data_8UUS
# 
_entry.id   8UUS 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UUS         pdb_00008uus 10.2210/pdb8uus/pdb 
WWPDB D_1000278667 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UUS 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              mark.hurst@agresearch.co.nz 
_pdbx_contact_author.name_first         Mark 
_pdbx_contact_author.name_last          Hurst 
_pdbx_contact_author.name_mi            'R. H.' 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5826-5253 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Young, P.G.'   1 0000-0002-7325-1869 
'Hurst, M.R.H.' 2 0000-0001-5826-5253 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structure of Serratia entomophila antifeeding prophage Fibre foot domain (Afp13)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Young, P.G.'   1 0000-0002-7325-1869 
primary 'Hurst, M.R.H.' 2 0000-0001-5826-5253 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Antifeeding Prophage (Tailocin) fibre' 17052.398 3   ? ? 'foot domain' ? 
2 non-polymer syn 'AMMONIUM ION'                          18.038    1   ? ? ?             ? 
3 non-polymer syn GLYCEROL                                92.094    3   ? ? ?             ? 
4 non-polymer syn 'CITRIC ACID'                           192.124   1   ? ? ?             ? 
5 water       nat water                                   18.015    274 ? ? ?             ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        AfpX13 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;GAKVEASKGLQVTASGVSVQAGDGISVAGTGVAVKVEASKGLQVTSNGVGLNNTAWIKMMCGLHNATFYVSDTYVCVFFC
NHSTGCTAYVYGRGGYYLSMYKGDVKLNSVDHNEIISMVGSGSIAAATMVSWKSTKAAAGISFKYLGKNLITSTSHSGSV
TLVAAP
;
_entity_poly.pdbx_seq_one_letter_code_can   
;GAKVEASKGLQVTASGVSVQAGDGISVAGTGVAVKVEASKGLQVTSNGVGLNNTAWIKMMCGLHNATFYVSDTYVCVFFC
NHSTGCTAYVYGRGGYYLSMYKGDVKLNSVDHNEIISMVGSGSIAAATMVSWKSTKAAAGISFKYLGKNLITSTSHSGSV
TLVAAP
;
_entity_poly.pdbx_strand_id                 A,B,C 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'AMMONIUM ION' NH4 
3 GLYCEROL       GOL 
4 'CITRIC ACID'  CIT 
5 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   ALA n 
1 3   LYS n 
1 4   VAL n 
1 5   GLU n 
1 6   ALA n 
1 7   SER n 
1 8   LYS n 
1 9   GLY n 
1 10  LEU n 
1 11  GLN n 
1 12  VAL n 
1 13  THR n 
1 14  ALA n 
1 15  SER n 
1 16  GLY n 
1 17  VAL n 
1 18  SER n 
1 19  VAL n 
1 20  GLN n 
1 21  ALA n 
1 22  GLY n 
1 23  ASP n 
1 24  GLY n 
1 25  ILE n 
1 26  SER n 
1 27  VAL n 
1 28  ALA n 
1 29  GLY n 
1 30  THR n 
1 31  GLY n 
1 32  VAL n 
1 33  ALA n 
1 34  VAL n 
1 35  LYS n 
1 36  VAL n 
1 37  GLU n 
1 38  ALA n 
1 39  SER n 
1 40  LYS n 
1 41  GLY n 
1 42  LEU n 
1 43  GLN n 
1 44  VAL n 
1 45  THR n 
1 46  SER n 
1 47  ASN n 
1 48  GLY n 
1 49  VAL n 
1 50  GLY n 
1 51  LEU n 
1 52  ASN n 
1 53  ASN n 
1 54  THR n 
1 55  ALA n 
1 56  TRP n 
1 57  ILE n 
1 58  LYS n 
1 59  MET n 
1 60  MET n 
1 61  CYS n 
1 62  GLY n 
1 63  LEU n 
1 64  HIS n 
1 65  ASN n 
1 66  ALA n 
1 67  THR n 
1 68  PHE n 
1 69  TYR n 
1 70  VAL n 
1 71  SER n 
1 72  ASP n 
1 73  THR n 
1 74  TYR n 
1 75  VAL n 
1 76  CYS n 
1 77  VAL n 
1 78  PHE n 
1 79  PHE n 
1 80  CYS n 
1 81  ASN n 
1 82  HIS n 
1 83  SER n 
1 84  THR n 
1 85  GLY n 
1 86  CYS n 
1 87  THR n 
1 88  ALA n 
1 89  TYR n 
1 90  VAL n 
1 91  TYR n 
1 92  GLY n 
1 93  ARG n 
1 94  GLY n 
1 95  GLY n 
1 96  TYR n 
1 97  TYR n 
1 98  LEU n 
1 99  SER n 
1 100 MET n 
1 101 TYR n 
1 102 LYS n 
1 103 GLY n 
1 104 ASP n 
1 105 VAL n 
1 106 LYS n 
1 107 LEU n 
1 108 ASN n 
1 109 SER n 
1 110 VAL n 
1 111 ASP n 
1 112 HIS n 
1 113 ASN n 
1 114 GLU n 
1 115 ILE n 
1 116 ILE n 
1 117 SER n 
1 118 MET n 
1 119 VAL n 
1 120 GLY n 
1 121 SER n 
1 122 GLY n 
1 123 SER n 
1 124 ILE n 
1 125 ALA n 
1 126 ALA n 
1 127 ALA n 
1 128 THR n 
1 129 MET n 
1 130 VAL n 
1 131 SER n 
1 132 TRP n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 LYS n 
1 137 ALA n 
1 138 ALA n 
1 139 ALA n 
1 140 GLY n 
1 141 ILE n 
1 142 SER n 
1 143 PHE n 
1 144 LYS n 
1 145 TYR n 
1 146 LEU n 
1 147 GLY n 
1 148 LYS n 
1 149 ASN n 
1 150 LEU n 
1 151 ILE n 
1 152 THR n 
1 153 SER n 
1 154 THR n 
1 155 SER n 
1 156 HIS n 
1 157 SER n 
1 158 GLY n 
1 159 SER n 
1 160 VAL n 
1 161 THR n 
1 162 LEU n 
1 163 VAL n 
1 164 ALA n 
1 165 ALA n 
1 166 PRO n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   166 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    AGR96X 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Serratia proteamaculans' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     28151 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli K-12' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     83333 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'Shuffle T7' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?                               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?                               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?                               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                               'C4 H7 N O4'     133.103 
CIT non-polymer         . 'CITRIC ACID'   ?                               'C6 H8 O7'       192.124 
CYS 'L-peptide linking' y CYSTEINE        ?                               'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?                               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?                               'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL        'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE       ?                               'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ?                               'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ?                               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?                               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?                               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?                               'C5 H11 N O2 S'  149.211 
NH4 non-polymer         . 'AMMONIUM ION'  ?                               'H4 N 1'         18.038  
PHE 'L-peptide linking' y PHENYLALANINE   ?                               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?                               'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ?                               'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ?                               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?                               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?                               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?                               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   LYS 3   3   3   LYS LYS A . n 
A 1 4   VAL 4   4   4   VAL VAL A . n 
A 1 5   GLU 5   5   5   GLU GLU A . n 
A 1 6   ALA 6   6   6   ALA ALA A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   LYS 8   8   8   LYS LYS A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  GLN 11  11  11  GLN GLN A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  THR 13  13  13  THR THR A . n 
A 1 14  ALA 14  14  14  ALA ALA A . n 
A 1 15  SER 15  15  15  SER SER A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  SER 18  18  18  SER SER A . n 
A 1 19  VAL 19  19  19  VAL VAL A . n 
A 1 20  GLN 20  20  20  GLN GLN A . n 
A 1 21  ALA 21  21  21  ALA ALA A . n 
A 1 22  GLY 22  22  22  GLY GLY A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  ILE 25  25  25  ILE ILE A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  VAL 27  27  27  VAL VAL A . n 
A 1 28  ALA 28  28  28  ALA ALA A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  VAL 32  32  32  VAL VAL A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  LYS 35  35  35  LYS LYS A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  GLU 37  37  37  GLU GLU A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  SER 39  39  39  SER SER A . n 
A 1 40  LYS 40  40  40  LYS LYS A . n 
A 1 41  GLY 41  41  41  GLY GLY A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  GLN 43  43  43  GLN GLN A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  VAL 49  49  49  VAL VAL A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  ASN 52  52  52  ASN ASN A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  THR 54  54  54  THR THR A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  TRP 56  56  56  TRP TRP A . n 
A 1 57  ILE 57  57  57  ILE ILE A . n 
A 1 58  LYS 58  58  58  LYS LYS A . n 
A 1 59  MET 59  59  59  MET MET A . n 
A 1 60  MET 60  60  60  MET MET A . n 
A 1 61  CYS 61  61  61  CYS CYS A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  LEU 63  63  63  LEU LEU A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  ALA 66  66  66  ALA ALA A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  PHE 68  68  68  PHE PHE A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  SER 71  71  71  SER SER A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  THR 73  73  73  THR THR A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  CYS 76  76  76  CYS CYS A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  PHE 78  78  78  PHE PHE A . n 
A 1 79  PHE 79  79  79  PHE PHE A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  ASN 81  81  81  ASN ASN A . n 
A 1 82  HIS 82  82  82  HIS HIS A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  GLY 85  85  85  GLY GLY A . n 
A 1 86  CYS 86  86  86  CYS CYS A . n 
A 1 87  THR 87  87  87  THR THR A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  TYR 89  89  89  TYR TYR A . n 
A 1 90  VAL 90  90  90  VAL VAL A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  GLY 92  92  92  GLY GLY A . n 
A 1 93  ARG 93  93  93  ARG ARG A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  GLY 95  95  95  GLY GLY A . n 
A 1 96  TYR 96  96  96  TYR TYR A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 MET 100 100 100 MET MET A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 GLY 103 103 103 GLY GLY A . n 
A 1 104 ASP 104 104 104 ASP ASP A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 LYS 106 106 106 LYS LYS A . n 
A 1 107 LEU 107 107 107 LEU LEU A . n 
A 1 108 ASN 108 108 108 ASN ASN A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 VAL 110 110 110 VAL VAL A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 HIS 112 112 112 HIS HIS A . n 
A 1 113 ASN 113 113 113 ASN ASN A . n 
A 1 114 GLU 114 114 114 GLU GLU A . n 
A 1 115 ILE 115 115 115 ILE ILE A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 SER 117 117 117 SER SER A . n 
A 1 118 MET 118 118 118 MET MET A . n 
A 1 119 VAL 119 119 119 VAL VAL A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 SER 121 121 ?   ?   ?   A . n 
A 1 122 GLY 122 122 ?   ?   ?   A . n 
A 1 123 SER 123 123 ?   ?   ?   A . n 
A 1 124 ILE 124 124 124 ILE ILE A . n 
A 1 125 ALA 125 125 125 ALA ALA A . n 
A 1 126 ALA 126 126 126 ALA ALA A . n 
A 1 127 ALA 127 127 127 ALA ALA A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 MET 129 129 129 MET MET A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 SER 131 131 131 SER SER A . n 
A 1 132 TRP 132 132 132 TRP TRP A . n 
A 1 133 LYS 133 133 133 LYS LYS A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 LYS 136 136 136 LYS LYS A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 ALA 139 139 139 ALA ALA A . n 
A 1 140 GLY 140 140 140 GLY GLY A . n 
A 1 141 ILE 141 141 141 ILE ILE A . n 
A 1 142 SER 142 142 142 SER SER A . n 
A 1 143 PHE 143 143 143 PHE PHE A . n 
A 1 144 LYS 144 144 144 LYS LYS A . n 
A 1 145 TYR 145 145 145 TYR TYR A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 LYS 148 148 148 LYS LYS A . n 
A 1 149 ASN 149 149 149 ASN ASN A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 ILE 151 151 151 ILE ILE A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 THR 154 154 154 THR THR A . n 
A 1 155 SER 155 155 155 SER SER A . n 
A 1 156 HIS 156 156 156 HIS HIS A . n 
A 1 157 SER 157 157 157 SER SER A . n 
A 1 158 GLY 158 158 158 GLY GLY A . n 
A 1 159 SER 159 159 159 SER SER A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 THR 161 161 161 THR THR A . n 
A 1 162 LEU 162 162 162 LEU LEU A . n 
A 1 163 VAL 163 163 163 VAL VAL A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 ALA 165 165 165 ALA ALA A . n 
A 1 166 PRO 166 166 166 PRO PRO A . n 
B 1 1   GLY 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   LYS 3   3   ?   ?   ?   B . n 
B 1 4   VAL 4   4   ?   ?   ?   B . n 
B 1 5   GLU 5   5   5   GLU GLU B . n 
B 1 6   ALA 6   6   6   ALA ALA B . n 
B 1 7   SER 7   7   7   SER SER B . n 
B 1 8   LYS 8   8   8   LYS LYS B . n 
B 1 9   GLY 9   9   9   GLY GLY B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  GLN 11  11  11  GLN GLN B . n 
B 1 12  VAL 12  12  12  VAL VAL B . n 
B 1 13  THR 13  13  13  THR THR B . n 
B 1 14  ALA 14  14  14  ALA ALA B . n 
B 1 15  SER 15  15  15  SER SER B . n 
B 1 16  GLY 16  16  16  GLY GLY B . n 
B 1 17  VAL 17  17  17  VAL VAL B . n 
B 1 18  SER 18  18  18  SER SER B . n 
B 1 19  VAL 19  19  19  VAL VAL B . n 
B 1 20  GLN 20  20  20  GLN GLN B . n 
B 1 21  ALA 21  21  21  ALA ALA B . n 
B 1 22  GLY 22  22  22  GLY GLY B . n 
B 1 23  ASP 23  23  23  ASP ASP B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  ILE 25  25  25  ILE ILE B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  VAL 27  27  27  VAL VAL B . n 
B 1 28  ALA 28  28  28  ALA ALA B . n 
B 1 29  GLY 29  29  29  GLY GLY B . n 
B 1 30  THR 30  30  30  THR THR B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  VAL 32  32  32  VAL VAL B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  LYS 35  35  35  LYS LYS B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  GLU 37  37  37  GLU GLU B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  SER 39  39  39  SER SER B . n 
B 1 40  LYS 40  40  40  LYS LYS B . n 
B 1 41  GLY 41  41  41  GLY GLY B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  GLN 43  43  43  GLN GLN B . n 
B 1 44  VAL 44  44  44  VAL VAL B . n 
B 1 45  THR 45  45  45  THR THR B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  ASN 47  47  47  ASN ASN B . n 
B 1 48  GLY 48  48  48  GLY GLY B . n 
B 1 49  VAL 49  49  49  VAL VAL B . n 
B 1 50  GLY 50  50  50  GLY GLY B . n 
B 1 51  LEU 51  51  51  LEU LEU B . n 
B 1 52  ASN 52  52  52  ASN ASN B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  THR 54  54  54  THR THR B . n 
B 1 55  ALA 55  55  55  ALA ALA B . n 
B 1 56  TRP 56  56  56  TRP TRP B . n 
B 1 57  ILE 57  57  57  ILE ILE B . n 
B 1 58  LYS 58  58  58  LYS LYS B . n 
B 1 59  MET 59  59  59  MET MET B . n 
B 1 60  MET 60  60  60  MET MET B . n 
B 1 61  CYS 61  61  61  CYS CYS B . n 
B 1 62  GLY 62  62  62  GLY GLY B . n 
B 1 63  LEU 63  63  63  LEU LEU B . n 
B 1 64  HIS 64  64  64  HIS HIS B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  ALA 66  66  66  ALA ALA B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  PHE 68  68  68  PHE PHE B . n 
B 1 69  TYR 69  69  69  TYR TYR B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  SER 71  71  71  SER SER B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  THR 73  73  73  THR THR B . n 
B 1 74  TYR 74  74  74  TYR TYR B . n 
B 1 75  VAL 75  75  75  VAL VAL B . n 
B 1 76  CYS 76  76  76  CYS CYS B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  PHE 78  78  78  PHE PHE B . n 
B 1 79  PHE 79  79  79  PHE PHE B . n 
B 1 80  CYS 80  80  80  CYS CYS B . n 
B 1 81  ASN 81  81  81  ASN ASN B . n 
B 1 82  HIS 82  82  82  HIS HIS B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  THR 84  84  84  THR THR B . n 
B 1 85  GLY 85  85  85  GLY GLY B . n 
B 1 86  CYS 86  86  86  CYS CYS B . n 
B 1 87  THR 87  87  87  THR THR B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  TYR 89  89  89  TYR TYR B . n 
B 1 90  VAL 90  90  90  VAL VAL B . n 
B 1 91  TYR 91  91  91  TYR TYR B . n 
B 1 92  GLY 92  92  92  GLY GLY B . n 
B 1 93  ARG 93  93  93  ARG ARG B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  GLY 95  95  95  GLY GLY B . n 
B 1 96  TYR 96  96  96  TYR TYR B . n 
B 1 97  TYR 97  97  97  TYR TYR B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 MET 100 100 100 MET MET B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 GLY 103 103 103 GLY GLY B . n 
B 1 104 ASP 104 104 104 ASP ASP B . n 
B 1 105 VAL 105 105 105 VAL VAL B . n 
B 1 106 LYS 106 106 106 LYS LYS B . n 
B 1 107 LEU 107 107 107 LEU LEU B . n 
B 1 108 ASN 108 108 108 ASN ASN B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 VAL 110 110 110 VAL VAL B . n 
B 1 111 ASP 111 111 111 ASP ASP B . n 
B 1 112 HIS 112 112 112 HIS HIS B . n 
B 1 113 ASN 113 113 113 ASN ASN B . n 
B 1 114 GLU 114 114 114 GLU GLU B . n 
B 1 115 ILE 115 115 115 ILE ILE B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 SER 117 117 117 SER SER B . n 
B 1 118 MET 118 118 118 MET MET B . n 
B 1 119 VAL 119 119 119 VAL VAL B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 SER 121 121 121 SER SER B . n 
B 1 122 GLY 122 122 122 GLY GLY B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 ILE 124 124 124 ILE ILE B . n 
B 1 125 ALA 125 125 125 ALA ALA B . n 
B 1 126 ALA 126 126 126 ALA ALA B . n 
B 1 127 ALA 127 127 127 ALA ALA B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 MET 129 129 129 MET MET B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 SER 131 131 131 SER SER B . n 
B 1 132 TRP 132 132 132 TRP TRP B . n 
B 1 133 LYS 133 133 133 LYS LYS B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 LYS 136 136 136 LYS LYS B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 ALA 139 139 139 ALA ALA B . n 
B 1 140 GLY 140 140 140 GLY GLY B . n 
B 1 141 ILE 141 141 141 ILE ILE B . n 
B 1 142 SER 142 142 142 SER SER B . n 
B 1 143 PHE 143 143 143 PHE PHE B . n 
B 1 144 LYS 144 144 144 LYS LYS B . n 
B 1 145 TYR 145 145 145 TYR TYR B . n 
B 1 146 LEU 146 146 146 LEU LEU B . n 
B 1 147 GLY 147 147 147 GLY GLY B . n 
B 1 148 LYS 148 148 148 LYS LYS B . n 
B 1 149 ASN 149 149 149 ASN ASN B . n 
B 1 150 LEU 150 150 150 LEU LEU B . n 
B 1 151 ILE 151 151 151 ILE ILE B . n 
B 1 152 THR 152 152 152 THR THR B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 THR 154 154 154 THR THR B . n 
B 1 155 SER 155 155 155 SER SER B . n 
B 1 156 HIS 156 156 156 HIS HIS B . n 
B 1 157 SER 157 157 157 SER SER B . n 
B 1 158 GLY 158 158 158 GLY GLY B . n 
B 1 159 SER 159 159 159 SER SER B . n 
B 1 160 VAL 160 160 160 VAL VAL B . n 
B 1 161 THR 161 161 161 THR THR B . n 
B 1 162 LEU 162 162 162 LEU LEU B . n 
B 1 163 VAL 163 163 163 VAL VAL B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 ALA 165 165 165 ALA ALA B . n 
B 1 166 PRO 166 166 166 PRO PRO B . n 
C 1 1   GLY 1   1   ?   ?   ?   C . n 
C 1 2   ALA 2   2   ?   ?   ?   C . n 
C 1 3   LYS 3   3   ?   ?   ?   C . n 
C 1 4   VAL 4   4   ?   ?   ?   C . n 
C 1 5   GLU 5   5   5   GLU GLU C . n 
C 1 6   ALA 6   6   6   ALA ALA C . n 
C 1 7   SER 7   7   7   SER SER C . n 
C 1 8   LYS 8   8   8   LYS LYS C . n 
C 1 9   GLY 9   9   9   GLY GLY C . n 
C 1 10  LEU 10  10  10  LEU LEU C . n 
C 1 11  GLN 11  11  11  GLN GLN C . n 
C 1 12  VAL 12  12  12  VAL VAL C . n 
C 1 13  THR 13  13  13  THR THR C . n 
C 1 14  ALA 14  14  14  ALA ALA C . n 
C 1 15  SER 15  15  15  SER SER C . n 
C 1 16  GLY 16  16  16  GLY GLY C . n 
C 1 17  VAL 17  17  17  VAL VAL C . n 
C 1 18  SER 18  18  18  SER SER C . n 
C 1 19  VAL 19  19  19  VAL VAL C . n 
C 1 20  GLN 20  20  20  GLN GLN C . n 
C 1 21  ALA 21  21  21  ALA ALA C . n 
C 1 22  GLY 22  22  22  GLY GLY C . n 
C 1 23  ASP 23  23  23  ASP ASP C . n 
C 1 24  GLY 24  24  24  GLY GLY C . n 
C 1 25  ILE 25  25  25  ILE ILE C . n 
C 1 26  SER 26  26  26  SER SER C . n 
C 1 27  VAL 27  27  27  VAL VAL C . n 
C 1 28  ALA 28  28  28  ALA ALA C . n 
C 1 29  GLY 29  29  29  GLY GLY C . n 
C 1 30  THR 30  30  30  THR THR C . n 
C 1 31  GLY 31  31  31  GLY GLY C . n 
C 1 32  VAL 32  32  32  VAL VAL C . n 
C 1 33  ALA 33  33  33  ALA ALA C . n 
C 1 34  VAL 34  34  34  VAL VAL C . n 
C 1 35  LYS 35  35  35  LYS LYS C . n 
C 1 36  VAL 36  36  36  VAL VAL C . n 
C 1 37  GLU 37  37  37  GLU GLU C . n 
C 1 38  ALA 38  38  38  ALA ALA C . n 
C 1 39  SER 39  39  39  SER SER C . n 
C 1 40  LYS 40  40  40  LYS LYS C . n 
C 1 41  GLY 41  41  41  GLY GLY C . n 
C 1 42  LEU 42  42  42  LEU LEU C . n 
C 1 43  GLN 43  43  43  GLN GLN C . n 
C 1 44  VAL 44  44  44  VAL VAL C . n 
C 1 45  THR 45  45  45  THR THR C . n 
C 1 46  SER 46  46  46  SER SER C . n 
C 1 47  ASN 47  47  47  ASN ASN C . n 
C 1 48  GLY 48  48  48  GLY GLY C . n 
C 1 49  VAL 49  49  49  VAL VAL C . n 
C 1 50  GLY 50  50  50  GLY GLY C . n 
C 1 51  LEU 51  51  51  LEU LEU C . n 
C 1 52  ASN 52  52  52  ASN ASN C . n 
C 1 53  ASN 53  53  53  ASN ASN C . n 
C 1 54  THR 54  54  54  THR THR C . n 
C 1 55  ALA 55  55  55  ALA ALA C . n 
C 1 56  TRP 56  56  56  TRP TRP C . n 
C 1 57  ILE 57  57  57  ILE ILE C . n 
C 1 58  LYS 58  58  58  LYS LYS C . n 
C 1 59  MET 59  59  59  MET MET C . n 
C 1 60  MET 60  60  60  MET MET C . n 
C 1 61  CYS 61  61  61  CYS CYS C . n 
C 1 62  GLY 62  62  62  GLY GLY C . n 
C 1 63  LEU 63  63  63  LEU LEU C . n 
C 1 64  HIS 64  64  64  HIS HIS C . n 
C 1 65  ASN 65  65  65  ASN ASN C . n 
C 1 66  ALA 66  66  66  ALA ALA C . n 
C 1 67  THR 67  67  67  THR THR C . n 
C 1 68  PHE 68  68  68  PHE PHE C . n 
C 1 69  TYR 69  69  69  TYR TYR C . n 
C 1 70  VAL 70  70  70  VAL VAL C . n 
C 1 71  SER 71  71  71  SER SER C . n 
C 1 72  ASP 72  72  72  ASP ASP C . n 
C 1 73  THR 73  73  73  THR THR C . n 
C 1 74  TYR 74  74  74  TYR TYR C . n 
C 1 75  VAL 75  75  75  VAL VAL C . n 
C 1 76  CYS 76  76  76  CYS CYS C . n 
C 1 77  VAL 77  77  77  VAL VAL C . n 
C 1 78  PHE 78  78  78  PHE PHE C . n 
C 1 79  PHE 79  79  79  PHE PHE C . n 
C 1 80  CYS 80  80  80  CYS CYS C . n 
C 1 81  ASN 81  81  81  ASN ASN C . n 
C 1 82  HIS 82  82  82  HIS HIS C . n 
C 1 83  SER 83  83  83  SER SER C . n 
C 1 84  THR 84  84  84  THR THR C . n 
C 1 85  GLY 85  85  85  GLY GLY C . n 
C 1 86  CYS 86  86  86  CYS CYS C . n 
C 1 87  THR 87  87  87  THR THR C . n 
C 1 88  ALA 88  88  88  ALA ALA C . n 
C 1 89  TYR 89  89  89  TYR TYR C . n 
C 1 90  VAL 90  90  90  VAL VAL C . n 
C 1 91  TYR 91  91  91  TYR TYR C . n 
C 1 92  GLY 92  92  92  GLY GLY C . n 
C 1 93  ARG 93  93  93  ARG ARG C . n 
C 1 94  GLY 94  94  94  GLY GLY C . n 
C 1 95  GLY 95  95  95  GLY GLY C . n 
C 1 96  TYR 96  96  96  TYR TYR C . n 
C 1 97  TYR 97  97  97  TYR TYR C . n 
C 1 98  LEU 98  98  98  LEU LEU C . n 
C 1 99  SER 99  99  99  SER SER C . n 
C 1 100 MET 100 100 100 MET MET C . n 
C 1 101 TYR 101 101 101 TYR TYR C . n 
C 1 102 LYS 102 102 102 LYS LYS C . n 
C 1 103 GLY 103 103 103 GLY GLY C . n 
C 1 104 ASP 104 104 104 ASP ASP C . n 
C 1 105 VAL 105 105 105 VAL VAL C . n 
C 1 106 LYS 106 106 106 LYS LYS C . n 
C 1 107 LEU 107 107 107 LEU LEU C . n 
C 1 108 ASN 108 108 108 ASN ASN C . n 
C 1 109 SER 109 109 109 SER SER C . n 
C 1 110 VAL 110 110 110 VAL VAL C . n 
C 1 111 ASP 111 111 111 ASP ASP C . n 
C 1 112 HIS 112 112 112 HIS HIS C . n 
C 1 113 ASN 113 113 113 ASN ASN C . n 
C 1 114 GLU 114 114 114 GLU GLU C . n 
C 1 115 ILE 115 115 115 ILE ILE C . n 
C 1 116 ILE 116 116 116 ILE ILE C . n 
C 1 117 SER 117 117 117 SER SER C . n 
C 1 118 MET 118 118 118 MET MET C . n 
C 1 119 VAL 119 119 119 VAL VAL C . n 
C 1 120 GLY 120 120 120 GLY GLY C . n 
C 1 121 SER 121 121 121 SER SER C . n 
C 1 122 GLY 122 122 122 GLY GLY C . n 
C 1 123 SER 123 123 123 SER SER C . n 
C 1 124 ILE 124 124 124 ILE ILE C . n 
C 1 125 ALA 125 125 125 ALA ALA C . n 
C 1 126 ALA 126 126 126 ALA ALA C . n 
C 1 127 ALA 127 127 127 ALA ALA C . n 
C 1 128 THR 128 128 128 THR THR C . n 
C 1 129 MET 129 129 129 MET MET C . n 
C 1 130 VAL 130 130 130 VAL VAL C . n 
C 1 131 SER 131 131 131 SER SER C . n 
C 1 132 TRP 132 132 132 TRP TRP C . n 
C 1 133 LYS 133 133 133 LYS LYS C . n 
C 1 134 SER 134 134 134 SER SER C . n 
C 1 135 THR 135 135 135 THR THR C . n 
C 1 136 LYS 136 136 136 LYS LYS C . n 
C 1 137 ALA 137 137 137 ALA ALA C . n 
C 1 138 ALA 138 138 138 ALA ALA C . n 
C 1 139 ALA 139 139 139 ALA ALA C . n 
C 1 140 GLY 140 140 140 GLY GLY C . n 
C 1 141 ILE 141 141 141 ILE ILE C . n 
C 1 142 SER 142 142 142 SER SER C . n 
C 1 143 PHE 143 143 143 PHE PHE C . n 
C 1 144 LYS 144 144 144 LYS LYS C . n 
C 1 145 TYR 145 145 145 TYR TYR C . n 
C 1 146 LEU 146 146 146 LEU LEU C . n 
C 1 147 GLY 147 147 147 GLY GLY C . n 
C 1 148 LYS 148 148 148 LYS LYS C . n 
C 1 149 ASN 149 149 149 ASN ASN C . n 
C 1 150 LEU 150 150 150 LEU LEU C . n 
C 1 151 ILE 151 151 151 ILE ILE C . n 
C 1 152 THR 152 152 152 THR THR C . n 
C 1 153 SER 153 153 153 SER SER C . n 
C 1 154 THR 154 154 154 THR THR C . n 
C 1 155 SER 155 155 155 SER SER C . n 
C 1 156 HIS 156 156 156 HIS HIS C . n 
C 1 157 SER 157 157 157 SER SER C . n 
C 1 158 GLY 158 158 158 GLY GLY C . n 
C 1 159 SER 159 159 159 SER SER C . n 
C 1 160 VAL 160 160 160 VAL VAL C . n 
C 1 161 THR 161 161 161 THR THR C . n 
C 1 162 LEU 162 162 162 LEU LEU C . n 
C 1 163 VAL 163 163 163 VAL VAL C . n 
C 1 164 ALA 164 164 164 ALA ALA C . n 
C 1 165 ALA 165 165 165 ALA ALA C . n 
C 1 166 PRO 166 166 166 PRO PRO C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 2 NH4 1   201 1   NH4 NH4 A . 
E 3 GOL 1   202 1   GOL GOL A . 
F 4 CIT 1   201 1   CIT CIT B . 
G 3 GOL 1   202 2   GOL GOL B . 
H 3 GOL 1   201 3   GOL GOL C . 
I 5 HOH 1   301 261 HOH HOH A . 
I 5 HOH 2   302 70  HOH HOH A . 
I 5 HOH 3   303 265 HOH HOH A . 
I 5 HOH 4   304 66  HOH HOH A . 
I 5 HOH 5   305 98  HOH HOH A . 
I 5 HOH 6   306 153 HOH HOH A . 
I 5 HOH 7   307 67  HOH HOH A . 
I 5 HOH 8   308 260 HOH HOH A . 
I 5 HOH 9   309 75  HOH HOH A . 
I 5 HOH 10  310 242 HOH HOH A . 
I 5 HOH 11  311 138 HOH HOH A . 
I 5 HOH 12  312 235 HOH HOH A . 
I 5 HOH 13  313 191 HOH HOH A . 
I 5 HOH 14  314 173 HOH HOH A . 
I 5 HOH 15  315 202 HOH HOH A . 
I 5 HOH 16  316 35  HOH HOH A . 
I 5 HOH 17  317 118 HOH HOH A . 
I 5 HOH 18  318 183 HOH HOH A . 
I 5 HOH 19  319 96  HOH HOH A . 
I 5 HOH 20  320 228 HOH HOH A . 
I 5 HOH 21  321 83  HOH HOH A . 
I 5 HOH 22  322 113 HOH HOH A . 
I 5 HOH 23  323 106 HOH HOH A . 
I 5 HOH 24  324 14  HOH HOH A . 
I 5 HOH 25  325 123 HOH HOH A . 
I 5 HOH 26  326 1   HOH HOH A . 
I 5 HOH 27  327 33  HOH HOH A . 
I 5 HOH 28  328 2   HOH HOH A . 
I 5 HOH 29  329 7   HOH HOH A . 
I 5 HOH 30  330 100 HOH HOH A . 
I 5 HOH 31  331 109 HOH HOH A . 
I 5 HOH 32  332 86  HOH HOH A . 
I 5 HOH 33  333 116 HOH HOH A . 
I 5 HOH 34  334 243 HOH HOH A . 
I 5 HOH 35  335 117 HOH HOH A . 
I 5 HOH 36  336 28  HOH HOH A . 
I 5 HOH 37  337 12  HOH HOH A . 
I 5 HOH 38  338 3   HOH HOH A . 
I 5 HOH 39  339 194 HOH HOH A . 
I 5 HOH 40  340 39  HOH HOH A . 
I 5 HOH 41  341 214 HOH HOH A . 
I 5 HOH 42  342 135 HOH HOH A . 
I 5 HOH 43  343 104 HOH HOH A . 
I 5 HOH 44  344 190 HOH HOH A . 
I 5 HOH 45  345 77  HOH HOH A . 
I 5 HOH 46  346 238 HOH HOH A . 
I 5 HOH 47  347 114 HOH HOH A . 
I 5 HOH 48  348 232 HOH HOH A . 
I 5 HOH 49  349 227 HOH HOH A . 
I 5 HOH 50  350 185 HOH HOH A . 
I 5 HOH 51  351 158 HOH HOH A . 
I 5 HOH 52  352 56  HOH HOH A . 
I 5 HOH 53  353 142 HOH HOH A . 
I 5 HOH 54  354 244 HOH HOH A . 
I 5 HOH 55  355 49  HOH HOH A . 
I 5 HOH 56  356 145 HOH HOH A . 
I 5 HOH 57  357 25  HOH HOH A . 
I 5 HOH 58  358 89  HOH HOH A . 
I 5 HOH 59  359 53  HOH HOH A . 
I 5 HOH 60  360 15  HOH HOH A . 
I 5 HOH 61  361 251 HOH HOH A . 
I 5 HOH 62  362 6   HOH HOH A . 
I 5 HOH 63  363 156 HOH HOH A . 
I 5 HOH 64  364 112 HOH HOH A . 
I 5 HOH 65  365 241 HOH HOH A . 
I 5 HOH 66  366 44  HOH HOH A . 
I 5 HOH 67  367 51  HOH HOH A . 
I 5 HOH 68  368 63  HOH HOH A . 
I 5 HOH 69  369 262 HOH HOH A . 
I 5 HOH 70  370 64  HOH HOH A . 
I 5 HOH 71  371 34  HOH HOH A . 
I 5 HOH 72  372 203 HOH HOH A . 
I 5 HOH 73  373 125 HOH HOH A . 
I 5 HOH 74  374 215 HOH HOH A . 
I 5 HOH 75  375 139 HOH HOH A . 
I 5 HOH 76  376 29  HOH HOH A . 
I 5 HOH 77  377 271 HOH HOH A . 
I 5 HOH 78  378 149 HOH HOH A . 
I 5 HOH 79  379 73  HOH HOH A . 
I 5 HOH 80  380 81  HOH HOH A . 
I 5 HOH 81  381 21  HOH HOH A . 
I 5 HOH 82  382 268 HOH HOH A . 
I 5 HOH 83  383 245 HOH HOH A . 
I 5 HOH 84  384 256 HOH HOH A . 
I 5 HOH 85  385 140 HOH HOH A . 
I 5 HOH 86  386 48  HOH HOH A . 
I 5 HOH 87  387 223 HOH HOH A . 
I 5 HOH 88  388 237 HOH HOH A . 
I 5 HOH 89  389 254 HOH HOH A . 
I 5 HOH 90  390 240 HOH HOH A . 
I 5 HOH 91  391 207 HOH HOH A . 
I 5 HOH 92  392 200 HOH HOH A . 
I 5 HOH 93  393 272 HOH HOH A . 
I 5 HOH 94  394 263 HOH HOH A . 
I 5 HOH 95  395 134 HOH HOH A . 
I 5 HOH 96  396 230 HOH HOH A . 
I 5 HOH 97  397 95  HOH HOH A . 
I 5 HOH 98  398 37  HOH HOH A . 
I 5 HOH 99  399 209 HOH HOH A . 
I 5 HOH 100 400 108 HOH HOH A . 
I 5 HOH 101 401 231 HOH HOH A . 
J 5 HOH 1   301 267 HOH HOH B . 
J 5 HOH 2   302 102 HOH HOH B . 
J 5 HOH 3   303 220 HOH HOH B . 
J 5 HOH 4   304 193 HOH HOH B . 
J 5 HOH 5   305 252 HOH HOH B . 
J 5 HOH 6   306 154 HOH HOH B . 
J 5 HOH 7   307 221 HOH HOH B . 
J 5 HOH 8   308 155 HOH HOH B . 
J 5 HOH 9   309 94  HOH HOH B . 
J 5 HOH 10  310 84  HOH HOH B . 
J 5 HOH 11  311 26  HOH HOH B . 
J 5 HOH 12  312 205 HOH HOH B . 
J 5 HOH 13  313 257 HOH HOH B . 
J 5 HOH 14  314 168 HOH HOH B . 
J 5 HOH 15  315 90  HOH HOH B . 
J 5 HOH 16  316 9   HOH HOH B . 
J 5 HOH 17  317 38  HOH HOH B . 
J 5 HOH 18  318 253 HOH HOH B . 
J 5 HOH 19  319 201 HOH HOH B . 
J 5 HOH 20  320 78  HOH HOH B . 
J 5 HOH 21  321 45  HOH HOH B . 
J 5 HOH 22  322 143 HOH HOH B . 
J 5 HOH 23  323 27  HOH HOH B . 
J 5 HOH 24  324 166 HOH HOH B . 
J 5 HOH 25  325 131 HOH HOH B . 
J 5 HOH 26  326 181 HOH HOH B . 
J 5 HOH 27  327 211 HOH HOH B . 
J 5 HOH 28  328 151 HOH HOH B . 
J 5 HOH 29  329 79  HOH HOH B . 
J 5 HOH 30  330 88  HOH HOH B . 
J 5 HOH 31  331 264 HOH HOH B . 
J 5 HOH 32  332 222 HOH HOH B . 
J 5 HOH 33  333 239 HOH HOH B . 
J 5 HOH 34  334 137 HOH HOH B . 
J 5 HOH 35  335 120 HOH HOH B . 
J 5 HOH 36  336 5   HOH HOH B . 
J 5 HOH 37  337 22  HOH HOH B . 
J 5 HOH 38  338 61  HOH HOH B . 
J 5 HOH 39  339 60  HOH HOH B . 
J 5 HOH 40  340 178 HOH HOH B . 
J 5 HOH 41  341 162 HOH HOH B . 
J 5 HOH 42  342 128 HOH HOH B . 
J 5 HOH 43  343 18  HOH HOH B . 
J 5 HOH 44  344 74  HOH HOH B . 
J 5 HOH 45  345 165 HOH HOH B . 
J 5 HOH 46  346 10  HOH HOH B . 
J 5 HOH 47  347 17  HOH HOH B . 
J 5 HOH 48  348 234 HOH HOH B . 
J 5 HOH 49  349 65  HOH HOH B . 
J 5 HOH 50  350 68  HOH HOH B . 
J 5 HOH 51  351 110 HOH HOH B . 
J 5 HOH 52  352 147 HOH HOH B . 
J 5 HOH 53  353 233 HOH HOH B . 
J 5 HOH 54  354 92  HOH HOH B . 
J 5 HOH 55  355 199 HOH HOH B . 
J 5 HOH 56  356 71  HOH HOH B . 
J 5 HOH 57  357 167 HOH HOH B . 
J 5 HOH 58  358 115 HOH HOH B . 
J 5 HOH 59  359 157 HOH HOH B . 
J 5 HOH 60  360 170 HOH HOH B . 
J 5 HOH 61  361 99  HOH HOH B . 
J 5 HOH 62  362 52  HOH HOH B . 
J 5 HOH 63  363 136 HOH HOH B . 
J 5 HOH 64  364 188 HOH HOH B . 
J 5 HOH 65  365 249 HOH HOH B . 
J 5 HOH 66  366 129 HOH HOH B . 
J 5 HOH 67  367 184 HOH HOH B . 
J 5 HOH 68  368 121 HOH HOH B . 
J 5 HOH 69  369 163 HOH HOH B . 
J 5 HOH 70  370 43  HOH HOH B . 
J 5 HOH 71  371 58  HOH HOH B . 
J 5 HOH 72  372 126 HOH HOH B . 
J 5 HOH 73  373 144 HOH HOH B . 
J 5 HOH 74  374 119 HOH HOH B . 
J 5 HOH 75  375 204 HOH HOH B . 
J 5 HOH 76  376 177 HOH HOH B . 
J 5 HOH 77  377 69  HOH HOH B . 
J 5 HOH 78  378 72  HOH HOH B . 
J 5 HOH 79  379 212 HOH HOH B . 
J 5 HOH 80  380 171 HOH HOH B . 
J 5 HOH 81  381 175 HOH HOH B . 
J 5 HOH 82  382 246 HOH HOH B . 
J 5 HOH 83  383 41  HOH HOH B . 
J 5 HOH 84  384 258 HOH HOH B . 
J 5 HOH 85  385 255 HOH HOH B . 
J 5 HOH 86  386 266 HOH HOH B . 
J 5 HOH 87  387 132 HOH HOH B . 
J 5 HOH 88  388 236 HOH HOH B . 
J 5 HOH 89  389 197 HOH HOH B . 
J 5 HOH 90  390 273 HOH HOH B . 
J 5 HOH 91  391 198 HOH HOH B . 
J 5 HOH 92  392 160 HOH HOH B . 
J 5 HOH 93  393 169 HOH HOH B . 
K 5 HOH 1   301 152 HOH HOH C . 
K 5 HOH 2   302 269 HOH HOH C . 
K 5 HOH 3   303 148 HOH HOH C . 
K 5 HOH 4   304 186 HOH HOH C . 
K 5 HOH 5   305 192 HOH HOH C . 
K 5 HOH 6   306 103 HOH HOH C . 
K 5 HOH 7   307 46  HOH HOH C . 
K 5 HOH 8   308 133 HOH HOH C . 
K 5 HOH 9   309 218 HOH HOH C . 
K 5 HOH 10  310 174 HOH HOH C . 
K 5 HOH 11  311 216 HOH HOH C . 
K 5 HOH 12  312 161 HOH HOH C . 
K 5 HOH 13  313 196 HOH HOH C . 
K 5 HOH 14  314 130 HOH HOH C . 
K 5 HOH 15  315 187 HOH HOH C . 
K 5 HOH 16  316 176 HOH HOH C . 
K 5 HOH 17  317 55  HOH HOH C . 
K 5 HOH 18  318 97  HOH HOH C . 
K 5 HOH 19  319 24  HOH HOH C . 
K 5 HOH 20  320 76  HOH HOH C . 
K 5 HOH 21  321 229 HOH HOH C . 
K 5 HOH 22  322 206 HOH HOH C . 
K 5 HOH 23  323 172 HOH HOH C . 
K 5 HOH 24  324 225 HOH HOH C . 
K 5 HOH 25  325 146 HOH HOH C . 
K 5 HOH 26  326 213 HOH HOH C . 
K 5 HOH 27  327 259 HOH HOH C . 
K 5 HOH 28  328 179 HOH HOH C . 
K 5 HOH 29  329 16  HOH HOH C . 
K 5 HOH 30  330 85  HOH HOH C . 
K 5 HOH 31  331 82  HOH HOH C . 
K 5 HOH 32  332 54  HOH HOH C . 
K 5 HOH 33  333 189 HOH HOH C . 
K 5 HOH 34  334 111 HOH HOH C . 
K 5 HOH 35  335 31  HOH HOH C . 
K 5 HOH 36  336 13  HOH HOH C . 
K 5 HOH 37  337 40  HOH HOH C . 
K 5 HOH 38  338 80  HOH HOH C . 
K 5 HOH 39  339 250 HOH HOH C . 
K 5 HOH 40  340 101 HOH HOH C . 
K 5 HOH 41  341 4   HOH HOH C . 
K 5 HOH 42  342 19  HOH HOH C . 
K 5 HOH 43  343 210 HOH HOH C . 
K 5 HOH 44  344 30  HOH HOH C . 
K 5 HOH 45  345 47  HOH HOH C . 
K 5 HOH 46  346 57  HOH HOH C . 
K 5 HOH 47  347 180 HOH HOH C . 
K 5 HOH 48  348 195 HOH HOH C . 
K 5 HOH 49  349 105 HOH HOH C . 
K 5 HOH 50  350 62  HOH HOH C . 
K 5 HOH 51  351 59  HOH HOH C . 
K 5 HOH 52  352 23  HOH HOH C . 
K 5 HOH 53  353 42  HOH HOH C . 
K 5 HOH 54  354 11  HOH HOH C . 
K 5 HOH 55  355 226 HOH HOH C . 
K 5 HOH 56  356 247 HOH HOH C . 
K 5 HOH 57  357 122 HOH HOH C . 
K 5 HOH 58  358 217 HOH HOH C . 
K 5 HOH 59  359 248 HOH HOH C . 
K 5 HOH 60  360 270 HOH HOH C . 
K 5 HOH 61  361 87  HOH HOH C . 
K 5 HOH 62  362 208 HOH HOH C . 
K 5 HOH 63  363 93  HOH HOH C . 
K 5 HOH 64  364 164 HOH HOH C . 
K 5 HOH 65  365 219 HOH HOH C . 
K 5 HOH 66  366 50  HOH HOH C . 
K 5 HOH 67  367 182 HOH HOH C . 
K 5 HOH 68  368 150 HOH HOH C . 
K 5 HOH 69  369 107 HOH HOH C . 
K 5 HOH 70  370 124 HOH HOH C . 
K 5 HOH 71  371 20  HOH HOH C . 
K 5 HOH 72  372 32  HOH HOH C . 
K 5 HOH 73  373 36  HOH HOH C . 
K 5 HOH 74  374 8   HOH HOH C . 
K 5 HOH 75  375 127 HOH HOH C . 
K 5 HOH 76  376 224 HOH HOH C . 
K 5 HOH 77  377 159 HOH HOH C . 
K 5 HOH 78  378 274 HOH HOH C . 
K 5 HOH 79  379 141 HOH HOH C . 
K 5 HOH 80  380 91  HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A LYS 3   ? CG  ? A LYS 3   CG  
2  1 Y 1 A LYS 3   ? CD  ? A LYS 3   CD  
3  1 Y 1 A LYS 3   ? CE  ? A LYS 3   CE  
4  1 Y 1 A LYS 3   ? NZ  ? A LYS 3   NZ  
5  1 Y 1 A TYR 101 ? CG  ? A TYR 101 CG  
6  1 Y 1 A TYR 101 ? CD1 ? A TYR 101 CD1 
7  1 Y 1 A TYR 101 ? CD2 ? A TYR 101 CD2 
8  1 Y 1 A TYR 101 ? CE1 ? A TYR 101 CE1 
9  1 Y 1 A TYR 101 ? CE2 ? A TYR 101 CE2 
10 1 Y 1 A TYR 101 ? CZ  ? A TYR 101 CZ  
11 1 Y 1 A TYR 101 ? OH  ? A TYR 101 OH  
12 1 Y 1 A LYS 102 ? CG  ? A LYS 102 CG  
13 1 Y 1 A LYS 102 ? CD  ? A LYS 102 CD  
14 1 Y 1 A LYS 102 ? CE  ? A LYS 102 CE  
15 1 Y 1 A LYS 102 ? NZ  ? A LYS 102 NZ  
16 1 Y 1 A LYS 144 ? CG  ? A LYS 144 CG  
17 1 Y 1 A LYS 144 ? CD  ? A LYS 144 CD  
18 1 Y 1 A LYS 144 ? CE  ? A LYS 144 CE  
19 1 Y 1 A LYS 144 ? NZ  ? A LYS 144 NZ  
20 1 Y 1 B GLU 5   ? CG  ? B GLU 5   CG  
21 1 Y 1 B GLU 5   ? CD  ? B GLU 5   CD  
22 1 Y 1 B GLU 5   ? OE1 ? B GLU 5   OE1 
23 1 Y 1 B GLU 5   ? OE2 ? B GLU 5   OE2 
24 1 Y 1 B TYR 74  ? CG  ? B TYR 74  CG  
25 1 Y 1 B TYR 74  ? CD1 ? B TYR 74  CD1 
26 1 Y 1 B TYR 74  ? CD2 ? B TYR 74  CD2 
27 1 Y 1 B TYR 74  ? CE1 ? B TYR 74  CE1 
28 1 Y 1 B TYR 74  ? CE2 ? B TYR 74  CE2 
29 1 Y 1 B TYR 74  ? CZ  ? B TYR 74  CZ  
30 1 Y 1 B TYR 74  ? OH  ? B TYR 74  OH  
31 1 Y 1 B LYS 102 ? CG  ? B LYS 102 CG  
32 1 Y 1 B LYS 102 ? CD  ? B LYS 102 CD  
33 1 Y 1 B LYS 102 ? CE  ? B LYS 102 CE  
34 1 Y 1 B LYS 102 ? NZ  ? B LYS 102 NZ  
35 1 Y 1 C TYR 101 ? CG  ? C TYR 101 CG  
36 1 Y 1 C TYR 101 ? CD1 ? C TYR 101 CD1 
37 1 Y 1 C TYR 101 ? CD2 ? C TYR 101 CD2 
38 1 Y 1 C TYR 101 ? CE1 ? C TYR 101 CE1 
39 1 Y 1 C TYR 101 ? CE2 ? C TYR 101 CE2 
40 1 Y 1 C TYR 101 ? CZ  ? C TYR 101 CZ  
41 1 Y 1 C TYR 101 ? OH  ? C TYR 101 OH  
42 1 Y 1 C LYS 102 ? CG  ? C LYS 102 CG  
43 1 Y 1 C LYS 102 ? CD  ? C LYS 102 CD  
44 1 Y 1 C LYS 102 ? CE  ? C LYS 102 CE  
45 1 Y 1 C LYS 102 ? NZ  ? C LYS 102 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.18.2_3874 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UUS 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     59.113 
_cell.length_a_esd                 ? 
_cell.length_b                     68.241 
_cell.length_b_esd                 ? 
_cell.length_c                     111.290 
_cell.length_c_esd                 ? 
_cell.volume                       448936.096 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UUS 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            'P 2 2ab (z,x,y)' 
_symmetry.space_group_name_H-M             'P 2 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UUS 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.19 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          43.94 
_exptl_crystal.description                  Rod 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;16% PEG 3350,
0.15 M Ammonium citrate
;
_exptl_crystal_grow.pdbx_pH_range   '4.5 - 4.9' 
_exptl_crystal_grow.temp            291 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CCD 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'ADSC QUANTUM 210r' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2020-03-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.953725 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'AUSTRALIAN SYNCHROTRON BEAMLINE MX1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.953725 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   MX1 
_diffrn_source.pdbx_synchrotron_site       'Australian Synchrotron' 
# 
_reflns.B_iso_Wilson_estimate                          16.91 
_reflns.entry_id                                       8UUS 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.47 
_reflns.d_resolution_low                               44.6 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     77498 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.9 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          10 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.061 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.47 
_reflns_shell.d_res_low                                     1.49 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.8 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3684 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               13.4 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               1.112 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.521 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          97.1 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               19.31 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UUS 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.47 
_refine.ls_d_res_low                             32.62 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     77379 
_refine.ls_number_reflns_R_free                  3886 
_refine.ls_number_reflns_R_work                  73493 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.84 
_refine.ls_percent_reflns_R_free                 5.02 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1946 
_refine.ls_R_factor_R_free                       0.2244 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1931 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.33 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 22.4094 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1673 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.47 
_refine_hist.d_res_low                        32.62 
_refine_hist.number_atoms_solvent             274 
_refine_hist.number_atoms_total               3765 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3459 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         32 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0057 ? 3542 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9120 ? 4801 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0924 ? 571  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0046 ? 597  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 9.8595 ? 519  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.47 1.49 . . 152 2485 96.17  . . . . 0.3244 . . . . . . . . . . . 0.3470 
'X-RAY DIFFRACTION' 1.49 1.51 . . 152 2594 99.89  . . . . 0.2891 . . . . . . . . . . . 0.3125 
'X-RAY DIFFRACTION' 1.51 1.53 . . 128 2570 99.82  . . . . 0.2773 . . . . . . . . . . . 0.2930 
'X-RAY DIFFRACTION' 1.53 1.55 . . 139 2595 99.93  . . . . 0.2551 . . . . . . . . . . . 0.2546 
'X-RAY DIFFRACTION' 1.55 1.57 . . 137 2590 99.93  . . . . 0.2391 . . . . . . . . . . . 0.2696 
'X-RAY DIFFRACTION' 1.57 1.59 . . 135 2641 100.00 . . . . 0.2433 . . . . . . . . . . . 0.2728 
'X-RAY DIFFRACTION' 1.59 1.62 . . 130 2583 99.93  . . . . 0.2419 . . . . . . . . . . . 0.2878 
'X-RAY DIFFRACTION' 1.62 1.64 . . 143 2608 100.00 . . . . 0.2326 . . . . . . . . . . . 0.2937 
'X-RAY DIFFRACTION' 1.64 1.67 . . 154 2575 99.96  . . . . 0.2233 . . . . . . . . . . . 0.2567 
'X-RAY DIFFRACTION' 1.67 1.70 . . 140 2590 99.93  . . . . 0.2282 . . . . . . . . . . . 0.2768 
'X-RAY DIFFRACTION' 1.70 1.73 . . 114 2622 100.00 . . . . 0.2215 . . . . . . . . . . . 0.2498 
'X-RAY DIFFRACTION' 1.73 1.77 . . 123 2621 100.00 . . . . 0.2205 . . . . . . . . . . . 0.2652 
'X-RAY DIFFRACTION' 1.77 1.81 . . 127 2619 100.00 . . . . 0.2234 . . . . . . . . . . . 0.2650 
'X-RAY DIFFRACTION' 1.81 1.85 . . 133 2633 100.00 . . . . 0.2027 . . . . . . . . . . . 0.2494 
'X-RAY DIFFRACTION' 1.85 1.90 . . 129 2601 100.00 . . . . 0.1855 . . . . . . . . . . . 0.2001 
'X-RAY DIFFRACTION' 1.90 1.95 . . 105 2646 100.00 . . . . 0.1867 . . . . . . . . . . . 0.2248 
'X-RAY DIFFRACTION' 1.95 2.01 . . 163 2605 100.00 . . . . 0.1830 . . . . . . . . . . . 0.2276 
'X-RAY DIFFRACTION' 2.01 2.07 . . 149 2595 100.00 . . . . 0.1759 . . . . . . . . . . . 0.1936 
'X-RAY DIFFRACTION' 2.07 2.14 . . 128 2638 100.00 . . . . 0.1862 . . . . . . . . . . . 0.2243 
'X-RAY DIFFRACTION' 2.14 2.23 . . 154 2603 99.96  . . . . 0.1795 . . . . . . . . . . . 0.2243 
'X-RAY DIFFRACTION' 2.23 2.33 . . 109 2670 100.00 . . . . 0.1859 . . . . . . . . . . . 0.2508 
'X-RAY DIFFRACTION' 2.33 2.45 . . 146 2636 100.00 . . . . 0.1964 . . . . . . . . . . . 0.2269 
'X-RAY DIFFRACTION' 2.45 2.61 . . 138 2641 100.00 . . . . 0.1967 . . . . . . . . . . . 0.2125 
'X-RAY DIFFRACTION' 2.61 2.81 . . 152 2662 100.00 . . . . 0.1967 . . . . . . . . . . . 0.2258 
'X-RAY DIFFRACTION' 2.81 3.09 . . 147 2643 100.00 . . . . 0.1932 . . . . . . . . . . . 0.2023 
'X-RAY DIFFRACTION' 3.09 3.54 . . 158 2671 100.00 . . . . 0.1751 . . . . . . . . . . . 0.1939 
'X-RAY DIFFRACTION' 3.54 4.46 . . 149 2708 100.00 . . . . 0.1609 . . . . . . . . . . . 0.2045 
'X-RAY DIFFRACTION' 4.46 10.0 . . 152 2848 99.93  . . . . 0.1829 . . . . . . . . . . . 0.2127 
# 
_struct.entry_id                     8UUS 
_struct.title                        'Structure of Serratia proteamaculans antifeeding prophage Fibre foot domain (AfpX13)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UUS 
_struct_keywords.text            'Anti-feeding prophage, Fibre foot, Cell binding, STRUCTURAL PROTEIN' 
_struct_keywords.pdbx_keywords   'STRUCTURAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 4 ? 
G N N 3 ? 
H N N 3 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A2R2Q2I2_SERPR 
_struct_ref.pdbx_db_accession          A0A2R2Q2I2 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;KVEASKGLQVTASGVSVQAGDGISVAGTGVAVKVEASKGLQVTSNGVGLNNTAWIKMMCGLHNATFYVSDTYVCVFFCNH
STGCTAYVYGRGGYYLSMYKGDVKLNSVDHNEIISMVGSGSIAAATMVSWKSTKAAAGISFKYLGKNLITSTSHSGSVTL
VAAP
;
_struct_ref.pdbx_align_begin           427 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UUS A 3 ? 166 ? A0A2R2Q2I2 427 ? 590 ? 3 166 
2 1 8UUS B 3 ? 166 ? A0A2R2Q2I2 427 ? 590 ? 3 166 
3 1 8UUS C 3 ? 166 ? A0A2R2Q2I2 427 ? 590 ? 3 166 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UUS GLY A 1 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 1 1 
1 8UUS ALA A 2 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 2 2 
2 8UUS GLY B 1 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 1 3 
2 8UUS ALA B 2 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 2 4 
3 8UUS GLY C 1 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 1 5 
3 8UUS ALA C 2 ? UNP A0A2R2Q2I2 ? ? 'expression tag' 2 6 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 12520 ? 
1 MORE         -93   ? 
1 'SSA (A^2)'  17760 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLU A 37 ? LYS A 40 ? GLU A 37 LYS A 40 5 ? 4  
HELX_P HELX_P2 AA2 THR A 54 ? ASN A 65 ? THR A 54 ASN A 65 1 ? 12 
HELX_P HELX_P3 AA3 THR B 54 ? ASN B 65 ? THR B 54 ASN B 65 1 ? 12 
HELX_P HELX_P4 AA4 GLU C 37 ? LYS C 40 ? GLU C 37 LYS C 40 5 ? 4  
HELX_P HELX_P5 AA5 THR C 54 ? ASN C 65 ? THR C 54 ASN C 65 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 2 ? 
AA3 ? 2 ? 
AA4 ? 6 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 2 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 3 ? 
AB4 ? 2 ? 
AB5 ? 2 ? 
AB6 ? 2 ? 
AB7 ? 6 ? 
AB8 ? 4 ? 
