.98  ? 124  ILE B N   1 
ATOM   7844  C  CA  . ILE B 1 124 ? 130.620 153.560 142.413 1.00 79.98  ? 124  ILE B CA  1 
ATOM   7845  C  C   . ILE B 1 124 ? 130.500 152.575 143.570 1.00 79.98  ? 124  ILE B C   1 
ATOM   7846  O  O   . ILE B 1 124 ? 130.845 152.886 144.718 1.00 79.98  ? 124  ILE B O   1 
ATOM   7847  C  CB  . ILE B 1 124 ? 129.248 154.143 142.027 1.00 79.98  ? 124  ILE B CB  1 
ATOM   7848  C  CG1 . ILE B 1 124 ? 129.421 155.396 141.169 1.00 79.98  ? 124  ILE B CG1 1 
ATOM   7849  C  CG2 . ILE B 1 124 ? 128.432 154.459 143.270 1.00 79.98  ? 124  ILE B CG2 1 
ATOM   7850  C  CD1 . ILE B 1 124 ? 128.118 155.949 140.639 1.00 79.98  ? 124  ILE B CD1 1 
ATOM   7851  N  N   . ALA B 1 125 ? 130.019 151.365 143.278 1.00 79.41  ? 125  ALA B N   1 
ATOM   7852  C  CA  . ALA B 1 125 ? 129.905 150.338 144.308 1.00 79.41  ? 125  ALA B CA  1 
ATOM   7853  C  C   . ALA B 1 125 ? 131.276 149.925 144.827 1.00 79.41  ? 125  ALA B C   1 
ATOM   7854  O  O   . ALA B 1 125 ? 131.426 149.601 146.008 1.00 79.41  ? 125  ALA B O   1 
ATOM   7855  C  CB  . ALA B 1 125 ? 129.150 149.127 143.762 1.00 79.41  ? 125  ALA B CB  1 
ATOM   7856  N  N   . LEU B 1 126 ? 132.286 149.924 143.956 1.00 79.63  ? 126  LEU B N   1 
ATOM   7857  C  CA  . LEU B 1 126 ? 133.644 149.617 144.393 1.00 79.63  ? 126  LEU B CA  1 
ATOM   7858  C  C   . LEU B 1 126 ? 134.147 150.656 145.387 1.00 79.63  ? 126  LEU B C   1 
ATOM   7859  O  O   . LEU B 1 126 ? 134.767 150.316 146.398 1.00 79.63  ? 126  LEU B O   1 
ATOM   7860  C  CB  . LEU B 1 126 ? 134.575 149.531 143.183 1.00 79.63  ? 126  LEU B CB  1 
ATOM   7861  C  CG  . LEU B 1 126 ? 136.030 149.155 143.466 1.00 79.63  ? 126  LEU B CG  1 
ATOM   7862  C  CD1 . LEU B 1 126 ? 136.120 147.762 144.071 1.00 79.63  ? 126  LEU B CD1 1 
ATOM   7863  C  CD2 . LEU B 1 126 ? 136.869 149.248 142.201 1.00 79.63  ? 126  LEU B CD2 1 
ATOM   7864  N  N   . MET B 1 127 ? 133.889 151.935 145.111 1.00 78.33  ? 127  MET B N   1 
ATOM   7865  C  CA  . MET B 1 127 ? 134.290 152.993 146.035 1.00 78.33  ? 127  MET B CA  1 
ATOM   7866  C  C   . MET B 1 127 ? 133.527 152.888 147.351 1.00 78.33  ? 127  MET B C   1 
ATOM   7867  O  O   . MET B 1 127 ? 134.092 153.098 148.433 1.00 78.33  ? 127  MET B O   1 
ATOM   7868  C  CB  . MET B 1 127 ? 134.074 154.362 145.390 1.00 78.33  ? 127  MET B CB  1 
ATOM   7869  C  CG  . MET B 1 127 ? 135.168 154.756 144.412 1.00 78.33  ? 127  MET B CG  1 
ATOM   7870  S  SD  . MET B 1 127 ? 136.590 155.514 145.219 1.00 78.33  ? 127  MET B SD  1 
ATOM   7871  C  CE  . MET B 1 127 ? 137.891 155.109 144.056 1.00 78.33  ? 127  MET B CE  1 
ATOM   7872  N  N   . VAL B 1 128 ? 132.235 152.570 147.273 1.00 76.24  ? 128  VAL B N   1 
ATOM   7873  C  CA  . VAL B 1 128 ? 131.405 152.360 148.454 1.00 76.24  ? 128  VAL B CA  1 
ATOM   7874  C  C   . VAL B 1 128 ? 132.004 151.245 149.301 1.00 76.24  ? 128  VAL B C   1 
ATOM   7875  O  O   . VAL B 1 128 ? 132.144 151.379 150.522 1.00 76.24  ? 128  VAL B O   1 
ATOM   7876  C  CB  . VAL B 1 128 ? 129.955 152.035 148.055 1.00 76.24  ? 128  VAL B CB  1 
ATOM   7877  C  CG1 . VAL B 1 128 ? 129.175 151.547 149.252 1.00 76.24  ? 128  VAL B CG1 1 
ATOM   7878  C  CG2 . VAL B 1 128 ? 129.285 153.260 147.461 1.00 76.24  ? 128  VAL B CG2 1 
ATOM   7879  N  N   . ALA B 1 129 ? 132.373 150.142 148.647 1.00 74.16  ? 129  ALA B N   1 
ATOM   7880  C  CA  . ALA B 1 129 ? 132.962 149.014 149.356 1.00 74.16  ? 129  ALA B CA  1 
ATOM   7881  C  C   . ALA B 1 129 ? 134.312 149.380 149.956 1.00 74.16  ? 129  ALA B C   1 
ATOM   7882  O  O   . ALA B 1 129 ? 134.640 148.951 151.064 1.00 74.16  ? 129  ALA B O   1 
ATOM   7883  C  CB  . ALA B 1 129 ? 133.100 147.819 148.414 1.00 74.16  ? 129  ALA B CB  1 
ATOM   7884  N  N   . ILE B 1 130 ? 135.117 150.161 149.236 1.00 73.38  ? 130  ILE B N   1 
ATOM   7885  C  CA  . ILE B 1 130 ? 136.418 150.550 149.768 1.00 73.38  ? 130  ILE B CA  1 
ATOM   7886  C  C   . ILE B 1 130 ? 136.247 151.393 151.025 1.00 73.38  ? 130  ILE B C   1 
ATOM   7887  O  O   . ILE B 1 130 ? 136.940 151.183 152.028 1.00 73.38  ? 130  ILE B O   1 
ATOM   7888  C  CB  . ILE B 1 130 ? 137.243 151.279 148.692 1.00 73.38  ? 130  ILE B CB  1 
ATOM   7889  C  CG1 . ILE B 1 130 ? 137.697 150.293 147.614 1.00 73.38  ? 130  ILE B CG1 1 
ATOM   7890  C  CG2 . ILE B 1 130 ? 138.451 151.953 149.314 1.00 73.38  ? 130  ILE B CG2 1 
ATOM   7891  C  CD1 . ILE B 1 130 ? 138.534 150.924 146.524 1.00 73.38  ? 130  ILE B CD1 1 
ATOM   7892  N  N   . SER B 1 131 ? 135.312 152.345 151.000 1.00 71.59  ? 131  SER B N   1 
ATOM   7893  C  CA  . SER B 1 131 ? 135.037 153.135 152.197 1.00 71.59  ? 131  SER B CA  1 
ATOM   7894  C  C   . SER B 1 131 ? 134.527 152.254 153.334 1.00 71.59  ? 131  SER B C   1 
ATOM   7895  O  O   . SER B 1 131 ? 134.917 152.435 154.497 1.00 71.59  ? 131  SER B O   1 
ATOM   7896  C  CB  . SER B 1 131 ? 134.029 154.239 151.879 1.00 71.59  ? 131  SER B CB  1 
ATOM   7897  O  OG  . SER B 1 131 ? 133.734 155.010 153.031 1.00 71.59  ? 131  SER B OG  1 
ATOM   7898  N  N   . THR B 1 132 ? 133.653 151.295 153.015 1.00 72.96  ? 132  THR B N   1 
ATOM   7899  C  CA  . THR B 1 132 ? 133.113 150.410 154.043 1.00 72.96  ? 132  THR B CA  1 
ATOM   7900  C  C   . THR B 1 132 ? 134.211 149.574 154.691 1.00 72.96  ? 132  THR B C   1 
ATOM   7901  O  O   . THR B 1 132 ? 134.256 149.445 155.918 1.00 72.96  ? 132  THR B O   1 
ATOM   7902  C  CB  . THR B 1 132 ? 132.034 149.507 153.445 1.00 72.96  ? 132  THR B CB  1 
ATOM   7903  O  OG1 . THR B 1 132 ? 130.936 150.308 152.989 1.00 72.96  ? 132  THR B OG1 1 
ATOM   7904  C  CG2 . THR B 1 132 ? 131.529 148.517 154.482 1.00 72.96  ? 132  THR B CG2 1 
ATOM   7905  N  N   . LEU B 1 133 ? 135.108 149.004 153.883 1.00 71.85  ? 133  LEU B N   1 
ATOM   7906  C  CA  . LEU B 1 133 ? 136.216 148.229 154.436 1.00 71.85  ? 133  LEU B CA  1 
ATOM   7907  C  C   . LEU B 1 133 ? 137.195 149.104 155.209 1.00 71.85  ? 133  LEU B C   1 
ATOM   7908  O  O   . LEU B 1 133 ? 137.755 148.663 156.214 1.00 71.85  ? 133  LEU B O   1 
ATOM   7909  C  CB  . LEU B 1 133 ? 136.939 147.443 153.339 1.00 71.85  ? 133  LEU B CB  1 
ATOM   7910  C  CG  . LEU B 1 133 ? 136.342 146.103 152.879 1.00 71.85  ? 133  LEU B CG  1 
ATOM   7911  C  CD1 . LEU B 1 133 ? 135.080 146.222 152.050 1.00 71.85  ? 133  LEU B CD1 1 
ATOM   7912  C  CD2 . LEU B 1 133 ? 137.400 145.315 152.113 1.00 71.85  ? 133  LEU B CD2 1 
ATOM   7913  N  N   . LEU B 1 134 ? 137.416 150.344 154.766 1.00 66.98  ? 134  LEU B N   1 
ATOM   7914  C  CA  . LEU B 1 134 ? 138.256 151.253 155.545 1.00 66.98  ? 134  LEU B CA  1 
ATOM   7915  C  C   . LEU B 1 134 ? 137.669 151.481 156.934 1.00 66.98  ? 134  LEU B C   1 
ATOM   7916  O  O   . LEU B 1 134 ? 138.361 151.333 157.955 1.00 66.98  ? 134  LEU B O   1 
ATOM   7917  C  CB  . LEU B 1 134 ? 138.414 152.583 154.806 1.00 66.98  ? 134  LEU B CB  1 
ATOM   7918  C  CG  . LEU B 1 134 ? 139.106 153.707 155.580 1.00 66.98  ? 134  LEU B CG  1 
ATOM   7919  C  CD1 . LEU B 1 134 ? 140.560 153.363 155.851 1.00 66.98  ? 134  LEU B CD1 1 
ATOM   7920  C  CD2 . LEU B 1 134 ? 138.992 155.031 154.836 1.00 66.98  ? 134  LEU B CD2 1 
ATOM   7921  N  N   . ASN B 1 135 ? 136.380 151.825 156.987 1.00 65.43  ? 135  ASN B N   1 
ATOM   7922  C  CA  . ASN B 1 135 ? 135.721 152.057 158.267 1.00 65.43  ? 135  ASN B CA  1 
ATOM   7923  C  C   . ASN B 1 135 ? 135.744 150.799 159.127 1.00 65.43  ? 135  ASN B C   1 
ATOM   7924  O  O   . ASN B 1 135 ? 136.010 150.860 160.334 1.00 65.43  ? 135  ASN B O   1 
ATOM   7925  C  CB  . ASN B 1 135 ? 134.283 152.524 158.035 1.00 65.43  ? 135  ASN B CB  1 
ATOM   7926  C  CG  . ASN B 1 135 ? 134.193 154.009 157.745 1.00 65.43  ? 135  ASN B CG  1 
ATOM   7927  O  OD1 . ASN B 1 135 ? 135.189 154.650 157.415 1.00 65.43  ? 135  ASN B OD1 1 
ATOM   7928  N  ND2 . ASN B 1 135 ? 132.993 154.564 157.870 1.00 65.43  ? 135  ASN B ND2 1 
ATOM   7929  N  N   . PHE B 1 136 ? 135.474 149.644 158.514 1.00 68.80  ? 136  PHE B N   1 
ATOM   7930  C  CA  . PHE B 1 136 ? 135.436 148.394 159.263 1.00 68.80  ? 136  PHE B CA  1 
ATOM   7931  C  C   . PHE B 1 136 ? 136.807 148.035 159.816 1.00 68.80  ? 136  PHE B C   1 
ATOM   7932  O  O   . PHE B 1 136 ? 136.915 147.556 160.947 1.00 68.80  ? 136  PHE B O   1 
ATOM   7933  C  CB  . PHE B 1 136 ? 134.902 147.268 158.381 1.00 68.80  ? 136  PHE B CB  1 
ATOM   7934  C  CG  . PHE B 1 136 ? 135.276 145.895 158.859 1.00 68.80  ? 136  PHE B CG  1 
ATOM   7935  C  CD1 . PHE B 1 136 ? 134.565 145.287 159.878 1.00 68.80  ? 136  PHE B CD1 1 
ATOM   7936  C  CD2 . PHE B 1 136 ? 136.331 145.207 158.282 1.00 68.80  ? 136  PHE B CD2 1 
ATOM   7937  C  CE1 . PHE B 1 136 ? 134.902 144.024 160.320 1.00 68.80  ? 136  PHE B CE1 1 
ATOM   7938  C  CE2 . PHE B 1 136 ? 136.674 143.944 158.720 1.00 68.80  ? 136  PHE B CE2 1 
ATOM   7939  C  CZ  . PHE B 1 136 ? 135.958 143.352 159.740 1.00 68.80  ? 136  PHE B CZ  1 
ATOM   7940  N  N   . ILE B 1 137 ? 137.865 148.239 159.029 1.00 66.61  ? 137  ILE B N   1 
ATOM   7941  C  CA  . ILE B 1 137 ? 139.213 147.944 159.505 1.00 66.61  ? 137  ILE B CA  1 
ATOM   7942  C  C   . ILE B 1 137 ? 139.562 148.841 160.683 1.00 66.61  ? 137  ILE B C   1 
ATOM   7943  O  O   . ILE B 1 137 ? 140.083 148.377 161.707 1.00 66.61  ? 137  ILE B O   1 
ATOM   7944  C  CB  . ILE B 1 137 ? 140.232 148.090 158.361 1.00 66.61  ? 137  ILE B CB  1 
ATOM   7945  C  CG1 . ILE B 1 137 ? 140.152 146.888 157.417 1.00 66.61  ? 137  ILE B CG1 1 
ATOM   7946  C  CG2 . ILE B 1 137 ? 141.641 148.248 158.912 1.00 66.61  ? 137  ILE B CG2 1 
ATOM   7947  C  CD1 . ILE B 1 137 ? 141.028 147.021 156.192 1.00 66.61  ? 137  ILE B CD1 1 
ATOM   7948  N  N   . GLN B 1 138 ? 139.269 150.140 160.563 1.00 60.57  ? 138  GLN B N   1 
ATOM   7949  C  CA  . GLN B 1 138 ? 139.531 151.052 161.673 1.00 60.57  ? 138  GLN B CA  1 
ATOM   7950  C  C   . GLN B 1 138 ? 138.799 150.606 162.934 1.00 60.57  ? 138  GLN B C   1 
ATOM   7951  O  O   . GLN B 1 138 ? 139.407 150.459 164.006 1.00 60.57  ? 138  GLN B O   1 
ATOM   7952  C  CB  . GLN B 1 138 ? 139.127 152.476 161.290 1.00 60.57  ? 138  GLN B CB  1 
ATOM   7953  C  CG  . GLN B 1 138 ? 140.088 153.175 160.344 1.00 60.57  ? 138  GLN B CG  1 
ATOM   7954  C  CD  . GLN B 1 138 ? 141.307 153.737 161.054 1.00 60.57  ? 138  GLN B CD  1 
ATOM   7955  O  OE1 . GLN B 1 138 ? 141.993 153.031 161.793 1.00 60.57  ? 138  GLN B OE1 1 
ATOM   7956  N  NE2 . GLN B 1 138 ? 141.576 155.018 160.837 1.00 60.57  ? 138  GLN B NE2 1 
ATOM   7957  N  N   . GLU B 1 139 ? 137.490 150.365 162.816 1.00 60.06  ? 139  GLU B N   1 
ATOM   7958  C  CA  . GLU B 1 139 ? 136.700 149.993 163.985 1.00 60.06  ? 139  GLU B CA  1 
ATOM   7959  C  C   . GLU B 1 139 ? 137.163 148.667 164.573 1.00 60.06  ? 139  GLU B C   1 
ATOM   7960  O  O   . GLU B 1 139 ? 137.270 148.534 165.795 1.00 60.06  ? 139  GLU B O   1 
ATOM   7961  C  CB  . GLU B 1 139 ? 135.215 149.931 163.628 1.00 60.06  ? 139  GLU B CB  1 
ATOM   7962  C  CG  . GLU B 1 139 ? 134.643 151.239 163.115 1.00 60.06  ? 139  GLU B CG  1 
ATOM   7963  C  CD  . GLU B 1 139 ? 133.144 151.175 162.904 1.00 60.06  ? 139  GLU B CD  1 
ATOM   7964  O  OE1 . GLU B 1 139 ? 132.484 150.355 163.574 1.00 60.06  ? 139  GLU B OE1 1 
ATOM   7965  O  OE2 . GLU B 1 139 ? 132.625 151.946 162.070 1.00 60.06  ? 139  GLU B OE2 1 
ATOM   7966  N  N   . ALA B 1 140 ? 137.446 147.677 163.726 1.00 56.44  ? 140  ALA B N   1 
ATOM   7967  C  CA  . ALA B 1 140 ? 137.841 146.364 164.221 1.00 56.44  ? 140  ALA B CA  1 
ATOM   7968  C  C   . ALA B 1 140 ? 139.177 146.428 164.947 1.00 56.44  ? 140  ALA B C   1 
ATOM   7969  O  O   . ALA B 1 140 ? 139.325 145.865 166.038 1.00 56.44  ? 140  ALA B O   1 
ATOM   7970  C  CB  . ALA B 1 140 ? 137.902 145.365 163.067 1.00 56.44  ? 140  ALA B CB  1 
ATOM   7971  N  N   . ARG B 1 141 ? 140.163 147.116 164.363 1.00 58.14  ? 141  ARG B N   1 
ATOM   7972  C  CA  . ARG B 1 141 ? 141.457 147.239 165.024 1.00 58.14  ? 141  ARG B CA  1 
ATOM   7973  C  C   . ARG B 1 141 ? 141.326 147.958 166.360 1.00 58.14  ? 141  ARG B C   1 
ATOM   7974  O  O   . ARG B 1 141 ? 141.875 147.508 167.376 1.00 58.14  ? 141  ARG B O   1 
ATOM   7975  C  CB  . ARG B 1 141 ? 142.443 147.975 164.117 1.00 58.14  ? 141  ARG B CB  1 
ATOM   7976  C  CG  . ARG B 1 141 ? 143.438 147.069 163.415 1.00 58.14  ? 141  ARG B CG  1 
ATOM   7977  C  CD  . ARG B 1 141 ? 144.446 147.870 162.606 1.00 58.14  ? 141  ARG B CD  1 
ATOM   7978  N  NE  . ARG B 1 141 ? 145.322 148.675 163.450 1.00 58.14  ? 141  ARG B NE  1 
ATOM   7979  C  CZ  . ARG B 1 141 ? 145.190 149.981 163.638 1.00 58.14  ? 141  ARG B CZ  1 
ATOM   7980  N  NH1 . ARG B 1 141 ? 144.218 150.668 163.061 1.00 58.14  ? 141  ARG B NH1 1 
ATOM   7981  N  NH2 . ARG B 1 141 ? 146.056 150.614 164.424 1.00 58.14  ? 141  ARG B NH2 1 
ATOM   7982  N  N   . SER B 1 142 ? 140.590 149.072 166.383 1.00 50.04  ? 142  SER B N   1 
ATOM   7983  C  CA  . SER B 1 142 ? 140.474 149.832 167.622 1.00 50.04  ? 142  SER B CA  1 
ATOM   7984  C  C   . SER B 1 142 ? 139.707 149.056 168.688 1.00 50.04  ? 142  SER B C   1 
ATOM   7985  O  O   . SER B 1 142 ? 140.079 149.083 169.867 1.00 50.04  ? 142  SER B O   1 
ATOM   7986  C  CB  . SER B 1 142 ? 139.817 151.177 167.340 1.00 50.04  ? 142  SER B CB  1 
ATOM   7987  O  OG  . SER B 1 142 ? 140.491 151.864 166.302 1.00 50.04  ? 142  SER B OG  1 
ATOM   7988  N  N   . THR B 1 143 ? 138.633 148.360 168.302 1.00 47.46  ? 143  THR B N   1 
ATOM   7989  C  CA  . THR B 1 143 ? 137.881 147.565 169.267 1.00 47.46  ? 143  THR B CA  1 
ATOM   7990  C  C   . THR B 1 143 ? 138.709 146.402 169.793 1.00 47.46  ? 143  THR B C   1 
ATOM   7991  O  O   . THR B 1 143 ? 138.622 146.064 170.977 1.00 47.46  ? 143  THR B O   1 
ATOM   7992  C  CB  . THR B 1 143 ? 136.582 147.050 168.647 1.00 47.46  ? 143  THR B CB  1 
ATOM   7993  O  OG1 . THR B 1 143 ? 136.867 146.379 167.414 1.00 47.46  ? 143  THR B OG1 1 
ATOM   7994  C  CG2 . THR B 1 143 ? 135.608 148.193 168.403 1.00 47.46  ? 143  THR B CG2 1 
ATOM   7995  N  N   . LYS B 1 144 ? 139.504 145.764 168.930 1.00 47.37  ? 144  LYS B N   1 
ATOM   7996  C  CA  . LYS B 1 144 ? 140.382 144.699 169.400 1.00 47.37  ? 144  LYS B CA  1 
ATOM   7997  C  C   . LYS B 1 144 ? 141.391 145.232 170.407 1.00 47.37  ? 144  LYS B C   1 
ATOM   7998  O  O   . LYS B 1 144 ? 141.636 144.604 171.445 1.00 47.37  ? 144  LYS B O   1 
ATOM   7999  C  CB  . LYS B 1 144 ? 141.092 144.044 168.217 1.00 47.37  ? 144  LYS B CB  1 
ATOM   8000  C  CG  . LYS B 1 144 ? 141.914 142.820 168.584 1.00 47.37  ? 144  LYS B CG  1 
ATOM   8001  C  CD  . LYS B 1 144 ? 142.405 142.093 167.342 1.00 47.37  ? 144  LYS B CD  1 
ATOM   8002  C  CE  . LYS B 1 144 ? 143.242 140.879 167.707 1.00 47.37  ? 144  LYS B CE  1 
ATOM   8003  N  NZ  . LYS B 1 144 ? 144.553 141.270 168.295 1.00 47.37  ? 144  LYS B NZ  1 
ATOM   8004  N  N   . ALA B 1 145 ? 141.976 146.400 170.125 1.00 44.91  ? 145  ALA B N   1 
ATOM   8005  C  CA  . ALA B 1 145 ? 142.914 146.995 171.073 1.00 44.91  ? 145  ALA B CA  1 
ATOM   8006  C  C   . ALA B 1 145 ? 142.230 147.325 172.395 1.00 44.91  ? 145  ALA B C   1 
ATOM   8007  O  O   . ALA B 1 145 ? 142.782 147.062 173.471 1.00 44.91  ? 145  ALA B O   1 
ATOM   8008  C  CB  . ALA B 1 145 ? 143.550 148.246 170.470 1.00 44.91  ? 145  ALA B CB  1 
ATOM   8009  N  N   . ALA B 1 146 ? 141.024 147.893 172.335 1.00 41.65  ? 146  ALA B N   1 
ATOM   8010  C  CA  . ALA B 1 146 ? 140.309 148.253 173.556 1.00 41.65  ? 146  ALA B CA  1 
ATOM   8011  C  C   . ALA B 1 146 ? 139.943 147.020 174.373 1.00 41.65  ? 146  ALA B C   1 
ATOM   8012  O  O   . ALA B 1 146 ? 140.049 147.027 175.605 1.00 41.65  ? 146  ALA B O   1 
ATOM   8013  C  CB  . ALA B 1 146 ? 139.058 149.060 173.213 1.00 41.65  ? 146  ALA B CB  1 
ATOM   8014  N  N   . ASP B 1 147 ? 139.503 145.952 173.705 1.00 42.69  ? 147  ASP B N   1 
ATOM   8015  C  CA  . ASP B 1 147 ? 139.162 144.722 174.411 1.00 42.69  ? 147  ASP B CA  1 
ATOM   8016  C  C   . ASP B 1 147 ? 140.396 144.087 175.036 1.00 42.69  ? 147  ASP B C   1 
ATOM   8017  O  O   . ASP B 1 147 ? 140.333 143.567 176.156 1.00 42.69  ? 147  ASP B O   1 
ATOM   8018  C  CB  . ASP B 1 147 ? 138.471 143.747 173.461 1.00 42.69  ? 147  ASP B CB  1 
ATOM   8019  C  CG  . ASP B 1 147 ? 137.021 144.107 173.212 1.00 42.69  ? 147  ASP B CG  1 
ATOM   8020  O  OD1 . ASP B 1 147 ? 136.466 144.911 173.991 1.00 42.69  ? 147  ASP B OD1 1 
ATOM   8021  O  OD2 . ASP B 1 147 ? 136.435 143.590 172.238 1.00 42.69  ? 147  ASP B OD2 1 
ATOM   8022  N  N   . ALA B 1 148 ? 141.530 144.120 174.331 1.00 42.50  ? 148  ALA B N   1 
ATOM   8023  C  CA  . ALA B 1 148 ? 142.770 143.628 174.921 1.00 42.50  ? 148  ALA B CA  1 
ATOM   8024  C  C   . ALA B 1 148 ? 143.152 144.442 176.151 1.00 42.50  ? 148  ALA B C   1 
ATOM   8025  O  O   . ALA B 1 148 ? 143.580 143.882 177.168 1.00 42.50  ? 148  ALA B O   1 
ATOM   8026  C  CB  . ALA B 1 148 ? 143.893 143.657 173.886 1.00 42.50  ? 148  ALA B CB  1 
ATOM   8027  N  N   . LEU B 1 149 ? 143.002 145.767 176.077 1.00 39.10  ? 149  LEU B N   1 
ATOM   8028  C  CA  . LEU B 1 149 ? 143.318 146.610 177.226 1.00 39.10  ? 149  LEU B CA  1 
ATOM   8029  C  C   . LEU B 1 149 ? 142.407 146.299 178.406 1.00 39.10  ? 149  LEU B C   1 
ATOM   8030  O  O   . LEU B 1 149 ? 142.866 146.232 179.552 1.00 39.10  ? 149  LEU B O   1 
ATOM   8031  C  CB  . LEU B 1 149 ? 143.212 148.084 176.845 1.00 39.10  ? 149  LEU B CB  1 
ATOM   8032  C  CG  . LEU B 1 149 ? 144.254 148.580 175.842 1.00 39.10  ? 149  LEU B CG  1 
ATOM   8033  C  CD1 . LEU B 1 149 ? 144.211 150.095 175.720 1.00 39.10  ? 149  LEU B CD1 1 
ATOM   8034  C  CD2 . LEU B 1 149 ? 145.644 148.092 176.217 1.00 39.10  ? 149  LEU B CD2 1 
ATOM   8035  N  N   . LYS B 1 150 ? 141.112 146.110 178.146 1.00 36.33  ? 150  LYS B N   1 
ATOM   8036  C  CA  . LYS B 1 150 ? 140.182 145.762 179.214 1.00 36.33  ? 150  LYS B CA  1 
ATOM   8037  C  C   . LYS B 1 150 ? 140.464 144.385 179.798 1.00 36.33  ? 150  LYS B C   1 
ATOM   8038  O  O   . LYS B 1 150 ? 140.224 144.170 180.990 1.00 36.33  ? 150  LYS B O   1 
ATOM   8039  C  CB  . LYS B 1 150 ? 138.743 145.824 178.703 1.00 36.33  ? 150  LYS B CB  1 
ATOM   8040  C  CG  . LYS B 1 150 ? 137.694 145.814 179.802 1.00 36.33  ? 150  LYS B CG  1 
ATOM   8041  C  CD  . LYS B 1 150 ? 136.289 145.805 179.225 1.00 36.33  ? 150  LYS B CD  1 
ATOM   8042  C  CE  . LYS B 1 150 ? 135.254 146.135 180.287 1.00 36.33  ? 150  LYS B CE  1 
ATOM   8043  N  NZ  . LYS B 1 150 ? 135.215 145.104 181.361 1.00 36.33  ? 150  LYS B NZ  1 
ATOM   8044  N  N   . ALA B 1 151 ? 140.966 143.452 178.990 1.00 42.32  ? 151  ALA B N   1 
ATOM   8045  C  CA  . ALA B 1 151 ? 141.325 142.132 179.488 1.00 42.32  ? 151  ALA B CA  1 
ATOM   8046  C  C   . ALA B 1 151 ? 142.685 142.100 180.169 1.00 42.32  ? 151  ALA B C   1 
ATOM   8047  O  O   . ALA B 1 151 ? 142.995 141.119 180.853 1.00 42.32  ? 151  ALA B O   1 
ATOM   8048  C  CB  . ALA B 1 151 ? 141.306 141.111 178.346 1.00 42.32  ? 151  ALA B CB  1 
ATOM   8049  N  N   . MET B 1 152 ? 143.507 143.138 179.988 1.00 44.30  ? 152  MET B N   1 
ATOM   8050  C  CA  . MET B 1 152 ? 144.786 143.194 180.690 1.00 44.30  ? 152  MET B CA  1 
ATOM   8051  C  C   . MET B 1 152 ? 144.588 143.252 182.199 1.00 44.30  ? 152  MET B C   1 
ATOM   8052  O  O   . MET B 1 152 ? 145.277 142.553 182.950 1.00 44.30  ? 152  MET B O   1 
ATOM   8053  C  CB  . MET B 1 152 ? 145.602 144.395 180.216 1.00 44.30  ? 152  MET B CB  1 
ATOM   8054  C  CG  . MET B 1 152 ? 146.257 144.212 178.861 1.00 44.30  ? 152  MET B CG  1 
ATOM   8055  S  SD  . MET B 1 152 ? 147.245 145.641 178.380 1.00 44.30  ? 152  MET B SD  1 
ATOM   8056  C  CE  . MET B 1 152 ? 148.478 145.654 179.679 1.00 44.30  ? 152  MET B CE  1 
ATOM   8057  N  N   . VAL B 1 153 ? 143.656 144.083 182.663 1.00 42.93  ? 153  VAL B N   1 
ATOM   8058  C  CA  . VAL B 1 153 ? 143.357 144.172 184.088 1.00 42.93  ? 153  VAL B CA  1 
ATOM   8059  C  C   . VAL B 1 153 ? 141.957 143.630 184.355 1.00 42.93  ? 153  VAL B C   1 
ATOM   8060  O  O   . VAL B 1 153 ? 140.963 144.362 184.305 1.00 42.93  ? 153  VAL B O   1 
ATOM   8061  C  CB  . VAL B 1 153 ? 143.529 145.615 184.603 1.00 42.93  ? 153  VAL B CB  1 
ATOM   8062  C  CG1 . VAL B 1 153 ? 145.002 145.975 184.651 1.00 42.93  ? 153  VAL B CG1 1 
ATOM   8063  C  CG2 . VAL B 1 153 ? 142.803 146.604 183.703 1.00 42.93  ? 153  VAL B CG2 1 
ATOM   8064  N  N   . SER B 1 154 ? 141.873 142.337 184.648 1.00 50.65  ? 154  SER B N   1 
ATOM   8065  C  CA  . SER B 1 154 ? 140.608 141.674 184.920 1.00 50.65  ? 154  SER B CA  1 
ATOM   8066  C  C   . SER B 1 154 ? 140.746 140.831 186.176 1.00 50.65  ? 154  SER B C   1 
ATOM   8067  O  O   . SER B 1 154 ? 141.822 140.295 186.457 1.00 50.65  ? 154  SER B O   1 
ATOM   8068  C  CB  . SER B 1 154 ? 140.172 140.795 183.742 1.00 50.65  ? 154  SER B CB  1 
ATOM   8069  O  OG  . SER B 1 154 ? 138.834 140.361 183.902 1.00 50.65  ? 154  SER B OG  1 
ATOM   8070  N  N   . ASN B 1 155 ? 139.656 140.728 186.934 1.00 57.12  ? 155  ASN B N   1 
ATOM   8071  C  CA  . ASN B 1 155 ? 139.670 139.932 188.154 1.00 57.12  ? 155  ASN B CA  1 
ATOM   8072  C  C   . ASN B 1 155 ? 139.980 138.478 187.829 1.00 57.12  ? 155  ASN B C   1 
ATOM   8073  O  O   . ASN B 1 155 ? 139.399 137.896 186.909 1.00 57.12  ? 155  ASN B O   1 
ATOM   8074  C  CB  . ASN B 1 155 ? 138.325 140.042 188.870 1.00 57.12  ? 155  ASN B CB  1 
ATOM   8075  C  CG  . ASN B 1 155 ? 138.192 141.325 189.661 1.00 57.12  ? 155  ASN B CG  1 
ATOM   8076  O  OD1 . ASN B 1 155 ? 139.159 142.067 189.829 1.00 57.12  ? 155  ASN B OD1 1 
ATOM   8077  N  ND2 . ASN B 1 155 ? 136.989 141.595 190.151 1.00 57.12  ? 155  ASN B ND2 1 
ATOM   8078  N  N   . THR B 1 156 ? 140.904 137.896 188.583 1.00 68.02  ? 156  THR B N   1 
ATOM   8079  C  CA  . THR B 1 156 ? 141.335 136.523 188.376 1.00 68.02  ? 156  THR B CA  1 
ATOM   8080  C  C   . THR B 1 156 ? 140.937 135.659 189.565 1.00 68.02  ? 156  THR B C   1 
ATOM   8081  O  O   . THR B 1 156 ? 140.681 136.146 190.669 1.00 68.02  ? 156  THR B O   1 
ATOM   8082  C  CB  . THR B 1 156 ? 142.851 136.451 188.157 1.00 68.02  ? 156  THR B CB  1 
ATOM   8083  O  OG1 . THR B 1 156 ? 143.529 136.742 189.385 1.00 68.02  ? 156  THR B OG1 1 
ATOM   8084  C  CG2 . THR B 1 156 ? 143.286 137.447 187.094 1.00 68.02  ? 156  THR B CG2 1 
ATOM   8085  N  N   . ALA B 1 157 ? 140.890 134.355 189.317 1.00 73.16  ? 157  ALA B N   1 
ATOM   8086  C  CA  . ALA B 1 157 ? 140.563 133.370 190.332 1.00 73.16  ? 157  ALA B CA  1 
ATOM   8087  C  C   . ALA B 1 157 ? 141.565 132.228 190.264 1.00 73.16  ? 157  ALA B C   1 
ATOM   8088  O  O   . ALA B 1 157 ? 142.138 131.941 189.207 1.00 73.16  ? 157  ALA B O   1 
ATOM   8089  C  CB  . ALA B 1 157 ? 139.138 132.829 190.160 1.00 73.16  ? 157  ALA B CB  1 
ATOM   8090  N  N   . THR B 1 158 ? 141.767 131.578 191.405 1.00 78.97  ? 158  THR B N   1 
ATOM   8091  C  CA  . THR B 1 158 ? 142.700 130.466 191.514 1.00 78.97  ? 158  THR B CA  1 
ATOM   8092  C  C   . THR B 1 158 ? 141.926 129.158 191.395 1.00 78.97  ? 158  THR B C   1 
ATOM   8093  O  O   . THR B 1 158 ? 141.024 128.890 192.195 1.00 78.97  ? 158  THR B O   1 
ATOM   8094  C  CB  . THR B 1 158 ? 143.459 130.529 192.838 1.00 78.97  ? 158  THR B CB  1 
ATOM   8095  O  OG1 . THR B 1 158 ? 144.015 131.839 193.007 1.00 78.97  ? 158  THR B OG1 1 
ATOM   8096  C  CG2 . THR B 1 158 ? 144.583 129.517 192.846 1.00 78.97  ? 158  THR B CG2 1 
ATOM   8097  N  N   . VAL B 1 159 ? 142.281 128.349 190.401 1.00 84.03  ? 159  VAL B N   1 
ATOM   8098  C  CA  . VAL B 1 159 ? 141.546 127.133 190.080 1.00 84.03  ? 159  VAL B CA  1 
ATOM   8099  C  C   . VAL B 1 159 ? 142.492 125.943 190.127 1.00 84.03  ? 159  VAL B C   1 
ATOM   8100  O  O   . VAL B 1 159 ? 143.703 126.077 189.924 1.00 84.03  ? 159  VAL B O   1 
ATOM   8101  C  CB  . VAL B 1 159 ? 140.871 127.228 188.695 1.00 84.03  ? 159  VAL B CB  1 
ATOM   8102  C  CG1 . VAL B 1 159 ? 139.701 128.190 188.740 1.00 84.03  ? 159  VAL B CG1 1 
ATOM   8103  C  CG2 . VAL B 1 159 ? 141.883 127.666 187.654 1.00 84.03  ? 159  VAL B CG2 1 
ATOM   8104  N  N   . LEU B 1 160 ? 141.927 124.770 190.409 1.00 93.39  ? 160  LEU B N   1 
ATOM   8105  C  CA  . LEU B 1 160 ? 142.694 123.531 190.412 1.00 93.39  ? 160  LEU B CA  1 
ATOM   8106  C  C   . LEU B 1 160 ? 143.220 123.204 189.020 1.00 93.39  ? 160  LEU B C   1 
ATOM   8107  O  O   . LEU B 1 160 ? 144.435 123.198 188.795 1.00 93.39  ? 160  LEU B O   1 
ATOM   8108  C  CB  . LEU B 1 160 ? 141.838 122.375 190.933 1.00 93.39  ? 160  LEU B CB  1 
ATOM   8109  C  CG  . LEU B 1 160 ? 141.958 122.050 192.422 1.00 93.39  ? 160  LEU B CG  1 
ATOM   8110  C  CD1 . LEU B 1 160 ? 140.922 121.015 192.827 1.00 93.39  ? 160  LEU B CD1 1 
ATOM   8111  C  CD2 . LEU B 1 160 ? 143.360 121.565 192.753 1.00 93.39  ? 160  LEU B CD2 1 
ATOM   8112  N  N   . ARG B 1 161 ? 142.305 122.941 188.083 1.00 100.67 ? 161  ARG B N   1 
ATOM   8113  C  CA  . ARG B 1 161 ? 142.634 122.578 186.707 1.00 100.67 ? 161  ARG B CA  1 
ATOM   8114  C  C   . ARG B 1 161 ? 143.596 121.397 186.626 1.00 100.67 ? 161  ARG B C   1 
ATOM   8115  O  O   . ARG B 1 161 ? 143.803 120.679 187.610 1.00 100.67 ? 161  ARG B O   1 
ATOM   8116  C  CB  . ARG B 1 161 ? 143.219 123.779 185.959 1.00 100.67 ? 161  ARG B CB  1 
ATOM   8117  C  CG  . ARG B 1 161 ? 142.183 124.799 185.514 1.00 100.67 ? 161  ARG B CG  1 
ATOM   8118  C  CD  . ARG B 1 161 ? 140.911 124.120 185.024 1.00 100.67 ? 161  ARG B CD  1 
ATOM   8119  N  NE  . ARG B 1 161 ? 139.792 125.047 184.912 1.00 100.67 ? 161  ARG B NE  1 
ATOM   8120  C  CZ  . ARG B 1 161 ? 139.680 125.983 183.978 1.00 100.67 ? 161  ARG B CZ  1 
ATOM   8121  N  NH1 . ARG B 1 161 ? 140.599 126.138 183.040 1.00 100.67 ? 161  ARG B NH1 1 
ATOM   8122  N  NH2 . ARG B 1 161 ? 138.615 126.780 183.983 1.00 100.67 ? 161  ARG B NH2 1 
ATOM   8123  N  N   . VAL B 1 162 ? 144.172 121.183 185.446 1.00 112.56 ? 162  VAL B N   1 
ATOM   8124  C  CA  . VAL B 1 162 ? 145.133 120.112 185.211 1.00 112.56 ? 162  VAL B CA  1 
ATOM   8125  C  C   . VAL B 1 162 ? 146.311 120.690 184.440 1.00 112.56 ? 162  VAL B C   1 
ATOM   8126  O  O   . VAL B 1 162 ? 146.127 121.416 183.458 1.00 112.56 ? 162  VAL B O   1 
ATOM   8127  C  CB  . VAL B 1 162 ? 144.495 118.932 184.447 1.00 112.56 ? 162  VAL B CB  1 
ATOM   8128  C  CG1 . VAL B 1 162 ? 145.560 117.946 183.995 1.00 112.56 ? 162  VAL B CG1 1 
ATOM   8129  C  CG2 . VAL B 1 162 ? 143.462 118.233 185.317 1.00 112.56 ? 162  VAL B CG2 1 
ATOM   8130  N  N   . ILE B 1 163 ? 147.522 120.367 184.886 1.00 119.66 ? 163  ILE B N   1 
ATOM   8131  C  CA  . ILE B 1 163 ? 148.751 120.859 184.275 1.00 119.66 ? 163  ILE B CA  1 
ATOM   8132  C  C   . ILE B 1 163 ? 149.426 119.707 183.547 1.00 119.66 ? 163  ILE B C   1 
ATOM   8133  O  O   . ILE B 1 163 ? 149.597 118.621 184.116 1.00 119.66 ? 163  ILE B O   1 
ATOM   8134  C  CB  . ILE B 1 163 ? 149.696 121.477 185.320 1.00 119.66 ? 163  ILE B CB  1 
ATOM   8135  C  CG1 . ILE B 1 163 ? 148.993 122.605 186.075 1.00 119.66 ? 163  ILE B CG1 1 
ATOM   8136  C  CG2 . ILE B 1 163 ? 150.964 121.988 184.655 1.00 119.66 ? 163  ILE B CG2 1 
ATOM   8137  C  CD1 . ILE B 1 163 ? 149.892 123.339 187.044 1.00 119.66 ? 163  ILE B CD1 1 
ATOM   8138  N  N   . ASN B 1 164 ? 149.789 119.942 182.284 1.00 131.33 ? 164  ASN B N   1 
ATOM   8139  C  CA  . ASN B 1 164 ? 150.547 119.001 181.465 1.00 131.33 ? 164  ASN B CA  1 
ATOM   8140  C  C   . ASN B 1 164 ? 149.762 117.725 181.179 1.00 131.33 ? 164  ASN B C   1 
ATOM   8141  O  O   . ASN B 1 164 ? 148.644 117.544 181.674 1.00 131.33 ? 164  ASN B O   1 
ATOM   8142  C  CB  . ASN B 1 164 ? 151.883 118.662 182.133 1.00 131.33 ? 164  ASN B CB  1 
ATOM   8143  C  CG  . ASN B 1 164 ? 153.032 118.615 181.147 1.00 131.33 ? 164  ASN B CG  1 
ATOM   8144  O  OD1 . ASN B 1 164 ? 152.832 118.409 179.950 1.00 131.33 ? 164  ASN B OD1 1 
ATOM   8145  N  ND2 . ASN B 1 164 ? 154.247 118.810 181.646 1.00 131.33 ? 164  ASN B ND2 1 
ATOM   8146  N  N   . ASP B 1 165 ? 150.343 116.839 180.368 1.00 135.23 ? 165  ASP B N   1 
ATOM   8147  C  CA  . ASP B 1 165 ? 149.681 115.587 180.019 1.00 135.23 ? 165  ASP B CA  1 
ATOM   8148  C  C   . ASP B 1 165 ? 149.741 114.568 181.149 1.00 135.23 ? 165  ASP B C   1 
ATOM   8149  O  O   . ASP B 1 165 ? 148.948 113.619 181.163 1.00 135.23 ? 165  ASP B O   1 
ATOM   8150  C  CB  . ASP B 1 165 ? 150.306 115.002 178.752 1.00 135.23 ? 165  ASP B CB  1 
ATOM   8151  C  CG  . ASP B 1 165 ? 151.816 114.883 178.848 1.00 135.23 ? 165  ASP B CG  1 
ATOM   8152  O  OD1 . ASP B 1 165 ? 152.389 115.351 179.854 1.00 135.23 ? 165  ASP B OD1 1 
ATOM   8153  O  OD2 . ASP B 1 165 ? 152.429 114.322 177.916 1.00 135.23 ? 165  ASP B OD2 1 
ATOM   8154  N  N   . LYS B 1 166 ? 150.667 114.740 182.095 1.00 128.95 ? 166  LYS B N   1 
ATOM   8155  C  CA  . LYS B 1 166 ? 150.799 113.781 183.187 1.00 128.95 ? 166  LYS B CA  1 
ATOM   8156  C  C   . LYS B 1 166 ? 149.602 113.823 184.128 1.00 128.95 ? 166  LYS B C   1 
ATOM   8157  O  O   . LYS B 1 166 ? 149.417 112.906 184.936 1.00 128.95 ? 166  LYS B O   1 
ATOM   8158  C  CB  . LYS B 1 166 ? 152.091 114.042 183.963 1.00 128.95 ? 166  LYS B CB  1 
ATOM   8159  N  N   . GLY B 1 167 ? 148.785 114.869 184.045 1.00 123.44 ? 167  GLY B N   1 
ATOM   8160  C  CA  . GLY B 1 167 ? 147.648 115.015 184.926 1.00 123.44 ? 167  GLY B CA  1 
ATOM   8161  C  C   . GLY B 1 167 ? 147.940 115.694 186.243 1.00 123.44 ? 167  GLY B C   1 
ATOM   8162  O  O   . GLY B 1 167 ? 147.079 115.679 187.131 1.00 123.44 ? 167  GLY B O   1 
ATOM   8163  N  N   . GLU B 1 168 ? 149.123 116.282 186.401 1.00 121.26 ? 168  GLU B N   1 
ATOM   8164  C  CA  . GLU B 1 168 ? 149.468 116.964 187.639 1.00 121.26 ? 168  GLU B CA  1 
ATOM   8165  C  C   . GLU B 1 168 ? 148.569 118.176 187.855 1.00 121.26 ? 168  GLU B C   1 
ATOM   8166  O  O   . GLU B 1 168 ? 148.191 118.877 186.912 1.00 121.26 ? 168  GLU B O   1 
ATOM   8167  C  CB  . GLU B 1 168 ? 150.934 117.396 187.620 1.00 121.26 ? 168  GLU B CB  1 
ATOM   8168  N  N   . ASN B 1 169 ? 148.224 118.416 189.115 1.00 112.79 ? 169  ASN B N   1 
ATOM   8169  C  CA  . ASN B 1 169 ? 147.322 119.495 189.487 1.00 112.79 ? 169  ASN B CA  1 
ATOM   8170  C  C   . ASN B 1 169 ? 148.091 120.625 190.155 1.00 112.79 ? 169  ASN B C   1 
ATOM   8171  O  O   . ASN B 1 169 ? 148.952 120.389 191.008 1.00 112.79 ? 169  ASN B O   1 
ATOM   8172  C  CB  . ASN B 1 169 ? 146.227 118.988 190.425 1.00 112.79 ? 169  ASN B CB  1 
ATOM   8173  C  CG  . ASN B 1 169 ? 145.150 118.217 189.696 1.00 112.79 ? 169  ASN B CG  1 
ATOM   8174  O  OD1 . ASN B 1 169 ? 145.172 118.104 188.470 1.00 112.79 ? 169  ASN B OD1 1 
ATOM   8175  N  ND2 . ASN B 1 169 ? 144.201 117.677 190.447 1.00 112.79 ? 169  ASN B ND2 1 
ATOM   8176  N  N   . GLY B 1 170 ? 147.772 121.854 189.761 1.00 97.45  ? 170  GLY B N   1 
ATOM   8177  C  CA  . GLY B 1 170 ? 148.352 123.048 190.331 1.00 97.45  ? 170  GLY B CA  1 
ATOM   8178  C  C   . GLY B 1 170 ? 147.269 124.019 190.761 1.00 97.45  ? 170  GLY B C   1 
ATOM   8179  O  O   . GLY B 1 170 ? 146.154 123.630 191.115 1.00 97.45  ? 170  GLY B O   1 
ATOM   8180  N  N   . TRP B 1 171 ? 147.617 125.304 190.726 1.00 84.74  ? 171  TRP B N   1 
ATOM   8181  C  CA  . TRP B 1 171 ? 146.688 126.378 191.087 1.00 84.74  ? 171  TRP B CA  1 
ATOM   8182  C  C   . TRP B 1 171 ? 146.869 127.497 190.063 1.00 84.74  ? 171  TRP B C   1 
ATOM   8183  O  O   . TRP B 1 171 ? 147.702 128.390 190.240 1.00 84.74  ? 171  TRP B O   1 
ATOM   8184  C  CB  . TRP B 1 171 ? 146.928 126.858 192.511 1.00 84.74  ? 171  TRP B CB  1 
ATOM   8185  C  CG  . TRP B 1 171 ? 146.417 125.906 193.550 1.00 84.74  ? 171  TRP B CG  1 
ATOM   8186  C  CD1 . TRP B 1 171 ? 147.164 125.115 194.372 1.00 84.74  ? 171  TRP B CD1 1 
ATOM   8187  C  CD2 . TRP B 1 171 ? 145.047 125.635 193.870 1.00 84.74  ? 171  TRP B CD2 1 
ATOM   8188  N  NE1 . TRP B 1 171 ? 146.346 124.374 195.189 1.00 84.74  ? 171  TRP B NE1 1 
ATOM   8189  C  CE2 . TRP B 1 171 ? 145.041 124.674 194.900 1.00 84.74  ? 171  TRP B CE2 1 
ATOM   8190  C  CE3 . TRP B 1 171 ? 143.825 126.113 193.388 1.00 84.74  ? 171  TRP B CE3 1 
ATOM   8191  C  CZ2 . TRP B 1 171 ? 143.863 124.183 195.455 1.00 84.74  ? 171  TRP B CZ2 1 
ATOM   8192  C  CZ3 . TRP B 1 171 ? 142.656 125.625 193.941 1.00 84.74  ? 171  TRP B CZ3 1 
ATOM   8193  C  CH2 . TRP B 1 171 ? 142.684 124.670 194.964 1.00 84.74  ? 171  TRP B CH2 1 
ATOM   8194  N  N   . LEU B 1 172 ? 146.083 127.439 188.992 1.00 82.89  ? 172  LEU B N   1 
ATOM   8195  C  CA  . LEU B 1 172 ? 146.187 128.396 187.901 1.00 82.89  ? 172  LEU B CA  1 
ATOM   8196  C  C   . LEU B 1 172 ? 145.416 129.666 188.230 1.00 82.89  ? 172  LEU B C   1 
ATOM   8197  O  O   . LEU B 1 172 ? 144.306 129.614 188.765 1.00 82.89  ? 172  LEU B O   1 
ATOM   8198  C  CB  . LEU B 1 172 ? 145.657 127.793 186.599 1.00 82.89  ? 172  LEU B CB  1 
ATOM   8199  C  CG  . LEU B 1 172 ? 146.635 127.014 185.715 1.00 82.89  ? 172  LEU B CG  1 
ATOM   8200  C  CD1 . LEU B 1 172 ? 147.785 127.905 185.273 1.00 82.89  ? 172  LEU B CD1 1 
ATOM   8201  C  CD2 . LEU B 1 172 ? 147.151 125.771 186.421 1.00 82.89  ? 172  LEU B CD2 1 
ATOM   8202  N  N   . GLU B 1 173 ? 146.017 130.809 187.905 1.00 81.63  ? 173  GLU B N   1 
ATOM   8203  C  CA  . GLU B 1 173 ? 145.360 132.107 188.039 1.00 81.63  ? 173  GLU B CA  1 
ATOM   8204  C  C   . GLU B 1 173 ? 144.722 132.440 186.697 1.00 81.63  ? 173  GLU B C   1 
ATOM   8205  O  O   . GLU B 1 173 ? 145.396 132.905 185.774 1.00 81.63  ? 173  GLU B O   1 
ATOM   8206  C  CB  . GLU B 1 173 ? 146.358 133.178 188.466 1.00 81.63  ? 173  GLU B CB  1 
ATOM   8207  C  CG  . GLU B 1 173 ? 146.964 132.961 189.844 1.00 81.63  ? 173  GLU B CG  1 
ATOM   8208  C  CD  . GLU B 1 173 ? 146.112 133.535 190.961 1.00 81.63  ? 173  GLU B CD  1 
ATOM   8209  O  OE1 . GLU B 1 173 ? 144.870 133.539 190.831 1.00 81.63  ? 173  GLU B OE1 1 
ATOM   8210  O  OE2 . GLU B 1 173 ? 146.687 133.987 191.972 1.00 81.63  ? 173  GLU B OE2 1 
ATOM   8211  N  N   . ILE B 1 174 ? 143.419 132.205 186.582 1.00 77.72  ? 174  ILE B N   1 
ATOM   8212  C  CA  . ILE B 1 174 ? 142.732 132.392 185.305 1.00 77.72  ? 174  ILE B CA  1 
ATOM   8213  C  C   . ILE B 1 174 ? 141.702 133.508 185.430 1.00 77.72  ? 174  ILE B C   1 
ATOM   8214  O  O   . ILE B 1 174 ? 141.153 133.726 186.519 1.00 77.72  ? 174  ILE B O   1 
ATOM   8215  C  CB  . ILE B 1 174 ? 142.074 131.087 184.829 1.00 77.72  ? 174  ILE B CB  1 
ATOM   8216  C  CG1 . ILE B 1 174 ? 140.964 130.662 185.792 1.00 77.72  ? 174  ILE B CG1 1 
ATOM   8217  C  CG2 . ILE B 1 174 ? 143.111 129.987 184.696 1.00 77.72  ? 174  ILE B CG2 1 
ATOM   8218  C  CD1 . ILE B 1 174 ? 139.999 129.657 185.204 1.00 77.72  ? 174  ILE B CD1 1 
ATOM   8219  N  N   . PRO B 1 175 ? 141.417 134.242 184.355 1.00 78.48  ? 175  PRO B N   1 
ATOM   8220  C  CA  . PRO B 1 175 ? 140.371 135.269 184.423 1.00 78.48  ? 175  PRO B CA  1 
ATOM   8221  C  C   . PRO B 1 175 ? 139.017 134.654 184.745 1.00 78.48  ? 175  PRO B C   1 
ATOM   8222  O  O   . PRO B 1 175 ? 138.727 133.511 184.385 1.00 78.48  ? 175  PRO B O   1 
ATOM   8223  C  CB  . PRO B 1 175 ? 140.386 135.890 183.023 1.00 78.48  ? 175  PRO B CB  1 
ATOM   8224  C  CG  . PRO B 1 175 ? 141.734 135.582 182.474 1.00 78.48  ? 175  PRO B CG  1 
ATOM   8225  C  CD  . PRO B 1 175 ? 142.178 134.294 183.095 1.00 78.48  ? 175  PRO B CD  1 
ATOM   8226  N  N   . ILE B 1 176 ? 138.185 135.434 185.439 1.00 79.34  ? 176  ILE B N   1 
ATOM   8227  C  CA  . ILE B 1 176 ? 136.903 134.932 185.922 1.00 79.34  ? 176  ILE B CA  1 
ATOM   8228  C  C   . ILE B 1 176 ? 135.975 134.529 184.785 1.00 79.34  ? 176  ILE B C   1 
ATOM   8229  O  O   . ILE B 1 176 ? 135.113 133.664 184.972 1.00 79.34  ? 176  ILE B O   1 
ATOM   8230  C  CB  . ILE B 1 176 ? 136.223 135.978 186.829 1.00 79.34  ? 176  ILE B CB  1 
ATOM   8231  C  CG1 . ILE B 1 176 ? 136.131 137.328 186.118 1.00 79.34  ? 176  ILE B CG1 1 
ATOM   8232  C  CG2 . ILE B 1 176 ? 136.976 136.114 188.140 1.00 79.34  ? 176  ILE B CG2 1 
ATOM   8233  C  CD1 . ILE B 1 176 ? 135.321 138.357 186.873 1.00 79.34  ? 176  ILE B CD1 1 
ATOM   8234  N  N   . ASP B 1 177 ? 136.124 135.136 183.606 1.00 87.29  ? 177  ASP B N   1 
ATOM   8235  C  CA  . ASP B 1 177 ? 135.246 134.805 182.489 1.00 87.29  ? 177  ASP B CA  1 
ATOM   8236  C  C   . ASP B 1 177 ? 135.486 133.398 181.955 1.00 87.29  ? 177  ASP B C   1 
ATOM   8237  O  O   . ASP B 1 177 ? 134.642 132.876 181.219 1.00 87.29  ? 177  ASP B O   1 
ATOM   8238  C  CB  . ASP B 1 177 ? 135.411 135.832 181.367 1.00 87.29  ? 177  ASP B CB  1 
ATOM   8239  C  CG  . ASP B 1 177 ? 136.839 135.929 180.866 1.00 87.29  ? 177  ASP B CG  1 
ATOM   8240  O  OD1 . ASP B 1 177 ? 137.723 135.266 181.444 1.00 87.29  ? 177  ASP B OD1 1 
ATOM   8241  O  OD2 . ASP B 1 177 ? 137.078 136.675 179.893 1.00 87.29  ? 177  ASP B OD2 1 
ATOM   8242  N  N   . GLN B 1 178 ? 136.608 132.773 182.310 1.00 84.06  ? 178  GLN B N   1 
ATOM   8243  C  CA  . GLN B 1 178 ? 136.912 131.418 181.870 1.00 84.06  ? 178  GLN B CA  1 
ATOM   8244  C  C   . GLN B 1 178 ? 136.339 130.351 182.794 1.00 84.06  ? 178  GLN B C   1 
ATOM   8245  O  O   . GLN B 1 178 ? 136.532 129.159 182.530 1.00 84.06  ? 178  GLN B O   1 
ATOM   8246  C  CB  . GLN B 1 178 ? 138.428 131.234 181.754 1.00 84.06  ? 178  GLN B CB  1 
ATOM   8247  C  CG  . GLN B 1 178 ? 139.067 132.034 180.632 1.00 84.06  ? 178  GLN B CG  1 
ATOM   8248  C  CD  . GLN B 1 178 ? 140.565 131.822 180.546 1.00 84.06  ? 178  GLN B CD  1 
ATOM   8249  O  OE1 . GLN B 1 178 ? 141.073 130.755 180.890 1.00 84.06  ? 178  GLN B OE1 1 
ATOM   8250  N  NE2 . GLN B 1 178 ? 141.282 132.840 180.085 1.00 84.06  ? 178  GLN B NE2 1 
ATOM   8251  N  N   . LEU B 1 179 ? 135.650 130.744 183.862 1.00 85.23  ? 179  LEU B N   1 
ATOM   8252  C  CA  . LEU B 1 179 ? 135.104 129.782 184.812 1.00 85.23  ? 179  LEU B CA  1 
ATOM   8253  C  C   . LEU B 1 179 ? 133.934 129.028 184.193 1.00 85.23  ? 179  LEU B C   1 
ATOM   8254  O  O   . LEU B 1 179 ? 133.140 129.603 183.443 1.00 85.23  ? 179  LEU B O   1 
ATOM   8255  C  CB  . LEU B 1 179 ? 134.663 130.492 186.089 1.00 85.23  ? 179  LEU B CB  1 
ATOM   8256  C  CG  . LEU B 1 179 ? 135.779 130.994 187.005 1.00 85.23  ? 179  LEU B CG  1 
ATOM   8257  C  CD1 . LEU B 1 179 ? 135.193 131.668 188.232 1.00 85.23  ? 179  LEU B CD1 1 
ATOM   8258  C  CD2 . LEU B 1 179 ? 136.694 129.850 187.404 1.00 85.23  ? 179  LEU B CD2 1 
ATOM   8259  N  N   . VAL B 1 180 ? 133.834 127.740 184.506 1.00 90.30  ? 180  VAL B N   1 
ATOM   8260  C  CA  . VAL B 1 180 ? 132.724 126.902 184.058 1.00 90.30  ? 180  VAL B CA  1 
ATOM   8261  C  C   . VAL B 1 180 ? 132.034 126.326 185.289 1.00 90.30  ? 180  VAL B C   1 
ATOM   8262  O  O   . VAL B 1 180 ? 132.652 126.249 186.361 1.00 90.30  ? 180  VAL B O   1 
ATOM   8263  C  CB  . VAL B 1 180 ? 133.209 125.791 183.112 1.00 90.30  ? 180  VAL B CB  1 
ATOM   8264  C  CG1 . VAL B 1 180 ? 134.016 126.384 181.968 1.00 90.30  ? 180  VAL B CG1 1 
ATOM   8265  C  CG2 . VAL B 1 180 ? 134.029 124.761 183.874 1.00 90.30  ? 180  VAL B CG2 1 
ATOM   8266  N  N   . PRO B 1 181 ? 130.763 125.932 185.200 1.00 91.49  ? 181  PRO B N   1 
ATOM   8267  C  CA  . PRO B 1 181 ? 130.106 125.315 186.358 1.00 91.49  ? 181  PRO B CA  1 
ATOM   8268  C  C   . PRO B 1 181 ? 130.798 124.024 186.765 1.00 91.49  ? 181  PRO B C   1 
ATOM   8269  O  O   . PRO B 1 181 ? 131.371 123.310 185.939 1.00 91.49  ? 181  PRO B O   1 
ATOM   8270  C  CB  . PRO B 1 181 ? 128.680 125.053 185.861 1.00 91.49  ? 181  PRO B CB  1 
ATOM   8271  C  CG  . PRO B 1 181 ? 128.483 126.032 184.764 1.00 91.49  ? 181  PRO B CG  1 
ATOM   8272  C  CD  . PRO B 1 181 ? 129.819 126.153 184.092 1.00 91.49  ? 181  PRO B CD  1 
ATOM   8273  N  N   . GLY B 1 182 ? 130.735 123.730 188.058 1.00 98.71  ? 182  GLY B N   1 
ATOM   8274  C  CA  . GLY B 1 182 ? 131.434 122.578 188.595 1.00 98.71  ? 182  GLY B CA  1 
ATOM   8275  C  C   . GLY B 1 182 ? 132.940 122.716 188.569 1.00 98.71  ? 182  GLY B C   1 
ATOM   8276  O  O   . GLY B 1 182 ? 133.642 121.749 188.248 1.00 98.71  ? 182  GLY B O   1 
ATOM   8277  N  N   . ASP B 1 183 ? 133.454 123.898 188.889 1.00 92.70  ? 183  ASP B N   1 
ATOM   8278  C  CA  . ASP B 1 183 ? 134.884 124.148 188.943 1.00 92.70  ? 183  ASP B CA  1 
ATOM   8279  C  C   . ASP B 1 183 ? 135.283 124.481 190.375 1.00 92.70  ? 183  ASP B C   1 
ATOM   8280  O  O   . ASP B 1 183 ? 134.609 125.254 191.061 1.00 92.70  ? 183  ASP B O   1 
ATOM   8281  C  CB  . ASP B 1 183 ? 135.277 125.291 188.000 1.00 92.70  ? 183  ASP B CB  1 
ATOM   8282  C  CG  . ASP B 1 183 ? 136.780 125.451 187.860 1.00 92.70  ? 183  ASP B CG  1 
ATOM   8283  O  OD1 . ASP B 1 183 ? 137.535 124.701 188.515 1.00 92.70  ? 183  ASP B OD1 1 
ATOM   8284  O  OD2 . ASP B 1 183 ? 137.209 126.330 187.084 1.00 92.70  ? 183  ASP B OD2 1 
ATOM   8285  N  N   . ILE B 1 184 ? 136.384 123.887 190.822 1.00 86.43  ? 184  ILE B N   1 
ATOM   8286  C  CA  . ILE B 1 184 ? 136.853 124.028 192.195 1.00 86.43  ? 184  ILE B CA  1 
ATOM   8287  C  C   . ILE B 1 184 ? 137.822 125.199 192.255 1.00 86.43  ? 184  ILE B C   1 
ATOM   8288  O  O   . ILE B 1 184 ? 138.819 125.230 191.522 1.00 86.43  ? 184  ILE B O   1 
ATOM   8289  C  CB  . ILE B 1 184 ? 137.514 122.736 192.698 1.00 86.43  ? 184  ILE B CB  1 
ATOM   8290  C  CG1 . ILE B 1 184 ? 136.529 121.569 192.617 1.00 86.43  ? 184  ILE B CG1 1 
ATOM   8291  C  CG2 . ILE B 1 184 ? 138.017 122.916 194.120 1.00 86.43  ? 184  ILE B CG2 1 
ATOM   8292  C  CD1 . ILE B 1 184 ? 137.153 120.224 192.913 1.00 86.43  ? 184  ILE B CD1 1 
ATOM   8293  N  N   . ILE B 1 185 ? 137.529 126.165 193.125 1.00 77.03  ? 185  ILE B N   1 
ATOM   8294  C  CA  . ILE B 1 185 ? 138.373 127.333 193.328 1.00 77.03  ? 185  ILE B CA  1 
ATOM   8295  C  C   . ILE B 1 185 ? 138.660 127.468 194.817 1.00 77.03  ? 185  ILE B C   1 
ATOM   8296  O  O   . ILE B 1 185 ? 138.012 126.846 195.659 1.00 77.03  ? 185  ILE B O   1 
ATOM   8297  C  CB  . ILE B 1 185 ? 137.733 128.629 192.786 1.00 77.03  ? 185  ILE B CB  1 
ATOM   8298  C  CG1 . ILE B 1 185 ? 136.576 129.070 193.681 1.00 77.03  ? 185  ILE B CG1 1 
ATOM   8299  C  CG2 . ILE B 1 185 ? 137.245 128.436 191.364 1.00 77.03  ? 185  ILE B CG2 1 
ATOM   8300  C  CD1 . ILE B 1 185 ? 135.941 130.369 193.247 1.00 77.03  ? 185  ILE B CD1 1 
ATOM   8301  N  N   . LYS B 1 186 ? 139.657 128.292 195.133 1.00 75.26  ? 186  LYS B N   1 
ATOM   8302  C  CA  . LYS B 1 186 ? 139.994 128.607 196.513 1.00 75.26  ? 186  LYS B CA  1 
ATOM   8303  C  C   . LYS B 1 186 ? 139.864 130.108 196.727 1.00 75.26  ? 186  LYS B C   1 
ATOM   8304  O  O   . LYS B 1 186 ? 140.147 130.904 195.827 1.00 75.26  ? 186  LYS B O   1 
ATOM   8305  C  CB  . LYS B 1 186 ? 141.408 128.129 196.883 1.00 75.26  ? 186  LYS B CB  1 
ATOM   8306  C  CG  . LYS B 1 186 ? 142.543 128.977 196.342 1.00 75.26  ? 186  LYS B CG  1 
ATOM   8307  C  CD  . LYS B 1 186 ? 143.835 128.681 197.087 1.00 75.26  ? 186  LYS B CD  1 
ATOM   8308  C  CE  . LYS B 1 186 ? 145.022 129.376 196.441 1.00 75.26  ? 186  LYS B CE  1 
ATOM   8309  N  NZ  . LYS B 1 186 ? 146.315 128.893 196.997 1.00 75.26  ? 186  LYS B NZ  1 
ATOM   8310  N  N   . LEU B 1 187 ? 139.418 130.481 197.921 1.00 65.96  ? 187  LEU B N   1 
ATOM   8311  C  CA  . LEU B 1 187 ? 139.118 131.858 198.275 1.00 65.96  ? 187  LEU B CA  1 
ATOM   8312  C  C   . LEU B 1 187 ? 139.976 132.280 199.456 1.00 65.96  ? 187  LEU B C   1 
ATOM   8313  O  O   . LEU B 1 187 ? 140.080 131.554 200.451 1.00 65.96  ? 187  LEU B O   1 
ATOM   8314  C  CB  . LEU B 1 187 ? 137.639 132.016 198.633 1.00 65.96  ? 187  LEU B CB  1 
ATOM   8315  C  CG  . LEU B 1 187 ? 136.623 131.680 197.544 1.00 65.96  ? 187  LEU B CG  1 
ATOM   8316  C  CD1 . LEU B 1 187 ? 135.222 131.723 198.119 1.00 65.96  ? 187  LEU B CD1 1 
ATOM   8317  C  CD2 . LEU B 1 187 ? 136.755 132.636 196.371 1.00 65.96  ? 187  LEU B CD2 1 
ATOM   8318  N  N   . ALA B 1 188 ? 140.581 133.460 199.342 1.00 62.58  ? 188  ALA B N   1 
ATOM   8319  C  CA  . ALA B 1 188 ? 141.386 134.052 200.398 1.00 62.58  ? 188  ALA B CA  1 
ATOM   8320  C  C   . ALA B 1 188 ? 140.847 135.443 200.707 1.00 62.58  ? 188  ALA B C   1 
ATOM   8321  O  O   . ALA B 1 188 ? 139.833 135.878 200.153 1.00 62.58  ? 188  ALA B O   1 
ATOM   8322  C  CB  . ALA B 1 188 ? 142.867 134.109 200.001 1.00 62.58  ? 188  ALA B CB  1 
ATOM   8323  N  N   . ALA B 1 189 ? 141.536 136.146 201.601 1.00 58.76  ? 189  ALA B N   1 
ATOM   8324  C  CA  . ALA B 1 189 ? 141.102 137.477 202.000 1.00 58.76  ? 189  ALA B CA  1 
ATOM   8325  C  C   . ALA B 1 189 ? 141.234 138.460 200.844 1.00 58.76  ? 189  ALA B C   1 
ATOM   8326  O  O   . ALA B 1 189 ? 142.257 138.503 200.155 1.00 58.76  ? 189  ALA B O   1 
ATOM   8327  C  CB  . ALA B 1 189 ? 141.916 137.965 203.196 1.00 58.76  ? 189  ALA B CB  1 
ATOM   8328  N  N   . GLY B 1 190 ? 140.188 139.255 200.635 1.00 57.36  ? 190  GLY B N   1 
ATOM   8329  C  CA  . GLY B 1 190 ? 140.196 140.284 199.619 1.00 57.36  ? 190  GLY B CA  1 
ATOM   8330  C  C   . GLY B 1 190 ? 139.764 139.846 198.238 1.00 57.36  ? 190  GLY B C   1 
ATOM   8331  O  O   . GLY B 1 190 ? 139.635 140.699 197.350 1.00 57.36  ? 190  GLY B O   1 
ATOM   8332  N  N   . ASP B 1 191 ? 139.534 138.554 198.021 1.00 60.20  ? 191  ASP B N   1 
ATOM   8333  C  CA  . ASP B 1 191 ? 139.106 138.054 196.722 1.00 60.20  ? 191  ASP B CA  1 
ATOM   8334  C  C   . ASP B 1 191 ? 137.585 138.044 196.649 1.00 60.20  ? 191  ASP B C   1 
ATOM   8335  O  O   . ASP B 1 191 ? 136.920 137.447 197.501 1.00 60.20  ? 191  ASP B O   1 
ATOM   8336  C  CB  . ASP B 1 191 ? 139.656 136.649 196.475 1.00 60.20  ? 191  ASP B CB  1 
ATOM   8337  C  CG  . ASP B 1 191 ? 141.165 136.629 196.332 1.00 60.20  ? 191  ASP B CG  1 
ATOM   8338  O  OD1 . ASP B 1 191 ? 141.734 137.637 195.862 1.00 60.20  ? 191  ASP B OD1 1 
ATOM   8339  O  OD2 . ASP B 1 191 ? 141.784 135.604 196.687 1.00 60.20  ? 191  ASP B OD2 1 
ATOM   8340  N  N   . MET B 1 192 ? 137.039 138.705 195.632 1.00 62.31  ? 192  MET B N   1 
ATOM   8341  C  CA  . MET B 1 192 ? 135.597 138.735 195.449 1.00 62.31  ? 192  MET B CA  1 
ATOM   8342  C  C   . MET B 1 192 ? 135.096 137.388 194.947 1.00 62.31  ? 192  MET B C   1 
ATOM   8343  O  O   . MET B 1 192 ? 135.844 136.596 194.366 1.00 62.31  ? 192  MET B O   1 
ATOM   8344  C  CB  . MET B 1 192 ? 135.190 139.832 194.465 1.00 62.31  ? 192  MET B CB  1 
ATOM   8345  C  CG  . MET B 1 192 ? 135.304 139.429 193.003 1.00 62.31  ? 192  MET B CG  1 
ATOM   8346  S  SD  . MET B 1 192 ? 134.686 140.692 191.875 1.00 62.31  ? 192  MET B SD  1 
ATOM   8347  C  CE  . MET B 1 192 ? 132.930 140.623 192.221 1.00 62.31  ? 192  MET B CE  1 
ATOM   8348  N  N   . ILE B 1 193 ? 133.813 137.132 195.180 1.00 68.77  ? 193  ILE B N   1 
ATOM   8349  C  CA  . ILE B 1 193 ? 133.178 135.901 194.723 1.00 68.77  ? 193  ILE B CA  1 
ATOM   8350  C  C   . ILE B 1 193 ? 132.912 136.028 193.228 1.00 68.77  ? 193  ILE B C   1 
ATOM   8351  O  O   . ILE B 1 193 ? 132.184 136.937 192.804 1.00 68.77  ? 193  ILE B O   1 
ATOM   8352  C  CB  . ILE B 1 193 ? 131.889 135.619 195.506 1.00 68.77  ? 193  ILE B CB  1 
ATOM   8353  C  CG1 . ILE B 1 193 ? 132.169 135.634 197.008 1.00 68.77  ? 193  ILE B CG1 1 
ATOM   8354  C  CG2 . ILE B 1 193 ? 131.305 134.288 195.101 1.00 68.77  ? 193  ILE B CG2 1 
ATOM   8355  C  CD1 . ILE B 1 193 ? 133.213 134.640 197.436 1.00 68.77  ? 193  ILE B CD1 1 
ATOM   8356  N  N   . PRO B 1 194 ? 133.468 135.149 192.396 1.00 70.88  ? 194  PRO B N   1 
ATOM   8357  C  CA  . PRO B 1 194 ? 133.336 135.323 190.943 1.00 70.88  ? 194  PRO B CA  1 
ATOM   8358  C  C   . PRO B 1 194 ? 132.021 134.794 190.393 1.00 70.88  ? 194  PRO B C   1 
ATOM   8359  O  O   . PRO B 1 194 ? 131.544 135.262 189.354 1.00 70.88  ? 194  PRO B O   1 
ATOM   8360  C  CB  . PRO B 1 194 ? 134.532 134.540 190.381 1.00 70.88  ? 194  PRO B CB  1 
ATOM   8361  C  CG  . PRO B 1 194 ? 135.185 133.844 191.559 1.00 70.88  ? 194  PRO B CG  1 
ATOM   8362  C  CD  . PRO B 1 194 ? 134.290 133.981 192.743 1.00 70.88  ? 194  PRO B CD  1 
ATOM   8363  N  N   . ALA B 1 195 ? 131.427 133.822 191.079 1.00 77.74  ? 195  ALA B N   1 
ATOM   8364  C  CA  . ALA B 1 195 ? 130.177 133.218 190.640 1.00 77.74  ? 195  ALA B CA  1 
ATOM   8365  C  C   . ALA B 1 195 ? 129.563 132.485 191.822 1.00 77.74  ? 195  ALA B C   1 
ATOM   8366  O  O   . ALA B 1 195 ? 130.152 132.409 192.901 1.00 77.74  ? 195  ALA B O   1 
ATOM   8367  C  CB  . ALA B 1 195 ? 130.396 132.272 189.456 1.00 77.74  ? 195  ALA B CB  1 
ATOM   8368  N  N   . ASP B 1 196 ? 128.364 131.947 191.606 1.00 88.44  ? 196  ASP B N   1 
ATOM   8369  C  CA  . ASP B 1 196 ? 127.693 131.189 192.653 1.00 88.44  ? 196  ASP B CA  1 
ATOM   8370  C  C   . ASP B 1 196 ? 128.553 130.004 193.074 1.00 88.44  ? 196  ASP B C   1 
ATOM   8371  O  O   . ASP B 1 196 ? 129.039 129.243 192.232 1.00 88.44  ? 196  ASP B O   1 
ATOM   8372  C  CB  . ASP B 1 196 ? 126.326 130.712 192.165 1.00 88.44  ? 196  ASP B CB  1 
ATOM   8373  C  CG  . ASP B 1 196 ? 125.311 131.833 192.096 1.00 88.44  ? 196  ASP B CG  1 
ATOM   8374  O  OD1 . ASP B 1 196 ? 125.474 132.828 192.832 1.00 88.44  ? 196  ASP B OD1 1 
ATOM   8375  O  OD2 . ASP B 1 196 ? 124.352 131.723 191.303 1.00 88.44  ? 196  ASP B OD2 1 
ATOM   8376  N  N   . LEU B 1 197 ? 128.738 129.847 194.382 1.00 84.68  ? 197  LEU B N   1 
ATOM   8377  C  CA  . LEU B 1 197 ? 129.678 128.877 194.919 1.00 84.68  ? 197  LEU B CA  1 
ATOM   8378  C  C   . LEU B 1 197 ? 129.011 128.016 195.980 1.00 84.68  ? 197  LEU B C   1 
ATOM   8379  O  O   . LEU B 1 197 ? 128.158 128.482 196.738 1.00 84.68  ? 197  LEU B O   1 
ATOM   8380  C  CB  . LEU B 1 197 ? 130.904 129.568 195.529 1.00 84.68  ? 197  LEU B CB  1 
ATOM   8381  C  CG  . LEU B 1 197 ? 131.865 130.254 194.560 1.00 84.68  ? 197  LEU B CG  1 
ATOM   8382  C  CD1 . LEU B 1 197 ? 133.001 130.907 195.322 1.00 84.68  ? 197  LEU B CD1 1 
ATOM   8383  C  CD2 . LEU B 1 197 ? 132.401 129.260 193.550 1.00 84.68  ? 197  LEU B CD2 1 
ATOM   8384  N  N   . ARG B 1 198 ? 129.415 126.748 196.022 1.00 93.44  ? 198  ARG B N   1 
ATOM   8385  C  CA  . ARG B 1 198 ? 129.057 125.832 197.097 1.00 93.44  ? 198  ARG B CA  1 
ATOM   8386  C  C   . ARG B 1 198 ? 130.314 125.561 197.907 1.00 93.44  ? 198  ARG B C   1 
ATOM   8387  O  O   . ARG B 1 198 ? 131.296 125.035 197.373 1.00 93.44  ? 198  ARG B O   1 
ATOM   8388  C  CB  . ARG B 1 198 ? 128.473 124.529 196.547 1.00 93.44  ? 198  ARG B CB  1 
ATOM   8389  C  CG  . ARG B 1 198 ? 128.252 123.451 197.596 1.00 93.44  ? 198  ARG B CG  1 
ATOM   8390  C  CD  . ARG B 1 198 ? 127.021 123.743 198.437 1.00 93.44  ? 198  ARG B CD  1 
ATOM   8391  N  NE  . ARG B 1 198 ? 126.672 122.621 199.300 1.00 93.44  ? 198  ARG B NE  1 
ATOM   8392  C  CZ  . ARG B 1 198 ? 127.270 122.348 200.451 1.00 93.44  ? 198  ARG B CZ  1 
ATOM   8393  N  NH1 . ARG B 1 198 ? 128.252 123.103 200.916 1.00 93.44  ? 198  ARG B NH1 1 
ATOM   8394  N  NH2 . ARG B 1 198 ? 126.872 121.292 201.154 1.00 93.44  ? 198  ARG B NH2 1 
ATOM   8395  N  N   . ILE B 1 199 ? 130.283 125.913 199.190 1.00 88.95  ? 199  ILE B N   1 
ATOM   8396  C  CA  . ILE B 1 199 ? 131.487 125.853 200.010 1.00 88.95  ? 199  ILE B CA  1 
ATOM   8397  C  C   . ILE B 1 199 ? 131.802 124.399 200.338 1.00 88.95  ? 199  ILE B C   1 
ATOM   8398  O  O   . ILE B 1 199 ? 131.029 123.719 201.022 1.00 88.95  ? 199  ILE B O   1 
ATOM   8399  C  CB  . ILE B 1 199 ? 131.322 126.686 201.287 1.00 88.95  ? 199  ILE B CB  1 
ATOM   8400  C  CG1 . ILE B 1 199 ? 131.169 128.167 200.940 1.00 88.95  ? 199  ILE B CG1 1 
ATOM   8401  C  CG2 . ILE B 1 199 ? 132.509 126.478 202.211 1.00 88.95  ? 199  ILE B CG2 1 
ATOM   8402  C  CD1 . ILE B 1 199 ? 132.434 128.800 200.407 1.00 88.95  ? 199  ILE B CD1 1 
ATOM   8403  N  N   . LEU B 1 200 ? 132.945 123.917 199.848 1.00 87.53  ? 200  LEU B N   1 
ATOM   8404  C  CA  . LEU B 1 200 ? 133.393 122.572 200.193 1.00 87.53  ? 200  LEU B CA  1 
ATOM   8405  C  C   . LEU B 1 200 ? 134.063 122.553 201.561 1.00 87.53  ? 200  LEU B C   1 
ATOM   8406  O  O   . LEU B 1 200 ? 133.798 121.664 202.378 1.00 87.53  ? 200  LEU B O   1 
ATOM   8407  C  CB  . LEU B 1 200 ? 134.344 122.041 199.120 1.00 87.53  ? 200  LEU B CB  1 
ATOM   8408  C  CG  . LEU B 1 200 ? 133.772 121.933 197.706 1.00 87.53  ? 200  LEU B CG  1 
ATOM   8409  C  CD1 . LEU B 1 200 ? 134.707 121.139 196.809 1.00 87.53  ? 200  LEU B CD1 1 
ATOM   8410  C  CD2 . LEU B 1 200 ? 132.393 121.298 197.738 1.00 87.53  ? 200  LEU B CD2 1 
ATOM   8411  N  N   . GLN B 1 201 ? 134.935 123.523 201.825 1.00 84.28  ? 201  GLN B N   1 
ATOM   8412  C  CA  . GLN B 1 201 ? 135.554 123.657 203.136 1.00 84.28  ? 201  GLN B CA  1 
ATOM   8413  C  C   . GLN B 1 201 ? 135.802 125.130 203.414 1.00 84.28  ? 201  GLN B C   1 
ATOM   8414  O  O   . GLN B 1 201 ? 135.994 125.925 202.491 1.00 84.28  ? 201  GLN B O   1 
ATOM   8415  C  CB  . GLN B 1 201 ? 136.863 122.864 203.231 1.00 84.28  ? 201  GLN B CB  1 
ATOM   8416  C  CG  . GLN B 1 201 ? 137.834 123.131 202.097 1.00 84.28  ? 201  GLN B CG  1 
ATOM   8417  C  CD  . GLN B 1 201 ? 139.256 122.741 202.445 1.00 84.28  ? 201  GLN B CD  1 
ATOM   8418  O  OE1 . GLN B 1 201 ? 139.815 123.208 203.438 1.00 84.28  ? 201  GLN B OE1 1 
ATOM   8419  N  NE2 . GLN B 1 201 ? 139.851 121.880 201.628 1.00 84.28  ? 201  GLN B NE2 1 
ATOM   8420  N  N   . ALA B 1 202 ? 135.808 125.487 204.697 1.00 81.13  ? 202  ALA B N   1 
ATOM   8421  C  CA  . ALA B 1 202 ? 135.957 126.881 205.094 1.00 81.13  ? 202  ALA B CA  1 
ATOM   8422  C  C   . ALA B 1 202 ? 136.648 126.962 206.445 1.00 81.13  ? 202  ALA B C   1 
ATOM   8423  O  O   . ALA B 1 202 ? 136.275 126.250 207.381 1.00 81.13  ? 202  ALA B O   1 
ATOM   8424  C  CB  . ALA B 1 202 ? 134.597 127.584 205.154 1.00 81.13  ? 202  ALA B CB  1 
ATOM   8425  N  N   . ARG B 1 203 ? 137.652 127.830 206.536 1.00 78.76  ? 203  ARG B N   1 
ATOM   8426  C  CA  . ARG B 1 203 ? 138.370 128.121 207.771 1.00 78.76  ? 203  ARG B CA  1 
ATOM   8427  C  C   . ARG B 1 203 ? 138.126 129.590 208.103 1.00 78.76  ? 203  ARG B C   1 
ATOM   8428  O  O   . ARG B 1 203 ? 138.739 130.482 207.504 1.00 78.76  ? 203  ARG B O   1 
ATOM   8429  C  CB  . ARG B 1 203 ? 139.857 127.815 207.619 1.00 78.76  ? 203  ARG B CB  1 
ATOM   8430  C  CG  . ARG B 1 203 ? 140.667 127.967 208.895 1.00 78.76  ? 203  ARG B CG  1 
ATOM   8431  C  CD  . ARG B 1 203 ? 140.331 126.883 209.904 1.00 78.76  ? 203  ARG B CD  1 
ATOM   8432  N  NE  . ARG B 1 203 ? 141.067 127.058 211.151 1.00 78.76  ? 203  ARG B NE  1 
ATOM   8433  C  CZ  . ARG B 1 203 ? 140.666 127.825 212.155 1.00 78.76  ? 203  ARG B CZ  1 
ATOM   8434  N  NH1 . ARG B 1 203 ? 139.534 128.506 212.096 1.00 78.76  ? 203  ARG B NH1 1 
ATOM   8435  N  NH2 . ARG B 1 203 ? 141.421 127.912 213.247 1.00 78.76  ? 203  ARG B NH2 1 
ATOM   8436  N  N   . ASP B 1 204 ? 137.211 129.827 209.046 1.00 71.98  ? 204  ASP B N   1 
ATOM   8437  C  CA  . ASP B 1 204 ? 136.887 131.164 209.548 1.00 71.98  ? 204  ASP B CA  1 
ATOM   8438  C  C   . ASP B 1 204 ? 136.538 132.121 208.411 1.00 71.98  ? 204  ASP B C   1 
ATOM   8439  O  O   . ASP B 1 204 ? 136.975 133.274 208.376 1.00 71.98  ? 204  ASP B O   1 
ATOM   8440  C  CB  . ASP B 1 204 ? 138.031 131.718 210.398 1.00 71.98  ? 204  ASP B CB  1 
ATOM   8441  C  CG  . ASP B 1 204 ? 137.938 131.288 211.848 1.00 71.98  ? 204  ASP B CG  1 
ATOM   8442  O  OD1 . ASP B 1 204 ? 136.856 131.451 212.449 1.00 71.98  ? 204  ASP B OD1 1 
ATOM   8443  O  OD2 . ASP B 1 204 ? 138.947 130.790 212.387 1.00 71.98  ? 204  ASP B OD2 1 
ATOM   8444  N  N   . LEU B 1 205 ? 135.728 131.636 207.475 1.00 70.19  ? 205  LEU B N   1 
ATOM   8445  C  CA  . LEU B 1 205 ? 135.383 132.416 206.294 1.00 70.19  ? 205  LEU B CA  1 
ATOM   8446  C  C   . LEU B 1 205 ? 134.298 133.430 206.637 1.00 70.19  ? 205  LEU B C   1 
ATOM   8447  O  O   . LEU B 1 205 ? 133.151 133.056 206.907 1.00 70.19  ? 205  LEU B O   1 
ATOM   8448  C  CB  . LEU B 1 205 ? 134.924 131.501 205.163 1.00 70.19  ? 205  LEU B CB  1 
ATOM   8449  C  CG  . LEU B 1 205 ? 134.739 132.198 203.815 1.00 70.19  ? 205  LEU B CG  1 
ATOM   8450  C  CD1 . LEU B 1 205 ? 136.092 132.500 203.198 1.00 70.19  ? 205  LEU B CD1 1 
ATOM   8451  C  CD2 . LEU B 1 205 ? 133.897 131.357 202.874 1.00 70.19  ? 205  LEU B CD2 1 
ATOM   8452  N  N   . PHE B 1 206 ? 134.664 134.709 206.630 1.00 64.06  ? 206  PHE B N   1 
ATOM   8453  C  CA  . PHE B 1 206 ? 133.732 135.815 206.796 1.00 64.06  ? 206  PHE B CA  1 
ATOM   8454  C  C   . PHE B 1 206 ? 133.705 136.613 205.503 1.00 64.06  ? 206  PHE B C   1 
ATOM   8455  O  O   . PHE B 1 206 ? 134.756 137.054 205.024 1.00 64.06  ? 206  PHE B O   1 
ATOM   8456  C  CB  . PHE B 1 206 ? 134.137 136.722 207.961 1.00 64.06  ? 206  PHE B CB  1 
ATOM   8457  C  CG  . PHE B 1 206 ? 133.823 136.157 209.316 1.00 64.06  ? 206  PHE B CG  1 
ATOM   8458  C  CD1 . PHE B 1 206 ? 134.705 135.295 209.943 1.00 64.06  ? 206  PHE B CD1 1 
ATOM   8459  C  CD2 . PHE B 1 206 ? 132.651 136.500 209.967 1.00 64.06  ? 206  PHE B CD2 1 
ATOM   8460  C  CE1 . PHE B 1 206 ? 134.422 134.782 211.193 1.00 64.06  ? 206  PHE B CE1 1 
ATOM   8461  C  CE2 . PHE B 1 206 ? 132.361 135.988 211.216 1.00 64.06  ? 206  PHE B CE2 1 
ATOM   8462  C  CZ  . PHE B 1 206 ? 133.247 135.128 211.829 1.00 64.06  ? 206  PHE B CZ  1 
ATOM   8463  N  N   . VAL B 1 207 ? 132.508 136.804 204.951 1.00 63.64  ? 207  VAL B N   1 
ATOM   8464  C  CA  . VAL B 1 207 ? 132.321 137.470 203.667 1.00 63.64  ? 207  VAL B CA  1 
ATOM   8465  C  C   . VAL B 1 207 ? 131.413 138.676 203.858 1.00 63.64  ? 207  VAL B C   1 
ATOM   8466  O  O   . VAL B 1 207 ? 130.586 138.704 204.774 1.00 63.64  ? 207  VAL B O   1 
ATOM   8467  C  CB  . VAL B 1 207 ? 131.738 136.512 202.607 1.00 63.64  ? 207  VAL B CB  1 
ATOM   8468  C  CG1 . VAL B 1 207 ? 132.656 135.317 202.408 1.00 63.64  ? 207  VAL B CG1 1 
ATOM   8469  C  CG2 . VAL B 1 207 ? 130.344 136.058 203.007 1.00 63.64  ? 207  VAL B CG2 1 
ATOM   8470  N  N   . ALA B 1 208 ? 131.571 139.675 202.991 1.00 64.46  ? 208  ALA B N   1 
ATOM   8471  C  CA  . ALA B 1 208 ? 130.778 140.902 203.043 1.00 64.46  ? 208  ALA B CA  1 
ATOM   8472  C  C   . ALA B 1 208 ? 129.671 140.807 202.000 1.00 64.46  ? 208  ALA B C   1 
ATOM   8473  O  O   . ALA B 1 208 ? 129.930 140.864 200.796 1.00 64.46  ? 208  ALA B O   1 
ATOM   8474  C  CB  . ALA B 1 208 ? 131.656 142.126 202.810 1.00 64.46  ? 208  ALA B CB  1 
ATOM   8475  N  N   . GLN B 1 209 ? 128.429 140.665 202.466 1.00 72.97  ? 209  GLN B N   1 
ATOM   8476  C  CA  . GLN B 1 209 ? 127.266 140.596 201.592 1.00 72.97  ? 209  GLN B CA  1 
ATOM   8477  C  C   . GLN B 1 209 ? 126.425 141.867 201.643 1.00 72.97  ? 209  GLN B C   1 
ATOM   8478  O  O   . GLN B 1 209 ? 125.227 141.829 201.344 1.00 72.97  ? 209  GLN B O   1 
ATOM   8479  C  CB  . GLN B 1 209 ? 126.407 139.380 201.937 1.00 72.97  ? 209  GLN B CB  1 
ATOM   8480  C  CG  . GLN B 1 209 ? 126.933 138.072 201.372 1.00 72.97  ? 209  GLN B CG  1 
ATOM   8481  C  CD  . GLN B 1 209 ? 126.183 136.865 201.897 1.00 72.97  ? 209  GLN B CD  1 
ATOM   8482  O  OE1 . GLN B 1 209 ? 125.488 136.943 202.911 1.00 72.97  ? 209  GLN B OE1 1 
ATOM   8483  N  NE2 . GLN B 1 209 ? 126.311 135.743 201.201 1.00 72.97  ? 209  GLN B NE2 1 
ATOM   8484  N  N   . ALA B 1 210 ? 127.032 142.997 202.014 1.00 79.74  ? 210  ALA B N   1 
ATOM   8485  C  CA  . ALA B 1 210 ? 126.287 144.251 202.072 1.00 79.74  ? 210  ALA B CA  1 
ATOM   8486  C  C   . ALA B 1 210 ? 125.769 144.661 200.700 1.00 79.74  ? 210  ALA B C   1 
ATOM   8487  O  O   . ALA B 1 210 ? 124.803 145.426 200.604 1.00 79.74  ? 210  ALA B O   1 
ATOM   8488  C  CB  . ALA B 1 210 ? 127.163 145.356 202.661 1.00 79.74  ? 210  ALA B CB  1 
ATOM   8489  N  N   . SER B 1 211 ? 126.401 144.172 199.632 1.00 80.46  ? 211  SER B N   1 
ATOM   8490  C  CA  . SER B 1 211 ? 125.940 144.493 198.286 1.00 80.46  ? 211  SER B CA  1 
ATOM   8491  C  C   . SER B 1 211 ? 124.566 143.895 198.008 1.00 80.46  ? 211  SER B C   1 
ATOM   8492  O  O   . SER B 1 211 ? 123.703 144.558 197.420 1.00 80.46  ? 211  SER B O   1 
ATOM   8493  C  CB  . SER B 1 211 ? 126.957 144.000 197.259 1.00 80.46  ? 211  SER B CB  1 
ATOM   8494  O  OG  . SER B 1 211 ? 127.034 142.586 197.257 1.00 80.46  ? 211  SER B OG  1 
ATOM   8495  N  N   . LEU B 1 212 ? 124.343 142.647 198.420 1.00 81.64  ? 212  LEU B N   1 
ATOM   8496  C  CA  . LEU B 1 212 ? 123.099 141.962 198.079 1.00 81.64  ? 212  LEU B CA  1 
ATOM   8497  C  C   . LEU B 1 212 ? 122.062 142.086 199.191 1.00 81.64  ? 212  LEU B C   1 
ATOM   8498  O  O   . LEU B 1 212 ? 120.968 142.620 198.977 1.00 81.64  ? 212  LEU B O   1 
ATOM   8499  C  CB  . LEU B 1 212 ? 123.385 140.491 197.768 1.00 81.64  ? 212  LEU B CB  1 
ATOM   8500  C  CG  . LEU B 1 212 ? 124.293 140.233 196.564 1.00 81.64  ? 212  LEU B CG  1 
ATOM   8501  C  CD1 . LEU B 1 212 ? 124.274 138.764 196.186 1.00 81.64  ? 212  LEU B CD1 1 
ATOM   8502  C  CD2 . LEU B 1 212 ? 123.879 141.098 195.382 1.00 81.64  ? 212  LEU B CD2 1 
ATOM   8503  N  N   . THR B 1 213 ? 122.387 141.597 200.388 1.00 86.90  ? 213  THR B N   1 
ATOM   8504  C  CA  . THR B 1 213 ? 121.423 141.588 201.481 1.00 86.90  ? 213  THR B CA  1 
ATOM   8505  C  C   . THR B 1 213 ? 121.319 142.927 202.200 1.00 86.90  ? 213  THR B C   1 
ATOM   8506  O  O   . THR B 1 213 ? 120.381 143.118 202.982 1.00 86.90  ? 213  THR B O   1 
ATOM   8507  C  CB  . THR B 1 213 ? 121.773 140.492 202.493 1.00 86.90  ? 213  THR B CB  1 
ATOM   8508  O  OG1 . THR B 1 213 ? 120.642 140.240 203.336 1.00 86.90  ? 213  THR B OG1 1 
ATOM   8509  C  CG2 . THR B 1 213 ? 122.950 140.913 203.357 1.00 86.90  ? 213  THR B CG2 1 
ATOM   8510  N  N   . GLY B 1 214 ? 122.246 143.851 201.962 1.00 85.26  ? 214  GLY B N   1 
ATOM   8511  C  CA  . GLY B 1 214 ? 122.182 145.158 202.580 1.00 85.26  ? 214  GLY B CA  1 
ATOM   8512  C  C   . GLY B 1 214 ? 122.678 145.229 204.005 1.00 85.26  ? 214  GLY B C   1 
ATOM   8513  O  O   . GLY B 1 214 ? 122.511 146.271 204.649 1.00 85.26  ? 214  GLY B O   1 
ATOM   8514  N  N   . GLU B 1 215 ? 123.281 144.162 204.522 1.00 89.55  ? 215  GLU B N   1 
ATOM   8515  C  CA  . GLU B 1 215 ? 123.803 144.132 205.882 1.00 89.55  ? 215  GLU B CA  1 
ATOM   8516  C  C   . GLU B 1 215 ? 125.307 144.366 205.850 1.00 89.55  ? 215  GLU B C   1 
ATOM   8517  O  O   . GLU B 1 215 ? 126.046 143.599 205.223 1.00 89.55  ? 215  GLU B O   1 
ATOM   8518  C  CB  . GLU B 1 215 ? 123.485 142.799 206.562 1.00 89.55  ? 215  GLU B CB  1 
ATOM   8519  C  CG  . GLU B 1 215 ? 121.998 142.512 206.689 1.00 89.55  ? 215  GLU B CG  1 
ATOM   8520  C  CD  . GLU B 1 215 ? 121.707 141.341 207.606 1.00 89.55  ? 215  GLU B CD  1 
ATOM   8521  O  OE1 . GLU B 1 215 ? 122.365 140.290 207.458 1.00 89.55  ? 215  GLU B OE1 1 
ATOM   8522  O  OE2 . GLU B 1 215 ? 120.820 141.471 208.476 1.00 89.55  ? 215  GLU B OE2 1 
ATOM   8523  N  N   . SER B 1 216 ? 125.755 145.419 206.536 1.00 83.12  ? 216  SER B N   1 
ATOM   8524  C  CA  . SER B 1 216 ? 127.160 145.807 206.490 1.00 83.12  ? 216  SER B CA  1 
ATOM   8525  C  C   . SER B 1 216 ? 128.071 144.789 207.165 1.00 83.12  ? 216  SER B C   1 
ATOM   8526  O  O   . SER B 1 216 ? 129.193 144.568 206.698 1.00 83.12  ? 216  SER B O   1 
ATOM   8527  C  CB  . SER B 1 216 ? 127.346 147.181 207.139 1.00 83.12  ? 216  SER B CB  1 
ATOM   8528  O  OG  . SER B 1 216 ? 126.720 148.195 206.373 1.00 83.12  ? 216  SER B OG  1 
ATOM   8529  N  N   . LEU B 1 217 ? 127.620 144.175 208.251 1.00 72.91  ? 217  LEU B N   1 
ATOM   8530  C  CA  . LEU B 1 217 ? 128.466 143.243 208.988 1.00 72.91  ? 217  LEU B CA  1 
ATOM   8531  C  C   . LEU B 1 217 ? 128.760 142.010 208.141 1.00 72.91  ? 217  LEU B C   1 
ATOM   8532  O  O   . LEU B 1 217 ? 127.857 141.492 207.474 1.00 72.91  ? 217  LEU B O   1 
ATOM   8533  C  CB  . LEU B 1 217 ? 127.800 142.829 210.297 1.00 72.91  ? 217  LEU B CB  1 
ATOM   8534  C  CG  . LEU B 1 217 ? 127.961 143.759 211.500 1.00 72.91  ? 217  LEU B CG  1 
ATOM   8535  C  CD1 . LEU B 1 217 ? 127.064 144.977 211.369 1.00 72.91  ? 217  LEU B CD1 1 
ATOM   8536  C  CD2 . LEU B 1 217 ? 127.668 143.011 212.791 1.00 72.91  ? 217  LEU B CD2 1 
ATOM   8537  N  N   . PRO B 1 218 ? 129.997 141.519 208.131 1.00 64.10  ? 218  PRO B N   1 
ATOM   8538  C  CA  . PRO B 1 218 ? 130.285 140.268 207.426 1.00 64.10  ? 218  PRO B CA  1 
ATOM   8539  C  C   . PRO B 1 218 ? 129.579 139.091 208.079 1.00 64.10  ? 218  PRO B C   1 
ATOM   8540  O  O   . PRO B 1 218 ? 129.309 139.085 209.282 1.00 64.10  ? 218  PRO B O   1 
ATOM   8541  C  CB  . PRO B 1 218 ? 131.809 140.137 207.539 1.00 64.10  ? 218  PRO B CB  1 
ATOM   8542  C  CG  . PRO B 1 218 ? 132.177 140.973 208.715 1.00 64.10  ? 218  PRO B CG  1 
ATOM   8543  C  CD  . PRO B 1 218 ? 131.204 142.111 208.730 1.00 64.10  ? 218  PRO B CD  1 
ATOM   8544  N  N   . VAL B 1 219 ? 129.276 138.087 207.262 1.00 63.44  ? 219  VAL B N   1 
ATOM   8545  C  CA  . VAL B 1 219 ? 128.595 136.883 207.714 1.00 63.44  ? 219  VAL B CA  1 
ATOM   8546  C  C   . VAL B 1 219 ? 129.527 135.695 207.534 1.00 63.44  ? 219  VAL B C   1 
ATOM   8547  O  O   . VAL B 1 219 ? 130.441 135.712 206.702 1.00 63.44  ? 219  VAL B O   1 
ATOM   8548  C  CB  . VAL B 1 219 ? 127.267 136.656 206.961 1.00 63.44  ? 219  VAL B CB  1 
ATOM   8549  C  CG1 . VAL B 1 219 ? 126.340 137.845 207.156 1.00 63.44  ? 219  VAL B CG1 1 
ATOM   8550  C  CG2 . VAL B 1 219 ? 127.529 136.413 205.484 1.00 63.44  ? 219  VAL B CG2 1 
ATOM   8551  N  N   . GLU B 1 220 ? 129.283 134.654 208.325 1.00 70.33  ? 220  GLU B N   1 
ATOM   8552  C  CA  . GLU B 1 220 ? 130.128 133.469 208.319 1.00 70.33  ? 220  GLU B CA  1 
ATOM   8553  C  C   . GLU B 1 220 ? 129.607 132.446 207.319 1.00 70.33  ? 220  GLU B C   1 
ATOM   8554  O  O   . GLU B 1 220 ? 128.410 132.147 207.287 1.00 70.33  ? 220  GLU B O   1 
ATOM   8555  C  CB  . GLU B 1 220 ? 130.189 132.856 209.718 1.00 70.33  ? 220  GLU B CB  1 
ATOM   8556  C  CG  . GLU B 1 220 ? 130.794 131.461 209.768 1.00 70.33  ? 220  GLU B CG  1 
ATOM   8557  C  CD  . GLU B 1 220 ? 132.290 131.464 209.545 1.00 70.33  ? 220  GLU B CD  1 
ATOM   8558  O  OE1 . GLU B 1 220 ? 132.931 132.498 209.821 1.00 70.33  ? 220  GLU B OE1 1 
ATOM   8559  O  OE2 . GLU B 1 220 ? 132.827 130.431 209.094 1.00 70.33  ? 220  GLU B OE2 1 
ATOM   8560  N  N   . LYS B 1 221 ? 130.509 131.913 206.501 1.00 77.48  ? 221  LYS B N   1 
ATOM   8561  C  CA  . LYS B 1 221 ? 130.197 130.843 205.562 1.00 77.48  ? 221  LYS B CA  1 
ATOM   8562  C  C   . LYS B 1 221 ? 130.951 129.591 205.989 1.00 77.48  ? 221  LYS B C   1 
ATOM   8563  O  O   . LYS B 1 221 ? 132.174 129.627 206.158 1.00 77.48  ? 221  LYS B O   1 
ATOM   8564  C  CB  . LYS B 1 221 ? 130.568 131.238 204.134 1.00 77.48  ? 221  LYS B CB  1 
ATOM   8565  C  CG  . LYS B 1 221 ? 129.781 132.413 203.583 1.00 77.48  ? 221  LYS B CG  1 
ATOM   8566  C  CD  . LYS B 1 221 ? 128.289 132.141 203.614 1.00 77.48  ? 221  LYS B CD  1 
ATOM   8567  C  CE  . LYS B 1 221 ? 127.522 133.220 202.872 1.00 77.48  ? 221  LYS B CE  1 
ATOM   8568  N  NZ  . LYS B 1 221 ? 126.118 133.337 203.349 1.00 77.48  ? 221  LYS B NZ  1 
ATOM   8569  N  N   . ALA B 1 222 ? 130.224 128.492 206.161 1.00 82.58  ? 222  ALA B N   1 
ATOM   8570  C  CA  . ALA B 1 222 ? 130.797 127.236 206.618 1.00 82.58  ? 222  ALA B CA  1 
ATOM   8571  C  C   . ALA B 1 222 ? 130.682 126.171 205.535 1.00 82.58  ? 222  ALA B C   1 
ATOM   8572  O  O   . ALA B 1 222 ? 129.921 126.307 204.573 1.00 82.58  ? 222  ALA B O   1 
ATOM   8573  C  CB  . ALA B 1 222 ? 130.112 126.754 207.900 1.00 82.58  ? 222  ALA B CB  1 
ATOM   8574  N  N   . ALA B 1 223 ? 131.466 125.104 205.703 1.00 88.06  ? 223  ALA B N   1 
ATOM   8575  C  CA  . ALA B 1 223 ? 131.415 123.989 204.762 1.00 88.06  ? 223  ALA B CA  1 
ATOM   8576  C  C   . ALA B 1 223 ? 130.047 123.319 204.772 1.00 88.06  ? 223  ALA B C   1 
ATOM   8577  O  O   . ALA B 1 223 ? 129.506 122.983 203.712 1.00 88.06  ? 223  ALA B O   1 
ATOM   8578  C  CB  . ALA B 1 223 ? 132.510 122.976 205.089 1.00 88.06  ? 223  ALA B CB  1 
ATOM   8579  N  N   . THR B 1 224 ? 129.476 123.115 205.955 1.00 88.20  ? 224  THR B N   1 
ATOM   8580  C  CA  . THR B 1 224 ? 128.155 122.526 206.110 1.00 88.20  ? 224  THR B CA  1 
ATOM   8581  C  C   . THR B 1 224 ? 127.240 123.524 206.804 1.00 88.20  ? 224  THR B C   1 
ATOM   8582  O  O   . THR B 1 224 ? 127.691 124.316 207.638 1.00 88.20  ? 224  THR B O   1 
ATOM   8583  C  CB  . THR B 1 224 ? 128.211 121.224 206.917 1.00 88.20  ? 224  THR B CB  1 
ATOM   8584  O  OG1 . THR B 1 224 ? 128.464 121.525 208.295 1.00 88.20  ? 224  THR B OG1 1 
ATOM   8585  C  CG2 . THR B 1 224 ? 129.312 120.316 206.391 1.00 88.20  ? 224  THR B CG2 1 
ATOM   8586  N  N   . THR B 1 225 ? 125.958 123.486 206.453 1.00 96.44  ? 225  THR B N   1 
ATOM   8587  C  CA  . THR B 1 225 ? 125.001 124.417 207.029 1.00 96.44  ? 225  THR B CA  1 
ATOM   8588  C  C   . THR B 1 225 ? 124.855 124.180 208.531 1.00 96.44  ? 225  THR B C   1 
ATOM   8589  O  O   . THR B 1 225 ? 124.941 123.053 209.026 1.00 96.44  ? 225  THR B O   1 
