data_8UUC
# 
_entry.id   8UUC 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UUC         pdb_00008uuc 10.2210/pdb8uuc/pdb 
WWPDB D_1000275147 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-22 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UUC 
_pdbx_database_status.recvd_initial_deposition_date   2023-11-01 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
4 ssdavid@ucdavis.edu  Sheila David  S 'principal investigator/group leader' 0000-0001-5873-7935 
5 ajfisher@ucdavis.edu Andrew Fisher J 'principal investigator/group leader' 0000-0003-3488-6594 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Trasvina-Arenas, C.H.' 1 0000-0002-9881-375X 
'David, S.S.'           2 0000-0001-5873-7935 
'Fisher, A.J.'          3 0000-0003-3488-6594 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Crystal structure of MutYX: A novel clusterless adenine DNA glycosylase with a distinct C-terminal domain and 8-Oxoguanine recognition sphere.
;
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2025.01.03.631205 
_citation.pdbx_database_id_PubMed   39803464 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Trasvina-Arenas, C.H.' 1 0000-0002-9881-375X 
primary 'Hashemian, M.'         2 ?                   
primary 'Malek, M.'             3 ?                   
primary 'Merrill, S.'           4 ?                   
primary 'Fisher, A.J.'          5 0000-0003-3488-6594 
primary 'David, S.S.'           6 0000-0001-5873-7935 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Adenine DNA glycosylase'                             30645.672 1   ? ? ? ? 
2 polymer     syn 
;DNA (5'-D(*AP*AP*GP*AP*CP*(8OG)P*TP*GP*GP*AP*C)-3')
;
3423.249  1   ? ? ? ? 
3 polymer     syn 
;DNA (5'-D(*TP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*T)-3')
;
3191.073  1   ? ? ? ? 
4 non-polymer syn 'SODIUM ION'                                          22.990    2   ? ? ? ? 
5 non-polymer syn 'MAGNESIUM ION'                                       24.305    2   ? ? ? ? 
6 non-polymer syn 'CHLORIDE ION'                                        35.453    1   ? ? ? ? 
7 non-polymer syn 'PHOSPHATE ION'                                       94.971    1   ? ? ? ? 
8 non-polymer syn 1,2-ETHANEDIOL                                        62.068    12  ? ? ? ? 
9 water       nat water                                                 18.015    269 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no  
;GHMAFVERVRTQGALLYRDLPWRNLDDPYAVLVSEVMLQQTQVVRVGKYWNRFMGMFPTIDALAAASTADVLAQWQGLGY
NRRALALKRTAEVCSAERGGTLPATNEELQALPGIGPATAAGVMAFAYNRPGVYLETNVRTVFLHELFADREKVSDRELW
PLVEATCPEDDARAWYYALLDYGAHLKAVVANPSRRSAHHTRQSTFEGSRRQKRAELVRLVLAEPGIGIDELAERLDAFE
RDAGRKGVDAATFTSIVADLVAEGFFRREGDAFFA
;
;GHMAFVERVRTQGALLYRDLPWRNLDDPYAVLVSEVMLQQTQVVRVGKYWNRFMGMFPTIDALAAASTADVLAQWQGLGY
NRRALALKRTAEVCSAERGGTLPATNEELQALPGIGPATAAGVMAFAYNRPGVYLETNVRTVFLHELFADREKVSDRELW
PLVEATCPEDDARAWYYALLDYGAHLKAVVANPSRRSAHHTRQSTFEGSRRQKRAELVRLVLAEPGIGIDELAERLDAFE
RDAGRKGVDAATFTSIVADLVAEGFFRREGDAFFA
;
A ? 
2 polydeoxyribonucleotide no yes '(DA)(DA)(DG)(DA)(DC)(8OG)(DT)(DG)(DG)(DA)(DC)' AAGACGTGGAC B ? 
3 polydeoxyribonucleotide no yes '(DT)(DG)(DT)(DC)(DC)(DA)(3DR)(DG)(DT)(DC)(DT)' TGTCCANGTCT C ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 'SODIUM ION'    NA  
5 'MAGNESIUM ION' MG  
6 'CHLORIDE ION'  CL  
7 'PHOSPHATE ION' PO4 
8 1,2-ETHANEDIOL  EDO 
9 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLY n 
1 2   HIS n 
1 3   MET n 
1 4   ALA n 
1 5   PHE n 
1 6   VAL n 
1 7   GLU n 
1 8   ARG n 
1 9   VAL n 
1 10  ARG n 
1 11  THR n 
1 12  GLN n 
1 13  GLY n 
1 14  ALA n 
1 15  LEU n 
1 16  LEU n 
1 17  TYR n 
1 18  ARG n 
1 19  ASP n 
1 20  LEU n 
1 21  PRO n 
1 22  TRP n 
1 23  ARG n 
1 24  ASN n 
1 25  LEU n 
1 26  ASP n 
1 27  ASP n 
1 28  PRO n 
1 29  TYR n 
1 30  ALA n 
1 31  VAL n 
1 32  LEU n 
1 33  VAL n 
1 34  SER n 
1 35  GLU n 
1 36  VAL n 
1 37  MET n 
1 38  LEU n 
1 39  GLN n 
1 40  GLN n 
1 41  THR n 
1 42  GLN n 
1 43  VAL n 
1 44  VAL n 
1 45  ARG n 
1 46  VAL n 
1 47  GLY n 
1 48  LYS n 
1 49  TYR n 
1 50  TRP n 
1 51  ASN n 
1 52  ARG n 
1 53  PHE n 
1 54  MET n 
1 55  GLY n 
1 56  MET n 
1 57  PHE n 
1 58  PRO n 
1 59  THR n 
1 60  ILE n 
1 61  ASP n 
1 62  ALA n 
1 63  LEU n 
1 64  ALA n 
1 65  ALA n 
1 66  ALA n 
1 67  SER n 
1 68  THR n 
1 69  ALA n 
1 70  ASP n 
1 71  VAL n 
1 72  LEU n 
1 73  ALA n 
1 74  GLN n 
1 75  TRP n 
1 76  GLN n 
1 77  GLY n 
1 78  LEU n 
1 79  GLY n 
1 80  TYR n 
1 81  ASN n 
1 82  ARG n 
1 83  ARG n 
1 84  ALA n 
1 85  LEU n 
1 86  ALA n 
1 87  LEU n 
1 88  LYS n 
1 89  ARG n 
1 90  THR n 
1 91  ALA n 
1 92  GLU n 
1 93  VAL n 
1 94  CYS n 
1 95  SER n 
1 96  ALA n 
1 97  GLU n 
1 98  ARG n 
1 99  GLY n 
1 100 GLY n 
1 101 THR n 
1 102 LEU n 
1 103 PRO n 
1 104 ALA n 
1 105 THR n 
1 106 ASN n 
1 107 GLU n 
1 108 GLU n 
1 109 LEU n 
1 110 GLN n 
1 111 ALA n 
1 112 LEU n 
1 113 PRO n 
1 114 GLY n 
1 115 ILE n 
1 116 GLY n 
1 117 PRO n 
1 118 ALA n 
1 119 THR n 
1 120 ALA n 
1 121 ALA n 
1 122 GLY n 
1 123 VAL n 
1 124 MET n 
1 125 ALA n 
1 126 PHE n 
1 127 ALA n 
1 128 TYR n 
1 129 ASN n 
1 130 ARG n 
1 131 PRO n 
1 132 GLY n 
1 133 VAL n 
1 134 TYR n 
1 135 LEU n 
1 136 GLU n 
1 137 THR n 
1 138 ASN n 
1 139 VAL n 
1 140 ARG n 
1 141 THR n 
1 142 VAL n 
1 143 PHE n 
1 144 LEU n 
1 145 HIS n 
1 146 GLU n 
1 147 LEU n 
1 148 PHE n 
1 149 ALA n 
1 150 ASP n 
1 151 ARG n 
1 152 GLU n 
1 153 LYS n 
1 154 VAL n 
1 155 SER n 
1 156 ASP n 
1 157 ARG n 
1 158 GLU n 
1 159 LEU n 
1 160 TRP n 
1 161 PRO n 
1 162 LEU n 
1 163 VAL n 
1 164 GLU n 
1 165 ALA n 
1 166 THR n 
1 167 CYS n 
1 168 PRO n 
1 169 GLU n 
1 170 ASP n 
1 171 ASP n 
1 172 ALA n 
1 173 ARG n 
1 174 ALA n 
1 175 TRP n 
1 176 TYR n 
1 177 TYR n 
1 178 ALA n 
1 179 LEU n 
1 180 LEU n 
1 181 ASP n 
1 182 TYR n 
1 183 GLY n 
1 184 ALA n 
1 185 HIS n 
1 186 LEU n 
1 187 LYS n 
1 188 ALA n 
1 189 VAL n 
1 190 VAL n 
1 191 ALA n 
1 192 ASN n 
1 193 PRO n 
1 194 SER n 
1 195 ARG n 
1 196 ARG n 
1 197 SER n 
1 198 ALA n 
1 199 HIS n 
1 200 HIS n 
1 201 THR n 
1 202 ARG n 
1 203 GLN n 
1 204 SER n 
1 205 THR n 
1 206 PHE n 
1 207 GLU n 
1 208 GLY n 
1 209 SER n 
1 210 ARG n 
1 211 ARG n 
1 212 GLN n 
1 213 LYS n 
1 214 ARG n 
1 215 ALA n 
1 216 GLU n 
1 217 LEU n 
1 218 VAL n 
1 219 ARG n 
1 220 LEU n 
1 221 VAL n 
1 222 LEU n 
1 223 ALA n 
1 224 GLU n 
1 225 PRO n 
1 226 GLY n 
1 227 ILE n 
1 228 GLY n 
1 229 ILE n 
1 230 ASP n 
1 231 GLU n 
1 232 LEU n 
1 233 ALA n 
1 234 GLU n 
1 235 ARG n 
1 236 LEU n 
1 237 ASP n 
1 238 ALA n 
1 239 PHE n 
1 240 GLU n 
1 241 ARG n 
1 242 ASP n 
1 243 ALA n 
1 244 GLY n 
1 245 ARG n 
1 246 LYS n 
1 247 GLY n 
1 248 VAL n 
1 249 ASP n 
1 250 ALA n 
1 251 ALA n 
1 252 THR n 
1 253 PHE n 
1 254 THR n 
1 255 SER n 
1 256 ILE n 
1 257 VAL n 
1 258 ALA n 
1 259 ASP n 
1 260 LEU n 
1 261 VAL n 
1 262 ALA n 
1 263 GLU n 
1 264 GLY n 
1 265 PHE n 
1 266 PHE n 
1 267 ARG n 
1 268 ARG n 
1 269 GLU n 
1 270 GLY n 
1 271 ASP n 
1 272 ALA n 
1 273 PHE n 
1 274 PHE n 
1 275 ALA n 
2 1   DA  n 
2 2   DA  n 
2 3   DG  n 
2 4   DA  n 
2 5   DC  n 
2 6   8OG n 
2 7   DT  n 
2 8   DG  n 
2 9   DG  n 
2 10  DA  n 
2 11  DC  n 
3 1   DT  n 
3 2   DG  n 
3 3   DT  n 
3 4   DC  n 
3 5   DC  n 
3 6   DA  n 
3 7   3DR n 
3 8   DG  n 
3 9   DT  n 
3 10  DC  n 
3 11  DT  n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   275 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 MutY 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    YY7918 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Eggerthella sp. YY7918' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     502558 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     511693 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               BL21 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET28 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_pdbx_entity_src_syn.entity_id 
_pdbx_entity_src_syn.pdbx_src_id 
_pdbx_entity_src_syn.pdbx_alt_source_flag 
_pdbx_entity_src_syn.pdbx_beg_seq_num 
_pdbx_entity_src_syn.pdbx_end_seq_num 
_pdbx_entity_src_syn.organism_scientific 
_pdbx_entity_src_syn.organism_common_name 
_pdbx_entity_src_syn.ncbi_taxonomy_id 
_pdbx_entity_src_syn.details 
2 1 sample 1 11 'synthetic construct' ? 32630 ? 
3 1 sample 1 11 'synthetic construct' ? 32630 ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
3DR 'DNA linking'       . "1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE"    'ABASIC DIDEOXYRIBOSE'                                  
'C5 H11 O6 P'     198.111 
8OG 'DNA linking'       n "8-OXO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE" "8-OXO-7,8-DIHYDRO-2'-DEOXY-GUANOSINE-5'-MONOPHOSPHATE" 
'C10 H14 N5 O8 P' 363.221 
ALA 'L-peptide linking' y ALANINE                                     ?                                                       
'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                                    ?                                                       
'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                                  ?                                                       
'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                             ?                                                       
'C4 H7 N O4'      133.103 
CL  non-polymer         . 'CHLORIDE ION'                              ?                                                       
'Cl -1'           35.453  
CYS 'L-peptide linking' y CYSTEINE                                    ?                                                       
'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE"        ?                                                       
'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"         ?                                                       
'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE"        ?                                                       
'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"                ?                                                       
'C10 H15 N2 O8 P' 322.208 
EDO non-polymer         . 1,2-ETHANEDIOL                              'ETHYLENE GLYCOL'                                       
'C2 H6 O2'        62.068  
GLN 'L-peptide linking' y GLUTAMINE                                   ?                                                       
'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                             ?                                                       
'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                                     ?                                                       
'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                                   ?                                                       
'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                       ?                                                       
'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                  ?                                                       
'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                                     ?                                                       
'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                                      ?                                                       
'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                                  ?                                                       
'C5 H11 N O2 S'   149.211 
MG  non-polymer         . 'MAGNESIUM ION'                             ?                                                       
'Mg 2'            24.305  
NA  non-polymer         . 'SODIUM ION'                                ?                                                       
'Na 1'            22.990  
PHE 'L-peptide linking' y PHENYLALANINE                               ?                                                       
'C9 H11 N O2'     165.189 
PO4 non-polymer         . 'PHOSPHATE ION'                             ?                                                       
'O4 P -3'         94.971  
PRO 'L-peptide linking' y PROLINE                                     ?                                                       
'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                                      ?                                                       
'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                                   ?                                                       
'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                  ?                                                       
'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                                    ?                                                       
'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                                      ?                                                       
'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLY 1   -1  ?   ?   ?   A . n 
A 1 2   HIS 2   0   0   HIS HIS A . n 
A 1 3   MET 3   1   1   MET MET A . n 
A 1 4   ALA 4   2   2   ALA ALA A . n 
A 1 5   PHE 5   3   3   PHE PHE A . n 
A 1 6   VAL 6   4   4   VAL VAL A . n 
A 1 7   GLU 7   5   5   GLU GLU A . n 
A 1 8   ARG 8   6   6   ARG ARG A . n 
A 1 9   VAL 9   7   7   VAL VAL A . n 
A 1 10  ARG 10  8   8   ARG ARG A . n 
A 1 11  THR 11  9   9   THR THR A . n 
A 1 12  GLN 12  10  10  GLN GLN A . n 
A 1 13  GLY 13  11  11  GLY GLY A . n 
A 1 14  ALA 14  12  12  ALA ALA A . n 
A 1 15  LEU 15  13  13  LEU LEU A . n 
A 1 16  LEU 16  14  14  LEU LEU A . n 
A 1 17  TYR 17  15  15  TYR TYR A . n 
A 1 18  ARG 18  16  16  ARG ARG A . n 
A 1 19  ASP 19  17  17  ASP ASP A . n 
A 1 20  LEU 20  18  18  LEU LEU A . n 
A 1 21  PRO 21  19  19  PRO PRO A . n 
A 1 22  TRP 22  20  20  TRP TRP A . n 
A 1 23  ARG 23  21  21  ARG ARG A . n 
A 1 24  ASN 24  22  22  ASN ASN A . n 
A 1 25  LEU 25  23  23  LEU LEU A . n 
A 1 26  ASP 26  24  24  ASP ASP A . n 
A 1 27  ASP 27  25  25  ASP ASP A . n 
A 1 28  PRO 28  26  26  PRO PRO A . n 
A 1 29  TYR 29  27  27  TYR TYR A . n 
A 1 30  ALA 30  28  28  ALA ALA A . n 
A 1 31  VAL 31  29  29  VAL VAL A . n 
A 1 32  LEU 32  30  30  LEU LEU A . n 
A 1 33  VAL 33  31  31  VAL VAL A . n 
A 1 34  SER 34  32  32  SER SER A . n 
A 1 35  GLU 35  33  33  GLU GLU A . n 
A 1 36  VAL 36  34  34  VAL VAL A . n 
A 1 37  MET 37  35  35  MET MET A . n 
A 1 38  LEU 38  36  36  LEU LEU A . n 
A 1 39  GLN 39  37  37  GLN GLN A . n 
A 1 40  GLN 40  38  38  GLN GLN A . n 
A 1 41  THR 41  39  39  THR THR A . n 
A 1 42  GLN 42  40  40  GLN GLN A . n 
A 1 43  VAL 43  41  41  VAL VAL A . n 
A 1 44  VAL 44  42  42  VAL VAL A . n 
A 1 45  ARG 45  43  43  ARG ARG A . n 
A 1 46  VAL 46  44  44  VAL VAL A . n 
A 1 47  GLY 47  45  45  GLY GLY A . n 
A 1 48  LYS 48  46  46  LYS LYS A . n 
A 1 49  TYR 49  47  47  TYR TYR A . n 
A 1 50  TRP 50  48  48  TRP TRP A . n 
A 1 51  ASN 51  49  49  ASN ASN A . n 
A 1 52  ARG 52  50  50  ARG ARG A . n 
A 1 53  PHE 53  51  51  PHE PHE A . n 
A 1 54  MET 54  52  52  MET MET A . n 
A 1 55  GLY 55  53  53  GLY GLY A . n 
A 1 56  MET 56  54  54  MET MET A . n 
A 1 57  PHE 57  55  55  PHE PHE A . n 
A 1 58  PRO 58  56  56  PRO PRO A . n 
A 1 59  THR 59  57  57  THR THR A . n 
A 1 60  ILE 60  58  58  ILE ILE A . n 
A 1 61  ASP 61  59  59  ASP ASP A . n 
A 1 62  ALA 62  60  60  ALA ALA A . n 
A 1 63  LEU 63  61  61  LEU LEU A . n 
A 1 64  ALA 64  62  62  ALA ALA A . n 
A 1 65  ALA 65  63  63  ALA ALA A . n 
A 1 66  ALA 66  64  64  ALA ALA A . n 
A 1 67  SER 67  65  65  SER SER A . n 
A 1 68  THR 68  66  66  THR THR A . n 
A 1 69  ALA 69  67  67  ALA ALA A . n 
A 1 70  ASP 70  68  68  ASP ASP A . n 
A 1 71  VAL 71  69  69  VAL VAL A . n 
A 1 72  LEU 72  70  70  LEU LEU A . n 
A 1 73  ALA 73  71  71  ALA ALA A . n 
A 1 74  GLN 74  72  72  GLN GLN A . n 
A 1 75  TRP 75  73  73  TRP TRP A . n 
A 1 76  GLN 76  74  74  GLN GLN A . n 
A 1 77  GLY 77  75  75  GLY GLY A . n 
A 1 78  LEU 78  76  76  LEU LEU A . n 
A 1 79  GLY 79  77  77  GLY GLY A . n 
A 1 80  TYR 80  78  78  TYR TYR A . n 
A 1 81  ASN 81  79  79  ASN ASN A . n 
A 1 82  ARG 82  80  80  ARG ARG A . n 
A 1 83  ARG 83  81  81  ARG ARG A . n 
A 1 84  ALA 84  82  82  ALA ALA A . n 
A 1 85  LEU 85  83  83  LEU LEU A . n 
A 1 86  ALA 86  84  84  ALA ALA A . n 
A 1 87  LEU 87  85  85  LEU LEU A . n 
A 1 88  LYS 88  86  86  LYS LYS A . n 
A 1 89  ARG 89  87  87  ARG ARG A . n 
A 1 90  THR 90  88  88  THR THR A . n 
A 1 91  ALA 91  89  89  ALA ALA A . n 
A 1 92  GLU 92  90  90  GLU GLU A . n 
A 1 93  VAL 93  91  91  VAL VAL A . n 
A 1 94  CYS 94  92  92  CYS CYS A . n 
A 1 95  SER 95  93  93  SER SER A . n 
A 1 96  ALA 96  94  94  ALA ALA A . n 
A 1 97  GLU 97  95  95  GLU GLU A . n 
A 1 98  ARG 98  96  96  ARG ARG A . n 
A 1 99  GLY 99  97  97  GLY GLY A . n 
A 1 100 GLY 100 98  98  GLY GLY A . n 
A 1 101 THR 101 99  99  THR THR A . n 
A 1 102 LEU 102 100 100 LEU LEU A . n 
A 1 103 PRO 103 101 101 PRO PRO A . n 
A 1 104 ALA 104 102 102 ALA ALA A . n 
A 1 105 THR 105 103 103 THR THR A . n 
A 1 106 ASN 106 104 104 ASN ASN A . n 
A 1 107 GLU 107 105 105 GLU GLU A . n 
A 1 108 GLU 108 106 106 GLU GLU A . n 
A 1 109 LEU 109 107 107 LEU LEU A . n 
A 1 110 GLN 110 108 108 GLN GLN A . n 
A 1 111 ALA 111 109 109 ALA ALA A . n 
A 1 112 LEU 112 110 110 LEU LEU A . n 
A 1 113 PRO 113 111 111 PRO PRO A . n 
A 1 114 GLY 114 112 112 GLY GLY A . n 
A 1 115 ILE 115 113 113 ILE ILE A . n 
A 1 116 GLY 116 114 114 GLY GLY A . n 
A 1 117 PRO 117 115 115 PRO PRO A . n 
A 1 118 ALA 118 116 116 ALA ALA A . n 
A 1 119 THR 119 117 117 THR THR A . n 
A 1 120 ALA 120 118 118 ALA ALA A . n 
A 1 121 ALA 121 119 119 ALA ALA A . n 
A 1 122 GLY 122 120 120 GLY GLY A . n 
A 1 123 VAL 123 121 121 VAL VAL A . n 
A 1 124 MET 124 122 122 MET MET A . n 
A 1 125 ALA 125 123 123 ALA ALA A . n 
A 1 126 PHE 126 124 124 PHE PHE A . n 
A 1 127 ALA 127 125 125 ALA ALA A . n 
A 1 128 TYR 128 126 126 TYR TYR A . n 
A 1 129 ASN 129 127 127 ASN ASN A . n 
A 1 130 ARG 130 128 128 ARG ARG A . n 
A 1 131 PRO 131 129 129 PRO PRO A . n 
A 1 132 GLY 132 130 130 GLY GLY A . n 
A 1 133 VAL 133 131 131 VAL VAL A . n 
A 1 134 TYR 134 132 132 TYR TYR A . n 
A 1 135 LEU 135 133 133 LEU LEU A . n 
A 1 136 GLU 136 134 134 GLU GLU A . n 
A 1 137 THR 137 135 135 THR THR A . n 
A 1 138 ASN 138 136 136 ASN ASN A . n 
A 1 139 VAL 139 137 137 VAL VAL A . n 
A 1 140 ARG 140 138 138 ARG ARG A . n 
A 1 141 THR 141 139 139 THR THR A . n 
A 1 142 VAL 142 140 140 VAL VAL A . n 
A 1 143 PHE 143 141 141 PHE PHE A . n 
A 1 144 LEU 144 142 142 LEU LEU A . n 
A 1 145 HIS 145 143 143 HIS HIS A . n 
A 1 146 GLU 146 144 144 GLU GLU A . n 
A 1 147 LEU 147 145 145 LEU LEU A . n 
A 1 148 PHE 148 146 146 PHE PHE A . n 
A 1 149 ALA 149 147 147 ALA ALA A . n 
A 1 150 ASP 150 148 148 ASP ASP A . n 
A 1 151 ARG 151 149 149 ARG ARG A . n 
A 1 152 GLU 152 150 150 GLU GLU A . n 
A 1 153 LYS 153 151 151 LYS LYS A . n 
A 1 154 VAL 154 152 152 VAL VAL A . n 
A 1 155 SER 155 153 153 SER SER A . n 
A 1 156 ASP 156 154 154 ASP ASP A . n 
A 1 157 ARG 157 155 155 ARG ARG A . n 
A 1 158 GLU 158 156 156 GLU GLU A . n 
A 1 159 LEU 159 157 157 LEU LEU A . n 
A 1 160 TRP 160 158 158 TRP TRP A . n 
A 1 161 PRO 161 159 159 PRO PRO A . n 
A 1 162 LEU 162 160 160 LEU LEU A . n 
A 1 163 VAL 163 161 161 VAL VAL A . n 
A 1 164 GLU 164 162 162 GLU GLU A . n 
A 1 165 ALA 165 163 163 ALA ALA A . n 
A 1 166 THR 166 164 164 THR THR A . n 
A 1 167 CYS 167 165 165 CYS CYS A . n 
A 1 168 PRO 168 166 166 PRO PRO A . n 
A 1 169 GLU 169 167 167 GLU GLU A . n 
A 1 170 ASP 170 168 168 ASP ASP A . n 
A 1 171 ASP 171 169 169 ASP ASP A . n 
A 1 172 ALA 172 170 170 ALA ALA A . n 
A 1 173 ARG 173 171 171 ARG ARG A . n 
A 1 174 ALA 174 172 172 ALA ALA A . n 
A 1 175 TRP 175 173 173 TRP TRP A . n 
A 1 176 TYR 176 174 174 TYR TYR A . n 
A 1 177 TYR 177 175 175 TYR TYR A . n 
A 1 178 ALA 178 176 176 ALA ALA A . n 
A 1 179 LEU 179 177 177 LEU LEU A . n 
A 1 180 LEU 180 178 178 LEU LEU A . n 
A 1 181 ASP 181 179 179 ASP ASP A . n 
A 1 182 TYR 182 180 180 TYR TYR A . n 
A 1 183 GLY 183 181 181 GLY GLY A . n 
A 1 184 ALA 184 182 182 ALA ALA A . n 
A 1 185 HIS 185 183 183 HIS HIS A . n 
A 1 186 LEU 186 184 184 LEU LEU A . n 
A 1 187 LYS 187 185 185 LYS LYS A . n 
A 1 188 ALA 188 186 186 ALA ALA A . n 
A 1 189 VAL 189 187 187 VAL VAL A . n 
A 1 190 VAL 190 188 188 VAL VAL A . n 
A 1 191 ALA 191 189 189 ALA ALA A . n 
A 1 192 ASN 192 190 190 ASN ASN A . n 
A 1 193 PRO 193 191 191 PRO PRO A . n 
A 1 194 SER 194 192 192 SER SER A . n 
A 1 195 ARG 195 193 193 ARG ARG A . n 
A 1 196 ARG 196 194 194 ARG ARG A . n 
A 1 197 SER 197 195 195 SER SER A . n 
A 1 198 ALA 198 196 196 ALA ALA A . n 
A 1 199 HIS 199 197 197 HIS HIS A . n 
A 1 200 HIS 200 198 198 HIS HIS A . n 
A 1 201 THR 201 199 199 THR THR A . n 
A 1 202 ARG 202 200 200 ARG ARG A . n 
A 1 203 GLN 203 201 201 GLN GLN A . n 
A 1 204 SER 204 202 202 SER SER A . n 
A 1 205 THR 205 203 203 THR THR A . n 
A 1 206 PHE 206 204 204 PHE PHE A . n 
A 1 207 GLU 207 205 205 GLU GLU A . n 
A 1 208 GLY 208 206 206 GLY GLY A . n 
A 1 209 SER 209 207 207 SER SER A . n 
A 1 210 ARG 210 208 208 ARG ARG A . n 
A 1 211 ARG 211 209 209 ARG ARG A . n 
A 1 212 GLN 212 210 210 GLN GLN A . n 
A 1 213 LYS 213 211 211 LYS LYS A . n 
A 1 214 ARG 214 212 212 ARG ARG A . n 
A 1 215 ALA 215 213 213 ALA ALA A . n 
A 1 216 GLU 216 214 214 GLU GLU A . n 
A 1 217 LEU 217 215 215 LEU LEU A . n 
A 1 218 VAL 218 216 216 VAL VAL A . n 
A 1 219 ARG 219 217 217 ARG ARG A . n 
A 1 220 LEU 220 218 218 LEU LEU A . n 
A 1 221 VAL 221 219 219 VAL VAL A . n 
A 1 222 LEU 222 220 220 LEU LEU A . n 
A 1 223 ALA 223 221 221 ALA ALA A . n 
A 1 224 GLU 224 222 222 GLU GLU A . n 
A 1 225 PRO 225 223 223 PRO PRO A . n 
A 1 226 GLY 226 224 224 GLY GLY A . n 
A 1 227 ILE 227 225 225 ILE ILE A . n 
A 1 228 GLY 228 226 226 GLY GLY A . n 
A 1 229 ILE 229 227 227 ILE ILE A . n 
A 1 230 ASP 230 228 228 ASP ASP A . n 
A 1 231 GLU 231 229 229 GLU GLU A . n 
A 1 232 LEU 232 230 230 LEU LEU A . n 
A 1 233 ALA 233 231 231 ALA ALA A . n 
A 1 234 GLU 234 232 232 GLU GLU A . n 
A 1 235 ARG 235 233 233 ARG ARG A . n 
A 1 236 LEU 236 234 234 LEU LEU A . n 
A 1 237 ASP 237 235 235 ASP ASP A . n 
A 1 238 ALA 238 236 236 ALA ALA A . n 
A 1 239 PHE 239 237 237 PHE PHE A . n 
A 1 240 GLU 240 238 238 GLU GLU A . n 
A 1 241 ARG 241 239 239 ARG ARG A . n 
A 1 242 ASP 242 240 240 ASP ASP A . n 
A 1 243 ALA 243 241 241 ALA ALA A . n 
A 1 244 GLY 244 242 242 GLY GLY A . n 
A 1 245 ARG 245 243 243 ARG ARG A . n 
A 1 246 LYS 246 244 244 LYS LYS A . n 
A 1 247 GLY 247 245 245 GLY GLY A . n 
A 1 248 VAL 248 246 246 VAL VAL A . n 
A 1 249 ASP 249 247 247 ASP ASP A . n 
A 1 250 ALA 250 248 248 ALA ALA A . n 
A 1 251 ALA 251 249 249 ALA ALA A . n 
A 1 252 THR 252 250 250 THR THR A . n 
A 1 253 PHE 253 251 251 PHE PHE A . n 
A 1 254 THR 254 252 252 THR THR A . n 
A 1 255 SER 255 253 253 SER SER A . n 
A 1 256 ILE 256 254 254 ILE ILE A . n 
A 1 257 VAL 257 255 255 VAL VAL A . n 
A 1 258 ALA 258 256 256 ALA ALA A . n 
A 1 259 ASP 259 257 257 ASP ASP A . n 
A 1 260 LEU 260 258 258 LEU LEU A . n 
A 1 261 VAL 261 259 259 VAL VAL A . n 
A 1 262 ALA 262 260 260 ALA ALA A . n 
A 1 263 GLU 263 261 261 GLU GLU A . n 
A 1 264 GLY 264 262 262 GLY GLY A . n 
A 1 265 PHE 265 263 263 PHE PHE A . n 
A 1 266 PHE 266 264 264 PHE PHE A . n 
A 1 267 ARG 267 265 265 ARG ARG A . n 
A 1 268 ARG 268 266 266 ARG ARG A . n 
A 1 269 GLU 269 267 267 GLU GLU A . n 
A 1 270 GLY 270 268 268 GLY GLY A . n 
A 1 271 ASP 271 269 269 ASP ASP A . n 
A 1 272 ALA 272 270 270 ALA ALA A . n 
A 1 273 PHE 273 271 271 PHE PHE A . n 
A 1 274 PHE 274 272 272 PHE PHE A . n 
A 1 275 ALA 275 273 273 ALA ALA A . n 
B 2 1   DA  1   1   1   DA  DA  B . n 
B 2 2   DA  2   2   2   DA  DA  B . n 
B 2 3   DG  3   3   3   DG  DG  B . n 
B 2 4   DA  4   4   4   DA  DA  B . n 
B 2 5   DC  5   5   5   DC  DC  B . n 
B 2 6   8OG 6   6   6   8OG 8OG B . n 
B 2 7   DT  7   7   7   DT  DT  B . n 
B 2 8   DG  8   8   8   DG  DG  B . n 
B 2 9   DG  9   9   9   DG  DG  B . n 
B 2 10  DA  10  10  10  DA  DA  B . n 
B 2 11  DC  11  11  11  DC  DC  B . n 
C 3 1   DT  1   1   1   DT  DT  C . n 
C 3 2   DG  2   2   2   DG  DG  C . n 
C 3 3   DT  3   3   3   DT  DT  C . n 
C 3 4   DC  4   4   4   DC  DC  C . n 
C 3 5   DC  5   5   5   DC  DC  C . n 
C 3 6   DA  6   6   6   DA  DA  C . n 
C 3 7   3DR 7   7   7   3DR 3DR C . n 
C 3 8   DG  8   8   8   DG  DG  C . n 
C 3 9   DT  9   9   9   DT  DT  C . n 
C 3 10  DC  10  10  10  DC  DC  C . n 
C 3 11  DT  11  11  11  DT  DT  C . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 NA  1   301 1   NA  NA  A . 
E 4 NA  1   302 2   NA  NA  A . 
F 5 MG  1   303 4   MG  MG  A . 
G 6 CL  1   304 5   CL  CL  A . 
H 7 PO4 1   305 6   PO4 PO4 A . 
I 8 EDO 1   306 7   EDO EDO A . 
J 8 EDO 1   307 8   EDO EDO A . 
K 8 EDO 1   308 9   EDO EDO A . 
L 8 EDO 1   309 1   EDO EDO A . 
M 8 EDO 1   310 1   EDO EDO A . 
N 8 EDO 1   311 1   EDO EDO A . 
O 8 EDO 1   312 1   EDO EDO A . 
P 8 EDO 1   313 1   EDO EDO A . 
Q 8 EDO 1   314 1   EDO EDO A . 
R 8 EDO 1   315 1   EDO EDO A . 
S 8 EDO 1   316 1   EDO EDO A . 
T 5 MG  1   101 3   MG  MG  B . 
U 8 EDO 1   101 1   EDO EDO C . 
V 9 HOH 1   401 311 HOH HOH A . 
V 9 HOH 2   402 215 HOH HOH A . 
V 9 HOH 3   403 106 HOH HOH A . 
V 9 HOH 4   404 236 HOH HOH A . 
V 9 HOH 5   405 30  HOH HOH A . 
V 9 HOH 6   406 185 HOH HOH A . 
V 9 HOH 7   407 306 HOH HOH A . 
V 9 HOH 8   408 187 HOH HOH A . 
V 9 HOH 9   409 36  HOH HOH A . 
V 9 HOH 10  410 161 HOH HOH A . 
V 9 HOH 11  411 7   HOH HOH A . 
V 9 HOH 12  412 89  HOH HOH A . 
V 9 HOH 13  413 23  HOH HOH A . 
V 9 HOH 14  414 3   HOH HOH A . 
V 9 HOH 15  415 59  HOH HOH A . 
V 9 HOH 16  416 127 HOH HOH A . 
V 9 HOH 17  417 4   HOH HOH A . 
V 9 HOH 18  418 159 HOH HOH A . 
V 9 HOH 19  419 102 HOH HOH A . 
V 9 HOH 20  420 189 HOH HOH A . 
V 9 HOH 21  421 6   HOH HOH A . 
V 9 HOH 22  422 323 HOH HOH A . 
V 9 HOH 23  423 216 HOH HOH A . 
V 9 HOH 24  424 144 HOH HOH A . 
V 9 HOH 25  425 45  HOH HOH A . 
V 9 HOH 26  426 49  HOH HOH A . 
V 9 HOH 27  427 19  HOH HOH A . 
V 9 HOH 28  428 100 HOH HOH A . 
V 9 HOH 29  429 128 HOH HOH A . 
V 9 HOH 30  430 176 HOH HOH A . 
V 9 HOH 31  431 136 HOH HOH A . 
V 9 HOH 32  432 46  HOH HOH A . 
V 9 HOH 33  433 150 HOH HOH A . 
V 9 HOH 34  434 104 HOH HOH A . 
V 9 HOH 35  435 11  HOH HOH A . 
V 9 HOH 36  436 8   HOH HOH A . 
V 9 HOH 37  437 137 HOH HOH A . 
V 9 HOH 38  438 24  HOH HOH A . 
V 9 HOH 39  439 50  HOH HOH A . 
V 9 HOH 40  440 140 HOH HOH A . 
V 9 HOH 41  441 188 HOH HOH A . 
V 9 HOH 42  442 42  HOH HOH A . 
V 9 HOH 43  443 10  HOH HOH A . 
V 9 HOH 44  444 37  HOH HOH A . 
V 9 HOH 45  445 213 HOH HOH A . 
V 9 HOH 46  446 58  HOH HOH A . 
V 9 HOH 47  447 82  HOH HOH A . 
V 9 HOH 48  448 206 HOH HOH A . 
V 9 HOH 49  449 12  HOH HOH A . 
V 9 HOH 50  450 54  HOH HOH A . 
V 9 HOH 51  451 151 HOH HOH A . 
V 9 HOH 52  452 101 HOH HOH A . 
V 9 HOH 53  453 81  HOH HOH A . 
V 9 HOH 54  454 99  HOH HOH A . 
V 9 HOH 55  455 146 HOH HOH A . 
V 9 HOH 56  456 158 HOH HOH A . 
V 9 HOH 57  457 96  HOH HOH A . 
V 9 HOH 58  458 1   HOH HOH A . 
V 9 HOH 59  459 64  HOH HOH A . 
V 9 HOH 60  460 233 HOH HOH A . 
V 9 HOH 61  461 47  HOH HOH A . 
V 9 HOH 62  462 301 HOH HOH A . 
V 9 HOH 63  463 32  HOH HOH A . 
V 9 HOH 64  464 292 HOH HOH A . 
V 9 HOH 65  465 63  HOH HOH A . 
V 9 HOH 66  466 21  HOH HOH A . 
V 9 HOH 67  467 318 HOH HOH A . 
V 9 HOH 68  468 16  HOH HOH A . 
V 9 HOH 69  469 170 HOH HOH A . 
V 9 HOH 70  470 320 HOH HOH A . 
V 9 HOH 71  471 194 HOH HOH A . 
V 9 HOH 72  472 269 HOH HOH A . 
V 9 HOH 73  473 57  HOH HOH A . 
V 9 HOH 74  474 86  HOH HOH A . 
V 9 HOH 75  475 108 HOH HOH A . 
V 9 HOH 76  476 165 HOH HOH A . 
V 9 HOH 77  477 65  HOH HOH A . 
V 9 HOH 78  478 115 HOH HOH A . 
V 9 HOH 79  479 71  HOH HOH A . 
V 9 HOH 80  480 33  HOH HOH A . 
V 9 HOH 81  481 38  HOH HOH A . 
V 9 HOH 82  482 135 HOH HOH A . 
V 9 HOH 83  483 67  HOH HOH A . 
V 9 HOH 84  484 79  HOH HOH A . 
V 9 HOH 85  485 171 HOH HOH A . 
V 9 HOH 86  486 9   HOH HOH A . 
V 9 HOH 87  487 48  HOH HOH A . 
V 9 HOH 88  488 109 HOH HOH A . 
V 9 HOH 89  489 52  HOH HOH A . 
V 9 HOH 90  490 210 HOH HOH A . 
V 9 HOH 91  491 229 HOH HOH A . 
V 9 HOH 92  492 78  HOH HOH A . 
V 9 HOH 93  493 77  HOH HOH A . 
V 9 HOH 94  494 131 HOH HOH A . 
V 9 HOH 95  495 39  HOH HOH A . 
V 9 HOH 96  496 191 HOH HOH A . 
V 9 HOH 97  497 232 HOH HOH A . 
V 9 HOH 98  498 27  HOH HOH A . 
V 9 HOH 99  499 103 HOH HOH A . 
V 9 HOH 100 500 179 HOH HOH A . 
V 9 HOH 101 501 124 HOH HOH A . 
V 9 HOH 102 502 251 HOH HOH A . 
V 9 HOH 103 503 13  HOH HOH A . 
V 9 HOH 104 504 178 HOH HOH A . 
V 9 HOH 105 505 155 HOH HOH A . 
V 9 HOH 106 506 166 HOH HOH A . 
V 9 HOH 107 507 242 HOH HOH A . 
V 9 HOH 108 508 152 HOH HOH A . 
V 9 HOH 109 509 256 HOH HOH A . 
V 9 HOH 110 510 14  HOH HOH A . 
V 9 HOH 111 511 17  HOH HOH A . 
V 9 HOH 112 512 130 HOH HOH A . 
V 9 HOH 113 513 223 HOH HOH A . 
V 9 HOH 114 514 69  HOH HOH A . 
V 9 HOH 115 515 105 HOH HOH A . 
V 9 HOH 116 516 153 HOH HOH A . 
V 9 HOH 117 517 142 HOH HOH A . 
V 9 HOH 118 518 87  HOH HOH A . 
V 9 HOH 119 519 70  HOH HOH A . 
V 9 HOH 120 520 40  HOH HOH A . 
V 9 HOH 121 521 180 HOH HOH A . 
V 9 HOH 122 522 319 HOH HOH A . 
V 9 HOH 123 523 25  HOH HOH A . 
V 9 HOH 124 524 212 HOH HOH A . 
V 9 HOH 125 525 92  HOH HOH A . 
V 9 HOH 126 526 147 HOH HOH A . 
V 9 HOH 127 527 234 HOH HOH A . 
V 9 HOH 128 528 243 HOH HOH A . 
V 9 HOH 129 529 173 HOH HOH A . 
V 9 HOH 130 530 184 HOH HOH A . 
V 9 HOH 131 531 88  HOH HOH A . 
V 9 HOH 132 532 62  HOH HOH A . 
V 9 HOH 133 533 98  HOH HOH A . 
V 9 HOH 134 534 237 HOH HOH A . 
V 9 HOH 135 535 34  HOH HOH A . 
V 9 HOH 136 536 169 HOH HOH A . 
V 9 HOH 137 537 138 HOH HOH A . 
V 9 HOH 138 538 246 HOH HOH A . 
V 9 HOH 139 539 75  HOH HOH A . 
V 9 HOH 140 540 276 HOH HOH A . 
V 9 HOH 141 541 41  HOH HOH A . 
V 9 HOH 142 542 288 HOH HOH A . 
V 9 HOH 143 543 133 HOH HOH A . 
V 9 HOH 144 544 264 HOH HOH A . 
V 9 HOH 145 545 145 HOH HOH A . 
V 9 HOH 146 546 174 HOH HOH A . 
V 9 HOH 147 547 208 HOH HOH A . 
V 9 HOH 148 548 97  HOH HOH A . 
V 9 HOH 149 549 235 HOH HOH A . 
V 9 HOH 150 550 312 HOH HOH A . 
V 9 HOH 151 551 182 HOH HOH A . 
V 9 HOH 152 552 228 HOH HOH A . 
V 9 HOH 153 553 118 HOH HOH A . 
V 9 HOH 154 554 181 HOH HOH A . 
V 9 HOH 155 555 214 HOH HOH A . 
V 9 HOH 156 556 283 HOH HOH A . 
V 9 HOH 157 557 290 HOH HOH A . 
V 9 HOH 158 558 325 HOH HOH A . 
V 9 HOH 159 559 55  HOH HOH A . 
V 9 HOH 160 560 116 HOH HOH A . 
V 9 HOH 161 561 163 HOH HOH A . 
V 9 HOH 162 562 303 HOH HOH A . 
V 9 HOH 163 563 226 HOH HOH A . 
V 9 HOH 164 564 205 HOH HOH A . 
V 9 HOH 165 565 168 HOH HOH A . 
V 9 HOH 166 566 164 HOH HOH A . 
V 9 HOH 167 567 302 HOH HOH A . 
V 9 HOH 168 568 197 HOH HOH A . 
V 9 HOH 169 569 177 HOH HOH A . 
V 9 HOH 170 570 126 HOH HOH A . 
V 9 HOH 171 571 196 HOH HOH A . 
V 9 HOH 172 572 294 HOH HOH A . 
V 9 HOH 173 573 162 HOH HOH A . 
V 9 HOH 174 574 277 HOH HOH A . 
V 9 HOH 175 575 167 HOH HOH A . 
V 9 HOH 176 576 111 HOH HOH A . 
V 9 HOH 177 577 272 HOH HOH A . 
V 9 HOH 178 578 120 HOH HOH A . 
V 9 HOH 179 579 119 HOH HOH A . 
V 9 HOH 180 580 68  HOH HOH A . 
V 9 HOH 181 581 157 HOH HOH A . 
V 9 HOH 182 582 287 HOH HOH A . 
V 9 HOH 183 583 94  HOH HOH A . 
V 9 HOH 184 584 211 HOH HOH A . 
V 9 HOH 185 585 322 HOH HOH A . 
V 9 HOH 186 586 281 HOH HOH A . 
V 9 HOH 187 587 114 HOH HOH A . 
V 9 HOH 188 588 275 HOH HOH A . 
V 9 HOH 189 589 107 HOH HOH A . 
V 9 HOH 190 590 134 HOH HOH A . 
V 9 HOH 191 591 321 HOH HOH A . 
V 9 HOH 192 592 132 HOH HOH A . 
V 9 HOH 193 593 225 HOH HOH A . 
V 9 HOH 194 594 201 HOH HOH A . 
V 9 HOH 195 595 239 HOH HOH A . 
V 9 HOH 196 596 195 HOH HOH A . 
V 9 HOH 197 597 324 HOH HOH A . 
W 9 HOH 1   201 300 HOH HOH B . 
W 9 HOH 2   202 305 HOH HOH B . 
W 9 HOH 3   203 199 HOH HOH B . 
W 9 HOH 4   204 85  HOH HOH B . 
W 9 HOH 5   205 307 HOH HOH B . 
W 9 HOH 6   206 18  HOH HOH B . 
W 9 HOH 7   207 154 HOH HOH B . 
W 9 HOH 8   208 44  HOH HOH B . 
W 9 HOH 9   209 125 HOH HOH B . 
W 9 HOH 10  210 84  HOH HOH B . 
W 9 HOH 11  211 20  HOH HOH B . 
W 9 HOH 12  212 129 HOH HOH B . 
W 9 HOH 13  213 76  HOH HOH B . 
W 9 HOH 14  214 141 HOH HOH B . 
W 9 HOH 15  215 91  HOH HOH B . 
W 9 HOH 16  216 93  HOH HOH B . 
W 9 HOH 17  217 35  HOH HOH B . 
W 9 HOH 18  218 83  HOH HOH B . 
W 9 HOH 19  219 156 HOH HOH B . 
W 9 HOH 20  220 160 HOH HOH B . 
W 9 HOH 21  221 90  HOH HOH B . 
W 9 HOH 22  222 266 HOH HOH B . 
W 9 HOH 23  223 143 HOH HOH B . 
W 9 HOH 24  224 192 HOH HOH B . 
W 9 HOH 25  225 172 HOH HOH B . 
W 9 HOH 26  226 190 HOH HOH B . 
W 9 HOH 27  227 74  HOH HOH B . 
W 9 HOH 28  228 267 HOH HOH B . 
W 9 HOH 29  229 80  HOH HOH B . 
W 9 HOH 30  230 121 HOH HOH B . 
W 9 HOH 31  231 265 HOH HOH B . 
W 9 HOH 32  232 254 HOH HOH B . 
X 9 HOH 1   201 299 HOH HOH C . 
X 9 HOH 2   202 149 HOH HOH C . 
X 9 HOH 3   203 309 HOH HOH C . 
X 9 HOH 4   204 112 HOH HOH C . 
X 9 HOH 5   205 286 HOH HOH C . 
X 9 HOH 6   206 241 HOH HOH C . 
X 9 HOH 7   207 110 HOH HOH C . 
X 9 HOH 8   208 26  HOH HOH C . 
X 9 HOH 9   209 117 HOH HOH C . 
X 9 HOH 10  210 29  HOH HOH C . 
X 9 HOH 11  211 95  HOH HOH C . 
X 9 HOH 12  212 56  HOH HOH C . 
X 9 HOH 13  213 122 HOH HOH C . 
X 9 HOH 14  214 43  HOH HOH C . 
X 9 HOH 15  215 15  HOH HOH C . 
X 9 HOH 16  216 28  HOH HOH C . 
X 9 HOH 17  217 2   HOH HOH C . 
X 9 HOH 18  218 5   HOH HOH C . 
X 9 HOH 19  219 31  HOH HOH C . 
X 9 HOH 20  220 244 HOH HOH C . 
X 9 HOH 21  221 249 HOH HOH C . 
X 9 HOH 22  222 61  HOH HOH C . 
X 9 HOH 23  223 222 HOH HOH C . 
X 9 HOH 24  224 247 HOH HOH C . 
X 9 HOH 25  225 53  HOH HOH C . 
X 9 HOH 26  226 60  HOH HOH C . 
X 9 HOH 27  227 217 HOH HOH C . 
X 9 HOH 28  228 148 HOH HOH C . 
X 9 HOH 29  229 219 HOH HOH C . 
X 9 HOH 30  230 66  HOH HOH C . 
X 9 HOH 31  231 72  HOH HOH C . 
X 9 HOH 32  232 245 HOH HOH C . 
X 9 HOH 33  233 218 HOH HOH C . 
X 9 HOH 34  234 304 HOH HOH C . 
X 9 HOH 35  235 73  HOH HOH C . 
X 9 HOH 36  236 207 HOH HOH C . 
X 9 HOH 37  237 203 HOH HOH C . 
X 9 HOH 38  238 123 HOH HOH C . 
X 9 HOH 39  239 113 HOH HOH C . 
X 9 HOH 40  240 22  HOH HOH C . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 105 ? CG  ? A GLU 107 CG  
2  1 Y 1 A GLU 105 ? CD  ? A GLU 107 CD  
3  1 Y 1 A GLU 105 ? OE1 ? A GLU 107 OE1 
4  1 Y 1 A GLU 105 ? OE2 ? A GLU 107 OE2 
5  1 Y 1 A ARG 128 ? NE  ? A ARG 130 NE  
6  1 Y 1 A ARG 128 ? CZ  ? A ARG 130 CZ  
7  1 Y 1 A ARG 128 ? NH1 ? A ARG 130 NH1 
8  1 Y 1 A ARG 128 ? NH2 ? A ARG 130 NH2 
9  1 Y 1 A ASP 148 ? CG  ? A ASP 150 CG  
10 1 Y 1 A ASP 148 ? OD1 ? A ASP 150 OD1 
11 1 Y 1 A ASP 148 ? OD2 ? A ASP 150 OD2 
12 1 Y 1 A GLU 167 ? OE2 ? A GLU 169 OE2 
13 1 Y 1 A LYS 244 ? CG  ? A LYS 246 CG  
14 1 Y 1 A LYS 244 ? CD  ? A LYS 246 CD  
15 1 Y 1 A LYS 244 ? CE  ? A LYS 246 CE  
16 1 Y 1 A LYS 244 ? NZ  ? A LYS 246 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.20.1_4487 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UUC 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     38.832 
_cell.length_a_esd                 ? 
_cell.length_b                     84.137 
_cell.length_b_esd                 ? 
_cell.length_c                     225.742 
_cell.length_c_esd                 ? 
_cell.volume                       737546.065 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UUC 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            'C 2c 2' 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UUC 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.47 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          50.29 
_exptl_crystal.description                  'long needle-like crystal' 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;100 mM CAPS/Sodium hydroxide [pH 10.5], 1200 mM Sodium phosphate monobasic/800 mM Potassium phosphate dibasic, and 200 mM Lithium sulfate
;
_exptl_crystal_grow.pdbx_pH_range   10.5 
_exptl_crystal_grow.temp            294 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-09-24 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    'Cryogenically-cooled single crystal Si(220) side bounce monochromator' 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97918 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 24-ID-E' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97918 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   24-ID-E 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          23.29 
_reflns.entry_id                                       8UUC 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.55 
_reflns.d_resolution_low                               40 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     53001 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     0 
_reflns.observed_criterion_sigma_I                     -3 
_reflns.percent_possible_obs                           97.6 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.069 
_reflns.pdbx_Rpim_I_all                                0.026 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.999 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.063 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.55 
_reflns_shell.d_res_low                                     1.58 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.3 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2535 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               7.2 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.643 
_reflns_shell.pdbx_Rpim_I_all                               0.607 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.739 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          96.7 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.525 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               35.41 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UUC 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.55 
_refine.ls_d_res_low                             37.62 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     53001 
_refine.ls_number_reflns_R_free                  5122 
_refine.ls_number_reflns_R_work                  95302 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    96.85 
_refine.ls_percent_reflns_R_free                 5.10 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1773 
_refine.ls_R_factor_R_free                       0.1971 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1762 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.91 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 26.6434 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.1861 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.55 
_refine_hist.d_res_low                        37.62 
_refine_hist.number_atoms_solvent             269 
_refine_hist.number_atoms_total               2906 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2141 
_refine_hist.pdbx_number_atoms_nucleic_acid   438 
_refine_hist.pdbx_number_atoms_ligand         58 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0069  ? 2780 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0353  ? 3847 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0504  ? 416  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0103  ? 430  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 22.7930 ? 549  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.55 1.57  . . 171 3107 96.70 . . . . 0.3554 . . . . . . . . . . . 0.4079 
'X-RAY DIFFRACTION' 1.57 1.59  . . 143 3183 96.07 . . . . 0.3507 . . . . . . . . . . . 0.3805 
'X-RAY DIFFRACTION' 1.59 1.61  . . 178 3161 95.73 . . . . 0.3177 . . . . . . . . . . . 0.3583 
'X-RAY DIFFRACTION' 1.61 1.63  . . 143 3204 96.87 . . . . 0.3182 . . . . . . . . . . . 0.3497 
'X-RAY DIFFRACTION' 1.63 1.65  . . 173 3144 96.54 . . . . 0.3065 . . . . . . . . . . . 0.3021 
'X-RAY DIFFRACTION' 1.65 1.67  . . 165 3136 95.52 . . . . 0.2851 . . . . . . . . . . . 0.3147 
'X-RAY DIFFRACTION' 1.67 1.69  . . 187 3147 96.05 . . . . 0.2796 . . . . . . . . . . . 0.2909 
'X-RAY DIFFRACTION' 1.69 1.72  . . 169 3265 97.95 . . . . 0.2798 . . . . . . . . . . . 0.2833 
'X-RAY DIFFRACTION' 1.72 1.75  . . 139 3081 94.82 . . . . 0.2661 . . . . . . . . . . . 0.3161 
'X-RAY DIFFRACTION' 1.75 1.77  . . 185 3096 93.96 . . . . 0.2604 . . . . . . . . . . . 0.2980 
'X-RAY DIFFRACTION' 1.77 1.80  . . 157 2950 91.65 . . . . 0.2305 . . . . . . . . . . . 0.2683 
'X-RAY DIFFRACTION' 1.80 1.84  . . 187 3184 95.20 . . . . 0.2255 . . . . . . . . . . . 0.2179 
'X-RAY DIFFRACTION' 1.84 1.87  . . 153 3210 98.25 . . . . 0.2082 . . . . . . . . . . . 0.2286 
'X-RAY DIFFRACTION' 1.87 1.91  . . 164 3197 97.62 . . . . 0.1965 . . . . . . . . . . . 0.2446 
'X-RAY DIFFRACTION' 1.91 1.95  . . 205 3135 96.25 . . . . 0.1937 . . . . . . . . . . . 0.2301 
'X-RAY DIFFRACTION' 1.95 2.00  . . 165 3278 99.48 . . . . 0.1945 . . . . . . . . . . . 0.2055 
'X-RAY DIFFRACTION' 2.00 2.05  . . 187 3106 95.34 . . . . 0.1892 . . . . . . . . . . . 0.2286 
'X-RAY DIFFRACTION' 2.05 2.10  . . 177 3282 99.86 . . . . 0.1813 . . . . . . . . . . . 0.2385 
'X-RAY DIFFRACTION' 2.10 2.17  . . 183 3135 96.06 . . . . 0.1825 . . . . . . . . . . . 0.2433 
'X-RAY DIFFRACTION' 2.17 2.24  . . 174 3258 99.85 . . . . 0.1729 . . . . . . . . . . . 0.1758 
'X-RAY DIFFRACTION' 2.24 2.32  . . 167 3207 96.34 . . . . 0.1730 . . . . . . . . . . . 0.2174 
'X-RAY DIFFRACTION' 2.32 2.41  . . 164 3192 97.59 . . . . 0.1742 . . . . . . . . . . . 0.1920 
'X-RAY DIFFRACTION' 2.41 2.52  . . 145 3061 94.13 . . . . 0.1699 . . . . . . . . . . . 0.2165 
'X-RAY DIFFRACTION' 2.52 2.65  . . 183 3206 97.33 . . . . 0.1669 . . . . . . . . . . . 0.1913 
'X-RAY DIFFRACTION' 2.65 2.82  . . 191 3208 98.66 . . . . 0.1808 . . . . . . . . . . . 0.2283 
'X-RAY DIFFRACTION' 2.82 3.03  . . 182 3255 98.96 . . . . 0.1706 . . . . . . . . . . . 0.1793 
'X-RAY DIFFRACTION' 3.03 3.34  . . 173 3244 98.87 . . . . 0.1532 . . . . . . . . . . . 0.1644 
'X-RAY DIFFRACTION' 3.34 3.82  . . 187 3251 98.91 . . . . 0.1459 . . . . . . . . . . . 0.1610 
'X-RAY DIFFRACTION' 3.82 4.81  . . 177 3148 96.32 . . . . 0.1337 . . . . . . . . . . . 0.1443 
'X-RAY DIFFRACTION' 4.81 37.62 . . 148 3271 98.90 . . . . 0.1589 . . . . . . . . . . . 0.1691 
# 
_struct.entry_id                     8UUC 
_struct.title                        
'Crystal structure of a bacterial clusterless MutYX bound to an Abasic site analog (THF) opposite d(8-oxo-G)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UUC 
_struct_keywords.text            
'DNA glycosylase, Base Excision Repair, DNA-protein complex, DNA repair, DNA BINDING PROTEIN, DNA BINDING PROTEIN-DNA complex' 
_struct_keywords.pdbx_keywords   'DNA BINDING PROTEIN/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 5 ? 
G N N 6 ? 
H N N 7 ? 
I N N 8 ? 
J N N 8 ? 
K N N 8 ? 
L N N 8 ? 
M N N 8 ? 
N N N 8 ? 
O N N 8 ? 
P N N 8 ? 
Q N N 8 ? 
R N N 8 ? 
S N N 8 ? 
T N N 5 ? 
U N N 8 ? 
V N N 9 ? 
W N N 9 ? 
X N N 9 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP F7V0V1_EEGSY F7V0V1 ? 1 
;AFVERVRTQGALLYRDLPWRNLDDPYAVLVSEVMLQQTQVVRVGKYWNRFMGMFPTIDALAAASTADVLAQWQGLGYNRR
ALALKRTAEVCSAERGGTLPATNEELQALPGIGPATAAGVMAFAYNRPGVYLETNVRTVFLHELFADREKVSDRELWPLV
EATCPEDDARAWYYALLDYGAHLKAVVANPSRRSAHHTRQSTFEGSRRQKRAELVRLVLAEPGIGIDELAERLDAFERDA
GRKGVDAATFTSIVADLVAEGFFRREGDAFFA
;
20 
2 PDB 8UUC         8UUC   ? 2 ? 1  
3 PDB 8UUC         8UUC   ? 3 ? 1  
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UUC A 4 ? 275 ? F7V0V1 20 ? 291 ? 2 273 
2 2 8UUC B 1 ? 11  ? 8UUC   1  ? 11  ? 1 11  
3 3 8UUC C 1 ? 11  ? 8UUC   1  ? 11  ? 1 11  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UUC GLY A 1 ? UNP F7V0V1 ? ? 'expression tag' -1 1 
1 8UUC HIS A 2 ? UNP F7V0V1 ? ? 'expression tag' 0  2 
1 8UUC MET A 3 ? UNP F7V0V1 ? ? 'expression tag' 1  3 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 7860  ? 
1 MORE         -30   ? 
1 'SSA (A^2)'  14280 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ALA A 4   ? TYR A 17  ? ALA A 2   TYR A 15  1 ? 14 
HELX_P HELX_P2  AA2 ASP A 27  ? GLN A 39  ? ASP A 25  GLN A 37  1 ? 13 
HELX_P HELX_P3  AA3 GLN A 42  ? PHE A 57  ? GLN A 40  PHE A 55  1 ? 16 
HELX_P HELX_P4  AA4 THR A 59  ? ALA A 66  ? THR A 57  ALA A 64  1 ? 8  
HELX_P HELX_P5  AA5 SER A 67  ? GLN A 76  ? SER A 65  GLN A 74  1 ? 10 
HELX_P HELX_P6  AA6 ASN A 81  ? ARG A 98  ? ASN A 79  ARG A 96  1 ? 18 
HELX_P HELX_P7  AA7 THR A 105 ? ALA A 111 ? THR A 103 ALA A 109 1 ? 7  
HELX_P HELX_P8  AA8 GLY A 116 ? ASN A 129 ? GLY A 114 ASN A 127 1 ? 14 
HELX_P HELX_P9  AA9 GLU A 136 ? PHE A 148 ? GLU A 134 PHE A 146 1 ? 13 
HELX_P HELX_P10 AB1 SER A 155 ? CYS A 167 ? SER A 153 CYS A 165 1 ? 13 
HELX_P HELX_P11 AB2 ASP A 171 ? VAL A 190 ? ASP A 169 VAL A 188 1 ? 20 
HELX_P HELX_P12 AB3 ASN A 192 ? SER A 197 ? ASN A 190 SER A 195 5 ? 6  
HELX_P HELX_P13 AB4 SER A 209 ? GLU A 224 ? SER A 207 GLU A 222 1 ? 16 
HELX_P HELX_P14 AB5 ILE A 229 ? ALA A 243 ? ILE A 227 ALA A 241 1 ? 15 
HELX_P HELX_P15 AB6 ASP A 249 ? GLY A 264 ? ASP A 247 GLY A 262 1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1  covale both ? B DC  5   "O3'" ? ? ? 1_555 B 8OG 6  P   ? ? B DC  5   B 8OG 6   1_555 ? ? ? ? ? ? ?            1.599 ? ? 
covale2  covale both ? B 8OG 6   "O3'" ? ? ? 1_555 B DT  7  P   ? ? B 8OG 6   B DT  7   1_555 ? ? ? ? ? ? ?            1.607 ? ? 
covale3  covale both ? C DA  6   "O3'" ? ? ? 1_555 C 3DR 7  P   ? ? C DA  6   C 3DR 7   1_555 ? ? ? ? ? ? ?            1.595 ? ? 
covale4  covale both ? C 3DR 7   "O3'" ? ? ? 1_555 C DG  8  P   ? ? C 3DR 7   C DG  8   1_555 ? ? ? ? ? ? ?            1.593 ? ? 
metalc1  metalc ?    ? A ASP 70  OD2   ? ? ? 1_555 E NA  .  NA  ? ? A ASP 68  A NA  302 1_555 ? ? ? ? ? ? ?            2.477 ? ? 
metalc2  metalc ?    ? A GLN 110 O     ? ? ? 1_555 F MG  .  MG  ? ? A GLN 108 A MG  303 1_555 ? ? ? ? ? ? ?            2.472 ? ? 
metalc3  metalc ?    ? A LEU 112 O     ? ? ? 1_555 F MG  .  MG  ? ? A LEU 110 A MG  303 1_555 ? ? ? ? ? ? ?            2.725 ? ? 
metalc4  metalc ?    ? A ILE 115 O     ? ? ? 1_555 F MG  .  MG  ? ? A ILE 113 A MG  303 1_555 ? ? ? ? ? ? ?            2.667 ? ? 
metalc5  metalc ?    ? A LYS 187 O     ? ? ? 1_555 D NA  .  NA  ? ? A LYS 185 A NA  301 1_555 ? ? ? ? ? ? ?            2.688 ? ? 
metalc6  metalc ?    ? A VAL 190 O     ? ? ? 1_555 D NA  .  NA  ? ? A VAL 188 A NA  301 1_555 ? ? ? ? ? ? ?            2.685 ? ? 
metalc7  metalc ?    ? D NA  .   NA    ? ? ? 1_555 V HOH .  O   ? ? A NA  301 A HOH 519 1_555 ? ? ? ? ? ? ?            2.888 ? ? 
metalc8  metalc ?    ? E NA  .   NA    ? ? ? 1_555 V HOH .  O   ? ? A NA  302 A HOH 571 1_555 ? ? ? ? ? ? ?            2.491 ? ? 
metalc9  metalc ?    ? E NA  .   NA    ? ? ? 1_555 V HOH .  O   ? ? A NA  302 A HOH 590 1_555 ? ? ? ? ? ? ?            2.585 ? ? 
metalc10 metalc ?    ? F MG  .   MG    ? ? ? 1_555 C DC  10 OP2 ? ? A MG  303 C DC  10  1_555 ? ? ? ? ? ? ?            2.790 ? ? 
metalc11 metalc ?    ? V HOH .   O     ? ? ? 1_555 T MG  .  MG  ? ? A HOH 548 B MG  101 1_555 ? ? ? ? ? ? ?            2.506 ? ? 
metalc12 metalc ?    ? V HOH .   O     ? ? ? 1_555 T MG  .  MG  ? ? A HOH 567 B MG  101 1_555 ? ? ? ? ? ? ?            2.393 ? ? 
metalc13 metalc ?    ? T MG  .   MG    ? ? ? 1_555 W HOH .  O   ? ? B MG  101 B HOH 224 1_555 ? ? ? ? ? ? ?            2.541 ? ? 
metalc14 metalc ?    ? T MG  .   MG    ? ? ? 1_555 X HOH .  O   ? ? B MG  101 C HOH 229 1_555 ? ? ? ? ? ? ?            2.534 ? ? 
metalc15 metalc ?    ? T MG  .   MG    ? ? ? 1_555 X HOH .  O   ? ? B MG  101 C HOH 233 1_555 ? ? ? ? ? ? ?            2.793 ? ? 
hydrog1  hydrog ?    ? B DA  2   N1    ? ? ? 1_555 C DT  11 N3  ? ? B DA  2   C DT  11  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog2  hydrog ?    ? B DA  2   N6    ? ? ? 1_555 C DT  11 O4  ? ? B DA  2   C DT  11  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog3  hydrog ?    ? B DG  3   N1    ? ? ? 1_555 C DC  10 N3  ? ? B DG  3   C DC  10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog4  hydrog ?    ? B DG  3   N2    ? ? ? 1_555 C DC  10 O2  ? ? B DG  3   C DC  10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog5  hydrog ?    ? B DG  3   O6    ? ? ? 1_555 C DC  10 N4  ? ? B DG  3   C DC  10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog6  hydrog ?    ? B DA  4   N1    ? ? ? 1_555 C DT  9  N3  ? ? B DA  4   C DT  9   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog7  hydrog ?    ? B DA  4   N6    ? ? ? 1_555 C DT  9  O4  ? ? B DA  4   C DT  9   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog8  hydrog ?    ? B DC  5   N3    ? ? ? 1_555 C DG  8  N1  ? ? B DC  5   C DG  8   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog9  hydrog ?    ? B DC  5   N4    ? ? ? 1_555 C DG  8  O6  ? ? B DC  5   C DG  8   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog10 hydrog ?    ? B DC  5   O2    ? ? ? 1_555 C DG  8  N2  ? ? B DC  5   C DG  8   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog11 hydrog ?    ? B DT  7   N3    ? ? ? 1_555 C DA  6  N1  ? ? B DT  7   C DA  6   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog12 hydrog ?    ? B DT  7   O4    ? ? ? 1_555 C DA  6  N6  ? ? B DT  7   C DA  6   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog13 hydrog ?    ? B DG  8   N1    ? ? ? 1_555 C DC  5  N3  ? ? B DG  8   C DC  5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog14 hydrog ?    ? B DG  8   N2    ? ? ? 1_555 C DC  5  O2  ? ? B DG  8   C DC  5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog15 hydrog ?    ? B DG  8   O6    ? ? ? 1_555 C DC  5  N4  ? ? B DG  8   C DC  5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog16 hydrog ?    ? B DG  9   N1    ? ? ? 1_555 C DC  4  N3  ? ? B DG  9   C DC  4   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog17 hydrog ?    ? B DG  9   N2    ? ? ? 1_555 C DC  4  O2  ? ? B DG  9   C DC  4   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog18 hydrog ?    ? B DG  9   O6    ? ? ? 1_555 C DC  4  N4  ? ? B DG  9   C DC  4   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog19 hydrog ?    ? B DA  10  N1    ? ? ? 1_555 C DT  3  N3  ? ? B DA  10  C DT  3   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog20 hydrog ?    ? B DA  10  N6    ? ? ? 1_555 C DT  3  O4  ? ? B DA  10  C DT  3   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog21 hydrog ?    ? B DC  11  N3    ? ? ? 1_555 C DG  2  N1  ? ? B DC  11  C DG  2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog22 hydrog ?    ? B DC  11  N4    ? ? ? 1_555 C DG  2  O6  ? ? B DC  11  C DG  2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog23 hydrog ?    ? B DC  11  O2    ? ? ? 1_555 C DG  2  N2  ? ? B DC  11  C DG  2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
covale ? ? 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD2 ? A ASP 70  ? A ASP 68  ? 1_555 NA ? E NA . ? A NA 302 ? 1_555 O   ? V HOH .   ? A HOH 571 ? 1_555 110.7 ? 
2  OD2 ? A ASP 70  ? A ASP 68  ? 1_555 NA ? E NA . ? A NA 302 ? 1_555 O   ? V HOH .   ? A HOH 590 ? 1_555 110.7 ? 
3  O   ? V HOH .   ? A HOH 571 ? 1_555 NA ? E NA . ? A NA 302 ? 1_555 O   ? V HOH .   ? A HOH 590 ? 1_555 114.3 ? 
4  O   ? A GLN 110 ? A GLN 108 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 O   ? A LEU 112 ? A LEU 110 ? 1_555 96.3  ? 
5  O   ? A GLN 110 ? A GLN 108 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 O   ? A ILE 115 ? A ILE 113 ? 1_555 79.5  ? 
6  O   ? A LEU 112 ? A LEU 110 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 O   ? A ILE 115 ? A ILE 113 ? 1_555 84.4  ? 
7  O   ? A GLN 110 ? A GLN 108 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 OP2 ? C DC  10  ? C DC  10  ? 1_555 132.7 ? 
8  O   ? A LEU 112 ? A LEU 110 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 OP2 ? C DC  10  ? C DC  10  ? 1_555 123.6 ? 
9  O   ? A ILE 115 ? A ILE 113 ? 1_555 MG ? F MG . ? A MG 303 ? 1_555 OP2 ? C DC  10  ? C DC  10  ? 1_555 80.2  ? 
10 O   ? A LYS 187 ? A LYS 185 ? 1_555 NA ? D NA . ? A NA 301 ? 1_555 O   ? A VAL 190 ? A VAL 188 ? 1_555 87.4  ? 
11 O   ? A LYS 187 ? A LYS 185 ? 1_555 NA ? D NA . ? A NA 301 ? 1_555 O   ? V HOH .   ? A HOH 519 ? 1_555 106.6 ? 
12 O   ? A VAL 190 ? A VAL 188 ? 1_555 NA ? D NA . ? A NA 301 ? 1_555 O   ? V HOH .   ? A HOH 519 ? 1_555 85.9  ? 
13 O   ? V HOH .   ? A HOH 548 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? V HOH .   ? A HOH 567 ? 1_555 69.2  ? 
14 O   ? V HOH .   ? A HOH 548 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? W HOH .   ? B HOH 224 ? 1_555 119.0 ? 
15 O   ? V HOH .   ? A HOH 567 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? W HOH .   ? B HOH 224 ? 1_555 128.0 ? 
16 O   ? V HOH .   ? A HOH 548 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 229 ? 1_555 111.9 ? 
17 O   ? V HOH .   ? A HOH 567 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 229 ? 1_555 143.5 ? 
18 O   ? W HOH .   ? B HOH 224 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 229 ? 1_555 84.8  ? 
19 O   ? V HOH .   ? A HOH 548 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 233 ? 1_555 98.0  ? 
20 O   ? V HOH .   ? A HOH 567 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 233 ? 1_555 62.9  ? 
21 O   ? W HOH .   ? B HOH 224 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 233 ? 1_555 143.0 ? 
22 O   ? X HOH .   ? C HOH 229 ? 1_555 MG ? T MG . ? B MG 101 ? 1_555 O   ? X HOH .   ? C HOH 233 ? 1_555 81.3  ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   3 
_struct_sheet.details          ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 227 ? GLY A 228 ? ILE A 225 GLY A 226 
AA1 2 ALA A 272 ? PHE A 274 ? ALA A 270 PHE A 272 
AA1 3 ARG A 267 ? GLU A 269 ? ARG A 265 GLU A 267 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 227 ? N ILE A 225 O PHE A 273 ? O PHE A 271 
AA1 2 3 O ALA A 272 ? O ALA A 270 N GLU A 269 ? N GLU A 267 
# 
_pdbx_entry_details.entry_id                   8UUC 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O   A HOH 585 ? ? O A HOH 591 ? ? 1.88 
2 1 O   A HOH 562 ? ? O A HOH 582 ? ? 1.89 
3 1 OP2 B DA  10  ? ? O B HOH 201 ? ? 2.04 
4 1 OP2 C DC  10  ? ? O C HOH 201 ? ? 2.09 
5 1 O   C HOH 224 ? ? O C HOH 234 ? ? 2.09 
6 1 O   A HOH 469 ? ? O A HOH 485 ? ? 2.14 
7 1 O   B HOH 210 ? ? O B HOH 218 ? ? 2.19 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 O A HOH 562 ? ? 1_555 O A HOH 562 ? ? 3_555 1.70 
2 1 O A HOH 401 ? ? 1_555 O A HOH 462 ? ? 8_555 1.83 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 "O4'" B DG 3 ? ? "C1'" B DG 3 ? ? N9 B DG 3 ? ? 110.12 108.30 1.82 0.30 N 
2 1 "O4'" B DC 5 ? ? "C1'" B DC 5 ? ? N1 B DC 5 ? ? 110.55 108.30 2.25 0.30 N 
3 1 "O4'" B DT 7 ? ? "C1'" B DT 7 ? ? N1 B DT 7 ? ? 112.05 108.30 3.75 0.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 134 ? ? -120.62 -166.23 
2 1 ASP A 169 ? ? -142.54 32.85   
3 1 ASN A 190 ? ? -42.42  108.91  
4 1 ASP A 269 ? B 57.12   9.58    
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z               
2 x,-y,-z             
3 -x,y,-z+1/2         
4 -x,-y,z+1/2         
5 x+1/2,y+1/2,z       
6 x+1/2,-y+1/2,-z     
7 -x+1/2,y+1/2,-z+1/2 
8 -x+1/2,-y+1/2,z+1/2 
# 
loop_
_pdbx_refine_tls.pdbx_refine_id 
_pdbx_refine_tls.id 
_pdbx_refine_tls.details 
_pdbx_refine_tls.method 
_pdbx_refine_tls.origin_x 
_pdbx_refine_tls.origin_y 
_pdbx_refine_tls.origin_z 
_pdbx_refine_tls.T[1][1] 
_pdbx_refine_tls.T[2][2] 
_pdbx_refine_tls.T[3][3] 
_pdbx_refine_tls.T[1][2] 
_pdbx_refine_tls.T[1][3] 
_pdbx_refine_tls.T[2][3] 
_pdbx_refine_tls.L[1][1] 
_pdbx_refine_tls.L[2][2] 
_pdbx_refine_tls.L[3][3] 
_pdbx_refine_tls.L[1][2] 
_pdbx_refine_tls.L[1][3] 
_pdbx_refine_tls.L[2][3] 
_pdbx_refine_tls.S[1][1] 
_pdbx_refine_tls.S[2][2] 
_pdbx_refine_tls.S[3][3] 
_pdbx_refine_tls.S[1][2] 
_pdbx_refine_tls.S[1][3] 
_pdbx_refine_tls.S[2][3] 
_pdbx_refine_tls.S[2][1] 
_pdbx_refine_tls.S[3][1] 
_pdbx_refine_tls.S[3][2] 
'X-RAY DIFFRACTION' 1 ? refined 6.282   13.483 18.341 0.174097021136 0.17065429305  0.220033102522 0.0127444850892  
0.0122816588693  -0.00509475934903 1.42825259018 1.08861019717 3.36434851471 -0.354785193246 0.648810375333  -0.612914338006 
7.78191468811e-05 -0.0245929452238 0.0180313918266  0.119698726317   -0.0454118040999 0.0279213637862  -0.0851788115363 
0.193446192249  0.0733642625923  
'X-RAY DIFFRACTION' 2 ? refined 5.876   21.148 47.748 0.263338915251 0.218773514301 0.151053860954 -0.0104202506006 
0.0201433121495  0.0050639492605   4.55089412622 3.40214253431 6.16457865667 -0.567883713436 0.505213388894  0.618236749295  
-0.00738780535651 -0.0399198166827 0.0642133391061  -0.260837490399  0.0858014283639  -0.0370758588271 0.369104831516   
-0.239571099521 0.271667458435   
'X-RAY DIFFRACTION' 3 ? refined -13.082 19.060 27.379 0.292641302088 0.776387891842 0.790703552526 -0.0657463051379 
0.0161075040677  -0.155155688716   8.11439057039 7.01166329613 4.38118239752 -6.09388028103  0.838696107066  -0.725933735677 
-0.380767281465   0.468055622593   -0.0734202046593 -1.1006413521    -1.96155060534   -1.61227610929   -0.214894118639  
-0.107204333963 -0.208677808201  
'X-RAY DIFFRACTION' 4 ? refined 3.520   24.211 31.903 0.240828650655 0.179733386804 0.240315986971 0.0755291234837  
-0.0133856945644 -0.0271657754685  2.95029103179 4.99378296294 5.6639901356  2.23076225902   2.95781137649   -0.623054612454 
-0.10672625223    -0.112966141691  0.177995550314   -0.365664054297  0.285462102975   0.27563133531    -0.186060299083  
-0.270404283102 -0.311508453581  
'X-RAY DIFFRACTION' 5 ? refined 10.888  41.058 27.936 1.0464531825   0.691062793839 1.21736229635  -0.201979799353  0.205571988824 
-0.107126424398   2.00011853539 4.71205210463 6.26677981471 -6.91463492837  -3.38021226028  2.60297019019   1.6616488759      
0.332033177489   -1.96173000341   -0.79094590738   5.76198358185    -3.21014105872   -0.94760948007   -5.31737936819  
2.51955404447    
'X-RAY DIFFRACTION' 6 ? refined 3.249   25.828 24.343 0.187416104682 0.18261205594  0.167948060241 0.0455585796246  
-0.0109138548221 0.00576983417523  4.46287927704 8.40463333438 2.05215401829 3.9162661232    -0.690721460371 -1.2097476115   
0.020442948889    -0.0271258441307 0.0131547634079  -0.0941223767646 0.163991247718   0.226376325562   -0.0248261105072 
-0.219754794628 -0.0376182265229 
# 
loop_
_pdbx_refine_tls_group.pdbx_refine_id 
_pdbx_refine_tls_group.id 
_pdbx_refine_tls_group.refine_tls_id 
_pdbx_refine_tls_group.beg_auth_asym_id 
_pdbx_refine_tls_group.beg_auth_seq_id 
_pdbx_refine_tls_group.end_auth_asym_id 
_pdbx_refine_tls_group.end_auth_seq_id 
_pdbx_refine_tls_group.selection_details 
_pdbx_refine_tls_group.beg_label_asym_id 
_pdbx_refine_tls_group.beg_label_seq_id 
_pdbx_refine_tls_group.end_label_asym_id 
_pdbx_refine_tls_group.end_label_seq_id 
_pdbx_refine_tls_group.selection 
'X-RAY DIFFRACTION' 1 1 A 1   A 198 '( CHAIN A AND RESID 1:198 )'   ? ? ? ? ? 
'X-RAY DIFFRACTION' 2 2 A 199 A 273 '( CHAIN A AND RESID 199:273 )' ? ? ? ? ? 
'X-RAY DIFFRACTION' 3 3 B 1   B 2   '( CHAIN B AND RESID 1:2 )'     ? ? ? ? ? 
'X-RAY DIFFRACTION' 4 4 B 3   B 9   '( CHAIN B AND RESID 3:9 )'     ? ? ? ? ? 
'X-RAY DIFFRACTION' 5 5 C 1   C 2   '( CHAIN C AND RESID 1:2 )'     ? ? ? ? ? 
'X-RAY DIFFRACTION' 6 6 C 3   C 9   '( CHAIN C AND RESID 3:9 )'     ? ? ? ? ? 
# 
_pdbx_unobs_or_zero_occ_residues.id               1 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num    1 
_pdbx_unobs_or_zero_occ_residues.polymer_flag     Y 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag   1 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id     A 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id     GLY 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id      -1 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code     ? 
_pdbx_unobs_or_zero_occ_residues.label_asym_id    A 
_pdbx_unobs_or_zero_occ_residues.label_comp_id    GLY 
_pdbx_unobs_or_zero_occ_residues.label_seq_id     1 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
3DR "O5'"  O  N N 1   
3DR P      P  N N 2   
3DR OP1    O  N N 3   
3DR OP2    O  N N 4   
3DR OP3    O  N N 5   
3DR "C2'"  C  N N 6   
3DR "C5'"  C  N N 7   
3DR "C4'"  C  N R 8   
3DR "O4'"  O  N N 9   
3DR "C1'"  C  N N 10  
3DR "C3'"  C  N S 11  
3DR "O3'"  O  N N 12  
3DR HOP2   H  N N 13  
3DR HOP3   H  N N 14  
3DR "H2'"  H  N N 15  
3DR "H2''" H  N N 16  
3DR "H5'"  H  N N 17  
3DR "H5''" H  N N 18  
3DR "H4'1" H  N N 19  
3DR "H1'1" H  N N 20  
3DR "H1'2" H  N N 21  
3DR "H3'"  H  N N 22  
3DR "HO3'" H  N N 23  
8OG OP3    O  N N 24  
8OG P      P  N N 25  
8OG OP1    O  N N 26  
8OG OP2    O  N N 27  
8OG "O5'"  O  N N 28  
8OG "C5'"  C  N N 29  
8OG "C4'"  C  N R 30  
8OG "O4'"  O  N N 31  
8OG "C3'"  C  N S 32  
8OG "O3'"  O  N N 33  
8OG "C2'"  C  N N 34  
8OG "C1'"  C  N R 35  
8OG N9     N  N N 36  
8OG C8     C  N N 37  
8OG N7     N  N N 38  
8OG C5     C  N N 39  
8OG C6     C  N N 40  
8OG O6     O  N N 41  
8OG N1     N  N N 42  
8OG C2     C  N N 43  
8OG N2     N  N N 44  
8OG N3     N  N N 45  
8OG C4     C  N N 46  
8OG O8     O  N N 47  
8OG HOP3   H  N N 48  
8OG HOP2   H  N N 49  
8OG "H5'"  H  N N 50  
8OG "H5''" H  N N 51  
8OG "H4'"  H  N N 52  
8OG "H3'"  H  N N 53  
8OG "HO3'" H  N N 54  
8OG "H2'"  H  N N 55  
8OG "H2''" H  N N 56  
8OG "H1'"  H  N N 57  
8OG H7     H  N N 58  
8OG H1     H  N N 59  
8OG H21    H  N N 60  
8OG H22    H  N N 61  
ALA N      N  N N 62  
ALA CA     C  N S 63  
ALA C      C  N N 64  
ALA O      O  N N 65  
ALA CB     C  N N 66  
ALA OXT    O  N N 67  
ALA H      H  N N 68  
ALA H2     H  N N 69  
ALA HA     H  N N 70  
ALA HB1    H  N N 71  
ALA HB2    H  N N 72  
ALA HB3    H  N N 73  
ALA HXT    H  N N 74  
ARG N      N  N N 75  
ARG CA     C  N S 76  
ARG C      C  N N 77  
ARG O      O  N N 78  
ARG CB     C  N N 79  
ARG CG     C  N N 80  
ARG CD     C  N N 81  
ARG NE     N  N N 82  
ARG CZ     C  N N 83  
ARG NH1    N  N N 84  
ARG NH2    N  N N 85  
ARG OXT    O  N N 86  
ARG H      H  N N 87  
ARG H2     H  N N 88  
ARG HA     H  N N 89  
ARG HB2    H  N N 90  
ARG HB3    H  N N 91  
ARG HG2    H  N N 92  
ARG HG3    H  N N 93  
ARG HD2    H  N N 94  
ARG HD3    H  N N 95  
ARG HE     H  N N 96  
ARG HH11   H  N N 97  
ARG HH12   H  N N 98  
ARG HH21   H  N N 99  
ARG HH22   H  N N 100 
ARG HXT    H  N N 101 
ASN N      N  N N 102 
ASN CA     C  N S 103 
ASN C      C  N N 104 
ASN O      O  N N 105 
ASN CB     C  N N 106 
ASN CG     C  N N 107 
ASN OD1    O  N N 108 
ASN ND2    N  N N 109 
ASN OXT    O  N N 110 
ASN H      H  N N 111 
ASN H2     H  N N 112 
ASN HA     H  N N 113 
ASN HB2    H  N N 114 
ASN HB3    H  N N 115 
ASN HD21   H  N N 116 
ASN HD22   H  N N 117 
ASN HXT    H  N N 118 
ASP N      N  N N 119 
ASP CA     C  N S 120 
ASP C      C  N N 121 
ASP O      O  N N 122 
ASP CB     C  N N 123 
ASP CG     C  N N 124 
ASP OD1    O  N N 125 
ASP OD2    O  N N 126 
ASP OXT    O  N N 127 
ASP H      H  N N 128 
ASP H2     H  N N 129 
ASP HA     H  N N 130 
ASP HB2    H  N N 131 
ASP HB3    H  N N 132 
ASP HD2    H  N N 133 
ASP HXT    H  N N 134 
CL  CL     CL N N 135 
CYS N      N  N N 136 
CYS CA     C  N R 137 
CYS C      C  N N 138 
CYS O      O  N N 139 
CYS CB     C  N N 140 
CYS SG     S  N N 141 
CYS OXT    O  N N 142 
CYS H      H  N N 143 
CYS H2     H  N N 144 
CYS HA     H  N N 145 
CYS HB2    H  N N 146 
CYS HB3    H  N N 147 
CYS HG     H  N N 148 
CYS HXT    H  N N 149 
DA  OP3    O  N N 150 
DA  P      P  N N 151 
DA  OP1    O  N N 152 
DA  OP2    O  N N 153 
DA  "O5'"  O  N N 154 
DA  "C5'"  C  N N 155 
DA  "C4'"  C  N R 156 
DA  "O4'"  O  N N 157 
DA  "C3'"  C  N S 158 
DA  "O3'"  O  N N 159 
DA  "C2'"  C  N N 160 
DA  "C1'"  C  N R 161 
DA  N9     N  Y N 162 
DA  C8     C  Y N 163 
DA  N7     N  Y N 164 
DA  C5     C  Y N 165 
DA  C6     C  Y N 166 
DA  N6     N  N N 167 
DA  N1     N  Y N 168 
DA  C2     C  Y N 169 
DA  N3     N  Y N 170 
DA  C4     C  Y N 171 
DA  HOP3   H  N N 172 
DA  HOP2   H  N N 173 
DA  "H5'"  H  N N 174 
DA  "H5''" H  N N 175 
DA  "H4'"  H  N N 176 
DA  "H3'"  H  N N 177 
DA  "HO3'" H  N N 178 
DA  "H2'"  H  N N 179 
DA  "H2''" H  N N 180 
DA  "H1'"  H  N N 181 
DA  H8     H  N N 182 
DA  H61    H  N N 183 
DA  H62    H  N N 184 
DA  H2     H  N N 185 
DC  OP3    O  N N 186 
DC  P      P  N N 187 
DC  OP1    O  N N 188 
DC  OP2    O  N N 189 
DC  "O5'"  O  N N 190 
DC  "C5'"  C  N N 191 
DC  "C4'"  C  N R 192 
DC  "O4'"  O  N N 193 
DC  "C3'"  C  N S 194 
DC  "O3'"  O  N N 195 
DC  "C2'"  C  N N 196 
DC  "C1'"  C  N R 197 
DC  N1     N  N N 198 
DC  C2     C  N N 199 
DC  O2     O  N N 200 
DC  N3     N  N N 201 
DC  C4     C  N N 202 
DC  N4     N  N N 203 
DC  C5     C  N N 204 
DC  C6     C  N N 205 
DC  HOP3   H  N N 206 
DC  HOP2   H  N N 207 
DC  "H5'"  H  N N 208 
DC  "H5''" H  N N 209 
DC  "H4'"  H  N N 210 
DC  "H3'"  H  N N 211 
DC  "HO3'" H  N N 212 
DC  "H2'"  H  N N 213 
DC  "H2''" H  N N 214 
DC  "H1'"  H  N N 215 
DC  H41    H  N N 216 
DC  H42    H  N N 217 
DC  H5     H  N N 218 
DC  H6     H  N N 219 
DG  OP3    O  N N 220 
DG  P      P  N N 221 
DG  OP1    O  N N 222 
DG  OP2    O  N N 223 
DG  "O5'"  O  N N 224 
DG  "C5'"  C  N N 225 
DG  "C4'"  C  N R 226 
DG  "O4'"  O  N N 227 
DG  "C3'"  C  N S 228 
DG  "O3'"  O  N N 229 
DG  "C2'"  C  N N 230 
DG  "C1'"  C  N R 231 
DG  N9     N  Y N 232 
DG  C8     C  Y N 233 
DG  N7     N  Y N 234 
DG  C5     C  Y N 235 
DG  C6     C  N N 236 
DG  O6     O  N N 237 
DG  N1     N  N N 238 
DG  C2     C  N N 239 
DG  N2     N  N N 240 
DG  N3     N  N N 241 
DG  C4     C  Y N 242 
DG  HOP3   H  N N 243 
DG  HOP2   H  N N 244 
DG  "H5'"  H  N N 245 
DG  "H5''" H  N N 246 
DG  "H4'"  H  N N 247 
DG  "H3'"  H  N N 248 
DG  "HO3'" H  N N 249 
DG  "H2'"  H  N N 250 
DG  "H2''" H  N N 251 
DG  "H1'"  H  N N 252 
DG  H8     H  N N 253 
DG  H1     H  N N 254 
DG  H21    H  N N 255 
DG  H22    H  N N 256 
DT  OP3    O  N N 257 
DT  P      P  N N 258 
DT  OP1    O  N N 259 
DT  OP2    O  N N 260 
DT  "O5'"  O  N N 261 
DT  "C5'"  C  N N 262 
DT  "C4'"  C  N R 263 
DT  "O4'"  O  N N 264 
DT  "C3'"  C  N S 265 
DT  "O3'"  O  N N 266 
DT  "C2'"  C  N N 267 
DT  "C1'"  C  N R 268 
DT  N1     N  N N 269 
DT  C2     C  N N 270 
DT  O2     O  N N 271 
DT  N3     N  N N 272 
DT  C4     C  N N 273 
DT  O4     O  N N 274 
DT  C5     C  N N 275 
DT  C7     C  N N 276 
DT  C6     C  N N 277 
DT  HOP3   H  N N 278 
DT  HOP2   H  N N 279 
DT  "H5'"  H  N N 280 
DT  "H5''" H  N N 281 
DT  "H4'"  H  N N 282 
DT  "H3'"  H  N N 283 
DT  "HO3'" H  N N 284 
DT  "H2'"  H  N N 285 
DT  "H2''" H  N N 286 
DT  "H1'"  H  N N 287 
DT  H3     H  N N 288 
DT  H71    H  N N 289 
DT  H72    H  N N 290 
DT  H73    H  N N 291 
DT  H6     H  N N 292 
EDO C1     C  N N 293 
EDO O1     O  N N 294 
EDO C2     C  N N 295 
EDO O2     O  N N 296 
EDO H11    H  N N 297 
EDO H12    H  N N 298 
EDO HO1    H  N N 299 
EDO H21    H  N N 300 
EDO H22    H  N N 301 
EDO HO2    H  N N 302 
GLN N      N  N N 303 
GLN CA     C  N S 304 
GLN C      C  N N 305 
GLN O      O  N N 306 
GLN CB     C  N N 307 
GLN CG     C  N N 308 
GLN CD     C  N N 309 
GLN OE1    O  N N 310 
GLN NE2    N  N N 311 
GLN OXT    O  N N 312 
GLN H      H  N N 313 
GLN H2     H  N N 314 
GLN HA     H  N N 315 
GLN HB2    H  N N 316 
GLN HB3    H  N N 317 
GLN HG2    H  N N 318 
GLN HG3    H  N N 319 
GLN HE21   H  N N 320 
GLN HE22   H  N N 321 
GLN HXT    H  N N 322 
GLU N      N  N N 323 
GLU CA     C  N S 324 
GLU C      C  N N 325 
GLU O      O  N N 326 
GLU CB     C  N N 327 
GLU CG     C  N N 328 
GLU CD     C  N N 329 
GLU OE1    O  N N 330 
GLU OE2    O  N N 331 
GLU OXT    O  N N 332 
GLU H      H  N N 333 
GLU H2     H  N N 334 
GLU HA     H  N N 335 
GLU HB2    H  N N 336 
GLU HB3    H  N N 337 
GLU HG2    H  N N 338 
GLU HG3    H  N N 339 
GLU HE2    H  N N 340 
GLU HXT    H  N N 341 
GLY N      N  N N 342 
GLY CA     C  N N 343 
GLY C      C  N N 344 
GLY O      O  N N 345 
GLY OXT    O  N N 346 
GLY H      H  N N 347 
GLY H2     H  N N 348 
GLY HA2    H  N N 349 
GLY HA3    H  N N 350 
GLY HXT    H  N N 351 
HIS N      N  N N 352 
HIS CA     C  N S 353 
HIS C      C  N N 354 
HIS O      O  N N 355 
HIS CB     C  N N 356 
HIS CG     C  Y N 357 
HIS ND1    N  Y N 358 
HIS CD2    C  Y N 359 
HIS CE1    C  Y N 360 
HIS NE2    N  Y N 361 
HIS OXT    O  N N 362 
HIS H      H  N N 363 
HIS H2     H  N N 364 
HIS HA     H  N N 365 
HIS HB2    H  N N 366 
HIS HB3    H  N N 367 
HIS HD1    H  N N 368 
HIS HD2    H  N N 369 
HIS HE1    H  N N 370 
HIS HE2    H  N N 371 
HIS HXT    H  N N 372 
HOH O      O  N N 373 
HOH H1     H  N N 374 
HOH H2     H  N N 375 
ILE N      N  N N 376 
ILE CA     C  N S 377 
ILE C      C  N N 378 
ILE O      O  N N 379 
ILE CB     C  N S 380 
ILE CG1    C  N N 381 
ILE CG2    C  N N 382 
ILE CD1    C  N N 383 
ILE OXT    O  N N 384 
ILE H      H  N N 385 
ILE H2     H  N N 386 
ILE HA     H  N N 387 
ILE HB     H  N N 388 
ILE HG12   H  N N 389 
ILE HG13   H  N N 390 
ILE HG21   H  N N 391 
ILE HG22   H  N N 392 
ILE HG23   H  N N 393 
ILE HD11   H  N N 394 
ILE HD12   H  N N 395 
ILE HD13   H  N N 396 
ILE HXT    H  N N 397 
LEU N      N  N N 398 
LEU CA     C  N S 399 
LEU C      C  N N 400 
LEU O      O  N N 401 
LEU CB     C  N N 402 
LEU CG     C  N N 403 
LEU CD1    C  N N 404 
LEU CD2    C  N N 405 
LEU OXT    O  N N 406 
LEU H      H  N N 407 
LEU H2     H  N N 408 
LEU HA     H  N N 409 
LEU HB2    H  N N 410 
LEU HB3    H  N N 411 
LEU HG     H  N N 412 
LEU HD11   H  N N 413 
LEU HD12   H  N N 414 
LEU HD13   H  N N 415 
LEU HD21   H  N N 416 
LEU HD22   H  N N 417 
LEU HD23   H  N N 418 
LEU HXT    H  N N 419 
LYS N      N  N N 420 
LYS CA     C  N S 421 
LYS C      C  N N 422 
LYS O      O  N N 423 
LYS CB     C  N N 424 
LYS CG     C  N N 425 
LYS CD     C  N N 426 
LYS CE     C  N N 427 
LYS NZ     N  N N 428 
LYS OXT    O  N N 429 
LYS H      H  N N 430 
LYS H2     H  N N 431 
LYS HA     H  N N 432 
LYS HB2    H  N N 433 
LYS HB3    H  N N 434 
LYS HG2    H  N N 435 
LYS HG3    H  N N 436 
LYS HD2    H  N N 437 
LYS HD3    H  N N 438 
LYS HE2    H  N N 439 
LYS HE3    H  N N 440 
LYS HZ1    H  N N 441 
LYS HZ2    H  N N 442 
LYS HZ3    H  N N 443 
LYS HXT    H  N N 444 
MET N      N  N N 445 
MET CA     C  N S 446 
MET C      C  N N 447 
MET O      O  N N 448 
MET CB     C  N N 449 
MET CG     C  N N 450 
MET SD     S  N N 451 
MET CE     C  N N 452 
MET OXT    O  N N 453 
MET H      H  N N 454 
MET H2     H  N N 455 
MET HA     H  N N 456 
MET HB2    H  N N 457 
MET HB3    H  N N 458 
MET HG2    H  N N 459 
MET HG3    H  N N 460 
MET HE1    H  N N 461 
MET HE2    H  N N 462 
MET HE3    H  N N 463 
MET HXT    H  N N 464 
MG  MG     MG N N 465 
NA  NA     NA N N 466 
PHE N      N  N N 467 
PHE CA     C  N S 468 
PHE C      C  N N 469 
PHE O      O  N N 470 
PHE CB     C  N N 471 
PHE CG     C  Y N 472 
PHE CD1    C  Y N 473 
PHE CD2    C  Y N 474 
PHE CE1    C  Y N 475 
PHE CE2    C  Y N 476 
PHE CZ     C  Y N 477 
PHE OXT    O  N N 478 
PHE H      H  N N 479 
PHE H2     H  N N 480 
PHE HA     H  N N 481 
PHE HB2    H  N N 482 
PHE HB3    H  N N 483 
PHE HD1    H  N N 484 
PHE HD2    H  N N 485 
PHE HE1    H  N N 486 
PHE HE2    H  N N 487 
PHE HZ     H  N N 488 
PHE HXT    H  N N 489 
PO4 P      P  N N 490 
PO4 O1     O  N N 491 
PO4 O2     O  N N 492 
PO4 O3     O  N N 493 
PO4 O4     O  N N 494 
PRO N      N  N N 495 
PRO CA     C  N S 496 
PRO C      C  N N 497 
PRO O      O  N N 498 
PRO CB     C  N N 499 
PRO CG     C  N N 500 
PRO CD     C  N N 501 
PRO OXT    O  N N 502 
PRO H      H  N N 503 
PRO HA     H  N N 504 
PRO HB2    H  N N 505 
PRO HB3    H  N N 506 
PRO HG2    H  N N 507 
PRO HG3    H  N N 508 
PRO HD2    H  N N 509 
PRO HD3    H  N N 510 
PRO HXT    H  N N 511 
SER N      N  N N 512 
SER CA     C  N S 513 
SER C      C  N N 514 
SER O      O  N N 515 
SER CB     C  N N 516 
SER OG     O  N N 517 
SER OXT    O  N N 518 
SER H      H  N N 519 
SER H2     H  N N 520 
SER HA     H  N N 521 
SER HB2    H  N N 522 
SER HB3    H  N N 523 
SER HG     H  N N 524 
SER HXT    H  N N 525 
THR N      N  N N 526 
THR CA     C  N S 527 
THR C      C  N N 528 
THR O      O  N N 529 
THR CB     C  N R 530 
THR OG1    O  N N 531 
THR CG2    C  N N 532 
THR OXT    O  N N 533 
THR H      H  N N 534 
THR H2     H  N N 535 
THR HA     H  N N 536 
THR HB     H  N N 537 
THR HG1    H  N N 538 
THR HG21   H  N N 539 
THR HG22   H  N N 540 
THR HG23   H  N N 541 
THR HXT    H  N N 542 
TRP N      N  N N 543 
TRP CA     C  N S 544 
TRP C      C  N N 545 
TRP O      O  N N 546 
TRP CB     C  N N 547 
TRP CG     C  Y N 548 
TRP CD1    C  Y N 549 
TRP CD2    C  Y N 550 
TRP NE1    N  Y N 551 
TRP CE2    C  Y N 552 
TRP CE3    C  Y N 553 
TRP CZ2    C  Y N 554 
TRP CZ3    C  Y N 555 
TRP CH2    C  Y N 556 
TRP OXT    O  N N 557 
TRP H      H  N N 558 
TRP H2     H  N N 559 
TRP HA     H  N N 560 
TRP HB2    H  N N 561 
TRP HB3    H  N N 562 
TRP HD1    H  N N 563 
TRP HE1    H  N N 564 
TRP HE3    H  N N 565 
TRP HZ2    H  N N 566 
TRP HZ3    H  N N 567 
TRP HH2    H  N N 568 
TRP HXT    H  N N 569 
TYR N      N  N N 570 
TYR CA     C  N S 571 
TYR C      C  N N 572 
TYR O      O  N N 573 
TYR CB     C  N N 574 
TYR CG     C  Y N 575 
TYR CD1    C  Y N 576 
TYR CD2    C  Y N 577 
TYR CE1    C  Y N 578 
TYR CE2    C  Y N 579 
TYR CZ     C  Y N 580 
TYR OH     O  N N 581 
TYR OXT    O  N N 582 
TYR H      H  N N 583 
TYR H2     H  N N 584 
TYR HA     H  N N 585 
TYR HB2    H  N N 586 
TYR HB3    H  N N 587 
TYR HD1    H  N N 588 
TYR HD2    H  N N 589 
TYR HE1    H  N N 590 
TYR HE2    H  N N 591 
TYR HH     H  N N 592 
TYR HXT    H  N N 593 
VAL N      N  N N 594 
VAL CA     C  N S 595 
VAL C      C  N N 596 
VAL O      O  N N 597 
VAL CB     C  N N 598 
VAL CG1    C  N N 599 
VAL CG2    C  N N 600 
VAL OXT    O  N N 601 
VAL H      H  N N 602 
VAL H2     H  N N 603 
VAL HA     H  N N 604 
VAL HB     H  N N 605 
VAL HG11   H  N N 606 
VAL HG12   H  N N 607 
VAL HG13   H  N N 608 
VAL HG21   H  N N 609 
VAL HG22   H  N N 610 
VAL HG23   H  N N 611 
VAL HXT    H  N N 612 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
3DR "O5'" P      sing N N 1   
3DR "O5'" "C5'"  sing N N 2   
3DR P     OP1    doub N N 3   
3DR P     OP2    sing N N 4   
3DR P     OP3    sing N N 5   
3DR OP2   HOP2   sing N N 6   
3DR OP3   HOP3   sing N N 7   
3DR "C2'" "C1'"  sing N N 8   
3DR "C2'" "C3'"  sing N N 9   
3DR "C2'" "H2'"  sing N N 10  
3DR "C2'" "H2''" sing N N 11  
3DR "C5'" "C4'"  sing N N 12  
3DR "C5'" "H5'"  sing N N 13  
3DR "C5'" "H5''" sing N N 14  
3DR "C4'" "O4'"  sing N N 15  
3DR "C4'" "C3'"  sing N N 16  
3DR "C4'" "H4'1" sing N N 17  
3DR "O4'" "C1'"  sing N N 18  
3DR "C1'" "H1'1" sing N N 19  
3DR "C1'" "H1'2" sing N N 20  
3DR "C3'" "O3'"  sing N N 21  
3DR "C3'" "H3'"  sing N N 22  
3DR "O3'" "HO3'" sing N N 23  
8OG OP3   P      sing N N 24  
8OG OP3   HOP3   sing N N 25  
8OG P     OP1    doub N N 26  
8OG P     OP2    sing N N 27  
8OG P     "O5'"  sing N N 28  
8OG OP2   HOP2   sing N N 29  
8OG "O5'" "C5'"  sing N N 30  
8OG "C5'" "C4'"  sing N N 31  
8OG "C5'" "H5'"  sing N N 32  
8OG "C5'" "H5''" sing N N 33  
8OG "C4'" "O4'"  sing N N 34  
8OG "C4'" "C3'"  sing N N 35  
8OG "C4'" "H4'"  sing N N 36  
8OG "O4'" "C1'"  sing N N 37  
8OG "C3'" "O3'"  sing N N 38  
8OG "C3'" "C2'"  sing N N 39  
8OG "C3'" "H3'"  sing N N 40  
8OG "O3'" "HO3'" sing N N 41  
8OG "C2'" "C1'"  sing N N 42  
8OG "C2'" "H2'"  sing N N 43  
8OG "C2'" "H2''" sing N N 44  
8OG "C1'" N9     sing N N 45  
8OG "C1'" "H1'"  sing N N 46  
8OG N9    C8     sing N N 47  
8OG N9    C4     sing N N 48  
8OG C8    N7     sing N N 49  
8OG C8    O8     doub N N 50  
8OG N7    C5     sing N N 51  
8OG N7    H7     sing N N 52  
8OG C5    C6     sing N N 53  
8OG C5    C4     doub N N 54  
8OG C6    O6     doub N N 55  
8OG C6    N1     sing N N 56  
8OG N1    C2     sing N N 57  
8OG N1    H1     sing N N 58  
8OG C2    N2     sing N N 59  
8OG C2    N3     doub N N 60  
8OG N2    H21    sing N N 61  
8OG N2    H22    sing N N 62  
8OG N3    C4     sing N N 63  
ALA N     CA     sing N N 64  
ALA N     H      sing N N 65  
ALA N     H2     sing N N 66  
ALA CA    C      sing N N 67  
ALA CA    CB     sing N N 68  
ALA CA    HA     sing N N 69  
ALA C     O      doub N N 70  
ALA C     OXT    sing N N 71  
ALA CB    HB1    sing N N 72  
ALA CB    HB2    sing N N 73  
ALA CB    HB3    sing N N 74  
ALA OXT   HXT    sing N N 75  
ARG N     CA     sing N N 76  
ARG N     H      sing N N 77  
ARG N     H2     sing N N 78  
ARG CA    C      sing N N 79  
ARG CA    CB     sing N N 80  
ARG CA    HA     sing N N 81  
ARG C     O      doub N N 82  
ARG C     OXT    sing N N 83  
ARG CB    CG     sing N N 84  
ARG CB    HB2    sing N N 85  
ARG CB    HB3    sing N N 86  
ARG CG    CD     sing N N 87  
ARG CG    HG2    sing N N 88  
ARG CG    HG3    sing N N 89  
ARG CD    NE     sing N N 90  
ARG CD    HD2    sing N N 91  
ARG CD    HD3    sing N N 92  
ARG NE    CZ     sing N N 93  
ARG NE    HE     sing N N 94  
ARG CZ    NH1    sing N N 95  
ARG CZ    NH2    doub N N 96  
ARG NH1   HH11   sing N N 97  
ARG NH1   HH12   sing N N 98  
ARG NH2   HH21   sing N N 99  
ARG NH2   HH22   sing N N 100 
ARG OXT   HXT    sing N N 101 
ASN N     CA     sing N N 102 
ASN N     H      sing N N 103 
ASN N     H2     sing N N 104 
ASN CA    C      sing N N 105 
ASN CA    CB     sing N N 106 
ASN CA    HA     sing N N 107 
ASN C     O      doub N N 108 
ASN C     OXT    sing N N 109 
ASN CB    CG     sing N N 110 
ASN CB    HB2    sing N N 111 
ASN CB    HB3    sing N N 112 
ASN CG    OD1    doub N N 113 
ASN CG    ND2    sing N N 114 
ASN ND2   HD21   sing N N 115 
ASN ND2   HD22   sing N N 116 
ASN OXT   HXT    sing N N 117 
ASP N     CA     sing N N 118 
ASP N     H      sing N N 119 
ASP N     H2     sing N N 120 
ASP CA    C      sing N N 121 
ASP CA    CB     sing N N 122 
ASP CA    HA     sing N N 123 
ASP C     O      doub N N 124 
ASP C     OXT    sing N N 125 
ASP CB    CG     sing N N 126 
ASP CB    HB2    sing N N 127 
ASP CB    HB3    sing N N 128 
ASP CG    OD1    doub N N 129 
ASP CG    OD2    sing N N 130 
ASP OD2   HD2    sing N N 131 
ASP OXT   HXT    sing N N 132 
CYS N     CA     sing N N 133 
CYS N     H      sing N N 134 
CYS N     H2     sing N N 135 
CYS CA    C      sing N N 136 
CYS CA    CB     sing N N 137 
CYS CA    HA     sing N N 138 
CYS C     O      doub N N 139 
CYS C     OXT    sing N N 140 
CYS CB    SG     sing N N 141 
CYS CB    HB2    sing N N 142 
CYS CB    HB3    sing N N 143 
CYS SG    HG     sing N N 144 
CYS OXT   HXT    sing N N 145 
DA  OP3   P      sing N N 146 
DA  OP3   HOP3   sing N N 147 
DA  P     OP1    doub N N 148 
DA  P     OP2    sing N N 149 
DA  P     "O5'"  sing N N 150 
DA  OP2   HOP2   sing N N 151 
DA  "O5'" "C5'"  sing N N 152 
DA  "C5'" "C4'"  sing N N 153 
DA  "C5'" "H5'"  sing N N 154 
DA  "C5'" "H5''" sing N N 155 
DA  "C4'" "O4'"  sing N N 156 
DA  "C4'" "C3'"  sing N N 157 
DA  "C4'" "H4'"  sing N N 158 
DA  "O4'" "C1'"  sing N N 159 
DA  "C3'" "O3'"  sing N N 160 
DA  "C3'" "C2'"  sing N N 161 
DA  "C3'" "H3'"  sing N N 162 
DA  "O3'" "HO3'" sing N N 163 
DA  "C2'" "C1'"  sing N N 164 
DA  "C2'" "H2'"  sing N N 165 
DA  "C2'" "H2''" sing N N 166 
DA  "C1'" N9     sing N N 167 
DA  "C1'" "H1'"  sing N N 168 
DA  N9    C8     sing Y N 169 
DA  N9    C4     sing Y N 170 
DA  C8    N7     doub Y N 171 
DA  C8    H8     sing N N 172 
DA  N7    C5     sing Y N 173 
DA  C5    C6     sing Y N 174 
DA  C5    C4     doub Y N 175 
DA  C6    N6     sing N N 176 
DA  C6    N1     doub Y N 177 
DA  N6    H61    sing N N 178 
DA  N6    H62    sing N N 179 
DA  N1    C2     sing Y N 180 
DA  C2    N3     doub Y N 181 
DA  C2    H2     sing N N 182 
DA  N3    C4     sing Y N 183 
DC  OP3   P      sing N N 184 
DC  OP3   HOP3   sing N N 185 
DC  P     OP1    doub N N 186 
DC  P     OP2    sing N N 187 
DC  P     "O5'"  sing N N 188 
DC  OP2   HOP2   sing N N 189 
DC  "O5'" "C5'"  sing N N 190 
DC  "C5'" "C4'"  sing N N 191 
DC  "C5'" "H5'"  sing N N 192 
DC  "C5'" "H5''" sing N N 193 
DC  "C4'" "O4'"  sing N N 194 
DC  "C4'" "C3'"  sing N N 195 
DC  "C4'" "H4'"  sing N N 196 
DC  "O4'" "C1'"  sing N N 197 
DC  "C3'" "O3'"  sing N N 198 
DC  "C3'" "C2'"  sing N N 199 
DC  "C3'" "H3'"  sing N N 200 
DC  "O3'" "HO3'" sing N N 201 
DC  "C2'" "C1'"  sing N N 202 
DC  "C2'" "H2'"  sing N N 203 
DC  "C2'" "H2''" sing N N 204 
DC  "C1'" N1     sing N N 205 
DC  "C1'" "H1'"  sing N N 206 
DC  N1    C2     sing N N 207 
DC  N1    C6     sing N N 208 
DC  C2    O2     doub N N 209 
DC  C2    N3     sing N N 210 
DC  N3    C4     doub N N 211 
DC  C4    N4     sing N N 212 
DC  C4    C5     sing N N 213 
DC  N4    H41    sing N N 214 
DC  N4    H42    sing N N 215 
DC  C5    C6     doub N N 216 
DC  C5    H5     sing N N 217 
DC  C6    H6     sing N N 218 
DG  OP3   P      sing N N 219 
DG  OP3   HOP3   sing N N 220 
DG  P     OP1    doub N N 221 
DG  P     OP2    sing N N 222 
DG  P     "O5'"  sing N N 223 
DG  OP2   HOP2   sing N N 224 
DG  "O5'" "C5'"  sing N N 225 
DG  "C5'" "C4'"  sing N N 226 
DG  "C5'" "H5'"  sing N N 227 
DG  "C5'" "H5''" sing N N 228 
DG  "C4'" "O4'"  sing N N 229 
DG  "C4'" "C3'"  sing N N 230 
DG  "C4'" "H4'"  sing N N 231 
DG  "O4'" "C1'"  sing N N 232 
DG  "C3'" "O3'"  sing N N 233 
DG  "C3'" "C2'"  sing N N 234 
DG  "C3'" "H3'"  sing N N 235 
DG  "O3'" "HO3'" sing N N 236 
DG  "C2'" "C1'"  sing N N 237 
DG  "C2'" "H2'"  sing N N 238 
DG  "C2'" "H2''" sing N N 239 
DG  "C1'" N9     sing N N 240 
DG  "C1'" "H1'"  sing N N 241 
DG  N9    C8     sing Y N 242 
DG  N9    C4     sing Y N 243 
DG  C8    N7     doub Y N 244 
DG  C8    H8     sing N N 245 
DG  N7    C5     sing Y N 246 
DG  C5    C6     sing N N 247 
DG  C5    C4     doub Y N 248 
DG  C6    O6     doub N N 249 
DG  C6    N1     sing N N 250 
DG  N1    C2     sing N N 251 
DG  N1    H1     sing N N 252 
DG  C2    N2     sing N N 253 
DG  C2    N3     doub N N 254 
DG  N2    H21    sing N N 255 
DG  N2    H22    sing N N 256 
DG  N3    C4     sing N N 257 
DT  OP3   P      sing N N 258 
DT  OP3   HOP3   sing N N 259 
DT  P     OP1    doub N N 260 
DT  P     OP2    sing N N 261 
DT  P     "O5'"  sing N N 262 
DT  OP2   HOP2   sing N N 263 
DT  "O5'" "C5'"  sing N N 264 
DT  "C5'" "C4'"  sing N N 265 
DT  "C5'" "H5'"  sing N N 266 
DT  "C5'" "H5''" sing N N 267 
DT  "C4'" "O4'"  sing N N 268 
DT  "C4'" "C3'"  sing N N 269 
DT  "C4'" "H4'"  sing N N 270 
DT  "O4'" "C1'"  sing N N 271 
DT  "C3'" "O3'"  sing N N 272 
DT  "C3'" "C2'"  sing N N 273 
DT  "C3'" "H3'"  sing N N 274 
DT  "O3'" "HO3'" sing N N 275 
DT  "C2'" "C1'"  sing N N 276 
DT  "C2'" "H2'"  sing N N 277 
DT  "C2'" "H2''" sing N N 278 
DT  "C1'" N1     sing N N 279 
DT  "C1'" "H1'"  sing N N 280 
DT  N1    C2     sing N N 281 
DT  N1    C6     sing N N 282 
DT  C2    O2     doub N N 283 
DT  C2    N3     sing N N 284 
DT  N3    C4     sing N N 285 
DT  N3    H3     sing N N 286 
DT  C4    O4     doub N N 287 
DT  C4    C5     sing N N 288 
DT  C5    C7     sing N N 289 
DT  C5    C6     doub N N 290 
DT  C7    H71    sing N N 291 
DT  C7    H72    sing N N 292 
DT  C7    H73    sing N N 293 
DT  C6    H6     sing N N 294 
EDO C1    O1     sing N N 295 
EDO C1    C2     sing N N 296 
EDO C1    H11    sing N N 297 
EDO C1    H12    sing N N 298 
EDO O1    HO1    sing N N 299 
EDO C2    O2     sing N N 300 
EDO C2    H21    sing N N 301 
EDO C2    H22    sing N N 302 
EDO O2    HO2    sing N N 303 
GLN N     CA     sing N N 304 
GLN N     H      sing N N 305 
GLN N     H2     sing N N 306 
GLN CA    C      sing N N 307 
GLN CA    CB     sing N N 308 
GLN CA    HA     sing N N 309 
GLN C     O      doub N N 310 
GLN C     OXT    sing N N 311 
GLN CB    CG     sing N N 312 
GLN CB    HB2    sing N N 313 
GLN CB    HB3    sing N N 314 
GLN CG    CD     sing N N 315 
GLN CG    HG2    sing N N 316 
GLN CG    HG3    sing N N 317 
GLN CD    OE1    doub N N 318 
GLN CD    NE2    sing N N 319 
GLN NE2   HE21   sing N N 320 
GLN NE2   HE22   sing N N 321 
GLN OXT   HXT    sing N N 322 
GLU N     CA     sing N N 323 
GLU N     H      sing N N 324 
GLU N     H2     sing N N 325 
GLU CA    C      sing N N 326 
GLU CA    CB     sing N N 327 
GLU CA    HA     sing N N 328 
GLU C     O      doub N N 329 
GLU C     OXT    sing N N 330 
GLU CB    CG     sing N N 331 
GLU CB    HB2    sing N N 332 
GLU CB    HB3    sing N N 333 
GLU CG    CD     sing N N 334 
GLU CG    HG2    sing N N 335 
GLU CG    HG3    sing N N 336 
GLU CD    OE1    doub N N 337 
GLU CD    OE2    sing N N 338 
GLU OE2   HE2    sing N N 339 
GLU OXT   HXT    sing N N 340 
GLY N     CA     sing N N 341 
GLY N     H      sing N N 342 
GLY N     H2     sing N N 343 
GLY CA    C      sing N N 344 
GLY CA    HA2    sing N N 345 
GLY CA    HA3    sing N N 346 
GLY C     O      doub N N 347 
GLY C     OXT    sing N N 348 
GLY OXT   HXT    sing N N 349 
HIS N     CA     sing N N 350 
HIS N     H      sing N N 351 
HIS N     H2     sing N N 352 
HIS CA    C      sing N N 353 
HIS CA    CB     sing N N 354 
HIS CA    HA     sing N N 355 
HIS C     O      doub N N 356 
HIS C     OXT    sing N N 357 
HIS CB    CG     sing N N 358 
HIS CB    HB2    sing N N 359 
HIS CB    HB3    sing N N 360 
HIS CG    ND1    sing Y N 361 
HIS CG    CD2    doub Y N 362 
HIS ND1   CE1    doub Y N 363 
HIS ND1   HD1    sing N N 364 
HIS CD2   NE2    sing Y N 365 
HIS CD2   HD2    sing N N 366 
HIS CE1   NE2    sing Y N 367 
HIS CE1   HE1    sing N N 368 
HIS NE2   HE2    sing N N 369 
HIS OXT   HXT    sing N N 370 
HOH O     H1     sing N N 371 
HOH O     H2     sing N N 372 
ILE N     CA     sing N N 373 
ILE N     H      sing N N 374 
ILE N     H2     sing N N 375 
ILE CA    C      sing N N 376 
ILE CA    CB     sing N N 377 
ILE CA    HA     sing N N 378 
ILE C     O      doub N N 379 
ILE C     OXT    sing N N 380 
ILE CB    CG1    sing N N 381 
ILE CB    CG2    sing N N 382 
ILE CB    HB     sing N N 383 
ILE CG1   CD1    sing N N 384 
ILE CG1   HG12   sing N N 385 
ILE CG1   HG13   sing N N 386 
ILE CG2   HG21   sing N N 387 
ILE CG2   HG22   sing N N 388 
ILE CG2   HG23   sing N N 389 
ILE CD1   HD11   sing N N 390 
ILE CD1   HD12   sing N N 391 
ILE CD1   HD13   sing N N 392 
ILE OXT   HXT    sing N N 393 
LEU N     CA     sing N N 394 
LEU N     H      sing N N 395 
LEU N     H2     sing N N 396 
LEU CA    C      sing N N 397 
LEU CA    CB     sing N N 398 
LEU CA    HA     sing N N 399 
LEU C     O      doub N N 400 
LEU C     OXT    sing N N 401 
LEU CB    CG     sing N N 402 
LEU CB    HB2    sing N N 403 
LEU CB    HB3    sing N N 404 
LEU CG    CD1    sing N N 405 
LEU CG    CD2    sing N N 406 
LEU CG    HG     sing N N 407 
LEU CD1   HD11   sing N N 408 
LEU CD1   HD12   sing N N 409 
LEU CD1   HD13   sing N N 410 
LEU CD2   HD21   sing N N 411 
LEU CD2   HD22   sing N N 412 
LEU CD2   HD23   sing N N 413 
LEU OXT   HXT    sing N N 414 
LYS N     CA     sing N N 415 
LYS N     H      sing N N 416 
LYS N     H2     sing N N 417 
LYS CA    C      sing N N 418 
LYS CA    CB     sing N N 419 
LYS CA    HA     sing N N 420 
LYS C     O      doub N N 421 
LYS C     OXT    sing N N 422 
LYS CB    CG     sing N N 423 
LYS CB    HB2    sing N N 424 
LYS CB    HB3    sing N N 425 
LYS CG    CD     sing N N 426 
LYS CG    HG2    sing N N 427 
LYS CG    HG3    sing N N 428 
LYS CD    CE     sing N N 429 
LYS CD    HD2    sing N N 430 
LYS CD    HD3    sing N N 431 
LYS CE    NZ     sing N N 432 
LYS CE    HE2    sing N N 433 
LYS CE    HE3    sing N N 434 
LYS NZ    HZ1    sing N N 435 
LYS NZ    HZ2    sing N N 436 
LYS NZ    HZ3    sing N N 437 
LYS OXT   HXT    sing N N 438 
MET N     CA     sing N N 439 
MET N     H      sing N N 440 
MET N     H2     sing N N 441 
MET CA    C      sing N N 442 
MET CA    CB     sing N N 443 
MET CA    HA     sing N N 444 
MET C     O      doub N N 445 
MET C     OXT    sing N N 446 
MET CB    CG     sing N N 447 
MET CB    HB2    sing N N 448 
MET CB    HB3    sing N N 449 
MET CG    SD     sing N N 450 
MET CG    HG2    sing N N 451 
MET CG    HG3    sing N N 452 
MET SD    CE     sing N N 453 
MET CE    HE1    sing N N 454 
MET CE    HE2    sing N N 455 
MET CE    HE3    sing N N 456 
MET OXT   HXT    sing N N 457 
PHE N     CA     sing N N 458 
PHE N     H      sing N N 459 
PHE N     H2     sing N N 460 
PHE CA    C      sing N N 461 
PHE CA    CB     sing N N 462 
PHE CA    HA     sing N N 463 
PHE C     O      doub N N 464 
PHE C     OXT    sing N N 465 
PHE CB    CG     sing N N 466 
PHE CB    HB2    sing N N 467 
PHE CB    HB3    sing N N 468 
PHE CG    CD1    doub Y N 469 
PHE CG    CD2    sing Y N 470 
PHE CD1   CE1    sing Y N 471 
PHE CD1   HD1    sing N N 472 
PHE CD2   CE2    doub Y N 473 
PHE CD2   HD2    sing N N 474 
PHE CE1   CZ     doub Y N 475 
PHE CE1   HE1    sing N N 476 
PHE CE2   CZ     sing Y N 477 
PHE CE2   HE2    sing N N 478 
PHE CZ    HZ     sing N N 479 
PHE OXT   HXT    sing N N 480 
PO4 P     O1     doub N N 481 
PO4 P     O2     sing N N 482 
PO4 P     O3     sing N N 483 
PO4 P     O4     sing N N 484 
PRO N     CA     sing N N 485 
PRO N     CD     sing N N 486 
PRO N     H      sing N N 487 
PRO CA    C      sing N N 488 
PRO CA    CB     sing N N 489 
PRO CA    HA     sing N N 490 
PRO C     O      doub N N 491 
PRO C     OXT    sing N N 492 
PRO CB    CG     sing N N 493 
PRO CB    HB2    sing N N 494 
PRO CB    HB3    sing N N 495 
PRO CG    CD     sing N N 496 
PRO CG    HG2    sing N N 497 
PRO CG    HG3    sing N N 498 
PRO CD    HD2    sing N N 499 
PRO CD    HD3    sing N N 500 
PRO OXT   HXT    sing N N 501 
SER N     CA     sing N N 502 
SER N     H      sing N N 503 
SER N     H2     sing N N 504 
SER CA    C      sing N N 505 
SER CA    CB     sing N N 506 
SER CA    HA     sing N N 507 
SER C     O      doub N N 508 
SER C     OXT    sing N N 509 
SER CB    OG     sing N N 510 
SER CB    HB2    sing N N 511 
SER CB    HB3    sing N N 512 
SER OG    HG     sing N N 513 
SER OXT   HXT    sing N N 514 
THR N     CA     sing N N 515 
THR N     H      sing N N 516 
THR N     H2     sing N N 517 
THR CA    C      sing N N 518 
THR CA    CB     sing N N 519 
THR CA    HA     sing N N 520 
THR C     O      doub N N 521 
THR C     OXT    sing N N 522 
THR CB    OG1    sing N N 523 
THR CB    CG2    sing N N 524 
THR CB    HB     sing N N 525 
THR OG1   HG1    sing N N 526 
THR CG2   HG21   sing N N 527 
THR CG2   HG22   sing N N 528 
THR CG2   HG23   sing N N 529 
THR OXT   HXT    sing N N 530 
TRP N     CA     sing N N 531 
TRP N     H      sing N N 532 
TRP N     H2     sing N N 533 
TRP CA    C      sing N N 534 
TRP CA    CB     sing N N 535 
TRP CA    HA     sing N N 536 
TRP C     O      doub N N 537 
TRP C     OXT    sing N N 538 
TRP CB    CG     sing N N 539 
TRP CB    HB2    sing N N 540 
TRP CB    HB3    sing N N 541 
TRP CG    CD1    doub Y N 542 
TRP CG    CD2    sing Y N 543 
TRP CD1   NE1    sing Y N 544 
TRP CD1   HD1    sing N N 545 
TRP CD2   CE2    doub Y N 546 
TRP CD2   CE3    sing Y N 547 
TRP NE1   CE2    sing Y N 548 
TRP NE1   HE1    sing N N 549 
TRP CE2   CZ2    sing Y N 550 
TRP CE3   CZ3    doub Y N 551 
TRP CE3   HE3    sing N N 552 
TRP CZ2   CH2    doub Y N 553 
TRP CZ2   HZ2    sing N N 554 
TRP CZ3   CH2    sing Y N 555 
TRP CZ3   HZ3    sing N N 556 
TRP CH2   HH2    sing N N 557 
TRP OXT   HXT    sing N N 558 
TYR N     CA     sing N N 559 
TYR N     H      sing N N 560 
TYR N     H2     sing N N 561 
TYR CA    C      sing N N 562 
TYR CA    CB     sing N N 563 
TYR CA    HA     sing N N 564 
TYR C     O      doub N N 565 
TYR C     OXT    sing N N 566 
TYR CB    CG     sing N N 567 
TYR CB    HB2    sing N N 568 
TYR CB    HB3    sing N N 569 
TYR CG    CD1    doub Y N 570 
TYR CG    CD2    sing Y N 571 
TYR CD1   CE1    sing Y N 572 
TYR CD1   HD1    sing N N 573 
TYR CD2   CE2    doub Y N 574 
TYR CD2   HD2    sing N N 575 
TYR CE1   CZ     doub Y N 576 
TYR CE1   HE1    sing N N 577 
TYR CE2   CZ     sing Y N 578 
TYR CE2   HE2    sing N N 579 
TYR CZ    OH     sing N N 580 
TYR OH    HH     sing N N 581 
TYR OXT   HXT    sing N N 582 
VAL N     CA     sing N N 583 
VAL N     H      sing N N 584 
VAL N     H2     sing N N 585 
VAL CA    C      sing N N 586 
VAL CA    CB     sing N N 587 
VAL CA    HA     sing N N 588 
VAL C     O      doub N N 589 
VAL C     OXT    sing N N 590 
VAL CB    CG1    sing N N 591 
VAL CB    CG2    sing N N 592 
VAL CB    HB     sing N N 593 
VAL CG1   HG11   sing N N 594 
VAL CG1   HG12   sing N N 595 
VAL CG1   HG13   sing N N 596 
VAL CG2   HG21   sing N N 597 
VAL CG2   HG22   sing N N 598 
VAL CG2   HG23   sing N N 599 
VAL OXT   HXT    sing N N 600 
# 
_ndb_struct_conf_na.entry_id   8UUC 
_ndb_struct_conf_na.feature    'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B DA 2  1_555 C DT 11 1_555 -0.013 -0.470 -0.247 -4.009  -14.937 7.633  1 B_DA2:DT11_C B 2  ? C 11 ? 20 1 
1 B DG 3  1_555 C DC 10 1_555 -0.264 -0.205 0.069  0.512   -9.394  3.605  2 B_DG3:DC10_C B 3  ? C 10 ? 19 1 
1 B DA 4  1_555 C DT 9  1_555 0.126  -0.156 0.077  3.678   -7.540  1.481  3 B_DA4:DT9_C  B 4  ? C 9  ? 20 1 
1 B DC 5  1_555 C DG 8  1_555 0.184  -0.115 -0.366 13.079  6.017   -0.344 4 B_DC5:DG8_C  B 5  ? C 8  ? 19 1 
1 B DT 7  1_555 C DA 6  1_555 -0.129 -0.134 -0.073 -13.590 -7.134  4.993  5 B_DT7:DA6_C  B 7  ? C 6  ? 20 1 
1 B DG 8  1_555 C DC 5  1_555 -0.316 -0.184 -0.295 -6.997  -0.863  0.186  6 B_DG8:DC5_C  B 8  ? C 5  ? 19 1 
1 B DG 9  1_555 C DC 4  1_555 -0.177 -0.155 -0.099 -4.081  -13.074 -0.371 7 B_DG9:DC4_C  B 9  ? C 4  ? 19 1 
1 B DA 10 1_555 C DT 3  1_555 0.203  -0.103 0.178  2.068   -7.318  -2.241 8 B_DA10:DT3_C B 10 ? C 3  ? 20 1 
1 B DC 11 1_555 C DG 2  1_555 0.300  -0.217 -0.287 4.563   -1.552  -0.158 9 B_DC11:DG2_C B 11 ? C 2  ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B DA 2  1_555 C DT 11 1_555 B DG 3  1_555 C DC 10 1_555 0.267  0.607  3.114 -5.242 10.440 24.832 -1.258 -1.838 3.004 22.740 
11.418 27.403 1 BB_DA2DG3:DC10DT11_CC B 2  ? C 11 ? B 3  ? C 10 ? 