AB9 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB7 4 5 ? anti-parallel 
AB7 5 6 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 10  ? THR A 13  ? LEU A 10  THR A 13  
AA1 2 GLY A 16  ? VAL A 19  ? GLY A 16  VAL A 19  
AA2 1 ILE A 25  ? ALA A 28  ? ILE A 25  ALA A 28  
AA2 2 GLY A 31  ? VAL A 34  ? GLY A 31  VAL A 34  
AA3 1 LEU A 42  ? THR A 45  ? LEU A 42  THR A 45  
AA3 2 GLY A 48  ? LEU A 51  ? GLY A 48  LEU A 51  
AA4 1 GLU A 114 ? MET A 118 ? GLU A 114 MET A 118 
AA4 2 ALA A 126 ? TRP A 132 ? ALA A 126 TRP A 132 
AA4 3 GLY A 85  ? GLY A 92  ? GLY A 85  GLY A 92  
AA4 4 VAL A 75  ? HIS A 82  ? VAL A 75  HIS A 82  
AA4 5 PHE A 68  ? SER A 71  ? PHE A 68  SER A 71  
AA4 6 VAL A 163 ? ALA A 164 ? VAL A 163 ALA A 164 
AA5 1 TYR A 96  ? LEU A 98  ? TYR A 96  LEU A 98  
AA5 2 SER A 142 ? ASN A 149 ? SER A 142 ASN A 149 
AA5 3 VAL A 105 ? LEU A 107 ? VAL A 105 LEU A 107 
AA5 4 VAL A 110 ? ASP A 111 ? VAL A 110 ASP A 111 
AA6 1 TYR A 96  ? LEU A 98  ? TYR A 96  LEU A 98  
AA6 2 SER A 142 ? ASN A 149 ? SER A 142 ASN A 149 
AA6 3 HIS A 156 ? THR A 161 ? HIS A 156 THR A 161 
AA7 1 LEU B 10  ? THR B 13  ? LEU B 10  THR B 13  
AA7 2 GLY B 16  ? VAL B 19  ? GLY B 16  VAL B 19  
AA8 1 ILE B 25  ? ALA B 28  ? ILE B 25  ALA B 28  
AA8 2 GLY B 31  ? VAL B 34  ? GLY B 31  VAL B 34  
AA9 1 LEU B 42  ? THR B 45  ? LEU B 42  THR B 45  
AA9 2 GLY B 48  ? LEU B 51  ? GLY B 48  LEU B 51  
AB1 1 ILE B 115 ? VAL B 119 ? ILE B 115 VAL B 119 
AB1 2 ALA B 125 ? TRP B 132 ? ALA B 125 TRP B 132 
AB1 3 GLY B 85  ? GLY B 92  ? GLY B 85  GLY B 92  
AB1 4 VAL B 75  ? HIS B 82  ? VAL B 75  HIS B 82  
AB1 5 PHE B 68  ? SER B 71  ? PHE B 68  SER B 71  
AB1 6 VAL B 163 ? ALA B 164 ? VAL B 163 ALA B 164 
AB2 1 TYR B 97  ? LEU B 98  ? TYR B 97  LEU B 98  
AB2 2 SER B 142 ? LYS B 148 ? SER B 142 LYS B 148 
AB2 3 VAL B 105 ? LEU B 107 ? VAL B 105 LEU B 107 
AB2 4 VAL B 110 ? ASP B 111 ? VAL B 110 ASP B 111 
AB3 1 TYR B 97  ? LEU B 98  ? TYR B 97  LEU B 98  
AB3 2 SER B 142 ? LYS B 148 ? SER B 142 LYS B 148 
AB3 3 HIS B 156 ? THR B 161 ? HIS B 156 THR B 161 
AB4 1 LEU C 10  ? THR C 13  ? LEU C 10  THR C 13  
AB4 2 GLY C 16  ? VAL C 19  ? GLY C 16  VAL C 19  
AB5 1 ILE C 25  ? ALA C 28  ? ILE C 25  ALA C 28  
AB5 2 GLY C 31  ? VAL C 34  ? GLY C 31  VAL C 34  
AB6 1 LEU C 42  ? THR C 45  ? LEU C 42  THR C 45  
AB6 2 GLY C 48  ? LEU C 51  ? GLY C 48  LEU C 51  
AB7 1 GLU C 114 ? VAL C 119 ? GLU C 114 VAL C 119 
AB7 2 ALA C 125 ? TRP C 132 ? ALA C 125 TRP C 132 
AB7 3 GLY C 85  ? GLY C 92  ? GLY C 85  GLY C 92  
AB7 4 VAL C 75  ? HIS C 82  ? VAL C 75  HIS C 82  
AB7 5 PHE C 68  ? SER C 71  ? PHE C 68  SER C 71  
AB7 6 VAL C 163 ? ALA C 164 ? VAL C 163 ALA C 164 
AB8 1 TYR C 97  ? LEU C 98  ? TYR C 97  LEU C 98  
AB8 2 SER C 142 ? LYS C 148 ? SER C 142 LYS C 148 
AB8 3 VAL C 105 ? LEU C 107 ? VAL C 105 LEU C 107 
AB8 4 VAL C 110 ? ASP C 111 ? VAL C 110 ASP C 111 
AB9 1 TYR C 97  ? LEU C 98  ? TYR C 97  LEU C 98  
AB9 2 SER C 142 ? LYS C 148 ? SER C 142 LYS C 148 
AB9 3 HIS C 156 ? THR C 161 ? HIS C 156 THR C 161 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 13  ? N THR A 13  O GLY A 16  ? O GLY A 16  
AA2 1 2 N SER A 26  ? N SER A 26  O ALA A 33  ? O ALA A 33  
AA3 1 2 N GLN A 43  ? N GLN A 43  O GLY A 50  ? O GLY A 50  
AA4 1 2 N ILE A 116 ? N ILE A 116 O THR A 128 ? O THR A 128 
AA4 2 3 O VAL A 130 ? O VAL A 130 N ALA A 88  ? N ALA A 88  
AA4 3 4 O TYR A 91  ? O TYR A 91  N CYS A 76  ? N CYS A 76  
AA4 4 5 O PHE A 79  ? O PHE A 79  N PHE A 68  ? N PHE A 68  
AA4 5 6 N TYR A 69  ? N TYR A 69  O VAL A 163 ? O VAL A 163 
AA5 1 2 N TYR A 97  ? N TYR A 97  O LYS A 148 ? O LYS A 148 
AA5 2 3 O LYS A 144 ? O LYS A 144 N LYS A 106 ? N LYS A 106 
AA5 3 4 N LEU A 107 ? N LEU A 107 O VAL A 110 ? O VAL A 110 
AA6 1 2 N TYR A 97  ? N TYR A 97  O LYS A 148 ? O LYS A 148 
AA6 2 3 N GLY A 147 ? N GLY A 147 O HIS A 156 ? O HIS A 156 
AA7 1 2 N GLN B 11  ? N GLN B 11  O SER B 18  ? O SER B 18  
AA8 1 2 N SER B 26  ? N SER B 26  O ALA B 33  ? O ALA B 33  
AA9 1 2 N GLN B 43  ? N GLN B 43  O GLY B 50  ? O GLY B 50  
AB1 1 2 N ILE B 116 ? N ILE B 116 O THR B 128 ? O THR B 128 
AB1 2 3 O VAL B 130 ? O VAL B 130 N ALA B 88  ? N ALA B 88  
AB1 3 4 O THR B 87  ? O THR B 87  N CYS B 80  ? N CYS B 80  
AB1 4 5 O PHE B 79  ? O PHE B 79  N PHE B 68  ? N PHE B 68  
AB1 5 6 N TYR B 69  ? N TYR B 69  O VAL B 163 ? O VAL B 163 
AB2 1 2 N TYR B 97  ? N TYR B 97  O LYS B 148 ? O LYS B 148 
AB2 2 3 O LYS B 144 ? O LYS B 144 N LYS B 106 ? N LYS B 106 
AB2 3 4 N LEU B 107 ? N LEU B 107 O VAL B 110 ? O VAL B 110 
AB3 1 2 N TYR B 97  ? N TYR B 97  O LYS B 148 ? O LYS B 148 
AB3 2 3 N GLY B 147 ? N GLY B 147 O HIS B 156 ? O HIS B 156 
AB4 1 2 N GLN C 11  ? N GLN C 11  O SER C 18  ? O SER C 18  
AB5 1 2 N SER C 26  ? N SER C 26  O ALA C 33  ? O ALA C 33  
AB6 1 2 N GLN C 43  ? N GLN C 43  O GLY C 50  ? O GLY C 50  
AB7 1 2 N ILE C 116 ? N ILE C 116 O THR C 128 ? O THR C 128 
AB7 2 3 O VAL C 130 ? O VAL C 130 N ALA C 88  ? N ALA C 88  
AB7 3 4 O THR C 87  ? O THR C 87  N CYS C 80  ? N CYS C 80  
AB7 4 5 O PHE C 79  ? O PHE C 79  N PHE C 68  ? N PHE C 68  
AB7 5 6 N TYR C 69  ? N TYR C 69  O VAL C 163 ? O VAL C 163 
AB8 1 2 N TYR C 97  ? N TYR C 97  O LYS C 148 ? O LYS C 148 
AB8 2 3 O LYS C 144 ? O LYS C 144 N LYS C 106 ? N LYS C 106 
AB8 3 4 N LEU C 107 ? N LEU C 107 O VAL C 110 ? O VAL C 110 
AB9 1 2 N TYR C 97  ? N TYR C 97  O LYS C 148 ? O LYS C 148 
AB9 2 3 N GLY C 147 ? N GLY C 147 O HIS C 156 ? O HIS C 156 
# 
_pdbx_entry_details.entry_id                   8UUS 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 SER A 7   ? ? -131.37 -149.18 
2 1 SER A 83  ? ? 49.39   -133.51 
3 1 SER B 7   ? ? -133.82 -131.46 
4 1 SER B 83  ? ? 50.86   -130.53 
5 1 ASN B 113 ? ? -101.87 -122.60 
6 1 SER C 7   ? ? -124.33 -140.75 
7 1 SER C 83  ? ? 51.85   -135.97 
8 1 SER C 134 ? ? -145.39 31.76   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x,-y,-z         
3 -x,y+1/2,-z+1/2 
4 -x,-y+1/2,z+1/2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 1   ? A GLY 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A SER 121 ? A SER 121 
4  1 Y 1 A GLY 122 ? A GLY 122 
5  1 Y 1 A SER 123 ? A SER 123 
6  1 Y 1 B GLY 1   ? B GLY 1   
7  1 Y 1 B ALA 2   ? B ALA 2   
8  1 Y 1 B LYS 3   ? B LYS 3   
9  1 Y 1 B VAL 4   ? B VAL 4   
10 1 Y 1 C GLY 1   ? C GLY 1   
11 1 Y 1 C ALA 2   ? C ALA 2   
12 1 Y 1 C LYS 3   ? C LYS 3   
13 1 Y 1 C VAL 4   ? C VAL 4   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CIT C1   C N N 74  
CIT O1   O N N 75  
CIT O2   O N N 76  
CIT C2   C N N 77  
CIT C3   C N N 78  
CIT O7   O N N 79  
CIT C4   C N N 80  
CIT C5   C N N 81  
CIT O3   O N N 82  
CIT O4   O N N 83  
CIT C6   C N N 84  
CIT O5   O N N 85  
CIT O6   O N N 86  
CIT HO2  H N N 87  
CIT H21  H N N 88  
CIT H22  H N N 89  
CIT HO7  H N N 90  
CIT H41  H N N 91  
CIT H42  H N N 92  
CIT HO4  H N N 93  
CIT HO6  H N N 94  
CYS N    N N N 95  
CYS CA   C N R 96  
CYS C    C N N 97  
CYS O    O N N 98  
CYS CB   C N N 99  
CYS SG   S N N 100 
CYS OXT  O N N 101 
CYS H    H N N 102 
CYS H2   H N N 103 
CYS HA   H N N 104 
CYS HB2  H N N 105 
CYS HB3  H N N 106 
CYS HG   H N N 107 
CYS HXT  H N N 108 
GLN N    N N N 109 
GLN CA   C N S 110 
GLN C    C N N 111 
GLN O    O N N 112 
GLN CB   C N N 113 
GLN CG   C N N 114 
GLN CD   C N N 115 
GLN OE1  O N N 116 
GLN NE2  N N N 117 
GLN OXT  O N N 118 
GLN H    H N N 119 
GLN H2   H N N 120 
GLN HA   H N N 121 
GLN HB2  H N N 122 
GLN HB3  H N N 123 
GLN HG2  H N N 124 
GLN HG3  H N N 125 
GLN HE21 H N N 126 
GLN HE22 H N N 127 
GLN HXT  H N N 128 
GLU N    N N N 129 
GLU CA   C N S 130 
GLU C    C N N 131 
GLU O    O N N 132 
GLU CB   C N N 133 
GLU CG   C N N 134 
GLU CD   C N N 135 
GLU OE1  O N N 136 
GLU OE2  O N N 137 
GLU OXT  O N N 138 
GLU H    H N N 139 
GLU H2   H N N 140 
GLU HA   H N N 141 
GLU HB2  H N N 142 
GLU HB3  H N N 143 
GLU HG2  H N N 144 
GLU HG3  H N N 145 
GLU HE2  H N N 146 
GLU HXT  H N N 147 
GLY N    N N N 148 
GLY CA   C N N 149 
GLY C    C N N 150 
GLY O    O N N 151 
GLY OXT  O N N 152 
GLY H    H N N 153 
GLY H2   H N N 154 
GLY HA2  H N N 155 
GLY HA3  H N N 156 
GLY HXT  H N N 157 
GOL C1   C N N 158 
GOL O1   O N N 159 
GOL C2   C N N 160 
GOL O2   O N N 161 
GOL C3   C N N 162 
GOL O3   O N N 163 
GOL H11  H N N 164 
GOL H12  H N N 165 
GOL HO1  H N N 166 
GOL H2   H N N 167 
GOL HO2  H N N 168 
GOL H31  H N N 169 
GOL H32  H N N 170 
GOL HO3  H N N 171 
HIS N    N N N 172 
HIS CA   C N S 173 
HIS C    C N N 174 
HIS O    O N N 175 
HIS CB   C N N 176 
HIS CG   C Y N 177 
HIS ND1  N Y N 178 
HIS CD2  C Y N 179 
HIS CE1  C Y N 180 
HIS NE2  N Y N 181 
HIS OXT  O N N 182 
HIS H    H N N 183 
HIS H2   H N N 184 
HIS HA   H N N 185 
HIS HB2  H N N 186 
HIS HB3  H N N 187 
HIS HD1  H N N 188 
HIS HD2  H N N 189 
HIS HE1  H N N 190 
HIS HE2  H N N 191 
HIS HXT  H N N 192 
HOH O    O N N 193 
HOH H1   H N N 194 
HOH H2   H N N 195 
ILE N    N N N 196 
ILE CA   C N S 197 
ILE C    C N N 198 
ILE O    O N N 199 
ILE CB   C N S 200 
ILE CG1  C N N 201 
ILE CG2  C N N 202 
ILE CD1  C N N 203 
ILE OXT  O N N 204 
ILE H    H N N 205 
ILE H2   H N N 206 
ILE HA   H N N 207 
ILE HB   H N N 208 
ILE HG12 H N N 209 
ILE HG13 H N N 210 
ILE HG21 H N N 211 
ILE HG22 H N N 212 
ILE HG23 H N N 213 
ILE HD11 H N N 214 
ILE HD12 H N N 215 
ILE HD13 H N N 216 
ILE HXT  H N N 217 
LEU N    N N N 218 
LEU CA   C N S 219 
LEU C    C N N 220 
LEU O    O N N 221 
LEU CB   C N N 222 
LEU CG   C N N 223 
LEU CD1  C N N 224 
LEU CD2  C N N 225 
LEU OXT  O N N 226 
LEU H    H N N 227 
LEU H2   H N N 228 
LEU HA   H N N 229 
LEU HB2  H N N 230 
LEU HB3  H N N 231 
LEU HG   H N N 232 
LEU HD11 H N N 233 
LEU HD12 H N N 234 
LEU HD13 H N N 235 
LEU HD21 H N N 236 
LEU HD22 H N N 237 
LEU HD23 H N N 238 
LEU HXT  H N N 239 
LYS N    N N N 240 
LYS CA   C N S 241 
LYS C    C N N 242 
LYS O    O N N 243 
LYS CB   C N N 244 
LYS CG   C N N 245 
LYS CD   C N N 246 
LYS CE   C N N 247 
LYS NZ   N N N 248 
LYS OXT  O N N 249 
LYS H    H N N 250 
LYS H2   H N N 251 
LYS HA   H N N 252 
LYS HB2  H N N 253 
LYS HB3  H N N 254 
LYS HG2  H N N 255 
LYS HG3  H N N 256 
LYS HD2  H N N 257 
LYS HD3  H N N 258 
LYS HE2  H N N 259 
LYS HE3  H N N 260 
LYS HZ1  H N N 261 
LYS HZ2  H N N 262 
LYS HZ3  H N N 263 
LYS HXT  H N N 264 
MET N    N N N 265 
MET CA   C N S 266 
MET C    C N N 267 
MET O    O N N 268 
MET CB   C N N 269 
MET CG   C N N 270 
MET SD   S N N 271 
MET CE   C N N 272 
MET OXT  O N N 273 
MET H    H N N 274 
MET H2   H N N 275 
MET HA   H N N 276 
MET HB2  H N N 277 
MET HB3  H N N 278 
MET HG2  H N N 279 
MET HG3  H N N 280 
MET HE1  H N N 281 
MET HE2  H N N 282 
MET HE3  H N N 283 
MET HXT  H N N 284 
NH4 N    N N N 285 
NH4 HN1  H N N 286 
NH4 HN2  H N N 287 
NH4 HN3  H N N 288 
NH4 HN4  H N N 289 
PHE N    N N N 290 
PHE CA   C N S 291 
PHE C    C N N 292 
PHE O    O N N 293 
PHE CB   C N N 294 
PHE CG   C Y N 295 
PHE CD1  C Y N 296 
PHE CD2  C Y N 297 
PHE CE1  C Y N 298 
PHE CE2  C Y N 299 
PHE CZ   C Y N 300 
PHE OXT  O N N 301 
PHE H    H N N 302 
PHE H2   H N N 303 
PHE HA   H N N 304 
PHE HB2  H N N 305 
PHE HB3  H N N 306 
PHE HD1  H N N 307 
PHE HD2  H N N 308 
PHE HE1  H N N 309 
PHE HE2  H N N 310 
PHE HZ   H N N 311 
PHE HXT  H N N 312 
PRO N    N N N 313 
PRO CA   C N S 314 
PRO C    C N N 315 
PRO O    O N N 316 
PRO CB   C N N 317 
PRO CG   C N N 318 
PRO CD   C N N 319 
PRO OXT  O N N 320 
PRO H    H N N 321 
PRO HA   H N N 322 
PRO HB2  H N N 323 
PRO HB3  H N N 324 
PRO HG2  H N N 325 
PRO HG3  H N N 326 
PRO HD2  H N N 327 
PRO HD3  H N N 328 
PRO HXT  H N N 329 
SER N    N N N 330 
SER CA   C N S 331 
SER C    C N N 332 
SER O    O N N 333 
SER CB   C N N 334 
SER OG   O N N 335 
SER OXT  O N N 336 
SER H    H N N 337 
SER H2   H N N 338 
SER HA   H N N 339 
SER HB2  H N N 340 
SER HB3  H N N 341 
SER HG   H N N 342 
SER HXT  H N N 343 
THR N    N N N 344 
THR CA   C N S 345 
THR C    C N N 346 
THR O    O N N 347 
THR CB   C N R 348 
THR OG1  O N N 349 
THR CG2  C N N 350 
THR OXT  O N N 351 
THR H    H N N 352 
THR H2   H N N 353 
THR HA   H N N 354 
THR HB   H N N 355 
THR HG1  H N N 356 
THR HG21 H N N 357 
THR HG22 H N N 358 
THR HG23 H N N 359 
THR HXT  H N N 360 
TRP N    N N N 361 
TRP CA   C N S 362 
TRP C    C N N 363 
TRP O    O N N 364 
TRP CB   C N N 365 
TRP CG   C Y N 366 
TRP CD1  C Y N 367 
TRP CD2  C Y N 368 
TRP NE1  N Y N 369 
TRP CE2  C Y N 370 
TRP CE3  C Y N 371 
TRP CZ2  C Y N 372 
TRP CZ3  C Y N 373 
TRP CH2  C Y N 374 
TRP OXT  O N N 375 
TRP H    H N N 376 
TRP H2   H N N 377 
TRP HA   H N N 378 
TRP HB2  H N N 379 
TRP HB3  H N N 380 
TRP HD1  H N N 381 
TRP HE1  H N N 382 
TRP HE3  H N N 383 
TRP HZ2  H N N 384 
TRP HZ3  H N N 385 
TRP HH2  H N N 386 
TRP HXT  H N N 387 
TYR N    N N N 388 
TYR CA   C N S 389 
TYR C    C N N 390 
TYR O    O N N 391 
TYR CB   C N N 392 
TYR CG   C Y N 393 
TYR CD1  C Y N 394 
TYR CD2  C Y N 395 
TYR CE1  C Y N 396 
TYR CE2  C Y N 397 
TYR CZ   C Y N 398 
TYR OH   O N N 399 
TYR OXT  O N N 400 
TYR H    H N N 401 
TYR H2   H N N 402 
TYR HA   H N N 403 
TYR HB2  H N N 404 
TYR HB3  H N N 405 
TYR HD1  H N N 406 
TYR HD2  H N N 407 
TYR HE1  H N N 408 
TYR HE2  H N N 409 
TYR HH   H N N 410 
TYR HXT  H N N 411 
VAL N    N N N 412 
VAL CA   C N S 413 
VAL C    C N N 414 
VAL O    O N N 415 
VAL CB   C N N 416 
VAL CG1  C N N 417 
VAL CG2  C N N 418 
VAL OXT  O N N 419 
VAL H    H N N 420 
VAL H2   H N N 421 
VAL HA   H N N 422 
VAL HB   H N N 423 
VAL HG11 H N N 424 
VAL HG12 H N N 425 
VAL HG13 H N N 426 
VAL HG21 H N N 427 
VAL HG22 H N N 428 
VAL HG23 H N N 429 
VAL HXT  H N N 430 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CIT C1  O1   doub N N 70  
CIT C1  O2   sing N N 71  
CIT C1  C2   sing N N 72  
CIT O2  HO2  sing N N 73  
CIT C2  C3   sing N N 74  
CIT C2  H21  sing N N 75  
CIT C2  H22  sing N N 76  
CIT C3  O7   sing N N 77  
CIT C3  C4   sing N N 78  
CIT C3  C6   sing N N 79  
CIT O7  HO7  sing N N 80  
CIT C4  C5   sing N N 81  
CIT C4  H41  sing N N 82  
CIT C4  H42  sing N N 83  
CIT C5  O3   doub N N 84  
CIT C5  O4   sing N N 85  
CIT O4  HO4  sing N N 86  
CIT C6  O5   doub N N 87  
CIT C6  O6   sing N N 88  
CIT O6  HO6  sing N N 89  
CYS N   CA   sing N N 90  
CYS N   H    sing N N 91  
CYS N   H2   sing N N 92  
CYS CA  C    sing N N 93  
CYS CA  CB   sing N N 94  
CYS CA  HA   sing N N 95  
CYS C   O    doub N N 96  
CYS C   OXT  sing N N 97  
CYS CB  SG   sing N N 98  
CYS CB  HB2  sing N N 99  
CYS CB  HB3  sing N N 100 
CYS SG  HG   sing N N 101 
CYS OXT HXT  sing N N 102 
GLN N   CA   sing N N 103 
GLN N   H    sing N N 104 
GLN N   H2   sing N N 105 
GLN CA  C    sing N N 106 
GLN CA  CB   sing N N 107 
GLN CA  HA   sing N N 108 
GLN C   O    doub N N 109 
GLN C   OXT  sing N N 110 
GLN CB  CG   sing N N 111 
GLN CB  HB2  sing N N 112 
GLN CB  HB3  sing N N 113 
GLN CG  CD   sing N N 114 
GLN CG  HG2  sing N N 115 
GLN CG  HG3  sing N N 116 
GLN CD  OE1  doub N N 117 
GLN CD  NE2  sing N N 118 
GLN NE2 HE21 sing N N 119 
GLN NE2 HE22 sing N N 120 
GLN OXT HXT  sing N N 121 
GLU N   CA   sing N N 122 
GLU N   H    sing N N 123 
GLU N   H2   sing N N 124 
GLU CA  C    sing N N 125 
GLU CA  CB   sing N N 126 
GLU CA  HA   sing N N 127 
GLU C   O    doub N N 128 
GLU C   OXT  sing N N 129 
GLU CB  CG   sing N N 130 
GLU CB  HB2  sing N N 131 
GLU CB  HB3  sing N N 132 
GLU CG  CD   sing N N 133 
GLU CG  HG2  sing N N 134 
GLU CG  HG3  sing N N 135 
GLU CD  OE1  doub N N 136 
GLU CD  OE2  sing N N 137 
GLU OE2 HE2  sing N N 138 
GLU OXT HXT  sing N N 139 
GLY N   CA   sing N N 140 
GLY N   H    sing N N 141 
GLY N   H2   sing N N 142 
GLY CA  C    sing N N 143 
GLY CA  HA2  sing N N 144 
GLY CA  HA3  sing N N 145 
GLY C   O    doub N N 146 
GLY C   OXT  sing N N 147 
GLY OXT HXT  sing N N 148 
GOL C1  O1   sing N N 149 
GOL C1  C2   sing N N 150 
GOL C1  H11  sing N N 151 
GOL C1  H12  sing N N 152 
GOL O1  HO1  sing N N 153 
GOL C2  O2   sing N N 154 
GOL C2  C3   sing N N 155 
GOL C2  H2   sing N N 156 
GOL O2  HO2  sing N N 157 
GOL C3  O3   sing N N 158 
GOL C3  H31  sing N N 159 
GOL C3  H32  sing N N 160 
GOL O3  HO3  sing N N 161 
HIS N   CA   sing N N 162 
HIS N   H    sing N N 163 
HIS N   H2   sing N N 164 
HIS CA  C    sing N N 165 
HIS CA  CB   sing N N 166 
HIS CA  HA   sing N N 167 
HIS C   O    doub N N 168 
HIS C   OXT  sing N N 169 
HIS CB  CG   sing N N 170 
HIS CB  HB2  sing N N 171 
HIS CB  HB3  sing N N 172 
HIS CG  ND1  sing Y N 173 
HIS CG  CD2  doub Y N 174 
HIS ND1 CE1  doub Y N 175 
HIS ND1 HD1  sing N N 176 
HIS CD2 NE2  sing Y N 177 
HIS CD2 HD2  sing N N 178 
HIS CE1 NE2  sing Y N 179 
HIS CE1 HE1  sing N N 180 
HIS NE2 HE2  sing N N 181 
HIS OXT HXT  sing N N 182 
HOH O   H1   sing N N 183 
HOH O   H2   sing N N 184 
ILE N   CA   sing N N 185 
ILE N   H    sing N N 186 
ILE N   H2   sing N N 187 
ILE CA  C    sing N N 188 
ILE CA  CB   sing N N 189 
ILE CA  HA   sing N N 190 
ILE C   O    doub N N 191 
ILE C   OXT  sing N N 192 
ILE CB  CG1  sing N N 193 
ILE CB  CG2  sing N N 194 
ILE CB  HB   sing N N 195 
ILE CG1 CD1  sing N N 196 
ILE CG1 HG12 sing N N 197 
ILE CG1 HG13 sing N N 198 
ILE CG2 HG21 sing N N 199 
ILE CG2 HG22 sing N N 200 
ILE CG2 HG23 sing N N 201 
ILE CD1 HD11 sing N N 202 
ILE CD1 HD12 sing N N 203 
ILE CD1 HD13 sing N N 204 
ILE OXT HXT  sing N N 205 
LEU N   CA   sing N N 206 
LEU N   H    sing N N 207 
LEU N   H2   sing N N 208 
LEU CA  C    sing N N 209 
LEU CA  CB   sing N N 210 
LEU CA  HA   sing N N 211 
LEU C   O    doub N N 212 
LEU C   OXT  sing N N 213 
LEU CB  CG   sing N N 214 
LEU CB  HB2  sing N N 215 
LEU CB  HB3  sing N N 216 
LEU CG  CD1  sing N N 217 
LEU CG  CD2  sing N N 218 
LEU CG  HG   sing N N 219 
LEU CD1 HD11 sing N N 220 
LEU CD1 HD12 sing N N 221 
LEU CD1 HD13 sing N N 222 
LEU CD2 HD21 sing N N 223 
LEU CD2 HD22 sing N N 224 
LEU CD2 HD23 sing N N 225 
LEU OXT HXT  sing N N 226 
LYS N   CA   sing N N 227 
LYS N   H    sing N N 228 
LYS N   H2   sing N N 229 
LYS CA  C    sing N N 230 
LYS CA  CB   sing N N 231 
LYS CA  HA   sing N N 232 
LYS C   O    doub N N 233 
LYS C   OXT  sing N N 234 
LYS CB  CG   sing N N 235 
LYS CB  HB2  sing N N 236 
LYS CB  HB3  sing N N 237 
LYS CG  CD   sing N N 238 
LYS CG  HG2  sing N N 239 
LYS CG  HG3  sing N N 240 
LYS CD  CE   sing N N 241 
LYS CD  HD2  sing N N 242 
LYS CD  HD3  sing N N 243 
LYS CE  NZ   sing N N 244 
LYS CE  HE2  sing N N 245 
LYS CE  HE3  sing N N 246 
LYS NZ  HZ1  sing N N 247 
LYS NZ  HZ2  sing N N 248 
LYS NZ  HZ3  sing N N 249 
LYS OXT HXT  sing N N 250 
MET N   CA   sing N N 251 
MET N   H    sing N N 252 
MET N   H2   sing N N 253 
MET CA  C    sing N N 254 
MET CA  CB   sing N N 255 
MET CA  HA   sing N N 256 
MET C   O    doub N N 257 
MET C   OXT  sing N N 258 
MET CB  CG   sing N N 259 
MET CB  HB2  sing N N 260 
MET CB  HB3  sing N N 261 
MET CG  SD   sing N N 262 
MET CG  HG2  sing N N 263 
MET CG  HG3  sing N N 264 
MET SD  CE   sing N N 265 
MET CE  HE1  sing N N 266 
MET CE  HE2  sing N N 267 
MET CE  HE3  sing N N 268 
MET OXT HXT  sing N N 269 
NH4 N   HN1  sing N N 270 
NH4 N   HN2  sing N N 271 
NH4 N   HN3  sing N N 272 
NH4 N   HN4  sing N N 273 
PHE N   CA   sing N N 274 
PHE N   H    sing N N 275 
PHE N   H2   sing N N 276 
PHE CA  C    sing N N 277 
PHE CA  CB   sing N N 278 
PHE CA  HA   sing N N 279 
PHE C   O    doub N N 280 
PHE C   OXT  sing N N 281 
PHE CB  CG   sing N N 282 
PHE CB  HB2  sing N N 283 
PHE CB  HB3  sing N N 284 
PHE CG  CD1  doub Y N 285 
PHE CG  CD2  sing Y N 286 
PHE CD1 CE1  sing Y N 287 
PHE CD1 HD1  sing N N 288 
PHE CD2 CE2  doub Y N 289 
PHE CD2 HD2  sing N N 290 
PHE CE1 CZ   doub Y N 291 
PHE CE1 HE1  sing N N 292 
PHE CE2 CZ   sing Y N 293 
PHE CE2 HE2  sing N N 294 
PHE CZ  HZ   sing N N 295 
PHE OXT HXT  sing N N 296 
PRO N   CA   sing N N 297 
PRO N   CD   sing N N 298 
PRO N   H    sing N N 299 
PRO CA  C    sing N N 300 
PRO CA  CB   sing N N 301 
PRO CA  HA   sing N N 302 
PRO C   O    doub N N 303 
PRO C   OXT  sing N N 304 
PRO CB  CG   sing N N 305 
PRO CB  HB2  sing N N 306 
PRO CB  HB3  sing N N 307 
PRO CG  CD   sing N N 308 
PRO CG  HG2  sing N N 309 
PRO CG  HG3  sing N N 310 
PRO CD  HD2  sing N N 311 
PRO CD  HD3  sing N N 312 
PRO OXT HXT  sing N N 313 
SER N   CA   sing N N 314 
SER N   H    sing N N 315 
SER N   H2   sing N N 316 
SER CA  C    sing N N 317 
SER CA  CB   sing N N 318 
SER CA  HA   sing N N 319 
SER C   O    doub N N 320 
SER C   OXT  sing N N 321 
SER CB  OG   sing N N 322 
SER CB  HB2  sing N N 323 
SER CB  HB3  sing N N 324 
SER OG  HG   sing N N 325 
SER OXT HXT  sing N N 326 
THR N   CA   sing N N 327 
THR N   H    sing N N 328 
THR N   H2   sing N N 329 
THR CA  C    sing N N 330 
THR CA  CB   sing N N 331 
THR CA  HA   sing N N 332 
THR C   O    doub N N 333 
THR C   OXT  sing N N 334 
THR CB  OG1  sing N N 335 
THR CB  CG2  sing N N 336 
THR CB  HB   sing N N 337 
THR OG1 HG1  sing N N 338 
THR CG2 HG21 sing N N 339 
THR CG2 HG22 sing N N 340 
THR CG2 HG23 sing N N 341 
THR OXT HXT  sing N N 342 
TRP N   CA   sing N N 343 
TRP N   H    sing N N 344 
TRP N   H2   sing N N 345 
TRP CA  C    sing N N 346 
TRP CA  CB   sing N N 347 
TRP CA  HA   sing N N 348 
TRP C   O    doub N N 349 
TRP C   OXT  sing N N 350 
TRP CB  CG   sing N N 351 
TRP CB  HB2  sing N N 352 
TRP CB  HB3  sing N N 353 
TRP CG  CD1  doub Y N 354 
TRP CG  CD2  sing Y N 355 
TRP CD1 NE1  sing Y N 356 
TRP CD1 HD1  sing N N 357 
TRP CD2 CE2  doub Y N 358 
TRP CD2 CE3  sing Y N 359 
TRP NE1 CE2  sing Y N 360 
TRP NE1 HE1  sing N N 361 
TRP CE2 CZ2  sing Y N 362 
TRP CE3 CZ3  doub Y N 363 
TRP CE3 HE3  sing N N 364 
TRP CZ2 CH2  doub Y N 365 
TRP CZ2 HZ2  sing N N 366 
TRP CZ3 CH2  sing Y N 367 
TRP CZ3 HZ3  sing N N 368 
TRP CH2 HH2  sing N N 369 
TRP OXT HXT  sing N N 370 
TYR N   CA   sing N N 371 
TYR N   H    sing N N 372 
TYR N   H2   sing N N 373 
TYR CA  C    sing N N 374 
TYR CA  CB   sing N N 375 
TYR CA  HA   sing N N 376 
TYR C   O    doub N N 377 
TYR C   OXT  sing N N 378 
TYR CB  CG   sing N N 379 
TYR CB  HB2  sing N N 380 
TYR CB  HB3  sing N N 381 
TYR CG  CD1  doub Y N 382 
TYR CG  CD2  sing Y N 383 
TYR CD1 CE1  sing Y N 384 
TYR CD1 HD1  sing N N 385 
TYR CD2 CE2  doub Y N 386 
TYR CD2 HD2  sing N N 387 
TYR CE1 CZ   doub Y N 388 
TYR CE1 HE1  sing N N 389 
TYR CE2 CZ   sing Y N 390 
TYR CE2 HE2  sing N N 391 
TYR CZ  OH   sing N N 392 
TYR OH  HH   sing N N 393 
TYR OXT HXT  sing N N 394 
VAL N   CA   sing N N 395 
VAL N   H    sing N N 396 
VAL N   H2   sing N N 397 
VAL CA  C    sing N N 398 
VAL CA  CB   sing N N 399 
VAL CA  HA   sing N N 400 
VAL C   O    doub N N 401 
VAL C   OXT  sing N N 402 
VAL CB  CG1  sing N N 403 
VAL CB  CG2  sing N N 404 
VAL CB  HB   sing N N 405 
VAL CG1 HG11 sing N N 406 
VAL CG1 HG12 sing N N 407 
VAL CG1 HG13 sing N N 408 
VAL CG2 HG21 sing N N 409 
VAL CG2 HG22 sing N N 410 
VAL CG2 HG23 sing N N 411 
VAL OXT HXT  sing N N 412 
# 
_pdbx_audit_support.funding_organization   'Ministry of Business, Innovation and Employment (New Zealand)' 
_pdbx_audit_support.country                'New Zealand' 
_pdbx_audit_support.grant_number           C10X1805 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          'In-house partially refined experimental model' 
# 
_space_group.name_H-M_alt     'P 2 21 21' 
_space_group.name_Hall        'P 2 2ab (z,x,y)' 
_space_group.IT_number        18 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8UUS 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.016917 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014654 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008986 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LYS A 1 3   ? 39.20068 26.34473  -21.81643 1.000 27.57391 ? 3   LYS A N   1 
ATOM   2    C CA  . LYS A 1 3   ? 40.50067 26.34418  -21.15676 1.000 28.56268 ? 3   LYS A CA  1 
ATOM   3    C C   . LYS A 1 3   ? 40.51726 25.44771  -19.91564 1.000 31.56318 ? 3   LYS A C   1 
ATOM   4    O O   . LYS A 1 3   ? 41.51641 24.77309  -19.65276 1.000 32.28241 ? 3   LYS A O   1 
ATOM   5    C CB  . LYS A 1 3   ? 40.93027 27.77191  -20.79760 1.000 30.08727 ? 3   LYS A CB  1 
ATOM   6    N N   . VAL A 1 4   ? 39.42739 25.43148  -19.14965 1.000 26.83229 ? 4   VAL A N   1 
ATOM   7    C CA  . VAL A 1 4   ? 39.35892 24.55879  -17.97842 1.000 26.19751 ? 4   VAL A CA  1 
ATOM   8    C C   . VAL A 1 4   ? 37.89811 24.29967  -17.63559 1.000 23.03660 ? 4   VAL A C   1 
ATOM   9    O O   . VAL A 1 4   ? 37.04889 25.18432  -17.76123 1.000 20.93597 ? 4   VAL A O   1 
ATOM   10   C CB  . VAL A 1 4   ? 40.15910 25.13661  -16.78313 1.000 26.53764 ? 4   VAL A CB  1 
ATOM   11   C CG1 . VAL A 1 4   ? 39.45718 26.35182  -16.19169 1.000 26.77294 ? 4   VAL A CG1 1 
ATOM   12   C CG2 . VAL A 1 4   ? 40.36862 24.07364  -15.72052 1.000 27.07573 ? 4   VAL A CG2 1 
ATOM   13   N N   . GLU A 1 5   ? 37.61153 23.06469  -17.20779 1.000 21.07071 ? 5   GLU A N   1 
ATOM   14   C CA  . GLU A 1 5   ? 36.30235 22.67522  -16.67121 1.000 21.29428 ? 5   GLU A CA  1 
ATOM   15   C C   . GLU A 1 5   ? 36.60197 21.84664  -15.42264 1.000 22.36890 ? 5   GLU A C   1 
ATOM   16   O O   . GLU A 1 5   ? 36.78419 20.62646  -15.50428 1.000 21.79315 ? 5   GLU A O   1 
ATOM   17   C CB  . GLU A 1 5   ? 35.47875 21.89324  -17.68900 1.000 21.71943 ? 5   GLU A CB  1 
ATOM   18   C CG  . GLU A 1 5   ? 35.21888 22.61790  -19.02767 1.000 25.37560 ? 5   GLU A CG  1 
ATOM   19   C CD  . GLU A 1 5   ? 34.29557 23.83289  -18.92608 1.000 26.70786 ? 5   GLU A CD  1 
ATOM   20   O OE1 . GLU A 1 5   ? 33.74990 24.11476  -17.84395 1.000 23.38238 ? 5   GLU A OE1 1 
ATOM   21   O OE2 . GLU A 1 5   ? 34.11219 24.52151  -19.95134 1.000 26.65241 ? 5   GLU A OE2 1 
ATOM   22   N N   . ALA A 1 6   ? 36.67471 22.51982  -14.27790 1.000 17.32620 ? 6   ALA A N   1 
ATOM   23   C CA  . ALA A 1 6   ? 37.08524 21.90522  -13.02200 1.000 16.30173 ? 6   ALA A CA  1 
ATOM   24   C C   . ALA A 1 6   ? 35.88742 21.67544  -12.11610 1.000 17.77775 ? 6   ALA A C   1 
ATOM   25   O O   . ALA A 1 6   ? 34.91649 22.44045  -12.12396 1.000 18.77950 ? 6   ALA A O   1 
ATOM   26   C CB  . ALA A 1 6   ? 38.10668 22.78505  -12.29101 1.000 16.46566 ? 6   ALA A CB  1 
ATOM   27   N N   . SER A 1 7   ? 35.96740 20.60356  -11.32911 1.000 15.16534 ? 7   SER A N   1 
ATOM   28   C CA  . SER A 1 7   ? 34.86024 20.19256  -10.47870 1.000 15.38437 ? 7   SER A CA  1 
ATOM   29   C C   . SER A 1 7   ? 35.34156 19.92197  -9.05459  1.000 15.83572 ? 7   SER A C   1 
ATOM   30   O O   . SER A 1 7   ? 36.30901 20.54484  -8.59810  1.000 15.64465 ? 7   SER A O   1 
ATOM   31   C CB  . SER A 1 7   ? 34.18846 18.96489  -11.09944 1.000 16.56447 ? 7   SER A CB  1 
ATOM   32   O OG  . SER A 1 7   ? 32.96123 18.64962  -10.47535 1.000 15.69889 ? 7   SER A OG  1 
ATOM   33   N N   . LYS A 1 8   ? 34.68540 18.99287  -8.35587  1.000 15.83126 ? 8   LYS A N   1 
ATOM   34   C CA  . LYS A 1 8   ? 34.90894 18.82176  -6.92207  1.000 14.87175 ? 8   LYS A CA  1 
ATOM   35   C C   . LYS A 1 8   ? 36.37003 18.51254  -6.58483  1.000 15.73281 ? 8   LYS A C   1 
ATOM   36   O O   . LYS A 1 8   ? 37.03522 17.70970  -7.24971  1.000 14.72659 ? 8   LYS A O   1 
ATOM   37   C CB  . LYS A 1 8   ? 33.96713 17.74671  -6.36009  1.000 15.17844 ? 8   LYS A CB  1 
ATOM   38   C CG  . LYS A 1 8   ? 34.08299 16.37677  -7.02265  1.000 17.10556 ? 8   LYS A CG  1 
ATOM   39   C CD  . LYS A 1 8   ? 33.14284 15.36224  -6.39070  1.000 17.07501 ? 8   LYS A CD  1 
ATOM   40   C CE  . LYS A 1 8   ? 33.24487 14.04427  -7.13070  1.000 18.39318 ? 8   LYS A CE  1 
ATOM   41   N NZ  . LYS A 1 8   ? 32.24958 13.04224  -6.64159  1.000 20.64580 ? 8   LYS A NZ  1 
ATOM   42   N N   . GLY A 1 9   ? 36.86978 19.15462  -5.52715  1.000 13.24268 ? 9   GLY A N   1 
ATOM   43   C CA  . GLY A 1 9   ? 38.22966 18.95262  -5.07048  1.000 13.40619 ? 9   GLY A CA  1 
ATOM   44   C C   . GLY A 1 9   ? 39.23839 19.91533  -5.65664  1.000 13.64391 ? 9   GLY A C   1 
ATOM   45   O O   . GLY A 1 9   ? 40.33698 20.04753  -5.11204  1.000 13.62887 ? 9   GLY A O   1 
ATOM   46   N N   . LEU A 1 10  ? 38.88898 20.59081  -6.74429  1.000 14.86551 ? 10  LEU A N   1 
ATOM   47   C CA  . LEU A 1 10  ? 39.74596 21.53339  -7.43498  1.000 14.43790 ? 10  LEU A CA  1 
ATOM   48   C C   . LEU A 1 10  ? 39.17842 22.94113  -7.31092  1.000 15.02583 ? 10  LEU A C   1 
ATOM   49   O O   . LEU A 1 10  ? 37.98769 23.14367  -7.07675  1.000 15.98828 ? 10  LEU A O   1 
ATOM   50   C CB  . LEU A 1 10  ? 39.88065 21.13693  -8.91588  1.000 13.82271 ? 10  LEU A CB  1 
ATOM   51   C CG  . LEU A 1 10  ? 40.50165 19.75020  -9.11942  1.000 13.33324 ? 10  LEU A CG  1 
ATOM   52   C CD1 . LEU A 1 10  ? 40.54775 19.43179  -10.60610 1.000 17.37903 ? 10  LEU A CD1 1 
ATOM   53   C CD2 . LEU A 1 10  ? 41.93217 19.67812  -8.53785  1.000 13.82807 ? 10  LEU A CD2 1 
ATOM   54   N N   . GLN A 1 11  ? 40.06307 23.92383  -7.44749  1.000 13.53035 ? 11  GLN A N   1 
ATOM   55   C CA  . GLN A 1 11  ? 39.66288 25.32308  -7.51969  1.000 13.66962 ? 11  GLN A CA  1 
ATOM   56   C C   . GLN A 1 11  ? 40.53681 26.00243  -8.56287  1.000 14.14349 ? 11  GLN A C   1 
ATOM   57   O O   . GLN A 1 11  ? 41.62356 25.52156  -8.89023  1.000 15.61371 ? 11  GLN A O   1 
ATOM   58   C CB  . GLN A 1 11  ? 39.80732 26.00661  -6.16004  1.000 17.93839 ? 11  GLN A CB  1 
ATOM   59   C CG  . GLN A 1 11  ? 41.24933 26.11518  -5.71380  1.000 18.06132 ? 11  GLN A CG  1 
ATOM   60   C CD  . GLN A 1 11  ? 41.41329 26.45627  -4.24649  1.000 20.91784 ? 11  GLN A CD  1 
ATOM   61   O OE1 . GLN A 1 11  ? 40.45064 26.76816  -3.55154  1.000 23.94078 ? 11  GLN A OE1 1 
ATOM   62   N NE2 . GLN A 1 11  ? 42.65248 26.39900  -3.76898  1.000 26.28385 ? 11  GLN A NE2 1 
ATOM   63   N N   . VAL A 1 12  ? 40.04907 27.11082  -9.10448  1.000 17.79672 ? 12  VAL A N   1 
ATOM   64   C CA  . VAL A 1 12  ? 40.76747 27.84687  -10.13530 1.000 18.21865 ? 12  VAL A CA  1 
ATOM   65   C C   . VAL A 1 12  ? 40.91313 29.29501  -9.69484  1.000 19.11283 ? 12  VAL A C   1 
ATOM   66   O O   . VAL A 1 12  ? 39.91928 29.96442  -9.39047  1.000 22.51563 ? 12  VAL A O   1 
ATOM   67   C CB  . VAL A 1 12  ? 40.06480 27.76837  -11.50400 1.000 18.51139 ? 12  VAL A CB  1 
ATOM   68   C CG1 . VAL A 1 12  ? 40.89629 28.49790  -12.54932 1.000 20.86362 ? 12  VAL A CG1 1 
ATOM   69   C CG2 . VAL A 1 12  ? 39.82078 26.32245  -11.92125 1.000 19.45035 ? 12  VAL A CG2 1 
ATOM   70   N N   . THR A 1 13  ? 42.15080 29.78017  -9.67688  1.000 19.08105 ? 13  THR A N   1 
ATOM   71   C CA  . THR A 1 13  ? 42.45366 31.16437  -9.35237  1.000 21.88236 ? 13  THR A CA  1 
ATOM   72   C C   . THR A 1 13  ? 43.34932 31.73601  -10.44244 1.000 20.09351 ? 13  THR A C   1 
ATOM   73   O O   . THR A 1 13  ? 43.56401 31.10087  -11.48108 1.000 19.63338 ? 13  THR A O   1 
ATOM   74   C CB  . THR A 1 13  ? 43.15764 31.24984  -7.99403  1.000 21.52166 ? 13  THR A CB  1 
ATOM   75   O OG1 . THR A 1 13  ? 44.46001 30.64868  -8.08418  1.000 21.94895 ? 13  THR A OG1 1 
ATOM   76   C CG2 . THR A 1 13  ? 42.35498 30.54481  -6.91006  1.000 24.75435 ? 13  THR A CG2 1 
ATOM   77   N N   . ALA A 1 14  ? 43.88306 32.93742  -10.22304 1.000 25.12672 ? 14  ALA A N   1 
ATOM   78   C CA  . ALA A 1 14  ? 44.79495 33.50239  -11.20811 1.000 23.00930 ? 14  ALA A CA  1 
ATOM   79   C C   . ALA A 1 14  ? 46.06212 32.67226  -11.35706 1.000 22.50102 ? 14  ALA A C   1 
ATOM   80   O O   . ALA A 1 14  ? 46.73677 32.77250  -12.38718 1.000 25.79370 ? 14  ALA A O   1 
ATOM   81   C CB  . ALA A 1 14  ? 45.15869 34.93207  -10.82424 1.000 24.53496 ? 14  ALA A CB  1 
ATOM   82   N N   . SER A 1 15  ? 46.39308 31.86519  -10.34781 1.000 20.49724 ? 15  SER A N   1 
ATOM   83   C CA  . SER A 1 15  ? 47.56419 30.99282  -10.35656 1.000 18.70317 ? 15  SER A CA  1 
ATOM   84   C C   . SER A 1 15  ? 47.31042 29.68313  -11.08931 1.000 20.57422 ? 15  SER A C   1 
ATOM   85   O O   . SER A 1 15  ? 48.24385 28.89376  -11.26235 1.000 20.51850 ? 15  SER A O   1 
ATOM   86   C CB  . SER A 1 15  ? 47.95997 30.68199  -8.91510  1.000 21.43053 ? 15  SER A CB  1 
ATOM   87   O OG  . SER A 1 15  ? 48.52676 31.81548  -8.28926  1.000 30.08102 ? 15  SER A OG  1 
ATOM   88   N N   . GLY A 1 16  ? 46.08237 29.42934  -11.50556 1.000 19.17707 ? 16  GLY A N   1 
ATOM   89   C CA  . GLY A 1 16  ? 45.74966 28.21805  -12.21348 1.000 17.86191 ? 16  GLY A CA  1 
ATOM   90   C C   . GLY A 1 16  ? 44.82907 27.32486  -11.40939 1.000 16.73376 ? 16  GLY A C   1 
ATOM   91   O O   . GLY A 1 16  ? 44.11095 27.76551  -10.50906 1.000 17.13739 ? 16  GLY A O   1 
ATOM   92   N N   . VAL A 1 17  ? 44.85900 26.04078  -11.74793 1.000 16.08489 ? 17  VAL A N   1 
ATOM   93   C CA  . VAL A 1 17  ? 44.04115 25.05416  -11.05757 1.000 14.71949 ? 17  VAL A CA  1 
ATOM   94   C C   . VAL A 1 17  ? 44.86715 24.40760  -9.95284  1.000 15.28464 ? 17  VAL A C   1 
ATOM   95   O O   . VAL A 1 17  ? 45.99869 23.95843  -10.18304 1.000 16.00877 ? 17  VAL A O   1 
ATOM   96   C CB  . VAL A 1 17  ? 43.47377 24.01101  -12.03608 1.000 17.26805 ? 17  VAL A CB  1 
ATOM   97   C CG1 . VAL A 1 17  ? 44.56353 23.29161  -12.79619 1.000 22.31789 ? 17  VAL A CG1 1 
ATOM   98   C CG2 . VAL A 1 17  ? 42.55235 23.02985  -11.29798 1.000 19.15458 ? 17  VAL A CG2 1 
ATOM   99   N N   . SER A 1 18  ? 44.31537 24.39166  -8.74284  1.000 15.16304 ? 18  SER A N   1 
ATOM   100  C CA  . SER A 1 18  ? 44.96564 23.80336  -7.57883  1.000 13.71163 ? 18  SER A CA  1 
ATOM   101  C C   . SER A 1 18  ? 43.97265 22.91088  -6.84704  1.000 13.94618 ? 18  SER A C   1 
ATOM   102  O O   . SER A 1 18  ? 42.75209 22.98759  -7.05800  1.000 14.24449 ? 18  SER A O   1 
ATOM   103  C CB  . SER A 1 18  ? 45.47512 24.88937  -6.61588  1.000 16.19186 ? 18  SER A CB  1 
ATOM   104  O OG  . SER A 1 18  ? 44.40648 25.74508  -6.21562  1.000 17.72547 ? 18  SER A OG  1 
ATOM   105  N N   . VAL A 1 19  ? 44.50378 22.05969  -5.97508  1.000 13.41131 ? 19  VAL A N   1 
ATOM   106  C CA  . VAL A 1 19  ? 43.66377 21.26710  -5.08690  1.000 14.12027 ? 19  VAL A CA  1 
ATOM   107  C C   . VAL A 1 19  ? 43.13570 22.16891  -3.97803  1.000 13.93603 ? 19  VAL A C   1 
ATOM   108  O O   . VAL A 1 19  ? 43.89203 22.93865  -3.36176  1.000 14.34140 ? 19  VAL A O   1 
ATOM   109  C CB  . VAL A 1 19  ? 44.44527 20.07366  -4.52156  1.000 13.22429 ? 19  VAL A CB  1 
ATOM   110  C CG1 . VAL A 1 19  ? 43.57033 19.30026  -3.52223  1.000 13.16942 ? 19  VAL A CG1 1 
ATOM   111  C CG2 . VAL A 1 19  ? 44.91706 19.16970  -5.65758  1.000 14.10983 ? 19  VAL A CG2 1 
ATOM   112  N N   . GLN A 1 20  ? 41.82425 22.10718  -3.75103  1.000 14.12526 ? 20  GLN A N   1 
ATOM   113  C CA  . GLN A 1 20  ? 41.18166 22.86334  -2.68504  1.000 13.54058 ? 20  GLN A CA  1 
ATOM   114  C C   . GLN A 1 20  ? 41.27232 22.05924  -1.39711  1.000 12.66692 ? 20  GLN A C   1 
ATOM   115  O O   . GLN A 1 20  ? 40.81129 20.91263  -1.34035  1.000 14.89384 ? 20  GLN A O   1 
ATOM   116  C CB  . GLN A 1 20  ? 39.72184 23.13784  -3.04027  1.000 15.12996 ? 20  GLN A CB  1 
ATOM   117  C CG  . GLN A 1 20  ? 38.99028 23.93237  -1.97545  1.000 15.62500 ? 20  GLN A CG  1 
ATOM   118  C CD  . GLN A 1 20  ? 37.51292 24.10052  -2.28717  1.000 20.06004 ? 20  GLN A CD  1 
ATOM   119  O OE1 . GLN A 1 20  ? 37.09079 23.93246  -3.42573  1.000 21.91046 ? 20  GLN A OE1 1 
ATOM   120  N NE2 . GLN A 1 20  ? 36.72153 24.42760  -1.27145  1.000 21.49522 ? 20  GLN A NE2 1 
ATOM   121  N N   . ALA A 1 21  ? 41.85231 22.65924  -0.36305  1.000 13.31932 ? 21  ALA A N   1 
ATOM   122  C CA  . ALA A 1 21  ? 42.02026 21.98104  0.91714   1.000 13.52201 ? 21  ALA A CA  1 
ATOM   123  C C   . ALA A 1 21  ? 40.74675 22.07765  1.75429   1.000 16.02407 ? 21  ALA A C   1 
ATOM   124  O O   . ALA A 1 21  ? 40.27404 23.18481  2.05101   1.000 17.28233 ? 21  ALA A O   1 
ATOM   125  C CB  . ALA A 1 21  ? 43.19293 22.59947  1.67636   1.000 15.19052 ? 21  ALA A CB  1 
ATOM   126  N N   . GLY A 1 22  ? 40.20421 20.91784  2.13913   1.000 14.86550 ? 22  GLY A N   1 
ATOM   127  C CA  . GLY A 1 22  ? 39.15171 20.83269  3.12901   1.000 14.31433 ? 22  GLY A CA  1 
ATOM   128  C C   . GLY A 1 22  ? 39.68502 20.41191  4.49146   1.000 14.81089 ? 22  GLY A C   1 
ATOM   129  O O   . GLY A 1 22  ? 40.88878 20.43546  4.75674   1.000 15.18170 ? 22  GLY A O   1 
ATOM   130  N N   . ASP A 1 23  ? 38.75218 20.03353  5.37554   1.000 14.36264 ? 23  ASP A N   1 
ATOM   131  C CA  . ASP A 1 23  ? 39.10938 19.65813  6.74531   1.000 13.84971 ? 23  ASP A CA  1 
ATOM   132  C C   . ASP A 1 23  ? 40.13717 18.52655  6.75178   1.000 13.74764 ? 23  ASP A C   1 
ATOM   133  O O   . ASP A 1 23  ? 39.93879 17.48286  6.11921   1.000 14.32487 ? 23  ASP A O   1 
ATOM   134  C CB  . ASP A 1 23  ? 37.87331 19.18290  7.51918   1.000 14.57117 ? 23  ASP A CB  1 
ATOM   135  C CG  . ASP A 1 23  ? 36.94343 20.31126  7.94384   1.000 18.26055 ? 23  ASP A CG  1 
ATOM   136  O OD1 . ASP A 1 23  ? 37.21626 21.49828  7.66471   1.000 18.45629 ? 23  ASP A OD1 1 
ATOM   137  O OD2 . ASP A 1 23  ? 35.92445 19.97232  8.59026   1.000 20.47672 ? 23  ASP A OD2 1 
ATOM   138  N N   . GLY A 1 24  ? 41.22224 18.72116  7.50098   1.000 11.42807 ? 24  GLY A N   1 
ATOM   139  C CA  . GLY A 1 24  ? 42.23873 17.69583  7.64830   1.000 12.98364 ? 24  GLY A CA  1 
ATOM   140  C C   . GLY A 1 24  ? 43.24685 17.59666  6.52447   1.000 12.85272 ? 24  GLY A C   1 
ATOM   141  O O   . GLY A 1 24  ? 44.03801 16.64259  6.51404   1.000 13.37227 ? 24  GLY A O   1 
ATOM   142  N N   . ILE A 1 25  ? 43.24758 18.54689  5.58463   1.000 13.91164 ? 25  ILE A N   1 
ATOM   143  C CA  . ILE A 1 25  ? 44.11124 18.49992  4.41090   1.000 12.56211 ? 25  ILE A CA  1 
ATOM   144  C C   . ILE A 1 25  ? 44.83780 19.83183  4.28169   1.000 13.32301 ? 25  ILE A C   1 
ATOM   145  O O   . ILE A 1 25  ? 44.25887 20.89755  4.52652   1.000 14.56995 ? 25  ILE A O   1 
ATOM   146  C CB  . ILE A 1 25  ? 43.28588 18.19383  3.14074   1.000 12.86002 ? 25  ILE A CB  1 
ATOM   147  C CG1 . ILE A 1 25  ? 42.79305 16.73409  3.19067   1.000 12.61512 ? 25  ILE A CG1 1 
ATOM   148  C CG2 . ILE A 1 25  ? 44.11057 18.41590  1.88471   1.000 13.16960 ? 25  ILE A CG2 1 
ATOM   149  C CD1 . ILE A 1 25  ? 43.89721 15.69832  3.00574   1.000 15.06899 ? 25  ILE A CD1 1 
ATOM   150  N N   . SER A 1 26  ? 46.11529 19.76605  3.91845   1.000 12.70150 ? 26  SER A N   1 
ATOM   151  C CA  . SER A 1 26  ? 46.90061 20.92824  3.52343   1.000 15.18092 ? 26  SER A CA  1 
ATOM   152  C C   . SER A 1 26  ? 47.36498 20.75104  2.08421   1.000 14.34719 ? 26  SER A C   1 
ATOM   153  O O   . SER A 1 26  ? 47.61199 19.62716  1.63249   1.000 14.86849 ? 26  SER A O   1 
ATOM   154  C CB  . SER A 1 26  ? 48.10582 21.14964  4.46062   1.000 17.18183 ? 26  SER A CB  1 
ATOM   155  O OG  . SER A 1 26  ? 49.07418 20.15014  4.28651   1.000 24.50792 ? 26  SER A OG  1 
ATOM   156  N N   . VAL A 1 27  ? 47.45081 21.86308  1.35093   1.000 14.01770 ? 27  VAL A N   1 
ATOM   157  C CA  . VAL A 1 27  ? 47.83371 21.85581  -0.06143  1.000 13.30132 ? 27  VAL A CA  1 
ATOM   158  C C   . VAL A 1 27  ? 48.98267 22.83578  -0.25709  1.000 14.87502 ? 27  VAL A C   1 
ATOM   159  O O   . VAL A 1 27  ? 48.87911 24.00605  0.13026   1.000 17.39280 ? 27  VAL A O   1 
ATOM   160  C CB  . VAL A 1 27  ? 46.65080 22.22023  -0.97893  1.000 13.68337 ? 27  VAL A CB  1 
ATOM   161  C CG1 . VAL A 1 27  ? 47.12560 22.35691  -2.42288  1.000 15.75914 ? 27  VAL A CG1 1 
ATOM   162  C CG2 . VAL A 1 27  ? 45.54811 21.16596  -0.86442  1.000 15.69752 ? 27  VAL A CG2 1 
ATOM   163  N N   . ALA A 1 28  ? 50.07944 22.35727  -0.84348  1.000 14.11692 ? 28  ALA A N   1 
ATOM   164  C CA  . ALA A 1 28  ? 51.26540 23.18006  -1.05092  1.000 16.59182 ? 28  ALA A CA  1 
ATOM   165  C C   . ALA A 1 28  ? 51.93791 22.75138  -2.34823  1.000 16.34396 ? 28  ALA A C   1 
ATOM   166  O O   . ALA A 1 28  ? 51.49525 21.81961  -3.02432  1.000 16.01845 ? 28  ALA A O   1 
ATOM   167  C CB  . ALA A 1 28  ? 52.22072 23.07404  0.14037   1.000 17.11277 ? 28  ALA A CB  1 
ATOM   168  N N   . GLY A 1 29  ? 53.00999 23.46017  -2.71243  1.000 16.69123 ? 29  GLY A N   1 
ATOM   169  C CA  . GLY A 1 29  ? 53.79952 23.02033  -3.85050  1.000 18.90094 ? 29  GLY A CA  1 
ATOM   170  C C   . GLY A 1 29  ? 54.34472 21.61698  -3.69745  1.000 18.86429 ? 29  GLY A C   1 
ATOM   171  O O   . GLY A 1 29  ? 54.59947 20.94479  -4.70109  1.000 20.57476 ? 29  GLY A O   1 
ATOM   172  N N   . THR A 1 30  ? 54.50849 21.15042  -2.46157  1.000 18.30228 ? 30  THR A N   1 
ATOM   173  C CA  . THR A 1 30  ? 54.96724 19.79410  -2.19419  1.000 18.06397 ? 30  THR A CA  1 
ATOM   174  C C   . THR A 1 30  ? 53.84957 18.76156  -2.29173  1.000 17.58577 ? 30  THR A C   1 
ATOM   175  O O   . THR A 1 30  ? 54.10945 17.56673  -2.12080  1.000 19.17170 ? 30  THR A O   1 
ATOM   176  C CB  . THR A 1 30  ? 55.59714 19.72429  -0.80298  1.000 20.93374 ? 30  THR A CB  1 
ATOM   177  O OG1 . THR A 1 30  ? 54.71334 20.32702  0.14946   1.000 20.62940 ? 30  THR A OG1 1 
ATOM   178  C CG2 . THR A 1 30  ? 56.94078 20.46309  -0.79113  1.000 22.07715 ? 30  THR A CG2 1 
ATOM   179  N N   . GLY A 1 31  ? 52.61384 19.17861  -2.53000  1.000 15.49221 ? 31  GLY A N   1 
ATOM   180  C CA  . GLY A 1 31  ? 51.53757 18.24352  -2.78385  1.000 15.44368 ? 31  GLY A CA  1 
ATOM   181  C C   . GLY A 1 31  ? 50.41776 18.36967  -1.77123  1.000 14.16409 ? 31  GLY A C   1 
ATOM   182  O O   . GLY A 1 31  ? 50.28840 19.36246  -1.04371  1.000 16.58652 ? 31  GLY A O   1 
ATOM   183  N N   . VAL A 1 32  ? 49.59041 17.33277  -1.74191  1.000 13.82453 ? 32  VAL A N   1 
ATOM   184  C CA  . VAL A 1 32  ? 48.45416 17.23517  -0.84074  1.000 12.76392 ? 32  VAL A CA  1 
ATOM   185  C C   . VAL A 1 32  ? 48.90711 16.43174  0.36599   1.000 14.31335 ? 32  VAL A C   1 
ATOM   186  O O   . VAL A 1 32  ? 49.42170 15.31537  0.21545   1.000 14.46188 ? 32  VAL A O   1 
ATOM   187  C CB  . VAL A 1 32  ? 47.28539 16.53153  -1.55278  1.000 13.59551 ? 32  VAL A CB  1 
ATOM   188  C CG1 . VAL A 1 32  ? 46.15803 16.28769  -0.58902  1.000 14.85271 ? 32  VAL A CG1 1 
ATOM   189  C CG2 . VAL A 1 32  ? 46.82947 17.35054  -2.77632  1.000 13.63812 ? 32  VAL A CG2 1 
ATOM   190  N N   . ALA A 1 33  ? 48.72067 16.98600  1.56072   1.000 13.40972 ? 33  ALA A N   1 
ATOM   191  C CA  . ALA A 1 33  ? 49.17065 16.34143  2.78696   1.000 13.38495 ? 33  ALA A CA  1 
ATOM   192  C C   . ALA A 1 33  ? 48.03716 16.30553  3.80933   1.000 13.28315 ? 33  ALA A C   1 
ATOM   193  O O   . ALA A 1 33  ? 47.08495 17.08245  3.73835   1.000 14.28084 ? 33  ALA A O   1 
ATOM   194  C CB  . ALA A 1 33  ? 50.37490 17.07623  3.39257   1.000 13.72824 ? 33  ALA A CB  1 
ATOM   195  N N   . VAL A 1 34  ? 48.14085 15.38845  4.76739   1.000 12.35033 ? 34  VAL A N   1 
ATOM   196  C CA  . VAL A 1 34  ? 47.23152 15.39482  5.90866   1.000 13.21227 ? 34  VAL A CA  1 
ATOM   197  C C   . VAL A 1 34  ? 47.65415 16.49147  6.87396   1.000 13.50874 ? 34  VAL A C   1 
ATOM   198  O O   . VAL A 1 34  ? 48.84831 16.66065  7.16170   1.000 14.38131 ? 34  VAL A O   1 
ATOM   199  C CB  . VAL A 1 34  ? 47.20624 14.02243  6.59548   1.000 12.69831 ? 34  VAL A CB  1 
ATOM   200  C CG1 . VAL A 1 34  ? 46.46815 14.08702  7.94534   1.000 12.47267 ? 34  VAL A CG1 1 
ATOM   201  C CG2 . VAL A 1 34  ? 46.50969 13.02413  5.69094   1.000 16.19846 ? 34  VAL A CG2 1 
ATOM   202  N N   . LYS A 1 35  ? 46.66908 17.25722  7.35234   1.000 13.14040 ? 35  LYS A N   1 
ATOM   203  C CA  . LYS A 1 35  ? 46.85636 18.26509  8.39041   1.000 12.40456 ? 35  LYS A CA  1 
ATOM   204  C C   . LYS A 1 35  ? 46.32322 17.68424  9.69651   1.000 13.41817 ? 35  LYS A C   1 
ATOM   205  O O   . LYS A 1 35  ? 45.11564 17.44319  9.83396   1.000 14.11754 ? 35  LYS A O   1 
ATOM   206  C CB  . LYS A 1 35  ? 46.09333 19.53030  8.01719   1.000 14.89847 ? 35  LYS A CB  1 
ATOM   207  C CG  . LYS A 1 35  ? 46.19119 20.63389  9.05403   1.000 17.07651 ? 35  LYS A CG  1 
ATOM   208  C CD  . LYS A 1 35  ? 45.58041 21.92812  8.51610   1.000 21.37181 ? 35  LYS A CD  1 
ATOM   209  C CE  . LYS A 1 35  ? 45.22954 22.87047  9.64767   1.000 24.89382 ? 35  LYS A CE  1 
ATOM   210  N NZ  . LYS A 1 35  ? 45.60517 24.27385  9.31656   1.000 32.66848 ? 35  LYS A NZ  1 
ATOM   211  N N   . VAL A 1 36  ? 47.21290 17.43098  10.64196  1.000 15.40737 ? 36  VAL A N   1 
ATOM   212  C CA  . VAL A 1 36  ? 46.79657 16.96553  11.95897  1.000 15.79933 ? 36  VAL A CA  1 
ATOM   213  C C   . VAL A 1 36  ? 46.60161 18.17179  12.85717  1.000 15.67420 ? 36  VAL A C   1 
ATOM   214  O O   . VAL A 1 36  ? 47.27340 19.19259  12.70693  1.000 16.88104 ? 36  VAL A O   1 
ATOM   215  C CB  . VAL A 1 36  ? 47.80758 15.97609  12.58140  1.000 15.71775 ? 36  VAL A CB  1 
ATOM   216  C CG1 . VAL A 1 36  ? 47.88253 14.70237  11.75464  1.000 17.22439 ? 36  VAL A CG1 1 
ATOM   217  C CG2 . VAL A 1 36  ? 49.20189 16.62217  12.76694  1.000 18.05967 ? 36  VAL A CG2 1 
ATOM   218  N N   . GLU A 1 37  ? 45.66120 18.06606  13.78950  1.000 14.62104 ? 37  GLU A N   1 
ATOM   219  C CA  . GLU A 1 37  ? 45.62019 19.00251  14.90310  1.000 17.26755 ? 37  GLU A CA  1 
ATOM   220  C C   . GLU A 1 37  ? 46.68760 18.59360  15.90292  1.000 19.39783 ? 37  GLU A C   1 
ATOM   221  O O   . GLU A 1 37  ? 46.52876 17.60369  16.62635  1.000 19.29398 ? 37  GLU A O   1 
ATOM   222  C CB  . GLU A 1 37  ? 44.23547 19.07676  15.53963  1.000 16.64131 ? 37  GLU A CB  1 
ATOM   223  C CG  . GLU A 1 37  ? 44.21938 20.19342  16.58998  1.000 23.56488 ? 37  GLU A CG  1 
ATOM   224  C CD  . GLU A 1 37  ? 42.84981 20.60706  17.07378  1.000 26.92372 ? 37  GLU A CD  1 
ATOM   225  O OE1 . GLU A 1 37  ? 42.79810 21.63952  17.77462  1.000 26.71548 ? 37  GLU A OE1 1 
ATOM   226  O OE2 . GLU A 1 37  ? 41.84002 19.95548  16.72639  1.000 21.75283 ? 37  GLU A OE2 1 
ATOM   227  N N   . ALA A 1 38  ? 47.77699 19.37479  15.93914  1.000 22.66169 ? 38  ALA A N   1 
ATOM   228  C CA  . ALA A 1 38  ? 49.00857 18.95048  16.59911  1.000 24.05891 ? 38  ALA A CA  1 
ATOM   229  C C   . ALA A 1 38  ? 48.81449 18.66556  18.08337  1.000 22.64485 ? 38  ALA A C   1 
ATOM   230  O O   . ALA A 1 38  ? 49.54542 17.85221  18.65002  1.000 23.96785 ? 38  ALA A O   1 
ATOM   231  C CB  . ALA A 1 38  ? 50.09838 20.00499  16.39055  1.000 27.84570 ? 38  ALA A CB  1 
ATOM   232  N N   . SER A 1 39  ? 47.84434 19.31473  18.72505  1.000 19.57212 ? 39  SER A N   1 
ATOM   233  C CA  . SER A 1 39  ? 47.59937 19.15265  20.15444  1.000 19.35480 ? 39  SER A CA  1 
ATOM   234  C C   . SER A 1 39  ? 46.72183 17.95461  20.49833  1.000 18.69825 ? 39  SER A C   1 
ATOM   235  O O   . SER A 1 39  ? 46.53207 17.67464  21.68630  1.000 22.07375 ? 39  SER A O   1 
ATOM   236  C CB  . SER A 1 39  ? 46.91680 20.40575  20.70424  1.000 23.94786 ? 39  SER A CB  1 
ATOM   237  O OG  . SER A 1 39  ? 45.60797 20.51508  20.15942  1.000 25.52722 ? 39  SER A OG  1 
ATOM   238  N N   . LYS A 1 40  ? 46.17858 17.24546  19.50592  1.000 18.08626 ? 40  LYS A N   1 
ATOM   239  C CA  . LYS A 1 40  ? 45.20755 16.17989  19.73650  1.000 15.98187 ? 40  LYS A CA  1 
ATOM   240  C C   . LYS A 1 40  ? 45.77948 14.78799  19.48934  1.000 15.47158 ? 40  LYS A C   1 
ATOM   241  O O   . LYS A 1 40  ? 45.02901 13.83390  19.23280  1.000 14.63347 ? 40  LYS A O   1 
ATOM   242  C CB  . LYS A 1 40  ? 43.92193 16.43377  18.95285  1.000 17.66593 ? 40  LYS A CB  1 
ATOM   243  C CG  . LYS A 1 40  ? 43.30898 17.78827  19.33245  1.000 21.08765 ? 40  LYS A CG  1 
ATOM   244  C CD  . LYS A 1 40  ? 41.80029 17.77667  19.30864  1.000 26.97447 ? 40  LYS A CD  1 
ATOM   245  C CE  . LYS A 1 40  ? 41.25549 19.08245  19.88099  1.000 25.39802 ? 40  LYS A CE  1 
ATOM   246  N NZ  . LYS A 1 40  ? 40.66984 18.86079  21.23083  1.000 32.10637 ? 40  LYS A NZ  1 
ATOM   247  N N   . GLY A 1 41  ? 47.09716 14.65394  19.58952  1.000 16.60003 ? 41  GLY A N   1 
ATOM   248  C CA  . GLY A 1 41  ? 47.72756 13.36314  19.73376  1.000 14.82362 ? 41  GLY A CA  1 
ATOM   249  C C   . GLY A 1 41  ? 48.18400 12.70002  18.45687  1.000 15.63210 ? 41  GLY A C   1 
ATOM   250  O O   . GLY A 1 41  ? 48.72275 11.59243  18.52402  1.000 14.02993 ? 41  GLY A O   1 
ATOM   251  N N   . LEU A 1 42  ? 47.98717 13.31798  17.29589  1.000 14.36758 ? 42  LEU A N   1 
ATOM   252  C CA  . LEU A 1 42  ? 48.41070 12.70448  16.04420  1.000 14.97363 ? 42  LEU A CA  1 
ATOM   253  C C   . LEU A 1 42  ? 49.57700 13.47021  15.43663  1.000 15.64090 ? 42  LEU A C   1 
ATOM   254  O O   . LEU A 1 42  ? 49.74786 14.67336  15.65739  1.000 18.11811 ? 42  LEU A O   1 
ATOM   255  C CB  . LEU A 1 42  ? 47.27440 12.63868  15.01409  1.000 17.10467 ? 42  LEU A CB  1 
ATOM   256  C CG  . LEU A 1 42  ? 45.98286 11.92974  15.43061  1.000 15.79422 ? 42  LEU A CG  1 
ATOM   257  C CD1 . LEU A 1 42  ? 44.99464 11.91501  14.26574  1.000 16.70757 ? 42  LEU A CD1 1 
ATOM   258  C CD2 . LEU A 1 42  ? 46.24422 10.51455  15.91358  1.000 18.24933 ? 42  LEU A CD2 1 
ATOM   259  N N   . GLN A 1 43  ? 50.36083 12.75282  14.64389  1.000 15.00339 ? 43  GLN A N   1 
ATOM   260  C CA  . GLN A 1 43  ? 51.48848 13.30586  13.91680  1.000 15.86280 ? 43  GLN A CA  1 
ATOM   261  C C   . GLN A 1 43  ? 51.37427 12.82898  12.48086  1.000 17.38645 ? 43  GLN A C   1 
ATOM   262  O O   . GLN A 1 43  ? 50.64868 11.87769  12.18616  1.000 16.03970 ? 43  GLN A O   1 
ATOM   263  C CB  . GLN A 1 43  ? 52.81675 12.80057  14.50454  1.000 15.34114 ? 43  GLN A CB  1 
ATOM   264  C CG  . GLN A 1 43  ? 52.90556 11.28373  14.52375  1.000 14.25874 ? 43  GLN A CG  1 
ATOM   265  C CD  . GLN A 1 43  ? 54.27211 10.79331  14.95593  1.000 16.53402 ? 43  GLN A CD  1 
ATOM   266  O OE1 . GLN A 1 43  ? 54.83263 11.28837  15.92506  1.000 17.96660 ? 43  GLN A OE1 1 
ATOM   267  N NE2 . GLN A 1 43  ? 54.81861 9.83414   14.22706  1.000 18.14105 ? 43  GLN A NE2 1 
ATOM   268  N N   . VAL A 1 44  ? 52.08313 13.50992  11.58092  1.000 15.19662 ? 44  VAL A N   1 
ATOM   269  C CA  . VAL A 1 44  ? 52.18699 13.06427  10.19819  1.000 17.05460 ? 44  VAL A CA  1 
ATOM   270  C C   . VAL A 1 44  ? 53.63610 13.22190  9.76714   1.000 17.64241 ? 44  VAL A C   1 
ATOM   271  O O   . VAL A 1 44  ? 54.22136 14.30166  9.91300   1.000 20.60900 ? 44  VAL A O   1 
ATOM   272  C CB  . VAL A 1 44  ? 51.18326 13.76820  9.25102   1.000 18.42512 ? 44  VAL A CB  1 
ATOM   273  C CG1 . VAL A 1 44  ? 51.30282 15.29638  9.30521   1.000 22.64322 ? 44  VAL A CG1 1 
ATOM   274  C CG2 . VAL A 1 44  ? 51.32318 13.21115  7.82524   1.000 19.39608 ? 44  VAL A CG2 1 
ATOM   275  N N   . THR A 1 45  ? 54.22405 12.13809  9.28478   1.000 17.63082 ? 45  THR A N   1 
ATOM   276  C CA  . THR A 1 45  ? 55.59293 12.15062  8.78620   1.000 20.37513 ? 45  THR A CA  1 
ATOM   277  C C   . THR A 1 45  ? 55.59067 11.59466  7.37106   1.000 19.61392 ? 45  THR A C   1 
ATOM   278  O O   . THR A 1 45  ? 54.54664 11.26114  6.81864   1.000 18.20710 ? 45  THR A O   1 
ATOM   279  C CB  . THR A 1 45  ? 56.50946 11.31340  9.68446   1.000 21.34242 ? 45  THR A CB  1 
ATOM   280  O OG1 . THR A 1 45  ? 56.23005 9.92571   9.48850   1.000 21.71821 ? 45  THR A OG1 1 
ATOM   281  C CG2 . THR A 1 45  ? 56.29535 11.66282  11.15109  1.000 24.69872 ? 45  THR A CG2 1 
ATOM   282  N N   . SER A 1 46  ? 56.78260 11.47201  6.77778   1.000 23.65115 ? 46  SER A N   1 
ATOM   283  C CA  . SER A 1 46  ? 56.87802 10.83981  5.46596   1.000 23.98686 ? 46  SER A CA  1 
ATOM   284  C C   . SER A 1 46  ? 56.40657 9.38940   5.48602   1.000 22.63448 ? 46  SER A C   1 
ATOM   285  O O   . SER A 1 46  ? 56.07273 8.84146   4.43144   1.000 25.37159 ? 46  SER A O   1 
ATOM   286  C CB  . SER A 1 46  ? 58.31396 10.91832  4.94404   1.000 28.74178 ? 46  SER A CB  1 
ATOM   287  O OG  . SER A 1 46  ? 59.19288 10.26223  5.83388   1.000 30.34921 ? 46  SER A OG  1 
ATOM   288  N N   . ASN A 1 47  ? 56.35173 8.76188   6.65841   1.000 22.83030 ? 47  ASN A N   1 
ATOM   289  C CA  . ASN A 1 47  ? 55.83237 7.40921   6.79412   1.000 23.92653 ? 47  ASN A CA  1 
ATOM   290  C C   . ASN A 1 47  ? 54.31612 7.35191   6.94812   1.000 21.27546 ? 47  ASN A C   1 
ATOM   291  O O   . ASN A 1 47  ? 53.73761 6.26279   6.85086   1.000 23.19862 ? 47  ASN A O   1 
ATOM   292  C CB  . ASN A 1 47  ? 56.52011 6.71571   7.97080   1.000 24.80742 ? 47  ASN A CB  1 
ATOM   293  C CG  . ASN A 1 47  ? 58.02264 6.62230   7.77223   1.000 29.28311 ? 47  ASN A CG  1 
ATOM   294  O OD1 . ASN A 1 47  ? 58.48619 6.15390   6.73373   1.000 33.49830 ? 47  ASN A OD1 1 
ATOM   295  N ND2 . ASN A 1 47  ? 58.78399 7.11679   8.73819   1.000 31.08678 ? 47  ASN A ND2 1 
ATOM   296  N N   . GLY A 1 48  ? 53.66020 8.48126   7.17080   1.000 18.25647 ? 48  GLY A N   1 
ATOM   297  C CA  . GLY A 1 48  ? 52.21139 8.53132   7.22620   1.000 17.68846 ? 48  GLY A CA  1 
ATOM   298  C C   . GLY A 1 48  ? 51.71181 9.11545   8.53360   1.000 16.74785 ? 48  GLY A C   1 
ATOM   299  O O   . GLY A 1 48  ? 52.47276 9.66961   9.34092   1.000 17.57109 ? 48  GLY A O   1 
ATOM   300  N N   . VAL A 1 49  ? 50.39002 8.99112   8.73549   1.000 17.10672 ? 49  VAL A N   1 
ATOM   301  C CA  . VAL A 1 49  ? 49.71623 9.52320   9.91594   1.000 13.64585 ? 49  VAL A CA  1 
ATOM   302  C C   . VAL A 1 49  ? 49.80479 8.49620   11.03245  1.000 15.19936 ? 49  VAL A C   1 
ATOM   303  O O   . VAL A 1 49  ? 49.73707 7.28778   10.78617  1.000 15.38717 ? 49  VAL A O   1 
ATOM   304  C CB  . VAL A 1 49  ? 48.24914 9.86149   9.58182   1.000 14.26056 ? 49  VAL A CB  1 
ATOM   305  C CG1 . VAL A 1 49  ? 47.61071 10.68178  10.70097  1.000 13.54110 ? 49  VAL A CG1 1 
ATOM   306  C CG2 . VAL A 1 49  ? 48.16165 10.58928  8.24698   1.000 17.44781 ? 49  VAL A CG2 1 
ATOM   307  N N   . GLY A 1 50  ? 49.95285 8.97162   12.26805  1.000 14.44915 ? 50  GLY A N   1 
ATOM   308  C CA  . GLY A 1 50  ? 50.04042 8.05980   13.39558  1.000 15.51920 ? 50  GLY A CA  1 
ATOM   309  C C   . GLY A 1 50  ? 49.83022 8.79933   14.69761  1.000 15.47584 ? 50  GLY A C   1 
ATOM   310  O O   . GLY A 1 50  ? 49.70378 10.02319  14.73589  1.000 15.79453 ? 50  GLY A O   1 
ATOM   311  N N   . LEU A 1 51  ? 49.79317 8.03033   15.77816  1.000 14.27068 ? 51  LEU A N   1 
ATOM   312  C CA  . LEU A 1 51  ? 49.79766 8.62733   17.10726  1.000 13.93520 ? 51  LEU A CA  1 
ATOM   313  C C   . LEU A 1 51  ? 51.18836 9.14456   17.44987  1.000 13.52322 ? 51  LEU A C   1 
ATOM   314  O O   . LEU A 1 51  ? 52.19998 8.52556   17.09618  1.000 14.81108 ? 51  LEU A O   1 
ATOM   315  C CB  . LEU A 1 51  ? 49.42528 7.56380   18.13360  1.000 17.04326 ? 51  LEU A CB  1 
ATOM   316  C CG  . LEU A 1 51  ? 47.98224 7.08138   18.05860  1.000 19.53366 ? 51  LEU A CG  1 
ATOM   317  C CD1 . LEU A 1 51  ? 47.79406 5.73189   18.73590  1.000 21.80679 ? 51  LEU A CD1 1 
ATOM   318  C CD2 . LEU A 1 51  ? 47.09246 8.11842   18.69594  1.000 18.09669 ? 51  LEU A CD2 1 
ATOM   319  N N   . ASN A 1 52  ? 51.24169 10.28311  18.14124  1.000 13.85639 ? 52  ASN A N   1 
ATOM   320  C CA  . ASN A 1 52  ? 52.50903 10.78531  18.64752  1.000 13.89420 ? 52  ASN A CA  1 
ATOM   321  C C   . ASN A 1 52  ? 52.78550 10.20332  20.03785  1.000 15.24180 ? 52  ASN A C   1 
ATOM   322  O O   . ASN A 1 52  ? 51.96824 9.47267   20.60454  1.000 15.56128 ? 52  ASN A O   1 
ATOM   323  C CB  . ASN A 1 52  ? 52.59041 12.31509  18.57681  1.000 14.93947 ? 52  ASN A CB  1 
ATOM   324  C CG  . ASN A 1 52  ? 51.67297 13.01739  19.58147  1.000 16.13578 ? 52  ASN A CG  1 
ATOM   325  O OD1 . ASN A 1 52  ? 51.41605 12.50461  20.67178  1.000 14.86541 ? 52  ASN A OD1 1 
ATOM   326  N ND2 . ASN A 1 52  ? 51.21265 14.21858  19.22818  1.000 17.77495 ? 52  ASN A ND2 1 
ATOM   327  N N   . ASN A 1 53  ? 53.93747 10.55052  20.61452  1.000 14.68011 ? 53  ASN A N   1 
ATOM   328  C CA  . ASN A 1 53  ? 54.39108 9.88736   21.83343  1.000 14.35606 ? 53  ASN A CA  1 
ATOM   329  C C   . ASN A 1 53  ? 53.79711 10.47970  23.10544  1.000 15.75434 ? 53  ASN A C   1 