ATOM   8590  C  CB  . THR B 1 225 ? 123.641 124.290 206.338 1.00 96.44  ? 225  THR B CB  1 
ATOM   8591  O  OG1 . THR B 1 225 ? 122.700 125.170 206.965 1.00 96.44  ? 225  THR B OG1 1 
ATOM   8592  C  CG2 . THR B 1 225 ? 123.127 122.859 206.418 1.00 96.44  ? 225  THR B CG2 1 
ATOM   8593  N  N   . ARG B 1 226 ? 124.644 125.278 209.261 1.00 99.43  ? 226  ARG B N   1 
ATOM   8594  C  CA  . ARG B 1 226 ? 124.483 125.211 210.707 1.00 99.43  ? 226  ARG B CA  1 
ATOM   8595  C  C   . ARG B 1 226 ? 123.172 125.831 211.174 1.00 99.43  ? 226  ARG B C   1 
ATOM   8596  O  O   . ARG B 1 226 ? 123.008 126.058 212.380 1.00 99.43  ? 226  ARG B O   1 
ATOM   8597  C  CB  . ARG B 1 226 ? 125.659 125.901 211.410 1.00 99.43  ? 226  ARG B CB  1 
ATOM   8598  C  CG  . ARG B 1 226 ? 125.724 127.402 211.171 1.00 99.43  ? 226  ARG B CG  1 
ATOM   8599  C  CD  . ARG B 1 226 ? 126.865 128.045 211.944 1.00 99.43  ? 226  ARG B CD  1 
ATOM   8600  N  NE  . ARG B 1 226 ? 128.167 127.705 211.383 1.00 99.43  ? 226  ARG B NE  1 
ATOM   8601  C  CZ  . ARG B 1 226 ? 129.129 127.083 212.051 1.00 99.43  ? 226  ARG B CZ  1 
ATOM   8602  N  NH1 . ARG B 1 226 ? 128.970 126.719 213.313 1.00 99.43  ? 226  ARG B NH1 1 
ATOM   8603  N  NH2 . ARG B 1 226 ? 130.280 126.821 211.437 1.00 99.43  ? 226  ARG B NH2 1 
ATOM   8604  N  N   . GLN B 1 227 ? 122.238 126.108 210.268 1.00 105.19 ? 227  GLN B N   1 
ATOM   8605  C  CA  . GLN B 1 227 ? 120.987 126.768 210.593 1.00 105.19 ? 227  GLN B CA  1 
ATOM   8606  C  C   . GLN B 1 227 ? 119.827 126.001 209.973 1.00 105.19 ? 227  GLN B C   1 
ATOM   8607  O  O   . GLN B 1 227 ? 119.982 125.405 208.900 1.00 105.19 ? 227  GLN B O   1 
ATOM   8608  C  CB  . GLN B 1 227 ? 121.005 128.220 210.078 1.00 105.19 ? 227  GLN B CB  1 
ATOM   8609  C  CG  . GLN B 1 227 ? 119.732 129.016 210.315 1.00 105.19 ? 227  GLN B CG  1 
ATOM   8610  C  CD  . GLN B 1 227 ? 119.942 130.510 210.167 1.00 105.19 ? 227  GLN B CD  1 
ATOM   8611  O  OE1 . GLN B 1 227 ? 120.745 131.109 210.881 1.00 105.19 ? 227  GLN B OE1 1 
ATOM   8612  N  NE2 . GLN B 1 227 ? 119.217 131.120 209.237 1.00 105.19 ? 227  GLN B NE2 1 
ATOM   8613  N  N   . PRO B 1 228 ? 118.665 125.979 210.625 1.00 111.18 ? 228  PRO B N   1 
ATOM   8614  C  CA  . PRO B 1 228 ? 117.481 125.383 209.996 1.00 111.18 ? 228  PRO B CA  1 
ATOM   8615  C  C   . PRO B 1 228 ? 117.129 126.105 208.702 1.00 111.18 ? 228  PRO B C   1 
ATOM   8616  O  O   . PRO B 1 228 ? 117.414 127.292 208.534 1.00 111.18 ? 228  PRO B O   1 
ATOM   8617  C  CB  . PRO B 1 228 ? 116.387 125.552 211.059 1.00 111.18 ? 228  PRO B CB  1 
ATOM   8618  C  CG  . PRO B 1 228 ? 116.944 126.525 212.063 1.00 111.18 ? 228  PRO B CG  1 
ATOM   8619  C  CD  . PRO B 1 228 ? 118.419 126.320 212.035 1.00 111.18 ? 228  PRO B CD  1 
ATOM   8620  N  N   . GLU B 1 229 ? 116.514 125.365 207.779 1.00 114.40 ? 229  GLU B N   1 
ATOM   8621  C  CA  . GLU B 1 229 ? 116.260 125.871 206.435 1.00 114.40 ? 229  GLU B CA  1 
ATOM   8622  C  C   . GLU B 1 229 ? 115.444 127.156 206.467 1.00 114.40 ? 229  GLU B C   1 
ATOM   8623  O  O   . GLU B 1 229 ? 114.441 127.258 207.178 1.00 114.40 ? 229  GLU B O   1 
ATOM   8624  C  CB  . GLU B 1 229 ? 115.538 124.807 205.605 1.00 114.40 ? 229  GLU B CB  1 
ATOM   8625  C  CG  . GLU B 1 229 ? 115.453 125.126 204.117 1.00 114.40 ? 229  GLU B CG  1 
ATOM   8626  C  CD  . GLU B 1 229 ? 116.794 125.032 203.409 1.00 114.40 ? 229  GLU B CD  1 
ATOM   8627  O  OE1 . GLU B 1 229 ? 117.776 124.578 204.032 1.00 114.40 ? 229  GLU B OE1 1 
ATOM   8628  O  OE2 . GLU B 1 229 ? 116.866 125.418 202.223 1.00 114.40 ? 229  GLU B OE2 1 
ATOM   8629  N  N   . HIS B 1 230 ? 115.887 128.137 205.683 1.00 110.80 ? 230  HIS B N   1 
ATOM   8630  C  CA  . HIS B 1 230 ? 115.248 129.444 205.595 1.00 110.80 ? 230  HIS B CA  1 
ATOM   8631  C  C   . HIS B 1 230 ? 115.027 129.771 204.127 1.00 110.80 ? 230  HIS B C   1 
ATOM   8632  O  O   . HIS B 1 230 ? 115.830 129.376 203.276 1.00 110.80 ? 230  HIS B O   1 
ATOM   8633  C  CB  . HIS B 1 230 ? 116.104 130.520 206.268 1.00 110.80 ? 230  HIS B CB  1 
ATOM   8634  C  CG  . HIS B 1 230 ? 117.529 130.523 205.812 1.00 110.80 ? 230  HIS B CG  1 
ATOM   8635  N  ND1 . HIS B 1 230 ? 118.528 129.856 206.488 1.00 110.80 ? 230  HIS B ND1 1 
ATOM   8636  C  CD2 . HIS B 1 230 ? 118.121 131.101 204.741 1.00 110.80 ? 230  HIS B CD2 1 
ATOM   8637  C  CE1 . HIS B 1 230 ? 119.675 130.029 205.855 1.00 110.80 ? 230  HIS B CE1 1 
ATOM   8638  N  NE2 . HIS B 1 230 ? 119.455 130.780 204.792 1.00 110.80 ? 230  HIS B NE2 1 
ATOM   8639  N  N   . SER B 1 231 ? 113.941 130.490 203.835 1.00 112.21 ? 231  SER B N   1 
ATOM   8640  C  CA  . SER B 1 231 ? 113.557 130.745 202.450 1.00 112.21 ? 231  SER B CA  1 
ATOM   8641  C  C   . SER B 1 231 ? 114.599 131.582 201.715 1.00 112.21 ? 231  SER B C   1 
ATOM   8642  O  O   . SER B 1 231 ? 114.928 131.305 200.556 1.00 112.21 ? 231  SER B O   1 
ATOM   8643  C  CB  . SER B 1 231 ? 112.192 131.434 202.409 1.00 112.21 ? 231  SER B CB  1 
ATOM   8644  O  OG  . SER B 1 231 ? 112.213 132.652 203.133 1.00 112.21 ? 231  SER B OG  1 
ATOM   8645  N  N   . ASN B 1 232 ? 115.127 132.616 202.374 1.00 107.65 ? 232  ASN B N   1 
ATOM   8646  C  CA  . ASN B 1 232 ? 116.004 133.593 201.735 1.00 107.65 ? 232  ASN B CA  1 
ATOM   8647  C  C   . ASN B 1 232 ? 117.269 132.938 201.191 1.00 107.65 ? 232  ASN B C   1 
ATOM   8648  O  O   . ASN B 1 232 ? 118.097 132.442 201.965 1.00 107.65 ? 232  ASN B O   1 
ATOM   8649  C  CB  . ASN B 1 232 ? 116.368 134.707 202.719 1.00 107.65 ? 232  ASN B CB  1 
ATOM   8650  C  CG  . ASN B 1 232 ? 116.985 135.913 202.034 1.00 107.65 ? 232  ASN B CG  1 
ATOM   8651  O  OD1 . ASN B 1 232 ? 117.181 135.922 200.819 1.00 107.65 ? 232  ASN B OD1 1 
ATOM   8652  N  ND2 . ASN B 1 232 ? 117.290 136.943 202.814 1.00 107.65 ? 232  ASN B ND2 1 
ATOM   8653  N  N   . PRO B 1 233 ? 117.447 132.911 199.866 1.00 104.69 ? 233  PRO B N   1 
ATOM   8654  C  CA  . PRO B 1 233 ? 118.674 132.313 199.313 1.00 104.69 ? 233  PRO B CA  1 
ATOM   8655  C  C   . PRO B 1 233 ? 119.940 133.046 199.721 1.00 104.69 ? 233  PRO B C   1 
ATOM   8656  O  O   . PRO B 1 233 ? 120.986 132.410 199.897 1.00 104.69 ? 233  PRO B O   1 
ATOM   8657  C  CB  . PRO B 1 233 ? 118.441 132.379 197.795 1.00 104.69 ? 233  PRO B CB  1 
ATOM   8658  C  CG  . PRO B 1 233 ? 116.959 132.585 197.634 1.00 104.69 ? 233  PRO B CG  1 
ATOM   8659  C  CD  . PRO B 1 233 ? 116.556 133.413 198.809 1.00 104.69 ? 233  PRO B CD  1 
ATOM   8660  N  N   . LEU B 1 234 ? 119.879 134.369 199.873 1.00 100.19 ? 234  LEU B N   1 
ATOM   8661  C  CA  . LEU B 1 234 ? 121.072 135.146 200.193 1.00 100.19 ? 234  LEU B CA  1 
ATOM   8662  C  C   . LEU B 1 234 ? 121.539 134.961 201.628 1.00 100.19 ? 234  LEU B C   1 
ATOM   8663  O  O   . LEU B 1 234 ? 122.658 135.378 201.950 1.00 100.19 ? 234  LEU B O   1 
ATOM   8664  C  CB  . LEU B 1 234 ? 120.821 136.630 199.919 1.00 100.19 ? 234  LEU B CB  1 
ATOM   8665  C  CG  . LEU B 1 234 ? 120.377 136.986 198.499 1.00 100.19 ? 234  LEU B CG  1 
ATOM   8666  C  CD1 . LEU B 1 234 ? 120.307 138.494 198.319 1.00 100.19 ? 234  LEU B CD1 1 
ATOM   8667  C  CD2 . LEU B 1 234 ? 121.316 136.367 197.477 1.00 100.19 ? 234  LEU B CD2 1 
ATOM   8668  N  N   . GLU B 1 235 ? 120.726 134.358 202.494 1.00 103.78 ? 235  GLU B N   1 
ATOM   8669  C  CA  . GLU B 1 235 ? 121.123 134.115 203.874 1.00 103.78 ? 235  GLU B CA  1 
ATOM   8670  C  C   . GLU B 1 235 ? 121.724 132.735 204.094 1.00 103.78 ? 235  GLU B C   1 
ATOM   8671  O  O   . GLU B 1 235 ? 122.082 132.411 205.232 1.00 103.78 ? 235  GLU B O   1 
ATOM   8672  C  CB  . GLU B 1 235 ? 119.925 134.293 204.814 1.00 103.78 ? 235  GLU B CB  1 
ATOM   8673  C  CG  . GLU B 1 235 ? 119.476 135.734 204.979 1.00 103.78 ? 235  GLU B CG  1 
ATOM   8674  C  CD  . GLU B 1 235 ? 118.270 135.867 205.888 1.00 103.78 ? 235  GLU B CD  1 
ATOM   8675  O  OE1 . GLU B 1 235 ? 117.683 134.827 206.254 1.00 103.78 ? 235  GLU B OE1 1 
ATOM   8676  O  OE2 . GLU B 1 235 ? 117.911 137.010 206.239 1.00 103.78 ? 235  GLU B OE2 1 
ATOM   8677  N  N   . CYS B 1 236 ? 121.833 131.919 203.049 1.00 99.74  ? 236  CYS B N   1 
ATOM   8678  C  CA  . CYS B 1 236 ? 122.410 130.588 203.184 1.00 99.74  ? 236  CYS B CA  1 
ATOM   8679  C  C   . CYS B 1 236 ? 123.853 130.676 203.658 1.00 99.74  ? 236  CYS B C   1 
ATOM   8680  O  O   . CYS B 1 236 ? 124.661 131.416 203.091 1.00 99.74  ? 236  CYS B O   1 
ATOM   8681  C  CB  . CYS B 1 236 ? 122.331 129.845 201.849 1.00 99.74  ? 236  CYS B CB  1 
ATOM   8682  S  SG  . CYS B 1 236 ? 120.648 129.571 201.243 1.00 99.74  ? 236  CYS B SG  1 
ATOM   8683  N  N   . ASP B 1 237 ? 124.172 129.914 204.703 1.00 91.88  ? 237  ASP B N   1 
ATOM   8684  C  CA  . ASP B 1 237 ? 125.495 129.926 205.308 1.00 91.88  ? 237  ASP B CA  1 
ATOM   8685  C  C   . ASP B 1 237 ? 126.472 128.995 204.601 1.00 91.88  ? 237  ASP B C   1 
ATOM   8686  O  O   . ASP B 1 237 ? 127.584 128.785 205.097 1.00 91.88  ? 237  ASP B O   1 
ATOM   8687  C  CB  . ASP B 1 237 ? 125.399 129.560 206.790 1.00 91.88  ? 237  ASP B CB  1 
ATOM   8688  C  CG  . ASP B 1 237 ? 124.661 130.606 207.601 1.00 91.88  ? 237  ASP B CG  1 
ATOM   8689  O  OD1 . ASP B 1 237 ? 124.687 131.791 207.210 1.00 91.88  ? 237  ASP B OD1 1 
ATOM   8690  O  OD2 . ASP B 1 237 ? 124.055 130.243 208.631 1.00 91.88  ? 237  ASP B OD2 1 
ATOM   8691  N  N   . THR B 1 238 ? 126.082 128.433 203.458 1.00 90.12  ? 238  THR B N   1 
ATOM   8692  C  CA  . THR B 1 238 ? 126.947 127.537 202.702 1.00 90.12  ? 238  THR B CA  1 
ATOM   8693  C  C   . THR B 1 238 ? 127.103 127.912 201.237 1.00 90.12  ? 238  THR B C   1 
ATOM   8694  O  O   . THR B 1 238 ? 127.941 127.307 200.557 1.00 90.12  ? 238  THR B O   1 
ATOM   8695  C  CB  . THR B 1 238 ? 126.431 126.093 202.785 1.00 90.12  ? 238  THR B CB  1 
ATOM   8696  O  OG1 . THR B 1 238 ? 127.325 125.222 202.082 1.00 90.12  ? 238  THR B OG1 1 
ATOM   8697  C  CG2 . THR B 1 238 ? 125.044 125.991 202.176 1.00 90.12  ? 238  THR B CG2 1 
ATOM   8698  N  N   . LEU B 1 239 ? 126.340 128.874 200.727 1.00 86.81  ? 239  LEU B N   1 
ATOM   8699  C  CA  . LEU B 1 239 ? 126.427 129.300 199.337 1.00 86.81  ? 239  LEU B CA  1 
ATOM   8700  C  C   . LEU B 1 239 ? 126.935 130.732 199.268 1.00 86.81  ? 239  LEU B C   1 
ATOM   8701  O  O   . LEU B 1 239 ? 126.455 131.603 200.001 1.00 86.81  ? 239  LEU B O   1 
ATOM   8702  C  CB  . LEU B 1 239 ? 125.069 129.199 198.641 1.00 86.81  ? 239  LEU B CB  1 
ATOM   8703  C  CG  . LEU B 1 239 ? 124.491 127.805 198.401 1.00 86.81  ? 239  LEU B CG  1 
ATOM   8704  C  CD1 . LEU B 1 239 ? 123.148 127.920 197.708 1.00 86.81  ? 239  LEU B CD1 1 
ATOM   8705  C  CD2 . LEU B 1 239 ? 125.447 126.957 197.581 1.00 86.81  ? 239  LEU B CD2 1 
ATOM   8706  N  N   . CYS B 1 240 ? 127.905 130.970 198.391 1.00 83.68  ? 240  CYS B N   1 
ATOM   8707  C  CA  . CYS B 1 240 ? 128.362 132.316 198.098 1.00 83.68  ? 240  CYS B CA  1 
ATOM   8708  C  C   . CYS B 1 240 ? 127.590 132.865 196.900 1.00 83.68  ? 240  CYS B C   1 
ATOM   8709  O  O   . CYS B 1 240 ? 126.830 132.154 196.239 1.00 83.68  ? 240  CYS B O   1 
ATOM   8710  C  CB  . CYS B 1 240 ? 129.869 132.326 197.847 1.00 83.68  ? 240  CYS B CB  1 
ATOM   8711  S  SG  . CYS B 1 240 ? 130.863 131.870 199.284 1.00 83.68  ? 240  CYS B SG  1 
ATOM   8712  N  N   . PHE B 1 241 ? 127.784 134.149 196.611 1.00 81.14  ? 241  PHE B N   1 
ATOM   8713  C  CA  . PHE B 1 241 ? 127.080 134.799 195.516 1.00 81.14  ? 241  PHE B CA  1 
ATOM   8714  C  C   . PHE B 1 241 ? 127.995 135.812 194.849 1.00 81.14  ? 241  PHE B C   1 
ATOM   8715  O  O   . PHE B 1 241 ? 128.805 136.462 195.516 1.00 81.14  ? 241  PHE B O   1 
ATOM   8716  C  CB  . PHE B 1 241 ? 125.801 135.487 196.008 1.00 81.14  ? 241  PHE B CB  1 
ATOM   8717  C  CG  . PHE B 1 241 ? 124.698 134.533 196.360 1.00 81.14  ? 241  PHE B CG  1 
ATOM   8718  C  CD1 . PHE B 1 241 ? 123.935 133.939 195.370 1.00 81.14  ? 241  PHE B CD1 1 
ATOM   8719  C  CD2 . PHE B 1 241 ? 124.424 134.228 197.682 1.00 81.14  ? 241  PHE B CD2 1 
ATOM   8720  C  CE1 . PHE B 1 241 ? 122.919 133.061 195.692 1.00 81.14  ? 241  PHE B CE1 1 
ATOM   8721  C  CE2 . PHE B 1 241 ? 123.410 133.351 198.010 1.00 81.14  ? 241  PHE B CE2 1 
ATOM   8722  C  CZ  . PHE B 1 241 ? 122.656 132.767 197.014 1.00 81.14  ? 241  PHE B CZ  1 
ATOM   8723  N  N   . MET B 1 242 ? 127.855 135.944 193.532 1.00 79.45  ? 242  MET B N   1 
ATOM   8724  C  CA  . MET B 1 242 ? 128.690 136.867 192.777 1.00 79.45  ? 242  MET B CA  1 
ATOM   8725  C  C   . MET B 1 242 ? 128.416 138.307 193.196 1.00 79.45  ? 242  MET B C   1 
ATOM   8726  O  O   . MET B 1 242 ? 127.275 138.697 193.456 1.00 79.45  ? 242  MET B O   1 
ATOM   8727  C  CB  . MET B 1 242 ? 128.446 136.700 191.277 1.00 79.45  ? 242  MET B CB  1 
ATOM   8728  C  CG  . MET B 1 242 ? 129.429 137.456 190.400 1.00 79.45  ? 242  MET B CG  1 
ATOM   8729  S  SD  . MET B 1 242 ? 129.090 137.259 188.641 1.00 79.45  ? 242  MET B SD  1 
ATOM   8730  C  CE  . MET B 1 242 ? 130.386 138.272 187.932 1.00 79.45  ? 242  MET B CE  1 
ATOM   8731  N  N   . GLY B 1 243 ? 129.483 139.101 193.258 1.00 74.83  ? 243  GLY B N   1 
ATOM   8732  C  CA  . GLY B 1 243 ? 129.395 140.481 193.677 1.00 74.83  ? 243  GLY B CA  1 
ATOM   8733  C  C   . GLY B 1 243 ? 129.818 140.744 195.106 1.00 74.83  ? 243  GLY B C   1 
ATOM   8734  O  O   . GLY B 1 243 ? 129.969 141.912 195.485 1.00 74.83  ? 243  GLY B O   1 
ATOM   8735  N  N   . THR B 1 244 ? 130.014 139.704 195.907 1.00 69.39  ? 244  THR B N   1 
ATOM   8736  C  CA  . THR B 1 244 ? 130.434 139.843 197.291 1.00 69.39  ? 244  THR B CA  1 
ATOM   8737  C  C   . THR B 1 244 ? 131.916 139.516 197.431 1.00 69.39  ? 244  THR B C   1 
ATOM   8738  O  O   . THR B 1 244 ? 132.512 138.846 196.585 1.00 69.39  ? 244  THR B O   1 
ATOM   8739  C  CB  . THR B 1 244 ? 129.606 138.934 198.202 1.00 69.39  ? 244  THR B CB  1 
ATOM   8740  O  OG1 . THR B 1 244 ? 129.699 137.581 197.740 1.00 69.39  ? 244  THR B OG1 1 
ATOM   8741  C  CG2 . THR B 1 244 ? 128.149 139.364 198.191 1.00 69.39  ? 244  THR B CG2 1 
ATOM   8742  N  N   . THR B 1 245 ? 132.507 140.005 198.517 1.00 62.54  ? 245  THR B N   1 
ATOM   8743  C  CA  . THR B 1 245 ? 133.924 139.826 198.792 1.00 62.54  ? 245  THR B CA  1 
ATOM   8744  C  C   . THR B 1 245 ? 134.127 138.970 200.034 1.00 62.54  ? 245  THR B C   1 
ATOM   8745  O  O   . THR B 1 245 ? 133.220 138.789 200.850 1.00 62.54  ? 245  THR B O   1 
ATOM   8746  C  CB  . THR B 1 245 ? 134.621 141.175 198.982 1.00 62.54  ? 245  THR B CB  1 
ATOM   8747  O  OG1 . THR B 1 245 ? 134.072 141.839 200.126 1.00 62.54  ? 245  THR B OG1 1 
ATOM   8748  C  CG2 . THR B 1 245 ? 134.420 142.043 197.764 1.00 62.54  ? 245  THR B CG2 1 
ATOM   8749  N  N   . VAL B 1 246 ? 135.340 138.447 200.168 1.00 58.75  ? 246  VAL B N   1 
ATOM   8750  C  CA  . VAL B 1 246 ? 135.740 137.656 201.325 1.00 58.75  ? 246  VAL B CA  1 
ATOM   8751  C  C   . VAL B 1 246 ? 136.499 138.578 202.269 1.00 58.75  ? 246  VAL B C   1 
ATOM   8752  O  O   . VAL B 1 246 ? 137.622 139.001 201.972 1.00 58.75  ? 246  VAL B O   1 
ATOM   8753  C  CB  . VAL B 1 246 ? 136.592 136.447 200.917 1.00 58.75  ? 246  VAL B CB  1 
ATOM   8754  C  CG1 . VAL B 1 246 ? 137.194 135.787 202.144 1.00 58.75  ? 246  VAL B CG1 1 
ATOM   8755  C  CG2 . VAL B 1 246 ? 135.756 135.452 200.129 1.00 58.75  ? 246  VAL B CG2 1 
ATOM   8756  N  N   . VAL B 1 247 ? 135.883 138.902 203.406 1.00 59.47  ? 247  VAL B N   1 
ATOM   8757  C  CA  . VAL B 1 247 ? 136.523 139.790 204.371 1.00 59.47  ? 247  VAL B CA  1 
ATOM   8758  C  C   . VAL B 1 247 ? 137.723 139.106 205.013 1.00 59.47  ? 247  VAL B C   1 
ATOM   8759  O  O   . VAL B 1 247 ? 138.809 139.688 205.112 1.00 59.47  ? 247  VAL B O   1 
ATOM   8760  C  CB  . VAL B 1 247 ? 135.508 140.255 205.429 1.00 59.47  ? 247  VAL B CB  1 
ATOM   8761  C  CG1 . VAL B 1 247 ? 136.223 140.894 206.606 1.00 59.47  ? 247  VAL B CG1 1 
ATOM   8762  C  CG2 . VAL B 1 247 ? 134.521 141.228 204.817 1.00 59.47  ? 247  VAL B CG2 1 
ATOM   8763  N  N   . SER B 1 248 ? 137.551 137.862 205.450 1.00 62.38  ? 248  SER B N   1 
ATOM   8764  C  CA  . SER B 1 248 ? 138.615 137.177 206.172 1.00 62.38  ? 248  SER B CA  1 
ATOM   8765  C  C   . SER B 1 248 ? 138.421 135.672 206.058 1.00 62.38  ? 248  SER B C   1 
ATOM   8766  O  O   . SER B 1 248 ? 137.346 135.188 205.702 1.00 62.38  ? 248  SER B O   1 
ATOM   8767  C  CB  . SER B 1 248 ? 138.653 137.606 207.642 1.00 62.38  ? 248  SER B CB  1 
ATOM   8768  O  OG  . SER B 1 248 ? 137.547 137.077 208.351 1.00 62.38  ? 248  SER B OG  1 
ATOM   8769  N  N   . GLY B 1 249 ? 139.479 134.938 206.391 1.00 66.54  ? 249  GLY B N   1 
ATOM   8770  C  CA  . GLY B 1 249 ? 139.436 133.491 206.375 1.00 66.54  ? 249  GLY B CA  1 
ATOM   8771  C  C   . GLY B 1 249 ? 139.747 132.911 205.013 1.00 66.54  ? 249  GLY B C   1 
ATOM   8772  O  O   . GLY B 1 249 ? 139.926 133.613 204.014 1.00 66.54  ? 249  GLY B O   1 
ATOM   8773  N  N   . THR B 1 250 ? 139.812 131.582 204.978 1.00 75.23  ? 250  THR B N   1 
ATOM   8774  C  CA  . THR B 1 250 ? 140.135 130.857 203.759 1.00 75.23  ? 250  THR B CA  1 
ATOM   8775  C  C   . THR B 1 250 ? 139.007 129.890 203.436 1.00 75.23  ? 250  THR B C   1 
ATOM   8776  O  O   . THR B 1 250 ? 138.213 129.524 204.303 1.00 75.23  ? 250  THR B O   1 
ATOM   8777  C  CB  . THR B 1 250 ? 141.461 130.093 203.884 1.00 75.23  ? 250  THR B CB  1 
ATOM   8778  O  OG1 . THR B 1 250 ? 141.385 129.177 204.983 1.00 75.23  ? 250  THR B OG1 1 
ATOM   8779  C  CG2 . THR B 1 250 ? 142.613 131.059 204.115 1.00 75.23  ? 250  THR B CG2 1 
ATOM   8780  N  N   . ALA B 1 251 ? 138.930 129.484 202.172 1.00 76.05  ? 251  ALA B N   1 
ATOM   8781  C  CA  . ALA B 1 251 ? 137.897 128.533 201.787 1.00 76.05  ? 251  ALA B CA  1 
ATOM   8782  C  C   . ALA B 1 251 ? 138.290 127.835 200.496 1.00 76.05  ? 251  ALA B C   1 
ATOM   8783  O  O   . ALA B 1 251 ? 139.147 128.305 199.748 1.00 76.05  ? 251  ALA B O   1 
ATOM   8784  C  CB  . ALA B 1 251 ? 136.536 129.217 201.622 1.00 76.05  ? 251  ALA B CB  1 
ATOM   8785  N  N   . GLN B 1 252 ? 137.642 126.700 200.252 1.00 83.54  ? 252  GLN B N   1 
ATOM   8786  C  CA  . GLN B 1 252 ? 137.682 126.028 198.959 1.00 83.54  ? 252  GLN B CA  1 
ATOM   8787  C  C   . GLN B 1 252 ? 136.252 125.670 198.593 1.00 83.54  ? 252  GLN B C   1 
ATOM   8788  O  O   . GLN B 1 252 ? 135.557 125.018 199.379 1.00 83.54  ? 252  GLN B O   1 
ATOM   8789  C  CB  . GLN B 1 252 ? 138.568 124.780 198.994 1.00 83.54  ? 252  GLN B CB  1 
ATOM   8790  C  CG  . GLN B 1 252 ? 139.234 124.461 197.666 1.00 83.54  ? 252  GLN B CG  1 
ATOM   8791  C  CD  . GLN B 1 252 ? 140.096 123.217 197.730 1.00 83.54  ? 252  GLN B CD  1 
ATOM   8792  O  OE1 . GLN B 1 252 ? 139.591 122.095 197.691 1.00 83.54  ? 252  GLN B OE1 1 
ATOM   8793  N  NE2 . GLN B 1 252 ? 141.406 123.409 197.830 1.00 83.54  ? 252  GLN B NE2 1 
ATOM   8794  N  N   . ALA B 1 253 ? 135.813 126.103 197.413 1.00 85.74  ? 253  ALA B N   1 
ATOM   8795  C  CA  . ALA B 1 253 ? 134.421 125.985 197.008 1.00 85.74  ? 253  ALA B CA  1 
ATOM   8796  C  C   . ALA B 1 253 ? 134.328 125.500 195.568 1.00 85.74  ? 253  ALA B C   1 
ATOM   8797  O  O   . ALA B 1 253 ? 135.331 125.372 194.859 1.00 85.74  ? 253  ALA B O   1 
ATOM   8798  C  CB  . ALA B 1 253 ? 133.681 127.320 197.165 1.00 85.74  ? 253  ALA B CB  1 
ATOM   8799  N  N   . MET B 1 254 ? 133.096 125.228 195.146 1.00 95.73  ? 254  MET B N   1 
ATOM   8800  C  CA  . MET B 1 254 ? 132.790 124.746 193.807 1.00 95.73  ? 254  MET B CA  1 
ATOM   8801  C  C   . MET B 1 254 ? 131.793 125.682 193.140 1.00 95.73  ? 254  MET B C   1 
ATOM   8802  O  O   . MET B 1 254 ? 130.821 126.116 193.766 1.00 95.73  ? 254  MET B O   1 
ATOM   8803  C  CB  . MET B 1 254 ? 132.219 123.325 193.851 1.00 95.73  ? 254  MET B CB  1 
ATOM   8804  C  CG  . MET B 1 254 ? 131.717 122.812 192.512 1.00 95.73  ? 254  MET B CG  1 
ATOM   8805  S  SD  . MET B 1 254 ? 130.996 121.167 192.632 1.00 95.73  ? 254  MET B SD  1 
ATOM   8806  C  CE  . MET B 1 254 ? 132.441 120.210 193.073 1.00 95.73  ? 254  MET B CE  1 
ATOM   8807  N  N   . VAL B 1 255 ? 132.030 125.982 191.866 1.00 90.67  ? 255  VAL B N   1 
ATOM   8808  C  CA  . VAL B 1 255 ? 131.135 126.844 191.101 1.00 90.67  ? 255  VAL B CA  1 
ATOM   8809  C  C   . VAL B 1 255 ? 129.877 126.058 190.755 1.00 90.67  ? 255  VAL B C   1 
ATOM   8810  O  O   . VAL B 1 255 ? 129.954 124.955 190.203 1.00 90.67  ? 255  VAL B O   1 
ATOM   8811  C  CB  . VAL B 1 255 ? 131.824 127.370 189.835 1.00 90.67  ? 255  VAL B CB  1 
ATOM   8812  C  CG1 . VAL B 1 255 ? 130.920 128.355 189.113 1.00 90.67  ? 255  VAL B CG1 1 
ATOM   8813  C  CG2 . VAL B 1 255 ? 133.154 128.018 190.182 1.00 90.67  ? 255  VAL B CG2 1 
ATOM   8814  N  N   . ILE B 1 256 ? 128.716 126.621 191.081 1.00 93.20  ? 256  ILE B N   1 
ATOM   8815  C  CA  . ILE B 1 256 ? 127.442 125.979 190.785 1.00 93.20  ? 256  ILE B CA  1 
ATOM   8816  C  C   . ILE B 1 256 ? 126.636 126.726 189.730 1.00 93.20  ? 256  ILE B C   1 
ATOM   8817  O  O   . ILE B 1 256 ? 125.697 126.142 189.167 1.00 93.20  ? 256  ILE B O   1 
ATOM   8818  C  CB  . ILE B 1 256 ? 126.599 125.793 192.063 1.00 93.20  ? 256  ILE B CB  1 
ATOM   8819  C  CG1 . ILE B 1 256 ? 126.064 127.138 192.555 1.00 93.20  ? 256  ILE B CG1 1 
ATOM   8820  C  CG2 . ILE B 1 256 ? 127.421 125.118 193.145 1.00 93.20  ? 256  ILE B CG2 1 
ATOM   8821  C  CD1 . ILE B 1 256 ? 125.103 127.023 193.717 1.00 93.20  ? 256  ILE B CD1 1 
ATOM   8822  N  N   . ALA B 1 257 ? 126.961 127.984 189.445 1.00 92.55  ? 257  ALA B N   1 
ATOM   8823  C  CA  . ALA B 1 257 ? 126.292 128.737 188.395 1.00 92.55  ? 257  ALA B CA  1 
ATOM   8824  C  C   . ALA B 1 257 ? 127.287 129.734 187.825 1.00 92.55  ? 257  ALA B C   1 
ATOM   8825  O  O   . ALA B 1 257 ? 128.258 130.111 188.485 1.00 92.55  ? 257  ALA B O   1 
ATOM   8826  C  CB  . ALA B 1 257 ? 125.040 129.449 188.917 1.00 92.55  ? 257  ALA B CB  1 
ATOM   8827  N  N   . THR B 1 258 ? 127.035 130.158 186.590 1.00 91.09  ? 258  THR B N   1 
ATOM   8828  C  CA  . THR B 1 258 ? 127.970 131.032 185.899 1.00 91.09  ? 258  THR B CA  1 
ATOM   8829  C  C   . THR B 1 258 ? 127.216 131.868 184.875 1.00 91.09  ? 258  THR B C   1 
ATOM   8830  O  O   . THR B 1 258 ? 126.097 131.540 184.473 1.00 91.09  ? 258  THR B O   1 
ATOM   8831  C  CB  . THR B 1 258 ? 129.089 130.228 185.228 1.00 91.09  ? 258  THR B CB  1 
ATOM   8832  O  OG1 . THR B 1 258 ? 130.196 131.090 184.950 1.00 91.09  ? 258  THR B OG1 1 
ATOM   8833  C  CG2 . THR B 1 258 ? 128.599 129.611 183.928 1.00 91.09  ? 258  THR B CG2 1 
ATOM   8834  N  N   . GLY B 1 259 ? 127.853 132.959 184.456 1.00 91.17  ? 259  GLY B N   1 
ATOM   8835  C  CA  . GLY B 1 259 ? 127.265 133.832 183.453 1.00 91.17  ? 259  GLY B CA  1 
ATOM   8836  C  C   . GLY B 1 259 ? 125.934 134.396 183.905 1.00 91.17  ? 259  GLY B C   1 
ATOM   8837  O  O   . GLY B 1 259 ? 125.770 134.838 185.047 1.00 91.17  ? 259  GLY B O   1 
ATOM   8838  N  N   . ALA B 1 260 ? 124.963 134.381 182.992 1.00 95.99  ? 260  ALA B N   1 
ATOM   8839  C  CA  . ALA B 1 260 ? 123.620 134.855 183.299 1.00 95.99  ? 260  ALA B CA  1 
ATOM   8840  C  C   . ALA B 1 260 ? 122.862 133.926 184.237 1.00 95.99  ? 260  ALA B C   1 
ATOM   8841  O  O   . ALA B 1 260 ? 121.875 134.356 184.843 1.00 95.99  ? 260  ALA B O   1 
ATOM   8842  C  CB  . ALA B 1 260 ? 122.821 135.045 182.008 1.00 95.99  ? 260  ALA B CB  1 
ATOM   8843  N  N   . ASN B 1 261 ? 123.293 132.669 184.367 1.00 95.40  ? 261  ASN B N   1 
ATOM   8844  C  CA  . ASN B 1 261 ? 122.633 131.744 185.282 1.00 95.40  ? 261  ASN B CA  1 
ATOM   8845  C  C   . ASN B 1 261 ? 122.884 132.102 186.740 1.00 95.40  ? 261  ASN B C   1 
ATOM   8846  O  O   . ASN B 1 261 ? 122.185 131.593 187.623 1.00 95.40  ? 261  ASN B O   1 
ATOM   8847  C  CB  . ASN B 1 261 ? 123.100 130.315 185.003 1.00 95.40  ? 261  ASN B CB  1 
ATOM   8848  C  CG  . ASN B 1 261 ? 122.690 129.827 183.628 1.00 95.40  ? 261  ASN B CG  1 
ATOM   8849  O  OD1 . ASN B 1 261 ? 121.570 130.071 183.179 1.00 95.40  ? 261  ASN B OD1 1 
ATOM   8850  N  ND2 . ASN B 1 261 ? 123.600 129.139 182.949 1.00 95.40  ? 261  ASN B ND2 1 
ATOM   8851  N  N   . THR B 1 262 ? 123.865 132.960 187.009 1.00 94.60  ? 262  THR B N   1 
ATOM   8852  C  CA  . THR B 1 262 ? 124.157 133.384 188.370 1.00 94.60  ? 262  THR B CA  1 
ATOM   8853  C  C   . THR B 1 262 ? 123.005 134.226 188.910 1.00 94.60  ? 262  THR B C   1 
ATOM   8854  O  O   . THR B 1 262 ? 122.204 134.768 188.144 1.00 94.60  ? 262  THR B O   1 
ATOM   8855  C  CB  . THR B 1 262 ? 125.466 134.178 188.392 1.00 94.60  ? 262  THR B CB  1 
ATOM   8856  O  OG1 . THR B 1 262 ? 126.481 133.433 187.709 1.00 94.60  ? 262  THR B OG1 1 
ATOM   8857  C  CG2 . THR B 1 262 ? 125.938 134.427 189.818 1.00 94.60  ? 262  THR B CG2 1 
ATOM   8858  N  N   . TRP B 1 263 ? 122.909 134.310 190.239 1.00 95.69  ? 263  TRP B N   1 
ATOM   8859  C  CA  . TRP B 1 263 ? 121.869 135.083 190.910 1.00 95.69  ? 263  TRP B CA  1 
ATOM   8860  C  C   . TRP B 1 263 ? 121.775 136.498 190.354 1.00 95.69  ? 263  TRP B C   1 
ATOM   8861  O  O   . TRP B 1 263 ? 120.678 136.976 190.048 1.00 95.69  ? 263  TRP B O   1 
ATOM   8862  C  CB  . TRP B 1 263 ? 122.129 135.121 192.420 1.00 95.69  ? 263  TRP B CB  1 
ATOM   8863  C  CG  . TRP B 1 263 ? 121.269 136.097 193.179 1.00 95.69  ? 263  TRP B CG  1 
ATOM   8864  C  CD1 . TRP B 1 263 ? 121.463 137.445 193.301 1.00 95.69  ? 263  TRP B CD1 1 
ATOM   8865  C  CD2 . TRP B 1 263 ? 120.082 135.797 193.923 1.00 95.69  ? 263  TRP B CD2 1 
ATOM   8866  N  NE1 . TRP B 1 263 ? 120.471 137.999 194.072 1.00 95.69  ? 263  TRP B NE1 1 
ATOM   8867  C  CE2 . TRP B 1 263 ? 119.611 137.009 194.466 1.00 95.69  ? 263  TRP B CE2 1 
ATOM   8868  C  CE3 . TRP B 1 263 ? 119.372 134.621 194.182 1.00 95.69  ? 263  TRP B CE3 1 
ATOM   8869  C  CZ2 . TRP B 1 263 ? 118.463 137.078 195.253 1.00 95.69  ? 263  TRP B CZ2 1 
ATOM   8870  C  CZ3 . TRP B 1 263 ? 118.233 134.692 194.962 1.00 95.69  ? 263  TRP B CZ3 1 
ATOM   8871  C  CH2 . TRP B 1 263 ? 117.790 135.912 195.488 1.00 95.69  ? 263  TRP B CH2 1 
ATOM   8872  N  N   . PHE B 1 264 ? 122.915 137.181 190.224 1.00 96.27  ? 264  PHE B N   1 
ATOM   8873  C  CA  . PHE B 1 264 ? 122.893 138.529 189.665 1.00 96.27  ? 264  PHE B CA  1 
ATOM   8874  C  C   . PHE B 1 264 ? 122.631 138.500 188.165 1.00 96.27  ? 264  PHE B C   1 
ATOM   8875  O  O   . PHE B 1 264 ? 122.165 139.491 187.591 1.00 96.27  ? 264  PHE B O   1 
ATOM   8876  C  CB  . PHE B 1 264 ? 124.204 139.256 189.953 1.00 96.27  ? 264  PHE B CB  1 
ATOM   8877  C  CG  . PHE B 1 264 ? 124.282 140.612 189.317 1.00 96.27  ? 264  PHE B CG  1 
ATOM   8878  C  CD1 . PHE B 1 264 ? 123.485 141.649 189.773 1.00 96.27  ? 264  PHE B CD1 1 
ATOM   8879  C  CD2 . PHE B 1 264 ? 125.116 140.840 188.237 1.00 96.27  ? 264  PHE B CD2 1 
ATOM   8880  C  CE1 . PHE B 1 264 ? 123.542 142.897 189.184 1.00 96.27  ? 264  PHE B CE1 1 
ATOM   8881  C  CE2 . PHE B 1 264 ? 125.177 142.084 187.645 1.00 96.27  ? 264  PHE B CE2 1 
ATOM   8882  C  CZ  . PHE B 1 264 ? 124.388 143.114 188.118 1.00 96.27  ? 264  PHE B CZ  1 
ATOM   8883  N  N   . GLY B 1 265 ? 122.934 137.378 187.513 1.00 99.85  ? 265  GLY B N   1 
ATOM   8884  C  CA  . GLY B 1 265 ? 122.732 137.258 186.083 1.00 99.85  ? 265  GLY B CA  1 
ATOM   8885  C  C   . GLY B 1 265 ? 121.298 137.539 185.688 1.00 99.85  ? 265  GLY B C   1 
ATOM   8886  O  O   . GLY B 1 265 ? 121.040 138.207 184.682 1.00 99.85  ? 265  GLY B O   1 
ATOM   8887  N  N   . GLN B 1 266 ? 120.354 137.032 186.480 1.00 106.63 ? 266  GLN B N   1 
ATOM   8888  C  CA  . GLN B 1 266 ? 118.957 137.408 186.297 1.00 106.63 ? 266  GLN B CA  1 
ATOM   8889  C  C   . GLN B 1 266 ? 118.723 138.853 186.724 1.00 106.63 ? 266  GLN B C   1 
ATOM   8890  O  O   . GLN B 1 266 ? 118.091 139.630 185.998 1.00 106.63 ? 266  GLN B O   1 
ATOM   8891  C  CB  . GLN B 1 266 ? 118.051 136.457 187.081 1.00 106.63 ? 266  GLN B CB  1 
ATOM   8892  C  CG  . GLN B 1 266 ? 117.791 135.127 186.389 1.00 106.63 ? 266  GLN B CG  1 
ATOM   8893  C  CD  . GLN B 1 266 ? 119.017 134.235 186.355 1.00 106.63 ? 266  GLN B CD  1 
ATOM   8894  O  OE1 . GLN B 1 266 ? 119.580 133.894 187.394 1.00 106.63 ? 266  GLN B OE1 1 
ATOM   8895  N  NE2 . GLN B 1 266 ? 119.440 133.856 185.155 1.00 106.63 ? 266  GLN B NE2 1 
ATOM   8896  N  N   . LEU B 1 267 ? 119.242 139.233 187.891 1.00 108.47 ? 267  LEU B N   1 
ATOM   8897  C  CA  . LEU B 1 267 ? 119.000 140.544 188.481 1.00 108.47 ? 267  LEU B CA  1 
ATOM   8898  C  C   . LEU B 1 267 ? 119.478 141.668 187.573 1.00 108.47 ? 267  LEU B C   1 
ATOM   8899  O  O   . LEU B 1 267 ? 120.675 141.791 187.293 1.00 108.47 ? 267  LEU B O   1 
ATOM   8900  C  CB  . LEU B 1 267 ? 119.700 140.634 189.839 1.00 108.47 ? 267  LEU B CB  1 
ATOM   8901  N  N   . ALA B 1 268 ? 118.526 142.470 187.090 1.00 113.85 ? 268  ALA B N   1 
ATOM   8902  C  CA  . ALA B 1 268 ? 118.775 143.649 186.264 1.00 113.85 ? 268  ALA B CA  1 
ATOM   8903  C  C   . ALA B 1 268 ? 119.329 143.279 184.893 1.00 113.85 ? 268  ALA B C   1 
ATOM   8904  O  O   . ALA B 1 268 ? 119.496 144.148 184.032 1.00 113.85 ? 268  ALA B O   1 
ATOM   8905  C  CB  . ALA B 1 268 ? 119.721 144.624 186.975 1.00 113.85 ? 268  ALA B CB  1 
ATOM   8906  N  N   . GLY B 1 269 ? 119.613 141.994 184.679 1.00 114.06 ? 269  GLY B N   1 
ATOM   8907  C  CA  . GLY B 1 269 ? 119.997 141.544 183.351 1.00 114.06 ? 269  GLY B CA  1 
ATOM   8908  C  C   . GLY B 1 269 ? 118.852 140.871 182.624 1.00 114.06 ? 269  GLY B C   1 
ATOM   8909  O  O   . GLY B 1 269 ? 118.587 141.152 181.453 1.00 114.06 ? 269  GLY B O   1 
ATOM   8910  N  N   . ARG B 1 270 ? 118.156 139.978 183.311 1.00 118.46 ? 270  ARG B N   1 
ATOM   8911  C  CA  . ARG B 1 270 ? 116.985 139.292 182.781 1.00 118.46 ? 270  ARG B CA  1 
ATOM   8912  C  C   . ARG B 1 270 ? 115.753 139.475 183.653 1.00 118.46 ? 270  ARG B C   1 
ATOM   8913  O  O   . ARG B 1 270 ? 114.634 139.450 183.136 1.00 118.46 ? 270  ARG B O   1 
ATOM   8914  C  CB  . ARG B 1 270 ? 117.284 137.794 182.608 1.00 118.46 ? 270  ARG B CB  1 
ATOM   8915  N  N   . VAL B 1 271 ? 115.931 139.650 184.965 1.00 122.11 ? 271  VAL B N   1 
ATOM   8916  C  CA  . VAL B 1 271 ? 114.791 139.899 185.844 1.00 122.11 ? 271  VAL B CA  1 
ATOM   8917  C  C   . VAL B 1 271 ? 114.128 141.223 185.491 1.00 122.11 ? 271  VAL B C   1 
ATOM   8918  O  O   . VAL B 1 271 ? 112.898 141.316 185.405 1.00 122.11 ? 271  VAL B O   1 
ATOM   8919  C  CB  . VAL B 1 271 ? 115.234 139.864 187.318 1.00 122.11 ? 271  VAL B CB  1 
ATOM   8920  N  N   . SER B 1 272 ? 114.931 142.265 185.281 1.00 121.82 ? 272  SER B N   1 
ATOM   8921  C  CA  . SER B 1 272 ? 114.433 143.564 184.846 1.00 121.82 ? 272  SER B CA  1 
ATOM   8922  C  C   . SER B 1 272 ? 114.485 143.722 183.332 1.00 121.82 ? 272  SER B C   1 
ATOM   8923  O  O   . SER B 1 272 ? 113.449 143.945 182.699 1.00 121.82 ? 272  SER B O   1 
ATOM   8924  C  CB  . SER B 1 272 ? 115.232 144.686 185.520 1.00 121.82 ? 272  SER B CB  1 
ATOM   8925  N  N   . GLU B 1 273 ? 115.675 143.601 182.744 1.00 124.26 ? 273  GLU B N   1 
ATOM   8926  C  CA  . GLU B 1 273 ? 115.868 143.680 181.296 1.00 124.26 ? 273  GLU B CA  1 
ATOM   8927  C  C   . GLU B 1 273 ? 115.261 144.960 180.727 1.00 124.26 ? 273  GLU B C   1 
ATOM   8928  O  O   . GLU B 1 273 ? 114.589 144.962 179.693 1.00 124.26 ? 273  GLU B O   1 
ATOM   8929  C  CB  . GLU B 1 273 ? 115.297 142.444 180.601 1.00 124.26 ? 273  GLU B CB  1 
ATOM   8930  N  N   . GLN B 1 274 ? 115.504 146.064 181.423 1.00 119.48 ? 274  GLN B N   1 
ATOM   8931  C  CA  . GLN B 1 274 ? 114.989 147.366 181.032 1.00 119.48 ? 274  GLN B CA  1 
ATOM   8932  C  C   . GLN B 1 274 ? 116.012 148.110 180.180 1.00 119.48 ? 274  GLN B C   1 
ATOM   8933  O  O   . GLN B 1 274 ? 117.185 147.739 180.097 1.00 119.48 ? 274  GLN B O   1 
ATOM   8934  C  CB  . GLN B 1 274 ? 114.619 148.191 182.269 1.00 119.48 ? 274  GLN B CB  1 
ATOM   8935  N  N   . GLU B 1 275 ? 115.546 149.179 179.538 1.00 104.83 ? 275  GLU B N   1 
ATOM   8936  C  CA  . GLU B 1 275 ? 116.401 150.003 178.690 1.00 104.83 ? 275  GLU B CA  1 
ATOM   8937  C  C   . GLU B 1 275 ? 117.221 150.933 179.575 1.00 104.83 ? 275  GLU B C   1 
ATOM   8938  O  O   . GLU B 1 275 ? 116.670 151.817 180.240 1.00 104.83 ? 275  GLU B O   1 
ATOM   8939  C  CB  . GLU B 1 275 ? 115.560 150.792 177.691 1.00 104.83 ? 275  GLU B CB  1 
ATOM   8940  N  N   . SER B 1 276 ? 118.537 150.736 179.586 1.00 87.41  ? 276  SER B N   1 
ATOM   8941  C  CA  . SER B 1 276 ? 119.411 151.553 180.416 1.00 87.41  ? 276  SER B CA  1 
ATOM   8942  C  C   . SER B 1 276 ? 119.515 152.963 179.848 1.00 87.41  ? 276  SER B C   1 
ATOM   8943  O  O   . SER B 1 276 ? 119.701 153.147 178.641 1.00 87.41  ? 276  SER B O   1 
ATOM   8944  C  CB  . SER B 1 276 ? 120.796 150.915 180.513 1.00 87.41  ? 276  SER B CB  1 
ATOM   8945  N  N   . GLU B 1 277 ? 119.391 153.956 180.720 1.00 72.20  ? 277  GLU B N   1 
ATOM   8946  C  CA  . GLU B 1 277 ? 119.488 155.339 180.284 1.00 72.20  ? 277  GLU B CA  1 
ATOM   8947  C  C   . GLU B 1 277 ? 120.926 155.651 179.871 1.00 72.20  ? 277  GLU B C   1 
ATOM   8948  O  O   . GLU B 1 277 ? 121.865 155.354 180.619 1.00 72.20  ? 277  GLU B O   1 
ATOM   8949  C  CB  . GLU B 1 277 ? 119.035 156.283 181.399 1.00 72.20  ? 277  GLU B CB  1 
ATOM   8950  C  CG  . GLU B 1 277 ? 118.718 157.698 180.940 1.00 72.20  ? 277  GLU B CG  1 
ATOM   8951  C  CD  . GLU B 1 277 ? 119.915 158.623 181.022 1.00 72.20  ? 277  GLU B CD  1 
ATOM   8952  O  OE1 . GLU B 1 277 ? 120.770 158.413 181.908 1.00 72.20  ? 277  GLU B OE1 1 
ATOM   8953  O  OE2 . GLU B 1 277 ? 120.002 159.561 180.202 1.00 72.20  ? 277  GLU B OE2 1 
ATOM   8954  N  N   . PRO B 1 278 ? 121.135 156.232 178.690 1.00 61.32  ? 278  PRO B N   1 
ATOM   8955  C  CA  . PRO B 1 278 ? 122.501 156.496 178.225 1.00 61.32  ? 278  PRO B CA  1 
ATOM   8956  C  C   . PRO B 1 278 ? 123.222 157.504 179.109 1.00 61.32  ? 278  PRO B C   1 
ATOM   8957  O  O   . PRO B 1 278 ? 122.621 158.397 179.708 1.00 61.32  ? 278  PRO B O   1 
ATOM   8958  C  CB  . PRO B 1 278 ? 122.297 157.047 176.808 1.00 61.32  ? 278  PRO B CB  1 
ATOM   8959  C  CG  . PRO B 1 278 ? 120.876 157.506 176.769 1.00 61.32  ? 278  PRO B CG  1 
ATOM   8960  C  CD  . PRO B 1 278 ? 120.126 156.588 177.680 1.00 61.32  ? 278  PRO B CD  1 
ATOM   8961  N  N   . ASN B 1 279 ? 124.544 157.349 179.175 1.00 52.68  ? 279  ASN B N   1 
ATOM   8962  C  CA  . ASN B 1 279 ? 125.382 158.221 179.989 1.00 52.68  ? 279  ASN B CA  1 
ATOM   8963  C  C   . ASN B 1 279 ? 125.697 159.519 179.258 1.00 52.68  ? 279  ASN B C   1 
ATOM   8964  O  O   . ASN B 1 279 ? 125.086 159.824 178.229 1.00 52.68  ? 279  ASN B O   1 
ATOM   8965  C  CB  . ASN B 1 279 ? 126.673 157.501 180.385 1.00 52.68  ? 279  ASN B CB  1 
ATOM   8966  C  CG  . ASN B 1 279 ? 127.389 156.891 179.196 1.00 52.68  ? 279  ASN B CG  1 
ATOM   8967  O  OD1 . ASN B 1 279 ? 127.008 157.107 178.046 1.00 52.68  ? 279  ASN B OD1 1 
ATOM   8968  N  ND2 . ASN B 1 279 ? 128.434 156.119 179.470 1.00 52.68  ? 279  ASN B ND2 1 
ATOM   8969  N  N   . ALA B 1 280 ? 126.645 160.292 179.788 1.00 46.22  ? 280  ALA B N   1 
ATOM   8970  C  CA  . ALA B 1 280 ? 126.991 161.599 179.215 1.00 46.22  ? 280  ALA B CA  1 
ATOM   8971  C  C   . ALA B 1 280 ? 127.544 161.461 177.799 1.00 46.22  ? 280  ALA B C   1 
ATOM   8972  O  O   . ALA B 1 280 ? 127.166 162.216 176.900 1.00 46.22  ? 280  ALA B O   1 
ATOM   8973  C  CB  . ALA B 1 280 ? 127.985 162.321 180.127 1.00 46.22  ? 280  ALA B CB  1 
ATOM   8974  N  N   . PHE B 1 281 ? 128.445 160.499 177.593 1.00 45.26  ? 281  PHE B N   1 
ATOM   8975  C  CA  . PHE B 1 281 ? 129.088 160.329 176.295 1.00 45.26  ? 281  PHE B CA  1 
ATOM   8976  C  C   . PHE B 1 281 ? 128.091 159.923 175.216 1.00 45.26  ? 281  PHE B C   1 
ATOM   8977  O  O   . PHE B 1 281 ? 128.070 160.496 174.120 1.00 45.26  ? 281  PHE B O   1 
ATOM   8978  C  CB  . PHE B 1 281 ? 130.204 159.288 176.403 1.00 45.26  ? 281  PHE B CB  1 
ATOM   8979  C  CG  . PHE B 1 281 ? 131.115 159.253 175.215 1.00 45.26  ? 281  PHE B CG  1 
ATOM   8980  C  CD1 . PHE B 1 281 ? 131.958 160.316 174.943 1.00 45.26  ? 281  PHE B CD1 1 
ATOM   8981  C  CD2 . PHE B 1 281 ? 131.130 158.161 174.368 1.00 45.26  ? 281  PHE B CD2 1 
ATOM   8982  C  CE1 . PHE B 1 281 ? 132.799 160.289 173.854 1.00 45.26  ? 281  PHE B CE1 1 
ATOM   8983  C  CE2 . PHE B 1 281 ? 131.969 158.129 173.275 1.00 45.26  ? 281  PHE B CE2 1 
ATOM   8984  C  CZ  . PHE B 1 281 ? 132.804 159.195 173.019 1.00 45.26  ? 281  PHE B CZ  1 
ATOM   8985  N  N   . GLN B 1 282 ? 127.264 158.920 175.517 1.00 51.59  ? 282  GLN B N   1 
ATOM   8986  C  CA  . GLN B 1 282 ? 126.294 158.440 174.539 1.00 51.59  ? 282  GLN B CA  1 
ATOM   8987  C  C   . GLN B 1 282 ? 125.308 159.535 174.162 1.00 51.59  ? 282  GLN B C   1 
ATOM   8988  O  O   . GLN B 1 282 ? 124.924 159.660 172.994 1.00 51.59  ? 282  GLN B O   1 
ATOM   8989  C  CB  . GLN B 1 282 ? 125.557 157.216 175.085 1.00 51.59  ? 282  GLN B CB  1 
ATOM   8990  C  CG  . GLN B 1 282 ? 126.358 155.926 175.015 1.00 51.59  ? 282  GLN B CG  1 
ATOM   8991  C  CD  . GLN B 1 282 ? 125.594 154.738 175.564 1.00 51.59  ? 282  GLN B CD  1 
ATOM   8992  O  OE1 . GLN B 1 282 ? 124.834 154.863 176.524 1.00 51.59  ? 282  GLN B OE1 1 
ATOM   8993  N  NE2 . GLN B 1 282 ? 125.789 153.575 174.953 1.00 51.59  ? 282  GLN B NE2 1 
ATOM   8994  N  N   . GLN B 1 283 ? 124.890 160.343 175.138 1.00 53.13  ? 283  GLN B N   1 
ATOM   8995  C  CA  . GLN B 1 283 ? 124.001 161.460 174.841 1.00 53.13  ? 283  GLN B CA  1 
ATOM   8996  C  C   . GLN B 1 283 ? 124.656 162.465 173.902 1.00 53.13  ? 283  GLN B C   1 
ATOM   8997  O  O   . GLN B 1 283 ? 124.013 162.939 172.960 1.00 53.13  ? 283  GLN B O   1 
ATOM   8998  C  CB  . GLN B 1 283 ? 123.569 162.147 176.135 1.00 53.13  ? 283  GLN B CB  1 
ATOM   8999  C  CG  . GLN B 1 283 ? 122.472 161.418 176.893 1.00 53.13  ? 283  GLN B CG  1 
ATOM   9000  C  CD  . GLN B 1 283 ? 122.267 161.968 178.290 1.00 53.13  ? 283  GLN B CD  1 
ATOM   9001  O  OE1 . GLN B 1 283 ? 122.962 162.891 178.715 1.00 53.13  ? 283  GLN B OE1 1 
ATOM   9002  N  NE2 . GLN B 1 283 ? 121.306 161.405 179.012 1.00 53.13  ? 283  GLN B NE2 1 
ATOM   9003  N  N   . GLY B 1 284 ? 125.928 162.795 174.134 1.00 52.79  ? 284  GLY B N   1 
ATOM   9004  C  CA  . GLY B 1 284 ? 126.610 163.727 173.249 1.00 52.79  ? 284  GLY B CA  1 
ATOM   9005  C  C   . GLY B 1 284 ? 126.777 163.178 171.845 1.00 52.79  ? 284  GLY B C   1 
ATOM   9006  O  O   . GLY B 1 284 ? 126.608 163.898 170.855 1.00 52.79  ? 284  GLY B O   1 
ATOM   9007  N  N   . ILE B 1 285 ? 127.120 161.893 171.740 1.00 48.92  ? 285  ILE B N   1 
ATOM   9008  C  CA  . ILE B 1 285 ? 127.256 161.267 170.429 1.00 48.92  ? 285  ILE B CA  1 
ATOM   9009  C  C   . ILE B 1 285 ? 125.919 161.262 169.699 1.00 48.92  ? 285  ILE B C   1 
ATOM   9010  O  O   . ILE B 1 285 ? 125.853 161.524 168.491 1.00 48.92  ? 285  ILE B O   1 
ATOM   9011  C  CB  . ILE B 1 285 ? 127.834 159.849 170.572 1.00 48.92  ? 285  ILE B CB  1 
ATOM   9012  C  CG1 . ILE B 1 285 ? 129.251 159.909 171.143 1.00 48.92  ? 285  ILE B CG1 1 
ATOM   9013  C  CG2 . ILE B 1 285 ? 127.834 159.134 169.234 1.00 48.92  ? 285  ILE B CG2 1 
ATOM   9014  C  CD1 . ILE B 1 285 ? 130.195 160.765 170.335 1.00 48.92  ? 285  ILE B CD1 1 
ATOM   9015  N  N   . SER B 1 286 ? 124.834 160.965 170.418 1.00 52.81  ? 286  SER B N   1 
ATOM   9016  C  CA  . SER B 1 286 ? 123.508 161.006 169.813 1.00 52.81  ? 286  SER B CA  1 
ATOM   9017  C  C   . SER B 1 286 ? 123.158 162.413 169.351 1.00 52.81  ? 286  SER B C   1 
ATOM   9018  O  O   . SER B 1 286 ? 122.566 162.591 168.282 1.00 52.81  ? 286  SER B O   1 
ATOM   9019  C  CB  . SER B 1 286 ? 122.464 160.489 170.802 1.00 52.81  ? 286  SER B CB  1 
ATOM   9020  O  OG  . SER B 1 286 ? 121.158 160.592 170.262 1.00 52.81  ? 286  SER B OG  1 
ATOM   9021  N  N   . ARG B 1 287 ? 123.512 163.427 170.144 1.00 54.42  ? 287  ARG B N   1 
ATOM   9022  C  CA  . ARG B 1 287 ? 123.260 164.807 169.740 1.00 54.42  ? 287  ARG B CA  1 
ATOM   9023  C  C   . ARG B 1 287 ? 124.016 165.154 168.464 1.00 54.42  ? 287  ARG B C   1 
ATOM   9024  O  O   . ARG B 1 287 ? 123.461 165.770 167.546 1.00 54.42  ? 287  ARG B O   1 
ATOM   9025  C  CB  . ARG B 1 287 ? 123.645 165.766 170.867 1.00 54.42  ? 287  ARG B CB  1 
ATOM   9026  C  CG  . ARG B 1 287 ? 122.749 165.694 172.090 1.00 54.42  ? 287  ARG B CG  1 
ATOM   9027  C  CD  . ARG B 1 287 ? 121.388 166.304 171.802 1.00 54.42  ? 287  ARG B CD  1 
ATOM   9028  N  NE  . ARG B 1 287 ? 121.486 167.724 171.483 1.00 54.42  ? 287  ARG B NE  1 
ATOM   9029  C  CZ  . ARG B 1 287 ? 121.534 168.694 172.385 1.00 54.42  ? 287  ARG B CZ  1 
ATOM   9030  N  NH1 . ARG B 1 287 ? 121.493 168.435 173.682 1.00 54.42  ? 287  ARG B NH1 1 
ATOM   9031  N  NH2 . ARG B 1 287 ? 121.627 169.956 171.976 1.00 54.42  ? 287  ARG B NH2 1 
ATOM   9032  N  N   . VAL B 1 288 ? 125.290 164.762 168.388 1.00 52.53  ? 288  VAL B N   1 
ATOM   9033  C  CA  . VAL B 1 288 ? 126.090 165.052 167.199 1.00 52.53  ? 288  VAL B CA  1 
ATOM   9034  C  C   . VAL B 1 288 ? 125.503 164.355 165.976 1.00 52.53  ? 288  VAL B C   1 
ATOM   9035  O  O   . VAL B 1 288 ? 125.367 164.957 164.900 1.00 52.53  ? 288  VAL B O   1 
ATOM   9036  C  CB  . VAL B 1 288 ? 127.557 164.646 167.432 1.00 52.53  ? 288  VAL B CB  1 
ATOM   9037  C  CG1 . VAL B 1 288 ? 128.340 164.708 166.132 1.00 52.53  ? 288  VAL B CG1 1 
ATOM   9038  C  CG2 . VAL B 1 288 ? 128.193 165.543 168.481 1.00 52.53  ? 288  VAL B CG2 1 
ATOM   9039  N  N   . SER B 1 289 ? 125.144 163.077 166.123 1.00 56.96  ? 289  SER B N   1 
ATOM   9040  C  CA  . SER B 1 289 ? 124.572 162.336 165.005 1.00 56.96  ? 289  SER B CA  1 
ATOM   9041  C  C   . SER B 1 289 ? 123.247 162.943 164.563 1.00 56.96  ? 289  SER B C   1 
ATOM   9042  O  O   . SER B 1 289 ? 122.977 163.049 163.361 1.00 56.96  ? 289  SER B O   1 
ATOM   9043  C  CB  . SER B 1 289 ? 124.389 160.869 165.387 1.00 56.96  ? 289  SER B CB  1 
ATOM   9044  O  OG  . SER B 1 289 ? 123.597 160.193 164.427 1.00 56.96  ? 289  SER B OG  1 
ATOM   9045  N  N   . MET B 1 290 ? 122.411 163.351 165.519 1.00 59.18  ? 290  MET B N   1 
ATOM   9046  C  CA  . MET B 1 290 ? 121.131 163.960 165.178 1.00 59.18  ? 290  MET B CA  1 
ATOM   9047  C  C   . MET B 1 290 ? 121.331 165.284 164.454 1.00 59.18  ? 290  MET B C   1 
ATOM   9048  O  O   . MET B 1 290 ? 120.605 165.600 163.507 1.00 59.18  ? 290  MET B O   1 
ATOM   9049  C  CB  . MET B 1 290 ? 120.292 164.153 166.441 1.00 59.18  ? 290  MET B CB  1 
ATOM   9050  C  CG  . MET B 1 290 ? 119.383 162.978 166.765 1.00 59.18  ? 290  MET B CG  1 
ATOM   9051  S  SD  . MET B 1 290 ? 118.111 162.693 165.519 1.00 59.18  ? 290  MET B SD  1 
ATOM   9052  C  CE  . MET B 1 290 ? 117.439 164.342 165.332 1.00 59.18  ? 290  MET B CE  1 
ATOM   9053  N  N   . LEU B 1 291 ? 122.311 166.079 164.892 1.00 55.48  ? 291  LEU B N   1 
ATOM   9054  C  CA  . LEU B 1 291 ? 122.588 167.347 164.224 1.00 55.48  ? 291  LEU B CA  1 
ATOM   9055  C  C   . LEU B 1 291 ? 123.041 167.121 162.786 1.00 55.48  ? 291  LEU B C   1 
ATOM   9056  O  O   . LEU B 1 291 ? 122.589 167.810 161.859 1.00 55.48  ? 291  LEU B O   1 
ATOM   9057  C  CB  . LEU B 1 291 ? 123.643 168.127 165.008 1.00 55.48  ? 291  LEU B CB  1 
ATOM   9058  C  CG  . LEU B 1 291 ? 124.015 169.511 164.477 1.00 55.48  ? 291  LEU B CG  1 
ATOM   9059  C  CD1 . LEU B 1 291 ? 122.835 170.460 164.595 1.00 55.48  ? 291  LEU B CD1 1 
ATOM   9060  C  CD2 . LEU B 1 291 ? 125.217 170.054 165.228 1.00 55.48  ? 291  LEU B CD2 1 
ATOM   9061  N  N   . LEU B 1 292 ? 123.936 166.150 162.581 1.00 55.36  ? 292  LEU B N   1 
ATOM   9062  C  CA  . LEU B 1 292 ? 124.367 165.835 161.222 1.00 55.36  ? 292  LEU B CA  1 
ATOM   9063  C  C   . LEU B 1 292 ? 123.208 165.337 160.368 1.00 55.36  ? 292  LEU B C   1 
ATOM   9064  O  O   . LEU B 1 292 ? 123.100 165.710 159.193 1.00 55.36  ? 292  LEU B O   1 
ATOM   9065  C  CB  . LEU B 1 292 ? 125.494 164.804 161.247 1.00 55.36  ? 292  LEU B CB  1 
ATOM   9066  C  CG  . LEU B 1 292 ? 126.784 165.244 161.939 1.00 55.36  ? 292  LEU B CG  1 
ATOM   9067  C  CD1 . LEU B 1 292 ? 127.821 164.138 161.894 1.00 55.36  ? 292  LEU B CD1 1 
ATOM   9068  C  CD2 . LEU B 1 292 ? 127.324 166.511 161.299 1.00 55.36  ? 292  LEU B CD2 1 
ATOM   9069  N  N   . ILE B 1 293 ? 122.333 164.506 160.939 1.00 58.64  ? 293  ILE B N   1 
ATOM   9070  C  CA  . ILE B 1 293 ? 121.175 164.014 160.198 1.00 58.64  ? 293  ILE B CA  1 
ATOM   9071  C  C   . ILE B 1 293 ? 120.255 165.166 159.818 1.00 58.64  ? 293  ILE B C   1 
ATOM   9072  O  O   . ILE B 1 293 ? 119.727 165.213 158.702 1.00 58.64  ? 293  ILE B O   1 
ATOM   9073  C  CB  . ILE B 1 293 ? 120.430 162.941 161.011 1.00 58.64  ? 293  ILE B CB  1 
ATOM   9074  C  CG1 . ILE B 1 293 ? 121.261 161.663 161.089 1.00 58.64  ? 293  ILE B CG1 1 
ATOM   9075  C  CG2 . ILE B 1 293 ? 119.072 162.647 160.400 1.00 58.64  ? 293  ILE B CG2 1 
ATOM   9076  C  CD1 . ILE B 1 293 ? 120.688 160.630 162.020 1.00 58.64  ? 293  ILE B CD1 1 
ATOM   9077  N  N   . ARG B 1 294 ? 120.036 166.102 160.740 1.00 58.21  ? 294  ARG B N   1 
ATOM   9078  C  CA  . ARG B 1 294 ? 119.203 167.264 160.456 1.00 58.21  ? 294  ARG B CA  1 
ATOM   9079  C  C   . ARG B 1 294 ? 119.777 168.057 159.292 1.00 58.21  ? 294  ARG B C   1 
ATOM   9080  O  O   . ARG B 1 294 ? 119.059 168.372 158.337 1.00 58.21  ? 294  ARG B O   1 
ATOM   9081  C  CB  . ARG B 1 294 ? 119.075 168.161 161.689 1.00 58.21  ? 294  ARG B CB  1 
ATOM   9082  C  CG  . ARG B 1 294 ? 118.258 167.571 162.826 1.00 58.21  ? 294  ARG B CG  1 
ATOM   9083  C  CD  . ARG B 1 294 ? 117.916 168.635 163.857 1.00 58.21  ? 294  ARG B CD  1 
ATOM   9084  N  NE  . ARG B 1 294 ? 117.517 168.055 165.134 1.00 58.21  ? 294  ARG B NE  1 
ATOM   9085  C  CZ  . ARG B 1 294 ? 118.101 168.324 166.293 1.00 58.21  ? 294  ARG B CZ  1 
ATOM   9086  N  NH1 . ARG B 1 294 ? 119.118 169.166 166.375 1.00 58.21  ? 294  ARG B NH1 1 
ATOM   9087  N  NH2 . ARG B 1 294 ? 117.654 167.734 167.398 1.00 58.21  ? 294  ARG B NH2 1 
ATOM   9088  N  N   . PHE B 1 295 ? 121.074 168.368 159.354 1.00 57.55  ? 295  PHE B N   1 
ATOM   9089  C  CA  . PHE B 1 295 ? 121.693 169.145 158.283 1.00 57.55  ? 295  PHE B CA  1 
ATOM   9090  C  C   . PHE B 1 295 ? 121.590 168.425 156.941 1.00 57.55  ? 295  PHE B C   1 
ATOM   9091  O  O   . PHE B 1 295 ? 121.246 169.030 155.916 1.00 57.55  ? 295  PHE B O   1 
ATOM   9092  C  CB  . PHE B 1 295 ? 123.156 169.436 158.627 1.00 57.55  ? 295  PHE B CB  1 
ATOM   9093  C  CG  . PHE B 1 295 ? 123.356 170.717 159.382 1.00 57.55  ? 295  PHE B CG  1 
ATOM   9094  C  CD1 . PHE B 1 295 ? 122.809 170.888 160.642 1.00 57.55  ? 295  PHE B CD1 1 
ATOM   9095  C  CD2 . PHE B 1 295 ? 124.088 171.754 158.830 1.00 57.55  ? 295  PHE B CD2 1 
ATOM   9096  C  CE1 . PHE B 1 295 ? 122.992 172.067 161.339 1.00 57.55  ? 295  PHE B CE1 1 
ATOM   9097  C  CE2 . PHE B 1 295 ? 124.274 172.934 159.522 1.00 57.55  ? 295  PHE B CE2 1 
ATOM   9098  C  CZ  . PHE B 1 295 ? 123.725 173.091 160.778 1.00 57.55  ? 295  PHE B CZ  1 
ATOM   9099  N  N   . MET B 1 296 ? 121.875 167.120 156.939 1.00 62.03  ? 296  MET B N   1 
ATOM   9100  C  CA  . MET B 1 296 ? 121.823 166.347 155.703 1.00 62.03  ? 296  MET B CA  1 
ATOM   9101  C  C   . MET B 1 296 ? 120.410 166.310 155.130 1.00 62.03  ? 296  MET B C   1 
ATOM   9102  O  O   . MET B 1 296 ? 120.193 166.634 153.957 1.00 62.03  ? 296  MET B O   1 
ATOM   9103  C  CB  . MET B 1 296 ? 122.342 164.934 155.963 1.00 62.03  ? 296  MET B CB  1 
ATOM   9104  C  CG  . MET B 1 296 ? 122.168 163.976 154.806 1.00 62.03  ? 296  MET B CG  1 
ATOM   9105  S  SD  . MET B 1 296 ? 122.588 162.289 155.277 1.00 62.03  ? 296  MET B SD  1 
ATOM   9106  C  CE  . MET B 1 296 ? 121.307 161.958 156.483 1.00 62.03  ? 296  MET B CE  1 
ATOM   9107  N  N   . LEU B 1 297 ? 119.434 165.924 155.945 1.00 62.68  ? 297  LEU B N   1 
ATOM   9108  C  CA  . LEU B 1 297 ? 118.044 165.816 155.518 1.00 62.68  ? 297  LEU B CA  1 
ATOM   9109  C  C   . LEU B 1 297 ? 117.426 167.149 155.196 1.00 62.68  ? 297  LEU B C   1 
ATOM   9110  O  O   . LEU B 1 297 ? 116.359 167.175 154.571 1.00 62.68  ? 297  LEU B O   1 
ATOM   9111  C  CB  . LEU B 1 297 ? 117.225 165.107 156.598 1.00 62.68  ? 297  LEU B CB  1 
ATOM   9112  C  CG  . LEU B 1 297 ? 117.478 163.606 156.750 1.00 62.68  ? 297  LEU B CG  1 
ATOM   9113  C  CD1 . LEU B 1 297 ? 116.405 162.965 157.614 1.00 62.68  ? 297  LEU B CD1 1 
ATOM   9114  C  CD2 . LEU B 1 297 ? 117.549 162.931 155.388 1.00 62.68  ? 297  LEU B CD2 1 
ATOM   9115  N  N   . VAL B 1 298 ? 118.029 168.262 155.605 1.00 63.34  ? 298  VAL B N   1 
ATOM   9116  C  CA  . VAL B 1 298 ? 117.577 169.591 155.208 1.00 63.34  ? 298  VAL B CA  1 
ATOM   9117  C  C   . VAL B 1 298 ? 118.163 169.995 153.858 1.00 63.34  ? 298  VAL B C   1 
ATOM   9118  O  O   . VAL B 1 298 ? 117.446 170.480 152.981 1.00 63.34  ? 298  VAL B O   1 
ATOM   9119  C  CB  . VAL B 1 298 ? 117.898 170.639 156.297 1.00 63.34  ? 298  VAL B CB  1 
ATOM   9120  C  CG1 . VAL B 1 298 ? 117.820 172.043 155.724 1.00 63.34  ? 298  VAL B CG1 1 
ATOM   9121  C  CG2 . VAL B 1 298 ? 116.930 170.500 157.460 1.00 63.34  ? 298  VAL B CG2 1 
ATOM   9122  N  N   . MET B 1 299 ? 119.469 169.786 153.662 1.00 66.64  ? 299  MET B N   1 
ATOM   9123  C  CA  . MET B 1 299 ? 120.110 170.384 152.493 1.00 66.64  ? 299  MET B CA  1 
ATOM   9124  C  C   . MET B 1 299 ? 120.101 169.457 151.281 1.00 66.64  ? 299  MET B C   1 
ATOM   9125  O  O   . MET B 1 299 ? 119.948 169.927 150.147 1.00 66.64  ? 299  MET B O   1 
ATOM   9126  C  CB  . MET B 1 299 ? 121.530 170.827 152.839 1.00 66.64  ? 299  MET B CB  1 
ATOM   9127  C  CG  . MET B 1 299 ? 121.547 172.159 153.564 1.00 66.64  ? 299  MET B CG  1 
ATOM   9128  S  SD  . MET B 1 299 ? 123.179 172.826 153.914 1.00 66.64  ? 299  MET B SD  1 
ATOM   9129  C  CE  . MET B 1 299 ? 122.714 174.377 154.682 1.00 66.64  ? 299  MET B CE  1 
ATOM   9130  N  N   . ALA B 1 300 ? 120.274 168.149 151.480 1.00 69.90  ? 300  ALA B N   1 
ATOM   9131  C  CA  . ALA B 1 300 ? 120.301 167.234 150.338 1.00 69.90  ? 300  ALA B CA  1 
ATOM   9132  C  C   . ALA B 1 300 ? 119.005 167.236 149.530 1.00 69.90  ? 300  ALA B C   1 
ATOM   9133  O  O   . ALA B 1 300 ? 119.081 167.271 148.288 1.00 69.90  ? 300  ALA B O   1 
ATOM   9134  C  CB  . ALA B 1 300 ? 120.662 165.824 150.818 1.00 69.90  ? 300  ALA B CB  1 
ATOM   9135  N  N   . PRO B 1 301 ? 117.808 167.182 150.134 1.00 73.73  ? 301  PRO B N   1 
ATOM   9136  C  CA  . PRO B 1 301 ? 116.586 167.247 149.311 1.00 73.73  ? 301  PRO B CA  1 
ATOM   9137  C  C   . PRO B 1 301 ? 116.471 168.519 148.488 1.00 73.73  ? 301  PRO B C   1 
ATOM   9138  O  O   . PRO B 1 301 ? 115.900 168.491 147.392 1.00 73.73  ? 301  PRO B O   1 
ATOM   9139  C  CB  . PRO B 1 301 ? 115.463 167.127 150.349 1.00 73.73  ? 301  PRO B CB  1 
ATOM   9140  C  CG  . PRO B 1 301 ? 116.077 166.408 151.483 1.00 73.73  ? 301  PRO B CG  1 
ATOM   9141  C  CD  . PRO B 1 301 ? 117.485 166.908 151.547 1.00 73.73  ? 301  PRO B CD  1 
ATOM   9142  N  N   . VAL B 1 302 ? 116.992 169.642 148.987 1.00 73.51  ? 302  VAL B N   1 
ATOM   9143  C  CA  . VAL B 1 302 ? 116.962 170.878 148.209 1.00 73.51  ? 302  VAL B CA  1 
ATOM   9144  C  C   . VAL B 1 302 ? 117.809 170.735 146.950 1.00 73.51  ? 302  VAL B C   1 
ATOM   9145  O  O   . VAL B 1 302 ? 117.401 171.150 145.857 1.00 73.51  ? 302  VAL B O   1 
ATOM   9146  C  CB  . VAL B 1 302 ? 117.423 172.066 149.072 1.00 73.51  ? 302  VAL B CB  1 
ATOM   9147  C  CG1 . VAL B 1 302 ? 117.469 173.340 148.243 1.00 73.51  ? 302  VAL B CG1 1 
ATOM   9148  C  CG2 . VAL B 1 302 ? 116.504 172.236 150.271 1.00 73.51  ? 302  VAL B CG2 1 
ATOM   9149  N  N   . VAL B 1 303 ? 119.000 170.145 147.084 1.00 73.47  ? 303  VAL B N   1 
ATOM   9150  C  CA  . VAL B 1 303 ? 119.860 169.906 145.925 1.00 73.47  ? 303  VAL B CA  1 
ATOM   9151  C  C   . VAL B 1 303 ? 119.163 168.976 144.941 1.00 73.47  ? 303  VAL B C   1 
ATOM   9152  O  O   . VAL B 1 303 ? 119.179 169.195 143.723 1.00 73.47  ? 303  VAL B O   1 
ATOM   9153  C  CB  . VAL B 1 303 ? 121.216 169.331 146.369 1.00 73.47  ? 303  VAL B CB  1 
ATOM   9154  C  CG1 . VAL B 1 303 ? 122.095 169.044 145.160 1.00 73.47  ? 303  VAL B CG1 1 
ATOM   9155  C  CG2 . VAL B 1 303 ? 121.909 170.285 147.325 1.00 73.47  ? 303  VAL B CG2 1 
ATOM   9156  N  N   . LEU B 1 304 ? 118.548 167.913 145.466 1.00 75.43  ? 304  LEU B N   1 
ATOM   9157  C  CA  . LEU B 1 304 ? 117.792 166.985 144.632 1.00 75.43  ? 304  LEU B CA  1 
ATOM   9158  C  C   . LEU B 1 304 ? 116.706 167.703 143.839 1.00 75.43  ? 304  LEU B C   1 
ATOM   9159  O  O   . LEU B 1 304 ? 116.583 167.524 142.623 1.00 75.43  ? 304  LEU B O   1 
ATOM   9160  C  CB  . LEU B 1 304 ? 117.181 165.886 145.508 1.00 75.43  ? 304  LEU B CB  1 
ATOM   9161  C  CG  . LEU B 1 304 ? 116.089 165.017 144.876 1.00 75.43  ? 304  LEU B CG  1 
ATOM   9162  C  CD1 . LEU B 1 304 ? 116.565 164.363 143.592 1.00 75.43  ? 304  LEU B CD1 1 
ATOM   9163  C  CD2 . LEU B 1 304 ? 115.607 163.967 145.865 1.00 75.43  ? 304  LEU B CD2 1 
ATOM   9164  N  N   . LEU B 1 305 ? 115.912 168.526 144.526 1.00 82.43  ? 305  LEU B N   1 
ATOM   9165  C  CA  . LEU B 1 305 ? 114.819 169.242 143.879 1.00 82.43  ? 305  LEU B CA  1 
ATOM   9166  C  C   . LEU B 1 305 ? 115.341 170.184 142.802 1.00 82.43  ? 305  LEU B C   1 
ATOM   9167  O  O   . LEU B 1 305 ? 114.811 170.229 141.687 1.00 82.43  ? 305  LEU B O   1 
ATOM   9168  C  CB  . LEU B 1 305 ? 114.013 170.011 144.927 1.00 82.43  ? 305  LEU B CB  1 
ATOM   9169  C  CG  . LEU B 1 305 ? 112.788 170.771 144.417 1.00 82.43  ? 305  LEU B CG  1 
ATOM   9170  C  CD1 . LEU B 1 305 ? 111.768 169.810 143.830 1.00 82.43  ? 305  LEU B CD1 1 
ATOM   9171  C  CD2 . LEU B 1 305 ? 112.169 171.604 145.528 1.00 82.43  ? 305  LEU B CD2 1 
ATOM   9172  N  N   . ILE B 1 306 ? 116.396 170.940 143.121 1.00 79.97  ? 306  ILE B N   1 
ATOM   9173  C  CA  . ILE B 1 306 ? 116.933 171.914 142.170 1.00 79.97  ? 306  ILE B CA  1 
ATOM   9174  C  C   . ILE B 1 306 ? 117.443 171.206 140.920 1.00 79.97  ? 306  ILE B C   1 
ATOM   9175  O  O   . ILE B 1 306 ? 117.126 171.592 139.787 1.00 79.97  ? 306  ILE B O   1 
ATOM   9176  C  CB  . ILE B 1 306 ? 118.040 172.756 142.825 1.00 79.97  ? 306  ILE B CB  1 
ATOM   9177  C  CG1 . ILE B 1 306 ? 117.439 173.750 143.820 1.00 79.97  ? 306  ILE B CG1 1 
ATOM   9178  C  CG2 . ILE B 1 306 ? 118.853 173.485 141.766 1.00 79.97  ? 306  ILE B CG2 1 
ATOM   9179  C  CD1 . ILE B 1 306 ? 118.446 174.727 144.390 1.00 79.97  ? 306  ILE B CD1 1 
ATOM   9180  N  N   . ASN B 1 307 ? 118.233 170.147 141.112 1.00 80.31  ? 307  ASN B N   1 
ATOM   9181  C  CA  . ASN B 1 307 ? 118.816 169.452 139.970 1.00 80.31  ? 307  ASN B CA  1 
ATOM   9182  C  C   . ASN B 1 307 ? 117.745 168.753 139.140 1.00 80.31  ? 307  ASN B C   1 
ATOM   9183  O  O   . ASN B 1 307 ? 117.804 168.756 137.906 1.00 80.31  ? 307  ASN B O   1 
ATOM   9184  C  CB  . ASN B 1 307 ? 119.876 168.460 140.445 1.00 80.31  ? 307  ASN B CB  1 
ATOM   9185  C  CG  . ASN B 1 307 ? 121.151 169.145 140.887 1.00 80.31  ? 307  ASN B CG  1 
ATOM   9186  O  OD1 . ASN B 1 307 ? 121.218 170.372 140.954 1.00 80.31  ? 307  ASN B OD1 1 
ATOM   9187  N  ND2 . ASN B 1 307 ? 122.173 168.356 141.185 1.00 80.31  ? 307  ASN B ND2 1 
ATOM   9188  N  N   . GLY B 1 308 ? 116.755 168.146 139.798 1.00 85.13  ? 308  GLY B N   1 
ATOM   9189  C  CA  . GLY B 1 308 ? 115.685 167.502 139.054 1.00 85.13  ? 308  GLY B CA  1 
ATOM   9190  C  C   . GLY B 1 308 ? 114.857 168.492 138.259 1.00 85.13  ? 308  GLY B C   1 
ATOM   9191  O  O   . GLY B 1 308 ? 114.463 168.222 137.122 1.00 85.13  ? 308  GLY B O   1 
ATOM   9192  N  N   . TYR B 1 309 ? 114.580 169.657 138.850 1.00 85.88  ? 309  TYR B N   1 
ATOM   9193  C  CA  . TYR B 1 309 ? 113.780 170.662 138.162 1.00 85.88  ? 309  TYR B CA  1 
ATOM   9194  C  C   . TYR B 1 309 ? 114.541 171.267 136.990 1.00 85.88  ? 309  TYR B C   1 
ATOM   9195  O  O   . TYR B 1 309 ? 113.956 171.540 135.935 1.00 85.88  ? 309  TYR B O   1 
ATOM   9196  C  CB  . TYR B 1 309 ? 113.355 171.747 139.152 1.00 85.88  ? 309  TYR B CB  1 
ATOM   9197  C  CG  . TYR B 1 309 ? 112.138 172.541 138.735 1.00 85.88  ? 309  TYR B CG  1 
ATOM   9198  C  CD1 . TYR B 1 309 ? 112.211 173.489 137.723 1.00 85.88  ? 309  TYR B CD1 1 
ATOM   9199  C  CD2 . TYR B 1 309 ? 110.913 172.342 139.358 1.00 85.88  ? 309  TYR B CD2 1 
ATOM   9200  C  CE1 . TYR B 1 309 ? 111.098 174.215 137.343 1.00 85.88  ? 309  TYR B CE1 1 
ATOM   9201  C  CE2 . TYR B 1 309 ? 109.796 173.062 138.985 1.00 85.88  ? 309  TYR B CE2 1 
ATOM   9202  C  CZ  . TYR B 1 309 ? 109.893 173.997 137.978 1.00 85.88  ? 309  TYR B CZ  1 
ATOM   9203  O  OH  . TYR B 1 309 ? 108.781 174.716 137.605 1.00 85.88  ? 309  TYR B OH  1 
ATOM   9204  N  N   . THR B 1 310 ? 115.847 171.484 137.151 1.00 86.20  ? 310  THR B N   1 
ATOM   9205  C  CA  . THR B 1 310 ? 116.621 172.177 136.127 1.00 86.20  ? 310  THR B CA  1 
ATOM   9206  C  C   . THR B 1 310 ? 117.313 171.222 135.161 1.00 86.20  ? 310  THR B C   1 
ATOM   9207  O  O   . THR B 1 310 ? 117.090 171.291 133.948 1.00 86.20  ? 310  THR B O   1 
ATOM   9208  C  CB  . THR B 1 310 ? 117.661 173.089 136.779 1.00 86.20  ? 310  THR B CB  1 
ATOM   9209  O  OG1 . THR B 1 310 ? 117.013 173.967 137.708 1.00 86.20  ? 310  THR B OG1 1 
ATOM   9210  C  CG2 . THR B 1 310 ? 118.378 173.916 135.723 1.00 86.20  ? 310  THR B CG2 1 
ATOM   9211  N  N   . LYS B 1 311 ? 118.159 170.334 135.687 1.00 84.96  ? 311  LYS B N   1 
ATOM   9212  C  CA  . LYS B 1 311 ? 119.033 169.523 134.847 1.00 84.96  ? 311  LYS B CA  1 
ATOM   9213  C  C   . LYS B 1 311 ? 118.273 168.549 133.952 1.00 84.96  ? 311  LYS B C   1 
ATOM   9214  O  O   . LYS B 1 311 ? 118.619 168.368 132.780 1.00 84.96  ? 311  LYS B O   1 
ATOM   9215  C  CB  . LYS B 1 311 ? 120.032 168.762 135.723 1.00 84.96  ? 311  LYS B CB  1 
ATOM   9216  C  CG  . LYS B 1 311 ? 121.269 169.558 136.071 1.00 84.96  ? 311  LYS B CG  1 
ATOM   9217  C  CD  . LYS B 1 311 ? 122.186 169.661 134.870 1.00 84.96  ? 311  LYS B CD  1 
ATOM   9218  C  CE  . LYS B 1 311 ? 122.546 168.285 134.334 1.00 84.96  ? 311  LYS B CE  1 
ATOM   9219  N  NZ  . LYS B 1 311 ? 123.230 168.361 133.014 1.00 84.96  ? 311  LYS B NZ  1 
ATOM   9220  N  N   . GLY B 1 312 ? 117.234 167.912 134.485 1.00 86.51  ? 312  GLY B N   1 
ATOM   9221  C  CA  . GLY B 1 312 ? 116.620 166.821 133.756 1.00 86.51  ? 312  GLY B CA  1 
ATOM   9222  C  C   . GLY B 1 312 ? 116.499 165.548 134.567 1.00 86.51  ? 312  GLY B C   1 
ATOM   9223  O  O   . GLY B 1 312 ? 115.686 165.478 135.494 1.00 86.51  ? 312  GLY B O   1 
ATOM   9224  N  N   . ASP B 1 313 ? 117.285 164.530 134.202 1.00 83.27  ? 313  ASP B N   1 
ATOM   9225  C  CA  . ASP B 1 313 ? 117.235 163.205 134.814 1.00 83.27  ? 313  ASP B CA  1 
ATOM   9226  C  C   . ASP B 1 313 ? 117.165 163.281 136.334 1.00 83.27  ? 313  ASP B C   1 
ATOM   9227  O  O   . ASP B 1 313 ? 118.066 163.820 136.985 1.00 83.27  ? 313  ASP B O   1 
ATOM   9228  C  CB  . ASP B 1 313 ? 118.456 162.383 134.389 1.00 83.27  ? 313  ASP B CB  1 
ATOM   9229  C  CG  . ASP B 1 313 ? 118.412 160.951 134.899 1.00 83.27  ? 313  ASP B CG  1 
ATOM   9230  O  OD1 . ASP B 1 313 ? 117.385 160.546 135.485 1.00 83.27  ? 313  ASP B OD1 1 
ATOM   9231  O  OD2 . ASP B 1 313 ? 119.414 160.228 134.716 1.00 83.27  ? 313  ASP B OD2 1 
ATOM   9232  N  N   . TRP B 1 314 ? 116.088 162.735 136.902 1.00 81.26  ? 314  TRP B N   1 
ATOM   9233  C  CA  . TRP B 1 314 ? 115.878 162.815 138.343 1.00 81.26  ? 314  TRP B CA  1 
ATOM   9234  C  C   . TRP B 1 314 ? 116.759 161.821 139.087 1.00 81.26  ? 314  TRP B C   1 
ATOM   9235  O  O   . TRP B 1 314 ? 117.214 162.092 140.204 1.00 81.26  ? 314  TRP B O   1 
ATOM   9236  C  CB  . TRP B 1 314 ? 114.403 162.574 138.662 1.00 81.26  ? 314  TRP B CB  1 
ATOM   9237  C  CG  . TRP B 1 314 ? 113.554 163.795 138.510 1.00 81.26  ? 314  TRP B CG  1 
ATOM   9238  C  CD1 . TRP B 1 314 ? 112.807 164.144 137.424 1.00 81.26  ? 314  TRP B CD1 1 
ATOM   9239  C  CD2 . TRP B 1 314 ? 113.355 164.827 139.482 1.00 81.26  ? 314  TRP B CD2 1 
ATOM   9240  N  NE1 . TRP B 1 314 ? 112.160 165.333 137.656 1.00 81.26  ? 314  TRP B NE1 1 
ATOM   9241  C  CE2 . TRP B 1 314 ? 112.479 165.772 138.914 1.00 81.26  ? 314  TRP B CE2 1 
ATOM   9242  C  CE3 . TRP B 1 314 ? 113.833 165.044 140.778 1.00 81.26  ? 314  TRP B CE3 1 
ATOM   9243  C  CZ2 . TRP B 1 314 ? 112.072 166.916 139.595 1.00 81.26  ? 314  TRP B CZ2 1 
ATOM   9244  C  CZ3 . TRP B 1 314 ? 113.428 166.180 141.452 1.00 81.26  ? 314  TRP B CZ3 1 
ATOM   9245  C  CH2 . TRP B 1 314 ? 112.556 167.102 140.860 1.00 81.26  ? 314  TRP B CH2 1 
ATOM   9246  N  N   . TRP B 1 315 ? 117.000 160.653 138.489 1.00 80.73  ? 315  TRP B N   1 
ATOM   9247  C  CA  . TRP B 1 315 ? 117.753 159.606 139.173 1.00 80.73  ? 315  TRP B CA  1 
ATOM   9248  C  C   . TRP B 1 315 ? 119.198 160.028 139.408 1.00 80.73  ? 315  TRP B C   1 
ATOM   9249  O  O   . TRP B 1 315 ? 119.744 159.846 140.502 1.00 80.73  ? 315  TRP B O   1 
ATOM   9250  C  CB  . TRP B 1 315 ? 117.689 158.307 138.369 1.00 80.73  ? 315  TRP B CB  1 
ATOM   9251  C  CG  . TRP B 1 315 ? 116.401 157.556 138.543 1.00 80.73  ? 315  TRP B CG  1 
ATOM   9252  C  CD1 . TRP B 1 315 ? 115.599 157.072 137.551 1.00 80.73  ? 315  TRP B CD1 1 
ATOM   9253  C  CD2 . TRP B 1 315 ? 115.765 157.201 139.780 1.00 80.73  ? 315  TRP B CD2 1 
ATOM   9254  N  NE1 . TRP B 1 315 ? 114.505 156.441 138.090 1.00 80.73  ? 315  TRP B NE1 1 
ATOM   9255  C  CE2 . TRP B 1 315 ? 114.583 156.506 139.456 1.00 80.73  ? 315  TRP B CE2 1 
ATOM   9256  C  CE3 . TRP B 1 315 ? 116.080 157.402 141.128 1.00 80.73  ? 315  TRP B CE3 1 
ATOM   9257  C  CZ2 . TRP B 1 315 ? 113.717 156.013 140.429 1.00 80.73  ? 315  TRP B CZ2 1 
ATOM   9258  C  CZ3 . TRP B 1 315 ? 115.218 156.913 142.091 1.00 80.73  ? 315  TRP B CZ3 1 
ATOM   9259  C  CH2 . TRP B 1 315 ? 114.051 156.226 141.737 1.00 80.73  ? 315  TRP B CH2 1 
ATOM   9260  N  N   . GLU B 1 316 ? 119.835 160.598 138.384 1.00 78.68  ? 316  GLU B N   1 
ATOM   9261  C  CA  . GLU B 1 316 ? 121.200 161.083 138.550 1.00 78.68  ? 316  GLU B CA  1 
ATOM   9262  C  C   . GLU B 1 316 ? 121.247 162.233 139.546 1.00 78.68  ? 316  GLU B C   1 
ATOM   9263  O  O   . GLU B 1 316 ? 122.211 162.376 140.303 1.00 78.68  ? 316  GLU B O   1 
ATOM   9264  C  CB  . GLU B 1 316 ? 121.782 161.509 137.202 1.00 78.68  ? 316  GLU B CB  1 
ATOM   9265  C  CG  . GLU B 1 316 ? 123.292 161.357 137.119 1.00 78.68  ? 316  GLU B CG  1 
ATOM   9266  C  CD  . GLU B 1 316 ? 123.792 161.234 135.695 1.00 78.68  ? 316  GLU B CD  1 
ATOM   9267  O  OE1 . GLU B 1 316 ? 122.967 161.330 134.763 1.00 78.68  ? 316  GLU B OE1 1 
ATOM   9268  O  OE2 . GLU B 1 316 ? 125.012 161.042 135.509 1.00 78.68  ? 316  GLU B OE2 1 
ATOM   9269  N  N   . ALA B 1 317 ? 120.205 163.067 139.557 1.00 77.83  ? 317  ALA B N   1 
ATOM   9270  C  CA  . ALA B 1 317 ? 120.139 164.153 140.529 1.00 77.83  ? 317  ALA B CA  1 
ATOM   9271  C  C   . ALA B 1 317 ? 120.080 163.618 141.954 1.00 77.83  ? 317  ALA B C   1 
ATOM   9272  O  O   . ALA B 1 317 ? 120.773 164.122 142.846 1.00 77.83  ? 317  ALA B O   1 
ATOM   9273  C  CB  . ALA B 1 317 ? 118.927 165.038 140.239 1.00 77.83  ? 317  ALA B CB  1 
ATOM   9274  N  N   . ALA B 1 318 ? 119.255 162.594 142.186 1.00 75.73  ? 318  ALA B N   1 
ATOM   9275  C  CA  . ALA B 1 318 ? 119.174 161.990 143.512 1.00 75.73  ? 318  ALA B CA  1 
ATOM   9276  C  C   . ALA B 1 318 ? 120.488 161.327 143.893 1.00 75.73  ? 318  ALA B C   1 
ATOM   9277  O  O   . ALA B 1 318 ? 120.925 161.412 145.046 1.00 75.73  ? 318  ALA B O   1 
ATOM   9278  C  CB  . ALA B 1 318 ? 118.027 160.982 143.563 1.00 75.73  ? 318  ALA B CB  1 
ATOM   9279  N  N   . LEU B 1 319 ? 121.130 160.657 142.935 1.00 74.13  ? 319  LEU B N   1 
ATOM   9280  C  CA  . LEU B 1 319 ? 122.427 160.045 143.198 1.00 74.13  ? 319  LEU B CA  1 
ATOM   9281  C  C   . LEU B 1 319 ? 123.456 161.097 143.589 1.00 74.13  ? 319  LEU B C   1 
ATOM   9282  O  O   . LEU B 1 319 ? 124.231 160.902 144.531 1.00 74.13  ? 319  LEU B O   1 
ATOM   9283  C  CB  . LEU B 1 319 ? 122.885 159.274 141.961 1.00 74.13  ? 319  LEU B CB  1 
ATOM   9284  C  CG  . LEU B 1 319 ? 124.091 158.339 142.020 1.00 74.13  ? 319  LEU B CG  1 
ATOM   9285  C  CD1 . LEU B 1 319 ? 123.929 157.293 140.949 1.00 74.13  ? 319  LEU B CD1 1 
ATOM   9286  C  CD2 . LEU B 1 319 ? 125.392 159.077 141.816 1.00 74.13  ? 319  LEU B CD2 1 
ATOM   9287  N  N   . PHE B 1 320 ? 123.472 162.222 142.874 1.00 73.38  ? 320  PHE B N   1 
ATOM   9288  C  CA  . PHE B 1 320 ? 124.416 163.298 143.160 1.00 73.38  ? 320  PHE B CA  1 
ATOM   9289  C  C   . PHE B 1 320 ? 124.148 163.921 144.526 1.00 73.38  ? 320  PHE B C   1 
ATOM   9290  O  O   . PHE B 1 320 ? 125.085 164.203 145.288 1.00 73.38  ? 320  PHE B O   1 
ATOM   9291  C  CB  . PHE B 1 320 ? 124.321 164.337 142.043 1.00 73.38  ? 320  PHE B CB  1 
ATOM   9292  C  CG  . PHE B 1 320 ? 125.143 165.565 142.268 1.00 73.38  ? 320  PHE B CG  1 
ATOM   9293  C  CD1 . PHE B 1 320 ? 126.522 165.520 142.188 1.00 73.38  ? 320  PHE B CD1 1 
ATOM   9294  C  CD2 . PHE B 1 320 ? 124.532 166.776 142.527 1.00 73.38  ? 320  PHE B CD2 1 
ATOM   9295  C  CE1 . PHE B 1 320 ? 127.273 166.660 142.377 1.00 73.38  ? 320  PHE B CE1 1 
ATOM   9296  C  CE2 . PHE B 1 320 ? 125.276 167.913 142.715 1.00 73.38  ? 320  PHE B CE2 1 
ATOM   9297  C  CZ  . PHE B 1 320 ? 126.650 167.856 142.644 1.00 73.38  ? 320  PHE B CZ  1 
ATOM   9298  N  N   . ALA B 1 321 ? 122.872 164.143 144.853 1.00 72.61  ? 321  ALA B N   1 
ATOM   9299  C  CA  . ALA B 1 321 ? 122.524 164.688 146.161 1.00 72.61  ? 321  ALA B CA  1 
ATOM   9300  C  C   . ALA B 1 321 ? 122.928 163.737 147.279 1.00 72.61  ? 321  ALA B C   1 
ATOM   9301  O  O   . ALA B 1 321 ? 123.469 164.166 148.305 1.00 72.61  ? 321  ALA B O   1 
ATOM   9302  C  CB  . ALA B 1 321 ? 121.026 164.986 146.224 1.00 72.61  ? 321  ALA B CB  1 
ATOM   9303  N  N   . LEU B 1 322 ? 122.683 162.439 147.098 1.00 71.45  ? 322  LEU B N   1 
ATOM   9304  C  CA  . LEU B 1 322 ? 123.102 161.471 148.105 1.00 71.45  ? 322  LEU B CA  1 
ATOM   9305  C  C   . LEU B 1 322 ? 124.619 161.433 148.227 1.00 71.45  ? 322  LEU B C   1 
ATOM   9306  O  O   . LEU B 1 322 ? 125.156 161.309 149.332 1.00 71.45  ? 322  LEU B O   1 
ATOM   9307  C  CB  . LEU B 1 322 ? 122.556 160.086 147.766 1.00 71.45  ? 322  LEU B CB  1 
ATOM   9308  C  CG  . LEU B 1 322 ? 122.683 159.052 148.884 1.00 71.45  ? 322  LEU B CG  1 
ATOM   9309  C  CD1 . LEU B 1 322 ? 122.022 159.560 150.154 1.00 71.45  ? 322  LEU B CD1 1 
ATOM   9310  C  CD2 . LEU B 1 322 ? 122.084 157.726 148.457 1.00 71.45  ? 322  LEU B CD2 1 
ATOM   9311  N  N   . SER B 1 323 ? 125.327 161.545 147.101 1.00 70.41  ? 323  SER B N   1 
ATOM   9312  C  CA  . SER B 1 323 ? 126.784 161.517 147.137 1.00 70.41  ? 323  SER B CA  1 
ATOM   9313  C  C   . SER B 1 323 ? 127.345 162.705 147.905 1.00 70.41  ? 323  SER B C   1 
ATOM   9314  O  O   . SER B 1 323 ? 128.276 162.548 148.704 1.00 70.41  ? 323  SER B O   1 
ATOM   9315  C  CB  . SER B 1 323 ? 127.342 161.486 145.715 1.00 70.41  ? 323  SER B CB  1 
ATOM   9316  O  OG  . SER B 1 323 ? 128.750 161.640 145.720 1.00 70.41  ? 323  SER B OG  1 
ATOM   9317  N  N   . VAL B 1 324 ? 126.800 163.903 147.681 1.00 69.93  ? 324  VAL B N   1 
ATOM   9318  C  CA  . VAL B 1 324 ? 127.290 165.049 148.444 1.00 69.93  ? 324  VAL B CA  1 
ATOM   9319  C  C   . VAL B 1 324 ? 126.857 164.949 149.904 1.00 69.93  ? 324  VAL B C   1 
ATOM   9320  O  O   . VAL B 1 324 ? 127.578 165.400 150.801 1.00 69.93  ? 324  VAL B O   1 
ATOM   9321  C  CB  . VAL B 1 324 ? 126.852 166.385 147.812 1.00 69.93  ? 324  VAL B CB  1 
ATOM   9322  C  CG1 . VAL B 1 324 ? 127.529 166.583 146.468 1.00 69.93  ? 324  VAL B CG1 1 
ATOM   9323  C  CG2 . VAL B 1 324 ? 125.348 166.469 147.675 1.00 69.93  ? 324  VAL B CG2 1 
ATOM   9324  N  N   . ALA B 1 325 ? 125.690 164.354 150.174 1.00 68.77  ? 325  ALA B N   1 
ATOM   9325  C  CA  . ALA B 1 325 ? 125.236 164.219 151.555 1.00 68.77  ? 325  ALA B CA  1 
ATOM   9326  C  C   . ALA B 1 325 ? 126.044 163.172 152.313 1.00 68.77  ? 325  ALA B C   1 
ATOM   9327  O  O   . ALA B 1 325 ? 126.082 163.185 153.549 1.00 68.77  ? 325  ALA B O   1 
ATOM   9328  C  CB  . ALA B 1 325 ? 123.749 163.871 151.583 1.00 68.77  ? 325  ALA B CB  1 
ATOM   9329  N  N   . VAL B 1 326 ? 126.682 162.250 151.591 1.00 64.64  ? 326  VAL B N   1 
ATOM   9330  C  CA  . VAL B 1 326 ? 127.514 161.214 152.198 1.00 64.64  ? 326  VAL B CA  1 
ATOM   9331  C  C   . VAL B 1 326 ? 128.639 161.861 152.996 1.00 64.64  ? 326  VAL B C   1 
ATOM   9332  O  O   . VAL B 1 326 ? 129.093 161.313 154.008 1.00 64.64  ? 326  VAL B O   1 
ATOM   9333  C  CB  . VAL B 1 326 ? 128.058 160.249 151.127 1.00 64.64  ? 326  VAL B CB  1 
ATOM   9334  C  CG1 . VAL B 1 326 ? 129.296 159.516 151.617 1.00 64.64  ? 326  VAL B CG1 1 
ATOM   9335  C  CG2 . VAL B 1 326 ? 126.992 159.243 150.752 1.00 64.64  ? 326  VAL B CG2 1 
ATOM   9336  N  N   . GLY B 1 327 ? 129.076 163.045 152.564 1.00 66.05  ? 327  GLY B N   1 
