data_8UY9
# 
_entry.id   8UY9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UY9         pdb_00008uy9 10.2210/pdb8uy9/pdb 
WWPDB D_1000277101 ?            ?                   
EMDB  EMD-42796    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UY9 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-13 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'MgtA, Dimer'                                                   EMD-42794 'other EM volume'      
EMDB 'MgtA, Dimer, C1'                                               EMD-42795 'other EM volume'      
EMDB 'MgtA, Dimer, ATP bound'                                        EMD-42797 'other EM volume'      
EMDB 'MgtA, Dimer, Nonhydrolyzable ATP'                              EMD-42798 'other EM volume'      
EMDB 'MgtA, Dimer, ADP bound'                                        EMD-42799 'other EM volume'      
EMDB 'Magnesium transporter MgtA monomer from E. coli in 5 mM MgCl2' EMD-42796 'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 doreen.matthies@nih.gov      Doreen    Matthies ? 'principal investigator/group leader' 0000-0001-9221-4484 
3 storzg@mail.nih.gov          Gisela    Storz    ? 'principal investigator/group leader' 0000-0001-6698-1241 
4 alexander.sodt@nih.gov       Alexander Sodt     ? 'principal investigator/group leader' 0000-0002-5570-8212 
5 julian.langer@biophys.mpg.de Julian    Langer   D 'principal investigator/group leader' 0000-0002-5190-577X 
6 aravind@ncbi.nlm.nih.gov     Aravind   Iyer     ? 'principal investigator/group leader' 0000-0003-0771-253X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zeinert, R.'             1  0000-0003-3542-0227 
'Zhou, F.'                2  0000-0001-6657-7433 
'Cavalcanti Franco, P.H.' 3  0000-0002-3148-2319 
'Zoeller, J.'             4  0000-0002-7989-0768 
'Lessen, H.'              5  0000-0002-8764-8859 
'Iyer, A.'                6  0000-0003-0771-253X 
'Langer, J.D.'            7  0000-0002-5190-577X 
'Sodt, A.J.'              8  0000-0002-5570-8212 
'Storz, G.'               9  0000-0001-6698-1241 
'Matthies, D.'            10 0000-0001-9221-4484 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Magnesium Transporter MgtA revealed as a Dimeric P-type ATPase' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zeinert, R.'             1  0000-0003-3542-0227 
primary 'Zhou, F.'                2  0000-0001-6657-7433 
primary 'Cavalcanti Franco, P.H.' 3  0000-0002-3148-2319 
primary 'Zoeller, J.'             4  0000-0002-7989-0768 
primary 'Lessen, H.'              5  0000-0002-8764-8859 
primary 'Iyer, A.'                6  0000-0003-0771-253X 
primary 'Langer, J.D.'            7  0000-0002-5190-577X 
primary 'Sodt, A.J.'              8  0000-0002-5570-8212 
primary 'Storz, G.'               9  0000-0001-6698-1241 
primary 'Matthies, D.'            10 0000-0001-9221-4484 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Magnesium-transporting ATPase, P-type 1' 100393.062 1 ? ? ? ? 
2 non-polymer syn 'MAGNESIUM ION'                           24.305     1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQHHHHHH
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'MAGNESIUM ION' 
_pdbx_entity_nonpoly.comp_id     MG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PHE n 
1 3   LYS n 
1 4   GLU n 
1 5   ILE n 
1 6   PHE n 
1 7   THR n 
1 8   ARG n 
1 9   LEU n 
1 10  ILE n 
1 11  ARG n 
1 12  HIS n 
1 13  LEU n 
1 14  PRO n 
1 15  SER n 
1 16  ARG n 
1 17  LEU n 
1 18  VAL n 
1 19  HIS n 
1 20  ARG n 
1 21  ASP n 
1 22  PRO n 
1 23  LEU n 
1 24  PRO n 
1 25  GLY n 
1 26  ALA n 
1 27  GLN n 
1 28  GLN n 
1 29  THR n 
1 30  VAL n 
1 31  ASN n 
1 32  THR n 
1 33  VAL n 
1 34  VAL n 
1 35  PRO n 
1 36  PRO n 
1 37  SER n 
1 38  LEU n 
1 39  SER n 
1 40  ALA n 
1 41  HIS n 
1 42  CYS n 
1 43  LEU n 
1 44  LYS n 
1 45  MET n 
1 46  ALA n 
1 47  VAL n 
1 48  MET n 
1 49  PRO n 
1 50  GLU n 
1 51  GLU n 
1 52  GLU n 
1 53  LEU n 
1 54  TRP n 
1 55  LYS n 
1 56  THR n 
1 57  PHE n 
1 58  ASP n 
1 59  THR n 
1 60  HIS n 
1 61  PRO n 
1 62  GLU n 
1 63  GLY n 
1 64  LEU n 
1 65  ASN n 
1 66  GLN n 
1 67  ALA n 
1 68  GLU n 
1 69  VAL n 
1 70  GLU n 
1 71  SER n 
1 72  ALA n 
1 73  ARG n 
1 74  GLU n 
1 75  GLN n 
1 76  HIS n 
1 77  GLY n 
1 78  GLU n 
1 79  ASN n 
1 80  LYS n 
1 81  LEU n 
1 82  PRO n 
1 83  ALA n 
1 84  GLN n 
1 85  GLN n 
1 86  PRO n 
1 87  SER n 
1 88  PRO n 
1 89  TRP n 
1 90  TRP n 
1 91  VAL n 
1 92  HIS n 
1 93  LEU n 
1 94  TRP n 
1 95  VAL n 
1 96  CYS n 
1 97  TYR n 
1 98  ARG n 
1 99  ASN n 
1 100 PRO n 
1 101 PHE n 
1 102 ASN n 
1 103 ILE n 
1 104 LEU n 
1 105 LEU n 
1 106 THR n 
1 107 ILE n 
1 108 LEU n 
1 109 GLY n 
1 110 ALA n 
1 111 ILE n 
1 112 SER n 
1 113 TYR n 
1 114 ALA n 
1 115 THR n 
1 116 GLU n 
1 117 ASP n 
1 118 LEU n 
1 119 PHE n 
1 120 ALA n 
1 121 ALA n 
1 122 GLY n 
1 123 VAL n 
1 124 ILE n 
1 125 ALA n 
1 126 LEU n 
1 127 MET n 
1 128 VAL n 
1 129 ALA n 
1 130 ILE n 
1 131 SER n 
1 132 THR n 
1 133 LEU n 
1 134 LEU n 
1 135 ASN n 
1 136 PHE n 
1 137 ILE n 
1 138 GLN n 
1 139 GLU n 
1 140 ALA n 
1 141 ARG n 
1 142 SER n 
1 143 THR n 
1 144 LYS n 
1 145 ALA n 
1 146 ALA n 
1 147 ASP n 
1 148 ALA n 
1 149 LEU n 
1 150 LYS n 
1 151 ALA n 
1 152 MET n 
1 153 VAL n 
1 154 SER n 
1 155 ASN n 
1 156 THR n 
1 157 ALA n 
1 158 THR n 
1 159 VAL n 
1 160 LEU n 
1 161 ARG n 
1 162 VAL n 
1 163 ILE n 
1 164 ASN n 
1 165 ASP n 
1 166 LYS n 
1 167 GLY n 
1 168 GLU n 
1 169 ASN n 
1 170 GLY n 
1 171 TRP n 
1 172 LEU n 
1 173 GLU n 
1 174 ILE n 
1 175 PRO n 
1 176 ILE n 
1 177 ASP n 
1 178 GLN n 
1 179 LEU n 
1 180 VAL n 
1 181 PRO n 
1 182 GLY n 
1 183 ASP n 
1 184 ILE n 
1 185 ILE n 
1 186 LYS n 
1 187 LEU n 
1 188 ALA n 
1 189 ALA n 
1 190 GLY n 
1 191 ASP n 
1 192 MET n 
1 193 ILE n 
1 194 PRO n 
1 195 ALA n 
1 196 ASP n 
1 197 LEU n 
1 198 ARG n 
1 199 ILE n 
1 200 LEU n 
1 201 GLN n 
1 202 ALA n 
1 203 ARG n 
1 204 ASP n 
1 205 LEU n 
1 206 PHE n 
1 207 VAL n 
1 208 ALA n 
1 209 GLN n 
1 210 ALA n 
1 211 SER n 
1 212 LEU n 
1 213 THR n 
1 214 GLY n 
1 215 GLU n 
1 216 SER n 
1 217 LEU n 
1 218 PRO n 
1 219 VAL n 
1 220 GLU n 
1 221 LYS n 
1 222 ALA n 
1 223 ALA n 
1 224 THR n 
1 225 THR n 
1 226 ARG n 
1 227 GLN n 
1 228 PRO n 
1 229 GLU n 
1 230 HIS n 
1 231 SER n 
1 232 ASN n 
1 233 PRO n 
1 234 LEU n 
1 235 GLU n 
1 236 CYS n 
1 237 ASP n 
1 238 THR n 
1 239 LEU n 
1 240 CYS n 
1 241 PHE n 
1 242 MET n 
1 243 GLY n 
1 244 THR n 
1 245 THR n 
1 246 VAL n 
1 247 VAL n 
1 248 SER n 
1 249 GLY n 
1 250 THR n 
1 251 ALA n 
1 252 GLN n 
1 253 ALA n 
1 254 MET n 
1 255 VAL n 
1 256 ILE n 
1 257 ALA n 
1 258 THR n 
1 259 GLY n 
1 260 ALA n 
1 261 ASN n 
1 262 THR n 
1 263 TRP n 
1 264 PHE n 
1 265 GLY n 
1 266 GLN n 
1 267 LEU n 
1 268 ALA n 
1 269 GLY n 
1 270 ARG n 
1 271 VAL n 
1 272 SER n 
1 273 GLU n 
1 274 GLN n 
1 275 GLU n 
1 276 SER n 
1 277 GLU n 
1 278 PRO n 
1 279 ASN n 
1 280 ALA n 
1 281 PHE n 
1 282 GLN n 
1 283 GLN n 
1 284 GLY n 
1 285 ILE n 
1 286 SER n 
1 287 ARG n 
1 288 VAL n 
1 289 SER n 
1 290 MET n 
1 291 LEU n 
1 292 LEU n 
1 293 ILE n 
1 294 ARG n 
1 295 PHE n 
1 296 MET n 
1 297 LEU n 
1 298 VAL n 
1 299 MET n 
1 300 ALA n 
1 301 PRO n 
1 302 VAL n 
1 303 VAL n 
1 304 LEU n 
1 305 LEU n 
1 306 ILE n 
1 307 ASN n 
1 308 GLY n 
1 309 TYR n 
1 310 THR n 
1 311 LYS n 
1 312 GLY n 
1 313 ASP n 
1 314 TRP n 
1 315 TRP n 
1 316 GLU n 
1 317 ALA n 
1 318 ALA n 
1 319 LEU n 
1 320 PHE n 
1 321 ALA n 
1 322 LEU n 
1 323 SER n 
1 324 VAL n 
1 325 ALA n 
1 326 VAL n 
1 327 GLY n 
1 328 LEU n 
1 329 THR n 
1 330 PRO n 
1 331 GLU n 
1 332 MET n 
1 333 LEU n 
1 334 PRO n 
1 335 MET n 
1 336 ILE n 
1 337 VAL n 
1 338 THR n 
1 339 SER n 
1 340 THR n 
1 341 LEU n 
1 342 ALA n 
1 343 ARG n 
1 344 GLY n 
1 345 ALA n 
1 346 VAL n 
1 347 LYS n 
1 348 LEU n 
1 349 SER n 
1 350 LYS n 
1 351 GLN n 
1 352 LYS n 
1 353 VAL n 
1 354 ILE n 
1 355 VAL n 
1 356 LYS n 
1 357 HIS n 
1 358 LEU n 
1 359 ASP n 
1 360 ALA n 
1 361 ILE n 
1 362 GLN n 
1 363 ASN n 
1 364 PHE n 
1 365 GLY n 
1 366 ALA n 
1 367 MET n 
1 368 ASP n 
1 369 ILE n 
1 370 LEU n 
1 371 CYS n 
1 372 THR n 
1 373 ASP n 
1 374 LYS n 
1 375 THR n 
1 376 GLY n 
1 377 THR n 
1 378 LEU n 
1 379 THR n 
1 380 GLN n 
1 381 ASP n 
1 382 LYS n 
1 383 ILE n 
1 384 VAL n 
1 385 LEU n 
1 386 GLU n 
1 387 ASN n 
1 388 HIS n 
1 389 THR n 
1 390 ASP n 
1 391 ILE n 
1 392 SER n 
1 393 GLY n 
1 394 LYS n 
1 395 THR n 
1 396 SER n 
1 397 GLU n 
1 398 ARG n 
1 399 VAL n 
1 400 LEU n 
1 401 HIS n 
1 402 SER n 
1 403 ALA n 
1 404 TRP n 
1 405 LEU n 
1 406 ASN n 
1 407 SER n 
1 408 HIS n 
1 409 TYR n 
1 410 GLN n 
1 411 THR n 
1 412 GLY n 
1 413 LEU n 
1 414 LYS n 
1 415 ASN n 
1 416 LEU n 
1 417 LEU n 
1 418 ASP n 
1 419 THR n 
1 420 ALA n 
1 421 VAL n 
1 422 LEU n 
1 423 GLU n 
1 424 GLY n 
1 425 THR n 
1 426 ASP n 
1 427 GLU n 
1 428 GLU n 
1 429 SER n 
1 430 ALA n 
1 431 ARG n 
1 432 SER n 
1 433 LEU n 
1 434 ALA n 
1 435 SER n 
1 436 ARG n 
1 437 TRP n 
1 438 GLN n 
1 439 LYS n 
1 440 ILE n 
1 441 ASP n 
1 442 GLU n 
1 443 ILE n 
1 444 PRO n 
1 445 PHE n 
1 446 ASP n 
1 447 PHE n 
1 448 GLU n 
1 449 ARG n 
1 450 ARG n 
1 451 ARG n 
1 452 MET n 
1 453 SER n 
1 454 VAL n 
1 455 VAL n 
1 456 VAL n 
1 457 ALA n 
1 458 GLU n 
1 459 ASN n 
1 460 THR n 
1 461 GLU n 
1 462 HIS n 
1 463 HIS n 
1 464 GLN n 
1 465 LEU n 
1 466 VAL n 
1 467 CYS n 
1 468 LYS n 
1 469 GLY n 
1 470 ALA n 
1 471 LEU n 
1 472 GLN n 
1 473 GLU n 
1 474 ILE n 
1 475 LEU n 
1 476 ASN n 
1 477 VAL n 
1 478 CYS n 
1 479 SER n 
1 480 GLN n 
1 481 VAL n 
1 482 ARG n 
1 483 HIS n 
1 484 ASN n 
1 485 GLY n 
1 486 GLU n 
1 487 ILE n 
1 488 VAL n 
1 489 PRO n 
1 490 LEU n 
1 491 ASP n 
1 492 ASP n 
1 493 ILE n 
1 494 MET n 
1 495 LEU n 
1 496 ARG n 
1 497 LYS n 
1 498 ILE n 
1 499 LYS n 
1 500 ARG n 
1 501 VAL n 
1 502 THR n 
1 503 ASP n 
1 504 THR n 
1 505 LEU n 
1 506 ASN n 
1 507 ARG n 
1 508 GLN n 
1 509 GLY n 
1 510 LEU n 
1 511 ARG n 
1 512 VAL n 
1 513 VAL n 
1 514 ALA n 
1 515 VAL n 
1 516 ALA n 
1 517 THR n 
1 518 LYS n 
1 519 TYR n 
1 520 LEU n 
1 521 PRO n 
1 522 ALA n 
1 523 ARG n 
1 524 GLU n 
1 525 GLY n 
1 526 ASP n 
1 527 TYR n 
1 528 GLN n 
1 529 ARG n 
1 530 ALA n 
1 531 ASP n 
1 532 GLU n 
1 533 SER n 
1 534 ASP n 
1 535 LEU n 
1 536 ILE n 
1 537 LEU n 
1 538 GLU n 
1 539 GLY n 
1 540 TYR n 
1 541 ILE n 
1 542 ALA n 
1 543 PHE n 
1 544 LEU n 
1 545 ASP n 
1 546 PRO n 
1 547 PRO n 
1 548 LYS n 
1 549 GLU n 
1 550 THR n 
1 551 THR n 
1 552 ALA n 
1 553 PRO n 
1 554 ALA n 
1 555 LEU n 
1 556 LYS n 
1 557 ALA n 
1 558 LEU n 
1 559 LYS n 
1 560 ALA n 
1 561 SER n 
1 562 GLY n 
1 563 ILE n 
1 564 THR n 
1 565 VAL n 
1 566 LYS n 
1 567 ILE n 
1 568 LEU n 
1 569 THR n 
1 570 GLY n 
1 571 ASP n 
1 572 SER n 
1 573 GLU n 
1 574 LEU n 
1 575 VAL n 
1 576 ALA n 
1 577 ALA n 
1 578 LYS n 
1 579 VAL n 
1 580 CYS n 
1 581 HIS n 
1 582 GLU n 
1 583 VAL n 
1 584 GLY n 
1 585 LEU n 
1 586 ASP n 
1 587 ALA n 
1 588 GLY n 
1 589 GLU n 
1 590 VAL n 
1 591 VAL n 
1 592 ILE n 
1 593 GLY n 
1 594 SER n 
1 595 ASP n 
1 596 ILE n 
1 597 GLU n 
1 598 THR n 
1 599 LEU n 
1 600 SER n 
1 601 ASP n 
1 602 ASP n 
1 603 GLU n 
1 604 LEU n 
1 605 ALA n 
1 606 ASN n 
1 607 LEU n 
1 608 ALA n 
1 609 GLN n 
1 610 ARG n 
1 611 THR n 
1 612 THR n 
1 613 LEU n 
1 614 PHE n 
1 615 ALA n 
1 616 ARG n 
1 617 LEU n 
1 618 THR n 
1 619 PRO n 
1 620 MET n 
1 621 HIS n 
1 622 LYS n 
1 623 GLU n 
1 624 ARG n 
1 625 ILE n 
1 626 VAL n 
1 627 THR n 
1 628 LEU n 
1 629 LEU n 
1 630 LYS n 
1 631 ARG n 
1 632 GLU n 
1 633 GLY n 
1 634 HIS n 
1 635 VAL n 
1 636 VAL n 
1 637 GLY n 
1 638 PHE n 
1 639 MET n 
1 640 GLY n 
1 641 ASP n 
1 642 GLY n 
1 643 ILE n 
1 644 ASN n 
1 645 ASP n 
1 646 ALA n 
1 647 PRO n 
1 648 ALA n 
1 649 LEU n 
1 650 ARG n 
1 651 ALA n 
1 652 ALA n 
1 653 ASP n 
1 654 ILE n 
1 655 GLY n 
1 656 ILE n 
1 657 SER n 
1 658 VAL n 
1 659 ASP n 
1 660 GLY n 
1 661 ALA n 
1 662 VAL n 
1 663 ASP n 
1 664 ILE n 
1 665 ALA n 
1 666 ARG n 
1 667 GLU n 
1 668 ALA n 
1 669 ALA n 
1 670 ASP n 
1 671 ILE n 
1 672 ILE n 
1 673 LEU n 
1 674 LEU n 
1 675 GLU n 
1 676 LYS n 
1 677 SER n 
1 678 LEU n 
1 679 MET n 
1 680 VAL n 
1 681 LEU n 
1 682 GLU n 
1 683 GLU n 
1 684 GLY n 
1 685 VAL n 
1 686 ILE n 
1 687 GLU n 
1 688 GLY n 
1 689 ARG n 
1 690 ARG n 
1 691 THR n 
1 692 PHE n 
1 693 ALA n 
1 694 ASN n 
1 695 MET n 
1 696 LEU n 
1 697 LYS n 
1 698 TYR n 
1 699 ILE n 
1 700 LYS n 
1 701 MET n 
1 702 THR n 
1 703 ALA n 
1 704 SER n 
1 705 SER n 
1 706 ASN n 
1 707 PHE n 
1 708 GLY n 
1 709 ASN n 
1 710 VAL n 
1 711 PHE n 
1 712 SER n 
1 713 VAL n 
1 714 LEU n 
1 715 VAL n 
1 716 ALA n 
1 717 SER n 
1 718 ALA n 
1 719 PHE n 
1 720 LEU n 
1 721 PRO n 
1 722 PHE n 
1 723 LEU n 
1 724 PRO n 
1 725 MET n 
1 726 LEU n 
1 727 PRO n 
1 728 LEU n 
1 729 HIS n 
1 730 LEU n 
1 731 LEU n 
1 732 ILE n 
1 733 GLN n 
1 734 ASN n 
1 735 LEU n 
1 736 LEU n 
1 737 TYR n 
1 738 ASP n 
1 739 VAL n 
1 740 SER n 
1 741 GLN n 
1 742 VAL n 
1 743 ALA n 
1 744 ILE n 
1 745 PRO n 
1 746 PHE n 
1 747 ASP n 
1 748 ASN n 
1 749 VAL n 
1 750 ASP n 
1 751 ASP n 
1 752 GLU n 
1 753 GLN n 
1 754 ILE n 
1 755 GLN n 
1 756 LYS n 
1 757 PRO n 
1 758 GLN n 
1 759 ARG n 
1 760 TRP n 
1 761 ASN n 
1 762 PRO n 
1 763 ALA n 
1 764 ASP n 
1 765 LEU n 
1 766 GLY n 
1 767 ARG n 
1 768 PHE n 
1 769 MET n 
1 770 ILE n 
1 771 PHE n 
1 772 PHE n 
1 773 GLY n 
1 774 PRO n 
1 775 ILE n 
1 776 SER n 
1 777 SER n 
1 778 ILE n 
1 779 PHE n 
1 780 ASP n 
1 781 ILE n 
1 782 LEU n 
1 783 THR n 
1 784 PHE n 
1 785 CYS n 
1 786 LEU n 
1 787 MET n 
1 788 TRP n 
1 789 TRP n 
1 790 VAL n 
1 791 PHE n 
1 792 HIS n 
1 793 ALA n 
1 794 ASN n 
1 795 THR n 
1 796 PRO n 
1 797 GLU n 
1 798 THR n 
1 799 GLN n 
1 800 THR n 
1 801 LEU n 
1 802 PHE n 
1 803 GLN n 
1 804 SER n 
1 805 GLY n 
1 806 TRP n 
1 807 PHE n 
1 808 VAL n 
1 809 VAL n 
1 810 GLY n 
1 811 LEU n 
1 812 LEU n 
1 813 SER n 
1 814 GLN n 
1 815 THR n 
1 816 LEU n 
1 817 ILE n 
1 818 VAL n 
1 819 HIS n 
1 820 MET n 
1 821 ILE n 
1 822 ARG n 
1 823 THR n 
1 824 ARG n 
1 825 ARG n 
1 826 VAL n 
1 827 PRO n 
1 828 PHE n 
1 829 ILE n 
1 830 GLN n 
1 831 SER n 
1 832 CYS n 
1 833 ALA n 
1 834 SER n 
1 835 TRP n 
1 836 PRO n 
1 837 LEU n 
1 838 MET n 
1 839 ILE n 
1 840 MET n 
1 841 THR n 
1 842 VAL n 
1 843 ILE n 
1 844 VAL n 
1 845 MET n 
1 846 ILE n 
1 847 VAL n 
1 848 GLY n 
1 849 ILE n 
1 850 ALA n 
1 851 LEU n 
1 852 PRO n 
1 853 PHE n 
1 854 SER n 
1 855 PRO n 
1 856 LEU n 
1 857 ALA n 
1 858 SER n 
1 859 TYR n 
1 860 LEU n 
1 861 GLN n 
1 862 LEU n 
1 863 GLN n 
1 864 ALA n 
1 865 LEU n 
1 866 PRO n 
1 867 LEU n 
1 868 SER n 
1 869 TYR n 
1 870 PHE n 
1 871 PRO n 
1 872 TRP n 
1 873 LEU n 
1 874 VAL n 
1 875 ALA n 
1 876 ILE n 
1 877 LEU n 
1 878 ALA n 
1 879 GLY n 
1 880 TYR n 
1 881 MET n 
1 882 THR n 
1 883 LEU n 
1 884 THR n 
1 885 GLN n 
1 886 LEU n 
1 887 VAL n 
1 888 LYS n 
1 889 GLY n 
1 890 PHE n 
1 891 TYR n 
1 892 SER n 
1 893 ARG n 
1 894 ARG n 
1 895 TYR n 
1 896 GLY n 
1 897 TRP n 
1 898 GLN n 
1 899 HIS n 
1 900 HIS n 
1 901 HIS n 
1 902 HIS n 
1 903 HIS n 
1 904 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   904 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 mgtA 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    'Escherichia coli K-12' 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     83333 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'Escherichia coli C43 (DE3)' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          'Bacterial expression, coexpression' 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   
;pETDuet-1 is designed for the coexpression of two target genes. pETDuet-1 carries the pBR322-derived ColE1 replicon, the lacI gene and the ampicillin resistance gene.
;
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pETDuet-1 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
MG  non-polymer         . 'MAGNESIUM ION' ? 'Mg 2'           24.305  
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   PHE 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   ?   ?   ?   A . n 
A 1 4   GLU 4   4   ?   ?   ?   A . n 
A 1 5   ILE 5   5   ?   ?   ?   A . n 
A 1 6   PHE 6   6   ?   ?   ?   A . n 
A 1 7   THR 7   7   ?   ?   ?   A . n 
A 1 8   ARG 8   8   ?   ?   ?   A . n 
A 1 9   LEU 9   9   ?   ?   ?   A . n 
A 1 10  ILE 10  10  ?   ?   ?   A . n 
A 1 11  ARG 11  11  ?   ?   ?   A . n 
A 1 12  HIS 12  12  ?   ?   ?   A . n 
A 1 13  LEU 13  13  ?   ?   ?   A . n 
A 1 14  PRO 14  14  ?   ?   ?   A . n 
A 1 15  SER 15  15  ?   ?   ?   A . n 
A 1 16  ARG 16  16  ?   ?   ?   A . n 
A 1 17  LEU 17  17  ?   ?   ?   A . n 
A 1 18  VAL 18  18  ?   ?   ?   A . n 
A 1 19  HIS 19  19  ?   ?   ?   A . n 
A 1 20  ARG 20  20  ?   ?   ?   A . n 
A 1 21  ASP 21  21  ?   ?   ?   A . n 
A 1 22  PRO 22  22  ?   ?   ?   A . n 
A 1 23  LEU 23  23  ?   ?   ?   A . n 
A 1 24  PRO 24  24  ?   ?   ?   A . n 
A 1 25  GLY 25  25  ?   ?   ?   A . n 
A 1 26  ALA 26  26  ?   ?   ?   A . n 
A 1 27  GLN 27  27  ?   ?   ?   A . n 
A 1 28  GLN 28  28  ?   ?   ?   A . n 
A 1 29  THR 29  29  ?   ?   ?   A . n 
A 1 30  VAL 30  30  ?   ?   ?   A . n 
A 1 31  ASN 31  31  ?   ?   ?   A . n 
A 1 32  THR 32  32  ?   ?   ?   A . n 
A 1 33  VAL 33  33  ?   ?   ?   A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  PRO 35  35  35  PRO PRO A . n 
A 1 36  PRO 36  36  36  PRO PRO A . n 
A 1 37  SER 37  37  37  SER SER A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  CYS 42  42  42  CYS CYS A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  LYS 44  44  44  LYS LYS A . n 
A 1 45  MET 45  45  45  MET MET A . n 
A 1 46  ALA 46  46  46  ALA ALA A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  MET 48  48  48  MET MET A . n 
A 1 49  PRO 49  49  49  PRO PRO A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  GLU 51  51  51  GLU GLU A . n 
A 1 52  GLU 52  52  52  GLU GLU A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  TRP 54  54  54  TRP TRP A . n 
A 1 55  LYS 55  55  55  LYS LYS A . n 
A 1 56  THR 56  56  56  THR THR A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  HIS 60  60  60  HIS HIS A . n 
A 1 61  PRO 61  61  61  PRO PRO A . n 
A 1 62  GLU 62  62  62  GLU GLU A . n 
A 1 63  GLY 63  63  63  GLY GLY A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  GLN 66  66  66  GLN GLN A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  GLU 68  68  68  GLU GLU A . n 
A 1 69  VAL 69  69  69  VAL VAL A . n 
A 1 70  GLU 70  70  70  GLU GLU A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  ARG 73  73  73  ARG ARG A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  GLN 75  75  75  GLN GLN A . n 
A 1 76  HIS 76  76  76  HIS HIS A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  LYS 80  80  80  LYS LYS A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  GLN 84  84  84  GLN GLN A . n 
A 1 85  GLN 85  85  85  GLN GLN A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  SER 87  87  87  SER SER A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  TRP 89  89  89  TRP TRP A . n 
A 1 90  TRP 90  90  90  TRP TRP A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  HIS 92  92  92  HIS HIS A . n 
A 1 93  LEU 93  93  93  LEU LEU A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  VAL 95  95  95  VAL VAL A . n 
A 1 96  CYS 96  96  96  CYS CYS A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  ARG 98  98  98  ARG ARG A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 PRO 100 100 100 PRO PRO A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 ASN 102 102 102 ASN ASN A . n 
A 1 103 ILE 103 103 103 ILE ILE A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 THR 106 106 106 THR THR A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 LEU 108 108 108 LEU LEU A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 ALA 110 110 110 ALA ALA A . n 
A 1 111 ILE 111 111 111 ILE ILE A . n 
A 1 112 SER 112 112 112 SER SER A . n 
A 1 113 TYR 113 113 113 TYR TYR A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 THR 115 115 115 THR THR A . n 
A 1 116 GLU 116 116 116 GLU GLU A . n 
A 1 117 ASP 117 117 117 ASP ASP A . n 
A 1 118 LEU 118 118 118 LEU LEU A . n 
A 1 119 PHE 119 119 119 PHE PHE A . n 
A 1 120 ALA 120 120 120 ALA ALA A . n 
A 1 121 ALA 121 121 121 ALA ALA A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 VAL 123 123 123 VAL VAL A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 LEU 126 126 126 LEU LEU A . n 
A 1 127 MET 127 127 127 MET MET A . n 
A 1 128 VAL 128 128 128 VAL VAL A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 ILE 130 130 130 ILE ILE A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 PHE 136 136 136 PHE PHE A . n 
A 1 137 ILE 137 137 137 ILE ILE A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 ARG 141 141 141 ARG ARG A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 ASP 147 147 147 ASP ASP A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 LYS 150 150 150 LYS LYS A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 MET 152 152 152 MET MET A . n 
A 1 153 VAL 153 153 153 VAL VAL A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 ASN 155 155 155 ASN ASN A . n 
A 1 156 THR 156 156 156 THR THR A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ARG 161 161 161 ARG ARG A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 ASN 164 164 164 ASN ASN A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 LYS 166 166 166 LYS LYS A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 GLU 168 168 168 GLU GLU A . n 
A 1 169 ASN 169 169 169 ASN ASN A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 TRP 171 171 171 TRP TRP A . n 
A 1 172 LEU 172 172 172 LEU LEU A . n 
A 1 173 GLU 173 173 173 GLU GLU A . n 
A 1 174 ILE 174 174 174 ILE ILE A . n 
A 1 175 PRO 175 175 175 PRO PRO A . n 
A 1 176 ILE 176 176 176 ILE ILE A . n 
A 1 177 ASP 177 177 177 ASP ASP A . n 
A 1 178 GLN 178 178 178 GLN GLN A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 PRO 181 181 181 PRO PRO A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 ASP 183 183 183 ASP ASP A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 ILE 185 185 185 ILE ILE A . n 
A 1 186 LYS 186 186 186 LYS LYS A . n 
A 1 187 LEU 187 187 187 LEU LEU A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 ALA 189 189 189 ALA ALA A . n 
A 1 190 GLY 190 190 190 GLY GLY A . n 
A 1 191 ASP 191 191 191 ASP ASP A . n 
A 1 192 MET 192 192 192 MET MET A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 PRO 194 194 194 PRO PRO A . n 
A 1 195 ALA 195 195 195 ALA ALA A . n 
A 1 196 ASP 196 196 196 ASP ASP A . n 
A 1 197 LEU 197 197 197 LEU LEU A . n 
A 1 198 ARG 198 198 198 ARG ARG A . n 
A 1 199 ILE 199 199 199 ILE ILE A . n 
A 1 200 LEU 200 200 200 LEU LEU A . n 
A 1 201 GLN 201 201 201 GLN GLN A . n 
A 1 202 ALA 202 202 202 ALA ALA A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 ASP 204 204 204 ASP ASP A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 PHE 206 206 206 PHE PHE A . n 
A 1 207 VAL 207 207 207 VAL VAL A . n 
A 1 208 ALA 208 208 208 ALA ALA A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 SER 211 211 211 SER SER A . n 
A 1 212 LEU 212 212 212 LEU LEU A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 GLY 214 214 214 GLY GLY A . n 
A 1 215 GLU 215 215 215 GLU GLU A . n 
A 1 216 SER 216 216 216 SER SER A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 VAL 219 219 219 VAL VAL A . n 
A 1 220 GLU 220 220 220 GLU GLU A . n 
A 1 221 LYS 221 221 221 LYS LYS A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 ALA 223 223 223 ALA ALA A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 ARG 226 226 226 ARG ARG A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 GLU 229 229 229 GLU GLU A . n 
A 1 230 HIS 230 230 230 HIS HIS A . n 
A 1 231 SER 231 231 231 SER SER A . n 
A 1 232 ASN 232 232 232 ASN ASN A . n 
A 1 233 PRO 233 233 233 PRO PRO A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 GLU 235 235 235 GLU GLU A . n 
A 1 236 CYS 236 236 236 CYS CYS A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 THR 238 238 238 THR THR A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 CYS 240 240 240 CYS CYS A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 MET 242 242 242 MET MET A . n 
A 1 243 GLY 243 243 243 GLY GLY A . n 
A 1 244 THR 244 244 244 THR THR A . n 
A 1 245 THR 245 245 245 THR THR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 SER 248 248 248 SER SER A . n 
A 1 249 GLY 249 249 249 GLY GLY A . n 
A 1 250 THR 250 250 250 THR THR A . n 
A 1 251 ALA 251 251 251 ALA ALA A . n 
A 1 252 GLN 252 252 252 GLN GLN A . n 
A 1 253 ALA 253 253 253 ALA ALA A . n 
A 1 254 MET 254 254 254 MET MET A . n 
A 1 255 VAL 255 255 255 VAL VAL A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 ASN 261 261 261 ASN ASN A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 TRP 263 263 263 TRP TRP A . n 
A 1 264 PHE 264 264 264 PHE PHE A . n 
A 1 265 GLY 265 265 265 GLY GLY A . n 
A 1 266 GLN 266 266 266 GLN GLN A . n 
A 1 267 LEU 267 267 267 LEU LEU A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 ARG 270 270 270 ARG ARG A . n 
A 1 271 VAL 271 271 271 VAL VAL A . n 
A 1 272 SER 272 272 272 SER SER A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 GLN 274 274 274 GLN GLN A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 GLU 277 277 277 GLU GLU A . n 
A 1 278 PRO 278 278 278 PRO PRO A . n 
A 1 279 ASN 279 279 279 ASN ASN A . n 
A 1 280 ALA 280 280 280 ALA ALA A . n 
A 1 281 PHE 281 281 281 PHE PHE A . n 
A 1 282 GLN 282 282 282 GLN GLN A . n 
A 1 283 GLN 283 283 283 GLN GLN A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 SER 286 286 286 SER SER A . n 
A 1 287 ARG 287 287 287 ARG ARG A . n 
A 1 288 VAL 288 288 288 VAL VAL A . n 
A 1 289 SER 289 289 289 SER SER A . n 
A 1 290 MET 290 290 290 MET MET A . n 
A 1 291 LEU 291 291 291 LEU LEU A . n 
A 1 292 LEU 292 292 292 LEU LEU A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 ARG 294 294 294 ARG ARG A . n 
A 1 295 PHE 295 295 295 PHE PHE A . n 
A 1 296 MET 296 296 296 MET MET A . n 
A 1 297 LEU 297 297 297 LEU LEU A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 MET 299 299 299 MET MET A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 PRO 301 301 301 PRO PRO A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 LEU 304 304 304 LEU LEU A . n 
A 1 305 LEU 305 305 305 LEU LEU A . n 
A 1 306 ILE 306 306 306 ILE ILE A . n 
A 1 307 ASN 307 307 307 ASN ASN A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 TYR 309 309 309 TYR TYR A . n 
A 1 310 THR 310 310 310 THR THR A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 GLY 312 312 312 GLY GLY A . n 
A 1 313 ASP 313 313 313 ASP ASP A . n 
A 1 314 TRP 314 314 314 TRP TRP A . n 
A 1 315 TRP 315 315 315 TRP TRP A . n 
A 1 316 GLU 316 316 316 GLU GLU A . n 
A 1 317 ALA 317 317 317 ALA ALA A . n 
A 1 318 ALA 318 318 318 ALA ALA A . n 
A 1 319 LEU 319 319 319 LEU LEU A . n 
A 1 320 PHE 320 320 320 PHE PHE A . n 
A 1 321 ALA 321 321 321 ALA ALA A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 SER 323 323 323 SER SER A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 VAL 326 326 326 VAL VAL A . n 
A 1 327 GLY 327 327 327 GLY GLY A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 PRO 330 330 330 PRO PRO A . n 
A 1 331 GLU 331 331 331 GLU GLU A . n 
A 1 332 MET 332 332 332 MET MET A . n 
A 1 333 LEU 333 333 333 LEU LEU A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 MET 335 335 335 MET MET A . n 
A 1 336 ILE 336 336 336 ILE ILE A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 THR 338 338 338 THR THR A . n 
A 1 339 SER 339 339 339 SER SER A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 ARG 343 343 343 ARG ARG A . n 
A 1 344 GLY 344 344 344 GLY GLY A . n 
A 1 345 ALA 345 345 345 ALA ALA A . n 
A 1 346 VAL 346 346 346 VAL VAL A . n 
A 1 347 LYS 347 347 347 LYS LYS A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 SER 349 349 349 SER SER A . n 
A 1 350 LYS 350 350 350 LYS LYS A . n 
A 1 351 GLN 351 351 351 GLN GLN A . n 
A 1 352 LYS 352 352 352 LYS LYS A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 ILE 354 354 354 ILE ILE A . n 
A 1 355 VAL 355 355 355 VAL VAL A . n 
A 1 356 LYS 356 356 356 LYS LYS A . n 
A 1 357 HIS 357 357 357 HIS HIS A . n 
A 1 358 LEU 358 358 358 LEU LEU A . n 
A 1 359 ASP 359 359 359 ASP ASP A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ILE 361 361 361 ILE ILE A . n 
A 1 362 GLN 362 362 362 GLN GLN A . n 
A 1 363 ASN 363 363 363 ASN ASN A . n 
A 1 364 PHE 364 364 364 PHE PHE A . n 
A 1 365 GLY 365 365 365 GLY GLY A . n 
A 1 366 ALA 366 366 366 ALA ALA A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 ASP 368 368 368 ASP ASP A . n 
A 1 369 ILE 369 369 369 ILE ILE A . n 
A 1 370 LEU 370 370 370 LEU LEU A . n 
A 1 371 CYS 371 371 371 CYS CYS A . n 
A 1 372 THR 372 372 372 THR THR A . n 
A 1 373 ASP 373 373 373 ASP ASP A . n 
A 1 374 LYS 374 374 374 LYS LYS A . n 
A 1 375 THR 375 375 375 THR THR A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 THR 377 377 377 THR THR A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 THR 379 379 379 THR THR A . n 
A 1 380 GLN 380 380 380 GLN GLN A . n 
A 1 381 ASP 381 381 381 ASP ASP A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 LEU 385 385 385 LEU LEU A . n 
A 1 386 GLU 386 386 386 GLU GLU A . n 
A 1 387 ASN 387 387 387 ASN ASN A . n 
A 1 388 HIS 388 388 388 HIS HIS A . n 
A 1 389 THR 389 389 389 THR THR A . n 
A 1 390 ASP 390 390 390 ASP ASP A . n 
A 1 391 ILE 391 391 391 ILE ILE A . n 
A 1 392 SER 392 392 392 SER SER A . n 
A 1 393 GLY 393 393 393 GLY GLY A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 THR 395 395 395 THR THR A . n 
A 1 396 SER 396 396 396 SER SER A . n 
A 1 397 GLU 397 397 397 GLU GLU A . n 
A 1 398 ARG 398 398 398 ARG ARG A . n 
A 1 399 VAL 399 399 399 VAL VAL A . n 
A 1 400 LEU 400 400 400 LEU LEU A . n 
A 1 401 HIS 401 401 401 HIS HIS A . n 
A 1 402 SER 402 402 402 SER SER A . n 
A 1 403 ALA 403 403 403 ALA ALA A . n 
A 1 404 TRP 404 404 404 TRP TRP A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 ASN 406 406 406 ASN ASN A . n 
A 1 407 SER 407 407 407 SER SER A . n 
A 1 408 HIS 408 408 408 HIS HIS A . n 
A 1 409 TYR 409 409 409 TYR TYR A . n 
A 1 410 GLN 410 410 410 GLN GLN A . n 
A 1 411 THR 411 411 411 THR THR A . n 
A 1 412 GLY 412 412 412 GLY GLY A . n 
A 1 413 LEU 413 413 413 LEU LEU A . n 
A 1 414 LYS 414 414 414 LYS LYS A . n 
A 1 415 ASN 415 415 415 ASN ASN A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 LEU 417 417 417 LEU LEU A . n 
A 1 418 ASP 418 418 418 ASP ASP A . n 
A 1 419 THR 419 419 419 THR THR A . n 
A 1 420 ALA 420 420 420 ALA ALA A . n 
A 1 421 VAL 421 421 421 VAL VAL A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 GLU 423 423 423 GLU GLU A . n 
A 1 424 GLY 424 424 424 GLY GLY A . n 
A 1 425 THR 425 425 425 THR THR A . n 
A 1 426 ASP 426 426 426 ASP ASP A . n 
A 1 427 GLU 427 427 427 GLU GLU A . n 
A 1 428 GLU 428 428 428 GLU GLU A . n 
A 1 429 SER 429 429 429 SER SER A . n 
A 1 430 ALA 430 430 430 ALA ALA A . n 
A 1 431 ARG 431 431 431 ARG ARG A . n 
A 1 432 SER 432 432 432 SER SER A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 SER 435 435 435 SER SER A . n 
A 1 436 ARG 436 436 436 ARG ARG A . n 
A 1 437 TRP 437 437 437 TRP TRP A . n 
A 1 438 GLN 438 438 438 GLN GLN A . n 
A 1 439 LYS 439 439 439 LYS LYS A . n 
A 1 440 ILE 440 440 440 ILE ILE A . n 
A 1 441 ASP 441 441 441 ASP ASP A . n 
A 1 442 GLU 442 442 442 GLU GLU A . n 
A 1 443 ILE 443 443 443 ILE ILE A . n 
A 1 444 PRO 444 444 444 PRO PRO A . n 
A 1 445 PHE 445 445 445 PHE PHE A . n 
A 1 446 ASP 446 446 446 ASP ASP A . n 
A 1 447 PHE 447 447 447 PHE PHE A . n 
A 1 448 GLU 448 448 448 GLU GLU A . n 
A 1 449 ARG 449 449 449 ARG ARG A . n 
A 1 450 ARG 450 450 450 ARG ARG A . n 
A 1 451 ARG 451 451 451 ARG ARG A . n 
A 1 452 MET 452 452 452 MET MET A . n 
A 1 453 SER 453 453 453 SER SER A . n 
A 1 454 VAL 454 454 454 VAL VAL A . n 
A 1 455 VAL 455 455 455 VAL VAL A . n 
A 1 456 VAL 456 456 456 VAL VAL A . n 
A 1 457 ALA 457 457 457 ALA ALA A . n 
A 1 458 GLU 458 458 458 GLU GLU A . n 
A 1 459 ASN 459 459 459 ASN ASN A . n 
A 1 460 THR 460 460 460 THR THR A . n 
A 1 461 GLU 461 461 461 GLU GLU A . n 
A 1 462 HIS 462 462 462 HIS HIS A . n 
A 1 463 HIS 463 463 463 HIS HIS A . n 
A 1 464 GLN 464 464 464 GLN GLN A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 CYS 467 467 467 CYS CYS A . n 
A 1 468 LYS 468 468 468 LYS LYS A . n 
A 1 469 GLY 469 469 469 GLY GLY A . n 
A 1 470 ALA 470 470 470 ALA ALA A . n 
A 1 471 LEU 471 471 471 LEU LEU A . n 
A 1 472 GLN 472 472 472 GLN GLN A . n 
A 1 473 GLU 473 473 473 GLU GLU A . n 
A 1 474 ILE 474 474 474 ILE ILE A . n 
A 1 475 LEU 475 475 475 LEU LEU A . n 
A 1 476 ASN 476 476 476 ASN ASN A . n 
A 1 477 VAL 477 477 477 VAL VAL A . n 
A 1 478 CYS 478 478 478 CYS CYS A . n 
A 1 479 SER 479 479 479 SER SER A . n 
A 1 480 GLN 480 480 480 GLN GLN A . n 
A 1 481 VAL 481 481 481 VAL VAL A . n 
A 1 482 ARG 482 482 482 ARG ARG A . n 
A 1 483 HIS 483 483 483 HIS HIS A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 GLY 485 485 485 GLY GLY A . n 
A 1 486 GLU 486 486 486 GLU GLU A . n 
A 1 487 ILE 487 487 487 ILE ILE A . n 
A 1 488 VAL 488 488 488 VAL VAL A . n 
A 1 489 PRO 489 489 489 PRO PRO A . n 
A 1 490 LEU 490 490 490 LEU LEU A . n 
A 1 491 ASP 491 491 491 ASP ASP A . n 
A 1 492 ASP 492 492 492 ASP ASP A . n 
A 1 493 ILE 493 493 493 ILE ILE A . n 
A 1 494 MET 494 494 494 MET MET A . n 
A 1 495 LEU 495 495 495 LEU LEU A . n 
A 1 496 ARG 496 496 496 ARG ARG A . n 
A 1 497 LYS 497 497 497 LYS LYS A . n 
A 1 498 ILE 498 498 498 ILE ILE A . n 
A 1 499 LYS 499 499 499 LYS LYS A . n 
A 1 500 ARG 500 500 500 ARG ARG A . n 
A 1 501 VAL 501 501 501 VAL VAL A . n 
A 1 502 THR 502 502 502 THR THR A . n 
A 1 503 ASP 503 503 503 ASP ASP A . n 
A 1 504 THR 504 504 504 THR THR A . n 
A 1 505 LEU 505 505 505 LEU LEU A . n 
A 1 506 ASN 506 506 506 ASN ASN A . n 
A 1 507 ARG 507 507 507 ARG ARG A . n 
A 1 508 GLN 508 508 508 GLN GLN A . n 
A 1 509 GLY 509 509 509 GLY GLY A . n 
A 1 510 LEU 510 510 510 LEU LEU A . n 
A 1 511 ARG 511 511 511 ARG ARG A . n 
A 1 512 VAL 512 512 512 VAL VAL A . n 
A 1 513 VAL 513 513 513 VAL VAL A . n 
A 1 514 ALA 514 514 514 ALA ALA A . n 
A 1 515 VAL 515 515 515 VAL VAL A . n 
A 1 516 ALA 516 516 516 ALA ALA A . n 
A 1 517 THR 517 517 517 THR THR A . n 
A 1 518 LYS 518 518 518 LYS LYS A . n 
A 1 519 TYR 519 519 519 TYR TYR A . n 
A 1 520 LEU 520 520 520 LEU LEU A . n 
A 1 521 PRO 521 521 521 PRO PRO A . n 
A 1 522 ALA 522 522 522 ALA ALA A . n 
A 1 523 ARG 523 523 523 ARG ARG A . n 
A 1 524 GLU 524 524 524 GLU GLU A . n 
A 1 525 GLY 525 525 525 GLY GLY A . n 
A 1 526 ASP 526 526 526 ASP ASP A . n 
A 1 527 TYR 527 527 527 TYR TYR A . n 
A 1 528 GLN 528 528 528 GLN GLN A . n 
A 1 529 ARG 529 529 529 ARG ARG A . n 
A 1 530 ALA 530 530 530 ALA ALA A . n 
A 1 531 ASP 531 531 531 ASP ASP A . n 
A 1 532 GLU 532 532 532 GLU GLU A . n 
A 1 533 SER 533 533 533 SER SER A . n 
A 1 534 ASP 534 534 534 ASP ASP A . n 
A 1 535 LEU 535 535 535 LEU LEU A . n 
A 1 536 ILE 536 536 536 ILE ILE A . n 
A 1 537 LEU 537 537 537 LEU LEU A . n 
A 1 538 GLU 538 538 538 GLU GLU A . n 
A 1 539 GLY 539 539 539 GLY GLY A . n 
A 1 540 TYR 540 540 540 TYR TYR A . n 
A 1 541 ILE 541 541 541 ILE ILE A . n 
A 1 542 ALA 542 542 542 ALA ALA A . n 
A 1 543 PHE 543 543 543 PHE PHE A . n 
A 1 544 LEU 544 544 544 LEU LEU A . n 
A 1 545 ASP 545 545 545 ASP ASP A . n 
A 1 546 PRO 546 546 546 PRO PRO A . n 
A 1 547 PRO 547 547 547 PRO PRO A . n 
A 1 548 LYS 548 548 548 LYS LYS A . n 
A 1 549 GLU 549 549 549 GLU GLU A . n 
A 1 550 THR 550 550 550 THR THR A . n 
A 1 551 THR 551 551 551 THR THR A . n 
A 1 552 ALA 552 552 552 ALA ALA A . n 
A 1 553 PRO 553 553 553 PRO PRO A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 LEU 555 555 555 LEU LEU A . n 
A 1 556 LYS 556 556 556 LYS LYS A . n 
A 1 557 ALA 557 557 557 ALA ALA A . n 
A 1 558 LEU 558 558 558 LEU LEU A . n 
A 1 559 LYS 559 559 559 LYS LYS A . n 
A 1 560 ALA 560 560 560 ALA ALA A . n 
A 1 561 SER 561 561 561 SER SER A . n 
A 1 562 GLY 562 562 562 GLY GLY A . n 
A 1 563 ILE 563 563 563 ILE ILE A . n 
A 1 564 THR 564 564 564 THR THR A . n 
A 1 565 VAL 565 565 565 VAL VAL A . n 
A 1 566 LYS 566 566 566 LYS LYS A . n 
A 1 567 ILE 567 567 567 ILE ILE A . n 
A 1 568 LEU 568 568 568 LEU LEU A . n 
A 1 569 THR 569 569 569 THR THR A . n 
A 1 570 GLY 570 570 570 GLY GLY A . n 
A 1 571 ASP 571 571 571 ASP ASP A . n 
A 1 572 SER 572 572 572 SER SER A . n 
A 1 573 GLU 573 573 573 GLU GLU A . n 
A 1 574 LEU 574 574 574 LEU LEU A . n 
A 1 575 VAL 575 575 575 VAL VAL A . n 
A 1 576 ALA 576 576 576 ALA ALA A . n 
A 1 577 ALA 577 577 577 ALA ALA A . n 
A 1 578 LYS 578 578 578 LYS LYS A . n 
A 1 579 VAL 579 579 579 VAL VAL A . n 
A 1 580 CYS 580 580 580 CYS CYS A . n 
A 1 581 HIS 581 581 581 HIS HIS A . n 
A 1 582 GLU 582 582 582 GLU GLU A . n 
A 1 583 VAL 583 583 583 VAL VAL A . n 
A 1 584 GLY 584 584 584 GLY GLY A . n 
A 1 585 LEU 585 585 585 LEU LEU A . n 
A 1 586 ASP 586 586 586 ASP ASP A . n 
A 1 587 ALA 587 587 587 ALA ALA A . n 
A 1 588 GLY 588 588 588 GLY GLY A . n 
A 1 589 GLU 589 589 589 GLU GLU A . n 
A 1 590 VAL 590 590 590 VAL VAL A . n 
A 1 591 VAL 591 591 591 VAL VAL A . n 
A 1 592 ILE 592 592 592 ILE ILE A . n 
A 1 593 GLY 593 593 593 GLY GLY A . n 
A 1 594 SER 594 594 594 SER SER A . n 
A 1 595 ASP 595 595 595 ASP ASP A . n 
A 1 596 ILE 596 596 596 ILE ILE A . n 
A 1 597 GLU 597 597 597 GLU GLU A . n 
A 1 598 THR 598 598 598 THR THR A . n 
A 1 599 LEU 599 599 599 LEU LEU A . n 
A 1 600 SER 600 600 600 SER SER A . n 
A 1 601 ASP 601 601 601 ASP ASP A . n 
A 1 602 ASP 602 602 602 ASP ASP A . n 
A 1 603 GLU 603 603 603 GLU GLU A . n 
A 1 604 LEU 604 604 604 LEU LEU A . n 
A 1 605 ALA 605 605 605 ALA ALA A . n 
A 1 606 ASN 606 606 606 ASN ASN A . n 
A 1 607 LEU 607 607 607 LEU LEU A . n 
A 1 608 ALA 608 608 608 ALA ALA A . n 
A 1 609 GLN 609 609 609 GLN GLN A . n 
A 1 610 ARG 610 610 610 ARG ARG A . n 
A 1 611 THR 611 611 611 THR THR A . n 
A 1 612 THR 612 612 612 THR THR A . n 
A 1 613 LEU 613 613 613 LEU LEU A . n 
A 1 614 PHE 614 614 614 PHE PHE A . n 
A 1 615 ALA 615 615 615 ALA ALA A . n 
A 1 616 ARG 616 616 616 ARG ARG A . n 
A 1 617 LEU 617 617 617 LEU LEU A . n 
A 1 618 THR 618 618 618 THR THR A . n 
A 1 619 PRO 619 619 619 PRO PRO A . n 
A 1 620 MET 620 620 620 MET MET A . n 
A 1 621 HIS 621 621 621 HIS HIS A . n 
A 1 622 LYS 622 622 622 LYS LYS A . n 
A 1 623 GLU 623 623 623 GLU GLU A . n 
A 1 624 ARG 624 624 624 ARG ARG A . n 
A 1 625 ILE 625 625 625 ILE ILE A . n 
A 1 626 VAL 626 626 626 VAL VAL A . n 
A 1 627 THR 627 627 627 THR THR A . n 
A 1 628 LEU 628 628 628 LEU LEU A . n 
A 1 629 LEU 629 629 629 LEU LEU A . n 
A 1 630 LYS 630 630 630 LYS LYS A . n 
A 1 631 ARG 631 631 631 ARG ARG A . n 
A 1 632 GLU 632 632 632 GLU GLU A . n 
A 1 633 GLY 633 633 633 GLY GLY A . n 
A 1 634 HIS 634 634 634 HIS HIS A . n 
A 1 635 VAL 635 635 635 VAL VAL A . n 
A 1 636 VAL 636 636 636 VAL VAL A . n 
A 1 637 GLY 637 637 637 GLY GLY A . n 
A 1 638 PHE 638 638 638 PHE PHE A . n 
A 1 639 MET 639 639 639 MET MET A . n 
A 1 640 GLY 640 640 640 GLY GLY A . n 
A 1 641 ASP 641 641 641 ASP ASP A . n 
A 1 642 GLY 642 642 642 GLY GLY A . n 
A 1 643 ILE 643 643 643 ILE ILE A . n 
A 1 644 ASN 644 644 644 ASN ASN A . n 
A 1 645 ASP 645 645 645 ASP ASP A . n 
A 1 646 ALA 646 646 646 ALA ALA A . n 
A 1 647 PRO 647 647 647 PRO PRO A . n 
A 1 648 ALA 648 648 648 ALA ALA A . n 
A 1 649 LEU 649 649 649 LEU LEU A . n 
A 1 650 ARG 650 650 650 ARG ARG A . n 
A 1 651 ALA 651 651 651 ALA ALA A . n 
A 1 652 ALA 652 652 652 ALA ALA A . n 
A 1 653 ASP 653 653 653 ASP ASP A . n 
A 1 654 ILE 654 654 654 ILE ILE A . n 
A 1 655 GLY 655 655 655 GLY GLY A . n 
A 1 656 ILE 656 656 656 ILE ILE A . n 
A 1 657 SER 657 657 657 SER SER A . n 
A 1 658 VAL 658 658 658 VAL VAL A . n 
A 1 659 ASP 659 659 659 ASP ASP A . n 
A 1 660 GLY 660 660 660 GLY GLY A . n 
A 1 661 ALA 661 661 661 ALA ALA A . n 
A 1 662 VAL 662 662 662 VAL VAL A . n 
A 1 663 ASP 663 663 663 ASP ASP A . n 
A 1 664 ILE 664 664 664 ILE ILE A . n 
A 1 665 ALA 665 665 665 ALA ALA A . n 
A 1 666 ARG 666 666 666 ARG ARG A . n 
A 1 667 GLU 667 667 667 GLU GLU A . n 
A 1 668 ALA 668 668 668 ALA ALA A . n 
A 1 669 ALA 669 669 669 ALA ALA A . n 
A 1 670 ASP 670 670 670 ASP ASP A . n 
A 1 671 ILE 671 671 671 ILE ILE A . n 
A 1 672 ILE 672 672 672 ILE ILE A . n 
A 1 673 LEU 673 673 673 LEU LEU A . n 
A 1 674 LEU 674 674 674 LEU LEU A . n 
A 1 675 GLU 675 675 675 GLU GLU A . n 
A 1 676 LYS 676 676 676 LYS LYS A . n 
A 1 677 SER 677 677 677 SER SER A . n 
A 1 678 LEU 678 678 678 LEU LEU A . n 
A 1 679 MET 679 679 679 MET MET A . n 
A 1 680 VAL 680 680 680 VAL VAL A . n 
A 1 681 LEU 681 681 681 LEU LEU A . n 
A 1 682 GLU 682 682 682 GLU GLU A . n 
A 1 683 GLU 683 683 683 GLU GLU A . n 
A 1 684 GLY 684 684 684 GLY GLY A . n 
A 1 685 VAL 685 685 685 VAL VAL A . n 
A 1 686 ILE 686 686 686 ILE ILE A . n 
A 1 687 GLU 687 687 687 GLU GLU A . n 
A 1 688 GLY 688 688 688 GLY GLY A . n 
A 1 689 ARG 689 689 689 ARG ARG A . n 
A 1 690 ARG 690 690 690 ARG ARG A . n 
A 1 691 THR 691 691 691 THR THR A . n 
A 1 692 PHE 692 692 692 PHE PHE A . n 
A 1 693 ALA 693 693 693 ALA ALA A . n 
A 1 694 ASN 694 694 694 ASN ASN A . n 
A 1 695 MET 695 695 695 MET MET A . n 
A 1 696 LEU 696 696 696 LEU LEU A . n 
A 1 697 LYS 697 697 697 LYS LYS A . n 
A 1 698 TYR 698 698 698 TYR TYR A . n 
A 1 699 ILE 699 699 699 ILE ILE A . n 
A 1 700 LYS 700 700 700 LYS LYS A . n 
A 1 701 MET 701 701 701 MET MET A . n 
A 1 702 THR 702 702 702 THR THR A . n 
A 1 703 ALA 703 703 703 ALA ALA A . n 
A 1 704 SER 704 704 704 SER SER A . n 
A 1 705 SER 705 705 705 SER SER A . n 
A 1 706 ASN 706 706 706 ASN ASN A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 GLY 708 708 708 GLY GLY A . n 
A 1 709 ASN 709 709 709 ASN ASN A . n 
A 1 710 VAL 710 710 710 VAL VAL A . n 
A 1 711 PHE 711 711 711 PHE PHE A . n 
A 1 712 SER 712 712 712 SER SER A . n 
A 1 713 VAL 713 713 713 VAL VAL A . n 
A 1 714 LEU 714 714 714 LEU LEU A . n 
A 1 715 VAL 715 715 715 VAL VAL A . n 
A 1 716 ALA 716 716 716 ALA ALA A . n 
A 1 717 SER 717 717 717 SER SER A . n 
A 1 718 ALA 718 718 718 ALA ALA A . n 
A 1 719 PHE 719 719 719 PHE PHE A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 PRO 721 721 721 PRO PRO A . n 
A 1 722 PHE 722 722 722 PHE PHE A . n 
A 1 723 LEU 723 723 723 LEU LEU A . n 
A 1 724 PRO 724 724 724 PRO PRO A . n 
A 1 725 MET 725 725 725 MET MET A . n 
A 1 726 LEU 726 726 726 LEU LEU A . n 
A 1 727 PRO 727 727 727 PRO PRO A . n 
A 1 728 LEU 728 728 728 LEU LEU A . n 
A 1 729 HIS 729 729 729 HIS HIS A . n 
A 1 730 LEU 730 730 730 LEU LEU A . n 
A 1 731 LEU 731 731 731 LEU LEU A . n 
A 1 732 ILE 732 732 732 ILE ILE A . n 
A 1 733 GLN 733 733 733 GLN GLN A . n 
A 1 734 ASN 734 734 734 ASN ASN A . n 
A 1 735 LEU 735 735 735 LEU LEU A . n 
A 1 736 LEU 736 736 736 LEU LEU A . n 
A 1 737 TYR 737 737 737 TYR TYR A . n 
A 1 738 ASP 738 738 738 ASP ASP A . n 
A 1 739 VAL 739 739 739 VAL VAL A . n 
A 1 740 SER 740 740 740 SER SER A . n 
A 1 741 GLN 741 741 741 GLN GLN A . n 
A 1 742 VAL 742 742 742 VAL VAL A . n 
A 1 743 ALA 743 743 743 ALA ALA A . n 
A 1 744 ILE 744 744 744 ILE ILE A . n 
A 1 745 PRO 745 745 745 PRO PRO A . n 
A 1 746 PHE 746 746 746 PHE PHE A . n 
A 1 747 ASP 747 747 747 ASP ASP A . n 
A 1 748 ASN 748 748 748 ASN ASN A . n 
A 1 749 VAL 749 749 749 VAL VAL A . n 
A 1 750 ASP 750 750 750 ASP ASP A . n 
A 1 751 ASP 751 751 751 ASP ASP A . n 
A 1 752 GLU 752 752 752 GLU GLU A . n 
A 1 753 GLN 753 753 753 GLN GLN A . n 
A 1 754 ILE 754 754 754 ILE ILE A . n 
A 1 755 GLN 755 755 755 GLN GLN A . n 
A 1 756 LYS 756 756 756 LYS LYS A . n 
A 1 757 PRO 757 757 757 PRO PRO A . n 
A 1 758 GLN 758 758 758 GLN GLN A . n 
A 1 759 ARG 759 759 759 ARG ARG A . n 
A 1 760 TRP 760 760 760 TRP TRP A . n 
A 1 761 ASN 761 761 761 ASN ASN A . n 
A 1 762 PRO 762 762 762 PRO PRO A . n 
A 1 763 ALA 763 763 763 ALA ALA A . n 
A 1 764 ASP 764 764 764 ASP ASP A . n 
A 1 765 LEU 765 765 765 LEU LEU A . n 
A 1 766 GLY 766 766 766 GLY GLY A . n 
A 1 767 ARG 767 767 767 ARG ARG A . n 
A 1 768 PHE 768 768 768 PHE PHE A . n 
A 1 769 MET 769 769 769 MET MET A . n 
A 1 770 ILE 770 770 770 ILE ILE A . n 
A 1 771 PHE 771 771 771 PHE PHE A . n 
A 1 772 PHE 772 772 772 PHE PHE A . n 
A 1 773 GLY 773 773 773 GLY GLY A . n 
A 1 774 PRO 774 774 774 PRO PRO A . n 
A 1 775 ILE 775 775 775 ILE ILE A . n 
A 1 776 SER 776 776 776 SER SER A . n 
A 1 777 SER 777 777 777 SER SER A . n 
A 1 778 ILE 778 778 778 ILE ILE A . n 
A 1 779 PHE 779 779 779 PHE PHE A . n 
A 1 780 ASP 780 780 780 ASP ASP A . n 
A 1 781 ILE 781 781 781 ILE ILE A . n 
A 1 782 LEU 782 782 782 LEU LEU A . n 
A 1 783 THR 783 783 783 THR THR A . n 
A 1 784 PHE 784 784 784 PHE PHE A . n 
A 1 785 CYS 785 785 785 CYS CYS A . n 
A 1 786 LEU 786 786 786 LEU LEU A . n 
A 1 787 MET 787 787 787 MET MET A . n 
A 1 788 TRP 788 788 788 TRP TRP A . n 
A 1 789 TRP 789 789 789 TRP TRP A . n 
A 1 790 VAL 790 790 790 VAL VAL A . n 
A 1 791 PHE 791 791 791 PHE PHE A . n 
A 1 792 HIS 792 792 792 HIS HIS A . n 
A 1 793 ALA 793 793 793 ALA ALA A . n 
A 1 794 ASN 794 794 794 ASN ASN A . n 
A 1 795 THR 795 795 795 THR THR A . n 
A 1 796 PRO 796 796 796 PRO PRO A . n 
A 1 797 GLU 797 797 797 GLU GLU A . n 
A 1 798 THR 798 798 798 THR THR A . n 
A 1 799 GLN 799 799 799 GLN GLN A . n 
A 1 800 THR 800 800 800 THR THR A . n 
A 1 801 LEU 801 801 801 LEU LEU A . n 
A 1 802 PHE 802 802 802 PHE PHE A . n 
A 1 803 GLN 803 803 803 GLN GLN A . n 
A 1 804 SER 804 804 804 SER SER A . n 
A 1 805 GLY 805 805 805 GLY GLY A . n 
A 1 806 TRP 806 806 806 TRP TRP A . n 
A 1 807 PHE 807 807 807 PHE PHE A . n 
A 1 808 VAL 808 808 808 VAL VAL A . n 
A 1 809 VAL 809 809 809 VAL VAL A . n 
A 1 810 GLY 810 810 810 GLY GLY A . n 
A 1 811 LEU 811 811 811 LEU LEU A . n 
A 1 812 LEU 812 812 812 LEU LEU A . n 
A 1 813 SER 813 813 813 SER SER A . n 
A 1 814 GLN 814 814 814 GLN GLN A . n 
A 1 815 THR 815 815 815 THR THR A . n 
A 1 816 LEU 816 816 816 LEU LEU A . n 
A 1 817 ILE 817 817 817 ILE ILE A . n 
A 1 818 VAL 818 818 818 VAL VAL A . n 
A 1 819 HIS 819 819 819 HIS HIS A . n 
A 1 820 MET 820 820 820 MET MET A . n 
A 1 821 ILE 821 821 821 ILE ILE A . n 
A 1 822 ARG 822 822 822 ARG ARG A . n 
A 1 823 THR 823 823 823 THR THR A . n 
A 1 824 ARG 824 824 824 ARG ARG A . n 
A 1 825 ARG 825 825 825 ARG ARG A . n 
A 1 826 VAL 826 826 826 VAL VAL A . n 
A 1 827 PRO 827 827 827 PRO PRO A . n 
A 1 828 PHE 828 828 828 PHE PHE A . n 
A 1 829 ILE 829 829 829 ILE ILE A . n 
A 1 830 GLN 830 830 830 GLN GLN A . n 
A 1 831 SER 831 831 831 SER SER A . n 
A 1 832 CYS 832 832 832 CYS CYS A . n 
A 1 833 ALA 833 833 833 ALA ALA A . n 
A 1 834 SER 834 834 834 SER SER A . n 
A 1 835 TRP 835 835 835 TRP TRP A . n 
A 1 836 PRO 836 836 836 PRO PRO A . n 
A 1 837 LEU 837 837 837 LEU LEU A . n 
A 1 838 MET 838 838 838 MET MET A . n 
A 1 839 ILE 839 839 839 ILE ILE A . n 
A 1 840 MET 840 840 840 MET MET A . n 
A 1 841 THR 841 841 841 THR THR A . n 
A 1 842 VAL 842 842 842 VAL VAL A . n 
A 1 843 ILE 843 843 843 ILE ILE A . n 
A 1 844 VAL 844 844 844 VAL VAL A . n 
A 1 845 MET 845 845 845 MET MET A . n 
A 1 846 ILE 846 846 846 ILE ILE A . n 
A 1 847 VAL 847 847 847 VAL VAL A . n 
A 1 848 GLY 848 848 848 GLY GLY A . n 
A 1 849 ILE 849 849 849 ILE ILE A . n 
A 1 850 ALA 850 850 850 ALA ALA A . n 
A 1 851 LEU 851 851 851 LEU LEU A . n 
A 1 852 PRO 852 852 852 PRO PRO A . n 
A 1 853 PHE 853 853 853 PHE PHE A . n 
A 1 854 SER 854 854 854 SER SER A . n 
A 1 855 PRO 855 855 855 PRO PRO A . n 
A 1 856 LEU 856 856 856 LEU LEU A . n 
A 1 857 ALA 857 857 857 ALA ALA A . n 
A 1 858 SER 858 858 858 SER SER A . n 
A 1 859 TYR 859 859 859 TYR TYR A . n 
A 1 860 LEU 860 860 860 LEU LEU A . n 
A 1 861 GLN 861 861 861 GLN GLN A . n 
A 1 862 LEU 862 862 862 LEU LEU A . n 
A 1 863 GLN 863 863 863 GLN GLN A . n 
A 1 864 ALA 864 864 864 ALA ALA A . n 
A 1 865 LEU 865 865 865 LEU LEU A . n 
A 1 866 PRO 866 866 866 PRO PRO A . n 
A 1 867 LEU 867 867 867 LEU LEU A . n 
A 1 868 SER 868 868 868 SER SER A . n 
A 1 869 TYR 869 869 869 TYR TYR A . n 
A 1 870 PHE 870 870 870 PHE PHE A . n 
A 1 871 PRO 871 871 871 PRO PRO A . n 
A 1 872 TRP 872 872 872 TRP TRP A . n 
A 1 873 LEU 873 873 873 LEU LEU A . n 
A 1 874 VAL 874 874 874 VAL VAL A . n 
A 1 875 ALA 875 875 875 ALA ALA A . n 
A 1 876 ILE 876 876 876 ILE ILE A . n 
A 1 877 LEU 877 877 877 LEU LEU A . n 
A 1 878 ALA 878 878 878 ALA ALA A . n 
A 1 879 GLY 879 879 879 GLY GLY A . n 
A 1 880 TYR 880 880 880 TYR TYR A . n 
A 1 881 MET 881 881 881 MET MET A . n 
A 1 882 THR 882 882 882 THR THR A . n 
A 1 883 LEU 883 883 883 LEU LEU A . n 
A 1 884 THR 884 884 884 THR THR A . n 
A 1 885 GLN 885 885 885 GLN GLN A . n 
A 1 886 LEU 886 886 886 LEU LEU A . n 
A 1 887 VAL 887 887 887 VAL VAL A . n 
A 1 888 LYS 888 888 888 LYS LYS A . n 
A 1 889 GLY 889 889 889 GLY GLY A . n 
A 1 890 PHE 890 890 890 PHE PHE A . n 
A 1 891 TYR 891 891 891 TYR TYR A . n 
A 1 892 SER 892 892 892 SER SER A . n 
A 1 893 ARG 893 893 ?   ?   ?   A . n 
A 1 894 ARG 894 894 ?   ?   ?   A . n 
A 1 895 TYR 895 895 ?   ?   ?   A . n 
A 1 896 GLY 896 896 ?   ?   ?   A . n 
A 1 897 TRP 897 897 ?   ?   ?   A . n 
A 1 898 GLN 898 898 ?   ?   ?   A . n 
A 1 899 HIS 899 899 ?   ?   ?   A . n 
A 1 900 HIS 900 900 ?   ?   ?   A . n 
A 1 901 HIS 901 901 ?   ?   ?   A . n 
A 1 902 HIS 902 902 ?   ?   ?   A . n 
A 1 903 HIS 903 903 ?   ?   ?   A . n 
A 1 904 HIS 904 904 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        MG 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   MG 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          MG 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     1001 
_pdbx_nonpoly_scheme.auth_seq_num    1001 
_pdbx_nonpoly_scheme.pdb_mon_id      MG 
_pdbx_nonpoly_scheme.auth_mon_id     MG 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A VAL 34  ? CG1 ? A VAL 34  CG1 
2   1 Y 1 A VAL 34  ? CG2 ? A VAL 34  CG2 
3   1 Y 1 A SER 37  ? OG  ? A SER 37  OG  
4   1 Y 1 A LEU 38  ? CG  ? A LEU 38  CG  
5   1 Y 1 A LEU 38  ? CD1 ? A LEU 38  CD1 
6   1 Y 1 A LEU 38  ? CD2 ? A LEU 38  CD2 
7   1 Y 1 A SER 39  ? OG  ? A SER 39  OG  
8   1 Y 1 A HIS 41  ? CG  ? A HIS 41  CG  
9   1 Y 1 A HIS 41  ? ND1 ? A HIS 41  ND1 
10  1 Y 1 A HIS 41  ? CD2 ? A HIS 41  CD2 
11  1 Y 1 A HIS 41  ? CE1 ? A HIS 41  CE1 
12  1 Y 1 A HIS 41  ? NE2 ? A HIS 41  NE2 
13  1 Y 1 A CYS 42  ? SG  ? A CYS 42  SG  
14  1 Y 1 A LEU 43  ? CG  ? A LEU 43  CG  
15  1 Y 1 A LEU 43  ? CD1 ? A LEU 43  CD1 
16  1 Y 1 A LEU 43  ? CD2 ? A LEU 43  CD2 
17  1 Y 1 A LYS 44  ? CG  ? A LYS 44  CG  
18  1 Y 1 A LYS 44  ? CD  ? A LYS 44  CD  
19  1 Y 1 A LYS 44  ? CE  ? A LYS 44  CE  
20  1 Y 1 A LYS 44  ? NZ  ? A LYS 44  NZ  
21  1 Y 1 A MET 45  ? CG  ? A MET 45  CG  
22  1 Y 1 A MET 45  ? SD  ? A MET 45  SD  
23  1 Y 1 A MET 45  ? CE  ? A MET 45  CE  
24  1 Y 1 A VAL 47  ? CG1 ? A VAL 47  CG1 
25  1 Y 1 A VAL 47  ? CG2 ? A VAL 47  CG2 
26  1 Y 1 A MET 48  ? CG  ? A MET 48  CG  
27  1 Y 1 A MET 48  ? SD  ? A MET 48  SD  
28  1 Y 1 A MET 48  ? CE  ? A MET 48  CE  
29  1 Y 1 A GLU 50  ? CG  ? A GLU 50  CG  
30  1 Y 1 A GLU 50  ? CD  ? A GLU 50  CD  
31  1 Y 1 A GLU 50  ? OE1 ? A GLU 50  OE1 
32  1 Y 1 A GLU 50  ? OE2 ? A GLU 50  OE2 
33  1 Y 1 A GLU 51  ? CG  ? A GLU 51  CG  
34  1 Y 1 A GLU 51  ? CD  ? A GLU 51  CD  
35  1 Y 1 A GLU 51  ? OE1 ? A GLU 51  OE1 
36  1 Y 1 A GLU 51  ? OE2 ? A GLU 51  OE2 
37  1 Y 1 A GLU 52  ? CG  ? A GLU 52  CG  
38  1 Y 1 A GLU 52  ? CD  ? A GLU 52  CD  
39  1 Y 1 A GLU 52  ? OE1 ? A GLU 52  OE1 
40  1 Y 1 A GLU 52  ? OE2 ? A GLU 52  OE2 
41  1 Y 1 A LEU 53  ? CG  ? A LEU 53  CG  
42  1 Y 1 A LEU 53  ? CD1 ? A LEU 53  CD1 
43  1 Y 1 A LEU 53  ? CD2 ? A LEU 53  CD2 
44  1 Y 1 A TRP 54  ? CG  ? A TRP 54  CG  
45  1 Y 1 A TRP 54  ? CD1 ? A TRP 54  CD1 
46  1 Y 1 A TRP 54  ? CD2 ? A TRP 54  CD2 
47  1 Y 1 A TRP 54  ? NE1 ? A TRP 54  NE1 
48  1 Y 1 A TRP 54  ? CE2 ? A TRP 54  CE2 
49  1 Y 1 A TRP 54  ? CE3 ? A TRP 54  CE3 
50  1 Y 1 A TRP 54  ? CZ2 ? A TRP 54  CZ2 
51  1 Y 1 A TRP 54  ? CZ3 ? A TRP 54  CZ3 
52  1 Y 1 A TRP 54  ? CH2 ? A TRP 54  CH2 
53  1 Y 1 A LYS 55  ? CG  ? A LYS 55  CG  
54  1 Y 1 A LYS 55  ? CD  ? A LYS 55  CD  
55  1 Y 1 A LYS 55  ? CE  ? A LYS 55  CE  
56  1 Y 1 A LYS 55  ? NZ  ? A LYS 55  NZ  
57  1 Y 1 A THR 56  ? OG1 ? A THR 56  OG1 
58  1 Y 1 A THR 56  ? CG2 ? A THR 56  CG2 
59  1 Y 1 A PHE 57  ? CG  ? A PHE 57  CG  
60  1 Y 1 A PHE 57  ? CD1 ? A PHE 57  CD1 
61  1 Y 1 A PHE 57  ? CD2 ? A PHE 57  CD2 
62  1 Y 1 A PHE 57  ? CE1 ? A PHE 57  CE1 
63  1 Y 1 A PHE 57  ? CE2 ? A PHE 57  CE2 
64  1 Y 1 A PHE 57  ? CZ  ? A PHE 57  CZ  
65  1 Y 1 A THR 59  ? OG1 ? A THR 59  OG1 
66  1 Y 1 A THR 59  ? CG2 ? A THR 59  CG2 
67  1 Y 1 A HIS 60  ? CG  ? A HIS 60  CG  
68  1 Y 1 A HIS 60  ? ND1 ? A HIS 60  ND1 
69  1 Y 1 A HIS 60  ? CD2 ? A HIS 60  CD2 
70  1 Y 1 A HIS 60  ? CE1 ? A HIS 60  CE1 
71  1 Y 1 A HIS 60  ? NE2 ? A HIS 60  NE2 
72  1 Y 1 A GLU 62  ? CG  ? A GLU 62  CG  
73  1 Y 1 A GLU 62  ? CD  ? A GLU 62  CD  
74  1 Y 1 A GLU 62  ? OE1 ? A GLU 62  OE1 
75  1 Y 1 A GLU 62  ? OE2 ? A GLU 62  OE2 
76  1 Y 1 A LEU 64  ? CG  ? A LEU 64  CG  
77  1 Y 1 A LEU 64  ? CD1 ? A LEU 64  CD1 
78  1 Y 1 A LEU 64  ? CD2 ? A LEU 64  CD2 
79  1 Y 1 A ASN 65  ? CG  ? A ASN 65  CG  
80  1 Y 1 A ASN 65  ? OD1 ? A ASN 65  OD1 
81  1 Y 1 A ASN 65  ? ND2 ? A ASN 65  ND2 
82  1 Y 1 A GLN 66  ? CG  ? A GLN 66  CG  
83  1 Y 1 A GLN 66  ? CD  ? A GLN 66  CD  
84  1 Y 1 A GLN 66  ? OE1 ? A GLN 66  OE1 
85  1 Y 1 A GLN 66  ? NE2 ? A GLN 66  NE2 
86  1 Y 1 A GLU 68  ? CG  ? A GLU 68  CG  
87  1 Y 1 A GLU 68  ? CD  ? A GLU 68  CD  
88  1 Y 1 A GLU 68  ? OE1 ? A GLU 68  OE1 
89  1 Y 1 A GLU 68  ? OE2 ? A GLU 68  OE2 
90  1 Y 1 A VAL 69  ? CG1 ? A VAL 69  CG1 
91  1 Y 1 A VAL 69  ? CG2 ? A VAL 69  CG2 
92  1 Y 1 A GLU 70  ? CG  ? A GLU 70  CG  
93  1 Y 1 A GLU 70  ? CD  ? A GLU 70  CD  
94  1 Y 1 A GLU 70  ? OE1 ? A GLU 70  OE1 
95  1 Y 1 A GLU 70  ? OE2 ? A GLU 70  OE2 
96  1 Y 1 A SER 71  ? OG  ? A SER 71  OG  
97  1 Y 1 A ARG 73  ? CG  ? A ARG 73  CG  
98  1 Y 1 A ARG 73  ? CD  ? A ARG 73  CD  
99  1 Y 1 A ARG 73  ? NE  ? A ARG 73  NE  
100 1 Y 1 A ARG 73  ? CZ  ? A ARG 73  CZ  
101 1 Y 1 A ARG 73  ? NH1 ? A ARG 73  NH1 
102 1 Y 1 A ARG 73  ? NH2 ? A ARG 73  NH2 
103 1 Y 1 A GLU 74  ? CG  ? A GLU 74  CG  
104 1 Y 1 A GLU 74  ? CD  ? A GLU 74  CD  
105 1 Y 1 A GLU 74  ? OE1 ? A GLU 74  OE1 
106 1 Y 1 A GLU 74  ? OE2 ? A GLU 74  OE2 
107 1 Y 1 A GLN 75  ? CG  ? A GLN 75  CG  
108 1 Y 1 A GLN 75  ? CD  ? A GLN 75  CD  
109 1 Y 1 A GLN 75  ? OE1 ? A GLN 75  OE1 
110 1 Y 1 A GLN 75  ? NE2 ? A GLN 75  NE2 
111 1 Y 1 A HIS 76  ? CG  ? A HIS 76  CG  
112 1 Y 1 A HIS 76  ? ND1 ? A HIS 76  ND1 
113 1 Y 1 A HIS 76  ? CD2 ? A HIS 76  CD2 
114 1 Y 1 A HIS 76  ? CE1 ? A HIS 76  CE1 
115 1 Y 1 A HIS 76  ? NE2 ? A HIS 76  NE2 
116 1 Y 1 A GLU 78  ? CG  ? A GLU 78  CG  
117 1 Y 1 A GLU 78  ? CD  ? A GLU 78  CD  
118 1 Y 1 A GLU 78  ? OE1 ? A GLU 78  OE1 
119 1 Y 1 A GLU 78  ? OE2 ? A GLU 78  OE2 
120 1 Y 1 A ASN 79  ? CG  ? A ASN 79  CG  
121 1 Y 1 A ASN 79  ? OD1 ? A ASN 79  OD1 
122 1 Y 1 A ASN 79  ? ND2 ? A ASN 79  ND2 
123 1 Y 1 A LYS 80  ? CG  ? A LYS 80  CG  
124 1 Y 1 A LYS 80  ? CD  ? A LYS 80  CD  
125 1 Y 1 A LYS 80  ? CE  ? A LYS 80  CE  
126 1 Y 1 A LYS 80  ? NZ  ? A LYS 80  NZ  
127 1 Y 1 A LEU 81  ? CG  ? A LEU 81  CG  
128 1 Y 1 A LEU 81  ? CD1 ? A LEU 81  CD1 
129 1 Y 1 A LEU 81  ? CD2 ? A LEU 81  CD2 
130 1 Y 1 A GLN 84  ? CG  ? A GLN 84  CG  
131 1 Y 1 A GLN 84  ? CD  ? A GLN 84  CD  
132 1 Y 1 A GLN 84  ? OE1 ? A GLN 84  OE1 
133 1 Y 1 A GLN 84  ? NE2 ? A GLN 84  NE2 
134 1 Y 1 A GLN 85  ? CG  ? A GLN 85  CG  
135 1 Y 1 A GLN 85  ? CD  ? A GLN 85  CD  
136 1 Y 1 A GLN 85  ? OE1 ? A GLN 85  OE1 
137 1 Y 1 A GLN 85  ? NE2 ? A GLN 85  NE2 
138 1 Y 1 A SER 87  ? OG  ? A SER 87  OG  
139 1 Y 1 A TRP 89  ? CG  ? A TRP 89  CG  
140 1 Y 1 A TRP 89  ? CD1 ? A TRP 89  CD1 
141 1 Y 1 A TRP 89  ? CD2 ? A TRP 89  CD2 
142 1 Y 1 A TRP 89  ? NE1 ? A TRP 89  NE1 
143 1 Y 1 A TRP 89  ? CE2 ? A TRP 89  CE2 
144 1 Y 1 A TRP 89  ? CE3 ? A TRP 89  CE3 
145 1 Y 1 A TRP 89  ? CZ2 ? A TRP 89  CZ2 
146 1 Y 1 A TRP 89  ? CZ3 ? A TRP 89  CZ3 
147 1 Y 1 A TRP 89  ? CH2 ? A TRP 89  CH2 
148 1 Y 1 A TRP 90  ? CG  ? A TRP 90  CG  
149 1 Y 1 A TRP 90  ? CD1 ? A TRP 90  CD1 
150 1 Y 1 A TRP 90  ? CD2 ? A TRP 90  CD2 
151 1 Y 1 A TRP 90  ? NE1 ? A TRP 90  NE1 
152 1 Y 1 A TRP 90  ? CE2 ? A TRP 90  CE2 
153 1 Y 1 A TRP 90  ? CE3 ? A TRP 90  CE3 
154 1 Y 1 A TRP 90  ? CZ2 ? A TRP 90  CZ2 
155 1 Y 1 A TRP 90  ? CZ3 ? A TRP 90  CZ3 
156 1 Y 1 A TRP 90  ? CH2 ? A TRP 90  CH2 
157 1 Y 1 A VAL 91  ? CG1 ? A VAL 91  CG1 
158 1 Y 1 A VAL 91  ? CG2 ? A VAL 91  CG2 
159 1 Y 1 A GLU 139 ? CG  ? A GLU 139 CG  
160 1 Y 1 A GLU 139 ? CD  ? A GLU 139 CD  
161 1 Y 1 A GLU 139 ? OE1 ? A GLU 139 OE1 
162 1 Y 1 A GLU 139 ? OE2 ? A GLU 139 OE2 
163 1 Y 1 A ARG 141 ? CG  ? A ARG 141 CG  
164 1 Y 1 A ARG 141 ? CD  ? A ARG 141 CD  
165 1 Y 1 A ARG 141 ? NE  ? A ARG 141 NE  
166 1 Y 1 A ARG 141 ? CZ  ? A ARG 141 CZ  
167 1 Y 1 A ARG 141 ? NH1 ? A ARG 141 NH1 
168 1 Y 1 A ARG 141 ? NH2 ? A ARG 141 NH2 
169 1 Y 1 A THR 143 ? OG1 ? A THR 143 OG1 
170 1 Y 1 A THR 143 ? CG2 ? A THR 143 CG2 
171 1 Y 1 A LYS 144 ? CG  ? A LYS 144 CG  
172 1 Y 1 A LYS 144 ? CD  ? A LYS 144 CD  
173 1 Y 1 A LYS 144 ? CE  ? A LYS 144 CE  
174 1 Y 1 A LYS 144 ? NZ  ? A LYS 144 NZ  
175 1 Y 1 A ASP 147 ? CG  ? A ASP 147 CG  
176 1 Y 1 A ASP 147 ? OD1 ? A ASP 147 OD1 
177 1 Y 1 A ASP 147 ? OD2 ? A ASP 147 OD2 
178 1 Y 1 A LEU 149 ? CG  ? A LEU 149 CG  
179 1 Y 1 A LEU 149 ? CD1 ? A LEU 149 CD1 
180 1 Y 1 A LEU 149 ? CD2 ? A LEU 149 CD2 
181 1 Y 1 A LYS 150 ? CG  ? A LYS 150 CG  
182 1 Y 1 A LYS 150 ? CD  ? A LYS 150 CD  
183 1 Y 1 A LYS 150 ? CE  ? A LYS 150 CE  
184 1 Y 1 A LYS 150 ? NZ  ? A LYS 150 NZ  
185 1 Y 1 A MET 152 ? CG  ? A MET 152 CG  
186 1 Y 1 A MET 152 ? SD  ? A MET 152 SD  
187 1 Y 1 A MET 152 ? CE  ? A MET 152 CE  
188 1 Y 1 A VAL 153 ? CG1 ? A VAL 153 CG1 
189 1 Y 1 A VAL 153 ? CG2 ? A VAL 153 CG2 
190 1 Y 1 A SER 154 ? OG  ? A SER 154 OG  
191 1 Y 1 A ASN 155 ? CG  ? A ASN 155 CG  
192 1 Y 1 A ASN 155 ? OD1 ? A ASN 155 OD1 
193 1 Y 1 A ASN 155 ? ND2 ? A ASN 155 ND2 
194 1 Y 1 A THR 156 ? OG1 ? A THR 156 OG1 
195 1 Y 1 A THR 156 ? CG2 ? A THR 156 CG2 
196 1 Y 1 A THR 158 ? OG1 ? A THR 158 OG1 
197 1 Y 1 A THR 158 ? CG2 ? A THR 158 CG2 
198 1 Y 1 A VAL 159 ? CG1 ? A VAL 159 CG1 
199 1 Y 1 A VAL 159 ? CG2 ? A VAL 159 CG2 
200 1 Y 1 A LEU 160 ? CG  ? A LEU 160 CG  
201 1 Y 1 A LEU 160 ? CD1 ? A LEU 160 CD1 
202 1 Y 1 A LEU 160 ? CD2 ? A LEU 160 CD2 
203 1 Y 1 A ARG 161 ? CG  ? A ARG 161 CG  
204 1 Y 1 A ARG 161 ? CD  ? A ARG 161 CD  
205 1 Y 1 A ARG 161 ? NE  ? A ARG 161 NE  
206 1 Y 1 A ARG 161 ? CZ  ? A ARG 161 CZ  
207 1 Y 1 A ARG 161 ? NH1 ? A ARG 161 NH1 
208 1 Y 1 A ARG 161 ? NH2 ? A ARG 161 NH2 
209 1 Y 1 A VAL 162 ? CG1 ? A VAL 162 CG1 
210 1 Y 1 A VAL 162 ? CG2 ? A VAL 162 CG2 
211 1 Y 1 A ILE 163 ? CG1 ? A ILE 163 CG1 
212 1 Y 1 A ILE 163 ? CG2 ? A ILE 163 CG2 
213 1 Y 1 A ILE 163 ? CD1 ? A ILE 163 CD1 
214 1 Y 1 A ASN 164 ? CG  ? A ASN 164 CG  
215 1 Y 1 A ASN 164 ? OD1 ? A ASN 164 OD1 
216 1 Y 1 A ASN 164 ? ND2 ? A ASN 164 ND2 
217 1 Y 1 A ASP 165 ? CG  ? A ASP 165 CG  
218 1 Y 1 A ASP 165 ? OD1 ? A ASP 165 OD1 
219 1 Y 1 A ASP 165 ? OD2 ? A ASP 165 OD2 
220 1 Y 1 A LYS 166 ? CG  ? A LYS 166 CG  
221 1 Y 1 A LYS 166 ? CD  ? A LYS 166 CD  
222 1 Y 1 A LYS 166 ? CE  ? A LYS 166 CE  
223 1 Y 1 A LYS 166 ? NZ  ? A LYS 166 NZ  
224 1 Y 1 A GLU 168 ? CG  ? A GLU 168 CG  
225 1 Y 1 A GLU 168 ? CD  ? A GLU 168 CD  
226 1 Y 1 A GLU 168 ? OE1 ? A GLU 168 OE1 
227 1 Y 1 A GLU 168 ? OE2 ? A GLU 168 OE2 
228 1 Y 1 A ASN 169 ? CG  ? A ASN 169 CG  
229 1 Y 1 A ASN 169 ? OD1 ? A ASN 169 OD1 
230 1 Y 1 A ASN 169 ? ND2 ? A ASN 169 ND2 
231 1 Y 1 A TRP 171 ? CG  ? A TRP 171 CG  
232 1 Y 1 A TRP 171 ? CD1 ? A TRP 171 CD1 
233 1 Y 1 A TRP 171 ? CD2 ? A TRP 171 CD2 
234 1 Y 1 A TRP 171 ? NE1 ? A TRP 171 NE1 
235 1 Y 1 A TRP 171 ? CE2 ? A TRP 171 CE2 
236 1 Y 1 A TRP 171 ? CE3 ? A TRP 171 CE3 
237 1 Y 1 A TRP 171 ? CZ2 ? A TRP 171 CZ2 
238 1 Y 1 A TRP 171 ? CZ3 ? A TRP 171 CZ3 
239 1 Y 1 A TRP 171 ? CH2 ? A TRP 171 CH2 
240 1 Y 1 A LEU 172 ? CG  ? A LEU 172 CG  
241 1 Y 1 A LEU 172 ? CD1 ? A LEU 172 CD1 
242 1 Y 1 A LEU 172 ? CD2 ? A LEU 172 CD2 
243 1 Y 1 A GLU 173 ? CG  ? A GLU 173 CG  
244 1 Y 1 A GLU 173 ? CD  ? A GLU 173 CD  
245 1 Y 1 A GLU 173 ? OE1 ? A GLU 173 OE1 
246 1 Y 1 A GLU 173 ? OE2 ? A GLU 173 OE2 
247 1 Y 1 A ILE 174 ? CG1 ? A ILE 174 CG1 
248 1 Y 1 A ILE 174 ? CG2 ? A ILE 174 CG2 
249 1 Y 1 A ILE 174 ? CD1 ? A ILE 174 CD1 
250 1 Y 1 A ILE 176 ? CG1 ? A ILE 176 CG1 
251 1 Y 1 A ILE 176 ? CG2 ? A ILE 176 CG2 
252 1 Y 1 A ILE 176 ? CD1 ? A ILE 176 CD1 
253 1 Y 1 A ASP 177 ? CG  ? A ASP 177 CG  
254 1 Y 1 A ASP 177 ? OD1 ? A ASP 177 OD1 
255 1 Y 1 A ASP 177 ? OD2 ? A ASP 177 OD2 
256 1 Y 1 A GLN 178 ? CG  ? A GLN 178 CG  
257 1 Y 1 A GLN 178 ? CD  ? A GLN 178 CD  
258 1 Y 1 A GLN 178 ? OE1 ? A GLN 178 OE1 
259 1 Y 1 A GLN 178 ? NE2 ? A GLN 178 NE2 
260 1 Y 1 A LEU 179 ? CG  ? A LEU 179 CG  
261 1 Y 1 A LEU 179 ? CD1 ? A LEU 179 CD1 
262 1 Y 1 A LEU 179 ? CD2 ? A LEU 179 CD2 
263 1 Y 1 A VAL 180 ? CG1 ? A VAL 180 CG1 
264 1 Y 1 A VAL 180 ? CG2 ? A VAL 180 CG2 
265 1 Y 1 A ASP 183 ? CG  ? A ASP 183 CG  
266 1 Y 1 A ASP 183 ? OD1 ? A ASP 183 OD1 
267 1 Y 1 A ASP 183 ? OD2 ? A ASP 183 OD2 
268 1 Y 1 A ILE 184 ? CG1 ? A ILE 184 CG1 
269 1 Y 1 A ILE 184 ? CG2 ? A ILE 184 CG2 
270 1 Y 1 A ILE 184 ? CD1 ? A ILE 184 CD1 
271 1 Y 1 A ILE 185 ? CG1 ? A ILE 185 CG1 
272 1 Y 1 A ILE 185 ? CG2 ? A ILE 185 CG2 
273 1 Y 1 A ILE 185 ? CD1 ? A ILE 185 CD1 
274 1 Y 1 A LYS 186 ? CG  ? A LYS 186 CG  
275 1 Y 1 A LYS 186 ? CD  ? A LYS 186 CD  
276 1 Y 1 A LYS 186 ? CE  ? A LYS 186 CE  
277 1 Y 1 A LYS 186 ? NZ  ? A LYS 186 NZ  
278 1 Y 1 A LEU 187 ? CG  ? A LEU 187 CG  
279 1 Y 1 A LEU 187 ? CD1 ? A LEU 187 CD1 
280 1 Y 1 A LEU 187 ? CD2 ? A LEU 187 CD2 
281 1 Y 1 A ASP 191 ? CG  ? A ASP 191 CG  
282 1 Y 1 A ASP 191 ? OD1 ? A ASP 191 OD1 
283 1 Y 1 A ASP 191 ? OD2 ? A ASP 191 OD2 
284 1 Y 1 A MET 192 ? CG  ? A MET 192 CG  
285 1 Y 1 A MET 192 ? SD  ? A MET 192 SD  
286 1 Y 1 A MET 192 ? CE  ? A MET 192 CE  
287 1 Y 1 A ILE 193 ? CG1 ? A ILE 193 CG1 
288 1 Y 1 A ILE 193 ? CG2 ? A ILE 193 CG2 
289 1 Y 1 A ILE 193 ? CD1 ? A ILE 193 CD1 
290 1 Y 1 A ASP 196 ? CG  ? A ASP 196 CG  
291 1 Y 1 A ASP 196 ? OD1 ? A ASP 196 OD1 
292 1 Y 1 A ASP 196 ? OD2 ? A ASP 196 OD2 
293 1 Y 1 A LEU 197 ? CG  ? A LEU 197 CG  
294 1 Y 1 A LEU 197 ? CD1 ? A LEU 197 CD1 
295 1 Y 1 A LEU 197 ? CD2 ? A LEU 197 CD2 
296 1 Y 1 A ARG 198 ? CG  ? A ARG 198 CG  
297 1 Y 1 A ARG 198 ? CD  ? A ARG 198 CD  
298 1 Y 1 A ARG 198 ? NE  ? A ARG 198 NE  
299 1 Y 1 A ARG 198 ? CZ  ? A ARG 198 CZ  
300 1 Y 1 A ARG 198 ? NH1 ? A ARG 198 NH1 
301 1 Y 1 A ARG 198 ? NH2 ? A ARG 198 NH2 
302 1 Y 1 A ILE 199 ? CG1 ? A ILE 199 CG1 
303 1 Y 1 A ILE 199 ? CG2 ? A ILE 199 CG2 
304 1 Y 1 A ILE 199 ? CD1 ? A ILE 199 CD1 
305 1 Y 1 A LEU 200 ? CG  ? A LEU 200 CG  
306 1 Y 1 A LEU 200 ? CD1 ? A LEU 200 CD1 
307 1 Y 1 A LEU 200 ? CD2 ? A LEU 200 CD2 
308 1 Y 1 A GLN 201 ? CG  ? A GLN 201 CG  
309 1 Y 1 A GLN 201 ? CD  ? A GLN 201 CD  
310 1 Y 1 A GLN 201 ? OE1 ? A GLN 201 OE1 
311 1 Y 1 A GLN 201 ? NE2 ? A GLN 201 NE2 
312 1 Y 1 A ARG 203 ? CG  ? A ARG 203 CG  
313 1 Y 1 A ARG 203 ? CD  ? A ARG 203 CD  
314 1 Y 1 A ARG 203 ? NE  ? A ARG 203 NE  
315 1 Y 1 A ARG 203 ? CZ  ? A ARG 203 CZ  
316 1 Y 1 A ARG 203 ? NH1 ? A ARG 203 NH1 
317 1 Y 1 A ARG 203 ? NH2 ? A ARG 203 NH2 
318 1 Y 1 A ASP 204 ? CG  ? A ASP 204 CG  
319 1 Y 1 A ASP 204 ? OD1 ? A ASP 204 OD1 
320 1 Y 1 A ASP 204 ? OD2 ? A ASP 204 OD2 
321 1 Y 1 A LEU 205 ? CG  ? A LEU 205 CG  
322 1 Y 1 A LEU 205 ? CD1 ? A LEU 205 CD1 
323 1 Y 1 A LEU 205 ? CD2 ? A LEU 205 CD2 
324 1 Y 1 A PHE 206 ? CG  ? A PHE 206 CG  
325 1 Y 1 A PHE 206 ? CD1 ? A PHE 206 CD1 
326 1 Y 1 A PHE 206 ? CD2 ? A PHE 206 CD2 
327 1 Y 1 A PHE 206 ? CE1 ? A PHE 206 CE1 
328 1 Y 1 A PHE 206 ? CE2 ? A PHE 206 CE2 
329 1 Y 1 A PHE 206 ? CZ  ? A PHE 206 CZ  
330 1 Y 1 A VAL 207 ? CG1 ? A VAL 207 CG1 
331 1 Y 1 A VAL 207 ? CG2 ? A VAL 207 CG2 
332 1 Y 1 A GLN 209 ? CG  ? A GLN 209 CG  
333 1 Y 1 A GLN 209 ? CD  ? A GLN 209 CD  
334 1 Y 1 A GLN 209 ? OE1 ? A GLN 209 OE1 
335 1 Y 1 A GLN 209 ? NE2 ? A GLN 209 NE2 
336 1 Y 1 A SER 211 ? OG  ? A SER 211 OG  
337 1 Y 1 A LEU 212 ? CG  ? A LEU 212 CG  
338 1 Y 1 A LEU 212 ? CD1 ? A LEU 212 CD1 
339 1 Y 1 A LEU 212 ? CD2 ? A LEU 212 CD2 
340 1 Y 1 A THR 213 ? OG1 ? A THR 213 OG1 
341 1 Y 1 A THR 213 ? CG2 ? A THR 213 CG2 
342 1 Y 1 A GLU 215 ? CG  ? A GLU 215 CG  
343 1 Y 1 A GLU 215 ? CD  ? A GLU 215 CD  
344 1 Y 1 A GLU 215 ? OE1 ? A GLU 215 OE1 
345 1 Y 1 A GLU 215 ? OE2 ? A GLU 215 OE2 
346 1 Y 1 A SER 216 ? OG  ? A SER 216 OG  
347 1 Y 1 A LEU 217 ? CG  ? A LEU 217 CG  
348 1 Y 1 A LEU 217 ? CD1 ? A LEU 217 CD1 
349 1 Y 1 A LEU 217 ? CD2 ? A LEU 217 CD2 
350 1 Y 1 A VAL 219 ? CG1 ? A VAL 219 CG1 
351 1 Y 1 A VAL 219 ? CG2 ? A VAL 219 CG2 
352 1 Y 1 A GLU 220 ? CG  ? A GLU 220 CG  
353 1 Y 1 A GLU 220 ? CD  ? A GLU 220 CD  
354 1 Y 1 A GLU 220 ? OE1 ? A GLU 220 OE1 
355 1 Y 1 A GLU 220 ? OE2 ? A GLU 220 OE2 
356 1 Y 1 A LYS 221 ? CG  ? A LYS 221 CG  
357 1 Y 1 A LYS 221 ? CD  ? A LYS 221 CD  
358 1 Y 1 A LYS 221 ? CE  ? A LYS 221 CE  
359 1 Y 1 A LYS 221 ? NZ  ? A LYS 221 NZ  
360 1 Y 1 A THR 224 ? OG1 ? A THR 224 OG1 
361 1 Y 1 A THR 224 ? CG2 ? A THR 224 CG2 
362 1 Y 1 A THR 225 ? OG1 ? A THR 225 OG1 
363 1 Y 1 A THR 225 ? CG2 ? A THR 225 CG2 
364 1 Y 1 A ARG 226 ? CG  ? A ARG 226 CG  
365 1 Y 1 A ARG 226 ? CD  ? A ARG 226 CD  
366 1 Y 1 A ARG 226 ? NE  ? A ARG 226 NE  
367 1 Y 1 A ARG 226 ? CZ  ? A ARG 226 CZ  
368 1 Y 1 A ARG 226 ? NH1 ? A ARG 226 NH1 
369 1 Y 1 A ARG 226 ? NH2 ? A ARG 226 NH2 
370 1 Y 1 A GLN 227 ? CG  ? A GLN 227 CG  
371 1 Y 1 A GLN 227 ? CD  ? A GLN 227 CD  
372 1 Y 1 A GLN 227 ? OE1 ? A GLN 227 OE1 
373 1 Y 1 A GLN 227 ? NE2 ? A GLN 227 NE2 
374 1 Y 1 A GLU 229 ? CG  ? A GLU 229 CG  
375 1 Y 1 A GLU 229 ? CD  ? A GLU 229 CD  
376 1 Y 1 A GLU 229 ? OE1 ? A GLU 229 OE1 
377 1 Y 1 A GLU 229 ? OE2 ? A GLU 229 OE2 
378 1 Y 1 A HIS 230 ? CG  ? A HIS 230 CG  
379 1 Y 1 A HIS 230 ? ND1 ? A HIS 230 ND1 
380 1 Y 1 A HIS 230 ? CD2 ? A HIS 230 CD2 
381 1 Y 1 A HIS 230 ? CE1 ? A HIS 230 CE1 
382 1 Y 1 A HIS 230 ? NE2 ? A HIS 230 NE2 
383 1 Y 1 A SER 231 ? OG  ? A SER 231 OG  
384 1 Y 1 A ASN 232 ? CG  ? A ASN 232 CG  
385 1 Y 1 A ASN 232 ? OD1 ? A ASN 232 OD1 
386 1 Y 1 A ASN 232 ? ND2 ? A ASN 232 ND2 
387 1 Y 1 A LEU 234 ? CG  ? A LEU 234 CG  
388 1 Y 1 A LEU 234 ? CD1 ? A LEU 234 CD1 
389 1 Y 1 A LEU 234 ? CD2 ? A LEU 234 CD2 
390 1 Y 1 A GLU 235 ? CG  ? A GLU 235 CG  
391 1 Y 1 A GLU 235 ? CD  ? A GLU 235 CD  
392 1 Y 1 A GLU 235 ? OE1 ? A GLU 235 OE1 
393 1 Y 1 A GLU 235 ? OE2 ? A GLU 235 OE2 
394 1 Y 1 A CYS 236 ? SG  ? A CYS 236 SG  
395 1 Y 1 A ASP 237 ? CG  ? A ASP 237 CG  
396 1 Y 1 A ASP 237 ? OD1 ? A ASP 237 OD1 
397 1 Y 1 A ASP 237 ? OD2 ? A ASP 237 OD2 
398 1 Y 1 A THR 238 ? OG1 ? A THR 238 OG1 
399 1 Y 1 A THR 238 ? CG2 ? A THR 238 CG2 
400 1 Y 1 A LEU 239 ? CG  ? A LEU 239 CG  
401 1 Y 1 A LEU 239 ? CD1 ? A LEU 239 CD1 
402 1 Y 1 A LEU 239 ? CD2 ? A LEU 239 CD2 
403 1 Y 1 A CYS 240 ? SG  ? A CYS 240 SG  
404 1 Y 1 A MET 242 ? CG  ? A MET 242 CG  
405 1 Y 1 A MET 242 ? SD  ? A MET 242 SD  
406 1 Y 1 A MET 242 ? CE  ? A MET 242 CE  
407 1 Y 1 A THR 244 ? OG1 ? A THR 244 OG1 
408 1 Y 1 A THR 244 ? CG2 ? A THR 244 CG2 
409 1 Y 1 A THR 245 ? OG1 ? A THR 245 OG1 
410 1 Y 1 A THR 245 ? CG2 ? A THR 245 CG2 
411 1 Y 1 A VAL 246 ? CG1 ? A VAL 246 CG1 
412 1 Y 1 A VAL 246 ? CG2 ? A VAL 246 CG2 
413 1 Y 1 A VAL 247 ? CG1 ? A VAL 247 CG1 
414 1 Y 1 A VAL 247 ? CG2 ? A VAL 247 CG2 
415 1 Y 1 A SER 248 ? OG  ? A SER 248 OG  
416 1 Y 1 A THR 250 ? OG1 ? A THR 250 OG1 
417 1 Y 1 A THR 250 ? CG2 ? A THR 250 CG2 
418 1 Y 1 A GLN 252 ? CG  ? A GLN 252 CG  
419 1 Y 1 A GLN 252 ? CD  ? A GLN 252 CD  
420 1 Y 1 A GLN 252 ? OE1 ? A GLN 252 OE1 
421 1 Y 1 A GLN 252 ? NE2 ? A GLN 252 NE2 
422 1 Y 1 A MET 254 ? CG  ? A MET 254 CG  
423 1 Y 1 A MET 254 ? SD  ? A MET 254 SD  
424 1 Y 1 A MET 254 ? CE  ? A MET 254 CE  
425 1 Y 1 A VAL 255 ? CG1 ? A VAL 255 CG1 
426 1 Y 1 A VAL 255 ? CG2 ? A VAL 255 CG2 
427 1 Y 1 A ILE 256 ? CG1 ? A ILE 256 CG1 
428 1 Y 1 A ILE 256 ? CG2 ? A ILE 256 CG2 
429 1 Y 1 A ILE 256 ? CD1 ? A ILE 256 CD1 
430 1 Y 1 A THR 258 ? OG1 ? A THR 258 OG1 
431 1 Y 1 A THR 258 ? CG2 ? A THR 258 CG2 
432 1 Y 1 A ASN 261 ? CG  ? A ASN 261 CG  
433 1 Y 1 A ASN 261 ? OD1 ? A ASN 261 OD1 
434 1 Y 1 A ASN 261 ? ND2 ? A ASN 261 ND2 
435 1 Y 1 A THR 262 ? OG1 ? A THR 262 OG1 
436 1 Y 1 A THR 262 ? CG2 ? A THR 262 CG2 
437 1 Y 1 A TRP 263 ? CG  ? A TRP 263 CG  
438 1 Y 1 A TRP 263 ? CD1 ? A TRP 263 CD1 
439 1 Y 1 A TRP 263 ? CD2 ? A TRP 263 CD2 
440 1 Y 1 A TRP 263 ? NE1 ? A TRP 263 NE1 
441 1 Y 1 A TRP 263 ? CE2 ? A TRP 263 CE2 
442 1 Y 1 A TRP 263 ? CE3 ? A TRP 263 CE3 
443 1 Y 1 A TRP 263 ? CZ2 ? A TRP 263 CZ2 
444 1 Y 1 A TRP 263 ? CZ3 ? A TRP 263 CZ3 
445 1 Y 1 A TRP 263 ? CH2 ? A TRP 263 CH2 
446 1 Y 1 A PHE 264 ? CG  ? A PHE 264 CG  
447 1 Y 1 A PHE 264 ? CD1 ? A PHE 264 CD1 
448 1 Y 1 A PHE 264 ? CD2 ? A PHE 264 CD2 
449 1 Y 1 A PHE 264 ? CE1 ? A PHE 264 CE1 
450 1 Y 1 A PHE 264 ? CE2 ? A PHE 264 CE2 
451 1 Y 1 A PHE 264 ? CZ  ? A PHE 264 CZ  
452 1 Y 1 A GLN 266 ? CG  ? A GLN 266 CG  
453 1 Y 1 A GLN 266 ? CD  ? A GLN 266 CD  
454 1 Y 1 A GLN 266 ? OE1 ? A GLN 266 OE1 
455 1 Y 1 A GLN 266 ? NE2 ? A GLN 266 NE2 
456 1 Y 1 A LEU 267 ? CG  ? A LEU 267 CG  
457 1 Y 1 A LEU 267 ? CD1 ? A LEU 267 CD1 
458 1 Y 1 A LEU 267 ? CD2 ? A LEU 267 CD2 
459 1 Y 1 A ARG 270 ? CG  ? A ARG 270 CG  
460 1 Y 1 A ARG 270 ? CD  ? A ARG 270 CD  
461 1 Y 1 A ARG 270 ? NE  ? A ARG 270 NE  
462 1 Y 1 A ARG 270 ? CZ  ? A ARG 270 CZ  
463 1 Y 1 A ARG 270 ? NH1 ? A ARG 270 NH1 
464 1 Y 1 A ARG 270 ? NH2 ? A ARG 270 NH2 
465 1 Y 1 A VAL 271 ? CG1 ? A VAL 271 CG1 
466 1 Y 1 A VAL 271 ? CG2 ? A VAL 271 CG2 
467 1 Y 1 A SER 272 ? OG  ? A SER 272 OG  
468 1 Y 1 A GLU 273 ? CG  ? A GLU 273 CG  
469 1 Y 1 A GLU 273 ? CD  ? A GLU 273 CD  
470 1 Y 1 A GLU 273 ? OE1 ? A GLU 273 OE1 
471 1 Y 1 A GLU 273 ? OE2 ? A GLU 273 OE2 
472 1 Y 1 A GLN 274 ? CG  ? A GLN 274 CG  
473 1 Y 1 A GLN 274 ? CD  ? A GLN 274 CD  
474 1 Y 1 A GLN 274 ? OE1 ? A GLN 274 OE1 
475 1 Y 1 A GLN 274 ? NE2 ? A GLN 274 NE2 
476 1 Y 1 A GLU 275 ? CG  ? A GLU 275 CG  
477 1 Y 1 A GLU 275 ? CD  ? A GLU 275 CD  
478 1 Y 1 A GLU 275 ? OE1 ? A GLU 275 OE1 
479 1 Y 1 A GLU 275 ? OE2 ? A GLU 275 OE2 
480 1 Y 1 A SER 276 ? OG  ? A SER 276 OG  
481 1 Y 1 A GLU 277 ? CG  ? A GLU 277 CG  
482 1 Y 1 A GLU 277 ? CD  ? A GLU 277 CD  
483 1 Y 1 A GLU 277 ? OE1 ? A GLU 277 OE1 
484 1 Y 1 A GLU 277 ? OE2 ? A GLU 277 OE2 
485 1 Y 1 A LYS 394 ? CG  ? A LYS 394 CG  
486 1 Y 1 A LYS 394 ? CD  ? A LYS 394 CD  
487 1 Y 1 A LYS 394 ? CE  ? A LYS 394 CE  
488 1 Y 1 A LYS 394 ? NZ  ? A LYS 394 NZ  
489 1 Y 1 A ASN 406 ? CG  ? A ASN 406 CG  
490 1 Y 1 A ASN 406 ? OD1 ? A ASN 406 OD1 
491 1 Y 1 A ASN 406 ? ND2 ? A ASN 406 ND2 
492 1 Y 1 A TYR 409 ? CG  ? A TYR 409 CG  
493 1 Y 1 A TYR 409 ? CD1 ? A TYR 409 CD1 
494 1 Y 1 A TYR 409 ? CD2 ? A TYR 409 CD2 
495 1 Y 1 A TYR 409 ? CE1 ? A TYR 409 CE1 
496 1 Y 1 A TYR 409 ? CE2 ? A TYR 409 CE2 
497 1 Y 1 A TYR 409 ? CZ  ? A TYR 409 CZ  
498 1 Y 1 A TYR 409 ? OH  ? A TYR 409 OH  
499 1 Y 1 A THR 425 ? OG1 ? A THR 425 OG1 
500 1 Y 1 A THR 425 ? CG2 ? A THR 425 CG2 
501 1 Y 1 A ASP 426 ? CG  ? A ASP 426 CG  
502 1 Y 1 A ASP 426 ? OD1 ? A ASP 426 OD1 
503 1 Y 1 A ASP 426 ? OD2 ? A ASP 426 OD2 
504 1 Y 1 A GLU 427 ? CG  ? A GLU 427 CG  
505 1 Y 1 A GLU 427 ? CD  ? A GLU 427 CD  
506 1 Y 1 A GLU 427 ? OE1 ? A GLU 427 OE1 
507 1 Y 1 A GLU 427 ? OE2 ? A GLU 427 OE2 
508 1 Y 1 A GLU 428 ? CG  ? A GLU 428 CG  
509 1 Y 1 A GLU 428 ? CD  ? A GLU 428 CD  
510 1 Y 1 A GLU 428 ? OE1 ? A GLU 428 OE1 
511 1 Y 1 A GLU 428 ? OE2 ? A GLU 428 OE2 
512 1 Y 1 A SER 429 ? OG  ? A SER 429 OG  
513 1 Y 1 A ARG 431 ? CG  ? A ARG 431 CG  
514 1 Y 1 A ARG 431 ? CD  ? A ARG 431 CD  
515 1 Y 1 A ARG 431 ? NE  ? A ARG 431 NE  
516 1 Y 1 A ARG 431 ? CZ  ? A ARG 431 CZ  
517 1 Y 1 A ARG 431 ? NH1 ? A ARG 431 NH1 
518 1 Y 1 A ARG 431 ? NH2 ? A ARG 431 NH2 
519 1 Y 1 A SER 432 ? OG  ? A SER 432 OG  
520 1 Y 1 A LEU 433 ? CG  ? A LEU 433 CG  
521 1 Y 1 A LEU 433 ? CD1 ? A LEU 433 CD1 
522 1 Y 1 A LEU 433 ? CD2 ? A LEU 433 CD2 
523 1 Y 1 A SER 435 ? OG  ? A SER 435 OG  
524 1 Y 1 A GLN 438 ? CG  ? A GLN 438 CG  
525 1 Y 1 A GLN 438 ? CD  ? A GLN 438 CD  
526 1 Y 1 A GLN 438 ? OE1 ? A GLN 438 OE1 
527 1 Y 1 A GLN 438 ? NE2 ? A GLN 438 NE2 
528 1 Y 1 A LYS 439 ? CG  ? A LYS 439 CG  
529 1 Y 1 A LYS 439 ? CD  ? A LYS 439 CD  
530 1 Y 1 A LYS 439 ? CE  ? A LYS 439 CE  
531 1 Y 1 A LYS 439 ? NZ  ? A LYS 439 NZ  
532 1 Y 1 A ILE 440 ? CG1 ? A ILE 440 CG1 
533 1 Y 1 A ILE 440 ? CG2 ? A ILE 440 CG2 
534 1 Y 1 A ILE 440 ? CD1 ? A ILE 440 CD1 
535 1 Y 1 A ASP 441 ? CG  ? A ASP 441 CG  
536 1 Y 1 A ASP 441 ? OD1 ? A ASP 441 OD1 
537 1 Y 1 A ASP 441 ? OD2 ? A ASP 441 OD2 
538 1 Y 1 A GLU 442 ? CG  ? A GLU 442 CG  
539 1 Y 1 A GLU 442 ? CD  ? A GLU 442 CD  
540 1 Y 1 A GLU 442 ? OE1 ? A GLU 442 OE1 
541 1 Y 1 A GLU 442 ? OE2 ? A GLU 442 OE2 
542 1 Y 1 A ILE 443 ? CG1 ? A ILE 443 CG1 
543 1 Y 1 A ILE 443 ? CG2 ? A ILE 443 CG2 
544 1 Y 1 A ILE 443 ? CD1 ? A ILE 443 CD1 
545 1 Y 1 A ASP 446 ? CG  ? A ASP 446 CG  
546 1 Y 1 A ASP 446 ? OD1 ? A ASP 446 OD1 
547 1 Y 1 A ASP 446 ? OD2 ? A ASP 446 OD2 
548 1 Y 1 A PHE 447 ? CG  ? A PHE 447 CG  
549 1 Y 1 A PHE 447 ? CD1 ? A PHE 447 CD1 
550 1 Y 1 A PHE 447 ? CD2 ? A PHE 447 CD2 
551 1 Y 1 A PHE 447 ? CE1 ? A PHE 447 CE1 
552 1 Y 1 A PHE 447 ? CE2 ? A PHE 447 CE2 
553 1 Y 1 A PHE 447 ? CZ  ? A PHE 447 CZ  
554 1 Y 1 A GLU 448 ? CG  ? A GLU 448 CG  
555 1 Y 1 A GLU 448 ? CD  ? A GLU 448 CD  
556 1 Y 1 A GLU 448 ? OE1 ? A GLU 448 OE1 
557 1 Y 1 A GLU 448 ? OE2 ? A GLU 448 OE2 
558 1 Y 1 A ARG 449 ? CG  ? A ARG 449 CG  
559 1 Y 1 A ARG 449 ? CD  ? A ARG 449 CD  
560 1 Y 1 A ARG 449 ? NE  ? A ARG 449 NE  
561 1 Y 1 A ARG 449 ? CZ  ? A ARG 449 CZ  
562 1 Y 1 A ARG 449 ? NH1 ? A ARG 449 NH1 
563 1 Y 1 A ARG 449 ? NH2 ? A ARG 449 NH2 
564 1 Y 1 A ARG 450 ? CG  ? A ARG 450 CG  
565 1 Y 1 A ARG 450 ? CD  ? A ARG 450 CD  
566 1 Y 1 A ARG 450 ? NE  ? A ARG 450 NE  
567 1 Y 1 A ARG 450 ? CZ  ? A ARG 450 CZ  
568 1 Y 1 A ARG 450 ? NH1 ? A ARG 450 NH1 
569 1 Y 1 A ARG 450 ? NH2 ? A ARG 450 NH2 
570 1 Y 1 A ARG 451 ? CG  ? A ARG 451 CG  
571 1 Y 1 A ARG 451 ? CD  ? A ARG 451 CD  
572 1 Y 1 A ARG 451 ? NE  ? A ARG 451 NE  
573 1 Y 1 A ARG 451 ? CZ  ? A ARG 451 CZ  
574 1 Y 1 A ARG 451 ? NH1 ? A ARG 451 NH1 
575 1 Y 1 A ARG 451 ? NH2 ? A ARG 451 NH2 
576 1 Y 1 A MET 452 ? CG  ? A MET 452 CG  
577 1 Y 1 A MET 452 ? SD  ? A MET 452 SD  
578 1 Y 1 A MET 452 ? CE  ? A MET 452 CE  
579 1 Y 1 A SER 453 ? OG  ? A SER 453 OG  
580 1 Y 1 A VAL 454 ? CG1 ? A VAL 454 CG1 
581 1 Y 1 A VAL 454 ? CG2 ? A VAL 454 CG2 
582 1 Y 1 A VAL 455 ? CG1 ? A VAL 455 CG1 
583 1 Y 1 A VAL 455 ? CG2 ? A VAL 455 CG2 
584 1 Y 1 A VAL 456 ? CG1 ? A VAL 456 CG1 
585 1 Y 1 A VAL 456 ? CG2 ? A VAL 456 CG2 
586 1 Y 1 A GLU 458 ? CG  ? A GLU 458 CG  
587 1 Y 1 A GLU 458 ? CD  ? A GLU 458 CD  
588 1 Y 1 A GLU 458 ? OE1 ? A GLU 458 OE1 
589 1 Y 1 A GLU 458 ? OE2 ? A GLU 458 OE2 
590 1 Y 1 A ASN 459 ? CG  ? A ASN 459 CG  
591 1 Y 1 A ASN 459 ? OD1 ? A ASN 459 OD1 
592 1 Y 1 A ASN 459 ? ND2 ? A ASN 459 ND2 
593 1 Y 1 A THR 460 ? OG1 ? A THR 460 OG1 
594 1 Y 1 A THR 460 ? CG2 ? A THR 460 CG2 
595 1 Y 1 A GLU 461 ? CG  ? A GLU 461 CG  
596 1 Y 1 A GLU 461 ? CD  ? A GLU 461 CD  
597 1 Y 1 A GLU 461 ? OE1 ? A GLU 461 OE1 
598 1 Y 1 A GLU 461 ? OE2 ? A GLU 461 OE2 
599 1 Y 1 A HIS 462 ? CG  ? A HIS 462 CG  
600 1 Y 1 A HIS 462 ? ND1 ? A HIS 462 ND1 
601 1 Y 1 A HIS 462 ? CD2 ? A HIS 462 CD2 
602 1 Y 1 A HIS 462 ? CE1 ? A HIS 462 CE1 
603 1 Y 1 A HIS 462 ? NE2 ? A HIS 462 NE2 
604 1 Y 1 A HIS 463 ? CG  ? A HIS 463 CG  
605 1 Y 1 A HIS 463 ? ND1 ? A HIS 463 ND1 
606 1 Y 1 A HIS 463 ? CD2 ? A HIS 463 CD2 
607 1 Y 1 A HIS 463 ? CE1 ? A HIS 463 CE1 
608 1 Y 1 A HIS 463 ? NE2 ? A HIS 463 NE2 
609 1 Y 1 A GLN 464 ? CG  ? A GLN 464 CG  
610 1 Y 1 A GLN 464 ? CD  ? A GLN 464 CD  
611 1 Y 1 A GLN 464 ? OE1 ? A GLN 464 OE1 
612 1 Y 1 A GLN 464 ? NE2 ? A GLN 464 NE2 
613 1 Y 1 A LEU 465 ? CG  ? A LEU 465 CG  
614 1 Y 1 A LEU 465 ? CD1 ? A LEU 465 CD1 
615 1 Y 1 A LEU 465 ? CD2 ? A LEU 465 CD2 
616 1 Y 1 A LEU 520 ? CG  ? A LEU 520 CG  
617 1 Y 1 A LEU 520 ? CD1 ? A LEU 520 CD1 
618 1 Y 1 A LEU 520 ? CD2 ? A LEU 520 CD2 
619 1 Y 1 A ARG 523 ? CG  ? A ARG 523 CG  
620 1 Y 1 A ARG 523 ? CD  ? A ARG 523 CD  
621 1 Y 1 A ARG 523 ? NE  ? A ARG 523 NE  
622 1 Y 1 A ARG 523 ? CZ  ? A ARG 523 CZ  
623 1 Y 1 A ARG 523 ? NH1 ? A ARG 523 NH1 
624 1 Y 1 A ARG 523 ? NH2 ? A ARG 523 NH2 
625 1 Y 1 A GLU 524 ? CG  ? A GLU 524 CG  
626 1 Y 1 A GLU 524 ? CD  ? A GLU 524 CD  
627 1 Y 1 A GLU 524 ? OE1 ? A GLU 524 OE1 
628 1 Y 1 A GLU 524 ? OE2 ? A GLU 524 OE2 
629 1 Y 1 A ASP 526 ? CG  ? A ASP 526 CG  
630 1 Y 1 A ASP 526 ? OD1 ? A ASP 526 OD1 
631 1 Y 1 A ASP 526 ? OD2 ? A ASP 526 OD2 
632 1 Y 1 A TYR 527 ? CG  ? A TYR 527 CG  
633 1 Y 1 A TYR 527 ? CD1 ? A TYR 527 CD1 
634 1 Y 1 A TYR 527 ? CD2 ? A TYR 527 CD2 
635 1 Y 1 A TYR 527 ? CE1 ? A TYR 527 CE1 
636 1 Y 1 A TYR 527 ? CE2 ? A TYR 527 CE2 
637 1 Y 1 A TYR 527 ? CZ  ? A TYR 527 CZ  
638 1 Y 1 A TYR 527 ? OH  ? A TYR 527 OH  
639 1 Y 1 A GLN 528 ? CG  ? A GLN 528 CG  
640 1 Y 1 A GLN 528 ? CD  ? A GLN 528 CD  
641 1 Y 1 A GLN 528 ? OE1 ? A GLN 528 OE1 
642 1 Y 1 A GLN 528 ? NE2 ? A GLN 528 NE2 
643 1 Y 1 A ARG 529 ? CG  ? A ARG 529 CG  
644 1 Y 1 A ARG 529 ? CD  ? A ARG 529 CD  
645 1 Y 1 A ARG 529 ? NE  ? A ARG 529 NE  
646 1 Y 1 A ARG 529 ? CZ  ? A ARG 529 CZ  
647 1 Y 1 A ARG 529 ? NH1 ? A ARG 529 NH1 
648 1 Y 1 A ARG 529 ? NH2 ? A ARG 529 NH2 
649 1 Y 1 A ASP 531 ? CG  ? A ASP 531 CG  
650 1 Y 1 A ASP 531 ? OD1 ? A ASP 531 OD1 
651 1 Y 1 A ASP 531 ? OD2 ? A ASP 531 OD2 
652 1 Y 1 A GLU 532 ? CG  ? A GLU 532 CG  
653 1 Y 1 A GLU 532 ? CD  ? A GLU 532 CD  
654 1 Y 1 A GLU 532 ? OE1 ? A GLU 532 OE1 
655 1 Y 1 A GLU 532 ? OE2 ? A GLU 532 OE2 
656 1 Y 1 A SER 533 ? OG  ? A SER 533 OG  
657 1 Y 1 A ASP 534 ? CG  ? A ASP 534 CG  
658 1 Y 1 A ASP 534 ? OD1 ? A ASP 534 OD1 
659 1 Y 1 A ASP 534 ? OD2 ? A ASP 534 OD2 
660 1 Y 1 A LEU 535 ? CG  ? A LEU 535 CG  
661 1 Y 1 A LEU 535 ? CD1 ? A LEU 535 CD1 
662 1 Y 1 A LEU 535 ? CD2 ? A LEU 535 CD2 
663 1 Y 1 A ILE 536 ? CG1 ? A ILE 536 CG1 
664 1 Y 1 A ILE 536 ? CG2 ? A ILE 536 CG2 
665 1 Y 1 A ILE 536 ? CD1 ? A ILE 536 CD1 
666 1 Y 1 A LEU 537 ? CG  ? A LEU 537 CG  
667 1 Y 1 A LEU 537 ? CD1 ? A LEU 537 CD1 
668 1 Y 1 A LEU 537 ? CD2 ? A LEU 537 CD2 
669 1 Y 1 A GLU 538 ? CG  ? A GLU 538 CG  
670 1 Y 1 A GLU 538 ? CD  ? A GLU 538 CD  
671 1 Y 1 A GLU 538 ? OE1 ? A GLU 538 OE1 
672 1 Y 1 A GLU 538 ? OE2 ? A GLU 538 OE2 
673 1 Y 1 A TYR 540 ? CG  ? A TYR 540 CG  
674 1 Y 1 A TYR 540 ? CD1 ? A TYR 540 CD1 
675 1 Y 1 A TYR 540 ? CD2 ? A TYR 540 CD2 
676 1 Y 1 A TYR 540 ? CE1 ? A TYR 540 CE1 
677 1 Y 1 A TYR 540 ? CE2 ? A TYR 540 CE2 
678 1 Y 1 A TYR 540 ? CZ  ? A TYR 540 CZ  
679 1 Y 1 A TYR 540 ? OH  ? A TYR 540 OH  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UY9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UY9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UY9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8UY9 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 6722 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.571 ? 9160 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.189 ? 906  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.040 ? 1092 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1165 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8UY9 
_struct.title                        'Magnesium transporter MgtA monomer from E. coli in 5 mM MgCl2' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UY9 
_struct_keywords.text            
'magnesium, transport, membrane protein, dimer, oligomer, cryo-EM, P-type ATPase, ion translocation' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    ATMA_ECOLI 
_struct_ref.pdbx_db_accession          P0ABB8 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLKMAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENK
LPAQQPSPWWVHLWVCYRNPFNILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLPVEKAATTRQPEHSNPLECDTLC
FMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQESEPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALF
ALSVAVGLTPEMLPMIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDISGKTSERVL
HSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERRRMSVVVAENTEHHQLVCKGALQEILNVCSQ
VRHNGEIVPLDDIMLRKIKRVTDTLNRQGLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKA
SGITVKILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKERIVTLLKREGHVVGFMG
DGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLEEGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFL
PFLPMLPLHLLIQNLLYDVSQVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPETQT
LFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPLASYLQLQALPLSYFPWLVAILAGY
MTLTQLVKGFYSRRYGWQ
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8UY9 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 898 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P0ABB8 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  898 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       898 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UY9 HIS A 899 ? UNP P0ABB8 ? ? 'expression tag' 899 1 
1 8UY9 HIS A 900 ? UNP P0ABB8 ? ? 'expression tag' 900 2 
1 8UY9 HIS A 901 ? UNP P0ABB8 ? ? 'expression tag' 901 3 
1 8UY9 HIS A 902 ? UNP P0ABB8 ? ? 'expression tag' 902 4 
1 8UY9 HIS A 903 ? UNP P0ABB8 ? ? 'expression tag' 903 5 
1 8UY9 HIS A 904 ? UNP P0ABB8 ? ? 'expression tag' 904 6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 37  ? MET A 48  ? SER A 37  MET A 48  1 ? 12 
HELX_P HELX_P2  AA2 GLU A 52  ? PHE A 57  ? GLU A 52  PHE A 57  1 ? 6  
HELX_P HELX_P3  AA3 ASN A 65  ? GLY A 77  ? ASN A 65  GLY A 77  1 ? 13 
HELX_P HELX_P4  AA4 PRO A 88  ? CYS A 96  ? PRO A 88  CYS A 96  1 ? 9  
HELX_P HELX_P5  AA5 ASN A 99  ? THR A 115 ? ASN A 99  THR A 115 1 ? 17 
HELX_P HELX_P6  AA6 ASP A 117 ? ALA A 146 ? ASP A 117 ALA A 146 1 ? 30 
HELX_P HELX_P7  AA7 ASP A 177 ? LEU A 179 ? ASP A 177 LEU A 179 5 ? 3  
HELX_P HELX_P8  AA8 THR A 258 ? THR A 262 ? THR A 258 THR A 262 5 ? 5  
HELX_P HELX_P9  AA9 ASN A 279 ? THR A 310 ? ASN A 279 THR A 310 1 ? 32 
HELX_P HELX_P10 AB1 ASP A 313 ? LEU A 328 ? ASP A 313 LEU A 328 1 ? 16 
HELX_P HELX_P11 AB2 MET A 332 ? LYS A 350 ? MET A 332 LYS A 350 1 ? 19 
HELX_P HELX_P12 AB3 HIS A 357 ? MET A 367 ? HIS A 357 MET A 367 1 ? 11 
HELX_P HELX_P13 AB4 GLU A 397 ? TYR A 409 ? GLU A 397 TYR A 409 1 ? 13 
HELX_P HELX_P14 AB5 ASN A 415 ? THR A 425 ? ASN A 415 THR A 425 1 ? 11 
HELX_P HELX_P15 AB6 ASP A 426 ? TRP A 437 ? ASP A 426 TRP A 437 1 ? 12 
HELX_P HELX_P16 AB7 ALA A 470 ? VAL A 477 ? ALA A 470 VAL A 477 1 ? 8  
HELX_P HELX_P17 AB8 ASP A 491 ? GLY A 509 ? ASP A 491 GLY A 509 1 ? 19 
HELX_P HELX_P18 AB9 GLN A 528 ? GLU A 532 ? GLN A 528 GLU A 532 5 ? 5  
HELX_P HELX_P19 AC1 THR A 550 ? SER A 561 ? THR A 550 SER A 561 1 ? 12 
HELX_P HELX_P20 AC2 SER A 572 ? GLY A 584 ? SER A 572 GLY A 584 1 ? 13 
HELX_P HELX_P21 AC3 GLY A 593 ? LEU A 599 ? GLY A 593 LEU A 599 1 ? 7  
HELX_P HELX_P22 AC4 SER A 600 ? ARG A 610 ? SER A 600 ARG A 610 1 ? 11 
HELX_P HELX_P23 AC5 THR A 618 ? LYS A 630 ? THR A 618 LYS A 630 1 ? 13 
HELX_P HELX_P24 AC6 GLY A 642 ? ASN A 644 ? GLY A 642 ASN A 644 5 ? 3  
HELX_P HELX_P25 AC7 ASP A 645 ? ALA A 652 ? ASP A 645 ALA A 652 1 ? 8  
HELX_P HELX_P26 AC8 VAL A 662 ? ALA A 668 ? VAL A 662 ALA A 668 1 ? 7  
HELX_P HELX_P27 AC9 SER A 677 ? ALA A 716 ? SER A 677 ALA A 716 1 ? 40 
HELX_P HELX_P28 AD1 LEU A 726 ? GLN A 741 ? LEU A 726 GLN A 741 1 ? 16 
HELX_P HELX_P29 AD2 VAL A 742 ? ASP A 747 ? VAL A 742 ASP A 747 5 ? 6  
HELX_P HELX_P30 AD3 GLU A 752 ? LYS A 756 ? GLU A 752 LYS A 756 5 ? 5  
HELX_P HELX_P31 AD4 ASN A 761 ? VAL A 790 ? ASN A 761 VAL A 790 1 ? 30 
HELX_P HELX_P32 AD5 THR A 795 ? GLU A 797 ? THR A 795 GLU A 797 5 ? 3  
HELX_P HELX_P33 AD6 THR A 798 ? ARG A 822 ? THR A 798 ARG A 822 1 ? 25 
HELX_P HELX_P34 AD7 SER A 834 ? LEU A 851 ? SER A 834 LEU A 851 1 ? 18 
HELX_P HELX_P35 AD8 PRO A 855 ? LEU A 860 ? PRO A 855 LEU A 860 1 ? 6  
HELX_P HELX_P36 AD9 SER A 868 ? GLY A 889 ? SER A 868 GLY A 889 1 ? 22 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            metalc1 
_struct_conn.conn_type_id                  metalc 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           A 
_struct_conn.ptnr1_label_comp_id           ASN 
_struct_conn.ptnr1_label_seq_id            709 
_struct_conn.ptnr1_label_atom_id           OD1 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           MG 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           MG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            A 
_struct_conn.ptnr1_auth_comp_id            ASN 
_struct_conn.ptnr1_auth_seq_id             709 
_struct_conn.ptnr2_auth_asym_id            A 
_struct_conn.ptnr2_auth_comp_id            MG 
_struct_conn.ptnr2_auth_seq_id             1001 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               1.921 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 8 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
AA4 6 7 ? parallel      
AA4 7 8 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 THR A 156 ? VAL A 159 ? THR A 156 VAL A 159 
AA1 2 LEU A 172 ? PRO A 175 ? LEU A 172 PRO A 175 
AA2 1 ILE A 184 ? LEU A 187 ? ILE A 184 LEU A 187 
AA2 2 THR A 245 ? VAL A 255 ? THR A 245 VAL A 255 
AA2 3 LEU A 197 ? ALA A 208 ? LEU A 197 ALA A 208 
AA2 4 VAL A 219 ? LYS A 221 ? VAL A 219 LYS A 221 
AA3 1 ILE A 184 ? LEU A 187 ? ILE A 184 LEU A 187 
AA3 2 THR A 245 ? VAL A 255 ? THR A 245 VAL A 255 
AA3 3 LEU A 197 ? ALA A 208 ? LEU A 197 ALA A 208 
AA3 4 LEU A 239 ? CYS A 240 ? LEU A 239 CYS A 240 
AA4 1 VAL A 353 ? VAL A 355 ? VAL A 353 VAL A 355 
AA4 2 ILE A 671 ? LEU A 673 ? ILE A 671 LEU A 673 
AA4 3 ILE A 654 ? VAL A 658 ? ILE A 654 VAL A 658 
AA4 4 VAL A 636 ? MET A 639 ? VAL A 636 MET A 639 
AA4 5 ILE A 369 ? THR A 372 ? ILE A 369 THR A 372 
AA4 6 THR A 564 ? THR A 569 ? THR A 564 THR A 569 
AA4 7 LEU A 613 ? ALA A 615 ? LEU A 613 ALA A 615 
AA4 8 VAL A 591 ? ILE A 592 ? VAL A 591 ILE A 592 
AA5 1 VAL A 384 ? THR A 389 ? VAL A 384 THR A 389 
AA5 2 LEU A 535 ? LEU A 544 ? LEU A 535 LEU A 544 
AA5 3 ARG A 511 ? PRO A 521 ? ARG A 511 PRO A 521 
AA5 4 HIS A 462 ? GLY A 469 ? HIS A 462 GLY A 469 
AA5 5 ARG A 451 ? ALA A 457 ? ARG A 451 ALA A 457 
AA5 6 GLN A 438 ? ASP A 446 ? GLN A 438 ASP A 446 
AA6 1 VAL A 384 ? THR A 389 ? VAL A 384 THR A 389 
AA6 2 LEU A 535 ? LEU A 544 ? LEU A 535 LEU A 544 
AA6 3 CYS A 478 ? HIS A 483 ? CYS A 478 HIS A 483 
AA6 4 GLU A 486 ? PRO A 489 ? GLU A 486 PRO A 489 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ALA A 157 ? N ALA A 157 O ILE A 174 ? O ILE A 174 
AA2 1 2 N LEU A 187 ? N LEU A 187 O ALA A 251 ? O ALA A 251 
AA2 2 3 O GLN A 252 ? O GLN A 252 N GLN A 201 ? N GLN A 201 
AA2 3 4 N LEU A 205 ? N LEU A 205 O LYS A 221 ? O LYS A 221 
AA3 1 2 N LEU A 187 ? N LEU A 187 O ALA A 251 ? O ALA A 251 
AA3 2 3 O GLN A 252 ? O GLN A 252 N GLN A 201 ? N GLN A 201 
AA3 3 4 N LEU A 197 ? N LEU A 197 O CYS A 240 ? O CYS A 240 
AA4 1 2 N ILE A 354 ? N ILE A 354 O ILE A 672 ? O ILE A 672 
AA4 2 3 O ILE A 671 ? O ILE A 671 N SER A 657 ? N SER A 657 
AA4 3 4 O ILE A 656 ? O ILE A 656 N PHE A 638 ? N PHE A 638 
AA4 4 5 O GLY A 637 ? O GLY A 637 N CYS A 371 ? N CYS A 371 
AA4 5 6 N LEU A 370 ? N LEU A 370 O LYS A 566 ? O LYS A 566 
AA4 6 7 N ILE A 567 ? N ILE A 567 O PHE A 614 ? O PHE A 614 
AA4 7 8 O ALA A 615 ? O ALA A 615 N VAL A 591 ? N VAL A 591 
AA5 1 2 N THR A 389 ? N THR A 389 O TYR A 540 ? O TYR A 540 
AA5 2 3 O ILE A 541 ? O ILE A 541 N VAL A 513 ? N VAL A 513 
AA5 3 4 O LEU A 520 ? O LEU A 520 N HIS A 463 ? N HIS A 463 
AA5 4 5 O GLN A 464 ? O GLN A 464 N VAL A 456 ? N VAL A 456 
AA5 5 6 O SER A 453 ? O SER A 453 N ILE A 443 ? N ILE A 443 
AA6 1 2 N THR A 389 ? N THR A 389 O TYR A 540 ? O TYR A 540 
AA6 2 3 O LEU A 537 ? O LEU A 537 N GLN A 480 ? N GLN A 480 
AA6 3 4 N HIS A 483 ? N HIS A 483 O GLU A 486 ? O GLU A 486 
# 
_pdbx_entry_details.entry_id                   8UY9 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 THR A 115 ? ? -90.70  50.43   
2  1 ARG A 161 ? ? 53.65   -159.34 
3  1 ASN A 169 ? ? 60.89   -161.48 
4  1 ARG A 270 ? ? -92.48  53.12   
5  1 THR A 329 ? ? -162.19 88.98   
6  1 MET A 332 ? ? -98.18  34.08   
7  1 ASN A 387 ? ? 81.57   153.72  
8  1 ILE A 440 ? ? -120.73 -57.11  
9  1 VAL A 826 ? ? -36.65  134.40  
10 1 SER A 831 ? ? -162.91 112.33  
11 1 LYS A 888 ? ? -37.62  -38.49  
# 
loop_
_em_3d_fitting.id 
_em_3d_fitting.entry_id 
_em_3d_fitting.method 
_em_3d_fitting.target_criteria 
_em_3d_fitting.details 
_em_3d_fitting.overall_b_value 
_em_3d_fitting.ref_space 
_em_3d_fitting.ref_protocol 
1 8UY9 ? ? ? ? REAL 'RIGID BODY FIT' 
2 8UY9 ? ? ? ? REAL 'FLEXIBLE FIT'   
3 8UY9 ? ? ? ? REAL 'FLEXIBLE FIT'   
# 
loop_
_em_3d_fitting_list.id 
_em_3d_fitting_list.3d_fitting_id 
_em_3d_fitting_list.pdb_entry_id 
_em_3d_fitting_list.pdb_chain_id 
_em_3d_fitting_list.pdb_chain_residue_range 
_em_3d_fitting_list.details 
_em_3d_fitting_list.chain_id 
_em_3d_fitting_list.chain_residue_range 
_em_3d_fitting_list.source_name 
_em_3d_fitting_list.type 
_em_3d_fitting_list.accession_code 
_em_3d_fitting_list.initial_refinement_model_id 
1 1 . . . 'a monomer from our dimer MgtA structure' ? ? Other 'experimental model' ? ? 