ATOM   330  O O   . ASN A 1 53  ? 54.11436 9.98853   24.19642  1.000 18.17002 ? 53  ASN A O   1 
ATOM   331  C CB  . ASN A 1 53  ? 55.92515 9.88405   21.89799  1.000 15.22507 ? 53  ASN A CB  1 
ATOM   332  C CG  . ASN A 1 53  ? 56.53203 8.92842   20.90259  1.000 20.21708 ? 53  ASN A CG  1 
ATOM   333  O OD1 . ASN A 1 53  ? 55.87902 7.98950   20.44742  1.000 22.76726 ? 53  ASN A OD1 1 
ATOM   334  N ND2 . ASN A 1 53  ? 57.77610 9.17605   20.53189  1.000 21.47753 ? 53  ASN A ND2 1 
ATOM   335  N N   . THR A 1 54  ? 52.95917 11.51284  23.00236  1.000 16.15387 ? 54  THR A N   1 
ATOM   336  C CA  . THR A 1 54  ? 52.23702 12.04798  24.15043  1.000 15.96100 ? 54  THR A CA  1 
ATOM   337  C C   . THR A 1 54  ? 50.73232 11.82784  24.06177  1.000 16.94454 ? 54  THR A C   1 
ATOM   338  O O   . THR A 1 54  ? 49.99581 12.32140  24.92763  1.000 15.63862 ? 54  THR A O   1 
ATOM   339  C CB  . THR A 1 54  ? 52.56439 13.53365  24.39093  1.000 19.35660 ? 54  THR A CB  1 
ATOM   340  O OG1 . THR A 1 54  ? 52.41539 14.28336  23.18015  1.000 21.43886 ? 54  THR A OG1 1 
ATOM   341  C CG2 . THR A 1 54  ? 53.95185 13.71052  24.93845  1.000 20.62941 ? 54  THR A CG2 1 
ATOM   342  N N   . ALA A 1 55  ? 50.25628 11.09199  23.04472  1.000 13.71097 ? 55  ALA A N   1 
ATOM   343  C CA  . ALA A 1 55  ? 48.82075 10.84966  22.91401  1.000 12.71428 ? 55  ALA A CA  1 
ATOM   344  C C   . ALA A 1 55  ? 48.27330 10.15714  24.14523  1.000 13.52985 ? 55  ALA A C   1 
ATOM   345  O O   . ALA A 1 55  ? 47.13026 10.41044  24.54078  1.000 12.35424 ? 55  ALA A O   1 
ATOM   346  C CB  . ALA A 1 55  ? 48.52485 10.01788  21.66511  1.000 11.66424 ? 55  ALA A CB  1 
ATOM   347  N N   . TRP A 1 56  ? 49.08574 9.30776   24.77805  1.000 12.49478 ? 56  TRP A N   1 
ATOM   348  C CA  . TRP A 1 56  ? 48.64747 8.61683   25.98450  1.000 13.74763 ? 56  TRP A CA  1 
ATOM   349  C C   . TRP A 1 56  ? 48.22807 9.58512   27.08923  1.000 14.09213 ? 56  TRP A C   1 
ATOM   350  O O   . TRP A 1 56  ? 47.32849 9.26742   27.87084  1.000 13.80408 ? 56  TRP A O   1 
ATOM   351  C CB  . TRP A 1 56  ? 49.74860 7.66560   26.45942  1.000 13.92085 ? 56  TRP A CB  1 
ATOM   352  C CG  . TRP A 1 56  ? 50.98622 8.33361   26.98526  1.000 14.90018 ? 56  TRP A CG  1 
ATOM   353  C CD1 . TRP A 1 56  ? 52.13501 8.62600   26.28647  1.000 15.51061 ? 56  TRP A CD1 1 
ATOM   354  C CD2 . TRP A 1 56  ? 51.21584 8.76613   28.32538  1.000 13.97186 ? 56  TRP A CD2 1 
ATOM   355  N NE1 . TRP A 1 56  ? 53.05747 9.21259   27.11847  1.000 15.60977 ? 56  TRP A NE1 1 
ATOM   356  C CE2 . TRP A 1 56  ? 52.51895 9.31037   28.37535  1.000 15.42038 ? 56  TRP A CE2 1 
ATOM   357  C CE3 . TRP A 1 56  ? 50.45022 8.73295   29.49675  1.000 14.35867 ? 56  TRP A CE3 1 
ATOM   358  C CZ2 . TRP A 1 56  ? 53.06793 9.82898   29.54951  1.000 15.04029 ? 56  TRP A CZ2 1 
ATOM   359  C CZ3 . TRP A 1 56  ? 50.99581 9.24703   30.66076  1.000 14.40141 ? 56  TRP A CZ3 1 
ATOM   360  C CH2 . TRP A 1 56  ? 52.29437 9.77493   30.68303  1.000 14.16761 ? 56  TRP A CH2 1 
ATOM   361  N N   . ILE A 1 57  ? 48.85498 10.76222  27.17298  1.000 12.74114 ? 57  ILE A N   1 
ATOM   362  C CA  . ILE A 1 57  ? 48.47609 11.74272  28.19022  1.000 13.56912 ? 57  ILE A CA  1 
ATOM   363  C C   . ILE A 1 57  ? 47.05055 12.22242  27.95662  1.000 13.03956 ? 57  ILE A C   1 
ATOM   364  O O   . ILE A 1 57  ? 46.25287 12.35514  28.89885  1.000 14.24889 ? 57  ILE A O   1 
ATOM   365  C CB  . ILE A 1 57  ? 49.47418 12.91432  28.20393  1.000 13.44055 ? 57  ILE A CB  1 
ATOM   366  C CG1 . ILE A 1 57  ? 50.87292 12.42980  28.59460  1.000 13.28966 ? 57  ILE A CG1 1 
ATOM   367  C CG2 . ILE A 1 57  ? 48.98028 14.01256  29.13141  1.000 15.07206 ? 57  ILE A CG2 1 
ATOM   368  C CD1 . ILE A 1 57  ? 51.94439 13.51623  28.52965  1.000 15.58964 ? 57  ILE A CD1 1 
ATOM   369  N N   . LYS A 1 58  ? 46.71368 12.51707  26.70004  1.000 12.86098 ? 58  LYS A N   1 
ATOM   370  C CA  . LYS A 1 58  ? 45.33997 12.89137  26.37884  1.000 14.76546 ? 58  LYS A CA  1 
ATOM   371  C C   . LYS A 1 58  ? 44.36913 11.78557  26.76581  1.000 14.80750 ? 58  LYS A C   1 
ATOM   372  O O   . LYS A 1 58  ? 43.27795 12.05509  27.29509  1.000 16.70330 ? 58  LYS A O   1 
ATOM   373  C CB  . LYS A 1 58  ? 45.21414 13.22930  24.88643  1.000 14.15003 ? 58  LYS A CB  1 
ATOM   374  C CG  . LYS A 1 58  ? 43.81528 13.66601  24.48061  1.000 18.33560 ? 58  LYS A CG  1 
ATOM   375  C CD  . LYS A 1 58  ? 43.77006 14.05692  23.01684  1.000 19.70123 ? 58  LYS A CD  1 
ATOM   376  C CE  . LYS A 1 58  ? 42.33265 14.27492  22.56955  1.000 23.20199 ? 58  LYS A CE  1 
ATOM   377  N NZ  . LYS A 1 58  ? 41.74640 15.42884  23.29504  1.000 24.69430 ? 58  LYS A NZ  1 
ATOM   378  N N   . MET A 1 59  ? 44.73876 10.53100  26.50106  1.000 13.22948 ? 59  MET A N   1 
ATOM   379  C CA  . MET A 1 59  ? 43.86012 9.41367   26.83627  1.000 13.31670 ? 59  MET A CA  1 
ATOM   380  C C   . MET A 1 59  ? 43.63307 9.33859   28.33992  1.000 15.45700 ? 59  MET A C   1 
ATOM   381  O O   . MET A 1 59  ? 42.50632 9.09694   28.79928  1.000 13.16195 ? 59  MET A O   1 
ATOM   382  C CB  . MET A 1 59  ? 44.49884 8.11667   26.34073  1.000 14.06689 ? 59  MET A CB  1 
ATOM   383  C CG  . MET A 1 59  ? 44.64623 8.07724   24.83444  1.000 19.52998 ? 59  MET A CG  1 
ATOM   384  S SD  . MET A 1 59  ? 43.09426 8.15003   23.94000  0.593 19.07497 ? 59  MET A SD  1 
ATOM   385  C CE  . MET A 1 59  ? 43.07586 9.87759   23.45455  1.000 25.53204 ? 59  MET A CE  1 
ATOM   386  N N   . MET A 1 60  ? 44.68779 9.56095   29.12573  1.000 13.78928 ? 60  MET A N   1 
ATOM   387  C CA  . MET A 1 60  ? 44.56174 9.37427   30.56477  1.000 13.24269 ? 60  MET A CA  1 
ATOM   388  C C   . MET A 1 60  ? 43.78701 10.52092  31.20340  1.000 13.41065 ? 60  MET A C   1 
ATOM   389  O O   . MET A 1 60  ? 43.03007 10.30278  32.15877  1.000 14.65888 ? 60  MET A O   1 
ATOM   390  C CB  . MET A 1 60  ? 45.93779 9.21027   31.20711  1.000 14.05718 ? 60  MET A CB  1 
ATOM   391  C CG  . MET A 1 60  ? 46.59645 7.96953   30.65115  1.000 15.59220 ? 60  MET A CG  1 
ATOM   392  S SD  . MET A 1 60  ? 45.86954 6.41078   31.18390  0.846 14.85653 ? 60  MET A SD  1 
ATOM   393  C CE  . MET A 1 60  ? 45.91143 6.51824   32.95559  1.000 16.75241 ? 60  MET A CE  1 
ATOM   394  N N   . CYS A 1 61  ? 43.96891 11.74789  30.69848  1.000 14.25211 ? 61  CYS A N   1 
ATOM   395  C CA  . CYS A 1 61  ? 43.14646 12.86030  31.16397  1.000 14.29400 ? 61  CYS A CA  1 
ATOM   396  C C   . CYS A 1 61  ? 41.67801 12.59779  30.86345  1.000 14.31139 ? 61  CYS A C   1 
ATOM   397  O O   . CYS A 1 61  ? 40.79703 12.90854  31.67894  1.000 16.11372 ? 61  CYS A O   1 
ATOM   398  C CB  . CYS A 1 61  ? 43.60422 14.16371  30.50508  1.000 16.33680 ? 61  CYS A CB  1 
ATOM   399  S SG  . CYS A 1 61  ? 45.20345 14.75906  31.11206  0.985 15.59906 ? 61  CYS A SG  1 
ATOM   400  N N   . GLY A 1 62  ? 41.39521 12.01985  29.69517  1.000 15.21208 ? 62  GLY A N   1 
ATOM   401  C CA  . GLY A 1 62  ? 40.02600 11.64915  29.37541  1.000 15.08846 ? 62  GLY A CA  1 
ATOM   402  C C   . GLY A 1 62  ? 39.49401 10.56533  30.29391  1.000 15.57128 ? 62  GLY A C   1 
ATOM   403  O O   . GLY A 1 62  ? 38.37484 10.66836  30.80893  1.000 16.84318 ? 62  GLY A O   1 
ATOM   404  N N   . LEU A 1 63  ? 40.29786 9.52216   30.53051  1.000 14.81563 ? 63  LEU A N   1 
ATOM   405  C CA  . LEU A 1 63  ? 39.87469 8.42294   31.40102  1.000 15.14857 ? 63  LEU A CA  1 
ATOM   406  C C   . LEU A 1 63  ? 39.37158 8.93258   32.74683  1.000 15.31520 ? 63  LEU A C   1 
ATOM   407  O O   . LEU A 1 63  ? 38.31070 8.51748   33.22129  1.000 15.46344 ? 63  LEU A O   1 
ATOM   408  C CB  . LEU A 1 63  ? 41.03548 7.45521   31.61804  1.000 14.60754 ? 63  LEU A CB  1 
ATOM   409  C CG  . LEU A 1 63  ? 40.84163 6.34721   32.66418  1.000 16.03090 ? 63  LEU A CG  1 
ATOM   410  C CD1 . LEU A 1 63  ? 39.69513 5.41072   32.29191  1.000 16.37918 ? 63  LEU A CD1 1 
ATOM   411  C CD2 . LEU A 1 63  ? 42.12023 5.56494   32.83120  1.000 16.30458 ? 63  LEU A CD2 1 
ATOM   412  N N   . HIS A 1 64  ? 40.11203 9.83901   33.37527  1.000 13.50968 ? 64  HIS A N   1 
ATOM   413  C CA  . HIS A 1 64  ? 39.74700 10.33702  34.69918  1.000 13.83953 ? 64  HIS A CA  1 
ATOM   414  C C   . HIS A 1 64  ? 38.98363 11.66053  34.68162  1.000 13.79377 ? 64  HIS A C   1 
ATOM   415  O O   . HIS A 1 64  ? 38.61766 12.16066  35.75229  1.000 16.36559 ? 64  HIS A O   1 
ATOM   416  C CB  . HIS A 1 64  ? 40.99547 10.42625  35.58578  1.000 13.51687 ? 64  HIS A CB  1 
ATOM   417  C CG  . HIS A 1 64  ? 41.59589 9.09232   35.88025  1.000 14.41874 ? 64  HIS A CG  1 
ATOM   418  N ND1 . HIS A 1 64  ? 40.91600 8.11656   36.57773  1.000 14.46625 ? 64  HIS A ND1 1 
ATOM   419  C CD2 . HIS A 1 64  ? 42.78522 8.54710   35.53316  1.000 14.64285 ? 64  HIS A CD2 1 
ATOM   420  C CE1 . HIS A 1 64  ? 41.66907 7.03675   36.66954  1.000 15.29076 ? 64  HIS A CE1 1 
ATOM   421  N NE2 . HIS A 1 64  ? 42.80808 7.26984   36.03577  1.000 14.97511 ? 64  HIS A NE2 1 
ATOM   422  N N   . ASN A 1 65  ? 38.69689 12.21206  33.50728  1.000 14.08670 ? 65  ASN A N   1 
ATOM   423  C CA  . ASN A 1 65  ? 38.11680 13.55133  33.38827  1.000 15.84129 ? 65  ASN A CA  1 
ATOM   424  C C   . ASN A 1 65  ? 38.94370 14.58233  34.14763  1.000 16.23768 ? 65  ASN A C   1 
ATOM   425  O O   . ASN A 1 65  ? 38.41705 15.43070  34.87659  1.000 17.14541 ? 65  ASN A O   1 
ATOM   426  C CB  . ASN A 1 65  ? 36.63737 13.61669  33.79463  1.000 18.20637 ? 65  ASN A CB  1 
ATOM   427  C CG  . ASN A 1 65  ? 35.93415 14.80857  33.17110  1.000 17.88755 ? 65  ASN A CG  1 
ATOM   428  O OD1 . ASN A 1 65  ? 36.34607 15.30461  32.11951  1.000 25.92232 ? 65  ASN A OD1 1 
ATOM   429  N ND2 . ASN A 1 65  ? 34.88602 15.29942  33.83281  1.000 26.47689 ? 65  ASN A ND2 1 
ATOM   430  N N   . ALA A 1 66  ? 40.25779 14.50985  33.95918  1.000 14.86792 ? 66  ALA A N   1 
ATOM   431  C CA  . ALA A 1 66  ? 41.19680 15.38756  34.63652  1.000 13.97281 ? 66  ALA A CA  1 
ATOM   432  C C   . ALA A 1 66  ? 41.46420 16.62231  33.78449  1.000 15.84014 ? 66  ALA A C   1 
ATOM   433  O O   . ALA A 1 66  ? 41.46387 16.55702  32.54998  1.000 17.20124 ? 66  ALA A O   1 
ATOM   434  C CB  . ALA A 1 66  ? 42.51406 14.64207  34.86692  1.000 14.64027 ? 66  ALA A CB  1 
ATOM   435  N N   . THR A 1 67  ? 41.68519 17.75549  34.45575  1.000 14.10906 ? 67  THR A N   1 
ATOM   436  C CA  . THR A 1 67  ? 41.96907 19.00671  33.77021  1.000 15.34833 ? 67  THR A CA  1 
ATOM   437  C C   . THR A 1 67  ? 43.41742 19.45320  33.88663  1.000 14.47546 ? 67  THR A C   1 
ATOM   438  O O   . THR A 1 67  ? 43.80250 20.40538  33.20108  1.000 14.46873 ? 67  THR A O   1 
ATOM   439  C CB  . THR A 1 67  ? 41.03757 20.13761  34.24721  1.000 16.17341 ? 67  THR A CB  1 
ATOM   440  O OG1 . THR A 1 67  ? 41.03172 20.19839  35.67597  1.000 16.88841 ? 67  THR A OG1 1 
ATOM   441  C CG2 . THR A 1 67  ? 39.62068 19.93509  33.74462  1.000 18.16372 ? 67  THR A CG2 1 
ATOM   442  N N   . PHE A 1 68  ? 44.21760 18.80867  34.73057  1.000 13.16773 ? 68  PHE A N   1 
ATOM   443  C CA  . PHE A 1 68  ? 45.65288 19.06263  34.80579  1.000 12.34204 ? 68  PHE A CA  1 
ATOM   444  C C   . PHE A 1 68  ? 46.36473 17.75368  35.06826  1.000 13.92408 ? 68  PHE A C   1 
ATOM   445  O O   . PHE A 1 68  ? 45.76448 16.78475  35.53569  1.000 13.32437 ? 68  PHE A O   1 
ATOM   446  C CB  . PHE A 1 68  ? 46.00760 20.04850  35.92840  1.000 13.71109 ? 68  PHE A CB  1 
ATOM   447  C CG  . PHE A 1 68  ? 45.32903 21.35844  35.77269  1.000 15.56937 ? 68  PHE A CG  1 
ATOM   448  C CD1 . PHE A 1 68  ? 45.90838 22.33547  34.99502  1.000 15.38949 ? 68  PHE A CD1 1 
ATOM   449  C CD2 . PHE A 1 68  ? 44.09111 21.58956  36.34396  1.000 15.40160 ? 68  PHE A CD2 1 
ATOM   450  C CE1 . PHE A 1 68  ? 45.27461 23.54774  34.80150  1.000 15.49050 ? 68  PHE A CE1 1 
ATOM   451  C CE2 . PHE A 1 68  ? 43.44903 22.79486  36.16540  1.000 17.74200 ? 68  PHE A CE2 1 
ATOM   452  C CZ  . PHE A 1 68  ? 44.03811 23.77752  35.38022  1.000 16.85454 ? 68  PHE A CZ  1 
ATOM   453  N N   . TYR A 1 69  ? 47.65631 17.72563  34.74996  1.000 12.84270 ? 69  TYR A N   1 
ATOM   454  C CA  . TYR A 1 69  ? 48.45872 16.53652  34.98138  1.000 12.42932 ? 69  TYR A CA  1 
ATOM   455  C C   . TYR A 1 69  ? 49.90435 16.92730  35.24554  1.000 13.13310 ? 69  TYR A C   1 
ATOM   456  O O   . TYR A 1 69  ? 50.33431 18.05436  34.96357  1.000 14.21784 ? 69  TYR A O   1 
ATOM   457  C CB  . TYR A 1 69  ? 48.39806 15.56232  33.79243  1.000 14.41225 ? 69  TYR A CB  1 
ATOM   458  C CG  . TYR A 1 69  ? 49.21189 16.03396  32.60927  1.000 13.54312 ? 69  TYR A CG  1 
ATOM   459  C CD1 . TYR A 1 69  ? 48.68415 16.93735  31.69078  1.000 13.63429 ? 69  TYR A CD1 1 
ATOM   460  C CD2 . TYR A 1 69  ? 50.51529 15.57992  32.41488  1.000 12.77780 ? 69  TYR A CD2 1 
ATOM   461  C CE1 . TYR A 1 69  ? 49.44430 17.36911  30.60211  1.000 13.65962 ? 69  TYR A CE1 1 
ATOM   462  C CE2 . TYR A 1 69  ? 51.27805 16.00820  31.34272  1.000 13.94747 ? 69  TYR A CE2 1 
ATOM   463  C CZ  . TYR A 1 69  ? 50.73403 16.89888  30.43916  1.000 14.35144 ? 69  TYR A CZ  1 
ATOM   464  O OH  . TYR A 1 69  ? 51.49439 17.32688  29.36798  1.000 15.43046 ? 69  TYR A OH  1 
ATOM   465  N N   . VAL A 1 70  ? 50.66052 15.96223  35.76806  1.000 13.00717 ? 70  VAL A N   1 
ATOM   466  C CA  . VAL A 1 70  ? 52.12072 16.00034  35.72181  1.000 13.32136 ? 70  VAL A CA  1 
ATOM   467  C C   . VAL A 1 70  ? 52.62620 14.69002  35.13807  1.000 12.22839 ? 70  VAL A C   1 
ATOM   468  O O   . VAL A 1 70  ? 51.97637 13.64645  35.23813  1.000 14.03003 ? 70  VAL A O   1 
ATOM   469  C CB  . VAL A 1 70  ? 52.81889 16.25170  37.07758  1.000 14.65433 ? 70  VAL A CB  1 
ATOM   470  C CG1 . VAL A 1 70  ? 52.41964 17.58102  37.68672  1.000 16.33413 ? 70  VAL A CG1 1 
ATOM   471  C CG2 . VAL A 1 70  ? 52.54452 15.11726  38.03152  1.000 15.38356 ? 70  VAL A CG2 1 
ATOM   472  N N   . SER A 1 71  ? 53.81699 14.74586  34.54476  1.000 12.82038 ? 71  SER A N   1 
ATOM   473  C CA  . SER A 1 71  ? 54.49176 13.53893  34.08789  1.000 12.03071 ? 71  SER A CA  1 
ATOM   474  C C   . SER A 1 71  ? 55.98992 13.76866  34.11272  1.000 14.08620 ? 71  SER A C   1 
ATOM   475  O O   . SER A 1 71  ? 56.48065 14.80734  33.65122  1.000 16.52833 ? 71  SER A O   1 
ATOM   476  C CB  . SER A 1 71  ? 54.05215 13.14092  32.67162  1.000 15.21357 ? 71  SER A CB  1 
ATOM   477  O OG  . SER A 1 71  ? 54.56547 11.86989  32.29113  1.000 17.33923 ? 71  SER A OG  1 
ATOM   478  N N   . ASP A 1 72  ? 56.69562 12.80002  34.67787  1.000 13.55703 ? 72  ASP A N   1 
ATOM   479  C CA  . ASP A 1 72  ? 58.14776 12.71749  34.55783  1.000 14.37442 ? 72  ASP A CA  1 
ATOM   480  C C   . ASP A 1 72  ? 58.49734 11.24519  34.34288  1.000 14.31713 ? 72  ASP A C   1 
ATOM   481  O O   . ASP A 1 72  ? 57.61826 10.40685  34.12103  1.000 14.45086 ? 72  ASP A O   1 
ATOM   482  C CB  . ASP A 1 72  ? 58.86159 13.45279  35.70621  1.000 14.98430 ? 72  ASP A CB  1 
ATOM   483  C CG  . ASP A 1 72  ? 58.68203 12.78185  37.05367  1.000 14.24466 ? 72  ASP A CG  1 
ATOM   484  O OD1 . ASP A 1 72  ? 58.28073 11.60179  37.10348  1.000 14.92258 ? 72  ASP A OD1 1 
ATOM   485  O OD2 . ASP A 1 72  ? 58.94842 13.45362  38.08510  1.000 16.35762 ? 72  ASP A OD2 1 
ATOM   486  N N   . THR A 1 73  ? 59.78363 10.90932  34.39123  1.000 15.03630 ? 73  THR A N   1 
ATOM   487  C CA  . THR A 1 73  ? 60.14990 9.51998   34.12997  1.000 15.52765 ? 73  THR A CA  1 
ATOM   488  C C   . THR A 1 73  ? 59.87313 8.57657   35.30108  1.000 14.35106 ? 73  THR A C   1 
ATOM   489  O O   . THR A 1 73  ? 60.14861 7.37730   35.17844  1.000 15.05998 ? 73  THR A O   1 
ATOM   490  C CB  . THR A 1 73  ? 61.61405 9.40348   33.68100  1.000 16.81643 ? 73  THR A CB  1 
ATOM   491  O OG1 . THR A 1 73  ? 62.47286 9.99342   34.65762  1.000 18.47943 ? 73  THR A OG1 1 
ATOM   492  C CG2 . THR A 1 73  ? 61.82623 10.10076  32.33859  1.000 18.62818 ? 73  THR A CG2 1 
ATOM   493  N N   . TYR A 1 74  ? 59.34015 9.07961   36.41821  1.000 14.44586 ? 74  TYR A N   1 
ATOM   494  C CA  . TYR A 1 74  ? 59.04899 8.27355   37.59959  1.000 13.61031 ? 74  TYR A CA  1 
ATOM   495  C C   . TYR A 1 74  ? 57.56491 8.16048   37.91305  1.000 12.82867 ? 74  TYR A C   1 
ATOM   496  O O   . TYR A 1 74  ? 57.15953 7.19734   38.56675  1.000 13.44351 ? 74  TYR A O   1 
ATOM   497  C CB  . TYR A 1 74  ? 59.75617 8.86595   38.83016  1.000 15.22799 ? 74  TYR A CB  1 
ATOM   498  C CG  . TYR A 1 74  ? 61.24131 9.04048   38.63996  1.000 15.43809 ? 74  TYR A CG  1 
ATOM   499  C CD1 . TYR A 1 74  ? 61.74384 10.18190  38.02260  1.000 15.47420 ? 74  TYR A CD1 1 
ATOM   500  C CD2 . TYR A 1 74  ? 62.13711 8.06669   39.06893  1.000 15.52014 ? 74  TYR A CD2 1 
ATOM   501  C CE1 . TYR A 1 74  ? 63.10487 10.34673  37.82404  1.000 16.18698 ? 74  TYR A CE1 1 
ATOM   502  C CE2 . TYR A 1 74  ? 63.50955 8.23217   38.89291  1.000 17.19622 ? 74  TYR A CE2 1 
ATOM   503  C CZ  . TYR A 1 74  ? 63.97647 9.36618   38.27170  1.000 16.55278 ? 74  TYR A CZ  1 
ATOM   504  O OH  . TYR A 1 74  ? 65.33129 9.52787   38.08846  1.000 18.96087 ? 74  TYR A OH  1 
ATOM   505  N N   . VAL A 1 75  ? 56.73756 9.11863   37.49355  1.000 13.42757 ? 75  VAL A N   1 
ATOM   506  C CA  . VAL A 1 75  ? 55.33641 9.12409   37.89850  1.000 14.06132 ? 75  VAL A CA  1 
ATOM   507  C C   . VAL A 1 75  ? 54.55579 9.99632   36.93202  1.000 14.51047 ? 75  VAL A C   1 
ATOM   508  O O   . VAL A 1 75  ? 55.10688 10.89740  36.30040  1.000 13.74637 ? 75  VAL A O   1 
ATOM   509  C CB  . VAL A 1 75  ? 55.18918 9.66452   39.34163  1.000 14.31580 ? 75  VAL A CB  1 
ATOM   510  C CG1 . VAL A 1 75  ? 55.44766 11.18104  39.38171  1.000 15.42876 ? 75  VAL A CG1 1 
ATOM   511  C CG2 . VAL A 1 75  ? 53.83309 9.29364   39.91821  1.000 15.05216 ? 75  VAL A CG2 1 
ATOM   512  N N   . CYS A 1 76  ? 53.25629 9.73577   36.82438  1.000 14.04535 ? 76  CYS A N   1 
ATOM   513  C CA  . CYS A 1 76  ? 52.32285 10.69524  36.25054  1.000 12.75627 ? 76  CYS A CA  1 
ATOM   514  C C   . CYS A 1 76  ? 51.06792 10.74198  37.11080  1.000 12.94412 ? 76  CYS A C   1 
ATOM   515  O O   . CYS A 1 76  ? 50.69567 9.75971   37.76482  1.000 12.96224 ? 76  CYS A O   1 
ATOM   516  C CB  . CYS A 1 76  ? 51.98939 10.42163  34.77503  1.000 15.55312 ? 76  CYS A CB  1 
ATOM   517  S SG  . CYS A 1 76  ? 51.32131 8.79289   34.42654  1.000 14.15044 ? 76  CYS A SG  1 
ATOM   518  N N   . VAL A 1 77  ? 50.43253 11.90878  37.13027  1.000 13.19196 ? 77  VAL A N   1 
ATOM   519  C CA  . VAL A 1 77  ? 49.33092 12.17110  38.04828  1.000 14.18607 ? 77  VAL A CA  1 
ATOM   520  C C   . VAL A 1 77  ? 48.29706 12.99687  37.30276  1.000 13.41727 ? 77  VAL A C   1 
ATOM   521  O O   . VAL A 1 77  ? 48.64846 13.95488  36.61343  1.000 13.71764 ? 77  VAL A O   1 
ATOM   522  C CB  . VAL A 1 77  ? 49.83051 12.91459  39.30742  1.000 12.72676 ? 77  VAL A CB  1 
ATOM   523  C CG1 . VAL A 1 77  ? 48.71645 13.10277  40.30101  1.000 13.75603 ? 77  VAL A CG1 1 
ATOM   524  C CG2 . VAL A 1 77  ? 51.00403 12.18598  39.97110  1.000 14.78489 ? 77  VAL A CG2 1 
ATOM   525  N N   . PHE A 1 78  ? 47.02023 12.64720  37.46165  1.000 12.45281 ? 78  PHE A N   1 
ATOM   526  C CA  . PHE A 1 78  ? 45.91862 13.28364  36.73915  1.000 12.81660 ? 78  PHE A CA  1 
ATOM   527  C C   . PHE A 1 78  ? 44.96080 13.89073  37.74448  1.000 13.67989 ? 78  PHE A C   1 
ATOM   528  O O   . PHE A 1 78  ? 44.34526 13.16027  38.52709  1.000 14.39564 ? 78  PHE A O   1 
ATOM   529  C CB  . PHE A 1 78  ? 45.25223 12.25957  35.82321  1.000 12.34393 ? 78  PHE A CB  1 
ATOM   530  C CG  . PHE A 1 78  ? 46.23632 11.68457  34.86636  1.000 12.19424 ? 78  PHE A CG  1 
ATOM   531  C CD1 . PHE A 1 78  ? 46.58845 12.39893  33.73713  1.000 14.23299 ? 78  PHE A CD1 1 
ATOM   532  C CD2 . PHE A 1 78  ? 46.90785 10.50971  35.15503  1.000 14.94079 ? 78  PHE A CD2 1 
ATOM   533  C CE1 . PHE A 1 78  ? 47.56817 11.93229  32.87918  1.000 13.66908 ? 78  PHE A CE1 1 
ATOM   534  C CE2 . PHE A 1 78  ? 47.88867 10.03729  34.29663  1.000 14.05864 ? 78  PHE A CE2 1 
ATOM   535  C CZ  . PHE A 1 78  ? 48.20654 10.75908  33.14975  1.000 14.61670 ? 78  PHE A CZ  1 
ATOM   536  N N   . PHE A 1 79  ? 44.84479 15.22407  37.71492  1.000 12.67486 ? 79  PHE A N   1 
ATOM   537  C CA  . PHE A 1 79  ? 44.18873 15.99026  38.76994  1.000 14.16360 ? 79  PHE A CA  1 
ATOM   538  C C   . PHE A 1 79  ? 42.77018 16.38406  38.37711  1.000 13.67286 ? 79  PHE A C   1 
ATOM   539  O O   . PHE A 1 79  ? 42.52676 16.88418  37.26878  1.000 13.10392 ? 79  PHE A O   1 
ATOM   540  C CB  . PHE A 1 79  ? 44.96089 17.28137  39.05706  1.000 13.55362 ? 79  PHE A CB  1 
ATOM   541  C CG  . PHE A 1 79  ? 46.35611 17.07503  39.57078  1.000 12.81372 ? 79  PHE A CG  1 
ATOM   542  C CD1 . PHE A 1 79  ? 47.41494 16.88376  38.69472  1.000 13.10715 ? 79  PHE A CD1 1 
ATOM   543  C CD2 . PHE A 1 79  ? 46.61349 17.10304  40.93711  1.000 14.87321 ? 79  PHE A CD2 1 
ATOM   544  C CE1 . PHE A 1 79  ? 48.71778 16.70198  39.17531  1.000 13.55056 ? 79  PHE A CE1 1 
ATOM   545  C CE2 . PHE A 1 79  ? 47.90043 16.91078  41.41433  1.000 13.03973 ? 79  PHE A CE2 1 
ATOM   546  C CZ  . PHE A 1 79  ? 48.95695 16.71919  40.53209  1.000 14.26362 ? 79  PHE A CZ  1 
ATOM   547  N N   . CYS A 1 80  ? 41.84686 16.21305  39.32442  1.000 13.05949 ? 80  CYS A N   1 
ATOM   548  C CA  . CYS A 1 80  ? 40.45613 16.62605  39.17633  1.000 12.73441 ? 80  CYS A CA  1 
ATOM   549  C C   . CYS A 1 80  ? 40.10678 17.58406  40.30450  1.000 13.77497 ? 80  CYS A C   1 
ATOM   550  O O   . CYS A 1 80  ? 40.20920 17.22791  41.48350  1.000 16.47786 ? 80  CYS A O   1 
ATOM   551  C CB  . CYS A 1 80  ? 39.52447 15.41857  39.24975  1.000 13.34580 ? 80  CYS A CB  1 
ATOM   552  S SG  . CYS A 1 80  ? 39.83383 14.15894  38.00499  0.919 14.93094 ? 80  CYS A SG  1 
ATOM   553  N N   . ASN A 1 81  ? 39.66519 18.78472  39.94543  1.000 15.02854 ? 81  ASN A N   1 
ATOM   554  C CA  . ASN A 1 81  ? 39.18389 19.73825  40.93359  1.000 16.62766 ? 81  ASN A CA  1 
ATOM   555  C C   . ASN A 1 81  ? 37.72121 19.45011  41.25097  1.000 14.47180 ? 81  ASN A C   1 
ATOM   556  O O   . ASN A 1 81  ? 36.90720 19.26097  40.34660  1.000 15.71533 ? 81  ASN A O   1 
ATOM   557  C CB  . ASN A 1 81  ? 39.31949 21.14957  40.36811  1.000 17.32046 ? 81  ASN A CB  1 
ATOM   558  C CG  . ASN A 1 81  ? 40.74444 21.63941  40.38707  1.000 17.19391 ? 81  ASN A CG  1 
ATOM   559  O OD1 . ASN A 1 81  ? 41.50279 21.33303  41.29775  1.000 16.00937 ? 81  ASN A OD1 1 
ATOM   560  N ND2 . ASN A 1 81  ? 41.10633 22.43452  39.39364  1.000 17.68155 ? 81  ASN A ND2 1 
ATOM   561  N N   . HIS A 1 82  ? 37.39851 19.39459  42.53683  1.000 16.07472 ? 82  HIS A N   1 
ATOM   562  C CA  . HIS A 1 82  ? 36.02832 19.14217  42.96358  1.000 15.96254 ? 82  HIS A CA  1 
ATOM   563  C C   . HIS A 1 82  ? 35.89066 19.62073  44.39656  1.000 15.30370 ? 82  HIS A C   1 
ATOM   564  O O   . HIS A 1 82  ? 36.87523 19.73398  45.13083  1.000 15.60654 ? 82  HIS A O   1 
ATOM   565  C CB  . HIS A 1 82  ? 35.64364 17.66138  42.82304  1.000 17.01063 ? 82  HIS A CB  1 
ATOM   566  C CG  . HIS A 1 82  ? 36.38715 16.74906  43.74563  1.000 16.00535 ? 82  HIS A CG  1 
ATOM   567  N ND1 . HIS A 1 82  ? 35.82075 16.20305  44.87836  1.000 17.28945 ? 82  HIS A ND1 1 
ATOM   568  C CD2 . HIS A 1 82  ? 37.66362 16.29448  43.70862  1.000 15.98230 ? 82  HIS A CD2 1 
ATOM   569  C CE1 . HIS A 1 82  ? 36.70711 15.43126  45.48370  1.000 17.16068 ? 82  HIS A CE1 1 
ATOM   570  N NE2 . HIS A 1 82  ? 37.83982 15.48142  44.80207  1.000 18.09785 ? 82  HIS A NE2 1 
ATOM   571  N N   . SER A 1 83  ? 34.64947 19.92166  44.78247  1.000 17.13081 ? 83  SER A N   1 
ATOM   572  C CA  . SER A 1 83  ? 34.38486 20.46325  46.11304  1.000 16.68889 ? 83  SER A CA  1 
ATOM   573  C C   . SER A 1 83  ? 35.35241 21.62430  46.34650  1.000 16.29102 ? 83  SER A C   1 
ATOM   574  O O   . SER A 1 83  ? 35.56607 22.43304  45.43236  1.000 18.66621 ? 83  SER A O   1 
ATOM   575  C CB  . SER A 1 83  ? 34.45180 19.32807  47.12317  1.000 18.36590 ? 83  SER A CB  1 
ATOM   576  O OG  . SER A 1 83  ? 34.21757 19.80502  48.43529  1.000 18.94688 ? 83  SER A OG  1 
ATOM   577  N N   . THR A 1 84  ? 36.00896 21.70006  47.49713  1.000 16.97598 ? 84  THR A N   1 
ATOM   578  C CA  . THR A 1 84  ? 36.90004 22.79787  47.84004  1.000 16.00919 ? 84  THR A CA  1 
ATOM   579  C C   . THR A 1 84  ? 38.35098 22.52577  47.46028  1.000 17.95415 ? 84  THR A C   1 
ATOM   580  O O   . THR A 1 84  ? 39.21684 23.36535  47.72833  1.000 18.32202 ? 84  THR A O   1 
ATOM   581  C CB  . THR A 1 84  ? 36.83623 23.06455  49.34675  1.000 19.08408 ? 84  THR A CB  1 
ATOM   582  O OG1 . THR A 1 84  ? 36.96317 21.82644  50.05839  1.000 20.25213 ? 84  THR A OG1 1 
ATOM   583  C CG2 . THR A 1 84  ? 35.50751 23.72066  49.70983  1.000 18.03551 ? 84  THR A CG2 1 
ATOM   584  N N   . GLY A 1 85  ? 38.64902 21.37668  46.86151  1.000 16.42388 ? 85  GLY A N   1 
ATOM   585  C CA  . GLY A 1 85  ? 40.03013 20.95961  46.64998  1.000 17.09827 ? 85  GLY A CA  1 
ATOM   586  C C   . GLY A 1 85  ? 40.21887 20.17741  45.38480  1.000 13.98085 ? 85  GLY A C   1 
ATOM   587  O O   . GLY A 1 85  ? 39.64180 20.50201  44.33724  1.000 16.10268 ? 85  GLY A O   1 
ATOM   588  N N   . CYS A 1 86  ? 41.01281 19.11342  45.48134  1.000 15.54824 ? 86  CYS A N   1 
ATOM   589  C CA  . CYS A 1 86  ? 41.50146 18.39718  44.31793  1.000 16.93003 ? 86  CYS A CA  1 
ATOM   590  C C   . CYS A 1 86  ? 41.75219 16.95238  44.72570  1.000 15.11991 ? 86  CYS A C   1 
ATOM   591  O O   . CYS A 1 86  ? 42.21091 16.69107  45.84061  1.000 17.16879 ? 86  CYS A O   1 
ATOM   592  C CB  . CYS A 1 86  ? 42.81648 19.06738  43.88622  1.000 24.26707 ? 86  CYS A CB  1 
ATOM   593  S SG  . CYS A 1 86  ? 43.70084 18.33524  42.54259  0.607 20.02313 ? 86  CYS A SG  1 
ATOM   594  N N   . THR A 1 87  ? 41.46067 16.01982  43.81891  1.000 13.21395 ? 87  THR A N   1 
ATOM   595  C CA  . THR A 1 87  ? 41.85873 14.62445  43.97602  1.000 15.03091 ? 87  THR A CA  1 
ATOM   596  C C   . THR A 1 87  ? 42.50432 14.16107  42.67935  1.000 13.37785 ? 87  THR A C   1 
ATOM   597  O O   . THR A 1 87  ? 42.04314 14.51825  41.58756  1.000 15.32426 ? 87  THR A O   1 
ATOM   598  C CB  . THR A 1 87  ? 40.67687 13.70672  44.32650  1.000 15.00771 ? 87  THR A CB  1 
ATOM   599  O OG1 . THR A 1 87  ? 40.10936 14.12851  45.57319  1.000 16.27011 ? 87  THR A OG1 1 
ATOM   600  C CG2 . THR A 1 87  ? 41.16378 12.24604  44.47993  1.000 16.21966 ? 87  THR A CG2 1 
ATOM   601  N N   . ALA A 1 88  ? 43.58247 13.38843  42.80180  1.000 15.67462 ? 88  ALA A N   1 
ATOM   602  C CA  . ALA A 1 88  ? 44.37950 12.98229  41.66032  1.000 13.59422 ? 88  ALA A CA  1 
ATOM   603  C C   . ALA A 1 88  ? 44.55113 11.46904  41.62741  1.000 15.15156 ? 88  ALA A C   1 
ATOM   604  O O   . ALA A 1 88  ? 44.58552 10.80308  42.66658  1.000 15.24691 ? 88  ALA A O   1 
ATOM   605  C CB  . ALA A 1 88  ? 45.74501 13.63278  41.73217  1.000 17.56929 ? 88  ALA A CB  1 
ATOM   606  N N   . TYR A 1 89  ? 44.66356 10.94567  40.40763  1.000 13.09397 ? 89  TYR A N   1 
ATOM   607  C CA  . TYR A 1 89  ? 44.89699 9.53360   40.13250  1.000 12.59954 ? 89  TYR A CA  1 
ATOM   608  C C   . TYR A 1 89  ? 46.34455 9.37427   39.69390  1.000 14.41575 ? 89  TYR A C   1 
ATOM   609  O O   . TYR A 1 89  ? 46.81976 10.14820  38.85689  1.000 14.66833 ? 89  TYR A O   1 
ATOM   610  C CB  . TYR A 1 89  ? 43.95088 9.05607   39.02300  1.000 12.81634 ? 89  TYR A CB  1 
ATOM   611  C CG  . TYR A 1 89  ? 42.48543 9.29672   39.34803  1.000 13.51530 ? 89  TYR A CG  1 
ATOM   612  C CD1 . TYR A 1 89  ? 41.87521 10.51001  39.05741  1.000 15.48184 ? 89  TYR A CD1 1 
ATOM   613  C CD2 . TYR A 1 89  ? 41.72149 8.31352   39.97748  1.000 13.16497 ? 89  TYR A CD2 1 
ATOM   614  C CE1 . TYR A 1 89  ? 40.53532 10.73575  39.37045  1.000 14.61539 ? 89  TYR A CE1 1 
ATOM   615  C CE2 . TYR A 1 89  ? 40.38092 8.53274   40.28880  1.000 14.21212 ? 89  TYR A CE2 1 
ATOM   616  C CZ  . TYR A 1 89  ? 39.80143 9.74479   39.98930  1.000 13.83658 ? 89  TYR A CZ  1 
ATOM   617  O OH  . TYR A 1 89  ? 38.46878 9.97474   40.29650  1.000 14.61685 ? 89  TYR A OH  1 
ATOM   618  N N   . VAL A 1 90  ? 47.03206 8.38059   40.25901  1.000 13.76427 ? 90  VAL A N   1 
ATOM   619  C CA  . VAL A 1 90  ? 48.48944 8.26250   40.19299  1.000 13.64979 ? 90  VAL A CA  1 
ATOM   620  C C   . VAL A 1 90  ? 48.87821 6.96817   39.47842  1.000 12.80573 ? 90  VAL A C   1 
ATOM   621  O O   . VAL A 1 90  ? 48.33513 5.89577   39.77472  1.000 16.57274 ? 90  VAL A O   1 
ATOM   622  C CB  . VAL A 1 90  ? 49.10538 8.29390   41.60582  1.000 14.76590 ? 90  VAL A CB  1 
ATOM   623  C CG1 . VAL A 1 90  ? 50.61771 8.14139   41.54698  1.000 15.83606 ? 90  VAL A CG1 1 
ATOM   624  C CG2 . VAL A 1 90  ? 48.72233 9.58368   42.32986  1.000 15.27078 ? 90  VAL A CG2 1 
ATOM   625  N N   . TYR A 1 91  ? 49.83967 7.06960   38.55557  1.000 14.14083 ? 91  TYR A N   1 
ATOM   626  C CA  . TYR A 1 91  ? 50.43244 5.91704   37.88171  1.000 13.78614 ? 91  TYR A CA  1 
ATOM   627  C C   . TYR A 1 91  ? 51.95027 6.00439   37.95333  1.000 14.97548 ? 91  TYR A C   1 
ATOM   628  O O   . TYR A 1 91  ? 52.52653 7.05418   37.67416  1.000 13.92115 ? 91  TYR A O   1 
ATOM   629  C CB  . TYR A 1 91  ? 49.99220 5.84909   36.41849  1.000 15.68297 ? 91  TYR A CB  1 
ATOM   630  C CG  . TYR A 1 91  ? 48.51207 5.65334   36.29396  1.000 13.16218 ? 91  TYR A CG  1 
ATOM   631  C CD1 . TYR A 1 91  ? 47.64150 6.72795   36.39694  1.000 13.73836 ? 91  TYR A CD1 1 
ATOM   632  C CD2 . TYR A 1 91  ? 47.97844 4.38888   36.08640  1.000 14.68241 ? 91  TYR A CD2 1 
ATOM   633  C CE1 . TYR A 1 91  ? 46.27734 6.55053   36.31554  1.000 14.46108 ? 91  TYR A CE1 1 
ATOM   634  C CE2 . TYR A 1 91  ? 46.60602 4.20411   35.99219  1.000 14.91329 ? 91  TYR A CE2 1 
ATOM   635  C CZ  . TYR A 1 91  ? 45.76701 5.28848   36.10661  1.000 14.59564 ? 91  TYR A CZ  1 
ATOM   636  O OH  . TYR A 1 91  ? 44.39604 5.09144   36.00626  1.000 16.04254 ? 91  TYR A OH  1 
ATOM   637  N N   . GLY A 1 92  ? 52.59641 4.89762   38.31642  1.000 14.48911 ? 92  GLY A N   1 
ATOM   638  C CA  . GLY A 1 92  ? 54.04514 4.85780   38.30682  1.000 13.39461 ? 92  GLY A CA  1 
ATOM   639  C C   . GLY A 1 92  ? 54.60326 4.74653   36.89842  1.000 13.64480 ? 92  GLY A C   1 
ATOM   640  O O   . GLY A 1 92  ? 53.96042 4.22553   35.98789  1.000 14.62302 ? 92  GLY A O   1 
ATOM   641  N N   . ARG A 1 93  ? 55.83165 5.24243   36.72131  1.000 12.76903 ? 93  ARG A N   1 
ATOM   642  C CA  . ARG A 1 93  ? 56.55289 5.11589   35.46092  1.000 11.77946 ? 93  ARG A CA  1 
ATOM   643  C C   . ARG A 1 93  ? 57.97238 4.62894   35.71375  1.000 13.53372 ? 93  ARG A C   1 
ATOM   644  O O   . ARG A 1 93  ? 58.55259 4.87004   36.77569  1.000 12.90849 ? 93  ARG A O   1 
ATOM   645  C CB  . ARG A 1 93  ? 56.59545 6.44656   34.68080  1.000 13.96880 ? 93  ARG A CB  1 
ATOM   646  C CG  . ARG A 1 93  ? 55.19948 7.05548   34.46082  1.000 13.91252 ? 93  ARG A CG  1 
ATOM   647  C CD  . ARG A 1 93  ? 55.27427 8.26833   33.54383  1.000 14.79071 ? 93  ARG A CD  1 
ATOM   648  N NE  . ARG A 1 93  ? 55.31129 7.90878   32.12484  1.000 14.67300 ? 93  ARG A NE  1 
ATOM   649  C CZ  . ARG A 1 93  ? 56.11807 8.48166   31.24260  1.000 16.85015 ? 93  ARG A CZ  1 
ATOM   650  N NH1 . ARG A 1 93  ? 56.98172 9.40970   31.64024  1.000 18.67341 ? 93  ARG A NH1 1 
ATOM   651  N NH2 . ARG A 1 93  ? 56.08174 8.11044   29.96798  1.000 17.22475 ? 93  ARG A NH2 1 
ATOM   652  N N   . GLY A 1 94  ? 58.51178 3.91321   34.73066  1.000 13.01307 ? 94  GLY A N   1 
ATOM   653  C CA  . GLY A 1 94  ? 59.90586 3.51177   34.79197  1.000 13.58653 ? 94  GLY A CA  1 
ATOM   654  C C   . GLY A 1 94  ? 60.23371 2.49976   35.86236  1.000 15.51271 ? 94  GLY A C   1 
ATOM   655  O O   . GLY A 1 94  ? 61.40647 2.34354   36.20911  1.000 17.51979 ? 94  GLY A O   1 
ATOM   656  N N   . GLY A 1 95  ? 59.22796 1.82139   36.41364  1.000 13.90875 ? 95  GLY A N   1 
ATOM   657  C CA  . GLY A 1 95  ? 59.41529 0.91084   37.52424  1.000 13.29298 ? 95  GLY A CA  1 
ATOM   658  C C   . GLY A 1 95  ? 59.15683 1.52764   38.88088  1.000 14.87254 ? 95  GLY A C   1 
ATOM   659  O O   . GLY A 1 95  ? 59.14596 0.80516   39.88315  1.000 15.58456 ? 95  GLY A O   1 
ATOM   660  N N   . TYR A 1 96  ? 58.97601 2.84136   38.94572  1.000 15.00258 ? 96  TYR A N   1 
ATOM   661  C CA  . TYR A 1 96  ? 58.77134 3.50673   40.21915  1.000 14.45404 ? 96  TYR A CA  1 
ATOM   662  C C   . TYR A 1 96  ? 57.29725 3.56275   40.58196  1.000 14.11605 ? 96  TYR A C   1 
ATOM   663  O O   . TYR A 1 96  ? 56.40815 3.26791   39.77676  1.000 14.29159 ? 96  TYR A O   1 
ATOM   664  C CB  . TYR A 1 96  ? 59.40311 4.90735   40.20186  1.000 13.47915 ? 96  TYR A CB  1 
ATOM   665  C CG  . TYR A 1 96  ? 60.89738 4.84997   40.43455  1.000 15.45849 ? 96  TYR A CG  1 
ATOM   666  C CD1 . TYR A 1 96  ? 61.74060 4.27403   39.49579  1.000 16.35388 ? 96  TYR A CD1 1 
ATOM   667  C CD2 . TYR A 1 96  ? 61.46037 5.33051   41.61385  1.000 16.36834 ? 96  TYR A CD2 1 
ATOM   668  C CE1 . TYR A 1 96  ? 63.11240 4.19068   39.71159  1.000 17.24439 ? 96  TYR A CE1 1 
ATOM   669  C CE2 . TYR A 1 96  ? 62.83746 5.25198   41.83568  1.000 15.52333 ? 96  TYR A CE2 1 
ATOM   670  C CZ  . TYR A 1 96  ? 63.64936 4.67697   40.88145  1.000 15.92004 ? 96  TYR A CZ  1 
ATOM   671  O OH  . TYR A 1 96  ? 65.02176 4.57823   41.08280  1.000 17.83240 ? 96  TYR A OH  1 
ATOM   672  N N   . TYR A 1 97  ? 57.05418 3.91709   41.83988  1.000 12.53515 ? 97  TYR A N   1 
ATOM   673  C CA  . TYR A 1 97  ? 55.72057 4.12317   42.36461  1.000 13.40052 ? 97  TYR A CA  1 
ATOM   674  C C   . TYR A 1 97  ? 55.79593 5.31701   43.30721  1.000 15.43948 ? 97  TYR A C   1 
ATOM   675  O O   . TYR A 1 97  ? 56.87923 5.72677   43.72317  1.000 14.87513 ? 97  TYR A O   1 
ATOM   676  C CB  . TYR A 1 97  ? 55.18807 2.84906   43.05786  1.000 14.35711 ? 97  TYR A CB  1 
ATOM   677  C CG  . TYR A 1 97  ? 55.92627 2.44729   44.31712  1.000 17.79959 ? 97  TYR A CG  1 
ATOM   678  C CD1 . TYR A 1 97  ? 55.58853 2.99777   45.54546  1.000 16.06457 ? 97  TYR A CD1 1 
ATOM   679  C CD2 . TYR A 1 97  ? 56.94627 1.51672   44.27817  1.000 16.90223 ? 97  TYR A CD2 1 
ATOM   680  C CE1 . TYR A 1 97  ? 56.25471 2.64286   46.69878  1.000 18.41763 ? 97  TYR A CE1 1 
ATOM   681  C CE2 . TYR A 1 97  ? 57.62080 1.14713   45.43044  1.000 19.33074 ? 97  TYR A CE2 1 
ATOM   682  C CZ  . TYR A 1 97  ? 57.27371 1.72263   46.63824  1.000 18.14265 ? 97  TYR A CZ  1 
ATOM   683  O OH  . TYR A 1 97  ? 57.94032 1.36406   47.79394  1.000 20.86668 ? 97  TYR A OH  1 
ATOM   684  N N   . LEU A 1 98  ? 54.63627 5.86628   43.63840  1.000 16.73765 ? 98  LEU A N   1 
ATOM   685  C CA  . LEU A 1 98  ? 54.54310 7.04276   44.49701  1.000 16.41888 ? 98  LEU A CA  1 
ATOM   686  C C   . LEU A 1 98  ? 54.42431 6.59874   45.94718  1.000 17.54620 ? 98  LEU A C   1 
ATOM   687  O O   . LEU A 1 98  ? 53.51720 5.83506   46.29872  1.000 17.24910 ? 98  LEU A O   1 
ATOM   688  C CB  . LEU A 1 98  ? 53.32210 7.86938   44.09639  1.000 18.17250 ? 98  LEU A CB  1 
ATOM   689  C CG  . LEU A 1 98  ? 53.07908 9.13922   44.91651  1.000 21.27777 ? 98  LEU A CG  1 
ATOM   690  C CD1 . LEU A 1 98  ? 54.27414 10.03991  44.81822  1.000 19.88221 ? 98  LEU A CD1 1 
ATOM   691  C CD2 . LEU A 1 98  ? 51.81569 9.86991   44.46394  1.000 23.13207 ? 98  LEU A CD2 1 
ATOM   692  N N   . SER A 1 99  ? 55.33767 7.08216   46.78103  1.000 18.36198 ? 99  SER A N   1 
ATOM   693  C CA  . SER A 1 99  ? 55.29279 6.79925   48.20414  1.000 19.03596 ? 99  SER A CA  1 
ATOM   694  C C   . SER A 1 99  ? 54.05167 7.41656   48.82315  1.000 23.10562 ? 99  SER A C   1 
ATOM   695  O O   . SER A 1 99  ? 53.55754 8.46085   48.39164  1.000 23.29458 ? 99  SER A O   1 
ATOM   696  C CB  . SER A 1 99  ? 56.51505 7.40953   48.88369  1.000 30.46378 ? 99  SER A CB  1 
ATOM   697  O OG  . SER A 1 99  ? 56.43559 7.25303   50.29162  1.000 34.63502 ? 99  SER A OG  1 
ATOM   698  N N   . MET A 1 100 ? 53.56152 6.76559   49.86511  1.000 28.32118 ? 100 MET A N   1 
ATOM   699  C CA  . MET A 1 100 ? 52.32730 7.15194   50.52551  1.000 32.85962 ? 100 MET A CA  1 
ATOM   700  C C   . MET A 1 100 ? 52.53691 7.71747   51.92548  1.000 33.97605 ? 100 MET A C   1 
ATOM   701  O O   . MET A 1 100 ? 51.56455 7.84523   52.67339  1.000 38.13067 ? 100 MET A O   1 
ATOM   702  C CB  . MET A 1 100 ? 51.37936 5.95183   50.52345  1.000 32.63464 ? 100 MET A CB  1 
ATOM   703  C CG  . MET A 1 100 ? 51.96921 4.73896   51.26325  1.000 32.13583 ? 100 MET A CG  1 
ATOM   704  S SD  . MET A 1 100 ? 51.92462 4.69578   53.05751  0.569 35.44835 ? 100 MET A SD  1 
ATOM   705  C CE  . MET A 1 100 ? 50.17707 4.44463   53.35383  1.000 37.14094 ? 100 MET A CE  1 
ATOM   706  N N   . TYR A 1 101 ? 53.76729 8.06704   52.30342  1.000 33.96587 ? 101 TYR A N   1 
ATOM   707  C CA  . TYR A 1 101 ? 53.98540 8.63276   53.63009  1.000 35.64425 ? 101 TYR A CA  1 
ATOM   708  C C   . TYR A 1 101 ? 53.28232 9.98547   53.76112  1.000 36.96487 ? 101 TYR A C   1 
ATOM   709  O O   . TYR A 1 101 ? 52.91009 10.62848  52.77207  1.000 32.81091 ? 101 TYR A O   1 
ATOM   710  C CB  . TYR A 1 101 ? 55.47923 8.75984   53.93590  1.000 36.10611 ? 101 TYR A CB  1 
ATOM   711  N N   . LYS A 1 102 ? 53.10010 10.41241  55.01432  1.000 32.46944 ? 102 LYS A N   1 
ATOM   712  C CA  . LYS A 1 102 ? 52.28574 11.59198  55.29453  1.000 35.89618 ? 102 LYS A CA  1 
ATOM   713  C C   . LYS A 1 102 ? 52.87529 12.85248  54.67371  1.000 35.42671 ? 102 LYS A C   1 
ATOM   714  O O   . LYS A 1 102 ? 52.13467 13.68688  54.13933  1.000 38.08003 ? 102 LYS A O   1 
ATOM   715  C CB  . LYS A 1 102 ? 52.10538 11.76822  56.80251  1.000 36.95162 ? 102 LYS A CB  1 
ATOM   716  N N   . GLY A 1 103 ? 54.19019 13.02266  54.74360  1.000 34.36042 ? 103 GLY A N   1 
ATOM   717  C CA  . GLY A 1 103 ? 54.80222 14.21343  54.19491  1.000 32.80643 ? 103 GLY A CA  1 
ATOM   718  C C   . GLY A 1 103 ? 55.36985 14.07074  52.80138  1.000 30.66945 ? 103 GLY A C   1 
ATOM   719  O O   . GLY A 1 103 ? 56.15077 14.92773  52.37430  1.000 33.53372 ? 103 GLY A O   1 
ATOM   720  N N   . ASP A 1 104 ? 54.98872 13.03123  52.06439  1.000 31.72489 ? 104 ASP A N   1 
ATOM   721  C CA  . ASP A 1 104 ? 55.64421 12.70538  50.80678  1.000 33.62240 ? 104 ASP A CA  1 
ATOM   722  C C   . ASP A 1 104 ? 54.90556 13.17372  49.55667  1.000 26.49819 ? 104 ASP A C   1 
ATOM   723  O O   . ASP A 1 104 ? 55.37386 12.87129  48.45362  1.000 30.14027 ? 104 ASP A O   1 
ATOM   724  C CB  . ASP A 1 104 ? 55.91032 11.19414  50.70227  1.000 31.80238 ? 104 ASP A CB  1 
ATOM   725  C CG  . ASP A 1 104 ? 57.11746 10.74761  51.51205  1.000 32.45442 ? 104 ASP A CG  1 
ATOM   726  O OD1 . ASP A 1 104 ? 57.87898 11.61236  51.99125  1.000 34.49466 ? 104 ASP A OD1 1 
ATOM   727  O OD2 . ASP A 1 104 ? 57.32395 9.52274   51.63995  1.000 36.80434 ? 104 ASP A OD2 1 
ATOM   728  N N   . VAL A 1 105 ? 53.76127 13.85835  49.66542  1.000 25.32778 ? 105 VAL A N   1 
ATOM   729  C CA  . VAL A 1 105 ? 53.01887 14.26319  48.46285  1.000 23.20478 ? 105 VAL A CA  1 
ATOM   730  C C   . VAL A 1 105 ? 52.41180 15.64835  48.69705  1.000 20.92643 ? 105 VAL A C   1 
ATOM   731  O O   . VAL A 1 105 ? 51.39886 15.77291  49.39298  1.000 24.17022 ? 105 VAL A O   1 
ATOM   732  C CB  . VAL A 1 105 ? 51.91437 13.26582  48.06562  1.000 22.50746 ? 105 VAL A CB  1 
ATOM   733  C CG1 . VAL A 1 105 ? 51.36495 13.63305  46.70166  1.000 21.60205 ? 105 VAL A CG1 1 
ATOM   734  C CG2 . VAL A 1 105 ? 52.38991 11.80414  48.10182  1.000 25.68679 ? 105 VAL A CG2 1 
ATOM   735  N N   . LYS A 1 106 ? 52.99126 16.68155  48.07778  1.000 18.62461 ? 106 LYS A N   1 
ATOM   736  C CA  . LYS A 1 106 ? 52.54796 18.05975  48.27243  1.000 18.19842 ? 106 LYS A CA  1 
ATOM   737  C C   . LYS A 1 106 ? 52.07649 18.67621  46.96293  1.000 18.48765 ? 106 LYS A C   1 
ATOM   738  O O   . LYS A 1 106 ? 52.64155 18.41019  45.90353  1.000 18.76723 ? 106 LYS A O   1 
ATOM   739  C CB  . LYS A 1 106 ? 53.67371 18.94200  48.81960  1.000 19.79267 ? 106 LYS A CB  1 
ATOM   740  C CG  . LYS A 1 106 ? 54.24035 18.50289  50.16064  1.000 22.86384 ? 106 LYS A CG  1 
ATOM   741  C CD  . LYS A 1 106 ? 55.44617 19.37739  50.53288  1.000 25.19548 ? 106 LYS A CD  1 
ATOM   742  C CE  . LYS A 1 106 ? 55.63009 19.50283  52.03266  1.000 30.81046 ? 106 LYS A CE  1 
ATOM   743  N NZ  . LYS A 1 106 ? 55.75719 18.17186  52.66143  1.000 31.59919 ? 106 LYS A NZ  1 
ATOM   744  N N   . LEU A 1 107 ? 51.03665 19.50326  47.04641  1.000 17.74488 ? 107 LEU A N   1 
ATOM   745  C CA  . LEU A 1 107 ? 50.54762 20.29947  45.92269  1.000 16.86195 ? 107 LEU A CA  1 
ATOM   746  C C   . LEU A 1 107 ? 50.59207 21.76552  46.33702  1.000 18.07661 ? 107 LEU A C   1 
ATOM   747  O O   . LEU A 1 107 ? 50.00553 22.13924  47.35554  1.000 18.69183 ? 107 LEU A O   1 
ATOM   748  C CB  . LEU A 1 107 ? 49.12499 19.87935  45.53575  1.000 15.61363 ? 107 LEU A CB  1 
ATOM   749  C CG  . LEU A 1 107 ? 48.49082 20.59424  44.34364  1.000 16.19384 ? 107 LEU A CG  1 
ATOM   750  C CD1 . LEU A 1 107 ? 49.24084 20.28005  43.04958  1.000 16.82061 ? 107 LEU A CD1 1 
ATOM   751  C CD2 . LEU A 1 107 ? 47.01722 20.20617  44.23018  1.000 15.74864 ? 107 LEU A CD2 1 
ATOM   752  N N   . ASN A 1 108 ? 51.30836 22.58849  45.57263  1.000 17.42657 ? 108 ASN A N   1 
ATOM   753  C CA  . ASN A 1 108 ? 51.51383 23.99272  45.95712  1.000 17.76376 ? 108 ASN A CA  1 
ATOM   754  C C   . ASN A 1 108 ? 52.06672 24.10494  47.37992  1.000 19.99537 ? 108 ASN A C   1 
ATOM   755  O O   . ASN A 1 108 ? 51.70664 25.01378  48.13797  1.000 22.37134 ? 108 ASN A O   1 
ATOM   756  C CB  . ASN A 1 108 ? 50.23163 24.81502  45.78318  1.000 18.87116 ? 108 ASN A CB  1 
ATOM   757  C CG  . ASN A 1 108 ? 50.50398 26.31138  45.71405  1.000 22.25305 ? 108 ASN A CG  1 
ATOM   758  O OD1 . ASN A 1 108 ? 51.56595 26.74083  45.25272  1.000 24.37588 ? 108 ASN A OD1 1 
ATOM   759  N ND2 . ASN A 1 108 ? 49.56115 27.10937  46.20389  1.000 26.81428 ? 108 ASN A ND2 1 
ATOM   760  N N   . SER A 1 109 ? 52.94704 23.16458  47.74163  1.000 19.69128 ? 109 SER A N   1 
ATOM   761  C CA  . SER A 1 109 ? 53.62173 23.05819  49.03535  1.000 20.97169 ? 109 SER A CA  1 
ATOM   762  C C   . SER A 1 109 ? 52.72787 22.55544  50.16468  1.000 22.50072 ? 109 SER A C   1 
ATOM   763  O O   . SER A 1 109 ? 53.17376 22.50524  51.32020  1.000 23.07439 ? 109 SER A O   1 
ATOM   764  C CB  . SER A 1 109 ? 54.34277 24.34842  49.44788  1.000 23.77912 ? 109 SER A CB  1 
ATOM   765  O OG  . SER A 1 109 ? 55.39865 24.61819  48.54201  1.000 31.63221 ? 109 SER A OG  1 
ATOM   766  N N   . VAL A 1 110 ? 51.49458 22.15666  49.87563  1.000 18.87601 ? 110 VAL A N   1 
ATOM   767  C CA  . VAL A 1 110 ? 50.55373 21.73258  50.90573  1.000 18.98447 ? 110 VAL A CA  1 
ATOM   768  C C   . VAL A 1 110 ? 50.50251 20.21088  50.93791  1.000 20.49076 ? 110 VAL A C   1 
ATOM   769  O O   . VAL A 1 110 ? 50.31371 19.56604  49.89798  1.000 19.34099 ? 110 VAL A O   1 
ATOM   770  C CB  . VAL A 1 110 ? 49.15525 22.32358  50.66230  1.000 20.76267 ? 110 VAL A CB  1 
ATOM   771  C CG1 . VAL A 1 110 ? 48.20908 21.89935  51.78505  1.000 22.18014 ? 110 VAL A CG1 1 
ATOM   772  C CG2 . VAL A 1 110 ? 49.21982 23.84731  50.55663  1.000 21.45710 ? 110 VAL A CG2 1 
ATOM   773  N N   . ASP A 1 111 ? 50.64462 19.64181  52.13543  1.000 21.21701 ? 111 ASP A N   1 
ATOM   774  C CA  . ASP A 1 111 ? 50.55104 18.19761  52.31907  1.000 23.02327 ? 111 ASP A CA  1 
ATOM   775  C C   . ASP A 1 111 ? 49.14309 17.69006  52.01420  1.000 19.86630 ? 111 ASP A C   1 
ATOM   776  O O   . ASP A 1 111 ? 48.14188 18.33736  52.33762  1.000 20.19191 ? 111 ASP A O   1 
ATOM   777  C CB  . ASP A 1 111 ? 50.85817 17.84757  53.77479  1.000 28.63597 ? 111 ASP A CB  1 
ATOM   778  C CG  . ASP A 1 111 ? 52.34322 17.68604  54.05481  1.000 33.41882 ? 111 ASP A CG  1 
ATOM   779  O OD1 . ASP A 1 111 ? 53.14141 17.42860  53.12118  1.000 29.66635 ? 111 ASP A OD1 1 
ATOM   780  O OD2 . ASP A 1 111 ? 52.71163 17.80084  55.24156  1.000 38.45161 ? 111 ASP A OD2 1 
ATOM   781  N N   . HIS A 1 112 ? 49.06991 16.49560  51.43610  1.000 18.07380 ? 112 HIS A N   1 
ATOM   782  C CA  . HIS A 1 112 ? 47.78225 15.88075  51.13452  1.000 19.34849 ? 112 HIS A CA  1 
ATOM   783  C C   . HIS A 1 112 ? 47.01952 15.53791  52.41373  1.000 20.65576 ? 112 HIS A C   1 
ATOM   784  O O   . HIS A 1 112 ? 47.58261 15.47844  53.50930  1.000 22.72256 ? 112 HIS A O   1 
ATOM   785  C CB  . HIS A 1 112 ? 47.99144 14.60138  50.32916  1.000 18.53803 ? 112 HIS A CB  1 
ATOM   786  C CG  . HIS A 1 112 ? 48.65894 13.50618  51.09991  1.000 23.81790 ? 112 HIS A CG  1 
ATOM   787  N ND1 . HIS A 1 112 ? 50.02707 13.33044  51.11223  1.000 25.61507 ? 112 HIS A ND1 1 
ATOM   788  C CD2 . HIS A 1 112 ? 48.14551 12.53085  51.88687  1.000 24.53157 ? 112 HIS A CD2 1 
ATOM   789  C CE1 . HIS A 1 112 ? 50.32574 12.29298  51.87409  1.000 27.42642 ? 112 HIS A CE1 1 
ATOM   790  N NE2 . HIS A 1 112 ? 49.20243 11.78905  52.35359  1.000 28.87673 ? 112 HIS A NE2 1 
ATOM   791  N N   . ASN A 1 113 ? 45.71648 15.29460  52.25693  1.000 19.30326 ? 113 ASN A N   1 
ATOM   792  C CA  . ASN A 1 113 ? 44.85416 14.86072  53.35634  1.000 21.49806 ? 113 ASN A CA  1 
ATOM   793  C C   . ASN A 1 113 ? 44.56715 13.36609  53.35222  1.000 24.22143 ? 113 ASN A C   1 
ATOM   794  O O   . ASN A 1 113 ? 44.47104 12.75689  54.42209  1.000 23.71731 ? 113 ASN A O   1 
ATOM   795  C CB  . ASN A 1 113 ? 43.51773 15.60540  53.33523  1.000 23.17866 ? 113 ASN A CB  1 
ATOM   796  C CG  . ASN A 1 113 ? 43.66953 17.08196  53.59039  1.000 24.64887 ? 113 ASN A CG  1 
ATOM   797  O OD1 . ASN A 1 113 ? 43.81112 17.87313  52.66133  1.000 22.88044 ? 113 ASN A OD1 1 
ATOM   798  N ND2 . ASN A 1 113 ? 43.60318 17.47159  54.86032  1.000 26.58892 ? 113 ASN A ND2 1 
ATOM   799  N N   . GLU A 1 114 ? 44.39325 12.76747  52.17984  1.000 19.77586 ? 114 GLU A N   1 
ATOM   800  C CA  . GLU A 1 114 ? 44.00606 11.36988  52.07934  1.000 19.43881 ? 114 GLU A CA  1 
ATOM   801  C C   . GLU A 1 114 ? 44.74980 10.73773  50.91773  1.000 20.86558 ? 114 GLU A C   1 
ATOM   802  O O   . GLU A 1 114 ? 45.01264 11.38917  49.89930  1.000 18.29059 ? 114 GLU A O   1 
ATOM   803  C CB  . GLU A 1 114 ? 42.50418 11.20797  51.80491  1.000 19.40589 ? 114 GLU A CB  1 
ATOM   804  C CG  . GLU A 1 114 ? 41.58031 11.62080  52.94526  1.000 20.42403 ? 114 GLU A CG  1 
ATOM   805  C CD  . GLU A 1 114 ? 41.73478 10.75351  54.18755  1.000 23.63481 ? 114 GLU A CD  1 
ATOM   806  O OE1 . GLU A 1 114 ? 42.19100 9.59677   54.06128  1.000 24.39676 ? 114 GLU A OE1 1 
ATOM   807  O OE2 . GLU A 1 114 ? 41.37216 11.22710  55.28762  1.000 24.28216 ? 114 GLU A OE2 1 
ATOM   808  N N   . ILE A 1 115 ? 45.06734 9.45227   51.07905  1.000 19.91410 ? 115 ILE A N   1 
ATOM   809  C CA  . ILE A 1 115 ? 45.64882 8.62382   50.02995  1.000 20.76237 ? 115 ILE A CA  1 
ATOM   810  C C   . ILE A 1 115 ? 44.92663 7.28207   49.99650  1.000 20.27955 ? 115 ILE A C   1 
ATOM   811  O O   . ILE A 1 115 ? 44.53778 6.74428   51.04072  1.000 21.65636 ? 115 ILE A O   1 
ATOM   812  C CB  . ILE A 1 115 ? 47.16552 8.40714   50.21684  1.000 24.21252 ? 115 ILE A CB  1 
ATOM   813  C CG1 . ILE A 1 115 ? 47.93209 9.71922   50.08114  1.000 25.14293 ? 115 ILE A CG1 1 
ATOM   814  C CG2 . ILE A 1 115 ? 47.69686 7.38481   49.23025  1.000 22.87055 ? 115 ILE A CG2 1 
ATOM   815  C CD1 . ILE A 1 115 ? 49.44535 9.53996   50.06787  1.000 29.87636 ? 115 ILE A CD1 1 
ATOM   816  N N   . ILE A 1 116 ? 44.73447 6.75553   48.79227  1.000 17.59364 ? 116 ILE A N   1 
ATOM   817  C CA  . ILE A 1 116 ? 44.31354 5.37460   48.56883  1.000 19.36994 ? 116 ILE A CA  1 
ATOM   818  C C   . ILE A 1 116 ? 45.46316 4.67295   47.86043  1.000 18.37161 ? 116 ILE A C   1 
ATOM   819  O O   . ILE A 1 116 ? 46.13283 5.28265   47.01713  1.000 18.44184 ? 116 ILE A O   1 
ATOM   820  C CB  . ILE A 1 116 ? 43.01020 5.32365   47.74691  1.000 19.36565 ? 116 ILE A CB  1 
ATOM   821  C CG1 . ILE A 1 116 ? 41.82578 5.80284   48.60153  1.000 16.35599 ? 116 ILE A CG1 1 
ATOM   822  C CG2 . ILE A 1 116 ? 42.75507 3.93232   47.19077  1.000 16.47733 ? 116 ILE A CG2 1 
ATOM   823  C CD1 . ILE A 1 116 ? 40.53382 5.92981   47.82629  1.000 16.49029 ? 116 ILE A CD1 1 
ATOM   824  N N   . SER A 1 117 ? 45.70603 3.40198   48.19972  1.000 17.33048 ? 117 SER A N   1 
ATOM   825  C CA  . SER A 1 117 ? 46.95135 2.75224   47.80053  1.000 18.84456 ? 117 SER A CA  1 
ATOM   826  C C   . SER A 1 117 ? 46.74550 1.29443   47.40760  1.000 18.68597 ? 117 SER A C   1 
ATOM   827  O O   . SER A 1 117 ? 45.73934 0.66353   47.73646  1.000 18.48772 ? 117 SER A O   1 
ATOM   828  C CB  . SER A 1 117 ? 47.99191 2.77655   48.92708  1.000 21.85719 ? 117 SER A CB  1 
ATOM   829  O OG  . SER A 1 117 ? 48.30532 4.09809   49.31036  1.000 24.24931 ? 117 SER A OG  1 
ATOM   830  N N   . MET A 1 118 ? 47.75539 0.75367   46.73290  1.000 19.79900 ? 118 MET A N   1 
ATOM   831  C CA  . MET A 1 118 ? 47.91452 -0.67917  46.53991  1.000 17.09275 ? 118 MET A CA  1 
ATOM   832  C C   . MET A 1 118 ? 48.92712 -1.17378  47.56657  1.000 20.37841 ? 118 MET A C   1 
ATOM   833  O O   . MET A 1 118 ? 49.79925 -0.42259  48.01287  1.000 23.61162 ? 118 MET A O   1 
ATOM   834  C CB  . MET A 1 118 ? 48.48201 -0.94156  45.15006  1.000 20.52049 ? 118 MET A CB  1 
ATOM   835  C CG  . MET A 1 118 ? 47.56572 -0.52123  44.04290  1.000 25.17570 ? 118 MET A CG  1 
ATOM   836  S SD  . MET A 1 118 ? 48.30522 -0.95518  42.47504  0.549 32.35935 ? 118 MET A SD  1 
ATOM   837  C CE  . MET A 1 118 ? 49.64486 0.21447   42.37636  1.000 30.26761 ? 118 MET A CE  1 
ATOM   838  N N   . VAL A 1 119 ? 48.83951 -2.46405  47.89006  1.000 19.72550 ? 119 VAL A N   1 
ATOM   839  C CA  . VAL A 1 119 ? 49.45753 -3.05651  49.07513  1.000 21.88451 ? 119 VAL A CA  1 
ATOM   840  C C   . VAL A 1 119 ? 50.61097 -3.95719  48.65043  1.000 23.64789 ? 119 VAL A C   1 
ATOM   841  O O   . VAL A 1 119 ? 50.43322 -4.84622  47.80887  1.000 22.93356 ? 119 VAL A O   1 
ATOM   842  C CB  . VAL A 1 119 ? 48.41988 -3.87721  49.86477  1.000 26.88421 ? 119 VAL A CB  1 
ATOM   843  C CG1 . VAL A 1 119 ? 48.99755 -4.33812  51.19707  1.000 30.49585 ? 119 VAL A CG1 1 
ATOM   844  C CG2 . VAL A 1 119 ? 47.13927 -3.08180  50.05819  1.000 30.53493 ? 119 VAL A CG2 1 
ATOM   845  N N   . GLY A 1 120 ? 51.77844 -3.75797  49.26267  1.000 25.85478 ? 120 GLY A N   1 
ATOM   846  C CA  . GLY A 1 120 ? 52.96118 -4.54744  48.95273  1.000 26.94046 ? 120 GLY A CA  1 
ATOM   847  C C   . GLY A 1 120 ? 53.52507 -5.33322  50.12422  1.000 31.14579 ? 120 GLY A C   1 
ATOM   848  O O   . GLY A 1 120 ? 52.77441 -5.85700  50.94680  1.000 34.19507 ? 120 GLY A O   1 
ATOM   849  N N   . ILE A 1 124 ? 55.57365 -1.74402  52.32101  1.000 37.13643 ? 124 ILE A N   1 
ATOM   850  C CA  . ILE A 1 124 ? 55.45018 -1.25188  50.95337  1.000 31.30389 ? 124 ILE A CA  1 
ATOM   851  C C   . ILE A 1 124 ? 53.99750 -0.95593  50.58841  1.000 32.64420 ? 124 ILE A C   1 
ATOM   852  O O   . ILE A 1 124 ? 53.12051 -1.79894  50.77097  1.000 31.77811 ? 124 ILE A O   1 
ATOM   853  C CB  . ILE A 1 124 ? 56.12237 -2.20910  49.94622  1.000 30.03423 ? 124 ILE A CB  1 
ATOM   854  C CG1 . ILE A 1 124 ? 57.59752 -2.39827  50.30991  1.000 32.53890 ? 124 ILE A CG1 1 
ATOM   855  C CG2 . ILE A 1 124 ? 55.97756 -1.68854  48.51501  1.000 29.43484 ? 124 ILE A CG2 1 
ATOM   856  C CD1 . ILE A 1 124 ? 58.37774 -3.21880  49.31030  1.000 35.24184 ? 124 ILE A CD1 1 
ATOM   857  N N   . ALA A 1 125 ? 53.75430 0.25479   50.08302  1.000 27.85052 ? 125 ALA A N   1 
ATOM   858  C CA  . ALA A 1 125 ? 52.45010 0.64836   49.57073  1.000 27.01728 ? 125 ALA A CA  1 
ATOM   859  C C   . ALA A 1 125 ? 52.65587 1.71265   48.50207  1.000 24.60962 ? 125 ALA A C   1 
ATOM   860  O O   . ALA A 1 125 ? 53.53336 2.57179   48.63845  1.000 26.15797 ? 125 ALA A O   1 
ATOM   861  C CB  . ALA A 1 125 ? 51.55363 1.19943   50.68197  1.000 26.17578 ? 125 ALA A CB  1 
ATOM   862  N N   . ALA A 1 126 ? 51.85596 1.64711   47.43875  1.000 22.11129 ? 126 ALA A N   1 
ATOM   863  C CA  . ALA A 1 126 ? 51.97058 2.56378   46.30745  1.000 20.13639 ? 126 ALA A CA  1 
ATOM   864  C C   . ALA A 1 126 ? 50.68948 3.37781   46.19524  1.000 20.36466 ? 126 ALA A C   1 
ATOM   865  O O   . ALA A 1 126 ? 49.59923 2.81232   46.07505  1.000 18.01905 ? 126 ALA A O   1 
ATOM   866  C CB  . ALA A 1 126 ? 52.23154 1.80121   45.00921  1.000 19.64230 ? 126 ALA A CB  1 
ATOM   867  N N   . ALA A 1 127 ? 50.81649 4.70303   46.21772  1.000 17.71264 ? 127 ALA A N   1 
ATOM   868  C CA  . ALA A 1 127 ? 49.63490 5.55292   46.16366  1.000 18.96637 ? 127 ALA A CA  1 
ATOM   869  C C   . ALA A 1 127 ? 49.00650 5.49471   44.77777  1.000 18.27889 ? 127 ALA A C   1 
ATOM   870  O O   . ALA A 1 127 ? 49.70743 5.57901   43.76365  1.000 20.52780 ? 127 ALA A O   1 
ATOM   871  C CB  . ALA A 1 127 ? 50.02880 6.99659   46.48830  1.000 19.23972 ? 127 ALA A CB  1 
ATOM   872  N N   . THR A 1 128 ? 47.67704 5.35013   44.72951  1.000 16.29608 ? 128 THR A N   1 
ATOM   873  C CA  . THR A 1 128 ? 46.92799 5.39817   43.48350  1.000 16.28876 ? 128 THR A CA  1 
ATOM   874  C C   . THR A 1 128 ? 45.96598 6.56817   43.40335  1.000 15.29241 ? 128 THR A C   1 
ATOM   875  O O   . THR A 1 128 ? 45.57475 6.95177   42.29351  1.000 16.12466 ? 128 THR A O   1 
ATOM   876  C CB  . THR A 1 128 ? 46.14069 4.09732   43.26658  1.000 16.42651 ? 128 THR A CB  1 
ATOM   877  O OG1 . THR A 1 128 ? 45.22089 3.89989   44.34502  1.000 18.99083 ? 128 THR A OG1 1 
ATOM   878  C CG2 . THR A 1 128 ? 47.09609 2.90603   43.19698  1.000 19.54752 ? 128 THR A CG2 1 
ATOM   879  N N   . MET A 1 129 ? 45.55697 7.12768   44.53769  1.000 15.46273 ? 129 MET A N   1 
ATOM   880  C CA  . MET A 1 129 ? 44.70264 8.29811   44.56454  1.000 15.75397 ? 129 MET A CA  1 
ATOM   881  C C   . MET A 1 129 ? 45.21742 9.16879   45.70288  1.000 16.25296 ? 129 MET A C   1 
ATOM   882  O O   . MET A 1 129 ? 45.59198 8.65580   46.76449  1.000 18.11218 ? 129 MET A O   1 
ATOM   883  C CB  . MET A 1 129 ? 43.27408 7.83787   44.86595  1.000 15.34901 ? 129 MET A CB  1 
ATOM   884  C CG  . MET A 1 129 ? 42.54330 7.42167   43.62600  1.000 16.60021 ? 129 MET A CG  1 
ATOM   885  S SD  . MET A 1 129 ? 40.82195 7.03192   43.95842  0.897 15.78851 ? 129 MET A SD  1 
ATOM   886  C CE  . MET A 1 129 ? 40.15499 8.66954   44.14330  1.000 17.07263 ? 129 MET A CE  1 
ATOM   887  N N   . VAL A 1 130 ? 45.28889 10.47837  45.46680  1.000 15.46655 ? 130 VAL A N   1 
ATOM   888  C CA  . VAL A 1 130 ? 45.76934 11.42980  46.47051  1.000 16.80715 ? 130 VAL A CA  1 
ATOM   889  C C   . VAL A 1 130 ? 44.86265 12.65827  46.45933  1.000 15.13970 ? 130 VAL A C   1 
ATOM   890  O O   . VAL A 1 130 ? 44.46795 13.13661  45.39155  1.000 16.29232 ? 130 VAL A O   1 
ATOM   891  C CB  . VAL A 1 130 ? 47.24279 11.82687  46.22616  1.000 16.71023 ? 130 VAL A CB  1 
ATOM   892  C CG1 . VAL A 1 130 ? 47.75218 12.72519  47.33691  1.000 18.16061 ? 130 VAL A CG1 1 
ATOM   893  C CG2 . VAL A 1 130 ? 48.12989 10.60170  46.12757  1.000 22.35807 ? 130 VAL A CG2 1 
ATOM   894  N N   . SER A 1 131 ? 44.53680 13.18109  47.64972  1.000 16.03106 ? 131 SER A N   1 
ATOM   895  C CA  . SER A 1 131 ? 43.53065 14.23422  47.75710  1.000 15.90682 ? 131 SER A CA  1 
ATOM   896  C C   . SER A 1 131 ? 43.96648 15.35630  48.69259  1.000 14.83047 ? 131 SER A C   1 
ATOM   897  O O   . SER A 1 131 ? 44.61790 15.11016  49.71218  1.000 17.51642 ? 131 SER A O   1 
ATOM   898  C CB  . SER A 1 131 ? 42.20488 13.65043  48.24798  1.000 17.12769 ? 131 SER A CB  1 
ATOM   899  O OG  . SER A 1 131 ? 41.18417 14.61754  48.18858  1.000 16.16456 ? 131 SER A OG  1 
ATOM   900  N N   . TRP A 1 132 ? 43.58295 16.58678  48.33421  1.000 17.61793 ? 132 TRP A N   1 
ATOM   901  C CA  . TRP A 1 132 ? 43.83200 17.79860  49.11820  1.000 16.23214 ? 132 TRP A CA  1 
ATOM   902  C C   . TRP A 1 132 ? 42.49127 18.48466  49.36485  1.000 17.50038 ? 132 TRP A C   1 