ATOM   9337  C  CA  . GLY B 1 327 ? 130.100 163.754 153.312 1.00 66.05  ? 327  GLY B CA  1 
ATOM   9338  C  C   . GLY B 1 327 ? 129.696 164.015 154.751 1.00 66.05  ? 327  GLY B C   1 
ATOM   9339  O  O   . GLY B 1 327 ? 130.517 163.906 155.665 1.00 66.05  ? 327  GLY B O   1 
ATOM   9340  N  N   . LEU B 1 328 ? 128.426 164.351 154.974 1.00 65.20  ? 328  LEU B N   1 
ATOM   9341  C  CA  . LEU B 1 328 ? 127.907 164.602 156.313 1.00 65.20  ? 328  LEU B CA  1 
ATOM   9342  C  C   . LEU B 1 328 ? 127.196 163.391 156.904 1.00 65.20  ? 328  LEU B C   1 
ATOM   9343  O  O   . LEU B 1 328 ? 126.222 163.556 157.651 1.00 65.20  ? 328  LEU B O   1 
ATOM   9344  C  CB  . LEU B 1 328 ? 126.971 165.811 156.293 1.00 65.20  ? 328  LEU B CB  1 
ATOM   9345  C  CG  . LEU B 1 328 ? 127.630 167.171 156.066 1.00 65.20  ? 328  LEU B CG  1 
ATOM   9346  C  CD1 . LEU B 1 328 ? 126.587 168.276 156.057 1.00 65.20  ? 328  LEU B CD1 1 
ATOM   9347  C  CD2 . LEU B 1 328 ? 128.679 167.431 157.132 1.00 65.20  ? 328  LEU B CD2 1 
ATOM   9348  N  N   . THR B 1 329 ? 127.646 162.182 156.586 1.00 66.57  ? 329  THR B N   1 
ATOM   9349  C  CA  . THR B 1 329 ? 126.989 160.995 157.108 1.00 66.57  ? 329  THR B CA  1 
ATOM   9350  C  C   . THR B 1 329 ? 127.197 160.901 158.619 1.00 66.57  ? 329  THR B C   1 
ATOM   9351  O  O   . THR B 1 329 ? 128.253 161.295 159.129 1.00 66.57  ? 329  THR B O   1 
ATOM   9352  C  CB  . THR B 1 329 ? 127.517 159.731 156.424 1.00 66.57  ? 329  THR B CB  1 
ATOM   9353  O  OG1 . THR B 1 329 ? 126.817 158.587 156.928 1.00 66.57  ? 329  THR B OG1 1 
ATOM   9354  C  CG2 . THR B 1 329 ? 129.009 159.557 156.675 1.00 66.57  ? 329  THR B CG2 1 
ATOM   9355  N  N   . PRO B 1 330 ? 126.206 160.412 159.367 1.00 60.97  ? 330  PRO B N   1 
ATOM   9356  C  CA  . PRO B 1 330 ? 126.371 160.254 160.815 1.00 60.97  ? 330  PRO B CA  1 
ATOM   9357  C  C   . PRO B 1 330 ? 127.028 158.949 161.235 1.00 60.97  ? 330  PRO B C   1 
ATOM   9358  O  O   . PRO B 1 330 ? 127.342 158.793 162.420 1.00 60.97  ? 330  PRO B O   1 
ATOM   9359  C  CB  . PRO B 1 330 ? 124.926 160.321 161.321 1.00 60.97  ? 330  PRO B CB  1 
ATOM   9360  C  CG  . PRO B 1 330 ? 124.143 159.715 160.212 1.00 60.97  ? 330  PRO B CG  1 
ATOM   9361  C  CD  . PRO B 1 330 ? 124.814 160.182 158.945 1.00 60.97  ? 330  PRO B CD  1 
ATOM   9362  N  N   . GLU B 1 331 ? 127.251 158.011 160.314 1.00 64.39  ? 331  GLU B N   1 
ATOM   9363  C  CA  . GLU B 1 331 ? 127.829 156.719 160.658 1.00 64.39  ? 331  GLU B CA  1 
ATOM   9364  C  C   . GLU B 1 331 ? 129.353 156.741 160.640 1.00 64.39  ? 331  GLU B C   1 
ATOM   9365  O  O   . GLU B 1 331 ? 129.987 155.704 160.861 1.00 64.39  ? 331  GLU B O   1 
ATOM   9366  C  CB  . GLU B 1 331 ? 127.301 155.627 159.727 1.00 64.39  ? 331  GLU B CB  1 
ATOM   9367  C  CG  . GLU B 1 331 ? 127.300 154.250 160.375 1.00 64.39  ? 331  GLU B CG  1 
ATOM   9368  C  CD  . GLU B 1 331 ? 126.309 153.297 159.750 1.00 64.39  ? 331  GLU B CD  1 
ATOM   9369  O  OE1 . GLU B 1 331 ? 125.115 153.654 159.657 1.00 64.39  ? 331  GLU B OE1 1 
ATOM   9370  O  OE2 . GLU B 1 331 ? 126.724 152.184 159.365 1.00 64.39  ? 331  GLU B OE2 1 
ATOM   9371  N  N   . MET B 1 332 ? 129.954 157.895 160.373 1.00 57.87  ? 332  MET B N   1 
ATOM   9372  C  CA  . MET B 1 332 ? 131.381 158.053 160.597 1.00 57.87  ? 332  MET B CA  1 
ATOM   9373  C  C   . MET B 1 332 ? 131.729 158.136 162.077 1.00 57.87  ? 332  MET B C   1 
ATOM   9374  O  O   . MET B 1 332 ? 132.846 157.770 162.458 1.00 57.87  ? 332  MET B O   1 
ATOM   9375  C  CB  . MET B 1 332 ? 131.895 159.297 159.865 1.00 57.87  ? 332  MET B CB  1 
ATOM   9376  C  CG  . MET B 1 332 ? 131.344 160.606 160.401 1.00 57.87  ? 332  MET B CG  1 
ATOM   9377  S  SD  . MET B 1 332 ? 131.897 162.037 159.458 1.00 57.87  ? 332  MET B SD  1 
ATOM   9378  C  CE  . MET B 1 332 ? 131.139 163.364 160.390 1.00 57.87  ? 332  MET B CE  1 
ATOM   9379  N  N   . LEU B 1 333 ? 130.790 158.583 162.915 1.00 48.76  ? 333  LEU B N   1 
ATOM   9380  C  CA  . LEU B 1 333 ? 131.050 158.698 164.350 1.00 48.76  ? 333  LEU B CA  1 
ATOM   9381  C  C   . LEU B 1 333 ? 131.426 157.375 165.007 1.00 48.76  ? 333  LEU B C   1 
ATOM   9382  O  O   . LEU B 1 333 ? 132.349 157.372 165.840 1.00 48.76  ? 333  LEU B O   1 
ATOM   9383  C  CB  . LEU B 1 333 ? 129.843 159.336 165.048 1.00 48.76  ? 333  LEU B CB  1 
ATOM   9384  C  CG  . LEU B 1 333 ? 129.705 160.863 165.052 1.00 48.76  ? 333  LEU B CG  1 
ATOM   9385  C  CD1 . LEU B 1 333 ? 130.853 161.499 165.820 1.00 48.76  ? 333  LEU B CD1 1 
ATOM   9386  C  CD2 . LEU B 1 333 ? 129.606 161.443 163.651 1.00 48.76  ? 333  LEU B CD2 1 
ATOM   9387  N  N   . PRO B 1 334 ? 130.764 156.230 164.718 1.00 50.50  ? 334  PRO B N   1 
ATOM   9388  C  CA  . PRO B 1 334 ? 131.190 154.968 165.341 1.00 50.50  ? 334  PRO B CA  1 
ATOM   9389  C  C   . PRO B 1 334 ? 132.654 154.640 165.095 1.00 50.50  ? 334  PRO B C   1 
ATOM   9390  O  O   . PRO B 1 334 ? 133.312 154.050 165.956 1.00 50.50  ? 334  PRO B O   1 
ATOM   9391  C  CB  . PRO B 1 334 ? 130.267 153.933 164.691 1.00 50.50  ? 334  PRO B CB  1 
ATOM   9392  C  CG  . PRO B 1 334 ? 129.027 154.689 164.423 1.00 50.50  ? 334  PRO B CG  1 
ATOM   9393  C  CD  . PRO B 1 334 ? 129.480 156.064 164.009 1.00 50.50  ? 334  PRO B CD  1 
ATOM   9394  N  N   . MET B 1 335 ? 133.176 155.009 163.925 1.00 54.26  ? 335  MET B N   1 
ATOM   9395  C  CA  . MET B 1 335 ? 134.604 154.839 163.683 1.00 54.26  ? 335  MET B CA  1 
ATOM   9396  C  C   . MET B 1 335 ? 135.410 155.905 164.413 1.00 54.26  ? 335  MET B C   1 
ATOM   9397  O  O   . MET B 1 335 ? 136.307 155.583 165.202 1.00 54.26  ? 335  MET B O   1 
ATOM   9398  C  CB  . MET B 1 335 ? 134.901 154.878 162.184 1.00 54.26  ? 335  MET B CB  1 
ATOM   9399  C  CG  . MET B 1 335 ? 136.349 155.225 161.864 1.00 54.26  ? 335  MET B CG  1 
ATOM   9400  S  SD  . MET B 1 335 ? 136.700 155.323 160.100 1.00 54.26  ? 335  MET B SD  1 
ATOM   9401  C  CE  . MET B 1 335 ? 136.220 157.012 159.749 1.00 54.26  ? 335  MET B CE  1 
ATOM   9402  N  N   . ILE B 1 336 ? 135.071 157.182 164.188 1.00 45.71  ? 336  ILE B N   1 
ATOM   9403  C  CA  . ILE B 1 336 ? 135.882 158.302 164.671 1.00 45.71  ? 336  ILE B CA  1 
ATOM   9404  C  C   . ILE B 1 336 ? 136.213 158.127 166.146 1.00 45.71  ? 336  ILE B C   1 
ATOM   9405  O  O   . ILE B 1 336 ? 137.381 157.989 166.529 1.00 45.71  ? 336  ILE B O   1 
ATOM   9406  C  CB  . ILE B 1 336 ? 135.155 159.635 164.429 1.00 45.71  ? 336  ILE B CB  1 
ATOM   9407  C  CG1 . ILE B 1 336 ? 134.993 159.898 162.933 1.00 45.71  ? 336  ILE B CG1 1 
ATOM   9408  C  CG2 . ILE B 1 336 ? 135.887 160.775 165.120 1.00 45.71  ? 336  ILE B CG2 1 
ATOM   9409  C  CD1 . ILE B 1 336 ? 134.186 161.134 162.617 1.00 45.71  ? 336  ILE B CD1 1 
ATOM   9410  N  N   . VAL B 1 337 ? 135.175 158.090 166.985 1.00 42.70  ? 337  VAL B N   1 
ATOM   9411  C  CA  . VAL B 1 337 ? 135.369 157.881 168.417 1.00 42.70  ? 337  VAL B CA  1 
ATOM   9412  C  C   . VAL B 1 337 ? 136.254 156.667 168.650 1.00 42.70  ? 337  VAL B C   1 
ATOM   9413  O  O   . VAL B 1 337 ? 137.324 156.758 169.265 1.00 42.70  ? 337  VAL B O   1 
ATOM   9414  C  CB  . VAL B 1 337 ? 134.014 157.723 169.126 1.00 42.70  ? 337  VAL B CB  1 
ATOM   9415  C  CG1 . VAL B 1 337 ? 134.221 157.256 170.555 1.00 42.70  ? 337  VAL B CG1 1 
ATOM   9416  C  CG2 . VAL B 1 337 ? 133.235 159.024 169.081 1.00 42.70  ? 337  VAL B CG2 1 
ATOM   9417  N  N   . THR B 1 338 ? 135.841 155.521 168.107 1.00 45.44  ? 338  THR B N   1 
ATOM   9418  C  CA  . THR B 1 338 ? 136.590 154.292 168.325 1.00 45.44  ? 338  THR B CA  1 
ATOM   9419  C  C   . THR B 1 338 ? 138.008 154.421 167.788 1.00 45.44  ? 338  THR B C   1 
ATOM   9420  O  O   . THR B 1 338 ? 138.956 153.906 168.389 1.00 45.44  ? 338  THR B O   1 
ATOM   9421  C  CB  . THR B 1 338 ? 135.862 153.117 167.672 1.00 45.44  ? 338  THR B CB  1 
ATOM   9422  O  OG1 . THR B 1 338 ? 134.504 153.091 168.126 1.00 45.44  ? 338  THR B OG1 1 
ATOM   9423  C  CG2 . THR B 1 338 ? 136.511 151.812 168.060 1.00 45.44  ? 338  THR B CG2 1 
ATOM   9424  N  N   . SER B 1 339 ? 138.180 155.147 166.681 1.00 43.84  ? 339  SER B N   1 
ATOM   9425  C  CA  . SER B 1 339 ? 139.513 155.288 166.109 1.00 43.84  ? 339  SER B CA  1 
ATOM   9426  C  C   . SER B 1 339 ? 140.378 156.230 166.935 1.00 43.84  ? 339  SER B C   1 
ATOM   9427  O  O   . SER B 1 339 ? 141.607 156.112 166.926 1.00 43.84  ? 339  SER B O   1 
ATOM   9428  C  CB  . SER B 1 339 ? 139.423 155.781 164.665 1.00 43.84  ? 339  SER B CB  1 
ATOM   9429  O  OG  . SER B 1 339 ? 138.816 157.058 164.600 1.00 43.84  ? 339  SER B OG  1 
ATOM   9430  N  N   . THR B 1 340 ? 139.762 157.170 167.654 1.00 39.21  ? 340  THR B N   1 
ATOM   9431  C  CA  . THR B 1 340 ? 140.555 158.147 168.392 1.00 39.21  ? 340  THR B CA  1 
ATOM   9432  C  C   . THR B 1 340 ? 140.798 157.691 169.824 1.00 39.21  ? 340  THR B C   1 
ATOM   9433  O  O   . THR B 1 340 ? 141.948 157.487 170.235 1.00 39.21  ? 340  THR B O   1 
ATOM   9434  C  CB  . THR B 1 340 ? 139.868 159.511 168.373 1.00 39.21  ? 340  THR B CB  1 
ATOM   9435  O  OG1 . THR B 1 340 ? 139.416 159.799 167.045 1.00 39.21  ? 340  THR B OG1 1 
ATOM   9436  C  CG2 . THR B 1 340 ? 140.836 160.593 168.816 1.00 39.21  ? 340  THR B CG2 1 
ATOM   9437  N  N   . LEU B 1 341 ? 139.720 157.499 170.591 1.00 35.40  ? 341  LEU B N   1 
ATOM   9438  C  CA  . LEU B 1 341 ? 139.855 157.218 172.017 1.00 35.40  ? 341  LEU B CA  1 
ATOM   9439  C  C   . LEU B 1 341 ? 140.721 155.991 172.263 1.00 35.40  ? 341  LEU B C   1 
ATOM   9440  O  O   . LEU B 1 341 ? 141.640 156.033 173.090 1.00 35.40  ? 341  LEU B O   1 
ATOM   9441  C  CB  . LEU B 1 341 ? 138.475 157.035 172.646 1.00 35.40  ? 341  LEU B CB  1 
ATOM   9442  C  CG  . LEU B 1 341 ? 137.602 158.286 172.745 1.00 35.40  ? 341  LEU B CG  1 
ATOM   9443  C  CD1 . LEU B 1 341 ? 136.416 158.036 173.658 1.00 35.40  ? 341  LEU B CD1 1 
ATOM   9444  C  CD2 . LEU B 1 341 ? 138.417 159.467 173.237 1.00 35.40  ? 341  LEU B CD2 1 
ATOM   9445  N  N   . ALA B 1 342 ? 140.463 154.902 171.533 1.00 37.06  ? 342  ALA B N   1 
ATOM   9446  C  CA  . ALA B 1 342 ? 141.274 153.700 171.692 1.00 37.06  ? 342  ALA B CA  1 
ATOM   9447  C  C   . ALA B 1 342 ? 142.753 154.004 171.522 1.00 37.06  ? 342  ALA B C   1 
ATOM   9448  O  O   . ALA B 1 342 ? 143.571 153.544 172.328 1.00 37.06  ? 342  ALA B O   1 
ATOM   9449  C  CB  . ALA B 1 342 ? 140.835 152.627 170.697 1.00 37.06  ? 342  ALA B CB  1 
ATOM   9450  N  N   . ARG B 1 343 ? 143.108 154.805 170.512 1.00 38.39  ? 343  ARG B N   1 
ATOM   9451  C  CA  . ARG B 1 343 ? 144.499 155.208 170.344 1.00 38.39  ? 343  ARG B CA  1 
ATOM   9452  C  C   . ARG B 1 343 ? 145.034 155.822 171.629 1.00 38.39  ? 343  ARG B C   1 
ATOM   9453  O  O   . ARG B 1 343 ? 146.054 155.372 172.168 1.00 38.39  ? 343  ARG B O   1 
ATOM   9454  C  CB  . ARG B 1 343 ? 144.620 156.192 169.179 1.00 38.39  ? 343  ARG B CB  1 
ATOM   9455  C  CG  . ARG B 1 343 ? 145.926 156.980 169.126 1.00 38.39  ? 343  ARG B CG  1 
ATOM   9456  C  CD  . ARG B 1 343 ? 147.158 156.078 169.152 1.00 38.39  ? 343  ARG B CD  1 
ATOM   9457  N  NE  . ARG B 1 343 ? 148.391 156.817 168.900 1.00 38.39  ? 343  ARG B NE  1 
ATOM   9458  C  CZ  . ARG B 1 343 ? 148.909 157.728 169.712 1.00 38.39  ? 343  ARG B CZ  1 
ATOM   9459  N  NH1 . ARG B 1 343 ? 148.344 158.026 170.871 1.00 38.39  ? 343  ARG B NH1 1 
ATOM   9460  N  NH2 . ARG B 1 343 ? 150.028 158.353 169.356 1.00 38.39  ? 343  ARG B NH2 1 
ATOM   9461  N  N   . GLY B 1 344 ? 144.321 156.813 172.167 1.00 35.29  ? 344  GLY B N   1 
ATOM   9462  C  CA  . GLY B 1 344 ? 144.734 157.393 173.433 1.00 35.29  ? 344  GLY B CA  1 
ATOM   9463  C  C   . GLY B 1 344 ? 144.834 156.344 174.519 1.00 35.29  ? 344  GLY B C   1 
ATOM   9464  O  O   . GLY B 1 344 ? 145.805 156.309 175.281 1.00 35.29  ? 344  GLY B O   1 
ATOM   9465  N  N   . ALA B 1 345 ? 143.851 155.440 174.567 1.00 34.30  ? 345  ALA B N   1 
ATOM   9466  C  CA  . ALA B 1 345 ? 143.893 154.348 175.531 1.00 34.30  ? 345  ALA B CA  1 
ATOM   9467  C  C   . ALA B 1 345 ? 145.195 153.574 175.404 1.00 34.30  ? 345  ALA B C   1 
ATOM   9468  O  O   . ALA B 1 345 ? 145.878 153.317 176.403 1.00 34.30  ? 345  ALA B O   1 
ATOM   9469  C  CB  . ALA B 1 345 ? 142.689 153.427 175.334 1.00 34.30  ? 345  ALA B CB  1 
ATOM   9470  N  N   . VAL B 1 346 ? 145.583 153.241 174.170 1.00 34.81  ? 346  VAL B N   1 
ATOM   9471  C  CA  . VAL B 1 346 ? 146.842 152.534 173.972 1.00 34.81  ? 346  VAL B CA  1 
ATOM   9472  C  C   . VAL B 1 346 ? 147.998 153.368 174.500 1.00 34.81  ? 346  VAL B C   1 
ATOM   9473  O  O   . VAL B 1 346 ? 148.864 152.864 175.226 1.00 34.81  ? 346  VAL B O   1 
ATOM   9474  C  CB  . VAL B 1 346 ? 147.032 152.173 172.488 1.00 34.81  ? 346  VAL B CB  1 
ATOM   9475  C  CG1 . VAL B 1 346 ? 148.385 151.518 172.275 1.00 34.81  ? 346  VAL B CG1 1 
ATOM   9476  C  CG2 . VAL B 1 346 ? 145.917 151.254 172.024 1.00 34.81  ? 346  VAL B CG2 1 
ATOM   9477  N  N   . LYS B 1 347 ? 148.006 154.666 174.186 1.00 35.50  ? 347  LYS B N   1 
ATOM   9478  C  CA  . LYS B 1 347 ? 149.035 155.537 174.739 1.00 35.50  ? 347  LYS B CA  1 
ATOM   9479  C  C   . LYS B 1 347 ? 148.953 155.565 176.257 1.00 35.50  ? 347  LYS B C   1 
ATOM   9480  O  O   . LYS B 1 347 ? 149.981 155.551 176.943 1.00 35.50  ? 347  LYS B O   1 
ATOM   9481  C  CB  . LYS B 1 347 ? 148.905 156.946 174.163 1.00 35.50  ? 347  LYS B CB  1 
ATOM   9482  C  CG  . LYS B 1 347 ? 149.989 157.899 174.632 1.00 35.50  ? 347  LYS B CG  1 
ATOM   9483  C  CD  . LYS B 1 347 ? 150.527 158.732 173.483 1.00 35.50  ? 347  LYS B CD  1 
ATOM   9484  C  CE  . LYS B 1 347 ? 151.806 159.448 173.878 1.00 35.50  ? 347  LYS B CE  1 
ATOM   9485  N  NZ  . LYS B 1 347 ? 152.434 160.134 172.717 1.00 35.50  ? 347  LYS B NZ  1 
ATOM   9486  N  N   . LEU B 1 348 ? 147.733 155.574 176.800 1.00 31.67  ? 348  LEU B N   1 
ATOM   9487  C  CA  . LEU B 1 348 ? 147.584 155.539 178.248 1.00 31.67  ? 348  LEU B CA  1 
ATOM   9488  C  C   . LEU B 1 348 ? 148.123 154.234 178.817 1.00 31.67  ? 348  LEU B C   1 
ATOM   9489  O  O   . LEU B 1 348 ? 148.614 154.201 179.951 1.00 31.67  ? 348  LEU B O   1 
ATOM   9490  C  CB  . LEU B 1 348 ? 146.119 155.740 178.632 1.00 31.67  ? 348  LEU B CB  1 
ATOM   9491  C  CG  . LEU B 1 348 ? 145.741 157.205 178.852 1.00 31.67  ? 348  LEU B CG  1 
ATOM   9492  C  CD1 . LEU B 1 348 ? 144.384 157.362 179.509 1.00 31.67  ? 348  LEU B CD1 1 
ATOM   9493  C  CD2 . LEU B 1 348 ? 146.814 157.907 179.668 1.00 31.67  ? 348  LEU B CD2 1 
ATOM   9494  N  N   . SER B 1 349 ? 148.058 153.153 178.039 1.00 31.72  ? 349  SER B N   1 
ATOM   9495  C  CA  . SER B 1 349 ? 148.629 151.894 178.495 1.00 31.72  ? 349  SER B CA  1 
ATOM   9496  C  C   . SER B 1 349 ? 150.146 151.936 178.556 1.00 31.72  ? 349  SER B C   1 
ATOM   9497  O  O   . SER B 1 349 ? 150.746 151.087 179.222 1.00 31.72  ? 349  SER B O   1 
ATOM   9498  C  CB  . SER B 1 349 ? 148.173 150.756 177.589 1.00 31.72  ? 349  SER B CB  1 
ATOM   9499  O  OG  . SER B 1 349 ? 146.761 150.686 177.567 1.00 31.72  ? 349  SER B OG  1 
ATOM   9500  N  N   . LYS B 1 350 ? 150.777 152.894 177.879 1.00 32.88  ? 350  LYS B N   1 
ATOM   9501  C  CA  . LYS B 1 350 ? 152.213 153.094 177.992 1.00 32.88  ? 350  LYS B CA  1 
ATOM   9502  C  C   . LYS B 1 350 ? 152.580 154.085 179.086 1.00 32.88  ? 350  LYS B C   1 
ATOM   9503  O  O   . LYS B 1 350 ? 153.770 154.279 179.352 1.00 32.88  ? 350  LYS B O   1 
ATOM   9504  C  CB  . LYS B 1 350 ? 152.789 153.560 176.650 1.00 32.88  ? 350  LYS B CB  1 
ATOM   9505  C  CG  . LYS B 1 350 ? 152.494 152.606 175.503 1.00 32.88  ? 350  LYS B CG  1 
ATOM   9506  C  CD  . LYS B 1 350 ? 153.404 152.857 174.313 1.00 32.88  ? 350  LYS B CD  1 
ATOM   9507  C  CE  . LYS B 1 350 ? 152.813 152.275 173.038 1.00 32.88  ? 350  LYS B CE  1 
ATOM   9508  N  NZ  . LYS B 1 350 ? 151.702 153.108 172.505 1.00 32.88  ? 350  LYS B NZ  1 
ATOM   9509  N  N   . GLN B 1 351 ? 151.589 154.709 179.723 1.00 33.86  ? 351  GLN B N   1 
ATOM   9510  C  CA  . GLN B 1 351 ? 151.803 155.591 180.860 1.00 33.86  ? 351  GLN B CA  1 
ATOM   9511  C  C   . GLN B 1 351 ? 151.305 154.978 182.164 1.00 33.86  ? 351  GLN B C   1 
ATOM   9512  O  O   . GLN B 1 351 ? 150.995 155.713 183.108 1.00 33.86  ? 351  GLN B O   1 
ATOM   9513  C  CB  . GLN B 1 351 ? 151.128 156.941 180.617 1.00 33.86  ? 351  GLN B CB  1 
ATOM   9514  C  CG  . GLN B 1 351 ? 151.563 157.625 179.334 1.00 33.86  ? 351  GLN B CG  1 
ATOM   9515  C  CD  . GLN B 1 351 ? 151.146 159.080 179.279 1.00 33.86  ? 351  GLN B CD  1 
ATOM   9516  O  OE1 . GLN B 1 351 ? 150.489 159.584 180.190 1.00 33.86  ? 351  GLN B OE1 1 
ATOM   9517  N  NE2 . GLN B 1 351 ? 151.528 159.765 178.208 1.00 33.86  ? 351  GLN B NE2 1 
ATOM   9518  N  N   . LYS B 1 352 ? 151.213 153.647 182.224 1.00 31.67  ? 352  LYS B N   1 
ATOM   9519  C  CA  . LYS B 1 352 ? 150.767 152.921 183.416 1.00 31.67  ? 352  LYS B CA  1 
ATOM   9520  C  C   . LYS B 1 352 ? 149.342 153.320 183.811 1.00 31.67  ? 352  LYS B C   1 
ATOM   9521  O  O   . LYS B 1 352 ? 149.004 153.401 184.992 1.00 31.67  ? 352  LYS B O   1 
ATOM   9522  C  CB  . LYS B 1 352 ? 151.739 153.123 184.581 1.00 31.67  ? 352  LYS B CB  1 
ATOM   9523  C  CG  . LYS B 1 352 ? 152.922 152.171 184.570 1.00 31.67  ? 352  LYS B CG  1 
ATOM   9524  C  CD  . LYS B 1 352 ? 153.861 152.442 185.731 1.00 31.67  ? 352  LYS B CD  1 
ATOM   9525  C  CE  . LYS B 1 352 ? 154.775 153.616 185.435 1.00 31.67  ? 352  LYS B CE  1 
ATOM   9526  N  NZ  . LYS B 1 352 ? 155.878 153.724 186.429 1.00 31.67  ? 352  LYS B NZ  1 
ATOM   9527  N  N   . VAL B 1 353 ? 148.505 153.571 182.804 1.00 30.22  ? 353  VAL B N   1 
ATOM   9528  C  CA  . VAL B 1 353 ? 147.105 153.922 183.020 1.00 30.22  ? 353  VAL B CA  1 
ATOM   9529  C  C   . VAL B 1 353 ? 146.235 153.109 182.069 1.00 30.22  ? 353  VAL B C   1 
ATOM   9530  O  O   . VAL B 1 353 ? 146.083 153.464 180.895 1.00 30.22  ? 353  VAL B O   1 
ATOM   9531  C  CB  . VAL B 1 353 ? 146.867 155.432 182.825 1.00 30.22  ? 353  VAL B CB  1 
ATOM   9532  C  CG1 . VAL B 1 353 ? 145.389 155.757 182.928 1.00 30.22  ? 353  VAL B CG1 1 
ATOM   9533  C  CG2 . VAL B 1 353 ? 147.652 156.238 183.842 1.00 30.22  ? 353  VAL B CG2 1 
ATOM   9534  N  N   . ILE B 1 354 ? 145.660 152.015 182.558 1.00 32.25  ? 354  ILE B N   1 
ATOM   9535  C  CA  . ILE B 1 354 ? 144.802 151.153 181.756 1.00 32.25  ? 354  ILE B CA  1 
ATOM   9536  C  C   . ILE B 1 354 ? 143.378 151.681 181.836 1.00 32.25  ? 354  ILE B C   1 
ATOM   9537  O  O   . ILE B 1 354 ? 142.858 151.935 182.931 1.00 32.25  ? 354  ILE B O   1 
ATOM   9538  C  CB  . ILE B 1 354 ? 144.875 149.693 182.232 1.00 32.25  ? 354  ILE B CB  1 
ATOM   9539  C  CG1 . ILE B 1 354 ? 146.329 149.262 182.426 1.00 32.25  ? 354  ILE B CG1 1 
ATOM   9540  C  CG2 . ILE B 1 354 ? 144.193 148.784 181.230 1.00 32.25  ? 354  ILE B CG2 1 
ATOM   9541  C  CD1 . ILE B 1 354 ? 147.189 149.431 181.194 1.00 32.25  ? 354  ILE B CD1 1 
ATOM   9542  N  N   . VAL B 1 355 ? 142.748 151.848 180.677 1.00 31.17  ? 355  VAL B N   1 
ATOM   9543  C  CA  . VAL B 1 355 ? 141.382 152.346 180.578 1.00 31.17  ? 355  VAL B CA  1 
ATOM   9544  C  C   . VAL B 1 355 ? 140.481 151.169 180.236 1.00 31.17  ? 355  VAL B C   1 
ATOM   9545  O  O   . VAL B 1 355 ? 140.592 150.588 179.149 1.00 31.17  ? 355  VAL B O   1 
ATOM   9546  C  CB  . VAL B 1 355 ? 141.263 153.458 179.527 1.00 31.17  ? 355  VAL B CB  1 
ATOM   9547  C  CG1 . VAL B 1 355 ? 139.828 153.920 179.412 1.00 31.17  ? 355  VAL B CG1 1 
ATOM   9548  C  CG2 . VAL B 1 355 ? 142.171 154.613 179.887 1.00 31.17  ? 355  VAL B CG2 1 
ATOM   9549  N  N   . LYS B 1 356 ? 139.587 150.818 181.161 1.00 31.75  ? 356  LYS B N   1 
ATOM   9550  C  CA  . LYS B 1 356 ? 138.723 149.663 180.953 1.00 31.75  ? 356  LYS B CA  1 
ATOM   9551  C  C   . LYS B 1 356 ? 137.684 149.904 179.864 1.00 31.75  ? 356  LYS B C   1 
ATOM   9552  O  O   . LYS B 1 356 ? 137.422 149.004 179.059 1.00 31.75  ? 356  LYS B O   1 
ATOM   9553  C  CB  . LYS B 1 356 ? 138.041 149.279 182.266 1.00 31.75  ? 356  LYS B CB  1 
ATOM   9554  C  CG  . LYS B 1 356 ? 138.986 148.651 183.280 1.00 31.75  ? 356  LYS B CG  1 
ATOM   9555  C  CD  . LYS B 1 356 ? 138.300 148.392 184.612 1.00 31.75  ? 356  LYS B CD  1 
ATOM   9556  C  CE  . LYS B 1 356 ? 136.912 147.806 184.422 1.00 31.75  ? 356  LYS B CE  1 
ATOM   9557  N  NZ  . LYS B 1 356 ? 136.406 147.172 185.669 1.00 31.75  ? 356  LYS B NZ  1 
ATOM   9558  N  N   . HIS B 1 357 ? 137.091 151.094 179.815 1.00 36.65  ? 357  HIS B N   1 
ATOM   9559  C  CA  . HIS B 1 357 ? 136.103 151.436 178.797 1.00 36.65  ? 357  HIS B CA  1 
ATOM   9560  C  C   . HIS B 1 357 ? 136.402 152.831 178.272 1.00 36.65  ? 357  HIS B C   1 
ATOM   9561  O  O   . HIS B 1 357 ? 136.737 153.730 179.051 1.00 36.65  ? 357  HIS B O   1 
ATOM   9562  C  CB  . HIS B 1 357 ? 134.679 151.347 179.356 1.00 36.65  ? 357  HIS B CB  1 
ATOM   9563  C  CG  . HIS B 1 357 ? 134.344 152.422 180.341 1.00 36.65  ? 357  HIS B CG  1 
ATOM   9564  N  ND1 . HIS B 1 357 ? 133.258 153.257 180.191 1.00 36.65  ? 357  HIS B ND1 1 
ATOM   9565  C  CD2 . HIS B 1 357 ? 134.948 152.795 181.494 1.00 36.65  ? 357  HIS B CD2 1 
ATOM   9566  C  CE1 . HIS B 1 357 ? 133.208 154.100 181.206 1.00 36.65  ? 357  HIS B CE1 1 
ATOM   9567  N  NE2 . HIS B 1 357 ? 134.223 153.841 182.011 1.00 36.65  ? 357  HIS B NE2 1 
ATOM   9568  N  N   . LEU B 1 358 ? 136.268 153.011 176.955 1.00 37.24  ? 358  LEU B N   1 
ATOM   9569  C  CA  . LEU B 1 358 ? 136.716 154.241 176.305 1.00 37.24  ? 358  LEU B CA  1 
ATOM   9570  C  C   . LEU B 1 358 ? 135.985 155.474 176.820 1.00 37.24  ? 358  LEU B C   1 
ATOM   9571  O  O   . LEU B 1 358 ? 136.550 156.575 176.814 1.00 37.24  ? 358  LEU B O   1 
ATOM   9572  C  CB  . LEU B 1 358 ? 136.538 154.120 174.792 1.00 37.24  ? 358  LEU B CB  1 
ATOM   9573  C  CG  . LEU B 1 358 ? 137.390 153.054 174.101 1.00 37.24  ? 358  LEU B CG  1 
ATOM   9574  C  CD1 . LEU B 1 358 ? 137.227 153.129 172.594 1.00 37.24  ? 358  LEU B CD1 1 
ATOM   9575  C  CD2 . LEU B 1 358 ? 138.850 153.206 174.490 1.00 37.24  ? 358  LEU B CD2 1 
ATOM   9576  N  N   . ASP B 1 359 ? 134.737 155.313 177.267 1.00 42.56  ? 359  ASP B N   1 
ATOM   9577  C  CA  . ASP B 1 359 ? 133.960 156.442 177.772 1.00 42.56  ? 359  ASP B CA  1 
ATOM   9578  C  C   . ASP B 1 359 ? 134.729 157.203 178.845 1.00 42.56  ? 359  ASP B C   1 
ATOM   9579  O  O   . ASP B 1 359 ? 134.715 158.439 178.880 1.00 42.56  ? 359  ASP B O   1 
ATOM   9580  C  CB  . ASP B 1 359 ? 132.621 155.939 178.318 1.00 42.56  ? 359  ASP B CB  1 
ATOM   9581  C  CG  . ASP B 1 359 ? 131.726 157.058 178.829 1.00 42.56  ? 359  ASP B CG  1 
ATOM   9582  O  OD1 . ASP B 1 359 ? 132.063 158.245 178.654 1.00 42.56  ? 359  ASP B OD1 1 
ATOM   9583  O  OD2 . ASP B 1 359 ? 130.674 156.742 179.422 1.00 42.56  ? 359  ASP B OD2 1 
ATOM   9584  N  N   . ALA B 1 360 ? 135.431 156.475 179.714 1.00 36.35  ? 360  ALA B N   1 
ATOM   9585  C  CA  . ALA B 1 360 ? 136.177 157.080 180.809 1.00 36.35  ? 360  ALA B CA  1 
ATOM   9586  C  C   . ALA B 1 360 ? 137.122 158.158 180.300 1.00 36.35  ? 360  ALA B C   1 
ATOM   9587  O  O   . ALA B 1 360 ? 137.280 159.200 180.946 1.00 36.35  ? 360  ALA B O   1 
ATOM   9588  C  CB  . ALA B 1 360 ? 136.955 156.013 181.579 1.00 36.35  ? 360  ALA B CB  1 
ATOM   9589  N  N   . ILE B 1 361 ? 137.718 157.937 179.125 1.00 35.29  ? 361  ILE B N   1 
ATOM   9590  C  CA  . ILE B 1 361 ? 138.674 158.883 178.566 1.00 35.29  ? 361  ILE B CA  1 
ATOM   9591  C  C   . ILE B 1 361 ? 138.087 160.279 178.425 1.00 35.29  ? 361  ILE B C   1 
ATOM   9592  O  O   . ILE B 1 361 ? 138.817 161.268 178.550 1.00 35.29  ? 361  ILE B O   1 
ATOM   9593  C  CB  . ILE B 1 361 ? 139.198 158.362 177.209 1.00 35.29  ? 361  ILE B CB  1 
ATOM   9594  C  CG1 . ILE B 1 361 ? 139.946 157.043 177.403 1.00 35.29  ? 361  ILE B CG1 1 
ATOM   9595  C  CG2 . ILE B 1 361 ? 140.121 159.370 176.554 1.00 35.29  ? 361  ILE B CG2 1 
ATOM   9596  C  CD1 . ILE B 1 361 ? 140.323 156.360 176.110 1.00 35.29  ? 361  ILE B CD1 1 
ATOM   9597  N  N   . GLN B 1 362 ? 136.776 160.391 178.203 1.00 39.63  ? 362  GLN B N   1 
ATOM   9598  C  CA  . GLN B 1 362 ? 136.137 161.700 178.258 1.00 39.63  ? 362  GLN B CA  1 
ATOM   9599  C  C   . GLN B 1 362 ? 136.136 162.240 179.683 1.00 39.63  ? 362  GLN B C   1 
ATOM   9600  O  O   . GLN B 1 362 ? 136.710 163.299 179.960 1.00 39.63  ? 362  GLN B O   1 
ATOM   9601  C  CB  . GLN B 1 362 ? 134.705 161.620 177.724 1.00 39.63  ? 362  GLN B CB  1 
ATOM   9602  C  CG  . GLN B 1 362 ? 133.919 162.906 177.926 1.00 39.63  ? 362  GLN B CG  1 
ATOM   9603  C  CD  . GLN B 1 362 ? 132.420 162.693 177.893 1.00 39.63  ? 362  GLN B CD  1 
ATOM   9604  O  OE1 . GLN B 1 362 ? 131.945 161.570 177.742 1.00 39.63  ? 362  GLN B OE1 1 
ATOM   9605  N  NE2 . GLN B 1 362 ? 131.665 163.777 178.033 1.00 39.63  ? 362  GLN B NE2 1 
ATOM   9606  N  N   . ASN B 1 363 ? 135.505 161.506 180.604 1.00 39.11  ? 363  ASN B N   1 
ATOM   9607  C  CA  . ASN B 1 363 ? 135.383 161.983 181.978 1.00 39.11  ? 363  ASN B CA  1 
ATOM   9608  C  C   . ASN B 1 363 ? 136.750 162.143 182.628 1.00 39.11  ? 363  ASN B C   1 
ATOM   9609  O  O   . ASN B 1 363 ? 136.966 163.072 183.415 1.00 39.11  ? 363  ASN B O   1 
ATOM   9610  C  CB  . ASN B 1 363 ? 134.510 161.027 182.790 1.00 39.11  ? 363  ASN B CB  1 
ATOM   9611  C  CG  . ASN B 1 363 ? 133.044 161.119 182.420 1.00 39.11  ? 363  ASN B CG  1 
ATOM   9612  O  OD1 . ASN B 1 363 ? 132.465 160.174 181.887 1.00 39.11  ? 363  ASN B OD1 1 
ATOM   9613  N  ND2 . ASN B 1 363 ? 132.433 162.263 182.705 1.00 39.11  ? 363  ASN B ND2 1 
ATOM   9614  N  N   . PHE B 1 364 ? 137.690 161.255 182.298 1.00 36.87  ? 364  PHE B N   1 
ATOM   9615  C  CA  . PHE B 1 364 ? 139.023 161.338 182.881 1.00 36.87  ? 364  PHE B CA  1 
ATOM   9616  C  C   . PHE B 1 364 ? 139.731 162.616 182.454 1.00 36.87  ? 364  PHE B C   1 
ATOM   9617  O  O   . PHE B 1 364 ? 140.707 163.029 183.091 1.00 36.87  ? 364  PHE B O   1 
ATOM   9618  C  CB  . PHE B 1 364 ? 139.835 160.105 182.486 1.00 36.87  ? 364  PHE B CB  1 
ATOM   9619  C  CG  . PHE B 1 364 ? 141.128 159.964 183.226 1.00 36.87  ? 364  PHE B CG  1 
ATOM   9620  C  CD1 . PHE B 1 364 ? 141.133 159.561 184.550 1.00 36.87  ? 364  PHE B CD1 1 
ATOM   9621  C  CD2 . PHE B 1 364 ? 142.336 160.190 182.596 1.00 36.87  ? 364  PHE B CD2 1 
ATOM   9622  C  CE1 . PHE B 1 364 ? 142.317 159.415 185.240 1.00 36.87  ? 364  PHE B CE1 1 
ATOM   9623  C  CE2 . PHE B 1 364 ? 143.520 160.038 183.282 1.00 36.87  ? 364  PHE B CE2 1 
ATOM   9624  C  CZ  . PHE B 1 364 ? 143.513 159.653 184.605 1.00 36.87  ? 364  PHE B CZ  1 
ATOM   9625  N  N   . GLY B 1 365 ? 139.259 163.252 181.385 1.00 39.60  ? 365  GLY B N   1 
ATOM   9626  C  CA  . GLY B 1 365 ? 139.778 164.543 180.984 1.00 39.60  ? 365  GLY B CA  1 
ATOM   9627  C  C   . GLY B 1 365 ? 138.941 165.693 181.505 1.00 39.60  ? 365  GLY B C   1 
ATOM   9628  O  O   . GLY B 1 365 ? 139.423 166.825 181.604 1.00 39.60  ? 365  GLY B O   1 
ATOM   9629  N  N   . ALA B 1 366 ? 137.683 165.416 181.840 1.00 40.42  ? 366  ALA B N   1 
ATOM   9630  C  CA  . ALA B 1 366 ? 136.768 166.431 182.345 1.00 40.42  ? 366  ALA B CA  1 
ATOM   9631  C  C   . ALA B 1 366 ? 136.760 166.519 183.864 1.00 40.42  ? 366  ALA B C   1 
ATOM   9632  O  O   . ALA B 1 366 ? 136.011 167.329 184.420 1.00 40.42  ? 366  ALA B O   1 
ATOM   9633  C  CB  . ALA B 1 366 ? 135.347 166.160 181.839 1.00 40.42  ? 366  ALA B CB  1 
ATOM   9634  N  N   . MET B 1 367 ? 137.567 165.706 184.540 1.00 39.80  ? 367  MET B N   1 
ATOM   9635  C  CA  . MET B 1 367 ? 137.614 165.720 185.996 1.00 39.80  ? 367  MET B CA  1 
ATOM   9636  C  C   . MET B 1 367 ? 138.145 167.053 186.507 1.00 39.80  ? 367  MET B C   1 
ATOM   9637  O  O   . MET B 1 367 ? 139.131 167.584 185.989 1.00 39.80  ? 367  MET B O   1 
ATOM   9638  C  CB  . MET B 1 367 ? 138.495 164.574 186.492 1.00 39.80  ? 367  MET B CB  1 
ATOM   9639  C  CG  . MET B 1 367 ? 138.377 164.282 187.973 1.00 39.80  ? 367  MET B CG  1 
ATOM   9640  S  SD  . MET B 1 367 ? 139.384 162.867 188.450 1.00 39.80  ? 367  MET B SD  1 
ATOM   9641  C  CE  . MET B 1 367 ? 140.892 163.212 187.548 1.00 39.80  ? 367  MET B CE  1 
ATOM   9642  N  N   . ASP B 1 368 ? 137.484 167.595 187.532 1.00 43.31  ? 368  ASP B N   1 
ATOM   9643  C  CA  . ASP B 1 368 ? 137.950 168.806 188.190 1.00 43.31  ? 368  ASP B CA  1 
ATOM   9644  C  C   . ASP B 1 368 ? 137.966 168.693 189.708 1.00 43.31  ? 368  ASP B C   1 
ATOM   9645  O  O   . ASP B 1 368 ? 138.512 169.581 190.371 1.00 43.31  ? 368  ASP B O   1 
ATOM   9646  C  CB  . ASP B 1 368 ? 137.091 170.013 187.780 1.00 43.31  ? 368  ASP B CB  1 
ATOM   9647  C  CG  . ASP B 1 368 ? 135.637 169.856 188.170 1.00 43.31  ? 368  ASP B CG  1 
ATOM   9648  O  OD1 . ASP B 1 368 ? 135.206 168.711 188.416 1.00 43.31  ? 368  ASP B OD1 1 
ATOM   9649  O  OD2 . ASP B 1 368 ? 134.923 170.879 188.234 1.00 43.31  ? 368  ASP B OD2 1 
ATOM   9650  N  N   . ILE B 1 369 ? 137.384 167.639 190.274 1.00 41.24  ? 369  ILE B N   1 
ATOM   9651  C  CA  . ILE B 1 369 ? 137.447 167.369 191.707 1.00 41.24  ? 369  ILE B CA  1 
ATOM   9652  C  C   . ILE B 1 369 ? 137.839 165.907 191.863 1.00 41.24  ? 369  ILE B C   1 
ATOM   9653  O  O   . ILE B 1 369 ? 137.126 165.018 191.385 1.00 41.24  ? 369  ILE B O   1 
ATOM   9654  C  CB  . ILE B 1 369 ? 136.118 167.653 192.422 1.00 41.24  ? 369  ILE B CB  1 
ATOM   9655  C  CG1 . ILE B 1 369 ? 135.725 169.122 192.263 1.00 41.24  ? 369  ILE B CG1 1 
ATOM   9656  C  CG2 . ILE B 1 369 ? 136.218 167.285 193.890 1.00 41.24  ? 369  ILE B CG2 1 
ATOM   9657  C  CD1 . ILE B 1 369 ? 134.412 169.476 192.927 1.00 41.24  ? 369  ILE B CD1 1 
ATOM   9658  N  N   . LEU B 1 370 ? 138.964 165.653 192.524 1.00 36.08  ? 370  LEU B N   1 
ATOM   9659  C  CA  . LEU B 1 370 ? 139.490 164.302 192.696 1.00 36.08  ? 370  LEU B CA  1 
ATOM   9660  C  C   . LEU B 1 370 ? 139.518 163.977 194.186 1.00 36.08  ? 370  LEU B C   1 
ATOM   9661  O  O   . LEU B 1 370 ? 140.368 164.482 194.925 1.00 36.08  ? 370  LEU B O   1 
ATOM   9662  C  CB  . LEU B 1 370 ? 140.876 164.173 192.072 1.00 36.08  ? 370  LEU B CB  1 
ATOM   9663  C  CG  . LEU B 1 370 ? 141.628 162.873 192.361 1.00 36.08  ? 370  LEU B CG  1 
ATOM   9664  C  CD1 . LEU B 1 370 ? 140.995 161.714 191.614 1.00 36.08  ? 370  LEU B CD1 1 
ATOM   9665  C  CD2 . LEU B 1 370 ? 143.096 163.006 191.994 1.00 36.08  ? 370  LEU B CD2 1 
ATOM   9666  N  N   . CYS B 1 371 ? 138.584 163.138 194.623 1.00 36.22  ? 371  CYS B N   1 
ATOM   9667  C  CA  . CYS B 1 371 ? 138.569 162.673 196.001 1.00 36.22  ? 371  CYS B CA  1 
ATOM   9668  C  C   . CYS B 1 371 ? 139.491 161.471 196.157 1.00 36.22  ? 371  CYS B C   1 
ATOM   9669  O  O   . CYS B 1 371 ? 139.515 160.575 195.309 1.00 36.22  ? 371  CYS B O   1 
ATOM   9670  C  CB  . CYS B 1 371 ? 137.148 162.308 196.426 1.00 36.22  ? 371  CYS B CB  1 
ATOM   9671  S  SG  . CYS B 1 371 ? 135.886 163.476 195.878 1.00 36.22  ? 371  CYS B SG  1 
ATOM   9672  N  N   . THR B 1 372 ? 140.247 161.450 197.255 1.00 33.88  ? 372  THR B N   1 
ATOM   9673  C  CA  . THR B 1 372 ? 141.256 160.417 197.464 1.00 33.88  ? 372  THR B CA  1 
ATOM   9674  C  C   . THR B 1 372 ? 141.369 160.038 198.935 1.00 33.88  ? 372  THR B C   1 
ATOM   9675  O  O   . THR B 1 372 ? 140.493 160.366 199.741 1.00 33.88  ? 372  THR B O   1 
ATOM   9676  C  CB  . THR B 1 372 ? 142.625 160.881 196.956 1.00 33.88  ? 372  THR B CB  1 
ATOM   9677  O  OG1 . THR B 1 372 ? 142.852 162.238 197.356 1.00 33.88  ? 372  THR B OG1 1 
ATOM   9678  C  CG2 . THR B 1 372 ? 142.716 160.778 195.441 1.00 33.88  ? 372  THR B CG2 1 
ATOM   9679  N  N   . ASP B 1 373 ? 142.445 159.339 199.285 1.00 37.32  ? 373  ASP B N   1 
ATOM   9680  C  CA  . ASP B 1 373 ? 142.729 158.956 200.660 1.00 37.32  ? 373  ASP B CA  1 
ATOM   9681  C  C   . ASP B 1 373 ? 144.194 159.254 200.936 1.00 37.32  ? 373  ASP B C   1 
ATOM   9682  O  O   . ASP B 1 373 ? 145.020 159.251 200.018 1.00 37.32  ? 373  ASP B O   1 
ATOM   9683  C  CB  . ASP B 1 373 ? 142.418 157.471 200.903 1.00 37.32  ? 373  ASP B CB  1 
ATOM   9684  C  CG  . ASP B 1 373 ? 142.480 157.087 202.373 1.00 37.32  ? 373  ASP B CG  1 
ATOM   9685  O  OD1 . ASP B 1 373 ? 143.560 157.217 202.988 1.00 37.32  ? 373  ASP B OD1 1 
ATOM   9686  O  OD2 . ASP B 1 373 ? 141.443 156.649 202.915 1.00 37.32  ? 373  ASP B OD2 1 
ATOM   9687  N  N   . LYS B 1 374 ? 144.505 159.516 202.207 1.00 36.56  ? 374  LYS B N   1 
ATOM   9688  C  CA  . LYS B 1 374 ? 145.874 159.865 202.577 1.00 36.56  ? 374  LYS B CA  1 
ATOM   9689  C  C   . LYS B 1 374 ? 146.831 158.703 202.334 1.00 36.56  ? 374  LYS B C   1 
ATOM   9690  O  O   . LYS B 1 374 ? 147.955 158.901 201.858 1.00 36.56  ? 374  LYS B O   1 
ATOM   9691  C  CB  . LYS B 1 374 ? 145.922 160.319 204.038 1.00 36.56  ? 374  LYS B CB  1 
ATOM   9692  C  CG  . LYS B 1 374 ? 145.322 159.333 205.027 1.00 36.56  ? 374  LYS B CG  1 
ATOM   9693  C  CD  . LYS B 1 374 ? 145.396 159.860 206.448 1.00 36.56  ? 374  LYS B CD  1 
ATOM   9694  C  CE  . LYS B 1 374 ? 146.828 159.878 206.952 1.00 36.56  ? 374  LYS B CE  1 
ATOM   9695  N  NZ  . LYS B 1 374 ? 147.401 158.507 207.032 1.00 36.56  ? 374  LYS B NZ  1 
ATOM   9696  N  N   . THR B 1 375 ? 146.405 157.483 202.653 1.00 35.17  ? 375  THR B N   1 
ATOM   9697  C  CA  . THR B 1 375 ? 147.263 156.322 202.468 1.00 35.17  ? 375  THR B CA  1 
ATOM   9698  C  C   . THR B 1 375 ? 147.454 156.025 200.984 1.00 35.17  ? 375  THR B C   1 
ATOM   9699  O  O   . THR B 1 375 ? 146.525 156.134 200.180 1.00 35.17  ? 375  THR B O   1 
ATOM   9700  C  CB  . THR B 1 375 ? 146.669 155.101 203.172 1.00 35.17  ? 375  THR B CB  1 
ATOM   9701  O  OG1 . THR B 1 375 ? 146.166 155.487 204.456 1.00 35.17  ? 375  THR B OG1 1 
ATOM   9702  C  CG2 . THR B 1 375 ? 147.725 154.026 203.356 1.00 35.17  ? 375  THR B CG2 1 
ATOM   9703  N  N   . GLY B 1 376 ? 148.677 155.644 200.626 1.00 35.37  ? 376  GLY B N   1 
ATOM   9704  C  CA  . GLY B 1 376 ? 148.985 155.267 199.261 1.00 35.37  ? 376  GLY B CA  1 
ATOM   9705  C  C   . GLY B 1 376 ? 149.242 156.434 198.330 1.00 35.37  ? 376  GLY B C   1 
ATOM   9706  O  O   . GLY B 1 376 ? 150.303 156.510 197.704 1.00 35.37  ? 376  GLY B O   1 
ATOM   9707  N  N   . THR B 1 377 ? 148.279 157.351 198.226 1.00 36.11  ? 377  THR B N   1 
ATOM   9708  C  CA  . THR B 1 377 ? 148.423 158.480 197.312 1.00 36.11  ? 377  THR B CA  1 
ATOM   9709  C  C   . THR B 1 377 ? 149.327 159.558 197.900 1.00 36.11  ? 377  THR B C   1 
ATOM   9710  O  O   . THR B 1 377 ? 150.382 159.874 197.339 1.00 36.11  ? 377  THR B O   1 
ATOM   9711  C  CB  . THR B 1 377 ? 147.049 159.062 196.973 1.00 36.11  ? 377  THR B CB  1 
ATOM   9712  O  OG1 . THR B 1 377 ? 146.570 159.832 198.081 1.00 36.11  ? 377  THR B OG1 1 
ATOM   9713  C  CG2 . THR B 1 377 ? 146.060 157.950 196.674 1.00 36.11  ? 377  THR B CG2 1 
ATOM   9714  N  N   . LEU B 1 378 ? 148.929 160.132 199.033 1.00 35.50  ? 378  LEU B N   1 
ATOM   9715  C  CA  . LEU B 1 378 ? 149.718 161.180 199.667 1.00 35.50  ? 378  LEU B CA  1 
ATOM   9716  C  C   . LEU B 1 378 ? 150.941 160.587 200.355 1.00 35.50  ? 378  LEU B C   1 
ATOM   9717  O  O   . LEU B 1 378 ? 152.078 160.941 200.028 1.00 35.50  ? 378  LEU B O   1 
ATOM   9718  C  CB  . LEU B 1 378 ? 148.867 161.963 200.668 1.00 35.50  ? 378  LEU B CB  1 
ATOM   9719  C  CG  . LEU B 1 378 ? 148.238 163.258 200.150 1.00 35.50  ? 378  LEU B CG  1 
ATOM   9720  C  CD1 . LEU B 1 378 ? 147.225 162.969 199.054 1.00 35.50  ? 378  LEU B CD1 1 
ATOM   9721  C  CD2 . LEU B 1 378 ? 147.596 164.029 201.288 1.00 35.50  ? 378  LEU B CD2 1 
ATOM   9722  N  N   . THR B 1 379 ? 150.718 159.685 201.306 1.00 36.57  ? 379  THR B N   1 
ATOM   9723  C  CA  . THR B 1 379 ? 151.823 159.041 201.994 1.00 36.57  ? 379  THR B CA  1 
ATOM   9724  C  C   . THR B 1 379 ? 152.076 157.652 201.413 1.00 36.57  ? 379  THR B C   1 
ATOM   9725  O  O   . THR B 1 379 ? 151.274 157.107 200.650 1.00 36.57  ? 379  THR B O   1 
ATOM   9726  C  CB  . THR B 1 379 ? 151.538 158.943 203.491 1.00 36.57  ? 379  THR B CB  1 
ATOM   9727  O  OG1 . THR B 1 379 ? 150.377 158.132 203.703 1.00 36.57  ? 379  THR B OG1 1 
ATOM   9728  C  CG2 . THR B 1 379 ? 151.292 160.323 204.071 1.00 36.57  ? 379  THR B CG2 1 
ATOM   9729  N  N   . GLN B 1 380 ? 153.215 157.076 201.786 1.00 36.38  ? 380  GLN B N   1 
ATOM   9730  C  CA  . GLN B 1 380 ? 153.575 155.744 201.329 1.00 36.38  ? 380  GLN B CA  1 
ATOM   9731  C  C   . GLN B 1 380 ? 152.752 154.694 202.073 1.00 36.38  ? 380  GLN B C   1 
ATOM   9732  O  O   . GLN B 1 380 ? 152.018 154.992 203.017 1.00 36.38  ? 380  GLN B O   1 
ATOM   9733  C  CB  . GLN B 1 380 ? 155.070 155.502 201.522 1.00 36.38  ? 380  GLN B CB  1 
ATOM   9734  C  CG  . GLN B 1 380 ? 155.945 156.686 201.159 1.00 36.38  ? 380  GLN B CG  1 
ATOM   9735  C  CD  . GLN B 1 380 ? 157.397 156.473 201.537 1.00 36.38  ? 380  GLN B CD  1 
ATOM   9736  O  OE1 . GLN B 1 380 ? 157.769 155.417 202.047 1.00 36.38  ? 380  GLN B OE1 1 
ATOM   9737  N  NE2 . GLN B 1 380 ? 158.227 157.479 201.288 1.00 36.38  ? 380  GLN B NE2 1 
ATOM   9738  N  N   . ASP B 1 381 ? 152.866 153.443 201.633 1.00 41.58  ? 381  ASP B N   1 
ATOM   9739  C  CA  . ASP B 1 381 ? 152.233 152.323 202.314 1.00 41.58  ? 381  ASP B CA  1 
ATOM   9740  C  C   . ASP B 1 381 ? 153.164 151.655 203.315 1.00 41.58  ? 381  ASP B C   1 
ATOM   9741  O  O   . ASP B 1 381 ? 152.753 150.705 203.990 1.00 41.58  ? 381  ASP B O   1 
ATOM   9742  C  CB  . ASP B 1 381 ? 151.735 151.293 201.294 1.00 41.58  ? 381  ASP B CB  1 
ATOM   9743  C  CG  . ASP B 1 381 ? 150.684 150.360 201.869 1.00 41.58  ? 381  ASP B CG  1 
ATOM   9744  O  OD1 . ASP B 1 381 ? 149.524 150.794 202.029 1.00 41.58  ? 381  ASP B OD1 1 
ATOM   9745  O  OD2 . ASP B 1 381 ? 151.018 149.193 202.160 1.00 41.58  ? 381  ASP B OD2 1 
ATOM   9746  N  N   . LYS B 1 382 ? 154.400 152.128 203.431 1.00 42.95  ? 382  LYS B N   1 
ATOM   9747  C  CA  . LYS B 1 382 ? 155.378 151.588 204.362 1.00 42.95  ? 382  LYS B CA  1 
ATOM   9748  C  C   . LYS B 1 382 ? 155.706 152.637 205.414 1.00 42.95  ? 382  LYS B C   1 
ATOM   9749  O  O   . LYS B 1 382 ? 155.955 153.801 205.085 1.00 42.95  ? 382  LYS B O   1 
ATOM   9750  C  CB  . LYS B 1 382 ? 156.652 151.161 203.631 1.00 42.95  ? 382  LYS B CB  1 
ATOM   9751  C  CG  . LYS B 1 382 ? 157.720 150.574 204.533 1.00 42.95  ? 382  LYS B CG  1 
ATOM   9752  C  CD  . LYS B 1 382 ? 158.976 150.234 203.749 1.00 42.95  ? 382  LYS B CD  1 
ATOM   9753  C  CE  . LYS B 1 382 ? 160.004 149.556 204.636 1.00 42.95  ? 382  LYS B CE  1 
ATOM   9754  N  NZ  . LYS B 1 382 ? 160.457 150.454 205.732 1.00 42.95  ? 382  LYS B NZ  1 
ATOM   9755  N  N   . ILE B 1 383 ? 155.705 152.222 206.677 1.00 39.55  ? 383  ILE B N   1 
ATOM   9756  C  CA  . ILE B 1 383 ? 155.932 153.122 207.801 1.00 39.55  ? 383  ILE B CA  1 
ATOM   9757  C  C   . ILE B 1 383 ? 157.378 152.993 208.254 1.00 39.55  ? 383  ILE B C   1 
ATOM   9758  O  O   . ILE B 1 383 ? 157.914 151.882 208.351 1.00 39.55  ? 383  ILE B O   1 
ATOM   9759  C  CB  . ILE B 1 383 ? 154.954 152.835 208.953 1.00 39.55  ? 383  ILE B CB  1 
ATOM   9760  C  CG1 . ILE B 1 383 ? 154.934 151.347 209.300 1.00 39.55  ? 383  ILE B CG1 1 
ATOM   9761  C  CG2 . ILE B 1 383 ? 153.563 153.321 208.590 1.00 39.55  ? 383  ILE B CG2 1 
ATOM   9762  C  CD1 . ILE B 1 383 ? 153.926 151.006 210.371 1.00 39.55  ? 383  ILE B CD1 1 
ATOM   9763  N  N   . VAL B 1 384 ? 158.010 154.134 208.528 1.00 38.69  ? 384  VAL B N   1 
ATOM   9764  C  CA  . VAL B 1 384 ? 159.447 154.141 208.790 1.00 38.69  ? 384  VAL B CA  1 
ATOM   9765  C  C   . VAL B 1 384 ? 159.732 153.988 210.277 1.00 38.69  ? 384  VAL B C   1 
ATOM   9766  O  O   . VAL B 1 384 ? 160.441 153.067 210.697 1.00 38.69  ? 384  VAL B O   1 
ATOM   9767  C  CB  . VAL B 1 384 ? 160.089 155.419 208.223 1.00 38.69  ? 384  VAL B CB  1 
ATOM   9768  C  CG1 . VAL B 1 384 ? 161.511 155.566 208.740 1.00 38.69  ? 384  VAL B CG1 1 
ATOM   9769  C  CG2 . VAL B 1 384 ? 160.079 155.383 206.706 1.00 38.69  ? 384  VAL B CG2 1 
ATOM   9770  N  N   . LEU B 1 385 ? 159.191 154.883 211.094 1.00 34.22  ? 385  LEU B N   1 
ATOM   9771  C  CA  . LEU B 1 385 ? 159.442 154.889 212.526 1.00 34.22  ? 385  LEU B CA  1 
ATOM   9772  C  C   . LEU B 1 385 ? 158.236 154.329 213.261 1.00 34.22  ? 385  LEU B C   1 
ATOM   9773  O  O   . LEU B 1 385 ? 157.098 154.722 212.994 1.00 34.22  ? 385  LEU B O   1 
ATOM   9774  C  CB  . LEU B 1 385 ? 159.747 156.303 213.025 1.00 34.22  ? 385  LEU B CB  1 
ATOM   9775  C  CG  . LEU B 1 385 ? 160.066 156.481 214.510 1.00 34.22  ? 385  LEU B CG  1 
ATOM   9776  C  CD1 . LEU B 1 385 ? 161.186 157.484 214.674 1.00 34.22  ? 385  LEU B CD1 1 
ATOM   9777  C  CD2 . LEU B 1 385 ? 158.835 156.935 215.279 1.00 34.22  ? 385  LEU B CD2 1 
ATOM   9778  N  N   . GLU B 1 386 ? 158.494 153.409 214.185 1.00 36.04  ? 386  GLU B N   1 
ATOM   9779  C  CA  . GLU B 1 386 ? 157.438 152.858 215.017 1.00 36.04  ? 386  GLU B CA  1 
ATOM   9780  C  C   . GLU B 1 386 ? 158.031 152.489 216.368 1.00 36.04  ? 386  GLU B C   1 
ATOM   9781  O  O   . GLU B 1 386 ? 159.112 151.900 216.439 1.00 36.04  ? 386  GLU B O   1 
ATOM   9782  C  CB  . GLU B 1 386 ? 156.778 151.640 214.357 1.00 36.04  ? 386  GLU B CB  1 
ATOM   9783  C  CG  . GLU B 1 386 ? 157.706 150.461 214.119 1.00 36.04  ? 386  GLU B CG  1 
ATOM   9784  C  CD  . GLU B 1 386 ? 157.649 149.445 215.241 1.00 36.04  ? 386  GLU B CD  1 
ATOM   9785  O  OE1 . GLU B 1 386 ? 156.636 149.422 215.971 1.00 36.04  ? 386  GLU B OE1 1 
ATOM   9786  O  OE2 . GLU B 1 386 ? 158.618 148.673 215.395 1.00 36.04  ? 386  GLU B OE2 1 
ATOM   9787  N  N   . ASN B 1 387 ? 157.328 152.861 217.433 1.00 39.89  ? 387  ASN B N   1 
ATOM   9788  C  CA  . ASN B 1 387 ? 157.743 152.539 218.789 1.00 39.89  ? 387  ASN B CA  1 
ATOM   9789  C  C   . ASN B 1 387 ? 156.560 151.958 219.548 1.00 39.89  ? 387  ASN B C   1 
ATOM   9790  O  O   . ASN B 1 387 ? 155.461 152.521 219.523 1.00 39.89  ? 387  ASN B O   1 
ATOM   9791  C  CB  . ASN B 1 387 ? 158.311 153.770 219.510 1.00 39.89  ? 387  ASN B CB  1 
ATOM   9792  C  CG  . ASN B 1 387 ? 157.417 154.990 219.393 1.00 39.89  ? 387  ASN B CG  1 
ATOM   9793  O  OD1 . ASN B 1 387 ? 156.339 154.938 218.806 1.00 39.89  ? 387  ASN B OD1 1 
ATOM   9794  N  ND2 . ASN B 1 387 ? 157.869 156.104 219.956 1.00 39.89  ? 387  ASN B ND2 1 
ATOM   9795  N  N   . HIS B 1 388 ? 156.787 150.828 220.208 1.00 47.87  ? 388  HIS B N   1 
ATOM   9796  C  CA  . HIS B 1 388 ? 155.758 150.123 220.962 1.00 47.87  ? 388  HIS B CA  1 
ATOM   9797  C  C   . HIS B 1 388 ? 155.961 150.416 222.443 1.00 47.87  ? 388  HIS B C   1 
ATOM   9798  O  O   . HIS B 1 388 ? 156.925 149.942 223.054 1.00 47.87  ? 388  HIS B O   1 
ATOM   9799  C  CB  . HIS B 1 388 ? 155.800 148.624 220.662 1.00 47.87  ? 388  HIS B CB  1 
ATOM   9800  C  CG  . HIS B 1 388 ? 157.107 147.974 220.994 1.00 47.87  ? 388  HIS B CG  1 
ATOM   9801  N  ND1 . HIS B 1 388 ? 157.400 147.488 222.250 1.00 47.87  ? 388  HIS B ND1 1 
ATOM   9802  C  CD2 . HIS B 1 388 ? 158.199 147.728 220.232 1.00 47.87  ? 388  HIS B CD2 1 
ATOM   9803  C  CE1 . HIS B 1 388 ? 158.616 146.971 222.248 1.00 47.87  ? 388  HIS B CE1 1 
ATOM   9804  N  NE2 . HIS B 1 388 ? 159.122 147.104 221.036 1.00 47.87  ? 388  HIS B NE2 1 
ATOM   9805  N  N   . THR B 1 389 ? 155.060 151.209 223.013 1.00 48.31  ? 389  THR B N   1 
ATOM   9806  C  CA  . THR B 1 389 ? 155.151 151.659 224.393 1.00 48.31  ? 389  THR B CA  1 
ATOM   9807  C  C   . THR B 1 389 ? 153.838 151.392 225.117 1.00 48.31  ? 389  THR B C   1 
ATOM   9808  O  O   . THR B 1 389 ? 152.779 151.240 224.505 1.00 48.31  ? 389  THR B O   1 
ATOM   9809  C  CB  . THR B 1 389 ? 155.492 153.153 224.471 1.00 48.31  ? 389  THR B CB  1 
ATOM   9810  O  OG1 . THR B 1 389 ? 154.348 153.926 224.085 1.00 48.31  ? 389  THR B OG1 1 
ATOM   9811  C  CG2 . THR B 1 389 ? 156.660 153.493 223.558 1.00 48.31  ? 389  THR B CG2 1 
ATOM   9812  N  N   . ASP B 1 390 ? 153.921 151.334 226.442 1.00 51.65  ? 390  ASP B N   1 
ATOM   9813  C  CA  . ASP B 1 390 ? 152.741 151.196 227.279 1.00 51.65  ? 390  ASP B CA  1 
ATOM   9814  C  C   . ASP B 1 390 ? 152.150 152.581 227.543 1.00 51.65  ? 390  ASP B C   1 
ATOM   9815  O  O   . ASP B 1 390 ? 152.526 153.571 226.911 1.00 51.65  ? 390  ASP B O   1 
ATOM   9816  C  CB  . ASP B 1 390 ? 153.086 150.458 228.572 1.00 51.65  ? 390  ASP B CB  1 
ATOM   9817  C  CG  . ASP B 1 390 ? 154.186 151.141 229.363 1.00 51.65  ? 390  ASP B CG  1 
ATOM   9818  O  OD1 . ASP B 1 390 ? 154.721 152.166 228.891 1.00 51.65  ? 390  ASP B OD1 1 
ATOM   9819  O  OD2 . ASP B 1 390 ? 154.518 150.651 230.463 1.00 51.65  ? 390  ASP B OD2 1 
ATOM   9820  N  N   . ILE B 1 391 ? 151.208 152.662 228.485 1.00 51.53  ? 391  ILE B N   1 
ATOM   9821  C  CA  . ILE B 1 391 ? 150.565 153.936 228.781 1.00 51.53  ? 391  ILE B CA  1 
ATOM   9822  C  C   . ILE B 1 391 ? 151.533 154.935 229.400 1.00 51.53  ? 391  ILE B C   1 
ATOM   9823  O  O   . ILE B 1 391 ? 151.344 156.148 229.249 1.00 51.53  ? 391  ILE B O   1 
ATOM   9824  C  CB  . ILE B 1 391 ? 149.344 153.722 229.694 1.00 51.53  ? 391  ILE B CB  1 
ATOM   9825  C  CG1 . ILE B 1 391 ? 149.776 153.192 231.061 1.00 51.53  ? 391  ILE B CG1 1 
ATOM   9826  C  CG2 . ILE B 1 391 ? 148.363 152.766 229.042 1.00 51.53  ? 391  ILE B CG2 1 
ATOM   9827  C  CD1 . ILE B 1 391 ? 148.741 153.389 232.144 1.00 51.53  ? 391  ILE B CD1 1 
ATOM   9828  N  N   . SER B 1 392 ? 152.568 154.464 230.094 1.00 54.00  ? 392  SER B N   1 
ATOM   9829  C  CA  . SER B 1 392 ? 153.524 155.349 230.746 1.00 54.00  ? 392  SER B CA  1 
ATOM   9830  C  C   . SER B 1 392 ? 154.561 155.917 229.788 1.00 54.00  ? 392  SER B C   1 
ATOM   9831  O  O   . SER B 1 392 ? 155.297 156.833 230.171 1.00 54.00  ? 392  SER B O   1 
ATOM   9832  C  CB  . SER B 1 392 ? 154.233 154.612 231.887 1.00 54.00  ? 392  SER B CB  1 
ATOM   9833  O  OG  . SER B 1 392 ? 154.872 153.437 231.418 1.00 54.00  ? 392  SER B OG  1 
ATOM   9834  N  N   . GLY B 1 393 ? 154.638 155.404 228.563 1.00 52.00  ? 393  GLY B N   1 
ATOM   9835  C  CA  . GLY B 1 393 ? 155.568 155.893 227.565 1.00 52.00  ? 393  GLY B CA  1 
ATOM   9836  C  C   . GLY B 1 393 ? 156.815 155.055 227.395 1.00 52.00  ? 393  GLY B C   1 
ATOM   9837  O  O   . GLY B 1 393 ? 157.483 155.176 226.360 1.00 52.00  ? 393  GLY B O   1 
ATOM   9838  N  N   . LYS B 1 394 ? 157.157 154.215 228.369 1.00 51.77  ? 394  LYS B N   1 
ATOM   9839  C  CA  . LYS B 1 394 ? 158.324 153.351 228.246 1.00 51.77  ? 394  LYS B CA  1 
ATOM   9840  C  C   . LYS B 1 394 ? 158.035 152.228 227.256 1.00 51.77  ? 394  LYS B C   1 
ATOM   9841  O  O   . LYS B 1 394 ? 156.892 151.774 227.138 1.00 51.77  ? 394  LYS B O   1 
ATOM   9842  C  CB  . LYS B 1 394 ? 158.710 152.785 229.611 1.00 51.77  ? 394  LYS B CB  1 
ATOM   9843  C  CG  . LYS B 1 394 ? 157.748 151.742 230.160 1.00 51.77  ? 394  LYS B CG  1 
ATOM   9844  C  CD  . LYS B 1 394 ? 158.222 151.205 231.499 1.00 51.77  ? 394  LYS B CD  1 
ATOM   9845  C  CE  . LYS B 1 394 ? 157.903 152.175 232.623 1.00 51.77  ? 394  LYS B CE  1 
ATOM   9846  N  NZ  . LYS B 1 394 ? 156.438 152.274 232.868 1.00 51.77  ? 394  LYS B NZ  1 
ATOM   9847  N  N   . THR B 1 395 ? 159.066 151.789 226.535 1.00 49.75  ? 395  THR B N   1 
ATOM   9848  C  CA  . THR B 1 395 ? 158.914 150.680 225.602 1.00 49.75  ? 395  THR B CA  1 
ATOM   9849  C  C   . THR B 1 395 ? 158.505 149.414 226.346 1.00 49.75  ? 395  THR B C   1 
ATOM   9850  O  O   . THR B 1 395 ? 159.060 149.094 227.402 1.00 49.75  ? 395  THR B O   1 
ATOM   9851  C  CB  . THR B 1 395 ? 160.203 150.465 224.798 1.00 49.75  ? 395  THR B CB  1 
ATOM   9852  O  OG1 . THR B 1 395 ? 159.983 149.473 223.786 1.00 49.75  ? 395  THR B OG1 1 
ATOM   9853  C  CG2 . THR B 1 395 ? 161.365 150.042 225.694 1.00 49.75  ? 395  THR B CG2 1 
ATOM   9854  N  N   . SER B 1 396 ? 157.508 148.706 225.825 1.00 52.87  ? 396  SER B N   1 
ATOM   9855  C  CA  . SER B 1 396 ? 156.989 147.497 226.452 1.00 52.87  ? 396  SER B CA  1 
ATOM   9856  C  C   . SER B 1 396 ? 157.045 146.355 225.449 1.00 52.87  ? 396  SER B C   1 
ATOM   9857  O  O   . SER B 1 396 ? 156.539 146.482 224.329 1.00 52.87  ? 396  SER B O   1 
ATOM   9858  C  CB  . SER B 1 396 ? 155.559 147.708 226.948 1.00 52.87  ? 396  SER B CB  1 
ATOM   9859  O  OG  . SER B 1 396 ? 154.996 146.491 227.405 1.00 52.87  ? 396  SER B OG  1 
ATOM   9860  N  N   . GLU B 1 397 ? 157.657 145.241 225.853 1.00 58.90  ? 397  GLU B N   1 
ATOM   9861  C  CA  . GLU B 1 397 ? 157.711 144.074 224.980 1.00 58.90  ? 397  GLU B CA  1 
ATOM   9862  C  C   . GLU B 1 397 ? 156.369 143.355 224.931 1.00 58.90  ? 397  GLU B C   1 
ATOM   9863  O  O   . GLU B 1 397 ? 156.063 142.676 223.944 1.00 58.90  ? 397  GLU B O   1 
ATOM   9864  C  CB  . GLU B 1 397 ? 158.816 143.125 225.446 1.00 58.90  ? 397  GLU B CB  1 
ATOM   9865  C  CG  . GLU B 1 397 ? 159.065 141.943 224.525 1.00 58.90  ? 397  GLU B CG  1 
ATOM   9866  C  CD  . GLU B 1 397 ? 160.243 141.099 224.967 1.00 58.90  ? 397  GLU B CD  1 
ATOM   9867  O  OE1 . GLU B 1 397 ? 160.237 140.630 226.125 1.00 58.90  ? 397  GLU B OE1 1 
ATOM   9868  O  OE2 . GLU B 1 397 ? 161.176 140.903 224.160 1.00 58.90  ? 397  GLU B OE2 1 
ATOM   9869  N  N   . ARG B 1 398 ? 155.558 143.495 225.983 1.00 57.08  ? 398  ARG B N   1 
ATOM   9870  C  CA  . ARG B 1 398 ? 154.249 142.850 226.010 1.00 57.08  ? 398  ARG B CA  1 
ATOM   9871  C  C   . ARG B 1 398 ? 153.354 143.375 224.894 1.00 57.08  ? 398  ARG B C   1 
ATOM   9872  O  O   . ARG B 1 398 ? 152.651 142.604 224.230 1.00 57.08  ? 398  ARG B O   1 
ATOM   9873  C  CB  . ARG B 1 398 ? 153.590 143.064 227.372 1.00 57.08  ? 398  ARG B CB  1 
ATOM   9874  C  CG  . ARG B 1 398 ? 152.227 142.407 227.510 1.00 57.08  ? 398  ARG B CG  1 
ATOM   9875  C  CD  . ARG B 1 398 ? 152.334 140.892 227.487 1.00 57.08  ? 398  ARG B CD  1 
ATOM   9876  N  NE  . ARG B 1 398 ? 153.168 140.390 228.572 1.00 57.08  ? 398  ARG B NE  1 
ATOM   9877  C  CZ  . ARG B 1 398 ? 152.736 140.166 229.805 1.00 57.08  ? 398  ARG B CZ  1 
ATOM   9878  N  NH1 . ARG B 1 398 ? 151.478 140.390 230.148 1.00 57.08  ? 398  ARG B NH1 1 
ATOM   9879  N  NH2 . ARG B 1 398 ? 153.587 139.706 230.718 1.00 57.08  ? 398  ARG B NH2 1 
ATOM   9880  N  N   . VAL B 1 399 ? 153.365 144.692 224.677 1.00 50.65  ? 399  VAL B N   1 
ATOM   9881  C  CA  . VAL B 1 399 ? 152.542 145.286 223.627 1.00 50.65  ? 399  VAL B CA  1 
ATOM   9882  C  C   . VAL B 1 399 ? 152.968 144.768 222.262 1.00 50.65  ? 399  VAL B C   1 
ATOM   9883  O  O   . VAL B 1 399 ? 152.131 144.405 221.425 1.00 50.65  ? 399  VAL B O   1 
ATOM   9884  C  CB  . VAL B 1 399 ? 152.622 146.822 223.694 1.00 50.65  ? 399  VAL B CB  1 
ATOM   9885  C  CG1 . VAL B 1 399 ? 151.764 147.447 222.608 1.00 50.65  ? 399  VAL B CG1 1 
ATOM   9886  C  CG2 . VAL B 1 399 ? 152.204 147.311 225.068 1.00 50.65  ? 399  VAL B CG2 1 
ATOM   9887  N  N   . LEU B 1 400 ? 154.278 144.726 222.017 1.00 52.30  ? 400  LEU B N   1 
ATOM   9888  C  CA  . LEU B 1 400 ? 154.787 144.246 220.740 1.00 52.30  ? 400  LEU B CA  1 
ATOM   9889  C  C   . LEU B 1 400 ? 154.438 142.779 220.523 1.00 52.30  ? 400  LEU B C   1 
ATOM   9890  O  O   . LEU B 1 400 ? 154.073 142.381 219.414 1.00 52.30  ? 400  LEU B O   1 
ATOM   9891  C  CB  . LEU B 1 400 ? 156.299 144.457 220.662 1.00 52.30  ? 400  LEU B CB  1 
ATOM   9892  C  CG  . LEU B 1 400 ? 156.966 144.021 219.357 1.00 52.30  ? 400  LEU B CG  1 
ATOM   9893  C  CD1 . LEU B 1 400 ? 156.555 144.942 218.221 1.00 52.30  ? 400  LEU B CD1 1 
ATOM   9894  C  CD2 . LEU B 1 400 ? 158.477 143.996 219.509 1.00 52.30  ? 400  LEU B CD2 1 
ATOM   9895  N  N   . HIS B 1 401 ? 154.538 141.961 221.573 1.00 54.76  ? 401  HIS B N   1 
ATOM   9896  C  CA  . HIS B 1 401 ? 154.211 140.545 221.429 1.00 54.76  ? 401  HIS B CA  1 
ATOM   9897  C  C   . HIS B 1 401 ? 152.721 140.336 221.182 1.00 54.76  ? 401  HIS B C   1 
ATOM   9898  O  O   . HIS B 1 401 ? 152.335 139.481 220.377 1.00 54.76  ? 401  HIS B O   1 
ATOM   9899  C  CB  . HIS B 1 401 ? 154.672 139.771 222.663 1.00 54.76  ? 401  HIS B CB  1 
ATOM   9900  C  CG  . HIS B 1 401 ? 156.148 139.528 222.701 1.00 54.76  ? 401  HIS B CG  1 
ATOM   9901  N  ND1 . HIS B 1 401 ? 156.954 139.674 221.593 1.00 54.76  ? 401  HIS B ND1 1 
ATOM   9902  C  CD2 . HIS B 1 401 ? 156.964 139.144 223.711 1.00 54.76  ? 401  HIS B CD2 1 
ATOM   9903  C  CE1 . HIS B 1 401 ? 158.203 139.394 221.919 1.00 54.76  ? 401  HIS B CE1 1 
ATOM   9904  N  NE2 . HIS B 1 401 ? 158.236 139.068 223.198 1.00 54.76  ? 401  HIS B NE2 1 
ATOM   9905  N  N   . SER B 1 402 ? 151.866 141.101 221.866 1.00 53.15  ? 402  SER B N   1 
ATOM   9906  C  CA  . SER B 1 402 ? 150.431 140.992 221.619 1.00 53.15  ? 402  SER B CA  1 
ATOM   9907  C  C   . SER B 1 402 ? 150.085 141.415 220.196 1.00 53.15  ? 402  SER B C   1 
ATOM   9908  O  O   . SER B 1 402 ? 149.281 140.758 219.519 1.00 53.15  ? 402  SER B O   1 
ATOM   9909  C  CB  . SER B 1 402 ? 149.655 141.831 222.633 1.00 53.15  ? 402  SER B CB  1 
ATOM   9910  O  OG  . SER B 1 402 ? 149.805 141.312 223.942 1.00 53.15  ? 402  SER B OG  1 
ATOM   9911  N  N   . ALA B 1 403 ? 150.685 142.510 219.724 1.00 52.34  ? 403  ALA B N   1 
ATOM   9912  C  CA  . ALA B 1 403 ? 150.463 142.929 218.346 1.00 52.34  ? 403  ALA B CA  1 
ATOM   9913  C  C   . ALA B 1 403 ? 150.975 141.890 217.360 1.00 52.34  ? 403  ALA B C   1 
ATOM   9914  O  O   . ALA B 1 403 ? 150.342 141.657 216.326 1.00 52.34  ? 403  ALA B O   1 
ATOM   9915  C  CB  . ALA B 1 403 ? 151.127 144.279 218.090 1.00 52.34  ? 403  ALA B CB  1 
ATOM   9916  N  N   . TRP B 1 404 ? 152.113 141.259 217.659 1.00 55.97  ? 404  TRP B N   1 
ATOM   9917  C  CA  . TRP B 1 404 ? 152.623 140.207 216.790 1.00 55.97  ? 404  TRP B CA  1 
ATOM   9918  C  C   . TRP B 1 404 ? 151.667 139.027 216.735 1.00 55.97  ? 404  TRP B C   1 
ATOM   9919  O  O   . TRP B 1 404 ? 151.433 138.465 215.662 1.00 55.97  ? 404  TRP B O   1 
ATOM   9920  C  CB  . TRP B 1 404 ? 154.002 139.750 217.260 1.00 55.97  ? 404  TRP B CB  1 
ATOM   9921  C  CG  . TRP B 1 404 ? 154.624 138.740 216.350 1.00 55.97  ? 404  TRP B CG  1 
ATOM   9922  C  CD1 . TRP B 1 404 ? 155.498 138.984 215.334 1.00 55.97  ? 404  TRP B CD1 1 
ATOM   9923  C  CD2 . TRP B 1 404 ? 154.414 137.323 216.367 1.00 55.97  ? 404  TRP B CD2 1 
ATOM   9924  N  NE1 . TRP B 1 404 ? 155.849 137.808 214.718 1.00 55.97  ? 404  TRP B NE1 1 
ATOM   9925  C  CE2 . TRP B 1 404 ? 155.196 136.773 215.334 1.00 55.97  ? 404  TRP B CE2 1 
ATOM   9926  C  CE3 . TRP B 1 404 ? 153.642 136.466 217.157 1.00 55.97  ? 404  TRP B CE3 1 
ATOM   9927  C  CZ2 . TRP B 1 404 ? 155.228 135.407 215.069 1.00 55.97  ? 404  TRP B CZ2 1 
ATOM   9928  C  CZ3 . TRP B 1 404 ? 153.674 135.111 216.892 1.00 55.97  ? 404  TRP B CZ3 1 
ATOM   9929  C  CH2 . TRP B 1 404 ? 154.462 134.594 215.858 1.00 55.97  ? 404  TRP B CH2 1 
ATOM   9930  N  N   . LEU B 1 405 ? 151.118 138.628 217.883 1.00 55.22  ? 405  LEU B N   1 
ATOM   9931  C  CA  . LEU B 1 405 ? 150.146 137.540 217.896 1.00 55.22  ? 405  LEU B CA  1 
ATOM   9932  C  C   . LEU B 1 405 ? 148.931 137.890 217.046 1.00 55.22  ? 405  LEU B C   1 
ATOM   9933  O  O   . LEU B 1 405 ? 148.496 137.096 216.200 1.00 55.22  ? 405  LEU B O   1 
ATOM   9934  C  CB  . LEU B 1 405 ? 149.728 137.230 219.332 1.00 55.22  ? 405  LEU B CB  1 
ATOM   9935  C  CG  . LEU B 1 405 ? 150.660 136.321 220.132 1.00 55.22  ? 405  LEU B CG  1 
ATOM   9936  C  CD1 . LEU B 1 405 ? 150.266 136.313 221.600 1.00 55.22  ? 405  LEU B CD1 1 
ATOM   9937  C  CD2 . LEU B 1 405 ? 150.639 134.917 219.560 1.00 55.22  ? 405  LEU B CD2 1 
ATOM   9938  N  N   . ASN B 1 406 ? 148.388 139.095 217.242 1.00 52.43  ? 406  ASN B N   1 
ATOM   9939  C  CA  . ASN B 1 406 ? 147.200 139.502 216.498 1.00 52.43  ? 406  ASN B CA  1 
ATOM   9940  C  C   . ASN B 1 406 ? 147.477 139.567 215.000 1.00 52.43  ? 406  ASN B C   1 
ATOM   9941  O  O   . ASN B 1 406 ? 146.628 139.179 214.189 1.00 52.43  ? 406  ASN B O   1 
ATOM   9942  C  CB  . ASN B 1 406 ? 146.697 140.850 217.014 1.00 52.43  ? 406  ASN B CB  1 
ATOM   9943  C  CG  . ASN B 1 406 ? 145.364 141.252 216.410 1.00 52.43  ? 406  ASN B CG  1 
ATOM   9944  O  OD1 . ASN B 1 406 ? 145.259 141.496 215.209 1.00 52.43  ? 406  ASN B OD1 1 
ATOM   9945  N  ND2 . ASN B 1 406 ? 144.337 141.326 217.246 1.00 52.43  ? 406  ASN B ND2 1 
ATOM   9946  N  N   . SER B 1 407 ? 148.657 140.057 214.612 1.00 53.61  ? 407  SER B N   1 
ATOM   9947  C  CA  . SER B 1 407 ? 148.970 140.200 213.194 1.00 53.61  ? 407  SER B CA  1 
ATOM   9948  C  C   . SER B 1 407 ? 149.284 138.857 212.547 1.00 53.61  ? 407  SER B C   1 
ATOM   9949  O  O   . SER B 1 407 ? 148.944 138.631 211.380 1.00 53.61  ? 407  SER B O   1 
ATOM   9950  C  CB  . SER B 1 407 ? 150.142 141.162 213.014 1.00 53.61  ? 407  SER B CB  1 
ATOM   9951  O  OG  . SER B 1 407 ? 149.779 142.478 213.388 1.00 53.61  ? 407  SER B OG  1 
ATOM   9952  N  N   . HIS B 1 408 ? 149.945 137.960 213.278 1.00 57.14  ? 408  HIS B N   1 
ATOM   9953  C  CA  . HIS B 1 408 ? 150.348 136.687 212.696 1.00 57.14  ? 408  HIS B CA  1 
ATOM   9954  C  C   . HIS B 1 408 ? 149.171 135.728 212.596 1.00 57.14  ? 408  HIS B C   1 
ATOM   9955  O  O   . HIS B 1 408 ? 149.069 134.963 211.630 1.00 57.14  ? 408  HIS B O   1 
ATOM   9956  C  CB  . HIS B 1 408 ? 151.478 136.075 213.523 1.00 57.14  ? 408  HIS B CB  1 
ATOM   9957  C  CG  . HIS B 1 408 ? 152.003 134.786 212.974 1.00 57.14  ? 408  HIS B CG  1 
ATOM   9958  N  ND1 . HIS B 1 408 ? 152.870 134.732 211.903 1.00 57.14  ? 408  HIS B ND1 1 
ATOM   9959  C  CD2 . HIS B 1 408 ? 151.790 133.503 213.350 1.00 57.14  ? 408  HIS B CD2 1 
ATOM   9960  C  CE1 . HIS B 1 408 ? 153.165 133.471 211.642 1.00 57.14  ? 408  HIS B CE1 1 
ATOM   9961  N  NE2 . HIS B 1 408 ? 152.523 132.705 212.505 1.00 57.14  ? 408  HIS B NE2 1 
ATOM   9962  N  N   . TYR B 1 409 ? 148.269 135.754 213.574 1.00 61.91  ? 409  TYR B N   1 
ATOM   9963  C  CA  . TYR B 1 409 ? 147.148 134.826 213.582 1.00 61.91  ? 409  TYR B CA  1 
ATOM   9964  C  C   . TYR B 1 409 ? 145.894 135.391 212.927 1.00 61.91  ? 409  TYR B C   1 
ATOM   9965  O  O   . TYR B 1 409 ? 144.846 134.737 212.967 1.00 61.91  ? 409  TYR B O   1 
ATOM   9966  C  CB  . TYR B 1 409 ? 146.844 134.386 215.015 1.00 61.91  ? 409  TYR B CB  1 
ATOM   9967  C  CG  . TYR B 1 409 ? 147.793 133.322 215.512 1.00 61.91  ? 409  TYR B CG  1 
ATOM   9968  C  CD1 . TYR B 1 409 ? 148.020 132.171 214.770 1.00 61.91  ? 409  TYR B CD1 1 
ATOM   9969  C  CD2 . TYR B 1 409 ? 148.473 133.472 216.712 1.00 61.91  ? 409  TYR B CD2 1 
ATOM   9970  C  CE1 . TYR B 1 409 ? 148.887 131.195 215.213 1.00 61.91  ? 409  TYR B CE1 1 
ATOM   9971  C  CE2 . TYR B 1 409 ? 149.344 132.500 217.164 1.00 61.91  ? 409  TYR B CE2 1 
ATOM   9972  C  CZ  . TYR B 1 409 ? 149.547 131.364 216.410 1.00 61.91  ? 409  TYR B CZ  1 
ATOM   9973  O  OH  . TYR B 1 409 ? 150.413 130.390 216.849 1.00 61.91  ? 409  TYR B OH  1 
ATOM   9974  N  N   . GLN B 1 410 ? 145.969 136.579 212.335 1.00 59.35  ? 410  GLN B N   1 
ATOM   9975  C  CA  . GLN B 1 410 ? 144.847 137.112 211.580 1.00 59.35  ? 410  GLN B CA  1 
ATOM   9976  C  C   . GLN B 1 410 ? 144.765 136.447 210.208 1.00 59.35  ? 410  GLN B C   1 
ATOM   9977  O  O   . GLN B 1 410 ? 145.732 135.867 209.707 1.00 59.35  ? 410  GLN B O   1 
ATOM   9978  C  CB  . GLN B 1 410 ? 144.979 138.624 211.412 1.00 59.35  ? 410  GLN B CB  1 
ATOM   9979  C  CG  . GLN B 1 410 ? 145.967 139.027 210.332 1.00 59.35  ? 410  GLN B CG  1 
ATOM   9980  C  CD  . GLN B 1 410 ? 145.828 140.475 209.917 1.00 59.35  ? 410  GLN B CD  1 
ATOM   9981  O  OE1 . GLN B 1 410 ? 144.984 141.203 210.435 1.00 59.35  ? 410  GLN B OE1 1 
ATOM   9982  N  NE2 . GLN B 1 410 ? 146.662 140.902 208.978 1.00 59.35  ? 410  GLN B NE2 1 
ATOM   9983  N  N   . THR B 1 411 ? 143.583 136.535 209.598 1.00 62.26  ? 411  THR B N   1 
ATOM   9984  C  CA  . THR B 1 411 ? 143.373 136.040 208.246 1.00 62.26  ? 411  THR B CA  1 
ATOM   9985  C  C   . THR B 1 411 ? 142.713 137.063 207.335 1.00 62.26  ? 411  THR B C   1 
ATOM   9986  O  O   . THR B 1 411 ? 142.296 136.706 206.227 1.00 62.26  ? 411  THR B O   1 
ATOM   9987  C  CB  . THR B 1 411 ? 142.529 134.757 208.263 1.00 62.26  ? 411  THR B CB  1 
ATOM   9988  O  OG1 . THR B 1 411 ? 141.357 134.961 209.062 1.00 62.26  ? 411  THR B OG1 1 
ATOM   9989  C  CG2 . THR B 1 411 ? 143.333 133.594 208.824 1.00 62.26  ? 411  THR B CG2 1 
ATOM   9990  N  N   . GLY B 1 412 ? 142.603 138.317 207.763 1.00 57.25  ? 412  GLY B N   1 
ATOM   9991  C  CA  . GLY B 1 412 ? 142.029 139.358 206.942 1.00 57.25  ? 412  GLY B CA  1 
ATOM   9992  C  C   . GLY B 1 412 ? 143.047 139.961 205.994 1.00 57.25  ? 412  GLY B C   1 
ATOM   9993  O  O   . GLY B 1 412 ? 144.080 139.371 205.670 1.00 57.25  ? 412  GLY B O   1 
ATOM   9994  N  N   . LEU B 1 413 ? 142.734 141.170 205.539 1.00 54.48  ? 413  LEU B N   1 
ATOM   9995  C  CA  . LEU B 1 413 ? 143.633 141.888 204.647 1.00 54.48  ? 413  LEU B CA  1 
ATOM   9996  C  C   . LEU B 1 413 ? 144.918 142.268 205.371 1.00 54.48  ? 413  LEU B C   1 
ATOM   9997  O  O   . LEU B 1 413 ? 144.900 142.655 206.542 1.00 54.48  ? 413  LEU B O   1 
ATOM   9998  C  CB  . LEU B 1 413 ? 142.952 143.142 204.103 1.00 54.48  ? 413  LEU B CB  1 
ATOM   9999  C  CG  . LEU B 1 413 ? 142.038 142.970 202.892 1.00 54.48  ? 413  LEU B CG  1 
ATOM   10000 C  CD1 . LEU B 1 413 ? 141.592 144.328 202.383 1.00 54.48  ? 413  LEU B CD1 1 
ATOM   10001 C  CD2 . LEU B 1 413 ? 142.742 142.189 201.795 1.00 54.48  ? 413  LEU B CD2 1 
ATOM   10002 N  N   . LYS B 1 414 ? 146.038 142.152 204.665 1.00 56.39  ? 414  LYS B N   1 
ATOM   10003 C  CA  . LYS B 1 414 ? 147.311 142.592 205.213 1.00 56.39  ? 414  LYS B CA  1 
ATOM   10004 C  C   . LYS B 1 414 ? 147.323 144.107 205.375 1.00 56.39  ? 414  LYS B C   1 
ATOM   10005 O  O   . LYS B 1 414 ? 146.790 144.849 204.545 1.00 56.39  ? 414  LYS B O   1 
ATOM   10006 C  CB  . LYS B 1 414 ? 148.465 142.150 204.314 1.00 56.39  ? 414  LYS B CB  1 
ATOM   10007 C  CG  . LYS B 1 414 ? 148.651 140.644 204.237 1.00 56.39  ? 414  LYS B CG  1 
ATOM   10008 C  CD  . LYS B 1 414 ? 148.937 140.053 205.608 1.00 56.39  ? 414  LYS B CD  1 
ATOM   10009 C  CE  . LYS B 1 414 ? 150.289 140.505 206.136 1.00 56.39  ? 414  LYS B CE  1 
ATOM   10010 N  NZ  . LYS B 1 414 ? 150.582 139.922 207.474 1.00 56.39  ? 414  LYS B NZ  1 
ATOM   10011 N  N   . ASN B 1 415 ? 147.941 144.564 206.459 1.00 54.65  ? 415  ASN B N   1 
ATOM   10012 C  CA  . ASN B 1 415 ? 147.996 145.980 206.783 1.00 54.65  ? 415  ASN B CA  1 
ATOM   10013 C  C   . ASN B 1 415 ? 149.445 146.395 206.994 1.00 54.65  ? 415  ASN B C   1 
ATOM   10014 O  O   . ASN B 1 415 ? 150.317 145.568 207.273 1.00 54.65  ? 415  ASN B O   1 
ATOM   10015 C  CB  . ASN B 1 415 ? 147.164 146.301 208.033 1.00 54.65  ? 415  ASN B CB  1 
ATOM   10016 C  CG  . ASN B 1 415 ? 146.810 147.770 208.134 1.00 54.65  ? 415  ASN B CG  1 
ATOM   10017 O  OD1 . ASN B 1 415 ? 146.619 148.445 207.123 1.00 54.65  ? 415  ASN B OD1 1 
ATOM   10018 N  ND2 . ASN B 1 415 ? 146.720 148.274 209.359 1.00 54.65  ? 415  ASN B ND2 1 
ATOM   10019 N  N   . LEU B 1 416 ? 149.692 147.700 206.849 1.00 48.67  ? 416  LEU B N   1 
ATOM   10020 C  CA  . LEU B 1 416 ? 151.038 148.224 207.052 1.00 48.67  ? 416  LEU B CA  1 
ATOM   10021 C  C   . LEU B 1 416 ? 151.509 147.996 208.483 1.00 48.67  ? 416  LEU B C   1 
ATOM   10022 O  O   . LEU B 1 416 ? 152.675 147.653 208.714 1.00 48.67  ? 416  LEU B O   1 
ATOM   10023 C  CB  . LEU B 1 416 ? 151.082 149.708 206.680 1.00 48.67  ? 416  LEU B CB  1 
ATOM   10024 C  CG  . LEU B 1 416 ? 150.087 150.677 207.328 1.00 48.67  ? 416  LEU B CG  1 
ATOM   10025 C  CD1 . LEU B 1 416 ? 150.622 151.261 208.624 1.00 48.67  ? 416  LEU B CD1 1 
ATOM   10026 C  CD2 . LEU B 1 416 ? 149.715 151.787 206.357 1.00 48.67  ? 416  LEU B CD2 1 
ATOM   10027 N  N   . LEU B 1 417 ? 150.613 148.174 209.458 1.00 51.50  ? 417  LEU B N   1 
ATOM   10028 C  CA  . LEU B 1 417 ? 150.974 147.897 210.844 1.00 51.50  ? 417  LEU B CA  1 
ATOM   10029 C  C   . LEU B 1 417 ? 151.323 146.429 211.035 1.00 51.50  ? 417  LEU B C   1 
ATOM   10030 O  O   . LEU B 1 417 ? 152.274 146.103 211.752 1.00 51.50  ? 417  LEU B O   1 
ATOM   10031 C  CB  . LEU B 1 417 ? 149.838 148.302 211.783 1.00 51.50  ? 417  LEU B CB  1 
ATOM   10032 C  CG  . LEU B 1 417 ? 150.106 148.122 213.282 1.00 51.50  ? 417  LEU B CG  1 
ATOM   10033 C  CD1 . LEU B 1 417 ? 149.498 149.259 214.070 1.00 51.50  ? 417  LEU B CD1 1 
ATOM   10034 C  CD2 . LEU B 1 417 ? 149.565 146.794 213.794 1.00 51.50  ? 417  LEU B CD2 1 
ATOM   10035 N  N   . ASP B 1 418 ? 150.556 145.531 210.416 1.00 55.66  ? 418  ASP B N   1 
ATOM   10036 C  CA  . ASP B 1 418 ? 150.830 144.106 210.562 1.00 55.66  ? 418  ASP B CA  1 
ATOM   10037 C  C   . ASP B 1 418 ? 152.202 143.754 210.002 1.00 55.66  ? 418  ASP B C   1 
ATOM   10038 O  O   . ASP B 1 418 ? 152.976 143.031 210.640 1.00 55.66  ? 418  ASP B O   1 
ATOM   10039 C  CB  . ASP B 1 418 ? 149.740 143.290 209.866 1.00 55.66  ? 418  ASP B CB  1 
ATOM   10040 C  CG  . ASP B 1 418 ? 148.385 143.437 210.534 1.00 55.66  ? 418  ASP B CG  1 
ATOM   10041 O  OD1 . ASP B 1 418 ? 148.326 143.442 211.781 1.00 55.66  ? 418  ASP B OD1 1 
ATOM   10042 O  OD2 . ASP B 1 418 ? 147.374 143.545 209.809 1.00 55.66  ? 418  ASP B OD2 1 
ATOM   10043 N  N   . THR B 1 419 ? 152.526 144.273 208.815 1.00 55.71  ? 419  THR B N   1 
ATOM   10044 C  CA  . THR B 1 419 ? 153.830 144.007 208.219 1.00 55.71  ? 419  THR B CA  1 
ATOM   10045 C  C   . THR B 1 419 ? 154.955 144.584 209.069 1.00 55.71  ? 419  THR B C   1 
ATOM   10046 O  O   . THR B 1 419 ? 155.987 143.933 209.272 1.00 55.71  ? 419  THR B O   1 
ATOM   10047 C  CB  . THR B 1 419 ? 153.884 144.576 206.802 1.00 55.71  ? 419  THR B CB  1 
ATOM   10048 O  OG1 . THR B 1 419 ? 152.784 144.064 206.038 1.00 55.71  ? 419  THR B OG1 1 
ATOM   10049 C  CG2 . THR B 1 419 ? 155.188 144.192 206.124 1.00 55.71  ? 419  THR B CG2 1 
ATOM   10050 N  N   . ALA B 1 420 ? 154.774 145.807 209.576 1.00 56.70  ? 420  ALA B N   1 
ATOM   10051 C  CA  . ALA B 1 420 ? 155.811 146.422 210.397 1.00 56.70  ? 420  ALA B CA  1 
ATOM   10052 C  C   . ALA B 1 420 ? 156.032 145.644 211.687 1.00 56.70  ? 420  ALA B C   1 
ATOM   10053 O  O   . ALA B 1 420 ? 157.175 145.450 212.114 1.00 56.70  ? 420  ALA B O   1 
ATOM   10054 C  CB  . ALA B 1 420 ? 155.449 147.871 210.705 1.00 56.70  ? 420  ALA B CB  1 
ATOM   10055 N  N   . VAL B 1 421 ? 154.950 145.195 212.325 1.00 56.13  ? 421  VAL B N   1 
ATOM   10056 C  CA  . VAL B 1 421 ? 155.081 144.421 213.553 1.00 56.13  ? 421  VAL B CA  1 
ATOM   10057 C  C   . VAL B 1 421 ? 155.759 143.086 213.274 1.00 56.13  ? 421  VAL B C   1 
ATOM   10058 O  O   . VAL B 1 421 ? 156.623 142.643 214.040 1.00 56.13  ? 421  VAL B O   1 
ATOM   10059 C  CB  . VAL B 1 421 ? 153.704 144.238 214.217 1.00 56.13  ? 421  VAL B CB  1 
ATOM   10060 C  CG1 . VAL B 1 421 ? 153.794 143.238 215.347 1.00 56.13  ? 421  VAL B CG1 1 
ATOM   10061 C  CG2 . VAL B 1 421 ? 153.191 145.569 214.735 1.00 56.13  ? 421  VAL B CG2 1 
ATOM   10062 N  N   . LEU B 1 422 ? 155.386 142.424 212.174 1.00 58.56  ? 422  LEU B N   1 
ATOM   10063 C  CA  . LEU B 1 422 ? 156.028 141.160 211.827 1.00 58.56  ? 422  LEU B CA  1 
ATOM   10064 C  C   . LEU B 1 422 ? 157.516 141.338 211.554 1.00 58.56  ? 422  LEU B C   1 
ATOM   10065 O  O   . LEU B 1 422 ? 158.323 140.500 211.971 1.00 58.56  ? 422  LEU B O   1 
ATOM   10066 C  CB  . LEU B 1 422 ? 155.340 140.532 210.615 1.00 58.56  ? 422  LEU B CB  1 
ATOM   10067 C  CG  . LEU B 1 422 ? 153.948 139.947 210.848 1.00 58.56  ? 422  LEU B CG  1 
ATOM   10068 C  CD1 . LEU B 1 422 ? 153.421 139.294 209.581 1.00 58.56  ? 422  LEU B CD1 1 
ATOM   10069 C  CD2 . LEU B 1 422 ? 153.977 138.949 211.993 1.00 58.56  ? 422  LEU B CD2 1 
ATOM   10070 N  N   . GLU B 1 423 ? 157.898 142.412 210.864 1.00 63.85  ? 423  GLU B N   1 
ATOM   10071 C  CA  . GLU B 1 423 ? 159.303 142.650 210.556 1.00 63.85  ? 423  GLU B CA  1 
ATOM   10072 C  C   . GLU B 1 423 ? 160.110 143.104 211.764 1.00 63.85  ? 423  GLU B C   1 
ATOM   10073 O  O   . GLU B 1 423 ? 161.303 142.792 211.853 1.00 63.85  ? 423  GLU B O   1 
ATOM   10074 C  CB  . GLU B 1 423 ? 159.431 143.694 209.444 1.00 63.85  ? 423  GLU B CB  1 
ATOM   10075 C  CG  . GLU B 1 423 ? 159.261 143.132 208.044 1.00 63.85  ? 423  GLU B CG  1 
ATOM   10076 C  CD  . GLU B 1 423 ? 159.033 144.213 207.008 1.00 63.85  ? 423  GLU B CD  1 
ATOM   10077 O  OE1 . GLU B 1 423 ? 159.411 145.375 207.268 1.00 63.85  ? 423  GLU B OE1 1 
ATOM   10078 O  OE2 . GLU B 1 423 ? 158.478 143.902 205.934 1.00 63.85  ? 423  GLU B OE2 1 
ATOM   10079 N  N   . GLY B 1 424 ? 159.493 143.830 212.693 1.00 66.78  ? 424  GLY B N   1 
ATOM   10080 C  CA  . GLY B 1 424 ? 160.189 144.355 213.849 1.00 66.78  ? 424  GLY B CA  1 
ATOM   10081 C  C   . GLY B 1 424 ? 160.366 143.400 215.003 1.00 66.78  ? 424  GLY B C   1 
ATOM   10082 O  O   . GLY B 1 424 ? 160.997 143.761 216.000 1.00 66.78  ? 424  GLY B O   1 
ATOM   10083 N  N   . THR B 1 425 ? 159.826 142.190 214.905 1.00 71.84  ? 425  THR B N   1 