1 B DG 3  1_555 C DC 10 1_555 B DA 4  1_555 C DT 9  1_555 -0.811 0.252  3.211 -3.184 5.687  37.371 -0.338 0.841  3.269 8.794  
4.923  37.915 2 BB_DG3DA4:DT9DC10_CC  B 3  ? C 10 ? B 4  ? C 9  ? 
1 B DA 4  1_555 C DT 9  1_555 B DC 5  1_555 C DG 8  1_555 0.766  -0.500 3.119 3.110  6.221  27.860 -2.340 -0.880 3.005 12.673 
-6.335 28.699 3 BB_DA4DC5:DG8DT9_CC   B 4  ? C 9  ? B 5  ? C 8  ? 
1 B DT 7  1_555 C DA 6  1_555 B DG 8  1_555 C DC 5  1_555 0.052  1.589  3.222 -0.760 -2.464 43.320 2.382  -0.141 3.130 -3.335 
1.028  43.393 4 BB_DT7DG8:DC5DA6_CC   B 7  ? C 6  ? B 8  ? C 5  ? 
1 B DG 8  1_555 C DC 5  1_555 B DG 9  1_555 C DC 4  1_555 -1.321 0.234  3.214 -5.051 6.015  33.399 -0.565 1.432  3.362 10.289 
8.641  34.284 5 BB_DG8DG9:DC4DC5_CC   B 8  ? C 5  ? B 9  ? C 4  ? 
1 B DG 9  1_555 C DC 4  1_555 B DA 10 1_555 C DT 3  1_555 -0.321 -0.209 3.131 -2.972 1.050  35.878 -0.481 0.114  3.140 1.700  
4.813  36.012 6 BB_DG9DA10:DT3DC4_CC  B 9  ? C 4  ? B 10 ? C 3  ? 
1 B DA 10 1_555 C DT 3  1_555 B DC 11 1_555 C DG 2  1_555 0.690  -0.249 3.145 5.183  2.014  31.931 -0.793 -0.346 3.193 3.626  
-9.333 32.400 7 BB_DA10DC11:DG2DT3_CC B 10 ? C 3  ? B 11 ? C 2  ? 
# 
_pdbx_audit_support.funding_organization   'National Science Foundation (NSF, United States)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           CHE-2204228 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'in silico model' 
_pdbx_initial_refinement_model.source_name      AlphaFold 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 2 2 21' 
_space_group.name_Hall        'C 2c 2' 
_space_group.IT_number        20 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8UUC 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.025752 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011885 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.004430 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C  ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CL ? ? 9.50761 7.44341 ? ? 1.04373  23.83732 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H  ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
MG ? ? 9.41153 2.53737 ? ? 2.59044  63.03566 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N  ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
NA ? ? 9.38062 1.54875 ? ? 3.38349  72.32734 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O  ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P  ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S  ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . HIS A 1 2   ? 1.24607   28.72150 -7.65855 1.000 62.63869  ? 0   HIS A N     1 
ATOM   2    C  CA    . HIS A 1 2   ? 1.14694   28.13397 -6.32395 1.000 53.98620  ? 0   HIS A CA    1 
ATOM   3    C  C     . HIS A 1 2   ? 1.54380   26.65783 -6.38334 1.000 45.71419  ? 0   HIS A C     1 
ATOM   4    O  O     . HIS A 1 2   ? 2.12065   26.20362 -7.37370 1.000 46.35768  ? 0   HIS A O     1 
ATOM   5    C  CB    . HIS A 1 2   ? -0.27333  28.28592 -5.76714 1.000 59.27922  ? 0   HIS A CB    1 
ATOM   6    C  CG    . HIS A 1 2   ? -0.81192  29.68618 -5.82395 1.000 61.86393  ? 0   HIS A CG    1 
ATOM   7    N  ND1   . HIS A 1 2   ? -0.04999  30.76888 -6.21166 1.000 66.61808  ? 0   HIS A ND1   1 
ATOM   8    C  CD2   . HIS A 1 2   ? -2.03775  30.17980 -5.52129 1.000 62.01271  ? 0   HIS A CD2   1 
ATOM   9    C  CE1   . HIS A 1 2   ? -0.78594  31.86559 -6.15706 1.000 65.69769  ? 0   HIS A CE1   1 
ATOM   10   N  NE2   . HIS A 1 2   ? -1.99517  31.53649 -5.73738 1.000 60.40327  ? 0   HIS A NE2   1 
ATOM   11   N  N     . MET A 1 3   ? 1.19873   25.90393 -5.33910 1.000 51.67974  ? 1   MET A N     1 
ATOM   12   C  CA    . MET A 1 3   ? 1.65333   24.52676 -5.18679 1.000 42.06433  ? 1   MET A CA    1 
ATOM   13   C  C     . MET A 1 3   ? 0.57885   23.69906 -4.48661 1.000 39.69839  ? 1   MET A C     1 
ATOM   14   O  O     . MET A 1 3   ? -0.00805  24.15435 -3.50123 1.000 44.31790  ? 1   MET A O     1 
ATOM   15   C  CB    . MET A 1 3   ? 2.94770   24.47876 -4.36477 1.000 46.13705  ? 1   MET A CB    1 
ATOM   16   C  CG    . MET A 1 3   ? 3.66468   23.14347 -4.35882 1.000 49.00490  ? 1   MET A CG    1 
ATOM   17   S  SD    . MET A 1 3   ? 5.43567   23.39385 -4.07046 1.000 50.75373  ? 1   MET A SD    1 
ATOM   18   C  CE    . MET A 1 3   ? 5.37285   25.01150 -3.32888 1.000 41.04330  ? 1   MET A CE    1 
ATOM   19   N  N     . ALA A 1 4   ? 0.34767   22.47734 -4.98090 1.000 41.51146  ? 2   ALA A N     1 
ATOM   20   C  CA    . ALA A 1 4   ? -0.49786  21.51304 -4.27671 1.000 36.27547  ? 2   ALA A CA    1 
ATOM   21   C  C     . ALA A 1 4   ? 0.13429   21.09924 -2.94709 1.000 37.79828  ? 2   ALA A C     1 
ATOM   22   O  O     . ALA A 1 4   ? 1.34552   21.21462 -2.73655 1.000 32.05910  ? 2   ALA A O     1 
ATOM   23   C  CB    . ALA A 1 4   ? -0.74129  20.26461 -5.12761 1.000 32.52203  ? 2   ALA A CB    1 
ATOM   24   N  N     . PHE A 1 5   ? -0.71207  20.56956 -2.05590 1.000 32.94228  ? 3   PHE A N     1 
ATOM   25   C  CA    . PHE A 1 5   ? -0.34344  20.42652 -0.64897 1.000 31.69537  ? 3   PHE A CA    1 
ATOM   26   C  C     . PHE A 1 5   ? 0.85195   19.49471 -0.44409 1.000 28.58011  ? 3   PHE A C     1 
ATOM   27   O  O     . PHE A 1 5   ? 1.82710   19.85600 0.23340  1.000 27.11323  ? 3   PHE A O     1 
ATOM   28   C  CB    . PHE A 1 5   ? -1.54956  19.92126 0.14032  1.000 26.38378  ? 3   PHE A CB    1 
ATOM   29   C  CG    . PHE A 1 5   ? -1.24128  19.65748 1.58114  1.000 25.87805  ? 3   PHE A CG    1 
ATOM   30   C  CD1   . PHE A 1 5   ? -0.94987  20.70925 2.43888  1.000 26.65574  ? 3   PHE A CD1   1 
ATOM   31   C  CD2   . PHE A 1 5   ? -1.23165  18.36623 2.07686  1.000 25.58772  ? 3   PHE A CD2   1 
ATOM   32   C  CE1   . PHE A 1 5   ? -0.65637  20.48234 3.77613  1.000 26.55971  ? 3   PHE A CE1   1 
ATOM   33   C  CE2   . PHE A 1 5   ? -0.94222  18.12623 3.41666  1.000 24.53018  ? 3   PHE A CE2   1 
ATOM   34   C  CZ    . PHE A 1 5   ? -0.66054  19.18355 4.27075  1.000 25.63304  ? 3   PHE A CZ    1 
ATOM   35   N  N     . VAL A 1 6   ? 0.77581   18.26345 -0.96177 1.000 27.21304  ? 4   VAL A N     1 
ATOM   36   C  CA    . VAL A 1 6   ? 1.83358   17.29475 -0.66682 1.000 27.96183  ? 4   VAL A CA    1 
ATOM   37   C  C     . VAL A 1 6   ? 3.17340   17.76504 -1.22685 1.000 33.61144  ? 4   VAL A C     1 
ATOM   38   O  O     . VAL A 1 6   ? 4.23398   17.54088 -0.62022 1.000 31.63514  ? 4   VAL A O     1 
ATOM   39   C  CB    . VAL A 1 6   ? 1.46800   15.89637 -1.19867 1.000 34.83823  ? 4   VAL A CB    1 
ATOM   40   C  CG1   . VAL A 1 6   ? 2.72215   15.00654 -1.21199 1.000 37.88365  ? 4   VAL A CG1   1 
ATOM   41   C  CG2   . VAL A 1 6   ? 0.38029   15.26437 -0.34588 1.000 34.70127  ? 4   VAL A CG2   1 
ATOM   42   N  N     . GLU A 1 7   ? 3.14608   18.42433 -2.38697 1.000 30.99079  ? 5   GLU A N     1 
ATOM   43   C  CA    . GLU A 1 7   ? 4.37314   18.91354 -3.00080 1.000 30.86797  ? 5   GLU A CA    1 
ATOM   44   C  C     . GLU A 1 7   ? 4.95103   20.09035 -2.22783 1.000 34.89719  ? 5   GLU A C     1 
ATOM   45   O  O     . GLU A 1 7   ? 6.17394   20.20653 -2.09289 1.000 32.94829  ? 5   GLU A O     1 
ATOM   46   C  CB    . GLU A 1 7   ? 4.09877   19.31073 -4.44965 1.000 35.89690  ? 5   GLU A CB    1 
ATOM   47   C  CG    . GLU A 1 7   ? 3.83525   18.13087 -5.37103 1.000 48.74593  ? 5   GLU A CG    1 
ATOM   48   C  CD    . GLU A 1 7   ? 5.05850   17.26719 -5.57291 1.000 58.90224  ? 5   GLU A CD    1 
ATOM   49   O  OE1   . GLU A 1 7   ? 6.10122   17.81130 -5.99290 1.000 61.02004  ? 5   GLU A OE1   1 
ATOM   50   O  OE2   . GLU A 1 7   ? 4.99441   16.05206 -5.27854 1.000 63.96996  ? 5   GLU A OE2   1 
ATOM   51   N  N     . ARG A 1 8   ? 4.09426   20.98105 -1.72319 1.000 29.03160  ? 6   ARG A N     1 
ATOM   52   C  CA    . ARG A 1 8   ? 4.58097   22.05154 -0.85079 1.000 31.14613  ? 6   ARG A CA    1 
ATOM   53   C  C     . ARG A 1 8   ? 5.27138   21.47395 0.37922  1.000 31.59948  ? 6   ARG A C     1 
ATOM   54   O  O     . ARG A 1 8   ? 6.35334   21.93001 0.76715  1.000 31.76314  ? 6   ARG A O     1 
ATOM   55   C  CB    . ARG A 1 8   ? 3.42335   22.96946 -0.43635 1.000 33.47831  ? 6   ARG A CB    1 
ATOM   56   C  CG    . ARG A 1 8   ? 3.72447   23.89365 0.72458  1.000 35.54148  ? 6   ARG A CG    1 
ATOM   57   C  CD    . ARG A 1 8   ? 4.65578   25.01737 0.28628  1.000 38.02652  ? 6   ARG A CD    1 
ATOM   58   N  NE    . ARG A 1 8   ? 3.94687   25.99130 -0.53524 1.000 50.06091  ? 6   ARG A NE    1 
ATOM   59   C  CZ    . ARG A 1 8   ? 4.53846   26.95980 -1.22125 1.000 53.92014  ? 6   ARG A CZ    1 
ATOM   60   N  NH1   . ARG A 1 8   ? 5.85971   27.08715 -1.23852 1.000 46.12039  ? 6   ARG A NH1   1 
ATOM   61   N  NH2   . ARG A 1 8   ? 3.78901   27.81348 -1.91361 1.000 53.09030  ? 6   ARG A NH2   1 
ATOM   62   N  N     . VAL A 1 9   ? 4.64588   20.47223 1.01770  1.000 27.75537  ? 7   VAL A N     1 
ATOM   63   C  CA    . VAL A 1 9   ? 5.21268   19.87856 2.22206  1.000 27.52150  ? 7   VAL A CA    1 
ATOM   64   C  C     . VAL A 1 9   ? 6.52518   19.16630 1.91237  1.000 28.12541  ? 7   VAL A C     1 
ATOM   65   O  O     . VAL A 1 9   ? 7.52359   19.34803 2.61694  1.000 27.40758  ? 7   VAL A O     1 
ATOM   66   C  CB    . VAL A 1 9   ? 4.20276   18.92748 2.88448  1.000 25.91380  ? 7   VAL A CB    1 
ATOM   67   C  CG1   . VAL A 1 9   ? 4.86681   18.22908 4.10179  1.000 26.84100  ? 7   VAL A CG1   1 
ATOM   68   C  CG2   . VAL A 1 9   ? 2.96057   19.70634 3.34450  1.000 27.15247  ? 7   VAL A CG2   1 
ATOM   69   N  N     A ARG A 1 10  ? 6.54504   18.33572 0.86891  0.520 30.11282  ? 8   ARG A N     1 
ATOM   70   N  N     B ARG A 1 10  ? 6.54744   18.35411 0.84976  0.480 30.11068  ? 8   ARG A N     1 
ATOM   71   C  CA    A ARG A 1 10  ? 7.76472   17.58647 0.58747  0.520 31.50654  ? 8   ARG A CA    1 
ATOM   72   C  CA    B ARG A 1 10  ? 7.74475   17.56987 0.55292  0.480 31.51168  ? 8   ARG A CA    1 
ATOM   73   C  C     A ARG A 1 10  ? 8.91600   18.51862 0.22885  0.520 31.46929  ? 8   ARG A C     1 
ATOM   74   C  C     B ARG A 1 10  ? 8.91855   18.46043 0.15369  0.480 31.47105  ? 8   ARG A C     1 
ATOM   75   O  O     A ARG A 1 10  ? 10.03158  18.35343 0.73489  0.520 31.73806  ? 8   ARG A O     1 
ATOM   76   O  O     B ARG A 1 10  ? 10.06036  18.19595 0.54647  0.480 31.75446  ? 8   ARG A O     1 
ATOM   77   C  CB    A ARG A 1 10  ? 7.51829   16.56158 -0.51633 0.520 35.33837  ? 8   ARG A CB    1 
ATOM   78   C  CB    B ARG A 1 10  ? 7.44038   16.53596 -0.53352 0.480 35.34900  ? 8   ARG A CB    1 
ATOM   79   C  CG    A ARG A 1 10  ? 6.81154   15.31055 -0.01005 0.520 37.64767  ? 8   ARG A CG    1 
ATOM   80   C  CG    B ARG A 1 10  ? 6.59606   15.35985 -0.02901 0.480 37.77996  ? 8   ARG A CG    1 
ATOM   81   C  CD    A ARG A 1 10  ? 7.72813   14.10390 -0.06650 0.520 41.93453  ? 8   ARG A CD    1 
ATOM   82   C  CD    B ARG A 1 10  ? 6.51871   14.22001 -1.04847 0.480 41.91830  ? 8   ARG A CD    1 
ATOM   83   N  NE    A ARG A 1 10  ? 7.22660   12.98432 0.72240  0.520 43.12791  ? 8   ARG A NE    1 
ATOM   84   N  NE    B ARG A 1 10  ? 6.59448   12.90946 -0.41079 0.480 41.71722  ? 8   ARG A NE    1 
ATOM   85   C  CZ    A ARG A 1 10  ? 7.60456   12.68614 1.95925  0.520 36.55318  ? 8   ARG A CZ    1 
ATOM   86   C  CZ    B ARG A 1 10  ? 5.89575   11.84707 -0.78855 0.480 43.33334  ? 8   ARG A CZ    1 
ATOM   87   N  NH1   A ARG A 1 10  ? 8.45137   13.45247 2.63599  0.520 37.87553  ? 8   ARG A NH1   1 
ATOM   88   N  NH1   B ARG A 1 10  ? 5.04033   11.90508 -1.79498 0.480 47.54864  ? 8   ARG A NH1   1 
ATOM   89   N  NH2   A ARG A 1 10  ? 7.11873   11.59196 2.53363  0.520 35.44105  ? 8   ARG A NH2   1 
ATOM   90   N  NH2   B ARG A 1 10  ? 6.05753   10.69766 -0.13783 0.480 44.46715  ? 8   ARG A NH2   1 
ATOM   91   N  N     . THR A 1 11  ? 8.66763   19.52104 -0.61634 1.000 30.57270  ? 9   THR A N     1 
ATOM   92   C  CA    . THR A 1 11  ? 9.76504   20.40420 -1.01831 1.000 29.75157  ? 9   THR A CA    1 
ATOM   93   C  C     . THR A 1 11  ? 10.21529  21.26745 0.15046  1.000 31.58964  ? 9   THR A C     1 
ATOM   94   O  O     . THR A 1 11  ? 11.41787  21.44192 0.36979  1.000 30.14377  ? 9   THR A O     1 
ATOM   95   C  CB    . THR A 1 11  ? 9.38206   21.28684 -2.21614 1.000 32.58203  ? 9   THR A CB    1 
ATOM   96   O  OG1   . THR A 1 11  ? 8.22286   22.08285 -1.90507 1.000 33.04783  ? 9   THR A OG1   1 
ATOM   97   C  CG2   . THR A 1 11  ? 9.12189   20.43502 -3.46419 1.000 32.87252  ? 9   THR A CG2   1 
ATOM   98   N  N     . GLN A 1 12  ? 9.27061   21.80532 0.92281  1.000 28.95985  ? 10  GLN A N     1 
ATOM   99   C  CA    . GLN A 1 12  ? 9.66488   22.54564 2.11929  1.000 28.37439  ? 10  GLN A CA    1 
ATOM   100  C  C     . GLN A 1 12  ? 10.45106  21.66211 3.07146  1.000 27.59414  ? 10  GLN A C     1 
ATOM   101  O  O     . GLN A 1 12  ? 11.42866  22.11504 3.68171  1.000 30.27579  ? 10  GLN A O     1 
ATOM   102  C  CB    . GLN A 1 12  ? 8.43544   23.12321 2.82398  1.000 28.88199  ? 10  GLN A CB    1 
ATOM   103  C  CG    . GLN A 1 12  ? 7.82275   24.30834 2.05668  1.000 34.63935  ? 10  GLN A CG    1 
ATOM   104  C  CD    . GLN A 1 12  ? 8.72186   25.53342 2.03188  1.000 36.61535  ? 10  GLN A CD    1 
ATOM   105  O  OE1   . GLN A 1 12  ? 9.14310   26.02104 3.08159  1.000 41.14686  ? 10  GLN A OE1   1 
ATOM   106  N  NE2   . GLN A 1 12  ? 9.02072   26.03836 0.83149  1.000 42.65184  ? 10  GLN A NE2   1 
ATOM   107  N  N     . GLY A 1 13  ? 10.03312  20.40077 3.22141  1.000 27.05156  ? 11  GLY A N     1 
ATOM   108  C  CA    . GLY A 1 13  ? 10.72534  19.50935 4.14041  1.000 27.48910  ? 11  GLY A CA    1 
ATOM   109  C  C     . GLY A 1 13  ? 12.16980  19.30458 3.73732  1.000 27.41232  ? 11  GLY A C     1 
ATOM   110  O  O     . GLY A 1 13  ? 13.06255  19.24221 4.59372  1.000 29.04282  ? 11  GLY A O     1 
ATOM   111  N  N     . ALA A 1 14  ? 12.42117  19.21389 2.42453  1.000 27.57714  ? 12  ALA A N     1 
ATOM   112  C  CA    . ALA A 1 14  ? 13.78279  19.07718 1.92217  1.000 31.24187  ? 12  ALA A CA    1 
ATOM   113  C  C     . ALA A 1 14  ? 14.58404  20.35677 2.13241  1.000 34.97636  ? 12  ALA A C     1 
ATOM   114  O  O     . ALA A 1 14  ? 15.77383  20.30115 2.47206  1.000 34.63954  ? 12  ALA A O     1 
ATOM   115  C  CB    . ALA A 1 14  ? 13.75425  18.69423 0.43810  1.000 29.67987  ? 12  ALA A CB    1 
ATOM   116  N  N     . LEU A 1 15  ? 13.95339  21.51727 1.91749  1.000 29.77964  ? 13  LEU A N     1 
ATOM   117  C  CA    . LEU A 1 15  ? 14.61653  22.79816 2.15581  1.000 30.99298  ? 13  LEU A CA    1 
ATOM   118  C  C     . LEU A 1 15  ? 14.96610  23.00970 3.62891  1.000 31.70183  ? 13  LEU A C     1 
ATOM   119  O  O     . LEU A 1 15  ? 16.01163  23.59571 3.94216  1.000 33.85951  ? 13  LEU A O     1 
ATOM   120  C  CB    . LEU A 1 15  ? 13.72733  23.93766 1.66704  1.000 30.59788  ? 13  LEU A CB    1 
ATOM   121  C  CG    . LEU A 1 15  ? 13.54539  24.01172 0.15068  1.000 32.36728  ? 13  LEU A CG    1 
ATOM   122  C  CD1   . LEU A 1 15  ? 12.39117  24.92729 -0.19328 1.000 36.55284  ? 13  LEU A CD1   1 
ATOM   123  C  CD2   . LEU A 1 15  ? 14.84097  24.46661 -0.53991 1.000 31.10472  ? 13  LEU A CD2   1 
ATOM   124  N  N     . LEU A 1 16  ? 14.10022  22.55551 4.53768  1.000 27.86515  ? 14  LEU A N     1 
ATOM   125  C  CA    . LEU A 1 16  ? 14.14822  22.89613 5.95369  1.000 26.81362  ? 14  LEU A CA    1 
ATOM   126  C  C     . LEU A 1 16  ? 14.67099  21.76996 6.83375  1.000 32.05015  ? 14  LEU A C     1 
ATOM   127  O  O     . LEU A 1 16  ? 14.69303  21.93132 8.06032  1.000 31.47794  ? 14  LEU A O     1 
ATOM   128  C  CB    . LEU A 1 16  ? 12.74400  23.30360 6.44386  1.000 28.72617  ? 14  LEU A CB    1 
ATOM   129  C  CG    . LEU A 1 16  ? 12.12733  24.51124 5.74540  1.000 31.89490  ? 14  LEU A CG    1 
ATOM   130  C  CD1   . LEU A 1 16  ? 10.62170  24.60850 6.02630  1.000 29.43360  ? 14  LEU A CD1   1 
ATOM   131  C  CD2   . LEU A 1 16  ? 12.85766  25.78319 6.14498  1.000 32.87269  ? 14  LEU A CD2   1 
ATOM   132  N  N     . TYR A 1 17  ? 15.10820  20.64845 6.25694  1.000 30.52538  ? 15  TYR A N     1 
ATOM   133  C  CA    . TYR A 1 17  ? 15.38208  19.46436 7.07394  1.000 29.08770  ? 15  TYR A CA    1 
ATOM   134  C  C     . TYR A 1 17  ? 16.34900  19.76136 8.21711  1.000 30.04129  ? 15  TYR A C     1 
ATOM   135  O  O     . TYR A 1 17  ? 17.43290  20.32171 8.00746  1.000 29.60646  ? 15  TYR A O     1 
ATOM   136  C  CB    . TYR A 1 17  ? 15.95035  18.34160 6.20497  1.000 32.84650  ? 15  TYR A CB    1 
ATOM   137  C  CG    . TYR A 1 17  ? 16.31802  17.14294 7.03986  1.000 32.87139  ? 15  TYR A CG    1 
ATOM   138  C  CD1   . TYR A 1 17  ? 15.34922  16.23873 7.44131  1.000 31.92680  ? 15  TYR A CD1   1 
ATOM   139  C  CD2   . TYR A 1 17  ? 17.63171  16.93835 7.46429  1.000 30.88137  ? 15  TYR A CD2   1 
ATOM   140  C  CE1   . TYR A 1 17  ? 15.66486  15.14928 8.21207  1.000 33.29114  ? 15  TYR A CE1   1 
ATOM   141  C  CE2   . TYR A 1 17  ? 17.95699  15.85047 8.26635  1.000 34.50627  ? 15  TYR A CE2   1 
ATOM   142  C  CZ    . TYR A 1 17  ? 16.97108  14.95814 8.62362  1.000 36.27654  ? 15  TYR A CZ    1 
ATOM   143  O  OH    . TYR A 1 17  ? 17.26885  13.86748 9.40860  1.000 39.41109  ? 15  TYR A OH    1 
ATOM   144  N  N     . ARG A 1 18  ? 15.97363  19.32209 9.41894  1.000 29.76958  ? 16  ARG A N     1 
ATOM   145  C  CA    . ARG A 1 18  ? 16.78656  19.49291 10.61594 1.000 32.47341  ? 16  ARG A CA    1 
ATOM   146  C  C     . ARG A 1 18  ? 17.38304  18.15221 11.02957 1.000 28.93749  ? 16  ARG A C     1 
ATOM   147  O  O     . ARG A 1 18  ? 16.65337  17.17142 11.20846 1.000 31.97699  ? 16  ARG A O     1 
ATOM   148  C  CB    . ARG A 1 18  ? 15.93537  20.06725 11.74956 1.000 31.45599  ? 16  ARG A CB    1 
ATOM   149  C  CG    . ARG A 1 18  ? 15.57195  21.54362 11.57495 1.000 32.49885  ? 16  ARG A CG    1 
ATOM   150  C  CD    . ARG A 1 18  ? 14.66522  22.01682 12.73178 1.000 30.30363  ? 16  ARG A CD    1 
ATOM   151  N  NE    . ARG A 1 18  ? 13.41463  21.27288 12.76915 1.000 28.94931  ? 16  ARG A NE    1 
ATOM   152  C  CZ    . ARG A 1 18  ? 12.49232  21.42396 13.71237 1.000 29.35635  ? 16  ARG A CZ    1 
ATOM   153  N  NH1   . ARG A 1 18  ? 12.68427  22.24577 14.73625 1.000 33.30447  ? 16  ARG A NH1   1 
ATOM   154  N  NH2   . ARG A 1 18  ? 11.35725  20.73716 13.62884 1.000 30.83550  ? 16  ARG A NH2   1 
ATOM   155  N  N     . ASP A 1 19  ? 18.70284  18.10988 11.19127 1.000 30.82843  ? 17  ASP A N     1 
ATOM   156  C  CA    . ASP A 1 19  ? 19.38152  16.86343 11.55222 1.000 32.70618  ? 17  ASP A CA    1 
ATOM   157  C  C     . ASP A 1 19  ? 19.40408  16.67709 13.07378 1.000 33.92816  ? 17  ASP A C     1 
ATOM   158  O  O     . ASP A 1 19  ? 20.43927  16.74601 13.73538 1.000 39.16502  ? 17  ASP A O     1 
ATOM   159  C  CB    . ASP A 1 19  ? 20.78369  16.85105 10.96411 1.000 35.63811  ? 17  ASP A CB    1 
ATOM   160  C  CG    . ASP A 1 19  ? 21.50499  15.54236 11.20133 1.000 46.27893  ? 17  ASP A CG    1 
ATOM   161  O  OD1   . ASP A 1 19  ? 20.84024  14.48718 11.22223 1.000 53.37236  ? 17  ASP A OD1   1 
ATOM   162  O  OD2   . ASP A 1 19  ? 22.74992  15.56902 11.32356 1.000 52.89315  ? 17  ASP A OD2   1 
ATOM   163  N  N     . LEU A 1 20  ? 18.25174  16.39202 13.60717 1.000 31.34933  ? 18  LEU A N     1 
ATOM   164  C  CA    . LEU A 1 20  ? 18.13704  16.25156 15.05241 1.000 32.95455  ? 18  LEU A CA    1 
ATOM   165  C  C     . LEU A 1 20  ? 18.66909  14.89164 15.51616 1.000 32.97653  ? 18  LEU A C     1 
ATOM   166  O  O     . LEU A 1 20  ? 18.54160  13.89052 14.80490 1.000 31.65320  ? 18  LEU A O     1 
ATOM   167  C  CB    . LEU A 1 20  ? 16.68231  16.43122 15.46889 1.000 30.47999  ? 18  LEU A CB    1 
ATOM   168  C  CG    . LEU A 1 20  ? 16.08844  17.77855 15.02883 1.000 29.97357  ? 18  LEU A CG    1 
ATOM   169  C  CD1   . LEU A 1 20  ? 14.61006  17.86568 15.33326 1.000 30.64762  ? 18  LEU A CD1   1 
ATOM   170  C  CD2   . LEU A 1 20  ? 16.84754  18.93970 15.66102 1.000 38.22669  ? 18  LEU A CD2   1 
ATOM   171  N  N     . PRO A 1 21  ? 19.23973  14.82989 16.72931 1.000 32.65340  ? 19  PRO A N     1 
ATOM   172  C  CA    . PRO A 1 21  ? 19.94212  13.60634 17.16651 1.000 30.86879  ? 19  PRO A CA    1 
ATOM   173  C  C     . PRO A 1 21  ? 19.07678  12.35713 17.23521 1.000 32.25338  ? 19  PRO A C     1 
ATOM   174  O  O     . PRO A 1 21  ? 19.60549  11.24628 17.06804 1.000 29.46822  ? 19  PRO A O     1 
ATOM   175  C  CB    . PRO A 1 21  ? 20.46731  13.98170 18.55948 1.000 37.88496  ? 19  PRO A CB    1 
ATOM   176  C  CG    . PRO A 1 21  ? 20.37898  15.47283 18.63556 1.000 36.27906  ? 19  PRO A CG    1 
ATOM   177  C  CD    . PRO A 1 21  ? 19.26417  15.89126 17.74557 1.000 35.50086  ? 19  PRO A CD    1 
ATOM   178  N  N     . TRP A 1 22  ? 17.77883  12.49754 17.49422 1.000 29.64741  ? 20  TRP A N     1 
ATOM   179  C  CA    . TRP A 1 22  ? 16.87510  11.36251 17.63060 1.000 29.05424  ? 20  TRP A CA    1 
ATOM   180  C  C     . TRP A 1 22  ? 16.22650  10.95091 16.30794 1.000 29.97267  ? 20  TRP A C     1 
ATOM   181  O  O     . TRP A 1 22  ? 15.29670  10.13788 16.31544 1.000 29.12960  ? 20  TRP A O     1 
ATOM   182  C  CB    . TRP A 1 22  ? 15.79174  11.67983 18.66451 1.000 26.56992  ? 20  TRP A CB    1 
ATOM   183  C  CG    . TRP A 1 22  ? 15.20236  13.03941 18.49154 1.000 24.49771  ? 20  TRP A CG    1 
ATOM   184  C  CD1   . TRP A 1 22  ? 14.16709  13.39575 17.65583 1.000 26.86354  ? 20  TRP A CD1   1 
ATOM   185  C  CD2   . TRP A 1 22  ? 15.60191  14.24163 19.16529 1.000 26.98394  ? 20  TRP A CD2   1 
ATOM   186  N  NE1   . TRP A 1 22  ? 13.90538  14.73990 17.77718 1.000 26.97412  ? 20  TRP A NE1   1 
ATOM   187  C  CE2   . TRP A 1 22  ? 14.77863  15.28553 18.68285 1.000 29.50615  ? 20  TRP A CE2   1 
ATOM   188  C  CE3   . TRP A 1 22  ? 16.58013  14.53834 20.12228 1.000 27.59352  ? 20  TRP A CE3   1 
ATOM   189  C  CZ2   . TRP A 1 22  ? 14.90081  16.59996 19.13012 1.000 27.23294  ? 20  TRP A CZ2   1 
ATOM   190  C  CZ3   . TRP A 1 22  ? 16.71175  15.85168 20.56059 1.000 27.13239  ? 20  TRP A CZ3   1 
ATOM   191  C  CH2   . TRP A 1 22  ? 15.87045  16.86200 20.07470 1.000 27.80413  ? 20  TRP A CH2   1 
ATOM   192  N  N     . ARG A 1 23  ? 16.68250  11.48820 15.18525 1.000 28.60167  ? 21  ARG A N     1 
ATOM   193  C  CA    . ARG A 1 23  ? 16.05045  11.18006 13.90539 1.000 29.92122  ? 21  ARG A CA    1 
ATOM   194  C  C     . ARG A 1 23  ? 16.73261  10.00149 13.21809 1.000 31.50023  ? 21  ARG A C     1 
ATOM   195  O  O     . ARG A 1 23  ? 17.93290  9.76159  13.37270 1.000 30.85000  ? 21  ARG A O     1 
ATOM   196  C  CB    . ARG A 1 23  ? 16.05995  12.40766 12.98847 1.000 30.21130  ? 21  ARG A CB    1 
ATOM   197  C  CG    . ARG A 1 23  ? 15.05170  13.47289 13.44696 1.000 30.44856  ? 21  ARG A CG    1 
ATOM   198  C  CD    . ARG A 1 23  ? 14.90121  14.60449 12.43421 1.000 31.80106  ? 21  ARG A CD    1 
ATOM   199  N  NE    . ARG A 1 23  ? 13.72138  15.41390 12.72869 1.000 29.52371  ? 21  ARG A NE    1 
ATOM   200  C  CZ    . ARG A 1 23  ? 13.24327  16.33978 11.90554 1.000 30.01169  ? 21  ARG A CZ    1 
ATOM   201  N  NH1   . ARG A 1 23  ? 13.86865  16.65445 10.77922 1.000 30.46869  ? 21  ARG A NH1   1 
ATOM   202  N  NH2   . ARG A 1 23  ? 12.11011  16.96576 12.22039 1.000 30.95579  ? 21  ARG A NH2   1 
ATOM   203  N  N     . ASN A 1 24  ? 15.93662  9.25366  12.45568 1.000 32.70639  ? 22  ASN A N     1 
ATOM   204  C  CA    . ASN A 1 24  ? 16.43888  8.14223  11.65449 1.000 32.62873  ? 22  ASN A CA    1 
ATOM   205  C  C     . ASN A 1 24  ? 17.09309  7.08745  12.53638 1.000 31.65156  ? 22  ASN A C     1 
ATOM   206  O  O     . ASN A 1 24  ? 18.13296  6.52406  12.19842 1.000 36.17829  ? 22  ASN A O     1 
ATOM   207  C  CB    . ASN A 1 24  ? 17.40006  8.64306  10.57502 1.000 34.27746  ? 22  ASN A CB    1 
ATOM   208  C  CG    . ASN A 1 24  ? 16.76619  9.71254  9.72482  1.000 39.19083  ? 22  ASN A CG    1 
ATOM   209  O  OD1   . ASN A 1 24  ? 15.76341  9.46362  9.06380  1.000 38.51597  ? 22  ASN A OD1   1 
ATOM   210  N  ND2   . ASN A 1 24  ? 17.30708  10.91985 9.77880  1.000 39.53166  ? 22  ASN A ND2   1 
ATOM   211  N  N     . LEU A 1 25  ? 16.47509  6.83142  13.68424 1.000 33.62326  ? 23  LEU A N     1 
ATOM   212  C  CA    . LEU A 1 25  ? 16.86947  5.76366  14.58797 1.000 33.90661  ? 23  LEU A CA    1 
ATOM   213  C  C     . LEU A 1 25  ? 15.97607  4.55321  14.36107 1.000 39.06370  ? 23  LEU A C     1 
ATOM   214  O  O     . LEU A 1 25  ? 14.81461  4.68541  13.97035 1.000 51.16832  ? 23  LEU A O     1 
ATOM   215  C  CB    . LEU A 1 25  ? 16.74177  6.21673  16.04828 1.000 32.11233  ? 23  LEU A CB    1 
ATOM   216  C  CG    . LEU A 1 25  ? 17.63141  7.38774  16.44837 1.000 34.42041  ? 23  LEU A CG    1 
ATOM   217  C  CD1   . LEU A 1 25  ? 17.53793  7.62886  17.94486 1.000 36.47243  ? 23  LEU A CD1   1 
ATOM   218  C  CD2   . LEU A 1 25  ? 19.06373  7.11918  16.00448 1.000 37.71814  ? 23  LEU A CD2   1 
ATOM   219  N  N     . ASP A 1 26  ? 16.51237  3.36929  14.63050 1.000 40.23498  ? 24  ASP A N     1 
ATOM   220  C  CA    . ASP A 1 26  ? 15.66817  2.18761  14.59644 1.000 49.85166  ? 24  ASP A CA    1 
ATOM   221  C  C     . ASP A 1 26  ? 15.14540  1.78317  15.96702 1.000 48.52252  ? 24  ASP A C     1 
ATOM   222  O  O     . ASP A 1 26  ? 14.09644  1.13171  16.03673 1.000 46.95176  ? 24  ASP A O     1 
ATOM   223  C  CB    . ASP A 1 26  ? 16.41873  1.01122  13.96997 1.000 53.24770  ? 24  ASP A CB    1 
ATOM   224  C  CG    . ASP A 1 26  ? 16.20494  0.92476  12.46668 1.000 62.79631  ? 24  ASP A CG    1 
ATOM   225  O  OD1   . ASP A 1 26  ? 15.39283  1.71332  11.92933 1.000 58.94288  ? 24  ASP A OD1   1 
ATOM   226  O  OD2   . ASP A 1 26  ? 16.85229  0.07130  11.82490 1.000 71.52636  ? 24  ASP A OD2   1 
ATOM   227  N  N     . ASP A 1 27  ? 15.81870  2.18100  17.04222 1.000 37.91026  ? 25  ASP A N     1 
ATOM   228  C  CA    . ASP A 1 27  ? 15.45521  1.74185  18.38907 1.000 34.94781  ? 25  ASP A CA    1 
ATOM   229  C  C     . ASP A 1 27  ? 14.17417  2.41191  18.86121 1.000 34.38498  ? 25  ASP A C     1 
ATOM   230  O  O     . ASP A 1 27  ? 14.18356  3.61872  19.13287 1.000 32.86321  ? 25  ASP A O     1 
ATOM   231  C  CB    . ASP A 1 27  ? 16.58658  2.03829  19.36871 1.000 35.36533  ? 25  ASP A CB    1 
ATOM   232  C  CG    . ASP A 1 27  ? 16.23146  1.66206  20.80881 1.000 39.89997  ? 25  ASP A CG    1 
ATOM   233  O  OD1   . ASP A 1 27  ? 15.22962  0.94298  21.02645 1.000 37.90805  ? 25  ASP A OD1   1 
ATOM   234  O  OD2   . ASP A 1 27  ? 16.96198  2.08448  21.72851 1.000 43.48832  ? 25  ASP A OD2   1 
ATOM   235  N  N     . PRO A 1 28  ? 13.06810  1.68182  19.00642 1.000 34.06219  ? 26  PRO A N     1 
ATOM   236  C  CA    . PRO A 1 28  ? 11.81891  2.33402  19.42104 1.000 31.37417  ? 26  PRO A CA    1 
ATOM   237  C  C     . PRO A 1 28  ? 11.90697  2.97838  20.79782 1.000 28.54726  ? 26  PRO A C     1 
ATOM   238  O  O     . PRO A 1 28  ? 11.21995  3.97078  21.06276 1.000 27.82497  ? 26  PRO A O     1 
ATOM   239  C  CB    . PRO A 1 28  ? 10.79984  1.18515  19.39675 1.000 33.00477  ? 26  PRO A CB    1 
ATOM   240  C  CG    . PRO A 1 28  ? 11.42334  0.11786  18.55721 1.000 40.29259  ? 26  PRO A CG    1 
ATOM   241  C  CD    . PRO A 1 28  ? 12.89543  0.24849  18.72313 1.000 38.00067  ? 26  PRO A CD    1 
ATOM   242  N  N     . TYR A 1 29  ? 12.74377  2.44736  21.69151 1.000 28.83130  ? 27  TYR A N     1 
ATOM   243  C  CA    . TYR A 1 29  ? 12.85053  3.05320  23.01480 1.000 27.53309  ? 27  TYR A CA    1 
ATOM   244  C  C     . TYR A 1 29  ? 13.49621  4.43346  22.93999 1.000 26.30786  ? 27  TYR A C     1 
ATOM   245  O  O     . TYR A 1 29  ? 13.00867  5.38283  23.55176 1.000 24.61399  ? 27  TYR A O     1 
ATOM   246  C  CB    . TYR A 1 29  ? 13.63100  2.13605  23.95438 1.000 25.59008  ? 27  TYR A CB    1 
ATOM   247  C  CG    . TYR A 1 29  ? 14.06657  2.82012  25.23882 1.000 27.45361  ? 27  TYR A CG    1 
ATOM   248  C  CD1   . TYR A 1 29  ? 13.13328  3.19105  26.21050 1.000 25.59410  ? 27  TYR A CD1   1 
ATOM   249  C  CD2   . TYR A 1 29  ? 15.41645  3.09737  25.47713 1.000 28.06261  ? 27  TYR A CD2   1 
ATOM   250  C  CE1   . TYR A 1 29  ? 13.52247  3.82876  27.35925 1.000 26.24176  ? 27  TYR A CE1   1 
ATOM   251  C  CE2   . TYR A 1 29  ? 15.81290  3.73121  26.62919 1.000 28.73732  ? 27  TYR A CE2   1 
ATOM   252  C  CZ    . TYR A 1 29  ? 14.86286  4.08042  27.57418 1.000 26.95782  ? 27  TYR A CZ    1 
ATOM   253  O  OH    . TYR A 1 29  ? 15.25899  4.71308  28.72977 1.000 28.92046  ? 27  TYR A OH    1 
ATOM   254  N  N     . ALA A 1 30  ? 14.61352  4.56084  22.20918 1.000 26.80595  ? 28  ALA A N     1 
ATOM   255  C  CA    . ALA A 1 30  ? 15.25679  5.86408  22.05036 1.000 26.38333  ? 28  ALA A CA    1 
ATOM   256  C  C     . ALA A 1 30  ? 14.31898  6.87166  21.40476 1.000 26.98538  ? 28  ALA A C     1 
ATOM   257  O  O     . ALA A 1 30  ? 14.28535  8.04702  21.79191 1.000 25.71813  ? 28  ALA A O     1 
ATOM   258  C  CB    . ALA A 1 30  ? 16.53015  5.72523  21.20633 1.000 28.35700  ? 28  ALA A CB    1 
ATOM   259  N  N     . VAL A 1 31  ? 13.52774  6.43035  20.42593 1.000 26.59182  ? 29  VAL A N     1 
ATOM   260  C  CA    . VAL A 1 31  ? 12.53963  7.32180  19.82293 1.000 25.57016  ? 29  VAL A CA    1 
ATOM   261  C  C     . VAL A 1 31  ? 11.47077  7.71690  20.84098 1.000 22.72217  ? 29  VAL A C     1 
ATOM   262  O  O     . VAL A 1 31  ? 11.10057  8.88839  20.94891 1.000 25.17803  ? 29  VAL A O     1 
ATOM   263  C  CB    . VAL A 1 31  ? 11.92304  6.65892  18.58309 1.000 26.12079  ? 29  VAL A CB    1 
ATOM   264  C  CG1   . VAL A 1 31  ? 10.71302  7.45033  18.11939 1.000 28.47833  ? 29  VAL A CG1   1 
ATOM   265  C  CG2   . VAL A 1 31  ? 12.97602  6.56913  17.47705 1.000 26.56967  ? 29  VAL A CG2   1 
ATOM   266  N  N     . LEU A 1 32  ? 10.94413  6.74470  21.59284 1.000 23.67781  ? 30  LEU A N     1 
ATOM   267  C  CA    . LEU A 1 32  ? 9.94674   7.06033  22.60862 1.000 22.42741  ? 30  LEU A CA    1 
ATOM   268  C  C     . LEU A 1 32  ? 10.46688  8.10236  23.59783 1.000 23.63508  ? 30  LEU A C     1 
ATOM   269  O  O     . LEU A 1 32  ? 9.75912   9.05683  23.93909 1.000 21.36996  ? 30  LEU A O     1 
ATOM   270  C  CB    . LEU A 1 32  ? 9.53589   5.78500  23.34840 1.000 23.05931  ? 30  LEU A CB    1 
ATOM   271  C  CG    . LEU A 1 32  ? 8.60765   6.04379  24.54234 1.000 23.96340  ? 30  LEU A CG    1 
ATOM   272  C  CD1   . LEU A 1 32  ? 7.31087   6.66156  24.06067 1.000 24.58645  ? 30  LEU A CD1   1 
ATOM   273  C  CD2   . LEU A 1 32  ? 8.34524   4.75154  25.30222 1.000 25.54800  ? 30  LEU A CD2   1 
ATOM   274  N  N     . VAL A 1 33  ? 11.70510  7.94574  24.07555 1.000 24.29936  ? 31  VAL A N     1 
ATOM   275  C  CA    . VAL A 1 33  ? 12.21456  8.92831  25.02936 1.000 23.41636  ? 31  VAL A CA    1 
ATOM   276  C  C     . VAL A 1 33  ? 12.18945  10.31986 24.41347 1.000 22.22038  ? 31  VAL A C     1 
ATOM   277  O  O     . VAL A 1 33  ? 11.74224  11.28694 25.04362 1.000 22.16892  ? 31  VAL A O     1 
ATOM   278  C  CB    . VAL A 1 33  ? 13.62197  8.54919  25.52395 1.000 25.45967  ? 31  VAL A CB    1 
ATOM   279  C  CG1   . VAL A 1 33  ? 14.17160  9.64906  26.43511 1.000 25.82773  ? 31  VAL A CG1   1 
ATOM   280  C  CG2   . VAL A 1 33  ? 13.57593  7.22935  26.28429 1.000 26.07395  ? 31  VAL A CG2   1 
ATOM   281  N  N     . SER A 1 34  ? 12.65205  10.44565 23.16021 1.000 22.75005  ? 32  SER A N     1 
ATOM   282  C  CA    . SER A 1 34  ? 12.65154  11.76618 22.54075 1.000 21.94447  ? 32  SER A CA    1 
ATOM   283  C  C     . SER A 1 34  ? 11.22743  12.31312 22.40921 1.000 24.28231  ? 32  SER A C     1 
ATOM   284  O  O     . SER A 1 34  ? 10.98592  13.48862 22.69014 1.000 21.50933  ? 32  SER A O     1 
ATOM   285  C  CB    . SER A 1 34  ? 13.37595  11.72607 21.18248 1.000 22.18546  ? 32  SER A CB    1 
ATOM   286  O  OG    . SER A 1 34  ? 12.60393  11.11575 20.15651 1.000 24.51147  ? 32  SER A OG    1 
ATOM   287  N  N     . GLU A 1 35  ? 10.27359  11.47419 21.99373 1.000 22.30375  ? 33  GLU A N     1 
ATOM   288  C  CA    . GLU A 1 35  ? 8.90358   11.94255 21.77911 1.000 24.17992  ? 33  GLU A CA    1 
ATOM   289  C  C     . GLU A 1 35  ? 8.24337   12.37053 23.08916 1.000 23.65542  ? 33  GLU A C     1 
ATOM   290  O  O     . GLU A 1 35  ? 7.52673   13.37500 23.12838 1.000 22.95532  ? 33  GLU A O     1 
ATOM   291  C  CB    . GLU A 1 35  ? 8.09434   10.83918 21.11220 1.000 26.17096  ? 33  GLU A CB    1 
ATOM   292  C  CG    . GLU A 1 35  ? 6.82647   11.25377 20.32052 1.000 30.70864  ? 33  GLU A CG    1 
ATOM   293  C  CD    . GLU A 1 35  ? 7.06234   12.35804 19.24830 1.000 29.64540  ? 33  GLU A CD    1 
ATOM   294  O  OE1   . GLU A 1 35  ? 6.19134   13.26102 19.11562 1.000 31.01294  ? 33  GLU A OE1   1 
ATOM   295  O  OE2   . GLU A 1 35  ? 8.16434   12.36229 18.63199 1.000 32.00112  ? 33  GLU A OE2   1 
ATOM   296  N  N     . VAL A 1 36  ? 8.45763   11.61739 24.16947 1.000 23.14476  ? 34  VAL A N     1 
ATOM   297  C  CA    . VAL A 1 36  ? 7.88706   12.03000 25.44755 1.000 21.39242  ? 34  VAL A CA    1 
ATOM   298  C  C     . VAL A 1 36  ? 8.51053   13.34008 25.88876 1.000 19.50738  ? 34  VAL A C     1 
ATOM   299  O  O     . VAL A 1 36  ? 7.82190   14.25764 26.35914 1.000 21.13093  ? 34  VAL A O     1 
ATOM   300  C  CB    . VAL A 1 36  ? 8.07230   10.92417 26.49591 1.000 22.83438  ? 34  VAL A CB    1 
ATOM   301  C  CG1   . VAL A 1 36  ? 7.64400   11.44556 27.88363 1.000 23.19111  ? 34  VAL A CG1   1 
ATOM   302  C  CG2   . VAL A 1 36  ? 7.26679   9.69960  26.10955 1.000 22.90989  ? 34  VAL A CG2   1 
ATOM   303  N  N     . MET A 1 37  ? 9.83059   13.45070 25.73128 1.000 20.99063  ? 35  MET A N     1 
ATOM   304  C  CA    . MET A 1 37  ? 10.53780  14.65577 26.12053 1.000 18.44739  ? 35  MET A CA    1 
ATOM   305  C  C     . MET A 1 37  ? 10.05381  15.86878 25.32708 1.000 21.69303  ? 35  MET A C     1 
ATOM   306  O  O     . MET A 1 37  ? 10.01533  16.99052 25.85628 1.000 21.64409  ? 35  MET A O     1 
ATOM   307  C  CB    . MET A 1 37  ? 12.02093  14.39782 25.87945 1.000 22.10130  ? 35  MET A CB    1 
ATOM   308  C  CG    . MET A 1 37  ? 12.73976  13.82705 27.06700 1.000 21.23143  ? 35  MET A CG    1 
ATOM   309  S  SD    . MET A 1 37  ? 14.49591  13.80581 26.77054 1.000 23.89166  ? 35  MET A SD    1 
ATOM   310  C  CE    . MET A 1 37  ? 15.05885  13.03848 28.30235 1.000 23.81992  ? 35  MET A CE    1 
ATOM   311  N  N     . LEU A 1 38  ? 9.66600   15.65667 24.06077 1.000 22.51759  ? 36  LEU A N     1 
ATOM   312  C  CA    . LEU A 1 38  ? 9.21256   16.73192 23.18790 1.000 21.09702  ? 36  LEU A CA    1 
ATOM   313  C  C     . LEU A 1 38  ? 7.80219   17.22577 23.48943 1.000 21.31139  ? 36  LEU A C     1 
ATOM   314  O  O     . LEU A 1 38  ? 7.42997   18.29540 22.99694 1.000 23.65985  ? 36  LEU A O     1 
ATOM   315  C  CB    . LEU A 1 38  ? 9.26807   16.27607 21.73125 1.000 19.48791  ? 36  LEU A CB    1 
ATOM   316  C  CG    . LEU A 1 38  ? 10.70435  16.25184 21.21833 1.000 22.93621  ? 36  LEU A CG    1 
ATOM   317  C  CD1   . LEU A 1 38  ? 10.79618  15.36458 19.96196 1.000 24.25364  ? 36  LEU A CD1   1 
ATOM   318  C  CD2   . LEU A 1 38  ? 11.25175  17.66377 20.95379 1.000 24.77773  ? 36  LEU A CD2   1 
ATOM   319  N  N     . GLN A 1 39  ? 7.00625   16.49430 24.27010 1.000 20.31236  ? 37  GLN A N     1 
ATOM   320  C  CA    . GLN A 1 39  ? 5.63492   16.93668 24.54403 1.000 20.16487  ? 37  GLN A CA    1 
ATOM   321  C  C     . GLN A 1 39  ? 5.65563   18.30941 25.21411 1.000 22.59171  ? 37  GLN A C     1 
ATOM   322  O  O     . GLN A 1 39  ? 6.18569   18.46868 26.32197 1.000 22.75399  ? 37  GLN A O     1 
ATOM   323  C  CB    . GLN A 1 39  ? 4.90888   15.91439 25.42873 1.000 21.16182  ? 37  GLN A CB    1 
ATOM   324  C  CG    . GLN A 1 39  ? 4.79906   14.51018 24.82539 1.000 22.51246  ? 37  GLN A CG    1 
ATOM   325  C  CD    . GLN A 1 39  ? 4.25580   13.48872 25.81300 1.000 24.01195  ? 37  GLN A CD    1 
ATOM   326  O  OE1   . GLN A 1 39  ? 3.86653   13.83165 26.94007 1.000 24.91257  ? 37  GLN A OE1   1 
ATOM   327  N  NE2   . GLN A 1 39  ? 4.21262   12.22592 25.39596 1.000 25.13665  ? 37  GLN A NE2   1 
ATOM   328  N  N     . GLN A 1 40  ? 5.07545   19.30543 24.54037 1.000 20.77267  ? 38  GLN A N     1 
ATOM   329  C  CA    . GLN A 1 40  ? 5.01953   20.68016 25.03906 1.000 19.10852  ? 38  GLN A CA    1 
ATOM   330  C  C     . GLN A 1 40  ? 6.39088   21.19893 25.47934 1.000 20.14874  ? 38  GLN A C     1 
ATOM   331  O  O     . GLN A 1 40  ? 6.50705   21.98615 26.42328 1.000 20.57029  ? 38  GLN A O     1 
ATOM   332  C  CB    . GLN A 1 40  ? 3.99501   20.80617 26.17099 1.000 20.94045  ? 38  GLN A CB    1 
ATOM   333  C  CG    . GLN A 1 40  ? 2.57217   20.47451 25.72564 1.000 25.01402  ? 38  GLN A CG    1 
ATOM   334  C  CD    . GLN A 1 40  ? 1.94918   21.59685 24.91485 1.000 25.04432  ? 38  GLN A CD    1 
ATOM   335  O  OE1   . GLN A 1 40  ? 1.30166   22.47661 25.46706 1.000 25.84316  ? 38  GLN A OE1   1 
ATOM   336  N  NE2   . GLN A 1 40  ? 2.17708   21.59196 23.59753 1.000 27.62782  ? 38  GLN A NE2   1 
ATOM   337  N  N     . THR A 1 41  ? 7.43923   20.82351 24.73882 1.000 21.06370  ? 39  THR A N     1 
ATOM   338  C  CA    . THR A 1 41  ? 8.80787   21.20192 25.09282 1.000 18.57266  ? 39  THR A CA    1 
ATOM   339  C  C     . THR A 1 41  ? 9.62297   21.38496 23.81432 1.000 21.71847  ? 39  THR A C     1 
ATOM   340  O  O     . THR A 1 41  ? 9.65215   20.48952 22.96624 1.000 22.83119  ? 39  THR A O     1 
ATOM   341  C  CB    . THR A 1 41  ? 9.47176   20.13937 25.98076 1.000 22.17313  ? 39  THR A CB    1 
ATOM   342  O  OG1   . THR A 1 41  ? 8.60421   19.80160 27.08672 1.000 20.75191  ? 39  THR A OG1   1 
ATOM   343  C  CG2   . THR A 1 41  ? 10.81703  20.64105 26.53742 1.000 23.99658  ? 39  THR A CG2   1 
ATOM   344  N  N     . GLN A 1 42  ? 10.33194  22.50279 23.72175 1.000 21.62513  ? 40  GLN A N     1 
ATOM   345  C  CA    . GLN A 1 42  ? 11.08747  22.83814 22.51273 1.000 22.08093  ? 40  GLN A CA    1 
ATOM   346  C  C     . GLN A 1 42  ? 12.24394  21.87517 22.23071 1.000 26.84487  ? 40  GLN A C     1 
ATOM   347  O  O     . GLN A 1 42  ? 12.92911  21.38124 23.14569 1.000 23.65072  ? 40  GLN A O     1 
ATOM   348  C  CB    . GLN A 1 42  ? 11.64965  24.25102 22.62608 1.000 26.01776  ? 40  GLN A CB    1 
ATOM   349  C  CG    . GLN A 1 42  ? 10.67553  25.36749 22.30952 1.000 24.03122  ? 40  GLN A CG    1 
ATOM   350  C  CD    . GLN A 1 42  ? 11.33671  26.71764 22.49254 1.000 31.27513  ? 40  GLN A CD    1 
ATOM   351  O  OE1   . GLN A 1 42  ? 12.57000  26.83272 22.40873 1.000 38.06331  ? 40  GLN A OE1   1 
ATOM   352  N  NE2   . GLN A 1 42  ? 10.54017  27.75035 22.69618 1.000 31.20642  ? 40  GLN A NE2   1 
ATOM   353  N  N     A VAL A 1 43  ? 12.49274  21.66247 20.93245 0.370 24.96790  ? 41  VAL A N     1 
ATOM   354  N  N     B VAL A 1 43  ? 12.47268  21.64402 20.92979 0.630 24.92584  ? 41  VAL A N     1 
ATOM   355  C  CA    A VAL A 1 43  ? 13.58160  20.79349 20.48014 0.370 25.37093  ? 41  VAL A CA    1 
ATOM   356  C  CA    B VAL A 1 43  ? 13.57364  20.79961 20.45432 0.630 25.30854  ? 41  VAL A CA    1 
ATOM   357  C  C     A VAL A 1 43  ? 14.90599  21.15115 21.14800 0.370 24.36701  ? 41  VAL A C     1 
ATOM   358  C  C     B VAL A 1 43  ? 14.90468  21.15244 21.12087 0.630 24.35475  ? 41  VAL A C     1 
ATOM   359  O  O     A VAL A 1 43  ? 15.67468  20.26467 21.53540 0.370 25.13156  ? 41  VAL A O     1 
ATOM   360  O  O     B VAL A 1 43  ? 15.67527  20.26075 21.48876 0.630 25.08462  ? 41  VAL A O     1 
ATOM   361  C  CB    A VAL A 1 43  ? 13.70466  20.85222 18.94474 0.370 23.44405  ? 41  VAL A CB    1 
ATOM   362  C  CB    B VAL A 1 43  ? 13.67288  20.88974 18.91657 0.630 23.35032  ? 41  VAL A CB    1 
ATOM   363  C  CG1   A VAL A 1 43  ? 12.47021  20.27406 18.28410 0.370 25.82818  ? 41  VAL A CG1   1 
ATOM   364  C  CG1   B VAL A 1 43  ? 15.07586  20.53384 18.44427 0.630 27.86758  ? 41  VAL A CG1   1 
ATOM   365  C  CG2   A VAL A 1 43  ? 13.95371  22.28507 18.48414 0.370 25.71572  ? 41  VAL A CG2   1 
ATOM   366  C  CG2   B VAL A 1 43  ? 12.66501  19.97063 18.26292 0.630 24.89193  ? 41  VAL A CG2   1 
ATOM   367  N  N     . VAL A 1 44  ? 15.21295  22.44729 21.27085 1.000 23.60899  ? 42  VAL A N     1 
ATOM   368  C  CA    . VAL A 1 44  ? 16.51723  22.84218 21.82089 1.000 24.66417  ? 42  VAL A CA    1 
ATOM   369  C  C     . VAL A 1 44  ? 16.66852  22.38734 23.26881 1.000 26.29561  ? 42  VAL A C     1 
ATOM   370  O  O     . VAL A 1 44  ? 17.77485  22.04010 23.71041 1.000 28.56702  ? 42  VAL A O     1 
ATOM   371  C  CB    . VAL A 1 44  ? 16.73346  24.36017 21.69990 1.000 27.84884  ? 42  VAL A CB    1 
ATOM   372  C  CG1   . VAL A 1 44  ? 17.93976  24.78489 22.52452 1.000 37.54973  ? 42  VAL A CG1   1 
ATOM   373  C  CG2   . VAL A 1 44  ? 16.94024  24.73993 20.25431 1.000 35.59500  ? 42  VAL A CG2   1 
ATOM   374  N  N     . ARG A 1 45  ? 15.58223  22.43359 24.04914 1.000 24.67488  ? 43  ARG A N     1 
ATOM   375  C  CA    . ARG A 1 45  ? 15.64983  21.90144 25.40867 1.000 25.82149  ? 43  ARG A CA    1 
ATOM   376  C  C     . ARG A 1 45  ? 15.83711  20.39568 25.39074 1.000 23.93191  ? 43  ARG A C     1 
ATOM   377  O  O     . ARG A 1 45  ? 16.65524  19.85455 26.14371 1.000 25.64449  ? 43  ARG A O     1 
ATOM   378  C  CB    . ARG A 1 45  ? 14.39234  22.26255 26.22168 1.000 25.73990  ? 43  ARG A CB    1 
ATOM   379  C  CG    . ARG A 1 45  ? 14.17325  23.75029 26.42402 1.000 28.35861  ? 43  ARG A CG    1 
ATOM   380  C  CD    . ARG A 1 45  ? 12.77595  23.97240 26.98884 1.000 27.98514  ? 43  ARG A CD    1 
ATOM   381  N  NE    . ARG A 1 45  ? 12.54366  23.42736 28.32248 1.000 27.35147  ? 43  ARG A NE    1 
ATOM   382  C  CZ    . ARG A 1 45  ? 11.43282  23.70209 28.99696 1.000 25.91332  ? 43  ARG A CZ    1 
ATOM   383  N  NH1   . ARG A 1 45  ? 10.40098  24.28655 28.39495 1.000 25.53343  ? 43  ARG A NH1   1 
ATOM   384  N  NH2   . ARG A 1 45  ? 11.33143  23.34242 30.28015 1.000 25.32542  ? 43  ARG A NH2   1 
ATOM   385  N  N     . VAL A 1 46  ? 15.07524  19.69671 24.55093 1.000 22.61125  ? 44  VAL A N     1 
ATOM   386  C  CA    . VAL A 1 46  ? 15.17610  18.24479 24.52280 1.000 21.95505  ? 44  VAL A CA    1 
ATOM   387  C  C     . VAL A 1 46  ? 16.59639  17.82568 24.14678 1.000 27.83616  ? 44  VAL A C     1 
ATOM   388  O  O     . VAL A 1 46  ? 17.13302  16.85189 24.69130 1.000 26.05916  ? 44  VAL A O     1 
ATOM   389  C  CB    . VAL A 1 46  ? 14.11511  17.64635 23.57794 1.000 23.30341  ? 44  VAL A CB    1 
ATOM   390  C  CG1   . VAL A 1 46  ? 14.32416  16.13118 23.41360 1.000 23.89780  ? 44  VAL A CG1   1 
ATOM   391  C  CG2   . VAL A 1 46  ? 12.68695  17.95393 24.10836 1.000 23.24629  ? 44  VAL A CG2   1 
ATOM   392  N  N     . GLY A 1 47  ? 17.24187  18.57910 23.24194 1.000 26.66743  ? 45  GLY A N     1 
ATOM   393  C  CA    . GLY A 1 47  ? 18.62297  18.28889 22.87624 1.000 25.28354  ? 45  GLY A CA    1 
ATOM   394  C  C     . GLY A 1 47  ? 19.59099  18.32693 24.04686 1.000 30.96331  ? 45  GLY A C     1 
ATOM   395  O  O     . GLY A 1 47  ? 20.64259  17.68696 24.00419 1.000 33.20435  ? 45  GLY A O     1 
ATOM   396  N  N     . LYS A 1 48  ? 19.25889  19.08007 25.09683 1.000 25.79733  ? 46  LYS A N     1 
ATOM   397  C  CA    . LYS A 1 48  ? 20.09947  19.15180 26.28460 1.000 27.62173  ? 46  LYS A CA    1 
ATOM   398  C  C     . LYS A 1 48  ? 19.88576  17.98595 27.24306 1.000 26.22243  ? 46  LYS A C     1 
ATOM   399  O  O     . LYS A 1 48  ? 20.72703  17.79090 28.13405 1.000 27.55247  ? 46  LYS A O     1 
ATOM   400  C  CB    . LYS A 1 48  ? 19.85977  20.47807 27.02117 1.000 29.95897  ? 46  LYS A CB    1 
ATOM   401  C  CG    . LYS A 1 48  ? 20.23995  21.70262 26.18681 1.000 31.29364  ? 46  LYS A CG    1 
ATOM   402  C  CD    . LYS A 1 48  ? 20.13887  23.02761 26.94840 1.000 32.15684  ? 46  LYS A CD    1 
ATOM   403  C  CE    . LYS A 1 48  ? 20.41108  24.17342 25.97133 1.000 36.31158  ? 46  LYS A CE    1 
ATOM   404  N  NZ    . LYS A 1 48  ? 20.29743  25.53809 26.55185 1.000 37.92681  ? 46  LYS A NZ    1 
ATOM   405  N  N     . TYR A 1 49  ? 18.81430  17.20614 27.07387 1.000 25.48732  ? 47  TYR A N     1 
ATOM   406  C  CA    . TYR A 1 49  ? 18.47042  16.11578 27.98058 1.000 26.71666  ? 47  TYR A CA    1 
ATOM   407  C  C     . TYR A 1 49  ? 18.51419  14.74350 27.34261 1.000 25.92379  ? 47  TYR A C     1 
ATOM   408  O  O     . TYR A 1 49  ? 18.80107  13.77475 28.04163 1.000 26.23493  ? 47  TYR A O     1 
ATOM   409  C  CB    . TYR A 1 49  ? 17.04696  16.29959 28.56048 1.000 25.13897  ? 47  TYR A CB    1 
ATOM   410  C  CG    . TYR A 1 49  ? 16.97876  17.37954 29.61076 1.000 26.40958  ? 47  TYR A CG    1 
ATOM   411  C  CD1   . TYR A 1 49  ? 16.98174  18.71767 29.24114 1.000 25.84891  ? 47  TYR A CD1   1 
ATOM   412  C  CD2   . TYR A 1 49  ? 16.90800  17.06217 30.96914 1.000 25.49992  ? 47  TYR A CD2   1 
ATOM   413  C  CE1   . TYR A 1 49  ? 16.93633  19.72200 30.18235 1.000 27.86956  ? 47  TYR A CE1   1 
ATOM   414  C  CE2   . TYR A 1 49  ? 16.85166  18.05720 31.92187 1.000 25.26039  ? 47  TYR A CE2   1 
ATOM   415  C  CZ    . TYR A 1 49  ? 16.86379  19.38513 31.52747 1.000 29.34179  ? 47  TYR A CZ    1 
ATOM   416  O  OH    . TYR A 1 49  ? 16.81000  20.38200 32.47174 1.000 29.87665  ? 47  TYR A OH    1 
ATOM   417  N  N     . TRP A 1 50  ? 18.19516  14.62454 26.05126 1.000 23.65267  ? 48  TRP A N     1 
ATOM   418  C  CA    . TRP A 1 50  ? 17.97606  13.30434 25.47063 1.000 23.98548  ? 48  TRP A CA    1 
ATOM   419  C  C     . TRP A 1 50  ? 19.23314  12.43814 25.50198 1.000 26.32962  ? 48  TRP A C     1 
ATOM   420  O  O     . TRP A 1 50  ? 19.18132  11.28597 25.94335 1.000 28.05047  ? 48  TRP A O     1 
ATOM   421  C  CB    . TRP A 1 50  ? 17.46713  13.45513 24.03931 1.000 26.93265  ? 48  TRP A CB    1 
ATOM   422  C  CG    . TRP A 1 50  ? 17.21894  12.16138 23.35852 1.000 24.97273  ? 48  TRP A CG    1 
ATOM   423  C  CD1   . TRP A 1 50  ? 16.14661  11.33280 23.54753 1.000 25.43315  ? 48  TRP A CD1   1 
ATOM   424  C  CD2   . TRP A 1 50  ? 18.02020  11.56036 22.34390 1.000 26.34928  ? 48  TRP A CD2   1 
ATOM   425  N  NE1   . TRP A 1 50  ? 16.24403  10.23680 22.71910 1.000 24.57340  ? 48  TRP A NE1   1 
ATOM   426  C  CE2   . TRP A 1 50  ? 17.38488  10.35533 21.96803 1.000 25.57896  ? 48  TRP A CE2   1 
ATOM   427  C  CE3   . TRP A 1 50  ? 19.22260  11.91243 21.72542 1.000 27.43190  ? 48  TRP A CE3   1 
ATOM   428  C  CZ2   . TRP A 1 50  ? 17.90347  9.51214  20.98716 1.000 26.85399  ? 48  TRP A CZ2   1 
ATOM   429  C  CZ3   . TRP A 1 50  ? 19.73832  11.06722 20.75558 1.000 33.38404  ? 48  TRP A CZ3   1 
ATOM   430  C  CH2   . TRP A 1 50  ? 19.07704  9.87922  20.40137 1.000 28.26074  ? 48  TRP A CH2   1 
ATOM   431  N  N     . ASN A 1 51  ? 20.37590  12.95433 25.00983 1.000 27.61356  ? 49  ASN A N     1 
ATOM   432  C  CA    . ASN A 1 51  ? 21.60132  12.15483 25.01547 1.000 30.50264  ? 49  ASN A CA    1 
ATOM   433  C  C     . ASN A 1 51  ? 21.98843  11.73409 26.42813 1.000 30.11693  ? 49  ASN A C     1 
ATOM   434  O  O     . ASN A 1 51  ? 22.37177  10.58395 26.65988 1.000 28.37227  ? 49  ASN A O     1 
ATOM   435  C  CB    . ASN A 1 51  ? 22.75092  12.93270 24.36620 1.000 31.81042  ? 49  ASN A CB    1 
ATOM   436  C  CG    . ASN A 1 51  ? 22.73055  12.83961 22.84952 1.000 33.09166  ? 49  ASN A CG    1 
ATOM   437  O  OD1   . ASN A 1 51  ? 22.31423  13.77212 22.15728 1.000 36.94786  ? 49  ASN A OD1   1 
ATOM   438  N  ND2   . ASN A 1 51  ? 23.17149  11.70162 22.32359 1.000 36.99943  ? 49  ASN A ND2   1 
ATOM   439  N  N     . ARG A 1 52  ? 21.88091  12.65417 27.38825 1.000 30.27088  ? 50  ARG A N     1 
ATOM   440  C  CA    . ARG A 1 52  ? 22.23104  12.33755 28.76821 1.000 28.83017  ? 50  ARG A CA    1 
ATOM   441  C  C     . ARG A 1 52  ? 21.31939  11.25264 29.32985 1.000 27.83143  ? 50  ARG A C     1 
ATOM   442  O  O     . ARG A 1 52  ? 21.79092  10.31357 29.98931 1.000 29.60445  ? 50  ARG A O     1 
ATOM   443  C  CB    . ARG A 1 52  ? 22.15103  13.60766 29.61739 1.000 34.22504  ? 50  ARG A CB    1 
ATOM   444  C  CG    . ARG A 1 52  ? 22.53430  13.42041 31.08098 1.000 34.01975  ? 50  ARG A CG    1 
ATOM   445  C  CD    . ARG A 1 52  ? 22.44243  14.72851 31.82568 1.000 40.55311  ? 50  ARG A CD    1 
ATOM   446  N  NE    . ARG A 1 52  ? 21.06413  15.02205 32.18533 1.000 38.90793  ? 50  ARG A NE    1 
ATOM   447  C  CZ    . ARG A 1 52  ? 20.69253  15.94431 33.06131 1.000 41.87689  ? 50  ARG A CZ    1 
ATOM   448  N  NH1   . ARG A 1 52  ? 21.57401  16.73882 33.64926 1.000 40.18197  ? 50  ARG A NH1   1 
ATOM   449  N  NH2   . ARG A 1 52  ? 19.40555  16.07071 33.35691 1.000 34.08358  ? 50  ARG A NH2   1 
ATOM   450  N  N     . PHE A 1 53  ? 20.00750  11.36870 29.07352 1.000 26.83215  ? 51  PHE A N     1 
ATOM   451  C  CA    . PHE A 1 53  ? 19.04840  10.38151 29.56808 1.000 27.16128  ? 51  PHE A CA    1 
ATOM   452  C  C     . PHE A 1 53  ? 19.32672  9.01255  28.96160 1.000 29.69892  ? 51  PHE A C     1 
ATOM   453  O  O     . PHE A 1 53  ? 19.35461  7.99764  29.67362 1.000 30.32395  ? 51  PHE A O     1 
ATOM   454  C  CB    . PHE A 1 53  ? 17.61874  10.84656 29.24934 1.000 23.01178  ? 51  PHE A CB    1 
ATOM   455  C  CG    . PHE A 1 53  ? 16.52451  10.02061 29.89327 1.000 23.82966  ? 51  PHE A CG    1 
ATOM   456  C  CD1   . PHE A 1 53  ? 16.13095  8.80638  29.33951 1.000 26.81239  ? 51  PHE A CD1   1 
ATOM   457  C  CD2   . PHE A 1 53  ? 15.84264  10.49536 31.00080 1.000 24.91562  ? 51  PHE A CD2   1 
ATOM   458  C  CE1   . PHE A 1 53  ? 15.10105  8.06112  29.90740 1.000 24.79049  ? 51  PHE A CE1   1 
ATOM   459  C  CE2   . PHE A 1 53  ? 14.79728  9.75257  31.57487 1.000 25.16737  ? 51  PHE A CE2   1 
ATOM   460  C  CZ    . PHE A 1 53  ? 14.43038  8.53583  31.01340 1.000 22.94472  ? 51  PHE A CZ    1 
ATOM   461  N  N     . MET A 1 54  ? 19.55619  8.97471  27.64115 1.000 26.74474  ? 52  MET A N     1 
ATOM   462  C  CA    . MET A 1 54  ? 19.88298  7.72691  26.95932 1.000 28.94637  ? 52  MET A CA    1 
ATOM   463  C  C     . MET A 1 54  ? 21.14930  7.08994  27.53474 1.000 33.44424  ? 52  MET A C     1 
ATOM   464  O  O     . MET A 1 54  ? 21.26231  5.85628  27.60916 1.000 32.76391  ? 52  MET A O     1 
ATOM   465  C  CB    . MET A 1 54  ? 20.05810  8.00625  25.45993 1.000 28.26774  ? 52  MET A CB    1 
ATOM   466  C  CG    . MET A 1 54  ? 18.76065  8.15764  24.63148 1.000 34.07233  ? 52  MET A CG    1 
ATOM   467  S  SD    . MET A 1 54  ? 17.37069  7.11070  25.09743 1.000 29.65383  ? 52  MET A SD    1 
ATOM   468  C  CE    . MET A 1 54  ? 17.94335  5.55004  24.42617 1.000 30.26174  ? 52  MET A CE    1 
ATOM   469  N  N     . GLY A 1 55  ? 22.12997  7.91373  27.91864 1.000 31.03880  ? 53  GLY A N     1 
ATOM   470  C  CA    . GLY A 1 55  ? 23.35738  7.37128  28.48772 1.000 32.46594  ? 53  GLY A CA    1 
ATOM   471  C  C     . GLY A 1 55  ? 23.11822  6.71516  29.83430 1.000 33.91847  ? 53  GLY A C     1 
ATOM   472  O  O     . GLY A 1 55  ? 23.68176  5.66031  30.13442 1.000 36.08875  ? 53  GLY A O     1 
ATOM   473  N  N     . MET A 1 56  ? 22.26176  7.31406  30.65713 1.000 31.63053  ? 54  MET A N     1 
ATOM   474  C  CA    . MET A 1 56  ? 22.03604  6.75196  31.97610 1.000 31.07610  ? 54  MET A CA    1 
ATOM   475  C  C     . MET A 1 56  ? 21.04888  5.59171  31.93968 1.000 30.76961  ? 54  MET A C     1 
ATOM   476  O  O     . MET A 1 56  ? 21.19291  4.63761  32.70826 1.000 34.04798  ? 54  MET A O     1 
ATOM   477  C  CB    . MET A 1 56  ? 21.55941  7.85295  32.92230 1.000 33.36473  ? 54  MET A CB    1 
ATOM   478  C  CG    . MET A 1 56  ? 20.88142  7.33997  34.16804 1.000 42.98066  ? 54  MET A CG    1 
ATOM   479  S  SD    . MET A 1 56  ? 21.18383  8.53673  35.48787 1.000 60.61082  ? 54  MET A SD    1 
ATOM   480  C  CE    . MET A 1 56  ? 22.96301  8.55080  35.33211 1.000 37.13558  ? 54  MET A CE    1 
ATOM   481  N  N     . PHE A 1 57  ? 20.06209  5.63825  31.04433 1.000 29.88584  ? 55  PHE A N     1 
ATOM   482  C  CA    . PHE A 1 57  ? 19.02962  4.60629  30.93276 1.000 31.85197  ? 55  PHE A CA    1 
ATOM   483  C  C     . PHE A 1 57  ? 18.97262  4.15255  29.47834 1.000 30.80148  ? 55  PHE A C     1 
ATOM   484  O  O     . PHE A 1 57  ? 18.07522  4.56181  28.73057 1.000 29.91999  ? 55  PHE A O     1 
ATOM   485  C  CB    . PHE A 1 57  ? 17.66831  5.13185  31.39190 1.000 26.60791  ? 55  PHE A CB    1 
ATOM   486  C  CG    . PHE A 1 57  ? 17.71103  5.90375  32.69707 1.000 28.33123  ? 55  PHE A CG    1 
ATOM   487  C  CD1   . PHE A 1 57  ? 18.07365  5.27539  33.88133 1.000 32.30595  ? 55  PHE A CD1   1 
ATOM   488  C  CD2   . PHE A 1 57  ? 17.39796  7.25078  32.72495 1.000 27.82751  ? 55  PHE A CD2   1 
ATOM   489  C  CE1   . PHE A 1 57  ? 18.10398  5.98946  35.08475 1.000 33.53393  ? 55  PHE A CE1   1 
ATOM   490  C  CE2   . PHE A 1 57  ? 17.41182  7.96823  33.90697 1.000 30.76936  ? 55  PHE A CE2   1 
ATOM   491  C  CZ    . PHE A 1 57  ? 17.76934  7.33631  35.09662 1.000 31.04678  ? 55  PHE A CZ    1 
ATOM   492  N  N     . PRO A 1 58  ? 19.92276  3.31897  29.03894 1.000 33.14335  ? 56  PRO A N     1 
ATOM   493  C  CA    . PRO A 1 58  ? 20.03316  3.02948  27.59282 1.000 32.35016  ? 56  PRO A CA    1 
ATOM   494  C  C     . PRO A 1 58  ? 18.94942  2.11009  27.03971 1.000 32.57982  ? 56  PRO A C     1 
ATOM   495  O  O     . PRO A 1 58  ? 18.83093  2.01745  25.80918 1.000 34.91567  ? 56  PRO A O     1 
ATOM   496  C  CB    . PRO A 1 58  ? 21.41539  2.38072  27.46245 1.000 35.17346  ? 56  PRO A CB    1 
ATOM   497  C  CG    . PRO A 1 58  ? 21.72195  1.83556  28.81817 1.000 31.81031  ? 56  PRO A CG    1 
ATOM   498  C  CD    . PRO A 1 58  ? 21.08071  2.79938  29.79331 1.000 30.58431  ? 56  PRO A CD    1 
ATOM   499  N  N     . THR A 1 59  ? 18.17453  1.42979  27.88561 1.000 32.05786  ? 57  THR A N     1 
ATOM   500  C  CA    . THR A 1 59  ? 17.18251  0.45862  27.44245 1.000 29.88577  ? 57  THR A CA    1 
ATOM   501  C  C     . THR A 1 59  ? 15.94215  0.55324  28.32153 1.000 29.23610  ? 57  THR A C     1 
ATOM   502  O  O     . THR A 1 59  ? 15.97692  1.08329  29.43413 1.000 29.10176  ? 57  THR A O     1 
ATOM   503  C  CB    . THR A 1 59  ? 17.69158  -0.98920 27.51036 1.000 31.26902  ? 57  THR A CB    1 
ATOM   504  O  OG1   . THR A 1 59  ? 17.99925  -1.32379 28.86861 1.000 32.26384  ? 57  THR A OG1   1 
ATOM   505  C  CG2   . THR A 1 59  ? 18.94423  -1.21462 26.61806 1.000 34.41725  ? 57  THR A CG2   1 
ATOM   506  N  N     . ILE A 1 60  ? 14.84600  0.00323  27.79383 1.000 33.22809  ? 58  ILE A N     1 
ATOM   507  C  CA    . ILE A 1 60  ? 13.64010  -0.24522 28.58322 1.000 29.58362  ? 58  ILE A CA    1 
ATOM   508  C  C     . ILE A 1 60  ? 13.98444  -0.90907 29.91590 1.000 31.74943  ? 58  ILE A C     1 
ATOM   509  O  O     . ILE A 1 60  ? 13.52363  -0.48036 30.98054 1.000 31.43209  ? 58  ILE A O     1 
ATOM   510  C  CB    . ILE A 1 60  ? 12.65240  -1.10357 27.76608 1.000 29.03329  ? 58  ILE A CB    1 
ATOM   511  C  CG1   . ILE A 1 60  ? 11.99470  -0.26605 26.66153 1.000 27.99678  ? 58  ILE A CG1   1 
ATOM   512  C  CG2   . ILE A 1 60  ? 11.62018  -1.78540 28.68792 1.000 29.17798  ? 58  ILE A CG2   1 
ATOM   513  C  CD1   . ILE A 1 60  ? 10.85892  0.60348  27.17199 1.000 31.15130  ? 58  ILE A CD1   1 
ATOM   514  N  N     . ASP A 1 61  ? 14.76979  -1.99006 29.87329 1.000 32.67099  ? 59  ASP A N     1 
ATOM   515  C  CA    . ASP A 1 61  ? 15.09659  -2.72231 31.09480 1.000 33.66795  ? 59  ASP A CA    1 
ATOM   516  C  C     . ASP A 1 61  ? 15.89184  -1.85709 32.06448 1.000 31.69042  ? 59  ASP A C     1 
ATOM   517  O  O     . ASP A 1 61  ? 15.70577  -1.94919 33.28664 1.000 32.38009  ? 59  ASP A O     1 
ATOM   518  C  CB    . ASP A 1 61  ? 15.88256  -3.99007 30.75312 1.000 38.59793  ? 59  ASP A CB    1 
ATOM   519  C  CG    . ASP A 1 61  ? 14.98624  -5.15448 30.37902 1.000 39.76067  ? 59  ASP A CG    1 
ATOM   520  O  OD1   . ASP A 1 61  ? 13.75239  -5.06279 30.57251 1.000 40.78987  ? 59  ASP A OD1   1 
ATOM   521  O  OD2   . ASP A 1 61  ? 15.51922  -6.16101 29.87542 1.000 43.82597  ? 59  ASP A OD2   1 
ATOM   522  N  N     . ALA A 1 62  ? 16.79427  -1.01880 31.54157 1.000 31.43151  ? 60  ALA A N     1 
ATOM   523  C  CA    . ALA A 1 62  ? 17.59423  -0.16068 32.41164 1.000 31.38914  ? 60  ALA A CA    1 
ATOM   524  C  C     . ALA A 1 62  ? 16.73409  0.91422  33.05614 1.000 31.20853  ? 60  ALA A C     1 
ATOM   525  O  O     . ALA A 1 62  ? 16.88756  1.20217  34.24932 1.000 31.80414  ? 60  ALA A O     1 
ATOM   526  C  CB    . ALA A 1 62  ? 18.74816  0.47287  31.62897 1.000 32.17627  ? 60  ALA A CB    1 
ATOM   527  N  N     . LEU A 1 63  ? 15.82068  1.51675  32.28648 1.000 28.05574  ? 61  LEU A N     1 
ATOM   528  C  CA    . LEU A 1 63  ? 14.90210  2.48590  32.86867 1.000 25.70231  ? 61  LEU A CA    1 
ATOM   529  C  C     . LEU A 1 63  ? 14.00269  1.83175  33.91335 1.000 30.21955  ? 61  LEU A C     1 
ATOM   530  O  O     . LEU A 1 63  ? 13.71356  2.42568  34.96390 1.000 29.81148  ? 61  LEU A O     1 
ATOM   531  C  CB    . LEU A 1 63  ? 14.06091  3.13013  31.76374 1.000 23.26468  ? 61  LEU A CB    1 
ATOM   532  C  CG    . LEU A 1 63  ? 13.08737  4.20401  32.24629 1.000 24.41321  ? 61  LEU A CG    1 
ATOM   533  C  CD1   . LEU A 1 63  ? 13.82333  5.27083  33.03223 1.000 27.58459  ? 61  LEU A CD1   1 
ATOM   534  C  CD2   . LEU A 1 63  ? 12.38294  4.85095  31.05388 1.000 25.10091  ? 61  LEU A CD2   1 
ATOM   535  N  N     . ALA A 1 64  ? 13.53805  0.61026  33.63693 1.000 29.73907  ? 62  ALA A N     1 
ATOM   536  C  CA    . ALA A 1 64  ? 12.68278  -0.09040 34.58972 1.000 31.41847  ? 62  ALA A CA    1 
ATOM   537  C  C     . ALA A 1 64  ? 13.40973  -0.34309 35.90208 1.000 32.83396  ? 62  ALA A C     1 
ATOM   538  O  O     . ALA A 1 64  ? 12.82461  -0.20499 36.98277 1.000 33.54791  ? 62  ALA A O     1 
ATOM   539  C  CB    . ALA A 1 64  ? 12.20646  -1.41044 33.99180 1.000 32.26700  ? 62  ALA A CB    1 
ATOM   540  N  N     . ALA A 1 65  ? 14.68726  -0.72117 35.82258 1.000 29.75775  ? 63  ALA A N     1 
ATOM   541  C  CA    . ALA A 1 65  ? 15.46935  -1.08493 36.99794 1.000 33.54725  ? 63  ALA A CA    1 
ATOM   542  C  C     . ALA A 1 65  ? 15.91494  0.12218  37.81015 1.000 32.59042  ? 63  ALA A C     1 
ATOM   543  O  O     . ALA A 1 65  ? 16.21932  -0.02587 38.99956 1.000 34.09282  ? 63  ALA A O     1 
ATOM   544  C  CB    . ALA A 1 65  ? 16.69406  -1.89406 36.56701 1.000 34.44648  ? 63  ALA A CB    1 
ATOM   545  N  N     . ALA A 1 66  ? 15.95424  1.30069  37.19796 1.000 31.86630  ? 64  ALA A N     1 
ATOM   546  C  CA    . ALA A 1 66  ? 16.43652  2.50091  37.86012 1.000 32.35380  ? 64  ALA A CA    1 
ATOM   547  C  C     . ALA A 1 66  ? 15.53405  2.86728  39.02979 1.000 34.10494  ? 64  ALA A C     1 
ATOM   548  O  O     . ALA A 1 66  ? 14.37372  2.45286  39.10835 1.000 30.58781  ? 64  ALA A O     1 
ATOM   549  C  CB    . ALA A 1 66  ? 16.49178  3.66549  36.86891 1.000 33.05074  ? 64  ALA A CB    1 
ATOM   550  N  N     . SER A 1 67  ? 16.08408  3.64963  39.95469 1.000 35.77090  ? 65  SER A N     1 
ATOM   551  C  CA    . SER A 1 67  ? 15.24666  4.23989  40.98661 1.000 31.64740  ? 65  SER A CA    1 
ATOM   552  C  C     . SER A 1 67  ? 14.43333  5.38649  40.39770 1.000 29.93079  ? 65  SER A C     1 
ATOM   553  O  O     . SER A 1 67  ? 14.86812  6.08326  39.47333 1.000 30.46054  ? 65  SER A O     1 
ATOM   554  C  CB    . SER A 1 67  ? 16.09655  4.73154  42.16304 1.000 33.86773  ? 65  SER A CB    1 
ATOM   555  O  OG    . SER A 1 67  ? 16.74295  5.96013  41.87328 1.000 36.00184  ? 65  SER A OG    1 
ATOM   556  N  N     . THR A 1 68  ? 13.22265  5.56643  40.93316 1.000 32.15504  ? 66  THR A N     1 
ATOM   557  C  CA    . THR A 1 68  ? 12.39478  6.67882  40.48857 1.000 31.43937  ? 66  THR A CA    1 
ATOM   558  C  C     . THR A 1 68  ? 13.08209  8.00990  40.77441 1.000 28.42362  ? 66  THR A C     1 
ATOM   559  O  O     . THR A 1 68  ? 13.02710  8.93538  39.95786 1.000 26.58270  ? 66  THR A O     1 
ATOM   560  C  CB    . THR A 1 68  ? 11.02636  6.58163  41.15979 1.000 33.81008  ? 66  THR A CB    1 
ATOM   561  O  OG1   . THR A 1 68  ? 10.41368  5.34340  40.76913 1.000 35.68657  ? 66  THR A OG1   1 
ATOM   562  C  CG2   . THR A 1 68  ? 10.12793  7.74920  40.74898 1.000 35.42209  ? 66  THR A CG2   1 
ATOM   563  N  N     . ALA A 1 69  ? 13.76826  8.11246  41.91603 1.000 27.77781  ? 67  ALA A N     1 
ATOM   564  C  CA    . ALA A 1 69  ? 14.49160  9.33872  42.24354 1.000 27.46969  ? 67  ALA A CA    1 
ATOM   565  C  C     . ALA A 1 69  ? 15.52066  9.69064  41.17618 1.000 29.29817  ? 67  ALA A C     1 
ATOM   566  O  O     . ALA A 1 69  ? 15.66720  10.86317 40.81520 1.000 31.22079  ? 67  ALA A O     1 
ATOM   567  C  CB    . ALA A 1 69  ? 15.18457  9.19943  43.60543 1.000 30.58562  ? 67  ALA A CB    1 
ATOM   568  N  N     . ASP A 1 70  ? 16.26501  8.69845  40.67978 1.000 29.56470  ? 68  ASP A N     1 
ATOM   569  C  CA    . ASP A 1 70  ? 17.23465  8.98799  39.62558 1.000 29.70242  ? 68  ASP A CA    1 
ATOM   570  C  C     . ASP A 1 70  ? 16.54937  9.47346  38.35617 1.000 30.18410  ? 68  ASP A C     1 
ATOM   571  O  O     . ASP A 1 70  ? 17.05959  10.37674 37.68153 1.000 27.31192  ? 68  ASP A O     1 
ATOM   572  C  CB    . ASP A 1 70  ? 18.09417  7.76124  39.30738 1.000 31.11074  ? 68  ASP A CB    1 
ATOM   573  C  CG    . ASP A 1 70  ? 19.17844  7.51989  40.33851 1.000 36.08047  ? 68  ASP A CG    1 
ATOM   574  O  OD1   . ASP A 1 70  ? 19.41646  8.40574  41.18895 1.000 39.84938  ? 68  ASP A OD1   1 
ATOM   575  O  OD2   . ASP A 1 70  ? 19.79117  6.43933  40.28888 1.000 39.95629  ? 68  ASP A OD2   1 
ATOM   576  N  N     . VAL A 1 71  ? 15.41385  8.86968  37.99488 1.000 26.59491  ? 69  VAL A N     1 
ATOM   577  C  CA    . VAL A 1 71  ? 14.71319  9.30679  36.78763 1.000 26.10244  ? 69  VAL A CA    1 
ATOM   578  C  C     . VAL A 1 71  ? 14.20908  10.73284 36.96067 1.000 26.16640  ? 69  VAL A C     1 
ATOM   579  O  O     . VAL A 1 71  ? 14.38527  11.57837 36.07525 1.000 26.82436  ? 69  VAL A O     1 
ATOM   580  C  CB    . VAL A 1 71  ? 13.57612  8.32915  36.44583 1.000 26.39724  ? 69  VAL A CB    1 
ATOM   581  C  CG1   . VAL A 1 71  ? 12.83159  8.80087  35.18871 1.000 26.09756  ? 69  VAL A CG1   1 
ATOM   582  C  CG2   . VAL A 1 71  ? 14.14379  6.93958  36.22393 1.000 28.77180  ? 69  VAL A CG2   1 
ATOM   583  N  N     . LEU A 1 72  ? 13.61836  11.03977 38.12588 1.000 24.45060  ? 70  LEU A N     1 
ATOM   584  C  CA    . LEU A 1 72  ? 13.15345  12.40269 38.38078 1.000 25.71112  ? 70  LEU A CA    1 
ATOM   585  C  C     . LEU A 1 72  ? 14.30745  13.40243 38.36900 1.000 25.26996  ? 70  LEU A C     1 
ATOM   586  O  O     . LEU A 1 72  ? 14.15994  14.51904 37.85617 1.000 26.95935  ? 70  LEU A O     1 
ATOM   587  C  CB    . LEU A 1 72  ? 12.40043  12.46494 39.71325 1.000 26.70812  ? 70  LEU A CB    1 
ATOM   588  C  CG    . LEU A 1 72  ? 11.04327  11.76737 39.75307 1.000 25.01623  ? 70  LEU A CG    1 
ATOM   589  C  CD1   . LEU A 1 72  ? 10.51700  11.74828 41.20160 1.000 26.04693  ? 70  LEU A CD1   1 
ATOM   590  C  CD2   . LEU A 1 72  ? 10.04636  12.46165 38.81991 1.000 26.13981  ? 70  LEU A CD2   1 
ATOM   591  N  N     . ALA A 1 73  ? 15.45848  13.03326 38.95278 1.000 26.85539  ? 71  ALA A N     1 
ATOM   592  C  CA    . ALA A 1 73  ? 16.62326  13.92024 38.93240 1.000 30.87375  ? 71  ALA A CA    1 
ATOM   593  C  C     . ALA A 1 73  ? 17.04772  14.24582 37.50614 1.000 28.76661  ? 71  ALA A C     1 
ATOM   594  O  O     . ALA A 1 73  ? 17.38535  15.39396 37.19596 1.000 28.48868  ? 71  ALA A O     1 
ATOM   595  C  CB    . ALA A 1 73  ? 17.79255  13.28475 39.69635 1.000 31.03557  ? 71  ALA A CB    1 
ATOM   596  N  N     . GLN A 1 74  ? 17.04636  13.23977 36.62880 1.000 25.62412  ? 72  GLN A N     1 
ATOM   597  C  CA    . GLN A 1 74  ? 17.40628  13.44455 35.23129 1.000 28.50580  ? 72  GLN A CA    1 
ATOM   598  C  C     . GLN A 1 74  ? 16.42086  14.35368 34.51537 1.000 26.50053  ? 72  GLN A C     1 
ATOM   599  O  O     . GLN A 1 74  ? 16.80695  15.07646 33.59090 1.000 29.16745  ? 72  GLN A O     1 
ATOM   600  C  CB    . GLN A 1 74  ? 17.48738  12.09080 34.53255 1.000 32.79659  ? 72  GLN A CB    1 
ATOM   601  C  CG    . GLN A 1 74  ? 18.77158  11.32746 34.80946 1.000 34.37950  ? 72  GLN A CG    1 
ATOM   602  C  CD    . GLN A 1 74  ? 19.90698  11.92359 34.00948 1.000 39.76706  ? 72  GLN A CD    1 
ATOM   603  O  OE1   . GLN A 1 74  ? 19.82257  12.00425 32.77653 1.000 41.09412  ? 72  GLN A OE1   1 
ATOM   604  N  NE2   . GLN A 1 74  ? 20.95807  12.34630 34.68306 1.000 41.08592  ? 72  GLN A NE2   1 
ATOM   605  N  N     . TRP A 1 75  ? 15.16040  14.34211 34.93448 1.000 22.95356  ? 73  TRP A N     1 
ATOM   606  C  CA    . TRP A 1 75  ? 14.11348  15.09485 34.25362 1.000 23.65569  ? 73  TRP A CA    1 
ATOM   607  C  C     . TRP A 1 75  ? 14.09385  16.56662 34.62920 1.000 23.20007  ? 73  TRP A C     1 
ATOM   608  O  O     . TRP A 1 75  ? 13.58792  17.38720 33.84896 1.000 24.73817  ? 73  TRP A O     1 
ATOM   609  C  CB    . TRP A 1 75  ? 12.74423  14.49408 34.59107 1.000 22.31319  ? 73  TRP A CB    1 
ATOM   610  C  CG    . TRP A 1 75  ? 11.70402  14.79100 33.57334 1.000 20.34200  ? 73  TRP A CG    1 
ATOM   611  C  CD1   . TRP A 1 75  ? 10.72260  15.75496 33.63575 1.000 23.51228  ? 73  TRP A CD1   1 
ATOM   612  C  CD2   . TRP A 1 75  ? 11.51741  14.10096 32.34791 1.000 21.65413  ? 73  TRP A CD2   1 
ATOM   613  N  NE1   . TRP A 1 75  ? 9.94380   15.70263 32.48341 1.000 23.37897  ? 73  TRP A NE1   1 
ATOM   614  C  CE2   . TRP A 1 75  ? 10.41802  14.69701 31.68242 1.000 22.31888  ? 73  TRP A CE2   1 
ATOM   615  C  CE3   . TRP A 1 75  ? 12.18075  13.03565 31.73363 1.000 23.93402  ? 73  TRP A CE3   1 
ATOM   616  C  CZ2   . TRP A 1 75  ? 9.96815   14.25034 30.44418 1.000 23.09712  ? 73  TRP A CZ2   1 
ATOM   617  C  CZ3   . TRP A 1 75  ? 11.72890  12.59757 30.48788 1.000 23.69579  ? 73  TRP A CZ3   1 
ATOM   618  C  CH2   . TRP A 1 75  ? 10.63375  13.20318 29.86568 1.000 22.98469  ? 73  TRP A CH2   1 
ATOM   619  N  N     A GLN A 1 76  ? 14.61428  16.91960 35.79890 0.800 24.62172  ? 74  GLN A N     1 
ATOM   620  N  N     B GLN A 1 76  ? 14.60141  16.90983 35.81260 0.200 24.65687  ? 74  GLN A N     1 
ATOM   621  C  CA    A GLN A 1 76  ? 14.37301  18.24403 36.34748 0.800 25.68879  ? 74  GLN A CA    1 
ATOM   622  C  CA    B GLN A 1 76  ? 14.48131  18.25891 36.35256 0.200 25.70921  ? 74  GLN A CA    1 
ATOM   623  C  C     A GLN A 1 76  ? 14.84713  19.32138 35.39025 0.800 25.66508  ? 74  GLN A C     1 
ATOM   624  C  C     B GLN A 1 76  ? 14.85303  19.30368 35.31569 0.200 25.76328  ? 74  GLN A C     1 
ATOM   625  O  O     A GLN A 1 76  ? 16.00676  19.32310 34.95891 0.800 25.42509  ? 74  GLN A O     1 
ATOM   626  O  O     B GLN A 1 76  ? 15.95435  19.27570 34.75763 0.200 25.53844  ? 74  GLN A O     1 
ATOM   627  C  CB    A GLN A 1 76  ? 15.05102  18.37821 37.70968 0.800 25.17036  ? 74  GLN A CB    1 
ATOM   628  C  CB    B GLN A 1 76  ? 15.37170  18.39880 37.58864 0.200 25.71509  ? 74  GLN A CB    1 
ATOM   629  C  CG    A GLN A 1 76  ? 14.39697  17.50409 38.77197 0.800 27.33742  ? 74  GLN A CG    1 
ATOM   630  C  CG    B GLN A 1 76  ? 14.86063  19.38170 38.62348 0.200 28.83717  ? 74  GLN A CG    1 
ATOM   631  C  CD    A GLN A 1 76  ? 12.88441  17.67965 38.81434 0.800 30.36592  ? 74  GLN A CD    1 
ATOM   632  C  CD    B GLN A 1 76  ? 15.71121  19.38386 39.87787 0.200 29.85637  ? 74  GLN A CD    1 
ATOM   633  O  OE1   A GLN A 1 76  ? 12.39396  18.75950 39.13042 0.800 31.19079  ? 74  GLN A OE1   1 
ATOM   634  O  OE1   B GLN A 1 76  ? 15.35234  18.77121 40.88387 0.200 33.94757  ? 74  GLN A OE1   1 
ATOM   635  N  NE2   A GLN A 1 76  ? 12.14086  16.61987 38.48417 0.800 29.41797  ? 74  GLN A NE2   1 
ATOM   636  N  NE2   B GLN A 1 76  ? 16.85269  20.06411 39.82132 0.200 27.14271  ? 74  GLN A NE2   1 
ATOM   637  N  N     . GLY A 1 77  ? 13.93092  20.23199 35.05964 1.000 25.96182  ? 75  GLY A N     1 
ATOM   638  C  CA    . GLY A 1 77  ? 14.15843  21.29941 34.11375 1.000 26.01975  ? 75  GLY A CA    1 
ATOM   639  C  C     . GLY A 1 77  ? 13.36227  21.15020 32.84282 1.000 24.57208  ? 75  GLY A C     1 
ATOM   640  O  O     . GLY A 1 77  ? 13.11140  22.15657 32.16292 1.000 26.15282  ? 75  GLY A O     1 
ATOM   641  N  N     . LEU A 1 78  ? 12.92268  19.92631 32.52069 1.000 22.57859  ? 76  LEU A N     1 
ATOM   642  C  CA    . LEU A 1 78  ? 12.07749  19.71267 31.34820 1.000 21.43903  ? 76  LEU A CA    1 
ATOM   643  C  C     . LEU A 1 78  ? 10.62451  20.11256 31.58607 1.000 24.17819  ? 76  LEU A C     1 
ATOM   644  O  O     . LEU A 1 78  ? 9.90341   20.37835 30.61448 1.000 21.76212  ? 76  LEU A O     1 
ATOM   645  C  CB    . LEU A 1 78  ? 12.12206  18.24758 30.90762 1.000 20.80814  ? 76  LEU A CB    1 
ATOM   646  C  CG    . LEU A 1 78  ? 13.38041  17.82294 30.12565 1.000 22.68344  ? 76  LEU A CG    1 
ATOM   647  C  CD1   . LEU A 1 78  ? 13.41194  16.31235 29.92424 1.000 22.19769  ? 76  LEU A CD1   1 
ATOM   648  C  CD2   . LEU A 1 78  ? 13.37880  18.52211 28.76730 1.000 23.84206  ? 76  LEU A CD2   1 
ATOM   649  N  N     . GLY A 1 79  ? 10.16799  20.16709 32.83622 1.000 25.07791  ? 77  GLY A N     1 
ATOM   650  C  CA    . GLY A 1 79  ? 8.78448   20.50571 33.12083 1.000 23.11919  ? 77  GLY A CA    1 
ATOM   651  C  C     . GLY A 1 79  ? 7.85152   19.32255 32.93182 1.000 23.28688  ? 77  GLY A C     1 
ATOM   652  O  O     . GLY A 1 79  ? 8.23024   18.24554 32.45659 1.000 21.93244  ? 77  GLY A O     1 
ATOM   653  N  N     . TYR A 1 80  ? 6.58896   19.54598 33.28518 1.000 22.56176  ? 78  TYR A N     1 
ATOM   654  C  CA    . TYR A 1 80  ? 5.53941   18.52707 33.20153 1.000 23.71964  ? 78  TYR A CA    1 
ATOM   655  C  C     . TYR A 1 80  ? 6.08595   17.16558 33.64511 1.000 23.25622  ? 78  TYR A C     1 
ATOM   656  O  O     . TYR A 1 80  ? 6.19074   16.19206 32.88771 1.000 21.27625  ? 78  TYR A O     1 
ATOM   657  C  CB    . TYR A 1 80  ? 4.92439   18.48298 31.79981 1.000 22.21076  ? 78  TYR A CB    1 
ATOM   658  C  CG    . TYR A 1 80  ? 3.94271   19.61365 31.50254 1.000 25.17930  ? 78  TYR A CG    1 
ATOM   659  C  CD1   . TYR A 1 80  ? 3.51692   20.48371 32.48775 1.000 24.92783  ? 78  TYR A CD1   1 
ATOM   660  C  CD2   . TYR A 1 80  ? 3.46231   19.81676 30.21417 1.000 22.22100  ? 78  TYR A CD2   1 
ATOM   661  C  CE1   . TYR A 1 80  ? 2.61529   21.51387 32.22361 1.000 24.55744  ? 78  TYR A CE1   1 
ATOM   662  C  CE2   . TYR A 1 80  ? 2.57152   20.83868 29.93144 1.000 21.02069  ? 78  TYR A CE2   1 
ATOM   663  C  CZ    . TYR A 1 80  ? 2.14159   21.68683 30.93710 1.000 22.99819  ? 78  TYR A CZ    1 
ATOM   664  O  OH    . TYR A 1 80  ? 1.24383   22.70936 30.68817 1.000 25.27898  ? 78  TYR A OH    1 
ATOM   665  N  N     . ASN A 1 81  ? 6.44283   17.13348 34.93188 1.000 23.17298  ? 79  ASN A N     1 
ATOM   666  C  CA    . ASN A 1 81  ? 7.21928   16.04147 35.50486 1.000 24.21582  ? 79  ASN A CA    1 
ATOM   667  C  C     . ASN A 1 81  ? 6.43825   14.73388 35.62346 1.000 22.85777  ? 79  ASN A C     1 
ATOM   668  O  O     . ASN A 1 81  ? 7.05586   13.68476 35.82628 1.000 22.97927  ? 79  ASN A O     1 
ATOM   669  C  CB    . ASN A 1 81  ? 7.75460   16.47868 36.87164 1.000 24.15629  ? 79  ASN A CB    1 
ATOM   670  C  CG    . ASN A 1 81  ? 8.63375   17.71667 36.77963 1.000 27.43980  ? 79  ASN A CG    1 
ATOM   671  O  OD1   . ASN A 1 81  ? 9.74106   17.65277 36.24402 1.000 27.99670  ? 79  ASN A OD1   1 
ATOM   672  N  ND2   . ASN A 1 81  ? 8.14740   18.84957 37.29216 1.000 25.45429  ? 79  ASN A ND2   1 
ATOM   673  N  N     . ARG A 1 82  ? 5.10290   14.75500 35.51001 1.000 19.39886  ? 80  ARG A N     1 
ATOM   674  C  CA    . ARG A 1 82  ? 4.39204   13.48489 35.40378 1.000 24.34777  ? 80  ARG A CA    1 
ATOM   675  C  C     . ARG A 1 82  ? 4.92546   12.64808 34.24777 1.000 23.50574  ? 80  ARG A C     1 
ATOM   676  O  O     . ARG A 1 82  ? 4.81783   11.41774 34.28225 1.000 22.59916  ? 80  ARG A O     1 
ATOM   677  C  CB    . ARG A 1 82  ? 2.88581   13.70806 35.20790 1.000 23.18726  ? 80  ARG A CB    1 
ATOM   678  C  CG    . ARG A 1 82  ? 2.17068   14.20560 36.42201 1.000 25.56813  ? 80  ARG A CG    1 
ATOM   679  C  CD    . ARG A 1 82  ? 0.79658   14.73214 36.02415 1.000 27.22918  ? 80  ARG A CD    1 
ATOM   680  N  NE    . ARG A 1 82  ? -0.03543  15.00436 37.18684 1.000 28.78005  ? 80  ARG A NE    1 
ATOM   681  C  CZ    . ARG A 1 82  ? -1.22995  15.57691 37.12092 1.000 30.34535  ? 80  ARG A CZ    1 
ATOM   682  N  NH1   . ARG A 1 82  ? -1.74772  15.95822 35.95745 1.000 31.85737  ? 80  ARG A NH1   1 
ATOM   683  N  NH2   . ARG A 1 82  ? -1.91070  15.78982 38.24589 1.000 33.45426  ? 80  ARG A NH2   1 
ATOM   684  N  N     . ARG A 1 83  ? 5.47477   13.29724 33.20559 1.000 21.09472  ? 81  ARG A N     1 
ATOM   685  C  CA    . ARG A 1 83  ? 5.99972   12.55554 32.06178 1.000 21.76316  ? 81  ARG A CA    1 
ATOM   686  C  C     . ARG A 1 83  ? 7.09228   11.58687 32.48112 1.000 23.47534  ? 81  ARG A C     1 
ATOM   687  O  O     . ARG A 1 83  ? 7.20229   10.49130 31.92707 1.000 23.28209  ? 81  ARG A O     1 
ATOM   688  C  CB    . ARG A 1 83  ? 6.54546   13.52287 31.01209 1.000 20.88297  ? 81  ARG A CB    1 
ATOM   689  C  CG    . ARG A 1 83  ? 5.45842   14.40020 30.39808 1.000 19.96789  ? 81  ARG A CG    1 
ATOM   690  C  CD    . ARG A 1 83  ? 6.09186   15.23730 29.29986 1.000 22.85597  ? 81  ARG A CD    1 
ATOM   691  N  NE    . ARG A 1 83  ? 6.99463   16.25887 29.84005 1.000 21.55713  ? 81  ARG A NE    1 
ATOM   692  C  CZ    . ARG A 1 83  ? 7.85169   16.93578 29.08882 1.000 22.60133  ? 81  ARG A CZ    1 
ATOM   693  N  NH1   . ARG A 1 83  ? 8.08007   16.59617 27.82927 1.000 21.27885  ? 81  ARG A NH1   1 
ATOM   694  N  NH2   . ARG A 1 83  ? 8.46726   17.99464 29.59715 1.000 22.71941  ? 81  ARG A NH2   1 
ATOM   695  N  N     . ALA A 1 84  ? 7.92357   11.98059 33.45012 1.000 22.67234  ? 82  ALA A N     1 
ATOM   696  C  CA    . ALA A 1 84  ? 9.02650   11.12359 33.87871 1.000 24.57727  ? 82  ALA A CA    1 
ATOM   697  C  C     . ALA A 1 84  ? 8.49584   9.85902  34.53112 1.000 25.07683  ? 82  ALA A C     1 
ATOM   698  O  O     . ALA A 1 84  ? 8.98980   8.75871  34.26235 1.000 24.34658  ? 82  ALA A O     1 
ATOM   699  C  CB    . ALA A 1 84  ? 9.92918   11.88082 34.85421 1.000 24.07118  ? 82  ALA A CB    1 
ATOM   700  N  N     . LEU A 1 85  ? 7.47305   10.00185 35.38283 1.000 22.73186  ? 83  LEU A N     1 
ATOM   701  C  CA    . LEU A 1 85  ? 6.88108   8.83973  36.02783 1.000 25.31861  ? 83  LEU A CA    1 
ATOM   702  C  C     . LEU A 1 85  ? 6.19579   7.94293  35.00948 1.000 26.42560  ? 83  LEU A C     1 
ATOM   703  O  O     . LEU A 1 85  ? 6.28446   6.71459  35.10229 1.000 26.04520  ? 83  LEU A O     1 
ATOM   704  C  CB    . LEU A 1 85  ? 5.87940   9.27455  37.10214 1.000 25.66765  ? 83  LEU A CB    1 
ATOM   705  C  CG    . LEU A 1 85  ? 6.42559   10.10721 38.25815 1.000 27.98925  ? 83  LEU A CG    1 
ATOM   706  C  CD1   . LEU A 1 85  ? 5.29392   10.41999 39.24816 1.000 26.56755  ? 83  LEU A CD1   1 
ATOM   707  C  CD2   . LEU A 1 85  ? 7.57192   9.39352  38.97990 1.000 28.11672  ? 83  LEU A CD2   1 
ATOM   708  N  N     . ALA A 1 86  ? 5.47112   8.53283  34.05236 1.000 22.21801  ? 84  ALA A N     1 
ATOM   709  C  CA    . ALA A 1 86  ? 4.74594   7.69824  33.10486 1.000 24.32449  ? 84  ALA A CA    1 
ATOM   710  C  C     . ALA A 1 86  ? 5.70469   6.96493  32.17968 1.000 22.46161  ? 84  ALA A C     1 
ATOM   711  O  O     . ALA A 1 86  ? 5.49029   5.78923  31.85791 1.000 26.04815  ? 84  ALA A O     1 
ATOM   712  C  CB    . ALA A 1 86  ? 3.75565   8.54762  32.30322 1.000 26.01722  ? 84  ALA A CB    1 
ATOM   713  N  N     . LEU A 1 87  ? 6.75419   7.65074  31.73122 1.000 22.16556  ? 85  LEU A N     1 
ATOM   714  C  CA    . LEU A 1 87  ? 7.77610   7.00273  30.91437 1.000 23.44323  ? 85  LEU A CA    1 
ATOM   715  C  C     . LEU A 1 87  ? 8.41972   5.84842  31.67351 1.000 25.68630  ? 85  LEU A C     1 
ATOM   716  O  O     . LEU A 1 87  ? 8.59629   4.74674  31.13386 1.000 25.87026  ? 85  LEU A O     1 
ATOM   717  C  CB    . LEU A 1 87  ? 8.81562   8.03789  30.49651 1.000 24.06533  ? 85  LEU A CB    1 
ATOM   718  C  CG    . LEU A 1 87  ? 10.00511  7.56648  29.65339 1.000 23.97862  ? 85  LEU A CG    1 
ATOM   719  C  CD1   . LEU A 1 87  ? 9.53533   6.84086  28.36659 1.000 25.82623  ? 85  LEU A CD1   1 
ATOM   720  C  CD2   . LEU A 1 87  ? 10.89898  8.75803  29.31600 1.000 26.33778  ? 85  LEU A CD2   1 
ATOM   721  N  N     . LYS A 1 88  ? 8.76856   6.07306  32.94292 1.000 23.77507  ? 86  LYS A N     1 
ATOM   722  C  CA    . LYS A 1 88  ? 9.37530   4.98521  33.70110 1.000 25.32348  ? 86  LYS A CA    1 
ATOM   723  C  C     . LYS A 1 88  ? 8.39756   3.83478  33.88298 1.000 27.83228  ? 86  LYS A C     1 
ATOM   724  O  O     . LYS A 1 88  ? 8.78173   2.66187  33.77760 1.000 27.90747  ? 86  LYS A O     1 
ATOM   725  C  CB    . LYS A 1 88  ? 9.87508   5.48442  35.04941 1.000 27.44021  ? 86  LYS A CB    1 
ATOM   726  C  CG    . LYS A 1 88  ? 10.78472  4.47320  35.73192 1.000 30.11551  ? 86  LYS A CG    1 
ATOM   727  C  CD    . LYS A 1 88  ? 10.97782  4.82721  37.19305 1.000 26.49909  ? 86  LYS A CD    1 
ATOM   728  C  CE    . LYS A 1 88  ? 12.12667  4.01789  37.83801 1.000 32.75681  ? 86  LYS A CE    1 
ATOM   729  N  NZ    . LYS A 1 88  ? 12.19477  2.59324  37.39305 1.000 31.24787  ? 86  LYS A NZ    1 
ATOM   730  N  N     . ARG A 1 89  ? 7.12547   4.14983  34.16073 1.000 27.15437  ? 87  ARG A N     1 
ATOM   731  C  CA    . ARG A 1 89  ? 6.12642   3.09960  34.32504 1.000 29.68499  ? 87  ARG A CA    1 