ATOM   903  O O   . TRP A 1 132 ? 41.81577 18.87300  48.40505  1.000 17.17750 ? 132 TRP A O   1 
ATOM   904  C CB  . TRP A 1 132 ? 44.75240 18.76477  48.34685  1.000 16.03816 ? 132 TRP A CB  1 
ATOM   905  C CG  . TRP A 1 132 ? 46.14609 18.23947  48.13403  1.000 16.49393 ? 132 TRP A CG  1 
ATOM   906  C CD1 . TRP A 1 132 ? 47.24552 18.50275  48.89885  1.000 17.11108 ? 132 TRP A CD1 1 
ATOM   907  C CD2 . TRP A 1 132 ? 46.58891 17.35685  47.08858  1.000 15.26181 ? 132 TRP A CD2 1 
ATOM   908  N NE1 . TRP A 1 132 ? 48.33806 17.83131  48.40958  1.000 18.93011 ? 132 TRP A NE1 1 
ATOM   909  C CE2 . TRP A 1 132 ? 47.96689 17.12405  47.29678  1.000 17.79971 ? 132 TRP A CE2 1 
ATOM   910  C CE3 . TRP A 1 132 ? 45.95819 16.74679  46.00038  1.000 14.18293 ? 132 TRP A CE3 1 
ATOM   911  C CZ2 . TRP A 1 132 ? 48.72523 16.30419  46.45646  1.000 18.07687 ? 132 TRP A CZ2 1 
ATOM   912  C CZ3 . TRP A 1 132 ? 46.71495 15.93195  45.15903  1.000 15.86024 ? 132 TRP A CZ3 1 
ATOM   913  C CH2 . TRP A 1 132 ? 48.08490 15.71389  45.39906  1.000 16.29379 ? 132 TRP A CH2 1 
ATOM   914  N N   . LYS A 1 133 ? 42.12039 18.65361  50.64430  1.000 19.19615 ? 133 LYS A N   1 
ATOM   915  C CA  . LYS A 1 133 ? 40.81950 19.23975  50.98847  1.000 19.65504 ? 133 LYS A CA  1 
ATOM   916  C C   . LYS A 1 133 ? 40.62721 20.64179  50.40432  1.000 18.14098 ? 133 LYS A C   1 
ATOM   917  O O   . LYS A 1 133 ? 39.51933 20.99278  49.98497  1.000 19.45826 ? 133 LYS A O   1 
ATOM   918  C CB  . LYS A 1 133 ? 40.61694 19.29584  52.51640  1.000 23.09166 ? 133 LYS A CB  1 
ATOM   919  C CG  . LYS A 1 133 ? 40.59204 17.99292  53.35327  1.000 34.57385 ? 133 LYS A CG  1 
ATOM   920  C CD  . LYS A 1 133 ? 39.37532 17.09395  53.13181  1.000 33.13391 ? 133 LYS A CD  1 
ATOM   921  C CE  . LYS A 1 133 ? 39.40619 15.79709  53.98644  1.000 35.21646 ? 133 LYS A CE  1 
ATOM   922  N NZ  . LYS A 1 133 ? 39.25666 15.95540  55.47935  1.000 39.69673 ? 133 LYS A NZ  1 
ATOM   923  N N   . SER A 1 134 ? 41.67250 21.47209  50.39433  1.000 17.75515 ? 134 SER A N   1 
ATOM   924  C CA  . SER A 1 134 ? 41.44738 22.88788  50.13051  1.000 20.76064 ? 134 SER A CA  1 
ATOM   925  C C   . SER A 1 134 ? 42.50454 23.48543  49.21579  1.000 22.67956 ? 134 SER A C   1 
ATOM   926  O O   . SER A 1 134 ? 42.74365 24.69883  49.25440  1.000 22.71001 ? 134 SER A O   1 
ATOM   927  C CB  . SER A 1 134 ? 41.36242 23.68205  51.43716  1.000 24.83886 ? 134 SER A CB  1 
ATOM   928  O OG  . SER A 1 134 ? 42.55020 23.50744  52.18923  1.000 29.65538 ? 134 SER A OG  1 
ATOM   929  N N   . THR A 1 135 ? 43.13903 22.66148  48.38557  1.000 18.99906 ? 135 THR A N   1 
ATOM   930  C CA  . THR A 1 135 ? 44.12458 23.12573  47.41374  1.000 17.26963 ? 135 THR A CA  1 
ATOM   931  C C   . THR A 1 135 ? 43.65828 22.71154  46.02665  1.000 19.01159 ? 135 THR A C   1 
ATOM   932  O O   . THR A 1 135 ? 43.25420 21.56469  45.82876  1.000 18.14222 ? 135 THR A O   1 
ATOM   933  C CB  . THR A 1 135 ? 45.49462 22.51636  47.71630  1.000 19.48584 ? 135 THR A CB  1 
ATOM   934  O OG1 . THR A 1 135 ? 45.85933 22.82230  49.07127  1.000 20.44161 ? 135 THR A OG1 1 
ATOM   935  C CG2 . THR A 1 135 ? 46.56454 23.06095  46.76606  1.000 17.91111 ? 135 THR A CG2 1 
ATOM   936  N N   . LYS A 1 136 ? 43.69885 23.64167  45.07719  1.000 17.52741 ? 136 LYS A N   1 
ATOM   937  C CA  . LYS A 1 136 ? 43.22989 23.39717  43.72369  1.000 16.31179 ? 136 LYS A CA  1 
ATOM   938  C C   . LYS A 1 136 ? 44.39483 23.14078  42.77309  1.000 17.27859 ? 136 LYS A C   1 
ATOM   939  O O   . LYS A 1 136 ? 45.48844 23.69566  42.92025  1.000 18.43038 ? 136 LYS A O   1 
ATOM   940  C CB  . LYS A 1 136 ? 42.40115 24.57326  43.20446  1.000 18.48077 ? 136 LYS A CB  1 
ATOM   941  C CG  . LYS A 1 136 ? 41.09069 24.81341  43.96526  1.000 21.73911 ? 136 LYS A CG  1 
ATOM   942  C CD  . LYS A 1 136 ? 39.94226 24.01085  43.34650  1.000 21.79124 ? 136 LYS A CD  1 
ATOM   943  C CE  . LYS A 1 136 ? 38.83577 23.71892  44.35782  1.000 20.47155 ? 136 LYS A CE  1 
ATOM   944  N NZ  . LYS A 1 136 ? 37.89496 22.69387  43.83854  1.000 17.24713 ? 136 LYS A NZ  1 
ATOM   945  N N   . ALA A 1 137 ? 44.15059 22.27762  41.79565  1.000 16.24693 ? 137 ALA A N   1 
ATOM   946  C CA  . ALA A 1 137 ? 45.09395 22.10389  40.70098  1.000 16.36329 ? 137 ALA A CA  1 
ATOM   947  C C   . ALA A 1 137 ? 44.97803 23.28368  39.74003  1.000 16.43453 ? 137 ALA A C   1 
ATOM   948  O O   . ALA A 1 137 ? 43.87716 23.77602  39.46851  1.000 17.93348 ? 137 ALA A O   1 
ATOM   949  C CB  . ALA A 1 137 ? 44.81021 20.79535  39.95831  1.000 13.86336 ? 137 ALA A CB  1 
ATOM   950  N N   . ALA A 1 138 ? 46.12832 23.74807  39.24754  1.000 16.46040 ? 138 ALA A N   1 
ATOM   951  C CA  . ALA A 1 138 ? 46.19429 24.83184  38.27642  1.000 16.80697 ? 138 ALA A CA  1 
ATOM   952  C C   . ALA A 1 138 ? 47.54153 24.74630  37.57910  1.000 15.74164 ? 138 ALA A C   1 
ATOM   953  O O   . ALA A 1 138 ? 48.50477 24.20414  38.12256  1.000 17.40216 ? 138 ALA A O   1 
ATOM   954  C CB  . ALA A 1 138 ? 46.06438 26.20059  38.95353  1.000 16.82504 ? 138 ALA A CB  1 
ATOM   955  N N   . ALA A 1 139 ? 47.61078 25.32231  36.38560  1.000 16.10917 ? 139 ALA A N   1 
ATOM   956  C CA  . ALA A 1 139 ? 48.84209 25.22013  35.61782  1.000 16.97762 ? 139 ALA A CA  1 
ATOM   957  C C   . ALA A 1 139 ? 49.96646 25.96743  36.31709  1.000 17.49097 ? 139 ALA A C   1 
ATOM   958  O O   . ALA A 1 139 ? 49.76907 27.05264  36.87207  1.000 18.21941 ? 139 ALA A O   1 
ATOM   959  C CB  . ALA A 1 139 ? 48.64245 25.77774  34.21022  1.000 17.55484 ? 139 ALA A CB  1 
ATOM   960  N N   . GLY A 1 140 ? 51.15346 25.37412  36.30415  1.000 16.50125 ? 140 GLY A N   1 
ATOM   961  C CA  . GLY A 1 140 ? 52.32456 26.06325  36.79327  1.000 18.98381 ? 140 GLY A CA  1 
ATOM   962  C C   . GLY A 1 140 ? 52.63235 25.85679  38.25612  1.000 19.65650 ? 140 GLY A C   1 
ATOM   963  O O   . GLY A 1 140 ? 53.73824 26.20685  38.69049  1.000 23.33839 ? 140 GLY A O   1 
ATOM   964  N N   . ILE A 1 141 ? 51.71390 25.27925  39.03143  1.000 16.27804 ? 141 ILE A N   1 
ATOM   965  C CA  . ILE A 1 141 ? 52.00979 25.05296  40.43730  1.000 17.98136 ? 141 ILE A CA  1 
ATOM   966  C C   . ILE A 1 141 ? 52.77921 23.75164  40.59615  1.000 17.70982 ? 141 ILE A C   1 
ATOM   967  O O   . ILE A 1 141 ? 52.84093 22.93073  39.67403  1.000 16.88024 ? 141 ILE A O   1 
ATOM   968  C CB  . ILE A 1 141 ? 50.76749 25.10421  41.33810  1.000 18.80244 ? 141 ILE A CB  1 
ATOM   969  C CG1 . ILE A 1 141 ? 49.86858 23.90961  41.06852  1.000 18.25473 ? 141 ILE A CG1 1 
ATOM   970  C CG2 . ILE A 1 141 ? 50.02881 26.43362  41.16518  1.000 21.39531 ? 141 ILE A CG2 1 
ATOM   971  C CD1 . ILE A 1 141 ? 48.68247 23.81583  42.02029  1.000 21.25307 ? 141 ILE A CD1 1 
ATOM   972  N N   . SER A 1 142 ? 53.36622 23.56947  41.76727  1.000 19.49832 ? 142 SER A N   1 
ATOM   973  C CA  . SER A 1 142 ? 54.33983 22.52524  42.01820  1.000 18.81872 ? 142 SER A CA  1 
ATOM   974  C C   . SER A 1 142 ? 53.70098 21.28849  42.64002  1.000 17.98954 ? 142 SER A C   1 
ATOM   975  O O   . SER A 1 142 ? 52.79140 21.38566  43.46655  1.000 19.80676 ? 142 SER A O   1 
ATOM   976  C CB  . SER A 1 142 ? 55.42579 23.07357  42.94327  1.000 23.39960 ? 142 SER A CB  1 
ATOM   977  O OG  . SER A 1 142 ? 54.96642 23.10876  44.28887  1.000 29.45496 ? 142 SER A OG  1 
ATOM   978  N N   . PHE A 1 143 ? 54.17884 20.12594  42.21133  1.000 17.26974 ? 143 PHE A N   1 
ATOM   979  C CA  . PHE A 1 143 ? 53.82724 18.83134  42.78361  1.000 15.95872 ? 143 PHE A CA  1 
ATOM   980  C C   . PHE A 1 143 ? 55.14151 18.24149  43.27473  1.000 17.14278 ? 143 PHE A C   1 
ATOM   981  O O   . PHE A 1 143 ? 56.03825 17.96693  42.46699  1.000 17.09809 ? 143 PHE A O   1 
ATOM   982  C CB  . PHE A 1 143 ? 53.20085 17.93154  41.72111  1.000 16.71969 ? 143 PHE A CB  1 
ATOM   983  C CG  . PHE A 1 143 ? 52.86950 16.54680  42.20949  1.000 15.55473 ? 143 PHE A CG  1 
ATOM   984  C CD1 . PHE A 1 143 ? 51.76876 16.33045  43.02186  1.000 17.60519 ? 143 PHE A CD1 1 
ATOM   985  C CD2 . PHE A 1 143 ? 53.64907 15.45799  41.83936  1.000 17.51503 ? 143 PHE A CD2 1 
ATOM   986  C CE1 . PHE A 1 143 ? 51.45806 15.05146  43.45663  1.000 17.66622 ? 143 PHE A CE1 1 
ATOM   987  C CE2 . PHE A 1 143 ? 53.34674 14.18277  42.27517  1.000 15.95181 ? 143 PHE A CE2 1 
ATOM   988  C CZ  . PHE A 1 143 ? 52.25337 13.97331  43.08033  1.000 16.51631 ? 143 PHE A CZ  1 
ATOM   989  N N   . LYS A 1 144 ? 55.27104 18.07750  44.58941  1.000 15.53690 ? 144 LYS A N   1 
ATOM   990  C CA  . LYS A 1 144 ? 56.49246 17.56179  45.20169  1.000 16.91927 ? 144 LYS A CA  1 
ATOM   991  C C   . LYS A 1 144 ? 56.19692 16.18987  45.78961  1.000 16.91532 ? 144 LYS A C   1 
ATOM   992  O O   . LYS A 1 144 ? 55.22667 16.02735  46.53734  1.000 18.07142 ? 144 LYS A O   1 
ATOM   993  C CB  . LYS A 1 144 ? 57.00382 18.50510  46.29543  1.000 20.28858 ? 144 LYS A CB  1 
ATOM   994  N N   . TYR A 1 145 ? 57.02503 15.20622  45.45211  1.000 15.70397 ? 145 TYR A N   1 
ATOM   995  C CA  . TYR A 1 145 ? 56.69726 13.83077  45.79129  1.000 16.31887 ? 145 TYR A CA  1 
ATOM   996  C C   . TYR A 1 145 ? 57.96652 13.03755  46.04489  1.000 14.75602 ? 145 TYR A C   1 
ATOM   997  O O   . TYR A 1 145 ? 59.07714 13.44497  45.68603  1.000 15.87072 ? 145 TYR A O   1 
ATOM   998  C CB  . TYR A 1 145 ? 55.87548 13.16075  44.68361  1.000 17.51020 ? 145 TYR A CB  1 
ATOM   999  C CG  . TYR A 1 145 ? 56.70586 12.83893  43.46555  1.000 15.78673 ? 145 TYR A CG  1 
ATOM   1000 C CD1 . TYR A 1 145 ? 56.97746 13.81706  42.51426  1.000 15.99077 ? 145 TYR A CD1 1 
ATOM   1001 C CD2 . TYR A 1 145 ? 57.24193 11.57187  43.27913  1.000 15.95373 ? 145 TYR A CD2 1 
ATOM   1002 C CE1 . TYR A 1 145 ? 57.75564 13.54192  41.41019  1.000 14.40274 ? 145 TYR A CE1 1 
ATOM   1003 C CE2 . TYR A 1 145 ? 58.03172 11.28652  42.18154  1.000 16.75030 ? 145 TYR A CE2 1 
ATOM   1004 C CZ  . TYR A 1 145 ? 58.27646 12.26296  41.24473  1.000 15.63497 ? 145 TYR A CZ  1 
ATOM   1005 O OH  . TYR A 1 145 ? 59.06961 11.96591  40.16029  1.000 18.67812 ? 145 TYR A OH  1 
ATOM   1006 N N   . LEU A 1 146 ? 57.78357 11.85861  46.63002  1.000 15.78398 ? 146 LEU A N   1 
ATOM   1007 C CA  . LEU A 1 146 ? 58.88251 10.91909  46.78156  1.000 16.06081 ? 146 LEU A CA  1 
ATOM   1008 C C   . LEU A 1 146 ? 58.52175 9.64101   46.03832  1.000 16.35272 ? 146 LEU A C   1 
ATOM   1009 O O   . LEU A 1 146 ? 57.45169 9.06120   46.27069  1.000 19.40261 ? 146 LEU A O   1 
ATOM   1010 C CB  . LEU A 1 146 ? 59.22683 10.70332  48.25717  1.000 21.88740 ? 146 LEU A CB  1 
ATOM   1011 C CG  . LEU A 1 146 ? 60.42577 9.80826   48.56891  1.000 25.03685 ? 146 LEU A CG  1 
ATOM   1012 C CD1 . LEU A 1 146 ? 61.19271 10.40545  49.72661  1.000 31.92076 ? 146 LEU A CD1 1 
ATOM   1013 C CD2 . LEU A 1 146 ? 59.92339 8.45791   48.96177  1.000 29.39021 ? 146 LEU A CD2 1 
ATOM   1014 N N   . GLY A 1 147 ? 59.37561 9.25590   45.09365  1.000 14.54130 ? 147 GLY A N   1 
ATOM   1015 C CA  . GLY A 1 147 ? 59.18919 8.03690   44.32654  1.000 15.06804 ? 147 GLY A CA  1 
ATOM   1016 C C   . GLY A 1 147 ? 60.14532 6.95746   44.80554  1.000 15.67679 ? 147 GLY A C   1 
ATOM   1017 O O   . GLY A 1 147 ? 61.29681 7.23631   45.13926  1.000 16.10647 ? 147 GLY A O   1 
ATOM   1018 N N   . LYS A 1 148 ? 59.65024 5.72326   44.81996  1.000 16.69815 ? 148 LYS A N   1 
ATOM   1019 C CA  . LYS A 1 148 ? 60.40310 4.57066   45.29008  1.000 16.99926 ? 148 LYS A CA  1 
ATOM   1020 C C   . LYS A 1 148 ? 60.30440 3.46821   44.24472  1.000 15.15492 ? 148 LYS A C   1 
ATOM   1021 O O   . LYS A 1 148 ? 59.48607 3.53393   43.32029  1.000 15.62544 ? 148 LYS A O   1 
ATOM   1022 C CB  . LYS A 1 148 ? 59.82784 4.06178   46.62284  1.000 18.23225 ? 148 LYS A CB  1 
ATOM   1023 C CG  . LYS A 1 148 ? 59.90611 5.06305   47.77177  1.000 23.38717 ? 148 LYS A CG  1 
ATOM   1024 C CD  . LYS A 1 148 ? 61.29790 5.17515   48.29392  1.000 25.21603 ? 148 LYS A CD  1 
ATOM   1025 C CE  . LYS A 1 148 ? 61.68478 3.93138   49.07784  1.000 27.59933 ? 148 LYS A CE  1 
ATOM   1026 N NZ  . LYS A 1 148 ? 63.06064 4.08668   49.64529  1.000 30.36141 ? 148 LYS A NZ  1 
ATOM   1027 N N   . ASN A 1 149 ? 61.12783 2.42888   44.40719  1.000 16.02216 ? 149 ASN A N   1 
ATOM   1028 C CA  . ASN A 1 149 ? 61.05729 1.27348   43.52361  1.000 15.93585 ? 149 ASN A CA  1 
ATOM   1029 C C   . ASN A 1 149 ? 61.29299 0.00036   44.32659  1.000 17.02440 ? 149 ASN A C   1 
ATOM   1030 O O   . ASN A 1 149 ? 61.67372 0.03799   45.49699  1.000 19.37076 ? 149 ASN A O   1 
ATOM   1031 C CB  . ASN A 1 149 ? 61.99906 1.42293   42.32391  1.000 16.37135 ? 149 ASN A CB  1 
ATOM   1032 C CG  . ASN A 1 149 ? 63.43601 1.13380   42.68567  1.000 17.84465 ? 149 ASN A CG  1 
ATOM   1033 O OD1 . ASN A 1 149 ? 63.86280 -0.00677  42.66747  1.000 18.03620 ? 149 ASN A OD1 1 
ATOM   1034 N ND2 . ASN A 1 149 ? 64.18425 2.17318   43.02441  1.000 18.62377 ? 149 ASN A ND2 1 
ATOM   1035 N N   . LEU A 1 150 ? 61.04402 -1.13789  43.68515  1.000 15.21695 ? 150 LEU A N   1 
ATOM   1036 C CA  . LEU A 1 150 ? 61.08975 -2.42094  44.37278  1.000 17.60279 ? 150 LEU A CA  1 
ATOM   1037 C C   . LEU A 1 150 ? 62.44126 -3.11869  44.27384  1.000 18.91395 ? 150 LEU A C   1 
ATOM   1038 O O   . LEU A 1 150 ? 62.61772 -4.16719  44.90460  1.000 21.36577 ? 150 LEU A O   1 
ATOM   1039 C CB  . LEU A 1 150 ? 60.01520 -3.34708  43.80071  1.000 16.49127 ? 150 LEU A CB  1 
ATOM   1040 C CG  . LEU A 1 150 ? 58.59389 -2.81071  44.01032  1.000 17.27544 ? 150 LEU A CG  1 
ATOM   1041 C CD1 . LEU A 1 150 ? 57.60319 -3.68870  43.26419  1.000 18.84260 ? 150 LEU A CD1 1 
ATOM   1042 C CD2 . LEU A 1 150 ? 58.24311 -2.76634  45.48920  1.000 19.41962 ? 150 LEU A CD2 1 
ATOM   1043 N N   . ILE A 1 151 ? 63.37996 -2.58826  43.49543  1.000 18.27061 ? 151 ILE A N   1 
ATOM   1044 C CA  . ILE A 1 151 ? 64.69670 -3.21539  43.33089  1.000 18.94219 ? 151 ILE A CA  1 
ATOM   1045 C C   . ILE A 1 151 ? 65.71781 -2.64063  44.30470  1.000 20.55068 ? 151 ILE A C   1 
ATOM   1046 O O   . ILE A 1 151 ? 66.40828 -3.37971  45.01456  1.000 18.88927 ? 151 ILE A O   1 
ATOM   1047 C CB  . ILE A 1 151 ? 65.17771 -3.08335  41.86803  1.000 18.59365 ? 151 ILE A CB  1 
ATOM   1048 C CG1 . ILE A 1 151 ? 64.22183 -3.80552  40.91239  1.000 19.63089 ? 151 ILE A CG1 1 
ATOM   1049 C CG2 . ILE A 1 151 ? 66.62513 -3.59252  41.72778  1.000 21.04239 ? 151 ILE A CG2 1 
ATOM   1050 C CD1 . ILE A 1 151 ? 64.66401 -3.78718  39.47426  1.000 19.70905 ? 151 ILE A CD1 1 
ATOM   1051 N N   . THR A 1 152 ? 65.84785 -1.31788  44.33599  1.000 19.81064 ? 152 THR A N   1 
ATOM   1052 C CA  . THR A 1 152 ? 66.81239 -0.63795  45.18461  1.000 20.61998 ? 152 THR A CA  1 
ATOM   1053 C C   . THR A 1 152 ? 66.07196 0.26616   46.15652  1.000 20.61721 ? 152 THR A C   1 
ATOM   1054 O O   . THR A 1 152 ? 64.85429 0.46621   46.06297  1.000 18.61796 ? 152 THR A O   1 
ATOM   1055 C CB  . THR A 1 152 ? 67.75084 0.23255   44.34767  1.000 20.38214 ? 152 THR A CB  1 
ATOM   1056 O OG1 . THR A 1 152 ? 67.01358 1.35670   43.85590  1.000 20.08697 ? 152 THR A OG1 1 
ATOM   1057 C CG2 . THR A 1 152 ? 68.32837 -0.55890  43.17363  1.000 19.43212 ? 152 THR A CG2 1 
ATOM   1058 N N   . SER A 1 153 ? 66.83030 0.83162   47.09185  1.000 19.39513 ? 153 SER A N   1 
ATOM   1059 C CA  . SER A 1 153 ? 66.27920 1.75957   48.06678  1.000 20.94181 ? 153 SER A CA  1 
ATOM   1060 C C   . SER A 1 153 ? 66.36631 3.21624   47.62075  1.000 17.97960 ? 153 SER A C   1 
ATOM   1061 O O   . SER A 1 153 ? 66.23609 4.11218   48.46306  1.000 20.48462 ? 153 SER A O   1 
ATOM   1062 C CB  . SER A 1 153 ? 66.93453 1.55703   49.43462  1.000 24.58935 ? 153 SER A CB  1 
ATOM   1063 O OG  . SER A 1 153 ? 68.32531 1.78436   49.36496  1.000 27.81481 ? 153 SER A OG  1 
ATOM   1064 N N   . THR A 1 154 ? 66.57269 3.47224   46.32382  1.000 17.65728 ? 154 THR A N   1 
ATOM   1065 C CA  . THR A 1 154 ? 66.57673 4.84279   45.81007  1.000 18.39750 ? 154 THR A CA  1 
ATOM   1066 C C   . THR A 1 154 ? 65.34925 5.60669   46.29328  1.000 17.42850 ? 154 THR A C   1 
ATOM   1067 O O   . THR A 1 154 ? 64.21627 5.12171   46.19794  1.000 18.85278 ? 154 THR A O   1 
ATOM   1068 C CB  . THR A 1 154 ? 66.56147 4.84061   44.27430  1.000 18.12424 ? 154 THR A CB  1 
ATOM   1069 O OG1 . THR A 1 154 ? 67.71235 4.17095   43.75025  1.000 21.58392 ? 154 THR A OG1 1 
ATOM   1070 C CG2 . THR A 1 154 ? 66.52646 6.26788   43.75071  1.000 18.38340 ? 154 THR A CG2 1 
ATOM   1071 N N   . SER A 1 155 ? 65.56786 6.81612   46.79539  1.000 15.66181 ? 155 SER A N   1 
ATOM   1072 C CA  . SER A 1 155 ? 64.48077 7.72391   47.15500  1.000 18.04654 ? 155 SER A CA  1 
ATOM   1073 C C   . SER A 1 155 ? 64.53723 8.88604   46.17174  1.000 17.78772 ? 155 SER A C   1 
ATOM   1074 O O   . SER A 1 155 ? 65.43552 9.73272   46.26068  1.000 17.74790 ? 155 SER A O   1 
ATOM   1075 C CB  . SER A 1 155 ? 64.65122 8.23218   48.58896  1.000 20.72951 ? 155 SER A CB  1 
ATOM   1076 O OG  . SER A 1 155 ? 64.59725 7.17142   49.52748  1.000 26.70298 ? 155 SER A OG  1 
ATOM   1077 N N   . HIS A 1 156 ? 63.59635 8.92934   45.22559  1.000 16.31723 ? 156 HIS A N   1 
ATOM   1078 C CA  . HIS A 1 156 ? 63.58490 10.01375  44.24412  1.000 15.81335 ? 156 HIS A CA  1 
ATOM   1079 C C   . HIS A 1 156 ? 62.69278 11.12934  44.76940  1.000 16.71874 ? 156 HIS A C   1 
ATOM   1080 O O   . HIS A 1 156 ? 61.46501 11.03071  44.71288  1.000 15.63101 ? 156 HIS A O   1 
ATOM   1081 C CB  . HIS A 1 156 ? 63.10600 9.54437   42.87356  1.000 15.93330 ? 156 HIS A CB  1 
ATOM   1082 C CG  . HIS A 1 156 ? 63.03252 10.65626  41.87376  1.000 16.10364 ? 156 HIS A CG  1 
ATOM   1083 N ND1 . HIS A 1 156 ? 64.12037 11.04923  41.12284  1.000 16.53862 ? 156 HIS A ND1 1 
ATOM   1084 C CD2 . HIS A 1 156 ? 62.01928 11.49065  41.53834  1.000 16.57651 ? 156 HIS A CD2 1 
ATOM   1085 C CE1 . HIS A 1 156 ? 63.78088 12.08521  40.37367  1.000 16.73059 ? 156 HIS A CE1 1 
ATOM   1086 N NE2 . HIS A 1 156 ? 62.50498 12.35725  40.59019  1.000 16.71894 ? 156 HIS A NE2 1 
ATOM   1087 N N   . SER A 1 157 ? 63.30181 12.18467  45.30042  1.000 15.52507 ? 157 SER A N   1 
ATOM   1088 C CA  . SER A 1 157 ? 62.55933 13.37761  45.70305  1.000 15.84175 ? 157 SER A CA  1 
ATOM   1089 C C   . SER A 1 157 ? 62.43718 14.29799  44.50097  1.000 17.54220 ? 157 SER A C   1 
ATOM   1090 O O   . SER A 1 157 ? 63.41610 14.92682  44.08716  1.000 16.93242 ? 157 SER A O   1 
ATOM   1091 C CB  . SER A 1 157 ? 63.22129 14.10119  46.87163  1.000 17.09776 ? 157 SER A CB  1 
ATOM   1092 O OG  . SER A 1 157 ? 63.48217 13.20104  47.92707  1.000 23.33786 ? 157 SER A OG  1 
ATOM   1093 N N   . GLY A 1 158 ? 61.23810 14.38339  43.94568  1.000 15.41336 ? 158 GLY A N   1 
ATOM   1094 C CA  . GLY A 1 158 ? 60.99192 15.16539  42.75335  1.000 15.88232 ? 158 GLY A CA  1 
ATOM   1095 C C   . GLY A 1 158 ? 60.08144 16.34652  43.01974  1.000 15.76881 ? 158 GLY A C   1 
ATOM   1096 O O   . GLY A 1 158 ? 59.25692 16.32565  43.94031  1.000 16.58749 ? 158 GLY A O   1 
ATOM   1097 N N   . SER A 1 159 ? 60.24790 17.38442  42.20688  1.000 17.48664 ? 159 SER A N   1 
ATOM   1098 C CA  . SER A 1 159 ? 59.31277 18.49710  42.12266  1.000 18.49544 ? 159 SER A CA  1 
ATOM   1099 C C   . SER A 1 159 ? 59.01726 18.71116  40.65002  1.000 20.24315 ? 159 SER A C   1 
ATOM   1100 O O   . SER A 1 159 ? 59.94306 18.92389  39.85972  1.000 20.69606 ? 159 SER A O   1 
ATOM   1101 C CB  . SER A 1 159 ? 59.89392 19.77974  42.71801  1.000 24.01224 ? 159 SER A CB  1 
ATOM   1102 O OG  . SER A 1 159 ? 60.19469 19.61967  44.08853  1.000 31.96417 ? 159 SER A OG  1 
ATOM   1103 N N   . VAL A 1 160 ? 57.73767 18.64305  40.28205  1.000 18.01365 ? 160 VAL A N   1 
ATOM   1104 C CA  . VAL A 1 160 ? 57.30674 18.78910  38.90007  1.000 19.56822 ? 160 VAL A CA  1 
ATOM   1105 C C   . VAL A 1 160 ? 56.11716 19.74118  38.84236  1.000 20.05162 ? 160 VAL A C   1 
ATOM   1106 O O   . VAL A 1 160 ? 55.38180 19.92265  39.81427  1.000 23.30758 ? 160 VAL A O   1 
ATOM   1107 C CB  . VAL A 1 160 ? 56.96879 17.43891  38.25262  1.000 17.40648 ? 160 VAL A CB  1 
ATOM   1108 C CG1 . VAL A 1 160 ? 58.24970 16.62831  38.05781  1.000 21.44866 ? 160 VAL A CG1 1 
ATOM   1109 C CG2 . VAL A 1 160 ? 55.96155 16.67961  39.11550  1.000 19.16241 ? 160 VAL A CG2 1 
ATOM   1110 N N   . THR A 1 161 ? 55.92761 20.35351  37.68313  1.000 16.63622 ? 161 THR A N   1 
ATOM   1111 C CA  . THR A 1 161 ? 54.96260 21.43295  37.54232  1.000 16.50081 ? 161 THR A CA  1 
ATOM   1112 C C   . THR A 1 161 ? 53.72478 20.95027  36.78823  1.000 15.49474 ? 161 THR A C   1 
ATOM   1113 O O   . THR A 1 161 ? 53.83148 20.20914  35.80558  1.000 16.36137 ? 161 THR A O   1 
ATOM   1114 C CB  . THR A 1 161 ? 55.62463 22.59767  36.81033  1.000 16.93717 ? 161 THR A CB  1 
ATOM   1115 O OG1 . THR A 1 161 ? 56.68053 23.12493  37.63339  1.000 20.87609 ? 161 THR A OG1 1 
ATOM   1116 C CG2 . THR A 1 161 ? 54.64457 23.68434  36.51785  1.000 19.71333 ? 161 THR A CG2 1 
ATOM   1117 N N   . LEU A 1 162 ? 52.55089 21.37535  37.25645  1.000 14.27300 ? 162 LEU A N   1 
ATOM   1118 C CA  . LEU A 1 162 ? 51.30040 20.96788  36.63106  1.000 13.68218 ? 162 LEU A CA  1 
ATOM   1119 C C   . LEU A 1 162 ? 51.13069 21.58024  35.24826  1.000 14.40362 ? 162 LEU A C   1 
ATOM   1120 O O   . LEU A 1 162 ? 51.44874 22.75354  35.02744  1.000 15.99969 ? 162 LEU A O   1 
ATOM   1121 C CB  . LEU A 1 162 ? 50.10584 21.34530  37.50563  1.000 15.49385 ? 162 LEU A CB  1 
ATOM   1122 C CG  . LEU A 1 162 ? 49.70052 20.27918  38.51905  1.000 13.20720 ? 162 LEU A CG  1 
ATOM   1123 C CD1 . LEU A 1 162 ? 50.75710 20.07899  39.60141  1.000 14.16928 ? 162 LEU A CD1 1 
ATOM   1124 C CD2 . LEU A 1 162 ? 48.35840 20.66399  39.12242  1.000 14.91867 ? 162 LEU A CD2 1 
ATOM   1125 N N   . VAL A 1 163 ? 50.56141 20.78386  34.33972  1.000 12.79325 ? 163 VAL A N   1 
ATOM   1126 C CA  . VAL A 1 163 ? 50.27998 21.16107  32.95973  1.000 12.80753 ? 163 VAL A CA  1 
ATOM   1127 C C   . VAL A 1 163 ? 48.77982 21.05267  32.71962  1.000 14.17356 ? 163 VAL A C   1 
ATOM   1128 O O   . VAL A 1 163 ? 48.13614 20.10390  33.18172  1.000 14.26934 ? 163 VAL A O   1 
ATOM   1129 C CB  . VAL A 1 163 ? 51.04101 20.23493  31.99004  1.000 12.33761 ? 163 VAL A CB  1 
ATOM   1130 C CG1 . VAL A 1 163 ? 50.86076 20.65576  30.54915  1.000 14.80314 ? 163 VAL A CG1 1 
ATOM   1131 C CG2 . VAL A 1 163 ? 52.52977 20.16804  32.35072  1.000 13.98500 ? 163 VAL A CG2 1 
ATOM   1132 N N   . ALA A 1 164 ? 48.22210 22.01196  31.98355  1.000 14.84366 ? 164 ALA A N   1 
ATOM   1133 C CA  . ALA A 1 164 ? 46.82782 21.90618  31.57181  1.000 13.97530 ? 164 ALA A CA  1 
ATOM   1134 C C   . ALA A 1 164 ? 46.61918 20.66738  30.69997  1.000 17.05646 ? 164 ALA A C   1 
ATOM   1135 O O   . ALA A 1 164 ? 47.45954 20.33481  29.85755  1.000 15.41479 ? 164 ALA A O   1 
ATOM   1136 C CB  . ALA A 1 164 ? 46.41641 23.17548  30.81826  1.000 15.88099 ? 164 ALA A CB  1 
ATOM   1137 N N   . ALA A 1 165 ? 45.50277 19.96689  30.92890  1.000 15.14631 ? 165 ALA A N   1 
ATOM   1138 C CA  . ALA A 1 165 ? 45.17521 18.79568  30.12601  1.000 15.23854 ? 165 ALA A CA  1 
ATOM   1139 C C   . ALA A 1 165 ? 45.07193 19.19515  28.65441  1.000 18.33440 ? 165 ALA A C   1 
ATOM   1140 O O   . ALA A 1 165 ? 44.62542 20.30634  28.34347  1.000 20.92189 ? 165 ALA A O   1 
ATOM   1141 C CB  . ALA A 1 165 ? 43.84433 18.18181  30.58601  1.000 16.37001 ? 165 ALA A CB  1 
ATOM   1142 N N   . PRO A 1 166 ? 45.49875 18.32599  27.72247  1.000 17.29201 ? 166 PRO A N   1 
ATOM   1143 C CA  . PRO A 1 166 ? 45.46862 18.66421  26.29403  1.000 22.18024 ? 166 PRO A CA  1 
ATOM   1144 C C   . PRO A 1 166 ? 44.06060 18.89300  25.76716  1.000 25.57091 ? 166 PRO A C   1 
ATOM   1145 O O   . PRO A 1 166 ? 43.10058 18.27171  26.23425  1.000 26.94106 ? 166 PRO A O   1 
ATOM   1146 C CB  . PRO A 1 166 ? 46.09719 17.44298  25.61113  1.000 21.33490 ? 166 PRO A CB  1 
ATOM   1147 C CG  . PRO A 1 166 ? 46.20582 16.38980  26.64058  1.000 19.12274 ? 166 PRO A CG  1 
ATOM   1148 C CD  . PRO A 1 166 ? 46.15681 17.03135  27.98956  1.000 18.10494 ? 166 PRO A CD  1 
ATOM   1149 O OXT . PRO A 1 166 ? 43.87029 19.71997  24.86911  1.000 28.44614 ? 166 PRO A OXT 1 
ATOM   1150 N N   . GLU B 1 5   ? 46.29723 15.81883  -20.33241 1.000 36.74935 ? 5   GLU B N   1 
ATOM   1151 C CA  . GLU B 1 5   ? 45.15439 15.13720  -19.73544 1.000 36.96193 ? 5   GLU B CA  1 
ATOM   1152 C C   . GLU B 1 5   ? 45.35625 14.88033  -18.24462 1.000 31.52530 ? 5   GLU B C   1 
ATOM   1153 O O   . GLU B 1 5   ? 46.36321 15.29194  -17.66485 1.000 34.00508 ? 5   GLU B O   1 
ATOM   1154 C CB  . GLU B 1 5   ? 44.88917 13.81621  -20.45976 1.000 36.94614 ? 5   GLU B CB  1 
ATOM   1155 N N   . ALA B 1 6   ? 44.38851 14.20079  -17.63359 1.000 35.54466 ? 6   ALA B N   1 
ATOM   1156 C CA  . ALA B 1 6   ? 44.44750 13.83854  -16.22610 1.000 31.81711 ? 6   ALA B CA  1 
ATOM   1157 C C   . ALA B 1 6   ? 45.01933 12.43514  -16.05492 1.000 36.56200 ? 6   ALA B C   1 
ATOM   1158 O O   . ALA B 1 6   ? 44.79417 11.54944  -16.88487 1.000 36.59688 ? 6   ALA B O   1 
ATOM   1159 C CB  . ALA B 1 6   ? 43.04768 13.87306  -15.61829 1.000 31.48645 ? 6   ALA B CB  1 
ATOM   1160 N N   . SER B 1 7   ? 45.77467 12.24182  -14.96810 1.000 30.54994 ? 7   SER B N   1 
ATOM   1161 C CA  . SER B 1 7   ? 46.12110 10.89386  -14.51539 1.000 27.63885 ? 7   SER B CA  1 
ATOM   1162 C C   . SER B 1 7   ? 45.92584 10.71571  -13.00708 1.000 28.62129 ? 7   SER B C   1 
ATOM   1163 O O   . SER B 1 7   ? 44.87389 11.08095  -12.47382 1.000 24.24201 ? 7   SER B O   1 
ATOM   1164 C CB  . SER B 1 7   ? 47.49893 10.42653  -15.00860 1.000 34.00427 ? 7   SER B CB  1 
ATOM   1165 O OG  . SER B 1 7   ? 48.49679 11.42234  -14.89261 1.000 35.23320 ? 7   SER B OG  1 
ATOM   1166 N N   . LYS B 1 8   ? 46.92167 10.16333  -12.31396 1.000 27.24545 ? 8   LYS B N   1 
ATOM   1167 C CA  . LYS B 1 8   ? 46.71256 9.58217   -10.98408 1.000 25.62055 ? 8   LYS B CA  1 
ATOM   1168 C C   . LYS B 1 8   ? 46.14140 10.58051  -9.97735  1.000 21.03829 ? 8   LYS B C   1 
ATOM   1169 O O   . LYS B 1 8   ? 46.70191 11.65893  -9.77107  1.000 21.61553 ? 8   LYS B O   1 
ATOM   1170 C CB  . LYS B 1 8   ? 48.04638 9.06506   -10.45090 1.000 28.38927 ? 8   LYS B CB  1 
ATOM   1171 C CG  . LYS B 1 8   ? 48.80501 8.16446   -11.40504 1.000 30.10879 ? 8   LYS B CG  1 
ATOM   1172 C CD  . LYS B 1 8   ? 49.97407 7.50776   -10.69316 1.000 33.70515 ? 8   LYS B CD  1 
ATOM   1173 C CE  . LYS B 1 8   ? 51.06863 8.52139   -10.38798 1.000 37.08167 ? 8   LYS B CE  1 
ATOM   1174 N NZ  . LYS B 1 8   ? 52.44137 7.93331   -10.43785 1.000 42.37412 ? 8   LYS B NZ  1 
ATOM   1175 N N   . GLY B 1 9   ? 45.05769 10.18009  -9.29867  1.000 19.60030 ? 9   GLY B N   1 
ATOM   1176 C CA  . GLY B 1 9   ? 44.39187 11.00529  -8.30919  1.000 18.06037 ? 9   GLY B CA  1 
ATOM   1177 C C   . GLY B 1 9   ? 43.30642 11.89748  -8.86460  1.000 14.83207 ? 9   GLY B C   1 
ATOM   1178 O O   . GLY B 1 9   ? 42.49837 12.42095  -8.09075  1.000 15.22356 ? 9   GLY B O   1 
ATOM   1179 N N   . LEU B 1 10  ? 43.27375 12.08454  -10.17722 1.000 16.76190 ? 10  LEU B N   1 
ATOM   1180 C CA  . LEU B 1 10  ? 42.26290 12.87855  -10.84983 1.000 16.39297 ? 10  LEU B CA  1 
ATOM   1181 C C   . LEU B 1 10  ? 41.40405 11.96179  -11.70757 1.000 20.92137 ? 10  LEU B C   1 
ATOM   1182 O O   . LEU B 1 10  ? 41.79352 10.84401  -12.04356 1.000 20.47502 ? 10  LEU B O   1 
ATOM   1183 C CB  . LEU B 1 10  ? 42.90746 13.97230  -11.71751 1.000 15.33119 ? 10  LEU B CB  1 
ATOM   1184 C CG  . LEU B 1 10  ? 43.79114 15.01134  -11.00832 1.000 16.26748 ? 10  LEU B CG  1 
ATOM   1185 C CD1 . LEU B 1 10  ? 44.30617 16.04463  -11.98512 1.000 18.08378 ? 10  LEU B CD1 1 
ATOM   1186 C CD2 . LEU B 1 10  ? 43.03484 15.68984  -9.87912  1.000 15.82806 ? 10  LEU B CD2 1 
ATOM   1187 N N   . GLN B 1 11  ? 40.21268 12.44279  -12.03919 1.000 18.39501 ? 11  GLN B N   1 
ATOM   1188 C CA  . GLN B 1 11  ? 39.30013 11.70669  -12.89709 1.000 20.33025 ? 11  GLN B CA  1 
ATOM   1189 C C   . GLN B 1 11  ? 38.52892 12.71358  -13.73183 1.000 22.97310 ? 11  GLN B C   1 
ATOM   1190 O O   . GLN B 1 11  ? 38.39658 13.88476  -13.36434 1.000 21.10348 ? 11  GLN B O   1 
ATOM   1191 C CB  . GLN B 1 11  ? 38.34635 10.85698  -12.05328 1.000 21.14518 ? 11  GLN B CB  1 
ATOM   1192 C CG  . GLN B 1 11  ? 37.52897 11.71463  -11.11220 1.000 24.18600 ? 11  GLN B CG  1 
ATOM   1193 C CD  . GLN B 1 11  ? 36.57073 10.93837  -10.24021 1.000 27.44368 ? 11  GLN B CD  1 
ATOM   1194 O OE1 . GLN B 1 11  ? 36.48631 9.70812   -10.32188 1.000 27.50594 ? 11  GLN B OE1 1 
ATOM   1195 N NE2 . GLN B 1 11  ? 35.84670 11.65963  -9.37465  1.000 26.73844 ? 11  GLN B NE2 1 
ATOM   1196 N N   . VAL B 1 12  ? 38.02494 12.24694  -14.87045 1.000 22.90328 ? 12  VAL B N   1 
ATOM   1197 C CA  . VAL B 1 12  ? 37.23308 13.06470  -15.77871 1.000 23.91207 ? 12  VAL B CA  1 
ATOM   1198 C C   . VAL B 1 12  ? 35.87188 12.40701  -15.93278 1.000 25.53485 ? 12  VAL B C   1 
ATOM   1199 O O   . VAL B 1 12  ? 35.78357 11.21239  -16.24295 1.000 26.67910 ? 12  VAL B O   1 
ATOM   1200 C CB  . VAL B 1 12  ? 37.92155 13.22897  -17.14634 1.000 25.39435 ? 12  VAL B CB  1 
ATOM   1201 C CG1 . VAL B 1 12  ? 37.04907 14.05334  -18.08211 1.000 26.75046 ? 12  VAL B CG1 1 
ATOM   1202 C CG2 . VAL B 1 12  ? 39.27903 13.88037  -16.98675 1.000 25.28002 ? 12  VAL B CG2 1 
ATOM   1203 N N   . THR B 1 13  ? 34.81450 13.17618  -15.68127 1.000 22.38863 ? 13  THR B N   1 
ATOM   1204 C CA  . THR B 1 13  ? 33.45457 12.69570  -15.87118 1.000 23.83424 ? 13  THR B CA  1 
ATOM   1205 C C   . THR B 1 13  ? 32.66300 13.73980  -16.64201 1.000 27.38425 ? 13  THR B C   1 
ATOM   1206 O O   . THR B 1 13  ? 33.24215 14.68172  -17.20416 1.000 23.64554 ? 13  THR B O   1 
ATOM   1207 C CB  . THR B 1 13  ? 32.77332 12.42503  -14.52425 1.000 24.49562 ? 13  THR B CB  1 
ATOM   1208 O OG1 . THR B 1 13  ? 32.55910 13.66618  -13.83560 1.000 25.56230 ? 13  THR B OG1 1 
ATOM   1209 C CG2 . THR B 1 13  ? 33.61202 11.49794  -13.65809 1.000 28.33266 ? 13  THR B CG2 1 
ATOM   1210 N N   . ALA B 1 14  ? 31.33655 13.58729  -16.65264 1.000 27.28129 ? 14  ALA B N   1 
ATOM   1211 C CA  . ALA B 1 14  ? 30.48666 14.58354  -17.29443 1.000 27.12576 ? 14  ALA B CA  1 
ATOM   1212 C C   . ALA B 1 14  ? 30.69145 15.96284  -16.68630 1.000 30.25383 ? 14  ALA B C   1 
ATOM   1213 O O   . ALA B 1 14  ? 30.49006 16.97614  -17.36735 1.000 29.11619 ? 14  ALA B O   1 
ATOM   1214 C CB  . ALA B 1 14  ? 29.01918 14.16722  -17.19309 1.000 27.90054 ? 14  ALA B CB  1 
ATOM   1215 N N   . SER B 1 15  ? 31.11807 16.02161  -15.42314 1.000 25.65463 ? 15  SER B N   1 
ATOM   1216 C CA  . SER B 1 15  ? 31.25953 17.27672  -14.69822 1.000 22.23035 ? 15  SER B CA  1 
ATOM   1217 C C   . SER B 1 15  ? 32.60879 17.95522  -14.90881 1.000 19.95157 ? 15  SER B C   1 
ATOM   1218 O O   . SER B 1 15  ? 32.83129 19.02018  -14.33341 1.000 20.46461 ? 15  SER B O   1 
ATOM   1219 C CB  . SER B 1 15  ? 31.05860 17.05075  -13.19398 1.000 22.79756 ? 15  SER B CB  1 
ATOM   1220 O OG  . SER B 1 15  ? 29.72016 16.69912  -12.88116 1.000 25.61492 ? 15  SER B OG  1 
ATOM   1221 N N   . GLY B 1 16  ? 33.50955 17.37819  -15.69172 1.000 20.41214 ? 16  GLY B N   1 
ATOM   1222 C CA  . GLY B 1 16  ? 34.84405 17.92866  -15.84017 1.000 21.89129 ? 16  GLY B CA  1 
ATOM   1223 C C   . GLY B 1 16  ? 35.88333 17.13862  -15.06870 1.000 19.67310 ? 16  GLY B C   1 
ATOM   1224 O O   . GLY B 1 16  ? 35.71681 15.95486  -14.77163 1.000 21.49012 ? 16  GLY B O   1 
ATOM   1225 N N   . VAL B 1 17  ? 36.98522 17.80859  -14.74478 1.000 17.54424 ? 17  VAL B N   1 
ATOM   1226 C CA  . VAL B 1 17  ? 38.06704 17.15057  -14.01405 1.000 17.74230 ? 17  VAL B CA  1 
ATOM   1227 C C   . VAL B 1 17  ? 37.84723 17.33181  -12.51435 1.000 17.87435 ? 17  VAL B C   1 
ATOM   1228 O O   . VAL B 1 17  ? 37.56416 18.44221  -12.04546 1.000 17.15411 ? 17  VAL B O   1 
ATOM   1229 C CB  . VAL B 1 17  ? 39.45116 17.65471  -14.46840 1.000 17.77570 ? 17  VAL B CB  1 
ATOM   1230 C CG1 . VAL B 1 17  ? 39.58388 19.17735  -14.34596 1.000 19.80986 ? 17  VAL B CG1 1 
ATOM   1231 C CG2 . VAL B 1 17  ? 40.56125 16.92871  -13.71749 1.000 18.63891 ? 17  VAL B CG2 1 
ATOM   1232 N N   . SER B 1 18  ? 37.94699 16.23543  -11.75878 1.000 16.57499 ? 18  SER B N   1 
ATOM   1233 C CA  . SER B 1 18  ? 37.78549 16.28136  -10.30988 1.000 15.85612 ? 18  SER B CA  1 
ATOM   1234 C C   . SER B 1 18  ? 38.86152 15.42810  -9.64704  1.000 17.22384 ? 18  SER B C   1 
ATOM   1235 O O   . SER B 1 18  ? 39.54885 14.63147  -10.29817 1.000 16.64720 ? 18  SER B O   1 
ATOM   1236 C CB  . SER B 1 18  ? 36.40086 15.79473  -9.86928  1.000 18.76226 ? 18  SER B CB  1 
ATOM   1237 O OG  . SER B 1 18  ? 36.19191 14.44644  -10.26247 1.000 19.01938 ? 18  SER B OG  1 
ATOM   1238 N N   . VAL B 1 19  ? 39.00497 15.60663  -8.33444  1.000 15.57742 ? 19  VAL B N   1 
ATOM   1239 C CA  . VAL B 1 19  ? 39.85054 14.73350  -7.52381  1.000 14.39899 ? 19  VAL B CA  1 
ATOM   1240 C C   . VAL B 1 19  ? 39.05966 13.47451  -7.20379  1.000 15.22695 ? 19  VAL B C   1 
ATOM   1241 O O   . VAL B 1 19  ? 37.89514 13.55373  -6.79897  1.000 16.67614 ? 19  VAL B O   1 
ATOM   1242 C CB  . VAL B 1 19  ? 40.29249 15.44972  -6.23163  1.000 13.58089 ? 19  VAL B CB  1 
ATOM   1243 C CG1 . VAL B 1 19  ? 41.15737 14.53067  -5.37298  1.000 15.70261 ? 19  VAL B CG1 1 
ATOM   1244 C CG2 . VAL B 1 19  ? 41.08304 16.71555  -6.55168  1.000 13.86506 ? 19  VAL B CG2 1 
ATOM   1245 N N   . GLN B 1 20  ? 39.69181 12.31228  -7.37386  1.000 15.03485 ? 20  GLN B N   1 
ATOM   1246 C CA  . GLN B 1 20  ? 39.05288 11.02907  -7.10541  1.000 18.65727 ? 20  GLN B CA  1 
ATOM   1247 C C   . GLN B 1 20  ? 39.34447 10.60120  -5.67172  1.000 16.70070 ? 20  GLN B C   1 
ATOM   1248 O O   . GLN B 1 20  ? 40.50995 10.43713  -5.29755  1.000 16.98688 ? 20  GLN B O   1 
ATOM   1249 C CB  . GLN B 1 20  ? 39.55992 9.97466   -8.08521  1.000 19.70646 ? 20  GLN B CB  1 
ATOM   1250 C CG  . GLN B 1 20  ? 38.91371 8.61683   -7.86877  1.000 21.00374 ? 20  GLN B CG  1 
ATOM   1251 C CD  . GLN B 1 20  ? 39.29482 7.59917   -8.92212  1.000 26.19619 ? 20  GLN B CD  1 
ATOM   1252 O OE1 . GLN B 1 20  ? 40.17242 7.83145   -9.74694  1.000 28.94770 ? 20  GLN B OE1 1 
ATOM   1253 N NE2 . GLN B 1 20  ? 38.62565 6.45404   -8.89479  1.000 29.56518 ? 20  GLN B NE2 1 
ATOM   1254 N N   . ALA B 1 21  ? 38.29578 10.40695  -4.87692  1.000 16.26112 ? 21  ALA B N   1 
ATOM   1255 C CA  . ALA B 1 21  ? 38.47661 10.05061  -3.47475  1.000 16.62401 ? 21  ALA B CA  1 
ATOM   1256 C C   . ALA B 1 21  ? 38.80727 8.57053   -3.33080  1.000 19.29521 ? 21  ALA B C   1 
ATOM   1257 O O   . ALA B 1 21  ? 38.08646 7.71097   -3.84808  1.000 19.34031 ? 21  ALA B O   1 
ATOM   1258 C CB  . ALA B 1 21  ? 37.21677 10.36719  -2.67277  1.000 18.38845 ? 21  ALA B CB  1 
ATOM   1259 N N   . GLY B 1 22  ? 39.90132 8.27962   -2.62361  1.000 16.54335 ? 22  GLY B N   1 
ATOM   1260 C CA  . GLY B 1 22  ? 40.21570 6.94672   -2.17586  1.000 18.02811 ? 22  GLY B CA  1 
ATOM   1261 C C   . GLY B 1 22  ? 39.98450 6.78995   -0.68357  1.000 16.25468 ? 22  GLY B C   1 
ATOM   1262 O O   . GLY B 1 22  ? 39.34613 7.61630   -0.02777  1.000 17.81825 ? 22  GLY B O   1 
ATOM   1263 N N   . ASP B 1 23  ? 40.51762 5.69211   -0.14427  1.000 18.86466 ? 23  ASP B N   1 
ATOM   1264 C CA  . ASP B 1 23  ? 40.25197 5.35711   1.24741   1.000 20.55722 ? 23  ASP B CA  1 
ATOM   1265 C C   . ASP B 1 23  ? 40.75280 6.45602   2.17986   1.000 17.66550 ? 23  ASP B C   1 
ATOM   1266 O O   . ASP B 1 23  ? 41.88354 6.93143   2.04976   1.000 16.77244 ? 23  ASP B O   1 
ATOM   1267 C CB  . ASP B 1 23  ? 40.94032 4.03949   1.60207   1.000 19.84625 ? 23  ASP B CB  1 
ATOM   1268 C CG  . ASP B 1 23  ? 40.21778 2.83009   1.05150   1.000 29.82143 ? 23  ASP B CG  1 
ATOM   1269 O OD1 . ASP B 1 23  ? 39.08994 2.98577   0.53677   1.000 27.95765 ? 23  ASP B OD1 1 
ATOM   1270 O OD2 . ASP B 1 23  ? 40.78607 1.72269   1.15464   1.000 30.47998 ? 23  ASP B OD2 1 
ATOM   1271 N N   . GLY B 1 24  ? 39.91298 6.83315   3.13827   1.000 17.30747 ? 24  GLY B N   1 
ATOM   1272 C CA  . GLY B 1 24  ? 40.24682 7.85703   4.10229   1.000 15.89800 ? 24  GLY B CA  1 
ATOM   1273 C C   . GLY B 1 24  ? 40.01559 9.27287   3.63101   1.000 15.03533 ? 24  GLY B C   1 
ATOM   1274 O O   . GLY B 1 24  ? 40.32271 10.20890  4.37965   1.000 14.77038 ? 24  GLY B O   1 
ATOM   1275 N N   . ILE B 1 25  ? 39.50062 9.46258   2.41047   1.000 14.73575 ? 25  ILE B N   1 
ATOM   1276 C CA  . ILE B 1 25  ? 39.40731 10.78250  1.78781   1.000 12.54289 ? 25  ILE B CA  1 
ATOM   1277 C C   . ILE B 1 25  ? 37.97202 11.01898  1.33350   1.000 17.07877 ? 25  ILE B C   1 
ATOM   1278 O O   . ILE B 1 25  ? 37.32937 10.11812  0.78289   1.000 16.41466 ? 25  ILE B O   1 
ATOM   1279 C CB  . ILE B 1 25  ? 40.38435 10.92881  0.59530   1.000 13.96608 ? 25  ILE B CB  1 
ATOM   1280 C CG1 . ILE B 1 25  ? 41.84816 10.97962  1.07360   1.000 12.78479 ? 25  ILE B CG1 1 
ATOM   1281 C CG2 . ILE B 1 25  ? 40.06603 12.18688  -0.23585  1.000 15.05552 ? 25  ILE B CG2 1 
ATOM   1282 C CD1 . ILE B 1 25  ? 42.22120 12.22405  1.91307   1.000 14.62817 ? 25  ILE B CD1 1 
ATOM   1283 N N   . SER B 1 26  ? 37.47975 12.23756  1.55281   1.000 14.27077 ? 26  SER B N   1 
ATOM   1284 C CA  . SER B 1 26  ? 36.22887 12.71176  0.97680   1.000 14.67945 ? 26  SER B CA  1 
ATOM   1285 C C   . SER B 1 26  ? 36.52996 13.84924  0.00954   1.000 14.49578 ? 26  SER B C   1 
ATOM   1286 O O   . SER B 1 26  ? 37.42803 14.65882  0.26286   1.000 15.99085 ? 26  SER B O   1 
ATOM   1287 C CB  . SER B 1 26  ? 35.31562 13.23986  2.07912   1.000 17.74440 ? 26  SER B CB  1 
ATOM   1288 O OG  . SER B 1 26  ? 34.16554 13.85440  1.52386   1.000 26.82331 ? 26  SER B OG  1 
ATOM   1289 N N   . VAL B 1 27  ? 35.78749 13.91794  -1.09504  1.000 15.41907 ? 27  VAL B N   1 
ATOM   1290 C CA  . VAL B 1 27  ? 35.94332 15.00239  -2.06109  1.000 15.06480 ? 27  VAL B CA  1 
ATOM   1291 C C   . VAL B 1 27  ? 34.58429 15.65096  -2.31151  1.000 15.51610 ? 27  VAL B C   1 
ATOM   1292 O O   . VAL B 1 27  ? 33.61599 14.96359  -2.66519  1.000 17.18256 ? 27  VAL B O   1 
ATOM   1293 C CB  . VAL B 1 27  ? 36.58745 14.51389  -3.37193  1.000 14.26737 ? 27  VAL B CB  1 
ATOM   1294 C CG1 . VAL B 1 27  ? 36.63292 15.64726  -4.38950  1.000 17.43936 ? 27  VAL B CG1 1 
ATOM   1295 C CG2 . VAL B 1 27  ? 38.01299 13.96347  -3.11093  1.000 14.53271 ? 27  VAL B CG2 1 
ATOM   1296 N N   . ALA B 1 28  ? 34.51812 16.97214  -2.13118  1.000 15.49683 ? 28  ALA B N   1 
ATOM   1297 C CA  . ALA B 1 28  ? 33.26419 17.71166  -2.26532  1.000 16.45870 ? 28  ALA B CA  1 
ATOM   1298 C C   . ALA B 1 28  ? 33.57399 19.13606  -2.71717  1.000 15.60235 ? 28  ALA B C   1 
ATOM   1299 O O   . ALA B 1 28  ? 34.73233 19.50175  -2.94065  1.000 15.64366 ? 28  ALA B O   1 
ATOM   1300 C CB  . ALA B 1 28  ? 32.48097 17.68455  -0.95352  1.000 17.38078 ? 28  ALA B CB  1 
ATOM   1301 N N   . GLY B 1 29  ? 32.52087 19.94854  -2.87524  1.000 17.19287 ? 29  GLY B N   1 
ATOM   1302 C CA  . GLY B 1 29  ? 32.75193 21.35324  -3.17886  1.000 16.23795 ? 29  GLY B CA  1 
ATOM   1303 C C   . GLY B 1 29  ? 33.43124 22.10700  -2.05892  1.000 17.58660 ? 29  GLY B C   1 
ATOM   1304 O O   . GLY B 1 29  ? 33.93471 23.21522  -2.27787  1.000 18.36557 ? 29  GLY B O   1 
ATOM   1305 N N   . THR B 1 30  ? 33.43580 21.53957  -0.85768  1.000 17.10275 ? 30  THR B N   1 
ATOM   1306 C CA  . THR B 1 30  ? 34.17372 22.09652  0.26083   1.000 18.75869 ? 30  THR B CA  1 
ATOM   1307 C C   . THR B 1 30  ? 35.64187 21.67656  0.26803   1.000 17.99975 ? 30  THR B C   1 
ATOM   1308 O O   . THR B 1 30  ? 36.36598 22.04616  1.20130   1.000 19.15570 ? 30  THR B O   1 
ATOM   1309 C CB  . THR B 1 30  ? 33.47379 21.69847  1.56404   1.000 16.77437 ? 30  THR B CB  1 
ATOM   1310 O OG1 . THR B 1 30  ? 33.14486 20.30037  1.52241   1.000 19.95261 ? 30  THR B OG1 1 
ATOM   1311 C CG2 . THR B 1 30  ? 32.18282 22.52022  1.74230   1.000 23.88292 ? 30  THR B CG2 1 
ATOM   1312 N N   . GLY B 1 31  ? 36.09489 20.92242  -0.73218  1.000 16.80489 ? 31  GLY B N   1 
ATOM   1313 C CA  . GLY B 1 31  ? 37.49825 20.57951  -0.89354  1.000 15.47538 ? 31  GLY B CA  1 
ATOM   1314 C C   . GLY B 1 31  ? 37.75872 19.09710  -0.66177  1.000 14.23125 ? 31  GLY B C   1 
ATOM   1315 O O   . GLY B 1 31  ? 36.85353 18.29814  -0.41523  1.000 16.28728 ? 31  GLY B O   1 
ATOM   1316 N N   . VAL B 1 32  ? 39.04145 18.74835  -0.74342  1.000 13.41901 ? 32  VAL B N   1 
ATOM   1317 C CA  . VAL B 1 32  ? 39.51833 17.42245  -0.36003  1.000 12.58812 ? 32  VAL B CA  1 
ATOM   1318 C C   . VAL B 1 32  ? 39.67236 17.39212  1.15495   1.000 12.99594 ? 32  VAL B C   1 
ATOM   1319 O O   . VAL B 1 32  ? 40.33815 18.25773  1.73791   1.000 13.62777 ? 32  VAL B O   1 
ATOM   1320 C CB  . VAL B 1 32  ? 40.85106 17.11449  -1.06017  1.000 11.96456 ? 32  VAL B CB  1 
ATOM   1321 C CG1 . VAL B 1 32  ? 41.36796 15.71534  -0.66337  1.000 13.36023 ? 32  VAL B CG1 1 
ATOM   1322 C CG2 . VAL B 1 32  ? 40.70861 17.23271  -2.58308  1.000 14.89248 ? 32  VAL B CG2 1 
ATOM   1323 N N   . ALA B 1 33  ? 39.04966 16.40617  1.80350   1.000 13.58427 ? 33  ALA B N   1 
ATOM   1324 C CA  . ALA B 1 33  ? 39.03385 16.33069  3.26037   1.000 14.46586 ? 33  ALA B CA  1 
ATOM   1325 C C   . ALA B 1 33  ? 39.35943 14.91318  3.71309   1.000 14.12975 ? 33  ALA B C   1 
ATOM   1326 O O   . ALA B 1 33  ? 39.13834 13.94797  2.97873   1.000 14.19802 ? 33  ALA B O   1 
ATOM   1327 C CB  . ALA B 1 33  ? 37.63940 16.72739  3.82047   1.000 15.29470 ? 33  ALA B CB  1 
ATOM   1328 N N   . VAL B 1 34  ? 39.88812 14.79326  4.93112   1.000 13.80500 ? 34  VAL B N   1 
ATOM   1329 C CA  . VAL B 1 34  ? 40.03967 13.48065  5.56347   1.000 13.43814 ? 34  VAL B CA  1 
ATOM   1330 C C   . VAL B 1 34  ? 38.68395 13.00199  6.07045   1.000 14.59746 ? 34  VAL B C   1 
ATOM   1331 O O   . VAL B 1 34  ? 37.93196 13.76294  6.69966   1.000 16.38153 ? 34  VAL B O   1 
ATOM   1332 C CB  . VAL B 1 34  ? 41.07168 13.54064  6.70054   1.000 14.62897 ? 34  VAL B CB  1 
ATOM   1333 C CG1 . VAL B 1 34  ? 41.01789 12.24809  7.53802   1.000 14.35496 ? 34  VAL B CG1 1 
ATOM   1334 C CG2 . VAL B 1 34  ? 42.45329 13.75936  6.12986   1.000 14.57354 ? 34  VAL B CG2 1 
ATOM   1335 N N   . LYS B 1 35  ? 38.36409 11.73791  5.78856   1.000 13.74562 ? 35  LYS B N   1 
ATOM   1336 C CA  . LYS B 1 35  ? 37.15260 11.08645  6.27808   1.000 16.25041 ? 35  LYS B CA  1 
ATOM   1337 C C   . LYS B 1 35  ? 37.53027 10.17979  7.44352   1.000 17.92674 ? 35  LYS B C   1 
ATOM   1338 O O   . LYS B 1 35  ? 38.33499 9.25668   7.26988   1.000 17.80100 ? 35  LYS B O   1 
ATOM   1339 C CB  . LYS B 1 35  ? 36.52624 10.25073  5.16260   1.000 17.45998 ? 35  LYS B CB  1 
ATOM   1340 C CG  . LYS B 1 35  ? 35.26703 9.51836   5.56559   1.000 19.96544 ? 35  LYS B CG  1 
ATOM   1341 C CD  . LYS B 1 35  ? 34.83258 8.55985   4.46332   1.000 24.64399 ? 35  LYS B CD  1 
ATOM   1342 C CE  . LYS B 1 35  ? 33.37116 8.15625   4.62175   1.000 30.32475 ? 35  LYS B CE  1 
ATOM   1343 N NZ  . LYS B 1 35  ? 32.98054 7.09597   3.64590   1.000 36.83086 ? 35  LYS B NZ  1 
ATOM   1344 N N   . VAL B 1 36  ? 36.93557 10.42429  8.61853   1.000 17.37495 ? 36  VAL B N   1 
ATOM   1345 C CA  . VAL B 1 36  ? 37.15567 9.57877   9.79117   1.000 17.68173 ? 36  VAL B CA  1 
ATOM   1346 C C   . VAL B 1 36  ? 35.97435 8.63227   9.95307   1.000 18.47869 ? 36  VAL B C   1 
ATOM   1347 O O   . VAL B 1 36  ? 34.81554 9.02409   9.74852   1.000 20.52985 ? 36  VAL B O   1 
ATOM   1348 C CB  . VAL B 1 36  ? 37.41071 10.39793  11.07327  1.000 20.18163 ? 36  VAL B CB  1 
ATOM   1349 C CG1 . VAL B 1 36  ? 38.67241 11.22792  10.92668  1.000 20.60869 ? 36  VAL B CG1 1 
ATOM   1350 C CG2 . VAL B 1 36  ? 36.23783 11.29367  11.41627  1.000 20.11665 ? 36  VAL B CG2 1 
ATOM   1351 N N   . GLU B 1 37  ? 36.26702 7.38374   10.32170  1.000 19.66206 ? 37  GLU B N   1 
ATOM   1352 C CA  . GLU B 1 37  ? 35.22448 6.38811   10.53843  1.000 21.45319 ? 37  GLU B CA  1 
ATOM   1353 C C   . GLU B 1 37  ? 34.59028 6.60702   11.90465  1.000 24.55968 ? 37  GLU B C   1 
ATOM   1354 O O   . GLU B 1 37  ? 35.29292 6.77109   12.90734  1.000 23.30404 ? 37  GLU B O   1 
ATOM   1355 C CB  . GLU B 1 37  ? 35.79720 4.97422   10.45187  1.000 19.82910 ? 37  GLU B CB  1 
ATOM   1356 C CG  . GLU B 1 37  ? 34.74024 3.89001   10.75062  1.000 21.99722 ? 37  GLU B CG  1 
ATOM   1357 C CD  . GLU B 1 37  ? 35.18743 2.48898   10.39289  1.000 27.99233 ? 37  GLU B CD  1 
ATOM   1358 O OE1 . GLU B 1 37  ? 36.38928 2.27910   10.13282  1.000 27.62855 ? 37  GLU B OE1 1 
ATOM   1359 O OE2 . GLU B 1 37  ? 34.31302 1.58703   10.35236  1.000 29.02960 ? 37  GLU B OE2 1 
ATOM   1360 N N   . ALA B 1 38  ? 33.25896 6.61941   11.94396  1.000 23.30120 ? 38  ALA B N   1 
ATOM   1361 C CA  . ALA B 1 38  ? 32.56592 6.77673   13.21251  1.000 23.00868 ? 38  ALA B CA  1 
ATOM   1362 C C   . ALA B 1 38  ? 32.91728 5.62940   14.14814  1.000 22.18523 ? 38  ALA B C   1 
ATOM   1363 O O   . ALA B 1 38  ? 33.09953 4.48820   13.71634  1.000 26.40879 ? 38  ALA B O   1 
ATOM   1364 C CB  . ALA B 1 38  ? 31.05370 6.78968   12.98191  1.000 26.76617 ? 38  ALA B CB  1 
ATOM   1365 N N   . SER B 1 39  ? 33.01570 5.94564   15.43577  1.000 24.21871 ? 39  SER B N   1 
ATOM   1366 C CA  . SER B 1 39  ? 33.27167 5.00966   16.52770  1.000 26.33408 ? 39  SER B CA  1 
ATOM   1367 C C   . SER B 1 39  ? 34.72319 4.54895   16.59783  1.000 23.78919 ? 39  SER B C   1 
ATOM   1368 O O   . SER B 1 39  ? 35.03412 3.71232   17.45111  1.000 24.71354 ? 39  SER B O   1 
ATOM   1369 C CB  . SER B 1 39  ? 32.37403 3.76173   16.51010  1.000 29.89588 ? 39  SER B CB  1 
ATOM   1370 O OG  . SER B 1 39  ? 32.83572 2.85537   15.52020  1.000 35.17206 ? 39  SER B OG  1 
ATOM   1371 N N   . LYS B 1 40  ? 35.61953 5.04251   15.74026  1.000 22.02165 ? 40  LYS B N   1 
ATOM   1372 C CA  . LYS B 1 40  ? 37.02032 4.63949   15.78945  1.000 18.89779 ? 40  LYS B CA  1 
ATOM   1373 C C   . LYS B 1 40  ? 37.93136 5.67643   16.43849  1.000 17.61113 ? 40  LYS B C   1 
ATOM   1374 O O   . LYS B 1 40  ? 39.16032 5.56855   16.31767  1.000 17.00720 ? 40  LYS B O   1 
ATOM   1375 C CB  . LYS B 1 40  ? 37.54017 4.24191   14.40678  1.000 20.64663 ? 40  LYS B CB  1 
ATOM   1376 C CG  . LYS B 1 40  ? 36.68620 3.20799   13.70263  1.000 25.86131 ? 40  LYS B CG  1 
ATOM   1377 C CD  . LYS B 1 40  ? 36.74122 1.88900   14.44560  1.000 27.31515 ? 40  LYS B CD  1 
ATOM   1378 C CE  . LYS B 1 40  ? 36.51934 0.70855   13.51623  1.000 29.39550 ? 40  LYS B CE  1 
ATOM   1379 N NZ  . LYS B 1 40  ? 36.75907 -0.56974  14.25097  1.000 29.57240 ? 40  LYS B NZ  1 
ATOM   1380 N N   . GLY B 1 41  ? 37.37134 6.67532   17.11603  1.000 19.19344 ? 41  GLY B N   1 
ATOM   1381 C CA  . GLY B 1 41  ? 38.14930 7.51690   18.00037  1.000 17.47069 ? 41  GLY B CA  1 
ATOM   1382 C C   . GLY B 1 41  ? 38.74422 8.78200   17.40957  1.000 16.45099 ? 41  GLY B C   1 
ATOM   1383 O O   . GLY B 1 41  ? 39.40119 9.52325   18.14322  1.000 16.34093 ? 41  GLY B O   1 
ATOM   1384 N N   . LEU B 1 42  ? 38.54095 9.06225   16.12586  1.000 16.75304 ? 42  LEU B N   1 
ATOM   1385 C CA  . LEU B 1 42  ? 39.09214 10.27624  15.53240  1.000 15.60516 ? 42  LEU B CA  1 
ATOM   1386 C C   . LEU B 1 42  ? 38.00858 11.30231  15.22936  1.000 14.49010 ? 42  LEU B C   1 
ATOM   1387 O O   . LEU B 1 42  ? 36.82456 10.98497  15.11460  1.000 16.79237 ? 42  LEU B O   1 
ATOM   1388 C CB  . LEU B 1 42  ? 39.89298 9.99119   14.25346  1.000 16.04152 ? 42  LEU B CB  1 
ATOM   1389 C CG  . LEU B 1 42  ? 40.98453 8.92588   14.41188  1.000 17.50992 ? 42  LEU B CG  1 
ATOM   1390 C CD1 . LEU B 1 42  ? 41.69052 8.70513   13.08880  1.000 17.04825 ? 42  LEU B CD1 1 
ATOM   1391 C CD2 . LEU B 1 42  ? 41.96453 9.31383   15.50414  1.000 18.07191 ? 42  LEU B CD2 1 
ATOM   1392 N N   . GLN B 1 43  ? 38.45458 12.54952  15.08282  1.000 15.69544 ? 43  GLN B N   1 
ATOM   1393 C CA  . GLN B 1 43  ? 37.61145 13.64424  14.62727  1.000 15.25488 ? 43  GLN B CA  1 
ATOM   1394 C C   . GLN B 1 43  ? 38.40083 14.45146  13.60901  1.000 15.82109 ? 43  GLN B C   1 
ATOM   1395 O O   . GLN B 1 43  ? 39.63012 14.33991  13.51188  1.000 14.28986 ? 43  GLN B O   1 
ATOM   1396 C CB  . GLN B 1 43  ? 37.22703 14.57684  15.78567  1.000 14.23503 ? 43  GLN B CB  1 
ATOM   1397 C CG  . GLN B 1 43  ? 38.44893 15.15856  16.50164  1.000 15.37895 ? 43  GLN B CG  1 
ATOM   1398 C CD  . GLN B 1 43  ? 38.08438 16.12735  17.59308  1.000 15.11847 ? 43  GLN B CD  1 
ATOM   1399 O OE1 . GLN B 1 43  ? 37.27716 15.80634  18.47262  1.000 18.53952 ? 43  GLN B OE1 1 
ATOM   1400 N NE2 . GLN B 1 43  ? 38.68174 17.31665  17.56624  1.000 17.29618 ? 43  GLN B NE2 1 
ATOM   1401 N N   . VAL B 1 44  ? 37.68812 15.27358  12.84737  1.000 14.59681 ? 44  VAL B N   1 
ATOM   1402 C CA  . VAL B 1 44  ? 38.32729 16.20778  11.92752  1.000 13.63907 ? 44  VAL B CA  1 
ATOM   1403 C C   . VAL B 1 44  ? 37.56556 17.52299  11.95393  1.000 14.99397 ? 44  VAL B C   1 
ATOM   1404 O O   . VAL B 1 44  ? 36.33430 17.54028  11.85041  1.000 17.58315 ? 44  VAL B O   1 
ATOM   1405 C CB  . VAL B 1 44  ? 38.50367 15.65035  10.49618  1.000 17.14647 ? 44  VAL B CB  1 
ATOM   1406 C CG1 . VAL B 1 44  ? 37.16979 15.41353  9.79876   1.000 18.22555 ? 44  VAL B CG1 1 
ATOM   1407 C CG2 . VAL B 1 44  ? 39.42978 16.56758  9.68393   1.000 16.84648 ? 44  VAL B CG2 1 
ATOM   1408 N N   . THR B 1 45  ? 38.29816 18.61753  12.13970  1.000 15.01270 ? 45  THR B N   1 
ATOM   1409 C CA  . THR B 1 45  ? 37.71537 19.95211  12.08279  1.000 15.69786 ? 45  THR B CA  1 
ATOM   1410 C C   . THR B 1 45  ? 38.57008 20.81077  11.16219  1.000 16.66710 ? 45  THR B C   1 
ATOM   1411 O O   . THR B 1 45  ? 39.50185 20.30664  10.53144  1.000 15.98935 ? 45  THR B O   1 
ATOM   1412 C CB  . THR B 1 45  ? 37.68937 20.59598  13.46852  1.000 16.24857 ? 45  THR B CB  1 
ATOM   1413 O OG1 . THR B 1 45  ? 39.03025 20.93597  13.85850  1.000 17.36309 ? 45  THR B OG1 1 
ATOM   1414 C CG2 . THR B 1 45  ? 37.07592 19.66079  14.51482  1.000 15.76135 ? 45  THR B CG2 1 
ATOM   1415 N N   . SER B 1 46  ? 38.28331 22.11112  11.08557  1.000 15.43228 ? 46  SER B N   1 
ATOM   1416 C CA  . SER B 1 46  ? 39.14611 22.99912  10.30717  1.000 16.17656 ? 46  SER B CA  1 
ATOM   1417 C C   . SER B 1 46  ? 40.57139 23.06950  10.85839  1.000 16.26757 ? 46  SER B C   1 
ATOM   1418 O O   . SER B 1 46  ? 41.48363 23.48011  10.12844  1.000 17.55519 ? 46  SER B O   1 
ATOM   1419 C CB  . SER B 1 46  ? 38.50602 24.39493  10.20253  1.000 16.69452 ? 46  SER B CB  1 
ATOM   1420 O OG  . SER B 1 46  ? 38.45788 25.01081  11.47118  1.000 17.14377 ? 46  SER B OG  1 
ATOM   1421 N N   . ASN B 1 47  ? 40.78776 22.67357  12.11739  1.000 15.82370 ? 47  ASN B N   1 
ATOM   1422 C CA  . ASN B 1 47  ? 42.12490 22.60157  12.70848  1.000 16.34245 ? 47  ASN B CA  1 
ATOM   1423 C C   . ASN B 1 47  ? 42.88242 21.34052  12.29810  1.000 17.13925 ? 47  ASN B C   1 
ATOM   1424 O O   . ASN B 1 47  ? 44.10173 21.28031  12.49561  1.000 19.51693 ? 47  ASN B O   1 
ATOM   1425 C CB  . ASN B 1 47  ? 42.00699 22.61544  14.23730  1.000 21.44934 ? 47  ASN B CB  1 
ATOM   1426 C CG  . ASN B 1 47  ? 42.04001 24.01854  14.83443  1.000 23.98703 ? 47  ASN B CG  1 
ATOM   1427 O OD1 . ASN B 1 47  ? 42.13808 25.02188  14.12334  1.000 24.52106 ? 47  ASN B OD1 1 
ATOM   1428 N ND2 . ASN B 1 47  ? 41.95083 24.08628  16.16166  1.000 26.85472 ? 47  ASN B ND2 1 
ATOM   1429 N N   . GLY B 1 48  ? 42.19866 20.32337  11.76642  1.000 15.59126 ? 48  GLY B N   1 
ATOM   1430 C CA  . GLY B 1 48  ? 42.86234 19.11430  11.31767  1.000 14.89953 ? 48  GLY B CA  1 
ATOM   1431 C C   . GLY B 1 48  ? 42.27084 17.86489  11.94573  1.000 15.00017 ? 48  GLY B C   1 
ATOM   1432 O O   . GLY B 1 48  ? 41.24697 17.89934  12.63542  1.000 14.71490 ? 48  GLY B O   1 
ATOM   1433 N N   . VAL B 1 49  ? 42.93181 16.72573  11.69076  1.000 14.38283 ? 49  VAL B N   1 
ATOM   1434 C CA  . VAL B 1 49  ? 42.54032 15.42952  12.24104  1.000 15.73414 ? 49  VAL B CA  1 
ATOM   1435 C C   . VAL B 1 49  ? 43.16046 15.26292  13.61971  1.000 14.90176 ? 49  VAL B C   1 
ATOM   1436 O O   . VAL B 1 49  ? 44.32817 15.61233  13.83130  1.000 15.20548 ? 49  VAL B O   1 
ATOM   1437 C CB  . VAL B 1 49  ? 42.99945 14.29079  11.31336  1.000 17.54936 ? 49  VAL B CB  1 
ATOM   1438 C CG1 . VAL B 1 49  ? 42.34713 12.96291  11.71507  1.000 14.36944 ? 49  VAL B CG1 1 
ATOM   1439 C CG2 . VAL B 1 49  ? 42.71787 14.61778  9.86177   1.000 20.05323 ? 49  VAL B CG2 1 
ATOM   1440 N N   . GLY B 1 50  ? 42.38413 14.71580  14.55338  1.000 14.74649 ? 50  GLY B N   1 
ATOM   1441 C CA  . GLY B 1 50  ? 42.88517 14.43259  15.89095  1.000 15.57583 ? 50  GLY B CA  1 
ATOM   1442 C C   . GLY B 1 50  ? 42.08134 13.34943  16.58513  1.000 15.23710 ? 50  GLY B C   1 
ATOM   1443 O O   . GLY B 1 50  ? 41.06486 12.86659  16.08211  1.000 14.71832 ? 50  GLY B O   1 
ATOM   1444 N N   . LEU B 1 51  ? 42.55988 12.96273  17.76709  1.000 13.75808 ? 51  LEU B N   1 
ATOM   1445 C CA  . LEU B 1 51  ? 41.76020 12.11585  18.63697  1.000 15.86530 ? 51  LEU B CA  1 
ATOM   1446 C C   . LEU B 1 51  ? 40.55960 12.90914  19.13145  1.000 17.89295 ? 51  LEU B C   1 
ATOM   1447 O O   . LEU B 1 51  ? 40.66440 14.10328  19.42623  1.000 16.70124 ? 51  LEU B O   1 
ATOM   1448 C CB  . LEU B 1 51  ? 42.58019 11.68276  19.84089  1.000 16.43503 ? 51  LEU B CB  1 
ATOM   1449 C CG  . LEU B 1 51  ? 43.74028 10.74782  19.50263  1.000 15.44316 ? 51  LEU B CG  1 
ATOM   1450 C CD1 . LEU B 1 51  ? 44.72148 10.65002  20.65496  1.000 21.02199 ? 51  LEU B CD1 1 
ATOM   1451 C CD2 . LEU B 1 51  ? 43.19582 9.37798   19.13251  1.000 17.65531 ? 51  LEU B CD2 1 
ATOM   1452 N N   . ASN B 1 52  ? 39.41048 12.24485  19.21194  1.000 15.46839 ? 52  ASN B N   1 
ATOM   1453 C CA  . ASN B 1 52  ? 38.24522 12.86684  19.82414  1.000 16.41042 ? 52  ASN B CA  1 
ATOM   1454 C C   . ASN B 1 52  ? 38.29730 12.67077  21.33854  1.000 20.28721 ? 52  ASN B C   1 
ATOM   1455 O O   . ASN B 1 52  ? 39.19420 12.01150  21.86934  1.000 20.64417 ? 52  ASN B O   1 
ATOM   1456 C CB  . ASN B 1 52  ? 36.95123 12.38793  19.15923  1.000 19.09826 ? 52  ASN B CB  1 
ATOM   1457 C CG  . ASN B 1 52  ? 36.60737 10.93428  19.46782  1.000 18.34340 ? 52  ASN B CG  1 
ATOM   1458 O OD1 . ASN B 1 52  ? 36.89779 10.42144  20.54235  1.000 19.90796 ? 52  ASN B OD1 1 
ATOM   1459 N ND2 . ASN B 1 52  ? 35.96756 10.26943  18.50921  1.000 17.06199 ? 52  ASN B ND2 1 
ATOM   1460 N N   . ASN B 1 53  ? 37.30255 13.21106  22.04849  1.000 17.81302 ? 53  ASN B N   1 
ATOM   1461 C CA  . ASN B 1 53  ? 37.34019 13.20795  23.50426  1.000 18.75996 ? 53  ASN B CA  1 
ATOM   1462 C C   . ASN B 1 53  ? 36.86771 11.90325  24.13270  1.000 18.24940 ? 53  ASN B C   1 
ATOM   1463 O O   . ASN B 1 53  ? 36.88326 11.80644  25.36529  1.000 22.02663 ? 53  ASN B O   1 
ATOM   1464 C CB  . ASN B 1 53  ? 36.53351 14.37824  24.08190  1.000 21.27109 ? 53  ASN B CB  1 
ATOM   1465 C CG  . ASN B 1 53  ? 37.39047 15.59637  24.34702  1.000 31.48567 ? 53  ASN B CG  1 
ATOM   1466 O OD1 . ASN B 1 53  ? 38.57033 15.47509  24.68075  1.000 35.72117 ? 53  ASN B OD1 1 
ATOM   1467 N ND2 . ASN B 1 53  ? 36.80071 16.78337  24.21319  1.000 32.79868 ? 53  ASN B ND2 1 
ATOM   1468 N N   . THR B 1 54  ? 36.46190 10.90566  23.34345  1.000 18.25236 ? 54  THR B N   1 
ATOM   1469 C CA  . THR B 1 54  ? 36.11322 9.59964   23.89584  1.000 18.06946 ? 54  THR B CA  1 
ATOM   1470 C C   . THR B 1 54  ? 36.95542 8.47029   23.31543  1.000 17.73592 ? 54  THR B C   1 
ATOM   1471 O O   . THR B 1 54  ? 36.62114 7.29478   23.51344  1.000 17.96548 ? 54  THR B O   1 
ATOM   1472 C CB  . THR B 1 54  ? 34.61900 9.29935   23.72529  1.000 20.71818 ? 54  THR B CB  1 
ATOM   1473 O OG1 . THR B 1 54  ? 34.26879 9.36035   22.33765  1.000 21.95425 ? 54  THR B OG1 1 
ATOM   1474 C CG2 . THR B 1 54  ? 33.78449 10.29167  24.51128  1.000 24.31386 ? 54  THR B CG2 1 