ATOM   10084 C  CA  . THR B 1 425 ? 159.970 141.178 215.942 1.00 71.84  ? 425  THR B CA  1 
ATOM   10085 C  C   . THR B 1 425 ? 161.101 140.232 215.566 1.00 71.84  ? 425  THR B C   1 
ATOM   10086 O  O   . THR B 1 425 ? 161.158 139.747 214.431 1.00 71.84  ? 425  THR B O   1 
ATOM   10087 C  CB  . THR B 1 425 ? 158.669 140.396 216.132 1.00 71.84  ? 425  THR B CB  1 
ATOM   10088 O  OG1 . THR B 1 425 ? 157.567 141.308 216.200 1.00 71.84  ? 425  THR B OG1 1 
ATOM   10089 C  CG2 . THR B 1 425 ? 158.722 139.580 217.412 1.00 71.84  ? 425  THR B CG2 1 
ATOM   10090 N  N   . ASP B 1 426 ? 161.999 139.978 216.515 1.00 80.13  ? 426  ASP B N   1 
ATOM   10091 C  CA  . ASP B 1 426 ? 163.134 139.108 216.255 1.00 80.13  ? 426  ASP B CA  1 
ATOM   10092 C  C   . ASP B 1 426 ? 162.665 137.682 215.978 1.00 80.13  ? 426  ASP B C   1 
ATOM   10093 O  O   . ASP B 1 426 ? 161.612 137.240 216.446 1.00 80.13  ? 426  ASP B O   1 
ATOM   10094 C  CB  . ASP B 1 426 ? 164.109 139.128 217.432 1.00 80.13  ? 426  ASP B CB  1 
ATOM   10095 C  CG  . ASP B 1 426 ? 163.413 138.961 218.766 1.00 80.13  ? 426  ASP B CG  1 
ATOM   10096 O  OD1 . ASP B 1 426 ? 162.282 139.470 218.913 1.00 80.13  ? 426  ASP B OD1 1 
ATOM   10097 O  OD2 . ASP B 1 426 ? 163.996 138.323 219.668 1.00 80.13  ? 426  ASP B OD2 1 
ATOM   10098 N  N   . GLU B 1 427 ? 163.472 136.961 215.195 1.00 83.80  ? 427  GLU B N   1 
ATOM   10099 C  CA  . GLU B 1 427 ? 163.083 135.626 214.751 1.00 83.80  ? 427  GLU B CA  1 
ATOM   10100 C  C   . GLU B 1 427 ? 162.920 134.668 215.925 1.00 83.80  ? 427  GLU B C   1 
ATOM   10101 O  O   . GLU B 1 427 ? 162.011 133.830 215.927 1.00 83.80  ? 427  GLU B O   1 
ATOM   10102 C  CB  . GLU B 1 427 ? 164.112 135.085 213.758 1.00 83.80  ? 427  GLU B CB  1 
ATOM   10103 C  CG  . GLU B 1 427 ? 163.788 135.392 212.306 1.00 83.80  ? 427  GLU B CG  1 
ATOM   10104 C  CD  . GLU B 1 427 ? 162.652 134.542 211.772 1.00 83.80  ? 427  GLU B CD  1 
ATOM   10105 O  OE1 . GLU B 1 427 ? 162.570 133.354 212.148 1.00 83.80  ? 427  GLU B OE1 1 
ATOM   10106 O  OE2 . GLU B 1 427 ? 161.841 135.062 210.978 1.00 83.80  ? 427  GLU B OE2 1 
ATOM   10107 N  N   . GLU B 1 428 ? 163.795 134.770 216.928 1.00 85.06  ? 428  GLU B N   1 
ATOM   10108 C  CA  . GLU B 1 428 ? 163.731 133.855 218.064 1.00 85.06  ? 428  GLU B CA  1 
ATOM   10109 C  C   . GLU B 1 428 ? 162.420 134.009 218.826 1.00 85.06  ? 428  GLU B C   1 
ATOM   10110 O  O   . GLU B 1 428 ? 161.711 133.026 219.072 1.00 85.06  ? 428  GLU B O   1 
ATOM   10111 C  CB  . GLU B 1 428 ? 164.925 134.091 218.990 1.00 85.06  ? 428  GLU B CB  1 
ATOM   10112 C  CG  . GLU B 1 428 ? 164.931 133.218 220.236 1.00 85.06  ? 428  GLU B CG  1 
ATOM   10113 C  CD  . GLU B 1 428 ? 165.049 131.739 219.918 1.00 85.06  ? 428  GLU B CD  1 
ATOM   10114 O  OE1 . GLU B 1 428 ? 165.651 131.395 218.879 1.00 85.06  ? 428  GLU B OE1 1 
ATOM   10115 O  OE2 . GLU B 1 428 ? 164.538 130.919 220.710 1.00 85.06  ? 428  GLU B OE2 1 
ATOM   10116 N  N   . SER B 1 429 ? 162.075 135.243 219.202 1.00 78.60  ? 429  SER B N   1 
ATOM   10117 C  CA  . SER B 1 429 ? 160.834 135.467 219.936 1.00 78.60  ? 429  SER B CA  1 
ATOM   10118 C  C   . SER B 1 429 ? 159.619 135.153 219.075 1.00 78.60  ? 429  SER B C   1 
ATOM   10119 O  O   . SER B 1 429 ? 158.617 134.628 219.574 1.00 78.60  ? 429  SER B O   1 
ATOM   10120 C  CB  . SER B 1 429 ? 160.773 136.907 220.443 1.00 78.60  ? 429  SER B CB  1 
ATOM   10121 O  OG  . SER B 1 429 ? 160.682 137.820 219.364 1.00 78.60  ? 429  SER B OG  1 
ATOM   10122 N  N   . ALA B 1 430 ? 159.687 135.470 217.780 1.00 75.35  ? 430  ALA B N   1 
ATOM   10123 C  CA  . ALA B 1 430 ? 158.568 135.184 216.888 1.00 75.35  ? 430  ALA B CA  1 
ATOM   10124 C  C   . ALA B 1 430 ? 158.307 133.686 216.798 1.00 75.35  ? 430  ALA B C   1 
ATOM   10125 O  O   . ALA B 1 430 ? 157.158 133.238 216.891 1.00 75.35  ? 430  ALA B O   1 
ATOM   10126 C  CB  . ALA B 1 430 ? 158.840 135.770 215.502 1.00 75.35  ? 430  ALA B CB  1 
ATOM   10127 N  N   . ARG B 1 431 ? 159.366 132.890 216.631 1.00 80.43  ? 431  ARG B N   1 
ATOM   10128 C  CA  . ARG B 1 431 ? 159.182 131.445 216.558 1.00 80.43  ? 431  ARG B CA  1 
ATOM   10129 C  C   . ARG B 1 431 ? 158.771 130.865 217.906 1.00 80.43  ? 431  ARG B C   1 
ATOM   10130 O  O   . ARG B 1 431 ? 157.991 129.905 217.951 1.00 80.43  ? 431  ARG B O   1 
ATOM   10131 C  CB  . ARG B 1 431 ? 160.453 130.771 216.032 1.00 80.43  ? 431  ARG B CB  1 
ATOM   10132 C  CG  . ARG B 1 431 ? 161.571 130.604 217.047 1.00 80.43  ? 431  ARG B CG  1 
ATOM   10133 C  CD  . ARG B 1 431 ? 162.788 129.943 216.421 1.00 80.43  ? 431  ARG B CD  1 
ATOM   10134 N  NE  . ARG B 1 431 ? 163.530 130.863 215.567 1.00 80.43  ? 431  ARG B NE  1 
ATOM   10135 C  CZ  . ARG B 1 431 ? 163.627 130.748 214.250 1.00 80.43  ? 431  ARG B CZ  1 
ATOM   10136 N  NH1 . ARG B 1 431 ? 163.040 129.759 213.597 1.00 80.43  ? 431  ARG B NH1 1 
ATOM   10137 N  NH2 . ARG B 1 431 ? 164.332 131.649 213.570 1.00 80.43  ? 431  ARG B NH2 1 
ATOM   10138 N  N   . SER B 1 432 ? 159.260 131.438 219.010 1.00 74.74  ? 432  SER B N   1 
ATOM   10139 C  CA  . SER B 1 432 ? 158.823 130.984 220.325 1.00 74.74  ? 432  SER B CA  1 
ATOM   10140 C  C   . SER B 1 432 ? 157.331 131.220 220.518 1.00 74.74  ? 432  SER B C   1 
ATOM   10141 O  O   . SER B 1 432 ? 156.615 130.345 221.015 1.00 74.74  ? 432  SER B O   1 
ATOM   10142 C  CB  . SER B 1 432 ? 159.624 131.689 221.419 1.00 74.74  ? 432  SER B CB  1 
ATOM   10143 O  OG  . SER B 1 432 ? 158.923 131.676 222.650 1.00 74.74  ? 432  SER B OG  1 
ATOM   10144 N  N   . LEU B 1 433 ? 156.844 132.398 220.122 1.00 68.68  ? 433  LEU B N   1 
ATOM   10145 C  CA  . LEU B 1 433 ? 155.415 132.679 220.223 1.00 68.68  ? 433  LEU B CA  1 
ATOM   10146 C  C   . LEU B 1 433 ? 154.608 131.790 219.284 1.00 68.68  ? 433  LEU B C   1 
ATOM   10147 O  O   . LEU B 1 433 ? 153.522 131.322 219.647 1.00 68.68  ? 433  LEU B O   1 
ATOM   10148 C  CB  . LEU B 1 433 ? 155.148 134.154 219.928 1.00 68.68  ? 433  LEU B CB  1 
ATOM   10149 C  CG  . LEU B 1 433 ? 155.446 135.137 221.061 1.00 68.68  ? 433  LEU B CG  1 
ATOM   10150 C  CD1 . LEU B 1 433 ? 155.250 136.569 220.593 1.00 68.68  ? 433  LEU B CD1 1 
ATOM   10151 C  CD2 . LEU B 1 433 ? 154.574 134.844 222.269 1.00 68.68  ? 433  LEU B CD2 1 
ATOM   10152 N  N   . ALA B 1 434 ? 155.119 131.550 218.074 1.00 74.17  ? 434  ALA B N   1 
ATOM   10153 C  CA  . ALA B 1 434 ? 154.403 130.706 217.122 1.00 74.17  ? 434  ALA B CA  1 
ATOM   10154 C  C   . ALA B 1 434 ? 154.266 129.279 217.637 1.00 74.17  ? 434  ALA B C   1 
ATOM   10155 O  O   . ALA B 1 434 ? 153.195 128.671 217.527 1.00 74.17  ? 434  ALA B O   1 
ATOM   10156 C  CB  . ALA B 1 434 ? 155.112 130.723 215.768 1.00 74.17  ? 434  ALA B CB  1 
ATOM   10157 N  N   . SER B 1 435 ? 155.339 128.726 218.206 1.00 77.28  ? 435  SER B N   1 
ATOM   10158 C  CA  . SER B 1 435 ? 155.282 127.378 218.756 1.00 77.28  ? 435  SER B CA  1 
ATOM   10159 C  C   . SER B 1 435 ? 154.636 127.335 220.134 1.00 77.28  ? 435  SER B C   1 
ATOM   10160 O  O   . SER B 1 435 ? 154.338 126.243 220.630 1.00 77.28  ? 435  SER B O   1 
ATOM   10161 C  CB  . SER B 1 435 ? 156.688 126.780 218.828 1.00 77.28  ? 435  SER B CB  1 
ATOM   10162 O  OG  . SER B 1 435 ? 157.304 126.774 217.553 1.00 77.28  ? 435  SER B OG  1 
ATOM   10163 N  N   . ARG B 1 436 ? 154.416 128.491 220.757 1.00 79.16  ? 436  ARG B N   1 
ATOM   10164 C  CA  . ARG B 1 436 ? 153.845 128.554 222.094 1.00 79.16  ? 436  ARG B CA  1 
ATOM   10165 C  C   . ARG B 1 436 ? 152.351 128.846 222.082 1.00 79.16  ? 436  ARG B C   1 
ATOM   10166 O  O   . ARG B 1 436 ? 151.655 128.488 223.039 1.00 79.16  ? 436  ARG B O   1 
ATOM   10167 C  CB  . ARG B 1 436 ? 154.581 129.625 222.911 1.00 79.16  ? 436  ARG B CB  1 
ATOM   10168 C  CG  . ARG B 1 436 ? 154.421 129.535 224.423 1.00 79.16  ? 436  ARG B CG  1 
ATOM   10169 C  CD  . ARG B 1 436 ? 153.307 130.423 224.947 1.00 79.16  ? 436  ARG B CD  1 
ATOM   10170 N  NE  . ARG B 1 436 ? 153.343 130.521 226.401 1.00 79.16  ? 436  ARG B NE  1 
ATOM   10171 C  CZ  . ARG B 1 436 ? 152.864 129.603 227.229 1.00 79.16  ? 436  ARG B CZ  1 
ATOM   10172 N  NH1 . ARG B 1 436 ? 152.328 128.480 226.780 1.00 79.16  ? 436  ARG B NH1 1 
ATOM   10173 N  NH2 . ARG B 1 436 ? 152.934 129.812 228.540 1.00 79.16  ? 436  ARG B NH2 1 
ATOM   10174 N  N   . TRP B 1 437 ? 151.843 129.469 221.021 1.00 75.64  ? 437  TRP B N   1 
ATOM   10175 C  CA  . TRP B 1 437 ? 150.444 129.853 220.916 1.00 75.64  ? 437  TRP B CA  1 
ATOM   10176 C  C   . TRP B 1 437 ? 149.827 129.226 219.672 1.00 75.64  ? 437  TRP B C   1 
ATOM   10177 O  O   . TRP B 1 437 ? 150.514 128.976 218.677 1.00 75.64  ? 437  TRP B O   1 
ATOM   10178 C  CB  . TRP B 1 437 ? 150.295 131.378 220.850 1.00 75.64  ? 437  TRP B CB  1 
ATOM   10179 C  CG  . TRP B 1 437 ? 150.647 132.078 222.125 1.00 75.64  ? 437  TRP B CG  1 
ATOM   10180 C  CD1 . TRP B 1 437 ? 151.849 132.638 222.445 1.00 75.64  ? 437  TRP B CD1 1 
ATOM   10181 C  CD2 . TRP B 1 437 ? 149.786 132.309 223.246 1.00 75.64  ? 437  TRP B CD2 1 
ATOM   10182 N  NE1 . TRP B 1 437 ? 151.792 133.196 223.699 1.00 75.64  ? 437  TRP B NE1 1 
ATOM   10183 C  CE2 . TRP B 1 437 ? 150.536 133.008 224.211 1.00 75.64  ? 437  TRP B CE2 1 
ATOM   10184 C  CE3 . TRP B 1 437 ? 148.455 131.989 223.528 1.00 75.64  ? 437  TRP B CE3 1 
ATOM   10185 C  CZ2 . TRP B 1 437 ? 150.000 133.392 225.438 1.00 75.64  ? 437  TRP B CZ2 1 
ATOM   10186 C  CZ3 . TRP B 1 437 ? 147.925 132.372 224.746 1.00 75.64  ? 437  TRP B CZ3 1 
ATOM   10187 C  CH2 . TRP B 1 437 ? 148.697 133.065 225.686 1.00 75.64  ? 437  TRP B CH2 1 
ATOM   10188 N  N   . GLN B 1 438 ? 148.521 128.972 219.736 1.00 76.39  ? 438  GLN B N   1 
ATOM   10189 C  CA  . GLN B 1 438 ? 147.776 128.428 218.612 1.00 76.39  ? 438  GLN B CA  1 
ATOM   10190 C  C   . GLN B 1 438 ? 146.455 129.169 218.462 1.00 76.39  ? 438  GLN B C   1 
ATOM   10191 O  O   . GLN B 1 438 ? 145.799 129.513 219.449 1.00 76.39  ? 438  GLN B O   1 
ATOM   10192 C  CB  . GLN B 1 438 ? 147.528 126.920 218.778 1.00 76.39  ? 438  GLN B CB  1 
ATOM   10193 C  CG  . GLN B 1 438 ? 146.613 126.553 219.933 1.00 76.39  ? 438  GLN B CG  1 
ATOM   10194 C  CD  . GLN B 1 438 ? 146.400 125.058 220.053 1.00 76.39  ? 438  GLN B CD  1 
ATOM   10195 O  OE1 . GLN B 1 438 ? 146.908 124.280 219.246 1.00 76.39  ? 438  GLN B OE1 1 
ATOM   10196 N  NE2 . GLN B 1 438 ? 145.644 124.648 221.066 1.00 76.39  ? 438  GLN B NE2 1 
ATOM   10197 N  N   . LYS B 1 439 ? 146.075 129.418 217.213 1.00 67.92  ? 439  LYS B N   1 
ATOM   10198 C  CA  . LYS B 1 439 ? 144.861 130.165 216.916 1.00 67.92  ? 439  LYS B CA  1 
ATOM   10199 C  C   . LYS B 1 439 ? 143.621 129.311 217.151 1.00 67.92  ? 439  LYS B C   1 
ATOM   10200 O  O   . LYS B 1 439 ? 143.619 128.099 216.918 1.00 67.92  ? 439  LYS B O   1 
ATOM   10201 C  CB  . LYS B 1 439 ? 144.881 130.660 215.469 1.00 67.92  ? 439  LYS B CB  1 
ATOM   10202 C  CG  . LYS B 1 439 ? 143.754 131.617 215.120 1.00 67.92  ? 439  LYS B CG  1 
ATOM   10203 C  CD  . LYS B 1 439 ? 143.564 131.727 213.618 1.00 67.92  ? 439  LYS B CD  1 
ATOM   10204 C  CE  . LYS B 1 439 ? 142.285 132.476 213.285 1.00 67.92  ? 439  LYS B CE  1 
ATOM   10205 N  NZ  . LYS B 1 439 ? 142.405 133.255 212.024 1.00 67.92  ? 439  LYS B NZ  1 
ATOM   10206 N  N   . ILE B 1 440 ? 142.555 129.961 217.620 1.00 68.32  ? 440  ILE B N   1 
ATOM   10207 C  CA  . ILE B 1 440 ? 141.251 129.332 217.793 1.00 68.32  ? 440  ILE B CA  1 
ATOM   10208 C  C   . ILE B 1 440 ? 140.179 130.033 216.968 1.00 68.32  ? 440  ILE B C   1 
ATOM   10209 O  O   . ILE B 1 440 ? 139.530 129.414 216.118 1.00 68.32  ? 440  ILE B O   1 
ATOM   10210 C  CB  . ILE B 1 440 ? 140.841 129.277 219.280 1.00 68.32  ? 440  ILE B CB  1 
ATOM   10211 C  CG1 . ILE B 1 440 ? 141.723 128.294 220.045 1.00 68.32  ? 440  ILE B CG1 1 
ATOM   10212 C  CG2 . ILE B 1 440 ? 139.375 128.898 219.417 1.00 68.32  ? 440  ILE B CG2 1 
ATOM   10213 C  CD1 . ILE B 1 440 ? 141.459 128.293 221.525 1.00 68.32  ? 440  ILE B CD1 1 
ATOM   10214 N  N   . ASP B 1 441 ? 139.975 131.327 217.205 1.00 69.34  ? 441  ASP B N   1 
ATOM   10215 C  CA  . ASP B 1 441 ? 138.894 132.042 216.540 1.00 69.34  ? 441  ASP B CA  1 
ATOM   10216 C  C   . ASP B 1 441 ? 139.365 133.437 216.158 1.00 69.34  ? 441  ASP B C   1 
ATOM   10217 O  O   . ASP B 1 441 ? 140.403 133.914 216.618 1.00 69.34  ? 441  ASP B O   1 
ATOM   10218 C  CB  . ASP B 1 441 ? 137.644 132.111 217.423 1.00 69.34  ? 441  ASP B CB  1 
ATOM   10219 C  CG  . ASP B 1 441 ? 136.360 132.118 216.616 1.00 69.34  ? 441  ASP B CG  1 
ATOM   10220 O  OD1 . ASP B 1 441 ? 136.345 131.528 215.515 1.00 69.34  ? 441  ASP B OD1 1 
ATOM   10221 O  OD2 . ASP B 1 441 ? 135.365 132.710 217.084 1.00 69.34  ? 441  ASP B OD2 1 
ATOM   10222 N  N   . GLU B 1 442 ? 138.577 134.096 215.311 1.00 63.71  ? 442  GLU B N   1 
ATOM   10223 C  CA  . GLU B 1 442 ? 138.904 135.434 214.840 1.00 63.71  ? 442  GLU B CA  1 
ATOM   10224 C  C   . GLU B 1 442 ? 137.629 136.244 214.671 1.00 63.71  ? 442  GLU B C   1 
ATOM   10225 O  O   . GLU B 1 442 ? 136.655 135.761 214.086 1.00 63.71  ? 442  GLU B O   1 
ATOM   10226 C  CB  . GLU B 1 442 ? 139.672 135.376 213.515 1.00 63.71  ? 442  GLU B CB  1 
ATOM   10227 C  CG  . GLU B 1 442 ? 140.215 136.715 213.051 1.00 63.71  ? 442  GLU B CG  1 
ATOM   10228 C  CD  . GLU B 1 442 ? 140.821 136.640 211.666 1.00 63.71  ? 442  GLU B CD  1 
ATOM   10229 O  OE1 . GLU B 1 442 ? 141.106 135.515 211.204 1.00 63.71  ? 442  GLU B OE1 1 
ATOM   10230 O  OE2 . GLU B 1 442 ? 141.011 137.702 211.038 1.00 63.71  ? 442  GLU B OE2 1 
ATOM   10231 N  N   . ILE B 1 443 ? 137.640 137.470 215.185 1.00 63.13  ? 443  ILE B N   1 
ATOM   10232 C  CA  . ILE B 1 443 ? 136.537 138.412 215.022 1.00 63.13  ? 443  ILE B CA  1 
ATOM   10233 C  C   . ILE B 1 443 ? 137.020 139.504 214.075 1.00 63.13  ? 443  ILE B C   1 
ATOM   10234 O  O   . ILE B 1 443 ? 137.849 140.346 214.464 1.00 63.13  ? 443  ILE B O   1 
ATOM   10235 C  CB  . ILE B 1 443 ? 136.083 138.983 216.373 1.00 63.13  ? 443  ILE B CB  1 
ATOM   10236 C  CG1 . ILE B 1 443 ? 135.992 137.866 217.413 1.00 63.13  ? 443  ILE B CG1 1 
ATOM   10237 C  CG2 . ILE B 1 443 ? 134.730 139.650 216.238 1.00 63.13  ? 443  ILE B CG2 1 
ATOM   10238 C  CD1 . ILE B 1 443 ? 135.879 138.365 218.834 1.00 63.13  ? 443  ILE B CD1 1 
ATOM   10239 N  N   . PRO B 1 444 ? 136.540 139.521 212.826 1.00 59.21  ? 444  PRO B N   1 
ATOM   10240 C  CA  . PRO B 1 444 ? 137.134 140.393 211.803 1.00 59.21  ? 444  PRO B CA  1 
ATOM   10241 C  C   . PRO B 1 444 ? 136.871 141.873 212.021 1.00 59.21  ? 444  PRO B C   1 
ATOM   10242 O  O   . PRO B 1 444 ? 136.255 142.275 213.012 1.00 59.21  ? 444  PRO B O   1 
ATOM   10243 C  CB  . PRO B 1 444 ? 136.475 139.904 210.506 1.00 59.21  ? 444  PRO B CB  1 
ATOM   10244 C  CG  . PRO B 1 444 ? 135.976 138.528 210.823 1.00 59.21  ? 444  PRO B CG  1 
ATOM   10245 C  CD  . PRO B 1 444 ? 135.544 138.606 212.249 1.00 59.21  ? 444  PRO B CD  1 
ATOM   10246 N  N   . PHE B 1 445 ? 137.338 142.689 211.080 1.00 64.35  ? 445  PHE B N   1 
ATOM   10247 C  CA  . PHE B 1 445 ? 137.216 144.134 211.184 1.00 64.35  ? 445  PHE B CA  1 
ATOM   10248 C  C   . PHE B 1 445 ? 135.920 144.613 210.543 1.00 64.35  ? 445  PHE B C   1 
ATOM   10249 O  O   . PHE B 1 445 ? 135.565 144.197 209.436 1.00 64.35  ? 445  PHE B O   1 
ATOM   10250 C  CB  . PHE B 1 445 ? 138.417 144.808 210.518 1.00 64.35  ? 445  PHE B CB  1 
ATOM   10251 C  CG  . PHE B 1 445 ? 138.389 146.308 210.577 1.00 64.35  ? 445  PHE B CG  1 
ATOM   10252 C  CD1 . PHE B 1 445 ? 138.949 146.981 211.649 1.00 64.35  ? 445  PHE B CD1 1 
ATOM   10253 C  CD2 . PHE B 1 445 ? 137.825 147.047 209.550 1.00 64.35  ? 445  PHE B CD2 1 
ATOM   10254 C  CE1 . PHE B 1 445 ? 138.934 148.360 211.703 1.00 64.35  ? 445  PHE B CE1 1 
ATOM   10255 C  CE2 . PHE B 1 445 ? 137.806 148.426 209.599 1.00 64.35  ? 445  PHE B CE2 1 
ATOM   10256 C  CZ  . PHE B 1 445 ? 138.361 149.083 210.677 1.00 64.35  ? 445  PHE B CZ  1 
ATOM   10257 N  N   . ASP B 1 446 ? 135.214 145.492 211.250 1.00 68.48  ? 446  ASP B N   1 
ATOM   10258 C  CA  . ASP B 1 446 ? 134.011 146.130 210.736 1.00 68.48  ? 446  ASP B CA  1 
ATOM   10259 C  C   . ASP B 1 446 ? 133.926 147.540 211.301 1.00 68.48  ? 446  ASP B C   1 
ATOM   10260 O  O   . ASP B 1 446 ? 134.439 147.828 212.384 1.00 68.48  ? 446  ASP B O   1 
ATOM   10261 C  CB  . ASP B 1 446 ? 132.750 145.330 211.083 1.00 68.48  ? 446  ASP B CB  1 
ATOM   10262 C  CG  . ASP B 1 446 ? 132.717 144.902 212.532 1.00 68.48  ? 446  ASP B CG  1 
ATOM   10263 O  OD1 . ASP B 1 446 ? 133.762 145.012 213.204 1.00 68.48  ? 446  ASP B OD1 1 
ATOM   10264 O  OD2 . ASP B 1 446 ? 131.647 144.456 212.997 1.00 68.48  ? 446  ASP B OD2 1 
ATOM   10265 N  N   . PHE B 1 447 ? 133.258 148.420 210.556 1.00 71.32  ? 447  PHE B N   1 
ATOM   10266 C  CA  . PHE B 1 447 ? 133.275 149.843 210.870 1.00 71.32  ? 447  PHE B CA  1 
ATOM   10267 C  C   . PHE B 1 447 ? 132.345 150.234 212.011 1.00 71.32  ? 447  PHE B C   1 
ATOM   10268 O  O   . PHE B 1 447 ? 132.456 151.358 212.512 1.00 71.32  ? 447  PHE B O   1 
ATOM   10269 C  CB  . PHE B 1 447 ? 132.928 150.655 209.621 1.00 71.32  ? 447  PHE B CB  1 
ATOM   10270 C  CG  . PHE B 1 447 ? 134.055 150.751 208.638 1.00 71.32  ? 447  PHE B CG  1 
ATOM   10271 C  CD1 . PHE B 1 447 ? 134.962 151.795 208.706 1.00 71.32  ? 447  PHE B CD1 1 
ATOM   10272 C  CD2 . PHE B 1 447 ? 134.219 149.790 207.656 1.00 71.32  ? 447  PHE B CD2 1 
ATOM   10273 C  CE1 . PHE B 1 447 ? 136.006 151.885 207.807 1.00 71.32  ? 447  PHE B CE1 1 
ATOM   10274 C  CE2 . PHE B 1 447 ? 135.261 149.874 206.755 1.00 71.32  ? 447  PHE B CE2 1 
ATOM   10275 C  CZ  . PHE B 1 447 ? 136.156 150.923 206.829 1.00 71.32  ? 447  PHE B CZ  1 
ATOM   10276 N  N   . GLU B 1 448 ? 131.435 149.355 212.435 1.00 75.81  ? 448  GLU B N   1 
ATOM   10277 C  CA  . GLU B 1 448 ? 130.596 149.686 213.582 1.00 75.81  ? 448  GLU B CA  1 
ATOM   10278 C  C   . GLU B 1 448 ? 131.408 149.759 214.869 1.00 75.81  ? 448  GLU B C   1 
ATOM   10279 O  O   . GLU B 1 448 ? 131.065 150.529 215.773 1.00 75.81  ? 448  GLU B O   1 
ATOM   10280 C  CB  . GLU B 1 448 ? 129.459 148.675 213.724 1.00 75.81  ? 448  GLU B CB  1 
ATOM   10281 C  CG  . GLU B 1 448 ? 128.269 148.961 212.822 1.00 75.81  ? 448  GLU B CG  1 
ATOM   10282 C  CD  . GLU B 1 448 ? 127.015 148.227 213.258 1.00 75.81  ? 448  GLU B CD  1 
ATOM   10283 O  OE1 . GLU B 1 448 ? 126.837 148.024 214.477 1.00 75.81  ? 448  GLU B OE1 1 
ATOM   10284 O  OE2 . GLU B 1 448 ? 126.200 147.868 212.383 1.00 75.81  ? 448  GLU B OE2 1 
ATOM   10285 N  N   . ARG B 1 449 ? 132.479 148.977 214.971 1.00 65.11  ? 449  ARG B N   1 
ATOM   10286 C  CA  . ARG B 1 449 ? 133.336 148.983 216.148 1.00 65.11  ? 449  ARG B CA  1 
ATOM   10287 C  C   . ARG B 1 449 ? 134.795 149.277 215.841 1.00 65.11  ? 449  ARG B C   1 
ATOM   10288 O  O   . ARG B 1 449 ? 135.531 149.663 216.751 1.00 65.11  ? 449  ARG B O   1 
ATOM   10289 C  CB  . ARG B 1 449 ? 133.252 147.636 216.879 1.00 65.11  ? 449  ARG B CB  1 
ATOM   10290 C  CG  . ARG B 1 449 ? 133.741 146.474 216.045 1.00 65.11  ? 449  ARG B CG  1 
ATOM   10291 C  CD  . ARG B 1 449 ? 133.014 145.185 216.376 1.00 65.11  ? 449  ARG B CD  1 
ATOM   10292 N  NE  . ARG B 1 449 ? 133.540 144.071 215.598 1.00 65.11  ? 449  ARG B NE  1 
ATOM   10293 C  CZ  . ARG B 1 449 ? 134.738 143.531 215.773 1.00 65.11  ? 449  ARG B CZ  1 
ATOM   10294 N  NH1 . ARG B 1 449 ? 135.548 143.940 216.736 1.00 65.11  ? 449  ARG B NH1 1 
ATOM   10295 N  NH2 . ARG B 1 449 ? 135.134 142.556 214.961 1.00 65.11  ? 449  ARG B NH2 1 
ATOM   10296 N  N   . ARG B 1 450 ? 135.235 149.087 214.596 1.00 63.25  ? 450  ARG B N   1 
ATOM   10297 C  CA  . ARG B 1 450 ? 136.587 149.404 214.144 1.00 63.25  ? 450  ARG B CA  1 
ATOM   10298 C  C   . ARG B 1 450 ? 137.669 148.711 214.966 1.00 63.25  ? 450  ARG B C   1 
ATOM   10299 O  O   . ARG B 1 450 ? 138.733 149.289 215.204 1.00 63.25  ? 450  ARG B O   1 
ATOM   10300 C  CB  . ARG B 1 450 ? 136.820 150.919 214.130 1.00 63.25  ? 450  ARG B CB  1 
ATOM   10301 C  CG  . ARG B 1 450 ? 135.888 151.659 213.182 1.00 63.25  ? 450  ARG B CG  1 
ATOM   10302 C  CD  . ARG B 1 450 ? 135.555 153.054 213.682 1.00 63.25  ? 450  ARG B CD  1 
ATOM   10303 N  NE  . ARG B 1 450 ? 136.709 153.944 213.635 1.00 63.25  ? 450  ARG B NE  1 
ATOM   10304 C  CZ  . ARG B 1 450 ? 136.783 155.031 212.879 1.00 63.25  ? 450  ARG B CZ  1 
ATOM   10305 N  NH1 . ARG B 1 450 ? 135.786 155.392 212.089 1.00 63.25  ? 450  ARG B NH1 1 
ATOM   10306 N  NH2 . ARG B 1 450 ? 137.885 155.774 212.918 1.00 63.25  ? 450  ARG B NH2 1 
ATOM   10307 N  N   . ARG B 1 451 ? 137.419 147.481 215.406 1.00 59.91  ? 451  ARG B N   1 
ATOM   10308 C  CA  . ARG B 1 451 ? 138.374 146.701 216.180 1.00 59.91  ? 451  ARG B CA  1 
ATOM   10309 C  C   . ARG B 1 451 ? 138.493 145.308 215.580 1.00 59.91  ? 451  ARG B C   1 
ATOM   10310 O  O   . ARG B 1 451 ? 137.498 144.733 215.129 1.00 59.91  ? 451  ARG B O   1 
ATOM   10311 C  CB  . ARG B 1 451 ? 137.939 146.592 217.643 1.00 59.91  ? 451  ARG B CB  1 
ATOM   10312 C  CG  . ARG B 1 451 ? 137.882 147.913 218.385 1.00 59.91  ? 451  ARG B CG  1 
ATOM   10313 C  CD  . ARG B 1 451 ? 137.591 147.690 219.859 1.00 59.91  ? 451  ARG B CD  1 
ATOM   10314 N  NE  . ARG B 1 451 ? 136.302 147.039 220.067 1.00 59.91  ? 451  ARG B NE  1 
ATOM   10315 C  CZ  . ARG B 1 451 ? 135.148 147.682 220.183 1.00 59.91  ? 451  ARG B CZ  1 
ATOM   10316 N  NH1 . ARG B 1 451 ? 135.083 149.002 220.122 1.00 59.91  ? 451  ARG B NH1 1 
ATOM   10317 N  NH2 . ARG B 1 451 ? 134.032 146.983 220.367 1.00 59.91  ? 451  ARG B NH2 1 
ATOM   10318 N  N   . MET B 1 452 ? 139.705 144.764 215.569 1.00 57.07  ? 452  MET B N   1 
ATOM   10319 C  CA  . MET B 1 452 ? 139.914 143.394 215.126 1.00 57.07  ? 452  MET B CA  1 
ATOM   10320 C  C   . MET B 1 452 ? 140.399 142.544 216.293 1.00 57.07  ? 452  MET B C   1 
ATOM   10321 O  O   . MET B 1 452 ? 141.183 142.995 217.129 1.00 57.07  ? 452  MET B O   1 
ATOM   10322 C  CB  . MET B 1 452 ? 140.923 143.343 213.976 1.00 57.07  ? 452  MET B CB  1 
ATOM   10323 C  CG  . MET B 1 452 ? 141.182 141.949 213.435 1.00 57.07  ? 452  MET B CG  1 
ATOM   10324 S  SD  . MET B 1 452 ? 142.503 141.910 212.213 1.00 57.07  ? 452  MET B SD  1 
ATOM   10325 C  CE  . MET B 1 452 ? 142.445 143.585 211.580 1.00 57.07  ? 452  MET B CE  1 
ATOM   10326 N  N   . SER B 1 453 ? 139.929 141.298 216.348 1.00 59.93  ? 453  SER B N   1 
ATOM   10327 C  CA  . SER B 1 453 ? 140.269 140.456 217.486 1.00 59.93  ? 453  SER B CA  1 
ATOM   10328 C  C   . SER B 1 453 ? 140.661 139.066 217.012 1.00 59.93  ? 453  SER B C   1 
ATOM   10329 O  O   . SER B 1 453 ? 140.152 138.570 216.006 1.00 59.93  ? 453  SER B O   1 
ATOM   10330 C  CB  . SER B 1 453 ? 139.105 140.362 218.479 1.00 59.93  ? 453  SER B CB  1 
ATOM   10331 O  OG  . SER B 1 453 ? 138.542 141.639 218.724 1.00 59.93  ? 453  SER B OG  1 
ATOM   10332 N  N   . VAL B 1 454 ? 141.570 138.442 217.755 1.00 59.63  ? 454  VAL B N   1 
ATOM   10333 C  CA  . VAL B 1 454 ? 141.957 137.054 217.532 1.00 59.63  ? 454  VAL B CA  1 
ATOM   10334 C  C   . VAL B 1 454 ? 142.008 136.360 218.885 1.00 59.63  ? 454  VAL B C   1 
ATOM   10335 O  O   . VAL B 1 454 ? 142.643 136.859 219.820 1.00 59.63  ? 454  VAL B O   1 
ATOM   10336 C  CB  . VAL B 1 454 ? 143.313 136.941 216.809 1.00 59.63  ? 454  VAL B CB  1 
ATOM   10337 C  CG1 . VAL B 1 454 ? 143.854 135.528 216.911 1.00 59.63  ? 454  VAL B CG1 1 
ATOM   10338 C  CG2 . VAL B 1 454 ? 143.175 137.353 215.352 1.00 59.63  ? 454  VAL B CG2 1 
ATOM   10339 N  N   . VAL B 1 455 ? 141.333 135.221 218.999 1.00 66.16  ? 455  VAL B N   1 
ATOM   10340 C  CA  . VAL B 1 455 ? 141.316 134.438 220.226 1.00 66.16  ? 455  VAL B CA  1 
ATOM   10341 C  C   . VAL B 1 455 ? 142.209 133.225 220.019 1.00 66.16  ? 455  VAL B C   1 
ATOM   10342 O  O   . VAL B 1 455 ? 141.911 132.359 219.185 1.00 66.16  ? 455  VAL B O   1 
ATOM   10343 C  CB  . VAL B 1 455 ? 139.890 134.013 220.605 1.00 66.16  ? 455  VAL B CB  1 
ATOM   10344 C  CG1 . VAL B 1 455 ? 139.897 133.311 221.951 1.00 66.16  ? 455  VAL B CG1 1 
ATOM   10345 C  CG2 . VAL B 1 455 ? 138.966 135.214 220.623 1.00 66.16  ? 455  VAL B CG2 1 
ATOM   10346 N  N   . VAL B 1 456 ? 143.298 133.169 220.782 1.00 70.15  ? 456  VAL B N   1 
ATOM   10347 C  CA  . VAL B 1 456 ? 144.270 132.089 220.720 1.00 70.15  ? 456  VAL B CA  1 
ATOM   10348 C  C   . VAL B 1 456 ? 144.293 131.393 222.075 1.00 70.15  ? 456  VAL B C   1 
ATOM   10349 O  O   . VAL B 1 456 ? 143.557 131.750 222.993 1.00 70.15  ? 456  VAL B O   1 
ATOM   10350 C  CB  . VAL B 1 456 ? 145.675 132.590 220.340 1.00 70.15  ? 456  VAL B CB  1 
ATOM   10351 C  CG1 . VAL B 1 456 ? 145.676 133.136 218.927 1.00 70.15  ? 456  VAL B CG1 1 
ATOM   10352 C  CG2 . VAL B 1 456 ? 146.137 133.651 221.322 1.00 70.15  ? 456  VAL B CG2 1 
ATOM   10353 N  N   . ALA B 1 457 ? 145.147 130.380 222.191 1.00 80.19  ? 457  ALA B N   1 
ATOM   10354 C  CA  . ALA B 1 457 ? 145.300 129.679 223.457 1.00 80.19  ? 457  ALA B CA  1 
ATOM   10355 C  C   . ALA B 1 457 ? 146.700 129.100 223.564 1.00 80.19  ? 457  ALA B C   1 
ATOM   10356 O  O   . ALA B 1 457 ? 147.255 128.603 222.581 1.00 80.19  ? 457  ALA B O   1 
ATOM   10357 C  CB  . ALA B 1 457 ? 144.266 128.561 223.612 1.00 80.19  ? 457  ALA B CB  1 
ATOM   10358 N  N   . GLU B 1 458 ? 147.262 129.172 224.768 1.00 86.99  ? 458  GLU B N   1 
ATOM   10359 C  CA  . GLU B 1 458 ? 148.522 128.516 225.081 1.00 86.99  ? 458  GLU B CA  1 
ATOM   10360 C  C   . GLU B 1 458 ? 148.330 127.096 225.591 1.00 86.99  ? 458  GLU B C   1 
ATOM   10361 O  O   . GLU B 1 458 ? 149.310 126.348 225.684 1.00 86.99  ? 458  GLU B O   1 
ATOM   10362 C  CB  . GLU B 1 458 ? 149.293 129.332 226.122 1.00 86.99  ? 458  GLU B CB  1 
ATOM   10363 C  CG  . GLU B 1 458 ? 148.594 129.431 227.467 1.00 86.99  ? 458  GLU B CG  1 
ATOM   10364 C  CD  . GLU B 1 458 ? 149.286 130.390 228.415 1.00 86.99  ? 458  GLU B CD  1 
ATOM   10365 O  OE1 . GLU B 1 458 ? 150.213 131.100 227.972 1.00 86.99  ? 458  GLU B OE1 1 
ATOM   10366 O  OE2 . GLU B 1 458 ? 148.903 130.433 229.603 1.00 86.99  ? 458  GLU B OE2 1 
ATOM   10367 N  N   . ASN B 1 459 ? 147.101 126.713 225.917 1.00 94.10  ? 459  ASN B N   1 
ATOM   10368 C  CA  . ASN B 1 459 ? 146.784 125.384 226.422 1.00 94.10  ? 459  ASN B CA  1 
ATOM   10369 C  C   . ASN B 1 459 ? 145.304 125.126 226.164 1.00 94.10  ? 459  ASN B C   1 
ATOM   10370 O  O   . ASN B 1 459 ? 144.649 125.865 225.421 1.00 94.10  ? 459  ASN B O   1 
ATOM   10371 C  CB  . ASN B 1 459 ? 147.149 125.263 227.906 1.00 94.10  ? 459  ASN B CB  1 
ATOM   10372 C  CG  . ASN B 1 459 ? 146.582 126.396 228.743 1.00 94.10  ? 459  ASN B CG  1 
ATOM   10373 O  OD1 . ASN B 1 459 ? 145.388 126.692 228.688 1.00 94.10  ? 459  ASN B OD1 1 
ATOM   10374 N  ND2 . ASN B 1 459 ? 147.441 127.037 229.526 1.00 94.10  ? 459  ASN B ND2 1 
ATOM   10375 N  N   . THR B 1 460 ? 144.772 124.072 226.779 1.00 100.01 ? 460  THR B N   1 
ATOM   10376 C  CA  . THR B 1 460 ? 143.362 123.729 226.663 1.00 100.01 ? 460  THR B CA  1 
ATOM   10377 C  C   . THR B 1 460 ? 142.540 124.216 227.849 1.00 100.01 ? 460  THR B C   1 
ATOM   10378 O  O   . THR B 1 460 ? 141.349 123.900 227.936 1.00 100.01 ? 460  THR B O   1 
ATOM   10379 C  CB  . THR B 1 460 ? 143.195 122.217 226.501 1.00 100.01 ? 460  THR B CB  1 
ATOM   10380 O  OG1 . THR B 1 460 ? 141.801 121.892 226.438 1.00 100.01 ? 460  THR B OG1 1 
ATOM   10381 C  CG2 . THR B 1 460 ? 143.831 121.482 227.671 1.00 100.01 ? 460  THR B CG2 1 
ATOM   10382 N  N   . GLU B 1 461 ? 143.144 124.974 228.763 1.00 96.48  ? 461  GLU B N   1 
ATOM   10383 C  CA  . GLU B 1 461 ? 142.463 125.451 229.961 1.00 96.48  ? 461  GLU B CA  1 
ATOM   10384 C  C   . GLU B 1 461 ? 141.845 126.832 229.779 1.00 96.48  ? 461  GLU B C   1 
ATOM   10385 O  O   . GLU B 1 461 ? 140.666 127.027 230.088 1.00 96.48  ? 461  GLU B O   1 
ATOM   10386 C  CB  . GLU B 1 461 ? 143.438 125.471 231.145 1.00 96.48  ? 461  GLU B CB  1 
ATOM   10387 C  CG  . GLU B 1 461 ? 143.966 124.101 231.533 1.00 96.48  ? 461  GLU B CG  1 
ATOM   10388 C  CD  . GLU B 1 461 ? 142.876 123.050 231.579 1.00 96.48  ? 461  GLU B CD  1 
ATOM   10389 O  OE1 . GLU B 1 461 ? 141.946 123.190 232.401 1.00 96.48  ? 461  GLU B OE1 1 
ATOM   10390 O  OE2 . GLU B 1 461 ? 142.949 122.082 230.793 1.00 96.48  ? 461  GLU B OE2 1 
ATOM   10391 N  N   . HIS B 1 462 ? 142.617 127.797 229.286 1.00 87.58  ? 462  HIS B N   1 
ATOM   10392 C  CA  . HIS B 1 462 ? 142.148 129.164 229.125 1.00 87.58  ? 462  HIS B CA  1 
ATOM   10393 C  C   . HIS B 1 462 ? 142.530 129.684 227.748 1.00 87.58  ? 462  HIS B C   1 
ATOM   10394 O  O   . HIS B 1 462 ? 143.506 129.234 227.143 1.00 87.58  ? 462  HIS B O   1 
ATOM   10395 C  CB  . HIS B 1 462 ? 142.728 130.088 230.204 1.00 87.58  ? 462  HIS B CB  1 
ATOM   10396 C  CG  . HIS B 1 462 ? 142.358 129.693 231.599 1.00 87.58  ? 462  HIS B CG  1 
ATOM   10397 N  ND1 . HIS B 1 462 ? 143.058 128.745 232.314 1.00 87.58  ? 462  HIS B ND1 1 
ATOM   10398 C  CD2 . HIS B 1 462 ? 141.361 130.116 232.411 1.00 87.58  ? 462  HIS B CD2 1 
ATOM   10399 C  CE1 . HIS B 1 462 ? 142.509 128.602 233.506 1.00 87.58  ? 462  HIS B CE1 1 
ATOM   10400 N  NE2 . HIS B 1 462 ? 141.477 129.422 233.591 1.00 87.58  ? 462  HIS B NE2 1 
ATOM   10401 N  N   . HIS B 1 463 ? 141.746 130.640 227.259 1.00 79.77  ? 463  HIS B N   1 
ATOM   10402 C  CA  . HIS B 1 463 ? 141.996 131.289 225.983 1.00 79.77  ? 463  HIS B CA  1 
ATOM   10403 C  C   . HIS B 1 463 ? 142.273 132.768 226.209 1.00 79.77  ? 463  HIS B C   1 
ATOM   10404 O  O   . HIS B 1 463 ? 141.771 133.375 227.160 1.00 79.77  ? 463  HIS B O   1 
ATOM   10405 C  CB  . HIS B 1 463 ? 140.812 131.121 225.023 1.00 79.77  ? 463  HIS B CB  1 
ATOM   10406 C  CG  . HIS B 1 463 ? 140.413 129.696 224.796 1.00 79.77  ? 463  HIS B CG  1 
ATOM   10407 N  ND1 . HIS B 1 463 ? 139.183 129.340 224.287 1.00 79.77  ? 463  HIS B ND1 1 
ATOM   10408 C  CD2 . HIS B 1 463 ? 141.081 128.537 225.008 1.00 79.77  ? 463  HIS B CD2 1 
ATOM   10409 C  CE1 . HIS B 1 463 ? 139.110 128.025 224.194 1.00 79.77  ? 463  HIS B CE1 1 
ATOM   10410 N  NE2 . HIS B 1 463 ? 140.249 127.513 224.626 1.00 79.77  ? 463  HIS B NE2 1 
ATOM   10411 N  N   . GLN B 1 464 ? 143.094 133.339 225.336 1.00 69.17  ? 464  GLN B N   1 
ATOM   10412 C  CA  . GLN B 1 464 ? 143.432 134.754 225.376 1.00 69.17  ? 464  GLN B CA  1 
ATOM   10413 C  C   . GLN B 1 464 ? 142.879 135.431 224.130 1.00 69.17  ? 464  GLN B C   1 
ATOM   10414 O  O   . GLN B 1 464 ? 143.207 135.037 223.005 1.00 69.17  ? 464  GLN B O   1 
ATOM   10415 C  CB  . GLN B 1 464 ? 144.944 134.957 225.474 1.00 69.17  ? 464  GLN B CB  1 
ATOM   10416 C  CG  . GLN B 1 464 ? 145.378 136.404 225.324 1.00 69.17  ? 464  GLN B CG  1 
ATOM   10417 C  CD  . GLN B 1 464 ? 146.767 136.657 225.873 1.00 69.17  ? 464  GLN B CD  1 
ATOM   10418 O  OE1 . GLN B 1 464 ? 147.363 135.789 226.509 1.00 69.17  ? 464  GLN B OE1 1 
ATOM   10419 N  NE2 . GLN B 1 464 ? 147.290 137.853 225.630 1.00 69.17  ? 464  GLN B NE2 1 
ATOM   10420 N  N   . LEU B 1 465 ? 142.039 136.438 224.335 1.00 60.63  ? 465  LEU B N   1 
ATOM   10421 C  CA  . LEU B 1 465 ? 141.532 137.282 223.263 1.00 60.63  ? 465  LEU B CA  1 
ATOM   10422 C  C   . LEU B 1 465 ? 142.421 138.514 223.169 1.00 60.63  ? 465  LEU B C   1 
ATOM   10423 O  O   . LEU B 1 465 ? 142.543 139.267 224.141 1.00 60.63  ? 465  LEU B O   1 
ATOM   10424 C  CB  . LEU B 1 465 ? 140.078 137.677 223.524 1.00 60.63  ? 465  LEU B CB  1 
ATOM   10425 C  CG  . LEU B 1 465 ? 139.407 138.674 222.575 1.00 60.63  ? 465  LEU B CG  1 
ATOM   10426 C  CD1 . LEU B 1 465 ? 137.980 138.250 222.276 1.00 60.63  ? 465  LEU B CD1 1 
ATOM   10427 C  CD2 . LEU B 1 465 ? 139.425 140.077 223.159 1.00 60.63  ? 465  LEU B CD2 1 
ATOM   10428 N  N   . VAL B 1 466 ? 143.047 138.711 222.012 1.00 55.30  ? 466  VAL B N   1 
ATOM   10429 C  CA  . VAL B 1 466 ? 143.906 139.860 221.759 1.00 55.30  ? 466  VAL B CA  1 
ATOM   10430 C  C   . VAL B 1 466 ? 143.243 140.676 220.661 1.00 55.30  ? 466  VAL B C   1 
ATOM   10431 O  O   . VAL B 1 466 ? 143.032 140.177 219.549 1.00 55.30  ? 466  VAL B O   1 
ATOM   10432 C  CB  . VAL B 1 466 ? 145.326 139.442 221.354 1.00 55.30  ? 466  VAL B CB  1 
ATOM   10433 C  CG1 . VAL B 1 466 ? 146.169 140.667 221.037 1.00 55.30  ? 466  VAL B CG1 1 
ATOM   10434 C  CG2 . VAL B 1 466 ? 145.968 138.608 222.450 1.00 55.30  ? 466  VAL B CG2 1 
ATOM   10435 N  N   . CYS B 1 467 ? 142.911 141.925 220.967 1.00 52.88  ? 467  CYS B N   1 
ATOM   10436 C  CA  . CYS B 1 467 ? 142.256 142.813 220.021 1.00 52.88  ? 467  CYS B CA  1 
ATOM   10437 C  C   . CYS B 1 467 ? 143.098 144.064 219.822 1.00 52.88  ? 467  CYS B C   1 
ATOM   10438 O  O   . CYS B 1 467 ? 143.862 144.459 220.708 1.00 52.88  ? 467  CYS B O   1 
ATOM   10439 C  CB  . CYS B 1 467 ? 140.854 143.196 220.501 1.00 52.88  ? 467  CYS B CB  1 
ATOM   10440 S  SG  . CYS B 1 467 ? 140.825 144.533 221.709 1.00 52.88  ? 467  CYS B SG  1 
ATOM   10441 N  N   . LYS B 1 468 ? 142.971 144.671 218.648 1.00 49.51  ? 468  LYS B N   1 
ATOM   10442 C  CA  . LYS B 1 468 ? 143.687 145.896 218.335 1.00 49.51  ? 468  LYS B CA  1 
ATOM   10443 C  C   . LYS B 1 468 ? 142.813 146.795 217.477 1.00 49.51  ? 468  LYS B C   1 
ATOM   10444 O  O   . LYS B 1 468 ? 141.930 146.319 216.752 1.00 49.51  ? 468  LYS B O   1 
ATOM   10445 C  CB  . LYS B 1 468 ? 145.018 145.600 217.627 1.00 49.51  ? 468  LYS B CB  1 
ATOM   10446 C  CG  . LYS B 1 468 ? 144.912 145.367 216.132 1.00 49.51  ? 468  LYS B CG  1 
ATOM   10447 C  CD  . LYS B 1 468 ? 146.249 144.925 215.557 1.00 49.51  ? 468  LYS B CD  1 
ATOM   10448 C  CE  . LYS B 1 468 ? 146.312 145.163 214.058 1.00 49.51  ? 468  LYS B CE  1 
ATOM   10449 N  NZ  . LYS B 1 468 ? 145.082 144.689 213.369 1.00 49.51  ? 468  LYS B NZ  1 
ATOM   10450 N  N   . GLY B 1 469 ? 143.061 148.097 217.568 1.00 46.61  ? 469  GLY B N   1 
ATOM   10451 C  CA  . GLY B 1 469 ? 142.291 149.035 216.772 1.00 46.61  ? 469  GLY B CA  1 
ATOM   10452 C  C   . GLY B 1 469 ? 142.590 150.464 217.162 1.00 46.61  ? 469  GLY B C   1 
ATOM   10453 O  O   . GLY B 1 469 ? 143.557 150.755 217.871 1.00 46.61  ? 469  GLY B O   1 
ATOM   10454 N  N   . ALA B 1 470 ? 141.741 151.366 216.671 1.00 51.75  ? 470  ALA B N   1 
ATOM   10455 C  CA  . ALA B 1 470 ? 141.889 152.778 216.993 1.00 51.75  ? 470  ALA B CA  1 
ATOM   10456 C  C   . ALA B 1 470 ? 141.780 152.990 218.498 1.00 51.75  ? 470  ALA B C   1 
ATOM   10457 O  O   . ALA B 1 470 ? 141.138 152.213 219.210 1.00 51.75  ? 470  ALA B O   1 
ATOM   10458 C  CB  . ALA B 1 470 ? 140.834 153.607 216.259 1.00 51.75  ? 470  ALA B CB  1 
ATOM   10459 N  N   . LEU B 1 471 ? 142.423 154.056 218.982 1.00 48.58  ? 471  LEU B N   1 
ATOM   10460 C  CA  . LEU B 1 471 ? 142.560 154.254 220.422 1.00 48.58  ? 471  LEU B CA  1 
ATOM   10461 C  C   . LEU B 1 471 ? 141.204 154.384 221.106 1.00 48.58  ? 471  LEU B C   1 
ATOM   10462 O  O   . LEU B 1 471 ? 140.952 153.741 222.132 1.00 48.58  ? 471  LEU B O   1 
ATOM   10463 C  CB  . LEU B 1 471 ? 143.407 155.492 220.705 1.00 48.58  ? 471  LEU B CB  1 
ATOM   10464 C  CG  . LEU B 1 471 ? 143.516 155.798 222.199 1.00 48.58  ? 471  LEU B CG  1 
ATOM   10465 C  CD1 . LEU B 1 471 ? 144.588 154.940 222.858 1.00 48.58  ? 471  LEU B CD1 1 
ATOM   10466 C  CD2 . LEU B 1 471 ? 143.753 157.272 222.445 1.00 48.58  ? 471  LEU B CD2 1 
ATOM   10467 N  N   . GLN B 1 472 ? 140.322 155.224 220.561 1.00 57.23  ? 472  GLN B N   1 
ATOM   10468 C  CA  . GLN B 1 472 ? 139.052 155.494 221.230 1.00 57.23  ? 472  GLN B CA  1 
ATOM   10469 C  C   . GLN B 1 472 ? 138.185 154.244 221.308 1.00 57.23  ? 472  GLN B C   1 
ATOM   10470 O  O   . GLN B 1 472 ? 137.562 153.977 222.342 1.00 57.23  ? 472  GLN B O   1 
ATOM   10471 C  CB  . GLN B 1 472 ? 138.310 156.619 220.512 1.00 57.23  ? 472  GLN B CB  1 
ATOM   10472 C  CG  . GLN B 1 472 ? 137.170 157.215 221.318 1.00 57.23  ? 472  GLN B CG  1 
ATOM   10473 C  CD  . GLN B 1 472 ? 137.619 157.716 222.676 1.00 57.23  ? 472  GLN B CD  1 
ATOM   10474 O  OE1 . GLN B 1 472 ? 137.245 157.163 223.710 1.00 57.23  ? 472  GLN B OE1 1 
ATOM   10475 N  NE2 . GLN B 1 472 ? 138.427 158.770 222.680 1.00 57.23  ? 472  GLN B NE2 1 
ATOM   10476 N  N   . GLU B 1 473 ? 138.134 153.466 220.226 1.00 59.01  ? 473  GLU B N   1 
ATOM   10477 C  CA  . GLU B 1 473 ? 137.314 152.259 220.219 1.00 59.01  ? 473  GLU B CA  1 
ATOM   10478 C  C   . GLU B 1 473 ? 137.835 151.227 221.212 1.00 59.01  ? 473  GLU B C   1 
ATOM   10479 O  O   . GLU B 1 473 ? 137.049 150.559 221.894 1.00 59.01  ? 473  GLU B O   1 
ATOM   10480 C  CB  . GLU B 1 473 ? 137.256 151.682 218.806 1.00 59.01  ? 473  GLU B CB  1 
ATOM   10481 C  CG  . GLU B 1 473 ? 136.361 152.472 217.856 1.00 59.01  ? 473  GLU B CG  1 
ATOM   10482 C  CD  . GLU B 1 473 ? 137.005 153.750 217.350 1.00 59.01  ? 473  GLU B CD  1 
ATOM   10483 O  OE1 . GLU B 1 473 ? 138.116 154.087 217.807 1.00 59.01  ? 473  GLU B OE1 1 
ATOM   10484 O  OE2 . GLU B 1 473 ? 136.395 154.424 216.494 1.00 59.01  ? 473  GLU B OE2 1 
ATOM   10485 N  N   . ILE B 1 474 ? 139.158 151.076 221.302 1.00 52.81  ? 474  ILE B N   1 
ATOM   10486 C  CA  . ILE B 1 474 ? 139.732 150.162 222.286 1.00 52.81  ? 474  ILE B CA  1 
ATOM   10487 C  C   . ILE B 1 474 ? 139.437 150.645 223.701 1.00 52.81  ? 474  ILE B C   1 
ATOM   10488 O  O   . ILE B 1 474 ? 139.070 149.853 224.577 1.00 52.81  ? 474  ILE B O   1 
ATOM   10489 C  CB  . ILE B 1 474 ? 141.243 149.998 222.047 1.00 52.81  ? 474  ILE B CB  1 
ATOM   10490 C  CG1 . ILE B 1 474 ? 141.505 149.406 220.662 1.00 52.81  ? 474  ILE B CG1 1 
ATOM   10491 C  CG2 . ILE B 1 474 ? 141.858 149.122 223.122 1.00 52.81  ? 474  ILE B CG2 1 
ATOM   10492 C  CD1 . ILE B 1 474 ? 141.151 147.945 220.546 1.00 52.81  ? 474  ILE B CD1 1 
ATOM   10493 N  N   . LEU B 1 475 ? 139.588 151.948 223.947 1.00 55.11  ? 475  LEU B N   1 
ATOM   10494 C  CA  . LEU B 1 475 ? 139.345 152.486 225.281 1.00 55.11  ? 475  LEU B CA  1 
ATOM   10495 C  C   . LEU B 1 475 ? 137.879 152.374 225.678 1.00 55.11  ? 475  LEU B C   1 
ATOM   10496 O  O   . LEU B 1 475 ? 137.568 152.286 226.871 1.00 55.11  ? 475  LEU B O   1 
ATOM   10497 C  CB  . LEU B 1 475 ? 139.802 153.942 225.350 1.00 55.11  ? 475  LEU B CB  1 
ATOM   10498 C  CG  . LEU B 1 475 ? 141.310 154.170 225.451 1.00 55.11  ? 475  LEU B CG  1 
ATOM   10499 C  CD1 . LEU B 1 475 ? 141.624 155.653 225.548 1.00 55.11  ? 475  LEU B CD1 1 
ATOM   10500 C  CD2 . LEU B 1 475 ? 141.886 153.418 226.639 1.00 55.11  ? 475  LEU B CD2 1 
ATOM   10501 N  N   . ASN B 1 476 ? 136.970 152.385 224.701 1.00 58.01  ? 476  ASN B N   1 
ATOM   10502 C  CA  . ASN B 1 476 ? 135.552 152.237 225.012 1.00 58.01  ? 476  ASN B CA  1 
ATOM   10503 C  C   . ASN B 1 476 ? 135.258 150.877 225.633 1.00 58.01  ? 476  ASN B C   1 
ATOM   10504 O  O   . ASN B 1 476 ? 134.341 150.745 226.452 1.00 58.01  ? 476  ASN B O   1 
ATOM   10505 C  CB  . ASN B 1 476 ? 134.713 152.439 223.751 1.00 58.01  ? 476  ASN B CB  1 
ATOM   10506 C  CG  . ASN B 1 476 ? 134.677 153.884 223.302 1.00 58.01  ? 476  ASN B CG  1 
ATOM   10507 O  OD1 . ASN B 1 476 ? 135.156 154.776 224.002 1.00 58.01  ? 476  ASN B OD1 1 
ATOM   10508 N  ND2 . ASN B 1 476 ? 134.110 154.124 222.126 1.00 58.01  ? 476  ASN B ND2 1 
ATOM   10509 N  N   . VAL B 1 477 ? 136.023 149.852 225.256 1.00 58.64  ? 477  VAL B N   1 
ATOM   10510 C  CA  . VAL B 1 477 ? 135.796 148.496 225.740 1.00 58.64  ? 477  VAL B CA  1 
ATOM   10511 C  C   . VAL B 1 477 ? 136.899 148.030 226.686 1.00 58.64  ? 477  VAL B C   1 
ATOM   10512 O  O   . VAL B 1 477 ? 137.073 146.823 226.878 1.00 58.64  ? 477  VAL B O   1 
ATOM   10513 C  CB  . VAL B 1 477 ? 135.634 147.515 224.569 1.00 58.64  ? 477  VAL B CB  1 
ATOM   10514 C  CG1 . VAL B 1 477 ? 134.318 147.764 223.851 1.00 58.64  ? 477  VAL B CG1 1 
ATOM   10515 C  CG2 . VAL B 1 477 ? 136.801 147.645 223.608 1.00 58.64  ? 477  VAL B CG2 1 
ATOM   10516 N  N   . CYS B 1 478 ? 137.648 148.954 227.279 1.00 60.74  ? 478  CYS B N   1 
ATOM   10517 C  CA  . CYS B 1 478 ? 138.703 148.616 228.226 1.00 60.74  ? 478  CYS B CA  1 
ATOM   10518 C  C   . CYS B 1 478 ? 138.334 149.115 229.616 1.00 60.74  ? 478  CYS B C   1 
ATOM   10519 O  O   . CYS B 1 478 ? 137.950 150.277 229.783 1.00 60.74  ? 478  CYS B O   1 
ATOM   10520 C  CB  . CYS B 1 478 ? 140.043 149.210 227.792 1.00 60.74  ? 478  CYS B CB  1 
ATOM   10521 S  SG  . CYS B 1 478 ? 140.928 148.226 226.566 1.00 60.74  ? 478  CYS B SG  1 
ATOM   10522 N  N   . SER B 1 479 ? 138.454 148.232 230.610 1.00 64.96  ? 479  SER B N   1 
ATOM   10523 C  CA  . SER B 1 479 ? 138.200 148.582 231.999 1.00 64.96  ? 479  SER B CA  1 
ATOM   10524 C  C   . SER B 1 479 ? 139.432 148.488 232.886 1.00 64.96  ? 479  SER B C   1 
ATOM   10525 O  O   . SER B 1 479 ? 139.459 149.121 233.945 1.00 64.96  ? 479  SER B O   1 
ATOM   10526 C  CB  . SER B 1 479 ? 137.100 147.683 232.584 1.00 64.96  ? 479  SER B CB  1 
ATOM   10527 O  OG  . SER B 1 479 ? 136.568 148.236 233.775 1.00 64.96  ? 479  SER B OG  1 
ATOM   10528 N  N   . GLN B 1 480 ? 140.443 147.722 232.484 1.00 65.49  ? 480  GLN B N   1 
ATOM   10529 C  CA  . GLN B 1 480 ? 141.668 147.559 233.250 1.00 65.49  ? 480  GLN B CA  1 
ATOM   10530 C  C   . GLN B 1 480 ? 142.862 147.875 232.361 1.00 65.49  ? 480  GLN B C   1 
ATOM   10531 O  O   . GLN B 1 480 ? 142.795 147.764 231.135 1.00 65.49  ? 480  GLN B O   1 
ATOM   10532 C  CB  . GLN B 1 480 ? 141.796 146.138 233.812 1.00 65.49  ? 480  GLN B CB  1 
ATOM   10533 C  CG  . GLN B 1 480 ? 140.649 145.713 234.711 1.00 65.49  ? 480  GLN B CG  1 
ATOM   10534 C  CD  . GLN B 1 480 ? 140.827 144.307 235.247 1.00 65.49  ? 480  GLN B CD  1 
ATOM   10535 O  OE1 . GLN B 1 480 ? 140.917 143.346 234.483 1.00 65.49  ? 480  GLN B OE1 1 
ATOM   10536 N  NE2 . GLN B 1 480 ? 140.886 144.180 236.567 1.00 65.49  ? 480  GLN B NE2 1 
ATOM   10537 N  N   . VAL B 1 481 ? 143.961 148.276 232.993 1.00 61.00  ? 481  VAL B N   1 
ATOM   10538 C  CA  . VAL B 1 481 ? 145.195 148.589 232.282 1.00 61.00  ? 481  VAL B CA  1 
ATOM   10539 C  C   . VAL B 1 481 ? 146.367 147.999 233.055 1.00 61.00  ? 481  VAL B C   1 
ATOM   10540 O  O   . VAL B 1 481 ? 146.383 148.009 234.291 1.00 61.00  ? 481  VAL B O   1 
ATOM   10541 C  CB  . VAL B 1 481 ? 145.361 150.110 232.071 1.00 61.00  ? 481  VAL B CB  1 
ATOM   10542 C  CG1 . VAL B 1 481 ? 145.457 150.839 233.399 1.00 61.00  ? 481  VAL B CG1 1 
ATOM   10543 C  CG2 . VAL B 1 481 ? 146.578 150.401 231.209 1.00 61.00  ? 481  VAL B CG2 1 
ATOM   10544 N  N   . ARG B 1 482 ? 147.339 147.462 232.322 1.00 59.38  ? 482  ARG B N   1 
ATOM   10545 C  CA  . ARG B 1 482 ? 148.530 146.865 232.920 1.00 59.38  ? 482  ARG B CA  1 
ATOM   10546 C  C   . ARG B 1 482 ? 149.574 147.962 233.084 1.00 59.38  ? 482  ARG B C   1 
ATOM   10547 O  O   . ARG B 1 482 ? 150.346 148.246 232.165 1.00 59.38  ? 482  ARG B O   1 
ATOM   10548 C  CB  . ARG B 1 482 ? 149.046 145.717 232.060 1.00 59.38  ? 482  ARG B CB  1 
ATOM   10549 C  CG  . ARG B 1 482 ? 150.038 144.812 232.763 1.00 59.38  ? 482  ARG B CG  1 
ATOM   10550 C  CD  . ARG B 1 482 ? 150.622 143.794 231.801 1.00 59.38  ? 482  ARG B CD  1 
ATOM   10551 N  NE  . ARG B 1 482 ? 149.623 142.831 231.354 1.00 59.38  ? 482  ARG B NE  1 
ATOM   10552 C  CZ  . ARG B 1 482 ? 149.289 141.734 232.020 1.00 59.38  ? 482  ARG B CZ  1 
ATOM   10553 N  NH1 . ARG B 1 482 ? 149.856 141.428 233.176 1.00 59.38  ? 482  ARG B NH1 1 
ATOM   10554 N  NH2 . ARG B 1 482 ? 148.366 140.923 231.513 1.00 59.38  ? 482  ARG B NH2 1 
ATOM   10555 N  N   . HIS B 1 483 ? 149.598 148.581 234.261 1.00 65.53  ? 483  HIS B N   1 
ATOM   10556 C  CA  . HIS B 1 483 ? 150.505 149.680 234.563 1.00 65.53  ? 483  HIS B CA  1 
ATOM   10557 C  C   . HIS B 1 483 ? 151.537 149.199 235.571 1.00 65.53  ? 483  HIS B C   1 
ATOM   10558 O  O   . HIS B 1 483 ? 151.176 148.640 236.613 1.00 65.53  ? 483  HIS B O   1 
ATOM   10559 C  CB  . HIS B 1 483 ? 149.738 150.887 235.107 1.00 65.53  ? 483  HIS B CB  1 
ATOM   10560 C  CG  . HIS B 1 483 ? 150.553 152.140 235.179 1.00 65.53  ? 483  HIS B CG  1 
ATOM   10561 N  ND1 . HIS B 1 483 ? 150.151 153.249 235.892 1.00 65.53  ? 483  HIS B ND1 1 
ATOM   10562 C  CD2 . HIS B 1 483 ? 151.748 152.459 234.629 1.00 65.53  ? 483  HIS B CD2 1 
ATOM   10563 C  CE1 . HIS B 1 483 ? 151.063 154.198 235.777 1.00 65.53  ? 483  HIS B CE1 1 
ATOM   10564 N  NE2 . HIS B 1 483 ? 152.042 153.744 235.015 1.00 65.53  ? 483  HIS B NE2 1 
ATOM   10565 N  N   . ASN B 1 484 ? 152.816 149.402 235.249 1.00 69.53  ? 484  ASN B N   1 
ATOM   10566 C  CA  . ASN B 1 484 ? 153.930 149.029 236.122 1.00 69.53  ? 484  ASN B CA  1 
ATOM   10567 C  C   . ASN B 1 484 ? 153.897 147.546 236.484 1.00 69.53  ? 484  ASN B C   1 
ATOM   10568 O  O   . ASN B 1 484 ? 154.322 147.152 237.572 1.00 69.53  ? 484  ASN B O   1 
ATOM   10569 C  CB  . ASN B 1 484 ? 153.954 149.888 237.389 1.00 69.53  ? 484  ASN B CB  1 
ATOM   10570 C  CG  . ASN B 1 484 ? 153.913 151.372 237.086 1.00 69.53  ? 484  ASN B CG  1 
ATOM   10571 O  OD1 . ASN B 1 484 ? 154.572 151.845 236.160 1.00 69.53  ? 484  ASN B OD1 1 
ATOM   10572 N  ND2 . ASN B 1 484 ? 153.137 152.114 237.866 1.00 69.53  ? 484  ASN B ND2 1 
ATOM   10573 N  N   . GLY B 1 485 ? 153.391 146.714 235.576 1.00 71.24  ? 485  GLY B N   1 
ATOM   10574 C  CA  . GLY B 1 485 ? 153.301 145.290 235.808 1.00 71.24  ? 485  GLY B CA  1 
ATOM   10575 C  C   . GLY B 1 485 ? 152.110 144.842 236.626 1.00 71.24  ? 485  GLY B C   1 
ATOM   10576 O  O   . GLY B 1 485 ? 151.998 143.644 236.918 1.00 71.24  ? 485  GLY B O   1 
ATOM   10577 N  N   . GLU B 1 486 ? 151.220 145.754 237.007 1.00 72.64  ? 486  GLU B N   1 
ATOM   10578 C  CA  . GLU B 1 486 ? 150.051 145.423 237.809 1.00 72.64  ? 486  GLU B CA  1 
ATOM   10579 C  C   . GLU B 1 486 ? 148.779 145.815 237.070 1.00 72.64  ? 486  GLU B C   1 
ATOM   10580 O  O   . GLU B 1 486 ? 148.726 146.859 236.412 1.00 72.64  ? 486  GLU B O   1 
ATOM   10581 C  CB  . GLU B 1 486 ? 150.099 146.123 239.169 1.00 72.64  ? 486  GLU B CB  1 
ATOM   10582 C  CG  . GLU B 1 486 ? 151.302 145.748 240.017 1.00 72.64  ? 486  GLU B CG  1 
ATOM   10583 C  CD  . GLU B 1 486 ? 151.358 146.520 241.319 1.00 72.64  ? 486  GLU B CD  1 
ATOM   10584 O  OE1 . GLU B 1 486 ? 150.781 147.626 241.381 1.00 72.64  ? 486  GLU B OE1 1 
ATOM   10585 O  OE2 . GLU B 1 486 ? 151.978 146.022 242.282 1.00 72.64  ? 486  GLU B OE2 1 
ATOM   10586 N  N   . ILE B 1 487 ? 147.756 144.972 237.181 1.00 65.51  ? 487  ILE B N   1 
ATOM   10587 C  CA  . ILE B 1 487 ? 146.465 145.231 236.553 1.00 65.51  ? 487  ILE B CA  1 
ATOM   10588 C  C   . ILE B 1 487 ? 145.685 146.185 237.453 1.00 65.51  ? 487  ILE B C   1 
ATOM   10589 O  O   . ILE B 1 487 ? 145.224 145.799 238.529 1.00 65.51  ? 487  ILE B O   1 
ATOM   10590 C  CB  . ILE B 1 487 ? 145.687 143.933 236.314 1.00 65.51  ? 487  ILE B CB  1 
ATOM   10591 C  CG1 . ILE B 1 487 ? 146.552 142.924 235.558 1.00 65.51  ? 487  ILE B CG1 1 
ATOM   10592 C  CG2 . ILE B 1 487 ? 144.405 144.215 235.551 1.00 65.51  ? 487  ILE B CG2 1 
ATOM   10593 C  CD1 . ILE B 1 487 ? 146.927 143.368 234.164 1.00 65.51  ? 487  ILE B CD1 1 
ATOM   10594 N  N   . VAL B 1 488 ? 145.533 147.431 237.013 1.00 66.80  ? 488  VAL B N   1 
ATOM   10595 C  CA  . VAL B 1 488 ? 144.841 148.447 237.802 1.00 66.80  ? 488  VAL B CA  1 
ATOM   10596 C  C   . VAL B 1 488 ? 143.613 148.916 237.027 1.00 66.80  ? 488  VAL B C   1 
ATOM   10597 O  O   . VAL B 1 488 ? 143.655 148.998 235.790 1.00 66.80  ? 488  VAL B O   1 
ATOM   10598 C  CB  . VAL B 1 488 ? 145.789 149.610 238.151 1.00 66.80  ? 488  VAL B CB  1 
ATOM   10599 C  CG1 . VAL B 1 488 ? 146.205 150.370 236.902 1.00 66.80  ? 488  VAL B CG1 1 
ATOM   10600 C  CG2 . VAL B 1 488 ? 145.159 150.550 239.169 1.00 66.80  ? 488  VAL B CG2 1 
ATOM   10601 N  N   . PRO B 1 489 ? 142.494 149.195 237.698 1.00 67.53  ? 489  PRO B N   1 
ATOM   10602 C  CA  . PRO B 1 489 ? 141.326 149.727 236.986 1.00 67.53  ? 489  PRO B CA  1 
ATOM   10603 C  C   . PRO B 1 489 ? 141.649 151.035 236.280 1.00 67.53  ? 489  PRO B C   1 
ATOM   10604 O  O   . PRO B 1 489 ? 142.394 151.874 236.790 1.00 67.53  ? 489  PRO B O   1 
ATOM   10605 C  CB  . PRO B 1 489 ? 140.297 149.927 238.102 1.00 67.53  ? 489  PRO B CB  1 
ATOM   10606 C  CG  . PRO B 1 489 ? 140.656 148.897 239.112 1.00 67.53  ? 489  PRO B CG  1 
ATOM   10607 C  CD  . PRO B 1 489 ? 142.158 148.783 239.073 1.00 67.53  ? 489  PRO B CD  1 
ATOM   10608 N  N   . LEU B 1 490 ? 141.074 151.201 235.090 1.00 68.55  ? 490  LEU B N   1 
ATOM   10609 C  CA  . LEU B 1 490 ? 141.342 152.359 234.238 1.00 68.55  ? 490  LEU B CA  1 
ATOM   10610 C  C   . LEU B 1 490 ? 140.359 153.464 234.605 1.00 68.55  ? 490  LEU B C   1 
ATOM   10611 O  O   . LEU B 1 490 ? 139.200 153.461 234.189 1.00 68.55  ? 490  LEU B O   1 
ATOM   10612 C  CB  . LEU B 1 490 ? 141.238 151.973 232.768 1.00 68.55  ? 490  LEU B CB  1 
ATOM   10613 C  CG  . LEU B 1 490 ? 141.608 153.032 231.731 1.00 68.55  ? 490  LEU B CG  1 
ATOM   10614 C  CD1 . LEU B 1 490 ? 143.073 153.416 231.858 1.00 68.55  ? 490  LEU B CD1 1 
ATOM   10615 C  CD2 . LEU B 1 490 ? 141.308 152.521 230.332 1.00 68.55  ? 490  LEU B CD2 1 
ATOM   10616 N  N   . ASP B 1 491 ? 140.831 154.424 235.396 1.00 74.56  ? 491  ASP B N   1 
ATOM   10617 C  CA  . ASP B 1 491 ? 139.995 155.527 235.843 1.00 74.56  ? 491  ASP B CA  1 
ATOM   10618 C  C   . ASP B 1 491 ? 140.010 156.661 234.818 1.00 74.56  ? 491  ASP B C   1 
ATOM   10619 O  O   . ASP B 1 491 ? 140.608 156.563 233.743 1.00 74.56  ? 491  ASP B O   1 
ATOM   10620 C  CB  . ASP B 1 491 ? 140.451 156.016 237.215 1.00 74.56  ? 491  ASP B CB  1 
ATOM   10621 C  CG  . ASP B 1 491 ? 141.947 156.236 237.286 1.00 74.56  ? 491  ASP B CG  1 
ATOM   10622 O  OD1 . ASP B 1 491 ? 142.643 155.907 236.304 1.00 74.56  ? 491  ASP B OD1 1 
ATOM   10623 O  OD2 . ASP B 1 491 ? 142.427 156.739 238.324 1.00 74.56  ? 491  ASP B OD2 1 
ATOM   10624 N  N   . ASP B 1 492 ? 139.336 157.762 235.164 1.00 72.06  ? 492  ASP B N   1 
ATOM   10625 C  CA  . ASP B 1 492 ? 139.211 158.884 234.239 1.00 72.06  ? 492  ASP B CA  1 
ATOM   10626 C  C   . ASP B 1 492 ? 140.525 159.636 234.065 1.00 72.06  ? 492  ASP B C   1 
ATOM   10627 O  O   . ASP B 1 492 ? 140.797 160.155 232.976 1.00 72.06  ? 492  ASP B O   1 
ATOM   10628 C  CB  . ASP B 1 492 ? 138.118 159.838 234.722 1.00 72.06  ? 492  ASP B CB  1 
ATOM   10629 C  CG  . ASP B 1 492 ? 137.362 160.482 233.578 1.00 72.06  ? 492  ASP B CG  1 
ATOM   10630 O  OD1 . ASP B 1 492 ? 137.972 160.711 232.513 1.00 72.06  ? 492  ASP B OD1 1 
ATOM   10631 O  OD2 . ASP B 1 492 ? 136.155 160.760 233.745 1.00 72.06  ? 492  ASP B OD2 1 
ATOM   10632 N  N   . ILE B 1 493 ? 141.339 159.721 235.119 1.00 70.73  ? 493  ILE B N   1 
ATOM   10633 C  CA  . ILE B 1 493 ? 142.597 160.460 235.031 1.00 70.73  ? 493  ILE B CA  1 
ATOM   10634 C  C   . ILE B 1 493 ? 143.527 159.808 234.015 1.00 70.73  ? 493  ILE B C   1 
ATOM   10635 O  O   . ILE B 1 493 ? 144.121 160.483 233.164 1.00 70.73  ? 493  ILE B O   1 
ATOM   10636 C  CB  . ILE B 1 493 ? 143.259 160.560 236.417 1.00 70.73  ? 493  ILE B CB  1 
ATOM   10637 C  CG1 . ILE B 1 493 ? 142.234 160.985 237.470 1.00 70.73  ? 493  ILE B CG1 1 
ATOM   10638 C  CG2 . ILE B 1 493 ? 144.429 161.531 236.379 1.00 70.73  ? 493  ILE B CG2 1 
ATOM   10639 C  CD1 . ILE B 1 493 ? 141.672 162.372 237.251 1.00 70.73  ? 493  ILE B CD1 1 
ATOM   10640 N  N   . MET B 1 494 ? 143.665 158.482 234.090 1.00 70.40  ? 494  MET B N   1 
ATOM   10641 C  CA  . MET B 1 494 ? 144.484 157.772 233.115 1.00 70.40  ? 494  MET B CA  1 
ATOM   10642 C  C   . MET B 1 494 ? 143.909 157.892 231.712 1.00 70.40  ? 494  MET B C   1 
ATOM   10643 O  O   . MET B 1 494 ? 144.665 158.002 230.742 1.00 70.40  ? 494  MET B O   1 
ATOM   10644 C  CB  . MET B 1 494 ? 144.626 156.302 233.510 1.00 70.40  ? 494  MET B CB  1 
ATOM   10645 C  CG  . MET B 1 494 ? 145.444 156.075 234.770 1.00 70.40  ? 494  MET B CG  1 
ATOM   10646 S  SD  . MET B 1 494 ? 146.050 154.382 234.904 1.00 70.40  ? 494  MET B SD  1 
ATOM   10647 C  CE  . MET B 1 494 ? 146.556 154.335 236.621 1.00 70.40  ? 494  MET B CE  1 
ATOM   10648 N  N   . LEU B 1 495 ? 142.580 157.875 231.583 1.00 65.63  ? 495  LEU B N   1 
ATOM   10649 C  CA  . LEU B 1 495 ? 141.962 158.051 230.273 1.00 65.63  ? 495  LEU B CA  1 
ATOM   10650 C  C   . LEU B 1 495 ? 142.313 159.407 229.673 1.00 65.63  ? 495  LEU B C   1 
ATOM   10651 O  O   . LEU B 1 495 ? 142.674 159.495 228.495 1.00 65.63  ? 495  LEU B O   1 
ATOM   10652 C  CB  . LEU B 1 495 ? 140.447 157.890 230.381 1.00 65.63  ? 495  LEU B CB  1 
ATOM   10653 C  CG  . LEU B 1 495 ? 139.907 156.460 230.388 1.00 65.63  ? 495  LEU B CG  1 
ATOM   10654 C  CD1 . LEU B 1 495 ? 138.404 156.457 230.604 1.00 65.63  ? 495  LEU B CD1 1 
ATOM   10655 C  CD2 . LEU B 1 495 ? 140.259 155.764 229.088 1.00 65.63  ? 495  LEU B CD2 1 
ATOM   10656 N  N   . ARG B 1 496 ? 142.228 160.473 230.472 1.00 64.18  ? 496  ARG B N   1 
ATOM   10657 C  CA  . ARG B 1 496 ? 142.545 161.803 229.960 1.00 64.18  ? 496  ARG B CA  1 
ATOM   10658 C  C   . ARG B 1 496 ? 144.030 161.937 229.641 1.00 64.18  ? 496  ARG B C   1 
ATOM   10659 O  O   . ARG B 1 496 ? 144.401 162.574 228.647 1.00 64.18  ? 496  ARG B O   1 
ATOM   10660 C  CB  . ARG B 1 496 ? 142.106 162.870 230.962 1.00 64.18  ? 496  ARG B CB  1 
ATOM   10661 C  CG  . ARG B 1 496 ? 140.602 162.926 231.176 1.00 64.18  ? 496  ARG B CG  1 
ATOM   10662 C  CD  . ARG B 1 496 ? 140.204 164.101 232.056 1.00 64.18  ? 496  ARG B CD  1 
ATOM   10663 N  NE  . ARG B 1 496 ? 140.877 164.074 233.350 1.00 64.18  ? 496  ARG B NE  1 
ATOM   10664 C  CZ  . ARG B 1 496 ? 141.671 165.035 233.801 1.00 64.18  ? 496  ARG B CZ  1 
ATOM   10665 N  NH1 . ARG B 1 496 ? 141.918 166.121 233.086 1.00 64.18  ? 496  ARG B NH1 1 
ATOM   10666 N  NH2 . ARG B 1 496 ? 142.231 164.905 235.000 1.00 64.18  ? 496  ARG B NH2 1 
ATOM   10667 N  N   . LYS B 1 497 ? 144.894 161.350 230.472 1.00 60.13  ? 497  LYS B N   1 
ATOM   10668 C  CA  . LYS B 1 497 ? 146.327 161.389 230.192 1.00 60.13  ? 497  LYS B CA  1 
ATOM   10669 C  C   . LYS B 1 497 ? 146.648 160.661 228.891 1.00 60.13  ? 497  LYS B C   1 
ATOM   10670 O  O   . LYS B 1 497 ? 147.423 161.154 228.060 1.00 60.13  ? 497  LYS B O   1 
ATOM   10671 C  CB  . LYS B 1 497 ? 147.101 160.783 231.363 1.00 60.13  ? 497  LYS B CB  1 
ATOM   10672 C  CG  . LYS B 1 497 ? 148.540 160.418 231.045 1.00 60.13  ? 497  LYS B CG  1 
ATOM   10673 C  CD  . LYS B 1 497 ? 149.181 159.674 232.205 1.00 60.13  ? 497  LYS B CD  1 
ATOM   10674 C  CE  . LYS B 1 497 ? 150.602 159.251 231.874 1.00 60.13  ? 497  LYS B CE  1 
ATOM   10675 N  NZ  . LYS B 1 497 ? 151.246 158.531 233.007 1.00 60.13  ? 497  LYS B NZ  1 
ATOM   10676 N  N   . ILE B 1 498 ? 146.046 159.486 228.691 1.00 57.04  ? 498  ILE B N   1 
ATOM   10677 C  CA  . ILE B 1 498 ? 146.244 158.741 227.452 1.00 57.04  ? 498  ILE B CA  1 
ATOM   10678 C  C   . ILE B 1 498 ? 145.742 159.553 226.268 1.00 57.04  ? 498  ILE B C   1 
ATOM   10679 O  O   . ILE B 1 498 ? 146.390 159.620 225.216 1.00 57.04  ? 498  ILE B O   1 
ATOM   10680 C  CB  . ILE B 1 498 ? 145.545 157.372 227.536 1.00 57.04  ? 498  ILE B CB  1 
ATOM   10681 C  CG1 . ILE B 1 498 ? 146.343 156.418 228.424 1.00 57.04  ? 498  ILE B CG1 1 
ATOM   10682 C  CG2 . ILE B 1 498 ? 145.357 156.777 226.152 1.00 57.04  ? 498  ILE B CG2 1 
ATOM   10683 C  CD1 . ILE B 1 498 ? 145.610 155.135 228.739 1.00 57.04  ? 498  ILE B CD1 1 
ATOM   10684 N  N   . LYS B 1 499 ? 144.578 160.187 226.425 1.00 60.03  ? 499  LYS B N   1 
ATOM   10685 C  CA  . LYS B 1 499 ? 144.019 160.988 225.344 1.00 60.03  ? 499  LYS B CA  1 
ATOM   10686 C  C   . LYS B 1 499 ? 144.948 162.133 224.965 1.00 60.03  ? 499  LYS B C   1 
ATOM   10687 O  O   . LYS B 1 499 ? 145.181 162.379 223.779 1.00 60.03  ? 499  LYS B O   1 
ATOM   10688 C  CB  . LYS B 1 499 ? 142.645 161.524 225.742 1.00 60.03  ? 499  LYS B CB  1 
ATOM   10689 C  CG  . LYS B 1 499 ? 142.012 162.432 224.702 1.00 60.03  ? 499  LYS B CG  1 
ATOM   10690 C  CD  . LYS B 1 499 ? 140.740 163.071 225.231 1.00 60.03  ? 499  LYS B CD  1 
ATOM   10691 C  CE  . LYS B 1 499 ? 140.168 164.068 224.235 1.00 60.03  ? 499  LYS B CE  1 
ATOM   10692 N  NZ  . LYS B 1 499 ? 141.140 165.148 223.912 1.00 60.03  ? 499  LYS B NZ  1 
ATOM   10693 N  N   . ARG B 1 500 ? 145.502 162.837 225.956 1.00 57.50  ? 500  ARG B N   1 
ATOM   10694 C  CA  . ARG B 1 500 ? 146.364 163.975 225.640 1.00 57.50  ? 500  ARG B CA  1 
ATOM   10695 C  C   . ARG B 1 500 ? 147.680 163.515 225.015 1.00 57.50  ? 500  ARG B C   1 
ATOM   10696 O  O   . ARG B 1 500 ? 148.184 164.142 224.073 1.00 57.50  ? 500  ARG B O   1 
ATOM   10697 C  CB  . ARG B 1 500 ? 146.609 164.830 226.888 1.00 57.50  ? 500  ARG B CB  1 
ATOM   10698 C  CG  . ARG B 1 500 ? 147.538 164.234 227.929 1.00 57.50  ? 500  ARG B CG  1 
ATOM   10699 C  CD  . ARG B 1 500 ? 147.671 165.142 229.139 1.00 57.50  ? 500  ARG B CD  1 
ATOM   10700 N  NE  . ARG B 1 500 ? 148.591 164.596 230.129 1.00 57.50  ? 500  ARG B NE  1 
ATOM   10701 C  CZ  . ARG B 1 500 ? 148.864 165.168 231.294 1.00 57.50  ? 500  ARG B CZ  1 
ATOM   10702 N  NH1 . ARG B 1 500 ? 148.301 166.311 231.651 1.00 57.50  ? 500  ARG B NH1 1 
ATOM   10703 N  NH2 . ARG B 1 500 ? 149.722 164.578 232.121 1.00 57.50  ? 500  ARG B NH2 1 
ATOM   10704 N  N   . VAL B 1 501 ? 148.245 162.409 225.509 1.00 49.53  ? 501  VAL B N   1 
ATOM   10705 C  CA  . VAL B 1 501 ? 149.491 161.904 224.933 1.00 49.53  ? 501  VAL B CA  1 
ATOM   10706 C  C   . VAL B 1 501 ? 149.274 161.480 223.486 1.00 49.53  ? 501  VAL B C   1 
ATOM   10707 O  O   . VAL B 1 501 ? 150.075 161.798 222.596 1.00 49.53  ? 501  VAL B O   1 
ATOM   10708 C  CB  . VAL B 1 501 ? 150.054 160.751 225.782 1.00 49.53  ? 501  VAL B CB  1 
ATOM   10709 C  CG1 . VAL B 1 501 ? 151.256 160.130 225.095 1.00 49.53  ? 501  VAL B CG1 1 
ATOM   10710 C  CG2 . VAL B 1 501 ? 150.445 161.256 227.158 1.00 49.53  ? 501  VAL B CG2 1 
ATOM   10711 N  N   . THR B 1 502 ? 148.180 160.763 223.225 1.00 49.22  ? 502  THR B N   1 
ATOM   10712 C  CA  . THR B 1 502 ? 147.906 160.319 221.864 1.00 49.22  ? 502  THR B CA  1 
ATOM   10713 C  C   . THR B 1 502 ? 147.548 161.490 220.959 1.00 49.22  ? 502  THR B C   1 
ATOM   10714 O  O   . THR B 1 502 ? 147.836 161.461 219.760 1.00 49.22  ? 502  THR B O   1 
ATOM   10715 C  CB  . THR B 1 502 ? 146.790 159.279 221.866 1.00 49.22  ? 502  THR B CB  1 
ATOM   10716 O  OG1 . THR B 1 502 ? 145.650 159.809 222.551 1.00 49.22  ? 502  THR B OG1 1 
ATOM   10717 C  CG2 . THR B 1 502 ? 147.259 158.009 222.559 1.00 49.22  ? 502  THR B CG2 1 
ATOM   10718 N  N   . ASP B 1 503 ? 146.922 162.532 221.510 1.00 52.39  ? 503  ASP B N   1 
ATOM   10719 C  CA  . ASP B 1 503 ? 146.663 163.729 220.719 1.00 52.39  ? 503  ASP B CA  1 
ATOM   10720 C  C   . ASP B 1 503 ? 147.964 164.413 220.323 1.00 52.39  ? 503  ASP B C   1 
ATOM   10721 O  O   . ASP B 1 503 ? 148.110 164.872 219.184 1.00 52.39  ? 503  ASP B O   1 
ATOM   10722 C  CB  . ASP B 1 503 ? 145.762 164.689 221.494 1.00 52.39  ? 503  ASP B CB  1 
ATOM   10723 C  CG  . ASP B 1 503 ? 144.304 164.274 221.460 1.00 52.39  ? 503  ASP B CG  1 
ATOM   10724 O  OD1 . ASP B 1 503 ? 144.005 163.198 220.900 1.00 52.39  ? 503  ASP B OD1 1 
ATOM   10725 O  OD2 . ASP B 1 503 ? 143.458 165.022 221.993 1.00 52.39  ? 503  ASP B OD2 1 
ATOM   10726 N  N   . THR B 1 504 ? 148.923 164.489 221.248 1.00 47.58  ? 504  THR B N   1 
ATOM   10727 C  CA  . THR B 1 504 ? 150.228 165.047 220.904 1.00 47.58  ? 504  THR B CA  1 
ATOM   10728 C  C   . THR B 1 504 ? 150.922 164.205 219.839 1.00 47.58  ? 504  THR B C   1 
ATOM   10729 O  O   . THR B 1 504 ? 151.501 164.744 218.885 1.00 47.58  ? 504  THR B O   1 
ATOM   10730 C  CB  . THR B 1 504 ? 151.100 165.156 222.154 1.00 47.58  ? 504  THR B CB  1 
ATOM   10731 O  OG1 . THR B 1 504 ? 150.396 165.884 223.167 1.00 47.58  ? 504  THR B OG1 1 
ATOM   10732 C  CG2 . THR B 1 504 ? 152.400 165.874 221.832 1.00 47.58  ? 504  THR B CG2 1 
ATOM   10733 N  N   . LEU B 1 505 ? 150.865 162.877 219.980 1.00 43.43  ? 505  LEU B N   1 
ATOM   10734 C  CA  . LEU B 1 505 ? 151.469 162.003 218.977 1.00 43.43  ? 505  LEU B CA  1 
ATOM   10735 C  C   . LEU B 1 505 ? 150.806 162.168 217.614 1.00 43.43  ? 505  LEU B C   1 
ATOM   10736 O  O   . LEU B 1 505 ? 151.496 162.176 216.589 1.00 43.43  ? 505  LEU B O   1 
ATOM   10737 C  CB  . LEU B 1 505 ? 151.395 160.546 219.431 1.00 43.43  ? 505  LEU B CB  1 
ATOM   10738 C  CG  . LEU B 1 505 ? 152.181 160.166 220.687 1.00 43.43  ? 505  LEU B CG  1 
ATOM   10739 C  CD1 . LEU B 1 505 ? 152.395 158.663 220.749 1.00 43.43  ? 505  LEU B CD1 1 
ATOM   10740 C  CD2 . LEU B 1 505 ? 153.513 160.898 220.738 1.00 43.43  ? 505  LEU B CD2 1 
ATOM   10741 N  N   . ASN B 1 506 ? 149.478 162.292 217.582 1.00 42.84  ? 506  ASN B N   1 
ATOM   10742 C  CA  . ASN B 1 506 ? 148.776 162.535 216.328 1.00 42.84  ? 506  ASN B CA  1 
ATOM   10743 C  C   . ASN B 1 506 ? 149.186 163.870 215.721 1.00 42.84  ? 506  ASN B C   1 
ATOM   10744 O  O   . ASN B 1 506 ? 149.395 163.970 214.507 1.00 42.84  ? 506  ASN B O   1 
ATOM   10745 C  CB  . ASN B 1 506 ? 147.266 162.493 216.559 1.00 42.84  ? 506  ASN B CB  1 
ATOM   10746 C  CG  . ASN B 1 506 ? 146.719 161.080 216.609 1.00 42.84  ? 506  ASN B CG  1 
ATOM   10747 O  OD1 . ASN B 1 506 ? 147.373 160.132 216.181 1.00 42.84  ? 506  ASN B OD1 1 
ATOM   10748 N  ND2 . ASN B 1 506 ? 145.509 160.934 217.136 1.00 42.84  ? 506  ASN B ND2 1 
ATOM   10749 N  N   . ARG B 1 507 ? 149.305 164.908 216.553 1.00 43.88  ? 507  ARG B N   1 
ATOM   10750 C  CA  . ARG B 1 507 ? 149.774 166.206 216.088 1.00 43.88  ? 507  ARG B CA  1 
ATOM   10751 C  C   . ARG B 1 507 ? 151.192 166.151 215.544 1.00 43.88  ? 507  ARG B C   1 
ATOM   10752 O  O   . ARG B 1 507 ? 151.537 166.964 214.681 1.00 43.88  ? 507  ARG B O   1 
ATOM   10753 C  CB  . ARG B 1 507 ? 149.696 167.232 217.219 1.00 43.88  ? 507  ARG B CB  1 
ATOM   10754 C  CG  . ARG B 1 507 ? 148.399 168.020 217.256 1.00 43.88  ? 507  ARG B CG  1 
ATOM   10755 C  CD  . ARG B 1 507 ? 148.263 168.796 218.554 1.00 43.88  ? 507  ARG B CD  1 
ATOM   10756 N  NE  . ARG B 1 507 ? 146.876 168.892 218.992 1.00 43.88  ? 507  ARG B NE  1 
ATOM   10757 C  CZ  . ARG B 1 507 ? 146.484 168.832 220.257 1.00 43.88  ? 507  ARG B CZ  1 
ATOM   10758 N  NH1 . ARG B 1 507 ? 147.352 168.678 221.243 1.00 43.88  ? 507  ARG B NH1 1 
ATOM   10759 N  NH2 . ARG B 1 507 ? 145.188 168.931 220.541 1.00 43.88  ? 507  ARG B NH2 1 
ATOM   10760 N  N   . GLN B 1 508 ? 152.015 165.221 216.023 1.00 41.99  ? 508  GLN B N   1 
ATOM   10761 C  CA  . GLN B 1 508 ? 153.333 165.000 215.445 1.00 41.99  ? 508  GLN B CA  1 
ATOM   10762 C  C   . GLN B 1 508 ? 153.287 164.144 214.186 1.00 41.99  ? 508  GLN B C   1 
ATOM   10763 O  O   . GLN B 1 508 ? 154.340 163.879 213.596 1.00 41.99  ? 508  GLN B O   1 
ATOM   10764 C  CB  . GLN B 1 508 ? 154.269 164.352 216.471 1.00 41.99  ? 508  GLN B CB  1 
ATOM   10765 C  CG  . GLN B 1 508 ? 154.693 165.279 217.595 1.00 41.99  ? 508  GLN B CG  1 
ATOM   10766 C  CD  . GLN B 1 508 ? 155.884 164.748 218.366 1.00 41.99  ? 508  GLN B CD  1 
ATOM   10767 O  OE1 . GLN B 1 508 ? 156.870 164.306 217.778 1.00 41.99  ? 508  GLN B OE1 1 
ATOM   10768 N  NE2 . GLN B 1 508 ? 155.801 164.795 219.690 1.00 41.99  ? 508  GLN B NE2 1 
ATOM   10769 N  N   . GLY B 1 509 ? 152.103 163.709 213.763 1.00 40.21  ? 509  GLY B N   1 
ATOM   10770 C  CA  . GLY B 1 509 ? 151.964 162.880 212.584 1.00 40.21  ? 509  GLY B CA  1 
ATOM   10771 C  C   . GLY B 1 509 ? 152.025 161.390 212.827 1.00 40.21  ? 509  GLY B C   1 
ATOM   10772 O  O   . GLY B 1 509 ? 151.998 160.622 211.858 1.00 40.21  ? 509  GLY B O   1 
ATOM   10773 N  N   . LEU B 1 510 ? 152.105 160.956 214.080 1.00 38.13  ? 510  LEU B N   1 
ATOM   10774 C  CA  . LEU B 1 510 ? 152.169 159.543 214.424 1.00 38.13  ? 510  LEU B CA  1 
ATOM   10775 C  C   . LEU B 1 510 ? 150.756 158.988 214.543 1.00 38.13  ? 510  LEU B C   1 
ATOM   10776 O  O   . LEU B 1 510 ? 149.926 159.549 215.266 1.00 38.13  ? 510  LEU B O   1 
ATOM   10777 C  CB  . LEU B 1 510 ? 152.928 159.337 215.733 1.00 38.13  ? 510  LEU B CB  1 
ATOM   10778 C  CG  . LEU B 1 510 ? 154.437 159.564 215.718 1.00 38.13  ? 510  LEU B CG  1 
ATOM   10779 C  CD1 . LEU B 1 510 ? 154.991 159.508 217.130 1.00 38.13  ? 510  LEU B CD1 1 
ATOM   10780 C  CD2 . LEU B 1 510 ? 155.100 158.520 214.846 1.00 38.13  ? 510  LEU B CD2 1 
ATOM   10781 N  N   . ARG B 1 511 ? 150.487 157.894 213.839 1.00 36.86  ? 511  ARG B N   1 
ATOM   10782 C  CA  . ARG B 1 511 ? 149.246 157.162 214.033 1.00 36.86  ? 511  ARG B CA  1 
ATOM   10783 C  C   . ARG B 1 511 ? 149.392 156.222 215.222 1.00 36.86  ? 511  ARG B C   1 
ATOM   10784 O  O   . ARG B 1 511 ? 150.417 155.555 215.381 1.00 36.86  ? 511  ARG B O   1 
ATOM   10785 C  CB  . ARG B 1 511 ? 148.882 156.372 212.777 1.00 36.86  ? 511  ARG B CB  1 
ATOM   10786 C  CG  . ARG B 1 511 ? 148.722 157.221 211.529 1.00 36.86  ? 511  ARG B CG  1 
ATOM   10787 C  CD  . ARG B 1 511 ? 148.546 156.352 210.296 1.00 36.86  ? 511  ARG B CD  1 
ATOM   10788 N  NE  . ARG B 1 511 ? 147.374 155.492 210.403 1.00 36.86  ? 511  ARG B NE  1 
ATOM   10789 C  CZ  . ARG B 1 511 ? 147.075 154.522 209.550 1.00 36.86  ? 511  ARG B CZ  1 
ATOM   10790 N  NH1 . ARG B 1 511 ? 147.841 154.262 208.504 1.00 36.86  ? 511  ARG B NH1 1 
ATOM   10791 N  NH2 . ARG B 1 511 ? 145.980 153.795 209.752 1.00 36.86  ? 511  ARG B NH2 1 
ATOM   10792 N  N   . VAL B 1 512 ? 148.360 156.171 216.059 1.00 36.03  ? 512  VAL B N   1 
ATOM   10793 C  CA  . VAL B 1 512 ? 148.386 155.408 217.301 1.00 36.03  ? 512  VAL B CA  1 
ATOM   10794 C  C   . VAL B 1 512 ? 147.335 154.311 217.222 1.00 36.03  ? 512  VAL B C   1 
ATOM   10795 O  O   . VAL B 1 512 ? 146.166 154.581 216.922 1.00 36.03  ? 512  VAL B O   1 
ATOM   10796 C  CB  . VAL B 1 512 ? 148.147 156.315 218.521 1.00 36.03  ? 512  VAL B CB  1 
ATOM   10797 C  CG1 . VAL B 1 512 ? 147.922 155.480 219.766 1.00 36.03  ? 512  VAL B CG1 1 
ATOM   10798 C  CG2 . VAL B 1 512 ? 149.324 157.256 218.714 1.00 36.03  ? 512  VAL B CG2 1 
ATOM   10799 N  N   . VAL B 1 513 ? 147.752 153.077 217.491 1.00 39.13  ? 513  VAL B N   1 
ATOM   10800 C  CA  . VAL B 1 513 ? 146.869 151.917 217.492 1.00 39.13  ? 513  VAL B CA  1 
ATOM   10801 C  C   . VAL B 1 513 ? 147.002 151.231 218.844 1.00 39.13  ? 513  VAL B C   1 
ATOM   10802 O  O   . VAL B 1 513 ? 148.110 150.861 219.251 1.00 39.13  ? 513  VAL B O   1 
ATOM   10803 C  CB  . VAL B 1 513 ? 147.201 150.948 216.347 1.00 39.13  ? 513  VAL B CB  1 
ATOM   10804 C  CG1 . VAL B 1 513 ? 146.626 149.571 216.630 1.00 39.13  ? 513  VAL B CG1 1 
ATOM   10805 C  CG2 . VAL B 1 513 ? 146.676 151.491 215.028 1.00 39.13  ? 513  VAL B CG2 1 
ATOM   10806 N  N   . ALA B 1 514 ? 145.879 151.059 219.533 1.00 44.91  ? 514  ALA B N   1 
ATOM   10807 C  CA  . ALA B 1 514 ? 145.870 150.467 220.859 1.00 44.91  ? 514  ALA B CA  1 
ATOM   10808 C  C   . ALA B 1 514 ? 145.600 148.970 220.782 1.00 44.91  ? 514  ALA B C   1 
ATOM   10809 O  O   . ALA B 1 514 ? 144.942 148.477 219.855 1.00 44.91  ? 514  ALA B O   1 
ATOM   10810 C  CB  . ALA B 1 514 ? 144.822 151.139 221.747 1.00 44.91  ? 514  ALA B CB  1 
ATOM   10811 N  N   . VAL B 1 515 ? 146.118 148.252 221.779 1.00 44.58  ? 515  VAL B N   1 
ATOM   10812 C  CA  . VAL B 1 515 ? 146.041 146.799 221.860 1.00 44.58  ? 515  VAL B CA  1 
ATOM   10813 C  C   . VAL B 1 515 ? 145.544 146.416 223.249 1.00 44.58  ? 515  VAL B C   1 
ATOM   10814 O  O   . VAL B 1 515 ? 146.019 146.953 224.256 1.00 44.58  ? 515  VAL B O   1 
ATOM   10815 C  CB  . VAL B 1 515 ? 147.405 146.143 221.573 1.00 44.58  ? 515  VAL B CB  1 
ATOM   10816 C  CG1 . VAL B 1 515 ? 147.357 144.651 221.863 1.00 44.58  ? 515  VAL B CG1 1 
ATOM   10817 C  CG2 . VAL B 1 515 ? 147.823 146.397 220.136 1.00 44.58  ? 515  VAL B CG2 1 
ATOM   10818 N  N   . ALA B 1 516 ? 144.595 145.484 223.301 1.00 49.45  ? 516  ALA B N   1 
ATOM   10819 C  CA  . ALA B 1 516 ? 144.056 144.982 224.553 1.00 49.45  ? 516  ALA B CA  1 
ATOM   10820 C  C   . ALA B 1 516 ? 144.075 143.461 224.546 1.00 49.45  ? 516  ALA B C   1 
ATOM   10821 O  O   . ALA B 1 516 ? 143.992 142.825 223.492 1.00 49.45  ? 516  ALA B O   1 
ATOM   10822 C  CB  . ALA B 1 516 ? 142.629 145.487 224.795 1.00 49.45  ? 516  ALA B CB  1 
ATOM   10823 N  N   . THR B 1 517 ? 144.205 142.884 225.738 1.00 56.54  ? 517  THR B N   1 
ATOM   10824 C  CA  . THR B 1 517 ? 144.193 141.442 225.927 1.00 56.54  ? 517  THR B CA  1 
ATOM   10825 C  C   . THR B 1 517 ? 143.257 141.085 227.072 1.00 56.54  ? 517  THR B C   1 
ATOM   10826 O  O   . THR B 1 517 ? 143.067 141.867 228.009 1.00 56.54  ? 517  THR B O   1 
ATOM   10827 C  CB  . THR B 1 517 ? 145.595 140.888 226.223 1.00 56.54  ? 517  THR B CB  1 
ATOM   10828 O  OG1 . THR B 1 517 ? 146.108 141.490 227.417 1.00 56.54  ? 517  THR B OG1 1 
ATOM   10829 C  CG2 . THR B 1 517 ? 146.543 141.171 225.068 1.00 56.54  ? 517  THR B CG2 1 
ATOM   10830 N  N   . LYS B 1 518 ? 142.669 139.895 226.982 1.00 67.75  ? 518  LYS B N   1 