2 2 . . . 'a monomer from our dimer MgtA structure' ? ? Other other                ? ? 
3 3 . . . 'a monomer from our dimer MgtA structure' ? ? Other 'experimental model' ? ? 
# 
_em_3d_reconstruction.entry_id                    8UY9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.65 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               78231 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '50 mM Tris/HCl, 50 mM K2SO4, 5 mM MgCl2, 0.007% glycol-diosgenin, 2 mM DTT' 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 
'Magnesium transporter MgtA from Escherichia coli in the monomeric form in the presence of 5 mM MgCl2' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8UY9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        60241 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            100 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    COPPER 
_em_sample_support.grid_mesh_size   400 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8UY9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              88 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   278 
_em_vitrification.instrument            'LEICA EM GP' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UY9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A PHE 2   ? A PHE 2   
3  1 Y 1 A LYS 3   ? A LYS 3   
4  1 Y 1 A GLU 4   ? A GLU 4   
5  1 Y 1 A ILE 5   ? A ILE 5   
6  1 Y 1 A PHE 6   ? A PHE 6   
7  1 Y 1 A THR 7   ? A THR 7   
8  1 Y 1 A ARG 8   ? A ARG 8   
9  1 Y 1 A LEU 9   ? A LEU 9   
10 1 Y 1 A ILE 10  ? A ILE 10  
11 1 Y 1 A ARG 11  ? A ARG 11  
12 1 Y 1 A HIS 12  ? A HIS 12  
13 1 Y 1 A LEU 13  ? A LEU 13  
14 1 Y 1 A PRO 14  ? A PRO 14  
15 1 Y 1 A SER 15  ? A SER 15  
16 1 Y 1 A ARG 16  ? A ARG 16  
17 1 Y 1 A LEU 17  ? A LEU 17  
18 1 Y 1 A VAL 18  ? A VAL 18  
19 1 Y 1 A HIS 19  ? A HIS 19  
20 1 Y 1 A ARG 20  ? A ARG 20  
21 1 Y 1 A ASP 21  ? A ASP 21  
22 1 Y 1 A PRO 22  ? A PRO 22  
23 1 Y 1 A LEU 23  ? A LEU 23  
24 1 Y 1 A PRO 24  ? A PRO 24  
25 1 Y 1 A GLY 25  ? A GLY 25  
26 1 Y 1 A ALA 26  ? A ALA 26  
27 1 Y 1 A GLN 27  ? A GLN 27  
28 1 Y 1 A GLN 28  ? A GLN 28  
29 1 Y 1 A THR 29  ? A THR 29  
30 1 Y 1 A VAL 30  ? A VAL 30  
31 1 Y 1 A ASN 31  ? A ASN 31  
32 1 Y 1 A THR 32  ? A THR 32  
33 1 Y 1 A VAL 33  ? A VAL 33  
34 1 Y 1 A ARG 893 ? A ARG 893 
35 1 Y 1 A ARG 894 ? A ARG 894 
36 1 Y 1 A TYR 895 ? A TYR 895 
37 1 Y 1 A GLY 896 ? A GLY 896 
38 1 Y 1 A TRP 897 ? A TRP 897 
39 1 Y 1 A GLN 898 ? A GLN 898 
40 1 Y 1 A HIS 899 ? A HIS 899 
41 1 Y 1 A HIS 900 ? A HIS 900 
42 1 Y 1 A HIS 901 ? A HIS 901 
43 1 Y 1 A HIS 902 ? A HIS 902 
44 1 Y 1 A HIS 903 ? A HIS 903 
45 1 Y 1 A HIS 904 ? A HIS 904 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
MG  MG   MG N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-11-13 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UY9 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'Magnesium transporter MgtA monomer from E. coli in 5 mM MgCl2' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.1 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               'Escherichia coli K-12' 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              pETDuet-1 
_em_entity_assembly_recombinant.strain               'Escherichia coli C43 (DE3)' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               4.31 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             
;A first dataset was collected with a dose rate of 9.5 A/px/s (~7.5 on the camera through the sample), exposure time 0.0712 s/frame (~1 e-/A2) and total exposure time of 4.31 s per movie (~60 e-/A2), resulting in a total of 10,246 movies with 60 frames each. 
A second dataset was collected with a dose rate of 10 A/px/s (~7.5 on the camera through the sample), exposure time 0.0668 s/frame (~1 e-/A2) and total exposure time of 3.46 s per movie (~50 e-/A2), resulting in a total of 6906 movies with 50 frames each.
;
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    2 
_em_image_recording.num_real_images                     17152 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    20 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
_em_particle_selection.details                  
;1,578,214 particles were initially selected from dataset 1 (10,164 selected movies from 10,246 total).
1,775,726 particles were initially selected from dataset 2 (5,778 selected movies from 6,906 total).
;
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   3353940 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? cryoSPARC      ?           
'PARTICLE SELECTION'       ? 2  1 ? ? ?              ?           
'IMAGE ACQUISITION'        ? 3  ? ? 1 SerialEM       3.8-11      
MASKING                    ? 4  ? ? ? ?              ?           
'CTF CORRECTION'           ? 5  1 ? ? cryoSPARC      ?           
'LAYERLINE INDEXING'       ? 6  ? ? ? ?              ?           
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?              ?           
'MODEL FITTING'            ? 8  ? 1 ? 'UCSF Chimera' 8.6.10      
OTHER                      ? 9  ? ? ? ?              ?           
'IMAGE ACQUISITION'        ? 10 ? ? ? ?              ?           
'CTF CORRECTION'           ? 11 1 ? ? ?              ?           
'MODEL REFINEMENT'         ? 12 ? 1 ? ?              ?           
'MODEL FITTING'            ? 13 ? 2 ? Coot           0.9.8.7     
'MODEL REFINEMENT'         ? 14 ? 2 ? Coot           0.9.8.7     
'MODEL FITTING'            ? 15 ? 3 ? PHENIX         1.20.1-4487 
'MODEL REFINEMENT'         ? 16 ? 3 ? PHENIX         1.20.1-4487 
'INITIAL EULER ASSIGNMENT' ? 17 1 ? ? cryoSPARC      ?           
'INITIAL EULER ASSIGNMENT' ? 18 1 ? ? ?              ?           
'FINAL EULER ASSIGNMENT'   ? 19 1 ? ? cryoSPARC      ?           
'FINAL EULER ASSIGNMENT'   ? 20 1 ? ? ?              ?           
CLASSIFICATION             ? 21 1 ? ? cryoSPARC      ?           
CLASSIFICATION             ? 22 1 ? ? ?              ?           
RECONSTRUCTION             ? 23 1 ? ? cryoSPARC      ?           
RECONSTRUCTION             ? 24 1 ? ? ?              ?           
# 
_em_specimen.concentration           3.2 
_em_specimen.details                 'E. coli MgtA purified with a C-terminal His-tag' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008998'  1 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008855'  2 
'National Institutes of Health/Eunice Kennedy Shriver National Institute of Child Health & Human Development (NIH/NICHD)' 
'United States' 'ZIA HD008955'  3 
'National Institutes of Health/National Library of Medicine (NIH/NLM)'                                                    
'United States' LM594244        4 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)'                                
'United States' 1FI2GM146628-01 5 
'German Research Foundation (DFG)'                                                                                        Germany 
3542/1-1        6 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.entity_id_list 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
_pdbx_initial_refinement_model.details 
1 ? 'experimental model' Other ? ? 
2 ? other                Other ? ? 
# 
_atom_sites.entry_id                    8UY9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . VAL A 1 34  ? 147.029 128.867 118.961 1.00 236.94 ? 34   VAL A N   1 
ATOM   2    C  CA  . VAL A 1 34  ? 146.986 129.097 117.523 1.00 236.94 ? 34   VAL A CA  1 
ATOM   3    C  C   . VAL A 1 34  ? 146.131 128.035 116.844 1.00 236.94 ? 34   VAL A C   1 
ATOM   4    O  O   . VAL A 1 34  ? 146.324 126.840 117.067 1.00 236.94 ? 34   VAL A O   1 
ATOM   5    C  CB  . VAL A 1 34  ? 148.401 129.122 116.921 1.00 236.94 ? 34   VAL A CB  1 
ATOM   6    N  N   . PRO A 1 35  ? 145.187 128.468 116.014 1.00 238.14 ? 35   PRO A N   1 
ATOM   7    C  CA  . PRO A 1 35  ? 144.317 127.518 115.320 1.00 238.14 ? 35   PRO A CA  1 
ATOM   8    C  C   . PRO A 1 35  ? 144.977 126.999 114.056 1.00 238.14 ? 35   PRO A C   1 
ATOM   9    O  O   . PRO A 1 35  ? 145.581 127.773 113.297 1.00 238.14 ? 35   PRO A O   1 
ATOM   10   C  CB  . PRO A 1 35  ? 143.068 128.352 114.998 1.00 238.14 ? 35   PRO A CB  1 
ATOM   11   C  CG  . PRO A 1 35  ? 143.533 129.783 115.001 1.00 238.14 ? 35   PRO A CG  1 
ATOM   12   C  CD  . PRO A 1 35  ? 144.888 129.865 115.657 1.00 238.14 ? 35   PRO A CD  1 
ATOM   13   N  N   . PRO A 1 36  ? 144.895 125.691 113.802 1.00 239.42 ? 36   PRO A N   1 
ATOM   14   C  CA  . PRO A 1 36  ? 145.498 125.146 112.574 1.00 239.42 ? 36   PRO A CA  1 
ATOM   15   C  C   . PRO A 1 36  ? 144.901 125.717 111.301 1.00 239.42 ? 36   PRO A C   1 
ATOM   16   O  O   . PRO A 1 36  ? 145.608 125.825 110.291 1.00 239.42 ? 36   PRO A O   1 
ATOM   17   C  CB  . PRO A 1 36  ? 145.237 123.638 112.697 1.00 239.42 ? 36   PRO A CB  1 
ATOM   18   C  CG  . PRO A 1 36  ? 144.058 123.530 113.608 1.00 239.42 ? 36   PRO A CG  1 
ATOM   19   C  CD  . PRO A 1 36  ? 144.202 124.656 114.588 1.00 239.42 ? 36   PRO A CD  1 
ATOM   20   N  N   . SER A 1 37  ? 143.615 126.079 111.315 1.00 238.12 ? 37   SER A N   1 
ATOM   21   C  CA  . SER A 1 37  ? 142.995 126.657 110.127 1.00 238.12 ? 37   SER A CA  1 
ATOM   22   C  C   . SER A 1 37  ? 143.640 127.986 109.757 1.00 238.12 ? 37   SER A C   1 
ATOM   23   O  O   . SER A 1 37  ? 143.873 128.265 108.575 1.00 238.12 ? 37   SER A O   1 
ATOM   24   C  CB  . SER A 1 37  ? 141.493 126.832 110.351 1.00 238.12 ? 37   SER A CB  1 
ATOM   25   N  N   . LEU A 1 38  ? 143.938 128.821 110.755 1.00 236.21 ? 38   LEU A N   1 
ATOM   26   C  CA  . LEU A 1 38  ? 144.576 130.103 110.478 1.00 236.21 ? 38   LEU A CA  1 
ATOM   27   C  C   . LEU A 1 38  ? 146.056 129.940 110.158 1.00 236.21 ? 38   LEU A C   1 
ATOM   28   O  O   . LEU A 1 38  ? 146.691 130.884 109.674 1.00 236.21 ? 38   LEU A O   1 
ATOM   29   C  CB  . LEU A 1 38  ? 144.391 131.050 111.664 1.00 236.21 ? 38   LEU A CB  1 
ATOM   30   N  N   . SER A 1 39  ? 146.622 128.761 110.419 1.00 236.56 ? 39   SER A N   1 
ATOM   31   C  CA  . SER A 1 39  ? 148.028 128.491 110.156 1.00 236.56 ? 39   SER A CA  1 
ATOM   32   C  C   . SER A 1 39  ? 148.285 128.059 108.717 1.00 236.56 ? 39   SER A C   1 
ATOM   33   O  O   . SER A 1 39  ? 149.445 127.862 108.336 1.00 236.56 ? 39   SER A O   1 
ATOM   34   C  CB  . SER A 1 39  ? 148.548 127.427 111.125 1.00 236.56 ? 39   SER A CB  1 
ATOM   35   N  N   . ALA A 1 40  ? 147.235 127.912 107.912 1.00 237.98 ? 40   ALA A N   1 
ATOM   36   C  CA  . ALA A 1 40  ? 147.369 127.534 106.513 1.00 237.98 ? 40   ALA A CA  1 
ATOM   37   C  C   . ALA A 1 40  ? 147.028 128.654 105.544 1.00 237.98 ? 40   ALA A C   1 
ATOM   38   O  O   . ALA A 1 40  ? 147.600 128.698 104.452 1.00 237.98 ? 40   ALA A O   1 
ATOM   39   C  CB  . ALA A 1 40  ? 146.483 126.319 106.197 1.00 237.98 ? 40   ALA A CB  1 
ATOM   40   N  N   . HIS A 1 41  ? 146.112 129.555 105.909 1.00 237.64 ? 41   HIS A N   1 
ATOM   41   C  CA  . HIS A 1 41  ? 145.790 130.679 105.037 1.00 237.64 ? 41   HIS A CA  1 
ATOM   42   C  C   . HIS A 1 41  ? 146.996 131.591 104.848 1.00 237.64 ? 41   HIS A C   1 
ATOM   43   O  O   . HIS A 1 41  ? 147.236 132.094 103.744 1.00 237.64 ? 41   HIS A O   1 
ATOM   44   C  CB  . HIS A 1 41  ? 144.607 131.463 105.606 1.00 237.64 ? 41   HIS A CB  1 
ATOM   45   N  N   . CYS A 1 42  ? 147.764 131.818 105.916 1.00 236.80 ? 42   CYS A N   1 
ATOM   46   C  CA  . CYS A 1 42  ? 148.962 132.643 105.804 1.00 236.80 ? 42   CYS A CA  1 
ATOM   47   C  C   . CYS A 1 42  ? 149.982 132.012 104.865 1.00 236.80 ? 42   CYS A C   1 
ATOM   48   O  O   . CYS A 1 42  ? 150.582 132.703 104.034 1.00 236.80 ? 42   CYS A O   1 
ATOM   49   C  CB  . CYS A 1 42  ? 149.574 132.869 107.187 1.00 236.80 ? 42   CYS A CB  1 
ATOM   50   N  N   . LEU A 1 43  ? 150.188 130.697 104.979 1.00 236.28 ? 43   LEU A N   1 
ATOM   51   C  CA  . LEU A 1 43  ? 151.118 130.015 104.085 1.00 236.28 ? 43   LEU A CA  1 
ATOM   52   C  C   . LEU A 1 43  ? 150.632 130.063 102.641 1.00 236.28 ? 43   LEU A C   1 
ATOM   53   O  O   . LEU A 1 43  ? 151.427 130.268 101.716 1.00 236.28 ? 43   LEU A O   1 
ATOM   54   C  CB  . LEU A 1 43  ? 151.316 128.568 104.538 1.00 236.28 ? 43   LEU A CB  1 
ATOM   55   N  N   . LYS A 1 44  ? 149.326 129.873 102.430 1.00 236.01 ? 44   LYS A N   1 
ATOM   56   C  CA  . LYS A 1 44  ? 148.778 129.938 101.079 1.00 236.01 ? 44   LYS A CA  1 
ATOM   57   C  C   . LYS A 1 44  ? 148.957 131.325 100.477 1.00 236.01 ? 44   LYS A C   1 
ATOM   58   O  O   . LYS A 1 44  ? 149.312 131.458 99.300  1.00 236.01 ? 44   LYS A O   1 
ATOM   59   C  CB  . LYS A 1 44  ? 147.301 129.544 101.093 1.00 236.01 ? 44   LYS A CB  1 
ATOM   60   N  N   . MET A 1 45  ? 148.714 132.373 101.270 1.00 235.55 ? 45   MET A N   1 
ATOM   61   C  CA  . MET A 1 45  ? 148.911 133.734 100.783 1.00 235.55 ? 45   MET A CA  1 
ATOM   62   C  C   . MET A 1 45  ? 150.380 134.024 100.501 1.00 235.55 ? 45   MET A C   1 
ATOM   63   O  O   . MET A 1 45  ? 150.697 134.712 99.524  1.00 235.55 ? 45   MET A O   1 
ATOM   64   C  CB  . MET A 1 45  ? 148.355 134.739 101.792 1.00 235.55 ? 45   MET A CB  1 
ATOM   65   N  N   . ALA A 1 46  ? 151.285 133.519 101.343 1.00 233.99 ? 46   ALA A N   1 
ATOM   66   C  CA  . ALA A 1 46  ? 152.711 133.716 101.108 1.00 233.99 ? 46   ALA A CA  1 
ATOM   67   C  C   . ALA A 1 46  ? 153.155 133.024 99.825  1.00 233.99 ? 46   ALA A C   1 
ATOM   68   O  O   . ALA A 1 46  ? 153.972 133.560 99.068  1.00 233.99 ? 46   ALA A O   1 
ATOM   69   C  CB  . ALA A 1 46  ? 153.516 133.208 102.304 1.00 233.99 ? 46   ALA A CB  1 
ATOM   70   N  N   . VAL A 1 47  ? 152.624 131.827 99.563  1.00 232.11 ? 47   VAL A N   1 
ATOM   71   C  CA  . VAL A 1 47  ? 152.961 131.090 98.349  1.00 232.11 ? 47   VAL A CA  1 
ATOM   72   C  C   . VAL A 1 47  ? 152.102 131.492 97.158  1.00 232.11 ? 47   VAL A C   1 
ATOM   73   O  O   . VAL A 1 47  ? 152.388 131.056 96.030  1.00 232.11 ? 47   VAL A O   1 
ATOM   74   C  CB  . VAL A 1 47  ? 152.854 129.566 98.573  1.00 232.11 ? 47   VAL A CB  1 
ATOM   75   N  N   . MET A 1 48  ? 151.065 132.300 97.364  1.00 229.34 ? 48   MET A N   1 
ATOM   76   C  CA  . MET A 1 48  ? 150.216 132.716 96.262  1.00 229.34 ? 48   MET A CA  1 
ATOM   77   C  C   . MET A 1 48  ? 150.955 133.699 95.355  1.00 229.34 ? 48   MET A C   1 
ATOM   78   O  O   . MET A 1 48  ? 151.730 134.534 95.830  1.00 229.34 ? 48   MET A O   1 
ATOM   79   C  CB  . MET A 1 48  ? 148.934 133.360 96.783  1.00 229.34 ? 48   MET A CB  1 
ATOM   80   N  N   . PRO A 1 49  ? 150.739 133.613 94.043  1.00 224.08 ? 49   PRO A N   1 
ATOM   81   C  CA  . PRO A 1 49  ? 151.349 134.587 93.132  1.00 224.08 ? 49   PRO A CA  1 
ATOM   82   C  C   . PRO A 1 49  ? 150.830 135.992 93.397  1.00 224.08 ? 49   PRO A C   1 
ATOM   83   O  O   . PRO A 1 49  ? 149.679 136.191 93.791  1.00 224.08 ? 49   PRO A O   1 
ATOM   84   C  CB  . PRO A 1 49  ? 150.930 134.088 91.743  1.00 224.08 ? 49   PRO A CB  1 
ATOM   85   C  CG  . PRO A 1 49  ? 150.593 132.643 91.940  1.00 224.08 ? 49   PRO A CG  1 
ATOM   86   C  CD  . PRO A 1 49  ? 150.019 132.552 93.320  1.00 224.08 ? 49   PRO A CD  1 
ATOM   87   N  N   . GLU A 1 50  ? 151.704 136.976 93.174  1.00 219.99 ? 50   GLU A N   1 
ATOM   88   C  CA  . GLU A 1 50  ? 151.318 138.367 93.388  1.00 219.99 ? 50   GLU A CA  1 
ATOM   89   C  C   . GLU A 1 50  ? 150.336 138.850 92.328  1.00 219.99 ? 50   GLU A C   1 
ATOM   90   O  O   . GLU A 1 50  ? 149.605 139.820 92.561  1.00 219.99 ? 50   GLU A O   1 
ATOM   91   C  CB  . GLU A 1 50  ? 152.558 139.259 93.408  1.00 219.99 ? 50   GLU A CB  1 
ATOM   92   N  N   . GLU A 1 51  ? 150.310 138.199 91.162  1.00 219.05 ? 51   GLU A N   1 
ATOM   93   C  CA  . GLU A 1 51  ? 149.399 138.614 90.100  1.00 219.05 ? 51   GLU A CA  1 
ATOM   94   C  C   . GLU A 1 51  ? 147.943 138.442 90.517  1.00 219.05 ? 51   GLU A C   1 
ATOM   95   O  O   . GLU A 1 51  ? 147.108 139.316 90.256  1.00 219.05 ? 51   GLU A O   1 
ATOM   96   C  CB  . GLU A 1 51  ? 149.688 137.824 88.823  1.00 219.05 ? 51   GLU A CB  1 
ATOM   97   N  N   . GLU A 1 52  ? 147.620 137.325 91.164  1.00 218.40 ? 52   GLU A N   1 
ATOM   98   C  CA  . GLU A 1 52  ? 146.257 137.042 91.592  1.00 218.40 ? 52   GLU A CA  1 
ATOM   99   C  C   . GLU A 1 52  ? 145.929 137.624 92.960  1.00 218.40 ? 52   GLU A C   1 
ATOM   100  O  O   . GLU A 1 52  ? 144.782 137.511 93.406  1.00 218.40 ? 52   GLU A O   1 
ATOM   101  C  CB  . GLU A 1 52  ? 146.014 135.529 91.608  1.00 218.40 ? 52   GLU A CB  1 
ATOM   102  N  N   . LEU A 1 53  ? 146.901 138.241 93.636  1.00 217.47 ? 53   LEU A N   1 
ATOM   103  C  CA  . LEU A 1 53  ? 146.637 138.811 94.953  1.00 217.47 ? 53   LEU A CA  1 
ATOM   104  C  C   . LEU A 1 53  ? 145.785 140.070 94.864  1.00 217.47 ? 53   LEU A C   1 
ATOM   105  O  O   . LEU A 1 53  ? 145.001 140.350 95.778  1.00 217.47 ? 53   LEU A O   1 
ATOM   106  C  CB  . LEU A 1 53  ? 147.954 139.111 95.668  1.00 217.47 ? 53   LEU A CB  1 
ATOM   107  N  N   . TRP A 1 54  ? 145.928 140.841 93.783  1.00 215.42 ? 54   TRP A N   1 
ATOM   108  C  CA  . TRP A 1 54  ? 145.155 142.071 93.642  1.00 215.42 ? 54   TRP A CA  1 
ATOM   109  C  C   . TRP A 1 54  ? 143.663 141.784 93.529  1.00 215.42 ? 54   TRP A C   1 
ATOM   110  O  O   . TRP A 1 54  ? 142.844 142.477 94.143  1.00 215.42 ? 54   TRP A O   1 
ATOM   111  C  CB  . TRP A 1 54  ? 145.644 142.859 92.426  1.00 215.42 ? 54   TRP A CB  1 
ATOM   112  N  N   . LYS A 1 55  ? 143.290 140.767 92.749  1.00 216.04 ? 55   LYS A N   1 
ATOM   113  C  CA  . LYS A 1 55  ? 141.879 140.449 92.566  1.00 216.04 ? 55   LYS A CA  1 
ATOM   114  C  C   . LYS A 1 55  ? 141.278 139.763 93.786  1.00 216.04 ? 55   LYS A C   1 
ATOM   115  O  O   . LYS A 1 55  ? 140.086 139.938 94.063  1.00 216.04 ? 55   LYS A O   1 
ATOM   116  C  CB  . LYS A 1 55  ? 141.695 139.567 91.329  1.00 216.04 ? 55   LYS A CB  1 
ATOM   117  N  N   . THR A 1 56  ? 142.076 138.980 94.516  1.00 215.17 ? 56   THR A N   1 
ATOM   118  C  CA  . THR A 1 56  ? 141.557 138.275 95.685  1.00 215.17 ? 56   THR A CA  1 
ATOM   119  C  C   . THR A 1 56  ? 141.099 139.249 96.764  1.00 215.17 ? 56   THR A C   1 
ATOM   120  O  O   . THR A 1 56  ? 140.042 139.058 97.376  1.00 215.17 ? 56   THR A O   1 
ATOM   121  C  CB  . THR A 1 56  ? 142.617 137.324 96.240  1.00 215.17 ? 56   THR A CB  1 
ATOM   122  N  N   . PHE A 1 57  ? 141.880 140.298 97.011  1.00 215.82 ? 57   PHE A N   1 
ATOM   123  C  CA  . PHE A 1 57  ? 141.567 141.285 98.035  1.00 215.82 ? 57   PHE A CA  1 
ATOM   124  C  C   . PHE A 1 57  ? 140.860 142.512 97.474  1.00 215.82 ? 57   PHE A C   1 
ATOM   125  O  O   . PHE A 1 57  ? 140.606 143.461 98.224  1.00 215.82 ? 57   PHE A O   1 
ATOM   126  C  CB  . PHE A 1 57  ? 142.843 141.705 98.767  1.00 215.82 ? 57   PHE A CB  1 
ATOM   127  N  N   . ASP A 1 58  ? 140.538 142.512 96.181  1.00 214.71 ? 58   ASP A N   1 
ATOM   128  C  CA  . ASP A 1 58  ? 139.886 143.639 95.513  1.00 214.71 ? 58   ASP A CA  1 
ATOM   129  C  C   . ASP A 1 58  ? 140.691 144.925 95.706  1.00 214.71 ? 58   ASP A C   1 
ATOM   130  O  O   . ASP A 1 58  ? 140.191 145.947 96.180  1.00 214.71 ? 58   ASP A O   1 
ATOM   131  C  CB  . ASP A 1 58  ? 138.445 143.807 96.004  1.00 214.71 ? 58   ASP A CB  1 
ATOM   132  C  CG  . ASP A 1 58  ? 137.560 142.635 95.628  1.00 214.71 ? 58   ASP A CG  1 
ATOM   133  O  OD1 . ASP A 1 58  ? 137.818 142.006 94.580  1.00 214.71 ? 58   ASP A OD1 1 
ATOM   134  O  OD2 . ASP A 1 58  ? 136.607 142.343 96.379  1.00 214.71 ? 58   ASP A OD2 1 
ATOM   135  N  N   . THR A 1 59  ? 141.964 144.852 95.324  1.00 215.81 ? 59   THR A N   1 
ATOM   136  C  CA  . THR A 1 59  ? 142.897 145.957 95.487  1.00 215.81 ? 59   THR A CA  1 
ATOM   137  C  C   . THR A 1 59  ? 143.537 146.291 94.149  1.00 215.81 ? 59   THR A C   1 
ATOM   138  O  O   . THR A 1 59  ? 143.781 145.402 93.327  1.00 215.81 ? 59   THR A O   1 
ATOM   139  C  CB  . THR A 1 59  ? 143.989 145.621 96.512  1.00 215.81 ? 59   THR A CB  1 
ATOM   140  N  N   . HIS A 1 60  ? 143.805 147.578 93.937  1.00 216.07 ? 60   HIS A N   1 
ATOM   141  C  CA  . HIS A 1 60  ? 144.438 148.060 92.723  1.00 216.07 ? 60   HIS A CA  1 
ATOM   142  C  C   . HIS A 1 60  ? 145.861 148.528 93.012  1.00 216.07 ? 60   HIS A C   1 
ATOM   143  O  O   . HIS A 1 60  ? 146.163 148.959 94.130  1.00 216.07 ? 60   HIS A O   1 
ATOM   144  C  CB  . HIS A 1 60  ? 143.641 149.215 92.104  1.00 216.07 ? 60   HIS A CB  1 
ATOM   145  N  N   . PRO A 1 61  ? 146.763 148.443 92.029  1.00 214.40 ? 61   PRO A N   1 
ATOM   146  C  CA  . PRO A 1 61  ? 148.134 148.931 92.254  1.00 214.40 ? 61   PRO A CA  1 
ATOM   147  C  C   . PRO A 1 61  ? 148.201 150.400 92.629  1.00 214.40 ? 61   PRO A C   1 
ATOM   148  O  O   . PRO A 1 61  ? 149.069 150.789 93.421  1.00 214.40 ? 61   PRO A O   1 
ATOM   149  C  CB  . PRO A 1 61  ? 148.825 148.660 90.910  1.00 214.40 ? 61   PRO A CB  1 
ATOM   150  C  CG  . PRO A 1 61  ? 148.041 147.549 90.298  1.00 214.40 ? 61   PRO A CG  1 
ATOM   151  C  CD  . PRO A 1 61  ? 146.619 147.761 90.731  1.00 214.40 ? 61   PRO A CD  1 
ATOM   152  N  N   . GLU A 1 62  ? 147.311 151.232 92.081  1.00 217.21 ? 62   GLU A N   1 
ATOM   153  C  CA  . GLU A 1 62  ? 147.304 152.647 92.438  1.00 217.21 ? 62   GLU A CA  1 
ATOM   154  C  C   . GLU A 1 62  ? 146.890 152.858 93.889  1.00 217.21 ? 62   GLU A C   1 
ATOM   155  O  O   . GLU A 1 62  ? 147.391 153.777 94.547  1.00 217.21 ? 62   GLU A O   1 
ATOM   156  C  CB  . GLU A 1 62  ? 146.376 153.421 91.503  1.00 217.21 ? 62   GLU A CB  1 
ATOM   157  N  N   . GLY A 1 63  ? 145.986 152.028 94.400  1.00 217.85 ? 63   GLY A N   1 
ATOM   158  C  CA  . GLY A 1 63  ? 145.532 152.150 95.771  1.00 217.85 ? 63   GLY A CA  1 
ATOM   159  C  C   . GLY A 1 63  ? 144.062 151.827 95.936  1.00 217.85 ? 63   GLY A C   1 
ATOM   160  O  O   . GLY A 1 63  ? 143.475 151.129 95.103  1.00 217.85 ? 63   GLY A O   1 
ATOM   161  N  N   . LEU A 1 64  ? 143.455 152.330 97.008  1.00 222.95 ? 64   LEU A N   1 
ATOM   162  C  CA  . LEU A 1 64  ? 142.043 152.110 97.287  1.00 222.95 ? 64   LEU A CA  1 
ATOM   163  C  C   . LEU A 1 64  ? 141.353 153.455 97.444  1.00 222.95 ? 64   LEU A C   1 
ATOM   164  O  O   . LEU A 1 64  ? 141.835 154.321 98.181  1.00 222.95 ? 64   LEU A O   1 
ATOM   165  C  CB  . LEU A 1 64  ? 141.851 151.263 98.549  1.00 222.95 ? 64   LEU A CB  1 
ATOM   166  N  N   . ASN A 1 65  ? 140.229 153.625 96.754  1.00 224.77 ? 65   ASN A N   1 
ATOM   167  C  CA  . ASN A 1 65  ? 139.472 154.864 96.827  1.00 224.77 ? 65   ASN A CA  1 
ATOM   168  C  C   . ASN A 1 65  ? 138.684 154.922 98.134  1.00 224.77 ? 65   ASN A C   1 
ATOM   169  O  O   . ASN A 1 65  ? 138.678 153.981 98.933  1.00 224.77 ? 65   ASN A O   1 
ATOM   170  C  CB  . ASN A 1 65  ? 138.549 154.993 95.618  1.00 224.77 ? 65   ASN A CB  1 
ATOM   171  N  N   . GLN A 1 66  ? 138.013 156.054 98.359  1.00 226.34 ? 66   GLN A N   1 
ATOM   172  C  CA  . GLN A 1 66  ? 137.208 156.206 99.567  1.00 226.34 ? 66   GLN A CA  1 
ATOM   173  C  C   . GLN A 1 66  ? 136.063 155.201 99.597  1.00 226.34 ? 66   GLN A C   1 
ATOM   174  O  O   . GLN A 1 66  ? 135.790 154.591 100.637 1.00 226.34 ? 66   GLN A O   1 
ATOM   175  C  CB  . GLN A 1 66  ? 136.672 157.634 99.665  1.00 226.34 ? 66   GLN A CB  1 
ATOM   176  N  N   . ALA A 1 67  ? 135.384 155.013 98.462  1.00 227.26 ? 67   ALA A N   1 
ATOM   177  C  CA  . ALA A 1 67  ? 134.292 154.047 98.405  1.00 227.26 ? 67   ALA A CA  1 
ATOM   178  C  C   . ALA A 1 67  ? 134.796 152.626 98.620  1.00 227.26 ? 67   ALA A C   1 
ATOM   179  O  O   . ALA A 1 67  ? 134.178 151.844 99.351  1.00 227.26 ? 67   ALA A O   1 
ATOM   180  C  CB  . ALA A 1 67  ? 133.558 154.162 97.069  1.00 227.26 ? 67   ALA A CB  1 
ATOM   181  N  N   . GLU A 1 68  ? 135.920 152.273 97.991  1.00 225.78 ? 68   GLU A N   1 
ATOM   182  C  CA  . GLU A 1 68  ? 136.475 150.933 98.154  1.00 225.78 ? 68   GLU A CA  1 
ATOM   183  C  C   . GLU A 1 68  ? 136.912 150.691 99.594  1.00 225.78 ? 68   GLU A C   1 
ATOM   184  O  O   . GLU A 1 68  ? 136.669 149.616 100.155 1.00 225.78 ? 68   GLU A O   1 
ATOM   185  C  CB  . GLU A 1 68  ? 137.646 150.730 97.192  1.00 225.78 ? 68   GLU A CB  1 
ATOM   186  N  N   . VAL A 1 69  ? 137.558 151.685 100.209 1.00 225.57 ? 69   VAL A N   1 
ATOM   187  C  CA  . VAL A 1 69  ? 137.991 151.546 101.596 1.00 225.57 ? 69   VAL A CA  1 
ATOM   188  C  C   . VAL A 1 69  ? 136.789 151.410 102.522 1.00 225.57 ? 69   VAL A C   1 
ATOM   189  O  O   . VAL A 1 69  ? 136.794 150.592 103.450 1.00 225.57 ? 69   VAL A O   1 
ATOM   190  C  CB  . VAL A 1 69  ? 138.885 152.734 101.998 1.00 225.57 ? 69   VAL A CB  1 
ATOM   191  N  N   . GLU A 1 70  ? 135.746 152.211 102.292 1.00 227.18 ? 70   GLU A N   1 
ATOM   192  C  CA  . GLU A 1 70  ? 134.545 152.119 103.116 1.00 227.18 ? 70   GLU A CA  1 
ATOM   193  C  C   . GLU A 1 70  ? 133.875 150.759 102.968 1.00 227.18 ? 70   GLU A C   1 
ATOM   194  O  O   . GLU A 1 70  ? 133.429 150.168 103.958 1.00 227.18 ? 70   GLU A O   1 
ATOM   195  C  CB  . GLU A 1 70  ? 133.571 153.240 102.751 1.00 227.18 ? 70   GLU A CB  1 
ATOM   196  N  N   . SER A 1 71  ? 133.794 150.245 101.737 1.00 226.78 ? 71   SER A N   1 
ATOM   197  C  CA  . SER A 1 71  ? 133.197 148.931 101.522 1.00 226.78 ? 71   SER A CA  1 
ATOM   198  C  C   . SER A 1 71  ? 134.015 147.835 102.195 1.00 226.78 ? 71   SER A C   1 
ATOM   199  O  O   . SER A 1 71  ? 133.450 146.913 102.796 1.00 226.78 ? 71   SER A O   1 
ATOM   200  C  CB  . SER A 1 71  ? 133.060 148.656 100.025 1.00 226.78 ? 71   SER A CB  1 
ATOM   201  N  N   . ALA A 1 72  ? 135.345 147.918 102.103 1.00 225.32 ? 72   ALA A N   1 
ATOM   202  C  CA  . ALA A 1 72  ? 136.194 146.931 102.761 1.00 225.32 ? 72   ALA A CA  1 
ATOM   203  C  C   . ALA A 1 72  ? 136.029 146.983 104.274 1.00 225.32 ? 72   ALA A C   1 
ATOM   204  O  O   . ALA A 1 72  ? 135.973 145.941 104.937 1.00 225.32 ? 72   ALA A O   1 
ATOM   205  C  CB  . ALA A 1 72  ? 137.655 147.150 102.370 1.00 225.32 ? 72   ALA A CB  1 
ATOM   206  N  N   . ARG A 1 73  ? 135.952 148.191 104.840 1.00 225.56 ? 73   ARG A N   1 
ATOM   207  C  CA  . ARG A 1 73  ? 135.750 148.323 106.279 1.00 225.56 ? 73   ARG A CA  1 
ATOM   208  C  C   . ARG A 1 73  ? 134.395 147.769 106.700 1.00 225.56 ? 73   ARG A C   1 
ATOM   209  O  O   . ARG A 1 73  ? 134.278 147.120 107.746 1.00 225.56 ? 73   ARG A O   1 
ATOM   210  C  CB  . ARG A 1 73  ? 135.886 149.787 106.696 1.00 225.56 ? 73   ARG A CB  1 
ATOM   211  N  N   . GLU A 1 74  ? 133.355 148.026 105.903 1.00 226.33 ? 74   GLU A N   1 
ATOM   212  C  CA  . GLU A 1 74  ? 132.029 147.511 106.228 1.00 226.33 ? 74   GLU A CA  1 
ATOM   213  C  C   . GLU A 1 74  ? 131.984 145.990 106.149 1.00 226.33 ? 74   GLU A C   1 
ATOM   214  O  O   . GLU A 1 74  ? 131.362 145.338 106.995 1.00 226.33 ? 74   GLU A O   1 
ATOM   215  C  CB  . GLU A 1 74  ? 130.986 148.127 105.295 1.00 226.33 ? 74   GLU A CB  1 
ATOM   216  N  N   . GLN A 1 75  ? 132.637 145.405 105.143 1.00 225.88 ? 75   GLN A N   1 
ATOM   217  C  CA  . GLN A 1 75  ? 132.547 143.962 104.941 1.00 225.88 ? 75   GLN A CA  1 
ATOM   218  C  C   . GLN A 1 75  ? 133.472 143.210 105.893 1.00 225.88 ? 75   GLN A C   1 
ATOM   219  O  O   . GLN A 1 75  ? 133.015 142.421 106.729 1.00 225.88 ? 75   GLN A O   1 
ATOM   220  C  CB  . GLN A 1 75  ? 132.872 143.618 103.486 1.00 225.88 ? 75   GLN A CB  1 
ATOM   221  N  N   . HIS A 1 76  ? 134.782 143.438 105.778 1.00 223.32 ? 76   HIS A N   1 
ATOM   222  C  CA  . HIS A 1 76  ? 135.740 142.697 106.591 1.00 223.32 ? 76   HIS A CA  1 
ATOM   223  C  C   . HIS A 1 76  ? 135.676 143.106 108.058 1.00 223.32 ? 76   HIS A C   1 
ATOM   224  O  O   . HIS A 1 76  ? 135.741 142.249 108.946 1.00 223.32 ? 76   HIS A O   1 
ATOM   225  C  CB  . HIS A 1 76  ? 137.154 142.896 106.046 1.00 223.32 ? 76   HIS A CB  1 
ATOM   226  N  N   . GLY A 1 77  ? 135.550 144.404 108.331 1.00 220.45 ? 77   GLY A N   1 
ATOM   227  C  CA  . GLY A 1 77  ? 135.504 144.921 109.678 1.00 220.45 ? 77   GLY A CA  1 
ATOM   228  C  C   . GLY A 1 77  ? 136.500 146.046 109.847 1.00 220.45 ? 77   GLY A C   1 
ATOM   229  O  O   . GLY A 1 77  ? 136.925 146.679 108.874 1.00 220.45 ? 77   GLY A O   1 
ATOM   230  N  N   . GLU A 1 78  ? 136.877 146.294 111.097 1.00 214.71 ? 78   GLU A N   1 
ATOM   231  C  CA  . GLU A 1 78  ? 137.828 147.339 111.444 1.00 214.71 ? 78   GLU A CA  1 
ATOM   232  C  C   . GLU A 1 78  ? 139.036 146.723 112.134 1.00 214.71 ? 78   GLU A C   1 
ATOM   233  O  O   . GLU A 1 78  ? 138.914 145.718 112.840 1.00 214.71 ? 78   GLU A O   1 
ATOM   234  C  CB  . GLU A 1 78  ? 137.186 148.394 112.351 1.00 214.71 ? 78   GLU A CB  1 
ATOM   235  N  N   . ASN A 1 79  ? 140.201 147.331 111.925 1.00 210.60 ? 79   ASN A N   1 
ATOM   236  C  CA  . ASN A 1 79  ? 141.423 146.848 112.545 1.00 210.60 ? 79   ASN A CA  1 
ATOM   237  C  C   . ASN A 1 79  ? 141.428 147.172 114.039 1.00 210.60 ? 79   ASN A C   1 
ATOM   238  O  O   . ASN A 1 79  ? 140.465 147.710 114.595 1.00 210.60 ? 79   ASN A O   1 
ATOM   239  C  CB  . ASN A 1 79  ? 142.647 147.458 111.863 1.00 210.60 ? 79   ASN A CB  1 
ATOM   240  N  N   . LYS A 1 80  ? 142.536 146.825 114.695 1.00 205.61 ? 80   LYS A N   1 
ATOM   241  C  CA  . LYS A 1 80  ? 142.689 147.062 116.125 1.00 205.61 ? 80   LYS A CA  1 
ATOM   242  C  C   . LYS A 1 80  ? 142.595 148.548 116.447 1.00 205.61 ? 80   LYS A C   1 
ATOM   243  O  O   . LYS A 1 80  ? 143.468 149.332 116.061 1.00 205.61 ? 80   LYS A O   1 
ATOM   244  C  CB  . LYS A 1 80  ? 144.021 146.494 116.621 1.00 205.61 ? 80   LYS A CB  1 
ATOM   245  N  N   . LEU A 1 81  ? 141.537 148.941 117.152 1.00 199.98 ? 81   LEU A N   1 
ATOM   246  C  CA  . LEU A 1 81  ? 141.348 150.339 117.496 1.00 199.98 ? 81   LEU A CA  1 
ATOM   247  C  C   . LEU A 1 81  ? 142.363 150.773 118.554 1.00 199.98 ? 81   LEU A C   1 
ATOM   248  O  O   . LEU A 1 81  ? 142.762 149.976 119.408 1.00 199.98 ? 81   LEU A O   1 
ATOM   249  C  CB  . LEU A 1 81  ? 139.930 150.575 118.009 1.00 199.98 ? 81   LEU A CB  1 
ATOM   250  N  N   . PRO A 1 82  ? 142.803 152.033 118.512 1.00 194.67 ? 82   PRO A N   1 
ATOM   251  C  CA  . PRO A 1 82  ? 143.730 152.515 119.548 1.00 194.67 ? 82   PRO A CA  1 
ATOM   252  C  C   . PRO A 1 82  ? 143.137 152.500 120.945 1.00 194.67 ? 82   PRO A C   1 
ATOM   253  O  O   . PRO A 1 82  ? 143.888 152.429 121.926 1.00 194.67 ? 82   PRO A O   1 
ATOM   254  C  CB  . PRO A 1 82  ? 144.057 153.944 119.088 1.00 194.67 ? 82   PRO A CB  1 
ATOM   255  C  CG  . PRO A 1 82  ? 142.912 154.333 118.209 1.00 194.67 ? 82   PRO A CG  1 
ATOM   256  C  CD  . PRO A 1 82  ? 142.490 153.073 117.518 1.00 194.67 ? 82   PRO A CD  1 
ATOM   257  N  N   . ALA A 1 83  ? 141.814 152.570 121.066 1.00 184.56 ? 83   ALA A N   1 
ATOM   258  C  CA  . ALA A 1 83  ? 141.177 152.572 122.375 1.00 184.56 ? 83   ALA A CA  1 
ATOM   259  C  C   . ALA A 1 83  ? 141.364 151.229 123.070 1.00 184.56 ? 83   ALA A C   1 
ATOM   260  O  O   . ALA A 1 83  ? 141.319 150.170 122.438 1.00 184.56 ? 83   ALA A O   1 
ATOM   261  C  CB  . ALA A 1 83  ? 139.689 152.892 122.242 1.00 184.56 ? 83   ALA A CB  1 
ATOM   262  N  N   . GLN A 1 84  ? 141.575 151.280 124.383 1.00 167.46 ? 84   GLN A N   1 
ATOM   263  C  CA  . GLN A 1 84  ? 141.760 150.093 125.202 1.00 167.46 ? 84   GLN A CA  1 
ATOM   264  C  C   . GLN A 1 84  ? 140.804 150.146 126.386 1.00 167.46 ? 84   GLN A C   1 
ATOM   265  O  O   . GLN A 1 84  ? 140.135 151.154 126.630 1.00 167.46 ? 84   GLN A O   1 
ATOM   266  C  CB  . GLN A 1 84  ? 143.210 149.965 125.688 1.00 167.46 ? 84   GLN A CB  1 
ATOM   267  N  N   . GLN A 1 85  ? 140.744 149.045 127.121 1.00 157.59 ? 85   GLN A N   1 
ATOM   268  C  CA  . GLN A 1 85  ? 139.856 148.958 128.275 1.00 157.59 ? 85   GLN A CA  1 
ATOM   269  C  C   . GLN A 1 85  ? 140.353 149.871 129.387 1.00 157.59 ? 85   GLN A C   1 
ATOM   270  O  O   . GLN A 1 85  ? 141.507 149.737 129.817 1.00 157.59 ? 85   GLN A O   1 
ATOM   271  C  CB  . GLN A 1 85  ? 139.769 147.517 128.768 1.00 157.59 ? 85   GLN A CB  1 
ATOM   272  N  N   . PRO A 1 86  ? 139.539 150.799 129.880 1.00 142.79 ? 86   PRO A N   1 
ATOM   273  C  CA  . PRO A 1 86  ? 139.992 151.689 130.949 1.00 142.79 ? 86   PRO A CA  1 
ATOM   274  C  C   . PRO A 1 86  ? 139.828 151.059 132.323 1.00 142.79 ? 86   PRO A C   1 
ATOM   275  O  O   . PRO A 1 86  ? 138.978 150.194 132.545 1.00 142.79 ? 86   PRO A O   1 
ATOM   276  C  CB  . PRO A 1 86  ? 139.085 152.915 130.793 1.00 142.79 ? 86   PRO A CB  1 
ATOM   277  C  CG  . PRO A 1 86  ? 137.830 152.383 130.160 1.00 142.79 ? 86   PRO A CG  1 
ATOM   278  C  CD  . PRO A 1 86  ? 138.148 151.072 129.478 1.00 142.79 ? 86   PRO A CD  1 
ATOM   279  N  N   . SER A 1 87  ? 140.665 151.508 133.248 1.00 123.87 ? 87   SER A N   1 
ATOM   280  C  CA  . SER A 1 87  ? 140.622 150.983 134.606 1.00 123.87 ? 87   SER A CA  1 
ATOM   281  C  C   . SER A 1 87  ? 139.420 151.557 135.349 1.00 123.87 ? 87   SER A C   1 
ATOM   282  O  O   . SER A 1 87  ? 139.280 152.783 135.438 1.00 123.87 ? 87   SER A O   1 
ATOM   283  C  CB  . SER A 1 87  ? 141.912 151.320 135.350 1.00 123.87 ? 87   SER A CB  1 
ATOM   284  N  N   . PRO A 1 88  ? 138.538 150.719 135.886 1.00 109.62 ? 88   PRO A N   1 
ATOM   285  C  CA  . PRO A 1 88  ? 137.407 151.235 136.664 1.00 109.62 ? 88   PRO A CA  1 
ATOM   286  C  C   . PRO A 1 88  ? 137.874 151.903 137.948 1.00 109.62 ? 88   PRO A C   1 
ATOM   287  O  O   . PRO A 1 88  ? 138.947 151.614 138.483 1.00 109.62 ? 88   PRO A O   1 
ATOM   288  C  CB  . PRO A 1 88  ? 136.577 149.980 136.962 1.00 109.62 ? 88   PRO A CB  1 
ATOM   289  C  CG  . PRO A 1 88  ? 136.991 148.993 135.914 1.00 109.62 ? 88   PRO A CG  1 
ATOM   290  C  CD  . PRO A 1 88  ? 138.447 149.264 135.686 1.00 109.62 ? 88   PRO A CD  1 
ATOM   291  N  N   . TRP A 1 89  ? 137.040 152.824 138.437 1.00 100.82 ? 89   TRP A N   1 
ATOM   292  C  CA  . TRP A 1 89  ? 137.355 153.516 139.683 1.00 100.82 ? 89   TRP A CA  1 
ATOM   293  C  C   . TRP A 1 89  ? 137.432 152.541 140.850 1.00 100.82 ? 89   TRP A C   1 
ATOM   294  O  O   . TRP A 1 89  ? 138.333 152.637 141.691 1.00 100.82 ? 89   TRP A O   1 
ATOM   295  C  CB  . TRP A 1 89  ? 136.314 154.601 139.958 1.00 100.82 ? 89   TRP A CB  1 
ATOM   296  N  N   . TRP A 1 90  ? 136.496 151.594 140.919 1.00 96.02  ? 90   TRP A N   1 
ATOM   297  C  CA  . TRP A 1 90  ? 136.526 150.593 141.977 1.00 96.02  ? 90   TRP A CA  1 
ATOM   298  C  C   . TRP A 1 90  ? 137.721 149.657 141.848 1.00 96.02  ? 90   TRP A C   1 
ATOM   299  O  O   . TRP A 1 90  ? 138.327 149.292 142.860 1.00 96.02  ? 90   TRP A O   1 
ATOM   300  C  CB  . TRP A 1 90  ? 135.226 149.787 141.974 1.00 96.02  ? 90   TRP A CB  1 
ATOM   301  N  N   . VAL A 1 91  ? 138.071 149.258 140.624 1.00 95.58  ? 91   VAL A N   1 
ATOM   302  C  CA  . VAL A 1 91  ? 139.186 148.336 140.434 1.00 95.58  ? 91   VAL A CA  1 
ATOM   303  C  C   . VAL A 1 91  ? 140.507 149.009 140.780 1.00 95.58  ? 91   VAL A C   1 
ATOM   304  O  O   . VAL A 1 91  ? 141.412 148.378 141.338 1.00 95.58  ? 91   VAL A O   1 
ATOM   305  C  CB  . VAL A 1 91  ? 139.189 147.789 138.996 1.00 95.58  ? 91   VAL A CB  1 
ATOM   306  N  N   . HIS A 1 92  ? 140.645 150.295 140.448 1.00 90.96  ? 92   HIS A N   1 
ATOM   307  C  CA  . HIS A 1 92  ? 141.894 150.999 140.720 1.00 90.96  ? 92   HIS A CA  1 
ATOM   308  C  C   . HIS A 1 92  ? 142.148 151.142 142.214 1.00 90.96  ? 92   HIS A C   1 
ATOM   309  O  O   . HIS A 1 92  ? 143.306 151.161 142.649 1.00 90.96  ? 92   HIS A O   1 
ATOM   310  C  CB  . HIS A 1 92  ? 141.877 152.372 140.051 1.00 90.96  ? 92   HIS A CB  1 
ATOM   311  C  CG  . HIS A 1 92  ? 143.093 153.197 140.334 1.00 90.96  ? 92   HIS A CG  1 
ATOM   312  N  ND1 . HIS A 1 92  ? 143.167 154.075 141.394 1.00 90.96  ? 92   HIS A ND1 1 
ATOM   313  C  CD2 . HIS A 1 92  ? 144.285 153.277 139.696 1.00 90.96  ? 92   HIS A CD2 1 
ATOM   314  C  CE1 . HIS A 1 92  ? 144.350 154.662 141.395 1.00 90.96  ? 92   HIS A CE1 1 
ATOM   315  N  NE2 . HIS A 1 92  ? 145.048 154.195 140.375 1.00 90.96  ? 92   HIS A NE2 1 
ATOM   316  N  N   . LEU A 1 93  ? 141.086 151.242 143.014 1.00 84.01  ? 93   LEU A N   1 
ATOM   317  C  CA  . LEU A 1 93  ? 141.267 151.367 144.455 1.00 84.01  ? 93   LEU A CA  1 
ATOM   318  C  C   . LEU A 1 93  ? 141.898 150.119 145.055 1.00 84.01  ? 93   LEU A C   1 
ATOM   319  O  O   . LEU A 1 93  ? 142.658 150.221 146.024 1.00 84.01  ? 93   LEU A O   1 
ATOM   320  C  CB  . LEU A 1 93  ? 139.931 151.669 145.131 1.00 84.01  ? 93   LEU A CB  1 
ATOM   321  C  CG  . LEU A 1 93  ? 139.621 153.140 145.423 1.00 84.01  ? 93   LEU A CG  1 
ATOM   322  C  CD1 . LEU A 1 93  ? 140.318 153.584 146.694 1.00 84.01  ? 93   LEU A CD1 1 
ATOM   323  C  CD2 . LEU A 1 93  ? 140.025 154.033 144.260 1.00 84.01  ? 93   LEU A CD2 1 
ATOM   324  N  N   . TRP A 1 94  ? 141.602 148.940 144.505 1.00 79.51  ? 94   TRP A N   1 
ATOM   325  C  CA  . TRP A 1 94  ? 142.183 147.719 145.051 1.00 79.51  ? 94   TRP A CA  1 
ATOM   326  C  C   . TRP A 1 94  ? 143.690 147.678 144.836 1.00 79.51  ? 94   TRP A C   1 
ATOM   327  O  O   . TRP A 1 94  ? 144.454 147.459 145.782 1.00 79.51  ? 94   TRP A O   1 
ATOM   328  C  CB  . TRP A 1 94  ? 141.522 146.487 144.438 1.00 79.51  ? 94   TRP A CB  1 
ATOM   329  C  CG  . TRP A 1 94  ? 142.074 145.214 144.996 1.00 79.51  ? 94   TRP A CG  1 
ATOM   330  C  CD1 . TRP A 1 94  ? 142.777 144.261 144.321 1.00 79.51  ? 94   TRP A CD1 1 
ATOM   331  C  CD2 . TRP A 1 94  ? 142.002 144.771 146.357 1.00 79.51  ? 94   TRP A CD2 1 
ATOM   332  N  NE1 . TRP A 1 94  ? 143.130 143.243 145.172 1.00 79.51  ? 94   TRP A NE1 1 
ATOM   333  C  CE2 . TRP A 1 94  ? 142.669 143.534 146.429 1.00 79.51  ? 94   TRP A CE2 1 
ATOM   334  C  CE3 . TRP A 1 94  ? 141.430 145.297 147.519 1.00 79.51  ? 94   TRP A CE3 1 
ATOM   335  C  CZ2 . TRP A 1 94  ? 142.780 142.814 147.615 1.00 79.51  ? 94   TRP A CZ2 1 
ATOM   336  C  CZ3 . TRP A 1 94  ? 141.542 144.581 148.695 1.00 79.51  ? 94   TRP A CZ3 1 
ATOM   337  C  CH2 . TRP A 1 94  ? 142.211 143.353 148.735 1.00 79.51  ? 94   TRP A CH2 1 
ATOM   338  N  N   . VAL A 1 95  ? 144.141 147.899 143.598 1.00 77.50  ? 95   VAL A N   1 
ATOM   339  C  CA  . VAL A 1 95  ? 145.579 147.931 143.347 1.00 77.50  ? 95   VAL A CA  1 
ATOM   340  C  C   . VAL A 1 95  ? 146.213 149.100 144.090 1.00 77.50  ? 95   VAL A C   1 
ATOM   341  O  O   . VAL A 1 95  ? 147.403 149.065 144.427 1.00 77.50  ? 95   VAL A O   1 
ATOM   342  C  CB  . VAL A 1 95  ? 145.865 147.980 141.832 1.00 77.50  ? 95   VAL A CB  1 
ATOM   343  C  CG1 . VAL A 1 95  ? 145.196 149.180 141.190 1.00 77.50  ? 95   VAL A CG1 1 
ATOM   344  C  CG2 . VAL A 1 95  ? 147.364 147.982 141.557 1.00 77.50  ? 95   VAL A CG2 1 
ATOM   345  N  N   . CYS A 1 96  ? 145.426 150.136 144.385 1.00 75.14  ? 96   CYS A N   1 
ATOM   346  C  CA  . CYS A 1 96  ? 145.899 151.230 145.221 1.00 75.14  ? 96   CYS A CA  1 
ATOM   347  C  C   . CYS A 1 96  ? 145.960 150.851 146.696 1.00 75.14  ? 96   CYS A C   1 
ATOM   348  O  O   . CYS A 1 96  ? 146.277 151.706 147.528 1.00 75.14  ? 96   CYS A O   1 
ATOM   349  C  CB  . CYS A 1 96  ? 144.993 152.444 145.033 1.00 75.14  ? 96   CYS A CB  1 
ATOM   350  S  SG  . CYS A 1 96  ? 145.846 154.017 145.105 1.00 75.14  ? 96   CYS A SG  1 
ATOM   351  N  N   . TYR A 1 97  ? 145.652 149.599 147.041 1.00 69.22  ? 97   TYR A N   1 
ATOM   352  C  CA  . TYR A 1 97  ? 145.534 149.172 148.431 1.00 69.22  ? 97   TYR A CA  1 
ATOM   353  C  C   . TYR A 1 97  ? 146.399 147.947 148.727 1.00 69.22  ? 97   TYR A C   1 
ATOM   354  O  O   . TYR A 1 97  ? 146.710 147.678 149.890 1.00 69.22  ? 97   TYR A O   1 
ATOM   355  C  CB  . TYR A 1 97  ? 144.050 148.934 148.745 1.00 69.22  ? 97   TYR A CB  1 
ATOM   356  C  CG  . TYR A 1 97  ? 143.657 148.475 150.141 1.00 69.22  ? 97   TYR A CG  1 
ATOM   357  C  CD1 . TYR A 1 97  ? 142.813 149.254 150.919 1.00 69.22  ? 97   TYR A CD1 1 
ATOM   358  C  CD2 . TYR A 1 97  ? 144.017 147.228 150.630 1.00 69.22  ? 97   TYR A CD2 1 
ATOM   359  C  CE1 . TYR A 1 97  ? 142.420 148.848 152.173 1.00 69.22  ? 97   TYR A CE1 1 
ATOM   360  C  CE2 . TYR A 1 97  ? 143.630 146.814 151.884 1.00 69.22  ? 97   TYR A CE2 1 
ATOM   361  C  CZ  . TYR A 1 97  ? 142.827 147.626 152.649 1.00 69.22  ? 97   TYR A CZ  1 
ATOM   362  O  OH  . TYR A 1 97  ? 142.430 147.212 153.899 1.00 69.22  ? 97   TYR A OH  1 
ATOM   363  N  N   . ARG A 1 98  ? 146.859 147.239 147.696 1.00 70.92  ? 98   ARG A N   1 
ATOM   364  C  CA  . ARG A 1 98  ? 147.592 145.992 147.877 1.00 70.92  ? 98   ARG A CA  1 
ATOM   365  C  C   . ARG A 1 98  ? 148.953 146.162 148.543 1.00 70.92  ? 98   ARG A C   1 
ATOM   366  O  O   . ARG A 1 98  ? 149.553 145.156 148.935 1.00 70.92  ? 98   ARG A O   1 
ATOM   367  C  CB  . ARG A 1 98  ? 147.795 145.290 146.528 1.00 70.92  ? 98   ARG A CB  1 
ATOM   368  C  CG  . ARG A 1 98  ? 146.558 145.222 145.657 1.00 70.92  ? 98   ARG A CG  1 
ATOM   369  C  CD  . ARG A 1 98  ? 146.299 143.808 145.167 1.00 70.92  ? 98   ARG A CD  1 
ATOM   370  N  NE  . ARG A 1 98  ? 147.299 143.375 144.200 1.00 70.92  ? 98   ARG A NE  1 
ATOM   371  C  CZ  . ARG A 1 98  ? 147.301 143.718 142.919 1.00 70.92  ? 98   ARG A CZ  1 
ATOM   372  N  NH1 . ARG A 1 98  ? 146.366 144.505 142.414 1.00 70.92  ? 98   ARG A NH1 1 
ATOM   373  N  NH2 . ARG A 1 98  ? 148.264 143.261 142.125 1.00 70.92  ? 98   ARG A NH2 1 
ATOM   374  N  N   . ASN A 1 99  ? 149.458 147.386 148.674 1.00 59.92  ? 99   ASN A N   1 
ATOM   375  C  CA  . ASN A 1 99  ? 150.800 147.577 149.202 1.00 59.92  ? 99   ASN A CA  1 
ATOM   376  C  C   . ASN A 1 99  ? 150.877 147.101 150.654 1.00 59.92  ? 99   ASN A C   1 
ATOM   377  O  O   . ASN A 1 99  ? 149.910 147.226 151.409 1.00 59.92  ? 99   ASN A O   1 
ATOM   378  C  CB  . ASN A 1 99  ? 151.213 149.042 149.097 1.00 59.92  ? 99   ASN A CB  1 
ATOM   379  C  CG  . ASN A 1 99  ? 150.105 149.986 149.488 1.00 59.92  ? 99   ASN A CG  1 
ATOM   380  O  OD1 . ASN A 1 99  ? 149.038 149.560 149.925 1.00 59.92  ? 99   ASN A OD1 1 
ATOM   381  N  ND2 . ASN A 1 99  ? 150.350 151.281 149.332 1.00 59.92  ? 99   ASN A ND2 1 
ATOM   382  N  N   . PRO A 1 100 ? 152.019 146.538 151.063 1.00 53.89  ? 100  PRO A N   1 
ATOM   383  C  CA  . PRO A 1 100 ? 152.086 145.876 152.378 1.00 53.89  ? 100  PRO A CA  1 
ATOM   384  C  C   . PRO A 1 100 ? 151.812 146.791 153.557 1.00 53.89  ? 100  PRO A C   1 
ATOM   385  O  O   . PRO A 1 100 ? 151.284 146.324 154.574 1.00 53.89  ? 100  PRO A O   1 
ATOM   386  C  CB  . PRO A 1 100 ? 153.518 145.326 152.420 1.00 53.89  ? 100  PRO A CB  1 
ATOM   387  C  CG  . PRO A 1 100 ? 154.273 146.145 151.436 1.00 53.89  ? 100  PRO A CG  1 
ATOM   388  C  CD  . PRO A 1 100 ? 153.303 146.474 150.349 1.00 53.89  ? 100  PRO A CD  1 
ATOM   389  N  N   . PHE A 1 101 ? 152.171 148.071 153.468 1.00 48.37  ? 101  PHE A N   1 
ATOM   390  C  CA  . PHE A 1 101 ? 151.975 148.965 154.604 1.00 48.37  ? 101  PHE A CA  1 
ATOM   391  C  C   . PHE A 1 101 ? 150.499 149.076 154.961 1.00 48.37  ? 101  PHE A C   1 
ATOM   392  O  O   . PHE A 1 101 ? 150.125 149.002 156.137 1.00 48.37  ? 101  PHE A O   1 
ATOM   393  C  CB  . PHE A 1 101 ? 152.560 150.341 154.298 1.00 48.37  ? 101  PHE A CB  1 
ATOM   394  C  CG  . PHE A 1 101 ? 152.288 151.359 155.362 1.00 48.37  ? 101  PHE A CG  1 
ATOM   395  C  CD1 . PHE A 1 101 ? 153.039 151.382 156.520 1.00 48.37  ? 101  PHE A CD1 1 
ATOM   396  C  CD2 . PHE A 1 101 ? 151.279 152.291 155.206 1.00 48.37  ? 101  PHE A CD2 1 
ATOM   397  C  CE1 . PHE A 1 101 ? 152.791 152.315 157.501 1.00 48.37  ? 101  PHE A CE1 1 
ATOM   398  C  CE2 . PHE A 1 101 ? 151.026 153.225 156.184 1.00 48.37  ? 101  PHE A CE2 1 
ATOM   399  C  CZ  . PHE A 1 101 ? 151.783 153.238 157.332 1.00 48.37  ? 101  PHE A CZ  1 
ATOM   400  N  N   . ASN A 1 102 ? 149.642 149.246 153.954 1.00 54.77  ? 102  ASN A N   1 
ATOM   401  C  CA  . ASN A 1 102 ? 148.214 149.353 154.219 1.00 54.77  ? 102  ASN A CA  1 
ATOM   402  C  C   . ASN A 1 102 ? 147.641 148.044 154.739 1.00 54.77  ? 102  ASN A C   1 
ATOM   403  O  O   . ASN A 1 102 ? 146.736 148.060 155.578 1.00 54.77  ? 102  ASN A O   1 
ATOM   404  C  CB  . ASN A 1 102 ? 147.474 149.796 152.962 1.00 54.77  ? 102  ASN A CB  1 
ATOM   405  C  CG  . ASN A 1 102 ? 147.793 151.221 152.578 1.00 54.77  ? 102  ASN A CG  1 
ATOM   406  O  OD1 . ASN A 1 102 ? 147.665 152.135 153.387 1.00 54.77  ? 102  ASN A OD1 1 
ATOM   407  N  ND2 . ASN A 1 102 ? 148.202 151.420 151.336 1.00 54.77  ? 102  ASN A ND2 1 
ATOM   408  N  N   . ILE A 1 103 ? 148.152 146.908 154.264 1.00 54.78  ? 103  ILE A N   1 
ATOM   409  C  CA  . ILE A 1 103 ? 147.696 145.617 154.775 1.00 54.78  ? 103  ILE A CA  1 
ATOM   410  C  C   . ILE A 1 103 ? 148.035 145.484 156.254 1.00 54.78  ? 103  ILE A C   1 
ATOM   411  O  O   . ILE A 1 103 ? 147.199 145.075 157.070 1.00 54.78  ? 103  ILE A O   1 
ATOM   412  C  CB  . ILE A 1 103 ? 148.309 144.471 153.953 1.00 54.78  ? 103  ILE A CB  1 
ATOM   413  C  CG1 . ILE A 1 103 ? 147.811 144.534 152.510 1.00 54.78  ? 103  ILE A CG1 1 
ATOM   414  C  CG2 . ILE A 1 103 ? 147.983 143.131 154.584 1.00 54.78  ? 103  ILE A CG2 1 
ATOM   415  C  CD1 . ILE A 1 103 ? 146.309 144.454 152.387 1.00 54.78  ? 103  ILE A CD1 1 
ATOM   416  N  N   . LEU A 1 104 ? 149.271 145.830 156.621 1.00 51.93  ? 104  LEU A N   1 
ATOM   417  C  CA  . LEU A 1 104 ? 149.675 145.772 158.022 1.00 51.93  ? 104  LEU A CA  1 
ATOM   418  C  C   . LEU A 1 104 ? 148.838 146.715 158.875 1.00 51.93  ? 104  LEU A C   1 
ATOM   419  O  O   . LEU A 1 104 ? 148.407 146.355 159.978 1.00 51.93  ? 104  LEU A O   1 
ATOM   420  C  CB  . LEU A 1 104 ? 151.159 146.111 158.149 1.00 51.93  ? 104  LEU A CB  1 
ATOM   421  C  CG  . LEU A 1 104 ? 151.634 146.593 159.518 1.00 51.93  ? 104  LEU A CG  1 
ATOM   422  C  CD1 . LEU A 1 104 ? 151.557 145.466 160.529 1.00 51.93  ? 104  LEU A CD1 1 
ATOM   423  C  CD2 . LEU A 1 104 ? 153.045 147.149 159.430 1.00 51.93  ? 104  LEU A CD2 1 
ATOM   424  N  N   . LEU A 1 105 ? 148.600 147.929 158.379 1.00 52.91  ? 105  LEU A N   1 
ATOM   425  C  CA  . LEU A 1 105 ? 147.809 148.889 159.135 1.00 52.91  ? 105  LEU A CA  1 
ATOM   426  C  C   . LEU A 1 105 ? 146.380 148.398 159.317 1.00 52.91  ? 105  LEU A C   1 
ATOM   427  O  O   . LEU A 1 105 ? 145.797 148.547 160.395 1.00 52.91  ? 105  LEU A O   1 
ATOM   428  C  CB  . LEU A 1 105 ? 147.829 150.244 158.434 1.00 52.91  ? 105  LEU A CB  1 
ATOM   429  C  CG  . LEU A 1 105 ? 147.796 151.453 159.360 1.00 52.91  ? 105  LEU A CG  1 
ATOM   430  C  CD1 . LEU A 1 105 ? 149.024 151.441 160.242 1.00 52.91  ? 105  LEU A CD1 1 
ATOM   431  C  CD2 . LEU A 1 105 ? 147.722 152.734 158.555 1.00 52.91  ? 105  LEU A CD2 1 
ATOM   432  N  N   . THR A 1 106 ? 145.798 147.808 158.271 1.00 54.61  ? 106  THR A N   1 
ATOM   433  C  CA  . THR A 1 106 ? 144.448 147.269 158.378 1.00 54.61  ? 106  THR A CA  1 
ATOM   434  C  C   . THR A 1 106 ? 144.393 146.128 159.382 1.00 54.61  ? 106  THR A C   1 
ATOM   435  O  O   . THR A 1 106 ? 143.438 146.021 160.161 1.00 54.61  ? 106  THR A O   1 
ATOM   436  C  CB  . THR A 1 106 ? 143.961 146.800 157.008 1.00 54.61  ? 106  THR A CB  1 
ATOM   437  O  OG1 . THR A 1 106 ? 144.096 147.866 156.060 1.00 54.61  ? 106  THR A OG1 1 
ATOM   438  C  CG2 . THR A 1 106 ? 142.502 146.381 157.077 1.00 54.61  ? 106  THR A CG2 1 
ATOM   439  N  N   . ILE A 1 107 ? 145.406 145.260 159.374 1.00 54.19  ? 107  ILE A N   1 
ATOM   440  C  CA  . ILE A 1 107 ? 145.444 144.157 160.331 1.00 54.19  ? 107  ILE A CA  1 
ATOM   441  C  C   . ILE A 1 107 ? 145.506 144.695 161.754 1.00 54.19  ? 107  ILE A C   1 
ATOM   442  O  O   . ILE A 1 107 ? 144.785 144.230 162.645 1.00 54.19  ? 107  ILE A O   1 
ATOM   443  C  CB  . ILE A 1 107 ? 146.628 143.222 160.027 1.00 54.19  ? 107  ILE A CB  1 
ATOM   444  C  CG1 . ILE A 1 107 ? 146.323 142.364 158.798 1.00 54.19  ? 107  ILE A CG1 1 
ATOM   445  C  CG2 . ILE A 1 107 ? 146.939 142.344 161.226 1.00 54.19  ? 107  ILE A CG2 1 
ATOM   446  C  CD1 . ILE A 1 107 ? 147.502 141.555 158.312 1.00 54.19  ? 107  ILE A CD1 1 
ATOM   447  N  N   . LEU A 1 108 ? 146.363 145.693 161.984 1.00 53.66  ? 108  LEU A N   1 
ATOM   448  C  CA  . LEU A 1 108 ? 146.468 146.276 163.319 1.00 53.66  ? 108  LEU A CA  1 
ATOM   449  C  C   . LEU A 1 108 ? 145.162 146.936 163.741 1.00 53.66  ? 108  LEU A C   1 
ATOM   450  O  O   . LEU A 1 108 ? 144.736 146.803 164.893 1.00 53.66  ? 108  LEU A O   1 
ATOM   451  C  CB  . LEU A 1 108 ? 147.614 147.284 163.373 1.00 53.66  ? 108  LEU A CB  1 
ATOM   452  C  CG  . LEU A 1 108 ? 149.022 146.703 163.475 1.00 53.66  ? 108  LEU A CG  1 
ATOM   453  C  CD1 . LEU A 1 108 ? 150.006 147.793 163.834 1.00 53.66  ? 108  LEU A CD1 1 
ATOM   454  C  CD2 . LEU A 1 108 ? 149.068 145.583 164.494 1.00 53.66  ? 108  LEU A CD2 1 
ATOM   455  N  N   . GLY A 1 109 ? 144.511 147.651 162.823 1.00 58.71  ? 109  GLY A N   1 
ATOM   456  C  CA  . GLY A 1 109 ? 143.252 148.293 163.160 1.00 58.71  ? 109  GLY A CA  1 
ATOM   457  C  C   . GLY A 1 109 ? 142.160 147.295 163.495 1.00 58.71  ? 109  GLY A C   1 
ATOM   458  O  O   . GLY A 1 109 ? 141.423 147.471 164.468 1.00 58.71  ? 109  GLY A O   1 
ATOM   459  N  N   . ALA A 1 110 ? 142.048 146.229 162.699 1.00 62.65  ? 110  ALA A N   1 
ATOM   460  C  CA  . ALA A 1 110 ? 141.057 145.196 162.983 1.00 62.65  ? 110  ALA A CA  1 
ATOM   461  C  C   . ALA A 1 110 ? 141.338 144.516 164.316 1.00 62.65  ? 110  ALA A C   1 
ATOM   462  O  O   . ALA A 1 110 ? 140.414 144.261 165.100 1.00 62.65  ? 110  ALA A O   1 
ATOM   463  C  CB  . ALA A 1 110 ? 141.028 144.170 161.851 1.00 62.65  ? 110  ALA A CB  1 
ATOM   464  N  N   . ILE A 1 111 ? 142.609 144.219 164.595 1.00 60.66  ? 111  ILE A N   1 
ATOM   465  C  CA  . ILE A 1 111 ? 142.956 143.590 165.863 1.00 60.66  ? 111  ILE A CA  1 
ATOM   466  C  C   . ILE A 1 111 ? 142.605 144.507 167.028 1.00 60.66  ? 111  ILE A C   1 
ATOM   467  O  O   . ILE A 1 111 ? 142.027 144.067 168.028 1.00 60.66  ? 111  ILE A O   1 
ATOM   468  C  CB  . ILE A 1 111 ? 144.444 143.200 165.870 1.00 60.66  ? 111  ILE A CB  1 
ATOM   469  C  CG1 . ILE A 1 111 ? 144.650 141.906 165.084 1.00 60.66  ? 111  ILE A CG1 1 
ATOM   470  C  CG2 . ILE A 1 111 ? 144.946 143.035 167.289 1.00 60.66  ? 111  ILE A CG2 1 
ATOM   471  C  CD1 . ILE A 1 111 ? 144.207 140.667 165.825 1.00 60.66  ? 111  ILE A CD1 1 
ATOM   472  N  N   . SER A 1 112 ? 142.929 145.797 166.912 1.00 64.46  ? 112  SER A N   1 
ATOM   473  C  CA  . SER A 1 112 ? 142.590 146.741 167.971 1.00 64.46  ? 112  SER A CA  1 
ATOM   474  C  C   . SER A 1 112 ? 141.082 146.838 168.158 1.00 64.46  ? 112  SER A C   1 
ATOM   475  O  O   . SER A 1 112 ? 140.598 146.983 169.286 1.00 64.46  ? 112  SER A O   1 
ATOM   476  C  CB  . SER A 1 112 ? 143.184 148.115 167.662 1.00 64.46  ? 112  SER A CB  1 
ATOM   477  O  OG  . SER A 1 112 ? 144.592 148.107 167.819 1.00 64.46  ? 112  SER A OG  1 
ATOM   478  N  N   . TYR A 1 113 ? 140.323 146.764 167.064 1.00 67.02  ? 113  TYR A N   1 
ATOM   479  C  CA  . TYR A 1 113 ? 138.869 146.728 167.177 1.00 67.02  ? 113  TYR A CA  1 
ATOM   480  C  C   . TYR A 1 113 ? 138.431 145.498 167.961 1.00 67.02  ? 113  TYR A C   1 
ATOM   481  O  O   . TYR A 1 113 ? 137.543 145.579 168.818 1.00 67.02  ? 113  TYR A O   1 
ATOM   482  C  CB  . TYR A 1 113 ? 138.244 146.740 165.777 1.00 67.02  ? 113  TYR A CB  1 
ATOM   483  C  CG  . TYR A 1 113 ? 136.735 146.566 165.704 1.00 67.02  ? 113  TYR A CG  1 
ATOM   484  C  CD1 . TYR A 1 113 ? 136.130 146.139 164.528 1.00 67.02  ? 113  TYR A CD1 1 
ATOM   485  C  CD2 . TYR A 1 113 ? 135.911 146.905 166.771 1.00 67.02  ? 113  TYR A CD2 1 
ATOM   486  C  CE1 . TYR A 1 113 ? 134.759 145.994 164.439 1.00 67.02  ? 113  TYR A CE1 1 
ATOM   487  C  CE2 . TYR A 1 113 ? 134.539 146.761 166.692 1.00 67.02  ? 113  TYR A CE2 1 
ATOM   488  C  CZ  . TYR A 1 113 ? 133.968 146.310 165.523 1.00 67.02  ? 113  TYR A CZ  1 
ATOM   489  O  OH  . TYR A 1 113 ? 132.602 146.174 165.438 1.00 67.02  ? 113  TYR A OH  1 
ATOM   490  N  N   . ALA A 1 114 ? 139.066 144.354 167.699 1.00 67.84  ? 114  ALA A N   1 
ATOM   491  C  CA  . ALA A 1 114 ? 138.692 143.126 168.393 1.00 67.84  ? 114  ALA A CA  1 
ATOM   492  C  C   . ALA A 1 114 ? 138.914 143.240 169.896 1.00 67.84  ? 114  ALA A C   1 
ATOM   493  O  O   . ALA A 1 114 ? 138.085 142.777 170.687 1.00 67.84  ? 114  ALA A O   1 
ATOM   494  C  CB  . ALA A 1 114 ? 139.473 141.942 167.825 1.00 67.84  ? 114  ALA A CB  1 
ATOM   495  N  N   . THR A 1 115 ? 140.018 143.855 170.313 1.00 69.94  ? 115  THR A N   1 
ATOM   496  C  CA  . THR A 1 115 ? 140.339 143.966 171.736 1.00 69.94  ? 115  THR A CA  1 
ATOM   497  C  C   . THR A 1 115 ? 139.773 145.242 172.352 1.00 69.94  ? 115  THR A C   1 
ATOM   498  O  O   . THR A 1 115 ? 140.475 145.989 173.032 1.00 69.94  ? 115  THR A O   1 
ATOM   499  C  CB  . THR A 1 115 ? 141.848 143.892 171.938 1.00 69.94  ? 115  THR A CB  1 
ATOM   500  O  OG1 . THR A 1 115 ? 142.426 145.184 171.716 1.00 69.94  ? 115  THR A OG1 1 
ATOM   501  C  CG2 . THR A 1 115 ? 142.466 142.889 170.980 1.00 69.94  ? 115  THR A CG2 1 
ATOM   502  N  N   . GLU A 1 116 ? 138.479 145.477 172.121 1.00 72.36  ? 116  GLU A N   1 
ATOM   503  C  CA  . GLU A 1 116 ? 137.702 146.517 172.802 1.00 72.36  ? 116  GLU A CA  1 
ATOM   504  C  C   . GLU A 1 116 ? 138.418 147.868 172.807 1.00 72.36  ? 116  GLU A C   1 
ATOM   505  O  O   . GLU A 1 116 ? 138.520 148.543 173.834 1.00 72.36  ? 116  GLU A O   1 
ATOM   506  C  CB  . GLU A 1 116 ? 137.347 146.083 174.227 1.00 72.36  ? 116  GLU A CB  1 
ATOM   507  C  CG  . GLU A 1 116 ? 137.282 144.573 174.434 1.00 72.36  ? 116  GLU A CG  1 
ATOM   508  C  CD  . GLU A 1 116 ? 136.803 144.192 175.822 1.00 72.36  ? 116  GLU A CD  1 
ATOM   509  O  OE1 . GLU A 1 116 ? 137.487 143.386 176.488 1.00 72.36  ? 116  GLU A OE1 1 
ATOM   510  O  OE2 . GLU A 1 116 ? 135.743 144.698 176.247 1.00 72.36  ? 116  GLU A OE2 1 
ATOM   511  N  N   . ASP A 1 117 ? 138.923 148.267 171.640 1.00 64.44  ? 117  ASP A N   1 
ATOM   512  C  CA  . ASP A 1 117 ? 139.603 149.559 171.486 1.00 64.44  ? 117  ASP A CA  1 
ATOM   513  C  C   . ASP A 1 117 ? 139.079 150.214 170.210 1.00 64.44  ? 117  ASP A C   1 
ATOM   514  O  O   . ASP A 1 117 ? 139.635 150.023 169.126 1.00 64.44  ? 117  ASP A O   1 
ATOM   515  C  CB  . ASP A 1 117 ? 141.115 149.390 171.456 1.00 64.44  ? 117  ASP A CB  1 
ATOM   516  C  CG  . ASP A 1 117 ? 141.844 150.587 172.026 1.00 64.44  ? 117  ASP A CG  1 
ATOM   517  O  OD1 . ASP A 1 117 ? 141.264 151.692 172.019 1.00 64.44  ? 117  ASP A OD1 1 
ATOM   518  O  OD2 . ASP A 1 117 ? 142.996 150.426 172.483 1.00 64.44  ? 117  ASP A OD2 1 
ATOM   519  N  N   . LEU A 1 118 ? 138.005 150.991 170.349 1.00 61.66  ? 118  LEU A N   1 
ATOM   520  C  CA  . LEU A 1 118 ? 137.406 151.639 169.189 1.00 61.66  ? 118  LEU A CA  1 
ATOM   521  C  C   . LEU A 1 118 ? 138.209 152.854 168.736 1.00 61.66  ? 118  LEU A C   1 
ATOM   522  O  O   . LEU A 1 118 ? 138.311 153.115 167.534 1.00 61.66  ? 118  LEU A O   1 
ATOM   523  C  CB  . LEU A 1 118 ? 135.962 152.038 169.495 1.00 61.66  ? 118  LEU A CB  1 
ATOM   524  C  CG  . LEU A 1 118 ? 135.721 152.990 170.669 1.00 61.66  ? 118  LEU A CG  1 
ATOM   525  C  CD1 . LEU A 1 118 ? 134.627 153.990 170.325 1.00 61.66  ? 118  LEU A CD1 1 
ATOM   526  C  CD2 . LEU A 1 118 ? 135.368 152.222 171.934 1.00 61.66  ? 118  LEU A CD2 1 
ATOM   527  N  N   . PHE A 1 119 ? 138.782 153.605 169.679 1.00 56.33  ? 119  PHE A N   1 
ATOM   528  C  CA  . PHE A 1 119 ? 139.452 154.855 169.329 1.00 56.33  ? 119  PHE A CA  1 
ATOM   529  C  C   . PHE A 1 119 ? 140.697 154.597 168.488 1.00 56.33  ? 119  PHE A C   1 
ATOM   530  O  O   . PHE A 1 119 ? 140.903 155.237 167.448 1.00 56.33  ? 119  PHE A O   1 
ATOM   531  C  CB  . PHE A 1 119 ? 139.808 155.623 170.602 1.00 56.33  ? 119  PHE A CB  1 
ATOM   532  C  CG  . PHE A 1 119 ? 140.425 156.971 170.353 1.00 56.33  ? 119  PHE A CG  1 
ATOM   533  C  CD1 . PHE A 1 119 ? 140.095 157.705 169.227 1.00 56.33  ? 119  PHE A CD1 1 
ATOM   534  C  CD2 . PHE A 1 119 ? 141.337 157.503 171.246 1.00 56.33  ? 119  PHE A CD2 1 
ATOM   535  C  CE1 . PHE A 1 119 ? 140.662 158.944 169.001 1.00 56.33  ? 119  PHE A CE1 1 
ATOM   536  C  CE2 . PHE A 1 119 ? 141.907 158.740 171.023 1.00 56.33  ? 119  PHE A CE2 1 
ATOM   537  C  CZ  . PHE A 1 119 ? 141.569 159.462 169.900 1.00 56.33  ? 119  PHE A CZ  1 
ATOM   538  N  N   . ALA A 1 120 ? 141.546 153.668 168.931 1.00 57.34  ? 120  ALA A N   1 
ATOM   539  C  CA  . ALA A 1 120 ? 142.758 153.360 168.183 1.00 57.34  ? 120  ALA A CA  1 
ATOM   540  C  C   . ALA A 1 120 ? 142.426 152.793 166.811 1.00 57.34  ? 120  ALA A C   1 
ATOM   541  O  O   . ALA A 1 120 ? 143.067 153.145 165.813 1.00 57.34  ? 120  ALA A O   1 
ATOM   542  C  CB  . ALA A 1 120 ? 143.629 152.383 168.972 1.00 57.34  ? 120  ALA A CB  1 
ATOM   543  N  N   . ALA A 1 121 ? 141.426 151.913 166.741 1.00 58.53  ? 121  ALA A N   1 
ATOM   544  C  CA  . ALA A 1 121 ? 141.029 151.352 165.456 1.00 58.53  ? 121  ALA A CA  1 
ATOM   545  C  C   . ALA A 1 121 ? 140.526 152.439 164.517 1.00 58.53  ? 121  ALA A C   1 
ATOM   546  O  O   . ALA A 1 121 ? 140.844 152.433 163.324 1.00 58.53  ? 121  ALA A O   1 
ATOM   547  C  CB  . ALA A 1 121 ? 139.964 150.277 165.659 1.00 58.53  ? 121  ALA A CB  1 
ATOM   548  N  N   . GLY A 1 122 ? 139.745 153.385 165.039 1.00 57.34  ? 122  GLY A N   1 
ATOM   549  C  CA  . GLY A 1 122 ? 139.267 154.475 164.206 1.00 57.34  ? 122  GLY A CA  1 
ATOM   550  C  C   . GLY A 1 122 ? 140.389 155.364 163.705 1.00 57.34  ? 122  GLY A C   1 
ATOM   551  O  O   . GLY A 1 122 ? 140.391 155.782 162.545 1.00 57.34  ? 122  GLY A O   1 
ATOM   552  N  N   . VAL A 1 123 ? 141.357 155.667 164.572 1.00 53.88  ? 123  VAL A N   1 
ATOM   553  C  CA  . VAL A 1 123 ? 142.488 156.491 164.150 1.00 53.88  ? 123  VAL A CA  1 
ATOM   554  C  C   . VAL A 1 123 ? 143.300 155.774 163.078 1.00 53.88  ? 123  VAL A C   1 
ATOM   555  O  O   . VAL A 1 123 ? 143.725 156.381 162.087 1.00 53.88  ? 123  VAL A O   1 
ATOM   556  C  CB  . VAL A 1 123 ? 143.357 156.876 165.360 1.00 53.88  ? 123  VAL A CB  1 
ATOM   557  C  CG1 . VAL A 1 123 ? 144.633 157.558 164.902 1.00 53.88  ? 123  VAL A CG1 1 
ATOM   558  C  CG2 . VAL A 1 123 ? 142.582 157.785 166.289 1.00 53.88  ? 123  VAL A CG2 1 
ATOM   559  N  N   . ILE A 1 124 ? 143.528 154.471 163.258 1.00 55.12  ? 124  ILE A N   1 
ATOM   560  C  CA  . ILE A 1 124 ? 144.268 153.706 162.259 1.00 55.12  ? 124  ILE A CA  1 
ATOM   561  C  C   . ILE A 1 124 ? 143.501 153.663 160.945 1.00 55.12  ? 124  ILE A C   1 
ATOM   562  O  O   . ILE A 1 124 ? 144.089 153.755 159.860 1.00 55.12  ? 124  ILE A O   1 
ATOM   563  C  CB  . ILE A 1 124 ? 144.577 152.294 162.791 1.00 55.12  ? 124  ILE A CB  1 
ATOM   564  C  CG1 . ILE A 1 124 ? 145.799 152.330 163.707 1.00 55.12  ? 124  ILE A CG1 1 
ATOM   565  C  CG2 . ILE A 1 124 ? 144.810 151.324 161.655 1.00 55.12  ? 124  ILE A CG2 1 
ATOM   566  C  CD1 . ILE A 1 124 ? 146.110 151.005 164.354 1.00 55.12  ? 124  ILE A CD1 1 
ATOM   567  N  N   . ALA A 1 125 ? 142.176 153.526 161.017 1.00 53.94  ? 125  ALA A N   1 
ATOM   568  C  CA  . ALA A 1 125 ? 141.367 153.532 159.803 1.00 53.94  ? 125  ALA A CA  1 
ATOM   569  C  C   . ALA A 1 125 ? 141.461 154.872 159.087 1.00 53.94  ? 125  ALA A C   1 
ATOM   570  O  O   . ALA A 1 125 ? 141.555 154.920 157.856 1.00 53.94  ? 125  ALA A O   1 
ATOM   571  C  CB  . ALA A 1 125 ? 139.915 153.200 160.139 1.00 53.94  ? 125  ALA A CB  1 
ATOM   572  N  N   . LEU A 1 126 ? 141.434 155.973 159.838 1.00 53.22  ? 126  LEU A N   1 
ATOM   573  C  CA  . LEU A 1 126 ? 141.583 157.284 159.217 1.00 53.22  ? 126  LEU A CA  1 
ATOM   574  C  C   . LEU A 1 126 ? 142.952 157.430 158.564 1.00 53.22  ? 126  LEU A C   1 
ATOM   575  O  O   . LEU A 1 126 ? 143.068 157.974 157.458 1.00 53.22  ? 126  LEU A O   1 
ATOM   576  C  CB  . LEU A 1 126 ? 141.359 158.386 160.250 1.00 53.22  ? 126  LEU A CB  1 
ATOM   577  C  CG  . LEU A 1 126 ? 141.591 159.818 159.767 1.00 53.22  ? 126  LEU A CG  1 
ATOM   578  C  CD1 . LEU A 1 126 ? 140.733 160.120 158.550 1.00 53.22  ? 126  LEU A CD1 1 
ATOM   579  C  CD2 . LEU A 1 126 ? 141.303 160.807 160.883 1.00 53.22  ? 126  LEU A CD2 1 
ATOM   580  N  N   . MET A 1 127 ? 144.002 156.947 159.233 1.00 54.69  ? 127  MET A N   1 
ATOM   581  C  CA  . MET A 1 127 ? 145.340 157.017 158.654 1.00 54.69  ? 127  MET A CA  1 
ATOM   582  C  C   . MET A 1 127 ? 145.426 156.213 157.363 1.00 54.69  ? 127  MET A C   1 
ATOM   583  O  O   . MET A 1 127 ? 145.984 156.684 156.364 1.00 54.69  ? 127  MET A O   1 
ATOM   584  C  CB  . MET A 1 127 ? 146.377 156.520 159.661 1.00 54.69  ? 127  MET A CB  1 
ATOM   585  C  CG  . MET A 1 127 ? 146.794 157.523 160.738 1.00 54.69  ? 127  MET A CG  1 
ATOM   586  S  SD  . MET A 1 127 ? 147.157 159.201 160.174 1.00 54.69  ? 127  MET A SD  1 
ATOM   587  C  CE  . MET A 1 127 ? 145.575 160.021 160.372 1.00 54.69  ? 127  MET A CE  1 
ATOM   588  N  N   . VAL A 1 128 ? 144.870 155.000 157.359 1.00 53.05  ? 128  VAL A N   1 
ATOM   589  C  CA  . VAL A 1 128 ? 144.940 154.171 156.161 1.00 53.05  ? 128  VAL A CA  1 
ATOM   590  C  C   . VAL A 1 128 ? 144.085 154.762 155.046 1.00 53.05  ? 128  VAL A C   1 
ATOM   591  O  O   . VAL A 1 128 ? 144.440 154.658 153.868 1.00 53.05  ? 128  VAL A O   1 
ATOM   592  C  CB  . VAL A 1 128 ? 144.559 152.711 156.478 1.00 53.05  ? 128  VAL A CB  1 
ATOM   593  C  CG1 . VAL A 1 128 ? 143.058 152.530 156.555 1.00 53.05  ? 128  VAL A CG1 1 
ATOM   594  C  CG2 . VAL A 1 128 ? 145.146 151.777 155.439 1.00 53.05  ? 128  VAL A CG2 1 
ATOM   595  N  N   . ALA A 1 129 ? 142.964 155.405 155.385 1.00 54.86  ? 129  ALA A N   1 
ATOM   596  C  CA  . ALA A 1 129 ? 142.149 156.049 154.360 1.00 54.86  ? 129  ALA A CA  1 
ATOM   597  C  C   . ALA A 1 129 ? 142.874 157.238 153.743 1.00 54.86  ? 129  ALA A C   1 
ATOM   598  O  O   . ALA A 1 129 ? 142.821 157.439 152.524 1.00 54.86  ? 129  ALA A O   1 
ATOM   599  C  CB  . ALA A 1 129 ? 140.810 156.485 154.950 1.00 54.86  ? 129  ALA A CB  1 
ATOM   600  N  N   . ILE A 1 130 ? 143.552 158.038 154.569 1.00 54.89  ? 130  ILE A N   1 
ATOM   601  C  CA  . ILE A 1 130 ? 144.332 159.154 154.041 1.00 54.89  ? 130  ILE A CA  1 
ATOM   602  C  C   . ILE A 1 130 ? 145.448 158.635 153.146 1.00 54.89  ? 130  ILE A C   1 
ATOM   603  O  O   . ILE A 1 130 ? 145.711 159.186 152.069 1.00 54.89  ? 130  ILE A O   1 
ATOM   604  C  CB  . ILE A 1 130 ? 144.879 160.018 155.191 1.00 54.89  ? 130  ILE A CB  1 
ATOM   605  C  CG1 . ILE A 1 130 ? 143.840 161.050 155.623 1.00 54.89  ? 130  ILE A CG1 1 
ATOM   606  C  CG2 . ILE A 1 130 ? 146.153 160.724 154.771 1.00 54.89  ? 130  ILE A CG2 1 
ATOM   607  C  CD1 . ILE A 1 130 ? 144.381 162.099 156.571 1.00 54.89  ? 130  ILE A CD1 1 
ATOM   608  N  N   . SER A 1 131 ? 146.115 157.560 153.575 1.00 52.85  ? 131  SER A N   1 
ATOM   609  C  CA  . SER A 1 131 ? 147.161 156.961 152.754 1.00 52.85  ? 131  SER A CA  1 
ATOM   610  C  C   . SER A 1 131 ? 146.606 156.474 151.424 1.00 52.85  ? 131  SER A C   1 
ATOM   611  O  O   . SER A 1 131 ? 147.227 156.673 150.375 1.00 52.85  ? 131  SER A O   1 
ATOM   612  C  CB  . SER A 1 131 ? 147.821 155.807 153.505 1.00 52.85  ? 131  SER A CB  1 
ATOM   613  O  OG  . SER A 1 131 ? 148.606 155.020 152.630 1.00 52.85  ? 131  SER A OG  1 
ATOM   614  N  N   . THR A 1 132 ? 145.437 155.834 151.450 1.00 60.21  ? 132  THR A N   1 
ATOM   615  C  CA  . THR A 1 132 ? 144.842 155.330 150.218 1.00 60.21  ? 132  THR A CA  1 
ATOM   616  C  C   . THR A 1 132 ? 144.465 156.468 149.278 1.00 60.21  ? 132  THR A C   1 
ATOM   617  O  O   . THR A 1 132 ? 144.703 156.382 148.071 1.00 60.21  ? 132  THR A O   1 
ATOM   618  C  CB  . THR A 1 132 ? 143.625 154.464 150.541 1.00 60.21  ? 132  THR A CB  1 
ATOM   619  O  OG1 . THR A 1 132 ? 144.057 153.257 151.180 1.00 60.21  ? 132  THR A OG1 1 
ATOM   620  C  CG2 . THR A 1 132 ? 142.875 154.105 149.275 1.00 60.21  ? 132  THR A CG2 1 
ATOM   621  N  N   . LEU A 1 133 ? 143.886 157.547 149.807 1.00 65.15  ? 133  LEU A N   1 
ATOM   622  C  CA  . LEU A 1 133 ? 143.527 158.677 148.952 1.00 65.15  ? 133  LEU A CA  1 
ATOM   623  C  C   . LEU A 1 133 ? 144.761 159.343 148.354 1.00 65.15  ? 133  LEU A C   1 
ATOM   624  O  O   . LEU A 1 133 ? 144.760 159.725 147.175 1.00 65.15  ? 133  LEU A O   1 
ATOM   625  C  CB  . LEU A 1 133 ? 142.701 159.693 149.739 1.00 65.15  ? 133  LEU A CB  1 
ATOM   626  C  CG  . LEU A 1 133 ? 141.188 159.644 149.523 1.00 65.15  ? 133  LEU A CG  1 
ATOM   627  C  CD1 . LEU A 1 133 ? 140.606 158.336 150.031 1.00 65.15  ? 133  LEU A CD1 1 
ATOM   628  C  CD2 . LEU A 1 133 ? 140.518 160.828 150.200 1.00 65.15  ? 133  LEU A CD2 1 
ATOM   629  N  N   . LEU A 1 134 ? 145.816 159.510 149.156 1.00 64.52  ? 134  LEU A N   1 
ATOM   630  C  CA  . LEU A 1 134 ? 147.052 160.096 148.645 1.00 64.52  ? 134  LEU A CA  1 
ATOM   631  C  C   . LEU A 1 134 ? 147.670 159.215 147.566 1.00 64.52  ? 134  LEU A C   1 
ATOM   632  O  O   . LEU A 1 134 ? 148.110 159.707 146.517 1.00 64.52  ? 134  LEU A O   1 
ATOM   633  C  CB  . LEU A 1 134 ? 148.025 160.315 149.803 1.00 64.52  ? 134  LEU A CB  1 
ATOM   634  C  CG  . LEU A 1 134 ? 149.430 160.831 149.515 1.00 64.52  ? 134  LEU A CG  1 
ATOM   635  C  CD1 . LEU A 1 134 ? 149.797 161.891 150.530 1.00 64.52  ? 134  LEU A CD1 1 
ATOM   636  C  CD2 . LEU A 1 134 ? 150.425 159.688 149.563 1.00 64.52  ? 134  LEU A CD2 1 
ATOM   637  N  N   . ASN A 1 135 ? 147.696 157.903 147.800 1.00 71.00  ? 135  ASN A N   1 
ATOM   638  C  CA  . ASN A 1 135 ? 148.192 156.982 146.790 1.00 71.00  ? 135  ASN A CA  1 
ATOM   639  C  C   . ASN A 1 135 ? 147.306 157.035 145.551 1.00 71.00  ? 135  ASN A C   1 
ATOM   640  O  O   . ASN A 1 135 ? 147.795 156.903 144.429 1.00 71.00  ? 135  ASN A O   1 
ATOM   641  C  CB  . ASN A 1 135 ? 148.258 155.573 147.392 1.00 71.00  ? 135  ASN A CB  1 
ATOM   642  C  CG  . ASN A 1 135 ? 148.823 154.527 146.440 1.00 71.00  ? 135  ASN A CG  1 
ATOM   643  O  OD1 . ASN A 1 135 ? 148.995 154.758 145.246 1.00 71.00  ? 135  ASN A OD1 1 
ATOM   644  N  ND2 . ASN A 1 135 ? 149.114 153.352 146.984 1.00 71.00  ? 135  ASN A ND2 1 
ATOM   645  N  N   . PHE A 1 136 ? 146.006 157.278 145.734 1.00 76.46  ? 136  PHE A N   1 
ATOM   646  C  CA  . PHE A 1 136 ? 145.083 157.348 144.605 1.00 76.46  ? 136  PHE A CA  1 
ATOM   647  C  C   . PHE A 1 136 ? 145.385 158.545 143.715 1.00 76.46  ? 136  PHE A C   1 
ATOM   648  O  O   . PHE A 1 136 ? 145.467 158.415 142.489 1.00 76.46  ? 136  PHE A O   1 
ATOM   649  C  CB  . PHE A 1 136 ? 143.641 157.396 145.120 1.00 76.46  ? 136  PHE A CB  1 
ATOM   650  C  CG  . PHE A 1 136 ? 142.693 158.163 144.234 1.00 76.46  ? 136  PHE A CG  1 
ATOM   651  C  CD1 . PHE A 1 136 ? 142.020 157.526 143.205 1.00 76.46  ? 136  PHE A CD1 1 
ATOM   652  C  CD2 . PHE A 1 136 ? 142.441 159.509 144.458 1.00 76.46  ? 136  PHE A CD2 1 
ATOM   653  C  CE1 . PHE A 1 136 ? 141.141 158.221 142.397 1.00 76.46  ? 136  PHE A CE1 1 
ATOM   654  C  CE2 . PHE A 1 136 ? 141.565 160.208 143.653 1.00 76.46  ? 136  PHE A CE2 1 
ATOM   655  C  CZ  . PHE A 1 136 ? 140.913 159.564 142.623 1.00 76.46  ? 136  PHE A CZ  1 
ATOM   656  N  N   . ILE A 1 137 ? 145.541 159.728 144.313 1.00 77.99  ? 137  ILE A N   1 
ATOM   657  C  CA  . ILE A 1 137 ? 145.825 160.911 143.501 1.00 77.99  ? 137  ILE A CA  1 
ATOM   658  C  C   . ILE A 1 137 ? 147.190 160.775 142.836 1.00 77.99  ? 137  ILE A C   1 
ATOM   659  O  O   . ILE A 1 137 ? 147.361 161.094 141.650 1.00 77.99  ? 137  ILE A O   1 
ATOM   660  C  CB  . ILE A 1 137 ? 145.717 162.202 144.337 1.00 77.99  ? 137  ILE A CB  1 
ATOM   661  C  CG1 . ILE A 1 137 ? 146.389 163.368 143.613 1.00 77.99  ? 137  ILE A CG1 1 
ATOM   662  C  CG2 . ILE A 1 137 ? 146.343 162.038 145.694 1.00 77.99  ? 137  ILE A CG2 1 
ATOM   663  C  CD1 . ILE A 1 137 ? 146.212 164.699 144.307 1.00 77.99  ? 137  ILE A CD1 1 
ATOM   664  N  N   . GLN A 1 138 ? 148.178 160.266 143.580 1.00 82.57  ? 138  GLN A N   1 
ATOM   665  C  CA  . GLN A 1 138 ? 149.499 160.077 142.994 1.00 82.57  ? 138  GLN A CA  1 
ATOM   666  C  C   . GLN A 1 138 ? 149.476 159.060 141.856 1.00 82.57  ? 138  GLN A C   1 
ATOM   667  O  O   . GLN A 1 138 ? 150.160 159.247 140.845 1.00 82.57  ? 138  GLN A O   1 
ATOM   668  C  CB  . GLN A 1 138 ? 150.486 159.646 144.072 1.00 82.57  ? 138  GLN A CB  1 
ATOM   669  C  CG  . GLN A 1 138 ? 151.905 159.489 143.583 1.00 82.57  ? 138  GLN A CG  1 
ATOM   670  C  CD  . GLN A 1 138 ? 152.617 158.362 144.287 1.00 82.57  ? 138  GLN A CD  1 
ATOM   671  O  OE1 . GLN A 1 138 ? 152.900 158.448 145.478 1.00 82.57  ? 138  GLN A OE1 1 
ATOM   672  N  NE2 . GLN A 1 138 ? 152.911 157.294 143.556 1.00 82.57  ? 138  GLN A NE2 1 
ATOM   673  N  N   . GLU A 1 139 ? 148.692 157.990 141.991 1.00 88.44  ? 139  GLU A N   1 
ATOM   674  C  CA  . GLU A 1 139 ? 148.611 156.976 140.949 1.00 88.44  ? 139  GLU A CA  1 
ATOM   675  C  C   . GLU A 1 139 ? 147.849 157.485 139.734 1.00 88.44  ? 139  GLU A C   1 
ATOM   676  O  O   . GLU A 1 139 ? 148.157 157.097 138.605 1.00 88.44  ? 139  GLU A O   1 
ATOM   677  C  CB  . GLU A 1 139 ? 147.955 155.709 141.498 1.00 88.44  ? 139  GLU A CB  1 
ATOM   678  N  N   . ALA A 1 140 ? 146.848 158.342 139.943 1.00 94.63  ? 140  ALA A N   1 
ATOM   679  C  CA  . ALA A 1 140 ? 146.202 158.994 138.809 1.00 94.63  ? 140  ALA A CA  1 
ATOM   680  C  C   . ALA A 1 140 ? 147.193 159.869 138.056 1.00 94.63  ? 140  ALA A C   1 
ATOM   681  O  O   . ALA A 1 140 ? 147.229 159.865 136.818 1.00 94.63  ? 140  ALA A O   1 
ATOM   682  C  CB  . ALA A 1 140 ? 145.006 159.819 139.282 1.00 94.63  ? 140  ALA A CB  1 
ATOM   683  N  N   . ARG A 1 141 ? 148.022 160.615 138.791 1.00 98.78  ? 141  ARG A N   1 
ATOM   684  C  CA  . ARG A 1 141 ? 149.063 161.407 138.143 1.00 98.78  ? 141  ARG A CA  1 
ATOM   685  C  C   . ARG A 1 141 ? 150.044 160.515 137.388 1.00 98.78  ? 141  ARG A C   1 
ATOM   686  O  O   . ARG A 1 141 ? 150.471 160.849 136.277 1.00 98.78  ? 141  ARG A O   1 
ATOM   687  C  CB  . ARG A 1 141 ? 149.797 162.262 139.177 1.00 98.78  ? 141  ARG A CB  1 
ATOM   688  N  N   . SER A 1 142 ? 150.414 159.378 137.980 1.00 102.28 ? 142  SER A N   1 
ATOM   689  C  CA  . SER A 1 142 ? 151.330 158.455 137.314 1.00 102.28 ? 142  SER A CA  1 
ATOM   690  C  C   . SER A 1 142 ? 150.717 157.885 136.040 1.00 102.28 ? 142  SER A C   1 
ATOM   691  O  O   . SER A 1 142 ? 151.393 157.785 135.010 1.00 102.28 ? 142  SER A O   1 
ATOM   692  C  CB  . SER A 1 142 ? 151.720 157.324 138.265 1.00 102.28 ? 142  SER A CB  1 
ATOM   693  O  OG  . SER A 1 142 ? 150.628 156.450 138.491 1.00 102.28 ? 142  SER A OG  1 
ATOM   694  N  N   . THR A 1 143 ? 149.441 157.497 136.098 1.00 110.73 ? 143  THR A N   1 
ATOM   695  C  CA  . THR A 1 143 ? 148.762 156.978 134.917 1.00 110.73 ? 143  THR A CA  1 
ATOM   696  C  C   . THR A 1 143 ? 148.670 158.041 133.832 1.00 110.73 ? 143  THR A C   1 
ATOM   697  O  O   . THR A 1 143 ? 148.751 157.730 132.638 1.00 110.73 ? 143  THR A O   1 
ATOM   698  C  CB  . THR A 1 143 ? 147.369 156.470 135.290 1.00 110.73 ? 143  THR A CB  1 
ATOM   699  N  N   . LYS A 1 144 ? 148.490 159.302 134.229 1.00 112.57 ? 144  LYS A N   1 
ATOM   700  C  CA  . LYS A 1 144 ? 148.584 160.388 133.261 1.00 112.57 ? 144  LYS A CA  1 
ATOM   701  C  C   . LYS A 1 144 ? 149.984 160.459 132.662 1.00 112.57 ? 144  LYS A C   1 
ATOM   702  O  O   . LYS A 1 144 ? 150.142 160.675 131.454 1.00 112.57 ? 144  LYS A O   1 
ATOM   703  C  CB  . LYS A 1 144 ? 148.210 161.715 133.920 1.00 112.57 ? 144  LYS A CB  1 
ATOM   704  N  N   . ALA A 1 145 ? 151.012 160.277 133.495 1.00 113.48 ? 145  ALA A N   1 
ATOM   705  C  CA  . ALA A 1 145 ? 152.386 160.290 133.001 1.00 113.48 ? 145  ALA A CA  1 
ATOM   706  C  C   . ALA A 1 145 ? 152.724 159.003 132.258 1.00 113.48 ? 145  ALA A C   1 
ATOM   707  O  O   . ALA A 1 145 ? 153.411 159.035 131.230 1.00 113.48 ? 145  ALA A O   1 
ATOM   708  C  CB  . ALA A 1 145 ? 153.357 160.513 134.160 1.00 113.48 ? 145  ALA A CB  1 
ATOM   709  N  N   . ALA A 1 146 ? 152.257 157.862 132.760 1.00 122.05 ? 146  ALA A N   1 
ATOM   710  C  CA  . ALA A 1 146 ? 152.529 156.555 132.163 1.00 122.05 ? 146  ALA A CA  1 
ATOM   711  C  C   . ALA A 1 146 ? 151.193 155.864 131.904 1.00 122.05 ? 146  ALA A C   1 
ATOM   712  O  O   . ALA A 1 146 ? 150.698 155.109 132.744 1.00 122.05 ? 146  ALA A O   1 
ATOM   713  C  CB  . ALA A 1 146 ? 153.431 155.716 133.068 1.00 122.05 ? 146  ALA A CB  1 
ATOM   714  N  N   . ASP A 1 147 ? 150.610 156.126 130.733 1.00 136.91 ? 147  ASP A N   1 
ATOM   715  C  CA  . ASP A 1 147 ? 149.333 155.509 130.389 1.00 136.91 ? 147  ASP A CA  1 
ATOM   716  C  C   . ASP A 1 147 ? 149.504 154.027 130.076 1.00 136.91 ? 147  ASP A C   1 
ATOM   717  O  O   . ASP A 1 147 ? 148.734 153.188 130.559 1.00 136.91 ? 147  ASP A O   1 
ATOM   718  C  CB  . ASP A 1 147 ? 148.700 156.241 129.206 1.00 136.91 ? 147  ASP A CB  1 
ATOM   719  N  N   . ALA A 1 148 ? 150.511 153.686 129.277 1.00 158.14 ? 148  ALA A N   1 
ATOM   720  C  CA  . ALA A 1 148 ? 150.752 152.305 128.882 1.00 158.14 ? 148  ALA A CA  1 
ATOM   721  C  C   . ALA A 1 148 ? 152.164 152.199 128.325 1.00 158.14 ? 148  ALA A C   1 
ATOM   722  O  O   . ALA A 1 148 ? 152.878 153.196 128.193 1.00 158.14 ? 148  ALA A O   1 
ATOM   723  C  CB  . ALA A 1 148 ? 149.722 151.825 127.854 1.00 158.14 ? 148  ALA A CB  1 
ATOM   724  N  N   . LEU A 1 149 ? 152.562 150.965 128.007 1.00 172.22 ? 149  LEU A N   1 
ATOM   725  C  CA  . LEU A 1 149 ? 153.867 150.746 127.394 1.00 172.22 ? 149  LEU A CA  1 
ATOM   726  C  C   . LEU A 1 149 ? 153.954 151.422 126.031 1.00 172.22 ? 149  LEU A C   1 
ATOM   727  O  O   . LEU A 1 149 ? 154.970 152.042 125.699 1.00 172.22 ? 149  LEU A O   1 
ATOM   728  C  CB  . LEU A 1 149 ? 154.145 149.248 127.271 1.00 172.22 ? 149  LEU A CB  1 
ATOM   729  N  N   . LYS A 1 150 ? 152.898 151.313 125.230 1.00 179.84 ? 150  LYS A N   1 
ATOM   730  C  CA  . LYS A 1 150 ? 152.816 151.966 123.933 1.00 179.84 ? 150  LYS A CA  1 
ATOM   731  C  C   . LYS A 1 150 ? 151.552 152.811 123.872 1.00 179.84 ? 150  LYS A C   1 
ATOM   732  O  O   . LYS A 1 150 ? 150.480 152.372 124.302 1.00 179.84 ? 150  LYS A O   1 
ATOM   733  C  CB  . LYS A 1 150 ? 152.819 150.942 122.793 1.00 179.84 ? 150  LYS A CB  1 
ATOM   734  N  N   . ALA A 1 151 ? 151.686 154.030 123.345 1.00 189.78 ? 151  ALA A N   1 
ATOM   735  C  CA  . ALA A 1 151 ? 150.533 154.917 123.229 1.00 189.78 ? 151  ALA A CA  1 
ATOM   736  C  C   . ALA A 1 151 ? 149.487 154.337 122.285 1.00 189.78 ? 151  ALA A C   1 
ATOM   737  O  O   . ALA A 1 151 ? 148.283 154.396 122.563 1.00 189.78 ? 151  ALA A O   1 
ATOM   738  C  CB  . ALA A 1 151 ? 150.981 156.300 122.757 1.00 189.78 ? 151  ALA A CB  1 
ATOM   739  N  N   . MET A 1 152 ? 149.933 153.795 121.149 1.00 196.04 ? 152  MET A N   1 
ATOM   740  C  CA  . MET A 1 152 ? 149.075 153.142 120.162 1.00 196.04 ? 152  MET A CA  1 
ATOM   741  C  C   . MET A 1 152 ? 148.082 154.114 119.531 1.00 196.04 ? 152  MET A C   1 
ATOM   742  O  O   . MET A 1 152 ? 147.258 153.712 118.703 1.00 196.04 ? 152  MET A O   1 
ATOM   743  C  CB  . MET A 1 152 ? 148.332 151.958 120.789 1.00 196.04 ? 152  MET A CB  1 
ATOM   744  N  N   . VAL A 1 153 ? 148.154 155.387 119.907 1.00 200.18 ? 153  VAL A N   1 
ATOM   745  C  CA  . VAL A 1 153 ? 147.277 156.412 119.361 1.00 200.18 ? 153  VAL A CA  1 
ATOM   746  C  C   . VAL A 1 153 ? 148.003 157.289 118.349 1.00 200.18 ? 153  VAL A C   1 
ATOM   747  O  O   . VAL A 1 153 ? 147.485 157.543 117.262 1.00 200.18 ? 153  VAL A O   1 
ATOM   748  C  CB  . VAL A 1 153 ? 146.676 157.262 120.501 1.00 200.18 ? 153  VAL A CB  1 
ATOM   749  N  N   . SER A 1 154 ? 149.205 157.757 118.693 1.00 202.08 ? 154  SER A N   1 
ATOM   750  C  CA  . SER A 1 154 ? 149.984 158.566 117.764 1.00 202.08 ? 154  SER A CA  1 
ATOM   751  C  C   . SER A 1 154 ? 150.562 157.740 116.624 1.00 202.08 ? 154  SER A C   1 
ATOM   752  O  O   . SER A 1 154 ? 150.986 158.312 115.615 1.00 202.08 ? 154  SER A O   1 
ATOM   753  C  CB  . SER A 1 154 ? 151.109 159.285 118.509 1.00 202.08 ? 154  SER A CB  1 
ATOM   754  N  N   . ASN A 1 155 ? 150.593 156.416 116.762 1.00 206.47 ? 155  ASN A N   1 
ATOM   755  C  CA  . ASN A 1 155 ? 151.096 155.563 115.695 1.00 206.47 ? 155  ASN A CA  1 
ATOM   756  C  C   . ASN A 1 155 ? 150.132 155.577 114.516 1.00 206.47 ? 155  ASN A C   1 
ATOM   757  O  O   . ASN A 1 155 ? 148.921 155.406 114.686 1.00 206.47 ? 155  ASN A O   1 
ATOM   758  C  CB  . ASN A 1 155 ? 151.292 154.136 116.205 1.00 206.47 ? 155  ASN A CB  1 
ATOM   759  N  N   . THR A 1 156 ? 150.673 155.780 113.317 1.00 212.92 ? 156  THR A N   1 
ATOM   760  C  CA  . THR A 1 156 ? 149.886 155.833 112.095 1.00 212.92 ? 156  THR A CA  1 
ATOM   761  C  C   . THR A 1 156 ? 150.502 154.896 111.062 1.00 212.92 ? 156  THR A C   1 
ATOM   762  O  O   . THR A 1 156 ? 151.496 154.212 111.323 1.00 212.92 ? 156  THR A O   1 
ATOM   763  C  CB  . THR A 1 156 ? 149.800 157.264 111.549 1.00 212.92 ? 156  THR A CB  1 
ATOM   764  N  N   . ALA A 1 157 ? 149.900 154.870 109.875 1.00 218.62 ? 157  ALA A N   1 
ATOM   765  C  CA  . ALA A 1 157 ? 150.372 154.032 108.785 1.00 218.62 ? 157  ALA A CA  1 
ATOM   766  C  C   . ALA A 1 157 ? 150.402 154.847 107.501 1.00 218.62 ? 157  ALA A C   1 
ATOM   767  O  O   . ALA A 1 157 ? 149.615 155.779 107.320 1.00 218.62 ? 157  ALA A O   1 
ATOM   768  C  CB  . ALA A 1 157 ? 149.490 152.790 108.601 1.00 218.62 ? 157  ALA A CB  1 
ATOM   769  N  N   . THR A 1 158 ? 151.321 154.483 106.610 1.00 222.79 ? 158  THR A N   1 
ATOM   770  C  CA  . THR A 1 158 ? 151.479 155.147 105.322 1.00 222.79 ? 158  THR A CA  1 
ATOM   771  C  C   . THR A 1 158 ? 150.721 154.343 104.271 1.00 222.79 ? 158  THR A C   1 
ATOM   772  O  O   . THR A 1 158 ? 151.118 153.224 103.932 1.00 222.79 ? 158  THR A O   1 
ATOM   773  C  CB  . THR A 1 158 ? 152.954 155.281 104.952 1.00 222.79 ? 158  THR A CB  1 
ATOM   774  N  N   . VAL A 1 159 ? 149.635 154.916 103.756 1.00 225.99 ? 159  VAL A N   1 
ATOM   775  C  CA  . VAL A 1 159 ? 148.800 154.256 102.764 1.00 225.99 ? 159  VAL A CA  1 
ATOM   776  C  C   . VAL A 1 159 ? 148.710 155.143 101.530 1.00 225.99 ? 159  VAL A C   1 
ATOM   777  O  O   . VAL A 1 159 ? 148.870 156.364 101.595 1.00 225.99 ? 159  VAL A O   1 
ATOM   778  C  CB  . VAL A 1 159 ? 147.392 153.936 103.307 1.00 225.99 ? 159  VAL A CB  1 
ATOM   779  N  N   . LEU A 1 160 ? 148.448 154.505 100.388 1.00 228.09 ? 160  LEU A N   1 
ATOM   780  C  CA  . LEU A 1 160 ? 148.368 155.241 99.130  1.00 228.09 ? 160  LEU A CA  1 
ATOM   781  C  C   . LEU A 1 160 ? 147.067 156.029 99.041  1.00 228.09 ? 160  LEU A C   1 
ATOM   782  O  O   . LEU A 1 160 ? 147.079 157.263 98.951  1.00 228.09 ? 160  LEU A O   1 
ATOM   783  C  CB  . LEU A 1 160 ? 148.501 154.276 97.950  1.00 228.09 ? 160  LEU A CB  1 
ATOM   784  N  N   . ARG A 1 161 ? 145.931 155.327 99.074  1.00 229.03 ? 161  ARG A N   1 
ATOM   785  C  CA  . ARG A 1 161 ? 144.607 155.942 99.028  1.00 229.03 ? 161  ARG A CA  1 
ATOM   786  C  C   . ARG A 1 161 ? 144.452 156.874 97.831  1.00 229.03 ? 161  ARG A C   1 