ATOM   732  C  C     . ARG A 1 89  ? 5.99822   2.28474  33.05381 1.000 29.25011  ? 87  ARG A C     1 
ATOM   733  O  O     . ARG A 1 89  ? 5.86423   1.05863  33.10543 1.000 29.87604  ? 87  ARG A O     1 
ATOM   734  C  CB    . ARG A 1 89  ? 4.76334   3.69526  34.68303 1.000 31.04888  ? 87  ARG A CB    1 
ATOM   735  C  CG    . ARG A 1 89  ? 4.18648   3.29823  36.01712 1.000 53.22674  ? 87  ARG A CG    1 
ATOM   736  C  CD    . ARG A 1 89  ? 2.97527   4.18605  36.31536 1.000 55.25587  ? 87  ARG A CD    1 
ATOM   737  N  NE    . ARG A 1 89  ? 3.22918   5.19174  37.33896 1.000 52.91095  ? 87  ARG A NE    1 
ATOM   738  C  CZ    . ARG A 1 89  ? 2.77145   6.43562  37.28840 1.000 55.35632  ? 87  ARG A CZ    1 
ATOM   739  N  NH1   . ARG A 1 89  ? 2.10209   6.88392  36.23560 1.000 57.27687  ? 87  ARG A NH1   1 
ATOM   740  N  NH2   . ARG A 1 89  ? 3.00551   7.25494  38.31051 1.000 55.09775  ? 87  ARG A NH2   1 
ATOM   741  N  N     . THR A 1 90  ? 5.99545   2.95849  31.90177 1.000 26.24471  ? 88  THR A N     1 
ATOM   742  C  CA    . THR A 1 90  ? 5.91962   2.23971  30.63631 1.000 27.57651  ? 88  THR A CA    1 
ATOM   743  C  C     . THR A 1 90  ? 7.08060   1.26086  30.50417 1.000 29.79255  ? 88  THR A C     1 
ATOM   744  O  O     . THR A 1 90  ? 6.88866   0.10021  30.11744 1.000 29.72578  ? 88  THR A O     1 
ATOM   745  C  CB    . THR A 1 90  ? 5.88079   3.24483  29.48718 1.000 28.24837  ? 88  THR A CB    1 
ATOM   746  O  OG1   . THR A 1 90  ? 4.53141   3.71187  29.35637 1.000 28.82598  ? 88  THR A OG1   1 
ATOM   747  C  CG2   . THR A 1 90  ? 6.33986   2.60609  28.17099 1.000 27.10738  ? 88  THR A CG2   1 
ATOM   748  N  N     . ALA A 1 91  ? 8.28815   1.69991  30.87071 1.000 29.60715  ? 89  ALA A N     1 
ATOM   749  C  CA    . ALA A 1 91  ? 9.43728   0.80050  30.86038 1.000 28.27987  ? 89  ALA A CA    1 
ATOM   750  C  C     . ALA A 1 91  ? 9.23601   -0.37329 31.81516 1.000 30.84914  ? 89  ALA A C     1 
ATOM   751  O  O     . ALA A 1 91  ? 9.52392   -1.52607 31.46484 1.000 29.18897  ? 89  ALA A O     1 
ATOM   752  C  CB    . ALA A 1 91  ? 10.70642  1.58068  31.20641 1.000 28.67227  ? 89  ALA A CB    1 
ATOM   753  N  N     . GLU A 1 92  ? 8.71829   -0.10776 33.02086 1.000 28.89901  ? 90  GLU A N     1 
ATOM   754  C  CA    . GLU A 1 92  ? 8.50317   -1.18885 33.98000 1.000 30.14578  ? 90  GLU A CA    1 
ATOM   755  C  C     . GLU A 1 92  ? 7.46997   -2.19009 33.46937 1.000 35.36628  ? 90  GLU A C     1 
ATOM   756  O  O     . GLU A 1 92  ? 7.63517   -3.40720 33.62389 1.000 35.42178  ? 90  GLU A O     1 
ATOM   757  C  CB    . GLU A 1 92  ? 8.07458   -0.60990 35.33139 1.000 30.94290  ? 90  GLU A CB    1 
ATOM   758  C  CG    . GLU A 1 92  ? 9.19058   0.14363  36.03716 1.000 32.59645  ? 90  GLU A CG    1 
ATOM   759  C  CD    . GLU A 1 92  ? 8.69825   0.93691  37.22510 1.000 36.62932  ? 90  GLU A CD    1 
ATOM   760  O  OE1   . GLU A 1 92  ? 7.49143   0.84508  37.53551 1.000 40.48901  ? 90  GLU A OE1   1 
ATOM   761  O  OE2   . GLU A 1 92  ? 9.51694   1.64082  37.85617 1.000 33.81161  ? 90  GLU A OE2   1 
ATOM   762  N  N     . VAL A 1 93  ? 6.39239   -1.69858 32.86356 1.000 31.68077  ? 91  VAL A N     1 
ATOM   763  C  CA    . VAL A 1 93  ? 5.39466   -2.59857 32.29674 1.000 32.92467  ? 91  VAL A CA    1 
ATOM   764  C  C     . VAL A 1 93  ? 6.01113   -3.45006 31.19062 1.000 35.63459  ? 91  VAL A C     1 
ATOM   765  O  O     . VAL A 1 93  ? 5.83799   -4.67424 31.15487 1.000 40.29423  ? 91  VAL A O     1 
ATOM   766  C  CB    . VAL A 1 93  ? 4.18542   -1.79317 31.79250 1.000 37.04804  ? 91  VAL A CB    1 
ATOM   767  C  CG1   . VAL A 1 93  ? 3.32285   -2.63952 30.86756 1.000 39.18741  ? 91  VAL A CG1   1 
ATOM   768  C  CG2   . VAL A 1 93  ? 3.38299   -1.27730 32.98213 1.000 35.75981  ? 91  VAL A CG2   1 
ATOM   769  N  N     . CYS A 1 94  ? 6.74620   -2.81743 30.27493 1.000 32.58303  ? 92  CYS A N     1 
ATOM   770  C  CA    . CYS A 1 94  ? 7.30497   -3.55800 29.14677 1.000 33.50162  ? 92  CYS A CA    1 
ATOM   771  C  C     . CYS A 1 94  ? 8.39609   -4.52078 29.60033 1.000 37.15486  ? 92  CYS A C     1 
ATOM   772  O  O     . CYS A 1 94  ? 8.53739   -5.61705 29.04208 1.000 39.11787  ? 92  CYS A O     1 
ATOM   773  C  CB    . CYS A 1 94  ? 7.84176   -2.58166 28.09866 1.000 32.94250  ? 92  CYS A CB    1 
ATOM   774  S  SG    . CYS A 1 94  ? 6.54472   -1.69317 27.22614 1.000 34.24513  ? 92  CYS A SG    1 
ATOM   775  N  N     . SER A 1 95  ? 9.17569   -4.13006 30.61103 1.000 36.35296  ? 93  SER A N     1 
ATOM   776  C  CA    . SER A 1 95  ? 10.20001  -5.02482 31.14822 1.000 35.17495  ? 93  SER A CA    1 
ATOM   777  C  C     . SER A 1 95  ? 9.58334   -6.26853 31.77500 1.000 34.61539  ? 93  SER A C     1 
ATOM   778  O  O     . SER A 1 95  ? 10.08696  -7.38269 31.59265 1.000 38.96999  ? 93  SER A O     1 
ATOM   779  C  CB    . SER A 1 95  ? 11.06005  -4.27615 32.16371 1.000 31.27662  ? 93  SER A CB    1 
ATOM   780  O  OG    . SER A 1 95  ? 12.07771  -5.11521 32.68219 1.000 41.35944  ? 93  SER A OG    1 
ATOM   781  N  N     . ALA A 1 96  ? 8.48883   -6.10443 32.51740 1.000 38.22770  ? 94  ALA A N     1 
ATOM   782  C  CA    . ALA A 1 96  ? 7.90619   -7.23883 33.22538 1.000 41.27753  ? 94  ALA A CA    1 
ATOM   783  C  C     . ALA A 1 96  ? 6.98831   -8.07183 32.33951 1.000 41.17414  ? 94  ALA A C     1 
ATOM   784  O  O     . ALA A 1 96  ? 6.81874   -9.27098 32.58553 1.000 48.58624  ? 94  ALA A O     1 
ATOM   785  C  CB    . ALA A 1 96  ? 7.13249   -6.75169 34.45412 1.000 40.69409  ? 94  ALA A CB    1 
ATOM   786  N  N     . GLU A 1 97  ? 6.39535   -7.46687 31.31585 1.000 42.66497  ? 95  GLU A N     1 
ATOM   787  C  CA    . GLU A 1 97  ? 5.32887   -8.10033 30.55922 1.000 47.04071  ? 95  GLU A CA    1 
ATOM   788  C  C     . GLU A 1 97  ? 5.65550   -8.34057 29.09614 1.000 44.11743  ? 95  GLU A C     1 
ATOM   789  O  O     . GLU A 1 97  ? 5.03280   -9.21305 28.48370 1.000 51.59758  ? 95  GLU A O     1 
ATOM   790  C  CB    . GLU A 1 97  ? 4.05793   -7.24206 30.63138 1.000 47.61931  ? 95  GLU A CB    1 
ATOM   791  C  CG    . GLU A 1 97  ? 3.24041   -7.45777 31.89042 1.000 54.74666  ? 95  GLU A CG    1 
ATOM   792  C  CD    . GLU A 1 97  ? 2.14994   -6.41646 32.05161 1.000 62.71166  ? 95  GLU A CD    1 
ATOM   793  O  OE1   . GLU A 1 97  ? 2.15978   -5.71361 33.08582 1.000 67.11392  ? 95  GLU A OE1   1 
ATOM   794  O  OE2   . GLU A 1 97  ? 1.29788   -6.28823 31.14418 1.000 63.44933  ? 95  GLU A OE2   1 
ATOM   795  N  N     A ARG A 1 98  ? 6.61857   -7.61176 28.52999 0.550 44.27811  ? 96  ARG A N     1 
ATOM   796  N  N     B ARG A 1 98  ? 6.58596   -7.59465 28.50786 0.450 44.27780  ? 96  ARG A N     1 
ATOM   797  C  CA    A ARG A 1 98  ? 6.89296   -7.62934 27.09818 0.550 44.42864  ? 96  ARG A CA    1 
ATOM   798  C  CA    B ARG A 1 98  ? 6.87385   -7.71801 27.08186 0.450 44.41229  ? 96  ARG A CA    1 
ATOM   799  C  C     A ARG A 1 98  ? 8.32818   -8.04145 26.78943 0.550 43.49555  ? 96  ARG A C     1 
ATOM   800  C  C     B ARG A 1 98  ? 8.36152   -7.93325 26.84554 0.450 43.50896  ? 96  ARG A C     1 
ATOM   801  O  O     A ARG A 1 98  ? 8.82649   -7.76289 25.69479 0.550 44.78606  ? 96  ARG A O     1 
ATOM   802  O  O     B ARG A 1 98  ? 8.93681   -7.42771 25.87708 0.450 44.39800  ? 96  ARG A O     1 
ATOM   803  C  CB    A ARG A 1 98  ? 6.60493   -6.25420 26.49570 0.550 42.92794  ? 96  ARG A CB    1 
ATOM   804  C  CB    B ARG A 1 98  ? 6.37032   -6.49754 26.31216 0.450 42.80345  ? 96  ARG A CB    1 
ATOM   805  C  CG    A ARG A 1 98  ? 5.13604   -5.92795 26.30094 0.550 41.77905  ? 96  ARG A CG    1 
ATOM   806  C  CG    B ARG A 1 98  ? 6.08276   -6.76582 24.83701 0.450 44.08151  ? 96  ARG A CG    1 
ATOM   807  C  CD    A ARG A 1 98  ? 5.00328   -4.87023 25.21976 0.550 41.14374  ? 96  ARG A CD    1 
ATOM   808  C  CD    B ARG A 1 98  ? 5.51240   -5.53844 24.12959 0.450 43.43934  ? 96  ARG A CD    1 
ATOM   809  N  NE    A ARG A 1 98  ? 5.92958   -5.14653 24.12796 0.550 43.57829  ? 96  ARG A NE    1 
ATOM   810  N  NE    B ARG A 1 98  ? 4.11710   -5.72429 23.74288 0.450 43.08905  ? 96  ARG A NE    1 
ATOM   811  C  CZ    A ARG A 1 98  ? 5.64175   -5.88756 23.06633 0.550 41.09191  ? 96  ARG A CZ    1 
ATOM   812  C  CZ    B ARG A 1 98  ? 3.08326   -5.21364 24.39877 0.450 44.76371  ? 96  ARG A CZ    1 
ATOM   813  N  NH1   A ARG A 1 98  ? 4.43241   -6.38769 22.88041 0.550 40.18973  ? 96  ARG A NH1   1 
ATOM   814  N  NH1   B ARG A 1 98  ? 3.25036   -4.44968 25.46629 0.450 41.30781  ? 96  ARG A NH1   1 
ATOM   815  N  NH2   A ARG A 1 98  ? 6.59337   -6.13675 22.17232 0.550 43.37886  ? 96  ARG A NH2   1 
ATOM   816  N  NH2   B ARG A 1 98  ? 1.85112   -5.47555 23.97287 0.450 43.11628  ? 96  ARG A NH2   1 
ATOM   817  N  N     . GLY A 1 99  ? 9.00693   -8.68523 27.73484 1.000 45.25337  ? 97  GLY A N     1 
ATOM   818  C  CA    . GLY A 1 99  ? 10.39497  -9.06106 27.53612 1.000 45.48609  ? 97  GLY A CA    1 
ATOM   819  C  C     . GLY A 1 99  ? 11.35883  -7.91485 27.33479 1.000 45.27068  ? 97  GLY A C     1 
ATOM   820  O  O     . GLY A 1 99  ? 12.41925  -8.10977 26.73443 1.000 47.44846  ? 97  GLY A O     1 
ATOM   821  N  N     . GLY A 1 100 ? 11.02867  -6.72266 27.81833 1.000 39.54235  ? 98  GLY A N     1 
ATOM   822  C  CA    . GLY A 1 100 ? 11.91095  -5.58164 27.69559 1.000 39.91024  ? 98  GLY A CA    1 
ATOM   823  C  C     . GLY A 1 100 ? 11.80580  -4.79644 26.40748 1.000 37.35602  ? 98  GLY A C     1 
ATOM   824  O  O     . GLY A 1 100 ? 12.68332  -3.96816 26.13725 1.000 35.90405  ? 98  GLY A O     1 
ATOM   825  N  N     . THR A 1 101 ? 10.75214  -4.99837 25.61791 1.000 39.30286  ? 99  THR A N     1 
ATOM   826  C  CA    . THR A 1 101 ? 10.58167  -4.30611 24.34891 1.000 39.15005  ? 99  THR A CA    1 
ATOM   827  C  C     . THR A 1 101 ? 9.25617   -3.55623 24.32489 1.000 37.72142  ? 99  THR A C     1 
ATOM   828  O  O     . THR A 1 101 ? 8.29307   -3.92710 25.00626 1.000 37.55576  ? 99  THR A O     1 
ATOM   829  C  CB    . THR A 1 101 ? 10.63098  -5.28096 23.15339 1.000 45.11667  ? 99  THR A CB    1 
ATOM   830  O  OG1   . THR A 1 101 ? 9.48320   -6.14041 23.19263 1.000 44.90425  ? 99  THR A OG1   1 
ATOM   831  C  CG2   . THR A 1 101 ? 11.90777  -6.12727 23.18907 1.000 41.68495  ? 99  THR A CG2   1 
ATOM   832  N  N     . LEU A 1 102 ? 9.22212   -2.49632 23.53453 1.000 36.96342  ? 100 LEU A N     1 
ATOM   833  C  CA    . LEU A 1 102 ? 7.98435   -1.78200 23.28570 1.000 36.37740  ? 100 LEU A CA    1 
ATOM   834  C  C     . LEU A 1 102 ? 7.14335   -2.52876 22.25849 1.000 37.18346  ? 100 LEU A C     1 
ATOM   835  O  O     . LEU A 1 102 ? 7.67608   -3.27598 21.43349 1.000 37.05743  ? 100 LEU A O     1 
ATOM   836  C  CB    . LEU A 1 102 ? 8.26234   -0.37311 22.77957 1.000 35.17111  ? 100 LEU A CB    1 
ATOM   837  C  CG    . LEU A 1 102 ? 8.73381   0.59536  23.85987 1.000 32.57205  ? 100 LEU A CG    1 
ATOM   838  C  CD1   . LEU A 1 102 ? 9.42674   1.78781  23.24060 1.000 33.29465  ? 100 LEU A CD1   1 
ATOM   839  C  CD2   . LEU A 1 102 ? 7.56465   1.03892  24.71256 1.000 31.49404  ? 100 LEU A CD2   1 
ATOM   840  N  N     . PRO A 1 103 ? 5.82905   -2.35016 22.29840 1.000 34.62328  ? 101 PRO A N     1 
ATOM   841  C  CA    . PRO A 1 103 ? 4.96916   -2.92730 21.25630 1.000 37.79895  ? 101 PRO A CA    1 
ATOM   842  C  C     . PRO A 1 103 ? 5.18545   -2.21739 19.92794 1.000 36.83013  ? 101 PRO A C     1 
ATOM   843  O  O     . PRO A 1 103 ? 5.83786   -1.17540 19.84410 1.000 34.67261  ? 101 PRO A O     1 
ATOM   844  C  CB    . PRO A 1 103 ? 3.54553   -2.71786 21.77774 1.000 38.63457  ? 101 PRO A CB    1 
ATOM   845  C  CG    . PRO A 1 103 ? 3.65189   -1.79084 22.95293 1.000 37.86943  ? 101 PRO A CG    1 
ATOM   846  C  CD    . PRO A 1 103 ? 5.08959   -1.58876 23.32171 1.000 34.91756  ? 101 PRO A CD    1 
ATOM   847  N  N     . ALA A 1 104 ? 4.61787   -2.80362 18.86696 1.000 41.78178  ? 102 ALA A N     1 
ATOM   848  C  CA    . ALA A 1 104 ? 4.75286   -2.25011 17.52068 1.000 38.95926  ? 102 ALA A CA    1 
ATOM   849  C  C     . ALA A 1 104 ? 3.40460   -2.12789 16.82034 1.000 39.89817  ? 102 ALA A C     1 
ATOM   850  O  O     . ALA A 1 104 ? 3.32117   -2.25703 15.59251 1.000 40.49247  ? 102 ALA A O     1 
ATOM   851  C  CB    . ALA A 1 104 ? 5.71855   -3.08022 16.67319 1.000 37.84173  ? 102 ALA A CB    1 
ATOM   852  N  N     . THR A 1 105 ? 2.33827   -1.88895 17.57693 1.000 40.14299  ? 103 THR A N     1 
ATOM   853  C  CA    . THR A 1 105 ? 1.08325   -1.41077 17.01463 1.000 40.64020  ? 103 THR A CA    1 
ATOM   854  C  C     . THR A 1 105 ? 0.68303   -0.12946 17.73085 1.000 39.87987  ? 103 THR A C     1 
ATOM   855  O  O     . THR A 1 105 ? 1.02343   0.08868  18.90248 1.000 35.62955  ? 103 THR A O     1 
ATOM   856  C  CB    . THR A 1 105 ? -0.06034  -2.43757 17.12072 1.000 43.35245  ? 103 THR A CB    1 
ATOM   857  O  OG1   . THR A 1 105 ? -0.43579  -2.61381 18.49454 1.000 42.86362  ? 103 THR A OG1   1 
ATOM   858  C  CG2   . THR A 1 105 ? 0.34916   -3.77178 16.52722 1.000 40.98710  ? 103 THR A CG2   1 
ATOM   859  N  N     . ASN A 1 106 ? -0.03333  0.72561  17.00586 1.000 33.97665  ? 104 ASN A N     1 
ATOM   860  C  CA    . ASN A 1 106 ? -0.44617  2.00388  17.56963 1.000 36.00557  ? 104 ASN A CA    1 
ATOM   861  C  C     . ASN A 1 106 ? -1.31285  1.79550  18.80574 1.000 36.76258  ? 104 ASN A C     1 
ATOM   862  O  O     . ASN A 1 106 ? -1.10203  2.43587  19.84546 1.000 33.94509  ? 104 ASN A O     1 
ATOM   863  C  CB    . ASN A 1 106 ? -1.18185  2.81390  16.49709 1.000 34.85176  ? 104 ASN A CB    1 
ATOM   864  C  CG    . ASN A 1 106 ? -1.55828  4.19992  16.96408 1.000 33.62561  ? 104 ASN A CG    1 
ATOM   865  O  OD1   . ASN A 1 106 ? -2.38617  4.35216  17.86624 1.000 35.35736  ? 104 ASN A OD1   1 
ATOM   866  N  ND2   . ASN A 1 106 ? -0.98224  5.22033  16.33648 1.000 31.52936  ? 104 ASN A ND2   1 
ATOM   867  N  N     . GLU A 1 107 ? -2.27765  0.87396  18.71350 1.000 35.67956  ? 105 GLU A N     1 
ATOM   868  C  CA    . GLU A 1 107 ? -3.21108  0.64688  19.81140 1.000 36.48014  ? 105 GLU A CA    1 
ATOM   869  C  C     . GLU A 1 107 ? -2.48286  0.19609  21.07217 1.000 40.60784  ? 105 GLU A C     1 
ATOM   870  O  O     . GLU A 1 107 ? -2.77730  0.67849  22.17051 1.000 33.91424  ? 105 GLU A O     1 
ATOM   871  C  CB    . GLU A 1 107 ? -4.26061  -0.38628 19.39635 1.000 39.67063  ? 105 GLU A CB    1 
ATOM   872  N  N     . GLU A 1 108 ? -1.53373  -0.73502 20.93377 1.000 39.81931  ? 106 GLU A N     1 
ATOM   873  C  CA    . GLU A 1 108 ? -0.80265  -1.24031 22.09583 1.000 40.21930  ? 106 GLU A CA    1 
ATOM   874  C  C     . GLU A 1 108 ? 0.07662   -0.16135 22.71010 1.000 37.54906  ? 106 GLU A C     1 
ATOM   875  O  O     . GLU A 1 108 ? 0.26371   -0.12386 23.93408 1.000 35.50206  ? 106 GLU A O     1 
ATOM   876  C  CB    . GLU A 1 108 ? 0.05098   -2.44399 21.69884 1.000 42.43332  ? 106 GLU A CB    1 
ATOM   877  C  CG    . GLU A 1 108 ? -0.72113  -3.71528 21.42915 1.000 42.52296  ? 106 GLU A CG    1 
ATOM   878  C  CD    . GLU A 1 108 ? 0.16943   -4.80774 20.87672 1.000 50.44774  ? 106 GLU A CD    1 
ATOM   879  O  OE1   . GLU A 1 108 ? 0.60741   -4.68065 19.71215 1.000 50.50819  ? 106 GLU A OE1   1 
ATOM   880  O  OE2   . GLU A 1 108 ? 0.44205   -5.78377 21.60613 1.000 51.86672  ? 106 GLU A OE2   1 
ATOM   881  N  N     . LEU A 1 109 ? 0.65145   0.70930  21.87647 1.000 31.96799  ? 107 LEU A N     1 
ATOM   882  C  CA    . LEU A 1 109 ? 1.41264   1.82516  22.41903 1.000 32.22748  ? 107 LEU A CA    1 
ATOM   883  C  C     . LEU A 1 109 ? 0.51276   2.79586  23.17936 1.000 32.73445  ? 107 LEU A C     1 
ATOM   884  O  O     . LEU A 1 109 ? 0.90395   3.31319  24.22879 1.000 30.43390  ? 107 LEU A O     1 
ATOM   885  C  CB    . LEU A 1 109 ? 2.16310   2.54057  21.30036 1.000 28.46536  ? 107 LEU A CB    1 
ATOM   886  C  CG    . LEU A 1 109 ? 3.34695   1.76293  20.72306 1.000 28.58618  ? 107 LEU A CG    1 
ATOM   887  C  CD1   . LEU A 1 109 ? 3.70491   2.32514  19.35278 1.000 28.70619  ? 107 LEU A CD1   1 
ATOM   888  C  CD2   . LEU A 1 109 ? 4.55417   1.82576  21.66668 1.000 30.63952  ? 107 LEU A CD2   1 
ATOM   889  N  N     . GLN A 1 110 ? -0.69420  3.05963  22.67348 1.000 28.28175  ? 108 GLN A N     1 
ATOM   890  C  CA    . GLN A 1 110 ? -1.58107  4.00119  23.35894 1.000 29.14508  ? 108 GLN A CA    1 
ATOM   891  C  C     . GLN A 1 110 ? -2.05461  3.47839  24.70910 1.000 33.20619  ? 108 GLN A C     1 
ATOM   892  O  O     . GLN A 1 110 ? -2.49122  4.26993  25.55213 1.000 32.75219  ? 108 GLN A O     1 
ATOM   893  C  CB    . GLN A 1 110 ? -2.78798  4.33289  22.47513 1.000 30.42295  ? 108 GLN A CB    1 
ATOM   894  C  CG    . GLN A 1 110 ? -2.45911  5.30125  21.33358 1.000 31.16490  ? 108 GLN A CG    1 
ATOM   895  C  CD    . GLN A 1 110 ? -3.66520  6.09931  20.87225 1.000 34.79949  ? 108 GLN A CD    1 
ATOM   896  O  OE1   . GLN A 1 110 ? -4.37138  6.70099  21.68857 1.000 33.97982  ? 108 GLN A OE1   1 
ATOM   897  N  NE2   . GLN A 1 110 ? -3.91249  6.10676  19.55873 1.000 34.90810  ? 108 GLN A NE2   1 
ATOM   898  N  N     . ALA A 1 111 ? -1.97630  2.16768  24.93219 1.000 31.20973  ? 109 ALA A N     1 
ATOM   899  C  CA    . ALA A 1 111 ? -2.31279  1.58996  26.22317 1.000 35.60128  ? 109 ALA A CA    1 
ATOM   900  C  C     . ALA A 1 111 ? -1.26022  1.87298  27.28682 1.000 31.12796  ? 109 ALA A C     1 
ATOM   901  O  O     . ALA A 1 111 ? -1.52341  1.64028  28.47288 1.000 35.90888  ? 109 ALA A O     1 
ATOM   902  C  CB    . ALA A 1 111 ? -2.50886  0.08335  26.07520 1.000 43.28304  ? 109 ALA A CB    1 
ATOM   903  N  N     . LEU A 1 112 ? -0.12056  2.36878  26.90922 1.000 30.55026  ? 110 LEU A N     1 
ATOM   904  C  CA    . LEU A 1 112 ? 0.93616   2.53669  27.89403 1.000 30.31759  ? 110 LEU A CA    1 
ATOM   905  C  C     . LEU A 1 112 ? 0.93460   3.94805  28.48113 1.000 27.48206  ? 110 LEU A C     1 
ATOM   906  O  O     . LEU A 1 112 ? 0.60445   4.91897  27.79122 1.000 28.37319  ? 110 LEU A O     1 
ATOM   907  C  CB    . LEU A 1 112 ? 2.28827   2.23714  27.25602 1.000 29.51503  ? 110 LEU A CB    1 
ATOM   908  C  CG    . LEU A 1 112 ? 2.49042   0.74993  26.94712 1.000 29.23571  ? 110 LEU A CG    1 
ATOM   909  C  CD1   . LEU A 1 112 ? 3.57225   0.55813  25.88474 1.000 31.31340  ? 110 LEU A CD1   1 
ATOM   910  C  CD2   . LEU A 1 112 ? 2.82733   -0.00987 28.23665 1.000 33.33752  ? 110 LEU A CD2   1 
ATOM   911  N  N     . PRO A 1 113 ? 1.30318   4.09670  29.75273 1.000 28.51692  ? 111 PRO A N     1 
ATOM   912  C  CA    . PRO A 1 113 ? 1.25753   5.42559  30.37936 1.000 26.36601  ? 111 PRO A CA    1 
ATOM   913  C  C     . PRO A 1 113 ? 2.15145   6.43983  29.68212 1.000 24.43716  ? 111 PRO A C     1 
ATOM   914  O  O     . PRO A 1 113 ? 3.30748   6.16351  29.33173 1.000 25.74322  ? 111 PRO A O     1 
ATOM   915  C  CB    . PRO A 1 113 ? 1.71686   5.17051  31.82640 1.000 30.24856  ? 111 PRO A CB    1 
ATOM   916  C  CG    . PRO A 1 113 ? 1.95575   3.72449  31.96354 1.000 33.18774  ? 111 PRO A CG    1 
ATOM   917  C  CD    . PRO A 1 113 ? 1.50645   3.00983  30.72606 1.000 28.66633  ? 111 PRO A CD    1 
ATOM   918  N  N     . GLY A 1 114 ? 1.59792   7.64184  29.48998 1.000 24.85743  ? 112 GLY A N     1 
ATOM   919  C  CA    . GLY A 1 114 ? 2.31911   8.72629  28.87085 1.000 23.98705  ? 112 GLY A CA    1 
ATOM   920  C  C     . GLY A 1 114 ? 2.26242   8.73460  27.35831 1.000 24.24216  ? 112 GLY A C     1 
ATOM   921  O  O     . GLY A 1 114 ? 2.73385   9.69710  26.74258 1.000 24.81751  ? 112 GLY A O     1 
ATOM   922  N  N     . ILE A 1 115 ? 1.72909   7.68660  26.74529 1.000 25.98040  ? 113 ILE A N     1 
ATOM   923  C  CA    . ILE A 1 115 ? 1.68645   7.56183  25.28827 1.000 24.57564  ? 113 ILE A CA    1 
ATOM   924  C  C     . ILE A 1 115 ? 0.24380   7.79289  24.86244 1.000 22.54178  ? 113 ILE A C     1 
ATOM   925  O  O     . ILE A 1 115 ? -0.60175  6.90777  25.01395 1.000 26.37046  ? 113 ILE A O     1 
ATOM   926  C  CB    . ILE A 1 115 ? 2.18035   6.19830  24.79762 1.000 23.69154  ? 113 ILE A CB    1 
ATOM   927  C  CG1   . ILE A 1 115 ? 3.59618   5.91991  25.28971 1.000 24.89289  ? 113 ILE A CG1   1 
ATOM   928  C  CG2   . ILE A 1 115 ? 2.09576   6.13622  23.24967 1.000 23.84750  ? 113 ILE A CG2   1 
ATOM   929  C  CD1   . ILE A 1 115 ? 4.16611   4.61564  24.76395 1.000 29.32759  ? 113 ILE A CD1   1 
ATOM   930  N  N     . GLY A 1 116 ? -0.02839  8.97444  24.31265 1.000 23.55676  ? 114 GLY A N     1 
ATOM   931  C  CA    . GLY A 1 116 ? -1.30480  9.26285  23.70905 1.000 24.01580  ? 114 GLY A CA    1 
ATOM   932  C  C     . GLY A 1 116 ? -1.23867  9.06671  22.20966 1.000 23.69603  ? 114 GLY A C     1 
ATOM   933  O  O     . GLY A 1 116 ? -0.28876  8.49220  21.67742 1.000 25.65308  ? 114 GLY A O     1 
ATOM   934  N  N     . PRO A 1 117 ? -2.25485  9.55588  21.49861 1.000 25.65891  ? 115 PRO A N     1 
ATOM   935  C  CA    . PRO A 1 117 ? -2.30557  9.32802  20.03992 1.000 26.08829  ? 115 PRO A CA    1 
ATOM   936  C  C     . PRO A 1 117 ? -1.09126  9.84690  19.30140 1.000 26.49336  ? 115 PRO A C     1 
ATOM   937  O  O     . PRO A 1 117 ? -0.62489  9.20531  18.34313 1.000 27.86537  ? 115 PRO A O     1 
ATOM   938  C  CB    . PRO A 1 117 ? -3.58446  10.07149 19.61854 1.000 27.93928  ? 115 PRO A CB    1 
ATOM   939  C  CG    . PRO A 1 117 ? -4.42170  10.14038 20.88482 1.000 32.31997  ? 115 PRO A CG    1 
ATOM   940  C  CD    . PRO A 1 117 ? -3.43040  10.28531 22.00828 1.000 25.87180  ? 115 PRO A CD    1 
ATOM   941  N  N     . ALA A 1 118 ? -0.57707  11.01512 19.68336 1.000 24.88485  ? 116 ALA A N     1 
ATOM   942  C  CA    . ALA A 1 118 ? 0.54681   11.58583 18.94636 1.000 26.30571  ? 116 ALA A CA    1 
ATOM   943  C  C     . ALA A 1 118 ? 1.83039   10.80562 19.20573 1.000 23.96692  ? 116 ALA A C     1 
ATOM   944  O  O     . ALA A 1 118 ? 2.56719   10.47329 18.27469 1.000 25.48430  ? 116 ALA A O     1 
ATOM   945  C  CB    . ALA A 1 118 ? 0.72717   13.06234 19.30318 1.000 25.22250  ? 116 ALA A CB    1 
ATOM   946  N  N     . THR A 1 119 ? 2.12103   10.49204 20.47085 1.000 23.64988  ? 117 THR A N     1 
ATOM   947  C  CA    . THR A 1 119 ? 3.34942   9.75166  20.74016 1.000 24.37950  ? 117 THR A CA    1 
ATOM   948  C  C     . THR A 1 119 ? 3.29146   8.35577  20.12810 1.000 23.71483  ? 117 THR A C     1 
ATOM   949  O  O     . THR A 1 119 ? 4.29568   7.86093  19.59638 1.000 24.84839  ? 117 THR A O     1 
ATOM   950  C  CB    . THR A 1 119 ? 3.58729   9.70610  22.24922 1.000 21.80228  ? 117 THR A CB    1 
ATOM   951  O  OG1   . THR A 1 119 ? 3.70335   11.05150 22.72767 1.000 23.82572  ? 117 THR A OG1   1 
ATOM   952  C  CG2   . THR A 1 119 ? 4.86811   8.93935  22.57332 1.000 23.13343  ? 117 THR A CG2   1 
ATOM   953  N  N     . ALA A 1 120 ? 2.11193   7.72765  20.14138 1.000 24.41212  ? 118 ALA A N     1 
ATOM   954  C  CA    . ALA A 1 120 ? 1.96177   6.41324  19.51973 1.000 23.28777  ? 118 ALA A CA    1 
ATOM   955  C  C     . ALA A 1 120 ? 2.22128   6.49396  18.02275 1.000 27.06864  ? 118 ALA A C     1 
ATOM   956  O  O     . ALA A 1 120 ? 3.01626   5.72521  17.47501 1.000 27.64075  ? 118 ALA A O     1 
ATOM   957  C  CB    . ALA A 1 120 ? 0.56456   5.84780  19.79516 1.000 26.78215  ? 118 ALA A CB    1 
ATOM   958  N  N     . ALA A 1 121 ? 1.55041   7.42126  17.33890 1.000 25.09020  ? 119 ALA A N     1 
ATOM   959  C  CA    . ALA A 1 121 ? 1.79988   7.58299  15.90762 1.000 25.41491  ? 119 ALA A CA    1 
ATOM   960  C  C     . ALA A 1 121 ? 3.24597   7.98359  15.63151 1.000 26.44394  ? 119 ALA A C     1 
ATOM   961  O  O     . ALA A 1 121 ? 3.82687   7.58142  14.60991 1.000 28.12354  ? 119 ALA A O     1 
ATOM   962  C  CB    . ALA A 1 121 ? 0.82888   8.61539  15.34180 1.000 26.23067  ? 119 ALA A CB    1 
ATOM   963  N  N     . GLY A 1 122 ? 3.85034   8.76087  16.53227 1.000 25.30156  ? 120 GLY A N     1 
ATOM   964  C  CA    . GLY A 1 122 ? 5.23152   9.16474  16.33488 1.000 25.99247  ? 120 GLY A CA    1 
ATOM   965  C  C     . GLY A 1 122 ? 6.19491   7.99801  16.43271 1.000 28.27159  ? 120 GLY A C     1 
ATOM   966  O  O     . GLY A 1 122 ? 7.10768   7.86277  15.61297 1.000 27.48526  ? 120 GLY A O     1 
ATOM   967  N  N     . VAL A 1 123 ? 6.00120   7.12961  17.42640 1.000 25.95496  ? 121 VAL A N     1 
ATOM   968  C  CA    . VAL A 1 123 ? 6.84043   5.94059  17.53442 1.000 25.32058  ? 121 VAL A CA    1 
ATOM   969  C  C     . VAL A 1 123 ? 6.65450   5.05020  16.31008 1.000 26.03093  ? 121 VAL A C     1 
ATOM   970  O  O     . VAL A 1 123 ? 7.63035   4.57539  15.71004 1.000 27.06117  ? 121 VAL A O     1 
ATOM   971  C  CB    . VAL A 1 123 ? 6.53445   5.18295  18.83742 1.000 26.78611  ? 121 VAL A CB    1 
ATOM   972  C  CG1   . VAL A 1 123 ? 7.22164   3.82391  18.82439 1.000 29.10600  ? 121 VAL A CG1   1 
ATOM   973  C  CG2   . VAL A 1 123 ? 6.97515   6.01636  20.04061 1.000 26.58464  ? 121 VAL A CG2   1 
ATOM   974  N  N     . MET A 1 124 ? 5.39967   4.82256  15.90227 1.000 25.90005  ? 122 MET A N     1 
ATOM   975  C  CA    . MET A 1 124 ? 5.17151   3.99260  14.72076 1.000 29.51540  ? 122 MET A CA    1 
ATOM   976  C  C     . MET A 1 124 ? 5.80343   4.59394  13.46899 1.000 29.27437  ? 122 MET A C     1 
ATOM   977  O  O     . MET A 1 124 ? 6.41717   3.87209  12.67266 1.000 29.98362  ? 122 MET A O     1 
ATOM   978  C  CB    . MET A 1 124 ? 3.67871   3.73637  14.49525 1.000 29.23403  ? 122 MET A CB    1 
ATOM   979  C  CG    . MET A 1 124 ? 2.96360   2.99708  15.62526 1.000 31.46816  ? 122 MET A CG    1 
ATOM   980  S  SD    . MET A 1 124 ? 3.60180   1.31125  15.77786 1.000 35.60589  ? 122 MET A SD    1 
ATOM   981  C  CE    . MET A 1 124 ? 2.82684   0.52956  14.35838 1.000 44.98899  ? 122 MET A CE    1 
ATOM   982  N  N     . ALA A 1 125 ? 5.66610   5.90672  13.27059 1.000 26.44341  ? 123 ALA A N     1 
ATOM   983  C  CA    . ALA A 1 125 ? 6.23043   6.52157  12.07221 1.000 28.49545  ? 123 ALA A CA    1 
ATOM   984  C  C     . ALA A 1 125 ? 7.75023   6.60542  12.15668 1.000 29.34415  ? 123 ALA A C     1 
ATOM   985  O  O     . ALA A 1 125 ? 8.45738   6.28967  11.18665 1.000 28.54326  ? 123 ALA A O     1 
ATOM   986  C  CB    . ALA A 1 125 ? 5.63950   7.91329  11.86444 1.000 29.29252  ? 123 ALA A CB    1 
ATOM   987  N  N     . PHE A 1 126 ? 8.27575   7.05024  13.30373 1.000 27.28907  ? 124 PHE A N     1 
ATOM   988  C  CA    . PHE A 1 126 ? 9.69927   7.37973  13.35752 1.000 28.53842  ? 124 PHE A CA    1 
ATOM   989  C  C     . PHE A 1 126 ? 10.56951  6.15387  13.61993 1.000 30.41813  ? 124 PHE A C     1 
ATOM   990  O  O     . PHE A 1 126 ? 11.65313  6.03063  13.03922 1.000 35.04196  ? 124 PHE A O     1 
ATOM   991  C  CB    . PHE A 1 126 ? 9.94852   8.45888  14.41422 1.000 26.15909  ? 124 PHE A CB    1 
ATOM   992  C  CG    . PHE A 1 126 ? 9.21210   9.74671  14.14644 1.000 28.88902  ? 124 PHE A CG    1 
ATOM   993  C  CD1   . PHE A 1 126 ? 9.15117   10.27087 12.86450 1.000 32.19656  ? 124 PHE A CD1   1 
ATOM   994  C  CD2   . PHE A 1 126 ? 8.56910   10.42334 15.17353 1.000 26.52688  ? 124 PHE A CD2   1 
ATOM   995  C  CE1   . PHE A 1 126 ? 8.46322   11.44951 12.60375 1.000 26.15007  ? 124 PHE A CE1   1 
ATOM   996  C  CE2   . PHE A 1 126 ? 7.86578   11.61166 14.91612 1.000 27.94694  ? 124 PHE A CE2   1 
ATOM   997  C  CZ    . PHE A 1 126 ? 7.82710   12.11951 13.61377 1.000 29.67062  ? 124 PHE A CZ    1 
ATOM   998  N  N     . ALA A 1 127 ? 10.11811  5.23436  14.47397 1.000 31.17081  ? 125 ALA A N     1 
ATOM   999  C  CA    . ALA A 1 127 ? 10.87382  4.02384  14.76754 1.000 34.56290  ? 125 ALA A CA    1 
ATOM   1000 C  C     . ALA A 1 127 ? 10.61271  2.92481  13.74677 1.000 35.42814  ? 125 ALA A C     1 
ATOM   1001 O  O     . ALA A 1 127 ? 11.54751  2.22773  13.33602 1.000 35.93326  ? 125 ALA A O     1 
ATOM   1002 C  CB    . ALA A 1 127 ? 10.53740  3.51208  16.17376 1.000 33.42992  ? 125 ALA A CB    1 
ATOM   1003 N  N     . TYR A 1 128 ? 9.36213   2.76771  13.30801 1.000 33.84911  ? 126 TYR A N     1 
ATOM   1004 C  CA    . TYR A 1 128 ? 8.99112   1.66368  12.43494 1.000 33.84982  ? 126 TYR A CA    1 
ATOM   1005 C  C     . TYR A 1 128 ? 8.65743   2.07533  11.00136 1.000 33.80168  ? 126 TYR A C     1 
ATOM   1006 O  O     . TYR A 1 128 ? 8.38678   1.19540  10.18035 1.000 36.89622  ? 126 TYR A O     1 
ATOM   1007 C  CB    . TYR A 1 128 ? 7.80014   0.89780  13.02866 1.000 37.39370  ? 126 TYR A CB    1 
ATOM   1008 C  CG    . TYR A 1 128 ? 7.95582   0.42488  14.47150 1.000 35.57345  ? 126 TYR A CG    1 
ATOM   1009 C  CD1   . TYR A 1 128 ? 8.94205   -0.48340 14.83414 1.000 43.50501  ? 126 TYR A CD1   1 
ATOM   1010 C  CD2   . TYR A 1 128 ? 7.08864   0.87238  15.46304 1.000 35.81912  ? 126 TYR A CD2   1 
ATOM   1011 C  CE1   . TYR A 1 128 ? 9.06259   -0.92559 16.15271 1.000 38.29663  ? 126 TYR A CE1   1 
ATOM   1012 C  CE2   . TYR A 1 128 ? 7.20956   0.43839  16.77746 1.000 37.36006  ? 126 TYR A CE2   1 
ATOM   1013 C  CZ    . TYR A 1 128 ? 8.19236   -0.45797 17.11195 1.000 39.26257  ? 126 TYR A CZ    1 
ATOM   1014 O  OH    . TYR A 1 128 ? 8.29535   -0.88046 18.42938 1.000 42.93828  ? 126 TYR A OH    1 
ATOM   1015 N  N     . ASN A 1 129 ? 8.68027   3.36874  10.66812 1.000 33.68923  ? 127 ASN A N     1 
ATOM   1016 C  CA    . ASN A 1 129 ? 8.27162   3.83903  9.33749  1.000 33.79652  ? 127 ASN A CA    1 
ATOM   1017 C  C     . ASN A 1 129 ? 6.90034   3.30755  8.93912  1.000 34.89254  ? 127 ASN A C     1 
ATOM   1018 O  O     . ASN A 1 129 ? 6.67940   2.89215  7.79956  1.000 37.25366  ? 127 ASN A O     1 
ATOM   1019 C  CB    . ASN A 1 129 ? 9.29666   3.48192  8.26185  1.000 38.76019  ? 127 ASN A CB    1 
ATOM   1020 C  CG    . ASN A 1 129 ? 9.27759   4.45930  7.08760  1.000 38.52175  ? 127 ASN A CG    1 
ATOM   1021 O  OD1   . ASN A 1 129 ? 8.63208   5.50690  7.13483  1.000 37.78965  ? 127 ASN A OD1   1 
ATOM   1022 N  ND2   . ASN A 1 129 ? 9.95185   4.08672  6.00265  1.000 50.16669  ? 127 ASN A ND2   1 
ATOM   1023 N  N     . ARG A 1 130 ? 5.96950   3.32709  9.88480  1.000 32.14172  ? 128 ARG A N     1 
ATOM   1024 C  CA    . ARG A 1 130 ? 4.60891   2.88381  9.63564  1.000 34.66561  ? 128 ARG A CA    1 
ATOM   1025 C  C     . ARG A 1 130 ? 3.64509   4.06795  9.66192  1.000 30.77554  ? 128 ARG A C     1 
ATOM   1026 O  O     . ARG A 1 130 ? 3.82329   4.99891  10.45711 1.000 29.23790  ? 128 ARG A O     1 
ATOM   1027 C  CB    . ARG A 1 130 ? 4.18715   1.83923  10.67440 1.000 38.79480  ? 128 ARG A CB    1 
ATOM   1028 C  CG    . ARG A 1 130 ? 4.91034   0.49961  10.51171 1.000 32.99054  ? 128 ARG A CG    1 
ATOM   1029 C  CD    . ARG A 1 130 ? 4.78152   -0.02808 9.08463  1.000 40.47461  ? 128 ARG A CD    1 
ATOM   1030 N  N     . PRO A 1 131 ? 2.64476   4.07926  8.78645  1.000 32.65891  ? 129 PRO A N     1 
ATOM   1031 C  CA    . PRO A 1 131 ? 1.77770   5.25341  8.65572  1.000 30.64742  ? 129 PRO A CA    1 
ATOM   1032 C  C     . PRO A 1 131 ? 0.76033   5.35688  9.78542  1.000 33.23654  ? 129 PRO A C     1 
ATOM   1033 O  O     . PRO A 1 131 ? 0.47307   4.40108  10.50645 1.000 35.58576  ? 129 PRO A O     1 
ATOM   1034 C  CB    . PRO A 1 131 ? 1.07889   5.01994  7.30965  1.000 32.33703  ? 129 PRO A CB    1 
ATOM   1035 C  CG    . PRO A 1 131 ? 1.02437   3.52914  7.19585  1.000 36.37342  ? 129 PRO A CG    1 
ATOM   1036 C  CD    . PRO A 1 131 ? 2.31673   3.03217  7.80613  1.000 33.16570  ? 129 PRO A CD    1 
ATOM   1037 N  N     . GLY A 1 132 ? 0.20872   6.55240  9.91462  1.000 29.52309  ? 130 GLY A N     1 
ATOM   1038 C  CA    . GLY A 1 132 ? -0.73167  6.84785  10.97764 1.000 33.54750  ? 130 GLY A CA    1 
ATOM   1039 C  C     . GLY A 1 132 ? -1.01521  8.33336  11.00593 1.000 34.90433  ? 130 GLY A C     1 
ATOM   1040 O  O     . GLY A 1 132 ? -0.53476  9.10202  10.16567 1.000 33.77999  ? 130 GLY A O     1 
ATOM   1041 N  N     . VAL A 1 133 ? -1.82599  8.72513  11.97985 1.000 27.51722  ? 131 VAL A N     1 
ATOM   1042 C  CA    . VAL A 1 133 ? -2.24893  10.11186 12.14550 1.000 27.68452  ? 131 VAL A CA    1 
ATOM   1043 C  C     . VAL A 1 133 ? -1.41877  10.70730 13.28401 1.000 28.59859  ? 131 VAL A C     1 
ATOM   1044 O  O     . VAL A 1 133 ? -1.64990  10.42954 14.46878 1.000 28.30743  ? 131 VAL A O     1 
ATOM   1045 C  CB    . VAL A 1 133 ? -3.75420  10.21515 12.41193 1.000 31.17221  ? 131 VAL A CB    1 
ATOM   1046 C  CG1   . VAL A 1 133 ? -4.16631  11.67244 12.56915 1.000 33.10961  ? 131 VAL A CG1   1 
ATOM   1047 C  CG2   . VAL A 1 133 ? -4.54654  9.53899  11.29723 1.000 30.24309  ? 131 VAL A CG2   1 
ATOM   1048 N  N     . TYR A 1 134 ? -0.43976  11.52939 12.92379 1.000 27.53714  ? 132 TYR A N     1 
ATOM   1049 C  CA    . TYR A 1 134 ? 0.45494   12.20033 13.86786 1.000 24.72649  ? 132 TYR A CA    1 
ATOM   1050 C  C     . TYR A 1 134 ? 0.11145   13.68490 13.83445 1.000 26.32915  ? 132 TYR A C     1 
ATOM   1051 O  O     . TYR A 1 134 ? 0.43380   14.38375 12.86583 1.000 27.31335  ? 132 TYR A O     1 
ATOM   1052 C  CB    . TYR A 1 134 ? 1.91244   11.94248 13.48579 1.000 22.91997  ? 132 TYR A CB    1 
ATOM   1053 C  CG    . TYR A 1 134 ? 2.95800   12.59442 14.35913 1.000 25.59394  ? 132 TYR A CG    1 
ATOM   1054 C  CD1   . TYR A 1 134 ? 3.16471   12.17713 15.67448 1.000 24.32939  ? 132 TYR A CD1   1 
ATOM   1055 C  CD2   . TYR A 1 134 ? 3.75793   13.61821 13.86123 1.000 22.41853  ? 132 TYR A CD2   1 
ATOM   1056 C  CE1   . TYR A 1 134 ? 4.13943   12.77195 16.46228 1.000 26.16065  ? 132 TYR A CE1   1 
ATOM   1057 C  CE2   . TYR A 1 134 ? 4.74352   14.20675 14.63231 1.000 24.82631  ? 132 TYR A CE2   1 
ATOM   1058 C  CZ    . TYR A 1 134 ? 4.92173   13.78257 15.93804 1.000 26.45033  ? 132 TYR A CZ    1 
ATOM   1059 O  OH    . TYR A 1 134 ? 5.89854   14.35408 16.72363 1.000 27.14387  ? 132 TYR A OH    1 
ATOM   1060 N  N     . LEU A 1 135 ? -0.59079  14.14931 14.86404 1.000 24.16015  ? 133 LEU A N     1 
ATOM   1061 C  CA    . LEU A 1 135 ? -1.13162  15.50574 14.91389 1.000 22.94133  ? 133 LEU A CA    1 
ATOM   1062 C  C     . LEU A 1 135 ? -0.68176  16.16794 16.21665 1.000 23.49924  ? 133 LEU A C     1 
ATOM   1063 O  O     . LEU A 1 135 ? -1.30948  15.98290 17.26238 1.000 27.27059  ? 133 LEU A O     1 
ATOM   1064 C  CB    . LEU A 1 135 ? -2.64999  15.47573 14.79720 1.000 23.88207  ? 133 LEU A CB    1 
ATOM   1065 C  CG    . LEU A 1 135 ? -3.40991  16.80634 14.83248 1.000 26.49857  ? 133 LEU A CG    1 
ATOM   1066 C  CD1   . LEU A 1 135 ? -2.82083  17.83037 13.84897 1.000 25.19664  ? 133 LEU A CD1   1 
ATOM   1067 C  CD2   . LEU A 1 135 ? -4.89763  16.57571 14.56541 1.000 29.66613  ? 133 LEU A CD2   1 
ATOM   1068 N  N     . GLU A 1 136 ? 0.40830   16.91032 16.15815 1.000 22.81934  ? 134 GLU A N     1 
ATOM   1069 C  CA    . GLU A 1 136 ? 0.89753   17.75531 17.25569 1.000 24.95390  ? 134 GLU A CA    1 
ATOM   1070 C  C     . GLU A 1 136 ? 0.95058   19.19850 16.75118 1.000 22.98848  ? 134 GLU A C     1 
ATOM   1071 O  O     . GLU A 1 136 ? 0.35793   19.52918 15.72006 1.000 24.27100  ? 134 GLU A O     1 
ATOM   1072 C  CB    . GLU A 1 136 ? 2.21839   17.19421 17.82785 1.000 26.15352  ? 134 GLU A CB    1 
ATOM   1073 C  CG    . GLU A 1 136 ? 3.19831   16.89798 16.71462 1.000 24.68358  ? 134 GLU A CG    1 
ATOM   1074 C  CD    . GLU A 1 136 ? 3.64089   18.12078 15.96866 1.000 27.08301  ? 134 GLU A CD    1 
ATOM   1075 O  OE1   . GLU A 1 136 ? 4.34673   19.00799 16.48315 1.000 28.36089  ? 134 GLU A OE1   1 
ATOM   1076 O  OE2   . GLU A 1 136 ? 3.01751   18.30918 14.90197 1.000 29.55565  ? 134 GLU A OE2   1 
ATOM   1077 N  N     . THR A 1 137 ? 1.62705   20.07818 17.48977 1.000 19.86347  ? 135 THR A N     1 
ATOM   1078 C  CA    . THR A 1 137 ? 1.46249   21.50643 17.23615 1.000 23.73400  ? 135 THR A CA    1 
ATOM   1079 C  C     . THR A 1 137 ? 1.99011   21.91533 15.86070 1.000 24.16495  ? 135 THR A C     1 
ATOM   1080 O  O     . THR A 1 137 ? 1.39546   22.77894 15.20016 1.000 21.85144  ? 135 THR A O     1 
ATOM   1081 C  CB    . THR A 1 137 ? 2.12916   22.32081 18.34590 1.000 23.08750  ? 135 THR A CB    1 
ATOM   1082 O  OG1   . THR A 1 137 ? 1.77441   23.70029 18.18009 1.000 23.14293  ? 135 THR A OG1   1 
ATOM   1083 C  CG2   . THR A 1 137 ? 3.67724   22.13799 18.33830 1.000 21.23470  ? 135 THR A CG2   1 
ATOM   1084 N  N     . ASN A 1 138 ? 3.08751   21.29983 15.40615 1.000 21.36747  ? 136 ASN A N     1 
ATOM   1085 C  CA    . ASN A 1 138 ? 3.65321   21.66092 14.10410 1.000 20.99329  ? 136 ASN A CA    1 
ATOM   1086 C  C     . ASN A 1 138 ? 2.80336   21.15203 12.94589 1.000 23.17506  ? 136 ASN A C     1 
ATOM   1087 O  O     . ASN A 1 138 ? 2.56269   21.89018 11.98298 1.000 23.48327  ? 136 ASN A O     1 
ATOM   1088 C  CB    . ASN A 1 138 ? 5.07088   21.13353 14.01326 1.000 22.18980  ? 136 ASN A CB    1 
ATOM   1089 C  CG    . ASN A 1 138 ? 5.96132   21.81224 15.01233 1.000 26.18240  ? 136 ASN A CG    1 
ATOM   1090 O  OD1   . ASN A 1 138 ? 6.17717   23.02118 14.91095 1.000 26.40956  ? 136 ASN A OD1   1 
ATOM   1091 N  ND2   . ASN A 1 138 ? 6.40990   21.07067 16.04123 1.000 24.37819  ? 136 ASN A ND2   1 
ATOM   1092 N  N     . VAL A 1 139 ? 2.37691   19.88598 13.00213 1.000 22.10861  ? 137 VAL A N     1 
ATOM   1093 C  CA    . VAL A 1 139 ? 1.47712   19.35317 11.97660 1.000 23.73159  ? 137 VAL A CA    1 
ATOM   1094 C  C     . VAL A 1 139 ? 0.18237   20.15870 11.93567 1.000 26.65330  ? 137 VAL A C     1 
ATOM   1095 O  O     . VAL A 1 139 ? -0.31360  20.51898 10.85363 1.000 24.68930  ? 137 VAL A O     1 
ATOM   1096 C  CB    . VAL A 1 139 ? 1.19663   17.85699 12.21938 1.000 21.51242  ? 137 VAL A CB    1 
ATOM   1097 C  CG1   . VAL A 1 139 ? 0.09900   17.34894 11.25365 1.000 23.19168  ? 137 VAL A CG1   1 
ATOM   1098 C  CG2   . VAL A 1 139 ? 2.48056   17.02543 12.10511 1.000 23.57065  ? 137 VAL A CG2   1 
ATOM   1099 N  N     . ARG A 1 140 ? -0.39794  20.43430 13.11302 1.000 21.74900  ? 138 ARG A N     1 
ATOM   1100 C  CA    . ARG A 1 140 ? -1.61770  21.23319 13.19298 1.000 21.61871  ? 138 ARG A CA    1 
ATOM   1101 C  C     . ARG A 1 140 ? -1.42830  22.56958 12.48792 1.000 24.89023  ? 138 ARG A C     1 
ATOM   1102 O  O     . ARG A 1 140 ? -2.26476  22.99151 11.68185 1.000 24.05132  ? 138 ARG A O     1 
ATOM   1103 C  CB    . ARG A 1 140 ? -1.99907  21.44317 14.67218 1.000 22.67644  ? 138 ARG A CB    1 
ATOM   1104 C  CG    . ARG A 1 140 ? -3.33139  22.14560 14.81906 1.000 21.56127  ? 138 ARG A CG    1 
ATOM   1105 C  CD    . ARG A 1 140 ? -3.69969  22.34259 16.30587 1.000 27.99378  ? 138 ARG A CD    1 
ATOM   1106 N  NE    . ARG A 1 140 ? -3.94565  21.05962 16.95467 1.000 25.64822  ? 138 ARG A NE    1 
ATOM   1107 C  CZ    . ARG A 1 140 ? -3.13670  20.46562 17.82766 1.000 26.68864  ? 138 ARG A CZ    1 
ATOM   1108 N  NH1   . ARG A 1 140 ? -1.99837  21.02646 18.22842 1.000 24.84980  ? 138 ARG A NH1   1 
ATOM   1109 N  NH2   . ARG A 1 140 ? -3.47503  19.27395 18.31040 1.000 26.44963  ? 138 ARG A NH2   1 
ATOM   1110 N  N     . THR A 1 141 ? -0.28839  23.21836 12.74431 1.000 23.02245  ? 139 THR A N     1 
ATOM   1111 C  CA    . THR A 1 141 ? 0.01066   24.49484 12.10755 1.000 22.46360  ? 139 THR A CA    1 
ATOM   1112 C  C     . THR A 1 141 ? 0.05172   24.36571 10.58484 1.000 24.86791  ? 139 THR A C     1 
ATOM   1113 O  O     . THR A 1 141 ? -0.52614  25.19803 9.88050  1.000 24.45191  ? 139 THR A O     1 
ATOM   1114 C  CB    . THR A 1 141 ? 1.32667   25.05525 12.67134 1.000 26.34406  ? 139 THR A CB    1 
ATOM   1115 O  OG1   . THR A 1 141 ? 1.02712   25.99238 13.72218 1.000 25.70111  ? 139 THR A OG1   1 
ATOM   1116 C  CG2   . THR A 1 141 ? 2.13522   25.77645 11.59433 1.000 24.56390  ? 139 THR A CG2   1 
ATOM   1117 N  N     . VAL A 1 142 ? 0.69235   23.31421 10.05684 1.000 23.54818  ? 140 VAL A N     1 
ATOM   1118 C  CA    . VAL A 1 142 ? 0.78965   23.17190 8.59805  1.000 24.73663  ? 140 VAL A CA    1 
ATOM   1119 C  C     . VAL A 1 142 ? -0.59793  23.02029 7.98995  1.000 23.76270  ? 140 VAL A C     1 
ATOM   1120 O  O     . VAL A 1 142 ? -0.93607  23.68526 7.00483  1.000 25.48893  ? 140 VAL A O     1 
ATOM   1121 C  CB    . VAL A 1 142 ? 1.68697   21.98292 8.21163  1.000 21.76871  ? 140 VAL A CB    1 
ATOM   1122 C  CG1   . VAL A 1 142 ? 1.61982   21.73156 6.67128  1.000 24.35711  ? 140 VAL A CG1   1 
ATOM   1123 C  CG2   . VAL A 1 142 ? 3.15099   22.22332 8.64499  1.000 23.37943  ? 140 VAL A CG2   1 
ATOM   1124 N  N     . PHE A 1 143 ? -1.41707  22.13618 8.56449  1.000 24.24287  ? 141 PHE A N     1 
ATOM   1125 C  CA    . PHE A 1 143 ? -2.73513  21.86174 7.98964  1.000 23.43923  ? 141 PHE A CA    1 
ATOM   1126 C  C     . PHE A 1 143 ? -3.65483  23.06927 8.11009  1.000 26.31949  ? 141 PHE A C     1 
ATOM   1127 O  O     . PHE A 1 143 ? -4.43129  23.36231 7.18862  1.000 26.66114  ? 141 PHE A O     1 
ATOM   1128 C  CB    . PHE A 1 143 ? -3.33211  20.61421 8.65226  1.000 25.10236  ? 141 PHE A CB    1 
ATOM   1129 C  CG    . PHE A 1 143 ? -2.83108  19.31755 8.04819  1.000 24.09869  ? 141 PHE A CG    1 
ATOM   1130 C  CD1   . PHE A 1 143 ? -1.57741  18.81449 8.38354  1.000 24.88287  ? 141 PHE A CD1   1 
ATOM   1131 C  CD2   . PHE A 1 143 ? -3.60211  18.62804 7.11914  1.000 26.07994  ? 141 PHE A CD2   1 
ATOM   1132 C  CE1   . PHE A 1 143 ? -1.12019  17.64403 7.82003  1.000 24.76793  ? 141 PHE A CE1   1 
ATOM   1133 C  CE2   . PHE A 1 143 ? -3.14197  17.45123 6.52241  1.000 25.18414  ? 141 PHE A CE2   1 
ATOM   1134 C  CZ    . PHE A 1 143 ? -1.89787  16.95440 6.87816  1.000 23.58681  ? 141 PHE A CZ    1 
ATOM   1135 N  N     . LEU A 1 144 ? -3.58005  23.79625 9.23035  1.000 26.92452  ? 142 LEU A N     1 
ATOM   1136 C  CA    . LEU A 1 144 ? -4.36850  25.01796 9.36384  1.000 26.42103  ? 142 LEU A CA    1 
ATOM   1137 C  C     . LEU A 1 144 ? -3.94609  26.06601 8.34739  1.000 27.36599  ? 142 LEU A C     1 
ATOM   1138 O  O     . LEU A 1 144 ? -4.79200  26.74841 7.74930  1.000 28.29218  ? 142 LEU A O     1 
ATOM   1139 C  CB    . LEU A 1 144 ? -4.22603  25.57862 10.77570 1.000 25.61889  ? 142 LEU A CB    1 
ATOM   1140 C  CG    . LEU A 1 144 ? -4.95147  24.79957 11.87879 1.000 27.98227  ? 142 LEU A CG    1 
ATOM   1141 C  CD1   . LEU A 1 144 ? -4.58898  25.39955 13.22910 1.000 28.19093  ? 142 LEU A CD1   1 
ATOM   1142 C  CD2   . LEU A 1 144 ? -6.46199  24.75798 11.67375 1.000 29.72571  ? 142 LEU A CD2   1 
ATOM   1143 N  N     . HIS A 1 145 ? -2.63533  26.22836 8.16902  1.000 26.58351  ? 143 HIS A N     1 
ATOM   1144 C  CA    . HIS A 1 145 ? -2.12326  27.23803 7.25752  1.000 27.60965  ? 143 HIS A CA    1 
ATOM   1145 C  C     . HIS A 1 145 ? -2.44959  26.89227 5.81072  1.000 29.08287  ? 143 HIS A C     1 
ATOM   1146 O  O     . HIS A 1 145 ? -2.87525  27.76310 5.04114  1.000 33.28705  ? 143 HIS A O     1 
ATOM   1147 C  CB    . HIS A 1 145 ? -0.61244  27.37483 7.42998  1.000 26.72909  ? 143 HIS A CB    1 
ATOM   1148 C  CG    . HIS A 1 145 ? -0.02602  28.50269 6.64506  1.000 31.44668  ? 143 HIS A CG    1 
ATOM   1149 N  ND1   . HIS A 1 145 ? -0.26604  29.82565 6.95239  1.000 32.72422  ? 143 HIS A ND1   1 
ATOM   1150 C  CD2   . HIS A 1 145 ? 0.74352   28.50753 5.53034  1.000 30.14824  ? 143 HIS A CD2   1 
ATOM   1151 C  CE1   . HIS A 1 145 ? 0.35171   30.59704 6.07446  1.000 35.03721  ? 143 HIS A CE1   1 
ATOM   1152 N  NE2   . HIS A 1 145 ? 0.96560   29.82180 5.19822  1.000 33.88245  ? 143 HIS A NE2   1 
ATOM   1153 N  N     . GLU A 1 146 ? -2.25609  25.62809 5.42282  1.000 28.35663  ? 144 GLU A N     1 
ATOM   1154 C  CA    . GLU A 1 146 ? -2.33576  25.23136 4.01451  1.000 27.24260  ? 144 GLU A CA    1 
ATOM   1155 C  C     . GLU A 1 146 ? -3.76071  24.92568 3.55978  1.000 32.49632  ? 144 GLU A C     1 
ATOM   1156 O  O     . GLU A 1 146 ? -4.14646  25.29744 2.44534  1.000 33.94012  ? 144 GLU A O     1 
ATOM   1157 C  CB    . GLU A 1 146 ? -1.46187  23.99943 3.77876  1.000 29.87441  ? 144 GLU A CB    1 
ATOM   1158 C  CG    . GLU A 1 146 ? 0.03932   24.25379 3.75556  1.000 29.94000  ? 144 GLU A CG    1 
ATOM   1159 C  CD    . GLU A 1 146 ? 0.45317   25.31320 2.74725  1.000 40.15268  ? 144 GLU A CD    1 
ATOM   1160 O  OE1   . GLU A 1 146 ? -0.18810  25.38383 1.66939  1.000 38.45504  ? 144 GLU A OE1   1 
ATOM   1161 O  OE2   . GLU A 1 146 ? 1.43817   26.05063 3.01679  1.000 37.84572  ? 144 GLU A OE2   1 
ATOM   1162 N  N     . LEU A 1 147 ? -4.54881  24.23742 4.38769  1.000 27.81618  ? 145 LEU A N     1 
ATOM   1163 C  CA    . LEU A 1 147 ? -5.85054  23.74029 3.96894  1.000 29.27701  ? 145 LEU A CA    1 
ATOM   1164 C  C     . LEU A 1 147 ? -7.01933  24.47778 4.60331  1.000 32.24271  ? 145 LEU A C     1 
ATOM   1165 O  O     . LEU A 1 147 ? -8.15130  24.32338 4.13631  1.000 33.12329  ? 145 LEU A O     1 
ATOM   1166 C  CB    . LEU A 1 147 ? -5.95698  22.23820 4.27622  1.000 28.13730  ? 145 LEU A CB    1 
ATOM   1167 C  CG    . LEU A 1 147 ? -4.75392  21.44936 3.74519  1.000 29.00996  ? 145 LEU A CG    1 
ATOM   1168 C  CD1   . LEU A 1 147 ? -4.94367  19.98096 4.03987  1.000 31.05142  ? 145 LEU A CD1   1 
ATOM   1169 C  CD2   . LEU A 1 147 ? -4.57458  21.68422 2.22531  1.000 31.70508  ? 145 LEU A CD2   1 
ATOM   1170 N  N     . PHE A 1 148 ? -6.78175  25.27084 5.64429  1.000 30.06909  ? 146 PHE A N     1 
ATOM   1171 C  CA    . PHE A 1 148 ? -7.84264  25.99932 6.32445  1.000 30.93180  ? 146 PHE A CA    1 
ATOM   1172 C  C     . PHE A 1 148 ? -7.49542  27.47540 6.43992  1.000 35.30802  ? 146 PHE A C     1 
ATOM   1173 O  O     . PHE A 1 148 ? -7.78655  28.12714 7.44564  1.000 33.92778  ? 146 PHE A O     1 
ATOM   1174 C  CB    . PHE A 1 148 ? -8.11972  25.37921 7.69121  1.000 29.98405  ? 146 PHE A CB    1 
ATOM   1175 C  CG    . PHE A 1 148 ? -8.64982  23.98055 7.60538  1.000 32.52777  ? 146 PHE A CG    1 
ATOM   1176 C  CD1   . PHE A 1 148 ? -7.79222  22.89592 7.55118  1.000 30.06801  ? 146 PHE A CD1   1 
ATOM   1177 C  CD2   . PHE A 1 148 ? -10.01552 23.75234 7.53578  1.000 37.36737  ? 146 PHE A CD2   1 
ATOM   1178 C  CE1   . PHE A 1 148 ? -8.30324  21.60010 7.44166  1.000 30.05225  ? 146 PHE A CE1   1 
ATOM   1179 C  CE2   . PHE A 1 148 ? -10.51789 22.46734 7.43600  1.000 36.32897  ? 146 PHE A CE2   1 
ATOM   1180 C  CZ    . PHE A 1 148 ? -9.65980  21.39279 7.38424  1.000 32.92599  ? 146 PHE A CZ    1 
ATOM   1181 N  N     . ALA A 1 149 ? -6.94631  28.03633 5.36106  1.000 35.15950  ? 147 ALA A N     1 
ATOM   1182 C  CA    . ALA A 1 149 ? -6.31292  29.34954 5.42091  1.000 36.08355  ? 147 ALA A CA    1 
ATOM   1183 C  C     . ALA A 1 149 ? -7.25686  30.43706 5.93725  1.000 41.02969  ? 147 ALA A C     1 
ATOM   1184 O  O     . ALA A 1 149 ? -6.83010  31.32427 6.68787  1.000 48.33291  ? 147 ALA A O     1 
ATOM   1185 C  CB    . ALA A 1 149 ? -5.76659  29.71617 4.03955  1.000 40.86194  ? 147 ALA A CB    1 
ATOM   1186 N  N     . ASP A 1 150 ? -8.53386  30.40145 5.55145  1.000 41.21543  ? 148 ASP A N     1 
ATOM   1187 C  CA    . ASP A 1 150 ? -9.45015  31.48506 5.89026  1.000 47.36034  ? 148 ASP A CA    1 
ATOM   1188 C  C     . ASP A 1 150 ? -10.31956 31.19824 7.11654  1.000 45.28452  ? 148 ASP A C     1 
ATOM   1189 O  O     . ASP A 1 150 ? -11.22215 31.98567 7.41682  1.000 49.67764  ? 148 ASP A O     1 
ATOM   1190 C  CB    . ASP A 1 150 ? -10.33670 31.80964 4.68338  1.000 48.52077  ? 148 ASP A CB    1 
ATOM   1191 N  N     . ARG A 1 151 ? -10.06813 30.11290 7.83917  1.000 36.77416  ? 149 ARG A N     1 
ATOM   1192 C  CA    . ARG A 1 151 ? -10.95728 29.68358 8.91471  1.000 40.64139  ? 149 ARG A CA    1 
ATOM   1193 C  C     . ARG A 1 151 ? -10.52723 30.26895 10.25380 1.000 39.86253  ? 149 ARG A C     1 
ATOM   1194 O  O     . ARG A 1 151 ? -9.34657  30.21910 10.61469 1.000 40.77318  ? 149 ARG A O     1 
ATOM   1195 C  CB    . ARG A 1 151 ? -11.00132 28.15771 8.99722  1.000 37.43453  ? 149 ARG A CB    1 
ATOM   1196 C  CG    . ARG A 1 151 ? -11.86059 27.53275 7.89545  1.000 39.91527  ? 149 ARG A CG    1 
ATOM   1197 C  CD    . ARG A 1 151 ? -13.35201 27.62987 8.21766  1.000 39.83642  ? 149 ARG A CD    1 
ATOM   1198 N  NE    . ARG A 1 151 ? -13.67983 26.96177 9.46966  1.000 43.33087  ? 149 ARG A NE    1 
ATOM   1199 C  CZ    . ARG A 1 151 ? -13.76568 25.64668 9.60862  1.000 39.81435  ? 149 ARG A CZ    1 
ATOM   1200 N  NH1   . ARG A 1 151 ? -13.57213 24.82974 8.58354  1.000 41.50493  ? 149 ARG A NH1   1 
ATOM   1201 N  NH2   . ARG A 1 151 ? -14.04390 25.13900 10.80394 1.000 40.75934  ? 149 ARG A NH2   1 
ATOM   1202 N  N     . GLU A 1 152 ? -11.50363 30.78838 11.00011 1.000 44.38713  ? 150 GLU A N     1 
ATOM   1203 C  CA    . GLU A 1 152 ? -11.21878 31.44623 12.27142 1.000 42.12349  ? 150 GLU A CA    1 
ATOM   1204 C  C     . GLU A 1 152 ? -10.87633 30.42955 13.34600 1.000 41.75247  ? 150 GLU A C     1 
ATOM   1205 O  O     . GLU A 1 152 ? -9.94977  30.63723 14.13996 1.000 43.97881  ? 150 GLU A O     1 
ATOM   1206 C  CB    . GLU A 1 152 ? -12.42476 32.27593 12.70244 1.000 46.07557  ? 150 GLU A CB    1 
ATOM   1207 C  CG    . GLU A 1 152 ? -12.79818 33.38776 11.73742 1.000 50.67314  ? 150 GLU A CG    1 
ATOM   1208 C  CD    . GLU A 1 152 ? -12.98656 34.72800 12.41536 1.000 62.97600  ? 150 GLU A CD    1 
ATOM   1209 O  OE1   . GLU A 1 152 ? -13.18705 34.74730 13.64954 1.000 70.63605  ? 150 GLU A OE1   1 
ATOM   1210 O  OE2   . GLU A 1 152 ? -12.96313 35.75881 11.70776 1.000 69.14258  ? 150 GLU A OE2   1 
ATOM   1211 N  N     . LYS A 1 153 ? -11.64122 29.34100 13.41386 1.000 42.80707  ? 151 LYS A N     1 
ATOM   1212 C  CA    . LYS A 1 153 ? -11.43948 28.29291 14.41017 1.000 38.80687  ? 151 LYS A CA    1 
ATOM   1213 C  C     . LYS A 1 153 ? -11.72943 26.95153 13.75664 1.000 42.09436  ? 151 LYS A C     1 
ATOM   1214 O  O     . LYS A 1 153 ? -12.75062 26.80091 13.07323 1.000 41.47170  ? 151 LYS A O     1 
ATOM   1215 C  CB    . LYS A 1 153 ? -12.34219 28.48438 15.63823 1.000 44.86425  ? 151 LYS A CB    1 
ATOM   1216 C  CG    . LYS A 1 153 ? -12.05739 29.74024 16.45368 1.000 53.49244  ? 151 LYS A CG    1 
ATOM   1217 C  CD    . LYS A 1 153 ? -10.55976 29.88758 16.79084 1.000 54.35079  ? 151 LYS A CD    1 
ATOM   1218 C  CE    . LYS A 1 153 ? -10.34338 30.48826 18.18318 1.000 54.26809  ? 151 LYS A CE    1 
ATOM   1219 N  NZ    . LYS A 1 153 ? -9.35200  29.73495 19.01130 1.000 48.13141  ? 151 LYS A NZ    1 
ATOM   1220 N  N     . VAL A 1 154 ? -10.83341 25.98998 13.97119 1.000 37.16962  ? 152 VAL A N     1 
ATOM   1221 C  CA    . VAL A 1 154 ? -10.88518 24.67846 13.33450 1.000 33.27084  ? 152 VAL A CA    1 
ATOM   1222 C  C     . VAL A 1 154 ? -10.53610 23.63612 14.38199 1.000 32.19950  ? 152 VAL A C     1 
ATOM   1223 O  O     . VAL A 1 154 ? -9.49304  23.73628 15.03417 1.000 32.33634  ? 152 VAL A O     1 
ATOM   1224 C  CB    . VAL A 1 154 ? -9.90784  24.57881 12.14648 1.000 32.19217  ? 152 VAL A CB    1 
ATOM   1225 C  CG1   . VAL A 1 154 ? -10.05062 23.22924 11.45079 1.000 35.58342  ? 152 VAL A CG1   1 
ATOM   1226 C  CG2   . VAL A 1 154 ? -10.11895 25.73703 11.17915 1.000 33.14613  ? 152 VAL A CG2   1 
ATOM   1227 N  N     . SER A 1 155 ? -11.39587 22.64141 14.55181 1.000 32.68420  ? 153 SER A N     1 
ATOM   1228 C  CA    . SER A 1 155 ? -11.11626 21.61079 15.54017 1.000 32.52938  ? 153 SER A CA    1 
ATOM   1229 C  C     . SER A 1 155 ? -10.22944 20.52427 14.94518 1.000 34.88354  ? 153 SER A C     1 
ATOM   1230 O  O     . SER A 1 155 ? -10.17233 20.33124 13.72497 1.000 33.35930  ? 153 SER A O     1 
ATOM   1231 C  CB    . SER A 1 155 ? -12.41318 20.99156 16.05783 1.000 37.35544  ? 153 SER A CB    1 
ATOM   1232 O  OG    . SER A 1 155 ? -12.96454 20.14448 15.07069 1.000 40.35571  ? 153 SER A OG    1 
ATOM   1233 N  N     . ASP A 1 156 ? -9.53177  19.80800 15.83122 1.000 31.37456  ? 154 ASP A N     1 
ATOM   1234 C  CA    . ASP A 1 156 ? -8.74285  18.65517 15.40692 1.000 29.66589  ? 154 ASP A CA    1 
ATOM   1235 C  C     . ASP A 1 156 ? -9.60978  17.60820 14.72122 1.000 27.82842  ? 154 ASP A C     1 
ATOM   1236 O  O     . ASP A 1 156 ? -9.12193  16.85906 13.86593 1.000 28.35745  ? 154 ASP A O     1 
ATOM   1237 C  CB    . ASP A 1 156 ? -8.02820  18.03372 16.60785 1.000 25.93462  ? 154 ASP A CB    1 
ATOM   1238 C  CG    . ASP A 1 156 ? -6.77080  18.78896 16.99655 1.000 33.70171  ? 154 ASP A CG    1 
ATOM   1239 O  OD1   . ASP A 1 156 ? -6.47723  19.84286 16.40211 1.000 28.77170  ? 154 ASP A OD1   1 
ATOM   1240 O  OD2   . ASP A 1 156 ? -6.06749  18.32850 17.91199 1.000 33.81382  ? 154 ASP A OD2   1 
ATOM   1241 N  N     . ARG A 1 157 ? -10.88175 17.52141 15.10383 1.000 30.92012  ? 155 ARG A N     1 
ATOM   1242 C  CA    . ARG A 1 157 ? -11.80837 16.62443 14.42924 1.000 29.12550  ? 155 ARG A CA    1 
ATOM   1243 C  C     . ARG A 1 157 ? -11.83083 16.87871 12.92778 1.000 33.18118  ? 155 ARG A C     1 
ATOM   1244 O  O     . ARG A 1 157 ? -11.91465 15.94019 12.12573 1.000 34.06981  ? 155 ARG A O     1 
ATOM   1245 C  CB    . ARG A 1 157 ? -13.20412 16.81651 15.02414 1.000 32.19216  ? 155 ARG A CB    1 
ATOM   1246 C  CG    . ARG A 1 157 ? -14.23058 15.85562 14.52045 1.000 41.12500  ? 155 ARG A CG    1 
ATOM   1247 C  CD    . ARG A 1 157 ? -15.33572 15.65175 15.56227 1.000 45.68915  ? 155 ARG A CD    1 
ATOM   1248 N  NE    . ARG A 1 157 ? -15.32130 14.27303 16.02751 1.000 48.25516  ? 155 ARG A NE    1 
ATOM   1249 C  CZ    . ARG A 1 157 ? -15.85157 13.27035 15.34457 1.000 43.26447  ? 155 ARG A CZ    1 
ATOM   1250 N  NH1   . ARG A 1 157 ? -16.49731 13.47654 14.20860 1.000 46.24620  ? 155 ARG A NH1   1 
ATOM   1251 N  NH2   . ARG A 1 157 ? -15.73584 12.03221 15.81675 1.000 54.63113  ? 155 ARG A NH2   1 
ATOM   1252 N  N     . GLU A 1 158 ? -11.79217 18.14852 12.52675 1.000 31.92753  ? 156 GLU A N     1 
ATOM   1253 C  CA    . GLU A 1 158 ? -11.83424 18.46166 11.10501 1.000 31.36768  ? 156 GLU A CA    1 
ATOM   1254 C  C     . GLU A 1 158 ? -10.50642 18.17364 10.42756 1.000 31.28860  ? 156 GLU A C     1 
ATOM   1255 O  O     . GLU A 1 158 ? -10.48221 17.84028 9.22713  1.000 31.75869  ? 156 GLU A O     1 
ATOM   1256 C  CB    . GLU A 1 158 ? -12.22023 19.91820 10.90308 1.000 39.73107  ? 156 GLU A CB    1 
ATOM   1257 C  CG    . GLU A 1 158 ? -13.38070 20.35231 11.77313 1.000 46.21770  ? 156 GLU A CG    1 
ATOM   1258 C  CD    . GLU A 1 158 ? -13.75287 21.79611 11.54640 1.000 47.19378  ? 156 GLU A CD    1 
ATOM   1259 O  OE1   . GLU A 1 158 ? -13.94663 22.17412 10.36289 1.000 48.34631  ? 156 GLU A OE1   1 
ATOM   1260 O  OE2   . GLU A 1 158 ? -13.81448 22.54766 12.55263 1.000 49.33312  ? 156 GLU A OE2   1 
ATOM   1261 N  N     . LEU A 1 159 ? -9.39961  18.31323 11.17093 1.000 30.58023  ? 157 LEU A N     1 
ATOM   1262 C  CA    . LEU A 1 159 ? -8.08222  18.06467 10.59804 1.000 27.68517  ? 157 LEU A CA    1 
ATOM   1263 C  C     . LEU A 1 159 ? -7.79942  16.57703 10.45212 1.000 28.79067  ? 157 LEU A C     1 
ATOM   1264 O  O     . LEU A 1 159 ? -7.12535  16.16730 9.50248  1.000 31.02924  ? 157 LEU A O     1 
ATOM   1265 C  CB    . LEU A 1 159 ? -6.98658  18.71436 11.45684 1.000 27.13407  ? 157 LEU A CB    1 
ATOM   1266 C  CG    . LEU A 1 159 ? -7.08240  20.20474 11.77879 1.000 26.67889  ? 157 LEU A CG    1 
ATOM   1267 C  CD1   . LEU A 1 159 ? -5.89643  20.64512 12.67415 1.000 27.81777  ? 157 LEU A CD1   1 
ATOM   1268 C  CD2   . LEU A 1 159 ? -7.11745  21.00656 10.48416 1.000 30.08373  ? 157 LEU A CD2   1 
ATOM   1269 N  N     . TRP A 1 160 ? -8.27595  15.76327 11.39669 1.000 30.41371  ? 158 TRP A N     1 
ATOM   1270 C  CA    . TRP A 1 160 ? -7.90812  14.34798 11.44587 1.000 31.89396  ? 158 TRP A CA    1 
ATOM   1271 C  C     . TRP A 1 160 ? -8.02947  13.62459 10.10378 1.000 30.75459  ? 158 TRP A C     1 
ATOM   1272 O  O     . TRP A 1 160 ? -7.07703  12.92786 9.72075  1.000 29.98106  ? 158 TRP A O     1 
ATOM   1273 C  CB    . TRP A 1 160 ? -8.77455  13.62686 12.48526 1.000 34.98888  ? 158 TRP A CB    1 
ATOM   1274 C  CG    . TRP A 1 160 ? -8.20894  12.30818 12.90718 1.000 35.13795  ? 158 TRP A CG    1 
ATOM   1275 C  CD1   . TRP A 1 160 ? -8.56959  11.07626 12.43062 1.000 41.92370  ? 158 TRP A CD1   1 
ATOM   1276 C  CD2   . TRP A 1 160 ? -7.31617  12.06172 14.00104 1.000 39.11866  ? 158 TRP A CD2   1 
ATOM   1277 N  NE1   . TRP A 1 160 ? -7.87150  10.08801 13.08768 1.000 39.02658  ? 158 TRP A NE1   1 
ATOM   1278 C  CE2   . TRP A 1 160 ? -7.11153  10.66316 14.06946 1.000 37.48701  ? 158 TRP A CE2   1 
ATOM   1279 C  CE3   . TRP A 1 160 ? -6.64602  12.88503 14.90932 1.000 39.36113  ? 158 TRP A CE3   1 
ATOM   1280 C  CZ2   . TRP A 1 160 ? -6.25795  10.07608 15.00459 1.000 36.93884  ? 158 TRP A CZ2   1 
ATOM   1281 C  CZ3   . TRP A 1 160 ? -5.79643  12.29687 15.83963 1.000 44.11758  ? 158 TRP A CZ3   1 
ATOM   1282 C  CH2   . TRP A 1 160 ? -5.61458  10.90791 15.88019 1.000 40.41589  ? 158 TRP A CH2   1 
ATOM   1283 N  N     . PRO A 1 161 ? -9.15348  13.68847 9.38239  1.000 29.91211  ? 159 PRO A N     1 
ATOM   1284 C  CA    . PRO A 1 161 ? -9.25956  12.90774 8.13485  1.000 29.35614  ? 159 PRO A CA    1 
ATOM   1285 C  C     . PRO A 1 161 ? -8.27220  13.35791 7.07942  1.000 32.24517  ? 159 PRO A C     1 
ATOM   1286 O  O     . PRO A 1 161 ? -7.86353  12.55041 6.23057  1.000 31.02830  ? 159 PRO A O     1 
ATOM   1287 C  CB    . PRO A 1 161 ? -10.71150 13.14675 7.68358  1.000 33.31117  ? 159 PRO A CB    1 
ATOM   1288 C  CG    . PRO A 1 161 ? -11.41584 13.62698 8.87658  1.000 36.47261  ? 159 PRO A CG    1 
ATOM   1289 C  CD    . PRO A 1 161 ? -10.41837 14.36977 9.69989  1.000 31.43335  ? 159 PRO A CD    1 
ATOM   1290 N  N     . LEU A 1 162 ? -7.89036  14.63494 7.09871  1.000 28.96329  ? 160 LEU A N     1 
ATOM   1291 C  CA    . LEU A 1 162 ? -6.93926  15.14137 6.11145  1.000 31.75130  ? 160 LEU A CA    1 
ATOM   1292 C  C     . LEU A 1 162 ? -5.52069  14.70390 6.44208  1.000 27.98663  ? 160 LEU A C     1 
ATOM   1293 O  O     . LEU A 1 162 ? -4.74794  14.35711 5.53815  1.000 28.74623  ? 160 LEU A O     1 
ATOM   1294 C  CB    . LEU A 1 162 ? -7.03163  16.66737 6.02296  1.000 29.18665  ? 160 LEU A CB    1 
ATOM   1295 C  CG    . LEU A 1 162 ? -8.33101  17.16376 5.37386  1.000 32.64110  ? 160 LEU A CG    1 
ATOM   1296 C  CD1   . LEU A 1 162 ? -8.60661  18.59987 5.74666  1.000 34.97542  ? 160 LEU A CD1   1 
ATOM   1297 C  CD2   . LEU A 1 162 ? -8.27909  16.99660 3.83524  1.000 34.33287  ? 160 LEU A CD2   1 
ATOM   1298 N  N     . VAL A 1 163 ? -5.16813  14.69837 7.72843  1.000 27.99022  ? 161 VAL A N     1 
ATOM   1299 C  CA    . VAL A 1 163 ? -3.88596  14.13200 8.13358  1.000 26.65478  ? 161 VAL A CA    1 
ATOM   1300 C  C     . VAL A 1 163 ? -3.82897  12.65671 7.76976  1.000 30.92645  ? 161 VAL A C     1 
ATOM   1301 O  O     . VAL A 1 163 ? -2.82105  12.17192 7.24408  1.000 27.64668  ? 161 VAL A O     1 
ATOM   1302 C  CB    . VAL A 1 163 ? -3.66277  14.35917 9.63842  1.000 27.00318  ? 161 VAL A CB    1 
ATOM   1303 C  CG1   . VAL A 1 163 ? -2.29830  13.84438 10.04525 1.000 24.05358  ? 161 VAL A CG1   1 
ATOM   1304 C  CG2   . VAL A 1 163 ? -3.79784  15.84152 9.95196  1.000 24.95333  ? 161 VAL A CG2   1 
ATOM   1305 N  N     . GLU A 1 164 ? -4.91866  11.92345 8.02450  1.000 28.22350  ? 162 GLU A N     1 
ATOM   1306 C  CA    . GLU A 1 164 ? -4.95510  10.50383 7.68391  1.000 33.22843  ? 162 GLU A CA    1 
ATOM   1307 C  C     . GLU A 1 164 ? -4.81160  10.28998 6.18571  1.000 33.14953  ? 162 GLU A C     1 
ATOM   1308 O  O     . GLU A 1 164 ? -4.04899  9.42291  5.73643  1.000 33.37581  ? 162 GLU A O     1 
ATOM   1309 C  CB    . GLU A 1 164 ? -6.25704  9.86888  8.17958  1.000 36.20244  ? 162 GLU A CB    1 
ATOM   1310 C  CG    . GLU A 1 164 ? -6.17696  8.35356  8.27233  1.000 45.01064  ? 162 GLU A CG    1 
ATOM   1311 C  CD    . GLU A 1 164 ? -7.39593  7.73951  8.92704  1.000 57.58323  ? 162 GLU A CD    1 
ATOM   1312 O  OE1   . GLU A 1 164 ? -7.47909  6.49415  8.98257  1.000 64.73238  ? 162 GLU A OE1   1 
ATOM   1313 O  OE2   . GLU A 1 164 ? -8.26662  8.50252  9.39365  1.000 65.35684  ? 162 GLU A OE2   1 
ATOM   1314 N  N     . ALA A 1 165 ? -5.54978  11.07361 5.39583  1.000 30.87384  ? 163 ALA A N     1 
ATOM   1315 C  CA    . ALA A 1 165 ? -5.59023  10.87078 3.95509  1.000 30.76361  ? 163 ALA A CA    1 
ATOM   1316 C  C     . ALA A 1 165 ? -4.25931  11.20129 3.29886  1.000 30.54085  ? 163 ALA A C     1 
ATOM   1317 O  O     . ALA A 1 165 ? -3.93346  10.61730 2.25825  1.000 37.15695  ? 163 ALA A O     1 
ATOM   1318 C  CB    . ALA A 1 165 ? -6.69625  11.72119 3.33993  1.000 32.54205  ? 163 ALA A CB    1 
ATOM   1319 N  N     . THR A 1 166 ? -3.49997  12.15176 3.85274  1.000 30.55784  ? 164 THR A N     1 
ATOM   1320 C  CA    . THR A 1 166 ? -2.27997  12.59599 3.18745  1.000 28.12925  ? 164 THR A CA    1 
ATOM   1321 C  C     . THR A 1 166 ? -1.03534  11.85578 3.64432  1.000 31.81619  ? 164 THR A C     1 
ATOM   1322 O  O     . THR A 1 166 ? 0.02196   12.01941 3.02794  1.000 32.31720  ? 164 THR A O     1 
ATOM   1323 C  CB    . THR A 1 166 ? -2.05270  14.09780 3.37591  1.000 26.72152  ? 164 THR A CB    1 
ATOM   1324 O  OG1   . THR A 1 166 ? -2.09944  14.43264 4.76980  1.000 27.54120  ? 164 THR A OG1   1 
ATOM   1325 C  CG2   . THR A 1 166 ? -3.12311  14.88404 2.60559  1.000 26.88991  ? 164 THR A CG2   1 
ATOM   1326 N  N     . CYS A 1 167 ? -1.12842  11.03505 4.66685  1.000 29.76568  ? 165 CYS A N     1 
ATOM   1327 C  CA    . CYS A 1 167 ? 0.04857   10.30591 5.09669  1.000 30.82786  ? 165 CYS A CA    1 
ATOM   1328 C  C     . CYS A 1 167 ? 0.38841   9.24073  4.06459  1.000 31.72842  ? 165 CYS A C     1 
ATOM   1329 O  O     . CYS A 1 167 ? -0.46455  8.39421  3.76133  1.000 34.59141  ? 165 CYS A O     1 
ATOM   1330 C  CB    . CYS A 1 167 ? -0.18702  9.66674  6.44819  1.000 29.84062  ? 165 CYS A CB    1 
ATOM   1331 S  SG    . CYS A 1 167 ? 1.27749   8.81577  7.07489  1.000 32.35170  ? 165 CYS A SG    1 
ATOM   1332 N  N     . PRO A 1 168 ? 1.60280   9.23582  3.51038  1.000 31.15696  ? 166 PRO A N     1 
ATOM   1333 C  CA    . PRO A 1 168 ? 1.97372   8.19347  2.55003  1.000 34.50226  ? 166 PRO A CA    1 
ATOM   1334 C  C     . PRO A 1 168 ? 2.12646   6.84016  3.22431  1.000 36.74503  ? 166 PRO A C     1 
ATOM   1335 O  O     . PRO A 1 168 ? 2.56336   6.72878  4.37235  1.000 35.85124  ? 166 PRO A O     1 
ATOM   1336 C  CB    . PRO A 1 168 ? 3.30991   8.69093  1.99116  1.000 33.16473  ? 166 PRO A CB    1 
ATOM   1337 C  CG    . PRO A 1 168 ? 3.91441   9.43631  3.14183  1.000 37.39295  ? 166 PRO A CG    1 
ATOM   1338 C  CD    . PRO A 1 168 ? 2.73782   10.12829 3.82043  1.000 29.15910  ? 166 PRO A CD    1 
ATOM   1339 N  N     . GLU A 1 169 ? 1.77961   5.79142  2.48156  1.000 41.19470  ? 167 GLU A N     1 
ATOM   1340 C  CA    . GLU A 1 169 ? 1.80931   4.45348  3.05958  1.000 41.71407  ? 167 GLU A CA    1 
ATOM   1341 C  C     . GLU A 1 169 ? 3.22886   4.00012  3.39910  1.000 45.30002  ? 167 GLU A C     1 
ATOM   1342 O  O     . GLU A 1 169 ? 3.45008   3.39007  4.45202  1.000 42.14197  ? 167 GLU A O     1 
ATOM   1343 C  CB    . GLU A 1 169 ? 1.14373   3.46282  2.11395  1.000 46.09694  ? 167 GLU A CB    1 
ATOM   1344 C  CG    . GLU A 1 169 ? -0.22682  3.04923  2.59475  1.000 51.23155  ? 167 GLU A CG    1 
ATOM   1345 C  CD    . GLU A 1 169 ? -0.16008  1.97734  3.65989  1.000 57.80591  ? 167 GLU A CD    1 
ATOM   1346 O  OE1   . GLU A 1 169 ? 0.87642   1.28619  3.74359  1.000 68.19280  ? 167 GLU A OE1   1 
ATOM   1347 N  N     . ASP A 1 170 ? 4.20376   4.27033  2.52721  1.000 41.56344  ? 168 ASP A N     1 
ATOM   1348 C  CA    . ASP A 1 170 ? 5.55229   3.73904  2.71148  1.000 44.56392  ? 168 ASP A CA    1 
ATOM   1349 C  C     . ASP A 1 170 ? 6.58374   4.80277  3.04744  1.000 41.58849  ? 168 ASP A C     1 
ATOM   1350 O  O     . ASP A 1 170 ? 7.78547   4.54373  2.93495  1.000 50.97867  ? 168 ASP A O     1 
ATOM   1351 C  CB    . ASP A 1 170 ? 6.02282   2.96693  1.47625  1.000 47.51578  ? 168 ASP A CB    1 
ATOM   1352 C  CG    . ASP A 1 170 ? 4.93838   2.12926  0.86075  1.000 62.95951  ? 168 ASP A CG    1 
ATOM   1353 O  OD1   . ASP A 1 170 ? 4.71412   1.00873  1.37329  1.000 67.97912  ? 168 ASP A OD1   1 
ATOM   1354 O  OD2   . ASP A 1 170 ? 4.33460   2.56713  -0.14394 1.000 73.57253  ? 168 ASP A OD2   1 
ATOM   1355 N  N     . ASP A 1 171 ? 6.16144   5.97998  3.47885  1.000 38.91047  ? 169 ASP A N     1 
ATOM   1356 C  CA    . ASP A 1 171 ? 7.14935   7.02068  3.71518  1.000 41.22337  ? 169 ASP A CA    1 
ATOM   1357 C  C     . ASP A 1 171 ? 6.82818   7.87835  4.93488  1.000 32.54742  ? 169 ASP A C     1 
ATOM   1358 O  O     . ASP A 1 171 ? 7.16148   9.06571  4.96365  1.000 33.19277  ? 169 ASP A O     1 
ATOM   1359 C  CB    . ASP A 1 171 ? 7.28596   7.89607  2.47679  1.000 40.59746  ? 169 ASP A CB    1 
ATOM   1360 C  CG    . ASP A 1 171 ? 8.60308   8.60253  2.43077  1.000 46.99957  ? 169 ASP A CG    1 
ATOM   1361 O  OD1   . ASP A 1 171 ? 9.59301   8.02854  2.95735  1.000 41.21787  ? 169 ASP A OD1   1 
ATOM   1362 O  OD2   . ASP A 1 171 ? 8.64078   9.72016  1.86698  1.000 45.98696  ? 169 ASP A OD2   1 
ATOM   1363 N  N     . ALA A 1 172 ? 6.21264   7.29099  5.96065  1.000 33.57910  ? 170 ALA A N     1 
ATOM   1364 C  CA    . ALA A 1 172 ? 5.66139   8.09816  7.04438  1.000 28.15358  ? 170 ALA A CA    1 
ATOM   1365 C  C     . ALA A 1 172 ? 6.74506   8.85655  7.80165  1.000 29.40653  ? 170 ALA A C     1 
ATOM   1366 O  O     . ALA A 1 172 ? 6.53937   10.01026 8.20090  1.000 28.29357  ? 170 ALA A O     1 
ATOM   1367 C  CB    . ALA A 1 172 ? 4.86665   7.20954  8.00130  1.000 30.75152  ? 170 ALA A CB    1 
ATOM   1368 N  N     . ARG A 1 173 ? 7.89011   8.21850  8.05308  1.000 27.97259  ? 171 ARG A N     1 
ATOM   1369 C  CA    . ARG A 1 173 ? 8.92508   8.88362  8.84041  1.000 28.73625  ? 171 ARG A CA    1 
ATOM   1370 C  C     . ARG A 1 173 ? 9.36031   10.18015 8.16385  1.000 27.49584  ? 171 ARG A C     1 
ATOM   1371 O  O     . ARG A 1 173 ? 9.33633   11.25439 8.77677  1.000 26.43333  ? 171 ARG A O     1 
ATOM   1372 C  CB    . ARG A 1 173 ? 10.12257  7.95417  9.04468  1.000 30.85473  ? 171 ARG A CB    1 
ATOM   1373 C  CG    . ARG A 1 173 ? 11.37499  8.67801  9.56648  1.000 31.59887  ? 171 ARG A CG    1 
ATOM   1374 C  CD    . ARG A 1 173 ? 12.61577  7.79475  9.44444  1.000 35.36609  ? 171 ARG A CD    1 
ATOM   1375 N  NE    . ARG A 1 173 ? 12.60160  6.67868  10.38142 1.000 38.65585  ? 171 ARG A NE    1 
ATOM   1376 C  CZ    . ARG A 1 173 ? 13.46075  5.66908  10.34533 1.000 47.53752  ? 171 ARG A CZ    1 
ATOM   1377 N  NH1   . ARG A 1 173 ? 14.37883  5.57204  9.39196  1.000 50.08757  ? 171 ARG A NH1   1 
ATOM   1378 N  NH2   . ARG A 1 173 ? 13.39283  4.72623  11.27907 1.000 50.45976  ? 171 ARG A NH2   1 
ATOM   1379 N  N     . ALA A 1 174 ? 9.73824   10.09925 6.88091  1.000 29.39817  ? 172 ALA A N     1 
ATOM   1380 C  CA    . ALA A 1 174 ? 10.21615  11.28378 6.17371  1.000 28.66554  ? 172 ALA A CA    1 
ATOM   1381 C  C     . ALA A 1 174 ? 9.11438   12.31770 6.00637  1.000 29.39174  ? 172 ALA A C     1 
ATOM   1382 O  O     . ALA A 1 174 ? 9.38546   13.52542 6.05408  1.000 27.94594  ? 172 ALA A O     1 
ATOM   1383 C  CB    . ALA A 1 174 ? 10.79690  10.88620 4.80583  1.000 28.84302  ? 172 ALA A CB    1 
ATOM   1384 N  N     . TRP A 1 175 ? 7.86894   11.85981 5.83152  1.000 25.54250  ? 173 TRP A N     1 
ATOM   1385 C  CA    . TRP A 1 175 ? 6.73271   12.76510 5.69651  1.000 25.99342  ? 173 TRP A CA    1 
ATOM   1386 C  C     . TRP A 1 175 ? 6.52399   13.58026 6.96320  1.000 25.34469  ? 173 TRP A C     1 
ATOM   1387 O  O     . TRP A 1 175 ? 6.34925   14.80193 6.91866  1.000 25.33192  ? 173 TRP A O     1 
ATOM   1388 C  CB    . TRP A 1 175 ? 5.48756   11.94638 5.36243  1.000 26.18411  ? 173 TRP A CB    1 
ATOM   1389 C  CG    . TRP A 1 175 ? 4.17286   12.68366 5.42262  1.000 24.99626  ? 173 TRP A CG    1 
ATOM   1390 C  CD1   . TRP A 1 175 ? 3.16657   12.49649 6.33942  1.000 27.06650  ? 173 TRP A CD1   1 
ATOM   1391 C  CD2   . TRP A 1 175 ? 3.69661   13.68202 4.50416  1.000 24.17042  ? 173 TRP A CD2   1 
ATOM   1392 N  NE1   . TRP A 1 175 ? 2.10103   13.32517 6.04304  1.000 27.67408  ? 173 TRP A NE1   1 
ATOM   1393 C  CE2   . TRP A 1 175 ? 2.40954   14.07464 4.94114  1.000 26.95628  ? 173 TRP A CE2   1 
ATOM   1394 C  CE3   . TRP A 1 175 ? 4.24636   14.30391 3.38279  1.000 27.78675  ? 173 TRP A CE3   1 
ATOM   1395 C  CZ2   . TRP A 1 175 ? 1.65711   15.05223 4.28712  1.000 26.28869  ? 173 TRP A CZ2   1 
ATOM   1396 C  CZ3   . TRP A 1 175 ? 3.49894   15.28078 2.72916  1.000 27.47678  ? 173 TRP A CZ3   1 
ATOM   1397 C  CH2   . TRP A 1 175 ? 2.21865   15.64120 3.18331  1.000 30.08221  ? 173 TRP A CH2   1 
ATOM   1398 N  N     . TYR A 1 176 ? 6.54314   12.92365 8.11497  1.000 23.75272  ? 174 TYR A N     1 
ATOM   1399 C  CA    . TYR A 1 176 ? 6.25601   13.68041 9.31406  1.000 24.31196  ? 174 TYR A CA    1 
ATOM   1400 C  C     . TYR A 1 176 ? 7.44812   14.53317 9.74571  1.000 23.11375  ? 174 TYR A C     1 
ATOM   1401 O  O     . TYR A 1 176 ? 7.24803   15.58450 10.36268 1.000 23.41664  ? 174 TYR A O     1 
ATOM   1402 C  CB    . TYR A 1 176 ? 5.79268   12.73100 10.42059 1.000 24.67259  ? 174 TYR A CB    1 
ATOM   1403 C  CG    . TYR A 1 176 ? 4.32509   12.36853 10.26369 1.000 24.35205  ? 174 TYR A CG    1 
ATOM   1404 C  CD1   . TYR A 1 176 ? 3.35060   13.36661 10.23646 1.000 23.63879  ? 174 TYR A CD1   1 
ATOM   1405 C  CD2   . TYR A 1 176 ? 3.91185   11.04034 10.13154 1.000 22.53197  ? 174 TYR A CD2   1 
ATOM   1406 C  CE1   . TYR A 1 176 ? 1.98896   13.05269 10.08473 1.000 23.66028  ? 174 TYR A CE1   1 
ATOM   1407 C  CE2   . TYR A 1 176 ? 2.53161   10.71326 9.98726  1.000 24.96560  ? 174 TYR A CE2   1 
ATOM   1408 C  CZ    . TYR A 1 176 ? 1.59786   11.72982 9.96965  1.000 23.80387  ? 174 TYR A CZ    1 
ATOM   1409 O  OH    . TYR A 1 176 ? 0.26431   11.43548 9.83206  1.000 26.16092  ? 174 TYR A OH    1 
ATOM   1410 N  N     . TYR A 1 177 ? 8.68021   14.13611 9.39800  1.000 24.94421  ? 175 TYR A N     1 
ATOM   1411 C  CA    . TYR A 1 177 ? 9.80235   15.05182 9.59125  1.000 26.39164  ? 175 TYR A CA    1 
ATOM   1412 C  C     . TYR A 1 177 ? 9.58859   16.32357 8.77962  1.000 25.74313  ? 175 TYR A C     1 
ATOM   1413 O  O     . TYR A 1 177 ? 9.83147   17.43351 9.27111  1.000 23.77001  ? 175 TYR A O     1 
ATOM   1414 C  CB    . TYR A 1 177 ? 11.12336  14.39954 9.17491  1.000 25.16957  ? 175 TYR A CB    1 
ATOM   1415 C  CG    . TYR A 1 177 ? 11.68272  13.34323 10.10018 1.000 27.85283  ? 175 TYR A CG    1 
ATOM   1416 C  CD1   . TYR A 1 177 ? 11.22726  13.19342 11.40359 1.000 27.12775  ? 175 TYR A CD1   1 
ATOM   1417 C  CD2   . TYR A 1 177 ? 12.65860  12.46568 9.63147  1.000 29.46349  ? 175 TYR A CD2   1 
ATOM   1418 C  CE1   . TYR A 1 177 ? 11.77522  12.20311 12.23422 1.000 29.70357  ? 175 TYR A CE1   1 
ATOM   1419 C  CE2   . TYR A 1 177 ? 13.19236  11.48341 10.43775 1.000 30.89088  ? 175 TYR A CE2   1 
ATOM   1420 C  CZ    . TYR A 1 177 ? 12.74008  11.35433 11.72865 1.000 31.87185  ? 175 TYR A CZ    1 
ATOM   1421 O  OH    . TYR A 1 177 ? 13.28182  10.36578 12.50808 1.000 32.46975  ? 175 TYR A OH    1 
ATOM   1422 N  N     . ALA A 1 178 ? 9.09407   16.18200 7.53666  1.000 23.87084  ? 176 ALA A N     1 
ATOM   1423 C  CA    . ALA A 1 178 ? 8.83211   17.35229 6.70696  1.000 26.73323  ? 176 ALA A CA    1 
ATOM   1424 C  C     . ALA A 1 178 ? 7.75045   18.23438 7.32032  1.000 24.69751  ? 176 ALA A C     1 
ATOM   1425 O  O     . ALA A 1 178 ? 7.88209   19.46632 7.34257  1.000 26.03659  ? 176 ALA A O     1 
ATOM   1426 C  CB    . ALA A 1 178 ? 8.42549   16.91349 5.29742  1.000 26.77903  ? 176 ALA A CB    1 
ATOM   1427 N  N     . LEU A 1 179 ? 6.66512   17.62396 7.80816  1.000 23.82873  ? 177 LEU A N     1 
ATOM   1428 C  CA    . LEU A 1 179 ? 5.62080   18.40696 8.45995  1.000 23.99447  ? 177 LEU A CA    1 
ATOM   1429 C  C     . LEU A 1 179 ? 6.15029   19.10552 9.70210  1.000 25.93631  ? 177 LEU A C     1 
ATOM   1430 O  O     . LEU A 1 179 ? 5.85022   20.28575 9.93088  1.000 24.59133  ? 177 LEU A O     1 
ATOM   1431 C  CB    . LEU A 1 179 ? 4.43167   17.51371 8.80837  1.000 22.60711  ? 177 LEU A CB    1 
ATOM   1432 C  CG    . LEU A 1 179 ? 3.58623   17.13719 7.58390  1.000 23.96457  ? 177 LEU A CG    1 
ATOM   1433 C  CD1   . LEU A 1 179 ? 2.59468   16.04015 7.94573  1.000 27.13150  ? 177 LEU A CD1   1 
ATOM   1434 C  CD2   . LEU A 1 179 ? 2.85327   18.37061 7.04577  1.000 26.37767  ? 177 LEU A CD2   1 
ATOM   1435 N  N     . LEU A 1 180 ? 6.93787   18.39251 10.52060 1.000 23.01469  ? 178 LEU A N     1 
ATOM   1436 C  CA    . LEU A 1 180 ? 7.50523   19.00521 11.71631 1.000 23.75262  ? 178 LEU A CA    1 
ATOM   1437 C  C     . LEU A 1 180 ? 8.35720   20.20633 11.35223 1.000 24.15087  ? 178 LEU A C     1 
ATOM   1438 O  O     . LEU A 1 180 ? 8.25516   21.27245 11.96662 1.000 25.07371  ? 178 LEU A O     1 
ATOM   1439 C  CB    . LEU A 1 180 ? 8.34706   17.98343 12.49321 1.000 22.93716  ? 178 LEU A CB    1 
ATOM   1440 C  CG    . LEU A 1 180 ? 7.56483   16.92630 13.28859 1.000 25.18180  ? 178 LEU A CG    1 
ATOM   1441 C  CD1   . LEU A 1 180 ? 8.52741   15.88298 13.84497 1.000 26.71461  ? 178 LEU A CD1   1 
ATOM   1442 C  CD2   . LEU A 1 180 ? 6.78070   17.58097 14.43321 1.000 26.16826  ? 178 LEU A CD2   1 
ATOM   1443 N  N     . ASP A 1 181 ? 9.20666   20.04567 10.34001 1.000 23.85037  ? 179 ASP A N     1 
ATOM   1444 C  CA    . ASP A 1 181 ? 10.15617  21.09090 9.98396  1.000 25.67818  ? 179 ASP A CA    1 
ATOM   1445 C  C     . ASP A 1 181 ? 9.46394   22.27157 9.31444  1.000 25.38487  ? 179 ASP A C     1 
ATOM   1446 O  O     . ASP A 1 181 ? 9.80091   23.43042 9.59018  1.000 26.17968  ? 179 ASP A O     1 
ATOM   1447 C  CB    . ASP A 1 181 ? 11.23419  20.50197 9.07819  1.000 24.61564  ? 179 ASP A CB    1 
ATOM   1448 C  CG    . ASP A 1 181 ? 12.12238  19.49432 9.80152  1.000 29.57038  ? 179 ASP A CG    1 
ATOM   1449 O  OD1   . ASP A 1 181 ? 12.07400  19.45613 11.05254 1.000 29.63006  ? 179 ASP A OD1   1 
ATOM   1450 O  OD2   . ASP A 1 181 ? 12.86096  18.74378 9.11408  1.000 25.87898  ? 179 ASP A OD2   1 
ATOM   1451 N  N     . TYR A 1 182 ? 8.46948   22.00294 8.45715  1.000 24.46786  ? 180 TYR A N     1 
ATOM   1452 C  CA    . TYR A 1 182 ? 7.73745   23.09656 7.82664  1.000 22.15094  ? 180 TYR A CA    1 
ATOM   1453 C  C     . TYR A 1 182 ? 6.87583   23.83463 8.84432  1.000 24.58999  ? 180 TYR A C     1 
ATOM   1454 O  O     . TYR A 1 182 ? 6.81215   25.07154 8.83430  1.000 25.21725  ? 180 TYR A O     1 
ATOM   1455 C  CB    . TYR A 1 182 ? 6.90611   22.53945 6.66596  1.000 22.79075  ? 180 TYR A CB    1 
ATOM   1456 C  CG    . TYR A 1 182 ? 6.13682   23.55414 5.86671  1.000 25.39819  ? 180 TYR A CG    1 
ATOM   1457 C  CD1   . TYR A 1 182 ? 6.66878   24.79524 5.58799  1.000 25.54016  ? 180 TYR A CD1   1 
ATOM   1458 C  CD2   . TYR A 1 182 ? 4.86540   23.25422 5.38800  1.000 28.40617  ? 180 TYR A CD2   1 
ATOM   1459 C  CE1   . TYR A 1 182 ? 5.96159   25.71625 4.83059  1.000 26.10791  ? 180 TYR A CE1   1 
ATOM   1460 C  CE2   . TYR A 1 182 ? 4.14731   24.16820 4.64531  1.000 24.94336  ? 180 TYR A CE2   1 
ATOM   1461 C  CZ    . TYR A 1 182 ? 4.69923   25.40043 4.38107  1.000 26.93967  ? 180 TYR A CZ    1 
ATOM   1462 O  OH    . TYR A 1 182 ? 4.00179   26.33061 3.64527  1.000 29.82019  ? 180 TYR A OH    1 
ATOM   1463 N  N     . GLY A 1 183 ? 6.24157   23.09265 9.75153  1.000 23.03226  ? 181 GLY A N     1 
ATOM   1464 C  CA    . GLY A 1 183 ? 5.43272   23.72704 10.78616 1.000 24.55996  ? 181 GLY A CA    1 
ATOM   1465 C  C     . GLY A 1 183 ? 6.24558   24.65664 11.66598 1.000 23.83259  ? 181 GLY A C     1 
ATOM   1466 O  O     . GLY A 1 183 ? 5.81860   25.77376 11.97747 1.000 25.34206  ? 181 GLY A O     1 
ATOM   1467 N  N     . ALA A 1 184 ? 7.42587   24.20772 12.08964 1.000 25.64668  ? 182 ALA A N     1 
ATOM   1468 C  CA    . ALA A 1 184 ? 8.25442   25.06851 12.93519 1.000 27.00337  ? 182 ALA A CA    1 
ATOM   1469 C  C     . ALA A 1 184 ? 8.67286   26.31282 12.17135 1.000 29.20396  ? 182 ALA A C     1 
ATOM   1470 O  O     . ALA A 1 184 ? 8.72212   27.41766 12.72976 1.000 27.95255  ? 182 ALA A O     1 
ATOM   1471 C  CB    . ALA A 1 184 ? 9.47244   24.30009 13.44287 1.000 27.67840  ? 182 ALA A CB    1 
ATOM   1472 N  N     . HIS A 1 185 ? 8.93464   26.16005 10.87081 1.000 27.90635  ? 183 HIS A N     1 
ATOM   1473 C  CA    . HIS A 1 185 ? 9.27095   27.31352 10.04967 1.000 29.60140  ? 183 HIS A CA    1 
ATOM   1474 C  C     . HIS A 1 185 ? 8.10235   28.29431 9.96573  1.000 26.73632  ? 183 HIS A C     1 
ATOM   1475 O  O     . HIS A 1 185 ? 8.28283   29.50842 10.12373 1.000 29.34264  ? 183 HIS A O     1 
ATOM   1476 C  CB    . HIS A 1 185 ? 9.68934   26.83837 8.65881  1.000 28.35149  ? 183 HIS A CB    1 
ATOM   1477 C  CG    . HIS A 1 185 ? 10.02011  27.95220 7.71903  1.000 35.72970  ? 183 HIS A CG    1 
ATOM   1478 N  ND1   . HIS A 1 185 ? 11.11934  28.76616 7.89315  1.000 36.78286  ? 183 HIS A ND1   1 
ATOM   1479 C  CD2   . HIS A 1 185 ? 9.39606   28.39049 6.59833  1.000 36.86453  ? 183 HIS A CD2   1 
ATOM   1480 C  CE1   . HIS A 1 185 ? 11.16128  29.65515 6.91360  1.000 39.41749  ? 183 HIS A CE1   1 
ATOM   1481 N  NE2   . HIS A 1 185 ? 10.12265  29.45392 6.12093  1.000 38.19712  ? 183 HIS A NE2   1 
ATOM   1482 N  N     . LEU A 1 186 ? 6.89695   27.78547 9.69731  1.000 26.90843  ? 184 LEU A N     1 
ATOM   1483 C  CA    . LEU A 1 186 ? 5.72378   28.65334 9.63453  1.000 27.34375  ? 184 LEU A CA    1 
ATOM   1484 C  C     . LEU A 1 186 ? 5.52670   29.39809 10.94810 1.000 30.38426  ? 184 LEU A C     1 
ATOM   1485 O  O     . LEU A 1 186 ? 5.20710   30.59067 10.96141 1.000 30.14107  ? 184 LEU A O     1 
ATOM   1486 C  CB    . LEU A 1 186 ? 4.47932   27.82812 9.31377  1.000 25.94602  ? 184 LEU A CB    1 