ATOM   10831 C  CA  . LYS B 1 518 ? 141.774 139.403 228.020 1.00 67.75  ? 518  LYS B CA  1 
ATOM   10832 C  C   . LYS B 1 518 ? 141.890 137.888 228.098 1.00 67.75  ? 518  LYS B C   1 
ATOM   10833 O  O   . LYS B 1 518 ? 142.184 137.224 227.102 1.00 67.75  ? 518  LYS B O   1 
ATOM   10834 C  CB  . LYS B 1 518 ? 140.323 139.816 227.747 1.00 67.75  ? 518  LYS B CB  1 
ATOM   10835 C  CG  . LYS B 1 518 ? 139.364 139.547 228.893 1.00 67.75  ? 518  LYS B CG  1 
ATOM   10836 C  CD  . LYS B 1 518 ? 137.925 139.785 228.472 1.00 67.75  ? 518  LYS B CD  1 
ATOM   10837 C  CE  . LYS B 1 518 ? 136.958 139.401 229.578 1.00 67.75  ? 518  LYS B CE  1 
ATOM   10838 N  NZ  . LYS B 1 518 ? 135.541 139.563 229.155 1.00 67.75  ? 518  LYS B NZ  1 
ATOM   10839 N  N   . TYR B 1 519 ? 141.656 137.347 229.290 1.00 73.86  ? 519  TYR B N   1 
ATOM   10840 C  CA  . TYR B 1 519 ? 141.699 135.911 229.528 1.00 73.86  ? 519  TYR B CA  1 
ATOM   10841 C  C   . TYR B 1 519 ? 140.298 135.402 229.835 1.00 73.86  ? 519  TYR B C   1 
ATOM   10842 O  O   . TYR B 1 519 ? 139.586 135.988 230.658 1.00 73.86  ? 519  TYR B O   1 
ATOM   10843 C  CB  . TYR B 1 519 ? 142.649 135.572 230.679 1.00 73.86  ? 519  TYR B CB  1 
ATOM   10844 C  CG  . TYR B 1 519 ? 144.110 135.729 230.330 1.00 73.86  ? 519  TYR B CG  1 
ATOM   10845 C  CD1 . TYR B 1 519 ? 144.801 134.715 229.682 1.00 73.86  ? 519  TYR B CD1 1 
ATOM   10846 C  CD2 . TYR B 1 519 ? 144.799 136.891 230.649 1.00 73.86  ? 519  TYR B CD2 1 
ATOM   10847 C  CE1 . TYR B 1 519 ? 146.137 134.853 229.360 1.00 73.86  ? 519  TYR B CE1 1 
ATOM   10848 C  CE2 . TYR B 1 519 ? 146.136 137.039 230.331 1.00 73.86  ? 519  TYR B CE2 1 
ATOM   10849 C  CZ  . TYR B 1 519 ? 146.800 136.016 229.686 1.00 73.86  ? 519  TYR B CZ  1 
ATOM   10850 O  OH  . TYR B 1 519 ? 148.131 136.158 229.368 1.00 73.86  ? 519  TYR B OH  1 
ATOM   10851 N  N   . LEU B 1 520 ? 139.906 134.319 229.172 1.00 79.73  ? 520  LEU B N   1 
ATOM   10852 C  CA  . LEU B 1 520 ? 138.601 133.709 229.358 1.00 79.73  ? 520  LEU B CA  1 
ATOM   10853 C  C   . LEU B 1 520 ? 138.751 132.207 229.547 1.00 79.73  ? 520  LEU B C   1 
ATOM   10854 O  O   . LEU B 1 520 ? 139.747 131.618 229.115 1.00 79.73  ? 520  LEU B O   1 
ATOM   10855 C  CB  . LEU B 1 520 ? 137.681 133.985 228.158 1.00 79.73  ? 520  LEU B CB  1 
ATOM   10856 C  CG  . LEU B 1 520 ? 137.098 135.395 228.040 1.00 79.73  ? 520  LEU B CG  1 
ATOM   10857 C  CD1 . LEU B 1 520 ? 138.035 136.312 227.270 1.00 79.73  ? 520  LEU B CD1 1 
ATOM   10858 C  CD2 . LEU B 1 520 ? 135.724 135.354 227.389 1.00 79.73  ? 520  LEU B CD2 1 
ATOM   10859 N  N   . PRO B 1 521 ? 137.792 131.567 230.213 1.00 84.46  ? 521  PRO B N   1 
ATOM   10860 C  CA  . PRO B 1 521 ? 137.810 130.103 230.295 1.00 84.46  ? 521  PRO B CA  1 
ATOM   10861 C  C   . PRO B 1 521 ? 137.577 129.473 228.932 1.00 84.46  ? 521  PRO B C   1 
ATOM   10862 O  O   . PRO B 1 521 ? 136.921 130.046 228.058 1.00 84.46  ? 521  PRO B O   1 
ATOM   10863 C  CB  . PRO B 1 521 ? 136.663 129.784 231.260 1.00 84.46  ? 521  PRO B CB  1 
ATOM   10864 C  CG  . PRO B 1 521 ? 135.776 130.983 231.210 1.00 84.46  ? 521  PRO B CG  1 
ATOM   10865 C  CD  . PRO B 1 521 ? 136.684 132.151 230.988 1.00 84.46  ? 521  PRO B CD  1 
ATOM   10866 N  N   . ALA B 1 522 ? 138.132 128.275 228.756 1.00 87.99  ? 522  ALA B N   1 
ATOM   10867 C  CA  . ALA B 1 522 ? 137.999 127.570 227.489 1.00 87.99  ? 522  ALA B CA  1 
ATOM   10868 C  C   . ALA B 1 522 ? 136.539 127.236 227.211 1.00 87.99  ? 522  ALA B C   1 
ATOM   10869 O  O   . ALA B 1 522 ? 135.795 126.825 228.106 1.00 87.99  ? 522  ALA B O   1 
ATOM   10870 C  CB  . ALA B 1 522 ? 138.839 126.294 227.501 1.00 87.99  ? 522  ALA B CB  1 
ATOM   10871 N  N   . ARG B 1 523 ? 136.130 127.415 225.957 1.00 85.22  ? 523  ARG B N   1 
ATOM   10872 C  CA  . ARG B 1 523 ? 134.759 127.149 225.553 1.00 85.22  ? 523  ARG B CA  1 
ATOM   10873 C  C   . ARG B 1 523 ? 134.747 126.694 224.101 1.00 85.22  ? 523  ARG B C   1 
ATOM   10874 O  O   . ARG B 1 523 ? 135.676 126.973 223.340 1.00 85.22  ? 523  ARG B O   1 
ATOM   10875 C  CB  . ARG B 1 523 ? 133.868 128.383 225.742 1.00 85.22  ? 523  ARG B CB  1 
ATOM   10876 C  CG  . ARG B 1 523 ? 133.947 129.395 224.612 1.00 85.22  ? 523  ARG B CG  1 
ATOM   10877 C  CD  . ARG B 1 523 ? 133.427 130.751 225.059 1.00 85.22  ? 523  ARG B CD  1 
ATOM   10878 N  NE  . ARG B 1 523 ? 133.039 131.590 223.932 1.00 85.22  ? 523  ARG B NE  1 
ATOM   10879 C  CZ  . ARG B 1 523 ? 132.625 132.845 224.042 1.00 85.22  ? 523  ARG B CZ  1 
ATOM   10880 N  NH1 . ARG B 1 523 ? 132.534 133.442 225.219 1.00 85.22  ? 523  ARG B NH1 1 
ATOM   10881 N  NH2 . ARG B 1 523 ? 132.294 133.518 222.944 1.00 85.22  ? 523  ARG B NH2 1 
ATOM   10882 N  N   . GLU B 1 524 ? 133.682 125.984 223.729 1.00 90.65  ? 524  GLU B N   1 
ATOM   10883 C  CA  . GLU B 1 524 ? 133.567 125.425 222.388 1.00 90.65  ? 524  GLU B CA  1 
ATOM   10884 C  C   . GLU B 1 524 ? 132.896 126.373 221.405 1.00 90.65  ? 524  GLU B C   1 
ATOM   10885 O  O   . GLU B 1 524 ? 133.183 126.312 220.204 1.00 90.65  ? 524  GLU B O   1 
ATOM   10886 C  CB  . GLU B 1 524 ? 132.788 124.107 222.434 1.00 90.65  ? 524  GLU B CB  1 
ATOM   10887 C  CG  . GLU B 1 524 ? 133.502 122.989 223.175 1.00 90.65  ? 524  GLU B CG  1 
ATOM   10888 C  CD  . GLU B 1 524 ? 134.738 122.500 222.446 1.00 90.65  ? 524  GLU B CD  1 
ATOM   10889 O  OE1 . GLU B 1 524 ? 134.745 122.529 221.198 1.00 90.65  ? 524  GLU B OE1 1 
ATOM   10890 O  OE2 . GLU B 1 524 ? 135.703 122.087 223.124 1.00 90.65  ? 524  GLU B OE2 1 
ATOM   10891 N  N   . GLY B 1 525 ? 132.010 127.244 221.883 1.00 85.10  ? 525  GLY B N   1 
ATOM   10892 C  CA  . GLY B 1 525 ? 131.308 128.142 220.992 1.00 85.10  ? 525  GLY B CA  1 
ATOM   10893 C  C   . GLY B 1 525 ? 132.214 129.199 220.393 1.00 85.10  ? 525  GLY B C   1 
ATOM   10894 O  O   . GLY B 1 525 ? 133.245 129.577 220.951 1.00 85.10  ? 525  GLY B O   1 
ATOM   10895 N  N   . ASP B 1 526 ? 131.810 129.682 219.222 1.00 81.43  ? 526  ASP B N   1 
ATOM   10896 C  CA  . ASP B 1 526 ? 132.563 130.724 218.541 1.00 81.43  ? 526  ASP B CA  1 
ATOM   10897 C  C   . ASP B 1 526 ? 132.451 132.046 219.291 1.00 81.43  ? 526  ASP B C   1 
ATOM   10898 O  O   . ASP B 1 526 ? 131.431 132.351 219.914 1.00 81.43  ? 526  ASP B O   1 
ATOM   10899 C  CB  . ASP B 1 526 ? 132.066 130.892 217.106 1.00 81.43  ? 526  ASP B CB  1 
ATOM   10900 C  CG  . ASP B 1 526 ? 132.615 129.833 216.171 1.00 81.43  ? 526  ASP B CG  1 
ATOM   10901 O  OD1 . ASP B 1 526 ? 133.563 129.123 216.565 1.00 81.43  ? 526  ASP B OD1 1 
ATOM   10902 O  OD2 . ASP B 1 526 ? 132.098 129.711 215.040 1.00 81.43  ? 526  ASP B OD2 1 
ATOM   10903 N  N   . TYR B 1 527 ? 133.519 132.834 219.225 1.00 77.05  ? 527  TYR B N   1 
ATOM   10904 C  CA  . TYR B 1 527 ? 133.564 134.127 219.892 1.00 77.05  ? 527  TYR B CA  1 
ATOM   10905 C  C   . TYR B 1 527 ? 132.909 135.192 219.024 1.00 77.05  ? 527  TYR B C   1 
ATOM   10906 O  O   . TYR B 1 527 ? 133.223 135.326 217.838 1.00 77.05  ? 527  TYR B O   1 
ATOM   10907 C  CB  . TYR B 1 527 ? 135.009 134.516 220.211 1.00 77.05  ? 527  TYR B CB  1 
ATOM   10908 C  CG  . TYR B 1 527 ? 135.673 133.597 221.211 1.00 77.05  ? 527  TYR B CG  1 
ATOM   10909 C  CD1 . TYR B 1 527 ? 136.282 132.417 220.803 1.00 77.05  ? 527  TYR B CD1 1 
ATOM   10910 C  CD2 . TYR B 1 527 ? 135.692 133.909 222.564 1.00 77.05  ? 527  TYR B CD2 1 
ATOM   10911 C  CE1 . TYR B 1 527 ? 136.887 131.572 221.713 1.00 77.05  ? 527  TYR B CE1 1 
ATOM   10912 C  CE2 . TYR B 1 527 ? 136.297 133.071 223.481 1.00 77.05  ? 527  TYR B CE2 1 
ATOM   10913 C  CZ  . TYR B 1 527 ? 136.893 131.905 223.051 1.00 77.05  ? 527  TYR B CZ  1 
ATOM   10914 O  OH  . TYR B 1 527 ? 137.497 131.068 223.960 1.00 77.05  ? 527  TYR B OH  1 
ATOM   10915 N  N   . GLN B 1 528 ? 131.995 135.946 219.624 1.00 74.85  ? 528  GLN B N   1 
ATOM   10916 C  CA  . GLN B 1 528 ? 131.253 136.992 218.939 1.00 74.85  ? 528  GLN B CA  1 
ATOM   10917 C  C   . GLN B 1 528 ? 131.786 138.358 219.352 1.00 74.85  ? 528  GLN B C   1 
ATOM   10918 O  O   . GLN B 1 528 ? 132.718 138.475 220.152 1.00 74.85  ? 528  GLN B O   1 
ATOM   10919 C  CB  . GLN B 1 528 ? 129.751 136.896 219.242 1.00 74.85  ? 528  GLN B CB  1 
ATOM   10920 C  CG  . GLN B 1 528 ? 129.224 135.474 219.355 1.00 74.85  ? 528  GLN B CG  1 
ATOM   10921 C  CD  . GLN B 1 528 ? 129.164 134.763 218.019 1.00 74.85  ? 528  GLN B CD  1 
ATOM   10922 O  OE1 . GLN B 1 528 ? 129.820 133.741 217.816 1.00 74.85  ? 528  GLN B OE1 1 
ATOM   10923 N  NE2 . GLN B 1 528 ? 128.371 135.298 217.098 1.00 74.85  ? 528  GLN B NE2 1 
ATOM   10924 N  N   . ARG B 1 529 ? 131.177 139.404 218.787 1.00 72.79  ? 529  ARG B N   1 
ATOM   10925 C  CA  . ARG B 1 529 ? 131.591 140.765 219.105 1.00 72.79  ? 529  ARG B CA  1 
ATOM   10926 C  C   . ARG B 1 529 ? 131.290 141.142 220.548 1.00 72.79  ? 529  ARG B C   1 
ATOM   10927 O  O   . ARG B 1 529 ? 131.887 142.093 221.065 1.00 72.79  ? 529  ARG B O   1 
ATOM   10928 C  CB  . ARG B 1 529 ? 130.912 141.759 218.162 1.00 72.79  ? 529  ARG B CB  1 
ATOM   10929 C  CG  . ARG B 1 529 ? 130.947 141.358 216.699 1.00 72.79  ? 529  ARG B CG  1 
ATOM   10930 C  CD  . ARG B 1 529 ? 130.538 142.521 215.810 1.00 72.79  ? 529  ARG B CD  1 
ATOM   10931 N  NE  . ARG B 1 529 ? 129.428 143.274 216.379 1.00 72.79  ? 529  ARG B NE  1 
ATOM   10932 C  CZ  . ARG B 1 529 ? 128.962 144.413 215.885 1.00 72.79  ? 529  ARG B CZ  1 
ATOM   10933 N  NH1 . ARG B 1 529 ? 129.496 144.970 214.810 1.00 72.79  ? 529  ARG B NH1 1 
ATOM   10934 N  NH2 . ARG B 1 529 ? 127.936 145.010 216.486 1.00 72.79  ? 529  ARG B NH2 1 
ATOM   10935 N  N   . ALA B 1 530 ? 130.381 140.423 221.210 1.00 72.78  ? 530  ALA B N   1 
ATOM   10936 C  CA  . ALA B 1 530 ? 130.034 140.761 222.586 1.00 72.78  ? 530  ALA B CA  1 
ATOM   10937 C  C   . ALA B 1 530 ? 131.152 140.405 223.556 1.00 72.78  ? 530  ALA B C   1 
ATOM   10938 O  O   . ALA B 1 530 ? 131.162 140.891 224.692 1.00 72.78  ? 530  ALA B O   1 
ATOM   10939 C  CB  . ALA B 1 530 ? 128.739 140.058 222.990 1.00 72.78  ? 530  ALA B CB  1 
ATOM   10940 N  N   . ASP B 1 531 ? 132.095 139.566 223.135 1.00 74.84  ? 531  ASP B N   1 
ATOM   10941 C  CA  . ASP B 1 531 ? 133.202 139.154 223.993 1.00 74.84  ? 531  ASP B CA  1 
ATOM   10942 C  C   . ASP B 1 531 ? 134.239 140.249 224.199 1.00 74.84  ? 531  ASP B C   1 
ATOM   10943 O  O   . ASP B 1 531 ? 135.117 140.085 225.055 1.00 74.84  ? 531  ASP B O   1 
ATOM   10944 C  CB  . ASP B 1 531 ? 133.871 137.907 223.412 1.00 74.84  ? 531  ASP B CB  1 
ATOM   10945 C  CG  . ASP B 1 531 ? 132.928 136.723 223.339 1.00 74.84  ? 531  ASP B CG  1 
ATOM   10946 O  OD1 . ASP B 1 531 ? 132.463 136.262 224.402 1.00 74.84  ? 531  ASP B OD1 1 
ATOM   10947 O  OD2 . ASP B 1 531 ? 132.649 136.256 222.215 1.00 74.84  ? 531  ASP B OD2 1 
ATOM   10948 N  N   . GLU B 1 532 ? 134.172 141.349 223.454 1.00 71.17  ? 532  GLU B N   1 
ATOM   10949 C  CA  . GLU B 1 532 ? 135.131 142.443 223.595 1.00 71.17  ? 532  GLU B CA  1 
ATOM   10950 C  C   . GLU B 1 532 ? 134.653 143.410 224.678 1.00 71.17  ? 532  GLU B C   1 
ATOM   10951 O  O   . GLU B 1 532 ? 134.151 144.502 224.412 1.00 71.17  ? 532  GLU B O   1 
ATOM   10952 C  CB  . GLU B 1 532 ? 135.326 143.150 222.257 1.00 71.17  ? 532  GLU B CB  1 
ATOM   10953 C  CG  . GLU B 1 532 ? 135.865 142.257 221.155 1.00 71.17  ? 532  GLU B CG  1 
ATOM   10954 C  CD  . GLU B 1 532 ? 135.958 142.973 219.824 1.00 71.17  ? 532  GLU B CD  1 
ATOM   10955 O  OE1 . GLU B 1 532 ? 135.688 144.191 219.783 1.00 71.17  ? 532  GLU B OE1 1 
ATOM   10956 O  OE2 . GLU B 1 532 ? 136.298 142.316 218.817 1.00 71.17  ? 532  GLU B OE2 1 
ATOM   10957 N  N   . SER B 1 533 ? 134.819 142.978 225.926 1.00 69.12  ? 533  SER B N   1 
ATOM   10958 C  CA  . SER B 1 533 ? 134.416 143.783 227.068 1.00 69.12  ? 533  SER B CA  1 
ATOM   10959 C  C   . SER B 1 533 ? 135.330 143.479 228.245 1.00 69.12  ? 533  SER B C   1 
ATOM   10960 O  O   . SER B 1 533 ? 135.859 142.370 228.366 1.00 69.12  ? 533  SER B O   1 
ATOM   10961 C  CB  . SER B 1 533 ? 132.955 143.525 227.450 1.00 69.12  ? 533  SER B CB  1 
ATOM   10962 O  OG  . SER B 1 533 ? 132.660 142.139 227.420 1.00 69.12  ? 533  SER B OG  1 
ATOM   10963 N  N   . ASP B 1 534 ? 135.501 144.477 229.112 1.00 69.65  ? 534  ASP B N   1 
ATOM   10964 C  CA  . ASP B 1 534 ? 136.338 144.364 230.307 1.00 69.65  ? 534  ASP B CA  1 
ATOM   10965 C  C   . ASP B 1 534 ? 137.753 143.915 229.945 1.00 69.65  ? 534  ASP B C   1 
ATOM   10966 O  O   . ASP B 1 534 ? 138.347 143.049 230.590 1.00 69.65  ? 534  ASP B O   1 
ATOM   10967 C  CB  . ASP B 1 534 ? 135.704 143.421 231.330 1.00 69.65  ? 534  ASP B CB  1 
ATOM   10968 C  CG  . ASP B 1 534 ? 134.373 143.930 231.843 1.00 69.65  ? 534  ASP B CG  1 
ATOM   10969 O  OD1 . ASP B 1 534 ? 134.200 145.164 231.925 1.00 69.65  ? 534  ASP B OD1 1 
ATOM   10970 O  OD2 . ASP B 1 534 ? 133.499 143.098 232.162 1.00 69.65  ? 534  ASP B OD2 1 
ATOM   10971 N  N   . LEU B 1 535 ? 138.293 144.521 228.893 1.00 63.59  ? 535  LEU B N   1 
ATOM   10972 C  CA  . LEU B 1 535 ? 139.608 144.162 228.393 1.00 63.59  ? 535  LEU B CA  1 
ATOM   10973 C  C   . LEU B 1 535 ? 140.703 144.797 229.247 1.00 63.59  ? 535  LEU B C   1 
ATOM   10974 O  O   . LEU B 1 535 ? 140.455 145.668 230.086 1.00 63.59  ? 535  LEU B O   1 
ATOM   10975 C  CB  . LEU B 1 535 ? 139.754 144.594 226.936 1.00 63.59  ? 535  LEU B CB  1 
ATOM   10976 C  CG  . LEU B 1 535 ? 138.718 144.016 225.973 1.00 63.59  ? 535  LEU B CG  1 
ATOM   10977 C  CD1 . LEU B 1 535 ? 138.791 144.719 224.632 1.00 63.59  ? 535  LEU B CD1 1 
ATOM   10978 C  CD2 . LEU B 1 535 ? 138.921 142.524 225.807 1.00 63.59  ? 535  LEU B CD2 1 
ATOM   10979 N  N   . ILE B 1 536 ? 141.934 144.345 229.025 1.00 58.80  ? 536  ILE B N   1 
ATOM   10980 C  CA  . ILE B 1 536 ? 143.115 144.889 229.685 1.00 58.80  ? 536  ILE B CA  1 
ATOM   10981 C  C   . ILE B 1 536 ? 143.959 145.579 228.623 1.00 58.80  ? 536  ILE B C   1 
ATOM   10982 O  O   . ILE B 1 536 ? 144.515 144.918 227.740 1.00 58.80  ? 536  ILE B O   1 
ATOM   10983 C  CB  . ILE B 1 536 ? 143.920 143.795 230.401 1.00 58.80  ? 536  ILE B CB  1 
ATOM   10984 C  CG1 . ILE B 1 536 ? 143.128 143.233 231.583 1.00 58.80  ? 536  ILE B CG1 1 
ATOM   10985 C  CG2 . ILE B 1 536 ? 145.256 144.340 230.872 1.00 58.80  ? 536  ILE B CG2 1 
ATOM   10986 C  CD1 . ILE B 1 536 ? 143.751 142.000 232.200 1.00 58.80  ? 536  ILE B CD1 1 
ATOM   10987 N  N   . LEU B 1 537 ? 144.060 146.903 228.709 1.00 54.34  ? 537  LEU B N   1 
ATOM   10988 C  CA  . LEU B 1 537 ? 144.791 147.685 227.716 1.00 54.34  ? 537  LEU B CA  1 
ATOM   10989 C  C   . LEU B 1 537 ? 146.286 147.498 227.942 1.00 54.34  ? 537  LEU B C   1 
ATOM   10990 O  O   . LEU B 1 537 ? 146.836 147.989 228.933 1.00 54.34  ? 537  LEU B O   1 
ATOM   10991 C  CB  . LEU B 1 537 ? 144.401 149.157 227.807 1.00 54.34  ? 537  LEU B CB  1 
ATOM   10992 C  CG  . LEU B 1 537 ? 145.293 150.160 227.071 1.00 54.34  ? 537  LEU B CG  1 
ATOM   10993 C  CD1 . LEU B 1 537 ? 145.105 150.050 225.568 1.00 54.34  ? 537  LEU B CD1 1 
ATOM   10994 C  CD2 . LEU B 1 537 ? 145.014 151.576 227.549 1.00 54.34  ? 537  LEU B CD2 1 
ATOM   10995 N  N   . GLU B 1 538 ? 146.949 146.782 227.031 1.00 53.31  ? 538  GLU B N   1 
ATOM   10996 C  CA  . GLU B 1 538 ? 148.379 146.550 227.199 1.00 53.31  ? 538  GLU B CA  1 
ATOM   10997 C  C   . GLU B 1 538 ? 149.191 147.793 226.856 1.00 53.31  ? 538  GLU B C   1 
ATOM   10998 O  O   . GLU B 1 538 ? 150.192 148.086 227.519 1.00 53.31  ? 538  GLU B O   1 
ATOM   10999 C  CB  . GLU B 1 538 ? 148.826 145.367 226.339 1.00 53.31  ? 538  GLU B CB  1 
ATOM   11000 C  CG  . GLU B 1 538 ? 148.140 144.052 226.675 1.00 53.31  ? 538  GLU B CG  1 
ATOM   11001 C  CD  . GLU B 1 538 ? 148.708 143.381 227.914 1.00 53.31  ? 538  GLU B CD  1 
ATOM   11002 O  OE1 . GLU B 1 538 ? 149.521 144.009 228.623 1.00 53.31  ? 538  GLU B OE1 1 
ATOM   11003 O  OE2 . GLU B 1 538 ? 148.338 142.219 228.179 1.00 53.31  ? 538  GLU B OE2 1 
ATOM   11004 N  N   . GLY B 1 539 ? 148.776 148.531 225.835 1.00 47.51  ? 539  GLY B N   1 
ATOM   11005 C  CA  . GLY B 1 539 ? 149.485 149.732 225.436 1.00 47.51  ? 539  GLY B CA  1 
ATOM   11006 C  C   . GLY B 1 539 ? 149.076 150.140 224.031 1.00 47.51  ? 539  GLY B C   1 
ATOM   11007 O  O   . GLY B 1 539 ? 148.089 149.646 223.491 1.00 47.51  ? 539  GLY B O   1 
ATOM   11008 N  N   . TYR B 1 540 ? 149.862 151.049 223.460 1.00 41.65  ? 540  TYR B N   1 
ATOM   11009 C  CA  . TYR B 1 540 ? 149.597 151.535 222.115 1.00 41.65  ? 540  TYR B CA  1 
ATOM   11010 C  C   . TYR B 1 540 ? 150.902 151.597 221.339 1.00 41.65  ? 540  TYR B C   1 
ATOM   11011 O  O   . TYR B 1 540 ? 151.980 151.778 221.910 1.00 41.65  ? 540  TYR B O   1 
ATOM   11012 C  CB  . TYR B 1 540 ? 148.914 152.908 222.135 1.00 41.65  ? 540  TYR B CB  1 
ATOM   11013 C  CG  . TYR B 1 540 ? 149.644 153.950 222.951 1.00 41.65  ? 540  TYR B CG  1 
ATOM   11014 C  CD1 . TYR B 1 540 ? 150.691 154.681 222.407 1.00 41.65  ? 540  TYR B CD1 1 
ATOM   11015 C  CD2 . TYR B 1 540 ? 149.283 154.204 224.266 1.00 41.65  ? 540  TYR B CD2 1 
ATOM   11016 C  CE1 . TYR B 1 540 ? 151.359 155.632 223.150 1.00 41.65  ? 540  TYR B CE1 1 
ATOM   11017 C  CE2 . TYR B 1 540 ? 149.944 155.154 225.017 1.00 41.65  ? 540  TYR B CE2 1 
ATOM   11018 C  CZ  . TYR B 1 540 ? 150.981 155.865 224.454 1.00 41.65  ? 540  TYR B CZ  1 
ATOM   11019 O  OH  . TYR B 1 540 ? 151.644 156.812 225.198 1.00 41.65  ? 540  TYR B OH  1 
ATOM   11020 N  N   . ILE B 1 541 ? 150.789 151.450 220.024 1.00 34.88  ? 541  ILE B N   1 
ATOM   11021 C  CA  . ILE B 1 541 ? 151.931 151.488 219.119 1.00 34.88  ? 541  ILE B CA  1 
ATOM   11022 C  C   . ILE B 1 541 ? 151.778 152.709 218.226 1.00 34.88  ? 541  ILE B C   1 
ATOM   11023 O  O   . ILE B 1 541 ? 150.772 152.848 217.519 1.00 34.88  ? 541  ILE B O   1 
ATOM   11024 C  CB  . ILE B 1 541 ? 152.034 150.206 218.280 1.00 34.88  ? 541  ILE B CB  1 
ATOM   11025 C  CG1 . ILE B 1 541 ? 152.145 148.982 219.188 1.00 34.88  ? 541  ILE B CG1 1 
ATOM   11026 C  CG2 . ILE B 1 541 ? 153.223 150.281 217.340 1.00 34.88  ? 541  ILE B CG2 1 
ATOM   11027 C  CD1 . ILE B 1 541 ? 152.326 147.688 218.435 1.00 34.88  ? 541  ILE B CD1 1 
ATOM   11028 N  N   . ALA B 1 542 ? 152.770 153.592 218.257 1.00 35.74  ? 542  ALA B N   1 
ATOM   11029 C  CA  . ALA B 1 542 ? 152.784 154.794 217.434 1.00 35.74  ? 542  ALA B CA  1 
ATOM   11030 C  C   . ALA B 1 542 ? 153.757 154.579 216.285 1.00 35.74  ? 542  ALA B C   1 
ATOM   11031 O  O   . ALA B 1 542 ? 154.915 154.216 216.510 1.00 35.74  ? 542  ALA B O   1 
ATOM   11032 C  CB  . ALA B 1 542 ? 153.180 156.019 218.257 1.00 35.74  ? 542  ALA B CB  1 
ATOM   11033 N  N   . PHE B 1 543 ? 153.288 154.797 215.060 1.00 35.83  ? 543  PHE B N   1 
ATOM   11034 C  CA  . PHE B 1 543 ? 154.102 154.592 213.873 1.00 35.83  ? 543  PHE B CA  1 
ATOM   11035 C  C   . PHE B 1 543 ? 153.965 155.785 212.939 1.00 35.83  ? 543  PHE B C   1 
ATOM   11036 O  O   . PHE B 1 543 ? 152.902 156.406 212.852 1.00 35.83  ? 543  PHE B O   1 
ATOM   11037 C  CB  . PHE B 1 543 ? 153.711 153.301 213.141 1.00 35.83  ? 543  PHE B CB  1 
ATOM   11038 C  CG  . PHE B 1 543 ? 152.246 153.195 212.831 1.00 35.83  ? 543  PHE B CG  1 
ATOM   11039 C  CD1 . PHE B 1 543 ? 151.365 152.654 213.751 1.00 35.83  ? 543  PHE B CD1 1 
ATOM   11040 C  CD2 . PHE B 1 543 ? 151.751 153.623 211.612 1.00 35.83  ? 543  PHE B CD2 1 
ATOM   11041 C  CE1 . PHE B 1 543 ? 150.018 152.557 213.464 1.00 35.83  ? 543  PHE B CE1 1 
ATOM   11042 C  CE2 . PHE B 1 543 ? 150.406 153.522 211.321 1.00 35.83  ? 543  PHE B CE2 1 
ATOM   11043 C  CZ  . PHE B 1 543 ? 149.539 152.987 212.247 1.00 35.83  ? 543  PHE B CZ  1 
ATOM   11044 N  N   . LEU B 1 544 ? 155.051 156.100 212.238 1.00 34.76  ? 544  LEU B N   1 
ATOM   11045 C  CA  . LEU B 1 544 ? 155.091 157.230 211.317 1.00 34.76  ? 544  LEU B CA  1 
ATOM   11046 C  C   . LEU B 1 544 ? 155.030 156.720 209.886 1.00 34.76  ? 544  LEU B C   1 
ATOM   11047 O  O   . LEU B 1 544 ? 155.820 155.852 209.494 1.00 34.76  ? 544  LEU B O   1 
ATOM   11048 C  CB  . LEU B 1 544 ? 156.348 158.075 211.515 1.00 34.76  ? 544  LEU B CB  1 
ATOM   11049 C  CG  . LEU B 1 544 ? 156.454 159.219 210.502 1.00 34.76  ? 544  LEU B CG  1 
ATOM   11050 C  CD1 . LEU B 1 544 ? 155.228 160.115 210.576 1.00 34.76  ? 544  LEU B CD1 1 
ATOM   11051 C  CD2 . LEU B 1 544 ? 157.716 160.024 210.709 1.00 34.76  ? 544  LEU B CD2 1 
ATOM   11052 N  N   . ASP B 1 545 ? 154.093 157.267 209.113 1.00 38.44  ? 545  ASP B N   1 
ATOM   11053 C  CA  . ASP B 1 545 ? 153.947 156.969 207.693 1.00 38.44  ? 545  ASP B CA  1 
ATOM   11054 C  C   . ASP B 1 545 ? 154.386 158.190 206.899 1.00 38.44  ? 545  ASP B C   1 
ATOM   11055 O  O   . ASP B 1 545 ? 153.643 159.182 206.823 1.00 38.44  ? 545  ASP B O   1 
ATOM   11056 C  CB  . ASP B 1 545 ? 152.496 156.605 207.368 1.00 38.44  ? 545  ASP B CB  1 
ATOM   11057 C  CG  . ASP B 1 545 ? 152.341 156.025 205.985 1.00 38.44  ? 545  ASP B CG  1 
ATOM   11058 O  OD1 . ASP B 1 545 ? 153.261 155.312 205.534 1.00 38.44  ? 545  ASP B OD1 1 
ATOM   11059 O  OD2 . ASP B 1 545 ? 151.295 156.277 205.352 1.00 38.44  ? 545  ASP B OD2 1 
ATOM   11060 N  N   . PRO B 1 546 ? 155.569 158.177 206.295 1.00 37.56  ? 546  PRO B N   1 
ATOM   11061 C  CA  . PRO B 1 546 ? 156.106 159.394 205.685 1.00 37.56  ? 546  PRO B CA  1 
ATOM   11062 C  C   . PRO B 1 546 ? 155.406 159.712 204.377 1.00 37.56  ? 546  PRO B C   1 
ATOM   11063 O  O   . PRO B 1 546 ? 155.056 158.803 203.610 1.00 37.56  ? 546  PRO B O   1 
ATOM   11064 C  CB  . PRO B 1 546 ? 157.582 159.046 205.455 1.00 37.56  ? 546  PRO B CB  1 
ATOM   11065 C  CG  . PRO B 1 546 ? 157.591 157.570 205.282 1.00 37.56  ? 546  PRO B CG  1 
ATOM   11066 C  CD  . PRO B 1 546 ? 156.436 157.008 206.071 1.00 37.56  ? 546  PRO B CD  1 
ATOM   11067 N  N   . PRO B 1 547 ? 155.181 160.991 204.089 1.00 37.66  ? 547  PRO B N   1 
ATOM   11068 C  CA  . PRO B 1 547 ? 154.606 161.362 202.794 1.00 37.66  ? 547  PRO B CA  1 
ATOM   11069 C  C   . PRO B 1 547 ? 155.565 161.058 201.656 1.00 37.66  ? 547  PRO B C   1 
ATOM   11070 O  O   . PRO B 1 547 ? 156.787 161.097 201.813 1.00 37.66  ? 547  PRO B O   1 
ATOM   11071 C  CB  . PRO B 1 547 ? 154.365 162.870 202.930 1.00 37.66  ? 547  PRO B CB  1 
ATOM   11072 C  CG  . PRO B 1 547 ? 155.326 163.310 203.981 1.00 37.66  ? 547  PRO B CG  1 
ATOM   11073 C  CD  . PRO B 1 547 ? 155.432 162.165 204.943 1.00 37.66  ? 547  PRO B CD  1 
ATOM   11074 N  N   . LYS B 1 548 ? 154.991 160.745 200.497 1.00 36.27  ? 548  LYS B N   1 
ATOM   11075 C  CA  . LYS B 1 548 ? 155.798 160.459 199.321 1.00 36.27  ? 548  LYS B CA  1 
ATOM   11076 C  C   . LYS B 1 548 ? 156.553 161.705 198.875 1.00 36.27  ? 548  LYS B C   1 
ATOM   11077 O  O   . LYS B 1 548 ? 156.079 162.835 199.022 1.00 36.27  ? 548  LYS B O   1 
ATOM   11078 C  CB  . LYS B 1 548 ? 154.922 159.943 198.181 1.00 36.27  ? 548  LYS B CB  1 
ATOM   11079 C  CG  . LYS B 1 548 ? 154.815 158.432 198.109 1.00 36.27  ? 548  LYS B CG  1 
ATOM   11080 C  CD  . LYS B 1 548 ? 153.943 158.003 196.942 1.00 36.27  ? 548  LYS B CD  1 
ATOM   11081 C  CE  . LYS B 1 548 ? 153.727 156.500 196.937 1.00 36.27  ? 548  LYS B CE  1 
ATOM   11082 N  NZ  . LYS B 1 548 ? 152.702 156.098 195.938 1.00 36.27  ? 548  LYS B NZ  1 
ATOM   11083 N  N   . GLU B 1 549 ? 157.751 161.486 198.329 1.00 42.13  ? 549  GLU B N   1 
ATOM   11084 C  CA  . GLU B 1 549 ? 158.577 162.600 197.877 1.00 42.13  ? 549  GLU B CA  1 
ATOM   11085 C  C   . GLU B 1 549 ? 157.938 163.344 196.711 1.00 42.13  ? 549  GLU B C   1 
ATOM   11086 O  O   . GLU B 1 549 ? 158.135 164.556 196.568 1.00 42.13  ? 549  GLU B O   1 
ATOM   11087 C  CB  . GLU B 1 549 ? 159.966 162.095 197.490 1.00 42.13  ? 549  GLU B CB  1 
ATOM   11088 C  CG  . GLU B 1 549 ? 160.970 163.193 197.188 1.00 42.13  ? 549  GLU B CG  1 
ATOM   11089 C  CD  . GLU B 1 549 ? 161.084 163.483 195.705 1.00 42.13  ? 549  GLU B CD  1 
ATOM   11090 O  OE1 . GLU B 1 549 ? 160.865 162.555 194.898 1.00 42.13  ? 549  GLU B OE1 1 
ATOM   11091 O  OE2 . GLU B 1 549 ? 161.393 164.639 195.346 1.00 42.13  ? 549  GLU B OE2 1 
ATOM   11092 N  N   . THR B 1 550 ? 157.169 162.647 195.877 1.00 39.85  ? 550  THR B N   1 
ATOM   11093 C  CA  . THR B 1 550 ? 156.579 163.227 194.680 1.00 39.85  ? 550  THR B CA  1 
ATOM   11094 C  C   . THR B 1 550 ? 155.149 163.706 194.893 1.00 39.85  ? 550  THR B C   1 
ATOM   11095 O  O   . THR B 1 550 ? 154.496 164.114 193.927 1.00 39.85  ? 550  THR B O   1 
ATOM   11096 C  CB  . THR B 1 550 ? 156.618 162.217 193.531 1.00 39.85  ? 550  THR B CB  1 
ATOM   11097 O  OG1 . THR B 1 550 ? 156.161 160.942 194.000 1.00 39.85  ? 550  THR B OG1 1 
ATOM   11098 C  CG2 . THR B 1 550 ? 158.033 162.074 192.997 1.00 39.85  ? 550  THR B CG2 1 
ATOM   11099 N  N   . THR B 1 551 ? 154.644 163.666 196.128 1.00 39.20  ? 551  THR B N   1 
ATOM   11100 C  CA  . THR B 1 551 ? 153.256 164.049 196.366 1.00 39.20  ? 551  THR B CA  1 
ATOM   11101 C  C   . THR B 1 551 ? 153.042 165.545 196.163 1.00 39.20  ? 551  THR B C   1 
ATOM   11102 O  O   . THR B 1 551 ? 152.073 165.952 195.513 1.00 39.20  ? 551  THR B O   1 
ATOM   11103 C  CB  . THR B 1 551 ? 152.825 163.638 197.773 1.00 39.20  ? 551  THR B CB  1 
ATOM   11104 O  OG1 . THR B 1 551 ? 152.795 162.210 197.866 1.00 39.20  ? 551  THR B OG1 1 
ATOM   11105 C  CG2 . THR B 1 551 ? 151.442 164.181 198.085 1.00 39.20  ? 551  THR B CG2 1 
ATOM   11106 N  N   . ALA B 1 552 ? 153.922 166.377 196.718 1.00 39.36  ? 552  ALA B N   1 
ATOM   11107 C  CA  . ALA B 1 552 ? 153.751 167.823 196.587 1.00 39.36  ? 552  ALA B CA  1 
ATOM   11108 C  C   . ALA B 1 552 ? 153.858 168.310 195.146 1.00 39.36  ? 552  ALA B C   1 
ATOM   11109 O  O   . ALA B 1 552 ? 152.993 169.098 194.722 1.00 39.36  ? 552  ALA B O   1 
ATOM   11110 C  CB  . ALA B 1 552 ? 154.744 168.546 197.504 1.00 39.36  ? 552  ALA B CB  1 
ATOM   11111 N  N   . PRO B 1 553 ? 154.872 167.928 194.354 1.00 39.30  ? 553  PRO B N   1 
ATOM   11112 C  CA  . PRO B 1 553 ? 154.871 168.355 192.944 1.00 39.30  ? 553  PRO B CA  1 
ATOM   11113 C  C   . PRO B 1 553 ? 153.669 167.851 192.168 1.00 39.30  ? 553  PRO B C   1 
ATOM   11114 O  O   . PRO B 1 553 ? 153.144 168.570 191.308 1.00 39.30  ? 553  PRO B O   1 
ATOM   11115 C  CB  . PRO B 1 553 ? 156.185 167.775 192.402 1.00 39.30  ? 553  PRO B CB  1 
ATOM   11116 C  CG  . PRO B 1 553 ? 157.041 167.594 193.601 1.00 39.30  ? 553  PRO B CG  1 
ATOM   11117 C  CD  . PRO B 1 553 ? 156.099 167.179 194.683 1.00 39.30  ? 553  PRO B CD  1 
ATOM   11118 N  N   . ALA B 1 554 ? 153.212 166.629 192.451 1.00 39.48  ? 554  ALA B N   1 
ATOM   11119 C  CA  . ALA B 1 554 ? 152.036 166.105 191.764 1.00 39.48  ? 554  ALA B CA  1 
ATOM   11120 C  C   . ALA B 1 554 ? 150.788 166.903 192.119 1.00 39.48  ? 554  ALA B C   1 
ATOM   11121 O  O   . ALA B 1 554 ? 149.960 167.191 191.248 1.00 39.48  ? 554  ALA B O   1 
ATOM   11122 C  CB  . ALA B 1 554 ? 151.846 164.629 192.101 1.00 39.48  ? 554  ALA B CB  1 
ATOM   11123 N  N   . LEU B 1 555 ? 150.636 167.268 193.393 1.00 39.67  ? 555  LEU B N   1 
ATOM   11124 C  CA  . LEU B 1 555 ? 149.504 168.094 193.799 1.00 39.67  ? 555  LEU B CA  1 
ATOM   11125 C  C   . LEU B 1 555 ? 149.573 169.472 193.156 1.00 39.67  ? 555  LEU B C   1 
ATOM   11126 O  O   . LEU B 1 555 ? 148.545 170.024 192.745 1.00 39.67  ? 555  LEU B O   1 
ATOM   11127 C  CB  . LEU B 1 555 ? 149.461 168.214 195.322 1.00 39.67  ? 555  LEU B CB  1 
ATOM   11128 C  CG  . LEU B 1 555 ? 148.938 167.001 196.092 1.00 39.67  ? 555  LEU B CG  1 
ATOM   11129 C  CD1 . LEU B 1 555 ? 149.002 167.247 197.588 1.00 39.67  ? 555  LEU B CD1 1 
ATOM   11130 C  CD2 . LEU B 1 555 ? 147.521 166.672 195.666 1.00 39.67  ? 555  LEU B CD2 1 
ATOM   11131 N  N   . LYS B 1 556 ? 150.776 170.043 193.063 1.00 40.07  ? 556  LYS B N   1 
ATOM   11132 C  CA  . LYS B 1 556 ? 150.928 171.334 192.398 1.00 40.07  ? 556  LYS B CA  1 
ATOM   11133 C  C   . LYS B 1 556 ? 150.546 171.242 190.926 1.00 40.07  ? 556  LYS B C   1 
ATOM   11134 O  O   . LYS B 1 556 ? 149.860 172.125 190.399 1.00 40.07  ? 556  LYS B O   1 
ATOM   11135 C  CB  . LYS B 1 556 ? 152.362 171.838 192.551 1.00 40.07  ? 556  LYS B CB  1 
ATOM   11136 C  CG  . LYS B 1 556 ? 152.714 172.288 193.958 1.00 40.07  ? 556  LYS B CG  1 
ATOM   11137 C  CD  . LYS B 1 556 ? 154.175 172.692 194.055 1.00 40.07  ? 556  LYS B CD  1 
ATOM   11138 C  CE  . LYS B 1 556 ? 154.578 172.967 195.493 1.00 40.07  ? 556  LYS B CE  1 
ATOM   11139 N  NZ  . LYS B 1 556 ? 156.034 173.255 195.613 1.00 40.07  ? 556  LYS B NZ  1 
ATOM   11140 N  N   . ALA B 1 557 ? 150.978 170.176 190.249 1.00 40.66  ? 557  ALA B N   1 
ATOM   11141 C  CA  . ALA B 1 557 ? 150.621 169.991 188.845 1.00 40.66  ? 557  ALA B CA  1 
ATOM   11142 C  C   . ALA B 1 557 ? 149.116 169.809 188.681 1.00 40.66  ? 557  ALA B C   1 
ATOM   11143 O  O   . ALA B 1 557 ? 148.512 170.343 187.743 1.00 40.66  ? 557  ALA B O   1 
ATOM   11144 C  CB  . ALA B 1 557 ? 151.376 168.795 188.267 1.00 40.66  ? 557  ALA B CB  1 
ATOM   11145 N  N   . LEU B 1 558 ? 148.494 169.046 189.584 1.00 41.33  ? 558  LEU B N   1 
ATOM   11146 C  CA  . LEU B 1 558 ? 147.050 168.853 189.524 1.00 41.33  ? 558  LEU B CA  1 
ATOM   11147 C  C   . LEU B 1 558 ? 146.302 170.163 189.729 1.00 41.33  ? 558  LEU B C   1 
ATOM   11148 O  O   . LEU B 1 558 ? 145.314 170.428 189.036 1.00 41.33  ? 558  LEU B O   1 
ATOM   11149 C  CB  . LEU B 1 558 ? 146.613 167.824 190.567 1.00 41.33  ? 558  LEU B CB  1 
ATOM   11150 C  CG  . LEU B 1 558 ? 146.763 166.355 190.169 1.00 41.33  ? 558  LEU B CG  1 
ATOM   11151 C  CD1 . LEU B 1 558 ? 146.320 165.444 191.301 1.00 41.33  ? 558  LEU B CD1 1 
ATOM   11152 C  CD2 . LEU B 1 558 ? 145.973 166.065 188.906 1.00 41.33  ? 558  LEU B CD2 1 
ATOM   11153 N  N   . LYS B 1 559 ? 146.754 170.992 190.672 1.00 42.18  ? 559  LYS B N   1 
ATOM   11154 C  CA  . LYS B 1 559 ? 146.123 172.292 190.869 1.00 42.18  ? 559  LYS B CA  1 
ATOM   11155 C  C   . LYS B 1 559 ? 146.335 173.195 189.661 1.00 42.18  ? 559  LYS B C   1 
ATOM   11156 O  O   . LYS B 1 559 ? 145.451 173.983 189.305 1.00 42.18  ? 559  LYS B O   1 
ATOM   11157 C  CB  . LYS B 1 559 ? 146.658 172.955 192.136 1.00 42.18  ? 559  LYS B CB  1 
ATOM   11158 C  CG  . LYS B 1 559 ? 145.833 174.144 192.596 1.00 42.18  ? 559  LYS B CG  1 
ATOM   11159 C  CD  . LYS B 1 559 ? 144.373 173.762 192.783 1.00 42.18  ? 559  LYS B CD  1 
ATOM   11160 C  CE  . LYS B 1 559 ? 143.529 174.969 193.155 1.00 42.18  ? 559  LYS B CE  1 
ATOM   11161 N  NZ  . LYS B 1 559 ? 143.566 176.014 192.094 1.00 42.18  ? 559  LYS B NZ  1 
ATOM   11162 N  N   . ALA B 1 560 ? 147.505 173.101 189.024 1.00 42.00  ? 560  ALA B N   1 
ATOM   11163 C  CA  . ALA B 1 560 ? 147.751 173.867 187.807 1.00 42.00  ? 560  ALA B CA  1 
ATOM   11164 C  C   . ALA B 1 560 ? 146.796 173.446 186.697 1.00 42.00  ? 560  ALA B C   1 
ATOM   11165 O  O   . ALA B 1 560 ? 146.290 174.286 185.945 1.00 42.00  ? 560  ALA B O   1 
ATOM   11166 C  CB  . ALA B 1 560 ? 149.204 173.698 187.365 1.00 42.00  ? 560  ALA B CB  1 
ATOM   11167 N  N   . SER B 1 561 ? 146.547 172.141 186.575 1.00 42.92  ? 561  SER B N   1 
ATOM   11168 C  CA  . SER B 1 561 ? 145.569 171.661 185.604 1.00 42.92  ? 561  SER B CA  1 
ATOM   11169 C  C   . SER B 1 561 ? 144.175 172.177 185.936 1.00 42.92  ? 561  SER B C   1 
ATOM   11170 O  O   . SER B 1 561 ? 143.419 172.580 185.044 1.00 42.92  ? 561  SER B O   1 
ATOM   11171 C  CB  . SER B 1 561 ? 145.582 170.134 185.553 1.00 42.92  ? 561  SER B CB  1 
ATOM   11172 O  OG  . SER B 1 561 ? 146.880 169.642 185.269 1.00 42.92  ? 561  SER B OG  1 
ATOM   11173 N  N   . GLY B 1 562 ? 143.818 172.174 187.217 1.00 39.05  ? 562  GLY B N   1 
ATOM   11174 C  CA  . GLY B 1 562 ? 142.519 172.656 187.640 1.00 39.05  ? 562  GLY B CA  1 
ATOM   11175 C  C   . GLY B 1 562 ? 141.728 171.623 188.414 1.00 39.05  ? 562  GLY B C   1 
ATOM   11176 O  O   . GLY B 1 562 ? 140.535 171.808 188.670 1.00 39.05  ? 562  GLY B O   1 
ATOM   11177 N  N   . ILE B 1 563 ? 142.384 170.529 188.792 1.00 39.06  ? 563  ILE B N   1 
ATOM   11178 C  CA  . ILE B 1 563 ? 141.740 169.437 189.514 1.00 39.06  ? 563  ILE B CA  1 
ATOM   11179 C  C   . ILE B 1 563 ? 141.913 169.709 191.005 1.00 39.06  ? 563  ILE B C   1 
ATOM   11180 O  O   . ILE B 1 563 ? 142.990 169.505 191.567 1.00 39.06  ? 563  ILE B O   1 
ATOM   11181 C  CB  . ILE B 1 563 ? 142.316 168.077 189.116 1.00 39.06  ? 563  ILE B CB  1 
ATOM   11182 C  CG1 . ILE B 1 563 ? 142.285 167.910 187.596 1.00 39.06  ? 563  ILE B CG1 1 
ATOM   11183 C  CG2 . ILE B 1 563 ? 141.545 166.957 189.791 1.00 39.06  ? 563  ILE B CG2 1 
ATOM   11184 C  CD1 . ILE B 1 563 ? 142.675 166.527 187.123 1.00 39.06  ? 563  ILE B CD1 1 
ATOM   11185 N  N   . THR B 1 564 ? 140.844 170.171 191.648 1.00 39.97  ? 564  THR B N   1 
ATOM   11186 C  CA  . THR B 1 564 ? 140.869 170.426 193.085 1.00 39.97  ? 564  THR B CA  1 
ATOM   11187 C  C   . THR B 1 564 ? 140.878 169.097 193.830 1.00 39.97  ? 564  THR B C   1 
ATOM   11188 O  O   . THR B 1 564 ? 139.913 168.330 193.759 1.00 39.97  ? 564  THR B O   1 
ATOM   11189 C  CB  . THR B 1 564 ? 139.669 171.272 193.496 1.00 39.97  ? 564  THR B CB  1 
ATOM   11190 O  OG1 . THR B 1 564 ? 139.718 172.534 192.819 1.00 39.97  ? 564  THR B OG1 1 
ATOM   11191 C  CG2 . THR B 1 564 ? 139.675 171.508 194.997 1.00 39.97  ? 564  THR B CG2 1 
ATOM   11192 N  N   . VAL B 1 565 ? 141.963 168.824 194.545 1.00 37.93  ? 565  VAL B N   1 
ATOM   11193 C  CA  . VAL B 1 565 ? 142.133 167.561 195.252 1.00 37.93  ? 565  VAL B CA  1 
ATOM   11194 C  C   . VAL B 1 565 ? 141.490 167.669 196.628 1.00 37.93  ? 565  VAL B C   1 
ATOM   11195 O  O   . VAL B 1 565 ? 141.788 168.593 197.394 1.00 37.93  ? 565  VAL B O   1 
ATOM   11196 C  CB  . VAL B 1 565 ? 143.621 167.192 195.366 1.00 37.93  ? 565  VAL B CB  1 
ATOM   11197 C  CG1 . VAL B 1 565 ? 143.796 165.949 196.219 1.00 37.93  ? 565  VAL B CG1 1 
ATOM   11198 C  CG2 . VAL B 1 565 ? 144.218 166.986 193.985 1.00 37.93  ? 565  VAL B CG2 1 
ATOM   11199 N  N   . LYS B 1 566 ? 140.607 166.725 196.942 1.00 37.09  ? 566  LYS B N   1 
ATOM   11200 C  CA  . LYS B 1 566 ? 139.958 166.642 198.242 1.00 37.09  ? 566  LYS B CA  1 
ATOM   11201 C  C   . LYS B 1 566 ? 140.270 165.292 198.870 1.00 37.09  ? 566  LYS B C   1 
ATOM   11202 O  O   . LYS B 1 566 ? 140.383 164.283 198.168 1.00 37.09  ? 566  LYS B O   1 
ATOM   11203 C  CB  . LYS B 1 566 ? 138.444 166.830 198.120 1.00 37.09  ? 566  LYS B CB  1 
ATOM   11204 C  CG  . LYS B 1 566 ? 138.041 168.088 197.374 1.00 37.09  ? 566  LYS B CG  1 
ATOM   11205 C  CD  . LYS B 1 566 ? 136.613 168.485 197.697 1.00 37.09  ? 566  LYS B CD  1 
ATOM   11206 C  CE  . LYS B 1 566 ? 136.293 169.868 197.156 1.00 37.09  ? 566  LYS B CE  1 
ATOM   11207 N  NZ  . LYS B 1 566 ? 137.344 170.860 197.515 1.00 37.09  ? 566  LYS B NZ  1 
ATOM   11208 N  N   . ILE B 1 567 ? 140.410 165.276 200.192 1.00 36.99  ? 567  ILE B N   1 
ATOM   11209 C  CA  . ILE B 1 567 ? 140.805 164.081 200.927 1.00 36.99  ? 567  ILE B CA  1 
ATOM   11210 C  C   . ILE B 1 567 ? 139.598 163.589 201.713 1.00 36.99  ? 567  ILE B C   1 
ATOM   11211 O  O   . ILE B 1 567 ? 139.056 164.312 202.557 1.00 36.99  ? 567  ILE B O   1 
ATOM   11212 C  CB  . ILE B 1 567 ? 141.996 164.349 201.856 1.00 36.99  ? 567  ILE B CB  1 
ATOM   11213 C  CG1 . ILE B 1 567 ? 143.198 164.842 201.050 1.00 36.99  ? 567  ILE B CG1 1 
ATOM   11214 C  CG2 . ILE B 1 567 ? 142.357 163.095 202.631 1.00 36.99  ? 567  ILE B CG2 1 
ATOM   11215 C  CD1 . ILE B 1 567 ? 143.772 163.803 200.119 1.00 36.99  ? 567  ILE B CD1 1 
ATOM   11216 N  N   . LEU B 1 568 ? 139.177 162.359 201.436 1.00 38.84  ? 568  LEU B N   1 
ATOM   11217 C  CA  . LEU B 1 568 ? 138.136 161.680 202.199 1.00 38.84  ? 568  LEU B CA  1 
ATOM   11218 C  C   . LEU B 1 568 ? 138.777 160.479 202.883 1.00 38.84  ? 568  LEU B C   1 
ATOM   11219 O  O   . LEU B 1 568 ? 138.975 159.434 202.254 1.00 38.84  ? 568  LEU B O   1 
ATOM   11220 C  CB  . LEU B 1 568 ? 136.981 161.248 201.298 1.00 38.84  ? 568  LEU B CB  1 
ATOM   11221 C  CG  . LEU B 1 568 ? 136.343 162.324 200.422 1.00 38.84  ? 568  LEU B CG  1 
ATOM   11222 C  CD1 . LEU B 1 568 ? 135.318 161.705 199.489 1.00 38.84  ? 568  LEU B CD1 1 
ATOM   11223 C  CD2 . LEU B 1 568 ? 135.706 163.393 201.281 1.00 38.84  ? 568  LEU B CD2 1 
ATOM   11224 N  N   . THR B 1 569 ? 139.097 160.626 204.166 1.00 37.58  ? 569  THR B N   1 
ATOM   11225 C  CA  . THR B 1 569 ? 139.807 159.598 204.909 1.00 37.58  ? 569  THR B CA  1 
ATOM   11226 C  C   . THR B 1 569 ? 139.091 159.312 206.220 1.00 37.58  ? 569  THR B C   1 
ATOM   11227 O  O   . THR B 1 569 ? 138.472 160.197 206.817 1.00 37.58  ? 569  THR B O   1 
ATOM   11228 C  CB  . THR B 1 569 ? 141.259 160.009 205.191 1.00 37.58  ? 569  THR B CB  1 
ATOM   11229 O  OG1 . THR B 1 569 ? 141.894 159.007 205.995 1.00 37.58  ? 569  THR B OG1 1 
ATOM   11230 C  CG2 . THR B 1 569 ? 141.309 161.345 205.916 1.00 37.58  ? 569  THR B CG2 1 
ATOM   11231 N  N   . GLY B 1 570 ? 139.176 158.060 206.656 1.00 39.15  ? 570  GLY B N   1 
ATOM   11232 C  CA  . GLY B 1 570 ? 138.601 157.620 207.907 1.00 39.15  ? 570  GLY B CA  1 
ATOM   11233 C  C   . GLY B 1 570 ? 139.522 157.719 209.101 1.00 39.15  ? 570  GLY B C   1 
ATOM   11234 O  O   . GLY B 1 570 ? 139.153 157.271 210.192 1.00 39.15  ? 570  GLY B O   1 
ATOM   11235 N  N   . ASP B 1 571 ? 140.710 158.292 208.933 1.00 42.39  ? 571  ASP B N   1 
ATOM   11236 C  CA  . ASP B 1 571 ? 141.669 158.413 210.018 1.00 42.39  ? 571  ASP B CA  1 
ATOM   11237 C  C   . ASP B 1 571 ? 141.331 159.624 210.886 1.00 42.39  ? 571  ASP B C   1 
ATOM   11238 O  O   . ASP B 1 571 ? 140.363 160.348 210.643 1.00 42.39  ? 571  ASP B O   1 
ATOM   11239 C  CB  . ASP B 1 571 ? 143.088 158.512 209.461 1.00 42.39  ? 571  ASP B CB  1 
ATOM   11240 C  CG  . ASP B 1 571 ? 144.111 157.844 210.356 1.00 42.39  ? 571  ASP B CG  1 
ATOM   11241 O  OD1 . ASP B 1 571 ? 143.806 157.627 211.547 1.00 42.39  ? 571  ASP B OD1 1 
ATOM   11242 O  OD2 . ASP B 1 571 ? 145.219 157.538 209.870 1.00 42.39  ? 571  ASP B OD2 1 
ATOM   11243 N  N   . SER B 1 572 ? 142.140 159.843 211.918 1.00 45.64  ? 572  SER B N   1 
ATOM   11244 C  CA  . SER B 1 572 ? 141.938 160.981 212.803 1.00 45.64  ? 572  SER B CA  1 
ATOM   11245 C  C   . SER B 1 572 ? 142.210 162.287 212.067 1.00 45.64  ? 572  SER B C   1 
ATOM   11246 O  O   . SER B 1 572 ? 143.019 162.348 211.137 1.00 45.64  ? 572  SER B O   1 
ATOM   11247 C  CB  . SER B 1 572 ? 142.843 160.872 214.028 1.00 45.64  ? 572  SER B CB  1 
ATOM   11248 O  OG  . SER B 1 572 ? 142.712 162.011 214.861 1.00 45.64  ? 572  SER B OG  1 
ATOM   11249 N  N   . GLU B 1 573 ? 141.516 163.346 212.492 1.00 45.32  ? 573  GLU B N   1 
ATOM   11250 C  CA  . GLU B 1 573 ? 141.674 164.636 211.832 1.00 45.32  ? 573  GLU B CA  1 
ATOM   11251 C  C   . GLU B 1 573 ? 143.048 165.241 212.091 1.00 45.32  ? 573  GLU B C   1 
ATOM   11252 O  O   . GLU B 1 573 ? 143.554 165.996 211.255 1.00 45.32  ? 573  GLU B O   1 
ATOM   11253 C  CB  . GLU B 1 573 ? 140.569 165.598 212.273 1.00 45.32  ? 573  GLU B CB  1 
ATOM   11254 C  CG  . GLU B 1 573 ? 140.694 166.097 213.701 1.00 45.32  ? 573  GLU B CG  1 
ATOM   11255 C  CD  . GLU B 1 573 ? 140.000 165.189 214.696 1.00 45.32  ? 573  GLU B CD  1 
ATOM   11256 O  OE1 . GLU B 1 573 ? 139.710 164.028 214.340 1.00 45.32  ? 573  GLU B OE1 1 
ATOM   11257 O  OE2 . GLU B 1 573 ? 139.744 165.636 215.834 1.00 45.32  ? 573  GLU B OE2 1 
ATOM   11258 N  N   . LEU B 1 574 ? 143.668 164.920 213.227 1.00 44.21  ? 574  LEU B N   1 
ATOM   11259 C  CA  . LEU B 1 574 ? 144.995 165.454 213.518 1.00 44.21  ? 574  LEU B CA  1 
ATOM   11260 C  C   . LEU B 1 574 ? 146.038 164.883 212.565 1.00 44.21  ? 574  LEU B C   1 
ATOM   11261 O  O   . LEU B 1 574 ? 146.847 165.626 211.995 1.00 44.21  ? 574  LEU B O   1 
ATOM   11262 C  CB  . LEU B 1 574 ? 145.367 165.157 214.970 1.00 44.21  ? 574  LEU B CB  1 
ATOM   11263 C  CG  . LEU B 1 574 ? 144.414 165.712 216.030 1.00 44.21  ? 574  LEU B CG  1 
ATOM   11264 C  CD1 . LEU B 1 574 ? 144.436 164.845 217.277 1.00 44.21  ? 574  LEU B CD1 1 
ATOM   11265 C  CD2 . LEU B 1 574 ? 144.768 167.151 216.370 1.00 44.21  ? 574  LEU B CD2 1 
ATOM   11266 N  N   . VAL B 1 575 ? 146.027 163.562 212.373 1.00 43.96  ? 575  VAL B N   1 
ATOM   11267 C  CA  . VAL B 1 575 ? 146.988 162.930 211.474 1.00 43.96  ? 575  VAL B CA  1 
ATOM   11268 C  C   . VAL B 1 575 ? 146.762 163.390 210.041 1.00 43.96  ? 575  VAL B C   1 
ATOM   11269 O  O   . VAL B 1 575 ? 147.715 163.671 209.305 1.00 43.96  ? 575  VAL B O   1 
ATOM   11270 C  CB  . VAL B 1 575 ? 146.903 161.398 211.592 1.00 43.96  ? 575  VAL B CB  1 
ATOM   11271 C  CG1 . VAL B 1 575 ? 147.998 160.746 210.767 1.00 43.96  ? 575  VAL B CG1 1 
ATOM   11272 C  CG2 . VAL B 1 575 ? 146.996 160.974 213.046 1.00 43.96  ? 575  VAL B CG2 1 
ATOM   11273 N  N   . ALA B 1 576 ? 145.498 163.460 209.618 1.00 44.22  ? 576  ALA B N   1 
ATOM   11274 C  CA  . ALA B 1 576 ? 145.197 163.908 208.263 1.00 44.22  ? 576  ALA B CA  1 
ATOM   11275 C  C   . ALA B 1 576 ? 145.628 165.354 208.051 1.00 44.22  ? 576  ALA B C   1 
ATOM   11276 O  O   . ALA B 1 576 ? 146.177 165.697 206.998 1.00 44.22  ? 576  ALA B O   1 
ATOM   11277 C  CB  . ALA B 1 576 ? 143.706 163.742 207.976 1.00 44.22  ? 576  ALA B CB  1 
ATOM   11278 N  N   . ALA B 1 577 ? 145.388 166.217 209.041 1.00 43.17  ? 577  ALA B N   1 
ATOM   11279 C  CA  . ALA B 1 577 ? 145.814 167.608 208.932 1.00 43.17  ? 577  ALA B CA  1 
ATOM   11280 C  C   . ALA B 1 577 ? 147.330 167.718 208.860 1.00 43.17  ? 577  ALA B C   1 
ATOM   11281 O  O   . ALA B 1 577 ? 147.863 168.504 208.068 1.00 43.17  ? 577  ALA B O   1 
ATOM   11282 C  CB  . ALA B 1 577 ? 145.271 168.416 210.109 1.00 43.17  ? 577  ALA B CB  1 
ATOM   11283 N  N   . LYS B 1 578 ? 148.043 166.941 209.680 1.00 44.37  ? 578  LYS B N   1 
ATOM   11284 C  CA  . LYS B 1 578 ? 149.501 166.969 209.632 1.00 44.37  ? 578  LYS B CA  1 
ATOM   11285 C  C   . LYS B 1 578 ? 150.017 166.488 208.282 1.00 44.37  ? 578  LYS B C   1 
ATOM   11286 O  O   . LYS B 1 578 ? 150.952 167.071 207.724 1.00 44.37  ? 578  LYS B O   1 
ATOM   11287 C  CB  . LYS B 1 578 ? 150.083 166.121 210.762 1.00 44.37  ? 578  LYS B CB  1 
ATOM   11288 C  CG  . LYS B 1 578 ? 151.578 165.877 210.642 1.00 44.37  ? 578  LYS B CG  1 
ATOM   11289 C  CD  . LYS B 1 578 ? 152.363 167.177 210.732 1.00 44.37  ? 578  LYS B CD  1 
ATOM   11290 C  CE  . LYS B 1 578 ? 153.834 166.913 211.011 1.00 44.37  ? 578  LYS B CE  1 
ATOM   11291 N  NZ  . LYS B 1 578 ? 154.513 168.104 211.592 1.00 44.37  ? 578  LYS B NZ  1 
ATOM   11292 N  N   . VAL B 1 579 ? 149.416 165.427 207.740 1.00 44.12  ? 579  VAL B N   1 
ATOM   11293 C  CA  . VAL B 1 579 ? 149.833 164.922 206.434 1.00 44.12  ? 579  VAL B CA  1 
ATOM   11294 C  C   . VAL B 1 579 ? 149.578 165.964 205.352 1.00 44.12  ? 579  VAL B C   1 
ATOM   11295 O  O   . VAL B 1 579 ? 150.427 166.200 204.482 1.00 44.12  ? 579  VAL B O   1 
ATOM   11296 C  CB  . VAL B 1 579 ? 149.118 163.593 206.126 1.00 44.12  ? 579  VAL B CB  1 
ATOM   11297 C  CG1 . VAL B 1 579 ? 149.122 163.316 204.633 1.00 44.12  ? 579  VAL B CG1 1 
ATOM   11298 C  CG2 . VAL B 1 579 ? 149.776 162.453 206.884 1.00 44.12  ? 579  VAL B CG2 1 
ATOM   11299 N  N   . CYS B 1 580 ? 148.408 166.608 205.391 1.00 47.58  ? 580  CYS B N   1 
ATOM   11300 C  CA  . CYS B 1 580 ? 148.088 167.629 204.399 1.00 47.58  ? 580  CYS B CA  1 
ATOM   11301 C  C   . CYS B 1 580 ? 149.049 168.808 204.490 1.00 47.58  ? 580  CYS B C   1 
ATOM   11302 O  O   . CYS B 1 580 ? 149.473 169.353 203.464 1.00 47.58  ? 580  CYS B O   1 
ATOM   11303 C  CB  . CYS B 1 580 ? 146.644 168.097 204.577 1.00 47.58  ? 580  CYS B CB  1 
ATOM   11304 S  SG  . CYS B 1 580 ? 145.407 166.941 203.947 1.00 47.58  ? 580  CYS B SG  1 
ATOM   11305 N  N   . HIS B 1 581 ? 149.396 169.223 205.710 1.00 50.89  ? 581  HIS B N   1 
ATOM   11306 C  CA  . HIS B 1 581 ? 150.368 170.299 205.871 1.00 50.89  ? 581  HIS B CA  1 
ATOM   11307 C  C   . HIS B 1 581 ? 151.744 169.881 205.368 1.00 50.89  ? 581  HIS B C   1 
ATOM   11308 O  O   . HIS B 1 581 ? 152.470 170.692 204.781 1.00 50.89  ? 581  HIS B O   1 
ATOM   11309 C  CB  . HIS B 1 581 ? 150.437 170.727 207.336 1.00 50.89  ? 581  HIS B CB  1 
ATOM   11310 C  CG  . HIS B 1 581 ? 151.563 171.665 207.638 1.00 50.89  ? 581  HIS B CG  1 
ATOM   11311 N  ND1 . HIS B 1 581 ? 152.741 171.250 208.219 1.00 50.89  ? 581  HIS B ND1 1 
ATOM   11312 C  CD2 . HIS B 1 581 ? 151.692 172.998 207.438 1.00 50.89  ? 581  HIS B CD2 1 
ATOM   11313 C  CE1 . HIS B 1 581 ? 153.547 172.286 208.365 1.00 50.89  ? 581  HIS B CE1 1 
ATOM   11314 N  NE2 . HIS B 1 581 ? 152.934 173.359 207.899 1.00 50.89  ? 581  HIS B NE2 1 
ATOM   11315 N  N   . GLU B 1 582 ? 152.123 168.621 205.597 1.00 48.55  ? 582  GLU B N   1 
ATOM   11316 C  CA  . GLU B 1 582 ? 153.409 168.130 205.113 1.00 48.55  ? 582  GLU B CA  1 
ATOM   11317 C  C   . GLU B 1 582 ? 153.467 168.134 203.591 1.00 48.55  ? 582  GLU B C   1 
ATOM   11318 O  O   . GLU B 1 582 ? 154.481 168.527 203.002 1.00 48.55  ? 582  GLU B O   1 
ATOM   11319 C  CB  . GLU B 1 582 ? 153.667 166.724 205.653 1.00 48.55  ? 582  GLU B CB  1 
ATOM   11320 C  CG  . GLU B 1 582 ? 154.192 166.692 207.077 1.00 48.55  ? 582  GLU B CG  1 
ATOM   11321 C  CD  . GLU B 1 582 ? 155.623 167.179 207.179 1.00 48.55  ? 582  GLU B CD  1 
ATOM   11322 O  OE1 . GLU B 1 582 ? 156.411 166.905 206.250 1.00 48.55  ? 582  GLU B OE1 1 
ATOM   11323 O  OE2 . GLU B 1 582 ? 155.959 167.834 208.188 1.00 48.55  ? 582  GLU B OE2 1 
ATOM   11324 N  N   . VAL B 1 583 ? 152.386 167.699 202.933 1.00 45.01  ? 583  VAL B N   1 
ATOM   11325 C  CA  . VAL B 1 583 ? 152.373 167.617 201.476 1.00 45.01  ? 583  VAL B CA  1 
ATOM   11326 C  C   . VAL B 1 583 ? 152.044 168.948 200.817 1.00 45.01  ? 583  VAL B C   1 
ATOM   11327 O  O   . VAL B 1 583 ? 152.031 169.029 199.581 1.00 45.01  ? 583  VAL B O   1 
ATOM   11328 C  CB  . VAL B 1 583 ? 151.376 166.546 200.987 1.00 45.01  ? 583  VAL B CB  1 
ATOM   11329 C  CG1 . VAL B 1 583 ? 151.729 165.189 201.575 1.00 45.01  ? 583  VAL B CG1 1 
ATOM   11330 C  CG2 . VAL B 1 583 ? 149.953 166.941 201.336 1.00 45.01  ? 583  VAL B CG2 1 
ATOM   11331 N  N   . GLY B 1 584 ? 151.780 169.993 201.598 1.00 45.47  ? 584  GLY B N   1 
ATOM   11332 C  CA  . GLY B 1 584 ? 151.509 171.310 201.068 1.00 45.47  ? 584  GLY B CA  1 
ATOM   11333 C  C   . GLY B 1 584 ? 150.048 171.617 200.821 1.00 45.47  ? 584  GLY B C   1 
ATOM   11334 O  O   . GLY B 1 584 ? 149.722 172.765 200.496 1.00 45.47  ? 584  GLY B O   1 
ATOM   11335 N  N   . LEU B 1 585 ? 149.163 170.634 200.958 1.00 46.61  ? 585  LEU B N   1 
ATOM   11336 C  CA  . LEU B 1 585 ? 147.741 170.879 200.768 1.00 46.61  ? 585  LEU B CA  1 
ATOM   11337 C  C   . LEU B 1 585 ? 147.199 171.763 201.885 1.00 46.61  ? 585  LEU B C   1 
ATOM   11338 O  O   . LEU B 1 585 ? 147.635 171.677 203.036 1.00 46.61  ? 585  LEU B O   1 
ATOM   11339 C  CB  . LEU B 1 585 ? 146.975 169.558 200.724 1.00 46.61  ? 585  LEU B CB  1 
ATOM   11340 C  CG  . LEU B 1 585 ? 145.642 169.576 199.977 1.00 46.61  ? 585  LEU B CG  1 
ATOM   11341 C  CD1 . LEU B 1 585 ? 145.847 170.014 198.538 1.00 46.61  ? 585  LEU B CD1 1 
ATOM   11342 C  CD2 . LEU B 1 585 ? 144.970 168.214 200.035 1.00 46.61  ? 585  LEU B CD2 1 
ATOM   11343 N  N   . ASP B 1 586 ? 146.242 172.621 201.539 1.00 54.00  ? 586  ASP B N   1 
ATOM   11344 C  CA  . ASP B 1 586 ? 145.624 173.527 202.501 1.00 54.00  ? 586  ASP B CA  1 
ATOM   11345 C  C   . ASP B 1 586 ? 144.433 172.824 203.142 1.00 54.00  ? 586  ASP B C   1 
ATOM   11346 O  O   . ASP B 1 586 ? 143.373 172.692 202.521 1.00 54.00  ? 586  ASP B O   1 
ATOM   11347 C  CB  . ASP B 1 586 ? 145.196 174.827 201.826 1.00 54.00  ? 586  ASP B CB  1 
ATOM   11348 C  CG  . ASP B 1 586 ? 145.148 175.994 202.792 1.00 54.00  ? 586  ASP B CG  1 
ATOM   11349 O  OD1 . ASP B 1 586 ? 145.630 175.840 203.934 1.00 54.00  ? 586  ASP B OD1 1 
ATOM   11350 O  OD2 . ASP B 1 586 ? 144.627 177.063 202.412 1.00 54.00  ? 586  ASP B OD2 1 
ATOM   11351 N  N   . ALA B 1 587 ? 144.608 172.376 204.387 1.00 51.32  ? 587  ALA B N   1 
ATOM   11352 C  CA  . ALA B 1 587 ? 143.526 171.690 205.083 1.00 51.32  ? 587  ALA B CA  1 
ATOM   11353 C  C   . ALA B 1 587 ? 142.365 172.627 205.389 1.00 51.32  ? 587  ALA B C   1 
ATOM   11354 O  O   . ALA B 1 587 ? 141.204 172.207 205.338 1.00 51.32  ? 587  ALA B O   1 
ATOM   11355 C  CB  . ALA B 1 587 ? 144.049 171.056 206.371 1.00 51.32  ? 587  ALA B CB  1 
ATOM   11356 N  N   . GLY B 1 588 ? 142.652 173.890 205.694 1.00 52.22  ? 588  GLY B N   1 
ATOM   11357 C  CA  . GLY B 1 588 ? 141.589 174.806 206.071 1.00 52.22  ? 588  GLY B CA  1 
ATOM   11358 C  C   . GLY B 1 588 ? 140.910 174.351 207.345 1.00 52.22  ? 588  GLY B C   1 
ATOM   11359 O  O   . GLY B 1 588 ? 141.556 174.091 208.367 1.00 52.22  ? 588  GLY B O   1 
ATOM   11360 N  N   . GLU B 1 589 ? 139.586 174.250 207.290 1.00 52.83  ? 589  GLU B N   1 
ATOM   11361 C  CA  . GLU B 1 589 ? 138.794 173.730 208.396 1.00 52.83  ? 589  GLU B CA  1 
ATOM   11362 C  C   . GLU B 1 589 ? 138.366 172.304 208.076 1.00 52.83  ? 589  GLU B C   1 
ATOM   11363 O  O   . GLU B 1 589 ? 137.897 172.022 206.968 1.00 52.83  ? 589  GLU B O   1 
ATOM   11364 C  CB  . GLU B 1 589 ? 137.583 174.628 208.672 1.00 52.83  ? 589  GLU B CB  1 
ATOM   11365 C  CG  . GLU B 1 589 ? 136.622 174.823 207.503 1.00 52.83  ? 589  GLU B CG  1 
ATOM   11366 C  CD  . GLU B 1 589 ? 135.536 173.766 207.449 1.00 52.83  ? 589  GLU B CD  1 
ATOM   11367 O  OE1 . GLU B 1 589 ? 135.291 173.112 208.484 1.00 52.83  ? 589  GLU B OE1 1 
ATOM   11368 O  OE2 . GLU B 1 589 ? 134.927 173.590 206.373 1.00 52.83  ? 589  GLU B OE2 1 
ATOM   11369 N  N   . VAL B 1 590 ? 138.559 171.406 209.031 1.00 48.80  ? 590  VAL B N   1 
ATOM   11370 C  CA  . VAL B 1 590 ? 138.269 169.991 208.837 1.00 48.80  ? 590  VAL B CA  1 
ATOM   11371 C  C   . VAL B 1 590 ? 136.820 169.718 209.211 1.00 48.80  ? 590  VAL B C   1 
ATOM   11372 O  O   . VAL B 1 590 ? 136.232 170.386 210.067 1.00 48.80  ? 590  VAL B O   1 
ATOM   11373 C  CB  . VAL B 1 590 ? 139.242 169.110 209.649 1.00 48.80  ? 590  VAL B CB  1 
ATOM   11374 C  CG1 . VAL B 1 590 ? 140.679 169.517 209.369 1.00 48.80  ? 590  VAL B CG1 1 
ATOM   11375 C  CG2 . VAL B 1 590 ? 138.942 169.205 211.136 1.00 48.80  ? 590  VAL B CG2 1 
ATOM   11376 N  N   . VAL B 1 591 ? 136.231 168.730 208.542 1.00 48.37  ? 591  VAL B N   1 
ATOM   11377 C  CA  . VAL B 1 591 ? 134.866 168.289 208.805 1.00 48.37  ? 591  VAL B CA  1 
ATOM   11378 C  C   . VAL B 1 591 ? 134.911 166.803 209.123 1.00 48.37  ? 591  VAL B C   1 
ATOM   11379 O  O   . VAL B 1 591 ? 135.399 166.005 208.313 1.00 48.37  ? 591  VAL B O   1 
ATOM   11380 C  CB  . VAL B 1 591 ? 133.933 168.567 207.617 1.00 48.37  ? 591  VAL B CB  1 
ATOM   11381 C  CG1 . VAL B 1 591 ? 132.511 168.170 207.962 1.00 48.37  ? 591  VAL B CG1 1 
ATOM   11382 C  CG2 . VAL B 1 591 ? 133.992 170.034 207.228 1.00 48.37  ? 591  VAL B CG2 1 
ATOM   11383 N  N   . ILE B 1 592 ? 134.409 166.433 210.295 1.00 54.02  ? 592  ILE B N   1 
ATOM   11384 C  CA  . ILE B 1 592 ? 134.371 165.037 210.700 1.00 54.02  ? 592  ILE B CA  1 
ATOM   11385 C  C   . ILE B 1 592 ? 133.047 164.425 210.261 1.00 54.02  ? 592  ILE B C   1 
ATOM   11386 O  O   . ILE B 1 592 ? 132.082 165.125 209.942 1.00 54.02  ? 592  ILE B O   1 
ATOM   11387 C  CB  . ILE B 1 592 ? 134.585 164.878 212.219 1.00 54.02  ? 592  ILE B CB  1 
ATOM   11388 C  CG1 . ILE B 1 592 ? 133.371 165.391 212.992 1.00 54.02  ? 592  ILE B CG1 1 
ATOM   11389 C  CG2 . ILE B 1 592 ? 135.844 165.607 212.657 1.00 54.02  ? 592  ILE B CG2 1 
ATOM   11390 C  CD1 . ILE B 1 592 ? 133.244 164.807 214.382 1.00 54.02  ? 592  ILE B CD1 1 
ATOM   11391 N  N   . GLY B 1 593 ? 133.007 163.091 210.234 1.00 58.45  ? 593  GLY B N   1 
ATOM   11392 C  CA  . GLY B 1 593 ? 131.803 162.402 209.800 1.00 58.45  ? 593  GLY B CA  1 
ATOM   11393 C  C   . GLY B 1 593 ? 130.608 162.658 210.696 1.00 58.45  ? 593  GLY B C   1 
ATOM   11394 O  O   . GLY B 1 593 ? 129.491 162.855 210.208 1.00 58.45  ? 593  GLY B O   1 
ATOM   11395 N  N   . SER B 1 594 ? 130.824 162.692 212.011 1.00 61.57  ? 594  SER B N   1 
ATOM   11396 C  CA  . SER B 1 594 ? 129.720 162.901 212.939 1.00 61.57  ? 594  SER B CA  1 
ATOM   11397 C  C   . SER B 1 594 ? 129.058 164.259 212.752 1.00 61.57  ? 594  SER B C   1 
ATOM   11398 O  O   . SER B 1 594 ? 127.954 164.473 213.263 1.00 61.57  ? 594  SER B O   1 
ATOM   11399 C  CB  . SER B 1 594 ? 130.209 162.751 214.380 1.00 61.57  ? 594  SER B CB  1 
ATOM   11400 O  OG  . SER B 1 594 ? 129.218 163.173 215.301 1.00 61.57  ? 594  SER B OG  1 
ATOM   11401 N  N   . ASP B 1 595 ? 129.706 165.178 212.038 1.00 62.95  ? 595  ASP B N   1 
ATOM   11402 C  CA  . ASP B 1 595 ? 129.158 166.500 211.778 1.00 62.95  ? 595  ASP B CA  1 
ATOM   11403 C  C   . ASP B 1 595 ? 128.472 166.607 210.421 1.00 62.95  ? 595  ASP B C   1 
ATOM   11404 O  O   . ASP B 1 595 ? 128.073 167.708 210.032 1.00 62.95  ? 595  ASP B O   1 
ATOM   11405 C  CB  . ASP B 1 595 ? 130.260 167.556 211.886 1.00 62.95  ? 595  ASP B CB  1 
ATOM   11406 C  CG  . ASP B 1 595 ? 130.803 167.687 213.294 1.00 62.95  ? 595  ASP B CG  1 
ATOM   11407 O  OD1 . ASP B 1 595 ? 130.319 166.962 214.188 1.00 62.95  ? 595  ASP B OD1 1 
ATOM   11408 O  OD2 . ASP B 1 595 ? 131.714 168.515 213.507 1.00 62.95  ? 595  ASP B OD2 1 
ATOM   11409 N  N   . ILE B 1 596 ? 128.326 165.503 209.688 1.00 62.52  ? 596  ILE B N   1 
ATOM   11410 C  CA  . ILE B 1 596 ? 127.595 165.536 208.427 1.00 62.52  ? 596  ILE B CA  1 
ATOM   11411 C  C   . ILE B 1 596 ? 126.302 164.731 208.473 1.00 62.52  ? 596  ILE B C   1 
ATOM   11412 O  O   . ILE B 1 596 ? 125.461 164.898 207.577 1.00 62.52  ? 596  ILE B O   1 
ATOM   11413 C  CB  . ILE B 1 596 ? 128.467 165.068 207.243 1.00 62.52  ? 596  ILE B CB  1 
ATOM   11414 C  CG1 . ILE B 1 596 ? 128.760 163.571 207.335 1.00 62.52  ? 596  ILE B CG1 1 
ATOM   11415 C  CG2 . ILE B 1 596 ? 129.760 165.860 207.188 1.00 62.52  ? 596  ILE B CG2 1 
ATOM   11416 C  CD1 . ILE B 1 596 ? 129.395 163.003 206.089 1.00 62.52  ? 596  ILE B CD1 1 
ATOM   11417 N  N   . GLU B 1 597 ? 126.116 163.864 209.471 1.00 69.61  ? 597  GLU B N   1 
ATOM   11418 C  CA  . GLU B 1 597 ? 124.856 163.139 209.593 1.00 69.61  ? 597  GLU B CA  1 
ATOM   11419 C  C   . GLU B 1 597 ? 123.700 164.094 209.865 1.00 69.61  ? 597  GLU B C   1 
ATOM   11420 O  O   . GLU B 1 597 ? 122.616 163.959 209.288 1.00 69.61  ? 597  GLU B O   1 
ATOM   11421 C  CB  . GLU B 1 597 ? 124.959 162.086 210.696 1.00 69.61  ? 597  GLU B CB  1 
ATOM   11422 C  CG  . GLU B 1 597 ? 125.911 160.947 210.379 1.00 69.61  ? 597  GLU B CG  1 
ATOM   11423 C  CD  . GLU B 1 597 ? 125.928 159.885 211.460 1.00 69.61  ? 597  GLU B CD  1 
ATOM   11424 O  OE1 . GLU B 1 597 ? 125.215 160.054 212.471 1.00 69.61  ? 597  GLU B OE1 1 
ATOM   11425 O  OE2 . GLU B 1 597 ? 126.653 158.881 211.299 1.00 69.61  ? 597  GLU B OE2 1 
ATOM   11426 N  N   . THR B 1 598 ? 123.917 165.069 210.751 1.00 72.00  ? 598  THR B N   1 
ATOM   11427 C  CA  . THR B 1 598 ? 122.872 166.044 211.048 1.00 72.00  ? 598  THR B CA  1 
ATOM   11428 C  C   . THR B 1 598 ? 122.633 166.978 209.869 1.00 72.00  ? 598  THR B C   1 
ATOM   11429 O  O   . THR B 1 598 ? 121.498 167.405 209.629 1.00 72.00  ? 598  THR B O   1 
ATOM   11430 C  CB  . THR B 1 598 ? 123.241 166.845 212.297 1.00 72.00  ? 598  THR B CB  1 
ATOM   11431 O  OG1 . THR B 1 598 ? 124.156 167.889 211.943 1.00 72.00  ? 598  THR B OG1 1 
ATOM   11432 C  CG2 . THR B 1 598 ? 123.886 165.942 213.336 1.00 72.00  ? 598  THR B CG2 1 
ATOM   11433 N  N   . LEU B 1 599 ? 123.688 167.310 209.128 1.00 69.53  ? 599  LEU B N   1 
ATOM   11434 C  CA  . LEU B 1 599 ? 123.558 168.223 208.002 1.00 69.53  ? 599  LEU B CA  1 
ATOM   11435 C  C   . LEU B 1 599 ? 122.695 167.614 206.904 1.00 69.53  ? 599  LEU B C   1 
ATOM   11436 O  O   . LEU B 1 599 ? 122.788 166.420 206.605 1.00 69.53  ? 599  LEU B O   1 
ATOM   11437 C  CB  . LEU B 1 599 ? 124.938 168.577 207.447 1.00 69.53  ? 599  LEU B CB  1 
ATOM   11438 C  CG  . LEU B 1 599 ? 125.817 169.477 208.315 1.00 69.53  ? 599  LEU B CG  1 
ATOM   11439 C  CD1 . LEU B 1 599 ? 127.128 169.775 207.608 1.00 69.53  ? 599  LEU B CD1 1 
ATOM   11440 C  CD2 . LEU B 1 599 ? 125.087 170.765 208.657 1.00 69.53  ? 599  LEU B CD2 1 
ATOM   11441 N  N   . SER B 1 600 ? 121.851 168.447 206.304 1.00 70.66  ? 600  SER B N   1 
ATOM   11442 C  CA  . SER B 1 600 ? 121.013 168.016 205.197 1.00 70.66  ? 600  SER B CA  1 
ATOM   11443 C  C   . SER B 1 600 ? 121.835 167.904 203.919 1.00 70.66  ? 600  SER B C   1 
ATOM   11444 O  O   . SER B 1 600 ? 123.028 168.220 203.893 1.00 70.66  ? 600  SER B O   1 
ATOM   11445 C  CB  . SER B 1 600 ? 119.855 168.992 204.988 1.00 70.66  ? 600  SER B CB  1 
ATOM   11446 O  OG  . SER B 1 600 ? 120.328 170.262 204.574 1.00 70.66  ? 600  SER B OG  1 
ATOM   11447 N  N   . ASP B 1 601 ? 121.182 167.441 202.851 1.00 69.37  ? 601  ASP B N   1 
ATOM   11448 C  CA  . ASP B 1 601 ? 121.855 167.282 201.567 1.00 69.37  ? 601  ASP B CA  1 
ATOM   11449 C  C   . ASP B 1 601 ? 122.369 168.616 201.037 1.00 69.37  ? 601  ASP B C   1 
ATOM   11450 O  O   . ASP B 1 601 ? 123.511 168.721 200.576 1.00 69.37  ? 601  ASP B O   1 
ATOM   11451 C  CB  . ASP B 1 601 ? 120.903 166.632 200.558 1.00 69.37  ? 601  ASP B CB  1 
ATOM   11452 C  CG  . ASP B 1 601 ? 120.523 165.217 200.943 1.00 69.37  ? 601  ASP B CG  1 
ATOM   11453 O  OD1 . ASP B 1 601 ? 120.973 164.748 202.010 1.00 69.37  ? 601  ASP B OD1 1 
ATOM   11454 O  OD2 . ASP B 1 601 ? 119.777 164.572 200.177 1.00 69.37  ? 601  ASP B OD2 1 
ATOM   11455 N  N   . ASP B 1 602 ? 121.528 169.651 201.100 1.00 71.88  ? 602  ASP B N   1 
ATOM   11456 C  CA  . ASP B 1 602 ? 121.928 170.968 200.614 1.00 71.88  ? 602  ASP B CA  1 
ATOM   11457 C  C   . ASP B 1 602 ? 123.084 171.531 201.431 1.00 71.88  ? 602  ASP B C   1 
ATOM   11458 O  O   . ASP B 1 602 ? 124.031 172.102 200.879 1.00 71.88  ? 602  ASP B O   1 
ATOM   11459 C  CB  . ASP B 1 602 ? 120.733 171.922 200.643 1.00 71.88  ? 602  ASP B CB  1 
ATOM   11460 C  CG  . ASP B 1 602 ? 119.745 171.651 199.527 1.00 71.88  ? 602  ASP B CG  1 
ATOM   11461 O  OD1 . ASP B 1 602 ? 120.155 171.684 198.347 1.00 71.88  ? 602  ASP B OD1 1 
ATOM   11462 O  OD2 . ASP B 1 602 ? 118.558 171.408 199.830 1.00 71.88  ? 602  ASP B OD2 1 
ATOM   11463 N  N   . GLU B 1 603 ? 123.019 171.382 202.756 1.00 71.22  ? 603  GLU B N   1 
ATOM   11464 C  CA  . GLU B 1 603 ? 124.079 171.900 203.614 1.00 71.22  ? 603  GLU B CA  1 
ATOM   11465 C  C   . GLU B 1 603 ? 125.405 171.202 203.335 1.00 71.22  ? 603  GLU B C   1 
ATOM   11466 O  O   . GLU B 1 603 ? 126.454 171.850 203.231 1.00 71.22  ? 603  GLU B O   1 
ATOM   11467 C  CB  . GLU B 1 603 ? 123.684 171.739 205.083 1.00 71.22  ? 603  GLU B CB  1 
ATOM   11468 C  CG  . GLU B 1 603 ? 122.520 172.616 205.509 1.00 71.22  ? 603  GLU B CG  1 
ATOM   11469 C  CD  . GLU B 1 603 ? 121.970 172.234 206.867 1.00 71.22  ? 603  GLU B CD  1 
ATOM   11470 O  OE1 . GLU B 1 603 ? 121.470 171.098 207.010 1.00 71.22  ? 603  GLU B OE1 1 
ATOM   11471 O  OE2 . GLU B 1 603 ? 122.038 173.069 207.792 1.00 71.22  ? 603  GLU B OE2 1 
ATOM   11472 N  N   . LEU B 1 604 ? 125.375 169.873 203.209 1.00 66.55  ? 604  LEU B N   1 
ATOM   11473 C  CA  . LEU B 1 604 ? 126.601 169.133 202.931 1.00 66.55  ? 604  LEU B CA  1 
ATOM   11474 C  C   . LEU B 1 604 ? 127.153 169.479 201.554 1.00 66.55  ? 604  LEU B C   1 
ATOM   11475 O  O   . LEU B 1 604 ? 128.370 169.617 201.383 1.00 66.55  ? 604  LEU B O   1 
ATOM   11476 C  CB  . LEU B 1 604 ? 126.350 167.630 203.051 1.00 66.55  ? 604  LEU B CB  1 
ATOM   11477 C  CG  . LEU B 1 604 ? 127.565 166.735 202.801 1.00 66.55  ? 604  LEU B CG  1 
ATOM   11478 C  CD1 . LEU B 1 604 ? 128.740 167.181 203.656 1.00 66.55  ? 604  LEU B CD1 1 
ATOM   11479 C  CD2 . LEU B 1 604 ? 127.228 165.280 203.076 1.00 66.55  ? 604  LEU B CD2 1 
ATOM   11480 N  N   . ALA B 1 605 ? 126.274 169.622 200.559 1.00 66.55  ? 605  ALA B N   1 
ATOM   11481 C  CA  . ALA B 1 605 ? 126.711 170.027 199.229 1.00 66.55  ? 605  ALA B CA  1 
ATOM   11482 C  C   . ALA B 1 605 ? 127.292 171.433 199.208 1.00 66.55  ? 605  ALA B C   1 
ATOM   11483 O  O   . ALA B 1 605 ? 128.202 171.696 198.415 1.00 66.55  ? 605  ALA B O   1 
ATOM   11484 C  CB  . ALA B 1 605 ? 125.548 169.934 198.241 1.00 66.55  ? 605  ALA B CB  1 
ATOM   11485 N  N   . ASN B 1 606 ? 126.791 172.336 200.050 1.00 70.59  ? 606  ASN B N   1 
ATOM   11486 C  CA  . ASN B 1 606 ? 127.350 173.675 200.156 1.00 70.59  ? 606  ASN B CA  1 
ATOM   11487 C  C   . ASN B 1 606 ? 128.655 173.716 200.937 1.00 70.59  ? 606  ASN B C   1 
ATOM   11488 O  O   . ASN B 1 606 ? 129.486 174.593 200.679 1.00 70.59  ? 606  ASN B O   1 
ATOM   11489 C  CB  . ASN B 1 606 ? 126.340 174.621 200.818 1.00 70.59  ? 606  ASN B CB  1 
ATOM   11490 C  CG  . ASN B 1 606 ? 126.583 176.073 200.462 1.00 70.59  ? 606  ASN B CG  1 
ATOM   11491 O  OD1 . ASN B 1 606 ? 126.821 176.907 201.335 1.00 70.59  ? 606  ASN B OD1 1 
ATOM   11492 N  ND2 . ASN B 1 606 ? 126.521 176.384 199.172 1.00 70.59  ? 606  ASN B ND2 1 
ATOM   11493 N  N   . LEU B 1 607 ? 128.853 172.793 201.877 1.00 67.33  ? 607  LEU B N   1 
ATOM   11494 C  CA  . LEU B 1 607 ? 130.093 172.719 202.639 1.00 67.33  ? 607  LEU B CA  1 
ATOM   11495 C  C   . LEU B 1 607 ? 131.183 171.928 201.932 1.00 67.33  ? 607  LEU B C   1 
ATOM   11496 O  O   . LEU B 1 607 ? 132.368 172.198 202.151 1.00 67.33  ? 607  LEU B O   1 
ATOM   11497 C  CB  . LEU B 1 607 ? 129.834 172.095 204.015 1.00 67.33  ? 607  LEU B CB  1 
ATOM   11498 C  CG  . LEU B 1 607 ? 129.074 172.960 205.023 1.00 67.33  ? 607  LEU B CG  1 
ATOM   11499 C  CD1 . LEU B 1 607 ? 129.361 172.504 206.444 1.00 67.33  ? 607  LEU B CD1 1 
ATOM   11500 C  CD2 . LEU B 1 607 ? 129.422 174.432 204.851 1.00 67.33  ? 607  LEU B CD2 1 
ATOM   11501 N  N   . ALA B 1 608 ? 130.812 170.962 201.090 1.00 60.75  ? 608  ALA B N   1 
ATOM   11502 C  CA  . ALA B 1 608 ? 131.796 170.175 200.358 1.00 60.75  ? 608  ALA B CA  1 
ATOM   11503 C  C   . ALA B 1 608 ? 132.482 170.964 199.253 1.00 60.75  ? 608  ALA B C   1 
ATOM   11504 O  O   . ALA B 1 608 ? 133.510 170.510 198.740 1.00 60.75  ? 608  ALA B O   1 
ATOM   11505 C  CB  . ALA B 1 608 ? 131.136 168.928 199.767 1.00 60.75  ? 608  ALA B CB  1 
ATOM   11506 N  N   . GLN B 1 609 ? 131.948 172.123 198.875 1.00 64.23  ? 609  GLN B N   1 
ATOM   11507 C  CA  . GLN B 1 609 ? 132.561 172.958 197.853 1.00 64.23  ? 609  GLN B CA  1 
ATOM   11508 C  C   . GLN B 1 609 ? 133.602 173.916 198.414 1.00 64.23  ? 609  GLN B C   1 
ATOM   11509 O  O   . GLN B 1 609 ? 134.206 174.670 197.643 1.00 64.23  ? 609  GLN B O   1 
ATOM   11510 C  CB  . GLN B 1 609 ? 131.486 173.756 197.106 1.00 64.23  ? 609  GLN B CB  1 
ATOM   11511 C  CG  . GLN B 1 609 ? 130.454 172.898 196.387 1.00 64.23  ? 609  GLN B CG  1 
ATOM   11512 C  CD  . GLN B 1 609 ? 130.991 172.273 195.113 1.00 64.23  ? 609  GLN B CD  1 
ATOM   11513 O  OE1 . GLN B 1 609 ? 132.118 172.544 194.699 1.00 64.23  ? 609  GLN B OE1 1 
ATOM   11514 N  NE2 . GLN B 1 609 ? 130.181 171.431 194.483 1.00 64.23  ? 609  GLN B NE2 1 
ATOM   11515 N  N   . ARG B 1 610 ? 133.825 173.908 199.730 1.00 70.41  ? 610  ARG B N   1 
ATOM   11516 C  CA  . ARG B 1 610 ? 134.794 174.795 200.358 1.00 70.41  ? 610  ARG B CA  1 
ATOM   11517 C  C   . ARG B 1 610 ? 135.774 174.040 201.250 1.00 70.41  ? 610  ARG B C   1 
ATOM   11518 O  O   . ARG B 1 610 ? 136.895 174.519 201.465 1.00 70.41  ? 610  ARG B O   1 
ATOM   11519 C  CB  . ARG B 1 610 ? 134.070 175.881 201.167 1.00 70.41  ? 610  ARG B CB  1 
ATOM   11520 C  CG  . ARG B 1 610 ? 134.979 176.916 201.815 1.00 70.41  ? 610  ARG B CG  1 
ATOM   11521 C  CD  . ARG B 1 610 ? 135.910 177.558 200.799 1.00 70.41  ? 610  ARG B CD  1 
ATOM   11522 N  NE  . ARG B 1 610 ? 136.831 178.501 201.422 1.00 70.41  ? 610  ARG B NE  1 
ATOM   11523 C  CZ  . ARG B 1 610 ? 137.975 178.899 200.882 1.00 70.41  ? 610  ARG B CZ  1 
ATOM   11524 N  NH1 . ARG B 1 610 ? 138.370 178.460 199.698 1.00 70.41  ? 610  ARG B NH1 1 
ATOM   11525 N  NH2 . ARG B 1 610 ? 138.742 179.758 201.547 1.00 70.41  ? 610  ARG B NH2 1 
ATOM   11526 N  N   . THR B 1 611 ? 135.397 172.868 201.751 1.00 53.12  ? 611  THR B N   1 
ATOM   11527 C  CA  . THR B 1 611 ? 136.237 172.076 202.638 1.00 53.12  ? 611  THR B CA  1 
ATOM   11528 C  C   . THR B 1 611 ? 137.139 171.176 201.806 1.00 53.12  ? 611  THR B C   1 
ATOM   11529 O  O   . THR B 1 611 ? 136.678 170.539 200.853 1.00 53.12  ? 611  THR B O   1 
ATOM   11530 C  CB  . THR B 1 611 ? 135.385 171.236 203.592 1.00 53.12  ? 611  THR B CB  1 
ATOM   11531 O  OG1 . THR B 1 611 ? 134.675 172.100 204.488 1.00 53.12  ? 611  THR B OG1 1 
ATOM   11532 C  CG2 . THR B 1 611 ? 136.258 170.291 204.400 1.00 53.12  ? 611  THR B CG2 1 
ATOM   11533 N  N   . THR B 1 612 ? 138.422 171.127 202.166 1.00 45.10  ? 612  THR B N   1 
ATOM   11534 C  CA  . THR B 1 612 ? 139.386 170.320 201.430 1.00 45.10  ? 612  THR B CA  1 
ATOM   11535 C  C   . THR B 1 612 ? 139.639 168.969 202.089 1.00 45.10  ? 612  THR B C   1 
ATOM   11536 O  O   . THR B 1 612 ? 139.766 167.956 201.393 1.00 45.10  ? 612  THR B O   1 
ATOM   11537 C  CB  . THR B 1 612 ? 140.706 171.083 201.284 1.00 45.10  ? 612  THR B CB  1 
ATOM   11538 O  OG1 . THR B 1 612 ? 140.479 172.296 200.557 1.00 45.10  ? 612  THR B OG1 1 
ATOM   11539 C  CG2 . THR B 1 612 ? 141.735 170.246 200.539 1.00 45.10  ? 612  THR B CG2 1 
ATOM   11540 N  N   . LEU B 1 613 ? 139.699 168.925 203.418 1.00 42.23  ? 613  LEU B N   1 
ATOM   11541 C  CA  . LEU B 1 613 ? 140.025 167.707 204.149 1.00 42.23  ? 613  LEU B CA  1 
ATOM   11542 C  C   . LEU B 1 613 ? 138.813 167.253 204.948 1.00 42.23  ? 613  LEU B C   1 
ATOM   11543 O  O   . LEU B 1 613 ? 138.252 168.030 205.728 1.00 42.23  ? 613  LEU B O   1 
ATOM   11544 C  CB  . LEU B 1 613 ? 141.221 167.928 205.075 1.00 42.23  ? 613  LEU B CB  1 
ATOM   11545 C  CG  . LEU B 1 613 ? 141.467 166.830 206.110 1.00 42.23  ? 613  LEU B CG  1 
ATOM   11546 C  CD1 . LEU B 1 613 ? 141.837 165.531 205.419 1.00 42.23  ? 613  LEU B CD1 1 
ATOM   11547 C  CD2 . LEU B 1 613 ? 142.547 167.245 207.093 1.00 42.23  ? 613  LEU B CD2 1 
ATOM   11548 N  N   . PHE B 1 614 ? 138.416 165.998 204.755 1.00 43.82  ? 614  PHE B N   1 
ATOM   11549 C  CA  . PHE B 1 614 ? 137.354 165.365 205.525 1.00 43.82  ? 614  PHE B CA  1 
ATOM   11550 C  C   . PHE B 1 614 ? 137.937 164.178 206.279 1.00 43.82  ? 614  PHE B C   1 
ATOM   11551 O  O   . PHE B 1 614 ? 138.646 163.355 205.691 1.00 43.82  ? 614  PHE B O   1 
ATOM   11552 C  CB  . PHE B 1 614 ? 136.208 164.901 204.620 1.00 43.82  ? 614  PHE B CB  1 
ATOM   11553 C  CG  . PHE B 1 614 ? 135.560 166.004 203.827 1.00 43.82  ? 614  PHE B CG  1 
ATOM   11554 C  CD1 . PHE B 1 614 ? 136.193 166.559 202.726 1.00 43.82  ? 614  PHE B CD1 1 
ATOM   11555 C  CD2 . PHE B 1 614 ? 134.306 166.474 204.175 1.00 43.82  ? 614  PHE B CD2 1 
ATOM   11556 C  CE1 . PHE B 1 614 ? 135.592 167.564 201.997 1.00 43.82  ? 614  PHE B CE1 1 
ATOM   11557 C  CE2 . PHE B 1 614 ? 133.701 167.481 203.449 1.00 43.82  ? 614  PHE B CE2 1 
ATOM   11558 C  CZ  . PHE B 1 614 ? 134.345 168.025 202.359 1.00 43.82  ? 614  PHE B CZ  1 
ATOM   11559 N  N   . ALA B 1 615 ? 137.637 164.086 207.571 1.00 45.57  ? 615  ALA B N   1 
ATOM   11560 C  CA  . ALA B 1 615 ? 138.217 163.064 208.428 1.00 45.57  ? 615  ALA B CA  1 
ATOM   11561 C  C   . ALA B 1 615 ? 137.128 162.271 209.138 1.00 45.57  ? 615  ALA B C   1 
ATOM   11562 O  O   . ALA B 1 615 ? 135.977 162.706 209.237 1.00 45.57  ? 615  ALA B O   1 
ATOM   11563 C  CB  . ALA B 1 615 ? 139.163 163.682 209.461 1.00 45.57  ? 615  ALA B CB  1 
ATOM   11564 N  N   . ARG B 1 616 ? 137.515 161.095 209.633 1.00 46.54  ? 616  ARG B N   1 
ATOM   11565 C  CA  . ARG B 1 616 ? 136.617 160.194 210.356 1.00 46.54  ? 616  ARG B CA  1 
ATOM   11566 C  C   . ARG B 1 616 ? 135.350 159.915 209.553 1.00 46.54  ? 616  ARG B C   1 
ATOM   11567 O  O   . ARG B 1 616 ? 134.230 160.181 209.992 1.00 46.54  ? 616  ARG B O   1 
ATOM   11568 C  CB  . ARG B 1 616 ? 136.278 160.752 211.739 1.00 46.54  ? 616  ARG B CB  1 
ATOM   11569 C  CG  . ARG B 1 616 ? 137.401 160.618 212.749 1.00 46.54  ? 616  ARG B CG  1 
ATOM   11570 C  CD  . ARG B 1 616 ? 136.870 160.675 214.170 1.00 46.54  ? 616  ARG B CD  1 
ATOM   11571 N  NE  . ARG B 1 616 ? 137.938 160.572 215.157 1.00 46.54  ? 616  ARG B NE  1 
ATOM   11572 C  CZ  . ARG B 1 616 ? 138.467 161.605 215.797 1.00 46.54  ? 616  ARG B CZ  1 
ATOM   11573 N  NH1 . ARG B 1 616 ? 138.048 162.841 215.578 1.00 46.54  ? 616  ARG B NH1 1 
ATOM   11574 N  NH2 . ARG B 1 616 ? 139.438 161.394 216.680 1.00 46.54  ? 616  ARG B NH2 1 
ATOM   11575 N  N   . LEU B 1 617 ? 135.538 159.365 208.358 1.00 45.98  ? 617  LEU B N   1 
ATOM   11576 C  CA  . LEU B 1 617 ? 134.444 159.117 207.431 1.00 45.98  ? 617  LEU B CA  1 