ATOM   787  O  O   . ARG A 1 161 ? 145.185 156.759 96.844  1.00 229.03 ? 161  ARG A O   1 
ATOM   788  C  CB  . ARG A 1 161 ? 144.324 156.700 100.328 1.00 229.03 ? 161  ARG A CB  1 
ATOM   789  N  N   . VAL A 1 162 ? 143.489 157.792 97.907  1.00 230.28 ? 162  VAL A N   1 
ATOM   790  C  CA  . VAL A 1 162 ? 143.290 158.792 96.865  1.00 230.28 ? 162  VAL A CA  1 
ATOM   791  C  C   . VAL A 1 162 ? 143.041 160.144 97.519  1.00 230.28 ? 162  VAL A C   1 
ATOM   792  O  O   . VAL A 1 162 ? 141.915 160.451 97.926  1.00 230.28 ? 162  VAL A O   1 
ATOM   793  C  CB  . VAL A 1 162 ? 142.129 158.406 95.930  1.00 230.28 ? 162  VAL A CB  1 
ATOM   794  N  N   . ILE A 1 163 ? 144.091 160.960 97.625  1.00 230.40 ? 163  ILE A N   1 
ATOM   795  C  CA  . ILE A 1 163 ? 143.959 162.266 98.264  1.00 230.40 ? 163  ILE A CA  1 
ATOM   796  C  C   . ILE A 1 163 ? 143.101 163.193 97.411  1.00 230.40 ? 163  ILE A C   1 
ATOM   797  O  O   . ILE A 1 163 ? 142.196 163.868 97.915  1.00 230.40 ? 163  ILE A O   1 
ATOM   798  C  CB  . ILE A 1 163 ? 145.346 162.872 98.537  1.00 230.40 ? 163  ILE A CB  1 
ATOM   799  N  N   . ASN A 1 164 ? 143.372 163.238 96.105  1.00 232.55 ? 164  ASN A N   1 
ATOM   800  C  CA  . ASN A 1 164 ? 142.624 164.123 95.219  1.00 232.55 ? 164  ASN A CA  1 
ATOM   801  C  C   . ASN A 1 164 ? 141.289 163.528 94.792  1.00 232.55 ? 164  ASN A C   1 
ATOM   802  O  O   . ASN A 1 164 ? 140.492 164.226 94.157  1.00 232.55 ? 164  ASN A O   1 
ATOM   803  C  CB  . ASN A 1 164 ? 143.460 164.460 93.984  1.00 232.55 ? 164  ASN A CB  1 
ATOM   804  N  N   . ASP A 1 165 ? 141.036 162.258 95.113  1.00 231.37 ? 165  ASP A N   1 
ATOM   805  C  CA  . ASP A 1 165 ? 139.813 161.533 94.776  1.00 231.37 ? 165  ASP A CA  1 
ATOM   806  C  C   . ASP A 1 165 ? 139.596 161.406 93.274  1.00 231.37 ? 165  ASP A C   1 
ATOM   807  O  O   . ASP A 1 165 ? 138.487 161.063 92.843  1.00 231.37 ? 165  ASP A O   1 
ATOM   808  C  CB  . ASP A 1 165 ? 138.576 162.171 95.419  1.00 231.37 ? 165  ASP A CB  1 
ATOM   809  N  N   . LYS A 1 166 ? 140.619 161.674 92.462  1.00 232.40 ? 166  LYS A N   1 
ATOM   810  C  CA  . LYS A 1 166 ? 140.520 161.565 91.011  1.00 232.40 ? 166  LYS A CA  1 
ATOM   811  C  C   . LYS A 1 166 ? 141.571 160.631 90.425  1.00 232.40 ? 166  LYS A C   1 
ATOM   812  O  O   . LYS A 1 166 ? 141.861 160.717 89.226  1.00 232.40 ? 166  LYS A O   1 
ATOM   813  C  CB  . LYS A 1 166 ? 140.631 162.949 90.365  1.00 232.40 ? 166  LYS A CB  1 
ATOM   814  N  N   . GLY A 1 167 ? 142.148 159.746 91.234  1.00 233.70 ? 167  GLY A N   1 
ATOM   815  C  CA  . GLY A 1 167 ? 143.192 158.854 90.779  1.00 233.70 ? 167  GLY A CA  1 
ATOM   816  C  C   . GLY A 1 167 ? 144.602 159.372 90.953  1.00 233.70 ? 167  GLY A C   1 
ATOM   817  O  O   . GLY A 1 167 ? 145.553 158.642 90.646  1.00 233.70 ? 167  GLY A O   1 
ATOM   818  N  N   . GLU A 1 168 ? 144.770 160.607 91.432  1.00 232.53 ? 168  GLU A N   1 
ATOM   819  C  CA  . GLU A 1 168 ? 146.111 161.142 91.644  1.00 232.53 ? 168  GLU A CA  1 
ATOM   820  C  C   . GLU A 1 168 ? 146.831 160.426 92.779  1.00 232.53 ? 168  GLU A C   1 
ATOM   821  O  O   . GLU A 1 168 ? 148.057 160.275 92.732  1.00 232.53 ? 168  GLU A O   1 
ATOM   822  C  CB  . GLU A 1 168 ? 146.039 162.643 91.924  1.00 232.53 ? 168  GLU A CB  1 
ATOM   823  N  N   . ASN A 1 169 ? 146.091 159.999 93.806  1.00 232.01 ? 169  ASN A N   1 
ATOM   824  C  CA  . ASN A 1 169 ? 146.641 159.260 94.939  1.00 232.01 ? 169  ASN A CA  1 
ATOM   825  C  C   . ASN A 1 169 ? 147.688 160.080 95.682  1.00 232.01 ? 169  ASN A C   1 
ATOM   826  O  O   . ASN A 1 169 ? 147.739 161.307 95.546  1.00 232.01 ? 169  ASN A O   1 
ATOM   827  C  CB  . ASN A 1 169 ? 147.235 157.925 94.480  1.00 232.01 ? 169  ASN A CB  1 
ATOM   828  N  N   . GLY A 1 170 ? 148.518 159.415 96.471  1.00 231.51 ? 170  GLY A N   1 
ATOM   829  C  CA  . GLY A 1 170 ? 149.545 160.101 97.240  1.00 231.51 ? 170  GLY A CA  1 
ATOM   830  C  C   . GLY A 1 170 ? 149.955 159.267 98.443  1.00 231.51 ? 170  GLY A C   1 
ATOM   831  O  O   . GLY A 1 170 ? 149.899 158.038 98.409  1.00 231.51 ? 170  GLY A O   1 
ATOM   832  N  N   . TRP A 1 171 ? 150.368 159.968 99.496  1.00 229.64 ? 171  TRP A N   1 
ATOM   833  C  CA  . TRP A 1 171 ? 150.773 159.333 100.743 1.00 229.64 ? 171  TRP A CA  1 
ATOM   834  C  C   . TRP A 1 171 ? 149.999 159.959 101.890 1.00 229.64 ? 171  TRP A C   1 
ATOM   835  O  O   . TRP A 1 171 ? 149.974 161.186 102.029 1.00 229.64 ? 171  TRP A O   1 
ATOM   836  C  CB  . TRP A 1 171 ? 152.282 159.477 100.977 1.00 229.64 ? 171  TRP A CB  1 
ATOM   837  N  N   . LEU A 1 172 ? 149.372 159.119 102.706 1.00 226.82 ? 172  LEU A N   1 
ATOM   838  C  CA  . LEU A 1 172 ? 148.577 159.566 103.838 1.00 226.82 ? 172  LEU A CA  1 
ATOM   839  C  C   . LEU A 1 172 ? 149.036 158.874 105.115 1.00 226.82 ? 172  LEU A C   1 
ATOM   840  O  O   . LEU A 1 172 ? 149.537 157.746 105.095 1.00 226.82 ? 172  LEU A O   1 
ATOM   841  C  CB  . LEU A 1 172 ? 147.087 159.296 103.602 1.00 226.82 ? 172  LEU A CB  1 
ATOM   842  N  N   . GLU A 1 173 ? 148.854 159.568 106.235 1.00 221.16 ? 173  GLU A N   1 
ATOM   843  C  CA  . GLU A 1 173 ? 149.193 159.057 107.561 1.00 221.16 ? 173  GLU A CA  1 
ATOM   844  C  C   . GLU A 1 173 ? 147.881 158.803 108.296 1.00 221.16 ? 173  GLU A C   1 
ATOM   845  O  O   . GLU A 1 173 ? 147.360 159.682 108.986 1.00 221.16 ? 173  GLU A O   1 
ATOM   846  C  CB  . GLU A 1 173 ? 150.090 160.035 108.320 1.00 221.16 ? 173  GLU A CB  1 
ATOM   847  N  N   . ILE A 1 174 ? 147.350 157.594 108.145 1.00 217.27 ? 174  ILE A N   1 
ATOM   848  C  CA  . ILE A 1 174 ? 146.064 157.232 108.736 1.00 217.27 ? 174  ILE A CA  1 
ATOM   849  C  C   . ILE A 1 174 ? 146.303 156.315 109.929 1.00 217.27 ? 174  ILE A C   1 
ATOM   850  O  O   . ILE A 1 174 ? 147.315 155.599 109.967 1.00 217.27 ? 174  ILE A O   1 
ATOM   851  C  CB  . ILE A 1 174 ? 145.145 156.566 107.700 1.00 217.27 ? 174  ILE A CB  1 
ATOM   852  N  N   . PRO A 1 175 ? 145.414 156.309 110.923 1.00 215.97 ? 175  PRO A N   1 
ATOM   853  C  CA  . PRO A 1 175 ? 145.582 155.390 112.055 1.00 215.97 ? 175  PRO A CA  1 
ATOM   854  C  C   . PRO A 1 175 ? 145.513 153.939 111.606 1.00 215.97 ? 175  PRO A C   1 
ATOM   855  O  O   . PRO A 1 175 ? 144.871 153.601 110.609 1.00 215.97 ? 175  PRO A O   1 
ATOM   856  C  CB  . PRO A 1 175 ? 144.412 155.743 112.981 1.00 215.97 ? 175  PRO A CB  1 
ATOM   857  C  CG  . PRO A 1 175 ? 144.019 157.127 112.605 1.00 215.97 ? 175  PRO A CG  1 
ATOM   858  C  CD  . PRO A 1 175 ? 144.341 157.293 111.150 1.00 215.97 ? 175  PRO A CD  1 
ATOM   859  N  N   . ILE A 1 176 ? 146.200 153.076 112.360 1.00 214.31 ? 176  ILE A N   1 
ATOM   860  C  CA  . ILE A 1 176 ? 146.241 151.654 112.028 1.00 214.31 ? 176  ILE A CA  1 
ATOM   861  C  C   . ILE A 1 176 ? 144.851 151.036 112.091 1.00 214.31 ? 176  ILE A C   1 
ATOM   862  O  O   . ILE A 1 176 ? 144.577 150.036 111.416 1.00 214.31 ? 176  ILE A O   1 
ATOM   863  C  CB  . ILE A 1 176 ? 147.224 150.919 112.959 1.00 214.31 ? 176  ILE A CB  1 
ATOM   864  N  N   . ASP A 1 177 ? 143.955 151.608 112.900 1.00 211.96 ? 177  ASP A N   1 
ATOM   865  C  CA  . ASP A 1 177 ? 142.593 151.091 112.979 1.00 211.96 ? 177  ASP A CA  1 
ATOM   866  C  C   . ASP A 1 177 ? 141.848 151.257 111.661 1.00 211.96 ? 177  ASP A C   1 
ATOM   867  O  O   . ASP A 1 177 ? 140.936 150.478 111.363 1.00 211.96 ? 177  ASP A O   1 
ATOM   868  C  CB  . ASP A 1 177 ? 141.832 151.784 114.109 1.00 211.96 ? 177  ASP A CB  1 
ATOM   869  N  N   . GLN A 1 178 ? 142.218 152.260 110.862 1.00 213.14 ? 178  GLN A N   1 
ATOM   870  C  CA  . GLN A 1 178 ? 141.575 152.479 109.573 1.00 213.14 ? 178  GLN A CA  1 
ATOM   871  C  C   . GLN A 1 178 ? 142.122 151.573 108.479 1.00 213.14 ? 178  GLN A C   1 
ATOM   872  O  O   . GLN A 1 178 ? 141.586 151.584 107.365 1.00 213.14 ? 178  GLN A O   1 
ATOM   873  C  CB  . GLN A 1 178 ? 141.726 153.942 109.153 1.00 213.14 ? 178  GLN A CB  1 
ATOM   874  N  N   . LEU A 1 179 ? 143.167 150.798 108.762 1.00 214.32 ? 179  LEU A N   1 
ATOM   875  C  CA  . LEU A 1 179 ? 143.762 149.917 107.763 1.00 214.32 ? 179  LEU A CA  1 
ATOM   876  C  C   . LEU A 1 179 ? 142.811 148.762 107.471 1.00 214.32 ? 179  LEU A C   1 
ATOM   877  O  O   . LEU A 1 179 ? 142.588 147.898 108.325 1.00 214.32 ? 179  LEU A O   1 
ATOM   878  C  CB  . LEU A 1 179 ? 145.113 149.403 108.251 1.00 214.32 ? 179  LEU A CB  1 
ATOM   879  N  N   . VAL A 1 180 ? 142.251 148.748 106.266 1.00 215.80 ? 180  VAL A N   1 
ATOM   880  C  CA  . VAL A 1 180 ? 141.335 147.693 105.839 1.00 215.80 ? 180  VAL A CA  1 
ATOM   881  C  C   . VAL A 1 180 ? 142.135 146.622 105.106 1.00 215.80 ? 180  VAL A C   1 
ATOM   882  O  O   . VAL A 1 180 ? 143.229 146.912 104.598 1.00 215.80 ? 180  VAL A O   1 
ATOM   883  C  CB  . VAL A 1 180 ? 140.212 148.257 104.954 1.00 215.80 ? 180  VAL A CB  1 
ATOM   884  N  N   . PRO A 1 181 ? 141.650 145.382 105.037 1.00 215.38 ? 181  PRO A N   1 
ATOM   885  C  CA  . PRO A 1 181 ? 142.372 144.353 104.280 1.00 215.38 ? 181  PRO A CA  1 
ATOM   886  C  C   . PRO A 1 181 ? 142.468 144.714 102.805 1.00 215.38 ? 181  PRO A C   1 
ATOM   887  O  O   . PRO A 1 181 ? 141.603 145.395 102.249 1.00 215.38 ? 181  PRO A O   1 
ATOM   888  C  CB  . PRO A 1 181 ? 141.525 143.094 104.495 1.00 215.38 ? 181  PRO A CB  1 
ATOM   889  C  CG  . PRO A 1 181 ? 140.802 143.345 105.775 1.00 215.38 ? 181  PRO A CG  1 
ATOM   890  C  CD  . PRO A 1 181 ? 140.511 144.818 105.782 1.00 215.38 ? 181  PRO A CD  1 
ATOM   891  N  N   . GLY A 1 182 ? 143.537 144.243 102.172 1.00 217.91 ? 182  GLY A N   1 
ATOM   892  C  CA  . GLY A 1 182 ? 143.799 144.586 100.785 1.00 217.91 ? 182  GLY A CA  1 
ATOM   893  C  C   . GLY A 1 182 ? 144.174 146.036 100.568 1.00 217.91 ? 182  GLY A C   1 
ATOM   894  O  O   . GLY A 1 182 ? 143.729 146.647 99.588  1.00 217.91 ? 182  GLY A O   1 
ATOM   895  N  N   . ASP A 1 183 ? 144.978 146.604 101.461 1.00 218.99 ? 183  ASP A N   1 
ATOM   896  C  CA  . ASP A 1 183 ? 145.452 147.975 101.342 1.00 218.99 ? 183  ASP A CA  1 
ATOM   897  C  C   . ASP A 1 183 ? 146.960 147.981 101.131 1.00 218.99 ? 183  ASP A C   1 
ATOM   898  O  O   . ASP A 1 183 ? 147.696 147.275 101.827 1.00 218.99 ? 183  ASP A O   1 
ATOM   899  C  CB  . ASP A 1 183 ? 145.094 148.792 102.587 1.00 218.99 ? 183  ASP A CB  1 
ATOM   900  N  N   . ILE A 1 184 ? 147.413 148.782 100.172 1.00 220.61 ? 184  ILE A N   1 
ATOM   901  C  CA  . ILE A 1 184 ? 148.828 148.890 99.834  1.00 220.61 ? 184  ILE A CA  1 
ATOM   902  C  C   . ILE A 1 184 ? 149.464 149.906 100.772 1.00 220.61 ? 184  ILE A C   1 
ATOM   903  O  O   . ILE A 1 184 ? 149.014 151.056 100.853 1.00 220.61 ? 184  ILE A O   1 
ATOM   904  C  CB  . ILE A 1 184 ? 149.026 149.293 98.365  1.00 220.61 ? 184  ILE A CB  1 
ATOM   905  N  N   . ILE A 1 185 ? 150.511 149.484 101.480 1.00 221.46 ? 185  ILE A N   1 
ATOM   906  C  CA  . ILE A 1 185 ? 151.197 150.330 102.446 1.00 221.46 ? 185  ILE A CA  1 
ATOM   907  C  C   . ILE A 1 185 ? 152.695 150.266 102.188 1.00 221.46 ? 185  ILE A C   1 
ATOM   908  O  O   . ILE A 1 185 ? 153.210 149.317 101.593 1.00 221.46 ? 185  ILE A O   1 
ATOM   909  C  CB  . ILE A 1 185 ? 150.884 149.925 103.902 1.00 221.46 ? 185  ILE A CB  1 
ATOM   910  N  N   . LYS A 1 186 ? 153.395 151.298 102.651 1.00 223.55 ? 186  LYS A N   1 
ATOM   911  C  CA  . LYS A 1 186 ? 154.841 151.398 102.523 1.00 223.55 ? 186  LYS A CA  1 
ATOM   912  C  C   . LYS A 1 186 ? 155.477 151.337 103.904 1.00 223.55 ? 186  LYS A C   1 
ATOM   913  O  O   . LYS A 1 186 ? 154.997 151.972 104.848 1.00 223.55 ? 186  LYS A O   1 
ATOM   914  C  CB  . LYS A 1 186 ? 155.248 152.695 101.814 1.00 223.55 ? 186  LYS A CB  1 
ATOM   915  N  N   . LEU A 1 187 ? 156.559 150.572 104.015 1.00 223.92 ? 187  LEU A N   1 
ATOM   916  C  CA  . LEU A 1 187 ? 157.248 150.366 105.279 1.00 223.92 ? 187  LEU A CA  1 
ATOM   917  C  C   . LEU A 1 187 ? 158.621 151.024 105.246 1.00 223.92 ? 187  LEU A C   1 
ATOM   918  O  O   . LEU A 1 187 ? 159.297 151.043 104.214 1.00 223.92 ? 187  LEU A O   1 
ATOM   919  C  CB  . LEU A 1 187 ? 157.396 148.873 105.588 1.00 223.92 ? 187  LEU A CB  1 
ATOM   920  N  N   . ALA A 1 188 ? 159.024 151.569 106.393 1.00 223.25 ? 188  ALA A N   1 
ATOM   921  C  CA  . ALA A 1 188 ? 160.316 152.220 106.543 1.00 223.25 ? 188  ALA A CA  1 
ATOM   922  C  C   . ALA A 1 188 ? 160.930 151.783 107.866 1.00 223.25 ? 188  ALA A C   1 
ATOM   923  O  O   . ALA A 1 188 ? 160.290 151.112 108.681 1.00 223.25 ? 188  ALA A O   1 
ATOM   924  C  CB  . ALA A 1 188 ? 160.183 153.746 106.465 1.00 223.25 ? 188  ALA A CB  1 
ATOM   925  N  N   . ALA A 1 189 ? 162.187 152.167 108.077 1.00 223.40 ? 189  ALA A N   1 
ATOM   926  C  CA  . ALA A 1 189 ? 162.885 151.799 109.301 1.00 223.40 ? 189  ALA A CA  1 
ATOM   927  C  C   . ALA A 1 189 ? 162.240 152.465 110.510 1.00 223.40 ? 189  ALA A C   1 
ATOM   928  O  O   . ALA A 1 189 ? 161.858 153.638 110.465 1.00 223.40 ? 189  ALA A O   1 
ATOM   929  C  CB  . ALA A 1 189 ? 164.360 152.189 109.208 1.00 223.40 ? 189  ALA A CB  1 
ATOM   930  N  N   . GLY A 1 190 ? 162.120 151.706 111.597 1.00 222.55 ? 190  GLY A N   1 
ATOM   931  C  CA  . GLY A 1 190 ? 161.554 152.212 112.828 1.00 222.55 ? 190  GLY A CA  1 
ATOM   932  C  C   . GLY A 1 190 ? 160.043 152.246 112.884 1.00 222.55 ? 190  GLY A C   1 
ATOM   933  O  O   . GLY A 1 190 ? 159.490 152.746 113.872 1.00 222.55 ? 190  GLY A O   1 
ATOM   934  N  N   . ASP A 1 191 ? 159.356 151.734 111.866 1.00 220.48 ? 191  ASP A N   1 
ATOM   935  C  CA  . ASP A 1 191 ? 157.900 151.733 111.821 1.00 220.48 ? 191  ASP A CA  1 
ATOM   936  C  C   . ASP A 1 191 ? 157.389 150.333 112.136 1.00 220.48 ? 191  ASP A C   1 
ATOM   937  O  O   . ASP A 1 191 ? 157.731 149.371 111.439 1.00 220.48 ? 191  ASP A O   1 
ATOM   938  C  CB  . ASP A 1 191 ? 157.397 152.194 110.453 1.00 220.48 ? 191  ASP A CB  1 
ATOM   939  N  N   . MET A 1 192 ? 156.576 150.222 113.183 1.00 219.06 ? 192  MET A N   1 
ATOM   940  C  CA  . MET A 1 192 ? 156.006 148.937 113.556 1.00 219.06 ? 192  MET A CA  1 
ATOM   941  C  C   . MET A 1 192 ? 154.944 148.506 112.550 1.00 219.06 ? 192  MET A C   1 
ATOM   942  O  O   . MET A 1 192 ? 154.251 149.331 111.949 1.00 219.06 ? 192  MET A O   1 
ATOM   943  C  CB  . MET A 1 192 ? 155.402 149.008 114.959 1.00 219.06 ? 192  MET A CB  1 
ATOM   944  N  N   . ILE A 1 193 ? 154.823 147.194 112.368 1.00 217.89 ? 193  ILE A N   1 
ATOM   945  C  CA  . ILE A 1 193 ? 153.837 146.628 111.451 1.00 217.89 ? 193  ILE A CA  1 
ATOM   946  C  C   . ILE A 1 193 ? 152.448 146.819 112.046 1.00 217.89 ? 193  ILE A C   1 
ATOM   947  O  O   . ILE A 1 193 ? 152.195 146.386 113.180 1.00 217.89 ? 193  ILE A O   1 
ATOM   948  C  CB  . ILE A 1 193 ? 154.122 145.146 111.166 1.00 217.89 ? 193  ILE A CB  1 
ATOM   949  N  N   . PRO A 1 194 ? 151.520 147.453 111.329 1.00 219.27 ? 194  PRO A N   1 
ATOM   950  C  CA  . PRO A 1 194 ? 150.187 147.693 111.896 1.00 219.27 ? 194  PRO A CA  1 
ATOM   951  C  C   . PRO A 1 194 ? 149.259 146.497 111.753 1.00 219.27 ? 194  PRO A C   1 
ATOM   952  O  O   . PRO A 1 194 ? 148.334 146.325 112.553 1.00 219.27 ? 194  PRO A O   1 
ATOM   953  C  CB  . PRO A 1 194 ? 149.673 148.900 111.095 1.00 219.27 ? 194  PRO A CB  1 
ATOM   954  C  CG  . PRO A 1 194 ? 150.676 149.129 109.971 1.00 219.27 ? 194  PRO A CG  1 
ATOM   955  C  CD  . PRO A 1 194 ? 151.646 147.991 109.967 1.00 219.27 ? 194  PRO A CD  1 
ATOM   956  N  N   . ALA A 1 195 ? 149.498 145.665 110.743 1.00 219.33 ? 195  ALA A N   1 
ATOM   957  C  CA  . ALA A 1 195 ? 148.657 144.503 110.490 1.00 219.33 ? 195  ALA A CA  1 
ATOM   958  C  C   . ALA A 1 195 ? 149.436 143.521 109.628 1.00 219.33 ? 195  ALA A C   1 
ATOM   959  O  O   . ALA A 1 195 ? 150.523 143.826 109.131 1.00 219.33 ? 195  ALA A O   1 
ATOM   960  C  CB  . ALA A 1 195 ? 147.339 144.899 109.818 1.00 219.33 ? 195  ALA A CB  1 
ATOM   961  N  N   . ASP A 1 196 ? 148.868 142.327 109.468 1.00 219.51 ? 196  ASP A N   1 
ATOM   962  C  CA  . ASP A 1 196 ? 149.475 141.320 108.609 1.00 219.51 ? 196  ASP A CA  1 
ATOM   963  C  C   . ASP A 1 196 ? 149.548 141.828 107.176 1.00 219.51 ? 196  ASP A C   1 
ATOM   964  O  O   . ASP A 1 196 ? 148.562 142.335 106.632 1.00 219.51 ? 196  ASP A O   1 
ATOM   965  C  CB  . ASP A 1 196 ? 148.676 140.018 108.673 1.00 219.51 ? 196  ASP A CB  1 
ATOM   966  N  N   . LEU A 1 197 ? 150.721 141.692 106.563 1.00 220.62 ? 197  LEU A N   1 
ATOM   967  C  CA  . LEU A 1 197 ? 150.964 142.217 105.229 1.00 220.62 ? 197  LEU A CA  1 
ATOM   968  C  C   . LEU A 1 197 ? 151.741 141.207 104.399 1.00 220.62 ? 197  LEU A C   1 
ATOM   969  O  O   . LEU A 1 197 ? 152.480 140.374 104.931 1.00 220.62 ? 197  LEU A O   1 
ATOM   970  C  CB  . LEU A 1 197 ? 151.731 143.546 105.283 1.00 220.62 ? 197  LEU A CB  1 
ATOM   971  N  N   . ARG A 1 198 ? 151.564 141.293 103.083 1.00 220.70 ? 198  ARG A N   1 
ATOM   972  C  CA  . ARG A 1 198 ? 152.293 140.474 102.123 1.00 220.70 ? 198  ARG A CA  1 
ATOM   973  C  C   . ARG A 1 198 ? 153.249 141.376 101.356 1.00 220.70 ? 198  ARG A C   1 
ATOM   974  O  O   . ARG A 1 198 ? 152.826 142.381 100.774 1.00 220.70 ? 198  ARG A O   1 
ATOM   975  C  CB  . ARG A 1 198 ? 151.335 139.761 101.168 1.00 220.70 ? 198  ARG A CB  1 
ATOM   976  N  N   . ILE A 1 199 ? 154.528 141.014 101.349 1.00 222.21 ? 199  ILE A N   1 
ATOM   977  C  CA  . ILE A 1 199 ? 155.563 141.863 100.769 1.00 222.21 ? 199  ILE A CA  1 
ATOM   978  C  C   . ILE A 1 199 ? 155.434 141.844 99.252  1.00 222.21 ? 199  ILE A C   1 
ATOM   979  O  O   . ILE A 1 199 ? 155.628 140.805 98.613  1.00 222.21 ? 199  ILE A O   1 
ATOM   980  C  CB  . ILE A 1 199 ? 156.961 141.407 101.209 1.00 222.21 ? 199  ILE A CB  1 
ATOM   981  N  N   . LEU A 1 200 ? 155.104 143.000 98.672  1.00 221.45 ? 200  LEU A N   1 
ATOM   982  C  CA  . LEU A 1 200 ? 155.067 143.126 97.219  1.00 221.45 ? 200  LEU A CA  1 
ATOM   983  C  C   . LEU A 1 200 ? 156.413 143.593 96.678  1.00 221.45 ? 200  LEU A C   1 
ATOM   984  O  O   . LEU A 1 200 ? 156.884 143.099 95.649  1.00 221.45 ? 200  LEU A O   1 
ATOM   985  C  CB  . LEU A 1 200 ? 153.954 144.089 96.803  1.00 221.45 ? 200  LEU A CB  1 
ATOM   986  N  N   . GLN A 1 201 ? 157.039 144.549 97.360  1.00 221.95 ? 201  GLN A N   1 
ATOM   987  C  CA  . GLN A 1 201 ? 158.368 145.026 97.010  1.00 221.95 ? 201  GLN A CA  1 
ATOM   988  C  C   . GLN A 1 201 ? 159.123 145.356 98.289  1.00 221.95 ? 201  GLN A C   1 
ATOM   989  O  O   . GLN A 1 201 ? 158.568 145.944 99.220  1.00 221.95 ? 201  GLN A O   1 
ATOM   990  C  CB  . GLN A 1 201 ? 158.308 146.258 96.097  1.00 221.95 ? 201  GLN A CB  1 
ATOM   991  N  N   . ALA A 1 202 ? 160.396 144.970 98.326  1.00 221.54 ? 202  ALA A N   1 
ATOM   992  C  CA  . ALA A 1 202 ? 161.222 145.185 99.505  1.00 221.54 ? 202  ALA A CA  1 
ATOM   993  C  C   . ALA A 1 202 ? 162.665 145.403 99.078  1.00 221.54 ? 202  ALA A C   1 
ATOM   994  O  O   . ALA A 1 202 ? 163.157 144.736 98.164  1.00 221.54 ? 202  ALA A O   1 
ATOM   995  C  CB  . ALA A 1 202 ? 161.131 144.002 100.476 1.00 221.54 ? 202  ALA A CB  1 
ATOM   996  N  N   . ARG A 1 203 ? 163.334 146.341 99.744  1.00 223.63 ? 203  ARG A N   1 
ATOM   997  C  CA  . ARG A 1 203 ? 164.735 146.664 99.480  1.00 223.63 ? 203  ARG A CA  1 
ATOM   998  C  C   . ARG A 1 203 ? 165.499 146.578 100.798 1.00 223.63 ? 203  ARG A C   1 
ATOM   999  O  O   . ARG A 1 203 ? 165.508 147.535 101.579 1.00 223.63 ? 203  ARG A O   1 
ATOM   1000 C  CB  . ARG A 1 203 ? 164.868 148.046 98.847  1.00 223.63 ? 203  ARG A CB  1 
ATOM   1001 N  N   . ASP A 1 204 ? 166.139 145.432 101.035 1.00 224.03 ? 204  ASP A N   1 
ATOM   1002 C  CA  . ASP A 1 204 ? 166.925 145.190 102.246 1.00 224.03 ? 204  ASP A CA  1 
ATOM   1003 C  C   . ASP A 1 204 ? 166.092 145.431 103.503 1.00 224.03 ? 204  ASP A C   1 
ATOM   1004 O  O   . ASP A 1 204 ? 166.535 146.060 104.467 1.00 224.03 ? 204  ASP A O   1 
ATOM   1005 C  CB  . ASP A 1 204 ? 168.194 146.045 102.254 1.00 224.03 ? 204  ASP A CB  1 
ATOM   1006 N  N   . LEU A 1 205 ? 164.864 144.919 103.486 1.00 223.22 ? 205  LEU A N   1 
ATOM   1007 C  CA  . LEU A 1 205 ? 163.954 145.090 104.609 1.00 223.22 ? 205  LEU A CA  1 
ATOM   1008 C  C   . LEU A 1 205 ? 164.245 144.053 105.686 1.00 223.22 ? 205  LEU A C   1 
ATOM   1009 O  O   . LEU A 1 205 ? 164.300 142.851 105.406 1.00 223.22 ? 205  LEU A O   1 
ATOM   1010 C  CB  . LEU A 1 205 ? 162.503 144.976 104.142 1.00 223.22 ? 205  LEU A CB  1 
ATOM   1011 N  N   . PHE A 1 206 ? 164.432 144.521 106.918 1.00 220.84 ? 206  PHE A N   1 
ATOM   1012 C  CA  . PHE A 1 206 ? 164.694 143.656 108.059 1.00 220.84 ? 206  PHE A CA  1 
ATOM   1013 C  C   . PHE A 1 206 ? 163.659 143.921 109.141 1.00 220.84 ? 206  PHE A C   1 
ATOM   1014 O  O   . PHE A 1 206 ? 163.360 145.077 109.457 1.00 220.84 ? 206  PHE A O   1 
ATOM   1015 C  CB  . PHE A 1 206 ? 166.106 143.878 108.617 1.00 220.84 ? 206  PHE A CB  1 
ATOM   1016 N  N   . VAL A 1 207 ? 163.114 142.847 109.705 1.00 217.93 ? 207  VAL A N   1 
ATOM   1017 C  CA  . VAL A 1 207 ? 162.085 142.929 110.733 1.00 217.93 ? 207  VAL A CA  1 
ATOM   1018 C  C   . VAL A 1 207 ? 162.529 142.114 111.939 1.00 217.93 ? 207  VAL A C   1 
ATOM   1019 O  O   . VAL A 1 207 ? 162.994 140.978 111.796 1.00 217.93 ? 207  VAL A O   1 
ATOM   1020 C  CB  . VAL A 1 207 ? 160.719 142.431 110.216 1.00 217.93 ? 207  VAL A CB  1 
ATOM   1021 N  N   . ALA A 1 208 ? 162.386 142.697 113.127 1.00 215.01 ? 208  ALA A N   1 
ATOM   1022 C  CA  . ALA A 1 208 ? 162.739 142.027 114.377 1.00 215.01 ? 208  ALA A CA  1 
ATOM   1023 C  C   . ALA A 1 208 ? 161.522 141.246 114.856 1.00 215.01 ? 208  ALA A C   1 
ATOM   1024 O  O   . ALA A 1 208 ? 160.552 141.824 115.352 1.00 215.01 ? 208  ALA A O   1 
ATOM   1025 C  CB  . ALA A 1 208 ? 163.206 143.037 115.419 1.00 215.01 ? 208  ALA A CB  1 
ATOM   1026 N  N   . GLN A 1 209 ? 161.574 139.922 114.708 1.00 212.90 ? 209  GLN A N   1 
ATOM   1027 C  CA  . GLN A 1 209 ? 160.476 139.038 115.082 1.00 212.90 ? 209  GLN A CA  1 
ATOM   1028 C  C   . GLN A 1 209 ? 160.709 138.362 116.429 1.00 212.90 ? 209  GLN A C   1 
ATOM   1029 O  O   . GLN A 1 209 ? 160.334 137.199 116.614 1.00 212.90 ? 209  GLN A O   1 
ATOM   1030 C  CB  . GLN A 1 209 ? 160.248 137.989 113.994 1.00 212.90 ? 209  GLN A CB  1 
ATOM   1031 N  N   . ALA A 1 210 ? 161.331 139.070 117.376 1.00 212.66 ? 210  ALA A N   1 
ATOM   1032 C  CA  . ALA A 1 210 ? 161.612 138.480 118.681 1.00 212.66 ? 210  ALA A CA  1 
ATOM   1033 C  C   . ALA A 1 210 ? 160.335 138.166 119.449 1.00 212.66 ? 210  ALA A C   1 
ATOM   1034 O  O   . ALA A 1 210 ? 160.305 137.214 120.237 1.00 212.66 ? 210  ALA A O   1 
ATOM   1035 C  CB  . ALA A 1 210 ? 162.506 139.414 119.497 1.00 212.66 ? 210  ALA A CB  1 
ATOM   1036 N  N   . SER A 1 211 ? 159.277 138.954 119.245 1.00 212.24 ? 211  SER A N   1 
ATOM   1037 C  CA  . SER A 1 211 ? 158.031 138.710 119.964 1.00 212.24 ? 211  SER A CA  1 
ATOM   1038 C  C   . SER A 1 211 ? 157.353 137.430 119.488 1.00 212.24 ? 211  SER A C   1 
ATOM   1039 O  O   . SER A 1 211 ? 156.900 136.620 120.306 1.00 212.24 ? 211  SER A O   1 
ATOM   1040 C  CB  . SER A 1 211 ? 157.092 139.906 119.804 1.00 212.24 ? 211  SER A CB  1 
ATOM   1041 N  N   . LEU A 1 212 ? 157.272 137.228 118.172 1.00 210.03 ? 212  LEU A N   1 
ATOM   1042 C  CA  . LEU A 1 212 ? 156.556 136.076 117.634 1.00 210.03 ? 212  LEU A CA  1 
ATOM   1043 C  C   . LEU A 1 212 ? 157.434 134.828 117.608 1.00 210.03 ? 212  LEU A C   1 
ATOM   1044 O  O   . LEU A 1 212 ? 157.125 133.824 118.259 1.00 210.03 ? 212  LEU A O   1 
ATOM   1045 C  CB  . LEU A 1 212 ? 156.033 136.394 116.231 1.00 210.03 ? 212  LEU A CB  1 
ATOM   1046 N  N   . THR A 1 213 ? 158.535 134.875 116.859 1.00 209.99 ? 213  THR A N   1 
ATOM   1047 C  CA  . THR A 1 213 ? 159.383 133.708 116.659 1.00 209.99 ? 213  THR A CA  1 
ATOM   1048 C  C   . THR A 1 213 ? 160.365 133.469 117.798 1.00 209.99 ? 213  THR A C   1 
ATOM   1049 O  O   . THR A 1 213 ? 160.958 132.387 117.865 1.00 209.99 ? 213  THR A O   1 
ATOM   1050 C  CB  . THR A 1 213 ? 160.162 133.839 115.345 1.00 209.99 ? 213  THR A CB  1 
ATOM   1051 N  N   . GLY A 1 214 ? 160.552 134.439 118.689 1.00 211.55 ? 214  GLY A N   1 
ATOM   1052 C  CA  . GLY A 1 214 ? 161.486 134.281 119.783 1.00 211.55 ? 214  GLY A CA  1 
ATOM   1053 C  C   . GLY A 1 214 ? 162.939 134.487 119.424 1.00 211.55 ? 214  GLY A C   1 
ATOM   1054 O  O   . GLY A 1 214 ? 163.807 134.254 120.273 1.00 211.55 ? 214  GLY A O   1 
ATOM   1055 N  N   . GLU A 1 215 ? 163.234 134.916 118.201 1.00 213.29 ? 215  GLU A N   1 
ATOM   1056 C  CA  . GLU A 1 215 ? 164.600 135.146 117.751 1.00 213.29 ? 215  GLU A CA  1 
ATOM   1057 C  C   . GLU A 1 215 ? 164.872 136.643 117.705 1.00 213.29 ? 215  GLU A C   1 
ATOM   1058 O  O   . GLU A 1 215 ? 164.164 137.386 117.017 1.00 213.29 ? 215  GLU A O   1 
ATOM   1059 C  CB  . GLU A 1 215 ? 164.836 134.521 116.374 1.00 213.29 ? 215  GLU A CB  1 
ATOM   1060 N  N   . SER A 1 216 ? 165.903 137.079 118.432 1.00 215.09 ? 216  SER A N   1 
ATOM   1061 C  CA  . SER A 1 216 ? 166.221 138.502 118.483 1.00 215.09 ? 216  SER A CA  1 
ATOM   1062 C  C   . SER A 1 216 ? 166.851 138.989 117.185 1.00 215.09 ? 216  SER A C   1 
ATOM   1063 O  O   . SER A 1 216 ? 166.708 140.166 116.833 1.00 215.09 ? 216  SER A O   1 
ATOM   1064 C  CB  . SER A 1 216 ? 167.148 138.791 119.664 1.00 215.09 ? 216  SER A CB  1 
ATOM   1065 N  N   . LEU A 1 217 ? 167.548 138.114 116.471 1.00 216.56 ? 217  LEU A N   1 
ATOM   1066 C  CA  . LEU A 1 217 ? 168.176 138.508 115.215 1.00 216.56 ? 217  LEU A CA  1 
ATOM   1067 C  C   . LEU A 1 217 ? 167.106 138.823 114.175 1.00 216.56 ? 217  LEU A C   1 
ATOM   1068 O  O   . LEU A 1 217 ? 166.180 138.025 113.986 1.00 216.56 ? 217  LEU A O   1 
ATOM   1069 C  CB  . LEU A 1 217 ? 169.097 137.402 114.708 1.00 216.56 ? 217  LEU A CB  1 
ATOM   1070 N  N   . PRO A 1 218 ? 167.187 139.964 113.495 1.00 216.74 ? 218  PRO A N   1 
ATOM   1071 C  CA  . PRO A 1 218 ? 166.180 140.288 112.479 1.00 216.74 ? 218  PRO A CA  1 
ATOM   1072 C  C   . PRO A 1 218 ? 166.240 139.325 111.304 1.00 216.74 ? 218  PRO A C   1 
ATOM   1073 O  O   . PRO A 1 218 ? 167.294 138.784 110.962 1.00 216.74 ? 218  PRO A O   1 
ATOM   1074 C  CB  . PRO A 1 218 ? 166.552 141.712 112.050 1.00 216.74 ? 218  PRO A CB  1 
ATOM   1075 C  CG  . PRO A 1 218 ? 167.997 141.845 112.390 1.00 216.74 ? 218  PRO A CG  1 
ATOM   1076 C  CD  . PRO A 1 218 ? 168.207 141.018 113.624 1.00 216.74 ? 218  PRO A CD  1 
ATOM   1077 N  N   . VAL A 1 219 ? 165.082 139.117 110.684 1.00 217.07 ? 219  VAL A N   1 
ATOM   1078 C  CA  . VAL A 1 219 ? 164.942 138.234 109.533 1.00 217.07 ? 219  VAL A CA  1 
ATOM   1079 C  C   . VAL A 1 219 ? 164.644 139.089 108.311 1.00 217.07 ? 219  VAL A C   1 
ATOM   1080 O  O   . VAL A 1 219 ? 163.708 139.897 108.326 1.00 217.07 ? 219  VAL A O   1 
ATOM   1081 C  CB  . VAL A 1 219 ? 163.837 137.184 109.750 1.00 217.07 ? 219  VAL A CB  1 
ATOM   1082 N  N   . GLU A 1 220 ? 165.441 138.915 107.260 1.00 218.87 ? 220  GLU A N   1 
ATOM   1083 C  CA  . GLU A 1 220 ? 165.251 139.685 106.040 1.00 218.87 ? 220  GLU A CA  1 
ATOM   1084 C  C   . GLU A 1 220 ? 163.943 139.299 105.360 1.00 218.87 ? 220  GLU A C   1 
ATOM   1085 O  O   . GLU A 1 220 ? 163.583 138.120 105.290 1.00 218.87 ? 220  GLU A O   1 
ATOM   1086 C  CB  . GLU A 1 220 ? 166.425 139.467 105.085 1.00 218.87 ? 220  GLU A CB  1 
ATOM   1087 N  N   . LYS A 1 221 ? 163.230 140.304 104.856 1.00 221.62 ? 221  LYS A N   1 
ATOM   1088 C  CA  . LYS A 1 221 ? 161.961 140.111 104.162 1.00 221.62 ? 221  LYS A CA  1 
ATOM   1089 C  C   . LYS A 1 221 ? 162.145 140.521 102.707 1.00 221.62 ? 221  LYS A C   1 
ATOM   1090 O  O   . LYS A 1 221 ? 162.552 141.653 102.423 1.00 221.62 ? 221  LYS A O   1 
ATOM   1091 C  CB  . LYS A 1 221 ? 160.844 140.916 104.824 1.00 221.62 ? 221  LYS A CB  1 
ATOM   1092 N  N   . ALA A 1 222 ? 161.845 139.607 101.792 1.00 221.53 ? 222  ALA A N   1 
ATOM   1093 C  CA  . ALA A 1 222 ? 161.986 139.847 100.365 1.00 221.53 ? 222  ALA A CA  1 
ATOM   1094 C  C   . ALA A 1 222 ? 160.619 139.965 99.701  1.00 221.53 ? 222  ALA A C   1 
ATOM   1095 O  O   . ALA A 1 222 ? 159.595 139.547 100.248 1.00 221.53 ? 222  ALA A O   1 
ATOM   1096 C  CB  . ALA A 1 222 ? 162.796 138.728 99.704  1.00 221.53 ? 222  ALA A CB  1 
ATOM   1097 N  N   . ALA A 1 223 ? 160.618 140.554 98.503  1.00 221.35 ? 223  ALA A N   1 
ATOM   1098 C  CA  . ALA A 1 223 ? 159.381 140.676 97.738  1.00 221.35 ? 223  ALA A CA  1 
ATOM   1099 C  C   . ALA A 1 223 ? 158.827 139.308 97.364  1.00 221.35 ? 223  ALA A C   1 
ATOM   1100 O  O   . ALA A 1 223 ? 157.612 139.083 97.424  1.00 221.35 ? 223  ALA A O   1 
ATOM   1101 C  CB  . ALA A 1 223 ? 159.619 141.521 96.487  1.00 221.35 ? 223  ALA A CB  1 
ATOM   1102 N  N   . THR A 1 224 ? 159.700 138.383 96.977  1.00 222.55 ? 224  THR A N   1 
ATOM   1103 C  CA  . THR A 1 224 ? 159.313 137.024 96.635  1.00 222.55 ? 224  THR A CA  1 
ATOM   1104 C  C   . THR A 1 224 ? 159.863 136.060 97.677  1.00 222.55 ? 224  THR A C   1 
ATOM   1105 O  O   . THR A 1 224 ? 160.927 136.292 98.260  1.00 222.55 ? 224  THR A O   1 
ATOM   1106 C  CB  . THR A 1 224 ? 159.820 136.628 95.242  1.00 222.55 ? 224  THR A CB  1 
ATOM   1107 N  N   . THR A 1 225 ? 159.125 134.978 97.911  1.00 223.42 ? 225  THR A N   1 
ATOM   1108 C  CA  . THR A 1 225 ? 159.509 133.993 98.917  1.00 223.42 ? 225  THR A CA  1 
ATOM   1109 C  C   . THR A 1 225 ? 160.760 133.253 98.457  1.00 223.42 ? 225  THR A C   1 
ATOM   1110 O  O   . THR A 1 225 ? 160.696 132.407 97.559  1.00 223.42 ? 225  THR A O   1 
ATOM   1111 C  CB  . THR A 1 225 ? 158.362 133.018 99.168  1.00 223.42 ? 225  THR A CB  1 
ATOM   1112 N  N   . ARG A 1 226 ? 161.900 133.570 99.070  1.00 222.67 ? 226  ARG A N   1 
ATOM   1113 C  CA  . ARG A 1 226 ? 163.160 132.912 98.758  1.00 222.67 ? 226  ARG A CA  1 
ATOM   1114 C  C   . ARG A 1 226 ? 163.420 131.680 99.614  1.00 222.67 ? 226  ARG A C   1 
ATOM   1115 O  O   . ARG A 1 226 ? 164.398 130.968 99.365  1.00 222.67 ? 226  ARG A O   1 
ATOM   1116 C  CB  . ARG A 1 226 ? 164.327 133.896 98.918  1.00 222.67 ? 226  ARG A CB  1 
ATOM   1117 N  N   . GLN A 1 227 ? 162.576 131.415 100.612 1.00 223.61 ? 227  GLN A N   1 
ATOM   1118 C  CA  . GLN A 1 227 ? 162.748 130.244 101.460 1.00 223.61 ? 227  GLN A CA  1 
ATOM   1119 C  C   . GLN A 1 227 ? 162.427 128.973 100.676 1.00 223.61 ? 227  GLN A C   1 
ATOM   1120 O  O   . GLN A 1 227 ? 161.450 128.936 99.923  1.00 223.61 ? 227  GLN A O   1 
ATOM   1121 C  CB  . GLN A 1 227 ? 161.850 130.335 102.692 1.00 223.61 ? 227  GLN A CB  1 
ATOM   1122 N  N   . PRO A 1 228 ? 163.231 127.920 100.832 1.00 223.60 ? 228  PRO A N   1 
ATOM   1123 C  CA  . PRO A 1 228 ? 162.975 126.680 100.085 1.00 223.60 ? 228  PRO A CA  1 
ATOM   1124 C  C   . PRO A 1 228 ? 161.804 125.886 100.641 1.00 223.60 ? 228  PRO A C   1 
ATOM   1125 O  O   . PRO A 1 228 ? 161.012 125.323 99.878  1.00 223.60 ? 228  PRO A O   1 
ATOM   1126 C  CB  . PRO A 1 228 ? 164.291 125.903 100.220 1.00 223.60 ? 228  PRO A CB  1 
ATOM   1127 C  CG  . PRO A 1 228 ? 164.997 126.490 101.396 1.00 223.60 ? 228  PRO A CG  1 
ATOM   1128 C  CD  . PRO A 1 228 ? 164.386 127.815 101.741 1.00 223.60 ? 228  PRO A CD  1 
ATOM   1129 N  N   . GLU A 1 229 ? 161.681 125.834 101.964 1.00 226.81 ? 229  GLU A N   1 
ATOM   1130 C  CA  . GLU A 1 229 ? 160.695 124.998 102.635 1.00 226.81 ? 229  GLU A CA  1 
ATOM   1131 C  C   . GLU A 1 229 ? 159.487 125.833 103.038 1.00 226.81 ? 229  GLU A C   1 
ATOM   1132 O  O   . GLU A 1 229 ? 159.636 126.897 103.648 1.00 226.81 ? 229  GLU A O   1 
ATOM   1133 C  CB  . GLU A 1 229 ? 161.302 124.322 103.867 1.00 226.81 ? 229  GLU A CB  1 
ATOM   1134 N  N   . HIS A 1 230 ? 158.299 125.345 102.695 1.00 230.67 ? 230  HIS A N   1 
ATOM   1135 C  CA  . HIS A 1 230 ? 157.043 125.984 103.060 1.00 230.67 ? 230  HIS A CA  1 
ATOM   1136 C  C   . HIS A 1 230 ? 156.549 125.391 104.383 1.00 230.67 ? 230  HIS A C   1 
ATOM   1137 O  O   . HIS A 1 230 ? 157.304 124.728 105.098 1.00 230.67 ? 230  HIS A O   1 
ATOM   1138 C  CB  . HIS A 1 230 ? 156.030 125.827 101.922 1.00 230.67 ? 230  HIS A CB  1 
ATOM   1139 N  N   . SER A 1 231 ? 155.286 125.651 104.730 1.00 233.01 ? 231  SER A N   1 
ATOM   1140 C  CA  . SER A 1 231 ? 154.581 125.141 105.912 1.00 233.01 ? 231  SER A CA  1 
ATOM   1141 C  C   . SER A 1 231 ? 155.057 125.801 107.199 1.00 233.01 ? 231  SER A C   1 
ATOM   1142 O  O   . SER A 1 231 ? 154.844 125.240 108.286 1.00 233.01 ? 231  SER A O   1 
ATOM   1143 C  CB  . SER A 1 231 ? 154.692 123.619 106.059 1.00 233.01 ? 231  SER A CB  1 
ATOM   1144 N  N   . ASN A 1 232 ? 155.694 126.965 107.119 1.00 233.66 ? 232  ASN A N   1 
ATOM   1145 C  CA  . ASN A 1 232 ? 156.099 127.729 108.300 1.00 233.66 ? 232  ASN A CA  1 
ATOM   1146 C  C   . ASN A 1 232 ? 155.565 129.148 108.166 1.00 233.66 ? 232  ASN A C   1 
ATOM   1147 O  O   . ASN A 1 232 ? 156.297 130.049 107.718 1.00 233.66 ? 232  ASN A O   1 
ATOM   1148 C  CB  . ASN A 1 232 ? 157.618 127.735 108.457 1.00 233.66 ? 232  ASN A CB  1 
ATOM   1149 N  N   . PRO A 1 233 ? 154.301 129.395 108.522 1.00 232.29 ? 233  PRO A N   1 
ATOM   1150 C  CA  . PRO A 1 233 ? 153.740 130.744 108.341 1.00 232.29 ? 233  PRO A CA  1 
ATOM   1151 C  C   . PRO A 1 233 ? 154.473 131.822 109.119 1.00 232.29 ? 233  PRO A C   1 
ATOM   1152 O  O   . PRO A 1 233 ? 154.603 132.948 108.624 1.00 232.29 ? 233  PRO A O   1 
ATOM   1153 C  CB  . PRO A 1 233 ? 152.291 130.586 108.821 1.00 232.29 ? 233  PRO A CB  1 
ATOM   1154 C  CG  . PRO A 1 233 ? 152.323 129.411 109.744 1.00 232.29 ? 233  PRO A CG  1 
ATOM   1155 C  CD  . PRO A 1 233 ? 153.350 128.479 109.173 1.00 232.29 ? 233  PRO A CD  1 
ATOM   1156 N  N   . LEU A 1 234 ? 154.967 131.512 110.320 1.00 233.30 ? 234  LEU A N   1 
ATOM   1157 C  CA  . LEU A 1 234 ? 155.668 132.519 111.108 1.00 233.30 ? 234  LEU A CA  1 
ATOM   1158 C  C   . LEU A 1 234 ? 157.058 132.801 110.554 1.00 233.30 ? 234  LEU A C   1 
ATOM   1159 O  O   . LEU A 1 234 ? 157.569 133.917 110.705 1.00 233.30 ? 234  LEU A O   1 
ATOM   1160 C  CB  . LEU A 1 234 ? 155.760 132.075 112.568 1.00 233.30 ? 234  LEU A CB  1 
ATOM   1161 N  N   . GLU A 1 235 ? 157.682 131.814 109.914 1.00 233.94 ? 235  GLU A N   1 
ATOM   1162 C  CA  . GLU A 1 235 ? 159.020 131.956 109.359 1.00 233.94 ? 235  GLU A CA  1 
ATOM   1163 C  C   . GLU A 1 235 ? 159.009 132.372 107.893 1.00 233.94 ? 235  GLU A C   1 
ATOM   1164 O  O   . GLU A 1 235 ? 160.076 132.443 107.274 1.00 233.94 ? 235  GLU A O   1 
ATOM   1165 C  CB  . GLU A 1 235 ? 159.801 130.651 109.527 1.00 233.94 ? 235  GLU A CB  1 
ATOM   1166 N  N   . CYS A 1 236 ? 157.836 132.641 107.325 1.00 230.16 ? 236  CYS A N   1 
ATOM   1167 C  CA  . CYS A 1 236 ? 157.757 133.040 105.927 1.00 230.16 ? 236  CYS A CA  1 
ATOM   1168 C  C   . CYS A 1 236 ? 158.373 134.421 105.737 1.00 230.16 ? 236  CYS A C   1 
ATOM   1169 O  O   . CYS A 1 236 ? 158.048 135.365 106.464 1.00 230.16 ? 236  CYS A O   1 
ATOM   1170 C  CB  . CYS A 1 236 ? 156.304 133.038 105.456 1.00 230.16 ? 236  CYS A CB  1 
ATOM   1171 N  N   . ASP A 1 237 ? 159.266 134.537 104.753 1.00 226.58 ? 237  ASP A N   1 
ATOM   1172 C  CA  . ASP A 1 237 ? 159.955 135.794 104.492 1.00 226.58 ? 237  ASP A CA  1 
ATOM   1173 C  C   . ASP A 1 237 ? 159.106 136.792 103.716 1.00 226.58 ? 237  ASP A C   1 
ATOM   1174 O  O   . ASP A 1 237 ? 159.431 137.984 103.713 1.00 226.58 ? 237  ASP A O   1 
ATOM   1175 C  CB  . ASP A 1 237 ? 161.257 135.530 103.730 1.00 226.58 ? 237  ASP A CB  1 
ATOM   1176 N  N   . THR A 1 238 ? 158.037 136.343 103.063 1.00 223.68 ? 238  THR A N   1 
ATOM   1177 C  CA  . THR A 1 238 ? 157.171 137.220 102.289 1.00 223.68 ? 238  THR A CA  1 
ATOM   1178 C  C   . THR A 1 238 ? 155.964 137.710 103.076 1.00 223.68 ? 238  THR A C   1 
ATOM   1179 O  O   . THR A 1 238 ? 155.131 138.433 102.521 1.00 223.68 ? 238  THR A O   1 
ATOM   1180 C  CB  . THR A 1 238 ? 156.697 136.509 101.016 1.00 223.68 ? 238  THR A CB  1 
ATOM   1181 N  N   . LEU A 1 239 ? 155.848 137.338 104.349 1.00 223.26 ? 239  LEU A N   1 
ATOM   1182 C  CA  . LEU A 1 239 ? 154.717 137.727 105.180 1.00 223.26 ? 239  LEU A CA  1 
ATOM   1183 C  C   . LEU A 1 239 ? 155.227 138.404 106.443 1.00 223.26 ? 239  LEU A C   1 
ATOM   1184 O  O   . LEU A 1 239 ? 156.122 137.881 107.114 1.00 223.26 ? 239  LEU A O   1 
ATOM   1185 C  CB  . LEU A 1 239 ? 153.852 136.515 105.541 1.00 223.26 ? 239  LEU A CB  1 
ATOM   1186 N  N   . CYS A 1 240 ? 154.657 139.563 106.760 1.00 222.44 ? 240  CYS A N   1 
ATOM   1187 C  CA  . CYS A 1 240 ? 154.977 140.303 107.973 1.00 222.44 ? 240  CYS A CA  1 
ATOM   1188 C  C   . CYS A 1 240 ? 153.726 140.407 108.834 1.00 222.44 ? 240  CYS A C   1 
ATOM   1189 O  O   . CYS A 1 240 ? 152.664 140.807 108.346 1.00 222.44 ? 240  CYS A O   1 
ATOM   1190 C  CB  . CYS A 1 240 ? 155.515 141.697 107.642 1.00 222.44 ? 240  CYS A CB  1 
ATOM   1191 N  N   . PHE A 1 241 ? 153.854 140.050 110.107 1.00 222.85 ? 241  PHE A N   1 
ATOM   1192 C  CA  . PHE A 1 241 ? 152.729 140.024 111.029 1.00 222.85 ? 241  PHE A CA  1 
ATOM   1193 C  C   . PHE A 1 241 ? 152.699 141.279 111.893 1.00 222.85 ? 241  PHE A C   1 
ATOM   1194 O  O   . PHE A 1 241 ? 153.703 141.976 112.060 1.00 222.85 ? 241  PHE A O   1 
ATOM   1195 C  CB  . PHE A 1 241 ? 152.787 138.778 111.918 1.00 222.85 ? 241  PHE A CB  1 
ATOM   1196 C  CG  . PHE A 1 241 ? 152.740 137.487 111.154 1.00 222.85 ? 241  PHE A CG  1 
ATOM   1197 C  CD1 . PHE A 1 241 ? 153.906 136.871 110.733 1.00 222.85 ? 241  PHE A CD1 1 
ATOM   1198 C  CD2 . PHE A 1 241 ? 151.527 136.890 110.855 1.00 222.85 ? 241  PHE A CD2 1 
ATOM   1199 C  CE1 . PHE A 1 241 ? 153.863 135.683 110.029 1.00 222.85 ? 241  PHE A CE1 1 
ATOM   1200 C  CE2 . PHE A 1 241 ? 151.477 135.702 110.153 1.00 222.85 ? 241  PHE A CE2 1 
ATOM   1201 C  CZ  . PHE A 1 241 ? 152.647 135.098 109.739 1.00 222.85 ? 241  PHE A CZ  1 
ATOM   1202 N  N   . MET A 1 242 ? 151.520 141.557 112.443 1.00 220.12 ? 242  MET A N   1 
ATOM   1203 C  CA  . MET A 1 242 ? 151.344 142.713 113.310 1.00 220.12 ? 242  MET A CA  1 
ATOM   1204 C  C   . MET A 1 242 ? 152.114 142.529 114.612 1.00 220.12 ? 242  MET A C   1 
ATOM   1205 O  O   . MET A 1 242 ? 152.347 141.404 115.064 1.00 220.12 ? 242  MET A O   1 
ATOM   1206 C  CB  . MET A 1 242 ? 149.861 142.936 113.605 1.00 220.12 ? 242  MET A CB  1 
ATOM   1207 N  N   . GLY A 1 243 ? 152.511 143.647 115.216 1.00 218.56 ? 243  GLY A N   1 
ATOM   1208 C  CA  . GLY A 1 243 ? 153.262 143.633 116.452 1.00 218.56 ? 243  GLY A CA  1 
ATOM   1209 C  C   . GLY A 1 243 ? 154.766 143.661 116.291 1.00 218.56 ? 243  GLY A C   1 
ATOM   1210 O  O   . GLY A 1 243 ? 155.476 143.752 117.300 1.00 218.56 ? 243  GLY A O   1 
ATOM   1211 N  N   . THR A 1 244 ? 155.272 143.587 115.065 1.00 218.75 ? 244  THR A N   1 
ATOM   1212 C  CA  . THR A 1 244 ? 156.700 143.621 114.796 1.00 218.75 ? 244  THR A CA  1 
ATOM   1213 C  C   . THR A 1 244 ? 157.085 144.960 114.181 1.00 218.75 ? 244  THR A C   1 
ATOM   1214 O  O   . THR A 1 244 ? 156.270 145.642 113.555 1.00 218.75 ? 244  THR A O   1 
ATOM   1215 C  CB  . THR A 1 244 ? 157.113 142.480 113.860 1.00 218.75 ? 244  THR A CB  1 
ATOM   1216 N  N   . THR A 1 245 ? 158.347 145.332 114.372 1.00 219.60 ? 245  THR A N   1 
ATOM   1217 C  CA  . THR A 1 245 ? 158.890 146.575 113.850 1.00 219.60 ? 245  THR A CA  1 
ATOM   1218 C  C   . THR A 1 245 ? 159.893 146.286 112.740 1.00 219.60 ? 245  THR A C   1 
ATOM   1219 O  O   . THR A 1 245 ? 160.390 145.166 112.595 1.00 219.60 ? 245  THR A O   1 
ATOM   1220 C  CB  . THR A 1 245 ? 159.561 147.394 114.958 1.00 219.60 ? 245  THR A CB  1 
ATOM   1221 N  N   . VAL A 1 246 ? 160.185 147.317 111.955 1.00 221.22 ? 246  VAL A N   1 
ATOM   1222 C  CA  . VAL A 1 246 ? 161.136 147.227 110.854 1.00 221.22 ? 246  VAL A CA  1 
ATOM   1223 C  C   . VAL A 1 246 ? 162.452 147.820 111.336 1.00 221.22 ? 246  VAL A C   1 
ATOM   1224 O  O   . VAL A 1 246 ? 162.533 149.015 111.639 1.00 221.22 ? 246  VAL A O   1 
ATOM   1225 C  CB  . VAL A 1 246 ? 160.622 147.948 109.601 1.00 221.22 ? 246  VAL A CB  1 
ATOM   1226 N  N   . VAL A 1 247 ? 163.488 146.982 111.410 1.00 221.53 ? 247  VAL A N   1 
ATOM   1227 C  CA  . VAL A 1 247 ? 164.780 147.437 111.915 1.00 221.53 ? 247  VAL A CA  1 
ATOM   1228 C  C   . VAL A 1 247 ? 165.418 148.423 110.944 1.00 221.53 ? 247  VAL A C   1 
ATOM   1229 O  O   . VAL A 1 247 ? 165.902 149.488 111.344 1.00 221.53 ? 247  VAL A O   1 
ATOM   1230 C  CB  . VAL A 1 247 ? 165.702 146.235 112.187 1.00 221.53 ? 247  VAL A CB  1 
ATOM   1231 N  N   . SER A 1 248 ? 165.424 148.088 109.657 1.00 224.09 ? 248  SER A N   1 
ATOM   1232 C  CA  . SER A 1 248 ? 166.051 148.934 108.651 1.00 224.09 ? 248  SER A CA  1 
ATOM   1233 C  C   . SER A 1 248 ? 165.469 148.590 107.288 1.00 224.09 ? 248  SER A C   1 
ATOM   1234 O  O   . SER A 1 248 ? 164.797 147.571 107.114 1.00 224.09 ? 248  SER A O   1 
ATOM   1235 C  CB  . SER A 1 248 ? 167.575 148.772 108.654 1.00 224.09 ? 248  SER A CB  1 
ATOM   1236 N  N   . GLY A 1 249 ? 165.739 149.461 106.319 1.00 225.37 ? 249  GLY A N   1 
ATOM   1237 C  CA  . GLY A 1 249 ? 165.296 149.262 104.958 1.00 225.37 ? 249  GLY A CA  1 
ATOM   1238 C  C   . GLY A 1 249 ? 163.901 149.805 104.702 1.00 225.37 ? 249  GLY A C   1 
ATOM   1239 O  O   . GLY A 1 249 ? 163.195 150.272 105.599 1.00 225.37 ? 249  GLY A O   1 
ATOM   1240 N  N   . THR A 1 250 ? 163.504 149.737 103.434 1.00 224.56 ? 250  THR A N   1 
ATOM   1241 C  CA  . THR A 1 250 ? 162.195 150.195 102.995 1.00 224.56 ? 250  THR A CA  1 
ATOM   1242 C  C   . THR A 1 250 ? 161.518 149.096 102.191 1.00 224.56 ? 250  THR A C   1 
ATOM   1243 O  O   . THR A 1 250 ? 162.180 148.284 101.538 1.00 224.56 ? 250  THR A O   1 
ATOM   1244 C  CB  . THR A 1 250 ? 162.294 151.472 102.148 1.00 224.56 ? 250  THR A CB  1 
ATOM   1245 N  N   . ALA A 1 251 ? 160.190 149.077 102.244 1.00 222.89 ? 251  ALA A N   1 
ATOM   1246 C  CA  . ALA A 1 251 ? 159.408 148.056 101.560 1.00 222.89 ? 251  ALA A CA  1 
ATOM   1247 C  C   . ALA A 1 251 ? 158.012 148.607 101.299 1.00 222.89 ? 251  ALA A C   1 
ATOM   1248 O  O   . ALA A 1 251 ? 157.602 149.618 101.876 1.00 222.89 ? 251  ALA A O   1 
ATOM   1249 C  CB  . ALA A 1 251 ? 159.358 146.760 102.375 1.00 222.89 ? 251  ALA A CB  1 
ATOM   1250 N  N   . GLN A 1 252 ? 157.282 147.926 100.419 1.00 221.20 ? 252  GLN A N   1 
ATOM   1251 C  CA  . GLN A 1 252 ? 155.909 148.306 100.092 1.00 221.20 ? 252  GLN A CA  1 
ATOM   1252 C  C   . GLN A 1 252 ? 155.081 147.031 100.039 1.00 221.20 ? 252  GLN A C   1 
ATOM   1253 O  O   . GLN A 1 252 ? 155.149 146.287 99.056  1.00 221.20 ? 252  GLN A O   1 
ATOM   1254 C  CB  . GLN A 1 252 ? 155.844 149.062 98.768  1.00 221.20 ? 252  GLN A CB  1 
ATOM   1255 N  N   . ALA A 1 253 ? 154.305 146.782 101.088 1.00 220.66 ? 253  ALA A N   1 
ATOM   1256 C  CA  . ALA A 1 253 ? 153.532 145.559 101.234 1.00 220.66 ? 253  ALA A CA  1 
ATOM   1257 C  C   . ALA A 1 253 ? 152.041 145.858 101.102 1.00 220.66 ? 253  ALA A C   1 
ATOM   1258 O  O   . ALA A 1 253 ? 151.615 147.012 101.000 1.00 220.66 ? 253  ALA A O   1 
ATOM   1259 C  CB  . ALA A 1 253 ? 153.842 144.889 102.574 1.00 220.66 ? 253  ALA A CB  1 
ATOM   1260 N  N   . MET A 1 254 ? 151.243 144.792 101.103 1.00 218.52 ? 254  MET A N   1 
ATOM   1261 C  CA  . MET A 1 254 ? 149.793 144.889 101.011 1.00 218.52 ? 254  MET A CA  1 
ATOM   1262 C  C   . MET A 1 254 ? 149.174 144.162 102.194 1.00 218.52 ? 254  MET A C   1 
ATOM   1263 O  O   . MET A 1 254 ? 149.535 143.016 102.479 1.00 218.52 ? 254  MET A O   1 
ATOM   1264 C  CB  . MET A 1 254 ? 149.278 144.298 99.694  1.00 218.52 ? 254  MET A CB  1 
ATOM   1265 N  N   . VAL A 1 255 ? 148.239 144.825 102.873 1.00 216.78 ? 255  VAL A N   1 
ATOM   1266 C  CA  . VAL A 1 255 ? 147.618 144.251 104.061 1.00 216.78 ? 255  VAL A CA  1 
ATOM   1267 C  C   . VAL A 1 255 ? 146.724 143.087 103.657 1.00 216.78 ? 255  VAL A C   1 
ATOM   1268 O  O   . VAL A 1 255 ? 145.961 143.174 102.687 1.00 216.78 ? 255  VAL A O   1 
ATOM   1269 C  CB  . VAL A 1 255 ? 146.827 145.321 104.826 1.00 216.78 ? 255  VAL A CB  1 
ATOM   1270 N  N   . ILE A 1 256 ? 146.817 141.988 104.401 1.00 213.07 ? 256  ILE A N   1 
ATOM   1271 C  CA  . ILE A 1 256 ? 146.009 140.807 104.126 1.00 213.07 ? 256  ILE A CA  1 
ATOM   1272 C  C   . ILE A 1 256 ? 145.015 140.491 105.234 1.00 213.07 ? 256  ILE A C   1 
ATOM   1273 O  O   . ILE A 1 256 ? 143.965 139.891 104.947 1.00 213.07 ? 256  ILE A O   1 
ATOM   1274 C  CB  . ILE A 1 256 ? 146.901 139.578 103.849 1.00 213.07 ? 256  ILE A CB  1 
ATOM   1275 N  N   . ALA A 1 257 ? 145.289 140.862 106.483 1.00 213.76 ? 257  ALA A N   1 
ATOM   1276 C  CA  . ALA A 1 257 ? 144.391 140.593 107.595 1.00 213.76 ? 257  ALA A CA  1 
ATOM   1277 C  C   . ALA A 1 257 ? 144.261 141.835 108.464 1.00 213.76 ? 257  ALA A C   1 
ATOM   1278 O  O   . ALA A 1 257 ? 145.169 142.669 108.524 1.00 213.76 ? 257  ALA A O   1 
ATOM   1279 C  CB  . ALA A 1 257 ? 144.882 139.411 108.442 1.00 213.76 ? 257  ALA A CB  1 
ATOM   1280 N  N   . THR A 1 258 ? 143.119 141.949 109.138 1.00 213.29 ? 258  THR A N   1 
ATOM   1281 C  CA  . THR A 1 258 ? 142.849 143.083 110.009 1.00 213.29 ? 258  THR A CA  1 
ATOM   1282 C  C   . THR A 1 258 ? 141.908 142.645 111.121 1.00 213.29 ? 258  THR A C   1 
ATOM   1283 O  O   . THR A 1 258 ? 141.161 141.675 110.964 1.00 213.29 ? 258  THR A O   1 
ATOM   1284 C  CB  . THR A 1 258 ? 142.238 144.257 109.235 1.00 213.29 ? 258  THR A CB  1 
ATOM   1285 N  N   . GLY A 1 259 ? 141.947 143.367 112.236 1.00 211.28 ? 259  GLY A N   1 
ATOM   1286 C  CA  . GLY A 1 259 ? 141.068 143.042 113.348 1.00 211.28 ? 259  GLY A CA  1 
ATOM   1287 C  C   . GLY A 1 259 ? 141.458 141.725 113.988 1.00 211.28 ? 259  GLY A C   1 
ATOM   1288 O  O   . GLY A 1 259 ? 142.640 141.443 114.214 1.00 211.28 ? 259  GLY A O   1 
ATOM   1289 N  N   . ALA A 1 260 ? 140.451 140.901 114.288 1.00 211.30 ? 260  ALA A N   1 
ATOM   1290 C  CA  . ALA A 1 260 ? 140.701 139.604 114.905 1.00 211.30 ? 260  ALA A CA  1 
ATOM   1291 C  C   . ALA A 1 260 ? 141.390 138.630 113.959 1.00 211.30 ? 260  ALA A C   1 
ATOM   1292 O  O   . ALA A 1 260 ? 141.920 137.612 114.416 1.00 211.30 ? 260  ALA A O   1 
ATOM   1293 C  CB  . ALA A 1 260 ? 139.391 138.998 115.409 1.00 211.30 ? 260  ALA A CB  1 
ATOM   1294 N  N   . ASN A 1 261 ? 141.395 138.916 112.655 1.00 213.24 ? 261  ASN A N   1 
ATOM   1295 C  CA  . ASN A 1 261 ? 142.038 138.036 111.686 1.00 213.24 ? 261  ASN A CA  1 
ATOM   1296 C  C   . ASN A 1 261 ? 143.556 138.024 111.809 1.00 213.24 ? 261  ASN A C   1 
ATOM   1297 O  O   . ASN A 1 261 ? 144.200 137.158 111.207 1.00 213.24 ? 261  ASN A O   1 
ATOM   1298 C  CB  . ASN A 1 261 ? 141.640 138.442 110.266 1.00 213.24 ? 261  ASN A CB  1 
ATOM   1299 N  N   . THR A 1 262 ? 144.139 138.955 112.560 1.00 211.27 ? 262  THR A N   1 
ATOM   1300 C  CA  . THR A 1 262 ? 145.583 138.986 112.734 1.00 211.27 ? 262  THR A CA  1 
ATOM   1301 C  C   . THR A 1 262 ? 146.059 137.768 113.519 1.00 211.27 ? 262  THR A C   1 
ATOM   1302 O  O   . THR A 1 262 ? 145.363 137.257 114.401 1.00 211.27 ? 262  THR A O   1 
ATOM   1303 C  CB  . THR A 1 262 ? 146.010 140.266 113.452 1.00 211.27 ? 262  THR A CB  1 
ATOM   1304 N  N   . TRP A 1 263 ? 147.264 137.301 113.183 1.00 208.78 ? 263  TRP A N   1 
ATOM   1305 C  CA  . TRP A 1 263 ? 147.827 136.141 113.867 1.00 208.78 ? 263  TRP A CA  1 
ATOM   1306 C  C   . TRP A 1 263 ? 148.099 136.443 115.336 1.00 208.78 ? 263  TRP A C   1 
ATOM   1307 O  O   . TRP A 1 263 ? 148.072 135.536 116.176 1.00 208.78 ? 263  TRP A O   1 
ATOM   1308 C  CB  . TRP A 1 263 ? 149.108 135.689 113.167 1.00 208.78 ? 263  TRP A CB  1 
ATOM   1309 N  N   . PHE A 1 264 ? 148.366 137.709 115.664 1.00 205.90 ? 264  PHE A N   1 
ATOM   1310 C  CA  . PHE A 1 264 ? 148.589 138.092 117.053 1.00 205.90 ? 264  PHE A CA  1 
ATOM   1311 C  C   . PHE A 1 264 ? 147.340 137.924 117.908 1.00 205.90 ? 264  PHE A C   1 
ATOM   1312 O  O   . PHE A 1 264 ? 147.453 137.835 119.136 1.00 205.90 ? 264  PHE A O   1 
ATOM   1313 C  CB  . PHE A 1 264 ? 149.080 139.539 117.128 1.00 205.90 ? 264  PHE A CB  1 
ATOM   1314 N  N   . GLY A 1 265 ? 146.167 137.881 117.297 1.00 205.31 ? 265  GLY A N   1 
ATOM   1315 C  CA  . GLY A 1 265 ? 144.917 137.715 118.040 1.00 205.31 ? 265  GLY A CA  1 
ATOM   1316 C  C   . GLY A 1 265 ? 144.360 139.059 118.515 1.00 205.31 ? 265  GLY A C   1 
ATOM   1317 O  O   . GLY A 1 265 ? 143.968 139.888 117.700 1.00 205.31 ? 265  GLY A O   1 
ATOM   1318 N  N   . GLN A 1 266 ? 144.336 139.254 119.834 1.00 201.08 ? 266  GLN A N   1 
ATOM   1319 C  CA  . GLN A 1 266 ? 143.846 140.508 120.393 1.00 201.08 ? 266  GLN A CA  1 
ATOM   1320 C  C   . GLN A 1 266 ? 144.924 141.585 120.354 1.00 201.08 ? 266  GLN A C   1 
ATOM   1321 O  O   . GLN A 1 266 ? 144.737 142.645 119.745 1.00 201.08 ? 266  GLN A O   1 
ATOM   1322 C  CB  . GLN A 1 266 ? 143.354 140.287 121.826 1.00 201.08 ? 266  GLN A CB  1 
ATOM   1323 N  N   . LEU A 1 267 ? 146.055 141.331 121.018 1.00 200.68 ? 267  LEU A N   1 
ATOM   1324 C  CA  . LEU A 1 267 ? 147.198 142.241 121.057 1.00 200.68 ? 267  LEU A CA  1 
ATOM   1325 C  C   . LEU A 1 267 ? 146.841 143.578 121.698 1.00 200.68 ? 267  LEU A C   1 
ATOM   1326 O  O   . LEU A 1 267 ? 147.630 144.527 121.646 1.00 200.68 ? 267  LEU A O   1 
ATOM   1327 C  CB  . LEU A 1 267 ? 147.763 142.461 119.651 1.00 200.68 ? 267  LEU A CB  1 
ATOM   1328 N  N   . ALA A 1 268 ? 145.655 143.665 122.303 1.00 201.40 ? 268  ALA A N   1 
ATOM   1329 C  CA  . ALA A 1 268 ? 145.224 144.884 122.969 1.00 201.40 ? 268  ALA A CA  1 
ATOM   1330 C  C   . ALA A 1 268 ? 144.492 144.633 124.280 1.00 201.40 ? 268  ALA A C   1 
ATOM   1331 O  O   . ALA A 1 268 ? 143.959 145.586 124.856 1.00 201.40 ? 268  ALA A O   1 
ATOM   1332 C  CB  . ALA A 1 268 ? 144.326 145.715 122.038 1.00 201.40 ? 268  ALA A CB  1 
ATOM   1333 N  N   . GLY A 1 269 ? 144.448 143.396 124.768 1.00 199.09 ? 269  GLY A N   1 
ATOM   1334 C  CA  . GLY A 1 269 ? 143.698 143.082 125.968 1.00 199.09 ? 269  GLY A CA  1 
ATOM   1335 C  C   . GLY A 1 269 ? 144.432 143.386 127.257 1.00 199.09 ? 269  GLY A C   1 
ATOM   1336 O  O   . GLY A 1 269 ? 144.560 142.517 128.125 1.00 199.09 ? 269  GLY A O   1 
ATOM   1337 N  N   . ARG A 1 270 ? 144.920 144.617 127.396 1.00 193.97 ? 270  ARG A N   1 
ATOM   1338 C  CA  . ARG A 1 270 ? 145.578 145.056 128.627 1.00 193.97 ? 270  ARG A CA  1 
ATOM   1339 C  C   . ARG A 1 270 ? 144.562 145.713 129.564 1.00 193.97 ? 270  ARG A C   1 
ATOM   1340 O  O   . ARG A 1 270 ? 144.730 146.837 130.035 1.00 193.97 ? 270  ARG A O   1 
ATOM   1341 C  CB  . ARG A 1 270 ? 146.731 145.999 128.302 1.00 193.97 ? 270  ARG A CB  1 
ATOM   1342 N  N   . VAL A 1 271 ? 143.482 144.974 129.823 1.00 190.35 ? 271  VAL A N   1 
ATOM   1343 C  CA  . VAL A 1 271 ? 142.411 145.489 130.671 1.00 190.35 ? 271  VAL A CA  1 
ATOM   1344 C  C   . VAL A 1 271 ? 142.887 145.642 132.110 1.00 190.35 ? 271  VAL A C   1 
ATOM   1345 O  O   . VAL A 1 271 ? 142.602 146.650 132.768 1.00 190.35 ? 271  VAL A O   1 
ATOM   1346 C  CB  . VAL A 1 271 ? 141.174 144.578 130.578 1.00 190.35 ? 271  VAL A CB  1 
ATOM   1347 N  N   . SER A 1 272 ? 143.616 144.653 132.621 1.00 185.67 ? 272  SER A N   1 
ATOM   1348 C  CA  . SER A 1 272 ? 144.069 144.652 134.003 1.00 185.67 ? 272  SER A CA  1 
ATOM   1349 C  C   . SER A 1 272 ? 145.565 144.380 134.058 1.00 185.67 ? 272  SER A C   1 
ATOM   1350 O  O   . SER A 1 272 ? 146.148 143.800 133.139 1.00 185.67 ? 272  SER A O   1 
ATOM   1351 C  CB  . SER A 1 272 ? 143.314 143.610 134.841 1.00 185.67 ? 272  SER A CB  1 
ATOM   1352 N  N   . GLU A 1 273 ? 146.178 144.820 135.159 1.00 175.41 ? 273  GLU A N   1 
ATOM   1353 C  CA  . GLU A 1 273 ? 147.607 144.630 135.415 1.00 175.41 ? 273  GLU A CA  1 
ATOM   1354 C  C   . GLU A 1 273 ? 148.471 145.252 134.322 1.00 175.41 ? 273  GLU A C   1 
ATOM   1355 O  O   . GLU A 1 273 ? 149.550 144.744 134.005 1.00 175.41 ? 273  GLU A O   1 
ATOM   1356 C  CB  . GLU A 1 273 ? 147.950 143.147 135.587 1.00 175.41 ? 273  GLU A CB  1 
ATOM   1357 N  N   . GLN A 1 274 ? 148.001 146.353 133.731 1.00 171.07 ? 274  GLN A N   1 
ATOM   1358 C  CA  . GLN A 1 274 ? 148.803 147.050 132.730 1.00 171.07 ? 274  GLN A CA  1 
ATOM   1359 C  C   . GLN A 1 274 ? 150.066 147.637 133.347 1.00 171.07 ? 274  GLN A C   1 
ATOM   1360 O  O   . GLN A 1 274 ? 151.152 147.539 132.764 1.00 171.07 ? 274  GLN A O   1 
ATOM   1361 C  CB  . GLN A 1 274 ? 147.971 148.143 132.060 1.00 171.07 ? 274  GLN A CB  1 
ATOM   1362 N  N   . GLU A 1 275 ? 149.944 148.249 134.522 1.00 156.53 ? 275  GLU A N   1 
ATOM   1363 C  CA  . GLU A 1 275 ? 151.093 148.810 135.230 1.00 156.53 ? 275  GLU A CA  1 
ATOM   1364 C  C   . GLU A 1 275 ? 151.580 147.815 136.282 1.00 156.53 ? 275  GLU A C   1 
ATOM   1365 O  O   . GLU A 1 275 ? 151.447 148.012 137.490 1.00 156.53 ? 275  GLU A O   1 
ATOM   1366 C  CB  . GLU A 1 275 ? 150.727 150.155 135.851 1.00 156.53 ? 275  GLU A CB  1 
ATOM   1367 N  N   . SER A 1 276 ? 152.150 146.714 135.784 1.00 143.39 ? 276  SER A N   1 
ATOM   1368 C  CA  . SER A 1 276 ? 152.661 145.678 136.676 1.00 143.39 ? 276  SER A CA  1 
ATOM   1369 C  C   . SER A 1 276 ? 153.794 146.208 137.546 1.00 143.39 ? 276  SER A C   1 
ATOM   1370 O  O   . SER A 1 276 ? 153.849 145.925 138.748 1.00 143.39 ? 276  SER A O   1 
ATOM   1371 C  CB  . SER A 1 276 ? 153.126 144.470 135.865 1.00 143.39 ? 276  SER A CB  1 
ATOM   1372 N  N   . GLU A 1 277 ? 154.703 146.975 136.960 1.00 125.79 ? 277  GLU A N   1 
ATOM   1373 C  CA  . GLU A 1 277 ? 155.795 147.557 137.728 1.00 125.79 ? 277  GLU A CA  1 
ATOM   1374 C  C   . GLU A 1 277 ? 155.335 148.858 138.376 1.00 125.79 ? 277  GLU A C   1 
ATOM   1375 O  O   . GLU A 1 277 ? 154.925 149.784 137.669 1.00 125.79 ? 277  GLU A O   1 
ATOM   1376 C  CB  . GLU A 1 277 ? 157.004 147.816 136.835 1.00 125.79 ? 277  GLU A CB  1 
ATOM   1377 N  N   . PRO A 1 278 ? 155.384 148.967 139.704 1.00 104.67 ? 278  PRO A N   1 
ATOM   1378 C  CA  . PRO A 1 278 ? 154.973 150.216 140.355 1.00 104.67 ? 278  PRO A CA  1 
ATOM   1379 C  C   . PRO A 1 278 ? 156.094 151.239 140.382 1.00 104.67 ? 278  PRO A C   1 
ATOM   1380 O  O   . PRO A 1 278 ? 157.176 150.998 139.837 1.00 104.67 ? 278  PRO A O   1 
ATOM   1381 C  CB  . PRO A 1 278 ? 154.590 149.759 141.766 1.00 104.67 ? 278  PRO A CB  1 
ATOM   1382 C  CG  . PRO A 1 278 ? 155.458 148.558 142.016 1.00 104.67 ? 278  PRO A CG  1 
ATOM   1383 C  CD  . PRO A 1 278 ? 155.843 147.960 140.677 1.00 104.67 ? 278  PRO A CD  1 
ATOM   1384 N  N   . ASN A 1 279 ? 155.846 152.386 141.006 1.00 80.13  ? 279  ASN A N   1 
ATOM   1385 C  CA  . ASN A 1 279 ? 156.876 153.406 141.128 1.00 80.13  ? 279  ASN A CA  1 
ATOM   1386 C  C   . ASN A 1 279 ? 158.011 152.905 142.010 1.00 80.13  ? 279  ASN A C   1 
ATOM   1387 O  O   . ASN A 1 279 ? 157.793 152.136 142.950 1.00 80.13  ? 279  ASN A O   1 
ATOM   1388 C  CB  . ASN A 1 279 ? 156.290 154.687 141.717 1.00 80.13  ? 279  ASN A CB  1 
ATOM   1389 C  CG  . ASN A 1 279 ? 155.049 155.147 140.988 1.00 80.13  ? 279  ASN A CG  1 
ATOM   1390 O  OD1 . ASN A 1 279 ? 154.497 154.421 140.162 1.00 80.13  ? 279  ASN A OD1 1 
ATOM   1391 N  ND2 . ASN A 1 279 ? 154.604 156.361 141.287 1.00 80.13  ? 279  ASN A ND2 1 
ATOM   1392 N  N   . ALA A 1 280 ? 159.234 153.338 141.698 1.00 64.50  ? 280  ALA A N   1 
ATOM   1393 C  CA  . ALA A 1 280 ? 160.354 153.057 142.586 1.00 64.50  ? 280  ALA A CA  1 
ATOM   1394 C  C   . ALA A 1 280 ? 160.169 153.715 143.944 1.00 64.50  ? 280  ALA A C   1 
ATOM   1395 O  O   . ALA A 1 280 ? 160.687 153.214 144.945 1.00 64.50  ? 280  ALA A O   1 
ATOM   1396 C  CB  . ALA A 1 280 ? 161.664 153.521 141.950 1.00 64.50  ? 280  ALA A CB  1 
ATOM   1397 N  N   . PHE A 1 281 ? 159.435 154.825 143.992 1.00 59.92  ? 281  PHE A N   1 
ATOM   1398 C  CA  . PHE A 1 281 ? 159.110 155.479 145.254 1.00 59.92  ? 281  PHE A CA  1 
ATOM   1399 C  C   . PHE A 1 281 ? 158.229 154.592 146.130 1.00 59.92  ? 281  PHE A C   1 
ATOM   1400 O  O   . PHE A 1 281 ? 158.536 154.352 147.309 1.00 59.92  ? 281  PHE A O   1 
ATOM   1401 C  CB  . PHE A 1 281 ? 158.425 156.806 144.941 1.00 59.92  ? 281  PHE A CB  1 
ATOM   1402 C  CG  . PHE A 1 281 ? 157.563 157.322 146.035 1.00 59.92  ? 281  PHE A CG  1 
ATOM   1403 C  CD1 . PHE A 1 281 ? 158.111 157.743 147.224 1.00 59.92  ? 281  PHE A CD1 1 
ATOM   1404 C  CD2 . PHE A 1 281 ? 156.195 157.382 145.873 1.00 59.92  ? 281  PHE A CD2 1 
ATOM   1405 C  CE1 . PHE A 1 281 ? 157.309 158.226 148.223 1.00 59.92  ? 281  PHE A CE1 1 
ATOM   1406 C  CE2 . PHE A 1 281 ? 155.391 157.857 146.877 1.00 59.92  ? 281  PHE A CE2 1 
ATOM   1407 C  CZ  . PHE A 1 281 ? 155.948 158.282 148.053 1.00 59.92  ? 281  PHE A CZ  1 
ATOM   1408 N  N   . GLN A 1 282 ? 157.126 154.095 145.568 1.00 65.84  ? 282  GLN A N   1 
ATOM   1409 C  CA  . GLN A 1 282 ? 156.270 153.184 146.317 1.00 65.84  ? 282  GLN A CA  1 
ATOM   1410 C  C   . GLN A 1 282 ? 157.009 151.898 146.653 1.00 65.84  ? 282  GLN A C   1 
ATOM   1411 O  O   . GLN A 1 282 ? 156.769 151.294 147.702 1.00 65.84  ? 282  GLN A O   1 
ATOM   1412 C  CB  . GLN A 1 282 ? 154.998 152.886 145.527 1.00 65.84  ? 282  GLN A CB  1 
ATOM   1413 C  CG  . GLN A 1 282 ? 153.730 152.959 146.357 1.00 65.84  ? 282  GLN A CG  1 
ATOM   1414 C  CD  . GLN A 1 282 ? 152.478 152.784 145.522 1.00 65.84  ? 282  GLN A CD  1 
ATOM   1415 O  OE1 . GLN A 1 282 ? 151.995 153.730 144.902 1.00 65.84  ? 282  GLN A OE1 1 
ATOM   1416 N  NE2 . GLN A 1 282 ? 151.946 151.568 145.502 1.00 65.84  ? 282  GLN A NE2 1 
ATOM   1417 N  N   . GLN A 1 283 ? 157.921 151.469 145.779 1.00 62.40  ? 283  GLN A N   1 
ATOM   1418 C  CA  . GLN A 1 283 ? 158.738 150.298 146.081 1.00 62.40  ? 283  GLN A CA  1 
ATOM   1419 C  C   . GLN A 1 283 ? 159.635 150.555 147.285 1.00 62.40  ? 283  GLN A C   1 
ATOM   1420 O  O   . GLN A 1 283 ? 159.829 149.669 148.127 1.00 62.40  ? 283  GLN A O   1 
ATOM   1421 C  CB  . GLN A 1 283 ? 159.567 149.912 144.856 1.00 62.40  ? 283  GLN A CB  1 
ATOM   1422 C  CG  . GLN A 1 283 ? 160.216 148.538 144.940 1.00 62.40  ? 283  GLN A CG  1 
ATOM   1423 C  CD  . GLN A 1 283 ? 161.712 148.608 145.181 1.00 62.40  ? 283  GLN A CD  1 
ATOM   1424 O  OE1 . GLN A 1 283 ? 162.405 149.453 144.616 1.00 62.40  ? 283  GLN A OE1 1 
ATOM   1425 N  NE2 . GLN A 1 283 ? 162.219 147.708 146.016 1.00 62.40  ? 283  GLN A NE2 1 
ATOM   1426 N  N   . GLY A 1 284 ? 160.197 151.761 147.381 1.00 57.01  ? 284  GLY A N   1 
ATOM   1427 C  CA  . GLY A 1 284 ? 160.997 152.100 148.544 1.00 57.01  ? 284  GLY A CA  1 
ATOM   1428 C  C   . GLY A 1 284 ? 160.186 152.093 149.823 1.00 57.01  ? 284  GLY A C   1 
ATOM   1429 O  O   . GLY A 1 284 ? 160.616 151.544 150.844 1.00 57.01  ? 284  GLY A O   1 
ATOM   1430 N  N   . ILE A 1 285 ? 158.997 152.695 149.785 1.00 55.72  ? 285  ILE A N   1 
ATOM   1431 C  CA  . ILE A 1 285 ? 158.128 152.654 150.961 1.00 55.72  ? 285  ILE A CA  1 
ATOM   1432 C  C   . ILE A 1 285 ? 157.789 151.212 151.320 1.00 55.72  ? 285  ILE A C   1 
ATOM   1433 O  O   . ILE A 1 285 ? 157.771 150.835 152.499 1.00 55.72  ? 285  ILE A O   1 
ATOM   1434 C  CB  . ILE A 1 285 ? 156.859 153.496 150.735 1.00 55.72  ? 285  ILE A CB  1 
ATOM   1435 C  CG1 . ILE A 1 285 ? 157.137 154.966 151.026 1.00 55.72  ? 285  ILE A CG1 1 
ATOM   1436 C  CG2 . ILE A 1 285 ? 155.725 153.009 151.615 1.00 55.72  ? 285  ILE A CG2 1 
ATOM   1437 C  CD1 . ILE A 1 285 ? 156.062 155.879 150.522 1.00 55.72  ? 285  ILE A CD1 1 
ATOM   1438 N  N   . SER A 1 286 ? 157.528 150.381 150.309 1.00 57.97  ? 286  SER A N   1 
ATOM   1439 C  CA  . SER A 1 286 ? 157.159 148.994 150.562 1.00 57.97  ? 286  SER A CA  1 
ATOM   1440 C  C   . SER A 1 286 ? 158.298 148.218 151.208 1.00 57.97  ? 286  SER A C   1 
ATOM   1441 O  O   . SER A 1 286 ? 158.070 147.434 152.132 1.00 57.97  ? 286  SER A O   1 
ATOM   1442 C  CB  . SER A 1 286 ? 156.722 148.324 149.261 1.00 57.97  ? 286  SER A CB  1 
ATOM   1443 O  OG  . SER A 1 286 ? 155.370 148.627 148.968 1.00 57.97  ? 286  SER A OG  1 
ATOM   1444 N  N   . ARG A 1 287 ? 159.534 148.415 150.744 1.00 55.50  ? 287  ARG A N   1 
ATOM   1445 C  CA  . ARG A 1 287 ? 160.640 147.681 151.355 1.00 55.50  ? 287  ARG A CA  1 
ATOM   1446 C  C   . ARG A 1 287 ? 160.940 148.194 152.761 1.00 55.50  ? 287  ARG A C   1 
ATOM   1447 O  O   . ARG A 1 287 ? 161.302 147.409 153.651 1.00 55.50  ? 287  ARG A O   1 
ATOM   1448 C  CB  . ARG A 1 287 ? 161.889 147.734 150.472 1.00 55.50  ? 287  ARG A CB  1 
ATOM   1449 C  CG  . ARG A 1 287 ? 162.484 149.108 150.244 1.00 55.50  ? 287  ARG A CG  1 
ATOM   1450 C  CD  . ARG A 1 287 ? 162.968 149.251 148.810 1.00 55.50  ? 287  ARG A CD  1 
ATOM   1451 N  NE  . ARG A 1 287 ? 164.007 148.283 148.482 1.00 55.50  ? 287  ARG A NE  1 
ATOM   1452 C  CZ  . ARG A 1 287 ? 165.287 148.425 148.796 1.00 55.50  ? 287  ARG A CZ  1 
ATOM   1453 N  NH1 . ARG A 1 287 ? 165.727 149.501 149.426 1.00 55.50  ? 287  ARG A NH1 1 
ATOM   1454 N  NH2 . ARG A 1 287 ? 166.147 147.468 148.464 1.00 55.50  ? 287  ARG A NH2 1 
ATOM   1455 N  N   . VAL A 1 288 ? 160.777 149.501 152.993 1.00 48.45  ? 288  VAL A N   1 
ATOM   1456 C  CA  . VAL A 1 288 ? 160.933 150.022 154.350 1.00 48.45  ? 288  VAL A CA  1 
ATOM   1457 C  C   . VAL A 1 288 ? 159.906 149.387 155.277 1.00 48.45  ? 288  VAL A C   1 
ATOM   1458 O  O   . VAL A 1 288 ? 160.229 148.958 156.390 1.00 48.45  ? 288  VAL A O   1 
ATOM   1459 C  CB  . VAL A 1 288 ? 160.826 151.555 154.361 1.00 48.45  ? 288  VAL A CB  1 
ATOM   1460 C  CG1 . VAL A 1 288 ? 160.728 152.055 155.787 1.00 48.45  ? 288  VAL A CG1 1 
ATOM   1461 C  CG2 . VAL A 1 288 ? 162.028 152.161 153.682 1.00 48.45  ? 288  VAL A CG2 1 
ATOM   1462 N  N   . SER A 1 289 ? 158.653 149.307 154.826 1.00 48.01  ? 289  SER A N   1 
ATOM   1463 C  CA  . SER A 1 289 ? 157.625 148.655 155.628 1.00 48.01  ? 289  SER A CA  1 
ATOM   1464 C  C   . SER A 1 289 ? 157.913 147.171 155.806 1.00 48.01  ? 289  SER A C   1 
ATOM   1465 O  O   . SER A 1 289 ? 157.585 146.594 156.849 1.00 48.01  ? 289  SER A O   1 
ATOM   1466 C  CB  . SER A 1 289 ? 156.256 148.853 154.986 1.00 48.01  ? 289  SER A CB  1 
ATOM   1467 O  OG  . SER A 1 289 ? 155.292 148.023 155.602 1.00 48.01  ? 289  SER A OG  1 
ATOM   1468 N  N   . MET A 1 290 ? 158.516 146.538 154.800 1.00 48.53  ? 290  MET A N   1 
ATOM   1469 C  CA  . MET A 1 290 ? 158.854 145.125 154.905 1.00 48.53  ? 290  MET A CA  1 
ATOM   1470 C  C   . MET A 1 290 ? 159.906 144.886 155.976 1.00 48.53  ? 290  MET A C   1 
ATOM   1471 O  O   . MET A 1 290 ? 159.868 143.865 156.667 1.00 48.53  ? 290  MET A O   1 
ATOM   1472 C  CB  . MET A 1 290 ? 159.337 144.596 153.556 1.00 48.53  ? 290  MET A CB  1 
ATOM   1473 C  CG  . MET A 1 290 ? 159.263 143.084 153.423 1.00 48.53  ? 290  MET A CG  1 
ATOM   1474 S  SD  . MET A 1 290 ? 157.602 142.409 153.597 1.00 48.53  ? 290  MET A SD  1 
ATOM   1475 C  CE  . MET A 1 290 ? 156.653 143.561 152.610 1.00 48.53  ? 290  MET A CE  1 
ATOM   1476 N  N   . LEU A 1 291 ? 160.862 145.804 156.118 1.00 42.06  ? 291  LEU A N   1 
ATOM   1477 C  CA  . LEU A 1 291 ? 161.851 145.650 157.184 1.00 42.06  ? 291  LEU A CA  1 
ATOM   1478 C  C   . LEU A 1 291 ? 161.189 145.659 158.559 1.00 42.06  ? 291  LEU A C   1 
ATOM   1479 O  O   . LEU A 1 291 ? 161.497 144.820 159.418 1.00 42.06  ? 291  LEU A O   1 
ATOM   1480 C  CB  . LEU A 1 291 ? 162.905 146.750 157.095 1.00 42.06  ? 291  LEU A CB  1 
ATOM   1481 C  CG  . LEU A 1 291 ? 164.027 146.642 158.126 1.00 42.06  ? 291  LEU A CG  1 
ATOM   1482 C  CD1 . LEU A 1 291 ? 164.762 145.326 157.979 1.00 42.06  ? 291  LEU A CD1 1 
ATOM   1483 C  CD2 . LEU A 1 291 ? 164.987 147.798 157.981 1.00 42.06  ? 291  LEU A CD2 1 
ATOM   1484 N  N   . LEU A 1 292 ? 160.262 146.591 158.781 1.00 40.76  ? 292  LEU A N   1 
ATOM   1485 C  CA  . LEU A 1 292 ? 159.587 146.661 160.072 1.00 40.76  ? 292  LEU A CA  1 
ATOM   1486 C  C   . LEU A 1 292 ? 158.674 145.461 160.284 1.00 40.76  ? 292  LEU A C   1 
ATOM   1487 O  O   . LEU A 1 292 ? 158.540 144.971 161.409 1.00 40.76  ? 292  LEU A O   1 
ATOM   1488 C  CB  . LEU A 1 292 ? 158.811 147.969 160.183 1.00 40.76  ? 292  LEU A CB  1 
ATOM   1489 C  CG  . LEU A 1 292 ? 159.703 149.200 160.028 1.00 40.76  ? 292  LEU A CG  1 
ATOM   1490 C  CD1 . LEU A 1 292 ? 158.899 150.466 160.171 1.00 40.76  ? 292  LEU A CD1 1 
ATOM   1491 C  CD2 . LEU A 1 292 ? 160.837 149.170 161.033 1.00 40.76  ? 292  LEU A CD2 1 
ATOM   1492 N  N   . ILE A 1 293 ? 158.041 144.969 159.218 1.00 45.27  ? 293  ILE A N   1 
ATOM   1493 C  CA  . ILE A 1 293 ? 157.240 143.753 159.338 1.00 45.27  ? 293  ILE A CA  1 
ATOM   1494 C  C   . ILE A 1 293 ? 158.124 142.573 159.720 1.00 45.27  ? 293  ILE A C   1 
ATOM   1495 O  O   . ILE A 1 293 ? 157.750 141.741 160.558 1.00 45.27  ? 293  ILE A O   1 
ATOM   1496 C  CB  . ILE A 1 293 ? 156.467 143.492 158.033 1.00 45.27  ? 293  ILE A CB  1 
ATOM   1497 C  CG1 . ILE A 1 293 ? 155.304 144.475 157.909 1.00 45.27  ? 293  ILE A CG1 1 
ATOM   1498 C  CG2 . ILE A 1 293 ? 155.963 142.063 157.986 1.00 45.27  ? 293  ILE A CG2 1 
ATOM   1499 C  CD1 . ILE A 1 293 ? 154.604 144.427 156.576 1.00 45.27  ? 293  ILE A CD1 1 
ATOM   1500 N  N   . ARG A 1 294 ? 159.311 142.483 159.116 1.00 42.54  ? 294  ARG A N   1 
ATOM   1501 C  CA  . ARG A 1 294 ? 160.267 141.451 159.498 1.00 42.54  ? 294  ARG A CA  1 
ATOM   1502 C  C   . ARG A 1 294 ? 160.594 141.545 160.979 1.00 42.54  ? 294  ARG A C   1 
ATOM   1503 O  O   . ARG A 1 294 ? 160.597 140.537 161.692 1.00 42.54  ? 294  ARG A O   1 
ATOM   1504 C  CB  . ARG A 1 294 ? 161.545 141.580 158.670 1.00 42.54  ? 294  ARG A CB  1 
ATOM   1505 C  CG  . ARG A 1 294 ? 161.467 141.019 157.265 1.00 42.54  ? 294  ARG A CG  1 
ATOM   1506 C  CD  . ARG A 1 294 ? 162.849 140.994 156.635 1.00 42.54  ? 294  ARG A CD  1 
ATOM   1507 N  NE  . ARG A 1 294 ? 162.834 140.482 155.271 1.00 42.54  ? 294  ARG A NE  1 
ATOM   1508 C  CZ  . ARG A 1 294 ? 163.118 141.206 154.198 1.00 42.54  ? 294  ARG A CZ  1 
ATOM   1509 N  NH1 . ARG A 1 294 ? 163.438 142.487 154.293 1.00 42.54  ? 294  ARG A NH1 1 
ATOM   1510 N  NH2 . ARG A 1 294 ? 163.083 140.632 152.999 1.00 42.54  ? 294  ARG A NH2 1 
ATOM   1511 N  N   . PHE A 1 295 ? 160.868 142.758 161.461 1.00 40.81  ? 295  PHE A N   1 
ATOM   1512 C  CA  . PHE A 1 295 ? 161.190 142.914 162.876 1.00 40.81  ? 295  PHE A CA  1 
ATOM   1513 C  C   . PHE A 1 295 ? 160.021 142.524 163.772 1.00 40.81  ? 295  PHE A C   1 
ATOM   1514 O  O   . PHE A 1 295 ? 160.228 141.907 164.823 1.00 40.81  ? 295  PHE A O   1 
ATOM   1515 C  CB  . PHE A 1 295 ? 161.635 144.343 163.174 1.00 40.81  ? 295  PHE A CB  1 
ATOM   1516 C  CG  . PHE A 1 295 ? 163.120 144.535 163.111 1.00 40.81  ? 295  PHE A CG  1 
ATOM   1517 C  CD1 . PHE A 1 295 ? 163.886 143.810 162.220 1.00 40.81  ? 295  PHE A CD1 1 
ATOM   1518 C  CD2 . PHE A 1 295 ? 163.751 145.421 163.960 1.00 40.81  ? 295  PHE A CD2 1 
ATOM   1519 C  CE1 . PHE A 1 295 ? 165.252 143.981 162.166 1.00 40.81  ? 295  PHE A CE1 1 
ATOM   1520 C  CE2 . PHE A 1 295 ? 165.115 145.590 163.914 1.00 40.81  ? 295  PHE A CE2 1 
ATOM   1521 C  CZ  . PHE A 1 295 ? 165.866 144.874 163.013 1.00 40.81  ? 295  PHE A CZ  1 
ATOM   1522 N  N   . MET A 1 296 ? 158.793 142.873 163.386 1.00 43.91  ? 296  MET A N   1 
ATOM   1523 C  CA  . MET A 1 296 ? 157.632 142.484 164.182 1.00 43.91  ? 296  MET A CA  1 
ATOM   1524 C  C   . MET A 1 296 ? 157.490 140.969 164.242 1.00 43.91  ? 296  MET A C   1 
ATOM   1525 O  O   . MET A 1 296 ? 157.229 140.399 165.307 1.00 43.91  ? 296  MET A O   1 
ATOM   1526 C  CB  . MET A 1 296 ? 156.359 143.106 163.613 1.00 43.91  ? 296  MET A CB  1 
ATOM   1527 C  CG  . MET A 1 296 ? 156.345 144.614 163.577 1.00 43.91  ? 296  MET A CG  1 
ATOM   1528 S  SD  . MET A 1 296 ? 154.870 145.259 162.769 1.00 43.91  ? 296  MET A SD  1 
ATOM   1529 C  CE  . MET A 1 296 ? 153.838 143.797 162.735 1.00 43.91  ? 296  MET A CE  1 
ATOM   1530 N  N   . LEU A 1 297 ? 157.660 140.298 163.103 1.00 45.83  ? 297  LEU A N   1 
ATOM   1531 C  CA  . LEU A 1 297 ? 157.435 138.860 163.036 1.00 45.83  ? 297  LEU A CA  1 
ATOM   1532 C  C   . LEU A 1 297 ? 158.459 138.059 163.828 1.00 45.83  ? 297  LEU A C   1 
ATOM   1533 O  O   . LEU A 1 297 ? 158.229 136.872 164.076 1.00 45.83  ? 297  LEU A O   1 
ATOM   1534 C  CB  . LEU A 1 297 ? 157.436 138.401 161.578 1.00 45.83  ? 297  LEU A CB  1 
ATOM   1535 C  CG  . LEU A 1 297 ? 156.150 138.661 160.791 1.00 45.83  ? 297  LEU A CG  1 
ATOM   1536 C  CD1 . LEU A 1 297 ? 155.993 137.649 159.668 1.00 45.83  ? 297  LEU A CD1 1 
ATOM   1537 C  CD2 . LEU A 1 297 ? 154.935 138.644 161.706 1.00 45.83  ? 297  LEU A CD2 1 
ATOM   1538 N  N   . VAL A 1 298 ? 159.576 138.669 164.222 1.00 43.30  ? 298  VAL A N   1 
ATOM   1539 C  CA  . VAL A 1 298 ? 160.589 137.996 165.027 1.00 43.30  ? 298  VAL A CA  1 
ATOM   1540 C  C   . VAL A 1 298 ? 160.630 138.518 166.456 1.00 43.30  ? 298  VAL A C   1 
ATOM   1541 O  O   . VAL A 1 298 ? 161.301 137.909 167.305 1.00 43.30  ? 298  VAL A O   1 
ATOM   1542 C  CB  . VAL A 1 298 ? 161.986 138.106 164.376 1.00 43.30  ? 298  VAL A CB  1 
ATOM   1543 C  CG1 . VAL A 1 298 ? 162.971 137.127 164.997 1.00 43.30  ? 298  VAL A CG1 1 
ATOM   1544 C  CG2 . VAL A 1 298 ? 161.888 137.870 162.883 1.00 43.30  ? 298  VAL A CG2 1 
ATOM   1545 N  N   . MET A 1 299 ? 159.919 139.598 166.761 1.00 43.89  ? 299  MET A N   1 
ATOM   1546 C  CA  . MET A 1 299 ? 159.931 140.183 168.095 1.00 43.89  ? 299  MET A CA  1 
ATOM   1547 C  C   . MET A 1 299 ? 158.602 140.073 168.824 1.00 43.89  ? 299  MET A C   1 
ATOM   1548 O  O   . MET A 1 299 ? 158.592 139.863 170.037 1.00 43.89  ? 299  MET A O   1 
ATOM   1549 C  CB  . MET A 1 299 ? 160.347 141.655 168.017 1.00 43.89  ? 299  MET A CB  1 
ATOM   1550 C  CG  . MET A 1 299 ? 161.064 142.153 169.250 1.00 43.89  ? 299  MET A CG  1 
ATOM   1551 S  SD  . MET A 1 299 ? 161.910 143.719 168.989 1.00 43.89  ? 299  MET A SD  1 
ATOM   1552 C  CE  . MET A 1 299 ? 161.888 143.820 167.203 1.00 43.89  ? 299  MET A CE  1 
ATOM   1553 N  N   . ALA A 1 300 ? 157.477 140.216 168.124 1.00 43.23  ? 300  ALA A N   1 
ATOM   1554 C  CA  . ALA A 1 300 ? 156.184 140.064 168.785 1.00 43.23  ? 300  ALA A CA  1 
ATOM   1555 C  C   . ALA A 1 300 ? 155.940 138.651 169.310 1.00 43.23  ? 300  ALA A C   1 
ATOM   1556 O  O   . ALA A 1 300 ? 155.475 138.527 170.457 1.00 43.23  ? 300  ALA A O   1 
ATOM   1557 C  CB  . ALA A 1 300 ? 155.059 140.516 167.844 1.00 43.23  ? 300  ALA A CB  1 
ATOM   1558 N  N   . PRO A 1 301 ? 156.194 137.570 168.556 1.00 45.58  ? 301  PRO A N   1 
ATOM   1559 C  CA  . PRO A 1 301 ? 156.071 136.235 169.166 1.00 45.58  ? 301  PRO A CA  1 
ATOM   1560 C  C   . PRO A 1 301 ? 156.967 136.047 170.375 1.00 45.58  ? 301  PRO A C   1 
ATOM   1561 O  O   . PRO A 1 301 ? 156.573 135.381 171.340 1.00 45.58  ? 301  PRO A O   1 
ATOM   1562 C  CB  . PRO A 1 301 ? 156.470 135.278 168.031 1.00 45.58  ? 301  PRO A CB  1 
ATOM   1563 C  CG  . PRO A 1 301 ? 156.817 136.122 166.861 1.00 45.58  ? 301  PRO A CG  1 
ATOM   1564 C  CD  . PRO A 1 301 ? 156.281 137.485 167.090 1.00 45.58  ? 301  PRO A CD  1 
ATOM   1565 N  N   . VAL A 1 302 ? 158.172 136.618 170.349 1.00 43.56  ? 302  VAL A N   1 
ATOM   1566 C  CA  . VAL A 1 302 ? 159.081 136.466 171.479 1.00 43.56  ? 302  VAL A CA  1 
ATOM   1567 C  C   . VAL A 1 302 ? 158.492 137.112 172.726 1.00 43.56  ? 302  VAL A C   1 
ATOM   1568 O  O   . VAL A 1 302 ? 158.520 136.528 173.814 1.00 43.56  ? 302  VAL A O   1 
ATOM   1569 C  CB  . VAL A 1 302 ? 160.466 137.040 171.132 1.00 43.56  ? 302  VAL A CB  1 
ATOM   1570 C  CG1 . VAL A 1 302 ? 161.315 137.165 172.378 1.00 43.56  ? 302  VAL A CG1 1 
ATOM   1571 C  CG2 . VAL A 1 302 ? 161.157 136.153 170.115 1.00 43.56  ? 302  VAL A CG2 1 
ATOM   1572 N  N   . VAL A 1 303 ? 157.945 138.322 172.588 1.00 45.05  ? 303  VAL A N   1 
ATOM   1573 C  CA  . VAL A 1 303 ? 157.289 138.978 173.717 1.00 45.05  ? 303  VAL A CA  1 
ATOM   1574 C  C   . VAL A 1 303 ? 156.102 138.154 174.189 1.00 45.05  ? 303  VAL A C   1 
ATOM   1575 O  O   . VAL A 1 303 ? 155.900 137.957 175.396 1.00 45.05  ? 303  VAL A O   1 
ATOM   1576 C  CB  . VAL A 1 303 ? 156.862 140.405 173.332 1.00 45.05  ? 303  VAL A CB  1 
ATOM   1577 C  CG1 . VAL A 1 303 ? 155.820 140.928 174.302 1.00 45.05  ? 303  VAL A CG1 1 
ATOM   1578 C  CG2 . VAL A 1 303 ? 158.065 141.320 173.298 1.00 45.05  ? 303  VAL A CG2 1 
ATOM   1579 N  N   . LEU A 1 304 ? 155.296 137.665 173.243 1.00 46.46  ? 304  LEU A N   1 
ATOM   1580 C  CA  . LEU A 1 304 ? 154.161 136.814 173.584 1.00 46.46  ? 304  LEU A CA  1 
ATOM   1581 C  C   . LEU A 1 304 ? 154.606 135.626 174.426 1.00 46.46  ? 304  LEU A C   1 
ATOM   1582 O  O   . LEU A 1 304 ? 153.901 135.209 175.352 1.00 46.46  ? 304  LEU A O   1 
ATOM   1583 C  CB  . LEU A 1 304 ? 153.478 136.345 172.300 1.00 46.46  ? 304  LEU A CB  1 
ATOM   1584 C  CG  . LEU A 1 304 ? 152.406 135.256 172.321 1.00 46.46  ? 304  LEU A CG  1 
ATOM   1585 C  CD1 . LEU A 1 304 ? 151.402 135.481 173.434 1.00 46.46  ? 304  LEU A CD1 1 
ATOM   1586 C  CD2 . LEU A 1 304 ? 151.708 135.184 170.973 1.00 46.46  ? 304  LEU A CD2 1 
ATOM   1587 N  N   . LEU A 1 305 ? 155.779 135.074 174.123 1.00 47.00  ? 305  LEU A N   1 
ATOM   1588 C  CA  . LEU A 1 305 ? 156.286 133.953 174.906 1.00 47.00  ? 305  LEU A CA  1 
ATOM   1589 C  C   . LEU A 1 305 ? 156.743 134.397 176.291 1.00 47.00  ? 305  LEU A C   1 
ATOM   1590 O  O   . LEU A 1 305 ? 156.245 133.887 177.302 1.00 47.00  ? 305  LEU A O   1 
ATOM   1591 C  CB  . LEU A 1 305 ? 157.425 133.260 174.162 1.00 47.00  ? 305  LEU A CB  1 
ATOM   1592 C  CG  . LEU A 1 305 ? 157.071 132.004 173.359 1.00 47.00  ? 305  LEU A CG  1 
ATOM   1593 C  CD1 . LEU A 1 305 ? 155.895 132.249 172.427 1.00 47.00  ? 305  LEU A CD1 1 
ATOM   1594 C  CD2 . LEU A 1 305 ? 158.280 131.513 172.581 1.00 47.00  ? 305  LEU A CD2 1 
ATOM   1595 N  N   . ILE A 1 306 ? 157.680 135.351 176.362 1.00 48.88  ? 306  ILE A N   1 
ATOM   1596 C  CA  . ILE A 1 306 ? 158.269 135.701 177.659 1.00 48.88  ? 306  ILE A CA  1 
ATOM   1597 C  C   . ILE A 1 306 ? 157.203 136.196 178.622 1.00 48.88  ? 306  ILE A C   1 
ATOM   1598 O  O   . ILE A 1 306 ? 157.151 135.763 179.779 1.00 48.88  ? 306  ILE A O   1 
ATOM   1599 C  CB  . ILE A 1 306 ? 159.409 136.730 177.524 1.00 48.88  ? 306  ILE A CB  1 
ATOM   1600 C  CG1 . ILE A 1 306 ? 160.143 136.609 176.196 1.00 48.88  ? 306  ILE A CG1 1 
ATOM   1601 C  CG2 . ILE A 1 306 ? 160.387 136.594 178.681 1.00 48.88  ? 306  ILE A CG2 1 
ATOM   1602 C  CD1 . ILE A 1 306 ? 161.085 137.759 175.927 1.00 48.88  ? 306  ILE A CD1 1 
ATOM   1603 N  N   . ASN A 1 307 ? 156.342 137.103 178.181 1.00 51.68  ? 307  ASN A N   1 
ATOM   1604 C  CA  . ASN A 1 307 ? 155.235 137.551 179.016 1.00 51.68  ? 307  ASN A CA  1 
ATOM   1605 C  C   . ASN A 1 307 ? 153.996 136.837 178.497 1.00 51.68  ? 307  ASN A C   1 
ATOM   1606 O  O   . ASN A 1 307 ? 153.452 137.195 177.450 1.00 51.68  ? 307  ASN A O   1 
ATOM   1607 C  CB  . ASN A 1 307 ? 155.084 139.064 178.991 1.00 51.68  ? 307  ASN A CB  1 
ATOM   1608 C  CG  . ASN A 1 307 ? 154.225 139.569 180.125 1.00 51.68  ? 307  ASN A CG  1 
ATOM   1609 O  OD1 . ASN A 1 307 ? 153.599 138.787 180.838 1.00 51.68  ? 307  ASN A OD1 1 
ATOM   1610 N  ND2 . ASN A 1 307 ? 154.207 140.877 180.314 1.00 51.68  ? 307  ASN A ND2 1 
ATOM   1611 N  N   . GLY A 1 308 ? 153.558 135.827 179.241 1.00 61.20  ? 308  GLY A N   1 
ATOM   1612 C  CA  . GLY A 1 308 ? 152.545 134.898 178.788 1.00 61.20  ? 308  GLY A CA  1 
ATOM   1613 C  C   . GLY A 1 308 ? 152.913 133.495 179.216 1.00 61.20  ? 308  GLY A C   1 
ATOM   1614 O  O   . GLY A 1 308 ? 152.043 132.654 179.459 1.00 61.20  ? 308  GLY A O   1 
ATOM   1615 N  N   . TYR A 1 309 ? 154.218 133.233 179.312 1.00 62.95  ? 309  TYR A N   1 
ATOM   1616 C  CA  . TYR A 1 309 ? 154.675 132.029 179.993 1.00 62.95  ? 309  TYR A CA  1 
ATOM   1617 C  C   . TYR A 1 309 ? 155.068 132.341 181.430 1.00 62.95  ? 309  TYR A C   1 
ATOM   1618 O  O   . TYR A 1 309 ? 154.805 131.547 182.340 1.00 62.95  ? 309  TYR A O   1 
ATOM   1619 C  CB  . TYR A 1 309 ? 155.844 131.408 179.229 1.00 62.95  ? 309  TYR A CB  1 
ATOM   1620 C  CG  . TYR A 1 309 ? 156.828 130.649 180.091 1.00 62.95  ? 309  TYR A CG  1 
ATOM   1621 C  CD1 . TYR A 1 309 ? 156.471 129.458 180.709 1.00 62.95  ? 309  TYR A CD1 1 
ATOM   1622 C  CD2 . TYR A 1 309 ? 158.118 131.125 180.283 1.00 62.95  ? 309  TYR A CD2 1 
ATOM   1623 C  CE1 . TYR A 1 309 ? 157.371 128.764 181.497 1.00 62.95  ? 309  TYR A CE1 1 
ATOM   1624 C  CE2 . TYR A 1 309 ? 159.023 130.439 181.067 1.00 62.95  ? 309  TYR A CE2 1 
ATOM   1625 C  CZ  . TYR A 1 309 ? 158.646 129.259 181.672 1.00 62.95  ? 309  TYR A CZ  1 
ATOM   1626 O  OH  . TYR A 1 309 ? 159.547 128.574 182.454 1.00 62.95  ? 309  TYR A OH  1 
ATOM   1627 N  N   . THR A 1 310 ? 155.696 133.498 181.651 1.00 58.21  ? 310  THR A N   1 
ATOM   1628 C  CA  . THR A 1 310 ? 156.070 133.897 183.004 1.00 58.21  ? 310  THR A CA  1 
ATOM   1629 C  C   . THR A 1 310 ? 154.842 134.149 183.870 1.00 58.21  ? 310  THR A C   1 
ATOM   1630 O  O   . THR A 1 310 ? 154.805 133.740 185.036 1.00 58.21  ? 310  THR A O   1 
ATOM   1631 C  CB  . THR A 1 310 ? 156.950 135.145 182.960 1.00 58.21  ? 310  THR A CB  1 
ATOM   1632 O  OG1 . THR A 1 310 ? 157.896 135.026 181.892 1.00 58.21  ? 310  THR A OG1 1 
ATOM   1633 C  CG2 . THR A 1 310 ? 157.695 135.311 184.272 1.00 58.21  ? 310  THR A CG2 1 
ATOM   1634 N  N   . LYS A 1 311 ? 153.830 134.818 183.322 1.00 59.26  ? 311  LYS A N   1 
ATOM   1635 C  CA  . LYS A 1 311 ? 152.635 135.169 184.077 1.00 59.26  ? 311  LYS A CA  1 
ATOM   1636 C  C   . LYS A 1 311 ? 151.494 134.183 183.882 1.00 59.26  ? 311  LYS A C   1 
ATOM   1637 O  O   . LYS A 1 311 ? 150.858 133.780 184.860 1.00 59.26  ? 311  LYS A O   1 
ATOM   1638 C  CB  . LYS A 1 311 ? 152.163 136.574 183.695 1.00 59.26  ? 311  LYS A CB  1 
ATOM   1639 C  CG  . LYS A 1 311 ? 153.082 137.685 184.169 1.00 59.26  ? 311  LYS A CG  1 
ATOM   1640 C  CD  . LYS A 1 311 ? 153.387 137.557 185.652 1.00 59.26  ? 311  LYS A CD  1 
ATOM   1641 C  CE  . LYS A 1 311 ? 154.391 138.607 186.101 1.00 59.26  ? 311  LYS A CE  1 
ATOM   1642 N  NZ  . LYS A 1 311 ? 155.676 138.507 185.355 1.00 59.26  ? 311  LYS A NZ  1 
ATOM   1643 N  N   . GLY A 1 312 ? 151.219 133.780 182.645 1.00 63.39  ? 312  GLY A N   1 
ATOM   1644 C  CA  . GLY A 1 312 ? 150.150 132.850 182.355 1.00 63.39  ? 312  GLY A CA  1 
ATOM   1645 C  C   . GLY A 1 312 ? 148.879 133.480 181.828 1.00 63.39  ? 312  GLY A C   1 
ATOM   1646 O  O   . GLY A 1 312 ? 147.997 132.750 181.360 1.00 63.39  ? 312  GLY A O   1 
ATOM   1647 N  N   . ASP A 1 313 ? 148.757 134.804 181.888 1.00 64.37  ? 313  ASP A N   1 
ATOM   1648 C  CA  . ASP A 1 313 ? 147.589 135.506 181.359 1.00 64.37  ? 313  ASP A CA  1 
ATOM   1649 C  C   . ASP A 1 313 ? 147.807 135.720 179.867 1.00 64.37  ? 313  ASP A C   1 
ATOM   1650 O  O   . ASP A 1 313 ? 148.385 136.726 179.448 1.00 64.37  ? 313  ASP A O   1 
ATOM   1651 C  CB  . ASP A 1 313 ? 147.376 136.827 182.089 1.00 64.37  ? 313  ASP A CB  1 
ATOM   1652 C  CG  . ASP A 1 313 ? 146.011 137.423 181.823 1.00 64.37  ? 313  ASP A CG  1 