ATOM   1487 C  CG    . LEU A 1 186 ? 4.35823   27.31554 7.87003  1.000 25.60222  ? 184 LEU A CG    1 
ATOM   1488 C  CD1   . LEU A 1 186 ? 3.14616   26.38470 7.76172  1.000 26.28465  ? 184 LEU A CD1   1 
ATOM   1489 C  CD2   . LEU A 1 186 ? 4.28097   28.45925 6.85537  1.000 29.29806  ? 184 LEU A CD2   1 
ATOM   1490 N  N     . LYS A 1 187 ? 5.69354   28.70456 12.06474 1.000 29.22015  ? 185 LYS A N     1 
ATOM   1491 C  CA    . LYS A 1 187 ? 5.54172   29.37435 13.34849 1.000 29.87683  ? 185 LYS A CA    1 
ATOM   1492 C  C     . LYS A 1 187 ? 6.52265   30.53320 13.50627 1.000 32.77342  ? 185 LYS A C     1 
ATOM   1493 O  O     . LYS A 1 187 ? 6.23426   31.48356 14.24241 1.000 34.31708  ? 185 LYS A O     1 
ATOM   1494 C  CB    . LYS A 1 187 ? 5.70778   28.35270 14.47231 1.000 27.94383  ? 185 LYS A CB    1 
ATOM   1495 C  CG    . LYS A 1 187 ? 4.46785   27.50339 14.68934 1.000 25.84026  ? 185 LYS A CG    1 
ATOM   1496 C  CD    . LYS A 1 187 ? 4.77905   26.29092 15.55832 1.000 23.86168  ? 185 LYS A CD    1 
ATOM   1497 C  CE    . LYS A 1 187 ? 3.55633   25.38937 15.72929 1.000 23.99967  ? 185 LYS A CE    1 
ATOM   1498 N  NZ    . LYS A 1 187 ? 2.38587   26.09078 16.38594 1.000 24.53848  ? 185 LYS A NZ    1 
ATOM   1499 N  N     . ALA A 1 188 ? 7.65409   30.50428 12.79917 1.000 27.83102  ? 186 ALA A N     1 
ATOM   1500 C  CA    . ALA A 1 188 ? 8.59197   31.61461 12.85899 1.000 32.11494  ? 186 ALA A CA    1 
ATOM   1501 C  C     . ALA A 1 188 ? 8.24594   32.76481 11.90835 1.000 36.40575  ? 186 ALA A C     1 
ATOM   1502 O  O     . ALA A 1 188 ? 8.46200   33.92891 12.25508 1.000 40.89368  ? 186 ALA A O     1 
ATOM   1503 C  CB    . ALA A 1 188 ? 10.00762  31.10855 12.57087 1.000 33.92196  ? 186 ALA A CB    1 
ATOM   1504 N  N     . VAL A 1 189 ? 7.71129   32.48682 10.71871 1.000 34.80670  ? 187 VAL A N     1 
ATOM   1505 C  CA    . VAL A 1 189 ? 7.63761   33.49152 9.65659  1.000 34.24264  ? 187 VAL A CA    1 
ATOM   1506 C  C     . VAL A 1 189 ? 6.23844   34.04598 9.41923  1.000 36.60243  ? 187 VAL A C     1 
ATOM   1507 O  O     . VAL A 1 189 ? 6.10999   35.05902 8.71144  1.000 41.60761  ? 187 VAL A O     1 
ATOM   1508 C  CB    . VAL A 1 189 ? 8.21098   32.95426 8.32679  1.000 37.02310  ? 187 VAL A CB    1 
ATOM   1509 C  CG1   . VAL A 1 189 ? 9.64477   32.47763 8.53148  1.000 37.97749  ? 187 VAL A CG1   1 
ATOM   1510 C  CG2   . VAL A 1 189 ? 7.32206   31.85927 7.76645  1.000 34.61978  ? 187 VAL A CG2   1 
ATOM   1511 N  N     . VAL A 1 190 ? 5.18810   33.42164 9.94445  1.000 32.90488  ? 188 VAL A N     1 
ATOM   1512 C  CA    . VAL A 1 190 ? 3.84919   33.98952 9.86486  1.000 34.05316  ? 188 VAL A CA    1 
ATOM   1513 C  C     . VAL A 1 190 ? 3.23257   33.95027 11.25754 1.000 32.97235  ? 188 VAL A C     1 
ATOM   1514 O  O     . VAL A 1 190 ? 3.75979   33.32630 12.17827 1.000 32.21403  ? 188 VAL A O     1 
ATOM   1515 C  CB    . VAL A 1 190 ? 2.94536   33.26041 8.84167  1.000 34.36969  ? 188 VAL A CB    1 
ATOM   1516 C  CG1   . VAL A 1 190 ? 3.50674   33.39806 7.43007  1.000 36.24172  ? 188 VAL A CG1   1 
ATOM   1517 C  CG2   . VAL A 1 190 ? 2.78240   31.79209 9.20494  1.000 33.64462  ? 188 VAL A CG2   1 
ATOM   1518 N  N     . ALA A 1 191 ? 2.10308   34.64238 11.40491 1.000 36.25518  ? 189 ALA A N     1 
ATOM   1519 C  CA    . ALA A 1 191 ? 1.34539   34.54568 12.64740 1.000 36.65950  ? 189 ALA A CA    1 
ATOM   1520 C  C     . ALA A 1 191 ? 1.02618   33.08583 12.92886 1.000 32.88725  ? 189 ALA A C     1 
ATOM   1521 O  O     . ALA A 1 191 ? 0.48473   32.38371 12.07008 1.000 33.35063  ? 189 ALA A O     1 
ATOM   1522 C  CB    . ALA A 1 191 ? 0.06196   35.36834 12.54544 1.000 41.45580  ? 189 ALA A CB    1 
ATOM   1523 N  N     . ASN A 1 192 ? 1.40558   32.61676 14.12444 1.000 30.31231  ? 190 ASN A N     1 
ATOM   1524 C  CA    . ASN A 1 192 ? 1.27134   31.21219 14.49382 1.000 27.64686  ? 190 ASN A CA    1 
ATOM   1525 C  C     . ASN A 1 192 ? -0.07363  30.65678 14.03444 1.000 27.46147  ? 190 ASN A C     1 
ATOM   1526 O  O     . ASN A 1 192 ? -1.11744  31.02731 14.58465 1.000 30.96294  ? 190 ASN A O     1 
ATOM   1527 C  CB    . ASN A 1 192 ? 1.44385   31.06965 16.01200 1.000 28.01878  ? 190 ASN A CB    1 
ATOM   1528 C  CG    . ASN A 1 192 ? 1.16939   29.66754 16.51179 1.000 28.25905  ? 190 ASN A CG    1 
ATOM   1529 O  OD1   . ASN A 1 192 ? 1.21014   28.69397 15.74951 1.000 26.53560  ? 190 ASN A OD1   1 
ATOM   1530 N  ND2   . ASN A 1 192 ? 0.91486   29.54763 17.82374 1.000 25.88527  ? 190 ASN A ND2   1 
ATOM   1531 N  N     . PRO A 1 193 ? -0.09670  29.78533 13.01888 1.000 30.13178  ? 191 PRO A N     1 
ATOM   1532 C  CA    . PRO A 1 193 ? -1.39298  29.29533 12.51111 1.000 30.39827  ? 191 PRO A CA    1 
ATOM   1533 C  C     . PRO A 1 193 ? -2.22201  28.56877 13.56402 1.000 27.10909  ? 191 PRO A C     1 
ATOM   1534 O  O     . PRO A 1 193 ? -3.45885  28.56250 13.47538 1.000 29.68408  ? 191 PRO A O     1 
ATOM   1535 C  CB    . PRO A 1 193 ? -0.98188  28.37180 11.35042 1.000 27.50309  ? 191 PRO A CB    1 
ATOM   1536 C  CG    . PRO A 1 193 ? 0.36544   28.93102 10.88652 1.000 26.05866  ? 191 PRO A CG    1 
ATOM   1537 C  CD    . PRO A 1 193 ? 1.03881   29.32841 12.19776 1.000 25.95335  ? 191 PRO A CD    1 
ATOM   1538 N  N     . SER A 1 194 ? -1.58031  27.98176 14.57311 1.000 27.15327  ? 192 SER A N     1 
ATOM   1539 C  CA    . SER A 1 194 ? -2.30261  27.27244 15.62788 1.000 27.22465  ? 192 SER A CA    1 
ATOM   1540 C  C     . SER A 1 194 ? -3.17803  28.18166 16.47841 1.000 29.36222  ? 192 SER A C     1 
ATOM   1541 O  O     . SER A 1 194 ? -4.03657  27.67216 17.21117 1.000 30.04061  ? 192 SER A O     1 
ATOM   1542 C  CB    . SER A 1 194 ? -1.31525  26.52467 16.51497 1.000 27.55057  ? 192 SER A CB    1 
ATOM   1543 O  OG    . SER A 1 194 ? -0.73461  25.43970 15.80079 1.000 30.44312  ? 192 SER A OG    1 
ATOM   1544 N  N     . ARG A 1 195 ? -3.00874  29.50360 16.39086 1.000 27.68702  ? 193 ARG A N     1 
ATOM   1545 C  CA    . ARG A 1 195 ? -3.95125  30.40027 17.04763 1.000 30.35053  ? 193 ARG A CA    1 
ATOM   1546 C  C     . ARG A 1 195 ? -5.36006  30.25368 16.49234 1.000 33.64488  ? 193 ARG A C     1 
ATOM   1547 O  O     . ARG A 1 195 ? -6.32190  30.65353 17.15778 1.000 35.08446  ? 193 ARG A O     1 
ATOM   1548 C  CB    . ARG A 1 195 ? -3.49880  31.84774 16.89761 1.000 33.73512  ? 193 ARG A CB    1 
ATOM   1549 C  CG    . ARG A 1 195 ? -2.22925  32.14560 17.65009 1.000 31.44384  ? 193 ARG A CG    1 
ATOM   1550 C  CD    . ARG A 1 195 ? -1.72240  33.52733 17.32437 1.000 35.20244  ? 193 ARG A CD    1 
ATOM   1551 N  NE    . ARG A 1 195 ? -0.54402  33.85439 18.11872 1.000 34.98332  ? 193 ARG A NE    1 
ATOM   1552 C  CZ    . ARG A 1 195 ? 0.04204   35.04111 18.12701 1.000 38.16141  ? 193 ARG A CZ    1 
ATOM   1553 N  NH1   . ARG A 1 195 ? -0.39071  36.02894 17.36155 1.000 43.32358  ? 193 ARG A NH1   1 
ATOM   1554 N  NH2   . ARG A 1 195 ? 1.08049   35.24497 18.93397 1.000 33.61022  ? 193 ARG A NH2   1 
ATOM   1555 N  N     . ARG A 1 196 ? -5.50320  29.69763 15.29227 1.000 31.70323  ? 194 ARG A N     1 
ATOM   1556 C  CA    . ARG A 1 196 ? -6.81500  29.46229 14.70674 1.000 32.94273  ? 194 ARG A CA    1 
ATOM   1557 C  C     . ARG A 1 196 ? -7.32595  28.05688 14.97675 1.000 32.62941  ? 194 ARG A C     1 
ATOM   1558 O  O     . ARG A 1 196 ? -8.34849  27.65287 14.40490 1.000 36.09141  ? 194 ARG A O     1 
ATOM   1559 C  CB    . ARG A 1 196 ? -6.77257  29.74278 13.20691 1.000 29.55599  ? 194 ARG A CB    1 
ATOM   1560 C  CG    . ARG A 1 196 ? -6.29789  31.16156 12.90864 1.000 35.64738  ? 194 ARG A CG    1 
ATOM   1561 C  CD    . ARG A 1 196 ? -6.41122  31.50910 11.44701 1.000 32.84278  ? 194 ARG A CD    1 
ATOM   1562 N  NE    . ARG A 1 196 ? -5.36990  30.85967 10.66011 1.000 32.72853  ? 194 ARG A NE    1 
ATOM   1563 C  CZ    . ARG A 1 196 ? -5.57574  29.81134 9.87361  1.000 32.42911  ? 194 ARG A CZ    1 
ATOM   1564 N  NH1   . ARG A 1 196 ? -6.76729  29.24933 9.76649  1.000 32.03209  ? 194 ARG A NH1   1 
ATOM   1565 N  NH2   . ARG A 1 196 ? -4.55857  29.31244 9.17768  1.000 33.20245  ? 194 ARG A NH2   1 
ATOM   1566 N  N     . SER A 1 197 ? -6.64692  27.31590 15.84211 1.000 30.24063  ? 195 SER A N     1 
ATOM   1567 C  CA    . SER A 1 197 ? -7.17833  26.05849 16.33455 1.000 30.37368  ? 195 SER A CA    1 
ATOM   1568 C  C     . SER A 1 197 ? -8.28625  26.31674 17.34761 1.000 36.51450  ? 195 SER A C     1 
ATOM   1569 O  O     . SER A 1 197 ? -8.19843  27.22297 18.17762 1.000 32.20061  ? 195 SER A O     1 
ATOM   1570 C  CB    . SER A 1 197 ? -6.06908  25.22900 16.97198 1.000 31.49024  ? 195 SER A CB    1 
ATOM   1571 O  OG    . SER A 1 197 ? -6.59612  24.12098 17.67716 1.000 29.40928  ? 195 SER A OG    1 
ATOM   1572 N  N     . ALA A 1 198 ? -9.34533  25.51682 17.26506 1.000 31.48841  ? 196 ALA A N     1 
ATOM   1573 C  CA    . ALA A 1 198 ? -10.41035 25.60314 18.25272 1.000 36.68111  ? 196 ALA A CA    1 
ATOM   1574 C  C     . ALA A 1 198 ? -9.91248  25.33720 19.67216 1.000 36.93016  ? 196 ALA A C     1 
ATOM   1575 O  O     . ALA A 1 198 ? -10.54778 25.79030 20.63221 1.000 41.95044  ? 196 ALA A O     1 
ATOM   1576 C  CB    . ALA A 1 198 ? -11.52502 24.62615 17.88159 1.000 37.08980  ? 196 ALA A CB    1 
ATOM   1577 N  N     . HIS A 1 199 ? -8.78973  24.63790 19.82889 1.000 33.91422  ? 197 HIS A N     1 
ATOM   1578 C  CA    . HIS A 1 199 ? -8.25076  24.24498 21.12844 1.000 35.21124  ? 197 HIS A CA    1 
ATOM   1579 C  C     . HIS A 1 199 ? -7.13368  25.15036 21.62419 1.000 37.63501  ? 197 HIS A C     1 
ATOM   1580 O  O     . HIS A 1 199 ? -6.53697  24.86142 22.66846 1.000 39.68820  ? 197 HIS A O     1 
ATOM   1581 C  CB    . HIS A 1 199 ? -7.77003  22.79111 21.07049 1.000 37.57727  ? 197 HIS A CB    1 
ATOM   1582 C  CG    . HIS A 1 199 ? -8.60037  21.93121 20.17156 1.000 40.07553  ? 197 HIS A CG    1 
ATOM   1583 N  ND1   . HIS A 1 199 ? -9.92803  21.66413 20.43458 1.000 42.67747  ? 197 HIS A ND1   1 
ATOM   1584 C  CD2   . HIS A 1 199 ? -8.32160  21.33316 18.98621 1.000 36.18509  ? 197 HIS A CD2   1 
ATOM   1585 C  CE1   . HIS A 1 199 ? -10.42439 20.91273 19.46662 1.000 45.66504  ? 197 HIS A CE1   1 
ATOM   1586 N  NE2   . HIS A 1 199 ? -9.47246  20.70217 18.57340 1.000 37.77396  ? 197 HIS A NE2   1 
ATOM   1587 N  N     . HIS A 1 200 ? -6.82838  26.22521 20.90480 1.000 35.83321  ? 198 HIS A N     1 
ATOM   1588 C  CA    . HIS A 1 200 ? -5.84394  27.19074 21.38125 1.000 40.55410  ? 198 HIS A CA    1 
ATOM   1589 C  C     . HIS A 1 200 ? -6.21506  27.76497 22.74341 1.000 36.37023  ? 198 HIS A C     1 
ATOM   1590 O  O     . HIS A 1 200 ? -7.29249  28.33368 22.91566 1.000 38.43391  ? 198 HIS A O     1 
ATOM   1591 C  CB    . HIS A 1 200 ? -5.68984  28.31862 20.36550 1.000 37.86381  ? 198 HIS A CB    1 
ATOM   1592 C  CG    . HIS A 1 200 ? -4.66289  29.33076 20.75663 1.000 39.22374  ? 198 HIS A CG    1 
ATOM   1593 N  ND1   . HIS A 1 200 ? -3.31275  29.06045 20.76053 1.000 37.51281  ? 198 HIS A ND1   1 
ATOM   1594 C  CD2   . HIS A 1 200 ? -4.78836  30.63692 21.09085 1.000 41.19401  ? 198 HIS A CD2   1 
ATOM   1595 C  CE1   . HIS A 1 200 ? -2.65128  30.13999 21.13419 1.000 41.47439  ? 198 HIS A CE1   1 
ATOM   1596 N  NE2   . HIS A 1 200 ? -3.52259  31.11326 21.33310 1.000 46.22669  ? 198 HIS A NE2   1 
ATOM   1597 N  N     . THR A 1 201 ? -5.29557  27.64546 23.69815 1.000 50.42717  ? 199 THR A N     1 
ATOM   1598 C  CA    . THR A 1 201 ? -5.51409  28.10325 25.06188 1.000 48.17262  ? 199 THR A CA    1 
ATOM   1599 C  C     . THR A 1 201 ? -4.19411  28.64210 25.60600 1.000 49.31452  ? 199 THR A C     1 
ATOM   1600 O  O     . THR A 1 201 ? -3.15706  28.58309 24.94076 1.000 57.54583  ? 199 THR A O     1 
ATOM   1601 C  CB    . THR A 1 201 ? -6.04347  26.96861 25.95323 1.000 46.75476  ? 199 THR A CB    1 
ATOM   1602 O  OG1   . THR A 1 201 ? -4.95759  26.12224 26.35016 1.000 55.38745  ? 199 THR A OG1   1 
ATOM   1603 C  CG2   . THR A 1 201 ? -7.08720  26.13479 25.21350 1.000 55.03048  ? 199 THR A CG2   1 
ATOM   1604 N  N     . ARG A 1 202 ? -4.23470  29.16704 26.82627 1.000 52.54990  ? 200 ARG A N     1 
ATOM   1605 C  CA    . ARG A 1 202 ? -3.02177  29.56625 27.52999 1.000 54.31879  ? 200 ARG A CA    1 
ATOM   1606 C  C     . ARG A 1 202 ? -3.14041  29.14791 28.98730 1.000 53.45990  ? 200 ARG A C     1 
ATOM   1607 O  O     . ARG A 1 202 ? -4.24674  28.98570 29.50825 1.000 52.61071  ? 200 ARG A O     1 
ATOM   1608 C  CB    . ARG A 1 202 ? -2.76054  31.08051 27.37816 1.000 57.83010  ? 200 ARG A CB    1 
ATOM   1609 C  CG    . ARG A 1 202 ? -3.91046  31.99613 27.78746 1.000 61.65628  ? 200 ARG A CG    1 
ATOM   1610 C  CD    . ARG A 1 202 ? -4.00869  32.15054 29.30485 1.000 56.90536  ? 200 ARG A CD    1 
ATOM   1611 N  NE    . ARG A 1 202 ? -4.83716  33.29291 29.68825 1.000 63.67403  ? 200 ARG A NE    1 
ATOM   1612 C  CZ    . ARG A 1 202 ? -6.08128  33.20366 30.14215 1.000 59.31927  ? 200 ARG A CZ    1 
ATOM   1613 N  NH1   . ARG A 1 202 ? -6.66643  32.03230 30.32811 1.000 65.78182  ? 200 ARG A NH1   1 
ATOM   1614 N  NH2   . ARG A 1 202 ? -6.74986  34.31692 30.43363 1.000 52.33243  ? 200 ARG A NH2   1 
ATOM   1615 N  N     . GLN A 1 203 ? -1.99352  28.93220 29.63691 1.000 42.61518  ? 201 GLN A N     1 
ATOM   1616 C  CA    . GLN A 1 203 ? -2.01264  28.51847 31.02743 1.000 42.45837  ? 201 GLN A CA    1 
ATOM   1617 C  C     . GLN A 1 203 ? -2.21558  29.71728 31.94441 1.000 43.19649  ? 201 GLN A C     1 
ATOM   1618 O  O     . GLN A 1 203 ? -2.03132  30.87285 31.55156 1.000 47.35713  ? 201 GLN A O     1 
ATOM   1619 C  CB    . GLN A 1 203 ? -0.70807  27.81039 31.41069 1.000 38.42970  ? 201 GLN A CB    1 
ATOM   1620 C  CG    . GLN A 1 203 ? -0.30723  26.72011 30.44141 1.000 39.18617  ? 201 GLN A CG    1 
ATOM   1621 C  CD    . GLN A 1 203 ? 1.15529   26.35216 30.58005 1.000 30.01727  ? 201 GLN A CD    1 
ATOM   1622 O  OE1   . GLN A 1 203 ? 1.68991   26.27408 31.69157 1.000 31.28738  ? 201 GLN A OE1   1 
ATOM   1623 N  NE2   . GLN A 1 203 ? 1.81351   26.13697 29.43044 1.000 34.33098  ? 201 GLN A NE2   1 
ATOM   1624 N  N     . SER A 1 204 ? -2.60006  29.41862 33.18315 1.000 47.62462  ? 202 SER A N     1 
ATOM   1625 C  CA    . SER A 1 204 ? -2.64284  30.42265 34.22722 1.000 47.61818  ? 202 SER A CA    1 
ATOM   1626 C  C     . SER A 1 204 ? -1.23197  30.91586 34.52771 1.000 46.34251  ? 202 SER A C     1 
ATOM   1627 O  O     . SER A 1 204 ? -0.23297  30.27598 34.18537 1.000 45.15435  ? 202 SER A O     1 
ATOM   1628 C  CB    . SER A 1 204 ? -3.30282  29.85878 35.49323 1.000 43.97420  ? 202 SER A CB    1 
ATOM   1629 O  OG    . SER A 1 204 ? -2.56923  28.78821 36.08363 1.000 42.23152  ? 202 SER A OG    1 
ATOM   1630 N  N     . THR A 1 205 ? -1.16308  32.08996 35.14973 1.000 43.70773  ? 203 THR A N     1 
ATOM   1631 C  CA    . THR A 1 205 ? 0.10408   32.63851 35.61119 1.000 46.10322  ? 203 THR A CA    1 
ATOM   1632 C  C     . THR A 1 205 ? 0.88778   31.59213 36.39056 1.000 40.20982  ? 203 THR A C     1 
ATOM   1633 O  O     . THR A 1 205 ? 0.35306   30.94856 37.29786 1.000 41.65458  ? 203 THR A O     1 
ATOM   1634 C  CB    . THR A 1 205 ? -0.15677  33.86451 36.48805 1.000 42.74484  ? 203 THR A CB    1 
ATOM   1635 O  OG1   . THR A 1 205 ? -0.87730  34.83633 35.72270 1.000 49.98466  ? 203 THR A OG1   1 
ATOM   1636 C  CG2   . THR A 1 205 ? 1.14528   34.47202 36.95279 1.000 42.94575  ? 203 THR A CG2   1 
ATOM   1637 N  N     . PHE A 1 206 ? 2.16346   31.42073 36.02967 1.000 36.41559  ? 204 PHE A N     1 
ATOM   1638 C  CA    . PHE A 1 206 ? 2.99894   30.44402 36.72159 1.000 33.57566  ? 204 PHE A CA    1 
ATOM   1639 C  C     . PHE A 1 206 ? 3.42498   30.94775 38.09603 1.000 29.78638  ? 204 PHE A C     1 
ATOM   1640 O  O     . PHE A 1 206 ? 3.44891   30.17513 39.05834 1.000 28.60270  ? 204 PHE A O     1 
ATOM   1641 C  CB    . PHE A 1 206 ? 4.22931   30.11358 35.87237 1.000 33.39685  ? 204 PHE A CB    1 
ATOM   1642 C  CG    . PHE A 1 206 ? 5.11343   29.04845 36.45937 1.000 28.15556  ? 204 PHE A CG    1 
ATOM   1643 C  CD1   . PHE A 1 206 ? 4.60961   27.80782 36.79973 1.000 25.46269  ? 204 PHE A CD1   1 
ATOM   1644 C  CD2   . PHE A 1 206 ? 6.47038   29.28392 36.63249 1.000 34.34833  ? 204 PHE A CD2   1 
ATOM   1645 C  CE1   . PHE A 1 206 ? 5.42472   26.81858 37.32556 1.000 30.94631  ? 204 PHE A CE1   1 
ATOM   1646 C  CE2   . PHE A 1 206 ? 7.29929   28.30228 37.15168 1.000 32.82530  ? 204 PHE A CE2   1 
ATOM   1647 C  CZ    . PHE A 1 206 ? 6.78282   27.06918 37.50246 1.000 29.93902  ? 204 PHE A CZ    1 
ATOM   1648 N  N     . GLU A 1 207 ? 3.77438   32.22829 38.20023 1.000 36.86455  ? 205 GLU A N     1 
ATOM   1649 C  CA    . GLU A 1 207 ? 4.16561   32.79468 39.48789 1.000 37.44109  ? 205 GLU A CA    1 
ATOM   1650 C  C     . GLU A 1 207 ? 3.04802   32.65294 40.50841 1.000 37.67505  ? 205 GLU A C     1 
ATOM   1651 O  O     . GLU A 1 207 ? 1.91466   33.08146 40.26864 1.000 34.60626  ? 205 GLU A O     1 
ATOM   1652 C  CB    . GLU A 1 207 ? 4.53327   34.26608 39.31689 1.000 42.40462  ? 205 GLU A CB    1 
ATOM   1653 C  CG    . GLU A 1 207 ? 5.98276   34.47192 38.98454 1.000 54.74160  ? 205 GLU A CG    1 
ATOM   1654 C  CD    . GLU A 1 207 ? 6.86571   34.08896 40.14866 1.000 57.22993  ? 205 GLU A CD    1 
ATOM   1655 O  OE1   . GLU A 1 207 ? 7.80198   33.28599 39.94738 1.000 62.94623  ? 205 GLU A OE1   1 
ATOM   1656 O  OE2   . GLU A 1 207 ? 6.62949   34.60298 41.26556 1.000 60.33854  ? 205 GLU A OE2   1 
ATOM   1657 N  N     . GLY A 1 208 ? 3.37665   32.05716 41.65789 1.000 34.47027  ? 206 GLY A N     1 
ATOM   1658 C  CA    . GLY A 1 208 ? 2.40423   31.85336 42.70514 1.000 35.24384  ? 206 GLY A CA    1 
ATOM   1659 C  C     . GLY A 1 208 ? 1.42960   30.73427 42.45142 1.000 35.38879  ? 206 GLY A C     1 
ATOM   1660 O  O     . GLY A 1 208 ? 0.46257   30.59181 43.20753 1.000 32.69577  ? 206 GLY A O     1 
ATOM   1661 N  N     . SER A 1 209 ? 1.65010   29.92810 41.42057 1.000 29.92161  ? 207 SER A N     1 
ATOM   1662 C  CA    . SER A 1 209 ? 0.66730   28.93485 41.01818 1.000 30.59577  ? 207 SER A CA    1 
ATOM   1663 C  C     . SER A 1 209 ? 0.82169   27.65140 41.82466 1.000 27.39707  ? 207 SER A C     1 
ATOM   1664 O  O     . SER A 1 209 ? 1.86122   27.38889 42.43577 1.000 27.28966  ? 207 SER A O     1 
ATOM   1665 C  CB    . SER A 1 209 ? 0.80249   28.61786 39.53226 1.000 29.89979  ? 207 SER A CB    1 
ATOM   1666 O  OG    . SER A 1 209 ? 2.01400   27.91273 39.29461 1.000 27.71252  ? 207 SER A OG    1 
ATOM   1667 N  N     . ARG A 1 210 ? -0.22727  26.82452 41.77821 1.000 26.15770  ? 208 ARG A N     1 
ATOM   1668 C  CA    . ARG A 1 210 ? -0.14867  25.50858 42.40184 1.000 24.53916  ? 208 ARG A CA    1 
ATOM   1669 C  C     . ARG A 1 210 ? 0.94442   24.65828 41.76674 1.000 27.55034  ? 208 ARG A C     1 
ATOM   1670 O  O     . ARG A 1 210 ? 1.67538   23.95306 42.47204 1.000 26.03490  ? 208 ARG A O     1 
ATOM   1671 C  CB    . ARG A 1 210 ? -1.50003  24.79939 42.30738 1.000 27.23991  ? 208 ARG A CB    1 
ATOM   1672 C  CG    . ARG A 1 210 ? -1.56201  23.45709 43.03610 1.000 27.73725  ? 208 ARG A CG    1 
ATOM   1673 C  CD    . ARG A 1 210 ? -2.87406  22.74567 42.72498 1.000 28.64254  ? 208 ARG A CD    1 
ATOM   1674 N  NE    . ARG A 1 210 ? -3.03949  21.52063 43.49833 1.000 24.14746  ? 208 ARG A NE    1 
ATOM   1675 C  CZ    . ARG A 1 210 ? -3.56639  21.47877 44.71977 1.000 28.71245  ? 208 ARG A CZ    1 
ATOM   1676 N  NH1   . ARG A 1 210 ? -3.98318  22.57454 45.33425 1.000 31.46076  ? 208 ARG A NH1   1 
ATOM   1677 N  NH2   . ARG A 1 210 ? -3.68675  20.30701 45.33294 1.000 28.66788  ? 208 ARG A NH2   1 
ATOM   1678 N  N     . ARG A 1 211 ? 1.07681   24.71185 40.43905 1.000 23.92706  ? 209 ARG A N     1 
ATOM   1679 C  CA    . ARG A 1 211 ? 2.05967   23.84091 39.80489 1.000 25.15676  ? 209 ARG A CA    1 
ATOM   1680 C  C     . ARG A 1 211 ? 3.48636   24.30838 40.07088 1.000 26.88161  ? 209 ARG A C     1 
ATOM   1681 O  O     . ARG A 1 211 ? 4.41227   23.49244 40.05033 1.000 24.87237  ? 209 ARG A O     1 
ATOM   1682 C  CB    . ARG A 1 211 ? 1.77236   23.72544 38.30729 1.000 25.82266  ? 209 ARG A CB    1 
ATOM   1683 C  CG    . ARG A 1 211 ? 2.07999   24.96398 37.46870 1.000 23.80350  ? 209 ARG A CG    1 
ATOM   1684 C  CD    . ARG A 1 211 ? 1.47808   24.76843 36.06369 1.000 22.02979  ? 209 ARG A CD    1 
ATOM   1685 N  NE    . ARG A 1 211 ? 1.71298   25.87177 35.13305 1.000 26.68316  ? 209 ARG A NE    1 
ATOM   1686 C  CZ    . ARG A 1 211 ? 1.06460   27.02867 35.16602 1.000 30.02157  ? 209 ARG A CZ    1 
ATOM   1687 N  NH1   . ARG A 1 211 ? 0.16149   27.29159 36.10246 1.000 28.71447  ? 209 ARG A NH1   1 
ATOM   1688 N  NH2   . ARG A 1 211 ? 1.34734   27.95438 34.26522 1.000 31.56925  ? 209 ARG A NH2   1 
ATOM   1689 N  N     . GLN A 1 212 ? 3.70093   25.60755 40.28312 1.000 25.99732  ? 210 GLN A N     1 
ATOM   1690 C  CA    . GLN A 1 212 ? 5.02186   26.04421 40.72563 1.000 26.42460  ? 210 GLN A CA    1 
ATOM   1691 C  C     . GLN A 1 212 ? 5.36174   25.40463 42.06792 1.000 26.98590  ? 210 GLN A C     1 
ATOM   1692 O  O     . GLN A 1 212 ? 6.48692   24.93680 42.28156 1.000 26.44489  ? 210 GLN A O     1 
ATOM   1693 C  CB    . GLN A 1 212 ? 5.06532   27.56792 40.81455 1.000 28.21910  ? 210 GLN A CB    1 
ATOM   1694 C  CG    . GLN A 1 212 ? 6.41240   28.14664 41.24791 1.000 31.44419  ? 210 GLN A CG    1 
ATOM   1695 C  CD    . GLN A 1 212 ? 6.39687   29.65969 41.31291 1.000 37.93194  ? 210 GLN A CD    1 
ATOM   1696 O  OE1   . GLN A 1 212 ? 5.53219   30.25722 41.96528 1.000 31.69649  ? 210 GLN A OE1   1 
ATOM   1697 N  NE2   . GLN A 1 212 ? 7.33892   30.29055 40.62657 1.000 35.84793  ? 210 GLN A NE2   1 
ATOM   1698 N  N     . LYS A 1 213 ? 4.38605   25.33827 42.97397 1.000 23.30046  ? 211 LYS A N     1 
ATOM   1699 C  CA    . LYS A 1 213 ? 4.65191   24.71714 44.26797 1.000 24.52613  ? 211 LYS A CA    1 
ATOM   1700 C  C     . LYS A 1 213 ? 4.81503   23.21045 44.13393 1.000 26.07678  ? 211 LYS A C     1 
ATOM   1701 O  O     . LYS A 1 213 ? 5.63607   22.60766 44.84470 1.000 24.96797  ? 211 LYS A O     1 
ATOM   1702 C  CB    . LYS A 1 213 ? 3.52909   25.04371 45.25581 1.000 25.18008  ? 211 LYS A CB    1 
ATOM   1703 C  CG    . LYS A 1 213 ? 3.42775   26.51715 45.59443 1.000 28.21787  ? 211 LYS A CG    1 
ATOM   1704 C  CD    . LYS A 1 213 ? 2.14125   26.80661 46.39491 1.000 26.45148  ? 211 LYS A CD    1 
ATOM   1705 C  CE    . LYS A 1 213 ? 1.97560   28.28110 46.65616 1.000 30.15703  ? 211 LYS A CE    1 
ATOM   1706 N  NZ    . LYS A 1 213 ? 1.54715   28.95795 45.38870 1.000 30.78555  ? 211 LYS A NZ    1 
ATOM   1707 N  N     . ARG A 1 214 ? 4.03258   22.57988 43.24964 1.000 25.15017  ? 212 ARG A N     1 
ATOM   1708 C  CA    . ARG A 1 214 ? 4.21741   21.15198 42.99563 1.000 22.59601  ? 212 ARG A CA    1 
ATOM   1709 C  C     . ARG A 1 214 ? 5.67307   20.85145 42.66786 1.000 25.46234  ? 212 ARG A C     1 
ATOM   1710 O  O     . ARG A 1 214 ? 6.27844   19.94677 43.25243 1.000 25.45334  ? 212 ARG A O     1 
ATOM   1711 C  CB    . ARG A 1 214 ? 3.31336   20.67483 41.84606 1.000 22.00391  ? 212 ARG A CB    1 
ATOM   1712 C  CG    . ARG A 1 214 ? 1.83485   20.50885 42.24312 1.000 21.93390  ? 212 ARG A CG    1 
ATOM   1713 C  CD    . ARG A 1 214 ? 0.98342   20.26856 40.97612 1.000 23.85560  ? 212 ARG A CD    1 
ATOM   1714 N  NE    . ARG A 1 214 ? 1.51694   19.17314 40.17633 1.000 25.03230  ? 212 ARG A NE    1 
ATOM   1715 C  CZ    . ARG A 1 214 ? 1.12233   17.91176 40.28609 1.000 24.69046  ? 212 ARG A CZ    1 
ATOM   1716 N  NH1   . ARG A 1 214 ? 0.16487   17.55931 41.13221 1.000 25.60968  ? 212 ARG A NH1   1 
ATOM   1717 N  NH2   . ARG A 1 214 ? 1.69189   16.98163 39.52138 1.000 26.08585  ? 212 ARG A NH2   1 
ATOM   1718 N  N     . ALA A 1 215 ? 6.23968   21.59689 41.71381 1.000 24.70710  ? 213 ALA A N     1 
ATOM   1719 C  CA    . ALA A 1 215 ? 7.57735   21.28792 41.22300 1.000 22.99207  ? 213 ALA A CA    1 
ATOM   1720 C  C     . ALA A 1 215 ? 8.61213   21.55377 42.30743 1.000 28.94719  ? 213 ALA A C     1 
ATOM   1721 O  O     . ALA A 1 215 ? 9.58091   20.79860 42.45313 1.000 28.65348  ? 213 ALA A O     1 
ATOM   1722 C  CB    . ALA A 1 215 ? 7.87254   22.09619 39.95827 1.000 24.94207  ? 213 ALA A CB    1 
ATOM   1723 N  N     A GLU A 1 216 ? 8.43077   22.63015 43.07271 0.520 26.67454  ? 214 GLU A N     1 
ATOM   1724 N  N     B GLU A 1 216 ? 8.40921   22.60554 43.10101 0.480 26.70407  ? 214 GLU A N     1 
ATOM   1725 C  CA    A GLU A 1 216 ? 9.35190   22.91460 44.17280 0.520 29.58696  ? 214 GLU A CA    1 
ATOM   1726 C  CA    B GLU A 1 216 ? 9.37105   22.90943 44.15891 0.480 29.60734  ? 214 GLU A CA    1 
ATOM   1727 C  C     A GLU A 1 216 ? 9.33477   21.80586 45.21256 0.520 28.79311  ? 214 GLU A C     1 
ATOM   1728 C  C     B GLU A 1 216 ? 9.32988   21.86979 45.27296 0.480 28.85792  ? 214 GLU A C     1 
ATOM   1729 O  O     A GLU A 1 216 ? 10.39127  21.37059 45.69233 0.520 30.05453  ? 214 GLU A O     1 
ATOM   1730 O  O     B GLU A 1 216 ? 10.37053  21.54411 45.86148 0.480 29.96198  ? 214 GLU A O     1 
ATOM   1731 C  CB    A GLU A 1 216 ? 9.00574   24.25669 44.81289 0.520 30.16501  ? 214 GLU A CB    1 
ATOM   1732 C  CB    B GLU A 1 216 ? 9.11461   24.30584 44.71811 0.480 30.45103  ? 214 GLU A CB    1 
ATOM   1733 C  CG    A GLU A 1 216 ? 8.82705   25.35932 43.79434 0.520 34.44262  ? 214 GLU A CG    1 
ATOM   1734 C  CG    B GLU A 1 216 ? 10.24590  25.29912 44.42193 0.480 41.10753  ? 214 GLU A CG    1 
ATOM   1735 C  CD    A GLU A 1 216 ? 8.28338   26.63439 44.38858 0.520 37.02406  ? 214 GLU A CD    1 
ATOM   1736 C  CD    B GLU A 1 216 ? 11.63626  24.73976 44.72023 0.480 35.04712  ? 214 GLU A CD    1 
ATOM   1737 O  OE1   A GLU A 1 216 ? 7.90406   26.63996 45.57776 0.520 33.92960  ? 214 GLU A OE1   1 
ATOM   1738 O  OE1   B GLU A 1 216 ? 12.02197  24.69046 45.91062 0.480 45.45292  ? 214 GLU A OE1   1 
ATOM   1739 O  OE2   A GLU A 1 216 ? 8.20524   27.63412 43.65083 0.520 39.54986  ? 214 GLU A OE2   1 
ATOM   1740 O  OE2   B GLU A 1 216 ? 12.34777  24.36657 43.75892 0.480 38.46041  ? 214 GLU A OE2   1 
ATOM   1741 N  N     . LEU A 1 217 ? 8.13957   21.35740 45.60287 1.000 26.12712  ? 215 LEU A N     1 
ATOM   1742 C  CA    . LEU A 1 217 ? 8.04593   20.33721 46.63804 1.000 24.88157  ? 215 LEU A CA    1 
ATOM   1743 C  C     . LEU A 1 217 ? 8.76365   19.06353 46.21883 1.000 29.08296  ? 215 LEU A C     1 
ATOM   1744 O  O     . LEU A 1 217 ? 9.44189   18.42010 47.03325 1.000 27.74461  ? 215 LEU A O     1 
ATOM   1745 C  CB    . LEU A 1 217 ? 6.57754   20.05384 46.96055 1.000 25.14335  ? 215 LEU A CB    1 
ATOM   1746 C  CG    . LEU A 1 217 ? 5.94587   21.12525 47.84079 1.000 25.07113  ? 215 LEU A CG    1 
ATOM   1747 C  CD1   . LEU A 1 217 ? 4.42285   21.00530 47.76097 1.000 27.12060  ? 215 LEU A CD1   1 
ATOM   1748 C  CD2   . LEU A 1 217 ? 6.43705   20.99871 49.29431 1.000 26.18150  ? 215 LEU A CD2   1 
ATOM   1749 N  N     . VAL A 1 218 ? 8.63752   18.68449 44.95130 1.000 27.29465  ? 216 VAL A N     1 
ATOM   1750 C  CA    . VAL A 1 218 ? 9.32682   17.48809 44.50617 1.000 28.01413  ? 216 VAL A CA    1 
ATOM   1751 C  C     . VAL A 1 218 ? 10.83314  17.69622 44.55850 1.000 29.94996  ? 216 VAL A C     1 
ATOM   1752 O  O     . VAL A 1 218 ? 11.57418  16.80523 44.98006 1.000 29.00105  ? 216 VAL A O     1 
ATOM   1753 C  CB    . VAL A 1 218 ? 8.85704   17.08398 43.10291 1.000 26.69991  ? 216 VAL A CB    1 
ATOM   1754 C  CG1   . VAL A 1 218 ? 9.69175   15.92194 42.60372 1.000 28.19834  ? 216 VAL A CG1   1 
ATOM   1755 C  CG2   . VAL A 1 218 ? 7.38126   16.70092 43.15453 1.000 28.58045  ? 216 VAL A CG2   1 
ATOM   1756 N  N     . ARG A 1 219 ? 11.31473  18.86817 44.13764 1.000 28.03712  ? 217 ARG A N     1 
ATOM   1757 C  CA    . ARG A 1 219 ? 12.75590  19.11608 44.21294 1.000 28.19871  ? 217 ARG A CA    1 
ATOM   1758 C  C     . ARG A 1 219 ? 13.24833  19.09070 45.65037 1.000 30.42865  ? 217 ARG A C     1 
ATOM   1759 O  O     . ARG A 1 219 ? 14.33550  18.57985 45.92704 1.000 32.03917  ? 217 ARG A O     1 
ATOM   1760 C  CB    . ARG A 1 219 ? 13.09981  20.44667 43.56215 1.000 30.37548  ? 217 ARG A CB    1 
ATOM   1761 C  CG    . ARG A 1 219 ? 13.20841  20.30864 42.04630 1.000 34.77467  ? 217 ARG A CG    1 
ATOM   1762 C  CD    . ARG A 1 219 ? 13.83124  21.53582 41.43296 1.000 37.05184  ? 217 ARG A CD    1 
ATOM   1763 N  NE    . ARG A 1 219 ? 12.83331  22.58488 41.29664 1.000 42.57945  ? 217 ARG A NE    1 
ATOM   1764 C  CZ    . ARG A 1 219 ? 11.92891  22.63504 40.32478 1.000 36.69265  ? 217 ARG A CZ    1 
ATOM   1765 N  NH1   . ARG A 1 219 ? 11.86626  21.70228 39.38435 1.000 34.56420  ? 217 ARG A NH1   1 
ATOM   1766 N  NH2   . ARG A 1 219 ? 11.06876  23.64535 40.29651 1.000 34.47034  ? 217 ARG A NH2   1 
ATOM   1767 N  N     . LEU A 1 220 ? 12.46122  19.63654 46.58185 1.000 28.23873  ? 218 LEU A N     1 
ATOM   1768 C  CA    . LEU A 1 220 ? 12.90261  19.66697 47.97213 1.000 31.10414  ? 218 LEU A CA    1 
ATOM   1769 C  C     . LEU A 1 220 ? 13.02762  18.26122 48.54297 1.000 30.83091  ? 218 LEU A C     1 
ATOM   1770 O  O     . LEU A 1 220 ? 13.94949  17.97785 49.32002 1.000 34.57785  ? 218 LEU A O     1 
ATOM   1771 C  CB    . LEU A 1 220 ? 11.93853  20.50029 48.81770 1.000 30.45812  ? 218 LEU A CB    1 
ATOM   1772 C  CG    . LEU A 1 220 ? 11.97113  22.01150 48.58238 1.000 33.02346  ? 218 LEU A CG    1 
ATOM   1773 C  CD1   . LEU A 1 220 ? 10.76176  22.67185 49.24513 1.000 30.63494  ? 218 LEU A CD1   1 
ATOM   1774 C  CD2   . LEU A 1 220 ? 13.27673  22.59510 49.11083 1.000 32.03909  ? 218 LEU A CD2   1 
ATOM   1775 N  N     . VAL A 1 221 ? 12.09953  17.37254 48.18679 1.000 30.80188  ? 219 VAL A N     1 
ATOM   1776 C  CA    . VAL A 1 221 ? 12.16836  16.00635 48.68942 1.000 30.31851  ? 219 VAL A CA    1 
ATOM   1777 C  C     . VAL A 1 221 ? 13.29591  15.24436 48.00248 1.000 32.32288  ? 219 VAL A C     1 
ATOM   1778 O  O     . VAL A 1 221 ? 14.01941  14.47213 48.64643 1.000 34.66431  ? 219 VAL A O     1 
ATOM   1779 C  CB    . VAL A 1 221 ? 10.81014  15.30290 48.51594 1.000 30.09744  ? 219 VAL A CB    1 
ATOM   1780 C  CG1   . VAL A 1 221 ? 10.93306  13.81907 48.82268 1.000 34.06113  ? 219 VAL A CG1   1 
ATOM   1781 C  CG2   . VAL A 1 221 ? 9.74531   15.95235 49.40354 1.000 31.75320  ? 219 VAL A CG2   1 
ATOM   1782 N  N     . LEU A 1 222 ? 13.46953  15.44309 46.68923 1.000 30.65768  ? 220 LEU A N     1 
ATOM   1783 C  CA    . LEU A 1 222 ? 14.59514  14.80679 46.00777 1.000 33.51226  ? 220 LEU A CA    1 
ATOM   1784 C  C     . LEU A 1 222 ? 15.92195  15.20509 46.62976 1.000 36.11193  ? 220 LEU A C     1 
ATOM   1785 O  O     . LEU A 1 222 ? 16.82774  14.37378 46.75628 1.000 39.12315  ? 220 LEU A O     1 
ATOM   1786 C  CB    . LEU A 1 222 ? 14.62177  15.14312 44.51400 1.000 34.78284  ? 220 LEU A CB    1 
ATOM   1787 C  CG    . LEU A 1 222 ? 13.67544  14.35191 43.63438 1.000 36.32287  ? 220 LEU A CG    1 
ATOM   1788 C  CD1   . LEU A 1 222 ? 13.30335  15.16164 42.37766 1.000 40.65442  ? 220 LEU A CD1   1 
ATOM   1789 C  CD2   . LEU A 1 222 ? 14.34874  13.02073 43.31634 1.000 34.55767  ? 220 LEU A CD2   1 
ATOM   1790 N  N     . ALA A 1 223 ? 16.05759  16.47553 47.01915 1.000 38.74976  ? 221 ALA A N     1 
ATOM   1791 C  CA    . ALA A 1 223 ? 17.30700  16.96720 47.59005 1.000 39.34900  ? 221 ALA A CA    1 
ATOM   1792 C  C     . ALA A 1 223 ? 17.55708  16.47161 49.00927 1.000 44.28644  ? 221 ALA A C     1 
ATOM   1793 O  O     . ALA A 1 223 ? 18.70539  16.51852 49.47460 1.000 44.98554  ? 221 ALA A O     1 
ATOM   1794 C  CB    . ALA A 1 223 ? 17.31510  18.49545 47.58154 1.000 37.97922  ? 221 ALA A CB    1 
ATOM   1795 N  N     . GLU A 1 224 ? 16.52662  15.99835 49.70697 1.000 41.49326  ? 222 GLU A N     1 
ATOM   1796 C  CA    . GLU A 1 224 ? 16.61790  15.69448 51.13744 1.000 42.27559  ? 222 GLU A CA    1 
ATOM   1797 C  C     . GLU A 1 224 ? 15.79774  14.45542 51.47266 1.000 40.69844  ? 222 GLU A C     1 
ATOM   1798 O  O     . GLU A 1 224 ? 14.74888  14.54043 52.12096 1.000 38.72067  ? 222 GLU A O     1 
ATOM   1799 C  CB    . GLU A 1 224 ? 16.14915  16.89044 51.97000 1.000 39.39029  ? 222 GLU A CB    1 
ATOM   1800 C  CG    . GLU A 1 224 ? 16.74253  16.94309 53.36598 1.000 44.99986  ? 222 GLU A CG    1 
ATOM   1801 C  CD    . GLU A 1 224 ? 16.38031  18.21233 54.11467 1.000 48.71252  ? 222 GLU A CD    1 
ATOM   1802 O  OE1   . GLU A 1 224 ? 15.97975  19.20580 53.46518 1.000 46.89671  ? 222 GLU A OE1   1 
ATOM   1803 O  OE2   . GLU A 1 224 ? 16.54587  18.22987 55.35307 1.000 52.45070  ? 222 GLU A OE2   1 
ATOM   1804 N  N     . PRO A 1 225 ? 16.27044  13.27499 51.07820 1.000 42.32634  ? 223 PRO A N     1 
ATOM   1805 C  CA    . PRO A 1 225 ? 15.57786  12.04014 51.46935 1.000 42.89219  ? 223 PRO A CA    1 
ATOM   1806 C  C     . PRO A 1 225 ? 15.38988  11.99054 52.98076 1.000 44.83344  ? 223 PRO A C     1 
ATOM   1807 O  O     . PRO A 1 225 ? 16.31457  12.27041 53.74945 1.000 50.08744  ? 223 PRO A O     1 
ATOM   1808 C  CB    . PRO A 1 225 ? 16.52389  10.93117 50.98994 1.000 45.61898  ? 223 PRO A CB    1 
ATOM   1809 C  CG    . PRO A 1 225 ? 17.44025  11.57412 50.01573 1.000 51.93937  ? 223 PRO A CG    1 
ATOM   1810 C  CD    . PRO A 1 225 ? 17.55936  13.00768 50.41915 1.000 48.84157  ? 223 PRO A CD    1 
ATOM   1811 N  N     . GLY A 1 226 ? 14.18191  11.62911 53.40998 1.000 45.76109  ? 224 GLY A N     1 
ATOM   1812 C  CA    . GLY A 1 226 ? 13.86182  11.55919 54.82078 1.000 48.97523  ? 224 GLY A CA    1 
ATOM   1813 C  C     . GLY A 1 226 ? 13.36910  12.85070 55.43358 1.000 46.64859  ? 224 GLY A C     1 
ATOM   1814 O  O     . GLY A 1 226 ? 13.10779  12.87997 56.64214 1.000 47.13460  ? 224 GLY A O     1 
ATOM   1815 N  N     . ILE A 1 227 ? 13.22466  13.91596 54.64057 1.000 42.54474  ? 225 ILE A N     1 
ATOM   1816 C  CA    . ILE A 1 227 ? 12.78815  15.20051 55.17453 1.000 45.87608  ? 225 ILE A CA    1 
ATOM   1817 C  C     . ILE A 1 227 ? 11.45859  15.02885 55.89475 1.000 36.52631  ? 225 ILE A C     1 
ATOM   1818 O  O     . ILE A 1 227 ? 10.53914  14.38116 55.38539 1.000 42.20960  ? 225 ILE A O     1 
ATOM   1819 C  CB    . ILE A 1 227 ? 12.69151  16.24203 54.04193 1.000 43.20642  ? 225 ILE A CB    1 
ATOM   1820 C  CG1   . ILE A 1 227 ? 12.42501  17.63371 54.62719 1.000 41.39074  ? 225 ILE A CG1   1 
ATOM   1821 C  CG2   . ILE A 1 227 ? 11.61803  15.84483 53.02854 1.000 38.73224  ? 225 ILE A CG2   1 
ATOM   1822 C  CD1   . ILE A 1 227 ? 12.49806  18.75713 53.63737 1.000 38.93132  ? 225 ILE A CD1   1 
ATOM   1823 N  N     . GLY A 1 228 ? 11.35160  15.60906 57.09258 1.000 41.19651  ? 226 GLY A N     1 
ATOM   1824 C  CA    . GLY A 1 228 ? 10.10984  15.54251 57.82728 1.000 45.10908  ? 226 GLY A CA    1 
ATOM   1825 C  C     . GLY A 1 228 ? 9.01989   16.38859 57.19858 1.000 38.55715  ? 226 GLY A C     1 
ATOM   1826 O  O     . GLY A 1 228 ? 9.26946   17.36074 56.48384 1.000 38.25196  ? 226 GLY A O     1 
ATOM   1827 N  N     . ILE A 1 229 ? 7.77133   16.01129 57.47879 1.000 41.61344  ? 227 ILE A N     1 
ATOM   1828 C  CA    . ILE A 1 229 ? 6.65320   16.69309 56.83804 1.000 43.17086  ? 227 ILE A CA    1 
ATOM   1829 C  C     . ILE A 1 229 ? 6.64446   18.17666 57.20263 1.000 38.20295  ? 227 ILE A C     1 
ATOM   1830 O  O     . ILE A 1 229 ? 6.41935   19.03625 56.33798 1.000 38.18636  ? 227 ILE A O     1 
ATOM   1831 C  CB    . ILE A 1 229 ? 5.31642   16.01487 57.19299 1.000 48.66384  ? 227 ILE A CB    1 
ATOM   1832 C  CG1   . ILE A 1 229 ? 4.15714   16.85268 56.63962 1.000 52.11890  ? 227 ILE A CG1   1 
ATOM   1833 C  CG2   . ILE A 1 229 ? 5.16884   15.84846 58.71257 1.000 49.21886  ? 227 ILE A CG2   1 
ATOM   1834 C  CD1   . ILE A 1 229 ? 2.82435   16.11318 56.56265 1.000 57.36173  ? 227 ILE A CD1   1 
ATOM   1835 N  N     . ASP A 1 230 ? 6.88980   18.50741 58.47591 1.000 39.88536  ? 228 ASP A N     1 
ATOM   1836 C  CA    . ASP A 1 230 ? 6.87987   19.91695 58.86163 1.000 40.06297  ? 228 ASP A CA    1 
ATOM   1837 C  C     . ASP A 1 230 ? 8.08482   20.65612 58.28120 1.000 40.58774  ? 228 ASP A C     1 
ATOM   1838 O  O     . ASP A 1 230 ? 7.95531   21.79183 57.80767 1.000 41.05306  ? 228 ASP A O     1 
ATOM   1839 C  CB    . ASP A 1 230 ? 6.81491   20.06862 60.38548 1.000 45.61575  ? 228 ASP A CB    1 
ATOM   1840 C  CG    . ASP A 1 230 ? 7.74077   19.11142 61.12844 1.000 41.81340  ? 228 ASP A CG    1 
ATOM   1841 O  OD1   . ASP A 1 230 ? 8.44376   18.32221 60.46508 1.000 50.46400  ? 228 ASP A OD1   1 
ATOM   1842 O  OD2   . ASP A 1 230 ? 7.76593   19.15778 62.37841 1.000 47.36816  ? 228 ASP A OD2   1 
ATOM   1843 N  N     . GLU A 1 231 ? 9.25825   20.02010 58.28411 1.000 38.14663  ? 229 GLU A N     1 
ATOM   1844 C  CA    . GLU A 1 231 ? 10.42494  20.61385 57.63016 1.000 40.55797  ? 229 GLU A CA    1 
ATOM   1845 C  C     . GLU A 1 231 ? 10.17058  20.90718 56.15593 1.000 41.89867  ? 229 GLU A C     1 
ATOM   1846 O  O     . GLU A 1 231 ? 10.64255  21.91997 55.62133 1.000 36.86996  ? 229 GLU A O     1 
ATOM   1847 C  CB    . GLU A 1 231 ? 11.63174  19.69302 57.77897 1.000 39.85004  ? 229 GLU A CB    1 
ATOM   1848 C  CG    . GLU A 1 231 ? 12.88309  20.24403 57.15579 1.000 45.55978  ? 229 GLU A CG    1 
ATOM   1849 C  CD    . GLU A 1 231 ? 14.07402  19.35886 57.41618 1.000 55.18856  ? 229 GLU A CD    1 
ATOM   1850 O  OE1   . GLU A 1 231 ? 13.97446  18.45963 58.28850 1.000 57.75923  ? 229 GLU A OE1   1 
ATOM   1851 O  OE2   . GLU A 1 231 ? 15.09611  19.55601 56.72929 1.000 59.95437  ? 229 GLU A OE2   1 
ATOM   1852 N  N     . LEU A 1 232 ? 9.45906   20.02076 55.46662 1.000 32.90858  ? 230 LEU A N     1 
ATOM   1853 C  CA    . LEU A 1 232 ? 9.14722   20.29102 54.06929 1.000 34.15137  ? 230 LEU A CA    1 
ATOM   1854 C  C     . LEU A 1 232 ? 8.31175   21.56173 53.93053 1.000 30.07161  ? 230 LEU A C     1 
ATOM   1855 O  O     . LEU A 1 232 ? 8.55562   22.38677 53.04052 1.000 30.44250  ? 230 LEU A O     1 
ATOM   1856 C  CB    . LEU A 1 232 ? 8.43685   19.08596 53.45949 1.000 31.31804  ? 230 LEU A CB    1 
ATOM   1857 C  CG    . LEU A 1 232 ? 8.04186   19.17377 51.98493 1.000 31.75731  ? 230 LEU A CG    1 
ATOM   1858 C  CD1   . LEU A 1 232 ? 9.27948   19.38435 51.10274 1.000 30.60407  ? 230 LEU A CD1   1 
ATOM   1859 C  CD2   . LEU A 1 232 ? 7.30211   17.90186 51.61342 1.000 34.03224  ? 230 LEU A CD2   1 
ATOM   1860 N  N     . ALA A 1 233 ? 7.33889   21.75449 54.82123 1.000 32.55369  ? 231 ALA A N     1 
ATOM   1861 C  CA    . ALA A 1 233 ? 6.54110   22.97601 54.77787 1.000 34.85136  ? 231 ALA A CA    1 
ATOM   1862 C  C     . ALA A 1 233 ? 7.39671   24.20570 55.05561 1.000 33.19867  ? 231 ALA A C     1 
ATOM   1863 O  O     . ALA A 1 233 ? 7.22903   25.24967 54.41192 1.000 38.10020  ? 231 ALA A O     1 
ATOM   1864 C  CB    . ALA A 1 233 ? 5.39722   22.88447 55.78660 1.000 33.73153  ? 231 ALA A CB    1 
ATOM   1865 N  N     . GLU A 1 234 ? 8.31159   24.10074 56.01746 1.000 35.67276  ? 232 GLU A N     1 
ATOM   1866 C  CA    . GLU A 1 234 ? 9.20052   25.21238 56.33513 1.000 37.54502  ? 232 GLU A CA    1 
ATOM   1867 C  C     . GLU A 1 234 ? 10.04955  25.58019 55.12688 1.000 38.70373  ? 232 GLU A C     1 
ATOM   1868 O  O     . GLU A 1 234 ? 10.22216  26.76486 54.81117 1.000 38.92664  ? 232 GLU A O     1 
ATOM   1869 C  CB    . GLU A 1 234 ? 10.08064  24.83552 57.52765 1.000 42.05695  ? 232 GLU A CB    1 
ATOM   1870 C  CG    . GLU A 1 234 ? 9.34036   24.90054 58.84166 1.000 43.55635  ? 232 GLU A CG    1 
ATOM   1871 C  CD    . GLU A 1 234 ? 10.26630  24.84477 60.03889 1.000 57.90449  ? 232 GLU A CD    1 
ATOM   1872 O  OE1   . GLU A 1 234 ? 11.47744  24.61286 59.83354 1.000 62.63972  ? 232 GLU A OE1   1 
ATOM   1873 O  OE2   . GLU A 1 234 ? 9.78570   25.02568 61.18083 1.000 62.35146  ? 232 GLU A OE2   1 
ATOM   1874 N  N     . ARG A 1 235 ? 10.56556  24.57259 54.42478 1.000 35.12388  ? 233 ARG A N     1 
ATOM   1875 C  CA    . ARG A 1 235 ? 11.43038  24.84059 53.27871 1.000 34.10982  ? 233 ARG A CA    1 
ATOM   1876 C  C     . ARG A 1 235 ? 10.64456  25.40700 52.10549 1.000 40.18217  ? 233 ARG A C     1 
ATOM   1877 O  O     . ARG A 1 235 ? 11.14794  26.27256 51.37894 1.000 38.67807  ? 233 ARG A O     1 
ATOM   1878 C  CB    . ARG A 1 235 ? 12.17536  23.57092 52.87862 1.000 37.89303  ? 233 ARG A CB    1 
ATOM   1879 C  CG    . ARG A 1 235 ? 13.14641  23.10288 53.92782 1.000 40.90736  ? 233 ARG A CG    1 
ATOM   1880 C  CD    . ARG A 1 235 ? 14.16052  22.14153 53.35882 1.000 50.15865  ? 233 ARG A CD    1 
ATOM   1881 N  NE    . ARG A 1 235 ? 15.11044  21.72582 54.37923 1.000 51.36435  ? 233 ARG A NE    1 
ATOM   1882 C  CZ    . ARG A 1 235 ? 16.21501  22.39156 54.68592 1.000 59.36401  ? 233 ARG A CZ    1 
ATOM   1883 N  NH1   . ARG A 1 235 ? 16.55690  23.49640 54.04129 1.000 62.16099  ? 233 ARG A NH1   1 
ATOM   1884 N  NH2   . ARG A 1 235 ? 16.99982  21.93357 55.65692 1.000 53.48829  ? 233 ARG A NH2   1 
ATOM   1885 N  N     . LEU A 1 236 ? 9.41089   24.93882 51.89483 1.000 33.74144  ? 234 LEU A N     1 
ATOM   1886 C  CA    . LEU A 1 236 ? 8.58716   25.53936 50.85234 1.000 36.92355  ? 234 LEU A CA    1 
ATOM   1887 C  C     . LEU A 1 236 ? 8.30087   27.00032 51.17344 1.000 38.47015  ? 234 LEU A C     1 
ATOM   1888 O  O     . LEU A 1 236 ? 8.40766   27.86919 50.30315 1.000 33.67134  ? 234 LEU A O     1 
ATOM   1889 C  CB    . LEU A 1 236 ? 7.28364   24.75425 50.66624 1.000 31.32320  ? 234 LEU A CB    1 
ATOM   1890 C  CG    . LEU A 1 236 ? 6.35350   25.35984 49.61213 1.000 33.28559  ? 234 LEU A CG    1 
ATOM   1891 C  CD1   . LEU A 1 236 ? 7.03715   25.35485 48.22760 1.000 32.31973  ? 234 LEU A CD1   1 
ATOM   1892 C  CD2   . LEU A 1 236 ? 5.03500   24.61901 49.53517 1.000 31.14115  ? 234 LEU A CD2   1 
ATOM   1893 N  N     . ASP A 1 237 ? 7.95055   27.29780 52.43152 1.000 32.54370  ? 235 ASP A N     1 
ATOM   1894 C  CA    . ASP A 1 237 ? 7.69279   28.68540 52.79702 1.000 33.95338  ? 235 ASP A CA    1 
ATOM   1895 C  C     . ASP A 1 237 ? 8.93793   29.53902 52.60819 1.000 36.65525  ? 235 ASP A C     1 
ATOM   1896 O  O     . ASP A 1 237 ? 8.84748   30.70011 52.19223 1.000 40.70419  ? 235 ASP A O     1 
ATOM   1897 C  CB    . ASP A 1 237 ? 7.21155   28.79182 54.25102 1.000 35.85899  ? 235 ASP A CB    1 
ATOM   1898 C  CG    . ASP A 1 237 ? 5.72497   28.50659 54.40641 1.000 39.21542  ? 235 ASP A CG    1 
ATOM   1899 O  OD1   . ASP A 1 237 ? 5.02332   28.41126 53.37147 1.000 41.09343  ? 235 ASP A OD1   1 
ATOM   1900 O  OD2   . ASP A 1 237 ? 5.26195   28.41581 55.58154 1.000 40.96918  ? 235 ASP A OD2   1 
ATOM   1901 N  N     . ALA A 1 238 ? 10.11054  28.99511 52.94145 1.000 38.49509  ? 236 ALA A N     1 
ATOM   1902 C  CA    . ALA A 1 238 ? 11.33691  29.76134 52.75472 1.000 43.90813  ? 236 ALA A CA    1 
ATOM   1903 C  C     . ALA A 1 238 ? 11.55908  30.06237 51.27784 1.000 42.81214  ? 236 ALA A C     1 
ATOM   1904 O  O     . ALA A 1 238 ? 11.93871  31.18033 50.91116 1.000 46.01379  ? 236 ALA A O     1 
ATOM   1905 C  CB    . ALA A 1 238 ? 12.52808  29.00755 53.34559 1.000 42.36365  ? 236 ALA A CB    1 
ATOM   1906 N  N     . PHE A 1 239 ? 11.30030  29.08741 50.41327 1.000 39.75361  ? 237 PHE A N     1 
ATOM   1907 C  CA    . PHE A 1 239 ? 11.45240  29.33631 48.98429 1.000 43.35331  ? 237 PHE A CA    1 
ATOM   1908 C  C     . PHE A 1 239 ? 10.49609  30.43529 48.53964 1.000 45.12205  ? 237 PHE A C     1 
ATOM   1909 O  O     . PHE A 1 239 ? 10.88413  31.37218 47.83196 1.000 48.86416  ? 237 PHE A O     1 
ATOM   1910 C  CB    . PHE A 1 239 ? 11.19181  28.06005 48.18674 1.000 38.67633  ? 237 PHE A CB    1 
ATOM   1911 C  CG    . PHE A 1 239 ? 11.19048  28.27705 46.68871 1.000 47.71550  ? 237 PHE A CG    1 
ATOM   1912 C  CD1   . PHE A 1 239 ? 10.09656  28.82495 46.04073 1.000 44.37406  ? 237 PHE A CD1   1 
ATOM   1913 C  CD2   . PHE A 1 239 ? 12.28553  27.90517 45.93290 1.000 51.83756  ? 237 PHE A CD2   1 
ATOM   1914 C  CE1   . PHE A 1 239 ? 10.12300  29.04581 44.67952 1.000 53.41796  ? 237 PHE A CE1   1 
ATOM   1915 C  CE2   . PHE A 1 239 ? 12.29968  28.09813 44.56418 1.000 45.65614  ? 237 PHE A CE2   1 
ATOM   1916 C  CZ    . PHE A 1 239 ? 11.20621  28.65668 43.93882 1.000 50.16103  ? 237 PHE A CZ    1 
ATOM   1917 N  N     . GLU A 1 240 ? 9.23106   30.32733 48.94983 1.000 39.68330  ? 238 GLU A N     1 
ATOM   1918 C  CA    . GLU A 1 240 ? 8.21865   31.29807 48.55457 1.000 40.87423  ? 238 GLU A CA    1 
ATOM   1919 C  C     . GLU A 1 240 ? 8.57476   32.70296 49.01737 1.000 47.72058  ? 238 GLU A C     1 
ATOM   1920 O  O     . GLU A 1 240 ? 8.42744   33.67054 48.26078 1.000 50.82622  ? 238 GLU A O     1 
ATOM   1921 C  CB    . GLU A 1 240 ? 6.85815   30.86939 49.10656 1.000 38.68709  ? 238 GLU A CB    1 
ATOM   1922 C  CG    . GLU A 1 240 ? 6.35508   29.57722 48.47070 1.000 40.91354  ? 238 GLU A CG    1 
ATOM   1923 C  CD    . GLU A 1 240 ? 6.13543   29.72292 46.96007 1.000 41.26892  ? 238 GLU A CD    1 
ATOM   1924 O  OE1   . GLU A 1 240 ? 5.24978   30.50673 46.57680 1.000 40.16834  ? 238 GLU A OE1   1 
ATOM   1925 O  OE2   . GLU A 1 240 ? 6.84874   29.06620 46.16409 1.000 43.08155  ? 238 GLU A OE2   1 
ATOM   1926 N  N     . ARG A 1 241 ? 9.04437   32.84263 50.25801 1.000 45.74315  ? 239 ARG A N     1 
ATOM   1927 C  CA    . ARG A 1 241 ? 9.35959   34.17291 50.75820 1.000 47.21850  ? 239 ARG A CA    1 
ATOM   1928 C  C     . ARG A 1 241 ? 10.62362  34.71512 50.09952 1.000 49.32866  ? 239 ARG A C     1 
ATOM   1929 O  O     . ARG A 1 241 ? 10.71330  35.91072 49.79721 1.000 48.36671  ? 239 ARG A O     1 
ATOM   1930 C  CB    . ARG A 1 241 ? 9.48883   34.11309 52.27833 1.000 47.11931  ? 239 ARG A CB    1 
ATOM   1931 C  CG    . ARG A 1 241 ? 8.12234   34.01620 52.92813 1.000 53.69195  ? 239 ARG A CG    1 
ATOM   1932 C  CD    . ARG A 1 241 ? 8.13387   34.25641 54.42542 1.000 58.10029  ? 239 ARG A CD    1 
ATOM   1933 N  NE    . ARG A 1 241 ? 6.78325   34.52844 54.90584 1.000 68.17619  ? 239 ARG A NE    1 
ATOM   1934 C  CZ    . ARG A 1 241 ? 6.08012   33.69996 55.66670 1.000 67.04923  ? 239 ARG A CZ    1 
ATOM   1935 N  NH1   . ARG A 1 241 ? 6.54878   32.51019 56.00765 1.000 58.28310  ? 239 ARG A NH1   1 
ATOM   1936 N  NH2   . ARG A 1 241 ? 4.86768   34.06487 56.07659 1.000 70.54971  ? 239 ARG A NH2   1 
ATOM   1937 N  N     . ASP A 1 242 ? 11.60234  33.84178 49.85362 1.000 46.41557  ? 240 ASP A N     1 
ATOM   1938 C  CA    . ASP A 1 242 ? 12.81379  34.24631 49.14920 1.000 54.95051  ? 240 ASP A CA    1 
ATOM   1939 C  C     . ASP A 1 242 ? 12.49625  34.70008 47.72666 1.000 51.82092  ? 240 ASP A C     1 
ATOM   1940 O  O     . ASP A 1 242 ? 13.20213  35.54767 47.16517 1.000 51.17774  ? 240 ASP A O     1 
ATOM   1941 C  CB    . ASP A 1 242 ? 13.80646  33.07979 49.15527 1.000 56.59449  ? 240 ASP A CB    1 
ATOM   1942 C  CG    . ASP A 1 242 ? 15.18810  33.47106 48.66893 1.000 71.59593  ? 240 ASP A CG    1 
ATOM   1943 O  OD1   . ASP A 1 242 ? 15.30890  34.41531 47.86143 1.000 73.04396  ? 240 ASP A OD1   1 
ATOM   1944 O  OD2   . ASP A 1 242 ? 16.16549  32.83308 49.11380 1.000 77.14729  ? 240 ASP A OD2   1 
ATOM   1945 N  N     . ALA A 1 243 ? 11.43590  34.16043 47.13692 1.000 48.19416  ? 241 ALA A N     1 
ATOM   1946 C  CA    . ALA A 1 243 ? 10.96097  34.58108 45.82676 1.000 55.75180  ? 241 ALA A CA    1 
ATOM   1947 C  C     . ALA A 1 243 ? 10.01966  35.77336 45.90523 1.000 54.33289  ? 241 ALA A C     1 
ATOM   1948 O  O     . ALA A 1 243 ? 9.53919   36.23471 44.86669 1.000 57.92241  ? 241 ALA A O     1 
ATOM   1949 C  CB    . ALA A 1 243 ? 10.26335  33.41447 45.11706 1.000 48.63538  ? 241 ALA A CB    1 
ATOM   1950 N  N     . GLY A 1 244 ? 9.74438   36.27805 47.10614 1.000 50.51359  ? 242 GLY A N     1 
ATOM   1951 C  CA    . GLY A 1 244 ? 8.89663   37.43748 47.28709 1.000 50.61883  ? 242 GLY A CA    1 
ATOM   1952 C  C     . GLY A 1 244 ? 7.44339   37.14089 47.58435 1.000 56.04336  ? 242 GLY A C     1 
ATOM   1953 O  O     . GLY A 1 244 ? 6.67746   38.08272 47.82310 1.000 63.82586  ? 242 GLY A O     1 
ATOM   1954 N  N     . ARG A 1 245 ? 7.03983   35.87266 47.58176 1.000 54.72115  ? 243 ARG A N     1 
ATOM   1955 C  CA    . ARG A 1 245 ? 5.66478   35.48775 47.86032 1.000 52.35753  ? 243 ARG A CA    1 
ATOM   1956 C  C     . ARG A 1 245 ? 5.48646   35.16844 49.34580 1.000 57.11523  ? 243 ARG A C     1 
ATOM   1957 O  O     . ARG A 1 245 ? 6.45150   35.01255 50.09769 1.000 58.40511  ? 243 ARG A O     1 
ATOM   1958 C  CB    . ARG A 1 245 ? 5.25752   34.30034 46.97666 1.000 49.02447  ? 243 ARG A CB    1 
ATOM   1959 C  CG    . ARG A 1 245 ? 4.93367   34.72683 45.54931 1.000 47.06206  ? 243 ARG A CG    1 
ATOM   1960 C  CD    . ARG A 1 245 ? 4.97121   33.62152 44.48916 1.000 44.30669  ? 243 ARG A CD    1 
ATOM   1961 N  NE    . ARG A 1 245 ? 5.87859   32.50694 44.73756 1.000 38.70060  ? 243 ARG A NE    1 
ATOM   1962 C  CZ    . ARG A 1 245 ? 6.93430   32.21941 43.98598 1.000 44.20065  ? 243 ARG A CZ    1 
ATOM   1963 N  NH1   . ARG A 1 245 ? 7.32051   33.01456 43.00020 1.000 48.21164  ? 243 ARG A NH1   1 
ATOM   1964 N  NH2   . ARG A 1 245 ? 7.63154   31.11451 44.23764 1.000 46.66059  ? 243 ARG A NH2   1 
ATOM   1965 N  N     . LYS A 1 246 ? 4.22771   35.08692 49.77170 1.000 54.56315  ? 244 LYS A N     1 
ATOM   1966 C  CA    . LYS A 1 246 ? 3.91766   34.88860 51.17731 1.000 51.12249  ? 244 LYS A CA    1 
ATOM   1967 C  C     . LYS A 1 246 ? 3.88235   33.39628 51.51643 1.000 48.09763  ? 244 LYS A C     1 
ATOM   1968 O  O     . LYS A 1 246 ? 4.02041   32.52825 50.65195 1.000 45.02819  ? 244 LYS A O     1 
ATOM   1969 C  CB    . LYS A 1 246 ? 2.59795   35.57525 51.53103 1.000 58.69235  ? 244 LYS A CB    1 
ATOM   1970 N  N     . GLY A 1 247 ? 3.70839   33.09258 52.80274 1.000 51.07775  ? 245 GLY A N     1 
ATOM   1971 C  CA    . GLY A 1 247 ? 3.70637   31.70747 53.23446 1.000 45.95981  ? 245 GLY A CA    1 
ATOM   1972 C  C     . GLY A 1 247 ? 2.53029   30.93242 52.67064 1.000 40.22451  ? 245 GLY A C     1 
ATOM   1973 O  O     . GLY A 1 247 ? 1.45595   31.47722 52.41694 1.000 44.11992  ? 245 GLY A O     1 
ATOM   1974 N  N     . VAL A 1 248 ? 2.73968   29.63586 52.47207 1.000 36.02305  ? 246 VAL A N     1 
ATOM   1975 C  CA    . VAL A 1 248 ? 1.70759   28.78812 51.88495 1.000 34.17074  ? 246 VAL A CA    1 
ATOM   1976 C  C     . VAL A 1 248 ? 0.73246   28.36715 52.96930 1.000 41.29362  ? 246 VAL A C     1 
ATOM   1977 O  O     . VAL A 1 248 ? 1.13742   27.90682 54.04282 1.000 38.23071  ? 246 VAL A O     1 
ATOM   1978 C  CB    . VAL A 1 248 ? 2.31639   27.55802 51.20692 1.000 32.82754  ? 246 VAL A CB    1 
ATOM   1979 C  CG1   . VAL A 1 248 ? 1.20781   26.75583 50.51086 1.000 35.75881  ? 246 VAL A CG1   1 
ATOM   1980 C  CG2   . VAL A 1 248 ? 3.38488   27.97462 50.19952 1.000 36.08317  ? 246 VAL A CG2   1 
ATOM   1981 N  N     . ASP A 1 249 ? -0.55749  28.50838 52.69618 1.000 36.72944  ? 247 ASP A N     1 
ATOM   1982 C  CA    . ASP A 1 249 ? -1.51655  28.16975 53.73537 1.000 39.17918  ? 247 ASP A CA    1 
ATOM   1983 C  C     . ASP A 1 249 ? -1.55481  26.65631 53.94385 1.000 29.30979  ? 247 ASP A C     1 
ATOM   1984 O  O     . ASP A 1 249 ? -1.22830  25.86599 53.04296 1.000 31.67810  ? 247 ASP A O     1 
ATOM   1985 C  CB    . ASP A 1 249 ? -2.90169  28.71437 53.39549 1.000 38.90677  ? 247 ASP A CB    1 
ATOM   1986 C  CG    . ASP A 1 249 ? -3.51115  28.02581 52.21332 1.000 47.03804  ? 247 ASP A CG    1 
ATOM   1987 O  OD1   . ASP A 1 249 ? -3.17329  28.40741 51.07242 1.000 52.68978  ? 247 ASP A OD1   1 
ATOM   1988 O  OD2   . ASP A 1 249 ? -4.31680  27.09598 52.42690 1.000 54.14874  ? 247 ASP A OD2   1 
ATOM   1989 N  N     . ALA A 1 250 ? -1.93949  26.25776 55.16731 1.000 36.77613  ? 248 ALA A N     1 
ATOM   1990 C  CA    . ALA A 1 250 ? -1.81975  24.85625 55.55160 1.000 36.84251  ? 248 ALA A CA    1 
ATOM   1991 C  C     . ALA A 1 250 ? -2.65934  23.94946 54.65837 1.000 32.60901  ? 248 ALA A C     1 
ATOM   1992 O  O     . ALA A 1 250 ? -2.21632  22.86077 54.28405 1.000 32.48175  ? 248 ALA A O     1 
ATOM   1993 C  CB    . ALA A 1 250 ? -2.20509  24.68399 57.02314 1.000 36.19472  ? 248 ALA A CB    1 
ATOM   1994 N  N     . ALA A 1 251 ? -3.88047  24.37063 54.31368 1.000 35.90955  ? 249 ALA A N     1 
ATOM   1995 C  CA    . ALA A 1 251 ? -4.70814  23.54273 53.43840 1.000 36.69001  ? 249 ALA A CA    1 
ATOM   1996 C  C     . ALA A 1 251 ? -4.04689  23.31884 52.07873 1.000 36.64165  ? 249 ALA A C     1 
ATOM   1997 O  O     . ALA A 1 251 ? -4.08537  22.20777 51.53670 1.000 35.43419  ? 249 ALA A O     1 
ATOM   1998 C  CB    . ALA A 1 251 ? -6.08622  24.17563 53.26737 1.000 34.90892  ? 249 ALA A CB    1 
ATOM   1999 N  N     . THR A 1 252 ? -3.41894  24.35414 51.51468 1.000 33.23971  ? 250 THR A N     1 
ATOM   2000 C  CA    . THR A 1 252 ? -2.81168  24.21361 50.19389 1.000 33.46055  ? 250 THR A CA    1 
ATOM   2001 C  C     . THR A 1 252 ? -1.58568  23.31493 50.25350 1.000 28.92575  ? 250 THR A C     1 
ATOM   2002 O  O     . THR A 1 252 ? -1.41690  22.42621 49.40895 1.000 26.94269  ? 250 THR A O     1 
ATOM   2003 C  CB    . THR A 1 252 ? -2.45275  25.59048 49.64065 1.000 31.74526  ? 250 THR A CB    1 
ATOM   2004 O  OG1   . THR A 1 252 ? -3.65084  26.37668 49.53260 1.000 33.12709  ? 250 THR A OG1   1 
ATOM   2005 C  CG2   . THR A 1 252 ? -1.74705  25.47335 48.27120 1.000 31.11290  ? 250 THR A CG2   1 
ATOM   2006 N  N     . PHE A 1 253 ? -0.74539  23.50048 51.28106 1.000 28.12323  ? 251 PHE A N     1 
ATOM   2007 C  CA    . PHE A 1 253 ? 0.41457   22.63608 51.44714 1.000 30.58991  ? 251 PHE A CA    1 
ATOM   2008 C  C     . PHE A 1 253 ? -0.00645  21.17486 51.55408 1.000 27.57753  ? 251 PHE A C     1 
ATOM   2009 O  O     . PHE A 1 253 ? 0.51150   20.31399 50.82956 1.000 29.43105  ? 251 PHE A O     1 
ATOM   2010 C  CB    . PHE A 1 253 ? 1.22191   23.05805 52.67782 1.000 29.46861  ? 251 PHE A CB    1 
ATOM   2011 C  CG    . PHE A 1 253 ? 2.32218   22.10532 53.01591 1.000 32.34002  ? 251 PHE A CG    1 
ATOM   2012 C  CD1   . PHE A 1 253 ? 3.50631   22.11368 52.29455 1.000 34.14046  ? 251 PHE A CD1   1 
ATOM   2013 C  CD2   . PHE A 1 253 ? 2.16469   21.17111 54.02788 1.000 34.82659  ? 251 PHE A CD2   1 
ATOM   2014 C  CE1   . PHE A 1 253 ? 4.52204   21.23549 52.60571 1.000 30.85386  ? 251 PHE A CE1   1 
ATOM   2015 C  CE2   . PHE A 1 253 ? 3.17950   20.28253 54.32471 1.000 34.41450  ? 251 PHE A CE2   1 
ATOM   2016 C  CZ    . PHE A 1 253 ? 4.35137   20.31392 53.59609 1.000 28.08859  ? 251 PHE A CZ    1 
ATOM   2017 N  N     . THR A 1 254 ? -0.95838  20.87549 52.44155 1.000 29.36713  ? 252 THR A N     1 
ATOM   2018 C  CA    . THR A 1 254 ? -1.31124  19.47771 52.67546 1.000 30.86206  ? 252 THR A CA    1 
ATOM   2019 C  C     . THR A 1 254 ? -1.99083  18.87824 51.44684 1.000 32.00172  ? 252 THR A C     1 
ATOM   2020 O  O     . THR A 1 254 ? -1.76242  17.71107 51.11956 1.000 30.67550  ? 252 THR A O     1 
ATOM   2021 C  CB    . THR A 1 254 ? -2.17960  19.32946 53.93745 1.000 37.84066  ? 252 THR A CB    1 
ATOM   2022 O  OG1   . THR A 1 254 ? -3.41262  20.02806 53.79221 1.000 39.45734  ? 252 THR A OG1   1 
ATOM   2023 C  CG2   . THR A 1 254 ? -1.47699  19.89857 55.15583 1.000 35.04663  ? 252 THR A CG2   1 
ATOM   2024 N  N     . SER A 1 255 ? -2.78865  19.67379 50.72633 1.000 30.40273  ? 253 SER A N     1 
ATOM   2025 C  CA    . SER A 1 255 ? -3.46431  19.15522 49.53514 1.000 30.91118  ? 253 SER A CA    1 
ATOM   2026 C  C     . SER A 1 255 ? -2.46696  18.83924 48.42540 1.000 30.03989  ? 253 SER A C     1 
ATOM   2027 O  O     . SER A 1 255 ? -2.53872  17.77600 47.79480 1.000 28.13302  ? 253 SER A O     1 
ATOM   2028 C  CB    . SER A 1 255 ? -4.52455  20.15633 49.05875 1.000 30.84971  ? 253 SER A CB    1 
ATOM   2029 O  OG    . SER A 1 255 ? -5.08248  19.74882 47.81773 1.000 32.93503  ? 253 SER A OG    1 
ATOM   2030 N  N     . ILE A 1 256 ? -1.51852  19.74586 48.17401 1.000 25.44553  ? 254 ILE A N     1 
ATOM   2031 C  CA    . ILE A 1 256 ? -0.52221  19.50634 47.13571 1.000 25.62854  ? 254 ILE A CA    1 
ATOM   2032 C  C     . ILE A 1 256 ? 0.31748   18.28995 47.48433 1.000 28.85731  ? 254 ILE A C     1 
ATOM   2033 O  O     . ILE A 1 256 ? 0.56622   17.42809 46.63770 1.000 25.72949  ? 254 ILE A O     1 
ATOM   2034 C  CB    . ILE A 1 256 ? 0.35628   20.75007 46.92629 1.000 24.83399  ? 254 ILE A CB    1 
ATOM   2035 C  CG1   . ILE A 1 256 ? -0.47011  21.89923 46.34451 1.000 25.52177  ? 254 ILE A CG1   1 
ATOM   2036 C  CG2   . ILE A 1 256 ? 1.50302   20.43659 45.96560 1.000 26.60013  ? 254 ILE A CG2   1 
ATOM   2037 C  CD1   . ILE A 1 256 ? 0.23846   23.23534 46.37436 1.000 27.27323  ? 254 ILE A CD1   1 
ATOM   2038 N  N     . VAL A 1 257 ? 0.75113   18.18573 48.74603 1.000 27.33528  ? 255 VAL A N     1 
ATOM   2039 C  CA    . VAL A 1 257 ? 1.58673   17.04993 49.12368 1.000 26.18777  ? 255 VAL A CA    1 
ATOM   2040 C  C     . VAL A 1 257 ? 0.81517   15.74748 48.96871 1.000 26.26143  ? 255 VAL A C     1 
ATOM   2041 O  O     . VAL A 1 257 ? 1.35172   14.74710 48.47710 1.000 28.66626  ? 255 VAL A O     1 
ATOM   2042 C  CB    . VAL A 1 257 ? 2.12360   17.23292 50.55312 1.000 30.01033  ? 255 VAL A CB    1 
ATOM   2043 C  CG1   . VAL A 1 257 ? 2.70210   15.92290 51.05115 1.000 33.64585  ? 255 VAL A CG1   1 
ATOM   2044 C  CG2   . VAL A 1 257 ? 3.17587   18.32781 50.54886 1.000 28.82588  ? 255 VAL A CG2   1 
ATOM   2045 N  N     . ALA A 1 258 ? -0.46240  15.74608 49.34962 1.000 26.24555  ? 256 ALA A N     1 
ATOM   2046 C  CA    . ALA A 1 258 ? -1.27211  14.54651 49.18047 1.000 27.98762  ? 256 ALA A CA    1 
ATOM   2047 C  C     . ALA A 1 258 ? -1.33764  14.15584 47.70728 1.000 27.17602  ? 256 ALA A C     1 
ATOM   2048 O  O     . ALA A 1 258 ? -1.27638  12.96809 47.36467 1.000 27.89843  ? 256 ALA A O     1 
ATOM   2049 C  CB    . ALA A 1 258 ? -2.67665  14.77018 49.74877 1.000 33.00788  ? 256 ALA A CB    1 
ATOM   2050 N  N     . ASP A 1 259 ? -1.45891  15.15281 46.82936 1.000 25.43477  ? 257 ASP A N     1 
ATOM   2051 C  CA    . ASP A 1 259 ? -1.51698  14.89846 45.39187 1.000 28.12687  ? 257 ASP A CA    1 
ATOM   2052 C  C     . ASP A 1 259 ? -0.20628  14.27342 44.91986 1.000 26.09792  ? 257 ASP A C     1 
ATOM   2053 O  O     . ASP A 1 259 ? -0.19289  13.29515 44.15805 1.000 27.49793  ? 257 ASP A O     1 
ATOM   2054 C  CB    . ASP A 1 259 ? -1.75360  16.22931 44.65624 1.000 26.75960  ? 257 ASP A CB    1 
ATOM   2055 C  CG    . ASP A 1 259 ? -3.23443  16.64977 44.61447 1.000 31.61713  ? 257 ASP A CG    1 
ATOM   2056 O  OD1   . ASP A 1 259 ? -4.10605  15.93425 45.16848 1.000 34.14265  ? 257 ASP A OD1   1 
ATOM   2057 O  OD2   . ASP A 1 259 ? -3.52267  17.74139 44.06114 1.000 31.36325  ? 257 ASP A OD2   1 
ATOM   2058 N  N     . LEU A 1 260 ? 0.91773   14.83360 45.36607 1.000 23.72739  ? 258 LEU A N     1 
ATOM   2059 C  CA    . LEU A 1 260 ? 2.21243   14.36052 44.87968 1.000 26.38211  ? 258 LEU A CA    1 
ATOM   2060 C  C     . LEU A 1 260 ? 2.49113   12.93912 45.34661 1.000 26.53743  ? 258 LEU A C     1 
ATOM   2061 O  O     . LEU A 1 260 ? 3.06956   12.13125 44.60459 1.000 26.17225  ? 258 LEU A O     1 
ATOM   2062 C  CB    . LEU A 1 260 ? 3.31521   15.31390 45.33284 1.000 27.46272  ? 258 LEU A CB    1 
ATOM   2063 C  CG    . LEU A 1 260 ? 3.26609   16.71620 44.70633 1.000 26.90282  ? 258 LEU A CG    1 
ATOM   2064 C  CD1   . LEU A 1 260 ? 4.30934   17.64264 45.35706 1.000 23.98664  ? 258 LEU A CD1   1 
ATOM   2065 C  CD2   . LEU A 1 260 ? 3.43066   16.66764 43.15568 1.000 23.49922  ? 258 LEU A CD2   1 
ATOM   2066 N  N     . VAL A 1 261 ? 2.08863   12.60984 46.57453 1.000 25.06693  ? 259 VAL A N     1 
ATOM   2067 C  CA    . VAL A 1 261 ? 2.22944   11.23651 47.03727 1.000 24.73671  ? 259 VAL A CA    1 
ATOM   2068 C  C     . VAL A 1 261 ? 1.32593   10.31561 46.23316 1.000 26.77708  ? 259 VAL A C     1 
ATOM   2069 O  O     . VAL A 1 261 ? 1.74120   9.22848  45.80476 1.000 29.28953  ? 259 VAL A O     1 
ATOM   2070 C  CB    . VAL A 1 261 ? 1.94162   11.14863 48.54913 1.000 29.86929  ? 259 VAL A CB    1 
ATOM   2071 C  CG1   . VAL A 1 261 ? 1.98503   9.71546  49.00620 1.000 29.57368  ? 259 VAL A CG1   1 
ATOM   2072 C  CG2   . VAL A 1 261 ? 2.94713   11.98297 49.32519 1.000 31.69740  ? 259 VAL A CG2   1 
ATOM   2073 N  N     . ALA A 1 262 ? 0.08287   10.74225 45.98798 1.000 26.33910  ? 260 ALA A N     1 
ATOM   2074 C  CA    . ALA A 1 262 ? -0.84630  9.89015  45.25436 1.000 28.16609  ? 260 ALA A CA    1 
ATOM   2075 C  C     . ALA A 1 262 ? -0.34470  9.63456  43.84205 1.000 26.71038  ? 260 ALA A C     1 
ATOM   2076 O  O     . ALA A 1 262 ? -0.52908  8.53877  43.30115 1.000 29.86893  ? 260 ALA A O     1 
ATOM   2077 C  CB    . ALA A 1 262 ? -2.24433  10.51717 45.22176 1.000 28.63400  ? 260 ALA A CB    1 
ATOM   2078 N  N     . GLU A 1 263 ? 0.31463   10.62944 43.24509 1.000 25.74447  ? 261 GLU A N     1 
ATOM   2079 C  CA    . GLU A 1 263 ? 0.80258   10.49177 41.87423 1.000 28.34253  ? 261 GLU A CA    1 
ATOM   2080 C  C     . GLU A 1 263 ? 2.08783   9.68319  41.78653 1.000 29.94841  ? 261 GLU A C     1 
ATOM   2081 O  O     . GLU A 1 263 ? 2.44104   9.22142  40.69037 1.000 31.31688  ? 261 GLU A O     1 
ATOM   2082 C  CB    . GLU A 1 263 ? 0.99603   11.87655 41.25513 1.000 25.74503  ? 261 GLU A CB    1 
ATOM   2083 C  CG    . GLU A 1 263 ? -0.32825  12.61997 41.12499 1.000 29.88641  ? 261 GLU A CG    1 
ATOM   2084 C  CD    . GLU A 1 263 ? -0.17707  14.00718 40.55109 1.000 30.80213  ? 261 GLU A CD    1 
ATOM   2085 O  OE1   . GLU A 1 263 ? 0.82180   14.24610 39.83329 1.000 29.08053  ? 261 GLU A OE1   1 
ATOM   2086 O  OE2   . GLU A 1 263 ? -1.05336  14.85944 40.80960 1.000 28.67227  ? 261 GLU A OE2   1 
ATOM   2087 N  N     . GLY A 1 264 ? 2.77453   9.47780  42.90502 1.000 30.02465  ? 262 GLY A N     1 
ATOM   2088 C  CA    . GLY A 1 264 ? 3.97158   8.67143  42.92798 1.000 30.21457  ? 262 GLY A CA    1 
ATOM   2089 C  C     . GLY A 1 264 ? 5.28957   9.41391  42.88762 1.000 25.72539  ? 262 GLY A C     1 
ATOM   2090 O  O     . GLY A 1 264 ? 6.31538   8.77970  42.61693 1.000 31.88665  ? 262 GLY A O     1 
ATOM   2091 N  N     . PHE A 1 265 ? 5.31305   10.71749 43.19166 1.000 26.04497  ? 263 PHE A N     1 
ATOM   2092 C  CA    . PHE A 1 265 ? 6.59076   11.43239 43.16369 1.000 26.85224  ? 263 PHE A CA    1 
ATOM   2093 C  C     . PHE A 1 265 ? 7.45881   11.11115 44.36576 1.000 29.19997  ? 263 PHE A C     1 
ATOM   2094 O  O     . PHE A 1 265 ? 8.69238   11.09311 44.25854 1.000 28.19010  ? 263 PHE A O     1 
ATOM   2095 C  CB    . PHE A 1 265 ? 6.34701   12.93000 43.06452 1.000 26.78748  ? 263 PHE A CB    1 
ATOM   2096 C  CG    . PHE A 1 265 ? 5.91647   13.33555 41.69680 1.000 24.55115  ? 263 PHE A CG    1 
ATOM   2097 C  CD1   . PHE A 1 265 ? 6.85576   13.45394 40.67833 1.000 25.59606  ? 263 PHE A CD1   1 
ATOM   2098 C  CD2   . PHE A 1 265 ? 4.57504   13.50976 41.41356 1.000 25.24607  ? 263 PHE A CD2   1 
ATOM   2099 C  CE1   . PHE A 1 265 ? 6.45551   13.79139 39.38100 1.000 31.09342  ? 263 PHE A CE1   1 
ATOM   2100 C  CE2   . PHE A 1 265 ? 4.16319   13.83859 40.13203 1.000 24.00656  ? 263 PHE A CE2   1 
ATOM   2101 C  CZ    . PHE A 1 265 ? 5.11196   13.97693 39.11157 1.000 26.88911  ? 263 PHE A CZ    1 
ATOM   2102 N  N     . PHE A 1 266 ? 6.84149   10.85068 45.50562 1.000 28.60128  ? 264 PHE A N     1 
ATOM   2103 C  CA    . PHE A 1 266 ? 7.58899   10.38614 46.66132 1.000 28.34275  ? 264 PHE A CA    1 
ATOM   2104 C  C     . PHE A 1 266 ? 6.59931   9.69567  47.58517 1.000 29.99787  ? 264 PHE A C     1 
ATOM   2105 O  O     . PHE A 1 266 ? 5.38462   9.73148  47.36174 1.000 30.43724  ? 264 PHE A O     1 
ATOM   2106 C  CB    . PHE A 1 266 ? 8.34465   11.53135 47.34983 1.000 29.80339  ? 264 PHE A CB    1 
ATOM   2107 C  CG    . PHE A 1 266 ? 7.52249   12.77332 47.59665 1.000 30.01787  ? 264 PHE A CG    1 
ATOM   2108 C  CD1   . PHE A 1 266 ? 6.66590   12.85823 48.68513 1.000 34.68988  ? 264 PHE A CD1   1 
ATOM   2109 C  CD2   . PHE A 1 266 ? 7.66339   13.88182 46.77358 1.000 30.77343  ? 264 PHE A CD2   1 
ATOM   2110 C  CE1   . PHE A 1 266 ? 5.92724   14.01716 48.92904 1.000 35.88102  ? 264 PHE A CE1   1 
ATOM   2111 C  CE2   . PHE A 1 266 ? 6.93546   15.04311 47.00317 1.000 31.03151  ? 264 PHE A CE2   1 
ATOM   2112 C  CZ    . PHE A 1 266 ? 6.05870   15.11305 48.08681 1.000 30.76809  ? 264 PHE A CZ    1 
ATOM   2113 N  N     . ARG A 1 267 ? 7.13480   9.01529  48.59296 1.000 33.53641  ? 265 ARG A N     1 
ATOM   2114 C  CA    . ARG A 1 267 ? 6.30507   8.26698  49.52440 1.000 35.37331  ? 265 ARG A CA    1 
ATOM   2115 C  C     . ARG A 1 267 ? 6.47274   8.81173  50.93144 1.000 39.14772  ? 265 ARG A C     1 
ATOM   2116 O  O     . ARG A 1 267 ? 7.46072   9.47766  51.25503 1.000 35.82916  ? 265 ARG A O     1 
ATOM   2117 C  CB    . ARG A 1 267 ? 6.64686   6.77325  49.51606 1.000 37.54107  ? 265 ARG A CB    1 
ATOM   2118 C  CG    . ARG A 1 267 ? 8.10778   6.49353  49.72012 1.000 43.87973  ? 265 ARG A CG    1 
ATOM   2119 C  CD    . ARG A 1 267 ? 8.42407   5.02146  49.57051 1.000 49.32809  ? 265 ARG A CD    1 
ATOM   2120 N  NE    . ARG A 1 267 ? 9.66199   4.68349  50.26087 1.000 58.11208  ? 265 ARG A NE    1 
ATOM   2121 C  CZ    . ARG A 1 267 ? 10.87091  4.79504  49.72566 1.000 57.84561  ? 265 ARG A CZ    1 
ATOM   2122 N  NH1   . ARG A 1 267 ? 11.04199  5.22653  48.48432 1.000 56.24573  ? 265 ARG A NH1   1 
ATOM   2123 N  NH2   . ARG A 1 267 ? 11.93538  4.46694  50.45458 1.000 61.04417  ? 265 ARG A NH2   1 
ATOM   2124 N  N     . ARG A 1 268 ? 5.48586   8.50140  51.76588 1.000 42.23201  ? 266 ARG A N     1 
ATOM   2125 C  CA    . ARG A 1 268 ? 5.50899   8.82156  53.18474 1.000 46.29845  ? 266 ARG A CA    1 
ATOM   2126 C  C     . ARG A 1 268 ? 5.95988   7.60029  53.97194 1.000 43.63231  ? 266 ARG A C     1 
ATOM   2127 O  O     . ARG A 1 268 ? 5.38499   6.51692  53.82964 1.000 44.23136  ? 266 ARG A O     1 
ATOM   2128 C  CB    . ARG A 1 268 ? 4.12593   9.25959  53.66860 1.000 48.30018  ? 266 ARG A CB    1 
ATOM   2129 C  CG    . ARG A 1 268 ? 4.11723   9.76821  55.09846 1.000 56.30937  ? 266 ARG A CG    1 
ATOM   2130 C  CD    . ARG A 1 268 ? 2.71802   10.15637 55.52430 1.000 63.38606  ? 266 ARG A CD    1 
ATOM   2131 N  NE    . ARG A 1 268 ? 2.68820   11.47519 56.14101 1.000 73.30353  ? 266 ARG A NE    1 
ATOM   2132 C  CZ    . ARG A 1 268 ? 2.01970   11.77468 57.24671 1.000 63.99221  ? 266 ARG A CZ    1 
ATOM   2133 N  NH1   . ARG A 1 268 ? 1.35626   10.85322 57.92749 1.000 71.01233  ? 266 ARG A NH1   1 
ATOM   2134 N  NH2   . ARG A 1 268 ? 2.02145   13.02990 57.68196 1.000 64.54280  ? 266 ARG A NH2   1 
ATOM   2135 N  N     . GLU A 1 269 ? 6.98853   7.77336  54.79372 1.000 49.28211  ? 267 GLU A N     1 
ATOM   2136 C  CA    . GLU A 1 269 ? 7.40312   6.75186  55.74989 1.000 55.00888  ? 267 GLU A CA    1 
ATOM   2137 C  C     . GLU A 1 269 ? 7.36982   7.43442  57.11422 1.000 57.80730  ? 267 GLU A C     1 
ATOM   2138 O  O     . GLU A 1 269 ? 8.29770   8.16506  57.47417 1.000 54.68748  ? 267 GLU A O     1 
ATOM   2139 C  CB    . GLU A 1 269 ? 8.77475   6.17950  55.39451 1.000 55.63573  ? 267 GLU A CB    1 
ATOM   2140 C  CG    . GLU A 1 269 ? 8.68285   5.11649  54.30075 1.000 64.52778  ? 267 GLU A CG    1 
ATOM   2141 C  CD    . GLU A 1 269 ? 10.03177  4.60585  53.82627 1.000 70.89945  ? 267 GLU A CD    1 
ATOM   2142 O  OE1   . GLU A 1 269 ? 10.93867  4.43483  54.67004 1.000 68.19961  ? 267 GLU A OE1   1 
ATOM   2143 O  OE2   . GLU A 1 269 ? 10.18766  4.39226  52.59978 1.000 66.60719  ? 267 GLU A OE2   1 
ATOM   2144 N  N     A GLY A 1 270 ? 6.32639   7.10228  57.87738 0.550 62.58004  ? 268 GLY A N     1 
ATOM   2145 N  N     B GLY A 1 270 ? 6.26128   7.29226  57.83893 0.450 62.35758  ? 268 GLY A N     1 
ATOM   2146 C  CA    A GLY A 1 270 ? 6.02794   7.72690  59.14636 0.550 58.34661  ? 268 GLY A CA    1 
ATOM   2147 C  CA    B GLY A 1 270 ? 6.12296   7.91494  59.14989 0.450 58.43761  ? 268 GLY A CA    1 
ATOM   2148 C  C     A GLY A 1 270 ? 5.51569   9.12610  58.90491 0.550 58.98341  ? 268 GLY A C     1 
ATOM   2149 C  C     B GLY A 1 270 ? 6.58317   9.36143  59.27452 0.450 58.61503  ? 268 GLY A C     1 
ATOM   2150 O  O     A GLY A 1 270 ? 4.41391   9.32611  58.38041 0.550 56.05232  ? 268 GLY A O     1 
ATOM   2151 O  O     B GLY A 1 270 ? 7.66073   9.63104  59.81350 0.450 54.52075  ? 268 GLY A O     1 
ATOM   2152 N  N     A ASP A 1 271 ? 6.33386   10.10511 59.26502 0.770 57.56005  ? 269 ASP A N     1 
ATOM   2153 N  N     B ASP A 1 271 ? 5.76963   10.30065 58.79026 0.230 59.03779  ? 269 ASP A N     1 
ATOM   2154 C  CA    A ASP A 1 271 ? 6.05871   11.49443 58.95844 0.770 61.76516  ? 269 ASP A CA    1 
ATOM   2155 C  CA    B ASP A 1 271 ? 6.01186   11.74435 58.83535 0.230 61.38885  ? 269 ASP A CA    1 
ATOM   2156 C  C     A ASP A 1 271 ? 7.07887   12.08913 57.99209 0.770 57.39174  ? 269 ASP A C     1 
ATOM   2157 C  C     B ASP A 1 271 ? 7.31649   12.16871 58.17580 0.230 57.81173  ? 269 ASP A C     1 
ATOM   2158 O  O     A ASP A 1 271 ? 7.00155   13.28522 57.68828 0.770 60.27013  ? 269 ASP A O     1 
ATOM   2159 O  O     B ASP A 1 271 ? 7.72510   13.32765 58.32357 0.230 56.80582  ? 269 ASP A O     1 
ATOM   2160 C  CB    . ASP A 1 271 ? 5.98723   12.29723 60.26445 1.000 64.70498  ? 269 ASP A CB    1 
ATOM   2161 C  CG    A ASP A 1 271 ? 4.69516   12.05849 61.01681 0.770 60.01053  ? 269 ASP A CG    1 
ATOM   2162 O  OD1   A ASP A 1 271 ? 3.61574   12.24115 60.40837 0.770 61.60954  ? 269 ASP A OD1   1 
ATOM   2163 O  OD2   A ASP A 1 271 ? 4.74817   11.69299 62.20397 0.770 62.35146  ? 269 ASP A OD2   1 
ATOM   2164 N  N     . ALA A 1 272 ? 7.99914   11.27396 57.47202 1.000 58.32436  ? 270 ALA A N     1 
ATOM   2165 C  CA    . ALA A 1 272 ? 9.09457   11.68469 56.60375 1.000 46.95183  ? 270 ALA A CA    1 
ATOM   2166 C  C     . ALA A 1 272 ? 8.79605   11.27437 55.16786 1.000 46.21990  ? 270 ALA A C     1 
ATOM   2167 O  O     . ALA A 1 272 ? 8.02999   10.34063 54.91445 1.000 46.08442  ? 270 ALA A O     1 
ATOM   2168 C  CB    . ALA A 1 272 ? 10.42528  11.07290 57.04959 1.000 49.06627  ? 270 ALA A CB    1 
ATOM   2169 N  N     . PHE A 1 273 ? 9.40611   11.99121 54.22377 1.000 41.69283  ? 271 PHE A N     1 
ATOM   2170 C  CA    . PHE A 1 273 ? 9.18016   11.76417 52.80232 1.000 37.30336  ? 271 PHE A CA    1 
ATOM   2171 C  C     . PHE A 1 273 ? 10.45225  11.28481 52.11728 1.000 39.04900  ? 271 PHE A C     1 
ATOM   2172 O  O     . PHE A 1 273 ? 11.54478  11.77389 52.41009 1.000 41.00150  ? 271 PHE A O     1 
ATOM   2173 C  CB    . PHE A 1 273 ? 8.68313   13.03924 52.11448 1.000 36.94795  ? 271 PHE A CB    1 
ATOM   2174 C  CG    . PHE A 1 273 ? 7.30450   13.45060 52.53227 1.000 36.97581  ? 271 PHE A CG    1 
ATOM   2175 C  CD1   . PHE A 1 273 ? 6.21605   12.64081 52.26127 1.000 35.56187  ? 271 PHE A CD1   1 
ATOM   2176 C  CD2   . PHE A 1 273 ? 7.09854   14.64604 53.20416 1.000 38.93890  ? 271 PHE A CD2   1 
ATOM   2177 C  CE1   . PHE A 1 273 ? 4.93511   13.01280 52.65382 1.000 40.67886  ? 271 PHE A CE1   1 
ATOM   2178 C  CE2   . PHE A 1 273 ? 5.82118   15.03000 53.59179 1.000 42.61748  ? 271 PHE A CE2   1 
ATOM   2179 C  CZ    . PHE A 1 273 ? 4.73980   14.20927 53.31739 1.000 39.31202  ? 271 PHE A CZ    1 
ATOM   2180 N  N     . PHE A 1 274 ? 10.29432  10.34737 51.17526 1.000 37.95900  ? 272 PHE A N     1 
ATOM   2181 C  CA    . PHE A 1 274 ? 11.40554  9.78949  50.40944 1.000 35.02261  ? 272 PHE A CA    1 
ATOM   2182 C  C     . PHE A 1 274 ? 11.01133  9.68404  48.94406 1.000 37.24870  ? 272 PHE A C     1 
ATOM   2183 O  O     . PHE A 1 274 ? 9.96954   9.10715  48.61530 1.000 33.66662  ? 272 PHE A O     1 
ATOM   2184 C  CB    . PHE A 1 274 ? 11.81899  8.39894  50.91594 1.000 39.58669  ? 272 PHE A CB    1 
ATOM   2185 C  CG    . PHE A 1 274 ? 12.27115  8.37419  52.34882 1.000 46.16983  ? 272 PHE A CG    1 
ATOM   2186 C  CD1   . PHE A 1 274 ? 11.34927  8.34970  53.38096 1.000 46.09813  ? 272 PHE A CD1   1 
ATOM   2187 C  CD2   . PHE A 1 274 ? 13.61815  8.36648  52.65874 1.000 43.54141  ? 272 PHE A CD2   1 
ATOM   2188 C  CE1   . PHE A 1 274 ? 11.76465  8.31916  54.70242 1.000 49.70161  ? 272 PHE A CE1   1 
ATOM   2189 C  CE2   . PHE A 1 274 ? 14.04599  8.33423  53.98383 1.000 46.25467  ? 272 PHE A CE2   1 
ATOM   2190 C  CZ    . PHE A 1 274 ? 13.11608  8.31683  55.00093 1.000 50.98148  ? 272 PHE A CZ    1 
ATOM   2191 N  N     . ALA A 1 275 ? 11.83622  10.24287 48.06813 1.000 38.18598  ? 273 ALA A N     1 
ATOM   2192 C  CA    . ALA A 1 275 ? 11.65793  10.01818 46.64358 1.000 39.85114  ? 273 ALA A CA    1 
ATOM   2193 C  C     . ALA A 1 275 ? 12.32534  8.69517  46.27966 1.000 45.63949  ? 273 ALA A C     1 
ATOM   2194 O  O     . ALA A 1 275 ? 13.16997  8.17697  47.02482 1.000 46.77838  ? 273 ALA A O     1 
ATOM   2195 C  CB    . ALA A 1 275 ? 12.23188  11.16777 45.83278 1.000 35.75277  ? 273 ALA A CB    1 
ATOM   2196 O  OXT   . ALA A 1 275 ? 12.02448  8.10349  45.24312 1.000 45.90967  ? 273 ALA A OXT   1 
ATOM   2197 O  "O5'" . DA  B 2 1   ? -13.37601 16.88700 23.95398 1.000 51.63968  ? 1   DA  B "O5'" 1 
ATOM   2198 C  "C5'" . DA  B 2 1   ? -14.71533 17.25755 23.66941 1.000 49.53269  ? 1   DA  B "C5'" 1 
ATOM   2199 C  "C4'" . DA  B 2 1   ? -15.16489 18.39201 24.57370 1.000 46.70874  ? 1   DA  B "C4'" 1 
ATOM   2200 O  "O4'" . DA  B 2 1   ? -15.50178 17.87484 25.88496 1.000 47.94633  ? 1   DA  B "O4'" 1 
ATOM   2201 C  "C3'" . DA  B 2 1   ? -14.14877 19.50529 24.81309 1.000 47.07338  ? 1   DA  B "C3'" 1 
ATOM   2202 O  "O3'" . DA  B 2 1   ? -14.85304 20.72477 24.94516 1.000 43.16870  ? 1   DA  B "O3'" 1 
ATOM   2203 C  "C2'" . DA  B 2 1   ? -13.49460 19.08300 26.12772 1.000 47.67274  ? 1   DA  B "C2'" 1 
ATOM   2204 C  "C1'" . DA  B 2 1   ? -14.67838 18.47102 26.87152 1.000 47.98005  ? 1   DA  B "C1'" 1 
ATOM   2205 N  N9    . DA  B 2 1   ? -14.32005 17.43315 27.84143 1.000 52.66894  ? 1   DA  B N9    1 
ATOM   2206 C  C8    . DA  B 2 1   ? -14.46634 17.49272 29.20536 1.000 55.53514  ? 1   DA  B C8    1 
ATOM   2207 N  N7    . DA  B 2 1   ? -14.07376 16.40337 29.83018 1.000 56.04639  ? 1   DA  B N7    1 
ATOM   2208 C  C5    . DA  B 2 1   ? -13.65566 15.56467 28.80609 1.000 57.09098  ? 1   DA  B C5    1 
ATOM   2209 C  C6    . DA  B 2 1   ? -13.14124 14.25688 28.80648 1.000 60.84049  ? 1   DA  B C6    1 
ATOM   2210 N  N6    . DA  B 2 1   ? -12.94919 13.54720 29.91778 1.000 64.28255  ? 1   DA  B N6    1 
ATOM   2211 N  N1    . DA  B 2 1   ? -12.82844 13.70484 27.61384 1.000 61.44345  ? 1   DA  B N1    1 
ATOM   2212 C  C2    . DA  B 2 1   ? -13.01888 14.42227 26.49814 1.000 58.59925  ? 1   DA  B C2    1 
ATOM   2213 N  N3    . DA  B 2 1   ? -13.49852 15.65855 26.36938 1.000 54.97226  ? 1   DA  B N3    1 
ATOM   2214 C  C4    . DA  B 2 1   ? -13.80497 16.17952 27.57307 1.000 57.59045  ? 1   DA  B C4    1 
ATOM   2215 P  P     . DA  B 2 2   ? -14.08881 22.12777 25.08364 1.000 45.65905  ? 2   DA  B P     1 
ATOM   2216 O  OP1   . DA  B 2 2   ? -15.10096 23.18060 24.83257 1.000 48.08040  ? 2   DA  B OP1   1 
ATOM   2217 O  OP2   . DA  B 2 2   ? -12.85058 22.10139 24.27508 1.000 43.72468  ? 2   DA  B OP2   1 
ATOM   2218 O  "O5'" . DA  B 2 2   ? -13.70674 22.21202 26.63537 1.000 43.15648  ? 2   DA  B "O5'" 1 
ATOM   2219 C  "C5'" . DA  B 2 2   ? -14.73984 22.31856 27.58516 1.000 42.34810  ? 2   DA  B "C5'" 1 
ATOM   2220 C  "C4'" . DA  B 2 2   ? -14.19784 22.47982 28.99728 1.000 47.02407  ? 2   DA  B "C4'" 1 
ATOM   2221 O  "O4'" . DA  B 2 2   ? -13.46944 21.30196 29.39851 1.000 49.36109  ? 2   DA  B "O4'" 1 
ATOM   2222 C  "C3'" . DA  B 2 2   ? -13.26572 23.65244 29.22886 1.000 45.06156  ? 2   DA  B "C3'" 1 
ATOM   2223 O  "O3'" . DA  B 2 2   ? -13.51412 24.17695 30.53973 1.000 54.26027  ? 2   DA  B "O3'" 1 
ATOM   2224 C  "C2'" . DA  B 2 2   ? -11.85614 23.03324 29.10010 1.000 47.88251  ? 2   DA  B "C2'" 1 
ATOM   2225 C  "C1'" . DA  B 2 2   ? -12.08185 21.57276 29.51537 1.000 49.36904  ? 2   DA  B "C1'" 1 
ATOM   2226 N  N9    . DA  B 2 2   ? -11.39716 20.58677 28.67451 1.000 50.63210  ? 2   DA  B N9    1 
ATOM   2227 C  C8    . DA  B 2 2   ? -10.93919 20.75526 27.39518 1.000 54.55744  ? 2   DA  B C8    1 
ATOM   2228 N  N7    . DA  B 2 2   ? -10.40051 19.66940 26.88068 1.000 51.97723  ? 2   DA  B N7    1 
ATOM   2229 C  C5    . DA  B 2 2   ? -10.54287 18.71812 27.88575 1.000 53.86154  ? 2   DA  B C5    1 
ATOM   2230 C  C6    . DA  B 2 2   ? -10.17857 17.35871 27.97158 1.000 56.77445  ? 2   DA  B C6    1 
ATOM   2231 N  N6    . DA  B 2 2   ? -9.57407  16.69587 26.98160 1.000 58.21495  ? 2   DA  B N6    1 
ATOM   2232 N  N1    . DA  B 2 2   ? -10.45526 16.70511 29.11917 1.000 58.71939  ? 2   DA  B N1    1 
ATOM   2233 C  C2    . DA  B 2 2   ? -11.04895 17.36873 30.11108 1.000 57.89584  ? 2   DA  B C2    1 
ATOM   2234 N  N3    . DA  B 2 2   ? -11.43871 18.63859 30.14923 1.000 55.20876  ? 2   DA  B N3    1 
ATOM   2235 C  C4    . DA  B 2 2   ? -11.15635 19.26494 28.99239 1.000 53.17100  ? 2   DA  B C4    1 
ATOM   2236 P  P     . DG  B 2 3   ? -12.66254 25.41568 31.10720 1.000 52.13125  ? 3   DG  B P     1 
ATOM   2237 O  OP1   . DG  B 2 3   ? -13.52749 26.14676 32.05091 1.000 54.78696  ? 3   DG  B OP1   1 
ATOM   2238 O  OP2   . DG  B 2 3   ? -11.96941 26.10454 29.99632 1.000 61.25099  ? 3   DG  B OP2   1 
ATOM   2239 O  "O5'" . DG  B 2 3   ? -11.48541 24.72497 31.93168 1.000 53.10591  ? 3   DG  B "O5'" 1 
ATOM   2240 C  "C5'" . DG  B 2 3   ? -11.78896 23.77345 32.92713 1.000 48.50548  ? 3   DG  B "C5'" 1 
ATOM   2241 C  "C4'" . DG  B 2 3   ? -10.52584 23.05172 33.34680 1.000 47.79265  ? 3   DG  B "C4'" 1 