ATOM   1475 N N   . ALA B 1 55  ? 38.04419 8.79360   22.60357  1.000 16.85806 ? 55  ALA B N   1 
ATOM   1476 C CA  . ALA B 1 55  ? 38.95002 7.75096   22.12227  1.000 15.45021 ? 55  ALA B CA  1 
ATOM   1477 C C   . ALA B 1 55  ? 39.43182 6.86387   23.26021  1.000 14.18363 ? 55  ALA B C   1 
ATOM   1478 O O   . ALA B 1 55  ? 39.66586 5.66659   23.05914  1.000 14.95606 ? 55  ALA B O   1 
ATOM   1479 C CB  . ALA B 1 55  ? 40.15413 8.39529   21.42181  1.000 16.16602 ? 55  ALA B CB  1 
ATOM   1480 N N   . TRP B 1 56  ? 39.57960 7.43413   24.45829  1.000 14.77027 ? 56  TRP B N   1 
ATOM   1481 C CA  . TRP B 1 56  ? 40.05398 6.66755   25.60535  1.000 14.67707 ? 56  TRP B CA  1 
ATOM   1482 C C   . TRP B 1 56  ? 39.13386 5.49908   25.94404  1.000 15.02172 ? 56  TRP B C   1 
ATOM   1483 O O   . TRP B 1 56  ? 39.59750 4.48487   26.47749  1.000 15.65056 ? 56  TRP B O   1 
ATOM   1484 C CB  . TRP B 1 56  ? 40.23341 7.59584   26.80919  1.000 16.14035 ? 56  TRP B CB  1 
ATOM   1485 C CG  . TRP B 1 56  ? 38.94855 8.20294   27.32112  1.000 14.74811 ? 56  TRP B CG  1 
ATOM   1486 C CD1 . TRP B 1 56  ? 38.40830 9.41008   26.96735  1.000 16.79372 ? 56  TRP B CD1 1 
ATOM   1487 C CD2 . TRP B 1 56  ? 38.05534 7.63132   28.28484  1.000 14.33794 ? 56  TRP B CD2 1 
ATOM   1488 N NE1 . TRP B 1 56  ? 37.23196 9.62878   27.65632  1.000 17.08145 ? 56  TRP B NE1 1 
ATOM   1489 C CE2 . TRP B 1 56  ? 36.99396 8.54813   28.46895  1.000 15.91515 ? 56  TRP B CE2 1 
ATOM   1490 C CE3 . TRP B 1 56  ? 38.05703 6.43531   29.02016  1.000 16.30567 ? 56  TRP B CE3 1 
ATOM   1491 C CZ2 . TRP B 1 56  ? 35.93979 8.30120   29.35431  1.000 16.70167 ? 56  TRP B CZ2 1 
ATOM   1492 C CZ3 . TRP B 1 56  ? 37.00357 6.19085   29.89585  1.000 17.65147 ? 56  TRP B CZ3 1 
ATOM   1493 C CH2 . TRP B 1 56  ? 35.96300 7.12169   30.05091  1.000 18.33512 ? 56  TRP B CH2 1 
ATOM   1494 N N   . ILE B 1 57  ? 37.83744 5.60461   25.63771  1.000 16.64281 ? 57  ILE B N   1 
ATOM   1495 C CA  . ILE B 1 57  ? 36.92787 4.48962   25.89659  1.000 15.86706 ? 57  ILE B CA  1 
ATOM   1496 C C   . ILE B 1 57  ? 37.30585 3.27785   25.05055  1.000 15.13238 ? 57  ILE B C   1 
ATOM   1497 O O   . ILE B 1 57  ? 37.34518 2.14411   25.54246  1.000 15.46585 ? 57  ILE B O   1 
ATOM   1498 C CB  . ILE B 1 57  ? 35.46913 4.92456   25.66782  1.000 15.78391 ? 57  ILE B CB  1 
ATOM   1499 C CG1 . ILE B 1 57  ? 35.10925 6.03524   26.65449  1.000 17.06579 ? 57  ILE B CG1 1 
ATOM   1500 C CG2 . ILE B 1 57  ? 34.50676 3.72028   25.79621  1.000 18.00977 ? 57  ILE B CG2 1 
ATOM   1501 C CD1 . ILE B 1 57  ? 33.67197 6.55006   26.52433  1.000 16.55394 ? 57  ILE B CD1 1 
ATOM   1502 N N   . LYS B 1 58  ? 37.57744 3.49757   23.76173  1.000 16.43253 ? 58  LYS B N   1 
ATOM   1503 C CA  . LYS B 1 58  ? 38.01122 2.40756   22.88806  1.000 16.61660 ? 58  LYS B CA  1 
ATOM   1504 C C   . LYS B 1 58  ? 39.32583 1.80589   23.36659  1.000 17.22874 ? 58  LYS B C   1 
ATOM   1505 O O   . LYS B 1 58  ? 39.52157 0.58302   23.30949  1.000 16.76774 ? 58  LYS B O   1 
ATOM   1506 C CB  . LYS B 1 58  ? 38.15206 2.92798   21.45128  1.000 16.16912 ? 58  LYS B CB  1 
ATOM   1507 C CG  . LYS B 1 58  ? 38.60179 1.87252   20.44508  1.000 17.36990 ? 58  LYS B CG  1 
ATOM   1508 C CD  . LYS B 1 58  ? 38.56744 2.43027   19.02349  1.000 20.11695 ? 58  LYS B CD  1 
ATOM   1509 C CE  . LYS B 1 58  ? 39.27926 1.52320   18.03923  1.000 22.75676 ? 58  LYS B CE  1 
ATOM   1510 N NZ  . LYS B 1 58  ? 38.55315 0.22956   17.90859  1.000 24.15411 ? 58  LYS B NZ  1 
ATOM   1511 N N   . MET B 1 59  ? 40.23498 2.65316   23.85031  1.000 15.18326 ? 59  MET B N   1 
ATOM   1512 C CA  . MET B 1 59  ? 41.50903 2.16661   24.36957  1.000 15.82026 ? 59  MET B CA  1 
ATOM   1513 C C   . MET B 1 59  ? 41.31239 1.27134   25.58941  1.000 15.03187 ? 59  MET B C   1 
ATOM   1514 O O   . MET B 1 59  ? 41.92305 0.20072   25.68760  1.000 15.15771 ? 59  MET B O   1 
ATOM   1515 C CB  . MET B 1 59  ? 42.38355 3.35772   24.73250  1.000 17.47512 ? 59  MET B CB  1 
ATOM   1516 C CG  . MET B 1 59  ? 42.67396 4.24358   23.55043  1.000 23.18717 ? 59  MET B CG  1 
ATOM   1517 S SD  . MET B 1 59  ? 43.64663 3.46630   22.26105  0.639 19.27082 ? 59  MET B SD  1 
ATOM   1518 C CE  . MET B 1 59  ? 44.28715 4.93816   21.46732  1.000 29.81602 ? 59  MET B CE  1 
ATOM   1519 N N   . MET B 1 60  ? 40.47843 1.70273   26.54570  1.000 16.30622 ? 60  MET B N   1 
ATOM   1520 C CA  . MET B 1 60  ? 40.28332 0.91414   27.76314  1.000 14.36675 ? 60  MET B CA  1 
ATOM   1521 C C   . MET B 1 60  ? 39.51387 -0.37197  27.48107  1.000 15.75890 ? 60  MET B C   1 
ATOM   1522 O O   . MET B 1 60  ? 39.75300 -1.39864  28.13686  1.000 14.90734 ? 60  MET B O   1 
ATOM   1523 C CB  . MET B 1 60  ? 39.53241 1.74108   28.80798  1.000 14.91556 ? 60  MET B CB  1 
ATOM   1524 C CG  . MET B 1 60  ? 40.27792 3.00516   29.20362  1.000 17.08539 ? 60  MET B CG  1 
ATOM   1525 S SD  . MET B 1 60  ? 41.91792 2.69719   29.88632  0.932 18.09340 ? 60  MET B SD  1 
ATOM   1526 C CE  . MET B 1 60  ? 41.49159 1.79650   31.36582  1.000 18.82916 ? 60  MET B CE  1 
ATOM   1527 N N   . CYS B 1 61  ? 38.57959 -0.34440  26.52905  1.000 16.81942 ? 61  CYS B N   1 
ATOM   1528 C CA  . CYS B 1 61  ? 37.92654 -1.59013  26.13165  1.000 15.58822 ? 61  CYS B CA  1 
ATOM   1529 C C   . CYS B 1 61  ? 38.94083 -2.55945  25.54249  1.000 15.27664 ? 61  CYS B C   1 
ATOM   1530 O O   . CYS B 1 61  ? 38.89789 -3.76348  25.81733  1.000 16.56128 ? 61  CYS B O   1 
ATOM   1531 C CB  . CYS B 1 61  ? 36.79796 -1.32425  25.12913  1.000 17.13848 ? 61  CYS B CB  1 
ATOM   1532 S SG  . CYS B 1 61  ? 35.30231 -0.60113  25.85408  0.956 17.69551 ? 61  CYS B SG  1 
ATOM   1533 N N   . GLY B 1 62  ? 39.85428 -2.05077  24.71612  1.000 15.32264 ? 62  GLY B N   1 
ATOM   1534 C CA  . GLY B 1 62  ? 40.93005 -2.88772  24.20013  1.000 15.58308 ? 62  GLY B CA  1 
ATOM   1535 C C   . GLY B 1 62  ? 41.83847 -3.42368  25.28969  1.000 14.74502 ? 62  GLY B C   1 
ATOM   1536 O O   . GLY B 1 62  ? 42.19815 -4.60185  25.28731  1.000 16.22270 ? 62  GLY B O   1 
ATOM   1537 N N   . LEU B 1 63  ? 42.24418 -2.55338  26.21853  1.000 15.25272 ? 63  LEU B N   1 
ATOM   1538 C CA  . LEU B 1 63  ? 43.11807 -2.95249  27.31978  1.000 14.19043 ? 63  LEU B CA  1 
ATOM   1539 C C   . LEU B 1 63  ? 42.58006 -4.17702  28.05172  1.000 16.24515 ? 63  LEU B C   1 
ATOM   1540 O O   . LEU B 1 63  ? 43.31109 -5.14616  28.29440  1.000 15.09438 ? 63  LEU B O   1 
ATOM   1541 C CB  . LEU B 1 63  ? 43.25215 -1.77789  28.29401  1.000 15.59413 ? 63  LEU B CB  1 
ATOM   1542 C CG  . LEU B 1 63  ? 43.93827 -2.03729  29.64119  1.000 16.62093 ? 63  LEU B CG  1 
ATOM   1543 C CD1 . LEU B 1 63  ? 45.38459 -2.49976  29.44728  1.000 15.42661 ? 63  LEU B CD1 1 
ATOM   1544 C CD2 . LEU B 1 63  ? 43.85580 -0.82600  30.56889  1.000 17.11667 ? 63  LEU B CD2 1 
ATOM   1545 N N   . HIS B 1 64  ? 41.29962 -4.15252  28.41445  1.000 15.71174 ? 64  HIS B N   1 
ATOM   1546 C CA  . HIS B 1 64  ? 40.70617 -5.21154  29.21947  1.000 15.63781 ? 64  HIS B CA  1 
ATOM   1547 C C   . HIS B 1 64  ? 39.98091 -6.26604  28.39634  1.000 16.26000 ? 64  HIS B C   1 
ATOM   1548 O O   . HIS B 1 64  ? 39.45271 -7.22213  28.97497  1.000 16.01908 ? 64  HIS B O   1 
ATOM   1549 C CB  . HIS B 1 64  ? 39.77140 -4.61100  30.28062  1.000 14.39925 ? 64  HIS B CB  1 
ATOM   1550 C CG  . HIS B 1 64  ? 40.49252 -3.81333  31.31950  1.000 14.68925 ? 64  HIS B CG  1 
ATOM   1551 N ND1 . HIS B 1 64  ? 41.44588 -4.36363  32.15067  1.000 14.59653 ? 64  HIS B ND1 1 
ATOM   1552 C CD2 . HIS B 1 64  ? 40.41608 -2.50106  31.64877  1.000 15.34123 ? 64  HIS B CD2 1 
ATOM   1553 C CE1 . HIS B 1 64  ? 41.91274 -3.42360  32.95916  1.000 14.35992 ? 64  HIS B CE1 1 
ATOM   1554 N NE2 . HIS B 1 64  ? 41.30970 -2.28334  32.66969  1.000 13.01303 ? 64  HIS B NE2 1 
ATOM   1555 N N   . ASN B 1 65  ? 39.96686 -6.12944  27.07148  1.000 15.99515 ? 65  ASN B N   1 
ATOM   1556 C CA  . ASN B 1 65  ? 39.15077 -6.96645  26.19431  1.000 17.01692 ? 65  ASN B CA  1 
ATOM   1557 C C   . ASN B 1 65  ? 37.70679 -6.99611  26.66893  1.000 17.39044 ? 65  ASN B C   1 
ATOM   1558 O O   . ASN B 1 65  ? 37.08260 -8.05326  26.78038  1.000 18.01654 ? 65  ASN B O   1 
ATOM   1559 C CB  . ASN B 1 65  ? 39.72568 -8.37475  26.04091  1.000 20.62786 ? 65  ASN B CB  1 
ATOM   1560 C CG  . ASN B 1 65  ? 39.18646 -9.07988  24.81765  1.000 24.50543 ? 65  ASN B CG  1 
ATOM   1561 O OD1 . ASN B 1 65  ? 38.76451 -8.43558  23.85458  1.000 26.71830 ? 65  ASN B OD1 1 
ATOM   1562 N ND2 . ASN B 1 65  ? 39.21144 -10.40578 24.83672  1.000 28.43262 ? 65  ASN B ND2 1 
ATOM   1563 N N   . ALA B 1 66  ? 37.18055 -5.80986  26.95432  1.000 17.64233 ? 66  ALA B N   1 
ATOM   1564 C CA  . ALA B 1 66  ? 35.81944 -5.65431  27.43641  1.000 16.90299 ? 66  ALA B CA  1 
ATOM   1565 C C   . ALA B 1 66  ? 34.86799 -5.51526  26.25733  1.000 19.95566 ? 66  ALA B C   1 
ATOM   1566 O O   . ALA B 1 66  ? 35.19558 -4.88896  25.24506  1.000 20.18862 ? 66  ALA B O   1 
ATOM   1567 C CB  . ALA B 1 66  ? 35.71379 -4.41421  28.32608  1.000 14.79350 ? 66  ALA B CB  1 
ATOM   1568 N N   . THR B 1 67  ? 33.66813 -6.07183  26.40741  1.000 18.40006 ? 67  THR B N   1 
ATOM   1569 C CA  . THR B 1 67  ? 32.66438 -6.00892  25.35099  1.000 16.79916 ? 67  THR B CA  1 
ATOM   1570 C C   . THR B 1 67  ? 31.55341 -5.00478  25.62859  1.000 18.18214 ? 67  THR B C   1 
ATOM   1571 O O   . THR B 1 67  ? 30.78489 -4.69096  24.71099  1.000 19.57057 ? 67  THR B O   1 
ATOM   1572 C CB  . THR B 1 67  ? 32.08807 -7.40469  25.07271  1.000 18.51536 ? 67  THR B CB  1 
ATOM   1573 O OG1 . THR B 1 67  ? 31.70425 -8.01522  26.30977  1.000 20.59248 ? 67  THR B OG1 1 
ATOM   1574 C CG2 . THR B 1 67  ? 33.13640 -8.26634  24.38646  1.000 21.31761 ? 67  THR B CG2 1 
ATOM   1575 N N   . PHE B 1 68  ? 31.46646 -4.48684  26.85645  1.000 16.99290 ? 68  PHE B N   1 
ATOM   1576 C CA  . PHE B 1 68  ? 30.49904 -3.46033  27.21787  1.000 17.04155 ? 68  PHE B CA  1 
ATOM   1577 C C   . PHE B 1 68  ? 31.14470 -2.50051  28.20681  1.000 17.14958 ? 68  PHE B C   1 
ATOM   1578 O O   . PHE B 1 68  ? 32.12279 -2.83290  28.87947  1.000 16.72333 ? 68  PHE B O   1 
ATOM   1579 C CB  . PHE B 1 68  ? 29.21284 -4.07121  27.81490  1.000 18.29850 ? 68  PHE B CB  1 
ATOM   1580 C CG  . PHE B 1 68  ? 28.53370 -5.04090  26.88748  1.000 19.11847 ? 68  PHE B CG  1 
ATOM   1581 C CD1 . PHE B 1 68  ? 27.64736 -4.58879  25.92227  1.000 19.54805 ? 68  PHE B CD1 1 
ATOM   1582 C CD2 . PHE B 1 68  ? 28.84386 -6.39625  26.92759  1.000 17.57238 ? 68  PHE B CD2 1 
ATOM   1583 C CE1 . PHE B 1 68  ? 27.05770 -5.47525  25.04199  1.000 20.46714 ? 68  PHE B CE1 1 
ATOM   1584 C CE2 . PHE B 1 68  ? 28.25827 -7.27604  26.04529  1.000 22.86868 ? 68  PHE B CE2 1 
ATOM   1585 C CZ  . PHE B 1 68  ? 27.36740 -6.81174  25.10593  1.000 20.30950 ? 68  PHE B CZ  1 
ATOM   1586 N N   . TYR B 1 69  ? 30.59130 -1.29451  28.29171  1.000 15.80279 ? 69  TYR B N   1 
ATOM   1587 C CA  . TYR B 1 69  ? 31.13729 -0.30701  29.20805  1.000 15.90849 ? 69  TYR B CA  1 
ATOM   1588 C C   . TYR B 1 69  ? 30.02496 0.61972   29.67613  1.000 16.16608 ? 69  TYR B C   1 
ATOM   1589 O O   . TYR B 1 69  ? 28.93960 0.66819   29.09013  1.000 15.97799 ? 69  TYR B O   1 
ATOM   1590 C CB  . TYR B 1 69  ? 32.27228 0.51378   28.55886  1.000 17.38296 ? 69  TYR B CB  1 
ATOM   1591 C CG  . TYR B 1 69  ? 31.77625 1.56742   27.58773  1.000 17.45708 ? 69  TYR B CG  1 
ATOM   1592 C CD1 . TYR B 1 69  ? 31.48518 1.24404   26.26061  1.000 18.95645 ? 69  TYR B CD1 1 
ATOM   1593 C CD2 . TYR B 1 69  ? 31.58822 2.87648   27.99712  1.000 16.91477 ? 69  TYR B CD2 1 
ATOM   1594 C CE1 . TYR B 1 69  ? 31.01361 2.21147   25.37093  1.000 20.51128 ? 69  TYR B CE1 1 
ATOM   1595 C CE2 . TYR B 1 69  ? 31.10362 3.84436   27.12045  1.000 18.71292 ? 69  TYR B CE2 1 
ATOM   1596 C CZ  . TYR B 1 69  ? 30.82639 3.50280   25.81282  1.000 18.94826 ? 69  TYR B CZ  1 
ATOM   1597 O OH  . TYR B 1 69  ? 30.37538 4.45981   24.93478  1.000 21.01974 ? 69  TYR B OH  1 
ATOM   1598 N N   . VAL B 1 70  ? 30.30826 1.34815   30.75203  1.000 16.39277 ? 70  VAL B N   1 
ATOM   1599 C CA  . VAL B 1 70  ? 29.54329 2.53793   31.11586  1.000 15.12669 ? 70  VAL B CA  1 
ATOM   1600 C C   . VAL B 1 70  ? 30.53359 3.65415   31.39739  1.000 17.05237 ? 70  VAL B C   1 
ATOM   1601 O O   . VAL B 1 70  ? 31.66463 3.41472   31.82887  1.000 15.77226 ? 70  VAL B O   1 
ATOM   1602 C CB  . VAL B 1 70  ? 28.60610 2.35602   32.33810  1.000 19.34530 ? 70  VAL B CB  1 
ATOM   1603 C CG1 . VAL B 1 70  ? 27.54710 1.29581   32.08018  1.000 21.06999 ? 70  VAL B CG1 1 
ATOM   1604 C CG2 . VAL B 1 70  ? 29.40124 2.04705   33.58133  1.000 20.38179 ? 70  VAL B CG2 1 
ATOM   1605 N N   . SER B 1 71  ? 30.10733 4.88600   31.15536  1.000 18.81880 ? 71  SER B N   1 
ATOM   1606 C CA  . SER B 1 71  ? 30.92223 6.02607   31.54767  1.000 19.55389 ? 71  SER B CA  1 
ATOM   1607 C C   . SER B 1 71  ? 29.98950 7.16959   31.90337  1.000 19.31990 ? 71  SER B C   1 
ATOM   1608 O O   . SER B 1 71  ? 29.09177 7.49929   31.12351  1.000 22.74597 ? 71  SER B O   1 
ATOM   1609 C CB  . SER B 1 71  ? 31.86621 6.44448   30.41727  1.000 21.67027 ? 71  SER B CB  1 
ATOM   1610 O OG  . SER B 1 71  ? 32.70236 7.51649   30.82751  1.000 20.27801 ? 71  SER B OG  1 
ATOM   1611 N N   . ASP B 1 72  ? 30.17485 7.74046   33.08989  1.000 18.93586 ? 72  ASP B N   1 
ATOM   1612 C CA  . ASP B 1 72  ? 29.55434 9.01425   33.43230  1.000 19.57931 ? 72  ASP B CA  1 
ATOM   1613 C C   . ASP B 1 72  ? 30.60337 9.89583   34.10147  1.000 18.94757 ? 72  ASP B C   1 
ATOM   1614 O O   . ASP B 1 72  ? 31.79737 9.57966   34.11124  1.000 17.13300 ? 72  ASP B O   1 
ATOM   1615 C CB  . ASP B 1 72  ? 28.20985 8.86429   34.17157  1.000 24.22333 ? 72  ASP B CB  1 
ATOM   1616 C CG  . ASP B 1 72  ? 28.36288 8.43470   35.62118  1.000 22.80973 ? 72  ASP B CG  1 
ATOM   1617 O OD1 . ASP B 1 72  ? 29.50186 8.39652   36.13474  1.000 23.14173 ? 72  ASP B OD1 1 
ATOM   1618 O OD2 . ASP B 1 72  ? 27.31058 8.15979   36.25699  1.000 24.45626 ? 72  ASP B OD2 1 
ATOM   1619 N N   . THR B 1 73  ? 30.14461 11.00251  34.68705  1.000 20.07899 ? 73  THR B N   1 
ATOM   1620 C CA  . THR B 1 73  ? 31.05284 12.02184  35.19990  1.000 21.75658 ? 73  THR B CA  1 
ATOM   1621 C C   . THR B 1 73  ? 31.93571 11.50401  36.32572  1.000 16.84607 ? 73  THR B C   1 
ATOM   1622 O O   . THR B 1 73  ? 33.03203 12.02861  36.53831  1.000 20.44486 ? 73  THR B O   1 
ATOM   1623 C CB  . THR B 1 73  ? 30.22408 13.20833  35.69363  1.000 27.77332 ? 73  THR B CB  1 
ATOM   1624 O OG1 . THR B 1 73  ? 29.40506 13.66533  34.62021  1.000 29.74797 ? 73  THR B OG1 1 
ATOM   1625 C CG2 . THR B 1 73  ? 31.10478 14.33898  36.16457  1.000 28.16025 ? 73  THR B CG2 1 
ATOM   1626 N N   . TYR B 1 74  ? 31.48804 10.48131  37.05278  1.000 16.33248 ? 74  TYR B N   1 
ATOM   1627 C CA  . TYR B 1 74  ? 32.15999 10.07729  38.27477  1.000 16.69771 ? 74  TYR B CA  1 
ATOM   1628 C C   . TYR B 1 74  ? 32.74885 8.67272   38.24933  1.000 15.38808 ? 74  TYR B C   1 
ATOM   1629 O O   . TYR B 1 74  ? 33.46346 8.31917   39.19066  1.000 15.19861 ? 74  TYR B O   1 
ATOM   1630 C CB  . TYR B 1 74  ? 31.21103 10.20476  39.47694  1.000 21.97153 ? 74  TYR B CB  1 
ATOM   1631 N N   . VAL B 1 75  ? 32.48216 7.87368   37.21754  1.000 15.89076 ? 75  VAL B N   1 
ATOM   1632 C CA  . VAL B 1 75  ? 33.00297 6.51281   37.17129  1.000 14.53563 ? 75  VAL B CA  1 
ATOM   1633 C C   . VAL B 1 75  ? 32.96368 6.01390   35.73720  1.000 13.84308 ? 75  VAL B C   1 
ATOM   1634 O O   . VAL B 1 75  ? 32.12628 6.43610   34.94147  1.000 15.27268 ? 75  VAL B O   1 
ATOM   1635 C CB  . VAL B 1 75  ? 32.19639 5.58861   38.12301  1.000 14.91602 ? 75  VAL B CB  1 
ATOM   1636 C CG1 . VAL B 1 75  ? 30.81026 5.25839   37.54750  1.000 18.29290 ? 75  VAL B CG1 1 
ATOM   1637 C CG2 . VAL B 1 75  ? 32.98159 4.29760   38.42733  1.000 15.04798 ? 75  VAL B CG2 1 
ATOM   1638 N N   . CYS B 1 76  ? 33.86715 5.08556   35.41041  1.000 15.12875 ? 76  CYS B N   1 
ATOM   1639 C CA  . CYS B 1 76  ? 33.70799 4.29567   34.19359  1.000 15.34967 ? 76  CYS B CA  1 
ATOM   1640 C C   . CYS B 1 76  ? 34.05211 2.84659   34.50228  1.000 14.05148 ? 76  CYS B C   1 
ATOM   1641 O O   . CYS B 1 76  ? 34.80249 2.55557   35.43630  1.000 15.50872 ? 76  CYS B O   1 
ATOM   1642 C CB  . CYS B 1 76  ? 34.51094 4.81714   32.98860  1.000 14.96260 ? 76  CYS B CB  1 
ATOM   1643 S SG  . CYS B 1 76  ? 36.28738 4.91123   33.23938  1.000 15.55071 ? 76  CYS B SG  1 
ATOM   1644 N N   . VAL B 1 77  ? 33.44532 1.93933   33.74002  1.000 13.69544 ? 77  VAL B N   1 
ATOM   1645 C CA  . VAL B 1 77  ? 33.45241 0.51744   34.06570  1.000 13.45522 ? 77  VAL B CA  1 
ATOM   1646 C C   . VAL B 1 77  ? 33.52619 -0.27432  32.76752  1.000 15.16340 ? 77  VAL B C   1 
ATOM   1647 O O   . VAL B 1 77  ? 32.76512 -0.00879  31.82867  1.000 16.98272 ? 77  VAL B O   1 
ATOM   1648 C CB  . VAL B 1 77  ? 32.18891 0.12980   34.86472  1.000 13.95989 ? 77  VAL B CB  1 
ATOM   1649 C CG1 . VAL B 1 77  ? 32.27131 -1.30284  35.25931  1.000 15.96131 ? 77  VAL B CG1 1 
ATOM   1650 C CG2 . VAL B 1 77  ? 32.03577 0.98541   36.12605  1.000 17.41806 ? 77  VAL B CG2 1 
ATOM   1651 N N   . PHE B 1 78  ? 34.41041 -1.27146  32.72351  1.000 14.60903 ? 78  PHE B N   1 
ATOM   1652 C CA  . PHE B 1 78  ? 34.65064 -2.06695  31.52119  1.000 13.57714 ? 78  PHE B CA  1 
ATOM   1653 C C   . PHE B 1 78  ? 34.37053 -3.53301  31.83837  1.000 14.70525 ? 78  PHE B C   1 
ATOM   1654 O O   . PHE B 1 78  ? 35.08733 -4.14345  32.63667  1.000 15.11090 ? 78  PHE B O   1 
ATOM   1655 C CB  . PHE B 1 78  ? 36.07661 -1.80459  31.02029  1.000 13.56547 ? 78  PHE B CB  1 
ATOM   1656 C CG  . PHE B 1 78  ? 36.28983 -0.35849  30.69468  1.000 14.14104 ? 78  PHE B CG  1 
ATOM   1657 C CD1 . PHE B 1 78  ? 35.82954 0.14794   29.49472  1.000 15.92481 ? 78  PHE B CD1 1 
ATOM   1658 C CD2 . PHE B 1 78  ? 36.82104 0.51613   31.63085  1.000 15.24823 ? 78  PHE B CD2 1 
ATOM   1659 C CE1 . PHE B 1 78  ? 35.93639 1.49730   29.19527  1.000 16.61712 ? 78  PHE B CE1 1 
ATOM   1660 C CE2 . PHE B 1 78  ? 36.92704 1.87842   31.33472  1.000 14.32604 ? 78  PHE B CE2 1 
ATOM   1661 C CZ  . PHE B 1 78  ? 36.48947 2.35256   30.11600  1.000 16.01707 ? 78  PHE B CZ  1 
ATOM   1662 N N   . PHE B 1 79  ? 33.31403 -4.07998  31.22176  1.000 15.53787 ? 79  PHE B N   1 
ATOM   1663 C CA  . PHE B 1 79  ? 32.73118 -5.36969  31.58345  1.000 13.31560 ? 79  PHE B CA  1 
ATOM   1664 C C   . PHE B 1 79  ? 33.21970 -6.48538  30.67501  1.000 15.72984 ? 79  PHE B C   1 
ATOM   1665 O O   . PHE B 1 79  ? 33.21366 -6.34652  29.44731  1.000 15.77419 ? 79  PHE B O   1 
ATOM   1666 C CB  . PHE B 1 79  ? 31.20819 -5.31476  31.43063  1.000 16.76716 ? 79  PHE B CB  1 
ATOM   1667 C CG  . PHE B 1 79  ? 30.53822 -4.31284  32.31722  1.000 16.69974 ? 79  PHE B CG  1 
ATOM   1668 C CD1 . PHE B 1 79  ? 30.39634 -2.99323  31.91274  1.000 16.65639 ? 79  PHE B CD1 1 
ATOM   1669 C CD2 . PHE B 1 79  ? 30.02259 -4.69569  33.54313  1.000 16.68734 ? 79  PHE B CD2 1 
ATOM   1670 C CE1 . PHE B 1 79  ? 29.76398 -2.06174  32.73215  1.000 14.88393 ? 79  PHE B CE1 1 
ATOM   1671 C CE2 . PHE B 1 79  ? 29.40518 -3.78358  34.36183  1.000 16.08100 ? 79  PHE B CE2 1 
ATOM   1672 C CZ  . PHE B 1 79  ? 29.26178 -2.47136  33.95633  1.000 17.23368 ? 79  PHE B CZ  1 
ATOM   1673 N N   . CYS B 1 80  ? 33.54345 -7.62597  31.28996  1.000 14.89940 ? 80  CYS B N   1 
ATOM   1674 C CA  . CYS B 1 80  ? 33.94912 -8.83733  30.58736  1.000 16.27678 ? 80  CYS B CA  1 
ATOM   1675 C C   . CYS B 1 80  ? 33.05313 -9.97913  31.03488  1.000 17.34842 ? 80  CYS B C   1 
ATOM   1676 O O   . CYS B 1 80  ? 33.01333 -10.31007 32.22394  1.000 16.91671 ? 80  CYS B O   1 
ATOM   1677 C CB  . CYS B 1 80  ? 35.40223 -9.19094  30.90960  1.000 15.17680 ? 80  CYS B CB  1 
ATOM   1678 S SG  . CYS B 1 80  ? 36.62104 -7.94810  30.36901  0.933 16.13889 ? 80  CYS B SG  1 
ATOM   1679 N N   . ASN B 1 81  ? 32.36247 -10.59247 30.08114  1.000 17.52945 ? 81  ASN B N   1 
ATOM   1680 C CA  . ASN B 1 81  ? 31.58677 -11.79149 30.36406  1.000 17.36589 ? 81  ASN B CA  1 
ATOM   1681 C C   . ASN B 1 81  ? 32.48888 -13.01485 30.36570  1.000 17.73016 ? 81  ASN B C   1 
ATOM   1682 O O   . ASN B 1 81  ? 33.28497 -13.21123 29.43997  1.000 18.67334 ? 81  ASN B O   1 
ATOM   1683 C CB  . ASN B 1 81  ? 30.48796 -11.95292 29.31898  1.000 17.31808 ? 81  ASN B CB  1 
ATOM   1684 C CG  . ASN B 1 81  ? 29.36661 -10.94924 29.50960  1.000 17.88776 ? 81  ASN B CG  1 
ATOM   1685 O OD1 . ASN B 1 81  ? 29.01627 -10.61822 30.64407  1.000 20.66921 ? 81  ASN B OD1 1 
ATOM   1686 N ND2 . ASN B 1 81  ? 28.80424 -10.45065 28.40748  1.000 20.45102 ? 81  ASN B ND2 1 
ATOM   1687 N N   . HIS B 1 82  ? 32.38025 -13.82305 31.41957  1.000 16.20827 ? 82  HIS B N   1 
ATOM   1688 C CA  . HIS B 1 82  ? 33.16520 -15.05082 31.52352  1.000 17.61757 ? 82  HIS B CA  1 
ATOM   1689 C C   . HIS B 1 82  ? 32.45888 -15.98155 32.49526  1.000 19.20639 ? 82  HIS B C   1 
ATOM   1690 O O   . HIS B 1 82  ? 31.71084 -15.53384 33.36556  1.000 19.14634 ? 82  HIS B O   1 
ATOM   1691 C CB  . HIS B 1 82  ? 34.60836 -14.78052 31.98108  1.000 19.14574 ? 82  HIS B CB  1 
ATOM   1692 C CG  . HIS B 1 82  ? 34.71470 -14.28556 33.39167  1.000 17.64719 ? 82  HIS B CG  1 
ATOM   1693 N ND1 . HIS B 1 82  ? 35.10718 -15.08487 34.44281  1.000 15.83964 ? 82  HIS B ND1 1 
ATOM   1694 C CD2 . HIS B 1 82  ? 34.46534 -13.06367 33.92592  1.000 15.80618 ? 82  HIS B CD2 1 
ATOM   1695 C CE1 . HIS B 1 82  ? 35.10057 -14.38118 35.56114  1.000 14.68594 ? 82  HIS B CE1 1 
ATOM   1696 N NE2 . HIS B 1 82  ? 34.70615 -13.15312 35.27552  1.000 16.81354 ? 82  HIS B NE2 1 
ATOM   1697 N N   . SER B 1 83  ? 32.70614 -17.27968 32.34091  1.000 19.53349 ? 83  SER B N   1 
ATOM   1698 C CA  . SER B 1 83  ? 32.06539 -18.29315 33.19258  1.000 20.64941 ? 83  SER B CA  1 
ATOM   1699 C C   . SER B 1 83  ? 30.55729 -18.03491 33.18817  1.000 18.42228 ? 83  SER B C   1 
ATOM   1700 O O   . SER B 1 83  ? 29.98053 -17.82496 32.11320  1.000 20.57921 ? 83  SER B O   1 
ATOM   1701 C CB  . SER B 1 83  ? 32.73603 -18.30381 34.55677  1.000 21.38646 ? 83  SER B CB  1 
ATOM   1702 O OG  . SER B 1 83  ? 32.08867 -19.20335 35.44449  1.000 25.19706 ? 83  SER B OG  1 
ATOM   1703 N N   . THR B 1 84  ? 29.90416 -17.98266 34.34089  1.000 19.88503 ? 84  THR B N   1 
ATOM   1704 C CA  . THR B 1 84  ? 28.45527 -17.84756 34.42401  1.000 19.84238 ? 84  THR B CA  1 
ATOM   1705 C C   . THR B 1 84  ? 28.00382 -16.40161 34.59034  1.000 18.81665 ? 84  THR B C   1 
ATOM   1706 O O   . THR B 1 84  ? 26.79387 -16.14440 34.66067  1.000 17.72906 ? 84  THR B O   1 
ATOM   1707 C CB  . THR B 1 84  ? 27.92997 -18.68319 35.60122  1.000 20.20542 ? 84  THR B CB  1 
ATOM   1708 O OG1 . THR B 1 84  ? 28.66527 -18.35711 36.78441  1.000 20.94486 ? 84  THR B OG1 1 
ATOM   1709 C CG2 . THR B 1 84  ? 28.09438 -20.19430 35.32316  1.000 20.56074 ? 84  THR B CG2 1 
ATOM   1710 N N   . GLY B 1 85  ? 28.92973 -15.44934 34.64267  1.000 18.08255 ? 85  GLY B N   1 
ATOM   1711 C CA  . GLY B 1 85  ? 28.59541 -14.06432 34.95525  1.000 15.82918 ? 85  GLY B CA  1 
ATOM   1712 C C   . GLY B 1 85  ? 29.52315 -13.07392 34.29481  1.000 17.04126 ? 85  GLY B C   1 
ATOM   1713 O O   . GLY B 1 85  ? 29.84567 -13.19947 33.10518  1.000 17.24940 ? 85  GLY B O   1 
ATOM   1714 N N   . CYS B 1 86  ? 29.94041 -12.07079 35.05912  1.000 16.06497 ? 86  CYS B N   1 
ATOM   1715 C CA  . CYS B 1 86  ? 30.66506 -10.94514 34.49139  1.000 15.71751 ? 86  CYS B CA  1 
ATOM   1716 C C   . CYS B 1 86  ? 31.63454 -10.43082 35.54074  1.000 14.88625 ? 86  CYS B C   1 
ATOM   1717 O O   . CYS B 1 86  ? 31.33373 -10.44754 36.73630  1.000 17.26136 ? 86  CYS B O   1 
ATOM   1718 C CB  . CYS B 1 86  ? 29.66134 -9.84691  34.08590  1.000 23.12545 ? 86  CYS B CB  1 
ATOM   1719 S SG  . CYS B 1 86  ? 30.33354 -8.26627  33.54198  0.577 20.22102 ? 86  CYS B SG  1 
ATOM   1720 N N   . THR B 1 87  ? 32.80536 -9.96786  35.09002  1.000 14.39467 ? 87  THR B N   1 
ATOM   1721 C CA  . THR B 1 87  ? 33.68512 -9.16645  35.93360  1.000 17.04782 ? 87  THR B CA  1 
ATOM   1722 C C   . THR B 1 87  ? 34.03941 -7.88278  35.19834  1.000 16.04056 ? 87  THR B C   1 
ATOM   1723 O O   . THR B 1 87  ? 34.27245 -7.89355  33.98500  1.000 16.12111 ? 87  THR B O   1 
ATOM   1724 C CB  . THR B 1 87  ? 34.96147 -9.93202  36.32741  1.000 17.29031 ? 87  THR B CB  1 
ATOM   1725 O OG1 . THR B 1 87  ? 34.59894 -11.08073 37.10888  1.000 19.19751 ? 87  THR B OG1 1 
ATOM   1726 C CG2 . THR B 1 87  ? 35.89720 -9.04740  37.14924  1.000 18.20615 ? 87  THR B CG2 1 
ATOM   1727 N N   . ALA B 1 88  ? 34.06008 -6.78143  35.93825  1.000 15.63587 ? 88  ALA B N   1 
ATOM   1728 C CA  . ALA B 1 88  ? 34.31194 -5.46391  35.38412  1.000 14.76943 ? 88  ALA B CA  1 
ATOM   1729 C C   . ALA B 1 88  ? 35.50835 -4.80721  36.06034  1.000 15.84685 ? 88  ALA B C   1 
ATOM   1730 O O   . ALA B 1 88  ? 35.75668 -4.98815  37.25912  1.000 15.74904 ? 88  ALA B O   1 
ATOM   1731 C CB  . ALA B 1 88  ? 33.08632 -4.57839  35.55837  1.000 17.69119 ? 88  ALA B CB  1 
ATOM   1732 N N   . TYR B 1 89  ? 36.24315 -4.03022  35.26837  1.000 13.33875 ? 89  TYR B N   1 
ATOM   1733 C CA  . TYR B 1 89  ? 37.37045 -3.23288  35.73884  1.000 13.44863 ? 89  TYR B CA  1 
ATOM   1734 C C   . TYR B 1 89  ? 36.89958 -1.79253  35.86398  1.000 14.44839 ? 89  TYR B C   1 
ATOM   1735 O O   . TYR B 1 89  ? 36.31289 -1.24747  34.91991  1.000 15.11478 ? 89  TYR B O   1 
ATOM   1736 C CB  . TYR B 1 89  ? 38.52768 -3.32722  34.73741  1.000 13.60280 ? 89  TYR B CB  1 
ATOM   1737 C CG  . TYR B 1 89  ? 38.97523 -4.74843  34.48820  1.000 14.61941 ? 89  TYR B CG  1 
ATOM   1738 C CD1 . TYR B 1 89  ? 39.95790 -5.33839  35.27377  1.000 13.62347 ? 89  TYR B CD1 1 
ATOM   1739 C CD2 . TYR B 1 89  ? 38.39670 -5.49844  33.47367  1.000 14.60933 ? 89  TYR B CD2 1 
ATOM   1740 C CE1 . TYR B 1 89  ? 40.35218 -6.66457  35.05432  1.000 14.89383 ? 89  TYR B CE1 1 
ATOM   1741 C CE2 . TYR B 1 89  ? 38.78289 -6.81283  33.23808  1.000 15.13275 ? 89  TYR B CE2 1 
ATOM   1742 C CZ  . TYR B 1 89  ? 39.75476 -7.38627  34.03069  1.000 14.39696 ? 89  TYR B CZ  1 
ATOM   1743 O OH  . TYR B 1 89  ? 40.12618 -8.70014  33.78567  1.000 14.93090 ? 89  TYR B OH  1 
ATOM   1744 N N   . VAL B 1 90  ? 37.14274 -1.18890  37.02649  1.000 12.40391 ? 90  VAL B N   1 
ATOM   1745 C CA  . VAL B 1 90  ? 36.55216 0.09665   37.40792  1.000 12.98410 ? 90  VAL B CA  1 
ATOM   1746 C C   . VAL B 1 90  ? 37.61871 1.17922   37.46962  1.000 15.82468 ? 90  VAL B C   1 
ATOM   1747 O O   . VAL B 1 90  ? 38.71082 0.95870   38.00584  1.000 16.36614 ? 90  VAL B O   1 
ATOM   1748 C CB  . VAL B 1 90  ? 35.87549 -0.02275  38.78493  1.000 15.36043 ? 90  VAL B CB  1 
ATOM   1749 C CG1 . VAL B 1 90  ? 35.31793 1.33224   39.23615  1.000 15.85917 ? 90  VAL B CG1 1 
ATOM   1750 C CG2 . VAL B 1 90  ? 34.77675 -1.08353  38.74565  1.000 15.68208 ? 90  VAL B CG2 1 
ATOM   1751 N N   . TYR B 1 91  ? 37.27815 2.37251   36.96902  1.000 13.36467 ? 91  TYR B N   1 
ATOM   1752 C CA  . TYR B 1 91  ? 38.13266 3.54792   37.10574  1.000 13.60048 ? 91  TYR B CA  1 
ATOM   1753 C C   . TYR B 1 91  ? 37.30107 4.71911   37.60639  1.000 13.52574 ? 91  TYR B C   1 
ATOM   1754 O O   . TYR B 1 91  ? 36.27317 5.04494   37.00970  1.000 14.86545 ? 91  TYR B O   1 
ATOM   1755 C CB  . TYR B 1 91  ? 38.80784 3.91320   35.76726  1.000 14.58634 ? 91  TYR B CB  1 
ATOM   1756 C CG  . TYR B 1 91  ? 39.73066 2.82355   35.31099  1.000 14.51630 ? 91  TYR B CG  1 
ATOM   1757 C CD1 . TYR B 1 91  ? 39.24371 1.71815   34.63084  1.000 15.30302 ? 91  TYR B CD1 1 
ATOM   1758 C CD2 . TYR B 1 91  ? 41.08885 2.88401   35.59727  1.000 13.52998 ? 91  TYR B CD2 1 
ATOM   1759 C CE1 . TYR B 1 91  ? 40.08919 0.69587   34.24043  1.000 16.29755 ? 91  TYR B CE1 1 
ATOM   1760 C CE2 . TYR B 1 91  ? 41.94878 1.87119   35.20447  1.000 14.58066 ? 91  TYR B CE2 1 
ATOM   1761 C CZ  . TYR B 1 91  ? 41.43876 0.78666   34.51624  1.000 15.55722 ? 91  TYR B CZ  1 
ATOM   1762 O OH  . TYR B 1 91  ? 42.27541 -0.24221  34.11695  1.000 16.65185 ? 91  TYR B OH  1 
ATOM   1763 N N   . GLY B 1 92  ? 37.75816 5.36228   38.67976  1.000 14.30798 ? 92  GLY B N   1 
ATOM   1764 C CA  . GLY B 1 92  ? 37.09547 6.56421   39.15072  1.000 13.91159 ? 92  GLY B CA  1 
ATOM   1765 C C   . GLY B 1 92  ? 37.33221 7.74134   38.22347  1.000 16.11738 ? 92  GLY B C   1 
ATOM   1766 O O   . GLY B 1 92  ? 38.33912 7.82144   37.52960  1.000 16.93442 ? 92  GLY B O   1 
ATOM   1767 N N   . ARG B 1 93  ? 36.37192 8.66059   38.19273  1.000 13.57708 ? 93  ARG B N   1 
ATOM   1768 C CA  . ARG B 1 93  ? 36.50365 9.87748   37.40475  1.000 13.09110 ? 93  ARG B CA  1 
ATOM   1769 C C   . ARG B 1 93  ? 36.10076 11.07800  38.25077  1.000 16.17564 ? 93  ARG B C   1 
ATOM   1770 O O   . ARG B 1 93  ? 35.32548 10.95974  39.20018  1.000 15.85567 ? 93  ARG B O   1 
ATOM   1771 C CB  . ARG B 1 93  ? 35.61254 9.82459   36.15070  1.000 14.70758 ? 93  ARG B CB  1 
ATOM   1772 C CG  . ARG B 1 93  ? 35.76306 8.54600   35.31663  1.000 14.81318 ? 93  ARG B CG  1 
ATOM   1773 C CD  . ARG B 1 93  ? 35.01615 8.64070   33.99045  1.000 15.88700 ? 93  ARG B CD  1 
ATOM   1774 N NE  . ARG B 1 93  ? 35.66475 9.53045   33.02060  1.000 15.59060 ? 93  ARG B NE  1 
ATOM   1775 C CZ  . ARG B 1 93  ? 35.02046 10.41645  32.26008  1.000 16.40030 ? 93  ARG B CZ  1 
ATOM   1776 N NH1 . ARG B 1 93  ? 33.70876 10.57577  32.36935  1.000 17.96261 ? 93  ARG B NH1 1 
ATOM   1777 N NH2 . ARG B 1 93  ? 35.68753 11.18520  31.40592  1.000 16.37516 ? 93  ARG B NH2 1 
ATOM   1778 N N   . GLY B 1 94  ? 36.64558 12.24024  37.90450  1.000 15.44059 ? 94  GLY B N   1 
ATOM   1779 C CA  . GLY B 1 94  ? 36.23113 13.47316  38.54641  1.000 15.69043 ? 94  GLY B CA  1 
ATOM   1780 C C   . GLY B 1 94  ? 36.60578 13.62566  40.00266  1.000 14.94836 ? 94  GLY B C   1 
ATOM   1781 O O   . GLY B 1 94  ? 36.11275 14.55132  40.65654  1.000 19.06829 ? 94  GLY B O   1 
ATOM   1782 N N   . GLY B 1 95  ? 37.46960 12.76755  40.53469  1.000 13.99463 ? 95  GLY B N   1 
ATOM   1783 C CA  . GLY B 1 95  ? 37.80206 12.77685  41.94149  1.000 16.27348 ? 95  GLY B CA  1 
ATOM   1784 C C   . GLY B 1 95  ? 37.12112 11.68605  42.74629  1.000 16.65100 ? 95  GLY B C   1 
ATOM   1785 O O   . GLY B 1 95  ? 37.51458 11.44499  43.89631  1.000 18.65183 ? 95  GLY B O   1 
ATOM   1786 N N   . TYR B 1 96  ? 36.15378 10.99528  42.16873  1.000 13.83175 ? 96  TYR B N   1 
ATOM   1787 C CA  . TYR B 1 96  ? 35.42825 9.96531   42.90003  1.000 13.56695 ? 96  TYR B CA  1 
ATOM   1788 C C   . TYR B 1 96  ? 36.07842 8.59537   42.73604  1.000 17.45375 ? 96  TYR B C   1 
ATOM   1789 O O   . TYR B 1 96  ? 36.91872 8.37065   41.85749  1.000 15.99318 ? 96  TYR B O   1 
ATOM   1790 C CB  . TYR B 1 96  ? 33.96828 9.91723   42.43693  1.000 15.19761 ? 96  TYR B CB  1 
ATOM   1791 C CG  . TYR B 1 96  ? 33.11931 11.00083  43.05751  1.000 16.31573 ? 96  TYR B CG  1 
ATOM   1792 C CD1 . TYR B 1 96  ? 33.34418 12.33378  42.75893  1.000 18.78417 ? 96  TYR B CD1 1 
ATOM   1793 C CD2 . TYR B 1 96  ? 32.12730 10.69027  43.97283  1.000 16.89310 ? 96  TYR B CD2 1 
ATOM   1794 C CE1 . TYR B 1 96  ? 32.58202 13.33322  43.33111  1.000 20.67463 ? 96  TYR B CE1 1 
ATOM   1795 C CE2 . TYR B 1 96  ? 31.36954 11.69071  44.56050  1.000 19.02744 ? 96  TYR B CE2 1 
ATOM   1796 C CZ  . TYR B 1 96  ? 31.60248 13.00247  44.22531  1.000 19.54620 ? 96  TYR B CZ  1 
ATOM   1797 O OH  . TYR B 1 96  ? 30.85567 14.01343  44.79520  1.000 21.12347 ? 96  TYR B OH  1 
ATOM   1798 N N   . TYR B 1 97  ? 35.68399 7.68071   43.62238  1.000 15.18603 ? 97  TYR B N   1 
ATOM   1799 C CA  . TYR B 1 97  ? 35.98722 6.26060   43.51932  1.000 14.50385 ? 97  TYR B CA  1 
ATOM   1800 C C   . TYR B 1 97  ? 34.69356 5.49573   43.73982  1.000 14.70353 ? 97  TYR B C   1 
ATOM   1801 O O   . TYR B 1 97  ? 33.68434 6.06747   44.15194  1.000 14.66872 ? 97  TYR B O   1 
ATOM   1802 C CB  . TYR B 1 97  ? 37.05330 5.82430   44.53562  1.000 15.64780 ? 97  TYR B CB  1 
ATOM   1803 C CG  . TYR B 1 97  ? 36.66335 5.96016   46.00128  1.000 16.55863 ? 97  TYR B CG  1 
ATOM   1804 C CD1 . TYR B 1 97  ? 36.03957 4.92184   46.67502  1.000 16.87951 ? 97  TYR B CD1 1 
ATOM   1805 C CD2 . TYR B 1 97  ? 36.96948 7.11276   46.72089  1.000 16.66910 ? 97  TYR B CD2 1 
ATOM   1806 C CE1 . TYR B 1 97  ? 35.70436 5.03098   48.01715  1.000 18.14228 ? 97  TYR B CE1 1 
ATOM   1807 C CE2 . TYR B 1 97  ? 36.64083 7.23196   48.06859  1.000 17.08353 ? 97  TYR B CE2 1 
ATOM   1808 C CZ  . TYR B 1 97  ? 36.00589 6.18486   48.70759  1.000 18.74395 ? 97  TYR B CZ  1 
ATOM   1809 O OH  . TYR B 1 97  ? 35.67622 6.28933   50.04720  1.000 19.57181 ? 97  TYR B OH  1 
ATOM   1810 N N   . LEU B 1 98  ? 34.72004 4.19933   43.46336  1.000 13.17580 ? 98  LEU B N   1 
ATOM   1811 C CA  . LEU B 1 98  ? 33.52758 3.36704   43.56353  1.000 14.30738 ? 98  LEU B CA  1 
ATOM   1812 C C   . LEU B 1 98  ? 33.46366 2.66187   44.91621  1.000 14.91308 ? 98  LEU B C   1 
ATOM   1813 O O   . LEU B 1 98  ? 34.44196 2.03915   45.35980  1.000 15.68108 ? 98  LEU B O   1 
ATOM   1814 C CB  . LEU B 1 98  ? 33.47916 2.35057   42.42256  1.000 15.64056 ? 98  LEU B CB  1 
ATOM   1815 C CG  . LEU B 1 98  ? 32.24991 1.43635   42.44053  1.000 16.22577 ? 98  LEU B CG  1 
ATOM   1816 C CD1 . LEU B 1 98  ? 30.97334 2.22624   42.22933  1.000 14.97534 ? 98  LEU B CD1 1 
ATOM   1817 C CD2 . LEU B 1 98  ? 32.36127 0.34373   41.39232  1.000 15.60280 ? 98  LEU B CD2 1 
ATOM   1818 N N   . SER B 1 99  ? 32.30206 2.75161   45.56200  1.000 14.76570 ? 99  SER B N   1 
ATOM   1819 C CA  . SER B 1 99  ? 32.10111 2.06483   46.82391  1.000 14.81557 ? 99  SER B CA  1 
ATOM   1820 C C   . SER B 1 99  ? 32.12454 0.55458   46.62186  1.000 15.55488 ? 99  SER B C   1 
ATOM   1821 O O   . SER B 1 99  ? 31.62383 0.02342   45.63138  1.000 18.70718 ? 99  SER B O   1 
ATOM   1822 C CB  . SER B 1 99  ? 30.75436 2.46265   47.42688  1.000 17.32400 ? 99  SER B CB  1 
ATOM   1823 O OG  . SER B 1 99  ? 30.50707 1.70280   48.60215  1.000 18.98231 ? 99  SER B OG  1 
ATOM   1824 N N   . MET B 1 100 ? 32.69157 -0.12845  47.59424  1.000 18.67711 ? 100 MET B N   1 
ATOM   1825 C CA  . MET B 1 100 ? 32.69791 -1.57801  47.69526  1.000 18.91688 ? 100 MET B CA  1 
ATOM   1826 C C   . MET B 1 100 ? 31.67431 -2.14359  48.67488  1.000 21.48916 ? 100 MET B C   1 
ATOM   1827 O O   . MET B 1 100 ? 31.67061 -3.35849  48.90623  1.000 23.77547 ? 100 MET B O   1 
ATOM   1828 C CB  . MET B 1 100 ? 34.12624 -2.06416  47.95600  1.000 22.31691 ? 100 MET B CB  1 
ATOM   1829 C CG  . MET B 1 100 ? 34.65466 -1.40385  49.22700  1.000 26.70779 ? 100 MET B CG  1 
ATOM   1830 S SD  . MET B 1 100 ? 34.22162 -1.87123  50.86731  0.779 26.64291 ? 100 MET B SD  1 
ATOM   1831 C CE  . MET B 1 100 ? 35.04124 -3.46900  51.04642  1.000 29.85893 ? 100 MET B CE  1 
ATOM   1832 N N   . TYR B 1 101 ? 30.79264 -1.31162  49.22889  1.000 20.32444 ? 101 TYR B N   1 
ATOM   1833 C CA  . TYR B 1 101 ? 29.78854 -1.82601  50.15738  1.000 21.36864 ? 101 TYR B CA  1 
ATOM   1834 C C   . TYR B 1 101 ? 28.81589 -2.76989  49.45050  1.000 21.09729 ? 101 TYR B C   1 
ATOM   1835 O O   . TYR B 1 101 ? 28.59266 -2.69363  48.23937  1.000 19.79606 ? 101 TYR B O   1 
ATOM   1836 C CB  . TYR B 1 101 ? 28.98991 -0.69962  50.81892  1.000 23.86323 ? 101 TYR B CB  1 
ATOM   1837 C CG  . TYR B 1 101 ? 29.72220 0.05289   51.90371  1.000 28.37563 ? 101 TYR B CG  1 
ATOM   1838 C CD1 . TYR B 1 101 ? 30.50413 -0.61338  52.83492  1.000 33.07966 ? 101 TYR B CD1 1 
ATOM   1839 C CD2 . TYR B 1 101 ? 29.57406 1.43034   52.03515  1.000 30.52218 ? 101 TYR B CD2 1 
ATOM   1840 C CE1 . TYR B 1 101 ? 31.16963 0.07643   53.83755  1.000 35.48054 ? 101 TYR B CE1 1 
ATOM   1841 C CE2 . TYR B 1 101 ? 30.22544 2.12679   53.03424  1.000 34.32820 ? 101 TYR B CE2 1 
ATOM   1842 C CZ  . TYR B 1 101 ? 31.02231 1.44638   53.93344  1.000 36.48499 ? 101 TYR B CZ  1 
ATOM   1843 O OH  . TYR B 1 101 ? 31.67337 2.14544   54.92807  1.000 38.35588 ? 101 TYR B OH  1 
ATOM   1844 N N   . LYS B 1 102 ? 28.17960 -3.62869  50.25757  1.000 23.77685 ? 102 LYS B N   1 
ATOM   1845 C CA  . LYS B 1 102 ? 27.39967 -4.74464  49.72341  1.000 21.22094 ? 102 LYS B CA  1 
ATOM   1846 C C   . LYS B 1 102 ? 26.33425 -4.29493  48.73285  1.000 18.69320 ? 102 LYS B C   1 
ATOM   1847 O O   . LYS B 1 102 ? 26.14168 -4.93407  47.69596  1.000 21.76459 ? 102 LYS B O   1 
ATOM   1848 C CB  . LYS B 1 102 ? 26.76443 -5.54385  50.86453  1.000 27.35992 ? 102 LYS B CB  1 
ATOM   1849 N N   . GLY B 1 103 ? 25.61958 -3.21624  49.02754  1.000 21.95806 ? 103 GLY B N   1 
ATOM   1850 C CA  . GLY B 1 103 ? 24.53888 -2.79962  48.16040  1.000 20.88714 ? 103 GLY B CA  1 
ATOM   1851 C C   . GLY B 1 103 ? 24.88757 -1.79043  47.08488  1.000 20.32765 ? 103 GLY B C   1 
ATOM   1852 O O   . GLY B 1 103 ? 23.98241 -1.31453  46.38963  1.000 20.15946 ? 103 GLY B O   1 
ATOM   1853 N N   . ASP B 1 104 ? 26.16681 -1.46715  46.89198  1.000 19.30941 ? 104 ASP B N   1 
ATOM   1854 C CA  . ASP B 1 104 ? 26.52480 -0.24840  46.17417  1.000 19.15541 ? 104 ASP B CA  1 
ATOM   1855 C C   . ASP B 1 104 ? 26.94863 -0.45378  44.71723  1.000 19.38336 ? 104 ASP B C   1 
ATOM   1856 O O   . ASP B 1 104 ? 27.35548 0.52116   44.07424  1.000 19.41944 ? 104 ASP B O   1 
ATOM   1857 C CB  . ASP B 1 104 ? 27.60509 0.52092   46.93582  1.000 21.44168 ? 104 ASP B CB  1 
ATOM   1858 C CG  . ASP B 1 104 ? 27.07242 1.20202   48.17782  1.000 19.84775 ? 104 ASP B CG  1 
ATOM   1859 O OD1 . ASP B 1 104 ? 25.83748 1.19063   48.38967  1.000 21.97154 ? 104 ASP B OD1 1 
ATOM   1860 O OD2 . ASP B 1 104 ? 27.88649 1.72139   48.96244  1.000 19.51521 ? 104 ASP B OD2 1 
ATOM   1861 N N   . VAL B 1 105 ? 26.88385 -1.67002  44.16667  1.000 17.06104 ? 105 VAL B N   1 
ATOM   1862 C CA  . VAL B 1 105 ? 27.24537 -1.78515  42.75647  1.000 16.29484 ? 105 VAL B CA  1 
ATOM   1863 C C   . VAL B 1 105 ? 26.33948 -2.86161  42.15656  1.000 19.35707 ? 105 VAL B C   1 
ATOM   1864 O O   . VAL B 1 105 ? 26.60308 -4.06222  42.30946  1.000 18.54119 ? 105 VAL B O   1 
ATOM   1865 C CB  . VAL B 1 105 ? 28.73151 -2.18560  42.58539  1.000 17.77022 ? 105 VAL B CB  1 
ATOM   1866 C CG1 . VAL B 1 105 ? 29.08034 -2.33602  41.12842  1.000 20.87706 ? 105 VAL B CG1 1 
ATOM   1867 C CG2 . VAL B 1 105 ? 29.74619 -1.36254  43.39336  1.000 21.14685 ? 105 VAL B CG2 1 
ATOM   1868 N N   . LYS B 1 106 ? 25.25842 -2.46187  41.49224  1.000 17.09970 ? 106 LYS B N   1 
ATOM   1869 C CA  . LYS B 1 106 ? 24.26703 -3.40862  40.98605  1.000 17.81577 ? 106 LYS B CA  1 
ATOM   1870 C C   . LYS B 1 106 ? 24.29946 -3.47900  39.46391  1.000 17.91483 ? 106 LYS B C   1 
ATOM   1871 O O   . LYS B 1 106 ? 24.35763 -2.45065  38.78540  1.000 18.25528 ? 106 LYS B O   1 
ATOM   1872 C CB  . LYS B 1 106 ? 22.84221 -3.01979  41.41052  1.000 17.52023 ? 106 LYS B CB  1 
ATOM   1873 C CG  . LYS B 1 106 ? 22.52079 -3.10137  42.89301  1.000 20.76500 ? 106 LYS B CG  1 
ATOM   1874 C CD  . LYS B 1 106 ? 21.18850 -2.38766  43.17285  1.000 21.49862 ? 106 LYS B CD  1 
ATOM   1875 C CE  . LYS B 1 106 ? 21.01478 -2.05798  44.64963  1.000 23.11942 ? 106 LYS B CE  1 
ATOM   1876 N NZ  . LYS B 1 106 ? 20.78235 -3.26754  45.48668  1.000 24.47106 ? 106 LYS B NZ  1 
ATOM   1877 N N   . LEU B 1 107 ? 24.23229 -4.69385  38.92154  1.000 17.90775 ? 107 LEU B N   1 
ATOM   1878 C CA  . LEU B 1 107 ? 24.14733 -4.90555  37.47825  1.000 16.02257 ? 107 LEU B CA  1 
ATOM   1879 C C   . LEU B 1 107 ? 22.82817 -5.60216  37.19011  1.000 19.62670 ? 107 LEU B C   1 
ATOM   1880 O O   . LEU B 1 107 ? 22.55873 -6.66503  37.75562  1.000 18.20149 ? 107 LEU B O   1 
ATOM   1881 C CB  . LEU B 1 107 ? 25.29627 -5.79343  36.99500  1.000 17.70543 ? 107 LEU B CB  1 
ATOM   1882 C CG  . LEU B 1 107 ? 25.33384 -6.11656  35.49831  1.000 16.76107 ? 107 LEU B CG  1 
ATOM   1883 C CD1 . LEU B 1 107 ? 25.55356 -4.86152  34.64454  1.000 17.36508 ? 107 LEU B CD1 1 
ATOM   1884 C CD2 . LEU B 1 107 ? 26.44621 -7.12479  35.23045  1.000 17.96437 ? 107 LEU B CD2 1 
ATOM   1885 N N   . ASN B 1 108 ? 22.00483 -5.00836  36.32137  1.000 18.91869 ? 108 ASN B N   1 
ATOM   1886 C CA  . ASN B 1 108 ? 20.67229 -5.55929  36.05737  1.000 19.96564 ? 108 ASN B CA  1 
ATOM   1887 C C   . ASN B 1 108 ? 19.89842 -5.73097  37.36136  1.000 20.47509 ? 108 ASN B C   1 
ATOM   1888 O O   . ASN B 1 108 ? 19.12153 -6.67796  37.52982  1.000 22.03836 ? 108 ASN B O   1 
ATOM   1889 C CB  . ASN B 1 108 ? 20.76447 -6.86238  35.25071  1.000 20.20515 ? 108 ASN B CB  1 
ATOM   1890 C CG  . ASN B 1 108 ? 19.51449 -7.14240  34.43804  1.000 23.10565 ? 108 ASN B CG  1 
ATOM   1891 O OD1 . ASN B 1 108 ? 18.57833 -6.35189  34.42600  1.000 21.16331 ? 108 ASN B OD1 1 
ATOM   1892 N ND2 . ASN B 1 108 ? 19.51141 -8.26399  33.72734  1.000 30.37978 ? 108 ASN B ND2 1 
ATOM   1893 N N   . SER B 1 109 ? 20.14734 -4.81691  38.30373  1.000 19.39991 ? 109 SER B N   1 
ATOM   1894 C CA  . SER B 1 109 ? 19.55649 -4.76234  39.63824  1.000 20.62632 ? 109 SER B CA  1 
ATOM   1895 C C   . SER B 1 109 ? 20.04212 -5.85735  40.58246  1.000 18.37508 ? 109 SER B C   1 
ATOM   1896 O O   . SER B 1 109 ? 19.52207 -5.96605  41.70022  1.000 20.84705 ? 109 SER B O   1 
ATOM   1897 C CB  . SER B 1 109 ? 18.02534 -4.65372  39.62015  1.000 22.60120 ? 109 SER B CB  1 
ATOM   1898 O OG  . SER B 1 109 ? 17.64002 -3.37606  39.13667  1.000 27.13808 ? 109 SER B OG  1 
ATOM   1899 N N   . VAL B 1 110 ? 21.06221 -6.63117  40.19717  1.000 16.50244 ? 110 VAL B N   1 
ATOM   1900 C CA  . VAL B 1 110 ? 21.59771 -7.71707  41.01773  1.000 18.13536 ? 110 VAL B CA  1 
ATOM   1901 C C   . VAL B 1 110 ? 22.83504 -7.22650  41.76697  1.000 16.05478 ? 110 VAL B C   1 
ATOM   1902 O O   . VAL B 1 110 ? 23.71842 -6.58405  41.17598  1.000 16.41091 ? 110 VAL B O   1 
ATOM   1903 C CB  . VAL B 1 110 ? 21.91518 -8.94521  40.14879  1.000 17.26737 ? 110 VAL B CB  1 
ATOM   1904 C CG1 . VAL B 1 110 ? 22.54491 -10.04952 40.98888  1.000 18.26749 ? 110 VAL B CG1 1 
ATOM   1905 C CG2 . VAL B 1 110 ? 20.62070 -9.46071  39.49174  1.000 18.63544 ? 110 VAL B CG2 1 
ATOM   1906 N N   . ASP B 1 111 ? 22.90090 -7.51259  43.06846  1.000 16.91600 ? 111 ASP B N   1 
ATOM   1907 C CA  . ASP B 1 111 ? 24.03499 -7.05787  43.86575  1.000 17.09055 ? 111 ASP B CA  1 
ATOM   1908 C C   . ASP B 1 111 ? 25.29677 -7.83666  43.51823  1.000 17.25603 ? 111 ASP B C   1 
ATOM   1909 O O   . ASP B 1 111 ? 25.25641 -9.02321  43.19589  1.000 16.84107 ? 111 ASP B O   1 
ATOM   1910 C CB  . ASP B 1 111 ? 23.75824 -7.21107  45.36121  1.000 17.20511 ? 111 ASP B CB  1 
ATOM   1911 C CG  . ASP B 1 111 ? 22.75407 -6.20404  45.87417  1.000 20.62171 ? 111 ASP B CG  1 
ATOM   1912 O OD1 . ASP B 1 111 ? 22.78984 -5.03289  45.43581  1.000 21.08424 ? 111 ASP B OD1 1 
ATOM   1913 O OD2 . ASP B 1 111 ? 21.94029 -6.58750  46.73592  1.000 25.30171 ? 111 ASP B OD2 1 
ATOM   1914 N N   . HIS B 1 112 ? 26.43297 -7.15137  43.60017  1.000 15.96350 ? 112 HIS B N   1 
ATOM   1915 C CA  . HIS B 1 112 ? 27.70312 -7.74987  43.22489  1.000 17.50796 ? 112 HIS B CA  1 
ATOM   1916 C C   . HIS B 1 112 ? 28.09875 -8.85398  44.19302  1.000 17.51253 ? 112 HIS B C   1 
ATOM   1917 O O   . HIS B 1 112 ? 27.61238 -8.94072  45.32461  1.000 18.82130 ? 112 HIS B O   1 
ATOM   1918 C CB  . HIS B 1 112 ? 28.81493 -6.69779  43.23256  1.000 16.82999 ? 112 HIS B CB  1 
ATOM   1919 C CG  . HIS B 1 112 ? 29.05940 -6.08387  44.57638  1.000 18.09470 ? 112 HIS B CG  1 
ATOM   1920 N ND1 . HIS B 1 112 ? 29.80729 -6.70167  45.56041  1.000 18.99502 ? 112 HIS B ND1 1 
ATOM   1921 C CD2 . HIS B 1 112 ? 28.66510 -4.89585  45.09288  1.000 18.84622 ? 112 HIS B CD2 1 
ATOM   1922 C CE1 . HIS B 1 112 ? 29.85044 -5.92323  46.62727  1.000 19.06925 ? 112 HIS B CE1 1 
ATOM   1923 N NE2 . HIS B 1 112 ? 29.16988 -4.81957  46.36623  1.000 18.09337 ? 112 HIS B NE2 1 
ATOM   1924 N N   . ASN B 1 113 ? 29.02345 -9.69474  43.72959  1.000 17.29144 ? 113 ASN B N   1 
ATOM   1925 C CA  . ASN B 1 113 ? 29.70768 -10.64874 44.59030  1.000 19.07714 ? 113 ASN B CA  1 
ATOM   1926 C C   . ASN B 1 113 ? 31.10342 -10.12388 44.92207  1.000 19.42956 ? 113 ASN B C   1 
ATOM   1927 O O   . ASN B 1 113 ? 31.23282 -9.01268  45.45521  1.000 20.29776 ? 113 ASN B O   1 
ATOM   1928 C CB  . ASN B 1 113 ? 29.69914 -12.04067 43.95286  1.000 17.38435 ? 113 ASN B CB  1 
ATOM   1929 C CG  . ASN B 1 113 ? 28.27581 -12.57387 43.76403  1.000 19.63035 ? 113 ASN B CG  1 
ATOM   1930 O OD1 . ASN B 1 113 ? 27.70339 -12.51008 42.67330  1.000 17.24487 ? 113 ASN B OD1 1 
ATOM   1931 N ND2 . ASN B 1 113 ? 27.68536 -13.04296 44.85048  1.000 24.16830 ? 113 ASN B ND2 1 
ATOM   1932 N N   . GLU B 1 114 ? 32.15413 -10.87817 44.61206  1.000 18.98172 ? 114 GLU B N   1 
ATOM   1933 C CA  . GLU B 1 114 ? 33.48025 -10.49858 45.08069  1.000 18.16676 ? 114 GLU B CA  1 
ATOM   1934 C C   . GLU B 1 114 ? 33.93581 -9.20230  44.42788  1.000 16.95029 ? 114 GLU B C   1 
ATOM   1935 O O   . GLU B 1 114 ? 33.69362 -8.97418  43.24064  1.000 17.44387 ? 114 GLU B O   1 
ATOM   1936 C CB  . GLU B 1 114 ? 34.50081 -11.58615 44.75233  1.000 18.06469 ? 114 GLU B CB  1 
ATOM   1937 C CG  . GLU B 1 114 ? 34.27393 -12.91745 45.47163  1.000 21.29519 ? 114 GLU B CG  1 
ATOM   1938 C CD  . GLU B 1 114 ? 34.40377 -12.83195 46.98137  1.000 24.57729 ? 114 GLU B CD  1 
ATOM   1939 O OE1 . GLU B 1 114 ? 34.99456 -11.86463 47.50427  1.000 25.53190 ? 114 GLU B OE1 1 
ATOM   1940 O OE2 . GLU B 1 114 ? 33.91552 -13.75886 47.66936  1.000 28.52092 ? 114 GLU B OE2 1 
ATOM   1941 N N   . ILE B 1 115 ? 34.60066 -8.35761  45.22016  1.000 17.19720 ? 115 ILE B N   1 
ATOM   1942 C CA  . ILE B 1 115 ? 35.24576 -7.13804  44.74050  1.000 16.59094 ? 115 ILE B CA  1 
ATOM   1943 C C   . ILE B 1 115 ? 36.70522 -7.16949  45.17658  1.000 17.06061 ? 115 ILE B C   1 
ATOM   1944 O O   . ILE B 1 115 ? 37.02123 -7.59395  46.29292  1.000 17.89163 ? 115 ILE B O   1 
ATOM   1945 C CB  . ILE B 1 115 ? 34.54822 -5.87918  45.30336  1.000 16.30788 ? 115 ILE B CB  1 
ATOM   1946 C CG1 . ILE B 1 115 ? 33.14696 -5.73317  44.70532  1.000 16.48780 ? 115 ILE B CG1 1 
ATOM   1947 C CG2 . ILE B 1 115 ? 35.37491 -4.62820  45.01694  1.000 16.01017 ? 115 ILE B CG2 1 
ATOM   1948 C CD1 . ILE B 1 115 ? 32.44423 -4.42299  45.07883  1.000 16.24721 ? 115 ILE B CD1 1 
ATOM   1949 N N   . ILE B 1 116 ? 37.59829 -6.73085  44.29148  1.000 14.58177 ? 116 ILE B N   1 
ATOM   1950 C CA  . ILE B 1 116 ? 38.98395 -6.42938  44.63212  1.000 15.39608 ? 116 ILE B CA  1 
ATOM   1951 C C   . ILE B 1 116 ? 39.13701 -4.91141  44.66213  1.000 14.97668 ? 116 ILE B C   1 
ATOM   1952 O O   . ILE B 1 116 ? 38.57683 -4.20888  43.81236  1.000 16.47585 ? 116 ILE B O   1 
ATOM   1953 C CB  . ILE B 1 116 ? 39.93470 -7.07237  43.60566  1.000 15.63663 ? 116 ILE B CB  1 
ATOM   1954 C CG1 . ILE B 1 116 ? 39.88280 -8.59280  43.72383  1.000 19.29989 ? 116 ILE B CG1 1 
ATOM   1955 C CG2 . ILE B 1 116 ? 41.34593 -6.57951  43.80847  1.000 18.38531 ? 116 ILE B CG2 1 
ATOM   1956 C CD1 . ILE B 1 116 ? 40.77872 -9.30474  42.71925  1.000 17.79382 ? 116 ILE B CD1 1 
ATOM   1957 N N   . SER B 1 117 ? 39.86462 -4.40736  45.65541  1.000 14.56841 ? 117 SER B N   1 
ATOM   1958 C CA  . SER B 1 117 ? 39.88945 -2.98301  45.95719  1.000 14.77666 ? 117 SER B CA  1 
ATOM   1959 C C   . SER B 1 117 ? 41.30700 -2.47881  46.19894  1.000 15.91157 ? 117 SER B C   1 
ATOM   1960 O O   . SER B 1 117 ? 42.22266 -3.24659  46.50367  1.000 18.77836 ? 117 SER B O   1 
ATOM   1961 C CB  . SER B 1 117 ? 39.10900 -2.69759  47.24924  1.000 18.55198 ? 117 SER B CB  1 
ATOM   1962 O OG  . SER B 1 117 ? 37.73731 -3.02504  47.10042  1.000 19.60925 ? 117 SER B OG  1 
ATOM   1963 N N   . MET B 1 118 ? 41.46376 -1.15711  46.09718  1.000 16.34206 ? 118 MET B N   1 
ATOM   1964 C CA  . MET B 1 118 ? 42.57096 -0.43372  46.71695  1.000 17.23757 ? 118 MET B CA  1 
ATOM   1965 C C   . MET B 1 118 ? 42.11720 0.12419   48.06221  1.000 18.35665 ? 118 MET B C   1 
ATOM   1966 O O   . MET B 1 118 ? 40.92034 0.25546   48.31999  1.000 17.37662 ? 118 MET B O   1 
ATOM   1967 C CB  . MET B 1 118 ? 43.08641 0.68820   45.81155  1.000 17.26243 ? 118 MET B CB  1 
ATOM   1968 C CG  . MET B 1 118 ? 43.07593 0.32579   44.35400  1.000 21.28214 ? 118 MET B CG  1 
ATOM   1969 S SD  . MET B 1 118 ? 43.43980 1.70302   43.25853  0.607 23.43898 ? 118 MET B SD  1 
ATOM   1970 C CE  . MET B 1 118 ? 42.00145 2.73153   43.42951  1.000 25.81019 ? 118 MET B CE  1 
ATOM   1971 N N   . VAL B 1 119 ? 43.07880 0.42549   48.93759  1.000 17.29673 ? 119 VAL B N   1 
ATOM   1972 C CA  . VAL B 1 119 ? 42.78188 0.66192   50.35029  1.000 17.55017 ? 119 VAL B CA  1 
ATOM   1973 C C   . VAL B 1 119 ? 43.22202 2.05923   50.77569  1.000 18.58427 ? 119 VAL B C   1 
ATOM   1974 O O   . VAL B 1 119 ? 44.34160 2.48531   50.47739  1.000 18.65958 ? 119 VAL B O   1 
ATOM   1975 C CB  . VAL B 1 119 ? 43.41309 -0.41950  51.24675  1.000 21.85764 ? 119 VAL B CB  1 
ATOM   1976 C CG1 . VAL B 1 119 ? 42.81379 -1.77985  50.91131  1.000 24.31436 ? 119 VAL B CG1 1 
ATOM   1977 C CG2 . VAL B 1 119 ? 44.91245 -0.44598  51.07546  1.000 23.51322 ? 119 VAL B CG2 1 
ATOM   1978 N N   . GLY B 1 120 ? 42.34795 2.75439   51.50733  1.000 17.33642 ? 120 GLY B N   1 
ATOM   1979 C CA  . GLY B 1 120 ? 42.64456 4.05352   52.04927  1.000 19.03931 ? 120 GLY B CA  1 
ATOM   1980 C C   . GLY B 1 120 ? 42.88319 4.01485   53.54483  1.000 23.53178 ? 120 GLY B C   1 
ATOM   1981 O O   . GLY B 1 120 ? 43.13678 2.95938   54.14104  1.000 24.39716 ? 120 GLY B O   1 
ATOM   1982 N N   . SER B 1 121 ? 42.79717 5.18566   54.16642  1.000 23.59441 ? 121 SER B N   1 
ATOM   1983 C CA  . SER B 1 121 ? 42.89214 5.26234   55.61524  1.000 23.20367 ? 121 SER B CA  1 
ATOM   1984 C C   . SER B 1 121 ? 41.63669 4.67534   56.25270  1.000 27.67583 ? 121 SER B C   1 
ATOM   1985 O O   . SER B 1 121 ? 40.56244 4.64655   55.64806  1.000 27.69771 ? 121 SER B O   1 
ATOM   1986 C CB  . SER B 1 121 ? 43.04889 6.72330   56.03969  1.000 26.34679 ? 121 SER B CB  1 
ATOM   1987 O OG  . SER B 1 121 ? 41.91248 7.48086   55.66040  1.000 27.03656 ? 121 SER B OG  1 
ATOM   1988 N N   . GLY B 1 122 ? 41.77905 4.19513   57.48606  1.000 27.15175 ? 122 GLY B N   1 
ATOM   1989 C CA  . GLY B 1 122 ? 40.60374 3.73663   58.21485  1.000 28.42030 ? 122 GLY B CA  1 
ATOM   1990 C C   . GLY B 1 122 ? 39.91693 2.60135   57.48459  1.000 29.62337 ? 122 GLY B C   1 
ATOM   1991 O O   . GLY B 1 122 ? 40.54396 1.59886   57.12058  1.000 31.82299 ? 122 GLY B O   1 
ATOM   1992 N N   . SER B 1 123 ? 38.61522 2.76247   57.24652  1.000 26.92578 ? 123 SER B N   1 
ATOM   1993 C CA  . SER B 1 123 ? 37.81595 1.76641   56.54498  1.000 27.99783 ? 123 SER B CA  1 
ATOM   1994 C C   . SER B 1 123 ? 37.62387 2.09252   55.06836  1.000 27.29834 ? 123 SER B C   1 
ATOM   1995 O O   . SER B 1 123 ? 36.80053 1.45359   54.40907  1.000 30.13871 ? 123 SER B O   1 
ATOM   1996 C CB  . SER B 1 123 ? 36.44939 1.59374   57.21522  1.000 30.68652 ? 123 SER B CB  1 
ATOM   1997 O OG  . SER B 1 123 ? 35.70414 2.79513   57.18045  1.000 35.67150 ? 123 SER B OG  1 
ATOM   1998 N N   . ILE B 1 124 ? 38.36038 3.06552   54.53391  1.000 21.95403 ? 124 ILE B N   1 
ATOM   1999 C CA  . ILE B 1 124 ? 38.17261 3.46687   53.14425  1.000 19.90164 ? 124 ILE B CA  1 
ATOM   2000 C C   . ILE B 1 124 ? 38.73134 2.39510   52.21587  1.000 19.96413 ? 124 ILE B C   1 
ATOM   2001 O O   . ILE B 1 124 ? 39.84411 1.88836   52.42197  1.000 18.87093 ? 124 ILE B O   1 
ATOM   2002 C CB  . ILE B 1 124 ? 38.84367 4.82345   52.89190  1.000 18.13775 ? 124 ILE B CB  1 
ATOM   2003 C CG1 . ILE B 1 124 ? 38.09754 5.91617   53.64736  1.000 19.02609 ? 124 ILE B CG1 1 
ATOM   2004 C CG2 . ILE B 1 124 ? 38.89579 5.12178   51.40104  1.000 20.00402 ? 124 ILE B CG2 1 
ATOM   2005 C CD1 . ILE B 1 124 ? 38.84805 7.24209   53.69254  1.000 23.57033 ? 124 ILE B CD1 1 
ATOM   2006 N N   . ALA B 1 125 ? 37.94991 2.03574   51.19518  1.000 19.54887 ? 125 ALA B N   1 
ATOM   2007 C CA  . ALA B 1 125 ? 38.37484 1.08975   50.17235  1.000 20.68918 ? 125 ALA B CA  1 
ATOM   2008 C C   . ALA B 1 125 ? 37.66254 1.42538   48.86948  1.000 19.04391 ? 125 ALA B C   1 
ATOM   2009 O O   . ALA B 1 125 ? 36.48330 1.78271   48.87718  1.000 18.42512 ? 125 ALA B O   1 
ATOM   2010 C CB  . ALA B 1 125 ? 38.09085 -0.35740  50.58916  1.000 21.23283 ? 125 ALA B CB  1 
ATOM   2011 N N   . ALA B 1 126 ? 38.38272 1.31960   47.75505  1.000 16.71779 ? 126 ALA B N   1 
ATOM   2012 C CA  . ALA B 1 126 ? 37.88986 1.72652   46.44226  1.000 17.78644 ? 126 ALA B CA  1 
ATOM   2013 C C   . ALA B 1 126 ? 37.83639 0.51267   45.52447  1.000 14.41017 ? 126 ALA B C   1 
ATOM   2014 O O   . ALA B 1 126 ? 38.86840 -0.12296  45.27977  1.000 16.66445 ? 126 ALA B O   1 
ATOM   2015 C CB  . ALA B 1 126 ? 38.81529 2.78970   45.84148  1.000 18.59460 ? 126 ALA B CB  1 
ATOM   2016 N N   . ALA B 1 127 ? 36.64647 0.19642   45.01234  1.000 13.94655 ? 127 ALA B N   1 
ATOM   2017 C CA  . ALA B 1 127 ? 36.47832 -0.98655  44.17236  1.000 15.53903 ? 127 ALA B CA  1 
ATOM   2018 C C   . ALA B 1 127 ? 37.21087 -0.82086  42.84564  1.000 16.21250 ? 127 ALA B C   1 
ATOM   2019 O O   . ALA B 1 127 ? 37.01565 0.16974   42.14113  1.000 17.89808 ? 127 ALA B O   1 
ATOM   2020 C CB  . ALA B 1 127 ? 34.99881 -1.21407  43.89115  1.000 15.57189 ? 127 ALA B CB  1 
ATOM   2021 N N   . THR B 1 128 ? 38.01620 -1.82098  42.47334  1.000 13.92986 ? 128 THR B N   1 
ATOM   2022 C CA  . THR B 1 128 ? 38.72151 -1.80482  41.19291  1.000 15.04296 ? 128 THR B CA  1 
ATOM   2023 C C   . THR B 1 128 ? 38.35935 -2.95955  40.26450  1.000 14.12272 ? 128 THR B C   1 
ATOM   2024 O O   . THR B 1 128 ? 38.46389 -2.81589  39.04636  1.000 14.91313 ? 128 THR B O   1 
ATOM   2025 C CB  . THR B 1 128 ? 40.23646 -1.78948  41.40682  1.000 19.84235 ? 128 THR B CB  1 
ATOM   2026 O OG1 . THR B 1 128 ? 40.61790 -2.96617  42.12670  1.000 25.03688 ? 128 THR B OG1 1 
ATOM   2027 C CG2 . THR B 1 128 ? 40.60626 -0.57454  42.22798  1.000 19.84472 ? 128 THR B CG2 1 
ATOM   2028 N N   . MET B 1 129 ? 37.96958 -4.11390  40.79946  1.000 14.56946 ? 129 MET B N   1 
ATOM   2029 C CA  . MET B 1 129 ? 37.37785 -5.17991  40.00771  1.000 13.91353 ? 129 MET B CA  1 
ATOM   2030 C C   . MET B 1 129 ? 36.10967 -5.58707  40.73571  1.000 14.34910 ? 129 MET B C   1 
ATOM   2031 O O   . MET B 1 129 ? 36.13794 -5.78113  41.95477  1.000 16.49782 ? 129 MET B O   1 
ATOM   2032 C CB  . MET B 1 129 ? 38.32141 -6.38478  39.87718  1.000 16.65220 ? 129 MET B CB  1 
ATOM   2033 C CG  . MET B 1 129 ? 39.51466 -6.12503  38.97037  1.000 15.20354 ? 129 MET B CG  1 
ATOM   2034 S SD  . MET B 1 129 ? 40.58326 -7.58420  38.87265  0.979 17.35462 ? 129 MET B SD  1 
ATOM   2035 C CE  . MET B 1 129 ? 39.50630 -8.69559  37.97279  1.000 18.27578 ? 129 MET B CE  1 
ATOM   2036 N N   . VAL B 1 130 ? 35.00591 -5.68495  40.00072  1.000 12.92938 ? 130 VAL B N   1 
ATOM   2037 C CA  . VAL B 1 130 ? 33.70900 -6.03174  40.57783  1.000 15.60186 ? 130 VAL B CA  1 
ATOM   2038 C C   . VAL B 1 130 ? 33.12667 -7.18060  39.76998  1.000 14.30591 ? 130 VAL B C   1 
ATOM   2039 O O   . VAL B 1 130 ? 33.10229 -7.12538  38.53511  1.000 14.82827 ? 130 VAL B O   1 
ATOM   2040 C CB  . VAL B 1 130 ? 32.74319 -4.83104  40.58473  1.000 14.28945 ? 130 VAL B CB  1 
ATOM   2041 C CG1 . VAL B 1 130 ? 31.44123 -5.22688  41.25317  1.000 17.33617 ? 130 VAL B CG1 1 
ATOM   2042 C CG2 . VAL B 1 130 ? 33.35486 -3.62860  41.31136  1.000 17.13391 ? 130 VAL B CG2 1 
ATOM   2043 N N   . SER B 1 131 ? 32.65542 -8.22324  40.45890  1.000 15.50832 ? 131 SER B N   1 
ATOM   2044 C CA  . SER B 1 131 ? 32.12283 -9.40093  39.79221  1.000 15.91262 ? 131 SER B CA  1 
ATOM   2045 C C   . SER B 1 131 ? 30.67692 -9.67393  40.18744  1.000 14.20536 ? 131 SER B C   1 
ATOM   2046 O O   . SER B 1 131 ? 30.23680 -9.31935  41.28872  1.000 17.15707 ? 131 SER B O   1 
ATOM   2047 C CB  . SER B 1 131 ? 32.97735 -10.64105 40.08624  1.000 17.08188 ? 131 SER B CB  1 