ATOM   1653 O  OD1 . ASP A 1 313 ? 145.216 136.788 181.099 1.00 64.37  ? 313  ASP A OD1 1 
ATOM   1654 O  OD2 . ASP A 1 313 ? 145.733 138.527 182.335 1.00 64.37  ? 313  ASP A OD2 1 
ATOM   1655 N  N   . TRP A 1 314 ? 147.337 134.770 179.058 1.00 69.25  ? 314  TRP A N   1 
ATOM   1656 C  CA  . TRP A 1 314 ? 147.606 134.819 177.628 1.00 69.25  ? 314  TRP A CA  1 
ATOM   1657 C  C   . TRP A 1 314 ? 146.816 135.905 176.912 1.00 69.25  ? 314  TRP A C   1 
ATOM   1658 O  O   . TRP A 1 314 ? 147.232 136.338 175.833 1.00 69.25  ? 314  TRP A O   1 
ATOM   1659 C  CB  . TRP A 1 314 ? 147.333 133.454 176.999 1.00 69.25  ? 314  TRP A CB  1 
ATOM   1660 C  CG  . TRP A 1 314 ? 148.462 132.497 177.207 1.00 69.25  ? 314  TRP A CG  1 
ATOM   1661 C  CD1 . TRP A 1 314 ? 149.730 132.806 177.596 1.00 69.25  ? 314  TRP A CD1 1 
ATOM   1662 C  CD2 . TRP A 1 314 ? 148.426 131.074 177.046 1.00 69.25  ? 314  TRP A CD2 1 
ATOM   1663 N  NE1 . TRP A 1 314 ? 150.491 131.666 177.683 1.00 69.25  ? 314  TRP A NE1 1 
ATOM   1664 C  CE2 . TRP A 1 314 ? 149.713 130.589 177.351 1.00 69.25  ? 314  TRP A CE2 1 
ATOM   1665 C  CE3 . TRP A 1 314 ? 147.433 130.164 176.672 1.00 69.25  ? 314  TRP A CE3 1 
ATOM   1666 C  CZ2 . TRP A 1 314 ? 150.032 129.234 177.294 1.00 69.25  ? 314  TRP A CZ2 1 
ATOM   1667 C  CZ3 . TRP A 1 314 ? 147.752 128.819 176.615 1.00 69.25  ? 314  TRP A CZ3 1 
ATOM   1668 C  CH2 . TRP A 1 314 ? 149.040 128.367 176.925 1.00 69.25  ? 314  TRP A CH2 1 
ATOM   1669 N  N   . TRP A 1 315 ? 145.695 136.361 177.472 1.00 61.95  ? 315  TRP A N   1 
ATOM   1670 C  CA  . TRP A 1 315 ? 145.016 137.510 176.882 1.00 61.95  ? 315  TRP A CA  1 
ATOM   1671 C  C   . TRP A 1 315 ? 145.871 138.763 177.017 1.00 61.95  ? 315  TRP A C   1 
ATOM   1672 O  O   . TRP A 1 315 ? 146.065 139.507 176.048 1.00 61.95  ? 315  TRP A O   1 
ATOM   1673 C  CB  . TRP A 1 315 ? 143.648 137.712 177.532 1.00 61.95  ? 315  TRP A CB  1 
ATOM   1674 C  CG  . TRP A 1 315 ? 142.746 138.645 176.770 1.00 61.95  ? 315  TRP A CG  1 
ATOM   1675 C  CD1 . TRP A 1 315 ? 143.082 139.423 175.699 1.00 61.95  ? 315  TRP A CD1 1 
ATOM   1676 C  CD2 . TRP A 1 315 ? 141.356 138.891 177.021 1.00 61.95  ? 315  TRP A CD2 1 
ATOM   1677 N  NE1 . TRP A 1 315 ? 141.991 140.138 175.271 1.00 61.95  ? 315  TRP A NE1 1 
ATOM   1678 C  CE2 . TRP A 1 315 ? 140.919 139.829 176.066 1.00 61.95  ? 315  TRP A CE2 1 
ATOM   1679 C  CE3 . TRP A 1 315 ? 140.440 138.409 177.962 1.00 61.95  ? 315  TRP A CE3 1 
ATOM   1680 C  CZ2 . TRP A 1 315 ? 139.606 140.295 176.024 1.00 61.95  ? 315  TRP A CZ2 1 
ATOM   1681 C  CZ3 . TRP A 1 315 ? 139.138 138.873 177.918 1.00 61.95  ? 315  TRP A CZ3 1 
ATOM   1682 C  CH2 . TRP A 1 315 ? 138.733 139.806 176.956 1.00 61.95  ? 315  TRP A CH2 1 
ATOM   1683 N  N   . GLU A 1 316 ? 146.415 139.001 178.212 1.00 57.48  ? 316  GLU A N   1 
ATOM   1684 C  CA  . GLU A 1 316 ? 147.341 140.114 178.376 1.00 57.48  ? 316  GLU A CA  1 
ATOM   1685 C  C   . GLU A 1 316 ? 148.626 139.881 177.594 1.00 57.48  ? 316  GLU A C   1 
ATOM   1686 O  O   . GLU A 1 316 ? 149.274 140.840 177.171 1.00 57.48  ? 316  GLU A O   1 
ATOM   1687 C  CB  . GLU A 1 316 ? 147.642 140.337 179.857 1.00 57.48  ? 316  GLU A CB  1 
ATOM   1688 C  CG  . GLU A 1 316 ? 148.494 141.560 180.142 1.00 57.48  ? 316  GLU A CG  1 
ATOM   1689 C  CD  . GLU A 1 316 ? 148.993 141.600 181.570 1.00 57.48  ? 316  GLU A CD  1 
ATOM   1690 O  OE1 . GLU A 1 316 ? 149.674 140.642 181.990 1.00 57.48  ? 316  GLU A OE1 1 
ATOM   1691 O  OE2 . GLU A 1 316 ? 148.701 142.590 182.272 1.00 57.48  ? 316  GLU A OE2 1 
ATOM   1692 N  N   . ALA A 1 317 ? 149.000 138.620 177.375 1.00 55.01  ? 317  ALA A N   1 
ATOM   1693 C  CA  . ALA A 1 317 ? 150.155 138.333 176.531 1.00 55.01  ? 317  ALA A CA  1 
ATOM   1694 C  C   . ALA A 1 317 ? 149.910 138.764 175.090 1.00 55.01  ? 317  ALA A C   1 
ATOM   1695 O  O   . ALA A 1 317 ? 150.770 139.391 174.462 1.00 55.01  ? 317  ALA A O   1 
ATOM   1696 C  CB  . ALA A 1 317 ? 150.486 136.846 176.598 1.00 55.01  ? 317  ALA A CB  1 
ATOM   1697 N  N   . ALA A 1 318 ? 148.739 138.434 174.545 1.00 54.29  ? 318  ALA A N   1 
ATOM   1698 C  CA  . ALA A 1 318 ? 148.392 138.906 173.212 1.00 54.29  ? 318  ALA A CA  1 
ATOM   1699 C  C   . ALA A 1 318 ? 148.249 140.419 173.168 1.00 54.29  ? 318  ALA A C   1 
ATOM   1700 O  O   . ALA A 1 318 ? 148.553 141.031 172.140 1.00 54.29  ? 318  ALA A O   1 
ATOM   1701 C  CB  . ALA A 1 318 ? 147.102 138.242 172.734 1.00 54.29  ? 318  ALA A CB  1 
ATOM   1702 N  N   . LEU A 1 319 ? 147.797 141.037 174.258 1.00 47.26  ? 319  LEU A N   1 
ATOM   1703 C  CA  . LEU A 1 319 ? 147.782 142.491 174.322 1.00 47.26  ? 319  LEU A CA  1 
ATOM   1704 C  C   . LEU A 1 319 ? 149.187 143.079 174.310 1.00 47.26  ? 319  LEU A C   1 
ATOM   1705 O  O   . LEU A 1 319 ? 149.395 144.146 173.724 1.00 47.26  ? 319  LEU A O   1 
ATOM   1706 C  CB  . LEU A 1 319 ? 147.027 142.954 175.568 1.00 47.26  ? 319  LEU A CB  1 
ATOM   1707 C  CG  . LEU A 1 319 ? 146.261 144.265 175.404 1.00 47.26  ? 319  LEU A CG  1 
ATOM   1708 C  CD1 . LEU A 1 319 ? 145.403 144.211 174.155 1.00 47.26  ? 319  LEU A CD1 1 
ATOM   1709 C  CD2 . LEU A 1 319 ? 145.406 144.542 176.627 1.00 47.26  ? 319  LEU A CD2 1 
ATOM   1710 N  N   . PHE A 1 320 ? 150.146 142.409 174.952 1.00 43.52  ? 320  PHE A N   1 
ATOM   1711 C  CA  . PHE A 1 320 ? 151.550 142.792 174.830 1.00 43.52  ? 320  PHE A CA  1 
ATOM   1712 C  C   . PHE A 1 320 ? 152.027 142.652 173.393 1.00 43.52  ? 320  PHE A C   1 
ATOM   1713 O  O   . PHE A 1 320 ? 152.801 143.481 172.900 1.00 43.52  ? 320  PHE A O   1 
ATOM   1714 C  CB  . PHE A 1 320 ? 152.414 141.924 175.743 1.00 43.52  ? 320  PHE A CB  1 
ATOM   1715 C  CG  . PHE A 1 320 ? 152.718 142.544 177.070 1.00 43.52  ? 320  PHE A CG  1 
ATOM   1716 C  CD1 . PHE A 1 320 ? 151.739 142.655 178.036 1.00 43.52  ? 320  PHE A CD1 1 
ATOM   1717 C  CD2 . PHE A 1 320 ? 153.985 143.006 177.355 1.00 43.52  ? 320  PHE A CD2 1 
ATOM   1718 C  CE1 . PHE A 1 320 ? 152.018 143.217 179.260 1.00 43.52  ? 320  PHE A CE1 1 
ATOM   1719 C  CE2 . PHE A 1 320 ? 154.267 143.570 178.575 1.00 43.52  ? 320  PHE A CE2 1 
ATOM   1720 C  CZ  . PHE A 1 320 ? 153.282 143.677 179.527 1.00 43.52  ? 320  PHE A CZ  1 
ATOM   1721 N  N   . ALA A 1 321 ? 151.603 141.579 172.724 1.00 41.77  ? 321  ALA A N   1 
ATOM   1722 C  CA  . ALA A 1 321 ? 151.975 141.379 171.329 1.00 41.77  ? 321  ALA A CA  1 
ATOM   1723 C  C   . ALA A 1 321 ? 151.440 142.503 170.455 1.00 41.77  ? 321  ALA A C   1 
ATOM   1724 O  O   . ALA A 1 321 ? 152.136 142.994 169.560 1.00 41.77  ? 321  ALA A O   1 
ATOM   1725 C  CB  . ALA A 1 321 ? 151.466 140.026 170.837 1.00 41.77  ? 321  ALA A CB  1 
ATOM   1726 N  N   . LEU A 1 322 ? 150.202 142.925 170.701 1.00 38.89  ? 322  LEU A N   1 
ATOM   1727 C  CA  . LEU A 1 322 ? 149.656 144.063 169.972 1.00 38.89  ? 322  LEU A CA  1 
ATOM   1728 C  C   . LEU A 1 322 ? 150.468 145.321 170.245 1.00 38.89  ? 322  LEU A C   1 
ATOM   1729 O  O   . LEU A 1 322 ? 150.723 146.114 169.332 1.00 38.89  ? 322  LEU A O   1 
ATOM   1730 C  CB  . LEU A 1 322 ? 148.194 144.285 170.348 1.00 38.89  ? 322  LEU A CB  1 
ATOM   1731 C  CG  . LEU A 1 322 ? 147.501 145.419 169.592 1.00 38.89  ? 322  LEU A CG  1 
ATOM   1732 C  CD1 . LEU A 1 322 ? 147.782 145.319 168.104 1.00 38.89  ? 322  LEU A CD1 1 
ATOM   1733 C  CD2 . LEU A 1 322 ? 146.006 145.432 169.862 1.00 38.89  ? 322  LEU A CD2 1 
ATOM   1734 N  N   . SER A 1 323 ? 150.882 145.519 171.497 1.00 35.82  ? 323  SER A N   1 
ATOM   1735 C  CA  . SER A 1 323 ? 151.661 146.701 171.851 1.00 35.82  ? 323  SER A CA  1 
ATOM   1736 C  C   . SER A 1 323 ? 152.999 146.727 171.124 1.00 35.82  ? 323  SER A C   1 
ATOM   1737 O  O   . SER A 1 323 ? 153.411 147.767 170.604 1.00 35.82  ? 323  SER A O   1 
ATOM   1738 C  CB  . SER A 1 323 ? 151.876 146.752 173.361 1.00 35.82  ? 323  SER A CB  1 
ATOM   1739 O  OG  . SER A 1 323 ? 152.965 147.598 173.682 1.00 35.82  ? 323  SER A OG  1 
ATOM   1740 N  N   . VAL A 1 324 ? 153.699 145.592 171.086 1.00 35.73  ? 324  VAL A N   1 
ATOM   1741 C  CA  . VAL A 1 324 ? 154.990 145.572 170.400 1.00 35.73  ? 324  VAL A CA  1 
ATOM   1742 C  C   . VAL A 1 324 ? 154.804 145.700 168.893 1.00 35.73  ? 324  VAL A C   1 
ATOM   1743 O  O   . VAL A 1 324 ? 155.595 146.371 168.222 1.00 35.73  ? 324  VAL A O   1 
ATOM   1744 C  CB  . VAL A 1 324 ? 155.804 144.316 170.774 1.00 35.73  ? 324  VAL A CB  1 
ATOM   1745 C  CG1 . VAL A 1 324 ? 154.961 143.084 170.709 1.00 35.73  ? 324  VAL A CG1 1 
ATOM   1746 C  CG2 . VAL A 1 324 ? 156.985 144.154 169.852 1.00 35.73  ? 324  VAL A CG2 1 
ATOM   1747 N  N   . ALA A 1 325 ? 153.761 145.083 168.333 1.00 35.26  ? 325  ALA A N   1 
ATOM   1748 C  CA  . ALA A 1 325 ? 153.528 145.197 166.897 1.00 35.26  ? 325  ALA A CA  1 
ATOM   1749 C  C   . ALA A 1 325 ? 153.201 146.629 166.494 1.00 35.26  ? 325  ALA A C   1 
ATOM   1750 O  O   . ALA A 1 325 ? 153.660 147.103 165.450 1.00 35.26  ? 325  ALA A O   1 
ATOM   1751 C  CB  . ALA A 1 325 ? 152.408 144.251 166.470 1.00 35.26  ? 325  ALA A CB  1 
ATOM   1752 N  N   . VAL A 1 326 ? 152.401 147.333 167.301 1.00 32.66  ? 326  VAL A N   1 
ATOM   1753 C  CA  . VAL A 1 326 ? 152.062 148.722 167.001 1.00 32.66  ? 326  VAL A CA  1 
ATOM   1754 C  C   . VAL A 1 326 ? 153.158 149.685 167.432 1.00 32.66  ? 326  VAL A C   1 
ATOM   1755 O  O   . VAL A 1 326 ? 153.136 150.857 167.028 1.00 32.66  ? 326  VAL A O   1 
ATOM   1756 C  CB  . VAL A 1 326 ? 150.724 149.112 167.662 1.00 32.66  ? 326  VAL A CB  1 
ATOM   1757 C  CG1 . VAL A 1 326 ? 150.914 149.351 169.138 1.00 32.66  ? 326  VAL A CG1 1 
ATOM   1758 C  CG2 . VAL A 1 326 ? 150.119 150.329 166.992 1.00 32.66  ? 326  VAL A CG2 1 
ATOM   1759 N  N   . GLY A 1 327 ? 154.122 149.229 168.230 1.00 31.27  ? 327  GLY A N   1 
ATOM   1760 C  CA  . GLY A 1 327 ? 155.184 150.116 168.667 1.00 31.27  ? 327  GLY A CA  1 
ATOM   1761 C  C   . GLY A 1 327 ? 156.051 150.598 167.524 1.00 31.27  ? 327  GLY A C   1 
ATOM   1762 O  O   . GLY A 1 327 ? 156.392 151.779 167.450 1.00 31.27  ? 327  GLY A O   1 
ATOM   1763 N  N   . LEU A 1 328 ? 156.419 149.695 166.616 1.00 32.25  ? 328  LEU A N   1 
ATOM   1764 C  CA  . LEU A 1 328 ? 157.234 150.040 165.453 1.00 32.25  ? 328  LEU A CA  1 
ATOM   1765 C  C   . LEU A 1 328 ? 156.373 149.874 164.203 1.00 32.25  ? 328  LEU A C   1 
ATOM   1766 O  O   . LEU A 1 328 ? 156.384 148.842 163.531 1.00 32.25  ? 328  LEU A O   1 
ATOM   1767 C  CB  . LEU A 1 328 ? 158.569 149.184 165.408 1.00 32.25  ? 328  LEU A CB  1 
ATOM   1768 C  CG  . LEU A 1 328 ? 158.689 147.718 164.983 1.00 32.25  ? 328  LEU A CG  1 
ATOM   1769 C  CD1 . LEU A 1 328 ? 160.144 147.306 164.956 1.00 32.25  ? 328  LEU A CD1 1 
ATOM   1770 C  CD2 . LEU A 1 328 ? 157.909 146.813 165.903 1.00 32.25  ? 328  LEU A CD2 1 
ATOM   1771 N  N   . THR A 1 329 ? 155.604 150.913 163.906 1.00 38.03  ? 329  THR A N   1 
ATOM   1772 C  CA  . THR A 1 329 ? 154.833 151.041 162.679 1.00 38.03  ? 329  THR A CA  1 
ATOM   1773 C  C   . THR A 1 329 ? 154.446 152.507 162.487 1.00 38.03  ? 329  THR A C   1 
ATOM   1774 O  O   . THR A 1 329 ? 153.399 152.958 162.966 1.00 38.03  ? 329  THR A O   1 
ATOM   1775 C  CB  . THR A 1 329 ? 153.632 150.078 162.684 1.00 38.03  ? 329  THR A CB  1 
ATOM   1776 O  OG1 . THR A 1 329 ? 152.993 150.078 161.400 1.00 38.03  ? 329  THR A OG1 1 
ATOM   1777 C  CG2 . THR A 1 329 ? 152.630 150.349 163.808 1.00 38.03  ? 329  THR A CG2 1 
ATOM   1778 N  N   . PRO A 1 330 ? 155.288 153.294 161.823 1.00 37.75  ? 330  PRO A N   1 
ATOM   1779 C  CA  . PRO A 1 330 ? 154.987 154.721 161.664 1.00 37.75  ? 330  PRO A CA  1 
ATOM   1780 C  C   . PRO A 1 330 ? 153.700 154.915 160.879 1.00 37.75  ? 330  PRO A C   1 
ATOM   1781 O  O   . PRO A 1 330 ? 153.568 154.456 159.743 1.00 37.75  ? 330  PRO A O   1 
ATOM   1782 C  CB  . PRO A 1 330 ? 156.204 155.263 160.906 1.00 37.75  ? 330  PRO A CB  1 
ATOM   1783 C  CG  . PRO A 1 330 ? 157.247 154.196 161.003 1.00 37.75  ? 330  PRO A CG  1 
ATOM   1784 C  CD  . PRO A 1 330 ? 156.523 152.906 161.130 1.00 37.75  ? 330  PRO A CD  1 
ATOM   1785 N  N   . GLU A 1 331 ? 152.738 155.592 161.507 1.00 41.66  ? 331  GLU A N   1 
ATOM   1786 C  CA  . GLU A 1 331 ? 151.421 155.736 160.900 1.00 41.66  ? 331  GLU A CA  1 
ATOM   1787 C  C   . GLU A 1 331 ? 151.483 156.567 159.627 1.00 41.66  ? 331  GLU A C   1 
ATOM   1788 O  O   . GLU A 1 331 ? 150.978 156.146 158.580 1.00 41.66  ? 331  GLU A O   1 
ATOM   1789 C  CB  . GLU A 1 331 ? 150.454 156.366 161.899 1.00 41.66  ? 331  GLU A CB  1 
ATOM   1790 C  CG  . GLU A 1 331 ? 150.524 155.762 163.284 1.00 41.66  ? 331  GLU A CG  1 
ATOM   1791 C  CD  . GLU A 1 331 ? 150.324 154.262 163.283 1.00 41.66  ? 331  GLU A CD  1 
ATOM   1792 O  OE1 . GLU A 1 331 ? 149.567 153.760 162.427 1.00 41.66  ? 331  GLU A OE1 1 
ATOM   1793 O  OE2 . GLU A 1 331 ? 150.923 153.584 164.143 1.00 41.66  ? 331  GLU A OE2 1 
ATOM   1794 N  N   . MET A 1 332 ? 152.103 157.742 159.691 1.00 37.55  ? 332  MET A N   1 
ATOM   1795 C  CA  . MET A 1 332 ? 152.168 158.639 158.549 1.00 37.55  ? 332  MET A CA  1 
ATOM   1796 C  C   . MET A 1 332 ? 153.482 158.529 157.792 1.00 37.55  ? 332  MET A C   1 
ATOM   1797 O  O   . MET A 1 332 ? 153.971 159.534 157.269 1.00 37.55  ? 332  MET A O   1 
ATOM   1798 C  CB  . MET A 1 332 ? 151.925 160.082 158.991 1.00 37.55  ? 332  MET A CB  1 
ATOM   1799 C  CG  . MET A 1 332 ? 150.930 160.223 160.126 1.00 37.55  ? 332  MET A CG  1 
ATOM   1800 S  SD  . MET A 1 332 ? 150.117 161.835 160.147 1.00 37.55  ? 332  MET A SD  1 
ATOM   1801 C  CE  . MET A 1 332 ? 151.361 162.851 160.932 1.00 37.55  ? 332  MET A CE  1 
ATOM   1802 N  N   . LEU A 1 333 ? 154.067 157.334 157.724 1.00 34.56  ? 333  LEU A N   1 
ATOM   1803 C  CA  . LEU A 1 333 ? 155.270 157.162 156.913 1.00 34.56  ? 333  LEU A CA  1 
ATOM   1804 C  C   . LEU A 1 333 ? 155.023 157.500 155.449 1.00 34.56  ? 333  LEU A C   1 
ATOM   1805 O  O   . LEU A 1 333 ? 155.772 158.325 154.897 1.00 34.56  ? 333  LEU A O   1 
ATOM   1806 C  CB  . LEU A 1 333 ? 155.813 155.739 157.086 1.00 34.56  ? 333  LEU A CB  1 
ATOM   1807 C  CG  . LEU A 1 333 ? 156.823 155.230 156.057 1.00 34.56  ? 333  LEU A CG  1 
ATOM   1808 C  CD1 . LEU A 1 333 ? 158.087 156.061 156.086 1.00 34.56  ? 333  LEU A CD1 1 
ATOM   1809 C  CD2 . LEU A 1 333 ? 157.140 153.766 156.293 1.00 34.56  ? 333  LEU A CD2 1 
ATOM   1810 N  N   . PRO A 1 334 ? 154.015 156.938 154.767 1.00 37.94  ? 334  PRO A N   1 
ATOM   1811 C  CA  . PRO A 1 334 ? 153.765 157.380 153.388 1.00 37.94  ? 334  PRO A CA  1 
ATOM   1812 C  C   . PRO A 1 334 ? 153.429 158.852 153.293 1.00 37.94  ? 334  PRO A C   1 
ATOM   1813 O  O   . PRO A 1 334 ? 153.866 159.519 152.351 1.00 37.94  ? 334  PRO A O   1 
ATOM   1814 C  CB  . PRO A 1 334 ? 152.592 156.497 152.944 1.00 37.94  ? 334  PRO A CB  1 
ATOM   1815 C  CG  . PRO A 1 334 ? 152.653 155.320 153.831 1.00 37.94  ? 334  PRO A CG  1 
ATOM   1816 C  CD  . PRO A 1 334 ? 153.082 155.866 155.151 1.00 37.94  ? 334  PRO A CD  1 
ATOM   1817 N  N   . MET A 1 335 ? 152.681 159.387 154.260 1.00 38.74  ? 335  MET A N   1 
ATOM   1818 C  CA  . MET A 1 335 ? 152.322 160.799 154.213 1.00 38.74  ? 335  MET A CA  1 
ATOM   1819 C  C   . MET A 1 335 ? 153.556 161.686 154.300 1.00 38.74  ? 335  MET A C   1 
ATOM   1820 O  O   . MET A 1 335 ? 153.723 162.606 153.494 1.00 38.74  ? 335  MET A O   1 
ATOM   1821 C  CB  . MET A 1 335 ? 151.336 161.128 155.332 1.00 38.74  ? 335  MET A CB  1 
ATOM   1822 C  CG  . MET A 1 335 ? 149.884 160.958 154.932 1.00 38.74  ? 335  MET A CG  1 
ATOM   1823 S  SD  . MET A 1 335 ? 149.400 159.234 154.743 1.00 38.74  ? 335  MET A SD  1 
ATOM   1824 C  CE  . MET A 1 335 ? 149.249 158.724 156.450 1.00 38.74  ? 335  MET A CE  1 
ATOM   1825 N  N   . ILE A 1 336 ? 154.447 161.408 155.253 1.00 31.38  ? 336  ILE A N   1 
ATOM   1826 C  CA  . ILE A 1 336 ? 155.660 162.207 155.384 1.00 31.38  ? 336  ILE A CA  1 
ATOM   1827 C  C   . ILE A 1 336 ? 156.586 162.048 154.188 1.00 31.38  ? 336  ILE A C   1 
ATOM   1828 O  O   . ILE A 1 336 ? 157.135 163.045 153.701 1.00 31.38  ? 336  ILE A O   1 
ATOM   1829 C  CB  . ILE A 1 336 ? 156.422 161.849 156.668 1.00 31.38  ? 336  ILE A CB  1 
ATOM   1830 C  CG1 . ILE A 1 336 ? 155.559 162.143 157.888 1.00 31.38  ? 336  ILE A CG1 1 
ATOM   1831 C  CG2 . ILE A 1 336 ? 157.714 162.638 156.756 1.00 31.38  ? 336  ILE A CG2 1 
ATOM   1832 C  CD1 . ILE A 1 336 ? 155.326 163.593 158.105 1.00 31.38  ? 336  ILE A CD1 1 
ATOM   1833 N  N   . VAL A 1 337 ? 156.780 160.824 153.698 1.00 31.71  ? 337  VAL A N   1 
ATOM   1834 C  CA  . VAL A 1 337 ? 157.673 160.626 152.563 1.00 31.71  ? 337  VAL A CA  1 
ATOM   1835 C  C   . VAL A 1 337 ? 157.135 161.322 151.315 1.00 31.71  ? 337  VAL A C   1 
ATOM   1836 O  O   . VAL A 1 337 ? 157.883 161.993 150.590 1.00 31.71  ? 337  VAL A O   1 
ATOM   1837 C  CB  . VAL A 1 337 ? 157.895 159.122 152.338 1.00 31.71  ? 337  VAL A CB  1 
ATOM   1838 C  CG1 . VAL A 1 337 ? 158.710 158.896 151.105 1.00 31.71  ? 337  VAL A CG1 1 
ATOM   1839 C  CG2 . VAL A 1 337 ? 158.599 158.519 153.532 1.00 31.71  ? 337  VAL A CG2 1 
ATOM   1840 N  N   . THR A 1 338 ? 155.832 161.190 151.050 1.00 34.12  ? 338  THR A N   1 
ATOM   1841 C  CA  . THR A 1 338 ? 155.246 161.852 149.892 1.00 34.12  ? 338  THR A CA  1 
ATOM   1842 C  C   . THR A 1 338 ? 155.272 163.364 150.050 1.00 34.12  ? 338  THR A C   1 
ATOM   1843 O  O   . THR A 1 338 ? 155.464 164.086 149.069 1.00 34.12  ? 338  THR A O   1 
ATOM   1844 C  CB  . THR A 1 338 ? 153.819 161.358 149.669 1.00 34.12  ? 338  THR A CB  1 
ATOM   1845 O  OG1 . THR A 1 338 ? 153.819 159.929 149.582 1.00 34.12  ? 338  THR A OG1 1 
ATOM   1846 C  CG2 . THR A 1 338 ? 153.260 161.924 148.380 1.00 34.12  ? 338  THR A CG2 1 
ATOM   1847 N  N   . SER A 1 339 ? 155.092 163.869 151.271 1.00 30.69  ? 339  SER A N   1 
ATOM   1848 C  CA  . SER A 1 339 ? 155.217 165.305 151.488 1.00 30.69  ? 339  SER A CA  1 
ATOM   1849 C  C   . SER A 1 339 ? 156.631 165.784 151.193 1.00 30.69  ? 339  SER A C   1 
ATOM   1850 O  O   . SER A 1 339 ? 156.820 166.849 150.594 1.00 30.69  ? 339  SER A O   1 
ATOM   1851 C  CB  . SER A 1 339 ? 154.821 165.658 152.920 1.00 30.69  ? 339  SER A CB  1 
ATOM   1852 O  OG  . SER A 1 339 ? 155.132 167.008 153.212 1.00 30.69  ? 339  SER A OG  1 
ATOM   1853 N  N   . THR A 1 340 ? 157.637 165.013 151.608 1.00 29.66  ? 340  THR A N   1 
ATOM   1854 C  CA  . THR A 1 340 ? 159.021 165.383 151.325 1.00 29.66  ? 340  THR A CA  1 
ATOM   1855 C  C   . THR A 1 340 ? 159.279 165.434 149.826 1.00 29.66  ? 340  THR A C   1 
ATOM   1856 O  O   . THR A 1 340 ? 159.845 166.407 149.308 1.00 29.66  ? 340  THR A O   1 
ATOM   1857 C  CB  . THR A 1 340 ? 159.976 164.396 151.991 1.00 29.66  ? 340  THR A CB  1 
ATOM   1858 O  OG1 . THR A 1 340 ? 159.765 164.406 153.407 1.00 29.66  ? 340  THR A OG1 1 
ATOM   1859 C  CG2 . THR A 1 340 ? 161.409 164.777 151.700 1.00 29.66  ? 340  THR A CG2 1 
ATOM   1860 N  N   . LEU A 1 341 ? 158.856 164.393 149.107 1.00 32.48  ? 341  LEU A N   1 
ATOM   1861 C  CA  . LEU A 1 341 ? 159.074 164.367 147.664 1.00 32.48  ? 341  LEU A CA  1 
ATOM   1862 C  C   . LEU A 1 341 ? 158.305 165.487 146.970 1.00 32.48  ? 341  LEU A C   1 
ATOM   1863 O  O   . LEU A 1 341 ? 158.804 166.098 146.019 1.00 32.48  ? 341  LEU A O   1 
ATOM   1864 C  CB  . LEU A 1 341 ? 158.681 163.006 147.098 1.00 32.48  ? 341  LEU A CB  1 
ATOM   1865 C  CG  . LEU A 1 341 ? 159.660 161.866 147.361 1.00 32.48  ? 341  LEU A CG  1 
ATOM   1866 C  CD1 . LEU A 1 341 ? 159.477 160.784 146.325 1.00 32.48  ? 341  LEU A CD1 1 
ATOM   1867 C  CD2 . LEU A 1 341 ? 161.087 162.368 147.355 1.00 32.48  ? 341  LEU A CD2 1 
ATOM   1868 N  N   . ALA A 1 342 ? 157.085 165.770 147.431 1.00 31.80  ? 342  ALA A N   1 
ATOM   1869 C  CA  . ALA A 1 342 ? 156.293 166.837 146.833 1.00 31.80  ? 342  ALA A CA  1 
ATOM   1870 C  C   . ALA A 1 342 ? 156.936 168.197 147.056 1.00 31.80  ? 342  ALA A C   1 
ATOM   1871 O  O   . ALA A 1 342 ? 156.945 169.042 146.155 1.00 31.80  ? 342  ALA A O   1 
ATOM   1872 C  CB  . ALA A 1 342 ? 154.875 166.816 147.399 1.00 31.80  ? 342  ALA A CB  1 
ATOM   1873 N  N   . ARG A 1 343 ? 157.467 168.437 148.253 1.00 29.36  ? 343  ARG A N   1 
ATOM   1874 C  CA  . ARG A 1 343 ? 158.152 169.701 148.487 1.00 29.36  ? 343  ARG A CA  1 
ATOM   1875 C  C   . ARG A 1 343 ? 159.398 169.805 147.625 1.00 29.36  ? 343  ARG A C   1 
ATOM   1876 O  O   . ARG A 1 343 ? 159.731 170.888 147.132 1.00 29.36  ? 343  ARG A O   1 
ATOM   1877 C  CB  . ARG A 1 343 ? 158.508 169.859 149.961 1.00 29.36  ? 343  ARG A CB  1 
ATOM   1878 C  CG  . ARG A 1 343 ? 158.956 171.265 150.315 1.00 29.36  ? 343  ARG A CG  1 
ATOM   1879 C  CD  . ARG A 1 343 ? 160.468 171.424 150.275 1.00 29.36  ? 343  ARG A CD  1 
ATOM   1880 N  NE  . ARG A 1 343 ? 160.908 172.657 150.915 1.00 29.36  ? 343  ARG A NE  1 
ATOM   1881 C  CZ  . ARG A 1 343 ? 160.588 173.878 150.506 1.00 29.36  ? 343  ARG A CZ  1 
ATOM   1882 N  NH1 . ARG A 1 343 ? 159.862 174.078 149.419 1.00 29.36  ? 343  ARG A NH1 1 
ATOM   1883 N  NH2 . ARG A 1 343 ? 161.018 174.927 151.200 1.00 29.36  ? 343  ARG A NH2 1 
ATOM   1884 N  N   . GLY A 1 344 ? 160.113 168.694 147.449 1.00 30.05  ? 344  GLY A N   1 
ATOM   1885 C  CA  . GLY A 1 344 ? 161.246 168.709 146.538 1.00 30.05  ? 344  GLY A CA  1 
ATOM   1886 C  C   . GLY A 1 344 ? 160.836 169.080 145.127 1.00 30.05  ? 344  GLY A C   1 
ATOM   1887 O  O   . GLY A 1 344 ? 161.480 169.902 144.472 1.00 30.05  ? 344  GLY A O   1 
ATOM   1888 N  N   . ALA A 1 345 ? 159.740 168.489 144.648 1.00 30.16  ? 345  ALA A N   1 
ATOM   1889 C  CA  . ALA A 1 345 ? 159.244 168.795 143.312 1.00 30.16  ? 345  ALA A CA  1 
ATOM   1890 C  C   . ALA A 1 345 ? 158.800 170.242 143.182 1.00 30.16  ? 345  ALA A C   1 
ATOM   1891 O  O   . ALA A 1 345 ? 158.992 170.846 142.122 1.00 30.16  ? 345  ALA A O   1 
ATOM   1892 C  CB  . ALA A 1 345 ? 158.084 167.867 142.954 1.00 30.16  ? 345  ALA A CB  1 
ATOM   1893 N  N   . VAL A 1 346 ? 158.201 170.809 144.230 1.00 31.68  ? 346  VAL A N   1 
ATOM   1894 C  CA  . VAL A 1 346 ? 157.774 172.201 144.209 1.00 31.68  ? 346  VAL A CA  1 
ATOM   1895 C  C   . VAL A 1 346 ? 158.946 173.166 144.229 1.00 31.68  ? 346  VAL A C   1 
ATOM   1896 O  O   . VAL A 1 346 ? 158.940 174.146 143.473 1.00 31.68  ? 346  VAL A O   1 
ATOM   1897 C  CB  . VAL A 1 346 ? 156.814 172.503 145.375 1.00 31.68  ? 346  VAL A CB  1 
ATOM   1898 C  CG1 . VAL A 1 346 ? 156.723 173.997 145.623 1.00 31.68  ? 346  VAL A CG1 1 
ATOM   1899 C  CG2 . VAL A 1 346 ? 155.441 171.929 145.082 1.00 31.68  ? 346  VAL A CG2 1 
ATOM   1900 N  N   . LYS A 1 347 ? 159.966 172.915 145.052 1.00 32.39  ? 347  LYS A N   1 
ATOM   1901 C  CA  . LYS A 1 347 ? 161.127 173.790 145.077 1.00 32.39  ? 347  LYS A CA  1 
ATOM   1902 C  C   . LYS A 1 347 ? 162.069 173.578 143.903 1.00 32.39  ? 347  LYS A C   1 
ATOM   1903 O  O   . LYS A 1 347 ? 162.912 174.442 143.648 1.00 32.39  ? 347  LYS A O   1 
ATOM   1904 C  CB  . LYS A 1 347 ? 161.914 173.625 146.383 1.00 32.39  ? 347  LYS A CB  1 
ATOM   1905 C  CG  . LYS A 1 347 ? 162.719 174.865 146.741 1.00 32.39  ? 347  LYS A CG  1 
ATOM   1906 C  CD  . LYS A 1 347 ? 164.140 174.531 147.137 1.00 32.39  ? 347  LYS A CD  1 
ATOM   1907 C  CE  . LYS A 1 347 ? 164.166 173.577 148.310 1.00 32.39  ? 347  LYS A CE  1 
ATOM   1908 N  NZ  . LYS A 1 347 ? 165.531 173.044 148.555 1.00 32.39  ? 347  LYS A NZ  1 
ATOM   1909 N  N   . LEU A 1 348 ? 161.951 172.460 143.186 1.00 34.72  ? 348  LEU A N   1 
ATOM   1910 C  CA  . LEU A 1 348 ? 162.678 172.321 141.930 1.00 34.72  ? 348  LEU A CA  1 
ATOM   1911 C  C   . LEU A 1 348 ? 162.035 173.159 140.836 1.00 34.72  ? 348  LEU A C   1 
ATOM   1912 O  O   . LEU A 1 348 ? 162.711 173.584 139.893 1.00 34.72  ? 348  LEU A O   1 
ATOM   1913 C  CB  . LEU A 1 348 ? 162.735 170.853 141.515 1.00 34.72  ? 348  LEU A CB  1 
ATOM   1914 C  CG  . LEU A 1 348 ? 163.897 170.043 142.082 1.00 34.72  ? 348  LEU A CG  1 
ATOM   1915 C  CD1 . LEU A 1 348 ? 164.022 168.710 141.374 1.00 34.72  ? 348  LEU A CD1 1 
ATOM   1916 C  CD2 . LEU A 1 348 ? 165.175 170.836 141.953 1.00 34.72  ? 348  LEU A CD2 1 
ATOM   1917 N  N   . SER A 1 349 ? 160.729 173.408 140.945 1.00 35.86  ? 349  SER A N   1 
ATOM   1918 C  CA  . SER A 1 349 ? 160.031 174.178 139.922 1.00 35.86  ? 349  SER A CA  1 
ATOM   1919 C  C   . SER A 1 349 ? 160.539 175.610 139.849 1.00 35.86  ? 349  SER A C   1 
ATOM   1920 O  O   . SER A 1 349 ? 160.427 176.253 138.800 1.00 35.86  ? 349  SER A O   1 
ATOM   1921 C  CB  . SER A 1 349 ? 158.528 174.162 140.189 1.00 35.86  ? 349  SER A CB  1 
ATOM   1922 O  OG  . SER A 1 349 ? 157.835 174.942 139.233 1.00 35.86  ? 349  SER A OG  1 
ATOM   1923 N  N   . LYS A 1 350 ? 161.089 176.130 140.942 1.00 36.18  ? 350  LYS A N   1 
ATOM   1924 C  CA  . LYS A 1 350 ? 161.663 177.467 140.941 1.00 36.18  ? 350  LYS A CA  1 
ATOM   1925 C  C   . LYS A 1 350 ? 163.110 177.491 140.472 1.00 36.18  ? 350  LYS A C   1 
ATOM   1926 O  O   . LYS A 1 350 ? 163.666 178.577 140.284 1.00 36.18  ? 350  LYS A O   1 
ATOM   1927 C  CB  . LYS A 1 350 ? 161.568 178.084 142.339 1.00 36.18  ? 350  LYS A CB  1 
ATOM   1928 C  CG  . LYS A 1 350 ? 160.190 177.979 142.966 1.00 36.18  ? 350  LYS A CG  1 
ATOM   1929 C  CD  . LYS A 1 350 ? 160.243 178.227 144.463 1.00 36.18  ? 350  LYS A CD  1 
ATOM   1930 C  CE  . LYS A 1 350 ? 158.854 178.459 145.030 1.00 36.18  ? 350  LYS A CE  1 
ATOM   1931 N  NZ  . LYS A 1 350 ? 157.798 177.865 144.165 1.00 36.18  ? 350  LYS A NZ  1 
ATOM   1932 N  N   . GLN A 1 351 ? 163.726 176.327 140.274 1.00 39.70  ? 351  GLN A N   1 
ATOM   1933 C  CA  . GLN A 1 351 ? 165.111 176.223 139.835 1.00 39.70  ? 351  GLN A CA  1 
ATOM   1934 C  C   . GLN A 1 351 ? 165.203 175.844 138.361 1.00 39.70  ? 351  GLN A C   1 
ATOM   1935 O  O   . GLN A 1 351 ? 166.205 175.278 137.921 1.00 39.70  ? 351  GLN A O   1 
ATOM   1936 C  CB  . GLN A 1 351 ? 165.865 175.209 140.692 1.00 39.70  ? 351  GLN A CB  1 
ATOM   1937 C  CG  . GLN A 1 351 ? 166.036 175.626 142.143 1.00 39.70  ? 351  GLN A CG  1 
ATOM   1938 C  CD  . GLN A 1 351 ? 167.335 175.135 142.743 1.00 39.70  ? 351  GLN A CD  1 
ATOM   1939 O  OE1 . GLN A 1 351 ? 167.671 173.956 142.644 1.00 39.70  ? 351  GLN A OE1 1 
ATOM   1940 N  NE2 . GLN A 1 351 ? 168.070 176.037 143.380 1.00 39.70  ? 351  GLN A NE2 1 
ATOM   1941 N  N   . LYS A 1 352 ? 164.153 176.144 137.596 1.00 42.93  ? 352  LYS A N   1 
ATOM   1942 C  CA  . LYS A 1 352 ? 164.058 175.839 136.170 1.00 42.93  ? 352  LYS A CA  1 
ATOM   1943 C  C   . LYS A 1 352 ? 164.096 174.343 135.891 1.00 42.93  ? 352  LYS A C   1 
ATOM   1944 O  O   . LYS A 1 352 ? 164.454 173.927 134.788 1.00 42.93  ? 352  LYS A O   1 
ATOM   1945 C  CB  . LYS A 1 352 ? 165.154 176.548 135.367 1.00 42.93  ? 352  LYS A CB  1 
ATOM   1946 C  CG  . LYS A 1 352 ? 165.070 178.062 135.399 1.00 42.93  ? 352  LYS A CG  1 
ATOM   1947 C  CD  . LYS A 1 352 ? 166.439 178.687 135.198 1.00 42.93  ? 352  LYS A CD  1 
ATOM   1948 C  CE  . LYS A 1 352 ? 166.502 180.087 135.776 1.00 42.93  ? 352  LYS A CE  1 
ATOM   1949 N  NZ  . LYS A 1 352 ? 167.243 180.109 137.065 1.00 42.93  ? 352  LYS A NZ  1 
ATOM   1950 N  N   . VAL A 1 353 ? 163.730 173.521 136.864 1.00 40.95  ? 353  VAL A N   1 
ATOM   1951 C  CA  . VAL A 1 353 ? 163.688 172.069 136.700 1.00 40.95  ? 353  VAL A CA  1 
ATOM   1952 C  C   . VAL A 1 353 ? 162.250 171.642 136.974 1.00 40.95  ? 353  VAL A C   1 
ATOM   1953 O  O   . VAL A 1 353 ? 161.860 171.401 138.119 1.00 40.95  ? 353  VAL A O   1 
ATOM   1954 C  CB  . VAL A 1 353 ? 164.672 171.347 137.623 1.00 40.95  ? 353  VAL A CB  1 
ATOM   1955 C  CG1 . VAL A 1 353 ? 164.994 169.978 137.082 1.00 40.95  ? 353  VAL A CG1 1 
ATOM   1956 C  CG2 . VAL A 1 353 ? 165.941 172.151 137.780 1.00 40.95  ? 353  VAL A CG2 1 
ATOM   1957 N  N   . ILE A 1 354 ? 161.448 171.541 135.917 1.00 42.52  ? 354  ILE A N   1 
ATOM   1958 C  CA  . ILE A 1 354 ? 160.048 171.132 136.034 1.00 42.52  ? 354  ILE A CA  1 
ATOM   1959 C  C   . ILE A 1 354 ? 160.016 169.609 135.989 1.00 42.52  ? 354  ILE A C   1 
ATOM   1960 O  O   . ILE A 1 354 ? 160.176 169.005 134.929 1.00 42.52  ? 354  ILE A O   1 
ATOM   1961 C  CB  . ILE A 1 354 ? 159.172 171.744 134.938 1.00 42.52  ? 354  ILE A CB  1 
ATOM   1962 C  CG1 . ILE A 1 354 ? 159.335 173.268 134.841 1.00 42.52  ? 354  ILE A CG1 1 
ATOM   1963 C  CG2 . ILE A 1 354 ? 157.717 171.378 135.160 1.00 42.52  ? 354  ILE A CG2 1 
ATOM   1964 C  CD1 . ILE A 1 354 ? 159.674 173.983 136.138 1.00 42.52  ? 354  ILE A CD1 1 
ATOM   1965 N  N   . VAL A 1 355 ? 159.808 168.982 137.137 1.00 48.37  ? 355  VAL A N   1 
ATOM   1966 C  CA  . VAL A 1 355 ? 159.822 167.527 137.219 1.00 48.37  ? 355  VAL A CA  1 
ATOM   1967 C  C   . VAL A 1 355 ? 158.414 166.991 136.999 1.00 48.37  ? 355  VAL A C   1 
ATOM   1968 O  O   . VAL A 1 355 ? 157.450 167.445 137.626 1.00 48.37  ? 355  VAL A O   1 
ATOM   1969 C  CB  . VAL A 1 355 ? 160.410 167.073 138.566 1.00 48.37  ? 355  VAL A CB  1 
ATOM   1970 C  CG1 . VAL A 1 355 ? 159.662 167.706 139.720 1.00 48.37  ? 355  VAL A CG1 1 
ATOM   1971 C  CG2 . VAL A 1 355 ? 160.388 165.566 138.670 1.00 48.37  ? 355  VAL A CG2 1 
ATOM   1972 N  N   . LYS A 1 356 ? 158.288 166.030 136.084 1.00 55.07  ? 356  LYS A N   1 
ATOM   1973 C  CA  . LYS A 1 356 ? 156.984 165.491 135.717 1.00 55.07  ? 356  LYS A CA  1 
ATOM   1974 C  C   . LYS A 1 356 ? 156.377 164.595 136.784 1.00 55.07  ? 356  LYS A C   1 
ATOM   1975 O  O   . LYS A 1 356 ? 155.182 164.716 137.073 1.00 55.07  ? 356  LYS A O   1 
ATOM   1976 C  CB  . LYS A 1 356 ? 157.080 164.698 134.412 1.00 55.07  ? 356  LYS A CB  1 
ATOM   1977 C  CG  . LYS A 1 356 ? 156.877 165.523 133.155 1.00 55.07  ? 356  LYS A CG  1 
ATOM   1978 C  CD  . LYS A 1 356 ? 157.070 164.683 131.897 1.00 55.07  ? 356  LYS A CD  1 
ATOM   1979 C  CE  . LYS A 1 356 ? 156.797 163.207 132.141 1.00 55.07  ? 356  LYS A CE  1 
ATOM   1980 N  NZ  . LYS A 1 356 ? 156.524 162.479 130.873 1.00 55.07  ? 356  LYS A NZ  1 
ATOM   1981 N  N   . HIS A 1 357 ? 157.161 163.699 137.375 1.00 59.72  ? 357  HIS A N   1 
ATOM   1982 C  CA  . HIS A 1 357 ? 156.636 162.696 138.288 1.00 59.72  ? 357  HIS A CA  1 
ATOM   1983 C  C   . HIS A 1 357 ? 157.363 162.764 139.620 1.00 59.72  ? 357  HIS A C   1 
ATOM   1984 O  O   . HIS A 1 357 ? 158.526 163.167 139.685 1.00 59.72  ? 357  HIS A O   1 
ATOM   1985 C  CB  . HIS A 1 357 ? 156.764 161.291 137.701 1.00 59.72  ? 357  HIS A CB  1 
ATOM   1986 C  CG  . HIS A 1 357 ? 155.811 160.305 138.298 1.00 59.72  ? 357  HIS A CG  1 
ATOM   1987 N  ND1 . HIS A 1 357 ? 154.670 160.688 138.969 1.00 59.72  ? 357  HIS A ND1 1 
ATOM   1988 C  CD2 . HIS A 1 357 ? 155.829 158.951 138.329 1.00 59.72  ? 357  HIS A CD2 1 
ATOM   1989 C  CE1 . HIS A 1 357 ? 154.026 159.613 139.387 1.00 59.72  ? 357  HIS A CE1 1 
ATOM   1990 N  NE2 . HIS A 1 357 ? 154.708 158.547 139.011 1.00 59.72  ? 357  HIS A NE2 1 
ATOM   1991 N  N   . LEU A 1 358 ? 156.662 162.367 140.682 1.00 51.29  ? 358  LEU A N   1 
ATOM   1992 C  CA  . LEU A 1 358 ? 157.246 162.384 142.019 1.00 51.29  ? 358  LEU A CA  1 
ATOM   1993 C  C   . LEU A 1 358 ? 158.430 161.430 142.109 1.00 51.29  ? 358  LEU A C   1 
ATOM   1994 O  O   . LEU A 1 358 ? 159.450 161.738 142.734 1.00 51.29  ? 358  LEU A O   1 
ATOM   1995 C  CB  . LEU A 1 358 ? 156.182 162.011 143.049 1.00 51.29  ? 358  LEU A CB  1 
ATOM   1996 C  CG  . LEU A 1 358 ? 155.419 163.162 143.701 1.00 51.29  ? 358  LEU A CG  1 
ATOM   1997 C  CD1 . LEU A 1 358 ? 154.180 162.641 144.405 1.00 51.29  ? 358  LEU A CD1 1 
ATOM   1998 C  CD2 . LEU A 1 358 ? 156.302 163.919 144.657 1.00 51.29  ? 358  LEU A CD2 1 
ATOM   1999 N  N   . ASP A 1 359 ? 158.301 160.257 141.487 1.00 53.00  ? 359  ASP A N   1 
ATOM   2000 C  CA  . ASP A 1 359 ? 159.352 159.248 141.549 1.00 53.00  ? 359  ASP A CA  1 
ATOM   2001 C  C   . ASP A 1 359 ? 160.639 159.738 140.899 1.00 53.00  ? 359  ASP A C   1 
ATOM   2002 O  O   . ASP A 1 359 ? 161.736 159.315 141.280 1.00 53.00  ? 359  ASP A O   1 
ATOM   2003 C  CB  . ASP A 1 359 ? 158.863 157.964 140.876 1.00 53.00  ? 359  ASP A CB  1 
ATOM   2004 C  CG  . ASP A 1 359 ? 159.992 157.030 140.500 1.00 53.00  ? 359  ASP A CG  1 
ATOM   2005 O  OD1 . ASP A 1 359 ? 160.846 156.743 141.365 1.00 53.00  ? 359  ASP A OD1 1 
ATOM   2006 O  OD2 . ASP A 1 359 ? 160.027 156.584 139.334 1.00 53.00  ? 359  ASP A OD2 1 
ATOM   2007 N  N   . ALA A 1 360 ? 160.526 160.640 139.921 1.00 50.26  ? 360  ALA A N   1 
ATOM   2008 C  CA  . ALA A 1 360 ? 161.697 161.080 139.170 1.00 50.26  ? 360  ALA A CA  1 
ATOM   2009 C  C   . ALA A 1 360 ? 162.748 161.724 140.062 1.00 50.26  ? 360  ALA A C   1 
ATOM   2010 O  O   . ALA A 1 360 ? 163.942 161.639 139.766 1.00 50.26  ? 360  ALA A O   1 
ATOM   2011 C  CB  . ALA A 1 360 ? 161.282 162.053 138.069 1.00 50.26  ? 360  ALA A CB  1 
ATOM   2012 N  N   . ILE A 1 361 ? 162.331 162.368 141.155 1.00 44.18  ? 361  ILE A N   1 
ATOM   2013 C  CA  . ILE A 1 361 ? 163.293 162.994 142.060 1.00 44.18  ? 361  ILE A CA  1 
ATOM   2014 C  C   . ILE A 1 361 ? 164.196 161.946 142.692 1.00 44.18  ? 361  ILE A C   1 
ATOM   2015 O  O   . ILE A 1 361 ? 165.402 162.162 142.861 1.00 44.18  ? 361  ILE A O   1 
ATOM   2016 C  CB  . ILE A 1 361 ? 162.561 163.819 143.132 1.00 44.18  ? 361  ILE A CB  1 
ATOM   2017 C  CG1 . ILE A 1 361 ? 161.738 164.920 142.483 1.00 44.18  ? 361  ILE A CG1 1 
ATOM   2018 C  CG2 . ILE A 1 361 ? 163.546 164.425 144.103 1.00 44.18  ? 361  ILE A CG2 1 
ATOM   2019 C  CD1 . ILE A 1 361 ? 160.856 165.621 143.454 1.00 44.18  ? 361  ILE A CD1 1 
ATOM   2020 N  N   . GLN A 1 362 ? 163.625 160.799 143.061 1.00 45.40  ? 362  GLN A N   1 
ATOM   2021 C  CA  . GLN A 1 362 ? 164.411 159.747 143.695 1.00 45.40  ? 362  GLN A CA  1 
ATOM   2022 C  C   . GLN A 1 362 ? 165.548 159.286 142.793 1.00 45.40  ? 362  GLN A C   1 
ATOM   2023 O  O   . GLN A 1 362 ? 166.677 159.089 143.256 1.00 45.40  ? 362  GLN A O   1 
ATOM   2024 C  CB  . GLN A 1 362 ? 163.501 158.576 144.059 1.00 45.40  ? 362  GLN A CB  1 
ATOM   2025 C  CG  . GLN A 1 362 ? 164.089 157.610 145.060 1.00 45.40  ? 362  GLN A CG  1 
ATOM   2026 C  CD  . GLN A 1 362 ? 163.459 156.238 144.971 1.00 45.40  ? 362  GLN A CD  1 
ATOM   2027 O  OE1 . GLN A 1 362 ? 162.237 156.105 144.986 1.00 45.40  ? 362  GLN A OE1 1 
ATOM   2028 N  NE2 . GLN A 1 362 ? 164.291 155.208 144.874 1.00 45.40  ? 362  GLN A NE2 1 
ATOM   2029 N  N   . ASN A 1 363 ? 165.271 159.107 141.501 1.00 44.36  ? 363  ASN A N   1 
ATOM   2030 C  CA  . ASN A 1 363 ? 166.329 158.731 140.571 1.00 44.36  ? 363  ASN A CA  1 
ATOM   2031 C  C   . ASN A 1 363 ? 167.231 159.912 140.240 1.00 44.36  ? 363  ASN A C   1 
ATOM   2032 O  O   . ASN A 1 363 ? 168.397 159.717 139.880 1.00 44.36  ? 363  ASN A O   1 
ATOM   2033 C  CB  . ASN A 1 363 ? 165.725 158.152 139.295 1.00 44.36  ? 363  ASN A CB  1 
ATOM   2034 C  CG  . ASN A 1 363 ? 164.890 156.919 139.555 1.00 44.36  ? 363  ASN A CG  1 
ATOM   2035 O  OD1 . ASN A 1 363 ? 163.676 156.929 139.367 1.00 44.36  ? 363  ASN A OD1 1 
ATOM   2036 N  ND2 . ASN A 1 363 ? 165.537 155.847 139.988 1.00 44.36  ? 363  ASN A ND2 1 
ATOM   2037 N  N   . PHE A 1 364 ? 166.710 161.136 140.344 1.00 41.93  ? 364  PHE A N   1 
ATOM   2038 C  CA  . PHE A 1 364 ? 167.508 162.314 140.025 1.00 41.93  ? 364  PHE A CA  1 
ATOM   2039 C  C   . PHE A 1 364 ? 168.587 162.548 141.070 1.00 41.93  ? 364  PHE A C   1 
ATOM   2040 O  O   . PHE A 1 364 ? 169.713 162.928 140.735 1.00 41.93  ? 364  PHE A O   1 
ATOM   2041 C  CB  . PHE A 1 364 ? 166.597 163.533 139.901 1.00 41.93  ? 364  PHE A CB  1 
ATOM   2042 C  CG  . PHE A 1 364 ? 167.236 164.705 139.223 1.00 41.93  ? 364  PHE A CG  1 
ATOM   2043 C  CD1 . PHE A 1 364 ? 167.972 164.535 138.068 1.00 41.93  ? 364  PHE A CD1 1 
ATOM   2044 C  CD2 . PHE A 1 364 ? 167.067 165.981 139.716 1.00 41.93  ? 364  PHE A CD2 1 
ATOM   2045 C  CE1 . PHE A 1 364 ? 168.549 165.611 137.435 1.00 41.93  ? 364  PHE A CE1 1 
ATOM   2046 C  CE2 . PHE A 1 364 ? 167.640 167.058 139.083 1.00 41.93  ? 364  PHE A CE2 1 
ATOM   2047 C  CZ  . PHE A 1 364 ? 168.382 166.873 137.942 1.00 41.93  ? 364  PHE A CZ  1 
ATOM   2048 N  N   . GLY A 1 365 ? 168.258 162.334 142.342 1.00 40.89  ? 365  GLY A N   1 
ATOM   2049 C  CA  . GLY A 1 365 ? 169.259 162.479 143.383 1.00 40.89  ? 365  GLY A CA  1 
ATOM   2050 C  C   . GLY A 1 365 ? 170.350 161.432 143.292 1.00 40.89  ? 365  GLY A C   1 
ATOM   2051 O  O   . GLY A 1 365 ? 171.535 161.742 143.436 1.00 40.89  ? 365  GLY A O   1 
ATOM   2052 N  N   . ALA A 1 366 ? 169.972 160.185 143.034 1.00 42.42  ? 366  ALA A N   1 
ATOM   2053 C  CA  . ALA A 1 366 ? 170.903 159.067 143.046 1.00 42.42  ? 366  ALA A CA  1 
ATOM   2054 C  C   . ALA A 1 366 ? 171.644 158.888 141.730 1.00 42.42  ? 366  ALA A C   1 
ATOM   2055 O  O   . ALA A 1 366 ? 172.470 157.977 141.625 1.00 42.42  ? 366  ALA A O   1 
ATOM   2056 C  CB  . ALA A 1 366 ? 170.162 157.774 143.392 1.00 42.42  ? 366  ALA A CB  1 
ATOM   2057 N  N   . MET A 1 367 ? 171.368 159.718 140.730 1.00 44.01  ? 367  MET A N   1 
ATOM   2058 C  CA  . MET A 1 367 ? 172.012 159.570 139.433 1.00 44.01  ? 367  MET A CA  1 
ATOM   2059 C  C   . MET A 1 367 ? 173.504 159.853 139.541 1.00 44.01  ? 367  MET A C   1 
ATOM   2060 O  O   . MET A 1 367 ? 173.924 160.806 140.202 1.00 44.01  ? 367  MET A O   1 
ATOM   2061 C  CB  . MET A 1 367 ? 171.365 160.510 138.417 1.00 44.01  ? 367  MET A CB  1 
ATOM   2062 C  CG  . MET A 1 367 ? 172.190 160.759 137.174 1.00 44.01  ? 367  MET A CG  1 
ATOM   2063 S  SD  . MET A 1 367 ? 171.428 161.982 136.099 1.00 44.01  ? 367  MET A SD  1 
ATOM   2064 C  CE  . MET A 1 367 ? 171.877 163.488 136.950 1.00 44.01  ? 367  MET A CE  1 
ATOM   2065 N  N   . ASP A 1 368 ? 174.309 159.012 138.888 1.00 45.60  ? 368  ASP A N   1 
ATOM   2066 C  CA  . ASP A 1 368 ? 175.757 159.144 138.938 1.00 45.60  ? 368  ASP A CA  1 
ATOM   2067 C  C   . ASP A 1 368 ? 176.436 159.119 137.579 1.00 45.60  ? 368  ASP A C   1 
ATOM   2068 O  O   . ASP A 1 368 ? 177.648 159.346 137.520 1.00 45.60  ? 368  ASP A O   1 
ATOM   2069 C  CB  . ASP A 1 368 ? 176.370 158.038 139.807 1.00 45.60  ? 368  ASP A CB  1 
ATOM   2070 C  CG  . ASP A 1 368 ? 176.031 156.656 139.306 1.00 45.60  ? 368  ASP A CG  1 
ATOM   2071 O  OD1 . ASP A 1 368 ? 175.048 156.527 138.549 1.00 45.60  ? 368  ASP A OD1 1 
ATOM   2072 O  OD2 . ASP A 1 368 ? 176.745 155.699 139.668 1.00 45.60  ? 368  ASP A OD2 1 
ATOM   2073 N  N   . ILE A 1 369 ? 175.715 158.841 136.497 1.00 43.83  ? 369  ILE A N   1 
ATOM   2074 C  CA  . ILE A 1 369 ? 176.269 158.881 135.149 1.00 43.83  ? 369  ILE A CA  1 
ATOM   2075 C  C   . ILE A 1 369 ? 175.329 159.708 134.290 1.00 43.83  ? 369  ILE A C   1 
ATOM   2076 O  O   . ILE A 1 369 ? 174.118 159.465 134.283 1.00 43.83  ? 369  ILE A O   1 
ATOM   2077 C  CB  . ILE A 1 369 ? 176.449 157.476 134.554 1.00 43.83  ? 369  ILE A CB  1 
ATOM   2078 C  CG1 . ILE A 1 369 ? 177.549 156.719 135.295 1.00 43.83  ? 369  ILE A CG1 1 
ATOM   2079 C  CG2 . ILE A 1 369 ? 176.786 157.564 133.083 1.00 43.83  ? 369  ILE A CG2 1 
ATOM   2080 C  CD1 . ILE A 1 369 ? 177.824 155.347 134.732 1.00 43.83  ? 369  ILE A CD1 1 
ATOM   2081 N  N   . LEU A 1 370 ? 175.877 160.685 133.574 1.00 37.91  ? 370  LEU A N   1 
ATOM   2082 C  CA  . LEU A 1 370 ? 175.090 161.565 132.721 1.00 37.91  ? 370  LEU A CA  1 
ATOM   2083 C  C   . LEU A 1 370 ? 175.599 161.445 131.293 1.00 37.91  ? 370  LEU A C   1 
ATOM   2084 O  O   . LEU A 1 370 ? 176.792 161.638 131.039 1.00 37.91  ? 370  LEU A O   1 
ATOM   2085 C  CB  . LEU A 1 370 ? 175.168 163.012 133.205 1.00 37.91  ? 370  LEU A CB  1 
ATOM   2086 C  CG  . LEU A 1 370 ? 174.300 164.021 132.461 1.00 37.91  ? 370  LEU A CG  1 
ATOM   2087 C  CD1 . LEU A 1 370 ? 172.848 163.812 132.813 1.00 37.91  ? 370  LEU A CD1 1 
ATOM   2088 C  CD2 . LEU A 1 370 ? 174.724 165.431 132.801 1.00 37.91  ? 370  LEU A CD2 1 
ATOM   2089 N  N   . CYS A 1 371 ? 174.697 161.130 130.369 1.00 41.44  ? 371  CYS A N   1 
ATOM   2090 C  CA  . CYS A 1 371 ? 175.019 160.986 128.955 1.00 41.44  ? 371  CYS A CA  1 
ATOM   2091 C  C   . CYS A 1 371 ? 174.317 162.090 128.179 1.00 41.44  ? 371  CYS A C   1 
ATOM   2092 O  O   . CYS A 1 371 ? 173.084 162.125 128.127 1.00 41.44  ? 371  CYS A O   1 
ATOM   2093 C  CB  . CYS A 1 371 ? 174.595 159.613 128.440 1.00 41.44  ? 371  CYS A CB  1 
ATOM   2094 S  SG  . CYS A 1 371 ? 175.186 158.233 129.437 1.00 41.44  ? 371  CYS A SG  1 
ATOM   2095 N  N   . THR A 1 372 ? 175.096 162.981 127.573 1.00 44.66  ? 372  THR A N   1 
ATOM   2096 C  CA  . THR A 1 372 ? 174.543 164.134 126.881 1.00 44.66  ? 372  THR A CA  1 
ATOM   2097 C  C   . THR A 1 372 ? 175.234 164.321 125.541 1.00 44.66  ? 372  THR A C   1 
ATOM   2098 O  O   . THR A 1 372 ? 176.388 163.927 125.359 1.00 44.66  ? 372  THR A O   1 
ATOM   2099 C  CB  . THR A 1 372 ? 174.696 165.415 127.706 1.00 44.66  ? 372  THR A CB  1 
ATOM   2100 O  OG1 . THR A 1 372 ? 174.457 166.551 126.868 1.00 44.66  ? 372  THR A OG1 1 
ATOM   2101 C  CG2 . THR A 1 372 ? 176.097 165.512 128.283 1.00 44.66  ? 372  THR A CG2 1 
ATOM   2102 N  N   . ASP A 1 373 ? 174.514 164.929 124.604 1.00 47.83  ? 373  ASP A N   1 
ATOM   2103 C  CA  . ASP A 1 373 ? 175.112 165.349 123.347 1.00 47.83  ? 373  ASP A CA  1 
ATOM   2104 C  C   . ASP A 1 373 ? 175.811 166.690 123.535 1.00 47.83  ? 373  ASP A C   1 
ATOM   2105 O  O   . ASP A 1 373 ? 175.443 167.488 124.400 1.00 47.83  ? 373  ASP A O   1 
ATOM   2106 C  CB  . ASP A 1 373 ? 174.050 165.447 122.252 1.00 47.83  ? 373  ASP A CB  1 
ATOM   2107 C  CG  . ASP A 1 373 ? 174.647 165.648 120.875 1.00 47.83  ? 373  ASP A CG  1 
ATOM   2108 O  OD1 . ASP A 1 373 ? 175.886 165.582 120.748 1.00 47.83  ? 373  ASP A OD1 1 
ATOM   2109 O  OD2 . ASP A 1 373 ? 173.878 165.869 119.916 1.00 47.83  ? 373  ASP A OD2 1 
ATOM   2110 N  N   . LYS A 1 374 ? 176.837 166.933 122.718 1.00 50.38  ? 374  LYS A N   1 
ATOM   2111 C  CA  . LYS A 1 374 ? 177.687 168.095 122.956 1.00 50.38  ? 374  LYS A CA  1 
ATOM   2112 C  C   . LYS A 1 374 ? 177.004 169.393 122.543 1.00 50.38  ? 374  LYS A C   1 
ATOM   2113 O  O   . LYS A 1 374 ? 177.174 170.422 123.207 1.00 50.38  ? 374  LYS A O   1 
ATOM   2114 C  CB  . LYS A 1 374 ? 179.023 167.935 122.232 1.00 50.38  ? 374  LYS A CB  1 
ATOM   2115 C  CG  . LYS A 1 374 ? 178.930 167.899 120.721 1.00 50.38  ? 374  LYS A CG  1 
ATOM   2116 C  CD  . LYS A 1 374 ? 180.307 167.929 120.093 1.00 50.38  ? 374  LYS A CD  1 
ATOM   2117 C  CE  . LYS A 1 374 ? 180.218 167.834 118.585 1.00 50.38  ? 374  LYS A CE  1 
ATOM   2118 N  NZ  . LYS A 1 374 ? 179.493 168.992 118.001 1.00 50.38  ? 374  LYS A NZ  1 
ATOM   2119 N  N   . THR A 1 375 ? 176.232 169.376 121.461 1.00 48.85  ? 375  THR A N   1 
ATOM   2120 C  CA  . THR A 1 375 ? 175.651 170.611 120.948 1.00 48.85  ? 375  THR A CA  1 
ATOM   2121 C  C   . THR A 1 375 ? 174.552 171.099 121.881 1.00 48.85  ? 375  THR A C   1 
ATOM   2122 O  O   . THR A 1 375 ? 173.558 170.401 122.100 1.00 48.85  ? 375  THR A O   1 
ATOM   2123 C  CB  . THR A 1 375 ? 175.097 170.400 119.543 1.00 48.85  ? 375  THR A CB  1 
ATOM   2124 O  OG1 . THR A 1 375 ? 174.032 169.444 119.587 1.00 48.85  ? 375  THR A OG1 1 
ATOM   2125 C  CG2 . THR A 1 375 ? 176.185 169.899 118.611 1.00 48.85  ? 375  THR A CG2 1 
ATOM   2126 N  N   . GLY A 1 376 ? 174.729 172.299 122.424 1.00 51.97  ? 376  GLY A N   1 
ATOM   2127 C  CA  . GLY A 1 376 ? 173.753 172.906 123.292 1.00 51.97  ? 376  GLY A CA  1 
ATOM   2128 C  C   . GLY A 1 376 ? 174.019 172.748 124.772 1.00 51.97  ? 376  GLY A C   1 
ATOM   2129 O  O   . GLY A 1 376 ? 173.494 173.533 125.567 1.00 51.97  ? 376  GLY A O   1 
ATOM   2130 N  N   . THR A 1 377 ? 174.823 171.764 125.169 1.00 50.61  ? 377  THR A N   1 
ATOM   2131 C  CA  . THR A 1 377 ? 175.192 171.568 126.564 1.00 50.61  ? 377  THR A CA  1 
ATOM   2132 C  C   . THR A 1 377 ? 176.649 171.909 126.828 1.00 50.61  ? 377  THR A C   1 
ATOM   2133 O  O   . THR A 1 377 ? 176.949 172.705 127.721 1.00 50.61  ? 377  THR A O   1 
ATOM   2134 C  CB  . THR A 1 377 ? 174.918 170.121 126.990 1.00 50.61  ? 377  THR A CB  1 
ATOM   2135 O  OG1 . THR A 1 377 ? 175.791 169.243 126.273 1.00 50.61  ? 377  THR A OG1 1 
ATOM   2136 C  CG2 . THR A 1 377 ? 173.482 169.744 126.687 1.00 50.61  ? 377  THR A CG2 1 
ATOM   2137 N  N   . LEU A 1 378 ? 177.571 171.320 126.067 1.00 54.64  ? 378  LEU A N   1 
ATOM   2138 C  CA  . LEU A 1 378 ? 178.971 171.710 126.168 1.00 54.64  ? 378  LEU A CA  1 
ATOM   2139 C  C   . LEU A 1 378 ? 179.253 172.973 125.364 1.00 54.64  ? 378  LEU A C   1 
ATOM   2140 O  O   . LEU A 1 378 ? 179.964 173.866 125.835 1.00 54.64  ? 378  LEU A O   1 
ATOM   2141 C  CB  . LEU A 1 378 ? 179.871 170.572 125.693 1.00 54.64  ? 378  LEU A CB  1 
ATOM   2142 C  CG  . LEU A 1 378 ? 180.396 169.582 126.731 1.00 54.64  ? 378  LEU A CG  1 
ATOM   2143 C  CD1 . LEU A 1 378 ? 179.263 168.992 127.546 1.00 54.64  ? 378  LEU A CD1 1 
ATOM   2144 C  CD2 . LEU A 1 378 ? 181.188 168.489 126.048 1.00 54.64  ? 378  LEU A CD2 1 
ATOM   2145 N  N   . THR A 1 379 ? 178.708 173.066 124.155 1.00 58.36  ? 379  THR A N   1 
ATOM   2146 C  CA  . THR A 1 379 ? 178.920 174.203 123.274 1.00 58.36  ? 379  THR A CA  1 
ATOM   2147 C  C   . THR A 1 379 ? 177.609 174.940 123.054 1.00 58.36  ? 379  THR A C   1 
ATOM   2148 O  O   . THR A 1 379 ? 176.567 174.315 122.840 1.00 58.36  ? 379  THR A O   1 
ATOM   2149 C  CB  . THR A 1 379 ? 179.475 173.763 121.922 1.00 58.36  ? 379  THR A CB  1 
ATOM   2150 O  OG1 . THR A 1 379 ? 178.393 173.368 121.073 1.00 58.36  ? 379  THR A OG1 1 
ATOM   2151 C  CG2 . THR A 1 379 ? 180.409 172.594 122.094 1.00 58.36  ? 379  THR A CG2 1 
ATOM   2152 N  N   . GLN A 1 380 ? 177.665 176.268 123.098 1.00 68.81  ? 380  GLN A N   1 
ATOM   2153 C  CA  . GLN A 1 380 ? 176.481 177.062 122.811 1.00 68.81  ? 380  GLN A CA  1 
ATOM   2154 C  C   . GLN A 1 380 ? 176.063 176.862 121.361 1.00 68.81  ? 380  GLN A C   1 
ATOM   2155 O  O   . GLN A 1 380 ? 176.893 176.644 120.475 1.00 68.81  ? 380  GLN A O   1 
ATOM   2156 C  CB  . GLN A 1 380 ? 176.741 178.541 123.097 1.00 68.81  ? 380  GLN A CB  1 
ATOM   2157 C  CG  . GLN A 1 380 ? 177.617 179.239 122.076 1.00 68.81  ? 380  GLN A CG  1 
ATOM   2158 C  CD  . GLN A 1 380 ? 178.200 180.536 122.600 1.00 68.81  ? 380  GLN A CD  1 
ATOM   2159 O  OE1 . GLN A 1 380 ? 178.270 181.532 121.882 1.00 68.81  ? 380  GLN A OE1 1 
ATOM   2160 N  NE2 . GLN A 1 380 ? 178.623 180.529 123.858 1.00 68.81  ? 380  GLN A NE2 1 
ATOM   2161 N  N   . ASP A 1 381 ? 174.755 176.918 121.121 1.00 76.03  ? 381  ASP A N   1 
ATOM   2162 C  CA  . ASP A 1 381 ? 174.254 176.638 119.784 1.00 76.03  ? 381  ASP A CA  1 
ATOM   2163 C  C   . ASP A 1 381 ? 174.525 177.769 118.801 1.00 76.03  ? 381  ASP A C   1 
ATOM   2164 O  O   . ASP A 1 381 ? 174.299 177.584 117.601 1.00 76.03  ? 381  ASP A O   1 
ATOM   2165 C  CB  . ASP A 1 381 ? 172.758 176.333 119.836 1.00 76.03  ? 381  ASP A CB  1 
ATOM   2166 C  CG  . ASP A 1 381 ? 172.330 175.356 118.763 1.00 76.03  ? 381  ASP A CG  1 
ATOM   2167 O  OD1 . ASP A 1 381 ? 173.201 174.904 117.991 1.00 76.03  ? 381  ASP A OD1 1 
ATOM   2168 O  OD2 . ASP A 1 381 ? 171.127 175.033 118.694 1.00 76.03  ? 381  ASP A OD2 1 
ATOM   2169 N  N   . LYS A 1 382 ? 174.987 178.926 119.273 1.00 79.72  ? 382  LYS A N   1 
ATOM   2170 C  CA  . LYS A 1 382 ? 175.442 179.969 118.361 1.00 79.72  ? 382  LYS A CA  1 
ATOM   2171 C  C   . LYS A 1 382 ? 176.605 179.440 117.537 1.00 79.72  ? 382  LYS A C   1 
ATOM   2172 O  O   . LYS A 1 382 ? 177.555 178.869 118.080 1.00 79.72  ? 382  LYS A O   1 
ATOM   2173 C  CB  . LYS A 1 382 ? 175.868 181.226 119.128 1.00 79.72  ? 382  LYS A CB  1 
ATOM   2174 C  CG  . LYS A 1 382 ? 174.932 181.735 120.240 1.00 79.72  ? 382  LYS A CG  1 
ATOM   2175 C  CD  . LYS A 1 382 ? 173.459 181.392 120.030 1.00 79.72  ? 382  LYS A CD  1 
ATOM   2176 C  CE  . LYS A 1 382 ? 172.601 181.950 121.153 1.00 79.72  ? 382  LYS A CE  1 
ATOM   2177 N  NZ  . LYS A 1 382 ? 172.514 181.013 122.307 1.00 79.72  ? 382  LYS A NZ  1 
ATOM   2178 N  N   . ILE A 1 383 ? 176.534 179.624 116.223 1.00 87.40  ? 383  ILE A N   1 
ATOM   2179 C  CA  . ILE A 1 383 ? 177.474 179.000 115.293 1.00 87.40  ? 383  ILE A CA  1 
ATOM   2180 C  C   . ILE A 1 383 ? 178.039 180.113 114.414 1.00 87.40  ? 383  ILE A C   1 
ATOM   2181 O  O   . ILE A 1 383 ? 177.402 180.564 113.455 1.00 87.40  ? 383  ILE A O   1 
ATOM   2182 C  CB  . ILE A 1 383 ? 176.827 177.887 114.462 1.00 87.40  ? 383  ILE A CB  1 
ATOM   2183 C  CG1 . ILE A 1 383 ? 177.709 177.520 113.274 1.00 87.40  ? 383  ILE A CG1 1 
ATOM   2184 C  CG2 . ILE A 1 383 ? 175.428 178.272 114.028 1.00 87.40  ? 383  ILE A CG2 1 
ATOM   2185 C  CD1 . ILE A 1 383 ? 179.040 176.976 113.701 1.00 87.40  ? 383  ILE A CD1 1 
ATOM   2186 N  N   . VAL A 1 384 ? 179.245 180.560 114.740 1.00 90.84  ? 384  VAL A N   1 
ATOM   2187 C  CA  . VAL A 1 384 ? 179.897 181.609 113.974 1.00 90.84  ? 384  VAL A CA  1 
ATOM   2188 C  C   . VAL A 1 384 ? 180.618 180.983 112.796 1.00 90.84  ? 384  VAL A C   1 
ATOM   2189 O  O   . VAL A 1 384 ? 180.759 179.766 112.729 1.00 90.84  ? 384  VAL A O   1 
ATOM   2190 C  CB  . VAL A 1 384 ? 180.919 182.366 114.828 1.00 90.84  ? 384  VAL A CB  1 
ATOM   2191 C  CG1 . VAL A 1 384 ? 180.226 183.034 116.003 1.00 90.84  ? 384  VAL A CG1 1 
ATOM   2192 C  CG2 . VAL A 1 384 ? 181.996 181.413 115.316 1.00 90.84  ? 384  VAL A CG2 1 
ATOM   2193 N  N   . LEU A 1 385 ? 181.082 181.808 111.866 1.00 102.81 ? 385  LEU A N   1 
ATOM   2194 C  CA  . LEU A 1 385 ? 181.780 181.285 110.702 1.00 102.81 ? 385  LEU A CA  1 
ATOM   2195 C  C   . LEU A 1 385 ? 183.241 181.682 110.702 1.00 102.81 ? 385  LEU A C   1 
ATOM   2196 O  O   . LEU A 1 385 ? 183.569 182.861 110.763 1.00 102.81 ? 385  LEU A O   1 
ATOM   2197 C  CB  . LEU A 1 385 ? 181.119 181.781 109.420 1.00 102.81 ? 385  LEU A CB  1 
ATOM   2198 C  CG  . LEU A 1 385 ? 181.902 181.514 108.136 1.00 102.81 ? 385  LEU A CG  1 
ATOM   2199 C  CD1 . LEU A 1 385 ? 180.976 181.548 106.932 1.00 102.81 ? 385  LEU A CD1 1 
ATOM   2200 C  CD2 . LEU A 1 385 ? 183.049 182.500 107.975 1.00 102.81 ? 385  LEU A CD2 1 
ATOM   2201 N  N   . GLU A 1 386 ? 184.120 180.692 110.621 1.00 109.21 ? 386  GLU A N   1 
ATOM   2202 C  CA  . GLU A 1 386 ? 185.545 180.966 110.609 1.00 109.21 ? 386  GLU A CA  1 
ATOM   2203 C  C   . GLU A 1 386 ? 186.255 180.309 109.428 1.00 109.21 ? 386  GLU A C   1 
ATOM   2204 O  O   . GLU A 1 386 ? 186.092 179.110 109.199 1.00 109.21 ? 386  GLU A O   1 
ATOM   2205 C  CB  . GLU A 1 386 ? 186.159 180.513 111.932 1.00 109.21 ? 386  GLU A CB  1 
ATOM   2206 C  CG  . GLU A 1 386 ? 187.557 181.034 112.193 1.00 109.21 ? 386  GLU A CG  1 
ATOM   2207 C  CD  . GLU A 1 386 ? 188.617 180.189 111.527 1.00 109.21 ? 386  GLU A CD  1 
ATOM   2208 O  OE1 . GLU A 1 386 ? 189.813 180.516 111.667 1.00 109.21 ? 386  GLU A OE1 1 
ATOM   2209 O  OE2 . GLU A 1 386 ? 188.254 179.196 110.867 1.00 109.21 ? 386  GLU A OE2 1 
ATOM   2210 N  N   . ASN A 1 387 ? 186.955 181.147 108.657 1.00 114.65 ? 387  ASN A N   1 
ATOM   2211 C  CA  . ASN A 1 387 ? 187.800 180.817 107.485 1.00 114.65 ? 387  ASN A CA  1 
ATOM   2212 C  C   . ASN A 1 387 ? 187.128 180.606 106.128 1.00 114.65 ? 387  ASN A C   1 
ATOM   2213 O  O   . ASN A 1 387 ? 185.966 180.219 106.041 1.00 114.65 ? 387  ASN A O   1 
ATOM   2214 C  CB  . ASN A 1 387 ? 188.875 179.750 107.757 1.00 114.65 ? 387  ASN A CB  1 
ATOM   2215 C  CG  . ASN A 1 387 ? 190.082 180.317 108.465 1.00 114.65 ? 387  ASN A CG  1 
ATOM   2216 O  OD1 . ASN A 1 387 ? 190.114 181.498 108.806 1.00 114.65 ? 387  ASN A OD1 1 
ATOM   2217 N  ND2 . ASN A 1 387 ? 191.084 179.478 108.692 1.00 114.65 ? 387  ASN A ND2 1 
ATOM   2218 N  N   . HIS A 1 388 ? 187.897 180.855 105.074 1.00 124.95 ? 388  HIS A N   1 
ATOM   2219 C  CA  . HIS A 1 388 ? 187.453 180.676 103.700 1.00 124.95 ? 388  HIS A CA  1 
ATOM   2220 C  C   . HIS A 1 388 ? 188.568 179.940 102.980 1.00 124.95 ? 388  HIS A C   1 
ATOM   2221 O  O   . HIS A 1 388 ? 189.279 180.531 102.167 1.00 124.95 ? 388  HIS A O   1 
ATOM   2222 C  CB  . HIS A 1 388 ? 187.221 182.021 103.011 1.00 124.95 ? 388  HIS A CB  1 
ATOM   2223 C  CG  . HIS A 1 388 ? 186.415 182.988 103.818 1.00 124.95 ? 388  HIS A CG  1 
ATOM   2224 N  ND1 . HIS A 1 388 ? 186.964 184.107 104.404 1.00 124.95 ? 388  HIS A ND1 1 
ATOM   2225 C  CD2 . HIS A 1 388 ? 185.102 182.999 104.143 1.00 124.95 ? 388  HIS A CD2 1 
ATOM   2226 C  CE1 . HIS A 1 388 ? 186.023 184.769 105.051 1.00 124.95 ? 388  HIS A CE1 1 
ATOM   2227 N  NE2 . HIS A 1 388 ? 184.883 184.118 104.908 1.00 124.95 ? 388  HIS A NE2 1 
ATOM   2228 N  N   . THR A 1 389 ? 188.733 178.658 103.276 1.00 131.67 ? 389  THR A N   1 
ATOM   2229 C  CA  . THR A 1 389 ? 189.810 177.895 102.659 1.00 131.67 ? 389  THR A CA  1 
ATOM   2230 C  C   . THR A 1 389 ? 189.377 177.040 101.483 1.00 131.67 ? 389  THR A C   1 
ATOM   2231 O  O   . THR A 1 389 ? 188.262 176.520 101.449 1.00 131.67 ? 389  THR A O   1 
ATOM   2232 C  CB  . THR A 1 389 ? 190.487 176.960 103.674 1.00 131.67 ? 389  THR A CB  1 
ATOM   2233 O  OG1 . THR A 1 389 ? 189.637 175.835 103.923 1.00 131.67 ? 389  THR A OG1 1 
ATOM   2234 C  CG2 . THR A 1 389 ? 190.761 177.692 104.979 1.00 131.67 ? 389  THR A CG2 1 
ATOM   2235 N  N   . ASP A 1 390 ? 190.283 176.896 100.520 1.00 136.73 ? 390  ASP A N   1 
ATOM   2236 C  CA  . ASP A 1 390 ? 190.037 176.065 99.352  1.00 136.73 ? 390  ASP A CA  1 
ATOM   2237 C  C   . ASP A 1 390 ? 190.593 174.668 99.623  1.00 136.73 ? 390  ASP A C   1 
ATOM   2238 O  O   . ASP A 1 390 ? 190.924 174.315 100.758 1.00 136.73 ? 390  ASP A O   1 
ATOM   2239 C  CB  . ASP A 1 390 ? 190.647 176.703 98.107  1.00 136.73 ? 390  ASP A CB  1 
ATOM   2240 C  CG  . ASP A 1 390 ? 192.121 177.021 98.274  1.00 136.73 ? 390  ASP A CG  1 
ATOM   2241 O  OD1 . ASP A 1 390 ? 192.660 176.809 99.382  1.00 136.73 ? 390  ASP A OD1 1 
ATOM   2242 O  OD2 . ASP A 1 390 ? 192.744 177.482 97.295  1.00 136.73 ? 390  ASP A OD2 1 
ATOM   2243 N  N   . ILE A 1 391 ? 190.696 173.848 98.575  1.00 139.03 ? 391  ILE A N   1 
ATOM   2244 C  CA  . ILE A 1 391 ? 191.279 172.521 98.739  1.00 139.03 ? 391  ILE A CA  1 
ATOM   2245 C  C   . ILE A 1 391 ? 192.737 172.626 99.160  1.00 139.03 ? 391  ILE A C   1 
ATOM   2246 O  O   . ILE A 1 391 ? 193.229 171.802 99.941  1.00 139.03 ? 391  ILE A O   1 
ATOM   2247 C  CB  . ILE A 1 391 ? 191.122 171.704 97.444  1.00 139.03 ? 391  ILE A CB  1 
ATOM   2248 C  CG1 . ILE A 1 391 ? 191.452 172.568 96.228  1.00 139.03 ? 391  ILE A CG1 1 
ATOM   2249 C  CG2 . ILE A 1 391 ? 189.712 171.152 97.336  1.00 139.03 ? 391  ILE A CG2 1 
ATOM   2250 C  CD1 . ILE A 1 391 ? 191.247 171.862 94.911  1.00 139.03 ? 391  ILE A CD1 1 
ATOM   2251 N  N   . SER A 1 392 ? 193.450 173.637 98.662  1.00 137.40 ? 392  SER A N   1 
ATOM   2252 C  CA  . SER A 1 392 ? 194.843 173.844 99.031  1.00 137.40 ? 392  SER A CA  1 
ATOM   2253 C  C   . SER A 1 392 ? 195.007 174.426 100.428 1.00 137.40 ? 392  SER A C   1 
ATOM   2254 O  O   . SER A 1 392 ? 196.137 174.491 100.924 1.00 137.40 ? 392  SER A O   1 
ATOM   2255 C  CB  . SER A 1 392 ? 195.525 174.763 98.015  1.00 137.40 ? 392  SER A CB  1 
ATOM   2256 O  OG  . SER A 1 392 ? 195.107 176.106 98.186  1.00 137.40 ? 392  SER A OG  1 
ATOM   2257 N  N   . GLY A 1 393 ? 193.921 174.850 101.068 1.00 135.10 ? 393  GLY A N   1 
ATOM   2258 C  CA  . GLY A 1 393 ? 193.987 175.417 102.396 1.00 135.10 ? 393  GLY A CA  1 
ATOM   2259 C  C   . GLY A 1 393 ? 194.333 176.888 102.451 1.00 135.10 ? 393  GLY A C   1 
ATOM   2260 O  O   . GLY A 1 393 ? 194.378 177.454 103.550 1.00 135.10 ? 393  GLY A O   1 
ATOM   2261 N  N   . LYS A 1 394 ? 194.577 177.524 101.310 1.00 134.80 ? 394  LYS A N   1 
ATOM   2262 C  CA  . LYS A 1 394 ? 194.868 178.948 101.267 1.00 134.80 ? 394  LYS A CA  1 
ATOM   2263 C  C   . LYS A 1 394 ? 193.583 179.748 101.422 1.00 134.80 ? 394  LYS A C   1 
ATOM   2264 O  O   . LYS A 1 394 ? 192.511 179.314 100.992 1.00 134.80 ? 394  LYS A O   1 
ATOM   2265 C  CB  . LYS A 1 394 ? 195.563 179.319 99.957  1.00 134.80 ? 394  LYS A CB  1 
ATOM   2266 N  N   . THR A 1 395 ? 193.697 180.920 102.041 1.00 132.92 ? 395  THR A N   1 
ATOM   2267 C  CA  . THR A 1 395 ? 192.542 181.785 102.267 1.00 132.92 ? 395  THR A CA  1 
ATOM   2268 C  C   . THR A 1 395 ? 192.107 182.382 100.935 1.00 132.92 ? 395  THR A C   1 
ATOM   2269 O  O   . THR A 1 395 ? 192.731 183.312 100.421 1.00 132.92 ? 395  THR A O   1 
ATOM   2270 C  CB  . THR A 1 395 ? 192.880 182.877 103.276 1.00 132.92 ? 395  THR A CB  1 
ATOM   2271 O  OG1 . THR A 1 395 ? 193.737 182.341 104.291 1.00 132.92 ? 395  THR A OG1 1 
ATOM   2272 C  CG2 . THR A 1 395 ? 191.611 183.408 103.924 1.00 132.92 ? 395  THR A CG2 1 
ATOM   2273 N  N   . SER A 1 396 ? 191.029 181.845 100.368 1.00 134.95 ? 396  SER A N   1 
ATOM   2274 C  CA  . SER A 1 396 ? 190.527 182.263 99.067  1.00 134.95 ? 396  SER A CA  1 
ATOM   2275 C  C   . SER A 1 396 ? 189.145 182.880 99.225  1.00 134.95 ? 396  SER A C   1 
ATOM   2276 O  O   . SER A 1 396 ? 188.288 182.325 99.921  1.00 134.95 ? 396  SER A O   1 
ATOM   2277 C  CB  . SER A 1 396 ? 190.479 181.085 98.092  1.00 134.95 ? 396  SER A CB  1 
ATOM   2278 O  OG  . SER A 1 396 ? 190.036 181.503 96.814  1.00 134.95 ? 396  SER A OG  1 
ATOM   2279 N  N   . GLU A 1 397 ? 188.934 184.025 98.572  1.00 139.68 ? 397  GLU A N   1 
ATOM   2280 C  CA  . GLU A 1 397 ? 187.678 184.753 98.723  1.00 139.68 ? 397  GLU A CA  1 
ATOM   2281 C  C   . GLU A 1 397 ? 186.656 184.300 97.682  1.00 139.68 ? 397  GLU A C   1 
ATOM   2282 O  O   . GLU A 1 397 ? 185.439 184.448 97.875  1.00 139.68 ? 397  GLU A O   1 
ATOM   2283 C  CB  . GLU A 1 397 ? 187.959 186.257 98.622  1.00 139.68 ? 397  GLU A CB  1 
ATOM   2284 C  CG  . GLU A 1 397 ? 186.804 187.240 98.866  1.00 139.68 ? 397  GLU A CG  1 
ATOM   2285 C  CD  . GLU A 1 397 ? 185.751 186.790 99.874  1.00 139.68 ? 397  GLU A CD  1 
ATOM   2286 O  OE1 . GLU A 1 397 ? 186.059 186.000 100.793 1.00 139.68 ? 397  GLU A OE1 1 
ATOM   2287 O  OE2 . GLU A 1 397 ? 184.593 187.238 99.740  1.00 139.68 ? 397  GLU A OE2 1 
ATOM   2288 N  N   . ARG A 1 398 ? 187.135 183.733 96.570  1.00 141.03 ? 398  ARG A N   1 
ATOM   2289 C  CA  . ARG A 1 398 ? 186.229 183.171 95.573  1.00 141.03 ? 398  ARG A CA  1 
ATOM   2290 C  C   . ARG A 1 398 ? 185.399 182.036 96.155  1.00 141.03 ? 398  ARG A C   1 
ATOM   2291 O  O   . ARG A 1 398 ? 184.279 181.784 95.694  1.00 141.03 ? 398  ARG A O   1 
ATOM   2292 C  CB  . ARG A 1 398 ? 187.019 182.690 94.354  1.00 141.03 ? 398  ARG A CB  1 
ATOM   2293 C  CG  . ARG A 1 398 ? 187.766 181.384 94.565  1.00 141.03 ? 398  ARG A CG  1 
ATOM   2294 C  CD  . ARG A 1 398 ? 188.117 180.718 93.247  1.00 141.03 ? 398  ARG A CD  1 
ATOM   2295 N  NE  . ARG A 1 398 ? 186.930 180.276 92.524  1.00 141.03 ? 398  ARG A NE  1 
ATOM   2296 C  CZ  . ARG A 1 398 ? 186.958 179.603 91.383  1.00 141.03 ? 398  ARG A CZ  1 
ATOM   2297 N  NH1 . ARG A 1 398 ? 188.100 179.272 90.803  1.00 141.03 ? 398  ARG A NH1 1 
ATOM   2298 N  NH2 . ARG A 1 398 ? 185.811 179.251 90.810  1.00 141.03 ? 398  ARG A NH2 1 
ATOM   2299 N  N   . VAL A 1 399 ? 185.923 181.348 97.170  1.00 140.05 ? 399  VAL A N   1 
ATOM   2300 C  CA  . VAL A 1 399 ? 185.123 180.357 97.883  1.00 140.05 ? 399  VAL A CA  1 
ATOM   2301 C  C   . VAL A 1 399 ? 183.937 181.033 98.558  1.00 140.05 ? 399  VAL A C   1 
ATOM   2302 O  O   . VAL A 1 399 ? 182.825 180.495 98.584  1.00 140.05 ? 399  VAL A O   1 
ATOM   2303 C  CB  . VAL A 1 399 ? 185.991 179.589 98.895  1.00 140.05 ? 399  VAL A CB  1 
ATOM   2304 C  CG1 . VAL A 1 399 ? 185.324 178.278 99.267  1.00 140.05 ? 399  VAL A CG1 1 
ATOM   2305 C  CG2 . VAL A 1 399 ? 187.374 179.342 98.323  1.00 140.05 ? 399  VAL A CG2 1 
ATOM   2306 N  N   . LEU A 1 400 ? 184.158 182.226 99.116  1.00 139.43 ? 400  LEU A N   1 
ATOM   2307 C  CA  . LEU A 1 400 ? 183.048 182.977 99.692  1.00 139.43 ? 400  LEU A CA  1 
ATOM   2308 C  C   . LEU A 1 400 ? 182.051 183.404 98.625  1.00 139.43 ? 400  LEU A C   1 
ATOM   2309 O  O   . LEU A 1 400 ? 180.839 183.365 98.860  1.00 139.43 ? 400  LEU A O   1 
ATOM   2310 C  CB  . LEU A 1 400 ? 183.550 184.203 100.448 1.00 139.43 ? 400  LEU A CB  1 
ATOM   2311 C  CG  . LEU A 1 400 ? 182.594 184.668 101.548 1.00 139.43 ? 400  LEU A CG  1 
ATOM   2312 C  CD1 . LEU A 1 400 ? 182.199 183.508 102.453 1.00 139.43 ? 400  LEU A CD1 1 
ATOM   2313 C  CD2 . LEU A 1 400 ? 183.154 185.841 102.340 1.00 139.43 ? 400  LEU A CD2 1 
ATOM   2314 N  N   . HIS A 1 401 ? 182.533 183.838 97.454  1.00 143.03 ? 401  HIS A N   1 
ATOM   2315 C  CA  . HIS A 1 401 ? 181.594 184.141 96.373  1.00 143.03 ? 401  HIS A CA  1 
ATOM   2316 C  C   . HIS A 1 401 ? 180.754 182.923 96.014  1.00 143.03 ? 401  HIS A C   1 
ATOM   2317 O  O   . HIS A 1 401 ? 179.535 183.031 95.835  1.00 143.03 ? 401  HIS A O   1 
ATOM   2318 C  CB  . HIS A 1 401 ? 182.310 184.663 95.124  1.00 143.03 ? 401  HIS A CB  1 
ATOM   2319 C  CG  . HIS A 1 401 ? 183.094 185.919 95.334  1.00 143.03 ? 401  HIS A CG  1 
ATOM   2320 N  ND1 . HIS A 1 401 ? 182.502 187.138 95.583  1.00 143.03 ? 401  HIS A ND1 1 
ATOM   2321 C  CD2 . HIS A 1 401 ? 184.428 186.149 95.301  1.00 143.03 ? 401  HIS A CD2 1 
ATOM   2322 C  CE1 . HIS A 1 401 ? 183.437 188.062 95.700  1.00 143.03 ? 401  HIS A CE1 1 
ATOM   2323 N  NE2 . HIS A 1 401 ? 184.616 187.487 95.541  1.00 143.03 ? 401  HIS A NE2 1 
ATOM   2324 N  N   . SER A 1 402 ? 181.387 181.756 95.903  1.00 144.08 ? 402  SER A N   1 
ATOM   2325 C  CA  . SER A 1 402 ? 180.646 180.544 95.568  1.00 144.08 ? 402  SER A CA  1 
ATOM   2326 C  C   . SER A 1 402 ? 179.632 180.196 96.652  1.00 144.08 ? 402  SER A C   1 
ATOM   2327 O  O   . SER A 1 402 ? 178.502 179.797 96.348  1.00 144.08 ? 402  SER A O   1 
ATOM   2328 C  CB  . SER A 1 402 ? 181.615 179.385 95.345  1.00 144.08 ? 402  SER A CB  1 
ATOM   2329 O  OG  . SER A 1 402 ? 182.604 179.724 94.389  1.00 144.08 ? 402  SER A OG  1 
ATOM   2330 N  N   . ALA A 1 403 ? 180.017 180.346 97.921  1.00 142.74 ? 403  ALA A N   1 
ATOM   2331 C  CA  . ALA A 1 403 ? 179.142 179.940 99.016  1.00 142.74 ? 403  ALA A CA  1 
ATOM   2332 C  C   . ALA A 1 403 ? 177.980 180.909 99.198  1.00 142.74 ? 403  ALA A C   1 
ATOM   2333 O  O   . ALA A 1 403 ? 176.873 180.498 99.565  1.00 142.74 ? 403  ALA A O   1 
ATOM   2334 C  CB  . ALA A 1 403 ? 179.946 179.822 100.310 1.00 142.74 ? 403  ALA A CB  1 
ATOM   2335 N  N   . TRP A 1 404 ? 178.214 182.199 98.951  1.00 145.84 ? 404  TRP A N   1 
ATOM   2336 C  CA  . TRP A 1 404 ? 177.214 183.219 99.249  1.00 145.84 ? 404  TRP A CA  1 
ATOM   2337 C  C   . TRP A 1 404 ? 175.958 183.041 98.406  1.00 145.84 ? 404  TRP A C   1 
ATOM   2338 O  O   . TRP A 1 404 ? 174.838 183.241 98.890  1.00 145.84 ? 404  TRP A O   1 
ATOM   2339 C  CB  . TRP A 1 404 ? 177.821 184.606 99.033  1.00 145.84 ? 404  TRP A CB  1 
ATOM   2340 C  CG  . TRP A 1 404 ? 176.956 185.724 99.505  1.00 145.84 ? 404  TRP A CG  1 
ATOM   2341 C  CD1 . TRP A 1 404 ? 177.042 186.377 100.696 1.00 145.84 ? 404  TRP A CD1 1 
ATOM   2342 C  CD2 . TRP A 1 404 ? 175.888 186.346 98.782  1.00 145.84 ? 404  TRP A CD2 1 
ATOM   2343 N  NE1 . TRP A 1 404 ? 176.086 187.359 100.769 1.00 145.84 ? 404  TRP A NE1 1 
ATOM   2344 C  CE2 . TRP A 1 404 ? 175.363 187.360 99.605  1.00 145.84 ? 404  TRP A CE2 1 
ATOM   2345 C  CE3 . TRP A 1 404 ? 175.321 186.140 97.520  1.00 145.84 ? 404  TRP A CE3 1 
ATOM   2346 C  CZ2 . TRP A 1 404 ? 174.296 188.164 99.210  1.00 145.84 ? 404  TRP A CZ2 1 
ATOM   2347 C  CZ3 . TRP A 1 404 ? 174.265 186.942 97.129  1.00 145.84 ? 404  TRP A CZ3 1 
ATOM   2348 C  CH2 . TRP A 1 404 ? 173.764 187.941 97.971  1.00 145.84 ? 404  TRP A CH2 1 
ATOM   2349 N  N   . LEU A 1 405 ? 176.129 182.690 97.131  1.00 148.24 ? 405  LEU A N   1 
ATOM   2350 C  CA  . LEU A 1 405 ? 174.981 182.529 96.246  1.00 148.24 ? 405  LEU A CA  1 
ATOM   2351 C  C   . LEU A 1 405 ? 174.075 181.399 96.714  1.00 148.24 ? 405  LEU A C   1 
ATOM   2352 O  O   . LEU A 1 405 ? 172.845 181.523 96.676  1.00 148.24 ? 405  LEU A O   1 
ATOM   2353 C  CB  . LEU A 1 405 ? 175.453 182.281 94.813  1.00 148.24 ? 405  LEU A CB  1 
ATOM   2354 C  CG  . LEU A 1 405 ? 176.653 183.108 94.349  1.00 148.24 ? 405  LEU A CG  1 
ATOM   2355 C  CD1 . LEU A 1 405 ? 177.103 182.677 92.963  1.00 148.24 ? 405  LEU A CD1 1 
ATOM   2356 C  CD2 . LEU A 1 405 ? 176.321 184.592 94.371  1.00 148.24 ? 405  LEU A CD2 1 
ATOM   2357 N  N   . ASN A 1 406 ? 174.665 180.289 97.163  1.00 146.62 ? 406  ASN A N   1 
ATOM   2358 C  CA  . ASN A 1 406 ? 173.863 179.159 97.620  1.00 146.62 ? 406  ASN A CA  1 
ATOM   2359 C  C   . ASN A 1 406 ? 172.999 179.543 98.813  1.00 146.62 ? 406  ASN A C   1 
ATOM   2360 O  O   . ASN A 1 406 ? 171.829 179.151 98.895  1.00 146.62 ? 406  ASN A O   1 
ATOM   2361 C  CB  . ASN A 1 406 ? 174.770 177.981 97.974  1.00 146.62 ? 406  ASN A CB  1 
ATOM   2362 N  N   . SER A 1 407 ? 173.558 180.310 99.750  1.00 144.65 ? 407  SER A N   1 
ATOM   2363 C  CA  . SER A 1 407 ? 172.788 180.724 100.917 1.00 144.65 ? 407  SER A CA  1 
ATOM   2364 C  C   . SER A 1 407 ? 171.734 181.761 100.550 1.00 144.65 ? 407  SER A C   1 
ATOM   2365 O  O   . SER A 1 407 ? 170.597 181.698 101.032 1.00 144.65 ? 407  SER A O   1 
ATOM   2366 C  CB  . SER A 1 407 ? 173.725 181.273 101.991 1.00 144.65 ? 407  SER A CB  1 
ATOM   2367 O  OG  . SER A 1 407 ? 174.625 182.218 101.441 1.00 144.65 ? 407  SER A OG  1 
ATOM   2368 N  N   . HIS A 1 408 ? 172.090 182.723 99.696  1.00 146.42 ? 408  HIS A N   1 
ATOM   2369 C  CA  . HIS A 1 408 ? 171.185 183.836 99.425  1.00 146.42 ? 408  HIS A CA  1 
ATOM   2370 C  C   . HIS A 1 408 ? 170.024 183.418 98.532  1.00 146.42 ? 408  HIS A C   1 
ATOM   2371 O  O   . HIS A 1 408 ? 168.876 183.806 98.779  1.00 146.42 ? 408  HIS A O   1 
ATOM   2372 C  CB  . HIS A 1 408 ? 171.957 184.991 98.793  1.00 146.42 ? 408  HIS A CB  1 
ATOM   2373 C  CG  . HIS A 1 408 ? 171.114 185.886 97.940  1.00 146.42 ? 408  HIS A CG  1 
ATOM   2374 N  ND1 . HIS A 1 408 ? 170.400 186.947 98.454  1.00 146.42 ? 408  HIS A ND1 1 
ATOM   2375 C  CD2 . HIS A 1 408 ? 170.878 185.885 96.606  1.00 146.42 ? 408  HIS A CD2 1 
ATOM   2376 C  CE1 . HIS A 1 408 ? 169.756 187.557 97.475  1.00 146.42 ? 408  HIS A CE1 1 
ATOM   2377 N  NE2 . HIS A 1 408 ? 170.029 186.932 96.344  1.00 146.42 ? 408  HIS A NE2 1 
ATOM   2378 N  N   . TYR A 1 409 ? 170.296 182.631 97.494  1.00 148.16 ? 409  TYR A N   1 
ATOM   2379 C  CA  . TYR A 1 409 ? 169.283 182.275 96.510  1.00 148.16 ? 409  TYR A CA  1 
ATOM   2380 C  C   . TYR A 1 409 ? 168.443 181.075 96.923  1.00 148.16 ? 409  TYR A C   1 
ATOM   2381 O  O   . TYR A 1 409 ? 167.836 180.435 96.055  1.00 148.16 ? 409  TYR A O   1 
ATOM   2382 C  CB  . TYR A 1 409 ? 169.941 182.009 95.154  1.00 148.16 ? 409  TYR A CB  1 
ATOM   2383 N  N   . GLN A 1 410 ? 168.389 180.749 98.210  1.00 147.54 ? 410  GLN A N   1 
ATOM   2384 C  CA  . GLN A 1 410 ? 167.584 179.639 98.699  1.00 147.54 ? 410  GLN A CA  1 
ATOM   2385 C  C   . GLN A 1 410 ? 166.245 180.168 99.197  1.00 147.54 ? 410  GLN A C   1 
ATOM   2386 O  O   . GLN A 1 410 ? 166.180 181.243 99.805  1.00 147.54 ? 410  GLN A O   1 
ATOM   2387 C  CB  . GLN A 1 410 ? 168.318 178.870 99.803  1.00 147.54 ? 410  GLN A CB  1 
ATOM   2388 C  CG  . GLN A 1 410 ? 168.198 179.448 101.208 1.00 147.54 ? 410  GLN A CG  1 
ATOM   2389 C  CD  . GLN A 1 410 ? 167.048 178.844 101.994 1.00 147.54 ? 410  GLN A CD  1 
ATOM   2390 O  OE1 . GLN A 1 410 ? 166.995 177.633 102.208 1.00 147.54 ? 410  GLN A OE1 1 
ATOM   2391 N  NE2 . GLN A 1 410 ? 166.119 179.689 102.427 1.00 147.54 ? 410  GLN A NE2 1 
ATOM   2392 N  N   . THR A 1 411 ? 165.177 179.431 98.903  1.00 148.63 ? 411  THR A N   1 
ATOM   2393 C  CA  . THR A 1 411 ? 163.833 179.781 99.339  1.00 148.63 ? 411  THR A CA  1 
ATOM   2394 C  C   . THR A 1 411 ? 163.284 178.807 100.373 1.00 148.63 ? 411  THR A C   1 
ATOM   2395 O  O   . THR A 1 411 ? 162.096 178.873 100.703 1.00 148.63 ? 411  THR A O   1 
ATOM   2396 C  CB  . THR A 1 411 ? 162.887 179.852 98.139  1.00 148.63 ? 411  THR A CB  1 
ATOM   2397 O  OG1 . THR A 1 411 ? 163.015 178.658 97.356  1.00 148.63 ? 411  THR A OG1 1 
ATOM   2398 C  CG2 . THR A 1 411 ? 163.219 181.058 97.272  1.00 148.63 ? 411  THR A CG2 1 
ATOM   2399 N  N   . GLY A 1 412 ? 164.117 177.911 100.892 1.00 145.86 ? 412  GLY A N   1 
ATOM   2400 C  CA  . GLY A 1 412 ? 163.676 176.913 101.839 1.00 145.86 ? 412  GLY A CA  1 
ATOM   2401 C  C   . GLY A 1 412 ? 163.564 177.464 103.247 1.00 145.86 ? 412  GLY A C   1 
ATOM   2402 O  O   . GLY A 1 412 ? 163.474 178.671 103.479 1.00 145.86 ? 412  GLY A O   1 
ATOM   2403 N  N   . LEU A 1 413 ? 163.566 176.541 104.207 1.00 142.59 ? 413  LEU A N   1 
ATOM   2404 C  CA  . LEU A 1 413 ? 163.463 176.915 105.610 1.00 142.59 ? 413  LEU A CA  1 
ATOM   2405 C  C   . LEU A 1 413 ? 164.658 177.760 106.028 1.00 142.59 ? 413  LEU A C   1 
ATOM   2406 O  O   . LEU A 1 413 ? 165.775 177.568 105.541 1.00 142.59 ? 413  LEU A O   1 
ATOM   2407 C  CB  . LEU A 1 413 ? 163.370 175.664 106.487 1.00 142.59 ? 413  LEU A CB  1 
ATOM   2408 C  CG  . LEU A 1 413 ? 161.995 175.005 106.593 1.00 142.59 ? 413  LEU A CG  1 
ATOM   2409 C  CD1 . LEU A 1 413 ? 162.031 173.850 107.582 1.00 142.59 ? 413  LEU A CD1 1 
ATOM   2410 C  CD2 . LEU A 1 413 ? 160.939 176.025 106.992 1.00 142.59 ? 413  LEU A CD2 1 
ATOM   2411 N  N   . LYS A 1 414 ? 164.410 178.710 106.926 1.00 136.35 ? 414  LYS A N   1 
ATOM   2412 C  CA  . LYS A 1 414 ? 165.475 179.575 107.413 1.00 136.35 ? 414  LYS A CA  1 
ATOM   2413 C  C   . LYS A 1 414 ? 166.551 178.748 108.104 1.00 136.35 ? 414  LYS A C   1 
ATOM   2414 O  O   . LYS A 1 414 ? 166.256 177.918 108.968 1.00 136.35 ? 414  LYS A O   1 
ATOM   2415 C  CB  . LYS A 1 414 ? 164.905 180.615 108.377 1.00 136.35 ? 414  LYS A CB  1 
ATOM   2416 C  CG  . LYS A 1 414 ? 165.908 181.657 108.838 1.00 136.35 ? 414  LYS A CG  1 
ATOM   2417 C  CD  . LYS A 1 414 ? 166.090 182.748 107.796 1.00 136.35 ? 414  LYS A CD  1 
ATOM   2418 C  CE  . LYS A 1 414 ? 166.533 184.053 108.436 1.00 136.35 ? 414  LYS A CE  1 
ATOM   2419 N  NZ  . LYS A 1 414 ? 166.423 185.200 107.494 1.00 136.35 ? 414  LYS A NZ  1 
ATOM   2420 N  N   . ASN A 1 415 ? 167.803 178.982 107.722 1.00 131.93 ? 415  ASN A N   1 
ATOM   2421 C  CA  . ASN A 1 415 ? 168.944 178.260 108.267 1.00 131.93 ? 415  ASN A CA  1 
ATOM   2422 C  C   . ASN A 1 415 ? 169.855 179.247 108.979 1.00 131.93 ? 415  ASN A C   1 
ATOM   2423 O  O   . ASN A 1 415 ? 170.205 180.291 108.419 1.00 131.93 ? 415  ASN A O   1 
ATOM   2424 C  CB  . ASN A 1 415 ? 169.711 177.523 107.164 1.00 131.93 ? 415  ASN A CB  1 
ATOM   2425 C  CG  . ASN A 1 415 ? 170.982 176.865 107.671 1.00 131.93 ? 415  ASN A CG  1 
ATOM   2426 O  OD1 . ASN A 1 415 ? 171.141 176.629 108.869 1.00 131.93 ? 415  ASN A OD1 1 
ATOM   2427 N  ND2 . ASN A 1 415 ? 171.896 176.565 106.755 1.00 131.93 ? 415  ASN A ND2 1 
ATOM   2428 N  N   . LEU A 1 416 ? 170.232 178.917 110.216 1.00 124.33 ? 416  LEU A N   1 
ATOM   2429 C  CA  . LEU A 1 416 ? 171.124 179.793 110.965 1.00 124.33 ? 416  LEU A CA  1 
ATOM   2430 C  C   . LEU A 1 416 ? 172.518 179.794 110.350 1.00 124.33 ? 416  LEU A C   1 
ATOM   2431 O  O   . LEU A 1 416 ? 173.196 180.828 110.325 1.00 124.33 ? 416  LEU A O   1 
ATOM   2432 C  CB  . LEU A 1 416 ? 171.158 179.364 112.433 1.00 124.33 ? 416  LEU A CB  1 
ATOM   2433 C  CG  . LEU A 1 416 ? 172.288 179.810 113.362 1.00 124.33 ? 416  LEU A CG  1 
ATOM   2434 C  CD1 . LEU A 1 416 ? 172.470 181.321 113.353 1.00 124.33 ? 416  LEU A CD1 1 
ATOM   2435 C  CD2 . LEU A 1 416 ? 172.017 179.322 114.775 1.00 124.33 ? 416  LEU A CD2 1 
ATOM   2436 N  N   . LEU A 1 417 ? 172.954 178.645 109.828 1.00 123.53 ? 417  LEU A N   1 
ATOM   2437 C  CA  . LEU A 1 417 ? 174.230 178.582 109.121 1.00 123.53 ? 417  LEU A CA  1 
ATOM   2438 C  C   . LEU A 1 417 ? 174.212 179.457 107.875 1.00 123.53 ? 417  LEU A C   1 
ATOM   2439 O  O   . LEU A 1 417 ? 175.208 180.120 107.550 1.00 123.53 ? 417  LEU A O   1 
ATOM   2440 C  CB  . LEU A 1 417 ? 174.551 177.135 108.750 1.00 123.53 ? 417  LEU A CB  1 
ATOM   2441 C  CG  . LEU A 1 417 ? 175.320 176.300 109.776 1.00 123.53 ? 417  LEU A CG  1 
ATOM   2442 C  CD1 . LEU A 1 417 ? 176.722 176.845 109.938 1.00 123.53 ? 417  LEU A CD1 1 
ATOM   2443 C  CD2 . LEU A 1 417 ? 174.608 176.245 111.118 1.00 123.53 ? 417  LEU A CD2 1 
ATOM   2444 N  N   . ASP A 1 418 ? 173.091 179.451 107.150 1.00 130.85 ? 418  ASP A N   1 
ATOM   2445 C  CA  . ASP A 1 418 ? 172.972 180.291 105.965 1.00 130.85 ? 418  ASP A CA  1 
ATOM   2446 C  C   . ASP A 1 418 ? 173.047 181.766 106.330 1.00 130.85 ? 418  ASP A C   1 
ATOM   2447 O  O   . ASP A 1 418 ? 173.692 182.551 105.630 1.00 130.85 ? 418  ASP A O   1 
ATOM   2448 C  CB  . ASP A 1 418 ? 171.672 179.978 105.227 1.00 130.85 ? 418  ASP A CB  1 
ATOM   2449 C  CG  . ASP A 1 418 ? 171.778 178.730 104.375 1.00 130.85 ? 418  ASP A CG  1 
ATOM   2450 O  OD1 . ASP A 1 418 ? 172.427 177.762 104.820 1.00 130.85 ? 418  ASP A OD1 1 
ATOM   2451 O  OD2 . ASP A 1 418 ? 171.221 178.720 103.257 1.00 130.85 ? 418  ASP A OD2 1 
ATOM   2452 N  N   . THR A 1 419 ? 172.405 182.163 107.429 1.00 128.60 ? 419  THR A N   1 
ATOM   2453 C  CA  . THR A 1 419 ? 172.523 183.547 107.876 1.00 128.60 ? 419  THR A CA  1 
ATOM   2454 C  C   . THR A 1 419 ? 173.950 183.867 108.305 1.00 128.60 ? 419  THR A C   1 
ATOM   2455 O  O   . THR A 1 419 ? 174.427 184.989 108.104 1.00 128.60 ? 419  THR A O   1 
ATOM   2456 C  CB  . THR A 1 419 ? 171.547 183.825 109.016 1.00 128.60 ? 419  THR A CB  1 
ATOM   2457 O  OG1 . THR A 1 419 ? 171.512 182.701 109.901 1.00 128.60 ? 419  THR A OG1 1 
ATOM   2458 C  CG2 . THR A 1 419 ? 170.153 184.073 108.470 1.00 128.60 ? 419  THR A CG2 1 
ATOM   2459 N  N   . ALA A 1 420 ? 174.647 182.895 108.896 1.00 127.58 ? 420  ALA A N   1 
ATOM   2460 C  CA  . ALA A 1 420 ? 176.033 183.116 109.294 1.00 127.58 ? 420  ALA A CA  1 
ATOM   2461 C  C   . ALA A 1 420 ? 176.915 183.393 108.082 1.00 127.58 ? 420  ALA A C   1 
ATOM   2462 O  O   . ALA A 1 420 ? 177.673 184.371 108.057 1.00 127.58 ? 420  ALA A O   1 
ATOM   2463 C  CB  . ALA A 1 420 ? 176.550 181.908 110.074 1.00 127.58 ? 420  ALA A CB  1 
ATOM   2464 N  N   . VAL A 1 421 ? 176.821 182.543 107.058 1.00 130.06 ? 421  VAL A N   1 
ATOM   2465 C  CA  . VAL A 1 421 ? 177.638 182.758 105.866 1.00 130.06 ? 421  VAL A CA  1 
ATOM   2466 C  C   . VAL A 1 421 ? 177.187 184.019 105.133 1.00 130.06 ? 421  VAL A C   1 
ATOM   2467 O  O   . VAL A 1 421 ? 177.998 184.714 104.509 1.00 130.06 ? 421  VAL A O   1 
ATOM   2468 C  CB  . VAL A 1 421 ? 177.623 181.516 104.953 1.00 130.06 ? 421  VAL A CB  1 
ATOM   2469 C  CG1 . VAL A 1 421 ? 176.213 181.088 104.635 1.00 130.06 ? 421  VAL A CG1 1 
ATOM   2470 C  CG2 . VAL A 1 421 ? 178.410 181.771 103.675 1.00 130.06 ? 421  VAL A CG2 1 
ATOM   2471 N  N   . LEU A 1 422 ? 175.893 184.348 105.215 1.00 132.82 ? 422  LEU A N   1 
ATOM   2472 C  CA  . LEU A 1 422 ? 175.396 185.600 104.656 1.00 132.82 ? 422  LEU A CA  1 
ATOM   2473 C  C   . LEU A 1 422 ? 176.045 186.804 105.320 1.00 132.82 ? 422  LEU A C   1 
ATOM   2474 O  O   . LEU A 1 422 ? 176.449 187.753 104.638 1.00 132.82 ? 422  LEU A O   1 
ATOM   2475 C  CB  . LEU A 1 422 ? 173.877 185.666 104.825 1.00 132.82 ? 422  LEU A CB  1 
ATOM   2476 C  CG  . LEU A 1 422 ? 173.056 186.591 103.926 1.00 132.82 ? 422  LEU A CG  1 
ATOM   2477 C  CD1 . LEU A 1 422 ? 173.526 186.504 102.489 1.00 132.82 ? 422  LEU A CD1 1 
ATOM   2478 C  CD2 . LEU A 1 422 ? 171.576 186.259 104.030 1.00 132.82 ? 422  LEU A CD2 1 
ATOM   2479 N  N   . GLU A 1 423 ? 176.148 186.783 106.648 1.00 131.52 ? 423  GLU A N   1 
ATOM   2480 C  CA  . GLU A 1 423 ? 176.802 187.860 107.379 1.00 131.52 ? 423  GLU A CA  1 
ATOM   2481 C  C   . GLU A 1 423 ? 178.304 187.880 107.129 1.00 131.52 ? 423  GLU A C   1 
ATOM   2482 O  O   . GLU A 1 423 ? 178.930 188.942 107.227 1.00 131.52 ? 423  GLU A O   1 
ATOM   2483 C  CB  . GLU A 1 423 ? 176.502 187.721 108.875 1.00 131.52 ? 423  GLU A CB  1 
ATOM   2484 C  CG  . GLU A 1 423 ? 177.138 188.775 109.774 1.00 131.52 ? 423  GLU A CG  1 
ATOM   2485 C  CD  . GLU A 1 423 ? 178.536 188.397 110.227 1.00 131.52 ? 423  GLU A CD  1 
ATOM   2486 O  OE1 . GLU A 1 423 ? 178.718 187.257 110.704 1.00 131.52 ? 423  GLU A OE1 1 
ATOM   2487 O  OE2 . GLU A 1 423 ? 179.450 189.238 110.105 1.00 131.52 ? 423  GLU A OE2 1 
ATOM   2488 N  N   . GLY A 1 424 ? 178.891 186.729 106.798 1.00 133.80 ? 424  GLY A N   1 
ATOM   2489 C  CA  . GLY A 1 424 ? 180.334 186.670 106.617 1.00 133.80 ? 424  GLY A CA  1 
ATOM   2490 C  C   . GLY A 1 424 ? 180.838 187.569 105.505 1.00 133.80 ? 424  GLY A C   1 
ATOM   2491 O  O   . GLY A 1 424 ? 181.931 188.133 105.592 1.00 133.80 ? 424  GLY A O   1 
ATOM   2492 N  N   . THR A 1 425 ? 180.051 187.717 104.444 1.00 140.87 ? 425  THR A N   1 
ATOM   2493 C  CA  . THR A 1 425 ? 180.470 188.444 103.254 1.00 140.87 ? 425  THR A CA  1 
ATOM   2494 C  C   . THR A 1 425 ? 180.201 189.940 103.388 1.00 140.87 ? 425  THR A C   1 
ATOM   2495 O  O   . THR A 1 425 ? 179.356 190.382 104.171 1.00 140.87 ? 425  THR A O   1 
ATOM   2496 C  CB  . THR A 1 425 ? 179.760 187.902 102.011 1.00 140.87 ? 425  THR A CB  1 
ATOM   2497 N  N   . ASP A 1 426 ? 180.941 190.719 102.597 1.00 150.88 ? 426  ASP A N   1 
ATOM   2498 C  CA  . ASP A 1 426 ? 180.807 192.170 102.617 1.00 150.88 ? 426  ASP A CA  1 
ATOM   2499 C  C   . ASP A 1 426 ? 179.523 192.601 101.919 1.00 150.88 ? 426  ASP A C   1 
ATOM   2500 O  O   . ASP A 1 426 ? 178.924 191.846 101.148 1.00 150.88 ? 426  ASP A O   1 
ATOM   2501 C  CB  . ASP A 1 426 ? 182.016 192.825 101.946 1.00 150.88 ? 426  ASP A CB  1 
ATOM   2502 N  N   . GLU A 1 427 ? 179.104 193.838 102.194 1.00 153.19 ? 427  GLU A N   1 
ATOM   2503 C  CA  . GLU A 1 427 ? 177.835 194.331 101.665 1.00 153.19 ? 427  GLU A CA  1 
ATOM   2504 C  C   . GLU A 1 427 ? 177.935 194.653 100.177 1.00 153.19 ? 427  GLU A C   1 
ATOM   2505 O  O   . GLU A 1 427 ? 177.022 194.340 99.404  1.00 153.19 ? 427  GLU A O   1 
ATOM   2506 C  CB  . GLU A 1 427 ? 177.385 195.562 102.452 1.00 153.19 ? 427  GLU A CB  1 
ATOM   2507 N  N   . GLU A 1 428 ? 179.029 195.293 99.759  1.00 153.53 ? 428  GLU A N   1 
ATOM   2508 C  CA  . GLU A 1 428 ? 179.167 195.689 98.359  1.00 153.53 ? 428  GLU A CA  1 
ATOM   2509 C  C   . GLU A 1 428 ? 179.244 194.470 97.448  1.00 153.53 ? 428  GLU A C   1 
ATOM   2510 O  O   . GLU A 1 428 ? 178.581 194.413 96.404  1.00 153.53 ? 428  GLU A O   1 
ATOM   2511 C  CB  . GLU A 1 428 ? 180.401 196.574 98.185  1.00 153.53 ? 428  GLU A CB  1 
ATOM   2512 N  N   . SER A 1 429 ? 180.055 193.481 97.830  1.00 154.77 ? 429  SER A N   1 
ATOM   2513 C  CA  . SER A 1 429 ? 180.146 192.255 97.044  1.00 154.77 ? 429  SER A CA  1 
ATOM   2514 C  C   . SER A 1 429 ? 178.817 191.515 97.036  1.00 154.77 ? 429  SER A C   1 
ATOM   2515 O  O   . SER A 1 429 ? 178.429 190.929 96.019  1.00 154.77 ? 429  SER A O   1 
ATOM   2516 C  CB  . SER A 1 429 ? 181.258 191.361 97.592  1.00 154.77 ? 429  SER A CB  1 
ATOM   2517 N  N   . ALA A 1 430 ? 178.104 191.530 98.165  1.00 156.30 ? 430  ALA A N   1 
ATOM   2518 C  CA  . ALA A 1 430 ? 176.792 190.896 98.222  1.00 156.30 ? 430  ALA A CA  1 