ATOM   2242 O  "O4'" . DG  B 2 3   ? -10.15506 22.07274 32.33709 1.000 47.09326  ? 3   DG  B "O4'" 1 
ATOM   2243 C  "C3'" . DG  B 2 3   ? -9.28224  23.93801 33.51793 1.000 51.31199  ? 3   DG  B "C3'" 1 
ATOM   2244 O  "O3'" . DG  B 2 3   ? -8.53081  23.43066 34.58231 1.000 59.42681  ? 3   DG  B "O3'" 1 
ATOM   2245 C  "C2'" . DG  B 2 3   ? -8.54567  23.70492 32.20560 1.000 49.18128  ? 3   DG  B "C2'" 1 
ATOM   2246 C  "C1'" . DG  B 2 3   ? -8.78227  22.22010 32.08713 1.000 42.88341  ? 3   DG  B "C1'" 1 
ATOM   2247 N  N9    . DG  B 2 3   ? -8.44339  21.63893 30.79860 1.000 42.12028  ? 3   DG  B N9    1 
ATOM   2248 C  C8    . DG  B 2 3   ? -8.41274  22.25946 29.57633 1.000 43.01838  ? 3   DG  B C8    1 
ATOM   2249 N  N7    . DG  B 2 3   ? -8.05438  21.45952 28.60078 1.000 40.51721  ? 3   DG  B N7    1 
ATOM   2250 C  C5    . DG  B 2 3   ? -7.82438  20.24195 29.23192 1.000 39.55981  ? 3   DG  B C5    1 
ATOM   2251 C  C6    . DG  B 2 3   ? -7.39489  19.00233 28.69643 1.000 34.58496  ? 3   DG  B C6    1 
ATOM   2252 O  O6    . DG  B 2 3   ? -7.16387  18.72420 27.51148 1.000 42.14642  ? 3   DG  B O6    1 
ATOM   2253 N  N1    . DG  B 2 3   ? -7.29254  18.02180 29.68259 1.000 33.31194  ? 3   DG  B N1    1 
ATOM   2254 C  C2    . DG  B 2 3   ? -7.55326  18.22441 31.02473 1.000 41.75685  ? 3   DG  B C2    1 
ATOM   2255 N  N2    . DG  B 2 3   ? -7.39494  17.16642 31.83950 1.000 39.02397  ? 3   DG  B N2    1 
ATOM   2256 N  N3    . DG  B 2 3   ? -7.94945  19.38549 31.53461 1.000 40.19274  ? 3   DG  B N3    1 
ATOM   2257 C  C4    . DG  B 2 3   ? -8.06421  20.34069 30.58095 1.000 38.20197  ? 3   DG  B C4    1 
ATOM   2258 P  P     . DA  B 2 4   ? -7.61786  24.38124 35.49860 1.000 56.59431  ? 4   DA  B P     1 
ATOM   2259 O  OP1   . DA  B 2 4   ? -8.50289  24.92521 36.51840 1.000 48.11457  ? 4   DA  B OP1   1 
ATOM   2260 O  OP2   . DA  B 2 4   ? -6.74835  25.24645 34.66830 1.000 50.46780  ? 4   DA  B OP2   1 
ATOM   2261 O  "O5'" . DA  B 2 4   ? -6.64899  23.33773 36.21108 1.000 47.61037  ? 4   DA  B "O5'" 1 
ATOM   2262 C  "C5'" . DA  B 2 4   ? -7.21430  22.22866 36.90769 1.000 38.72731  ? 4   DA  B "C5'" 1 
ATOM   2263 C  "C4'" . DA  B 2 4   ? -6.20242  21.10262 36.92936 1.000 37.42584  ? 4   DA  B "C4'" 1 
ATOM   2264 O  "O4'" . DA  B 2 4   ? -6.12495  20.50449 35.60295 1.000 35.14434  ? 4   DA  B "O4'" 1 
ATOM   2265 C  "C3'" . DA  B 2 4   ? -4.77824  21.53186 37.28389 1.000 37.24118  ? 4   DA  B "C3'" 1 
ATOM   2266 O  "O3'" . DA  B 2 4   ? -4.16647  20.51120 38.05366 1.000 36.16054  ? 4   DA  B "O3'" 1 
ATOM   2267 C  "C2'" . DA  B 2 4   ? -4.11933  21.66874 35.91422 1.000 32.87663  ? 4   DA  B "C2'" 1 
ATOM   2268 C  "C1'" . DA  B 2 4   ? -4.79242  20.54026 35.15222 1.000 31.23704  ? 4   DA  B "C1'" 1 
ATOM   2269 N  N9    . DA  B 2 4   ? -4.80827  20.75246 33.70659 1.000 33.70006  ? 4   DA  B N9    1 
ATOM   2270 C  C8    . DA  B 2 4   ? -5.14532  21.90278 33.04291 1.000 35.14445  ? 4   DA  B C8    1 
ATOM   2271 N  N7    . DA  B 2 4   ? -5.07596  21.79328 31.73243 1.000 30.44859  ? 4   DA  B N7    1 
ATOM   2272 C  C5    . DA  B 2 4   ? -4.66811  20.48278 31.52739 1.000 28.37189  ? 4   DA  B C5    1 
ATOM   2273 C  C6    . DA  B 2 4   ? -4.39069  19.74298 30.34729 1.000 26.22843  ? 4   DA  B C6    1 
ATOM   2274 N  N6    . DA  B 2 4   ? -4.49473  20.25452 29.11947 1.000 26.35805  ? 4   DA  B N6    1 
ATOM   2275 N  N1    . DA  B 2 4   ? -4.00575  18.46144 30.49366 1.000 29.53123  ? 4   DA  B N1    1 
ATOM   2276 C  C2    . DA  B 2 4   ? -3.88219  17.95866 31.73085 1.000 33.17078  ? 4   DA  B C2    1 
ATOM   2277 N  N3    . DA  B 2 4   ? -4.10888  18.55725 32.90607 1.000 29.14128  ? 4   DA  B N3    1 
ATOM   2278 C  C4    . DA  B 2 4   ? -4.49103  19.82940 32.73015 1.000 29.48393  ? 4   DA  B C4    1 
ATOM   2279 P  P     . DC  B 2 5   ? -2.81859  20.78178 38.89445 1.000 34.68623  ? 5   DC  B P     1 
ATOM   2280 O  OP1   . DC  B 2 5   ? -2.93737  19.80558 40.01513 1.000 39.91300  ? 5   DC  B OP1   1 
ATOM   2281 O  OP2   . DC  B 2 5   ? -2.64012  22.22329 39.19987 1.000 35.93253  ? 5   DC  B OP2   1 
ATOM   2282 O  "O5'" . DC  B 2 5   ? -1.63026  20.45720 37.85491 1.000 31.29308  ? 5   DC  B "O5'" 1 
ATOM   2283 C  "C5'" . DC  B 2 5   ? -1.27981  19.13358 37.57839 1.000 28.96134  ? 5   DC  B "C5'" 1 
ATOM   2284 C  "C4'" . DC  B 2 5   ? -0.28771  19.07889 36.45070 1.000 24.61385  ? 5   DC  B "C4'" 1 
ATOM   2285 O  "O4'" . DC  B 2 5   ? -0.96054  19.40175 35.20787 1.000 26.07698  ? 5   DC  B "O4'" 1 
ATOM   2286 C  "C3'" . DC  B 2 5   ? 0.87969   20.07583 36.57107 1.000 24.41745  ? 5   DC  B "C3'" 1 
ATOM   2287 O  "O3'" . DC  B 2 5   ? 2.11075   19.37836 36.34878 1.000 24.20330  ? 5   DC  B "O3'" 1 
ATOM   2288 C  "C2'" . DC  B 2 5   ? 0.59494   21.06713 35.42895 1.000 26.45896  ? 5   DC  B "C2'" 1 
ATOM   2289 C  "C1'" . DC  B 2 5   ? -0.04444  20.11037 34.44133 1.000 24.72473  ? 5   DC  B "C1'" 1 
ATOM   2290 N  N1    . DC  B 2 5   ? -0.71656  20.74531 33.28158 1.000 24.89440  ? 5   DC  B N1    1 
ATOM   2291 C  C2    . DC  B 2 5   ? -0.69552  20.07279 32.06367 1.000 25.14896  ? 5   DC  B C2    1 
ATOM   2292 O  O2    . DC  B 2 5   ? -0.20391  18.94838 32.01556 1.000 23.49510  ? 5   DC  B O2    1 
ATOM   2293 N  N3    . DC  B 2 5   ? -1.25711  20.64578 30.98828 1.000 22.58925  ? 5   DC  B N3    1 
ATOM   2294 C  C4    . DC  B 2 5   ? -1.79424  21.85177 31.07014 1.000 27.24037  ? 5   DC  B C4    1 
ATOM   2295 N  N4    . DC  B 2 5   ? -2.31297  22.36366 29.95689 1.000 28.30228  ? 5   DC  B N4    1 
ATOM   2296 C  C5    . DC  B 2 5   ? -1.84235  22.57881 32.30829 1.000 26.34761  ? 5   DC  B C5    1 
ATOM   2297 C  C6    . DC  B 2 5   ? -1.27041  21.99360 33.38877 1.000 27.35013  ? 5   DC  B C6    1 
HETATM 2298 P  P     . 8OG B 2 6   ? 3.48823   19.94935 36.92493 1.000 25.54119  ? 6   8OG B P     1 
HETATM 2299 O  OP1   . 8OG B 2 6   ? 4.52695   18.95473 36.42863 1.000 25.10965  ? 6   8OG B OP1   1 
HETATM 2300 O  OP2   . 8OG B 2 6   ? 3.38964   20.20177 38.39829 1.000 25.69776  ? 6   8OG B OP2   1 
HETATM 2301 O  "O5'" . 8OG B 2 6   ? 3.64146   21.34099 36.11782 1.000 23.79672  ? 6   8OG B "O5'" 1 
HETATM 2302 C  "C5'" . 8OG B 2 6   ? 4.57226   22.31065 36.60982 1.000 23.01421  ? 6   8OG B "C5'" 1 
HETATM 2303 C  "C4'" . 8OG B 2 6   ? 5.96920   22.05268 36.01526 1.000 23.20512  ? 6   8OG B "C4'" 1 
HETATM 2304 O  "O4'" . 8OG B 2 6   ? 5.94111   22.01513 34.59051 1.000 23.18928  ? 6   8OG B "O4'" 1 
HETATM 2305 C  "C3'" . 8OG B 2 6   ? 6.95616   23.14599 36.37700 1.000 23.20482  ? 6   8OG B "C3'" 1 
HETATM 2306 O  "O3'" . 8OG B 2 6   ? 8.24718   22.51430 36.36215 1.000 23.50015  ? 6   8OG B "O3'" 1 
HETATM 2307 C  "C2'" . 8OG B 2 6   ? 6.79726   24.12406 35.22201 1.000 23.15033  ? 6   8OG B "C2'" 1 
HETATM 2308 C  "C1'" . 8OG B 2 6   ? 6.59407   23.16543 34.05562 1.000 22.35624  ? 6   8OG B "C1'" 1 
HETATM 2309 N  N9    . 8OG B 2 6   ? 5.68444   23.62787 32.99780 1.000 22.70941  ? 6   8OG B N9    1 
HETATM 2310 C  C8    . 8OG B 2 6   ? 4.54211   24.31541 33.02523 1.000 24.37447  ? 6   8OG B C8    1 
HETATM 2311 N  N7    . 8OG B 2 6   ? 3.93944   24.53303 31.84141 1.000 21.73275  ? 6   8OG B N7    1 
HETATM 2312 C  C5    . 8OG B 2 6   ? 4.76160   23.89929 30.97680 1.000 21.95005  ? 6   8OG B C5    1 
HETATM 2313 C  C6    . 8OG B 2 6   ? 4.78771   23.67848 29.52891 1.000 22.11693  ? 6   8OG B C6    1 
HETATM 2314 O  O6    . 8OG B 2 6   ? 3.88396   24.13148 28.77316 1.000 22.34919  ? 6   8OG B O6    1 
HETATM 2315 N  N1    . 8OG B 2 6   ? 5.81641   22.96662 29.03594 1.000 20.81593  ? 6   8OG B N1    1 
HETATM 2316 C  C2    . 8OG B 2 6   ? 6.81958   22.47088 29.80239 1.000 21.37812  ? 6   8OG B C2    1 
HETATM 2317 N  N2    . 8OG B 2 6   ? 7.82121   21.75534 29.23451 1.000 21.21747  ? 6   8OG B N2    1 
HETATM 2318 N  N3    . 8OG B 2 6   ? 6.86070   22.63524 31.14087 1.000 19.71931  ? 6   8OG B N3    1 
HETATM 2319 C  C4    . 8OG B 2 6   ? 5.87365   23.31831 31.73397 1.000 22.75933  ? 6   8OG B C4    1 
HETATM 2320 O  O8    . 8OG B 2 6   ? 4.03893   24.76023 34.10937 1.000 24.54119  ? 6   8OG B O8    1 
ATOM   2321 P  P     . DT  B 2 7   ? 9.56995   23.27028 36.87237 1.000 25.41817  ? 7   DT  B P     1 
ATOM   2322 O  OP1   . DT  B 2 7   ? 10.58167  22.20934 37.06537 1.000 27.09850  ? 7   DT  B OP1   1 
ATOM   2323 O  OP2   . DT  B 2 7   ? 9.20592   24.19987 37.97536 1.000 27.90825  ? 7   DT  B OP2   1 
ATOM   2324 O  "O5'" . DT  B 2 7   ? 10.00660  24.21160 35.66089 1.000 25.34226  ? 7   DT  B "O5'" 1 
ATOM   2325 C  "C5'" . DT  B 2 7   ? 10.73732  23.65670 34.56835 1.000 26.33609  ? 7   DT  B "C5'" 1 
ATOM   2326 C  "C4'" . DT  B 2 7   ? 10.89617  24.69640 33.48526 1.000 25.45814  ? 7   DT  B "C4'" 1 
ATOM   2327 O  "O4'" . DT  B 2 7   ? 9.63982   24.82906 32.77431 1.000 26.26712  ? 7   DT  B "O4'" 1 
ATOM   2328 C  "C3'" . DT  B 2 7   ? 11.22248  26.11768 34.00243 1.000 26.46736  ? 7   DT  B "C3'" 1 
ATOM   2329 O  "O3'" . DT  B 2 7   ? 12.28025  26.67862 33.25072 1.000 29.24968  ? 7   DT  B "O3'" 1 
ATOM   2330 C  "C2'" . DT  B 2 7   ? 9.92469   26.87903 33.74997 1.000 25.14580  ? 7   DT  B "C2'" 1 
ATOM   2331 C  "C1'" . DT  B 2 7   ? 9.50809   26.18672 32.47764 1.000 26.28888  ? 7   DT  B "C1'" 1 
ATOM   2332 N  N1    . DT  B 2 7   ? 8.14807   26.51577 31.93893 1.000 25.61880  ? 7   DT  B N1    1 
ATOM   2333 C  C2    . DT  B 2 7   ? 7.93386   26.30211 30.58923 1.000 24.65784  ? 7   DT  B C2    1 
ATOM   2334 O  O2    . DT  B 2 7   ? 8.77519   25.79428 29.86463 1.000 24.53708  ? 7   DT  B O2    1 
ATOM   2335 N  N3    . DT  B 2 7   ? 6.69617   26.64814 30.13138 1.000 22.05506  ? 7   DT  B N3    1 
ATOM   2336 C  C4    . DT  B 2 7   ? 5.66905   27.22095 30.84954 1.000 24.34898  ? 7   DT  B C4    1 
ATOM   2337 O  O4    . DT  B 2 7   ? 4.59945   27.51002 30.33659 1.000 25.94182  ? 7   DT  B O4    1 
ATOM   2338 C  C5    . DT  B 2 7   ? 5.94506   27.44556 32.25522 1.000 25.89399  ? 7   DT  B C5    1 
ATOM   2339 C  C7    . DT  B 2 7   ? 4.88795   28.06266 33.11861 1.000 26.01426  ? 7   DT  B C7    1 
ATOM   2340 C  C6    . DT  B 2 7   ? 7.16630   27.10127 32.73754 1.000 27.10132  ? 7   DT  B C6    1 
ATOM   2341 P  P     . DG  B 2 8   ? 13.80020  26.61209 33.78152 1.000 29.03589  ? 8   DG  B P     1 
ATOM   2342 O  OP1   . DG  B 2 8   ? 13.98708  25.33180 34.49098 1.000 26.98062  ? 8   DG  B OP1   1 
ATOM   2343 O  OP2   . DG  B 2 8   ? 14.15364  27.88758 34.45166 1.000 35.57521  ? 8   DG  B OP2   1 
ATOM   2344 O  "O5'" . DG  B 2 8   ? 14.63754  26.59473 32.41657 1.000 29.09385  ? 8   DG  B "O5'" 1 
ATOM   2345 C  "C5'" . DG  B 2 8   ? 14.55543  25.47077 31.56132 1.000 29.23516  ? 8   DG  B "C5'" 1 
ATOM   2346 C  "C4'" . DG  B 2 8   ? 14.38593  25.91924 30.12553 1.000 30.41422  ? 8   DG  B "C4'" 1 
ATOM   2347 O  "O4'" . DG  B 2 8   ? 13.00585  26.33901 29.90522 1.000 26.99710  ? 8   DG  B "O4'" 1 
ATOM   2348 C  "C3'" . DG  B 2 8   ? 15.25337  27.10037 29.69968 1.000 28.71558  ? 8   DG  B "C3'" 1 
ATOM   2349 O  "O3'" . DG  B 2 8   ? 15.58426  26.92930 28.36136 1.000 32.04258  ? 8   DG  B "O3'" 1 
ATOM   2350 C  "C2'" . DG  B 2 8   ? 14.29728  28.27827 29.84795 1.000 31.00508  ? 8   DG  B "C2'" 1 
ATOM   2351 C  "C1'" . DG  B 2 8   ? 13.00650  27.63568 29.35224 1.000 26.14735  ? 8   DG  B "C1'" 1 
ATOM   2352 N  N9    . DG  B 2 8   ? 11.78556  28.30365 29.77496 1.000 28.58052  ? 8   DG  B N9    1 
ATOM   2353 C  C8    . DG  B 2 8   ? 11.48672  28.83221 31.01583 1.000 28.98042  ? 8   DG  B C8    1 
ATOM   2354 N  N7    . DG  B 2 8   ? 10.27853  29.34187 31.08253 1.000 28.71209  ? 8   DG  B N7    1 
ATOM   2355 C  C5    . DG  B 2 8   ? 9.75168   29.12788 29.80608 1.000 25.77965  ? 8   DG  B C5    1 
ATOM   2356 C  C6    . DG  B 2 8   ? 8.48004   29.45135 29.26117 1.000 25.96477  ? 8   DG  B C6    1 
ATOM   2357 O  O6    . DG  B 2 8   ? 7.52741   30.03140 29.80658 1.000 28.54206  ? 8   DG  B O6    1 
ATOM   2358 N  N1    . DG  B 2 8   ? 8.37143   29.05150 27.92839 1.000 24.15297  ? 8   DG  B N1    1 
ATOM   2359 C  C2    . DG  B 2 8   ? 9.34703   28.40527 27.21687 1.000 26.73421  ? 8   DG  B C2    1 
ATOM   2360 N  N2    . DG  B 2 8   ? 9.05687   28.11399 25.93211 1.000 25.12414  ? 8   DG  B N2    1 
ATOM   2361 N  N3    . DG  B 2 8   ? 10.53304  28.09668 27.70761 1.000 25.84179  ? 8   DG  B N3    1 
ATOM   2362 C  C4    . DG  B 2 8   ? 10.66758  28.48525 29.00361 1.000 25.47250  ? 8   DG  B C4    1 
ATOM   2363 P  P     . DG  B 2 9   ? 17.06533  27.15242 27.79825 1.000 34.13157  ? 9   DG  B P     1 
ATOM   2364 O  OP1   . DG  B 2 9   ? 17.67931  25.81725 27.89202 1.000 40.84833  ? 9   DG  B OP1   1 
ATOM   2365 O  OP2   . DG  B 2 9   ? 17.75897  28.31485 28.40245 1.000 38.10801  ? 9   DG  B OP2   1 
ATOM   2366 O  "O5'" . DG  B 2 9   ? 16.77430  27.54081 26.27751 1.000 37.81612  ? 9   DG  B "O5'" 1 
ATOM   2367 C  "C5'" . DG  B 2 9   ? 16.16925  26.59306 25.41980 1.000 36.77393  ? 9   DG  B "C5'" 1 
ATOM   2368 C  "C4'" . DG  B 2 9   ? 15.38497  27.26518 24.29995 1.000 36.45147  ? 9   DG  B "C4'" 1 
ATOM   2369 O  "O4'" . DG  B 2 9   ? 14.14527  27.81423 24.81598 1.000 36.93217  ? 9   DG  B "O4'" 1 
ATOM   2370 C  "C3'" . DG  B 2 9   ? 16.09225  28.39947 23.55884 1.000 41.77659  ? 9   DG  B "C3'" 1 
ATOM   2371 O  "O3'" . DG  B 2 9   ? 15.94604  28.17311 22.17882 1.000 44.00946  ? 9   DG  B "O3'" 1 
ATOM   2372 C  "C2'" . DG  B 2 9   ? 15.33914  29.65494 24.00944 1.000 41.28628  ? 9   DG  B "C2'" 1 
ATOM   2373 C  "C1'" . DG  B 2 9   ? 13.94682  29.10634 24.30086 1.000 35.70121  ? 9   DG  B "C1'" 1 
ATOM   2374 N  N9    . DG  B 2 9   ? 13.21693  29.84259 25.32789 1.000 38.35417  ? 9   DG  B N9    1 
ATOM   2375 C  C8    . DG  B 2 9   ? 13.63582  30.09854 26.60947 1.000 37.19362  ? 9   DG  B C8    1 
ATOM   2376 N  N7    . DG  B 2 9   ? 12.76452  30.75422 27.32023 1.000 31.54561  ? 9   DG  B N7    1 
ATOM   2377 C  C5    . DG  B 2 9   ? 11.68317  30.92240 26.46244 1.000 31.88712  ? 9   DG  B C5    1 
ATOM   2378 C  C6    . DG  B 2 9   ? 10.44330  31.56288 26.68637 1.000 32.02621  ? 9   DG  B C6    1 
ATOM   2379 O  O6    . DG  B 2 9   ? 10.04682  32.10272 27.73565 1.000 32.93937  ? 9   DG  B O6    1 
ATOM   2380 N  N1    . DG  B 2 9   ? 9.62627   31.51970 25.55433 1.000 31.94954  ? 9   DG  B N1    1 
ATOM   2381 C  C2    . DG  B 2 9   ? 9.97463   30.93311 24.35704 1.000 34.20867  ? 9   DG  B C2    1 
ATOM   2382 N  N2    . DG  B 2 9   ? 9.06035   30.98360 23.36815 1.000 32.01647  ? 9   DG  B N2    1 
ATOM   2383 N  N3    . DG  B 2 9   ? 11.14272  30.33186 24.14157 1.000 34.44122  ? 9   DG  B N3    1 
ATOM   2384 C  C4    . DG  B 2 9   ? 11.93900  30.36243 25.23330 1.000 35.14068  ? 9   DG  B C4    1 
ATOM   2385 P  P     . DA  B 2 10  ? 16.64990  29.12258 21.08511 1.000 42.20513  ? 10  DA  B P     1 
ATOM   2386 O  OP1   . DA  B 2 10  ? 17.01106  28.20815 19.97016 1.000 44.67081  ? 10  DA  B OP1   1 
ATOM   2387 O  OP2   . DA  B 2 10  ? 17.65555  29.98378 21.73708 1.000 44.48080  ? 10  DA  B OP2   1 
ATOM   2388 O  "O5'" . DA  B 2 10  ? 15.46814  30.09599 20.60799 1.000 40.18435  ? 10  DA  B "O5'" 1 
ATOM   2389 C  "C5'" . DA  B 2 10  ? 14.29074  29.56417 20.07344 1.000 39.92675  ? 10  DA  B "C5'" 1 
ATOM   2390 C  "C4'" . DA  B 2 10  ? 13.38027  30.67772 19.58946 1.000 44.76556  ? 10  DA  B "C4'" 1 
ATOM   2391 O  "O4'" . DA  B 2 10  ? 12.65076  31.23790 20.71572 1.000 40.29715  ? 10  DA  B "O4'" 1 
ATOM   2392 C  "C3'" . DA  B 2 10  ? 14.09314  31.85131 18.92075 1.000 43.26149  ? 10  DA  B "C3'" 1 
ATOM   2393 O  "O3'" . DA  B 2 10  ? 13.34038  32.28486 17.79758 1.000 56.01580  ? 10  DA  B "O3'" 1 
ATOM   2394 C  "C2'" . DA  B 2 10  ? 14.13155  32.91131 20.02104 1.000 43.97944  ? 10  DA  B "C2'" 1 
ATOM   2395 C  "C1'" . DA  B 2 10  ? 12.82649  32.63476 20.75216 1.000 41.81318  ? 10  DA  B "C1'" 1 
ATOM   2396 N  N9    . DA  B 2 10  ? 12.83335  33.03901 22.15242 1.000 38.66291  ? 10  DA  B N9    1 
ATOM   2397 C  C8    . DA  B 2 10  ? 13.84728  32.86712 23.05505 1.000 37.31946  ? 10  DA  B C8    1 
ATOM   2398 N  N7    . DA  B 2 10  ? 13.56520  33.30792 24.25324 1.000 35.29647  ? 10  DA  B N7    1 
ATOM   2399 C  C5    . DA  B 2 10  ? 12.27354  33.79473 24.13576 1.000 33.43987  ? 10  DA  B C5    1 
ATOM   2400 C  C6    . DA  B 2 10  ? 11.39954  34.39638 25.06925 1.000 36.87627  ? 10  DA  B C6    1 
ATOM   2401 N  N6    . DA  B 2 10  ? 11.72794  34.61706 26.34424 1.000 35.29018  ? 10  DA  B N6    1 
ATOM   2402 N  N1    . DA  B 2 10  ? 10.17008  34.76579 24.62827 1.000 34.96248  ? 10  DA  B N1    1 
ATOM   2403 C  C2    . DA  B 2 10  ? 9.85426   34.54487 23.33900 1.000 35.21512  ? 10  DA  B C2    1 
ATOM   2404 N  N3    . DA  B 2 10  ? 10.59339  33.98575 22.37318 1.000 34.97459  ? 10  DA  B N3    1 
ATOM   2405 C  C4    . DA  B 2 10  ? 11.80380  33.63283 22.84678 1.000 36.26181  ? 10  DA  B C4    1 
ATOM   2406 P  P     . DC  B 2 11  ? 13.96240  33.34537 16.76088 1.000 57.76024  ? 11  DC  B P     1 
ATOM   2407 O  OP1   . DC  B 2 11  ? 13.64070  32.84981 15.40880 1.000 61.67718  ? 11  DC  B OP1   1 
ATOM   2408 O  OP2   . DC  B 2 11  ? 15.36066  33.64502 17.16093 1.000 55.77825  ? 11  DC  B OP2   1 
ATOM   2409 O  "O5'" . DC  B 2 11  ? 13.13108  34.67836 17.05561 1.000 50.52896  ? 11  DC  B "O5'" 1 
ATOM   2410 C  "C5'" . DC  B 2 11  ? 11.72435  34.62216 17.16215 1.000 45.11191  ? 11  DC  B "C5'" 1 
ATOM   2411 C  "C4'" . DC  B 2 11  ? 11.20812  35.87091 17.83444 1.000 47.82351  ? 11  DC  B "C4'" 1 
ATOM   2412 O  "O4'" . DC  B 2 11  ? 11.41533  35.76900 19.26750 1.000 45.28911  ? 11  DC  B "O4'" 1 
ATOM   2413 C  "C3'" . DC  B 2 11  ? 11.91060  37.16526 17.39712 1.000 50.09396  ? 11  DC  B "C3'" 1 
ATOM   2414 O  "O3'" . DC  B 2 11  ? 10.94504  38.12095 16.98044 1.000 53.05408  ? 11  DC  B "O3'" 1 
ATOM   2415 C  "C2'" . DC  B 2 11  ? 12.65144  37.62354 18.65911 1.000 50.94362  ? 11  DC  B "C2'" 1 
ATOM   2416 C  "C1'" . DC  B 2 11  ? 11.76015  37.03562 19.74334 1.000 45.57191  ? 11  DC  B "C1'" 1 
ATOM   2417 N  N1    . DC  B 2 11  ? 12.41189  36.89202 21.06697 1.000 48.91118  ? 11  DC  B N1    1 
ATOM   2418 C  C2    . DC  B 2 11  ? 11.70531  37.26167 22.21123 1.000 46.73777  ? 11  DC  B C2    1 
ATOM   2419 O  O2    . DC  B 2 11  ? 10.54893  37.69011 22.08730 1.000 43.70194  ? 11  DC  B O2    1 
ATOM   2420 N  N3    . DC  B 2 11  ? 12.30393  37.13838 23.42536 1.000 45.95367  ? 11  DC  B N3    1 
ATOM   2421 C  C4    . DC  B 2 11  ? 13.55008  36.67006 23.51263 1.000 48.00101  ? 11  DC  B C4    1 
ATOM   2422 N  N4    . DC  B 2 11  ? 14.09411  36.56352 24.73011 1.000 47.49458  ? 11  DC  B N4    1 
ATOM   2423 C  C5    . DC  B 2 11  ? 14.29220  36.28992 22.35030 1.000 48.40485  ? 11  DC  B C5    1 
ATOM   2424 C  C6    . DC  B 2 11  ? 13.68823  36.41428 21.16022 1.000 48.66118  ? 11  DC  B C6    1 
ATOM   2425 O  "O5'" . DT  C 3 1   ? 9.97245   45.43147 27.31975 1.000 118.73089 ? 1   DT  C "O5'" 1 
ATOM   2426 C  "C5'" . DT  C 3 1   ? 10.35191  44.25339 26.61428 1.000 110.38909 ? 1   DT  C "C5'" 1 
ATOM   2427 C  "C4'" . DT  C 3 1   ? 10.83745  43.17834 27.57221 1.000 99.57955  ? 1   DT  C "C4'" 1 
ATOM   2428 O  "O4'" . DT  C 3 1   ? 11.21545  42.00992 26.81825 1.000 90.72601  ? 1   DT  C "O4'" 1 
ATOM   2429 C  "C3'" . DT  C 3 1   ? 12.08075  43.54535 28.36624 1.000 110.27602 ? 1   DT  C "C3'" 1 
ATOM   2430 O  "O3'" . DT  C 3 1   ? 11.72194  44.23955 29.59225 1.000 115.44826 ? 1   DT  C "O3'" 1 
ATOM   2431 C  "C2'" . DT  C 3 1   ? 12.75336  42.19225 28.63436 1.000 99.83783  ? 1   DT  C "C2'" 1 
ATOM   2432 C  "C1'" . DT  C 3 1   ? 12.17534  41.27132 27.54596 1.000 91.36188  ? 1   DT  C "C1'" 1 
ATOM   2433 N  N1    . DT  C 3 1   ? 13.20359  40.71577 26.58334 1.000 87.08587  ? 1   DT  C N1    1 
ATOM   2434 C  C2    . DT  C 3 1   ? 14.34233  40.11277 27.07952 1.000 87.16228  ? 1   DT  C C2    1 
ATOM   2435 O  O2    . DT  C 3 1   ? 14.58181  40.01046 28.27088 1.000 89.75942  ? 1   DT  C O2    1 
ATOM   2436 N  N3    . DT  C 3 1   ? 15.20402  39.63603 26.12291 1.000 87.12884  ? 1   DT  C N3    1 
ATOM   2437 C  C4    . DT  C 3 1   ? 15.04739  39.69566 24.74887 1.000 87.03523  ? 1   DT  C C4    1 
ATOM   2438 O  O4    . DT  C 3 1   ? 15.88611  39.24033 23.97190 1.000 87.14447  ? 1   DT  C O4    1 
ATOM   2439 C  C5    . DT  C 3 1   ? 13.82788  40.33198 24.29398 1.000 87.07602  ? 1   DT  C C5    1 
ATOM   2440 C  C7    . DT  C 3 1   ? 13.54220  40.45489 22.82624 1.000 87.46051  ? 1   DT  C C7    1 
ATOM   2441 C  C6    . DT  C 3 1   ? 12.97540  40.80270 25.22211 1.000 87.05335  ? 1   DT  C C6    1 
ATOM   2442 P  P     . DG  C 3 2   ? 10.91456  43.50767 30.78336 1.000 107.67084 ? 2   DG  C P     1 
ATOM   2443 O  OP1   . DG  C 3 2   ? 10.63631  44.53552 31.81214 1.000 112.30096 ? 2   DG  C OP1   1 
ATOM   2444 O  OP2   . DG  C 3 2   ? 11.63147  42.27225 31.17593 1.000 98.28102  ? 2   DG  C OP2   1 
ATOM   2445 O  "O5'" . DG  C 3 2   ? 9.50848   43.10927 30.12285 1.000 93.05920  ? 2   DG  C "O5'" 1 
ATOM   2446 C  "C5'" . DG  C 3 2   ? 8.44231   42.63819 30.94446 1.000 80.81513  ? 2   DG  C "C5'" 1 
ATOM   2447 C  "C4'" . DG  C 3 2   ? 7.25051   42.23847 30.09872 1.000 70.94125  ? 2   DG  C "C4'" 1 
ATOM   2448 O  "O4'" . DG  C 3 2   ? 7.72754   41.62503 28.88056 1.000 67.44963  ? 2   DG  C "O4'" 1 
ATOM   2449 C  "C3'" . DG  C 3 2   ? 6.34401   41.19292 30.73069 1.000 59.55835  ? 2   DG  C "C3'" 1 
ATOM   2450 O  "O3'" . DG  C 3 2   ? 5.05544   41.24013 30.14657 1.000 51.14470  ? 2   DG  C "O3'" 1 
ATOM   2451 C  "C2'" . DG  C 3 2   ? 7.05781   39.90435 30.37431 1.000 55.60280  ? 2   DG  C "C2'" 1 
ATOM   2452 C  "C1'" . DG  C 3 2   ? 7.61487   40.21815 28.98609 1.000 57.39404  ? 2   DG  C "C1'" 1 
ATOM   2453 N  N9    . DG  C 3 2   ? 8.92301   39.61903 28.76400 1.000 59.73221  ? 2   DG  C N9    1 
ATOM   2454 C  C8    . DG  C 3 2   ? 9.87570   39.33077 29.71485 1.000 63.99046  ? 2   DG  C C8    1 
ATOM   2455 N  N7    . DG  C 3 2   ? 10.94753  38.77585 29.22286 1.000 64.04913  ? 2   DG  C N7    1 
ATOM   2456 C  C5    . DG  C 3 2   ? 10.68039  38.67684 27.86104 1.000 58.98697  ? 2   DG  C C5    1 
ATOM   2457 C  C6    . DG  C 3 2   ? 11.47488  38.16369 26.81358 1.000 57.24463  ? 2   DG  C C6    1 
ATOM   2458 O  O6    . DG  C 3 2   ? 12.60672  37.66922 26.88175 1.000 55.43133  ? 2   DG  C O6    1 
ATOM   2459 N  N1    . DG  C 3 2   ? 10.83166  38.26651 25.58243 1.000 51.51955  ? 2   DG  C N1    1 
ATOM   2460 C  C2    . DG  C 3 2   ? 9.57682   38.79751 25.39081 1.000 49.95404  ? 2   DG  C C2    1 
ATOM   2461 N  N2    . DG  C 3 2   ? 9.12458   38.81659 24.13051 1.000 48.16759  ? 2   DG  C N2    1 
ATOM   2462 N  N3    . DG  C 3 2   ? 8.82520   39.28980 26.36224 1.000 50.73233  ? 2   DG  C N3    1 
ATOM   2463 C  C4    . DG  C 3 2   ? 9.43958   39.19675 27.56594 1.000 56.63344  ? 2   DG  C C4    1 
ATOM   2464 P  P     . DT  C 3 3   ? 4.03515   40.00788 30.30880 1.000 41.96902  ? 3   DT  C P     1 
ATOM   2465 O  OP1   . DT  C 3 3   ? 2.73984   40.60414 30.72258 1.000 42.20408  ? 3   DT  C OP1   1 
ATOM   2466 O  OP2   . DT  C 3 3   ? 4.57948   38.92276 31.14990 1.000 45.21395  ? 3   DT  C OP2   1 
ATOM   2467 O  "O5'" . DT  C 3 3   ? 3.91329   39.43632 28.82615 1.000 38.18441  ? 3   DT  C "O5'" 1 
ATOM   2468 C  "C5'" . DT  C 3 3   ? 3.67778   40.33088 27.74712 1.000 34.43695  ? 3   DT  C "C5'" 1 
ATOM   2469 C  "C4'" . DT  C 3 3   ? 3.58032   39.55323 26.44692 1.000 34.15785  ? 3   DT  C "C4'" 1 
ATOM   2470 O  "O4'" . DT  C 3 3   ? 4.89067   39.03557 26.08904 1.000 37.35892  ? 3   DT  C "O4'" 1 
ATOM   2471 C  "C3'" . DT  C 3 3   ? 2.64277   38.35658 26.48764 1.000 34.67087  ? 3   DT  C "C3'" 1 
ATOM   2472 O  "O3'" . DT  C 3 3   ? 1.90704   38.30156 25.26476 1.000 35.44448  ? 3   DT  C "O3'" 1 
ATOM   2473 C  "C2'" . DT  C 3 3   ? 3.58293   37.16186 26.65706 1.000 29.93346  ? 3   DT  C "C2'" 1 
ATOM   2474 C  "C1'" . DT  C 3 3   ? 4.84412   37.63382 25.94031 1.000 34.20658  ? 3   DT  C "C1'" 1 
ATOM   2475 N  N1    . DT  C 3 3   ? 6.12080   37.05469 26.50219 1.000 33.36952  ? 3   DT  C N1    1 
ATOM   2476 C  C2    . DT  C 3 3   ? 7.01588   36.44274 25.64720 1.000 35.55472  ? 3   DT  C C2    1 
ATOM   2477 O  O2    . DT  C 3 3   ? 6.82482   36.33546 24.45973 1.000 30.86153  ? 3   DT  C O2    1 
ATOM   2478 N  N3    . DT  C 3 3   ? 8.15122   35.95991 26.24660 1.000 32.85013  ? 3   DT  C N3    1 
ATOM   2479 C  C4    . DT  C 3 3   ? 8.47413   36.02446 27.58860 1.000 39.63525  ? 3   DT  C C4    1 
ATOM   2480 O  O4    . DT  C 3 3   ? 9.52127   35.55823 28.03165 1.000 38.87825  ? 3   DT  C O4    1 
ATOM   2481 C  C5    . DT  C 3 3   ? 7.49741   36.68212 28.43449 1.000 38.16513  ? 3   DT  C C5    1 
ATOM   2482 C  C7    . DT  C 3 3   ? 7.74693   36.81703 29.91313 1.000 42.97928  ? 3   DT  C C7    1 
ATOM   2483 C  C6    . DT  C 3 3   ? 6.38219   37.16248 27.85643 1.000 36.58565  ? 3   DT  C C6    1 
ATOM   2484 P  P     . DC  C 3 4   ? 0.73481   37.22515 25.04079 1.000 31.02271  ? 4   DC  C P     1 
ATOM   2485 O  OP1   . DC  C 3 4   ? -0.24194  37.89160 24.15302 1.000 31.88198  ? 4   DC  C OP1   1 
ATOM   2486 O  OP2   . DC  C 3 4   ? 0.26566   36.68089 26.34639 1.000 34.73347  ? 4   DC  C OP2   1 
ATOM   2487 O  "O5'" . DC  C 3 4   ? 1.45479   36.05187 24.26343 1.000 30.27631  ? 4   DC  C "O5'" 1 
ATOM   2488 C  "C5'" . DC  C 3 4   ? 2.04532   36.32038 23.01163 1.000 33.54898  ? 4   DC  C "C5'" 1 
ATOM   2489 C  "C4'" . DC  C 3 4   ? 2.82442   35.11567 22.53848 1.000 27.43200  ? 4   DC  C "C4'" 1 
ATOM   2490 O  "O4'" . DC  C 3 4   ? 3.96255   34.91486 23.39877 1.000 28.57330  ? 4   DC  C "O4'" 1 
ATOM   2491 C  "C3'" . DC  C 3 4   ? 2.05190   33.79490 22.53647 1.000 28.38673  ? 4   DC  C "C3'" 1 
ATOM   2492 O  "O3'" . DC  C 3 4   ? 2.05979   33.25152 21.20273 1.000 29.24303  ? 4   DC  C "O3'" 1 
ATOM   2493 C  "C2'" . DC  C 3 4   ? 2.81956   32.90210 23.52737 1.000 24.87927  ? 4   DC  C "C2'" 1 
ATOM   2494 C  "C1'" . DC  C 3 4   ? 4.19791   33.54726 23.51959 1.000 24.55709  ? 4   DC  C "C1'" 1 
ATOM   2495 N  N1    . DC  C 3 4   ? 4.99281   33.35102 24.75443 1.000 28.01993  ? 4   DC  C N1    1 
ATOM   2496 C  C2    . DC  C 3 4   ? 6.31495   32.90149 24.65240 1.000 29.77221  ? 4   DC  C C2    1 
ATOM   2497 O  O2    . DC  C 3 4   ? 6.77749   32.63867 23.53868 1.000 29.18705  ? 4   DC  C O2    1 
ATOM   2498 N  N3    . DC  C 3 4   ? 7.04971   32.75908 25.78371 1.000 30.81279  ? 4   DC  C N3    1 
ATOM   2499 C  C4    . DC  C 3 4   ? 6.51863   33.05774 26.97148 1.000 32.09083  ? 4   DC  C C4    1 
ATOM   2500 N  N4    . DC  C 3 4   ? 7.28777   32.89127 28.05788 1.000 30.72600  ? 4   DC  C N4    1 
ATOM   2501 C  C5    . DC  C 3 4   ? 5.17307   33.53355 27.10043 1.000 30.23937  ? 4   DC  C C5    1 
ATOM   2502 C  C6    . DC  C 3 4   ? 4.45572   33.67314 25.97313 1.000 28.82437  ? 4   DC  C C6    1 
ATOM   2503 P  P     . DC  C 3 5   ? 1.14254   31.99221 20.82759 1.000 28.56750  ? 5   DC  C P     1 
ATOM   2504 O  OP1   . DC  C 3 5   ? 1.00423   32.01424 19.34013 1.000 30.62659  ? 5   DC  C OP1   1 
ATOM   2505 O  OP2   . DC  C 3 5   ? -0.06416  31.99530 21.69408 1.000 30.44954  ? 5   DC  C OP2   1 
ATOM   2506 O  "O5'" . DC  C 3 5   ? 2.00594   30.75488 21.25391 1.000 27.05397  ? 5   DC  C "O5'" 1 
ATOM   2507 C  "C5'" . DC  C 3 5   ? 3.30197   30.55370 20.65381 1.000 26.39836  ? 5   DC  C "C5'" 1 
ATOM   2508 C  "C4'" . DC  C 3 5   ? 4.00586   29.39567 21.30579 1.000 26.00832  ? 5   DC  C "C4'" 1 
ATOM   2509 O  "O4'" . DC  C 3 5   ? 4.56834   29.82288 22.58000 1.000 25.51607  ? 5   DC  C "O4'" 1 
ATOM   2510 C  "C3'" . DC  C 3 5   ? 3.10784   28.18569 21.63470 1.000 27.69531  ? 5   DC  C "C3'" 1 
ATOM   2511 O  "O3'" . DC  C 3 5   ? 3.81794   26.99544 21.38400 1.000 27.43005  ? 5   DC  C "O3'" 1 
ATOM   2512 C  "C2'" . DC  C 3 5   ? 2.89808   28.34977 23.14127 1.000 24.60197  ? 5   DC  C "C2'" 1 
ATOM   2513 C  "C1'" . DC  C 3 5   ? 4.28861   28.81618 23.50893 1.000 25.95018  ? 5   DC  C "C1'" 1 
ATOM   2514 N  N1    . DC  C 3 5   ? 4.43676   29.34247 24.88290 1.000 25.36205  ? 5   DC  C N1    1 
ATOM   2515 C  C2    . DC  C 3 5   ? 5.67695   29.23494 25.49767 1.000 26.50726  ? 5   DC  C C2    1 
ATOM   2516 O  O2    . DC  C 3 5   ? 6.61037   28.73583 24.85944 1.000 27.70530  ? 5   DC  C O2    1 
ATOM   2517 N  N3    . DC  C 3 5   ? 5.83310   29.69908 26.74759 1.000 26.07411  ? 5   DC  C N3    1 
ATOM   2518 C  C4    . DC  C 3 5   ? 4.80025   30.23331 27.39768 1.000 29.34019  ? 5   DC  C C4    1 
ATOM   2519 N  N4    . DC  C 3 5   ? 5.00562   30.67612 28.63846 1.000 29.52191  ? 5   DC  C N4    1 
ATOM   2520 C  C5    . DC  C 3 5   ? 3.51284   30.35620 26.79186 1.000 27.54237  ? 5   DC  C C5    1 
ATOM   2521 C  C6    . DC  C 3 5   ? 3.37428   29.88951 25.53668 1.000 28.47755  ? 5   DC  C C6    1 
ATOM   2522 P  P     . DA  C 3 6   ? 3.57929   26.12253 20.06043 1.000 26.38352  ? 6   DA  C P     1 
ATOM   2523 O  OP1   . DA  C 3 6   ? 3.66494   27.00796 18.87616 1.000 25.34666  ? 6   DA  C OP1   1 
ATOM   2524 O  OP2   . DA  C 3 6   ? 2.30521   25.37569 20.19353 1.000 27.26817  ? 6   DA  C OP2   1 
ATOM   2525 O  "O5'" . DA  C 3 6   ? 4.79309   25.09273 20.14711 1.000 25.68324  ? 6   DA  C "O5'" 1 
ATOM   2526 C  "C5'" . DA  C 3 6   ? 6.12255   25.57364 19.83950 1.000 26.33252  ? 6   DA  C "C5'" 1 
ATOM   2527 C  "C4'" . DA  C 3 6   ? 7.17017   24.77942 20.59199 1.000 23.09214  ? 6   DA  C "C4'" 1 
ATOM   2528 O  "O4'" . DA  C 3 6   ? 7.16329   25.16760 21.98931 1.000 23.90275  ? 6   DA  C "O4'" 1 
ATOM   2529 C  "C3'" . DA  C 3 6   ? 6.95585   23.27575 20.58018 1.000 24.83771  ? 6   DA  C "C3'" 1 
ATOM   2530 O  "O3'" . DA  C 3 6   ? 8.21785   22.62659 20.60761 1.000 23.71595  ? 6   DA  C "O3'" 1 
ATOM   2531 C  "C2'" . DA  C 3 6   ? 6.16263   23.02780 21.86683 1.000 26.35988  ? 6   DA  C "C2'" 1 
ATOM   2532 C  "C1'" . DA  C 3 6   ? 6.76726   24.06393 22.81319 1.000 23.96980  ? 6   DA  C "C1'" 1 
ATOM   2533 N  N9    . DA  C 3 6   ? 5.83529   24.60910 23.79420 1.000 24.81737  ? 6   DA  C N9    1 
ATOM   2534 C  C8    . DA  C 3 6   ? 4.48899   24.82196 23.63151 1.000 26.60650  ? 6   DA  C C8    1 
ATOM   2535 N  N7    . DA  C 3 6   ? 3.92650   25.40328 24.66106 1.000 25.56329  ? 6   DA  C N7    1 
ATOM   2536 C  C5    . DA  C 3 6   ? 4.97206   25.60433 25.54478 1.000 24.44096  ? 6   DA  C C5    1 
ATOM   2537 C  C6    . DA  C 3 6   ? 5.02822   26.19426 26.81619 1.000 26.02272  ? 6   DA  C C6    1 
ATOM   2538 N  N6    . DA  C 3 6   ? 3.96339   26.70696 27.42852 1.000 25.21359  ? 6   DA  C N6    1 
ATOM   2539 N  N1    . DA  C 3 6   ? 6.22132   26.24008 27.43703 1.000 25.82467  ? 6   DA  C N1    1 
ATOM   2540 C  C2    . DA  C 3 6   ? 7.29651   25.74614 26.80278 1.000 24.55968  ? 6   DA  C C2    1 
ATOM   2541 N  N3    . DA  C 3 6   ? 7.36821   25.17989 25.58632 1.000 23.67101  ? 6   DA  C N3    1 
ATOM   2542 C  C4    . DA  C 3 6   ? 6.15809   25.14574 25.00929 1.000 22.88775  ? 6   DA  C C4    1 
HETATM 2543 O  "O5'" . 3DR C 3 7   ? 8.77740   20.40504 19.54256 1.000 29.62142  ? 7   3DR C "O5'" 1 
HETATM 2544 P  P     . 3DR C 3 7   ? 8.86130   21.97791 19.30066 1.000 24.45411  ? 7   3DR C P     1 
HETATM 2545 O  OP1   . 3DR C 3 7   ? 10.30725  22.38017 19.22254 1.000 28.18190  ? 7   3DR C OP1   1 
HETATM 2546 O  OP2   . 3DR C 3 7   ? 8.06189   22.32562 18.05838 1.000 32.09924  ? 7   3DR C OP2   1 
HETATM 2547 C  "C2'" . 3DR C 3 7   ? 5.84779   16.83632 19.77583 1.000 24.45005  ? 7   3DR C "C2'" 1 
HETATM 2548 C  "C5'" . 3DR C 3 7   ? 7.70286   19.87365 20.31159 1.000 25.94967  ? 7   3DR C "C5'" 1 
HETATM 2549 C  "C4'" . 3DR C 3 7   ? 6.74336   19.08472 19.42269 1.000 24.85460  ? 7   3DR C "C4'" 1 
HETATM 2550 O  "O4'" . 3DR C 3 7   ? 7.48811   18.14421 18.65975 1.000 32.87576  ? 7   3DR C "O4'" 1 
HETATM 2551 C  "C1'" . 3DR C 3 7   ? 6.86704   16.85115 18.66298 1.000 28.22267  ? 7   3DR C "C1'" 1 
HETATM 2552 C  "C3'" . 3DR C 3 7   ? 5.74335   18.27506 20.21780 1.000 22.98588  ? 7   3DR C "C3'" 1 
HETATM 2553 O  "O3'" . 3DR C 3 7   ? 4.41880   18.71608 19.89356 1.000 22.95426  ? 7   3DR C "O3'" 1 
ATOM   2554 P  P     . DG  C 3 8   ? 3.43488   19.21151 21.04387 1.000 23.27724  ? 8   DG  C P     1 
ATOM   2555 O  OP1   . DG  C 3 8   ? 2.19974   19.58665 20.30171 1.000 23.82171  ? 8   DG  C OP1   1 
ATOM   2556 O  OP2   . DG  C 3 8   ? 4.09627   20.21450 21.91030 1.000 22.87627  ? 8   DG  C OP2   1 
ATOM   2557 O  "O5'" . DG  C 3 8   ? 3.16318   17.91599 21.91041 1.000 24.91190  ? 8   DG  C "O5'" 1 
ATOM   2558 C  "C5'" . DG  C 3 8   ? 2.12983   17.01615 21.57557 1.000 25.24442  ? 8   DG  C "C5'" 1 
ATOM   2559 C  "C4'" . DG  C 3 8   ? 2.01459   15.98542 22.67347 1.000 25.16138  ? 8   DG  C "C4'" 1 
ATOM   2560 O  "O4'" . DG  C 3 8   ? 1.86269   16.66677 23.94874 1.000 26.51137  ? 8   DG  C "O4'" 1 
ATOM   2561 C  "C3'" . DG  C 3 8   ? 0.84124   15.02969 22.56759 1.000 23.19753  ? 8   DG  C "C3'" 1 
ATOM   2562 O  "O3'" . DG  C 3 8   ? 1.24051   13.76638 23.15129 1.000 24.20256  ? 8   DG  C "O3'" 1 
ATOM   2563 C  "C2'" . DG  C 3 8   ? -0.23667  15.73313 23.39890 1.000 23.44820  ? 8   DG  C "C2'" 1 
ATOM   2564 C  "C1'" . DG  C 3 8   ? 0.58046   16.42612 24.48618 1.000 25.60607  ? 8   DG  C "C1'" 1 
ATOM   2565 N  N9    . DG  C 3 8   ? 0.00950   17.70055 24.91417 1.000 26.05625  ? 8   DG  C N9    1 
ATOM   2566 C  C8    . DG  C 3 8   ? -0.42809  18.72888 24.11204 1.000 27.09324  ? 8   DG  C C8    1 
ATOM   2567 N  N7    . DG  C 3 8   ? -0.89409  19.74697 24.78570 1.000 27.76654  ? 8   DG  C N7    1 
ATOM   2568 C  C5    . DG  C 3 8   ? -0.76116  19.36787 26.11751 1.000 27.69974  ? 8   DG  C C5    1 
ATOM   2569 C  C6    . DG  C 3 8   ? -1.10379  20.07167 27.29572 1.000 25.17697  ? 8   DG  C C6    1 
ATOM   2570 O  O6    . DG  C 3 8   ? -1.61378  21.19927 27.39104 1.000 26.40996  ? 8   DG  C O6    1 
ATOM   2571 N  N1    . DG  C 3 8   ? -0.80572  19.32105 28.45586 1.000 24.22456  ? 8   DG  C N1    1 
ATOM   2572 C  C2    . DG  C 3 8   ? -0.23586  18.06410 28.44243 1.000 24.40267  ? 8   DG  C C2    1 
ATOM   2573 N  N2    . DG  C 3 8   ? -0.00883  17.49194 29.64350 1.000 24.45019  ? 8   DG  C N2    1 
ATOM   2574 N  N3    . DG  C 3 8   ? 0.08243   17.40071 27.32053 1.000 23.50769  ? 8   DG  C N3    1 
ATOM   2575 C  C4    . DG  C 3 8   ? -0.21285  18.11079 26.21239 1.000 25.16167  ? 8   DG  C C4    1 
ATOM   2576 P  P     . DT  C 3 9   ? 0.23426   12.52473 23.21483 1.000 23.40399  ? 9   DT  C P     1 
ATOM   2577 O  OP1   . DT  C 3 9   ? 1.05284   11.32347 22.99845 1.000 23.38008  ? 9   DT  C OP1   1 
ATOM   2578 O  OP2   . DT  C 3 9   ? -0.96703  12.71851 22.38305 1.000 24.48504  ? 9   DT  C OP2   1 
ATOM   2579 O  "O5'" . DT  C 3 9   ? -0.23149  12.55167 24.74621 1.000 23.33967  ? 9   DT  C "O5'" 1 
ATOM   2580 C  "C5'" . DT  C 3 9   ? 0.77041   12.32639 25.73796 1.000 22.70244  ? 9   DT  C "C5'" 1 
ATOM   2581 C  "C4'" . DT  C 3 9   ? 0.13470   12.25754 27.10568 1.000 24.24820  ? 9   DT  C "C4'" 1 
ATOM   2582 O  "O4'" . DT  C 3 9   ? -0.36529  13.56437 27.45453 1.000 24.07755  ? 9   DT  C "O4'" 1 
ATOM   2583 C  "C3'" . DT  C 3 9   ? -1.03479  11.28445 27.23401 1.000 26.55465  ? 9   DT  C "C3'" 1 
ATOM   2584 O  "O3'" . DT  C 3 9   ? -0.79342  10.42702 28.35895 1.000 29.27079  ? 9   DT  C "O3'" 1 
ATOM   2585 C  "C2'" . DT  C 3 9   ? -2.27373  12.19711 27.41853 1.000 27.21657  ? 9   DT  C "C2'" 1 
ATOM   2586 C  "C1'" . DT  C 3 9   ? -1.66079  13.44404 28.03425 1.000 26.25678  ? 9   DT  C "C1'" 1 
ATOM   2587 N  N1    . DT  C 3 9   ? -2.36735  14.73194 27.74879 1.000 25.72824  ? 9   DT  C N1    1 
ATOM   2588 C  C2    . DT  C 3 9   ? -2.71151  15.55999 28.80939 1.000 25.98308  ? 9   DT  C C2    1 
ATOM   2589 O  O2    . DT  C 3 9   ? -2.53701  15.25685 29.97364 1.000 27.60846  ? 9   DT  C O2    1 
ATOM   2590 N  N3    . DT  C 3 9   ? -3.27729  16.74667 28.44954 1.000 26.74345  ? 9   DT  C N3    1 
ATOM   2591 C  C4    . DT  C 3 9   ? -3.52602  17.18902 27.15246 1.000 27.30508  ? 9   DT  C C4    1 
ATOM   2592 O  O4    . DT  C 3 9   ? -4.02995  18.27462 26.90884 1.000 27.72456  ? 9   DT  C O4    1 
ATOM   2593 C  C5    . DT  C 3 9   ? -3.13134  16.29332 26.09873 1.000 26.79139  ? 9   DT  C C5    1 
ATOM   2594 C  C7    . DT  C 3 9   ? -3.37651  16.68851 24.66319 1.000 24.99966  ? 9   DT  C C7    1 
ATOM   2595 C  C6    . DT  C 3 9   ? -2.56596  15.12999 26.43471 1.000 26.05250  ? 9   DT  C C6    1 
ATOM   2596 P  P     . DC  C 3 10  ? -1.73868  9.16038  28.65885 1.000 29.37258  ? 10  DC  C P     1 
ATOM   2597 O  OP1   . DC  C 3 10  ? -0.96357  8.24998  29.52728 1.000 31.57309  ? 10  DC  C OP1   1 
ATOM   2598 O  OP2   . DC  C 3 10  ? -2.41434  8.70974  27.42909 1.000 35.58918  ? 10  DC  C OP2   1 
ATOM   2599 O  "O5'" . DC  C 3 10  ? -2.88538  9.77256  29.59507 1.000 29.85650  ? 10  DC  C "O5'" 1 
ATOM   2600 C  "C5'" . DC  C 3 10  ? -2.55358  10.33972 30.84367 1.000 32.33683  ? 10  DC  C "C5'" 1 
ATOM   2601 C  "C4'" . DC  C 3 10  ? -3.77030  11.00267 31.45171 1.000 37.92034  ? 10  DC  C "C4'" 1 
ATOM   2602 O  "O4'" . DC  C 3 10  ? -4.08774  12.20416 30.71825 1.000 40.69044  ? 10  DC  C "O4'" 1 
ATOM   2603 C  "C3'" . DC  C 3 10  ? -5.04409  10.15027 31.43490 1.000 38.31174  ? 10  DC  C "C3'" 1 
ATOM   2604 O  "O3'" . DC  C 3 10  ? -5.47687  9.95755  32.76802 1.000 61.31621  ? 10  DC  C "O3'" 1 
ATOM   2605 C  "C2'" . DC  C 3 10  ? -6.05697  10.98451 30.61630 1.000 44.05229  ? 10  DC  C "C2'" 1 
ATOM   2606 C  "C1'" . DC  C 3 10  ? -5.48015  12.38570 30.73210 1.000 40.72742  ? 10  DC  C "C1'" 1 
ATOM   2607 N  N1    . DC  C 3 10  ? -5.82025  13.31449 29.60914 1.000 39.30687  ? 10  DC  C N1    1 
ATOM   2608 C  C2    . DC  C 3 10  ? -6.19992  14.62719 29.90179 1.000 36.47217  ? 10  DC  C C2    1 
ATOM   2609 O  O2    . DC  C 3 10  ? -6.26614  14.97831 31.08312 1.000 39.61465  ? 10  DC  C O2    1 
ATOM   2610 N  N3    . DC  C 3 10  ? -6.47730  15.47869 28.87802 1.000 34.07494  ? 10  DC  C N3    1 
ATOM   2611 C  C4    . DC  C 3 10  ? -6.36216  15.06747 27.62201 1.000 31.70774  ? 10  DC  C C4    1 
ATOM   2612 N  N4    . DC  C 3 10  ? -6.64211  15.94413 26.64755 1.000 34.53304  ? 10  DC  C N4    1 
ATOM   2613 C  C5    . DC  C 3 10  ? -5.96914  13.73147 27.30086 1.000 34.29838  ? 10  DC  C C5    1 
ATOM   2614 C  C6    . DC  C 3 10  ? -5.70727  12.89973 28.31887 1.000 30.67959  ? 10  DC  C C6    1 
ATOM   2615 P  P     . DT  C 3 11  ? -6.35723  8.67747  33.18175 1.000 61.27528  ? 11  DT  C P     1 
ATOM   2616 O  OP1   . DT  C 3 11  ? -5.63279  8.04625  34.31476 1.000 51.39556  ? 11  DT  C OP1   1 
ATOM   2617 O  OP2   . DT  C 3 11  ? -6.70286  7.91117  31.95535 1.000 52.74481  ? 11  DT  C OP2   1 
ATOM   2618 O  "O5'" . DT  C 3 11  ? -7.71917  9.33163  33.71571 1.000 56.52792  ? 11  DT  C "O5'" 1 
ATOM   2619 C  "C5'" . DT  C 3 11  ? -7.67039  10.42379 34.63549 1.000 52.72956  ? 11  DT  C "C5'" 1 
ATOM   2620 C  "C4'" . DT  C 3 11  ? -8.88791  11.32054 34.47406 1.000 55.66032  ? 11  DT  C "C4'" 1 
ATOM   2621 O  "O4'" . DT  C 3 11  ? -8.72720  12.16131 33.30822 1.000 51.38138  ? 11  DT  C "O4'" 1 
ATOM   2622 C  "C3'" . DT  C 3 11  ? -10.22116 10.58391 34.28050 1.000 56.17903  ? 11  DT  C "C3'" 1 
ATOM   2623 O  "O3'" . DT  C 3 11  ? -11.12429 10.93508 35.32347 1.000 57.69026  ? 11  DT  C "O3'" 1 
ATOM   2624 C  "C2'" . DT  C 3 11  ? -10.72533 11.06846 32.91070 1.000 53.29350  ? 11  DT  C "C2'" 1 
ATOM   2625 C  "C1'" . DT  C 3 11  ? -9.98942  12.38947 32.75450 1.000 50.45976  ? 11  DT  C "C1'" 1 
ATOM   2626 N  N1    . DT  C 3 11  ? -9.82186  12.81873 31.33949 1.000 39.39286  ? 11  DT  C N1    1 
ATOM   2627 C  C2    . DT  C 3 11  ? -9.95222  14.15237 31.01737 1.000 42.88363  ? 11  DT  C C2    1 
ATOM   2628 O  O2    . DT  C 3 11  ? -10.18844 15.02007 31.83814 1.000 47.39410  ? 11  DT  C O2    1 
ATOM   2629 N  N3    . DT  C 3 11  ? -9.78814  14.43872 29.68924 1.000 44.28232  ? 11  DT  C N3    1 
ATOM   2630 C  C4    . DT  C 3 11  ? -9.51908  13.54506 28.67402 1.000 44.42544  ? 11  DT  C C4    1 
ATOM   2631 O  O4    . DT  C 3 11  ? -9.38728  13.89778 27.50581 1.000 42.22689  ? 11  DT  C O4    1 
ATOM   2632 C  C5    . DT  C 3 11  ? -9.40373  12.16420 29.07950 1.000 40.21637  ? 11  DT  C C5    1 
ATOM   2633 C  C7    . DT  C 3 11  ? -9.10902  11.10487 28.05764 1.000 47.68430  ? 11  DT  C C7    1 
ATOM   2634 C  C6    . DT  C 3 11  ? -9.55403  11.87281 30.37661 1.000 41.01415  ? 11  DT  C C6    1 
HETATM 2635 NA NA    . NA  D 4 .   ? 5.46900   34.05682 14.11542 1.000 37.06279  ? 301 NA  A NA    1 
HETATM 2636 NA NA    . NA  E 4 .   ? 18.91231  4.25817  39.51057 1.000 42.98546  ? 302 NA  A NA    1 
HETATM 2637 MG MG    . MG  F 5 .   ? -1.82908  5.99148  27.19749 1.000 32.68148  ? 303 MG  A MG    1 
HETATM 2638 CL CL    . CL  G 6 .   ? -2.95266  28.04578 40.08080 1.000 59.82567  ? 304 CL  A CL    1 
HETATM 2639 P  P     . PO4 H 7 .   ? -1.99562  32.25248 9.37983  1.000 42.45803  ? 305 PO4 A P     1 
HETATM 2640 O  O1    . PO4 H 7 .   ? -2.47720  33.12214 8.23052  1.000 49.38421  ? 305 PO4 A O1    1 
HETATM 2641 O  O2    . PO4 H 7 .   ? -0.60410  32.69209 9.78610  1.000 37.05545  ? 305 PO4 A O2    1 
HETATM 2642 O  O3    . PO4 H 7 .   ? -1.94944  30.81901 8.89650  1.000 35.15501  ? 305 PO4 A O3    1 
HETATM 2643 O  O4    . PO4 H 7 .   ? -2.94248  32.39664 10.55033 1.000 38.31762  ? 305 PO4 A O4    1 
HETATM 2644 C  C1    . EDO I 8 .   ? 6.13695   18.22465 39.93837 1.000 25.55806  ? 306 EDO A C1    1 
HETATM 2645 O  O1    . EDO I 8 .   ? 5.95522   19.42760 39.17657 1.000 28.78814  ? 306 EDO A O1    1 
HETATM 2646 C  C2    . EDO I 8 .   ? 4.89504   17.36355 39.81887 1.000 25.77965  ? 306 EDO A C2    1 
HETATM 2647 O  O2    . EDO I 8 .   ? 4.53190   17.07702 38.46280 1.000 24.60849  ? 306 EDO A O2    1 
HETATM 2648 H  H11   . EDO I 8 .   ? 6.31841   18.47207 40.98638 1.000 30.64601  ? 306 EDO A H11   1 
HETATM 2649 H  H12   . EDO I 8 .   ? 7.00601   17.67732 39.56738 1.000 30.64601  ? 306 EDO A H12   1 
HETATM 2650 H  HO1   . EDO I 8 .   ? 6.77595   19.93895 39.18094 1.000 34.52211  ? 306 EDO A HO1   1 
HETATM 2651 H  H21   . EDO I 8 .   ? 4.06257   17.87462 40.30699 1.000 30.91192  ? 306 EDO A H21   1 
HETATM 2652 H  H22   . EDO I 8 .   ? 5.06598   16.42215 40.34519 1.000 30.91192  ? 306 EDO A H22   1 
HETATM 2653 H  HO2   . EDO I 8 .   ? 3.76901   16.48291 38.45207 1.000 29.50653  ? 306 EDO A HO2   1 
HETATM 2654 C  C1    . EDO J 8 .   ? -1.65019  25.75892 22.86234 1.000 40.82889  ? 307 EDO A C1    1 
HETATM 2655 O  O1    . EDO J 8 .   ? -3.05905  25.82193 23.12909 1.000 44.36710  ? 307 EDO A O1    1 
HETATM 2656 C  C2    . EDO J 8 .   ? -1.27590  27.00785 22.08914 1.000 41.76975  ? 307 EDO A C2    1 
HETATM 2657 O  O2    . EDO J 8 .   ? -1.90858  26.92554 20.80705 1.000 41.94357  ? 307 EDO A O2    1 
HETATM 2658 H  H11   . EDO J 8 .   ? -1.41339  24.86618 22.27976 1.000 48.97100  ? 307 EDO A H11   1 
HETATM 2659 H  H12   . EDO J 8 .   ? -1.08838  25.70831 23.79737 1.000 48.97100  ? 307 EDO A H12   1 
HETATM 2660 H  HO1   . EDO J 8 .   ? -3.31301  25.08155 23.69692 1.000 53.21686  ? 307 EDO A HO1   1 
HETATM 2661 H  H21   . EDO J 8 .   ? -0.19191  27.07344 21.97460 1.000 50.10004  ? 307 EDO A H21   1 
HETATM 2662 H  H22   . EDO J 8 .   ? -1.61167  27.89982 22.62216 1.000 50.10004  ? 307 EDO A H22   1 
HETATM 2663 H  HO2   . EDO J 8 .   ? -2.86887  26.93129 20.92054 1.000 50.30862  ? 307 EDO A HO2   1 
HETATM 2664 C  C1    . EDO K 8 .   ? 13.17672  4.92846  44.94222 1.000 47.13032  ? 308 EDO A C1    1 
HETATM 2665 O  O1    . EDO K 8 .   ? 13.43906  6.15243  44.23981 1.000 35.88204  ? 308 EDO A O1    1 
HETATM 2666 C  C2    . EDO K 8 .   ? 12.02500  4.17556  44.28724 1.000 45.20235  ? 308 EDO A C2    1 
HETATM 2667 O  O2    . EDO K 8 .   ? 12.46089  3.57678  43.05954 1.000 42.03311  ? 308 EDO A O2    1 
HETATM 2668 H  H11   . EDO K 8 .   ? 12.92636  5.14891  45.98202 1.000 56.53272  ? 308 EDO A H11   1 
HETATM 2669 H  H12   . EDO K 8 .   ? 14.07253  4.30400  44.93782 1.000 56.53272  ? 308 EDO A H12   1 
HETATM 2670 H  HO1   . EDO K 8 .   ? 14.17945  6.61217  44.65880 1.000 43.03478  ? 308 EDO A HO1   1 
HETATM 2671 H  H21   . EDO K 8 .   ? 11.20111  4.86416  44.08851 1.000 54.21916  ? 308 EDO A H21   1 
HETATM 2672 H  H22   . EDO K 8 .   ? 11.65921  3.40116  44.96470 1.000 54.21916  ? 308 EDO A H22   1 
HETATM 2673 H  HO2   . EDO K 8 .   ? 11.72097  3.10918  42.64847 1.000 50.41607  ? 308 EDO A HO2   1 
HETATM 2674 C  C1    . EDO L 8 .   ? 1.54288   11.69829 31.28982 1.000 38.39567  ? 309 EDO A C1    1 
HETATM 2675 O  O1    . EDO L 8 .   ? 2.47011   12.79184 31.26565 1.000 37.15130  ? 309 EDO A O1    1 
HETATM 2676 C  C2    . EDO L 8 .   ? 1.04696   11.46687 32.71378 1.000 39.20290  ? 309 EDO A C2    1 
HETATM 2677 O  O2    . EDO L 8 .   ? -0.14388  12.23023 32.94272 1.000 45.56207  ? 309 EDO A O2    1 
HETATM 2678 H  H11   . EDO L 8 .   ? 2.02912   10.79429 30.91724 1.000 46.05114  ? 309 EDO A H11   1 
HETATM 2679 H  H12   . EDO L 8 .   ? 0.69648   11.91803 30.63576 1.000 46.05114  ? 309 EDO A H12   1 
HETATM 2680 H  HO1   . EDO L 8 .   ? 2.80547   12.91025 30.36643 1.000 44.55789  ? 309 EDO A HO1   1 
HETATM 2681 H  H21   . EDO L 8 .   ? 1.81897   11.76360 33.42682 1.000 47.01982  ? 309 EDO A H21   1 
HETATM 2682 H  H22   . EDO L 8 .   ? 0.84033   10.40534 32.86525 1.000 47.01982  ? 309 EDO A H22   1 
HETATM 2683 H  HO2   . EDO L 8 .   ? -0.43862  12.10193 33.85473 1.000 54.65081  ? 309 EDO A HO2   1 
HETATM 2684 C  C1    . EDO M 8 .   ? 20.52841  19.31481 30.90668 1.000 40.99265  ? 310 EDO A C1    1 
HETATM 2685 O  O1    . EDO M 8 .   ? 21.69974  19.76368 30.20933 1.000 47.84788  ? 310 EDO A O1    1 
HETATM 2686 C  C2    . EDO M 8 .   ? 20.37668  20.08298 32.21242 1.000 43.30862  ? 310 EDO A C2    1 
HETATM 2687 O  O2    . EDO M 8 .   ? 21.51231  19.82374 33.04644 1.000 52.52149  ? 310 EDO A O2    1 
HETATM 2688 H  H11   . EDO M 8 .   ? 20.60958  18.24587 31.11461 1.000 49.16752  ? 310 EDO A H11   1 
HETATM 2689 H  H12   . EDO M 8 .   ? 19.64556  19.46930 30.28284 1.000 49.16752  ? 310 EDO A H12   1 
HETATM 2690 H  HO1   . EDO M 8 .   ? 21.76157  19.30982 29.35770 1.000 57.39379  ? 310 EDO A HO1   1 
HETATM 2691 H  H21   . EDO M 8 .   ? 19.46198  19.77341 32.72228 1.000 51.94668  ? 310 EDO A H21   1 
HETATM 2692 H  H22   . EDO M 8 .   ? 20.30136  21.15306 32.00818 1.000 51.94668  ? 310 EDO A H22   1 
HETATM 2693 H  HO2   . EDO M 8 .   ? 21.41010  20.29370 33.88535 1.000 63.00213  ? 310 EDO A HO2   1 
HETATM 2694 C  C1    . EDO N 8 .   ? -3.74502  23.77145 19.96375 1.000 40.56023  ? 311 EDO A C1    1 
HETATM 2695 O  O1    . EDO N 8 .   ? -2.67487  24.67769 19.63660 1.000 38.95756  ? 311 EDO A O1    1 
HETATM 2696 C  C2    . EDO N 8 .   ? -3.38576  23.04367 21.25938 1.000 46.09764  ? 311 EDO A C2    1 
HETATM 2697 O  O2    . EDO N 8 .   ? -4.37975  22.07202 21.60988 1.000 51.87366  ? 311 EDO A O2    1 
HETATM 2698 H  H11   . EDO N 8 .   ? -3.88717  23.05103 19.15551 1.000 48.64861  ? 311 EDO A H11   1 
HETATM 2699 H  H12   . EDO N 8 .   ? -4.67892  24.32321 20.08966 1.000 48.64861  ? 311 EDO A H12   1 
HETATM 2700 H  HO1   . EDO N 8 .   ? -2.88451  25.14035 18.81375 1.000 46.72540  ? 311 EDO A HO1   1 
HETATM 2701 H  H21   . EDO N 8 .   ? -3.29026  23.77114 22.06817 1.000 55.29350  ? 311 EDO A H21   1 
HETATM 2702 H  H22   . EDO N 8 .   ? -2.42085  22.54669 21.13930 1.000 55.29350  ? 311 EDO A H22   1 
HETATM 2703 H  HO2   . EDO N 8 .   ? -4.15626  21.67565 22.46313 1.000 62.22473  ? 311 EDO A HO2   1 
HETATM 2704 C  C1    . EDO O 8 .   ? 6.92500   3.45839  38.70763 1.000 47.90178  ? 312 EDO A C1    1 
HETATM 2705 O  O1    . EDO O 8 .   ? 7.06977   3.42003  40.13271 1.000 65.03377  ? 312 EDO A O1    1 
HETATM 2706 C  C2    . EDO O 8 .   ? 6.34874   4.79973  38.26373 1.000 46.09779  ? 312 EDO A C2    1 
HETATM 2707 O  O2    . EDO O 8 .   ? 7.24602   5.86019  38.60499 1.000 53.01677  ? 312 EDO A O2    1 
HETATM 2708 H  H11   . EDO O 8 .   ? 6.26407   2.65122  38.38496 1.000 57.45847  ? 312 EDO A H11   1 
HETATM 2709 H  H12   . EDO O 8 .   ? 7.89800   3.30406  38.23654 1.000 57.45847  ? 312 EDO A H12   1 
HETATM 2710 H  HO1   . EDO O 8 .   ? 7.44798   2.56974  40.39549 1.000 78.01685  ? 312 EDO A HO1   1 
HETATM 2711 H  H21   . EDO O 8 .   ? 5.38413   4.96398  38.74851 1.000 55.29368  ? 312 EDO A H21   1 
HETATM 2712 H  H22   . EDO O 8 .   ? 6.18453   4.79015  37.18419 1.000 55.29368  ? 312 EDO A H22   1 
HETATM 2713 H  HO2   . EDO O 8 .   ? 6.87671   6.70305  38.30786 1.000 63.59646  ? 312 EDO A HO2   1 
HETATM 2714 C  C1    . EDO P 8 .   ? -0.03379  31.81122 45.89799 1.000 49.73616  ? 313 EDO A C1    1 
HETATM 2715 O  O1    . EDO P 8 .   ? 1.34901   32.05519 46.19198 1.000 50.81255  ? 313 EDO A O1    1 
HETATM 2716 C  C2    . EDO P 8 .   ? -0.55545  32.85022 44.91123 1.000 49.39882  ? 313 EDO A C2    1 
HETATM 2717 O  O2    . EDO P 8 .   ? -1.42003  32.21923 43.95180 1.000 60.41672  ? 313 EDO A O2    1 
HETATM 2718 H  H11   . EDO P 8 .   ? -0.61830  31.85370 46.81941 1.000 59.65972  ? 313 EDO A H11   1 
HETATM 2719 H  H12   . EDO P 8 .   ? -0.14832  30.81157 45.47367 1.000 59.65972  ? 313 EDO A H12   1 
HETATM 2720 H  HO1   . EDO P 8 .   ? 1.69169   31.34056 46.74603 1.000 60.95139  ? 313 EDO A HO1   1 
HETATM 2721 H  H21   . EDO P 8 .   ? 0.28274   33.32523 44.39716 1.000 59.25491  ? 313 EDO A H21   1 
HETATM 2722 H  H22   . EDO P 8 .   ? -1.10377  33.62715 45.44805 1.000 59.25491  ? 313 EDO A H22   1 
HETATM 2723 H  HO2   . EDO P 8 .   ? -1.72809  32.87730 43.31373 1.000 72.47640  ? 313 EDO A HO2   1 
HETATM 2724 C  C1    . EDO Q 8 .   ? 21.81700  7.27675  22.14487 1.000 50.09320  ? 314 EDO A C1    1 
HETATM 2725 O  O1    . EDO Q 8 .   ? 23.10020  7.35232  21.51389 1.000 61.40444  ? 314 EDO A O1    1 
HETATM 2726 C  C2    . EDO Q 8 .   ? 20.94477  6.30103  21.36375 1.000 50.54753  ? 314 EDO A C2    1 
HETATM 2727 O  O2    . EDO Q 8 .   ? 21.02560  6.60269  19.96489 1.000 54.67270  ? 314 EDO A O2    1 
HETATM 2728 H  H11   . EDO Q 8 .   ? 21.35027  8.26380  22.16380 1.000 60.08817  ? 314 EDO A H11   1 
HETATM 2729 H  H12   . EDO Q 8 .   ? 21.92661  6.93747  23.17702 1.000 60.08817  ? 314 EDO A H12   1 
HETATM 2730 H  HO1   . EDO Q 8 .   ? 23.68072  7.92665  22.03179 1.000 73.66166  ? 314 EDO A HO1   1 
HETATM 2731 H  H21   . EDO Q 8 .   ? 19.90887  6.37772  21.70064 1.000 60.63338  ? 314 EDO A H21   1 
HETATM 2732 H  H22   . EDO Q 8 .   ? 21.28100  5.27760  21.54268 1.000 60.63338  ? 314 EDO A H22   1 
HETATM 2733 H  HO2   . EDO Q 8 .   ? 20.42938  6.02026  19.47460 1.000 65.58358  ? 314 EDO A HO2   1 
HETATM 2734 C  C1    . EDO R 8 .   ? -3.59042  25.84642 33.61929 1.000 49.61100  ? 315 EDO A C1    1 
HETATM 2735 O  O1    . EDO R 8 .   ? -2.31710  26.48925 33.54200 1.000 52.52139  ? 315 EDO A O1    1 
HETATM 2736 C  C2    . EDO R 8 .   ? -3.58450  24.96615 34.86167 1.000 45.03040  ? 315 EDO A C2    1 
HETATM 2737 O  O2    . EDO R 8 .   ? -3.56594  25.80741 36.02900 1.000 54.31993  ? 315 EDO A O2    1 
HETATM 2738 H  H11   . EDO R 8 .   ? -3.76598  25.24252 32.72658 1.000 59.50953  ? 315 EDO A H11   1 
HETATM 2739 H  H12   . EDO R 8 .   ? -4.38792  26.58957 33.68397 1.000 59.50953  ? 315 EDO A H12   1 
HETATM 2740 H  HO1   . EDO R 8 .   ? -2.40930  27.41837 33.79365 1.000 63.00200  ? 315 EDO A HO1   1 
HETATM 2741 H  H21   . EDO R 8 .   ? -2.70666  24.31667 34.85521 1.000 54.01281  ? 315 EDO A H21   1 
HETATM 2742 H  H22   . EDO R 8 .   ? -4.47228  24.33042 34.87337 1.000 54.01281  ? 315 EDO A H22   1 
HETATM 2743 H  HO2   . EDO R 8 .   ? -3.66199  25.26143 36.82132 1.000 65.16025  ? 315 EDO A HO2   1 
HETATM 2744 C  C1    . EDO S 8 .   ? -1.01293  13.21705 59.71588 1.000 49.87805  ? 316 EDO A C1    1 
HETATM 2745 O  O1    . EDO S 8 .   ? -0.78127  12.93057 58.32854 1.000 65.84838  ? 316 EDO A O1    1 
HETATM 2746 C  C2    . EDO S 8 .   ? 0.28241   13.06739 60.50797 1.000 46.22280  ? 316 EDO A C2    1 
HETATM 2747 O  O2    . EDO S 8 .   ? 0.36435   11.74562 61.05969 1.000 54.31704  ? 316 EDO A O2    1 
HETATM 2748 H  H11   . EDO S 8 .   ? -1.76698  12.53347 60.11158 1.000 59.83000  ? 316 EDO A H11   1 
HETATM 2749 H  H12   . EDO S 8 .   ? -1.39366  14.23496 59.82257 1.000 59.83000  ? 316 EDO A H12   1 
HETATM 2750 H  HO1   . EDO S 8 .   ? -1.54195  13.22254 57.80775 1.000 78.99439  ? 316 EDO A HO1   1 
HETATM 2751 H  H21   . EDO S 8 .   ? 0.31145   13.80588 61.31187 1.000 55.44369  ? 316 EDO A H21   1 
HETATM 2752 H  H22   . EDO S 8 .   ? 1.13827   13.24881 59.85448 1.000 55.44369  ? 316 EDO A H22   1 
HETATM 2753 H  HO2   . EDO S 8 .   ? 1.20647   11.64157 61.52348 1.000 65.15678  ? 316 EDO A HO2   1 
HETATM 2754 MG MG    . MG  T 5 .   ? 4.65842   32.14190 31.94091 1.000 59.61710  ? 101 MG  B MG    1 
HETATM 2755 C  C1    . EDO U 8 .   ? -3.25319  37.29133 25.60415 1.000 35.41185  ? 101 EDO C C1    1 
HETATM 2756 O  O1    . EDO U 8 .   ? -2.84147  38.45445 24.87221 1.000 36.25226  ? 101 EDO C O1    1 
HETATM 2757 C  C2    . EDO U 8 .   ? -3.25402  37.62649 27.08778 1.000 40.05865  ? 101 EDO C C2    1 
HETATM 2758 O  O2    . EDO U 8 .   ? -4.35991  38.49235 27.36910 1.000 33.92687  ? 101 EDO C O2    1 
HETATM 2759 H  H11   . EDO U 8 .   ? -2.56946  36.46295 25.40728 1.000 42.47056  ? 101 EDO C H11   1 
HETATM 2760 H  H12   . EDO U 8 .   ? -4.25242  36.98401 25.28863 1.000 42.47056  ? 101 EDO C H12   1 
HETATM 2761 H  HO1   . EDO U 8 .   ? -2.76990  38.23563 23.93302 1.000 43.47904  ? 101 EDO C HO1   1 
HETATM 2762 H  H21   . EDO U 8 .   ? -2.31718  38.11699 27.36018 1.000 48.04671  ? 101 EDO C H21   1 
HETATM 2763 H  H22   . EDO U 8 .   ? -3.33733  36.71102 27.67723 1.000 48.04671  ? 101 EDO C H22   1 
HETATM 2764 H  HO2   . EDO U 8 .   ? -4.06373  39.22115 27.93143 1.000 40.68858  ? 101 EDO C HO2   1 
HETATM 2765 O  O     . HOH V 9 .   ? 7.126     16.188   -4.207   1.000 52.03747  ? 401 HOH A O     1 
HETATM 2766 O  O     . HOH V 9 .   ? 3.36416   31.29697 47.92359 1.000 48.75103  ? 402 HOH A O     1 
HETATM 2767 O  O     . HOH V 9 .   ? 19.25102  2.95176  21.46695 1.000 38.15213  ? 403 HOH A O     1 
HETATM 2768 O  O     . HOH V 9 .   ? 3.62167   35.70408 54.67808 1.000 59.08284  ? 404 HOH A O     1 
HETATM 2769 O  O     . HOH V 9 .   ? 2.77763   28.34320 55.87043 1.000 35.55570  ? 405 HOH A O     1 
HETATM 2770 O  O     . HOH V 9 .   ? -4.06036  32.16295 6.51790  1.000 51.54977  ? 406 HOH A O     1 
HETATM 2771 O  O     . HOH V 9 .   ? 20.008    -2.606   29.704   1.000 39.03438  ? 407 HOH A O     1 
HETATM 2772 O  O     . HOH V 9 .   ? 12.07843  25.89501 41.74459 1.000 45.26971  ? 408 HOH A O     1 
HETATM 2773 O  O     . HOH V 9 .   ? 20.41690  15.28944 23.16985 1.000 35.15732  ? 409 HOH A O     1 
HETATM 2774 O  O     . HOH V 9 .   ? 2.10744   15.26648 30.68238 1.000 36.22758  ? 410 HOH A O     1 
HETATM 2775 O  O     . HOH V 9 .   ? -0.98661  23.79817 17.88013 1.000 28.36182  ? 411 HOH A O     1 
HETATM 2776 O  O     . HOH V 9 .   ? 10.73801  16.21456 2.08585  1.000 38.79731  ? 412 HOH A O     1 
HETATM 2777 O  O     . HOH V 9 .   ? 10.15414  7.38305  5.41610  1.000 35.95092  ? 413 HOH A O     1 
HETATM 2778 O  O     . HOH V 9 .   ? 17.44605  0.62599  23.83533 1.000 34.53100  ? 414 HOH A O     1 
HETATM 2779 O  O     . HOH V 9 .   ? 3.96618   7.67180  46.60814 1.000 39.91229  ? 415 HOH A O     1 
HETATM 2780 O  O     . HOH V 9 .   ? 3.29413   7.22842  51.13454 1.000 44.81651  ? 416 HOH A O     1 
HETATM 2781 O  O     . HOH V 9 .   ? 1.20546   23.32346 27.93982 1.000 27.73579  ? 417 HOH A O     1 
HETATM 2782 O  O     . HOH V 9 .   ? -12.37742 17.79574 7.42360  1.000 44.79140  ? 418 HOH A O     1 
HETATM 2783 O  O     . HOH V 9 .   ? -3.44766  14.34075 41.77275 1.000 38.56089  ? 419 HOH A O     1 
HETATM 2784 O  O     . HOH V 9 .   ? 18.142    -6.429   29.824   1.000 51.06164  ? 420 HOH A O     1 
HETATM 2785 O  O     . HOH V 9 .   ? -1.93623  19.05571 42.37511 1.000 26.82469  ? 421 HOH A O     1 
HETATM 2786 O  O     . HOH V 9 .   ? -1.96994  30.85669 38.59599 1.000 51.95009  ? 422 HOH A O     1 
HETATM 2787 O  O     . HOH V 9 .   ? 0.26683   24.44431 33.00532 1.000 34.61215  ? 423 HOH A O     1 
HETATM 2788 O  O     . HOH V 9 .   ? 0.92667   26.01440 -0.67006 1.000 45.13425  ? 424 HOH A O     1 
HETATM 2789 O  O     . HOH V 9 .   ? 11.03476  11.84700 18.12721 1.000 34.51007  ? 425 HOH A O     1 
HETATM 2790 O  O     . HOH V 9 .   ? 5.49545   26.57864 57.50891 1.000 33.83297  ? 426 HOH A O     1 
HETATM 2791 O  O     . HOH V 9 .   ? 3.54194   11.86266 28.71934 1.000 29.55498  ? 427 HOH A O     1 
HETATM 2792 O  O     . HOH V 9 .   ? 19.12630  1.16605  35.71741 1.000 36.43881  ? 428 HOH A O     1 
HETATM 2793 O  O     . HOH V 9 .   ? 0.26794   1.72776  10.37422 1.000 44.19459  ? 429 HOH A O     1 
HETATM 2794 O  O     . HOH V 9 .   ? 9.13655   -4.17310 35.71535 1.000 42.32919  ? 430 HOH A O     1 
HETATM 2795 O  O     . HOH V 9 .   ? 3.42032   -5.20714 18.98101 1.000 46.57446  ? 431 HOH A O     1 
HETATM 2796 O  O     . HOH V 9 .   ? -2.90712  26.03344 0.17470  1.000 39.94483  ? 432 HOH A O     1 
HETATM 2797 O  O     . HOH V 9 .   ? 4.566     11.745   64.891   1.000 49.39947  ? 433 HOH A O     1 
HETATM 2798 O  O     . HOH V 9 .   ? 14.09262  -0.96811 22.54999 1.000 38.50316  ? 434 HOH A O     1 
HETATM 2799 O  O     . HOH V 9 .   ? -7.11592  22.46612 15.61087 1.000 28.06858  ? 435 HOH A O     1 
HETATM 2800 O  O     . HOH V 9 .   ? 14.16178  11.77146 48.60866 1.000 37.18659  ? 436 HOH A O     1 
HETATM 2801 O  O     . HOH V 9 .   ? 21.79202  9.86094  17.85318 1.000 41.52609  ? 437 HOH A O     1 
HETATM 2802 O  O     . HOH V 9 .   ? 9.45810   28.30269 15.17902 1.000 30.63154  ? 438 HOH A O     1 
HETATM 2803 O  O     . HOH V 9 .   ? -2.81607  32.71090 13.23756 1.000 38.91416  ? 439 HOH A O     1 
HETATM 2804 O  O     . HOH V 9 .   ? 24.11771  10.33262 31.38297 1.000 43.66199  ? 440 HOH A O     1 
HETATM 2805 O  O     . HOH V 9 .   ? 9.52660   20.91715 15.62311 1.000 36.95929  ? 441 HOH A O     1 
HETATM 2806 O  O     . HOH V 9 .   ? 12.70778  10.22408 15.15700 1.000 32.60879  ? 442 HOH A O     1 
HETATM 2807 O  O     . HOH V 9 .   ? -1.14655  16.24974 19.95935 1.000 27.15580  ? 443 HOH A O     1 
HETATM 2808 O  O     . HOH V 9 .   ? 5.11274   4.57989  6.24777  1.000 37.75416  ? 444 HOH A O     1 
HETATM 2809 O  O     . HOH V 9 .   ? 15.18743  7.45627  7.31878  1.000 48.35434  ? 445 HOH A O     1 
HETATM 2810 O  O     . HOH V 9 .   ? -5.60538  17.05586 47.15176 1.000 38.57702  ? 446 HOH A O     1 
HETATM 2811 O  O     . HOH V 9 .   ? 20.45352  2.98468  23.84088 1.000 39.39932  ? 447 HOH A O     1 
HETATM 2812 O  O     . HOH V 9 .   ? -6.81394  7.85512  21.29374 1.000 45.38602  ? 448 HOH A O     1 
HETATM 2813 O  O     . HOH V 9 .   ? -0.41773  13.47038 7.21461  1.000 29.55750  ? 449 HOH A O     1 
HETATM 2814 O  O     . HOH V 9 .   ? 9.92369   18.96367 40.28505 1.000 32.08901  ? 450 HOH A O     1 
HETATM 2815 O  O     . HOH V 9 .   ? -0.75002  32.76388 40.79812 1.000 48.36086  ? 451 HOH A O     1 
HETATM 2816 O  O     . HOH V 9 .   ? 15.16477  -4.45935 34.23000 1.000 48.27126  ? 452 HOH A O     1 
HETATM 2817 O  O     . HOH V 9 .   ? -1.99129  10.91041 49.02754 1.000 40.73958  ? 453 HOH A O     1 
HETATM 2818 O  O     . HOH V 9 .   ? 18.08003  24.75085 2.55465  1.000 34.04391  ? 454 HOH A O     1 
HETATM 2819 O  O     . HOH V 9 .   ? 6.44030   6.21367  41.64698 1.000 48.01154  ? 455 HOH A O     1 
HETATM 2820 O  O     . HOH V 9 .   ? 19.44592  4.53436  19.07736 1.000 51.49967  ? 456 HOH A O     1 
HETATM 2821 O  O     . HOH V 9 .   ? -4.27178  7.08715  24.41198 1.000 42.33328  ? 457 HOH A O     1 
HETATM 2822 O  O     . HOH V 9 .   ? 11.23972  19.92512 35.55081 1.000 24.10699  ? 458 HOH A O     1 
HETATM 2823 O  O     . HOH V 9 .   ? 12.17274  15.03833 14.97451 1.000 36.75151  ? 459 HOH A O     1 
HETATM 2824 O  O     . HOH V 9 .   ? 11.91200  -0.89136 39.49502 1.000 50.13296  ? 460 HOH A O     1 
HETATM 2825 O  O     . HOH V 9 .   ? 20.00196  21.49461 22.16589 1.000 29.95282  ? 461 HOH A O     1 
HETATM 2826 O  O     . HOH V 9 .   ? -10.52508 25.69880 3.75740  1.000 41.10750  ? 462 HOH A O     1 
HETATM 2827 O  O     . HOH V 9 .   ? 4.00431   29.46891 44.21666 1.000 33.83783  ? 463 HOH A O     1 
HETATM 2828 O  O     . HOH V 9 .   ? 13.44523  0.41606  40.75262 1.000 51.94619  ? 464 HOH A O     1 
HETATM 2829 O  O     . HOH V 9 .   ? 15.12991  19.99445 50.83533 1.000 35.07759  ? 465 HOH A O     1 
HETATM 2830 O  O     . HOH V 9 .   ? 2.46731   15.94829 28.10806 1.000 27.72944  ? 466 HOH A O     1 
HETATM 2831 O  O     . HOH V 9 .   ? -2.41250  7.88720  16.64391 1.000 36.95119  ? 467 HOH A O     1 
HETATM 2832 O  O     . HOH V 9 .   ? 12.16996  17.51546 6.69700  1.000 25.42187  ? 468 HOH A O     1 
HETATM 2833 O  O     . HOH V 9 .   ? -14.11902 30.99621 10.01987 1.000 45.15361  ? 469 HOH A O     1 
HETATM 2834 O  O     . HOH V 9 .   ? 10.64781  22.99851 16.50667 1.000 36.34679  ? 470 HOH A O     1 
HETATM 2835 O  O     . HOH V 9 .   ? 19.78860  11.45054 10.96662 1.000 46.35671  ? 471 HOH A O     1 
HETATM 2836 O  O     . HOH V 9 .   ? -3.06540  -3.58130 18.35722 1.000 48.02739  ? 472 HOH A O     1 
HETATM 2837 O  O     . HOH V 9 .   ? -3.18962  7.78383  3.45518  1.000 41.84496  ? 473 HOH A O     1 
HETATM 2838 O  O     . HOH V 9 .   ? 16.27228  11.62188 46.56277 1.000 47.39792  ? 474 HOH A O     1 
HETATM 2839 O  O     . HOH V 9 .   ? 0.45889   29.62623 28.43371 1.000 43.53393  ? 475 HOH A O     1 
HETATM 2840 O  O     . HOH V 9 .   ? 20.18167  19.73175 7.79403  1.000 46.46663  ? 476 HOH A O     1 
HETATM 2841 O  O     . HOH V 9 .   ? -0.80937  -0.08192 14.41775 1.000 43.53876  ? 477 HOH A O     1 
HETATM 2842 O  O     . HOH V 9 .   ? 18.15105  17.60594 35.60645 1.000 30.94382  ? 478 HOH A O     1 
HETATM 2843 O  O     . HOH V 9 .   ? -3.90493  25.35161 44.80576 1.000 39.06528  ? 479 HOH A O     1 
HETATM 2844 O  O     . HOH V 9 .   ? 8.77734   14.52032 16.90996 1.000 28.43695  ? 480 HOH A O     1 
HETATM 2845 O  O     . HOH V 9 .   ? 18.59731  13.82579 30.98977 1.000 30.71726  ? 481 HOH A O     1 
HETATM 2846 O  O     . HOH V 9 .   ? -10.24328 28.48925 4.35417  1.000 46.62606  ? 482 HOH A O     1 
HETATM 2847 O  O     . HOH V 9 .   ? 7.96482   24.98143 -1.57296 1.000 35.02805  ? 483 HOH A O     1 
HETATM 2848 O  O     . HOH V 9 .   ? 23.72545  15.30318 20.23581 1.000 46.17147  ? 484 HOH A O     1 
HETATM 2849 O  O     . HOH V 9 .   ? -14.15501 29.18467 11.16677 1.000 44.44720  ? 485 HOH A O     1 
HETATM 2850 O  O     . HOH V 9 .   ? 14.83759  22.55391 29.74470 1.000 29.58453  ? 486 HOH A O     1 
HETATM 2851 O  O     . HOH V 9 .   ? 23.53342  9.16446  24.49466 1.000 41.52619  ? 487 HOH A O     1 
HETATM 2852 O  O     . HOH V 9 .   ? 13.83402  10.16359 7.10322  1.000 39.79459  ? 488 HOH A O     1 
HETATM 2853 O  O     . HOH V 9 .   ? 12.26162  24.18939 10.78454 1.000 35.38628  ? 489 HOH A O     1 
HETATM 2854 O  O     . HOH V 9 .   ? 12.73383  -0.83230 14.49743 1.000 52.86407  ? 490 HOH A O     1 
HETATM 2855 O  O     . HOH V 9 .   ? 12.83904  28.45265 10.14051 1.000 49.01973  ? 491 HOH A O     1 
HETATM 2856 O  O     . HOH V 9 .   ? -5.06801  26.17486 47.06945 1.000 43.49630  ? 492 HOH A O     1 
HETATM 2857 O  O     . HOH V 9 .   ? 0.27695   -2.55295 25.42528 1.000 48.21036  ? 493 HOH A O     1 
HETATM 2858 O  O     . HOH V 9 .   ? 10.09761  28.98403 56.59603 1.000 41.83936  ? 494 HOH A O     1 
HETATM 2859 O  O     . HOH V 9 .   ? 11.89971  14.85333 5.81248  1.000 28.63635  ? 495 HOH A O     1 
HETATM 2860 O  O     . HOH V 9 .   ? 14.78943  24.03763 15.45428 1.000 46.80648  ? 496 HOH A O     1 
HETATM 2861 O  O     . HOH V 9 .   ? -0.68905  15.83537 52.98839 1.000 37.94521  ? 497 HOH A O     1 
HETATM 2862 O  O     . HOH V 9 .   ? -1.71959  12.21785 16.69691 1.000 26.63249  ? 498 HOH A O     1 
HETATM 2863 O  O     . HOH V 9 .   ? 3.93287   13.56372 20.84640 1.000 38.58637  ? 499 HOH A O     1 
HETATM 2864 O  O     . HOH V 9 .   ? 18.50444  6.57370  44.05430 1.000 49.37822  ? 500 HOH A O     1 
HETATM 2865 O  O     . HOH V 9 .   ? 20.00406  27.39667 24.38434 1.000 45.33877  ? 501 HOH A O     1 
HETATM 2866 O  O     . HOH V 9 .   ? -0.94341  15.78232 33.20727 1.000 37.65654  ? 502 HOH A O     1 
HETATM 2867 O  O     . HOH V 9 .   ? -0.81716  25.74486 38.54248 1.000 27.62202  ? 503 HOH A O     1 
HETATM 2868 O  O     . HOH V 9 .   ? 0.53546   6.15818  -0.08695 1.000 48.28327  ? 504 HOH A O     1 
HETATM 2869 O  O     . HOH V 9 .   ? 3.28338   16.88491 34.85121 1.000 24.40679  ? 505 HOH A O     1 
HETATM 2870 O  O     . HOH V 9 .   ? -5.17873  1.52955  23.52662 1.000 56.64439  ? 506 HOH A O     1 
HETATM 2871 O  O     . HOH V 9 .   ? 9.75256   30.40180 3.41663  1.000 51.10506  ? 507 HOH A O     1 
HETATM 2872 O  O     . HOH V 9 .   ? 21.785    15.520   26.692   1.000 30.82763  ? 508 HOH A O     1 
HETATM 2873 O  O     . HOH V 9 .   ? -1.60013  23.85618 -0.33844 1.000 45.09814  ? 509 HOH A O     1 
HETATM 2874 O  O     . HOH V 9 .   ? 2.24121   6.41474  12.47560 1.000 28.12723  ? 510 HOH A O     1 
HETATM 2875 O  O     . HOH V 9 .   ? 0.38359   4.79987  13.80695 1.000 31.22653  ? 511 HOH A O     1 
HETATM 2876 O  O     . HOH V 9 .   ? 11.44169  -2.03048 21.71398 1.000 43.98765  ? 512 HOH A O     1 
HETATM 2877 O  O     . HOH V 9 .   ? -4.80121  23.21304 24.32227 1.000 47.78340  ? 513 HOH A O     1 
HETATM 2878 O  O     . HOH V 9 .   ? 13.78093  7.74664  14.30415 1.000 36.56563  ? 514 HOH A O     1 
HETATM 2879 O  O     . HOH V 9 .   ? 5.45310   9.94540  29.65889 1.000 33.12302  ? 515 HOH A O     1 
HETATM 2880 O  O     . HOH V 9 .   ? 23.68829  11.04206 19.52086 1.000 39.36038  ? 516 HOH A O     1 
HETATM 2881 O  O     . HOH V 9 .   ? -9.27113  9.99462  5.95690  1.000 46.48215  ? 517 HOH A O     1 
HETATM 2882 O  O     . HOH V 9 .   ? 14.62128  24.47622 9.52200  1.000 33.55033  ? 518 HOH A O     1 
HETATM 2883 O  O     . HOH V 9 .   ? 3.13437   34.30882 15.79629 1.000 37.04853  ? 519 HOH A O     1 
HETATM 2884 O  O     . HOH V 9 .   ? -6.71770  26.78644 2.70714  1.000 36.29794  ? 520 HOH A O     1 
HETATM 2885 O  O     . HOH V 9 .   ? 18.19343  23.09770 8.63071  1.000 42.37431  ? 521 HOH A O     1 
HETATM 2886 O  O     . HOH V 9 .   ? -2.60161  6.78070  14.05375 1.000 41.17474  ? 522 HOH A O     1 
HETATM 2887 O  O     . HOH V 9 .   ? 16.33761  18.58547 43.76447 1.000 36.76386  ? 523 HOH A O     1 
HETATM 2888 O  O     . HOH V 9 .   ? -4.71053  16.63575 37.80822 1.000 42.25296  ? 524 HOH A O     1 
HETATM 2889 O  O     . HOH V 9 .   ? 4.07910   33.95108 35.80874 1.000 44.41429  ? 525 HOH A O     1 
HETATM 2890 O  O     . HOH V 9 .   ? -11.69576 18.05358 17.90417 1.000 38.22930  ? 526 HOH A O     1 
HETATM 2891 O  O     . HOH V 9 .   ? 8.70919   4.29548  42.96602 1.000 53.72892  ? 527 HOH A O     1 
HETATM 2892 O  O     . HOH V 9 .   ? -3.22499  -0.30917 16.13904 1.000 44.47645  ? 528 HOH A O     1 
HETATM 2893 O  O     . HOH V 9 .   ? 16.12779  6.07299  45.54652 1.000 45.33217  ? 529 HOH A O     1 
HETATM 2894 O  O     . HOH V 9 .   ? -6.30367  7.47317  18.38348 1.000 49.81257  ? 530 HOH A O     1 
HETATM 2895 O  O     . HOH V 9 .   ? 4.49233   25.44541 53.19935 1.000 36.85224  ? 531 HOH A O     1 
HETATM 2896 O  O     . HOH V 9 .   ? 4.89091   30.96844 16.89162 1.000 33.17162  ? 532 HOH A O     1 
HETATM 2897 O  O     . HOH V 9 .   ? -3.37033  13.98613 18.19831 1.000 33.21771  ? 533 HOH A O     1 
HETATM 2898 O  O     . HOH V 9 .   ? 0.76419   36.08481 9.11259  1.000 49.16089  ? 534 HOH A O     1 
HETATM 2899 O  O     . HOH V 9 .   ? -2.13592  18.46358 20.89643 1.000 29.31997  ? 535 HOH A O     1 
HETATM 2900 O  O     . HOH V 9 .   ? -2.53304  29.47524 43.19329 1.000 49.28135  ? 536 HOH A O     1 
HETATM 2901 O  O     . HOH V 9 .   ? 1.77017   10.39611 37.94820 1.000 43.94824  ? 537 HOH A O     1 
HETATM 2902 O  O     . HOH V 9 .   ? -0.01021  10.84827 0.20322  1.000 45.15352  ? 538 HOH A O     1 
HETATM 2903 O  O     . HOH V 9 .   ? 11.51557  27.96102 3.10303  1.000 43.15219  ? 539 HOH A O     1 
HETATM 2904 O  O     . HOH V 9 .   ? 3.65728   -4.79368 35.60414 1.000 56.44915  ? 540 HOH A O     1 
HETATM 2905 O  O     . HOH V 9 .   ? -5.77033  23.23353 47.75016 1.000 37.81053  ? 541 HOH A O     1 
HETATM 2906 O  O     . HOH V 9 .   ? 22.03272  25.14797 29.06276 1.000 45.28028  ? 542 HOH A O     1 
HETATM 2907 O  O     . HOH V 9 .   ? 2.24104   9.88441  35.54382 1.000 41.83976  ? 543 HOH A O     1 
HETATM 2908 O  O     . HOH V 9 .   ? 24.58693  17.04661 32.97214 1.000 48.47250  ? 544 HOH A O     1 
HETATM 2909 O  O     . HOH V 9 .   ? -5.00381  13.18052 46.30872 1.000 48.72726  ? 545 HOH A O     1 
HETATM 2910 O  O     . HOH V 9 .   ? -1.71983  5.98709  5.29711  1.000 52.03909  ? 546 HOH A O     1 
HETATM 2911 O  O     . HOH V 9 .   ? 21.85050  18.18250 21.15988 1.000 45.38758  ? 547 HOH A O     1 
HETATM 2912 O  O     . HOH V 9 .   ? 3.33210   33.24810 33.75656 1.000 48.86520  ? 548 HOH A O     1 
HETATM 2913 O  O     . HOH V 9 .   ? 2.05749   38.15314 19.66964 1.000 50.64694  ? 549 HOH A O     1 
HETATM 2914 O  O     . HOH V 9 .   ? 13.79844  25.10065 20.06597 1.000 34.08519  ? 550 HOH A O     1 
HETATM 2915 O  O     . HOH V 9 .   ? -4.46397  18.96388 22.23151 1.000 36.58651  ? 551 HOH A O     1 
HETATM 2916 O  O     . HOH V 9 .   ? 15.26026  -2.68008 40.45684 1.000 51.87778  ? 552 HOH A O     1 
HETATM 2917 O  O     . HOH V 9 .   ? 0.736     17.599   -4.287   1.000 39.41920  ? 553 HOH A O     1 
HETATM 2918 O  O     . HOH V 9 .   ? 18.83074  3.22491  16.82626 1.000 45.98379  ? 554 HOH A O     1 
HETATM 2919 O  O     . HOH V 9 .   ? -1.42264  27.67437 45.01236 1.000 40.16939  ? 555 HOH A O     1 
HETATM 2920 O  O     . HOH V 9 .   ? -4.37538  32.74567 34.97133 1.000 58.64012  ? 556 HOH A O     1 
HETATM 2921 O  O     . HOH V 9 .   ? 10.11383  27.69883 40.94984 1.000 47.30196  ? 557 HOH A O     1 
HETATM 2922 O  O     . HOH V 9 .   ? 11.41915  1.32139  40.56286 1.000 53.01091  ? 558 HOH A O     1 
HETATM 2923 O  O     . HOH V 9 .   ? 9.70808   27.28130 19.50174 1.000 33.60428  ? 559 HOH A O     1 
HETATM 2924 O  O     . HOH V 9 .   ? 11.09690  16.24813 16.60891 1.000 39.34901  ? 560 HOH A O     1 
HETATM 2925 O  O     . HOH V 9 .   ? 14.14949  -9.71431 24.28986 1.000 55.06952  ? 561 HOH A O     1 
HETATM 2926 O  O     . HOH V 9 .   ? 0.242     31.156   55.619   1.000 53.00698  ? 562 HOH A O     1 
HETATM 2927 O  O     . HOH V 9 .   ? 9.68067   32.40796 4.37169  1.000 53.94982  ? 563 HOH A O     1 
HETATM 2928 O  O     . HOH V 9 .   ? 15.25297  22.65529 38.11111 1.000 48.21316  ? 564 HOH A O     1 
HETATM 2929 O  O     . HOH V 9 .   ? -2.984    33.294   24.015   1.000 55.54740  ? 565 HOH A O     1 
HETATM 2930 O  O     . HOH V 9 .   ? -4.50797  12.89842 43.44999 1.000 45.58950  ? 566 HOH A O     1 
HETATM 2931 O  O     . HOH V 9 .   ? 2.48808   31.15120 32.12985 1.000 53.66081  ? 567 HOH A O     1 
HETATM 2932 O  O     . HOH V 9 .   ? -2.68170  6.66040  7.48041  1.000 48.65279  ? 568 HOH A O     1 
HETATM 2933 O  O     . HOH V 9 .   ? 9.90635   31.25328 55.90373 1.000 51.31669  ? 569 HOH A O     1 
HETATM 2934 O  O     . HOH V 9 .   ? -2.63816  4.39127  13.26387 1.000 43.60911  ? 570 HOH A O     1 
HETATM 2935 O  O     . HOH V 9 .   ? 19.23573  2.50499  41.25075 1.000 48.25031  ? 571 HOH A O     1 
HETATM 2936 O  O     . HOH V 9 .   ? 18.51018  11.32412 43.13497 1.000 51.96473  ? 572 HOH A O     1 
HETATM 2937 O  O     . HOH V 9 .   ? -7.30017  22.86544 49.90051 1.000 49.45956  ? 573 HOH A O     1 
HETATM 2938 O  O     . HOH V 9 .   ? -1.897    27.299   -3.677   1.000 55.11392  ? 574 HOH A O     1 
HETATM 2939 O  O     . HOH V 9 .   ? 18.41577  16.79408 44.20338 1.000 48.04722  ? 575 HOH A O     1 
HETATM 2940 O  O     . HOH V 9 .   ? 11.83338  25.57317 16.14864 1.000 48.33650  ? 576 HOH A O     1 
HETATM 2941 O  O     . HOH V 9 .   ? 15.493    -7.358   33.421   1.000 55.49375  ? 577 HOH A O     1 
HETATM 2942 O  O     . HOH V 9 .   ? 6.457     15.781   63.384   1.000 45.11435  ? 578 HOH A O     1 
HETATM 2943 O  O     . HOH V 9 .   ? 12.86329  15.48194 3.39651  1.000 42.17278  ? 579 HOH A O     1 
HETATM 2944 O  O     . HOH V 9 .   ? 10.88018  12.74407 15.79155 1.000 35.79178  ? 580 HOH A O     1 
HETATM 2945 O  O     . HOH V 9 .   ? 16.64634  27.07105 2.15772  1.000 48.58328  ? 581 HOH A O     1 
HETATM 2946 O  O     . HOH V 9 .   ? 1.97503   31.04227 56.35944 1.000 49.57822  ? 582 HOH A O     1 
HETATM 2947 O  O     . HOH V 9 .   ? 12.98499  7.61911  6.23926  1.000 45.41021  ? 583 HOH A O     1 
HETATM 2948 O  O     . HOH V 9 .   ? -3.62305  5.43188  9.28858  1.000 53.86117  ? 584 HOH A O     1 
HETATM 2949 O  O     . HOH V 9 .   ? 19.01845  19.75363 19.22284 1.000 42.76115  ? 585 HOH A O     1 
HETATM 2950 O  O     . HOH V 9 .   ? 8.15553   27.87892 58.76301 1.000 50.60358  ? 586 HOH A O     1 
HETATM 2951 O  O     . HOH V 9 .   ? -5.442    29.300   -5.911   1.000 35.90790  ? 587 HOH A O     1 
HETATM 2952 O  O     . HOH V 9 .   ? -16.326   35.566   16.182   1.000 54.98038  ? 588 HOH A O     1 
HETATM 2953 O  O     . HOH V 9 .   ? 12.74314  25.95110 12.84451 1.000 46.46821  ? 589 HOH A O     1 
HETATM 2954 O  O     . HOH V 9 .   ? 19.89231  3.65271  37.19592 1.000 42.60547  ? 590 HOH A O     1 
HETATM 2955 O  O     . HOH V 9 .   ? 18.86389  21.62112 19.14235 1.000 44.09167  ? 591 HOH A O     1 
HETATM 2956 O  O     . HOH V 9 .   ? 3.01180   6.03621  48.45051 1.000 44.18646  ? 592 HOH A O     1 
HETATM 2957 O  O     . HOH V 9 .   ? -3.860    26.199   -2.815   1.000 48.18419  ? 593 HOH A O     1 
HETATM 2958 O  O     . HOH V 9 .   ? 16.56734  21.63092 49.73682 1.000 47.36236  ? 594 HOH A O     1 
HETATM 2959 O  O     . HOH V 9 .   ? 12.18832  32.82258 55.21792 1.000 57.60068  ? 595 HOH A O     1 
HETATM 2960 O  O     . HOH V 9 .   ? -4.44435  34.46126 14.40328 1.000 47.08317  ? 596 HOH A O     1 
HETATM 2961 O  O     . HOH V 9 .   ? -4.88260  26.13401 41.87198 1.000 53.52019  ? 597 HOH A O     1 
HETATM 2962 O  O     . HOH W 9 .   ? 17.06483  31.82284 22.39482 1.000 47.37986  ? 201 HOH B O     1 
HETATM 2963 O  O     . HOH W 9 .   ? -7.69111  20.06207 25.63598 1.000 51.18972  ? 202 HOH B O     1 
HETATM 2964 O  O     . HOH W 9 .   ? 12.95335  30.02039 34.27613 1.000 45.08819  ? 203 HOH B O     1 
HETATM 2965 O  O     . HOH W 9 .   ? 10.22054  30.33424 20.60214 1.000 39.59055  ? 204 HOH B O     1 
HETATM 2966 O  O     . HOH W 9 .   ? -1.91809  23.75190 37.21356 1.000 34.18260  ? 205 HOH B O     1 
HETATM 2967 O  O     . HOH W 9 .   ? 11.84526  26.83208 25.70883 1.000 31.23701  ? 206 HOH B O     1 
HETATM 2968 O  O     . HOH W 9 .   ? 15.55094  33.08063 26.02483 1.000 46.34643  ? 207 HOH B O     1 
HETATM 2969 O  O     . HOH W 9 .   ? 17.18283  23.58935 29.28226 1.000 36.42429  ? 208 HOH B O     1 
HETATM 2970 O  O     . HOH W 9 .   ? -12.63518 11.04789 27.36151 1.000 47.37394  ? 209 HOH B O     1 
HETATM 2971 O  O     . HOH W 9 .   ? 11.01604  32.92844 30.10969 1.000 38.04966  ? 210 HOH B O     1 
HETATM 2972 O  O     . HOH W 9 .   ? -4.26780  17.02372 35.14538 1.000 32.42671  ? 211 HOH B O     1 
HETATM 2973 O  O     . HOH W 9 .   ? 16.49688  24.23966 34.39181 1.000 38.80192  ? 212 HOH B O     1 
HETATM 2974 O  O     . HOH W 9 .   ? 8.58097   25.57702 40.32178 1.000 32.11119  ? 213 HOH B O     1 
HETATM 2975 O  O     . HOH W 9 .   ? 2.44484   29.34941 30.44369 1.000 42.50848  ? 214 HOH B O     1 
HETATM 2976 O  O     . HOH W 9 .   ? 13.58987  24.26807 37.13283 1.000 40.90659  ? 215 HOH B O     1 
HETATM 2977 O  O     . HOH W 9 .   ? 8.11431   36.83465 20.80787 1.000 45.10756  ? 216 HOH B O     1 
HETATM 2978 O  O     . HOH W 9 .   ? 8.90439   33.70740 20.04010 1.000 38.39956  ? 217 HOH B O     1 
HETATM 2979 O  O     . HOH W 9 .   ? 13.03871  32.13814 29.86021 1.000 45.30055  ? 218 HOH B O     1 
HETATM 2980 O  O     . HOH W 9 .   ? 1.50360   16.72514 32.78963 1.000 31.66474  ? 219 HOH B O     1 
HETATM 2981 O  O     . HOH W 9 .   ? 10.60065  26.74486 37.74842 1.000 37.56577  ? 220 HOH B O     1 
HETATM 2982 O  O     . HOH W 9 .   ? -4.51376  24.38389 39.75742 1.000 38.80187  ? 221 HOH B O     1 
HETATM 2983 O  O     . HOH W 9 .   ? -13.18658 14.19411 32.75220 1.000 49.36108  ? 222 HOH B O     1 
HETATM 2984 O  O     . HOH W 9 .   ? -16.75602 22.53463 22.47573 1.000 41.89278  ? 223 HOH B O     1 
HETATM 2985 O  O     . HOH W 9 .   ? 6.90561   31.10417 32.51467 1.000 48.24559  ? 224 HOH B O     1 
HETATM 2986 O  O     . HOH W 9 .   ? 14.20939  34.03943 27.93563 1.000 49.52181  ? 225 HOH B O     1 
HETATM 2987 O  O     . HOH W 9 .   ? -4.90769  22.91117 27.73988 1.000 42.95190  ? 226 HOH B O     1 
HETATM 2988 O  O     . HOH W 9 .   ? -5.41571  24.07918 29.75643 1.000 41.06632  ? 227 HOH B O     1 
HETATM 2989 O  O     . HOH W 9 .   ? -8.65585  18.11323 24.43420 1.000 52.56804  ? 228 HOH B O     1 
HETATM 2990 O  O     . HOH W 9 .   ? 9.04194   30.62204 33.60336 1.000 42.60015  ? 229 HOH B O     1 
HETATM 2991 O  O     . HOH W 9 .   ? -3.58622  25.13940 30.42487 1.000 44.66139  ? 230 HOH B O     1 
HETATM 2992 O  O     . HOH W 9 .   ? -12.577   10.431   30.006   1.000 49.58926  ? 231 HOH B O     1 
HETATM 2993 O  O     . HOH W 9 .   ? -10.96385 18.88123 23.00764 1.000 56.11117  ? 232 HOH B O     1 
HETATM 2994 O  O     . HOH X 9 .   ? -3.96167  8.99932  26.06025 1.000 47.41593  ? 201 HOH C O     1 
HETATM 2995 O  O     . HOH X 9 .   ? -9.03954  13.53595 25.20102 1.000 51.82035  ? 202 HOH C O     1 
HETATM 2996 O  O     . HOH X 9 .   ? -3.20615  22.57741 26.12142 1.000 38.85394  ? 203 HOH C O     1 