ATOM   11577 C  C   . LEU B 1 617 ? 134.172 157.624 207.319 1.00 45.98  ? 617  LEU B C   1 
ATOM   11578 O  O   . LEU B 1 617 ? 135.096 156.831 207.113 1.00 45.98  ? 617  LEU B O   1 
ATOM   11579 C  CB  . LEU B 1 617 ? 134.764 159.688 206.050 1.00 45.98  ? 617  LEU B CB  1 
ATOM   11580 C  CG  . LEU B 1 617 ? 134.833 161.208 205.921 1.00 45.98  ? 617  LEU B CG  1 
ATOM   11581 C  CD1 . LEU B 1 617 ? 134.925 161.590 204.458 1.00 45.98  ? 617  LEU B CD1 1 
ATOM   11582 C  CD2 . LEU B 1 617 ? 133.627 161.860 206.573 1.00 45.98  ? 617  LEU B CD2 1 
ATOM   11583 N  N   . THR B 1 618 ? 132.907 157.249 207.461 1.00 52.71  ? 618  THR B N   1 
ATOM   11584 C  CA  . THR B 1 618 ? 132.467 155.910 207.121 1.00 52.71  ? 618  THR B CA  1 
ATOM   11585 C  C   . THR B 1 618 ? 132.266 155.806 205.613 1.00 52.71  ? 618  THR B C   1 
ATOM   11586 O  O   . THR B 1 618 ? 132.129 156.822 204.927 1.00 52.71  ? 618  THR B O   1 
ATOM   11587 C  CB  . THR B 1 618 ? 131.172 155.579 207.858 1.00 52.71  ? 618  THR B CB  1 
ATOM   11588 O  OG1 . THR B 1 618 ? 130.145 156.494 207.458 1.00 52.71  ? 618  THR B OG1 1 
ATOM   11589 C  CG2 . THR B 1 618 ? 131.378 155.681 209.360 1.00 52.71  ? 618  THR B CG2 1 
ATOM   11590 N  N   . PRO B 1 619 ? 132.267 154.588 205.063 1.00 53.66  ? 619  PRO B N   1 
ATOM   11591 C  CA  . PRO B 1 619 ? 132.048 154.449 203.613 1.00 53.66  ? 619  PRO B CA  1 
ATOM   11592 C  C   . PRO B 1 619 ? 130.750 155.073 203.132 1.00 53.66  ? 619  PRO B C   1 
ATOM   11593 O  O   . PRO B 1 619 ? 130.708 155.614 202.018 1.00 53.66  ? 619  PRO B O   1 
ATOM   11594 C  CB  . PRO B 1 619 ? 132.057 152.929 203.411 1.00 53.66  ? 619  PRO B CB  1 
ATOM   11595 C  CG  . PRO B 1 619 ? 132.945 152.432 204.500 1.00 53.66  ? 619  PRO B CG  1 
ATOM   11596 C  CD  . PRO B 1 619 ? 132.644 153.305 205.683 1.00 53.66  ? 619  PRO B CD  1 
ATOM   11597 N  N   . MET B 1 620 ? 129.688 155.020 203.938 1.00 58.03  ? 620  MET B N   1 
ATOM   11598 C  CA  . MET B 1 620 ? 128.455 155.712 203.577 1.00 58.03  ? 620  MET B CA  1 
ATOM   11599 C  C   . MET B 1 620 ? 128.679 157.216 203.490 1.00 58.03  ? 620  MET B C   1 
ATOM   11600 O  O   . MET B 1 620 ? 128.152 157.880 202.589 1.00 58.03  ? 620  MET B O   1 
ATOM   11601 C  CB  . MET B 1 620 ? 127.355 155.388 204.586 1.00 58.03  ? 620  MET B CB  1 
ATOM   11602 C  CG  . MET B 1 620 ? 127.234 153.910 204.922 1.00 58.03  ? 620  MET B CG  1 
ATOM   11603 S  SD  . MET B 1 620 ? 126.321 152.973 203.682 1.00 58.03  ? 620  MET B SD  1 
ATOM   11604 C  CE  . MET B 1 620 ? 127.662 152.190 202.789 1.00 58.03  ? 620  MET B CE  1 
ATOM   11605 N  N   . HIS B 1 621 ? 129.456 157.773 204.424 1.00 53.98  ? 621  HIS B N   1 
ATOM   11606 C  CA  . HIS B 1 621 ? 129.772 159.196 204.373 1.00 53.98  ? 621  HIS B CA  1 
ATOM   11607 C  C   . HIS B 1 621 ? 130.561 159.541 203.117 1.00 53.98  ? 621  HIS B C   1 
ATOM   11608 O  O   . HIS B 1 621 ? 130.311 160.572 202.481 1.00 53.98  ? 621  HIS B O   1 
ATOM   11609 C  CB  . HIS B 1 621 ? 130.550 159.607 205.621 1.00 53.98  ? 621  HIS B CB  1 
ATOM   11610 C  CG  . HIS B 1 621 ? 129.777 159.456 206.893 1.00 53.98  ? 621  HIS B CG  1 
ATOM   11611 N  ND1 . HIS B 1 621 ? 130.383 159.225 208.109 1.00 53.98  ? 621  HIS B ND1 1 
ATOM   11612 C  CD2 . HIS B 1 621 ? 128.447 159.506 207.140 1.00 53.98  ? 621  HIS B CD2 1 
ATOM   11613 C  CE1 . HIS B 1 621 ? 129.459 159.137 209.049 1.00 53.98  ? 621  HIS B CE1 1 
ATOM   11614 N  NE2 . HIS B 1 621 ? 128.276 159.303 208.487 1.00 53.98  ? 621  HIS B NE2 1 
ATOM   11615 N  N   . LYS B 1 622 ? 131.524 158.692 202.748 1.00 48.39  ? 622  LYS B N   1 
ATOM   11616 C  CA  . LYS B 1 622 ? 132.288 158.920 201.526 1.00 48.39  ? 622  LYS B CA  1 
ATOM   11617 C  C   . LYS B 1 622 ? 131.378 158.902 200.306 1.00 48.39  ? 622  LYS B C   1 
ATOM   11618 O  O   . LYS B 1 622 ? 131.480 159.764 199.425 1.00 48.39  ? 622  LYS B O   1 
ATOM   11619 C  CB  . LYS B 1 622 ? 133.386 157.866 201.389 1.00 48.39  ? 622  LYS B CB  1 
ATOM   11620 C  CG  . LYS B 1 622 ? 134.464 157.934 202.454 1.00 48.39  ? 622  LYS B CG  1 
ATOM   11621 C  CD  . LYS B 1 622 ? 135.763 157.335 201.944 1.00 48.39  ? 622  LYS B CD  1 
ATOM   11622 C  CE  . LYS B 1 622 ? 136.550 156.683 203.067 1.00 48.39  ? 622  LYS B CE  1 
ATOM   11623 N  NZ  . LYS B 1 622 ? 137.905 156.256 202.622 1.00 48.39  ? 622  LYS B NZ  1 
ATOM   11624 N  N   . GLU B 1 623 ? 130.475 157.920 200.241 1.00 54.66  ? 623  GLU B N   1 
ATOM   11625 C  CA  . GLU B 1 623 ? 129.556 157.837 199.111 1.00 54.66  ? 623  GLU B CA  1 
ATOM   11626 C  C   . GLU B 1 623 ? 128.662 159.067 199.036 1.00 54.66  ? 623  GLU B C   1 
ATOM   11627 O  O   . GLU B 1 623 ? 128.450 159.623 197.952 1.00 54.66  ? 623  GLU B O   1 
ATOM   11628 C  CB  . GLU B 1 623 ? 128.713 156.566 199.212 1.00 54.66  ? 623  GLU B CB  1 
ATOM   11629 C  CG  . GLU B 1 623 ? 127.512 156.546 198.282 1.00 54.66  ? 623  GLU B CG  1 
ATOM   11630 C  CD  . GLU B 1 623 ? 126.626 155.336 198.500 1.00 54.66  ? 623  GLU B CD  1 
ATOM   11631 O  OE1 . GLU B 1 623 ? 126.703 154.729 199.589 1.00 54.66  ? 623  GLU B OE1 1 
ATOM   11632 O  OE2 . GLU B 1 623 ? 125.850 154.993 197.583 1.00 54.66  ? 623  GLU B OE2 1 
ATOM   11633 N  N   . ARG B 1 624 ? 128.138 159.515 200.179 1.00 58.50  ? 624  ARG B N   1 
ATOM   11634 C  CA  . ARG B 1 624 ? 127.276 160.692 200.185 1.00 58.50  ? 624  ARG B CA  1 
ATOM   11635 C  C   . ARG B 1 624 ? 128.036 161.939 199.750 1.00 58.50  ? 624  ARG B C   1 
ATOM   11636 O  O   . ARG B 1 624 ? 127.529 162.737 198.951 1.00 58.50  ? 624  ARG B O   1 
ATOM   11637 C  CB  . ARG B 1 624 ? 126.669 160.893 201.572 1.00 58.50  ? 624  ARG B CB  1 
ATOM   11638 C  CG  . ARG B 1 624 ? 125.670 162.033 201.650 1.00 58.50  ? 624  ARG B CG  1 
ATOM   11639 C  CD  . ARG B 1 624 ? 125.135 162.203 203.061 1.00 58.50  ? 624  ARG B CD  1 
ATOM   11640 N  NE  . ARG B 1 624 ? 124.401 163.452 203.221 1.00 58.50  ? 624  ARG B NE  1 
ATOM   11641 C  CZ  . ARG B 1 624 ? 124.063 163.978 204.390 1.00 58.50  ? 624  ARG B CZ  1 
ATOM   11642 N  NH1 . ARG B 1 624 ? 124.375 163.384 205.531 1.00 58.50  ? 624  ARG B NH1 1 
ATOM   11643 N  NH2 . ARG B 1 624 ? 123.395 165.127 204.416 1.00 58.50  ? 624  ARG B NH2 1 
ATOM   11644 N  N   . ILE B 1 625 ? 129.255 162.124 200.262 1.00 50.33  ? 625  ILE B N   1 
ATOM   11645 C  CA  . ILE B 1 625 ? 130.042 163.302 199.907 1.00 50.33  ? 625  ILE B CA  1 
ATOM   11646 C  C   . ILE B 1 625 ? 130.365 163.298 198.419 1.00 50.33  ? 625  ILE B C   1 
ATOM   11647 O  O   . ILE B 1 625 ? 130.279 164.334 197.748 1.00 50.33  ? 625  ILE B O   1 
ATOM   11648 C  CB  . ILE B 1 625 ? 131.316 163.376 200.768 1.00 50.33  ? 625  ILE B CB  1 
ATOM   11649 C  CG1 . ILE B 1 625 ? 130.978 163.864 202.177 1.00 50.33  ? 625  ILE B CG1 1 
ATOM   11650 C  CG2 . ILE B 1 625 ? 132.344 164.291 200.129 1.00 50.33  ? 625  ILE B CG2 1 
ATOM   11651 C  CD1 . ILE B 1 625 ? 131.964 163.415 203.231 1.00 50.33  ? 625  ILE B CD1 1 
ATOM   11652 N  N   . VAL B 1 626 ? 130.735 162.135 197.877 1.00 47.25  ? 626  VAL B N   1 
ATOM   11653 C  CA  . VAL B 1 626 ? 131.027 162.046 196.449 1.00 47.25  ? 626  VAL B CA  1 
ATOM   11654 C  C   . VAL B 1 626 ? 129.777 162.334 195.626 1.00 47.25  ? 626  VAL B C   1 
ATOM   11655 O  O   . VAL B 1 626 ? 129.833 163.040 194.612 1.00 47.25  ? 626  VAL B O   1 
ATOM   11656 C  CB  . VAL B 1 626 ? 131.627 160.670 196.113 1.00 47.25  ? 626  VAL B CB  1 
ATOM   11657 C  CG1 . VAL B 1 626 ? 131.708 160.485 194.615 1.00 47.25  ? 626  VAL B CG1 1 
ATOM   11658 C  CG2 . VAL B 1 626 ? 133.004 160.535 196.733 1.00 47.25  ? 626  VAL B CG2 1 
ATOM   11659 N  N   . THR B 1 627 ? 128.628 161.796 196.047 1.00 50.11  ? 627  THR B N   1 
ATOM   11660 C  CA  . THR B 1 627 ? 127.392 162.016 195.304 1.00 50.11  ? 627  THR B CA  1 
ATOM   11661 C  C   . THR B 1 627 ? 127.004 163.489 195.290 1.00 50.11  ? 627  THR B C   1 
ATOM   11662 O  O   . THR B 1 627 ? 126.596 164.021 194.252 1.00 50.11  ? 627  THR B O   1 
ATOM   11663 C  CB  . THR B 1 627 ? 126.263 161.174 195.899 1.00 50.11  ? 627  THR B CB  1 
ATOM   11664 O  OG1 . THR B 1 627 ? 126.627 159.789 195.861 1.00 50.11  ? 627  THR B OG1 1 
ATOM   11665 C  CG2 . THR B 1 627 ? 124.975 161.375 195.115 1.00 50.11  ? 627  THR B CG2 1 
ATOM   11666 N  N   . LEU B 1 628 ? 127.133 164.169 196.429 1.00 53.64  ? 628  LEU B N   1 
ATOM   11667 C  CA  . LEU B 1 628 ? 126.724 165.566 196.507 1.00 53.64  ? 628  LEU B CA  1 
ATOM   11668 C  C   . LEU B 1 628 ? 127.739 166.524 195.899 1.00 53.64  ? 628  LEU B C   1 
ATOM   11669 O  O   . LEU B 1 628 ? 127.461 167.726 195.824 1.00 53.64  ? 628  LEU B O   1 
ATOM   11670 C  CB  . LEU B 1 628 ? 126.454 165.959 197.961 1.00 53.64  ? 628  LEU B CB  1 
ATOM   11671 C  CG  . LEU B 1 628 ? 125.412 165.121 198.706 1.00 53.64  ? 628  LEU B CG  1 
ATOM   11672 C  CD1 . LEU B 1 628 ? 125.150 165.692 200.087 1.00 53.64  ? 628  LEU B CD1 1 
ATOM   11673 C  CD2 . LEU B 1 628 ? 124.120 165.022 197.912 1.00 53.64  ? 628  LEU B CD2 1 
ATOM   11674 N  N   . LEU B 1 629 ? 128.902 166.034 195.470 1.00 47.80  ? 629  LEU B N   1 
ATOM   11675 C  CA  . LEU B 1 629 ? 129.917 166.900 194.886 1.00 47.80  ? 629  LEU B CA  1 
ATOM   11676 C  C   . LEU B 1 629 ? 129.768 167.073 193.380 1.00 47.80  ? 629  LEU B C   1 
ATOM   11677 O  O   . LEU B 1 629 ? 130.481 167.897 192.799 1.00 47.80  ? 629  LEU B O   1 
ATOM   11678 C  CB  . LEU B 1 629 ? 131.313 166.357 195.197 1.00 47.80  ? 629  LEU B CB  1 
ATOM   11679 C  CG  . LEU B 1 629 ? 132.024 166.959 196.409 1.00 47.80  ? 629  LEU B CG  1 
ATOM   11680 C  CD1 . LEU B 1 629 ? 133.379 166.302 196.618 1.00 47.80  ? 629  LEU B CD1 1 
ATOM   11681 C  CD2 . LEU B 1 629 ? 132.173 168.460 196.241 1.00 47.80  ? 629  LEU B CD2 1 
ATOM   11682 N  N   . LYS B 1 630 ? 128.870 166.327 192.735 1.00 47.56  ? 630  LYS B N   1 
ATOM   11683 C  CA  . LYS B 1 630 ? 128.724 166.389 191.287 1.00 47.56  ? 630  LYS B CA  1 
ATOM   11684 C  C   . LYS B 1 630 ? 127.551 167.241 190.825 1.00 47.56  ? 630  LYS B C   1 
ATOM   11685 O  O   . LYS B 1 630 ? 127.480 167.569 189.635 1.00 47.56  ? 630  LYS B O   1 
ATOM   11686 C  CB  . LYS B 1 630 ? 128.558 164.980 190.704 1.00 47.56  ? 630  LYS B CB  1 
ATOM   11687 C  CG  . LYS B 1 630 ? 129.352 163.904 191.420 1.00 47.56  ? 630  LYS B CG  1 
ATOM   11688 C  CD  . LYS B 1 630 ? 129.120 162.540 190.793 1.00 47.56  ? 630  LYS B CD  1 
ATOM   11689 C  CE  . LYS B 1 630 ? 127.639 162.215 190.709 1.00 47.56  ? 630  LYS B CE  1 
ATOM   11690 N  NZ  . LYS B 1 630 ? 127.400 160.866 190.126 1.00 47.56  ? 630  LYS B NZ  1 
ATOM   11691 N  N   . ARG B 1 631 ? 126.633 167.600 191.724 1.00 55.58  ? 631  ARG B N   1 
ATOM   11692 C  CA  . ARG B 1 631 ? 125.402 168.264 191.305 1.00 55.58  ? 631  ARG B CA  1 
ATOM   11693 C  C   . ARG B 1 631 ? 125.677 169.638 190.705 1.00 55.58  ? 631  ARG B C   1 
ATOM   11694 O  O   . ARG B 1 631 ? 125.044 170.036 189.721 1.00 55.58  ? 631  ARG B O   1 
ATOM   11695 C  CB  . ARG B 1 631 ? 124.435 168.372 192.486 1.00 55.58  ? 631  ARG B CB  1 
ATOM   11696 C  CG  . ARG B 1 631 ? 125.076 168.797 193.794 1.00 55.58  ? 631  ARG B CG  1 
ATOM   11697 C  CD  . ARG B 1 631 ? 124.241 168.336 194.975 1.00 55.58  ? 631  ARG B CD  1 
ATOM   11698 N  NE  . ARG B 1 631 ? 122.816 168.523 194.732 1.00 55.58  ? 631  ARG B NE  1 
ATOM   11699 C  CZ  . ARG B 1 631 ? 121.854 168.059 195.517 1.00 55.58  ? 631  ARG B CZ  1 
ATOM   11700 N  NH1 . ARG B 1 631 ? 122.128 167.370 196.612 1.00 55.58  ? 631  ARG B NH1 1 
ATOM   11701 N  NH2 . ARG B 1 631 ? 120.585 168.293 195.195 1.00 55.58  ? 631  ARG B NH2 1 
ATOM   11702 N  N   . GLU B 1 632 ? 126.621 170.381 191.282 1.00 58.18  ? 632  GLU B N   1 
ATOM   11703 C  CA  . GLU B 1 632 ? 126.895 171.749 190.843 1.00 58.18  ? 632  GLU B CA  1 
ATOM   11704 C  C   . GLU B 1 632 ? 127.847 171.756 189.643 1.00 58.18  ? 632  GLU B C   1 
ATOM   11705 O  O   . GLU B 1 632 ? 128.878 172.427 189.623 1.00 58.18  ? 632  GLU B O   1 
ATOM   11706 C  CB  . GLU B 1 632 ? 127.447 172.569 192.003 1.00 58.18  ? 632  GLU B CB  1 
ATOM   11707 C  CG  . GLU B 1 632 ? 127.175 174.066 191.898 1.00 58.18  ? 632  GLU B CG  1 
ATOM   11708 C  CD  . GLU B 1 632 ? 128.332 174.838 191.297 1.00 58.18  ? 632  GLU B CD  1 
ATOM   11709 O  OE1 . GLU B 1 632 ? 129.495 174.438 191.515 1.00 58.18  ? 632  GLU B OE1 1 
ATOM   11710 O  OE2 . GLU B 1 632 ? 128.079 175.846 190.604 1.00 58.18  ? 632  GLU B OE2 1 
ATOM   11711 N  N   . GLY B 1 633 ? 127.474 170.984 188.623 1.00 51.99  ? 633  GLY B N   1 
ATOM   11712 C  CA  . GLY B 1 633 ? 128.196 170.964 187.365 1.00 51.99  ? 633  GLY B CA  1 
ATOM   11713 C  C   . GLY B 1 633 ? 129.662 170.600 187.473 1.00 51.99  ? 633  GLY B C   1 
ATOM   11714 O  O   . GLY B 1 633 ? 130.506 171.215 186.814 1.00 51.99  ? 633  GLY B O   1 
ATOM   11715 N  N   . HIS B 1 634 ? 129.984 169.605 188.298 1.00 49.92  ? 634  HIS B N   1 
ATOM   11716 C  CA  . HIS B 1 634 ? 131.363 169.179 188.510 1.00 49.92  ? 634  HIS B CA  1 
ATOM   11717 C  C   . HIS B 1 634 ? 131.481 167.696 188.198 1.00 49.92  ? 634  HIS B C   1 
ATOM   11718 O  O   . HIS B 1 634 ? 130.646 166.899 188.638 1.00 49.92  ? 634  HIS B O   1 
ATOM   11719 C  CB  . HIS B 1 634 ? 131.814 169.459 189.946 1.00 49.92  ? 634  HIS B CB  1 
ATOM   11720 C  CG  . HIS B 1 634 ? 131.958 170.915 190.262 1.00 49.92  ? 634  HIS B CG  1 
ATOM   11721 N  ND1 . HIS B 1 634 ? 132.759 171.761 189.527 1.00 49.92  ? 634  HIS B ND1 1 
ATOM   11722 C  CD2 . HIS B 1 634 ? 131.405 171.674 191.238 1.00 49.92  ? 634  HIS B CD2 1 
ATOM   11723 C  CE1 . HIS B 1 634 ? 132.693 172.979 190.034 1.00 49.92  ? 634  HIS B CE1 1 
ATOM   11724 N  NE2 . HIS B 1 634 ? 131.878 172.953 191.073 1.00 49.92  ? 634  HIS B NE2 1 
ATOM   11725 N  N   . VAL B 1 635 ? 132.511 167.331 187.442 1.00 42.86  ? 635  VAL B N   1 
ATOM   11726 C  CA  . VAL B 1 635 ? 132.811 165.927 187.179 1.00 42.86  ? 635  VAL B CA  1 
ATOM   11727 C  C   . VAL B 1 635 ? 133.765 165.436 188.261 1.00 42.86  ? 635  VAL B C   1 
ATOM   11728 O  O   . VAL B 1 635 ? 134.888 165.934 188.384 1.00 42.86  ? 635  VAL B O   1 
ATOM   11729 C  CB  . VAL B 1 635 ? 133.413 165.740 185.780 1.00 42.86  ? 635  VAL B CB  1 
ATOM   11730 C  CG1 . VAL B 1 635 ? 133.987 164.341 185.634 1.00 42.86  ? 635  VAL B CG1 1 
ATOM   11731 C  CG2 . VAL B 1 635 ? 132.363 166.007 184.713 1.00 42.86  ? 635  VAL B CG2 1 
ATOM   11732 N  N   . VAL B 1 636 ? 133.323 164.455 189.041 1.00 41.06  ? 636  VAL B N   1 
ATOM   11733 C  CA  . VAL B 1 636 ? 134.027 164.020 190.242 1.00 41.06  ? 636  VAL B CA  1 
ATOM   11734 C  C   . VAL B 1 636 ? 134.719 162.693 189.966 1.00 41.06  ? 636  VAL B C   1 
ATOM   11735 O  O   . VAL B 1 636 ? 134.114 161.764 189.414 1.00 41.06  ? 636  VAL B O   1 
ATOM   11736 C  CB  . VAL B 1 636 ? 133.070 163.905 191.441 1.00 41.06  ? 636  VAL B CB  1 
ATOM   11737 C  CG1 . VAL B 1 636 ? 133.734 163.162 192.585 1.00 41.06  ? 636  VAL B CG1 1 
ATOM   11738 C  CG2 . VAL B 1 636 ? 132.634 165.287 191.892 1.00 41.06  ? 636  VAL B CG2 1 
ATOM   11739 N  N   . GLY B 1 637 ? 135.992 162.613 190.343 1.00 38.50  ? 637  GLY B N   1 
ATOM   11740 C  CA  . GLY B 1 637 ? 136.723 161.366 190.293 1.00 38.50  ? 637  GLY B CA  1 
ATOM   11741 C  C   . GLY B 1 637 ? 137.125 160.895 191.672 1.00 38.50  ? 637  GLY B C   1 
ATOM   11742 O  O   . GLY B 1 637 ? 137.660 161.670 192.470 1.00 38.50  ? 637  GLY B O   1 
ATOM   11743 N  N   . PHE B 1 638 ? 136.871 159.626 191.968 1.00 37.31  ? 638  PHE B N   1 
ATOM   11744 C  CA  . PHE B 1 638 ? 137.195 159.047 193.263 1.00 37.31  ? 638  PHE B CA  1 
ATOM   11745 C  C   . PHE B 1 638 ? 138.272 157.990 193.080 1.00 37.31  ? 638  PHE B C   1 
ATOM   11746 O  O   . PHE B 1 638 ? 138.137 157.103 192.232 1.00 37.31  ? 638  PHE B O   1 
ATOM   11747 C  CB  . PHE B 1 638 ? 135.959 158.436 193.929 1.00 37.31  ? 638  PHE B CB  1 
ATOM   11748 C  CG  . PHE B 1 638 ? 136.213 157.921 195.318 1.00 37.31  ? 638  PHE B CG  1 
ATOM   11749 C  CD1 . PHE B 1 638 ? 136.113 158.764 196.410 1.00 37.31  ? 638  PHE B CD1 1 
ATOM   11750 C  CD2 . PHE B 1 638 ? 136.552 156.596 195.531 1.00 37.31  ? 638  PHE B CD2 1 
ATOM   11751 C  CE1 . PHE B 1 638 ? 136.346 158.296 197.688 1.00 37.31  ? 638  PHE B CE1 1 
ATOM   11752 C  CE2 . PHE B 1 638 ? 136.788 156.123 196.807 1.00 37.31  ? 638  PHE B CE2 1 
ATOM   11753 C  CZ  . PHE B 1 638 ? 136.684 156.974 197.886 1.00 37.31  ? 638  PHE B CZ  1 
ATOM   11754 N  N   . MET B 1 639 ? 139.334 158.088 193.873 1.00 34.72  ? 639  MET B N   1 
ATOM   11755 C  CA  . MET B 1 639 ? 140.437 157.138 193.838 1.00 34.72  ? 639  MET B CA  1 
ATOM   11756 C  C   . MET B 1 639 ? 140.484 156.388 195.162 1.00 34.72  ? 639  MET B C   1 
ATOM   11757 O  O   . MET B 1 639 ? 140.644 157.003 196.222 1.00 34.72  ? 639  MET B O   1 
ATOM   11758 C  CB  . MET B 1 639 ? 141.764 157.846 193.572 1.00 34.72  ? 639  MET B CB  1 
ATOM   11759 C  CG  . MET B 1 639 ? 142.954 156.909 193.465 1.00 34.72  ? 639  MET B CG  1 
ATOM   11760 S  SD  . MET B 1 639 ? 144.518 157.787 193.298 1.00 34.72  ? 639  MET B SD  1 
ATOM   11761 C  CE  . MET B 1 639 ? 145.630 156.427 192.961 1.00 34.72  ? 639  MET B CE  1 
ATOM   11762 N  N   . GLY B 1 640 ? 140.348 155.068 195.098 1.00 36.67  ? 640  GLY B N   1 
ATOM   11763 C  CA  . GLY B 1 640 ? 140.355 154.251 196.295 1.00 36.67  ? 640  GLY B CA  1 
ATOM   11764 C  C   . GLY B 1 640 ? 140.641 152.809 195.954 1.00 36.67  ? 640  GLY B C   1 
ATOM   11765 O  O   . GLY B 1 640 ? 140.415 152.365 194.824 1.00 36.67  ? 640  GLY B O   1 
ATOM   11766 N  N   . ASP B 1 641 ? 141.149 152.073 196.939 1.00 43.00  ? 641  ASP B N   1 
ATOM   11767 C  CA  . ASP B 1 641 ? 141.502 150.669 196.760 1.00 43.00  ? 641  ASP B CA  1 
ATOM   11768 C  C   . ASP B 1 641 ? 141.118 149.859 197.991 1.00 43.00  ? 641  ASP B C   1 
ATOM   11769 O  O   . ASP B 1 641 ? 141.836 148.941 198.400 1.00 43.00  ? 641  ASP B O   1 
ATOM   11770 C  CB  . ASP B 1 641 ? 142.990 150.512 196.451 1.00 43.00  ? 641  ASP B CB  1 
ATOM   11771 C  CG  . ASP B 1 641 ? 143.877 151.165 197.495 1.00 43.00  ? 641  ASP B CG  1 
ATOM   11772 O  OD1 . ASP B 1 641 ? 143.343 151.842 198.398 1.00 43.00  ? 641  ASP B OD1 1 
ATOM   11773 O  OD2 . ASP B 1 641 ? 145.112 151.004 197.409 1.00 43.00  ? 641  ASP B OD2 1 
ATOM   11774 N  N   . GLY B 1 642 ? 139.979 150.189 198.601 1.00 43.38  ? 642  GLY B N   1 
ATOM   11775 C  CA  . GLY B 1 642 ? 139.499 149.502 199.777 1.00 43.38  ? 642  GLY B CA  1 
ATOM   11776 C  C   . GLY B 1 642 ? 138.346 148.559 199.463 1.00 43.38  ? 642  GLY B C   1 
ATOM   11777 O  O   . GLY B 1 642 ? 137.805 148.529 198.359 1.00 43.38  ? 642  GLY B O   1 
ATOM   11778 N  N   . ILE B 1 643 ? 137.979 147.773 200.478 1.00 42.62  ? 643  ILE B N   1 
ATOM   11779 C  CA  . ILE B 1 643 ? 136.880 146.823 200.326 1.00 42.62  ? 643  ILE B CA  1 
ATOM   11780 C  C   . ILE B 1 643 ? 135.565 147.556 200.095 1.00 42.62  ? 643  ILE B C   1 
ATOM   11781 O  O   . ILE B 1 643 ? 134.766 147.174 199.232 1.00 42.62  ? 643  ILE B O   1 
ATOM   11782 C  CB  . ILE B 1 643 ? 136.800 145.897 201.554 1.00 42.62  ? 643  ILE B CB  1 
ATOM   11783 C  CG1 . ILE B 1 643 ? 138.010 144.965 201.606 1.00 42.62  ? 643  ILE B CG1 1 
ATOM   11784 C  CG2 . ILE B 1 643 ? 135.513 145.089 201.532 1.00 42.62  ? 643  ILE B CG2 1 
ATOM   11785 C  CD1 . ILE B 1 643 ? 137.965 143.978 202.752 1.00 42.62  ? 643  ILE B CD1 1 
ATOM   11786 N  N   . ASN B 1 644 ? 135.321 148.621 200.855 1.00 45.28  ? 644  ASN B N   1 
ATOM   11787 C  CA  . ASN B 1 644 ? 134.057 149.341 200.811 1.00 45.28  ? 644  ASN B CA  1 
ATOM   11788 C  C   . ASN B 1 644 ? 134.093 150.549 199.884 1.00 45.28  ? 644  ASN B C   1 
ATOM   11789 O  O   . ASN B 1 644 ? 133.219 151.415 199.981 1.00 45.28  ? 644  ASN B O   1 
ATOM   11790 C  CB  . ASN B 1 644 ? 133.656 149.778 202.219 1.00 45.28  ? 644  ASN B CB  1 
ATOM   11791 C  CG  . ASN B 1 644 ? 133.797 148.664 203.234 1.00 45.28  ? 644  ASN B CG  1 
ATOM   11792 O  OD1 . ASN B 1 644 ? 134.777 148.606 203.975 1.00 45.28  ? 644  ASN B OD1 1 
ATOM   11793 N  ND2 . ASN B 1 644 ? 132.814 147.773 203.277 1.00 45.28  ? 644  ASN B ND2 1 
ATOM   11794 N  N   . ASP B 1 645 ? 135.078 150.631 198.995 1.00 43.17  ? 645  ASP B N   1 
ATOM   11795 C  CA  . ASP B 1 645 ? 135.169 151.741 198.057 1.00 43.17  ? 645  ASP B CA  1 
ATOM   11796 C  C   . ASP B 1 645 ? 134.340 151.527 196.799 1.00 43.17  ? 645  ASP B C   1 
ATOM   11797 O  O   . ASP B 1 645 ? 134.289 152.425 195.952 1.00 43.17  ? 645  ASP B O   1 
ATOM   11798 C  CB  . ASP B 1 645 ? 136.629 151.992 197.671 1.00 43.17  ? 645  ASP B CB  1 
ATOM   11799 C  CG  . ASP B 1 645 ? 137.440 152.573 198.810 1.00 43.17  ? 645  ASP B CG  1 
ATOM   11800 O  OD1 . ASP B 1 645 ? 136.839 153.193 199.713 1.00 43.17  ? 645  ASP B OD1 1 
ATOM   11801 O  OD2 . ASP B 1 645 ? 138.679 152.422 198.797 1.00 43.17  ? 645  ASP B OD2 1 
ATOM   11802 N  N   . ALA B 1 646 ? 133.695 150.370 196.652 1.00 38.29  ? 646  ALA B N   1 
ATOM   11803 C  CA  . ALA B 1 646 ? 132.881 150.128 195.462 1.00 38.29  ? 646  ALA B CA  1 
ATOM   11804 C  C   . ALA B 1 646 ? 131.717 151.103 195.334 1.00 38.29  ? 646  ALA B C   1 
ATOM   11805 O  O   . ALA B 1 646 ? 131.524 151.650 194.233 1.00 38.29  ? 646  ALA B O   1 
ATOM   11806 C  CB  . ALA B 1 646 ? 132.404 148.672 195.450 1.00 38.29  ? 646  ALA B CB  1 
ATOM   11807 N  N   . PRO B 1 647 ? 130.904 151.359 196.370 1.00 41.78  ? 647  PRO B N   1 
ATOM   11808 C  CA  . PRO B 1 647 ? 129.869 152.396 196.218 1.00 41.78  ? 647  PRO B CA  1 
ATOM   11809 C  C   . PRO B 1 647 ? 130.437 153.764 195.892 1.00 41.78  ? 647  PRO B C   1 
ATOM   11810 O  O   . PRO B 1 647 ? 129.852 154.497 195.086 1.00 41.78  ? 647  PRO B O   1 
ATOM   11811 C  CB  . PRO B 1 647 ? 129.159 152.384 197.579 1.00 41.78  ? 647  PRO B CB  1 
ATOM   11812 C  CG  . PRO B 1 647 ? 129.424 151.037 198.130 1.00 41.78  ? 647  PRO B CG  1 
ATOM   11813 C  CD  . PRO B 1 647 ? 130.812 150.703 197.686 1.00 41.78  ? 647  PRO B CD  1 
ATOM   11814 N  N   . ALA B 1 648 ? 131.573 154.128 196.491 1.00 37.47  ? 648  ALA B N   1 
ATOM   11815 C  CA  . ALA B 1 648 ? 132.171 155.428 196.207 1.00 37.47  ? 648  ALA B CA  1 
ATOM   11816 C  C   . ALA B 1 648 ? 132.698 155.495 194.781 1.00 37.47  ? 648  ALA B C   1 
ATOM   11817 O  O   . ALA B 1 648 ? 132.505 156.502 194.089 1.00 37.47  ? 648  ALA B O   1 
ATOM   11818 C  CB  . ALA B 1 648 ? 133.287 155.723 197.206 1.00 37.47  ? 648  ALA B CB  1 
ATOM   11819 N  N   . LEU B 1 649 ? 133.371 154.437 194.326 1.00 36.46  ? 649  LEU B N   1 
ATOM   11820 C  CA  . LEU B 1 649 ? 133.895 154.424 192.964 1.00 36.46  ? 649  LEU B CA  1 
ATOM   11821 C  C   . LEU B 1 649 ? 132.770 154.458 191.937 1.00 36.46  ? 649  LEU B C   1 
ATOM   11822 O  O   . LEU B 1 649 ? 132.872 155.155 190.922 1.00 36.46  ? 649  LEU B O   1 
ATOM   11823 C  CB  . LEU B 1 649 ? 134.777 153.194 192.752 1.00 36.46  ? 649  LEU B CB  1 
ATOM   11824 C  CG  . LEU B 1 649 ? 136.148 153.203 193.430 1.00 36.46  ? 649  LEU B CG  1 
ATOM   11825 C  CD1 . LEU B 1 649 ? 136.645 151.785 193.648 1.00 36.46  ? 649  LEU B CD1 1 
ATOM   11826 C  CD2 . LEU B 1 649 ? 137.146 153.998 192.611 1.00 36.46  ? 649  LEU B CD2 1 
ATOM   11827 N  N   . ARG B 1 650 ? 131.690 153.713 192.181 1.00 40.65  ? 650  ARG B N   1 
ATOM   11828 C  CA  . ARG B 1 650 ? 130.589 153.683 191.224 1.00 40.65  ? 650  ARG B CA  1 
ATOM   11829 C  C   . ARG B 1 650 ? 129.783 154.975 191.240 1.00 40.65  ? 650  ARG B C   1 
ATOM   11830 O  O   . ARG B 1 650 ? 129.341 155.438 190.183 1.00 40.65  ? 650  ARG B O   1 
ATOM   11831 C  CB  . ARG B 1 650 ? 129.684 152.486 191.509 1.00 40.65  ? 650  ARG B CB  1 
ATOM   11832 C  CG  . ARG B 1 650 ? 128.508 152.341 190.556 1.00 40.65  ? 650  ARG B CG  1 
ATOM   11833 C  CD  . ARG B 1 650 ? 128.962 152.023 189.140 1.00 40.65  ? 650  ARG B CD  1 
ATOM   11834 N  NE  . ARG B 1 650 ? 129.996 150.996 189.116 1.00 40.65  ? 650  ARG B NE  1 
ATOM   11835 C  CZ  . ARG B 1 650 ? 130.366 150.329 188.032 1.00 40.65  ? 650  ARG B CZ  1 
ATOM   11836 N  NH1 . ARG B 1 650 ? 129.777 150.527 186.866 1.00 40.65  ? 650  ARG B NH1 1 
ATOM   11837 N  NH2 . ARG B 1 650 ? 131.343 149.433 188.123 1.00 40.65  ? 650  ARG B NH2 1 
ATOM   11838 N  N   . ALA B 1 651 ? 129.586 155.574 192.416 1.00 42.37  ? 651  ALA B N   1 
ATOM   11839 C  CA  . ALA B 1 651 ? 128.805 156.800 192.513 1.00 42.37  ? 651  ALA B CA  1 
ATOM   11840 C  C   . ALA B 1 651 ? 129.525 158.004 191.926 1.00 42.37  ? 651  ALA B C   1 
ATOM   11841 O  O   . ALA B 1 651 ? 128.865 158.965 191.518 1.00 42.37  ? 651  ALA B O   1 
ATOM   11842 C  CB  . ALA B 1 651 ? 128.442 157.078 193.973 1.00 42.37  ? 651  ALA B CB  1 
ATOM   11843 N  N   . ALA B 1 652 ? 130.853 157.976 191.876 1.00 39.99  ? 652  ALA B N   1 
ATOM   11844 C  CA  . ALA B 1 652 ? 131.601 159.073 191.286 1.00 39.99  ? 652  ALA B CA  1 
ATOM   11845 C  C   . ALA B 1 652 ? 131.433 159.080 189.771 1.00 39.99  ? 652  ALA B C   1 
ATOM   11846 O  O   . ALA B 1 652 ? 131.111 158.064 189.149 1.00 39.99  ? 652  ALA B O   1 
ATOM   11847 C  CB  . ALA B 1 652 ? 133.082 158.969 191.647 1.00 39.99  ? 652  ALA B CB  1 
ATOM   11848 N  N   . ASP B 1 653 ? 131.650 160.255 189.176 1.00 42.27  ? 653  ASP B N   1 
ATOM   11849 C  CA  . ASP B 1 653 ? 131.618 160.348 187.722 1.00 42.27  ? 653  ASP B CA  1 
ATOM   11850 C  C   . ASP B 1 653 ? 132.687 159.470 187.089 1.00 42.27  ? 653  ASP B C   1 
ATOM   11851 O  O   . ASP B 1 653 ? 132.457 158.885 186.025 1.00 42.27  ? 653  ASP B O   1 
ATOM   11852 C  CB  . ASP B 1 653 ? 131.778 161.800 187.275 1.00 42.27  ? 653  ASP B CB  1 
ATOM   11853 C  CG  . ASP B 1 653 ? 130.454 162.528 187.188 1.00 42.27  ? 653  ASP B CG  1 
ATOM   11854 O  OD1 . ASP B 1 653 ? 129.439 161.876 186.864 1.00 42.27  ? 653  ASP B OD1 1 
ATOM   11855 O  OD2 . ASP B 1 653 ? 130.424 163.749 187.442 1.00 42.27  ? 653  ASP B OD2 1 
ATOM   11856 N  N   . ILE B 1 654 ? 133.855 159.363 187.718 1.00 37.40  ? 654  ILE B N   1 
ATOM   11857 C  CA  . ILE B 1 654 ? 134.864 158.399 187.294 1.00 37.40  ? 654  ILE B CA  1 
ATOM   11858 C  C   . ILE B 1 654 ? 135.530 157.797 188.525 1.00 37.40  ? 654  ILE B C   1 
ATOM   11859 O  O   . ILE B 1 654 ? 135.730 158.479 189.537 1.00 37.40  ? 654  ILE B O   1 
ATOM   11860 C  CB  . ILE B 1 654 ? 135.899 159.029 186.339 1.00 37.40  ? 654  ILE B CB  1 
ATOM   11861 C  CG1 . ILE B 1 654 ? 136.867 157.962 185.830 1.00 37.40  ? 654  ILE B CG1 1 
ATOM   11862 C  CG2 . ILE B 1 654 ? 136.640 160.166 187.007 1.00 37.40  ? 654  ILE B CG2 1 
ATOM   11863 C  CD1 . ILE B 1 654 ? 137.690 158.404 184.667 1.00 37.40  ? 654  ILE B CD1 1 
ATOM   11864 N  N   . GLY B 1 655 ? 135.842 156.506 188.445 1.00 34.74  ? 655  GLY B N   1 
ATOM   11865 C  CA  . GLY B 1 655 ? 136.504 155.788 189.518 1.00 34.74  ? 655  GLY B CA  1 
ATOM   11866 C  C   . GLY B 1 655 ? 137.868 155.289 189.067 1.00 34.74  ? 655  GLY B C   1 
ATOM   11867 O  O   . GLY B 1 655 ? 137.994 154.662 188.012 1.00 34.74  ? 655  GLY B O   1 
ATOM   11868 N  N   . ILE B 1 656 ? 138.878 155.578 189.881 1.00 32.05  ? 656  ILE B N   1 
ATOM   11869 C  CA  . ILE B 1 656 ? 140.260 155.213 189.602 1.00 32.05  ? 656  ILE B CA  1 
ATOM   11870 C  C   . ILE B 1 656 ? 140.748 154.310 190.725 1.00 32.05  ? 656  ILE B C   1 
ATOM   11871 O  O   . ILE B 1 656 ? 140.566 154.627 191.906 1.00 32.05  ? 656  ILE B O   1 
ATOM   11872 C  CB  . ILE B 1 656 ? 141.157 156.456 189.470 1.00 32.05  ? 656  ILE B CB  1 
ATOM   11873 C  CG1 . ILE B 1 656 ? 140.435 157.546 188.675 1.00 32.05  ? 656  ILE B CG1 1 
ATOM   11874 C  CG2 . ILE B 1 656 ? 142.467 156.094 188.801 1.00 32.05  ? 656  ILE B CG2 1 
ATOM   11875 C  CD1 . ILE B 1 656 ? 141.055 158.913 188.811 1.00 32.05  ? 656  ILE B CD1 1 
ATOM   11876 N  N   . SER B 1 657 ? 141.358 153.185 190.360 1.00 33.80  ? 657  SER B N   1 
ATOM   11877 C  CA  . SER B 1 657 ? 141.869 152.232 191.333 1.00 33.80  ? 657  SER B CA  1 
ATOM   11878 C  C   . SER B 1 657 ? 143.296 151.860 190.960 1.00 33.80  ? 657  SER B C   1 
ATOM   11879 O  O   . SER B 1 657 ? 143.867 152.380 189.999 1.00 33.80  ? 657  SER B O   1 
ATOM   11880 C  CB  . SER B 1 657 ? 140.982 150.987 191.413 1.00 33.80  ? 657  SER B CB  1 
ATOM   11881 O  OG  . SER B 1 657 ? 141.521 150.037 192.314 1.00 33.80  ? 657  SER B OG  1 
ATOM   11882 N  N   . VAL B 1 658 ? 143.869 150.939 191.729 1.00 36.63  ? 658  VAL B N   1 
ATOM   11883 C  CA  . VAL B 1 658 ? 145.241 150.491 191.540 1.00 36.63  ? 658  VAL B CA  1 
ATOM   11884 C  C   . VAL B 1 658 ? 145.215 149.018 191.159 1.00 36.63  ? 658  VAL B C   1 
ATOM   11885 O  O   . VAL B 1 658 ? 144.282 148.286 191.507 1.00 36.63  ? 658  VAL B O   1 
ATOM   11886 C  CB  . VAL B 1 658 ? 146.088 150.723 192.811 1.00 36.63  ? 658  VAL B CB  1 
ATOM   11887 C  CG1 . VAL B 1 658 ? 147.570 150.505 192.532 1.00 36.63  ? 658  VAL B CG1 1 
ATOM   11888 C  CG2 . VAL B 1 658 ? 145.840 152.117 193.361 1.00 36.63  ? 658  VAL B CG2 1 
ATOM   11889 N  N   . ASP B 1 659 ? 146.246 148.586 190.428 1.00 43.97  ? 659  ASP B N   1 
ATOM   11890 C  CA  . ASP B 1 659 ? 146.322 147.194 189.997 1.00 43.97  ? 659  ASP B CA  1 
ATOM   11891 C  C   . ASP B 1 659 ? 146.362 146.250 191.192 1.00 43.97  ? 659  ASP B C   1 
ATOM   11892 O  O   . ASP B 1 659 ? 145.688 145.214 191.204 1.00 43.97  ? 659  ASP B O   1 
ATOM   11893 C  CB  . ASP B 1 659 ? 147.548 146.990 189.107 1.00 43.97  ? 659  ASP B CB  1 
ATOM   11894 C  CG  . ASP B 1 659 ? 147.772 145.535 188.750 1.00 43.97  ? 659  ASP B CG  1 
ATOM   11895 O  OD1 . ASP B 1 659 ? 146.864 144.920 188.154 1.00 43.97  ? 659  ASP B OD1 1 
ATOM   11896 O  OD2 . ASP B 1 659 ? 148.858 145.006 189.067 1.00 43.97  ? 659  ASP B OD2 1 
ATOM   11897 N  N   . GLY B 1 660 ? 147.149 146.592 192.207 1.00 45.29  ? 660  GLY B N   1 
ATOM   11898 C  CA  . GLY B 1 660 ? 147.179 145.804 193.423 1.00 45.29  ? 660  GLY B CA  1 
ATOM   11899 C  C   . GLY B 1 660 ? 146.158 146.280 194.435 1.00 45.29  ? 660  GLY B C   1 
ATOM   11900 O  O   . GLY B 1 660 ? 146.410 147.232 195.180 1.00 45.29  ? 660  GLY B O   1 
ATOM   11901 N  N   . ALA B 1 661 ? 145.005 145.619 194.475 1.00 45.67  ? 661  ALA B N   1 
ATOM   11902 C  CA  . ALA B 1 661 ? 143.917 146.012 195.359 1.00 45.67  ? 661  ALA B CA  1 
ATOM   11903 C  C   . ALA B 1 661 ? 142.917 144.869 195.434 1.00 45.67  ? 661  ALA B C   1 
ATOM   11904 O  O   . ALA B 1 661 ? 143.063 143.843 194.765 1.00 45.67  ? 661  ALA B O   1 
ATOM   11905 C  CB  . ALA B 1 661 ? 143.237 147.297 194.877 1.00 45.67  ? 661  ALA B CB  1 
ATOM   11906 N  N   . VAL B 1 662 ? 141.892 145.059 196.268 1.00 45.63  ? 662  VAL B N   1 
ATOM   11907 C  CA  . VAL B 1 662 ? 140.823 144.077 196.348 1.00 45.63  ? 662  VAL B CA  1 
ATOM   11908 C  C   . VAL B 1 662 ? 140.048 144.067 195.034 1.00 45.63  ? 662  VAL B C   1 
ATOM   11909 O  O   . VAL B 1 662 ? 140.027 145.054 194.288 1.00 45.63  ? 662  VAL B O   1 
ATOM   11910 C  CB  . VAL B 1 662 ? 139.894 144.366 197.539 1.00 45.63  ? 662  VAL B CB  1 
ATOM   11911 C  CG1 . VAL B 1 662 ? 140.663 144.249 198.841 1.00 45.63  ? 662  VAL B CG1 1 
ATOM   11912 C  CG2 . VAL B 1 662 ? 139.286 145.747 197.411 1.00 45.63  ? 662  VAL B CG2 1 
ATOM   11913 N  N   . ASP B 1 663 ? 139.414 142.930 194.744 1.00 50.45  ? 663  ASP B N   1 
ATOM   11914 C  CA  . ASP B 1 663 ? 138.766 142.759 193.447 1.00 50.45  ? 663  ASP B CA  1 
ATOM   11915 C  C   . ASP B 1 663 ? 137.606 143.730 193.264 1.00 50.45  ? 663  ASP B C   1 
ATOM   11916 O  O   . ASP B 1 663 ? 137.435 144.302 192.181 1.00 50.45  ? 663  ASP B O   1 
ATOM   11917 C  CB  . ASP B 1 663 ? 138.293 141.316 193.288 1.00 50.45  ? 663  ASP B CB  1 
ATOM   11918 C  CG  . ASP B 1 663 ? 139.442 140.330 193.231 1.00 50.45  ? 663  ASP B CG  1 
ATOM   11919 O  OD1 . ASP B 1 663 ? 140.605 140.760 193.380 1.00 50.45  ? 663  ASP B OD1 1 
ATOM   11920 O  OD2 . ASP B 1 663 ? 139.182 139.125 193.034 1.00 50.45  ? 663  ASP B OD2 1 
ATOM   11921 N  N   . ILE B 1 664 ? 136.800 143.936 194.308 1.00 41.33  ? 664  ILE B N   1 
ATOM   11922 C  CA  . ILE B 1 664 ? 135.637 144.811 194.195 1.00 41.33  ? 664  ILE B CA  1 
ATOM   11923 C  C   . ILE B 1 664 ? 136.011 146.267 193.965 1.00 41.33  ? 664  ILE B C   1 
ATOM   11924 O  O   . ILE B 1 664 ? 135.184 147.035 193.461 1.00 41.33  ? 664  ILE B O   1 
ATOM   11925 C  CB  . ILE B 1 664 ? 134.739 144.689 195.443 1.00 41.33  ? 664  ILE B CB  1 
ATOM   11926 C  CG1 . ILE B 1 664 ? 133.304 145.113 195.121 1.00 41.33  ? 664  ILE B CG1 1 
ATOM   11927 C  CG2 . ILE B 1 664 ? 135.294 145.511 196.590 1.00 41.33  ? 664  ILE B CG2 1 
ATOM   11928 C  CD1 . ILE B 1 664 ? 132.606 144.210 194.132 1.00 41.33  ? 664  ILE B CD1 1 
ATOM   11929 N  N   . ALA B 1 665 ? 137.230 146.671 194.314 1.00 37.67  ? 665  ALA B N   1 
ATOM   11930 C  CA  . ALA B 1 665 ? 137.704 148.013 194.014 1.00 37.67  ? 665  ALA B CA  1 
ATOM   11931 C  C   . ALA B 1 665 ? 138.268 148.127 192.607 1.00 37.67  ? 665  ALA B C   1 
ATOM   11932 O  O   . ALA B 1 665 ? 138.506 149.242 192.138 1.00 37.67  ? 665  ALA B O   1 
ATOM   11933 C  CB  . ALA B 1 665 ? 138.762 148.446 195.033 1.00 37.67  ? 665  ALA B CB  1 
ATOM   11934 N  N   . ARG B 1 666 ? 138.476 147.003 191.924 1.00 41.87  ? 666  ARG B N   1 
ATOM   11935 C  CA  . ARG B 1 666 ? 138.917 146.989 190.535 1.00 41.87  ? 666  ARG B CA  1 
ATOM   11936 C  C   . ARG B 1 666 ? 137.757 146.780 189.572 1.00 41.87  ? 666  ARG B C   1 
ATOM   11937 O  O   . ARG B 1 666 ? 137.737 147.363 188.485 1.00 41.87  ? 666  ARG B O   1 
ATOM   11938 C  CB  . ARG B 1 666 ? 139.971 145.896 190.331 1.00 41.87  ? 666  ARG B CB  1 
ATOM   11939 C  CG  . ARG B 1 666 ? 141.277 146.154 191.058 1.00 41.87  ? 666  ARG B CG  1 
ATOM   11940 C  CD  . ARG B 1 666 ? 142.138 144.904 191.093 1.00 41.87  ? 666  ARG B CD  1 
ATOM   11941 N  NE  . ARG B 1 666 ? 141.995 144.110 189.880 1.00 41.87  ? 666  ARG B NE  1 
ATOM   11942 C  CZ  . ARG B 1 666 ? 142.986 143.836 189.043 1.00 41.87  ? 666  ARG B CZ  1 
ATOM   11943 N  NH1 . ARG B 1 666 ? 144.214 144.279 189.259 1.00 41.87  ? 666  ARG B NH1 1 
ATOM   11944 N  NH2 . ARG B 1 666 ? 142.739 143.100 187.964 1.00 41.87  ? 666  ARG B NH2 1 
ATOM   11945 N  N   . GLU B 1 667 ? 136.786 145.948 189.955 1.00 41.03  ? 667  GLU B N   1 
ATOM   11946 C  CA  . GLU B 1 667 ? 135.597 145.765 189.131 1.00 41.03  ? 667  GLU B CA  1 
ATOM   11947 C  C   . GLU B 1 667 ? 134.786 147.050 189.046 1.00 41.03  ? 667  GLU B C   1 
ATOM   11948 O  O   . GLU B 1 667 ? 134.253 147.390 187.984 1.00 41.03  ? 667  GLU B O   1 
ATOM   11949 C  CB  . GLU B 1 667 ? 134.742 144.630 189.694 1.00 41.03  ? 667  GLU B CB  1 
ATOM   11950 C  CG  . GLU B 1 667 ? 133.781 144.023 188.690 1.00 41.03  ? 667  GLU B CG  1 
ATOM   11951 C  CD  . GLU B 1 667 ? 134.446 142.988 187.806 1.00 41.03  ? 667  GLU B CD  1 
ATOM   11952 O  OE1 . GLU B 1 667 ? 135.626 142.663 188.053 1.00 41.03  ? 667  GLU B OE1 1 
ATOM   11953 O  OE2 . GLU B 1 667 ? 133.790 142.500 186.862 1.00 41.03  ? 667  GLU B OE2 1 
ATOM   11954 N  N   . ALA B 1 668 ? 134.680 147.777 190.160 1.00 36.49  ? 668  ALA B N   1 
ATOM   11955 C  CA  . ALA B 1 668 ? 133.887 148.998 190.197 1.00 36.49  ? 668  ALA B CA  1 
ATOM   11956 C  C   . ALA B 1 668 ? 134.601 150.191 189.580 1.00 36.49  ? 668  ALA B C   1 
ATOM   11957 O  O   . ALA B 1 668 ? 133.950 151.198 189.285 1.00 36.49  ? 668  ALA B O   1 
ATOM   11958 C  CB  . ALA B 1 668 ? 133.499 149.328 191.639 1.00 36.49  ? 668  ALA B CB  1 
ATOM   11959 N  N   . ALA B 1 669 ? 135.911 150.107 189.379 1.00 33.72  ? 669  ALA B N   1 
ATOM   11960 C  CA  . ALA B 1 669 ? 136.659 151.238 188.859 1.00 33.72  ? 669  ALA B CA  1 
ATOM   11961 C  C   . ALA B 1 669 ? 136.541 151.322 187.341 1.00 33.72  ? 669  ALA B C   1 
ATOM   11962 O  O   . ALA B 1 669 ? 136.228 150.345 186.656 1.00 33.72  ? 669  ALA B O   1 
ATOM   11963 C  CB  . ALA B 1 669 ? 138.130 151.141 189.260 1.00 33.72  ? 669  ALA B CB  1 
ATOM   11964 N  N   . ASP B 1 670 ? 136.801 152.519 186.819 1.00 34.17  ? 670  ASP B N   1 
ATOM   11965 C  CA  . ASP B 1 670 ? 136.845 152.750 185.382 1.00 34.17  ? 670  ASP B CA  1 
ATOM   11966 C  C   . ASP B 1 670 ? 138.261 152.913 184.851 1.00 34.17  ? 670  ASP B C   1 
ATOM   11967 O  O   . ASP B 1 670 ? 138.500 152.655 183.667 1.00 34.17  ? 670  ASP B O   1 
ATOM   11968 C  CB  . ASP B 1 670 ? 136.028 153.994 185.019 1.00 34.17  ? 670  ASP B CB  1 
ATOM   11969 C  CG  . ASP B 1 670 ? 134.544 153.796 185.235 1.00 34.17  ? 670  ASP B CG  1 
ATOM   11970 O  OD1 . ASP B 1 670 ? 134.075 152.644 185.125 1.00 34.17  ? 670  ASP B OD1 1 
ATOM   11971 O  OD2 . ASP B 1 670 ? 133.846 154.792 185.518 1.00 34.17  ? 670  ASP B OD2 1 
ATOM   11972 N  N   . ILE B 1 671 ? 139.198 153.336 185.695 1.00 29.63  ? 671  ILE B N   1 
ATOM   11973 C  CA  . ILE B 1 671 ? 140.601 153.482 185.330 1.00 29.63  ? 671  ILE B CA  1 
ATOM   11974 C  C   . ILE B 1 671 ? 141.431 152.686 186.325 1.00 29.63  ? 671  ILE B C   1 
ATOM   11975 O  O   . ILE B 1 671 ? 141.123 152.671 187.522 1.00 29.63  ? 671  ILE B O   1 
ATOM   11976 C  CB  . ILE B 1 671 ? 141.031 154.964 185.319 1.00 29.63  ? 671  ILE B CB  1 
ATOM   11977 C  CG1 . ILE B 1 671 ? 140.149 155.769 184.368 1.00 29.63  ? 671  ILE B CG1 1 
ATOM   11978 C  CG2 . ILE B 1 671 ? 142.486 155.100 184.918 1.00 29.63  ? 671  ILE B CG2 1 
ATOM   11979 C  CD1 . ILE B 1 671 ? 140.301 155.376 182.925 1.00 29.63  ? 671  ILE B CD1 1 
ATOM   11980 N  N   . ILE B 1 672 ? 142.468 152.010 185.837 1.00 30.59  ? 672  ILE B N   1 
ATOM   11981 C  CA  . ILE B 1 672 ? 143.353 151.219 186.686 1.00 30.59  ? 672  ILE B CA  1 
ATOM   11982 C  C   . ILE B 1 672 ? 144.773 151.726 186.483 1.00 30.59  ? 672  ILE B C   1 
ATOM   11983 O  O   . ILE B 1 672 ? 145.324 151.624 185.381 1.00 30.59  ? 672  ILE B O   1 
ATOM   11984 C  CB  . ILE B 1 672 ? 143.255 149.719 186.379 1.00 30.59  ? 672  ILE B CB  1 
ATOM   11985 C  CG1 . ILE B 1 672 ? 141.823 149.224 186.586 1.00 30.59  ? 672  ILE B CG1 1 
ATOM   11986 C  CG2 . ILE B 1 672 ? 144.221 148.936 187.252 1.00 30.59  ? 672  ILE B CG2 1 
ATOM   11987 C  CD1 . ILE B 1 672 ? 141.380 149.221 188.029 1.00 30.59  ? 672  ILE B CD1 1 
ATOM   11988 N  N   . LEU B 1 673 ? 145.372 152.264 187.539 1.00 31.34  ? 673  LEU B N   1 
ATOM   11989 C  CA  . LEU B 1 673 ? 146.765 152.674 187.481 1.00 31.34  ? 673  LEU B CA  1 
ATOM   11990 C  C   . LEU B 1 673 ? 147.658 151.513 187.896 1.00 31.34  ? 673  LEU B C   1 
ATOM   11991 O  O   . LEU B 1 673 ? 147.414 150.858 188.913 1.00 31.34  ? 673  LEU B O   1 
ATOM   11992 C  CB  . LEU B 1 673 ? 147.011 153.879 188.387 1.00 31.34  ? 673  LEU B CB  1 
ATOM   11993 C  CG  . LEU B 1 673 ? 145.948 154.978 188.361 1.00 31.34  ? 673  LEU B CG  1 
ATOM   11994 C  CD1 . LEU B 1 673 ? 146.330 156.114 189.293 1.00 31.34  ? 673  LEU B CD1 1 
ATOM   11995 C  CD2 . LEU B 1 673 ? 145.740 155.492 186.948 1.00 31.34  ? 673  LEU B CD2 1 
ATOM   11996 N  N   . LEU B 1 674 ? 148.693 151.253 187.095 1.00 34.05  ? 674  LEU B N   1 
ATOM   11997 C  CA  . LEU B 1 674 ? 149.594 150.150 187.406 1.00 34.05  ? 674  LEU B CA  1 
ATOM   11998 C  C   . LEU B 1 674 ? 150.357 150.396 188.702 1.00 34.05  ? 674  LEU B C   1 
ATOM   11999 O  O   . LEU B 1 674 ? 150.750 149.440 189.378 1.00 34.05  ? 674  LEU B O   1 
ATOM   12000 C  CB  . LEU B 1 674 ? 150.560 149.916 186.246 1.00 34.05  ? 674  LEU B CB  1 
ATOM   12001 C  CG  . LEU B 1 674 ? 149.903 149.461 184.941 1.00 34.05  ? 674  LEU B CG  1 
ATOM   12002 C  CD1 . LEU B 1 674 ? 150.946 149.194 183.868 1.00 34.05  ? 674  LEU B CD1 1 
ATOM   12003 C  CD2 . LEU B 1 674 ? 149.046 148.229 185.177 1.00 34.05  ? 674  LEU B CD2 1 
ATOM   12004 N  N   . GLU B 1 675 ? 150.573 151.658 189.063 1.00 37.76  ? 675  GLU B N   1 
ATOM   12005 C  CA  . GLU B 1 675 ? 151.143 152.016 190.351 1.00 37.76  ? 675  GLU B CA  1 
ATOM   12006 C  C   . GLU B 1 675 ? 150.344 153.164 190.950 1.00 37.76  ? 675  GLU B C   1 
ATOM   12007 O  O   . GLU B 1 675 ? 149.783 153.994 190.230 1.00 37.76  ? 675  GLU B O   1 
ATOM   12008 C  CB  . GLU B 1 675 ? 152.625 152.403 190.237 1.00 37.76  ? 675  GLU B CB  1 
ATOM   12009 C  CG  . GLU B 1 675 ? 152.884 153.709 189.512 1.00 37.76  ? 675  GLU B CG  1 
ATOM   12010 C  CD  . GLU B 1 675 ? 154.356 154.066 189.475 1.00 37.76  ? 675  GLU B CD  1 
ATOM   12011 O  OE1 . GLU B 1 675 ? 155.171 153.275 189.993 1.00 37.76  ? 675  GLU B OE1 1 
ATOM   12012 O  OE2 . GLU B 1 675 ? 154.699 155.136 188.929 1.00 37.76  ? 675  GLU B OE2 1 
ATOM   12013 N  N   . LYS B 1 676 ? 150.290 153.197 192.279 1.00 36.67  ? 676  LYS B N   1 
ATOM   12014 C  CA  . LYS B 1 676 ? 149.495 154.188 193.002 1.00 36.67  ? 676  LYS B CA  1 
ATOM   12015 C  C   . LYS B 1 676 ? 150.330 155.449 193.180 1.00 36.67  ? 676  LYS B C   1 
ATOM   12016 O  O   . LYS B 1 676 ? 151.073 155.599 194.151 1.00 36.67  ? 676  LYS B O   1 
ATOM   12017 C  CB  . LYS B 1 676 ? 149.036 153.627 194.341 1.00 36.67  ? 676  LYS B CB  1 
ATOM   12018 C  CG  . LYS B 1 676 ? 148.072 154.525 195.092 1.00 36.67  ? 676  LYS B CG  1 
ATOM   12019 C  CD  . LYS B 1 676 ? 147.444 153.792 196.266 1.00 36.67  ? 676  LYS B CD  1 
ATOM   12020 C  CE  . LYS B 1 676 ? 146.047 154.312 196.562 1.00 36.67  ? 676  LYS B CE  1 
ATOM   12021 N  NZ  . LYS B 1 676 ? 145.541 153.837 197.879 1.00 36.67  ? 676  LYS B NZ  1 
ATOM   12022 N  N   . SER B 1 677 ? 150.203 156.372 192.230 1.00 40.20  ? 677  SER B N   1 
ATOM   12023 C  CA  . SER B 1 677 ? 150.944 157.624 192.273 1.00 40.20  ? 677  SER B CA  1 
ATOM   12024 C  C   . SER B 1 677 ? 150.105 158.725 191.643 1.00 40.20  ? 677  SER B C   1 
ATOM   12025 O  O   . SER B 1 677 ? 149.380 158.484 190.675 1.00 40.20  ? 677  SER B O   1 
ATOM   12026 C  CB  . SER B 1 677 ? 152.288 157.503 191.548 1.00 40.20  ? 677  SER B CB  1 
ATOM   12027 O  OG  . SER B 1 677 ? 152.995 158.730 191.580 1.00 40.20  ? 677  SER B OG  1 
ATOM   12028 N  N   . LEU B 1 678 ? 150.210 159.933 192.200 1.00 37.72  ? 678  LEU B N   1 
ATOM   12029 C  CA  . LEU B 1 678 ? 149.454 161.064 191.675 1.00 37.72  ? 678  LEU B CA  1 
ATOM   12030 C  C   . LEU B 1 678 ? 150.066 161.627 190.398 1.00 37.72  ? 678  LEU B C   1 
ATOM   12031 O  O   . LEU B 1 678 ? 149.336 162.150 189.549 1.00 37.72  ? 678  LEU B O   1 
ATOM   12032 C  CB  . LEU B 1 678 ? 149.347 162.161 192.734 1.00 37.72  ? 678  LEU B CB  1 
ATOM   12033 C  CG  . LEU B 1 678 ? 148.378 161.904 193.888 1.00 37.72  ? 678  LEU B CG  1 
ATOM   12034 C  CD1 . LEU B 1 678 ? 148.338 163.098 194.823 1.00 37.72  ? 678  LEU B CD1 1 
ATOM   12035 C  CD2 . LEU B 1 678 ? 146.991 161.595 193.358 1.00 37.72  ? 678  LEU B CD2 1 
ATOM   12036 N  N   . MET B 1 679 ? 151.390 161.544 190.249 1.00 45.13  ? 679  MET B N   1 
ATOM   12037 C  CA  . MET B 1 679 ? 152.031 162.048 189.037 1.00 45.13  ? 679  MET B CA  1 
ATOM   12038 C  C   . MET B 1 679 ? 151.567 161.280 187.806 1.00 45.13  ? 679  MET B C   1 
ATOM   12039 O  O   . MET B 1 679 ? 151.303 161.878 186.753 1.00 45.13  ? 679  MET B O   1 
ATOM   12040 C  CB  . MET B 1 679 ? 153.551 161.967 189.180 1.00 45.13  ? 679  MET B CB  1 
ATOM   12041 C  CG  . MET B 1 679 ? 154.319 162.482 187.976 1.00 45.13  ? 679  MET B CG  1 
ATOM   12042 S  SD  . MET B 1 679 ? 153.852 164.159 187.509 1.00 45.13  ? 679  MET B SD  1 
ATOM   12043 C  CE  . MET B 1 679 ? 154.668 165.101 188.795 1.00 45.13  ? 679  MET B CE  1 
ATOM   12044 N  N   . VAL B 1 680 ? 151.469 159.954 187.921 1.00 39.72  ? 680  VAL B N   1 
ATOM   12045 C  CA  . VAL B 1 680 ? 150.960 159.140 186.822 1.00 39.72  ? 680  VAL B CA  1 
ATOM   12046 C  C   . VAL B 1 680 ? 149.537 159.553 186.475 1.00 39.72  ? 680  VAL B C   1 
ATOM   12047 O  O   . VAL B 1 680 ? 149.171 159.655 185.298 1.00 39.72  ? 680  VAL B O   1 
ATOM   12048 C  CB  . VAL B 1 680 ? 151.045 157.647 187.187 1.00 39.72  ? 680  VAL B CB  1 
ATOM   12049 C  CG1 . VAL B 1 680 ? 150.442 156.797 186.091 1.00 39.72  ? 680  VAL B CG1 1 
ATOM   12050 C  CG2 . VAL B 1 680 ? 152.488 157.249 187.442 1.00 39.72  ? 680  VAL B CG2 1 
ATOM   12051 N  N   . LEU B 1 681 ? 148.714 159.802 187.497 1.00 39.84  ? 681  LEU B N   1 
ATOM   12052 C  CA  . LEU B 1 681 ? 147.339 160.230 187.264 1.00 39.84  ? 681  LEU B CA  1 
ATOM   12053 C  C   . LEU B 1 681 ? 147.290 161.569 186.539 1.00 39.84  ? 681  LEU B C   1 
ATOM   12054 O  O   . LEU B 1 681 ? 146.479 161.757 185.626 1.00 39.84  ? 681  LEU B O   1 
ATOM   12055 C  CB  . LEU B 1 681 ? 146.592 160.305 188.595 1.00 39.84  ? 681  LEU B CB  1 
ATOM   12056 C  CG  . LEU B 1 681 ? 145.083 160.543 188.584 1.00 39.84  ? 681  LEU B CG  1 
ATOM   12057 C  CD1 . LEU B 1 681 ? 144.449 159.777 189.727 1.00 39.84  ? 681  LEU B CD1 1 
ATOM   12058 C  CD2 . LEU B 1 681 ? 144.762 162.023 188.704 1.00 39.84  ? 681  LEU B CD2 1 
ATOM   12059 N  N   . GLU B 1 682 ? 148.144 162.514 186.935 1.00 42.52  ? 682  GLU B N   1 
ATOM   12060 C  CA  . GLU B 1 682 ? 148.156 163.825 186.291 1.00 42.52  ? 682  GLU B CA  1 
ATOM   12061 C  C   . GLU B 1 682 ? 148.585 163.721 184.830 1.00 42.52  ? 682  GLU B C   1 
ATOM   12062 O  O   . GLU B 1 682 ? 147.973 164.335 183.943 1.00 42.52  ? 682  GLU B O   1 
ATOM   12063 C  CB  . GLU B 1 682 ? 149.077 164.771 187.061 1.00 42.52  ? 682  GLU B CB  1 
ATOM   12064 C  CG  . GLU B 1 682 ? 149.008 166.217 186.610 1.00 42.52  ? 682  GLU B CG  1 
ATOM   12065 C  CD  . GLU B 1 682 ? 150.094 166.562 185.612 1.00 42.52  ? 682  GLU B CD  1 
ATOM   12066 O  OE1 . GLU B 1 682 ? 151.176 165.942 185.674 1.00 42.52  ? 682  GLU B OE1 1 
ATOM   12067 O  OE2 . GLU B 1 682 ? 149.865 167.452 184.767 1.00 42.52  ? 682  GLU B OE2 1 
ATOM   12068 N  N   . GLU B 1 683 ? 149.639 162.946 184.560 1.00 44.48  ? 683  GLU B N   1 
ATOM   12069 C  CA  . GLU B 1 683 ? 150.079 162.763 183.180 1.00 44.48  ? 683  GLU B CA  1 
ATOM   12070 C  C   . GLU B 1 683 ? 149.002 162.079 182.347 1.00 44.48  ? 683  GLU B C   1 
ATOM   12071 O  O   . GLU B 1 683 ? 148.772 162.447 181.187 1.00 44.48  ? 683  GLU B O   1 
ATOM   12072 C  CB  . GLU B 1 683 ? 151.382 161.966 183.142 1.00 44.48  ? 683  GLU B CB  1 
ATOM   12073 C  CG  . GLU B 1 683 ? 152.521 162.611 183.912 1.00 44.48  ? 683  GLU B CG  1 
ATOM   12074 C  CD  . GLU B 1 683 ? 153.862 161.968 183.621 1.00 44.48  ? 683  GLU B CD  1 
ATOM   12075 O  OE1 . GLU B 1 683 ? 153.952 161.193 182.646 1.00 44.48  ? 683  GLU B OE1 1 
ATOM   12076 O  OE2 . GLU B 1 683 ? 154.826 162.239 184.366 1.00 44.48  ? 683  GLU B OE2 1 
ATOM   12077 N  N   . GLY B 1 684 ? 148.329 161.082 182.924 1.00 41.12  ? 684  GLY B N   1 
ATOM   12078 C  CA  . GLY B 1 684 ? 147.237 160.437 182.218 1.00 41.12  ? 684  GLY B CA  1 
ATOM   12079 C  C   . GLY B 1 684 ? 146.090 161.384 181.932 1.00 41.12  ? 684  GLY B C   1 
ATOM   12080 O  O   . GLY B 1 684 ? 145.470 161.317 180.870 1.00 41.12  ? 684  GLY B O   1 
ATOM   12081 N  N   . VAL B 1 685 ? 145.782 162.270 182.881 1.00 39.51  ? 685  VAL B N   1 
ATOM   12082 C  CA  . VAL B 1 685 ? 144.724 163.254 182.668 1.00 39.51  ? 685  VAL B CA  1 
ATOM   12083 C  C   . VAL B 1 685 ? 145.091 164.173 181.512 1.00 39.51  ? 685  VAL B C   1 
ATOM   12084 O  O   . VAL B 1 685 ? 144.263 164.470 180.642 1.00 39.51  ? 685  VAL B O   1 
ATOM   12085 C  CB  . VAL B 1 685 ? 144.457 164.048 183.960 1.00 39.51  ? 685  VAL B CB  1 
ATOM   12086 C  CG1 . VAL B 1 685 ? 143.747 165.352 183.648 1.00 39.51  ? 685  VAL B CG1 1 
ATOM   12087 C  CG2 . VAL B 1 685 ? 143.638 163.220 184.933 1.00 39.51  ? 685  VAL B CG2 1 
ATOM   12088 N  N   . ILE B 1 686 ? 146.346 164.624 181.478 1.00 40.63  ? 686  ILE B N   1 
ATOM   12089 C  CA  . ILE B 1 686 ? 146.789 165.489 180.387 1.00 40.63  ? 686  ILE B CA  1 
ATOM   12090 C  C   . ILE B 1 686 ? 146.668 164.769 179.048 1.00 40.63  ? 686  ILE B C   1 
ATOM   12091 O  O   . ILE B 1 686 ? 146.151 165.324 178.066 1.00 40.63  ? 686  ILE B O   1 
ATOM   12092 C  CB  . ILE B 1 686 ? 148.228 165.976 180.643 1.00 40.63  ? 686  ILE B CB  1 
ATOM   12093 C  CG1 . ILE B 1 686 ? 148.264 166.926 181.842 1.00 40.63  ? 686  ILE B CG1 1 
ATOM   12094 C  CG2 . ILE B 1 686 ? 148.792 166.649 179.405 1.00 40.63  ? 686  ILE B CG2 1 
ATOM   12095 C  CD1 . ILE B 1 686 ? 147.292 168.080 181.736 1.00 40.63  ? 686  ILE B CD1 1 
ATOM   12096 N  N   . GLU B 1 687 ? 147.125 163.516 178.988 1.00 40.23  ? 687  GLU B N   1 
ATOM   12097 C  CA  . GLU B 1 687 ? 147.084 162.791 177.723 1.00 40.23  ? 687  GLU B CA  1 
ATOM   12098 C  C   . GLU B 1 687 ? 145.653 162.487 177.287 1.00 40.23  ? 687  GLU B C   1 
ATOM   12099 O  O   . GLU B 1 687 ? 145.353 162.526 176.088 1.00 40.23  ? 687  GLU B O   1 
ATOM   12100 C  CB  . GLU B 1 687 ? 147.899 161.503 177.831 1.00 40.23  ? 687  GLU B CB  1 
ATOM   12101 C  CG  . GLU B 1 687 ? 148.179 160.827 176.499 1.00 40.23  ? 687  GLU B CG  1 
ATOM   12102 C  CD  . GLU B 1 687 ? 147.031 159.964 176.029 1.00 40.23  ? 687  GLU B CD  1 
ATOM   12103 O  OE1 . GLU B 1 687 ? 146.282 159.460 176.887 1.00 40.23  ? 687  GLU B OE1 1 
ATOM   12104 O  OE2 . GLU B 1 687 ? 146.875 159.793 174.802 1.00 40.23  ? 687  GLU B OE2 1 
ATOM   12105 N  N   . GLY B 1 688 ? 144.757 162.190 178.232 1.00 40.24  ? 688  GLY B N   1 
ATOM   12106 C  CA  . GLY B 1 688 ? 143.358 162.006 177.891 1.00 40.24  ? 688  GLY B CA  1 
ATOM   12107 C  C   . GLY B 1 688 ? 142.689 163.271 177.402 1.00 40.24  ? 688  GLY B C   1 
ATOM   12108 O  O   . GLY B 1 688 ? 141.853 163.220 176.491 1.00 40.24  ? 688  GLY B O   1 
ATOM   12109 N  N   . ARG B 1 689 ? 143.037 164.418 177.993 1.00 42.82  ? 689  ARG B N   1 
ATOM   12110 C  CA  . ARG B 1 689 ? 142.561 165.689 177.460 1.00 42.82  ? 689  ARG B CA  1 
ATOM   12111 C  C   . ARG B 1 689 ? 143.036 165.881 176.027 1.00 42.82  ? 689  ARG B C   1 
ATOM   12112 O  O   . ARG B 1 689 ? 142.270 166.329 175.165 1.00 42.82  ? 689  ARG B O   1 
ATOM   12113 C  CB  . ARG B 1 689 ? 143.037 166.846 178.338 1.00 42.82  ? 689  ARG B CB  1 
ATOM   12114 C  CG  . ARG B 1 689 ? 142.480 166.845 179.751 1.00 42.82  ? 689  ARG B CG  1 
ATOM   12115 C  CD  . ARG B 1 689 ? 142.725 168.180 180.435 1.00 42.82  ? 689  ARG B CD  1 
ATOM   12116 N  NE  . ARG B 1 689 ? 142.013 168.289 181.702 1.00 42.82  ? 689  ARG B NE  1 
ATOM   12117 C  CZ  . ARG B 1 689 ? 142.468 168.947 182.759 1.00 42.82  ? 689  ARG B CZ  1 
ATOM   12118 N  NH1 . ARG B 1 689 ? 143.634 169.571 182.735 1.00 42.82  ? 689  ARG B NH1 1 
ATOM   12119 N  NH2 . ARG B 1 689 ? 141.738 168.975 183.870 1.00 42.82  ? 689  ARG B NH2 1 
ATOM   12120 N  N   . ARG B 1 690 ? 144.297 165.535 175.755 1.00 44.79  ? 690  ARG B N   1 
ATOM   12121 C  CA  . ARG B 1 690 ? 144.805 165.619 174.388 1.00 44.79  ? 690  ARG B CA  1 
ATOM   12122 C  C   . ARG B 1 690 ? 144.016 164.717 173.446 1.00 44.79  ? 690  ARG B C   1 
ATOM   12123 O  O   . ARG B 1 690 ? 143.673 165.121 172.328 1.00 44.79  ? 690  ARG B O   1 
ATOM   12124 C  CB  . ARG B 1 690 ? 146.287 165.248 174.353 1.00 44.79  ? 690  ARG B CB  1 
ATOM   12125 C  CG  . ARG B 1 690 ? 147.229 166.374 174.730 1.00 44.79  ? 690  ARG B CG  1 
ATOM   12126 C  CD  . ARG B 1 690 ? 148.659 166.022 174.360 1.00 44.79  ? 690  ARG B CD  1 
ATOM   12127 N  NE  . ARG B 1 690 ? 149.627 166.618 175.273 1.00 44.79  ? 690  ARG B NE  1 
ATOM   12128 C  CZ  . ARG B 1 690 ? 150.660 165.970 175.793 1.00 44.79  ? 690  ARG B CZ  1 
ATOM   12129 N  NH1 . ARG B 1 690 ? 150.890 164.697 175.513 1.00 44.79  ? 690  ARG B NH1 1 
ATOM   12130 N  NH2 . ARG B 1 690 ? 151.483 166.614 176.616 1.00 44.79  ? 690  ARG B NH2 1 
ATOM   12131 N  N   . THR B 1 691 ? 143.722 163.491 173.880 1.00 39.29  ? 691  THR B N   1 
ATOM   12132 C  CA  . THR B 1 691 ? 142.987 162.552 173.034 1.00 39.29  ? 691  THR B CA  1 
ATOM   12133 C  C   . THR B 1 691 ? 141.583 163.063 172.724 1.00 39.29  ? 691  THR B C   1 
ATOM   12134 O  O   . THR B 1 691 ? 141.126 163.012 171.573 1.00 39.29  ? 691  THR B O   1 
ATOM   12135 C  CB  . THR B 1 691 ? 142.920 161.183 173.710 1.00 39.29  ? 691  THR B CB  1 
ATOM   12136 O  OG1 . THR B 1 691 ? 144.242 160.649 173.845 1.00 39.29  ? 691  THR B OG1 1 
ATOM   12137 C  CG2 . THR B 1 691 ? 142.074 160.226 172.889 1.00 39.29  ? 691  THR B CG2 1 
ATOM   12138 N  N   . PHE B 1 692 ? 140.878 163.556 173.744 1.00 40.20  ? 692  PHE B N   1 
ATOM   12139 C  CA  . PHE B 1 692 ? 139.528 164.057 173.510 1.00 40.20  ? 692  PHE B CA  1 
ATOM   12140 C  C   . PHE B 1 692 ? 139.548 165.302 172.634 1.00 40.20  ? 692  PHE B C   1 
ATOM   12141 O  O   . PHE B 1 692 ? 138.658 165.492 171.793 1.00 40.20  ? 692  PHE B O   1 
ATOM   12142 C  CB  . PHE B 1 692 ? 138.824 164.342 174.834 1.00 40.20  ? 692  PHE B CB  1 
ATOM   12143 C  CG  . PHE B 1 692 ? 137.331 164.411 174.715 1.00 40.20  ? 692  PHE B CG  1 
ATOM   12144 C  CD1 . PHE B 1 692 ? 136.596 163.277 174.418 1.00 40.20  ? 692  PHE B CD1 1 
ATOM   12145 C  CD2 . PHE B 1 692 ? 136.664 165.611 174.885 1.00 40.20  ? 692  PHE B CD2 1 
ATOM   12146 C  CE1 . PHE B 1 692 ? 135.222 163.336 174.303 1.00 40.20  ? 692  PHE B CE1 1 
ATOM   12147 C  CE2 . PHE B 1 692 ? 135.290 165.677 174.771 1.00 40.20  ? 692  PHE B CE2 1 
ATOM   12148 C  CZ  . PHE B 1 692 ? 134.568 164.538 174.480 1.00 40.20  ? 692  PHE B CZ  1 
ATOM   12149 N  N   . ALA B 1 693 ? 140.555 166.162 172.812 1.00 41.23  ? 693  ALA B N   1 
ATOM   12150 C  CA  . ALA B 1 693 ? 140.698 167.315 171.932 1.00 41.23  ? 693  ALA B CA  1 
ATOM   12151 C  C   . ALA B 1 693 ? 140.924 166.876 170.493 1.00 41.23  ? 693  ALA B C   1 
ATOM   12152 O  O   . ALA B 1 693 ? 140.372 167.472 169.561 1.00 41.23  ? 693  ALA B O   1 
ATOM   12153 C  CB  . ALA B 1 693 ? 141.845 168.203 172.412 1.00 41.23  ? 693  ALA B CB  1 
ATOM   12154 N  N   . ASN B 1 694 ? 141.732 165.832 170.292 1.00 44.28  ? 694  ASN B N   1 
ATOM   12155 C  CA  . ASN B 1 694 ? 141.948 165.307 168.948 1.00 44.28  ? 694  ASN B CA  1 
ATOM   12156 C  C   . ASN B 1 694 ? 140.648 164.807 168.336 1.00 44.28  ? 694  ASN B C   1 
ATOM   12157 O  O   . ASN B 1 694 ? 140.361 165.072 167.162 1.00 44.28  ? 694  ASN B O   1 
ATOM   12158 C  CB  . ASN B 1 694 ? 142.981 164.182 168.982 1.00 44.28  ? 694  ASN B CB  1 
ATOM   12159 C  CG  . ASN B 1 694 ? 144.391 164.682 168.785 1.00 44.28  ? 694  ASN B CG  1 
ATOM   12160 O  OD1 . ASN B 1 694 ? 144.604 165.802 168.325 1.00 44.28  ? 694  ASN B OD1 1 
ATOM   12161 N  ND2 . ASN B 1 694 ? 145.366 163.851 169.131 1.00 44.28  ? 694  ASN B ND2 1 
ATOM   12162 N  N   . MET B 1 695 ? 139.851 164.075 169.116 1.00 38.32  ? 695  MET B N   1 
ATOM   12163 C  CA  . MET B 1 695 ? 138.582 163.565 168.603 1.00 38.32  ? 695  MET B CA  1 
ATOM   12164 C  C   . MET B 1 695 ? 137.647 164.707 168.215 1.00 38.32  ? 695  MET B C   1 
ATOM   12165 O  O   . MET B 1 695 ? 137.029 164.692 167.138 1.00 38.32  ? 695  MET B O   1 
ATOM   12166 C  CB  . MET B 1 695 ? 137.925 162.664 169.647 1.00 38.32  ? 695  MET B CB  1 
ATOM   12167 C  CG  . MET B 1 695 ? 136.805 161.799 169.108 1.00 38.32  ? 695  MET B CG  1 
ATOM   12168 S  SD  . MET B 1 695 ? 135.696 161.250 170.415 1.00 38.32  ? 695  MET B SD  1 
ATOM   12169 C  CE  . MET B 1 695 ? 134.650 162.691 170.592 1.00 38.32  ? 695  MET B CE  1 
ATOM   12170 N  N   . LEU B 1 696 ? 137.538 165.715 169.085 1.00 40.44  ? 696  LEU B N   1 
ATOM   12171 C  CA  . LEU B 1 696 ? 136.673 166.851 168.792 1.00 40.44  ? 696  LEU B CA  1 
ATOM   12172 C  C   . LEU B 1 696 ? 137.149 167.599 167.554 1.00 40.44  ? 696  LEU B C   1 
ATOM   12173 O  O   . LEU B 1 696 ? 136.336 168.018 166.723 1.00 40.44  ? 696  LEU B O   1 
ATOM   12174 C  CB  . LEU B 1 696 ? 136.608 167.790 169.996 1.00 40.44  ? 696  LEU B CB  1 
ATOM   12175 C  CG  . LEU B 1 696 ? 135.806 167.281 171.194 1.00 40.44  ? 696  LEU B CG  1 
ATOM   12176 C  CD1 . LEU B 1 696 ? 135.777 168.319 172.301 1.00 40.44  ? 696  LEU B CD1 1 
ATOM   12177 C  CD2 . LEU B 1 696 ? 134.396 166.910 170.768 1.00 40.44  ? 696  LEU B CD2 1 
ATOM   12178 N  N   . LYS B 1 697 ? 138.465 167.775 167.416 1.00 46.39  ? 697  LYS B N   1 
ATOM   12179 C  CA  . LYS B 1 697 ? 139.009 168.441 166.239 1.00 46.39  ? 697  LYS B CA  1 
ATOM   12180 C  C   . LYS B 1 697 ? 138.699 167.655 164.973 1.00 46.39  ? 697  LYS B C   1 
ATOM   12181 O  O   . LYS B 1 697 ? 138.332 168.238 163.945 1.00 46.39  ? 697  LYS B O   1 
ATOM   12182 C  CB  . LYS B 1 697 ? 140.516 168.632 166.405 1.00 46.39  ? 697  LYS B CB  1 
ATOM   12183 C  CG  . LYS B 1 697 ? 141.281 168.793 165.105 1.00 46.39  ? 697  LYS B CG  1 
ATOM   12184 C  CD  . LYS B 1 697 ? 142.711 168.299 165.246 1.00 46.39  ? 697  LYS B CD  1 
ATOM   12185 C  CE  . LYS B 1 697 ? 143.387 168.900 166.466 1.00 46.39  ? 697  LYS B CE  1 
ATOM   12186 N  NZ  . LYS B 1 697 ? 144.781 168.404 166.620 1.00 46.39  ? 697  LYS B NZ  1 
ATOM   12187 N  N   . TYR B 1 698 ? 138.840 166.328 165.030 1.00 44.64  ? 698  TYR B N   1 
ATOM   12188 C  CA  . TYR B 1 698 ? 138.497 165.479 163.894 1.00 44.64  ? 698  TYR B CA  1 
ATOM   12189 C  C   . TYR B 1 698 ? 137.058 165.713 163.459 1.00 44.64  ? 698  TYR B C   1 
ATOM   12190 O  O   . TYR B 1 698 ? 136.777 165.989 162.282 1.00 44.64  ? 698  TYR B O   1 
ATOM   12191 C  CB  . TYR B 1 698 ? 138.690 164.009 164.271 1.00 44.64  ? 698  TYR B CB  1 
ATOM   12192 C  CG  . TYR B 1 698 ? 138.692 163.058 163.096 1.00 44.64  ? 698  TYR B CG  1 
ATOM   12193 C  CD1 . TYR B 1 698 ? 139.864 162.744 162.437 1.00 44.64  ? 698  TYR B CD1 1 
ATOM   12194 C  CD2 . TYR B 1 698 ? 137.512 162.501 162.628 1.00 44.64  ? 698  TYR B CD2 1 
ATOM   12195 C  CE1 . TYR B 1 698 ? 139.872 161.879 161.366 1.00 44.64  ? 698  TYR B CE1 1 
ATOM   12196 C  CE2 . TYR B 1 698 ? 137.511 161.640 161.549 1.00 44.64  ? 698  TYR B CE2 1 
ATOM   12197 C  CZ  . TYR B 1 698 ? 138.693 161.332 160.922 1.00 44.64  ? 698  TYR B CZ  1 
ATOM   12198 O  OH  . TYR B 1 698 ? 138.695 160.474 159.848 1.00 44.64  ? 698  TYR B OH  1 
ATOM   12199 N  N   . ILE B 1 699 ? 136.130 165.610 164.415 1.00 44.35  ? 699  ILE B N   1 
ATOM   12200 C  CA  . ILE B 1 699 ? 134.713 165.748 164.087 1.00 44.35  ? 699  ILE B CA  1 
ATOM   12201 C  C   . ILE B 1 699 ? 134.434 167.134 163.522 1.00 44.35  ? 699  ILE B C   1 
ATOM   12202 O  O   . ILE B 1 699 ? 133.755 167.282 162.497 1.00 44.35  ? 699  ILE B O   1 
ATOM   12203 C  CB  . ILE B 1 699 ? 133.840 165.457 165.320 1.00 44.35  ? 699  ILE B CB  1 
ATOM   12204 C  CG1 . ILE B 1 699 ? 134.148 164.067 165.879 1.00 44.35  ? 699  ILE B CG1 1 
ATOM   12205 C  CG2 . ILE B 1 699 ? 132.368 165.577 164.966 1.00 44.35  ? 699  ILE B CG2 1 
ATOM   12206 C  CD1 . ILE B 1 699 ? 133.418 163.757 167.165 1.00 44.35  ? 699  ILE B CD1 1 
ATOM   12207 N  N   . LYS B 1 700 ? 134.971 168.169 164.173 1.00 48.75  ? 700  LYS B N   1 
ATOM   12208 C  CA  . LYS B 1 700 ? 134.717 169.541 163.750 1.00 48.75  ? 700  LYS B CA  1 
ATOM   12209 C  C   . LYS B 1 700 ? 135.204 169.777 162.328 1.00 48.75  ? 700  LYS B C   1 
ATOM   12210 O  O   . LYS B 1 700 ? 134.467 170.296 161.483 1.00 48.75  ? 700  LYS B O   1 
ATOM   12211 C  CB  . LYS B 1 700 ? 135.392 170.515 164.716 1.00 48.75  ? 700  LYS B CB  1 
ATOM   12212 C  CG  . LYS B 1 700 ? 134.660 170.707 166.033 1.00 48.75  ? 700  LYS B CG  1 
ATOM   12213 C  CD  . LYS B 1 700 ? 135.360 171.740 166.905 1.00 48.75  ? 700  LYS B CD  1 
ATOM   12214 C  CE  . LYS B 1 700 ? 136.874 171.598 166.833 1.00 48.75  ? 700  LYS B CE  1 
ATOM   12215 N  NZ  . LYS B 1 700 ? 137.578 172.663 167.600 1.00 48.75  ? 700  LYS B NZ  1 
ATOM   12216 N  N   . MET B 1 701 ? 136.453 169.397 162.044 1.00 49.18  ? 701  MET B N   1 
ATOM   12217 C  CA  . MET B 1 701 ? 137.021 169.662 160.727 1.00 49.18  ? 701  MET B CA  1 
ATOM   12218 C  C   . MET B 1 701 ? 136.289 168.888 159.639 1.00 49.18  ? 701  MET B C   1 
ATOM   12219 O  O   . MET B 1 701 ? 135.948 169.454 158.590 1.00 49.18  ? 701  MET B O   1 
ATOM   12220 C  CB  . MET B 1 701 ? 138.509 169.321 160.722 1.00 49.18  ? 701  MET B CB  1 
ATOM   12221 C  CG  . MET B 1 701 ? 139.335 170.180 161.660 1.00 49.18  ? 701  MET B CG  1 
ATOM   12222 S  SD  . MET B 1 701 ? 141.086 169.775 161.595 1.00 49.18  ? 701  MET B SD  1 
ATOM   12223 C  CE  . MET B 1 701 ? 141.009 167.988 161.543 1.00 49.18  ? 701  MET B CE  1 
ATOM   12224 N  N   . THR B 1 702 ? 136.034 167.595 159.865 1.00 51.74  ? 702  THR B N   1 
ATOM   12225 C  CA  . THR B 1 702 ? 135.347 166.805 158.848 1.00 51.74  ? 702  THR B CA  1 
ATOM   12226 C  C   . THR B 1 702 ? 133.958 167.365 158.570 1.00 51.74  ? 702  THR B C   1 
ATOM   12227 O  O   . THR B 1 702 ? 133.575 167.565 157.407 1.00 51.74  ? 702  THR B O   1 
ATOM   12228 C  CB  . THR B 1 702 ? 135.262 165.344 159.287 1.00 51.74  ? 702  THR B CB  1 
ATOM   12229 O  OG1 . THR B 1 702 ? 136.582 164.792 159.366 1.00 51.74  ? 702  THR B OG1 1 
ATOM   12230 C  CG2 . THR B 1 702 ? 134.440 164.539 158.293 1.00 51.74  ? 702  THR B CG2 1 
ATOM   12231 N  N   . ALA B 1 703 ? 133.195 167.649 159.631 1.00 53.50  ? 703  ALA B N   1 
ATOM   12232 C  CA  . ALA B 1 703 ? 131.846 168.166 159.449 1.00 53.50  ? 703  ALA B CA  1 
ATOM   12233 C  C   . ALA B 1 703 ? 131.860 169.518 158.750 1.00 53.50  ? 703  ALA B C   1 
ATOM   12234 O  O   . ALA B 1 703 ? 131.053 169.760 157.847 1.00 53.50  ? 703  ALA B O   1 
ATOM   12235 C  CB  . ALA B 1 703 ? 131.137 168.266 160.798 1.00 53.50  ? 703  ALA B CB  1 
ATOM   12236 N  N   . SER B 1 704 ? 132.775 170.408 159.142 1.00 55.98  ? 704  SER B N   1 
ATOM   12237 C  CA  . SER B 1 704 ? 132.818 171.736 158.540 1.00 55.98  ? 704  SER B CA  1 
ATOM   12238 C  C   . SER B 1 704 ? 133.154 171.658 157.057 1.00 55.98  ? 704  SER B C   1 
ATOM   12239 O  O   . SER B 1 704 ? 132.500 172.302 156.228 1.00 55.98  ? 704  SER B O   1 
ATOM   12240 C  CB  . SER B 1 704 ? 133.831 172.611 159.277 1.00 55.98  ? 704  SER B CB  1 
ATOM   12241 O  OG  . SER B 1 704 ? 135.150 172.352 158.829 1.00 55.98  ? 704  SER B OG  1 
ATOM   12242 N  N   . SER B 1 705 ? 134.166 170.862 156.698 1.00 56.80  ? 705  SER B N   1 
ATOM   12243 C  CA  . SER B 1 705 ? 134.554 170.769 155.293 1.00 56.80  ? 705  SER B CA  1 
ATOM   12244 C  C   . SER B 1 705 ? 133.444 170.154 154.449 1.00 56.80  ? 705  SER B C   1 
ATOM   12245 O  O   . SER B 1 705 ? 133.125 170.655 153.360 1.00 56.80  ? 705  SER B O   1 
ATOM   12246 C  CB  . SER B 1 705 ? 135.843 169.960 155.159 1.00 56.80  ? 705  SER B CB  1 
ATOM   12247 O  OG  . SER B 1 705 ? 136.970 170.739 155.518 1.00 56.80  ? 705  SER B OG  1 
ATOM   12248 N  N   . ASN B 1 706 ? 132.833 169.071 154.936 1.00 60.16  ? 706  ASN B N   1 
ATOM   12249 C  CA  . ASN B 1 706 ? 131.786 168.425 154.154 1.00 60.16  ? 706  ASN B CA  1 
ATOM   12250 C  C   . ASN B 1 706 ? 130.541 169.300 154.048 1.00 60.16  ? 706  ASN B C   1 
ATOM   12251 O  O   . ASN B 1 706 ? 129.904 169.343 152.988 1.00 60.16  ? 706  ASN B O   1 
ATOM   12252 C  CB  . ASN B 1 706 ? 131.472 167.061 154.761 1.00 60.16  ? 706  ASN B CB  1 
ATOM   12253 C  CG  . ASN B 1 706 ? 132.699 166.168 154.825 1.00 60.16  ? 706  ASN B CG  1 
ATOM   12254 O  OD1 . ASN B 1 706 ? 133.809 166.606 154.523 1.00 60.16  ? 706  ASN B OD1 1 
ATOM   12255 N  ND2 . ASN B 1 706 ? 132.512 164.922 155.237 1.00 60.16  ? 706  ASN B ND2 1 
ATOM   12256 N  N   . PHE B 1 707 ? 130.194 170.023 155.117 1.00 61.92  ? 707  PHE B N   1 
ATOM   12257 C  CA  . PHE B 1 707 ? 129.075 170.955 155.050 1.00 61.92  ? 707  PHE B CA  1 
ATOM   12258 C  C   . PHE B 1 707 ? 129.361 172.093 154.082 1.00 61.92  ? 707  PHE B C   1 
ATOM   12259 O  O   . PHE B 1 707 ? 128.459 172.554 153.376 1.00 61.92  ? 707  PHE B O   1 
ATOM   12260 C  CB  . PHE B 1 707 ? 128.771 171.506 156.441 1.00 61.92  ? 707  PHE B CB  1 
ATOM   12261 C  CG  . PHE B 1 707 ? 127.898 172.723 156.428 1.00 61.92  ? 707  PHE B CG  1 
ATOM   12262 C  CD1 . PHE B 1 707 ? 126.575 172.638 156.040 1.00 61.92  ? 707  PHE B CD1 1 
ATOM   12263 C  CD2 . PHE B 1 707 ? 128.406 173.958 156.791 1.00 61.92  ? 707  PHE B CD2 1 
ATOM   12264 C  CE1 . PHE B 1 707 ? 125.773 173.757 156.027 1.00 61.92  ? 707  PHE B CE1 1 
ATOM   12265 C  CE2 . PHE B 1 707 ? 127.606 175.082 156.778 1.00 61.92  ? 707  PHE B CE2 1 
ATOM   12266 C  CZ  . PHE B 1 707 ? 126.288 174.982 156.395 1.00 61.92  ? 707  PHE B CZ  1 
ATOM   12267 N  N   . GLY B 1 708 ? 130.605 172.573 154.046 1.00 65.29  ? 708  GLY B N   1 
ATOM   12268 C  CA  . GLY B 1 708 ? 130.959 173.592 153.072 1.00 65.29  ? 708  GLY B CA  1 
ATOM   12269 C  C   . GLY B 1 708 ? 130.816 173.100 151.646 1.00 65.29  ? 708  GLY B C   1 
ATOM   12270 O  O   . GLY B 1 708 ? 130.311 173.818 150.777 1.00 65.29  ? 708  GLY B O   1 
ATOM   12271 N  N   . ASN B 1 709 ? 131.254 171.866 151.386 1.00 63.70  ? 709  ASN B N   1 
ATOM   12272 C  CA  . ASN B 1 709 ? 131.071 171.291 150.055 1.00 63.70  ? 709  ASN B CA  1 
ATOM   12273 C  C   . ASN B 1 709 ? 129.591 171.176 149.702 1.00 63.70  ? 709  ASN B C   1 
ATOM   12274 O  O   . ASN B 1 709 ? 129.184 171.498 148.577 1.00 63.70  ? 709  ASN B O   1 
ATOM   12275 C  CB  . ASN B 1 709 ? 131.752 169.926 149.970 1.00 63.70  ? 709  ASN B CB  1 
ATOM   12276 C  CG  . ASN B 1 709 ? 133.264 170.025 150.018 1.00 63.70  ? 709  ASN B CG  1 
ATOM   12277 O  OD1 . ASN B 1 709 ? 133.830 171.113 149.915 1.00 63.70  ? 709  ASN B OD1 1 
ATOM   12278 N  ND2 . ASN B 1 709 ? 133.926 168.886 150.174 1.00 63.70  ? 709  ASN B ND2 1 
ATOM   12279 N  N   . VAL B 1 710 ? 128.770 170.725 150.655 1.00 67.41  ? 710  VAL B N   1 
ATOM   12280 C  CA  . VAL B 1 710 ? 127.335 170.599 150.405 1.00 67.41  ? 710  VAL B CA  1 
ATOM   12281 C  C   . VAL B 1 710 ? 126.718 171.962 150.116 1.00 67.41  ? 710  VAL B C   1 
ATOM   12282 O  O   . VAL B 1 710 ? 125.885 172.104 149.213 1.00 67.41  ? 710  VAL B O   1 
ATOM   12283 C  CB  . VAL B 1 710 ? 126.641 169.905 151.591 1.00 67.41  ? 710  VAL B CB  1 
ATOM   12284 C  CG1 . VAL B 1 710 ? 125.131 169.949 151.426 1.00 67.41  ? 710  VAL B CG1 1 
ATOM   12285 C  CG2 . VAL B 1 710 ? 127.113 168.470 151.711 1.00 67.41  ? 710  VAL B CG2 1 
ATOM   12286 N  N   . PHE B 1 711 ? 127.104 172.983 150.885 1.00 69.76  ? 711  PHE B N   1 
ATOM   12287 C  CA  . PHE B 1 711 ? 126.568 174.323 150.666 1.00 69.76  ? 711  PHE B CA  1 
ATOM   12288 C  C   . PHE B 1 711 ? 126.968 174.861 149.299 1.00 69.76  ? 711  PHE B C   1 
ATOM   12289 O  O   . PHE B 1 711 ? 126.152 175.480 148.606 1.00 69.76  ? 711  PHE B O   1 
ATOM   12290 C  CB  . PHE B 1 711 ? 127.042 175.265 151.772 1.00 69.76  ? 711  PHE B CB  1 
ATOM   12291 C  CG  . PHE B 1 711 ? 126.348 176.596 151.771 1.00 69.76  ? 711  PHE B CG  1 
ATOM   12292 C  CD1 . PHE B 1 711 ? 124.966 176.671 151.766 1.00 69.76  ? 711  PHE B CD1 1 
ATOM   12293 C  CD2 . PHE B 1 711 ? 127.077 177.772 151.778 1.00 69.76  ? 711  PHE B CD2 1 
ATOM   12294 C  CE1 . PHE B 1 711 ? 124.324 177.894 151.767 1.00 69.76  ? 711  PHE B CE1 1 
ATOM   12295 C  CE2 . PHE B 1 711 ? 126.442 178.998 151.778 1.00 69.76  ? 711  PHE B CE2 1 
ATOM   12296 C  CZ  . PHE B 1 711 ? 125.063 179.059 151.772 1.00 69.76  ? 711  PHE B CZ  1 
ATOM   12297 N  N   . SER B 1 712 ? 128.225 174.644 148.901 1.00 71.73  ? 712  SER B N   1 
ATOM   12298 C  CA  . SER B 1 712 ? 128.667 175.072 147.578 1.00 71.73  ? 712  SER B CA  1 
ATOM   12299 C  C   . SER B 1 712 ? 127.850 174.398 146.487 1.00 71.73  ? 712  SER B C   1 
ATOM   12300 O  O   . SER B 1 712 ? 127.390 175.055 145.542 1.00 71.73  ? 712  SER B O   1 
ATOM   12301 C  CB  . SER B 1 712 ? 130.150 174.756 147.392 1.00 71.73  ? 712  SER B CB  1 
ATOM   12302 O  OG  . SER B 1 712 ? 130.902 175.141 148.526 1.00 71.73  ? 712  SER B OG  1 
ATOM   12303 N  N   . VAL B 1 713 ? 127.651 173.084 146.611 1.00 71.81  ? 713  VAL B N   1 
ATOM   12304 C  CA  . VAL B 1 713 ? 126.845 172.354 145.638 1.00 71.81  ? 713  VAL B CA  1 
ATOM   12305 C  C   . VAL B 1 713 ? 125.431 172.916 145.585 1.00 71.81  ? 713  VAL B C   1 
ATOM   12306 O  O   . VAL B 1 713 ? 124.870 173.124 144.503 1.00 71.81  ? 713  VAL B O   1 
ATOM   12307 C  CB  . VAL B 1 713 ? 126.844 170.853 145.972 1.00 71.81  ? 713  VAL B CB  1 
ATOM   12308 C  CG1 . VAL B 1 713 ? 125.770 170.145 145.185 1.00 71.81  ? 713  VAL B CG1 1 
ATOM   12309 C  CG2 . VAL B 1 713 ? 128.206 170.248 145.674 1.00 71.81  ? 713  VAL B CG2 1 
ATOM   12310 N  N   . LEU B 1 714 ? 124.836 173.173 146.750 1.00 74.15  ? 714  LEU B N   1 
ATOM   12311 C  CA  . LEU B 1 714 ? 123.461 173.657 146.790 1.00 74.15  ? 714  LEU B CA  1 
ATOM   12312 C  C   . LEU B 1 714 ? 123.331 175.026 146.133 1.00 74.15  ? 714  LEU B C   1 
ATOM   12313 O  O   . LEU B 1 714 ? 122.388 175.268 145.370 1.00 74.15  ? 714  LEU B O   1 
ATOM   12314 C  CB  . LEU B 1 714 ? 122.968 173.705 148.236 1.00 74.15  ? 714  LEU B CB  1 
ATOM   12315 C  CG  . LEU B 1 714 ? 121.483 173.987 148.471 1.00 74.15  ? 714  LEU B CG  1 
ATOM   12316 C  CD1 . LEU B 1 714 ? 120.957 173.117 149.600 1.00 74.15  ? 714  LEU B CD1 1 
ATOM   12317 C  CD2 . LEU B 1 714 ? 121.249 175.457 148.781 1.00 74.15  ? 714  LEU B CD2 1 
ATOM   12318 N  N   . VAL B 1 715 ? 124.263 175.938 146.417 1.00 75.83  ? 715  VAL B N   1 
ATOM   12319 C  CA  . VAL B 1 715 ? 124.114 177.302 145.917 1.00 75.83  ? 715  VAL B CA  1 
ATOM   12320 C  C   . VAL B 1 715 ? 124.446 177.381 144.430 1.00 75.83  ? 715  VAL B C   1 
ATOM   12321 O  O   . VAL B 1 715 ? 123.788 178.109 143.677 1.00 75.83  ? 715  VAL B O   1 
ATOM   12322 C  CB  . VAL B 1 715 ? 124.965 178.288 146.742 1.00 75.83  ? 715  VAL B CB  1 
ATOM   12323 C  CG1 . VAL B 1 715 ? 124.454 178.361 148.176 1.00 75.83  ? 715  VAL B CG1 1 