ATOM   2519 C  C   . ALA A 1 430 ? 175.818 191.554 97.254  1.00 156.30 ? 430  ALA A C   1 
ATOM   2520 O  O   . ALA A 1 430 ? 175.087 190.866 96.533  1.00 156.30 ? 430  ALA A O   1 
ATOM   2521 C  CB  . ALA A 1 430 ? 176.247 190.951 99.649  1.00 156.30 ? 430  ALA A CB  1 
ATOM   2522 N  N   . ARG A 1 431 ? 175.798 192.888 97.222  1.00 158.91 ? 431  ARG A N   1 
ATOM   2523 C  CA  . ARG A 1 431 ? 174.913 193.595 96.302  1.00 158.91 ? 431  ARG A CA  1 
ATOM   2524 C  C   . ARG A 1 431 ? 175.293 193.320 94.853  1.00 158.91 ? 431  ARG A C   1 
ATOM   2525 O  O   . ARG A 1 431 ? 174.419 193.124 93.999  1.00 158.91 ? 431  ARG A O   1 
ATOM   2526 C  CB  . ARG A 1 431 ? 174.945 195.095 96.591  1.00 158.91 ? 431  ARG A CB  1 
ATOM   2527 N  N   . SER A 1 432 ? 176.596 193.302 94.556  1.00 159.16 ? 432  SER A N   1 
ATOM   2528 C  CA  . SER A 1 432 ? 177.035 193.015 93.194  1.00 159.16 ? 432  SER A CA  1 
ATOM   2529 C  C   . SER A 1 432 ? 176.624 191.611 92.767  1.00 159.16 ? 432  SER A C   1 
ATOM   2530 O  O   . SER A 1 432 ? 176.148 191.409 91.644  1.00 159.16 ? 432  SER A O   1 
ATOM   2531 C  CB  . SER A 1 432 ? 178.550 193.189 93.084  1.00 159.16 ? 432  SER A CB  1 
ATOM   2532 N  N   . LEU A 1 433 ? 176.794 190.628 93.655  1.00 160.00 ? 433  LEU A N   1 
ATOM   2533 C  CA  . LEU A 1 433 ? 176.397 189.261 93.337  1.00 160.00 ? 433  LEU A CA  1 
ATOM   2534 C  C   . LEU A 1 433 ? 174.889 189.150 93.155  1.00 160.00 ? 433  LEU A C   1 
ATOM   2535 O  O   . LEU A 1 433 ? 174.417 188.451 92.251  1.00 160.00 ? 433  LEU A O   1 
ATOM   2536 C  CB  . LEU A 1 433 ? 176.878 188.308 94.431  1.00 160.00 ? 433  LEU A CB  1 
ATOM   2537 N  N   . ALA A 1 434 ? 174.116 189.827 94.009  1.00 160.89 ? 434  ALA A N   1 
ATOM   2538 C  CA  . ALA A 1 434 ? 172.663 189.788 93.882  1.00 160.89 ? 434  ALA A CA  1 
ATOM   2539 C  C   . ALA A 1 434 ? 172.209 190.403 92.566  1.00 160.89 ? 434  ALA A C   1 
ATOM   2540 O  O   . ALA A 1 434 ? 171.294 189.887 91.913  1.00 160.89 ? 434  ALA A O   1 
ATOM   2541 C  CB  . ALA A 1 434 ? 172.014 190.506 95.065  1.00 160.89 ? 434  ALA A CB  1 
ATOM   2542 N  N   . SER A 1 435 ? 172.832 191.511 92.160  1.00 161.22 ? 435  SER A N   1 
ATOM   2543 C  CA  . SER A 1 435 ? 172.479 192.127 90.887  1.00 161.22 ? 435  SER A CA  1 
ATOM   2544 C  C   . SER A 1 435 ? 172.904 191.266 89.705  1.00 161.22 ? 435  SER A C   1 
ATOM   2545 O  O   . SER A 1 435 ? 172.199 191.217 88.690  1.00 161.22 ? 435  SER A O   1 
ATOM   2546 C  CB  . SER A 1 435 ? 173.108 193.517 90.784  1.00 161.22 ? 435  SER A CB  1 
ATOM   2547 N  N   . ARG A 1 436 ? 174.044 190.581 89.814  1.00 162.20 ? 436  ARG A N   1 
ATOM   2548 C  CA  . ARG A 1 436 ? 174.565 189.812 88.689  1.00 162.20 ? 436  ARG A CA  1 
ATOM   2549 C  C   . ARG A 1 436 ? 173.818 188.500 88.476  1.00 162.20 ? 436  ARG A C   1 
ATOM   2550 O  O   . ARG A 1 436 ? 173.656 188.066 87.330  1.00 162.20 ? 436  ARG A O   1 
ATOM   2551 C  CB  . ARG A 1 436 ? 176.055 189.535 88.894  1.00 162.20 ? 436  ARG A CB  1 
ATOM   2552 C  CG  . ARG A 1 436 ? 176.730 188.843 87.723  1.00 162.20 ? 436  ARG A CG  1 
ATOM   2553 C  CD  . ARG A 1 436 ? 178.242 188.942 87.823  1.00 162.20 ? 436  ARG A CD  1 
ATOM   2554 N  NE  . ARG A 1 436 ? 178.906 188.291 86.701  1.00 162.20 ? 436  ARG A NE  1 
ATOM   2555 C  CZ  . ARG A 1 436 ? 179.438 187.077 86.748  1.00 162.20 ? 436  ARG A CZ  1 
ATOM   2556 N  NH1 . ARG A 1 436 ? 179.409 186.352 87.854  1.00 162.20 ? 436  ARG A NH1 1 
ATOM   2557 N  NH2 . ARG A 1 436 ? 180.016 186.579 85.658  1.00 162.20 ? 436  ARG A NH2 1 
ATOM   2558 N  N   . TRP A 1 437 ? 173.353 187.863 89.547  1.00 163.96 ? 437  TRP A N   1 
ATOM   2559 C  CA  . TRP A 1 437 ? 172.775 186.530 89.471  1.00 163.96 ? 437  TRP A CA  1 
ATOM   2560 C  C   . TRP A 1 437 ? 171.307 186.554 89.871  1.00 163.96 ? 437  TRP A C   1 
ATOM   2561 O  O   . TRP A 1 437 ? 170.875 187.385 90.675  1.00 163.96 ? 437  TRP A O   1 
ATOM   2562 C  CB  . TRP A 1 437 ? 173.536 185.550 90.369  1.00 163.96 ? 437  TRP A CB  1 
ATOM   2563 C  CG  . TRP A 1 437 ? 174.929 185.278 89.904  1.00 163.96 ? 437  TRP A CG  1 
ATOM   2564 C  CD1 . TRP A 1 437 ? 176.049 185.995 90.207  1.00 163.96 ? 437  TRP A CD1 1 
ATOM   2565 C  CD2 . TRP A 1 437 ? 175.357 184.201 89.063  1.00 163.96 ? 437  TRP A CD2 1 
ATOM   2566 N  NE1 . TRP A 1 437 ? 177.147 185.436 89.599  1.00 163.96 ? 437  TRP A NE1 1 
ATOM   2567 C  CE2 . TRP A 1 437 ? 176.749 184.333 88.892  1.00 163.96 ? 437  TRP A CE2 1 
ATOM   2568 C  CE3 . TRP A 1 437 ? 174.698 183.140 88.436  1.00 163.96 ? 437  TRP A CE3 1 
ATOM   2569 C  CZ2 . TRP A 1 437 ? 177.493 183.445 88.120  1.00 163.96 ? 437  TRP A CZ2 1 
ATOM   2570 C  CZ3 . TRP A 1 437 ? 175.438 182.259 87.670  1.00 163.96 ? 437  TRP A CZ3 1 
ATOM   2571 C  CH2 . TRP A 1 437 ? 176.820 182.417 87.518  1.00 163.96 ? 437  TRP A CH2 1 
ATOM   2572 N  N   . GLN A 1 438 ? 170.543 185.628 89.297  1.00 165.58 ? 438  GLN A N   1 
ATOM   2573 C  CA  . GLN A 1 438 ? 169.136 185.455 89.616  1.00 165.58 ? 438  GLN A CA  1 
ATOM   2574 C  C   . GLN A 1 438 ? 168.856 183.985 89.887  1.00 165.58 ? 438  GLN A C   1 
ATOM   2575 O  O   . GLN A 1 438 ? 169.438 183.099 89.255  1.00 165.58 ? 438  GLN A O   1 
ATOM   2576 C  CB  . GLN A 1 438 ? 168.233 185.960 88.482  1.00 165.58 ? 438  GLN A CB  1 
ATOM   2577 N  N   . LYS A 1 439 ? 167.958 183.734 90.834  1.00 167.12 ? 439  LYS A N   1 
ATOM   2578 C  CA  . LYS A 1 439 ? 167.605 182.372 91.202  1.00 167.12 ? 439  LYS A CA  1 
ATOM   2579 C  C   . LYS A 1 439 ? 166.814 181.700 90.086  1.00 167.12 ? 439  LYS A C   1 
ATOM   2580 O  O   . LYS A 1 439 ? 165.989 182.325 89.414  1.00 167.12 ? 439  LYS A O   1 
ATOM   2581 C  CB  . LYS A 1 439 ? 166.795 182.358 92.498  1.00 167.12 ? 439  LYS A CB  1 
ATOM   2582 N  N   . ILE A 1 440 ? 167.075 180.406 89.895  1.00 168.58 ? 440  ILE A N   1 
ATOM   2583 C  CA  . ILE A 1 440 ? 166.402 179.599 88.885  1.00 168.58 ? 440  ILE A CA  1 
ATOM   2584 C  C   . ILE A 1 440 ? 165.669 178.419 89.513  1.00 168.58 ? 440  ILE A C   1 
ATOM   2585 O  O   . ILE A 1 440 ? 164.456 178.262 89.338  1.00 168.58 ? 440  ILE A O   1 
ATOM   2586 C  CB  . ILE A 1 440 ? 167.391 179.112 87.802  1.00 168.58 ? 440  ILE A CB  1 
ATOM   2587 N  N   . ASP A 1 441 ? 166.390 177.577 90.248  1.00 169.26 ? 441  ASP A N   1 
ATOM   2588 C  CA  . ASP A 1 441 ? 165.788 176.425 90.902  1.00 169.26 ? 441  ASP A CA  1 
ATOM   2589 C  C   . ASP A 1 441 ? 166.574 176.103 92.164  1.00 169.26 ? 441  ASP A C   1 
ATOM   2590 O  O   . ASP A 1 441 ? 167.740 176.482 92.307  1.00 169.26 ? 441  ASP A O   1 
ATOM   2591 C  CB  . ASP A 1 441 ? 165.743 175.207 89.971  1.00 169.26 ? 441  ASP A CB  1 
ATOM   2592 N  N   . GLU A 1 442 ? 165.919 175.396 93.081  1.00 168.49 ? 442  GLU A N   1 
ATOM   2593 C  CA  . GLU A 1 442 ? 166.529 175.012 94.345  1.00 168.49 ? 442  GLU A CA  1 
ATOM   2594 C  C   . GLU A 1 442 ? 166.218 173.553 94.637  1.00 168.49 ? 442  GLU A C   1 
ATOM   2595 O  O   . GLU A 1 442 ? 165.105 173.084 94.383  1.00 168.49 ? 442  GLU A O   1 
ATOM   2596 C  CB  . GLU A 1 442 ? 166.033 175.895 95.498  1.00 168.49 ? 442  GLU A CB  1 
ATOM   2597 N  N   . ILE A 1 443 ? 167.204 172.843 95.172  1.00 169.18 ? 443  ILE A N   1 
ATOM   2598 C  CA  . ILE A 1 443 ? 167.067 171.444 95.557  1.00 169.18 ? 443  ILE A CA  1 
ATOM   2599 C  C   . ILE A 1 443 ? 166.914 171.396 97.076  1.00 169.18 ? 443  ILE A C   1 
ATOM   2600 O  O   . ILE A 1 443 ? 167.855 171.747 97.804  1.00 169.18 ? 443  ILE A O   1 
ATOM   2601 C  CB  . ILE A 1 443 ? 168.265 170.605 95.092  1.00 169.18 ? 443  ILE A CB  1 
ATOM   2602 N  N   . PRO A 1 444 ? 165.759 170.987 97.597  1.00 170.39 ? 444  PRO A N   1 
ATOM   2603 C  CA  . PRO A 1 444 ? 165.576 170.944 99.052  1.00 170.39 ? 444  PRO A CA  1 
ATOM   2604 C  C   . PRO A 1 444 ? 166.531 169.963 99.714  1.00 170.39 ? 444  PRO A C   1 
ATOM   2605 O  O   . PRO A 1 444 ? 166.917 168.938 99.148  1.00 170.39 ? 444  PRO A O   1 
ATOM   2606 C  CB  . PRO A 1 444 ? 164.120 170.492 99.212  1.00 170.39 ? 444  PRO A CB  1 
ATOM   2607 C  CG  . PRO A 1 444 ? 163.467 170.866 97.917  1.00 170.39 ? 444  PRO A CG  1 
ATOM   2608 C  CD  . PRO A 1 444 ? 164.524 170.637 96.879  1.00 170.39 ? 444  PRO A CD  1 
ATOM   2609 N  N   . PHE A 1 445 ? 166.915 170.302 100.942 1.00 171.56 ? 445  PHE A N   1 
ATOM   2610 C  CA  . PHE A 1 445 ? 167.815 169.453 101.708 1.00 171.56 ? 445  PHE A CA  1 
ATOM   2611 C  C   . PHE A 1 445 ? 167.097 168.183 102.146 1.00 171.56 ? 445  PHE A C   1 
ATOM   2612 O  O   . PHE A 1 445 ? 165.971 168.235 102.651 1.00 171.56 ? 445  PHE A O   1 
ATOM   2613 C  CB  . PHE A 1 445 ? 168.348 170.212 102.923 1.00 171.56 ? 445  PHE A CB  1 
ATOM   2614 C  CG  . PHE A 1 445 ? 169.120 169.355 103.885 1.00 171.56 ? 445  PHE A CG  1 
ATOM   2615 C  CD1 . PHE A 1 445 ? 170.459 169.080 103.664 1.00 171.56 ? 445  PHE A CD1 1 
ATOM   2616 C  CD2 . PHE A 1 445 ? 168.512 168.837 105.017 1.00 171.56 ? 445  PHE A CD2 1 
ATOM   2617 C  CE1 . PHE A 1 445 ? 171.174 168.296 104.547 1.00 171.56 ? 445  PHE A CE1 1 
ATOM   2618 C  CE2 . PHE A 1 445 ? 169.222 168.052 105.904 1.00 171.56 ? 445  PHE A CE2 1 
ATOM   2619 C  CZ  . PHE A 1 445 ? 170.555 167.781 105.669 1.00 171.56 ? 445  PHE A CZ  1 
ATOM   2620 N  N   . ASP A 1 446 ? 167.751 167.041 101.952 1.00 174.21 ? 446  ASP A N   1 
ATOM   2621 C  CA  . ASP A 1 446 ? 167.200 165.754 102.344 1.00 174.21 ? 446  ASP A CA  1 
ATOM   2622 C  C   . ASP A 1 446 ? 168.271 164.951 103.066 1.00 174.21 ? 446  ASP A C   1 
ATOM   2623 O  O   . ASP A 1 446 ? 169.462 165.069 102.769 1.00 174.21 ? 446  ASP A O   1 
ATOM   2624 C  CB  . ASP A 1 446 ? 166.677 164.968 101.134 1.00 174.21 ? 446  ASP A CB  1 
ATOM   2625 N  N   . PHE A 1 447 ? 167.832 164.128 104.019 1.00 175.64 ? 447  PHE A N   1 
ATOM   2626 C  CA  . PHE A 1 447 ? 168.760 163.307 104.786 1.00 175.64 ? 447  PHE A CA  1 
ATOM   2627 C  C   . PHE A 1 447 ? 169.384 162.193 103.958 1.00 175.64 ? 447  PHE A C   1 
ATOM   2628 O  O   . PHE A 1 447 ? 170.454 161.694 104.324 1.00 175.64 ? 447  PHE A O   1 
ATOM   2629 C  CB  . PHE A 1 447 ? 168.050 162.708 106.003 1.00 175.64 ? 447  PHE A CB  1 
ATOM   2630 N  N   . GLU A 1 448 ? 168.741 161.789 102.860 1.00 176.78 ? 448  GLU A N   1 
ATOM   2631 C  CA  . GLU A 1 448 ? 169.307 160.743 102.014 1.00 176.78 ? 448  GLU A CA  1 
ATOM   2632 C  C   . GLU A 1 448 ? 170.612 161.196 101.373 1.00 176.78 ? 448  GLU A C   1 
ATOM   2633 O  O   . GLU A 1 448 ? 171.582 160.431 101.312 1.00 176.78 ? 448  GLU A O   1 
ATOM   2634 C  CB  . GLU A 1 448 ? 168.297 160.331 100.943 1.00 176.78 ? 448  GLU A CB  1 
ATOM   2635 N  N   . ARG A 1 449 ? 170.658 162.438 100.891 1.00 174.59 ? 449  ARG A N   1 
ATOM   2636 C  CA  . ARG A 1 449 ? 171.854 162.985 100.269 1.00 174.59 ? 449  ARG A CA  1 
ATOM   2637 C  C   . ARG A 1 449 ? 172.639 163.915 101.182 1.00 174.59 ? 449  ARG A C   1 
ATOM   2638 O  O   . ARG A 1 449 ? 173.819 164.163 100.912 1.00 174.59 ? 449  ARG A O   1 
ATOM   2639 C  CB  . ARG A 1 449 ? 171.488 163.736 98.980  1.00 174.59 ? 449  ARG A CB  1 
ATOM   2640 N  N   . ARG A 1 450 ? 172.019 164.429 102.247 1.00 174.33 ? 450  ARG A N   1 
ATOM   2641 C  CA  . ARG A 1 450 ? 172.680 165.321 103.201 1.00 174.33 ? 450  ARG A CA  1 
ATOM   2642 C  C   . ARG A 1 450 ? 173.293 166.530 102.499 1.00 174.33 ? 450  ARG A C   1 
ATOM   2643 O  O   . ARG A 1 450 ? 174.383 166.991 102.843 1.00 174.33 ? 450  ARG A O   1 
ATOM   2644 C  CB  . ARG A 1 450 ? 173.735 164.570 104.017 1.00 174.33 ? 450  ARG A CB  1 
ATOM   2645 N  N   . ARG A 1 451 ? 172.584 167.049 101.499 1.00 170.26 ? 451  ARG A N   1 
ATOM   2646 C  CA  . ARG A 1 451 ? 173.051 168.197 100.740 1.00 170.26 ? 451  ARG A CA  1 
ATOM   2647 C  C   . ARG A 1 451 ? 171.858 168.942 100.159 1.00 170.26 ? 451  ARG A C   1 
ATOM   2648 O  O   . ARG A 1 451 ? 170.770 168.387 99.993  1.00 170.26 ? 451  ARG A O   1 
ATOM   2649 C  CB  . ARG A 1 451 ? 174.012 167.778 99.618  1.00 170.26 ? 451  ARG A CB  1 
ATOM   2650 N  N   . MET A 1 452 ? 172.081 170.218 99.853  1.00 165.90 ? 452  MET A N   1 
ATOM   2651 C  CA  . MET A 1 452 ? 171.082 171.056 99.207  1.00 165.90 ? 452  MET A CA  1 
ATOM   2652 C  C   . MET A 1 452 ? 171.755 171.860 98.106  1.00 165.90 ? 452  MET A C   1 
ATOM   2653 O  O   . MET A 1 452 ? 172.865 172.370 98.279  1.00 165.90 ? 452  MET A O   1 
ATOM   2654 C  CB  . MET A 1 452 ? 170.395 171.996 100.206 1.00 165.90 ? 452  MET A CB  1 
ATOM   2655 N  N   . SER A 1 453 ? 171.071 171.973 96.971  1.00 166.50 ? 453  SER A N   1 
ATOM   2656 C  CA  . SER A 1 453 ? 171.620 172.634 95.798  1.00 166.50 ? 453  SER A CA  1 
ATOM   2657 C  C   . SER A 1 453 ? 170.704 173.765 95.358  1.00 166.50 ? 453  SER A C   1 
ATOM   2658 O  O   . SER A 1 453 ? 169.479 173.684 95.487  1.00 166.50 ? 453  SER A O   1 
ATOM   2659 C  CB  . SER A 1 453 ? 171.818 171.650 94.637  1.00 166.50 ? 453  SER A CB  1 
ATOM   2660 N  N   . VAL A 1 454 ? 171.315 174.825 94.836  1.00 165.73 ? 454  VAL A N   1 
ATOM   2661 C  CA  . VAL A 1 454 ? 170.597 175.978 94.311  1.00 165.73 ? 454  VAL A CA  1 
ATOM   2662 C  C   . VAL A 1 454 ? 171.104 176.251 92.903  1.00 165.73 ? 454  VAL A C   1 
ATOM   2663 O  O   . VAL A 1 454 ? 172.318 176.320 92.679  1.00 165.73 ? 454  VAL A O   1 
ATOM   2664 C  CB  . VAL A 1 454 ? 170.776 177.222 95.202  1.00 165.73 ? 454  VAL A CB  1 
ATOM   2665 N  N   . VAL A 1 455 ? 170.180 176.404 91.961  1.00 169.22 ? 455  VAL A N   1 
ATOM   2666 C  CA  . VAL A 1 455 ? 170.511 176.676 90.567  1.00 169.22 ? 455  VAL A CA  1 
ATOM   2667 C  C   . VAL A 1 455 ? 170.290 178.159 90.308  1.00 169.22 ? 455  VAL A C   1 
ATOM   2668 O  O   . VAL A 1 455 ? 169.179 178.672 90.491  1.00 169.22 ? 455  VAL A O   1 
ATOM   2669 C  CB  . VAL A 1 455 ? 169.670 175.815 89.611  1.00 169.22 ? 455  VAL A CB  1 
ATOM   2670 N  N   . VAL A 1 456 ? 171.347 178.849 89.886  1.00 169.58 ? 456  VAL A N   1 
ATOM   2671 C  CA  . VAL A 1 456 ? 171.288 180.268 89.575  1.00 169.58 ? 456  VAL A CA  1 
ATOM   2672 C  C   . VAL A 1 456 ? 171.904 180.486 88.197  1.00 169.58 ? 456  VAL A C   1 
ATOM   2673 O  O   . VAL A 1 456 ? 172.685 179.673 87.704  1.00 169.58 ? 456  VAL A O   1 
ATOM   2674 C  CB  . VAL A 1 456 ? 171.999 181.131 90.635  1.00 169.58 ? 456  VAL A CB  1 
ATOM   2675 N  N   . ALA A 1 457 ? 171.538 181.604 87.576  1.00 169.65 ? 457  ALA A N   1 
ATOM   2676 C  CA  . ALA A 1 457 ? 172.031 181.913 86.243  1.00 169.65 ? 457  ALA A CA  1 
ATOM   2677 C  C   . ALA A 1 457 ? 172.212 183.417 86.111  1.00 169.65 ? 457  ALA A C   1 
ATOM   2678 O  O   . ALA A 1 457 ? 171.350 184.191 86.533  1.00 169.65 ? 457  ALA A O   1 
ATOM   2679 C  CB  . ALA A 1 457 ? 171.076 181.393 85.162  1.00 169.65 ? 457  ALA A CB  1 
ATOM   2680 N  N   . GLU A 1 458 ? 173.340 183.817 85.527  1.00 169.33 ? 458  GLU A N   1 
ATOM   2681 C  CA  . GLU A 1 458 ? 173.605 185.217 85.229  1.00 169.33 ? 458  GLU A CA  1 
ATOM   2682 C  C   . GLU A 1 458 ? 173.117 185.628 83.846  1.00 169.33 ? 458  GLU A C   1 
ATOM   2683 O  O   . GLU A 1 458 ? 173.174 186.817 83.515  1.00 169.33 ? 458  GLU A O   1 
ATOM   2684 C  CB  . GLU A 1 458 ? 175.105 185.508 85.347  1.00 169.33 ? 458  GLU A CB  1 
ATOM   2685 N  N   . ASN A 1 459 ? 172.643 184.682 83.042  1.00 171.17 ? 459  ASN A N   1 
ATOM   2686 C  CA  . ASN A 1 459 ? 172.149 184.962 81.699  1.00 171.17 ? 459  ASN A CA  1 
ATOM   2687 C  C   . ASN A 1 459 ? 171.213 183.828 81.295  1.00 171.17 ? 459  ASN A C   1 
ATOM   2688 O  O   . ASN A 1 459 ? 170.931 182.922 82.087  1.00 171.17 ? 459  ASN A O   1 
ATOM   2689 C  CB  . ASN A 1 459 ? 173.310 185.133 80.713  1.00 171.17 ? 459  ASN A CB  1 
ATOM   2690 N  N   . THR A 1 460 ? 170.732 183.875 80.055  1.00 170.50 ? 460  THR A N   1 
ATOM   2691 C  CA  . THR A 1 460 ? 169.811 182.876 79.532  1.00 170.50 ? 460  THR A CA  1 
ATOM   2692 C  C   . THR A 1 460 ? 170.513 181.797 78.719  1.00 170.50 ? 460  THR A C   1 
ATOM   2693 O  O   . THR A 1 460 ? 169.842 180.953 78.117  1.00 170.50 ? 460  THR A O   1 
ATOM   2694 C  CB  . THR A 1 460 ? 168.732 183.547 78.679  1.00 170.50 ? 460  THR A CB  1 
ATOM   2695 N  N   . GLU A 1 461 ? 171.845 181.803 78.686  1.00 170.99 ? 461  GLU A N   1 
ATOM   2696 C  CA  . GLU A 1 461 ? 172.596 180.823 77.911  1.00 170.99 ? 461  GLU A CA  1 
ATOM   2697 C  C   . GLU A 1 461 ? 173.001 179.617 78.751  1.00 170.99 ? 461  GLU A C   1 
ATOM   2698 O  O   . GLU A 1 461 ? 172.830 178.472 78.321  1.00 170.99 ? 461  GLU A O   1 
ATOM   2699 C  CB  . GLU A 1 461 ? 173.836 181.481 77.297  1.00 170.99 ? 461  GLU A CB  1 
ATOM   2700 N  N   . HIS A 1 462 ? 173.536 179.854 79.947  1.00 171.46 ? 462  HIS A N   1 
ATOM   2701 C  CA  . HIS A 1 462 ? 173.988 178.780 80.818  1.00 171.46 ? 462  HIS A CA  1 
ATOM   2702 C  C   . HIS A 1 462 ? 173.509 179.041 82.238  1.00 171.46 ? 462  HIS A C   1 
ATOM   2703 O  O   . HIS A 1 462 ? 173.277 180.187 82.633  1.00 171.46 ? 462  HIS A O   1 
ATOM   2704 C  CB  . HIS A 1 462 ? 175.516 178.641 80.796  1.00 171.46 ? 462  HIS A CB  1 
ATOM   2705 N  N   . HIS A 1 463 ? 173.361 177.961 83.000  1.00 172.96 ? 463  HIS A N   1 
ATOM   2706 C  CA  . HIS A 1 463 ? 172.939 178.025 84.390  1.00 172.96 ? 463  HIS A CA  1 
ATOM   2707 C  C   . HIS A 1 463 ? 174.001 177.395 85.280  1.00 172.96 ? 463  HIS A C   1 
ATOM   2708 O  O   . HIS A 1 463 ? 174.655 176.419 84.899  1.00 172.96 ? 463  HIS A O   1 
ATOM   2709 C  CB  . HIS A 1 463 ? 171.595 177.316 84.597  1.00 172.96 ? 463  HIS A CB  1 
ATOM   2710 N  N   . GLN A 1 464 ? 174.169 177.963 86.470  1.00 171.15 ? 464  GLN A N   1 
ATOM   2711 C  CA  . GLN A 1 464 ? 175.157 177.502 87.435  1.00 171.15 ? 464  GLN A CA  1 
ATOM   2712 C  C   . GLN A 1 464 ? 174.450 176.882 88.632  1.00 171.15 ? 464  GLN A C   1 
ATOM   2713 O  O   . GLN A 1 464 ? 173.594 177.521 89.253  1.00 171.15 ? 464  GLN A O   1 
ATOM   2714 C  CB  . GLN A 1 464 ? 176.057 178.653 87.890  1.00 171.15 ? 464  GLN A CB  1 
ATOM   2715 N  N   . LEU A 1 465 ? 174.810 175.643 88.952  1.00 166.14 ? 465  LEU A N   1 
ATOM   2716 C  CA  . LEU A 1 465 ? 174.250 174.929 90.091  1.00 166.14 ? 465  LEU A CA  1 
ATOM   2717 C  C   . LEU A 1 465 ? 175.292 174.879 91.200  1.00 166.14 ? 465  LEU A C   1 
ATOM   2718 O  O   . LEU A 1 465 ? 176.425 174.440 90.973  1.00 166.14 ? 465  LEU A O   1 
ATOM   2719 C  CB  . LEU A 1 465 ? 173.818 173.518 89.692  1.00 166.14 ? 465  LEU A CB  1 
ATOM   2720 N  N   . VAL A 1 466 ? 174.911 175.328 92.392  1.00 160.94 ? 466  VAL A N   1 
ATOM   2721 C  CA  . VAL A 1 466 ? 175.801 175.360 93.547  1.00 160.94 ? 466  VAL A CA  1 
ATOM   2722 C  C   . VAL A 1 466 ? 175.194 174.486 94.634  1.00 160.94 ? 466  VAL A C   1 
ATOM   2723 O  O   . VAL A 1 466 ? 174.019 174.651 94.987  1.00 160.94 ? 466  VAL A O   1 
ATOM   2724 C  CB  . VAL A 1 466 ? 176.027 176.792 94.056  1.00 160.94 ? 466  VAL A CB  1 
ATOM   2725 C  CG1 . VAL A 1 466 ? 176.945 176.785 95.268  1.00 160.94 ? 466  VAL A CG1 1 
ATOM   2726 C  CG2 . VAL A 1 466 ? 176.601 177.663 92.950  1.00 160.94 ? 466  VAL A CG2 1 
ATOM   2727 N  N   . CYS A 1 467 ? 175.992 173.560 95.163  1.00 159.19 ? 467  CYS A N   1 
ATOM   2728 C  CA  . CYS A 1 467 ? 175.557 172.640 96.204  1.00 159.19 ? 467  CYS A CA  1 
ATOM   2729 C  C   . CYS A 1 467 ? 176.523 172.694 97.377  1.00 159.19 ? 467  CYS A C   1 
ATOM   2730 O  O   . CYS A 1 467 ? 177.739 172.789 97.187  1.00 159.19 ? 467  CYS A O   1 
ATOM   2731 C  CB  . CYS A 1 467 ? 175.467 171.204 95.673  1.00 159.19 ? 467  CYS A CB  1 
ATOM   2732 S  SG  . CYS A 1 467 ? 174.363 170.122 96.610  1.00 159.19 ? 467  CYS A SG  1 
ATOM   2733 N  N   . LYS A 1 468 ? 175.976 172.636 98.589  1.00 154.16 ? 468  LYS A N   1 
ATOM   2734 C  CA  . LYS A 1 468 ? 176.770 172.589 99.808  1.00 154.16 ? 468  LYS A CA  1 
ATOM   2735 C  C   . LYS A 1 468 ? 176.220 171.506 100.723 1.00 154.16 ? 468  LYS A C   1 
ATOM   2736 O  O   . LYS A 1 468 ? 175.032 171.175 100.665 1.00 154.16 ? 468  LYS A O   1 
ATOM   2737 C  CB  . LYS A 1 468 ? 176.776 173.940 100.536 1.00 154.16 ? 468  LYS A CB  1 
ATOM   2738 C  CG  . LYS A 1 468 ? 175.481 174.272 101.256 1.00 154.16 ? 468  LYS A CG  1 
ATOM   2739 C  CD  . LYS A 1 468 ? 175.730 175.168 102.460 1.00 154.16 ? 468  LYS A CD  1 
ATOM   2740 C  CE  . LYS A 1 468 ? 176.576 176.375 102.092 1.00 154.16 ? 468  LYS A CE  1 
ATOM   2741 N  NZ  . LYS A 1 468 ? 175.897 177.245 101.095 1.00 154.16 ? 468  LYS A NZ  1 
ATOM   2742 N  N   . GLY A 1 469 ? 177.089 170.950 101.557 1.00 151.77 ? 469  GLY A N   1 
ATOM   2743 C  CA  . GLY A 1 469 ? 176.672 169.902 102.466 1.00 151.77 ? 469  GLY A CA  1 
ATOM   2744 C  C   . GLY A 1 469 ? 177.867 169.298 103.168 1.00 151.77 ? 469  GLY A C   1 
ATOM   2745 O  O   . GLY A 1 469 ? 178.957 169.873 103.188 1.00 151.77 ? 469  GLY A O   1 
ATOM   2746 N  N   . ALA A 1 470 ? 177.643 168.123 103.752 1.00 155.12 ? 470  ALA A N   1 
ATOM   2747 C  CA  . ALA A 1 470 ? 178.720 167.401 104.409 1.00 155.12 ? 470  ALA A CA  1 
ATOM   2748 C  C   . ALA A 1 470 ? 179.792 167.014 103.394 1.00 155.12 ? 470  ALA A C   1 
ATOM   2749 O  O   . ALA A 1 470 ? 179.511 166.744 102.224 1.00 155.12 ? 470  ALA A O   1 
ATOM   2750 C  CB  . ALA A 1 470 ? 178.183 166.160 105.119 1.00 155.12 ? 470  ALA A CB  1 
ATOM   2751 N  N   . LEU A 1 471 ? 181.038 166.981 103.870 1.00 153.62 ? 471  LEU A N   1 
ATOM   2752 C  CA  . LEU A 1 471 ? 182.189 166.887 102.975 1.00 153.62 ? 471  LEU A CA  1 
ATOM   2753 C  C   . LEU A 1 471 ? 182.138 165.622 102.124 1.00 153.62 ? 471  LEU A C   1 
ATOM   2754 O  O   . LEU A 1 471 ? 182.252 165.683 100.892 1.00 153.62 ? 471  LEU A O   1 
ATOM   2755 C  CB  . LEU A 1 471 ? 183.476 166.922 103.798 1.00 153.62 ? 471  LEU A CB  1 
ATOM   2756 C  CG  . LEU A 1 471 ? 184.767 166.515 103.091 1.00 153.62 ? 471  LEU A CG  1 
ATOM   2757 C  CD1 . LEU A 1 471 ? 185.049 167.435 101.909 1.00 153.62 ? 471  LEU A CD1 1 
ATOM   2758 C  CD2 . LEU A 1 471 ? 185.925 166.489 104.062 1.00 153.62 ? 471  LEU A CD2 1 
ATOM   2759 N  N   . GLN A 1 472 ? 181.956 164.465 102.767 1.00 158.45 ? 472  GLN A N   1 
ATOM   2760 C  CA  . GLN A 1 472 ? 182.032 163.198 102.047 1.00 158.45 ? 472  GLN A CA  1 
ATOM   2761 C  C   . GLN A 1 472 ? 180.985 163.124 100.946 1.00 158.45 ? 472  GLN A C   1 
ATOM   2762 O  O   . GLN A 1 472 ? 181.281 162.682 99.829  1.00 158.45 ? 472  GLN A O   1 
ATOM   2763 C  CB  . GLN A 1 472 ? 181.874 162.030 103.019 1.00 158.45 ? 472  GLN A CB  1 
ATOM   2764 C  CG  . GLN A 1 472 ? 182.295 160.693 102.436 1.00 158.45 ? 472  GLN A CG  1 
ATOM   2765 C  CD  . GLN A 1 472 ? 183.725 160.706 101.934 1.00 158.45 ? 472  GLN A CD  1 
ATOM   2766 O  OE1 . GLN A 1 472 ? 183.976 160.574 100.737 1.00 158.45 ? 472  GLN A OE1 1 
ATOM   2767 N  NE2 . GLN A 1 472 ? 184.673 160.870 102.851 1.00 158.45 ? 472  GLN A NE2 1 
ATOM   2768 N  N   . GLU A 1 473 ? 179.760 163.562 101.238 1.00 159.24 ? 473  GLU A N   1 
ATOM   2769 C  CA  . GLU A 1 473 ? 178.729 163.608 100.208 1.00 159.24 ? 473  GLU A CA  1 
ATOM   2770 C  C   . GLU A 1 473 ? 179.108 164.573 99.092  1.00 159.24 ? 473  GLU A C   1 
ATOM   2771 O  O   . GLU A 1 473 ? 178.690 164.396 97.942  1.00 159.24 ? 473  GLU A O   1 
ATOM   2772 C  CB  . GLU A 1 473 ? 177.386 163.993 100.831 1.00 159.24 ? 473  GLU A CB  1 
ATOM   2773 C  CG  . GLU A 1 473 ? 176.785 162.925 101.743 1.00 159.24 ? 473  GLU A CG  1 
ATOM   2774 C  CD  . GLU A 1 473 ? 177.449 162.852 103.109 1.00 159.24 ? 473  GLU A CD  1 
ATOM   2775 O  OE1 . GLU A 1 473 ? 178.465 163.545 103.325 1.00 159.24 ? 473  GLU A OE1 1 
ATOM   2776 O  OE2 . GLU A 1 473 ? 176.951 162.096 103.970 1.00 159.24 ? 473  GLU A OE2 1 
ATOM   2777 N  N   . ILE A 1 474 ? 179.898 165.603 99.410  1.00 156.27 ? 474  ILE A N   1 
ATOM   2778 C  CA  . ILE A 1 474 ? 180.353 166.520 98.369  1.00 156.27 ? 474  ILE A CA  1 
ATOM   2779 C  C   . ILE A 1 474 ? 181.334 165.828 97.431  1.00 156.27 ? 474  ILE A C   1 
ATOM   2780 O  O   . ILE A 1 474 ? 181.210 165.932 96.205  1.00 156.27 ? 474  ILE A O   1 
ATOM   2781 C  CB  . ILE A 1 474 ? 180.957 167.795 98.984  1.00 156.27 ? 474  ILE A CB  1 
ATOM   2782 C  CG1 . ILE A 1 474 ? 179.886 168.582 99.738  1.00 156.27 ? 474  ILE A CG1 1 
ATOM   2783 C  CG2 . ILE A 1 474 ? 181.585 168.657 97.902  1.00 156.27 ? 474  ILE A CG2 1 
ATOM   2784 C  CD1 . ILE A 1 474 ? 178.750 169.051 98.861  1.00 156.27 ? 474  ILE A CD1 1 
ATOM   2785 N  N   . LEU A 1 475 ? 182.324 165.108 97.974  1.00 158.45 ? 475  LEU A N   1 
ATOM   2786 C  CA  . LEU A 1 475 ? 183.235 164.415 97.063  1.00 158.45 ? 475  LEU A CA  1 
ATOM   2787 C  C   . LEU A 1 475 ? 182.545 163.267 96.341  1.00 158.45 ? 475  LEU A C   1 
ATOM   2788 O  O   . LEU A 1 475 ? 182.980 162.873 95.253  1.00 158.45 ? 475  LEU A O   1 
ATOM   2789 C  CB  . LEU A 1 475 ? 184.492 163.886 97.763  1.00 158.45 ? 475  LEU A CB  1 
ATOM   2790 C  CG  . LEU A 1 475 ? 185.323 164.638 98.801  1.00 158.45 ? 475  LEU A CG  1 
ATOM   2791 C  CD1 . LEU A 1 475 ? 184.838 164.335 100.189 1.00 158.45 ? 475  LEU A CD1 1 
ATOM   2792 C  CD2 . LEU A 1 475 ? 186.799 164.291 98.660  1.00 158.45 ? 475  LEU A CD2 1 
ATOM   2793 N  N   . ASN A 1 476 ? 181.478 162.713 96.923  1.00 159.94 ? 476  ASN A N   1 
ATOM   2794 C  CA  . ASN A 1 476 ? 180.772 161.619 96.263  1.00 159.94 ? 476  ASN A CA  1 
ATOM   2795 C  C   . ASN A 1 476 ? 180.113 162.081 94.968  1.00 159.94 ? 476  ASN A C   1 
ATOM   2796 O  O   . ASN A 1 476 ? 179.922 161.283 94.043  1.00 159.94 ? 476  ASN A O   1 
ATOM   2797 C  CB  . ASN A 1 476 ? 179.735 161.013 97.207  1.00 159.94 ? 476  ASN A CB  1 
ATOM   2798 C  CG  . ASN A 1 476 ? 180.367 160.283 98.376  1.00 159.94 ? 476  ASN A CG  1 
ATOM   2799 O  OD1 . ASN A 1 476 ? 181.580 160.071 98.407  1.00 159.94 ? 476  ASN A OD1 1 
ATOM   2800 N  ND2 . ASN A 1 476 ? 179.548 159.897 99.346  1.00 159.94 ? 476  ASN A ND2 1 
ATOM   2801 N  N   . VAL A 1 477 ? 179.758 163.363 94.880  1.00 161.37 ? 477  VAL A N   1 
ATOM   2802 C  CA  . VAL A 1 477 ? 179.076 163.896 93.706  1.00 161.37 ? 477  VAL A CA  1 
ATOM   2803 C  C   . VAL A 1 477 ? 179.992 164.776 92.862  1.00 161.37 ? 477  VAL A C   1 
ATOM   2804 O  O   . VAL A 1 477 ? 179.536 165.382 91.888  1.00 161.37 ? 477  VAL A O   1 
ATOM   2805 C  CB  . VAL A 1 477 ? 177.806 164.664 94.104  1.00 161.37 ? 477  VAL A CB  1 
ATOM   2806 C  CG1 . VAL A 1 477 ? 176.766 163.710 94.675  1.00 161.37 ? 477  VAL A CG1 1 
ATOM   2807 C  CG2 . VAL A 1 477 ? 178.138 165.767 95.094  1.00 161.37 ? 477  VAL A CG2 1 
ATOM   2808 N  N   . CYS A 1 478 ? 181.273 164.862 93.209  1.00 160.94 ? 478  CYS A N   1 
ATOM   2809 C  CA  . CYS A 1 478 ? 182.220 165.705 92.493  1.00 160.94 ? 478  CYS A CA  1 
ATOM   2810 C  C   . CYS A 1 478 ? 183.261 164.843 91.792  1.00 160.94 ? 478  CYS A C   1 
ATOM   2811 O  O   . CYS A 1 478 ? 183.850 163.947 92.405  1.00 160.94 ? 478  CYS A O   1 
ATOM   2812 C  CB  . CYS A 1 478 ? 182.905 166.685 93.447  1.00 160.94 ? 478  CYS A CB  1 
ATOM   2813 S  SG  . CYS A 1 478 ? 181.907 168.127 93.874  1.00 160.94 ? 478  CYS A SG  1 
ATOM   2814 N  N   . SER A 1 479 ? 183.483 165.119 90.508  1.00 159.94 ? 479  SER A N   1 
ATOM   2815 C  CA  . SER A 1 479 ? 184.499 164.431 89.722  1.00 159.94 ? 479  SER A CA  1 
ATOM   2816 C  C   . SER A 1 479 ? 185.695 165.304 89.383  1.00 159.94 ? 479  SER A C   1 
ATOM   2817 O  O   . SER A 1 479 ? 186.759 164.772 89.063  1.00 159.94 ? 479  SER A O   1 
ATOM   2818 C  CB  . SER A 1 479 ? 183.894 163.896 88.419  1.00 159.94 ? 479  SER A CB  1 
ATOM   2819 O  OG  . SER A 1 479 ? 183.366 164.951 87.634  1.00 159.94 ? 479  SER A OG  1 
ATOM   2820 N  N   . GLN A 1 480 ? 185.541 166.624 89.434  1.00 161.30 ? 480  GLN A N   1 
ATOM   2821 C  CA  . GLN A 1 480 ? 186.618 167.562 89.163  1.00 161.30 ? 480  GLN A CA  1 
ATOM   2822 C  C   . GLN A 1 480 ? 186.638 168.636 90.241  1.00 161.30 ? 480  GLN A C   1 
ATOM   2823 O  O   . GLN A 1 480 ? 185.620 168.913 90.881  1.00 161.30 ? 480  GLN A O   1 
ATOM   2824 C  CB  . GLN A 1 480 ? 186.457 168.207 87.779  1.00 161.30 ? 480  GLN A CB  1 
ATOM   2825 C  CG  . GLN A 1 480 ? 185.346 169.246 87.695  1.00 161.30 ? 480  GLN A CG  1 
ATOM   2826 C  CD  . GLN A 1 480 ? 183.968 168.632 87.515  1.00 161.30 ? 480  GLN A CD  1 
ATOM   2827 O  OE1 . GLN A 1 480 ? 183.711 167.507 87.946  1.00 161.30 ? 480  GLN A OE1 1 
ATOM   2828 N  NE2 . GLN A 1 480 ? 183.072 169.373 86.875  1.00 161.30 ? 480  GLN A NE2 1 
ATOM   2829 N  N   . VAL A 1 481 ? 187.812 169.222 90.458  1.00 158.79 ? 481  VAL A N   1 
ATOM   2830 C  CA  . VAL A 1 481 ? 187.985 170.308 91.417  1.00 158.79 ? 481  VAL A CA  1 
ATOM   2831 C  C   . VAL A 1 481 ? 188.841 171.394 90.783  1.00 158.79 ? 481  VAL A C   1 
ATOM   2832 O  O   . VAL A 1 481 ? 189.563 171.146 89.812  1.00 158.79 ? 481  VAL A O   1 
ATOM   2833 C  CB  . VAL A 1 481 ? 188.618 169.823 92.738  1.00 158.79 ? 481  VAL A CB  1 
ATOM   2834 C  CG1 . VAL A 1 481 ? 187.799 168.699 93.347  1.00 158.79 ? 481  VAL A CG1 1 
ATOM   2835 C  CG2 . VAL A 1 481 ? 190.049 169.369 92.500  1.00 158.79 ? 481  VAL A CG2 1 
ATOM   2836 N  N   . ARG A 1 482 ? 188.756 172.602 91.335  1.00 157.04 ? 482  ARG A N   1 
ATOM   2837 C  CA  . ARG A 1 482 ? 189.567 173.728 90.887  1.00 157.04 ? 482  ARG A CA  1 
ATOM   2838 C  C   . ARG A 1 482 ? 190.746 173.885 91.841  1.00 157.04 ? 482  ARG A C   1 
ATOM   2839 O  O   . ARG A 1 482 ? 190.581 174.360 92.969  1.00 157.04 ? 482  ARG A O   1 
ATOM   2840 C  CB  . ARG A 1 482 ? 188.734 175.006 90.830  1.00 157.04 ? 482  ARG A CB  1 
ATOM   2841 C  CG  . ARG A 1 482 ? 187.313 174.803 90.336  1.00 157.04 ? 482  ARG A CG  1 
ATOM   2842 C  CD  . ARG A 1 482 ? 187.224 175.008 88.836  1.00 157.04 ? 482  ARG A CD  1 
ATOM   2843 N  NE  . ARG A 1 482 ? 187.883 176.240 88.418  1.00 157.04 ? 482  ARG A NE  1 
ATOM   2844 C  CZ  . ARG A 1 482 ? 187.255 177.385 88.186  1.00 157.04 ? 482  ARG A CZ  1 
ATOM   2845 N  NH1 . ARG A 1 482 ? 185.943 177.492 88.316  1.00 157.04 ? 482  ARG A NH1 1 
ATOM   2846 N  NH2 . ARG A 1 482 ? 187.961 178.448 87.812  1.00 157.04 ? 482  ARG A NH2 1 
ATOM   2847 N  N   . HIS A 1 483 ? 191.933 173.495 91.388  1.00 158.62 ? 483  HIS A N   1 
ATOM   2848 C  CA  . HIS A 1 483 ? 193.143 173.564 92.197  1.00 158.62 ? 483  HIS A CA  1 
ATOM   2849 C  C   . HIS A 1 483 ? 193.934 174.799 91.787  1.00 158.62 ? 483  HIS A C   1 
ATOM   2850 O  O   . HIS A 1 483 ? 194.405 174.888 90.647  1.00 158.62 ? 483  HIS A O   1 
ATOM   2851 C  CB  . HIS A 1 483 ? 193.980 172.297 92.028  1.00 158.62 ? 483  HIS A CB  1 
ATOM   2852 C  CG  . HIS A 1 483 ? 195.123 172.190 92.989  1.00 158.62 ? 483  HIS A CG  1 
ATOM   2853 N  ND1 . HIS A 1 483 ? 196.195 173.055 92.974  1.00 158.62 ? 483  HIS A ND1 1 
ATOM   2854 C  CD2 . HIS A 1 483 ? 195.359 171.315 93.996  1.00 158.62 ? 483  HIS A CD2 1 
ATOM   2855 C  CE1 . HIS A 1 483 ? 197.043 172.719 93.930  1.00 158.62 ? 483  HIS A CE1 1 
ATOM   2856 N  NE2 . HIS A 1 483 ? 196.559 171.666 94.565  1.00 158.62 ? 483  HIS A NE2 1 
ATOM   2857 N  N   . ASN A 1 484 ? 194.078 175.746 92.718  1.00 159.98 ? 484  ASN A N   1 
ATOM   2858 C  CA  . ASN A 1 484 ? 194.742 177.025 92.457  1.00 159.98 ? 484  ASN A CA  1 
ATOM   2859 C  C   . ASN A 1 484 ? 194.112 177.744 91.267  1.00 159.98 ? 484  ASN A C   1 
ATOM   2860 O  O   . ASN A 1 484 ? 194.803 178.351 90.446  1.00 159.98 ? 484  ASN A O   1 
ATOM   2861 C  CB  . ASN A 1 484 ? 196.247 176.840 92.246  1.00 159.98 ? 484  ASN A CB  1 
ATOM   2862 C  CG  . ASN A 1 484 ? 196.976 176.484 93.525  1.00 159.98 ? 484  ASN A CG  1 
ATOM   2863 O  OD1 . ASN A 1 484 ? 196.647 176.985 94.600  1.00 159.98 ? 484  ASN A OD1 1 
ATOM   2864 N  ND2 . ASN A 1 484 ? 197.980 175.623 93.413  1.00 159.98 ? 484  ASN A ND2 1 
ATOM   2865 N  N   . GLY A 1 485 ? 192.787 177.673 91.171  1.00 161.80 ? 485  GLY A N   1 
ATOM   2866 C  CA  . GLY A 1 485 ? 192.079 178.284 90.066  1.00 161.80 ? 485  GLY A CA  1 
ATOM   2867 C  C   . GLY A 1 485 ? 192.179 177.542 88.755  1.00 161.80 ? 485  GLY A C   1 
ATOM   2868 O  O   . GLY A 1 485 ? 191.781 178.089 87.720  1.00 161.80 ? 485  GLY A O   1 
ATOM   2869 N  N   . GLU A 1 486 ? 192.697 176.316 88.761  1.00 161.50 ? 486  GLU A N   1 
ATOM   2870 C  CA  . GLU A 1 486 ? 192.870 175.520 87.555  1.00 161.50 ? 486  GLU A CA  1 
ATOM   2871 C  C   . GLU A 1 486 ? 192.046 174.247 87.673  1.00 161.50 ? 486  GLU A C   1 
ATOM   2872 O  O   . GLU A 1 486 ? 192.077 173.578 88.711  1.00 161.50 ? 486  GLU A O   1 
ATOM   2873 C  CB  . GLU A 1 486 ? 194.349 175.187 87.327  1.00 161.50 ? 486  GLU A CB  1 
ATOM   2874 C  CG  . GLU A 1 486 ? 194.602 173.975 86.442  1.00 161.50 ? 486  GLU A CG  1 
ATOM   2875 C  CD  . GLU A 1 486 ? 194.807 172.699 87.237  1.00 161.50 ? 486  GLU A CD  1 
ATOM   2876 O  OE1 . GLU A 1 486 ? 194.986 171.631 86.614  1.00 161.50 ? 486  GLU A OE1 1 
ATOM   2877 O  OE2 . GLU A 1 486 ? 194.790 172.764 88.484  1.00 161.50 ? 486  GLU A OE2 1 
ATOM   2878 N  N   . ILE A 1 487 ? 191.310 173.918 86.612  1.00 162.43 ? 487  ILE A N   1 
ATOM   2879 C  CA  . ILE A 1 487 ? 190.513 172.699 86.604  1.00 162.43 ? 487  ILE A CA  1 
ATOM   2880 C  C   . ILE A 1 487 ? 191.438 171.497 86.482  1.00 162.43 ? 487  ILE A C   1 
ATOM   2881 O  O   . ILE A 1 487 ? 192.271 171.423 85.569  1.00 162.43 ? 487  ILE A O   1 
ATOM   2882 C  CB  . ILE A 1 487 ? 189.487 172.731 85.462  1.00 162.43 ? 487  ILE A CB  1 
ATOM   2883 C  CG1 . ILE A 1 487 ? 188.533 173.915 85.635  1.00 162.43 ? 487  ILE A CG1 1 
ATOM   2884 C  CG2 . ILE A 1 487 ? 188.711 171.425 85.407  1.00 162.43 ? 487  ILE A CG2 1 
ATOM   2885 C  CD1 . ILE A 1 487 ? 187.635 174.153 84.442  1.00 162.43 ? 487  ILE A CD1 1 
ATOM   2886 N  N   . VAL A 1 488 ? 191.296 170.550 87.403  1.00 162.05 ? 488  VAL A N   1 
ATOM   2887 C  CA  . VAL A 1 488 ? 192.137 169.357 87.423  1.00 162.05 ? 488  VAL A CA  1 
ATOM   2888 C  C   . VAL A 1 488 ? 191.257 168.143 87.701  1.00 162.05 ? 488  VAL A C   1 
ATOM   2889 O  O   . VAL A 1 488 ? 190.302 168.241 88.487  1.00 162.05 ? 488  VAL A O   1 
ATOM   2890 C  CB  . VAL A 1 488 ? 193.265 169.498 88.461  1.00 162.05 ? 488  VAL A CB  1 
ATOM   2891 C  CG1 . VAL A 1 488 ? 192.694 169.662 89.861  1.00 162.05 ? 488  VAL A CG1 1 
ATOM   2892 C  CG2 . VAL A 1 488 ? 194.217 168.311 88.402  1.00 162.05 ? 488  VAL A CG2 1 
ATOM   2893 N  N   . PRO A 1 489 ? 191.505 167.001 87.060  1.00 160.02 ? 489  PRO A N   1 
ATOM   2894 C  CA  . PRO A 1 489 ? 190.779 165.783 87.432  1.00 160.02 ? 489  PRO A CA  1 
ATOM   2895 C  C   . PRO A 1 489 ? 191.037 165.416 88.885  1.00 160.02 ? 489  PRO A C   1 
ATOM   2896 O  O   . PRO A 1 489 ? 192.147 165.563 89.401  1.00 160.02 ? 489  PRO A O   1 
ATOM   2897 C  CB  . PRO A 1 489 ? 191.341 164.725 86.476  1.00 160.02 ? 489  PRO A CB  1 
ATOM   2898 C  CG  . PRO A 1 489 ? 191.831 165.503 85.305  1.00 160.02 ? 489  PRO A CG  1 
ATOM   2899 C  CD  . PRO A 1 489 ? 192.324 166.811 85.851  1.00 160.02 ? 489  PRO A CD  1 
ATOM   2900 N  N   . LEU A 1 490 ? 189.988 164.933 89.545  1.00 157.16 ? 490  LEU A N   1 
ATOM   2901 C  CA  . LEU A 1 490 ? 190.029 164.651 90.979  1.00 157.16 ? 490  LEU A CA  1 
ATOM   2902 C  C   . LEU A 1 490 ? 190.461 163.204 91.183  1.00 157.16 ? 490  LEU A C   1 
ATOM   2903 O  O   . LEU A 1 490 ? 189.641 162.287 91.254  1.00 157.16 ? 490  LEU A O   1 
ATOM   2904 C  CB  . LEU A 1 490 ? 188.671 164.932 91.611  1.00 157.16 ? 490  LEU A CB  1 
ATOM   2905 C  CG  . LEU A 1 490 ? 188.552 164.756 93.122  1.00 157.16 ? 490  LEU A CG  1 
ATOM   2906 C  CD1 . LEU A 1 490 ? 189.578 165.610 93.844  1.00 157.16 ? 490  LEU A CD1 1 
ATOM   2907 C  CD2 . LEU A 1 490 ? 187.143 165.083 93.597  1.00 157.16 ? 490  LEU A CD2 1 
ATOM   2908 N  N   . ASP A 1 491 ? 191.773 162.997 91.278  1.00 152.50 ? 491  ASP A N   1 
ATOM   2909 C  CA  . ASP A 1 491 ? 192.320 161.665 91.475  1.00 152.50 ? 491  ASP A CA  1 
ATOM   2910 C  C   . ASP A 1 491 ? 192.514 161.372 92.962  1.00 152.50 ? 491  ASP A C   1 
ATOM   2911 O  O   . ASP A 1 491 ? 192.240 162.203 93.832  1.00 152.50 ? 491  ASP A O   1 
ATOM   2912 C  CB  . ASP A 1 491 ? 193.638 161.506 90.717  1.00 152.50 ? 491  ASP A CB  1 
ATOM   2913 C  CG  . ASP A 1 491 ? 194.542 162.712 90.860  1.00 152.50 ? 491  ASP A CG  1 
ATOM   2914 O  OD1 . ASP A 1 491 ? 194.073 163.748 91.372  1.00 152.50 ? 491  ASP A OD1 1 
ATOM   2915 O  OD2 . ASP A 1 491 ? 195.722 162.624 90.461  1.00 152.50 ? 491  ASP A OD2 1 
ATOM   2916 N  N   . ASP A 1 492 ? 193.013 160.164 93.243  1.00 146.97 ? 492  ASP A N   1 
ATOM   2917 C  CA  . ASP A 1 492 ? 193.074 159.667 94.615  1.00 146.97 ? 492  ASP A CA  1 
ATOM   2918 C  C   . ASP A 1 492 ? 193.989 160.507 95.497  1.00 146.97 ? 492  ASP A C   1 
ATOM   2919 O  O   . ASP A 1 492 ? 193.695 160.700 96.684  1.00 146.97 ? 492  ASP A O   1 
ATOM   2920 C  CB  . ASP A 1 492 ? 193.528 158.208 94.621  1.00 146.97 ? 492  ASP A CB  1 
ATOM   2921 C  CG  . ASP A 1 492 ? 192.754 157.362 95.612  1.00 146.97 ? 492  ASP A CG  1 
ATOM   2922 O  OD1 . ASP A 1 492 ? 192.314 157.910 96.645  1.00 146.97 ? 492  ASP A OD1 1 
ATOM   2923 O  OD2 . ASP A 1 492 ? 192.584 156.152 95.358  1.00 146.97 ? 492  ASP A OD2 1 
ATOM   2924 N  N   . ILE A 1 493 ? 195.102 161.000 94.948  1.00 144.56 ? 493  ILE A N   1 
ATOM   2925 C  CA  . ILE A 1 493 ? 196.034 161.797 95.743  1.00 144.56 ? 493  ILE A CA  1 
ATOM   2926 C  C   . ILE A 1 493 ? 195.352 163.063 96.243  1.00 144.56 ? 493  ILE A C   1 
ATOM   2927 O  O   . ILE A 1 493 ? 195.544 163.484 97.391  1.00 144.56 ? 493  ILE A O   1 
ATOM   2928 C  CB  . ILE A 1 493 ? 197.298 162.119 94.927  1.00 144.56 ? 493  ILE A CB  1 
ATOM   2929 C  CG1 . ILE A 1 493 ? 197.810 160.863 94.218  1.00 144.56 ? 493  ILE A CG1 1 
ATOM   2930 C  CG2 . ILE A 1 493 ? 198.377 162.703 95.827  1.00 144.56 ? 493  ILE A CG2 1 
ATOM   2931 C  CD1 . ILE A 1 493 ? 198.225 159.754 95.160  1.00 144.56 ? 493  ILE A CD1 1 
ATOM   2932 N  N   . MET A 1 494 ? 194.548 163.694 95.384  1.00 143.97 ? 494  MET A N   1 
ATOM   2933 C  CA  . MET A 1 494 ? 193.788 164.860 95.818  1.00 143.97 ? 494  MET A CA  1 
ATOM   2934 C  C   . MET A 1 494 ? 192.765 164.503 96.888  1.00 143.97 ? 494  MET A C   1 
ATOM   2935 O  O   . MET A 1 494 ? 192.569 165.282 97.826  1.00 143.97 ? 494  MET A O   1 
ATOM   2936 C  CB  . MET A 1 494 ? 193.107 165.531 94.626  1.00 143.97 ? 494  MET A CB  1 
ATOM   2937 C  CG  . MET A 1 494 ? 194.006 166.040 93.479  1.00 143.97 ? 494  MET A CG  1 
ATOM   2938 S  SD  . MET A 1 494 ? 195.527 166.970 93.839  1.00 143.97 ? 494  MET A SD  1 
ATOM   2939 C  CE  . MET A 1 494 ? 196.724 165.724 94.319  1.00 143.97 ? 494  MET A CE  1 
ATOM   2940 N  N   . LEU A 1 495 ? 192.105 163.346 96.775  1.00 140.97 ? 495  LEU A N   1 
ATOM   2941 C  CA  . LEU A 1 495 ? 191.195 162.924 97.837  1.00 140.97 ? 495  LEU A CA  1 
ATOM   2942 C  C   . LEU A 1 495 ? 191.931 162.790 99.161  1.00 140.97 ? 495  LEU A C   1 
ATOM   2943 O  O   . LEU A 1 495 ? 191.442 163.241 100.202 1.00 140.97 ? 495  LEU A O   1 
ATOM   2944 C  CB  . LEU A 1 495 ? 190.510 161.601 97.486  1.00 140.97 ? 495  LEU A CB  1 
ATOM   2945 C  CG  . LEU A 1 495 ? 190.220 161.200 96.044  1.00 140.97 ? 495  LEU A CG  1 
ATOM   2946 C  CD1 . LEU A 1 495 ? 189.558 159.834 96.008  1.00 140.97 ? 495  LEU A CD1 1 
ATOM   2947 C  CD2 . LEU A 1 495 ? 189.319 162.223 95.402  1.00 140.97 ? 495  LEU A CD2 1 
ATOM   2948 N  N   . ARG A 1 496 ? 193.113 162.172 99.142  1.00 138.94 ? 496  ARG A N   1 
ATOM   2949 C  CA  . ARG A 1 496 ? 193.860 161.989 100.382 1.00 138.94 ? 496  ARG A CA  1 
ATOM   2950 C  C   . ARG A 1 496 ? 194.316 163.325 100.958 1.00 138.94 ? 496  ARG A C   1 
ATOM   2951 O  O   . ARG A 1 496 ? 194.245 163.542 102.173 1.00 138.94 ? 496  ARG A O   1 
ATOM   2952 C  CB  . ARG A 1 496 ? 195.053 161.064 100.146 1.00 138.94 ? 496  ARG A CB  1 
ATOM   2953 C  CG  . ARG A 1 496 ? 194.732 159.593 100.359 1.00 138.94 ? 496  ARG A CG  1 
ATOM   2954 C  CD  . ARG A 1 496 ? 195.979 158.776 100.658 1.00 138.94 ? 496  ARG A CD  1 
ATOM   2955 N  NE  . ARG A 1 496 ? 196.935 158.799 99.558  1.00 138.94 ? 496  ARG A NE  1 
ATOM   2956 C  CZ  . ARG A 1 496 ? 198.039 159.534 99.541  1.00 138.94 ? 496  ARG A CZ  1 
ATOM   2957 N  NH1 . ARG A 1 496 ? 198.360 160.322 100.554 1.00 138.94 ? 496  ARG A NH1 1 
ATOM   2958 N  NH2 . ARG A 1 496 ? 198.842 159.475 98.483  1.00 138.94 ? 496  ARG A NH2 1 
ATOM   2959 N  N   . LYS A 1 497 ? 194.784 164.236 100.102 1.00 132.30 ? 497  LYS A N   1 
ATOM   2960 C  CA  . LYS A 1 497 ? 195.228 165.541 100.587 1.00 132.30 ? 497  LYS A CA  1 
ATOM   2961 C  C   . LYS A 1 497 ? 194.065 166.345 101.160 1.00 132.30 ? 497  LYS A C   1 
ATOM   2962 O  O   . LYS A 1 497 ? 194.210 167.008 102.195 1.00 132.30 ? 497  LYS A O   1 
ATOM   2963 C  CB  . LYS A 1 497 ? 195.920 166.311 99.464  1.00 132.30 ? 497  LYS A CB  1 
ATOM   2964 C  CG  . LYS A 1 497 ? 196.366 167.709 99.854  1.00 132.30 ? 497  LYS A CG  1 
ATOM   2965 C  CD  . LYS A 1 497 ? 196.568 168.586 98.632  1.00 132.30 ? 497  LYS A CD  1 
ATOM   2966 C  CE  . LYS A 1 497 ? 196.972 169.995 99.030  1.00 132.30 ? 497  LYS A CE  1 
ATOM   2967 N  NZ  . LYS A 1 497 ? 197.431 170.791 97.859  1.00 132.30 ? 497  LYS A NZ  1 
ATOM   2968 N  N   . ILE A 1 498 ? 192.906 166.302 100.499 1.00 130.60 ? 498  ILE A N   1 
ATOM   2969 C  CA  . ILE A 1 498 ? 191.723 166.976 101.024 1.00 130.60 ? 498  ILE A CA  1 
ATOM   2970 C  C   . ILE A 1 498 ? 191.310 166.360 102.353 1.00 130.60 ? 498  ILE A C   1 
ATOM   2971 O  O   . ILE A 1 498 ? 190.955 167.071 103.300 1.00 130.60 ? 498  ILE A O   1 
ATOM   2972 C  CB  . ILE A 1 498 ? 190.579 166.930 99.995  1.00 130.60 ? 498  ILE A CB  1 
ATOM   2973 C  CG1 . ILE A 1 498 ? 190.919 167.793 98.779  1.00 130.60 ? 498  ILE A CG1 1 
ATOM   2974 C  CG2 . ILE A 1 498 ? 189.273 167.390 100.621 1.00 130.60 ? 498  ILE A CG2 1 
ATOM   2975 C  CD1 . ILE A 1 498 ? 190.066 167.497 97.566  1.00 130.60 ? 498  ILE A CD1 1 
ATOM   2976 N  N   . LYS A 1 499 ? 191.343 165.030 102.444 1.00 123.68 ? 499  LYS A N   1 
ATOM   2977 C  CA  . LYS A 1 499 ? 191.021 164.379 103.706 1.00 123.68 ? 499  LYS A CA  1 
ATOM   2978 C  C   . LYS A 1 499 ? 191.965 164.848 104.803 1.00 123.68 ? 499  LYS A C   1 
ATOM   2979 O  O   . LYS A 1 499 ? 191.532 165.117 105.926 1.00 123.68 ? 499  LYS A O   1 
ATOM   2980 C  CB  . LYS A 1 499 ? 191.077 162.859 103.543 1.00 123.68 ? 499  LYS A CB  1 
ATOM   2981 C  CG  . LYS A 1 499 ? 191.738 162.111 104.695 1.00 123.68 ? 499  LYS A CG  1 
ATOM   2982 C  CD  . LYS A 1 499 ? 190.780 161.922 105.865 1.00 123.68 ? 499  LYS A CD  1 
ATOM   2983 C  CE  . LYS A 1 499 ? 191.327 160.926 106.872 1.00 123.68 ? 499  LYS A CE  1 
ATOM   2984 N  NZ  . LYS A 1 499 ? 190.595 160.986 108.167 1.00 123.68 ? 499  LYS A NZ  1 
ATOM   2985 N  N   . ARG A 1 500 ? 193.253 164.985 104.485 1.00 122.24 ? 500  ARG A N   1 
ATOM   2986 C  CA  . ARG A 1 500 ? 194.215 165.451 105.480 1.00 122.24 ? 500  ARG A CA  1 
ATOM   2987 C  C   . ARG A 1 500 ? 193.928 166.886 105.910 1.00 122.24 ? 500  ARG A C   1 
ATOM   2988 O  O   . ARG A 1 500 ? 193.988 167.208 107.104 1.00 122.24 ? 500  ARG A O   1 
ATOM   2989 C  CB  . ARG A 1 500 ? 195.637 165.320 104.930 1.00 122.24 ? 500  ARG A CB  1 
ATOM   2990 C  CG  . ARG A 1 500 ? 196.615 166.376 105.425 1.00 122.24 ? 500  ARG A CG  1 
ATOM   2991 C  CD  . ARG A 1 500 ? 196.910 167.414 104.351 1.00 122.24 ? 500  ARG A CD  1 
ATOM   2992 N  NE  . ARG A 1 500 ? 197.572 166.832 103.189 1.00 122.24 ? 500  ARG A NE  1 
ATOM   2993 C  CZ  . ARG A 1 500 ? 198.836 166.431 103.165 1.00 122.24 ? 500  ARG A CZ  1 
ATOM   2994 N  NH1 . ARG A 1 500 ? 199.619 166.545 104.226 1.00 122.24 ? 500  ARG A NH1 1 
ATOM   2995 N  NH2 . ARG A 1 500 ? 199.329 165.906 102.047 1.00 122.24 ? 500  ARG A NH2 1 
ATOM   2996 N  N   . VAL A 1 501 ? 193.609 167.766 104.958 1.00 118.11 ? 501  VAL A N   1 
ATOM   2997 C  CA  . VAL A 1 501 ? 193.423 169.171 105.316 1.00 118.11 ? 501  VAL A CA  1 
ATOM   2998 C  C   . VAL A 1 501 ? 192.145 169.356 106.132 1.00 118.11 ? 501  VAL A C   1 
ATOM   2999 O  O   . VAL A 1 501 ? 192.127 170.107 107.116 1.00 118.11 ? 501  VAL A O   1 
ATOM   3000 C  CB  . VAL A 1 501 ? 193.460 170.074 104.066 1.00 118.11 ? 501  VAL A CB  1 
ATOM   3001 C  CG1 . VAL A 1 501 ? 192.237 169.887 103.191 1.00 118.11 ? 501  VAL A CG1 1 
ATOM   3002 C  CG2 . VAL A 1 501 ? 193.604 171.532 104.475 1.00 118.11 ? 501  VAL A CG2 1 
ATOM   3003 N  N   . THR A 1 502 ? 191.066 168.659 105.769 1.00 114.61 ? 502  THR A N   1 
ATOM   3004 C  CA  . THR A 1 502 ? 189.863 168.751 106.591 1.00 114.61 ? 502  THR A CA  1 
ATOM   3005 C  C   . THR A 1 502 ? 190.014 167.993 107.902 1.00 114.61 ? 502  THR A C   1 
ATOM   3006 O  O   . THR A 1 502 ? 189.343 168.326 108.882 1.00 114.61 ? 502  THR A O   1 
ATOM   3007 C  CB  . THR A 1 502 ? 188.633 168.264 105.828 1.00 114.61 ? 502  THR A CB  1 
ATOM   3008 O  OG1 . THR A 1 502 ? 188.502 166.844 105.968 1.00 114.61 ? 502  THR A OG1 1 
ATOM   3009 C  CG2 . THR A 1 502 ? 188.691 168.677 104.366 1.00 114.61 ? 502  THR A CG2 1 
ATOM   3010 N  N   . ASP A 1 503 ? 190.895 166.993 107.955 1.00 111.83 ? 503  ASP A N   1 
ATOM   3011 C  CA  . ASP A 1 503 ? 191.235 166.381 109.232 1.00 111.83 ? 503  ASP A CA  1 
ATOM   3012 C  C   . ASP A 1 503 ? 191.906 167.393 110.148 1.00 111.83 ? 503  ASP A C   1 
ATOM   3013 O  O   . ASP A 1 503 ? 191.592 167.471 111.340 1.00 111.83 ? 503  ASP A O   1 
ATOM   3014 C  CB  . ASP A 1 503 ? 192.139 165.170 108.995 1.00 111.83 ? 503  ASP A CB  1 
ATOM   3015 C  CG  . ASP A 1 503 ? 192.222 164.249 110.198 1.00 111.83 ? 503  ASP A CG  1 
ATOM   3016 O  OD1 . ASP A 1 503 ? 191.889 164.683 111.318 1.00 111.83 ? 503  ASP A OD1 1 
ATOM   3017 O  OD2 . ASP A 1 503 ? 192.626 163.081 110.019 1.00 111.83 ? 503  ASP A OD2 1 
ATOM   3018 N  N   . THR A 1 504 ? 192.829 168.186 109.600 1.00 110.44 ? 504  THR A N   1 
ATOM   3019 C  CA  . THR A 1 504 ? 193.441 169.257 110.381 1.00 110.44 ? 504  THR A CA  1 
ATOM   3020 C  C   . THR A 1 504 ? 192.394 170.267 110.834 1.00 110.44 ? 504  THR A C   1 
ATOM   3021 O  O   . THR A 1 504 ? 192.399 170.707 111.992 1.00 110.44 ? 504  THR A O   1 
ATOM   3022 C  CB  . THR A 1 504 ? 194.529 169.951 109.563 1.00 110.44 ? 504  THR A CB  1 
ATOM   3023 O  OG1 . THR A 1 504 ? 195.451 168.975 109.064 1.00 110.44 ? 504  THR A OG1 1 
ATOM   3024 C  CG2 . THR A 1 504 ? 195.276 170.959 110.422 1.00 110.44 ? 504  THR A CG2 1 
ATOM   3025 N  N   . LEU A 1 505 ? 191.482 170.639 109.933 1.00 106.92 ? 505  LEU A N   1 
ATOM   3026 C  CA  . LEU A 1 505 ? 190.434 171.589 110.293 1.00 106.92 ? 505  LEU A CA  1 
ATOM   3027 C  C   . LEU A 1 505 ? 189.557 171.049 111.417 1.00 106.92 ? 505  LEU A C   1 
ATOM   3028 O  O   . LEU A 1 505 ? 189.241 171.771 112.369 1.00 106.92 ? 505  LEU A O   1 
ATOM   3029 C  CB  . LEU A 1 505 ? 189.586 171.924 109.067 1.00 106.92 ? 505  LEU A CB  1 
ATOM   3030 C  CG  . LEU A 1 505 ? 190.259 172.746 107.967 1.00 106.92 ? 505  LEU A CG  1 
ATOM   3031 C  CD1 . LEU A 1 505 ? 189.213 173.459 107.128 1.00 106.92 ? 505  LEU A CD1 1 
ATOM   3032 C  CD2 . LEU A 1 505 ? 191.242 173.744 108.560 1.00 106.92 ? 505  LEU A CD2 1 
ATOM   3033 N  N   . ASN A 1 506 ? 189.157 169.781 111.325 1.00 102.31 ? 506  ASN A N   1 
ATOM   3034 C  CA  . ASN A 1 506 ? 188.328 169.184 112.366 1.00 102.31 ? 506  ASN A CA  1 
ATOM   3035 C  C   . ASN A 1 506 ? 189.083 169.087 113.684 1.00 102.31 ? 506  ASN A C   1 
ATOM   3036 O  O   . ASN A 1 506 ? 188.511 169.337 114.751 1.00 102.31 ? 506  ASN A O   1 
ATOM   3037 C  CB  . ASN A 1 506 ? 187.840 167.808 111.920 1.00 102.31 ? 506  ASN A CB  1 
ATOM   3038 C  CG  . ASN A 1 506 ? 186.669 167.890 110.965 1.00 102.31 ? 506  ASN A CG  1 
ATOM   3039 O  OD1 . ASN A 1 506 ? 186.336 168.965 110.469 1.00 102.31 ? 506  ASN A OD1 1 
ATOM   3040 N  ND2 . ASN A 1 506 ? 186.038 166.753 110.700 1.00 102.31 ? 506  ASN A ND2 1 
ATOM   3041 N  N   . ARG A 1 507 ? 190.367 168.722 113.634 1.00 101.83 ? 507  ARG A N   1 
ATOM   3042 C  CA  . ARG A 1 507 ? 191.165 168.674 114.852 1.00 101.83 ? 507  ARG A CA  1 
ATOM   3043 C  C   . ARG A 1 507 ? 191.281 170.050 115.487 1.00 101.83 ? 507  ARG A C   1 
ATOM   3044 O  O   . ARG A 1 507 ? 191.394 170.163 116.712 1.00 101.83 ? 507  ARG A O   1 
ATOM   3045 C  CB  . ARG A 1 507 ? 192.551 168.107 114.555 1.00 101.83 ? 507  ARG A CB  1 
ATOM   3046 C  CG  . ARG A 1 507 ? 193.011 167.055 115.547 1.00 101.83 ? 507  ARG A CG  1 
ATOM   3047 C  CD  . ARG A 1 507 ? 194.438 166.616 115.264 1.00 101.83 ? 507  ARG A CD  1 
ATOM   3048 N  NE  . ARG A 1 507 ? 194.723 166.539 113.836 1.00 101.83 ? 507  ARG A NE  1 
ATOM   3049 C  CZ  . ARG A 1 507 ? 194.273 165.589 113.028 1.00 101.83 ? 507  ARG A CZ  1 
ATOM   3050 N  NH1 . ARG A 1 507 ? 193.508 164.606 113.474 1.00 101.83 ? 507  ARG A NH1 1 
ATOM   3051 N  NH2 . ARG A 1 507 ? 194.601 165.625 111.740 1.00 101.83 ? 507  ARG A NH2 1 
ATOM   3052 N  N   . GLN A 1 508 ? 191.261 171.106 114.672 1.00 101.34 ? 508  GLN A N   1 
ATOM   3053 C  CA  . GLN A 1 508 ? 191.141 172.450 115.223 1.00 101.34 ? 508  GLN A CA  1 
ATOM   3054 C  C   . GLN A 1 508 ? 189.832 172.620 115.985 1.00 101.34 ? 508  GLN A C   1 
ATOM   3055 O  O   . GLN A 1 508 ? 189.764 173.404 116.939 1.00 101.34 ? 508  GLN A O   1 
ATOM   3056 C  CB  . GLN A 1 508 ? 191.255 173.483 114.098 1.00 101.34 ? 508  GLN A CB  1 
ATOM   3057 C  CG  . GLN A 1 508 ? 190.728 174.870 114.434 1.00 101.34 ? 508  GLN A CG  1 
ATOM   3058 C  CD  . GLN A 1 508 ? 191.817 175.820 114.887 1.00 101.34 ? 508  GLN A CD  1 
ATOM   3059 O  OE1 . GLN A 1 508 ? 192.925 175.814 114.352 1.00 101.34 ? 508  GLN A OE1 1 
ATOM   3060 N  NE2 . GLN A 1 508 ? 191.505 176.648 115.878 1.00 101.34 ? 508  GLN A NE2 1 
ATOM   3061 N  N   . GLY A 1 509 ? 188.798 171.874 115.605 1.00 100.64 ? 509  GLY A N   1 
ATOM   3062 C  CA  . GLY A 1 509 ? 187.469 172.049 116.150 1.00 100.64 ? 509  GLY A CA  1 
ATOM   3063 C  C   . GLY A 1 509 ? 186.507 172.750 115.221 1.00 100.64 ? 509  GLY A C   1 
ATOM   3064 O  O   . GLY A 1 509 ? 185.594 173.430 115.701 1.00 100.64 ? 509  GLY A O   1 
ATOM   3065 N  N   . LEU A 1 510 ? 186.682 172.602 113.914 1.00 103.09 ? 510  LEU A N   1 
ATOM   3066 C  CA  . LEU A 1 510 ? 186.035 173.455 112.933 1.00 103.09 ? 510  LEU A CA  1 
ATOM   3067 C  C   . LEU A 1 510 ? 185.110 172.615 112.061 1.00 103.09 ? 510  LEU A C   1 
ATOM   3068 O  O   . LEU A 1 510 ? 185.560 171.676 111.398 1.00 103.09 ? 510  LEU A O   1 
ATOM   3069 C  CB  . LEU A 1 510 ? 187.115 174.140 112.095 1.00 103.09 ? 510  LEU A CB  1 
ATOM   3070 C  CG  . LEU A 1 510 ? 187.261 175.661 112.107 1.00 103.09 ? 510  LEU A CG  1 
ATOM   3071 C  CD1 . LEU A 1 510 ? 188.140 176.114 110.960 1.00 103.09 ? 510  LEU A CD1 1 
ATOM   3072 C  CD2 . LEU A 1 510 ? 185.920 176.340 112.037 1.00 103.09 ? 510  LEU A CD2 1 
ATOM   3073 N  N   . ARG A 1 511 ? 183.821 172.950 112.062 1.00 102.41 ? 511  ARG A N   1 
ATOM   3074 C  CA  . ARG A 1 511 ? 182.846 172.216 111.264 1.00 102.41 ? 511  ARG A CA  1 
ATOM   3075 C  C   . ARG A 1 511 ? 183.033 172.570 109.796 1.00 102.41 ? 511  ARG A C   1 
ATOM   3076 O  O   . ARG A 1 511 ? 182.747 173.699 109.384 1.00 102.41 ? 511  ARG A O   1 
ATOM   3077 C  CB  . ARG A 1 511 ? 181.422 172.540 111.712 1.00 102.41 ? 511  ARG A CB  1 
ATOM   3078 C  CG  . ARG A 1 511 ? 180.996 171.863 113.004 1.00 102.41 ? 511  ARG A CG  1 
ATOM   3079 C  CD  . ARG A 1 511 ? 179.556 172.202 113.385 1.00 102.41 ? 511  ARG A CD  1 
ATOM   3080 N  NE  . ARG A 1 511 ? 178.755 172.666 112.257 1.00 102.41 ? 511  ARG A NE  1 
ATOM   3081 C  CZ  . ARG A 1 511 ? 178.178 171.871 111.365 1.00 102.41 ? 511  ARG A CZ  1 
ATOM   3082 N  NH1 . ARG A 1 511 ? 178.289 170.555 111.438 1.00 102.41 ? 511  ARG A NH1 1 
ATOM   3083 N  NH2 . ARG A 1 511 ? 177.471 172.410 110.377 1.00 102.41 ? 511  ARG A NH2 1 
ATOM   3084 N  N   . VAL A 1 512 ? 183.508 171.612 109.008 1.00 112.59 ? 512  VAL A N   1 
ATOM   3085 C  CA  . VAL A 1 512 ? 183.823 171.841 107.604 1.00 112.59 ? 512  VAL A CA  1 
ATOM   3086 C  C   . VAL A 1 512 ? 182.579 171.580 106.766 1.00 112.59 ? 512  VAL A C   1 
ATOM   3087 O  O   . VAL A 1 512 ? 181.846 170.612 107.005 1.00 112.59 ? 512  VAL A O   1 
ATOM   3088 C  CB  . VAL A 1 512 ? 185.007 170.968 107.146 1.00 112.59 ? 512  VAL A CB  1 
ATOM   3089 C  CG1 . VAL A 1 512 ? 184.622 169.496 107.085 1.00 112.59 ? 512  VAL A CG1 1 
ATOM   3090 C  CG2 . VAL A 1 512 ? 185.522 171.442 105.798 1.00 112.59 ? 512  VAL A CG2 1 
ATOM   3091 N  N   . VAL A 1 513 ? 182.313 172.476 105.820 1.00 123.53 ? 513  VAL A N   1 
ATOM   3092 C  CA  . VAL A 1 513 ? 181.260 172.304 104.827 1.00 123.53 ? 513  VAL A CA  1 
ATOM   3093 C  C   . VAL A 1 513 ? 181.858 172.640 103.471 1.00 123.53 ? 513  VAL A C   1 
ATOM   3094 O  O   . VAL A 1 513 ? 182.336 173.761 103.261 1.00 123.53 ? 513  VAL A O   1 
ATOM   3095 C  CB  . VAL A 1 513 ? 180.034 173.187 105.112 1.00 123.53 ? 513  VAL A CB  1 
ATOM   3096 C  CG1 . VAL A 1 513 ? 178.998 173.015 104.018 1.00 123.53 ? 513  VAL A CG1 1 
ATOM   3097 C  CG2 . VAL A 1 513 ? 179.431 172.843 106.463 1.00 123.53 ? 513  VAL A CG2 1 
ATOM   3098 N  N   . ALA A 1 514 ? 181.832 171.679 102.556 1.00 138.65 ? 514  ALA A N   1 
ATOM   3099 C  CA  . ALA A 1 514 ? 182.412 171.867 101.237 1.00 138.65 ? 514  ALA A CA  1 
ATOM   3100 C  C   . ALA A 1 514 ? 181.367 172.399 100.266 1.00 138.65 ? 514  ALA A C   1 
ATOM   3101 O  O   . ALA A 1 514 ? 180.200 171.999 100.296 1.00 138.65 ? 514  ALA A O   1 
ATOM   3102 C  CB  . ALA A 1 514 ? 182.996 170.557 100.710 1.00 138.65 ? 514  ALA A CB  1 
ATOM   3103 N  N   . VAL A 1 515 ? 181.800 173.308 99.398  1.00 147.19 ? 515  VAL A N   1 
ATOM   3104 C  CA  . VAL A 1 515 ? 180.933 173.936 98.410  1.00 147.19 ? 515  VAL A CA  1 
ATOM   3105 C  C   . VAL A 1 515 ? 181.320 173.419 97.032  1.00 147.19 ? 515  VAL A C   1 
ATOM   3106 O  O   . VAL A 1 515 ? 182.508 173.240 96.738  1.00 147.19 ? 515  VAL A O   1 
ATOM   3107 C  CB  . VAL A 1 515 ? 181.005 175.474 98.479  1.00 147.19 ? 515  VAL A CB  1 
ATOM   3108 C  CG1 . VAL A 1 515 ? 182.338 175.994 97.959  1.00 147.19 ? 515  VAL A CG1 1 
ATOM   3109 C  CG2 . VAL A 1 515 ? 179.852 176.089 97.704  1.00 147.19 ? 515  VAL A CG2 1 
ATOM   3110 N  N   . ALA A 1 516 ? 180.316 173.137 96.208  1.00 157.49 ? 516  ALA A N   1 
ATOM   3111 C  CA  . ALA A 1 516 ? 180.526 172.620 94.867  1.00 157.49 ? 516  ALA A CA  1 
ATOM   3112 C  C   . ALA A 1 516 ? 179.726 173.444 93.870  1.00 157.49 ? 516  ALA A C   1 
ATOM   3113 O  O   . ALA A 1 516 ? 178.653 173.962 94.189  1.00 157.49 ? 516  ALA A O   1 
ATOM   3114 C  CB  . ALA A 1 516 ? 180.125 171.144 94.762  1.00 157.49 ? 516  ALA A CB  1 
ATOM   3115 N  N   . THR A 1 517 ? 180.260 173.558 92.657  1.00 165.14 ? 517  THR A N   1 
ATOM   3116 C  CA  . THR A 1 517 ? 179.631 174.318 91.589  1.00 165.14 ? 517  THR A CA  1 
ATOM   3117 C  C   . THR A 1 517 ? 179.677 173.512 90.298  1.00 165.14 ? 517  THR A C   1 
ATOM   3118 O  O   . THR A 1 517 ? 180.515 172.624 90.118  1.00 165.14 ? 517  THR A O   1 
ATOM   3119 C  CB  . THR A 1 517 ? 180.310 175.681 91.391  1.00 165.14 ? 517  THR A CB  1 
ATOM   3120 O  OG1 . THR A 1 517 ? 179.568 176.452 90.438  1.00 165.14 ? 517  THR A OG1 1 
ATOM   3121 C  CG2 . THR A 1 517 ? 181.736 175.501 90.894  1.00 165.14 ? 517  THR A CG2 1 
ATOM   3122 N  N   . LYS A 1 518 ? 178.753 173.828 89.395  1.00 166.69 ? 518  LYS A N   1 
ATOM   3123 C  CA  . LYS A 1 518 ? 178.689 173.157 88.105  1.00 166.69 ? 518  LYS A CA  1 
ATOM   3124 C  C   . LYS A 1 518 ? 178.029 174.089 87.102  1.00 166.69 ? 518  LYS A C   1 
ATOM   3125 O  O   . LYS A 1 518 ? 177.145 174.875 87.453  1.00 166.69 ? 518  LYS A O   1 
ATOM   3126 C  CB  . LYS A 1 518 ? 177.919 171.834 88.196  1.00 166.69 ? 518  LYS A CB  1 
ATOM   3127 C  CG  . LYS A 1 518 ? 178.043 170.956 86.962  1.00 166.69 ? 518  LYS A CG  1 
ATOM   3128 C  CD  . LYS A 1 518 ? 177.012 169.841 86.967  1.00 166.69 ? 518  LYS A CD  1 
ATOM   3129 C  CE  . LYS A 1 518 ? 177.189 168.923 85.769  1.00 166.69 ? 518  LYS A CE  1 
ATOM   3130 N  NZ  . LYS A 1 518 ? 176.240 167.776 85.804  1.00 166.69 ? 518  LYS A NZ  1 
ATOM   3131 N  N   . TYR A 1 519 ? 178.468 173.992 85.851  1.00 171.08 ? 519  TYR A N   1 
ATOM   3132 C  CA  . TYR A 1 519 ? 177.928 174.789 84.759  1.00 171.08 ? 519  TYR A CA  1 
ATOM   3133 C  C   . TYR A 1 519 ? 177.150 173.883 83.815  1.00 171.08 ? 519  TYR A C   1 
ATOM   3134 O  O   . TYR A 1 519 ? 177.690 172.891 83.314  1.00 171.08 ? 519  TYR A O   1 
ATOM   3135 C  CB  . TYR A 1 519 ? 179.043 175.514 84.003  1.00 171.08 ? 519  TYR A CB  1 
ATOM   3136 C  CG  . TYR A 1 519 ? 179.571 176.736 84.720  1.00 171.08 ? 519  TYR A CG  1 
ATOM   3137 C  CD1 . TYR A 1 519 ? 180.715 177.386 84.274  1.00 171.08 ? 519  TYR A CD1 1 
ATOM   3138 C  CD2 . TYR A 1 519 ? 178.925 177.241 85.840  1.00 171.08 ? 519  TYR A CD2 1 
ATOM   3139 C  CE1 . TYR A 1 519 ? 181.201 178.503 84.925  1.00 171.08 ? 519  TYR A CE1 1 
ATOM   3140 C  CE2 . TYR A 1 519 ? 179.403 178.358 86.498  1.00 171.08 ? 519  TYR A CE2 1 
ATOM   3141 C  CZ  . TYR A 1 519 ? 180.541 178.985 86.036  1.00 171.08 ? 519  TYR A CZ  1 
ATOM   3142 O  OH  . TYR A 1 519 ? 181.020 180.097 86.688  1.00 171.08 ? 519  TYR A OH  1 
ATOM   3143 N  N   . LEU A 1 520 ? 175.889 174.226 83.577  1.00 172.94 ? 520  LEU A N   1 
ATOM   3144 C  CA  . LEU A 1 520 ? 175.016 173.453 82.712  1.00 172.94 ? 520  LEU A CA  1 
ATOM   3145 C  C   . LEU A 1 520 ? 174.311 174.375 81.730  1.00 172.94 ? 520  LEU A C   1 
ATOM   3146 O  O   . LEU A 1 520 ? 174.074 175.549 82.034  1.00 172.94 ? 520  LEU A O   1 
ATOM   3147 C  CB  . LEU A 1 520 ? 173.972 172.679 83.531  1.00 172.94 ? 520  LEU A CB  1 
ATOM   3148 N  N   . PRO A 1 521 ? 173.971 173.875 80.544  1.00 175.42 ? 521  PRO A N   1 
ATOM   3149 C  CA  . PRO A 1 521 ? 173.222 174.697 79.590  1.00 175.42 ? 521  PRO A CA  1 
ATOM   3150 C  C   . PRO A 1 521 ? 171.827 175.009 80.104  1.00 175.42 ? 521  PRO A C   1 
ATOM   3151 O  O   . PRO A 1 521 ? 171.231 174.242 80.865  1.00 175.42 ? 521  PRO A O   1 
ATOM   3152 C  CB  . PRO A 1 521 ? 173.169 173.826 78.329  1.00 175.42 ? 521  PRO A CB  1 
ATOM   3153 C  CG  . PRO A 1 521 ? 173.377 172.432 78.819  1.00 175.42 ? 521  PRO A CG  1 
ATOM   3154 C  CD  . PRO A 1 521 ? 174.293 172.545 79.999  1.00 175.42 ? 521  PRO A CD  1 
ATOM   3155 N  N   . ALA A 1 522 ? 171.311 176.162 79.682  1.00 174.84 ? 522  ALA A N   1 
ATOM   3156 C  CA  . ALA A 1 522 ? 169.980 176.579 80.099  1.00 174.84 ? 522  ALA A CA  1 
ATOM   3157 C  C   . ALA A 1 522 ? 168.927 175.612 79.574  1.00 174.84 ? 522  ALA A C   1 
ATOM   3158 O  O   . ALA A 1 522 ? 168.986 175.164 78.425  1.00 174.84 ? 522  ALA A O   1 
ATOM   3159 C  CB  . ALA A 1 522 ? 169.690 177.997 79.606  1.00 174.84 ? 522  ALA A CB  1 
ATOM   3160 N  N   . ARG A 1 523 ? 167.956 175.291 80.426  1.00 176.37 ? 523  ARG A N   1 
ATOM   3161 C  CA  . ARG A 1 523 ? 166.890 174.371 80.061  1.00 176.37 ? 523  ARG A CA  1 
ATOM   3162 C  C   . ARG A 1 523 ? 165.624 174.757 80.809  1.00 176.37 ? 523  ARG A C   1 
ATOM   3163 O  O   . ARG A 1 523 ? 165.668 175.433 81.840  1.00 176.37 ? 523  ARG A O   1 
ATOM   3164 C  CB  . ARG A 1 523 ? 167.272 172.917 80.364  1.00 176.37 ? 523  ARG A CB  1 
ATOM   3165 N  N   . GLU A 1 524 ? 164.486 174.317 80.272  1.00 174.71 ? 524  GLU A N   1 
ATOM   3166 C  CA  . GLU A 1 524 ? 163.188 174.598 80.867  1.00 174.71 ? 524  GLU A CA  1 
ATOM   3167 C  C   . GLU A 1 524 ? 162.745 173.539 81.868  1.00 174.71 ? 524  GLU A C   1 
ATOM   3168 O  O   . GLU A 1 524 ? 161.690 173.702 82.489  1.00 174.71 ? 524  GLU A O   1 
ATOM   3169 C  CB  . GLU A 1 524 ? 162.122 174.738 79.773  1.00 174.71 ? 524  GLU A CB  1 
ATOM   3170 N  N   . GLY A 1 525 ? 163.517 172.468 82.040  1.00 173.24 ? 525  GLY A N   1 
ATOM   3171 C  CA  . GLY A 1 525 ? 163.167 171.424 82.976  1.00 173.24 ? 525  GLY A CA  1 
ATOM   3172 C  C   . GLY A 1 525 ? 163.464 171.808 84.412  1.00 173.24 ? 525  GLY A C   1 
ATOM   3173 O  O   . GLY A 1 525 ? 164.074 172.834 84.710  1.00 173.24 ? 525  GLY A O   1 
ATOM   3174 N  N   . ASP A 1 526 ? 163.016 170.949 85.323  1.00 171.49 ? 526  ASP A N   1 
ATOM   3175 C  CA  . ASP A 1 526 ? 163.217 171.143 86.751  1.00 171.49 ? 526  ASP A CA  1 
ATOM   3176 C  C   . ASP A 1 526 ? 164.367 170.265 87.225  1.00 171.49 ? 526  ASP A C   1 
ATOM   3177 O  O   . ASP A 1 526 ? 164.334 169.042 87.051  1.00 171.49 ? 526  ASP A O   1 
ATOM   3178 C  CB  . ASP A 1 526 ? 161.944 170.815 87.532  1.00 171.49 ? 526  ASP A CB  1 
ATOM   3179 N  N   . TYR A 1 527 ? 165.379 170.892 87.819  1.00 168.08 ? 527  TYR A N   1 
ATOM   3180 C  CA  . TYR A 1 527 ? 166.536 170.152 88.305  1.00 168.08 ? 527  TYR A CA  1 
ATOM   3181 C  C   . TYR A 1 527 ? 166.142 169.278 89.488  1.00 168.08 ? 527  TYR A C   1 
ATOM   3182 O  O   . TYR A 1 527 ? 165.400 169.710 90.376  1.00 168.08 ? 527  TYR A O   1 
ATOM   3183 C  CB  . TYR A 1 527 ? 167.652 171.115 88.704  1.00 168.08 ? 527  TYR A CB  1 
ATOM   3184 N  N   . GLN A 1 528 ? 166.637 168.047 89.497  1.00 164.52 ? 528  GLN A N   1 
ATOM   3185 C  CA  . GLN A 1 528 ? 166.364 167.084 90.554  1.00 164.52 ? 528  GLN A CA  1 
ATOM   3186 C  C   . GLN A 1 528 ? 167.667 166.717 91.257  1.00 164.52 ? 528  GLN A C   1 
ATOM   3187 O  O   . GLN A 1 528 ? 168.731 167.275 90.978  1.00 164.52 ? 528  GLN A O   1 
ATOM   3188 C  CB  . GLN A 1 528 ? 165.673 165.839 89.990  1.00 164.52 ? 528  GLN A CB  1 
ATOM   3189 N  N   . ARG A 1 529 ? 167.570 165.763 92.186  1.00 165.46 ? 529  ARG A N   1 
ATOM   3190 C  CA  . ARG A 1 529 ? 168.751 165.299 92.903  1.00 165.46 ? 529  ARG A CA  1 
ATOM   3191 C  C   . ARG A 1 529 ? 169.757 164.620 91.982  1.00 165.46 ? 529  ARG A C   1 
ATOM   3192 O  O   . ARG A 1 529 ? 170.955 164.624 92.285  1.00 165.46 ? 529  ARG A O   1 
ATOM   3193 C  CB  . ARG A 1 529 ? 168.343 164.342 94.023  1.00 165.46 ? 529  ARG A CB  1 
ATOM   3194 N  N   . ALA A 1 530 ? 169.300 164.040 90.870  1.00 164.41 ? 530  ALA A N   1 
ATOM   3195 C  CA  . ALA A 1 530 ? 170.211 163.394 89.934  1.00 164.41 ? 530  ALA A CA  1 
ATOM   3196 C  C   . ALA A 1 530 ? 171.108 164.391 89.213  1.00 164.41 ? 530  ALA A C   1 
ATOM   3197 O  O   . ALA A 1 530 ? 172.168 164.000 88.712  1.00 164.41 ? 530  ALA A O   1 
ATOM   3198 C  CB  . ALA A 1 530 ? 169.423 162.573 88.913  1.00 164.41 ? 530  ALA A CB  1 
ATOM   3199 N  N   . ASP A 1 531 ? 170.712 165.663 89.149  1.00 164.35 ? 531  ASP A N   1 
ATOM   3200 C  CA  . ASP A 1 531 ? 171.529 166.675 88.491  1.00 164.35 ? 531  ASP A CA  1 
ATOM   3201 C  C   . ASP A 1 531 ? 172.810 166.986 89.251  1.00 164.35 ? 531  ASP A C   1 
ATOM   3202 O  O   . ASP A 1 531 ? 173.723 167.584 88.671  1.00 164.35 ? 531  ASP A O   1 
ATOM   3203 C  CB  . ASP A 1 531 ? 170.718 167.958 88.299  1.00 164.35 ? 531  ASP A CB  1 
ATOM   3204 N  N   . GLU A 1 532 ? 172.904 166.597 90.523  1.00 165.28 ? 532  GLU A N   1 
ATOM   3205 C  CA  . GLU A 1 532 ? 174.097 166.849 91.331  1.00 165.28 ? 532  GLU A CA  1 
ATOM   3206 C  C   . GLU A 1 532 ? 175.129 165.752 91.065  1.00 165.28 ? 532  GLU A C   1 
ATOM   3207 O  O   . GLU A 1 532 ? 175.404 164.883 91.894  1.00 165.28 ? 532  GLU A O   1 
ATOM   3208 C  CB  . GLU A 1 532 ? 173.733 166.932 92.807  1.00 165.28 ? 532  GLU A CB  1 
ATOM   3209 N  N   . SER A 1 533 ? 175.704 165.805 89.866  1.00 164.42 ? 533  SER A N   1 
ATOM   3210 C  CA  . SER A 1 533 ? 176.718 164.848 89.450  1.00 164.42 ? 533  SER A CA  1 
ATOM   3211 C  C   . SER A 1 533 ? 177.796 165.568 88.655  1.00 164.42 ? 533  SER A C   1 
ATOM   3212 O  O   . SER A 1 533 ? 177.522 166.546 87.954  1.00 164.42 ? 533  SER A O   1 
ATOM   3213 C  CB  . SER A 1 533 ? 176.114 163.714 88.611  1.00 164.42 ? 533  SER A CB  1 
ATOM   3214 N  N   . ASP A 1 534 ? 179.027 165.067 88.773  1.00 164.23 ? 534  ASP A N   1 
ATOM   3215 C  CA  . ASP A 1 534 ? 180.183 165.622 88.066  1.00 164.23 ? 534  ASP A CA  1 
ATOM   3216 C  C   . ASP A 1 534 ? 180.359 167.108 88.370  1.00 164.23 ? 534  ASP A C   1 
ATOM   3217 O  O   . ASP A 1 534 ? 180.718 167.907 87.502  1.00 164.23 ? 534  ASP A O   1 
ATOM   3218 C  CB  . ASP A 1 534 ? 180.073 165.383 86.559  1.00 164.23 ? 534  ASP A CB  1 
ATOM   3219 N  N   . LEU A 1 535 ? 180.102 167.483 89.620  1.00 164.22 ? 535  LEU A N   1 
ATOM   3220 C  CA  . LEU A 1 535 ? 180.235 168.871 90.027  1.00 164.22 ? 535  LEU A CA  1 
ATOM   3221 C  C   . LEU A 1 535 ? 181.694 169.209 90.324  1.00 164.22 ? 535  LEU A C   1 
ATOM   3222 O  O   . LEU A 1 535 ? 182.543 168.332 90.499  1.00 164.22 ? 535  LEU A O   1 
ATOM   3223 C  CB  . LEU A 1 535 ? 179.369 169.156 91.254  1.00 164.22 ? 535  LEU A CB  1 
ATOM   3224 N  N   . ILE A 1 536 ? 181.978 170.508 90.377  1.00 161.55 ? 536  ILE A N   1 
ATOM   3225 C  CA  . ILE A 1 536 ? 183.314 171.014 90.663  1.00 161.55 ? 536  ILE A CA  1 
ATOM   3226 C  C   . ILE A 1 536 ? 183.331 171.564 92.081  1.00 161.55 ? 536  ILE A C   1 
ATOM   3227 O  O   . ILE A 1 536 ? 182.549 172.462 92.416  1.00 161.55 ? 536  ILE A O   1 
ATOM   3228 C  CB  . ILE A 1 536 ? 183.733 172.092 89.649  1.00 161.55 ? 536  ILE A CB  1 
ATOM   3229 N  N   . LEU A 1 537 ? 184.227 171.033 92.912  1.00 154.47 ? 537  LEU A N   1 
ATOM   3230 C  CA  . LEU A 1 537 ? 184.334 171.439 94.313  1.00 154.47 ? 537  LEU A CA  1 
ATOM   3231 C  C   . LEU A 1 537 ? 185.204 172.687 94.386  1.00 154.47 ? 537  LEU A C   1 
ATOM   3232 O  O   . LEU A 1 537 ? 186.434 172.606 94.337  1.00 154.47 ? 537  LEU A O   1 
ATOM   3233 C  CB  . LEU A 1 537 ? 184.908 170.308 95.160  1.00 154.47 ? 537  LEU A CB  1 
ATOM   3234 N  N   . GLU A 1 538 ? 184.560 173.850 94.500  1.00 147.17 ? 538  GLU A N   1 
ATOM   3235 C  CA  . GLU A 1 538 ? 185.300 175.106 94.564  1.00 147.17 ? 538  GLU A CA  1 
ATOM   3236 C  C   . GLU A 1 538 ? 186.144 175.192 95.830  1.00 147.17 ? 538  GLU A C   1 
ATOM   3237 O  O   . GLU A 1 538 ? 187.286 175.664 95.790  1.00 147.17 ? 538  GLU A O   1 
ATOM   3238 C  CB  . GLU A 1 538 ? 184.335 176.288 94.481  1.00 147.17 ? 538  GLU A CB  1 
ATOM   3239 N  N   . GLY A 1 539 ? 185.602 174.746 96.957  1.00 139.77 ? 539  GLY A N   1 
ATOM   3240 C  CA  . GLY A 1 539 ? 186.320 174.829 98.210  1.00 139.77 ? 539  GLY A CA  1 
ATOM   3241 C  C   . GLY A 1 539 ? 185.453 174.346 99.356  1.00 139.77 ? 539  GLY A C   1 
ATOM   3242 O  O   . GLY A 1 539 ? 184.405 173.730 99.151  1.00 139.77 ? 539  GLY A O   1 
ATOM   3243 N  N   . TYR A 1 540 ? 185.917 174.640 100.568 1.00 127.24 ? 540  TYR A N   1 
ATOM   3244 C  CA  . TYR A 1 540 ? 185.228 174.240 101.785 1.00 127.24 ? 540  TYR A CA  1 
ATOM   3245 C  C   . TYR A 1 540 ? 185.074 175.441 102.706 1.00 127.24 ? 540  TYR A C   1 
ATOM   3246 O  O   . TYR A 1 540 ? 185.988 176.261 102.829 1.00 127.24 ? 540  TYR A O   1 
ATOM   3247 C  CB  . TYR A 1 540 ? 185.984 173.119 102.507 1.00 127.24 ? 540  TYR A CB  1 
ATOM   3248 N  N   . ILE A 1 541 ? 183.916 175.541 103.351 1.00 116.16 ? 541  ILE A N   1 
ATOM   3249 C  CA  . ILE A 1 541 ? 183.662 176.580 104.336 1.00 116.16 ? 541  ILE A CA  1 
ATOM   3250 C  C   . ILE A 1 541 ? 183.687 175.938 105.715 1.00 116.16 ? 541  ILE A C   1 
ATOM   3251 O  O   . ILE A 1 541 ? 183.284 174.786 105.903 1.00 116.16 ? 541  ILE A O   1 
ATOM   3252 C  CB  . ILE A 1 541 ? 182.324 177.307 104.092 1.00 116.16 ? 541  ILE A CB  1 
ATOM   3253 C  CG1 . ILE A 1 541 ? 182.153 177.627 102.610 1.00 116.16 ? 541  ILE A CG1 1 
ATOM   3254 C  CG2 . ILE A 1 541 ? 182.268 178.592 104.894 1.00 116.16 ? 541  ILE A CG2 1 
ATOM   3255 C  CD1 . ILE A 1 541 ? 183.078 178.712 102.117 1.00 116.16 ? 541  ILE A CD1 1 
ATOM   3256 N  N   . ALA A 1 542 ? 184.164 176.700 106.695 1.00 107.17 ? 542  ALA A N   1 
ATOM   3257 C  CA  . ALA A 1 542 ? 184.406 176.172 108.027 1.00 107.17 ? 542  ALA A CA  1 
ATOM   3258 C  C   . ALA A 1 542 ? 183.683 177.008 109.073 1.00 107.17 ? 542  ALA A C   1 
ATOM   3259 O  O   . ALA A 1 542 ? 183.690 178.240 109.015 1.00 107.17 ? 542  ALA A O   1 
ATOM   3260 C  CB  . ALA A 1 542 ? 185.900 176.126 108.326 1.00 107.17 ? 542  ALA A CB  1 
ATOM   3261 N  N   . PHE A 1 543 ? 183.071 176.323 110.033 1.00 101.15 ? 543  PHE A N   1 
ATOM   3262 C  CA  . PHE A 1 543 ? 182.268 176.936 111.078 1.00 101.15 ? 543  PHE A CA  1 
ATOM   3263 C  C   . PHE A 1 543 ? 182.643 176.339 112.428 1.00 101.15 ? 543  PHE A C   1 
ATOM   3264 O  O   . PHE A 1 543 ? 183.020 175.168 112.515 1.00 101.15 ? 543  PHE A O   1 
ATOM   3265 C  CB  . PHE A 1 543 ? 180.782 176.716 110.811 1.00 101.15 ? 543  PHE A CB  1 
ATOM   3266 C  CG  . PHE A 1 543 ? 180.345 177.104 109.433 1.00 101.15 ? 543  PHE A CG  1 
ATOM   3267 C  CD1 . PHE A 1 543 ? 180.493 178.404 108.984 1.00 101.15 ? 543  PHE A CD1 1 
ATOM   3268 C  CD2 . PHE A 1 543 ? 179.796 176.165 108.580 1.00 101.15 ? 543  PHE A CD2 1 
ATOM   3269 C  CE1 . PHE A 1 543 ? 180.086 178.764 107.717 1.00 101.15 ? 543  PHE A CE1 1 
ATOM   3270 C  CE2 . PHE A 1 543 ? 179.390 176.518 107.314 1.00 101.15 ? 543  PHE A CE2 1 
ATOM   3271 C  CZ  . PHE A 1 543 ? 179.535 177.818 106.880 1.00 101.15 ? 543  PHE A CZ  1 
ATOM   3272 N  N   . LEU A 1 544 ? 182.548 177.144 113.486 1.00 91.76  ? 544  LEU A N   1 
ATOM   3273 C  CA  . LEU A 1 544 ? 182.919 176.689 114.820 1.00 91.76  ? 544  LEU A CA  1 
ATOM   3274 C  C   . LEU A 1 544 ? 181.871 177.097 115.847 1.00 91.76  ? 544  LEU A C   1 
ATOM   3275 O  O   . LEU A 1 544 ? 181.226 178.141 115.724 1.00 91.76  ? 544  LEU A O   1 
ATOM   3276 C  CB  . LEU A 1 544 ? 184.291 177.234 115.250 1.00 91.76  ? 544  LEU A CB  1 
ATOM   3277 C  CG  . LEU A 1 544 ? 184.348 178.632 115.866 1.00 91.76  ? 544  LEU A CG  1 
ATOM   3278 C  CD1 . LEU A 1 544 ? 185.635 178.810 116.651 1.00 91.76  ? 544  LEU A CD1 1 
ATOM   3279 C  CD2 . LEU A 1 544 ? 184.222 179.700 114.801 1.00 91.76  ? 544  LEU A CD2 1 
ATOM   3280 N  N   . ASP A 1 545 ? 181.715 176.254 116.866 1.00 80.66  ? 545  ASP A N   1 
ATOM   3281 C  CA  . ASP A 1 545 ? 180.821 176.515 117.989 1.00 80.66  ? 545  ASP A CA  1 
ATOM   3282 C  C   . ASP A 1 545 ? 181.639 176.833 119.229 1.00 80.66  ? 545  ASP A C   1 
ATOM   3283 O  O   . ASP A 1 545 ? 182.315 175.939 119.760 1.00 80.66  ? 545  ASP A O   1 
ATOM   3284 C  CB  . ASP A 1 545 ? 179.915 175.313 118.254 1.00 80.66  ? 545  ASP A CB  1 
ATOM   3285 C  CG  . ASP A 1 545 ? 178.824 175.166 117.222 1.00 80.66  ? 545  ASP A CG  1 
ATOM   3286 O  OD1 . ASP A 1 545 ? 178.363 176.201 116.704 1.00 80.66  ? 545  ASP A OD1 1 
ATOM   3287 O  OD2 . ASP A 1 545 ? 178.427 174.019 116.930 1.00 80.66  ? 545  ASP A OD2 1 
ATOM   3288 N  N   . PRO A 1 546 ? 181.621 178.064 119.725 1.00 71.80  ? 546  PRO A N   1 
ATOM   3289 C  CA  . PRO A 1 546 ? 182.338 178.372 120.963 1.00 71.80  ? 546  PRO A CA  1 
ATOM   3290 C  C   . PRO A 1 546 ? 181.670 177.705 122.150 1.00 71.80  ? 546  PRO A C   1 
ATOM   3291 O  O   . PRO A 1 546 ? 180.458 177.860 122.357 1.00 71.80  ? 546  PRO A O   1 
ATOM   3292 C  CB  . PRO A 1 546 ? 182.243 179.902 121.055 1.00 71.80  ? 546  PRO A CB  1 
ATOM   3293 C  CG  . PRO A 1 546 ? 181.027 180.248 120.270 1.00 71.80  ? 546  PRO A CG  1 
ATOM   3294 C  CD  . PRO A 1 546 ? 180.966 179.249 119.150 1.00 71.80  ? 546  PRO A CD  1 
ATOM   3295 N  N   . PRO A 1 547 ? 182.421 176.947 122.947 1.00 63.05  ? 547  PRO A N   1 
ATOM   3296 C  CA  . PRO A 1 547 ? 181.824 176.297 124.116 1.00 63.05  ? 547  PRO A CA  1 
ATOM   3297 C  C   . PRO A 1 547 ? 181.257 177.319 125.088 1.00 63.05  ? 547  PRO A C   1 
ATOM   3298 O  O   . PRO A 1 547 ? 181.753 178.442 125.202 1.00 63.05  ? 547  PRO A O   1 
ATOM   3299 C  CB  . PRO A 1 547 ? 182.998 175.529 124.731 1.00 63.05  ? 547  PRO A CB  1 
ATOM   3300 C  CG  . PRO A 1 547 ? 183.920 175.296 123.588 1.00 63.05  ? 547  PRO A CG  1 
ATOM   3301 C  CD  . PRO A 1 547 ? 183.814 176.525 122.736 1.00 63.05  ? 547  PRO A CD  1 
ATOM   3302 N  N   . LYS A 1 548 ? 180.194 176.919 125.782 1.00 59.91  ? 548  LYS A N   1 
ATOM   3303 C  CA  . LYS A 1 548 ? 179.515 177.821 126.701 1.00 59.91  ? 548  LYS A CA  1 
ATOM   3304 C  C   . LYS A 1 548 ? 180.470 178.302 127.785 1.00 59.91  ? 548  LYS A C   1 
ATOM   3305 O  O   . LYS A 1 548 ? 181.314 177.548 128.275 1.00 59.91  ? 548  LYS A O   1 
ATOM   3306 C  CB  . LYS A 1 548 ? 178.311 177.124 127.335 1.00 59.91  ? 548  LYS A CB  1 
ATOM   3307 C  CG  . LYS A 1 548 ? 177.227 176.740 126.346 1.00 59.91  ? 548  LYS A CG  1 
ATOM   3308 C  CD  . LYS A 1 548 ? 176.158 175.874 126.990 1.00 59.91  ? 548  LYS A CD  1 
ATOM   3309 C  CE  . LYS A 1 548 ? 175.225 176.697 127.854 1.00 59.91  ? 548  LYS A CE  1 
ATOM   3310 N  NZ  . LYS A 1 548 ? 174.337 177.559 127.031 1.00 59.91  ? 548  LYS A NZ  1 
ATOM   3311 N  N   . GLU A 1 549 ? 180.343 179.581 128.146 1.00 65.00  ? 549  GLU A N   1 
ATOM   3312 C  CA  . GLU A 1 549 ? 181.190 180.138 129.194 1.00 65.00  ? 549  GLU A CA  1 
ATOM   3313 C  C   . GLU A 1 549 ? 180.872 179.525 130.551 1.00 65.00  ? 549  GLU A C   1 
ATOM   3314 O  O   . GLU A 1 549 ? 181.761 179.399 131.401 1.00 65.00  ? 549  GLU A O   1 
ATOM   3315 C  CB  . GLU A 1 549 ? 181.037 181.660 129.252 1.00 65.00  ? 549  GLU A CB  1 
ATOM   3316 C  CG  . GLU A 1 549 ? 181.213 182.383 127.918 1.00 65.00  ? 549  GLU A CG  1 
ATOM   3317 C  CD  . GLU A 1 549 ? 179.992 182.288 127.019 1.00 65.00  ? 549  GLU A CD  1 
ATOM   3318 O  OE1 . GLU A 1 549 ? 180.166 182.136 125.792 1.00 65.00  ? 549  GLU A OE1 1 
ATOM   3319 O  OE2 . GLU A 1 549 ? 178.860 182.363 127.540 1.00 65.00  ? 549  GLU A OE2 1 
ATOM   3320 N  N   . THR A 1 550 ? 179.617 179.141 130.772 1.00 59.95  ? 550  THR A N   1 
ATOM   3321 C  CA  . THR A 1 550 ? 179.190 178.546 132.029 1.00 59.95  ? 550  THR A CA  1 
ATOM   3322 C  C   . THR A 1 550 ? 179.513 177.061 132.128 1.00 59.95  ? 550  THR A C   1 
ATOM   3323 O  O   . THR A 1 550 ? 179.483 176.507 133.232 1.00 59.95  ? 550  THR A O   1 
ATOM   3324 C  CB  . THR A 1 550 ? 177.680 178.745 132.211 1.00 59.95  ? 550  THR A CB  1 
ATOM   3325 O  OG1 . THR A 1 550 ? 177.303 180.026 131.694 1.00 59.95  ? 550  THR A OG1 1 
ATOM   3326 C  CG2 . THR A 1 550 ? 177.298 178.677 133.681 1.00 59.95  ? 550  THR A CG2 1 
ATOM   3327 N  N   . THR A 1 551 ? 179.839 176.408 131.012 1.00 54.03  ? 551  THR A N   1 
ATOM   3328 C  CA  . THR A 1 551 ? 179.882 174.950 131.005 1.00 54.03  ? 551  THR A CA  1 
ATOM   3329 C  C   . THR A 1 551 ? 181.143 174.409 131.669 1.00 54.03  ? 551  THR A C   1 
ATOM   3330 O  O   . THR A 1 551 ? 181.144 173.278 132.164 1.00 54.03  ? 551  THR A O   1 
ATOM   3331 C  CB  . THR A 1 551 ? 179.754 174.427 129.575 1.00 54.03  ? 551  THR A CB  1 
ATOM   3332 O  OG1 . THR A 1 551 ? 179.210 173.103 129.599 1.00 54.03  ? 551  THR A OG1 1 
ATOM   3333 C  CG2 . THR A 1 551 ? 181.100 174.400 128.889 1.00 54.03  ? 551  THR A CG2 1 
ATOM   3334 N  N   . ALA A 1 552 ? 182.229 175.180 131.683 1.00 51.11  ? 552  ALA A N   1 
ATOM   3335 C  CA  . ALA A 1 552 ? 183.455 174.680 132.304 1.00 51.11  ? 552  ALA A CA  1 
ATOM   3336 C  C   . ALA A 1 552 ? 183.322 174.516 133.813 1.00 51.11  ? 552  ALA A C   1 
ATOM   3337 O  O   . ALA A 1 552 ? 183.622 173.419 134.319 1.00 51.11  ? 552  ALA A O   1 
ATOM   3338 C  CB  . ALA A 1 552 ? 184.636 175.580 131.926 1.00 51.11  ? 552  ALA A CB  1 
ATOM   3339 N  N   . PRO A 1 553 ? 182.896 175.524 134.585 1.00 50.07  ? 553  PRO A N   1 
ATOM   3340 C  CA  . PRO A 1 553 ? 182.659 175.273 136.015 1.00 50.07  ? 553  PRO A CA  1 
ATOM   3341 C  C   . PRO A 1 553 ? 181.560 174.261 136.264 1.00 50.07  ? 553  PRO A C   1 
ATOM   3342 O  O   . PRO A 1 553 ? 181.624 173.527 137.254 1.00 50.07  ? 553  PRO A O   1 
ATOM   3343 C  CB  . PRO A 1 553 ? 182.287 176.659 136.564 1.00 50.07  ? 553  PRO A CB  1 
ATOM   3344 C  CG  . PRO A 1 553 ? 182.760 177.628 135.540 1.00 50.07  ? 553  PRO A CG  1 
ATOM   3345 C  CD  . PRO A 1 553 ? 182.594 176.924 134.238 1.00 50.07  ? 553  PRO A CD  1 
ATOM   3346 N  N   . ALA A 1 554 ? 180.550 174.197 135.393 1.00 48.58  ? 554  ALA A N   1 
ATOM   3347 C  CA  . ALA A 1 554 ? 179.483 173.219 135.574 1.00 48.58  ? 554  ALA A CA  1 
ATOM   3348 C  C   . ALA A 1 554 ? 180.009 171.797 135.442 1.00 48.58  ? 554  ALA A C   1 
ATOM   3349 O  O   . ALA A 1 554 ? 179.648 170.919 136.232 1.00 48.58  ? 554  ALA A O   1 
ATOM   3350 C  CB  . ALA A 1 554 ? 178.364 173.472 134.570 1.00 48.58  ? 554  ALA A CB  1 
ATOM   3351 N  N   . LEU A 1 555 ? 180.866 171.550 134.451 1.00 47.60  ? 555  LEU A N   1 
ATOM   3352 C  CA  . LEU A 1 555 ? 181.458 170.226 134.304 1.00 47.60  ? 555  LEU A CA  1 
ATOM   3353 C  C   . LEU A 1 555 ? 182.470 169.936 135.402 1.00 47.60  ? 555  LEU A C   1 
ATOM   3354 O  O   . LEU A 1 555 ? 182.632 168.778 135.799 1.00 47.60  ? 555  LEU A O   1 
ATOM   3355 C  CB  . LEU A 1 555 ? 182.109 170.087 132.932 1.00 47.60  ? 555  LEU A CB  1 
ATOM   3356 C  CG  . LEU A 1 555 ? 181.146 169.779 131.791 1.00 47.60  ? 555  LEU A CG  1 
ATOM   3357 C  CD1 . LEU A 1 555 ? 181.871 169.812 130.469 1.00 47.60  ? 555  LEU A CD1 1 
ATOM   3358 C  CD2 . LEU A 1 555 ? 180.521 168.423 132.012 1.00 47.60  ? 555  LEU A CD2 1 
ATOM   3359 N  N   . LYS A 1 556 ? 183.172 170.961 135.893 1.00 47.69  ? 556  LYS A N   1 
ATOM   3360 C  CA  . LYS A 1 556 ? 184.063 170.747 137.028 1.00 47.69  ? 556  LYS A CA  1 
ATOM   3361 C  C   . LYS A 1 556 ? 183.279 170.363 138.276 1.00 47.69  ? 556  LYS A C   1 
ATOM   3362 O  O   . LYS A 1 556 ? 183.716 169.510 139.057 1.00 47.69  ? 556  LYS A O   1 
ATOM   3363 C  CB  . LYS A 1 556 ? 184.901 171.997 137.285 1.00 47.69  ? 556  LYS A CB  1 
ATOM   3364 C  CG  . LYS A 1 556 ? 186.112 171.754 138.169 1.00 47.69  ? 556  LYS A CG  1 
ATOM   3365 C  CD  . LYS A 1 556 ? 187.307 172.575 137.710 1.00 47.69  ? 556  LYS A CD  1 
ATOM   3366 C  CE  . LYS A 1 556 ? 187.822 172.097 136.362 1.00 47.69  ? 556  LYS A CE  1 
ATOM   3367 N  NZ  . LYS A 1 556 ? 188.407 170.729 136.440 1.00 47.69  ? 556  LYS A NZ  1 
ATOM   3368 N  N   . ALA A 1 557 ? 182.118 170.985 138.482 1.00 44.80  ? 557  ALA A N   1 
ATOM   3369 C  CA  . ALA A 1 557 ? 181.299 170.704 139.654 1.00 44.80  ? 557  ALA A CA  1 
ATOM   3370 C  C   . ALA A 1 557 ? 180.541 169.391 139.534 1.00 44.80  ? 557  ALA A C   1 
ATOM   3371 O  O   . ALA A 1 557 ? 180.264 168.752 140.554 1.00 44.80  ? 557  ALA A O   1 
ATOM   3372 C  CB  . ALA A 1 557 ? 180.315 171.848 139.896 1.00 44.80  ? 557  ALA A CB  1 
ATOM   3373 N  N   . LEU A 1 558 ? 180.182 168.978 138.317 1.00 39.37  ? 558  LEU A N   1 
ATOM   3374 C  CA  . LEU A 1 558 ? 179.459 167.721 138.157 1.00 39.37  ? 558  LEU A CA  1 
ATOM   3375 C  C   . LEU A 1 558 ? 180.299 166.541 138.627 1.00 39.37  ? 558  LEU A C   1 
ATOM   3376 O  O   . LEU A 1 558 ? 179.768 165.578 139.190 1.00 39.37  ? 558  LEU A O   1 
ATOM   3377 C  CB  . LEU A 1 558 ? 179.030 167.530 136.704 1.00 39.37  ? 558  LEU A CB  1 
ATOM   3378 C  CG  . LEU A 1 558 ? 177.665 168.106 136.326 1.00 39.37  ? 558  LEU A CG  1 
ATOM   3379 C  CD1 . LEU A 1 558 ? 177.297 167.728 134.908 1.00 39.37  ? 558  LEU A CD1 1 
ATOM   3380 C  CD2 . LEU A 1 558 ? 176.603 167.636 137.291 1.00 39.37  ? 558  LEU A CD2 1 
ATOM   3381 N  N   . LYS A 1 559 ? 181.611 166.592 138.401 1.00 41.36  ? 559  LYS A N   1 
ATOM   3382 C  CA  . LYS A 1 559 ? 182.484 165.569 138.961 1.00 41.36  ? 559  LYS A CA  1 
ATOM   3383 C  C   . LYS A 1 559 ? 182.656 165.728 140.466 1.00 41.36  ? 559  LYS A C   1 
ATOM   3384 O  O   . LYS A 1 559 ? 182.935 164.742 141.155 1.00 41.36  ? 559  LYS A O   1 