HETATM 2997 O  O     . HOH X 9 .   ? 0.35358   36.76968 28.87778 1.000 41.66627  ? 204 HOH C O     1 
HETATM 2998 O  O     . HOH X 9 .   ? 1.11150   24.17106 22.10428 1.000 34.85217  ? 205 HOH C O     1 
HETATM 2999 O  O     . HOH X 9 .   ? 11.34272  24.73105 18.85182 1.000 37.52738  ? 206 HOH C O     1 
HETATM 3000 O  O     . HOH X 9 .   ? 11.19018  35.42305 30.01623 1.000 48.26173  ? 207 HOH C O     1 
HETATM 3001 O  O     . HOH X 9 .   ? -0.31021  20.28224 20.62313 1.000 26.19226  ? 208 HOH C O     1 
HETATM 3002 O  O     . HOH X 9 .   ? 9.67374   18.42576 17.19700 1.000 36.38755  ? 209 HOH C O     1 
HETATM 3003 O  O     . HOH X 9 .   ? 7.58969   24.52402 16.66469 1.000 28.64574  ? 210 HOH C O     1 
HETATM 3004 O  O     . HOH X 9 .   ? 3.00380   42.70229 32.32677 1.000 40.27694  ? 211 HOH C O     1 
HETATM 3005 O  O     . HOH X 9 .   ? -2.59144  14.25746 20.93768 1.000 32.33780  ? 212 HOH C O     1 
HETATM 3006 O  O     . HOH X 9 .   ? -7.02839  15.17741 24.11807 1.000 47.47973  ? 213 HOH C O     1 
HETATM 3007 O  O     . HOH X 9 .   ? 6.80851   32.08003 20.90189 1.000 33.80779  ? 214 HOH C O     1 
HETATM 3008 O  O     . HOH X 9 .   ? 0.39311   27.04539 19.24331 1.000 29.72319  ? 215 HOH C O     1 
HETATM 3009 O  O     . HOH X 9 .   ? 5.95592   36.37988 21.88503 1.000 33.67544  ? 216 HOH C O     1 
HETATM 3010 O  O     . HOH X 9 .   ? 7.60144   27.84619 22.44289 1.000 26.78491  ? 217 HOH C O     1 
HETATM 3011 O  O     . HOH X 9 .   ? 10.07027  24.60502 25.54213 1.000 25.27943  ? 218 HOH C O     1 
HETATM 3012 O  O     . HOH X 9 .   ? 5.62024   28.81766 18.13752 1.000 27.85386  ? 219 HOH C O     1 
HETATM 3013 O  O     . HOH X 9 .   ? -1.96158  34.01579 21.89987 1.000 46.66211  ? 220 HOH C O     1 
HETATM 3014 O  O     . HOH X 9 .   ? -2.49738  14.19564 32.59093 1.000 40.33279  ? 221 HOH C O     1 
HETATM 3015 O  O     . HOH X 9 .   ? 1.10132   25.20162 24.71577 1.000 30.49320  ? 222 HOH C O     1 
HETATM 3016 O  O     . HOH X 9 .   ? -4.65183  20.15609 24.86110 1.000 39.38524  ? 223 HOH C O     1 
HETATM 3017 O  O     . HOH X 9 .   ? -1.54827  22.53746 24.66865 1.000 37.76975  ? 224 HOH C O     1 
HETATM 3018 O  O     . HOH X 9 .   ? -4.146    41.032   24.934   1.000 31.83345  ? 225 HOH C O     1 
HETATM 3019 O  O     . HOH X 9 .   ? 3.42409   33.05394 18.08368 1.000 35.65196  ? 226 HOH C O     1 
HETATM 3020 O  O     . HOH X 9 .   ? 0.00301   30.58998 24.30219 1.000 38.56596  ? 227 HOH C O     1 
HETATM 3021 O  O     . HOH X 9 .   ? 0.08122   40.51768 22.78712 1.000 46.76739  ? 228 HOH C O     1 
HETATM 3022 O  O     . HOH X 9 .   ? 6.02621   33.81489 30.61710 1.000 39.97872  ? 229 HOH C O     1 
HETATM 3023 O  O     . HOH X 9 .   ? -3.49071  13.03611 23.98194 1.000 36.60909  ? 230 HOH C O     1 
HETATM 3024 O  O     . HOH X 9 .   ? 1.08033   27.21553 26.71356 1.000 32.47272  ? 231 HOH C O     1 
HETATM 3025 O  O     . HOH X 9 .   ? 3.86120   36.11522 30.12490 1.000 45.40800  ? 232 HOH C O     1 
HETATM 3026 O  O     . HOH X 9 .   ? 2.87259   32.57592 29.83713 1.000 42.14195  ? 233 HOH C O     1 
HETATM 3027 O  O     . HOH X 9 .   ? -0.92393  22.27982 22.69212 1.000 49.47560  ? 234 HOH C O     1 
HETATM 3028 O  O     . HOH X 9 .   ? 7.38147   29.52366 20.28325 1.000 33.74238  ? 235 HOH C O     1 
HETATM 3029 O  O     . HOH X 9 .   ? 5.22718   34.42811 19.83230 1.000 41.54742  ? 236 HOH C O     1 
HETATM 3030 O  O     . HOH X 9 .   ? 2.94114   42.21522 23.77694 1.000 45.17073  ? 237 HOH C O     1 
HETATM 3031 O  O     . HOH X 9 .   ? -4.94691  11.31066 24.96122 1.000 42.92104  ? 238 HOH C O     1 
HETATM 3032 O  O     . HOH X 9 .   ? -5.17312  14.41291 22.25557 1.000 42.85261  ? 239 HOH C O     1 
HETATM 3033 O  O     . HOH X 9 .   ? 7.95295   27.13368 17.26460 1.000 30.35535  ? 240 HOH C O     1 
# 
loop_
_atom_site_anisotrop.id 
_atom_site_anisotrop.type_symbol 
_atom_site_anisotrop.pdbx_label_atom_id 
_atom_site_anisotrop.pdbx_label_alt_id 
_atom_site_anisotrop.pdbx_label_comp_id 
_atom_site_anisotrop.pdbx_label_asym_id 
_atom_site_anisotrop.pdbx_label_seq_id 
_atom_site_anisotrop.pdbx_PDB_ins_code 
_atom_site_anisotrop.U[1][1] 
_atom_site_anisotrop.U[2][2] 
_atom_site_anisotrop.U[3][3] 
_atom_site_anisotrop.U[1][2] 
_atom_site_anisotrop.U[1][3] 
_atom_site_anisotrop.U[2][3] 
_atom_site_anisotrop.pdbx_auth_seq_id 
_atom_site_anisotrop.pdbx_auth_comp_id 
_atom_site_anisotrop.pdbx_auth_asym_id 
_atom_site_anisotrop.pdbx_auth_atom_id 
11   N N     . MET A 3   ? 0.66884 0.75342 0.54133 0.03458  -0.03895 0.10502  1   MET A N     
12   C CA    . MET A 3   ? 0.54242 0.63826 0.41757 0.03363  -0.03337 0.09053  1   MET A CA    
13   C C     . MET A 3   ? 0.50889 0.60324 0.39623 0.03587  -0.03940 0.07521  1   MET A C     
14   O O     . MET A 3   ? 0.56552 0.65028 0.46808 0.03588  -0.04261 0.07517  1   MET A O     
15   C CB    . MET A 3   ? 0.59134 0.68509 0.47656 0.02700  -0.02361 0.09229  1   MET A CB    
16   C CG    . MET A 3   ? 0.62425 0.72977 0.50794 0.02848  -0.01652 0.08011  1   MET A CG    
17   S SD    . MET A 3   ? 0.64147 0.75726 0.52968 0.02229  -0.00426 0.09018  1   MET A SD    
18   C CE    . MET A 3   ? 0.52113 0.61804 0.42029 0.01269  -0.00839 0.10567  1   MET A CE    
19   N N     . ALA A 4   ? 0.53157 0.63485 0.41082 0.03742  -0.04099 0.06245  2   ALA A N     
20   C CA    . ALA A 4   ? 0.46202 0.56385 0.35244 0.03587  -0.04605 0.04820  2   ALA A CA    
21   C C     . ALA A 4   ? 0.47894 0.57182 0.38540 0.03189  -0.03908 0.04287  2   ALA A C     
22   O O     . ALA A 4   ? 0.40701 0.49793 0.31315 0.03075  -0.03021 0.04678  2   ALA A O     
23   C CB    . ALA A 4   ? 0.41820 0.52552 0.29197 0.03656  -0.05015 0.03567  2   ALA A CB    
24   N N     . PHE A 5   ? 0.41355 0.50392 0.33419 0.02939  -0.04344 0.03435  3   PHE A N     
25   C CA    . PHE A 5   ? 0.39496 0.47671 0.33261 0.02623  -0.03820 0.03155  3   PHE A CA    
26   C C     . PHE A 5   ? 0.35850 0.43592 0.29150 0.02503  -0.03018 0.02508  3   PHE A C     
27   O O     . PHE A 5   ? 0.33870 0.41255 0.27893 0.02400  -0.02289 0.02963  3   PHE A O     
28   C CB    . PHE A 5   ? 0.32229 0.40626 0.27391 0.02360  -0.04436 0.02428  3   PHE A CB    
29   C CG    . PHE A 5   ? 0.31339 0.38937 0.28048 0.02062  -0.03920 0.02085  3   PHE A CG    
30   C CD1   . PHE A 5   ? 0.32192 0.39161 0.29927 0.02263  -0.03558 0.02820  3   PHE A CD1   
31   C CD2   . PHE A 5   ? 0.31046 0.38249 0.27927 0.01580  -0.03870 0.01041  3   PHE A CD2   
32   C CE1   . PHE A 5   ? 0.31883 0.38163 0.30869 0.02031  -0.03123 0.02485  3   PHE A CE1   
33   C CE2   . PHE A 5   ? 0.29500 0.36009 0.27695 0.01345  -0.03398 0.00819  3   PHE A CE2   
34   C CZ    . PHE A 5   ? 0.30630 0.36844 0.29919 0.01593  -0.03009 0.01522  3   PHE A CZ    
35   N N     . VAL A 6   ? 0.34564 0.42228 0.26605 0.02551  -0.03223 0.01399  4   VAL A N     
36   C CA    . VAL A 6   ? 0.35906 0.42927 0.27409 0.02734  -0.02514 0.00671  4   VAL A CA    
37   C C     . VAL A 6   ? 0.43043 0.50948 0.33717 0.03230  -0.01596 0.01473  4   VAL A C     
38   O O     . VAL A 6   ? 0.40351 0.48306 0.31542 0.03371  -0.00800 0.01501  4   VAL A O     
39   C CB    . VAL A 6   ? 0.45473 0.51650 0.35247 0.02810  -0.03051 -0.00729 4   VAL A CB    
40   C CG1   . VAL A 6   ? 0.49973 0.55479 0.38488 0.03518  -0.02250 -0.01373 4   VAL A CG1   
41   C CG2   . VAL A 6   ? 0.45191 0.50530 0.36128 0.01992  -0.03800 -0.01426 4   VAL A CG2   
42   N N     . GLU A 7   ? 0.39814 0.48706 0.29232 0.03469  -0.01701 0.02242  5   GLU A N     
43   C CA    . GLU A 7   ? 0.39492 0.49678 0.28114 0.03787  -0.00815 0.03234  5   GLU A CA    
44   C C     . GLU A 7   ? 0.43967 0.54299 0.34328 0.03141  -0.00392 0.04602  5   GLU A C     
45   O O     . GLU A 7   ? 0.41074 0.52435 0.31680 0.03087  0.00461  0.05205  5   GLU A O     
46   C CB    . GLU A 7   ? 0.46194 0.57346 0.32851 0.04136  -0.01104 0.03792  5   GLU A CB    
47   C CG    . GLU A 7   ? 0.63272 0.74335 0.47605 0.04855  -0.01437 0.02427  5   GLU A CG    
48   C CD    . GLU A 7   ? 0.76373 0.87977 0.59452 0.05727  -0.00470 0.01837  5   GLU A CD    
49   O OE1   . GLU A 7   ? 0.78542 0.91974 0.61332 0.06023  0.00467  0.02970  5   GLU A OE1   
50   O OE2   . GLU A 7   ? 0.83479 0.93714 0.65863 0.06129  -0.00646 0.00321  5   GLU A OE2   
51   N N     . ARG A 8   ? 0.36494 0.45846 0.27966 0.02679  -0.01029 0.05115  6   ARG A N     
52   C CA    . ARG A 8   ? 0.38910 0.47662 0.31769 0.02044  -0.00810 0.06181  6   ARG A CA    
53   C C     . ARG A 8   ? 0.39110 0.47608 0.33346 0.01822  -0.00300 0.05557  6   ARG A C     
54   O O     . ARG A 8   ? 0.38960 0.47931 0.33794 0.01339  0.00246  0.06352  6   ARG A O     
55   C CB    . ARG A 8   ? 0.42097 0.49481 0.35625 0.01970  -0.01644 0.06525  6   ARG A CB    
56   C CG    . ARG A 8   ? 0.44752 0.50746 0.39543 0.01453  -0.01612 0.07137  6   ARG A CG    
57   C CD    . ARG A 8   ? 0.48169 0.53997 0.42317 0.00807  -0.01388 0.08751  6   ARG A CD    
58   N NE    . ARG A 8   ? 0.64050 0.69113 0.57045 0.01052  -0.02029 0.09727  6   ARG A NE    
59   C CZ    . ARG A 8   ? 0.69368 0.74188 0.61315 0.00499  -0.01992 0.11299  6   ARG A CZ    
60   N NH1   . ARG A 8   ? 0.59154 0.64884 0.51198 -0.00453 -0.01315 0.12133  6   ARG A NH1   
61   N NH2   . ARG A 8   ? 0.69043 0.72856 0.59820 0.00886  -0.02670 0.12157  6   ARG A NH2   
62   N N     . VAL A 9   ? 0.34299 0.42116 0.29043 0.02066  -0.00541 0.04222  7   VAL A N     
63   C CA    . VAL A 9   ? 0.33741 0.41165 0.29663 0.01938  -0.00127 0.03642  7   VAL A CA    
64   C C     . VAL A 9   ? 0.34304 0.42971 0.29589 0.02341  0.00698  0.03530  7   VAL A C     
65   O O     . VAL A 9   ? 0.32883 0.42117 0.29136 0.02087  0.01224  0.03971  7   VAL A O     
66   C CB    . VAL A 9   ? 0.31888 0.38299 0.28273 0.02020  -0.00597 0.02395  7   VAL A CB    
67   C CG1   . VAL A 9   ? 0.32902 0.38837 0.30245 0.01970  -0.00136 0.01859  7   VAL A CG1   
68   C CG2   . VAL A 9   ? 0.33337 0.39156 0.30674 0.01776  -0.01285 0.02636  7   VAL A CG2   
69   N N     A ARG A 10  ? 0.37215 0.46420 0.30780 0.03073  0.00788  0.02906  8   ARG A N     
70   N N     B ARG A 10  ? 0.37210 0.46436 0.30761 0.03070  0.00789  0.02928  8   ARG A N     
71   C CA    A ARG A 10  ? 0.38825 0.49291 0.31595 0.03849  0.01622  0.02682  8   ARG A CA    
72   C CA    B ARG A 10  ? 0.38854 0.49311 0.31565 0.03867  0.01611  0.02661  8   ARG A CA    
73   C C     A ARG A 10  ? 0.37919 0.50629 0.31021 0.03573  0.02341  0.04207  8   ARG A C     
74   C C     B ARG A 10  ? 0.37952 0.50706 0.30918 0.03647  0.02355  0.04160  8   ARG A C     
75   O O     A ARG A 10  ? 0.37547 0.51601 0.31442 0.03691  0.03026  0.04501  8   ARG A O     
76   O O     B ARG A 10  ? 0.37634 0.51835 0.31184 0.03908  0.03086  0.04382  8   ARG A O     
77   C CB    A ARG A 10  ? 0.44529 0.54805 0.34936 0.04851  0.01503  0.01626  8   ARG A CB    
78   C CB    B ARG A 10  ? 0.44594 0.54766 0.34950 0.04844  0.01448  0.01569  8   ARG A CB    
79   C CG    A ARG A 10  ? 0.48351 0.56394 0.38299 0.05068  0.00935  0.00051  8   ARG A CG    
80   C CG    B ARG A 10  ? 0.48566 0.56438 0.38542 0.04944  0.00783  0.00029  8   ARG A CG    
81   C CD    A ARG A 10  ? 0.54318 0.62139 0.42875 0.06317  0.01501  -0.00874 8   ARG A CD    
82   C CD    B ARG A 10  ? 0.54980 0.62084 0.42207 0.05943  0.00579  -0.01197 8   ARG A CD    
83   N NE    A ARG A 10  ? 0.56729 0.62019 0.45118 0.06303  0.00992  -0.02125 8   ARG A NE    
84   N NE    B ARG A 10  ? 0.55615 0.60666 0.42225 0.06401  0.00460  -0.02496 8   ARG A NE    
85   C CZ    A ARG A 10  ? 0.48135 0.52823 0.37928 0.06199  0.01245  -0.02183 8   ARG A CZ    
86   C CZ    B ARG A 10  ? 0.59056 0.61879 0.43712 0.06548  -0.00340 -0.03827 8   ARG A CZ    
87   N NH1   A ARG A 10  ? 0.48604 0.55048 0.40258 0.06005  0.01912  -0.01141 8   ARG A NH1   
88   N NH1   B ARG A 10  ? 0.64939 0.67559 0.48166 0.06266  -0.01129 -0.04127 8   ARG A NH1   
89   N NH2   A ARG A 10  ? 0.47752 0.49945 0.36963 0.06180  0.00737  -0.03262 8   ARG A NH2   
90   N NH2   B ARG A 10  ? 0.61454 0.62053 0.45448 0.06917  -0.00446 -0.04847 8   ARG A NH2   
91   N N     . THR A 11  ? 0.36786 0.50040 0.29337 0.03113  0.02148  0.05313  9   THR A N     
92   C CA    . THR A 11  ? 0.34954 0.50387 0.27702 0.02589  0.02794  0.06961  9   THR A CA    
93   C C     . THR A 11  ? 0.36754 0.51779 0.31494 0.01365  0.02728  0.07839  9   THR A C     
94   O O     . THR A 11  ? 0.33988 0.51040 0.29504 0.00961  0.03368  0.08689  9   THR A O     
95   C CB    . THR A 11  ? 0.38846 0.54667 0.30284 0.02314  0.02546  0.08082  9   THR A CB    
96   O OG1   . THR A 11  ? 0.40068 0.53569 0.31930 0.01713  0.01574  0.08248  9   THR A OG1   
97   C CG2   . THR A 11  ? 0.39711 0.56315 0.28874 0.03558  0.02659  0.07262  9   THR A CG2   
98   N N     . GLN A 12  ? 0.33981 0.46547 0.29506 0.00805  0.01928  0.07632  10  GLN A N     
99   C CA    . GLN A 12  ? 0.32997 0.44730 0.30083 -0.00224 0.01767  0.08196  10  GLN A CA    
100  C C     . GLN A 12  ? 0.31356 0.43959 0.29530 0.00038  0.02257  0.07466  10  GLN A C     
101  O O     . GLN A 12  ? 0.34073 0.47650 0.33310 -0.00784 0.02478  0.08266  10  GLN A O     
102  C CB    . GLN A 12  ? 0.34443 0.43378 0.31918 -0.00422 0.00881  0.07825  10  GLN A CB    
103  C CG    . GLN A 12  ? 0.42409 0.50283 0.38922 -0.00749 0.00312  0.08907  10  GLN A CG    
104  C CD    . GLN A 12  ? 0.44942 0.52716 0.41463 -0.02022 0.00307  0.10596  10  GLN A CD    
105  O OE1   . GLN A 12  ? 0.50728 0.57428 0.48183 -0.02833 0.00114  0.10802  10  GLN A OE1   
106  N NE2   . GLN A 12  ? 0.52626 0.61460 0.47972 -0.02314 0.00455  0.11862  10  GLN A NE2   
107  N N     . GLY A 13  ? 0.30929 0.43088 0.28766 0.01109  0.02335  0.05997  11  GLY A N     
108  C CA    . GLY A 13  ? 0.31048 0.43698 0.29700 0.01537  0.02739  0.05307  11  GLY A CA    
109  C C     . GLY A 13  ? 0.29921 0.45633 0.28601 0.01863  0.03604  0.06006  11  GLY A C     
110  O O     . GLY A 13  ? 0.31194 0.48039 0.31117 0.01635  0.03883  0.06267  11  GLY A O     
111  N N     . ALA A 14  ? 0.30026 0.47426 0.27328 0.02453  0.04041  0.06375  12  ALA A N     
112  C CA    . ALA A 14  ? 0.33480 0.54456 0.30768 0.02895  0.04979  0.07207  12  ALA A CA    
113  C C     . ALA A 14  ? 0.37134 0.59928 0.35832 0.01197  0.05046  0.09069  12  ALA A C     
114  O O     . ALA A 14  ? 0.35379 0.61049 0.35187 0.01053  0.05612  0.09766  12  ALA A O     
115  C CB    . ALA A 14  ? 0.31773 0.54043 0.26954 0.04028  0.05425  0.07117  12  ALA A CB    
116  N N     . LEU A 15  ? 0.31146 0.52283 0.29720 -0.00113 0.04403  0.09943  13  LEU A N     
117  C CA    . LEU A 15  ? 0.32081 0.54008 0.31670 -0.01994 0.04219  0.11716  13  LEU A CA    
118  C C     . LEU A 15  ? 0.32710 0.53745 0.33998 -0.02903 0.03809  0.11580  13  LEU A C     
119  O O     . LEU A 15  ? 0.34405 0.57455 0.36791 -0.04220 0.03903  0.12856  13  LEU A O     
120  C CB    . LEU A 15  ? 0.32726 0.52129 0.31403 -0.02932 0.03464  0.12489  13  LEU A CB    
121  C CG    . LEU A 15  ? 0.35120 0.55780 0.32081 -0.02417 0.03805  0.13127  13  LEU A CG    
122  C CD1   . LEU A 15  ? 0.41799 0.59332 0.37754 -0.02860 0.02898  0.13466  13  LEU A CD1   
123  C CD2   . LEU A 15  ? 0.32197 0.56699 0.29287 -0.03292 0.04572  0.15016  13  LEU A CD2   
124  N N     . LEU A 16  ? 0.28736 0.46924 0.30215 -0.02323 0.03312  0.10119  14  LEU A N     
125  C CA    . LEU A 16  ? 0.27536 0.44108 0.30236 -0.03156 0.02750  0.09893  14  LEU A CA    
126  C C     . LEU A 16  ? 0.33492 0.51199 0.37085 -0.02234 0.03138  0.08908  14  LEU A C     
127  O O     . LEU A 16  ? 0.32889 0.49331 0.37382 -0.02767 0.02686  0.08599  14  LEU A O     
128  C CB    . LEU A 16  ? 0.31424 0.44060 0.33662 -0.03136 0.01911  0.09100  14  LEU A CB    
129  C CG    . LEU A 16  ? 0.36345 0.47238 0.37603 -0.03884 0.01348  0.10047  14  LEU A CG    
130  C CD1   . LEU A 16  ? 0.34438 0.42244 0.35152 -0.03173 0.00704  0.09054  14  LEU A CD1   
131  C CD2   . LEU A 16  ? 0.37646 0.47997 0.39257 -0.05704 0.00867  0.11455  14  LEU A CD2   
132  N N     . TYR A 17  ? 0.30978 0.50870 0.34135 -0.00766 0.03923  0.08410  15  TYR A N     
133  C CA    . TYR A 17  ? 0.28956 0.49041 0.32523 0.00443  0.04182  0.07288  15  TYR A CA    
134  C C     . TYR A 17  ? 0.29140 0.50640 0.34363 -0.00417 0.04071  0.07870  15  TYR A C     
135  O O     . TYR A 17  ? 0.27264 0.51885 0.33343 -0.01297 0.04327  0.09204  15  TYR A O     
136  C CB    . TYR A 17  ? 0.33270 0.55668 0.35864 0.02243  0.05051  0.06879  15  TYR A CB    
137  C CG    . TYR A 17  ? 0.33247 0.55603 0.36046 0.03597  0.05271  0.05851  15  TYR A CG    
138  C CD1   . TYR A 17  ? 0.33453 0.52508 0.35346 0.04427  0.04913  0.04382  15  TYR A CD1   
139  C CD2   . TYR A 17  ? 0.29237 0.54926 0.33171 0.03954  0.05769  0.06472  15  TYR A CD2   
140  C CE1   . TYR A 17  ? 0.35351 0.53940 0.37201 0.05613  0.05045  0.03553  15  TYR A CE1   
141  C CE2   . TYR A 17  ? 0.33891 0.59332 0.37886 0.05336  0.05903  0.05587  15  TYR A CE2   
142  C CZ    . TYR A 17  ? 0.37781 0.59443 0.40610 0.06174  0.05543  0.04135  15  TYR A CZ    
143  O OH    . TYR A 17  ? 0.42040 0.63032 0.44673 0.07513  0.05619  0.03351  15  TYR A OH    
144  N N     . ARG A 18  ? 0.29331 0.48804 0.34977 -0.00171 0.03685  0.06906  16  ARG A N     
145  C CA    . ARG A 18  ? 0.31953 0.52452 0.38979 -0.00843 0.03457  0.07238  16  ARG A CA    
146  C C     . ARG A 18  ? 0.26938 0.48900 0.34111 0.00846  0.03985  0.06525  16  ARG A C     
147  O O     . ARG A 18  ? 0.31840 0.51563 0.38095 0.02102  0.04019  0.05292  16  ARG A O     
148  C CB    . ARG A 18  ? 0.31759 0.48818 0.38941 -0.01739 0.02597  0.06742  16  ARG A CB    
149  C CG    . ARG A 18  ? 0.33667 0.49139 0.40675 -0.03413 0.01927  0.07577  16  ARG A CG    
150  C CD    . ARG A 18  ? 0.32115 0.44066 0.38959 -0.03806 0.01139  0.06863  16  ARG A CD    
151  N NE    . ARG A 18  ? 0.31302 0.41223 0.37469 -0.02549 0.01235  0.05653  16  ARG A NE    
152  C CZ    . ARG A 18  ? 0.32717 0.40103 0.38721 -0.02458 0.00771  0.04919  16  ARG A CZ    
153  N NH1   . ARG A 18  ? 0.38040 0.44244 0.44258 -0.03333 0.00172  0.05081  16  ARG A NH1   
154  N NH2   . ARG A 18  ? 0.35170 0.41289 0.40702 -0.01500 0.00879  0.04021  16  ARG A NH2   
155  N N     . ASP A 19  ? 0.27713 0.53425 0.35996 0.00851  0.04335  0.07370  17  ASP A N     
156  C CA    . ASP A 19  ? 0.29516 0.56889 0.37863 0.02724  0.04845  0.06819  17  ASP A CA    
157  C C     . ASP A 19  ? 0.31245 0.57300 0.40366 0.02486  0.04276  0.06386  17  ASP A C     
158  O O     . ASP A 19  ? 0.36520 0.65365 0.46924 0.02251  0.04221  0.07033  17  ASP A O     
159  C CB    . ASP A 19  ? 0.31186 0.63826 0.40397 0.03146  0.05561  0.07980  17  ASP A CB    
160  C CG    . ASP A 19  ? 0.44109 0.78599 0.53130 0.05535  0.06149  0.07419  17  ASP A CG    
161  O OD1   . ASP A 19  ? 0.54640 0.86063 0.62088 0.07211  0.06224  0.06060  17  ASP A OD1   
162  O OD2   . ASP A 19  ? 0.50501 0.89597 0.60873 0.05750  0.06508  0.08409  17  ASP A OD2   
163  N N     . LEU A 20  ? 0.29586 0.51642 0.37884 0.02607  0.03863  0.05323  18  LEU A N     
164  C CA    . LEU A 20  ? 0.31952 0.52518 0.40742 0.02366  0.03339  0.04914  18  LEU A CA    
165  C C     . LEU A 20  ? 0.31845 0.53099 0.40351 0.04271  0.03710  0.04383  18  LEU A C     
166  O O     . LEU A 20  ? 0.30737 0.51515 0.38016 0.05918  0.04217  0.03782  18  LEU A O     
167  C CB    . LEU A 20  ? 0.30450 0.46881 0.38479 0.01870  0.02846  0.04086  18  LEU A CB    
168  C CG    . LEU A 20  ? 0.30159 0.45517 0.38210 0.00305  0.02421  0.04563  18  LEU A CG    
169  C CD1   . LEU A 20  ? 0.32441 0.44265 0.39741 0.00219  0.02045  0.03742  18  LEU A CD1   
170  C CD2   . LEU A 20  ? 0.39887 0.56383 0.48973 -0.01332 0.01868  0.05489  18  LEU A CD2   
171  N N     . PRO A 21  ? 0.30886 0.52917 0.40266 0.04133  0.03373  0.04554  19  PRO A N     
172  C CA    . PRO A 21  ? 0.28325 0.51478 0.37484 0.06061  0.03698  0.04290  19  PRO A CA    
173  C C     . PRO A 21  ? 0.31894 0.51370 0.39285 0.07565  0.03824  0.03134  19  PRO A C     
174  O O     . PRO A 21  ? 0.28483 0.48452 0.35030 0.09559  0.04231  0.02849  19  PRO A O     
175  C CB    . PRO A 21  ? 0.36513 0.60581 0.46852 0.05211  0.03085  0.04686  19  PRO A CB    
176  C CG    . PRO A 21  ? 0.34075 0.58422 0.45347 0.02827  0.02507  0.05332  19  PRO A CG    
177  C CD    . PRO A 21  ? 0.34270 0.55987 0.44630 0.02291  0.02600  0.04969  19  PRO A CD    
178  N N     . TRP A 22  ? 0.30022 0.45865 0.36760 0.06686  0.03444  0.02515  20  TRP A N     
179  C CA    . TRP A 22  ? 0.30979 0.43285 0.36130 0.07631  0.03422  0.01566  20  TRP A CA    
180  C C     . TRP A 22  ? 0.33094 0.43957 0.36832 0.08148  0.03674  0.00996  20  TRP A C     
181  O O     . TRP A 22  ? 0.33554 0.41194 0.35931 0.08443  0.03486  0.00227  20  TRP A O     
182  C CB    . TRP A 22  ? 0.28666 0.38335 0.33952 0.06392  0.02895  0.01296  20  TRP A CB    
183  C CG    . TRP A 22  ? 0.25764 0.35469 0.31847 0.04716  0.02607  0.01570  20  TRP A CG    
184  C CD1   . TRP A 22  ? 0.29393 0.37678 0.34998 0.04155  0.02562  0.01296  20  TRP A CD1   
185  C CD2   . TRP A 22  ? 0.28091 0.39068 0.35367 0.03440  0.02217  0.02164  20  TRP A CD2   
186  N NE1   . TRP A 22  ? 0.29194 0.37712 0.35583 0.02800  0.02220  0.01713  20  TRP A NE1   
187  C CE2   . TRP A 22  ? 0.31623 0.41559 0.38928 0.02288  0.01978  0.02214  20  TRP A CE2   
188  C CE3   . TRP A 22  ? 0.27962 0.40744 0.36137 0.03155  0.01947  0.02649  20  TRP A CE3   
189  C CZ2   . TRP A 22  ? 0.28460 0.38595 0.36417 0.00927  0.01469  0.02680  20  TRP A CZ2   
190  C CZ3   . TRP A 22  ? 0.27003 0.40173 0.35914 0.01590  0.01389  0.03095  20  TRP A CZ3   
191  C CH2   . TRP A 22  ? 0.28458 0.40049 0.37136 0.00522  0.01149  0.03078  20  TRP A CH2   
192  N N     . ARG A 23  ? 0.30510 0.43704 0.34459 0.08148  0.04035  0.01405  21  ARG A N     
193  C CA    . ARG A 23  ? 0.33106 0.45011 0.35570 0.08588  0.04204  0.00855  21  ARG A CA    
194  C C     . ARG A 23  ? 0.35527 0.47796 0.36364 0.10834  0.04703  0.00375  21  ARG A C     
195  O O     . ARG A 23  ? 0.33617 0.48686 0.34913 0.12055  0.05132  0.00816  21  ARG A O     
196  C CB    . ARG A 23  ? 0.32560 0.46467 0.35763 0.07422  0.04313  0.01572  21  ARG A CB    
197  C CG    . ARG A 23  ? 0.33118 0.45425 0.37148 0.05518  0.03718  0.01748  21  ARG A CG    
198  C CD    . ARG A 23  ? 0.34376 0.47812 0.38641 0.04502  0.03728  0.02411  21  ARG A CD    
199  N NE    . ARG A 23  ? 0.32161 0.43371 0.36644 0.03214  0.03138  0.02326  21  ARG A NE    
200  C CZ    . ARG A 23  ? 0.32842 0.44000 0.37189 0.02419  0.02979  0.02755  21  ARG A CZ    
201  N NH1   . ARG A 23  ? 0.32805 0.46078 0.36884 0.02505  0.03366  0.03417  21  ARG A NH1   
202  N NH2   . ARG A 23  ? 0.34714 0.43782 0.39122 0.01629  0.02442  0.02580  21  ARG A NH2   
203  N N     . ASN A 24  ? 0.38701 0.48075 0.37493 0.11441  0.04581  -0.00568 22  ASN A N     
204  C CA    . ASN A 24  ? 0.39484 0.48401 0.36089 0.13692  0.04955  -0.01251 22  ASN A CA    
205  C C     . ASN A 24  ? 0.38752 0.46784 0.34726 0.15349  0.04987  -0.01501 22  ASN A C     
206  O O     . ASN A 24  ? 0.44148 0.53979 0.39334 0.17495  0.05522  -0.01516 22  ASN A O     
207  C CB    . ASN A 24  ? 0.40106 0.53176 0.36957 0.14504  0.05707  -0.00642 22  ASN A CB    
208  C CG    . ASN A 24  ? 0.45935 0.59699 0.43273 0.12850  0.05629  -0.00248 22  ASN A CG    
209  O OD1   . ASN A 24  ? 0.46511 0.57529 0.42303 0.12605  0.05263  -0.01019 22  ASN A OD1   
210  N ND2   . ASN A 24  ? 0.44513 0.61745 0.43944 0.11578  0.05850  0.00997  22  ASN A ND2   
211  N N     . LEU A 25  ? 0.42030 0.47421 0.38302 0.14449  0.04431  -0.01630 23  LEU A N     
212  C CA    . LEU A 25  ? 0.43289 0.46909 0.38632 0.15841  0.04301  -0.01866 23  LEU A CA    
213  C C     . LEU A 25  ? 0.52493 0.50899 0.45033 0.16328  0.03791  -0.02945 23  LEU A C     
214  O O     . LEU A 25  ? 0.68718 0.64908 0.60791 0.14825  0.03352  -0.03357 23  LEU A O     
215  C CB    . LEU A 25  ? 0.40306 0.44189 0.37518 0.14458  0.03972  -0.01238 23  LEU A CB    
216  C CG    . LEU A 25  ? 0.40817 0.49338 0.40627 0.13726  0.04228  -0.00193 23  LEU A CG    
217  C CD1   . LEU A 25  ? 0.43122 0.51317 0.44140 0.12725  0.03807  0.00211  23  LEU A CD1   
218  C CD2   . LEU A 25  ? 0.43743 0.55928 0.43641 0.15752  0.04834  0.00189  23  LEU A CD2   
219  N N     . ASP A 26  ? 0.55296 0.51672 0.45906 0.18386  0.03763  -0.03353 24  ASP A N     
220  C CA    . ASP A 26  ? 0.70279 0.61068 0.58067 0.18560  0.03089  -0.04273 24  ASP A CA    
221  C C     . ASP A 26  ? 0.69378 0.57563 0.57422 0.17497  0.02557  -0.03946 24  ASP A C     
222  O O     . ASP A 26  ? 0.69336 0.53256 0.55803 0.16441  0.01881  -0.04414 24  ASP A O     
223  C CB    . ASP A 26  ? 0.76233 0.65125 0.60959 0.21483  0.03205  -0.05045 24  ASP A CB    
224  C CG    . ASP A 26  ? 0.89089 0.77498 0.72010 0.21891  0.03232  -0.05849 24  ASP A CG    
225  O OD1   . ASP A 26  ? 0.83706 0.72744 0.67506 0.20149  0.03158  -0.05917 24  ASP A OD1   
226  O OD2   . ASP A 26  ? 1.01086 0.88786 0.81896 0.23534  0.03179  -0.06204 24  ASP A OD2   
227  N N     . ASP A 27  ? 0.54416 0.45225 0.44401 0.17583  0.02804  -0.03093 25  ASP A N     
228  C CA    . ASP A 27  ? 0.51406 0.39974 0.41405 0.16891  0.02373  -0.02710 25  ASP A CA    
229  C C     . ASP A 27  ? 0.50407 0.38421 0.41819 0.14101  0.02034  -0.02463 25  ASP A C     
230  O O     . ASP A 27  ? 0.46529 0.37928 0.40408 0.12894  0.02271  -0.01933 25  ASP A O     
231  C CB    . ASP A 27  ? 0.50270 0.42201 0.41902 0.17842  0.02687  -0.01887 25  ASP A CB    
232  C CG    . ASP A 27  ? 0.56679 0.46608 0.48315 0.17125  0.02267  -0.01403 25  ASP A CG    
233  O OD1   . ASP A 27  ? 0.56132 0.41757 0.46145 0.16248  0.01778  -0.01667 25  ASP A OD1   
234  O OD2   . ASP A 27  ? 0.59743 0.52531 0.52962 0.17355  0.02389  -0.00694 25  ASP A OD2   
235  N N     . PRO A 28  ? 0.51873 0.35782 0.41766 0.13020  0.01450  -0.02771 26  PRO A N     
236  C CA    . PRO A 28  ? 0.47930 0.31972 0.39306 0.10514  0.01207  -0.02467 26  PRO A CA    
237  C C     . PRO A 28  ? 0.42991 0.29110 0.36366 0.09765  0.01375  -0.01631 26  PRO A C     
238  O O     . PRO A 28  ? 0.40878 0.28783 0.36061 0.08173  0.01423  -0.01350 26  PRO A O     
239  C CB    . PRO A 28  ? 0.52336 0.31615 0.41452 0.09689  0.00506  -0.02811 26  PRO A CB    
240  C CG    . PRO A 28  ? 0.63498 0.39885 0.49711 0.11677  0.00320  -0.03595 26  PRO A CG    
241  C CD    . PRO A 28  ? 0.59588 0.38574 0.46223 0.14009  0.00937  -0.03398 26  PRO A CD    
242  N N     . TYR A 29  ? 0.43576 0.29468 0.36502 0.11019  0.01429  -0.01251 27  TYR A N     
243  C CA    . TYR A 29  ? 0.40731 0.28568 0.35314 0.10347  0.01515  -0.00514 27  TYR A CA    
244  C C     . TYR A 29  ? 0.36933 0.29172 0.33852 0.10148  0.01861  -0.00284 27  TYR A C     
245  O O     . TYR A 29  ? 0.33809 0.27473 0.32239 0.08747  0.01842  0.00013  27  TYR A O     
246  C CB    . TYR A 29  ? 0.39070 0.25681 0.32480 0.11824  0.01411  -0.00120 27  TYR A CB    
247  C CG    . TYR A 29  ? 0.39989 0.29280 0.35043 0.11536  0.01493  0.00587  27  TYR A CG    
248  C CD1   . TYR A 29  ? 0.37515 0.26514 0.33217 0.09855  0.01379  0.00975  27  TYR A CD1   
249  C CD2   . TYR A 29  ? 0.39466 0.31801 0.35358 0.12972  0.01656  0.00872  27  TYR A CD2   
250  C CE1   . TYR A 29  ? 0.37202 0.28437 0.34067 0.09669  0.01394  0.01489  27  TYR A CE1   
251  C CE2   . TYR A 29  ? 0.39095 0.33775 0.36319 0.12579  0.01575  0.01449  27  TYR A CE2   
252  C CZ    . TYR A 29  ? 0.37006 0.30874 0.34548 0.10973  0.01425  0.01695  27  TYR A CZ    
253  O OH    . TYR A 29  ? 0.38455 0.34443 0.36987 0.10674  0.01285  0.02156  27  TYR A OH    
254  N N     . ALA A 30  ? 0.36772 0.31194 0.33885 0.11559  0.02154  -0.00373 28  ALA A N     
255  C CA    . ALA A 30  ? 0.34148 0.32696 0.33401 0.11097  0.02399  -0.00016 28  ALA A CA    
256  C C     . ALA A 30  ? 0.34489 0.33388 0.34654 0.09389  0.02385  -0.00188 28  ALA A C     
257  O O     . ALA A 30  ? 0.31685 0.32570 0.33462 0.08225  0.02333  0.00168  28  ALA A O     
258  C CB    . ALA A 30  ? 0.35830 0.36874 0.35040 0.12853  0.02783  0.00014  28  ALA A CB    
259  N N     . VAL A 31  ? 0.35097 0.31873 0.34067 0.09245  0.02337  -0.00750 29  VAL A N     
260  C CA    . VAL A 31  ? 0.33461 0.30499 0.33196 0.07733  0.02254  -0.00877 29  VAL A CA    
261  C C     . VAL A 31  ? 0.29879 0.26109 0.30346 0.06263  0.01994  -0.00673 29  VAL A C     
262  O O     . VAL A 31  ? 0.32054 0.29763 0.33847 0.05248  0.01976  -0.00468 29  VAL A O     
263  C CB    . VAL A 31  ? 0.35388 0.30346 0.33513 0.07930  0.02140  -0.01542 29  VAL A CB    
264  C CG1   . VAL A 31  ? 0.38112 0.33126 0.36966 0.06337  0.01931  -0.01617 29  VAL A CG1   
265  C CG2   . VAL A 31  ? 0.35638 0.32148 0.33167 0.09434  0.02522  -0.01724 29  VAL A CG2   
266  N N     . LEU A 32  ? 0.32234 0.26043 0.31689 0.06189  0.01790  -0.00685 30  LEU A N     
267  C CA    . LEU A 32  ? 0.30540 0.24024 0.30649 0.04925  0.01657  -0.00390 30  LEU A CA    
268  C C     . LEU A 32  ? 0.30849 0.26609 0.32344 0.04786  0.01760  0.00017  30  LEU A C     
269  O O     . LEU A 32  ? 0.27391 0.23984 0.29821 0.03837  0.01729  0.00097  30  LEU A O     
270  C CB    . LEU A 32  ? 0.32717 0.23470 0.31427 0.04915  0.01457  -0.00238 30  LEU A CB    
271  C CG    . LEU A 32  ? 0.33594 0.24507 0.32949 0.03752  0.01443  0.00238  30  LEU A CG    
272  C CD1   . LEU A 32  ? 0.33904 0.25429 0.34084 0.02440  0.01389  0.00122  30  LEU A CD1   
273  C CD2   . LEU A 32  ? 0.36976 0.25251 0.34844 0.03689  0.01257  0.00608  30  LEU A CD2   
274  N N     . VAL A 33  ? 0.31341 0.28123 0.32863 0.05792  0.01817  0.00254  31  VAL A N     
275  C CA    . VAL A 33  ? 0.29168 0.27973 0.31831 0.05482  0.01738  0.00597  31  VAL A CA    
276  C C     . VAL A 33  ? 0.26683 0.27215 0.30529 0.04677  0.01706  0.00548  31  VAL A C     
277  O O     . VAL A 33  ? 0.26305 0.27197 0.30729 0.03851  0.01534  0.00595  31  VAL A O     
278  C CB    . VAL A 33  ? 0.31318 0.31455 0.33962 0.06659  0.01710  0.00920  31  VAL A CB    
279  C CG1   . VAL A 33  ? 0.30686 0.32982 0.34465 0.06083  0.01451  0.01232  31  VAL A CG1   
280  C CG2   . VAL A 33  ? 0.33273 0.31277 0.34519 0.07489  0.01661  0.01066  31  VAL A CG2   
281  N N     . SER A 34  ? 0.27001 0.28442 0.30997 0.04978  0.01859  0.00464  32  SER A N     
282  C CA    . SER A 34  ? 0.25185 0.28056 0.30138 0.04133  0.01790  0.00576  32  SER A CA    
283  C C     . SER A 34  ? 0.28583 0.30144 0.33534 0.03221  0.01677  0.00324  32  SER A C     
284  O O     . SER A 34  ? 0.24732 0.26725 0.30269 0.02495  0.01460  0.00431  32  SER A O     
285  C CB    . SER A 34  ? 0.25021 0.29278 0.29996 0.04662  0.02053  0.00649  32  SER A CB    
286  O OG    . SER A 34  ? 0.28799 0.31518 0.32815 0.04904  0.02192  0.00195  32  SER A OG    
287  N N     . GLU A 35  ? 0.26869 0.26805 0.31070 0.03271  0.01751  0.00003  33  GLU A N     
288  C CA    . GLU A 35  ? 0.29402 0.28699 0.33772 0.02477  0.01638  -0.00153 33  GLU A CA    
289  C C     . GLU A 35  ? 0.28673 0.27837 0.33369 0.02064  0.01563  -0.00040 33  GLU A C     
290  O O     . GLU A 35  ? 0.27523 0.27026 0.32670 0.01642  0.01461  -0.00062 33  GLU A O     
291  C CB    . GLU A 35  ? 0.32725 0.30500 0.36212 0.02441  0.01609  -0.00456 33  GLU A CB    
292  C CG    . GLU A 35  ? 0.38414 0.36149 0.42116 0.01718  0.01437  -0.00610 33  GLU A CG    
293  C CD    . GLU A 35  ? 0.36519 0.35457 0.40663 0.01708  0.01415  -0.00575 33  GLU A CD    
294  O OE1   . GLU A 35  ? 0.37911 0.37311 0.42613 0.01241  0.01265  -0.00494 33  GLU A OE1   
295  O OE2   . GLU A 35  ? 0.39365 0.38936 0.43289 0.02241  0.01570  -0.00527 33  GLU A OE2   
296  N N     . VAL A 36  ? 0.28337 0.26972 0.32631 0.02328  0.01619  0.00093  34  VAL A N     
297  C CA    . VAL A 36  ? 0.26042 0.24776 0.30463 0.02064  0.01610  0.00216  34  VAL A CA    
298  C C     . VAL A 36  ? 0.23191 0.22883 0.28045 0.02033  0.01393  0.00201  34  VAL A C     
299  O O     . VAL A 36  ? 0.25207 0.24941 0.30140 0.01815  0.01304  0.00084  34  VAL A O     
300  C CB    . VAL A 36  ? 0.28364 0.26315 0.32081 0.02359  0.01698  0.00475  34  VAL A CB    
301  C CG1   . VAL A 36  ? 0.28670 0.27068 0.32378 0.02226  0.01732  0.00623  34  VAL A CG1   
302  C CG2   . VAL A 36  ? 0.29174 0.25643 0.32230 0.02067  0.01765  0.00541  34  VAL A CG2   
303  N N     . MET A 37  ? 0.24745 0.25224 0.29786 0.02266  0.01252  0.00333  35  MET A N     
304  C CA    . MET A 37  ? 0.21141 0.22432 0.26518 0.01931  0.00873  0.00399  35  MET A CA    
305  C C     . MET A 37  ? 0.25231 0.26337 0.30856 0.01385  0.00693  0.00299  35  MET A C     
306  O O     . MET A 37  ? 0.25355 0.26088 0.30794 0.01028  0.00297  0.00208  35  MET A O     
307  C CB    . MET A 37  ? 0.25156 0.27900 0.30919 0.02175  0.00786  0.00722  35  MET A CB    
308  C CG    . MET A 37  ? 0.23982 0.27182 0.29505 0.02638  0.00654  0.00890  35  MET A CG    
309  S SD    . MET A 37  ? 0.26240 0.32001 0.32536 0.02901  0.00469  0.01375  35  MET A SD    
310  C CE    . MET A 37  ? 0.26230 0.32242 0.32033 0.03618  0.00255  0.01548  35  MET A CE    
311  N N     . LEU A 38  ? 0.26220 0.27319 0.32018 0.01377  0.00910  0.00297  36  LEU A N     
312  C CA    . LEU A 38  ? 0.24441 0.25349 0.30370 0.00964  0.00734  0.00314  36  LEU A CA    
313  C C     . LEU A 38  ? 0.25097 0.25095 0.30782 0.01025  0.00695  0.00043  36  LEU A C     
314  O O     . LEU A 38  ? 0.28242 0.27818 0.33836 0.00857  0.00440  0.00064  36  LEU A O     
315  C CB    . LEU A 38  ? 0.22211 0.23588 0.28246 0.01047  0.00970  0.00408  36  LEU A CB    
316  C CG    . LEU A 38  ? 0.25998 0.28813 0.32336 0.01044  0.01020  0.00799  36  LEU A CG    
317  C CD1   . LEU A 38  ? 0.27620 0.30856 0.33677 0.01570  0.01394  0.00735  36  LEU A CD1   
318  C CD2   . LEU A 38  ? 0.28056 0.31382 0.34706 0.00223  0.00634  0.01253  36  LEU A CD2   
319  N N     . GLN A 39  ? 0.23942 0.23754 0.29481 0.01307  0.00941  -0.00119 37  GLN A N     
320  C CA    . GLN A 39  ? 0.23831 0.23483 0.29303 0.01490  0.00995  -0.00277 37  GLN A CA    
321  C C     . GLN A 39  ? 0.27293 0.26292 0.32253 0.01706  0.00645  -0.00459 37  GLN A C     
322  O O     . GLN A 39  ? 0.27761 0.26454 0.32239 0.01798  0.00504  -0.00576 37  GLN A O     
323  C CB    . GLN A 39  ? 0.25014 0.24954 0.30437 0.01602  0.01348  -0.00233 37  GLN A CB    
324  C CG    . GLN A 39  ? 0.26711 0.26583 0.32243 0.01285  0.01534  -0.00083 37  GLN A CG    
325  C CD    . GLN A 39  ? 0.28700 0.28536 0.33999 0.01156  0.01793  0.00149  37  GLN A CD    
326  O OE1   . GLN A 39  ? 0.29730 0.30026 0.34900 0.01376  0.01943  0.00224  37  GLN A OE1   
327  N NE2   . GLN A 39  ? 0.30451 0.29578 0.35480 0.00801  0.01818  0.00285  37  GLN A NE2   
328  N N     . GLN A 40  ? 0.25179 0.23731 0.30017 0.01843  0.00422  -0.00506 38  GLN A N     
329  C CA    . GLN A 40  ? 0.23808 0.21047 0.27749 0.02165  -0.00034 -0.00739 38  GLN A CA    
330  C C     . GLN A 40  ? 0.25576 0.21950 0.29030 0.01555  -0.00550 -0.00710 38  GLN A C     
331  O O     . GLN A 40  ? 0.26876 0.21991 0.29291 0.01748  -0.00975 -0.01044 38  GLN A O     
332  C CB    . GLN A 40  ? 0.26283 0.23596 0.29686 0.03074  0.00185  -0.01090 38  GLN A CB    
333  C CG    . GLN A 40  ? 0.30781 0.29439 0.34822 0.03588  0.00607  -0.00987 38  GLN A CG    
334  C CD    . GLN A 40  ? 0.31149 0.29141 0.34867 0.04146  0.00282  -0.01022 38  GLN A CD    
335  O OE1   . GLN A 40  ? 0.32652 0.30036 0.35505 0.05203  0.00174  -0.01320 38  GLN A OE1   
336  N NE2   . GLN A 40  ? 0.34263 0.32246 0.38464 0.03579  0.00105  -0.00715 38  GLN A NE2   
337  N N     . THR A 41  ? 0.26262 0.23393 0.30378 0.00812  -0.00577 -0.00300 39  THR A N     
338  C CA    . THR A 41  ? 0.23154 0.20255 0.27159 0.00055  -0.01067 -0.00093 39  THR A CA    
339  C C     . THR A 41  ? 0.26662 0.24567 0.31291 -0.00713 -0.01146 0.00512  39  THR A C     
340  O O     . THR A 41  ? 0.27398 0.26619 0.32731 -0.00523 -0.00622 0.00710  39  THR A O     
341  C CB    . THR A 41  ? 0.27205 0.25495 0.31548 0.00175  -0.00839 -0.00106 39  THR A CB    
342  O OG1   . THR A 41  ? 0.25741 0.23591 0.29516 0.00909  -0.00603 -0.00530 39  THR A OG1   
343  C CG2   . THR A 41  ? 0.29464 0.28018 0.33694 -0.00599 -0.01489 0.00095  39  THR A CG2   
344  N N     . GLN A 42  ? 0.26946 0.24051 0.31169 -0.01623 -0.01829 0.00829  40  GLN A N     
345  C CA    . GLN A 42  ? 0.27043 0.25071 0.31784 -0.02502 -0.01909 0.01592  40  GLN A CA    
346  C C     . GLN A 42  ? 0.31760 0.32587 0.37652 -0.02706 -0.01502 0.02044  40  GLN A C     
347  O O     . GLN A 42  ? 0.27287 0.29094 0.33481 -0.02676 -0.01568 0.01957  40  GLN A O     
348  C CB    . GLN A 42  ? 0.32833 0.29246 0.36776 -0.03718 -0.02856 0.01964  40  GLN A CB    
349  C CG    . GLN A 42  ? 0.31707 0.25251 0.34349 -0.03508 -0.03286 0.01816  40  GLN A CG    
350  C CD    . GLN A 42  ? 0.41988 0.33340 0.43503 -0.04867 -0.04383 0.02199  40  GLN A CD    
351  O OE1   . GLN A 42  ? 0.49928 0.42639 0.52056 -0.06314 -0.04732 0.02899  40  GLN A OE1   
352  N NE2   . GLN A 42  ? 0.43589 0.31585 0.43396 -0.04441 -0.04979 0.01816  40  GLN A NE2   
353  N N     A VAL A 43  ? 0.28756 0.30952 0.35159 -0.02802 -0.01104 0.02565  41  VAL A N     
354  N N     B VAL A 43  ? 0.28706 0.30894 0.35107 -0.02778 -0.01093 0.02553  41  VAL A N     
355  C CA    A VAL A 43  ? 0.28012 0.33045 0.35341 -0.02691 -0.00633 0.03013  41  VAL A CA    
356  C CA    B VAL A 43  ? 0.27935 0.32966 0.35260 -0.02692 -0.00629 0.03019  41  VAL A CA    
357  C C     A VAL A 43  ? 0.26017 0.32637 0.33930 -0.03635 -0.01112 0.03551  41  VAL A C     
358  C C     B VAL A 43  ? 0.25995 0.32630 0.33911 -0.03635 -0.01104 0.03560  41  VAL A C     
359  O O     A VAL A 43  ? 0.26073 0.34767 0.34648 -0.03109 -0.00836 0.03604  41  VAL A O     
360  O O     B VAL A 43  ? 0.25999 0.34729 0.34583 -0.03105 -0.00819 0.03618  41  VAL A O     
361  C CB    A VAL A 43  ? 0.25130 0.31331 0.32616 -0.02786 -0.00244 0.03581  41  VAL A CB    
362  C CB    B VAL A 43  ? 0.25043 0.31175 0.32503 -0.02805 -0.00254 0.03587  41  VAL A CB    
363  C CG1   A VAL A 43  ? 0.28707 0.33766 0.35662 -0.01811 0.00176  0.03001  41  VAL A CG1   
364  C CG1   B VAL A 43  ? 0.29369 0.38792 0.37724 -0.03020 0.00062  0.04353  41  VAL A CG1   
365  C CG2   A VAL A 43  ? 0.28310 0.33857 0.35541 -0.04184 -0.00842 0.04365  41  VAL A CG2   
366  C CG2   B VAL A 43  ? 0.27305 0.32885 0.34388 -0.01642 0.00314  0.02993  41  VAL A CG2   
367  N N     . VAL A 44  ? 0.25484 0.31139 0.33081 -0.05065 -0.01918 0.04006  42  VAL A N     
368  C CA    . VAL A 44  ? 0.26016 0.33453 0.34243 -0.06325 -0.02532 0.04646  42  VAL A CA    
369  C C     . VAL A 44  ? 0.28185 0.35438 0.36289 -0.05874 -0.02832 0.04011  42  VAL A C     
370  O O     . VAL A 44  ? 0.29877 0.39782 0.38884 -0.06183 -0.02993 0.04432  42  VAL A O     
371  C CB    . VAL A 44  ? 0.30850 0.36556 0.38407 -0.08195 -0.03538 0.05242  42  VAL A CB    
372  C CG1   . VAL A 44  ? 0.42521 0.49614 0.50537 -0.09706 -0.04429 0.05739  42  VAL A CG1   
373  C CG2   . VAL A 44  ? 0.40168 0.47007 0.48070 -0.08861 -0.03227 0.06242  42  VAL A CG2   
374  N N     . ARG A 45  ? 0.27471 0.31848 0.34434 -0.05137 -0.02943 0.03073  43  ARG A N     
375  C CA    . ARG A 45  ? 0.29042 0.33338 0.35731 -0.04547 -0.03105 0.02505  43  ARG A CA    
376  C C     . ARG A 45  ? 0.25673 0.32085 0.33172 -0.03214 -0.02240 0.02474  43  ARG A C     
377  O O     . ARG A 45  ? 0.27133 0.35248 0.35055 -0.03019 -0.02379 0.02606  43  ARG A O     
378  C CB    . ARG A 45  ? 0.30500 0.31586 0.35714 -0.03902 -0.03276 0.01579  43  ARG A CB    
379  C CG    . ARG A 45  ? 0.35204 0.33474 0.39071 -0.04871 -0.04251 0.01416  43  ARG A CG    
380  C CD    . ARG A 45  ? 0.36097 0.31670 0.38564 -0.03676 -0.04121 0.00504  43  ARG A CD    
381  N NE    . ARG A 45  ? 0.35507 0.31016 0.37400 -0.02824 -0.04041 -0.00136 43  ARG A NE    
382  C CZ    . ARG A 45  ? 0.34781 0.28329 0.35349 -0.01793 -0.03966 -0.00884 43  ARG A CZ    
383  N NH1   . ARG A 45  ? 0.35031 0.26956 0.35028 -0.01245 -0.03815 -0.01080 43  ARG A NH1   
384  N NH2   . ARG A 45  ? 0.34299 0.27814 0.34111 -0.01157 -0.03981 -0.01384 43  ARG A NH2   
385  N N     . VAL A 46  ? 0.24083 0.30204 0.31625 -0.02259 -0.01438 0.02289  44  VAL A N     
386  C CA    . VAL A 46  ? 0.22750 0.30059 0.30610 -0.00970 -0.00731 0.02176  44  VAL A CA    
387  C C     . VAL A 46  ? 0.28781 0.39320 0.37664 -0.00895 -0.00608 0.02869  44  VAL A C     
388  O O     . VAL A 46  ? 0.26073 0.37814 0.35126 0.00060  -0.00416 0.02873  44  VAL A O     
389  C CB    . VAL A 46  ? 0.24936 0.31138 0.32468 -0.00220 -0.00077 0.01845  44  VAL A CB    
390  C CG1   . VAL A 46  ? 0.25442 0.32395 0.32964 0.01032  0.00524  0.01738  44  VAL A CG1   
391  C CG2   . VAL A 46  ? 0.25967 0.29663 0.32696 -0.00139 -0.00162 0.01241  44  VAL A CG2   
392  N N     . GLY A 47  ? 0.26542 0.38695 0.36087 -0.01862 -0.00728 0.03562  45  GLY A N     
393  C CA    . GLY A 47  ? 0.23143 0.39084 0.33839 -0.01839 -0.00576 0.04374  45  GLY A CA    
394  C C     . GLY A 47  ? 0.29561 0.47258 0.40828 -0.02224 -0.01206 0.04653  45  GLY A C     
395  O O     . GLY A 47  ? 0.30974 0.52014 0.43173 -0.01547 -0.00971 0.05177  45  GLY A O     
396  N N     . LYS A 48  ? 0.23941 0.39526 0.34551 -0.03191 -0.02043 0.04294  46  LYS A N     
397  C CA    . LYS A 48  ? 0.25696 0.42666 0.36588 -0.03632 -0.02796 0.04456  46  LYS A CA    
398  C C     . LYS A 48  ? 0.24241 0.40771 0.34622 -0.01982 -0.02501 0.03915  46  LYS A C     
399  O O     . LYS A 48  ? 0.25186 0.43577 0.35924 -0.01969 -0.03006 0.04166  46  LYS A O     
400  C CB    . LYS A 48  ? 0.29769 0.44311 0.39750 -0.05330 -0.03933 0.04207  46  LYS A CB    
401  C CG    . LYS A 48  ? 0.31269 0.46045 0.41588 -0.07265 -0.04471 0.04941  46  LYS A CG    
402  C CD    . LYS A 48  ? 0.33727 0.45665 0.42790 -0.08996 -0.05812 0.04689  46  LYS A CD    
403  C CE    . LYS A 48  ? 0.39059 0.50673 0.48236 -0.10903 -0.06291 0.05537  46  LYS A CE    
404  N NZ    . LYS A 48  ? 0.42819 0.50905 0.50381 -0.12669 -0.07714 0.05317  46  LYS A NZ    
405  N N     . TYR A 49  ? 0.24347 0.38597 0.33896 -0.00705 -0.01767 0.03291  47  TYR A N     
406  C CA    . TYR A 49  ? 0.26474 0.39750 0.35288 0.00662  -0.01509 0.02883  47  TYR A CA    
407  C C     . TYR A 49  ? 0.25297 0.39085 0.34117 0.02320  -0.00662 0.02930  47  TYR A C     
408  O O     . TYR A 49  ? 0.25740 0.39749 0.34192 0.03478  -0.00578 0.02956  47  TYR A O     
409  C CB    . TYR A 49  ? 0.26061 0.35864 0.33592 0.00645  -0.01475 0.02133  47  TYR A CB    
410  C CG    . TYR A 49  ? 0.28245 0.36992 0.35108 -0.00379 -0.02349 0.01861  47  TYR A CG    
411  C CD1   . TYR A 49  ? 0.27789 0.35819 0.34606 -0.01758 -0.02944 0.01866  47  TYR A CD1   
412  C CD2   . TYR A 49  ? 0.27568 0.35756 0.33564 0.00074  -0.02631 0.01593  47  TYR A CD2   
413  C CE1   . TYR A 49  ? 0.31192 0.37711 0.36989 -0.02629 -0.03869 0.01501  47  TYR A CE1   
414  C CE2   . TYR A 49  ? 0.27967 0.35000 0.33011 -0.00741 -0.03481 0.01216  47  TYR A CE2   
415  C CZ    . TYR A 49  ? 0.33524 0.39568 0.38393 -0.02064 -0.04130 0.01106  47  TYR A CZ    
416  O OH    . TYR A 49  ? 0.35225 0.39558 0.38735 -0.02799 -0.05096 0.00610  47  TYR A OH    
417  N N     . TRP A 50  ? 0.22439 0.36053 0.31377 0.02527  -0.00094 0.02904  48  TRP A N     
418  C CA    . TRP A 50  ? 0.23282 0.36240 0.31612 0.04121  0.00609  0.02687  48  TRP A CA    
419  C C     . TRP A 50  ? 0.25237 0.40862 0.33941 0.05535  0.00784  0.03137  48  TRP A C     
420  O O     . TRP A 50  ? 0.28110 0.42571 0.35898 0.06952  0.00972  0.02953  48  TRP A O     
421  C CB    . TRP A 50  ? 0.27207 0.39664 0.35461 0.03999  0.01064  0.02542  48  TRP A CB    
422  C CG    . TRP A 50  ? 0.25403 0.36780 0.32703 0.05518  0.01642  0.02192  48  TRP A CG    
423  C CD1   . TRP A 50  ? 0.27427 0.35696 0.33511 0.05943  0.01763  0.01629  48  TRP A CD1   
424  C CD2   . TRP A 50  ? 0.26544 0.39762 0.33809 0.06768  0.02124  0.02365  48  TRP A CD2   
425  N NE1   . TRP A 50  ? 0.26891 0.34473 0.32003 0.07291  0.02164  0.01374  48  TRP A NE1   
426  C CE2   . TRP A 50  ? 0.26973 0.37521 0.32694 0.07993  0.02431  0.01750  48  TRP A CE2   
427  C CE3   . TRP A 50  ? 0.26307 0.43301 0.34620 0.06983  0.02320  0.03022  48  TRP A CE3   
428  C CZ2   . TRP A 50  ? 0.28674 0.39778 0.33581 0.09616  0.02898  0.01601  48  TRP A CZ2   
429  C CZ3   . TRP A 50  ? 0.33660 0.51791 0.41393 0.08696  0.02926  0.02971  48  TRP A CZ3   
430  C CH2   . TRP A 50  ? 0.28835 0.43809 0.34734 0.10100  0.03195  0.02181  48  TRP A CH2   
431  N N     . ASN A 51  ? 0.25205 0.44513 0.35201 0.05234  0.00726  0.03815  49  ASN A N     
432  C CA    . ASN A 51  ? 0.27637 0.50133 0.38127 0.06812  0.00938  0.04315  49  ASN A CA    
433  C C     . ASN A 51  ? 0.27143 0.49816 0.37472 0.07324  0.00425  0.04418  49  ASN A C     
434  O O     . ASN A 51  ? 0.25102 0.47912 0.34788 0.09273  0.00676  0.04437  49  ASN A O     
435  C CB    . ASN A 51  ? 0.27185 0.54301 0.39380 0.06049  0.00902  0.05221  49  ASN A CB    
436  C CG    . ASN A 51  ? 0.28541 0.56501 0.40691 0.06579  0.01682  0.05290  49  ASN A CG    
437  O OD1   . ASN A 51  ? 0.33486 0.61005 0.45895 0.05048  0.01656  0.05408  49  ASN A OD1   
438  N ND2   . ASN A 51  ? 0.33345 0.62320 0.44916 0.08893  0.02354  0.05194  49  ASN A ND2   
439  N N     . ARG A 52  ? 0.27318 0.49731 0.37966 0.05685  -0.00348 0.04460  50  ARG A N     
440  C CA    . ARG A 52  ? 0.25517 0.48157 0.35867 0.06064  -0.00914 0.04555  50  ARG A CA    
441  C C     . ARG A 52  ? 0.26047 0.45019 0.34680 0.07337  -0.00592 0.04024  50  ARG A C     
442  O O     . ARG A 52  ? 0.28344 0.47688 0.36451 0.08817  -0.00636 0.04254  50  ARG A O     
443  C CB    . ARG A 52  ? 0.32338 0.54777 0.42925 0.03990  -0.01855 0.04516  50  ARG A CB    
444  C CG    . ARG A 52  ? 0.32093 0.54925 0.42241 0.04199  -0.02571 0.04588  50  ARG A CG    
445  C CD    . ARG A 52  ? 0.40604 0.62858 0.50621 0.02157  -0.03579 0.04392  50  ARG A CD    
446  N NE    . ARG A 52  ? 0.40421 0.58481 0.48931 0.01813  -0.03453 0.03567  50  ARG A NE    
447  C CZ    . ARG A 52  ? 0.45040 0.61439 0.52634 0.00654  -0.04225 0.03116  50  ARG A CZ    
448  N NH1   . ARG A 52  ? 0.42216 0.60330 0.50126 -0.00593 -0.05332 0.03346  50  ARG A NH1   
449  N NH2   . ARG A 52  ? 0.36751 0.49761 0.42989 0.00773  -0.03920 0.02412  50  ARG A NH2   
450  N N     . PHE A 53  ? 0.26233 0.41746 0.33971 0.06738  -0.00304 0.03415  51  PHE A N     
451  C CA    . PHE A 53  ? 0.28294 0.40426 0.34480 0.07555  -0.00022 0.03053  51  PHE A CA    
452  C C     . PHE A 53  ? 0.31962 0.43513 0.37367 0.09465  0.00488  0.03109  51  PHE A C     
453  O O     . PHE A 53  ? 0.33601 0.43757 0.37859 0.10645  0.00461  0.03240  51  PHE A O     
454  C CB    . PHE A 53  ? 0.24131 0.33470 0.29834 0.06442  0.00188  0.02499  51  PHE A CB    
455  C CG    . PHE A 53  ? 0.26654 0.32921 0.30967 0.06756  0.00395  0.02280  51  PHE A CG    
456  C CD1   . PHE A 53  ? 0.31421 0.35705 0.34749 0.07714  0.00819  0.02197  51  PHE A CD1   
457  C CD2   . PHE A 53  ? 0.28501 0.33800 0.32367 0.05992  0.00146  0.02169  51  PHE A CD2   
458  C CE1   . PHE A 53  ? 0.30198 0.31708 0.32286 0.07651  0.00941  0.02164  51  PHE A CE1   
459  C CE2   . PHE A 53  ? 0.29998 0.32926 0.32701 0.06126  0.00413  0.02146  51  PHE A CE2   
460  C CZ    . PHE A 53  ? 0.28059 0.29149 0.29972 0.06813  0.00790  0.02214  51  PHE A CZ    
461  N N     . MET A 54  ? 0.27797 0.40241 0.33580 0.09867  0.00922  0.03020  52  MET A N     
462  C CA    . MET A 54  ? 0.31163 0.42925 0.35896 0.11890  0.01372  0.02935  52  MET A CA    
463  C C     . MET A 54  ? 0.36025 0.50192 0.40856 0.13658  0.01228  0.03486  52  MET A C     
464  O O     . MET A 54  ? 0.36303 0.48603 0.39582 0.15558  0.01375  0.03422  52  MET A O     
465  C CB    . MET A 54  ? 0.29698 0.42803 0.34904 0.11999  0.01842  0.02780  52  MET A CB    
466  C CG    . MET A 54  ? 0.38289 0.48394 0.42777 0.11009  0.02056  0.02149  52  MET A CG    
467  S SD    . MET A 54  ? 0.35086 0.40021 0.37564 0.11029  0.01975  0.01608  52  MET A SD    
468  C CE    . MET A 54  ? 0.37008 0.40426 0.37547 0.13567  0.02249  0.01359  52  MET A CE    
469  N N     . GLY A 55  ? 0.31025 0.49324 0.37584 0.13075  0.00866  0.04069  53  GLY A N     
470  C CA    . GLY A 55  ? 0.31732 0.52994 0.38630 0.14733  0.00657  0.04688  53  GLY A CA    
471  C C     . GLY A 55  ? 0.34752 0.53740 0.40383 0.15286  0.00226  0.04764  53  GLY A C     
472  O O     . GLY A 55  ? 0.37835 0.56769 0.42517 0.17441  0.00247  0.05041  53  GLY A O     
473  N N     . MET A 56  ? 0.32593 0.49586 0.38002 0.13495  -0.00150 0.04545  54  MET A N     
474  C CA    . MET A 56  ? 0.32921 0.48073 0.37082 0.13921  -0.00525 0.04725  54  MET A CA    
475  C C     . MET A 56  ? 0.34820 0.45237 0.36854 0.14756  -0.00132 0.04452  54  MET A C     
476  O O     . MET A 56  ? 0.39923 0.48872 0.40572 0.16059  -0.00292 0.04818  54  MET A O     
477  C CB    . MET A 56  ? 0.35692 0.50831 0.40248 0.11857  -0.01070 0.04601  54  MET A CB    
478  C CG    . MET A 56  ? 0.49325 0.61728 0.52254 0.11972  -0.01251 0.04653  54  MET A CG    
479  S SD    . MET A 56  ? 0.70814 0.85238 0.74242 0.10486  -0.02174 0.04711  54  MET A SD    
480  C CE    . MET A 56  ? 0.38858 0.58342 0.43898 0.11411  -0.02691 0.05389  54  MET A CE    
481  N N     . PHE A 57  ? 0.34633 0.42613 0.36307 0.13969  0.00305  0.03892  55  PHE A N     
482  C CA    . PHE A 57  ? 0.39283 0.42738 0.39002 0.14277  0.00556  0.03652  55  PHE A CA    
483  C C     . PHE A 57  ? 0.38450 0.40871 0.37710 0.15057  0.00982  0.03172  55  PHE A C     
484  O O     . PHE A 57  ? 0.37668 0.38898 0.37116 0.13780  0.01198  0.02687  55  PHE A O     
485  C CB    . PHE A 57  ? 0.33347 0.34803 0.32948 0.12283  0.00560  0.03433  55  PHE A CB    
486  C CG    . PHE A 57  ? 0.34858 0.37800 0.34988 0.11377  0.00167  0.03712  55  PHE A CG    
487  C CD1   . PHE A 57  ? 0.40334 0.42957 0.39457 0.12224  -0.00134 0.04270  55  PHE A CD1   
488  C CD2   . PHE A 57  ? 0.33320 0.37730 0.34682 0.09785  0.00040  0.03391  55  PHE A CD2   
489  C CE1   . PHE A 57  ? 0.41379 0.45313 0.40722 0.11438  -0.00542 0.04444  55  PHE A CE1   
490  C CE2   . PHE A 57  ? 0.36706 0.42053 0.38150 0.09046  -0.00396 0.03488  55  PHE A CE2   
491  C CZ    . PHE A 57  ? 0.37436 0.42656 0.37872 0.09860  -0.00683 0.03988  55  PHE A CZ    
492  N N     . PRO A 58  ? 0.41480 0.44432 0.40018 0.17293  0.01094  0.03272  56  PRO A N     
493  C CA    . PRO A 58  ? 0.40724 0.43374 0.38818 0.18228  0.01520  0.02741  56  PRO A CA    
494  C C     . PRO A 58  ? 0.43492 0.40973 0.39324 0.18202  0.01569  0.02152  56  PRO A C     
495  O O     . PRO A 58  ? 0.46777 0.43738 0.42149 0.18564  0.01852  0.01572  56  PRO A O     
496  C CB    . PRO A 58  ? 0.43626 0.48583 0.41434 0.20952  0.01614  0.03060  56  PRO A CB    
497  C CG    . PRO A 58  ? 0.39814 0.44120 0.36932 0.21712  0.01162  0.03669  56  PRO A CG    
498  C CD    . PRO A 58  ? 0.37672 0.42494 0.36040 0.19184  0.00840  0.03890  56  PRO A CD    
499  N N     . THR A 59  ? 0.44566 0.38333 0.38907 0.17704  0.01259  0.02334  57  THR A N     
500  C CA    . THR A 59  ? 0.44264 0.32972 0.36317 0.17480  0.01137  0.01923  57  THR A CA    
501  C C     . THR A 59  ? 0.44144 0.30807 0.36132 0.15288  0.00927  0.02255  57  THR A C     
502  O O     . THR A 59  ? 0.43023 0.31483 0.36068 0.14581  0.00865  0.02812  57  THR A O     
503  C CB    . THR A 59  ? 0.48084 0.33348 0.37375 0.19840  0.00897  0.01982  57  THR A CB    
504  O OG1   . THR A 59  ? 0.49520 0.34600 0.38468 0.20267  0.00615  0.02819  57  THR A OG1   
505  C CG2   . THR A 59  ? 0.51347 0.38926 0.40496 0.22164  0.01172  0.01612  57  THR A CG2   
506  N N     . ILE A 60  ? 0.50883 0.33866 0.41502 0.14251  0.00793  0.01914  58  ILE A N     
507  C CA    . ILE A 60  ? 0.47228 0.27853 0.37324 0.12375  0.00588  0.02383  58  ILE A CA    
508  C C     . ILE A 60  ? 0.50735 0.30183 0.39715 0.13071  0.00371  0.03263  58  ILE A C     
509  O O     . ILE A 60  ? 0.49692 0.30267 0.39469 0.11855  0.00423  0.03866  58  ILE A O     
510  C CB    . ILE A 60  ? 0.48589 0.24922 0.36802 0.11532  0.00281  0.01990  58  ILE A CB    
511  C CG1   . ILE A 60  ? 0.46282 0.24193 0.35899 0.10254  0.00460  0.01288  58  ILE A CG1   
512  C CG2   . ILE A 60  ? 0.50168 0.23485 0.37210 0.09942  -0.00033 0.02776  58  ILE A CG2   
513  C CD1   . ILE A 60  ? 0.49092 0.28760 0.40508 0.07970  0.00599  0.01630  58  ILE A CD1   
514  N N     . ASP A 61  ? 0.53416 0.30422 0.40298 0.15167  0.00115  0.03355  59  ASP A N     
515  C CA    . ASP A 61  ? 0.55670 0.31107 0.41146 0.15989  -0.00166 0.04276  59  ASP A CA    
516  C C     . ASP A 61  ? 0.50980 0.31027 0.38403 0.16412  -0.00017 0.04742  59  ASP A C     
517  O O     . ASP A 61  ? 0.52010 0.31906 0.39114 0.15918  -0.00154 0.05555  59  ASP A O     
518  C CB    . ASP A 61  ? 0.63980 0.35953 0.46721 0.18553  -0.00504 0.04198  59  ASP A CB    
519  C CG    . ASP A 61  ? 0.68096 0.34658 0.48318 0.17457  -0.00955 0.04029  59  ASP A CG    
520  O OD1   . ASP A 61  ? 0.70168 0.34637 0.50178 0.15261  -0.01063 0.04409  59  ASP A OD1   
521  O OD2   . ASP A 61  ? 0.74520 0.39062 0.52936 0.18734  -0.01226 0.03542  59  ASP A OD2   
522  N N     . ALA A 62  ? 0.48630 0.32831 0.37965 0.17244  0.00210  0.04288  60  ALA A N     
523  C CA    . ALA A 62  ? 0.46501 0.35106 0.37657 0.17426  0.00176  0.04696  60  ALA A CA    
524  C C     . ALA A 62  ? 0.45263 0.35406 0.37909 0.15055  0.00264  0.04755  60  ALA A C     
525  O O     . ALA A 62  ? 0.45500 0.36975 0.38366 0.14814  0.00071  0.05297  60  ALA A O     
526  C CB    . ALA A 62  ? 0.45537 0.38311 0.38408 0.18597  0.00342  0.04322  60  ALA A CB    
527  N N     . LEU A 63  ? 0.41038 0.31009 0.34552 0.13444  0.00530  0.04179  61  LEU A N     
528  C CA    . LEU A 63  ? 0.37304 0.28410 0.31943 0.11468  0.00640  0.04195  61  LEU A CA    
529  C C     . LEU A 63  ? 0.44332 0.32947 0.37541 0.10711  0.00602  0.04882  61  LEU A C     
530  O O     . LEU A 63  ? 0.43190 0.33247 0.36832 0.09952  0.00622  0.05204  61  LEU A O     
531  C CB    . LEU A 63  ? 0.33860 0.25041 0.29495 0.10153  0.00905  0.03514  61  LEU A CB    
532  C CG    . LEU A 63  ? 0.34511 0.26968 0.31280 0.08406  0.01047  0.03445  61  LEU A CG    
533  C CD1   . LEU A 63  ? 0.37121 0.32667 0.35021 0.08466  0.00869  0.03475  61  LEU A CD1   
534  C CD2   . LEU A 63  ? 0.34959 0.27697 0.32716 0.07419  0.01247  0.02808  61  LEU A CD2   
535  N N     . ALA A 64  ? 0.45630 0.30406 0.36959 0.10851  0.00518  0.05140  62  ALA A N     
536  C CA    . ALA A 64  ? 0.49050 0.31394 0.38932 0.09930  0.00466  0.06011  62  ALA A CA    
537  C C     . ALA A 64  ? 0.50902 0.33854 0.39998 0.10992  0.00268  0.06817  62  ALA A C     
538  O O     . ALA A 64  ? 0.51758 0.35087 0.40621 0.10046  0.00375  0.07482  62  ALA A O     
539  C CB    . ALA A 64  ? 0.52402 0.30068 0.40130 0.09859  0.00215  0.06178  62  ALA A CB    
540  N N     . ALA A 65  ? 0.47045 0.30343 0.35678 0.13065  -0.00012 0.06804  63  ALA A N     
541  C CA    . ALA A 65  ? 0.51985 0.35782 0.39697 0.14344  -0.00318 0.07617  63  ALA A CA    
542  C C     . ALA A 65  ? 0.48730 0.36920 0.38179 0.14043  -0.00354 0.07548  63  ALA A C     
543  O O     . ALA A 65  ? 0.50715 0.39442 0.39380 0.14491  -0.00603 0.08271  63  ALA A O     
544  C CB    . ALA A 65  ? 0.53724 0.36743 0.40414 0.16890  -0.00628 0.07618  63  ALA A CB    
545  N N     . ALA A 66  ? 0.46156 0.37214 0.37707 0.13261  -0.00194 0.06711  64  ALA A N     
546  C CA    . ALA A 66  ? 0.45042 0.39848 0.38040 0.12878  -0.00400 0.06519  64  ALA A CA    
547  C C     . ALA A 66  ? 0.47500 0.42149 0.39934 0.11644  -0.00303 0.06850  64  ALA A C     
548  O O     . ALA A 66  ? 0.44077 0.36468 0.35675 0.10668  0.00079  0.07135  64  ALA A O     
549  C CB    . ALA A 66  ? 0.44484 0.41562 0.39532 0.12036  -0.00273 0.05618  64  ALA A CB    
550  N N     . SER A 67  ? 0.48611 0.45863 0.41439 0.11683  -0.00682 0.06836  65  SER A N     
551  C CA    . SER A 67  ? 0.43455 0.41013 0.35777 0.10617  -0.00552 0.06899  65  SER A CA    
552  C C     . SER A 67  ? 0.40600 0.38904 0.34219 0.09249  -0.00235 0.06009  65  SER A C     
553  O O     . SER A 67  ? 0.40369 0.39910 0.35457 0.09070  -0.00373 0.05319  65  SER A O     
554  C CB    . SER A 67  ? 0.45624 0.45449 0.37608 0.11133  -0.01188 0.07036  65  SER A CB    
555  O OG    . SER A 67  ? 0.46943 0.49385 0.40463 0.10711  -0.01648 0.06210  65  SER A OG    
556  N N     . THR A 68  ? 0.43842 0.41481 0.36851 0.08343  0.00219  0.06123  66  THR A N     
557  C CA    . THR A 68  ? 0.42342 0.40734 0.36379 0.07314  0.00507  0.05318  66  THR A CA    
558  C C     . THR A 68  ? 0.37646 0.38074 0.32277 0.07284  -0.00063 0.04529  66  THR A C     
559  O O     . THR A 68  ? 0.34732 0.35724 0.30546 0.06732  -0.00130 0.03777  66  THR A O     
560  C CB    . THR A 68  ? 0.45799 0.43673 0.38991 0.06627  0.01122  0.05719  66  THR A CB    
561  O OG1   . THR A 68  ? 0.49013 0.44845 0.41734 0.06290  0.01501  0.06517  66  THR A OG1   
562  C CG2   . THR A 68  ? 0.47216 0.46017 0.41355 0.05880  0.01429  0.04898  66  THR A CG2   
563  N N     . ALA A 69  ? 0.36822 0.38216 0.30505 0.07804  -0.00584 0.04732  67  ALA A N     
564  C CA    . ALA A 69  ? 0.35765 0.38844 0.29763 0.07588  -0.01350 0.03998  67  ALA A CA    
565  C C     . ALA A 69  ? 0.37120 0.41391 0.32809 0.07472  -0.01814 0.03689  67  ALA A C     
566  O O     . ALA A 69  ? 0.39064 0.44056 0.35505 0.06688  -0.02204 0.02970  67  ALA A O     
567  C CB    . ALA A 69  ? 0.39866 0.43860 0.32486 0.08209  -0.01974 0.04365  67  ALA A CB    
568  N N     . ASP A 70  ? 0.37227 0.41723 0.33382 0.08308  -0.01795 0.04274  68  ASP A N     
569  C CA    . ASP A 70  ? 0.36308 0.42436 0.34111 0.08330  -0.02091 0.04087  68  ASP A CA    
570  C C     . ASP A 70  ? 0.36835 0.42174 0.35676 0.07518  -0.01595 0.03545  68  ASP A C     
571  O O     . ASP A 70  ? 0.32304 0.39080 0.32390 0.06873  -0.01923 0.03166  68  ASP A O     
572  C CB    . ASP A 70  ? 0.37960 0.44431 0.35816 0.09775  -0.02051 0.04782  68  ASP A CB    
573  C CG    . ASP A 70  ? 0.43772 0.52143 0.41174 0.10667  -0.02785 0.05320  68  ASP A CG    
574  O OD1   . ASP A 70  ? 0.48134 0.57879 0.45396 0.09956  -0.03451 0.05073  68  ASP A OD1   
575  O OD2   . ASP A 70  ? 0.48806 0.57174 0.45836 0.12159  -0.02759 0.05965  68  ASP A OD2   
576  N N     . VAL A 71  ? 0.33182 0.36345 0.31521 0.07451  -0.00865 0.03597  69  VAL A N     
577  C CA    . VAL A 71  ? 0.32467 0.34985 0.31725 0.06721  -0.00453 0.03105  69  VAL A CA    
578  C C     . VAL A 71  ? 0.32330 0.35244 0.31847 0.05715  -0.00652 0.02446  69  VAL A C     
579  O O     . VAL A 71  ? 0.32622 0.36122 0.33176 0.05121  -0.00805 0.02030  69  VAL A O     
580  C CB    . VAL A 71  ? 0.33816 0.34063 0.32418 0.06703  0.00221  0.03357  69  VAL A CB    
581  C CG1   . VAL A 71  ? 0.33268 0.33079 0.32812 0.05951  0.00555  0.02844  69  VAL A CG1   
582  C CG2   . VAL A 71  ? 0.37406 0.36568 0.35346 0.07787  0.00264  0.03924  69  VAL A CG2   
583  N N     . LEU A 72  ? 0.30671 0.33192 0.29038 0.05615  -0.00687 0.02362  70  LEU A N     
584  C CA    . LEU A 72  ? 0.32343 0.34853 0.30494 0.04972  -0.00944 0.01631  70  LEU A CA    
585  C C     . LEU A 72  ? 0.31237 0.34936 0.29841 0.04501  -0.01900 0.01272  70  LEU A C     
586  O O     . LEU A 72  ? 0.33368 0.36747 0.32318 0.03770  -0.02184 0.00708  70  LEU A O     
587  C CB    . LEU A 72  ? 0.34294 0.36354 0.30831 0.05254  -0.00782 0.01606  70  LEU A CB    
588  C CG    . LEU A 72  ? 0.32543 0.33786 0.28722 0.05342  0.00164  0.01996  70  LEU A CG    
589  C CD1   . LEU A 72  ? 0.34357 0.35762 0.28847 0.05752  0.00342  0.02172  70  LEU A CD1   
590  C CD2   . LEU A 72  ? 0.33817 0.34698 0.30804 0.04868  0.00551  0.01489  70  LEU A CD2   
591  N N     . ALA A 73  ? 0.32801 0.37893 0.31345 0.04843  -0.02483 0.01667  71  ALA A N     
592  C CA    . ALA A 73  ? 0.37148 0.43840 0.36318 0.04145  -0.03496 0.01493  71  ALA A CA    
593  C C     . ALA A 73  ? 0.33623 0.41158 0.34520 0.03552  -0.03434 0.01552  71  ALA A C     
594  O O     . ALA A 73  ? 0.33036 0.40871 0.34337 0.02438  -0.04084 0.01227  71  ALA A O     
595  C CB    . ALA A 73  ? 0.36732 0.45362 0.35827 0.04757  -0.04075 0.02085  71  ALA A CB    
596  N N     . GLN A 74  ? 0.29296 0.37054 0.31010 0.04272  -0.02702 0.01989  72  GLN A N     
597  C CA    . GLN A 74  ? 0.32155 0.40829 0.35325 0.03915  -0.02509 0.02074  72  GLN A CA    
598  C C     . GLN A 74  ? 0.30142 0.37188 0.33360 0.03029  -0.02283 0.01532  72  GLN A C     
599  O O     . GLN A 74  ? 0.32932 0.40767 0.37124 0.02246  -0.02480 0.01542  72  GLN A O     
600  C CB    . GLN A 74  ? 0.37490 0.46175 0.40946 0.05138  -0.01777 0.02499  72  GLN A CB    
601  C CG    . GLN A 74  ? 0.38632 0.49556 0.42439 0.06207  -0.02047 0.03118  72  GLN A CG    
602  C CD    . GLN A 74  ? 0.43887 0.57880 0.49330 0.05762  -0.02383 0.03376  72  GLN A CD    
603  O OE1   . GLN A 74  ? 0.45252 0.59429 0.51458 0.05647  -0.01913 0.03330  72  GLN A OE1   
604  N NE2   . GLN A 74  ? 0.44512 0.61106 0.50490 0.05423  -0.03211 0.03714  72  GLN A NE2   
605  N N     . TRP A 75  ? 0.26677 0.31682 0.28854 0.03173  -0.01876 0.01156  73  TRP A N     
606  C CA    . TRP A 75  ? 0.28034 0.31621 0.30227 0.02651  -0.01597 0.00692  73  TRP A CA    
607  C C     . TRP A 75  ? 0.27892 0.30787 0.29471 0.01832  -0.02348 0.00150  73  TRP A C     
608  O O     . TRP A 75  ? 0.30094 0.32045 0.31855 0.01331  -0.02341 -0.00137 73  TRP A O     
609  C CB    . TRP A 75  ? 0.27063 0.29241 0.28476 0.03176  -0.00864 0.00603  73  TRP A CB    
610  C CG    . TRP A 75  ? 0.24703 0.26025 0.26562 0.02915  -0.00399 0.00366  73  TRP A CG    
611  C CD1   . TRP A 75  ? 0.29176 0.29590 0.30571 0.02737  -0.00381 -0.00120 73  TRP A CD1   
612  C CD2   . TRP A 75  ? 0.26093 0.27396 0.28787 0.02951  0.00070  0.00585  73  TRP A CD2   
613  N NE1   . TRP A 75  ? 0.28869 0.28977 0.30983 0.02600  0.00062  -0.00125 73  TRP A NE1   
614  C CE2   . TRP A 75  ? 0.27117 0.27702 0.29983 0.02640  0.00314  0.00274  73  TRP A CE2   
615  C CE3   . TRP A 75  ? 0.28685 0.30438 0.31815 0.03362  0.00267  0.00969  73  TRP A CE3   
616  C CZ2   . TRP A 75  ? 0.27953 0.28350 0.31455 0.02544  0.00689  0.00349  73  TRP A CZ2   
617  C CZ3   . TRP A 75  ? 0.28404 0.29666 0.31963 0.03345  0.00665  0.00947  73  TRP A CZ3   
618  C CH2   . TRP A 75  ? 0.27643 0.28280 0.31408 0.02844  0.00842  0.00646  73  TRP A CH2   
619  N N     A GLN A 76  ? 0.29951 0.33025 0.30576 0.01726  -0.03069 -0.00014 74  GLN A N     
620  N N     B GLN A 76  ? 0.30005 0.33066 0.30614 0.01740  -0.03061 -0.00016 74  GLN A N     
621  C CA    A GLN A 76  ? 0.32240 0.33793 0.31572 0.01152  -0.03819 -0.00715 74  GLN A CA    
622  C CA    B GLN A 76  ? 0.32212 0.33881 0.31590 0.01092  -0.03887 -0.00691 74  GLN A CA    
623  C C     A GLN A 76  ? 0.32081 0.33361 0.32073 -0.00057 -0.04442 -0.00755 74  GLN A C     
624  C C     B GLN A 76  ? 0.32157 0.33490 0.32242 -0.00070 -0.04412 -0.00727 74  GLN A C     
625  O O     A GLN A 76  ? 0.30767 0.33896 0.31942 -0.00840 -0.04907 -0.00220 74  GLN A O     
626  O O     B GLN A 76  ? 0.30829 0.34005 0.32201 -0.00822 -0.04783 -0.00169 74  GLN A O     
627  C CB    A GLN A 76  ? 0.31867 0.33792 0.29978 0.01133  -0.04665 -0.00877 74  GLN A CB    
628  C CB    B GLN A 76  ? 0.32305 0.34663 0.30737 0.00914  -0.04828 -0.00760 74  GLN A CB    
629  C CG    A GLN A 76  ? 0.35038 0.36814 0.32018 0.02316  -0.04055 -0.00846 74  GLN A CG    
630  C CG    B GLN A 76  ? 0.37693 0.37972 0.33902 0.00919  -0.05455 -0.01646 74  GLN A CG    
631  C CD    A GLN A 76  ? 0.39704 0.39865 0.35807 0.02950  -0.03248 -0.01282 74  GLN A CD    
632  C CD    B GLN A 76  ? 0.39105 0.40134 0.34202 0.00807  -0.06406 -0.01726 74  GLN A CD    
633  O OE1   A GLN A 76  ? 0.41711 0.40318 0.36482 0.02929  -0.03626 -0.02046 74  GLN A OE1   
634  O OE1   B GLN A 76  ? 0.44635 0.45758 0.38592 0.01805  -0.06067 -0.01753 74  GLN A OE1   
635  N NE2   A GLN A 76  ? 0.38157 0.38687 0.34930 0.03531  -0.02187 -0.00776 74  GLN A NE2   
636  N NE2   B GLN A 76  ? 0.35318 0.37069 0.30744 -0.00512 -0.07646 -0.01669 74  GLN A NE2   
637  N N     . GLY A 77  ? 0.33447 0.32556 0.32640 -0.00154 -0.04431 -0.01297 75  GLY A N     
638  C CA    . GLY A 77  ? 0.33724 0.31930 0.33209 -0.01249 -0.04974 -0.01283 75  GLY A CA    
639  C C     . GLY A 77  ? 0.31655 0.29632 0.32075 -0.00951 -0.04121 -0.01090 75  GLY A C     
640  O O     . GLY A 77  ? 0.34279 0.30714 0.34376 -0.01524 -0.04471 -0.01211 75  GLY A O     
641  N N     . LEU A 78  ? 0.28409 0.27619 0.29760 -0.00083 -0.03097 -0.00794 76  LEU A N     
642  C CA    . LEU A 78  ? 0.26795 0.25784 0.28879 0.00196  -0.02358 -0.00680 76  LEU A CA    
643  C C     . LEU A 78  ? 0.31144 0.28484 0.32238 0.00929  -0.02026 -0.01223 76  LEU A C     
644  O O     . LEU A 78  ? 0.28115 0.24988 0.29583 0.00998  -0.01724 -0.01210 76  LEU A O     
645  C CB    . LEU A 78  ? 0.25133 0.25653 0.28276 0.00764  -0.01543 -0.00229 76  LEU A CB    
646  C CG    . LEU A 78  ? 0.26463 0.28901 0.30822 0.00401  -0.01601 0.00360  76  LEU A CG    
647  C CD1   . LEU A 78  ? 0.25425 0.28710 0.30206 0.01309  -0.00896 0.00640  76  LEU A CD1   
648  C CD2   . LEU A 78  ? 0.27729 0.30146 0.32714 -0.00256 -0.01614 0.00539  76  LEU A CD2   
649  N N     . GLY A 79  ? 0.32916 0.29632 0.32736 0.01579  -0.02055 -0.01660 77  GLY A N     
650  C CA    . GLY A 79  ? 0.31047 0.26815 0.29980 0.02505  -0.01630 -0.02108 77  GLY A CA    
651  C C     . GLY A 79  ? 0.30513 0.27630 0.30337 0.03047  -0.00601 -0.01726 77  GLY A C     
652  O O     . GLY A 79  ? 0.28067 0.26266 0.29000 0.02733  -0.00257 -0.01196 77  GLY A O     
653  N N     . TYR A 80  ? 0.29827 0.26844 0.29053 0.03887  -0.00149 -0.01985 78  TYR A N     
654  C CA    . TYR A 80  ? 0.30555 0.29008 0.30561 0.04196  0.00750  -0.01547 78  TYR A CA    
655  C C     . TYR A 80  ? 0.29561 0.28861 0.29941 0.03853  0.01024  -0.00977 78  TYR A C     
656  O O     . TYR A 80  ? 0.26570 0.26298 0.27971 0.03386  0.01286  -0.00503 78  TYR A O     
657  C CB    . TYR A 80  ? 0.28128 0.26902 0.29360 0.03921  0.00981  -0.01344 78  TYR A CB    
658  C CG    . TYR A 80  ? 0.32184 0.30501 0.32985 0.04645  0.00935  -0.01745 78  TYR A CG    
659  C CD1   . TYR A 80  ? 0.32589 0.30240 0.31886 0.05670  0.00828  -0.02288 78  TYR A CD1   
660  C CD2   . TYR A 80  ? 0.28090 0.26548 0.29791 0.04466  0.00956  -0.01601 78  TYR A CD2   
661  C CE1   . TYR A 80  ? 0.32516 0.29595 0.31196 0.06665  0.00776  -0.02677 78  TYR A CE1   
662  C CE2   . TYR A 80  ? 0.26860 0.24909 0.28100 0.05318  0.00873  -0.01899 78  TYR A CE2   
663  C CZ    . TYR A 80  ? 0.30111 0.27433 0.29838 0.06496  0.00794  -0.02435 78  TYR A CZ    
664  O OH    . TYR A 80  ? 0.33416 0.30185 0.32447 0.07685  0.00705  -0.02764 78  TYR A OH    
665  N N     . ASN A 81  ? 0.29843 0.29124 0.29079 0.04209  0.00888  -0.01070 79  ASN A N     
666  C CA    . ASN A 81  ? 0.31016 0.30763 0.30230 0.04030  0.00913  -0.00555 79  ASN A CA    
667  C C     . ASN A 81  ? 0.28936 0.29413 0.28500 0.04008  0.01683  0.00170  79  ASN A C     
668  O O     . ASN A 81  ? 0.29101 0.29538 0.28672 0.03862  0.01696  0.00700  79  ASN A O     
669  C CB    . ASN A 81  ? 0.31523 0.31050 0.29209 0.04437  0.00458  -0.00871 79  ASN A CB    
670  C CG    . ASN A 81  ? 0.36186 0.34700 0.33373 0.04120  -0.00526 -0.01527 79  ASN A CG    
671  O OD1   . ASN A 81  ? 0.36550 0.35275 0.34550 0.03443  -0.01036 -0.01331 79  ASN A OD1   
672  N ND2   . ASN A 81  ? 0.34523 0.31923 0.30269 0.04607  -0.00827 -0.02270 79  ASN A ND2   
673  N N     . ARG A 82  ? 0.24251 0.25406 0.24049 0.04123  0.02267  0.00281  80  ARG A N     
674  C CA    . ARG A 82  ? 0.30142 0.31911 0.30457 0.03651  0.02848  0.01095  80  ARG A CA    
675  C C     . ARG A 82  ? 0.29075 0.29987 0.30249 0.02997  0.02662  0.01329  80  ARG A C     
676  O O     . ARG A 82  ? 0.28080 0.28610 0.29176 0.02580  0.02865  0.01982  80  ARG A O     
677  C CB    . ARG A 82  ? 0.28036 0.31185 0.28879 0.03670  0.03408  0.01238  80  ARG A CB    
678  C CG    . ARG A 82  ? 0.30947 0.35372 0.30828 0.04499  0.03837  0.01214  80  ARG A CG    
679  C CD    . ARG A 82  ? 0.32243 0.38376 0.32839 0.04830  0.04296  0.01197  80  ARG A CD    
680  N NE    . ARG A 82  ? 0.33888 0.41846 0.33618 0.05748  0.04915  0.01356  80  ARG A NE    
681  C CZ    . ARG A 82  ? 0.35074 0.45049 0.35175 0.06496  0.05398  0.01330  80  ARG A CZ    
682  N NH1   . ARG A 82  ? 0.36473 0.46776 0.37794 0.06381  0.05257  0.01159  80  ARG A NH1   
683  N NH2   . ARG A 82  ? 0.38692 0.50574 0.37845 0.07527  0.06041  0.01493  80  ARG A NH2   
684  N N     . ARG A 83  ? 0.25965 0.26425 0.27760 0.02928  0.02265  0.00826  81  ARG A N     
685  C CA    . ARG A 83  ? 0.26826 0.26626 0.29237 0.02536  0.02139  0.00962  81  ARG A CA    
686  C C     . ARG A 83  ? 0.29372 0.28566 0.31258 0.02756  0.01986  0.01309  81  ARG A C     
687  O O     . ARG A 83  ? 0.29430 0.27767 0.31265 0.02623  0.02054  0.01616  81  ARG A O     
688  C CB    . ARG A 83  ? 0.25530 0.25271 0.28545 0.02494  0.01767  0.00469  81  ARG A CB    
689  C CG    . ARG A 83  ? 0.24112 0.24190 0.27567 0.02412  0.01862  0.00191  81  ARG A CG    
690  C CD    . ARG A 83  ? 0.27729 0.27495 0.31618 0.02265  0.01466  -0.00110 81  ARG A CD    
691  N NE    . ARG A 83  ? 0.26353 0.25795 0.29759 0.02369  0.00970  -0.00386 81  ARG A NE    
692  C CZ    . ARG A 83  ? 0.27636 0.26903 0.31336 0.02011  0.00541  -0.00445 81  ARG A CZ    
693  N NH1   . ARG A 83  ? 0.25622 0.25189 0.30038 0.01739  0.00644  -0.00251 81  ARG A NH1   
694  N NH2   . ARG A 83  ? 0.28147 0.26898 0.31279 0.01854  -0.00041 -0.00679 81  ARG A NH2   
695  N N     . ALA A 84  ? 0.28433 0.27948 0.29763 0.03179  0.01697  0.01236  82  ALA A N     
696  C CA    . ALA A 84  ? 0.31079 0.30354 0.31950 0.03586  0.01487  0.01611  82  ALA A CA    
697  C C     . ALA A 84  ? 0.32261 0.30727 0.32293 0.03615  0.01837  0.02305  82  ALA A C     
698  O O     . ALA A 84  ? 0.31800 0.29231 0.31475 0.03867  0.01789  0.02688  82  ALA A O     
699  C CB    . ALA A 84  ? 0.30328 0.30375 0.30757 0.03899  0.00991  0.01410  82  ALA A CB    
700  N N     . LEU A 85  ? 0.29307 0.28184 0.28879 0.03401  0.02190  0.02523  83  LEU A N     
701  C CA    . LEU A 85  ? 0.33059 0.31313 0.31827 0.03154  0.02539  0.03384  83  LEU A CA    
702  C C     . LEU A 85  ? 0.34719 0.31838 0.33849 0.02392  0.02694  0.03690  83  LEU A C     
703  O O     . LEU A 85  ? 0.35050 0.30563 0.33347 0.02215  0.02654  0.04341  83  LEU A O     
704  C CB    . LEU A 85  ? 0.33225 0.32765 0.31535 0.03080  0.02984  0.03618  83  LEU A CB    
705  C CG    . LEU A 85  ? 0.36189 0.36538 0.33620 0.03852  0.02780  0.03262  83  LEU A CG    
706  C CD1   . LEU A 85  ? 0.34165 0.35850 0.30929 0.03967  0.03366  0.03511  83  LEU A CD1   
707  C CD2   . LEU A 85  ? 0.36886 0.36587 0.33358 0.04324  0.02398  0.03694  83  LEU A CD2   
708  N N     . ALA A 86  ? 0.28840 0.26570 0.29008 0.01915  0.02788  0.03246  84  ALA A N     
709  C CA    . ALA A 86  ? 0.31764 0.28494 0.32165 0.01041  0.02814  0.03501  84  ALA A CA    
710  C C     . ALA A 86  ? 0.30186 0.24971 0.30187 0.01368  0.02425  0.03268  84  ALA A C     
711  O O     . ALA A 86  ? 0.35649 0.28472 0.34849 0.00905  0.02293  0.03659  84  ALA A O     
712  C CB    . ALA A 86  ? 0.33041 0.31177 0.34635 0.00578  0.02944  0.03095  84  ALA A CB    
713  N N     . LEU A 87  ? 0.29503 0.24786 0.29930 0.02162  0.02213  0.02653  85  LEU A N     
714  C CA    . LEU A 87  ? 0.31680 0.25688 0.31706 0.02807  0.01948  0.02454  85  LEU A CA    
715  C C     . LEU A 87  ? 0.35492 0.27941 0.34163 0.03449  0.01829  0.03019  85  LEU A C     
716  O O     . LEU A 87  ? 0.36808 0.27038 0.34450 0.03702  0.01663  0.03121  85  LEU A O     
717  C CB    . LEU A 87  ? 0.31663 0.27227 0.32547 0.03431  0.01795  0.01928  85  LEU A CB    
718  C CG    . LEU A 87  ? 0.31718 0.26960 0.32430 0.04333  0.01631  0.01751  85  LEU A CG    
719  C CD1   . LEU A 87  ? 0.34757 0.28353 0.35018 0.04167  0.01653  0.01492  85  LEU A CD1   
720  C CD2   . LEU A 87  ? 0.33615 0.31016 0.35441 0.04532  0.01497  0.01444  85  LEU A CD2   
721  N N     . LYS A 88  ? 0.32862 0.26208 0.31264 0.03810  0.01850  0.03380  86  LYS A N     
722  C CA    . LYS A 88  ? 0.35778 0.27653 0.32786 0.04522  0.01698  0.04023  86  LYS A CA    
723  C C     . LYS A 88  ? 0.40132 0.29658 0.35960 0.03679  0.01783  0.04737  86  LYS A C     
724  O O     . LYS A 88  ? 0.41564 0.28509 0.35963 0.04164  0.01530  0.05101  86  LYS A O     
725  C CB    . LYS A 88  ? 0.37994 0.31427 0.34839 0.04992  0.01643  0.04291  86  LYS A CB    
726  C CG    . LYS A 88  ? 0.42218 0.34490 0.37717 0.06067  0.01379  0.04920  86  LYS A CG    
727  C CD    . LYS A 88  ? 0.37360 0.30954 0.32370 0.06285  0.01320  0.05330  86  LYS A CD    
728  C CE    . LYS A 88  ? 0.45848 0.38897 0.39716 0.07623  0.00929  0.05902  86  LYS A CE    
729  N NZ    . LYS A 88  ? 0.45397 0.35396 0.37935 0.08162  0.00865  0.06422  86  LYS A NZ    
730  N N     . ARG A 89  ? 0.38823 0.29206 0.35145 0.02417  0.02101  0.05005  87  ARG A N     
731  C CA    . ARG A 89  ? 0.42941 0.31511 0.38338 0.01225  0.02142  0.05855  87  ARG A CA    
732  C C     . ARG A 89  ? 0.43439 0.29400 0.38297 0.00814  0.01762  0.05571  87  ARG A C     
733  O O     . ARG A 89  ? 0.45784 0.28710 0.39022 0.00401  0.01455  0.06183  87  ARG A O     
734  C CB    . ARG A 89  ? 0.43580 0.34404 0.39987 -0.00024 0.02597  0.06175  87  ARG A CB    
735  C CG    . ARG A 89  ? 0.71749 0.63099 0.67390 -0.00568 0.02938  0.07321  87  ARG A CG    
736  C CD    . ARG A 89  ? 0.72825 0.67385 0.69737 -0.01278 0.03504  0.07415  87  ARG A CD    
737  N NE    . ARG A 89  ? 0.69088 0.65892 0.66058 -0.00237 0.03848  0.07157  87  ARG A NE    
738  C CZ    . ARG A 89  ? 0.71029 0.70247 0.69052 0.00122  0.04136  0.06467  87  ARG A CZ    
739  N NH1   . ARG A 89  ? 0.72779 0.72759 0.72088 -0.00366 0.04141  0.05990  87  ARG A NH1   
740  N NH2   . ARG A 89  ? 0.70366 0.71052 0.67928 0.01087  0.04346  0.06214  87  ARG A NH2   
741  N N     . THR A 90  ? 0.38951 0.25834 0.34932 0.00871  0.01721  0.04655  88  THR A N     
742  C CA    . THR A 90  ? 0.41690 0.26139 0.36950 0.00629  0.01320  0.04231  88  THR A CA    
743  C C     . THR A 90  ? 0.46047 0.27642 0.39509 0.02064  0.00975  0.04152  88  THR A C     
744  O O     . THR A 90  ? 0.47730 0.25804 0.39410 0.01768  0.00541  0.04307  88  THR A O     
745  C CB    . THR A 90  ? 0.41443 0.27736 0.38152 0.00719  0.01382  0.03298  88  THR A CB    
746  O OG1   . THR A 90  ? 0.41284 0.29132 0.39110 -0.00749 0.01518  0.03459  88  THR A OG1   
747  C CG2   . THR A 90  ? 0.41108 0.25094 0.36795 0.01248  0.00990  0.02636  88  THR A CG2   
748  N N     . ALA A 91  ? 0.45230 0.28259 0.39005 0.03653  0.01099  0.03954  89  ALA A N     
749  C CA    . ALA A 91  ? 0.44790 0.25705 0.36955 0.05343  0.00822  0.03980  89  ALA A CA    
750  C C     . ALA A 91  ? 0.49701 0.27626 0.39885 0.05189  0.00582  0.04964  89  ALA A C     
751  O O     . ALA A 91  ? 0.49538 0.23752 0.37616 0.05886  0.00164  0.05018  89  ALA A O     
752  C CB    . ALA A 91  ? 0.43951 0.27819 0.37172 0.06834  0.00971  0.03775  89  ALA A CB    
753  N N     . GLU A 92  ? 0.46646 0.25923 0.37235 0.04316  0.00823  0.05774  90  GLU A N     
754  C CA    . GLU A 92  ? 0.49758 0.26359 0.38424 0.04029  0.00628  0.06911  90  GLU A CA    
755  C C     . GLU A 92  ? 0.58015 0.31048 0.45312 0.02390  0.00270  0.07298  90  GLU A C     
756  O O     . GLU A 92  ? 0.60244 0.29187 0.45156 0.02614  -0.00213 0.07879  90  GLU A O     
757  C CB    . GLU A 92  ? 0.49639 0.28888 0.39042 0.03360  0.01048  0.07696  90  GLU A CB    
758  C CG    . GLU A 92  ? 0.50628 0.32539 0.40684 0.04936  0.01144  0.07461  90  GLU A CG    
759  C CD    . GLU A 92  ? 0.54561 0.39287 0.45327 0.04309  0.01545  0.07898  90  GLU A CD    
760  O OE1   . GLU A 92  ? 0.59399 0.44251 0.50190 0.02794  0.01863  0.08504  90  GLU A OE1   
761  O OE2   . GLU A 92  ? 0.50116 0.37026 0.41326 0.05338  0.01513  0.07652  90  GLU A OE2   
762  N N     . VAL A 93  ? 0.52431 0.26845 0.41097 0.00693  0.00405  0.07022  91  VAL A N     
763  C CA    . VAL A 93  ? 0.55409 0.26757 0.42932 -0.01130 -0.00079 0.07356  91  VAL A CA    
764  C C     . VAL A 93  ? 0.60890 0.28085 0.46420 -0.00124 -0.00749 0.06545  91  VAL A C     
765  O O     . VAL A 93  ? 0.69159 0.31739 0.52202 -0.00647 -0.01402 0.07022  91  VAL A O     
766  C CB    . VAL A 93  ? 0.58913 0.33289 0.48564 -0.02919 0.00169  0.07146  91  VAL A CB    
767  C CG1   . VAL A 93  ? 0.62967 0.34356 0.51571 -0.04694 -0.00530 0.07156  91  VAL A CG1   
768  C CG2   . VAL A 93  ? 0.55758 0.33438 0.46675 -0.03993 0.00778  0.08183  91  VAL A CG2   
769  N N     . CYS A 94  ? 0.56258 0.24897 0.42646 0.01370  -0.00618 0.05329  92  CYS A N     
770  C CA    . CYS A 94  ? 0.59252 0.24352 0.43687 0.02538  -0.01157 0.04442  92  CYS A CA    
771  C C     . CYS A 94  ? 0.65768 0.27629 0.47774 0.04628  -0.01435 0.04697  92  CYS A C     
772  O O     . CYS A 94  ? 0.70782 0.27824 0.50024 0.05182  -0.02098 0.04417  92  CYS A O     
773  C CB    . CYS A 94  ? 0.57014 0.25082 0.43070 0.03652  -0.00823 0.03248  92  CYS A CB    
774  S SG    . CYS A 94  ? 0.57144 0.27710 0.45261 0.01476  -0.00750 0.02811  92  CYS A SG    
775  N N     . SER A 95  ? 0.63666 0.27978 0.46481 0.05894  -0.01014 0.05200  93  SER A N     