ATOM   2048 O OG  . SER B 1 131 ? 32.90683 -11.01801 41.45490  1.000 18.18711 ? 131 SER B OG  1 
ATOM   2049 N N   . TRP B 1 132 ? 29.95256 -10.29109 39.25416  1.000 15.24606 ? 132 TRP B N   1 
ATOM   2050 C CA  . TRP B 1 132 ? 28.60617 -10.82281 39.47382  1.000 15.68232 ? 132 TRP B CA  1 
ATOM   2051 C C   . TRP B 1 132 ? 28.62497 -12.26322 38.98755  1.000 14.89381 ? 132 TRP B C   1 
ATOM   2052 O O   . TRP B 1 132 ? 28.83991 -12.51459 37.79926  1.000 18.41207 ? 132 TRP B O   1 
ATOM   2053 C CB  . TRP B 1 132 ? 27.55739 -10.02195 38.69405  1.000 16.76358 ? 132 TRP B CB  1 
ATOM   2054 C CG  . TRP B 1 132 ? 27.41715 -8.59692  39.13261  1.000 17.66230 ? 132 TRP B CG  1 
ATOM   2055 C CD1 . TRP B 1 132 ? 26.48012 -8.07658  40.00106  1.000 17.86905 ? 132 TRP B CD1 1 
ATOM   2056 C CD2 . TRP B 1 132 ? 28.22504 -7.49566  38.70965  1.000 16.81460 ? 132 TRP B CD2 1 
ATOM   2057 N NE1 . TRP B 1 132 ? 26.68049 -6.72582  40.15275  1.000 18.46800 ? 132 TRP B NE1 1 
ATOM   2058 C CE2 . TRP B 1 132 ? 27.73530 -6.34002  39.36044  1.000 16.03625 ? 132 TRP B CE2 1 
ATOM   2059 C CE3 . TRP B 1 132 ? 29.31651 -7.37068  37.83779  1.000 17.11521 ? 132 TRP B CE3 1 
ATOM   2060 C CZ2 . TRP B 1 132 ? 28.31246 -5.08496  39.17614  1.000 16.74156 ? 132 TRP B CZ2 1 
ATOM   2061 C CZ3 . TRP B 1 132 ? 29.88090 -6.11743  37.65642  1.000 16.01524 ? 132 TRP B CZ3 1 
ATOM   2062 C CH2 . TRP B 1 132 ? 29.36751 -4.99206  38.31880  1.000 19.29445 ? 132 TRP B CH2 1 
ATOM   2063 N N   . LYS B 1 133 ? 28.39808 -13.20915 39.89850  1.000 16.23105 ? 133 LYS B N   1 
ATOM   2064 C CA  . LYS B 1 133 ? 28.63476 -14.60760 39.56121  1.000 17.41506 ? 133 LYS B CA  1 
ATOM   2065 C C   . LYS B 1 133 ? 27.68346 -15.13719 38.49218  1.000 17.78467 ? 133 LYS B C   1 
ATOM   2066 O O   . LYS B 1 133 ? 28.04140 -16.06228 37.74908  1.000 18.86035 ? 133 LYS B O   1 
ATOM   2067 C CB  . LYS B 1 133 ? 28.59653 -15.48003 40.82161  1.000 17.72539 ? 133 LYS B CB  1 
ATOM   2068 C CG  . LYS B 1 133 ? 29.78979 -15.29234 41.75821  1.000 22.82102 ? 133 LYS B CG  1 
ATOM   2069 C CD  . LYS B 1 133 ? 29.58584 -16.00645 43.09174  1.000 25.42320 ? 133 LYS B CD  1 
ATOM   2070 C CE  . LYS B 1 133 ? 30.88219 -16.02818 43.90130  1.000 28.21800 ? 133 LYS B CE  1 
ATOM   2071 N NZ  . LYS B 1 133 ? 30.73413 -16.77954 45.18697  1.000 32.35034 ? 133 LYS B NZ  1 
ATOM   2072 N N   . SER B 1 134 ? 26.46675 -14.59656 38.40127  1.000 17.90532 ? 134 SER B N   1 
ATOM   2073 C CA  . SER B 1 134 ? 25.44537 -15.19819 37.54897  1.000 17.69938 ? 134 SER B CA  1 
ATOM   2074 C C   . SER B 1 134 ? 24.71253 -14.17800 36.68280  1.000 19.69812 ? 134 SER B C   1 
ATOM   2075 O O   . SER B 1 134 ? 23.65896 -14.49420 36.12889  1.000 23.11180 ? 134 SER B O   1 
ATOM   2076 C CB  . SER B 1 134 ? 24.44785 -16.02641 38.37852  1.000 16.62802 ? 134 SER B CB  1 
ATOM   2077 O OG  . SER B 1 134 ? 25.10796 -17.12297 38.99910  1.000 19.03302 ? 134 SER B OG  1 
ATOM   2078 N N   . THR B 1 135 ? 25.25071 -12.97165 36.53464  1.000 17.92493 ? 135 THR B N   1 
ATOM   2079 C CA  . THR B 1 135 ? 24.61841 -11.92018 35.75439  1.000 18.31590 ? 135 THR B CA  1 
ATOM   2080 C C   . THR B 1 135 ? 25.56919 -11.50431 34.64307  1.000 19.34224 ? 135 THR B C   1 
ATOM   2081 O O   . THR B 1 135 ? 26.76262 -11.31136 34.89274  1.000 20.21917 ? 135 THR B O   1 
ATOM   2082 C CB  . THR B 1 135 ? 24.30932 -10.73153 36.66095  1.000 18.93843 ? 135 THR B CB  1 
ATOM   2083 O OG1 . THR B 1 135 ? 23.54092 -11.19523 37.78084  1.000 18.49282 ? 135 THR B OG1 1 
ATOM   2084 C CG2 . THR B 1 135 ? 23.53794 -9.65547  35.89687  1.000 21.15037 ? 135 THR B CG2 1 
ATOM   2085 N N   . LYS B 1 136 ? 25.04896 -11.37801 33.42776  1.000 18.89424 ? 136 LYS B N   1 
ATOM   2086 C CA  . LYS B 1 136 ? 25.85231 -11.02360 32.26587  1.000 17.77907 ? 136 LYS B CA  1 
ATOM   2087 C C   . LYS B 1 136 ? 25.71189 -9.54508  31.92024  1.000 20.63364 ? 136 LYS B C   1 
ATOM   2088 O O   . LYS B 1 136 ? 24.66467 -8.92317  32.12634  1.000 22.86921 ? 136 LYS B O   1 
ATOM   2089 C CB  . LYS B 1 136 ? 25.45974 -11.85476 31.04119  1.000 19.00446 ? 136 LYS B CB  1 
ATOM   2090 C CG  . LYS B 1 136 ? 25.74618 -13.34535 31.14182  1.000 20.36187 ? 136 LYS B CG  1 
ATOM   2091 C CD  . LYS B 1 136 ? 27.20206 -13.65729 30.79972  1.000 22.31909 ? 136 LYS B CD  1 
ATOM   2092 C CE  . LYS B 1 136 ? 27.58907 -15.05626 31.24741  1.000 23.04798 ? 136 LYS B CE  1 
ATOM   2093 N NZ  . LYS B 1 136 ? 29.07500 -15.22362 31.25303  1.000 19.71389 ? 136 LYS B NZ  1 
ATOM   2094 N N   . ALA B 1 137 ? 26.79654 -8.98843  31.38516  1.000 17.97038 ? 137 ALA B N   1 
ATOM   2095 C CA  . ALA B 1 137 ? 26.75770 -7.67019  30.77789  1.000 18.02612 ? 137 ALA B CA  1 
ATOM   2096 C C   . ALA B 1 137 ? 26.15449 -7.77197  29.38144  1.000 20.86230 ? 137 ALA B C   1 
ATOM   2097 O O   . ALA B 1 137 ? 26.45230 -8.70359  28.62790  1.000 21.26922 ? 137 ALA B O   1 
ATOM   2098 C CB  . ALA B 1 137 ? 28.17932 -7.12295  30.66963  1.000 19.69610 ? 137 ALA B CB  1 
ATOM   2099 N N   . ALA B 1 138 ? 25.30266 -6.80779  29.04339  1.000 18.76679 ? 138 ALA B N   1 
ATOM   2100 C CA  . ALA B 1 138 ? 24.65489 -6.74412  27.73982  1.000 20.04158 ? 138 ALA B CA  1 
ATOM   2101 C C   . ALA B 1 138 ? 24.20060 -5.30895  27.52461  1.000 21.65851 ? 138 ALA B C   1 
ATOM   2102 O O   . ALA B 1 138 ? 24.03846 -4.54638  28.47926  1.000 20.88945 ? 138 ALA B O   1 
ATOM   2103 C CB  . ALA B 1 138 ? 23.45447 -7.69585  27.66108  1.000 21.76878 ? 138 ALA B CB  1 
ATOM   2104 N N   . ALA B 1 139 ? 24.00882 -4.94218  26.26067  1.000 22.54641 ? 139 ALA B N   1 
ATOM   2105 C CA  . ALA B 1 139 ? 23.61352 -3.57418  25.95792  1.000 22.91096 ? 139 ALA B CA  1 
ATOM   2106 C C   . ALA B 1 139 ? 22.23472 -3.28772  26.53913  1.000 20.93171 ? 139 ALA B C   1 
ATOM   2107 O O   . ALA B 1 139 ? 21.32594 -4.12261  26.47154  1.000 23.20226 ? 139 ALA B O   1 
ATOM   2108 C CB  . ALA B 1 139 ? 23.60822 -3.33822  24.44840  1.000 24.34611 ? 139 ALA B CB  1 
ATOM   2109 N N   . GLY B 1 140 ? 22.09047 -2.10261  27.13440  1.000 22.90505 ? 140 GLY B N   1 
ATOM   2110 C CA  . GLY B 1 140 ? 20.82632 -1.65042  27.68724  1.000 23.32127 ? 140 GLY B CA  1 
ATOM   2111 C C   . GLY B 1 140 ? 20.55371 -2.07014  29.11849  1.000 24.22242 ? 140 GLY B C   1 
ATOM   2112 O O   . GLY B 1 140 ? 19.59238 -1.56866  29.72226  1.000 23.87623 ? 140 GLY B O   1 
ATOM   2113 N N   . ILE B 1 141 ? 21.36470 -2.97411  29.67166  1.000 23.35549 ? 141 ILE B N   1 
ATOM   2114 C CA  . ILE B 1 141 ? 21.23123 -3.41051  31.05702  1.000 24.26672 ? 141 ILE B CA  1 
ATOM   2115 C C   . ILE B 1 141 ? 21.59333 -2.25759  31.98770  1.000 21.37117 ? 141 ILE B C   1 
ATOM   2116 O O   . ILE B 1 141 ? 22.50178 -1.46732  31.69766  1.000 20.98733 ? 141 ILE B O   1 
ATOM   2117 C CB  . ILE B 1 141 ? 22.18089 -4.60698  31.26424  1.000 23.23354 ? 141 ILE B CB  1 
ATOM   2118 C CG1 . ILE B 1 141 ? 21.67574 -5.82981  30.49185  1.000 26.96064 ? 141 ILE B CG1 1 
ATOM   2119 C CG2 . ILE B 1 141 ? 22.38621 -4.93115  32.73745  1.000 26.61515 ? 141 ILE B CG2 1 
ATOM   2120 C CD1 . ILE B 1 141 ? 20.21262 -6.10834  30.68395  1.000 27.85776 ? 141 ILE B CD1 1 
ATOM   2121 N N   . SER B 1 142 ? 20.89215 -2.15125  33.11479  1.000 22.27747 ? 142 SER B N   1 
ATOM   2122 C CA  . SER B 1 142 ? 21.16226 -1.07611  34.06106  1.000 20.88668 ? 142 SER B CA  1 
ATOM   2123 C C   . SER B 1 142 ? 22.42828 -1.34760  34.86739  1.000 22.33893 ? 142 SER B C   1 
ATOM   2124 O O   . SER B 1 142 ? 22.77636 -2.49543  35.15590  1.000 19.40337 ? 142 SER B O   1 
ATOM   2125 C CB  . SER B 1 142 ? 20.00531 -0.90336  35.04444  1.000 22.77351 ? 142 SER B CB  1 
ATOM   2126 O OG  . SER B 1 142 ? 19.89505 -2.02991  35.89451  1.000 25.43837 ? 142 SER B OG  1 
ATOM   2127 N N   . PHE B 1 143 ? 23.11301 -0.26179  35.23381  1.000 20.78045 ? 143 PHE B N   1 
ATOM   2128 C CA  . PHE B 1 143 ? 24.22061 -0.27386  36.17836  1.000 20.57642 ? 143 PHE B CA  1 
ATOM   2129 C C   . PHE B 1 143 ? 23.94761 0.82192   37.20019  1.000 20.10005 ? 143 PHE B C   1 
ATOM   2130 O O   . PHE B 1 143 ? 23.81866 1.99867   36.83612  1.000 22.00934 ? 143 PHE B O   1 
ATOM   2131 C CB  . PHE B 1 143 ? 25.54562 -0.01801  35.45211  1.000 20.26024 ? 143 PHE B CB  1 
ATOM   2132 C CG  . PHE B 1 143 ? 26.74335 -0.00211  36.35538  1.000 16.78085 ? 143 PHE B CG  1 
ATOM   2133 C CD1 . PHE B 1 143 ? 27.25972 -1.17509  36.88655  1.000 18.73927 ? 143 PHE B CD1 1 
ATOM   2134 C CD2 . PHE B 1 143 ? 27.36662 1.19490   36.66753  1.000 19.08299 ? 143 PHE B CD2 1 
ATOM   2135 C CE1 . PHE B 1 143 ? 28.36626 -1.14490  37.70928  1.000 17.97769 ? 143 PHE B CE1 1 
ATOM   2136 C CE2 . PHE B 1 143 ? 28.46977 1.22697   37.49054  1.000 17.36487 ? 143 PHE B CE2 1 
ATOM   2137 C CZ  . PHE B 1 143 ? 28.96695 0.05977   38.01796  1.000 15.10485 ? 143 PHE B CZ  1 
ATOM   2138 N N   . LYS B 1 144 ? 23.81438 0.43599   38.46595  1.000 18.24683 ? 144 LYS B N   1 
ATOM   2139 C CA  . LYS B 1 144 ? 23.48321 1.35861   39.54232  1.000 18.79768 ? 144 LYS B CA  1 
ATOM   2140 C C   . LYS B 1 144 ? 24.60652 1.29773   40.56371  1.000 18.83420 ? 144 LYS B C   1 
ATOM   2141 O O   . LYS B 1 144 ? 24.98807 0.20840   41.00189  1.000 18.75888 ? 144 LYS B O   1 
ATOM   2142 C CB  . LYS B 1 144 ? 22.15596 0.95514   40.18922  1.000 18.72383 ? 144 LYS B CB  1 
ATOM   2143 C CG  . LYS B 1 144 ? 20.99098 1.07107   39.23596  1.000 22.43602 ? 144 LYS B CG  1 
ATOM   2144 C CD  . LYS B 1 144 ? 19.70940 0.53631   39.85598  1.000 27.02946 ? 144 LYS B CD  1 
ATOM   2145 C CE  . LYS B 1 144 ? 18.78329 0.01798   38.77305  1.000 28.56835 ? 144 LYS B CE  1 
ATOM   2146 N NZ  . LYS B 1 144 ? 17.93831 1.12482   38.24464  1.000 35.68272 ? 144 LYS B NZ  1 
ATOM   2147 N N   . TYR B 1 145 ? 25.14319 2.45988   40.93626  1.000 15.95098 ? 145 TYR B N   1 
ATOM   2148 C CA  . TYR B 1 145 ? 26.34867 2.48390   41.74789  1.000 16.60123 ? 145 TYR B CA  1 
ATOM   2149 C C   . TYR B 1 145 ? 26.29999 3.65113   42.72242  1.000 15.22852 ? 145 TYR B C   1 
ATOM   2150 O O   . TYR B 1 145 ? 25.55419 4.62166   42.53867  1.000 16.73875 ? 145 TYR B O   1 
ATOM   2151 C CB  . TYR B 1 145 ? 27.61791 2.61655   40.88436  1.000 16.01201 ? 145 TYR B CB  1 
ATOM   2152 C CG  . TYR B 1 145 ? 27.74065 3.98026   40.24030  1.000 15.48098 ? 145 TYR B CG  1 
ATOM   2153 C CD1 . TYR B 1 145 ? 27.11880 4.26588   39.02911  1.000 15.19438 ? 145 TYR B CD1 1 
ATOM   2154 C CD2 . TYR B 1 145 ? 28.44774 4.99706   40.86770  1.000 16.78682 ? 145 TYR B CD2 1 
ATOM   2155 C CE1 . TYR B 1 145 ? 27.20545 5.53081   38.45959  1.000 17.14093 ? 145 TYR B CE1 1 
ATOM   2156 C CE2 . TYR B 1 145 ? 28.53066 6.26041   40.30854  1.000 16.76517 ? 145 TYR B CE2 1 
ATOM   2157 C CZ  . TYR B 1 145 ? 27.91902 6.51431   39.10611  1.000 17.67151 ? 145 TYR B CZ  1 
ATOM   2158 O OH  . TYR B 1 145 ? 28.00464 7.76891   38.55013  1.000 21.04934 ? 145 TYR B OH  1 
ATOM   2159 N N   . LEU B 1 146 ? 27.12288 3.54514   43.76031  1.000 16.63881 ? 146 LEU B N   1 
ATOM   2160 C CA  . LEU B 1 146 ? 27.36192 4.63365   44.69662  1.000 15.89403 ? 146 LEU B CA  1 
ATOM   2161 C C   . LEU B 1 146 ? 28.84252 4.98063   44.62510  1.000 16.03308 ? 146 LEU B C   1 
ATOM   2162 O O   . LEU B 1 146 ? 29.69615 4.12877   44.88975  1.000 16.19060 ? 146 LEU B O   1 
ATOM   2163 C CB  . LEU B 1 146 ? 26.99106 4.21648   46.12216  1.000 17.32714 ? 146 LEU B CB  1 
ATOM   2164 C CG  . LEU B 1 146 ? 26.73548 5.37265   47.08571  1.000 20.78526 ? 146 LEU B CG  1 
ATOM   2165 C CD1 . LEU B 1 146 ? 25.54214 6.20981   46.61979  1.000 20.52196 ? 146 LEU B CD1 1 
ATOM   2166 C CD2 . LEU B 1 146 ? 26.57216 4.91203   48.53216  1.000 28.59619 ? 146 LEU B CD2 1 
ATOM   2167 N N   . GLY B 1 147 ? 29.14543 6.21770   44.25803  1.000 15.66823 ? 147 GLY B N   1 
ATOM   2168 C CA  . GLY B 1 147 ? 30.50340 6.72337   44.28738  1.000 15.41570 ? 147 GLY B CA  1 
ATOM   2169 C C   . GLY B 1 147 ? 30.75911 7.54788   45.53659  1.000 18.98986 ? 147 GLY B C   1 
ATOM   2170 O O   . GLY B 1 147 ? 29.83962 8.12500   46.11185  1.000 16.89370 ? 147 GLY B O   1 
ATOM   2171 N N   . LYS B 1 148 ? 32.01749 7.58722   45.96818  1.000 15.56366 ? 148 LYS B N   1 
ATOM   2172 C CA  . LYS B 1 148 ? 32.41047 8.36119   47.13749  1.000 13.91934 ? 148 LYS B CA  1 
ATOM   2173 C C   . LYS B 1 148 ? 33.64278 9.18615   46.79703  1.000 15.27285 ? 148 LYS B C   1 
ATOM   2174 O O   . LYS B 1 148 ? 34.24709 9.01910   45.74335  1.000 15.11830 ? 148 LYS B O   1 
ATOM   2175 C CB  . LYS B 1 148 ? 32.67544 7.46032   48.35512  1.000 17.43714 ? 148 LYS B CB  1 
ATOM   2176 C CG  . LYS B 1 148 ? 31.36556 7.01918   49.04378  1.000 20.19310 ? 148 LYS B CG  1 
ATOM   2177 C CD  . LYS B 1 148 ? 31.52947 5.69967   49.75311  1.000 24.52567 ? 148 LYS B CD  1 
ATOM   2178 C CE  . LYS B 1 148 ? 30.21441 5.26559   50.40426  1.000 29.27145 ? 148 LYS B CE  1 
ATOM   2179 N NZ  . LYS B 1 148 ? 29.49053 6.38627   51.07210  1.000 28.82542 ? 148 LYS B NZ  1 
ATOM   2180 N N   . ASN B 1 149 ? 34.01070 10.09520  47.69449  1.000 15.08669 ? 149 ASN B N   1 
ATOM   2181 C CA  . ASN B 1 149 ? 35.18985 10.92058  47.46639  1.000 14.77457 ? 149 ASN B CA  1 
ATOM   2182 C C   . ASN B 1 149 ? 35.92473 11.14530  48.77934  1.000 16.24379 ? 149 ASN B C   1 
ATOM   2183 O O   . ASN B 1 149 ? 35.43381 10.81696  49.86432  1.000 16.48171 ? 149 ASN B O   1 
ATOM   2184 C CB  . ASN B 1 149 ? 34.84915 12.23287  46.74392  1.000 13.73356 ? 149 ASN B CB  1 
ATOM   2185 C CG  . ASN B 1 149 ? 34.26202 13.27569  47.67490  1.000 15.01618 ? 149 ASN B CG  1 
ATOM   2186 O OD1 . ASN B 1 149 ? 34.99233 14.09829  48.23165  1.000 15.26932 ? 149 ASN B OD1 1 
ATOM   2187 N ND2 . ASN B 1 149 ? 32.93480 13.23599  47.86210  1.000 16.94014 ? 149 ASN B ND2 1 
ATOM   2188 N N   . LEU B 1 150 ? 37.13877 11.69105  48.66927  1.000 14.59943 ? 150 LEU B N   1 
ATOM   2189 C CA  . LEU B 1 150 ? 38.03275 11.84986  49.80856  1.000 14.69208 ? 150 LEU B CA  1 
ATOM   2190 C C   . LEU B 1 150 ? 37.98255 13.23006  50.45441  1.000 15.81176 ? 150 LEU B C   1 
ATOM   2191 O O   . LEU B 1 150 ? 38.67720 13.44601  51.44799  1.000 18.58295 ? 150 LEU B O   1 
ATOM   2192 C CB  . LEU B 1 150 ? 39.47519 11.53142  49.39404  1.000 15.07318 ? 150 LEU B CB  1 
ATOM   2193 C CG  . LEU B 1 150 ? 39.66164 10.11172  48.86308  1.000 15.24173 ? 150 LEU B CG  1 
ATOM   2194 C CD1 . LEU B 1 150 ? 41.04563 9.95634   48.23449  1.000 14.81525 ? 150 LEU B CD1 1 
ATOM   2195 C CD2 . LEU B 1 150 ? 39.46625 9.09607   49.99860  1.000 16.00139 ? 150 LEU B CD2 1 
ATOM   2196 N N   . ILE B 1 151 ? 37.20352 14.16651  49.92535  1.000 16.50069 ? 151 ILE B N   1 
ATOM   2197 C CA  . ILE B 1 151 ? 37.11559 15.51657  50.49463  1.000 15.52526 ? 151 ILE B CA  1 
ATOM   2198 C C   . ILE B 1 151 ? 35.89393 15.67276  51.38816  1.000 17.97867 ? 151 ILE B C   1 
ATOM   2199 O O   . ILE B 1 151 ? 35.99412 16.19319  52.50172  1.000 19.26946 ? 151 ILE B O   1 
ATOM   2200 C CB  . ILE B 1 151 ? 37.13283 16.58445  49.38175  1.000 15.76962 ? 151 ILE B CB  1 
ATOM   2201 C CG1 . ILE B 1 151 ? 38.48434 16.56954  48.65261  1.000 15.41575 ? 151 ILE B CG1 1 
ATOM   2202 C CG2 . ILE B 1 151 ? 36.89224 17.96723  49.97180  1.000 16.65728 ? 151 ILE B CG2 1 
ATOM   2203 C CD1 . ILE B 1 151 ? 38.52151 17.53224  47.48001  1.000 17.90218 ? 151 ILE B CD1 1 
ATOM   2204 N N   . THR B 1 152 ? 34.73202 15.25476  50.89419  1.000 16.54021 ? 152 THR B N   1 
ATOM   2205 C CA  . THR B 1 152 ? 33.46409 15.35121  51.60483  1.000 16.49334 ? 152 THR B CA  1 
ATOM   2206 C C   . THR B 1 152 ? 32.88668 13.95888  51.81044  1.000 15.86002 ? 152 THR B C   1 
ATOM   2207 O O   . THR B 1 152 ? 33.35861 12.97028  51.24453  1.000 17.38348 ? 152 THR B O   1 
ATOM   2208 C CB  . THR B 1 152 ? 32.43677 16.17686  50.81502  1.000 15.57712 ? 152 THR B CB  1 
ATOM   2209 O OG1 . THR B 1 152 ? 32.00977 15.45492  49.65026  1.000 16.32152 ? 152 THR B OG1 1 
ATOM   2210 C CG2 . THR B 1 152 ? 33.01062 17.53308  50.41007  1.000 17.90756 ? 152 THR B CG2 1 
ATOM   2211 N N   . SER B 1 153 ? 31.81338 13.89812  52.60261  1.000 18.00558 ? 153 SER B N   1 
ATOM   2212 C CA  . SER B 1 153 ? 31.06010 12.67005  52.82201  1.000 17.45809 ? 153 SER B CA  1 
ATOM   2213 C C   . SER B 1 153 ? 30.01519 12.41731  51.74335  1.000 15.48193 ? 153 SER B C   1 
ATOM   2214 O O   . SER B 1 153 ? 29.30350 11.40329  51.80186  1.000 16.28292 ? 153 SER B O   1 
ATOM   2215 C CB  . SER B 1 153 ? 30.36835 12.73070  54.18504  1.000 19.03087 ? 153 SER B CB  1 
ATOM   2216 O OG  . SER B 1 153 ? 29.36130 13.73398  54.18474  1.000 20.56241 ? 153 SER B OG  1 
ATOM   2217 N N   . THR B 1 154 ? 29.91274 13.30043  50.75944  1.000 16.74554 ? 154 THR B N   1 
ATOM   2218 C CA  . THR B 1 154 ? 28.93459 13.14837  49.69758  1.000 15.52265 ? 154 THR B CA  1 
ATOM   2219 C C   . THR B 1 154 ? 29.10334 11.83191  48.95047  1.000 16.82952 ? 154 THR B C   1 
ATOM   2220 O O   . THR B 1 154 ? 30.20341 11.47761  48.51744  1.000 16.91308 ? 154 THR B O   1 
ATOM   2221 C CB  . THR B 1 154 ? 29.07109 14.32834  48.74337  1.000 17.01588 ? 154 THR B CB  1 
ATOM   2222 O OG1 . THR B 1 154 ? 28.78001 15.53200  49.46585  1.000 15.85020 ? 154 THR B OG1 1 
ATOM   2223 C CG2 . THR B 1 154 ? 28.11724 14.19184  47.56820  1.000 16.64550 ? 154 THR B CG2 1 
ATOM   2224 N N   . SER B 1 155 ? 27.99888 11.10783  48.81671  1.000 17.18376 ? 155 SER B N   1 
ATOM   2225 C CA  . SER B 1 155 ? 27.91192 9.91410   47.99445  1.000 16.46899 ? 155 SER B CA  1 
ATOM   2226 C C   . SER B 1 155 ? 27.19332 10.28757  46.71442  1.000 17.00886 ? 155 SER B C   1 
ATOM   2227 O O   . SER B 1 155 ? 26.18190 10.99690  46.74120  1.000 19.40016 ? 155 SER B O   1 
ATOM   2228 C CB  . SER B 1 155 ? 27.10347 8.82890   48.70384  1.000 21.85976 ? 155 SER B CB  1 
ATOM   2229 O OG  . SER B 1 155 ? 27.79669 8.34009   49.83655  1.000 27.38355 ? 155 SER B OG  1 
ATOM   2230 N N   . HIS B 1 156 ? 27.71177 9.81526   45.59111  1.000 17.52395 ? 156 HIS B N   1 
ATOM   2231 C CA  . HIS B 1 156 ? 27.07668 10.05768  44.31072  1.000 16.32877 ? 156 HIS B CA  1 
ATOM   2232 C C   . HIS B 1 156 ? 26.33341 8.80892   43.86756  1.000 18.77752 ? 156 HIS B C   1 
ATOM   2233 O O   . HIS B 1 156 ? 26.94776 7.76966   43.60686  1.000 17.04945 ? 156 HIS B O   1 
ATOM   2234 C CB  . HIS B 1 156 ? 28.08496 10.44091  43.23836  1.000 17.48282 ? 156 HIS B CB  1 
ATOM   2235 C CG  . HIS B 1 156 ? 27.43117 11.00512  42.02759  1.000 19.82209 ? 156 HIS B CG  1 
ATOM   2236 N ND1 . HIS B 1 156 ? 26.98425 10.21955  40.98926  1.000 20.33435 ? 156 HIS B ND1 1 
ATOM   2237 C CD2 . HIS B 1 156 ? 27.09194 12.27626  41.71604  1.000 15.38728 ? 156 HIS B CD2 1 
ATOM   2238 C CE1 . HIS B 1 156 ? 26.40671 10.98727  40.08362  1.000 16.72899 ? 156 HIS B CE1 1 
ATOM   2239 N NE2 . HIS B 1 156 ? 26.46296 12.24015  40.49783  1.000 21.47178 ? 156 HIS B NE2 1 
ATOM   2240 N N   . SER B 1 157 ? 25.02673 8.91496   43.74033  1.000 17.33960 ? 157 SER B N   1 
ATOM   2241 C CA  . SER B 1 157 ? 24.20982 7.77241   43.37048  1.000 17.98258 ? 157 SER B CA  1 
ATOM   2242 C C   . SER B 1 157 ? 23.84180 7.90452   41.89891  1.000 16.61642 ? 157 SER B C   1 
ATOM   2243 O O   . SER B 1 157 ? 23.08660 8.80437   41.51827  1.000 20.55469 ? 157 SER B O   1 
ATOM   2244 C CB  . SER B 1 157 ? 22.97507 7.70087   44.26041  1.000 19.94883 ? 157 SER B CB  1 
ATOM   2245 O OG  . SER B 1 157 ? 22.40084 6.41697   44.17482  1.000 24.70434 ? 157 SER B OG  1 
ATOM   2246 N N   . GLY B 1 158 ? 24.37748 7.01258   41.07223  1.000 16.80946 ? 158 GLY B N   1 
ATOM   2247 C CA  . GLY B 1 158 ? 24.15208 7.05467   39.64224  1.000 18.70581 ? 158 GLY B CA  1 
ATOM   2248 C C   . GLY B 1 158 ? 23.43583 5.81119   39.14966  1.000 18.56875 ? 158 GLY B C   1 
ATOM   2249 O O   . GLY B 1 158 ? 23.58951 4.71903   39.71003  1.000 18.67416 ? 158 GLY B O   1 
ATOM   2250 N N   . SER B 1 159 ? 22.62610 5.99228   38.10888  1.000 20.99843 ? 159 SER B N   1 
ATOM   2251 C CA  . SER B 1 159 ? 21.98221 4.89059   37.40518  1.000 23.18214 ? 159 SER B CA  1 
ATOM   2252 C C   . SER B 1 159 ? 22.15988 5.13674   35.91699  1.000 24.60487 ? 159 SER B C   1 
ATOM   2253 O O   . SER B 1 159 ? 21.65573 6.12967   35.38467  1.000 25.20434 ? 159 SER B O   1 
ATOM   2254 C CB  . SER B 1 159 ? 20.49932 4.80307   37.75779  1.000 26.29901 ? 159 SER B CB  1 
ATOM   2255 O OG  . SER B 1 159 ? 19.89130 3.68850   37.12945  1.000 31.18474 ? 159 SER B OG  1 
ATOM   2256 N N   . VAL B 1 160 ? 22.89657 4.25387   35.25455  1.000 22.52034 ? 160 VAL B N   1 
ATOM   2257 C CA  . VAL B 1 160 ? 23.21196 4.38193   33.84392  1.000 22.52034 ? 160 VAL B CA  1 
ATOM   2258 C C   . VAL B 1 160 ? 22.95204 3.03434   33.17797  1.000 23.93577 ? 160 VAL B C   1 
ATOM   2259 O O   . VAL B 1 160 ? 22.49472 2.09171   33.82391  1.000 26.82754 ? 160 VAL B O   1 
ATOM   2260 C CB  . VAL B 1 160 ? 24.65046 4.88130   33.60871  1.000 22.17728 ? 160 VAL B CB  1 
ATOM   2261 C CG1 . VAL B 1 160 ? 24.81023 6.30890   34.15035  1.000 26.44807 ? 160 VAL B CG1 1 
ATOM   2262 C CG2 . VAL B 1 160 ? 25.64704 3.94093   34.25341  1.000 24.52488 ? 160 VAL B CG2 1 
ATOM   2263 N N   . THR B 1 161 ? 23.19338 2.95964   31.86664  1.000 22.47445 ? 161 THR B N   1 
ATOM   2264 C CA  . THR B 1 161 ? 22.95848 1.72653   31.12634  1.000 23.53804 ? 161 THR B CA  1 
ATOM   2265 C C   . THR B 1 161 ? 24.17636 1.35202   30.29698  1.000 22.07690 ? 161 THR B C   1 
ATOM   2266 O O   . THR B 1 161 ? 24.88717 2.21283   29.76867  1.000 22.82227 ? 161 THR B O   1 
ATOM   2267 C CB  . THR B 1 161 ? 21.69932 1.76460   30.22272  1.000 26.53968 ? 161 THR B CB  1 
ATOM   2268 O OG1 . THR B 1 161 ? 21.83401 2.79496   29.23984  1.000 27.40202 ? 161 THR B OG1 1 
ATOM   2269 C CG2 . THR B 1 161 ? 20.45922 2.02204   31.04932  1.000 28.92439 ? 161 THR B CG2 1 
ATOM   2270 N N   . LEU B 1 162 ? 24.37797 0.04639   30.15558  1.000 19.15944 ? 162 LEU B N   1 
ATOM   2271 C CA  . LEU B 1 162 ? 25.54520 -0.46931  29.46124  1.000 18.92041 ? 162 LEU B CA  1 
ATOM   2272 C C   . LEU B 1 162 ? 25.45894 -0.18856  27.96631  1.000 18.28228 ? 162 LEU B C   1 
ATOM   2273 O O   . LEU B 1 162 ? 24.37741 -0.17761  27.36635  1.000 20.08981 ? 162 LEU B O   1 
ATOM   2274 C CB  . LEU B 1 162 ? 25.69393 -1.97159  29.70873  1.000 20.65637 ? 162 LEU B CB  1 
ATOM   2275 C CG  . LEU B 1 162 ? 26.52780 -2.37038  30.93083  1.000 18.91148 ? 162 LEU B CG  1 
ATOM   2276 C CD1 . LEU B 1 162 ? 25.88537 -1.94041  32.24697  1.000 16.54643 ? 162 LEU B CD1 1 
ATOM   2277 C CD2 . LEU B 1 162 ? 26.80428 -3.87849  30.93750  1.000 19.36826 ? 162 LEU B CD2 1 
ATOM   2278 N N   . VAL B 1 163 ? 26.62842 0.03998   27.37374  1.000 18.02958 ? 163 VAL B N   1 
ATOM   2279 C CA  . VAL B 1 163 ? 26.80132 0.33602   25.95906  1.000 21.10187 ? 163 VAL B CA  1 
ATOM   2280 C C   . VAL B 1 163 ? 27.79615 -0.67834  25.41121  1.000 20.53118 ? 163 VAL B C   1 
ATOM   2281 O O   . VAL B 1 163 ? 28.75806 -1.04158  26.09622  1.000 19.48183 ? 163 VAL B O   1 
ATOM   2282 C CB  . VAL B 1 163 ? 27.36758 1.76609   25.79812  1.000 21.38956 ? 163 VAL B CB  1 
ATOM   2283 C CG1 . VAL B 1 163 ? 27.59591 2.11341   24.32641  1.000 25.04593 ? 163 VAL B CG1 1 
ATOM   2284 C CG2 . VAL B 1 163 ? 26.45797 2.79075   26.46466  1.000 25.00559 ? 163 VAL B CG2 1 
ATOM   2285 N N   . ALA B 1 164 ? 27.57405 -1.14519  24.18679  1.000 21.30047 ? 164 ALA B N   1 
ATOM   2286 C CA  . ALA B 1 164 ? 28.53593 -2.05605  23.58256  1.000 21.58165 ? 164 ALA B CA  1 
ATOM   2287 C C   . ALA B 1 164 ? 29.86379 -1.34456  23.32873  1.000 22.96257 ? 164 ALA B C   1 
ATOM   2288 O O   . ALA B 1 164 ? 29.90430 -0.14232  23.04861  1.000 24.08492 ? 164 ALA B O   1 
ATOM   2289 C CB  . ALA B 1 164 ? 27.98548 -2.61204  22.27166  1.000 24.52652 ? 164 ALA B CB  1 
ATOM   2290 N N   . ALA B 1 165 ? 30.95795 -2.09608  23.45073  1.000 20.40918 ? 165 ALA B N   1 
ATOM   2291 C CA  . ALA B 1 165 ? 32.27661 -1.52082  23.21019  1.000 23.50391 ? 165 ALA B CA  1 
ATOM   2292 C C   . ALA B 1 165 ? 32.35221 -0.97989  21.78329  1.000 26.63051 ? 165 ALA B C   1 
ATOM   2293 O O   . ALA B 1 165 ? 31.79151 -1.58544  20.86169  1.000 24.51920 ? 165 ALA B O   1 
ATOM   2294 C CB  . ALA B 1 165 ? 33.36978 -2.57405  23.42358  1.000 20.12397 ? 165 ALA B CB  1 
ATOM   2295 N N   . PRO B 1 166 ? 33.03287 0.16047   21.56062  1.000 25.98423 ? 166 PRO B N   1 
ATOM   2296 C CA  . PRO B 1 166 ? 33.13454 0.82461   20.25268  1.000 27.98338 ? 166 PRO B CA  1 
ATOM   2297 C C   . PRO B 1 166 ? 33.73320 -0.08952  19.18009  1.000 30.94615 ? 166 PRO B C   1 
ATOM   2298 O O   . PRO B 1 166 ? 34.66319 -0.85329  19.45134  1.000 33.40004 ? 166 PRO B O   1 
ATOM   2299 C CB  . PRO B 1 166 ? 34.10574 1.98614   20.50282  1.000 29.19330 ? 166 PRO B CB  1 
ATOM   2300 C CG  . PRO B 1 166 ? 34.29315 2.09267   21.95575  1.000 26.03096 ? 166 PRO B CG  1 
ATOM   2301 C CD  . PRO B 1 166 ? 33.67283 0.92367   22.64188  1.000 21.96869 ? 166 PRO B CD  1 
ATOM   2302 O OXT . PRO B 1 166 ? 33.32267 -0.07348  18.01624  1.000 37.60859 ? 166 PRO B OXT 1 
ATOM   2303 N N   . GLU C 1 5   ? 47.11593 26.65296  -15.98275 1.000 22.55912 ? 5   GLU C N   1 
ATOM   2304 C CA  . GLU C 1 5   ? 48.30709 26.07113  -15.36044 1.000 19.04956 ? 5   GLU C CA  1 
ATOM   2305 C C   . GLU C 1 5   ? 47.93401 25.16921  -14.18573 1.000 20.20133 ? 5   GLU C C   1 
ATOM   2306 O O   . GLU C 1 5   ? 47.11975 25.55098  -13.34978 1.000 19.61673 ? 5   GLU C O   1 
ATOM   2307 C CB  . GLU C 1 5   ? 49.23618 27.16918  -14.82795 1.000 21.67720 ? 5   GLU C CB  1 
ATOM   2308 C CG  . GLU C 1 5   ? 49.93204 28.02012  -15.88209 1.000 20.57426 ? 5   GLU C CG  1 
ATOM   2309 C CD  . GLU C 1 5   ? 50.95407 27.23716  -16.69700 1.000 22.36259 ? 5   GLU C CD  1 
ATOM   2310 O OE1 . GLU C 1 5   ? 51.42827 27.76037  -17.73118 1.000 25.77476 ? 5   GLU C OE1 1 
ATOM   2311 O OE2 . GLU C 1 5   ? 51.27589 26.10044  -16.31184 1.000 21.84145 ? 5   GLU C OE2 1 
ATOM   2312 N N   . ALA C 1 6   ? 48.55117 23.99282  -14.09463 1.000 19.14472 ? 6   ALA C N   1 
ATOM   2313 C CA  . ALA C 1 6   ? 48.38452 23.15494  -12.91493 1.000 18.46795 ? 6   ALA C CA  1 
ATOM   2314 C C   . ALA C 1 6   ? 49.29928 23.66164  -11.80861 1.000 18.94276 ? 6   ALA C C   1 
ATOM   2315 O O   . ALA C 1 6   ? 50.49865 23.84954  -12.03075 1.000 18.50414 ? 6   ALA C O   1 
ATOM   2316 C CB  . ALA C 1 6   ? 48.72671 21.70176  -13.23644 1.000 17.18434 ? 6   ALA C CB  1 
ATOM   2317 N N   . SER C 1 7   ? 48.73612 23.87864  -10.61744 1.000 15.79274 ? 7   SER C N   1 
ATOM   2318 C CA  . SER C 1 7   ? 49.46419 24.52231  -9.52883  1.000 15.52344 ? 7   SER C CA  1 
ATOM   2319 C C   . SER C 1 7   ? 49.47428 23.65340  -8.26932  1.000 15.63095 ? 7   SER C C   1 
ATOM   2320 O O   . SER C 1 7   ? 49.59375 22.43025  -8.36325  1.000 14.80617 ? 7   SER C O   1 
ATOM   2321 C CB  . SER C 1 7   ? 48.89228 25.92154  -9.27571  1.000 15.52748 ? 7   SER C CB  1 
ATOM   2322 O OG  . SER C 1 7   ? 49.75043 26.68465  -8.44326  1.000 15.30778 ? 7   SER C OG  1 
ATOM   2323 N N   . LYS C 1 8   ? 49.33459 24.26696  -7.09559  1.000 15.13558 ? 8   LYS C N   1 
ATOM   2324 C CA  . LYS C 1 8   ? 49.59472 23.57206  -5.83418  1.000 15.33163 ? 8   LYS C CA  1 
ATOM   2325 C C   . LYS C 1 8   ? 48.68775 22.35789  -5.63708  1.000 13.00335 ? 8   LYS C C   1 
ATOM   2326 O O   . LYS C 1 8   ? 47.47997 22.40595  -5.89513  1.000 14.24347 ? 8   LYS C O   1 
ATOM   2327 C CB  . LYS C 1 8   ? 49.43145 24.55604  -4.67065  1.000 16.38666 ? 8   LYS C CB  1 
ATOM   2328 C CG  . LYS C 1 8   ? 50.51153 25.63724  -4.67828  1.000 19.77914 ? 8   LYS C CG  1 
ATOM   2329 C CD  . LYS C 1 8   ? 50.40292 26.58833  -3.50752  1.000 21.67709 ? 8   LYS C CD  1 
ATOM   2330 C CE  . LYS C 1 8   ? 51.57597 27.57366  -3.50352  1.000 22.06006 ? 8   LYS C CE  1 
ATOM   2331 N NZ  . LYS C 1 8   ? 51.61446 28.45579  -4.70661  1.000 25.03013 ? 8   LYS C NZ  1 
ATOM   2332 N N   . GLY C 1 9   ? 49.28860 21.26435  -5.15842  1.000 13.23739 ? 9   GLY C N   1 
ATOM   2333 C CA  . GLY C 1 9   ? 48.60934 20.00200  -4.98060  1.000 13.53467 ? 9   GLY C CA  1 
ATOM   2334 C C   . GLY C 1 9   ? 48.71333 19.08162  -6.17054  1.000 12.79394 ? 9   GLY C C   1 
ATOM   2335 O O   . GLY C 1 9   ? 48.50958 17.86939  -6.02470  1.000 13.99999 ? 9   GLY C O   1 
ATOM   2336 N N   . LEU C 1 10  ? 49.03748 19.62928  -7.33438  1.000 12.68390 ? 10  LEU C N   1 
ATOM   2337 C CA  . LEU C 1 10  ? 49.11613 18.88421  -8.57749  1.000 12.79781 ? 10  LEU C CA  1 
ATOM   2338 C C   . LEU C 1 10  ? 50.55491 18.82256  -9.06887  1.000 15.65662 ? 10  LEU C C   1 
ATOM   2339 O O   . LEU C 1 10  ? 51.41646 19.62231  -8.68432  1.000 15.00593 ? 10  LEU C O   1 
ATOM   2340 C CB  . LEU C 1 10  ? 48.23990 19.55362  -9.63756  1.000 13.80098 ? 10  LEU C CB  1 
ATOM   2341 C CG  . LEU C 1 10  ? 46.76119 19.70236  -9.27675  1.000 12.87820 ? 10  LEU C CG  1 
ATOM   2342 C CD1 . LEU C 1 10  ? 46.04788 20.40695  -10.42694 1.000 13.80541 ? 10  LEU C CD1 1 
ATOM   2343 C CD2 . LEU C 1 10  ? 46.12558 18.35270  -8.97224  1.000 13.63947 ? 10  LEU C CD2 1 
ATOM   2344 N N   . GLN C 1 11  ? 50.80887 17.83277  -9.91711  1.000 16.00479 ? 11  GLN C N   1 
ATOM   2345 C CA  . GLN C 1 11  ? 52.09558 17.72062  -10.57962 1.000 17.40058 ? 11  GLN C CA  1 
ATOM   2346 C C   . GLN C 1 11  ? 51.87583 17.27967  -12.01468 1.000 18.19413 ? 11  GLN C C   1 
ATOM   2347 O O   . GLN C 1 11  ? 50.84335 16.69342  -12.36019 1.000 18.87505 ? 11  GLN C O   1 
ATOM   2348 C CB  . GLN C 1 11  ? 53.05189 16.78560  -9.83635  1.000 17.93193 ? 11  GLN C CB  1 
ATOM   2349 C CG  . GLN C 1 11  ? 52.60038 15.36915  -9.74544  1.000 20.13820 ? 11  GLN C CG  1 
ATOM   2350 C CD  . GLN C 1 11  ? 53.55290 14.53704  -8.92204  1.000 25.16604 ? 11  GLN C CD  1 
ATOM   2351 O OE1 . GLN C 1 11  ? 54.68441 14.95340  -8.65723  1.000 27.08718 ? 11  GLN C OE1 1 
ATOM   2352 N NE2 . GLN C 1 11  ? 53.10232 13.35797  -8.50253  1.000 28.41620 ? 11  GLN C NE2 1 
ATOM   2353 N N   . VAL C 1 12  ? 52.86192 17.57920  -12.85289 1.000 17.95354 ? 12  VAL C N   1 
ATOM   2354 C CA  . VAL C 1 12  ? 52.74923 17.37846  -14.28870 1.000 18.08252 ? 12  VAL C CA  1 
ATOM   2355 C C   . VAL C 1 12  ? 53.91117 16.51308  -14.74111 1.000 16.24609 ? 12  VAL C C   1 
ATOM   2356 O O   . VAL C 1 12  ? 55.06250 16.76219  -14.36683 1.000 17.61662 ? 12  VAL C O   1 
ATOM   2357 C CB  . VAL C 1 12  ? 52.73980 18.71829  -15.04250 1.000 18.04731 ? 12  VAL C CB  1 
ATOM   2358 C CG1 . VAL C 1 12  ? 52.48615 18.49123  -16.52366 1.000 20.63007 ? 12  VAL C CG1 1 
ATOM   2359 C CG2 . VAL C 1 12  ? 51.68845 19.66825  -14.45176 1.000 17.96183 ? 12  VAL C CG2 1 
ATOM   2360 N N   . THR C 1 13  ? 53.60198 15.48207  -15.51523 1.000 16.89662 ? 13  THR C N   1 
ATOM   2361 C CA  . THR C 1 13  ? 54.59874 14.68344  -16.21296 1.000 17.46599 ? 13  THR C CA  1 
ATOM   2362 C C   . THR C 1 13  ? 54.21786 14.62954  -17.68424 1.000 18.09892 ? 13  THR C C   1 
ATOM   2363 O O   . THR C 1 13  ? 53.19336 15.18122  -18.10922 1.000 18.25778 ? 13  THR C O   1 
ATOM   2364 C CB  . THR C 1 13  ? 54.66888 13.24948  -15.66777 1.000 20.42393 ? 13  THR C CB  1 
ATOM   2365 O OG1 . THR C 1 13  ? 53.50114 12.52943  -16.08179 1.000 22.72111 ? 13  THR C OG1 1 
ATOM   2366 C CG2 . THR C 1 13  ? 54.77287 13.24116  -14.14608 1.000 21.51171 ? 13  THR C CG2 1 
ATOM   2367 N N   . ALA C 1 14  ? 55.04477 13.92452  -18.46752 1.000 18.37883 ? 14  ALA C N   1 
ATOM   2368 C CA  . ALA C 1 14  ? 54.71994 13.72523  -19.87488 1.000 20.67276 ? 14  ALA C CA  1 
ATOM   2369 C C   . ALA C 1 14  ? 53.40319 12.98761  -20.05568 1.000 20.25787 ? 14  ALA C C   1 
ATOM   2370 O O   . ALA C 1 14  ? 52.81275 13.05207  -21.13819 1.000 21.28287 ? 14  ALA C O   1 
ATOM   2371 C CB  . ALA C 1 14  ? 55.85425 12.97996  -20.58461 1.000 19.99444 ? 14  ALA C CB  1 
ATOM   2372 N N   . SER C 1 15  ? 52.92763 12.29777  -19.02153 1.000 20.61623 ? 15  SER C N   1 
ATOM   2373 C CA  . SER C 1 15  ? 51.66615 11.57107  -19.07761 1.000 20.18310 ? 15  SER C CA  1 
ATOM   2374 C C   . SER C 1 15  ? 50.45936 12.40550  -18.65399 1.000 24.40177 ? 15  SER C C   1 
ATOM   2375 O O   . SER C 1 15  ? 49.32688 11.93335  -18.79037 1.000 26.34323 ? 15  SER C O   1 
ATOM   2376 C CB  . SER C 1 15  ? 51.75531 10.32232  -18.19932 1.000 26.07043 ? 15  SER C CB  1 
ATOM   2377 O OG  . SER C 1 15  ? 52.71130 9.41536   -18.71838 1.000 24.84726 ? 15  SER C OG  1 
ATOM   2378 N N   . GLY C 1 16  ? 50.65817 13.61922  -18.13687 1.000 18.92829 ? 16  GLY C N   1 
ATOM   2379 C CA  . GLY C 1 16  ? 49.52993 14.46279  -17.81500 1.000 20.28545 ? 16  GLY C CA  1 
ATOM   2380 C C   . GLY C 1 16  ? 49.62871 14.98995  -16.40179 1.000 19.19097 ? 16  GLY C C   1 
ATOM   2381 O O   . GLY C 1 16  ? 50.70059 14.97800  -15.78781 1.000 18.44994 ? 16  GLY C O   1 
ATOM   2382 N N   . VAL C 1 17  ? 48.49174 15.46238  -15.89281 1.000 18.49111 ? 17  VAL C N   1 
ATOM   2383 C CA  . VAL C 1 17  ? 48.41035 16.10858  -14.58565 1.000 18.79142 ? 17  VAL C CA  1 
ATOM   2384 C C   . VAL C 1 17  ? 47.89556 15.10302  -13.57061 1.000 19.47618 ? 17  VAL C C   1 
ATOM   2385 O O   . VAL C 1 17  ? 46.92400 14.38520  -13.82979 1.000 19.70034 ? 17  VAL C O   1 
ATOM   2386 C CB  . VAL C 1 17  ? 47.49779 17.34036  -14.64244 1.000 17.45883 ? 17  VAL C CB  1 
ATOM   2387 C CG1 . VAL C 1 17  ? 47.46834 18.03839  -13.28514 1.000 17.37442 ? 17  VAL C CG1 1 
ATOM   2388 C CG2 . VAL C 1 17  ? 47.98990 18.27885  -15.71935 1.000 18.44802 ? 17  VAL C CG2 1 
ATOM   2389 N N   . SER C 1 18  ? 48.53918 15.05675  -12.40925 1.000 16.51311 ? 18  SER C N   1 
ATOM   2390 C CA  . SER C 1 18  ? 48.14864 14.14671  -11.34926 1.000 18.51758 ? 18  SER C CA  1 
ATOM   2391 C C   . SER C 1 18  ? 48.15640 14.90940  -10.03366 1.000 16.39979 ? 18  SER C C   1 
ATOM   2392 O O   . SER C 1 18  ? 48.62527 16.05028  -9.95212  1.000 15.20862 ? 18  SER C O   1 
ATOM   2393 C CB  . SER C 1 18  ? 49.08652 12.92813  -11.29399 1.000 19.46248 ? 18  SER C CB  1 
ATOM   2394 O OG  . SER C 1 18  ? 50.42953 13.34189  -11.09737 1.000 22.45993 ? 18  SER C OG  1 
ATOM   2395 N N   . VAL C 1 19  ? 47.61027 14.27720  -9.00416  1.000 14.41371 ? 19  VAL C N   1 
ATOM   2396 C CA  . VAL C 1 19  ? 47.73780 14.79100  -7.64214  1.000 14.78791 ? 19  VAL C CA  1 
ATOM   2397 C C   . VAL C 1 19  ? 49.09314 14.36673  -7.10259  1.000 15.76718 ? 19  VAL C C   1 
ATOM   2398 O O   . VAL C 1 19  ? 49.47936 13.19385  -7.21413  1.000 18.47382 ? 19  VAL C O   1 
ATOM   2399 C CB  . VAL C 1 19  ? 46.60884 14.25337  -6.74738  1.000 14.50503 ? 19  VAL C CB  1 
ATOM   2400 C CG1 . VAL C 1 19  ? 46.79325 14.72947  -5.30665  1.000 16.48486 ? 19  VAL C CG1 1 
ATOM   2401 C CG2 . VAL C 1 19  ? 45.24789 14.67765  -7.27684  1.000 16.53846 ? 19  VAL C CG2 1 
ATOM   2402 N N   . GLN C 1 20  ? 49.81998 15.31251  -6.51323  1.000 14.18581 ? 20  GLN C N   1 
ATOM   2403 C CA  . GLN C 1 20  ? 51.09643 15.01100  -5.88570  1.000 14.03384 ? 20  GLN C CA  1 
ATOM   2404 C C   . GLN C 1 20  ? 50.87034 14.60862  -4.43280  1.000 14.23523 ? 20  GLN C C   1 
ATOM   2405 O O   . GLN C 1 20  ? 50.23336 15.34237  -3.67040  1.000 15.01587 ? 20  GLN C O   1 
ATOM   2406 C CB  . GLN C 1 20  ? 52.03713 16.20971  -5.94975  1.000 14.40962 ? 20  GLN C CB  1 
ATOM   2407 C CG  . GLN C 1 20  ? 53.38586 15.86630  -5.34074  1.000 16.25694 ? 20  GLN C CG  1 
ATOM   2408 C CD  . GLN C 1 20  ? 54.44012 16.90150  -5.60105  1.000 21.06298 ? 20  GLN C CD  1 
ATOM   2409 O OE1 . GLN C 1 20  ? 54.15349 18.00232  -6.07301  1.000 24.23989 ? 20  GLN C OE1 1 
ATOM   2410 N NE2 . GLN C 1 20  ? 55.68204 16.54865  -5.30776  1.000 22.47228 ? 20  GLN C NE2 1 
ATOM   2411 N N   . ALA C 1 21  ? 51.41323 13.45330  -4.05352  1.000 15.15097 ? 21  ALA C N   1 
ATOM   2412 C CA  . ALA C 1 21  ? 51.23879 12.94122  -2.70247  1.000 16.84770 ? 21  ALA C CA  1 
ATOM   2413 C C   . ALA C 1 21  ? 52.26885 13.56911  -1.77539  1.000 17.69872 ? 21  ALA C C   1 
ATOM   2414 O O   . ALA C 1 21  ? 53.47722 13.38852  -1.97139  1.000 20.19094 ? 21  ALA C O   1 
ATOM   2415 C CB  . ALA C 1 21  ? 51.37918 11.42234  -2.69917  1.000 18.03650 ? 21  ALA C CB  1 
ATOM   2416 N N   . GLY C 1 22  ? 51.79416 14.30527  -0.77228  1.000 15.77500 ? 22  GLY C N   1 
ATOM   2417 C CA  . GLY C 1 22  ? 52.61888 14.76054  0.33031   1.000 13.77900 ? 22  GLY C CA  1 
ATOM   2418 C C   . GLY C 1 22  ? 52.46911 13.86644  1.54757   1.000 15.01405 ? 22  GLY C C   1 
ATOM   2419 O O   . GLY C 1 22  ? 51.93385 12.75437  1.47625   1.000 14.51130 ? 22  GLY C O   1 
ATOM   2420 N N   . ASP C 1 23  ? 52.95029 14.35595  2.69459   1.000 14.85683 ? 23  ASP C N   1 
ATOM   2421 C CA  . ASP C 1 23  ? 52.98499 13.49582  3.87434   1.000 15.91842 ? 23  ASP C CA  1 
ATOM   2422 C C   . ASP C 1 23  ? 51.58021 13.05951  4.27991   1.000 14.93395 ? 23  ASP C C   1 
ATOM   2423 O O   . ASP C 1 23  ? 50.65975 13.88315  4.36076   1.000 14.25329 ? 23  ASP C O   1 
ATOM   2424 C CB  . ASP C 1 23  ? 53.62960 14.21822  5.05516   1.000 16.86786 ? 23  ASP C CB  1 
ATOM   2425 C CG  . ASP C 1 23  ? 55.12296 14.40687  4.89462   1.000 22.86236 ? 23  ASP C CG  1 
ATOM   2426 O OD1 . ASP C 1 23  ? 55.73935 13.76928  4.01904   1.000 18.04627 ? 23  ASP C OD1 1 
ATOM   2427 O OD2 . ASP C 1 23  ? 55.67307 15.17878  5.69582   1.000 23.40391 ? 23  ASP C OD2 1 
ATOM   2428 N N   . GLY C 1 24  ? 51.43548 11.76740  4.58358   1.000 14.16343 ? 24  GLY C N   1 
ATOM   2429 C CA  . GLY C 1 24  ? 50.17052 11.20686  5.00457   1.000 14.36505 ? 24  GLY C CA  1 
ATOM   2430 C C   . GLY C 1 24  ? 49.20950 10.86924  3.88834   1.000 13.71502 ? 24  GLY C C   1 
ATOM   2431 O O   . GLY C 1 24  ? 48.07123 10.49317  4.17949   1.000 15.71670 ? 24  GLY C O   1 
ATOM   2432 N N   . ILE C 1 25  ? 49.63929 10.97637  2.62905   1.000 15.23725 ? 25  ILE C N   1 
ATOM   2433 C CA  . ILE C 1 25  ? 48.77484 10.79584  1.46550   1.000 13.98507 ? 25  ILE C CA  1 
ATOM   2434 C C   . ILE C 1 25  ? 49.43844 9.83604   0.48326   1.000 14.74384 ? 25  ILE C C   1 
ATOM   2435 O O   . ILE C 1 25  ? 50.66149 9.87197   0.28819   1.000 15.60645 ? 25  ILE C O   1 
ATOM   2436 C CB  . ILE C 1 25  ? 48.48418 12.15955  0.79071   1.000 14.87843 ? 25  ILE C CB  1 
ATOM   2437 C CG1 . ILE C 1 25  ? 47.59105 13.03738  1.67929   1.000 13.23445 ? 25  ILE C CG1 1 
ATOM   2438 C CG2 . ILE C 1 25  ? 47.84210 11.98492  -0.60612  1.000 14.02030 ? 25  ILE C CG2 1 
ATOM   2439 C CD1 . ILE C 1 25  ? 46.14494 12.56699  1.77912   1.000 13.79760 ? 25  ILE C CD1 1 
ATOM   2440 N N   . SER C 1 26  ? 48.62892 8.97398   -0.13347  1.000 16.05122 ? 26  SER C N   1 
ATOM   2441 C CA  . SER C 1 26  ? 49.06109 8.12461   -1.23551  1.000 16.62377 ? 26  SER C CA  1 
ATOM   2442 C C   . SER C 1 26  ? 48.17659 8.41031   -2.43989  1.000 16.86411 ? 26  SER C C   1 
ATOM   2443 O O   . SER C 1 26  ? 46.97033 8.63545   -2.28558  1.000 20.19826 ? 26  SER C O   1 
ATOM   2444 C CB  . SER C 1 26  ? 48.90639 6.65406   -0.85727  1.000 20.94649 ? 26  SER C CB  1 
ATOM   2445 O OG  . SER C 1 26  ? 49.94910 6.25346   0.00493   1.000 30.19174 ? 26  SER C OG  1 
ATOM   2446 N N   . VAL C 1 27  ? 48.76183 8.39421   -3.63577  1.000 18.27904 ? 27  VAL C N   1 
ATOM   2447 C CA  . VAL C 1 27  ? 48.02539 8.65512   -4.87242  1.000 18.69935 ? 27  VAL C CA  1 
ATOM   2448 C C   . VAL C 1 27  ? 48.27001 7.50439   -5.83532  1.000 24.74816 ? 27  VAL C C   1 
ATOM   2449 O O   . VAL C 1 27  ? 49.42027 7.13966   -6.10033  1.000 24.35332 ? 27  VAL C O   1 
ATOM   2450 C CB  . VAL C 1 27  ? 48.42011 9.99134   -5.53259  1.000 19.59808 ? 27  VAL C CB  1 
ATOM   2451 C CG1 . VAL C 1 27  ? 47.72820 10.15079  -6.89008  1.000 21.42587 ? 27  VAL C CG1 1 
ATOM   2452 C CG2 . VAL C 1 27  ? 48.09815 11.17142  -4.61819  1.000 19.33753 ? 27  VAL C CG2 1 
ATOM   2453 N N   . ALA C 1 28  ? 47.18766 6.94479   -6.35994  1.000 24.56992 ? 28  ALA C N   1 
ATOM   2454 C CA  . ALA C 1 28  ? 47.23979 5.88882   -7.35419  1.000 25.50305 ? 28  ALA C CA  1 
ATOM   2455 C C   . ALA C 1 28  ? 46.18185 6.19681   -8.40510  1.000 28.86093 ? 28  ALA C C   1 
ATOM   2456 O O   . ALA C 1 28  ? 45.43012 7.17042   -8.28487  1.000 25.47871 ? 28  ALA C O   1 
ATOM   2457 C CB  . ALA C 1 28  ? 47.01414 4.52718   -6.69036  1.000 25.06312 ? 28  ALA C CB  1 
ATOM   2458 N N   . GLY C 1 29  ? 46.11288 5.35477   -9.44107  1.000 27.12005 ? 29  GLY C N   1 
ATOM   2459 C CA  . GLY C 1 29  ? 45.04242 5.47049   -10.41804 1.000 29.37376 ? 29  GLY C CA  1 
ATOM   2460 C C   . GLY C 1 29  ? 43.65465 5.33274   -9.82353  1.000 27.55205 ? 29  GLY C C   1 
ATOM   2461 O O   . GLY C 1 29  ? 42.67738 5.76255   -10.44653 1.000 30.71752 ? 29  GLY C O   1 
ATOM   2462 N N   . THR C 1 30  ? 43.54695 4.75449   -8.62713  1.000 24.48582 ? 30  THR C N   1 
ATOM   2463 C CA  . THR C 1 30  ? 42.28399 4.60009   -7.91882  1.000 26.28417 ? 30  THR C CA  1 
ATOM   2464 C C   . THR C 1 30  ? 41.93496 5.79170   -7.02945  1.000 27.92853 ? 30  THR C C   1 
ATOM   2465 O O   . THR C 1 30  ? 40.86321 5.78606   -6.41677  1.000 28.53438 ? 30  THR C O   1 
ATOM   2466 C CB  . THR C 1 30  ? 42.33013 3.35089   -7.04885  1.000 24.33205 ? 30  THR C CB  1 
ATOM   2467 O OG1 . THR C 1 30  ? 43.45282 3.44405   -6.16608  1.000 28.07593 ? 30  THR C OG1 1 
ATOM   2468 C CG2 . THR C 1 30  ? 42.46348 2.10141   -7.91872  1.000 30.70100 ? 30  THR C CG2 1 
ATOM   2469 N N   . GLY C 1 31  ? 42.81191 6.77950   -6.90514  1.000 25.84440 ? 31  GLY C N   1 
ATOM   2470 C CA  . GLY C 1 31  ? 42.46729 8.03546   -6.26289  1.000 20.88873 ? 31  GLY C CA  1 
ATOM   2471 C C   . GLY C 1 31  ? 43.38302 8.38558   -5.10586  1.000 20.70049 ? 31  GLY C C   1 
ATOM   2472 O O   . GLY C 1 31  ? 44.42081 7.75721   -4.87184  1.000 19.94670 ? 31  GLY C O   1 
ATOM   2473 N N   . VAL C 1 32  ? 42.97316 9.42263   -4.36999  1.000 16.65887 ? 32  VAL C N   1 
ATOM   2474 C CA  . VAL C 1 32  ? 43.75939 9.99491   -3.27795  1.000 15.53032 ? 32  VAL C CA  1 
ATOM   2475 C C   . VAL C 1 32  ? 43.34008 9.32523   -1.98097  1.000 14.22651 ? 32  VAL C C   1 
ATOM   2476 O O   . VAL C 1 32  ? 42.15380 9.32708   -1.63560  1.000 16.22872 ? 32  VAL C O   1 
ATOM   2477 C CB  . VAL C 1 32  ? 43.51818 11.51318  -3.18808  1.000 13.31663 ? 32  VAL C CB  1 
ATOM   2478 C CG1 . VAL C 1 32  ? 44.36752 12.11865  -2.06313  1.000 16.05129 ? 32  VAL C CG1 1 
ATOM   2479 C CG2 . VAL C 1 32  ? 43.83554 12.18471  -4.51323  1.000 14.31209 ? 32  VAL C CG2 1 
ATOM   2480 N N   . ALA C 1 33  ? 44.31010 8.77959   -1.23980  1.000 14.16163 ? 33  ALA C N   1 
ATOM   2481 C CA  . ALA C 1 33  ? 44.02049 8.04768   -0.01357  1.000 14.47082 ? 33  ALA C CA  1 
ATOM   2482 C C   . ALA C 1 33  ? 44.93981 8.50984   1.11639   1.000 13.75781 ? 33  ALA C C   1 
ATOM   2483 O O   . ALA C 1 33  ? 46.00656 9.08454   0.88145   1.000 15.21572 ? 33  ALA C O   1 
ATOM   2484 C CB  . ALA C 1 33  ? 44.21108 6.53854   -0.23864  1.000 17.62112 ? 33  ALA C CB  1 
ATOM   2485 N N   . VAL C 1 34  ? 44.50384 8.26857   2.35652   1.000 14.47987 ? 34  VAL C N   1 
ATOM   2486 C CA  . VAL C 1 34  ? 45.35465 8.52660   3.52136   1.000 13.92162 ? 34  VAL C CA  1 
ATOM   2487 C C   . VAL C 1 34  ? 46.32806 7.36933   3.69779   1.000 16.26664 ? 34  VAL C C   1 
ATOM   2488 O O   . VAL C 1 34  ? 45.96335 6.19547   3.54487   1.000 18.09839 ? 34  VAL C O   1 
ATOM   2489 C CB  . VAL C 1 34  ? 44.50170 8.73865   4.78395   1.000 14.60510 ? 34  VAL C CB  1 
ATOM   2490 C CG1 . VAL C 1 34  ? 45.35259 8.76128   6.05399   1.000 15.86873 ? 34  VAL C CG1 1 
ATOM   2491 C CG2 . VAL C 1 34  ? 43.67106 10.02379  4.66750   1.000 14.95952 ? 34  VAL C CG2 1 
ATOM   2492 N N   . LYS C 1 35  ? 47.57240 7.70615   4.02335   1.000 15.17043 ? 35  LYS C N   1 
ATOM   2493 C CA  . LYS C 1 35  ? 48.62034 6.74288   4.34402   1.000 17.22422 ? 35  LYS C CA  1 
ATOM   2494 C C   . LYS C 1 35  ? 48.86485 6.78775   5.84892   1.000 15.88006 ? 35  LYS C C   1 
ATOM   2495 O O   . LYS C 1 35  ? 49.16861 7.85271   6.39254   1.000 16.88811 ? 35  LYS C O   1 
ATOM   2496 C CB  . LYS C 1 35  ? 49.91106 7.11679   3.60871   1.000 16.55562 ? 35  LYS C CB  1 
ATOM   2497 C CG  . LYS C 1 35  ? 51.02865 6.10010   3.82975   1.000 21.69374 ? 35  LYS C CG  1 
ATOM   2498 C CD  . LYS C 1 35  ? 52.37193 6.44939   3.17818   1.000 26.33605 ? 35  LYS C CD  1 
ATOM   2499 C CE  . LYS C 1 35  ? 52.24179 7.15042   1.84429   1.000 27.67749 ? 35  LYS C CE  1 
ATOM   2500 N NZ  . LYS C 1 35  ? 53.58489 7.46184   1.25822   1.000 34.39293 ? 35  LYS C NZ  1 
ATOM   2501 N N   . VAL C 1 36  ? 48.76432 5.63864   6.51205   1.000 15.63241 ? 36  VAL C N   1 
ATOM   2502 C CA  . VAL C 1 36  ? 49.03466 5.54864   7.94495   1.000 18.93776 ? 36  VAL C CA  1 
ATOM   2503 C C   . VAL C 1 36  ? 50.34612 4.80527   8.16063   1.000 19.23999 ? 36  VAL C C   1 
ATOM   2504 O O   . VAL C 1 36  ? 50.70439 3.89354   7.40548   1.000 19.67738 ? 36  VAL C O   1 
ATOM   2505 C CB  . VAL C 1 36  ? 47.89023 4.90371   8.75893   1.000 17.02012 ? 36  VAL C CB  1 
ATOM   2506 C CG1 . VAL C 1 36  ? 46.60519 5.71141   8.59767   1.000 18.50401 ? 36  VAL C CG1 1 
ATOM   2507 C CG2 . VAL C 1 36  ? 47.67266 3.45550   8.34094   1.000 17.85814 ? 36  VAL C CG2 1 
ATOM   2508 N N   . GLU C 1 37  ? 51.06904 5.20709   9.19973   1.000 16.71042 ? 37  GLU C N   1 
ATOM   2509 C CA  . GLU C 1 37  ? 52.33815 4.56707   9.50992   1.000 18.40865 ? 37  GLU C CA  1 
ATOM   2510 C C   . GLU C 1 37  ? 52.08707 3.31639   10.33680  1.000 20.31706 ? 37  GLU C C   1 
ATOM   2511 O O   . GLU C 1 37  ? 51.31360 3.33719   11.29677  1.000 21.37285 ? 37  GLU C O   1 
ATOM   2512 C CB  . GLU C 1 37  ? 53.25661 5.51957   10.27034  1.000 19.23379 ? 37  GLU C CB  1 
ATOM   2513 C CG  . GLU C 1 37  ? 54.57726 4.85320   10.65542  1.000 20.01577 ? 37  GLU C CG  1 
ATOM   2514 C CD  . GLU C 1 37  ? 55.64356 5.81483   11.13599  1.000 20.51748 ? 37  GLU C CD  1 
ATOM   2515 O OE1 . GLU C 1 37  ? 55.35713 7.00986   11.31933  1.000 19.89980 ? 37  GLU C OE1 1 
ATOM   2516 O OE2 . GLU C 1 37  ? 56.79770 5.36260   11.32561  1.000 24.52266 ? 37  GLU C OE2 1 
ATOM   2517 N N   . ALA C 1 38  ? 52.77800 2.23354   9.96226   1.000 23.56476 ? 38  ALA C N   1 
ATOM   2518 C CA  . ALA C 1 38  ? 52.42660 0.88032   10.39309  1.000 27.66715 ? 38  ALA C CA  1 
ATOM   2519 C C   . ALA C 1 38  ? 52.17932 0.77289   11.89749  1.000 27.75753 ? 38  ALA C C   1 
ATOM   2520 O O   . ALA C 1 38  ? 51.07237 0.43374   12.33763  1.000 34.77004 ? 38  ALA C O   1 
ATOM   2521 C CB  . ALA C 1 38  ? 53.53196 -0.08584  9.95989   1.000 28.78166 ? 38  ALA C CB  1 
ATOM   2522 N N   . SER C 1 39  ? 53.20045 1.05295   12.70136  1.000 27.66616 ? 39  SER C N   1 
ATOM   2523 C CA  . SER C 1 39  ? 53.19481 0.71516   14.12051  1.000 24.22645 ? 39  SER C CA  1 
ATOM   2524 C C   . SER C 1 39  ? 52.63722 1.82426   15.00736  1.000 22.91752 ? 39  SER C C   1 
ATOM   2525 O O   . SER C 1 39  ? 52.86218 1.80420   16.22686  1.000 21.42966 ? 39  SER C O   1 
ATOM   2526 C CB  . SER C 1 39  ? 54.61574 0.39239   14.57508  1.000 26.39087 ? 39  SER C CB  1 
ATOM   2527 O OG  . SER C 1 39  ? 55.46533 1.49219   14.30652  1.000 35.60579 ? 39  SER C OG  1 
ATOM   2528 N N   . LYS C 1 40  ? 51.91421 2.78696   14.43747  1.000 17.79375 ? 40  LYS C N   1 
ATOM   2529 C CA  . LYS C 1 40  ? 51.55256 3.99493   15.16547  1.000 19.96512 ? 40  LYS C CA  1 
ATOM   2530 C C   . LYS C 1 40  ? 50.06815 4.07631   15.49295  1.000 17.36010 ? 40  LYS C C   1 
ATOM   2531 O O   . LYS C 1 40  ? 49.58206 5.15657   15.84196  1.000 17.30791 ? 40  LYS C O   1 
ATOM   2532 C CB  . LYS C 1 40  ? 52.02109 5.24493   14.41812  1.000 17.36561 ? 40  LYS C CB  1 
ATOM   2533 C CG  . LYS C 1 40  ? 53.51466 5.27089   14.13656  1.000 22.17833 ? 40  LYS C CG  1 
ATOM   2534 C CD  . LYS C 1 40  ? 54.29127 5.60586   15.38962  1.000 21.82860 ? 40  LYS C CD  1 
ATOM   2535 C CE  . LYS C 1 40  ? 55.71325 6.03200   15.06377  1.000 23.64780 ? 40  LYS C CE  1 
ATOM   2536 N NZ  . LYS C 1 40  ? 56.53978 6.10044   16.29427  1.000 24.20909 ? 40  LYS C NZ  1 
ATOM   2537 N N   . GLY C 1 41  ? 49.32977 2.96935   15.37885  1.000 16.82206 ? 41  GLY C N   1 
ATOM   2538 C CA  . GLY C 1 41  ? 48.02692 2.87209   16.00104  1.000 15.68331 ? 41  GLY C CA  1 
ATOM   2539 C C   . GLY C 1 41  ? 46.82693 3.19944   15.14124  1.000 14.17246 ? 41  GLY C C   1 
ATOM   2540 O O   . GLY C 1 41  ? 45.70019 3.09550   15.63694  1.000 14.69663 ? 41  GLY C O   1 
ATOM   2541 N N   . LEU C 1 42  ? 47.01555 3.56496   13.88142  1.000 14.35252 ? 42  LEU C N   1 
ATOM   2542 C CA  . LEU C 1 42  ? 45.89005 3.96619   13.05257  1.000 14.68091 ? 42  LEU C CA  1 
ATOM   2543 C C   . LEU C 1 42  ? 45.66206 2.94688   11.94052  1.000 17.46911 ? 42  LEU C C   1 
ATOM   2544 O O   . LEU C 1 42  ? 46.51643 2.10397   11.64123  1.000 18.82901 ? 42  LEU C O   1 
ATOM   2545 C CB  . LEU C 1 42  ? 46.15305 5.34397   12.43563  1.000 16.98797 ? 42  LEU C CB  1 
ATOM   2546 C CG  . LEU C 1 42  ? 46.29769 6.53485   13.38908  1.000 16.04971 ? 42  LEU C CG  1 
ATOM   2547 C CD1 . LEU C 1 42  ? 46.35432 7.85098   12.60440  1.000 18.09547 ? 42  LEU C CD1 1 
ATOM   2548 C CD2 . LEU C 1 42  ? 45.21155 6.60620   14.44654  1.000 18.87502 ? 42  LEU C CD2 1 
ATOM   2549 N N   . GLN C 1 43  ? 44.48551 3.03735   11.33233  1.000 15.65652 ? 43  GLN C N   1 
ATOM   2550 C CA  . GLN C 1 43  ? 44.11832 2.23304   10.18065  1.000 16.27229 ? 43  GLN C CA  1 
ATOM   2551 C C   . GLN C 1 43  ? 43.33058 3.11977   9.23106   1.000 16.68018 ? 43  GLN C C   1 
ATOM   2552 O O   . GLN C 1 43  ? 42.81856 4.17376   9.61421   1.000 16.52020 ? 43  GLN C O   1 
ATOM   2553 C CB  . GLN C 1 43  ? 43.23758 1.03371   10.57334  1.000 16.02057 ? 43  GLN C CB  1 
ATOM   2554 C CG  . GLN C 1 43  ? 41.92882 1.42589   11.26247  1.000 16.95363 ? 43  GLN C CG  1 
ATOM   2555 C CD  . GLN C 1 43  ? 41.01765 0.24340   11.52069  1.000 19.98254 ? 43  GLN C CD  1 
ATOM   2556 O OE1 . GLN C 1 43  ? 41.46829 -0.81637  11.94833  1.000 20.89196 ? 43  GLN C OE1 1 
ATOM   2557 N NE2 . GLN C 1 43  ? 39.72377 0.41985   11.25415  1.000 20.91611 ? 43  GLN C NE2 1 
ATOM   2558 N N   . VAL C 1 44  ? 43.24420 2.68214   7.98157   1.000 17.64458 ? 44  VAL C N   1 
ATOM   2559 C CA  . VAL C 1 44  ? 42.41824 3.35449   6.98576   1.000 17.36306 ? 44  VAL C CA  1 
ATOM   2560 C C   . VAL C 1 44  ? 41.66418 2.29135   6.19734   1.000 22.93559 ? 44  VAL C C   1 
ATOM   2561 O O   . VAL C 1 44  ? 42.26694 1.34327   5.68597   1.000 22.15966 ? 44  VAL C O   1 
ATOM   2562 C CB  . VAL C 1 44  ? 43.24484 4.29729   6.08543   1.000 19.39104 ? 44  VAL C CB  1 
ATOM   2563 C CG1 . VAL C 1 44  ? 44.37359 3.55022   5.37357   1.000 24.32153 ? 44  VAL C CG1 1 
ATOM   2564 C CG2 . VAL C 1 44  ? 42.32972 4.99680   5.08192   1.000 22.93562 ? 44  VAL C CG2 1 
ATOM   2565 N N   . THR C 1 45  ? 40.34411 2.42228   6.14877   1.000 23.69991 ? 45  THR C N   1 
ATOM   2566 C CA  . THR C 1 45  ? 39.48360 1.53344   5.38487   1.000 28.90449 ? 45  THR C CA  1 
ATOM   2567 C C   . THR C 1 45  ? 38.63413 2.38482   4.45965   1.000 27.00589 ? 45  THR C C   1 
ATOM   2568 O O   . THR C 1 45  ? 38.65009 3.61362   4.53168   1.000 24.86667 ? 45  THR C O   1 
ATOM   2569 C CB  . THR C 1 45  ? 38.59095 0.68735   6.30517   1.000 27.23506 ? 45  THR C CB  1 
ATOM   2570 O OG1 . THR C 1 45  ? 37.59886 1.51222   6.93294   1.000 30.81234 ? 45  THR C OG1 1 
ATOM   2571 C CG2 . THR C 1 45  ? 39.43720 -0.00778  7.37154   1.000 30.28838 ? 45  THR C CG2 1 
ATOM   2572 N N   . SER C 1 46  ? 37.87118 1.71966   3.59001   1.000 31.16550 ? 46  SER C N   1 
ATOM   2573 C CA  . SER C 1 46  ? 36.89320 2.44785   2.79158   1.000 28.98310 ? 46  SER C CA  1 
ATOM   2574 C C   . SER C 1 46  ? 35.92649 3.24041   3.66067   1.000 28.31363 ? 46  SER C C   1 
ATOM   2575 O O   . SER C 1 46  ? 35.33921 4.21630   3.18362   1.000 28.25088 ? 46  SER C O   1 
ATOM   2576 C CB  . SER C 1 46  ? 36.15150 1.49386   1.85165   1.000 32.27772 ? 46  SER C CB  1 
ATOM   2577 O OG  . SER C 1 46  ? 35.55790 0.43670   2.57682   1.000 35.77395 ? 46  SER C OG  1 
ATOM   2578 N N   . ASN C 1 47  ? 35.77268 2.86415   4.92995   1.000 26.33279 ? 47  ASN C N   1 
ATOM   2579 C CA  . ASN C 1 47  ? 34.96359 3.61564   5.87608   1.000 27.12185 ? 47  ASN C CA  1 
ATOM   2580 C C   . ASN C 1 47  ? 35.69003 4.80645   6.49766   1.000 26.19766 ? 47  ASN C C   1 
ATOM   2581 O O   . ASN C 1 47  ? 35.05069 5.59191   7.19913   1.000 25.58257 ? 47  ASN C O   1 
ATOM   2582 C CB  . ASN C 1 47  ? 34.46935 2.69197   6.98998   1.000 29.39461 ? 47  ASN C CB  1 
ATOM   2583 C CG  . ASN C 1 47  ? 33.27138 1.86864   6.57091   1.000 37.58717 ? 47  ASN C CG  1 
ATOM   2584 O OD1 . ASN C 1 47  ? 33.12592 1.51796   5.39881   1.000 37.89998 ? 47  ASN C OD1 1 
ATOM   2585 N ND2 . ASN C 1 47  ? 32.40495 1.55345   7.52779   1.000 38.90896 ? 47  ASN C ND2 1 
ATOM   2586 N N   . GLY C 1 48  ? 37.00590 4.94474   6.30521   1.000 22.08061 ? 48  GLY C N   1 
ATOM   2587 C CA  . GLY C 1 48  ? 37.69216 6.13125   6.77551   1.000 20.36044 ? 48  GLY C CA  1 
ATOM   2588 C C   . GLY C 1 48  ? 38.85755 5.79813   7.69363   1.000 19.38849 ? 48  GLY C C   1 
ATOM   2589 O O   . GLY C 1 48  ? 39.21027 4.63255   7.90545   1.000 21.76003 ? 48  GLY C O   1 
ATOM   2590 N N   . VAL C 1 49  ? 39.46656 6.84824   8.25028   1.000 17.89739 ? 49  VAL C N   1 
ATOM   2591 C CA  . VAL C 1 49  ? 40.62229 6.72014   9.14008   1.000 17.37072 ? 49  VAL C CA  1 
ATOM   2592 C C   . VAL C 1 49  ? 40.12860 6.49370   10.56225  1.000 18.78299 ? 49  VAL C C   1 
ATOM   2593 O O   . VAL C 1 49  ? 39.12609 7.07780   10.98590  1.000 17.92203 ? 49  VAL C O   1 
ATOM   2594 C CB  . VAL C 1 49  ? 41.50693 7.98116   9.06362   1.000 14.83014 ? 49  VAL C CB  1 
ATOM   2595 C CG1 . VAL C 1 49  ? 42.82705 7.76458   9.81722   1.000 16.42719 ? 49  VAL C CG1 1 
ATOM   2596 C CG2 . VAL C 1 49  ? 41.78576 8.37782   7.62010   1.000 18.92549 ? 49  VAL C CG2 1 
ATOM   2597 N N   . GLY C 1 50  ? 40.84507 5.65847   11.31816  1.000 15.36439 ? 50  GLY C N   1 
ATOM   2598 C CA  . GLY C 1 50  ? 40.45665 5.39580   12.69583  1.000 15.84997 ? 50  GLY C CA  1 
ATOM   2599 C C   . GLY C 1 50  ? 41.60335 4.78195   13.46586  1.000 15.78006 ? 50  GLY C C   1 
ATOM   2600 O O   . GLY C 1 50  ? 42.63591 4.43010   12.89871  1.000 15.72970 ? 50  GLY C O   1 
ATOM   2601 N N   . LEU C 1 51  ? 41.41950 4.66905   14.77696  1.000 15.43634 ? 51  LEU C N   1 
ATOM   2602 C CA  . LEU C 1 51  ? 42.34219 3.87177   15.57637  1.000 14.55493 ? 51  LEU C CA  1 
ATOM   2603 C C   . LEU C 1 51  ? 42.16347 2.40727   15.21053  1.000 17.39117 ? 51  LEU C C   1 
ATOM   2604 O O   . LEU C 1 51  ? 41.04452 1.96325   14.93527  1.000 17.26409 ? 51  LEU C O   1 
ATOM   2605 C CB  . LEU C 1 51  ? 42.01692 4.04398   17.05623  1.000 15.48445 ? 51  LEU C CB  1 
ATOM   2606 C CG  . LEU C 1 51  ? 42.29296 5.42599   17.63866  1.000 18.96865 ? 51  LEU C CG  1 
ATOM   2607 C CD1 . LEU C 1 51  ? 41.63435 5.60491   18.99292  1.000 18.60758 ? 51  LEU C CD1 1 
ATOM   2608 C CD2 . LEU C 1 51  ? 43.78482 5.58003   17.75631  1.000 21.01509 ? 51  LEU C CD2 1 
ATOM   2609 N N   . ASN C 1 52  ? 43.26881 1.65631   15.20834  1.000 16.50571 ? 52  ASN C N   1 
ATOM   2610 C CA  . ASN C 1 52  ? 43.18750 0.21508   15.02499  1.000 18.08082 ? 52  ASN C CA  1 
ATOM   2611 C C   . ASN C 1 52  ? 42.95908 -0.46529  16.37070  1.000 18.25146 ? 52  ASN C C   1 
ATOM   2612 O O   . ASN C 1 52  ? 42.86343 0.18696   17.41593  1.000 18.13678 ? 52  ASN C O   1 
ATOM   2613 C CB  . ASN C 1 52  ? 44.38732 -0.31539  14.23317  1.000 17.18476 ? 52  ASN C CB  1 
ATOM   2614 C CG  . ASN C 1 52  ? 45.71039 -0.21064  14.99088  1.000 18.31281 ? 52  ASN C CG  1 
ATOM   2615 O OD1 . ASN C 1 52  ? 45.76206 -0.31133  16.22189  1.000 19.27873 ? 52  ASN C OD1 1 
ATOM   2616 N ND2 . ASN C 1 52  ? 46.78237 0.02640   14.25348  1.000 17.85168 ? 52  ASN C ND2 1 
ATOM   2617 N N   . ASN C 1 53  ? 42.87750 -1.80358  16.34821  1.000 19.39310 ? 53  ASN C N   1 
ATOM   2618 C CA  . ASN C 1 53  ? 42.47505 -2.54112  17.53934  1.000 19.82114 ? 53  ASN C CA  1 
ATOM   2619 C C   . ASN C 1 53  ? 43.60758 -2.77078  18.52451  1.000 18.55910 ? 53  ASN C C   1 
ATOM   2620 O O   . ASN C 1 53  ? 43.35519 -3.31768  19.60695  1.000 21.56960 ? 53  ASN C O   1 