ATOM   3385 C  CB  . LYS A 1 559 ? 183.844 165.596 138.266 1.00 41.36  ? 559  LYS A CB  1 
ATOM   3386 C  CG  . LYS A 1 559 ? 184.731 164.413 138.609 1.00 41.36  ? 559  LYS A CG  1 
ATOM   3387 C  CD  . LYS A 1 559 ? 185.994 164.401 137.772 1.00 41.36  ? 559  LYS A CD  1 
ATOM   3388 C  CE  . LYS A 1 559 ? 186.947 163.324 138.255 1.00 41.36  ? 559  LYS A CE  1 
ATOM   3389 N  NZ  . LYS A 1 559 ? 186.353 161.968 138.113 1.00 41.36  ? 559  LYS A NZ  1 
ATOM   3390 N  N   . ALA A 1 560 ? 182.489 166.942 140.994 1.00 40.27  ? 560  ALA A N   1 
ATOM   3391 C  CA  . ALA A 1 560 ? 182.531 167.142 142.436 1.00 40.27  ? 560  ALA A CA  1 
ATOM   3392 C  C   . ALA A 1 560 ? 181.300 166.587 143.140 1.00 40.27  ? 560  ALA A C   1 
ATOM   3393 O  O   . ALA A 1 560 ? 181.306 166.488 144.371 1.00 40.27  ? 560  ALA A O   1 
ATOM   3394 C  CB  . ALA A 1 560 ? 182.682 168.628 142.759 1.00 40.27  ? 560  ALA A CB  1 
ATOM   3395 N  N   . SER A 1 561 ? 180.250 166.242 142.399 1.00 39.19  ? 561  SER A N   1 
ATOM   3396 C  CA  . SER A 1 561 ? 179.067 165.603 142.954 1.00 39.19  ? 561  SER A CA  1 
ATOM   3397 C  C   . SER A 1 561 ? 179.053 164.101 142.714 1.00 39.19  ? 561  SER A C   1 
ATOM   3398 O  O   . SER A 1 561 ? 178.051 163.446 143.011 1.00 39.19  ? 561  SER A O   1 
ATOM   3399 C  CB  . SER A 1 561 ? 177.800 166.231 142.371 1.00 39.19  ? 561  SER A CB  1 
ATOM   3400 O  OG  . SER A 1 561 ? 177.676 167.586 142.761 1.00 39.19  ? 561  SER A OG  1 
ATOM   3401 N  N   . GLY A 1 562 ? 180.136 163.545 142.180 1.00 37.16  ? 562  GLY A N   1 
ATOM   3402 C  CA  . GLY A 1 562 ? 180.208 162.132 141.893 1.00 37.16  ? 562  GLY A CA  1 
ATOM   3403 C  C   . GLY A 1 562 ? 179.616 161.712 140.567 1.00 37.16  ? 562  GLY A C   1 
ATOM   3404 O  O   . GLY A 1 562 ? 179.653 160.519 140.245 1.00 37.16  ? 562  GLY A O   1 
ATOM   3405 N  N   . ILE A 1 563 ? 179.076 162.644 139.790 1.00 37.28  ? 563  ILE A N   1 
ATOM   3406 C  CA  . ILE A 1 563 ? 178.450 162.329 138.512 1.00 37.28  ? 563  ILE A CA  1 
ATOM   3407 C  C   . ILE A 1 563 ? 179.522 162.277 137.434 1.00 37.28  ? 563  ILE A C   1 
ATOM   3408 O  O   . ILE A 1 563 ? 180.288 163.231 137.258 1.00 37.28  ? 563  ILE A O   1 
ATOM   3409 C  CB  . ILE A 1 563 ? 177.368 163.361 138.160 1.00 37.28  ? 563  ILE A CB  1 
ATOM   3410 C  CG1 . ILE A 1 563 ? 176.088 163.072 138.936 1.00 37.28  ? 563  ILE A CG1 1 
ATOM   3411 C  CG2 . ILE A 1 563 ? 177.086 163.348 136.679 1.00 37.28  ? 563  ILE A CG2 1 
ATOM   3412 C  CD1 . ILE A 1 563 ? 175.183 164.261 139.064 1.00 37.28  ? 563  ILE A CD1 1 
ATOM   3413 N  N   . THR A 1 564 ? 179.579 161.162 136.714 1.00 40.05  ? 564  THR A N   1 
ATOM   3414 C  CA  . THR A 1 564 ? 180.510 160.997 135.606 1.00 40.05  ? 564  THR A CA  1 
ATOM   3415 C  C   . THR A 1 564 ? 179.818 161.417 134.318 1.00 40.05  ? 564  THR A C   1 
ATOM   3416 O  O   . THR A 1 564 ? 178.797 160.834 133.939 1.00 40.05  ? 564  THR A O   1 
ATOM   3417 C  CB  . THR A 1 564 ? 180.986 159.550 135.507 1.00 40.05  ? 564  THR A CB  1 
ATOM   3418 O  OG1 . THR A 1 564 ? 181.721 159.204 136.685 1.00 40.05  ? 564  THR A OG1 1 
ATOM   3419 C  CG2 . THR A 1 564 ? 181.873 159.371 134.293 1.00 40.05  ? 564  THR A CG2 1 
ATOM   3420 N  N   . VAL A 1 565 ? 180.369 162.422 133.647 1.00 40.84  ? 565  VAL A N   1 
ATOM   3421 C  CA  . VAL A 1 565 ? 179.752 162.955 132.438 1.00 40.84  ? 565  VAL A CA  1 
ATOM   3422 C  C   . VAL A 1 565 ? 180.272 162.192 131.230 1.00 40.84  ? 565  VAL A C   1 
ATOM   3423 O  O   . VAL A 1 565 ? 181.485 162.067 131.033 1.00 40.84  ? 565  VAL A O   1 
ATOM   3424 C  CB  . VAL A 1 565 ? 180.027 164.458 132.303 1.00 40.84  ? 565  VAL A CB  1 
ATOM   3425 C  CG1 . VAL A 1 565 ? 179.433 164.982 131.014 1.00 40.84  ? 565  VAL A CG1 1 
ATOM   3426 C  CG2 . VAL A 1 565 ? 179.458 165.200 133.486 1.00 40.84  ? 565  VAL A CG2 1 
ATOM   3427 N  N   . LYS A 1 566 ? 179.354 161.680 130.419 1.00 47.57  ? 566  LYS A N   1 
ATOM   3428 C  CA  . LYS A 1 566 ? 179.686 160.992 129.184 1.00 47.57  ? 566  LYS A CA  1 
ATOM   3429 C  C   . LYS A 1 566 ? 179.032 161.717 128.019 1.00 47.57  ? 566  LYS A C   1 
ATOM   3430 O  O   . LYS A 1 566 ? 177.942 162.278 128.154 1.00 47.57  ? 566  LYS A O   1 
ATOM   3431 C  CB  . LYS A 1 566 ? 179.224 159.534 129.213 1.00 47.57  ? 566  LYS A CB  1 
ATOM   3432 C  CG  . LYS A 1 566 ? 179.849 158.704 130.316 1.00 47.57  ? 566  LYS A CG  1 
ATOM   3433 C  CD  . LYS A 1 566 ? 179.757 157.224 130.006 1.00 47.57  ? 566  LYS A CD  1 
ATOM   3434 C  CE  . LYS A 1 566 ? 180.569 156.411 130.993 1.00 47.57  ? 566  LYS A CE  1 
ATOM   3435 N  NZ  . LYS A 1 566 ? 181.931 156.975 131.177 1.00 47.57  ? 566  LYS A NZ  1 
ATOM   3436 N  N   . ILE A 1 567 ? 179.703 161.704 126.873 1.00 49.63  ? 567  ILE A N   1 
ATOM   3437 C  CA  . ILE A 1 567 ? 179.234 162.399 125.681 1.00 49.63  ? 567  ILE A CA  1 
ATOM   3438 C  C   . ILE A 1 567 ? 178.877 161.356 124.634 1.00 49.63  ? 567  ILE A C   1 
ATOM   3439 O  O   . ILE A 1 567 ? 179.745 160.601 124.181 1.00 49.63  ? 567  ILE A O   1 
ATOM   3440 C  CB  . ILE A 1 567 ? 180.289 163.375 125.146 1.00 49.63  ? 567  ILE A CB  1 
ATOM   3441 C  CG1 . ILE A 1 567 ? 180.596 164.444 126.190 1.00 49.63  ? 567  ILE A CG1 1 
ATOM   3442 C  CG2 . ILE A 1 567 ? 179.806 164.024 123.874 1.00 49.63  ? 567  ILE A CG2 1 
ATOM   3443 C  CD1 . ILE A 1 567 ? 179.418 165.316 126.519 1.00 49.63  ? 567  ILE A CD1 1 
ATOM   3444 N  N   . LEU A 1 568 ? 177.607 161.311 124.250 1.00 53.41  ? 568  LEU A N   1 
ATOM   3445 C  CA  . LEU A 1 568 ? 177.136 160.438 123.179 1.00 53.41  ? 568  LEU A CA  1 
ATOM   3446 C  C   . LEU A 1 568 ? 176.740 161.341 122.019 1.00 53.41  ? 568  LEU A C   1 
ATOM   3447 O  O   . LEU A 1 568 ? 175.569 161.700 121.874 1.00 53.41  ? 568  LEU A O   1 
ATOM   3448 C  CB  . LEU A 1 568 ? 175.960 159.579 123.629 1.00 53.41  ? 568  LEU A CB  1 
ATOM   3449 C  CG  . LEU A 1 568 ? 175.940 158.989 125.038 1.00 53.41  ? 568  LEU A CG  1 
ATOM   3450 C  CD1 . LEU A 1 568 ? 174.784 158.014 125.172 1.00 53.41  ? 568  LEU A CD1 1 
ATOM   3451 C  CD2 . LEU A 1 568 ? 177.245 158.314 125.384 1.00 53.41  ? 568  LEU A CD2 1 
ATOM   3452 N  N   . THR A 1 569 ? 177.711 161.698 121.186 1.00 57.89  ? 569  THR A N   1 
ATOM   3453 C  CA  . THR A 1 569 ? 177.505 162.692 120.145 1.00 57.89  ? 569  THR A CA  1 
ATOM   3454 C  C   . THR A 1 569 ? 177.548 162.035 118.776 1.00 57.89  ? 569  THR A C   1 
ATOM   3455 O  O   . THR A 1 569 ? 178.344 161.123 118.538 1.00 57.89  ? 569  THR A O   1 
ATOM   3456 C  CB  . THR A 1 569 ? 178.555 163.802 120.223 1.00 57.89  ? 569  THR A CB  1 
ATOM   3457 O  OG1 . THR A 1 569 ? 178.423 164.668 119.090 1.00 57.89  ? 569  THR A OG1 1 
ATOM   3458 C  CG2 . THR A 1 569 ? 179.949 163.212 120.244 1.00 57.89  ? 569  THR A CG2 1 
ATOM   3459 N  N   . GLY A 1 570 ? 176.680 162.496 117.883 1.00 62.56  ? 570  GLY A N   1 
ATOM   3460 C  CA  . GLY A 1 570 ? 176.637 162.000 116.528 1.00 62.56  ? 570  GLY A CA  1 
ATOM   3461 C  C   . GLY A 1 570 ? 177.565 162.687 115.558 1.00 62.56  ? 570  GLY A C   1 
ATOM   3462 O  O   . GLY A 1 570 ? 177.584 162.331 114.376 1.00 62.56  ? 570  GLY A O   1 
ATOM   3463 N  N   . ASP A 1 571 ? 178.343 163.665 116.015 1.00 69.32  ? 571  ASP A N   1 
ATOM   3464 C  CA  . ASP A 1 571 ? 179.245 164.391 115.137 1.00 69.32  ? 571  ASP A CA  1 
ATOM   3465 C  C   . ASP A 1 571 ? 180.550 163.619 114.963 1.00 69.32  ? 571  ASP A C   1 
ATOM   3466 O  O   . ASP A 1 571 ? 180.706 162.488 115.431 1.00 69.32  ? 571  ASP A O   1 
ATOM   3467 C  CB  . ASP A 1 571 ? 179.505 165.792 115.682 1.00 69.32  ? 571  ASP A CB  1 
ATOM   3468 C  CG  . ASP A 1 571 ? 178.394 166.764 115.344 1.00 69.32  ? 571  ASP A CG  1 
ATOM   3469 O  OD1 . ASP A 1 571 ? 178.111 167.659 116.168 1.00 69.32  ? 571  ASP A OD1 1 
ATOM   3470 O  OD2 . ASP A 1 571 ? 177.803 166.635 114.251 1.00 69.32  ? 571  ASP A OD2 1 
ATOM   3471 N  N   . SER A 1 572 ? 181.502 164.241 114.274 1.00 76.22  ? 572  SER A N   1 
ATOM   3472 C  CA  . SER A 1 572 ? 182.785 163.602 114.023 1.00 76.22  ? 572  SER A CA  1 
ATOM   3473 C  C   . SER A 1 572 ? 183.578 163.464 115.315 1.00 76.22  ? 572  SER A C   1 
ATOM   3474 O  O   . SER A 1 572 ? 183.472 164.296 116.220 1.00 76.22  ? 572  SER A O   1 
ATOM   3475 C  CB  . SER A 1 572 ? 183.585 164.401 112.997 1.00 76.22  ? 572  SER A CB  1 
ATOM   3476 O  OG  . SER A 1 572 ? 184.648 163.627 112.469 1.00 76.22  ? 572  SER A OG  1 
ATOM   3477 N  N   . GLU A 1 573 ? 184.376 162.398 115.395 1.00 76.94  ? 573  GLU A N   1 
ATOM   3478 C  CA  . GLU A 1 573 ? 185.140 162.129 116.609 1.00 76.94  ? 573  GLU A CA  1 
ATOM   3479 C  C   . GLU A 1 573 ? 186.178 163.215 116.866 1.00 76.94  ? 573  GLU A C   1 
ATOM   3480 O  O   . GLU A 1 573 ? 186.435 163.576 118.021 1.00 76.94  ? 573  GLU A O   1 
ATOM   3481 C  CB  . GLU A 1 573 ? 185.799 160.750 116.522 1.00 76.94  ? 573  GLU A CB  1 
ATOM   3482 C  CG  . GLU A 1 573 ? 186.986 160.650 115.572 1.00 76.94  ? 573  GLU A CG  1 
ATOM   3483 C  CD  . GLU A 1 573 ? 186.598 160.802 114.111 1.00 76.94  ? 573  GLU A CD  1 
ATOM   3484 O  OE1 . GLU A 1 573 ? 185.392 160.722 113.799 1.00 76.94  ? 573  GLU A OE1 1 
ATOM   3485 O  OE2 . GLU A 1 573 ? 187.502 161.003 113.273 1.00 76.94  ? 573  GLU A OE2 1 
ATOM   3486 N  N   . LEU A 1 574 ? 186.785 163.749 115.805 1.00 81.43  ? 574  LEU A N   1 
ATOM   3487 C  CA  . LEU A 1 574 ? 187.772 164.809 115.977 1.00 81.43  ? 574  LEU A CA  1 
ATOM   3488 C  C   . LEU A 1 574 ? 187.141 166.054 116.582 1.00 81.43  ? 574  LEU A C   1 
ATOM   3489 O  O   . LEU A 1 574 ? 187.703 166.663 117.502 1.00 81.43  ? 574  LEU A O   1 
ATOM   3490 C  CB  . LEU A 1 574 ? 188.413 165.139 114.632 1.00 81.43  ? 574  LEU A CB  1 
ATOM   3491 C  CG  . LEU A 1 574 ? 188.939 163.943 113.842 1.00 81.43  ? 574  LEU A CG  1 
ATOM   3492 C  CD1 . LEU A 1 574 ? 188.949 164.262 112.360 1.00 81.43  ? 574  LEU A CD1 1 
ATOM   3493 C  CD2 . LEU A 1 574 ? 190.326 163.553 114.321 1.00 81.43  ? 574  LEU A CD2 1 
ATOM   3494 N  N   . VAL A 1 575 ? 185.967 166.444 116.081 1.00 78.30  ? 575  VAL A N   1 
ATOM   3495 C  CA  . VAL A 1 575 ? 185.314 167.659 116.560 1.00 78.30  ? 575  VAL A CA  1 
ATOM   3496 C  C   . VAL A 1 575 ? 184.926 167.511 118.024 1.00 78.30  ? 575  VAL A C   1 
ATOM   3497 O  O   . VAL A 1 575 ? 185.144 168.415 118.837 1.00 78.30  ? 575  VAL A O   1 
ATOM   3498 C  CB  . VAL A 1 575 ? 184.094 167.991 115.685 1.00 78.30  ? 575  VAL A CB  1 
ATOM   3499 C  CG1 . VAL A 1 575 ? 183.553 169.367 116.034 1.00 78.30  ? 575  VAL A CG1 1 
ATOM   3500 C  CG2 . VAL A 1 575 ? 184.462 167.910 114.215 1.00 78.30  ? 575  VAL A CG2 1 
ATOM   3501 N  N   . ALA A 1 576 ? 184.344 166.365 118.382 1.00 73.58  ? 576  ALA A N   1 
ATOM   3502 C  CA  . ALA A 1 576 ? 183.955 166.138 119.770 1.00 73.58  ? 576  ALA A CA  1 
ATOM   3503 C  C   . ALA A 1 576 ? 185.173 166.085 120.683 1.00 73.58  ? 576  ALA A C   1 
ATOM   3504 O  O   . ALA A 1 576 ? 185.146 166.620 121.799 1.00 73.58  ? 576  ALA A O   1 
ATOM   3505 C  CB  . ALA A 1 576 ? 183.141 164.852 119.882 1.00 73.58  ? 576  ALA A CB  1 
ATOM   3506 N  N   . ALA A 1 577 ? 186.249 165.437 120.230 1.00 75.45  ? 577  ALA A N   1 
ATOM   3507 C  CA  . ALA A 1 577 ? 187.458 165.363 121.041 1.00 75.45  ? 577  ALA A CA  1 
ATOM   3508 C  C   . ALA A 1 577 ? 188.042 166.747 121.281 1.00 75.45  ? 577  ALA A C   1 
ATOM   3509 O  O   . ALA A 1 577 ? 188.484 167.056 122.393 1.00 75.45  ? 577  ALA A O   1 
ATOM   3510 C  CB  . ALA A 1 577 ? 188.485 164.453 120.370 1.00 75.45  ? 577  ALA A CB  1 
ATOM   3511 N  N   . LYS A 1 578 ? 188.053 167.595 120.251 1.00 76.74  ? 578  LYS A N   1 
ATOM   3512 C  CA  . LYS A 1 578 ? 188.536 168.959 120.436 1.00 76.74  ? 578  LYS A CA  1 
ATOM   3513 C  C   . LYS A 1 578 ? 187.611 169.751 121.350 1.00 76.74  ? 578  LYS A C   1 
ATOM   3514 O  O   . LYS A 1 578 ? 188.076 170.545 122.175 1.00 76.74  ? 578  LYS A O   1 
ATOM   3515 C  CB  . LYS A 1 578 ? 188.685 169.657 119.086 1.00 76.74  ? 578  LYS A CB  1 
ATOM   3516 C  CG  . LYS A 1 578 ? 189.071 171.123 119.191 1.00 76.74  ? 578  LYS A CG  1 
ATOM   3517 C  CD  . LYS A 1 578 ? 190.340 171.306 120.006 1.00 76.74  ? 578  LYS A CD  1 
ATOM   3518 C  CE  . LYS A 1 578 ? 190.576 172.770 120.334 1.00 76.74  ? 578  LYS A CE  1 
ATOM   3519 N  NZ  . LYS A 1 578 ? 191.953 173.013 120.843 1.00 76.74  ? 578  LYS A NZ  1 
ATOM   3520 N  N   . VAL A 1 579 ? 186.298 169.547 121.219 1.00 71.95  ? 579  VAL A N   1 
ATOM   3521 C  CA  . VAL A 1 579 ? 185.341 170.251 122.068 1.00 71.95  ? 579  VAL A CA  1 
ATOM   3522 C  C   . VAL A 1 579 ? 185.571 169.905 123.531 1.00 71.95  ? 579  VAL A C   1 
ATOM   3523 O  O   . VAL A 1 579 ? 185.551 170.782 124.404 1.00 71.95  ? 579  VAL A O   1 
ATOM   3524 C  CB  . VAL A 1 579 ? 183.902 169.926 121.628 1.00 71.95  ? 579  VAL A CB  1 
ATOM   3525 C  CG1 . VAL A 1 579 ? 182.933 170.154 122.772 1.00 71.95  ? 579  VAL A CG1 1 
ATOM   3526 C  CG2 . VAL A 1 579 ? 183.516 170.777 120.432 1.00 71.95  ? 579  VAL A CG2 1 
ATOM   3527 N  N   . CYS A 1 580 ? 185.805 168.624 123.822 1.00 68.31  ? 580  CYS A N   1 
ATOM   3528 C  CA  . CYS A 1 580 ? 186.012 168.205 125.202 1.00 68.31  ? 580  CYS A CA  1 
ATOM   3529 C  C   . CYS A 1 580 ? 187.218 168.883 125.843 1.00 68.31  ? 580  CYS A C   1 
ATOM   3530 O  O   . CYS A 1 580 ? 187.289 168.958 127.073 1.00 68.31  ? 580  CYS A O   1 
ATOM   3531 C  CB  . CYS A 1 580 ? 186.170 166.687 125.271 1.00 68.31  ? 580  CYS A CB  1 
ATOM   3532 S  SG  . CYS A 1 580 ? 184.619 165.771 125.208 1.00 68.31  ? 580  CYS A SG  1 
ATOM   3533 N  N   . HIS A 1 581 ? 188.165 169.379 125.043 1.00 73.72  ? 581  HIS A N   1 
ATOM   3534 C  CA  . HIS A 1 581 ? 189.354 170.007 125.610 1.00 73.72  ? 581  HIS A CA  1 
ATOM   3535 C  C   . HIS A 1 581 ? 189.032 171.363 126.226 1.00 73.72  ? 581  HIS A C   1 
ATOM   3536 O  O   . HIS A 1 581 ? 189.485 171.674 127.333 1.00 73.72  ? 581  HIS A O   1 
ATOM   3537 C  CB  . HIS A 1 581 ? 190.436 170.147 124.542 1.00 73.72  ? 581  HIS A CB  1 
ATOM   3538 C  CG  . HIS A 1 581 ? 191.299 168.934 124.396 1.00 73.72  ? 581  HIS A CG  1 
ATOM   3539 N  ND1 . HIS A 1 581 ? 191.250 168.114 123.291 1.00 73.72  ? 581  HIS A ND1 1 
ATOM   3540 C  CD2 . HIS A 1 581 ? 192.234 168.403 125.219 1.00 73.72  ? 581  HIS A CD2 1 
ATOM   3541 C  CE1 . HIS A 1 581 ? 192.119 167.129 123.437 1.00 73.72  ? 581  HIS A CE1 1 
ATOM   3542 N  NE2 . HIS A 1 581 ? 192.729 167.282 124.599 1.00 73.72  ? 581  HIS A NE2 1 
ATOM   3543 N  N   . GLU A 1 582 ? 188.258 172.191 125.519 1.00 72.40  ? 582  GLU A N   1 
ATOM   3544 C  CA  . GLU A 1 582 ? 187.958 173.527 126.027 1.00 72.40  ? 582  GLU A CA  1 
ATOM   3545 C  C   . GLU A 1 582 ? 187.175 173.464 127.330 1.00 72.40  ? 582  GLU A C   1 
ATOM   3546 O  O   . GLU A 1 582 ? 187.455 174.215 128.270 1.00 72.40  ? 582  GLU A O   1 
ATOM   3547 C  CB  . GLU A 1 582 ? 187.182 174.329 124.983 1.00 72.40  ? 582  GLU A CB  1 
ATOM   3548 C  CG  . GLU A 1 582 ? 188.047 175.165 124.058 1.00 72.40  ? 582  GLU A CG  1 
ATOM   3549 C  CD  . GLU A 1 582 ? 188.500 174.400 122.834 1.00 72.40  ? 582  GLU A CD  1 
ATOM   3550 O  OE1 . GLU A 1 582 ? 188.638 173.163 122.921 1.00 72.40  ? 582  GLU A OE1 1 
ATOM   3551 O  OE2 . GLU A 1 582 ? 188.715 175.037 121.782 1.00 72.40  ? 582  GLU A OE2 1 
ATOM   3552 N  N   . VAL A 1 583 ? 186.187 172.571 127.404 1.00 66.10  ? 583  VAL A N   1 
ATOM   3553 C  CA  . VAL A 1 583 ? 185.349 172.493 128.593 1.00 66.10  ? 583  VAL A CA  1 
ATOM   3554 C  C   . VAL A 1 583 ? 186.139 171.961 129.781 1.00 66.10  ? 583  VAL A C   1 
ATOM   3555 O  O   . VAL A 1 583 ? 185.829 172.282 130.935 1.00 66.10  ? 583  VAL A O   1 
ATOM   3556 C  CB  . VAL A 1 583 ? 184.106 171.633 128.304 1.00 66.10  ? 583  VAL A CB  1 
ATOM   3557 C  CG1 . VAL A 1 583 ? 183.307 172.239 127.169 1.00 66.10  ? 583  VAL A CG1 1 
ATOM   3558 C  CG2 . VAL A 1 583 ? 184.504 170.210 127.970 1.00 66.10  ? 583  VAL A CG2 1 
ATOM   3559 N  N   . GLY A 1 584 ? 187.166 171.152 129.532 1.00 63.76  ? 584  GLY A N   1 
ATOM   3560 C  CA  . GLY A 1 584 ? 187.935 170.527 130.589 1.00 63.76  ? 584  GLY A CA  1 
ATOM   3561 C  C   . GLY A 1 584 ? 187.679 169.049 130.766 1.00 63.76  ? 584  GLY A C   1 
ATOM   3562 O  O   . GLY A 1 584 ? 188.380 168.409 131.557 1.00 63.76  ? 584  GLY A O   1 
ATOM   3563 N  N   . LEU A 1 585 ? 186.698 168.485 130.068 1.00 63.62  ? 585  LEU A N   1 
ATOM   3564 C  CA  . LEU A 1 585 ? 186.459 167.052 130.133 1.00 63.62  ? 585  LEU A CA  1 
ATOM   3565 C  C   . LEU A 1 585 ? 187.631 166.304 129.511 1.00 63.62  ? 585  LEU A C   1 
ATOM   3566 O  O   . LEU A 1 585 ? 188.179 166.719 128.487 1.00 63.62  ? 585  LEU A O   1 
ATOM   3567 C  CB  . LEU A 1 585 ? 185.159 166.705 129.407 1.00 63.62  ? 585  LEU A CB  1 
ATOM   3568 C  CG  . LEU A 1 585 ? 184.434 165.399 129.736 1.00 63.62  ? 585  LEU A CG  1 
ATOM   3569 C  CD1 . LEU A 1 585 ? 182.941 165.592 129.568 1.00 63.62  ? 585  LEU A CD1 1 
ATOM   3570 C  CD2 . LEU A 1 585 ? 184.916 164.258 128.861 1.00 63.62  ? 585  LEU A CD2 1 
ATOM   3571 N  N   . ASP A 1 586 ? 188.023 165.199 130.137 1.00 70.63  ? 586  ASP A N   1 
ATOM   3572 C  CA  . ASP A 1 586 ? 189.170 164.424 129.670 1.00 70.63  ? 586  ASP A CA  1 
ATOM   3573 C  C   . ASP A 1 586 ? 188.686 163.406 128.648 1.00 70.63  ? 586  ASP A C   1 
ATOM   3574 O  O   . ASP A 1 586 ? 188.126 162.368 129.004 1.00 70.63  ? 586  ASP A O   1 
ATOM   3575 C  CB  . ASP A 1 586 ? 189.872 163.743 130.837 1.00 70.63  ? 586  ASP A CB  1 
ATOM   3576 C  CG  . ASP A 1 586 ? 191.336 163.476 130.556 1.00 70.63  ? 586  ASP A CG  1 
ATOM   3577 O  OD1 . ASP A 1 586 ? 192.110 164.452 130.456 1.00 70.63  ? 586  ASP A OD1 1 
ATOM   3578 O  OD2 . ASP A 1 586 ? 191.713 162.293 130.430 1.00 70.63  ? 586  ASP A OD2 1 
ATOM   3579 N  N   . ALA A 1 587 ? 188.908 163.704 127.366 1.00 69.86  ? 587  ALA A N   1 
ATOM   3580 C  CA  . ALA A 1 587 ? 188.468 162.800 126.309 1.00 69.86  ? 587  ALA A CA  1 
ATOM   3581 C  C   . ALA A 1 587 ? 189.207 161.470 126.373 1.00 69.86  ? 587  ALA A C   1 
ATOM   3582 O  O   . ALA A 1 587 ? 188.604 160.408 126.183 1.00 69.86  ? 587  ALA A O   1 
ATOM   3583 C  CB  . ALA A 1 587 ? 188.662 163.456 124.944 1.00 69.86  ? 587  ALA A CB  1 
ATOM   3584 N  N   . GLY A 1 588 ? 190.506 161.508 126.639 1.00 71.21  ? 588  GLY A N   1 
ATOM   3585 C  CA  . GLY A 1 588 ? 191.285 160.281 126.682 1.00 71.21  ? 588  GLY A CA  1 
ATOM   3586 C  C   . GLY A 1 588 ? 191.294 159.612 125.323 1.00 71.21  ? 588  GLY A C   1 
ATOM   3587 O  O   . GLY A 1 588 ? 191.696 160.206 124.315 1.00 71.21  ? 588  GLY A O   1 
ATOM   3588 N  N   . GLU A 1 589 ? 190.849 158.360 125.281 1.00 72.13  ? 589  GLU A N   1 
ATOM   3589 C  CA  . GLU A 1 589 ? 190.713 157.619 124.036 1.00 72.13  ? 589  GLU A CA  1 
ATOM   3590 C  C   . GLU A 1 589 ? 189.262 157.678 123.579 1.00 72.13  ? 589  GLU A C   1 
ATOM   3591 O  O   . GLU A 1 589 ? 188.342 157.634 124.403 1.00 72.13  ? 589  GLU A O   1 
ATOM   3592 C  CB  . GLU A 1 589 ? 191.182 156.170 124.200 1.00 72.13  ? 589  GLU A CB  1 
ATOM   3593 C  CG  . GLU A 1 589 ? 190.104 155.169 124.586 1.00 72.13  ? 589  GLU A CG  1 
ATOM   3594 C  CD  . GLU A 1 589 ? 190.194 154.747 126.041 1.00 72.13  ? 589  GLU A CD  1 
ATOM   3595 O  OE1 . GLU A 1 589 ? 190.883 155.437 126.820 1.00 72.13  ? 589  GLU A OE1 1 
ATOM   3596 O  OE2 . GLU A 1 589 ? 189.576 153.724 126.403 1.00 72.13  ? 589  GLU A OE2 1 
ATOM   3597 N  N   . VAL A 1 590 ? 189.064 157.819 122.272 1.00 66.72  ? 590  VAL A N   1 
ATOM   3598 C  CA  . VAL A 1 590 ? 187.721 157.964 121.731 1.00 66.72  ? 590  VAL A CA  1 
ATOM   3599 C  C   . VAL A 1 590 ? 187.191 156.607 121.281 1.00 66.72  ? 590  VAL A C   1 
ATOM   3600 O  O   . VAL A 1 590 ? 187.941 155.653 121.063 1.00 66.72  ? 590  VAL A O   1 
ATOM   3601 C  CB  . VAL A 1 590 ? 187.702 158.982 120.579 1.00 66.72  ? 590  VAL A CB  1 
ATOM   3602 C  CG1 . VAL A 1 590 ? 188.463 160.234 120.974 1.00 66.72  ? 590  VAL A CG1 1 
ATOM   3603 C  CG2 . VAL A 1 590 ? 188.295 158.371 119.323 1.00 66.72  ? 590  VAL A CG2 1 
ATOM   3604 N  N   . VAL A 1 591 ? 185.870 156.524 121.148 1.00 63.87  ? 591  VAL A N   1 
ATOM   3605 C  CA  . VAL A 1 591 ? 185.199 155.322 120.669 1.00 63.87  ? 591  VAL A CA  1 
ATOM   3606 C  C   . VAL A 1 591 ? 184.302 155.724 119.510 1.00 63.87  ? 591  VAL A C   1 
ATOM   3607 O  O   . VAL A 1 591 ? 183.467 156.625 119.649 1.00 63.87  ? 591  VAL A O   1 
ATOM   3608 C  CB  . VAL A 1 591 ? 184.382 154.634 121.775 1.00 63.87  ? 591  VAL A CB  1 
ATOM   3609 C  CG1 . VAL A 1 591 ? 183.214 153.870 121.178 1.00 63.87  ? 591  VAL A CG1 1 
ATOM   3610 C  CG2 . VAL A 1 591 ? 185.266 153.708 122.588 1.00 63.87  ? 591  VAL A CG2 1 
ATOM   3611 N  N   . ILE A 1 592 ? 184.480 155.068 118.368 1.00 71.48  ? 592  ILE A N   1 
ATOM   3612 C  CA  . ILE A 1 592 ? 183.664 155.364 117.201 1.00 71.48  ? 592  ILE A CA  1 
ATOM   3613 C  C   . ILE A 1 592 ? 182.463 154.425 117.164 1.00 71.48  ? 592  ILE A C   1 
ATOM   3614 O  O   . ILE A 1 592 ? 182.536 153.259 117.557 1.00 71.48  ? 592  ILE A O   1 
ATOM   3615 C  CB  . ILE A 1 592 ? 184.500 155.262 115.913 1.00 71.48  ? 592  ILE A CB  1 
ATOM   3616 C  CG1 . ILE A 1 592 ? 185.807 156.040 116.070 1.00 71.48  ? 592  ILE A CG1 1 
ATOM   3617 C  CG2 . ILE A 1 592 ? 183.721 155.796 114.722 1.00 71.48  ? 592  ILE A CG2 1 
ATOM   3618 C  CD1 . ILE A 1 592 ? 186.675 156.036 114.832 1.00 71.48  ? 592  ILE A CD1 1 
ATOM   3619 N  N   . GLY A 1 593 ? 181.335 154.948 116.679 1.00 76.77  ? 593  GLY A N   1 
ATOM   3620 C  CA  . GLY A 1 593 ? 180.115 154.162 116.628 1.00 76.77  ? 593  GLY A CA  1 
ATOM   3621 C  C   . GLY A 1 593 ? 180.193 152.957 115.717 1.00 76.77  ? 593  GLY A C   1 
ATOM   3622 O  O   . GLY A 1 593 ? 179.360 152.053 115.831 1.00 76.77  ? 593  GLY A O   1 
ATOM   3623 N  N   . SER A 1 594 ? 181.167 152.927 114.805 1.00 82.63  ? 594  SER A N   1 
ATOM   3624 C  CA  . SER A 1 594 ? 181.359 151.744 113.975 1.00 82.63  ? 594  SER A CA  1 
ATOM   3625 C  C   . SER A 1 594 ? 181.869 150.568 114.799 1.00 82.63  ? 594  SER A C   1 
ATOM   3626 O  O   . SER A 1 594 ? 181.441 149.427 114.594 1.00 82.63  ? 594  SER A O   1 
ATOM   3627 C  CB  . SER A 1 594 ? 182.324 152.055 112.832 1.00 82.63  ? 594  SER A CB  1 
ATOM   3628 O  OG  . SER A 1 594 ? 182.564 150.904 112.043 1.00 82.63  ? 594  SER A OG  1 
ATOM   3629 N  N   . ASP A 1 595 ? 182.785 150.829 115.734 1.00 86.24  ? 595  ASP A N   1 
ATOM   3630 C  CA  . ASP A 1 595 ? 183.367 149.753 116.529 1.00 86.24  ? 595  ASP A CA  1 
ATOM   3631 C  C   . ASP A 1 595 ? 182.325 149.085 117.418 1.00 86.24  ? 595  ASP A C   1 
ATOM   3632 O  O   . ASP A 1 595 ? 182.317 147.856 117.556 1.00 86.24  ? 595  ASP A O   1 
ATOM   3633 C  CB  . ASP A 1 595 ? 184.528 150.295 117.366 1.00 86.24  ? 595  ASP A CB  1 
ATOM   3634 C  CG  . ASP A 1 595 ? 184.967 149.333 118.456 1.00 86.24  ? 595  ASP A CG  1 
ATOM   3635 O  OD1 . ASP A 1 595 ? 185.993 148.648 118.264 1.00 86.24  ? 595  ASP A OD1 1 
ATOM   3636 O  OD2 . ASP A 1 595 ? 184.307 149.279 119.515 1.00 86.24  ? 595  ASP A OD2 1 
ATOM   3637 N  N   . ILE A 1 596 ? 181.438 149.874 118.031 1.00 85.85  ? 596  ILE A N   1 
ATOM   3638 C  CA  . ILE A 1 596 ? 180.474 149.321 118.974 1.00 85.85  ? 596  ILE A CA  1 
ATOM   3639 C  C   . ILE A 1 596 ? 179.483 148.383 118.301 1.00 85.85  ? 596  ILE A C   1 
ATOM   3640 O  O   . ILE A 1 596 ? 178.860 147.559 118.979 1.00 85.85  ? 596  ILE A O   1 
ATOM   3641 C  CB  . ILE A 1 596 ? 179.724 150.447 119.707 1.00 85.85  ? 596  ILE A CB  1 
ATOM   3642 C  CG1 . ILE A 1 596 ? 178.737 151.134 118.766 1.00 85.85  ? 596  ILE A CG1 1 
ATOM   3643 C  CG2 . ILE A 1 596 ? 180.704 151.452 120.286 1.00 85.85  ? 596  ILE A CG2 1 
ATOM   3644 C  CD1 . ILE A 1 596 ? 177.798 152.075 119.464 1.00 85.85  ? 596  ILE A CD1 1 
ATOM   3645 N  N   . GLU A 1 597 ? 179.312 148.492 116.982 1.00 86.62  ? 597  GLU A N   1 
ATOM   3646 C  CA  . GLU A 1 597 ? 178.390 147.603 116.285 1.00 86.62  ? 597  GLU A CA  1 
ATOM   3647 C  C   . GLU A 1 597 ? 178.852 146.154 116.374 1.00 86.62  ? 597  GLU A C   1 
ATOM   3648 O  O   . GLU A 1 597 ? 178.033 145.240 116.529 1.00 86.62  ? 597  GLU A O   1 
ATOM   3649 C  CB  . GLU A 1 597 ? 178.252 148.036 114.826 1.00 86.62  ? 597  GLU A CB  1 
ATOM   3650 C  CG  . GLU A 1 597 ? 177.197 147.272 114.051 1.00 86.62  ? 597  GLU A CG  1 
ATOM   3651 C  CD  . GLU A 1 597 ? 175.790 147.647 114.468 1.00 86.62  ? 597  GLU A CD  1 
ATOM   3652 O  OE1 . GLU A 1 597 ? 175.596 148.780 114.955 1.00 86.62  ? 597  GLU A OE1 1 
ATOM   3653 O  OE2 . GLU A 1 597 ? 174.878 146.809 114.309 1.00 86.62  ? 597  GLU A OE2 1 
ATOM   3654 N  N   . THR A 1 598 ? 180.164 145.926 116.282 1.00 90.69  ? 598  THR A N   1 
ATOM   3655 C  CA  . THR A 1 598 ? 180.686 144.564 116.277 1.00 90.69  ? 598  THR A CA  1 
ATOM   3656 C  C   . THR A 1 598 ? 180.601 143.922 117.657 1.00 90.69  ? 598  THR A C   1 
ATOM   3657 O  O   . THR A 1 598 ? 180.420 142.704 117.769 1.00 90.69  ? 598  THR A O   1 
ATOM   3658 C  CB  . THR A 1 598 ? 182.130 144.560 115.776 1.00 90.69  ? 598  THR A CB  1 
ATOM   3659 O  OG1 . THR A 1 598 ? 183.004 144.976 116.832 1.00 90.69  ? 598  THR A OG1 1 
ATOM   3660 C  CG2 . THR A 1 598 ? 182.286 145.510 114.598 1.00 90.69  ? 598  THR A CG2 1 
ATOM   3661 N  N   . LEU A 1 599 ? 180.734 144.716 118.716 1.00 87.52  ? 599  LEU A N   1 
ATOM   3662 C  CA  . LEU A 1 599 ? 180.767 144.167 120.063 1.00 87.52  ? 599  LEU A CA  1 
ATOM   3663 C  C   . LEU A 1 599 ? 179.391 143.659 120.487 1.00 87.52  ? 599  LEU A C   1 
ATOM   3664 O  O   . LEU A 1 599 ? 178.353 144.057 119.951 1.00 87.52  ? 599  LEU A O   1 
ATOM   3665 C  CB  . LEU A 1 599 ? 181.261 145.212 121.065 1.00 87.52  ? 599  LEU A CB  1 
ATOM   3666 C  CG  . LEU A 1 599 ? 182.767 145.380 121.298 1.00 87.52  ? 599  LEU A CG  1 
ATOM   3667 C  CD1 . LEU A 1 599 ? 183.580 145.231 120.019 1.00 87.52  ? 599  LEU A CD1 1 
ATOM   3668 C  CD2 . LEU A 1 599 ? 183.055 146.717 121.964 1.00 87.52  ? 599  LEU A CD2 1 
ATOM   3669 N  N   . SER A 1 600 ? 179.399 142.757 121.466 1.00 88.98  ? 600  SER A N   1 
ATOM   3670 C  CA  . SER A 1 600 ? 178.181 142.248 122.072 1.00 88.98  ? 600  SER A CA  1 
ATOM   3671 C  C   . SER A 1 600 ? 177.807 143.110 123.277 1.00 88.98  ? 600  SER A C   1 
ATOM   3672 O  O   . SER A 1 600 ? 178.394 144.164 123.524 1.00 88.98  ? 600  SER A O   1 
ATOM   3673 C  CB  . SER A 1 600 ? 178.350 140.783 122.471 1.00 88.98  ? 600  SER A CB  1 
ATOM   3674 O  OG  . SER A 1 600 ? 179.198 140.658 123.599 1.00 88.98  ? 600  SER A OG  1 
ATOM   3675 N  N   . ASP A 1 601 ? 176.815 142.653 124.043 1.00 86.54  ? 601  ASP A N   1 
ATOM   3676 C  CA  . ASP A 1 601 ? 176.300 143.460 125.146 1.00 86.54  ? 601  ASP A CA  1 
ATOM   3677 C  C   . ASP A 1 601 ? 177.334 143.628 126.254 1.00 86.54  ? 601  ASP A C   1 
ATOM   3678 O  O   . ASP A 1 601 ? 177.619 144.752 126.685 1.00 86.54  ? 601  ASP A O   1 
ATOM   3679 C  CB  . ASP A 1 601 ? 175.021 142.830 125.699 1.00 86.54  ? 601  ASP A CB  1 
ATOM   3680 C  CG  . ASP A 1 601 ? 173.854 142.943 124.740 1.00 86.54  ? 601  ASP A CG  1 
ATOM   3681 O  OD1 . ASP A 1 601 ? 174.010 143.589 123.683 1.00 86.54  ? 601  ASP A OD1 1 
ATOM   3682 O  OD2 . ASP A 1 601 ? 172.778 142.386 125.045 1.00 86.54  ? 601  ASP A OD2 1 
ATOM   3683 N  N   . ASP A 1 602 ? 177.915 142.522 126.720 1.00 86.56  ? 602  ASP A N   1 
ATOM   3684 C  CA  . ASP A 1 602 ? 178.756 142.578 127.913 1.00 86.56  ? 602  ASP A CA  1 
ATOM   3685 C  C   . ASP A 1 602 ? 180.072 143.295 127.640 1.00 86.56  ? 602  ASP A C   1 
ATOM   3686 O  O   . ASP A 1 602 ? 180.506 144.136 128.439 1.00 86.56  ? 602  ASP A O   1 
ATOM   3687 C  CB  . ASP A 1 602 ? 179.009 141.165 128.437 1.00 86.56  ? 602  ASP A CB  1 
ATOM   3688 C  CG  . ASP A 1 602 ? 177.802 140.584 129.149 1.00 86.56  ? 602  ASP A CG  1 
ATOM   3689 O  OD1 . ASP A 1 602 ? 176.713 141.188 129.064 1.00 86.56  ? 602  ASP A OD1 1 
ATOM   3690 O  OD2 . ASP A 1 602 ? 177.941 139.524 129.793 1.00 86.56  ? 602  ASP A OD2 1 
ATOM   3691 N  N   . GLU A 1 603 ? 180.723 142.976 126.520 1.00 86.54  ? 603  GLU A N   1 
ATOM   3692 C  CA  . GLU A 1 603 ? 181.981 143.636 126.188 1.00 86.54  ? 603  GLU A CA  1 
ATOM   3693 C  C   . GLU A 1 603 ? 181.771 145.123 125.933 1.00 86.54  ? 603  GLU A C   1 
ATOM   3694 O  O   . GLU A 1 603 ? 182.602 145.951 126.326 1.00 86.54  ? 603  GLU A O   1 
ATOM   3695 C  CB  . GLU A 1 603 ? 182.623 142.956 124.980 1.00 86.54  ? 603  GLU A CB  1 
ATOM   3696 C  CG  . GLU A 1 603 ? 181.682 142.756 123.809 1.00 86.54  ? 603  GLU A CG  1 
ATOM   3697 C  CD  . GLU A 1 603 ? 182.077 141.581 122.940 1.00 86.54  ? 603  GLU A CD  1 
ATOM   3698 O  OE1 . GLU A 1 603 ? 182.149 141.748 121.705 1.00 86.54  ? 603  GLU A OE1 1 
ATOM   3699 O  OE2 . GLU A 1 603 ? 182.311 140.486 123.493 1.00 86.54  ? 603  GLU A OE2 1 
ATOM   3700 N  N   . LEU A 1 604 ? 180.664 145.485 125.280 1.00 83.55  ? 604  LEU A N   1 
ATOM   3701 C  CA  . LEU A 1 604 ? 180.366 146.899 125.078 1.00 83.55  ? 604  LEU A CA  1 
ATOM   3702 C  C   . LEU A 1 604 ? 180.100 147.612 126.395 1.00 83.55  ? 604  LEU A C   1 
ATOM   3703 O  O   . LEU A 1 604 ? 180.510 148.764 126.561 1.00 83.55  ? 604  LEU A O   1 
ATOM   3704 C  CB  . LEU A 1 604 ? 179.177 147.070 124.137 1.00 83.55  ? 604  LEU A CB  1 
ATOM   3705 C  CG  . LEU A 1 604 ? 179.005 148.487 123.597 1.00 83.55  ? 604  LEU A CG  1 
ATOM   3706 C  CD1 . LEU A 1 604 ? 180.274 148.921 122.900 1.00 83.55  ? 604  LEU A CD1 1 
ATOM   3707 C  CD2 . LEU A 1 604 ? 177.824 148.561 122.649 1.00 83.55  ? 604  LEU A CD2 1 
ATOM   3708 N  N   . ALA A 1 605 ? 179.407 146.961 127.331 1.00 80.93  ? 605  ALA A N   1 
ATOM   3709 C  CA  . ALA A 1 605 ? 179.204 147.566 128.643 1.00 80.93  ? 605  ALA A CA  1 
ATOM   3710 C  C   . ALA A 1 605 ? 180.535 147.777 129.353 1.00 80.93  ? 605  ALA A C   1 
ATOM   3711 O  O   . ALA A 1 605 ? 180.769 148.825 129.968 1.00 80.93  ? 605  ALA A O   1 
ATOM   3712 C  CB  . ALA A 1 605 ? 178.271 146.696 129.485 1.00 80.93  ? 605  ALA A CB  1 
ATOM   3713 N  N   . ASN A 1 606 ? 181.424 146.785 129.268 1.00 81.13  ? 606  ASN A N   1 
ATOM   3714 C  CA  . ASN A 1 606 ? 182.744 146.918 129.876 1.00 81.13  ? 606  ASN A CA  1 
ATOM   3715 C  C   . ASN A 1 606 ? 183.515 148.078 129.256 1.00 81.13  ? 606  ASN A C   1 
ATOM   3716 O  O   . ASN A 1 606 ? 184.170 148.850 129.967 1.00 81.13  ? 606  ASN A O   1 
ATOM   3717 C  CB  . ASN A 1 606 ? 183.516 145.605 129.726 1.00 81.13  ? 606  ASN A CB  1 
ATOM   3718 C  CG  . ASN A 1 606 ? 185.022 145.797 129.743 1.00 81.13  ? 606  ASN A CG  1 
ATOM   3719 O  OD1 . ASN A 1 606 ? 185.563 146.526 130.576 1.00 81.13  ? 606  ASN A OD1 1 
ATOM   3720 N  ND2 . ASN A 1 606 ? 185.709 145.143 128.813 1.00 81.13  ? 606  ASN A ND2 1 
ATOM   3721 N  N   . LEU A 1 607 ? 183.449 148.216 127.929 1.00 78.09  ? 607  LEU A N   1 
ATOM   3722 C  CA  . LEU A 1 607 ? 184.121 149.329 127.263 1.00 78.09  ? 607  LEU A CA  1 
ATOM   3723 C  C   . LEU A 1 607 ? 183.523 150.668 127.679 1.00 78.09  ? 607  LEU A C   1 
ATOM   3724 O  O   . LEU A 1 607 ? 184.255 151.627 127.949 1.00 78.09  ? 607  LEU A O   1 
ATOM   3725 C  CB  . LEU A 1 607 ? 184.038 149.158 125.747 1.00 78.09  ? 607  LEU A CB  1 
ATOM   3726 C  CG  . LEU A 1 607 ? 184.946 150.060 124.909 1.00 78.09  ? 607  LEU A CG  1 
ATOM   3727 C  CD1 . LEU A 1 607 ? 186.397 149.630 125.030 1.00 78.09  ? 607  LEU A CD1 1 
ATOM   3728 C  CD2 . LEU A 1 607 ? 184.505 150.061 123.456 1.00 78.09  ? 607  LEU A CD2 1 
ATOM   3729 N  N   . ALA A 1 608 ? 182.192 150.749 127.740 1.00 73.87  ? 608  ALA A N   1 
ATOM   3730 C  CA  . ALA A 1 608 ? 181.523 151.995 128.089 1.00 73.87  ? 608  ALA A CA  1 
ATOM   3731 C  C   . ALA A 1 608 ? 181.749 152.387 129.539 1.00 73.87  ? 608  ALA A C   1 
ATOM   3732 O  O   . ALA A 1 608 ? 181.630 153.570 129.874 1.00 73.87  ? 608  ALA A O   1 
ATOM   3733 C  CB  . ALA A 1 608 ? 180.025 151.882 127.810 1.00 73.87  ? 608  ALA A CB  1 
ATOM   3734 N  N   . GLN A 1 609 ? 182.060 151.423 130.406 1.00 73.29  ? 609  GLN A N   1 
ATOM   3735 C  CA  . GLN A 1 609 ? 182.345 151.759 131.796 1.00 73.29  ? 609  GLN A CA  1 
ATOM   3736 C  C   . GLN A 1 609 ? 183.583 152.642 131.915 1.00 73.29  ? 609  GLN A C   1 
ATOM   3737 O  O   . GLN A 1 609 ? 183.623 153.554 132.749 1.00 73.29  ? 609  GLN A O   1 
ATOM   3738 C  CB  . GLN A 1 609 ? 182.518 150.483 132.619 1.00 73.29  ? 609  GLN A CB  1 
ATOM   3739 C  CG  . GLN A 1 609 ? 181.213 149.806 133.002 1.00 73.29  ? 609  GLN A CG  1 
ATOM   3740 C  CD  . GLN A 1 609 ? 180.319 150.694 133.842 1.00 73.29  ? 609  GLN A CD  1 
ATOM   3741 O  OE1 . GLN A 1 609 ? 179.258 151.126 133.395 1.00 73.29  ? 609  GLN A OE1 1 
ATOM   3742 N  NE2 . GLN A 1 609 ? 180.745 150.972 135.068 1.00 73.29  ? 609  GLN A NE2 1 
ATOM   3743 N  N   . ARG A 1 610 ? 184.602 152.392 131.092 1.00 75.07  ? 610  ARG A N   1 
ATOM   3744 C  CA  . ARG A 1 610 ? 185.886 153.070 131.222 1.00 75.07  ? 610  ARG A CA  1 
ATOM   3745 C  C   . ARG A 1 610 ? 186.155 154.080 130.112 1.00 75.07  ? 610  ARG A C   1 
ATOM   3746 O  O   . ARG A 1 610 ? 187.290 154.551 129.981 1.00 75.07  ? 610  ARG A O   1 
ATOM   3747 C  CB  . ARG A 1 610 ? 187.020 152.043 131.274 1.00 75.07  ? 610  ARG A CB  1 
ATOM   3748 C  CG  . ARG A 1 610 ? 187.279 151.327 129.961 1.00 75.07  ? 610  ARG A CG  1 
ATOM   3749 C  CD  . ARG A 1 610 ? 188.355 150.268 130.127 1.00 75.07  ? 610  ARG A CD  1 
ATOM   3750 N  NE  . ARG A 1 610 ? 188.692 149.626 128.863 1.00 75.07  ? 610  ARG A NE  1 
ATOM   3751 C  CZ  . ARG A 1 610 ? 188.010 148.622 128.329 1.00 75.07  ? 610  ARG A CZ  1 
ATOM   3752 N  NH1 . ARG A 1 610 ? 186.932 148.129 128.916 1.00 75.07  ? 610  ARG A NH1 1 
ATOM   3753 N  NH2 . ARG A 1 610 ? 188.419 148.100 127.177 1.00 75.07  ? 610  ARG A NH2 1 
ATOM   3754 N  N   . THR A 1 611 ? 185.150 154.432 129.317 1.00 69.16  ? 611  THR A N   1 
ATOM   3755 C  CA  . THR A 1 611 ? 185.305 155.416 128.255 1.00 69.16  ? 611  THR A CA  1 
ATOM   3756 C  C   . THR A 1 611 ? 184.343 156.571 128.490 1.00 69.16  ? 611  THR A C   1 
ATOM   3757 O  O   . THR A 1 611 ? 183.297 156.408 129.123 1.00 69.16  ? 611  THR A O   1 
ATOM   3758 C  CB  . THR A 1 611 ? 185.063 154.799 126.873 1.00 69.16  ? 611  THR A CB  1 
ATOM   3759 O  OG1 . THR A 1 611 ? 183.831 154.068 126.886 1.00 69.16  ? 611  THR A OG1 1 
ATOM   3760 C  CG2 . THR A 1 611 ? 186.199 153.864 126.502 1.00 69.16  ? 611  THR A CG2 1 
ATOM   3761 N  N   . THR A 1 612 ? 184.706 157.745 127.976 1.00 61.38  ? 612  THR A N   1 
ATOM   3762 C  CA  . THR A 1 612 ? 183.955 158.960 128.265 1.00 61.38  ? 612  THR A CA  1 
ATOM   3763 C  C   . THR A 1 612 ? 183.207 159.523 127.063 1.00 61.38  ? 612  THR A C   1 
ATOM   3764 O  O   . THR A 1 612 ? 182.155 160.142 127.240 1.00 61.38  ? 612  THR A O   1 
ATOM   3765 C  CB  . THR A 1 612 ? 184.887 160.039 128.834 1.00 61.38  ? 612  THR A CB  1 
ATOM   3766 O  OG1 . THR A 1 612 ? 184.109 161.127 129.349 1.00 61.38  ? 612  THR A OG1 1 
ATOM   3767 C  CG2 . THR A 1 612 ? 185.827 160.564 127.768 1.00 61.38  ? 612  THR A CG2 1 
ATOM   3768 N  N   . LEU A 1 613 ? 183.703 159.329 125.846 1.00 59.59  ? 613  LEU A N   1 
ATOM   3769 C  CA  . LEU A 1 613 ? 183.134 159.979 124.676 1.00 59.59  ? 613  LEU A CA  1 
ATOM   3770 C  C   . LEU A 1 613 ? 182.824 158.951 123.601 1.00 59.59  ? 613  LEU A C   1 
ATOM   3771 O  O   . LEU A 1 613 ? 183.672 158.123 123.255 1.00 59.59  ? 613  LEU A O   1 
ATOM   3772 C  CB  . LEU A 1 613 ? 184.084 161.055 124.137 1.00 59.59  ? 613  LEU A CB  1 
ATOM   3773 C  CG  . LEU A 1 613 ? 183.906 161.628 122.731 1.00 59.59  ? 613  LEU A CG  1 
ATOM   3774 C  CD1 . LEU A 1 613 ? 184.425 163.046 122.717 1.00 59.59  ? 613  LEU A CD1 1 
ATOM   3775 C  CD2 . LEU A 1 613 ? 184.662 160.815 121.698 1.00 59.59  ? 613  LEU A CD2 1 
ATOM   3776 N  N   . PHE A 1 614 ? 181.608 159.020 123.068 1.00 61.31  ? 614  PHE A N   1 
ATOM   3777 C  CA  . PHE A 1 614 ? 181.157 158.151 121.989 1.00 61.31  ? 614  PHE A CA  1 
ATOM   3778 C  C   . PHE A 1 614 ? 180.752 159.025 120.812 1.00 61.31  ? 614  PHE A C   1 
ATOM   3779 O  O   . PHE A 1 614 ? 179.936 159.939 120.968 1.00 61.31  ? 614  PHE A O   1 
ATOM   3780 C  CB  . PHE A 1 614 ? 179.991 157.274 122.447 1.00 61.31  ? 614  PHE A CB  1 
ATOM   3781 C  CG  . PHE A 1 614 ? 180.353 156.305 123.533 1.00 61.31  ? 614  PHE A CG  1 
ATOM   3782 C  CD1 . PHE A 1 614 ? 181.638 155.818 123.639 1.00 61.31  ? 614  PHE A CD1 1 
ATOM   3783 C  CD2 . PHE A 1 614 ? 179.411 155.886 124.449 1.00 61.31  ? 614  PHE A CD2 1 
ATOM   3784 C  CE1 . PHE A 1 614 ? 181.976 154.929 124.634 1.00 61.31  ? 614  PHE A CE1 1 
ATOM   3785 C  CE2 . PHE A 1 614 ? 179.743 155.000 125.447 1.00 61.31  ? 614  PHE A CE2 1 
ATOM   3786 C  CZ  . PHE A 1 614 ? 181.027 154.521 125.540 1.00 61.31  ? 614  PHE A CZ  1 
ATOM   3787 N  N   . ALA A 1 615 ? 181.312 158.742 119.641 1.00 66.52  ? 615  ALA A N   1 
ATOM   3788 C  CA  . ALA A 1 615 ? 181.125 159.576 118.465 1.00 66.52  ? 615  ALA A CA  1 
ATOM   3789 C  C   . ALA A 1 615 ? 180.650 158.739 117.285 1.00 66.52  ? 615  ALA A C   1 
ATOM   3790 O  O   . ALA A 1 615 ? 180.856 157.524 117.230 1.00 66.52  ? 615  ALA A O   1 
ATOM   3791 C  CB  . ALA A 1 615 ? 182.420 160.313 118.108 1.00 66.52  ? 615  ALA A CB  1 
ATOM   3792 N  N   . ARG A 1 616 ? 180.019 159.421 116.325 1.00 70.61  ? 616  ARG A N   1 
ATOM   3793 C  CA  . ARG A 1 616 ? 179.435 158.781 115.145 1.00 70.61  ? 616  ARG A CA  1 
ATOM   3794 C  C   . ARG A 1 616 ? 178.394 157.741 115.547 1.00 70.61  ? 616  ARG A C   1 
ATOM   3795 O  O   . ARG A 1 616 ? 178.483 156.567 115.184 1.00 70.61  ? 616  ARG A O   1 
ATOM   3796 C  CB  . ARG A 1 616 ? 180.513 158.156 114.255 1.00 70.61  ? 616  ARG A CB  1 
ATOM   3797 C  CG  . ARG A 1 616 ? 181.804 158.947 114.175 1.00 70.61  ? 616  ARG A CG  1 
ATOM   3798 C  CD  . ARG A 1 616 ? 181.648 160.165 113.286 1.00 70.61  ? 616  ARG A CD  1 
ATOM   3799 N  NE  . ARG A 1 616 ? 181.491 159.799 111.884 1.00 70.61  ? 616  ARG A NE  1 
ATOM   3800 C  CZ  . ARG A 1 616 ? 182.473 159.361 111.109 1.00 70.61  ? 616  ARG A CZ  1 
ATOM   3801 N  NH1 . ARG A 1 616 ? 183.707 159.224 111.566 1.00 70.61  ? 616  ARG A NH1 1 
ATOM   3802 N  NH2 . ARG A 1 616 ? 182.211 159.053 109.842 1.00 70.61  ? 616  ARG A NH2 1 
ATOM   3803 N  N   . LEU A 1 617 ? 177.391 158.177 116.302 1.00 68.49  ? 617  LEU A N   1 
ATOM   3804 C  CA  . LEU A 1 617 ? 176.413 157.274 116.888 1.00 68.49  ? 617  LEU A CA  1 
ATOM   3805 C  C   . LEU A 1 617 ? 175.031 157.469 116.281 1.00 68.49  ? 617  LEU A C   1 
ATOM   3806 O  O   . LEU A 1 617 ? 174.553 158.597 116.136 1.00 68.49  ? 617  LEU A O   1 
ATOM   3807 C  CB  . LEU A 1 617 ? 176.334 157.470 118.401 1.00 68.49  ? 617  LEU A CB  1 
ATOM   3808 C  CG  . LEU A 1 617 ? 177.095 156.446 119.237 1.00 68.49  ? 617  LEU A CG  1 
ATOM   3809 C  CD1 . LEU A 1 617 ? 178.564 156.776 119.255 1.00 68.49  ? 617  LEU A CD1 1 
ATOM   3810 C  CD2 . LEU A 1 617 ? 176.541 156.418 120.642 1.00 68.49  ? 617  LEU A CD2 1 
ATOM   3811 N  N   . THR A 1 618 ? 174.401 156.355 115.929 1.00 73.70  ? 618  THR A N   1 
ATOM   3812 C  CA  . THR A 1 618 ? 172.997 156.321 115.567 1.00 73.70  ? 618  THR A CA  1 
ATOM   3813 C  C   . THR A 1 618 ? 172.142 156.245 116.829 1.00 73.70  ? 618  THR A C   1 
ATOM   3814 O  O   . THR A 1 618 ? 172.624 155.835 117.887 1.00 73.70  ? 618  THR A O   1 
ATOM   3815 C  CB  . THR A 1 618 ? 172.722 155.122 114.667 1.00 73.70  ? 618  THR A CB  1 
ATOM   3816 O  OG1 . THR A 1 618 ? 173.038 153.916 115.373 1.00 73.70  ? 618  THR A OG1 1 
ATOM   3817 C  CG2 . THR A 1 618 ? 173.572 155.199 113.409 1.00 73.70  ? 618  THR A CG2 1 
ATOM   3818 N  N   . PRO A 1 619 ? 170.869 156.648 116.752 1.00 75.41  ? 619  PRO A N   1 
ATOM   3819 C  CA  . PRO A 1 619 ? 170.030 156.622 117.964 1.00 75.41  ? 619  PRO A CA  1 
ATOM   3820 C  C   . PRO A 1 619 ? 169.951 155.255 118.626 1.00 75.41  ? 619  PRO A C   1 
ATOM   3821 O  O   . PRO A 1 619 ? 169.934 155.169 119.863 1.00 75.41  ? 619  PRO A O   1 
ATOM   3822 C  CB  . PRO A 1 619 ? 168.665 157.087 117.442 1.00 75.41  ? 619  PRO A CB  1 
ATOM   3823 C  CG  . PRO A 1 619 ? 169.003 157.962 116.291 1.00 75.41  ? 619  PRO A CG  1 
ATOM   3824 C  CD  . PRO A 1 619 ? 170.179 157.304 115.628 1.00 75.41  ? 619  PRO A CD  1 
ATOM   3825 N  N   . MET A 1 620 ? 169.909 154.178 117.838 1.00 78.99  ? 620  MET A N   1 
ATOM   3826 C  CA  . MET A 1 620 ? 169.914 152.845 118.428 1.00 78.99  ? 620  MET A CA  1 
ATOM   3827 C  C   . MET A 1 620 ? 171.210 152.589 119.186 1.00 78.99  ? 620  MET A C   1 
ATOM   3828 O  O   . MET A 1 620 ? 171.210 151.906 120.216 1.00 78.99  ? 620  MET A O   1 
ATOM   3829 C  CB  . MET A 1 620 ? 169.695 151.782 117.352 1.00 78.99  ? 620  MET A CB  1 
ATOM   3830 C  CG  . MET A 1 620 ? 168.769 152.215 116.228 1.00 78.99  ? 620  MET A CG  1 
ATOM   3831 S  SD  . MET A 1 620 ? 169.552 153.337 115.058 1.00 78.99  ? 620  MET A SD  1 
ATOM   3832 C  CE  . MET A 1 620 ? 170.577 152.189 114.141 1.00 78.99  ? 620  MET A CE  1 
ATOM   3833 N  N   . HIS A 1 621 ? 172.324 153.137 118.695 1.00 78.30  ? 621  HIS A N   1 
ATOM   3834 C  CA  . HIS A 1 621 ? 173.580 153.031 119.429 1.00 78.30  ? 621  HIS A CA  1 
ATOM   3835 C  C   . HIS A 1 621 ? 173.478 153.707 120.789 1.00 78.30  ? 621  HIS A C   1 
ATOM   3836 O  O   . HIS A 1 621 ? 173.934 153.159 121.800 1.00 78.30  ? 621  HIS A O   1 
ATOM   3837 C  CB  . HIS A 1 621 ? 174.718 153.643 118.614 1.00 78.30  ? 621  HIS A CB  1 
ATOM   3838 C  CG  . HIS A 1 621 ? 175.084 152.855 117.397 1.00 78.30  ? 621  HIS A CG  1 
ATOM   3839 N  ND1 . HIS A 1 621 ? 175.565 153.443 116.247 1.00 78.30  ? 621  HIS A ND1 1 
ATOM   3840 C  CD2 . HIS A 1 621 ? 175.046 151.524 117.151 1.00 78.30  ? 621  HIS A CD2 1 
ATOM   3841 C  CE1 . HIS A 1 621 ? 175.805 152.509 115.344 1.00 78.30  ? 621  HIS A CE1 1 
ATOM   3842 N  NE2 . HIS A 1 621 ? 175.498 151.336 115.867 1.00 78.30  ? 621  HIS A NE2 1 
ATOM   3843 N  N   . LYS A 1 622 ? 172.877 154.898 120.834 1.00 69.62  ? 622  LYS A N   1 
ATOM   3844 C  CA  . LYS A 1 622 ? 172.712 155.601 122.102 1.00 69.62  ? 622  LYS A CA  1 
ATOM   3845 C  C   . LYS A 1 622 ? 171.839 154.800 123.056 1.00 69.62  ? 622  LYS A C   1 
ATOM   3846 O  O   . LYS A 1 622 ? 172.155 154.664 124.246 1.00 69.62  ? 622  LYS A O   1 
ATOM   3847 C  CB  . LYS A 1 622 ? 172.111 156.984 121.856 1.00 69.62  ? 622  LYS A CB  1 
ATOM   3848 C  CG  . LYS A 1 622 ? 172.954 157.883 120.972 1.00 69.62  ? 622  LYS A CG  1 
ATOM   3849 C  CD  . LYS A 1 622 ? 172.496 159.327 121.060 1.00 69.62  ? 622  LYS A CD  1 
ATOM   3850 C  CE  . LYS A 1 622 ? 172.646 160.031 119.723 1.00 69.62  ? 622  LYS A CE  1 
ATOM   3851 N  NZ  . LYS A 1 622 ? 172.344 161.482 119.822 1.00 69.62  ? 622  LYS A NZ  1 
ATOM   3852 N  N   . GLU A 1 623 ? 170.731 154.258 122.548 1.00 73.12  ? 623  GLU A N   1 
ATOM   3853 C  CA  . GLU A 1 623 ? 169.845 153.465 123.394 1.00 73.12  ? 623  GLU A CA  1 
ATOM   3854 C  C   . GLU A 1 623 ? 170.560 152.240 123.945 1.00 73.12  ? 623  GLU A C   1 
ATOM   3855 O  O   . GLU A 1 623 ? 170.456 151.933 125.140 1.00 73.12  ? 623  GLU A O   1 
ATOM   3856 C  CB  . GLU A 1 623 ? 168.607 153.048 122.605 1.00 73.12  ? 623  GLU A CB  1 
ATOM   3857 C  CG  . GLU A 1 623 ? 167.374 152.844 123.457 1.00 73.12  ? 623  GLU A CG  1 
ATOM   3858 C  CD  . GLU A 1 623 ? 166.098 152.978 122.659 1.00 73.12  ? 623  GLU A CD  1 
ATOM   3859 O  OE1 . GLU A 1 623 ? 165.010 153.009 123.272 1.00 73.12  ? 623  GLU A OE1 1 
ATOM   3860 O  OE2 . GLU A 1 623 ? 166.184 153.052 121.416 1.00 73.12  ? 623  GLU A OE2 1 
ATOM   3861 N  N   . ARG A 1 624 ? 171.299 151.533 123.090 1.00 76.33  ? 624  ARG A N   1 
ATOM   3862 C  CA  . ARG A 1 624 ? 172.009 150.342 123.537 1.00 76.33  ? 624  ARG A CA  1 
ATOM   3863 C  C   . ARG A 1 624 ? 173.065 150.689 124.575 1.00 76.33  ? 624  ARG A C   1 
ATOM   3864 O  O   . ARG A 1 624 ? 173.226 149.974 125.570 1.00 76.33  ? 624  ARG A O   1 
ATOM   3865 C  CB  . ARG A 1 624 ? 172.640 149.628 122.344 1.00 76.33  ? 624  ARG A CB  1 
ATOM   3866 C  CG  . ARG A 1 624 ? 173.279 148.299 122.692 1.00 76.33  ? 624  ARG A CG  1 
ATOM   3867 C  CD  . ARG A 1 624 ? 173.857 147.635 121.460 1.00 76.33  ? 624  ARG A CD  1 
ATOM   3868 N  NE  . ARG A 1 624 ? 174.479 146.356 121.773 1.00 76.33  ? 624  ARG A NE  1 
ATOM   3869 C  CZ  . ARG A 1 624 ? 175.067 145.575 120.879 1.00 76.33  ? 624  ARG A CZ  1 
ATOM   3870 N  NH1 . ARG A 1 624 ? 175.135 145.915 119.603 1.00 76.33  ? 624  ARG A NH1 1 
ATOM   3871 N  NH2 . ARG A 1 624 ? 175.601 144.423 121.275 1.00 76.33  ? 624  ARG A NH2 1 
ATOM   3872 N  N   . ILE A 1 625 ? 173.792 151.789 124.367 1.00 68.98  ? 625  ILE A N   1 
ATOM   3873 C  CA  . ILE A 1 625 ? 174.844 152.168 125.304 1.00 68.98  ? 625  ILE A CA  1 
ATOM   3874 C  C   . ILE A 1 625 ? 174.250 152.550 126.653 1.00 68.98  ? 625  ILE A C   1 
ATOM   3875 O  O   . ILE A 1 625 ? 174.786 152.189 127.708 1.00 68.98  ? 625  ILE A O   1 
ATOM   3876 C  CB  . ILE A 1 625 ? 175.702 153.297 124.708 1.00 68.98  ? 625  ILE A CB  1 
ATOM   3877 C  CG1 . ILE A 1 625 ? 176.729 152.703 123.744 1.00 68.98  ? 625  ILE A CG1 1 
ATOM   3878 C  CG2 . ILE A 1 625 ? 176.382 154.091 125.804 1.00 68.98  ? 625  ILE A CG2 1 
ATOM   3879 C  CD1 . ILE A 1 625 ? 177.322 153.696 122.789 1.00 68.98  ? 625  ILE A CD1 1 
ATOM   3880 N  N   . VAL A 1 626 ? 173.129 153.274 126.646 1.00 66.34  ? 626  VAL A N   1 
ATOM   3881 C  CA  . VAL A 1 626 ? 172.478 153.621 127.907 1.00 66.34  ? 626  VAL A CA  1 
ATOM   3882 C  C   . VAL A 1 626 ? 171.999 152.365 128.627 1.00 66.34  ? 626  VAL A C   1 
ATOM   3883 O  O   . VAL A 1 626 ? 172.191 152.214 129.842 1.00 66.34  ? 626  VAL A O   1 
ATOM   3884 C  CB  . VAL A 1 626 ? 171.325 154.609 127.658 1.00 66.34  ? 626  VAL A CB  1 
ATOM   3885 C  CG1 . VAL A 1 626 ? 170.386 154.627 128.842 1.00 66.34  ? 626  VAL A CG1 1 
ATOM   3886 C  CG2 . VAL A 1 626 ? 171.870 155.999 127.391 1.00 66.34  ? 626  VAL A CG2 1 
ATOM   3887 N  N   . THR A 1 627 ? 171.377 151.438 127.892 1.00 70.43  ? 627  THR A N   1 
ATOM   3888 C  CA  . THR A 1 627 ? 170.879 150.219 128.523 1.00 70.43  ? 627  THR A CA  1 
ATOM   3889 C  C   . THR A 1 627 ? 172.018 149.383 129.092 1.00 70.43  ? 627  THR A C   1 
ATOM   3890 O  O   . THR A 1 627 ? 171.875 148.768 130.155 1.00 70.43  ? 627  THR A O   1 
ATOM   3891 C  CB  . THR A 1 627 ? 170.064 149.398 127.526 1.00 70.43  ? 627  THR A CB  1 
ATOM   3892 O  OG1 . THR A 1 627 ? 170.789 149.282 126.297 1.00 70.43  ? 627  THR A OG1 1 
ATOM   3893 C  CG2 . THR A 1 627 ? 168.724 150.066 127.261 1.00 70.43  ? 627  THR A CG2 1 
ATOM   3894 N  N   . LEU A 1 628 ? 173.155 149.340 128.397 1.00 73.36  ? 628  LEU A N   1 
ATOM   3895 C  CA  . LEU A 1 628 ? 174.301 148.595 128.907 1.00 73.36  ? 628  LEU A CA  1 
ATOM   3896 C  C   . LEU A 1 628 ? 174.929 149.278 130.115 1.00 73.36  ? 628  LEU A C   1 
ATOM   3897 O  O   . LEU A 1 628 ? 175.418 148.596 131.024 1.00 73.36  ? 628  LEU A O   1 
ATOM   3898 C  CB  . LEU A 1 628 ? 175.337 148.405 127.803 1.00 73.36  ? 628  LEU A CB  1 
ATOM   3899 C  CG  . LEU A 1 628 ? 174.865 147.514 126.657 1.00 73.36  ? 628  LEU A CG  1 
ATOM   3900 C  CD1 . LEU A 1 628 ? 175.892 147.489 125.547 1.00 73.36  ? 628  LEU A CD1 1 
ATOM   3901 C  CD2 . LEU A 1 628 ? 174.582 146.116 127.163 1.00 73.36  ? 628  LEU A CD2 1 
ATOM   3902 N  N   . LEU A 1 629 ? 174.941 150.612 130.144 1.00 65.39  ? 629  LEU A N   1 
ATOM   3903 C  CA  . LEU A 1 629 ? 175.424 151.310 131.329 1.00 65.39  ? 629  LEU A CA  1 
ATOM   3904 C  C   . LEU A 1 629 ? 174.504 151.083 132.519 1.00 65.39  ? 629  LEU A C   1 
ATOM   3905 O  O   . LEU A 1 629 ? 174.960 151.101 133.668 1.00 65.39  ? 629  LEU A O   1 
ATOM   3906 C  CB  . LEU A 1 629 ? 175.564 152.805 131.045 1.00 65.39  ? 629  LEU A CB  1 
ATOM   3907 C  CG  . LEU A 1 629 ? 176.764 153.232 130.203 1.00 65.39  ? 629  LEU A CG  1 
ATOM   3908 C  CD1 . LEU A 1 629 ? 176.735 154.729 129.964 1.00 65.39  ? 629  LEU A CD1 1 
ATOM   3909 C  CD2 . LEU A 1 629 ? 178.058 152.820 130.873 1.00 65.39  ? 629  LEU A CD2 1 
ATOM   3910 N  N   . LYS A 1 630 ? 173.211 150.874 132.264 1.00 64.35  ? 630  LYS A N   1 
ATOM   3911 C  CA  . LYS A 1 630 ? 172.260 150.637 133.346 1.00 64.35  ? 630  LYS A CA  1 
ATOM   3912 C  C   . LYS A 1 630 ? 172.564 149.378 134.151 1.00 64.35  ? 630  LYS A C   1 
ATOM   3913 O  O   . LYS A 1 630 ? 172.123 149.275 135.301 1.00 64.35  ? 630  LYS A O   1 
ATOM   3914 C  CB  . LYS A 1 630 ? 170.846 150.522 132.784 1.00 64.35  ? 630  LYS A CB  1 
ATOM   3915 C  CG  . LYS A 1 630 ? 170.169 151.831 132.469 1.00 64.35  ? 630  LYS A CG  1 
ATOM   3916 C  CD  . LYS A 1 630 ? 168.785 151.572 131.902 1.00 64.35  ? 630  LYS A CD  1 
ATOM   3917 C  CE  . LYS A 1 630 ? 167.940 150.755 132.865 1.00 64.35  ? 630  LYS A CE  1 
ATOM   3918 N  NZ  . LYS A 1 630 ? 166.555 150.545 132.367 1.00 64.35  ? 630  LYS A NZ  1 
ATOM   3919 N  N   . ARG A 1 631 ? 173.301 148.422 133.578 1.00 73.14  ? 631  ARG A N   1 
ATOM   3920 C  CA  . ARG A 1 631 ? 173.336 147.072 134.139 1.00 73.14  ? 631  ARG A CA  1 
ATOM   3921 C  C   . ARG A 1 631 ? 173.983 147.043 135.520 1.00 73.14  ? 631  ARG A C   1 
ATOM   3922 O  O   . ARG A 1 631 ? 173.432 146.462 136.462 1.00 73.14  ? 631  ARG A O   1 
ATOM   3923 C  CB  . ARG A 1 631 ? 174.070 146.127 133.188 1.00 73.14  ? 631  ARG A CB  1 
ATOM   3924 C  CG  . ARG A 1 631 ? 173.279 145.762 131.946 1.00 73.14  ? 631  ARG A CG  1 
ATOM   3925 C  CD  . ARG A 1 631 ? 173.989 144.696 131.134 1.00 73.14  ? 631  ARG A CD  1 
ATOM   3926 N  NE  . ARG A 1 631 ? 173.371 144.514 129.827 1.00 73.14  ? 631  ARG A NE  1 
ATOM   3927 C  CZ  . ARG A 1 631 ? 172.385 143.665 129.574 1.00 73.14  ? 631  ARG A CZ  1 
ATOM   3928 N  NH1 . ARG A 1 631 ? 171.875 142.896 130.522 1.00 73.14  ? 631  ARG A NH1 1 
ATOM   3929 N  NH2 . ARG A 1 631 ? 171.898 143.585 128.340 1.00 73.14  ? 631  ARG A NH2 1 
ATOM   3930 N  N   . GLU A 1 632 ? 175.153 147.664 135.662 1.00 70.90  ? 632  GLU A N   1 
ATOM   3931 C  CA  . GLU A 1 632 ? 175.945 147.480 136.873 1.00 70.90  ? 632  GLU A CA  1 
ATOM   3932 C  C   . GLU A 1 632 ? 175.323 148.118 138.108 1.00 70.90  ? 632  GLU A C   1 
ATOM   3933 O  O   . GLU A 1 632 ? 175.791 147.850 139.218 1.00 70.90  ? 632  GLU A O   1 
ATOM   3934 C  CB  . GLU A 1 632 ? 177.356 148.024 136.657 1.00 70.90  ? 632  GLU A CB  1 
ATOM   3935 C  CG  . GLU A 1 632 ? 178.343 146.981 136.146 1.00 70.90  ? 632  GLU A CG  1 
ATOM   3936 C  CD  . GLU A 1 632 ? 178.000 146.466 134.759 1.00 70.90  ? 632  GLU A CD  1 
ATOM   3937 O  OE1 . GLU A 1 632 ? 177.236 147.141 134.036 1.00 70.90  ? 632  GLU A OE1 1 
ATOM   3938 O  OE2 . GLU A 1 632 ? 178.494 145.380 134.390 1.00 70.90  ? 632  GLU A OE2 1 
ATOM   3939 N  N   . GLY A 1 633 ? 174.293 148.943 137.952 1.00 65.84  ? 633  GLY A N   1 
ATOM   3940 C  CA  . GLY A 1 633 ? 173.632 149.524 139.104 1.00 65.84  ? 633  GLY A CA  1 
ATOM   3941 C  C   . GLY A 1 633 ? 173.609 151.037 139.100 1.00 65.84  ? 633  GLY A C   1 
ATOM   3942 O  O   . GLY A 1 633 ? 172.863 151.654 139.867 1.00 65.84  ? 633  GLY A O   1 
ATOM   3943 N  N   . HIS A 1 634 ? 174.427 151.647 138.248 1.00 56.87  ? 634  HIS A N   1 
ATOM   3944 C  CA  . HIS A 1 634 ? 174.444 153.098 138.137 1.00 56.87  ? 634  HIS A CA  1 
ATOM   3945 C  C   . HIS A 1 634 ? 173.111 153.604 137.606 1.00 56.87  ? 634  HIS A C   1 
ATOM   3946 O  O   . HIS A 1 634 ? 172.511 153.002 136.713 1.00 56.87  ? 634  HIS A O   1 
ATOM   3947 C  CB  . HIS A 1 634 ? 175.576 153.549 137.216 1.00 56.87  ? 634  HIS A CB  1 
ATOM   3948 C  CG  . HIS A 1 634 ? 176.906 152.958 137.560 1.00 56.87  ? 634  HIS A CG  1 
ATOM   3949 N  ND1 . HIS A 1 634 ? 177.394 152.923 138.848 1.00 56.87  ? 634  HIS A ND1 1 
ATOM   3950 C  CD2 . HIS A 1 634 ? 177.853 152.382 136.783 1.00 56.87  ? 634  HIS A CD2 1 
ATOM   3951 C  CE1 . HIS A 1 634 ? 178.584 152.350 138.850 1.00 56.87  ? 634  HIS A CE1 1 
ATOM   3952 N  NE2 . HIS A 1 634 ? 178.886 152.012 137.609 1.00 56.87  ? 634  HIS A NE2 1 
ATOM   3953 N  N   . VAL A 1 635 ? 172.643 154.715 138.168 1.00 50.34  ? 635  VAL A N   1 
ATOM   3954 C  CA  . VAL A 1 635 ? 171.425 155.369 137.705 1.00 50.34  ? 635  VAL A CA  1 
ATOM   3955 C  C   . VAL A 1 635 ? 171.843 156.334 136.602 1.00 50.34  ? 635  VAL A C   1 
ATOM   3956 O  O   . VAL A 1 635 ? 172.312 157.440 136.871 1.00 50.34  ? 635  VAL A O   1 
ATOM   3957 C  CB  . VAL A 1 635 ? 170.693 156.080 138.842 1.00 50.34  ? 635  VAL A CB  1 
ATOM   3958 C  CG1 . VAL A 1 635 ? 169.492 156.838 138.310 1.00 50.34  ? 635  VAL A CG1 1 
ATOM   3959 C  CG2 . VAL A 1 635 ? 170.259 155.077 139.894 1.00 50.34  ? 635  VAL A CG2 1 
ATOM   3960 N  N   . VAL A 1 636 ? 171.682 155.909 135.354 1.00 48.26  ? 636  VAL A N   1 
ATOM   3961 C  CA  . VAL A 1 636 ? 172.150 156.670 134.203 1.00 48.26  ? 636  VAL A CA  1 
ATOM   3962 C  C   . VAL A 1 636 ? 171.015 157.533 133.681 1.00 48.26  ? 636  VAL A C   1 
ATOM   3963 O  O   . VAL A 1 636 ? 169.901 157.045 133.461 1.00 48.26  ? 636  VAL A O   1 
ATOM   3964 C  CB  . VAL A 1 636 ? 172.674 155.734 133.105 1.00 48.26  ? 636  VAL A CB  1 
ATOM   3965 C  CG1 . VAL A 1 636 ? 172.975 156.519 131.848 1.00 48.26  ? 636  VAL A CG1 1 
ATOM   3966 C  CG2 . VAL A 1 636 ? 173.909 155.006 133.585 1.00 48.26  ? 636  VAL A CG2 1 
ATOM   3967 N  N   . GLY A 1 637 ? 171.294 158.815 133.484 1.00 46.03  ? 637  GLY A N   1 
ATOM   3968 C  CA  . GLY A 1 637 ? 170.338 159.751 132.911 1.00 46.03  ? 637  GLY A CA  1 
ATOM   3969 C  C   . GLY A 1 637 ? 170.823 160.231 131.558 1.00 46.03  ? 637  GLY A C   1 
ATOM   3970 O  O   . GLY A 1 637 ? 172.012 160.503 131.376 1.00 46.03  ? 637  GLY A O   1 
ATOM   3971 N  N   . PHE A 1 638 ? 169.900 160.334 130.608 1.00 50.11  ? 638  PHE A N   1 
ATOM   3972 C  CA  . PHE A 1 638 ? 170.206 160.800 129.265 1.00 50.11  ? 638  PHE A CA  1 
ATOM   3973 C  C   . PHE A 1 638 ? 169.530 162.143 129.039 1.00 50.11  ? 638  PHE A C   1 
ATOM   3974 O  O   . PHE A 1 638 ? 168.352 162.311 129.365 1.00 50.11  ? 638  PHE A O   1 
ATOM   3975 C  CB  . PHE A 1 638 ? 169.748 159.793 128.210 1.00 50.11  ? 638  PHE A CB  1 
ATOM   3976 C  CG  . PHE A 1 638 ? 170.169 160.147 126.811 1.00 50.11  ? 638  PHE A CG  1 
ATOM   3977 C  CD1 . PHE A 1 638 ? 171.415 159.779 126.336 1.00 50.11  ? 638  PHE A CD1 1 
ATOM   3978 C  CD2 . PHE A 1 638 ? 169.323 160.846 125.973 1.00 50.11  ? 638  PHE A CD2 1 
ATOM   3979 C  CE1 . PHE A 1 638 ? 171.805 160.103 125.055 1.00 50.11  ? 638  PHE A CE1 1 
ATOM   3980 C  CE2 . PHE A 1 638 ? 169.709 161.172 124.692 1.00 50.11  ? 638  PHE A CE2 1 
ATOM   3981 C  CZ  . PHE A 1 638 ? 170.951 160.800 124.233 1.00 50.11  ? 638  PHE A CZ  1 
ATOM   3982 N  N   . MET A 1 639 ? 170.279 163.095 128.492 1.00 48.65  ? 639  MET A N   1 
ATOM   3983 C  CA  . MET A 1 639 ? 169.775 164.430 128.199 1.00 48.65  ? 639  MET A CA  1 
ATOM   3984 C  C   . MET A 1 639 ? 169.777 164.630 126.693 1.00 48.65  ? 639  MET A C   1 
ATOM   3985 O  O   . MET A 1 639 ? 170.820 164.483 126.048 1.00 48.65  ? 639  MET A O   1 
ATOM   3986 C  CB  . MET A 1 639 ? 170.624 165.500 128.884 1.00 48.65  ? 639  MET A CB  1 
ATOM   3987 C  CG  . MET A 1 639 ? 170.150 166.912 128.626 1.00 48.65  ? 639  MET A CG  1 
ATOM   3988 S  SD  . MET A 1 639 ? 171.157 168.143 129.463 1.00 48.65  ? 639  MET A SD  1 
ATOM   3989 C  CE  . MET A 1 639 ? 170.152 169.599 129.218 1.00 48.65  ? 639  MET A CE  1 
ATOM   3990 N  N   . GLY A 1 640 ? 168.623 164.964 126.138 1.00 58.71  ? 640  GLY A N   1 
ATOM   3991 C  CA  . GLY A 1 640 ? 168.516 165.162 124.703 1.00 58.71  ? 640  GLY A CA  1 
ATOM   3992 C  C   . GLY A 1 640 ? 167.298 165.981 124.350 1.00 58.71  ? 640  GLY A C   1 
ATOM   3993 O  O   . GLY A 1 640 ? 166.296 165.984 125.072 1.00 58.71  ? 640  GLY A O   1 
ATOM   3994 N  N   . ASP A 1 641 ? 167.387 166.681 123.223 1.00 63.36  ? 641  ASP A N   1 
ATOM   3995 C  CA  . ASP A 1 641 ? 166.290 167.491 122.711 1.00 63.36  ? 641  ASP A CA  1 
ATOM   3996 C  C   . ASP A 1 641 ? 166.143 167.287 121.211 1.00 63.36  ? 641  ASP A C   1 
ATOM   3997 O  O   . ASP A 1 641 ? 165.824 168.218 120.465 1.00 63.36  ? 641  ASP A O   1 
ATOM   3998 C  CB  . ASP A 1 641 ? 166.498 168.968 123.042 1.00 63.36  ? 641  ASP A CB  1 
ATOM   3999 C  CG  . ASP A 1 641 ? 167.801 169.510 122.496 1.00 63.36  ? 641  ASP A CG  1 
ATOM   4000 O  OD1 . ASP A 1 641 ? 168.681 168.700 122.140 1.00 63.36  ? 641  ASP A OD1 1 
ATOM   4001 O  OD2 . ASP A 1 641 ? 167.945 170.747 122.423 1.00 63.36  ? 641  ASP A OD2 1 
ATOM   4002 N  N   . GLY A 1 642 ? 166.375 166.061 120.748 1.00 73.18  ? 642  GLY A N   1 
ATOM   4003 C  CA  . GLY A 1 642 ? 166.286 165.758 119.334 1.00 73.18  ? 642  GLY A CA  1 
ATOM   4004 C  C   . GLY A 1 642 ? 165.048 164.965 118.975 1.00 73.18  ? 642  GLY A C   1 
ATOM   4005 O  O   . GLY A 1 642 ? 164.448 164.316 119.836 1.00 73.18  ? 642  GLY A O   1 
ATOM   4006 N  N   . ILE A 1 643 ? 164.657 165.012 117.700 1.00 76.74  ? 643  ILE A N   1 
ATOM   4007 C  CA  . ILE A 1 643 ? 163.453 164.310 117.263 1.00 76.74  ? 643  ILE A CA  1 
ATOM   4008 C  C   . ILE A 1 643 ? 163.619 162.806 117.444 1.00 76.74  ? 643  ILE A C   1 
ATOM   4009 O  O   . ILE A 1 643 ? 162.712 162.116 117.924 1.00 76.74  ? 643  ILE A O   1 
ATOM   4010 C  CB  . ILE A 1 643 ? 163.124 164.671 115.804 1.00 76.74  ? 643  ILE A CB  1 
ATOM   4011 C  CG1 . ILE A 1 643 ? 162.827 166.166 115.684 1.00 76.74  ? 643  ILE A CG1 1 
ATOM   4012 C  CG2 . ILE A 1 643 ? 161.945 163.852 115.304 1.00 76.74  ? 643  ILE A CG2 1 
ATOM   4013 C  CD1 . ILE A 1 643 ? 162.747 166.659 114.257 1.00 76.74  ? 643  ILE A CD1 1 
ATOM   4014 N  N   . ASN A 1 644 ? 164.780 162.279 117.068 1.00 76.06  ? 644  ASN A N   1 
ATOM   4015 C  CA  . ASN A 1 644 ? 165.070 160.859 117.209 1.00 76.06  ? 644  ASN A CA  1 
ATOM   4016 C  C   . ASN A 1 644 ? 165.701 160.514 118.550 1.00 76.06  ? 644  ASN A C   1 
ATOM   4017 O  O   . ASN A 1 644 ? 166.034 159.346 118.779 1.00 76.06  ? 644  ASN A O   1 
ATOM   4018 C  CB  . ASN A 1 644 ? 165.989 160.394 116.076 1.00 76.06  ? 644  ASN A CB  1 
ATOM   4019 C  CG  . ASN A 1 644 ? 167.171 161.316 115.873 1.00 76.06  ? 644  ASN A CG  1 
ATOM   4020 O  OD1 . ASN A 1 644 ? 167.326 162.309 116.583 1.00 76.06  ? 644  ASN A OD1 1 
ATOM   4021 N  ND2 . ASN A 1 644 ? 168.016 160.991 114.903 1.00 76.06  ? 644  ASN A ND2 1 
ATOM   4022 N  N   . ASP A 1 645 ? 165.877 161.494 119.437 1.00 72.69  ? 645  ASP A N   1 
ATOM   4023 C  CA  . ASP A 1 645 ? 166.510 161.246 120.726 1.00 72.69  ? 645  ASP A CA  1 
ATOM   4024 C  C   . ASP A 1 645 ? 165.557 160.647 121.749 1.00 72.69  ? 645  ASP A C   1 
ATOM   4025 O  O   . ASP A 1 645 ? 166.016 160.169 122.791 1.00 72.69  ? 645  ASP A O   1 
ATOM   4026 C  CB  . ASP A 1 645 ? 167.099 162.545 121.280 1.00 72.69  ? 645  ASP A CB  1 
ATOM   4027 C  CG  . ASP A 1 645 ? 168.490 162.825 120.753 1.00 72.69  ? 645  ASP A CG  1 
ATOM   4028 O  OD1 . ASP A 1 645 ? 169.247 161.859 120.531 1.00 72.69  ? 645  ASP A OD1 1 
ATOM   4029 O  OD2 . ASP A 1 645 ? 168.828 164.012 120.560 1.00 72.69  ? 645  ASP A OD2 1 
ATOM   4030 N  N   . ALA A 1 646 ? 164.253 160.661 121.477 1.00 66.89  ? 646  ALA A N   1 
ATOM   4031 C  CA  . ALA A 1 646 ? 163.278 160.211 122.469 1.00 66.89  ? 646  ALA A CA  1 
ATOM   4032 C  C   . ALA A 1 646 ? 163.484 158.781 122.963 1.00 66.89  ? 646  ALA A C   1 
ATOM   4033 O  O   . ALA A 1 646 ? 163.349 158.562 124.180 1.00 66.89  ? 646  ALA A O   1 
ATOM   4034 C  CB  . ALA A 1 646 ? 161.862 160.387 121.908 1.00 66.89  ? 646  ALA A CB  1 
ATOM   4035 N  N   . PRO A 1 647 ? 163.769 157.777 122.120 1.00 65.45  ? 647  PRO A N   1 
ATOM   4036 C  CA  . PRO A 1 647 ? 163.936 156.417 122.671 1.00 65.45  ? 647  PRO A CA  1 
ATOM   4037 C  C   . PRO A 1 647 ? 165.055 156.311 123.691 1.00 65.45  ? 647  PRO A C   1 
ATOM   4038 O  O   . PRO A 1 647 ? 164.949 155.525 124.642 1.00 65.45  ? 647  PRO A O   1 
ATOM   4039 C  CB  . PRO A 1 647 ? 164.207 155.546 121.436 1.00 65.45  ? 647  PRO A CB  1 
ATOM   4040 C  CG  . PRO A 1 647 ? 164.253 156.430 120.275 1.00 65.45  ? 647  PRO A CG  1 
ATOM   4041 C  CD  . PRO A 1 647 ? 163.908 157.818 120.653 1.00 65.45  ? 647  PRO A CD  1 
ATOM   4042 N  N   . ALA A 1 648 ? 166.129 157.084 123.524 1.00 61.50  ? 648  ALA A N   1 
ATOM   4043 C  CA  . ALA A 1 648 ? 167.174 157.113 124.541 1.00 61.50  ? 648  ALA A CA  1 
ATOM   4044 C  C   . ALA A 1 648 ? 166.638 157.661 125.856 1.00 61.50  ? 648  ALA A C   1 
ATOM   4045 O  O   . ALA A 1 648 ? 167.002 157.177 126.934 1.00 61.50  ? 648  ALA A O   1 
ATOM   4046 C  CB  . ALA A 1 648 ? 168.360 157.942 124.053 1.00 61.50  ? 648  ALA A CB  1 
ATOM   4047 N  N   . LEU A 1 649 ? 165.775 158.677 125.787 1.00 60.53  ? 649  LEU A N   1 
ATOM   4048 C  CA  . LEU A 1 649 ? 165.127 159.186 126.990 1.00 60.53  ? 649  LEU A CA  1 
ATOM   4049 C  C   . LEU A 1 649 ? 164.263 158.114 127.636 1.00 60.53  ? 649  LEU A C   1 
ATOM   4050 O  O   . LEU A 1 649 ? 164.203 158.007 128.866 1.00 60.53  ? 649  LEU A O   1 
ATOM   4051 C  CB  . LEU A 1 649 ? 164.285 160.414 126.649 1.00 60.53  ? 649  LEU A CB  1 
ATOM   4052 C  CG  . LEU A 1 649 ? 165.020 161.630 126.089 1.00 60.53  ? 649  LEU A CG  1 
ATOM   4053 C  CD1 . LEU A 1 649 ? 164.099 162.829 126.013 1.00 60.53  ? 649  LEU A CD1 1 
ATOM   4054 C  CD2 . LEU A 1 649 ? 166.209 161.949 126.954 1.00 60.53  ? 649  LEU A CD2 1 
ATOM   4055 N  N   . ARG A 1 650 ? 163.575 157.316 126.818 1.00 64.85  ? 650  ARG A N   1 
ATOM   4056 C  CA  . ARG A 1 650 ? 162.729 156.256 127.359 1.00 64.85  ? 650  ARG A CA  1 
ATOM   4057 C  C   . ARG A 1 650 ? 163.557 155.172 128.040 1.00 64.85  ? 650  ARG A C   1 
ATOM   4058 O  O   . ARG A 1 650 ? 163.162 154.650 129.088 1.00 64.85  ? 650  ARG A O   1 
ATOM   4059 C  CB  . ARG A 1 650 ? 161.869 155.652 126.251 1.00 64.85  ? 650  ARG A CB  1 
ATOM   4060 C  CG  . ARG A 1 650 ? 160.504 156.301 126.104 1.00 64.85  ? 650  ARG A CG  1 
ATOM   4061 C  CD  . ARG A 1 650 ? 159.567 155.423 125.296 1.00 64.85  ? 650  ARG A CD  1 
ATOM   4062 N  NE  . ARG A 1 650 ? 160.043 155.234 123.932 1.00 64.85  ? 650  ARG A NE  1 
ATOM   4063 C  CZ  . ARG A 1 650 ? 159.951 156.144 122.972 1.00 64.85  ? 650  ARG A CZ  1 
ATOM   4064 N  NH1 . ARG A 1 650 ? 159.396 157.325 123.188 1.00 64.85  ? 650  ARG A NH1 1 
ATOM   4065 N  NH2 . ARG A 1 650 ? 160.426 155.859 121.762 1.00 64.85  ? 650  ARG A NH2 1 
ATOM   4066 N  N   . ALA A 1 651 ? 164.706 154.819 127.461 1.00 64.48  ? 651  ALA A N   1 
ATOM   4067 C  CA  . ALA A 1 651 ? 165.480 153.698 127.988 1.00 64.48  ? 651  ALA A CA  1 
ATOM   4068 C  C   . ALA A 1 651 ? 166.120 154.015 129.334 1.00 64.48  ? 651  ALA A C   1 
ATOM   4069 O  O   . ALA A 1 651 ? 166.150 153.152 130.218 1.00 64.48  ? 651  ALA A O   1 
ATOM   4070 C  CB  . ALA A 1 651 ? 166.556 153.280 126.988 1.00 64.48  ? 651  ALA A CB  1 
ATOM   4071 N  N   . ALA A 1 652 ? 166.626 155.231 129.513 1.00 56.21  ? 652  ALA A N   1 
ATOM   4072 C  CA  . ALA A 1 652 ? 167.435 155.552 130.679 1.00 56.21  ? 652  ALA A CA  1 
ATOM   4073 C  C   . ALA A 1 652 ? 166.602 155.543 131.956 1.00 56.21  ? 652  ALA A C   1 
ATOM   4074 O  O   . ALA A 1 652 ? 165.369 155.554 131.928 1.00 56.21  ? 652  ALA A O   1 
ATOM   4075 C  CB  . ALA A 1 652 ? 168.102 156.914 130.503 1.00 56.21  ? 652  ALA A CB  1 
ATOM   4076 N  N   . ASP A 1 653 ? 167.304 155.506 133.095 1.00 55.23  ? 653  ASP A N   1 
ATOM   4077 C  CA  . ASP A 1 653 ? 166.630 155.577 134.388 1.00 55.23  ? 653  ASP A CA  1 
ATOM   4078 C  C   . ASP A 1 653 ? 165.902 156.898 134.563 1.00 55.23  ? 653  ASP A C   1 
ATOM   4079 O  O   . ASP A 1 653 ? 164.892 156.961 135.272 1.00 55.23  ? 653  ASP A O   1 
ATOM   4080 C  CB  . ASP A 1 653 ? 167.633 155.388 135.527 1.00 55.23  ? 653  ASP A CB  1 
ATOM   4081 C  CG  . ASP A 1 653 ? 168.213 153.995 135.567 1.00 55.23  ? 653  ASP A CG  1 
ATOM   4082 O  OD1 . ASP A 1 653 ? 168.599 153.531 136.661 1.00 55.23  ? 653  ASP A OD1 1 
ATOM   4083 O  OD2 . ASP A 1 653 ? 168.283 153.357 134.500 1.00 55.23  ? 653  ASP A OD2 1 
ATOM   4084 N  N   . ILE A 1 654 ? 166.400 157.958 133.938 1.00 47.81  ? 654  ILE A N   1 
ATOM   4085 C  CA  . ILE A 1 654 ? 165.786 159.274 134.033 1.00 47.81  ? 654  ILE A CA  1 
ATOM   4086 C  C   . ILE A 1 654 ? 166.086 160.029 132.749 1.00 47.81  ? 654  ILE A C   1 
ATOM   4087 O  O   . ILE A 1 654 ? 167.246 160.184 132.362 1.00 47.81  ? 654  ILE A O   1 
ATOM   4088 C  CB  . ILE A 1 654 ? 166.291 160.029 135.278 1.00 47.81  ? 654  ILE A CB  1 
ATOM   4089 C  CG1 . ILE A 1 654 ? 165.944 161.508 135.196 1.00 47.81  ? 654  ILE A CG1 1 
ATOM   4090 C  CG2 . ILE A 1 654 ? 167.783 159.840 135.455 1.00 47.81  ? 654  ILE A CG2 1 
ATOM   4091 C  CD1 . ILE A 1 654 ? 165.932 162.167 136.536 1.00 47.81  ? 654  ILE A CD1 1 
ATOM   4092 N  N   . GLY A 1 655 ? 165.038 160.494 132.083 1.00 49.91  ? 655  GLY A N   1 
ATOM   4093 C  CA  . GLY A 1 655 ? 165.224 161.175 130.820 1.00 49.91  ? 655  GLY A CA  1 
ATOM   4094 C  C   . GLY A 1 655 ? 165.002 162.665 130.928 1.00 49.91  ? 655  GLY A C   1 
ATOM   4095 O  O   . GLY A 1 655 ? 163.886 163.112 131.202 1.00 49.91  ? 655  GLY A O   1 
ATOM   4096 N  N   . ILE A 1 656 ? 166.052 163.446 130.708 1.00 47.03  ? 656  ILE A N   1 
ATOM   4097 C  CA  . ILE A 1 656 ? 165.997 164.895 130.849 1.00 47.03  ? 656  ILE A CA  1 
ATOM   4098 C  C   . ILE A 1 656 ? 165.864 165.513 129.467 1.00 47.03  ? 656  ILE A C   1 
ATOM   4099 O  O   . ILE A 1 656 ? 166.702 165.277 128.590 1.00 47.03  ? 656  ILE A O   1 
ATOM   4100 C  CB  . ILE A 1 656 ? 167.243 165.427 131.575 1.00 47.03  ? 656  ILE A CB  1 
ATOM   4101 C  CG1 . ILE A 1 656 ? 167.590 164.517 132.750 1.00 47.03  ? 656  ILE A CG1 1 
ATOM   4102 C  CG2 . ILE A 1 656 ? 167.009 166.834 132.066 1.00 47.03  ? 656  ILE A CG2 1 
ATOM   4103 C  CD1 . ILE A 1 656 ? 168.967 164.733 133.298 1.00 47.03  ? 656  ILE A CD1 1 
ATOM   4104 N  N   . SER A 1 657 ? 164.812 166.302 129.269 1.00 53.69  ? 657  SER A N   1 
ATOM   4105 C  CA  . SER A 1 657 ? 164.595 167.007 128.013 1.00 53.69  ? 657  SER A CA  1 
ATOM   4106 C  C   . SER A 1 657 ? 164.366 168.476 128.332 1.00 53.69  ? 657  SER A C   1 
ATOM   4107 O  O   . SER A 1 657 ? 164.482 168.906 129.482 1.00 53.69  ? 657  SER A O   1 
ATOM   4108 C  CB  . SER A 1 657 ? 163.427 166.400 127.231 1.00 53.69  ? 657  SER A CB  1 
ATOM   4109 O  OG  . SER A 1 657 ? 163.099 167.212 126.120 1.00 53.69  ? 657  SER A OG  1 
ATOM   4110 N  N   . VAL A 1 658 ? 164.032 169.258 127.310 1.00 56.45  ? 658  VAL A N   1 
ATOM   4111 C  CA  . VAL A 1 658 ? 163.906 170.704 127.438 1.00 56.45  ? 658  VAL A CA  1 
ATOM   4112 C  C   . VAL A 1 658 ? 162.565 171.137 126.862 1.00 56.45  ? 658  VAL A C   1 
ATOM   4113 O  O   . VAL A 1 658 ? 162.048 170.510 125.931 1.00 56.45  ? 658  VAL A O   1 
ATOM   4114 C  CB  . VAL A 1 658 ? 165.075 171.422 126.735 1.00 56.45  ? 658  VAL A CB  1 
ATOM   4115 C  CG1 . VAL A 1 658 ? 165.005 172.922 126.948 1.00 56.45  ? 658  VAL A CG1 1 
ATOM   4116 C  CG2 . VAL A 1 658 ? 166.382 170.875 127.249 1.00 56.45  ? 658  VAL A CG2 1 
ATOM   4117 N  N   . ASP A 1 659 ? 161.997 172.206 127.428 1.00 64.06  ? 659  ASP A N   1 
ATOM   4118 C  CA  . ASP A 1 659 ? 160.688 172.676 126.987 1.00 64.06  ? 659  ASP A CA  1 
ATOM   4119 C  C   . ASP A 1 659 ? 160.706 173.127 125.534 1.00 64.06  ? 659  ASP A C   1 
ATOM   4120 O  O   . ASP A 1 659 ? 159.691 173.017 124.838 1.00 64.06  ? 659  ASP A O   1 
ATOM   4121 C  CB  . ASP A 1 659 ? 160.210 173.815 127.885 1.00 64.06  ? 659  ASP A CB  1 
ATOM   4122 C  CG  . ASP A 1 659 ? 158.776 174.213 127.605 1.00 64.06  ? 659  ASP A CG  1 
ATOM   4123 O  OD1 . ASP A 1 659 ? 157.861 173.436 127.952 1.00 64.06  ? 659  ASP A OD1 1 
ATOM   4124 O  OD2 . ASP A 1 659 ? 158.563 175.303 127.035 1.00 64.06  ? 659  ASP A OD2 1 
ATOM   4125 N  N   . GLY A 1 660 ? 161.840 173.631 125.058 1.00 65.17  ? 660  GLY A N   1 
ATOM   4126 C  CA  . GLY A 1 660 ? 161.955 174.058 123.682 1.00 65.17  ? 660  GLY A CA  1 
ATOM   4127 C  C   . GLY A 1 660 ? 162.208 172.951 122.689 1.00 65.17  ? 660  GLY A C   1 
ATOM   4128 O  O   . GLY A 1 660 ? 162.476 173.228 121.517 1.00 65.17  ? 660  GLY A O   1 
ATOM   4129 N  N   . ALA A 1 661 ? 162.131 171.697 123.122 1.00 69.16  ? 661  ALA A N   1 
ATOM   4130 C  CA  . ALA A 1 661 ? 162.394 170.567 122.248 1.00 69.16  ? 661  ALA A CA  1 
ATOM   4131 C  C   . ALA A 1 661 ? 161.124 170.156 121.510 1.00 69.16  ? 661  ALA A C   1 
ATOM   4132 O  O   . ALA A 1 661 ? 160.059 170.761 121.653 1.00 69.16  ? 661  ALA A O   1 
ATOM   4133 C  CB  . ALA A 1 661 ? 162.954 169.395 123.048 1.00 69.16  ? 661  ALA A CB  1 
ATOM   4134 N  N   . VAL A 1 662 ? 161.249 169.103 120.703 1.00 72.74  ? 662  VAL A N   1 
ATOM   4135 C  CA  . VAL A 1 662 ? 160.100 168.557 119.999 1.00 72.74  ? 662  VAL A CA  1 
ATOM   4136 C  C   . VAL A 1 662 ? 159.149 167.925 121.012 1.00 72.74  ? 662  VAL A C   1 
ATOM   4137 O  O   . VAL A 1 662 ? 159.568 167.429 122.066 1.00 72.74  ? 662  VAL A O   1 
ATOM   4138 C  CB  . VAL A 1 662 ? 160.568 167.545 118.936 1.00 72.74  ? 662  VAL A CB  1 
ATOM   4139 C  CG1 . VAL A 1 662 ? 161.530 166.534 119.546 1.00 72.74  ? 662  VAL A CG1 1 
ATOM   4140 C  CG2 . VAL A 1 662 ? 159.393 166.871 118.242 1.00 72.74  ? 662  VAL A CG2 1 
ATOM   4141 N  N   . ASP A 1 663 ? 157.852 167.957 120.696 1.00 75.32  ? 663  ASP A N   1 
ATOM   4142 C  CA  . ASP A 1 663 ? 156.832 167.565 121.664 1.00 75.32  ? 663  ASP A CA  1 
ATOM   4143 C  C   . ASP A 1 663 ? 156.993 166.111 122.096 1.00 75.32  ? 663  ASP A C   1 
ATOM   4144 O  O   . ASP A 1 663 ? 156.857 165.789 123.282 1.00 75.32  ? 663  ASP A O   1 
ATOM   4145 C  CB  . ASP A 1 663 ? 155.441 167.801 121.076 1.00 75.32  ? 663  ASP A CB  1 
ATOM   4146 C  CG  . ASP A 1 663 ? 155.220 169.244 120.661 1.00 75.32  ? 663  ASP A CG  1 
ATOM   4147 O  OD1 . ASP A 1 663 ? 155.319 170.137 121.529 1.00 75.32  ? 663  ASP A OD1 1 
ATOM   4148 O  OD2 . ASP A 1 663 ? 154.948 169.486 119.466 1.00 75.32  ? 663  ASP A OD2 1 
ATOM   4149 N  N   . ILE A 1 664 ? 157.280 165.216 121.147 1.00 70.63  ? 664  ILE A N   1 
ATOM   4150 C  CA  . ILE A 1 664 ? 157.371 163.794 121.476 1.00 70.63  ? 664  ILE A CA  1 
ATOM   4151 C  C   . ILE A 1 664 ? 158.475 163.542 122.494 1.00 70.63  ? 664  ILE A C   1 
ATOM   4152 O  O   . ILE A 1 664 ? 158.293 162.765 123.441 1.00 70.63  ? 664  ILE A O   1 
ATOM   4153 C  CB  . ILE A 1 664 ? 157.573 162.957 120.196 1.00 70.63  ? 664  ILE A CB  1 
ATOM   4154 C  CG1 . ILE A 1 664 ? 157.990 161.525 120.540 1.00 70.63  ? 664  ILE A CG1 1 
ATOM   4155 C  CG2 . ILE A 1 664 ? 158.599 163.601 119.288 1.00 70.63  ? 664  ILE A CG2 1 
ATOM   4156 C  CD1 . ILE A 1 664 ? 156.927 160.737 121.277 1.00 70.63  ? 664  ILE A CD1 1 
ATOM   4157 N  N   . ALA A 1 665 ? 159.628 164.195 122.331 1.00 67.63  ? 665  ALA A N   1 
ATOM   4158 C  CA  . ALA A 1 665 ? 160.703 164.042 123.303 1.00 67.63  ? 665  ALA A CA  1 
ATOM   4159 C  C   . ALA A 1 665 ? 160.269 164.516 124.683 1.00 67.63  ? 665  ALA A C   1 
ATOM   4160 O  O   . ALA A 1 665 ? 160.594 163.883 125.693 1.00 67.63  ? 665  ALA A O   1 
ATOM   4161 C  CB  . ALA A 1 665 ? 161.944 164.800 122.840 1.00 67.63  ? 665  ALA A CB  1 
ATOM   4162 N  N   . ARG A 1 666 ? 159.536 165.629 124.747 1.00 70.55  ? 666  ARG A N   1 
ATOM   4163 C  CA  . ARG A 1 666 ? 159.049 166.113 126.034 1.00 70.55  ? 666  ARG A CA  1 
ATOM   4164 C  C   . ARG A 1 666 ? 158.099 165.113 126.678 1.00 70.55  ? 666  ARG A C   1 
ATOM   4165 O  O   . ARG A 1 666 ? 158.173 164.869 127.887 1.00 70.55  ? 666  ARG A O   1 
ATOM   4166 C  CB  . ARG A 1 666 ? 158.362 167.465 125.862 1.00 70.55  ? 666  ARG A CB  1 
ATOM   4167 C  CG  . ARG A 1 666 ? 159.311 168.619 125.626 1.00 70.55  ? 666  ARG A CG  1 
ATOM   4168 C  CD  . ARG A 1 666 ? 158.602 169.945 125.825 1.00 70.55  ? 666  ARG A CD  1 
ATOM   4169 N  NE  . ARG A 1 666 ? 157.560 170.160 124.828 1.00 70.55  ? 666  ARG A NE  1 
ATOM   4170 C  CZ  . ARG A 1 666 ? 156.260 170.100 125.081 1.00 70.55  ? 666  ARG A CZ  1 
ATOM   4171 N  NH1 . ARG A 1 666 ? 155.803 169.829 126.292 1.00 70.55  ? 666  ARG A NH1 1 
ATOM   4172 N  NH2 . ARG A 1 666 ? 155.398 170.317 124.092 1.00 70.55  ? 666  ARG A NH2 1 
ATOM   4173 N  N   . GLU A 1 667 ? 157.194 164.529 125.891 1.00 71.14  ? 667  GLU A N   1 
ATOM   4174 C  CA  . GLU A 1 667 ? 156.285 163.528 126.438 1.00 71.14  ? 667  GLU A CA  1 
ATOM   4175 C  C   . GLU A 1 667 ? 156.998 162.237 126.818 1.00 71.14  ? 667  GLU A C   1 
ATOM   4176 O  O   . GLU A 1 667 ? 156.474 161.476 127.638 1.00 71.14  ? 667  GLU A O   1 
ATOM   4177 C  CB  . GLU A 1 667 ? 155.156 163.231 125.448 1.00 71.14  ? 667  GLU A CB  1 
ATOM   4178 C  CG  . GLU A 1 667 ? 153.835 163.915 125.788 1.00 71.14  ? 667  GLU A CG  1 
ATOM   4179 C  CD  . GLU A 1 667 ? 153.811 165.388 125.433 1.00 71.14  ? 667  GLU A CD  1 
ATOM   4180 O  OE1 . GLU A 1 667 ? 153.152 166.162 126.157 1.00 71.14  ? 667  GLU A OE1 1 
ATOM   4181 O  OE2 . GLU A 1 667 ? 154.434 165.772 124.424 1.00 71.14  ? 667  GLU A OE2 1 
ATOM   4182 N  N   . ALA A 1 668 ? 158.168 161.968 126.245 1.00 63.61  ? 668  ALA A N   1 
ATOM   4183 C  CA  . ALA A 1 668 ? 158.940 160.784 126.596 1.00 63.61  ? 668  ALA A CA  1 
ATOM   4184 C  C   . ALA A 1 668 ? 160.002 161.055 127.655 1.00 63.61  ? 668  ALA A C   1 
ATOM   4185 O  O   . ALA A 1 668 ? 160.764 160.144 127.992 1.00 63.61  ? 668  ALA A O   1 
ATOM   4186 C  CB  . ALA A 1 668 ? 159.602 160.194 125.348 1.00 63.61  ? 668  ALA A CB  1 
ATOM   4187 N  N   . ALA A 1 669 ? 160.073 162.273 128.184 1.00 57.00  ? 669  ALA A N   1 
ATOM   4188 C  CA  . ALA A 1 669 ? 161.082 162.630 129.165 1.00 57.00  ? 669  ALA A CA  1 
ATOM   4189 C  C   . ALA A 1 669 ? 160.596 162.323 130.577 1.00 57.00  ? 669  ALA A C   1 
ATOM   4190 O  O   . ALA A 1 669 ? 159.509 161.782 130.788 1.00 57.00  ? 669  ALA A O   1 
ATOM   4191 C  CB  . ALA A 1 669 ? 161.455 164.103 129.034 1.00 57.00  ? 669  ALA A CB  1 
ATOM   4192 N  N   . ASP A 1 670 ? 161.416 162.680 131.564 1.00 53.23  ? 670  ASP A N   1 
ATOM   4193 C  CA  . ASP A 1 670 ? 161.065 162.465 132.960 1.00 53.23  ? 670  ASP A CA  1 
ATOM   4194 C  C   . ASP A 1 670 ? 161.316 163.733 133.764 1.00 53.23  ? 670  ASP A C   1 
ATOM   4195 O  O   . ASP A 1 670 ? 160.762 163.907 134.852 1.00 53.23  ? 670  ASP A O   1 
ATOM   4196 C  CB  . ASP A 1 670 ? 161.856 161.291 133.536 1.00 53.23  ? 670  ASP A CB  1 
ATOM   4197 C  CG  . ASP A 1 670 ? 161.035 160.450 134.490 1.00 53.23  ? 670  ASP A CG  1 
ATOM   4198 O  OD1 . ASP A 1 670 ? 159.867 160.810 134.744 1.00 53.23  ? 670  ASP A OD1 1 
ATOM   4199 O  OD2 . ASP A 1 670 ? 161.554 159.424 134.978 1.00 53.23  ? 670  ASP A OD2 1 
ATOM   4200 N  N   . ILE A 1 671 ? 162.162 164.615 133.236 1.00 49.90  ? 671  ILE A N   1 
ATOM   4201 C  CA  . ILE A 1 671 ? 162.380 165.951 133.784 1.00 49.90  ? 671  ILE A CA  1 
ATOM   4202 C  C   . ILE A 1 671 ? 162.560 166.902 132.610 1.00 49.90  ? 671  ILE A C   1 
ATOM   4203 O  O   . ILE A 1 671 ? 163.477 166.724 131.801 1.00 49.90  ? 671  ILE A O   1 
ATOM   4204 C  CB  . ILE A 1 671 ? 163.595 166.026 134.716 1.00 49.90  ? 671  ILE A CB  1 
ATOM   4205 C  CG1 . ILE A 1 671 ? 163.258 165.457 136.089 1.00 49.90  ? 671  ILE A CG1 1 
ATOM   4206 C  CG2 . ILE A 1 671 ? 164.076 167.450 134.834 1.00 49.90  ? 671  ILE A CG2 1 
ATOM   4207 C  CD1 . ILE A 1 671 ? 164.458 165.283 136.973 1.00 49.90  ? 671  ILE A CD1 1 
ATOM   4208 N  N   . ILE A 1 672 ? 161.691 167.901 132.506 1.00 49.21  ? 672  ILE A N   1 
ATOM   4209 C  CA  . ILE A 1 672 ? 161.786 168.887 131.420 1.00 49.21  ? 672  ILE A CA  1 
ATOM   4210 C  C   . ILE A 1 672 ? 162.273 170.180 132.058 1.00 49.21  ? 672  ILE A C   1 
ATOM   4211 O  O   . ILE A 1 672 ? 161.502 171.020 132.524 1.00 49.21  ? 672  ILE A O   1 
ATOM   4212 C  CB  . ILE A 1 672 ? 160.459 169.061 130.679 1.00 49.21  ? 672  ILE A CB  1 
ATOM   4213 C  CG1 . ILE A 1 672 ? 159.851 167.704 130.333 1.00 49.21  ? 672  ILE A CG1 1 
ATOM   4214 C  CG2 . ILE A 1 672 ? 160.652 169.897 129.434 1.00 49.21  ? 672  ILE A CG2 1 
ATOM   4215 C  CD1 . ILE A 1 672 ? 158.361 167.658 130.532 1.00 49.21  ? 672  ILE A CD1 1 
ATOM   4216 N  N   . LEU A 1 673 ? 163.591 170.356 132.067 1.00 49.84  ? 673  LEU A N   1 
ATOM   4217 C  CA  . LEU A 1 673 ? 164.136 171.615 132.548 1.00 49.84  ? 673  LEU A CA  1 
ATOM   4218 C  C   . LEU A 1 673 ? 163.931 172.697 131.494 1.00 49.84  ? 673  LEU A C   1 
ATOM   4219 O  O   . LEU A 1 673 ? 163.774 172.413 130.304 1.00 49.84  ? 673  LEU A O   1 
ATOM   4220 C  CB  . LEU A 1 673 ? 165.615 171.472 132.916 1.00 49.84  ? 673  LEU A CB  1 
ATOM   4221 C  CG  . LEU A 1 673 ? 166.721 171.543 131.869 1.00 49.84  ? 673  LEU A CG  1 
ATOM   4222 C  CD1 . LEU A 1 673 ? 168.041 171.790 132.558 1.00 49.84  ? 673  LEU A CD1 1 
ATOM   4223 C  CD2 . LEU A 1 673 ? 166.791 170.262 131.085 1.00 49.84  ? 673  LEU A CD2 1 
ATOM   4224 N  N   . LEU A 1 674 ? 163.908 173.951 131.946 1.00 50.58  ? 674  LEU A N   1 
ATOM   4225 C  CA  . LEU A 1 674 ? 163.460 175.032 131.076 1.00 50.58  ? 674  LEU A CA  1 
ATOM   4226 C  C   . LEU A 1 674 ? 164.448 175.304 129.948 1.00 50.58  ? 674  LEU A C   1 
ATOM   4227 O  O   . LEU A 1 674 ? 164.047 175.433 128.786 1.00 50.58  ? 674  LEU A O   1 
ATOM   4228 C  CB  . LEU A 1 674 ? 163.207 176.295 131.895 1.00 50.58  ? 674  LEU A CB  1 
ATOM   4229 C  CG  . LEU A 1 674 ? 162.126 176.127 132.965 1.00 50.58  ? 674  LEU A CG  1 
ATOM   4230 C  CD1 . LEU A 1 674 ? 161.893 177.428 133.714 1.00 50.58  ? 674  LEU A CD1 1 
ATOM   4231 C  CD2 . LEU A 1 674 ? 160.834 175.616 132.346 1.00 50.58  ? 674  LEU A CD2 1 
ATOM   4232 N  N   . GLU A 1 675 ? 165.740 175.397 130.257 1.00 53.28  ? 675  GLU A N   1 
ATOM   4233 C  CA  . GLU A 1 675 ? 166.726 175.692 129.229 1.00 53.28  ? 675  GLU A CA  1 
ATOM   4234 C  C   . GLU A 1 675 ? 167.931 174.776 129.376 1.00 53.28  ? 675  GLU A C   1 
ATOM   4235 O  O   . GLU A 1 675 ? 168.239 174.282 130.462 1.00 53.28  ? 675  GLU A O   1 
ATOM   4236 C  CB  . GLU A 1 675 ? 167.175 177.158 129.268 1.00 53.28  ? 675  GLU A CB  1 
ATOM   4237 C  CG  . GLU A 1 675 ? 167.869 177.575 130.544 1.00 53.28  ? 675  GLU A CG  1 
ATOM   4238 C  CD  . GLU A 1 675 ? 166.984 178.423 131.428 1.00 53.28  ? 675  GLU A CD  1 
ATOM   4239 O  OE1 . GLU A 1 675 ? 165.746 178.320 131.302 1.00 53.28  ? 675  GLU A OE1 1 
ATOM   4240 O  OE2 . GLU A 1 675 ? 167.526 179.202 132.238 1.00 53.28  ? 675  GLU A OE2 1 
ATOM   4241 N  N   . LYS A 1 676 ? 168.613 174.562 128.254 1.00 52.45  ? 676  LYS A N   1 
ATOM   4242 C  CA  . LYS A 1 676 ? 169.791 173.701 128.191 1.00 52.45  ? 676  LYS A CA  1 
ATOM   4243 C  C   . LYS A 1 676 ? 170.955 174.410 128.865 1.00 52.45  ? 676  LYS A C   1 
ATOM   4244 O  O   . LYS A 1 676 ? 171.500 175.381 128.336 1.00 52.45  ? 676  LYS A O   1 
ATOM   4245 C  CB  . LYS A 1 676 ? 170.117 173.355 126.744 1.00 52.45  ? 676  LYS A CB  1 
ATOM   4246 C  CG  . LYS A 1 676 ? 169.365 172.149 126.224 1.00 52.45  ? 676  LYS A CG  1 
ATOM   4247 C  CD  . LYS A 1 676 ? 170.037 171.515 125.025 1.00 52.45  ? 676  LYS A CD  1 
ATOM   4248 C  CE  . LYS A 1 676 ? 170.362 172.549 123.963 1.00 52.45  ? 676  LYS A CE  1 
ATOM   4249 N  NZ  . LYS A 1 676 ? 169.213 173.448 123.668 1.00 52.45  ? 676  LYS A NZ  1 
ATOM   4250 N  N   . SER A 1 677 ? 171.340 173.920 130.040 1.00 46.07  ? 677  SER A N   1 