776  C CA    . SER A 95  ? 0.63797 0.25447 0.44404 0.07997  -0.01294 0.05599  93  SER A CA    
777  C C     . SER A 95  ? 0.65632 0.22333 0.43558 0.06900  -0.01880 0.06692  93  SER A C     
778  O O     . SER A 95  ? 0.73024 0.26314 0.48730 0.08058  -0.02408 0.06521  93  SER A O     
779  C CB    . SER A 95  ? 0.56951 0.22721 0.39164 0.09242  -0.00817 0.06002  93  SER A CB    
780  O OG    . SER A 95  ? 0.71098 0.34746 0.51303 0.11441  -0.01116 0.06442  93  SER A OG    
781  N N     . ALA A 96  ? 0.69599 0.27274 0.48374 0.04446  -0.01730 0.07691  94  ALA A N     
782  C CA    . ALA A 96  ? 0.75692 0.29094 0.52050 0.03131  -0.02248 0.09023  94  ALA A CA    
783  C C     . ALA A 96  ? 0.76829 0.27312 0.52302 0.01167  -0.02927 0.08653  94  ALA A C     
784  O O     . ALA A 96  ? 0.87881 0.35171 0.61553 0.00617  -0.03506 0.09130  94  ALA A O     
785  C CB    . ALA A 96  ? 0.73335 0.30034 0.51249 0.01328  -0.01699 0.10324  94  ALA A CB    
786  N N     . GLU A 97  ? 0.77981 0.29514 0.54612 0.00099  -0.02922 0.07817  95  GLU A N     
787  C CA    . GLU A 97  ? 0.84312 0.33949 0.60472 -0.02204 -0.03583 0.07611  95  GLU A CA    
788  C C     . GLU A 97  ? 0.81465 0.29422 0.56739 -0.01197 -0.04062 0.05968  95  GLU A C     
789  O O     . GLU A 97  ? 0.92279 0.37548 0.66220 -0.02551 -0.04836 0.05694  95  GLU A O     
790  C CB    . GLU A 97  ? 0.83256 0.36048 0.61628 -0.04910 -0.03263 0.08243  95  GLU A CB    
791  C CG    . GLU A 97  ? 0.91750 0.45696 0.70566 -0.06925 -0.03029 0.10017  95  GLU A CG    
792  C CD    . GLU A 97  ? 0.99165 0.58212 0.80898 -0.08894 -0.02404 0.10493  95  GLU A CD    
793  O OE1   . GLU A 97  ? 1.02862 0.65918 0.86222 -0.08515 -0.01534 0.11149  95  GLU A OE1   
794  O OE2   . GLU A 97  ? 0.99618 0.59258 0.82203 -0.10568 -0.02760 0.10063  95  GLU A OE2   
795  N N     A ARG A 98  ? 0.80927 0.30512 0.56797 0.01144  -0.03630 0.04919  96  ARG A N     
796  N N     B ARG A 98  ? 0.80903 0.30522 0.56811 0.01078  -0.03633 0.04910  96  ARG A N     
797  C CA    A ARG A 98  ? 0.81542 0.30428 0.56839 0.02099  -0.03903 0.03401  96  ARG A CA    
798  C CA    B ARG A 98  ? 0.81659 0.30286 0.56802 0.02056  -0.03958 0.03396  96  ARG A CA    
799  C C     A ARG A 98  ? 0.81061 0.29217 0.54985 0.05340  -0.03809 0.02583  96  ARG A C     
800  C C     B ARG A 98  ? 0.80890 0.29399 0.55026 0.05398  -0.03733 0.02621  96  ARG A C     
801  O O     A ARG A 98  ? 0.82468 0.31363 0.56336 0.06727  -0.03709 0.01392  96  ARG A O     
802  O O     B ARG A 98  ? 0.81378 0.31386 0.55929 0.06907  -0.03474 0.01522  96  ARG A O     
803  C CB    A ARG A 98  ? 0.77747 0.30039 0.55321 0.01694  -0.03399 0.02881  96  ARG A CB    
804  C CB    B ARG A 98  ? 0.77964 0.29500 0.55170 0.01209  -0.03627 0.02807  96  ARG A CB    
805  C CG    A ARG A 98  ? 0.75376 0.28976 0.54389 -0.01449 -0.03616 0.03254  96  ARG A CG    
806  C CG    B ARG A 98  ? 0.80350 0.30507 0.56633 0.00955  -0.04197 0.01527  96  ARG A CG    
807  C CD    A ARG A 98  ? 0.72635 0.29938 0.53755 -0.01329 -0.03284 0.02174  96  ARG A CD    
808  C CD    B ARG A 98  ? 0.77654 0.31184 0.56212 -0.00031 -0.03880 0.01049  96  ARG A CD    
809  N NE    A ARG A 98  ? 0.77026 0.32211 0.56340 0.00887  -0.03497 0.00872  96  ARG A NE    
810  N NE    B ARG A 98  ? 0.77414 0.30203 0.56102 -0.03009 -0.04570 0.01271  96  ARG A NE    
811  C CZ    A ARG A 98  ? 0.75737 0.27505 0.52889 0.00545  -0.04317 0.00031  96  ARG A CZ    
812  C CZ    B ARG A 98  ? 0.77643 0.33722 0.58716 -0.05283 -0.04314 0.02301  96  ARG A CZ    
813  N NH1   A ARG A 98  ? 0.75132 0.25598 0.51972 -0.02110 -0.05067 0.00337  96  ARG A NH1   
814  N NH1   B ARG A 98  ? 0.71188 0.31233 0.54530 -0.04906 -0.03384 0.03088  96  ARG A NH1   
815  N NH2   A ARG A 98  ? 0.79348 0.30351 0.55122 0.02913  -0.04295 -0.01104 96  ARG A NH2   
816  N NH2   B ARG A 98  ? 0.75733 0.31250 0.56840 -0.07948 -0.05038 0.02539  96  ARG A NH2   
817  N N     . GLY A 99  ? 0.83997 0.31080 0.56865 0.06585  -0.03809 0.03266  97  GLY A N     
818  C CA    . GLY A 99  ? 0.84668 0.31722 0.56436 0.09683  -0.03682 0.02636  97  GLY A CA    
819  C C     . GLY A 99  ? 0.82201 0.33762 0.56045 0.11676  -0.02880 0.02175  97  GLY A C     
820  O O     . GLY A 99  ? 0.84931 0.37209 0.58142 0.14043  -0.02742 0.01403  97  GLY A O     
821  N N     . GLY A 100 ? 0.73074 0.27843 0.49326 0.10774  -0.02345 0.02680  98  GLY A N     
822  C CA    . GLY A 100 ? 0.71367 0.30563 0.49711 0.12459  -0.01640 0.02355  98  GLY A CA    
823  C C     . GLY A 100 ? 0.67135 0.28189 0.46613 0.12437  -0.01381 0.01293  98  GLY A C     
824  O O     . GLY A 100 ? 0.63269 0.28564 0.44586 0.13819  -0.00814 0.00949  98  GLY A O     
825  N N     . THR A 101 ? 0.70598 0.29367 0.49367 0.10610  -0.01798 0.00830  99  THR A N     
826  C CA    . THR A 101 ? 0.69356 0.30182 0.49214 0.10379  -0.01609 -0.00177 99  THR A CA    
827  C C     . THR A 101 ? 0.66179 0.28994 0.48151 0.07435  -0.01592 0.00068  99  THR A C     
828  O O     . THR A 101 ? 0.66576 0.27799 0.48319 0.05419  -0.01933 0.00842  99  THR A O     
829  C CB    . THR A 101 ? 0.78996 0.36272 0.56155 0.11085  -0.02191 -0.01201 99  THR A CB    
830  O OG1   . THR A 101 ? 0.80523 0.33953 0.56140 0.08797  -0.03024 -0.00983 99  THR A OG1   
831  C CG2   . THR A 101 ? 0.75350 0.32117 0.50917 0.13712  -0.02153 -0.01391 99  THR A CG2   
832  N N     . LEU A 102 ? 0.63317 0.29800 0.47327 0.07270  -0.01179 -0.00505 100 LEU A N     
833  C CA    . LEU A 102 ? 0.61356 0.29697 0.47164 0.04869  -0.01211 -0.00427 100 LEU A CA    
834  C C     . LEU A 102 ? 0.64227 0.28987 0.48066 0.03722  -0.02014 -0.01036 100 LEU A C     
835  O O     . LEU A 102 ? 0.65957 0.27558 0.47287 0.05150  -0.02397 -0.01863 100 LEU A O     
836  C CB    . LEU A 102 ? 0.57356 0.30505 0.45773 0.05171  -0.00579 -0.00771 100 LEU A CB    
837  C CG    . LEU A 102 ? 0.52037 0.28982 0.42739 0.05423  0.00038  -0.00118 100 LEU A CG    
838  C CD1   . LEU A 102 ? 0.51083 0.31830 0.43592 0.06231  0.00525  -0.00510 100 LEU A CD1   
839  C CD2   . LEU A 102 ? 0.49790 0.27959 0.41914 0.03381  0.00083  0.00583  100 LEU A CD2   
840  N N     . PRO A 103 ? 0.60484 0.25756 0.45313 0.01207  -0.02323 -0.00651 101 PRO A N     
841  C CA    . PRO A 103 ? 0.65959 0.28448 0.49212 -0.00184 -0.03206 -0.01238 101 PRO A CA    
842  C C     . PRO A 103 ? 0.63897 0.28364 0.47677 0.00648  -0.03055 -0.02292 101 PRO A C     
843  O O     . PRO A 103 ? 0.59225 0.27558 0.44957 0.01870  -0.02248 -0.02392 101 PRO A O     
844  C CB    . PRO A 103 ? 0.65943 0.29984 0.50867 -0.03065 -0.03422 -0.00316 101 PRO A CB    
845  C CG    . PRO A 103 ? 0.62684 0.30926 0.50276 -0.02910 -0.02484 0.00559  101 PRO A CG    
846  C CD    . PRO A 103 ? 0.58839 0.27571 0.46260 -0.00360 -0.01881 0.00347  101 PRO A CD    
847  N N     . ALA A 104 ? 0.71763 0.33386 0.53603 -0.00153 -0.03926 -0.03043 102 ALA A N     
848  C CA    . ALA A 104 ? 0.67693 0.30778 0.49556 0.00580  -0.03891 -0.04048 102 ALA A CA    
849  C C     . ALA A 104 ? 0.68644 0.32041 0.50909 -0.01825 -0.04665 -0.04175 102 ALA A C     
850  O O     . ALA A 104 ? 0.70284 0.32532 0.51036 -0.01584 -0.05179 -0.05154 102 ALA A O     
851  C CB    . ALA A 104 ? 0.68625 0.28029 0.47127 0.02878  -0.04157 -0.05172 102 ALA A CB    
852  N N     . THR A 105 ? 0.67701 0.32883 0.51940 -0.04088 -0.04769 -0.03174 103 THR A N     
853  C CA    . THR A 105 ? 0.67081 0.34551 0.52782 -0.06172 -0.05246 -0.03070 103 THR A CA    
854  C C     . THR A 105 ? 0.63094 0.35978 0.52454 -0.06554 -0.04342 -0.02188 103 THR A C     
855  O O     . THR A 105 ? 0.56951 0.30995 0.47431 -0.06120 -0.03637 -0.01446 103 THR A O     
856  C CB    . THR A 105 ? 0.71916 0.36473 0.56331 -0.08870 -0.06457 -0.02658 103 THR A CB    
857  O OG1   . THR A 105 ? 0.70664 0.35914 0.56284 -0.10052 -0.06156 -0.01337 103 THR A OG1   
858  C CG2   . THR A 105 ? 0.72412 0.30649 0.52671 -0.08480 -0.07497 -0.03564 103 THR A CG2   
859  N N     . ASN A 106 ? 0.54022 0.30063 0.45012 -0.07226 -0.04416 -0.02317 104 ASN A N     
860  C CA    . ASN A 106 ? 0.53930 0.34809 0.48067 -0.07326 -0.03634 -0.01615 104 ASN A CA    
861  C C     . ASN A 106 ? 0.54086 0.36105 0.49490 -0.08950 -0.03561 -0.00459 104 ASN A C     
862  O O     . ASN A 106 ? 0.49239 0.33526 0.46210 -0.08326 -0.02712 0.00143  104 ASN A O     
863  C CB    . ASN A 106 ? 0.51197 0.34759 0.46465 -0.07793 -0.03922 -0.01915 104 ASN A CB    
864  C CG    . ASN A 106 ? 0.47164 0.35293 0.45305 -0.07513 -0.03167 -0.01316 104 ASN A CG    
865  O OD1   . ASN A 106 ? 0.48162 0.38323 0.47857 -0.08564 -0.03003 -0.00463 104 ASN A OD1   
866  N ND2   . ASN A 106 ? 0.43792 0.33508 0.42497 -0.06087 -0.02729 -0.01723 104 ASN A ND2   
867  N N     . GLU A 107 ? 0.53522 0.33943 0.48101 -0.11111 -0.04490 -0.00108 105 GLU A N     
868  C CA    . GLU A 107 ? 0.53580 0.35588 0.49441 -0.12929 -0.04429 0.01175  105 GLU A CA    
869  C C     . GLU A 107 ? 0.59623 0.39891 0.54777 -0.12227 -0.03853 0.01754  105 GLU A C     
870  O O     . GLU A 107 ? 0.49589 0.32779 0.46491 -0.12362 -0.03112 0.02676  105 GLU A O     
871  C CB    . GLU A 107 ? 0.58604 0.38742 0.53384 -0.15610 -0.05701 0.01496  105 GLU A CB    
872  N N     . GLU A 108 ? 0.61109 0.36639 0.53547 -0.11323 -0.04201 0.01216  106 GLU A N     
873  C CA    . GLU A 108 ? 0.62552 0.36188 0.54075 -0.10529 -0.03767 0.01797  106 GLU A CA    
874  C C     . GLU A 108 ? 0.57605 0.34293 0.50772 -0.08406 -0.02617 0.01734  106 GLU A C     
875  O O     . GLU A 108 ? 0.54580 0.32065 0.48247 -0.08187 -0.02063 0.02545  106 GLU A O     
876  C CB    . GLU A 108 ? 0.68447 0.36269 0.56511 -0.09651 -0.04450 0.01135  106 GLU A CB    
877  C CG    . GLU A 108 ? 0.70761 0.34287 0.56520 -0.11908 -0.05733 0.01383  106 GLU A CG    
878  C CD    . GLU A 108 ? 0.84119 0.41506 0.66054 -0.10574 -0.06461 0.00440  106 GLU A CD    
879  O OE1   . GLU A 108 ? 0.84839 0.41356 0.65713 -0.09266 -0.06692 -0.00875 106 GLU A OE1   
880  O OE2   . GLU A 108 ? 0.87361 0.41981 0.67729 -0.10401 -0.06608 0.01001  106 GLU A OE2   
881  N N     . LEU A 109 ? 0.49775 0.28066 0.43622 -0.06901 -0.02311 0.00813  107 LEU A N     
882  C CA    . LEU A 109 ? 0.48564 0.29843 0.44042 -0.05260 -0.01374 0.00809  107 LEU A CA    
883  C C     . LEU A 109 ? 0.47030 0.32390 0.44956 -0.06081 -0.00862 0.01539  107 LEU A C     
884  O O     . LEU A 109 ? 0.43327 0.30240 0.42068 -0.05316 -0.00219 0.01940  107 LEU A O     
885  C CB    . LEU A 109 ? 0.43479 0.25583 0.39093 -0.03780 -0.01227 -0.00166 107 LEU A CB    
886  C CG    . LEU A 109 ? 0.45472 0.24357 0.38786 -0.02204 -0.01416 -0.00890 107 LEU A CG    
887  C CD1   . LEU A 109 ? 0.45336 0.25131 0.38603 -0.01322 -0.01419 -0.01769 107 LEU A CD1   
888  C CD2   . LEU A 109 ? 0.47993 0.27102 0.41321 -0.00564 -0.00822 -0.00626 107 LEU A CD2   
889  N N     . GLN A 110 ? 0.40401 0.27638 0.39419 -0.07511 -0.01168 0.01696  108 GLN A N     
890  C CA    . GLN A 110 ? 0.39377 0.30731 0.40630 -0.07956 -0.00638 0.02358  108 GLN A CA    
891  C C     . GLN A 110 ? 0.44347 0.36106 0.45715 -0.08912 -0.00361 0.03483  108 GLN A C     
892  O O     . GLN A 110 ? 0.42178 0.37206 0.45060 -0.08673 0.00297  0.03995  108 GLN A O     
893  C CB    . GLN A 110 ? 0.39869 0.33447 0.42277 -0.09163 -0.01081 0.02357  108 GLN A CB    
894  C CG    . GLN A 110 ? 0.40338 0.34881 0.43194 -0.07987 -0.01103 0.01458  108 GLN A CG    
895  C CD    . GLN A 110 ? 0.43151 0.41281 0.47790 -0.08606 -0.01224 0.01681  108 GLN A CD    
896  O OE1   . GLN A 110 ? 0.40554 0.41789 0.46765 -0.08665 -0.00733 0.02346  108 GLN A OE1   
897  N NE2   . GLN A 110 ? 0.43505 0.41339 0.47792 -0.08913 -0.01884 0.01124  108 GLN A NE2   
898  N N     . ALA A 111 ? 0.43546 0.31905 0.43131 -0.09915 -0.00860 0.03895  109 ALA A N     
899  C CA    . ALA A 111 ? 0.49171 0.37541 0.48557 -0.10837 -0.00603 0.05105  109 ALA A CA    
900  C C     . ALA A 111 ? 0.43678 0.31873 0.42721 -0.09074 0.00099  0.05169  109 ALA A C     
901  O O     . ALA A 111 ? 0.49463 0.38441 0.48533 -0.09541 0.00488  0.06191  109 ALA A O     
902  C CB    . ALA A 111 ? 0.61035 0.45154 0.58266 -0.12516 -0.01504 0.05566  109 ALA A CB    
903  N N     . LEU A 112 ? 0.43272 0.30776 0.42028 -0.07191 0.00246  0.04207  110 LEU A N     
904  C CA    . LEU A 112 ? 0.43203 0.30464 0.41526 -0.05665 0.00729  0.04295  110 LEU A CA    
905  C C     . LEU A 112 ? 0.37757 0.28813 0.37849 -0.04760 0.01428  0.04179  110 LEU A C     
906  O O     . LEU A 112 ? 0.37762 0.30896 0.39148 -0.04569 0.01506  0.03628  110 LEU A O     
907  C CB    . LEU A 112 ? 0.43520 0.28132 0.40492 -0.04079 0.00475  0.03438  110 LEU A CB    
908  C CG    . LEU A 112 ? 0.45497 0.25552 0.40033 -0.04451 -0.00213 0.03531  110 LEU A CG    
909  C CD1   . LEU A 112 ? 0.49220 0.27214 0.42543 -0.02831 -0.00480 0.02449  110 LEU A CD1   
910  C CD2   . LEU A 112 ? 0.51660 0.30042 0.44965 -0.04311 -0.00120 0.04483  110 LEU A CD2   
911  N N     . PRO A 113 ? 0.38880 0.30652 0.38819 -0.04135 0.01872  0.04669  111 PRO A N     
912  C CA    . PRO A 113 ? 0.34686 0.29609 0.35884 -0.03280 0.02427  0.04477  111 PRO A CA    
913  C C     . PRO A 113 ? 0.31943 0.27248 0.33658 -0.02003 0.02360  0.03439  111 PRO A C     
914  O O     . PRO A 113 ? 0.34417 0.28006 0.35389 -0.01172 0.02122  0.03027  111 PRO A O     
915  C CB    . PRO A 113 ? 0.39928 0.34731 0.40272 -0.02774 0.02740  0.05113  111 PRO A CB    
916  C CG    . PRO A 113 ? 0.45220 0.36909 0.43970 -0.03372 0.02386  0.05766  111 PRO A CG    
917  C CD    . PRO A 113 ? 0.40244 0.29976 0.38699 -0.04458 0.01830  0.05572  111 PRO A CD    
918  N N     . GLY A 114 ? 0.31260 0.28963 0.34224 -0.01812 0.02575  0.03101  112 GLY A N     
919  C CA    . GLY A 114 ? 0.29861 0.27978 0.33301 -0.00853 0.02481  0.02288  112 GLY A CA    
920  C C     . GLY A 114 ? 0.30275 0.27826 0.34008 -0.01110 0.02135  0.01803  112 GLY A C     
921  O O     . GLY A 114 ? 0.30670 0.28765 0.34860 -0.00487 0.02070  0.01268  112 GLY A O     
922  N N     . ILE A 115 ? 0.33038 0.29344 0.36332 -0.02073 0.01847  0.01997  113 ILE A N     
923  C CA    . ILE A 115 ? 0.31554 0.27065 0.34757 -0.02303 0.01438  0.01477  113 ILE A CA    
924  C C     . ILE A 115 ? 0.28056 0.25338 0.32254 -0.03377 0.01316  0.01701  113 ILE A C     
925  O O     . ILE A 115 ? 0.33065 0.30054 0.37077 -0.04663 0.01108  0.02241  113 ILE A O     
926  C CB    . ILE A 115 ? 0.31997 0.24426 0.33594 -0.02503 0.01024  0.01366  113 ILE A CB    
927  C CG1   . ILE A 115 ? 0.34268 0.25367 0.34947 -0.01214 0.01167  0.01256  113 ILE A CG1   
928  C CG2   . ILE A 115 ? 0.32544 0.24247 0.33819 -0.02631 0.00588  0.00712  113 ILE A CG2   
929  C CD1   . ILE A 115 ? 0.41595 0.29438 0.40398 -0.00931 0.00767  0.01045  113 ILE A CD1   
930  N N     . GLY A 116 ? 0.28385 0.27522 0.33598 -0.02895 0.01381  0.01366  114 GLY A N     
931  C CA    . GLY A 116 ? 0.28005 0.29049 0.34194 -0.03636 0.01187  0.01518  114 GLY A CA    
932  C C     . GLY A 116 ? 0.28077 0.28100 0.33857 -0.03903 0.00631  0.01000  114 GLY A C     
933  O O     . GLY A 116 ? 0.31741 0.29417 0.36312 -0.03610 0.00429  0.00565  114 GLY A O     
934  N N     . PRO A 117 ? 0.29612 0.31569 0.36311 -0.04311 0.00378  0.01043  115 PRO A N     
935  C CA    . PRO A 117 ? 0.30621 0.31726 0.36776 -0.04659 -0.00236 0.00568  115 PRO A CA    
936  C C     . PRO A 117 ? 0.31803 0.31636 0.37224 -0.03466 -0.00155 -0.00051 115 PRO A C     
937  O O     . PRO A 117 ? 0.34555 0.32567 0.38753 -0.03538 -0.00529 -0.00520 115 PRO A O     
938  C CB    . PRO A 117 ? 0.31491 0.35624 0.39041 -0.04958 -0.00424 0.00842  115 PRO A CB    
939  C CG    . PRO A 117 ? 0.35903 0.42312 0.44586 -0.05278 0.00009  0.01587  115 PRO A CG    
940  C CD    . PRO A 117 ? 0.28321 0.33493 0.36487 -0.04358 0.00625  0.01551  115 PRO A CD    
941  N N     . ALA A 118 ? 0.29253 0.30028 0.35270 -0.02393 0.00284  -0.00050 116 ALA A N     
942  C CA    . ALA A 118 ? 0.31478 0.31497 0.36975 -0.01514 0.00339  -0.00433 116 ALA A CA    
943  C C     . ALA A 118 ? 0.29488 0.27634 0.33942 -0.01111 0.00511  -0.00634 116 ALA A C     
944  O O     . ALA A 118 ? 0.32047 0.29196 0.35585 -0.00738 0.00403  -0.00995 116 ALA A O     
945  C CB    . ALA A 118 ? 0.29456 0.30670 0.35708 -0.00727 0.00602  -0.00299 116 ALA A CB    
946  N N     . THR A 119 ? 0.29188 0.26994 0.33677 -0.01026 0.00794  -0.00380 117 THR A N     
947  C CA    . THR A 119 ? 0.30967 0.27189 0.34475 -0.00446 0.00919  -0.00508 117 THR A CA    
948  C C     . THR A 119 ? 0.31335 0.25355 0.33415 -0.00774 0.00560  -0.00769 117 THR A C     
949  O O     . THR A 119 ? 0.33565 0.26308 0.34540 0.00049  0.00559  -0.01126 117 THR A O     
950  C CB    . THR A 119 ? 0.27585 0.23937 0.31316 -0.00293 0.01216  -0.00127 117 THR A CB    
951  O OG1   . THR A 119 ? 0.29307 0.27252 0.33968 0.00092  0.01419  -0.00056 117 THR A OG1   
952  C CG2   . THR A 119 ? 0.30066 0.25010 0.32820 0.00463  0.01296  -0.00179 117 THR A CG2   
953  N N     . ALA A 120 ? 0.32395 0.25983 0.34377 -0.01964 0.00200  -0.00595 118 ALA A N     
954  C CA    . ALA A 120 ? 0.32408 0.23358 0.32716 -0.02515 -0.00354 -0.00893 118 ALA A CA    
955  C C     . ALA A 120 ? 0.37629 0.28114 0.37105 -0.02076 -0.00655 -0.01585 118 ALA A C     
956  O O     . ALA A 120 ? 0.39682 0.27937 0.37404 -0.01307 -0.00798 -0.02102 118 ALA A O     
957  C CB    . ALA A 120 ? 0.36729 0.27730 0.37301 -0.04257 -0.00797 -0.00433 118 ALA A CB    
958  N N     . ALA A 121 ? 0.34059 0.26655 0.34618 -0.02401 -0.00750 -0.01591 119 ALA A N     
959  C CA    . ALA A 121 ? 0.34818 0.27220 0.34528 -0.01945 -0.01004 -0.02164 119 ALA A CA    
960  C C     . ALA A 121 ? 0.36207 0.28737 0.35532 -0.00421 -0.00464 -0.02368 119 ALA A C     
961  O O     . ALA A 121 ? 0.39170 0.30668 0.37019 0.00291  -0.00568 -0.02907 119 ALA A O     
962  C CB    . ALA A 121 ? 0.34591 0.29445 0.35628 -0.02455 -0.01185 -0.01964 119 ALA A CB    
963  N N     . GLY A 122 ? 0.33886 0.27809 0.34440 0.00081  0.00087  -0.01930 120 GLY A N     
964  C CA    . GLY A 122 ? 0.34588 0.29137 0.35034 0.01269  0.00542  -0.01950 120 GLY A CA    
965  C C     . GLY A 122 ? 0.38593 0.31309 0.37517 0.02223  0.00634  -0.02262 120 GLY A C     
966  O O     . GLY A 122 ? 0.37856 0.30682 0.35894 0.03291  0.00829  -0.02551 120 GLY A O     
967  N N     . VAL A 123 ? 0.36360 0.27416 0.34841 0.01968  0.00510  -0.02152 121 VAL A N     
968  C CA    . VAL A 123 ? 0.36896 0.25697 0.33613 0.03030  0.00497  -0.02438 121 VAL A CA    
969  C C     . VAL A 123 ? 0.39295 0.25754 0.33857 0.03286  0.00037  -0.03197 121 VAL A C     
970  O O     . VAL A 123 ? 0.41345 0.27038 0.34438 0.04818  0.00200  -0.03648 121 VAL A O     
971  C CB    . VAL A 123 ? 0.39385 0.26538 0.35852 0.02534  0.00362  -0.02045 121 VAL A CB    
972  C CG1   . VAL A 123 ? 0.44145 0.28148 0.38297 0.03639  0.00164  -0.02373 121 VAL A CG1   
973  C CG2   . VAL A 123 ? 0.37821 0.27200 0.35988 0.02680  0.00825  -0.01429 121 VAL A CG2   
974  N N     . MET A 124 ? 0.39564 0.25020 0.33825 0.01848  -0.00577 -0.03364 122 MET A N     
975  C CA    . MET A 124 ? 0.45732 0.28720 0.37693 0.01935  -0.01190 -0.04181 122 MET A CA    
976  C C     . MET A 124 ? 0.45006 0.29584 0.36639 0.03093  -0.00888 -0.04615 122 MET A C     
977  O O     . MET A 124 ? 0.47275 0.30021 0.36628 0.04366  -0.00983 -0.05342 122 MET A O     
978  C CB    . MET A 124 ? 0.45647 0.27834 0.37595 -0.00078 -0.02019 -0.04184 122 MET A CB    
979  C CG    . MET A 124 ? 0.48994 0.29562 0.41009 -0.01479 -0.02380 -0.03643 122 MET A CG    
980  S SD    . MET A 124 ? 0.57139 0.32382 0.45765 -0.00746 -0.02879 -0.04138 122 MET A SD    
981  C CE    . MET A 124 ? 0.70882 0.43106 0.56950 -0.01716 -0.04093 -0.05113 122 MET A CE    
982  N N     . ALA A 125 ? 0.39648 0.27504 0.33320 0.02755  -0.00528 -0.04153 123 ALA A N     
983  C CA    . ALA A 125 ? 0.41807 0.31301 0.35161 0.03662  -0.00235 -0.04360 123 ALA A CA    
984  C C     . ALA A 125 ? 0.42520 0.33191 0.35784 0.05375  0.00533  -0.04222 123 ALA A C     
985  O O     . ALA A 125 ? 0.42048 0.32670 0.33733 0.06702  0.00739  -0.04685 123 ALA A O     
986  C CB    . ALA A 125 ? 0.41209 0.33504 0.36585 0.02771  -0.00153 -0.03778 123 ALA A CB    
987  N N     . PHE A 126 ? 0.38901 0.30945 0.33841 0.05404  0.00958  -0.03562 124 PHE A N     
988  C CA    . PHE A 126 ? 0.39615 0.33797 0.35020 0.06749  0.01643  -0.03220 124 PHE A CA    
989  C C     . PHE A 126 ? 0.43123 0.35613 0.36839 0.08386  0.01770  -0.03612 124 PHE A C     
990  O O     . PHE A 126 ? 0.48750 0.42592 0.41801 0.09989  0.02253  -0.03690 124 PHE A O     
991  C CB    . PHE A 126 ? 0.35051 0.31508 0.32834 0.06038  0.01905  -0.02372 124 PHE A CB    
992  C CG    . PHE A 126 ? 0.37553 0.35473 0.36739 0.04774  0.01785  -0.01977 124 PHE A CG    
993  C CD1   . PHE A 126 ? 0.41517 0.40458 0.40357 0.04800  0.01824  -0.01993 124 PHE A CD1   
994  C CD2   . PHE A 126 ? 0.34002 0.32163 0.34625 0.03727  0.01625  -0.01588 124 PHE A CD2   
995  C CE1   . PHE A 126 ? 0.33150 0.33144 0.33065 0.03793  0.01649  -0.01574 124 PHE A CE1   
996  C CE2   . PHE A 126 ? 0.35115 0.34319 0.36753 0.02855  0.01473  -0.01268 124 PHE A CE2   
997  C CZ    . PHE A 126 ? 0.37142 0.37175 0.38417 0.02895  0.01461  -0.01235 124 PHE A CZ    
998  N N     . ALA A 127 ? 0.45302 0.34920 0.38213 0.08104  0.01355  -0.03789 125 ALA A N     
999  C CA    . ALA A 127 ? 0.50983 0.38365 0.41975 0.09753  0.01361  -0.04133 125 ALA A CA    
1000 C C     . ALA A 127 ? 0.54279 0.38157 0.42176 0.10530  0.00884  -0.05157 125 ALA A C     
1001 O O     . ALA A 127 ? 0.55820 0.38881 0.41829 0.12658  0.01115  -0.05626 125 ALA A O     
1002 C CB    . ALA A 127 ? 0.50078 0.35623 0.41317 0.09079  0.01080  -0.03741 125 ALA A CB    
1003 N N     . TYR A 128 ? 0.53165 0.35045 0.40401 0.08914  0.00176  -0.05537 126 TYR A N     
1004 C CA    . TYR A 128 ? 0.55566 0.33467 0.39581 0.09293  -0.00540 -0.06575 126 TYR A CA    
1005 C C     . TYR A 128 ? 0.55443 0.34248 0.38741 0.09192  -0.00683 -0.07155 126 TYR A C     
1006 O O     . TYR A 128 ? 0.61454 0.36937 0.41797 0.09582  -0.01348 -0.08148 126 TYR A O     
1007 C CB    . TYR A 128 ? 0.61508 0.35811 0.44760 0.07361  -0.01497 -0.06586 126 TYR A CB    
1008 C CG    . TYR A 128 ? 0.59461 0.32528 0.43173 0.07199  -0.01448 -0.05909 126 TYR A CG    
1009 C CD1   . TYR A 128 ? 0.70935 0.41664 0.52700 0.09194  -0.01334 -0.06109 126 TYR A CD1   
1010 C CD2   . TYR A 128 ? 0.58626 0.32909 0.44561 0.05177  -0.01523 -0.05046 126 TYR A CD2   
1011 C CE1   . TYR A 128 ? 0.64648 0.34177 0.46684 0.09046  -0.01345 -0.05408 126 TYR A CE1   
1012 C CE2   . TYR A 128 ? 0.60841 0.34083 0.47027 0.05021  -0.01464 -0.04374 126 TYR A CE2   
1013 C CZ    . TYR A 128 ? 0.64716 0.35518 0.48946 0.06885  -0.01405 -0.04534 126 TYR A CZ    
1014 O OH    . TYR A 128 ? 0.69661 0.39434 0.54051 0.06724  -0.01386 -0.03773 126 TYR A OH    
1015 N N     . ASN A 129 ? 0.53154 0.36061 0.38789 0.08709  -0.00156 -0.06575 127 ASN A N     
1016 C CA    . ASN A 129 ? 0.53152 0.37067 0.38192 0.08461  -0.00328 -0.06957 127 ASN A CA    
1017 C C     . ASN A 129 ? 0.55918 0.36993 0.39665 0.06790  -0.01475 -0.07544 127 ASN A C     
1018 O O     . ASN A 129 ? 0.60204 0.39746 0.41597 0.07135  -0.01981 -0.08416 127 ASN A O     
1019 C CB    . ASN A 129 ? 0.60154 0.44210 0.42907 0.10754  0.00116  -0.07623 127 ASN A CB    
1020 C CG    . ASN A 129 ? 0.58681 0.45790 0.41893 0.10701  0.00425  -0.07450 127 ASN A CG    
1021 O OD1   . ASN A 129 ? 0.56293 0.45562 0.41728 0.09108  0.00371  -0.06734 127 ASN A OD1   
1022 N ND2   . ASN A 129 ? 0.74226 0.61329 0.55055 0.12563  0.00720  -0.08121 127 ASN A ND2   
1023 N N     . ARG A 130 ? 0.52083 0.32686 0.37355 0.04928  -0.01911 -0.07029 128 ARG A N     
1024 C CA    . ARG A 130 ? 0.56159 0.34813 0.40742 0.02994  -0.03025 -0.07326 128 ARG A CA    
1025 C C     . ARG A 130 ? 0.49140 0.31259 0.36535 0.01420  -0.03043 -0.06572 128 ARG A C     
1026 O O     . ARG A 130 ? 0.45424 0.30291 0.35376 0.01363  -0.02338 -0.05712 128 ARG A O     
1027 C CB    . ARG A 130 ? 0.62711 0.38085 0.46606 0.01987  -0.03593 -0.07223 128 ARG A CB    
1028 C CG    . ARG A 130 ? 0.58057 0.28867 0.38424 0.03456  -0.03923 -0.08111 128 ARG A CG    
1029 C CD    . ARG A 130 ? 0.69364 0.37816 0.46605 0.03956  -0.04669 -0.09343 128 ARG A CD    
1030 N N     . PRO A 131 ? 0.51742 0.33776 0.38571 0.00269  -0.03887 -0.06905 129 PRO A N     
1031 C CA    . PRO A 131 ? 0.47211 0.32731 0.36504 -0.00801 -0.03902 -0.06210 129 PRO A CA    
1032 C C     . PRO A 131 ? 0.49465 0.35901 0.40917 -0.02497 -0.04124 -0.05438 129 PRO A C     
1033 O O     . PRO A 131 ? 0.53402 0.37565 0.44242 -0.03374 -0.04524 -0.05440 129 PRO A O     
1034 C CB    . PRO A 131 ? 0.50146 0.35022 0.37698 -0.01349 -0.04872 -0.06904 129 PRO A CB    
1035 C CG    . PRO A 131 ? 0.57725 0.38160 0.42317 -0.01670 -0.05750 -0.07832 129 PRO A CG    
1036 C CD    . PRO A 131 ? 0.54576 0.33231 0.38207 0.00075  -0.04937 -0.07997 129 PRO A CD    
1037 N N     . GLY A 132 ? 0.42829 0.32653 0.36693 -0.02874 -0.03853 -0.04719 130 GLY A N     
1038 C CA    . GLY A 132 ? 0.46632 0.38123 0.42710 -0.04110 -0.03870 -0.03926 130 GLY A CA    
1039 C C     . GLY A 132 ? 0.46458 0.41421 0.44741 -0.03737 -0.03404 -0.03277 130 GLY A C     
1040 O O     . GLY A 132 ? 0.44800 0.40683 0.42865 -0.02786 -0.03169 -0.03360 130 GLY A O     
1041 N N     . VAL A 133 ? 0.35837 0.32637 0.36078 -0.04462 -0.03290 -0.02587 131 VAL A N     
1042 C CA    . VAL A 133 ? 0.34424 0.34187 0.36577 -0.04015 -0.02938 -0.01989 131 VAL A CA    
1043 C C     . VAL A 133 ? 0.35249 0.35156 0.38257 -0.03117 -0.02039 -0.01652 131 VAL A C     
1044 O O     . VAL A 133 ? 0.34592 0.34613 0.38351 -0.03506 -0.01792 -0.01327 131 VAL A O     
1045 C CB    . VAL A 133 ? 0.37560 0.39670 0.41210 -0.05150 -0.03420 -0.01479 131 VAL A CB    
1046 C CG1   . VAL A 133 ? 0.38541 0.43417 0.43843 -0.04272 -0.03060 -0.00935 131 VAL A CG1   
1047 C CG2   . VAL A 133 ? 0.36743 0.38695 0.39472 -0.06290 -0.04491 -0.01819 131 VAL A CG2   
1048 N N     . TYR A 134 ? 0.33945 0.33921 0.36762 -0.02011 -0.01594 -0.01674 132 TYR A N     
1049 C CA    . TYR A 134 ? 0.30119 0.30229 0.33601 -0.01260 -0.00900 -0.01381 132 TYR A CA    
1050 C C     . TYR A 134 ? 0.31229 0.33027 0.35783 -0.00831 -0.00807 -0.00928 132 TYR A C     
1051 O O     . TYR A 134 ? 0.32513 0.34589 0.36676 -0.00411 -0.00873 -0.00854 132 TYR A O     
1052 C CB    . TYR A 134 ? 0.28602 0.27523 0.30960 -0.00478 -0.00549 -0.01656 132 TYR A CB    
1053 C CG    . TYR A 134 ? 0.31667 0.30911 0.34667 0.00129  0.00030  -0.01328 132 TYR A CG    
1054 C CD1   . TYR A 134 ? 0.30111 0.28844 0.33485 0.00077  0.00267  -0.01240 132 TYR A CD1   
1055 C CD2   . TYR A 134 ? 0.27323 0.27397 0.30460 0.00626  0.00266  -0.01036 132 TYR A CD2   
1056 C CE1   . TYR A 134 ? 0.32145 0.31244 0.36010 0.00556  0.00662  -0.00976 132 TYR A CE1   
1057 C CE2   . TYR A 134 ? 0.30081 0.30484 0.33764 0.00925  0.00638  -0.00707 132 TYR A CE2   
1058 C CZ    . TYR A 134 ? 0.32171 0.32108 0.36220 0.00909  0.00801  -0.00732 132 TYR A CZ    
1059 O OH    . TYR A 134 ? 0.32761 0.33094 0.37280 0.01126  0.01041  -0.00438 132 TYR A OH    
1060 N N     . LEU A 135 ? 0.27756 0.30584 0.33457 -0.00874 -0.00682 -0.00601 133 LEU A N     
1061 C CA    . LEU A 135 ? 0.25524 0.29650 0.31993 -0.00288 -0.00696 -0.00237 133 LEU A CA    
1062 C C     . LEU A 135 ? 0.26189 0.30037 0.33060 0.00247  -0.00247 -0.00090 133 LEU A C     
1063 O O     . LEU A 135 ? 0.30511 0.35095 0.38010 0.00189  -0.00071 0.00006  133 LEU A O     
1064 C CB    . LEU A 135 ? 0.25791 0.31844 0.33106 -0.00615 -0.01077 -0.00037 133 LEU A CB    
1065 C CG    . LEU A 135 ? 0.28374 0.35928 0.36381 0.00296  -0.01144 0.00333  133 LEU A CG    
1066 C CD1   . LEU A 135 ? 0.27276 0.33955 0.34506 0.00962  -0.01309 0.00435  133 LEU A CD1   
1067 C CD2   . LEU A 135 ? 0.31227 0.41308 0.40183 -0.00055 -0.01567 0.00581  133 LEU A CD2   
1068 N N     . GLU A 136 ? 0.25798 0.28681 0.32224 0.00674  -0.00098 -0.00037 134 GLU A N     
1069 C CA    . GLU A 136 ? 0.28647 0.30995 0.35172 0.01126  0.00118  0.00061  134 GLU A CA    
1070 C C     . GLU A 136 ? 0.26400 0.28338 0.32607 0.01623  -0.00145 0.00334  134 GLU A C     
1071 O O     . GLU A 136 ? 0.27889 0.30326 0.34003 0.01755  -0.00435 0.00507  134 GLU A O     
1072 C CB    . GLU A 136 ? 0.30563 0.32019 0.36790 0.00921  0.00402  -0.00053 134 GLU A CB    
1073 C CG    . GLU A 136 ? 0.28969 0.30153 0.34664 0.00770  0.00405  -0.00033 134 GLU A CG    
1074 C CD    . GLU A 136 ? 0.32103 0.33232 0.37568 0.00873  0.00237  0.00344  134 GLU A CD    
1075 O OE1   . GLU A 136 ? 0.33888 0.34535 0.39335 0.00857  0.00202  0.00598  134 GLU A OE1   
1076 O OE2   . GLU A 136 ? 0.35184 0.36680 0.40434 0.00907  0.00010  0.00435  134 GLU A OE2   
1077 N N     . THR A 137 ? 0.22917 0.23761 0.28795 0.01864  -0.00144 0.00401  135 THR A N     
1078 C CA    . THR A 137 ? 0.28327 0.28216 0.33636 0.02369  -0.00515 0.00663  135 THR A CA    
1079 C C     . THR A 137 ? 0.29132 0.28707 0.33976 0.02016  -0.00747 0.01111  135 THR A C     
1080 O O     . THR A 137 ? 0.26457 0.25694 0.30874 0.02468  -0.01101 0.01417  135 THR A O     
1081 C CB    . THR A 137 ? 0.28221 0.26543 0.32958 0.02503  -0.00624 0.00576  135 THR A CB    
1082 O OG1   . THR A 137 ? 0.29083 0.25920 0.32930 0.03126  -0.01095 0.00759  135 THR A OG1   
1083 C CG2   . THR A 137 ? 0.26063 0.23916 0.30703 0.01597  -0.00588 0.00757  135 THR A CG2   
1084 N N     . ASN A 138 ? 0.25507 0.25336 0.30345 0.01345  -0.00527 0.01211  136 ASN A N     
1085 C CA    . ASN A 138 ? 0.25174 0.25083 0.29509 0.01027  -0.00633 0.01729  136 ASN A CA    
1086 C C     . ASN A 138 ? 0.27639 0.28550 0.31866 0.01231  -0.00718 0.01663  136 ASN A C     
1087 O O     . ASN A 138 ? 0.28248 0.29049 0.31929 0.01360  -0.01013 0.02134  136 ASN A O     
1088 C CB    . ASN A 138 ? 0.26504 0.26912 0.30894 0.00472  -0.00289 0.01870  136 ASN A CB    
1089 C CG    . ASN A 138 ? 0.31804 0.31412 0.36265 0.00069  -0.00394 0.02083  136 ASN A CG    
1090 O OD1   . ASN A 138 ? 0.32632 0.31122 0.36590 -0.00258 -0.00799 0.02602  136 ASN A OD1   
1091 N ND2   . ASN A 138 ? 0.29266 0.29174 0.34186 0.00064  -0.00146 0.01686  136 ASN A ND2   
1092 N N     . VAL A 139 ? 0.25899 0.27630 0.30473 0.01172  -0.00551 0.01123  137 VAL A N     
1093 C CA    . VAL A 139 ? 0.27731 0.30328 0.32110 0.01194  -0.00811 0.00969  137 VAL A CA    
1094 C C     . VAL A 139 ? 0.31160 0.34256 0.35855 0.01678  -0.01230 0.01182  137 VAL A C     
1095 O O     . VAL A 139 ? 0.28644 0.32245 0.32919 0.01868  -0.01598 0.01455  137 VAL A O     
1096 C CB    . VAL A 139 ? 0.24770 0.27662 0.29305 0.00835  -0.00719 0.00355  137 VAL A CB    
1097 C CG1   . VAL A 139 ? 0.26690 0.30424 0.31004 0.00630  -0.01208 0.00166  137 VAL A CG1   
1098 C CG2   . VAL A 139 ? 0.27774 0.30085 0.31698 0.00727  -0.00336 0.00119  137 VAL A CG2   
1099 N N     . ARG A 140 ? 0.24709 0.27859 0.30069 0.02038  -0.01169 0.01075  138 ARG A N     
1100 C CA    . ARG A 140 ? 0.24202 0.28085 0.29854 0.02850  -0.01489 0.01276  138 ARG A CA    
1101 C C     . ARG A 140 ? 0.29041 0.31751 0.33779 0.03416  -0.01836 0.01815  138 ARG A C     
1102 O O     . ARG A 140 ? 0.27770 0.31255 0.32358 0.03952  -0.02245 0.02114  138 ARG A O     
1103 C CB    . ARG A 140 ? 0.25355 0.29271 0.31535 0.03374  -0.01235 0.01073  138 ARG A CB    
1104 C CG    . ARG A 140 ? 0.23406 0.28585 0.29933 0.04505  -0.01463 0.01238  138 ARG A CG    
1105 C CD    . ARG A 140 ? 0.31372 0.36780 0.38211 0.05230  -0.01112 0.01002  138 ARG A CD    
1106 N NE    . ARG A 140 ? 0.27537 0.34547 0.35368 0.04401  -0.00727 0.00812  138 ARG A NE    
1107 C CZ    . ARG A 140 ? 0.29202 0.35264 0.36939 0.03804  -0.00352 0.00561  138 ARG A CZ    
1108 N NH1   . ARG A 140 ? 0.27907 0.31740 0.34771 0.03885  -0.00310 0.00420  138 ARG A NH1   
1109 N NH2   . ARG A 140 ? 0.28206 0.35592 0.36699 0.03021  -0.00087 0.00527  138 ARG A NH2   
1110 N N     . THR A 141 ? 0.27527 0.28365 0.31583 0.03181  -0.01746 0.02032  139 THR A N     
1111 C CA    . THR A 141 ? 0.27705 0.26965 0.30681 0.03427  -0.02139 0.02692  139 THR A CA    
1112 C C     . THR A 141 ? 0.30642 0.30691 0.33154 0.03140  -0.02305 0.03150  139 THR A C     
1113 O O     . THR A 141 ? 0.30457 0.30150 0.32299 0.03753  -0.02758 0.03662  139 THR A O     
1114 C CB    . THR A 141 ? 0.33438 0.30787 0.35870 0.02767  -0.02077 0.02910  139 THR A CB    
1115 O OG1   . THR A 141 ? 0.33404 0.28931 0.35317 0.03470  -0.02357 0.02755  139 THR A OG1   
1116 C CG2   . THR A 141 ? 0.31800 0.28244 0.33287 0.02146  -0.02308 0.03788  139 THR A CG2   
1117 N N     . VAL A 142 ? 0.28575 0.29654 0.31244 0.02385  -0.01965 0.02949  140 VAL A N     
1118 C CA    . VAL A 142 ? 0.30076 0.31905 0.32006 0.02214  -0.02092 0.03311  140 VAL A CA    
1119 C C     . VAL A 142 ? 0.28387 0.31478 0.30423 0.02778  -0.02573 0.03185  140 VAL A C     
1120 O O     . VAL A 142 ? 0.30815 0.33964 0.32068 0.03142  -0.02978 0.03769  140 VAL A O     
1121 C CB    . VAL A 142 ? 0.26082 0.28718 0.27912 0.01612  -0.01623 0.02934  140 VAL A CB    
1122 C CG1   . VAL A 142 ? 0.29401 0.32947 0.30198 0.01641  -0.01776 0.03134  140 VAL A CG1   
1123 C CG2   . VAL A 142 ? 0.28329 0.30366 0.30137 0.01095  -0.01172 0.03280  140 VAL A CG2   
1124 N N     . PHE A 143 ? 0.28275 0.32554 0.31283 0.02771  -0.02580 0.02520  141 PHE A N     
1125 C CA    . PHE A 143 ? 0.26559 0.32607 0.29892 0.03047  -0.03109 0.02437  141 PHE A CA    
1126 C C     . PHE A 143 ? 0.30098 0.36344 0.33559 0.04190  -0.03506 0.02960  141 PHE A C     
1127 O O     . PHE A 143 ? 0.30251 0.37618 0.33431 0.04655  -0.04054 0.03305  141 PHE A O     
1128 C CB    . PHE A 143 ? 0.27895 0.35202 0.32281 0.02469  -0.03045 0.01758  141 PHE A CB    
1129 C CG    . PHE A 143 ? 0.26882 0.34037 0.30645 0.01549  -0.03019 0.01211  141 PHE A CG    
1130 C CD1   . PHE A 143 ? 0.28484 0.34260 0.31799 0.01222  -0.02454 0.00930  141 PHE A CD1   
1131 C CD2   . PHE A 143 ? 0.29109 0.37435 0.32548 0.01122  -0.03636 0.00961  141 PHE A CD2   
1132 C CE1   . PHE A 143 ? 0.28765 0.34145 0.31197 0.00729  -0.02439 0.00369  141 PHE A CE1   
1133 C CE2   . PHE A 143 ? 0.28561 0.36189 0.30938 0.00429  -0.03718 0.00331  141 PHE A CE2   
1134 C CZ    . PHE A 143 ? 0.27257 0.33305 0.29057 0.00355  -0.03082 0.00012  141 PHE A CZ    
1135 N N     . LEU A 144 ? 0.31180 0.36256 0.34866 0.04803  -0.03289 0.03000  142 LEU A N     
1136 C CA    . LEU A 144 ? 0.30767 0.35477 0.34144 0.06218  -0.03672 0.03437  142 LEU A CA    
1137 C C     . LEU A 144 ? 0.33067 0.35989 0.34922 0.06516  -0.04073 0.04226  142 LEU A C     
1138 O O     . LEU A 144 ? 0.34240 0.37599 0.35658 0.07594  -0.04606 0.04704  142 LEU A O     
1139 C CB    . LEU A 144 ? 0.30227 0.33462 0.33651 0.06855  -0.03384 0.03189  142 LEU A CB    
1140 C CG    . LEU A 144 ? 0.32058 0.37359 0.36903 0.06990  -0.03014 0.02620  142 LEU A CG    
1141 C CD1   . LEU A 144 ? 0.33075 0.36518 0.37519 0.07616  -0.02718 0.02339  142 LEU A CD1   
1142 C CD2   . LEU A 144 ? 0.32938 0.41273 0.38734 0.07949  -0.03307 0.02770  142 LEU A CD2   
1143 N N     . HIS A 145 ? 0.32979 0.34012 0.34014 0.05580  -0.03832 0.04481  143 HIS A N     
1144 C CA    . HIS A 145 ? 0.35371 0.34631 0.34902 0.05577  -0.04171 0.05425  143 HIS A CA    
1145 C C     . HIS A 145 ? 0.36816 0.37761 0.35925 0.05482  -0.04432 0.05787  143 HIS A C     
1146 O O     . HIS A 145 ? 0.42683 0.43044 0.40749 0.06213  -0.04965 0.06562  143 HIS A O     
1147 C CB    . HIS A 145 ? 0.34974 0.32573 0.34011 0.04340  -0.03803 0.05713  143 HIS A CB    
1148 C CG    . HIS A 145 ? 0.42130 0.37740 0.39613 0.04064  -0.04158 0.06876  143 HIS A CG    
1149 N ND1   . HIS A 145 ? 0.45095 0.37849 0.41392 0.04760  -0.04739 0.07417  143 HIS A ND1   
1150 C CD2   . HIS A 145 ? 0.40598 0.36615 0.37337 0.03206  -0.04041 0.07674  143 HIS A CD2   
1151 C CE1   . HIS A 145 ? 0.48976 0.40257 0.43893 0.04130  -0.05018 0.08583  143 HIS A CE1   
1152 N NE2   . HIS A 145 ? 0.46664 0.40157 0.41917 0.03174  -0.04550 0.08804  143 HIS A NE2   
1153 N N     . GLU A 146 ? 0.35091 0.37898 0.34753 0.04664  -0.04130 0.05217  144 GLU A N     
1154 C CA    . GLU A 146 ? 0.33516 0.37619 0.32374 0.04440  -0.04365 0.05444  144 GLU A CA    
1155 C C     . GLU A 146 ? 0.39318 0.45536 0.38618 0.05079  -0.05010 0.05215  144 GLU A C     
1156 O O     . GLU A 146 ? 0.41276 0.48070 0.39611 0.05476  -0.05526 0.05779  144 GLU A O     
1157 C CB    . GLU A 146 ? 0.36623 0.41418 0.35468 0.03446  -0.03831 0.04823  144 GLU A CB    
1158 C CG    . GLU A 146 ? 0.37286 0.40947 0.35526 0.02801  -0.03229 0.05299  144 GLU A CG    
1159 C CD    . GLU A 146 ? 0.50912 0.53893 0.47758 0.02815  -0.03402 0.06541  144 GLU A CD    
1160 O OE1   . GLU A 146 ? 0.48764 0.52604 0.44744 0.03244  -0.03848 0.06826  144 GLU A OE1   
1161 O OE2   . GLU A 146 ? 0.48529 0.50183 0.45085 0.02274  -0.03140 0.07297  144 GLU A OE2   
1162 N N     . LEU A 147 ? 0.32431 0.40070 0.33188 0.05095  -0.05022 0.04486  145 LEU A N     
1163 C CA    . LEU A 147 ? 0.33178 0.43438 0.34623 0.05300  -0.05658 0.04272  145 LEU A CA    
1164 C C     . LEU A 147 ? 0.36206 0.47649 0.38652 0.06598  -0.05974 0.04568  145 LEU A C     
1165 O O     . LEU A 147 ? 0.36262 0.50295 0.39296 0.06969  -0.06608 0.04673  145 LEU A O     
1166 C CB    . LEU A 147 ? 0.31049 0.42514 0.33347 0.04098  -0.05542 0.03332  145 LEU A CB    
1167 C CG    . LEU A 147 ? 0.32993 0.43118 0.34113 0.03164  -0.05161 0.02906  145 LEU A CG    
1168 C CD1   . LEU A 147 ? 0.35222 0.45943 0.36816 0.02120  -0.05207 0.01971  145 LEU A CD1   
1169 C CD2   . LEU A 147 ? 0.36926 0.47175 0.36365 0.03306  -0.05562 0.03296  145 LEU A CD2   
1170 N N     . PHE A 148 ? 0.33978 0.43730 0.36541 0.07370  -0.05589 0.04689  146 PHE A N     
1171 C CA    . PHE A 148 ? 0.34515 0.45247 0.37764 0.08957  -0.05789 0.04882  146 PHE A CA    
1172 C C     . PHE A 148 ? 0.41607 0.49209 0.43338 0.10279  -0.05905 0.05496  146 PHE A C     
1173 O O     . PHE A 148 ? 0.40148 0.46837 0.41925 0.11500  -0.05769 0.05389  146 PHE A O     
1174 C CB    . PHE A 148 ? 0.32423 0.44303 0.37200 0.08764  -0.05254 0.04238  146 PHE A CB    
1175 C CG    . PHE A 148 ? 0.34193 0.49029 0.40368 0.07440  -0.05312 0.03788  146 PHE A CG    
1176 C CD1   . PHE A 148 ? 0.31429 0.45353 0.37463 0.05774  -0.05007 0.03253  146 PHE A CD1   
1177 C CD2   . PHE A 148 ? 0.38645 0.57169 0.46165 0.07855  -0.05759 0.03958  146 PHE A CD2   
1178 C CE1   . PHE A 148 ? 0.30409 0.46423 0.37352 0.04480  -0.05225 0.02835  146 PHE A CE1   
1179 C CE2   . PHE A 148 ? 0.36105 0.57140 0.44788 0.06318  -0.05978 0.03632  146 PHE A CE2   
1180 C CZ    . PHE A 148 ? 0.32472 0.51915 0.40717 0.04597  -0.05751 0.03044  146 PHE A CZ    
1181 N N     . ALA A 149 ? 0.42510 0.48408 0.42672 0.10115  -0.06236 0.06193  147 ALA A N     
1182 C CA    . ALA A 149 ? 0.45533 0.47643 0.43925 0.10741  -0.06376 0.06874  147 ALA A CA    
1183 C C     . ALA A 149 ? 0.52242 0.53509 0.50144 0.12962  -0.06803 0.07109  147 ALA A C     
1184 O O     . ALA A 149 ? 0.63002 0.60880 0.59761 0.13545  -0.06793 0.07150  147 ALA A O     
1185 C CB    . ALA A 149 ? 0.52439 0.53541 0.49276 0.10193  -0.06714 0.07798  147 ALA A CB    
1186 N N     . ASP A 150 ? 0.51238 0.55510 0.49852 0.14299  -0.07241 0.07252  148 ASP A N     
1187 C CA    . ASP A 150 ? 0.59450 0.63118 0.57380 0.16807  -0.07675 0.07574  148 ASP A CA    
1188 C C     . ASP A 150 ? 0.55448 0.61615 0.54998 0.17977  -0.07284 0.06849  148 ASP A C     
1189 O O     . ASP A 150 ? 0.61018 0.67543 0.60191 0.20382  -0.07571 0.07036  148 ASP A O     
1190 C CB    . ASP A 150 ? 0.60398 0.66009 0.57950 0.17949  -0.08463 0.08386  148 ASP A CB    
1191 N N     . ARG A 151 ? 0.43543 0.51438 0.44744 0.16477  -0.06619 0.06091  149 ARG A N     
1192 C CA    . ARG A 151 ? 0.46801 0.57878 0.49740 0.17316  -0.06196 0.05567  149 ARG A CA    
1193 C C     . ARG A 151 ? 0.47096 0.55211 0.49152 0.18201  -0.05722 0.05051  149 ARG A C     
1194 O O     . ARG A 151 ? 0.49596 0.54483 0.50840 0.16828  -0.05444 0.04746  149 ARG A O     
1195 C CB    . ARG A 151 ? 0.40917 0.55368 0.45949 0.15174  -0.05816 0.05119  149 ARG A CB    
1196 C CG    . ARG A 151 ? 0.42379 0.60758 0.48522 0.14663  -0.06418 0.05487  149 ARG A CG    
1197 C CD    . ARG A 151 ? 0.40225 0.63176 0.47960 0.16302  -0.06600 0.05751  149 ARG A CD    
1198 N NE    . ARG A 151 ? 0.43339 0.68553 0.52745 0.15946  -0.05894 0.05303  149 ARG A NE    
1199 C CZ    . ARG A 151 ? 0.37540 0.65191 0.48546 0.13771  -0.05725 0.05035  149 ARG A CZ    
1200 N NH1   . ARG A 151 ? 0.39515 0.67591 0.50593 0.11849  -0.06249 0.05016  149 ARG A NH1   
1201 N NH2   . ARG A 151 ? 0.37695 0.67156 0.50016 0.13541  -0.05050 0.04784  149 ARG A NH2   
1202 N N     . GLU A 152 ? 0.52297 0.61838 0.54516 0.20547  -0.05640 0.04938  150 GLU A N     
1203 C CA    . GLU A 152 ? 0.50827 0.57438 0.51786 0.21805  -0.05287 0.04363  150 GLU A CA    
1204 C C     . GLU A 152 ? 0.49382 0.57463 0.51795 0.20323  -0.04463 0.03671  150 GLU A C     
1205 O O     . GLU A 152 ? 0.53742 0.58355 0.55003 0.19808  -0.04221 0.03164  150 GLU A O     
1206 C CB    . GLU A 152 ? 0.55597 0.63369 0.56100 0.24318  -0.05226 0.04281  150 GLU A CB    
1207 C CG    . GLU A 152 ? 0.62665 0.68421 0.61449 0.25518  -0.05924 0.04849  150 GLU A CG    
1208 C CD    . GLU A 152 ? 0.80346 0.82283 0.76652 0.27341  -0.05928 0.04428  150 GLU A CD    
1209 O OE1   . GLU A 152 ? 0.89995 0.92188 0.86203 0.28006  -0.05315 0.03671  150 GLU A OE1   
1210 O OE2   . GLU A 152 ? 0.89878 0.88619 0.84213 0.28116  -0.06570 0.04870  150 GLU A OE2   
1211 N N     . LYS A 153 ? 0.48196 0.61394 0.53057 0.19603  -0.04100 0.03702  151 LYS A N     
1212 C CA    . LYS A 153 ? 0.42098 0.56979 0.48371 0.18177  -0.03345 0.03210  151 LYS A CA    
1213 C C     . LYS A 153 ? 0.44320 0.62928 0.52691 0.15992  -0.03374 0.03454  151 LYS A C     
1214 O O     . LYS A 153 ? 0.41911 0.64213 0.51449 0.16388  -0.03765 0.03946  151 LYS A O     
1215 C CB    . LYS A 153 ? 0.48738 0.66167 0.55559 0.20152  -0.02774 0.02988  151 LYS A CB    
1216 C CG    . LYS A 153 ? 0.61855 0.75182 0.66210 0.22360  -0.02748 0.02506  151 LYS A CG    
1217 C CD    . LYS A 153 ? 0.65261 0.73302 0.67946 0.20905  -0.02802 0.02011  151 LYS A CD    
1218 C CE    . LYS A 153 ? 0.66516 0.72107 0.67571 0.22363  -0.02471 0.01267  151 LYS A CE    
1219 N NZ    . LYS A 153 ? 0.59002 0.63543 0.60332 0.20341  -0.02003 0.00780  151 LYS A NZ    
1220 N N     . VAL A 154 ? 0.38338 0.55857 0.47033 0.13750  -0.03047 0.03098  152 VAL A N     
1221 C CA    . VAL A 154 ? 0.32208 0.51945 0.42261 0.11515  -0.03178 0.03175  152 VAL A CA    
1222 C C     . VAL A 154 ? 0.30437 0.50575 0.41331 0.10098  -0.02521 0.02792  152 VAL A C     
1223 O O     . VAL A 154 ? 0.31990 0.48977 0.41897 0.09828  -0.02137 0.02379  152 VAL A O     
1224 C CB    . VAL A 154 ? 0.32138 0.49133 0.41045 0.10248  -0.03616 0.03180  152 VAL A CB    
1225 C CG1   . VAL A 154 ? 0.35417 0.54457 0.45327 0.08207  -0.03863 0.03120  152 VAL A CG1   
1226 C CG2   . VAL A 154 ? 0.34103 0.50042 0.41795 0.11700  -0.04244 0.03676  152 VAL A CG2   
1227 N N     . SER A 155 ? 0.29175 0.53174 0.41835 0.09107  -0.02456 0.03009  153 SER A N     
1228 C CA    . SER A 155 ? 0.28660 0.52945 0.41992 0.07697  -0.01877 0.02796  153 SER A CA    
1229 C C     . SER A 155 ? 0.32449 0.54697 0.45396 0.05464  -0.02102 0.02504  153 SER A C     
1230 O O     . SER A 155 ? 0.30724 0.52687 0.43339 0.04776  -0.02735 0.02528  153 SER A O     
1231 C CB    . SER A 155 ? 0.32451 0.61715 0.47767 0.07405  -0.01706 0.03312  153 SER A CB    
1232 O OG    . SER A 155 ? 0.35189 0.66661 0.51483 0.05713  -0.02412 0.03623  153 SER A OG    
1233 N N     . ASP A 156 ? 0.28532 0.49331 0.41345 0.04497  -0.01583 0.02212  154 ASP A N     
1234 C CA    . ASP A 156 ? 0.27129 0.46091 0.39497 0.02599  -0.01745 0.01914  154 ASP A CA    
1235 C C     . ASP A 156 ? 0.23698 0.45064 0.36973 0.01027  -0.02345 0.02151  154 ASP A C     
1236 O O     . ASP A 156 ? 0.25179 0.44906 0.37661 -0.00206 -0.02801 0.01836  154 ASP A O     
1237 C CB    . ASP A 156 ? 0.22958 0.40442 0.35140 0.02022  -0.01108 0.01689  154 ASP A CB    
1238 C CG    . ASP A 156 ? 0.34306 0.48532 0.45213 0.02894  -0.00772 0.01307  154 ASP A CG    
1239 O OD1   . ASP A 156 ? 0.28733 0.41711 0.38875 0.03887  -0.01006 0.01277  154 ASP A OD1   
1240 O OD2   . ASP A 156 ? 0.34980 0.47892 0.45605 0.02497  -0.00335 0.01108  154 ASP A OD2   
1241 N N     . ARG A 157 ? 0.25781 0.51080 0.40622 0.01022  -0.02383 0.02705  155 ARG A N     
1242 C CA    . ARG A 157 ? 0.22296 0.50261 0.38107 -0.00642 -0.03134 0.03043  155 ARG A CA    
1243 C C     . ARG A 157 ? 0.27822 0.55340 0.42911 -0.00617 -0.04006 0.02868  155 ARG A C     
1244 O O     . ARG A 157 ? 0.29164 0.56385 0.43901 -0.02331 -0.04755 0.02692  155 ARG A O     
1245 C CB    . ARG A 157 ? 0.23813 0.56878 0.41624 -0.00239 -0.03003 0.03842  155 ARG A CB    
1246 C CG    . ARG A 157 ? 0.33582 0.69985 0.52689 -0.02288 -0.03812 0.04367  155 ARG A CG    
1247 C CD    . ARG A 157 ? 0.37055 0.78317 0.58226 -0.02536 -0.03358 0.05282  155 ARG A CD    
1248 N NE    . ARG A 157 ? 0.40372 0.81223 0.61753 -0.05184 -0.03461 0.05537  155 ARG A NE    
1249 C CZ    . ARG A 157 ? 0.33585 0.75441 0.55359 -0.07654 -0.04494 0.05807  155 ARG A CZ    
1250 N NH1   . ARG A 157 ? 0.36513 0.80464 0.58738 -0.07826 -0.05484 0.05882  155 ARG A NH1   
1251 N NH2   . ARG A 157 ? 0.48499 0.89041 0.70033 -0.10036 -0.04627 0.06023  155 ARG A NH2   
1252 N N     . GLU A 158 ? 0.26439 0.53776 0.41095 0.01334  -0.03989 0.02932  156 GLU A N     
1253 C CA    . GLU A 158 ? 0.26090 0.53141 0.39952 0.01481  -0.04794 0.02900  156 GLU A CA    
1254 C C     . GLU A 158 ? 0.28011 0.50903 0.39969 0.00879  -0.04822 0.02289  156 GLU A C     
1255 O O     . GLU A 158 ? 0.28995 0.51559 0.40115 0.00195  -0.05543 0.02122  156 GLU A O     
1256 C CB    . GLU A 158 ? 0.36413 0.64333 0.50214 0.03808  -0.04801 0.03293  156 GLU A CB    
1257 C CG    . GLU A 158 ? 0.42754 0.74619 0.58234 0.05044  -0.04514 0.03836  156 GLU A CG    
1258 C CD    . GLU A 158 ? 0.44020 0.76239 0.59056 0.07648  -0.04596 0.04160  156 GLU A CD    
1259 O OE1   . GLU A 158 ? 0.45615 0.77986 0.60093 0.07997  -0.05351 0.04378  156 GLU A OE1   
1260 O OE2   . GLU A 158 ? 0.46821 0.78828 0.61795 0.09400  -0.03941 0.04169  156 GLU A OE2   
1261 N N     . LEU A 159 ? 0.28339 0.48297 0.39555 0.01204  -0.04060 0.01973  157 LEU A N     
1262 C CA    . LEU A 159 ? 0.26355 0.42903 0.35933 0.00786  -0.03971 0.01496  157 LEU A CA    
1263 C C     . LEU A 159 ? 0.28220 0.43815 0.37357 -0.00956 -0.04177 0.01007  157 LEU A C     
1264 O O     . LEU A 159 ? 0.32130 0.45924 0.39843 -0.01365 -0.04454 0.00598  157 LEU A O     
1265 C CB    . LEU A 159 ? 0.26658 0.40741 0.35698 0.01629  -0.03188 0.01395  157 LEU A CB    
1266 C CG    . LEU A 159 ? 0.26183 0.40047 0.35138 0.03346  -0.03012 0.01760  157 LEU A CG    
1267 C CD1   . LEU A 159 ? 0.28773 0.39893 0.37029 0.03685  -0.02399 0.01559  157 LEU A CD1   
1268 C CD2   . LEU A 159 ? 0.30906 0.44443 0.38955 0.03990  -0.03556 0.02085  157 LEU A CD2   
1269 N N     . TRP A 160 ? 0.29617 0.46203 0.39739 -0.01912 -0.04036 0.01066  158 TRP A N     
1270 C CA    . TRP A 160 ? 0.32317 0.47161 0.41705 -0.03504 -0.04220 0.00628  158 TRP A CA    
1271 C C     . TRP A 160 ? 0.31515 0.45669 0.39669 -0.04505 -0.05166 0.00201  158 TRP A C     
1272 O O     . TRP A 160 ? 0.32085 0.43280 0.38549 -0.04807 -0.05169 -0.00428 158 TRP A O     
1273 C CB    . TRP A 160 ? 0.35149 0.51885 0.45908 -0.04646 -0.04176 0.01040  158 TRP A CB    
1274 C CG    . TRP A 160 ? 0.36517 0.50658 0.46333 -0.06004 -0.04166 0.00701  158 TRP A CG    
1275 C CD1   . TRP A 160 ? 0.45628 0.58939 0.54724 -0.07821 -0.05012 0.00504  158 TRP A CD1   
1276 C CD2   . TRP A 160 ? 0.42350 0.54463 0.51820 -0.05706 -0.03369 0.00613  158 TRP A CD2   
1277 N NE1   . TRP A 160 ? 0.43268 0.53669 0.51346 -0.08506 -0.04771 0.00262  158 TRP A NE1   
1278 C CE2   . TRP A 160 ? 0.41379 0.51263 0.49792 -0.07207 -0.03741 0.00368  158 TRP A CE2   
1279 C CE3   . TRP A 160 ? 0.42690 0.54429 0.52436 -0.04320 -0.02480 0.00690  158 TRP A CE3   
1280 C CZ2   . TRP A 160 ? 0.41706 0.49215 0.49429 -0.07195 -0.03191 0.00273  158 TRP A CZ2   
1281 C CZ3   . TRP A 160 ? 0.49612 0.59242 0.58773 -0.04451 -0.01968 0.00561  158 TRP A CZ3   
1282 C CH2   . TRP A 160 ? 0.45894 0.53555 0.54112 -0.05803 -0.02293 0.00394  158 TRP A CH2   
1283 N N     . PRO A 161 ? 0.29369 0.46137 0.38147 -0.05004 -0.06019 0.00472  159 PRO A N     
1284 C CA    . PRO A 161 ? 0.29476 0.45302 0.36763 -0.06096 -0.07052 -0.00054 159 PRO A CA    
1285 C C     . PRO A 161 ? 0.34474 0.48164 0.39879 -0.04988 -0.06964 -0.00517 159 PRO A C     
1286 O O     . PRO A 161 ? 0.34271 0.45876 0.37746 -0.05604 -0.07492 -0.01223 159 PRO A O     
1287 C CB    . PRO A 161 ? 0.32680 0.52508 0.41380 -0.06631 -0.07957 0.00511  159 PRO A CB    
1288 C CG    . PRO A 161 ? 0.34924 0.57740 0.45914 -0.06238 -0.07363 0.01300  159 PRO A CG    
1289 C CD    . PRO A 161 ? 0.29251 0.50128 0.40054 -0.04627 -0.06155 0.01248  159 PRO A CD    
1290 N N     . LEU A 162 ? 0.30065 0.44167 0.35815 -0.03366 -0.06341 -0.00106 160 LEU A N     
1291 C CA    . LEU A 162 ? 0.34723 0.47133 0.38785 -0.02432 -0.06192 -0.00300 160 LEU A CA    
1292 C C     . LEU A 162 ? 0.31320 0.40791 0.34225 -0.02257 -0.05419 -0.00779 160 LEU A C     
1293 O O     . LEU A 162 ? 0.33420 0.41306 0.34497 -0.02109 -0.05470 -0.01245 160 LEU A O     
1294 C CB    . LEU A 162 ? 0.30888 0.44448 0.35560 -0.00951 -0.05911 0.00444  160 LEU A CB    
1295 C CG    . LEU A 162 ? 0.34047 0.50537 0.39438 -0.00724 -0.06765 0.00932  160 LEU A CG    
1296 C CD1   . LEU A 162 ? 0.36384 0.53871 0.42636 0.00881  -0.06434 0.01695  160 LEU A CD1   
1297 C CD2   . LEU A 162 ? 0.36856 0.53099 0.40494 -0.00901 -0.07536 0.00709  160 LEU A CD2   
1298 N N     . VAL A 163 ? 0.31170 0.40122 0.35059 -0.02171 -0.04703 -0.00657 161 VAL A N     
1299 C CA    . VAL A 163 ? 0.30614 0.37109 0.33553 -0.02069 -0.04064 -0.01088 161 VAL A CA    
1300 C C     . VAL A 163 ? 0.37068 0.41863 0.38576 -0.03050 -0.04563 -0.01848 161 VAL A C     
1301 O O     . VAL A 163 ? 0.34144 0.36975 0.33926 -0.02645 -0.04374 -0.02385 161 VAL A O     
1302 C CB    . VAL A 163 ? 0.30633 0.37087 0.34880 -0.01876 -0.03352 -0.00798 161 VAL A CB    
1303 C CG1   . VAL A 163 ? 0.27934 0.32178 0.31281 -0.01639 -0.02740 -0.01153 161 VAL A CG1   
1304 C CG2   . VAL A 163 ? 0.27311 0.34956 0.32544 -0.00843 -0.03036 -0.00172 161 VAL A CG2   
1305 N N     . GLU A 164 ? 0.33214 0.38732 0.35290 -0.04343 -0.05253 -0.01874 162 GLU A N     
1306 C CA    . GLU A 164 ? 0.40833 0.44171 0.41250 -0.05492 -0.05950 -0.02596 162 GLU A CA    
1307 C C     . GLU A 164 ? 0.41735 0.44175 0.40043 -0.05324 -0.06631 -0.03239 162 GLU A C     
1308 O O     . GLU A 164 ? 0.43714 0.43335 0.39763 -0.05153 -0.06729 -0.04054 162 GLU A O     
1309 C CB    . GLU A 164 ? 0.43778 0.48442 0.45333 -0.07241 -0.06704 -0.02288 162 GLU A CB    
1310 C CG    . GLU A 164 ? 0.56527 0.58115 0.56378 -0.08618 -0.07327 -0.02888 162 GLU A CG    
1311 C CD    . GLU A 164 ? 0.71540 0.74550 0.72699 -0.10633 -0.07992 -0.02326 162 GLU A CD    
1312 O OE1   . GLU A 164 ? 0.81989 0.82304 0.81661 -0.12096 -0.08714 -0.02692 162 GLU A OE1   
1313 O OE2   . GLU A 164 ? 0.79310 0.86124 0.82892 -0.10726 -0.07800 -0.01468 162 GLU A OE2   
1314 N N     . ALA A 165 ? 0.37878 0.42703 0.36725 -0.05209 -0.07122 -0.02888 163 ALA A N     
1315 C CA    . ALA A 165 ? 0.38590 0.42908 0.35390 -0.05169 -0.07910 -0.03449 163 ALA A CA    
1316 C C     . ALA A 165 ? 0.39362 0.42235 0.34444 -0.03647 -0.07156 -0.03739 163 ALA A C     
1317 O O     . ALA A 165 ? 0.49062 0.50418 0.41699 -0.03477 -0.07607 -0.04512 163 ALA A O     
1318 C CB    . ALA A 165 ? 0.39390 0.46930 0.37326 -0.05261 -0.08587 -0.02836 163 ALA A CB    
1319 N N     . THR A 166 ? 0.38805 0.42276 0.35025 -0.02565 -0.06062 -0.03101 164 THR A N     
1320 C CA    . THR A 166 ? 0.36372 0.39239 0.31268 -0.01304 -0.05351 -0.03098 164 THR A CA    
1321 C C     . THR A 166 ? 0.42070 0.42830 0.35987 -0.00777 -0.04606 -0.03609 164 THR A C     
1322 O O     . THR A 166 ? 0.43211 0.43716 0.35864 0.00256  -0.04021 -0.03664 164 THR A O     
1323 C CB    . THR A 166 ? 0.33539 0.38089 0.29901 -0.00540 -0.04715 -0.02034 164 THR A CB    
1324 O OG1   . THR A 166 ? 0.33839 0.38622 0.32183 -0.00665 -0.04222 -0.01620 164 THR A OG1   
1325 C CG2   . THR A 166 ? 0.32993 0.39482 0.29694 -0.00576 -0.05459 -0.01519 164 THR A CG2   
1326 N N     . CYS A 167 ? 0.39752 0.39197 0.34147 -0.01395 -0.04615 -0.03908 165 CYS A N     
1327 C CA    . CYS A 167 ? 0.42113 0.39551 0.35468 -0.00697 -0.03970 -0.04363 165 CYS A CA    
1328 C C     . CYS A 167 ? 0.44991 0.40229 0.35333 -0.00292 -0.04430 -0.05434 165 CYS A C     
1329 O O     . CYS A 167 ? 0.49480 0.43280 0.38672 -0.01316 -0.05485 -0.06069 165 CYS A O     
1330 C CB    . CYS A 167 ? 0.40870 0.37248 0.35263 -0.01450 -0.03941 -0.04341 165 CYS A CB    
1331 S SG    . CYS A 167 ? 0.45230 0.39264 0.38428 -0.00369 -0.03171 -0.04774 165 CYS A SG    
1332 N N     . PRO A 168 ? 0.44846 0.39798 0.33738 0.01166  -0.03719 -0.05662 166 PRO A N     
1333 C CA    . PRO A 168 ? 0.50916 0.43605 0.36571 0.01916  -0.04094 -0.06808 166 PRO A CA    
1334 C C     . PRO A 168 ? 0.55333 0.44638 0.39644 0.01825  -0.04399 -0.07632 166 PRO A C     
1335 O O     . PRO A 168 ? 0.53860 0.42869 0.39490 0.01914  -0.03830 -0.07258 166 PRO A O     
1336 C CB    . PRO A 168 ? 0.48970 0.43069 0.33972 0.03659  -0.02984 -0.06549 166 PRO A CB    
1337 C CG    . PRO A 168 ? 0.52893 0.48607 0.40577 0.03706  -0.02053 -0.05534 166 PRO A CG    
1338 C CD    . PRO A 168 ? 0.41337 0.38031 0.31424 0.02194  -0.02541 -0.04871 166 PRO A CD    
1339 N N     . GLU A 169 ? 0.62895 0.49353 0.44273 0.01668  -0.05389 -0.08775 167 GLU A N     
1340 C CA    . GLU A 169 ? 0.65445 0.47954 0.45096 0.01413  -0.05920 -0.09561 167 GLU A CA    
1341 C C     . GLU A 169 ? 0.70803 0.52028 0.49288 0.03495  -0.04912 -0.09848 167 GLU A C     
1342 O O     . GLU A 169 ? 0.67325 0.46701 0.46094 0.03400  -0.04806 -0.09771 167 GLU A O     
1343 C CB    . GLU A 169 ? 0.73164 0.52464 0.49519 0.00747  -0.07368 -0.10794 167 GLU A CB    
1344 C CG    . GLU A 169 ? 0.79668 0.58071 0.56918 -0.01857 -0.08656 -0.10618 167 GLU A CG    
1345 C CD    . GLU A 169 ? 0.89378 0.64253 0.66005 -0.02490 -0.08917 -0.10760 167 GLU A CD    
1346 O OE1   . GLU A 169 ? 1.04246 0.76225 0.78630 -0.00770 -0.08479 -0.11428 167 GLU A OE1   
1347 N N     . ASP A 170 ? 0.66124 0.48523 0.43276 0.05439  -0.04158 -0.10100 168 ASP A N     
1348 C CA    . ASP A 170 ? 0.70690 0.52175 0.46457 0.07656  -0.03260 -0.10445 168 ASP A CA    
1349 C C     . ASP A 170 ? 0.64684 0.50329 0.43005 0.08652  -0.01824 -0.09285 168 ASP A C     
1350 O O     . ASP A 170 ? 0.76754 0.62883 0.54059 0.10686  -0.00967 -0.09434 168 ASP A O     
1351 C CB    . ASP A 170 ? 0.76515 0.55854 0.48170 0.09477  -0.03482 -0.11774 168 ASP A CB    
1352 C CG    . ASP A 170 ? 0.98256 0.73802 0.67160 0.08249  -0.05096 -0.12936 168 ASP A CG    
1353 O OD1   . ASP A 170 ? 1.06652 0.77854 0.73784 0.07866  -0.05911 -0.13659 168 ASP A OD1   
1354 O OD2   . ASP A 170 ? 1.11479 0.88245 0.79818 0.07640  -0.05624 -0.13099 168 ASP A OD2   
1355 N N     . ASP A 171 ? 0.59231 0.47861 0.40751 0.07299  -0.01589 -0.08118 169 ASP A N     
1356 C CA    . ASP A 171 ? 0.60245 0.52502 0.43883 0.08015  -0.00402 -0.07017 169 ASP A CA    
1357 C C     . ASP A 171 ? 0.47634 0.41414 0.34618 0.06631  -0.00238 -0.05941 169 ASP A C     
1358 O O     . ASP A 171 ? 0.46841 0.43539 0.35738 0.06432  0.00333  -0.04924 169 ASP A O     
1359 C CB    . ASP A 171 ? 0.58689 0.53567 0.41996 0.08355  -0.00100 -0.06624 169 ASP A CB    
1360 C CG    . ASP A 171 ? 0.65356 0.63516 0.49706 0.09489  0.01132  -0.05694 169 ASP A CG    
1361 O OD1   . ASP A 171 ? 0.58139 0.56215 0.42255 0.10771  0.01734  -0.05837 169 ASP A OD1   
1362 O OD2   . ASP A 171 ? 0.62838 0.63689 0.48202 0.09055  0.01441  -0.04748 169 ASP A OD2   
1363 N N     . ALA A 172 ? 0.49452 0.41159 0.36974 0.05688  -0.00745 -0.06126 170 ALA A N     
1364 C CA    . ALA A 172 ? 0.41176 0.34236 0.31560 0.04348  -0.00711 -0.05232 170 ALA A CA    
1365 C C     . ALA A 172 ? 0.41415 0.36684 0.33633 0.04951  0.00232  -0.04379 170 ALA A C     
1366 O O     . ALA A 172 ? 0.38659 0.35879 0.32965 0.04190  0.00404  -0.03537 170 ALA A O     
1367 C CB    . ALA A 172 ? 0.45292 0.35872 0.35678 0.03299  -0.01349 -0.05528 170 ALA A CB    
1368 N N     . ARG A 173 ? 0.39996 0.34898 0.31389 0.06325  0.00764  -0.04584 171 ARG A N     
1369 C CA    . ARG A 173 ? 0.39580 0.36793 0.32811 0.06718  0.01523  -0.03737 171 ARG A CA    
1370 C C     . ARG A 173 ? 0.36601 0.36948 0.30923 0.06585  0.01980  -0.02891 171 ARG A C     
1371 O O     . ARG A 173 ? 0.34086 0.35922 0.30426 0.05656  0.02078  -0.02044 171 ARG A O     
1372 C CB    . ARG A 173 ? 0.42801 0.39591 0.34842 0.08472  0.02002  -0.04067 171 ARG A CB    
1373 C CG    . ARG A 173 ? 0.42054 0.42106 0.35901 0.08995  0.02789  -0.03123 171 ARG A CG    
1374 C CD    . ARG A 173 ? 0.47132 0.47591 0.39652 0.11124  0.03333  -0.03416 171 ARG A CD    
1375 N NE    . ARG A 173 ? 0.52544 0.50150 0.44180 0.11723  0.03040  -0.03937 171 ARG A NE    
1376 C CZ    . ARG A 173 ? 0.64633 0.61434 0.54554 0.13789  0.03307  -0.04405 171 ARG A CZ    
1377 N NH1   . ARG A 173 ? 0.67546 0.66363 0.56400 0.15588  0.03929  -0.04517 171 ARG A NH1   
1378 N NH2   . ARG A 173 ? 0.69559 0.63486 0.58679 0.14180  0.02958  -0.04724 171 ARG A NH2   
1379 N N     . ALA A 174 ? 0.39257 0.40420 0.32023 0.07492  0.02214  -0.03096 172 ALA A N     
1380 C CA    . ALA A 174 ? 0.37057 0.41214 0.30645 0.07317  0.02678  -0.02125 172 ALA A CA    
1381 C C     . ALA A 174 ? 0.37638 0.41819 0.32219 0.05830  0.02136  -0.01651 172 ALA A C     
1382 O O     . ALA A 174 ? 0.34718 0.40752 0.30713 0.05166  0.02356  -0.00592 172 ALA A O     
1383 C CB    . ALA A 174 ? 0.37694 0.42778 0.29118 0.08731  0.03082  -0.02458 172 ALA A CB    
1384 N N     . TRP A 175 ? 0.33713 0.35819 0.27518 0.05284  0.01358  -0.02377 173 TRP A N     
1385 C CA    . TRP A 175 ? 0.33899 0.36217 0.28647 0.04110  0.00796  -0.01959 173 TRP A CA    
1386 C C     . TRP A 175 ? 0.32221 0.34869 0.29209 0.03260  0.00808  -0.01291 173 TRP A C     
1387 O O     . TRP A 175 ? 0.31513 0.35217 0.29521 0.02738  0.00777  -0.00468 173 TRP A O     
1388 C CB    . TRP A 175 ? 0.35167 0.35558 0.28763 0.03658  -0.00084 -0.02871 173 TRP A CB    
1389 C CG    . TRP A 175 ? 0.33139 0.33925 0.27911 0.02547  -0.00740 -0.02509 173 TRP A CG    
1390 C CD1   . TRP A 175 ? 0.35602 0.35705 0.31534 0.01643  -0.01223 -0.02611 173 TRP A CD1   
1391 C CD2   . TRP A 175 ? 0.31632 0.33777 0.26428 0.02371  -0.00987 -0.01939 173 TRP A CD2   
1392 N NE1   . TRP A 175 ? 0.35724 0.36933 0.32492 0.01057  -0.01725 -0.02177 173 TRP A NE1   
1393 C CE2   . TRP A 175 ? 0.34693 0.36974 0.30755 0.01518  -0.01625 -0.01761 173 TRP A CE2   
1394 C CE3   . TRP A 175 ? 0.36097 0.39513 0.29966 0.02904  -0.00698 -0.01449 173 TRP A CE3   
1395 C CZ2   . TRP A 175 ? 0.33355 0.36817 0.29713 0.01346  -0.02042 -0.01179 173 TRP A CZ2   
1396 C CZ3   . TRP A 175 ? 0.35324 0.39676 0.29400 0.02558  -0.01131 -0.00813 173 TRP A CZ3   
1397 C CH2   . TRP A 175 ? 0.38246 0.42523 0.33530 0.01864  -0.01824 -0.00716 173 TRP A CH2   
1398 N N     . TYR A 176 ? 0.30396 0.31921 0.27933 0.03182  0.00816  -0.01636 174 TYR A N     
1399 C CA    . TYR A 176 ? 0.30411 0.32177 0.29787 0.02470  0.00787  -0.01111 174 TYR A CA    
1400 C C     . TYR A 176 ? 0.28080 0.31302 0.28440 0.02585  0.01323  -0.00321 174 TYR A C     
1401 O O     . TYR A 176 ? 0.27972 0.31487 0.29514 0.01967  0.01205  0.00250  174 TYR A O     
1402 C CB    . TYR A 176 ? 0.31317 0.31533 0.30894 0.02232  0.00590  -0.01626 174 TYR A CB    
1403 C CG    . TYR A 176 ? 0.31255 0.30609 0.30663 0.01468  -0.00096 -0.01998 174 TYR A CG    
1404 C CD1   . TYR A 176 ? 0.29647 0.30034 0.30135 0.00898  -0.00402 -0.01558 174 TYR A CD1   
1405 C CD2   . TYR A 176 ? 0.29994 0.27526 0.28091 0.01308  -0.00508 -0.02737 174 TYR A CD2   
1406 C CE1   . TYR A 176 ? 0.29672 0.29973 0.30254 0.00191  -0.01046 -0.01779 174 TYR A CE1   
1407 C CE2   . TYR A 176 ? 0.33216 0.30322 0.31320 0.00284  -0.01253 -0.02949 174 TYR A CE2   
1408 C CZ    . TYR A 176 ? 0.30698 0.29540 0.30206 -0.00249 -0.01475 -0.02431 174 TYR A CZ    
1409 O OH    . TYR A 176 ? 0.33509 0.32622 0.33269 -0.01221 -0.02193 -0.02519 174 TYR A OH    
1410 N N     . TYR A 177 ? 0.30249 0.34475 0.30052 0.03374  0.01857  -0.00252 175 TYR A N     
1411 C CA    . TYR A 177 ? 0.31083 0.37293 0.31901 0.03204  0.02276  0.00697  175 TYR A CA    
1412 C C     . TYR A 177 ? 0.29923 0.36998 0.30891 0.02518  0.02140  0.01522  175 TYR A C     
1413 O O     . TYR A 177 ? 0.26945 0.34423 0.28948 0.01703  0.02030  0.02320  175 TYR A O     
1414 C CB    . TYR A 177 ? 0.29180 0.37051 0.29401 0.04302  0.02925  0.00740  175 TYR A CB    
1415 C CG    . TYR A 177 ? 0.32762 0.40104 0.32961 0.05136  0.03112  0.00231  175 TYR A CG    
1416 C CD1   . TYR A 177 ? 0.32077 0.37915 0.33080 0.04627  0.02778  0.00015  175 TYR A CD1   
1417 C CD2   . TYR A 177 ? 0.34810 0.43170 0.33967 0.06629  0.03641  -0.00021 175 TYR A CD2   
1418 C CE1   . TYR A 177 ? 0.35593 0.40870 0.36397 0.05460  0.02928  -0.00344 175 TYR A CE1   
1419 C CE2   . TYR A 177 ? 0.36907 0.44632 0.35832 0.07627  0.03775  -0.00441 175 TYR A CE2   
1420 C CZ    . TYR A 177 ? 0.38422 0.44514 0.38163 0.06969  0.03388  -0.00569 175 TYR A CZ    
1421 O OH    . TYR A 177 ? 0.39558 0.44915 0.38897 0.08014  0.03490  -0.00890 175 TYR A OH    
1422 N N     . ALA A 178 ? 0.27974 0.35035 0.27690 0.02818  0.02041  0.01333  176 ALA A N     
1423 C CA    . ALA A 178 ? 0.31414 0.39123 0.31038 0.02257  0.01865  0.02190  176 ALA A CA    
1424 C C     . ALA A 178 ? 0.29022 0.35348 0.29469 0.01501  0.01233  0.02366  176 ALA A C     
1425 O O     . ALA A 178 ? 0.30538 0.36966 0.31423 0.00876  0.01083  0.03296  176 ALA A O     
1426 C CB    . ALA A 178 ? 0.31977 0.39870 0.29902 0.02843  0.01806  0.01837  176 ALA A CB    
1427 N N     . LEU A 179 ? 0.28328 0.33340 0.28870 0.01577  0.00832  0.01528  177 LEU A N     
1428 C CA    . LEU A 179 ? 0.28560 0.32690 0.29918 0.01152  0.00329  0.01669  177 LEU A CA    
1429 C C     . LEU A 179 ? 0.30794 0.34556 0.33196 0.00783  0.00424  0.02055  177 LEU A C     
1430 O O     . LEU A 179 ? 0.29209 0.32362 0.31864 0.00487  0.00102  0.02603  177 LEU A O     
1431 C CB    . LEU A 179 ? 0.27014 0.30430 0.28452 0.01202  -0.00035 0.00816  177 LEU A CB    
1432 C CG    . LEU A 179 ? 0.29004 0.32628 0.29422 0.01301  -0.00470 0.00508  177 LEU A CG    
1433 C CD1   . LEU A 179 ? 0.33208 0.36217 0.33662 0.01043  -0.00873 -0.00306 177 LEU A CD1   
1434 C CD2   . LEU A 179 ? 0.31877 0.35924 0.32422 0.01259  -0.00887 0.01194  177 LEU A CD2   
1435 N N     . LEU A 180 ? 0.26904 0.30828 0.29713 0.00872  0.00784  0.01750  178 LEU A N     
1436 C CA    . LEU A 180 ? 0.27640 0.31304 0.31306 0.00476  0.00787  0.02064  178 LEU A CA    
1437 C C     . LEU A 180 ? 0.27950 0.32161 0.31651 -0.00144 0.00744  0.03076  178 LEU A C     
1438 O O     . LEU A 180 ? 0.29402 0.32543 0.33323 -0.00664 0.00346  0.03454  178 LEU A O     
1439 C CB    . LEU A 180 ? 0.26357 0.30460 0.30333 0.00770  0.01169  0.01683  178 LEU A CB    
1440 C CG    . LEU A 180 ? 0.29546 0.32587 0.33546 0.01085  0.01112  0.00864  178 LEU A CG    
1441 C CD1   . LEU A 180 ? 0.31406 0.34736 0.35361 0.01560  0.01477  0.00607  178 LEU A CD1   
1442 C CD2   . LEU A 180 ? 0.30872 0.33030 0.35526 0.00762  0.00805  0.00842  178 LEU A CD2   
1443 N N     . ASP A 181 ? 0.27164 0.32975 0.30481 -0.00110 0.01127  0.03554  179 ASP A N     
1444 C CA    . ASP A 181 ? 0.29116 0.35891 0.32558 -0.00949 0.01139  0.04728  179 ASP A CA    
1445 C C     . ASP A 181 ? 0.29370 0.34925 0.32156 -0.01404 0.00648  0.05387  179 ASP A C     
1446 O O     . ASP A 181 ? 0.30641 0.35357 0.33473 -0.02339 0.00253  0.06219  179 ASP A O     
1447 C CB    . ASP A 181 ? 0.26977 0.36349 0.30202 -0.00617 0.01815  0.05116  179 ASP A CB    
1448 C CG    . ASP A 181 ? 0.32610 0.43284 0.36459 -0.00049 0.02263  0.04673  179 ASP A CG    
1449 O OD1   . ASP A 181 ? 0.32779 0.42454 0.37348 -0.00264 0.01999  0.04317  179 ASP A OD1   
1450 O OD2   . ASP A 181 ? 0.27388 0.40084 0.30856 0.00767  0.02877  0.04682  179 ASP A OD2   
1451 N N     . TYR A 182 ? 0.28572 0.33793 0.30602 -0.00767 0.00553  0.05029  180 TYR A N     
1452 C CA    . TYR A 182 ? 0.26261 0.30317 0.27585 -0.00963 0.00034  0.05669  180 TYR A CA    
1453 C C     . TYR A 182 ? 0.30014 0.31837 0.31580 -0.00934 -0.00571 0.05417  180 TYR A C     
1454 O O     . TYR A 182 ? 0.31498 0.31775 0.32541 -0.01357 -0.01062 0.06177  180 TYR A O     
1455 C CB    . TYR A 182 ? 0.27170 0.31788 0.27637 -0.00231 0.00023  0.05308  180 TYR A CB    
1456 C CG    . TYR A 182 ? 0.31040 0.34799 0.30662 -0.00212 -0.00511 0.06010  180 TYR A CG    
1457 C CD1   . TYR A 182 ? 0.31597 0.34692 0.30753 -0.00944 -0.00706 0.07295  180 TYR A CD1   
1458 C CD2   . TYR A 182 ? 0.35031 0.38640 0.34260 0.00491  -0.00900 0.05455  180 TYR A CD2   
1459 C CE1   . TYR A 182 ? 0.33011 0.35036 0.31152 -0.00791 -0.01242 0.08016  180 TYR A CE1   
1460 C CE2   . TYR A 182 ? 0.31121 0.34111 0.29541 0.00702  -0.01431 0.06139  180 TYR A CE2   
1461 C CZ    . TYR A 182 ? 0.34172 0.36209 0.31977 0.00154  -0.01585 0.07411  180 TYR A CZ    
1462 O OH    . TYR A 182 ? 0.38477 0.39571 0.35255 0.00472  -0.02161 0.08184  180 TYR A OH    
1463 N N     . GLY A 183 ? 0.27928 0.29465 0.30119 -0.00400 -0.00544 0.04393  181 GLY A N     
1464 C CA    . GLY A 183 ? 0.30379 0.30191 0.32747 -0.00139 -0.00991 0.04098  181 GLY A CA    
1465 C C     . GLY A 183 ? 0.29931 0.28369 0.32253 -0.00836 -0.01241 0.04526  181 GLY A C     
1466 O O     . GLY A 183 ? 0.32757 0.29124 0.34408 -0.00761 -0.01807 0.04776  181 GLY A O     
1467 N N     . ALA A 184 ? 0.31689 0.31170 0.34587 -0.01469 -0.00904 0.04594  182 ALA A N     
1468 C CA    . ALA A 184 ? 0.33801 0.32142 0.36658 -0.02375 -0.01285 0.05015  182 ALA A CA    
1469 C C     . ALA A 184 ? 0.37214 0.34539 0.39209 -0.03316 -0.01745 0.06202  182 ALA A C     
1470 O O     . ALA A 184 ? 0.36700 0.31563 0.37944 -0.03878 -0.02450 0.06498  182 ALA A O     
1471 C CB    . ALA A 184 ? 0.33707 0.33970 0.37488 -0.02855 -0.00864 0.04981  182 ALA A CB    
1472 N N     . HIS A 185 ? 0.35085 0.34028 0.36918 -0.03476 -0.01406 0.06904  183 HIS A N     
1473 C CA    . HIS A 185 ? 0.37844 0.35889 0.38739 -0.04427 -0.01812 0.08219  183 HIS A CA    
1474 C C     . HIS A 185 ? 0.35665 0.30615 0.35305 -0.03818 -0.02534 0.08233  183 HIS A C     
1475 O O     . HIS A 185 ? 0.40186 0.32522 0.38780 -0.04599 -0.03264 0.08973  183 HIS A O     
1476 C CB    . HIS A 185 ? 0.35381 0.36107 0.36234 -0.04458 -0.01190 0.08903  183 HIS A CB    
1477 C CG    . HIS A 185 ? 0.45270 0.45385 0.45101 -0.05478 -0.01521 0.10437  183 HIS A CG    
1478 N ND1   . HIS A 185 ? 0.46627 0.46650 0.46481 -0.07208 -0.01809 0.11660  183 HIS A ND1   
1479 C CD2   . HIS A 185 ? 0.47274 0.46836 0.45959 -0.05121 -0.01671 0.11050  183 HIS A CD2   
1480 C CE1   . HIS A 185 ? 0.50585 0.49880 0.49303 -0.07943 -0.02089 0.13028  183 HIS A CE1   
1481 N NE2   . HIS A 185 ? 0.49410 0.48365 0.47356 -0.06600 -0.01998 0.12673  183 HIS A NE2   
1482 N N     . LEU A 186 ? 0.35807 0.30994 0.35439 -0.02415 -0.02406 0.07462  184 LEU A N     
1483 C CA    . LEU A 186 ? 0.37515 0.30292 0.36087 -0.01495 -0.03050 0.07454  184 LEU A CA    
1484 C C     . LEU A 186 ? 0.42471 0.32410 0.40566 -0.01306 -0.03618 0.06996  184 LEU A C     
1485 O O     . LEU A 186 ? 0.43659 0.30570 0.40293 -0.01131 -0.04360 0.07452  184 LEU A O     
1486 C CB    . LEU A 186 ? 0.35097 0.29345 0.34141 -0.00114 -0.02816 0.06625  184 LEU A CB    
1487 C CG    . LEU A 186 ? 0.34048 0.30330 0.32899 -0.00022 -0.02545 0.07012  184 LEU A CG    
1488 C CD1   . LEU A 186 ? 0.34232 0.31964 0.33673 0.01058  -0.02463 0.06042  184 LEU A CD1   
1489 C CD2   . LEU A 186 ? 0.39652 0.34597 0.37071 -0.00155 -0.03044 0.08255  184 LEU A CD2   
1490 N N     . LYS A 187 ? 0.40433 0.31092 0.39498 -0.01216 -0.03316 0.06068  185 LYS A N     
1491 C CA    . LYS A 187 ? 0.42357 0.30405 0.40756 -0.00957 -0.03839 0.05540  185 LYS A CA    
1492 C C     . LYS A 187 ? 0.47313 0.32706 0.44505 -0.02394 -0.04591 0.06371  185 LYS A C     
1493 O O     . LYS A 187 ? 0.50877 0.32884 0.46628 -0.02061 -0.05343 0.06112  185 LYS A O     
1494 C CB    . LYS A 187 ? 0.38982 0.28588 0.38604 -0.00798 -0.03342 0.04557  185 LYS A CB    
1495 C CG    . LYS A 187 ? 0.35579 0.26658 0.35945 0.00640  -0.02894 0.03689  185 LYS A CG    
1496 C CD    . LYS A 187 ? 0.32051 0.24972 0.33641 0.00521  -0.02313 0.02984  185 LYS A CD    
1497 C CE    . LYS A 187 ? 0.31446 0.25942 0.33800 0.01595  -0.01908 0.02310  185 LYS A CE    
1498 N NZ    . LYS A 187 ? 0.32712 0.26044 0.34480 0.02875  -0.02195 0.01938  185 LYS A NZ    
1499 N N     . ALA A 188 ? 0.40447 0.27258 0.38040 -0.03986 -0.04454 0.07407  186 ALA A N     
1500 C CA    . ALA A 188 ? 0.46992 0.31522 0.43509 -0.05726 -0.05254 0.08430  186 ALA A CA    
1501 C C     . ALA A 188 ? 0.53929 0.35735 0.48661 -0.05903 -0.05911 0.09530  186 ALA A C     
1502 O O     . ALA A 188 ? 0.61467 0.39421 0.54489 -0.06724 -0.06925 0.09992  186 ALA A O     
1503 C CB    . ALA A 188 ? 0.47743 0.35527 0.45618 -0.07454 -0.04805 0.09248  186 ALA A CB    
1504 N N     . VAL A 189 ? 0.51331 0.34742 0.46177 -0.05162 -0.05459 0.09973  187 VAL A N     
1505 C CA    . VAL A 189 ? 0.51803 0.33258 0.45046 -0.05634 -0.05997 0.11355  187 VAL A CA    
1506 C C     . VAL A 189 ? 0.56105 0.35036 0.47931 -0.03669 -0.06460 0.11035  187 VAL A C     
1507 O O     . VAL A 189 ? 0.63919 0.40207 0.53964 -0.03885 -0.07127 0.12168  187 VAL A O     
1508 C CB    . VAL A 189 ? 0.53845 0.38959 0.47866 -0.06394 -0.05250 0.12433  187 VAL A CB    
1509 C CG1   . VAL A 189 ? 0.53641 0.41607 0.49050 -0.08172 -0.04776 0.12905  187 VAL A CG1   
1510 C CG2   . VAL A 189 ? 0.49552 0.37509 0.44478 -0.04657 -0.04482 0.11551  187 VAL A CG2   
1511 N N     . VAL A 190 ? 0.50877 0.30727 0.43420 -0.01769 -0.06139 0.09672  188 VAL A N     
1512 C CA    . VAL A 190 ? 0.53407 0.31239 0.44740 0.00262  -0.06606 0.09357  188 VAL A CA    
1513 C C     . VAL A 190 ? 0.52421 0.29072 0.43786 0.01600  -0.06706 0.07957  188 VAL A C     
1514 O O     . VAL A 190 ? 0.50709 0.28505 0.43184 0.00981  -0.06335 0.07213  188 VAL A O     
1515 C CB    . VAL A 190 ? 0.52441 0.33494 0.44654 0.01459  -0.06093 0.09318  188 VAL A CB    
1516 C CG1   . VAL A 190 ? 0.54651 0.36652 0.46399 0.00349  -0.06028 0.10726  188 VAL A CG1   
1517 C CG2   . VAL A 190 ? 0.49485 0.34456 0.43894 0.01708  -0.05199 0.08185  188 VAL A CG2   
1518 N N     . ALA A 191 ? 0.57761 0.32210 0.47782 0.03594  -0.07206 0.07653  189 ALA A N     
1519 C CA    . ALA A 191 ? 0.58396 0.32432 0.48462 0.05268  -0.07144 0.06330  189 ALA A CA    
1520 C C     . ALA A 191 ? 0.51174 0.29964 0.43818 0.05471  -0.06120 0.05494  189 ALA A C     
1521 O O     . ALA A 191 ? 0.50312 0.32232 0.44173 0.05801  -0.05684 0.05670  189 ALA A O     
1522 C CB    . ALA A 191 ? 0.65644 0.37723 0.54146 0.07756  -0.07661 0.06230  189 ALA A CB    
1523 N N     . ASN A 192 ? 0.47576 0.26714 0.40883 0.05136  -0.05821 0.04623  190 ASN A N     
1524 C CA    . ASN A 192 ? 0.42136 0.25243 0.37667 0.05035  -0.04916 0.03932  190 ASN A CA    
1525 C C     . ASN A 192 ? 0.40624 0.26554 0.37164 0.06529  -0.04558 0.03711  190 ASN A C     
1526 O O     . ASN A 192 ? 0.45298 0.30935 0.41412 0.08327  -0.04672 0.03247  190 ASN A O     
1527 C CB    . ASN A 192 ? 0.42845 0.25261 0.38352 0.05249  -0.04810 0.02981  190 ASN A CB    
1528 C CG    . ASN A 192 ? 0.41245 0.27346 0.38781 0.05312  -0.03933 0.02328  190 ASN A CG    
1529 O OD1   . ASN A 192 ? 0.37656 0.26544 0.36623 0.04681  -0.03443 0.02556  190 ASN A OD1   
1530 N ND2   . ASN A 192 ? 0.38338 0.24238 0.35776 0.06051  -0.03773 0.01511  190 ASN A ND2   
1531 N N     . PRO A 193 ? 0.42635 0.31432 0.40420 0.05878  -0.04174 0.04040  191 PRO A N     
1532 C CA    . PRO A 193 ? 0.41770 0.33280 0.40449 0.07057  -0.04034 0.03902  191 PRO A CA    
1533 C C     . PRO A 193 ? 0.36472 0.30123 0.36407 0.07889  -0.03583 0.03045  191 PRO A C     
1534 O O     . PRO A 193 ? 0.38973 0.34436 0.39377 0.09239  -0.03630 0.02968  191 PRO A O     
1535 C CB    . PRO A 193 ? 0.37070 0.30837 0.36592 0.05824  -0.03748 0.04251  191 PRO A CB    
1536 C CG    . PRO A 193 ? 0.36257 0.27991 0.34763 0.04488  -0.03901 0.05000  191 PRO A CG    
1537 C CD    . PRO A 193 ? 0.36954 0.26546 0.35112 0.04137  -0.03954 0.04622  191 PRO A CD    
1538 N N     . SER A 194 ? 0.36328 0.30024 0.36818 0.07129  -0.03161 0.02504  192 SER A N     
1539 C CA    . SER A 194 ? 0.35384 0.31099 0.36958 0.07764  -0.02684 0.01833  192 SER A CA    
1540 C C     . SER A 194 ? 0.38701 0.33477 0.39386 0.09697  -0.02858 0.01526  192 SER A C     
1541 O O     . SER A 194 ? 0.38445 0.35607 0.40089 0.10507  -0.02425 0.01146  192 SER A O     
1542 C CB    . SER A 194 ? 0.35677 0.31275 0.37728 0.06579  -0.02261 0.01425  192 SER A CB    
1543 O OG    . SER A 194 ? 0.38510 0.35641 0.41519 0.05219  -0.01970 0.01575  192 SER A OG    
1544 N N     . ARG A 195 ? 0.38362 0.29726 0.37110 0.10510  -0.03488 0.01720  193 ARG A N     
1545 C CA    . ARG A 195 ? 0.42475 0.32805 0.40038 0.12790  -0.03704 0.01388  193 ARG A CA    
1546 C C     . ARG A 195 ? 0.45209 0.38841 0.43786 0.14308  -0.03600 0.01638  193 ARG A C     
1547 O O     . ARG A 195 ? 0.46877 0.41293 0.45135 0.16386  -0.03497 0.01315  193 ARG A O     
1548 C CB    . ARG A 195 ? 0.49276 0.34697 0.44204 0.13327  -0.04573 0.01611  193 ARG A CB    
1549 C CG    . ARG A 195 ? 0.47857 0.30004 0.41612 0.11961  -0.04840 0.01315  193 ARG A CG    
1550 C CD    . ARG A 195 ? 0.55176 0.32282 0.46294 0.11949  -0.05861 0.01735  193 ARG A CD    
1551 N NE    . ARG A 195 ? 0.56307 0.30354 0.46259 0.10505  -0.06273 0.01446  193 ARG A NE    
1552 C CZ    . ARG A 195 ? 0.62816 0.31940 0.50240 0.10088  -0.07297 0.01697  193 ARG A CZ    
1553 N NH1   . ARG A 195 ? 0.70877 0.37213 0.56520 0.11047  -0.07988 0.02299  193 ARG A NH1   
1554 N NH2   . ARG A 195 ? 0.58108 0.24939 0.44657 0.08624  -0.07728 0.01378  193 ARG A NH2   
1555 N N     . ARG A 196 ? 0.41656 0.37423 0.41378 0.13387  -0.03649 0.02205  194 ARG A N     
1556 C CA    . ARG A 196 ? 0.41639 0.41006 0.42523 0.14517  -0.03667 0.02497  194 ARG A CA    
1557 C C     . ARG A 196 ? 0.38992 0.42759 0.42226 0.13582  -0.03063 0.02278  194 ARG A C     
1558 O O     . ARG A 196 ? 0.41778 0.49058 0.46295 0.13926  -0.03147 0.02588  194 ARG A O     
1559 C CB    . ARG A 196 ? 0.37606 0.36630 0.38063 0.14143  -0.04238 0.03256  194 ARG A CB    
1560 C CG    . ARG A 196 ? 0.47693 0.42101 0.45650 0.14934  -0.04913 0.03674  194 ARG A CG    
1561 C CD    . ARG A 196 ? 0.44366 0.38660 0.41761 0.14851  -0.05472 0.04569  194 ARG A CD    
1562 N NE    . ARG A 196 ? 0.44075 0.38433 0.41846 0.12525  -0.05332 0.04886  194 ARG A NE    
1563 C CZ    . ARG A 196 ? 0.42106 0.39795 0.41315 0.11555  -0.05133 0.04943  194 ARG A CZ    
1564 N NH1   . ARG A 196 ? 0.39912 0.41270 0.40526 0.12338  -0.05123 0.04771  194 ARG A NH1   
1565 N NH2   . ARG A 196 ? 0.43203 0.40600 0.42351 0.09755  -0.04980 0.05181  194 ARG A NH2   
1566 N N     . SER A 197 ? 0.35859 0.39447 0.39595 0.12356  -0.02546 0.01815  195 SER A N     
1567 C CA    . SER A 197 ? 0.34182 0.41403 0.39821 0.11594  -0.01995 0.01648  195 SER A CA    
1568 C C     . SER A 197 ? 0.41055 0.50552 0.47131 0.13405  -0.01640 0.01510  195 SER A C     
1569 O O     . SER A 197 ? 0.36770 0.44149 0.41429 0.14935  -0.01589 0.01162  195 SER A O     
1570 C CB    . SER A 197 ? 0.35942 0.41979 0.41727 0.09914  -0.01581 0.01275  195 SER A CB    
1571 O OG    . SER A 197 ? 0.31842 0.40794 0.39105 0.09338  -0.01058 0.01160  195 SER A OG    
1572 N N     . ALA A 198 ? 0.32586 0.46515 0.40540 0.13219  -0.01429 0.01804  196 ALA A N     
1573 C CA    . ALA A 198 ? 0.37870 0.54931 0.46571 0.14776  -0.00938 0.01819  196 ALA A CA    
1574 C C     . ALA A 198 ? 0.38633 0.54746 0.46939 0.14639  -0.00269 0.01333  196 ALA A C     
1575 O O     . ALA A 198 ? 0.44650 0.62062 0.52681 0.16479  0.00161  0.01185  196 ALA A O     
1576 C CB    . ALA A 198 ? 0.35856 0.58174 0.46894 0.13939  -0.00882 0.02389  196 ALA A CB    
1577 N N     . HIS A 199 ? 0.35584 0.49553 0.43721 0.12694  -0.00171 0.01086  197 HIS A N     
1578 C CA    . HIS A 199 ? 0.37589 0.50793 0.45404 0.12331  0.00395  0.00699  197 HIS A CA    
1579 C C     . HIS A 199 ? 0.42900 0.51521 0.48575 0.12847  0.00175  0.00115  197 HIS A C     
1580 O O     . HIS A 199 ? 0.45976 0.53633 0.51188 0.12463  0.00520  -0.00245 197 HIS A O     
1581 C CB    . HIS A 199 ? 0.39920 0.53937 0.48920 0.09924  0.00602  0.00858  197 HIS A CB    
1582 C CG    . HIS A 199 ? 0.41445 0.58694 0.52129 0.08825  0.00418  0.01397  197 HIS A CG    
1583 N ND1   . HIS A 199 ? 0.42807 0.64402 0.54946 0.09274  0.00665  0.01883  197 HIS A ND1   
1584 C CD2   . HIS A 199 ? 0.36532 0.53401 0.47554 0.07340  -0.00066 0.01528  197 HIS A CD2   
1585 C CE1   . HIS A 199 ? 0.45499 0.69150 0.58858 0.07884  0.00242  0.02297  197 HIS A CE1   
1586 N NE2   . HIS A 199 ? 0.36771 0.57419 0.49334 0.06779  -0.00214 0.02020  197 HIS A NE2   