ATOM   2621 C CB  . ASN C 1 53  ? 41.86276 -3.89493  17.17281  1.000 23.07327 ? 53  ASN C CB  1 
ATOM   2622 C CG  . ASN C 1 53  ? 40.49263 -3.76500  16.58538  1.000 28.30439 ? 53  ASN C CG  1 
ATOM   2623 O OD1 . ASN C 1 53  ? 39.80764 -2.76421  16.79616  1.000 29.91680 ? 53  ASN C OD1 1 
ATOM   2624 N ND2 . ASN C 1 53  ? 40.06873 -4.78423  15.84611  1.000 31.71028 ? 53  ASN C ND2 1 
ATOM   2625 N N   . THR C 1 54  ? 44.83769 -2.38854  18.18064  1.000 18.69410 ? 54  THR C N   1 
ATOM   2626 C CA  . THR C 1 54  ? 45.96793 -2.55005  19.08443  1.000 19.22886 ? 54  THR C CA  1 
ATOM   2627 C C   . THR C 1 54  ? 46.61318 -1.22196  19.46435  1.000 17.82458 ? 54  THR C C   1 
ATOM   2628 O O   . THR C 1 54  ? 47.65264 -1.21737  20.12506  1.000 16.91085 ? 54  THR C O   1 
ATOM   2629 C CB  . THR C 1 54  ? 46.99551 -3.51604  18.49523  1.000 20.91037 ? 54  THR C CB  1 
ATOM   2630 O OG1 . THR C 1 54  ? 47.48107 -2.99860  17.25252  1.000 23.00048 ? 54  THR C OG1 1 
ATOM   2631 C CG2 . THR C 1 54  ? 46.36232 -4.89876  18.28142  1.000 23.78949 ? 54  THR C CG2 1 
ATOM   2632 N N   . ALA C 1 55  ? 46.00869 -0.09231  19.08825  1.000 16.00399 ? 55  ALA C N   1 
ATOM   2633 C CA  . ALA C 1 55  ? 46.53513 1.19885   19.50887  1.000 15.50721 ? 55  ALA C CA  1 
ATOM   2634 C C   . ALA C 1 55  ? 46.67152 1.30035   21.02424  1.000 13.83395 ? 55  ALA C C   1 
ATOM   2635 O O   . ALA C 1 55  ? 47.53600 2.03316   21.51738  1.000 15.87260 ? 55  ALA C O   1 
ATOM   2636 C CB  . ALA C 1 55  ? 45.61416 2.30596   19.00638  1.000 17.52890 ? 55  ALA C CB  1 
ATOM   2637 N N   . TRP C 1 56  ? 45.82246 0.59308   21.77743  1.000 15.97155 ? 56  TRP C N   1 
ATOM   2638 C CA  . TRP C 1 56  ? 45.88827 0.67215   23.23311  1.000 14.76291 ? 56  TRP C CA  1 
ATOM   2639 C C   . TRP C 1 56  ? 47.23565 0.20233   23.77497  1.000 14.41335 ? 56  TRP C C   1 
ATOM   2640 O O   . TRP C 1 56  ? 47.66233 0.66453   24.83450  1.000 14.14638 ? 56  TRP C O   1 
ATOM   2641 C CB  . TRP C 1 56  ? 44.72763 -0.11202  23.85816  1.000 14.07614 ? 56  TRP C CB  1 
ATOM   2642 C CG  . TRP C 1 56  ? 44.77847 -1.58665  23.58788  1.000 14.51089 ? 56  TRP C CG  1 
ATOM   2643 C CD1 . TRP C 1 56  ? 44.17869 -2.24811  22.55556  1.000 15.42162 ? 56  TRP C CD1 1 
ATOM   2644 C CD2 . TRP C 1 56  ? 45.45268 -2.58694  24.36679  1.000 14.72802 ? 56  TRP C CD2 1 
ATOM   2645 N NE1 . TRP C 1 56  ? 44.45932 -3.59492  22.62748  1.000 17.44892 ? 56  TRP C NE1 1 
ATOM   2646 C CE2 . TRP C 1 56  ? 45.22361 -3.83217  23.73914  1.000 16.05576 ? 56  TRP C CE2 1 
ATOM   2647 C CE3 . TRP C 1 56  ? 46.20625 -2.55518  25.54444  1.000 16.80413 ? 56  TRP C CE3 1 
ATOM   2648 C CZ2 . TRP C 1 56  ? 45.73547 -5.03566  24.24487  1.000 16.79836 ? 56  TRP C CZ2 1 
ATOM   2649 C CZ3 . TRP C 1 56  ? 46.71541 -3.74983  26.04209  1.000 17.82682 ? 56  TRP C CZ3 1 
ATOM   2650 C CH2 . TRP C 1 56  ? 46.48081 -4.96939  25.39240  1.000 17.36507 ? 56  TRP C CH2 1 
ATOM   2651 N N   . ILE C 1 57  ? 47.91333 -0.71182  23.07014  1.000 13.38207 ? 57  ILE C N   1 
ATOM   2652 C CA  . ILE C 1 57  ? 49.23291 -1.17188  23.50733  1.000 12.83584 ? 57  ILE C CA  1 
ATOM   2653 C C   . ILE C 1 57  ? 50.22462 -0.01310  23.52353  1.000 14.76247 ? 57  ILE C C   1 
ATOM   2654 O O   . ILE C 1 57  ? 50.96033 0.18587   24.50153  1.000 13.73812 ? 57  ILE C O   1 
ATOM   2655 C CB  . ILE C 1 57  ? 49.71530 -2.33362  22.61899  1.000 14.41858 ? 57  ILE C CB  1 
ATOM   2656 C CG1 . ILE C 1 57  ? 48.77318 -3.53352  22.78369  1.000 16.72065 ? 57  ILE C CG1 1 
ATOM   2657 C CG2 . ILE C 1 57  ? 51.16962 -2.67694  22.92445  1.000 14.96071 ? 57  ILE C CG2 1 
ATOM   2658 C CD1 . ILE C 1 57  ? 49.08379 -4.71688  21.87032  1.000 17.20784 ? 57  ILE C CD1 1 
ATOM   2659 N N   . LYS C 1 58  ? 50.26005 0.77128   22.43962  1.000 15.09687 ? 58  LYS C N   1 
ATOM   2660 C CA  . LYS C 1 58  ? 51.14558 1.93532   22.39450  1.000 14.47409 ? 58  LYS C CA  1 
ATOM   2661 C C   . LYS C 1 58  ? 50.82946 2.89824   23.53115  1.000 14.52254 ? 58  LYS C C   1 
ATOM   2662 O O   . LYS C 1 58  ? 51.73724 3.48606   24.13799  1.000 15.10651 ? 58  LYS C O   1 
ATOM   2663 C CB  . LYS C 1 58  ? 51.00023 2.63720   21.04296  1.000 16.90229 ? 58  LYS C CB  1 
ATOM   2664 C CG  . LYS C 1 58  ? 51.94859 3.81472   20.85367  1.000 17.71162 ? 58  LYS C CG  1 
ATOM   2665 C CD  . LYS C 1 58  ? 51.91442 4.34730   19.42613  1.000 18.81251 ? 58  LYS C CD  1 
ATOM   2666 C CE  . LYS C 1 58  ? 52.56214 5.71026   19.33736  1.000 19.81753 ? 58  LYS C CE  1 
ATOM   2667 N NZ  . LYS C 1 58  ? 54.03081 5.61706   19.56328  1.000 21.77645 ? 58  LYS C NZ  1 
ATOM   2668 N N   . MET C 1 59  ? 49.54140 3.06199   23.83823  1.000 15.04919 ? 59  MET C N   1 
ATOM   2669 C CA  . MET C 1 59  ? 49.11835 3.98575   24.88310  1.000 15.01536 ? 59  MET C CA  1 
ATOM   2670 C C   . MET C 1 59  ? 49.63555 3.52937   26.24201  1.000 15.23659 ? 59  MET C C   1 
ATOM   2671 O O   . MET C 1 59  ? 50.19503 4.32558   27.00028  1.000 14.44481 ? 59  MET C O   1 
ATOM   2672 C CB  . MET C 1 59  ? 47.59490 4.05906   24.86488  1.000 17.59036 ? 59  MET C CB  1 
ATOM   2673 C CG  . MET C 1 59  ? 47.06495 4.76003   23.61543  1.000 21.23901 ? 59  MET C CG  1 
ATOM   2674 S SD  . MET C 1 59  ? 47.76357 6.37756   23.21558  0.536 16.87391 ? 59  MET C SD  1 
ATOM   2675 C CE  . MET C 1 59  ? 48.93551 5.99070   21.92311  1.000 24.26241 ? 59  MET C CE  1 
ATOM   2676 N N   . MET C 1 60  ? 49.48303 2.23560   26.55334  1.000 14.85527 ? 60  MET C N   1 
ATOM   2677 C CA  . MET C 1 60  ? 49.92221 1.72493   27.85162  1.000 14.84373 ? 60  MET C CA  1 
ATOM   2678 C C   . MET C 1 60  ? 51.44199 1.68906   27.96804  1.000 13.91607 ? 60  MET C C   1 
ATOM   2679 O O   . MET C 1 60  ? 51.99166 1.91425   29.05453  1.000 13.74985 ? 60  MET C O   1 
ATOM   2680 C CB  . MET C 1 60  ? 49.32200 0.34671   28.12054  1.000 14.59813 ? 60  MET C CB  1 
ATOM   2681 C CG  . MET C 1 60  ? 47.80528 0.26290   28.11847  1.000 15.47229 ? 60  MET C CG  1 
ATOM   2682 S SD  . MET C 1 60  ? 47.09505 1.39465   29.32163  0.883 16.37742 ? 60  MET C SD  1 
ATOM   2683 C CE  . MET C 1 60  ? 47.45830 0.52306   30.83914  1.000 18.73776 ? 60  MET C CE  1 
ATOM   2684 N N   . CYS C 1 61  ? 52.14592 1.38612   26.87542  1.000 13.65121 ? 61  CYS C N   1 
ATOM   2685 C CA  . CYS C 1 61  ? 53.60192 1.48598   26.92496  1.000 14.74504 ? 61  CYS C CA  1 
ATOM   2686 C C   . CYS C 1 61  ? 54.03448 2.91479   27.20591  1.000 15.92843 ? 61  CYS C C   1 
ATOM   2687 O O   . CYS C 1 61  ? 54.97898 3.15333   27.96838  1.000 14.91576 ? 61  CYS C O   1 
ATOM   2688 C CB  . CYS C 1 61  ? 54.21566 0.99428   25.61544  1.000 15.59936 ? 61  CYS C CB  1 
ATOM   2689 S SG  . CYS C 1 61  ? 54.18435 -0.79569  25.36983  0.821 15.69411 ? 61  CYS C SG  1 
ATOM   2690 N N   . GLY C 1 62  ? 53.35564 3.88280   26.59609  1.000 14.26642 ? 62  GLY C N   1 
ATOM   2691 C CA  . GLY C 1 62  ? 53.64456 5.27311   26.90157  1.000 14.20107 ? 62  GLY C CA  1 
ATOM   2692 C C   . GLY C 1 62  ? 53.33027 5.63164   28.34034  1.000 14.84462 ? 62  GLY C C   1 
ATOM   2693 O O   . GLY C 1 62  ? 54.11156 6.31290   29.00519  1.000 15.86192 ? 62  GLY C O   1 
ATOM   2694 N N   . LEU C 1 63  ? 52.19320 5.15837   28.84588  1.000 13.71744 ? 63  LEU C N   1 
ATOM   2695 C CA  . LEU C 1 63  ? 51.79209 5.46147   30.21713  1.000 14.47067 ? 63  LEU C CA  1 
ATOM   2696 C C   . LEU C 1 63  ? 52.89376 5.13745   31.21388  1.000 15.82414 ? 63  LEU C C   1 
ATOM   2697 O O   . LEU C 1 63  ? 53.21797 5.95153   32.08478  1.000 14.78742 ? 63  LEU C O   1 
ATOM   2698 C CB  . LEU C 1 63  ? 50.53445 4.66841   30.56535  1.000 14.85913 ? 63  LEU C CB  1 
ATOM   2699 C CG  . LEU C 1 63  ? 50.08790 4.67914   32.03210  1.000 14.63909 ? 63  LEU C CG  1 
ATOM   2700 C CD1 . LEU C 1 63  ? 49.83469 6.10886   32.48734  1.000 14.76841 ? 63  LEU C CD1 1 
ATOM   2701 C CD2 . LEU C 1 63  ? 48.84587 3.80965   32.22761  1.000 13.33125 ? 63  LEU C CD2 1 
ATOM   2702 N N   . HIS C 1 64  ? 53.48852 3.94908   31.09947  1.000 13.34796 ? 64  HIS C N   1 
ATOM   2703 C CA  . HIS C 1 64  ? 54.48851 3.50574   32.05991  1.000 13.43044 ? 64  HIS C CA  1 
ATOM   2704 C C   . HIS C 1 64  ? 55.91868 3.71074   31.58575  1.000 14.08782 ? 64  HIS C C   1 
ATOM   2705 O O   . HIS C 1 64  ? 56.85692 3.40202   32.33646  1.000 13.96819 ? 64  HIS C O   1 
ATOM   2706 C CB  . HIS C 1 64  ? 54.23926 2.03886   32.42857  1.000 13.52541 ? 64  HIS C CB  1 
ATOM   2707 C CG  . HIS C 1 64  ? 52.94744 1.82863   33.14429  1.000 12.88424 ? 64  HIS C CG  1 
ATOM   2708 N ND1 . HIS C 1 64  ? 52.69480 2.38384   34.37989  1.000 13.35972 ? 64  HIS C ND1 1 
ATOM   2709 C CD2 . HIS C 1 64  ? 51.82306 1.15912   32.79177  1.000 14.30851 ? 64  HIS C CD2 1 
ATOM   2710 C CE1 . HIS C 1 64  ? 51.47312 2.05030   34.76424  1.000 14.68185 ? 64  HIS C CE1 1 
ATOM   2711 N NE2 . HIS C 1 64  ? 50.93044 1.30102   33.82451  1.000 15.58352 ? 64  HIS C NE2 1 
ATOM   2712 N N   . ASN C 1 65  ? 56.11086 4.24904   30.37974  1.000 13.37213 ? 65  ASN C N   1 
ATOM   2713 C CA  . ASN C 1 65  ? 57.43105 4.33371   29.76540  1.000 14.92128 ? 65  ASN C CA  1 
ATOM   2714 C C   . ASN C 1 65  ? 58.06697 2.94819   29.69479  1.000 15.25922 ? 65  ASN C C   1 
ATOM   2715 O O   . ASN C 1 65  ? 59.24449 2.76801   29.99823  1.000 16.79023 ? 65  ASN C O   1 
ATOM   2716 C CB  . ASN C 1 65  ? 58.33348 5.34417   30.48245  1.000 16.76321 ? 65  ASN C CB  1 
ATOM   2717 C CG  . ASN C 1 65  ? 59.38932 5.91976   29.57930  1.000 22.30784 ? 65  ASN C CG  1 
ATOM   2718 O OD1 . ASN C 1 65  ? 59.20864 6.00158   28.36115  1.000 24.93865 ? 65  ASN C OD1 1 
ATOM   2719 N ND2 . ASN C 1 65  ? 60.50359 6.34641   30.17177  1.000 23.24678 ? 65  ASN C ND2 1 
ATOM   2720 N N   . ALA C 1 66  ? 57.25751 1.95322   29.32266  1.000 13.24714 ? 66  ALA C N   1 
ATOM   2721 C CA  . ALA C 1 66  ? 57.69437 0.56663   29.21557  1.000 13.20943 ? 66  ALA C CA  1 
ATOM   2722 C C   . ALA C 1 66  ? 58.32560 0.32122   27.85079  1.000 15.67627 ? 66  ALA C C   1 
ATOM   2723 O O   . ALA C 1 66  ? 57.88287 0.87546   26.84269  1.000 18.48761 ? 66  ALA C O   1 
ATOM   2724 C CB  . ALA C 1 66  ? 56.50195 -0.37347  29.38250  1.000 13.19486 ? 66  ALA C CB  1 
ATOM   2725 N N   . THR C 1 67  ? 59.34600 -0.53813  27.81864  1.000 14.18748 ? 67  THR C N   1 
ATOM   2726 C CA  . THR C 1 67  ? 60.02891 -0.85509  26.56929  1.000 13.01111 ? 67  THR C CA  1 
ATOM   2727 C C   . THR C 1 67  ? 59.68127 -2.23519  26.02441  1.000 13.21121 ? 67  THR C C   1 
ATOM   2728 O O   . THR C 1 67  ? 60.03323 -2.53585  24.87463  1.000 14.50722 ? 67  THR C O   1 
ATOM   2729 C CB  . THR C 1 67  ? 61.55908 -0.71658  26.71829  1.000 15.72154 ? 67  THR C CB  1 
ATOM   2730 O OG1 . THR C 1 67  ? 61.98809 -1.40874  27.89017  1.000 16.78001 ? 67  THR C OG1 1 
ATOM   2731 C CG2 . THR C 1 67  ? 61.95755 0.76012   26.82599  1.000 17.00694 ? 67  THR C CG2 1 
ATOM   2732 N N   . PHE C 1 68  ? 59.00604 -3.07008  26.81156  1.000 12.13414 ? 68  PHE C N   1 
ATOM   2733 C CA  . PHE C 1 68  ? 58.57411 -4.39433  26.38749  1.000 11.47676 ? 68  PHE C CA  1 
ATOM   2734 C C   . PHE C 1 68  ? 57.23420 -4.65792  27.03520  1.000 14.67548 ? 68  PHE C C   1 
ATOM   2735 O O   . PHE C 1 68  ? 56.89759 -4.04312  28.04508  1.000 13.66264 ? 68  PHE C O   1 
ATOM   2736 C CB  . PHE C 1 68  ? 59.58035 -5.48265  26.80042  1.000 12.44161 ? 68  PHE C CB  1 
ATOM   2737 C CG  . PHE C 1 68  ? 60.93434 -5.25702  26.21286  1.000 12.67395 ? 68  PHE C CG  1 
ATOM   2738 C CD1 . PHE C 1 68  ? 61.20518 -5.68573  24.92706  1.000 12.50420 ? 68  PHE C CD1 1 
ATOM   2739 C CD2 . PHE C 1 68  ? 61.90131 -4.53612  26.90534  1.000 13.78280 ? 68  PHE C CD2 1 
ATOM   2740 C CE1 . PHE C 1 68  ? 62.44929 -5.43587  24.34861  1.000 14.51575 ? 68  PHE C CE1 1 
ATOM   2741 C CE2 . PHE C 1 68  ? 63.14620 -4.29301  26.33591  1.000 15.95039 ? 68  PHE C CE2 1 
ATOM   2742 C CZ  . PHE C 1 68  ? 63.40630 -4.74161  25.05426  1.000 17.50910 ? 68  PHE C CZ  1 
ATOM   2743 N N   . TYR C 1 69  ? 56.47251 -5.56738  26.43591  1.000 12.51440 ? 69  TYR C N   1 
ATOM   2744 C CA  . TYR C 1 69  ? 55.15545 -5.91711  26.95411  1.000 12.79869 ? 69  TYR C CA  1 
ATOM   2745 C C   . TYR C 1 69  ? 54.79935 -7.34118  26.54739  1.000 13.49724 ? 69  TYR C C   1 
ATOM   2746 O O   . TYR C 1 69  ? 55.41807 -7.93450  25.65763  1.000 13.32675 ? 69  TYR C O   1 
ATOM   2747 C CB  . TYR C 1 69  ? 54.07119 -4.92963  26.46444  1.000 15.24393 ? 69  TYR C CB  1 
ATOM   2748 C CG  . TYR C 1 69  ? 53.68430 -5.17524  25.02551  1.000 14.62842 ? 69  TYR C CG  1 
ATOM   2749 C CD1 . TYR C 1 69  ? 54.47618 -4.69646  23.98218  1.000 14.76494 ? 69  TYR C CD1 1 
ATOM   2750 C CD2 . TYR C 1 69  ? 52.55813 -5.93430  24.71331  1.000 14.60999 ? 69  TYR C CD2 1 
ATOM   2751 C CE1 . TYR C 1 69  ? 54.14958 -4.96359  22.67014  1.000 17.97801 ? 69  TYR C CE1 1 
ATOM   2752 C CE2 . TYR C 1 69  ? 52.22025 -6.19096  23.40941  1.000 15.95247 ? 69  TYR C CE2 1 
ATOM   2753 C CZ  . TYR C 1 69  ? 53.01907 -5.70150  22.39218  1.000 16.57205 ? 69  TYR C CZ  1 
ATOM   2754 O OH  . TYR C 1 69  ? 52.66969 -5.96489  21.08898  1.000 21.88235 ? 69  TYR C OH  1 
ATOM   2755 N N   . VAL C 1 70  ? 53.77156 -7.88379  27.21055  1.000 13.91043 ? 70  VAL C N   1 
ATOM   2756 C CA  . VAL C 1 70  ? 53.06620 -9.07517  26.75477  1.000 14.00649 ? 70  VAL C CA  1 
ATOM   2757 C C   . VAL C 1 70  ? 51.57537 -8.77621  26.77811  1.000 14.15536 ? 70  VAL C C   1 
ATOM   2758 O O   . VAL C 1 70  ? 51.10388 -7.91450  27.52508  1.000 15.09989 ? 70  VAL C O   1 
ATOM   2759 C CB  . VAL C 1 70  ? 53.34227 -10.33955 27.60532  1.000 14.14645 ? 70  VAL C CB  1 
ATOM   2760 C CG1 . VAL C 1 70  ? 54.81719 -10.69289 27.60410  1.000 14.11587 ? 70  VAL C CG1 1 
ATOM   2761 C CG2 . VAL C 1 70  ? 52.85049 -10.15165 29.03079  1.000 16.51463 ? 70  VAL C CG2 1 
ATOM   2762 N N   . SER C 1 71  ? 50.83032 -9.50937  25.94645  1.000 15.44166 ? 71  SER C N   1 
ATOM   2763 C CA  . SER C 1 71  ? 49.37386 -9.46952  26.01032  1.000 16.74386 ? 71  SER C CA  1 
ATOM   2764 C C   . SER C 1 71  ? 48.81405 -10.78957 25.51297  1.000 19.29297 ? 71  SER C C   1 
ATOM   2765 O O   . SER C 1 71  ? 49.19252 -11.26619 24.43682  1.000 20.10589 ? 71  SER C O   1 
ATOM   2766 C CB  . SER C 1 71  ? 48.80467 -8.33050  25.16620  1.000 16.46519 ? 71  SER C CB  1 
ATOM   2767 O OG  . SER C 1 71  ? 47.38387 -8.27774  25.29182  1.000 19.20916 ? 71  SER C OG  1 
ATOM   2768 N N   . ASP C 1 72  ? 47.92475 -11.38179 26.30297  1.000 17.76737 ? 72  ASP C N   1 
ATOM   2769 C CA  . ASP C 1 72  ? 47.15614 -12.53177 25.84640  1.000 19.95626 ? 72  ASP C CA  1 
ATOM   2770 C C   . ASP C 1 72  ? 45.73221 -12.37559 26.36490  1.000 21.12030 ? 72  ASP C C   1 
ATOM   2771 O O   . ASP C 1 72  ? 45.34811 -11.31254 26.86039  1.000 19.47112 ? 72  ASP C O   1 
ATOM   2772 C CB  . ASP C 1 72  ? 47.85413 -13.86216 26.16633  1.000 22.31848 ? 72  ASP C CB  1 
ATOM   2773 C CG  . ASP C 1 72  ? 47.80054 -14.22655 27.63759  1.000 22.69544 ? 72  ASP C CG  1 
ATOM   2774 O OD1 . ASP C 1 72  ? 47.13523 -13.52445 28.43522  1.000 21.11539 ? 72  ASP C OD1 1 
ATOM   2775 O OD2 . ASP C 1 72  ? 48.42140 -15.25201 27.99265  1.000 24.70189 ? 72  ASP C OD2 1 
ATOM   2776 N N   . THR C 1 73  ? 44.93846 -13.44273 26.27489  1.000 22.15571 ? 73  THR C N   1 
ATOM   2777 C CA  . THR C 1 73  ? 43.53547 -13.28744 26.64965  1.000 21.35634 ? 73  THR C CA  1 
ATOM   2778 C C   . THR C 1 73  ? 43.31983 -13.07699 28.14892  1.000 19.62063 ? 73  THR C C   1 
ATOM   2779 O O   . THR C 1 73  ? 42.23790 -12.62227 28.53738  1.000 20.57058 ? 73  THR C O   1 
ATOM   2780 C CB  . THR C 1 73  ? 42.67634 -14.43608 26.10452  1.000 27.91357 ? 73  THR C CB  1 
ATOM   2781 O OG1 . THR C 1 73  ? 43.30432 -15.68248 26.40415  1.000 32.25727 ? 73  THR C OG1 1 
ATOM   2782 C CG2 . THR C 1 73  ? 42.50153 -14.30106 24.59719  1.000 30.37327 ? 73  THR C CG2 1 
ATOM   2783 N N   . TYR C 1 74  ? 44.31481 -13.35417 28.99146  1.000 18.60661 ? 74  TYR C N   1 
ATOM   2784 C CA  . TYR C 1 74  ? 44.14441 -13.29322 30.43772  1.000 18.37693 ? 74  TYR C CA  1 
ATOM   2785 C C   . TYR C 1 74  ? 44.77436 -12.06611 31.08172  1.000 17.21791 ? 74  TYR C C   1 
ATOM   2786 O O   . TYR C 1 74  ? 44.35709 -11.67968 32.18092  1.000 17.47390 ? 74  TYR C O   1 
ATOM   2787 C CB  . TYR C 1 74  ? 44.74274 -14.54760 31.08699  1.000 24.82620 ? 74  TYR C CB  1 
ATOM   2788 C CG  . TYR C 1 74  ? 44.07000 -15.83840 30.67769  1.000 24.47032 ? 74  TYR C CG  1 
ATOM   2789 C CD1 . TYR C 1 74  ? 42.98980 -16.33158 31.38755  1.000 26.90983 ? 74  TYR C CD1 1 
ATOM   2790 C CD2 . TYR C 1 74  ? 44.50211 -16.54305 29.56401  1.000 26.38030 ? 74  TYR C CD2 1 
ATOM   2791 C CE1 . TYR C 1 74  ? 42.37234 -17.51589 31.01473  1.000 26.48024 ? 74  TYR C CE1 1 
ATOM   2792 C CE2 . TYR C 1 74  ? 43.88286 -17.71643 29.17484  1.000 29.06736 ? 74  TYR C CE2 1 
ATOM   2793 C CZ  . TYR C 1 74  ? 42.82612 -18.19681 29.90437  1.000 30.23181 ? 74  TYR C CZ  1 
ATOM   2794 O OH  . TYR C 1 74  ? 42.21398 -19.37303 29.52286  1.000 31.03827 ? 74  TYR C OH  1 
ATOM   2795 N N   . VAL C 1 75  ? 45.74825 -11.44114 30.42872  1.000 17.40710 ? 75  VAL C N   1 
ATOM   2796 C CA  . VAL C 1 75  ? 46.58214 -10.44944 31.10392  1.000 16.56644 ? 75  VAL C CA  1 
ATOM   2797 C C   . VAL C 1 75  ? 47.37741 -9.65958  30.07635  1.000 15.05067 ? 75  VAL C C   1 
ATOM   2798 O O   . VAL C 1 75  ? 47.66831 -10.15258 28.98299  1.000 15.55054 ? 75  VAL C O   1 
ATOM   2799 C CB  . VAL C 1 75  ? 47.52866 -11.12680 32.12164  1.000 17.19297 ? 75  VAL C CB  1 
ATOM   2800 C CG1 . VAL C 1 75  ? 48.65737 -11.88639 31.41236  1.000 17.92051 ? 75  VAL C CG1 1 
ATOM   2801 C CG2 . VAL C 1 75  ? 48.09990 -10.11174 33.08914  1.000 16.81462 ? 75  VAL C CG2 1 
ATOM   2802 N N   . CYS C 1 76  ? 47.74108 -8.42964  30.41820  1.000 14.17304 ? 76  CYS C N   1 
ATOM   2803 C CA  . CYS C 1 76  ? 48.82349 -7.74306  29.73082  1.000 15.05270 ? 76  CYS C CA  1 
ATOM   2804 C C   . CYS C 1 76  ? 49.73226 -7.10988  30.76991  1.000 13.80167 ? 76  CYS C C   1 
ATOM   2805 O O   . CYS C 1 76  ? 49.32674 -6.84362  31.90448  1.000 14.07932 ? 76  CYS C O   1 
ATOM   2806 C CB  . CYS C 1 76  ? 48.34969 -6.72730  28.67734  1.000 14.68654 ? 76  CYS C CB  1 
ATOM   2807 S SG  . CYS C 1 76  ? 47.26692 -5.44217  29.34232  0.978 15.23068 ? 76  CYS C SG  1 
ATOM   2808 N N   . VAL C 1 77  ? 50.99309 -6.94805  30.39662  1.000 13.61334 ? 77  VAL C N   1 
ATOM   2809 C CA  . VAL C 1 77  ? 52.03288 -6.55017  31.33444  1.000 14.92139 ? 77  VAL C CA  1 
ATOM   2810 C C   . VAL C 1 77  ? 52.99830 -5.63414  30.60444  1.000 15.17896 ? 77  VAL C C   1 
ATOM   2811 O O   . VAL C 1 77  ? 53.38012 -5.91077  29.46245  1.000 14.73354 ? 77  VAL C O   1 
ATOM   2812 C CB  . VAL C 1 77  ? 52.77374 -7.78701  31.88755  1.000 14.48539 ? 77  VAL C CB  1 
ATOM   2813 C CG1 . VAL C 1 77  ? 53.76769 -7.36205  32.92510  1.000 15.01525 ? 77  VAL C CG1 1 
ATOM   2814 C CG2 . VAL C 1 77  ? 51.80069 -8.80345  32.49263  1.000 17.85007 ? 77  VAL C CG2 1 
ATOM   2815 N N   . PHE C 1 78  ? 53.40290 -4.54892  31.26528  1.000 12.44556 ? 78  PHE C N   1 
ATOM   2816 C CA  . PHE C 1 78  ? 54.27620 -3.54055  30.66955  1.000 11.70697 ? 78  PHE C CA  1 
ATOM   2817 C C   . PHE C 1 78  ? 55.54259 -3.42040  31.50337  1.000 12.95473 ? 78  PHE C C   1 
ATOM   2818 O O   . PHE C 1 78  ? 55.47544 -3.10120  32.69644  1.000 13.11178 ? 78  PHE C O   1 
ATOM   2819 C CB  . PHE C 1 78  ? 53.49990 -2.22556  30.52676  1.000 13.81621 ? 78  PHE C CB  1 
ATOM   2820 C CG  . PHE C 1 78  ? 52.25985 -2.40994  29.70155  1.000 13.05474 ? 78  PHE C CG  1 
ATOM   2821 C CD1 . PHE C 1 78  ? 52.33893 -2.38327  28.32168  1.000 14.13677 ? 78  PHE C CD1 1 
ATOM   2822 C CD2 . PHE C 1 78  ? 51.04772 -2.73293  30.29407  1.000 13.66470 ? 78  PHE C CD2 1 
ATOM   2823 C CE1 . PHE C 1 78  ? 51.21345 -2.62776  27.54335  1.000 15.06094 ? 78  PHE C CE1 1 
ATOM   2824 C CE2 . PHE C 1 78  ? 49.92189 -2.99200  29.51636  1.000 14.41589 ? 78  PHE C CE2 1 
ATOM   2825 C CZ  . PHE C 1 78  ? 50.01268 -2.93622  28.14508  1.000 14.43668 ? 78  PHE C CZ  1 
ATOM   2826 N N   . PHE C 1 79  ? 56.68507 -3.70874  30.87975  1.000 13.64486 ? 79  PHE C N   1 
ATOM   2827 C CA  . PHE C 1 79  ? 57.95215 -3.88066  31.58319  1.000 11.97385 ? 79  PHE C CA  1 
ATOM   2828 C C   . PHE C 1 79  ? 58.85049 -2.66224  31.42272  1.000 13.35215 ? 79  PHE C C   1 
ATOM   2829 O O   . PHE C 1 79  ? 59.05211 -2.17520  30.31157  1.000 12.97744 ? 79  PHE C O   1 
ATOM   2830 C CB  . PHE C 1 79  ? 58.71919 -5.08698  31.02697  1.000 13.53040 ? 79  PHE C CB  1 
ATOM   2831 C CG  . PHE C 1 79  ? 58.01600 -6.40052  31.19951  1.000 13.99247 ? 79  PHE C CG  1 
ATOM   2832 C CD1 . PHE C 1 79  ? 57.08821 -6.82634  30.26308  1.000 13.66818 ? 79  PHE C CD1 1 
ATOM   2833 C CD2 . PHE C 1 79  ? 58.28603 -7.21763  32.30043  1.000 14.78875 ? 79  PHE C CD2 1 
ATOM   2834 C CE1 . PHE C 1 79  ? 56.43719 -8.05301  30.40930  1.000 15.05044 ? 79  PHE C CE1 1 
ATOM   2835 C CE2 . PHE C 1 79  ? 57.63374 -8.45051  32.45401  1.000 15.18215 ? 79  PHE C CE2 1 
ATOM   2836 C CZ  . PHE C 1 79  ? 56.70957 -8.85650  31.51405  1.000 14.79434 ? 79  PHE C CZ  1 
ATOM   2837 N N   . CYS C 1 80  ? 59.45701 -2.24188  32.53172  1.000 13.77568 ? 80  CYS C N   1 
ATOM   2838 C CA  . CYS C 1 80  ? 60.45902 -1.17869  32.56929  1.000 13.79710 ? 80  CYS C CA  1 
ATOM   2839 C C   . CYS C 1 80  ? 61.75901 -1.73945  33.13035  1.000 14.89167 ? 80  CYS C C   1 
ATOM   2840 O O   . CYS C 1 80  ? 61.79076 -2.22968  34.26515  1.000 14.24232 ? 80  CYS C O   1 
ATOM   2841 C CB  . CYS C 1 80  ? 59.98964 -0.04796  33.48116  1.000 13.06810 ? 80  CYS C CB  1 
ATOM   2842 S SG  . CYS C 1 80  ? 58.43316 0.72644   32.96534  0.914 13.75730 ? 80  CYS C SG  1 
ATOM   2843 N N   . ASN C 1 81  ? 62.83541 -1.61837  32.36410  1.000 13.54517 ? 81  ASN C N   1 
ATOM   2844 C CA  . ASN C 1 81  ? 64.14852 -1.98477  32.87614  1.000 15.84474 ? 81  ASN C CA  1 
ATOM   2845 C C   . ASN C 1 81  ? 64.74383 -0.84523  33.69982  1.000 14.33790 ? 81  ASN C C   1 
ATOM   2846 O O   . ASN C 1 81  ? 64.76229 0.30664   33.26279  1.000 16.62788 ? 81  ASN C O   1 
ATOM   2847 C CB  . ASN C 1 81  ? 65.07114 -2.32331  31.71227  1.000 14.13533 ? 81  ASN C CB  1 
ATOM   2848 C CG  . ASN C 1 81  ? 64.76708 -3.69100  31.12877  1.000 15.57136 ? 81  ASN C CG  1 
ATOM   2849 O OD1 . ASN C 1 81  ? 64.50502 -4.63600  31.86427  1.000 18.24229 ? 81  ASN C OD1 1 
ATOM   2850 N ND2 . ASN C 1 81  ? 64.79448 -3.79872  29.81023  1.000 17.64766 ? 81  ASN C ND2 1 
ATOM   2851 N N   . HIS C 1 82  ? 65.27223 -1.17766  34.87708  1.000 15.81638 ? 82  HIS C N   1 
ATOM   2852 C CA  . HIS C 1 82  ? 65.92458 -0.18357  35.72074  1.000 16.63295 ? 82  HIS C CA  1 
ATOM   2853 C C   . HIS C 1 82  ? 66.85379 -0.90374  36.68409  1.000 18.52818 ? 82  HIS C C   1 
ATOM   2854 O O   . HIS C 1 82  ? 66.63247 -2.06929  37.02172  1.000 17.90013 ? 82  HIS C O   1 
ATOM   2855 C CB  . HIS C 1 82  ? 64.89377 0.70214   36.44849  1.000 15.95935 ? 82  HIS C CB  1 
ATOM   2856 C CG  . HIS C 1 82  ? 64.02336 -0.03007  37.42120  1.000 17.14878 ? 82  HIS C CG  1 
ATOM   2857 N ND1 . HIS C 1 82  ? 64.17515 0.07226   38.78778  1.000 17.02615 ? 82  HIS C ND1 1 
ATOM   2858 C CD2 . HIS C 1 82  ? 62.99002 -0.88851  37.22194  1.000 15.16487 ? 82  HIS C CD2 1 
ATOM   2859 C CE1 . HIS C 1 82  ? 63.26801 -0.67825  39.38729  1.000 16.72606 ? 82  HIS C CE1 1 
ATOM   2860 N NE2 . HIS C 1 82  ? 62.53670 -1.27283  38.45982  1.000 15.87050 ? 82  HIS C NE2 1 
ATOM   2861 N N   . SER C 1 83  ? 67.91122 -0.21020  37.10508  1.000 18.03969 ? 83  SER C N   1 
ATOM   2862 C CA  . SER C 1 83  ? 68.90684 -0.81049  38.00284  1.000 18.05036 ? 83  SER C CA  1 
ATOM   2863 C C   . SER C 1 83  ? 69.36131 -2.13564  37.38726  1.000 19.64412 ? 83  SER C C   1 
ATOM   2864 O O   . SER C 1 83  ? 69.58944 -2.18566  36.16939  1.000 18.71781 ? 83  SER C O   1 
ATOM   2865 C CB  . SER C 1 83  ? 68.34637 -0.87164  39.42305  1.000 20.73914 ? 83  SER C CB  1 
ATOM   2866 O OG  . SER C 1 83  ? 69.21494 -1.57139  40.30450  1.000 24.32164 ? 83  SER C OG  1 
ATOM   2867 N N   . THR C 1 84  ? 69.48201 -3.21225  38.16262  1.000 19.44874 ? 84  THR C N   1 
ATOM   2868 C CA  . THR C 1 84  ? 69.96790 -4.49282  37.67836  1.000 20.67931 ? 84  THR C CA  1 
ATOM   2869 C C   . THR C 1 84  ? 68.86046 -5.39455  37.15486  1.000 19.60730 ? 84  THR C C   1 
ATOM   2870 O O   . THR C 1 84  ? 69.15590 -6.49903  36.68625  1.000 18.97816 ? 84  THR C O   1 
ATOM   2871 C CB  . THR C 1 84  ? 70.71476 -5.22310  38.80054  1.000 20.30579 ? 84  THR C CB  1 
ATOM   2872 O OG1 . THR C 1 84  ? 69.92149 -5.21399  39.99342  1.000 22.89815 ? 84  THR C OG1 1 
ATOM   2873 C CG2 . THR C 1 84  ? 72.04500 -4.54886  39.08845  1.000 23.10231 ? 84  THR C CG2 1 
ATOM   2874 N N   . GLY C 1 85  ? 67.60201 -4.94913  37.19618  1.000 17.68130 ? 85  GLY C N   1 
ATOM   2875 C CA  . GLY C 1 85  ? 66.50342 -5.79801  36.77341  1.000 19.31483 ? 85  GLY C CA  1 
ATOM   2876 C C   . GLY C 1 85  ? 65.37684 -5.06137  36.08323  1.000 15.65805 ? 85  GLY C C   1 
ATOM   2877 O O   . GLY C 1 85  ? 65.60613 -4.22207  35.20448  1.000 14.95859 ? 85  GLY C O   1 
ATOM   2878 N N   . CYS C 1 86  ? 64.14405 -5.37210  36.47357  1.000 13.99335 ? 86  CYS C N   1 
ATOM   2879 C CA  . CYS C 1 86  ? 63.00562 -4.74381  35.82165  1.000 15.08649 ? 86  CYS C CA  1 
ATOM   2880 C C   . CYS C 1 86  ? 61.78434 -4.83919  36.72226  1.000 16.47620 ? 86  CYS C C   1 
ATOM   2881 O O   . CYS C 1 86  ? 61.70876 -5.67107  37.63474  1.000 16.11669 ? 86  CYS C O   1 
ATOM   2882 C CB  . CYS C 1 86  ? 62.73984 -5.35114  34.44005  1.000 17.50014 ? 86  CYS C CB  1 
ATOM   2883 S SG  . CYS C 1 86  ? 61.88113 -6.94275  34.42324  0.861 18.68871 ? 86  CYS C SG  1 
ATOM   2884 N N   . THR C 1 87  ? 60.82670 -3.96495  36.44635  1.000 14.67231 ? 87  THR C N   1 
ATOM   2885 C CA  . THR C 1 87  ? 59.55421 -3.95248  37.14310  1.000 15.54205 ? 87  THR C CA  1 
ATOM   2886 C C   . THR C 1 87  ? 58.46216 -3.83485  36.09989  1.000 15.93093 ? 87  THR C C   1 
ATOM   2887 O O   . THR C 1 87  ? 58.62810 -3.13387  35.09353  1.000 15.51125 ? 87  THR C O   1 
ATOM   2888 C CB  . THR C 1 87  ? 59.49200 -2.77395  38.11653  1.000 16.16407 ? 87  THR C CB  1 
ATOM   2889 O OG1 . THR C 1 87  ? 60.50872 -2.93861  39.11968  1.000 17.04725 ? 87  THR C OG1 1 
ATOM   2890 C CG2 . THR C 1 87  ? 58.13488 -2.68960  38.79168  1.000 18.84862 ? 87  THR C CG2 1 
ATOM   2891 N N   . ALA C 1 88  ? 57.35551 -4.53118  36.33784  1.000 14.81487 ? 88  ALA C N   1 
ATOM   2892 C CA  . ALA C 1 88  ? 56.26261 -4.60678  35.38752  1.000 14.97639 ? 88  ALA C CA  1 
ATOM   2893 C C   . ALA C 1 88  ? 54.97610 -4.11703  36.03412  1.000 14.75931 ? 88  ALA C C   1 
ATOM   2894 O O   . ALA C 1 88  ? 54.75115 -4.30797  37.23595  1.000 14.76139 ? 88  ALA C O   1 
ATOM   2895 C CB  . ALA C 1 88  ? 56.07319 -6.04169  34.93825  1.000 17.09402 ? 88  ALA C CB  1 
ATOM   2896 N N   . TYR C 1 89  ? 54.13816 -3.48082  35.21742  1.000 12.37887 ? 89  TYR C N   1 
ATOM   2897 C CA  . TYR C 1 89  ? 52.80692 -3.02850  35.60646  1.000 12.46421 ? 89  TYR C CA  1 
ATOM   2898 C C   . TYR C 1 89  ? 51.79178 -3.95286  34.94401  1.000 13.64520 ? 89  TYR C C   1 
ATOM   2899 O O   . TYR C 1 89  ? 51.84370 -4.16140  33.72692  1.000 13.62446 ? 89  TYR C O   1 
ATOM   2900 C CB  . TYR C 1 89  ? 52.60016 -1.57476  35.15550  1.000 13.55134 ? 89  TYR C CB  1 
ATOM   2901 C CG  . TYR C 1 89  ? 53.62075 -0.60349  35.72386  1.000 11.27184 ? 89  TYR C CG  1 
ATOM   2902 C CD1 . TYR C 1 89  ? 53.38083 0.06820   36.92870  1.000 13.09644 ? 89  TYR C CD1 1 
ATOM   2903 C CD2 . TYR C 1 89  ? 54.83470 -0.38653  35.07794  1.000 13.23250 ? 89  TYR C CD2 1 
ATOM   2904 C CE1 . TYR C 1 89  ? 54.31584 0.93809   37.45399  1.000 13.05335 ? 89  TYR C CE1 1 
ATOM   2905 C CE2 . TYR C 1 89  ? 55.75974 0.49317   35.58404  1.000 13.96718 ? 89  TYR C CE2 1 
ATOM   2906 C CZ  . TYR C 1 89  ? 55.50511 1.14770   36.77415  1.000 13.69234 ? 89  TYR C CZ  1 
ATOM   2907 O OH  . TYR C 1 89  ? 56.46583 2.00168   37.27610  1.000 13.72248 ? 89  TYR C OH  1 
ATOM   2908 N N   . VAL C 1 90  ? 50.87861 -4.52404  35.74331  1.000 13.00602 ? 90  VAL C N   1 
ATOM   2909 C CA  . VAL C 1 90  ? 50.03494 -5.64154  35.32110  1.000 13.83336 ? 90  VAL C CA  1 
ATOM   2910 C C   . VAL C 1 90  ? 48.58959 -5.17529  35.20668  1.000 12.84570 ? 90  VAL C C   1 
ATOM   2911 O O   . VAL C 1 90  ? 48.08026 -4.46795  36.08651  1.000 15.23504 ? 90  VAL C O   1 
ATOM   2912 C CB  . VAL C 1 90  ? 50.12500 -6.79738  36.33700  1.000 14.23373 ? 90  VAL C CB  1 
ATOM   2913 C CG1 . VAL C 1 90  ? 49.18263 -7.93494  35.96138  1.000 14.30481 ? 90  VAL C CG1 1 
ATOM   2914 C CG2 . VAL C 1 90  ? 51.55603 -7.28568  36.48028  1.000 13.44837 ? 90  VAL C CG2 1 
ATOM   2915 N N   . TYR C 1 91  ? 47.91969 -5.61078  34.13809  1.000 13.14211 ? 91  TYR C N   1 
ATOM   2916 C CA  . TYR C 1 91  ? 46.49013 -5.37232  33.94382  1.000 13.25307 ? 91  TYR C CA  1 
ATOM   2917 C C   . TYR C 1 91  ? 45.79657 -6.67452  33.57188  1.000 15.04172 ? 91  TYR C C   1 
ATOM   2918 O O   . TYR C 1 91  ? 46.20002 -7.35185  32.62185  1.000 15.25326 ? 91  TYR C O   1 
ATOM   2919 C CB  . TYR C 1 91  ? 46.22632 -4.29952  32.86164  1.000 12.12806 ? 91  TYR C CB  1 
ATOM   2920 C CG  . TYR C 1 91  ? 46.79111 -2.95816  33.24484  1.000 13.63737 ? 91  TYR C CG  1 
ATOM   2921 C CD1 . TYR C 1 91  ? 48.15149 -2.69011  33.07108  1.000 14.77510 ? 91  TYR C CD1 1 
ATOM   2922 C CD2 . TYR C 1 91  ? 45.98263 -1.97096  33.81048  1.000 15.65257 ? 91  TYR C CD2 1 
ATOM   2923 C CE1 . TYR C 1 91  ? 48.68470 -1.46190  33.44219  1.000 15.11632 ? 91  TYR C CE1 1 
ATOM   2924 C CE2 . TYR C 1 91  ? 46.50428 -0.74952  34.18263  1.000 14.79873 ? 91  TYR C CE2 1 
ATOM   2925 C CZ  . TYR C 1 91  ? 47.84720 -0.49916  33.99387  1.000 15.71209 ? 91  TYR C CZ  1 
ATOM   2926 O OH  . TYR C 1 91  ? 48.34862 0.72495   34.37102  1.000 16.24688 ? 91  TYR C OH  1 
ATOM   2927 N N   . GLY C 1 92  ? 44.73623 -7.01468  34.30590  1.000 14.87989 ? 92  GLY C N   1 
ATOM   2928 C CA  . GLY C 1 92  ? 43.95219 -8.18679  33.95905  1.000 14.40944 ? 92  GLY C CA  1 
ATOM   2929 C C   . GLY C 1 92  ? 43.14566 -7.96501  32.69262  1.000 13.08333 ? 92  GLY C C   1 
ATOM   2930 O O   . GLY C 1 92  ? 42.78762 -6.84289  32.34384  1.000 13.74927 ? 92  GLY C O   1 
ATOM   2931 N N   . ARG C 1 93  ? 42.86898 -9.06097  31.98245  1.000 13.83280 ? 93  ARG C N   1 
ATOM   2932 C CA  . ARG C 1 93  ? 42.01048 -9.02098  30.80711  1.000 15.03317 ? 93  ARG C CA  1 
ATOM   2933 C C   . ARG C 1 93  ? 40.95167 -10.10990 30.87723  1.000 15.19139 ? 93  ARG C C   1 
ATOM   2934 O O   . ARG C 1 93  ? 41.15118 -11.15413 31.49836  1.000 15.37778 ? 93  ARG C O   1 
ATOM   2935 C CB  . ARG C 1 93  ? 42.80500 -9.19367  29.50705  1.000 16.25887 ? 93  ARG C CB  1 
ATOM   2936 C CG  . ARG C 1 93  ? 43.99157 -8.24208  29.37902  1.000 16.14817 ? 93  ARG C CG  1 
ATOM   2937 C CD  . ARG C 1 93  ? 44.64375 -8.33530  28.00555  1.000 16.90482 ? 93  ARG C CD  1 
ATOM   2938 N NE  . ARG C 1 93  ? 43.95515 -7.55820  26.97289  1.000 17.57882 ? 93  ARG C NE  1 
ATOM   2939 C CZ  . ARG C 1 93  ? 43.64901 -8.03240  25.76966  1.000 19.29759 ? 93  ARG C CZ  1 
ATOM   2940 N NH1 . ARG C 1 93  ? 43.96219 -9.28005  25.45129  1.000 21.75724 ? 93  ARG C NH1 1 
ATOM   2941 N NH2 . ARG C 1 93  ? 43.02965 -7.27029  24.88087  1.000 19.99083 ? 93  ARG C NH2 1 
ATOM   2942 N N   . GLY C 1 94  ? 39.81483 -9.84746  30.23903  1.000 16.05591 ? 94  GLY C N   1 
ATOM   2943 C CA  . GLY C 1 94  ? 38.81328 -10.88011 30.09128  1.000 15.80939 ? 94  GLY C CA  1 
ATOM   2944 C C   . GLY C 1 94  ? 38.11201 -11.27132 31.36677  1.000 16.68586 ? 94  GLY C C   1 
ATOM   2945 O O   . GLY C 1 94  ? 37.42851 -12.30373 31.39065  1.000 17.86354 ? 94  GLY C O   1 
ATOM   2946 N N   . GLY C 1 95  ? 38.25338 -10.48293 32.43012  1.000 15.53657 ? 95  GLY C N   1 
ATOM   2947 C CA  . GLY C 1 95  ? 37.73410 -10.83627 33.73030  1.000 16.21833 ? 95  GLY C CA  1 
ATOM   2948 C C   . GLY C 1 95  ? 38.75310 -11.44120 34.66712  1.000 15.82172 ? 95  GLY C C   1 
ATOM   2949 O O   . GLY C 1 95  ? 38.46136 -11.59780 35.86081  1.000 19.19457 ? 95  GLY C O   1 
ATOM   2950 N N   . TYR C 1 96  ? 39.94305 -11.76494 34.17055  1.000 16.28967 ? 96  TYR C N   1 
ATOM   2951 C CA  . TYR C 1 96  ? 40.94576 -12.44006 34.97869  1.000 18.27381 ? 96  TYR C CA  1 
ATOM   2952 C C   . TYR C 1 96  ? 41.85103 -11.43501 35.68545  1.000 16.10106 ? 96  TYR C C   1 
ATOM   2953 O O   . TYR C 1 96  ? 41.84825 -10.23477 35.38696  1.000 14.78570 ? 96  TYR C O   1 
ATOM   2954 C CB  . TYR C 1 96  ? 41.75537 -13.40995 34.11132  1.000 17.90975 ? 96  TYR C CB  1 
ATOM   2955 C CG  . TYR C 1 96  ? 40.85700 -14.44265 33.47578  1.000 22.75929 ? 96  TYR C CG  1 
ATOM   2956 C CD1 . TYR C 1 96  ? 40.57742 -15.63047 34.12476  1.000 25.43729 ? 96  TYR C CD1 1 
ATOM   2957 C CD2 . TYR C 1 96  ? 40.27624 -14.21739 32.22748  1.000 22.06941 ? 96  TYR C CD2 1 
ATOM   2958 C CE1 . TYR C 1 96  ? 39.72559 -16.57899 33.55794  1.000 24.84177 ? 96  TYR C CE1 1 
ATOM   2959 C CE2 . TYR C 1 96  ? 39.43125 -15.16331 31.64673  1.000 24.71755 ? 96  TYR C CE2 1 
ATOM   2960 C CZ  . TYR C 1 96  ? 39.16597 -16.33835 32.32399  1.000 27.17348 ? 96  TYR C CZ  1 
ATOM   2961 O OH  . TYR C 1 96  ? 38.33529 -17.27917 31.76100  1.000 33.32554 ? 96  TYR C OH  1 
ATOM   2962 N N   . TYR C 1 97  ? 42.60511 -11.94336 36.66659  1.000 14.52453 ? 97  TYR C N   1 
ATOM   2963 C CA  . TYR C 1 97  ? 43.66087 -11.19387 37.33704  1.000 15.39875 ? 97  TYR C CA  1 
ATOM   2964 C C   . TYR C 1 97  ? 44.82325 -12.14297 37.57554  1.000 16.75735 ? 97  TYR C C   1 
ATOM   2965 O O   . TYR C 1 97  ? 44.69031 -13.36555 37.43376  1.000 15.78420 ? 97  TYR C O   1 
ATOM   2966 C CB  . TYR C 1 97  ? 43.17416 -10.55948 38.64933  1.000 16.43706 ? 97  TYR C CB  1 
ATOM   2967 C CG  . TYR C 1 97  ? 42.81167 -11.54835 39.73926  1.000 17.23876 ? 97  TYR C CG  1 
ATOM   2968 C CD1 . TYR C 1 97  ? 43.77395 -12.01028 40.63631  1.000 16.95966 ? 97  TYR C CD1 1 
ATOM   2969 C CD2 . TYR C 1 97  ? 41.50232 -12.00945 39.87777  1.000 16.19221 ? 97  TYR C CD2 1 
ATOM   2970 C CE1 . TYR C 1 97  ? 43.44401 -12.91902 41.63910  1.000 16.44939 ? 97  TYR C CE1 1 
ATOM   2971 C CE2 . TYR C 1 97  ? 41.16641 -12.91368 40.87730  1.000 18.20530 ? 97  TYR C CE2 1 
ATOM   2972 C CZ  . TYR C 1 97  ? 42.13998 -13.35692 41.75537  1.000 17.41090 ? 97  TYR C CZ  1 
ATOM   2973 O OH  . TYR C 1 97  ? 41.82259 -14.25428 42.74869  1.000 20.83083 ? 97  TYR C OH  1 
ATOM   2974 N N   . LEU C 1 98  ? 45.98124 -11.58350 37.93612  1.000 14.17901 ? 98  LEU C N   1 
ATOM   2975 C CA  . LEU C 1 98  ? 47.13855 -12.44007 38.18689  1.000 18.48304 ? 98  LEU C CA  1 
ATOM   2976 C C   . LEU C 1 98  ? 47.29995 -12.77786 39.66074  1.000 17.89439 ? 98  LEU C C   1 
ATOM   2977 O O   . LEU C 1 98  ? 47.29836 -11.88845 40.51954  1.000 16.81874 ? 98  LEU C O   1 
ATOM   2978 C CB  . LEU C 1 98  ? 48.47984 -11.93812 37.64742  1.000 22.54696 ? 98  LEU C CB  1 
ATOM   2979 C CG  . LEU C 1 98  ? 48.63844 -11.84165 36.13916  1.000 23.55548 ? 98  LEU C CG  1 
ATOM   2980 C CD1 . LEU C 1 98  ? 49.99113 -11.25081 35.76116  1.000 25.30239 ? 98  LEU C CD1 1 
ATOM   2981 C CD2 . LEU C 1 98  ? 48.34731 -13.13837 35.48941  1.000 22.11955 ? 98  LEU C CD2 1 
ATOM   2982 N N   . SER C 1 99  ? 47.46684 -14.06854 39.93522  1.000 17.87183 ? 99  SER C N   1 
ATOM   2983 C CA  . SER C 1 99  ? 47.92826 -14.50763 41.23837  1.000 18.32994 ? 99  SER C CA  1 
ATOM   2984 C C   . SER C 1 99  ? 49.22486 -13.80898 41.60640  1.000 17.86844 ? 99  SER C C   1 
ATOM   2985 O O   . SER C 1 99  ? 50.10665 -13.60118 40.76724  1.000 18.23494 ? 99  SER C O   1 
ATOM   2986 C CB  . SER C 1 99  ? 48.18377 -16.01236 41.21010  1.000 19.27577 ? 99  SER C CB  1 
ATOM   2987 O OG  . SER C 1 99  ? 48.77013 -16.42162 42.42709  1.000 21.24185 ? 99  SER C OG  1 
ATOM   2988 N N   . MET C 1 100 ? 49.33759 -13.45790 42.87904  1.000 17.41049 ? 100 MET C N   1 
ATOM   2989 C CA  . MET C 1 100 ? 50.52417 -12.82823 43.44434  1.000 21.10306 ? 100 MET C CA  1 
ATOM   2990 C C   . MET C 1 100 ? 51.37718 -13.75313 44.31478  1.000 20.38131 ? 100 MET C C   1 
ATOM   2991 O O   . MET C 1 100 ? 52.31857 -13.28239 44.95933  1.000 21.87319 ? 100 MET C O   1 
ATOM   2992 C CB  . MET C 1 100 ? 50.14400 -11.51851 44.14303  1.000 22.21543 ? 100 MET C CB  1 
ATOM   2993 C CG  . MET C 1 100 ? 48.99753 -11.70822 45.12536  1.000 24.88151 ? 100 MET C CG  1 
ATOM   2994 S SD  . MET C 1 100 ? 49.29490 -12.67069 46.60846  0.746 22.76752 ? 100 MET C SD  1 
ATOM   2995 C CE  . MET C 1 100 ? 50.66407 -11.79935 47.34828  1.000 28.80971 ? 100 MET C CE  1 
ATOM   2996 N N   . TYR C 1 101 ? 51.09690 -15.05469 44.30941  1.000 21.73493 ? 101 TYR C N   1 
ATOM   2997 C CA  . TYR C 1 101 ? 51.81428 -16.00526 45.15182  1.000 24.45946 ? 101 TYR C CA  1 
ATOM   2998 C C   . TYR C 1 101 ? 53.26645 -16.18176 44.69511  1.000 25.97540 ? 101 TYR C C   1 
ATOM   2999 O O   . TYR C 1 101 ? 53.62674 -15.92906 43.54166  1.000 23.66882 ? 101 TYR C O   1 
ATOM   3000 C CB  . TYR C 1 101 ? 51.09008 -17.35272 45.16875  1.000 26.01727 ? 101 TYR C CB  1 
ATOM   3001 N N   . LYS C 1 102 ? 54.08742 -16.67766 45.62811  1.000 26.40964 ? 102 LYS C N   1 
ATOM   3002 C CA  . LYS C 1 102 ? 55.54708 -16.65904 45.49741  1.000 26.83289 ? 102 LYS C CA  1 
ATOM   3003 C C   . LYS C 1 102 ? 56.05628 -17.27247 44.19361  1.000 30.22119 ? 102 LYS C C   1 
ATOM   3004 O O   . LYS C 1 102 ? 56.99297 -16.74513 43.58109  1.000 30.41032 ? 102 LYS C O   1 
ATOM   3005 C CB  . LYS C 1 102 ? 56.18467 -17.36521 46.69716  1.000 28.78969 ? 102 LYS C CB  1 
ATOM   3006 N N   . GLY C 1 103 ? 55.49639 -18.39859 43.77066  1.000 28.26368 ? 103 GLY C N   1 
ATOM   3007 C CA  . GLY C 1 103 ? 55.97689 -19.06769 42.57635  1.000 26.53564 ? 103 GLY C CA  1 
ATOM   3008 C C   . GLY C 1 103 ? 55.16264 -18.84366 41.31995  1.000 24.64996 ? 103 GLY C C   1 
ATOM   3009 O O   . GLY C 1 103 ? 55.37845 -19.54707 40.32568  1.000 26.92769 ? 103 GLY C O   1 
ATOM   3010 N N   . ASP C 1 104 ? 54.24222 -17.87961 41.31931  1.000 23.99440 ? 104 ASP C N   1 
ATOM   3011 C CA  . ASP C 1 104 ? 53.23536 -17.77919 40.27063  1.000 23.35227 ? 104 ASP C CA  1 
ATOM   3012 C C   . ASP C 1 104 ? 53.52549 -16.71628 39.21087  1.000 19.61435 ? 104 ASP C C   1 
ATOM   3013 O O   . ASP C 1 104 ? 52.67963 -16.49925 38.33504  1.000 23.49806 ? 104 ASP C O   1 
ATOM   3014 C CB  . ASP C 1 104 ? 51.85169 -17.52820 40.88278  1.000 21.84244 ? 104 ASP C CB  1 
ATOM   3015 C CG  . ASP C 1 104 ? 51.26961 -18.75962 41.56643  1.000 24.01912 ? 104 ASP C CG  1 
ATOM   3016 O OD1 . ASP C 1 104 ? 51.80783 -19.87874 41.38933  1.000 24.70616 ? 104 ASP C OD1 1 
ATOM   3017 O OD2 . ASP C 1 104 ? 50.25243 -18.60143 42.27320  1.000 24.22868 ? 104 ASP C OD2 1 
ATOM   3018 N N   . VAL C 1 105 ? 54.66653 -16.03239 39.25986  1.000 19.34626 ? 105 VAL C N   1 
ATOM   3019 C CA  . VAL C 1 105 ? 54.97752 -15.02820 38.23696  1.000 18.09930 ? 105 VAL C CA  1 
ATOM   3020 C C   . VAL C 1 105 ? 56.46460 -15.16046 37.92143  1.000 19.52357 ? 105 VAL C C   1 
ATOM   3021 O O   . VAL C 1 105 ? 57.30839 -14.77304 38.73783  1.000 21.84250 ? 105 VAL C O   1 
ATOM   3022 C CB  . VAL C 1 105 ? 54.66016 -13.58761 38.68426  1.000 18.57760 ? 105 VAL C CB  1 
ATOM   3023 C CG1 . VAL C 1 105 ? 54.79302 -12.63762 37.50718  1.000 18.34286 ? 105 VAL C CG1 1 
ATOM   3024 C CG2 . VAL C 1 105 ? 53.27718 -13.45743 39.33357  1.000 20.48830 ? 105 VAL C CG2 1 
ATOM   3025 N N   . LYS C 1 106 ? 56.79129 -15.66115 36.73305  1.000 17.43587 ? 106 LYS C N   1 
ATOM   3026 C CA  . LYS C 1 106 ? 58.18580 -15.84459 36.34197  1.000 15.01071 ? 106 LYS C CA  1 
ATOM   3027 C C   . LYS C 1 106 ? 58.51946 -15.06336 35.07971  1.000 15.03698 ? 106 LYS C C   1 
ATOM   3028 O O   . LYS C 1 106 ? 57.71273 -14.98306 34.15751  1.000 16.38560 ? 106 LYS C O   1 
ATOM   3029 C CB  . LYS C 1 106 ? 58.49705 -17.31698 36.09020  1.000 19.01295 ? 106 LYS C CB  1 
ATOM   3030 C CG  . LYS C 1 106 ? 58.38906 -18.18086 37.31612  1.000 19.39205 ? 106 LYS C CG  1 
ATOM   3031 C CD  . LYS C 1 106 ? 58.77670 -19.61801 36.96515  1.000 23.73009 ? 106 LYS C CD  1 
ATOM   3032 C CE  . LYS C 1 106 ? 58.07318 -20.59711 37.87068  1.000 31.10491 ? 106 LYS C CE  1 
ATOM   3033 N NZ  . LYS C 1 106 ? 58.73581 -20.62010 39.19074  1.000 30.68113 ? 106 LYS C NZ  1 
ATOM   3034 N N   . LEU C 1 107 ? 59.73138 -14.51509 35.03465  1.000 15.30719 ? 107 LEU C N   1 
ATOM   3035 C CA  . LEU C 1 107 ? 60.26866 -13.87952 33.84040  1.000 14.96449 ? 107 LEU C CA  1 
ATOM   3036 C C   . LEU C 1 107 ? 61.53259 -14.64365 33.46269  1.000 15.06957 ? 107 LEU C C   1 
ATOM   3037 O O   . LEU C 1 107 ? 62.45824 -14.75180 34.27600  1.000 14.81297 ? 107 LEU C O   1 
ATOM   3038 C CB  . LEU C 1 107 ? 60.57754 -12.39825 34.09678  1.000 14.89473 ? 107 LEU C CB  1 
ATOM   3039 C CG  . LEU C 1 107 ? 61.09738 -11.58751 32.90745  1.000 15.13652 ? 107 LEU C CG  1 
ATOM   3040 C CD1 . LEU C 1 107 ? 60.10383 -11.54092 31.75531  1.000 14.44812 ? 107 LEU C CD1 1 
ATOM   3041 C CD2 . LEU C 1 107 ? 61.48842 -10.17746 33.33189  1.000 15.22659 ? 107 LEU C CD2 1 
ATOM   3042 N N   . ASN C 1 108 ? 61.55762 -15.20538 32.25173  1.000 16.01575 ? 108 ASN C N   1 
ATOM   3043 C CA  . ASN C 1 108 ? 62.69034 -16.03996 31.82507  1.000 15.55139 ? 108 ASN C CA  1 
ATOM   3044 C C   . ASN C 1 108 ? 62.92484 -17.18304 32.81451  1.000 19.47187 ? 108 ASN C C   1 
ATOM   3045 O O   . ASN C 1 108 ? 64.06541 -17.55775 33.10695  1.000 18.30472 ? 108 ASN C O   1 
ATOM   3046 C CB  . ASN C 1 108 ? 63.96515 -15.20740 31.60655  1.000 17.20388 ? 108 ASN C CB  1 
ATOM   3047 C CG  . ASN C 1 108 ? 64.97179 -15.90460 30.70745  1.000 21.43390 ? 108 ASN C CG  1 
ATOM   3048 O OD1 . ASN C 1 108 ? 64.60697 -16.74822 29.88759  1.000 22.28310 ? 108 ASN C OD1 1 
ATOM   3049 N ND2 . ASN C 1 108 ? 66.24366 -15.55487 30.85642  1.000 25.61528 ? 108 ASN C ND2 1 
ATOM   3050 N N   . SER C 1 109 ? 61.83031 -17.72030 33.35172  1.000 15.83520 ? 109 SER C N   1 
ATOM   3051 C CA  . SER C 1 109 ? 61.79992 -18.80191 34.33178  1.000 15.60530 ? 109 SER C CA  1 
ATOM   3052 C C   . SER C 1 109 ? 62.35626 -18.40627 35.69628  1.000 17.20491 ? 109 SER C C   1 
ATOM   3053 O O   . SER C 1 109 ? 62.61356 -19.28712 36.52389  1.000 19.24017 ? 109 SER C O   1 
ATOM   3054 C CB  . SER C 1 109 ? 62.42751 -20.10090 33.79727  1.000 19.44809 ? 109 SER C CB  1 
ATOM   3055 O OG  . SER C 1 109 ? 61.52869 -20.74365 32.89426  1.000 24.66389 ? 109 SER C OG  1 
ATOM   3056 N N   . VAL C 1 110 ? 62.53467 -17.10467 35.96363  1.000 14.66810 ? 110 VAL C N   1 
ATOM   3057 C CA  . VAL C 1 110 ? 63.02740 -16.60230 37.24796  1.000 16.08412 ? 110 VAL C CA  1 
ATOM   3058 C C   . VAL C 1 110 ? 61.84716 -16.07578 38.05466  1.000 18.01878 ? 110 VAL C C   1 
ATOM   3059 O O   . VAL C 1 110 ? 61.05228 -15.27525 37.54910  1.000 16.75142 ? 110 VAL C O   1 
ATOM   3060 C CB  . VAL C 1 110 ? 64.06565 -15.48334 37.03913  1.000 18.29544 ? 110 VAL C CB  1 
ATOM   3061 C CG1 . VAL C 1 110 ? 64.54836 -14.96144 38.37868  1.000 16.23244 ? 110 VAL C CG1 1 
ATOM   3062 C CG2 . VAL C 1 110 ? 65.22768 -15.96581 36.16064  1.000 17.38089 ? 110 VAL C CG2 1 
ATOM   3063 N N   . ASP C 1 111 ? 61.73337 -16.50336 39.31410  1.000 18.81102 ? 111 ASP C N   1 
ATOM   3064 C CA  . ASP C 1 111 ? 60.66211 -16.01654 40.17546  1.000 19.36718 ? 111 ASP C CA  1 
ATOM   3065 C C   . ASP C 1 111 ? 60.87965 -14.55090 40.53683  1.000 18.41951 ? 111 ASP C C   1 
ATOM   3066 O O   . ASP C 1 111 ? 62.01131 -14.08411 40.68848  1.000 16.73431 ? 111 ASP C O   1 
ATOM   3067 C CB  . ASP C 1 111 ? 60.61520 -16.79893 41.48839  1.000 21.10000 ? 111 ASP C CB  1 
ATOM   3068 C CG  . ASP C 1 111 ? 60.08715 -18.20408 41.32046  1.000 23.77998 ? 111 ASP C CG  1 
ATOM   3069 O OD1 . ASP C 1 111 ? 59.05588 -18.39684 40.65011  1.000 22.41593 ? 111 ASP C OD1 1 
ATOM   3070 O OD2 . ASP C 1 111 ? 60.70517 -19.12256 41.89641  1.000 30.01930 ? 111 ASP C OD2 1 
ATOM   3071 N N   . HIS C 1 112 ? 59.77384 -13.82923 40.70319  1.000 20.36917 ? 112 HIS C N   1 
ATOM   3072 C CA  . HIS C 1 112 ? 59.85004 -12.42753 41.08745  1.000 19.62923 ? 112 HIS C CA  1 
ATOM   3073 C C   . HIS C 1 112 ? 60.36172 -12.27685 42.51922  1.000 20.47476 ? 112 HIS C C   1 
ATOM   3074 O O   . HIS C 1 112 ? 60.33781 -13.21690 43.32288  1.000 21.71256 ? 112 HIS C O   1 
ATOM   3075 C CB  . HIS C 1 112 ? 58.46805 -11.78834 41.01309  1.000 18.10913 ? 112 HIS C CB  1 
ATOM   3076 C CG  . HIS C 1 112 ? 57.48982 -12.36483 41.98475  1.000 20.74064 ? 112 HIS C CG  1 
ATOM   3077 N ND1 . HIS C 1 112 ? 56.69366 -13.44870 41.68583  1.000 24.85583 ? 112 HIS C ND1 1 
ATOM   3078 C CD2 . HIS C 1 112 ? 57.18235 -12.01231 43.25458  1.000 22.23710 ? 112 HIS C CD2 1 
ATOM   3079 C CE1 . HIS C 1 112 ? 55.93843 -13.74070 42.72965  1.000 22.99052 ? 112 HIS C CE1 1 
ATOM   3080 N NE2 . HIS C 1 112 ? 56.20815 -12.87745 43.69101  1.000 22.77728 ? 112 HIS C NE2 1 
ATOM   3081 N N   . ASN C 1 113 ? 60.82221 -11.06019 42.82967  1.000 19.24268 ? 113 ASN C N   1 
ATOM   3082 C CA  . ASN C 1 113 ? 61.27428 -10.67479 44.16474  1.000 22.33913 ? 113 ASN C CA  1 
ATOM   3083 C C   . ASN C 1 113 ? 60.23081 -9.93105  44.98623  1.000 23.19203 ? 113 ASN C C   1 
ATOM   3084 O O   . ASN C 1 113 ? 60.10613 -10.19451 46.18369  1.000 26.19866 ? 113 ASN C O   1 
ATOM   3085 C CB  . ASN C 1 113 ? 62.53153 -9.79987  44.09244  1.000 22.76960 ? 113 ASN C CB  1 
ATOM   3086 C CG  . ASN C 1 113 ? 63.73406 -10.54585 43.56944  1.000 27.70550 ? 113 ASN C CG  1 
ATOM   3087 O OD1 . ASN C 1 113 ? 63.97914 -10.59709 42.36320  1.000 19.70888 ? 113 ASN C OD1 1 
ATOM   3088 N ND2 . ASN C 1 113 ? 64.48928 -11.15153 44.48222  1.000 29.17291 ? 113 ASN C ND2 1 
ATOM   3089 N N   . GLU C 1 114 ? 59.52270 -8.96529  44.40076  1.000 23.09965 ? 114 GLU C N   1 
ATOM   3090 C CA  . GLU C 1 114 ? 58.53145 -8.16628  45.11579  1.000 21.65310 ? 114 GLU C CA  1 
ATOM   3091 C C   . GLU C 1 114 ? 57.29376 -8.01466  44.24355  1.000 21.38371 ? 114 GLU C C   1 
ATOM   3092 O O   . GLU C 1 114 ? 57.39062 -7.98031  43.01180  1.000 22.91727 ? 114 GLU C O   1 
ATOM   3093 C CB  . GLU C 1 114 ? 59.03896 -6.74656  45.43553  1.000 21.19436 ? 114 GLU C CB  1 
ATOM   3094 C CG  . GLU C 1 114 ? 60.22511 -6.67893  46.39815  1.000 29.21547 ? 114 GLU C CG  1 
ATOM   3095 C CD  . GLU C 1 114 ? 59.89565 -7.20635  47.78559  1.000 28.62243 ? 114 GLU C CD  1 
ATOM   3096 O OE1 . GLU C 1 114 ? 58.70279 -7.23425  48.15723  1.000 36.03194 ? 114 GLU C OE1 1 
ATOM   3097 O OE2 . GLU C 1 114 ? 60.83878 -7.59559  48.50376  1.000 34.65403 ? 114 GLU C OE2 1 
ATOM   3098 N N   . ILE C 1 115 ? 56.13029 -7.92650  44.89596  1.000 22.15562 ? 115 ILE C N   1 
ATOM   3099 C CA  . ILE C 1 115 ? 54.84805 -7.65747  44.24519  1.000 18.99420 ? 115 ILE C CA  1 
ATOM   3100 C C   . ILE C 1 115 ? 54.04346 -6.65911  45.06548  1.000 21.33197 ? 115 ILE C C   1 
ATOM   3101 O O   . ILE C 1 115 ? 54.06439 -6.68693  46.30057  1.000 21.67602 ? 115 ILE C O   1 
ATOM   3102 C CB  . ILE C 1 115 ? 53.99821 -8.92466  43.94611  1.000 20.91941 ? 115 ILE C CB  1 
ATOM   3103 C CG1 . ILE C 1 115 ? 54.68774 -9.87373  42.98786  1.000 25.89429 ? 115 ILE C CG1 1 
ATOM   3104 C CG2 . ILE C 1 115 ? 52.59157 -8.57759  43.44866  1.000 23.23564 ? 115 ILE C CG2 1 
ATOM   3105 C CD1 . ILE C 1 115 ? 53.75541 -10.97288 42.52513  1.000 24.47237 ? 115 ILE C CD1 1 
ATOM   3106 N N   . ILE C 1 116 ? 53.34318 -5.76989  44.36729  1.000 18.22310 ? 116 ILE C N   1 
ATOM   3107 C CA  . ILE C 1 116 ? 52.32954 -4.90380  44.94925  1.000 18.06093 ? 116 ILE C CA  1 
ATOM   3108 C C   . ILE C 1 116 ? 51.00407 -5.34117  44.35399  1.000 17.57004 ? 116 ILE C C   1 
ATOM   3109 O O   . ILE C 1 116 ? 50.94959 -5.74394  43.18344  1.000 16.98076 ? 116 ILE C O   1 
ATOM   3110 C CB  . ILE C 1 116 ? 52.63866 -3.43090  44.62910  1.000 16.33753 ? 116 ILE C CB  1 
ATOM   3111 C CG1 . ILE C 1 116 ? 53.94115 -3.03028  45.32726  1.000 18.86460 ? 116 ILE C CG1 1 
ATOM   3112 C CG2 . ILE C 1 116 ? 51.53955 -2.52682  45.09873  1.000 19.12518 ? 116 ILE C CG2 1 
ATOM   3113 C CD1 . ILE C 1 116 ? 54.40764 -1.65375  44.97987  1.000 20.07303 ? 116 ILE C CD1 1 
ATOM   3114 N N   . SER C 1 117 ? 49.94277 -5.31439  45.17099  1.000 18.10455 ? 117 SER C N   1 
ATOM   3115 C CA  . SER C 1 117 ? 48.66058 -5.88655  44.76639  1.000 16.95695 ? 117 SER C CA  1 
ATOM   3116 C C   . SER C 1 117 ? 47.48046 -5.00681  45.18190  1.000 16.86865 ? 117 SER C C   1 
ATOM   3117 O O   . SER C 1 117 ? 47.58597 -4.13859  46.05389  1.000 18.66521 ? 117 SER C O   1 
ATOM   3118 C CB  . SER C 1 117 ? 48.42194 -7.25165  45.43532  1.000 18.76745 ? 117 SER C CB  1 
ATOM   3119 O OG  . SER C 1 117 ? 49.43841 -8.17070  45.12143  1.000 21.36593 ? 117 SER C OG  1 
ATOM   3120 N N   . MET C 1 118 ? 46.33498 -5.28680  44.56264  1.000 16.39161 ? 118 MET C N   1 
ATOM   3121 C CA  . MET C 1 118 ? 45.02961 -4.88286  45.06504  1.000 16.51277 ? 118 MET C CA  1 
ATOM   3122 C C   . MET C 1 118 ? 44.44417 -6.08339  45.79151  1.000 17.81600 ? 118 MET C C   1 
ATOM   3123 O O   . MET C 1 118 ? 44.81183 -7.22532  45.51041  1.000 18.62699 ? 118 MET C O   1 
ATOM   3124 C CB  . MET C 1 118 ? 44.11874 -4.54064  43.88268  1.000 19.35827 ? 118 MET C CB  1 
ATOM   3125 C CG  . MET C 1 118 ? 44.56741 -3.35097  43.11064  1.000 24.68340 ? 118 MET C CG  1 
ATOM   3126 S SD  . MET C 1 118 ? 43.30800 -3.11023  41.86037  0.524 32.63952 ? 118 MET C SD  1 
ATOM   3127 C CE  . MET C 1 118 ? 43.61017 -4.42308  40.73412  1.000 25.84864 ? 118 MET C CE  1 
ATOM   3128 N N   . VAL C 1 119 ? 43.53235 -5.83076  46.72514  1.000 17.52034 ? 119 VAL C N   1 
ATOM   3129 C CA  . VAL C 1 119 ? 43.15859 -6.85331  47.70118  1.000 17.94366 ? 119 VAL C CA  1 
ATOM   3130 C C   . VAL C 1 119 ? 41.65990 -7.09940  47.68597  1.000 18.27959 ? 119 VAL C C   1 
ATOM   3131 O O   . VAL C 1 119 ? 40.86296 -6.15916  47.60602  1.000 18.54249 ? 119 VAL C O   1 
ATOM   3132 C CB  . VAL C 1 119 ? 43.64694 -6.51852  49.12434  1.000 21.90459 ? 119 VAL C CB  1 
ATOM   3133 C CG1 . VAL C 1 119 ? 45.16053 -6.59688  49.16997  1.000 21.65349 ? 119 VAL C CG1 1 
ATOM   3134 C CG2 . VAL C 1 119 ? 43.15282 -5.14960  49.54584  1.000 22.86959 ? 119 VAL C CG2 1 
ATOM   3135 N N   . GLY C 1 120 ? 41.29189 -8.38602  47.74199  1.000 15.87744 ? 120 GLY C N   1 
ATOM   3136 C CA  . GLY C 1 120 ? 39.93292 -8.81060  47.91999  1.000 17.98774 ? 120 GLY C CA  1 
ATOM   3137 C C   . GLY C 1 120 ? 39.70336 -9.42530  49.28694  1.000 18.55960 ? 120 GLY C C   1 
ATOM   3138 O O   . GLY C 1 120 ? 40.46921 -9.21954  50.23548  1.000 21.69064 ? 120 GLY C O   1 
ATOM   3139 N N   . SER C 1 121 ? 38.61282 -10.16900 49.39175  1.000 21.51209 ? 121 SER C N   1 
ATOM   3140 C CA  . SER C 1 121 ? 38.29000 -10.81524 50.65142  1.000 22.98321 ? 121 SER C CA  1 
ATOM   3141 C C   . SER C 1 121 ? 39.22734 -11.99317 50.88965  1.000 22.12411 ? 121 SER C C   1 
ATOM   3142 O O   . SER C 1 121 ? 39.71670 -12.63061 49.95238  1.000 21.37727 ? 121 SER C O   1 
ATOM   3143 C CB  . SER C 1 121 ? 36.84380 -11.30324 50.63356  1.000 25.85828 ? 121 SER C CB  1 
ATOM   3144 O OG  . SER C 1 121 ? 36.64168 -12.25060 49.60701  1.000 28.97342 ? 121 SER C OG  1 
ATOM   3145 N N   . GLY C 1 122 ? 39.47726 -12.27332 52.15888  1.000 24.25275 ? 122 GLY C N   1 
ATOM   3146 C CA  . GLY C 1 122 ? 40.31917 -13.40740 52.50751  1.000 25.45039 ? 122 GLY C CA  1 
ATOM   3147 C C   . GLY C 1 122 ? 41.69105 -13.29596 51.86884  1.000 22.23916 ? 122 GLY C C   1 
ATOM   3148 O O   . GLY C 1 122 ? 42.41021 -12.30250 52.04589  1.000 25.56953 ? 122 GLY C O   1 
ATOM   3149 N N   . SER C 1 123 ? 42.07629 -14.32252 51.11321  1.000 23.93073 ? 123 SER C N   1 
ATOM   3150 C CA  . SER C 1 123 ? 43.39287 -14.36321 50.49103  1.000 22.16221 ? 123 SER C CA  1 
ATOM   3151 C C   . SER C 1 123 ? 43.39629 -13.82913 49.06294  1.000 22.63392 ? 123 SER C C   1 
ATOM   3152 O O   . SER C 1 123 ? 44.45445 -13.83160 48.42118  1.000 22.85462 ? 123 SER C O   1 
ATOM   3153 C CB  . SER C 1 123 ? 43.93941 -15.79245 50.50504  1.000 26.45146 ? 123 SER C CB  1 
ATOM   3154 O OG  . SER C 1 123 ? 43.12846 -16.62541 49.70300  1.000 29.92904 ? 123 SER C OG  1 
ATOM   3155 N N   . ILE C 1 124 ? 42.24924 -13.37028 48.55537  1.000 20.55015 ? 124 ILE C N   1 
ATOM   3156 C CA  . ILE C 1 124 ? 42.18517 -12.87915 47.18437  1.000 20.02638 ? 124 ILE C CA  1 
ATOM   3157 C C   . ILE C 1 124 ? 43.05482 -11.64198 47.05386  1.000 19.15646 ? 124 ILE C C   1 
ATOM   3158 O O   . ILE C 1 124 ? 42.95168 -10.69441 47.84744  1.000 19.04795 ? 124 ILE C O   1 
ATOM   3159 C CB  . ILE C 1 124 ? 40.73401 -12.57486 46.78705  1.000 19.03788 ? 124 ILE C CB  1 
ATOM   3160 C CG1 . ILE C 1 124 ? 39.90684 -13.85638 46.65875  1.000 17.35805 ? 124 ILE C CG1 1 
ATOM   3161 C CG2 . ILE C 1 124 ? 40.67126 -11.82101 45.45527  1.000 20.19629 ? 124 ILE C CG2 1 
ATOM   3162 C CD1 . ILE C 1 124 ? 38.43228 -13.56946 46.59969  1.000 18.75401 ? 124 ILE C CD1 1 
ATOM   3163 N N   . ALA C 1 125 ? 43.91118 -11.63742 46.03827  1.000 18.06598 ? 125 ALA C N   1 
ATOM   3164 C CA  . ALA C 1 125 ? 44.78256 -10.50106 45.79292  1.000 17.80333 ? 125 ALA C CA  1 
ATOM   3165 C C   . ALA C 1 125 ? 45.21421 -10.56191 44.33985  1.000 18.44686 ? 125 ALA C C   1 
ATOM   3166 O O   . ALA C 1 125 ? 45.50794 -11.64222 43.82386  1.000 19.74084 ? 125 ALA C O   1 
ATOM   3167 C CB  . ALA C 1 125 ? 46.01327 -10.52894 46.70391  1.000 20.21187 ? 125 ALA C CB  1 
ATOM   3168 N N   . ALA C 1 126 ? 45.24103 -9.40314  43.68891  1.000 18.40738 ? 126 ALA C N   1 
ATOM   3169 C CA  . ALA C 1 126 ? 45.57351 -9.30701  42.27341  1.000 18.44059 ? 126 ALA C CA  1 
ATOM   3170 C C   . ALA C 1 126 ? 46.86549 -8.52368  42.13191  1.000 17.30023 ? 126 ALA C C   1 
ATOM   3171 O O   . ALA C 1 126 ? 46.95601 -7.38094  42.59326  1.000 17.73502 ? 126 ALA C O   1 
ATOM   3172 C CB  . ALA C 1 126 ? 44.45599 -8.60394  41.50000  1.000 17.74115 ? 126 ALA C CB  1 
ATOM   3173 N N   . ALA C 1 127 ? 47.84915 -9.12097  41.46748  1.000 16.80449 ? 127 ALA C N   1 
ATOM   3174 C CA  . ALA C 1 127 ? 49.13222 -8.45440  41.28223  1.000 15.34964 ? 127 ALA C CA  1 
ATOM   3175 C C   . ALA C 1 127 ? 48.96811 -7.24369  40.36920  1.000 15.86889 ? 127 ALA C C   1 
ATOM   3176 O O   . ALA C 1 127 ? 48.31301 -7.32173  39.32453  1.000 18.94022 ? 127 ALA C O   1 
ATOM   3177 C CB  . ALA C 1 127 ? 50.13746 -9.42603  40.66729  1.000 17.36322 ? 127 ALA C CB  1 
ATOM   3178 N N   . THR C 1 128 ? 49.56439 -6.11549  40.76597  1.000 14.69158 ? 128 THR C N   1 
ATOM   3179 C CA  . THR C 1 128 ? 49.55238 -4.92124  39.93676  1.000 16.20293 ? 128 THR C CA  1 
ATOM   3180 C C   . THR C 1 128 ? 50.93920 -4.40448  39.58681  1.000 14.61767 ? 128 THR C C   1 
ATOM   3181 O O   . THR C 1 128 ? 51.09519 -3.77758  38.53691  1.000 16.35043 ? 128 THR C O   1 
ATOM   3182 C CB  . THR C 1 128 ? 48.76193 -3.79358  40.60776  1.000 18.18753 ? 128 THR C CB  1 
ATOM   3183 O OG1 . THR C 1 128 ? 49.37042 -3.46546  41.86141  1.000 21.16354 ? 128 THR C OG1 1 
ATOM   3184 C CG2 . THR C 1 128 ? 47.32378 -4.22841  40.85605  1.000 19.26118 ? 128 THR C CG2 1 
ATOM   3185 N N   . MET C 1 129 ? 51.94155 -4.63748  40.42505  1.000 14.93785 ? 129 MET C N   1 
ATOM   3186 C CA  . MET C 1 129 ? 53.32364 -4.38284  40.04892  1.000 13.78989 ? 129 MET C CA  1 
ATOM   3187 C C   . MET C 1 129 ? 54.14576 -5.59242  40.46600  1.000 15.54806 ? 129 MET C C   1 
ATOM   3188 O O   . MET C 1 129 ? 53.96400 -6.11886  41.56563  1.000 17.16145 ? 129 MET C O   1 
ATOM   3189 C CB  . MET C 1 129 ? 53.88326 -3.14941  40.76065  1.000 16.71685 ? 129 MET C CB  1 
ATOM   3190 C CG  . MET C 1 129 ? 53.25709 -1.83691  40.34591  1.000 14.82659 ? 129 MET C CG  1 
ATOM   3191 S SD  . MET C 1 129 ? 54.01122 -0.38783  41.13226  1.000 18.89022 ? 129 MET C SD  1 
ATOM   3192 C CE  . MET C 1 129 ? 55.70932 -0.50692  40.61332  1.000 16.30134 ? 129 MET C CE  1 