ATOM   4251 C  CA  . SER A 1 677 ? 172.482 174.463 130.763 1.00 46.07  ? 677  SER A CA  1 
ATOM   4252 C  C   . SER A 1 677 ? 172.869 173.471 131.844 1.00 46.07  ? 677  SER A C   1 
ATOM   4253 O  O   . SER A 1 677 ? 172.009 173.017 132.602 1.00 46.07  ? 677  SER A O   1 
ATOM   4254 C  CB  . SER A 1 677 ? 172.158 175.826 131.379 1.00 46.07  ? 677  SER A CB  1 
ATOM   4255 O  OG  . SER A 1 677 ? 173.239 176.294 132.164 1.00 46.07  ? 677  SER A OG  1 
ATOM   4256 N  N   . LEU A 1 678 ? 174.155 173.134 131.911 1.00 42.54  ? 678  LEU A N   1 
ATOM   4257 C  CA  . LEU A 1 678 ? 174.608 172.183 132.914 1.00 42.54  ? 678  LEU A CA  1 
ATOM   4258 C  C   . LEU A 1 678 ? 174.641 172.777 134.314 1.00 42.54  ? 678  LEU A C   1 
ATOM   4259 O  O   . LEU A 1 678 ? 174.623 172.021 135.288 1.00 42.54  ? 678  LEU A O   1 
ATOM   4260 C  CB  . LEU A 1 678 ? 175.987 171.642 132.547 1.00 42.54  ? 678  LEU A CB  1 
ATOM   4261 C  CG  . LEU A 1 678 ? 175.970 170.552 131.479 1.00 42.54  ? 678  LEU A CG  1 
ATOM   4262 C  CD1 . LEU A 1 678 ? 177.378 170.084 131.183 1.00 42.54  ? 678  LEU A CD1 1 
ATOM   4263 C  CD2 . LEU A 1 678 ? 175.100 169.397 131.923 1.00 42.54  ? 678  LEU A CD2 1 
ATOM   4264 N  N   . MET A 1 679 ? 174.692 174.103 134.442 1.00 45.52  ? 679  MET A N   1 
ATOM   4265 C  CA  . MET A 1 679 ? 174.604 174.709 135.767 1.00 45.52  ? 679  MET A CA  1 
ATOM   4266 C  C   . MET A 1 679 ? 173.223 174.497 136.375 1.00 45.52  ? 679  MET A C   1 
ATOM   4267 O  O   . MET A 1 679 ? 173.101 174.164 137.562 1.00 45.52  ? 679  MET A O   1 
ATOM   4268 C  CB  . MET A 1 679 ? 174.934 176.197 135.685 1.00 45.52  ? 679  MET A CB  1 
ATOM   4269 C  CG  . MET A 1 679 ? 175.222 176.838 137.029 1.00 45.52  ? 679  MET A CG  1 
ATOM   4270 S  SD  . MET A 1 679 ? 176.566 176.019 137.910 1.00 45.52  ? 679  MET A SD  1 
ATOM   4271 C  CE  . MET A 1 679 ? 175.972 176.107 139.597 1.00 45.52  ? 679  MET A CE  1 
ATOM   4272 N  N   . VAL A 1 680 ? 172.172 174.678 135.571 1.00 39.91  ? 680  VAL A N   1 
ATOM   4273 C  CA  . VAL A 1 680 ? 170.812 174.446 136.047 1.00 39.91  ? 680  VAL A CA  1 
ATOM   4274 C  C   . VAL A 1 680 ? 170.632 172.989 136.440 1.00 39.91  ? 680  VAL A C   1 
ATOM   4275 O  O   . VAL A 1 680 ? 170.055 172.679 137.488 1.00 39.91  ? 680  VAL A O   1 
ATOM   4276 C  CB  . VAL A 1 680 ? 169.794 174.871 134.974 1.00 39.91  ? 680  VAL A CB  1 
ATOM   4277 C  CG1 . VAL A 1 680 ? 168.430 174.305 135.291 1.00 39.91  ? 680  VAL A CG1 1 
ATOM   4278 C  CG2 . VAL A 1 680 ? 169.735 176.380 134.870 1.00 39.91  ? 680  VAL A CG2 1 
ATOM   4279 N  N   . LEU A 1 681 ? 171.133 172.072 135.613 1.00 39.40  ? 681  LEU A N   1 
ATOM   4280 C  CA  . LEU A 1 681 ? 171.019 170.655 135.929 1.00 39.40  ? 681  LEU A CA  1 
ATOM   4281 C  C   . LEU A 1 681 ? 171.810 170.300 137.181 1.00 39.40  ? 681  LEU A C   1 
ATOM   4282 O  O   . LEU A 1 681 ? 171.376 169.465 137.979 1.00 39.40  ? 681  LEU A O   1 
ATOM   4283 C  CB  . LEU A 1 681 ? 171.490 169.818 134.745 1.00 39.40  ? 681  LEU A CB  1 
ATOM   4284 C  CG  . LEU A 1 681 ? 171.265 168.318 134.872 1.00 39.40  ? 681  LEU A CG  1 
ATOM   4285 C  CD1 . LEU A 1 681 ? 170.737 167.793 133.565 1.00 39.40  ? 681  LEU A CD1 1 
ATOM   4286 C  CD2 . LEU A 1 681 ? 172.548 167.610 135.250 1.00 39.40  ? 681  LEU A CD2 1 
ATOM   4287 N  N   . GLU A 1 682 ? 172.981 170.911 137.365 1.00 42.48  ? 682  GLU A N   1 
ATOM   4288 C  CA  . GLU A 1 682 ? 173.779 170.635 138.555 1.00 42.48  ? 682  GLU A CA  1 
ATOM   4289 C  C   . GLU A 1 682 ? 173.069 171.106 139.818 1.00 42.48  ? 682  GLU A C   1 
ATOM   4290 O  O   . GLU A 1 682 ? 173.036 170.387 140.826 1.00 42.48  ? 682  GLU A O   1 
ATOM   4291 C  CB  . GLU A 1 682 ? 175.149 171.297 138.426 1.00 42.48  ? 682  GLU A CB  1 
ATOM   4292 C  CG  . GLU A 1 682 ? 176.122 170.939 139.530 1.00 42.48  ? 682  GLU A CG  1 
ATOM   4293 C  CD  . GLU A 1 682 ? 176.052 171.898 140.697 1.00 42.48  ? 682  GLU A CD  1 
ATOM   4294 O  OE1 . GLU A 1 682 ? 175.418 172.962 140.549 1.00 42.48  ? 682  GLU A OE1 1 
ATOM   4295 O  OE2 . GLU A 1 682 ? 176.632 171.591 141.759 1.00 42.48  ? 682  GLU A OE2 1 
ATOM   4296 N  N   . GLU A 1 683 ? 172.494 172.308 139.784 1.00 42.33  ? 683  GLU A N   1 
ATOM   4297 C  CA  . GLU A 1 683 ? 171.734 172.781 140.936 1.00 42.33  ? 683  GLU A CA  1 
ATOM   4298 C  C   . GLU A 1 683 ? 170.511 171.906 141.178 1.00 42.33  ? 683  GLU A C   1 
ATOM   4299 O  O   . GLU A 1 683 ? 170.147 171.633 142.329 1.00 42.33  ? 683  GLU A O   1 
ATOM   4300 C  CB  . GLU A 1 683 ? 171.332 174.239 140.736 1.00 42.33  ? 683  GLU A CB  1 
ATOM   4301 C  CG  . GLU A 1 683 ? 172.499 175.204 140.825 1.00 42.33  ? 683  GLU A CG  1 
ATOM   4302 C  CD  . GLU A 1 683 ? 172.081 176.645 140.625 1.00 42.33  ? 683  GLU A CD  1 
ATOM   4303 O  OE1 . GLU A 1 683 ? 170.935 176.877 140.188 1.00 42.33  ? 683  GLU A OE1 1 
ATOM   4304 O  OE2 . GLU A 1 683 ? 172.899 177.545 140.909 1.00 42.33  ? 683  GLU A OE2 1 
ATOM   4305 N  N   . GLY A 1 684 ? 169.866 171.451 140.103 1.00 36.88  ? 684  GLY A N   1 
ATOM   4306 C  CA  . GLY A 1 684 ? 168.753 170.534 140.257 1.00 36.88  ? 684  GLY A CA  1 
ATOM   4307 C  C   . GLY A 1 684 ? 169.162 169.231 140.914 1.00 36.88  ? 684  GLY A C   1 
ATOM   4308 O  O   . GLY A 1 684 ? 168.432 168.691 141.743 1.00 36.88  ? 684  GLY A O   1 
ATOM   4309 N  N   . VAL A 1 685 ? 170.329 168.703 140.542 1.00 36.45  ? 685  VAL A N   1 
ATOM   4310 C  CA  . VAL A 1 685 ? 170.825 167.477 141.162 1.00 36.45  ? 685  VAL A CA  1 
ATOM   4311 C  C   . VAL A 1 685 ? 171.104 167.706 142.639 1.00 36.45  ? 685  VAL A C   1 
ATOM   4312 O  O   . VAL A 1 685 ? 170.783 166.864 143.488 1.00 36.45  ? 685  VAL A O   1 
ATOM   4313 C  CB  . VAL A 1 685 ? 172.079 166.969 140.428 1.00 36.45  ? 685  VAL A CB  1 
ATOM   4314 C  CG1 . VAL A 1 685 ? 172.752 165.883 141.234 1.00 36.45  ? 685  VAL A CG1 1 
ATOM   4315 C  CG2 . VAL A 1 685 ? 171.714 166.451 139.058 1.00 36.45  ? 685  VAL A CG2 1 
ATOM   4316 N  N   . ILE A 1 686 ? 171.708 168.847 142.971 1.00 34.61  ? 686  ILE A N   1 
ATOM   4317 C  CA  . ILE A 1 686 ? 171.984 169.144 144.373 1.00 34.61  ? 686  ILE A CA  1 
ATOM   4318 C  C   . ILE A 1 686 ? 170.689 169.196 145.174 1.00 34.61  ? 686  ILE A C   1 
ATOM   4319 O  O   . ILE A 1 686 ? 170.603 168.645 146.278 1.00 34.61  ? 686  ILE A O   1 
ATOM   4320 C  CB  . ILE A 1 686 ? 172.784 170.452 144.498 1.00 34.61  ? 686  ILE A CB  1 
ATOM   4321 C  CG1 . ILE A 1 686 ? 174.245 170.204 144.129 1.00 34.61  ? 686  ILE A CG1 1 
ATOM   4322 C  CG2 . ILE A 1 686 ? 172.676 171.014 145.901 1.00 34.61  ? 686  ILE A CG2 1 
ATOM   4323 C  CD1 . ILE A 1 686 ? 174.913 169.151 144.980 1.00 34.61  ? 686  ILE A CD1 1 
ATOM   4324 N  N   . GLU A 1 687 ? 169.655 169.836 144.629 1.00 33.40  ? 687  GLU A N   1 
ATOM   4325 C  CA  . GLU A 1 687 ? 168.398 169.914 145.369 1.00 33.40  ? 687  GLU A CA  1 
ATOM   4326 C  C   . GLU A 1 687 ? 167.704 168.554 145.439 1.00 33.40  ? 687  GLU A C   1 
ATOM   4327 O  O   . GLU A 1 687 ? 167.093 168.212 146.461 1.00 33.40  ? 687  GLU A O   1 
ATOM   4328 C  CB  . GLU A 1 687 ? 167.480 170.959 144.747 1.00 33.40  ? 687  GLU A CB  1 
ATOM   4329 C  CG  . GLU A 1 687 ? 166.574 171.624 145.757 1.00 33.40  ? 687  GLU A CG  1 
ATOM   4330 C  CD  . GLU A 1 687 ? 165.520 170.684 146.300 1.00 33.40  ? 687  GLU A CD  1 
ATOM   4331 O  OE1 . GLU A 1 687 ? 165.028 169.835 145.530 1.00 33.40  ? 687  GLU A OE1 1 
ATOM   4332 O  OE2 . GLU A 1 687 ? 165.198 170.776 147.501 1.00 33.40  ? 687  GLU A OE2 1 
ATOM   4333 N  N   . GLY A 1 688 ? 167.775 167.769 144.366 1.00 33.19  ? 688  GLY A N   1 
ATOM   4334 C  CA  . GLY A 1 688 ? 167.209 166.435 144.383 1.00 33.19  ? 688  GLY A CA  1 
ATOM   4335 C  C   . GLY A 1 688 ? 167.919 165.481 145.309 1.00 33.19  ? 688  GLY A C   1 
ATOM   4336 O  O   . GLY A 1 688 ? 167.335 164.460 145.685 1.00 33.19  ? 688  GLY A O   1 
ATOM   4337 N  N   . ARG A 1 689 ? 169.109 165.866 145.749 1.00 33.54  ? 689  ARG A N   1 
ATOM   4338 C  CA  . ARG A 1 689 ? 169.852 165.074 146.703 1.00 33.54  ? 689  ARG A CA  1 
ATOM   4339 C  C   . ARG A 1 689 ? 169.420 165.535 148.082 1.00 33.54  ? 689  ARG A C   1 
ATOM   4340 O  O   . ARG A 1 689 ? 169.367 164.751 149.016 1.00 33.54  ? 689  ARG A O   1 
ATOM   4341 C  CB  . ARG A 1 689 ? 171.350 165.244 146.520 1.00 33.54  ? 689  ARG A CB  1 
ATOM   4342 C  CG  . ARG A 1 689 ? 171.909 164.437 145.366 1.00 33.54  ? 689  ARG A CG  1 
ATOM   4343 C  CD  . ARG A 1 689 ? 173.420 164.475 145.357 1.00 33.54  ? 689  ARG A CD  1 
ATOM   4344 N  NE  . ARG A 1 689 ? 173.970 163.673 144.279 1.00 33.54  ? 689  ARG A NE  1 
ATOM   4345 C  CZ  . ARG A 1 689 ? 175.178 163.130 144.307 1.00 33.54  ? 689  ARG A CZ  1 
ATOM   4346 N  NH1 . ARG A 1 689 ? 175.954 163.291 145.365 1.00 33.54  ? 689  ARG A NH1 1 
ATOM   4347 N  NH2 . ARG A 1 689 ? 175.604 162.410 143.287 1.00 33.54  ? 689  ARG A NH2 1 
ATOM   4348 N  N   . ARG A 1 690 ? 169.120 166.817 148.228 1.00 31.23  ? 690  ARG A N   1 
ATOM   4349 C  CA  . ARG A 1 690 ? 168.654 167.288 149.514 1.00 31.23  ? 690  ARG A CA  1 
ATOM   4350 C  C   . ARG A 1 690 ? 167.340 166.634 149.839 1.00 31.23  ? 690  ARG A C   1 
ATOM   4351 O  O   . ARG A 1 690 ? 167.151 166.151 150.931 1.00 31.23  ? 690  ARG A O   1 
ATOM   4352 C  CB  . ARG A 1 690 ? 168.437 168.791 149.500 1.00 31.23  ? 690  ARG A CB  1 
ATOM   4353 C  CG  . ARG A 1 690 ? 169.638 169.584 149.950 1.00 31.23  ? 690  ARG A CG  1 
ATOM   4354 C  CD  . ARG A 1 690 ? 169.283 171.035 150.184 1.00 31.23  ? 690  ARG A CD  1 
ATOM   4355 N  NE  . ARG A 1 690 ? 170.455 171.759 150.645 1.00 31.23  ? 690  ARG A NE  1 
ATOM   4356 C  CZ  . ARG A 1 690 ? 171.488 172.057 149.868 1.00 31.23  ? 690  ARG A CZ  1 
ATOM   4357 N  NH1 . ARG A 1 690 ? 171.483 171.698 148.596 1.00 31.23  ? 690  ARG A NH1 1 
ATOM   4358 N  NH2 . ARG A 1 690 ? 172.526 172.714 150.361 1.00 31.23  ? 690  ARG A NH2 1 
ATOM   4359 N  N   . THR A 1 691 ? 166.443 166.568 148.870 1.00 27.89  ? 691  THR A N   1 
ATOM   4360 C  CA  . THR A 1 691 ? 165.136 165.988 149.105 1.00 27.89  ? 691  THR A CA  1 
ATOM   4361 C  C   . THR A 1 691 ? 165.246 164.543 149.491 1.00 27.89  ? 691  THR A C   1 
ATOM   4362 O  O   . THR A 1 691 ? 164.468 164.061 150.282 1.00 27.89  ? 691  THR A O   1 
ATOM   4363 C  CB  . THR A 1 691 ? 164.226 166.106 147.884 1.00 27.89  ? 691  THR A CB  1 
ATOM   4364 O  OG1 . THR A 1 691 ? 163.565 167.374 147.907 1.00 27.89  ? 691  THR A OG1 1 
ATOM   4365 C  CG2 . THR A 1 691 ? 163.189 165.021 147.914 1.00 27.89  ? 691  THR A CG2 1 
ATOM   4366 N  N   . PHE A 1 692 ? 166.193 163.837 148.904 1.00 28.21  ? 692  PHE A N   1 
ATOM   4367 C  CA  . PHE A 1 692 ? 166.401 162.434 149.246 1.00 28.21  ? 692  PHE A CA  1 
ATOM   4368 C  C   . PHE A 1 692 ? 167.015 162.297 150.632 1.00 28.21  ? 692  PHE A C   1 
ATOM   4369 O  O   . PHE A 1 692 ? 166.636 161.404 151.397 1.00 28.21  ? 692  PHE A O   1 
ATOM   4370 C  CB  . PHE A 1 692 ? 167.292 161.770 148.197 1.00 28.21  ? 692  PHE A CB  1 
ATOM   4371 C  CG  . PHE A 1 692 ? 167.090 160.287 148.066 1.00 28.21  ? 692  PHE A CG  1 
ATOM   4372 C  CD1 . PHE A 1 692 ? 166.849 159.494 149.170 1.00 28.21  ? 692  PHE A CD1 1 
ATOM   4373 C  CD2 . PHE A 1 692 ? 167.166 159.683 146.827 1.00 28.21  ? 692  PHE A CD2 1 
ATOM   4374 C  CE1 . PHE A 1 692 ? 166.672 158.136 149.041 1.00 28.21  ? 692  PHE A CE1 1 
ATOM   4375 C  CE2 . PHE A 1 692 ? 166.994 158.323 146.692 1.00 28.21  ? 692  PHE A CE2 1 
ATOM   4376 C  CZ  . PHE A 1 692 ? 166.744 157.549 147.799 1.00 28.21  ? 692  PHE A CZ  1 
ATOM   4377 N  N   . ALA A 1 693 ? 167.967 163.167 150.973 1.00 24.75  ? 693  ALA A N   1 
ATOM   4378 C  CA  . ALA A 1 693 ? 168.581 163.085 152.291 1.00 24.75  ? 693  ALA A CA  1 
ATOM   4379 C  C   . ALA A 1 693 ? 167.545 163.265 153.388 1.00 24.75  ? 693  ALA A C   1 
ATOM   4380 O  O   . ALA A 1 693 ? 167.540 162.515 154.365 1.00 24.75  ? 693  ALA A O   1 
ATOM   4381 C  CB  . ALA A 1 693 ? 169.689 164.125 152.424 1.00 24.75  ? 693  ALA A CB  1 
ATOM   4382 N  N   . ASN A 1 694 ? 166.643 164.236 153.235 1.00 23.59  ? 694  ASN A N   1 
ATOM   4383 C  CA  . ASN A 1 694 ? 165.592 164.439 154.228 1.00 23.59  ? 694  ASN A CA  1 
ATOM   4384 C  C   . ASN A 1 694 ? 164.652 163.245 154.294 1.00 23.59  ? 694  ASN A C   1 
ATOM   4385 O  O   . ASN A 1 694 ? 164.307 162.770 155.386 1.00 23.59  ? 694  ASN A O   1 
ATOM   4386 C  CB  . ASN A 1 694 ? 164.807 165.705 153.901 1.00 23.59  ? 694  ASN A CB  1 
ATOM   4387 C  CG  . ASN A 1 694 ? 165.489 166.951 154.391 1.00 23.59  ? 694  ASN A CG  1 
ATOM   4388 O  OD1 . ASN A 1 694 ? 166.269 166.909 155.337 1.00 23.59  ? 694  ASN A OD1 1 
ATOM   4389 N  ND2 . ASN A 1 694 ? 165.210 168.073 153.743 1.00 23.59  ? 694  ASN A ND2 1 
ATOM   4390 N  N   . MET A 1 695 ? 164.218 162.750 153.134 1.00 23.69  ? 695  MET A N   1 
ATOM   4391 C  CA  . MET A 1 695 ? 163.245 161.664 153.113 1.00 23.69  ? 695  MET A CA  1 
ATOM   4392 C  C   . MET A 1 695 ? 163.815 160.394 153.730 1.00 23.69  ? 695  MET A C   1 
ATOM   4393 O  O   . MET A 1 695 ? 163.092 159.631 154.379 1.00 23.69  ? 695  MET A O   1 
ATOM   4394 C  CB  . MET A 1 695 ? 162.783 161.410 151.681 1.00 23.69  ? 695  MET A CB  1 
ATOM   4395 C  CG  . MET A 1 695 ? 161.939 160.180 151.517 1.00 23.69  ? 695  MET A CG  1 
ATOM   4396 S  SD  . MET A 1 695 ? 162.851 158.837 150.755 1.00 23.69  ? 695  MET A SD  1 
ATOM   4397 C  CE  . MET A 1 695 ? 162.700 159.296 149.035 1.00 23.69  ? 695  MET A CE  1 
ATOM   4398 N  N   . LEU A 1 696 ? 165.107 160.145 153.530 1.00 24.25  ? 696  LEU A N   1 
ATOM   4399 C  CA  . LEU A 1 696 ? 165.753 158.983 154.129 1.00 24.25  ? 696  LEU A CA  1 
ATOM   4400 C  C   . LEU A 1 696 ? 166.094 159.213 155.595 1.00 24.25  ? 696  LEU A C   1 
ATOM   4401 O  O   . LEU A 1 696 ? 166.058 158.271 156.398 1.00 24.25  ? 696  LEU A O   1 
ATOM   4402 C  CB  . LEU A 1 696 ? 167.005 158.637 153.327 1.00 24.25  ? 696  LEU A CB  1 
ATOM   4403 C  CG  . LEU A 1 696 ? 167.878 157.469 153.753 1.00 24.25  ? 696  LEU A CG  1 
ATOM   4404 C  CD1 . LEU A 1 696 ? 168.307 156.700 152.525 1.00 24.25  ? 696  LEU A CD1 1 
ATOM   4405 C  CD2 . LEU A 1 696 ? 169.087 157.999 154.489 1.00 24.25  ? 696  LEU A CD2 1 
ATOM   4406 N  N   . LYS A 1 697 ? 166.425 160.449 155.956 1.00 22.49  ? 697  LYS A N   1 
ATOM   4407 C  CA  . LYS A 1 697 ? 166.761 160.774 157.332 1.00 22.49  ? 697  LYS A CA  1 
ATOM   4408 C  C   . LYS A 1 697 ? 165.560 160.594 158.242 1.00 22.49  ? 697  LYS A C   1 
ATOM   4409 O  O   . LYS A 1 697 ? 165.687 160.068 159.353 1.00 22.49  ? 697  LYS A O   1 
ATOM   4410 C  CB  . LYS A 1 697 ? 167.281 162.207 157.384 1.00 22.49  ? 697  LYS A CB  1 
ATOM   4411 C  CG  . LYS A 1 697 ? 167.960 162.615 158.656 1.00 22.49  ? 697  LYS A CG  1 
ATOM   4412 C  CD  . LYS A 1 697 ? 168.705 163.918 158.436 1.00 22.49  ? 697  LYS A CD  1 
ATOM   4413 C  CE  . LYS A 1 697 ? 167.747 165.041 158.107 1.00 22.49  ? 697  LYS A CE  1 
ATOM   4414 N  NZ  . LYS A 1 697 ? 168.471 166.322 157.937 1.00 22.49  ? 697  LYS A NZ  1 
ATOM   4415 N  N   . TYR A 1 698 ? 164.382 161.016 157.783 1.00 25.43  ? 698  TYR A N   1 
ATOM   4416 C  CA  . TYR A 1 698 ? 163.172 160.794 158.568 1.00 25.43  ? 698  TYR A CA  1 
ATOM   4417 C  C   . TYR A 1 698 ? 162.923 159.307 158.782 1.00 25.43  ? 698  TYR A C   1 
ATOM   4418 O  O   . TYR A 1 698 ? 162.563 158.881 159.888 1.00 25.43  ? 698  TYR A O   1 
ATOM   4419 C  CB  . TYR A 1 698 ? 161.974 161.438 157.879 1.00 25.43  ? 698  TYR A CB  1 
ATOM   4420 C  CG  . TYR A 1 698 ? 160.667 160.761 158.199 1.00 25.43  ? 698  TYR A CG  1 
ATOM   4421 C  CD1 . TYR A 1 698 ? 160.063 160.924 159.435 1.00 25.43  ? 698  TYR A CD1 1 
ATOM   4422 C  CD2 . TYR A 1 698 ? 160.041 159.950 157.269 1.00 25.43  ? 698  TYR A CD2 1 
ATOM   4423 C  CE1 . TYR A 1 698 ? 158.867 160.307 159.732 1.00 25.43  ? 698  TYR A CE1 1 
ATOM   4424 C  CE2 . TYR A 1 698 ? 158.847 159.326 157.560 1.00 25.43  ? 698  TYR A CE2 1 
ATOM   4425 C  CZ  . TYR A 1 698 ? 158.265 159.508 158.792 1.00 25.43  ? 698  TYR A CZ  1 
ATOM   4426 O  OH  . TYR A 1 698 ? 157.076 158.889 159.084 1.00 25.43  ? 698  TYR A OH  1 
ATOM   4427 N  N   . ILE A 1 699 ? 163.104 158.506 157.731 1.00 23.92  ? 699  ILE A N   1 
ATOM   4428 C  CA  . ILE A 1 699 ? 162.903 157.063 157.832 1.00 23.92  ? 699  ILE A CA  1 
ATOM   4429 C  C   . ILE A 1 699 ? 163.835 156.472 158.877 1.00 23.92  ? 699  ILE A C   1 
ATOM   4430 O  O   . ILE A 1 699 ? 163.413 155.706 159.750 1.00 23.92  ? 699  ILE A O   1 
ATOM   4431 C  CB  . ILE A 1 699 ? 163.114 156.397 156.463 1.00 23.92  ? 699  ILE A CB  1 
ATOM   4432 C  CG1 . ILE A 1 699 ? 161.954 156.719 155.527 1.00 23.92  ? 699  ILE A CG1 1 
ATOM   4433 C  CG2 . ILE A 1 699 ? 163.278 154.904 156.621 1.00 23.92  ? 699  ILE A CG2 1 
ATOM   4434 C  CD1 . ILE A 1 699 ? 162.023 155.981 154.220 1.00 23.92  ? 699  ILE A CD1 1 
ATOM   4435 N  N   . LYS A 1 700 ? 165.121 156.819 158.801 1.00 26.54  ? 700  LYS A N   1 
ATOM   4436 C  CA  . LYS A 1 700 ? 166.078 156.270 159.756 1.00 26.54  ? 700  LYS A CA  1 
ATOM   4437 C  C   . LYS A 1 700 ? 165.762 156.699 161.183 1.00 26.54  ? 700  LYS A C   1 
ATOM   4438 O  O   . LYS A 1 700 ? 165.803 155.869 162.100 1.00 26.54  ? 700  LYS A O   1 
ATOM   4439 C  CB  . LYS A 1 700 ? 167.497 156.680 159.375 1.00 26.54  ? 700  LYS A CB  1 
ATOM   4440 C  CG  . LYS A 1 700 ? 168.198 155.668 158.493 1.00 26.54  ? 700  LYS A CG  1 
ATOM   4441 C  CD  . LYS A 1 700 ? 169.261 156.311 157.625 1.00 26.54  ? 700  LYS A CD  1 
ATOM   4442 C  CE  . LYS A 1 700 ? 170.406 156.862 158.451 1.00 26.54  ? 700  LYS A CE  1 
ATOM   4443 N  NZ  . LYS A 1 700 ? 171.708 156.700 157.748 1.00 26.54  ? 700  LYS A NZ  1 
ATOM   4444 N  N   . MET A 1 701 ? 165.423 157.974 161.387 1.00 23.65  ? 701  MET A N   1 
ATOM   4445 C  CA  . MET A 1 701 ? 165.106 158.454 162.728 1.00 23.65  ? 701  MET A CA  1 
ATOM   4446 C  C   . MET A 1 701 ? 163.923 157.702 163.314 1.00 23.65  ? 701  MET A C   1 
ATOM   4447 O  O   . MET A 1 701 ? 163.989 157.193 164.442 1.00 23.65  ? 701  MET A O   1 
ATOM   4448 C  CB  . MET A 1 701 ? 164.780 159.940 162.685 1.00 23.65  ? 701  MET A CB  1 
ATOM   4449 C  CG  . MET A 1 701 ? 165.947 160.872 162.660 1.00 23.65  ? 701  MET A CG  1 
ATOM   4450 S  SD  . MET A 1 701 ? 165.259 162.527 162.649 1.00 23.65  ? 701  MET A SD  1 
ATOM   4451 C  CE  . MET A 1 701 ? 166.541 163.401 161.791 1.00 23.65  ? 701  MET A CE  1 
ATOM   4452 N  N   . THR A 1 702 ? 162.820 157.644 162.565 1.00 24.05  ? 702  THR A N   1 
ATOM   4453 C  CA  . THR A 1 702 ? 161.616 157.010 163.082 1.00 24.05  ? 702  THR A CA  1 
ATOM   4454 C  C   . THR A 1 702 ? 161.834 155.524 163.315 1.00 24.05  ? 702  THR A C   1 
ATOM   4455 O  O   . THR A 1 702 ? 161.382 154.979 164.327 1.00 24.05  ? 702  THR A O   1 
ATOM   4456 C  CB  . THR A 1 702 ? 160.450 157.239 162.129 1.00 24.05  ? 702  THR A CB  1 
ATOM   4457 O  OG1 . THR A 1 702 ? 160.334 158.638 161.853 1.00 24.05  ? 702  THR A OG1 1 
ATOM   4458 C  CG2 . THR A 1 702 ? 159.163 156.762 162.757 1.00 24.05  ? 702  THR A CG2 1 
ATOM   4459 N  N   . ALA A 1 703 ? 162.533 154.851 162.399 1.00 24.24  ? 703  ALA A N   1 
ATOM   4460 C  CA  . ALA A 1 703 ? 162.794 153.431 162.583 1.00 24.24  ? 703  ALA A CA  1 
ATOM   4461 C  C   . ALA A 1 703 ? 163.610 153.178 163.841 1.00 24.24  ? 703  ALA A C   1 
ATOM   4462 O  O   . ALA A 1 703 ? 163.277 152.290 164.635 1.00 24.24  ? 703  ALA A O   1 
ATOM   4463 C  CB  . ALA A 1 703 ? 163.507 152.871 161.356 1.00 24.24  ? 703  ALA A CB  1 
ATOM   4464 N  N   . SER A 1 704 ? 164.671 153.961 164.056 1.00 25.00  ? 704  SER A N   1 
ATOM   4465 C  CA  . SER A 1 704 ? 165.504 153.743 165.234 1.00 25.00  ? 704  SER A CA  1 
ATOM   4466 C  C   . SER A 1 704 ? 164.734 154.008 166.520 1.00 25.00  ? 704  SER A C   1 
ATOM   4467 O  O   . SER A 1 704 ? 164.810 153.217 167.469 1.00 25.00  ? 704  SER A O   1 
ATOM   4468 C  CB  . SER A 1 704 ? 166.748 154.620 165.170 1.00 25.00  ? 704  SER A CB  1 
ATOM   4469 O  OG  . SER A 1 704 ? 166.426 155.972 165.427 1.00 25.00  ? 704  SER A OG  1 
ATOM   4470 N  N   . SER A 1 705 ? 163.982 155.110 166.577 1.00 22.53  ? 705  SER A N   1 
ATOM   4471 C  CA  . SER A 1 705 ? 163.248 155.418 167.800 1.00 22.53  ? 705  SER A CA  1 
ATOM   4472 C  C   . SER A 1 705 ? 162.176 154.371 168.088 1.00 22.53  ? 705  SER A C   1 
ATOM   4473 O  O   . SER A 1 705 ? 162.013 153.937 169.238 1.00 22.53  ? 705  SER A O   1 
ATOM   4474 C  CB  . SER A 1 705 ? 162.631 156.808 167.698 1.00 22.53  ? 705  SER A CB  1 
ATOM   4475 O  OG  . SER A 1 705 ? 163.618 157.808 167.867 1.00 22.53  ? 705  SER A OG  1 
ATOM   4476 N  N   . ASN A 1 706 ? 161.436 153.952 167.058 1.00 25.48  ? 706  ASN A N   1 
ATOM   4477 C  CA  . ASN A 1 706 ? 160.407 152.942 167.259 1.00 25.48  ? 706  ASN A CA  1 
ATOM   4478 C  C   . ASN A 1 706 ? 161.013 151.626 167.720 1.00 25.48  ? 706  ASN A C   1 
ATOM   4479 O  O   . ASN A 1 706 ? 160.466 150.962 168.608 1.00 25.48  ? 706  ASN A O   1 
ATOM   4480 C  CB  . ASN A 1 706 ? 159.608 152.744 165.974 1.00 25.48  ? 706  ASN A CB  1 
ATOM   4481 C  CG  . ASN A 1 706 ? 158.723 153.927 165.653 1.00 25.48  ? 706  ASN A CG  1 
ATOM   4482 O  OD1 . ASN A 1 706 ? 158.859 154.995 166.242 1.00 25.48  ? 706  ASN A OD1 1 
ATOM   4483 N  ND2 . ASN A 1 706 ? 157.810 153.741 164.711 1.00 25.48  ? 706  ASN A ND2 1 
ATOM   4484 N  N   . PHE A 1 707 ? 162.144 151.228 167.132 1.00 27.09  ? 707  PHE A N   1 
ATOM   4485 C  CA  . PHE A 1 707 ? 162.778 149.995 167.578 1.00 27.09  ? 707  PHE A CA  1 
ATOM   4486 C  C   . PHE A 1 707 ? 163.266 150.103 169.011 1.00 27.09  ? 707  PHE A C   1 
ATOM   4487 O  O   . PHE A 1 707 ? 163.200 149.124 169.756 1.00 27.09  ? 707  PHE A O   1 
ATOM   4488 C  CB  . PHE A 1 707 ? 163.939 149.612 166.672 1.00 27.09  ? 707  PHE A CB  1 
ATOM   4489 C  CG  . PHE A 1 707 ? 164.634 148.360 167.105 1.00 27.09  ? 707  PHE A CG  1 
ATOM   4490 C  CD1 . PHE A 1 707 ? 163.948 147.165 167.167 1.00 27.09  ? 707  PHE A CD1 1 
ATOM   4491 C  CD2 . PHE A 1 707 ? 165.964 148.380 167.470 1.00 27.09  ? 707  PHE A CD2 1 
ATOM   4492 C  CE1 . PHE A 1 707 ? 164.580 146.013 167.571 1.00 27.09  ? 707  PHE A CE1 1 
ATOM   4493 C  CE2 . PHE A 1 707 ? 166.600 147.226 167.873 1.00 27.09  ? 707  PHE A CE2 1 
ATOM   4494 C  CZ  . PHE A 1 707 ? 165.907 146.043 167.924 1.00 27.09  ? 707  PHE A CZ  1 
ATOM   4495 N  N   . GLY A 1 708 ? 163.772 151.268 169.414 1.00 27.00  ? 708  GLY A N   1 
ATOM   4496 C  CA  . GLY A 1 708 ? 164.154 151.440 170.807 1.00 27.00  ? 708  GLY A CA  1 
ATOM   4497 C  C   . GLY A 1 708 ? 162.982 151.268 171.754 1.00 27.00  ? 708  GLY A C   1 
ATOM   4498 O  O   . GLY A 1 708 ? 163.082 150.559 172.762 1.00 27.00  ? 708  GLY A O   1 
ATOM   4499 N  N   . ASN A 1 709 ? 161.850 151.900 171.434 1.00 27.70  ? 709  ASN A N   1 
ATOM   4500 C  CA  . ASN A 1 709 ? 160.665 151.757 172.279 1.00 27.70  ? 709  ASN A CA  1 
ATOM   4501 C  C   . ASN A 1 709 ? 160.201 150.306 172.341 1.00 27.70  ? 709  ASN A C   1 
ATOM   4502 O  O   . ASN A 1 709 ? 159.841 149.802 173.413 1.00 27.70  ? 709  ASN A O   1 
ATOM   4503 C  CB  . ASN A 1 709 ? 159.537 152.650 171.765 1.00 27.70  ? 709  ASN A CB  1 
ATOM   4504 C  CG  . ASN A 1 709 ? 159.799 154.117 172.008 1.00 27.70  ? 709  ASN A CG  1 
ATOM   4505 O  OD1 . ASN A 1 709 ? 160.894 154.510 172.409 1.00 27.70  ? 709  ASN A OD1 1 
ATOM   4506 N  ND2 . ASN A 1 709 ? 158.788 154.940 171.770 1.00 27.70  ? 709  ASN A ND2 1 
ATOM   4507 N  N   . VAL A 1 710 ? 160.206 149.619 171.200 1.00 28.88  ? 710  VAL A N   1 
ATOM   4508 C  CA  . VAL A 1 710 ? 159.750 148.233 171.157 1.00 28.88  ? 710  VAL A CA  1 
ATOM   4509 C  C   . VAL A 1 710 ? 160.687 147.324 171.944 1.00 28.88  ? 710  VAL A C   1 
ATOM   4510 O  O   . VAL A 1 710 ? 160.242 146.429 172.676 1.00 28.88  ? 710  VAL A O   1 
ATOM   4511 C  CB  . VAL A 1 710 ? 159.607 147.783 169.695 1.00 28.88  ? 710  VAL A CB  1 
ATOM   4512 C  CG1 . VAL A 1 710 ? 159.679 146.293 169.600 1.00 28.88  ? 710  VAL A CG1 1 
ATOM   4513 C  CG2 . VAL A 1 710 ? 158.296 148.284 169.140 1.00 28.88  ? 710  VAL A CG2 1 
ATOM   4514 N  N   . PHE A 1 711 ? 161.997 147.536 171.812 1.00 31.92  ? 711  PHE A N   1 
ATOM   4515 C  CA  . PHE A 1 711 ? 162.958 146.771 172.598 1.00 31.92  ? 711  PHE A CA  1 
ATOM   4516 C  C   . PHE A 1 711 ? 162.735 146.985 174.085 1.00 31.92  ? 711  PHE A C   1 
ATOM   4517 O  O   . PHE A 1 711 ? 162.770 146.031 174.873 1.00 31.92  ? 711  PHE A O   1 
ATOM   4518 C  CB  . PHE A 1 711 ? 164.377 147.172 172.205 1.00 31.92  ? 711  PHE A CB  1 
ATOM   4519 C  CG  . PHE A 1 711 ? 165.436 146.245 172.714 1.00 31.92  ? 711  PHE A CG  1 
ATOM   4520 C  CD1 . PHE A 1 711 ? 165.585 144.981 172.178 1.00 31.92  ? 711  PHE A CD1 1 
ATOM   4521 C  CD2 . PHE A 1 711 ? 166.294 146.646 173.721 1.00 31.92  ? 711  PHE A CD2 1 
ATOM   4522 C  CE1 . PHE A 1 711 ? 166.564 144.129 172.644 1.00 31.92  ? 711  PHE A CE1 1 
ATOM   4523 C  CE2 . PHE A 1 711 ? 167.274 145.800 174.191 1.00 31.92  ? 711  PHE A CE2 1 
ATOM   4524 C  CZ  . PHE A 1 711 ? 167.409 144.540 173.652 1.00 31.92  ? 711  PHE A CZ  1 
ATOM   4525 N  N   . SER A 1 712 ? 162.493 148.233 174.489 1.00 31.60  ? 712  SER A N   1 
ATOM   4526 C  CA  . SER A 1 712 ? 162.232 148.502 175.897 1.00 31.60  ? 712  SER A CA  1 
ATOM   4527 C  C   . SER A 1 712 ? 160.978 147.787 176.373 1.00 31.60  ? 712  SER A C   1 
ATOM   4528 O  O   . SER A 1 712 ? 160.943 147.261 177.490 1.00 31.60  ? 712  SER A O   1 
ATOM   4529 C  CB  . SER A 1 712 ? 162.106 149.999 176.136 1.00 31.60  ? 712  SER A CB  1 
ATOM   4530 O  OG  . SER A 1 712 ? 162.167 150.258 177.521 1.00 31.60  ? 712  SER A OG  1 
ATOM   4531 N  N   . VAL A 1 713 ? 159.932 147.768 175.548 1.00 31.83  ? 713  VAL A N   1 
ATOM   4532 C  CA  . VAL A 1 713 ? 158.727 147.027 175.914 1.00 31.83  ? 713  VAL A CA  1 
ATOM   4533 C  C   . VAL A 1 713 ? 159.054 145.550 176.087 1.00 31.83  ? 713  VAL A C   1 
ATOM   4534 O  O   . VAL A 1 713 ? 158.553 144.887 177.003 1.00 31.83  ? 713  VAL A O   1 
ATOM   4535 C  CB  . VAL A 1 713 ? 157.619 147.242 174.868 1.00 31.83  ? 713  VAL A CB  1 
ATOM   4536 C  CG1 . VAL A 1 713 ? 156.535 146.191 175.018 1.00 31.83  ? 713  VAL A CG1 1 
ATOM   4537 C  CG2 . VAL A 1 713 ? 157.030 148.629 175.007 1.00 31.83  ? 713  VAL A CG2 1 
ATOM   4538 N  N   . LEU A 1 714 ? 159.915 145.015 175.219 1.00 36.70  ? 714  LEU A N   1 
ATOM   4539 C  CA  . LEU A 1 714 ? 160.222 143.588 175.280 1.00 36.70  ? 714  LEU A CA  1 
ATOM   4540 C  C   . LEU A 1 714 ? 160.987 143.232 176.549 1.00 36.70  ? 714  LEU A C   1 
ATOM   4541 O  O   . LEU A 1 714 ? 160.629 142.275 177.245 1.00 36.70  ? 714  LEU A O   1 
ATOM   4542 C  CB  . LEU A 1 714 ? 161.000 143.158 174.032 1.00 36.70  ? 714  LEU A CB  1 
ATOM   4543 C  CG  . LEU A 1 714 ? 161.767 141.828 174.005 1.00 36.70  ? 714  LEU A CG  1 
ATOM   4544 C  CD1 . LEU A 1 714 ? 161.889 141.362 172.576 1.00 36.70  ? 714  LEU A CD1 1 
ATOM   4545 C  CD2 . LEU A 1 714 ? 163.166 141.924 174.595 1.00 36.70  ? 714  LEU A CD2 1 
ATOM   4546 N  N   . VAL A 1 715 ? 162.049 143.978 176.865 1.00 36.78  ? 715  VAL A N   1 
ATOM   4547 C  CA  . VAL A 1 715 ? 162.899 143.589 177.989 1.00 36.78  ? 715  VAL A CA  1 
ATOM   4548 C  C   . VAL A 1 715 ? 162.154 143.720 179.314 1.00 36.78  ? 715  VAL A C   1 
ATOM   4549 O  O   . VAL A 1 715 ? 162.396 142.951 180.251 1.00 36.78  ? 715  VAL A O   1 
ATOM   4550 C  CB  . VAL A 1 715 ? 164.215 144.391 177.990 1.00 36.78  ? 715  VAL A CB  1 
ATOM   4551 C  CG1 . VAL A 1 715 ? 164.799 144.461 176.598 1.00 36.78  ? 715  VAL A CG1 1 
ATOM   4552 C  CG2 . VAL A 1 715 ? 163.994 145.787 178.526 1.00 36.78  ? 715  VAL A CG2 1 
ATOM   4553 N  N   . ALA A 1 716 ? 161.241 144.681 179.420 1.00 40.00  ? 716  ALA A N   1 
ATOM   4554 C  CA  . ALA A 1 716 ? 160.479 144.882 180.644 1.00 40.00  ? 716  ALA A CA  1 
ATOM   4555 C  C   . ALA A 1 716 ? 159.104 144.233 180.598 1.00 40.00  ? 716  ALA A C   1 
ATOM   4556 O  O   . ALA A 1 716 ? 158.290 144.478 181.492 1.00 40.00  ? 716  ALA A O   1 
ATOM   4557 C  CB  . ALA A 1 716 ? 160.331 146.376 180.937 1.00 40.00  ? 716  ALA A CB  1 
ATOM   4558 N  N   . SER A 1 717 ? 158.824 143.427 179.573 1.00 45.88  ? 717  SER A N   1 
ATOM   4559 C  CA  . SER A 1 717 ? 157.527 142.766 179.482 1.00 45.88  ? 717  SER A CA  1 
ATOM   4560 C  C   . SER A 1 717 ? 157.331 141.764 180.611 1.00 45.88  ? 717  SER A C   1 
ATOM   4561 O  O   . SER A 1 717 ? 156.234 141.656 181.171 1.00 45.88  ? 717  SER A O   1 
ATOM   4562 C  CB  . SER A 1 717 ? 157.390 142.074 178.128 1.00 45.88  ? 717  SER A CB  1 
ATOM   4563 O  OG  . SER A 1 717 ? 158.439 141.143 177.930 1.00 45.88  ? 717  SER A OG  1 
ATOM   4564 N  N   . ALA A 1 718 ? 158.380 141.015 180.953 1.00 49.66  ? 718  ALA A N   1 
ATOM   4565 C  CA  . ALA A 1 718 ? 158.239 139.932 181.921 1.00 49.66  ? 718  ALA A CA  1 
ATOM   4566 C  C   . ALA A 1 718 ? 157.987 140.465 183.326 1.00 49.66  ? 718  ALA A C   1 
ATOM   4567 O  O   . ALA A 1 718 ? 157.113 139.967 184.045 1.00 49.66  ? 718  ALA A O   1 
ATOM   4568 C  CB  . ALA A 1 718 ? 159.487 139.050 181.897 1.00 49.66  ? 718  ALA A CB  1 
ATOM   4569 N  N   . PHE A 1 719 ? 158.744 141.483 183.734 1.00 50.09  ? 719  PHE A N   1 
ATOM   4570 C  CA  . PHE A 1 719 ? 158.749 141.886 185.136 1.00 50.09  ? 719  PHE A CA  1 
ATOM   4571 C  C   . PHE A 1 719 ? 157.501 142.679 185.503 1.00 50.09  ? 719  PHE A C   1 
ATOM   4572 O  O   . PHE A 1 719 ? 156.998 142.565 186.626 1.00 50.09  ? 719  PHE A O   1 
ATOM   4573 C  CB  . PHE A 1 719 ? 160.014 142.684 185.461 1.00 50.09  ? 719  PHE A CB  1 
ATOM   4574 C  CG  . PHE A 1 719 ? 161.301 141.972 185.114 1.00 50.09  ? 719  PHE A CG  1 
ATOM   4575 C  CD1 . PHE A 1 719 ? 162.220 141.679 186.107 1.00 50.09  ? 719  PHE A CD1 1 
ATOM   4576 C  CD2 . PHE A 1 719 ? 161.615 141.634 183.806 1.00 50.09  ? 719  PHE A CD2 1 
ATOM   4577 C  CE1 . PHE A 1 719 ? 163.404 141.035 185.809 1.00 50.09  ? 719  PHE A CE1 1 
ATOM   4578 C  CE2 . PHE A 1 719 ? 162.796 140.991 183.504 1.00 50.09  ? 719  PHE A CE2 1 
ATOM   4579 C  CZ  . PHE A 1 719 ? 163.693 140.693 184.505 1.00 50.09  ? 719  PHE A CZ  1 
ATOM   4580 N  N   . LEU A 1 720 ? 156.991 143.481 184.590 1.00 43.79  ? 720  LEU A N   1 
ATOM   4581 C  CA  . LEU A 1 720 ? 155.810 144.272 184.906 1.00 43.79  ? 720  LEU A CA  1 
ATOM   4582 C  C   . LEU A 1 720 ? 154.560 143.404 184.820 1.00 43.79  ? 720  LEU A C   1 
ATOM   4583 O  O   . LEU A 1 720 ? 154.300 142.807 183.772 1.00 43.79  ? 720  LEU A O   1 
ATOM   4584 C  CB  . LEU A 1 720 ? 155.689 145.461 183.963 1.00 43.79  ? 720  LEU A CB  1 
ATOM   4585 C  CG  . LEU A 1 720 ? 156.905 146.382 183.924 1.00 43.79  ? 720  LEU A CG  1 
ATOM   4586 C  CD1 . LEU A 1 720 ? 156.890 147.232 182.675 1.00 43.79  ? 720  LEU A CD1 1 
ATOM   4587 C  CD2 . LEU A 1 720 ? 156.941 147.255 185.160 1.00 43.79  ? 720  LEU A CD2 1 
ATOM   4588 N  N   . PRO A 1 721 ? 153.771 143.307 185.894 1.00 43.85  ? 721  PRO A N   1 
ATOM   4589 C  CA  . PRO A 1 721 ? 152.514 142.548 185.812 1.00 43.85  ? 721  PRO A CA  1 
ATOM   4590 C  C   . PRO A 1 721 ? 151.519 143.137 184.832 1.00 43.85  ? 721  PRO A C   1 
ATOM   4591 O  O   . PRO A 1 721 ? 150.620 142.419 184.379 1.00 43.85  ? 721  PRO A O   1 
ATOM   4592 C  CB  . PRO A 1 721 ? 151.978 142.603 187.247 1.00 43.85  ? 721  PRO A CB  1 
ATOM   4593 C  CG  . PRO A 1 721 ? 152.588 143.833 187.823 1.00 43.85  ? 721  PRO A CG  1 
ATOM   4594 C  CD  . PRO A 1 721 ? 153.957 143.926 187.216 1.00 43.85  ? 721  PRO A CD  1 
ATOM   4595 N  N   . PHE A 1 722 ? 151.649 144.414 184.495 1.00 41.22  ? 722  PHE A N   1 
ATOM   4596 C  CA  . PHE A 1 722 ? 150.756 145.103 183.580 1.00 41.22  ? 722  PHE A CA  1 
ATOM   4597 C  C   . PHE A 1 722 ? 151.526 145.567 182.352 1.00 41.22  ? 722  PHE A C   1 
ATOM   4598 O  O   . PHE A 1 722 ? 152.752 145.452 182.279 1.00 41.22  ? 722  PHE A O   1 
ATOM   4599 C  CB  . PHE A 1 722 ? 150.095 146.299 184.267 1.00 41.22  ? 722  PHE A CB  1 
ATOM   4600 C  CG  . PHE A 1 722 ? 151.058 147.171 185.019 1.00 41.22  ? 722  PHE A CG  1 
ATOM   4601 C  CD1 . PHE A 1 722 ? 151.349 146.919 186.346 1.00 41.22  ? 722  PHE A CD1 1 
ATOM   4602 C  CD2 . PHE A 1 722 ? 151.671 148.242 184.399 1.00 41.22  ? 722  PHE A CD2 1 
ATOM   4603 C  CE1 . PHE A 1 722 ? 152.234 147.717 187.037 1.00 41.22  ? 722  PHE A CE1 1 
ATOM   4604 C  CE2 . PHE A 1 722 ? 152.554 149.044 185.088 1.00 41.22  ? 722  PHE A CE2 1 
ATOM   4605 C  CZ  . PHE A 1 722 ? 152.835 148.781 186.406 1.00 41.22  ? 722  PHE A CZ  1 
ATOM   4606 N  N   . LEU A 1 723 ? 150.789 146.090 181.381 1.00 37.87  ? 723  LEU A N   1 
ATOM   4607 C  CA  . LEU A 1 723 ? 151.419 146.605 180.177 1.00 37.87  ? 723  LEU A CA  1 
ATOM   4608 C  C   . LEU A 1 723 ? 152.279 147.820 180.517 1.00 37.87  ? 723  LEU A C   1 
ATOM   4609 O  O   . LEU A 1 723 ? 151.846 148.693 181.277 1.00 37.87  ? 723  LEU A O   1 
ATOM   4610 C  CB  . LEU A 1 723 ? 150.365 146.985 179.139 1.00 37.87  ? 723  LEU A CB  1 
ATOM   4611 C  CG  . LEU A 1 723 ? 150.014 145.917 178.108 1.00 37.87  ? 723  LEU A CG  1 
ATOM   4612 C  CD1 . LEU A 1 723 ? 148.607 146.118 177.607 1.00 37.87  ? 723  LEU A CD1 1 
ATOM   4613 C  CD2 . LEU A 1 723 ? 150.992 145.962 176.953 1.00 37.87  ? 723  LEU A CD2 1 
ATOM   4614 N  N   . PRO A 1 724 ? 153.458 147.946 179.894 1.00 30.87  ? 724  PRO A N   1 
ATOM   4615 C  CA  . PRO A 1 724 ? 154.251 149.151 180.131 1.00 30.87  ? 724  PRO A CA  1 
ATOM   4616 C  C   . PRO A 1 724 ? 153.444 150.323 179.595 1.00 30.87  ? 724  PRO A C   1 
ATOM   4617 O  O   . PRO A 1 724 ? 153.159 151.261 180.328 1.00 30.87  ? 724  PRO A O   1 
ATOM   4618 C  CB  . PRO A 1 724 ? 155.477 148.933 179.264 1.00 30.87  ? 724  PRO A CB  1 
ATOM   4619 C  CG  . PRO A 1 724 ? 155.582 147.461 179.135 1.00 30.87  ? 724  PRO A CG  1 
ATOM   4620 C  CD  . PRO A 1 724 ? 154.174 146.972 179.062 1.00 30.87  ? 724  PRO A CD  1 
ATOM   4621 N  N   . MET A 1 725 ? 153.106 150.280 178.312 1.00 28.84  ? 725  MET A N   1 
ATOM   4622 C  CA  . MET A 1 725 ? 152.260 151.301 177.708 1.00 28.84  ? 725  MET A CA  1 
ATOM   4623 C  C   . MET A 1 725 ? 151.253 150.579 176.819 1.00 28.84  ? 725  MET A C   1 
ATOM   4624 O  O   . MET A 1 725 ? 151.613 149.643 176.132 1.00 28.84  ? 725  MET A O   1 
ATOM   4625 C  CB  . MET A 1 725 ? 153.084 152.318 176.923 1.00 28.84  ? 725  MET A CB  1 
ATOM   4626 C  CG  . MET A 1 725 ? 152.446 153.697 176.849 1.00 28.84  ? 725  MET A CG  1 
ATOM   4627 S  SD  . MET A 1 725 ? 153.524 154.999 176.218 1.00 28.84  ? 725  MET A SD  1 
ATOM   4628 C  CE  . MET A 1 725 ? 154.964 154.764 177.241 1.00 28.84  ? 725  MET A CE  1 
ATOM   4629 N  N   . LEU A 1 726 ? 149.999 151.013 176.820 1.00 30.31  ? 726  LEU A N   1 
ATOM   4630 C  CA  . LEU A 1 726 ? 148.955 150.367 176.021 1.00 30.31  ? 726  LEU A CA  1 
ATOM   4631 C  C   . LEU A 1 726 ? 149.068 150.734 174.555 1.00 30.31  ? 726  LEU A C   1 
ATOM   4632 O  O   . LEU A 1 726 ? 149.715 151.718 174.234 1.00 30.31  ? 726  LEU A O   1 
ATOM   4633 C  CB  . LEU A 1 726 ? 147.589 150.819 176.518 1.00 30.31  ? 726  LEU A CB  1 
ATOM   4634 C  CG  . LEU A 1 726 ? 147.206 150.454 177.942 1.00 30.31  ? 726  LEU A CG  1 
ATOM   4635 C  CD1 . LEU A 1 726 ? 146.532 151.636 178.605 1.00 30.31  ? 726  LEU A CD1 1 
ATOM   4636 C  CD2 . LEU A 1 726 ? 146.296 149.243 177.935 1.00 30.31  ? 726  LEU A CD2 1 
ATOM   4637 N  N   . PRO A 1 727 ? 148.435 149.954 173.659 1.00 31.44  ? 727  PRO A N   1 
ATOM   4638 C  CA  . PRO A 1 727 ? 148.519 150.331 172.252 1.00 31.44  ? 727  PRO A CA  1 
ATOM   4639 C  C   . PRO A 1 727 ? 147.959 151.728 172.024 1.00 31.44  ? 727  PRO A C   1 
ATOM   4640 O  O   . PRO A 1 727 ? 148.566 152.498 171.299 1.00 31.44  ? 727  PRO A O   1 
ATOM   4641 C  CB  . PRO A 1 727 ? 147.625 149.304 171.580 1.00 31.44  ? 727  PRO A CB  1 
ATOM   4642 C  CG  . PRO A 1 727 ? 147.709 148.113 172.467 1.00 31.44  ? 727  PRO A CG  1 
ATOM   4643 C  CD  . PRO A 1 727 ? 147.748 148.672 173.851 1.00 31.44  ? 727  PRO A CD  1 
ATOM   4644 N  N   . LEU A 1 728 ? 146.844 152.067 172.654 1.00 35.33  ? 728  LEU A N   1 
ATOM   4645 C  CA  . LEU A 1 728 ? 146.284 153.397 172.503 1.00 35.33  ? 728  LEU A CA  1 
ATOM   4646 C  C   . LEU A 1 728 ? 147.302 154.431 172.946 1.00 35.33  ? 728  LEU A C   1 
ATOM   4647 O  O   . LEU A 1 728 ? 147.279 155.555 172.478 1.00 35.33  ? 728  LEU A O   1 
ATOM   4648 C  CB  . LEU A 1 728 ? 145.007 153.544 173.320 1.00 35.33  ? 728  LEU A CB  1 
ATOM   4649 C  CG  . LEU A 1 728 ? 144.142 154.765 173.021 1.00 35.33  ? 728  LEU A CG  1 
ATOM   4650 C  CD1 . LEU A 1 728 ? 142.798 154.612 173.707 1.00 35.33  ? 728  LEU A CD1 1 
ATOM   4651 C  CD2 . LEU A 1 728 ? 144.814 156.051 173.458 1.00 35.33  ? 728  LEU A CD2 1 
ATOM   4652 N  N   . HIS A 1 729 ? 148.192 154.061 173.859 1.00 30.78  ? 729  HIS A N   1 
ATOM   4653 C  CA  . HIS A 1 729 ? 149.206 154.996 174.300 1.00 30.78  ? 729  HIS A CA  1 
ATOM   4654 C  C   . HIS A 1 729 ? 150.304 155.091 173.263 1.00 30.78  ? 729  HIS A C   1 
ATOM   4655 O  O   . HIS A 1 729 ? 150.750 156.180 172.936 1.00 30.78  ? 729  HIS A O   1 
ATOM   4656 C  CB  . HIS A 1 729 ? 149.808 154.553 175.625 1.00 30.78  ? 729  HIS A CB  1 
ATOM   4657 C  CG  . HIS A 1 729 ? 148.902 154.745 176.797 1.00 30.78  ? 729  HIS A CG  1 
ATOM   4658 N  ND1 . HIS A 1 729 ? 148.184 153.714 177.358 1.00 30.78  ? 729  HIS A ND1 1 
ATOM   4659 C  CD2 . HIS A 1 729 ? 148.604 155.848 177.520 1.00 30.78  ? 729  HIS A CD2 1 
ATOM   4660 C  CE1 . HIS A 1 729 ? 147.479 154.174 178.375 1.00 30.78  ? 729  HIS A CE1 1 
ATOM   4661 N  NE2 . HIS A 1 729 ? 147.716 155.466 178.494 1.00 30.78  ? 729  HIS A NE2 1 
ATOM   4662 N  N   . LEU A 1 730 ? 150.745 153.948 172.747 1.00 26.96  ? 730  LEU A N   1 
ATOM   4663 C  CA  . LEU A 1 730 ? 151.790 153.927 171.731 1.00 26.96  ? 730  LEU A CA  1 
ATOM   4664 C  C   . LEU A 1 730 ? 151.341 154.551 170.424 1.00 26.96  ? 730  LEU A C   1 
ATOM   4665 O  O   . LEU A 1 730 ? 152.088 155.280 169.800 1.00 26.96  ? 730  LEU A O   1 
ATOM   4666 C  CB  . LEU A 1 730 ? 152.326 152.523 171.501 1.00 26.96  ? 730  LEU A CB  1 
ATOM   4667 C  CG  . LEU A 1 730 ? 153.138 151.963 172.658 1.00 26.96  ? 730  LEU A CG  1 
ATOM   4668 C  CD1 . LEU A 1 730 ? 153.713 150.605 172.326 1.00 26.96  ? 730  LEU A CD1 1 
ATOM   4669 C  CD2 . LEU A 1 730 ? 154.246 152.924 173.003 1.00 26.96  ? 730  LEU A CD2 1 
ATOM   4670 N  N   . LEU A 1 731 ? 150.112 154.277 170.012 1.00 28.73  ? 731  LEU A N   1 
ATOM   4671 C  CA  . LEU A 1 731 ? 149.610 154.832 168.765 1.00 28.73  ? 731  LEU A CA  1 
ATOM   4672 C  C   . LEU A 1 731 ? 149.561 156.351 168.776 1.00 28.73  ? 731  LEU A C   1 
ATOM   4673 O  O   . LEU A 1 731 ? 149.924 156.977 167.798 1.00 28.73  ? 731  LEU A O   1 
ATOM   4674 C  CB  . LEU A 1 731 ? 148.241 154.271 168.431 1.00 28.73  ? 731  LEU A CB  1 
ATOM   4675 C  CG  . LEU A 1 731 ? 147.560 155.019 167.294 1.00 28.73  ? 731  LEU A CG  1 
ATOM   4676 C  CD1 . LEU A 1 731 ? 148.563 155.282 166.192 1.00 28.73  ? 731  LEU A CD1 1 
ATOM   4677 C  CD2 . LEU A 1 731 ? 146.372 154.237 166.766 1.00 28.73  ? 731  LEU A CD2 1 
ATOM   4678 N  N   . ILE A 1 732 ? 149.101 156.945 169.872 1.00 25.39  ? 732  ILE A N   1 
ATOM   4679 C  CA  . ILE A 1 732 ? 149.036 158.398 169.995 1.00 25.39  ? 732  ILE A CA  1 
ATOM   4680 C  C   . ILE A 1 732 ? 150.436 158.997 170.038 1.00 25.39  ? 732  ILE A C   1 
ATOM   4681 O  O   . ILE A 1 732 ? 150.687 160.066 169.466 1.00 25.39  ? 732  ILE A O   1 
ATOM   4682 C  CB  . ILE A 1 732 ? 148.207 158.792 171.228 1.00 25.39  ? 732  ILE A CB  1 
ATOM   4683 C  CG1 . ILE A 1 732 ? 146.750 158.396 171.014 1.00 25.39  ? 732  ILE A CG1 1 
ATOM   4684 C  CG2 . ILE A 1 732 ? 148.310 160.277 171.488 1.00 25.39  ? 732  ILE A CG2 1 
ATOM   4685 C  CD1 . ILE A 1 732 ? 146.165 158.946 169.742 1.00 25.39  ? 732  ILE A CD1 1 
ATOM   4686 N  N   . GLN A 1 733 ? 151.370 158.318 170.705 1.00 23.06  ? 733  GLN A N   1 
ATOM   4687 C  CA  . GLN A 1 733 ? 152.752 158.783 170.733 1.00 23.06  ? 733  GLN A CA  1 
ATOM   4688 C  C   . GLN A 1 733 ? 153.337 158.835 169.328 1.00 23.06  ? 733  GLN A C   1 
ATOM   4689 O  O   . GLN A 1 733 ? 153.968 159.825 168.937 1.00 23.06  ? 733  GLN A O   1 
ATOM   4690 C  CB  . GLN A 1 733 ? 153.575 157.860 171.627 1.00 23.06  ? 733  GLN A CB  1 
ATOM   4691 C  CG  . GLN A 1 733 ? 155.032 158.216 171.744 1.00 23.06  ? 733  GLN A CG  1 
ATOM   4692 C  CD  . GLN A 1 733 ? 155.803 157.165 172.505 1.00 23.06  ? 733  GLN A CD  1 
ATOM   4693 O  OE1 . GLN A 1 733 ? 156.770 157.462 173.192 1.00 23.06  ? 733  GLN A OE1 1 
ATOM   4694 N  NE2 . GLN A 1 733 ? 155.386 155.921 172.366 1.00 23.06  ? 733  GLN A NE2 1 
ATOM   4695 N  N   . ASN A 1 734 ? 153.115 157.777 168.545 1.00 25.96  ? 734  ASN A N   1 
ATOM   4696 C  CA  . ASN A 1 734 ? 153.593 157.749 167.167 1.00 25.96  ? 734  ASN A CA  1 
ATOM   4697 C  C   . ASN A 1 734 ? 152.940 158.840 166.333 1.00 25.96  ? 734  ASN A C   1 
ATOM   4698 O  O   . ASN A 1 734 ? 153.604 159.488 165.518 1.00 25.96  ? 734  ASN A O   1 
ATOM   4699 C  CB  . ASN A 1 734 ? 153.319 156.383 166.545 1.00 25.96  ? 734  ASN A CB  1 
ATOM   4700 C  CG  . ASN A 1 734 ? 154.380 155.373 166.879 1.00 25.96  ? 734  ASN A CG  1 
ATOM   4701 O  OD1 . ASN A 1 734 ? 155.312 155.661 167.625 1.00 25.96  ? 734  ASN A OD1 1 
ATOM   4702 N  ND2 . ASN A 1 734 ? 154.246 154.176 166.327 1.00 25.96  ? 734  ASN A ND2 1 
ATOM   4703 N  N   . LEU A 1 735 ? 151.635 159.043 166.506 1.00 27.46  ? 735  LEU A N   1 
ATOM   4704 C  CA  . LEU A 1 735 ? 150.943 160.059 165.725 1.00 27.46  ? 735  LEU A CA  1 
ATOM   4705 C  C   . LEU A 1 735 ? 151.485 161.447 166.027 1.00 27.46  ? 735  LEU A C   1 
ATOM   4706 O  O   . LEU A 1 735 ? 151.710 162.245 165.111 1.00 27.46  ? 735  LEU A O   1 
ATOM   4707 C  CB  . LEU A 1 735 ? 149.444 160.001 166.000 1.00 27.46  ? 735  LEU A CB  1 
ATOM   4708 C  CG  . LEU A 1 735 ? 148.590 160.922 165.135 1.00 27.46  ? 735  LEU A CG  1 
ATOM   4709 C  CD1 . LEU A 1 735 ? 148.612 160.440 163.702 1.00 27.46  ? 735  LEU A CD1 1 
ATOM   4710 C  CD2 . LEU A 1 735 ? 147.171 160.993 165.660 1.00 27.46  ? 735  LEU A CD2 1 
ATOM   4711 N  N   . LEU A 1 736 ? 151.711 161.754 167.303 1.00 24.51  ? 736  LEU A N   1 
ATOM   4712 C  CA  . LEU A 1 736 ? 152.237 163.071 167.645 1.00 24.51  ? 736  LEU A CA  1 
ATOM   4713 C  C   . LEU A 1 736 ? 153.672 163.237 167.158 1.00 24.51  ? 736  LEU A C   1 
ATOM   4714 O  O   . LEU A 1 736 ? 154.052 164.314 166.682 1.00 24.51  ? 736  LEU A O   1 
ATOM   4715 C  CB  . LEU A 1 736 ? 152.134 163.304 169.151 1.00 24.51  ? 736  LEU A CB  1 
ATOM   4716 C  CG  . LEU A 1 736 ? 150.708 163.587 169.627 1.00 24.51  ? 736  LEU A CG  1 
ATOM   4717 C  CD1 . LEU A 1 736 ? 150.636 163.676 171.131 1.00 24.51  ? 736  LEU A CD1 1 
ATOM   4718 C  CD2 . LEU A 1 736 ? 150.191 164.863 169.000 1.00 24.51  ? 736  LEU A CD2 1 
ATOM   4719 N  N   . TYR A 1 737 ? 154.482 162.179 167.243 1.00 26.28  ? 737  TYR A N   1 
ATOM   4720 C  CA  . TYR A 1 737 ? 155.842 162.271 166.726 1.00 26.28  ? 737  TYR A CA  1 
ATOM   4721 C  C   . TYR A 1 737 ? 155.848 162.495 165.218 1.00 26.28  ? 737  TYR A C   1 
ATOM   4722 O  O   . TYR A 1 737 ? 156.673 163.252 164.699 1.00 26.28  ? 737  TYR A O   1 
ATOM   4723 C  CB  . TYR A 1 737 ? 156.630 161.015 167.076 1.00 26.28  ? 737  TYR A CB  1 
ATOM   4724 C  CG  . TYR A 1 737 ? 157.952 160.935 166.362 1.00 26.28  ? 737  TYR A CG  1 
ATOM   4725 C  CD1 . TYR A 1 737 ? 158.999 161.763 166.720 1.00 26.28  ? 737  TYR A CD1 1 
ATOM   4726 C  CD2 . TYR A 1 737 ? 158.155 160.035 165.331 1.00 26.28  ? 737  TYR A CD2 1 
ATOM   4727 C  CE1 . TYR A 1 737 ? 160.211 161.699 166.076 1.00 26.28  ? 737  TYR A CE1 1 
ATOM   4728 C  CE2 . TYR A 1 737 ? 159.364 159.964 164.681 1.00 26.28  ? 737  TYR A CE2 1 
ATOM   4729 C  CZ  . TYR A 1 737 ? 160.388 160.799 165.060 1.00 26.28  ? 737  TYR A CZ  1 
ATOM   4730 O  OH  . TYR A 1 737 ? 161.600 160.739 164.420 1.00 26.28  ? 737  TYR A OH  1 
ATOM   4731 N  N   . ASP A 1 738 ? 154.940 161.839 164.494 1.00 29.38  ? 738  ASP A N   1 
ATOM   4732 C  CA  . ASP A 1 738 ? 154.870 162.037 163.049 1.00 29.38  ? 738  ASP A CA  1 
ATOM   4733 C  C   . ASP A 1 738 ? 154.350 163.428 162.706 1.00 29.38  ? 738  ASP A C   1 
ATOM   4734 O  O   . ASP A 1 738 ? 154.773 164.032 161.713 1.00 29.38  ? 738  ASP A O   1 
ATOM   4735 C  CB  . ASP A 1 738 ? 153.996 160.955 162.422 1.00 29.38  ? 738  ASP A CB  1 
ATOM   4736 C  CG  . ASP A 1 738 ? 154.645 159.589 162.467 1.00 29.38  ? 738  ASP A CG  1 
ATOM   4737 O  OD1 . ASP A 1 738 ? 155.652 159.436 163.186 1.00 29.38  ? 738  ASP A OD1 1 
ATOM   4738 O  OD2 . ASP A 1 738 ? 154.144 158.665 161.795 1.00 29.38  ? 738  ASP A OD2 1 
ATOM   4739 N  N   . VAL A 1 739 ? 153.430 163.953 163.516 1.00 29.16  ? 739  VAL A N   1 
ATOM   4740 C  CA  . VAL A 1 739 ? 153.012 165.342 163.353 1.00 29.16  ? 739  VAL A CA  1 
ATOM   4741 C  C   . VAL A 1 739 ? 154.205 166.271 163.522 1.00 29.16  ? 739  VAL A C   1 
ATOM   4742 O  O   . VAL A 1 739 ? 154.344 167.267 162.804 1.00 29.16  ? 739  VAL A O   1 
ATOM   4743 C  CB  . VAL A 1 739 ? 151.880 165.678 164.340 1.00 29.16  ? 739  VAL A CB  1 
ATOM   4744 C  CG1 . VAL A 1 739 ? 151.788 167.178 164.562 1.00 29.16  ? 739  VAL A CG1 1 
ATOM   4745 C  CG2 . VAL A 1 739 ? 150.561 165.137 163.819 1.00 29.16  ? 739  VAL A CG2 1 
ATOM   4746 N  N   . SER A 1 740 ? 155.124 165.878 164.385 1.00 28.64  ? 740  SER A N   1 
ATOM   4747 C  CA  . SER A 1 740 ? 156.341 166.641 164.544 1.00 28.64  ? 740  SER A CA  1 
ATOM   4748 C  C   . SER A 1 740 ? 157.277 166.315 163.394 1.00 28.64  ? 740  SER A C   1 
ATOM   4749 O  O   . SER A 1 740 ? 158.240 167.022 163.173 1.00 28.64  ? 740  SER A O   1 
ATOM   4750 C  CB  . SER A 1 740 ? 157.035 166.297 165.849 1.00 28.64  ? 740  SER A CB  1 
ATOM   4751 O  OG  . SER A 1 740 ? 158.419 166.582 165.756 1.00 28.64  ? 740  SER A OG  1 
ATOM   4752 N  N   . GLN A 1 741 ? 157.009 165.234 162.668 1.00 29.23  ? 741  GLN A N   1 
ATOM   4753 C  CA  . GLN A 1 741 ? 157.849 164.846 161.539 1.00 29.23  ? 741  GLN A CA  1 
ATOM   4754 C  C   . GLN A 1 741 ? 157.390 165.463 160.239 1.00 29.23  ? 741  GLN A C   1 
ATOM   4755 O  O   . GLN A 1 741 ? 157.995 165.260 159.199 1.00 29.23  ? 741  GLN A O   1 
ATOM   4756 C  CB  . GLN A 1 741 ? 157.943 163.336 161.390 1.00 29.23  ? 741  GLN A CB  1 
ATOM   4757 C  CG  . GLN A 1 741 ? 158.863 162.678 162.391 1.00 29.23  ? 741  GLN A CG  1 
ATOM   4758 C  CD  . GLN A 1 741 ? 160.220 163.323 162.442 1.00 29.23  ? 741  GLN A CD  1 
ATOM   4759 O  OE1 . GLN A 1 741 ? 160.344 164.539 162.509 1.00 29.23  ? 741  GLN A OE1 1 
ATOM   4760 N  NE2 . GLN A 1 741 ? 161.250 162.504 162.431 1.00 29.23  ? 741  GLN A NE2 1 
ATOM   4761 N  N   . VAL A 1 742 ? 156.305 166.227 160.301 1.00 29.49  ? 742  VAL A N   1 
ATOM   4762 C  CA  . VAL A 1 742 ? 155.759 166.939 159.150 1.00 29.49  ? 742  VAL A CA  1 
ATOM   4763 C  C   . VAL A 1 742 ? 156.661 168.073 158.669 1.00 29.49  ? 742  VAL A C   1 
ATOM   4764 O  O   . VAL A 1 742 ? 156.565 168.489 157.531 1.00 29.49  ? 742  VAL A O   1 
ATOM   4765 C  CB  . VAL A 1 742 ? 154.339 167.463 159.404 1.00 29.49  ? 742  VAL A CB  1 
ATOM   4766 C  CG1 . VAL A 1 742 ? 154.099 168.739 158.622 1.00 29.49  ? 742  VAL A CG1 1 
ATOM   4767 C  CG2 . VAL A 1 742 ? 153.320 166.403 159.027 1.00 29.49  ? 742  VAL A CG2 1 
ATOM   4768 N  N   . ALA A 1 743 ? 157.488 168.608 159.561 1.00 30.65  ? 743  ALA A N   1 
ATOM   4769 C  CA  . ALA A 1 743 ? 158.418 169.669 159.245 1.00 30.65  ? 743  ALA A CA  1 
ATOM   4770 C  C   . ALA A 1 743 ? 159.743 169.136 158.716 1.00 30.65  ? 743  ALA A C   1 
ATOM   4771 O  O   . ALA A 1 743 ? 160.640 169.916 158.440 1.00 30.65  ? 743  ALA A O   1 
ATOM   4772 C  CB  . ALA A 1 743 ? 158.661 170.536 160.463 1.00 30.65  ? 743  ALA A CB  1 
ATOM   4773 N  N   . ILE A 1 744 ? 159.893 167.820 158.590 1.00 28.93  ? 744  ILE A N   1 
ATOM   4774 C  CA  . ILE A 1 744 ? 161.153 167.275 158.078 1.00 28.93  ? 744  ILE A CA  1 
ATOM   4775 C  C   . ILE A 1 744 ? 161.510 167.740 156.658 1.00 28.93  ? 744  ILE A C   1 
ATOM   4776 O  O   . ILE A 1 744 ? 162.658 168.072 156.408 1.00 28.93  ? 744  ILE A O   1 
ATOM   4777 C  CB  . ILE A 1 744 ? 161.300 165.743 158.278 1.00 28.93  ? 744  ILE A CB  1 
ATOM   4778 C  CG1 . ILE A 1 744 ? 162.769 165.351 158.329 1.00 28.93  ? 744  ILE A CG1 1 
ATOM   4779 C  CG2 . ILE A 1 744 ? 160.572 164.932 157.218 1.00 28.93  ? 744  ILE A CG2 1 
ATOM   4780 C  CD1 . ILE A 1 744 ? 163.419 165.636 159.660 1.00 28.93  ? 744  ILE A CD1 1 
ATOM   4781 N  N   . PRO A 1 745 ? 160.537 167.800 155.730 1.00 30.15  ? 745  PRO A N   1 
ATOM   4782 C  CA  . PRO A 1 745 ? 160.890 168.274 154.381 1.00 30.15  ? 745  PRO A CA  1 
ATOM   4783 C  C   . PRO A 1 745 ? 161.490 169.662 154.366 1.00 30.15  ? 745  PRO A C   1 
ATOM   4784 O  O   . PRO A 1 745 ? 162.128 170.031 153.374 1.00 30.15  ? 745  PRO A O   1 
ATOM   4785 C  CB  . PRO A 1 745 ? 159.554 168.243 153.629 1.00 30.15  ? 745  PRO A CB  1 
ATOM   4786 C  CG  . PRO A 1 745 ? 158.712 167.320 154.385 1.00 30.15  ? 745  PRO A CG  1 
ATOM   4787 C  CD  . PRO A 1 745 ? 159.092 167.518 155.806 1.00 30.15  ? 745  PRO A CD  1 
ATOM   4788 N  N   . PHE A 1 746 ? 161.303 170.444 155.423 1.00 32.06  ? 746  PHE A N   1 
ATOM   4789 C  CA  . PHE A 1 746 ? 161.830 171.797 155.495 1.00 32.06  ? 746  PHE A CA  1 
ATOM   4790 C  C   . PHE A 1 746 ? 163.155 171.868 156.241 1.00 32.06  ? 746  PHE A C   1 
ATOM   4791 O  O   . PHE A 1 746 ? 163.634 172.968 156.524 1.00 32.06  ? 746  PHE A O   1 
ATOM   4792 C  CB  . PHE A 1 746 ? 160.812 172.725 156.163 1.00 32.06  ? 746  PHE A CB  1 
ATOM   4793 C  CG  . PHE A 1 746 ? 159.462 172.740 155.496 1.00 32.06  ? 746  PHE A CG  1 
ATOM   4794 C  CD1 . PHE A 1 746 ? 159.304 172.311 154.193 1.00 32.06  ? 746  PHE A CD1 1 
ATOM   4795 C  CD2 . PHE A 1 746 ? 158.349 173.183 156.184 1.00 32.06  ? 746  PHE A CD2 1 
ATOM   4796 C  CE1 . PHE A 1 746 ? 158.066 172.323 153.594 1.00 32.06  ? 746  PHE A CE1 1 
ATOM   4797 C  CE2 . PHE A 1 746 ? 157.110 173.198 155.585 1.00 32.06  ? 746  PHE A CE2 1 
ATOM   4798 C  CZ  . PHE A 1 746 ? 156.969 172.766 154.290 1.00 32.06  ? 746  PHE A CZ  1 
ATOM   4799 N  N   . ASP A 1 747 ? 163.748 170.724 156.569 1.00 35.02  ? 747  ASP A N   1 
ATOM   4800 C  CA  . ASP A 1 747 ? 164.989 170.690 157.325 1.00 35.02  ? 747  ASP A CA  1 
ATOM   4801 C  C   . ASP A 1 747 ? 166.169 171.122 156.455 1.00 35.02  ? 747  ASP A C   1 
ATOM   4802 O  O   . ASP A 1 747 ? 166.097 171.159 155.225 1.00 35.02  ? 747  ASP A O   1 
ATOM   4803 C  CB  . ASP A 1 747 ? 165.230 169.290 157.882 1.00 35.02  ? 747  ASP A CB  1 
ATOM   4804 C  CG  . ASP A 1 747 ? 166.200 169.286 159.038 1.00 35.02  ? 747  ASP A CG  1 
ATOM   4805 O  OD1 . ASP A 1 747 ? 166.151 170.225 159.857 1.00 35.02  ? 747  ASP A OD1 1 
ATOM   4806 O  OD2 . ASP A 1 747 ? 167.015 168.346 159.126 1.00 35.02  ? 747  ASP A OD2 1 
ATOM   4807 N  N   . ASN A 1 748 ? 167.275 171.449 157.120 1.00 36.94  ? 748  ASN A N   1 
ATOM   4808 C  CA  . ASN A 1 748 ? 168.502 171.896 156.469 1.00 36.94  ? 748  ASN A CA  1 
ATOM   4809 C  C   . ASN A 1 748 ? 169.483 170.732 156.438 1.00 36.94  ? 748  ASN A C   1 
ATOM   4810 O  O   . ASN A 1 748 ? 170.022 170.341 157.479 1.00 36.94  ? 748  ASN A O   1 
ATOM   4811 C  CB  . ASN A 1 748 ? 169.099 173.091 157.204 1.00 36.94  ? 748  ASN A CB  1 
ATOM   4812 C  CG  . ASN A 1 748 ? 168.475 174.401 156.786 1.00 36.94  ? 748  ASN A CG  1 
ATOM   4813 O  OD1 . ASN A 1 748 ? 167.931 174.520 155.689 1.00 36.94  ? 748  ASN A OD1 1 
ATOM   4814 N  ND2 . ASN A 1 748 ? 168.544 175.394 157.663 1.00 36.94  ? 748  ASN A ND2 1 
ATOM   4815 N  N   . VAL A 1 749 ? 169.721 170.188 155.250 1.00 35.82  ? 749  VAL A N   1 
ATOM   4816 C  CA  . VAL A 1 749 ? 170.603 169.038 155.097 1.00 35.82  ? 749  VAL A CA  1 
ATOM   4817 C  C   . VAL A 1 749 ? 172.051 169.503 155.121 1.00 35.82  ? 749  VAL A C   1 
ATOM   4818 O  O   . VAL A 1 749 ? 172.421 170.455 154.425 1.00 35.82  ? 749  VAL A O   1 
ATOM   4819 C  CB  . VAL A 1 749 ? 170.292 168.281 153.799 1.00 35.82  ? 749  VAL A CB  1 
ATOM   4820 C  CG1 . VAL A 1 749 ? 171.267 167.146 153.614 1.00 35.82  ? 749  VAL A CG1 1 
ATOM   4821 C  CG2 . VAL A 1 749 ? 168.880 167.756 153.828 1.00 35.82  ? 749  VAL A CG2 1 
ATOM   4822 N  N   . ASP A 1 750 ? 172.871 168.833 155.925 1.00 41.06  ? 750  ASP A N   1 
ATOM   4823 C  CA  . ASP A 1 750 ? 174.297 169.116 155.947 1.00 41.06  ? 750  ASP A CA  1 
ATOM   4824 C  C   . ASP A 1 750 ? 174.926 168.770 154.604 1.00 41.06  ? 750  ASP A C   1 
ATOM   4825 O  O   . ASP A 1 750 ? 174.534 167.809 153.939 1.00 41.06  ? 750  ASP A O   1 
ATOM   4826 C  CB  . ASP A 1 750 ? 174.980 168.326 157.061 1.00 41.06  ? 750  ASP A CB  1 
ATOM   4827 C  CG  . ASP A 1 750 ? 174.783 168.950 158.420 1.00 41.06  ? 750  ASP A CG  1 
ATOM   4828 O  OD1 . ASP A 1 750 ? 174.316 170.105 158.482 1.00 41.06  ? 750  ASP A OD1 1 
ATOM   4829 O  OD2 . ASP A 1 750 ? 175.098 168.288 159.428 1.00 41.06  ? 750  ASP A OD2 1 
ATOM   4830 N  N   . ASP A 1 751 ? 175.923 169.565 154.210 1.00 41.63  ? 751  ASP A N   1 
ATOM   4831 C  CA  . ASP A 1 751 ? 176.563 169.370 152.915 1.00 41.63  ? 751  ASP A CA  1 
ATOM   4832 C  C   . ASP A 1 751 ? 177.246 168.016 152.803 1.00 41.63  ? 751  ASP A C   1 
ATOM   4833 O  O   . ASP A 1 751 ? 177.517 167.563 151.688 1.00 41.63  ? 751  ASP A O   1 
ATOM   4834 C  CB  . ASP A 1 751 ? 177.576 170.484 152.659 1.00 41.63  ? 751  ASP A CB  1 
ATOM   4835 C  CG  . ASP A 1 751 ? 176.933 171.741 152.111 1.00 41.63  ? 751  ASP A CG  1 
ATOM   4836 O  OD1 . ASP A 1 751 ? 175.843 171.639 151.512 1.00 41.63  ? 751  ASP A OD1 1 
ATOM   4837 O  OD2 . ASP A 1 751 ? 177.518 172.831 152.281 1.00 41.63  ? 751  ASP A OD2 1 
ATOM   4838 N  N   . GLU A 1 752 ? 177.539 167.367 153.929 1.00 42.81  ? 752  GLU A N   1 
ATOM   4839 C  CA  . GLU A 1 752 ? 178.134 166.036 153.882 1.00 42.81  ? 752  GLU A CA  1 
ATOM   4840 C  C   . GLU A 1 752 ? 177.175 165.020 153.276 1.00 42.81  ? 752  GLU A C   1 
ATOM   4841 O  O   . GLU A 1 752 ? 177.596 164.131 152.528 1.00 42.81  ? 752  GLU A O   1 
ATOM   4842 C  CB  . GLU A 1 752 ? 178.555 165.604 155.284 1.00 42.81  ? 752  GLU A CB  1 
ATOM   4843 C  CG  . GLU A 1 752 ? 179.386 164.340 155.315 1.00 42.81  ? 752  GLU A CG  1 
ATOM   4844 C  CD  . GLU A 1 752 ? 179.742 163.920 156.724 1.00 42.81  ? 752  GLU A CD  1 
ATOM   4845 O  OE1 . GLU A 1 752 ? 178.891 164.085 157.623 1.00 42.81  ? 752  GLU A OE1 1 
ATOM   4846 O  OE2 . GLU A 1 752 ? 180.870 163.426 156.934 1.00 42.81  ? 752  GLU A OE2 1 
ATOM   4847 N  N   . GLN A 1 753 ? 175.885 165.126 153.601 1.00 38.03  ? 753  GLN A N   1 
ATOM   4848 C  CA  . GLN A 1 753 ? 174.912 164.155 153.111 1.00 38.03  ? 753  GLN A CA  1 
ATOM   4849 C  C   . GLN A 1 753 ? 174.731 164.249 151.601 1.00 38.03  ? 753  GLN A C   1 
ATOM   4850 O  O   . GLN A 1 753 ? 174.652 163.224 150.916 1.00 38.03  ? 753  GLN A O   1 
ATOM   4851 C  CB  . GLN A 1 753 ? 173.570 164.352 153.817 1.00 38.03  ? 753  GLN A CB  1 
ATOM   4852 C  CG  . GLN A 1 753 ? 173.361 163.489 155.051 1.00 38.03  ? 753  GLN A CG  1 
ATOM   4853 C  CD  . GLN A 1 753 ? 173.773 164.180 156.335 1.00 38.03  ? 753  GLN A CD  1 
ATOM   4854 O  OE1 . GLN A 1 753 ? 173.297 165.269 156.647 1.00 38.03  ? 753  GLN A OE1 1 
ATOM   4855 N  NE2 . GLN A 1 753 ? 174.651 163.538 157.096 1.00 38.03  ? 753  GLN A NE2 1 
ATOM   4856 N  N   . ILE A 1 754 ? 174.598 165.452 151.069 1.00 36.37  ? 754  ILE A N   1 
ATOM   4857 C  CA  . ILE A 1 754 ? 174.363 165.579 149.643 1.00 36.37  ? 754  ILE A CA  1 
ATOM   4858 C  C   . ILE A 1 754 ? 175.623 165.670 148.808 1.00 36.37  ? 754  ILE A C   1 
ATOM   4859 O  O   . ILE A 1 754 ? 175.609 166.268 147.740 1.00 36.37  ? 754  ILE A O   1 
ATOM   4860 C  CB  . ILE A 1 754 ? 173.508 166.806 149.340 1.00 36.37  ? 754  ILE A CB  1 
ATOM   4861 C  CG1 . ILE A 1 754 ? 174.323 168.069 149.521 1.00 36.37  ? 754  ILE A CG1 1 
ATOM   4862 C  CG2 . ILE A 1 754 ? 172.319 166.854 150.270 1.00 36.37  ? 754  ILE A CG2 1 
ATOM   4863 C  CD1 . ILE A 1 754 ? 173.467 169.312 149.556 1.00 36.37  ? 754  ILE A CD1 1 
ATOM   4864 N  N   . GLN A 1 755 ? 176.716 165.094 149.288 1.00 39.32  ? 755  GLN A N   1 
ATOM   4865 C  CA  . GLN A 1 755 ? 177.964 165.153 148.539 1.00 39.32  ? 755  GLN A CA  1 
ATOM   4866 C  C   . GLN A 1 755 ? 178.226 163.963 147.637 1.00 39.32  ? 755  GLN A C   1 
ATOM   4867 O  O   . GLN A 1 755 ? 179.207 163.954 146.912 1.00 39.32  ? 755  GLN A O   1 
ATOM   4868 C  CB  . GLN A 1 755 ? 179.146 165.339 149.479 1.00 39.32  ? 755  GLN A CB  1 
ATOM   4869 C  CG  . GLN A 1 755 ? 180.355 165.930 148.790 1.00 39.32  ? 755  GLN A CG  1 
ATOM   4870 C  CD  . GLN A 1 755 ? 180.054 167.282 148.184 1.00 39.32  ? 755  GLN A CD  1 
ATOM   4871 O  OE1 . GLN A 1 755 ? 178.900 167.611 147.923 1.00 39.32  ? 755  GLN A OE1 1 
ATOM   4872 N  NE2 . GLN A 1 755 ? 181.092 168.075 147.962 1.00 39.32  ? 755  GLN A NE2 1 
ATOM   4873 N  N   . LYS A 1 756 ? 177.358 162.962 147.688 1.00 39.71  ? 756  LYS A N   1 
ATOM   4874 C  CA  . LYS A 1 756 ? 177.504 161.755 146.879 1.00 39.71  ? 756  LYS A CA  1 
ATOM   4875 C  C   . LYS A 1 756 ? 176.133 161.238 146.505 1.00 39.71  ? 756  LYS A C   1 
ATOM   4876 O  O   . LYS A 1 756 ? 175.148 161.643 147.105 1.00 39.71  ? 756  LYS A O   1 
ATOM   4877 C  CB  . LYS A 1 756 ? 178.270 160.676 147.638 1.00 39.71  ? 756  LYS A CB  1 
ATOM   4878 C  CG  . LYS A 1 756 ? 179.773 160.873 147.643 1.00 39.71  ? 756  LYS A CG  1 
ATOM   4879 C  CD  . LYS A 1 756 ? 180.307 161.008 146.227 1.00 39.71  ? 756  LYS A CD  1 
ATOM   4880 C  CE  . LYS A 1 756 ? 181.685 161.648 146.212 1.00 39.71  ? 756  LYS A CE  1 
ATOM   4881 N  NZ  . LYS A 1 756 ? 182.147 161.952 144.830 1.00 39.71  ? 756  LYS A NZ  1 
ATOM   4882 N  N   . PRO A 1 757 ? 176.055 160.341 145.514 1.00 40.12  ? 757  PRO A N   1 
ATOM   4883 C  CA  . PRO A 1 757 ? 174.739 159.827 145.135 1.00 40.12  ? 757  PRO A CA  1 
ATOM   4884 C  C   . PRO A 1 757 ? 174.064 159.142 146.318 1.00 40.12  ? 757  PRO A C   1 
ATOM   4885 O  O   . PRO A 1 757 ? 174.704 158.388 147.037 1.00 40.12  ? 757  PRO A O   1 
ATOM   4886 C  CB  . PRO A 1 757 ? 175.073 158.798 144.062 1.00 40.12  ? 757  PRO A CB  1 
ATOM   4887 C  CG  . PRO A 1 757 ? 176.336 159.296 143.462 1.00 40.12  ? 757  PRO A CG  1 
ATOM   4888 C  CD  . PRO A 1 757 ? 177.110 159.895 144.595 1.00 40.12  ? 757  PRO A CD  1 
ATOM   4889 N  N   . GLN A 1 758 ? 172.777 159.412 146.502 1.00 39.22  ? 758  GLN A N   1 
ATOM   4890 C  CA  . GLN A 1 758 ? 172.012 158.866 147.610 1.00 39.22  ? 758  GLN A CA  1 
ATOM   4891 C  C   . GLN A 1 758 ? 171.565 157.444 147.364 1.00 39.22  ? 758  GLN A C   1 
ATOM   4892 O  O   . GLN A 1 758 ? 170.743 157.202 146.492 1.00 39.22  ? 758  GLN A O   1 
ATOM   4893 C  CB  . GLN A 1 758 ? 170.775 159.717 147.832 1.00 39.22  ? 758  GLN A CB  1 
ATOM   4894 C  CG  . GLN A 1 758 ? 171.050 161.203 147.851 1.00 39.22  ? 758  GLN A CG  1 
ATOM   4895 C  CD  . GLN A 1 758 ? 172.048 161.573 148.911 1.00 39.22  ? 758  GLN A CD  1 
ATOM   4896 O  OE1 . GLN A 1 758 ? 173.019 160.864 149.129 1.00 39.22  ? 758  GLN A OE1 1 
ATOM   4897 N  NE2 . GLN A 1 758 ? 171.815 162.686 149.578 1.00 39.22  ? 758  GLN A NE2 1 
ATOM   4898 N  N   . ARG A 1 759 ? 172.076 156.506 148.151 1.00 45.39  ? 759  ARG A N   1 
ATOM   4899 C  CA  . ARG A 1 759 ? 171.696 155.111 147.982 1.00 45.39  ? 759  ARG A CA  1 
ATOM   4900 C  C   . ARG A 1 759 ? 170.695 154.694 149.051 1.00 45.39  ? 759  ARG A C   1 
ATOM   4901 O  O   . ARG A 1 759 ? 170.805 155.097 150.212 1.00 45.39  ? 759  ARG A O   1 
ATOM   4902 C  CB  . ARG A 1 759 ? 172.926 154.204 148.035 1.00 45.39  ? 759  ARG A CB  1 
ATOM   4903 C  CG  . ARG A 1 759 ? 173.831 154.330 146.824 1.00 45.39  ? 759  ARG A CG  1 
ATOM   4904 C  CD  . ARG A 1 759 ? 173.044 154.162 145.536 1.00 45.39  ? 759  ARG A CD  1 
ATOM   4905 N  NE  . ARG A 1 759 ? 173.913 154.120 144.367 1.00 45.39  ? 759  ARG A NE  1 
ATOM   4906 C  CZ  . ARG A 1 759 ? 173.796 154.921 143.316 1.00 45.39  ? 759  ARG A CZ  1 
ATOM   4907 N  NH1 . ARG A 1 759 ? 172.848 155.840 143.250 1.00 45.39  ? 759  ARG A NH1 1 
ATOM   4908 N  NH2 . ARG A 1 759 ? 174.652 154.795 142.306 1.00 45.39  ? 759  ARG A NH2 1 
ATOM   4909 N  N   . TRP A 1 760 ? 169.722 153.879 148.650 1.00 48.29  ? 760  TRP A N   1 
ATOM   4910 C  CA  . TRP A 1 760 ? 168.637 153.430 149.519 1.00 48.29  ? 760  TRP A CA  1 
ATOM   4911 C  C   . TRP A 1 760 ? 168.719 151.910 149.618 1.00 48.29  ? 760  TRP A C   1 
ATOM   4912 O  O   . TRP A 1 760 ? 168.410 151.201 148.657 1.00 48.29  ? 760  TRP A O   1 
ATOM   4913 C  CB  . TRP A 1 760 ? 167.288 153.878 148.964 1.00 48.29  ? 760  TRP A CB  1 
ATOM   4914 C  CG  . TRP A 1 760 ? 166.130 153.710 149.906 1.00 48.29  ? 760  TRP A CG  1 
ATOM   4915 C  CD1 . TRP A 1 760 ? 166.057 152.879 150.985 1.00 48.29  ? 760  TRP A CD1 1 
ATOM   4916 C  CD2 . TRP A 1 760 ? 164.864 154.377 149.829 1.00 48.29  ? 760  TRP A CD2 1 
ATOM   4917 N  NE1 . TRP A 1 760 ? 164.832 152.999 151.594 1.00 48.29  ? 760  TRP A NE1 1 
ATOM   4918 C  CE2 . TRP A 1 760 ? 164.081 153.912 150.902 1.00 48.29  ? 760  TRP A CE2 1 
ATOM   4919 C  CE3 . TRP A 1 760 ? 164.320 155.327 148.961 1.00 48.29  ? 760  TRP A CE3 1 
ATOM   4920 C  CZ2 . TRP A 1 760 ? 162.782 154.364 151.128 1.00 48.29  ? 760  TRP A CZ2 1 
ATOM   4921 C  CZ3 . TRP A 1 760 ? 163.031 155.774 149.188 1.00 48.29  ? 760  TRP A CZ3 1 
ATOM   4922 C  CH2 . TRP A 1 760 ? 162.277 155.293 150.262 1.00 48.29  ? 760  TRP A CH2 1 
ATOM   4923 N  N   . ASN A 1 761 ? 169.129 151.410 150.783 1.00 49.29  ? 761  ASN A N   1 
ATOM   4924 C  CA  . ASN A 1 761 ? 169.229 149.976 151.021 1.00 49.29  ? 761  ASN A CA  1 
ATOM   4925 C  C   . ASN A 1 761 ? 168.927 149.682 152.484 1.00 49.29  ? 761  ASN A C   1 
ATOM   4926 O  O   . ASN A 1 761 ? 169.457 150.365 153.377 1.00 49.29  ? 761  ASN A O   1 
ATOM   4927 C  CB  . ASN A 1 761 ? 170.619 149.454 150.648 1.00 49.29  ? 761  ASN A CB  1 
ATOM   4928 C  CG  . ASN A 1 761 ? 171.717 150.416 151.033 1.00 49.29  ? 761  ASN A CG  1 
ATOM   4929 O  OD1 . ASN A 1 761 ? 171.448 151.520 151.504 1.00 49.29  ? 761  ASN A OD1 1 
ATOM   4930 N  ND2 . ASN A 1 761 ? 172.964 150.004 150.837 1.00 49.29  ? 761  ASN A ND2 1 
ATOM   4931 N  N   . PRO A 1 762 ? 168.090 148.683 152.777 1.00 48.32  ? 762  PRO A N   1 
ATOM   4932 C  CA  . PRO A 1 762 ? 167.773 148.369 154.179 1.00 48.32  ? 762  PRO A CA  1 
ATOM   4933 C  C   . PRO A 1 762 ? 168.945 147.815 154.967 1.00 48.32  ? 762  PRO A C   1 
ATOM   4934 O  O   . PRO A 1 762 ? 168.830 147.685 156.192 1.00 48.32  ? 762  PRO A O   1 
ATOM   4935 C  CB  . PRO A 1 762 ? 166.651 147.329 154.060 1.00 48.32  ? 762  PRO A CB  1 
ATOM   4936 C  CG  . PRO A 1 762 ? 166.065 147.563 152.707 1.00 48.32  ? 762  PRO A CG  1 
ATOM   4937 C  CD  . PRO A 1 762 ? 167.236 147.931 151.846 1.00 48.32  ? 762  PRO A CD  1 
ATOM   4938 N  N   . ALA A 1 763 ? 170.059 147.482 154.314 1.00 48.57  ? 763  ALA A N   1 
ATOM   4939 C  CA  . ALA A 1 763 ? 171.200 146.931 155.036 1.00 48.57  ? 763  ALA A CA  1 
ATOM   4940 C  C   . ALA A 1 763 ? 171.734 147.916 156.068 1.00 48.57  ? 763  ALA A C   1 
ATOM   4941 O  O   . ALA A 1 763 ? 172.080 147.525 157.188 1.00 48.57  ? 763  ALA A O   1 
ATOM   4942 C  CB  . ALA A 1 763 ? 172.301 146.533 154.054 1.00 48.57  ? 763  ALA A CB  1 
ATOM   4943 N  N   . ASP A 1 764 ? 171.817 149.199 155.710 1.00 48.83  ? 764  ASP A N   1 
ATOM   4944 C  CA  . ASP A 1 764 ? 172.295 150.195 156.661 1.00 48.83  ? 764  ASP A CA  1 
ATOM   4945 C  C   . ASP A 1 764 ? 171.193 150.681 157.594 1.00 48.83  ? 764  ASP A C   1 
ATOM   4946 O  O   . ASP A 1 764 ? 171.480 151.059 158.734 1.00 48.83  ? 764  ASP A O   1 
ATOM   4947 C  CB  . ASP A 1 764 ? 172.926 151.374 155.923 1.00 48.83  ? 764  ASP A CB  1 
ATOM   4948 C  CG  . ASP A 1 764 ? 173.660 150.945 154.669 1.00 48.83  ? 764  ASP A CG  1 
ATOM   4949 O  OD1 . ASP A 1 764 ? 174.701 150.265 154.792 1.00 48.83  ? 764  ASP A OD1 1 
ATOM   4950 O  OD2 . ASP A 1 764 ? 173.205 151.294 153.562 1.00 48.83  ? 764  ASP A OD2 1 
ATOM   4951 N  N   . LEU A 1 765 ? 169.937 150.670 157.143 1.00 40.03  ? 765  LEU A N   1 
ATOM   4952 C  CA  . LEU A 1 765 ? 168.838 151.021 158.036 1.00 40.03  ? 765  LEU A CA  1 
ATOM   4953 C  C   . LEU A 1 765 ? 168.732 150.032 159.189 1.00 40.03  ? 765  LEU A C   1 
ATOM   4954 O  O   . LEU A 1 765 ? 168.504 150.428 160.339 1.00 40.03  ? 765  LEU A O   1 
ATOM   4955 C  CB  . LEU A 1 765 ? 167.526 151.081 157.254 1.00 40.03  ? 765  LEU A CB  1 
ATOM   4956 C  CG  . LEU A 1 765 ? 166.246 151.275 158.064 1.00 40.03  ? 765  LEU A CG  1 
ATOM   4957 C  CD1 . LEU A 1 765 ? 166.353 152.509 158.932 1.00 40.03  ? 765  LEU A CD1 1 
ATOM   4958 C  CD2 . LEU A 1 765 ? 165.048 151.379 157.141 1.00 40.03  ? 765  LEU A CD2 1 
ATOM   4959 N  N   . GLY A 1 766 ? 168.902 148.741 158.902 1.00 42.49  ? 766  GLY A N   1 
ATOM   4960 C  CA  . GLY A 1 766 ? 168.833 147.746 159.957 1.00 42.49  ? 766  GLY A CA  1 
ATOM   4961 C  C   . GLY A 1 766 ? 169.894 147.948 161.020 1.00 42.49  ? 766  GLY A C   1 
ATOM   4962 O  O   . GLY A 1 766 ? 169.601 147.909 162.217 1.00 42.49  ? 766  GLY A O   1 
ATOM   4963 N  N   . ARG A 1 767 ? 171.137 148.185 160.604 1.00 45.34  ? 767  ARG A N   1 
ATOM   4964 C  CA  . ARG A 1 767 ? 172.193 148.386 161.586 1.00 45.34  ? 767  ARG A CA  1 
ATOM   4965 C  C   . ARG A 1 767 ? 172.084 149.734 162.286 1.00 45.34  ? 767  ARG A C   1 
ATOM   4966 O  O   . ARG A 1 767 ? 172.475 149.836 163.453 1.00 45.34  ? 767  ARG A O   1 
ATOM   4967 C  CB  . ARG A 1 767 ? 173.567 148.222 160.936 1.00 45.34  ? 767  ARG A CB  1 
ATOM   4968 C  CG  . ARG A 1 767 ? 173.742 148.956 159.633 1.00 45.34  ? 767  ARG A CG  1 
ATOM   4969 C  CD  . ARG A 1 767 ? 175.092 148.646 159.013 1.00 45.34  ? 767  ARG A CD  1 
ATOM   4970 N  NE  . ARG A 1 767 ? 176.162 149.418 159.631 1.00 45.34  ? 767  ARG A NE  1 
ATOM   4971 C  CZ  . ARG A 1 767 ? 177.453 149.214 159.411 1.00 45.34  ? 767  ARG A CZ  1 
ATOM   4972 N  NH1 . ARG A 1 767 ? 177.872 148.259 158.599 1.00 45.34  ? 767  ARG A NH1 1 
ATOM   4973 N  NH2 . ARG A 1 767 ? 178.345 149.990 160.021 1.00 45.34  ? 767  ARG A NH2 1 
ATOM   4974 N  N   . PHE A 1 768 ? 171.538 150.760 161.625 1.00 37.40  ? 768  PHE A N   1 
ATOM   4975 C  CA  . PHE A 1 768 ? 171.244 152.001 162.335 1.00 37.40  ? 768  PHE A CA  1 
ATOM   4976 C  C   . PHE A 1 768 ? 170.224 151.766 163.438 1.00 37.40  ? 768  PHE A C   1 
ATOM   4977 O  O   . PHE A 1 768 ? 170.383 152.265 164.559 1.00 37.40  ? 768  PHE A O   1 
ATOM   4978 C  CB  . PHE A 1 768 ? 170.729 153.059 161.364 1.00 37.40  ? 768  PHE A CB  1 
ATOM   4979 C  CG  . PHE A 1 768 ? 170.513 154.404 161.994 1.00 37.40  ? 768  PHE A CG  1 
ATOM   4980 C  CD1 . PHE A 1 768 ? 169.269 154.766 162.478 1.00 37.40  ? 768  PHE A CD1 1 
ATOM   4981 C  CD2 . PHE A 1 768 ? 171.554 155.301 162.110 1.00 37.40  ? 768  PHE A CD2 1 
ATOM   4982 C  CE1 . PHE A 1 768 ? 169.071 156.002 163.055 1.00 37.40  ? 768  PHE A CE1 1 
ATOM   4983 C  CE2 . PHE A 1 768 ? 171.359 156.536 162.690 1.00 37.40  ? 768  PHE A CE2 1 
ATOM   4984 C  CZ  . PHE A 1 768 ? 170.117 156.886 163.163 1.00 37.40  ? 768  PHE A CZ  1 
ATOM   4985 N  N   . MET A 1 769 ? 169.173 151.002 163.135 1.00 34.56  ? 769  MET A N   1 
ATOM   4986 C  CA  . MET A 1 769 ? 168.194 150.658 164.156 1.00 34.56  ? 769  MET A CA  1 
ATOM   4987 C  C   . MET A 1 769 ? 168.841 149.884 165.294 1.00 34.56  ? 769  MET A C   1 
ATOM   4988 O  O   . MET A 1 769 ? 168.622 150.197 166.469 1.00 34.56  ? 769  MET A O   1 
ATOM   4989 C  CB  . MET A 1 769 ? 167.057 149.855 163.532 1.00 34.56  ? 769  MET A CB  1 
ATOM   4990 C  CG  . MET A 1 769 ? 165.929 150.707 162.994 1.00 34.56  ? 769  MET A CG  1 
ATOM   4991 S  SD  . MET A 1 769 ? 164.449 149.742 162.678 1.00 34.56  ? 769  MET A SD  1 
ATOM   4992 C  CE  . MET A 1 769 ? 165.180 148.304 161.923 1.00 34.56  ? 769  MET A CE  1 
ATOM   4993 N  N   . ILE A 1 770 ? 169.667 148.892 164.963 1.00 36.31  ? 770  ILE A N   1 
ATOM   4994 C  CA  . ILE A 1 770 ? 170.288 148.059 165.990 1.00 36.31  ? 770  ILE A CA  1 
ATOM   4995 C  C   . ILE A 1 770 ? 171.199 148.894 166.881 1.00 36.31  ? 770  ILE A C   1 
ATOM   4996 O  O   . ILE A 1 770 ? 171.282 148.671 168.095 1.00 36.31  ? 770  ILE A O   1 
ATOM   4997 C  CB  . ILE A 1 770 ? 171.046 146.890 165.337 1.00 36.31  ? 770  ILE A CB  1 
ATOM   4998 C  CG1 . ILE A 1 770 ? 170.066 145.926 164.681 1.00 36.31  ? 770  ILE A CG1 1 
ATOM   4999 C  CG2 . ILE A 1 770 ? 171.865 146.146 166.362 1.00 36.31  ? 770  ILE A CG2 1 
ATOM   5000 C  CD1 . ILE A 1 770 ? 169.076 145.327 165.635 1.00 36.31  ? 770  ILE A CD1 1 
ATOM   5001 N  N   . PHE A 1 771 ? 171.904 149.863 166.299 1.00 37.05  ? 771  PHE A N   1 
ATOM   5002 C  CA  . PHE A 1 771 ? 172.770 150.716 167.104 1.00 37.05  ? 771  PHE A CA  1 
ATOM   5003 C  C   . PHE A 1 771 ? 171.975 151.677 167.981 1.00 37.05  ? 771  PHE A C   1 
ATOM   5004 O  O   . PHE A 1 771 ? 172.255 151.795 169.177 1.00 37.05  ? 771  PHE A O   1 
ATOM   5005 C  CB  . PHE A 1 771 ? 173.721 151.498 166.201 1.00 37.05  ? 771  PHE A CB  1 
ATOM   5006 C  CG  . PHE A 1 771 ? 174.783 152.257 166.944 1.00 37.05  ? 771  PHE A CG  1 
ATOM   5007 C  CD1 . PHE A 1 771 ? 175.129 151.920 168.239 1.00 37.05  ? 771  PHE A CD1 1 
ATOM   5008 C  CD2 . PHE A 1 771 ? 175.428 153.321 166.344 1.00 37.05  ? 771  PHE A CD2 1 
ATOM   5009 C  CE1 . PHE A 1 771 ? 176.101 152.625 168.919 1.00 37.05  ? 771  PHE A CE1 1 
ATOM   5010 C  CE2 . PHE A 1 771 ? 176.401 154.026 167.018 1.00 37.05  ? 771  PHE A CE2 1 
ATOM   5011 C  CZ  . PHE A 1 771 ? 176.736 153.677 168.306 1.00 37.05  ? 771  PHE A CZ  1 
ATOM   5012 N  N   . PHE A 1 772 ? 170.988 152.370 167.418 1.00 35.08  ? 772  PHE A N   1 
ATOM   5013 C  CA  . PHE A 1 772 ? 170.373 153.499 168.104 1.00 35.08  ? 772  PHE A CA  1 
ATOM   5014 C  C   . PHE A 1 772 ? 169.082 153.153 168.836 1.00 35.08  ? 772  PHE A C   1 
ATOM   5015 O  O   . PHE A 1 772 ? 168.456 154.052 169.404 1.00 35.08  ? 772  PHE A O   1 
ATOM   5016 C  CB  . PHE A 1 772 ? 170.114 154.633 167.113 1.00 35.08  ? 772  PHE A CB  1 
ATOM   5017 C  CG  . PHE A 1 772 ? 171.268 155.578 166.961 1.00 35.08  ? 772  PHE A CG  1 
ATOM   5018 C  CD1 . PHE A 1 772 ? 171.398 156.672 167.795 1.00 35.08  ? 772  PHE A CD1 1 
ATOM   5019 C  CD2 . PHE A 1 772 ? 172.222 155.373 165.984 1.00 35.08  ? 772  PHE A CD2 1 
ATOM   5020 C  CE1 . PHE A 1 772 ? 172.459 157.544 167.654 1.00 35.08  ? 772  PHE A CE1 1 
ATOM   5021 C  CE2 . PHE A 1 772 ? 173.283 156.240 165.840 1.00 35.08  ? 772  PHE A CE2 1 
ATOM   5022 C  CZ  . PHE A 1 772 ? 173.401 157.327 166.677 1.00 35.08  ? 772  PHE A CZ  1 
ATOM   5023 N  N   . GLY A 1 773 ? 168.663 151.892 168.843 1.00 33.63  ? 773  GLY A N   1 
ATOM   5024 C  CA  . GLY A 1 773 ? 167.525 151.491 169.634 1.00 33.63  ? 773  GLY A CA  1 
ATOM   5025 C  C   . GLY A 1 773 ? 167.855 151.304 171.102 1.00 33.63  ? 773  GLY A C   1 
ATOM   5026 O  O   . GLY A 1 773 ? 167.262 151.938 171.982 1.00 33.63  ? 773  GLY A O   1 
ATOM   5027 N  N   . PRO A 1 774 ? 168.807 150.415 171.397 1.00 35.94  ? 774  PRO A N   1 
ATOM   5028 C  CA  . PRO A 1 774 ? 169.147 150.145 172.801 1.00 35.94  ? 774  PRO A CA  1 
ATOM   5029 C  C   . PRO A 1 774 ? 169.578 151.369 173.589 1.00 35.94  ? 774  PRO A C   1 
ATOM   5030 O  O   . PRO A 1 774 ? 169.392 151.386 174.812 1.00 35.94  ? 774  PRO A O   1 
ATOM   5031 C  CB  . PRO A 1 774 ? 170.282 149.124 172.686 1.00 35.94  ? 774  PRO A CB  1 
ATOM   5032 C  CG  . PRO A 1 774 ? 169.968 148.395 171.434 1.00 35.94  ? 774  PRO A CG  1 
ATOM   5033 C  CD  . PRO A 1 774 ? 169.406 149.419 170.494 1.00 35.94  ? 774  PRO A CD  1 
ATOM   5034 N  N   . ILE A 1 775 ? 170.140 152.393 172.946 1.00 34.78  ? 775  ILE A N   1 
ATOM   5035 C  CA  . ILE A 1 775 ? 170.454 153.618 173.676 1.00 34.78  ? 775  ILE A CA  1 
ATOM   5036 C  C   . ILE A 1 775 ? 169.184 154.227 174.254 1.00 34.78  ? 775  ILE A C   1 
ATOM   5037 O  O   . ILE A 1 775 ? 169.155 154.654 175.414 1.00 34.78  ? 775  ILE A O   1 
ATOM   5038 C  CB  . ILE A 1 775 ? 171.202 154.612 172.772 1.00 34.78  ? 775  ILE A CB  1 
ATOM   5039 C  CG1 . ILE A 1 775 ? 172.507 153.999 172.271 1.00 34.78  ? 775  ILE A CG1 1 
ATOM   5040 C  CG2 . ILE A 1 775 ? 171.479 155.900 173.512 1.00 34.78  ? 775  ILE A CG2 1 
ATOM   5041 C  CD1 . ILE A 1 775 ? 173.302 154.926 171.394 1.00 34.78  ? 775  ILE A CD1 1 
ATOM   5042 N  N   . SER A 1 776 ? 168.114 154.270 173.461 1.00 35.74  ? 776  SER A N   1 
ATOM   5043 C  CA  . SER A 1 776 ? 166.828 154.720 173.982 1.00 35.74  ? 776  SER A CA  1 
ATOM   5044 C  C   . SER A 1 776 ? 166.280 153.744 175.015 1.00 35.74  ? 776  SER A C   1 
ATOM   5045 O  O   . SER A 1 776 ? 165.700 154.159 176.028 1.00 35.74  ? 776  SER A O   1 
ATOM   5046 C  CB  . SER A 1 776 ? 165.833 154.895 172.837 1.00 35.74  ? 776  SER A CB  1 
ATOM   5047 O  OG  . SER A 1 776 ? 166.170 156.008 172.033 1.00 35.74  ? 776  SER A OG  1 
ATOM   5048 N  N   . SER A 1 777 ? 166.446 152.443 174.765 1.00 35.90  ? 777  SER A N   1 
ATOM   5049 C  CA  . SER A 1 777 ? 165.892 151.438 175.665 1.00 35.90  ? 777  SER A CA  1 
ATOM   5050 C  C   . SER A 1 777 ? 166.499 151.527 177.056 1.00 35.90  ? 777  SER A C   1 
ATOM   5051 O  O   . SER A 1 777 ? 165.823 151.227 178.043 1.00 35.90  ? 777  SER A O   1 
ATOM   5052 C  CB  . SER A 1 777 ? 166.106 150.042 175.088 1.00 35.90  ? 777  SER A CB  1 
ATOM   5053 O  OG  . SER A 1 777 ? 164.970 149.618 174.359 1.00 35.90  ? 777  SER A OG  1 
ATOM   5054 N  N   . ILE A 1 778 ? 167.764 151.933 177.157 1.00 38.36  ? 778  ILE A N   1 
ATOM   5055 C  CA  . ILE A 1 778 ? 168.400 152.064 178.466 1.00 38.36  ? 778  ILE A CA  1 
ATOM   5056 C  C   . ILE A 1 778 ? 167.667 153.099 179.311 1.00 38.36  ? 778  ILE A C   1 
ATOM   5057 O  O   . ILE A 1 778 ? 167.305 152.848 180.469 1.00 38.36  ? 778  ILE A O   1 
ATOM   5058 C  CB  . ILE A 1 778 ? 169.887 152.423 178.301 1.00 38.36  ? 778  ILE A CB  1 
ATOM   5059 C  CG1 . ILE A 1 778 ? 170.691 151.188 177.903 1.00 38.36  ? 778  ILE A CG1 1 
ATOM   5060 C  CG2 . ILE A 1 778 ? 170.435 153.025 179.578 1.00 38.36  ? 778  ILE A CG2 1 
ATOM   5061 C  CD1 . ILE A 1 778 ? 172.112 151.494 177.513 1.00 38.36  ? 778  ILE A CD1 1 
ATOM   5062 N  N   . PHE A 1 779 ? 167.414 154.274 178.736 1.00 37.03  ? 779  PHE A N   1 
ATOM   5063 C  CA  . PHE A 1 779 ? 166.742 155.317 179.500 1.00 37.03  ? 779  PHE A CA  1 
ATOM   5064 C  C   . PHE A 1 779 ? 165.270 154.995 179.706 1.00 37.03  ? 779  PHE A C   1 
ATOM   5065 O  O   . PHE A 1 779 ? 164.676 155.417 180.703 1.00 37.03  ? 779  PHE A O   1 
ATOM   5066 C  CB  . PHE A 1 779 ? 166.918 156.665 178.812 1.00 37.03  ? 779  PHE A CB  1 
ATOM   5067 C  CG  . PHE A 1 779 ? 168.311 157.200 178.906 1.00 37.03  ? 779  PHE A CG  1 
ATOM   5068 C  CD1 . PHE A 1 779 ? 169.300 156.741 178.057 1.00 37.03  ? 779  PHE A CD1 1 
ATOM   5069 C  CD2 . PHE A 1 779 ? 168.641 158.143 179.858 1.00 37.03  ? 779  PHE A CD2 1 
ATOM   5070 C  CE1 . PHE A 1 779 ? 170.585 157.226 178.144 1.00 37.03  ? 779  PHE A CE1 1 
ATOM   5071 C  CE2 . PHE A 1 779 ? 169.928 158.629 179.950 1.00 37.03  ? 779  PHE A CE2 1 
ATOM   5072 C  CZ  . PHE A 1 779 ? 170.900 158.169 179.092 1.00 37.03  ? 779  PHE A CZ  1 
ATOM   5073 N  N   . ASP A 1 780 ? 164.668 154.229 178.797 1.00 35.01  ? 780  ASP A N   1 
ATOM   5074 C  CA  . ASP A 1 780 ? 163.303 153.780 179.044 1.00 35.01  ? 780  ASP A CA  1 
ATOM   5075 C  C   . ASP A 1 780 ? 163.250 152.796 180.211 1.00 35.01  ? 780  ASP A C   1 
ATOM   5076 O  O   . ASP A 1 780 ? 162.295 152.804 180.996 1.00 35.01  ? 780  ASP A O   1 
ATOM   5077 C  CB  . ASP A 1 780 ? 162.722 153.169 177.775 1.00 35.01  ? 780  ASP A CB  1 
ATOM   5078 C  CG  . ASP A 1 780 ? 162.173 154.211 176.832 1.00 35.01  ? 780  ASP A CG  1 
ATOM   5079 O  OD1 . ASP A 1 780 ? 161.431 155.096 177.300 1.00 35.01  ? 780  ASP A OD1 1 
ATOM   5080 O  OD2 . ASP A 1 780 ? 162.487 154.153 175.626 1.00 35.01  ? 780  ASP A OD2 1 
ATOM   5081 N  N   . ILE A 1 781 ? 164.272 151.951 180.349 1.00 35.73  ? 781  ILE A N   1 
ATOM   5082 C  CA  . ILE A 1 781 ? 164.372 151.083 181.519 1.00 35.73  ? 781  ILE A CA  1 
ATOM   5083 C  C   . ILE A 1 781 ? 164.552 151.915 182.780 1.00 35.73  ? 781  ILE A C   1 
ATOM   5084 O  O   . ILE A 1 781 ? 163.988 151.604 183.837 1.00 35.73  ? 781  ILE A O   1 
ATOM   5085 C  CB  . ILE A 1 781 ? 165.521 150.076 181.338 1.00 35.73  ? 781  ILE A CB  1 
ATOM   5086 C  CG1 . ILE A 1 781 ? 165.075 148.897 180.478 1.00 35.73  ? 781  ILE A CG1 1 
ATOM   5087 C  CG2 . ILE A 1 781 ? 166.031 149.585 182.677 1.00 35.73  ? 781  ILE A CG2 1 
ATOM   5088 C  CD1 . ILE A 1 781 ? 166.207 147.965 180.133 1.00 35.73  ? 781  ILE A CD1 1 
ATOM   5089 N  N   . LEU A 1 782 ? 165.352 152.978 182.694 1.00 35.92  ? 782  LEU A N   1 
ATOM   5090 C  CA  . LEU A 1 782 ? 165.482 153.886 183.829 1.00 35.92  ? 782  LEU A CA  1 
ATOM   5091 C  C   . LEU A 1 782 ? 164.132 154.482 184.212 1.00 35.92  ? 782  LEU A C   1 
ATOM   5092 O  O   . LEU A 1 782 ? 163.812 154.604 185.399 1.00 35.92  ? 782  LEU A O   1 
ATOM   5093 C  CB  . LEU A 1 782 ? 166.485 154.993 183.512 1.00 35.92  ? 782  LEU A CB  1 
ATOM   5094 C  CG  . LEU A 1 782 ? 167.942 154.691 183.846 1.00 35.92  ? 782  LEU A CG  1 
ATOM   5095 C  CD1 . LEU A 1 782 ? 168.832 155.856 183.458 1.00 35.92  ? 782  LEU A CD1 1 
ATOM   5096 C  CD2 . LEU A 1 782 ? 168.078 154.384 185.322 1.00 35.92  ? 782  LEU A CD2 1 
ATOM   5097 N  N   . THR A 1 783 ? 163.328 154.861 183.218 1.00 32.73  ? 783  THR A N   1 
ATOM   5098 C  CA  . THR A 1 783 ? 161.995 155.389 183.501 1.00 32.73  ? 783  THR A CA  1 
ATOM   5099 C  C   . THR A 1 783 ? 161.106 154.334 184.152 1.00 32.73  ? 783  THR A C   1 
ATOM   5100 O  O   . THR A 1 783 ? 160.337 154.640 185.073 1.00 32.73  ? 783  THR A O   1 
ATOM   5101 C  CB  . THR A 1 783 ? 161.350 155.906 182.218 1.00 32.73  ? 783  THR A CB  1 
ATOM   5102 O  OG1 . THR A 1 783 ? 162.186 156.909 181.631 1.00 32.73  ? 783  THR A OG1 1 
ATOM   5103 C  CG2 . THR A 1 783 ? 159.992 156.506 182.518 1.00 32.73  ? 783  THR A CG2 1 
ATOM   5104 N  N   . PHE A 1 784 ? 161.184 153.091 183.671 1.00 34.81  ? 784  PHE A N   1 
ATOM   5105 C  CA  . PHE A 1 784 ? 160.435 152.004 184.298 1.00 34.81  ? 784  PHE A CA  1 
ATOM   5106 C  C   . PHE A 1 784 ? 160.801 151.869 185.768 1.00 34.81  ? 784  PHE A C   1 
ATOM   5107 O  O   . PHE A 1 784 ? 159.925 151.773 186.635 1.00 34.81  ? 784  PHE A O   1 
ATOM   5108 C  CB  . PHE A 1 784 ? 160.704 150.685 183.577 1.00 34.81  ? 784  PHE A CB  1 
ATOM   5109 C  CG  . PHE A 1 784 ? 160.160 150.623 182.186 1.00 34.81  ? 784  PHE A CG  1 
ATOM   5110 C  CD1 . PHE A 1 784 ? 158.946 151.197 181.878 1.00 34.81  ? 784  PHE A CD1 1 
ATOM   5111 C  CD2 . PHE A 1 784 ? 160.851 149.960 181.193 1.00 34.81  ? 784  PHE A CD2 1 
ATOM   5112 C  CE1 . PHE A 1 784 ? 158.440 151.128 180.603 1.00 34.81  ? 784  PHE A CE1 1 
ATOM   5113 C  CE2 . PHE A 1 784 ? 160.349 149.887 179.920 1.00 34.81  ? 784  PHE A CE2 1 
ATOM   5114 C  CZ  . PHE A 1 784 ? 159.143 150.472 179.623 1.00 34.81  ? 784  PHE A CZ  1 
ATOM   5115 N  N   . CYS A 1 785 ? 162.102 151.855 186.064 1.00 39.87  ? 785  CYS A N   1 
ATOM   5116 C  CA  . CYS A 1 785 ? 162.545 151.727 187.449 1.00 39.87  ? 785  CYS A CA  1 