ATOM   12324 C  CG2 . VAL B 1 715 ? 126.441 177.921 146.699 1.00 75.83  ? 715  VAL B CG2 1 
ATOM   12325 N  N   . ALA B 1 716 ? 125.460 176.641 143.977 1.00 78.75  ? 716  ALA B N   1 
ATOM   12326 C  CA  . ALA B 1 716 ? 126.011 176.844 142.643 1.00 78.75  ? 716  ALA B CA  1 
ATOM   12327 C  C   . ALA B 1 716 ? 125.478 175.866 141.601 1.00 78.75  ? 716  ALA B C   1 
ATOM   12328 O  O   . ALA B 1 716 ? 125.900 175.929 140.441 1.00 78.75  ? 716  ALA B O   1 
ATOM   12329 C  CB  . ALA B 1 716 ? 127.537 176.768 142.692 1.00 78.75  ? 716  ALA B CB  1 
ATOM   12330 N  N   . SER B 1 717 ? 124.567 174.966 141.972 1.00 80.63  ? 717  SER B N   1 
ATOM   12331 C  CA  . SER B 1 717 ? 124.082 173.984 141.008 1.00 80.63  ? 717  SER B CA  1 
ATOM   12332 C  C   . SER B 1 717 ? 123.081 174.576 140.023 1.00 80.63  ? 717  SER B C   1 
ATOM   12333 O  O   . SER B 1 717 ? 123.023 174.136 138.870 1.00 80.63  ? 717  SER B O   1 
ATOM   12334 C  CB  . SER B 1 717 ? 123.447 172.796 141.732 1.00 80.63  ? 717  SER B CB  1 
ATOM   12335 O  OG  . SER B 1 717 ? 122.119 173.092 142.127 1.00 80.63  ? 717  SER B OG  1 
ATOM   12336 N  N   . ALA B 1 718 ? 122.289 175.561 140.454 1.00 84.30  ? 718  ALA B N   1 
ATOM   12337 C  CA  . ALA B 1 718 ? 121.203 176.063 139.616 1.00 84.30  ? 718  ALA B CA  1 
ATOM   12338 C  C   . ALA B 1 718 ? 121.726 176.739 138.354 1.00 84.30  ? 718  ALA B C   1 
ATOM   12339 O  O   . ALA B 1 718 ? 121.193 176.518 137.261 1.00 84.30  ? 718  ALA B O   1 
ATOM   12340 C  CB  . ALA B 1 718 ? 120.329 177.027 140.416 1.00 84.30  ? 718  ALA B CB  1 
ATOM   12341 N  N   . PHE B 1 719 ? 122.765 177.566 138.483 1.00 84.68  ? 719  PHE B N   1 
ATOM   12342 C  CA  . PHE B 1 719 ? 123.237 178.335 137.335 1.00 84.68  ? 719  PHE B CA  1 
ATOM   12343 C  C   . PHE B 1 719 ? 123.922 177.444 136.305 1.00 84.68  ? 719  PHE B C   1 
ATOM   12344 O  O   . PHE B 1 719 ? 123.773 177.658 135.096 1.00 84.68  ? 719  PHE B O   1 
ATOM   12345 C  CB  . PHE B 1 719 ? 124.179 179.445 137.798 1.00 84.68  ? 719  PHE B CB  1 
ATOM   12346 C  CG  . PHE B 1 719 ? 123.618 180.294 138.903 1.00 84.68  ? 719  PHE B CG  1 
ATOM   12347 C  CD1 . PHE B 1 719 ? 122.322 180.778 138.832 1.00 84.68  ? 719  PHE B CD1 1 
ATOM   12348 C  CD2 . PHE B 1 719 ? 124.388 180.612 140.009 1.00 84.68  ? 719  PHE B CD2 1 
ATOM   12349 C  CE1 . PHE B 1 719 ? 121.804 181.561 139.845 1.00 84.68  ? 719  PHE B CE1 1 
ATOM   12350 C  CE2 . PHE B 1 719 ? 123.875 181.395 141.025 1.00 84.68  ? 719  PHE B CE2 1 
ATOM   12351 C  CZ  . PHE B 1 719 ? 122.581 181.870 140.943 1.00 84.68  ? 719  PHE B CZ  1 
ATOM   12352 N  N   . LEU B 1 720 ? 124.677 176.448 136.759 1.00 85.82  ? 720  LEU B N   1 
ATOM   12353 C  CA  . LEU B 1 720 ? 125.411 175.597 135.839 1.00 85.82  ? 720  LEU B CA  1 
ATOM   12354 C  C   . LEU B 1 720 ? 124.453 174.706 135.049 1.00 85.82  ? 720  LEU B C   1 
ATOM   12355 O  O   . LEU B 1 720 ? 123.422 174.271 135.568 1.00 85.82  ? 720  LEU B O   1 
ATOM   12356 C  CB  . LEU B 1 720 ? 126.415 174.734 136.597 1.00 85.82  ? 720  LEU B CB  1 
ATOM   12357 C  CG  . LEU B 1 720 ? 127.533 175.484 137.322 1.00 85.82  ? 720  LEU B CG  1 
ATOM   12358 C  CD1 . LEU B 1 720 ? 128.385 174.524 138.136 1.00 85.82  ? 720  LEU B CD1 1 
ATOM   12359 C  CD2 . LEU B 1 720 ? 128.389 176.260 136.334 1.00 85.82  ? 720  LEU B CD2 1 
ATOM   12360 N  N   . PRO B 1 721 ? 124.772 174.420 133.788 1.00 87.63  ? 721  PRO B N   1 
ATOM   12361 C  CA  . PRO B 1 721 ? 123.955 173.496 132.988 1.00 87.63  ? 721  PRO B CA  1 
ATOM   12362 C  C   . PRO B 1 721 ? 124.330 172.029 133.134 1.00 87.63  ? 721  PRO B C   1 
ATOM   12363 O  O   . PRO B 1 721 ? 123.796 171.201 132.390 1.00 87.63  ? 721  PRO B O   1 
ATOM   12364 C  CB  . PRO B 1 721 ? 124.227 173.976 131.556 1.00 87.63  ? 721  PRO B CB  1 
ATOM   12365 C  CG  . PRO B 1 721 ? 125.602 174.575 131.602 1.00 87.63  ? 721  PRO B CG  1 
ATOM   12366 C  CD  . PRO B 1 721 ? 125.925 174.936 133.031 1.00 87.63  ? 721  PRO B CD  1 
ATOM   12367 N  N   . PHE B 1 722 ? 125.225 171.694 134.058 1.00 89.59  ? 722  PHE B N   1 
ATOM   12368 C  CA  . PHE B 1 722 ? 125.614 170.313 134.305 1.00 89.59  ? 722  PHE B CA  1 
ATOM   12369 C  C   . PHE B 1 722 ? 126.050 170.200 135.758 1.00 89.59  ? 722  PHE B C   1 
ATOM   12370 O  O   . PHE B 1 722 ? 126.138 171.197 136.479 1.00 89.59  ? 722  PHE B O   1 
ATOM   12371 C  CB  . PHE B 1 722 ? 126.723 169.856 133.351 1.00 89.59  ? 722  PHE B CB  1 
ATOM   12372 C  CG  . PHE B 1 722 ? 127.859 170.830 133.227 1.00 89.59  ? 722  PHE B CG  1 
ATOM   12373 C  CD1 . PHE B 1 722 ? 127.820 171.847 132.289 1.00 89.59  ? 722  PHE B CD1 1 
ATOM   12374 C  CD2 . PHE B 1 722 ? 128.967 170.726 134.049 1.00 89.59  ? 722  PHE B CD2 1 
ATOM   12375 C  CE1 . PHE B 1 722 ? 128.864 172.743 132.174 1.00 89.59  ? 722  PHE B CE1 1 
ATOM   12376 C  CE2 . PHE B 1 722 ? 130.013 171.618 133.937 1.00 89.59  ? 722  PHE B CE2 1 
ATOM   12377 C  CZ  . PHE B 1 722 ? 129.962 172.628 133.000 1.00 89.59  ? 722  PHE B CZ  1 
ATOM   12378 N  N   . LEU B 1 723 ? 126.309 168.971 136.180 1.00 85.62  ? 723  LEU B N   1 
ATOM   12379 C  CA  . LEU B 1 723 ? 126.742 168.737 137.551 1.00 85.62  ? 723  LEU B CA  1 
ATOM   12380 C  C   . LEU B 1 723 ? 128.100 169.391 137.782 1.00 85.62  ? 723  LEU B C   1 
ATOM   12381 O  O   . LEU B 1 723 ? 129.011 169.219 136.963 1.00 85.62  ? 723  LEU B O   1 
ATOM   12382 C  CB  . LEU B 1 723 ? 126.820 167.240 137.838 1.00 85.62  ? 723  LEU B CB  1 
ATOM   12383 C  CG  . LEU B 1 723 ? 125.565 166.428 137.513 1.00 85.62  ? 723  LEU B CG  1 
ATOM   12384 C  CD1 . LEU B 1 723 ? 125.789 164.957 137.823 1.00 85.62  ? 723  LEU B CD1 1 
ATOM   12385 C  CD2 . LEU B 1 723 ? 124.362 166.964 138.273 1.00 85.62  ? 723  LEU B CD2 1 
ATOM   12386 N  N   . PRO B 1 724 ? 128.272 170.154 138.864 1.00 80.33  ? 724  PRO B N   1 
ATOM   12387 C  CA  . PRO B 1 724 ? 129.582 170.776 139.120 1.00 80.33  ? 724  PRO B CA  1 
ATOM   12388 C  C   . PRO B 1 724 ? 130.705 169.765 139.242 1.00 80.33  ? 724  PRO B C   1 
ATOM   12389 O  O   . PRO B 1 724 ? 131.841 170.058 138.850 1.00 80.33  ? 724  PRO B O   1 
ATOM   12390 C  CB  . PRO B 1 724 ? 129.358 171.535 140.435 1.00 80.33  ? 724  PRO B CB  1 
ATOM   12391 C  CG  . PRO B 1 724 ? 127.878 171.746 140.506 1.00 80.33  ? 724  PRO B CG  1 
ATOM   12392 C  CD  . PRO B 1 724 ? 127.271 170.532 139.875 1.00 80.33  ? 724  PRO B CD  1 
ATOM   12393 N  N   . MET B 1 725 ? 130.418 168.582 139.778 1.00 79.13  ? 725  MET B N   1 
ATOM   12394 C  CA  . MET B 1 725 ? 131.380 167.494 139.836 1.00 79.13  ? 725  MET B CA  1 
ATOM   12395 C  C   . MET B 1 725 ? 130.615 166.184 139.743 1.00 79.13  ? 725  MET B C   1 
ATOM   12396 O  O   . MET B 1 725 ? 129.512 166.067 140.281 1.00 79.13  ? 725  MET B O   1 
ATOM   12397 C  CB  . MET B 1 725 ? 132.207 167.536 141.125 1.00 79.13  ? 725  MET B CB  1 
ATOM   12398 C  CG  . MET B 1 725 ? 133.531 166.799 141.038 1.00 79.13  ? 725  MET B CG  1 
ATOM   12399 S  SD  . MET B 1 725 ? 134.234 166.435 142.658 1.00 79.13  ? 725  MET B SD  1 
ATOM   12400 C  CE  . MET B 1 725 ? 134.647 168.078 143.234 1.00 79.13  ? 725  MET B CE  1 
ATOM   12401 N  N   . LEU B 1 726 ? 131.196 165.210 139.052 1.00 74.58  ? 726  LEU B N   1 
ATOM   12402 C  CA  . LEU B 1 726 ? 130.566 163.902 138.981 1.00 74.58  ? 726  LEU B CA  1 
ATOM   12403 C  C   . LEU B 1 726 ? 130.544 163.265 140.368 1.00 74.58  ? 726  LEU B C   1 
ATOM   12404 O  O   . LEU B 1 726 ? 131.522 163.368 141.115 1.00 74.58  ? 726  LEU B O   1 
ATOM   12405 C  CB  . LEU B 1 726 ? 131.299 162.994 137.995 1.00 74.58  ? 726  LEU B CB  1 
ATOM   12406 C  CG  . LEU B 1 726 ? 130.767 163.007 136.561 1.00 74.58  ? 726  LEU B CG  1 
ATOM   12407 C  CD1 . LEU B 1 726 ? 131.732 162.307 135.617 1.00 74.58  ? 726  LEU B CD1 1 
ATOM   12408 C  CD2 . LEU B 1 726 ? 129.388 162.370 136.493 1.00 74.58  ? 726  LEU B CD2 1 
ATOM   12409 N  N   . PRO B 1 727 ? 129.442 162.614 140.745 1.00 71.10  ? 727  PRO B N   1 
ATOM   12410 C  CA  . PRO B 1 727 ? 129.371 162.012 142.085 1.00 71.10  ? 727  PRO B CA  1 
ATOM   12411 C  C   . PRO B 1 727 ? 130.447 160.974 142.333 1.00 71.10  ? 727  PRO B C   1 
ATOM   12412 O  O   . PRO B 1 727 ? 130.850 160.775 143.485 1.00 71.10  ? 727  PRO B O   1 
ATOM   12413 C  CB  . PRO B 1 727 ? 127.969 161.393 142.114 1.00 71.10  ? 727  PRO B CB  1 
ATOM   12414 C  CG  . PRO B 1 727 ? 127.201 162.134 141.066 1.00 71.10  ? 727  PRO B CG  1 
ATOM   12415 C  CD  . PRO B 1 727 ? 128.192 162.434 139.990 1.00 71.10  ? 727  PRO B CD  1 
ATOM   12416 N  N   . LEU B 1 728 ? 130.918 160.297 141.285 1.00 73.27  ? 728  LEU B N   1 
ATOM   12417 C  CA  . LEU B 1 728 ? 132.043 159.383 141.442 1.00 73.27  ? 728  LEU B CA  1 
ATOM   12418 C  C   . LEU B 1 728 ? 133.287 160.134 141.900 1.00 73.27  ? 728  LEU B C   1 
ATOM   12419 O  O   . LEU B 1 728 ? 134.026 159.662 142.774 1.00 73.27  ? 728  LEU B O   1 
ATOM   12420 C  CB  . LEU B 1 728 ? 132.293 158.651 140.123 1.00 73.27  ? 728  LEU B CB  1 
ATOM   12421 C  CG  . LEU B 1 728 ? 133.283 157.490 140.039 1.00 73.27  ? 728  LEU B CG  1 
ATOM   12422 C  CD1 . LEU B 1 728 ? 132.858 156.572 138.908 1.00 73.27  ? 728  LEU B CD1 1 
ATOM   12423 C  CD2 . LEU B 1 728 ? 134.705 157.975 139.814 1.00 73.27  ? 728  LEU B CD2 1 
ATOM   12424 N  N   . HIS B 1 729 ? 133.527 161.316 141.328 1.00 76.70  ? 729  HIS B N   1 
ATOM   12425 C  CA  . HIS B 1 729 ? 134.643 162.139 141.778 1.00 76.70  ? 729  HIS B CA  1 
ATOM   12426 C  C   . HIS B 1 729 ? 134.450 162.588 143.221 1.00 76.70  ? 729  HIS B C   1 
ATOM   12427 O  O   . HIS B 1 729 ? 135.419 162.684 143.980 1.00 76.70  ? 729  HIS B O   1 
ATOM   12428 C  CB  . HIS B 1 729 ? 134.817 163.345 140.856 1.00 76.70  ? 729  HIS B CB  1 
ATOM   12429 C  CG  . HIS B 1 729 ? 134.954 162.984 139.410 1.00 76.70  ? 729  HIS B CG  1 
ATOM   12430 N  ND1 . HIS B 1 729 ? 134.465 163.778 138.395 1.00 76.70  ? 729  HIS B ND1 1 
ATOM   12431 C  CD2 . HIS B 1 729 ? 135.526 161.915 138.807 1.00 76.70  ? 729  HIS B CD2 1 
ATOM   12432 C  CE1 . HIS B 1 729 ? 134.730 163.214 137.230 1.00 76.70  ? 729  HIS B CE1 1 
ATOM   12433 N  NE2 . HIS B 1 729 ? 135.372 162.082 137.452 1.00 76.70  ? 729  HIS B NE2 1 
ATOM   12434 N  N   . LEU B 1 730 ? 133.207 162.872 143.618 1.00 72.15  ? 730  LEU B N   1 
ATOM   12435 C  CA  . LEU B 1 730 ? 132.944 163.240 145.006 1.00 72.15  ? 730  LEU B CA  1 
ATOM   12436 C  C   . LEU B 1 730 ? 133.232 162.082 145.953 1.00 72.15  ? 730  LEU B C   1 
ATOM   12437 O  O   . LEU B 1 730 ? 133.777 162.286 147.043 1.00 72.15  ? 730  LEU B O   1 
ATOM   12438 C  CB  . LEU B 1 730 ? 131.500 163.709 145.161 1.00 72.15  ? 730  LEU B CB  1 
ATOM   12439 C  CG  . LEU B 1 730 ? 131.208 165.096 144.596 1.00 72.15  ? 730  LEU B CG  1 
ATOM   12440 C  CD1 . LEU B 1 730 ? 129.794 165.139 144.075 1.00 72.15  ? 730  LEU B CD1 1 
ATOM   12441 C  CD2 . LEU B 1 730 ? 131.424 166.163 145.653 1.00 72.15  ? 730  LEU B CD2 1 
ATOM   12442 N  N   . LEU B 1 731 ? 132.857 160.862 145.563 1.00 69.91  ? 731  LEU B N   1 
ATOM   12443 C  CA  . LEU B 1 731 ? 133.178 159.697 146.381 1.00 69.91  ? 731  LEU B CA  1 
ATOM   12444 C  C   . LEU B 1 731 ? 134.684 159.496 146.479 1.00 69.91  ? 731  LEU B C   1 
ATOM   12445 O  O   . LEU B 1 731 ? 135.206 159.162 147.550 1.00 69.91  ? 731  LEU B O   1 
ATOM   12446 C  CB  . LEU B 1 731 ? 132.503 158.449 145.810 1.00 69.91  ? 731  LEU B CB  1 
ATOM   12447 C  CG  . LEU B 1 731 ? 130.974 158.448 145.780 1.00 69.91  ? 731  LEU B CG  1 
ATOM   12448 C  CD1 . LEU B 1 731 ? 130.448 157.041 145.554 1.00 69.91  ? 731  LEU B CD1 1 
ATOM   12449 C  CD2 . LEU B 1 731 ? 130.409 159.033 147.064 1.00 69.91  ? 731  LEU B CD2 1 
ATOM   12450 N  N   . ILE B 1 732 ? 135.398 159.696 145.369 1.00 71.33  ? 732  ILE B N   1 
ATOM   12451 C  CA  . ILE B 1 732 ? 136.857 159.610 145.398 1.00 71.33  ? 732  ILE B CA  1 
ATOM   12452 C  C   . ILE B 1 732 ? 137.428 160.647 146.356 1.00 71.33  ? 732  ILE B C   1 
ATOM   12453 O  O   . ILE B 1 732 ? 138.326 160.353 147.157 1.00 71.33  ? 732  ILE B O   1 
ATOM   12454 C  CB  . ILE B 1 732 ? 137.428 159.779 143.978 1.00 71.33  ? 732  ILE B CB  1 
ATOM   12455 C  CG1 . ILE B 1 732 ? 137.157 158.530 143.139 1.00 71.33  ? 732  ILE B CG1 1 
ATOM   12456 C  CG2 . ILE B 1 732 ? 138.918 160.072 144.030 1.00 71.33  ? 732  ILE B CG2 1 
ATOM   12457 C  CD1 . ILE B 1 732 ? 137.756 158.591 141.754 1.00 71.33  ? 732  ILE B CD1 1 
ATOM   12458 N  N   . GLN B 1 733 ? 136.913 161.877 146.287 1.00 68.02  ? 733  GLN B N   1 
ATOM   12459 C  CA  . GLN B 1 733 ? 137.366 162.940 147.176 1.00 68.02  ? 733  GLN B CA  1 
ATOM   12460 C  C   . GLN B 1 733 ? 137.125 162.582 148.635 1.00 68.02  ? 733  GLN B C   1 
ATOM   12461 O  O   . GLN B 1 733 ? 138.008 162.767 149.479 1.00 68.02  ? 733  GLN B O   1 
ATOM   12462 C  CB  . GLN B 1 733 ? 136.654 164.244 146.822 1.00 68.02  ? 733  GLN B CB  1 
ATOM   12463 C  CG  . GLN B 1 733 ? 136.954 165.401 147.755 1.00 68.02  ? 733  GLN B CG  1 
ATOM   12464 C  CD  . GLN B 1 733 ? 136.235 166.672 147.350 1.00 68.02  ? 733  GLN B CD  1 
ATOM   12465 O  OE1 . GLN B 1 733 ? 135.573 166.721 146.314 1.00 68.02  ? 733  GLN B OE1 1 
ATOM   12466 N  NE2 . GLN B 1 733 ? 136.346 167.704 148.177 1.00 68.02  ? 733  GLN B NE2 1 
ATOM   12467 N  N   . ASN B 1 734 ? 135.936 162.066 148.949 1.00 66.80  ? 734  ASN B N   1 
ATOM   12468 C  CA  . ASN B 1 734 ? 135.620 161.703 150.327 1.00 66.80  ? 734  ASN B CA  1 
ATOM   12469 C  C   . ASN B 1 734 ? 136.529 160.585 150.823 1.00 66.80  ? 734  ASN B C   1 
ATOM   12470 O  O   . ASN B 1 734 ? 137.041 160.641 151.948 1.00 66.80  ? 734  ASN B O   1 
ATOM   12471 C  CB  . ASN B 1 734 ? 134.151 161.295 150.439 1.00 66.80  ? 734  ASN B CB  1 
ATOM   12472 C  CG  . ASN B 1 734 ? 133.206 162.455 150.199 1.00 66.80  ? 734  ASN B CG  1 
ATOM   12473 O  OD1 . ASN B 1 734 ? 133.635 163.574 149.918 1.00 66.80  ? 734  ASN B OD1 1 
ATOM   12474 N  ND2 . ASN B 1 734 ? 131.909 162.193 150.309 1.00 66.80  ? 734  ASN B ND2 1 
ATOM   12475 N  N   . LEU B 1 735 ? 136.750 159.564 149.992 1.00 64.23  ? 735  LEU B N   1 
ATOM   12476 C  CA  . LEU B 1 735 ? 137.607 158.454 150.392 1.00 64.23  ? 735  LEU B CA  1 
ATOM   12477 C  C   . LEU B 1 735 ? 139.036 158.922 150.646 1.00 64.23  ? 735  LEU B C   1 
ATOM   12478 O  O   . LEU B 1 735 ? 139.647 158.575 151.665 1.00 64.23  ? 735  LEU B O   1 
ATOM   12479 C  CB  . LEU B 1 735 ? 137.582 157.364 149.320 1.00 64.23  ? 735  LEU B CB  1 
ATOM   12480 C  CG  . LEU B 1 735 ? 138.668 156.294 149.425 1.00 64.23  ? 735  LEU B CG  1 
ATOM   12481 C  CD1 . LEU B 1 735 ? 138.450 155.424 150.653 1.00 64.23  ? 735  LEU B CD1 1 
ATOM   12482 C  CD2 . LEU B 1 735 ? 138.719 155.449 148.163 1.00 64.23  ? 735  LEU B CD2 1 
ATOM   12483 N  N   . LEU B 1 736 ? 139.583 159.722 149.728 1.00 67.68  ? 736  LEU B N   1 
ATOM   12484 C  CA  . LEU B 1 736 ? 140.956 160.193 149.885 1.00 67.68  ? 736  LEU B CA  1 
ATOM   12485 C  C   . LEU B 1 736 ? 141.086 161.129 151.081 1.00 67.68  ? 736  LEU B C   1 
ATOM   12486 O  O   . LEU B 1 736 ? 142.084 161.086 151.810 1.00 67.68  ? 736  LEU B O   1 
ATOM   12487 C  CB  . LEU B 1 736 ? 141.427 160.873 148.599 1.00 67.68  ? 736  LEU B CB  1 
ATOM   12488 C  CG  . LEU B 1 736 ? 141.514 159.936 147.391 1.00 67.68  ? 736  LEU B CG  1 
ATOM   12489 C  CD1 . LEU B 1 736 ? 142.184 160.615 146.212 1.00 67.68  ? 736  LEU B CD1 1 
ATOM   12490 C  CD2 . LEU B 1 736 ? 142.251 158.658 147.761 1.00 67.68  ? 736  LEU B CD2 1 
ATOM   12491 N  N   . TYR B 1 737 ? 140.084 161.983 151.305 1.00 61.63  ? 737  TYR B N   1 
ATOM   12492 C  CA  . TYR B 1 737 ? 140.117 162.865 152.464 1.00 61.63  ? 737  TYR B CA  1 
ATOM   12493 C  C   . TYR B 1 737 ? 140.068 162.071 153.762 1.00 61.63  ? 737  TYR B C   1 
ATOM   12494 O  O   . TYR B 1 737 ? 140.763 162.404 154.725 1.00 61.63  ? 737  TYR B O   1 
ATOM   12495 C  CB  . TYR B 1 737 ? 138.962 163.864 152.402 1.00 61.63  ? 737  TYR B CB  1 
ATOM   12496 C  CG  . TYR B 1 737 ? 138.872 164.742 153.626 1.00 61.63  ? 737  TYR B CG  1 
ATOM   12497 C  CD1 . TYR B 1 737 ? 139.895 165.623 153.947 1.00 61.63  ? 737  TYR B CD1 1 
ATOM   12498 C  CD2 . TYR B 1 737 ? 137.770 164.684 154.466 1.00 61.63  ? 737  TYR B CD2 1 
ATOM   12499 C  CE1 . TYR B 1 737 ? 139.821 166.426 155.067 1.00 61.63  ? 737  TYR B CE1 1 
ATOM   12500 C  CE2 . TYR B 1 737 ? 137.687 165.483 155.589 1.00 61.63  ? 737  TYR B CE2 1 
ATOM   12501 C  CZ  . TYR B 1 737 ? 138.715 166.352 155.884 1.00 61.63  ? 737  TYR B CZ  1 
ATOM   12502 O  OH  . TYR B 1 737 ? 138.637 167.150 157.002 1.00 61.63  ? 737  TYR B OH  1 
ATOM   12503 N  N   . ASP B 1 738 ? 139.250 161.017 153.809 1.00 62.55  ? 738  ASP B N   1 
ATOM   12504 C  CA  . ASP B 1 738 ? 139.206 160.173 155.000 1.00 62.55  ? 738  ASP B CA  1 
ATOM   12505 C  C   . ASP B 1 738 ? 140.543 159.475 155.223 1.00 62.55  ? 738  ASP B C   1 
ATOM   12506 O  O   . ASP B 1 738 ? 141.023 159.369 156.360 1.00 62.55  ? 738  ASP B O   1 
ATOM   12507 C  CB  . ASP B 1 738 ? 138.075 159.153 154.876 1.00 62.55  ? 738  ASP B CB  1 
ATOM   12508 C  CG  . ASP B 1 738 ? 136.706 159.780 155.050 1.00 62.55  ? 738  ASP B CG  1 
ATOM   12509 O  OD1 . ASP B 1 738 ? 136.638 160.997 155.323 1.00 62.55  ? 738  ASP B OD1 1 
ATOM   12510 O  OD2 . ASP B 1 738 ? 135.698 159.057 154.912 1.00 62.55  ? 738  ASP B OD2 1 
ATOM   12511 N  N   . VAL B 1 739 ? 141.162 158.993 154.142 1.00 61.72  ? 739  VAL B N   1 
ATOM   12512 C  CA  . VAL B 1 739 ? 142.480 158.374 154.258 1.00 61.72  ? 739  VAL B CA  1 
ATOM   12513 C  C   . VAL B 1 739 ? 143.494 159.373 154.800 1.00 61.72  ? 739  VAL B C   1 
ATOM   12514 O  O   . VAL B 1 739 ? 144.349 159.021 155.622 1.00 61.72  ? 739  VAL B O   1 
ATOM   12515 C  CB  . VAL B 1 739 ? 142.919 157.795 152.899 1.00 61.72  ? 739  VAL B CB  1 
ATOM   12516 C  CG1 . VAL B 1 739 ? 144.382 157.381 152.939 1.00 61.72  ? 739  VAL B CG1 1 
ATOM   12517 C  CG2 . VAL B 1 739 ? 142.043 156.611 152.524 1.00 61.72  ? 739  VAL B CG2 1 
ATOM   12518 N  N   . SER B 1 740 ? 143.420 160.628 154.354 1.00 60.99  ? 740  SER B N   1 
ATOM   12519 C  CA  . SER B 1 740 ? 144.292 161.664 154.899 1.00 60.99  ? 740  SER B CA  1 
ATOM   12520 C  C   . SER B 1 740 ? 144.015 161.895 156.380 1.00 60.99  ? 740  SER B C   1 
ATOM   12521 O  O   . SER B 1 740 ? 144.945 162.038 157.183 1.00 60.99  ? 740  SER B O   1 
ATOM   12522 C  CB  . SER B 1 740 ? 144.114 162.965 154.115 1.00 60.99  ? 740  SER B CB  1 
ATOM   12523 O  OG  . SER B 1 740 ? 145.017 163.959 154.567 1.00 60.99  ? 740  SER B OG  1 
ATOM   12524 N  N   . GLN B 1 741 ? 142.736 161.934 156.758 1.00 57.96  ? 741  GLN B N   1 
ATOM   12525 C  CA  . GLN B 1 741 ? 142.373 162.253 158.135 1.00 57.96  ? 741  GLN B CA  1 
ATOM   12526 C  C   . GLN B 1 741 ? 142.676 161.103 159.084 1.00 57.96  ? 741  GLN B C   1 
ATOM   12527 O  O   . GLN B 1 741 ? 142.665 161.293 160.305 1.00 57.96  ? 741  GLN B O   1 
ATOM   12528 C  CB  . GLN B 1 741 ? 140.892 162.625 158.213 1.00 57.96  ? 741  GLN B CB  1 
ATOM   12529 C  CG  . GLN B 1 741 ? 140.521 163.874 157.440 1.00 57.96  ? 741  GLN B CG  1 
ATOM   12530 C  CD  . GLN B 1 741 ? 141.051 165.134 158.085 1.00 57.96  ? 741  GLN B CD  1 
ATOM   12531 O  OE1 . GLN B 1 741 ? 142.013 165.732 157.606 1.00 57.96  ? 741  GLN B OE1 1 
ATOM   12532 N  NE2 . GLN B 1 741 ? 140.421 165.550 159.177 1.00 57.96  ? 741  GLN B NE2 1 
ATOM   12533 N  N   . VAL B 1 742 ? 142.923 159.906 158.549 1.00 55.39  ? 742  VAL B N   1 
ATOM   12534 C  CA  . VAL B 1 742 ? 143.283 158.741 159.358 1.00 55.39  ? 742  VAL B CA  1 
ATOM   12535 C  C   . VAL B 1 742 ? 144.358 159.084 160.387 1.00 55.39  ? 742  VAL B C   1 
ATOM   12536 O  O   . VAL B 1 742 ? 144.340 158.571 161.512 1.00 55.39  ? 742  VAL B O   1 
ATOM   12537 C  CB  . VAL B 1 742 ? 143.742 157.575 158.460 1.00 55.39  ? 742  VAL B CB  1 
ATOM   12538 C  CG1 . VAL B 1 742 ? 144.412 156.486 159.281 1.00 55.39  ? 742  VAL B CG1 1 
ATOM   12539 C  CG2 . VAL B 1 742 ? 142.562 156.998 157.704 1.00 55.39  ? 742  VAL B CG2 1 
ATOM   12540 N  N   . ALA B 1 743 ? 145.283 159.972 160.027 1.00 56.39  ? 743  ALA B N   1 
ATOM   12541 C  CA  . ALA B 1 743 ? 146.409 160.316 160.885 1.00 56.39  ? 743  ALA B CA  1 
ATOM   12542 C  C   . ALA B 1 743 ? 146.078 161.368 161.937 1.00 56.39  ? 743  ALA B C   1 
ATOM   12543 O  O   . ALA B 1 743 ? 146.946 161.698 162.751 1.00 56.39  ? 743  ALA B O   1 
ATOM   12544 C  CB  . ALA B 1 743 ? 147.590 160.800 160.037 1.00 56.39  ? 743  ALA B CB  1 
ATOM   12545 N  N   . ILE B 1 744 ? 144.857 161.912 161.936 1.00 51.31  ? 744  ILE B N   1 
ATOM   12546 C  CA  . ILE B 1 744 ? 144.495 162.923 162.937 1.00 51.31  ? 744  ILE B CA  1 
ATOM   12547 C  C   . ILE B 1 744 ? 144.592 162.390 164.360 1.00 51.31  ? 744  ILE B C   1 
ATOM   12548 O  O   . ILE B 1 744 ? 145.088 163.118 165.233 1.00 51.31  ? 744  ILE B O   1 
ATOM   12549 C  CB  . ILE B 1 744 ? 143.124 163.528 162.609 1.00 51.31  ? 744  ILE B CB  1 
ATOM   12550 C  CG1 . ILE B 1 744 ? 143.190 164.351 161.324 1.00 51.31  ? 744  ILE B CG1 1 
ATOM   12551 C  CG2 . ILE B 1 744 ? 142.632 164.392 163.757 1.00 51.31  ? 744  ILE B CG2 1 
ATOM   12552 C  CD1 . ILE B 1 744 ? 143.904 165.671 161.490 1.00 51.31  ? 744  ILE B CD1 1 
ATOM   12553 N  N   . PRO B 1 745 ? 144.133 161.159 164.688 1.00 49.28  ? 745  PRO B N   1 
ATOM   12554 C  CA  . PRO B 1 745 ? 144.325 160.644 166.054 1.00 49.28  ? 745  PRO B CA  1 
ATOM   12555 C  C   . PRO B 1 745 ? 145.751 160.760 166.578 1.00 49.28  ? 745  PRO B C   1 
ATOM   12556 O  O   . PRO B 1 745 ? 145.973 160.712 167.792 1.00 49.28  ? 745  PRO B O   1 
ATOM   12557 C  CB  . PRO B 1 745 ? 143.908 159.173 165.938 1.00 49.28  ? 745  PRO B CB  1 
ATOM   12558 C  CG  . PRO B 1 745 ? 143.018 159.097 164.752 1.00 49.28  ? 745  PRO B CG  1 
ATOM   12559 C  CD  . PRO B 1 745 ? 143.162 160.344 163.933 1.00 49.28  ? 745  PRO B CD  1 
ATOM   12560 N  N   . PHE B 1 746 ? 146.722 160.910 165.679 1.00 51.23  ? 746  PHE B N   1 
ATOM   12561 C  CA  . PHE B 1 746 ? 148.123 161.060 166.048 1.00 51.23  ? 746  PHE B CA  1 
ATOM   12562 C  C   . PHE B 1 746 ? 148.576 162.516 166.051 1.00 51.23  ? 746  PHE B C   1 
ATOM   12563 O  O   . PHE B 1 746 ? 149.779 162.778 166.136 1.00 51.23  ? 746  PHE B O   1 
ATOM   12564 C  CB  . PHE B 1 746 ? 149.009 160.242 165.104 1.00 51.23  ? 746  PHE B CB  1 
ATOM   12565 C  CG  . PHE B 1 746 ? 148.666 158.778 165.058 1.00 51.23  ? 746  PHE B CG  1 
ATOM   12566 C  CD1 . PHE B 1 746 ? 147.634 158.317 164.257 1.00 51.23  ? 746  PHE B CD1 1 
ATOM   12567 C  CD2 . PHE B 1 746 ? 149.377 157.862 165.815 1.00 51.23  ? 746  PHE B CD2 1 
ATOM   12568 C  CE1 . PHE B 1 746 ? 147.317 156.973 164.213 1.00 51.23  ? 746  PHE B CE1 1 
ATOM   12569 C  CE2 . PHE B 1 746 ? 149.064 156.515 165.773 1.00 51.23  ? 746  PHE B CE2 1 
ATOM   12570 C  CZ  . PHE B 1 746 ? 148.033 156.072 164.972 1.00 51.23  ? 746  PHE B CZ  1 
ATOM   12571 N  N   . ASP B 1 747 ? 147.644 163.463 165.966 1.00 57.29  ? 747  ASP B N   1 
ATOM   12572 C  CA  . ASP B 1 747 ? 147.986 164.875 165.892 1.00 57.29  ? 747  ASP B CA  1 
ATOM   12573 C  C   . ASP B 1 747 ? 148.530 165.377 167.229 1.00 57.29  ? 747  ASP B C   1 
ATOM   12574 O  O   . ASP B 1 747 ? 148.429 164.717 168.268 1.00 57.29  ? 747  ASP B O   1 
ATOM   12575 C  CB  . ASP B 1 747 ? 146.765 165.701 165.488 1.00 57.29  ? 747  ASP B CB  1 
ATOM   12576 C  CG  . ASP B 1 747 ? 147.135 167.026 164.855 1.00 57.29  ? 747  ASP B CG  1 
ATOM   12577 O  OD1 . ASP B 1 747 ? 148.270 167.497 165.074 1.00 57.29  ? 747  ASP B OD1 1 
ATOM   12578 O  OD2 . ASP B 1 747 ? 146.283 167.603 164.148 1.00 57.29  ? 747  ASP B OD2 1 
ATOM   12579 N  N   . ASN B 1 748 ? 149.117 166.568 167.188 1.00 63.04  ? 748  ASN B N   1 
ATOM   12580 C  CA  . ASN B 1 748 ? 149.569 167.258 168.385 1.00 63.04  ? 748  ASN B CA  1 
ATOM   12581 C  C   . ASN B 1 748 ? 148.519 168.266 168.834 1.00 63.04  ? 748  ASN B C   1 
ATOM   12582 O  O   . ASN B 1 748 ? 147.805 168.855 168.018 1.00 63.04  ? 748  ASN B O   1 
ATOM   12583 C  CB  . ASN B 1 748 ? 150.901 167.969 168.137 1.00 63.04  ? 748  ASN B CB  1 
ATOM   12584 C  CG  . ASN B 1 748 ? 152.041 167.003 167.889 1.00 63.04  ? 748  ASN B CG  1 
ATOM   12585 O  OD1 . ASN B 1 748 ? 152.135 165.956 168.530 1.00 63.04  ? 748  ASN B OD1 1 
ATOM   12586 N  ND2 . ASN B 1 748 ? 152.921 167.352 166.957 1.00 63.04  ? 748  ASN B ND2 1 
ATOM   12587 N  N   . VAL B 1 749 ? 148.431 168.458 170.147 1.00 61.89  ? 749  VAL B N   1 
ATOM   12588 C  CA  . VAL B 1 749 ? 147.439 169.336 170.757 1.00 61.89  ? 749  VAL B CA  1 
ATOM   12589 C  C   . VAL B 1 749 ? 148.169 170.428 171.524 1.00 61.89  ? 749  VAL B C   1 
ATOM   12590 O  O   . VAL B 1 749 ? 149.096 170.141 172.290 1.00 61.89  ? 749  VAL B O   1 
ATOM   12591 C  CB  . VAL B 1 749 ? 146.488 168.559 171.685 1.00 61.89  ? 749  VAL B CB  1 
ATOM   12592 C  CG1 . VAL B 1 749 ? 145.405 169.479 172.224 1.00 61.89  ? 749  VAL B CG1 1 
ATOM   12593 C  CG2 . VAL B 1 749 ? 145.875 167.380 170.948 1.00 61.89  ? 749  VAL B CG2 1 
ATOM   12594 N  N   . ASP B 1 750 ? 147.756 171.675 171.310 1.00 69.88  ? 750  ASP B N   1 
ATOM   12595 C  CA  . ASP B 1 750 ? 148.365 172.796 172.012 1.00 69.88  ? 750  ASP B CA  1 
ATOM   12596 C  C   . ASP B 1 750 ? 148.114 172.687 173.510 1.00 69.88  ? 750  ASP B C   1 
ATOM   12597 O  O   . ASP B 1 750 ? 147.072 172.192 173.949 1.00 69.88  ? 750  ASP B O   1 
ATOM   12598 C  CB  . ASP B 1 750 ? 147.809 174.119 171.486 1.00 69.88  ? 750  ASP B CB  1 
ATOM   12599 C  CG  . ASP B 1 750 ? 147.891 174.229 169.979 1.00 69.88  ? 750  ASP B CG  1 
ATOM   12600 O  OD1 . ASP B 1 750 ? 148.830 173.656 169.388 1.00 69.88  ? 750  ASP B OD1 1 
ATOM   12601 O  OD2 . ASP B 1 750 ? 147.016 174.894 169.387 1.00 69.88  ? 750  ASP B OD2 1 
ATOM   12602 N  N   . ASP B 1 751 ? 149.082 173.158 174.299 1.00 70.36  ? 751  ASP B N   1 
ATOM   12603 C  CA  . ASP B 1 751 ? 148.939 173.132 175.749 1.00 70.36  ? 751  ASP B CA  1 
ATOM   12604 C  C   . ASP B 1 751 ? 147.827 174.051 176.240 1.00 70.36  ? 751  ASP B C   1 
ATOM   12605 O  O   . ASP B 1 751 ? 147.395 173.917 177.389 1.00 70.36  ? 751  ASP B O   1 
ATOM   12606 C  CB  . ASP B 1 751 ? 150.260 173.514 176.417 1.00 70.36  ? 751  ASP B CB  1 
ATOM   12607 C  CG  . ASP B 1 751 ? 151.310 172.428 176.296 1.00 70.36  ? 751  ASP B CG  1 
ATOM   12608 O  OD1 . ASP B 1 751 ? 150.933 171.241 176.202 1.00 70.36  ? 751  ASP B OD1 1 
ATOM   12609 O  OD2 . ASP B 1 751 ? 152.514 172.761 176.296 1.00 70.36  ? 751  ASP B OD2 1 
ATOM   12610 N  N   . GLU B 1 752 ? 147.360 174.978 175.402 1.00 75.27  ? 752  GLU B N   1 
ATOM   12611 C  CA  . GLU B 1 752 ? 146.270 175.858 175.808 1.00 75.27  ? 752  GLU B CA  1 
ATOM   12612 C  C   . GLU B 1 752 ? 144.935 175.125 175.839 1.00 75.27  ? 752  GLU B C   1 
ATOM   12613 O  O   . GLU B 1 752 ? 144.083 175.426 176.682 1.00 75.27  ? 752  GLU B O   1 
ATOM   12614 C  CB  . GLU B 1 752 ? 146.194 177.063 174.870 1.00 75.27  ? 752  GLU B CB  1 
ATOM   12615 C  CG  . GLU B 1 752 ? 145.175 178.112 175.282 1.00 75.27  ? 752  GLU B CG  1 
ATOM   12616 C  CD  . GLU B 1 752 ? 145.176 179.314 174.360 1.00 75.27  ? 752  GLU B CD  1 
ATOM   12617 O  OE1 . GLU B 1 752 ? 145.948 179.312 173.378 1.00 75.27  ? 752  GLU B OE1 1 
ATOM   12618 O  OE2 . GLU B 1 752 ? 144.405 180.262 174.617 1.00 75.27  ? 752  GLU B OE2 1 
ATOM   12619 N  N   . GLN B 1 753 ? 144.736 174.162 174.935 1.00 67.23  ? 753  GLN B N   1 
ATOM   12620 C  CA  . GLN B 1 753 ? 143.475 173.430 174.898 1.00 67.23  ? 753  GLN B CA  1 
ATOM   12621 C  C   . GLN B 1 753 ? 143.372 172.419 176.034 1.00 67.23  ? 753  GLN B C   1 
ATOM   12622 O  O   . GLN B 1 753 ? 142.266 171.989 176.381 1.00 67.23  ? 753  GLN B O   1 
ATOM   12623 C  CB  . GLN B 1 753 ? 143.320 172.724 173.552 1.00 67.23  ? 753  GLN B CB  1 
ATOM   12624 C  CG  . GLN B 1 753 ? 143.423 173.649 172.352 1.00 67.23  ? 753  GLN B CG  1 
ATOM   12625 C  CD  . GLN B 1 753 ? 143.365 172.904 171.033 1.00 67.23  ? 753  GLN B CD  1 
ATOM   12626 O  OE1 . GLN B 1 753 ? 143.186 171.687 171.002 1.00 67.23  ? 753  GLN B OE1 1 
ATOM   12627 N  NE2 . GLN B 1 753 ? 143.528 173.631 169.934 1.00 67.23  ? 753  GLN B NE2 1 
ATOM   12628 N  N   . ILE B 1 754 ? 144.500 172.033 176.624 1.00 57.95  ? 754  ILE B N   1 
ATOM   12629 C  CA  . ILE B 1 754 ? 144.535 170.997 177.645 1.00 57.95  ? 754  ILE B CA  1 
ATOM   12630 C  C   . ILE B 1 754 ? 144.977 171.557 178.997 1.00 57.95  ? 754  ILE B C   1 
ATOM   12631 O  O   . ILE B 1 754 ? 145.309 170.796 179.903 1.00 57.95  ? 754  ILE B O   1 
ATOM   12632 C  CB  . ILE B 1 754 ? 145.429 169.825 177.212 1.00 57.95  ? 754  ILE B CB  1 
ATOM   12633 C  CG1 . ILE B 1 754 ? 146.847 170.323 176.930 1.00 57.95  ? 754  ILE B CG1 1 
ATOM   12634 C  CG2 . ILE B 1 754 ? 144.853 169.145 175.984 1.00 57.95  ? 754  ILE B CG2 1 
ATOM   12635 C  CD1 . ILE B 1 754 ? 147.892 169.234 176.940 1.00 57.95  ? 754  ILE B CD1 1 
ATOM   12636 N  N   . GLN B 1 755 ? 144.990 172.879 179.146 1.00 57.75  ? 755  GLN B N   1 
ATOM   12637 C  CA  . GLN B 1 755 ? 145.388 173.506 180.399 1.00 57.75  ? 755  GLN B CA  1 
ATOM   12638 C  C   . GLN B 1 755 ? 144.271 173.523 181.435 1.00 57.75  ? 755  GLN B C   1 
ATOM   12639 O  O   . GLN B 1 755 ? 144.547 173.730 182.621 1.00 57.75  ? 755  GLN B O   1 
ATOM   12640 C  CB  . GLN B 1 755 ? 145.868 174.939 180.136 1.00 57.75  ? 755  GLN B CB  1 
ATOM   12641 C  CG  . GLN B 1 755 ? 146.624 175.582 181.289 1.00 57.75  ? 755  GLN B CG  1 
ATOM   12642 C  CD  . GLN B 1 755 ? 147.081 176.992 180.971 1.00 57.75  ? 755  GLN B CD  1 
ATOM   12643 O  OE1 . GLN B 1 755 ? 146.791 177.525 179.900 1.00 57.75  ? 755  GLN B OE1 1 
ATOM   12644 N  NE2 . GLN B 1 755 ? 147.800 177.606 181.904 1.00 57.75  ? 755  GLN B NE2 1 
ATOM   12645 N  N   . LYS B 1 756 ? 143.032 173.295 181.024 1.00 48.57  ? 756  LYS B N   1 
ATOM   12646 C  CA  . LYS B 1 756 ? 141.877 173.341 181.904 1.00 48.57  ? 756  LYS B CA  1 
ATOM   12647 C  C   . LYS B 1 756 ? 141.012 172.120 181.632 1.00 48.57  ? 756  LYS B C   1 
ATOM   12648 O  O   . LYS B 1 756 ? 141.117 171.506 180.566 1.00 48.57  ? 756  LYS B O   1 
ATOM   12649 C  CB  . LYS B 1 756 ? 141.063 174.624 181.692 1.00 48.57  ? 756  LYS B CB  1 
ATOM   12650 C  CG  . LYS B 1 756 ? 141.802 175.895 182.070 1.00 48.57  ? 756  LYS B CG  1 
ATOM   12651 C  CD  . LYS B 1 756 ? 141.852 176.077 183.576 1.00 48.57  ? 756  LYS B CD  1 
ATOM   12652 C  CE  . LYS B 1 756 ? 143.236 176.506 184.033 1.00 48.57  ? 756  LYS B CE  1 
ATOM   12653 N  NZ  . LYS B 1 756 ? 143.399 176.378 185.507 1.00 48.57  ? 756  LYS B NZ  1 
ATOM   12654 N  N   . PRO B 1 757 ? 140.165 171.732 182.587 1.00 45.76  ? 757  PRO B N   1 
ATOM   12655 C  CA  . PRO B 1 757 ? 139.244 170.618 182.335 1.00 45.76  ? 757  PRO B CA  1 
ATOM   12656 C  C   . PRO B 1 757 ? 138.362 170.897 181.128 1.00 45.76  ? 757  PRO B C   1 
ATOM   12657 O  O   . PRO B 1 757 ? 137.901 172.021 180.917 1.00 45.76  ? 757  PRO B O   1 
ATOM   12658 C  CB  . PRO B 1 757 ? 138.424 170.541 183.626 1.00 45.76  ? 757  PRO B CB  1 
ATOM   12659 C  CG  . PRO B 1 757 ? 139.335 171.082 184.665 1.00 45.76  ? 757  PRO B CG  1 
ATOM   12660 C  CD  . PRO B 1 757 ? 140.104 172.183 183.988 1.00 45.76  ? 757  PRO B CD  1 
ATOM   12661 N  N   . GLN B 1 758 ? 138.134 169.858 180.332 1.00 49.23  ? 758  GLN B N   1 
ATOM   12662 C  CA  . GLN B 1 758 ? 137.400 169.991 179.083 1.00 49.23  ? 758  GLN B CA  1 
ATOM   12663 C  C   . GLN B 1 758 ? 135.899 169.890 179.319 1.00 49.23  ? 758  GLN B C   1 
ATOM   12664 O  O   . GLN B 1 758 ? 135.429 169.023 180.061 1.00 49.23  ? 758  GLN B O   1 
ATOM   12665 C  CB  . GLN B 1 758 ? 137.840 168.920 178.085 1.00 49.23  ? 758  GLN B CB  1 
ATOM   12666 C  CG  . GLN B 1 758 ? 139.299 169.013 177.680 1.00 49.23  ? 758  GLN B CG  1 
ATOM   12667 C  CD  . GLN B 1 758 ? 139.753 167.816 176.871 1.00 49.23  ? 758  GLN B CD  1 
ATOM   12668 O  OE1 . GLN B 1 758 ? 139.273 166.701 177.068 1.00 49.23  ? 758  GLN B OE1 1 
ATOM   12669 N  NE2 . GLN B 1 758 ? 140.681 168.044 175.950 1.00 49.23  ? 758  GLN B NE2 1 
ATOM   12670 N  N   . ARG B 1 759 ? 135.154 170.786 178.682 1.00 52.91  ? 759  ARG B N   1 
ATOM   12671 C  CA  . ARG B 1 759 ? 133.700 170.736 178.650 1.00 52.91  ? 759  ARG B CA  1 
ATOM   12672 C  C   . ARG B 1 759 ? 133.264 170.585 177.201 1.00 52.91  ? 759  ARG B C   1 
ATOM   12673 O  O   . ARG B 1 759 ? 133.685 171.364 176.340 1.00 52.91  ? 759  ARG B O   1 
ATOM   12674 C  CB  . ARG B 1 759 ? 133.085 171.992 179.271 1.00 52.91  ? 759  ARG B CB  1 
ATOM   12675 C  CG  . ARG B 1 759 ? 133.543 172.263 180.693 1.00 52.91  ? 759  ARG B CG  1 
ATOM   12676 C  CD  . ARG B 1 759 ? 133.056 171.184 181.645 1.00 52.91  ? 759  ARG B CD  1 
ATOM   12677 N  NE  . ARG B 1 759 ? 133.703 171.279 182.948 1.00 52.91  ? 759  ARG B NE  1 
ATOM   12678 C  CZ  . ARG B 1 759 ? 133.357 170.566 184.011 1.00 52.91  ? 759  ARG B CZ  1 
ATOM   12679 N  NH1 . ARG B 1 759 ? 132.356 169.702 183.967 1.00 52.91  ? 759  ARG B NH1 1 
ATOM   12680 N  NH2 . ARG B 1 759 ? 134.030 170.726 185.147 1.00 52.91  ? 759  ARG B NH2 1 
ATOM   12681 N  N   . TRP B 1 760 ? 132.429 169.587 176.935 1.00 51.65  ? 760  TRP B N   1 
ATOM   12682 C  CA  . TRP B 1 760 ? 132.025 169.241 175.579 1.00 51.65  ? 760  TRP B CA  1 
ATOM   12683 C  C   . TRP B 1 760 ? 130.590 169.696 175.358 1.00 51.65  ? 760  TRP B C   1 
ATOM   12684 O  O   . TRP B 1 760 ? 129.682 169.271 176.080 1.00 51.65  ? 760  TRP B O   1 
ATOM   12685 C  CB  . TRP B 1 760 ? 132.166 167.738 175.338 1.00 51.65  ? 760  TRP B CB  1 
ATOM   12686 C  CG  . TRP B 1 760 ? 131.655 167.279 174.007 1.00 51.65  ? 760  TRP B CG  1 
ATOM   12687 C  CD1 . TRP B 1 760 ? 131.603 168.004 172.851 1.00 51.65  ? 760  TRP B CD1 1 
ATOM   12688 C  CD2 . TRP B 1 760 ? 131.142 165.981 173.689 1.00 51.65  ? 760  TRP B CD2 1 
ATOM   12689 N  NE1 . TRP B 1 760 ? 131.079 167.240 171.837 1.00 51.65  ? 760  TRP B NE1 1 
ATOM   12690 C  CE2 . TRP B 1 760 ? 130.789 165.994 172.325 1.00 51.65  ? 760  TRP B CE2 1 
ATOM   12691 C  CE3 . TRP B 1 760 ? 130.943 164.810 174.426 1.00 51.65  ? 760  TRP B CE3 1 
ATOM   12692 C  CZ2 . TRP B 1 760 ? 130.249 164.883 171.685 1.00 51.65  ? 760  TRP B CZ2 1 
ATOM   12693 C  CZ3 . TRP B 1 760 ? 130.407 163.709 173.788 1.00 51.65  ? 760  TRP B CZ3 1 
ATOM   12694 C  CH2 . TRP B 1 760 ? 130.067 163.753 172.431 1.00 51.65  ? 760  TRP B CH2 1 
ATOM   12695 N  N   . ASN B 1 761 ? 130.393 170.555 174.366 1.00 53.92  ? 761  ASN B N   1 
ATOM   12696 C  CA  . ASN B 1 761 ? 129.066 171.050 174.004 1.00 53.92  ? 761  ASN B CA  1 
ATOM   12697 C  C   . ASN B 1 761 ? 128.729 170.594 172.593 1.00 53.92  ? 761  ASN B C   1 
ATOM   12698 O  O   . ASN B 1 761 ? 129.316 171.111 171.624 1.00 53.92  ? 761  ASN B O   1 
ATOM   12699 C  CB  . ASN B 1 761 ? 129.006 172.573 174.104 1.00 53.92  ? 761  ASN B CB  1 
ATOM   12700 C  CG  . ASN B 1 761 ? 127.591 173.090 174.262 1.00 53.92  ? 761  ASN B CG  1 
ATOM   12701 O  OD1 . ASN B 1 761 ? 126.644 172.313 174.378 1.00 53.92  ? 761  ASN B OD1 1 
ATOM   12702 N  ND2 . ASN B 1 761 ? 127.441 174.409 174.271 1.00 53.92  ? 761  ASN B ND2 1 
ATOM   12703 N  N   . PRO B 1 762 ? 127.816 169.636 172.421 1.00 53.16  ? 762  PRO B N   1 
ATOM   12704 C  CA  . PRO B 1 762 ? 127.486 169.168 171.065 1.00 53.16  ? 762  PRO B CA  1 
ATOM   12705 C  C   . PRO B 1 762 ? 126.945 170.255 170.156 1.00 53.16  ? 762  PRO B C   1 
ATOM   12706 O  O   . PRO B 1 762 ? 127.105 170.154 168.933 1.00 53.16  ? 762  PRO B O   1 
ATOM   12707 C  CB  . PRO B 1 762 ? 126.435 168.079 171.319 1.00 53.16  ? 762  PRO B CB  1 
ATOM   12708 C  CG  . PRO B 1 762 ? 126.694 167.628 172.722 1.00 53.16  ? 762  PRO B CG  1 
ATOM   12709 C  CD  . PRO B 1 762 ? 127.108 168.867 173.458 1.00 53.16  ? 762  PRO B CD  1 
ATOM   12710 N  N   . ALA B 1 763 ? 126.305 171.289 170.706 1.00 58.13  ? 763  ALA B N   1 
ATOM   12711 C  CA  . ALA B 1 763 ? 125.780 172.366 169.876 1.00 58.13  ? 763  ALA B CA  1 
ATOM   12712 C  C   . ALA B 1 763 ? 126.882 173.229 169.277 1.00 58.13  ? 763  ALA B C   1 
ATOM   12713 O  O   . ALA B 1 763 ? 126.622 173.965 168.319 1.00 58.13  ? 763  ALA B O   1 
ATOM   12714 C  CB  . ALA B 1 763 ? 124.821 173.238 170.687 1.00 58.13  ? 763  ALA B CB  1 
ATOM   12715 N  N   . ASP B 1 764 ? 128.101 173.160 169.818 1.00 61.69  ? 764  ASP B N   1 
ATOM   12716 C  CA  . ASP B 1 764 ? 129.201 173.946 169.267 1.00 61.69  ? 764  ASP B CA  1 
ATOM   12717 C  C   . ASP B 1 764 ? 129.590 173.469 167.874 1.00 61.69  ? 764  ASP B C   1 
ATOM   12718 O  O   . ASP B 1 764 ? 130.103 174.258 167.071 1.00 61.69  ? 764  ASP B O   1 
ATOM   12719 C  CB  . ASP B 1 764 ? 130.407 173.887 170.205 1.00 61.69  ? 764  ASP B CB  1 
ATOM   12720 C  CG  . ASP B 1 764 ? 131.274 175.128 170.119 1.00 61.69  ? 764  ASP B CG  1 
ATOM   12721 O  OD1 . ASP B 1 764 ? 131.166 175.866 169.118 1.00 61.69  ? 764  ASP B OD1 1 
ATOM   12722 O  OD2 . ASP B 1 764 ? 132.066 175.366 171.055 1.00 61.69  ? 764  ASP B OD2 1 
ATOM   12723 N  N   . LEU B 1 765 ? 129.363 172.188 167.572 1.00 54.07  ? 765  LEU B N   1 
ATOM   12724 C  CA  . LEU B 1 765 ? 129.690 171.670 166.248 1.00 54.07  ? 765  LEU B CA  1 
ATOM   12725 C  C   . LEU B 1 765 ? 128.856 172.348 165.169 1.00 54.07  ? 765  LEU B C   1 
ATOM   12726 O  O   . LEU B 1 765 ? 129.361 172.651 164.082 1.00 54.07  ? 765  LEU B O   1 
ATOM   12727 C  CB  . LEU B 1 765 ? 129.488 170.156 166.211 1.00 54.07  ? 765  LEU B CB  1 
ATOM   12728 C  CG  . LEU B 1 765 ? 129.613 169.500 164.836 1.00 54.07  ? 765  LEU B CG  1 
ATOM   12729 C  CD1 . LEU B 1 765 ? 131.031 169.631 164.311 1.00 54.07  ? 765  LEU B CD1 1 
ATOM   12730 C  CD2 . LEU B 1 765 ? 129.197 168.043 164.896 1.00 54.07  ? 765  LEU B CD2 1 
ATOM   12731 N  N   . GLY B 1 766 ? 127.574 172.587 165.448 1.00 59.72  ? 766  GLY B N   1 
ATOM   12732 C  CA  . GLY B 1 766 ? 126.738 173.283 164.483 1.00 59.72  ? 766  GLY B CA  1 
ATOM   12733 C  C   . GLY B 1 766 ? 127.216 174.696 164.213 1.00 59.72  ? 766  GLY B C   1 
ATOM   12734 O  O   . GLY B 1 766 ? 127.251 175.141 163.063 1.00 59.72  ? 766  GLY B O   1 
ATOM   12735 N  N   . ARG B 1 767 ? 127.592 175.420 165.269 1.00 64.60  ? 767  ARG B N   1 
ATOM   12736 C  CA  . ARG B 1 767 ? 128.127 176.765 165.088 1.00 64.60  ? 767  ARG B CA  1 
ATOM   12737 C  C   . ARG B 1 767 ? 129.424 176.735 164.291 1.00 64.60  ? 767  ARG B C   1 
ATOM   12738 O  O   . ARG B 1 767 ? 129.640 177.575 163.410 1.00 64.60  ? 767  ARG B O   1 
ATOM   12739 C  CB  . ARG B 1 767 ? 128.347 177.430 166.446 1.00 64.60  ? 767  ARG B CB  1 
ATOM   12740 C  CG  . ARG B 1 767 ? 127.066 177.759 167.192 1.00 64.60  ? 767  ARG B CG  1 
ATOM   12741 C  CD  . ARG B 1 767 ? 127.292 178.866 168.206 1.00 64.60  ? 767  ARG B CD  1 
ATOM   12742 N  NE  . ARG B 1 767 ? 128.616 178.786 168.810 1.00 64.60  ? 767  ARG B NE  1 
ATOM   12743 C  CZ  . ARG B 1 767 ? 128.885 178.153 169.944 1.00 64.60  ? 767  ARG B CZ  1 
ATOM   12744 N  NH1 . ARG B 1 767 ? 127.942 177.525 170.626 1.00 64.60  ? 767  ARG B NH1 1 
ATOM   12745 N  NH2 . ARG B 1 767 ? 130.133 178.149 170.404 1.00 64.60  ? 767  ARG B NH2 1 
ATOM   12746 N  N   . PHE B 1 768 ? 130.298 175.767 164.583 1.00 62.75  ? 768  PHE B N   1 
ATOM   12747 C  CA  . PHE B 1 768 ? 131.548 175.647 163.839 1.00 62.75  ? 768  PHE B CA  1 
ATOM   12748 C  C   . PHE B 1 768 ? 131.285 175.384 162.362 1.00 62.75  ? 768  PHE B C   1 
ATOM   12749 O  O   . PHE B 1 768 ? 131.920 175.991 161.491 1.00 62.75  ? 768  PHE B O   1 
ATOM   12750 C  CB  . PHE B 1 768 ? 132.404 174.534 164.442 1.00 62.75  ? 768  PHE B CB  1 
ATOM   12751 C  CG  . PHE B 1 768 ? 133.831 174.539 163.973 1.00 62.75  ? 768  PHE B CG  1 
ATOM   12752 C  CD1 . PHE B 1 768 ? 134.194 173.896 162.801 1.00 62.75  ? 768  PHE B CD1 1 
ATOM   12753 C  CD2 . PHE B 1 768 ? 134.812 175.178 164.711 1.00 62.75  ? 768  PHE B CD2 1 
ATOM   12754 C  CE1 . PHE B 1 768 ? 135.507 173.898 162.372 1.00 62.75  ? 768  PHE B CE1 1 
ATOM   12755 C  CE2 . PHE B 1 768 ? 136.128 175.182 164.286 1.00 62.75  ? 768  PHE B CE2 1 
ATOM   12756 C  CZ  . PHE B 1 768 ? 136.475 174.541 163.116 1.00 62.75  ? 768  PHE B CZ  1 
ATOM   12757 N  N   . MET B 1 769 ? 130.350 174.479 162.062 1.00 62.71  ? 769  MET B N   1 
ATOM   12758 C  CA  . MET B 1 769 ? 130.019 174.182 160.673 1.00 62.71  ? 769  MET B CA  1 
ATOM   12759 C  C   . MET B 1 769 ? 129.450 175.408 159.971 1.00 62.71  ? 769  MET B C   1 
ATOM   12760 O  O   . MET B 1 769 ? 129.845 175.735 158.847 1.00 62.71  ? 769  MET B O   1 
ATOM   12761 C  CB  . MET B 1 769 ? 129.027 173.020 160.610 1.00 62.71  ? 769  MET B CB  1 
ATOM   12762 C  CG  . MET B 1 769 ? 129.607 171.675 161.004 1.00 62.71  ? 769  MET B CG  1 
ATOM   12763 S  SD  . MET B 1 769 ? 128.327 170.424 161.223 1.00 62.71  ? 769  MET B SD  1 
ATOM   12764 C  CE  . MET B 1 769 ? 127.372 170.651 159.727 1.00 62.71  ? 769  MET B CE  1 
ATOM   12765 N  N   . ILE B 1 770 ? 128.521 176.105 160.629 1.00 65.35  ? 770  ILE B N   1 
ATOM   12766 C  CA  . ILE B 1 770 ? 127.913 177.290 160.029 1.00 65.35  ? 770  ILE B CA  1 
ATOM   12767 C  C   . ILE B 1 770 ? 128.971 178.354 159.769 1.00 65.35  ? 770  ILE B C   1 
ATOM   12768 O  O   . ILE B 1 770 ? 128.930 179.059 158.753 1.00 65.35  ? 770  ILE B O   1 
ATOM   12769 C  CB  . ILE B 1 770 ? 126.779 177.818 160.929 1.00 65.35  ? 770  ILE B CB  1 
ATOM   12770 C  CG1 . ILE B 1 770 ? 125.581 176.867 160.886 1.00 65.35  ? 770  ILE B CG1 1 
ATOM   12771 C  CG2 . ILE B 1 770 ? 126.358 179.217 160.510 1.00 65.35  ? 770  ILE B CG2 1 
ATOM   12772 C  CD1 . ILE B 1 770 ? 124.983 176.700 159.508 1.00 65.35  ? 770  ILE B CD1 1 
ATOM   12773 N  N   . PHE B 1 771 ? 129.945 178.474 160.671 1.00 70.03  ? 771  PHE B N   1 
ATOM   12774 C  CA  . PHE B 1 771 ? 130.966 179.503 160.519 1.00 70.03  ? 771  PHE B CA  1 
ATOM   12775 C  C   . PHE B 1 771 ? 131.960 179.152 159.418 1.00 70.03  ? 771  PHE B C   1 
ATOM   12776 O  O   . PHE B 1 771 ? 132.404 180.035 158.675 1.00 70.03  ? 771  PHE B O   1 
ATOM   12777 C  CB  . PHE B 1 771 ? 131.686 179.714 161.849 1.00 70.03  ? 771  PHE B CB  1 
ATOM   12778 C  CG  . PHE B 1 771 ? 132.499 180.973 161.905 1.00 70.03  ? 771  PHE B CG  1 
ATOM   12779 C  CD1 . PHE B 1 771 ? 131.915 182.172 162.275 1.00 70.03  ? 771  PHE B CD1 1 
ATOM   12780 C  CD2 . PHE B 1 771 ? 133.847 180.957 161.595 1.00 70.03  ? 771  PHE B CD2 1 
ATOM   12781 C  CE1 . PHE B 1 771 ? 132.660 183.333 162.331 1.00 70.03  ? 771  PHE B CE1 1 
ATOM   12782 C  CE2 . PHE B 1 771 ? 134.596 182.113 161.649 1.00 70.03  ? 771  PHE B CE2 1 
ATOM   12783 C  CZ  . PHE B 1 771 ? 134.003 183.303 162.017 1.00 70.03  ? 771  PHE B CZ  1 
ATOM   12784 N  N   . PHE B 1 772 ? 132.327 177.876 159.293 1.00 67.63  ? 772  PHE B N   1 
ATOM   12785 C  CA  . PHE B 1 772 ? 133.409 177.484 158.398 1.00 67.63  ? 772  PHE B CA  1 
ATOM   12786 C  C   . PHE B 1 772 ? 132.941 176.849 157.092 1.00 67.63  ? 772  PHE B C   1 
ATOM   12787 O  O   . PHE B 1 772 ? 133.781 176.386 156.315 1.00 67.63  ? 772  PHE B O   1 
ATOM   12788 C  CB  . PHE B 1 772 ? 134.363 176.529 159.122 1.00 67.63  ? 772  PHE B CB  1 
ATOM   12789 C  CG  . PHE B 1 772 ? 135.377 177.228 159.981 1.00 67.63  ? 772  PHE B CG  1 
ATOM   12790 C  CD1 . PHE B 1 772 ? 136.581 177.654 159.447 1.00 67.63  ? 772  PHE B CD1 1 
ATOM   12791 C  CD2 . PHE B 1 772 ? 135.123 177.466 161.321 1.00 67.63  ? 772  PHE B CD2 1 
ATOM   12792 C  CE1 . PHE B 1 772 ? 137.515 178.299 160.235 1.00 67.63  ? 772  PHE B CE1 1 
ATOM   12793 C  CE2 . PHE B 1 772 ? 136.053 178.110 162.113 1.00 67.63  ? 772  PHE B CE2 1 
ATOM   12794 C  CZ  . PHE B 1 772 ? 137.251 178.528 161.569 1.00 67.63  ? 772  PHE B CZ  1 
ATOM   12795 N  N   . GLY B 1 773 ? 131.638 176.811 156.826 1.00 71.38  ? 773  GLY B N   1 
ATOM   12796 C  CA  . GLY B 1 773 ? 131.146 176.315 155.560 1.00 71.38  ? 773  GLY B CA  1 
ATOM   12797 C  C   . GLY B 1 773 ? 131.215 177.325 154.428 1.00 71.38  ? 773  GLY B C   1 
ATOM   12798 O  O   . GLY B 1 773 ? 131.836 177.084 153.384 1.00 71.38  ? 773  GLY B O   1 
ATOM   12799 N  N   . PRO B 1 774 ? 130.563 178.478 154.605 1.00 76.70  ? 774  PRO B N   1 
ATOM   12800 C  CA  . PRO B 1 774 ? 130.602 179.508 153.554 1.00 76.70  ? 774  PRO B CA  1 
ATOM   12801 C  C   . PRO B 1 774 ? 132.003 179.978 153.210 1.00 76.70  ? 774  PRO B C   1 
ATOM   12802 O  O   . PRO B 1 774 ? 132.213 180.475 152.097 1.00 76.70  ? 774  PRO B O   1 
ATOM   12803 C  CB  . PRO B 1 774 ? 129.759 180.642 154.148 1.00 76.70  ? 774  PRO B CB  1 
ATOM   12804 C  CG  . PRO B 1 774 ? 128.800 179.945 155.044 1.00 76.70  ? 774  PRO B CG  1 
ATOM   12805 C  CD  . PRO B 1 774 ? 129.565 178.796 155.642 1.00 76.70  ? 774  PRO B CD  1 
ATOM   12806 N  N   . ILE B 1 775 ? 132.949 179.838 154.131 1.00 74.57  ? 775  ILE B N   1 
ATOM   12807 C  CA  . ILE B 1 775 ? 134.312 180.256 153.843 1.00 74.57  ? 775  ILE B CA  1 
ATOM   12808 C  C   . ILE B 1 775 ? 134.806 179.457 152.646 1.00 74.57  ? 775  ILE B C   1 
ATOM   12809 O  O   . ILE B 1 775 ? 135.270 180.020 151.656 1.00 74.57  ? 775  ILE B O   1 
ATOM   12810 C  CB  . ILE B 1 775 ? 135.250 180.048 155.041 1.00 74.57  ? 775  ILE B CB  1 
ATOM   12811 C  CG1 . ILE B 1 775 ? 134.856 180.984 156.182 1.00 74.57  ? 775  ILE B CG1 1 
ATOM   12812 C  CG2 . ILE B 1 775 ? 136.691 180.299 154.632 1.00 74.57  ? 775  ILE B CG2 1 
ATOM   12813 C  CD1 . ILE B 1 775 ? 135.860 181.024 157.312 1.00 74.57  ? 775  ILE B CD1 1 
ATOM   12814 N  N   . SER B 1 776 ? 134.705 178.136 152.749 1.00 75.90  ? 776  SER B N   1 
ATOM   12815 C  CA  . SER B 1 776 ? 135.106 177.251 151.666 1.00 75.90  ? 776  SER B CA  1 
ATOM   12816 C  C   . SER B 1 776 ? 134.224 177.477 150.440 1.00 75.90  ? 776  SER B C   1 
ATOM   12817 O  O   . SER B 1 776 ? 134.701 177.466 149.307 1.00 75.90  ? 776  SER B O   1 
ATOM   12818 C  CB  . SER B 1 776 ? 135.021 175.794 152.111 1.00 75.90  ? 776  SER B CB  1 
ATOM   12819 O  OG  . SER B 1 776 ? 133.714 175.484 152.556 1.00 75.90  ? 776  SER B OG  1 
ATOM   12820 N  N   . SER B 1 777 ? 132.932 177.676 150.679 1.00 77.19  ? 777  SER B N   1 
ATOM   12821 C  CA  . SER B 1 777 ? 131.967 177.900 149.607 1.00 77.19  ? 777  SER B CA  1 
ATOM   12822 C  C   . SER B 1 777 ? 132.364 179.052 148.689 1.00 77.19  ? 777  SER B C   1 
ATOM   12823 O  O   . SER B 1 777 ? 132.281 178.931 147.468 1.00 77.19  ? 777  SER B O   1 
ATOM   12824 C  CB  . SER B 1 777 ? 130.577 178.164 150.187 1.00 77.19  ? 777  SER B CB  1 
ATOM   12825 O  OG  . SER B 1 777 ? 130.136 177.071 150.971 1.00 77.19  ? 777  SER B OG  1 
ATOM   12826 N  N   . ILE B 1 778 ? 132.783 180.167 149.282 1.00 79.26  ? 778  ILE B N   1 
ATOM   12827 C  CA  . ILE B 1 778 ? 133.184 181.340 148.508 1.00 79.26  ? 778  ILE B CA  1 
ATOM   12828 C  C   . ILE B 1 778 ? 134.259 180.965 147.494 1.00 79.26  ? 778  ILE B C   1 
ATOM   12829 O  O   . ILE B 1 778 ? 134.176 181.315 146.310 1.00 79.26  ? 778  ILE B O   1 
ATOM   12830 C  CB  . ILE B 1 778 ? 133.657 182.464 149.447 1.00 79.26  ? 778  ILE B CB  1 
ATOM   12831 C  CG1 . ILE B 1 778 ? 132.456 183.164 150.083 1.00 79.26  ? 778  ILE B CG1 1 
ATOM   12832 C  CG2 . ILE B 1 778 ? 134.523 183.465 148.697 1.00 79.26  ? 778  ILE B CG2 1 
ATOM   12833 C  CD1 . ILE B 1 778 ? 132.829 184.156 151.162 1.00 79.26  ? 778  ILE B CD1 1 
ATOM   12834 N  N   . PHE B 1 779 ? 135.276 180.228 147.936 1.00 79.21  ? 779  PHE B N   1 
ATOM   12835 C  CA  . PHE B 1 779 ? 136.331 179.813 147.023 1.00 79.21  ? 779  PHE B CA  1 
ATOM   12836 C  C   . PHE B 1 779 ? 135.875 178.727 146.059 1.00 79.21  ? 779  PHE B C   1 
ATOM   12837 O  O   . PHE B 1 779 ? 136.399 178.653 144.942 1.00 79.21  ? 779  PHE B O   1 
ATOM   12838 C  CB  . PHE B 1 779 ? 137.556 179.359 147.814 1.00 79.21  ? 779  PHE B CB  1 
ATOM   12839 C  CG  . PHE B 1 779 ? 138.256 180.483 148.517 1.00 79.21  ? 779  PHE B CG  1 
ATOM   12840 C  CD1 . PHE B 1 779 ? 139.283 181.174 147.896 1.00 79.21  ? 779  PHE B CD1 1 
ATOM   12841 C  CD2 . PHE B 1 779 ? 137.868 180.870 149.788 1.00 79.21  ? 779  PHE B CD2 1 
ATOM   12842 C  CE1 . PHE B 1 779 ? 139.921 182.218 148.537 1.00 79.21  ? 779  PHE B CE1 1 
ATOM   12843 C  CE2 . PHE B 1 779 ? 138.502 181.911 150.432 1.00 79.21  ? 779  PHE B CE2 1 
ATOM   12844 C  CZ  . PHE B 1 779 ? 139.527 182.590 149.806 1.00 79.21  ? 779  PHE B CZ  1 
ATOM   12845 N  N   . ASP B 1 780 ? 134.897 177.904 146.444 1.00 82.79  ? 780  ASP B N   1 
ATOM   12846 C  CA  . ASP B 1 780 ? 134.298 176.991 145.475 1.00 82.79  ? 780  ASP B CA  1 
ATOM   12847 C  C   . ASP B 1 780 ? 133.603 177.762 144.357 1.00 82.79  ? 780  ASP B C   1 
ATOM   12848 O  O   . ASP B 1 780 ? 133.723 177.407 143.178 1.00 82.79  ? 780  ASP B O   1 
ATOM   12849 C  CB  . ASP B 1 780 ? 133.317 176.052 146.176 1.00 82.79  ? 780  ASP B CB  1 
ATOM   12850 C  CG  . ASP B 1 780 ? 133.998 174.829 146.755 1.00 82.79  ? 780  ASP B CG  1 
ATOM   12851 O  OD1 . ASP B 1 780 ? 134.951 174.325 146.124 1.00 82.79  ? 780  ASP B OD1 1 
ATOM   12852 O  OD2 . ASP B 1 780 ? 133.585 174.375 147.842 1.00 82.79  ? 780  ASP B OD2 1 
ATOM   12853 N  N   . ILE B 1 781 ? 132.880 178.826 144.710 1.00 82.28  ? 781  ILE B N   1 
ATOM   12854 C  CA  . ILE B 1 781 ? 132.239 179.670 143.705 1.00 82.28  ? 781  ILE B CA  1 
ATOM   12855 C  C   . ILE B 1 781 ? 133.287 180.354 142.834 1.00 82.28  ? 781  ILE B C   1 
ATOM   12856 O  O   . ILE B 1 781 ? 133.110 180.495 141.617 1.00 82.28  ? 781  ILE B O   1 
ATOM   12857 C  CB  . ILE B 1 781 ? 131.308 180.691 144.384 1.00 82.28  ? 781  ILE B CB  1 
ATOM   12858 C  CG1 . ILE B 1 781 ? 130.090 179.985 144.983 1.00 82.28  ? 781  ILE B CG1 1 
ATOM   12859 C  CG2 . ILE B 1 781 ? 130.866 181.762 143.400 1.00 82.28  ? 781  ILE B CG2 1 
ATOM   12860 C  CD1 . ILE B 1 781 ? 129.498 180.701 146.177 1.00 82.28  ? 781  ILE B CD1 1 
ATOM   12861 N  N   . LEU B 1 782 ? 134.387 180.803 143.442 1.00 82.66  ? 782  LEU B N   1 
ATOM   12862 C  CA  . LEU B 1 782 ? 135.463 181.414 142.666 1.00 82.66  ? 782  LEU B CA  1 
ATOM   12863 C  C   . LEU B 1 782 ? 136.058 180.425 141.669 1.00 82.66  ? 782  LEU B C   1 
ATOM   12864 O  O   . LEU B 1 782 ? 136.317 180.777 140.513 1.00 82.66  ? 782  LEU B O   1 
ATOM   12865 C  CB  . LEU B 1 782 ? 136.550 181.950 143.598 1.00 82.66  ? 782  LEU B CB  1 
ATOM   12866 C  CG  . LEU B 1 782 ? 136.201 183.166 144.457 1.00 82.66  ? 782  LEU B CG  1 
ATOM   12867 C  CD1 . LEU B 1 782 ? 137.468 183.867 144.918 1.00 82.66  ? 782  LEU B CD1 1 
ATOM   12868 C  CD2 . LEU B 1 782 ? 135.305 184.129 143.695 1.00 82.66  ? 782  LEU B CD2 1 
ATOM   12869 N  N   . THR B 1 783 ? 136.282 179.182 142.101 1.00 83.92  ? 783  THR B N   1 
ATOM   12870 C  CA  . THR B 1 783 ? 136.787 178.158 141.193 1.00 83.92  ? 783  THR B CA  1 
ATOM   12871 C  C   . THR B 1 783 ? 135.783 177.864 140.083 1.00 83.92  ? 783  THR B C   1 
ATOM   12872 O  O   . THR B 1 783 ? 136.169 177.642 138.928 1.00 83.92  ? 783  THR B O   1 
ATOM   12873 C  CB  . THR B 1 783 ? 137.121 176.887 141.975 1.00 83.92  ? 783  THR B CB  1 
ATOM   12874 O  OG1 . THR B 1 783 ? 138.092 177.192 142.982 1.00 83.92  ? 783  THR B OG1 1 
ATOM   12875 C  CG2 . THR B 1 783 ? 137.685 175.822 141.051 1.00 83.92  ? 783  THR B CG2 1 
ATOM   12876 N  N   . PHE B 1 784 ? 134.491 177.857 140.418 1.00 84.17  ? 784  PHE B N   1 
ATOM   12877 C  CA  . PHE B 1 784 ? 133.457 177.663 139.405 1.00 84.17  ? 784  PHE B CA  1 
ATOM   12878 C  C   . PHE B 1 784 ? 133.501 178.769 138.359 1.00 84.17  ? 784  PHE B C   1 
ATOM   12879 O  O   . PHE B 1 784 ? 133.417 178.505 137.155 1.00 84.17  ? 784  PHE B O   1 
ATOM   12880 C  CB  . PHE B 1 784 ? 132.083 177.604 140.070 1.00 84.17  ? 784  PHE B CB  1 
ATOM   12881 C  CG  . PHE B 1 784 ? 131.834 176.339 140.834 1.00 84.17  ? 784  PHE B CG  1 
ATOM   12882 C  CD1 . PHE B 1 784 ? 132.543 175.188 140.540 1.00 84.17  ? 784  PHE B CD1 1 
ATOM   12883 C  CD2 . PHE B 1 784 ? 130.902 176.303 141.855 1.00 84.17  ? 784  PHE B CD2 1 
ATOM   12884 C  CE1 . PHE B 1 784 ? 132.316 174.023 141.241 1.00 84.17  ? 784  PHE B CE1 1 
ATOM   12885 C  CE2 . PHE B 1 784 ? 130.674 175.141 142.562 1.00 84.17  ? 784  PHE B CE2 1 
ATOM   12886 C  CZ  . PHE B 1 784 ? 131.382 174.000 142.255 1.00 84.17  ? 784  PHE B CZ  1 
ATOM   12887 N  N   . CYS B 1 785 ? 133.634 180.021 138.803 1.00 86.80  ? 785  CYS B N   1 
ATOM   12888 C  CA  . CYS B 1 785 ? 133.730 181.135 137.864 1.00 86.80  ? 785  CYS B CA  1 
ATOM   12889 C  C   . CYS B 1 785 ? 134.985 181.022 137.007 1.00 86.80  ? 785  CYS B C   1 
ATOM   12890 O  O   . CYS B 1 785 ? 134.948 181.271 135.794 1.00 86.80  ? 785  CYS B O   1 
ATOM   12891 C  CB  . CYS B 1 785 ? 133.720 182.463 138.622 1.00 86.80  ? 785  CYS B CB  1 
ATOM   12892 S  SG  . CYS B 1 785 ? 132.087 183.030 139.149 1.00 86.80  ? 785  CYS B SG  1 
ATOM   12893 N  N   . LEU B 1 786 ? 136.104 180.639 137.625 1.00 87.72  ? 786  LEU B N   1 
ATOM   12894 C  CA  . LEU B 1 786 ? 137.357 180.487 136.892 1.00 87.72  ? 786  LEU B CA  1 
ATOM   12895 C  C   . LEU B 1 786 ? 137.230 179.432 135.801 1.00 87.72  ? 786  LEU B C   1 
ATOM   12896 O  O   . LEU B 1 786 ? 137.698 179.626 134.674 1.00 87.72  ? 786  LEU B O   1 
ATOM   12897 C  CB  . LEU B 1 786 ? 138.481 180.123 137.862 1.00 87.72  ? 786  LEU B CB  1 
ATOM   12898 C  CG  . LEU B 1 786 ? 139.869 179.890 137.265 1.00 87.72  ? 786  LEU B CG  1 
ATOM   12899 C  CD1 . LEU B 1 786 ? 140.528 181.208 136.894 1.00 87.72  ? 786  LEU B CD1 1 
ATOM   12900 C  CD2 . LEU B 1 786 ? 140.740 179.099 138.229 1.00 87.72  ? 786  LEU B CD2 1 
ATOM   12901 N  N   . MET B 1 787 ? 136.601 178.301 136.122 1.00 90.36  ? 787  MET B N   1 
ATOM   12902 C  CA  . MET B 1 787 ? 136.430 177.252 135.122 1.00 90.36  ? 787  MET B CA  1 
ATOM   12903 C  C   . MET B 1 787 ? 135.394 177.634 134.071 1.00 90.36  ? 787  MET B C   1 
ATOM   12904 O  O   . MET B 1 787 ? 135.502 177.207 132.915 1.00 90.36  ? 787  MET B O   1 
ATOM   12905 C  CB  . MET B 1 787 ? 136.047 175.936 135.797 1.00 90.36  ? 787  MET B CB  1 
ATOM   12906 C  CG  . MET B 1 787 ? 137.134 175.353 136.679 1.00 90.36  ? 787  MET B CG  1 
ATOM   12907 S  SD  . MET B 1 787 ? 138.651 175.043 135.757 1.00 90.36  ? 787  MET B SD  1 
ATOM   12908 C  CE  . MET B 1 787 ? 138.095 173.806 134.590 1.00 90.36  ? 787  MET B CE  1 
ATOM   12909 N  N   . TRP B 1 788 ? 134.385 178.422 134.447 1.00 94.24  ? 788  TRP B N   1 
ATOM   12910 C  CA  . TRP B 1 788 ? 133.327 178.771 133.504 1.00 94.24  ? 788  TRP B CA  1 
ATOM   12911 C  C   . TRP B 1 788 ? 133.807 179.786 132.472 1.00 94.24  ? 788  TRP B C   1 
ATOM   12912 O  O   . TRP B 1 788 ? 133.576 179.617 131.270 1.00 94.24  ? 788  TRP B O   1 
ATOM   12913 C  CB  . TRP B 1 788 ? 132.112 179.306 134.260 1.00 94.24  ? 788  TRP B CB  1 
ATOM   12914 C  CG  . TRP B 1 788 ? 130.942 179.592 133.375 1.00 94.24  ? 788  TRP B CG  1 
ATOM   12915 C  CD1 . TRP B 1 788 ? 130.525 180.813 132.936 1.00 94.24  ? 788  TRP B CD1 1 
ATOM   12916 C  CD2 . TRP B 1 788 ? 130.035 178.635 132.820 1.00 94.24  ? 788  TRP B CD2 1 
ATOM   12917 N  NE1 . TRP B 1 788 ? 129.414 180.677 132.142 1.00 94.24  ? 788  TRP B NE1 1 
ATOM   12918 C  CE2 . TRP B 1 788 ? 129.092 179.348 132.055 1.00 94.24  ? 788  TRP B CE2 1 
ATOM   12919 C  CE3 . TRP B 1 788 ? 129.929 177.244 132.896 1.00 94.24  ? 788  TRP B CE3 1 
ATOM   12920 C  CZ2 . TRP B 1 788 ? 128.058 178.718 131.370 1.00 94.24  ? 788  TRP B CZ2 1 
ATOM   12921 C  CZ3 . TRP B 1 788 ? 128.902 176.620 132.216 1.00 94.24  ? 788  TRP B CZ3 1 
ATOM   12922 C  CH2 . TRP B 1 788 ? 127.980 177.356 131.462 1.00 94.24  ? 788  TRP B CH2 1 
ATOM   12923 N  N   . TRP B 1 789 ? 134.478 180.849 132.918 1.00 90.75  ? 789  TRP B N   1 
ATOM   12924 C  CA  . TRP B 1 789 ? 134.879 181.922 132.013 1.00 90.75  ? 789  TRP B CA  1 
ATOM   12925 C  C   . TRP B 1 789 ? 136.325 181.812 131.545 1.00 90.75  ? 789  TRP B C   1 
ATOM   12926 O  O   . TRP B 1 789 ? 136.584 181.830 130.337 1.00 90.75  ? 789  TRP B O   1 
ATOM   12927 C  CB  . TRP B 1 789 ? 134.648 183.289 132.667 1.00 90.75  ? 789  TRP B CB  1 
ATOM   12928 C  CG  . TRP B 1 789 ? 133.204 183.674 132.739 1.00 90.75  ? 789  TRP B CG  1 
ATOM   12929 C  CD1 . TRP B 1 789 ? 132.495 184.369 131.801 1.00 90.75  ? 789  TRP B CD1 1 
ATOM   12930 C  CD2 . TRP B 1 789 ? 132.287 183.390 133.801 1.00 90.75  ? 789  TRP B CD2 1 
ATOM   12931 N  NE1 . TRP B 1 789 ? 131.196 184.534 132.214 1.00 90.75  ? 789  TRP B NE1 1 
ATOM   12932 C  CE2 . TRP B 1 789 ? 131.043 183.942 133.439 1.00 90.75  ? 789  TRP B CE2 1 
ATOM   12933 C  CE3 . TRP B 1 789 ? 132.396 182.722 135.023 1.00 90.75  ? 789  TRP B CE3 1 
ATOM   12934 C  CZ2 . TRP B 1 789 ? 129.917 183.845 134.254 1.00 90.75  ? 789  TRP B CZ2 1 
ATOM   12935 C  CZ3 . TRP B 1 789 ? 131.277 182.625 135.830 1.00 90.75  ? 789  TRP B CZ3 1 
ATOM   12936 C  CH2 . TRP B 1 789 ? 130.055 183.185 135.442 1.00 90.75  ? 789  TRP B CH2 1 
ATOM   12937 N  N   . VAL B 1 790 ? 137.278 181.710 132.473 1.00 91.39  ? 790  VAL B N   1 
ATOM   12938 C  CA  . VAL B 1 790 ? 138.687 181.742 132.092 1.00 91.39  ? 790  VAL B CA  1 
ATOM   12939 C  C   . VAL B 1 790 ? 139.045 180.536 131.230 1.00 91.39  ? 790  VAL B C   1 
ATOM   12940 O  O   . VAL B 1 790 ? 139.731 180.670 130.211 1.00 91.39  ? 790  VAL B O   1 
ATOM   12941 C  CB  . VAL B 1 790 ? 139.575 181.833 133.345 1.00 91.39  ? 790  VAL B CB  1 
ATOM   12942 C  CG1 . VAL B 1 790 ? 141.042 181.674 132.975 1.00 91.39  ? 790  VAL B CG1 1 
ATOM   12943 C  CG2 . VAL B 1 790 ? 139.343 183.158 134.057 1.00 91.39  ? 790  VAL B CG2 1 
ATOM   12944 N  N   . PHE B 1 791 ? 138.586 179.347 131.613 1.00 91.13  ? 791  PHE B N   1 
ATOM   12945 C  CA  . PHE B 1 791 ? 138.907 178.129 130.883 1.00 91.13  ? 791  PHE B CA  1 
ATOM   12946 C  C   . PHE B 1 791 ? 137.833 177.724 129.883 1.00 91.13  ? 791  PHE B C   1 
ATOM   12947 O  O   . PHE B 1 791 ? 137.981 176.689 129.223 1.00 91.13  ? 791  PHE B O   1 
ATOM   12948 C  CB  . PHE B 1 791 ? 139.174 176.983 131.864 1.00 91.13  ? 791  PHE B CB  1 
ATOM   12949 C  CG  . PHE B 1 791 ? 140.508 177.076 132.545 1.00 91.13  ? 791  PHE B CG  1 
ATOM   12950 C  CD1 . PHE B 1 791 ? 140.706 177.961 133.592 1.00 91.13  ? 791  PHE B CD1 1 
ATOM   12951 C  CD2 . PHE B 1 791 ? 141.570 176.293 132.127 1.00 91.13  ? 791  PHE B CD2 1 
ATOM   12952 C  CE1 . PHE B 1 791 ? 141.935 178.054 134.217 1.00 91.13  ? 791  PHE B CE1 1 
ATOM   12953 C  CE2 . PHE B 1 791 ? 142.801 176.383 132.748 1.00 91.13  ? 791  PHE B CE2 1 
ATOM   12954 C  CZ  . PHE B 1 791 ? 142.983 177.265 133.793 1.00 91.13  ? 791  PHE B CZ  1 
ATOM   12955 N  N   . HIS B 1 792 ? 136.764 178.513 129.751 1.00 91.71  ? 792  HIS B N   1 
ATOM   12956 C  CA  . HIS B 1 792 ? 135.768 178.347 128.689 1.00 91.71  ? 792  HIS B CA  1 
ATOM   12957 C  C   . HIS B 1 792 ? 135.132 176.957 128.710 1.00 91.71  ? 792  HIS B C   1 
ATOM   12958 O  O   . HIS B 1 792 ? 135.036 176.275 127.688 1.00 91.71  ? 792  HIS B O   1 
ATOM   12959 C  CB  . HIS B 1 792 ? 136.382 178.647 127.319 1.00 91.71  ? 792  HIS B CB  1 
ATOM   12960 C  CG  . HIS B 1 792 ? 137.085 179.967 127.249 1.00 91.71  ? 792  HIS B CG  1 
ATOM   12961 N  ND1 . HIS B 1 792 ? 138.456 180.078 127.174 1.00 91.71  ? 792  HIS B ND1 1 
ATOM   12962 C  CD2 . HIS B 1 792 ? 136.604 181.233 127.246 1.00 91.71  ? 792  HIS B CD2 1 
ATOM   12963 C  CE1 . HIS B 1 792 ? 138.791 181.355 127.124 1.00 91.71  ? 792  HIS B CE1 1 
ATOM   12964 N  NE2 . HIS B 1 792 ? 137.685 182.077 127.167 1.00 91.71  ? 792  HIS B NE2 1 
ATOM   12965 N  N   . ALA B 1 793 ? 134.698 176.535 129.893 1.00 92.31  ? 793  ALA B N   1 
ATOM   12966 C  CA  . ALA B 1 793 ? 133.919 175.305 130.038 1.00 92.31  ? 793  ALA B CA  1 
ATOM   12967 C  C   . ALA B 1 793 ? 132.427 175.632 130.080 1.00 92.31  ? 793  ALA B C   1 
ATOM   12968 O  O   . ALA B 1 793 ? 131.733 175.412 131.073 1.00 92.31  ? 793  ALA B O   1 
ATOM   12969 C  CB  . ALA B 1 793 ? 134.360 174.544 131.284 1.00 92.31  ? 793  ALA B CB  1 
ATOM   12970 N  N   . ASN B 1 794 ? 131.938 176.171 128.965 1.00 95.99  ? 794  ASN B N   1 
ATOM   12971 C  CA  . ASN B 1 794 ? 130.595 176.731 128.896 1.00 95.99  ? 794  ASN B CA  1 
ATOM   12972 C  C   . ASN B 1 794 ? 129.543 175.749 128.398 1.00 95.99  ? 794  ASN B C   1 
ATOM   12973 O  O   . ASN B 1 794 ? 128.358 176.100 128.379 1.00 95.99  ? 794  ASN B O   1 
ATOM   12974 C  CB  . ASN B 1 794 ? 130.593 177.968 127.992 1.00 95.99  ? 794  ASN B CB  1 
ATOM   12975 C  CG  . ASN B 1 794 ? 131.282 179.157 128.629 1.00 95.99  ? 794  ASN B CG  1 
ATOM   12976 O  OD1 . ASN B 1 794 ? 131.118 179.420 129.820 1.00 95.99  ? 794  ASN B OD1 1 
ATOM   12977 N  ND2 . ASN B 1 794 ? 132.064 179.882 127.837 1.00 95.99  ? 794  ASN B ND2 1 
ATOM   12978 N  N   . THR B 1 795 ? 129.928 174.545 127.999 1.00 95.04  ? 795  THR B N   1 
ATOM   12979 C  CA  . THR B 1 795 ? 129.005 173.576 127.433 1.00 95.04  ? 795  THR B CA  1 
ATOM   12980 C  C   . THR B 1 795 ? 129.172 172.229 128.115 1.00 95.04  ? 795  THR B C   1 
ATOM   12981 O  O   . THR B 1 795 ? 130.254 171.906 128.618 1.00 95.04  ? 795  THR B O   1 
ATOM   12982 C  CB  . THR B 1 795 ? 129.225 173.414 125.921 1.00 95.04  ? 795  THR B CB  1 
ATOM   12983 O  OG1 . THR B 1 795 ? 130.612 173.162 125.661 1.00 95.04  ? 795  THR B OG1 1 
ATOM   12984 C  CG2 . THR B 1 795 ? 128.792 174.669 125.179 1.00 95.04  ? 795  THR B CG2 1 
ATOM   12985 N  N   . PRO B 1 796 ? 128.109 171.420 128.160 1.00 92.93  ? 796  PRO B N   1 
ATOM   12986 C  CA  . PRO B 1 796 ? 128.253 170.057 128.695 1.00 92.93  ? 796  PRO B CA  1 
ATOM   12987 C  C   . PRO B 1 796 ? 129.246 169.209 127.922 1.00 92.93  ? 796  PRO B C   1 
ATOM   12988 O  O   . PRO B 1 796 ? 129.841 168.291 128.499 1.00 92.93  ? 796  PRO B O   1 
ATOM   12989 C  CB  . PRO B 1 796 ? 126.830 169.491 128.594 1.00 92.93  ? 796  PRO B CB  1 
ATOM   12990 C  CG  . PRO B 1 796 ? 125.945 170.688 128.608 1.00 92.93  ? 796  PRO B CG  1 
ATOM   12991 C  CD  . PRO B 1 796 ? 126.703 171.766 127.891 1.00 92.93  ? 796  PRO B CD  1 
ATOM   12992 N  N   . GLU B 1 797 ? 129.440 169.487 126.630 1.00 94.56  ? 797  GLU B N   1 
ATOM   12993 C  CA  . GLU B 1 797 ? 130.384 168.707 125.834 1.00 94.56  ? 797  GLU B CA  1 
ATOM   12994 C  C   . GLU B 1 797 ? 131.794 168.782 126.403 1.00 94.56  ? 797  GLU B C   1 
ATOM   12995 O  O   . GLU B 1 797 ? 132.582 167.844 126.236 1.00 94.56  ? 797  GLU B O   1 
ATOM   12996 C  CB  . GLU B 1 797 ? 130.372 169.187 124.381 1.00 94.56  ? 797  GLU B CB  1 
ATOM   12997 C  CG  . GLU B 1 797 ? 129.099 168.850 123.613 1.00 94.56  ? 797  GLU B CG  1 
ATOM   12998 C  CD  . GLU B 1 797 ? 127.923 169.724 124.008 1.00 94.56  ? 797  GLU B CD  1 
ATOM   12999 O  OE1 . GLU B 1 797 ? 128.001 170.954 123.810 1.00 94.56  ? 797  GLU B OE1 1 
ATOM   13000 O  OE2 . GLU B 1 797 ? 126.921 169.179 124.516 1.00 94.56  ? 797  GLU B OE2 1 
ATOM   13001 N  N   . THR B 1 798 ? 132.132 169.883 127.074 1.00 92.70  ? 798  THR B N   1 
ATOM   13002 C  CA  . THR B 1 798 ? 133.417 170.039 127.743 1.00 92.70  ? 798  THR B CA  1 
ATOM   13003 C  C   . THR B 1 798 ? 133.265 170.048 129.262 1.00 92.70  ? 798  THR B C   1 
ATOM   13004 O  O   . THR B 1 798 ? 134.097 170.618 129.973 1.00 92.70  ? 798  THR B O   1 
ATOM   13005 C  CB  . THR B 1 798 ? 134.119 171.312 127.270 1.00 92.70  ? 798  THR B CB  1 
ATOM   13006 O  OG1 . THR B 1 798 ? 135.362 171.461 127.967 1.00 92.70  ? 798  THR B OG1 1 
ATOM   13007 C  CG2 . THR B 1 798 ? 133.248 172.535 127.523 1.00 92.70  ? 798  THR B CG2 1 
ATOM   13008 N  N   . GLN B 1 799 ? 132.202 169.418 129.773 1.00 88.03  ? 799  GLN B N   1 
ATOM   13009 C  CA  . GLN B 1 799 ? 131.972 169.408 131.214 1.00 88.03  ? 799  GLN B CA  1 
ATOM   13010 C  C   . GLN B 1 799 ? 133.048 168.624 131.954 1.00 88.03  ? 799  GLN B C   1 
ATOM   13011 O  O   . GLN B 1 799 ? 133.328 168.914 133.123 1.00 88.03  ? 799  GLN B O   1 
ATOM   13012 C  CB  . GLN B 1 799 ? 130.589 168.834 131.525 1.00 88.03  ? 799  GLN B CB  1 
ATOM   13013 C  CG  . GLN B 1 799 ? 130.493 167.319 131.413 1.00 88.03  ? 799  GLN B CG  1 
ATOM   13014 C  CD  . GLN B 1 799 ? 129.133 166.791 131.822 1.00 88.03  ? 799  GLN B CD  1 
ATOM   13015 O  OE1 . GLN B 1 799 ? 128.116 167.459 131.643 1.00 88.03  ? 799  GLN B OE1 1 
ATOM   13016 N  NE2 . GLN B 1 799 ? 129.109 165.582 132.371 1.00 88.03  ? 799  GLN B NE2 1 
ATOM   13017 N  N   . THR B 1 800 ? 133.668 167.643 131.291 1.00 86.61  ? 800  THR B N   1 
ATOM   13018 C  CA  . THR B 1 800 ? 134.679 166.823 131.952 1.00 86.61  ? 800  THR B CA  1 
ATOM   13019 C  C   . THR B 1 800 ? 135.851 167.673 132.422 1.00 86.61  ? 800  THR B C   1 
ATOM   13020 O  O   . THR B 1 800 ? 136.406 167.439 133.502 1.00 86.61  ? 800  THR B O   1 
ATOM   13021 C  CB  . THR B 1 800 ? 135.157 165.719 131.009 1.00 86.61  ? 800  THR B CB  1 
ATOM   13022 O  OG1 . THR B 1 800 ? 134.037 164.930 130.590 1.00 86.61  ? 800  THR B OG1 1 
ATOM   13023 C  CG2 . THR B 1 800 ? 136.162 164.818 131.709 1.00 86.61  ? 800  THR B CG2 1 
ATOM   13024 N  N   . LEU B 1 801 ? 136.240 168.669 131.624 1.00 88.82  ? 801  LEU B N   1 
ATOM   13025 C  CA  . LEU B 1 801 ? 137.264 169.609 132.064 1.00 88.82  ? 801  LEU B CA  1 
ATOM   13026 C  C   . LEU B 1 801 ? 136.800 170.396 133.282 1.00 88.82  ? 801  LEU B C   1 
ATOM   13027 O  O   . LEU B 1 801 ? 137.578 170.627 134.215 1.00 88.82  ? 801  LEU B O   1 
ATOM   13028 C  CB  . LEU B 1 801 ? 137.632 170.555 130.921 1.00 88.82  ? 801  LEU B CB  1 
ATOM   13029 C  CG  . LEU B 1 801 ? 138.393 171.828 131.301 1.00 88.82  ? 801  LEU B CG  1 
ATOM   13030 C  CD1 . LEU B 1 801 ? 139.868 171.531 131.522 1.00 88.82  ? 801  LEU B CD1 1 
ATOM   13031 C  CD2 . LEU B 1 801 ? 138.209 172.903 130.241 1.00 88.82  ? 801  LEU B CD2 1 
ATOM   13032 N  N   . PHE B 1 802 ? 135.531 170.813 133.293 1.00 86.13  ? 802  PHE B N   1 
ATOM   13033 C  CA  . PHE B 1 802 ? 135.025 171.629 134.393 1.00 86.13  ? 802  PHE B CA  1 
ATOM   13034 C  C   . PHE B 1 802 ? 135.064 170.863 135.710 1.00 86.13  ? 802  PHE B C   1 
ATOM   13035 O  O   . PHE B 1 802 ? 135.655 171.325 136.694 1.00 86.13  ? 802  PHE B O   1 
ATOM   13036 C  CB  . PHE B 1 802 ? 133.599 172.089 134.081 1.00 86.13  ? 802  PHE B CB  1 
ATOM   13037 C  CG  . PHE B 1 802 ? 133.003 172.995 135.124 1.00 86.13  ? 802  PHE B CG  1 
ATOM   13038 C  CD1 . PHE B 1 802 ? 132.336 172.475 136.222 1.00 86.13  ? 802  PHE B CD1 1 
ATOM   13039 C  CD2 . PHE B 1 802 ? 133.088 174.370 134.992 1.00 86.13  ? 802  PHE B CD2 1 
ATOM   13040 C  CE1 . PHE B 1 802 ? 131.785 173.307 137.175 1.00 86.13  ? 802  PHE B CE1 1 
ATOM   13041 C  CE2 . PHE B 1 802 ? 132.538 175.208 135.943 1.00 86.13  ? 802  PHE B CE2 1 
ATOM   13042 C  CZ  . PHE B 1 802 ? 131.885 174.675 137.035 1.00 86.13  ? 802  PHE B CZ  1 
ATOM   13043 N  N   . GLN B 1 803 ? 134.467 169.669 135.733 1.00 85.28  ? 803  GLN B N   1 
ATOM   13044 C  CA  . GLN B 1 803 ? 134.333 168.925 136.982 1.00 85.28  ? 803  GLN B CA  1 
ATOM   13045 C  C   . GLN B 1 803 ? 135.696 168.596 137.574 1.00 85.28  ? 803  GLN B C   1 
ATOM   13046 O  O   . GLN B 1 803 ? 135.960 168.876 138.750 1.00 85.28  ? 803  GLN B O   1 
ATOM   13047 C  CB  . GLN B 1 803 ? 133.522 167.652 136.744 1.00 85.28  ? 803  GLN B CB  1 
ATOM   13048 C  CG  . GLN B 1 803 ? 132.188 167.897 136.061 1.00 85.28  ? 803  GLN B CG  1 
ATOM   13049 C  CD  . GLN B 1 803 ? 131.454 166.613 135.739 1.00 85.28  ? 803  GLN B CD  1 
ATOM   13050 O  OE1 . GLN B 1 803 ? 132.048 165.655 135.246 1.00 85.28  ? 803  GLN B OE1 1 
ATOM   13051 N  NE2 . GLN B 1 803 ? 130.156 166.586 136.016 1.00 85.28  ? 803  GLN B NE2 1 
ATOM   13052 N  N   . SER B 1 804 ? 136.587 168.024 136.761 1.00 81.59  ? 804  SER B N   1 
ATOM   13053 C  CA  . SER B 1 804 ? 137.940 167.749 137.230 1.00 81.59  ? 804  SER B CA  1 
ATOM   13054 C  C   . SER B 1 804 ? 138.616 169.024 137.713 1.00 81.59  ? 804  SER B C   1 
ATOM   13055 O  O   . SER B 1 804 ? 139.380 168.999 138.686 1.00 81.59  ? 804  SER B O   1 
ATOM   13056 C  CB  . SER B 1 804 ? 138.757 167.093 136.118 1.00 81.59  ? 804  SER B CB  1 
ATOM   13057 O  OG  . SER B 1 804 ? 140.075 166.814 136.555 1.00 81.59  ? 804  SER B OG  1 
ATOM   13058 N  N   . GLY B 1 805 ? 138.319 170.154 137.066 1.00 82.72  ? 805  GLY B N   1 
ATOM   13059 C  CA  . GLY B 1 805 ? 138.894 171.414 137.503 1.00 82.72  ? 805  GLY B CA  1 
ATOM   13060 C  C   . GLY B 1 805 ? 138.537 171.740 138.939 1.00 82.72  ? 805  GLY B C   1 
ATOM   13061 O  O   . GLY B 1 805 ? 139.355 172.286 139.684 1.00 82.72  ? 805  GLY B O   1 
ATOM   13062 N  N   . TRP B 1 806 ? 137.311 171.410 139.347 1.00 77.78  ? 806  TRP B N   1 
ATOM   13063 C  CA  . TRP B 1 806 ? 136.944 171.574 140.748 1.00 77.78  ? 806  TRP B CA  1 
ATOM   13064 C  C   . TRP B 1 806 ? 137.543 170.472 141.611 1.00 77.78  ? 806  TRP B C   1 
ATOM   13065 O  O   . TRP B 1 806 ? 137.907 170.722 142.767 1.00 77.78  ? 806  TRP B O   1 
ATOM   13066 C  CB  . TRP B 1 806 ? 135.423 171.597 140.893 1.00 77.78  ? 806  TRP B CB  1 
ATOM   13067 C  CG  . TRP B 1 806 ? 134.955 171.944 142.271 1.00 77.78  ? 806  TRP B CG  1 
ATOM   13068 C  CD1 . TRP B 1 806 ? 135.620 172.690 143.199 1.00 77.78  ? 806  TRP B CD1 1 
ATOM   13069 C  CD2 . TRP B 1 806 ? 133.720 171.554 142.880 1.00 77.78  ? 806  TRP B CD2 1 
ATOM   13070 N  NE1 . TRP B 1 806 ? 134.874 172.792 144.347 1.00 77.78  ? 806  TRP B NE1 1 