ATOM   3193 N N   . VAL C 1 130 ? 55.05182 -6.03630  39.59588  1.000 12.89879 ? 130 VAL C N   1 
ATOM   3194 C CA  . VAL C 1 130 ? 55.89777 -7.19559  39.87451  1.000 14.11785 ? 130 VAL C CA  1 
ATOM   3195 C C   . VAL C 1 130 ? 57.32890 -6.85624  39.48987  1.000 16.08621 ? 130 VAL C C   1 
ATOM   3196 O O   . VAL C 1 130 ? 57.57400 -6.28589  38.41958  1.000 14.36489 ? 130 VAL C O   1 
ATOM   3197 C CB  . VAL C 1 130 ? 55.42965 -8.43977  39.08926  1.000 14.87585 ? 130 VAL C CB  1 
ATOM   3198 C CG1 . VAL C 1 130 ? 56.20825 -9.65239  39.52723  1.000 18.05704 ? 130 VAL C CG1 1 
ATOM   3199 C CG2 . VAL C 1 130 ? 53.95734 -8.67918  39.27680  1.000 19.36316 ? 130 VAL C CG2 1 
ATOM   3200 N N   . SER C 1 131 ? 58.28278 -7.22768  40.34532  1.000 14.39502 ? 131 SER C N   1 
ATOM   3201 C CA  . SER C 1 131 ? 59.66602 -6.83175  40.13302  1.000 14.56891 ? 131 SER C CA  1 
ATOM   3202 C C   . SER C 1 131 ? 60.59879 -8.03111  40.21354  1.000 16.91183 ? 131 SER C C   1 
ATOM   3203 O O   . SER C 1 131 ? 60.35352 -8.98465  40.95827  1.000 18.52979 ? 131 SER C O   1 
ATOM   3204 C CB  . SER C 1 131 ? 60.08019 -5.79404  41.16438  1.000 17.90810 ? 131 SER C CB  1 
ATOM   3205 O OG  . SER C 1 131 ? 61.29665 -5.17907  40.81821  1.000 20.69439 ? 131 SER C OG  1 
ATOM   3206 N N   . TRP C 1 132 ? 61.68490 -7.94714  39.44050  1.000 15.36422 ? 132 TRP C N   1 
ATOM   3207 C CA  . TRP C 1 132 ? 62.77502 -8.91998  39.44075  1.000 17.12141 ? 132 TRP C CA  1 
ATOM   3208 C C   . TRP C 1 132 ? 64.06706 -8.14785  39.63972  1.000 18.41316 ? 132 TRP C C   1 
ATOM   3209 O O   . TRP C 1 132 ? 64.41077 -7.29460  38.81476  1.000 17.90759 ? 132 TRP C O   1 
ATOM   3210 C CB  . TRP C 1 132 ? 62.84017 -9.66465  38.10225  1.000 17.37634 ? 132 TRP C CB  1 
ATOM   3211 C CG  . TRP C 1 132 ? 61.70536 -10.57159 37.87174  1.000 17.53273 ? 132 TRP C CG  1 
ATOM   3212 C CD1 . TRP C 1 132 ? 61.67328 -11.91932 38.11075  1.000 17.69511 ? 132 TRP C CD1 1 
ATOM   3213 C CD2 . TRP C 1 132 ? 60.42269 -10.22994 37.33770  1.000 15.77219 ? 132 TRP C CD2 1 
ATOM   3214 N NE1 . TRP C 1 132 ? 60.45446 -12.42754 37.77340  1.000 19.29492 ? 132 TRP C NE1 1 
ATOM   3215 C CE2 . TRP C 1 132 ? 59.66122 -11.41619 37.29658  1.000 16.52723 ? 132 TRP C CE2 1 
ATOM   3216 C CE3 . TRP C 1 132 ? 59.84048 -9.03575  36.88993  1.000 14.67936 ? 132 TRP C CE3 1 
ATOM   3217 C CZ2 . TRP C 1 132 ? 58.35398 -11.44514 36.82611  1.000 19.63624 ? 132 TRP C CZ2 1 
ATOM   3218 C CZ3 . TRP C 1 132 ? 58.54409 -9.06840  36.42868  1.000 16.86723 ? 132 TRP C CZ3 1 
ATOM   3219 C CH2 . TRP C 1 132 ? 57.81390 -10.26774 36.39994  1.000 18.63535 ? 132 TRP C CH2 1 
ATOM   3220 N N   . LYS C 1 133 ? 64.80446 -8.46887  40.70700  1.000 19.50801 ? 133 LYS C N   1 
ATOM   3221 C CA  . LYS C 1 133 ? 65.97105 -7.66099  41.04753  1.000 21.00259 ? 133 LYS C CA  1 
ATOM   3222 C C   . LYS C 1 133 ? 67.09224 -7.77760  40.02436  1.000 20.78774 ? 133 LYS C C   1 
ATOM   3223 O O   . LYS C 1 133 ? 67.87569 -6.83328  39.86982  1.000 21.78563 ? 133 LYS C O   1 
ATOM   3224 C CB  . LYS C 1 133 ? 66.46952 -7.99338  42.45309  1.000 23.75093 ? 133 LYS C CB  1 
ATOM   3225 C CG  . LYS C 1 133 ? 65.54181 -7.47569  43.53294  1.000 23.53825 ? 133 LYS C CG  1 
ATOM   3226 C CD  . LYS C 1 133 ? 66.06731 -7.75608  44.92817  1.000 26.65345 ? 133 LYS C CD  1 
ATOM   3227 C CE  . LYS C 1 133 ? 65.52418 -6.73873  45.91285  1.000 31.43951 ? 133 LYS C CE  1 
ATOM   3228 N NZ  . LYS C 1 133 ? 64.08546 -6.98993  46.18483  1.000 34.76807 ? 133 LYS C NZ  1 
ATOM   3229 N N   . SER C 1 134 ? 67.18674 -8.90123  39.30144  1.000 20.13249 ? 134 SER C N   1 
ATOM   3230 C CA  . SER C 1 134 ? 68.35362 -9.11252  38.45074  1.000 21.03238 ? 134 SER C CA  1 
ATOM   3231 C C   . SER C 1 134 ? 68.01854 -9.86127  37.16323  1.000 21.61164 ? 134 SER C C   1 
ATOM   3232 O O   . SER C 1 134 ? 68.85997 -10.59861 36.63681  1.000 24.30301 ? 134 SER C O   1 
ATOM   3233 C CB  . SER C 1 134 ? 69.48414 -9.78426  39.24896  1.000 24.72201 ? 134 SER C CB  1 
ATOM   3234 O OG  . SER C 1 134 ? 69.05732 -11.03369 39.74911  1.000 32.11674 ? 134 SER C OG  1 
ATOM   3235 N N   . THR C 1 135 ? 66.81006 -9.67101  36.63845  1.000 17.30754 ? 135 THR C N   1 
ATOM   3236 C CA  . THR C 1 135 ? 66.38589 -10.21192 35.35587  1.000 16.62553 ? 135 THR C CA  1 
ATOM   3237 C C   . THR C 1 135 ? 65.88334 -9.04008  34.52952  1.000 19.58236 ? 135 THR C C   1 
ATOM   3238 O O   . THR C 1 135 ? 65.07109 -8.24866  35.01515  1.000 20.15795 ? 135 THR C O   1 
ATOM   3239 C CB  . THR C 1 135 ? 65.26308 -11.24723 35.54647  1.000 21.81702 ? 135 THR C CB  1 
ATOM   3240 O OG1 . THR C 1 135 ? 65.72392 -12.30327 36.40505  1.000 18.64338 ? 135 THR C OG1 1 
ATOM   3241 C CG2 . THR C 1 135 ? 64.80979 -11.84203 34.21233  1.000 17.77317 ? 135 THR C CG2 1 
ATOM   3242 N N   . LYS C 1 136 ? 66.37873 -8.91090  33.30382  1.000 18.14154 ? 136 LYS C N   1 
ATOM   3243 C CA  . LYS C 1 136 ? 66.03743 -7.77896  32.45580  1.000 18.16143 ? 136 LYS C CA  1 
ATOM   3244 C C   . LYS C 1 136 ? 64.92066 -8.20978  31.51835  1.000 17.74829 ? 136 LYS C C   1 
ATOM   3245 O O   . LYS C 1 136 ? 64.86501 -9.36959  31.09706  1.000 18.46794 ? 136 LYS C O   1 
ATOM   3246 C CB  . LYS C 1 136 ? 67.24835 -7.37015  31.61156  1.000 19.17576 ? 136 LYS C CB  1 
ATOM   3247 C CG  . LYS C 1 136 ? 68.29606 -6.58674  32.37643  1.000 22.89405 ? 136 LYS C CG  1 
ATOM   3248 C CD  . LYS C 1 136 ? 67.76735 -5.22126  32.72715  1.000 23.58092 ? 136 LYS C CD  1 
ATOM   3249 C CE  . LYS C 1 136 ? 68.62637 -4.57008  33.78174  1.000 25.14485 ? 136 LYS C CE  1 
ATOM   3250 N NZ  . LYS C 1 136 ? 68.04341 -3.26126  34.13220  1.000 17.83826 ? 136 LYS C NZ  1 
ATOM   3251 N N   . ALA C 1 137 ? 64.00757 -7.29025  31.21963  1.000 15.09655 ? 137 ALA C N   1 
ATOM   3252 C CA  . ALA C 1 137 ? 63.04470 -7.55097  30.16462  1.000 14.11732 ? 137 ALA C CA  1 
ATOM   3253 C C   . ALA C 1 137 ? 63.73914 -7.41446  28.81552  1.000 15.35521 ? 137 ALA C C   1 
ATOM   3254 O O   . ALA C 1 137 ? 64.56268 -6.51619  28.60749  1.000 15.78059 ? 137 ALA C O   1 
ATOM   3255 C CB  . ALA C 1 137 ? 61.88038 -6.55925  30.26367  1.000 14.61077 ? 137 ALA C CB  1 
ATOM   3256 N N   . ALA C 1 138 ? 63.40164 -8.31462  27.89627  1.000 14.16307 ? 138 ALA C N   1 
ATOM   3257 C CA  . ALA C 1 138 ? 63.89621 -8.24526  26.52968  1.000 14.37774 ? 138 ALA C CA  1 
ATOM   3258 C C   . ALA C 1 138 ? 62.93239 -9.02275  25.65230  1.000 14.40480 ? 138 ALA C C   1 
ATOM   3259 O O   . ALA C 1 138 ? 62.21979 -9.90693  26.12800  1.000 14.34269 ? 138 ALA C O   1 
ATOM   3260 C CB  . ALA C 1 138 ? 65.30575 -8.84456  26.40793  1.000 16.31149 ? 138 ALA C CB  1 
ATOM   3261 N N   . ALA C 1 139 ? 62.91074 -8.68347  24.36463  1.000 14.34284 ? 139 ALA C N   1 
ATOM   3262 C CA  . ALA C 1 139 ? 62.03698 -9.39750  23.44881  1.000 14.64426 ? 139 ALA C CA  1 
ATOM   3263 C C   . ALA C 1 139 ? 62.48912 -10.84666 23.32655  1.000 15.71464 ? 139 ALA C C   1 
ATOM   3264 O O   . ALA C 1 139 ? 63.68492 -11.13635 23.32191  1.000 15.21493 ? 139 ALA C O   1 
ATOM   3265 C CB  . ALA C 1 139 ? 62.02538 -8.73709  22.06861  1.000 16.12209 ? 139 ALA C CB  1 
ATOM   3266 N N   . GLY C 1 140 ? 61.52359 -11.76246 23.26382  1.000 13.94046 ? 140 GLY C N   1 
ATOM   3267 C CA  . GLY C 1 140 ? 61.81805 -13.15881 23.00387  1.000 15.19206 ? 140 GLY C CA  1 
ATOM   3268 C C   . GLY C 1 140 ? 61.95499 -14.05188 24.21657  1.000 17.20648 ? 140 GLY C C   1 
ATOM   3269 O O   . GLY C 1 140 ? 62.22095 -15.25089 24.04817  1.000 20.61498 ? 140 GLY C O   1 
ATOM   3270 N N   . ILE C 1 141 ? 61.84178 -13.51245 25.42227  1.000 15.16677 ? 141 ILE C N   1 
ATOM   3271 C CA  . ILE C 1 141 ? 61.86380 -14.32644 26.62990  1.000 15.39108 ? 141 ILE C CA  1 
ATOM   3272 C C   . ILE C 1 141 ? 60.43897 -14.51622 27.13468  1.000 16.38859 ? 141 ILE C C   1 
ATOM   3273 O O   . ILE C 1 141 ? 59.51060 -13.80239 26.75532  1.000 15.94230 ? 141 ILE C O   1 
ATOM   3274 C CB  . ILE C 1 141 ? 62.78703 -13.77561 27.73458  1.000 15.35352 ? 141 ILE C CB  1 
ATOM   3275 C CG1 . ILE C 1 141 ? 62.24188 -12.44483 28.27510  1.000 16.13591 ? 141 ILE C CG1 1 
ATOM   3276 C CG2 . ILE C 1 141 ? 64.22985 -13.66098 27.21397  1.000 15.02930 ? 141 ILE C CG2 1 
ATOM   3277 C CD1 . ILE C 1 141 ? 63.05468 -11.87013 29.41027  1.000 18.62817 ? 141 ILE C CD1 1 
ATOM   3278 N N   . SER C 1 142 ? 60.26751 -15.49907 28.00922  1.000 16.10352 ? 142 SER C N   1 
ATOM   3279 C CA  . SER C 1 142 ? 58.94169 -15.93426 28.42042  1.000 15.34164 ? 142 SER C CA  1 
ATOM   3280 C C   . SER C 1 142 ? 58.49661 -15.23665 29.69620  1.000 17.14775 ? 142 SER C C   1 
ATOM   3281 O O   . SER C 1 142 ? 59.29070 -14.94606 30.59090  1.000 17.36315 ? 142 SER C O   1 
ATOM   3282 C CB  . SER C 1 142 ? 58.93572 -17.44523 28.66923  1.000 20.33588 ? 142 SER C CB  1 
ATOM   3283 O OG  . SER C 1 142 ? 59.71057 -17.74983 29.81958  1.000 23.79272 ? 142 SER C OG  1 
ATOM   3284 N N   . PHE C 1 143 ? 57.19456 -14.99165 29.77538  1.000 16.02646 ? 143 PHE C N   1 
ATOM   3285 C CA  . PHE C 1 143 ? 56.53066 -14.53398 30.98641  1.000 15.69068 ? 143 PHE C CA  1 
ATOM   3286 C C   . PHE C 1 143 ? 55.50785 -15.60357 31.32754  1.000 14.82504 ? 143 PHE C C   1 
ATOM   3287 O O   . PHE C 1 143 ? 54.66523 -15.94809 30.49297  1.000 16.58873 ? 143 PHE C O   1 
ATOM   3288 C CB  . PHE C 1 143 ? 55.83146 -13.20395 30.73265  1.000 15.53223 ? 143 PHE C CB  1 
ATOM   3289 C CG  . PHE C 1 143 ? 55.03261 -12.69834 31.90973  1.000 16.37392 ? 143 PHE C CG  1 
ATOM   3290 C CD1 . PHE C 1 143 ? 55.67003 -12.11482 32.99189  1.000 15.87801 ? 143 PHE C CD1 1 
ATOM   3291 C CD2 . PHE C 1 143 ? 53.63577 -12.78409 31.92367  1.000 14.99819 ? 143 PHE C CD2 1 
ATOM   3292 C CE1 . PHE C 1 143 ? 54.95840 -11.63413 34.06425  1.000 17.48559 ? 143 PHE C CE1 1 
ATOM   3293 C CE2 . PHE C 1 143 ? 52.91862 -12.30379 32.99438  1.000 15.89282 ? 143 PHE C CE2 1 
ATOM   3294 C CZ  . PHE C 1 143 ? 53.56485 -11.72620 34.06529  1.000 16.48252 ? 143 PHE C CZ  1 
ATOM   3295 N N   . LYS C 1 144 ? 55.61706 -16.17268 32.51987  1.000 15.56691 ? 144 LYS C N   1 
ATOM   3296 C CA  . LYS C 1 144 ? 54.73442 -17.25501 32.92931  1.000 17.48981 ? 144 LYS C CA  1 
ATOM   3297 C C   . LYS C 1 144 ? 53.94894 -16.80756 34.14729  1.000 17.07620 ? 144 LYS C C   1 
ATOM   3298 O O   . LYS C 1 144 ? 54.48877 -16.15729 35.04776  1.000 17.79372 ? 144 LYS C O   1 
ATOM   3299 C CB  . LYS C 1 144 ? 55.53264 -18.52173 33.23854  1.000 19.66362 ? 144 LYS C CB  1 
ATOM   3300 C CG  . LYS C 1 144 ? 56.16104 -19.11230 31.99916  1.000 20.41096 ? 144 LYS C CG  1 
ATOM   3301 C CD  . LYS C 1 144 ? 57.06647 -20.28348 32.34759  1.000 23.05314 ? 144 LYS C CD  1 
ATOM   3302 C CE  . LYS C 1 144 ? 57.85540 -20.73719 31.13255  1.000 26.00675 ? 144 LYS C CE  1 
ATOM   3303 N NZ  . LYS C 1 144 ? 56.96223 -21.20734 30.04118  1.000 27.44814 ? 144 LYS C NZ  1 
ATOM   3304 N N   . TYR C 1 145 ? 52.66889 -17.15180 34.17226  1.000 14.79566 ? 145 TYR C N   1 
ATOM   3305 C CA  . TYR C 1 145 ? 51.80066 -16.60108 35.19458  1.000 14.78257 ? 145 TYR C CA  1 
ATOM   3306 C C   . TYR C 1 145 ? 50.66306 -17.56797 35.46018  1.000 17.57007 ? 145 TYR C C   1 
ATOM   3307 O O   . TYR C 1 145 ? 50.40170 -18.48798 34.68112  1.000 17.27181 ? 145 TYR C O   1 
ATOM   3308 C CB  . TYR C 1 145 ? 51.21611 -15.26248 34.74291  1.000 16.88020 ? 145 TYR C CB  1 
ATOM   3309 C CG  . TYR C 1 145 ? 50.30538 -15.40584 33.53686  1.000 15.97055 ? 145 TYR C CG  1 
ATOM   3310 C CD1 . TYR C 1 145 ? 50.79808 -15.31890 32.24815  1.000 15.66944 ? 145 TYR C CD1 1 
ATOM   3311 C CD2 . TYR C 1 145 ? 48.95026 -15.67293 33.69642  1.000 17.06690 ? 145 TYR C CD2 1 
ATOM   3312 C CE1 . TYR C 1 145 ? 49.96297 -15.46529 31.14496  1.000 18.40157 ? 145 TYR C CE1 1 
ATOM   3313 C CE2 . TYR C 1 145 ? 48.12368 -15.80877 32.62551  1.000 18.13476 ? 145 TYR C CE2 1 
ATOM   3314 C CZ  . TYR C 1 145 ? 48.62514 -15.71615 31.35098  1.000 21.95305 ? 145 TYR C CZ  1 
ATOM   3315 O OH  . TYR C 1 145 ? 47.77482 -15.87333 30.28777  1.000 24.45009 ? 145 TYR C OH  1 
ATOM   3316 N N   . LEU C 1 146 ? 49.95424 -17.30925 36.55386  1.000 16.57206 ? 146 LEU C N   1 
ATOM   3317 C CA  . LEU C 1 146 ? 48.74909 -18.05224 36.90798  1.000 16.11499 ? 146 LEU C CA  1 
ATOM   3318 C C   . LEU C 1 146 ? 47.59231 -17.06435 36.92734  1.000 15.97283 ? 146 LEU C C   1 
ATOM   3319 O O   . LEU C 1 146 ? 47.53956 -16.17944 37.79013  1.000 19.97677 ? 146 LEU C O   1 
ATOM   3320 C CB  . LEU C 1 146 ? 48.90980 -18.71180 38.27324  1.000 19.20033 ? 146 LEU C CB  1 
ATOM   3321 C CG  . LEU C 1 146 ? 47.80470 -19.70834 38.61253  1.000 21.13905 ? 146 LEU C CG  1 
ATOM   3322 C CD1 . LEU C 1 146 ? 47.93617 -20.94516 37.73910  1.000 22.27085 ? 146 LEU C CD1 1 
ATOM   3323 C CD2 . LEU C 1 146 ? 47.89743 -20.08134 40.07298  1.000 23.53345 ? 146 LEU C CD2 1 
ATOM   3324 N N   . GLY C 1 147 ? 46.68282 -17.19611 35.96798  1.000 16.18649 ? 147 GLY C N   1 
ATOM   3325 C CA  . GLY C 1 147 ? 45.51733 -16.33302 35.91663  1.000 18.43126 ? 147 GLY C CA  1 
ATOM   3326 C C   . GLY C 1 147 ? 44.39742 -16.92601 36.75293  1.000 19.76524 ? 147 GLY C C   1 
ATOM   3327 O O   . GLY C 1 147 ? 44.18216 -18.13498 36.76388  1.000 21.80449 ? 147 GLY C O   1 
ATOM   3328 N N   . LYS C 1 148 ? 43.70499 -16.06709 37.48239  1.000 16.94714 ? 148 LYS C N   1 
ATOM   3329 C CA  . LYS C 1 148 ? 42.53087 -16.54549 38.19207  1.000 18.64916 ? 148 LYS C CA  1 
ATOM   3330 C C   . LYS C 1 148 ? 41.40032 -15.54073 38.05717  1.000 16.28812 ? 148 LYS C C   1 
ATOM   3331 O O   . LYS C 1 148 ? 41.52521 -14.52073 37.37401  1.000 17.89197 ? 148 LYS C O   1 
ATOM   3332 C CB  . LYS C 1 148 ? 42.87703 -17.10753 39.57016  1.000 28.75881 ? 148 LYS C CB  1 
ATOM   3333 C CG  . LYS C 1 148 ? 43.51484 -16.17516 40.51094  1.000 28.60366 ? 148 LYS C CG  1 
ATOM   3334 C CD  . LYS C 1 148 ? 43.81455 -16.94397 41.79938  1.000 32.87390 ? 148 LYS C CD  1 
ATOM   3335 C CE  . LYS C 1 148 ? 44.93800 -17.94906 41.57803  1.000 33.48764 ? 148 LYS C CE  1 
ATOM   3336 N NZ  . LYS C 1 148 ? 45.32661 -18.67317 42.82390  1.000 37.92930 ? 148 LYS C NZ  1 
ATOM   3337 N N   . ASN C 1 149 ? 40.25618 -15.87993 38.64191  1.000 17.55871 ? 149 ASN C N   1 
ATOM   3338 C CA  . ASN C 1 149 ? 39.05551 -15.08296 38.44866  1.000 17.72651 ? 149 ASN C CA  1 
ATOM   3339 C C   . ASN C 1 149 ? 38.21527 -15.14937 39.71545  1.000 17.82781 ? 149 ASN C C   1 
ATOM   3340 O O   . ASN C 1 149 ? 38.43980 -15.98626 40.59269  1.000 17.97472 ? 149 ASN C O   1 
ATOM   3341 C CB  . ASN C 1 149 ? 38.28314 -15.51547 37.18776  1.000 17.68109 ? 149 ASN C CB  1 
ATOM   3342 C CG  . ASN C 1 149 ? 37.46783 -16.76539 37.40225  1.000 20.27528 ? 149 ASN C CG  1 
ATOM   3343 O OD1 . ASN C 1 149 ? 36.28988 -16.68487 37.74036  1.000 17.94185 ? 149 ASN C OD1 1 
ATOM   3344 N ND2 . ASN C 1 149 ? 38.07652 -17.92772 37.19159  1.000 19.67750 ? 149 ASN C ND2 1 
ATOM   3345 N N   . LEU C 1 150 ? 37.24378 -14.23631 39.80759  1.000 15.73099 ? 150 LEU C N   1 
ATOM   3346 C CA  . LEU C 1 150 ? 36.45346 -14.07165 41.02175  1.000 18.33851 ? 150 LEU C CA  1 
ATOM   3347 C C   . LEU C 1 150 ? 35.19435 -14.91984 41.04399  1.000 18.33953 ? 150 LEU C C   1 
ATOM   3348 O O   . LEU C 1 150 ? 34.53432 -14.98656 42.08942  1.000 19.40292 ? 150 LEU C O   1 
ATOM   3349 C CB  . LEU C 1 150 ? 36.04200 -12.60746 41.17140  1.000 16.65648 ? 150 LEU C CB  1 
ATOM   3350 C CG  . LEU C 1 150 ? 37.25694 -11.71948 41.44275  1.000 16.42713 ? 150 LEU C CG  1 
ATOM   3351 C CD1 . LEU C 1 150 ? 36.86383 -10.24178 41.36611  1.000 17.05742 ? 150 LEU C CD1 1 
ATOM   3352 C CD2 . LEU C 1 150 ? 37.93480 -12.04673 42.77447  1.000 20.29198 ? 150 LEU C CD2 1 
ATOM   3353 N N   . ILE C 1 151 ? 34.82768 -15.52870 39.92326  1.000 17.23231 ? 151 ILE C N   1 
ATOM   3354 C CA  . ILE C 1 151 ? 33.60205 -16.31779 39.85721  1.000 18.49631 ? 151 ILE C CA  1 
ATOM   3355 C C   . ILE C 1 151 ? 33.85504 -17.77462 40.21849  1.000 21.28087 ? 151 ILE C C   1 
ATOM   3356 O O   . ILE C 1 151 ? 33.15972 -18.34253 41.06779  1.000 21.89295 ? 151 ILE C O   1 
ATOM   3357 C CB  . ILE C 1 151 ? 32.94796 -16.15159 38.47352  1.000 17.64710 ? 151 ILE C CB  1 
ATOM   3358 C CG1 . ILE C 1 151 ? 32.55097 -14.68117 38.28571  1.000 18.90436 ? 151 ILE C CG1 1 
ATOM   3359 C CG2 . ILE C 1 151 ? 31.73562 -17.08038 38.34057  1.000 21.55259 ? 151 ILE C CG2 1 
ATOM   3360 C CD1 . ILE C 1 151 ? 31.84775 -14.36770 36.96472  1.000 18.10365 ? 151 ILE C CD1 1 
ATOM   3361 N N   . THR C 1 152 ? 34.84325 -18.40107 39.58691  1.000 19.97773 ? 152 THR C N   1 
ATOM   3362 C CA  . THR C 1 152 ? 35.18557 -19.79312 39.84013  1.000 22.04409 ? 152 THR C CA  1 
ATOM   3363 C C   . THR C 1 152 ? 36.59071 -19.88224 40.41392  1.000 23.44924 ? 152 THR C C   1 
ATOM   3364 O O   . THR C 1 152 ? 37.35655 -18.91749 40.40880  1.000 22.08623 ? 152 THR C O   1 
ATOM   3365 C CB  . THR C 1 152 ? 35.09886 -20.62270 38.55765  1.000 24.75747 ? 152 THR C CB  1 
ATOM   3366 O OG1 . THR C 1 152 ? 36.22566 -20.33346 37.72410  1.000 25.54850 ? 152 THR C OG1 1 
ATOM   3367 C CG2 . THR C 1 152 ? 33.82030 -20.31632 37.80217  1.000 25.87893 ? 152 THR C CG2 1 
ATOM   3368 N N   . SER C 1 153 ? 36.93193 -21.06779 40.90663  1.000 22.08350 ? 153 SER C N   1 
ATOM   3369 C CA  . SER C 1 153 ? 38.26227 -21.29413 41.44244  1.000 22.24387 ? 153 SER C CA  1 
ATOM   3370 C C   . SER C 1 153 ? 39.23837 -21.79020 40.38590  1.000 23.67998 ? 153 SER C C   1 
ATOM   3371 O O   . SER C 1 153 ? 40.39048 -22.07513 40.72183  1.000 26.88910 ? 153 SER C O   1 
ATOM   3372 C CB  . SER C 1 153 ? 38.19773 -22.29102 42.60054  1.000 26.69198 ? 153 SER C CB  1 
ATOM   3373 O OG  . SER C 1 153 ? 37.65253 -23.51765 42.15463  1.000 26.41757 ? 153 SER C OG  1 
ATOM   3374 N N   . THR C 1 154 ? 38.80879 -21.89194 39.13000  1.000 24.21131 ? 154 THR C N   1 
ATOM   3375 C CA  . THR C 1 154 ? 39.68778 -22.35586 38.06353  1.000 26.37315 ? 154 THR C CA  1 
ATOM   3376 C C   . THR C 1 154 ? 40.85629 -21.39309 37.88851  1.000 25.34390 ? 154 THR C C   1 
ATOM   3377 O O   . THR C 1 154 ? 40.69853 -20.17303 37.99265  1.000 25.43500 ? 154 THR C O   1 
ATOM   3378 C CB  . THR C 1 154 ? 38.90292 -22.43134 36.75176  1.000 25.81774 ? 154 THR C CB  1 
ATOM   3379 O OG1 . THR C 1 154 ? 37.67018 -23.12763 36.96425  1.000 35.71116 ? 154 THR C OG1 1 
ATOM   3380 C CG2 . THR C 1 154 ? 39.70165 -23.15664 35.67670  1.000 30.89975 ? 154 THR C CG2 1 
ATOM   3381 N N   . SER C 1 155 ? 42.03635 -21.94837 37.62751  1.000 24.75610 ? 155 SER C N   1 
ATOM   3382 C CA  . SER C 1 155 ? 43.22389 -21.16401 37.31969  1.000 24.35871 ? 155 SER C CA  1 
ATOM   3383 C C   . SER C 1 155 ? 43.69610 -21.50628 35.91457  1.000 26.94414 ? 155 SER C C   1 
ATOM   3384 O O   . SER C 1 155 ? 43.43877 -22.60114 35.40826  1.000 28.92780 ? 155 SER C O   1 
ATOM   3385 C CB  . SER C 1 155 ? 44.35053 -21.46571 38.30293  1.000 29.17538 ? 155 SER C CB  1 
ATOM   3386 O OG  . SER C 1 155 ? 44.05248 -20.95006 39.58847  1.000 35.24871 ? 155 SER C OG  1 
ATOM   3387 N N   . HIS C 1 156 ? 44.38774 -20.56420 35.28042  1.000 23.00570 ? 156 HIS C N   1 
ATOM   3388 C CA  . HIS C 1 156 ? 45.00219 -20.79332 33.97962  1.000 19.98229 ? 156 HIS C CA  1 
ATOM   3389 C C   . HIS C 1 156 ? 46.50260 -20.57089 34.11041  1.000 22.58459 ? 156 HIS C C   1 
ATOM   3390 O O   . HIS C 1 156 ? 46.94517 -19.47076 34.45658  1.000 19.91612 ? 156 HIS C O   1 
ATOM   3391 C CB  . HIS C 1 156 ? 44.41536 -19.86527 32.91423  1.000 23.33947 ? 156 HIS C CB  1 
ATOM   3392 C CG  . HIS C 1 156 ? 45.16828 -19.89046 31.61925  1.000 27.98667 ? 156 HIS C CG  1 
ATOM   3393 N ND1 . HIS C 1 156 ? 44.99893 -20.88256 30.67604  1.000 33.12268 ? 156 HIS C ND1 1 
ATOM   3394 C CD2 . HIS C 1 156 ? 46.11473 -19.05802 31.12342  1.000 27.33194 ? 156 HIS C CD2 1 
ATOM   3395 C CE1 . HIS C 1 156 ? 45.79955 -20.65232 29.64945  1.000 29.45745 ? 156 HIS C CE1 1 
ATOM   3396 N NE2 . HIS C 1 156 ? 46.48600 -19.55028 29.89538  1.000 30.46248 ? 156 HIS C NE2 1 
ATOM   3397 N N   . SER C 1 157 ? 47.28036 -21.61391 33.85740  1.000 21.95252 ? 157 SER C N   1 
ATOM   3398 C CA  . SER C 1 157 ? 48.73081 -21.49810 33.82847  1.000 21.60656 ? 157 SER C CA  1 
ATOM   3399 C C   . SER C 1 157 ? 49.11070 -21.02596 32.43064  1.000 23.17877 ? 157 SER C C   1 
ATOM   3400 O O   . SER C 1 157 ? 48.91733 -21.75013 31.44933  1.000 25.85857 ? 157 SER C O   1 
ATOM   3401 C CB  . SER C 1 157 ? 49.37790 -22.83804 34.16594  1.000 23.93610 ? 157 SER C CB  1 
ATOM   3402 O OG  . SER C 1 157 ? 50.78556 -22.71432 34.18993  1.000 32.09898 ? 157 SER C OG  1 
ATOM   3403 N N   . GLY C 1 158 ? 49.61757 -19.80045 32.33229  1.000 19.34907 ? 158 GLY C N   1 
ATOM   3404 C CA  . GLY C 1 158 ? 49.87984 -19.21784 31.03100  1.000 21.35646 ? 158 GLY C CA  1 
ATOM   3405 C C   . GLY C 1 158 ? 51.34646 -18.93920 30.75858  1.000 18.39293 ? 158 GLY C C   1 
ATOM   3406 O O   . GLY C 1 158 ? 52.15880 -18.82320 31.68125  1.000 18.04879 ? 158 GLY C O   1 
ATOM   3407 N N   . SER C 1 159 ? 51.69336 -18.84223 29.48073  1.000 19.72086 ? 159 SER C N   1 
ATOM   3408 C CA  . SER C 1 159 ? 53.05384 -18.49821 29.07411  1.000 18.82945 ? 159 SER C CA  1 
ATOM   3409 C C   . SER C 1 159 ? 52.96421 -17.66143 27.80861  1.000 22.26360 ? 159 SER C C   1 
ATOM   3410 O O   . SER C 1 159 ? 52.33697 -18.08138 26.83018  1.000 27.63536 ? 159 SER C O   1 
ATOM   3411 C CB  . SER C 1 159 ? 53.89327 -19.75456 28.82905  1.000 22.75605 ? 159 SER C CB  1 
ATOM   3412 O OG  . SER C 1 159 ? 55.27143 -19.41862 28.74049  1.000 28.42716 ? 159 SER C OG  1 
ATOM   3413 N N   . VAL C 1 160 ? 53.58217 -16.48271 27.82969  1.000 18.53430 ? 160 VAL C N   1 
ATOM   3414 C CA  . VAL C 1 160 ? 53.49791 -15.52697 26.73354  1.000 18.23243 ? 160 VAL C CA  1 
ATOM   3415 C C   . VAL C 1 160 ? 54.86569 -14.86695 26.58628  1.000 19.11592 ? 160 VAL C C   1 
ATOM   3416 O O   . VAL C 1 160 ? 55.59574 -14.69110 27.56666  1.000 22.90992 ? 160 VAL C O   1 
ATOM   3417 C CB  . VAL C 1 160 ? 52.35147 -14.51690 26.99642  1.000 19.88365 ? 160 VAL C CB  1 
ATOM   3418 C CG1 . VAL C 1 160 ? 52.53048 -13.83242 28.33793  1.000 20.18462 ? 160 VAL C CG1 1 
ATOM   3419 C CG2 . VAL C 1 160 ? 52.21336 -13.51177 25.87573  1.000 22.54797 ? 160 VAL C CG2 1 
ATOM   3420 N N   . THR C 1 161 ? 55.22757 -14.53458 25.34922  1.000 16.37380 ? 161 THR C N   1 
ATOM   3421 C CA  . THR C 1 161 ? 56.57410 -14.07337 25.01918  1.000 14.82202 ? 161 THR C CA  1 
ATOM   3422 C C   . THR C 1 161 ? 56.60891 -12.54974 24.91491  1.000 15.30495 ? 161 THR C C   1 
ATOM   3423 O O   . THR C 1 161 ? 55.70832 -11.93657 24.32967  1.000 15.70842 ? 161 THR C O   1 
ATOM   3424 C CB  . THR C 1 161 ? 57.01678 -14.69221 23.68920  1.000 15.66936 ? 161 THR C CB  1 
ATOM   3425 O OG1 . THR C 1 161 ? 57.04005 -16.12985 23.81218  1.000 19.43511 ? 161 THR C OG1 1 
ATOM   3426 C CG2 . THR C 1 161 ? 58.38380 -14.18972 23.27933  1.000 16.22834 ? 161 THR C CG2 1 
ATOM   3427 N N   . LEU C 1 162 ? 57.66206 -11.95193 25.47890  1.000 13.97298 ? 162 LEU C N   1 
ATOM   3428 C CA  . LEU C 1 162 ? 57.80737 -10.50079 25.47686  1.000 12.77397 ? 162 LEU C CA  1 
ATOM   3429 C C   . LEU C 1 162 ? 58.04181 -9.95912  24.06900  1.000 14.43273 ? 162 LEU C C   1 
ATOM   3430 O O   . LEU C 1 162 ? 58.75008 -10.56106 23.25016  1.000 14.31451 ? 162 LEU C O   1 
ATOM   3431 C CB  . LEU C 1 162 ? 58.95808 -10.06170 26.38102  1.000 14.87762 ? 162 LEU C CB  1 
ATOM   3432 C CG  . LEU C 1 162 ? 58.61053 -9.82998  27.85788  1.000 13.48094 ? 162 LEU C CG  1 
ATOM   3433 C CD1 . LEU C 1 162 ? 58.20354 -11.10702 28.58063  1.000 14.30796 ? 162 LEU C CD1 1 
ATOM   3434 C CD2 . LEU C 1 162 ? 59.78288 -9.15104  28.55755  1.000 14.17522 ? 162 LEU C CD2 1 
ATOM   3435 N N   . VAL C 1 163 ? 57.48342 -8.77786  23.82202  1.000 12.84360 ? 163 VAL C N   1 
ATOM   3436 C CA  . VAL C 1 163 ? 57.55443 -8.08409  22.54254  1.000 14.36043 ? 163 VAL C CA  1 
ATOM   3437 C C   . VAL C 1 163 ? 58.04105 -6.66421  22.80062  1.000 17.52441 ? 163 VAL C C   1 
ATOM   3438 O O   . VAL C 1 163 ? 57.71003 -6.05947  23.82663  1.000 15.13302 ? 163 VAL C O   1 
ATOM   3439 C CB  . VAL C 1 163 ? 56.16808 -8.08052  21.86047  1.000 15.64899 ? 163 VAL C CB  1 
ATOM   3440 C CG1 . VAL C 1 163 ? 56.20097 -7.29509  20.56732  1.000 17.36115 ? 163 VAL C CG1 1 
ATOM   3441 C CG2 . VAL C 1 163 ? 55.71350 -9.50807  21.60190  1.000 15.87528 ? 163 VAL C CG2 1 
ATOM   3442 N N   . ALA C 1 164 ? 58.84854 -6.13396  21.88596  1.000 15.78132 ? 164 ALA C N   1 
ATOM   3443 C CA  . ALA C 1 164 ? 59.28611 -4.75068  22.02090  1.000 14.90694 ? 164 ALA C CA  1 
ATOM   3444 C C   . ALA C 1 164 ? 58.09668 -3.78964  21.92312  1.000 18.09639 ? 164 ALA C C   1 
ATOM   3445 O O   . ALA C 1 164 ? 57.16820 -3.99369  21.13309  1.000 17.73243 ? 164 ALA C O   1 
ATOM   3446 C CB  . ALA C 1 164 ? 60.33174 -4.43791  20.94703  1.000 19.47909 ? 164 ALA C CB  1 
ATOM   3447 N N   . ALA C 1 165 ? 58.11788 -2.74670  22.75120  1.000 16.34007 ? 165 ALA C N   1 
ATOM   3448 C CA  . ALA C 1 165 ? 57.06548 -1.73801  22.69490  1.000 16.70687 ? 165 ALA C CA  1 
ATOM   3449 C C   . ALA C 1 165 ? 57.00765 -1.15537  21.28446  1.000 20.12115 ? 165 ALA C C   1 
ATOM   3450 O O   . ALA C 1 165 ? 58.05075 -1.00125  20.63187  1.000 19.79342 ? 165 ALA C O   1 
ATOM   3451 C CB  . ALA C 1 165 ? 57.34271 -0.61776  23.70077  1.000 17.04697 ? 165 ALA C CB  1 
ATOM   3452 N N   . PRO C 1 166 ? 55.80680 -0.85552  20.76336  1.000 19.71686 ? 166 PRO C N   1 
ATOM   3453 C CA  . PRO C 1 166 ? 55.65984 -0.37920  19.38102  1.000 22.52663 ? 166 PRO C CA  1 
ATOM   3454 C C   . PRO C 1 166 ? 56.25727 0.99942   19.16556  1.000 27.97054 ? 166 PRO C C   1 
ATOM   3455 O O   . PRO C 1 166 ? 56.46437 1.76836   20.11248  1.000 27.98724 ? 166 PRO C O   1 
ATOM   3456 C CB  . PRO C 1 166 ? 54.14084 -0.34137  19.16749  1.000 23.16919 ? 166 PRO C CB  1 
ATOM   3457 C CG  . PRO C 1 166 ? 53.54269 -0.34495  20.53381  1.000 23.18740 ? 166 PRO C CG  1 
ATOM   3458 C CD  . PRO C 1 166 ? 54.51496 -1.05572  21.43588  1.000 18.08115 ? 166 PRO C CD  1 
ATOM   3459 O OXT . PRO C 1 166 ? 56.56297 1.35832   18.02611  1.000 32.42312 ? 166 PRO C OXT 1 
HETATM 3460 N N   . NH4 D 2 .   ? 44.85617 4.74096   26.57791  1.000 8.13910  ? 201 NH4 A N   1 
HETATM 3461 C C1  . GOL E 3 .   ? 49.87035 16.56333  21.76025  1.000 23.67500 ? 202 GOL A C1  1 
HETATM 3462 O O1  . GOL E 3 .   ? 49.41172 16.23066  20.48527  1.000 23.13710 ? 202 GOL A O1  1 
HETATM 3463 C C2  . GOL E 3 .   ? 49.23882 15.54484  22.69492  1.000 20.72711 ? 202 GOL A C2  1 
HETATM 3464 O O2  . GOL E 3 .   ? 49.69254 14.24099  22.40934  1.000 22.36101 ? 202 GOL A O2  1 
HETATM 3465 C C3  . GOL E 3 .   ? 49.61226 16.03427  24.11561  1.000 22.71657 ? 202 GOL A C3  1 
HETATM 3466 O O3  . GOL E 3 .   ? 49.07094 15.13557  25.01997  1.000 21.54127 ? 202 GOL A O3  1 
HETATM 3467 C C1  . CIT F 4 .   ? 30.48602 17.67121  47.35059  1.000 20.50568 ? 201 CIT B C1  1 
HETATM 3468 O O1  . CIT F 4 .   ? 31.39538 16.81167  47.48380  1.000 19.01949 ? 201 CIT B O1  1 
HETATM 3469 O O2  . CIT F 4 .   ? 29.49930 17.66042  48.13488  1.000 22.31119 ? 201 CIT B O2  1 
HETATM 3470 C C2  . CIT F 4 .   ? 30.58081 18.71007  46.25133  1.000 20.23901 ? 201 CIT B C2  1 
HETATM 3471 C C3  . CIT F 4 .   ? 29.76535 19.94698  46.61762  1.000 20.94679 ? 201 CIT B C3  1 
HETATM 3472 O O7  . CIT F 4 .   ? 28.38889 19.54154  46.82383  1.000 24.59174 ? 201 CIT B O7  1 
HETATM 3473 C C4  . CIT F 4 .   ? 29.82994 21.03524  45.54202  1.000 21.88362 ? 201 CIT B C4  1 
HETATM 3474 C C5  . CIT F 4 .   ? 29.10977 20.57759  44.30184  1.000 24.84619 ? 201 CIT B C5  1 
HETATM 3475 O O3  . CIT F 4 .   ? 29.74457 20.04239  43.36615  1.000 26.36975 ? 201 CIT B O3  1 
HETATM 3476 O O4  . CIT F 4 .   ? 27.86810 20.71635  44.19453  1.000 26.56022 ? 201 CIT B O4  1 
HETATM 3477 C C6  . CIT F 4 .   ? 30.32770 20.51380  47.90759  1.000 24.75161 ? 201 CIT B C6  1 
HETATM 3478 O O5  . CIT F 4 .   ? 31.55862 20.73529  48.01319  1.000 23.71119 ? 201 CIT B O5  1 
HETATM 3479 O O6  . CIT F 4 .   ? 29.56873 20.75861  48.87383  1.000 25.40164 ? 201 CIT B O6  1 
HETATM 3480 C C1  . GOL G 3 .   ? 34.15935 7.16627   19.09404  1.000 32.32671 ? 202 GOL B C1  1 
HETATM 3481 O O1  . GOL G 3 .   ? 34.79080 7.48222   17.88626  1.000 26.82797 ? 202 GOL B O1  1 
HETATM 3482 C C2  . GOL G 3 .   ? 35.24536 6.68214   20.03360  1.000 28.34924 ? 202 GOL B C2  1 
HETATM 3483 O O2  . GOL G 3 .   ? 35.99461 7.74267   20.50632  1.000 29.37261 ? 202 GOL B O2  1 
HETATM 3484 C C3  . GOL G 3 .   ? 34.52330 5.89722   21.15350  1.000 28.52917 ? 202 GOL B C3  1 
HETATM 3485 O O3  . GOL G 3 .   ? 35.54136 5.37206   21.96060  1.000 27.50262 ? 202 GOL B O3  1 
HETATM 3486 C C1  . GOL H 3 .   ? 50.58658 -0.02312  18.02515  1.000 27.24144 ? 201 GOL C C1  1 
HETATM 3487 O O1  . GOL H 3 .   ? 50.34957 -0.65464  19.25992  1.000 26.92768 ? 201 GOL C O1  1 
HETATM 3488 C C2  . GOL H 3 .   ? 49.64812 -0.71811  17.04524  1.000 28.12593 ? 201 GOL C C2  1 
HETATM 3489 O O2  . GOL H 3 .   ? 48.40000 -0.14440  17.04294  1.000 28.88861 ? 201 GOL C O2  1 
HETATM 3490 C C3  . GOL H 3 .   ? 50.34946 -0.69266  15.67821  1.000 29.96642 ? 201 GOL C C3  1 
HETATM 3491 O O3  . GOL H 3 .   ? 49.74343 0.29131   14.89636  1.000 25.66651 ? 201 GOL C O3  1 
HETATM 3492 O O   . HOH I 5 .   ? 52.24850 15.03915  52.13902  1.000 30.64249 ? 301 HOH A O   1 
HETATM 3493 O O   . HOH I 5 .   ? 51.42176 16.09805  16.83406  1.000 23.93587 ? 302 HOH A O   1 
HETATM 3494 O O   . HOH I 5 .   ? 46.01076 15.15156  16.36440  1.000 22.87621 ? 303 HOH A O   1 
HETATM 3495 O O   . HOH I 5 .   ? 45.77290 19.44088  52.35829  1.000 23.45778 ? 304 HOH A O   1 
HETATM 3496 O O   . HOH I 5 .   ? 52.67602 19.01822  0.97613   1.000 25.22498 ? 305 HOH A O   1 
HETATM 3497 O O   . HOH I 5 .   ? 39.57699 21.13002  16.49083  1.000 23.91616 ? 306 HOH A O   1 
HETATM 3498 O O   . HOH I 5 .   ? 60.04874 -1.25228  41.13108  1.000 19.59258 ? 307 HOH A O   1 
HETATM 3499 O O   . HOH I 5 .   ? 66.35975 9.79882   41.38666  1.000 19.73607 ? 308 HOH A O   1 
HETATM 3500 O O   . HOH I 5 .   ? 60.13160 -0.00131  47.79505  1.000 28.04708 ? 309 HOH A O   1 
HETATM 3501 O O   . HOH I 5 .   ? 65.54472 11.61771  48.24993  1.000 23.80801 ? 310 HOH A O   1 
HETATM 3502 O O   . HOH I 5 .   ? 42.51384 25.75852  38.41593  1.000 26.19206 ? 311 HOH A O   1 
HETATM 3503 O O   . HOH I 5 .   ? 55.98949 15.82958  -1.50178  1.000 32.49793 ? 312 HOH A O   1 
HETATM 3504 O O   . HOH I 5 .   ? 39.30020 25.97387  48.08598  1.000 33.18815 ? 313 HOH A O   1 
HETATM 3505 O O   . HOH I 5 .   ? 67.91575 2.61275   41.61957  1.000 25.11135 ? 314 HOH A O   1 
HETATM 3506 O O   . HOH I 5 .   ? 38.14123 23.44030  6.10716   1.000 27.61193 ? 315 HOH A O   1 
HETATM 3507 O O   . HOH I 5 .   ? 40.87803 17.73454  15.62058  1.000 21.77757 ? 316 HOH A O   1 
HETATM 3508 O O   . HOH I 5 .   ? 42.68612 21.77367  29.46316  1.000 26.16898 ? 317 HOH A O   1 
HETATM 3509 O O   . HOH I 5 .   ? 37.32724 17.46885  36.23824  1.000 24.43414 ? 318 HOH A O   1 
HETATM 3510 O O   . HOH I 5 .   ? 48.56529 20.44196  27.41550  1.000 26.66444 ? 319 HOH A O   1 
HETATM 3511 O O   . HOH I 5 .   ? 39.69667 22.34271  36.60274  1.000 28.59850 ? 320 HOH A O   1 
HETATM 3512 O O   . HOH I 5 .   ? 32.83080 15.95893  -10.39267 1.000 20.09084 ? 321 HOH A O   1 
HETATM 3513 O O   . HOH I 5 .   ? 62.18695 12.65527  34.98511  1.000 22.09610 ? 322 HOH A O   1 
HETATM 3514 O O   . HOH I 5 .   ? 50.10554 17.55965  27.06615  1.000 25.66926 ? 323 HOH A O   1 
HETATM 3515 O O   . HOH I 5 .   ? 38.99795 19.23879  37.17027  1.000 19.52810 ? 324 HOH A O   1 
HETATM 3516 O O   . HOH I 5 .   ? 60.40038 20.76776  37.92759  1.000 24.26524 ? 325 HOH A O   1 
HETATM 3517 O O   . HOH I 5 .   ? 54.29352 21.21295  46.11791  1.000 18.11608 ? 326 HOH A O   1 
HETATM 3518 O O   . HOH I 5 .   ? 46.34616 26.17002  43.65715  1.000 27.30941 ? 327 HOH A O   1 
HETATM 3519 O O   . HOH I 5 .   ? 52.17797 24.24394  32.87063  1.000 14.58100 ? 328 HOH A O   1 
HETATM 3520 O O   . HOH I 5 .   ? 54.74881 7.86852   17.82289  1.000 20.37071 ? 329 HOH A O   1 
HETATM 3521 O O   . HOH I 5 .   ? 55.72979 13.81372  16.45794  1.000 25.32311 ? 330 HOH A O   1 
HETATM 3522 O O   . HOH I 5 .   ? 42.72302 22.57515  6.04148   1.000 22.43014 ? 331 HOH A O   1 
HETATM 3523 O O   . HOH I 5 .   ? 53.51027 25.88533  43.53296  1.000 24.12077 ? 332 HOH A O   1 
HETATM 3524 O O   . HOH I 5 .   ? 45.01931 27.98405  -7.84026  1.000 24.09907 ? 333 HOH A O   1 
HETATM 3525 O O   . HOH I 5 .   ? 42.40221 16.08789  27.72372  1.000 27.98817 ? 334 HOH A O   1 
HETATM 3526 O O   . HOH I 5 .   ? 33.59927 12.48361  -4.32437  1.000 26.01041 ? 335 HOH A O   1 
HETATM 3527 O O   . HOH I 5 .   ? 36.25484 21.98122  -5.15928  1.000 16.58017 ? 336 HOH A O   1 
HETATM 3528 O O   . HOH I 5 .   ? 52.09910 4.70532   42.73779  1.000 18.38592 ? 337 HOH A O   1 
HETATM 3529 O O   . HOH I 5 .   ? 63.10114 2.63274   46.52106  1.000 17.27088 ? 338 HOH A O   1 
HETATM 3530 O O   . HOH I 5 .   ? 45.94054 21.39042  24.18286  1.000 28.90321 ? 339 HOH A O   1 
HETATM 3531 O O   . HOH I 5 .   ? 44.51494 21.46195  51.04700  1.000 20.54031 ? 340 HOH A O   1 
HETATM 3532 O O   . HOH I 5 .   ? 35.78789 25.83903  -4.93064  1.000 30.00854 ? 341 HOH A O   1 
HETATM 3533 O O   . HOH I 5 .   ? 45.86414 25.48101  49.80197  1.000 26.39979 ? 342 HOH A O   1 
HETATM 3534 O O   . HOH I 5 .   ? 40.80546 12.22429  26.08294  1.000 21.26735 ? 343 HOH A O   1 
HETATM 3535 O O   . HOH I 5 .   ? 35.00188 20.95727  51.79740  1.000 29.32370 ? 344 HOH A O   1 
HETATM 3536 O O   . HOH I 5 .   ? 42.79591 22.70396  32.04129  1.000 19.78374 ? 345 HOH A O   1 
HETATM 3537 O O   . HOH I 5 .   ? 35.38308 23.22431  8.83954   1.000 25.74796 ? 346 HOH A O   1 
HETATM 3538 O O   . HOH I 5 .   ? 51.48446 20.97094  3.17291   1.000 28.03762 ? 347 HOH A O   1 
HETATM 3539 O O   . HOH I 5 .   ? 55.04958 4.08997   50.41285  1.000 29.34399 ? 348 HOH A O   1 
HETATM 3540 O O   . HOH I 5 .   ? 34.81221 17.45030  8.19205   1.000 26.00447 ? 349 HOH A O   1 
HETATM 3541 O O   . HOH I 5 .   ? 54.18959 16.69728  29.68874  1.000 23.80536 ? 350 HOH A O   1 
HETATM 3542 O O   . HOH I 5 .   ? 40.99913 15.04588  50.94348  1.000 24.59614 ? 351 HOH A O   1 
HETATM 3543 O O   . HOH I 5 .   ? 42.13274 7.34037   52.41290  1.000 22.15107 ? 352 HOH A O   1 
HETATM 3544 O O   . HOH I 5 .   ? 50.96609 21.10527  54.50429  1.000 28.27222 ? 353 HOH A O   1 
HETATM 3545 O O   . HOH I 5 .   ? 56.80130 2.19313   50.22150  1.000 32.48882 ? 354 HOH A O   1 
HETATM 3546 O O   . HOH I 5 .   ? 61.22862 14.59282  39.26864  1.000 22.19189 ? 355 HOH A O   1 
HETATM 3547 O O   . HOH I 5 .   ? 53.82824 25.85282  -1.45116  1.000 32.09820 ? 356 HOH A O   1 
HETATM 3548 O O   . HOH I 5 .   ? 66.05000 2.32686   39.70420  1.000 21.42339 ? 357 HOH A O   1 
HETATM 3549 O O   . HOH I 5 .   ? 42.09647 21.27936  8.35787   1.000 19.30452 ? 358 HOH A O   1 
HETATM 3550 O O   . HOH I 5 .   ? 66.21768 12.22438  38.17926  1.000 22.83699 ? 359 HOH A O   1 
HETATM 3551 O O   . HOH I 5 .   ? 31.00097 20.38491  -11.62607 1.000 17.82098 ? 360 HOH A O   1 
HETATM 3552 O O   . HOH I 5 .   ? 62.63738 6.32084   36.11431  1.000 26.30508 ? 361 HOH A O   1 
HETATM 3553 O O   . HOH I 5 .   ? 51.26028 8.15732   23.04633  1.000 15.86753 ? 362 HOH A O   1 
HETATM 3554 O O   . HOH I 5 .   ? 42.78892 25.37540  -0.48101  1.000 23.36367 ? 363 HOH A O   1 
HETATM 3555 O O   . HOH I 5 .   ? 37.37056 27.92636  -8.43483  1.000 18.13240 ? 364 HOH A O   1 
HETATM 3556 O O   . HOH I 5 .   ? 45.94991 22.35272  26.76994  1.000 28.83469 ? 365 HOH A O   1 
HETATM 3557 O O   . HOH I 5 .   ? 45.58836 27.04263  35.21046  1.000 22.79573 ? 366 HOH A O   1 
HETATM 3558 O O   . HOH I 5 .   ? 63.65660 4.15058   35.84396  1.000 24.95135 ? 367 HOH A O   1 
HETATM 3559 O O   . HOH I 5 .   ? 54.84074 17.82658  34.47424  1.000 17.86331 ? 368 HOH A O   1 
HETATM 3560 O O   . HOH I 5 .   ? 62.41225 -6.55628  43.23715  1.000 26.00226 ? 369 HOH A O   1 
HETATM 3561 O O   . HOH I 5 .   ? 46.43846 24.26058  2.68129   1.000 20.29155 ? 370 HOH A O   1 
HETATM 3562 O O   . HOH I 5 .   ? 35.97798 20.03674  4.43326   1.000 20.01391 ? 371 HOH A O   1 
HETATM 3563 O O   . HOH I 5 .   ? 36.41193 22.86775  41.31326  1.000 29.31132 ? 372 HOH A O   1 
HETATM 3564 O O   . HOH I 5 .   ? 53.30251 15.93535  12.69404  1.000 21.53428 ? 373 HOH A O   1 
HETATM 3565 O O   . HOH I 5 .   ? 62.99971 7.97701   51.86287  1.000 30.55594 ? 374 HOH A O   1 
HETATM 3566 O O   . HOH I 5 .   ? 45.16999 8.74068   53.95381  1.000 26.37477 ? 375 HOH A O   1 
HETATM 3567 O O   . HOH I 5 .   ? 49.96018 24.23884  31.07584  1.000 15.90672 ? 376 HOH A O   1 
HETATM 3568 O O   . HOH I 5 .   ? 57.68318 7.74076   41.43689  1.000 25.80714 ? 377 HOH A O   1 
HETATM 3569 O O   . HOH I 5 .   ? 44.58427 26.34556  45.94578  1.000 26.75432 ? 378 HOH A O   1 
HETATM 3570 O O   . HOH I 5 .   ? 55.68652 27.32102  36.73381  1.000 20.49259 ? 379 HOH A O   1 
HETATM 3571 O O   . HOH I 5 .   ? 50.83062 2.50334   38.57944  1.000 23.56356 ? 380 HOH A O   1 
HETATM 3572 O O   . HOH I 5 .   ? 49.83455 18.80280  10.11841  1.000 21.19024 ? 381 HOH A O   1 
HETATM 3573 O O   . HOH I 5 .   ? 42.27540 15.59530  56.84276  1.000 29.48156 ? 382 HOH A O   1 
HETATM 3574 O O   . HOH I 5 .   ? 57.61143 8.79130   14.86212  1.000 30.90714 ? 383 HOH A O   1 
HETATM 3575 O O   . HOH I 5 .   ? 40.58119 23.76990  5.04103   1.000 29.17740 ? 384 HOH A O   1 
HETATM 3576 O O   . HOH I 5 .   ? 44.86514 23.87665  5.03057   1.000 30.84407 ? 385 HOH A O   1 
HETATM 3577 O O   . HOH I 5 .   ? 58.52114 20.28866  35.93100  1.000 20.86473 ? 386 HOH A O   1 
HETATM 3578 O O   . HOH I 5 .   ? 60.43236 16.10768  46.83657  1.000 24.41309 ? 387 HOH A O   1 
HETATM 3579 O O   . HOH I 5 .   ? 46.14765 5.79514   53.59490  1.000 29.54893 ? 388 HOH A O   1 
HETATM 3580 O O   . HOH I 5 .   ? 58.00577 10.48299  28.84057  1.000 31.47936 ? 389 HOH A O   1 
HETATM 3581 O O   . HOH I 5 .   ? 56.15056 10.00034  26.90753  1.000 33.40954 ? 390 HOH A O   1 
HETATM 3582 O O   . HOH I 5 .   ? 52.35056 2.69090   40.66551  1.000 26.39274 ? 391 HOH A O   1 
HETATM 3583 O O   . HOH I 5 .   ? 34.16599 25.66414  0.33607   1.000 33.07072 ? 392 HOH A O   1 
HETATM 3584 O O   . HOH I 5 .   ? 35.81270 25.63575  -7.49857  1.000 26.92697 ? 393 HOH A O   1 
HETATM 3585 O O   . HOH I 5 .   ? 57.78567 17.93779  34.50218  1.000 24.39708 ? 394 HOH A O   1 
HETATM 3586 O O   . HOH I 5 .   ? 63.04272 14.10063  37.09279  1.000 28.75766 ? 395 HOH A O   1 
HETATM 3587 O O   . HOH I 5 .   ? 37.13837 21.53892  37.02918  1.000 29.55228 ? 396 HOH A O   1 
HETATM 3588 O O   . HOH I 5 .   ? 49.84455 23.40802  28.08992  1.000 24.38682 ? 397 HOH A O   1 
HETATM 3589 O O   . HOH I 5 .   ? 54.18658 28.30588  34.67533  1.000 21.69784 ? 398 HOH A O   1 
HETATM 3590 O O   . HOH I 5 .   ? 45.73202 26.60993  32.36275  1.000 26.17744 ? 399 HOH A O   1 
HETATM 3591 O O   . HOH I 5 .   ? 48.58334 26.58451  30.88649  1.000 23.85119 ? 400 HOH A O   1 
HETATM 3592 O O   . HOH I 5 .   ? 43.01146 27.11752  36.12750  1.000 30.65961 ? 401 HOH A O   1 
HETATM 3593 O O   . HOH J 5 .   ? 40.53123 14.82936  25.78122  1.000 29.28652 ? 301 HOH B O   1 
HETATM 3594 O O   . HOH J 5 .   ? 35.71101 8.48734   51.31567  1.000 25.01316 ? 302 HOH B O   1 
HETATM 3595 O O   . HOH J 5 .   ? 33.45375 24.82619  -4.19795  1.000 32.83056 ? 303 HOH B O   1 
HETATM 3596 O O   . HOH J 5 .   ? 29.36139 1.51105   21.16924  1.000 33.15897 ? 304 HOH B O   1 
HETATM 3597 O O   . HOH J 5 .   ? 32.07628 -21.65613 34.68329  1.000 31.68261 ? 305 HOH B O   1 
HETATM 3598 O O   . HOH J 5 .   ? 38.83922 3.10014   10.31964  1.000 23.23835 ? 306 HOH B O   1 
HETATM 3599 O O   . HOH J 5 .   ? 35.70532 -10.22955 27.08548  1.000 26.82017 ? 307 HOH B O   1 
HETATM 3600 O O   . HOH J 5 .   ? 40.57363 26.31835  12.23012  1.000 24.03239 ? 308 HOH B O   1 
HETATM 3601 O O   . HOH J 5 .   ? 42.63406 8.66614   -9.91214  1.000 26.43126 ? 309 HOH B O   1 
HETATM 3602 O O   . HOH J 5 .   ? 32.44333 -13.22435 42.76076  1.000 20.38554 ? 310 HOH B O   1 
HETATM 3603 O O   . HOH J 5 .   ? 38.30980 12.20991  46.25938  1.000 16.07836 ? 311 HOH B O   1 
HETATM 3604 O O   . HOH J 5 .   ? 40.88278 1.89634   39.13518  1.000 26.58970 ? 312 HOH B O   1 
HETATM 3605 O O   . HOH J 5 .   ? 27.03927 3.01847   51.08814  1.000 34.98803 ? 313 HOH B O   1 
HETATM 3606 O O   . HOH J 5 .   ? 33.54060 11.53251  21.03027  1.000 26.82001 ? 314 HOH B O   1 
HETATM 3607 O O   . HOH J 5 .   ? 34.01644 18.68268  12.40221  1.000 20.48429 ? 315 HOH B O   1 
HETATM 3608 O O   . HOH J 5 .   ? 35.11605 18.56724  1.83471   1.000 18.70332 ? 316 HOH B O   1 
HETATM 3609 O O   . HOH J 5 .   ? 36.86409 -12.18481 37.91298  1.000 17.99697 ? 317 HOH B O   1 
HETATM 3610 O O   . HOH J 5 .   ? 30.55033 19.81180  1.17660   1.000 26.37730 ? 318 HOH B O   1 
HETATM 3611 O O   . HOH J 5 .   ? 38.86677 -1.63050  19.80552  1.000 27.61645 ? 319 HOH B O   1 
HETATM 3612 O O   . HOH J 5 .   ? 22.05345 -9.46591  32.35126  1.000 26.19055 ? 320 HOH B O   1 
HETATM 3613 O O   . HOH J 5 .   ? 28.82264 16.25853  52.05242  1.000 18.49587 ? 321 HOH B O   1 
HETATM 3614 O O   . HOH J 5 .   ? 25.78707 -17.63605 41.55191  1.000 22.37178 ? 322 HOH B O   1 
HETATM 3615 O O   . HOH J 5 .   ? 34.60865 14.82519  -12.53034 1.000 21.41958 ? 323 HOH B O   1 
HETATM 3616 O O   . HOH J 5 .   ? 26.93145 -7.64032  47.58416  1.000 21.55766 ? 324 HOH B O   1 
HETATM 3617 O O   . HOH J 5 .   ? 35.53296 14.97477  6.92342   1.000 24.66404 ? 325 HOH B O   1 
HETATM 3618 O O   . HOH J 5 .   ? 22.15523 -8.43205  48.69307  1.000 25.93048 ? 326 HOH B O   1 
HETATM 3619 O O   . HOH J 5 .   ? 30.21255 -15.52434 28.81068  1.000 27.89103 ? 327 HOH B O   1 
HETATM 3620 O O   . HOH J 5 .   ? 21.14313 -12.37475 37.30513  1.000 25.67980 ? 328 HOH B O   1 
HETATM 3621 O O   . HOH J 5 .   ? 33.82930 16.35154  2.56664   1.000 24.81273 ? 329 HOH B O   1 
HETATM 3622 O O   . HOH J 5 .   ? 21.43474 -2.25637  38.13762  1.000 20.63348 ? 330 HOH B O   1 
HETATM 3623 O O   . HOH J 5 .   ? 26.72714 22.45413  45.96837  1.000 29.59493 ? 331 HOH B O   1 
HETATM 3624 O O   . HOH J 5 .   ? 37.07776 16.46107  21.12202  1.000 29.37201 ? 332 HOH B O   1 
HETATM 3625 O O   . HOH J 5 .   ? 33.03400 16.32128  45.34756  1.000 19.21625 ? 333 HOH B O   1 
HETATM 3626 O O   . HOH J 5 .   ? 36.45808 7.54493   0.42550   1.000 24.67488 ? 334 HOH B O   1 
HETATM 3627 O O   . HOH J 5 .   ? 25.49042 -4.21698  45.12179  1.000 21.27605 ? 335 HOH B O   1 
HETATM 3628 O O   . HOH J 5 .   ? 33.89078 1.59045   49.78301  1.000 21.07545 ? 336 HOH B O   1 
HETATM 3629 O O   . HOH J 5 .   ? 32.31724 10.58920  50.04691  1.000 14.66113 ? 337 HOH B O   1 
HETATM 3630 O O   . HOH J 5 .   ? 24.98515 -12.84327 42.35912  1.000 21.29240 ? 338 HOH B O   1 
HETATM 3631 O O   . HOH J 5 .   ? 40.88890 -0.87744  21.40733  1.000 19.72955 ? 339 HOH B O   1 
HETATM 3632 O O   . HOH J 5 .   ? 25.71043 -10.16455 26.40547  1.000 30.26823 ? 340 HOH B O   1 
HETATM 3633 O O   . HOH J 5 .   ? 35.84313 0.70727   17.19903  1.000 32.20002 ? 341 HOH B O   1 
HETATM 3634 O O   . HOH J 5 .   ? 24.71127 -19.28932 37.33025  1.000 21.07765 ? 342 HOH B O   1 
HETATM 3635 O O   . HOH J 5 .   ? 25.06145 -12.52233 39.67384  1.000 18.13026 ? 343 HOH B O   1 
HETATM 3636 O O   . HOH J 5 .   ? 37.23228 -10.28194 46.92759  1.000 21.74319 ? 344 HOH B O   1 
HETATM 3637 O O   . HOH J 5 .   ? 37.48857 -5.50550  48.32665  1.000 24.98541 ? 345 HOH B O   1 
HETATM 3638 O O   . HOH J 5 .   ? 37.12006 2.92480   42.49855  1.000 15.29473 ? 346 HOH B O   1 
HETATM 3639 O O   . HOH J 5 .   ? 40.09018 10.61119  24.10280  1.000 19.99996 ? 347 HOH B O   1 
HETATM 3640 O O   . HOH J 5 .   ? 39.56846 7.47340   57.16310  1.000 29.73748 ? 348 HOH B O   1 
HETATM 3641 O O   . HOH J 5 .   ? 35.89968 11.81066  -5.93821  1.000 19.23208 ? 349 HOH B O   1 
HETATM 3642 O O   . HOH J 5 .   ? 23.59079 -11.12236 43.97293  1.000 18.72210 ? 350 HOH B O   1 
HETATM 3643 O O   . HOH J 5 .   ? 32.49860 20.04216  42.86517  1.000 23.86099 ? 351 HOH B O   1 
HETATM 3644 O O   . HOH J 5 .   ? 39.76312 15.92683  21.36428  1.000 23.66466 ? 352 HOH B O   1 
HETATM 3645 O O   . HOH J 5 .   ? 29.53236 -20.22174 38.72500  1.000 32.43315 ? 353 HOH B O   1 
HETATM 3646 O O   . HOH J 5 .   ? 33.22295 -10.18477 27.30279  1.000 20.95353 ? 354 HOH B O   1 
HETATM 3647 O O   . HOH J 5 .   ? 37.89477 7.58804   13.67038  1.000 21.71597 ? 355 HOH B O   1 
HETATM 3648 O O   . HOH J 5 .   ? 25.32274 12.07938  49.22538  1.000 18.28503 ? 356 HOH B O   1 
HETATM 3649 O O   . HOH J 5 .   ? 34.32933 12.25191  14.54168  1.000 25.60476 ? 357 HOH B O   1 
HETATM 3650 O O   . HOH J 5 .   ? 29.94859 -5.96812  22.28638  1.000 26.27569 ? 358 HOH B O   1 
HETATM 3651 O O   . HOH J 5 .   ? 36.42838 -1.49200  21.61988  1.000 28.29267 ? 359 HOH B O   1 
HETATM 3652 O O   . HOH J 5 .   ? 39.06084 9.65609   -15.54456 1.000 27.96059 ? 360 HOH B O   1 
HETATM 3653 O O   . HOH J 5 .   ? 35.42272 3.68263   51.23728  1.000 22.71809 ? 361 HOH B O   1 
HETATM 3654 O O   . HOH J 5 .   ? 33.87552 11.78734  -1.43410  1.000 22.31910 ? 362 HOH B O   1 
HETATM 3655 O O   . HOH J 5 .   ? 31.69642 6.22818   9.54640   1.000 31.80310 ? 363 HOH B O   1 
HETATM 3656 O O   . HOH J 5 .   ? 35.78304 12.23740  52.63982  1.000 27.32837 ? 364 HOH B O   1 
HETATM 3657 O O   . HOH J 5 .   ? 34.38500 -18.08950 30.12413  1.000 30.39367 ? 365 HOH B O   1 
HETATM 3658 O O   . HOH J 5 .   ? 40.44885 -1.48676  37.40610  1.000 23.15488 ? 366 HOH B O   1 
HETATM 3659 O O   . HOH J 5 .   ? 36.63134 -4.35217  22.78421  1.000 33.21930 ? 367 HOH B O   1 
HETATM 3660 O O   . HOH J 5 .   ? 34.22203 -8.56727  48.09834  1.000 24.92572 ? 368 HOH B O   1 
HETATM 3661 O O   . HOH J 5 .   ? 34.65891 14.14362  21.20358  1.000 24.30907 ? 369 HOH B O   1 
HETATM 3662 O O   . HOH J 5 .   ? 36.15281 -17.77643 33.95342  1.000 24.19793 ? 370 HOH B O   1 
HETATM 3663 O O   . HOH J 5 .   ? 23.30381 10.53154  46.41787  1.000 21.34746 ? 371 HOH B O   1 
HETATM 3664 O O   . HOH J 5 .   ? 46.49638 3.96858   51.84815  1.000 27.93158 ? 372 HOH B O   1 
HETATM 3665 O O   . HOH J 5 .   ? 31.12890 16.37537  54.07228  1.000 23.22851 ? 373 HOH B O   1 
HETATM 3666 O O   . HOH J 5 .   ? 42.15067 4.01287   -1.96879  1.000 24.80166 ? 374 HOH B O   1 
HETATM 3667 O O   . HOH J 5 .   ? 32.38281 9.71844   28.84466  1.000 31.85677 ? 375 HOH B O   1 
HETATM 3668 O O   . HOH J 5 .   ? 40.53350 4.58893   39.45335  1.000 25.12802 ? 376 HOH B O   1 
HETATM 3669 O O   . HOH J 5 .   ? 34.78927 14.58664  13.01231  1.000 17.19111 ? 377 HOH B O   1 
HETATM 3670 O O   . HOH J 5 .   ? 23.94377 -6.77466  23.90623  1.000 27.87957 ? 378 HOH B O   1 
HETATM 3671 O O   . HOH J 5 .   ? 29.31784 -12.65084 47.33623  1.000 32.50126 ? 379 HOH B O   1 
HETATM 3672 O O   . HOH J 5 .   ? 25.08499 -0.45332  22.65495  1.000 28.04717 ? 380 HOH B O   1 
HETATM 3673 O O   . HOH J 5 .   ? 51.37699 10.77983  -14.30804 1.000 31.02381 ? 381 HOH B O   1 
HETATM 3674 O O   . HOH J 5 .   ? 44.64418 4.31369   58.44285  1.000 30.16275 ? 382 HOH B O   1 
HETATM 3675 O O   . HOH J 5 .   ? 34.73686 12.53388  8.40329   1.000 21.29442 ? 383 HOH B O   1 
HETATM 3676 O O   . HOH J 5 .   ? 36.07970 22.80029  4.15596   1.000 26.62579 ? 384 HOH B O   1 
HETATM 3677 O O   . HOH J 5 .   ? 23.64228 0.36433   43.83493  1.000 29.09341 ? 385 HOH B O   1 
HETATM 3678 O O   . HOH J 5 .   ? 32.09751 6.81269   41.52641  1.000 26.53030 ? 386 HOH B O   1 
HETATM 3679 O O   . HOH J 5 .   ? 27.74520 5.07085   29.14730  1.000 29.99625 ? 387 HOH B O   1 
HETATM 3680 O O   . HOH J 5 .   ? 33.97344 12.51721  17.20898  1.000 26.13805 ? 388 HOH B O   1 
HETATM 3681 O O   . HOH J 5 .   ? 39.09874 4.95861   41.72696  1.000 24.05816 ? 389 HOH B O   1 
HETATM 3682 O O   . HOH J 5 .   ? 32.40165 21.36607  51.46949  1.000 33.67713 ? 390 HOH B O   1 
HETATM 3683 O O   . HOH J 5 .   ? 32.13137 8.95513   52.22487  1.000 29.12150 ? 391 HOH B O   1 
HETATM 3684 O O   . HOH J 5 .   ? 28.05963 -19.26547 41.29876  1.000 29.66919 ? 392 HOH B O   1 
HETATM 3685 O O   . HOH J 5 .   ? 25.16403 -5.59905  21.74225  1.000 32.86975 ? 393 HOH B O   1 
HETATM 3686 O O   . HOH K 5 .   ? 70.23812 -12.30171 41.47265  1.000 24.31044 ? 301 HOH C O   1 
HETATM 3687 O O   . HOH K 5 .   ? 58.76949 -15.27337 44.47834  1.000 32.38933 ? 302 HOH C O   1 
HETATM 3688 O O   . HOH K 5 .   ? 57.31425 -16.22955 41.17202  1.000 26.70567 ? 303 HOH C O   1 
HETATM 3689 O O   . HOH K 5 .   ? 54.98889 3.34840   17.68823  1.000 25.72993 ? 304 HOH C O   1 
HETATM 3690 O O   . HOH K 5 .   ? 52.07278 30.18203  -18.25580 1.000 27.29036 ? 305 HOH C O   1 
HETATM 3691 O O   . HOH K 5 .   ? 51.45666 13.53960  -13.44367 1.000 22.28430 ? 306 HOH C O   1 
HETATM 3692 O O   . HOH K 5 .   ? 40.11266 -18.55632 39.90925  1.000 19.24226 ? 307 HOH C O   1 
HETATM 3693 O O   . HOH K 5 .   ? 57.06805 6.00102   18.81434  1.000 30.23386 ? 308 HOH C O   1 
HETATM 3694 O O   . HOH K 5 .   ? 54.51437 16.31485  7.69762   1.000 29.62443 ? 309 HOH C O   1 
HETATM 3695 O O   . HOH K 5 .   ? 40.22697 -11.87744 27.09693  1.000 25.53107 ? 310 HOH C O   1 
HETATM 3696 O O   . HOH K 5 .   ? 40.93249 -18.52264 35.99198  1.000 26.41751 ? 311 HOH C O   1 
HETATM 3697 O O   . HOH K 5 .   ? 39.55831 -15.51898 43.01382  1.000 27.33765 ? 312 HOH C O   1 
HETATM 3698 O O   . HOH K 5 .   ? 40.63194 -2.34575  13.89101  1.000 31.49715 ? 313 HOH C O   1 
HETATM 3699 O O   . HOH K 5 .   ? 64.54388 -12.74092 40.98449  1.000 24.96278 ? 314 HOH C O   1 
HETATM 3700 O O   . HOH K 5 .   ? 50.47915 -15.01991 38.40934  1.000 22.32510 ? 315 HOH C O   1 
HETATM 3701 O O   . HOH K 5 .   ? 60.76632 6.07300   32.79744  1.000 23.34373 ? 316 HOH C O   1 
HETATM 3702 O O   . HOH K 5 .   ? 62.52035 -17.40166 28.38002  1.000 23.36819 ? 317 HOH C O   1 
HETATM 3703 O O   . HOH K 5 .   ? 43.70995 -10.51389 50.38738  1.000 23.27316 ? 318 HOH C O   1 
HETATM 3704 O O   . HOH K 5 .   ? 46.87442 -13.87703 44.34918  1.000 21.34243 ? 319 HOH C O   1 
HETATM 3705 O O   . HOH K 5 .   ? 49.30153 4.80529   12.27613  1.000 18.78179 ? 320 HOH C O   1 
HETATM 3706 O O   . HOH K 5 .   ? 48.99258 -20.78994 43.16484  1.000 34.26315 ? 321 HOH C O   1 
HETATM 3707 O O   . HOH K 5 .   ? 66.59365 -5.60591  27.08316  1.000 25.46450 ? 322 HOH C O   1 
HETATM 3708 O O   . HOH K 5 .   ? 36.88901 -13.80059 29.21118  1.000 30.18986 ? 323 HOH C O   1 
HETATM 3709 O O   . HOH K 5 .   ? 46.96126 -13.23319 49.22188  1.000 28.45650 ? 324 HOH C O   1 
HETATM 3710 O O   . HOH K 5 .   ? 43.59635 -2.42215  11.43746  1.000 26.34671 ? 325 HOH C O   1 
HETATM 3711 O O   . HOH K 5 .   ? 61.91405 2.52570   30.54735  1.000 25.93944 ? 326 HOH C O   1 
HETATM 3712 O O   . HOH K 5 .   ? 48.76992 0.69893   37.08652  1.000 31.94174 ? 327 HOH C O   1 
HETATM 3713 O O   . HOH K 5 .   ? 59.56866 -22.02324 34.34091  1.000 26.24402 ? 328 HOH C O   1 
HETATM 3714 O O   . HOH K 5 .   ? 55.44936 2.44784   22.57910  1.000 25.19441 ? 329 HOH C O   1 
HETATM 3715 O O   . HOH K 5 .   ? 46.55961 -9.62183  23.03411  1.000 28.08415 ? 330 HOH C O   1 
HETATM 3716 O O   . HOH K 5 .   ? 67.86991 -13.37697 35.05191  1.000 22.35835 ? 331 HOH C O   1 
HETATM 3717 O O   . HOH K 5 .   ? 46.15787 -8.69769  38.27916  1.000 17.37263 ? 332 HOH C O   1 
HETATM 3718 O O   . HOH K 5 .   ? 53.29461 10.20423  1.05481   1.000 23.93567 ? 333 HOH C O   1 
HETATM 3719 O O   . HOH K 5 .   ? 60.57982 -0.32674  21.52946  1.000 28.45428 ? 334 HOH C O   1 
HETATM 3720 O O   . HOH K 5 .   ? 52.84787 5.95204   23.54918  1.000 19.03025 ? 335 HOH C O   1 
HETATM 3721 O O   . HOH K 5 .   ? 59.12049 -17.44308 32.50848  1.000 17.68343 ? 336 HOH C O   1 
HETATM 3722 O O   . HOH K 5 .   ? 62.03353 -1.75877  23.11623  1.000 21.78131 ? 337 HOH C O   1 
HETATM 3723 O O   . HOH K 5 .   ? 59.37299 -11.34031 20.65933  1.000 20.06310 ? 338 HOH C O   1 
HETATM 3724 O O   . HOH K 5 .   ? 57.51212 2.78408   24.86077  1.000 29.85204 ? 339 HOH C O   1 
HETATM 3725 O O   . HOH K 5 .   ? 53.37145 9.86905   3.97374   1.000 23.35729 ? 340 HOH C O   1 
HETATM 3726 O O   . HOH K 5 .   ? 59.79683 -7.39900  19.59081  1.000 19.67836 ? 341 HOH C O   1 
HETATM 3727 O O   . HOH K 5 .   ? 53.25260 8.73073   11.95057  1.000 18.47603 ? 342 HOH C O   1 
HETATM 3728 O O   . HOH K 5 .   ? 52.82094 -20.98577 33.36496  1.000 27.80857 ? 343 HOH C O   1 
HETATM 3729 O O   . HOH K 5 .   ? 39.54297 -0.44476  15.25936  1.000 20.33697 ? 344 HOH C O   1 
HETATM 3730 O O   . HOH K 5 .   ? 51.99958 21.62709  -10.54482 1.000 17.03133 ? 345 HOH C O   1 
HETATM 3731 O O   . HOH K 5 .   ? 62.69761 0.08983   30.14260  1.000 19.05453 ? 346 HOH C O   1 
HETATM 3732 O O   . HOH K 5 .   ? 64.78219 -1.46138  27.72651  1.000 25.15511 ? 347 HOH C O   1 
HETATM 3733 O O   . HOH K 5 .   ? 47.77117 28.03273  -6.99269  1.000 28.41677 ? 348 HOH C O   1 
HETATM 3734 O O   . HOH K 5 .   ? 37.10945 6.38287   3.05646   1.000 24.36341 ? 349 HOH C O   1 
HETATM 3735 O O   . HOH K 5 .   ? 66.61591 -11.44335 30.35836  1.000 30.04517 ? 350 HOH C O   1 
HETATM 3736 O O   . HOH K 5 .   ? 65.90206 -11.49246 39.10282  1.000 20.26816 ? 351 HOH C O   1 
HETATM 3737 O O   . HOH K 5 .   ? 51.91680 20.06062  -5.93069  1.000 17.41003 ? 352 HOH C O   1 
HETATM 3738 O O   . HOH K 5 .   ? 53.39934 -14.97498 23.22611  1.000 25.26653 ? 353 HOH C O   1 
HETATM 3739 O O   . HOH K 5 .   ? 43.22766 0.10623   20.23020  1.000 19.44231 ? 354 HOH C O   1 
HETATM 3740 O O   . HOH K 5 .   ? 49.10231 29.65292  -5.29047  1.000 27.67865 ? 355 HOH C O   1 
HETATM 3741 O O   . HOH K 5 .   ? 67.61758 -13.67472 32.48808  1.000 27.00444 ? 356 HOH C O   1 
HETATM 3742 O O   . HOH K 5 .   ? 52.95411 11.85019  -5.82760  1.000 24.82701 ? 357 HOH C O   1 
HETATM 3743 O O   . HOH K 5 .   ? 49.38989 -1.94671  37.17021  1.000 23.01561 ? 358 HOH C O   1 
HETATM 3744 O O   . HOH K 5 .   ? 39.69826 -5.19762  50.04025  1.000 29.47526 ? 359 HOH C O   1 
HETATM 3745 O O   . HOH K 5 .   ? 59.45710 -17.10715 25.05565  1.000 28.99159 ? 360 HOH C O   1 
HETATM 3746 O O   . HOH K 5 .   ? 51.61388 7.93176   -3.52668  1.000 23.96142 ? 361 HOH C O   1 
HETATM 3747 O O   . HOH K 5 .   ? 54.51423 2.30968   7.60563   1.000 30.59969 ? 362 HOH C O   1 
HETATM 3748 O O   . HOH K 5 .   ? 62.15476 -22.19490 36.53910  1.000 19.49526 ? 363 HOH C O   1 
HETATM 3749 O O   . HOH K 5 .   ? 68.41310 -10.94230 32.58255  1.000 29.18108 ? 364 HOH C O   1 
HETATM 3750 O O   . HOH K 5 .   ? 68.12381 2.54124   36.00388  1.000 26.01560 ? 365 HOH C O   1 
HETATM 3751 O O   . HOH K 5 .   ? 48.36990 3.25031   4.78161   1.000 23.40939 ? 366 HOH C O   1 
HETATM 3752 O O   . HOH K 5 .   ? 55.42948 12.07834  1.57927   1.000 25.04745 ? 367 HOH C O   1 
HETATM 3753 O O   . HOH K 5 .   ? 49.46740 22.65925  -16.60982 1.000 25.43994 ? 368 HOH C O   1 
HETATM 3754 O O   . HOH K 5 .   ? 63.99682 -18.20680 40.29889  1.000 24.08023 ? 369 HOH C O   1 
HETATM 3755 O O   . HOH K 5 .   ? 52.84112 -11.13081 23.89851  1.000 23.94405 ? 370 HOH C O   1 
HETATM 3756 O O   . HOH K 5 .   ? 45.16324 0.42284   7.37906   1.000 24.55604 ? 371 HOH C O   1 
HETATM 3757 O O   . HOH K 5 .   ? 54.05789 17.18130  2.62052   1.000 23.90250 ? 372 HOH C O   1 
HETATM 3758 O O   . HOH K 5 .   ? 44.02268 -14.42975 44.84194  1.000 22.89915 ? 373 HOH C O   1 
HETATM 3759 O O   . HOH K 5 .   ? 65.18721 -7.25847  22.91826  1.000 15.50817 ? 374 HOH C O   1 
HETATM 3760 O O   . HOH K 5 .   ? 43.79922 -4.82899  36.22748  1.000 24.56645 ? 375 HOH C O   1 
HETATM 3761 O O   . HOH K 5 .   ? 46.10361 -1.37596  11.36693  1.000 29.54619 ? 376 HOH C O   1 
HETATM 3762 O O   . HOH K 5 .   ? 43.66081 -7.30032  37.47625  1.000 23.89875 ? 377 HOH C O   1 
HETATM 3763 O O   . HOH K 5 .   ? 56.21262 17.01089  -19.67858 1.000 30.52201 ? 378 HOH C O   1 
HETATM 3764 O O   . HOH K 5 .   ? 66.99578 -5.72748  24.43454  1.000 23.67213 ? 379 HOH C O   1 
HETATM 3765 O O   . HOH K 5 .   ? 63.84436 -3.13320  21.59171  1.000 23.89462 ? 380 HOH C O   1 
# 