ATOM   5117 C  C   . CYS A 1 785 ? 162.084 152.911 188.285 1.00 39.87  ? 785  CYS A C   1 
ATOM   5118 O  O   . CYS A 1 785 ? 161.675 152.744 189.439 1.00 39.87  ? 785  CYS A O   1 
ATOM   5119 C  CB  . CYS A 1 785 ? 164.066 151.593 187.507 1.00 39.87  ? 785  CYS A CB  1 
ATOM   5120 S  SG  . CYS A 1 785 ? 164.705 150.034 186.861 1.00 39.87  ? 785  CYS A SG  1 
ATOM   5121 N  N   . LEU A 1 786 ? 162.144 154.117 187.720 1.00 37.97  ? 786  LEU A N   1 
ATOM   5122 C  CA  . LEU A 1 786 ? 161.732 155.305 188.459 1.00 37.97  ? 786  LEU A CA  1 
ATOM   5123 C  C   . LEU A 1 786 ? 160.250 155.249 188.811 1.00 37.97  ? 786  LEU A C   1 
ATOM   5124 O  O   . LEU A 1 786 ? 159.858 155.581 189.935 1.00 37.97  ? 786  LEU A O   1 
ATOM   5125 C  CB  . LEU A 1 786 ? 162.067 156.551 187.641 1.00 37.97  ? 786  LEU A CB  1 
ATOM   5126 C  CG  . LEU A 1 786 ? 161.801 157.975 188.129 1.00 37.97  ? 786  LEU A CG  1 
ATOM   5127 C  CD1 . LEU A 1 786 ? 162.628 158.904 187.282 1.00 37.97  ? 786  LEU A CD1 1 
ATOM   5128 C  CD2 . LEU A 1 786 ? 160.346 158.370 188.006 1.00 37.97  ? 786  LEU A CD2 1 
ATOM   5129 N  N   . MET A 1 787 ? 159.409 154.843 187.861 1.00 39.58  ? 787  MET A N   1 
ATOM   5130 C  CA  . MET A 1 787 ? 157.995 154.642 188.171 1.00 39.58  ? 787  MET A CA  1 
ATOM   5131 C  C   . MET A 1 787 ? 157.769 153.537 189.193 1.00 39.58  ? 787  MET A C   1 
ATOM   5132 O  O   . MET A 1 787 ? 156.960 153.706 190.111 1.00 39.58  ? 787  MET A O   1 
ATOM   5133 C  CB  . MET A 1 787 ? 157.217 154.357 186.889 1.00 39.58  ? 787  MET A CB  1 
ATOM   5134 C  CG  . MET A 1 787 ? 156.770 155.597 186.178 1.00 39.58  ? 787  MET A CG  1 
ATOM   5135 S  SD  . MET A 1 787 ? 155.936 156.569 187.439 1.00 39.58  ? 787  MET A SD  1 
ATOM   5136 C  CE  . MET A 1 787 ? 156.545 158.194 187.092 1.00 39.58  ? 787  MET A CE  1 
ATOM   5137 N  N   . TRP A 1 788 ? 158.471 152.413 189.065 1.00 43.93  ? 788  TRP A N   1 
ATOM   5138 C  CA  . TRP A 1 788 ? 158.144 151.259 189.894 1.00 43.93  ? 788  TRP A CA  1 
ATOM   5139 C  C   . TRP A 1 788 ? 158.496 151.505 191.354 1.00 43.93  ? 788  TRP A C   1 
ATOM   5140 O  O   . TRP A 1 788 ? 157.766 151.081 192.257 1.00 43.93  ? 788  TRP A O   1 
ATOM   5141 C  CB  . TRP A 1 788 ? 158.858 150.017 189.368 1.00 43.93  ? 788  TRP A CB  1 
ATOM   5142 C  CG  . TRP A 1 788 ? 158.539 148.776 190.134 1.00 43.93  ? 788  TRP A CG  1 
ATOM   5143 C  CD1 . TRP A 1 788 ? 159.203 148.284 191.218 1.00 43.93  ? 788  TRP A CD1 1 
ATOM   5144 C  CD2 . TRP A 1 788 ? 157.458 147.873 189.879 1.00 43.93  ? 788  TRP A CD2 1 
ATOM   5145 N  NE1 . TRP A 1 788 ? 158.609 147.121 191.647 1.00 43.93  ? 788  TRP A NE1 1 
ATOM   5146 C  CE2 . TRP A 1 788 ? 157.534 146.849 190.842 1.00 43.93  ? 788  TRP A CE2 1 
ATOM   5147 C  CE3 . TRP A 1 788 ? 156.436 147.829 188.927 1.00 43.93  ? 788  TRP A CE3 1 
ATOM   5148 C  CZ2 . TRP A 1 788 ? 156.625 145.793 190.880 1.00 43.93  ? 788  TRP A CZ2 1 
ATOM   5149 C  CZ3 . TRP A 1 788 ? 155.536 146.781 188.966 1.00 43.93  ? 788  TRP A CZ3 1 
ATOM   5150 C  CH2 . TRP A 1 788 ? 155.636 145.778 189.935 1.00 43.93  ? 788  TRP A CH2 1 
ATOM   5151 N  N   . TRP A 1 789 ? 159.614 152.181 191.609 1.00 46.15  ? 789  TRP A N   1 
ATOM   5152 C  CA  . TRP A 1 789 ? 160.098 152.343 192.975 1.00 46.15  ? 789  TRP A CA  1 
ATOM   5153 C  C   . TRP A 1 789 ? 159.764 153.712 193.556 1.00 46.15  ? 789  TRP A C   1 
ATOM   5154 O  O   . TRP A 1 789 ? 159.167 153.799 194.633 1.00 46.15  ? 789  TRP A O   1 
ATOM   5155 C  CB  . TRP A 1 789 ? 161.610 152.103 193.024 1.00 46.15  ? 789  TRP A CB  1 
ATOM   5156 C  CG  . TRP A 1 789 ? 161.996 150.734 192.570 1.00 46.15  ? 789  TRP A CG  1 
ATOM   5157 C  CD1 . TRP A 1 789 ? 162.638 150.405 191.415 1.00 46.15  ? 789  TRP A CD1 1 
ATOM   5158 C  CD2 . TRP A 1 789 ? 161.749 149.504 193.256 1.00 46.15  ? 789  TRP A CD2 1 
ATOM   5159 N  NE1 . TRP A 1 789 ? 162.812 149.045 191.340 1.00 46.15  ? 789  TRP A NE1 1 
ATOM   5160 C  CE2 . TRP A 1 789 ? 162.274 148.469 192.459 1.00 46.15  ? 789  TRP A CE2 1 
ATOM   5161 C  CE3 . TRP A 1 789 ? 161.136 149.177 194.469 1.00 46.15  ? 789  TRP A CE3 1 
ATOM   5162 C  CZ2 . TRP A 1 789 ? 162.206 147.131 192.836 1.00 46.15  ? 789  TRP A CZ2 1 
ATOM   5163 C  CZ3 . TRP A 1 789 ? 161.070 147.848 194.841 1.00 46.15  ? 789  TRP A CZ3 1 
ATOM   5164 C  CH2 . TRP A 1 789 ? 161.601 146.841 194.027 1.00 46.15  ? 789  TRP A CH2 1 
ATOM   5165 N  N   . VAL A 1 790 ? 160.138 154.785 192.859 1.00 44.62  ? 790  VAL A N   1 
ATOM   5166 C  CA  . VAL A 1 790 ? 160.024 156.119 193.439 1.00 44.62  ? 790  VAL A CA  1 
ATOM   5167 C  C   . VAL A 1 790 ? 158.565 156.537 193.575 1.00 44.62  ? 790  VAL A C   1 
ATOM   5168 O  O   . VAL A 1 790 ? 158.169 157.128 194.587 1.00 44.62  ? 790  VAL A O   1 
ATOM   5169 C  CB  . VAL A 1 790 ? 160.827 157.132 192.607 1.00 44.62  ? 790  VAL A CB  1 
ATOM   5170 C  CG1 . VAL A 1 790 ? 160.696 158.519 193.201 1.00 44.62  ? 790  VAL A CG1 1 
ATOM   5171 C  CG2 . VAL A 1 790 ? 162.284 156.718 192.550 1.00 44.62  ? 790  VAL A CG2 1 
ATOM   5172 N  N   . PHE A 1 791 ? 157.743 156.245 192.571 1.00 43.72  ? 791  PHE A N   1 
ATOM   5173 C  CA  . PHE A 1 791 ? 156.358 156.698 192.563 1.00 43.72  ? 791  PHE A CA  1 
ATOM   5174 C  C   . PHE A 1 791 ? 155.363 155.607 192.934 1.00 43.72  ? 791  PHE A C   1 
ATOM   5175 O  O   . PHE A 1 791 ? 154.154 155.856 192.899 1.00 43.72  ? 791  PHE A O   1 
ATOM   5176 C  CB  . PHE A 1 791 ? 156.010 157.289 191.196 1.00 43.72  ? 791  PHE A CB  1 
ATOM   5177 C  CG  . PHE A 1 791 ? 156.646 158.623 190.943 1.00 43.72  ? 791  PHE A CG  1 
ATOM   5178 C  CD1 . PHE A 1 791 ? 158.012 158.731 190.757 1.00 43.72  ? 791  PHE A CD1 1 
ATOM   5179 C  CD2 . PHE A 1 791 ? 155.880 159.771 190.901 1.00 43.72  ? 791  PHE A CD2 1 
ATOM   5180 C  CE1 . PHE A 1 791 ? 158.597 159.956 190.533 1.00 43.72  ? 791  PHE A CE1 1 
ATOM   5181 C  CE2 . PHE A 1 791 ? 156.464 160.999 190.674 1.00 43.72  ? 791  PHE A CE2 1 
ATOM   5182 C  CZ  . PHE A 1 791 ? 157.823 161.091 190.489 1.00 43.72  ? 791  PHE A CZ  1 
ATOM   5183 N  N   . HIS A 1 792 ? 155.841 154.412 193.282 1.00 49.30  ? 792  HIS A N   1 
ATOM   5184 C  CA  . HIS A 1 792 ? 155.020 153.363 193.888 1.00 49.30  ? 792  HIS A CA  1 
ATOM   5185 C  C   . HIS A 1 792 ? 153.861 152.936 192.993 1.00 49.30  ? 792  HIS A C   1 
ATOM   5186 O  O   . HIS A 1 792 ? 152.807 152.524 193.482 1.00 49.30  ? 792  HIS A O   1 
ATOM   5187 C  CB  . HIS A 1 792 ? 154.502 153.800 195.260 1.00 49.30  ? 792  HIS A CB  1 
ATOM   5188 C  CG  . HIS A 1 792 ? 155.589 154.163 196.222 1.00 49.30  ? 792  HIS A CG  1 
ATOM   5189 N  ND1 . HIS A 1 792 ? 155.759 155.443 196.704 1.00 49.30  ? 792  HIS A ND1 1 
ATOM   5190 C  CD2 . HIS A 1 792 ? 156.570 153.417 196.781 1.00 49.30  ? 792  HIS A CD2 1 
ATOM   5191 C  CE1 . HIS A 1 792 ? 156.794 155.467 197.524 1.00 49.30  ? 792  HIS A CE1 1 
ATOM   5192 N  NE2 . HIS A 1 792 ? 157.304 154.251 197.588 1.00 49.30  ? 792  HIS A NE2 1 
ATOM   5193 N  N   . ALA A 1 793 ? 154.040 153.027 191.678 1.00 46.86  ? 793  ALA A N   1 
ATOM   5194 C  CA  . ALA A 1 793 ? 153.054 152.511 190.730 1.00 46.86  ? 793  ALA A CA  1 
ATOM   5195 C  C   . ALA A 1 793 ? 153.365 151.051 190.397 1.00 46.86  ? 793  ALA A C   1 
ATOM   5196 O  O   . ALA A 1 793 ? 153.539 150.660 189.246 1.00 46.86  ? 793  ALA A O   1 
ATOM   5197 C  CB  . ALA A 1 793 ? 153.019 153.375 189.476 1.00 46.86  ? 793  ALA A CB  1 
ATOM   5198 N  N   . ASN A 1 794 ? 153.435 150.240 191.453 1.00 47.74  ? 794  ASN A N   1 
ATOM   5199 C  CA  . ASN A 1 794 ? 153.839 148.844 191.352 1.00 47.74  ? 794  ASN A CA  1 
ATOM   5200 C  C   . ASN A 1 794 ? 152.669 147.883 191.522 1.00 47.74  ? 794  ASN A C   1 
ATOM   5201 O  O   . ASN A 1 794 ? 152.873 146.721 191.886 1.00 47.74  ? 794  ASN A O   1 
ATOM   5202 C  CB  . ASN A 1 794 ? 154.927 148.538 192.380 1.00 47.74  ? 794  ASN A CB  1 
ATOM   5203 C  CG  . ASN A 1 794 ? 154.626 149.135 193.739 1.00 47.74  ? 794  ASN A CG  1 
ATOM   5204 O  OD1 . ASN A 1 794 ? 153.624 149.826 193.917 1.00 47.74  ? 794  ASN A OD1 1 
ATOM   5205 N  ND2 . ASN A 1 794 ? 155.494 148.869 194.708 1.00 47.74  ? 794  ASN A ND2 1 
ATOM   5206 N  N   . THR A 1 795 ? 151.450 148.343 191.273 1.00 48.93  ? 795  THR A N   1 
ATOM   5207 C  CA  . THR A 1 795 ? 150.263 147.516 191.390 1.00 48.93  ? 795  THR A CA  1 
ATOM   5208 C  C   . THR A 1 795 ? 149.387 147.715 190.163 1.00 48.93  ? 795  THR A C   1 
ATOM   5209 O  O   . THR A 1 795 ? 149.202 148.846 189.707 1.00 48.93  ? 795  THR A O   1 
ATOM   5210 C  CB  . THR A 1 795 ? 149.472 147.867 192.660 1.00 48.93  ? 795  THR A CB  1 
ATOM   5211 O  OG1 . THR A 1 795 ? 150.337 147.784 193.799 1.00 48.93  ? 795  THR A OG1 1 
ATOM   5212 C  CG2 . THR A 1 795 ? 148.303 146.914 192.859 1.00 48.93  ? 795  THR A CG2 1 
ATOM   5213 N  N   . PRO A 1 796 ? 148.839 146.633 189.607 1.00 48.46  ? 796  PRO A N   1 
ATOM   5214 C  CA  . PRO A 1 796 ? 147.998 146.773 188.408 1.00 48.46  ? 796  PRO A CA  1 
ATOM   5215 C  C   . PRO A 1 796 ? 146.790 147.669 188.604 1.00 48.46  ? 796  PRO A C   1 
ATOM   5216 O  O   . PRO A 1 796 ? 146.202 148.113 187.611 1.00 48.46  ? 796  PRO A O   1 
ATOM   5217 C  CB  . PRO A 1 796 ? 147.579 145.330 188.110 1.00 48.46  ? 796  PRO A CB  1 
ATOM   5218 C  CG  . PRO A 1 796 ? 148.698 144.513 188.649 1.00 48.46  ? 796  PRO A CG  1 
ATOM   5219 C  CD  . PRO A 1 796 ? 149.159 145.225 189.891 1.00 48.46  ? 796  PRO A CD  1 
ATOM   5220 N  N   . GLU A 1 797 ? 146.392 147.944 189.847 1.00 51.73  ? 797  GLU A N   1 
ATOM   5221 C  CA  . GLU A 1 797 ? 145.289 148.870 190.071 1.00 51.73  ? 797  GLU A CA  1 
ATOM   5222 C  C   . GLU A 1 797 ? 145.707 150.313 189.822 1.00 51.73  ? 797  GLU A C   1 
ATOM   5223 O  O   . GLU A 1 797 ? 144.847 151.174 189.601 1.00 51.73  ? 797  GLU A O   1 
ATOM   5224 C  CB  . GLU A 1 797 ? 144.747 148.708 191.491 1.00 51.73  ? 797  GLU A CB  1 
ATOM   5225 C  CG  . GLU A 1 797 ? 144.502 147.263 191.901 1.00 51.73  ? 797  GLU A CG  1 
ATOM   5226 C  CD  . GLU A 1 797 ? 143.508 146.548 191.002 1.00 51.73  ? 797  GLU A CD  1 
ATOM   5227 O  OE1 . GLU A 1 797 ? 143.595 145.308 190.890 1.00 51.73  ? 797  GLU A OE1 1 
ATOM   5228 O  OE2 . GLU A 1 797 ? 142.631 147.221 190.419 1.00 51.73  ? 797  GLU A OE2 1 
ATOM   5229 N  N   . THR A 1 798 ? 147.008 150.600 189.851 1.00 44.09  ? 798  THR A N   1 
ATOM   5230 C  CA  . THR A 1 798 ? 147.523 151.939 189.591 1.00 44.09  ? 798  THR A CA  1 
ATOM   5231 C  C   . THR A 1 798 ? 148.452 151.969 188.379 1.00 44.09  ? 798  THR A C   1 
ATOM   5232 O  O   . THR A 1 798 ? 149.383 152.776 188.319 1.00 44.09  ? 798  THR A O   1 
ATOM   5233 C  CB  . THR A 1 798 ? 148.233 152.494 190.825 1.00 44.09  ? 798  THR A CB  1 
ATOM   5234 O  OG1 . THR A 1 798 ? 148.710 153.816 190.550 1.00 44.09  ? 798  THR A OG1 1 
ATOM   5235 C  CG2 . THR A 1 798 ? 149.400 151.605 191.226 1.00 44.09  ? 798  THR A CG2 1 
ATOM   5236 N  N   . GLN A 1 799 ? 148.199 151.100 187.398 1.00 36.73  ? 799  GLN A N   1 
ATOM   5237 C  CA  . GLN A 1 799 ? 149.026 151.053 186.198 1.00 36.73  ? 799  GLN A CA  1 
ATOM   5238 C  C   . GLN A 1 799 ? 148.928 152.324 185.370 1.00 36.73  ? 799  GLN A C   1 
ATOM   5239 O  O   . GLN A 1 799 ? 149.815 152.581 184.550 1.00 36.73  ? 799  GLN A O   1 
ATOM   5240 C  CB  . GLN A 1 799 ? 148.624 149.859 185.335 1.00 36.73  ? 799  GLN A CB  1 
ATOM   5241 C  CG  . GLN A 1 799 ? 147.149 149.848 184.975 1.00 36.73  ? 799  GLN A CG  1 
ATOM   5242 C  CD  . GLN A 1 799 ? 146.781 148.729 184.023 1.00 36.73  ? 799  GLN A CD  1 
ATOM   5243 O  OE1 . GLN A 1 799 ? 147.647 148.032 183.502 1.00 36.73  ? 799  GLN A OE1 1 
ATOM   5244 N  NE2 . GLN A 1 799 ? 145.487 148.552 183.794 1.00 36.73  ? 799  GLN A NE2 1 
ATOM   5245 N  N   . THR A 1 800 ? 147.864 153.109 185.547 1.00 34.67  ? 800  THR A N   1 
ATOM   5246 C  CA  . THR A 1 800 ? 147.665 154.284 184.706 1.00 34.67  ? 800  THR A CA  1 
ATOM   5247 C  C   . THR A 1 800 ? 148.752 155.326 184.934 1.00 34.67  ? 800  THR A C   1 
ATOM   5248 O  O   . THR A 1 800 ? 149.232 155.949 183.980 1.00 34.67  ? 800  THR A O   1 
ATOM   5249 C  CB  . THR A 1 800 ? 146.285 154.883 184.960 1.00 34.67  ? 800  THR A CB  1 
ATOM   5250 O  OG1 . THR A 1 800 ? 145.286 153.882 184.739 1.00 34.67  ? 800  THR A OG1 1 
ATOM   5251 C  CG2 . THR A 1 800 ? 146.034 156.046 184.023 1.00 34.67  ? 800  THR A CG2 1 
ATOM   5252 N  N   . LEU A 1 801 ? 149.148 155.538 186.191 1.00 33.46  ? 801  LEU A N   1 
ATOM   5253 C  CA  . LEU A 1 801 ? 150.217 156.492 186.465 1.00 33.46  ? 801  LEU A CA  1 
ATOM   5254 C  C   . LEU A 1 801 ? 151.517 156.058 185.806 1.00 33.46  ? 801  LEU A C   1 
ATOM   5255 O  O   . LEU A 1 801 ? 152.216 156.876 185.200 1.00 33.46  ? 801  LEU A O   1 
ATOM   5256 C  CB  . LEU A 1 801 ? 150.416 156.653 187.970 1.00 33.46  ? 801  LEU A CB  1 
ATOM   5257 C  CG  . LEU A 1 801 ? 151.534 157.617 188.366 1.00 33.46  ? 801  LEU A CG  1 
ATOM   5258 C  CD1 . LEU A 1 801 ? 151.314 158.969 187.720 1.00 33.46  ? 801  LEU A CD1 1 
ATOM   5259 C  CD2 . LEU A 1 801 ? 151.615 157.753 189.875 1.00 33.46  ? 801  LEU A CD2 1 
ATOM   5260 N  N   . PHE A 1 802 ? 151.827 154.773 185.907 1.00 34.04  ? 802  PHE A N   1 
ATOM   5261 C  CA  . PHE A 1 802 ? 153.032 154.234 185.300 1.00 34.04  ? 802  PHE A CA  1 
ATOM   5262 C  C   . PHE A 1 802 ? 152.906 154.317 183.791 1.00 34.04  ? 802  PHE A C   1 
ATOM   5263 O  O   . PHE A 1 802 ? 153.801 154.799 183.119 1.00 34.04  ? 802  PHE A O   1 
ATOM   5264 C  CB  . PHE A 1 802 ? 153.221 152.783 185.717 1.00 34.04  ? 802  PHE A CB  1 
ATOM   5265 C  CG  . PHE A 1 802 ? 154.459 152.145 185.172 1.00 34.04  ? 802  PHE A CG  1 
ATOM   5266 C  CD1 . PHE A 1 802 ? 155.371 151.567 186.020 1.00 34.04  ? 802  PHE A CD1 1 
ATOM   5267 C  CD2 . PHE A 1 802 ? 154.700 152.106 183.821 1.00 34.04  ? 802  PHE A CD2 1 
ATOM   5268 C  CE1 . PHE A 1 802 ? 156.509 150.968 185.530 1.00 34.04  ? 802  PHE A CE1 1 
ATOM   5269 C  CE2 . PHE A 1 802 ? 155.835 151.514 183.321 1.00 34.04  ? 802  PHE A CE2 1 
ATOM   5270 C  CZ  . PHE A 1 802 ? 156.744 150.942 184.177 1.00 34.04  ? 802  PHE A CZ  1 
ATOM   5271 N  N   . GLN A 1 803 ? 151.788 153.849 183.254 1.00 31.01  ? 803  GLN A N   1 
ATOM   5272 C  CA  . GLN A 1 803 ? 151.590 153.878 181.816 1.00 31.01  ? 803  GLN A CA  1 
ATOM   5273 C  C   . GLN A 1 803 ? 151.592 155.303 181.321 1.00 31.01  ? 803  GLN A C   1 
ATOM   5274 O  O   . GLN A 1 803 ? 152.182 155.598 180.304 1.00 31.01  ? 803  GLN A O   1 
ATOM   5275 C  CB  . GLN A 1 803 ? 150.265 153.227 181.451 1.00 31.01  ? 803  GLN A CB  1 
ATOM   5276 C  CG  . GLN A 1 803 ? 150.283 151.714 181.479 1.00 31.01  ? 803  GLN A CG  1 
ATOM   5277 C  CD  . GLN A 1 803 ? 148.898 151.136 181.648 1.00 31.01  ? 803  GLN A CD  1 
ATOM   5278 O  OE1 . GLN A 1 803 ? 148.293 151.261 182.709 1.00 31.01  ? 803  GLN A OE1 1 
ATOM   5279 N  NE2 . GLN A 1 803 ? 148.390 150.496 180.608 1.00 31.01  ? 803  GLN A NE2 1 
ATOM   5280 N  N   . SER A 1 804 ? 150.923 156.193 182.037 1.00 28.66  ? 804  SER A N   1 
ATOM   5281 C  CA  . SER A 1 804 ? 150.888 157.596 181.658 1.00 28.66  ? 804  SER A CA  1 
ATOM   5282 C  C   . SER A 1 804 ? 152.262 158.206 181.767 1.00 28.66  ? 804  SER A C   1 
ATOM   5283 O  O   . SER A 1 804 ? 152.649 159.031 180.962 1.00 28.66  ? 804  SER A O   1 
ATOM   5284 C  CB  . SER A 1 804 ? 149.944 158.374 182.555 1.00 28.66  ? 804  SER A CB  1 
ATOM   5285 O  OG  . SER A 1 804 ? 150.607 158.748 183.743 1.00 28.66  ? 804  SER A OG  1 
ATOM   5286 N  N   . GLY A 1 805 ? 152.980 157.826 182.810 1.00 28.15  ? 805  GLY A N   1 
ATOM   5287 C  CA  . GLY A 1 805 ? 154.306 158.345 183.047 1.00 28.15  ? 805  GLY A CA  1 
ATOM   5288 C  C   . GLY A 1 805 ? 155.329 158.016 181.989 1.00 28.15  ? 805  GLY A C   1 
ATOM   5289 O  O   . GLY A 1 805 ? 156.124 158.862 181.634 1.00 28.15  ? 805  GLY A O   1 
ATOM   5290 N  N   . TRP A 1 806 ? 155.329 156.797 181.478 1.00 23.83  ? 806  TRP A N   1 
ATOM   5291 C  CA  . TRP A 1 806 ? 156.317 156.472 180.468 1.00 23.83  ? 806  TRP A CA  1 
ATOM   5292 C  C   . TRP A 1 806 ? 155.942 157.106 179.155 1.00 23.83  ? 806  TRP A C   1 
ATOM   5293 O  O   . TRP A 1 806 ? 156.784 157.269 178.293 1.00 23.83  ? 806  TRP A O   1 
ATOM   5294 C  CB  . TRP A 1 806 ? 156.503 154.967 180.292 1.00 23.83  ? 806  TRP A CB  1 
ATOM   5295 C  CG  . TRP A 1 806 ? 157.479 154.634 179.208 1.00 23.83  ? 806  TRP A CG  1 
ATOM   5296 C  CD1 . TRP A 1 806 ? 158.650 155.262 178.955 1.00 23.83  ? 806  TRP A CD1 1 
ATOM   5297 C  CD2 . TRP A 1 806 ? 157.371 153.587 178.239 1.00 23.83  ? 806  TRP A CD2 1 
ATOM   5298 N  NE1 . TRP A 1 806 ? 159.281 154.681 177.886 1.00 23.83  ? 806  TRP A NE1 1 
ATOM   5299 C  CE2 . TRP A 1 806 ? 158.510 153.649 177.429 1.00 23.83  ? 806  TRP A CE2 1 
ATOM   5300 C  CE3 . TRP A 1 806 ? 156.418 152.609 177.975 1.00 23.83  ? 806  TRP A CE3 1 
ATOM   5301 C  CZ2 . TRP A 1 806 ? 158.722 152.777 176.382 1.00 23.83  ? 806  TRP A CZ2 1 
ATOM   5302 C  CZ3 . TRP A 1 806 ? 156.634 151.745 176.931 1.00 23.83  ? 806  TRP A CZ3 1 
ATOM   5303 C  CH2 . TRP A 1 806 ? 157.772 151.833 176.149 1.00 23.83  ? 806  TRP A CH2 1 
ATOM   5304 N  N   . PHE A 1 807 ? 154.678 157.475 179.005 1.00 20.07  ? 807  PHE A N   1 
ATOM   5305 C  CA  . PHE A 1 807 ? 154.228 158.096 177.764 1.00 20.07  ? 807  PHE A CA  1 
ATOM   5306 C  C   . PHE A 1 807 ? 154.823 159.482 177.587 1.00 20.07  ? 807  PHE A C   1 
ATOM   5307 O  O   . PHE A 1 807 ? 155.269 159.834 176.491 1.00 20.07  ? 807  PHE A O   1 
ATOM   5308 C  CB  . PHE A 1 807 ? 152.701 158.160 177.741 1.00 20.07  ? 807  PHE A CB  1 
ATOM   5309 C  CG  . PHE A 1 807 ? 152.135 159.087 176.701 1.00 20.07  ? 807  PHE A CG  1 
ATOM   5310 C  CD1 . PHE A 1 807 ? 151.947 160.429 176.970 1.00 20.07  ? 807  PHE A CD1 1 
ATOM   5311 C  CD2 . PHE A 1 807 ? 151.768 158.607 175.462 1.00 20.07  ? 807  PHE A CD2 1 
ATOM   5312 C  CE1 . PHE A 1 807 ? 151.425 161.269 176.020 1.00 20.07  ? 807  PHE A CE1 1 
ATOM   5313 C  CE2 . PHE A 1 807 ? 151.241 159.445 174.513 1.00 20.07  ? 807  PHE A CE2 1 
ATOM   5314 C  CZ  . PHE A 1 807 ? 151.070 160.777 174.792 1.00 20.07  ? 807  PHE A CZ  1 
ATOM   5315 N  N   . VAL A 1 808 ? 154.826 160.289 178.646 1.00 22.02  ? 808  VAL A N   1 
ATOM   5316 C  CA  . VAL A 1 808 ? 155.316 161.657 178.498 1.00 22.02  ? 808  VAL A CA  1 
ATOM   5317 C  C   . VAL A 1 808 ? 156.788 161.657 178.099 1.00 22.02  ? 808  VAL A C   1 
ATOM   5318 O  O   . VAL A 1 808 ? 157.189 162.349 177.155 1.00 22.02  ? 808  VAL A O   1 
ATOM   5319 C  CB  . VAL A 1 808 ? 155.075 162.462 179.784 1.00 22.02  ? 808  VAL A CB  1 
ATOM   5320 C  CG1 . VAL A 1 808 ? 155.649 163.847 179.636 1.00 22.02  ? 808  VAL A CG1 1 
ATOM   5321 C  CG2 . VAL A 1 808 ? 153.595 162.536 180.087 1.00 22.02  ? 808  VAL A CG2 1 
ATOM   5322 N  N   . VAL A 1 809 ? 157.609 160.859 178.786 1.00 21.17  ? 809  VAL A N   1 
ATOM   5323 C  CA  . VAL A 1 809 ? 159.036 160.810 178.474 1.00 21.17  ? 809  VAL A CA  1 
ATOM   5324 C  C   . VAL A 1 809 ? 159.277 160.184 177.108 1.00 21.17  ? 809  VAL A C   1 
ATOM   5325 O  O   . VAL A 1 809 ? 160.147 160.635 176.354 1.00 21.17  ? 809  VAL A O   1 
ATOM   5326 C  CB  . VAL A 1 809 ? 159.808 160.074 179.581 1.00 21.17  ? 809  VAL A CB  1 
ATOM   5327 C  CG1 . VAL A 1 809 ? 161.129 159.567 179.056 1.00 21.17  ? 809  VAL A CG1 1 
ATOM   5328 C  CG2 . VAL A 1 809 ? 160.087 161.026 180.709 1.00 21.17  ? 809  VAL A CG2 1 
ATOM   5329 N  N   . GLY A 1 810 ? 158.527 159.141 176.759 1.00 20.61  ? 810  GLY A N   1 
ATOM   5330 C  CA  . GLY A 1 810 ? 158.704 158.539 175.453 1.00 20.61  ? 810  GLY A CA  1 
ATOM   5331 C  C   . GLY A 1 810 ? 158.394 159.505 174.329 1.00 20.61  ? 810  GLY A C   1 
ATOM   5332 O  O   . GLY A 1 810 ? 159.116 159.565 173.333 1.00 20.61  ? 810  GLY A O   1 
ATOM   5333 N  N   . LEU A 1 811 ? 157.318 160.275 174.470 1.00 19.59  ? 811  LEU A N   1 
ATOM   5334 C  CA  . LEU A 1 811 ? 156.958 161.233 173.437 1.00 19.59  ? 811  LEU A CA  1 
ATOM   5335 C  C   . LEU A 1 811 ? 157.898 162.426 173.396 1.00 19.59  ? 811  LEU A C   1 
ATOM   5336 O  O   . LEU A 1 811 ? 158.116 162.987 172.319 1.00 19.59  ? 811  LEU A O   1 
ATOM   5337 C  CB  . LEU A 1 811 ? 155.525 161.714 173.645 1.00 19.59  ? 811  LEU A CB  1 
ATOM   5338 C  CG  . LEU A 1 811 ? 155.024 162.804 172.706 1.00 19.59  ? 811  LEU A CG  1 
ATOM   5339 C  CD1 . LEU A 1 811 ? 155.133 162.341 171.272 1.00 19.59  ? 811  LEU A CD1 1 
ATOM   5340 C  CD2 . LEU A 1 811 ? 153.596 163.133 173.042 1.00 19.59  ? 811  LEU A CD2 1 
ATOM   5341 N  N   . LEU A 1 812 ? 158.463 162.826 174.535 1.00 19.77  ? 812  LEU A N   1 
ATOM   5342 C  CA  . LEU A 1 812 ? 159.400 163.942 174.511 1.00 19.77  ? 812  LEU A CA  1 
ATOM   5343 C  C   . LEU A 1 812 ? 160.751 163.534 173.936 1.00 19.77  ? 812  LEU A C   1 
ATOM   5344 O  O   . LEU A 1 812 ? 161.316 164.255 173.105 1.00 19.77  ? 812  LEU A O   1 
ATOM   5345 C  CB  . LEU A 1 812 ? 159.572 164.511 175.915 1.00 19.77  ? 812  LEU A CB  1 
ATOM   5346 C  CG  . LEU A 1 812 ? 158.795 165.798 176.152 1.00 19.77  ? 812  LEU A CG  1 
ATOM   5347 C  CD1 . LEU A 1 812 ? 157.341 165.469 176.403 1.00 19.77  ? 812  LEU A CD1 1 
ATOM   5348 C  CD2 . LEU A 1 812 ? 159.376 166.566 177.313 1.00 19.77  ? 812  LEU A CD2 1 
ATOM   5349 N  N   . SER A 1 813 ? 161.278 162.381 174.353 1.00 21.32  ? 813  SER A N   1 
ATOM   5350 C  CA  . SER A 1 813 ? 162.609 161.979 173.917 1.00 21.32  ? 813  SER A CA  1 
ATOM   5351 C  C   . SER A 1 813 ? 162.630 161.660 172.432 1.00 21.32  ? 813  SER A C   1 
ATOM   5352 O  O   . SER A 1 813 ? 163.628 161.914 171.751 1.00 21.32  ? 813  SER A O   1 
ATOM   5353 C  CB  . SER A 1 813 ? 163.086 160.778 174.726 1.00 21.32  ? 813  SER A CB  1 
ATOM   5354 O  OG  . SER A 1 813 ? 162.679 159.569 174.117 1.00 21.32  ? 813  SER A OG  1 
ATOM   5355 N  N   . GLN A 1 814 ? 161.539 161.101 171.910 1.00 20.91  ? 814  GLN A N   1 
ATOM   5356 C  CA  . GLN A 1 814 ? 161.491 160.782 170.489 1.00 20.91  ? 814  GLN A CA  1 
ATOM   5357 C  C   . GLN A 1 814 ? 161.677 162.028 169.638 1.00 20.91  ? 814  GLN A C   1 
ATOM   5358 O  O   . GLN A 1 814 ? 162.435 162.014 168.664 1.00 20.91  ? 814  GLN A O   1 
ATOM   5359 C  CB  . GLN A 1 814 ? 160.167 160.106 170.149 1.00 20.91  ? 814  GLN A CB  1 
ATOM   5360 C  CG  . GLN A 1 814 ? 160.253 158.612 170.019 1.00 20.91  ? 814  GLN A CG  1 
ATOM   5361 C  CD  . GLN A 1 814 ? 159.162 158.065 169.143 1.00 20.91  ? 814  GLN A CD  1 
ATOM   5362 O  OE1 . GLN A 1 814 ? 159.414 157.285 168.229 1.00 20.91  ? 814  GLN A OE1 1 
ATOM   5363 N  NE2 . GLN A 1 814 ? 157.935 158.482 169.407 1.00 20.91  ? 814  GLN A NE2 1 
ATOM   5364 N  N   . THR A 1 815 ? 160.994 163.118 169.990 1.00 20.49  ? 815  THR A N   1 
ATOM   5365 C  CA  . THR A 1 815 ? 161.117 164.340 169.206 1.00 20.49  ? 815  THR A CA  1 
ATOM   5366 C  C   . THR A 1 815 ? 162.411 165.077 169.523 1.00 20.49  ? 815  THR A C   1 
ATOM   5367 O  O   . THR A 1 815 ? 162.951 165.786 168.668 1.00 20.49  ? 815  THR A O   1 
ATOM   5368 C  CB  . THR A 1 815 ? 159.912 165.244 169.446 1.00 20.49  ? 815  THR A CB  1 
ATOM   5369 O  OG1 . THR A 1 815 ? 159.657 165.334 170.850 1.00 20.49  ? 815  THR A OG1 1 
ATOM   5370 C  CG2 . THR A 1 815 ? 158.690 164.683 168.759 1.00 20.49  ? 815  THR A CG2 1 
ATOM   5371 N  N   . LEU A 1 816 ? 162.925 164.931 170.745 1.00 22.06  ? 816  LEU A N   1 
ATOM   5372 C  CA  . LEU A 1 816 ? 164.152 165.636 171.098 1.00 22.06  ? 816  LEU A CA  1 
ATOM   5373 C  C   . LEU A 1 816 ? 165.391 164.976 170.511 1.00 22.06  ? 816  LEU A C   1 
ATOM   5374 O  O   . LEU A 1 816 ? 166.406 165.647 170.307 1.00 22.06  ? 816  LEU A O   1 
ATOM   5375 C  CB  . LEU A 1 816 ? 164.270 165.745 172.615 1.00 22.06  ? 816  LEU A CB  1 
ATOM   5376 C  CG  . LEU A 1 816 ? 163.379 166.826 173.216 1.00 22.06  ? 816  LEU A CG  1 
ATOM   5377 C  CD1 . LEU A 1 816 ? 163.938 167.337 174.527 1.00 22.06  ? 816  LEU A CD1 1 
ATOM   5378 C  CD2 . LEU A 1 816 ? 163.274 167.956 172.223 1.00 22.06  ? 816  LEU A CD2 1 
ATOM   5379 N  N   . ILE A 1 817 ? 165.338 163.672 170.240 1.00 24.34  ? 817  ILE A N   1 
ATOM   5380 C  CA  . ILE A 1 817 ? 166.508 162.985 169.717 1.00 24.34  ? 817  ILE A CA  1 
ATOM   5381 C  C   . ILE A 1 817 ? 166.742 163.311 168.252 1.00 24.34  ? 817  ILE A C   1 
ATOM   5382 O  O   . ILE A 1 817 ? 167.802 162.980 167.703 1.00 24.34  ? 817  ILE A O   1 
ATOM   5383 C  CB  . ILE A 1 817 ? 166.358 161.470 169.918 1.00 24.34  ? 817  ILE A CB  1 
ATOM   5384 C  CG1 . ILE A 1 817 ? 167.731 160.831 170.015 1.00 24.34  ? 817  ILE A CG1 1 
ATOM   5385 C  CG2 . ILE A 1 817 ? 165.565 160.855 168.781 1.00 24.34  ? 817  ILE A CG2 1 
ATOM   5386 C  CD1 . ILE A 1 817 ? 168.518 161.393 171.131 1.00 24.34  ? 817  ILE A CD1 1 
ATOM   5387 N  N   . VAL A 1 818 ? 165.768 163.947 167.600 1.00 24.87  ? 818  VAL A N   1 
ATOM   5388 C  CA  . VAL A 1 818 ? 165.904 164.286 166.189 1.00 24.87  ? 818  VAL A CA  1 
ATOM   5389 C  C   . VAL A 1 818 ? 167.084 165.224 165.980 1.00 24.87  ? 818  VAL A C   1 
ATOM   5390 O  O   . VAL A 1 818 ? 167.901 165.025 165.075 1.00 24.87  ? 818  VAL A O   1 
ATOM   5391 C  CB  . VAL A 1 818 ? 164.592 164.897 165.670 1.00 24.87  ? 818  VAL A CB  1 
ATOM   5392 C  CG1 . VAL A 1 818 ? 164.831 165.664 164.390 1.00 24.87  ? 818  VAL A CG1 1 
ATOM   5393 C  CG2 . VAL A 1 818 ? 163.560 163.812 165.462 1.00 24.87  ? 818  VAL A CG2 1 
ATOM   5394 N  N   . HIS A 1 819 ? 167.205 166.248 166.822 1.00 29.35  ? 819  HIS A N   1 
ATOM   5395 C  CA  . HIS A 1 819 ? 168.286 167.209 166.650 1.00 29.35  ? 819  HIS A CA  1 
ATOM   5396 C  C   . HIS A 1 819 ? 169.645 166.597 166.957 1.00 29.35  ? 819  HIS A C   1 
ATOM   5397 O  O   . HIS A 1 819 ? 170.656 167.034 166.399 1.00 29.35  ? 819  HIS A O   1 
ATOM   5398 C  CB  . HIS A 1 819 ? 168.038 168.432 167.527 1.00 29.35  ? 819  HIS A CB  1 
ATOM   5399 C  CG  . HIS A 1 819 ? 166.719 169.083 167.275 1.00 29.35  ? 819  HIS A CG  1 
ATOM   5400 N  ND1 . HIS A 1 819 ? 165.551 168.639 167.853 1.00 29.35  ? 819  HIS A ND1 1 
ATOM   5401 C  CD2 . HIS A 1 819 ? 166.377 170.131 166.493 1.00 29.35  ? 819  HIS A CD2 1 
ATOM   5402 C  CE1 . HIS A 1 819 ? 164.546 169.392 167.445 1.00 29.35  ? 819  HIS A CE1 1 
ATOM   5403 N  NE2 . HIS A 1 819 ? 165.021 170.305 166.618 1.00 29.35  ? 819  HIS A NE2 1 
ATOM   5404 N  N   . MET A 1 820 ? 169.698 165.602 167.842 1.00 32.90  ? 820  MET A N   1 
ATOM   5405 C  CA  . MET A 1 820 ? 170.978 164.967 168.131 1.00 32.90  ? 820  MET A CA  1 
ATOM   5406 C  C   . MET A 1 820 ? 171.407 164.043 167.002 1.00 32.90  ? 820  MET A C   1 
ATOM   5407 O  O   . MET A 1 820 ? 172.579 164.044 166.611 1.00 32.90  ? 820  MET A O   1 
ATOM   5408 C  CB  . MET A 1 820 ? 170.909 164.201 169.450 1.00 32.90  ? 820  MET A CB  1 
ATOM   5409 C  CG  . MET A 1 820 ? 170.698 165.085 170.658 1.00 32.90  ? 820  MET A CG  1 
ATOM   5410 S  SD  . MET A 1 820 ? 172.087 166.189 170.954 1.00 32.90  ? 820  MET A SD  1 
ATOM   5411 C  CE  . MET A 1 820 ? 171.245 167.767 171.025 1.00 32.90  ? 820  MET A CE  1 
ATOM   5412 N  N   . ILE A 1 821 ? 170.479 163.249 166.457 1.00 30.38  ? 821  ILE A N   1 
ATOM   5413 C  CA  . ILE A 1 821 ? 170.886 162.223 165.497 1.00 30.38  ? 821  ILE A CA  1 
ATOM   5414 C  C   . ILE A 1 821 ? 170.663 162.616 164.045 1.00 30.38  ? 821  ILE A C   1 
ATOM   5415 O  O   . ILE A 1 821 ? 170.910 161.792 163.153 1.00 30.38  ? 821  ILE A O   1 
ATOM   5416 C  CB  . ILE A 1 821 ? 170.173 160.877 165.736 1.00 30.38  ? 821  ILE A CB  1 
ATOM   5417 C  CG1 . ILE A 1 821 ? 168.678 161.000 165.483 1.00 30.38  ? 821  ILE A CG1 1 
ATOM   5418 C  CG2 . ILE A 1 821 ? 170.423 160.388 167.143 1.00 30.38  ? 821  ILE A CG2 1 
ATOM   5419 C  CD1 . ILE A 1 821 ? 167.925 159.738 165.797 1.00 30.38  ? 821  ILE A CD1 1 
ATOM   5420 N  N   . ARG A 1 822 ? 170.206 163.837 163.769 1.00 31.24  ? 822  ARG A N   1 
ATOM   5421 C  CA  . ARG A 1 822 ? 170.047 164.241 162.378 1.00 31.24  ? 822  ARG A CA  1 
ATOM   5422 C  C   . ARG A 1 822 ? 171.394 164.467 161.709 1.00 31.24  ? 822  ARG A C   1 
ATOM   5423 O  O   . ARG A 1 822 ? 171.565 164.156 160.526 1.00 31.24  ? 822  ARG A O   1 
ATOM   5424 C  CB  . ARG A 1 822 ? 169.186 165.498 162.283 1.00 31.24  ? 822  ARG A CB  1 
ATOM   5425 C  CG  . ARG A 1 822 ? 169.720 166.694 163.020 1.00 31.24  ? 822  ARG A CG  1 
ATOM   5426 C  CD  . ARG A 1 822 ? 168.851 167.895 162.761 1.00 31.24  ? 822  ARG A CD  1 
ATOM   5427 N  NE  . ARG A 1 822 ? 168.862 168.263 161.353 1.00 31.24  ? 822  ARG A NE  1 
ATOM   5428 C  CZ  . ARG A 1 822 ? 169.481 169.329 160.870 1.00 31.24  ? 822  ARG A CZ  1 
ATOM   5429 N  NH1 . ARG A 1 822 ? 170.158 170.145 161.656 1.00 31.24  ? 822  ARG A NH1 1 
ATOM   5430 N  NH2 . ARG A 1 822 ? 169.423 169.578 159.566 1.00 31.24  ? 822  ARG A NH2 1 
ATOM   5431 N  N   . THR A 1 823 ? 172.364 164.997 162.445 1.00 35.91  ? 823  THR A N   1 
ATOM   5432 C  CA  . THR A 1 823 ? 173.635 165.421 161.882 1.00 35.91  ? 823  THR A CA  1 
ATOM   5433 C  C   . THR A 1 823 ? 174.784 164.676 162.544 1.00 35.91  ? 823  THR A C   1 
ATOM   5434 O  O   . THR A 1 823 ? 174.794 164.485 163.764 1.00 35.91  ? 823  THR A O   1 
ATOM   5435 C  CB  . THR A 1 823 ? 173.821 166.932 162.043 1.00 35.91  ? 823  THR A CB  1 
ATOM   5436 O  OG1 . THR A 1 823 ? 175.137 167.302 161.622 1.00 35.91  ? 823  THR A OG1 1 
ATOM   5437 C  CG2 . THR A 1 823 ? 173.605 167.353 163.482 1.00 35.91  ? 823  THR A CG2 1 
ATOM   5438 N  N   . ARG A 1 824 ? 175.744 164.238 161.727 1.00 40.94  ? 824  ARG A N   1 
ATOM   5439 C  CA  . ARG A 1 824 ? 176.920 163.564 162.268 1.00 40.94  ? 824  ARG A CA  1 
ATOM   5440 C  C   . ARG A 1 824 ? 177.773 164.521 163.088 1.00 40.94  ? 824  ARG A C   1 
ATOM   5441 O  O   . ARG A 1 824 ? 178.294 164.147 164.145 1.00 40.94  ? 824  ARG A O   1 
ATOM   5442 C  CB  . ARG A 1 824 ? 177.738 162.941 161.139 1.00 40.94  ? 824  ARG A CB  1 
ATOM   5443 C  CG  . ARG A 1 824 ? 177.036 161.789 160.440 1.00 40.94  ? 824  ARG A CG  1 
ATOM   5444 C  CD  . ARG A 1 824 ? 176.692 160.674 161.418 1.00 40.94  ? 824  ARG A CD  1 
ATOM   5445 N  NE  . ARG A 1 824 ? 175.488 159.950 161.023 1.00 40.94  ? 824  ARG A NE  1 
ATOM   5446 C  CZ  . ARG A 1 824 ? 174.393 159.853 161.765 1.00 40.94  ? 824  ARG A CZ  1 
ATOM   5447 N  NH1 . ARG A 1 824 ? 174.314 160.418 162.958 1.00 40.94  ? 824  ARG A NH1 1 
ATOM   5448 N  NH2 . ARG A 1 824 ? 173.351 159.174 161.297 1.00 40.94  ? 824  ARG A NH2 1 
ATOM   5449 N  N   . ARG A 1 825 ? 177.853 165.769 162.642 1.00 47.14  ? 825  ARG A N   1 
ATOM   5450 C  CA  . ARG A 1 825 ? 178.603 166.794 163.353 1.00 47.14  ? 825  ARG A CA  1 
ATOM   5451 C  C   . ARG A 1 825 ? 177.791 167.253 164.554 1.00 47.14  ? 825  ARG A C   1 
ATOM   5452 O  O   . ARG A 1 825 ? 176.578 167.114 164.563 1.00 47.14  ? 825  ARG A O   1 
ATOM   5453 C  CB  . ARG A 1 825 ? 178.892 167.961 162.422 1.00 47.14  ? 825  ARG A CB  1 
ATOM   5454 C  CG  . ARG A 1 825 ? 179.835 167.601 161.288 1.00 47.14  ? 825  ARG A CG  1 
ATOM   5455 C  CD  . ARG A 1 825 ? 179.558 168.427 160.047 1.00 47.14  ? 825  ARG A CD  1 
ATOM   5456 N  NE  . ARG A 1 825 ? 179.480 169.850 160.347 1.00 47.14  ? 825  ARG A NE  1 
ATOM   5457 C  CZ  . ARG A 1 825 ? 179.227 170.787 159.442 1.00 47.14  ? 825  ARG A CZ  1 
ATOM   5458 N  NH1 . ARG A 1 825 ? 179.031 170.447 158.177 1.00 47.14  ? 825  ARG A NH1 1 
ATOM   5459 N  NH2 . ARG A 1 825 ? 179.173 172.060 159.801 1.00 47.14  ? 825  ARG A NH2 1 
ATOM   5460 N  N   . VAL A 1 826 ? 178.454 167.942 165.486 1.00 47.79  ? 826  VAL A N   1 
ATOM   5461 C  CA  . VAL A 1 826 ? 177.860 168.496 166.726 1.00 47.79  ? 826  VAL A CA  1 
ATOM   5462 C  C   . VAL A 1 826 ? 176.428 169.046 166.614 1.00 47.79  ? 826  VAL A C   1 
ATOM   5463 O  O   . VAL A 1 826 ? 176.133 169.864 165.749 1.00 47.79  ? 826  VAL A O   1 
ATOM   5464 C  CB  . VAL A 1 826 ? 178.774 169.571 167.336 1.00 47.79  ? 826  VAL A CB  1 
ATOM   5465 C  CG1 . VAL A 1 826 ? 178.362 169.857 168.767 1.00 47.79  ? 826  VAL A CG1 1 
ATOM   5466 C  CG2 . VAL A 1 826 ? 180.217 169.105 167.299 1.00 47.79  ? 826  VAL A CG2 1 
ATOM   5467 N  N   . PRO A 1 827 ? 175.575 168.689 167.577 1.00 43.52  ? 827  PRO A N   1 
ATOM   5468 C  CA  . PRO A 1 827 ? 174.133 168.953 167.607 1.00 43.52  ? 827  PRO A CA  1 
ATOM   5469 C  C   . PRO A 1 827 ? 173.636 170.382 167.532 1.00 43.52  ? 827  PRO A C   1 
ATOM   5470 O  O   . PRO A 1 827 ? 172.575 170.535 166.955 1.00 43.52  ? 827  PRO A O   1 
ATOM   5471 C  CB  . PRO A 1 827 ? 173.698 168.353 168.944 1.00 43.52  ? 827  PRO A CB  1 
ATOM   5472 C  CG  . PRO A 1 827 ? 174.937 168.292 169.761 1.00 43.52  ? 827  PRO A CG  1 
ATOM   5473 C  CD  . PRO A 1 827 ? 176.018 167.974 168.780 1.00 43.52  ? 827  PRO A CD  1 
ATOM   5474 N  N   . PHE A 1 828 ? 174.237 171.365 168.179 1.00 45.32  ? 828  PHE A N   1 
ATOM   5475 C  CA  . PHE A 1 828 ? 173.712 172.718 168.007 1.00 45.32  ? 828  PHE A CA  1 
ATOM   5476 C  C   . PHE A 1 828 ? 174.718 173.792 167.627 1.00 45.32  ? 828  PHE A C   1 
ATOM   5477 O  O   . PHE A 1 828 ? 174.366 174.775 166.985 1.00 45.32  ? 828  PHE A O   1 
ATOM   5478 C  CB  . PHE A 1 828 ? 172.877 173.159 169.205 1.00 45.32  ? 828  PHE A CB  1 
ATOM   5479 C  CG  . PHE A 1 828 ? 171.406 173.235 168.915 1.00 45.32  ? 828  PHE A CG  1 
ATOM   5480 C  CD1 . PHE A 1 828 ? 170.883 174.312 168.226 1.00 45.32  ? 828  PHE A CD1 1 
ATOM   5481 C  CD2 . PHE A 1 828 ? 170.550 172.236 169.329 1.00 45.32  ? 828  PHE A CD2 1 
ATOM   5482 C  CE1 . PHE A 1 828 ? 169.533 174.391 167.954 1.00 45.32  ? 828  PHE A CE1 1 
ATOM   5483 C  CE2 . PHE A 1 828 ? 169.199 172.309 169.058 1.00 45.32  ? 828  PHE A CE2 1 
ATOM   5484 C  CZ  . PHE A 1 828 ? 168.689 173.387 168.371 1.00 45.32  ? 828  PHE A CZ  1 
ATOM   5485 N  N   . ILE A 1 829 ? 175.966 173.604 168.035 1.00 47.78  ? 829  ILE A N   1 
ATOM   5486 C  CA  . ILE A 1 829 ? 177.012 174.584 167.772 1.00 47.78  ? 829  ILE A CA  1 
ATOM   5487 C  C   . ILE A 1 829 ? 177.791 174.394 166.480 1.00 47.78  ? 829  ILE A C   1 
ATOM   5488 O  O   . ILE A 1 829 ? 178.592 175.245 166.116 1.00 47.78  ? 829  ILE A O   1 
ATOM   5489 C  CB  . ILE A 1 829 ? 178.021 174.620 168.927 1.00 47.78  ? 829  ILE A CB  1 
ATOM   5490 C  CG1 . ILE A 1 829 ? 178.583 173.224 169.170 1.00 47.78  ? 829  ILE A CG1 1 
ATOM   5491 C  CG2 . ILE A 1 829 ? 177.362 175.144 170.191 1.00 47.78  ? 829  ILE A CG2 1 
ATOM   5492 C  CD1 . ILE A 1 829 ? 179.360 173.097 170.461 1.00 47.78  ? 829  ILE A CD1 1 
ATOM   5493 N  N   . GLN A 1 830 ? 177.558 173.292 165.781 1.00 50.32  ? 830  GLN A N   1 
ATOM   5494 C  CA  . GLN A 1 830 ? 178.287 173.032 164.547 1.00 50.32  ? 830  GLN A CA  1 
ATOM   5495 C  C   . GLN A 1 830 ? 177.362 172.740 163.374 1.00 50.32  ? 830  GLN A C   1 
ATOM   5496 O  O   . GLN A 1 830 ? 177.778 172.795 162.221 1.00 50.32  ? 830  GLN A O   1 
ATOM   5497 C  CB  . GLN A 1 830 ? 179.266 171.884 164.757 1.00 50.32  ? 830  GLN A CB  1 
ATOM   5498 C  CG  . GLN A 1 830 ? 180.269 171.704 163.638 1.00 50.32  ? 830  GLN A CG  1 
ATOM   5499 C  CD  . GLN A 1 830 ? 181.400 170.784 164.038 1.00 50.32  ? 830  GLN A CD  1 
ATOM   5500 O  OE1 . GLN A 1 830 ? 181.887 170.840 165.164 1.00 50.32  ? 830  GLN A OE1 1 
ATOM   5501 N  NE2 . GLN A 1 830 ? 181.825 169.929 163.117 1.00 50.32  ? 830  GLN A NE2 1 
ATOM   5502 N  N   . SER A 1 831 ? 176.109 172.424 163.682 1.00 47.93  ? 831  SER A N   1 
ATOM   5503 C  CA  . SER A 1 831 ? 175.091 172.144 162.674 1.00 47.93  ? 831  SER A CA  1 
ATOM   5504 C  C   . SER A 1 831 ? 173.725 172.243 163.332 1.00 47.93  ? 831  SER A C   1 
ATOM   5505 O  O   . SER A 1 831 ? 173.384 171.411 164.175 1.00 47.93  ? 831  SER A O   1 
ATOM   5506 C  CB  . SER A 1 831 ? 175.292 170.761 162.058 1.00 47.93  ? 831  SER A CB  1 
ATOM   5507 O  OG  . SER A 1 831 ? 174.248 170.452 161.155 1.00 47.93  ? 831  SER A OG  1 
ATOM   5508 N  N   . CYS A 1 832 ? 172.949 173.247 162.946 1.00 46.09  ? 832  CYS A N   1 
ATOM   5509 C  CA  . CYS A 1 832 ? 171.646 173.505 163.539 1.00 46.09  ? 832  CYS A CA  1 
ATOM   5510 C  C   . CYS A 1 832 ? 170.546 172.957 162.642 1.00 46.09  ? 832  CYS A C   1 
ATOM   5511 O  O   . CYS A 1 832 ? 170.802 172.363 161.594 1.00 46.09  ? 832  CYS A O   1 
ATOM   5512 C  CB  . CYS A 1 832 ? 171.445 175.005 163.778 1.00 46.09  ? 832  CYS A CB  1 
ATOM   5513 S  SG  . CYS A 1 832 ? 169.842 175.439 164.485 1.00 46.09  ? 832  CYS A SG  1 
ATOM   5514 N  N   . ALA A 1 833 ? 169.306 173.162 163.073 1.00 40.27  ? 833  ALA A N   1 
ATOM   5515 C  CA  . ALA A 1 833 ? 168.133 172.717 162.339 1.00 40.27  ? 833  ALA A CA  1 
ATOM   5516 C  C   . ALA A 1 833 ? 167.308 173.914 161.885 1.00 40.27  ? 833  ALA A C   1 
ATOM   5517 O  O   . ALA A 1 833 ? 167.408 175.012 162.436 1.00 40.27  ? 833  ALA A O   1 
ATOM   5518 C  CB  . ALA A 1 833 ? 167.273 171.781 163.192 1.00 40.27  ? 833  ALA A CB  1 
ATOM   5519 N  N   . SER A 1 834 ? 166.487 173.686 160.865 1.00 38.82  ? 834  SER A N   1 
ATOM   5520 C  CA  . SER A 1 834 ? 165.679 174.756 160.305 1.00 38.82  ? 834  SER A CA  1 
ATOM   5521 C  C   . SER A 1 834 ? 164.544 175.131 161.253 1.00 38.82  ? 834  SER A C   1 
ATOM   5522 O  O   . SER A 1 834 ? 164.149 174.361 162.131 1.00 38.82  ? 834  SER A O   1 
ATOM   5523 C  CB  . SER A 1 834 ? 165.112 174.348 158.949 1.00 38.82  ? 834  SER A CB  1 
ATOM   5524 O  OG  . SER A 1 834 ? 163.882 173.664 159.099 1.00 38.82  ? 834  SER A OG  1 
ATOM   5525 N  N   . TRP A 1 835 ? 164.015 176.337 161.054 1.00 37.15  ? 835  TRP A N   1 
ATOM   5526 C  CA  . TRP A 1 835 ? 162.997 176.870 161.958 1.00 37.15  ? 835  TRP A CA  1 
ATOM   5527 C  C   . TRP A 1 835 ? 161.742 176.011 162.046 1.00 37.15  ? 835  TRP A C   1 
ATOM   5528 O  O   . TRP A 1 835 ? 161.250 175.803 163.169 1.00 37.15  ? 835  TRP A O   1 
ATOM   5529 C  CB  . TRP A 1 835 ? 162.649 178.304 161.548 1.00 37.15  ? 835  TRP A CB  1 
ATOM   5530 C  CG  . TRP A 1 835 ? 163.697 179.301 161.910 1.00 37.15  ? 835  TRP A CG  1 
ATOM   5531 C  CD1 . TRP A 1 835 ? 164.336 180.156 161.064 1.00 37.15  ? 835  TRP A CD1 1 
ATOM   5532 C  CD2 . TRP A 1 835 ? 164.230 179.554 163.216 1.00 37.15  ? 835  TRP A CD2 1 
ATOM   5533 N  NE1 . TRP A 1 835 ? 165.235 180.926 161.760 1.00 37.15  ? 835  TRP A NE1 1 
ATOM   5534 C  CE2 . TRP A 1 835 ? 165.188 180.575 163.083 1.00 37.15  ? 835  TRP A CE2 1 
ATOM   5535 C  CE3 . TRP A 1 835 ? 163.990 179.018 164.483 1.00 37.15  ? 835  TRP A CE3 1 
ATOM   5536 C  CZ2 . TRP A 1 835 ? 165.906 181.069 164.167 1.00 37.15  ? 835  TRP A CZ2 1 
ATOM   5537 C  CZ3 . TRP A 1 835 ? 164.704 179.508 165.557 1.00 37.15  ? 835  TRP A CZ3 1 
ATOM   5538 C  CH2 . TRP A 1 835 ? 165.650 180.523 165.393 1.00 37.15  ? 835  TRP A CH2 1 
ATOM   5539 N  N   . PRO A 1 836 ? 161.154 175.520 160.946 1.00 34.44  ? 836  PRO A N   1 
ATOM   5540 C  CA  . PRO A 1 836 ? 159.938 174.703 161.097 1.00 34.44  ? 836  PRO A CA  1 
ATOM   5541 C  C   . PRO A 1 836 ? 160.138 173.484 161.974 1.00 34.44  ? 836  PRO A C   1 
ATOM   5542 O  O   . PRO A 1 836 ? 159.251 173.147 162.767 1.00 34.44  ? 836  PRO A O   1 
ATOM   5543 C  CB  . PRO A 1 836 ? 159.599 174.312 159.654 1.00 34.44  ? 836  PRO A CB  1 
ATOM   5544 C  CG  . PRO A 1 836 ? 160.218 175.361 158.828 1.00 34.44  ? 836  PRO A CG  1 
ATOM   5545 C  CD  . PRO A 1 836 ? 161.480 175.737 159.526 1.00 34.44  ? 836  PRO A CD  1 
ATOM   5546 N  N   . LEU A 1 837 ? 161.284 172.831 161.829 1.00 34.88  ? 837  LEU A N   1 
ATOM   5547 C  CA  . LEU A 1 837 ? 161.601 171.636 162.598 1.00 34.88  ? 837  LEU A CA  1 
ATOM   5548 C  C   . LEU A 1 837 ? 161.776 171.950 164.063 1.00 34.88  ? 837  LEU A C   1 
ATOM   5549 O  O   . LEU A 1 837 ? 161.263 171.242 164.910 1.00 34.88  ? 837  LEU A O   1 
ATOM   5550 C  CB  . LEU A 1 837 ? 162.870 170.987 162.081 1.00 34.88  ? 837  LEU A CB  1 
ATOM   5551 C  CG  . LEU A 1 837 ? 163.117 169.639 162.729 1.00 34.88  ? 837  LEU A CG  1 
ATOM   5552 C  CD1 . LEU A 1 837 ? 161.873 168.795 162.546 1.00 34.88  ? 837  LEU A CD1 1 
ATOM   5553 C  CD2 . LEU A 1 837 ? 164.318 168.973 162.090 1.00 34.88  ? 837  LEU A CD2 1 
ATOM   5554 N  N   . MET A 1 838 ? 162.516 173.007 164.366 1.00 37.42  ? 838  MET A N   1 
ATOM   5555 C  CA  . MET A 1 838 ? 162.725 173.418 165.747 1.00 37.42  ? 838  MET A CA  1 
ATOM   5556 C  C   . MET A 1 838 ? 161.417 173.837 166.393 1.00 37.42  ? 838  MET A C   1 
ATOM   5557 O  O   . MET A 1 838 ? 161.200 173.597 167.569 1.00 37.42  ? 838  MET A O   1 
ATOM   5558 C  CB  . MET A 1 838 ? 163.740 174.543 165.844 1.00 37.42  ? 838  MET A CB  1 
ATOM   5559 C  CG  . MET A 1 838 ? 165.092 174.187 165.270 1.00 37.42  ? 838  MET A CG  1 
ATOM   5560 S  SD  . MET A 1 838 ? 166.401 175.162 166.015 1.00 37.42  ? 838  MET A SD  1 
ATOM   5561 C  CE  . MET A 1 838 ? 166.443 174.455 167.658 1.00 37.42  ? 838  MET A CE  1 
ATOM   5562 N  N   . ILE A 1 839 ? 160.565 174.511 165.636 1.00 34.55  ? 839  ILE A N   1 
ATOM   5563 C  CA  . ILE A 1 839 ? 159.281 174.933 166.154 1.00 34.55  ? 839  ILE A CA  1 
ATOM   5564 C  C   . ILE A 1 839 ? 158.342 173.753 166.419 1.00 34.55  ? 839  ILE A C   1 
ATOM   5565 O  O   . ILE A 1 839 ? 157.921 173.580 167.558 1.00 34.55  ? 839  ILE A O   1 
ATOM   5566 C  CB  . ILE A 1 839 ? 158.623 175.981 165.250 1.00 34.55  ? 839  ILE A CB  1 
ATOM   5567 C  CG1 . ILE A 1 839 ? 159.339 177.319 165.422 1.00 34.55  ? 839  ILE A CG1 1 
ATOM   5568 C  CG2 . ILE A 1 839 ? 157.149 176.122 165.579 1.00 34.55  ? 839  ILE A CG2 1 
ATOM   5569 C  CD1 . ILE A 1 839 ? 158.607 178.490 164.809 1.00 34.55  ? 839  ILE A CD1 1 
ATOM   5570 N  N   . MET A 1 840 ? 158.020 172.954 165.395 1.00 31.02  ? 840  MET A N   1 
ATOM   5571 C  CA  . MET A 1 840 ? 157.137 171.803 165.552 1.00 31.02  ? 840  MET A CA  1 
ATOM   5572 C  C   . MET A 1 840 ? 157.589 170.909 166.699 1.00 31.02  ? 840  MET A C   1 
ATOM   5573 O  O   . MET A 1 840 ? 156.755 170.318 167.392 1.00 31.02  ? 840  MET A O   1 
ATOM   5574 C  CB  . MET A 1 840 ? 157.059 171.015 164.248 1.00 31.02  ? 840  MET A CB  1 
ATOM   5575 C  CG  . MET A 1 840 ? 156.371 171.765 163.126 1.00 31.02  ? 840  MET A CG  1 
ATOM   5576 S  SD  . MET A 1 840 ? 154.676 172.218 163.523 1.00 31.02  ? 840  MET A SD  1 
ATOM   5577 C  CE  . MET A 1 840 ? 154.040 170.659 164.129 1.00 31.02  ? 840  MET A CE  1 
ATOM   5578 N  N   . THR A 1 841 ? 158.899 170.803 166.925 1.00 27.93  ? 841  THR A N   1 
ATOM   5579 C  CA  . THR A 1 841 ? 159.380 170.062 168.085 1.00 27.93  ? 841  THR A CA  1 
ATOM   5580 C  C   . THR A 1 841 ? 158.890 170.696 169.378 1.00 27.93  ? 841  THR A C   1 
ATOM   5581 O  O   . THR A 1 841 ? 158.440 169.994 170.289 1.00 27.93  ? 841  THR A O   1 
ATOM   5582 C  CB  . THR A 1 841 ? 160.905 169.991 168.068 1.00 27.93  ? 841  THR A CB  1 
ATOM   5583 O  OG1 . THR A 1 841 ? 161.335 169.198 166.956 1.00 27.93  ? 841  THR A OG1 1 
ATOM   5584 C  CG2 . THR A 1 841 ? 161.428 169.379 169.348 1.00 27.93  ? 841  THR A CG2 1 
ATOM   5585 N  N   . VAL A 1 842 ? 158.951 172.025 169.470 1.00 27.64  ? 842  VAL A N   1 
ATOM   5586 C  CA  . VAL A 1 842 ? 158.475 172.701 170.673 1.00 27.64  ? 842  VAL A CA  1 
ATOM   5587 C  C   . VAL A 1 842 ? 156.977 172.496 170.847 1.00 27.64  ? 842  VAL A C   1 
ATOM   5588 O  O   . VAL A 1 842 ? 156.495 172.232 171.956 1.00 27.64  ? 842  VAL A O   1 
ATOM   5589 C  CB  . VAL A 1 842 ? 158.841 174.194 170.631 1.00 27.64  ? 842  VAL A CB  1 
ATOM   5590 C  CG1 . VAL A 1 842 ? 158.061 174.955 171.682 1.00 27.64  ? 842  VAL A CG1 1 
ATOM   5591 C  CG2 . VAL A 1 842 ? 160.332 174.373 170.849 1.00 27.64  ? 842  VAL A CG2 1 
ATOM   5592 N  N   . ILE A 1 843 ? 156.217 172.608 169.758 1.00 26.20  ? 843  ILE A N   1 
ATOM   5593 C  CA  . ILE A 1 843 ? 154.769 172.456 169.850 1.00 26.20  ? 843  ILE A CA  1 
ATOM   5594 C  C   . ILE A 1 843 ? 154.403 171.043 170.291 1.00 26.20  ? 843  ILE A C   1 
ATOM   5595 O  O   . ILE A 1 843 ? 153.519 170.850 171.133 1.00 26.20  ? 843  ILE A O   1 
ATOM   5596 C  CB  . ILE A 1 843 ? 154.103 172.826 168.514 1.00 26.20  ? 843  ILE A CB  1 
ATOM   5597 C  CG1 . ILE A 1 843 ? 153.997 174.346 168.390 1.00 26.20  ? 843  ILE A CG1 1 
ATOM   5598 C  CG2 . ILE A 1 843 ? 152.734 172.185 168.398 1.00 26.20  ? 843  ILE A CG2 1 
ATOM   5599 C  CD1 . ILE A 1 843 ? 153.468 174.814 167.061 1.00 26.20  ? 843  ILE A CD1 1 
ATOM   5600 N  N   . VAL A 1 844 ? 155.079 170.035 169.739 1.00 23.72  ? 844  VAL A N   1 
ATOM   5601 C  CA  . VAL A 1 844 ? 154.776 168.657 170.115 1.00 23.72  ? 844  VAL A CA  1 
ATOM   5602 C  C   . VAL A 1 844 ? 155.212 168.375 171.548 1.00 23.72  ? 844  VAL A C   1 
ATOM   5603 O  O   . VAL A 1 844 ? 154.541 167.636 172.273 1.00 23.72  ? 844  VAL A O   1 
ATOM   5604 C  CB  . VAL A 1 844 ? 155.407 167.679 169.114 1.00 23.72  ? 844  VAL A CB  1 
ATOM   5605 C  CG1 . VAL A 1 844 ? 155.372 166.271 169.655 1.00 23.72  ? 844  VAL A CG1 1 
ATOM   5606 C  CG2 . VAL A 1 844 ? 154.649 167.746 167.812 1.00 23.72  ? 844  VAL A CG2 1 
ATOM   5607 N  N   . MET A 1 845 ? 156.333 168.953 171.988 1.00 24.85  ? 845  MET A N   1 
ATOM   5608 C  CA  . MET A 1 845 ? 156.714 168.816 173.390 1.00 24.85  ? 845  MET A CA  1 
ATOM   5609 C  C   . MET A 1 845 ? 155.643 169.389 174.303 1.00 24.85  ? 845  MET A C   1 
ATOM   5610 O  O   . MET A 1 845 ? 155.282 168.776 175.316 1.00 24.85  ? 845  MET A O   1 
ATOM   5611 C  CB  . MET A 1 845 ? 158.037 169.524 173.661 1.00 24.85  ? 845  MET A CB  1 
ATOM   5612 C  CG  . MET A 1 845 ? 159.254 168.642 173.685 1.00 24.85  ? 845  MET A CG  1 
ATOM   5613 S  SD  . MET A 1 845 ? 160.724 169.670 173.590 1.00 24.85  ? 845  MET A SD  1 
ATOM   5614 C  CE  . MET A 1 845 ? 160.354 170.909 174.828 1.00 24.85  ? 845  MET A CE  1 
ATOM   5615 N  N   . ILE A 1 846 ? 155.140 170.578 173.971 1.00 24.20  ? 846  ILE A N   1 
ATOM   5616 C  CA  . ILE A 1 846 ? 154.111 171.207 174.791 1.00 24.20  ? 846  ILE A CA  1 
ATOM   5617 C  C   . ILE A 1 846 ? 152.847 170.361 174.798 1.00 24.20  ? 846  ILE A C   1 
ATOM   5618 O  O   . ILE A 1 846 ? 152.218 170.166 175.845 1.00 24.20  ? 846  ILE A O   1 
ATOM   5619 C  CB  . ILE A 1 846 ? 153.841 172.639 174.296 1.00 24.20  ? 846  ILE A CB  1 
ATOM   5620 C  CG1 . ILE A 1 846 ? 155.015 173.546 174.660 1.00 24.20  ? 846  ILE A CG1 1 
ATOM   5621 C  CG2 . ILE A 1 846 ? 152.545 173.172 174.871 1.00 24.20  ? 846  ILE A CG2 1 
ATOM   5622 C  CD1 . ILE A 1 846 ? 155.408 173.473 176.117 1.00 24.20  ? 846  ILE A CD1 1 
ATOM   5623 N  N   . VAL A 1 847 ? 152.461 169.835 173.635 1.00 23.10  ? 847  VAL A N   1 
ATOM   5624 C  CA  . VAL A 1 847 ? 151.280 168.981 173.561 1.00 23.10  ? 847  VAL A CA  1 
ATOM   5625 C  C   . VAL A 1 847 ? 151.465 167.737 174.418 1.00 23.10  ? 847  VAL A C   1 
ATOM   5626 O  O   . VAL A 1 847 ? 150.560 167.335 175.157 1.00 23.10  ? 847  VAL A O   1 
ATOM   5627 C  CB  . VAL A 1 847 ? 150.972 168.620 172.097 1.00 23.10  ? 847  VAL A CB  1 
ATOM   5628 C  CG1 . VAL A 1 847 ? 149.971 167.485 172.032 1.00 23.10  ? 847  VAL A CG1 1 
ATOM   5629 C  CG2 . VAL A 1 847 ? 150.440 169.833 171.360 1.00 23.10  ? 847  VAL A CG2 1 
ATOM   5630 N  N   . GLY A 1 848 ? 152.641 167.114 174.344 1.00 23.15  ? 848  GLY A N   1 
ATOM   5631 C  CA  . GLY A 1 848 ? 152.871 165.898 175.105 1.00 23.15  ? 848  GLY A CA  1 
ATOM   5632 C  C   . GLY A 1 848 ? 152.874 166.127 176.602 1.00 23.15  ? 848  GLY A C   1 
ATOM   5633 O  O   . GLY A 1 848 ? 152.271 165.359 177.355 1.00 23.15  ? 848  GLY A O   1 
ATOM   5634 N  N   . ILE A 1 849 ? 153.551 167.182 177.057 1.00 23.79  ? 849  ILE A N   1 
ATOM   5635 C  CA  . ILE A 1 849 ? 153.578 167.476 178.486 1.00 23.79  ? 849  ILE A CA  1 
ATOM   5636 C  C   . ILE A 1 849 ? 152.189 167.851 178.985 1.00 23.79  ? 849  ILE A C   1 
ATOM   5637 O  O   . ILE A 1 849 ? 151.756 167.399 180.050 1.00 23.79  ? 849  ILE A O   1 
ATOM   5638 C  CB  . ILE A 1 849 ? 154.604 168.581 178.791 1.00 23.79  ? 849  ILE A CB  1 
ATOM   5639 C  CG1 . ILE A 1 849 ? 156.024 168.024 178.727 1.00 23.79  ? 849  ILE A CG1 1 
ATOM   5640 C  CG2 . ILE A 1 849 ? 154.343 169.190 180.152 1.00 23.79  ? 849  ILE A CG2 1 
ATOM   5641 C  CD1 . ILE A 1 849 ? 157.094 169.073 178.902 1.00 23.79  ? 849  ILE A CD1 1 
ATOM   5642 N  N   . ALA A 1 850 ? 151.465 168.671 178.225 1.00 24.81  ? 850  ALA A N   1 
ATOM   5643 C  CA  . ALA A 1 850 ? 150.169 169.173 178.655 1.00 24.81  ? 850  ALA A CA  1 
ATOM   5644 C  C   . ALA A 1 850 ? 149.015 168.234 178.335 1.00 24.81  ? 850  ALA A C   1 
ATOM   5645 O  O   . ALA A 1 850 ? 147.886 168.515 178.746 1.00 24.81  ? 850  ALA A O   1 
ATOM   5646 C  CB  . ALA A 1 850 ? 149.897 170.537 178.019 1.00 24.81  ? 850  ALA A CB  1 
ATOM   5647 N  N   . LEU A 1 851 ? 149.257 167.144 177.609 1.00 26.05  ? 851  LEU A N   1 
ATOM   5648 C  CA  . LEU A 1 851 ? 148.171 166.213 177.306 1.00 26.05  ? 851  LEU A CA  1 
ATOM   5649 C  C   . LEU A 1 851 ? 147.568 165.574 178.550 1.00 26.05  ? 851  LEU A C   1 
ATOM   5650 O  O   . LEU A 1 851 ? 146.330 165.523 178.646 1.00 26.05  ? 851  LEU A O   1 
ATOM   5651 C  CB  . LEU A 1 851 ? 148.649 165.151 176.313 1.00 26.05  ? 851  LEU A CB  1 
ATOM   5652 C  CG  . LEU A 1 851 ? 147.520 164.400 175.612 1.00 26.05  ? 851  LEU A CG  1 
ATOM   5653 C  CD1 . LEU A 1 851 ? 146.618 165.381 174.902 1.00 26.05  ? 851  LEU A CD1 1 
ATOM   5654 C  CD2 . LEU A 1 851 ? 148.081 163.394 174.632 1.00 26.05  ? 851  LEU A CD2 1 
ATOM   5655 N  N   . PRO A 1 852 ? 148.340 165.058 179.514 1.00 28.64  ? 852  PRO A N   1 
ATOM   5656 C  CA  . PRO A 1 852 ? 147.709 164.536 180.735 1.00 28.64  ? 852  PRO A CA  1 
ATOM   5657 C  C   . PRO A 1 852 ? 146.902 165.572 181.494 1.00 28.64  ? 852  PRO A C   1 
ATOM   5658 O  O   . PRO A 1 852 ? 145.875 165.221 182.084 1.00 28.64  ? 852  PRO A O   1 
ATOM   5659 C  CB  . PRO A 1 852 ? 148.900 164.039 181.561 1.00 28.64  ? 852  PRO A CB  1 
ATOM   5660 C  CG  . PRO A 1 852 ? 149.942 163.742 180.559 1.00 28.64  ? 852  PRO A CG  1 
ATOM   5661 C  CD  . PRO A 1 852 ? 149.792 164.806 179.521 1.00 28.64  ? 852  PRO A CD  1 
ATOM   5662 N  N   . PHE A 1 853 ? 147.319 166.837 181.494 1.00 31.31  ? 853  PHE A N   1 
ATOM   5663 C  CA  . PHE A 1 853 ? 146.596 167.894 182.198 1.00 31.31  ? 853  PHE A CA  1 
ATOM   5664 C  C   . PHE A 1 853 ? 145.582 168.497 181.232 1.00 31.31  ? 853  PHE A C   1 
ATOM   5665 O  O   . PHE A 1 853 ? 145.689 169.646 180.806 1.00 31.31  ? 853  PHE A O   1 
ATOM   5666 C  CB  . PHE A 1 853 ? 147.559 168.949 182.727 1.00 31.31  ? 853  PHE A CB  1 
ATOM   5667 C  CG  . PHE A 1 853 ? 148.718 168.385 183.486 1.00 31.31  ? 853  PHE A CG  1 
ATOM   5668 C  CD1 . PHE A 1 853 ? 149.968 168.966 183.387 1.00 31.31  ? 853  PHE A CD1 1 
ATOM   5669 C  CD2 . PHE A 1 853 ? 148.559 167.284 184.304 1.00 31.31  ? 853  PHE A CD2 1 
ATOM   5670 C  CE1 . PHE A 1 853 ? 151.038 168.455 184.080 1.00 31.31  ? 853  PHE A CE1 1 
ATOM   5671 C  CE2 . PHE A 1 853 ? 149.626 166.770 185.000 1.00 31.31  ? 853  PHE A CE2 1 
ATOM   5672 C  CZ  . PHE A 1 853 ? 150.868 167.356 184.888 1.00 31.31  ? 853  PHE A CZ  1 
ATOM   5673 N  N   . SER A 1 854 ? 144.579 167.701 180.890 1.00 37.46  ? 854  SER A N   1 
ATOM   5674 C  CA  . SER A 1 854 ? 143.569 168.106 179.924 1.00 37.46  ? 854  SER A CA  1 
ATOM   5675 C  C   . SER A 1 854 ? 142.363 167.192 180.082 1.00 37.46  ? 854  SER A C   1 
ATOM   5676 O  O   . SER A 1 854 ? 142.486 166.097 180.636 1.00 37.46  ? 854  SER A O   1 
ATOM   5677 C  CB  . SER A 1 854 ? 144.106 168.030 178.486 1.00 37.46  ? 854  SER A CB  1 
ATOM   5678 O  OG  . SER A 1 854 ? 143.933 166.727 177.957 1.00 37.46  ? 854  SER A OG  1 
ATOM   5679 N  N   . PRO A 1 855 ? 141.192 167.621 179.607 1.00 43.89  ? 855  PRO A N   1 
ATOM   5680 C  CA  . PRO A 1 855 ? 140.049 166.699 179.550 1.00 43.89  ? 855  PRO A CA  1 
ATOM   5681 C  C   . PRO A 1 855 ? 140.310 165.483 178.685 1.00 43.89  ? 855  PRO A C   1 
ATOM   5682 O  O   . PRO A 1 855 ? 139.699 164.433 178.918 1.00 43.89  ? 855  PRO A O   1 
ATOM   5683 C  CB  . PRO A 1 855 ? 138.921 167.567 178.973 1.00 43.89  ? 855  PRO A CB  1 
ATOM   5684 C  CG  . PRO A 1 855 ? 139.611 168.729 178.333 1.00 43.89  ? 855  PRO A CG  1 
ATOM   5685 C  CD  . PRO A 1 855 ? 140.826 168.976 179.164 1.00 43.89  ? 855  PRO A CD  1 
ATOM   5686 N  N   . LEU A 1 856 ? 141.207 165.587 177.701 1.00 44.51  ? 856  LEU A N   1 
ATOM   5687 C  CA  . LEU A 1 856 ? 141.515 164.462 176.826 1.00 44.51  ? 856  LEU A CA  1 
ATOM   5688 C  C   . LEU A 1 856 ? 142.176 163.308 177.566 1.00 44.51  ? 856  LEU A C   1 
ATOM   5689 O  O   . LEU A 1 856 ? 142.237 162.198 177.027 1.00 44.51  ? 856  LEU A O   1 
ATOM   5690 C  CB  . LEU A 1 856 ? 142.418 164.920 175.683 1.00 44.51  ? 856  LEU A CB  1 
ATOM   5691 C  CG  . LEU A 1 856 ? 141.710 165.409 174.421 1.00 44.51  ? 856  LEU A CG  1 
ATOM   5692 C  CD1 . LEU A 1 856 ? 142.665 166.218 173.559 1.00 44.51  ? 856  LEU A CD1 1 
ATOM   5693 C  CD2 . LEU A 1 856 ? 141.142 164.232 173.647 1.00 44.51  ? 856  LEU A CD2 1 
ATOM   5694 N  N   . ALA A 1 857 ? 142.673 163.543 178.781 1.00 42.10  ? 857  ALA A N   1 
ATOM   5695 C  CA  . ALA A 1 857 ? 143.320 162.475 179.533 1.00 42.10  ? 857  ALA A CA  1 
ATOM   5696 C  C   . ALA A 1 857 ? 142.347 161.345 179.839 1.00 42.10  ? 857  ALA A C   1 
ATOM   5697 O  O   . ALA A 1 857 ? 142.721 160.167 179.798 1.00 42.10  ? 857  ALA A O   1 
ATOM   5698 C  CB  . ALA A 1 857 ? 143.915 163.032 180.823 1.00 42.10  ? 857  ALA A CB  1 
ATOM   5699 N  N   . SER A 1 858 ? 141.095 161.684 180.151 1.00 47.54  ? 858  SER A N   1 
ATOM   5700 C  CA  . SER A 1 858 ? 140.123 160.663 180.532 1.00 47.54  ? 858  SER A CA  1 
ATOM   5701 C  C   . SER A 1 858 ? 139.879 159.674 179.401 1.00 47.54  ? 858  SER A C   1 
ATOM   5702 O  O   . SER A 1 858 ? 139.840 158.460 179.627 1.00 47.54  ? 858  SER A O   1 
ATOM   5703 C  CB  . SER A 1 858 ? 138.812 161.324 180.957 1.00 47.54  ? 858  SER A CB  1 
ATOM   5704 O  OG  . SER A 1 858 ? 138.235 162.046 179.883 1.00 47.54  ? 858  SER A OG  1 
ATOM   5705 N  N   . TYR A 1 859 ? 139.713 160.172 178.175 1.00 48.88  ? 859  TYR A N   1 
ATOM   5706 C  CA  . TYR A 1 859 ? 139.463 159.289 177.044 1.00 48.88  ? 859  TYR A CA  1 
ATOM   5707 C  C   . TYR A 1 859 ? 140.721 158.588 176.551 1.00 48.88  ? 859  TYR A C   1 
ATOM   5708 O  O   . TYR A 1 859 ? 140.614 157.554 175.884 1.00 48.88  ? 859  TYR A O   1 
ATOM   5709 C  CB  . TYR A 1 859 ? 138.824 160.065 175.891 1.00 48.88  ? 859  TYR A CB  1 
ATOM   5710 C  CG  . TYR A 1 859 ? 138.008 161.259 176.328 1.00 48.88  ? 859  TYR A CG  1 
ATOM   5711 C  CD1 . TYR A 1 859 ? 136.695 161.108 176.750 1.00 48.88  ? 859  TYR A CD1 1 
ATOM   5712 C  CD2 . TYR A 1 859 ? 138.545 162.537 176.302 1.00 48.88  ? 859  TYR A CD2 1 
ATOM   5713 C  CE1 . TYR A 1 859 ? 135.944 162.196 177.148 1.00 48.88  ? 859  TYR A CE1 1 
ATOM   5714 C  CE2 . TYR A 1 859 ? 137.800 163.631 176.694 1.00 48.88  ? 859  TYR A CE2 1 
ATOM   5715 C  CZ  . TYR A 1 859 ? 136.502 163.456 177.118 1.00 48.88  ? 859  TYR A CZ  1 
ATOM   5716 O  OH  . TYR A 1 859 ? 135.760 164.546 177.510 1.00 48.88  ? 859  TYR A OH  1 
ATOM   5717 N  N   . LEU A 1 860 ? 141.900 159.118 176.862 1.00 41.58  ? 860  LEU A N   1 
ATOM   5718 C  CA  . LEU A 1 860 ? 143.157 158.516 176.443 1.00 41.58  ? 860  LEU A CA  1 
ATOM   5719 C  C   . LEU A 1 860 ? 143.726 157.561 177.482 1.00 41.58  ? 860  LEU A C   1 
ATOM   5720 O  O   . LEU A 1 860 ? 144.829 157.043 177.288 1.00 41.58  ? 860  LEU A O   1 
ATOM   5721 C  CB  . LEU A 1 860 ? 144.185 159.604 176.127 1.00 41.58  ? 860  LEU A CB  1 
ATOM   5722 C  CG  . LEU A 1 860 ? 143.982 160.385 174.829 1.00 41.58  ? 860  LEU A CG  1 
ATOM   5723 C  CD1 . LEU A 1 860 ? 144.912 161.578 174.772 1.00 41.58  ? 860  LEU A CD1 1 
ATOM   5724 C  CD2 . LEU A 1 860 ? 144.199 159.490 173.633 1.00 41.58  ? 860  LEU A CD2 1 
ATOM   5725 N  N   . GLN A 1 861 ? 142.999 157.320 178.573 1.00 39.25  ? 861  GLN A N   1 
ATOM   5726 C  CA  . GLN A 1 861 ? 143.475 156.489 179.681 1.00 39.25  ? 861  GLN A CA  1 
ATOM   5727 C  C   . GLN A 1 861 ? 144.817 156.989 180.209 1.00 39.25  ? 861  GLN A C   1 
ATOM   5728 O  O   . GLN A 1 861 ? 145.716 156.209 180.526 1.00 39.25  ? 861  GLN A O   1 
ATOM   5729 C  CB  . GLN A 1 861 ? 143.548 155.015 179.281 1.00 39.25  ? 861  GLN A CB  1 
ATOM   5730 C  CG  . GLN A 1 861 ? 142.361 154.561 178.453 1.00 39.25  ? 861  GLN A CG  1 
ATOM   5731 C  CD  . GLN A 1 861 ? 142.020 153.105 178.672 1.00 39.25  ? 861  GLN A CD  1 
ATOM   5732 O  OE1 . GLN A 1 861 ? 142.257 152.555 179.747 1.00 39.25  ? 861  GLN A OE1 1 
ATOM   5733 N  NE2 . GLN A 1 861 ? 141.454 152.470 177.653 1.00 39.25  ? 861  GLN A NE2 1 
ATOM   5734 N  N   . LEU A 1 862 ? 144.946 158.308 180.298 1.00 37.21  ? 862  LEU A N   1 
ATOM   5735 C  CA  . LEU A 1 862 ? 146.073 158.972 180.930 1.00 37.21  ? 862  LEU A CA  1 
ATOM   5736 C  C   . LEU A 1 862 ? 145.558 159.758 182.124 1.00 37.21  ? 862  LEU A C   1 
ATOM   5737 O  O   . LEU A 1 862 ? 144.389 160.151 182.165 1.00 37.21  ? 862  LEU A O   1 
ATOM   5738 C  CB  . LEU A 1 862 ? 146.784 159.919 179.958 1.00 37.21  ? 862  LEU A CB  1 
ATOM   5739 C  CG  . LEU A 1 862 ? 147.364 159.338 178.671 1.00 37.21  ? 862  LEU A CG  1 
ATOM   5740 C  CD1 . LEU A 1 862 ? 147.490 160.419 177.622 1.00 37.21  ? 862  LEU A CD1 1 
ATOM   5741 C  CD2 . LEU A 1 862 ? 148.714 158.727 178.948 1.00 37.21  ? 862  LEU A CD2 1 
ATOM   5742 N  N   . GLN A 1 863 ? 146.426 159.981 183.103 1.00 39.24  ? 863  GLN A N   1 
ATOM   5743 C  CA  . GLN A 1 863 ? 146.063 160.773 184.267 1.00 39.24  ? 863  GLN A CA  1 
ATOM   5744 C  C   . GLN A 1 863 ? 147.173 161.767 184.568 1.00 39.24  ? 863  GLN A C   1 
ATOM   5745 O  O   . GLN A 1 863 ? 148.278 161.681 184.030 1.00 39.24  ? 863  GLN A O   1 
ATOM   5746 C  CB  . GLN A 1 863 ? 145.787 159.894 185.491 1.00 39.24  ? 863  GLN A CB  1 
ATOM   5747 C  CG  . GLN A 1 863 ? 147.020 159.313 186.141 1.00 39.24  ? 863  GLN A CG  1 
ATOM   5748 C  CD  . GLN A 1 863 ? 146.672 158.417 187.308 1.00 39.24  ? 863  GLN A CD  1 
ATOM   5749 O  OE1 . GLN A 1 863 ? 147.550 157.885 187.981 1.00 39.24  ? 863  GLN A OE1 1 
ATOM   5750 N  NE2 . GLN A 1 863 ? 145.379 158.238 187.549 1.00 39.24  ? 863  GLN A NE2 1 
ATOM   5751 N  N   . ALA A 1 864 ? 146.863 162.720 185.441 1.00 35.64  ? 864  ALA A N   1 
ATOM   5752 C  CA  . ALA A 1 864 ? 147.811 163.773 185.766 1.00 35.64  ? 864  ALA A CA  1 
ATOM   5753 C  C   . ALA A 1 864 ? 149.039 163.193 186.453 1.00 35.64  ? 864  ALA A C   1 
ATOM   5754 O  O   . ALA A 1 864 ? 149.007 162.096 187.014 1.00 35.64  ? 864  ALA A O   1 
ATOM   5755 C  CB  . ALA A 1 864 ? 147.155 164.822 186.661 1.00 35.64  ? 864  ALA A CB  1 
ATOM   5756 N  N   . LEU A 1 865 ? 150.135 163.940 186.393 1.00 33.27  ? 865  LEU A N   1 
ATOM   5757 C  CA  . LEU A 1 865 ? 151.377 163.487 186.986 1.00 33.27  ? 865  LEU A CA  1 
ATOM   5758 C  C   . LEU A 1 865 ? 151.805 164.439 188.094 1.00 33.27  ? 865  LEU A C   1 
ATOM   5759 O  O   . LEU A 1 865 ? 151.646 165.656 187.957 1.00 33.27  ? 865  LEU A O   1 
ATOM   5760 C  CB  . LEU A 1 865 ? 152.499 163.399 185.943 1.00 33.27  ? 865  LEU A CB  1 
ATOM   5761 C  CG  . LEU A 1 865 ? 152.485 162.256 184.923 1.00 33.27  ? 865  LEU A CG  1 
ATOM   5762 C  CD1 . LEU A 1 865 ? 151.361 162.422 183.919 1.00 33.27  ? 865  LEU A CD1 1 
ATOM   5763 C  CD2 . LEU A 1 865 ? 153.811 162.156 184.207 1.00 33.27  ? 865  LEU A CD2 1 
ATOM   5764 N  N   . PRO A 1 866 ? 152.337 163.922 189.195 1.00 39.04  ? 866  PRO A N   1 
ATOM   5765 C  CA  . PRO A 1 866 ? 152.797 164.804 190.272 1.00 39.04  ? 866  PRO A CA  1 
ATOM   5766 C  C   . PRO A 1 866 ? 153.994 165.639 189.846 1.00 39.04  ? 866  PRO A C   1 
ATOM   5767 O  O   . PRO A 1 866 ? 154.793 165.238 188.998 1.00 39.04  ? 866  PRO A O   1 
ATOM   5768 C  CB  . PRO A 1 866 ? 153.165 163.830 191.397 1.00 39.04  ? 866  PRO A CB  1 
ATOM   5769 C  CG  . PRO A 1 866 ? 153.433 162.543 190.712 1.00 39.04  ? 866  PRO A CG  1 
ATOM   5770 C  CD  . PRO A 1 866 ? 152.543 162.500 189.510 1.00 39.04  ? 866  PRO A CD  1 
ATOM   5771 N  N   . LEU A 1 867 ? 154.111 166.818 190.462 1.00 41.35  ? 867  LEU A N   1 
ATOM   5772 C  CA  . LEU A 1 867 ? 155.146 167.768 190.064 1.00 41.35  ? 867  LEU A CA  1 
ATOM   5773 C  C   . LEU A 1 867 ? 156.549 167.223 190.301 1.00 41.35  ? 867  LEU A C   1 
ATOM   5774 O  O   . LEU A 1 867 ? 157.509 167.708 189.694 1.00 41.35  ? 867  LEU A O   1 
ATOM   5775 C  CB  . LEU A 1 867 ? 154.961 169.089 190.811 1.00 41.35  ? 867  LEU A CB  1 
ATOM   5776 C  CG  . LEU A 1 867 ? 154.218 170.203 190.070 1.00 41.35  ? 867  LEU A CG  1 
ATOM   5777 C  CD1 . LEU A 1 867 ? 155.023 170.671 188.871 1.00 41.35  ? 867  LEU A CD1 1 
ATOM   5778 C  CD2 . LEU A 1 867 ? 152.828 169.755 189.647 1.00 41.35  ? 867  LEU A CD2 1 
ATOM   5779 N  N   . SER A 1 868 ? 156.693 166.222 191.172 1.00 40.65  ? 868  SER A N   1 
ATOM   5780 C  CA  . SER A 1 868 ? 158.006 165.631 191.408 1.00 40.65  ? 868  SER A CA  1 
ATOM   5781 C  C   . SER A 1 868 ? 158.534 164.884 190.191 1.00 40.65  ? 868  SER A C   1 
ATOM   5782 O  O   . SER A 1 868 ? 159.723 164.553 190.148 1.00 40.65  ? 868  SER A O   1 
ATOM   5783 C  CB  . SER A 1 868 ? 157.956 164.685 192.605 1.00 40.65  ? 868  SER A CB  1 
ATOM   5784 O  OG  . SER A 1 868 ? 159.231 164.116 192.844 1.00 40.65  ? 868  SER A OG  1 
ATOM   5785 N  N   . TYR A 1 869 ? 157.674 164.599 189.213 1.00 35.62  ? 869  TYR A N   1 
ATOM   5786 C  CA  . TYR A 1 869 ? 158.101 163.894 188.011 1.00 35.62  ? 869  TYR A CA  1 
ATOM   5787 C  C   . TYR A 1 869 ? 158.966 164.756 187.105 1.00 35.62  ? 869  TYR A C   1 
ATOM   5788 O  O   . TYR A 1 869 ? 159.940 164.261 186.528 1.00 35.62  ? 869  TYR A O   1 
ATOM   5789 C  CB  . TYR A 1 869 ? 156.874 163.417 187.246 1.00 35.62  ? 869  TYR A CB  1 
ATOM   5790 C  CG  . TYR A 1 869 ? 157.175 162.579 186.032 1.00 35.62  ? 869  TYR A CG  1 
ATOM   5791 C  CD1 . TYR A 1 869 ? 157.555 161.259 186.161 1.00 35.62  ? 869  TYR A CD1 1 
ATOM   5792 C  CD2 . TYR A 1 869 ? 157.056 163.105 184.755 1.00 35.62  ? 869  TYR A CD2 1 
ATOM   5793 C  CE1 . TYR A 1 869 ? 157.823 160.483 185.057 1.00 35.62  ? 869  TYR A CE1 1 
ATOM   5794 C  CE2 . TYR A 1 869 ? 157.316 162.334 183.642 1.00 35.62  ? 869  TYR A CE2 1 
ATOM   5795 C  CZ  . TYR A 1 869 ? 157.698 161.021 183.803 1.00 35.62  ? 869  TYR A CZ  1 
ATOM   5796 O  OH  . TYR A 1 869 ? 157.964 160.232 182.714 1.00 35.62  ? 869  TYR A OH  1 
ATOM   5797 N  N   . PHE A 1 870 ? 158.623 166.033 186.961 1.00 37.39  ? 870  PHE A N   1 
ATOM   5798 C  CA  . PHE A 1 870 ? 159.211 166.853 185.903 1.00 37.39  ? 870  PHE A CA  1 
ATOM   5799 C  C   . PHE A 1 870 ? 160.720 167.021 186.030 1.00 37.39  ? 870  PHE A C   1 
ATOM   5800 O  O   . PHE A 1 870 ? 161.410 166.954 184.997 1.00 37.39  ? 870  PHE A O   1 
ATOM   5801 C  CB  . PHE A 1 870 ? 158.485 168.200 185.848 1.00 37.39  ? 870  PHE A CB  1 
ATOM   5802 C  CG  . PHE A 1 870 ? 157.079 168.105 185.326 1.00 37.39  ? 870  PHE A CG  1 
ATOM   5803 C  CD1 . PHE A 1 870 ? 156.560 166.893 184.906 1.00 37.39  ? 870  PHE A CD1 1 
ATOM   5804 C  CD2 . PHE A 1 870 ? 156.275 169.227 185.258 1.00 37.39  ? 870  PHE A CD2 1 
ATOM   5805 C  CE1 . PHE A 1 870 ? 155.271 166.801 184.431 1.00 37.39  ? 870  PHE A CE1 1 
ATOM   5806 C  CE2 . PHE A 1 870 ? 154.984 169.140 184.782 1.00 37.39  ? 870  PHE A CE2 1 
ATOM   5807 C  CZ  . PHE A 1 870 ? 154.482 167.925 184.368 1.00 37.39  ? 870  PHE A CZ  1 
ATOM   5808 N  N   . PRO A 1 871 ? 161.297 167.269 187.212 1.00 38.90  ? 871  PRO A N   1 
ATOM   5809 C  CA  . PRO A 1 871 ? 162.768 167.269 187.291 1.00 38.90  ? 871  PRO A CA  1 
ATOM   5810 C  C   . PRO A 1 871 ? 163.390 165.954 186.859 1.00 38.90  ? 871  PRO A C   1 
ATOM   5811 O  O   . PRO A 1 871 ? 164.420 165.952 186.173 1.00 38.90  ? 871  PRO A O   1 
ATOM   5812 C  CB  . PRO A 1 871 ? 163.033 167.570 188.771 1.00 38.90  ? 871  PRO A CB  1 
ATOM   5813 C  CG  . PRO A 1 871 ? 161.833 168.328 189.212 1.00 38.90  ? 871  PRO A CG  1 
ATOM   5814 C  CD  . PRO A 1 871 ? 160.686 167.705 188.481 1.00 38.90  ? 871  PRO A CD  1 
ATOM   5815 N  N   . TRP A 1 872 ? 162.777 164.827 187.227 1.00 37.53  ? 872  TRP A N   1 
ATOM   5816 C  CA  . TRP A 1 872 ? 163.285 163.532 186.786 1.00 37.53  ? 872  TRP A CA  1 
ATOM   5817 C  C   . TRP A 1 872 ? 163.189 163.394 185.274 1.00 37.53  ? 872  TRP A C   1 
ATOM   5818 O  O   . TRP A 1 872 ? 164.099 162.859 184.631 1.00 37.53  ? 872  TRP A O   1 
ATOM   5819 C  CB  . TRP A 1 872 ? 162.519 162.406 187.476 1.00 37.53  ? 872  TRP A CB  1 
ATOM   5820 C  CG  . TRP A 1 872 ? 162.882 162.223 188.912 1.00 37.53  ? 872  TRP A CG  1 
ATOM   5821 C  CD1 . TRP A 1 872 ? 162.100 162.490 189.994 1.00 37.53  ? 872  TRP A CD1 1 
ATOM   5822 C  CD2 . TRP A 1 872 ? 164.122 161.727 189.427 1.00 37.53  ? 872  TRP A CD2 1 
ATOM   5823 N  NE1 . TRP A 1 872 ? 162.775 162.194 191.152 1.00 37.53  ? 872  TRP A NE1 1 
ATOM   5824 C  CE2 . TRP A 1 872 ? 164.020 161.723 190.830 1.00 37.53  ? 872  TRP A CE2 1 
ATOM   5825 C  CE3 . TRP A 1 872 ? 165.309 161.285 188.836 1.00 37.53  ? 872  TRP A CE3 1 
ATOM   5826 C  CZ2 . TRP A 1 872 ? 165.058 161.297 191.653 1.00 37.53  ? 872  TRP A CZ2 1 
ATOM   5827 C  CZ3 . TRP A 1 872 ? 166.339 160.862 189.655 1.00 37.53  ? 872  TRP A CZ3 1 
ATOM   5828 C  CH2 . TRP A 1 872 ? 166.207 160.871 191.047 1.00 37.53  ? 872  TRP A CH2 1 
ATOM   5829 N  N   . LEU A 1 873 ? 162.087 163.867 184.691 1.00 34.81  ? 873  LEU A N   1 
ATOM   5830 C  CA  . LEU A 1 873 ? 161.943 163.860 183.240 1.00 34.81  ? 873  LEU A CA  1 
ATOM   5831 C  C   . LEU A 1 873 ? 163.058 164.654 182.577 1.00 34.81  ? 873  LEU A C   1 
ATOM   5832 O  O   . LEU A 1 873 ? 163.671 164.195 181.605 1.00 34.81  ? 873  LEU A O   1 
ATOM   5833 C  CB  . LEU A 1 873 ? 160.575 164.431 182.864 1.00 34.81  ? 873  LEU A CB  1 
ATOM   5834 C  CG  . LEU A 1 873 ? 160.254 164.738 181.405 1.00 34.81  ? 873  LEU A CG  1 
ATOM   5835 C  CD1 . LEU A 1 873 ? 158.818 164.396 181.138 1.00 34.81  ? 873  LEU A CD1 1 
ATOM   5836 C  CD2 . LEU A 1 873 ? 160.491 166.203 181.111 1.00 34.81  ? 873  LEU A CD2 1 
ATOM   5837 N  N   . VAL A 1 874 ? 163.329 165.856 183.088 1.00 35.32  ? 874  VAL A N   1 
ATOM   5838 C  CA  . VAL A 1 874 ? 164.363 166.698 182.496 1.00 35.32  ? 874  VAL A CA  1 
ATOM   5839 C  C   . VAL A 1 874 ? 165.724 166.027 182.613 1.00 35.32  ? 874  VAL A C   1 
ATOM   5840 O  O   . VAL A 1 874 ? 166.524 166.042 181.669 1.00 35.32  ? 874  VAL A O   1 
ATOM   5841 C  CB  . VAL A 1 874 ? 164.357 168.091 183.149 1.00 35.32  ? 874  VAL A CB  1 
ATOM   5842 C  CG1 . VAL A 1 874 ? 165.555 168.897 182.689 1.00 35.32  ? 874  VAL A CG1 1 
ATOM   5843 C  CG2 . VAL A 1 874 ? 163.065 168.817 182.822 1.00 35.32  ? 874  VAL A CG2 1 
ATOM   5844 N  N   . ALA A 1 875 ? 166.007 165.425 183.770 1.00 35.34  ? 875  ALA A N   1 
ATOM   5845 C  CA  . ALA A 1 875 ? 167.275 164.726 183.943 1.00 35.34  ? 875  ALA A CA  1 
ATOM   5846 C  C   . ALA A 1 875 ? 167.407 163.568 182.962 1.00 35.34  ? 875  ALA A C   1 
ATOM   5847 O  O   . ALA A 1 875 ? 168.467 163.377 182.355 1.00 35.34  ? 875  ALA A O   1 
ATOM   5848 C  CB  . ALA A 1 875 ? 167.409 164.228 185.381 1.00 35.34  ? 875  ALA A CB  1 
ATOM   5849 N  N   . ILE A 1 876 ? 166.335 162.791 182.785 1.00 32.33  ? 876  ILE A N   1 
ATOM   5850 C  CA  . ILE A 1 876 ? 166.385 161.657 181.867 1.00 32.33  ? 876  ILE A CA  1 
ATOM   5851 C  C   . ILE A 1 876 ? 166.625 162.135 180.443 1.00 32.33  ? 876  ILE A C   1 
ATOM   5852 O  O   . ILE A 1 876 ? 167.446 161.567 179.713 1.00 32.33  ? 876  ILE A O   1 
ATOM   5853 C  CB  . ILE A 1 876 ? 165.096 160.822 181.967 1.00 32.33  ? 876  ILE A CB  1 
ATOM   5854 C  CG1 . ILE A 1 876 ? 165.031 160.092 183.305 1.00 32.33  ? 876  ILE A CG1 1 
ATOM   5855 C  CG2 . ILE A 1 876 ? 165.030 159.813 180.838 1.00 32.33  ? 876  ILE A CG2 1 
ATOM   5856 C  CD1 . ILE A 1 876 ? 163.724 159.378 183.534 1.00 32.33  ? 876  ILE A CD1 1 
ATOM   5857 N  N   . LEU A 1 877 ? 165.914 163.183 180.023 1.00 31.58  ? 877  LEU A N   1 
ATOM   5858 C  CA  . LEU A 1 877 ? 166.071 163.677 178.659 1.00 31.58  ? 877  LEU A CA  1 
ATOM   5859 C  C   . LEU A 1 877 ? 167.475 164.216 178.428 1.00 31.58  ? 877  LEU A C   1 
ATOM   5860 O  O   . LEU A 1 877 ? 168.095 163.943 177.393 1.00 31.58  ? 877  LEU A O   1 
ATOM   5861 C  CB  . LEU A 1 877 ? 165.034 164.754 178.358 1.00 31.58  ? 877  LEU A CB  1 
ATOM   5862 C  CG  . LEU A 1 877 ? 163.578 164.307 178.370 1.00 31.58  ? 877  LEU A CG  1 
ATOM   5863 C  CD1 . LEU A 1 877 ? 162.678 165.500 178.161 1.00 31.58  ? 877  LEU A CD1 1 
ATOM   5864 C  CD2 . LEU A 1 877 ? 163.338 163.258 177.317 1.00 31.58  ? 877  LEU A CD2 1 
ATOM   5865 N  N   . ALA A 1 878 ? 167.994 164.994 179.380 1.00 35.54  ? 878  ALA A N   1 
ATOM   5866 C  CA  . ALA A 1 878 ? 169.338 165.536 179.227 1.00 35.54  ? 878  ALA A CA  1 
ATOM   5867 C  C   . ALA A 1 878 ? 170.370 164.422 179.163 1.00 35.54  ? 878  ALA A C   1 
ATOM   5868 O  O   . ALA A 1 878 ? 171.288 164.463 178.334 1.00 35.54  ? 878  ALA A O   1 
ATOM   5869 C  CB  . ALA A 1 878 ? 169.653 166.498 180.370 1.00 35.54  ? 878  ALA A CB  1 
ATOM   5870 N  N   . GLY A 1 879 ? 170.233 163.412 180.025 1.00 35.19  ? 879  GLY A N   1 
ATOM   5871 C  CA  . GLY A 1 879 ? 171.152 162.291 179.982 1.00 35.19  ? 879  GLY A CA  1 
ATOM   5872 C  C   . GLY A 1 879 ? 171.088 161.540 178.668 1.00 35.19  ? 879  GLY A C   1 
ATOM   5873 O  O   . GLY A 1 879 ? 172.118 161.163 178.106 1.00 35.19  ? 879  GLY A O   1 
ATOM   5874 N  N   . TYR A 1 880 ? 169.877 161.316 178.158 1.00 33.44  ? 880  TYR A N   1 
ATOM   5875 C  CA  . TYR A 1 880 ? 169.726 160.621 176.886 1.00 33.44  ? 880  TYR A CA  1 
ATOM   5876 C  C   . TYR A 1 880 ? 170.377 161.407 175.756 1.00 33.44  ? 880  TYR A C   1 
ATOM   5877 O  O   . TYR A 1 880 ? 171.109 160.837 174.933 1.00 33.44  ? 880  TYR A O   1 
ATOM   5878 C  CB  . TYR A 1 880 ? 168.241 160.375 176.620 1.00 33.44  ? 880  TYR A CB  1 
ATOM   5879 C  CG  . TYR A 1 880 ? 167.909 159.769 175.281 1.00 33.44  ? 880  TYR A CG  1 
ATOM   5880 C  CD1 . TYR A 1 880 ? 168.631 158.698 174.784 1.00 33.44  ? 880  TYR A CD1 1 
ATOM   5881 C  CD2 . TYR A 1 880 ? 166.836 160.235 174.540 1.00 33.44  ? 880  TYR A CD2 1 
ATOM   5882 C  CE1 . TYR A 1 880 ? 168.319 158.134 173.568 1.00 33.44  ? 880  TYR A CE1 1 
ATOM   5883 C  CE2 . TYR A 1 880 ? 166.512 159.674 173.328 1.00 33.44  ? 880  TYR A CE2 1 
ATOM   5884 C  CZ  . TYR A 1 880 ? 167.259 158.626 172.844 1.00 33.44  ? 880  TYR A CZ  1 
ATOM   5885 O  OH  . TYR A 1 880 ? 166.941 158.062 171.632 1.00 33.44  ? 880  TYR A OH  1 
ATOM   5886 N  N   . MET A 1 881 ? 170.162 162.724 175.731 1.00 34.73  ? 881  MET A N   1 
ATOM   5887 C  CA  . MET A 1 881 ? 170.800 163.562 174.721 1.00 34.73  ? 881  MET A CA  1 
ATOM   5888 C  C   . MET A 1 881 ? 172.318 163.469 174.796 1.00 34.73  ? 881  MET A C   1 
ATOM   5889 O  O   . MET A 1 881 ? 172.982 163.224 173.782 1.00 34.73  ? 881  MET A O   1 
ATOM   5890 C  CB  . MET A 1 881 ? 170.359 165.015 174.874 1.00 34.73  ? 881  MET A CB  1 
ATOM   5891 C  CG  . MET A 1 881 ? 168.974 165.332 174.369 1.00 34.73  ? 881  MET A CG  1 
ATOM   5892 S  SD  . MET A 1 881 ? 169.008 166.992 173.674 1.00 34.73  ? 881  MET A SD  1 
ATOM   5893 C  CE  . MET A 1 881 ? 167.281 167.280 173.362 1.00 34.73  ? 881  MET A CE  1 
ATOM   5894 N  N   . THR A 1 882 ? 172.896 163.677 175.983 1.00 35.73  ? 882  THR A N   1 
ATOM   5895 C  CA  . THR A 1 882 ? 174.355 163.713 176.047 1.00 35.73  ? 882  THR A CA  1 
ATOM   5896 C  C   . THR A 1 882 ? 174.947 162.350 175.722 1.00 35.73  ? 882  THR A C   1 
ATOM   5897 O  O   . THR A 1 882 ? 175.965 162.259 175.026 1.00 35.73  ? 882  THR A O   1 
ATOM   5898 C  CB  . THR A 1 882 ? 174.853 164.194 177.411 1.00 35.73  ? 882  THR A CB  1 
ATOM   5899 O  OG1 . THR A 1 882 ? 176.251 163.903 177.527 1.00 35.73  ? 882  THR A OG1 1 
ATOM   5900 C  CG2 . THR A 1 882 ? 174.148 163.484 178.532 1.00 35.73  ? 882  THR A CG2 1 
ATOM   5901 N  N   . LEU A 1 883 ? 174.293 161.287 176.161 1.00 33.47  ? 883  LEU A N   1 
ATOM   5902 C  CA  . LEU A 1 883 ? 174.811 159.962 175.915 1.00 33.47  ? 883  LEU A CA  1 
ATOM   5903 C  C   . LEU A 1 883 ? 174.775 159.659 174.438 1.00 33.47  ? 883  LEU A C   1 
ATOM   5904 O  O   . LEU A 1 883 ? 175.776 159.247 173.867 1.00 33.47  ? 883  LEU A O   1 
ATOM   5905 C  CB  . LEU A 1 883 ? 174.017 158.921 176.687 1.00 33.47  ? 883  LEU A CB  1 
ATOM   5906 C  CG  . LEU A 1 883 ? 174.782 157.642 176.990 1.00 33.47  ? 883  LEU A CG  1 
ATOM   5907 C  CD1 . LEU A 1 883 ? 173.963 156.741 177.891 1.00 33.47  ? 883  LEU A CD1 1 
ATOM   5908 C  CD2 . LEU A 1 883 ? 175.156 156.924 175.711 1.00 33.47  ? 883  LEU A CD2 1 
ATOM   5909 N  N   . THR A 1 884 ? 173.632 159.899 173.808 1.00 35.21  ? 884  THR A N   1 
ATOM   5910 C  CA  . THR A 1 884 ? 173.495 159.602 172.388 1.00 35.21  ? 884  THR A CA  1 
ATOM   5911 C  C   . THR A 1 884 ? 174.445 160.412 171.528 1.00 35.21  ? 884  THR A C   1 
ATOM   5912 O  O   . THR A 1 884 ? 174.951 159.914 170.536 1.00 35.21  ? 884  THR A O   1 
ATOM   5913 C  CB  . THR A 1 884 ? 172.058 159.738 171.871 1.00 35.21  ? 884  THR A CB  1 
ATOM   5914 O  OG1 . THR A 1 884 ? 172.061 159.577 170.451 1.00 35.21  ? 884  THR A OG1 1 
ATOM   5915 C  CG2 . THR A 1 884 ? 171.492 161.093 172.207 1.00 35.21  ? 884  THR A CG2 1 
ATOM   5916 N  N   . GLN A 1 885 ? 174.666 161.673 171.866 1.00 40.37  ? 885  GLN A N   1 
ATOM   5917 C  CA  . GLN A 1 885 ? 175.594 162.459 171.078 1.00 40.37  ? 885  GLN A CA  1 
ATOM   5918 C  C   . GLN A 1 885 ? 176.993 161.870 171.186 1.00 40.37  ? 885  GLN A C   1 
ATOM   5919 O  O   . GLN A 1 885 ? 177.712 161.809 170.201 1.00 40.37  ? 885  GLN A O   1 
ATOM   5920 C  CB  . GLN A 1 885 ? 175.598 163.916 171.527 1.00 40.37  ? 885  GLN A CB  1 
ATOM   5921 C  CG  . GLN A 1 885 ? 176.517 164.805 170.712 1.00 40.37  ? 885  GLN A CG  1 
ATOM   5922 C  CD  . GLN A 1 885 ? 177.979 164.538 170.993 1.00 40.37  ? 885  GLN A CD  1 
ATOM   5923 O  OE1 . GLN A 1 885 ? 178.334 164.045 172.059 1.00 40.37  ? 885  GLN A OE1 1 
ATOM   5924 N  NE2 . GLN A 1 885 ? 178.836 164.863 170.037 1.00 40.37  ? 885  GLN A NE2 1 
ATOM   5925 N  N   . LEU A 1 886 ? 177.391 161.466 172.390 1.00 39.52  ? 886  LEU A N   1 
ATOM   5926 C  CA  . LEU A 1 886 ? 178.716 160.888 172.602 1.00 39.52  ? 886  LEU A CA  1 
ATOM   5927 C  C   . LEU A 1 886 ? 178.930 159.570 171.878 1.00 39.52  ? 886  LEU A C   1 
ATOM   5928 O  O   . LEU A 1 886 ? 179.967 159.349 171.265 1.00 39.52  ? 886  LEU A O   1 
ATOM   5929 C  CB  . LEU A 1 886 ? 178.965 160.673 174.090 1.00 39.52  ? 886  LEU A CB  1 
ATOM   5930 C  CG  . LEU A 1 886 ? 179.163 161.938 174.911 1.00 39.52  ? 886  LEU A CG  1 
ATOM   5931 C  CD1 . LEU A 1 886 ? 179.466 161.576 176.352 1.00 39.52  ? 886  LEU A CD1 1 
ATOM   5932 C  CD2 . LEU A 1 886 ? 180.277 162.772 174.310 1.00 39.52  ? 886  LEU A CD2 1 
ATOM   5933 N  N   . VAL A 1 887 ? 177.944 158.693 171.958 1.00 37.77  ? 887  VAL A N   1 
ATOM   5934 C  CA  . VAL A 1 887 ? 178.025 157.405 171.297 1.00 37.77  ? 887  VAL A CA  1 
ATOM   5935 C  C   . VAL A 1 887 ? 178.050 157.527 169.786 1.00 37.77  ? 887  VAL A C   1 
ATOM   5936 O  O   . VAL A 1 887 ? 178.685 156.726 169.110 1.00 37.77  ? 887  VAL A O   1 
ATOM   5937 C  CB  . VAL A 1 887 ? 176.899 156.469 171.716 1.00 37.77  ? 887  VAL A CB  1 
ATOM   5938 C  CG1 . VAL A 1 887 ? 176.721 155.382 170.673 1.00 37.77  ? 887  VAL A CG1 1 
ATOM   5939 C  CG2 . VAL A 1 887 ? 177.220 155.870 173.069 1.00 37.77  ? 887  VAL A CG2 1 
ATOM   5940 N  N   . LYS A 1 888 ? 177.291 158.498 169.282 1.00 41.16  ? 888  LYS A N   1 
ATOM   5941 C  CA  . LYS A 1 888 ? 177.142 158.786 167.855 1.00 41.16  ? 888  LYS A CA  1 
ATOM   5942 C  C   . LYS A 1 888 ? 178.410 158.621 167.037 1.00 41.16  ? 888  LYS A C   1 
ATOM   5943 O  O   . LYS A 1 888 ? 178.369 158.113 165.922 1.00 41.16  ? 888  LYS A O   1 
ATOM   5944 C  CB  . LYS A 1 888 ? 176.575 160.191 167.664 1.00 41.16  ? 888  LYS A CB  1 
ATOM   5945 C  CG  . LYS A 1 888 ? 176.217 160.527 166.233 1.00 41.16  ? 888  LYS A CG  1 
ATOM   5946 C  CD  . LYS A 1 888 ? 175.439 161.827 166.156 1.00 41.16  ? 888  LYS A CD  1 
ATOM   5947 C  CE  . LYS A 1 888 ? 176.177 162.958 166.846 1.00 41.16  ? 888  LYS A CE  1 
ATOM   5948 N  NZ  . LYS A 1 888 ? 175.410 164.231 166.798 1.00 41.16  ? 888  LYS A NZ  1 
ATOM   5949 N  N   . GLY A 1 889 ? 179.545 159.013 167.600 1.00 47.74  ? 889  GLY A N   1 
ATOM   5950 C  CA  . GLY A 1 889 ? 180.788 158.869 166.864 1.00 47.74  ? 889  GLY A CA  1 
ATOM   5951 C  C   . GLY A 1 889 ? 181.229 157.440 166.636 1.00 47.74  ? 889  GLY A C   1 
ATOM   5952 O  O   . GLY A 1 889 ? 182.278 157.229 166.019 1.00 47.74  ? 889  GLY A O   1 
ATOM   5953 N  N   . PHE A 1 890 ? 180.471 156.463 167.121 1.00 48.74  ? 890  PHE A N   1 
ATOM   5954 C  CA  . PHE A 1 890 ? 180.856 155.065 167.012 1.00 48.74  ? 890  PHE A CA  1 
ATOM   5955 C  C   . PHE A 1 890 ? 180.230 154.359 165.820 1.00 48.74  ? 890  PHE A C   1 
ATOM   5956 O  O   . PHE A 1 890 ? 180.354 153.134 165.711 1.00 48.74  ? 890  PHE A O   1 
ATOM   5957 C  CB  . PHE A 1 890 ? 180.499 154.324 168.298 1.00 48.74  ? 890  PHE A CB  1 
ATOM   5958 C  CG  . PHE A 1 890 ? 181.580 154.359 169.330 1.00 48.74  ? 890  PHE A CG  1 
ATOM   5959 C  CD1 . PHE A 1 890 ? 181.499 153.568 170.460 1.00 48.74  ? 890  PHE A CD1 1 
ATOM   5960 C  CD2 . PHE A 1 890 ? 182.687 155.170 169.163 1.00 48.74  ? 890  PHE A CD2 1 
ATOM   5961 C  CE1 . PHE A 1 890 ? 182.495 153.592 171.411 1.00 48.74  ? 890  PHE A CE1 1 
ATOM   5962 C  CE2 . PHE A 1 890 ? 183.688 155.198 170.109 1.00 48.74  ? 890  PHE A CE2 1 
ATOM   5963 C  CZ  . PHE A 1 890 ? 183.591 154.408 171.235 1.00 48.74  ? 890  PHE A CZ  1 
ATOM   5964 N  N   . TYR A 1 891 ? 179.544 155.089 164.941 1.00 51.89  ? 891  TYR A N   1 
ATOM   5965 C  CA  . TYR A 1 891 ? 179.016 154.471 163.730 1.00 51.89  ? 891  TYR A CA  1 
ATOM   5966 C  C   . TYR A 1 891 ? 180.135 153.999 162.810 1.00 51.89  ? 891  TYR A C   1 
ATOM   5967 O  O   . TYR A 1 891 ? 180.104 152.864 162.320 1.00 51.89  ? 891  TYR A O   1 
ATOM   5968 C  CB  . TYR A 1 891 ? 178.092 155.447 163.006 1.00 51.89  ? 891  TYR A CB  1 
ATOM   5969 C  CG  . TYR A 1 891 ? 176.914 154.768 162.360 1.00 51.89  ? 891  TYR A CG  1 
ATOM   5970 C  CD1 . TYR A 1 891 ? 176.122 153.885 163.074 1.00 51.89  ? 891  TYR A CD1 1 
ATOM   5971 C  CD2 . TYR A 1 891 ? 176.604 155.000 161.029 1.00 51.89  ? 891  TYR A CD2 1 
ATOM   5972 C  CE1 . TYR A 1 891 ? 175.055 153.257 162.484 1.00 51.89  ? 891  TYR A CE1 1 
ATOM   5973 C  CE2 . TYR A 1 891 ? 175.539 154.381 160.433 1.00 51.89  ? 891  TYR A CE2 1 
ATOM   5974 C  CZ  . TYR A 1 891 ? 174.767 153.510 161.163 1.00 51.89  ? 891  TYR A CZ  1 
ATOM   5975 O  OH  . TYR A 1 891 ? 173.704 152.892 160.556 1.00 51.89  ? 891  TYR A OH  1 
ATOM   5976 N  N   . SER A 1 892 ? 181.142 154.838 162.587 1.00 57.91  ? 892  SER A N   1 
ATOM   5977 C  CA  . SER A 1 892 ? 182.240 154.501 161.686 1.00 57.91  ? 892  SER A CA  1 
ATOM   5978 C  C   . SER A 1 892 ? 183.183 153.468 162.298 1.00 57.91  ? 892  SER A C   1 
ATOM   5979 O  O   . SER A 1 892 ? 183.759 153.687 163.364 1.00 57.91  ? 892  SER A O   1 
ATOM   5980 C  CB  . SER A 1 892 ? 183.023 155.758 161.305 1.00 57.91  ? 892  SER A CB  1 
ATOM   5981 O  OG  . SER A 1 892 ? 183.754 156.257 162.411 1.00 57.91  ? 892  SER A OG  1 
HETATM 5982 MG MG  . MG  B 2 .   ? 161.850 156.046 173.055 1.00 53.08  ? 1001 MG  A MG  1 
# 