ATOM   13071 C  CE2 . TRP B 1 806 ? 133.702 172.103 144.177 1.00 77.78  ? 806  TRP B CE2 1 
ATOM   13072 C  CE3 . TRP B 1 806 ? 132.624 170.798 142.453 1.00 77.78  ? 806  TRP B CE3 1 
ATOM   13073 C  CZ2 . TRP B 1 806 ? 132.635 171.918 145.051 1.00 77.78  ? 806  TRP B CZ2 1 
ATOM   13074 C  CZ3 . TRP B 1 806 ? 131.566 170.614 143.322 1.00 77.78  ? 806  TRP B CZ3 1 
ATOM   13075 C  CH2 . TRP B 1 806 ? 131.579 171.172 144.606 1.00 77.78  ? 806  TRP B CH2 1 
ATOM   13076 N  N   . PHE B 1 807 ? 137.679 169.262 141.057 1.00 70.72  ? 807  PHE B N   1 
ATOM   13077 C  CA  . PHE B 1 807 ? 138.052 168.103 141.863 1.00 70.72  ? 807  PHE B CA  1 
ATOM   13078 C  C   . PHE B 1 807 ? 139.375 168.331 142.582 1.00 70.72  ? 807  PHE B C   1 
ATOM   13079 O  O   . PHE B 1 807 ? 139.468 168.161 143.803 1.00 70.72  ? 807  PHE B O   1 
ATOM   13080 C  CB  . PHE B 1 807 ? 138.118 166.857 140.976 1.00 70.72  ? 807  PHE B CB  1 
ATOM   13081 C  CG  . PHE B 1 807 ? 138.687 165.647 141.662 1.00 70.72  ? 807  PHE B CG  1 
ATOM   13082 C  CD1 . PHE B 1 807 ? 137.870 164.809 142.401 1.00 70.72  ? 807  PHE B CD1 1 
ATOM   13083 C  CD2 . PHE B 1 807 ? 140.031 165.334 141.549 1.00 70.72  ? 807  PHE B CD2 1 
ATOM   13084 C  CE1 . PHE B 1 807 ? 138.387 163.693 143.028 1.00 70.72  ? 807  PHE B CE1 1 
ATOM   13085 C  CE2 . PHE B 1 807 ? 140.552 164.220 142.175 1.00 70.72  ? 807  PHE B CE2 1 
ATOM   13086 C  CZ  . PHE B 1 807 ? 139.729 163.398 142.914 1.00 70.72  ? 807  PHE B CZ  1 
ATOM   13087 N  N   . VAL B 1 808 ? 140.404 168.747 141.842 1.00 73.14  ? 808  VAL B N   1 
ATOM   13088 C  CA  . VAL B 1 808 ? 141.704 168.996 142.457 1.00 73.14  ? 808  VAL B CA  1 
ATOM   13089 C  C   . VAL B 1 808 ? 141.601 170.108 143.490 1.00 73.14  ? 808  VAL B C   1 
ATOM   13090 O  O   . VAL B 1 808 ? 142.264 170.061 144.533 1.00 73.14  ? 808  VAL B O   1 
ATOM   13091 C  CB  . VAL B 1 808 ? 142.754 169.316 141.377 1.00 73.14  ? 808  VAL B CB  1 
ATOM   13092 C  CG1 . VAL B 1 808 ? 144.145 169.363 141.987 1.00 73.14  ? 808  VAL B CG1 1 
ATOM   13093 C  CG2 . VAL B 1 808 ? 142.689 168.289 140.261 1.00 73.14  ? 808  VAL B CG2 1 
ATOM   13094 N  N   . VAL B 1 809 ? 140.775 171.123 143.227 1.00 73.91  ? 809  VAL B N   1 
ATOM   13095 C  CA  . VAL B 1 809 ? 140.540 172.149 144.237 1.00 73.91  ? 809  VAL B CA  1 
ATOM   13096 C  C   . VAL B 1 809 ? 139.758 171.571 145.408 1.00 73.91  ? 809  VAL B C   1 
ATOM   13097 O  O   . VAL B 1 809 ? 140.015 171.907 146.570 1.00 73.91  ? 809  VAL B O   1 
ATOM   13098 C  CB  . VAL B 1 809 ? 139.822 173.360 143.615 1.00 73.91  ? 809  VAL B CB  1 
ATOM   13099 C  CG1 . VAL B 1 809 ? 139.439 174.364 144.690 1.00 73.91  ? 809  VAL B CG1 1 
ATOM   13100 C  CG2 . VAL B 1 809 ? 140.710 174.017 142.581 1.00 73.91  ? 809  VAL B CG2 1 
ATOM   13101 N  N   . GLY B 1 810 ? 138.800 170.686 145.125 1.00 70.76  ? 810  GLY B N   1 
ATOM   13102 C  CA  . GLY B 1 810 ? 137.972 170.149 146.193 1.00 70.76  ? 810  GLY B CA  1 
ATOM   13103 C  C   . GLY B 1 810 ? 138.755 169.299 147.174 1.00 70.76  ? 810  GLY B C   1 
ATOM   13104 O  O   . GLY B 1 810 ? 138.603 169.431 148.390 1.00 70.76  ? 810  GLY B O   1 
ATOM   13105 N  N   . LEU B 1 811 ? 139.603 168.409 146.658 1.00 66.74  ? 811  LEU B N   1 
ATOM   13106 C  CA  . LEU B 1 811 ? 140.308 167.472 147.526 1.00 66.74  ? 811  LEU B CA  1 
ATOM   13107 C  C   . LEU B 1 811 ? 141.449 168.136 148.287 1.00 66.74  ? 811  LEU B C   1 
ATOM   13108 O  O   . LEU B 1 811 ? 141.602 167.912 149.493 1.00 66.74  ? 811  LEU B O   1 
ATOM   13109 C  CB  . LEU B 1 811 ? 140.834 166.297 146.706 1.00 66.74  ? 811  LEU B CB  1 
ATOM   13110 C  CG  . LEU B 1 811 ? 141.710 165.298 147.462 1.00 66.74  ? 811  LEU B CG  1 
ATOM   13111 C  CD1 . LEU B 1 811 ? 140.979 164.745 148.676 1.00 66.74  ? 811  LEU B CD1 1 
ATOM   13112 C  CD2 . LEU B 1 811 ? 142.144 164.179 146.539 1.00 66.74  ? 811  LEU B CD2 1 
ATOM   13113 N  N   . LEU B 1 812 ? 142.261 168.949 147.607 1.00 68.62  ? 812  LEU B N   1 
ATOM   13114 C  CA  . LEU B 1 812 ? 143.447 169.505 148.253 1.00 68.62  ? 812  LEU B CA  1 
ATOM   13115 C  C   . LEU B 1 812 ? 143.081 170.538 149.311 1.00 68.62  ? 812  LEU B C   1 
ATOM   13116 O  O   . LEU B 1 812 ? 143.603 170.493 150.431 1.00 68.62  ? 812  LEU B O   1 
ATOM   13117 C  CB  . LEU B 1 812 ? 144.387 170.110 147.210 1.00 68.62  ? 812  LEU B CB  1 
ATOM   13118 C  CG  . LEU B 1 812 ? 145.358 169.151 146.513 1.00 68.62  ? 812  LEU B CG  1 
ATOM   13119 C  CD1 . LEU B 1 812 ? 144.655 168.218 145.537 1.00 68.62  ? 812  LEU B CD1 1 
ATOM   13120 C  CD2 . LEU B 1 812 ? 146.459 169.934 145.816 1.00 68.62  ? 812  LEU B CD2 1 
ATOM   13121 N  N   . SER B 1 813 ? 142.188 171.475 148.981 1.00 66.30  ? 813  SER B N   1 
ATOM   13122 C  CA  . SER B 1 813 ? 141.788 172.483 149.958 1.00 66.30  ? 813  SER B CA  1 
ATOM   13123 C  C   . SER B 1 813 ? 141.201 171.826 151.200 1.00 66.30  ? 813  SER B C   1 
ATOM   13124 O  O   . SER B 1 813 ? 141.603 172.132 152.329 1.00 66.30  ? 813  SER B O   1 
ATOM   13125 C  CB  . SER B 1 813 ? 140.784 173.452 149.334 1.00 66.30  ? 813  SER B CB  1 
ATOM   13126 O  OG  . SER B 1 813 ? 139.639 172.762 148.865 1.00 66.30  ? 813  SER B OG  1 
ATOM   13127 N  N   . GLN B 1 814 ? 140.271 170.888 151.001 1.00 65.94  ? 814  GLN B N   1 
ATOM   13128 C  CA  . GLN B 1 814 ? 139.718 170.122 152.113 1.00 65.94  ? 814  GLN B CA  1 
ATOM   13129 C  C   . GLN B 1 814 ? 140.819 169.459 152.927 1.00 65.94  ? 814  GLN B C   1 
ATOM   13130 O  O   . GLN B 1 814 ? 140.718 169.349 154.154 1.00 65.94  ? 814  GLN B O   1 
ATOM   13131 C  CB  . GLN B 1 814 ? 138.742 169.073 151.580 1.00 65.94  ? 814  GLN B CB  1 
ATOM   13132 C  CG  . GLN B 1 814 ? 137.833 168.468 152.627 1.00 65.94  ? 814  GLN B CG  1 
ATOM   13133 C  CD  . GLN B 1 814 ? 136.888 167.437 152.043 1.00 65.94  ? 814  GLN B CD  1 
ATOM   13134 O  OE1 . GLN B 1 814 ? 137.059 166.996 150.907 1.00 65.94  ? 814  GLN B OE1 1 
ATOM   13135 N  NE2 . GLN B 1 814 ? 135.885 167.046 152.820 1.00 65.94  ? 814  GLN B NE2 1 
ATOM   13136 N  N   . THR B 1 815 ? 141.882 169.009 152.259 1.00 64.25  ? 815  THR B N   1 
ATOM   13137 C  CA  . THR B 1 815 ? 143.007 168.425 152.975 1.00 64.25  ? 815  THR B CA  1 
ATOM   13138 C  C   . THR B 1 815 ? 143.877 169.500 153.620 1.00 64.25  ? 815  THR B C   1 
ATOM   13139 O  O   . THR B 1 815 ? 144.381 169.308 154.732 1.00 64.25  ? 815  THR B O   1 
ATOM   13140 C  CB  . THR B 1 815 ? 143.837 167.560 152.027 1.00 64.25  ? 815  THR B CB  1 
ATOM   13141 O  OG1 . THR B 1 815 ? 142.980 166.626 151.360 1.00 64.25  ? 815  THR B OG1 1 
ATOM   13142 C  CG2 . THR B 1 815 ? 144.889 166.789 152.798 1.00 64.25  ? 815  THR B CG2 1 
ATOM   13143 N  N   . LEU B 1 816 ? 144.058 170.638 152.944 1.00 66.88  ? 816  LEU B N   1 
ATOM   13144 C  CA  . LEU B 1 816 ? 144.961 171.660 153.464 1.00 66.88  ? 816  LEU B CA  1 
ATOM   13145 C  C   . LEU B 1 816 ? 144.339 172.418 154.630 1.00 66.88  ? 816  LEU B C   1 
ATOM   13146 O  O   . LEU B 1 816 ? 145.016 172.695 155.628 1.00 66.88  ? 816  LEU B O   1 
ATOM   13147 C  CB  . LEU B 1 816 ? 145.362 172.626 152.350 1.00 66.88  ? 816  LEU B CB  1 
ATOM   13148 C  CG  . LEU B 1 816 ? 146.672 172.294 151.635 1.00 66.88  ? 816  LEU B CG  1 
ATOM   13149 C  CD1 . LEU B 1 816 ? 146.896 173.226 150.458 1.00 66.88  ? 816  LEU B CD1 1 
ATOM   13150 C  CD2 . LEU B 1 816 ? 147.841 172.362 152.605 1.00 66.88  ? 816  LEU B CD2 1 
ATOM   13151 N  N   . ILE B 1 817 ? 143.048 172.742 154.528 1.00 66.84  ? 817  ILE B N   1 
ATOM   13152 C  CA  . ILE B 1 817 ? 142.367 173.564 155.519 1.00 66.84  ? 817  ILE B CA  1 
ATOM   13153 C  C   . ILE B 1 817 ? 142.531 173.038 156.937 1.00 66.84  ? 817  ILE B C   1 
ATOM   13154 O  O   . ILE B 1 817 ? 142.464 173.821 157.890 1.00 66.84  ? 817  ILE B O   1 
ATOM   13155 C  CB  . ILE B 1 817 ? 140.871 173.695 155.152 1.00 66.84  ? 817  ILE B CB  1 
ATOM   13156 C  CG1 . ILE B 1 817 ? 140.201 174.777 155.997 1.00 66.84  ? 817  ILE B CG1 1 
ATOM   13157 C  CG2 . ILE B 1 817 ? 140.152 172.365 155.320 1.00 66.84  ? 817  ILE B CG2 1 
ATOM   13158 C  CD1 . ILE B 1 817 ? 140.752 176.155 155.760 1.00 66.84  ? 817  ILE B CD1 1 
ATOM   13159 N  N   . VAL B 1 818 ? 142.782 171.735 157.096 1.00 64.50  ? 818  VAL B N   1 
ATOM   13160 C  CA  . VAL B 1 818 ? 142.984 171.167 158.425 1.00 64.50  ? 818  VAL B CA  1 
ATOM   13161 C  C   . VAL B 1 818 ? 144.104 171.896 159.153 1.00 64.50  ? 818  VAL B C   1 
ATOM   13162 O  O   . VAL B 1 818 ? 143.927 172.359 160.288 1.00 64.50  ? 818  VAL B O   1 
ATOM   13163 C  CB  . VAL B 1 818 ? 143.268 169.658 158.315 1.00 64.50  ? 818  VAL B CB  1 
ATOM   13164 C  CG1 . VAL B 1 818 ? 143.919 169.143 159.588 1.00 64.50  ? 818  VAL B CG1 1 
ATOM   13165 C  CG2 . VAL B 1 818 ? 141.984 168.905 158.022 1.00 64.50  ? 818  VAL B CG2 1 
ATOM   13166 N  N   . HIS B 1 819 ? 145.250 172.068 158.490 1.00 65.35  ? 819  HIS B N   1 
ATOM   13167 C  CA  . HIS B 1 819 ? 146.381 172.730 159.128 1.00 65.35  ? 819  HIS B CA  1 
ATOM   13168 C  C   . HIS B 1 819 ? 146.080 174.175 159.493 1.00 65.35  ? 819  HIS B C   1 
ATOM   13169 O  O   . HIS B 1 819 ? 146.822 174.763 160.287 1.00 65.35  ? 819  HIS B O   1 
ATOM   13170 C  CB  . HIS B 1 819 ? 147.611 172.668 158.223 1.00 65.35  ? 819  HIS B CB  1 
ATOM   13171 C  CG  . HIS B 1 819 ? 148.110 171.279 157.979 1.00 65.35  ? 819  HIS B CG  1 
ATOM   13172 N  ND1 . HIS B 1 819 ? 149.107 170.704 158.737 1.00 65.35  ? 819  HIS B ND1 1 
ATOM   13173 C  CD2 . HIS B 1 819 ? 147.749 170.348 157.064 1.00 65.35  ? 819  HIS B CD2 1 
ATOM   13174 C  CE1 . HIS B 1 819 ? 149.340 169.479 158.299 1.00 65.35  ? 819  HIS B CE1 1 
ATOM   13175 N  NE2 . HIS B 1 819 ? 148.529 169.239 157.284 1.00 65.35  ? 819  HIS B NE2 1 
ATOM   13176 N  N   . MET B 1 820 ? 145.020 174.757 158.937 1.00 70.89  ? 820  MET B N   1 
ATOM   13177 C  CA  . MET B 1 820 ? 144.605 176.098 159.317 1.00 70.89  ? 820  MET B CA  1 
ATOM   13178 C  C   . MET B 1 820 ? 143.539 176.092 160.405 1.00 70.89  ? 820  MET B C   1 
ATOM   13179 O  O   . MET B 1 820 ? 143.458 177.042 161.190 1.00 70.89  ? 820  MET B O   1 
ATOM   13180 C  CB  . MET B 1 820 ? 144.090 176.856 158.092 1.00 70.89  ? 820  MET B CB  1 
ATOM   13181 C  CG  . MET B 1 820 ? 145.186 177.416 157.204 1.00 70.89  ? 820  MET B CG  1 
ATOM   13182 S  SD  . MET B 1 820 ? 146.063 178.787 157.978 1.00 70.89  ? 820  MET B SD  1 
ATOM   13183 C  CE  . MET B 1 820 ? 147.733 178.480 157.412 1.00 70.89  ? 820  MET B CE  1 
ATOM   13184 N  N   . ILE B 1 821 ? 142.723 175.043 160.481 1.00 65.25  ? 821  ILE B N   1 
ATOM   13185 C  CA  . ILE B 1 821 ? 141.569 175.037 161.373 1.00 65.25  ? 821  ILE B CA  1 
ATOM   13186 C  C   . ILE B 1 821 ? 141.743 174.040 162.520 1.00 65.25  ? 821  ILE B C   1 
ATOM   13187 O  O   . ILE B 1 821 ? 140.767 173.679 163.175 1.00 65.25  ? 821  ILE B O   1 
ATOM   13188 C  CB  . ILE B 1 821 ? 140.263 174.779 160.607 1.00 65.25  ? 821  ILE B CB  1 
ATOM   13189 C  CG1 . ILE B 1 821 ? 140.241 173.360 160.036 1.00 65.25  ? 821  ILE B CG1 1 
ATOM   13190 C  CG2 . ILE B 1 821 ? 140.082 175.808 159.504 1.00 65.25  ? 821  ILE B CG2 1 
ATOM   13191 C  CD1 . ILE B 1 821 ? 138.967 173.021 159.294 1.00 65.25  ? 821  ILE B CD1 1 
ATOM   13192 N  N   . ARG B 1 822 ? 142.969 173.592 162.777 1.00 65.14  ? 822  ARG B N   1 
ATOM   13193 C  CA  . ARG B 1 822 ? 143.213 172.697 163.898 1.00 65.14  ? 822  ARG B CA  1 
ATOM   13194 C  C   . ARG B 1 822 ? 143.670 173.426 165.152 1.00 65.14  ? 822  ARG B C   1 
ATOM   13195 O  O   . ARG B 1 822 ? 143.551 172.871 166.250 1.00 65.14  ? 822  ARG B O   1 
ATOM   13196 C  CB  . ARG B 1 822 ? 144.259 171.644 163.521 1.00 65.14  ? 822  ARG B CB  1 
ATOM   13197 C  CG  . ARG B 1 822 ? 145.613 172.218 163.149 1.00 65.14  ? 822  ARG B CG  1 
ATOM   13198 C  CD  . ARG B 1 822 ? 146.619 171.113 162.884 1.00 65.14  ? 822  ARG B CD  1 
ATOM   13199 N  NE  . ARG B 1 822 ? 147.149 170.558 164.123 1.00 65.14  ? 822  ARG B NE  1 
ATOM   13200 C  CZ  . ARG B 1 822 ? 148.164 171.076 164.800 1.00 65.14  ? 822  ARG B CZ  1 
ATOM   13201 N  NH1 . ARG B 1 822 ? 148.792 172.163 164.382 1.00 65.14  ? 822  ARG B NH1 1 
ATOM   13202 N  NH2 . ARG B 1 822 ? 148.562 170.487 165.925 1.00 65.14  ? 822  ARG B NH2 1 
ATOM   13203 N  N   . THR B 1 823 ? 144.187 174.646 165.021 1.00 75.50  ? 823  THR B N   1 
ATOM   13204 C  CA  . THR B 1 823 ? 144.697 175.398 166.158 1.00 75.50  ? 823  THR B CA  1 
ATOM   13205 C  C   . THR B 1 823 ? 144.200 176.834 166.088 1.00 75.50  ? 823  THR B C   1 
ATOM   13206 O  O   . THR B 1 823 ? 143.997 177.386 165.004 1.00 75.50  ? 823  THR B O   1 
ATOM   13207 C  CB  . THR B 1 823 ? 146.233 175.398 166.204 1.00 75.50  ? 823  THR B CB  1 
ATOM   13208 O  OG1 . THR B 1 823 ? 146.749 176.010 165.015 1.00 75.50  ? 823  THR B OG1 1 
ATOM   13209 C  CG2 . THR B 1 823 ? 146.772 173.980 166.312 1.00 75.50  ? 823  THR B CG2 1 
ATOM   13210 N  N   . ARG B 1 824 ? 144.004 177.433 167.263 1.00 80.27  ? 824  ARG B N   1 
ATOM   13211 C  CA  . ARG B 1 824 ? 143.701 178.856 167.347 1.00 80.27  ? 824  ARG B CA  1 
ATOM   13212 C  C   . ARG B 1 824 ? 144.935 179.717 167.116 1.00 80.27  ? 824  ARG B C   1 
ATOM   13213 O  O   . ARG B 1 824 ? 144.802 180.901 166.788 1.00 80.27  ? 824  ARG B O   1 
ATOM   13214 C  CB  . ARG B 1 824 ? 143.085 179.179 168.711 1.00 80.27  ? 824  ARG B CB  1 
ATOM   13215 C  CG  . ARG B 1 824 ? 142.223 180.432 168.745 1.00 80.27  ? 824  ARG B CG  1 
ATOM   13216 C  CD  . ARG B 1 824 ? 142.992 181.643 169.258 1.00 80.27  ? 824  ARG B CD  1 
ATOM   13217 N  NE  . ARG B 1 824 ? 143.567 181.415 170.579 1.00 80.27  ? 824  ARG B NE  1 
ATOM   13218 C  CZ  . ARG B 1 824 ? 144.509 182.172 171.127 1.00 80.27  ? 824  ARG B CZ  1 
ATOM   13219 N  NH1 . ARG B 1 824 ? 145.007 183.222 170.495 1.00 80.27  ? 824  ARG B NH1 1 
ATOM   13220 N  NH2 . ARG B 1 824 ? 144.960 181.869 172.341 1.00 80.27  ? 824  ARG B NH2 1 
ATOM   13221 N  N   . ARG B 1 825 ? 146.123 179.143 167.267 1.00 82.88  ? 825  ARG B N   1 
ATOM   13222 C  CA  . ARG B 1 825 ? 147.383 179.851 167.112 1.00 82.88  ? 825  ARG B CA  1 
ATOM   13223 C  C   . ARG B 1 825 ? 147.802 179.798 165.642 1.00 82.88  ? 825  ARG B C   1 
ATOM   13224 O  O   . ARG B 1 825 ? 147.317 178.966 164.871 1.00 82.88  ? 825  ARG B O   1 
ATOM   13225 C  CB  . ARG B 1 825 ? 148.410 179.237 168.062 1.00 82.88  ? 825  ARG B CB  1 
ATOM   13226 C  CG  . ARG B 1 825 ? 148.001 179.374 169.524 1.00 82.88  ? 825  ARG B CG  1 
ATOM   13227 C  CD  . ARG B 1 825 ? 148.930 178.641 170.481 1.00 82.88  ? 825  ARG B CD  1 
ATOM   13228 N  NE  . ARG B 1 825 ? 150.251 179.244 170.600 1.00 82.88  ? 825  ARG B NE  1 
ATOM   13229 C  CZ  . ARG B 1 825 ? 151.259 178.690 171.259 1.00 82.88  ? 825  ARG B CZ  1 
ATOM   13230 N  NH1 . ARG B 1 825 ? 151.129 177.520 171.862 1.00 82.88  ? 825  ARG B NH1 1 
ATOM   13231 N  NH2 . ARG B 1 825 ? 152.424 179.327 171.322 1.00 82.88  ? 825  ARG B NH2 1 
ATOM   13232 N  N   . VAL B 1 826 ? 148.705 180.684 165.231 1.00 88.47  ? 826  VAL B N   1 
ATOM   13233 C  CA  . VAL B 1 826 ? 149.086 180.777 163.822 1.00 88.47  ? 826  VAL B CA  1 
ATOM   13234 C  C   . VAL B 1 826 ? 149.904 179.550 163.430 1.00 88.47  ? 826  VAL B C   1 
ATOM   13235 O  O   . VAL B 1 826 ? 150.882 179.203 164.109 1.00 88.47  ? 826  VAL B O   1 
ATOM   13236 C  CB  . VAL B 1 826 ? 149.832 182.090 163.525 1.00 88.47  ? 826  VAL B CB  1 
ATOM   13237 C  CG1 . VAL B 1 826 ? 148.888 183.273 163.683 1.00 88.47  ? 826  VAL B CG1 1 
ATOM   13238 C  CG2 . VAL B 1 826 ? 151.020 182.262 164.447 1.00 88.47  ? 826  VAL B CG2 1 
ATOM   13239 N  N   . PRO B 1 827 ? 149.527 178.860 162.357 1.00 86.43  ? 827  PRO B N   1 
ATOM   13240 C  CA  . PRO B 1 827 ? 150.160 177.577 162.035 1.00 86.43  ? 827  PRO B CA  1 
ATOM   13241 C  C   . PRO B 1 827 ? 151.592 177.737 161.547 1.00 86.43  ? 827  PRO B C   1 
ATOM   13242 O  O   . PRO B 1 827 ? 152.012 178.798 161.081 1.00 86.43  ? 827  PRO B O   1 
ATOM   13243 C  CB  . PRO B 1 827 ? 149.265 177.008 160.926 1.00 86.43  ? 827  PRO B CB  1 
ATOM   13244 C  CG  . PRO B 1 827 ? 147.985 177.791 161.014 1.00 86.43  ? 827  PRO B CG  1 
ATOM   13245 C  CD  . PRO B 1 827 ? 148.398 179.152 161.462 1.00 86.43  ? 827  PRO B CD  1 
ATOM   13246 N  N   . PHE B 1 828 ? 152.351 176.649 161.707 1.00 89.06  ? 828  PHE B N   1 
ATOM   13247 C  CA  . PHE B 1 828 ? 153.665 176.450 161.102 1.00 89.06  ? 828  PHE B CA  1 
ATOM   13248 C  C   . PHE B 1 828 ? 154.755 177.308 161.734 1.00 89.06  ? 828  PHE B C   1 
ATOM   13249 O  O   . PHE B 1 828 ? 155.937 177.139 161.418 1.00 89.06  ? 828  PHE B O   1 
ATOM   13250 C  CB  . PHE B 1 828 ? 153.606 176.711 159.593 1.00 89.06  ? 828  PHE B CB  1 
ATOM   13251 C  CG  . PHE B 1 828 ? 152.808 175.691 158.832 1.00 89.06  ? 828  PHE B CG  1 
ATOM   13252 C  CD1 . PHE B 1 828 ? 153.359 174.463 158.510 1.00 89.06  ? 828  PHE B CD1 1 
ATOM   13253 C  CD2 . PHE B 1 828 ? 151.508 175.961 158.439 1.00 89.06  ? 828  PHE B CD2 1 
ATOM   13254 C  CE1 . PHE B 1 828 ? 152.629 173.522 157.809 1.00 89.06  ? 828  PHE B CE1 1 
ATOM   13255 C  CE2 . PHE B 1 828 ? 150.772 175.023 157.738 1.00 89.06  ? 828  PHE B CE2 1 
ATOM   13256 C  CZ  . PHE B 1 828 ? 151.334 173.803 157.423 1.00 89.06  ? 828  PHE B CZ  1 
ATOM   13257 N  N   . ILE B 1 829 ? 154.382 178.224 162.629 1.00 92.84  ? 829  ILE B N   1 
ATOM   13258 C  CA  . ILE B 1 829 ? 155.342 179.013 163.387 1.00 92.84  ? 829  ILE B CA  1 
ATOM   13259 C  C   . ILE B 1 829 ? 155.050 178.982 164.881 1.00 92.84  ? 829  ILE B C   1 
ATOM   13260 O  O   . ILE B 1 829 ? 155.961 178.776 165.690 1.00 92.84  ? 829  ILE B O   1 
ATOM   13261 C  CB  . ILE B 1 829 ? 155.413 180.470 162.874 1.00 92.84  ? 829  ILE B CB  1 
ATOM   13262 C  CG1 . ILE B 1 829 ? 154.016 181.070 162.714 1.00 92.84  ? 829  ILE B CG1 1 
ATOM   13263 C  CG2 . ILE B 1 829 ? 156.181 180.538 161.561 1.00 92.84  ? 829  ILE B CG2 1 
ATOM   13264 C  CD1 . ILE B 1 829 ? 154.030 182.543 162.370 1.00 92.84  ? 829  ILE B CD1 1 
ATOM   13265 N  N   . GLN B 1 830 ? 153.791 179.180 165.272 1.00 89.22  ? 830  GLN B N   1 
ATOM   13266 C  CA  . GLN B 1 830 ? 153.413 179.154 166.677 1.00 89.22  ? 830  GLN B CA  1 
ATOM   13267 C  C   . GLN B 1 830 ? 152.829 177.818 167.113 1.00 89.22  ? 830  GLN B C   1 
ATOM   13268 O  O   . GLN B 1 830 ? 152.845 177.515 168.311 1.00 89.22  ? 830  GLN B O   1 
ATOM   13269 C  CB  . GLN B 1 830 ? 152.404 180.270 166.974 1.00 89.22  ? 830  GLN B CB  1 
ATOM   13270 C  CG  . GLN B 1 830 ? 152.374 180.718 168.422 1.00 89.22  ? 830  GLN B CG  1 
ATOM   13271 C  CD  . GLN B 1 830 ? 151.516 181.949 168.635 1.00 89.22  ? 830  GLN B CD  1 
ATOM   13272 O  OE1 . GLN B 1 830 ? 150.918 182.474 167.696 1.00 89.22  ? 830  GLN B OE1 1 
ATOM   13273 N  NE2 . GLN B 1 830 ? 151.451 182.418 169.876 1.00 89.22  ? 830  GLN B NE2 1 
ATOM   13274 N  N   . SER B 1 831 ? 152.320 177.021 166.177 1.00 86.41  ? 831  SER B N   1 
ATOM   13275 C  CA  . SER B 1 831 ? 151.821 175.688 166.476 1.00 86.41  ? 831  SER B CA  1 
ATOM   13276 C  C   . SER B 1 831 ? 151.955 174.833 165.227 1.00 86.41  ? 831  SER B C   1 
ATOM   13277 O  O   . SER B 1 831 ? 151.674 175.296 164.118 1.00 86.41  ? 831  SER B O   1 
ATOM   13278 C  CB  . SER B 1 831 ? 150.362 175.722 166.948 1.00 86.41  ? 831  SER B CB  1 
ATOM   13279 O  OG  . SER B 1 831 ? 149.496 176.139 165.907 1.00 86.41  ? 831  SER B OG  1 
ATOM   13280 N  N   . CYS B 1 832 ? 152.383 173.588 165.412 1.00 79.07  ? 832  CYS B N   1 
ATOM   13281 C  CA  . CYS B 1 832 ? 152.632 172.680 164.303 1.00 79.07  ? 832  CYS B CA  1 
ATOM   13282 C  C   . CYS B 1 832 ? 151.931 171.354 164.551 1.00 79.07  ? 832  CYS B C   1 
ATOM   13283 O  O   . CYS B 1 832 ? 151.729 170.942 165.697 1.00 79.07  ? 832  CYS B O   1 
ATOM   13284 C  CB  . CYS B 1 832 ? 154.134 172.443 164.098 1.00 79.07  ? 832  CYS B CB  1 
ATOM   13285 S  SG  . CYS B 1 832 ? 155.013 173.834 163.351 1.00 79.07  ? 832  CYS B SG  1 
ATOM   13286 N  N   . ALA B 1 833 ? 151.562 170.690 163.461 1.00 68.35  ? 833  ALA B N   1 
ATOM   13287 C  CA  . ALA B 1 833 ? 150.922 169.385 163.537 1.00 68.35  ? 833  ALA B CA  1 
ATOM   13288 C  C   . ALA B 1 833 ? 151.988 168.315 163.772 1.00 68.35  ? 833  ALA B C   1 
ATOM   13289 O  O   . ALA B 1 833 ? 153.165 168.603 164.002 1.00 68.35  ? 833  ALA B O   1 
ATOM   13290 C  CB  . ALA B 1 833 ? 150.111 169.120 162.273 1.00 68.35  ? 833  ALA B CB  1 
ATOM   13291 N  N   . SER B 1 834 ? 151.576 167.053 163.713 1.00 67.75  ? 834  SER B N   1 
ATOM   13292 C  CA  . SER B 1 834 ? 152.471 165.924 163.912 1.00 67.75  ? 834  SER B CA  1 
ATOM   13293 C  C   . SER B 1 834 ? 152.954 165.411 162.564 1.00 67.75  ? 834  SER B C   1 
ATOM   13294 O  O   . SER B 1 834 ? 152.276 165.583 161.546 1.00 67.75  ? 834  SER B O   1 
ATOM   13295 C  CB  . SER B 1 834 ? 151.777 164.803 164.688 1.00 67.75  ? 834  SER B CB  1 
ATOM   13296 O  OG  . SER B 1 834 ? 152.679 163.752 164.985 1.00 67.75  ? 834  SER B OG  1 
ATOM   13297 N  N   . TRP B 1 835 ? 154.131 164.787 162.564 1.00 69.36  ? 835  TRP B N   1 
ATOM   13298 C  CA  . TRP B 1 835 ? 154.777 164.306 161.348 1.00 69.36  ? 835  TRP B CA  1 
ATOM   13299 C  C   . TRP B 1 835 ? 153.887 163.366 160.534 1.00 69.36  ? 835  TRP B C   1 
ATOM   13300 O  O   . TRP B 1 835 ? 153.816 163.521 159.308 1.00 69.36  ? 835  TRP B O   1 
ATOM   13301 C  CB  . TRP B 1 835 ? 156.105 163.620 161.686 1.00 69.36  ? 835  TRP B CB  1 
ATOM   13302 C  CG  . TRP B 1 835 ? 157.203 164.578 162.028 1.00 69.36  ? 835  TRP B CG  1 
ATOM   13303 C  CD1 . TRP B 1 835 ? 157.174 165.551 162.984 1.00 69.36  ? 835  TRP B CD1 1 
ATOM   13304 C  CD2 . TRP B 1 835 ? 158.495 164.654 161.415 1.00 69.36  ? 835  TRP B CD2 1 
ATOM   13305 N  NE1 . TRP B 1 835 ? 158.369 166.228 163.004 1.00 69.36  ? 835  TRP B NE1 1 
ATOM   13306 C  CE2 . TRP B 1 835 ? 159.197 165.697 162.051 1.00 69.36  ? 835  TRP B CE2 1 
ATOM   13307 C  CE3 . TRP B 1 835 ? 159.126 163.942 160.391 1.00 69.36  ? 835  TRP B CE3 1 
ATOM   13308 C  CZ2 . TRP B 1 835 ? 160.498 166.045 161.696 1.00 69.36  ? 835  TRP B CZ2 1 
ATOM   13309 C  CZ3 . TRP B 1 835 ? 160.417 164.289 160.041 1.00 69.36  ? 835  TRP B CZ3 1 
ATOM   13310 C  CH2 . TRP B 1 835 ? 161.089 165.331 160.691 1.00 69.36  ? 835  TRP B CH2 1 
ATOM   13311 N  N   . PRO B 1 836 ? 153.214 162.376 161.142 1.00 67.63  ? 836  PRO B N   1 
ATOM   13312 C  CA  . PRO B 1 836 ? 152.299 161.543 160.339 1.00 67.63  ? 836  PRO B CA  1 
ATOM   13313 C  C   . PRO B 1 836 ? 151.198 162.335 159.652 1.00 67.63  ? 836  PRO B C   1 
ATOM   13314 O  O   . PRO B 1 836 ? 150.854 162.038 158.502 1.00 67.63  ? 836  PRO B O   1 
ATOM   13315 C  CB  . PRO B 1 836 ? 151.742 160.551 161.369 1.00 67.63  ? 836  PRO B CB  1 
ATOM   13316 C  CG  . PRO B 1 836 ? 152.785 160.468 162.407 1.00 67.63  ? 836  PRO B CG  1 
ATOM   13317 C  CD  . PRO B 1 836 ? 153.339 161.854 162.516 1.00 67.63  ? 836  PRO B CD  1 
ATOM   13318 N  N   . LEU B 1 837 ? 150.644 163.349 160.321 1.00 66.87  ? 837  LEU B N   1 
ATOM   13319 C  CA  . LEU B 1 837 ? 149.581 164.138 159.706 1.00 66.87  ? 837  LEU B CA  1 
ATOM   13320 C  C   . LEU B 1 837 ? 150.100 164.916 158.503 1.00 66.87  ? 837  LEU B C   1 
ATOM   13321 O  O   . LEU B 1 837 ? 149.453 164.950 157.450 1.00 66.87  ? 837  LEU B O   1 
ATOM   13322 C  CB  . LEU B 1 837 ? 148.961 165.088 160.729 1.00 66.87  ? 837  LEU B CB  1 
ATOM   13323 C  CG  . LEU B 1 837 ? 147.927 166.049 160.138 1.00 66.87  ? 837  LEU B CG  1 
ATOM   13324 C  CD1 . LEU B 1 837 ? 146.826 165.282 159.421 1.00 66.87  ? 837  LEU B CD1 1 
ATOM   13325 C  CD2 . LEU B 1 837 ? 147.342 166.953 161.207 1.00 66.87  ? 837  LEU B CD2 1 
ATOM   13326 N  N   . MET B 1 838 ? 151.266 165.550 158.641 1.00 71.24  ? 838  MET B N   1 
ATOM   13327 C  CA  . MET B 1 838 ? 151.845 166.281 157.519 1.00 71.24  ? 838  MET B CA  1 
ATOM   13328 C  C   . MET B 1 838 ? 152.187 165.340 156.370 1.00 71.24  ? 838  MET B C   1 
ATOM   13329 O  O   . MET B 1 838 ? 151.968 165.672 155.198 1.00 71.24  ? 838  MET B O   1 
ATOM   13330 C  CB  . MET B 1 838 ? 153.087 167.045 157.977 1.00 71.24  ? 838  MET B CB  1 
ATOM   13331 C  CG  . MET B 1 838 ? 152.804 168.452 158.475 1.00 71.24  ? 838  MET B CG  1 
ATOM   13332 S  SD  . MET B 1 838 ? 154.264 169.242 159.178 1.00 71.24  ? 838  MET B SD  1 
ATOM   13333 C  CE  . MET B 1 838 ? 153.512 170.425 160.292 1.00 71.24  ? 838  MET B CE  1 
ATOM   13334 N  N   . ILE B 1 839 ? 152.725 164.161 156.690 1.00 68.94  ? 839  ILE B N   1 
ATOM   13335 C  CA  . ILE B 1 839 ? 153.072 163.184 155.659 1.00 68.94  ? 839  ILE B CA  1 
ATOM   13336 C  C   . ILE B 1 839 ? 151.823 162.760 154.896 1.00 68.94  ? 839  ILE B C   1 
ATOM   13337 O  O   . ILE B 1 839 ? 151.809 162.714 153.660 1.00 68.94  ? 839  ILE B O   1 
ATOM   13338 C  CB  . ILE B 1 839 ? 153.788 161.975 156.284 1.00 68.94  ? 839  ILE B CB  1 
ATOM   13339 C  CG1 . ILE B 1 839 ? 155.251 162.316 156.575 1.00 68.94  ? 839  ILE B CG1 1 
ATOM   13340 C  CG2 . ILE B 1 839 ? 153.687 160.757 155.379 1.00 68.94  ? 839  ILE B CG2 1 
ATOM   13341 C  CD1 . ILE B 1 839 ? 156.014 161.204 157.261 1.00 68.94  ? 839  ILE B CD1 1 
ATOM   13342 N  N   . MET B 1 840 ? 150.750 162.453 155.629 1.00 67.30  ? 840  MET B N   1 
ATOM   13343 C  CA  . MET B 1 840 ? 149.505 162.050 154.983 1.00 67.30  ? 840  MET B CA  1 
ATOM   13344 C  C   . MET B 1 840 ? 148.927 163.183 154.146 1.00 67.30  ? 840  MET B C   1 
ATOM   13345 O  O   . MET B 1 840 ? 148.427 162.952 153.040 1.00 67.30  ? 840  MET B O   1 
ATOM   13346 C  CB  . MET B 1 840 ? 148.495 161.582 156.029 1.00 67.30  ? 840  MET B CB  1 
ATOM   13347 C  CG  . MET B 1 840 ? 148.828 160.235 156.649 1.00 67.30  ? 840  MET B CG  1 
ATOM   13348 S  SD  . MET B 1 840 ? 149.106 158.941 155.425 1.00 67.30  ? 840  MET B SD  1 
ATOM   13349 C  CE  . MET B 1 840 ? 147.562 158.994 154.518 1.00 67.30  ? 840  MET B CE  1 
ATOM   13350 N  N   . THR B 1 841 ? 148.988 164.415 154.656 1.00 68.45  ? 841  THR B N   1 
ATOM   13351 C  CA  . THR B 1 841 ? 148.493 165.561 153.900 1.00 68.45  ? 841  THR B CA  1 
ATOM   13352 C  C   . THR B 1 841 ? 149.232 165.704 152.576 1.00 68.45  ? 841  THR B C   1 
ATOM   13353 O  O   . THR B 1 841 ? 148.611 165.839 151.515 1.00 68.45  ? 841  THR B O   1 
ATOM   13354 C  CB  . THR B 1 841 ? 148.634 166.836 154.733 1.00 68.45  ? 841  THR B CB  1 
ATOM   13355 O  OG1 . THR B 1 841 ? 147.963 166.667 155.989 1.00 68.45  ? 841  THR B OG1 1 
ATOM   13356 C  CG2 . THR B 1 841 ? 148.043 168.028 153.999 1.00 68.45  ? 841  THR B CG2 1 
ATOM   13357 N  N   . VAL B 1 842 ? 150.565 165.658 152.619 1.00 70.59  ? 842  VAL B N   1 
ATOM   13358 C  CA  . VAL B 1 842 ? 151.355 165.820 151.401 1.00 70.59  ? 842  VAL B CA  1 
ATOM   13359 C  C   . VAL B 1 842 ? 151.089 164.672 150.432 1.00 70.59  ? 842  VAL B C   1 
ATOM   13360 O  O   . VAL B 1 842 ? 150.935 164.885 149.223 1.00 70.59  ? 842  VAL B O   1 
ATOM   13361 C  CB  . VAL B 1 842 ? 152.851 165.941 151.739 1.00 70.59  ? 842  VAL B CB  1 
ATOM   13362 C  CG1 . VAL B 1 842 ? 153.671 166.051 150.467 1.00 70.59  ? 842  VAL B CG1 1 
ATOM   13363 C  CG2 . VAL B 1 842 ? 153.094 167.153 152.623 1.00 70.59  ? 842  VAL B CG2 1 
ATOM   13364 N  N   . ILE B 1 843 ? 151.029 163.440 150.945 1.00 70.10  ? 843  ILE B N   1 
ATOM   13365 C  CA  . ILE B 1 843 ? 150.832 162.282 150.074 1.00 70.10  ? 843  ILE B CA  1 
ATOM   13366 C  C   . ILE B 1 843 ? 149.468 162.344 149.398 1.00 70.10  ? 843  ILE B C   1 
ATOM   13367 O  O   . ILE B 1 843 ? 149.336 162.082 148.196 1.00 70.10  ? 843  ILE B O   1 
ATOM   13368 C  CB  . ILE B 1 843 ? 151.013 160.975 150.867 1.00 70.10  ? 843  ILE B CB  1 
ATOM   13369 C  CG1 . ILE B 1 843 ? 152.491 160.754 151.193 1.00 70.10  ? 843  ILE B CG1 1 
ATOM   13370 C  CG2 . ILE B 1 843 ? 150.453 159.792 150.094 1.00 70.10  ? 843  ILE B CG2 1 
ATOM   13371 C  CD1 . ILE B 1 843 ? 152.755 159.526 152.035 1.00 70.10  ? 843  ILE B CD1 1 
ATOM   13372 N  N   . VAL B 1 844 ? 148.430 162.696 150.159 1.00 70.07  ? 844  VAL B N   1 
ATOM   13373 C  CA  . VAL B 1 844 ? 147.085 162.757 149.594 1.00 70.07  ? 844  VAL B CA  1 
ATOM   13374 C  C   . VAL B 1 844 ? 146.975 163.905 148.599 1.00 70.07  ? 844  VAL B C   1 
ATOM   13375 O  O   . VAL B 1 844 ? 146.305 163.791 147.566 1.00 70.07  ? 844  VAL B O   1 
ATOM   13376 C  CB  . VAL B 1 844 ? 146.037 162.863 150.716 1.00 70.07  ? 844  VAL B CB  1 
ATOM   13377 C  CG1 . VAL B 1 844 ? 144.670 163.208 150.148 1.00 70.07  ? 844  VAL B CG1 1 
ATOM   13378 C  CG2 . VAL B 1 844 ? 145.972 161.552 151.477 1.00 70.07  ? 844  VAL B CG2 1 
ATOM   13379 N  N   . MET B 1 845 ? 147.639 165.028 148.886 1.00 74.57  ? 845  MET B N   1 
ATOM   13380 C  CA  . MET B 1 845 ? 147.664 166.127 147.927 1.00 74.57  ? 845  MET B CA  1 
ATOM   13381 C  C   . MET B 1 845 ? 148.327 165.695 146.624 1.00 74.57  ? 845  MET B C   1 
ATOM   13382 O  O   . MET B 1 845 ? 147.841 166.008 145.530 1.00 74.57  ? 845  MET B O   1 
ATOM   13383 C  CB  . MET B 1 845 ? 148.390 167.329 148.531 1.00 74.57  ? 845  MET B CB  1 
ATOM   13384 C  CG  . MET B 1 845 ? 147.502 168.241 149.356 1.00 74.57  ? 845  MET B CG  1 
ATOM   13385 S  SD  . MET B 1 845 ? 148.452 169.338 150.423 1.00 74.57  ? 845  MET B SD  1 
ATOM   13386 C  CE  . MET B 1 845 ? 149.139 170.472 149.219 1.00 74.57  ? 845  MET B CE  1 
ATOM   13387 N  N   . ILE B 1 846 ? 149.438 164.961 146.726 1.00 73.06  ? 846  ILE B N   1 
ATOM   13388 C  CA  . ILE B 1 846 ? 150.133 164.476 145.535 1.00 73.06  ? 846  ILE B CA  1 
ATOM   13389 C  C   . ILE B 1 846 ? 149.245 163.518 144.752 1.00 73.06  ? 846  ILE B C   1 
ATOM   13390 O  O   . ILE B 1 846 ? 149.177 163.575 143.518 1.00 73.06  ? 846  ILE B O   1 
ATOM   13391 C  CB  . ILE B 1 846 ? 151.470 163.820 145.932 1.00 73.06  ? 846  ILE B CB  1 
ATOM   13392 C  CG1 . ILE B 1 846 ? 152.492 164.889 146.320 1.00 73.06  ? 846  ILE B CG1 1 
ATOM   13393 C  CG2 . ILE B 1 846 ? 152.005 162.955 144.802 1.00 73.06  ? 846  ILE B CG2 1 
ATOM   13394 C  CD1 . ILE B 1 846 ? 153.857 164.333 146.664 1.00 73.06  ? 846  ILE B CD1 1 
ATOM   13395 N  N   . VAL B 1 847 ? 148.555 162.619 145.457 1.00 73.78  ? 847  VAL B N   1 
ATOM   13396 C  CA  . VAL B 1 847 ? 147.672 161.663 144.791 1.00 73.78  ? 847  VAL B CA  1 
ATOM   13397 C  C   . VAL B 1 847 ? 146.537 162.389 144.078 1.00 73.78  ? 847  VAL B C   1 
ATOM   13398 O  O   . VAL B 1 847 ? 146.192 162.062 142.935 1.00 73.78  ? 847  VAL B O   1 
ATOM   13399 C  CB  . VAL B 1 847 ? 147.139 160.633 145.805 1.00 73.78  ? 847  VAL B CB  1 
ATOM   13400 C  CG1 . VAL B 1 847 ? 145.987 159.842 145.208 1.00 73.78  ? 847  VAL B CG1 1 
ATOM   13401 C  CG2 . VAL B 1 847 ? 148.256 159.700 146.243 1.00 73.78  ? 847  VAL B CG2 1 
ATOM   13402 N  N   . GLY B 1 848 ? 145.943 163.386 144.736 1.00 76.34  ? 848  GLY B N   1 
ATOM   13403 C  CA  . GLY B 1 848 ? 144.877 164.144 144.103 1.00 76.34  ? 848  GLY B CA  1 
ATOM   13404 C  C   . GLY B 1 848 ? 145.352 164.917 142.888 1.00 76.34  ? 848  GLY B C   1 
ATOM   13405 O  O   . GLY B 1 848 ? 144.639 165.018 141.887 1.00 76.34  ? 848  GLY B O   1 
ATOM   13406 N  N   . ILE B 1 849 ? 146.560 165.481 142.962 1.00 78.11  ? 849  ILE B N   1 
ATOM   13407 C  CA  . ILE B 1 849 ? 147.119 166.185 141.812 1.00 78.11  ? 849  ILE B CA  1 
ATOM   13408 C  C   . ILE B 1 849 ? 147.365 165.219 140.659 1.00 78.11  ? 849  ILE B C   1 
ATOM   13409 O  O   . ILE B 1 849 ? 147.057 165.524 139.500 1.00 78.11  ? 849  ILE B O   1 
ATOM   13410 C  CB  . ILE B 1 849 ? 148.407 166.925 142.216 1.00 78.11  ? 849  ILE B CB  1 
ATOM   13411 C  CG1 . ILE B 1 849 ? 148.076 168.141 143.081 1.00 78.11  ? 849  ILE B CG1 1 
ATOM   13412 C  CG2 . ILE B 1 849 ? 149.195 167.347 140.985 1.00 78.11  ? 849  ILE B CG2 1 
ATOM   13413 C  CD1 . ILE B 1 849 ? 149.295 168.827 143.659 1.00 78.11  ? 849  ILE B CD1 1 
ATOM   13414 N  N   . ALA B 1 850 ? 147.912 164.040 140.954 1.00 80.93  ? 850  ALA B N   1 
ATOM   13415 C  CA  . ALA B 1 850 ? 148.294 163.095 139.913 1.00 80.93  ? 850  ALA B CA  1 
ATOM   13416 C  C   . ALA B 1 850 ? 147.126 162.279 139.374 1.00 80.93  ? 850  ALA B C   1 
ATOM   13417 O  O   . ALA B 1 850 ? 147.283 161.625 138.338 1.00 80.93  ? 850  ALA B O   1 
ATOM   13418 C  CB  . ALA B 1 850 ? 149.376 162.149 140.437 1.00 80.93  ? 850  ALA B CB  1 
ATOM   13419 N  N   . LEU B 1 851 ? 145.975 162.288 140.046 1.00 83.80  ? 851  LEU B N   1 
ATOM   13420 C  CA  . LEU B 1 851 ? 144.837 161.508 139.560 1.00 83.80  ? 851  LEU B CA  1 
ATOM   13421 C  C   . LEU B 1 851 ? 144.360 161.942 138.178 1.00 83.80  ? 851  LEU B C   1 
ATOM   13422 O  O   . LEU B 1 851 ? 144.146 161.063 137.325 1.00 83.80  ? 851  LEU B O   1 
ATOM   13423 C  CB  . LEU B 1 851 ? 143.700 161.555 140.587 1.00 83.80  ? 851  LEU B CB  1 
ATOM   13424 C  CG  . LEU B 1 851 ? 142.703 160.397 140.510 1.00 83.80  ? 851  LEU B CG  1 
ATOM   13425 C  CD1 . LEU B 1 851 ? 143.368 159.087 140.899 1.00 83.80  ? 851  LEU B CD1 1 
ATOM   13426 C  CD2 . LEU B 1 851 ? 141.494 160.669 141.387 1.00 83.80  ? 851  LEU B CD2 1 
ATOM   13427 N  N   . PRO B 1 852 ? 144.161 163.233 137.882 1.00 89.34  ? 852  PRO B N   1 
ATOM   13428 C  CA  . PRO B 1 852 ? 143.785 163.607 136.508 1.00 89.34  ? 852  PRO B CA  1 
ATOM   13429 C  C   . PRO B 1 852 ? 144.822 163.229 135.464 1.00 89.34  ? 852  PRO B C   1 
ATOM   13430 O  O   . PRO B 1 852 ? 144.451 162.953 134.317 1.00 89.34  ? 852  PRO B O   1 
ATOM   13431 C  CB  . PRO B 1 852 ? 143.605 165.129 136.593 1.00 89.34  ? 852  PRO B CB  1 
ATOM   13432 C  CG  . PRO B 1 852 ? 143.309 165.389 138.021 1.00 89.34  ? 852  PRO B CG  1 
ATOM   13433 C  CD  . PRO B 1 852 ? 144.149 164.407 138.773 1.00 89.34  ? 852  PRO B CD  1 
ATOM   13434 N  N   . PHE B 1 853 ? 146.106 163.213 135.816 1.00 88.92  ? 853  PHE B N   1 
ATOM   13435 C  CA  . PHE B 1 853 ? 147.156 162.854 134.873 1.00 88.92  ? 853  PHE B CA  1 
ATOM   13436 C  C   . PHE B 1 853 ? 147.431 161.357 134.829 1.00 88.92  ? 853  PHE B C   1 
ATOM   13437 O  O   . PHE B 1 853 ? 148.186 160.909 133.960 1.00 88.92  ? 853  PHE B O   1 
ATOM   13438 C  CB  . PHE B 1 853 ? 148.451 163.597 135.216 1.00 88.92  ? 853  PHE B CB  1 
ATOM   13439 C  CG  . PHE B 1 853 ? 148.311 165.092 135.209 1.00 88.92  ? 853  PHE B CG  1 
ATOM   13440 C  CD1 . PHE B 1 853 ? 147.499 165.721 134.281 1.00 88.92  ? 853  PHE B CD1 1 
ATOM   13441 C  CD2 . PHE B 1 853 ? 148.993 165.868 136.130 1.00 88.92  ? 853  PHE B CD2 1 
ATOM   13442 C  CE1 . PHE B 1 853 ? 147.369 167.095 134.273 1.00 88.92  ? 853  PHE B CE1 1 
ATOM   13443 C  CE2 . PHE B 1 853 ? 148.866 167.244 136.127 1.00 88.92  ? 853  PHE B CE2 1 
ATOM   13444 C  CZ  . PHE B 1 853 ? 148.053 167.858 135.197 1.00 88.92  ? 853  PHE B CZ  1 
ATOM   13445 N  N   . SER B 1 854 ? 146.847 160.582 135.735 1.00 91.32  ? 854  SER B N   1 
ATOM   13446 C  CA  . SER B 1 854 ? 147.050 159.145 135.758 1.00 91.32  ? 854  SER B CA  1 
ATOM   13447 C  C   . SER B 1 854 ? 146.236 158.469 134.660 1.00 91.32  ? 854  SER B C   1 
ATOM   13448 O  O   . SER B 1 854 ? 145.222 159.004 134.207 1.00 91.32  ? 854  SER B O   1 
ATOM   13449 C  CB  . SER B 1 854 ? 146.658 158.583 137.121 1.00 91.32  ? 854  SER B CB  1 
ATOM   13450 O  OG  . SER B 1 854 ? 145.257 158.392 137.208 1.00 91.32  ? 854  SER B OG  1 
ATOM   13451 N  N   . PRO B 1 855 ? 146.668 157.290 134.204 1.00 94.94  ? 855  PRO B N   1 
ATOM   13452 C  CA  . PRO B 1 855 ? 145.872 156.558 133.205 1.00 94.94  ? 855  PRO B CA  1 
ATOM   13453 C  C   . PRO B 1 855 ? 144.487 156.174 133.696 1.00 94.94  ? 855  PRO B C   1 
ATOM   13454 O  O   . PRO B 1 855 ? 143.589 155.968 132.870 1.00 94.94  ? 855  PRO B O   1 
ATOM   13455 C  CB  . PRO B 1 855 ? 146.726 155.316 132.911 1.00 94.94  ? 855  PRO B CB  1 
ATOM   13456 C  CG  . PRO B 1 855 ? 147.672 155.207 134.067 1.00 94.94  ? 855  PRO B CG  1 
ATOM   13457 C  CD  . PRO B 1 855 ? 147.939 156.611 134.502 1.00 94.94  ? 855  PRO B CD  1 
ATOM   13458 N  N   . LEU B 1 856 ? 144.284 156.067 135.011 1.00 92.42  ? 856  LEU B N   1 
ATOM   13459 C  CA  . LEU B 1 856 ? 142.963 155.757 135.543 1.00 92.42  ? 856  LEU B CA  1 
ATOM   13460 C  C   . LEU B 1 856 ? 141.967 156.886 135.319 1.00 92.42  ? 856  LEU B C   1 
ATOM   13461 O  O   . LEU B 1 856 ? 140.756 156.649 135.399 1.00 92.42  ? 856  LEU B O   1 
ATOM   13462 C  CB  . LEU B 1 856 ? 143.059 155.443 137.037 1.00 92.42  ? 856  LEU B CB  1 
ATOM   13463 C  CG  . LEU B 1 856 ? 143.450 154.015 137.421 1.00 92.42  ? 856  LEU B CG  1 
ATOM   13464 C  CD1 . LEU B 1 856 ? 143.587 153.889 138.930 1.00 92.42  ? 856  LEU B CD1 1 
ATOM   13465 C  CD2 . LEU B 1 856 ? 142.431 153.022 136.888 1.00 92.42  ? 856  LEU B CD2 1 
ATOM   13466 N  N   . ALA B 1 857 ? 142.448 158.100 135.038 1.00 90.50  ? 857  ALA B N   1 
ATOM   13467 C  CA  . ALA B 1 857 ? 141.556 159.247 134.895 1.00 90.50  ? 857  ALA B CA  1 
ATOM   13468 C  C   . ALA B 1 857 ? 140.537 159.026 133.786 1.00 90.50  ? 857  ALA B C   1 
ATOM   13469 O  O   . ALA B 1 857 ? 139.390 159.479 133.887 1.00 90.50  ? 857  ALA B O   1 
ATOM   13470 C  CB  . ALA B 1 857 ? 142.369 160.512 134.630 1.00 90.50  ? 857  ALA B CB  1 
ATOM   13471 N  N   . SER B 1 858 ? 140.937 158.337 132.716 1.00 89.73  ? 858  SER B N   1 
ATOM   13472 C  CA  . SER B 1 858 ? 139.995 158.028 131.646 1.00 89.73  ? 858  SER B CA  1 
ATOM   13473 C  C   . SER B 1 858 ? 138.863 157.146 132.153 1.00 89.73  ? 858  SER B C   1 
ATOM   13474 O  O   . SER B 1 858 ? 137.698 157.347 131.790 1.00 89.73  ? 858  SER B O   1 
ATOM   13475 C  CB  . SER B 1 858 ? 140.724 157.354 130.484 1.00 89.73  ? 858  SER B CB  1 
ATOM   13476 O  OG  . SER B 1 858 ? 141.287 156.117 130.887 1.00 89.73  ? 858  SER B OG  1 
ATOM   13477 N  N   . TYR B 1 859 ? 139.185 156.162 132.995 1.00 91.26  ? 859  TYR B N   1 
ATOM   13478 C  CA  . TYR B 1 859 ? 138.147 155.301 133.551 1.00 91.26  ? 859  TYR B CA  1 
ATOM   13479 C  C   . TYR B 1 859 ? 137.289 156.053 134.562 1.00 91.26  ? 859  TYR B C   1 
ATOM   13480 O  O   . TYR B 1 859 ? 136.086 155.792 134.679 1.00 91.26  ? 859  TYR B O   1 
ATOM   13481 C  CB  . TYR B 1 859 ? 138.778 154.064 134.189 1.00 91.26  ? 859  TYR B CB  1 
ATOM   13482 C  CG  . TYR B 1 859 ? 139.221 153.026 133.183 1.00 91.26  ? 859  TYR B CG  1 
ATOM   13483 C  CD1 . TYR B 1 859 ? 138.468 152.770 132.045 1.00 91.26  ? 859  TYR B CD1 1 
ATOM   13484 C  CD2 . TYR B 1 859 ? 140.390 152.302 133.372 1.00 91.26  ? 859  TYR B CD2 1 
ATOM   13485 C  CE1 . TYR B 1 859 ? 138.866 151.822 131.123 1.00 91.26  ? 859  TYR B CE1 1 
ATOM   13486 C  CE2 . TYR B 1 859 ? 140.797 151.351 132.454 1.00 91.26  ? 859  TYR B CE2 1 
ATOM   13487 C  CZ  . TYR B 1 859 ? 140.031 151.116 131.332 1.00 91.26  ? 859  TYR B CZ  1 
ATOM   13488 O  OH  . TYR B 1 859 ? 140.430 150.171 130.415 1.00 91.26  ? 859  TYR B OH  1 
ATOM   13489 N  N   . LEU B 1 860 ? 137.887 156.986 135.298 1.00 86.69  ? 860  LEU B N   1 
ATOM   13490 C  CA  . LEU B 1 860 ? 137.172 157.785 136.283 1.00 86.69  ? 860  LEU B CA  1 
ATOM   13491 C  C   . LEU B 1 860 ? 136.528 159.026 135.678 1.00 86.69  ? 860  LEU B C   1 
ATOM   13492 O  O   . LEU B 1 860 ? 136.072 159.897 136.427 1.00 86.69  ? 860  LEU B O   1 
ATOM   13493 C  CB  . LEU B 1 860 ? 138.116 158.190 137.418 1.00 86.69  ? 860  LEU B CB  1 
ATOM   13494 C  CG  . LEU B 1 860 ? 138.883 157.054 138.096 1.00 86.69  ? 860  LEU B CG  1 
ATOM   13495 C  CD1 . LEU B 1 860 ? 139.986 157.606 138.984 1.00 86.69  ? 860  LEU B CD1 1 
ATOM   13496 C  CD2 . LEU B 1 860 ? 137.939 156.170 138.895 1.00 86.69  ? 860  LEU B CD2 1 
ATOM   13497 N  N   . GLN B 1 861 ? 136.485 159.123 134.347 1.00 88.78  ? 861  GLN B N   1 
ATOM   13498 C  CA  . GLN B 1 861 ? 135.898 160.268 133.648 1.00 88.78  ? 861  GLN B CA  1 
ATOM   13499 C  C   . GLN B 1 861 ? 136.575 161.576 134.054 1.00 88.78  ? 861  GLN B C   1 
ATOM   13500 O  O   . GLN B 1 861 ? 135.919 162.597 134.271 1.00 88.78  ? 861  GLN B O   1 
ATOM   13501 C  CB  . GLN B 1 861 ? 134.386 160.341 133.876 1.00 88.78  ? 861  GLN B CB  1 
ATOM   13502 C  CG  . GLN B 1 861 ? 133.620 159.150 133.321 1.00 88.78  ? 861  GLN B CG  1 
ATOM   13503 C  CD  . GLN B 1 861 ? 132.120 159.371 133.318 1.00 88.78  ? 861  GLN B CD  1 
ATOM   13504 O  OE1 . GLN B 1 861 ? 131.572 159.978 132.398 1.00 88.78  ? 861  GLN B OE1 1 
ATOM   13505 N  NE2 . GLN B 1 861 ? 131.447 158.876 134.350 1.00 88.78  ? 861  GLN B NE2 1 
ATOM   13506 N  N   . LEU B 1 862 ? 137.900 161.543 134.157 1.00 87.15  ? 862  LEU B N   1 
ATOM   13507 C  CA  . LEU B 1 862 ? 138.701 162.706 134.515 1.00 87.15  ? 862  LEU B CA  1 
ATOM   13508 C  C   . LEU B 1 862 ? 139.591 163.086 133.340 1.00 87.15  ? 862  LEU B C   1 
ATOM   13509 O  O   . LEU B 1 862 ? 140.202 162.215 132.711 1.00 87.15  ? 862  LEU B O   1 
ATOM   13510 C  CB  . LEU B 1 862 ? 139.551 162.423 135.756 1.00 87.15  ? 862  LEU B CB  1 
ATOM   13511 C  CG  . LEU B 1 862 ? 138.829 162.399 137.104 1.00 87.15  ? 862  LEU B CG  1 
ATOM   13512 C  CD1 . LEU B 1 862 ? 139.785 161.987 138.210 1.00 87.15  ? 862  LEU B CD1 1 
ATOM   13513 C  CD2 . LEU B 1 862 ? 138.218 163.756 137.405 1.00 87.15  ? 862  LEU B CD2 1 
ATOM   13514 N  N   . GLN B 1 863 ? 139.662 164.381 133.048 1.00 91.49  ? 863  GLN B N   1 
ATOM   13515 C  CA  . GLN B 1 863 ? 140.441 164.896 131.931 1.00 91.49  ? 863  GLN B CA  1 
ATOM   13516 C  C   . GLN B 1 863 ? 141.690 165.598 132.449 1.00 91.49  ? 863  GLN B C   1 
ATOM   13517 O  O   . GLN B 1 863 ? 141.671 166.207 133.522 1.00 91.49  ? 863  GLN B O   1 
ATOM   13518 C  CB  . GLN B 1 863 ? 139.600 165.857 131.085 1.00 91.49  ? 863  GLN B CB  1 
ATOM   13519 C  CG  . GLN B 1 863 ? 140.360 166.579 129.983 1.00 91.49  ? 863  GLN B CG  1 
ATOM   13520 C  CD  . GLN B 1 863 ? 139.492 167.562 129.224 1.00 91.49  ? 863  GLN B CD  1 
ATOM   13521 O  OE1 . GLN B 1 863 ? 138.307 167.715 129.518 1.00 91.49  ? 863  GLN B OE1 1 
ATOM   13522 N  NE2 . GLN B 1 863 ? 140.079 168.234 128.241 1.00 91.49  ? 863  GLN B NE2 1 
ATOM   13523 N  N   . ALA B 1 864 ? 142.776 165.499 131.684 1.00 93.11  ? 864  ALA B N   1 
ATOM   13524 C  CA  . ALA B 1 864 ? 144.034 166.119 132.080 1.00 93.11  ? 864  ALA B CA  1 
ATOM   13525 C  C   . ALA B 1 864 ? 143.888 167.634 132.163 1.00 93.11  ? 864  ALA B C   1 
ATOM   13526 O  O   . ALA B 1 864 ? 143.126 168.247 131.410 1.00 93.11  ? 864  ALA B O   1 
ATOM   13527 C  CB  . ALA B 1 864 ? 145.140 165.750 131.092 1.00 93.11  ? 864  ALA B CB  1 
ATOM   13528 N  N   . LEU B 1 865 ? 144.629 168.237 133.095 1.00 94.35  ? 865  LEU B N   1 
ATOM   13529 C  CA  . LEU B 1 865 ? 144.560 169.664 133.387 1.00 94.35  ? 865  LEU B CA  1 
ATOM   13530 C  C   . LEU B 1 865 ? 145.697 170.402 132.701 1.00 94.35  ? 865  LEU B C   1 
ATOM   13531 O  O   . LEU B 1 865 ? 146.842 169.925 132.725 1.00 94.35  ? 865  LEU B O   1 
ATOM   13532 C  CB  . LEU B 1 865 ? 144.626 169.904 134.893 1.00 94.35  ? 865  LEU B CB  1 
ATOM   13533 C  CG  . LEU B 1 865 ? 143.309 169.947 135.673 1.00 94.35  ? 865  LEU B CG  1 
ATOM   13534 C  CD1 . LEU B 1 865 ? 142.506 168.672 135.486 1.00 94.35  ? 865  LEU B CD1 1 
ATOM   13535 C  CD2 . LEU B 1 865 ? 143.586 170.183 137.148 1.00 94.35  ? 865  LEU B CD2 1 
ATOM   13536 N  N   . PRO B 1 866 ? 145.431 171.550 132.083 1.00 99.22  ? 866  PRO B N   1 
ATOM   13537 C  CA  . PRO B 1 866 ? 146.514 172.329 131.473 1.00 99.22  ? 866  PRO B CA  1 
ATOM   13538 C  C   . PRO B 1 866 ? 147.437 172.921 132.527 1.00 99.22  ? 866  PRO B C   1 
ATOM   13539 O  O   . PRO B 1 866 ? 147.053 173.130 133.680 1.00 99.22  ? 866  PRO B O   1 
ATOM   13540 C  CB  . PRO B 1 866 ? 145.772 173.427 130.704 1.00 99.22  ? 866  PRO B CB  1 
ATOM   13541 C  CG  . PRO B 1 866 ? 144.470 173.565 131.417 1.00 99.22  ? 866  PRO B CG  1 
ATOM   13542 C  CD  . PRO B 1 866 ? 144.116 172.189 131.904 1.00 99.22  ? 866  PRO B CD  1 
ATOM   13543 N  N   . LEU B 1 867 ? 148.677 173.192 132.110 1.00 97.80  ? 867  LEU B N   1 
ATOM   13544 C  CA  . LEU B 1 867 ? 149.680 173.710 133.033 1.00 97.80  ? 867  LEU B CA  1 
ATOM   13545 C  C   . LEU B 1 867 ? 149.350 175.109 133.538 1.00 97.80  ? 867  LEU B C   1 
ATOM   13546 O  O   . LEU B 1 867 ? 149.839 175.498 134.604 1.00 97.80  ? 867  LEU B O   1 
ATOM   13547 C  CB  . LEU B 1 867 ? 151.057 173.715 132.367 1.00 97.80  ? 867  LEU B CB  1 
ATOM   13548 C  CG  . LEU B 1 867 ? 151.916 172.464 132.566 1.00 97.80  ? 867  LEU B CG  1 
ATOM   13549 C  CD1 . LEU B 1 867 ? 151.420 171.317 131.697 1.00 97.80  ? 867  LEU B CD1 1 
ATOM   13550 C  CD2 . LEU B 1 867 ? 153.379 172.766 132.281 1.00 97.80  ? 867  LEU B CD2 1 
ATOM   13551 N  N   . SER B 1 868 ? 148.536 175.872 132.806 1.00 98.21  ? 868  SER B N   1 
ATOM   13552 C  CA  . SER B 1 868 ? 148.153 177.202 133.261 1.00 98.21  ? 868  SER B CA  1 
ATOM   13553 C  C   . SER B 1 868 ? 147.203 177.166 134.450 1.00 98.21  ? 868  SER B C   1 
ATOM   13554 O  O   . SER B 1 868 ? 147.025 178.194 135.111 1.00 98.21  ? 868  SER B O   1 
ATOM   13555 C  CB  . SER B 1 868 ? 147.510 177.984 132.115 1.00 98.21  ? 868  SER B CB  1 
ATOM   13556 O  OG  . SER B 1 868 ? 146.450 177.249 131.529 1.00 98.21  ? 868  SER B OG  1 
ATOM   13557 N  N   . TYR B 1 869 ? 146.592 176.014 134.733 1.00 98.09  ? 869  TYR B N   1 
ATOM   13558 C  CA  . TYR B 1 869 ? 145.645 175.923 135.839 1.00 98.09  ? 869  TYR B CA  1 
ATOM   13559 C  C   . TYR B 1 869 ? 146.363 175.834 137.180 1.00 98.09  ? 869  TYR B C   1 
ATOM   13560 O  O   . TYR B 1 869 ? 145.780 176.150 138.225 1.00 98.09  ? 869  TYR B O   1 
ATOM   13561 C  CB  . TYR B 1 869 ? 144.731 174.717 135.633 1.00 98.09  ? 869  TYR B CB  1 
ATOM   13562 C  CG  . TYR B 1 869 ? 143.635 174.581 136.662 1.00 98.09  ? 869  TYR B CG  1 
ATOM   13563 C  CD1 . TYR B 1 869 ? 142.523 175.410 136.629 1.00 98.09  ? 869  TYR B CD1 1 
ATOM   13564 C  CD2 . TYR B 1 869 ? 143.705 173.618 137.658 1.00 98.09  ? 869  TYR B CD2 1 
ATOM   13565 C  CE1 . TYR B 1 869 ? 141.518 175.291 137.561 1.00 98.09  ? 869  TYR B CE1 1 
ATOM   13566 C  CE2 . TYR B 1 869 ? 142.700 173.488 138.596 1.00 98.09  ? 869  TYR B CE2 1 
ATOM   13567 C  CZ  . TYR B 1 869 ? 141.609 174.329 138.541 1.00 98.09  ? 869  TYR B CZ  1 
ATOM   13568 O  OH  . TYR B 1 869 ? 140.600 174.212 139.466 1.00 98.09  ? 869  TYR B OH  1 
ATOM   13569 N  N   . PHE B 1 870 ? 147.616 175.383 137.171 1.00 95.52  ? 870  PHE B N   1 
ATOM   13570 C  CA  . PHE B 1 870 ? 148.357 175.227 138.420 1.00 95.52  ? 870  PHE B CA  1 
ATOM   13571 C  C   . PHE B 1 870 ? 148.599 176.542 139.156 1.00 95.52  ? 870  PHE B C   1 
ATOM   13572 O  O   . PHE B 1 870 ? 148.393 176.570 140.383 1.00 95.52  ? 870  PHE B O   1 
ATOM   13573 C  CB  . PHE B 1 870 ? 149.681 174.501 138.143 1.00 95.52  ? 870  PHE B CB  1 
ATOM   13574 C  CG  . PHE B 1 870 ? 149.546 173.009 138.046 1.00 95.52  ? 870  PHE B CG  1 
ATOM   13575 C  CD1 . PHE B 1 870 ? 148.956 172.426 136.937 1.00 95.52  ? 870  PHE B CD1 1 
ATOM   13576 C  CD2 . PHE B 1 870 ? 150.014 172.189 139.058 1.00 95.52  ? 870  PHE B CD2 1 
ATOM   13577 C  CE1 . PHE B 1 870 ? 148.830 171.053 136.841 1.00 95.52  ? 870  PHE B CE1 1 
ATOM   13578 C  CE2 . PHE B 1 870 ? 149.892 170.815 138.968 1.00 95.52  ? 870  PHE B CE2 1 
ATOM   13579 C  CZ  . PHE B 1 870 ? 149.299 170.247 137.858 1.00 95.52  ? 870  PHE B CZ  1 
ATOM   13580 N  N   . PRO B 1 871 ? 149.061 177.628 138.517 1.00 95.50  ? 871  PRO B N   1 
ATOM   13581 C  CA  . PRO B 1 871 ? 149.189 178.892 139.266 1.00 95.50  ? 871  PRO B CA  1 
ATOM   13582 C  C   . PRO B 1 871 ? 147.872 179.383 139.836 1.00 95.50  ? 871  PRO B C   1 
ATOM   13583 O  O   . PRO B 1 871 ? 147.838 179.898 140.961 1.00 95.50  ? 871  PRO B O   1 
ATOM   13584 C  CB  . PRO B 1 871 ? 149.753 179.863 138.219 1.00 95.50  ? 871  PRO B CB  1 
ATOM   13585 C  CG  . PRO B 1 871 ? 150.429 178.995 137.224 1.00 95.50  ? 871  PRO B CG  1 
ATOM   13586 C  CD  . PRO B 1 871 ? 149.587 177.761 137.146 1.00 95.50  ? 871  PRO B CD  1 
ATOM   13587 N  N   . TRP B 1 872 ? 146.778 179.229 139.087 1.00 94.80  ? 872  TRP B N   1 
ATOM   13588 C  CA  . TRP B 1 872 ? 145.474 179.640 139.595 1.00 94.80  ? 872  TRP B CA  1 
ATOM   13589 C  C   . TRP B 1 872 ? 145.076 178.815 140.810 1.00 94.80  ? 872  TRP B C   1 
ATOM   13590 O  O   . TRP B 1 872 ? 144.556 179.354 141.794 1.00 94.80  ? 872  TRP B O   1 
ATOM   13591 C  CB  . TRP B 1 872 ? 144.422 179.520 138.494 1.00 94.80  ? 872  TRP B CB  1 
ATOM   13592 C  CG  . TRP B 1 872 ? 144.536 180.580 137.444 1.00 94.80  ? 872  TRP B CG  1 
ATOM   13593 C  CD1 . TRP B 1 872 ? 145.133 180.463 136.223 1.00 94.80  ? 872  TRP B CD1 1 
ATOM   13594 C  CD2 . TRP B 1 872 ? 144.049 181.924 137.526 1.00 94.80  ? 872  TRP B CD2 1 
ATOM   13595 N  NE1 . TRP B 1 872 ? 145.043 181.649 135.537 1.00 94.80  ? 872  TRP B NE1 1 
ATOM   13596 C  CE2 . TRP B 1 872 ? 144.382 182.562 136.315 1.00 94.80  ? 872  TRP B CE2 1 
ATOM   13597 C  CE3 . TRP B 1 872 ? 143.362 182.648 138.505 1.00 94.80  ? 872  TRP B CE3 1 
ATOM   13598 C  CZ2 . TRP B 1 872 ? 144.051 183.890 136.057 1.00 94.80  ? 872  TRP B CZ2 1 
ATOM   13599 C  CZ3 . TRP B 1 872 ? 143.034 183.966 138.246 1.00 94.80  ? 872  TRP B CZ3 1 
ATOM   13600 C  CH2 . TRP B 1 872 ? 143.379 184.573 137.033 1.00 94.80  ? 872  TRP B CH2 1 
ATOM   13601 N  N   . LEU B 1 873 ? 145.318 177.504 140.761 1.00 91.74  ? 873  LEU B N   1 
ATOM   13602 C  CA  . LEU B 1 873 ? 145.005 176.647 141.900 1.00 91.74  ? 873  LEU B CA  1 
ATOM   13603 C  C   . LEU B 1 873 ? 145.837 177.029 143.117 1.00 91.74  ? 873  LEU B C   1 
ATOM   13604 O  O   . LEU B 1 873 ? 145.332 177.068 144.246 1.00 91.74  ? 873  LEU B O   1 
ATOM   13605 C  CB  . LEU B 1 873 ? 145.228 175.182 141.523 1.00 91.74  ? 873  LEU B CB  1 
ATOM   13606 C  CG  . LEU B 1 873 ? 144.907 174.123 142.576 1.00 91.74  ? 873  LEU B CG  1 
ATOM   13607 C  CD1 . LEU B 1 873 ? 144.193 172.956 141.927 1.00 91.74  ? 873  LEU B CD1 1 
ATOM   13608 C  CD2 . LEU B 1 873 ? 146.177 173.649 143.264 1.00 91.74  ? 873  LEU B CD2 1 
ATOM   13609 N  N   . VAL B 1 874 ? 147.125 177.309 142.905 1.00 89.71  ? 874  VAL B N   1 
ATOM   13610 C  CA  . VAL B 1 874 ? 147.993 177.700 144.012 1.00 89.71  ? 874  VAL B CA  1 
ATOM   13611 C  C   . VAL B 1 874 ? 147.515 179.008 144.627 1.00 89.71  ? 874  VAL B C   1 
ATOM   13612 O  O   . VAL B 1 874 ? 147.474 179.158 145.856 1.00 89.71  ? 874  VAL B O   1 
ATOM   13613 C  CB  . VAL B 1 874 ? 149.454 177.794 143.533 1.00 89.71  ? 874  VAL B CB  1 
ATOM   13614 C  CG1 . VAL B 1 874 ? 150.301 178.551 144.543 1.00 89.71  ? 874  VAL B CG1 1 
ATOM   13615 C  CG2 . VAL B 1 874 ? 150.019 176.403 143.290 1.00 89.71  ? 874  VAL B CG2 1 
ATOM   13616 N  N   . ALA B 1 875 ? 147.142 179.974 143.783 1.00 84.62  ? 875  ALA B N   1 
ATOM   13617 C  CA  . ALA B 1 875 ? 146.631 181.243 144.289 1.00 84.62  ? 875  ALA B CA  1 
ATOM   13618 C  C   . ALA B 1 875 ? 145.335 181.047 145.064 1.00 84.62  ? 875  ALA B C   1 
ATOM   13619 O  O   . ALA B 1 875 ? 145.129 181.674 146.109 1.00 84.62  ? 875  ALA B O   1 
ATOM   13620 C  CB  . ALA B 1 875 ? 146.424 182.224 143.136 1.00 84.62  ? 875  ALA B CB  1 
ATOM   13621 N  N   . ILE B 1 876 ? 144.449 180.181 144.568 1.00 84.36  ? 876  ILE B N   1 
ATOM   13622 C  CA  . ILE B 1 876 ? 143.189 179.922 145.260 1.00 84.36  ? 876  ILE B CA  1 
ATOM   13623 C  C   . ILE B 1 876 ? 143.453 179.312 146.631 1.00 84.36  ? 876  ILE B C   1 
ATOM   13624 O  O   . ILE B 1 876 ? 142.850 179.711 147.635 1.00 84.36  ? 876  ILE B O   1 
ATOM   13625 C  CB  . ILE B 1 876 ? 142.282 179.020 144.403 1.00 84.36  ? 876  ILE B CB  1 
ATOM   13626 C  CG1 . ILE B 1 876 ? 141.720 179.802 143.214 1.00 84.36  ? 876  ILE B CG1 1 
ATOM   13627 C  CG2 . ILE B 1 876 ? 141.154 178.440 145.242 1.00 84.36  ? 876  ILE B CG2 1 
ATOM   13628 C  CD1 . ILE B 1 876 ? 140.722 180.872 143.601 1.00 84.36  ? 876  ILE B CD1 1 
ATOM   13629 N  N   . LEU B 1 877 ? 144.362 178.336 146.693 1.00 80.47  ? 877  LEU B N   1 
ATOM   13630 C  CA  . LEU B 1 877 ? 144.683 177.703 147.970 1.00 80.47  ? 877  LEU B CA  1 
ATOM   13631 C  C   . LEU B 1 877 ? 145.292 178.702 148.948 1.00 80.47  ? 877  LEU B C   1 
ATOM   13632 O  O   . LEU B 1 877 ? 144.929 178.727 150.132 1.00 80.47  ? 877  LEU B O   1 
ATOM   13633 C  CB  . LEU B 1 877 ? 145.630 176.524 147.747 1.00 80.47  ? 877  LEU B CB  1 
ATOM   13634 C  CG  . LEU B 1 877 ? 145.055 175.329 146.986 1.00 80.47  ? 877  LEU B CG  1 
ATOM   13635 C  CD1 . LEU B 1 877 ? 146.026 174.160 147.004 1.00 80.47  ? 877  LEU B CD1 1 
ATOM   13636 C  CD2 . LEU B 1 877 ? 143.713 174.922 147.567 1.00 80.47  ? 877  LEU B CD2 1 
ATOM   13637 N  N   . ALA B 1 878 ? 146.224 179.532 148.471 1.00 83.48  ? 878  ALA B N   1 
ATOM   13638 C  CA  . ALA B 1 878 ? 146.845 180.524 149.343 1.00 83.48  ? 878  ALA B CA  1 
ATOM   13639 C  C   . ALA B 1 878 ? 145.821 181.527 149.855 1.00 83.48  ? 878  ALA B C   1 
ATOM   13640 O  O   . ALA B 1 878 ? 145.828 181.884 151.040 1.00 83.48  ? 878  ALA B O   1 
ATOM   13641 C  CB  . ALA B 1 878 ? 147.976 181.238 148.603 1.00 83.48  ? 878  ALA B CB  1 
ATOM   13642 N  N   . GLY B 1 879 ? 144.929 181.992 148.977 1.00 81.94  ? 879  GLY B N   1 
ATOM   13643 C  CA  . GLY B 1 879 ? 143.891 182.911 149.410 1.00 81.94  ? 879  GLY B CA  1 
ATOM   13644 C  C   . GLY B 1 879 ? 142.950 182.289 150.421 1.00 81.94  ? 879  GLY B C   1 
ATOM   13645 O  O   . GLY B 1 879 ? 142.554 182.935 151.392 1.00 81.94  ? 879  GLY B O   1 
ATOM   13646 N  N   . TYR B 1 880 ? 142.581 181.024 150.207 1.00 77.16  ? 880  TYR B N   1 
ATOM   13647 C  CA  . TYR B 1 880 ? 141.713 180.329 151.152 1.00 77.16  ? 880  TYR B CA  1 
ATOM   13648 C  C   . TYR B 1 880 ? 142.371 180.228 152.522 1.00 77.16  ? 880  TYR B C   1 
ATOM   13649 O  O   . TYR B 1 880 ? 141.748 180.528 153.551 1.00 77.16  ? 880  TYR B O   1 
ATOM   13650 C  CB  . TYR B 1 880 ? 141.370 178.944 150.601 1.00 77.16  ? 880  TYR B CB  1 
ATOM   13651 C  CG  . TYR B 1 880 ? 140.431 178.131 151.458 1.00 77.16  ? 880  TYR B CG  1 
ATOM   13652 C  CD1 . TYR B 1 880 ? 139.340 178.720 152.081 1.00 77.16  ? 880  TYR B CD1 1 
ATOM   13653 C  CD2 . TYR B 1 880 ? 140.627 176.769 151.631 1.00 77.16  ? 880  TYR B CD2 1 
ATOM   13654 C  CE1 . TYR B 1 880 ? 138.477 177.975 152.859 1.00 77.16  ? 880  TYR B CE1 1 
ATOM   13655 C  CE2 . TYR B 1 880 ? 139.771 176.016 152.405 1.00 77.16  ? 880  TYR B CE2 1 
ATOM   13656 C  CZ  . TYR B 1 880 ? 138.698 176.624 153.017 1.00 77.16  ? 880  TYR B CZ  1 
ATOM   13657 O  OH  . TYR B 1 880 ? 137.842 175.877 153.793 1.00 77.16  ? 880  TYR B OH  1 
ATOM   13658 N  N   . MET B 1 881 ? 143.644 179.827 152.551 1.00 78.80  ? 881  MET B N   1 
ATOM   13659 C  CA  . MET B 1 881 ? 144.352 179.706 153.821 1.00 78.80  ? 881  MET B CA  1 
ATOM   13660 C  C   . MET B 1 881 ? 144.472 181.056 154.519 1.00 78.80  ? 881  MET B C   1 
ATOM   13661 O  O   . MET B 1 881 ? 144.227 181.163 155.728 1.00 78.80  ? 881  MET B O   1 
ATOM   13662 C  CB  . MET B 1 881 ? 145.732 179.091 153.593 1.00 78.80  ? 881  MET B CB  1 
ATOM   13663 C  CG  . MET B 1 881 ? 145.693 177.647 153.120 1.00 78.80  ? 881  MET B CG  1 
ATOM   13664 S  SD  . MET B 1 881 ? 147.318 176.867 153.107 1.00 78.80  ? 881  MET B SD  1 
ATOM   13665 C  CE  . MET B 1 881 ? 147.239 175.882 154.600 1.00 78.80  ? 881  MET B CE  1 
ATOM   13666 N  N   . THR B 1 882 ? 144.834 182.103 153.774 1.00 79.84  ? 882  THR B N   1 
ATOM   13667 C  CA  . THR B 1 882 ? 144.982 183.420 154.386 1.00 79.84  ? 882  THR B CA  1 
ATOM   13668 C  C   . THR B 1 882 ? 143.651 183.940 154.915 1.00 79.84  ? 882  THR B C   1 
ATOM   13669 O  O   . THR B 1 882 ? 143.590 184.495 156.021 1.00 79.84  ? 882  THR B O   1 
ATOM   13670 C  CB  . THR B 1 882 ? 145.577 184.405 153.381 1.00 79.84  ? 882  THR B CB  1 
ATOM   13671 O  OG1 . THR B 1 882 ? 144.871 184.309 152.139 1.00 79.84  ? 882  THR B OG1 1 
ATOM   13672 C  CG2 . THR B 1 882 ? 147.050 184.100 153.148 1.00 79.84  ? 882  THR B CG2 1 
ATOM   13673 N  N   . LEU B 1 883 ? 142.574 183.771 154.144 1.00 78.21  ? 883  LEU B N   1 
ATOM   13674 C  CA  . LEU B 1 883 ? 141.275 184.263 154.583 1.00 78.21  ? 883  LEU B CA  1 
ATOM   13675 C  C   . LEU B 1 883 ? 140.801 183.527 155.828 1.00 78.21  ? 883  LEU B C   1 
ATOM   13676 O  O   . LEU B 1 883 ? 140.301 184.153 156.768 1.00 78.21  ? 883  LEU B O   1 
ATOM   13677 C  CB  . LEU B 1 883 ? 140.247 184.133 153.459 1.00 78.21  ? 883  LEU B CB  1 
ATOM   13678 C  CG  . LEU B 1 883 ? 138.838 184.605 153.828 1.00 78.21  ? 883  LEU B CG  1 
ATOM   13679 C  CD1 . LEU B 1 883 ? 138.875 186.031 154.355 1.00 78.21  ? 883  LEU B CD1 1 
ATOM   13680 C  CD2 . LEU B 1 883 ? 137.894 184.503 152.644 1.00 78.21  ? 883  LEU B CD2 1 
ATOM   13681 N  N   . THR B 1 884 ? 140.959 182.200 155.865 1.00 80.52  ? 884  THR B N   1 
ATOM   13682 C  CA  . THR B 1 884 ? 140.522 181.471 157.051 1.00 80.52  ? 884  THR B CA  1 
ATOM   13683 C  C   . THR B 1 884 ? 141.382 181.823 158.263 1.00 80.52  ? 884  THR B C   1 
ATOM   13684 O  O   . THR B 1 884 ? 140.872 181.907 159.388 1.00 80.52  ? 884  THR B O   1 
ATOM   13685 C  CB  . THR B 1 884 ? 140.513 179.961 156.784 1.00 80.52  ? 884  THR B CB  1 
ATOM   13686 O  OG1 . THR B 1 884 ? 139.785 179.294 157.823 1.00 80.52  ? 884  THR B OG1 1 
ATOM   13687 C  CG2 . THR B 1 884 ? 141.917 179.393 156.716 1.00 80.52  ? 884  THR B CG2 1 
ATOM   13688 N  N   . GLN B 1 885 ? 142.681 182.072 158.052 1.00 80.30  ? 885  GLN B N   1 
ATOM   13689 C  CA  . GLN B 1 885 ? 143.537 182.484 159.159 1.00 80.30  ? 885  GLN B CA  1 
ATOM   13690 C  C   . GLN B 1 885 ? 143.111 183.838 159.712 1.00 80.30  ? 885  GLN B C   1 
ATOM   13691 O  O   . GLN B 1 885 ? 143.066 184.030 160.932 1.00 80.30  ? 885  GLN B O   1 
ATOM   13692 C  CB  . GLN B 1 885 ? 144.996 182.520 158.704 1.00 80.30  ? 885  GLN B CB  1 
ATOM   13693 C  CG  . GLN B 1 885 ? 145.943 183.216 159.671 1.00 80.30  ? 885  GLN B CG  1 
ATOM   13694 C  CD  . GLN B 1 885 ? 145.846 182.668 161.081 1.00 80.30  ? 885  GLN B CD  1 
ATOM   13695 O  OE1 . GLN B 1 885 ? 146.162 181.505 161.331 1.00 80.30  ? 885  GLN B OE1 1 
ATOM   13696 N  NE2 . GLN B 1 885 ? 145.406 183.506 162.013 1.00 80.30  ? 885  GLN B NE2 1 
ATOM   13697 N  N   . LEU B 1 886 ? 142.787 184.788 158.832 1.00 80.34  ? 886  LEU B N   1 
ATOM   13698 C  CA  . LEU B 1 886 ? 142.365 186.104 159.303 1.00 80.34  ? 886  LEU B CA  1 
ATOM   13699 C  C   . LEU B 1 886 ? 140.956 186.076 159.885 1.00 80.34  ? 886  LEU B C   1 
ATOM   13700 O  O   . LEU B 1 886 ? 140.605 186.941 160.696 1.00 80.34  ? 886  LEU B O   1 
ATOM   13701 C  CB  . LEU B 1 886 ? 142.453 187.129 158.172 1.00 80.34  ? 886  LEU B CB  1 
ATOM   13702 C  CG  . LEU B 1 886 ? 143.787 187.857 157.961 1.00 80.34  ? 886  LEU B CG  1 
ATOM   13703 C  CD1 . LEU B 1 886 ? 144.114 188.722 159.169 1.00 80.34  ? 886  LEU B CD1 1 
ATOM   13704 C  CD2 . LEU B 1 886 ? 144.931 186.896 157.668 1.00 80.34  ? 886  LEU B CD2 1 
ATOM   13705 N  N   . VAL B 1 887 ? 140.138 185.099 159.490 1.00 79.77  ? 887  VAL B N   1 
ATOM   13706 C  CA  . VAL B 1 887 ? 138.764 185.022 159.976 1.00 79.77  ? 887  VAL B CA  1 
ATOM   13707 C  C   . VAL B 1 887 ? 138.647 184.264 161.297 1.00 79.77  ? 887  VAL B C   1 
ATOM   13708 O  O   . VAL B 1 887 ? 137.720 184.535 162.075 1.00 79.77  ? 887  VAL B O   1 
ATOM   13709 C  CB  . VAL B 1 887 ? 137.878 184.401 158.876 1.00 79.77  ? 887  VAL B CB  1 
ATOM   13710 C  CG1 . VAL B 1 887 ? 136.570 183.873 159.430 1.00 79.77  ? 887  VAL B CG1 1 
ATOM   13711 C  CG2 . VAL B 1 887 ? 137.599 185.429 157.790 1.00 79.77  ? 887  VAL B CG2 1 
ATOM   13712 N  N   . LYS B 1 888 ? 139.589 183.363 161.596 1.00 78.83  ? 888  LYS B N   1 
ATOM   13713 C  CA  . LYS B 1 888 ? 139.524 182.588 162.836 1.00 78.83  ? 888  LYS B CA  1 
ATOM   13714 C  C   . LYS B 1 888 ? 139.435 183.482 164.070 1.00 78.83  ? 888  LYS B C   1 
ATOM   13715 O  O   . LYS B 1 888 ? 138.882 183.079 165.101 1.00 78.83  ? 888  LYS B O   1 
ATOM   13716 C  CB  . LYS B 1 888 ? 140.745 181.675 162.940 1.00 78.83  ? 888  LYS B CB  1 
ATOM   13717 C  CG  . LYS B 1 888 ? 140.555 180.301 162.329 1.00 78.83  ? 888  LYS B CG  1 
ATOM   13718 C  CD  . LYS B 1 888 ? 141.893 179.654 162.020 1.00 78.83  ? 888  LYS B CD  1 
ATOM   13719 C  CE  . LYS B 1 888 ? 142.893 179.878 163.143 1.00 78.83  ? 888  LYS B CE  1 
ATOM   13720 N  NZ  . LYS B 1 888 ? 144.189 179.195 162.877 1.00 78.83  ? 888  LYS B NZ  1 
ATOM   13721 N  N   . GLY B 1 889 ? 139.991 184.693 163.988 1.00 83.93  ? 889  GLY B N   1 
ATOM   13722 C  CA  . GLY B 1 889 ? 139.956 185.592 165.131 1.00 83.93  ? 889  GLY B CA  1 
ATOM   13723 C  C   . GLY B 1 889 ? 138.548 185.973 165.545 1.00 83.93  ? 889  GLY B C   1 
ATOM   13724 O  O   . GLY B 1 889 ? 138.245 186.059 166.737 1.00 83.93  ? 889  GLY B O   1 
ATOM   13725 N  N   . PHE B 1 890 ? 137.670 186.217 164.569 1.00 85.71  ? 890  PHE B N   1 
ATOM   13726 C  CA  . PHE B 1 890 ? 136.292 186.576 164.893 1.00 85.71  ? 890  PHE B CA  1 
ATOM   13727 C  C   . PHE B 1 890 ? 135.573 185.430 165.592 1.00 85.71  ? 890  PHE B C   1 
ATOM   13728 O  O   . PHE B 1 890 ? 134.819 185.649 166.548 1.00 85.71  ? 890  PHE B O   1 
ATOM   13729 C  CB  . PHE B 1 890 ? 135.541 186.990 163.627 1.00 85.71  ? 890  PHE B CB  1 
ATOM   13730 C  CG  . PHE B 1 890 ? 135.891 188.366 163.133 1.00 85.71  ? 890  PHE B CG  1 
ATOM   13731 C  CD1 . PHE B 1 890 ? 137.190 188.682 162.767 1.00 85.71  ? 890  PHE B CD1 1 
ATOM   13732 C  CD2 . PHE B 1 890 ? 134.918 189.347 163.039 1.00 85.71  ? 890  PHE B CD2 1 
ATOM   13733 C  CE1 . PHE B 1 890 ? 137.510 189.947 162.314 1.00 85.71  ? 890  PHE B CE1 1 
ATOM   13734 C  CE2 . PHE B 1 890 ? 135.232 190.615 162.587 1.00 85.71  ? 890  PHE B CE2 1 
ATOM   13735 C  CZ  . PHE B 1 890 ? 136.530 190.915 162.225 1.00 85.71  ? 890  PHE B CZ  1 
ATOM   13736 N  N   . TYR B 1 891 ? 135.791 184.198 165.124 1.00 81.02  ? 891  TYR B N   1 
ATOM   13737 C  CA  . TYR B 1 891 ? 135.216 183.039 165.797 1.00 81.02  ? 891  TYR B CA  1 
ATOM   13738 C  C   . TYR B 1 891 ? 135.762 182.906 167.211 1.00 81.02  ? 891  TYR B C   1 
ATOM   13739 O  O   . TYR B 1 891 ? 135.027 182.545 168.139 1.00 81.02  ? 891  TYR B O   1 
ATOM   13740 C  CB  . TYR B 1 891 ? 135.498 181.771 164.992 1.00 81.02  ? 891  TYR B CB  1 
ATOM   13741 C  CG  . TYR B 1 891 ? 134.875 180.520 165.568 1.00 81.02  ? 891  TYR B CG  1 
ATOM   13742 C  CD1 . TYR B 1 891 ? 133.513 180.278 165.446 1.00 81.02  ? 891  TYR B CD1 1 
ATOM   13743 C  CD2 . TYR B 1 891 ? 135.650 179.578 166.231 1.00 81.02  ? 891  TYR B CD2 1 
ATOM   13744 C  CE1 . TYR B 1 891 ? 132.940 179.135 165.969 1.00 81.02  ? 891  TYR B CE1 1 
ATOM   13745 C  CE2 . TYR B 1 891 ? 135.086 178.432 166.757 1.00 81.02  ? 891  TYR B CE2 1 
ATOM   13746 C  CZ  . TYR B 1 891 ? 133.731 178.216 166.623 1.00 81.02  ? 891  TYR B CZ  1 
ATOM   13747 O  OH  . TYR B 1 891 ? 133.165 177.076 167.146 1.00 81.02  ? 891  TYR B OH  1 
ATOM   13748 N  N   . SER B 1 892 ? 137.055 183.185 167.393 1.00 86.61  ? 892  SER B N   1 
ATOM   13749 C  CA  . SER B 1 892 ? 137.641 183.126 168.728 1.00 86.61  ? 892  SER B CA  1 
ATOM   13750 C  C   . SER B 1 892 ? 137.009 184.156 169.658 1.00 86.61  ? 892  SER B C   1 
ATOM   13751 O  O   . SER B 1 892 ? 136.708 183.854 170.818 1.00 86.61  ? 892  SER B O   1 
ATOM   13752 C  CB  . SER B 1 892 ? 139.152 183.336 168.644 1.00 86.61  ? 892  SER B CB  1 
ATOM   13753 O  OG  . SER B 1 892 ? 139.769 182.294 167.909 1.00 86.61  ? 892  SER B OG  1 
ATOM   13754 N  N   . ARG B 1 893 ? 136.809 185.382 169.169 1.00 87.30  ? 893  ARG B N   1 
ATOM   13755 C  CA  . ARG B 1 893 ? 136.228 186.426 170.010 1.00 87.30  ? 893  ARG B CA  1 
ATOM   13756 C  C   . ARG B 1 893 ? 134.771 186.128 170.348 1.00 87.30  ? 893  ARG B C   1 
ATOM   13757 O  O   . ARG B 1 893 ? 134.375 186.174 171.518 1.00 87.30  ? 893  ARG B O   1 
ATOM   13758 C  CB  . ARG B 1 893 ? 136.344 187.793 169.329 1.00 87.30  ? 893  ARG B CB  1 
ATOM   13759 C  CG  . ARG B 1 893 ? 137.742 188.169 168.876 1.00 87.30  ? 893  ARG B CG  1 
ATOM   13760 C  CD  . ARG B 1 893 ? 138.625 188.564 170.049 1.00 87.30  ? 893  ARG B CD  1 
ATOM   13761 N  NE  . ARG B 1 893 ? 140.013 188.770 169.651 1.00 87.30  ? 893  ARG B NE  1 
ATOM   13762 C  CZ  . ARG B 1 893 ? 140.442 189.773 168.895 1.00 87.30  ? 893  ARG B CZ  1 
ATOM   13763 N  NH1 . ARG B 1 893 ? 139.617 190.705 168.446 1.00 87.30  ? 893  ARG B NH1 1 
ATOM   13764 N  NH2 . ARG B 1 893 ? 141.734 189.846 168.588 1.00 87.30  ? 893  ARG B NH2 1 
ATOM   13765 N  N   . ARG B 1 894 ? 133.955 185.821 169.336 1.00 89.93  ? 894  ARG B N   1 
ATOM   13766 C  CA  . ARG B 1 894 ? 132.515 185.736 169.563 1.00 89.93  ? 894  ARG B CA  1 
ATOM   13767 C  C   . ARG B 1 894 ? 132.136 184.489 170.355 1.00 89.93  ? 894  ARG B C   1 
ATOM   13768 O  O   . ARG B 1 894 ? 131.346 184.568 171.303 1.00 89.93  ? 894  ARG B O   1 
ATOM   13769 C  CB  . ARG B 1 894 ? 131.767 185.770 168.231 1.00 89.93  ? 894  ARG B CB  1 
ATOM   13770 C  CG  . ARG B 1 894 ? 130.270 185.539 168.367 1.00 89.93  ? 894  ARG B CG  1 
ATOM   13771 C  CD  . ARG B 1 894 ? 129.619 186.592 169.250 1.00 89.93  ? 894  ARG B CD  1 
ATOM   13772 N  NE  . ARG B 1 894 ? 128.225 186.276 169.538 1.00 89.93  ? 894  ARG B NE  1 
ATOM   13773 C  CZ  . ARG B 1 894 ? 127.202 186.617 168.765 1.00 89.93  ? 894  ARG B CZ  1 
ATOM   13774 N  NH1 . ARG B 1 894 ? 127.379 187.293 167.642 1.00 89.93  ? 894  ARG B NH1 1 
ATOM   13775 N  NH2 . ARG B 1 894 ? 125.971 186.272 169.130 1.00 89.93  ? 894  ARG B NH2 1 
ATOM   13776 N  N   . TYR B 1 895 ? 132.685 183.333 169.990 1.00 87.84  ? 895  TYR B N   1 
ATOM   13777 C  CA  . TYR B 1 895 ? 132.308 182.073 170.620 1.00 87.84  ? 895  TYR B CA  1 
ATOM   13778 C  C   . TYR B 1 895 ? 133.445 181.443 171.407 1.00 87.84  ? 895  TYR B C   1 
ATOM   13779 O  O   . TYR B 1 895 ? 133.212 180.899 172.493 1.00 87.84  ? 895  TYR B O   1 
ATOM   13780 C  CB  . TYR B 1 895 ? 131.795 181.084 169.560 1.00 87.84  ? 895  TYR B CB  1 
ATOM   13781 C  CG  . TYR B 1 895 ? 130.790 181.676 168.596 1.00 87.84  ? 895  TYR B CG  1 
ATOM   13782 C  CD1 . TYR B 1 895 ? 129.466 181.864 168.971 1.00 87.84  ? 895  TYR B CD1 1 
ATOM   13783 C  CD2 . TYR B 1 895 ? 131.164 182.039 167.309 1.00 87.84  ? 895  TYR B CD2 1 
ATOM   13784 C  CE1 . TYR B 1 895 ? 128.543 182.400 168.092 1.00 87.84  ? 895  TYR B CE1 1 
ATOM   13785 C  CE2 . TYR B 1 895 ? 130.249 182.576 166.422 1.00 87.84  ? 895  TYR B CE2 1 
ATOM   13786 C  CZ  . TYR B 1 895 ? 128.940 182.754 166.820 1.00 87.84  ? 895  TYR B CZ  1 
ATOM   13787 O  OH  . TYR B 1 895 ? 128.023 183.289 165.944 1.00 87.84  ? 895  TYR B OH  1 
ATOM   13788 N  N   . GLY B 1 896 ? 134.666 181.497 170.894 1.00 88.66  ? 896  GLY B N   1 
ATOM   13789 C  CA  . GLY B 1 896 ? 135.794 180.880 171.556 1.00 88.66  ? 896  GLY B CA  1 
ATOM   13790 C  C   . GLY B 1 896 ? 136.097 179.498 171.000 1.00 88.66  ? 896  GLY B C   1 
ATOM   13791 O  O   . GLY B 1 896 ? 135.237 178.807 170.449 1.00 88.66  ? 896  GLY B O   1 
ATOM   13792 N  N   . TRP B 1 897 ? 137.357 179.090 171.153 1.00 84.26  ? 897  TRP B N   1 
ATOM   13793 C  CA  . TRP B 1 897 ? 137.788 177.799 170.629 1.00 84.26  ? 897  TRP B CA  1 
ATOM   13794 C  C   . TRP B 1 897 ? 137.355 176.660 171.545 1.00 84.26  ? 897  TRP B C   1 
ATOM   13795 O  O   . TRP B 1 897 ? 136.638 175.747 171.124 1.00 84.26  ? 897  TRP B O   1 
ATOM   13796 C  CB  . TRP B 1 897 ? 139.307 177.790 170.441 1.00 84.26  ? 897  TRP B CB  1 
ATOM   13797 C  CG  . TRP B 1 897 ? 139.821 176.531 169.820 1.00 84.26  ? 897  TRP B CG  1 
ATOM   13798 C  CD1 . TRP B 1 897 ? 140.231 175.403 170.470 1.00 84.26  ? 897  TRP B CD1 1 
ATOM   13799 C  CD2 . TRP B 1 897 ? 139.984 176.271 168.422 1.00 84.26  ? 897  TRP B CD2 1 
ATOM   13800 N  NE1 . TRP B 1 897 ? 140.637 174.456 169.562 1.00 84.26  ? 897  TRP B NE1 1 
ATOM   13801 C  CE2 . TRP B 1 897 ? 140.496 174.965 168.297 1.00 84.26  ? 897  TRP B CE2 1 
ATOM   13802 C  CE3 . TRP B 1 897 ? 139.746 177.017 167.263 1.00 84.26  ? 897  TRP B CE3 1 
ATOM   13803 C  CZ2 . TRP B 1 897 ? 140.774 174.388 167.060 1.00 84.26  ? 897  TRP B CZ2 1 
ATOM   13804 C  CZ3 . TRP B 1 897 ? 140.023 176.443 166.037 1.00 84.26  ? 897  TRP B CZ3 1 
ATOM   13805 C  CH2 . TRP B 1 897 ? 140.532 175.142 165.945 1.00 84.26  ? 897  TRP B CH2 1 
ATOM   13806 N  N   . GLN B 1 898 ? 137.786 176.697 172.802 1.00 91.53  ? 898  GLN B N   1 
ATOM   13807 C  CA  . GLN B 1 898 ? 137.449 175.651 173.760 1.00 91.53  ? 898  GLN B CA  1 
ATOM   13808 C  C   . GLN B 1 898 ? 136.261 176.058 174.627 1.00 91.53  ? 898  GLN B C   1 
ATOM   13809 O  O   . GLN B 1 898 ? 135.565 175.212 175.189 1.00 91.53  ? 898  GLN B O   1 
ATOM   13810 C  CB  . GLN B 1 898 ? 138.657 175.323 174.640 1.00 91.53  ? 898  GLN B CB  1 
HETATM 13811 MG MG  . MG  C 2 .   ? 183.079 146.731 149.678 1.00 51.72  ? 1001 MG  A MG  1 
HETATM 13812 MG MG  . MG  D 2 .   ? 175.993 182.333 194.409 1.00 46.35  ? 1002 MG  A MG  1 
HETATM 13813 MG MG  . MG  E 2 .   ? 184.048 188.044 214.437 1.00 59.05  ? 1003 MG  A MG  1 
HETATM 13814 MG MG  . MG  F 2 .   ? 135.634 171.984 149.683 1.00 53.13  ? 1001 MG  B MG  1 
HETATM 13815 MG MG  . MG  G 2 .   ? 142.726 136.384 194.413 1.00 46.81  ? 1002 MG  B MG  1 
HETATM 13816 MG MG  . MG  H 2 .   ? 134.678 130.678 214.441 1.00 58.79  ? 1003 MG  B MG  1 
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