1587 N N     . HIS A 200 ? 0.42036 0.47784 0.46330 0.13571  -0.00467 0.00082  198 HIS A N     
1588 C CA    . HIS A 200 ? 0.50245 0.51496 0.52347 0.13941  -0.00849 -0.00399 198 HIS A CA    
1589 C C     . HIS A 200 ? 0.45563 0.46263 0.46365 0.15808  -0.00578 -0.01000 198 HIS A C     
1590 O O     . HIS A 200 ? 0.47830 0.49905 0.48297 0.17981  -0.00470 -0.01036 198 HIS A O     
1591 C CB    . HIS A 200 ? 0.48261 0.46638 0.48966 0.14538  -0.01640 -0.00155 198 HIS A CB    
1592 C CG    . HIS A 200 ? 0.52399 0.45878 0.50756 0.14536  -0.02219 -0.00517 198 HIS A CG    
1593 N ND1   . HIS A 200 ? 0.50920 0.42484 0.49128 0.12496  -0.02387 -0.00510 198 HIS A ND1   
1594 C CD2   . HIS A 200 ? 0.56857 0.46856 0.52805 0.16266  -0.02785 -0.00845 198 HIS A CD2   
1595 C CE1   . HIS A 200 ? 0.58085 0.45440 0.54059 0.12725  -0.03055 -0.00780 198 HIS A CE1   
1596 N NE2   . HIS A 200 ? 0.65089 0.51060 0.59492 0.14980  -0.03348 -0.01029 198 HIS A NE2   
1597 N N     . THR A 201 ? 0.72966 0.81494 0.37141 0.23574  -0.14368 0.10987  199 THR A N     
1598 C CA    . THR A 201 ? 0.69965 0.75873 0.37196 0.23940  -0.13893 0.10984  199 THR A CA    
1599 C C     . THR A 201 ? 0.73883 0.74419 0.39071 0.21793  -0.11723 0.13152  199 THR A C     
1600 O O     . THR A 201 ? 0.85616 0.85381 0.47650 0.19920  -0.10536 0.14483  199 THR A O     
1601 C CB    . THR A 201 ? 0.64932 0.75366 0.37349 0.23619  -0.14085 0.07585  199 THR A CB    
1602 O OG1   . THR A 201 ? 0.75811 0.86300 0.48336 0.21163  -0.12421 0.06794  199 THR A OG1   
1603 C CG2   . THR A 201 ? 0.72705 0.89279 0.47106 0.24471  -0.15980 0.05068  199 THR A CG2   
1604 N N     . ARG A 202 ? 0.78462 0.75586 0.45617 0.21945  -0.11146 0.13332  200 ARG A N     
1605 C CA    . ARG A 202 ? 0.82644 0.75065 0.48677 0.19576  -0.09154 0.14816  200 ARG A CA    
1606 C C     . ARG A 202 ? 0.80296 0.72793 0.50034 0.19455  -0.08590 0.12903  200 ARG A C     
1607 O O     . ARG A 202 ? 0.77387 0.72180 0.50329 0.21492  -0.09703 0.11109  200 ARG A O     
1608 C CB    . ARG A 202 ? 0.90317 0.76072 0.53339 0.19539  -0.09002 0.17927  200 ARG A CB    
1609 C CG    . ARG A 202 ? 0.95664 0.78778 0.59824 0.22513  -0.10421 0.17893  200 ARG A CG    
1610 C CD    . ARG A 202 ? 0.89469 0.70149 0.56597 0.22616  -0.09719 0.16404  200 ARG A CD    
1611 N NE    . ARG A 202 ? 0.99262 0.75988 0.66683 0.25134  -0.10612 0.16682  200 ARG A NE    
1612 C CZ    . ARG A 202 ? 0.91627 0.71470 0.62289 0.28021  -0.11673 0.14583  200 ARG A CZ    
1613 N NH1   . ARG A 202 ? 0.96277 0.83150 0.70514 0.28433  -0.12009 0.12109  200 ARG A NH1   
1614 N NH2   . ARG A 202 ? 0.84071 0.60138 0.54631 0.30398  -0.12339 0.14887  200 ARG A NH2   
1615 N N     . GLN A 203 ? 0.67273 0.57893 0.36753 0.16954  -0.06800 0.13227  201 GLN A N     
1616 C CA    . GLN A 203 ? 0.65683 0.56467 0.39172 0.16053  -0.05994 0.11190  201 GLN A CA    
1617 C C     . GLN A 203 ? 0.68655 0.53539 0.41934 0.16840  -0.05914 0.12002  201 GLN A C     
1618 O O     . GLN A 203 ? 0.76778 0.56433 0.46724 0.17251  -0.06139 0.14351  201 GLN A O     
1619 C CB    . GLN A 203 ? 0.59985 0.51621 0.34410 0.12684  -0.04097 0.10654  201 GLN A CB    
1620 C CG    . GLN A 203 ? 0.59525 0.55989 0.33375 0.12066  -0.03963 0.09887  201 GLN A CG    
1621 C CD    . GLN A 203 ? 0.47864 0.44619 0.21569 0.09302  -0.02063 0.10176  201 GLN A CD    
1622 O OE1   . GLN A 203 ? 0.49062 0.44625 0.25191 0.07678  -0.01090 0.09527  201 GLN A OE1   
1623 N NE2   . GLN A 203 ? 0.53609 0.52484 0.24349 0.08936  -0.01555 0.11119  201 GLN A NE2   
1624 N N     . SER A 204 ? 0.72663 0.58488 0.49800 0.16712  -0.05455 0.09764  202 SER A N     
1625 C CA    . SER A 204 ? 0.74502 0.54923 0.51503 0.17128  -0.05087 0.09821  202 SER A CA    
1626 C C     . SER A 204 ? 0.75237 0.50798 0.50046 0.13892  -0.03764 0.11213  202 SER A C     
1627 O O     . SER A 204 ? 0.73022 0.50849 0.47694 0.11262  -0.02821 0.11620  202 SER A O     
1628 C CB    . SER A 204 ? 0.67401 0.50931 0.48749 0.17449  -0.04595 0.07014  202 SER A CB    
1629 O OG    . SER A 204 ? 0.63555 0.49912 0.46994 0.14482  -0.03300 0.05803  202 SER A OG    
1630 N N     . THR A 205 ? 0.74658 0.43590 0.47821 0.14186  -0.03779 0.11797  203 THR A N     
1631 C CA    . THR A 205 ? 0.79757 0.44013 0.51401 0.10787  -0.02707 0.12687  203 THR A CA    
1632 C C     . THR A 205 ? 0.69728 0.38590 0.44460 0.07992  -0.01513 0.10887  203 THR A C     
1633 O O     . THR A 205 ? 0.69560 0.41497 0.47212 0.08778  -0.01394 0.08561  203 THR A O     
1634 C CB    . THR A 205 ? 0.78234 0.35410 0.48767 0.11679  -0.03060 0.12212  203 THR A CB    
1635 O OG1   . THR A 205 ? 0.88650 0.43419 0.57850 0.13969  -0.04126 0.13441  203 THR A OG1   
1636 C CG2   . THR A 205 ? 0.80225 0.33188 0.49761 0.07666  -0.02192 0.12758  203 THR A CG2   
1637 N N     . PHE A 206 ? 0.64922 0.34486 0.38954 0.04808  -0.00585 0.12108  204 PHE A N     
1638 C CA    . PHE A 206 ? 0.58927 0.32879 0.35767 0.02524  0.00346  0.10581  204 PHE A CA    
1639 C C     . PHE A 206 ? 0.54985 0.25720 0.32469 0.00996  0.00537  0.09338  204 PHE A C     
1640 O O     . PHE A 206 ? 0.51661 0.25480 0.31536 0.00796  0.00783  0.07390  204 PHE A O     
1641 C CB    . PHE A 206 ? 0.57981 0.34691 0.34221 0.00011  0.01288  0.12096  204 PHE A CB    
1642 C CG    . PHE A 206 ? 0.48694 0.30396 0.27888 -0.01703 0.02059  0.10595  204 PHE A CG    
1643 C CD1   . PHE A 206 ? 0.43059 0.28963 0.24724 -0.00253 0.01886  0.08629  204 PHE A CD1   
1644 C CD2   . PHE A 206 ? 0.56235 0.38496 0.35777 -0.04804 0.02896  0.11276  204 PHE A CD2   
1645 C CE1   . PHE A 206 ? 0.47958 0.37700 0.31924 -0.01412 0.02430  0.07485  204 PHE A CE1   
1646 C CE2   . PHE A 206 ? 0.51726 0.38947 0.34048 -0.05849 0.03379  0.09942  204 PHE A CE2   
1647 C CZ    . PHE A 206 ? 0.46297 0.36865 0.30592 -0.03948 0.03102  0.08121  204 PHE A CZ    
1648 N N     . GLU A 207 ? 0.66925 0.31180 0.41964 -0.00176 0.00351  0.10449  205 GLU A N     
1649 C CA    . GLU A 207 ? 0.68786 0.29495 0.43978 -0.01674 0.00276  0.08911  205 GLU A CA    
1650 C C     . GLU A 207 ? 0.68758 0.29447 0.44943 0.01216  -0.00124 0.06463  205 GLU A C     
1651 O O     . GLU A 207 ? 0.65882 0.24404 0.41203 0.04410  -0.00697 0.06428  205 GLU A O     
1652 C CB    . GLU A 207 ? 0.78877 0.31360 0.50882 -0.03174 -0.00067 0.10424  205 GLU A CB    
1653 C CG    . GLU A 207 ? 0.94165 0.47452 0.66376 -0.07580 0.00649  0.11885  205 GLU A CG    
1654 C CD    . GLU A 207 ? 0.95755 0.51570 0.70123 -0.10222 0.00778  0.09845  205 GLU A CD    
1655 O OE1   . GLU A 207 ? 1.00103 0.62326 0.76738 -0.12237 0.01487  0.10117  205 GLU A OE1   
1656 O OE2   . GLU A 207 ? 1.01162 0.53064 0.75032 -0.09980 0.00084  0.07787  205 GLU A OE2   
1657 N N     . GLY A 208 ? 0.63174 0.26677 0.41121 0.00202  0.00204  0.04481  206 GLY A N     
1658 C CA    . GLY A 208 ? 0.63637 0.27902 0.42372 0.02538  0.00211  0.02241  206 GLY A CA    
1659 C C     . GLY A 208 ? 0.61079 0.31191 0.42191 0.04724  0.00527  0.01861  206 GLY A C     
1660 O O     . GLY A 208 ? 0.56971 0.28304 0.38955 0.06761  0.00753  0.00243  206 GLY A O     
1661 N N     . SER A 209 ? 0.52514 0.26461 0.34714 0.04230  0.00613  0.03145  207 SER A N     
1662 C CA    . SER A 209 ? 0.51009 0.29884 0.35357 0.06079  0.00639  0.02699  207 SER A CA    
1663 C C     . SER A 209 ? 0.44745 0.28005 0.31347 0.05074  0.01327  0.01499  207 SER A C     
1664 O O     . SER A 209 ? 0.44636 0.27955 0.31098 0.03064  0.01641  0.01387  207 SER A O     
1665 C CB    . SER A 209 ? 0.49632 0.30345 0.33629 0.06129  0.00271  0.04282  207 SER A CB    
1666 O OG    . SER A 209 ? 0.45987 0.28955 0.30352 0.03722  0.00813  0.04784  207 SER A OG    
1667 N N     . ARG A 210 ? 0.41199 0.28256 0.29933 0.06444  0.01452  0.00720  208 ARG A N     
1668 C CA    . ARG A 210 ? 0.37347 0.27927 0.27964 0.05388  0.02103  -0.00009 208 ARG A CA    
1669 C C     . ARG A 210 ? 0.40636 0.32634 0.31409 0.03797  0.02034  0.00729  208 ARG A C     
1670 O O     . ARG A 210 ? 0.38344 0.31122 0.29455 0.02568  0.02410  0.00535  208 ARG A O     
1671 C CB    . ARG A 210 ? 0.38694 0.33010 0.31796 0.06639  0.02242  -0.00843 208 ARG A CB    
1672 C CG    . ARG A 210 ? 0.37856 0.34871 0.32662 0.05342  0.03041  -0.01376 208 ARG A CG    
1673 C CD    . ARG A 210 ? 0.36745 0.37678 0.34406 0.05910  0.03105  -0.02106 208 ARG A CD    
1674 N NE    . ARG A 210 ? 0.29994 0.32684 0.29071 0.04376  0.04033  -0.02368 208 ARG A NE    
1675 C CZ    . ARG A 210 ? 0.35367 0.38949 0.34779 0.04189  0.05255  -0.02711 208 ARG A CZ    
1676 N NH1   . ARG A 210 ? 0.39273 0.42398 0.37866 0.05678  0.05683  -0.03264 208 ARG A NH1   
1677 N NH2   . ARG A 210 ? 0.34645 0.39345 0.34934 0.02549  0.06123  -0.02484 208 ARG A NH2   
1678 N N     . ARG A 211 ? 0.36027 0.28550 0.26335 0.04085  0.01537  0.01555  209 ARG A N     
1679 C CA    . ARG A 211 ? 0.36850 0.31366 0.27369 0.02991  0.01653  0.01897  209 ARG A CA    
1680 C C     . ARG A 211 ? 0.39782 0.33098 0.29257 0.01304  0.01971  0.02676  209 ARG A C     
1681 O O     . ARG A 211 ? 0.36243 0.31764 0.26497 0.00499  0.02227  0.02583  209 ARG A O     
1682 C CB    . ARG A 211 ? 0.37402 0.33391 0.27322 0.03871  0.01127  0.02345  209 ARG A CB    
1683 C CG    . ARG A 211 ? 0.36497 0.30124 0.23821 0.03998  0.00899  0.03999  209 ARG A CG    
1684 C CD    . ARG A 211 ? 0.33930 0.29463 0.20310 0.05412  0.00163  0.04305  209 ARG A CD    
1685 N NE    . ARG A 211 ? 0.41656 0.34840 0.24888 0.05693  -0.00064 0.06335  209 ARG A NE    
1686 C CZ    . ARG A 211 ? 0.47593 0.37153 0.29323 0.06949  -0.00692 0.07320  209 ARG A CZ    
1687 N NH1   . ARG A 211 ? 0.45788 0.34223 0.29091 0.08186  -0.01038 0.06195  209 ARG A NH1   
1688 N NH2   . ARG A 211 ? 0.51577 0.38406 0.29966 0.07060  -0.00879 0.09542  209 ARG A NH2   
1689 N N     . GLN A 212 ? 0.40331 0.30254 0.28193 0.00755  0.01877  0.03359  210 GLN A N     
1690 C CA    . GLN A 212 ? 0.41267 0.30441 0.28694 -0.01386 0.02077  0.03784  210 GLN A CA    
1691 C C     . GLN A 212 ? 0.41190 0.31608 0.29735 -0.01871 0.02102  0.02603  210 GLN A C     
1692 O O     . GLN A 212 ? 0.39440 0.32203 0.28836 -0.03083 0.02140  0.02651  210 GLN A O     
1693 C CB    . GLN A 212 ? 0.45873 0.30116 0.31231 -0.02124 0.01828  0.04479  210 GLN A CB    
1694 C CG    . GLN A 212 ? 0.50323 0.33708 0.35442 -0.04956 0.01886  0.04794  210 GLN A CG    
1695 C CD    . GLN A 212 ? 0.61337 0.38623 0.44164 -0.05953 0.01546  0.05389  210 GLN A CD    
1696 O OE1   . GLN A 212 ? 0.55140 0.28490 0.36803 -0.04496 0.01110  0.04390  210 GLN A OE1   
1697 N NE2   . GLN A 212 ? 0.59261 0.35586 0.41358 -0.08417 0.01831  0.07005  210 GLN A NE2   
1698 N N     . LYS A 213 ? 0.36880 0.26255 0.25396 -0.00742 0.02104  0.01599  211 LYS A N     
1699 C CA    . LYS A 213 ? 0.37975 0.28402 0.26811 -0.01106 0.02182  0.00769  211 LYS A CA    
1700 C C     . LYS A 213 ? 0.38350 0.31999 0.28731 -0.00777 0.02360  0.00859  211 LYS A C     
1701 O O     . LYS A 213 ? 0.36466 0.31383 0.27019 -0.01310 0.02179  0.00809  211 LYS A O     
1702 C CB    . LYS A 213 ? 0.39576 0.28434 0.27663 0.00019  0.02472  -0.00251 211 LYS A CB    
1703 C CG    . LYS A 213 ? 0.45404 0.30226 0.31585 0.00028  0.02181  -0.00792 211 LYS A CG    
1704 C CD    . LYS A 213 ? 0.43613 0.27621 0.29270 0.01891  0.02686  -0.02050 211 LYS A CD    
1705 C CE    . LYS A 213 ? 0.50610 0.29822 0.34151 0.02474  0.02303  -0.02880 211 LYS A CE    
1706 N NZ    . LYS A 213 ? 0.52120 0.29170 0.35682 0.03552  0.01895  -0.01850 211 LYS A NZ    
1707 N N     . ARG A 214 ? 0.36473 0.31234 0.27853 0.00208  0.02527  0.00892  212 ARG A N     
1708 C CA    . ARG A 214 ? 0.32136 0.28962 0.24757 0.00459  0.02573  0.00778  212 ARG A CA    
1709 C C     . ARG A 214 ? 0.35158 0.33596 0.27992 -0.00051 0.02369  0.01145  212 ARG A C     
1710 O O     . ARG A 214 ? 0.34686 0.34040 0.27985 0.00104  0.02223  0.01060  212 ARG A O     
1711 C CB    . ARG A 214 ? 0.30770 0.28559 0.24275 0.01292  0.02496  0.00462  212 ARG A CB    
1712 C CG    . ARG A 214 ? 0.30359 0.28183 0.24797 0.01776  0.02711  -0.00134 212 ARG A CG    
1713 C CD    . ARG A 214 ? 0.31962 0.31319 0.27360 0.02506  0.02221  -0.00607 212 ARG A CD    
1714 N NE    . ARG A 214 ? 0.33027 0.33338 0.28746 0.02374  0.01924  -0.00993 212 ARG A NE    
1715 C CZ    . ARG A 214 ? 0.32067 0.32672 0.29073 0.02018  0.01903  -0.01777 212 ARG A CZ    
1716 N NH1   . ARG A 214 ? 0.32803 0.33402 0.31100 0.01409  0.02326  -0.01982 212 ARG A NH1   
1717 N NH2   . ARG A 214 ? 0.33804 0.34600 0.30711 0.02223  0.01541  -0.02410 212 ARG A NH2   
1718 N N     . ALA A 215 ? 0.34123 0.33143 0.26609 -0.00548 0.02402  0.01675  213 ALA A N     
1719 C CA    . ALA A 215 ? 0.30778 0.32620 0.23962 -0.00981 0.02498  0.01947  213 ALA A CA    
1720 C C     . ALA A 215 ? 0.37924 0.40565 0.31497 -0.02081 0.02164  0.01993  213 ALA A C     
1721 O O     . ALA A 215 ? 0.36171 0.41731 0.30968 -0.01738 0.01978  0.01827  213 ALA A O     
1722 C CB    . ALA A 215 ? 0.33284 0.35775 0.25709 -0.01597 0.02903  0.02792  213 ALA A CB    
1723 N N     A GLU A 216 ? 0.36223 0.36401 0.28727 -0.03212 0.01925  0.02023  214 GLU A N     
1724 N N     B GLU A 216 ? 0.36271 0.36423 0.28770 -0.03174 0.01918  0.02003  214 GLU A N     
1725 C CA    A GLU A 216 ? 0.39600 0.40588 0.32228 -0.04393 0.01302  0.01724  214 GLU A CA    
1726 C CA    B GLU A 216 ? 0.39596 0.40647 0.32252 -0.04402 0.01304  0.01732  214 GLU A CA    
1727 C C     A GLU A 216 ? 0.38290 0.40119 0.30991 -0.03163 0.00861  0.01306  214 GLU A C     
1728 C C     B GLU A 216 ? 0.38443 0.40146 0.31058 -0.03239 0.00836  0.01283  214 GLU A C     
1729 O O     A GLU A 216 ? 0.38656 0.43307 0.32231 -0.03216 0.00205  0.01256  214 GLU A O     
1730 O O     B GLU A 216 ? 0.38737 0.43046 0.32059 -0.03446 0.00126  0.01190  214 GLU A O     
1731 C CB    A GLU A 216 ? 0.42132 0.39419 0.33062 -0.05650 0.01036  0.01396  214 GLU A CB    
1732 C CB    B GLU A 216 ? 0.42394 0.39873 0.33433 -0.05815 0.01044  0.01471  214 GLU A CB    
1733 C CG    A GLU A 216 ? 0.48589 0.43487 0.38790 -0.06588 0.01425  0.02168  214 GLU A CG    
1734 C CG    B GLU A 216 ? 0.55522 0.53659 0.47009 -0.08350 0.00840  0.01865  214 GLU A CG    
1735 C CD    A GLU A 216 ? 0.54200 0.44094 0.42381 -0.07180 0.01099  0.01667  214 GLU A CD    
1736 C CD    B GLU A 216 ? 0.45370 0.48773 0.39021 -0.09204 0.00343  0.01704  214 GLU A CD    
1737 O OE1   A GLU A 216 ? 0.50996 0.39650 0.38270 -0.06647 0.00732  0.00462  214 GLU A OE1   
1738 O OE1   B GLU A 216 ? 0.58384 0.62444 0.51872 -0.09530 -0.00665 0.00826  214 GLU A OE1   
1739 O OE2   A GLU A 216 ? 0.58750 0.45625 0.45896 -0.07994 0.01245  0.02501  214 GLU A OE2   
1740 O OE2   B GLU A 216 ? 0.47802 0.55087 0.43243 -0.09368 0.00926  0.02382  214 GLU A OE2   
1741 N N     . LEU A 217 ? 0.35977 0.35550 0.27744 -0.02074 0.01194  0.01134  215 LEU A N     
1742 C CA    . LEU A 217 ? 0.34570 0.34180 0.25788 -0.01182 0.00956  0.01173  215 LEU A CA    
1743 C C     . LEU A 217 ? 0.38752 0.40443 0.31307 -0.00038 0.00674  0.01509  215 LEU A C     
1744 O O     . LEU A 217 ? 0.36842 0.39479 0.29096 0.00618  -0.00044 0.01783  215 LEU A O     
1745 C CB    . LEU A 217 ? 0.35925 0.33285 0.26323 -0.00614 0.01727  0.01098  215 LEU A CB    
1746 C CG    . LEU A 217 ? 0.36997 0.32592 0.25670 -0.01065 0.01965  0.00514  215 LEU A CG    
1747 C CD1   . LEU A 217 ? 0.39835 0.34508 0.28703 -0.00407 0.02969  0.00312  215 LEU A CD1   
1748 C CD2   . LEU A 217 ? 0.39018 0.34737 0.25722 -0.01224 0.01479  0.00438  215 LEU A CD2   
1749 N N     . VAL A 218 ? 0.35868 0.38211 0.29628 0.00503  0.01111  0.01397  216 VAL A N     
1750 C CA    . VAL A 218 ? 0.35868 0.39849 0.30724 0.01960  0.00860  0.01314  216 VAL A CA    
1751 C C     . VAL A 218 ? 0.36574 0.44544 0.32678 0.01964  0.00299  0.01331  216 VAL A C     
1752 O O     . VAL A 218 ? 0.34719 0.44106 0.31366 0.03459  -0.00393 0.01380  216 VAL A O     
1753 C CB    . VAL A 218 ? 0.33992 0.37976 0.29480 0.02580  0.01409  0.00775  216 VAL A CB    
1754 C CG1   . VAL A 218 ? 0.35024 0.40649 0.31469 0.04379  0.01161  0.00268  216 VAL A CG1   
1755 C CG2   . VAL A 218 ? 0.37616 0.38475 0.32502 0.02504  0.01699  0.00590  216 VAL A CG2   
1756 N N     . ARG A 219 ? 0.33305 0.43227 0.29996 0.00280  0.00541  0.01364  217 ARG A N     
1757 C CA    . ARG A 219 ? 0.31323 0.45995 0.29824 -0.00261 0.00074  0.01327  217 ARG A CA    
1758 C C     . ARG A 219 ? 0.34075 0.49327 0.32214 -0.00331 -0.01226 0.01292  217 ARG A C     
1759 O O     . ARG A 219 ? 0.34201 0.53569 0.33965 0.00661  -0.02068 0.01172  217 ARG A O     
1760 C CB    . ARG A 219 ? 0.33503 0.49427 0.32483 -0.02762 0.00678  0.01608  217 ARG A CB    
1761 C CG    . ARG A 219 ? 0.38184 0.56106 0.37837 -0.02382 0.01863  0.01811  217 ARG A CG    
1762 C CD    . ARG A 219 ? 0.40254 0.60109 0.40416 -0.05067 0.02566  0.02551  217 ARG A CD    
1763 N NE    . ARG A 219 ? 0.49801 0.64369 0.47612 -0.06412 0.02781  0.03181  217 ARG A NE    
1764 C CZ    . ARG A 219 ? 0.43672 0.55877 0.39866 -0.05610 0.03436  0.03619  217 ARG A CZ    
1765 N NH1   . ARG A 219 ? 0.40164 0.54581 0.36584 -0.03763 0.03974  0.03303  217 ARG A NH1   
1766 N NH2   . ARG A 219 ? 0.43089 0.50609 0.37274 -0.06464 0.03393  0.04217  217 ARG A NH2   
1767 N N     . LEU A 220 ? 0.33279 0.44836 0.29179 -0.01238 -0.01466 0.01290  218 LEU A N     
1768 C CA    . LEU A 220 ? 0.37067 0.49229 0.31886 -0.01311 -0.02773 0.01146  218 LEU A CA    
1769 C C     . LEU A 220 ? 0.36886 0.49125 0.31133 0.01251  -0.03435 0.01729  218 LEU A C     
1770 O O     . LEU A 220 ? 0.40613 0.55731 0.35037 0.02007  -0.04852 0.01793  218 LEU A O     
1771 C CB    . LEU A 220 ? 0.38542 0.46610 0.30575 -0.02462 -0.02639 0.00795  218 LEU A CB    
1772 C CG    . LEU A 220 ? 0.42161 0.49179 0.34134 -0.04917 -0.02501 0.00110  218 LEU A CG    
1773 C CD1   . LEU A 220 ? 0.41650 0.43972 0.30777 -0.05079 -0.02069 -0.00446 218 LEU A CD1   
1774 C CD2   . LEU A 220 ? 0.39385 0.49942 0.32407 -0.06659 -0.03890 -0.00544 218 LEU A CD2   
1775 N N     . VAL A 221 ? 0.38228 0.47122 0.31684 0.02562  -0.02579 0.02198  219 VAL A N     
1776 C CA    . VAL A 221 ? 0.38354 0.45946 0.30897 0.04839  -0.03156 0.02989  219 VAL A CA    
1777 C C     . VAL A 221 ? 0.38908 0.50010 0.33894 0.06879  -0.03750 0.02750  219 VAL A C     
1778 O O     . VAL A 221 ? 0.41598 0.53769 0.36341 0.08935  -0.05017 0.03270  219 VAL A O     
1779 C CB    . VAL A 221 ? 0.40157 0.42869 0.31331 0.05051  -0.02040 0.03458  219 VAL A CB    
1780 C CG1   . VAL A 221 ? 0.46259 0.46613 0.36545 0.07218  -0.02565 0.04398  219 VAL A CG1   
1781 C CG2   . VAL A 221 ? 0.43850 0.44099 0.32699 0.03520  -0.01399 0.03703  219 VAL A CG2   
1782 N N     . LEU A 222 ? 0.35390 0.48536 0.32559 0.06644  -0.02853 0.01967  220 LEU A N     
1783 C CA    . LEU A 222 ? 0.36736 0.54223 0.36373 0.08737  -0.03163 0.01431  220 LEU A CA    
1784 C C     . LEU A 222 ? 0.37435 0.60857 0.38916 0.08762  -0.04437 0.01362  220 LEU A C     
1785 O O     . LEU A 222 ? 0.39764 0.66261 0.42625 0.11494  -0.05424 0.01262  220 LEU A O     
1786 C CB    . LEU A 222 ? 0.37080 0.56721 0.38358 0.08141  -0.01786 0.00604  220 LEU A CB    
1787 C CG    . LEU A 222 ? 0.40740 0.56301 0.40969 0.09225  -0.00963 0.00122  220 LEU A CG    
1788 C CD1   . LEU A 222 ? 0.45754 0.62455 0.46259 0.07587  0.00337  -0.00323 220 LEU A CD1   
1789 C CD2   . LEU A 222 ? 0.37968 0.54295 0.39040 0.12638  -0.01426 -0.00595 220 LEU A CD2   
1790 N N     . ALA A 223 ? 0.40158 0.65282 0.41792 0.05813  -0.04574 0.01265  221 ALA A N     
1791 C CA    . ALA A 223 ? 0.38161 0.69437 0.41911 0.05120  -0.05934 0.00917  221 ALA A CA    
1792 C C     . ALA A 223 ? 0.45120 0.76071 0.47077 0.06691  -0.07936 0.01377  221 ALA A C     
1793 O O     . ALA A 223 ? 0.43320 0.80254 0.47351 0.07189  -0.09526 0.01020  221 ALA A O     
1794 C CB    . ALA A 223 ? 0.36078 0.68078 0.40148 0.01111  -0.05581 0.00521  221 ALA A CB    
1795 N N     . GLU A 224 ? 0.44948 0.69592 0.43115 0.07438  -0.07911 0.02236  222 GLU A N     
1796 C CA    . GLU A 224 ? 0.47215 0.70893 0.42520 0.08460  -0.09619 0.02975  222 GLU A CA    
1797 C C     . GLU A 224 ? 0.48278 0.65904 0.40453 0.10793  -0.09318 0.04446  222 GLU A C     
1798 O O     . GLU A 224 ? 0.48524 0.61327 0.37270 0.09759  -0.08651 0.05160  222 GLU A O     
1799 C CB    . GLU A 224 ? 0.44811 0.67088 0.37766 0.05503  -0.09758 0.02457  222 GLU A CB    
1800 C CG    . GLU A 224 ? 0.51908 0.76339 0.42731 0.06001  -0.11999 0.02525  222 GLU A CG    
1801 C CD    . GLU A 224 ? 0.57743 0.81055 0.46287 0.03060  -0.12206 0.01370  222 GLU A CD    
1802 O OE1   . GLU A 224 ? 0.55508 0.77506 0.45173 0.00497  -0.10902 0.00388  222 GLU A OE1   
1803 O OE2   . GLU A 224 ? 0.63399 0.87097 0.48792 0.03482  -0.13816 0.01370  222 GLU A OE2   
1804 N N     . PRO A 225 ? 0.49959 0.67670 0.43193 0.13963  -0.09775 0.04916  223 PRO A N     
1805 C CA    . PRO A 225 ? 0.53931 0.65080 0.43960 0.16000  -0.09703 0.06514  223 PRO A CA    
1806 C C     . PRO A 225 ? 0.58484 0.67601 0.44261 0.16059  -0.10841 0.08076  223 PRO A C     
1807 O O     . PRO A 225 ? 0.63698 0.77285 0.49326 0.16847  -0.12780 0.08062  223 PRO A O     
1808 C CB    . PRO A 225 ? 0.56217 0.68923 0.48191 0.19917  -0.10740 0.06478  223 PRO A CB    
1809 C CG    . PRO A 225 ? 0.60191 0.80306 0.56849 0.19572  -0.10506 0.04620  223 PRO A CG    
1810 C CD    . PRO A 225 ? 0.54748 0.78829 0.51999 0.16017  -0.10577 0.04031  223 PRO A CD    
1811 N N     . GLY A 226 ? 0.62926 0.65751 0.45194 0.15134  -0.09619 0.09398  224 GLY A N     
1812 C CA    . GLY A 226 ? 0.69304 0.69934 0.46845 0.15029  -0.10210 0.11073  224 GLY A CA    
1813 C C     . GLY A 226 ? 0.66333 0.68525 0.42386 0.12123  -0.09614 0.10103  224 GLY A C     
1814 O O     . GLY A 226 ? 0.68808 0.69765 0.40517 0.12026  -0.10003 0.11216  224 GLY A O     
1815 N N     . ILE A 227 ? 0.59347 0.63848 0.38456 0.09911  -0.08668 0.08084  225 ILE A N     
1816 C CA    . ILE A 227 ? 0.63775 0.69057 0.41476 0.07427  -0.08226 0.06857  225 ILE A CA    
1817 C C     . ILE A 227 ? 0.54769 0.55511 0.28503 0.06715  -0.06596 0.07933  225 ILE A C     
1818 O O     . ILE A 227 ? 0.63023 0.60245 0.37109 0.06593  -0.04934 0.08806  225 ILE A O     
1819 C CB    . ILE A 227 ? 0.58648 0.65485 0.40031 0.05374  -0.07227 0.04984  225 ILE A CB    
1820 C CG1   . ILE A 227 ? 0.56737 0.63924 0.36605 0.03112  -0.07189 0.03483  225 ILE A CG1   
1821 C CG2   . ILE A 227 ? 0.53748 0.57074 0.36342 0.05112  -0.05185 0.05272  225 ILE A CG2   
1822 C CD1   . ILE A 227 ? 0.52255 0.60496 0.35170 0.01079  -0.06589 0.01929  225 ILE A CD1   
1823 N N     . GLY A 228 ? 0.61776 0.63013 0.31739 0.06137  -0.07040 0.07721  226 GLY A N     
1824 C CA    . GLY A 228 ? 0.69067 0.67083 0.35244 0.05421  -0.05206 0.08585  226 GLY A CA    
1825 C C     . GLY A 228 ? 0.60483 0.57535 0.28482 0.03586  -0.03100 0.07041  226 GLY A C     
1826 O O     . GLY A 228 ? 0.58618 0.57227 0.29495 0.02621  -0.03338 0.05098  226 GLY A O     
1827 N N     . ILE A 229 ? 0.65764 0.60306 0.32043 0.03093  -0.00982 0.08069  227 ILE A N     
1828 C CA    . ILE A 229 ? 0.67165 0.61271 0.35594 0.01819  0.00948  0.06718  227 ILE A CA    
1829 C C     . ILE A 229 ? 0.60720 0.56204 0.28230 0.01188  0.00745  0.04283  227 ILE A C     
1830 O O     . ILE A 229 ? 0.59730 0.55282 0.30079 0.00545  0.01050  0.02675  227 ILE A O     
1831 C CB    . ILE A 229 ? 0.75182 0.67487 0.42232 0.01248  0.03288  0.08194  227 ILE A CB    
1832 C CG1   . ILE A 229 ? 0.78525 0.71558 0.47945 0.00314  0.05056  0.06485  227 ILE A CG1   
1833 C CG2   . ILE A 229 ? 0.77740 0.69978 0.39290 0.01480  0.03713  0.09407  227 ILE A CG2   
1834 C CD1   . ILE A 229 ? 0.85103 0.77495 0.55351 -0.00610 0.07345  0.07693  227 ILE A CD1   
1835 N N     . ASP A 230 ? 0.64068 0.60236 0.27242 0.01439  0.00124  0.03935  228 ASP A N     
1836 C CA    . ASP A 230 ? 0.64538 0.61231 0.26452 0.00859  -0.00200 0.01221  228 ASP A CA    
1837 C C     . ASP A 230 ? 0.63931 0.61841 0.28443 0.00151  -0.02389 -0.00304 228 ASP A C     
1838 O O     . ASP A 230 ? 0.64323 0.61373 0.30287 -0.00795 -0.02299 -0.02297 228 ASP A O     
1839 C CB    . ASP A 230 ? 0.73326 0.70543 0.29450 0.01326  -0.00336 0.00902  228 ASP A CB    
1840 C CG    . ASP A 230 ? 0.68706 0.67211 0.22955 0.01980  -0.02081 0.02898  228 ASP A CG    
1841 O OD1   . ASP A 230 ? 0.78940 0.77540 0.35260 0.02675  -0.03208 0.04449  228 ASP A OD1   
1842 O OD2   . ASP A 230 ? 0.76631 0.75908 0.27438 0.01888  -0.02365 0.02837  228 ASP A OD2   
1843 N N     . GLU A 231 ? 0.59900 0.59862 0.25178 0.00605  -0.04318 0.00714  229 GLU A N     
1844 C CA    . GLU A 231 ? 0.61075 0.63311 0.29716 -0.00341 -0.06123 -0.00511 229 GLU A CA    
1845 C C     . GLU A 231 ? 0.61575 0.62953 0.34668 -0.01135 -0.05001 -0.00697 229 GLU A C     
1846 O O     . GLU A 231 ? 0.54387 0.56228 0.29474 -0.02667 -0.05574 -0.02162 229 GLU A O     
1847 C CB    . GLU A 231 ? 0.58844 0.64289 0.28279 0.00847  -0.08125 0.00814  229 GLU A CB    
1848 C CG    . GLU A 231 ? 0.63508 0.72712 0.36887 -0.00246 -0.09839 -0.00408 229 GLU A CG    
1849 C CD    . GLU A 231 ? 0.74011 0.87371 0.48309 0.01427  -0.11962 0.00656  229 GLU A CD    
1850 O OE1   . GLU A 231 ? 0.78677 0.91317 0.49465 0.03430  -0.12506 0.02266  229 GLU A OE1   
1851 O OE2   . GLU A 231 ? 0.77275 0.94722 0.55802 0.00839  -0.13005 0.00012  229 GLU A OE2   
1852 N N     . LEU A 232 ? 0.50157 0.50202 0.24678 -0.00268 -0.03497 0.00833  230 LEU A N     
1853 C CA    . LEU A 232 ? 0.50739 0.50141 0.28879 -0.00839 -0.02534 0.00596  230 LEU A CA    
1854 C C     . LEU A 232 ? 0.46453 0.43677 0.24128 -0.01813 -0.01583 -0.00948 230 LEU A C     
1855 O O     . LEU A 232 ? 0.46336 0.43235 0.26097 -0.02821 -0.01717 -0.01681 230 LEU A O     
1856 C CB    . LEU A 232 ? 0.47154 0.45373 0.26468 0.00191  -0.01285 0.02154  230 LEU A CB    
1857 C CG    . LEU A 232 ? 0.46738 0.44565 0.29361 -0.00095 -0.00414 0.01947  230 LEU A CG    
1858 C CD1   . LEU A 232 ? 0.43535 0.43924 0.28822 -0.00374 -0.01469 0.01637  230 LEU A CD1   
1859 C CD2   . LEU A 232 ? 0.49881 0.46315 0.33111 0.00720  0.00552  0.03157  230 LEU A CD2   
1860 N N     . ALA A 233 ? 0.51093 0.46770 0.25826 -0.01383 -0.00579 -0.01407 231 ALA A N     
1861 C CA    . ALA A 233 ? 0.54934 0.48447 0.29038 -0.01674 0.00221  -0.03129 231 ALA A CA    
1862 C C     . ALA A 233 ? 0.53422 0.46136 0.26582 -0.02939 -0.01325 -0.05010 231 ALA A C     
1863 O O     . ALA A 233 ? 0.60085 0.50453 0.34225 -0.03615 -0.01242 -0.06047 231 ALA A O     
1864 C CB    . ALA A 233 ? 0.54696 0.47677 0.25791 -0.00705 0.01732  -0.03447 231 ALA A CB    
1865 N N     . GLU A 234 ? 0.56666 0.51094 0.27780 -0.03343 -0.02880 -0.05440 232 GLU A N     
1866 C CA    . GLU A 234 ? 0.59394 0.53436 0.29824 -0.05034 -0.04633 -0.07456 232 GLU A CA    
1867 C C     . GLU A 234 ? 0.59262 0.54039 0.33756 -0.06756 -0.05286 -0.07091 232 GLU A C     
1868 O O     . GLU A 234 ? 0.60298 0.52514 0.35092 -0.08456 -0.05672 -0.08458 232 GLU A O     
1869 C CB    . GLU A 234 ? 0.64986 0.61943 0.32868 -0.05032 -0.06482 -0.07802 232 GLU A CB    
1870 C CG    . GLU A 234 ? 0.68989 0.64789 0.31716 -0.03848 -0.05969 -0.08798 232 GLU A CG    
1871 C CD    . GLU A 234 ? 0.87396 0.85757 0.46858 -0.04048 -0.08245 -0.09695 232 GLU A CD    
1872 O OE1   . GLU A 234 ? 0.91510 0.93143 0.53349 -0.04912 -0.10267 -0.09297 232 GLU A OE1   
1873 O OE2   . GLU A 234 ? 0.94772 0.92503 0.49633 -0.03107 -0.07996 -0.10814 232 GLU A OE2   
1874 N N     . ARG A 235 ? 0.52676 0.50665 0.30113 -0.06309 -0.05284 -0.05217 233 ARG A N     
1875 C CA    . ARG A 235 ? 0.49541 0.49301 0.30759 -0.07859 -0.05635 -0.04785 233 ARG A CA    
1876 C C     . ARG A 235 ? 0.57947 0.54392 0.40334 -0.08111 -0.04118 -0.04407 233 ARG A C     
1877 O O     . ARG A 235 ? 0.55777 0.51522 0.39660 -0.10081 -0.04307 -0.04586 233 ARG A O     
1878 C CB    . ARG A 235 ? 0.51971 0.56267 0.35739 -0.06727 -0.05975 -0.03201 233 ARG A CB    
1879 C CG    . ARG A 235 ? 0.54788 0.62873 0.37768 -0.06336 -0.07913 -0.03431 233 ARG A CG    
1880 C CD    . ARG A 235 ? 0.63723 0.76756 0.50101 -0.05336 -0.08555 -0.02268 233 ARG A CD    
1881 N NE    . ARG A 235 ? 0.64132 0.81192 0.49837 -0.04583 -0.10736 -0.02458 233 ARG A NE    
1882 C CZ    . ARG A 235 ? 0.72333 0.93604 0.59619 -0.06447 -0.12579 -0.03777 233 ARG A CZ    
1883 N NH1   . ARG A 235 ? 0.74979 0.96570 0.64635 -0.09511 -0.12332 -0.04853 233 ARG A NH1   
1884 N NH2   . ARG A 235 ? 0.63834 0.89116 0.50281 -0.05321 -0.14809 -0.03921 233 ARG A NH2   
1885 N N     . LEU A 236 ? 0.50647 0.45196 0.32360 -0.06254 -0.02653 -0.03764 234 LEU A N     
1886 C CA    . LEU A 236 ? 0.55389 0.47009 0.37895 -0.06135 -0.01533 -0.03536 234 LEU A CA    
1887 C C     . LEU A 236 ? 0.59482 0.46719 0.39968 -0.07022 -0.01796 -0.05117 234 LEU A C     
1888 O O     . LEU A 236 ? 0.53993 0.38748 0.35195 -0.08129 -0.01766 -0.04902 234 LEU A O     
1889 C CB    . LEU A 236 ? 0.48414 0.39672 0.30928 -0.04073 -0.00138 -0.02847 234 LEU A CB    
1890 C CG    . LEU A 236 ? 0.51424 0.40295 0.34751 -0.03525 0.00721  -0.02695 234 LEU A CG    
1891 C CD1   . LEU A 236 ? 0.49107 0.39049 0.34644 -0.04421 0.00561  -0.01544 234 LEU A CD1   
1892 C CD2   . LEU A 236 ? 0.48371 0.37801 0.32150 -0.01767 0.01917  -0.02362 234 LEU A CD2   
1893 N N     . ASP A 237 ? 0.53417 0.39274 0.30961 -0.06482 -0.02059 -0.06725 235 ASP A N     
1894 C CA    . ASP A 237 ? 0.57563 0.38612 0.32833 -0.07035 -0.02428 -0.08691 235 ASP A CA    
1895 C C     . ASP A 237 ? 0.61116 0.41152 0.37005 -0.10085 -0.03921 -0.09268 235 ASP A C     
1896 O O     . ASP A 237 ? 0.68096 0.43198 0.43363 -0.11153 -0.04072 -0.09899 235 ASP A O     
1897 C CB    . ASP A 237 ? 0.61407 0.41815 0.33025 -0.05851 -0.02464 -0.10662 235 ASP A CB    
1898 C CG    . ASP A 237 ? 0.66077 0.46071 0.36853 -0.03135 -0.00620 -0.10656 235 ASP A CG    
1899 O OD1   . ASP A 237 ? 0.67844 0.47402 0.40890 -0.02201 0.00368  -0.09461 235 ASP A OD1   
1900 O OD2   . ASP A 237 ? 0.69126 0.49641 0.36897 -0.01991 -0.00174 -0.11954 235 ASP A OD2   
1901 N N     . ALA A 238 ? 0.61496 0.46136 0.38632 -0.11560 -0.05105 -0.09056 236 ALA A N     
1902 C CA    . ALA A 238 ? 0.67791 0.52747 0.46293 -0.14915 -0.06486 -0.09623 236 ALA A CA    
1903 C C     . ALA A 238 ? 0.65705 0.49995 0.46967 -0.16282 -0.05619 -0.07753 236 ALA A C     
1904 O O     . ALA A 238 ? 0.70982 0.51647 0.52202 -0.18913 -0.05994 -0.08099 236 ALA A O     
1905 C CB    . ALA A 238 ? 0.63171 0.54651 0.43140 -0.15766 -0.07970 -0.09669 236 ALA A CB    
1906 N N     . PHE A 239 ? 0.60146 0.47475 0.43425 -0.14592 -0.04434 -0.05757 237 PHE A N     
1907 C CA    . PHE A 239 ? 0.64167 0.51155 0.49401 -0.15589 -0.03501 -0.03963 237 PHE A CA    
1908 C C     . PHE A 239 ? 0.69518 0.49374 0.52551 -0.15287 -0.02926 -0.03961 237 PHE A C     
1909 O O     . PHE A 239 ? 0.75255 0.52065 0.58342 -0.17583 -0.02896 -0.03209 237 PHE A O     
1910 C CB    . PHE A 239 ? 0.56267 0.47289 0.43396 -0.13373 -0.02436 -0.02324 237 PHE A CB    
1911 C CG    . PHE A 239 ? 0.67417 0.58127 0.55753 -0.13902 -0.01376 -0.00576 237 PHE A CG    
1912 C CD1   . PHE A 239 ? 0.65350 0.51229 0.52021 -0.12722 -0.00650 0.00014  237 PHE A CD1   
1913 C CD2   . PHE A 239 ? 0.70043 0.65852 0.61064 -0.15307 -0.01112 0.00472  237 PHE A CD2   
1914 C CE1   . PHE A 239 ? 0.76745 0.62363 0.63856 -0.13143 0.00164  0.01778  237 PHE A CE1   
1915 C CE2   . PHE A 239 ? 0.62027 0.57882 0.53564 -0.15777 0.00018  0.02128  237 PHE A CE2   
1916 C CZ    . PHE A 239 ? 0.70237 0.60799 0.59553 -0.14702 0.00595  0.02867  237 PHE A CZ    
1917 N N     . GLU A 240 ? 0.64155 0.41382 0.45241 -0.12378 -0.02427 -0.04679 238 GLU A N     
1918 C CA    . GLU A 240 ? 0.68406 0.39335 0.47562 -0.11173 -0.01991 -0.04784 238 GLU A CA    
1919 C C     . GLU A 240 ? 0.79873 0.44631 0.56812 -0.13259 -0.02986 -0.06283 238 GLU A C     
1920 O O     . GLU A 240 ? 0.85943 0.45226 0.61948 -0.13948 -0.02916 -0.05427 238 GLU A O     
1921 C CB    . GLU A 240 ? 0.66062 0.36849 0.44083 -0.07672 -0.01276 -0.05699 238 GLU A CB    
1922 C CG    . GLU A 240 ? 0.66539 0.42152 0.46762 -0.05929 -0.00305 -0.04159 238 GLU A CG    
1923 C CD    . GLU A 240 ? 0.66847 0.41741 0.48215 -0.05687 0.00128  -0.02267 238 GLU A CD    
1924 O OE1   . GLU A 240 ? 0.67221 0.38026 0.47375 -0.04182 0.00255  -0.02265 238 GLU A OE1   
1925 O OE2   . GLU A 240 ? 0.67314 0.45824 0.50552 -0.06739 0.00291  -0.00847 238 GLU A OE2   
1926 N N     . ARG A 241 ? 0.77659 0.42763 0.53381 -0.14302 -0.04045 -0.08537 239 ARG A N     
1927 C CA    . ARG A 241 ? 0.82440 0.41150 0.55819 -0.16408 -0.05190 -0.10491 239 ARG A CA    
1928 C C     . ARG A 241 ? 0.84324 0.43286 0.59816 -0.20675 -0.05761 -0.09258 239 ARG A C     
1929 O O     . ARG A 241 ? 0.84833 0.38859 0.60080 -0.21662 -0.05885 -0.09041 239 ARG A O     
1930 C CB    . ARG A 241 ? 0.82652 0.42442 0.53938 -0.16161 -0.06252 -0.13457 239 ARG A CB    
1931 C CG    . ARG A 241 ? 0.92452 0.50438 0.61116 -0.12071 -0.05350 -0.14853 239 ARG A CG    
1932 C CD    . ARG A 241 ? 0.98455 0.57284 0.65015 -0.11322 -0.06096 -0.17668 239 ARG A CD    
1933 N NE    . ARG A 241 ? 1.12559 0.69272 0.77207 -0.07558 -0.04925 -0.18978 239 ARG A NE    
1934 C CZ    . ARG A 241 ? 1.10351 0.70798 0.73607 -0.05136 -0.03934 -0.19516 239 ARG A CZ    
1935 N NH1   . ARG A 241 ? 0.97586 0.63220 0.60643 -0.05808 -0.04038 -0.18631 239 ARG A NH1   
1936 N NH2   . ARG A 241 ? 1.15487 0.74829 0.77741 -0.01961 -0.02710 -0.20752 239 ARG A NH2   
1937 N N     . ASP A 242 ? 0.77193 0.43446 0.55719 -0.22510 -0.05846 -0.08129 240 ASP A N     
1938 C CA    . ASP A 242 ? 0.86376 0.54742 0.67669 -0.26427 -0.05967 -0.06739 240 ASP A CA    
1939 C C     . ASP A 242 ? 0.83468 0.48527 0.64901 -0.26464 -0.04553 -0.03962 240 ASP A C     
1940 O O     . ASP A 242 ? 0.82595 0.46620 0.65237 -0.28991 -0.04369 -0.02822 240 ASP A O     
1941 C CB    . ASP A 242 ? 0.84082 0.62069 0.68882 -0.27362 -0.06181 -0.06178 240 ASP A CB    
1942 C CG    . ASP A 242 ? 1.00518 0.82674 0.88840 -0.31198 -0.06314 -0.05273 240 ASP A CG    
1943 O OD1   . ASP A 242 ? 1.03582 0.81937 0.92015 -0.32739 -0.05492 -0.03864 240 ASP A OD1   
1944 O OD2   . ASP A 242 ? 1.04073 0.93837 0.95215 -0.32131 -0.07194 -0.05893 240 ASP A OD2   
1945 N N     . ALA A 243 ? 0.79595 0.43587 0.59934 -0.23268 -0.03524 -0.02788 241 ALA A N     
1946 C CA    . ALA A 243 ? 0.90678 0.50963 0.70190 -0.22773 -0.02451 -0.00236 241 ALA A CA    
1947 C C     . ALA A 243 ? 0.92520 0.44671 0.69249 -0.20699 -0.02721 -0.00741 241 ALA A C     
1948 O O     . ALA A 243 ? 0.98374 0.47453 0.74252 -0.19577 -0.02094 0.01357  241 ALA A O     
1949 C CB    . ALA A 243 ? 0.79646 0.44828 0.60319 -0.19244 -0.01361 0.01123  241 ALA A CB    
1950 N N     . GLY A 244 ? 0.89179 0.38274 0.64476 -0.19905 -0.03676 -0.03511 242 GLY A N     
1951 C CA    . GLY A 244 ? 0.92440 0.34399 0.65490 -0.17749 -0.03964 -0.04370 242 GLY A CA    
1952 C C     . GLY A 244 ? 1.00363 0.40859 0.71718 -0.13053 -0.03627 -0.05433 242 GLY A C     
1953 O O     . GLY A 244 ? 1.12424 0.47843 0.82242 -0.10779 -0.03869 -0.06453 242 GLY A O     
1954 N N     . ARG A 245 ? 0.97000 0.42064 0.68851 -0.11506 -0.03015 -0.05301 243 ARG A N     
1955 C CA    . ARG A 245 ? 0.94342 0.39360 0.65232 -0.07134 -0.02462 -0.06313 243 ARG A CA    
1956 C C     . ARG A 245 ? 1.00018 0.47035 0.69959 -0.06203 -0.02623 -0.09340 243 ARG A C     
1957 O O     . ARG A 245 ? 1.00969 0.50020 0.70924 -0.08849 -0.03337 -0.10474 243 ARG A O     
1958 C CB    . ARG A 245 ? 0.87124 0.38586 0.60561 -0.05585 -0.01482 -0.04194 243 ARG A CB    
1959 C CG    . ARG A 245 ? 0.85671 0.34319 0.58825 -0.04896 -0.01310 -0.01601 243 ARG A CG    
1960 C CD    . ARG A 245 ? 0.79200 0.34372 0.54773 -0.04660 -0.00592 0.00573  243 ARG A CD    
1961 N NE    . ARG A 245 ? 0.69025 0.31010 0.47010 -0.06634 -0.00270 0.00527  243 ARG A NE    
1962 C CZ    . ARG A 245 ? 0.74573 0.39524 0.53846 -0.09192 -0.00014 0.02192  243 ARG A CZ    
1963 N NH1   . ARG A 245 ? 0.81145 0.42756 0.59281 -0.10829 0.00099  0.04188  243 ARG A NH1   
1964 N NH2   . ARG A 245 ? 0.74747 0.46176 0.56366 -0.10030 0.00204  0.01930  243 ARG A NH2   
1965 N N     . LYS A 246 ? 0.96926 0.44192 0.66197 -0.02305 -0.01937 -0.10581 244 LYS A N     
1966 C CA    . LYS A 246 ? 0.92212 0.41714 0.60317 -0.01060 -0.01755 -0.13247 244 LYS A CA    
1967 C C     . LYS A 246 ? 0.85393 0.42420 0.54936 -0.00830 -0.00903 -0.12657 244 LYS A C     
1968 O O     . LYS A 246 ? 0.79191 0.40393 0.51503 -0.01309 -0.00469 -0.10270 244 LYS A O     
1969 C CB    . LYS A 246 ? 1.02477 0.50388 0.70140 0.02830  -0.01157 -0.14674 244 LYS A CB    
1970 N N     . GLY A 247 ? 0.89039 0.48223 0.56810 -0.00060 -0.00649 -0.14686 245 GLY A N     
1971 C CA    . GLY A 247 ? 0.79822 0.45951 0.48853 0.00037  0.00133  -0.13720 245 GLY A CA    
1972 C C     . GLY A 247 ? 0.70615 0.40236 0.41983 0.02435  0.01701  -0.12302 245 GLY A C     
1973 O O     . GLY A 247 ? 0.76147 0.43944 0.47544 0.04947  0.02376  -0.12968 245 GLY A O     
1974 N N     . VAL A 248 ? 0.62881 0.37632 0.36358 0.01699  0.02150  -0.10440 246 VAL A N     
1975 C CA    . VAL A 248 ? 0.58509 0.36768 0.34556 0.03281  0.03445  -0.09127 246 VAL A CA    
1976 C C     . VAL A 248 ? 0.66956 0.47993 0.41949 0.04908  0.04931  -0.10176 246 VAL A C     
1977 O O     . VAL A 248 ? 0.63269 0.45833 0.36158 0.04170  0.05063  -0.10533 246 VAL A O     
1978 C CB    . VAL A 248 ? 0.54807 0.36603 0.33319 0.01812  0.03302  -0.06922 246 VAL A CB    
1979 C CG1   . VAL A 248 ? 0.56618 0.41435 0.37814 0.03137  0.04399  -0.05909 246 VAL A CG1   
1980 C CG2   . VAL A 248 ? 0.59238 0.39226 0.38635 0.00063  0.02115  -0.05941 246 VAL A CG2   
1981 N N     . ASP A 249 ? 0.60299 0.42523 0.36733 0.07154  0.06080  -0.10572 247 ASP A N     
1982 C CA    . ASP A 249 ? 0.62539 0.48141 0.38183 0.08561  0.07842  -0.11603 247 ASP A CA    
1983 C C     . ASP A 249 ? 0.48036 0.38301 0.25027 0.07110  0.08818  -0.09665 247 ASP A C     
1984 O O     . ASP A 249 ? 0.49872 0.41109 0.29381 0.05846  0.08290  -0.07795 247 ASP A O     
1985 C CB    . ASP A 249 ? 0.61209 0.47935 0.38683 0.11467  0.08848  -0.12660 247 ASP A CB    
1986 C CG    . ASP A 249 ? 0.68979 0.58990 0.50754 0.11520  0.08985  -0.10908 247 ASP A CG    
1987 O OD1   . ASP A 249 ? 0.76684 0.64022 0.59491 0.11443  0.07588  -0.10052 247 ASP A OD1   
1988 O OD2   . ASP A 249 ? 0.75506 0.70789 0.59446 0.11428  0.10485  -0.10377 247 ASP A OD2   
1989 N N     . ALA A 250 ? 0.57375 0.50136 0.32221 0.07325  0.10281  -0.10138 248 ALA A N     
1990 C CA    . ALA A 250 ? 0.56399 0.52203 0.31383 0.05701  0.11087  -0.08049 248 ALA A CA    
1991 C C     . ALA A 250 ? 0.48535 0.47452 0.27912 0.05310  0.12005  -0.06507 248 ALA A C     
1992 O O     . ALA A 250 ? 0.47873 0.47130 0.28413 0.03676  0.11623  -0.04568 248 ALA A O     
1993 C CB    . ALA A 250 ? 0.56092 0.53978 0.27453 0.06081  0.12752  -0.08642 248 ALA A CB    
1994 N N     . ALA A 251 ? 0.51069 0.52386 0.32984 0.06906  0.13088  -0.07531 249 ALA A N     
1995 C CA    . ALA A 251 ? 0.49400 0.54213 0.35792 0.06320  0.13676  -0.06394 249 ALA A CA    
1996 C C     . ALA A 251 ? 0.49408 0.52027 0.37787 0.05537  0.11732  -0.05387 249 ALA A C     
1997 O O     . ALA A 251 ? 0.46686 0.50703 0.37245 0.03987  0.11711  -0.03995 249 ALA A O     
1998 C CB    . ALA A 251 ? 0.45032 0.53490 0.34116 0.08553  0.14805  -0.07946 249 ALA A CB    
1999 N N     . THR A 252 ? 0.46651 0.45598 0.34047 0.06478  0.10152  -0.06087 250 THR A N     
2000 C CA    . THR A 252 ? 0.46938 0.44308 0.35889 0.05818  0.08586  -0.05081 250 THR A CA    
2001 C C     . THR A 252 ? 0.41892 0.38173 0.29840 0.03785  0.07919  -0.03718 250 THR A C     
2002 O O     . THR A 252 ? 0.38435 0.35596 0.28339 0.02910  0.07501  -0.02664 250 THR A O     
2003 C CB    . THR A 252 ? 0.46467 0.39929 0.34221 0.07069  0.07321  -0.05836 250 THR A CB    
2004 O OG1   . THR A 252 ? 0.47573 0.41930 0.36365 0.09593  0.07779  -0.07067 250 THR A OG1   
2005 C CG2   . THR A 252 ? 0.45764 0.37880 0.34571 0.06221  0.05944  -0.04548 250 THR A CG2   
2006 N N     . PHE A 253 ? 0.42460 0.37085 0.27311 0.03239  0.07729  -0.03915 251 PHE A N     
2007 C CA    . PHE A 253 ? 0.46008 0.40223 0.29997 0.01793  0.06962  -0.02657 251 PHE A CA    
2008 C C     . PHE A 253 ? 0.41135 0.37337 0.26310 0.01049  0.07870  -0.01252 251 PHE A C     
2009 O O     . PHE A 253 ? 0.43081 0.39087 0.29657 0.00395  0.07182  -0.00223 251 PHE A O     
2010 C CB    . PHE A 253 ? 0.46206 0.39169 0.26592 0.01521  0.06502  -0.03263 251 PHE A CB    
2011 C CG    . PHE A 253 ? 0.50030 0.43348 0.29500 0.00535  0.05646  -0.01925 251 PHE A CG    
2012 C CD1   . PHE A 253 ? 0.52093 0.44963 0.32662 -0.00115 0.04138  -0.01538 251 PHE A CD1   
2013 C CD2   . PHE A 253 ? 0.53492 0.47812 0.31022 0.00404  0.06408  -0.00887 251 PHE A CD2   
2014 C CE1   . PHE A 253 ? 0.47816 0.41553 0.27862 -0.00480 0.03236  -0.00449 251 PHE A CE1   
2015 C CE2   . PHE A 253 ? 0.53317 0.47612 0.29831 0.00011  0.05377  0.00500  251 PHE A CE2   
2016 C CZ    . PHE A 253 ? 0.44845 0.39024 0.22855 -0.00231 0.03719  0.00584  251 PHE A CZ    
2017 N N     . THR A 254 ? 0.43014 0.40998 0.27570 0.01086  0.09520  -0.01232 252 THR A N     
2018 C CA    . THR A 254 ? 0.44333 0.43401 0.29527 -0.00152 0.10481  0.00400  252 THR A CA    
2019 C C     . THR A 254 ? 0.44016 0.44311 0.33265 -0.00680 0.10477  0.00565  252 THR A C     
2020 O O     . THR A 254 ? 0.42373 0.41765 0.32416 -0.01806 0.10227  0.01760  252 THR A O     
2021 C CB    . THR A 254 ? 0.53090 0.54192 0.36495 -0.00363 0.12564  0.00607  252 THR A CB    
2022 O OG1   . THR A 254 ? 0.53411 0.57516 0.38992 0.00547  0.13826  -0.00858 252 THR A OG1   
2023 C CG2   . THR A 254 ? 0.51495 0.51418 0.30249 0.00260  0.12345  0.00195  252 THR A CG2   
2024 N N     . SER A 255 ? 0.40606 0.42669 0.32241 0.00312  0.10502  -0.00750 253 SER A N     
2025 C CA    . SER A 255 ? 0.39430 0.43235 0.34784 -0.00102 0.10187  -0.00850 253 SER A CA    
2026 C C     . SER A 255 ? 0.39021 0.40528 0.34590 -0.00237 0.08459  -0.00514 253 SER A C     
2027 O O     . SER A 255 ? 0.36058 0.37591 0.33244 -0.01265 0.08157  -0.00115 253 SER A O     
2028 C CB    . SER A 255 ? 0.37694 0.44267 0.35254 0.01519  0.10339  -0.02284 253 SER A CB    
2029 O OG    . SER A 255 ? 0.38584 0.47082 0.39473 0.01305  0.09543  -0.02534 253 SER A OG    
2030 N N     . ILE A 256 ? 0.34418 0.33940 0.28323 0.00678  0.07386  -0.00778 254 ILE A N     
2031 C CA    . ILE A 256 ? 0.35033 0.33225 0.29119 0.00570  0.06065  -0.00445 254 ILE A CA    
2032 C C     . ILE A 256 ? 0.39777 0.36793 0.33074 -0.00291 0.05894  0.00534  254 ILE A C     
2033 O O     . ILE A 256 ? 0.35515 0.32266 0.29979 -0.00508 0.05339  0.00656  254 ILE A O     
2034 C CB    . ILE A 256 ? 0.35107 0.31647 0.27604 0.01191  0.05225  -0.00693 254 ILE A CB    
2035 C CG1   . ILE A 256 ? 0.35747 0.32386 0.28839 0.02416  0.05118  -0.01431 254 ILE A CG1   
2036 C CG2   . ILE A 256 ? 0.37441 0.33520 0.30107 0.00862  0.04236  -0.00191 254 ILE A CG2   
2037 C CD1   . ILE A 256 ? 0.39575 0.33416 0.30635 0.02748  0.04494  -0.01613 254 ILE A CD1   
2038 N N     . VAL A 257 ? 0.38900 0.35049 0.29913 -0.00527 0.06266  0.01163  255 VAL A N     
2039 C CA    . VAL A 257 ? 0.38286 0.33006 0.28210 -0.00849 0.05861  0.02321  255 VAL A CA    
2040 C C     . VAL A 257 ? 0.38150 0.32276 0.29356 -0.01759 0.06531  0.02971  255 VAL A C     
2041 O O     . VAL A 257 ? 0.41645 0.34069 0.33205 -0.01719 0.05830  0.03387  255 VAL A O     
2042 C CB    . VAL A 257 ? 0.44373 0.38523 0.31130 -0.00766 0.05945  0.02963  255 VAL A CB    
2043 C CG1   . VAL A 257 ? 0.49987 0.42461 0.35391 -0.00813 0.05621  0.04547  255 VAL A CG1   
2044 C CG2   . VAL A 257 ? 0.43104 0.37472 0.28949 -0.00293 0.04783  0.02165  255 VAL A CG2   
2045 N N     . ALA A 258 ? 0.37342 0.32928 0.29451 -0.02631 0.07907  0.02906  256 ALA A N     
2046 C CA    . ALA A 258 ? 0.39131 0.34317 0.32892 -0.04168 0.08599  0.03461  256 ALA A CA    
2047 C C     . ALA A 258 ? 0.37237 0.32395 0.33625 -0.04170 0.07494  0.02349  256 ALA A C     
2048 O O     . ALA A 258 ? 0.38768 0.31595 0.35638 -0.05035 0.07161  0.02654  256 ALA A O     
2049 C CB    . ALA A 258 ? 0.44013 0.42307 0.39095 -0.05248 0.10399  0.03335  256 ALA A CB    
2050 N N     . ASP A 259 ? 0.33878 0.31210 0.31552 -0.03112 0.06853  0.01040  257 ASP A N     
2051 C CA    . ASP A 259 ? 0.36517 0.34308 0.36044 -0.02879 0.05735  -0.00082 257 ASP A CA    
2052 C C     . ASP A 259 ? 0.35278 0.30426 0.33456 -0.02169 0.04713  0.00088  257 ASP A C     
2053 O O     . ASP A 259 ? 0.37201 0.31091 0.36188 -0.02459 0.04109  -0.00550 257 ASP A O     
2054 C CB    . ASP A 259 ? 0.33795 0.33954 0.33926 -0.01547 0.05226  -0.00988 257 ASP A CB    
2055 C CG    . ASP A 259 ? 0.37972 0.41604 0.40554 -0.01693 0.05774  -0.01744 257 ASP A CG    
2056 O OD1   . ASP A 259 ? 0.40184 0.45150 0.44393 -0.03216 0.06770  -0.01639 257 ASP A OD1   
2057 O OD2   . ASP A 259 ? 0.37038 0.42201 0.39927 -0.00219 0.05249  -0.02333 257 ASP A OD2   
2058 N N     . LEU A 260 ? 0.33121 0.27674 0.29358 -0.01167 0.04457  0.00713  258 LEU A N     
2059 C CA    . LEU A 260 ? 0.37113 0.30510 0.32617 -0.00159 0.03542  0.00718  258 LEU A CA    
2060 C C     . LEU A 260 ? 0.38573 0.28870 0.33387 -0.00260 0.03437  0.01426  258 LEU A C     
2061 O O     . LEU A 260 ? 0.38481 0.27445 0.33517 0.00607  0.02707  0.00814  258 LEU A O     
2062 C CB    . LEU A 260 ? 0.38641 0.32932 0.32773 0.00561  0.03250  0.01180  258 LEU A CB    
2063 C CG    . LEU A 260 ? 0.37232 0.33334 0.31653 0.00668  0.03175  0.00626  258 LEU A CG    
2064 C CD1   . LEU A 260 ? 0.33866 0.30313 0.26960 0.00678  0.02894  0.01033  258 LEU A CD1   
2065 C CD2   . LEU A 260 ? 0.32227 0.29454 0.27605 0.01201  0.02692  -0.00129 258 LEU A CD2   
2066 N N     . VAL A 261 ? 0.37594 0.26422 0.31226 -0.01154 0.04198  0.02754  259 VAL A N     
2067 C CA    . VAL A 261 ? 0.38848 0.23744 0.31396 -0.01398 0.04134  0.03854  259 VAL A CA    
2068 C C     . VAL A 261 ? 0.41377 0.24576 0.35788 -0.02751 0.04202  0.02947  259 VAL A C     
2069 O O     . VAL A 261 ? 0.45854 0.25467 0.39966 -0.02233 0.03450  0.02681  259 VAL A O     
2070 C CB    . VAL A 261 ? 0.46463 0.30284 0.36742 -0.02260 0.05119  0.05819  259 VAL A CB    
2071 C CG1   . VAL A 261 ? 0.48235 0.27137 0.36995 -0.02705 0.05113  0.07409  259 VAL A CG1   
2072 C CG2   . VAL A 261 ? 0.48971 0.34328 0.37137 -0.00868 0.04616  0.06332  259 VAL A CG2   
2073 N N     . ALA A 262 ? 0.39241 0.25111 0.35725 -0.04378 0.04949  0.02206  260 ALA A N     
2074 C CA    . ALA A 262 ? 0.41135 0.26106 0.39777 -0.06107 0.04833  0.01114  260 ALA A CA    
2075 C C     . ALA A 262 ? 0.39207 0.23810 0.38470 -0.04796 0.03386  -0.00895 260 ALA A C     
2076 O O     . ALA A 262 ? 0.44095 0.25565 0.43828 -0.05557 0.02784  -0.01858 260 ALA A O     
2077 C CB    . ALA A 262 ? 0.39349 0.28801 0.40646 -0.07763 0.05720  0.00497  260 ALA A CB    
2078 N N     . GLU A 263 ? 0.37108 0.24630 0.36080 -0.02907 0.02877  -0.01559 261 GLU A N     
2079 C CA    . GLU A 263 ? 0.40176 0.28197 0.39316 -0.01565 0.01780  -0.03380 261 GLU A CA    
2080 C C     . GLU A 263 ? 0.43776 0.28703 0.41312 0.00253  0.01207  -0.03425 261 GLU A C     
2081 O O     . GLU A 263 ? 0.45638 0.30237 0.43116 0.01371  0.00436  -0.05210 261 GLU A O     
2082 C CB    . GLU A 263 ? 0.35470 0.27691 0.34658 -0.00481 0.01668  -0.03689 261 GLU A CB    
2083 C CG    . GLU A 263 ? 0.39129 0.34392 0.40034 -0.01562 0.01896  -0.04015 261 GLU A CG    
2084 C CD    . GLU A 263 ? 0.39460 0.37667 0.39907 -0.00326 0.01687  -0.03989 261 GLU A CD    
2085 O OE1   . GLU A 263 ? 0.37671 0.36054 0.36768 0.00920  0.01275  -0.04144 261 GLU A OE1   
2086 O OE2   . GLU A 263 ? 0.35755 0.36047 0.37139 -0.00542 0.02002  -0.03760 261 GLU A OE2   
2087 N N     . GLY A 264 ? 0.45014 0.27925 0.41141 0.00825  0.01491  -0.01646 262 GLY A N     
2088 C CA    . GLY A 264 ? 0.46576 0.26814 0.41411 0.02982  0.00804  -0.01580 262 GLY A CA    
2089 C C     . GLY A 264 ? 0.39850 0.23583 0.34312 0.05091  0.00555  -0.01369 262 GLY A C     
2090 O O     . GLY A 264 ? 0.48056 0.30990 0.42108 0.07340  -0.00077 -0.01873 262 GLY A O     
2091 N N     . PHE A 265 ? 0.38914 0.26436 0.33609 0.04434  0.01016  -0.00697 263 PHE A N     
2092 C CA    . PHE A 265 ? 0.38802 0.29765 0.33459 0.05817  0.00764  -0.00509 263 PHE A CA    
2093 C C     . PHE A 265 ? 0.42420 0.32534 0.35993 0.06850  0.00290  0.00918  263 PHE A C     
2094 O O     . PHE A 265 ? 0.40217 0.32714 0.34178 0.08629  -0.00292 0.00756  263 PHE A O     
2095 C CB    . PHE A 265 ? 0.37493 0.31771 0.32517 0.04581  0.01249  -0.00340 263 PHE A CB    
2096 C CG    . PHE A 265 ? 0.33844 0.29854 0.29585 0.04405  0.01388  -0.01579 263 PHE A CG    
2097 C CD1   . PHE A 265 ? 0.34222 0.32875 0.30156 0.05585  0.01299  -0.02338 263 PHE A CD1   
2098 C CD2   . PHE A 265 ? 0.34773 0.30199 0.30952 0.03211  0.01590  -0.01994 263 PHE A CD2   
2099 C CE1   . PHE A 265 ? 0.40683 0.40908 0.36549 0.05546  0.01409  -0.03324 263 PHE A CE1   
2100 C CE2   . PHE A 265 ? 0.32526 0.29679 0.29008 0.03327  0.01407  -0.03091 263 PHE A CE2   
2101 C CZ    . PHE A 265 ? 0.35640 0.34912 0.31614 0.04507  0.01307  -0.03678 263 PHE A CZ    
2102 N N     . PHE A 266 ? 0.43059 0.30353 0.35260 0.05833  0.00526  0.02343  264 PHE A N     
2103 C CA    . PHE A 266 ? 0.43770 0.29690 0.34230 0.07033  -0.00131 0.03901  264 PHE A CA    
2104 C C     . PHE A 266 ? 0.47985 0.29398 0.36595 0.05677  0.00458  0.05461  264 PHE A C     
2105 O O     . PHE A 266 ? 0.48615 0.29122 0.37911 0.03619  0.01450  0.05154  264 PHE A O     
2106 C CB    . PHE A 266 ? 0.44349 0.34384 0.34506 0.07009  -0.00467 0.04326  264 PHE A CB    
2107 C CG    . PHE A 266 ? 0.44139 0.35700 0.34215 0.04854  0.00428  0.04158  264 PHE A CG    
2108 C CD1   . PHE A 266 ? 0.51272 0.41071 0.39464 0.03644  0.01113  0.05212  264 PHE A CD1   
2109 C CD2   . PHE A 266 ? 0.43530 0.38252 0.35143 0.04243  0.00620  0.03021  264 PHE A CD2   
2110 C CE1   . PHE A 266 ? 0.52310 0.43601 0.40420 0.02215  0.01936  0.04744  264 PHE A CE1   
2111 C CE2   . PHE A 266 ? 0.43741 0.39104 0.35061 0.02731  0.01270  0.02821  264 PHE A CE2   
2112 C CZ    . PHE A 266 ? 0.44498 0.38226 0.34181 0.01903  0.01898  0.03496  264 PHE A CZ    
2113 N N     . ARG A 267 ? 0.54100 0.32926 0.40398 0.06879  -0.00179 0.07233  265 ARG A N     
2114 C CA    . ARG A 267 ? 0.58771 0.32925 0.42706 0.05540  0.00512  0.09240  265 ARG A CA    
2115 C C     . ARG A 267 ? 0.64025 0.39554 0.45165 0.05366  0.00603  0.11028  265 ARG A C     
2116 O O     . ARG A 267 ? 0.58736 0.37831 0.39567 0.06790  -0.00432 0.10781  265 ARG A O     
2117 C CB    . ARG A 267 ? 0.64014 0.32062 0.46563 0.07121  -0.00315 0.10221  265 ARG A CB    
2118 C CG    . ARG A 267 ? 0.72104 0.40794 0.53825 0.10708  -0.02029 0.10556  265 ARG A CG    
2119 C CD    . ARG A 267 ? 0.81664 0.43671 0.62089 0.12845  -0.02955 0.11203  265 ARG A CD    
2120 N NE    . ARG A 267 ? 0.93324 0.55473 0.72003 0.16380  -0.04628 0.12534  265 ARG A NE    
2121 C CZ    . ARG A 267 ? 0.90910 0.57276 0.71600 0.19562  -0.05877 0.10981  265 ARG A CZ    
2122 N NH1   . ARG A 267 ? 0.86453 0.56802 0.70452 0.19651  -0.05483 0.08222  265 ARG A NH1   
2123 N NH2   . ARG A 267 ? 0.94490 0.62752 0.74698 0.21973  -0.07308 0.11937  265 ARG A NH2   
2124 N N     . ARG A 268 ? 0.69489 0.42415 0.48559 0.03431  0.01886  0.12747  266 ARG A N     
2125 C CA    . ARG A 268 ? 0.75650 0.49164 0.51099 0.03240  0.02188  0.14640  266 ARG A CA    
2126 C C     . ARG A 268 ? 0.75233 0.43533 0.47017 0.04589  0.01409  0.17417  266 ARG A C     
2127 O O     . ARG A 268 ? 0.77683 0.41024 0.49353 0.03563  0.01978  0.18523  266 ARG A O     
2128 C CB    . ARG A 268 ? 0.77966 0.52484 0.53069 0.00412  0.04402  0.14965  266 ARG A CB    
2129 C CG    . ARG A 268 ? 0.88952 0.64967 0.60031 0.00317  0.04929  0.16388  266 ARG A CG    
2130 C CD    . ARG A 268 ? 0.97382 0.75022 0.68434 -0.02201 0.07413  0.16485  266 ARG A CD    
2131 N NE    . ARG A 268 ? 1.08871 0.90878 0.78770 -0.01924 0.07766  0.15168  266 ARG A NE    
2132 C CZ    . ARG A 268 ? 0.97195 0.81134 0.64812 -0.02812 0.09200  0.15777  266 ARG A CZ    
2133 N NH1   . ARG A 268 ? 1.06690 0.89605 0.73520 -0.04196 0.10278  0.17880  266 ARG A NH1   
2134 N NH2   . ARG A 268 ? 0.97114 0.84448 0.63670 -0.02288 0.09381  0.14007  266 ARG A NH2   
2135 N N     . GLU A 269 ? 0.82751 0.52531 0.51967 0.06766  -0.00101 0.18356  267 GLU A N     
2136 C CA    . GLU A 269 ? 0.91603 0.58838 0.58568 0.07780  -0.01081 0.20571  267 GLU A CA    
2137 C C     . GLU A 269 ? 0.95048 0.65648 0.58945 0.07114  -0.00922 0.21517  267 GLU A C     
2138 O O     . GLU A 269 ? 0.90002 0.64567 0.53219 0.08668  -0.02429 0.20692  267 GLU A O     
2139 C CB    . GLU A 269 ? 0.92202 0.59138 0.60050 0.11313  -0.03442 0.20245  267 GLU A CB    
2140 C CG    . GLU A 269 ? 1.04317 0.66487 0.74372 0.11987  -0.03492 0.19623  267 GLU A CG    
2141 C CD    . GLU A 269 ? 1.11671 0.74496 0.83218 0.15798  -0.05574 0.18709  267 GLU A CD    
2142 O OE1   . GLU A 269 ? 1.08140 0.72661 0.78327 0.17813  -0.07094 0.19819  267 GLU A OE1   
2143 O OE2   . GLU A 269 ? 1.05548 0.67751 0.79778 0.16817  -0.05664 0.16686  267 GLU A OE2   
2144 N N     A GLY A 270 ? 1.02150 0.71285 0.64341 0.04780  0.00796  0.23199  268 GLY A N     
2145 N N     B GLY A 270 ? 1.01615 0.71361 0.63955 0.04606  0.00958  0.22896  268 GLY A N     
2146 C CA    A GLY A 270 ? 0.96746 0.69035 0.55910 0.03806  0.01453  0.23905  268 GLY A CA    
2147 C CA    B GLY A 270 ? 0.96635 0.69615 0.55786 0.03966  0.01318  0.23586  268 GLY A CA    
2148 C C     A GLY A 270 ? 0.95765 0.72332 0.56013 0.02647  0.02680  0.21478  268 GLY A C     
2149 C C     B GLY A 270 ? 0.95231 0.73318 0.54161 0.04525  0.00724  0.21252  268 GLY A C     
2150 O O     A GLY A 270 ? 0.91337 0.68005 0.53631 0.00649  0.04710  0.20762  268 GLY A O     
2151 O O     B GLY A 270 ? 0.89837 0.70053 0.47265 0.06282  -0.01335 0.21042  268 GLY A O     
2152 N N     A ASP A 271 ? 0.93119 0.73329 0.52254 0.03911  0.01304  0.20048  269 ASP A N     
2153 N N     B ASP A 271 ? 0.94536 0.74667 0.55114 0.02972  0.02412  0.19391  269 ASP A N     
2154 C CA    A ASP A 271 ? 0.96928 0.80652 0.57099 0.03220  0.02013  0.17465  269 ASP A CA    
2155 C CA    B ASP A 271 ? 0.96159 0.80413 0.56678 0.03116  0.02134  0.16948  269 ASP A CA    
2156 C C     A ASP A 271 ? 0.90128 0.75412 0.52522 0.04728  0.00271  0.15605  269 ASP A C     
2157 C C     B ASP A 271 ? 0.90614 0.76473 0.52570 0.05019  -0.00189 0.15554  269 ASP A C     
2158 O O     A ASP A 271 ? 0.92280 0.80508 0.56212 0.04030  0.00471  0.13250  269 ASP A O     
2159 O O     B ASP A 271 ? 0.88306 0.77501 0.50030 0.05038  -0.00924 0.13604  269 ASP A O     
2160 C CB    . ASP A 271 ? 1.00728 0.87539 0.57583 0.02817  0.02098  0.16958  269 ASP A CB    
2161 C CG    A ASP A 271 ? 0.95286 0.82073 0.50653 0.00972  0.04545  0.18133  269 ASP A CG    
2162 O OD1   A ASP A 271 ? 0.96397 0.83415 0.54276 -0.00430 0.06631  0.17436  269 ASP A OD1   
2163 O OD2   A ASP A 271 ? 0.99371 0.86358 0.51178 0.00891  0.04376  0.19747  269 ASP A OD2   
2164 N N     . ALA A 272 ? 0.91364 0.75252 0.54990 0.06604  -0.01423 0.16324  270 ALA A N     
2165 C CA    . ALA A 272 ? 0.74734 0.61736 0.41925 0.07920  -0.03185 0.14439  270 ALA A CA    
2166 C C     . ALA A 272 ? 0.72845 0.58406 0.44363 0.07644  -0.02426 0.13512  270 ALA A C     
2167 O O     . ALA A 272 ? 0.74176 0.55435 0.45488 0.07133  -0.01301 0.14705  270 ALA A O     
2168 C CB    . ALA A 272 ? 0.77549 0.65378 0.43503 0.10722  -0.05738 0.15524  270 ALA A CB    
2169 N N     . PHE A 273 ? 0.64638 0.53865 0.39910 0.07769  -0.03047 0.11335  271 PHE A N     
2170 C CA    . PHE A 273 ? 0.57998 0.46720 0.37018 0.07588  -0.02395 0.10128  271 PHE A CA    
2171 C C     . PHE A 273 ? 0.58847 0.49421 0.40100 0.09993  -0.03949 0.09578  271 PHE A C     
2172 O O     . PHE A 273 ? 0.59717 0.54549 0.41521 0.10948  -0.05381 0.09117  271 PHE A O     
2173 C CB    . PHE A 273 ? 0.55870 0.47296 0.37219 0.05671  -0.01401 0.08169  271 PHE A CB    
2174 C CG    . PHE A 273 ? 0.56807 0.46795 0.36890 0.03762  0.00329  0.08291  271 PHE A CG    
2175 C CD1   . PHE A 273 ? 0.55943 0.42869 0.36307 0.02927  0.01652  0.09005  271 PHE A CD1   
2176 C CD2   . PHE A 273 ? 0.59087 0.51007 0.37856 0.02807  0.00616  0.07488  271 PHE A CD2   
2177 C CE1   . PHE A 273 ? 0.62647 0.49467 0.42448 0.01208  0.03374  0.09046  271 PHE A CE1   
2178 C CE2   . PHE A 273 ? 0.64298 0.55527 0.42102 0.01522  0.02337  0.07375  271 PHE A CE2   
2179 C CZ    . PHE A 273 ? 0.60545 0.49735 0.39088 0.00749  0.03780  0.08222  271 PHE A CZ    
2180 N N     . PHE A 274 ? 0.57898 0.45680 0.40649 0.10917  -0.03646 0.09350  272 PHE A N     
2181 C CA    . PHE A 274 ? 0.52894 0.42346 0.37830 0.13609  -0.04806 0.08514  272 PHE A CA    
2182 C C     . PHE A 274 ? 0.54914 0.44080 0.42534 0.13163  -0.03808 0.06720  272 PHE A C     
2183 O O     . PHE A 274 ? 0.52075 0.36688 0.39155 0.12081  -0.02876 0.06794  272 PHE A O     
2184 C CB    . PHE A 274 ? 0.60872 0.45877 0.43662 0.16473  -0.05983 0.10183  272 PHE A CB    
2185 C CG    . PHE A 274 ? 0.70233 0.55446 0.49745 0.17435  -0.07266 0.12217  272 PHE A CG    
2186 C CD1   . PHE A 274 ? 0.72604 0.54226 0.48322 0.15592  -0.06443 0.14141  272 PHE A CD1   
2187 C CD2   . PHE A 274 ? 0.65210 0.54816 0.45411 0.20252  -0.09303 0.12160  272 PHE A CD2   
2188 C CE1   . PHE A 274 ? 0.78165 0.60252 0.50427 0.16432  -0.07610 0.15924  272 PHE A CE1   
2189 C CE2   . PHE A 274 ? 0.69314 0.59686 0.46747 0.20810  -0.10619 0.13709  272 PHE A CE2   
2190 C CZ    . PHE A 274 ? 0.77909 0.64458 0.51340 0.18793  -0.09749 0.15501  272 PHE A CZ    
2191 N N     . ALA A 275 ? 0.53438 0.47785 0.43867 0.13808  -0.03997 0.05112  273 ALA A N     
2192 C CA    . ALA A 275 ? 0.54848 0.49318 0.47250 0.14055  -0.03246 0.03406  273 ALA A CA    
2193 C C     . ALA A 275 ? 0.62826 0.55201 0.55383 0.17471  -0.04091 0.02987  273 ALA A C     
2194 O O     . ALA A 275 ? 0.64449 0.56960 0.56327 0.19920  -0.05386 0.03963  273 ALA A O     
2195 C CB    . ALA A 275 ? 0.46748 0.47494 0.41602 0.13181  -0.02800 0.02128  273 ALA A CB    
2196 O OXT   . ALA A 275 ? 0.63660 0.53960 0.56816 0.18097  -0.03638 0.01547  273 ALA A OXT   
2197 O "O5'" . DA  B 1   ? 0.34635 0.67704 0.93869 -0.10125 0.10520  -0.24790 1   DA  B "O5'" 
2198 C "C5'" . DA  B 1   ? 0.35191 0.68174 0.84837 -0.10223 0.09677  -0.25813 1   DA  B "C5'" 
2199 C "C4'" . DA  B 1   ? 0.33092 0.70754 0.73627 -0.09390 0.07428  -0.23234 1   DA  B "C4'" 
2200 O "O4'" . DA  B 1   ? 0.30834 0.74960 0.76381 -0.08770 0.04314  -0.16914 1   DA  B "O4'" 
2201 C "C3'" . DA  B 1   ? 0.34667 0.72126 0.72064 -0.08818 0.07836  -0.24334 1   DA  B "C3'" 
2202 O "O3'" . DA  B 1   ? 0.33717 0.71789 0.58515 -0.07948 0.06768  -0.25134 1   DA  B "O3'" 
2203 C "C2'" . DA  B 1   ? 0.30694 0.73665 0.76775 -0.08063 0.04861  -0.19529 1   DA  B "C2'" 
2204 C "C1'" . DA  B 1   ? 0.29689 0.77364 0.75249 -0.07330 0.02484  -0.14718 1   DA  B "C1'" 
2205 N N9    . DA  B 1   ? 0.30630 0.82560 0.86928 -0.06486 0.00828  -0.09229 1   DA  B N9    
2206 C C8    . DA  B 1   ? 0.32248 0.90900 0.87860 -0.03868 -0.02284 -0.03636 1   DA  B C8    
2207 N N7    . DA  B 1   ? 0.28518 0.89669 0.94763 -0.03074 -0.02809 0.01091  1   DA  B N7    
2208 C C5    . DA  B 1   ? 0.28881 0.84279 1.03761 -0.05625 -0.00085 -0.01916 1   DA  B C5    
2209 C C6    . DA  B 1   ? 0.30093 0.83829 1.17244 -0.05994 0.00722  0.00370  1   DA  B C6    
2210 N N6    . DA  B 1   ? 0.31607 0.88983 1.23654 -0.03824 -0.00866 0.06769  1   DA  B N6    
2211 N N1    . DA  B 1   ? 0.32281 0.78545 1.22631 -0.07855 0.03214  -0.04276 1   DA  B N1    
2212 C C2    . DA  B 1   ? 0.31943 0.74545 1.16163 -0.09206 0.05153  -0.10597 1   DA  B C2    
2213 N N3    . DA  B 1   ? 0.30812 0.74467 1.03590 -0.09153 0.04984  -0.12921 1   DA  B N3    
2214 C C4    . DA  B 1   ? 0.33474 0.83340 1.02004 -0.07483 0.02145  -0.08388 1   DA  B C4    
2215 P P     . DA  B 2   ? 0.39074 0.75743 0.58666 -0.07510 0.06762  -0.27036 2   DA  B P     
2216 O OP1   . DA  B 2   ? 0.47269 0.82576 0.52839 -0.06536 0.06508  -0.28675 2   DA  B OP1   
2217 O OP2   . DA  B 2   ? 0.35755 0.68120 0.62258 -0.08639 0.10528  -0.29723 2   DA  B OP2   
2218 O "O5'" . DA  B 2   ? 0.32492 0.75552 0.55931 -0.06116 0.01980  -0.23059 2   DA  B "O5'" 
2219 C "C5'" . DA  B 2   ? 0.31935 0.80183 0.48786 -0.04019 -0.01464 -0.19642 2   DA  B "C5'" 
2220 C "C4'" . DA  B 2   ? 0.35123 0.89003 0.54544 -0.01546 -0.05969 -0.16566 2   DA  B "C4'" 
2221 O "O4'" . DA  B 2   ? 0.32990 0.89408 0.65152 -0.01688 -0.06148 -0.13525 2   DA  B "O4'" 
2222 C "C3'" . DA  B 2   ? 0.33666 0.85897 0.51650 -0.01155 -0.08041 -0.19884 2   DA  B "C3'" 
2223 O "O3'" . DA  B 2   ? 0.45504 1.03014 0.57647 0.02645  -0.13397 -0.17902 2   DA  B "O3'" 
2224 C "C2'" . DA  B 2   ? 0.32652 0.84333 0.64947 -0.02779 -0.07039 -0.20368 2   DA  B "C2'" 
2225 C "C1'" . DA  B 2   ? 0.30807 0.86421 0.70353 -0.02080 -0.06983 -0.15635 2   DA  B "C1'" 
2226 N N9    . DA  B 2   ? 0.29771 0.82221 0.80387 -0.04444 -0.03135 -0.16412 2   DA  B N9    
2227 C C8    . DA  B 2   ? 0.36174 0.82654 0.88466 -0.06819 0.01334  -0.20612 2   DA  B C8    
2228 N N7    . DA  B 2   ? 0.30105 0.75010 0.92374 -0.07743 0.04003  -0.20467 2   DA  B N7    
2229 C C5    . DA  B 2   ? 0.28969 0.78744 0.96936 -0.06293 0.01086  -0.15660 2   DA  B C5    
2230 C C6    . DA  B 2   ? 0.29057 0.79038 1.07623 -0.06157 0.01744  -0.12937 2   DA  B C6    
2231 N N6    . DA  B 2   ? 0.31409 0.75301 1.14480 -0.07180 0.05217  -0.15095 2   DA  B N6    
2232 N N1    . DA  B 2   ? 0.28578 0.83989 1.10540 -0.04153 -0.01311 -0.07385 2   DA  B N1    
2233 C C2    . DA  B 2   ? 0.28503 0.88917 1.02557 -0.01920 -0.04774 -0.04769 2   DA  B C2    
2234 N N3    . DA  B 2   ? 0.28790 0.89260 0.91719 -0.01545 -0.06097 -0.07329 2   DA  B N3    
2235 C C4    . DA  B 2   ? 0.28857 0.83564 0.89605 -0.04100 -0.03047 -0.12818 2   DA  B C4    
2236 P P     . DG  B 3   ? 0.32694 0.80007 0.85374 0.17223  -0.08408 -0.06784 3   DG  B P     
2237 O OP1   . DG  B 3   ? 0.32612 0.85845 0.89709 0.19539  -0.05902 -0.08810 3   DG  B OP1   
2238 O OP2   . DG  B 3   ? 0.48812 0.86274 0.97640 0.18143  -0.11524 -0.06461 3   DG  B OP2   
2239 O "O5'" . DG  B 3   ? 0.35926 0.82359 0.83493 0.15478  -0.05910 -0.07464 3   DG  B "O5'" 
2240 C "C5'" . DG  B 3   ? 0.27405 0.81262 0.75631 0.13006  -0.03168 -0.07207 3   DG  B "C5'" 
2241 C "C4'" . DG  B 3   ? 0.29794 0.80229 0.71568 0.10818  -0.02004 -0.06867 3   DG  B "C4'" 
2242 O "O4'" . DG  B 3   ? 0.32456 0.76642 0.69835 0.07810  -0.04479 -0.03644 3   DG  B "O4'" 
2243 C "C3'" . DG  B 3   ? 0.38188 0.81214 0.75560 0.13001  -0.01521 -0.08720 3   DG  B "C3'" 
2244 O "O3'" . DG  B 3   ? 0.49836 0.93130 0.82829 0.11101  0.01018  -0.08953 3   DG  B "O3'" 
2245 C "C2'" . DG  B 3   ? 0.40016 0.73820 0.73031 0.11964  -0.04417 -0.06471 3   DG  B "C2'" 
2246 C "C1'" . DG  B 3   ? 0.32136 0.67488 0.63313 0.08056  -0.04613 -0.03722 3   DG  B "C1'" 
2247 N N9    . DG  B 3   ? 0.34830 0.63020 0.62188 0.06425  -0.07286 -0.01339 3   DG  B N9    
2248 C C8    . DG  B 3   ? 0.37941 0.60567 0.64942 0.07645  -0.09921 -0.00961 3   DG  B C8    
2249 N N7    . DG  B 3   ? 0.38372 0.54984 0.60590 0.05413  -0.11602 0.01157  3   DG  B N7    
2250 C C5    . DG  B 3   ? 0.37570 0.55580 0.57159 0.02904  -0.10209 0.02167  3   DG  B C5    
2251 C C6    . DG  B 3   ? 0.34854 0.47649 0.48904 0.00240  -0.11171 0.04129  3   DG  B C6    
2252 O O6    . DG  B 3   ? 0.47943 0.54103 0.58091 -0.00485 -0.13120 0.05241  3   DG  B O6    
2253 N N1    . DG  B 3   ? 0.32704 0.48326 0.45540 -0.01784 -0.09832 0.04707  3   DG  B N1    
2254 C C2    . DG  B 3   ? 0.39904 0.62768 0.55986 -0.01668 -0.07556 0.03601  3   DG  B C2    
2255 N N2    . DG  B 3   ? 0.36847 0.60986 0.50440 -0.04365 -0.06906 0.04670  3   DG  B N2    
2256 N N3    . DG  B 3   ? 0.34565 0.62616 0.55533 0.00867  -0.06162 0.01498  3   DG  B N3    
2257 C C4    . DG  B 3   ? 0.32464 0.57566 0.55120 0.03246  -0.07714 0.00854  3   DG  B C4    
2258 P P     . DA  B 4   ? 0.48111 0.88665 0.78257 0.13126  0.02845  -0.11676 4   DA  B P     
2259 O OP1   . DA  B 4   ? 0.34853 0.80655 0.67305 0.14118  0.05104  -0.13651 4   DA  B OP1   
2260 O OP2   . DA  B 4   ? 0.44002 0.75947 0.71805 0.15043  0.00687  -0.11861 4   DA  B OP2   
2261 O "O5'" . DA  B 4   ? 0.39323 0.77986 0.63589 0.09529  0.04101  -0.10086 4   DA  B "O5'" 
2262 C "C5'" . DA  B 4   ? 0.26023 0.70798 0.50325 0.06238  0.05453  -0.08832 4   DA  B "C5'" 
2263 C "C4'" . DA  B 4   ? 0.28009 0.67556 0.46637 0.02985  0.04621  -0.06281 4   DA  B "C4'" 
2264 O "O4'" . DA  B 4   ? 0.26906 0.61689 0.44938 0.02392  0.02001  -0.04000 4   DA  B "O4'" 
2265 C "C3'" . DA  B 4   ? 0.31323 0.64564 0.45613 0.03699  0.04826  -0.06934 4   DA  B "C3'" 
2266 O "O3'" . DA  B 4   ? 0.31567 0.64015 0.41812 0.00471  0.05105  -0.05366 4   DA  B "O3'" 
2267 C "C2'" . DA  B 4   ? 0.28439 0.54624 0.41853 0.04951  0.02576  -0.05836 4   DA  B "C2'" 
2268 C "C1'" . DA  B 4   ? 0.25938 0.52850 0.39899 0.02900  0.01121  -0.03522 4   DA  B "C1'" 
2269 N N9    . DA  B 4   ? 0.30458 0.52788 0.44799 0.04115  -0.00968 -0.02792 4   DA  B N9    
2270 C C8    . DA  B 4   ? 0.31646 0.53170 0.48717 0.06786  -0.01825 -0.04050 4   DA  B C8    
2271 N N7    . DA  B 4   ? 0.27715 0.44366 0.43610 0.06718  -0.03951 -0.02742 4   DA  B N7    
2272 C C5    . DA  B 4   ? 0.27147 0.41292 0.39361 0.04185  -0.04259 -0.00798 4   DA  B C5    
2273 C C6    . DA  B 4   ? 0.27491 0.35926 0.36240 0.03004  -0.05980 0.00901  4   DA  B C6    
2274 N N6    . DA  B 4   ? 0.29163 0.33606 0.37380 0.03786  -0.07684 0.01145  4   DA  B N6    
2275 N N1    . DA  B 4   ? 0.33442 0.39956 0.38807 0.00922  -0.06048 0.02252  4   DA  B N1    
2276 C C2    . DA  B 4   ? 0.36896 0.46843 0.42295 -0.00266 -0.04785 0.02262  4   DA  B C2    
2277 N N3    . DA  B 4   ? 0.29052 0.44565 0.37107 0.00192  -0.03032 0.00943  4   DA  B N3    
2278 C C4    . DA  B 4   ? 0.27747 0.45128 0.39150 0.02639  -0.02680 -0.00727 4   DA  B C4    
2279 P P     . DC  B 5   ? 0.32494 0.60736 0.38562 0.00212  0.05560  -0.05827 5   DC  B P     
2280 O OP1   . DC  B 5   ? 0.38998 0.70238 0.42415 -0.03489 0.06228  -0.04689 5   DC  B OP1   
2281 O OP2   . DC  B 5   ? 0.34021 0.61742 0.40764 0.03115  0.06568  -0.08588 5   DC  B OP2   
2282 O "O5'" . DC  B 5   ? 0.31272 0.52082 0.35546 0.00703  0.03499  -0.04106 5   DC  B "O5'" 
2283 C "C5'" . DC  B 5   ? 0.29813 0.48172 0.32055 -0.01478 0.02126  -0.01719 5   DC  B "C5'" 
2284 C "C4'" . DC  B 5   ? 0.26601 0.38911 0.28009 -0.00042 0.00841  -0.00961 5   DC  B "C4'" 
2285 O "O4'" . DC  B 5   ? 0.28013 0.39746 0.31322 0.01405  0.00216  -0.01150 5   DC  B "O4'" 
2286 C "C3'" . DC  B 5   ? 0.27462 0.36967 0.28346 0.01630  0.01221  -0.01923 5   DC  B "C3'" 
2287 O "O3'" . DC  B 5   ? 0.29065 0.34639 0.28258 0.01207  0.00355  -0.00509 5   DC  B "O3'" 
2288 C "C2'" . DC  B 5   ? 0.29924 0.38031 0.32577 0.03951  0.00949  -0.02879 5   DC  B "C2'" 
2289 C "C1'" . DC  B 5   ? 0.27906 0.35348 0.30689 0.03252  -0.00062 -0.01555 5   DC  B "C1'" 
2290 N N1    . DC  B 5   ? 0.27883 0.34448 0.32256 0.04671  -0.00874 -0.01955 5   DC  B N1    
2291 C C2    . DC  B 5   ? 0.29926 0.32873 0.32756 0.04232  -0.02089 -0.00680 5   DC  B C2    
2292 O O2    . DC  B 5   ? 0.29310 0.30146 0.29815 0.03020  -0.02339 0.00478  5   DC  B O2    
2293 N N3    . DC  B 5   ? 0.26913 0.28384 0.30532 0.05094  -0.03210 -0.00787 5   DC  B N3    
2294 C C4    . DC  B 5   ? 0.31287 0.34577 0.37637 0.06670  -0.03400 -0.02092 5   DC  B C4    
2295 N N4    . DC  B 5   ? 0.33175 0.34269 0.40092 0.07314  -0.05111 -0.01890 5   DC  B N4    
2296 C C5    . DC  B 5   ? 0.28302 0.35254 0.36553 0.07652  -0.02076 -0.03744 5   DC  B C5    
2297 C C6    . DC  B 5   ? 0.29548 0.37985 0.36385 0.06447  -0.00702 -0.03618 5   DC  B C6    
2298 P P     . 8OG B 6   ? 0.31605 0.35362 0.30078 0.01533  0.00426  -0.00592 6   8OG B P     
2299 O OP1   . 8OG B 6   ? 0.32232 0.32921 0.30252 0.01462  -0.00538 0.00958  6   8OG B OP1   
2300 O OP2   . 8OG B 6   ? 0.31438 0.37509 0.28693 0.00076  0.00929  -0.01139 6   8OG B OP2   
2301 O "O5'" . 8OG B 6   ? 0.29482 0.31909 0.29026 0.03642  0.00728  -0.01824 6   8OG B "O5'" 
2302 C "C5'" . 8OG B 6   ? 0.29066 0.30307 0.28070 0.03911  0.00702  -0.02257 6   8OG B "C5'" 
2303 C "C4'" . 8OG B 6   ? 0.30041 0.28927 0.29201 0.03951  0.00210  -0.00846 6   8OG B "C4'" 
2304 O "O4'" . 8OG B 6   ? 0.30410 0.27698 0.30000 0.04958  0.00267  -0.00644 6   8OG B "O4'" 
2305 C "C3'" . 8OG B 6   ? 0.30519 0.28301 0.29347 0.03854  -0.00159 -0.00904 6   8OG B "C3'" 
2306 O "O3'" . 8OG B 6   ? 0.30673 0.28223 0.30394 0.03302  -0.00519 0.00703  6   8OG B "O3'" 
2307 C "C2'" . 8OG B 6   ? 0.30996 0.27015 0.29950 0.04991  -0.00298 -0.01469 6   8OG B "C2'" 
2308 C "C1'" . 8OG B 6   ? 0.29906 0.25633 0.29405 0.05422  0.00094  -0.00795 6   8OG B "C1'" 
2309 N N9    . 8OG B 6   ? 0.30857 0.25326 0.30102 0.06236  -0.00187 -0.01440 6   8OG B N9    
2310 C C8    . 8OG B 6   ? 0.32744 0.27476 0.32392 0.07000  -0.00696 -0.02652 6   8OG B C8    
2311 N N7    . 8OG B 6   ? 0.30007 0.23037 0.29530 0.07506  -0.01425 -0.02632 6   8OG B N7    
2312 C C5    . 8OG B 6   ? 0.31228 0.22671 0.29502 0.06864  -0.01010 -0.01445 6   8OG B C5    
2313 C C6    . 8OG B 6   ? 0.32884 0.21699 0.29451 0.06596  -0.01235 -0.00806 6   8OG B C6    
2314 O O6    . 8OG B 6   ? 0.33893 0.21044 0.29979 0.06756  -0.02491 -0.00995 6   8OG B O6    
2315 N N1    . 8OG B 6   ? 0.31791 0.20020 0.27280 0.06205  -0.00105 -0.00086 6   8OG B N1    
2316 C C2    . 8OG B 6   ? 0.31480 0.21572 0.28175 0.06224  0.00852  0.00246  6   8OG B C2    
2317 N N2    . 8OG B 6   ? 0.31443 0.21363 0.27811 0.06364  0.02022  0.00708  6   8OG B N2    
2318 N N3    . 8OG B 6   ? 0.28181 0.20332 0.26411 0.06153  0.00622  0.00065  6   8OG B N3    
2319 C C4    . 8OG B 6   ? 0.31721 0.24452 0.30301 0.06340  -0.00108 -0.00821 6   8OG B C4    
2320 O O8    . 8OG B 6   ? 0.32215 0.28712 0.32318 0.07290  -0.00546 -0.03866 6   8OG B O8    
2321 P P     . DT  B 7   ? 0.33142 0.30298 0.33137 0.02444  -0.01310 0.01565  7   DT  B P     
2322 O OP1   . DT  B 7   ? 0.34309 0.32429 0.36224 0.02081  -0.01762 0.03167  7   DT  B OP1   
2323 O OP2   . DT  B 7   ? 0.37274 0.33750 0.35015 0.01641  -0.01820 0.00526  7   DT  B OP2   
2324 O "O5'" . DT  B 7   ? 0.33276 0.29338 0.33676 0.03028  -0.01133 0.01632  7   DT  B "O5'" 
2325 C "C5'" . DT  B 7   ? 0.33720 0.30501 0.35844 0.03526  -0.00375 0.02567  7   DT  B "C5'" 
2326 C "C4'" . DT  B 7   ? 0.33316 0.28833 0.34581 0.03379  -0.00271 0.02547  7   DT  B "C4'" 
2327 O "O4'" . DT  B 7   ? 0.35477 0.29175 0.35151 0.04235  -0.00165 0.01373  7   DT  B "O4'" 
2328 C "C3'" . DT  B 7   ? 0.35543 0.29570 0.35451 0.02152  -0.01708 0.02681  7   DT  B "C3'" 
2329 O "O3'" . DT  B 7   ? 0.38775 0.33230 0.39131 0.00968  -0.01780 0.04030  7   DT  B "O3'" 
2330 C "C2'" . DT  B 7   ? 0.35503 0.26787 0.33253 0.03000  -0.02320 0.01058  7   DT  B "C2'" 
2331 C "C1'" . DT  B 7   ? 0.36780 0.28231 0.34875 0.03768  -0.01266 0.01091  7   DT  B "C1'" 
2332 N N1    . DT  B 7   ? 0.36945 0.26443 0.33952 0.04786  -0.01832 -0.00147 7   DT  B N1    
2333 C C2    . DT  B 7   ? 0.36435 0.24671 0.32583 0.04774  -0.01602 0.00220  7   DT  B C2    
2334 O O2    . DT  B 7   ? 0.36114 0.24996 0.32119 0.04151  -0.00488 0.01175  7   DT  B O2    
2335 N N3    . DT  B 7   ? 0.33942 0.20366 0.29491 0.05568  -0.02667 -0.00651 7   DT  B N3    
2336 C C4    . DT  B 7   ? 0.36585 0.22963 0.32967 0.06753  -0.03672 -0.02064 7   DT  B C4    
2337 O O4    . DT  B 7   ? 0.38875 0.24133 0.35559 0.07640  -0.04763 -0.02723 7   DT  B O4    
2338 C C5    . DT  B 7   ? 0.37862 0.25746 0.34778 0.06888  -0.03368 -0.02775 7   DT  B C5    
2339 C C7    . DT  B 7   ? 0.37658 0.25961 0.35223 0.08369  -0.03875 -0.04784 7   DT  B C7    
2340 C C6    . DT  B 7   ? 0.39054 0.28028 0.35891 0.05689  -0.02651 -0.01668 7   DT  B C6    
2341 P P     . DG  B 8   ? 0.36650 0.34082 0.39591 -0.00472 -0.02083 0.05920  8   DG  B P     
2342 O OP1   . DG  B 8   ? 0.32448 0.32161 0.37905 0.00463  -0.01592 0.06072  8   DG  B OP1   
2343 O OP2   . DG  B 8   ? 0.46293 0.41592 0.47285 -0.02351 -0.04200 0.06509  8   DG  B OP2   
2344 O "O5'" . DG  B 8   ? 0.35465 0.35258 0.39820 -0.00991 -0.00640 0.06972  8   DG  B "O5'" 
2345 C "C5'" . DG  B 8   ? 0.34644 0.36113 0.40323 0.00660  0.01500  0.06403  8   DG  B "C5'" 
2346 C "C4'" . DG  B 8   ? 0.37331 0.37637 0.40592 0.00049  0.02478  0.06261  8   DG  B "C4'" 
2347 O "O4'" . DG  B 8   ? 0.35675 0.31466 0.35436 0.00478  0.01371  0.05049  8   DG  B "O4'" 
2348 C "C3'" . DG  B 8   ? 0.35169 0.36240 0.37697 -0.02651 0.01870  0.07832  8   DG  B "C3'" 
2349 O "O3'" . DG  B 8   ? 0.39176 0.41682 0.40890 -0.03191 0.03884  0.07996  8   DG  B "O3'" 
2350 C "C2'" . DG  B 8   ? 0.41241 0.36846 0.39718 -0.03482 -0.00666 0.07368  8   DG  B "C2'" 
2351 C "C1'" . DG  B 8   ? 0.36379 0.29599 0.33370 -0.01409 -0.00022 0.05652  8   DG  B "C1'" 
2352 N N9    . DG  B 8   ? 0.41551 0.30608 0.36433 -0.00694 -0.02077 0.04462  8   DG  B N9    
2353 C C8    . DG  B 8   ? 0.42479 0.30282 0.37351 -0.00325 -0.03637 0.03811  8   DG  B C8    
2354 N N7    . DG  B 8   ? 0.43739 0.28314 0.37039 0.00860  -0.04934 0.02334  8   DG  B N7    
2355 C C5    . DG  B 8   ? 0.40732 0.24169 0.33050 0.01042  -0.04597 0.02344  8   DG  B C5    
2356 C C6    . DG  B 8   ? 0.42364 0.22786 0.33504 0.02133  -0.05899 0.01297  8   DG  B C6    
2357 O O6    . DG  B 8   ? 0.46170 0.24802 0.37475 0.03587  -0.07408 -0.00128 8   DG  B O6    
2358 N N1    . DG  B 8   ? 0.40802 0.20433 0.30535 0.01446  -0.05364 0.01972  8   DG  B N1    
2359 C C2    . DG  B 8   ? 0.43523 0.25217 0.32838 0.00173  -0.03321 0.03082  8   DG  B C2    
2360 N N2    . DG  B 8   ? 0.42871 0.22841 0.29748 -0.00496 -0.02974 0.03359  8   DG  B N2    
2361 N N3    . DG  B 8   ? 0.40604 0.25827 0.31756 -0.00406 -0.01803 0.03820  8   DG  B N3    
2362 C C4    . DG  B 8   ? 0.39409 0.25252 0.32123 -0.00030 -0.02763 0.03577  8   DG  B C4    
2363 P P     . DG  B 9   ? 0.39178 0.47249 0.43258 -0.05247 0.05511  0.09694  9   DG  B P     
2364 O OP1   . DG  B 9   ? 0.44512 0.57387 0.53307 -0.02732 0.07952  0.09051  9   DG  B OP1   
2365 O OP2   . DG  B 9   ? 0.43927 0.52558 0.48307 -0.08160 0.03243  0.11692  9   DG  B OP2   
2366 O "O5'" . DG  B 9   ? 0.46062 0.52137 0.45486 -0.06868 0.06595  0.09584  9   DG  B "O5'" 
2367 C "C5'" . DG  B 9   ? 0.45763 0.50538 0.43423 -0.04940 0.08635  0.07904  9   DG  B "C5'" 
2368 C "C4'" . DG  B 9   ? 0.49085 0.48766 0.40648 -0.06863 0.07733  0.07904  9   DG  B "C4'" 
2369 O "O4'" . DG  B 9   ? 0.52283 0.46220 0.41822 -0.06315 0.04473  0.07454  9   DG  B "O4'" 
2370 C "C3'" . DG  B 9   ? 0.56523 0.56859 0.45349 -0.10986 0.07347  0.09823  9   DG  B "C3'" 
2371 O "O3'" . DG  B 9   ? 0.61187 0.60379 0.45650 -0.12149 0.09175  0.09432  9   DG  B "O3'" 
2372 C "C2'" . DG  B 9   ? 0.58891 0.53141 0.44836 -0.12415 0.02981  0.10574  9   DG  B "C2'" 
2373 C "C1'" . DG  B 9   ? 0.53386 0.43398 0.38864 -0.09205 0.02002  0.08621  9   DG  B "C1'" 
2374 N N9    . DG  B 9   ? 0.57890 0.44213 0.43625 -0.08375 -0.01272 0.08295  9   DG  B N9    
2375 C C8    . DG  B 9   ? 0.54934 0.42836 0.43549 -0.07933 -0.02180 0.08506  9   DG  B C8    
2376 N N7    . DG  B 9   ? 0.49531 0.33191 0.37137 -0.06963 -0.04867 0.07646  9   DG  B N7    
2377 C C5    . DG  B 9   ? 0.52306 0.31779 0.37071 -0.06502 -0.05952 0.06914  9   DG  B C5    
2378 C C6    . DG  B 9   ? 0.54529 0.29119 0.38037 -0.05061 -0.08736 0.05698  9   DG  B C6    
2379 O O6    . DG  B 9   ? 0.55949 0.28941 0.40265 -0.03705 -0.10406 0.04669  9   DG  B O6    
2380 N N1    . DG  B 9   ? 0.56219 0.27799 0.37375 -0.05169 -0.09489 0.05591  9   DG  B N1    
2381 C C2    . DG  B 9   ? 0.59424 0.31968 0.38585 -0.06757 -0.07635 0.06449  9   DG  B C2    
2382 N N2    . DG  B 9   ? 0.58909 0.27508 0.35232 -0.07020 -0.09083 0.06375  9   DG  B N2    
2383 N N3    . DG  B 9   ? 0.57924 0.35076 0.37861 -0.07932 -0.04574 0.07225  9   DG  B N3    
2384 C C4    . DG  B 9   ? 0.56527 0.37218 0.39773 -0.07592 -0.03956 0.07451  9   DG  B C4    
2425 O "O5'" . DT  C 1   ? 1.88989 0.66633 1.95502 -0.26181 0.48899  -0.06025 1   DT  C "O5'" 
2426 C "C5'" . DT  C 1   ? 1.72912 0.65042 1.81474 -0.24483 0.48271  0.00566  1   DT  C "C5'" 
2427 C "C4'" . DT  C 1   ? 1.46353 0.67815 1.64188 -0.28074 0.36654  -0.09717 1   DT  C "C4'" 
2428 O "O4'" . DT  C 1   ? 1.28039 0.70425 1.46254 -0.24540 0.33829  -0.02009 1   DT  C "O4'" 
2429 C "C3'" . DT  C 1   ? 1.50577 0.81318 1.87104 -0.43796 0.36562  -0.23901 1   DT  C "C3'" 
2430 O "O3'" . DT  C 1   ? 1.59649 0.82714 1.96288 -0.45436 0.32420  -0.35545 1   DT  C "O3'" 
2431 C "C2'" . DT  C 1   ? 1.23727 0.88548 1.67064 -0.44393 0.26913  -0.27684 1   DT  C "C2'" 
2432 C "C1'" . DT  C 1   ? 1.15546 0.85178 1.46410 -0.32225 0.26349  -0.12354 1   DT  C "C1'" 
2433 N N1    . DT  C 1   ? 1.03128 0.86373 1.41386 -0.36799 0.30084  -0.05743 1   DT  C N1    
2434 C C2    . DT  C 1   ? 0.90230 0.98981 1.41967 -0.45647 0.25126  -0.14847 1   DT  C C2    
2435 O O2    . DT  C 1   ? 0.87498 1.08363 1.45183 -0.49416 0.17691  -0.28354 1   DT  C O2    
2436 N N3    . DT  C 1   ? 0.85060 1.04422 1.41568 -0.48367 0.28766  -0.07242 1   DT  C N3    
2437 C C4    . DT  C 1   ? 0.91468 0.98580 1.40645 -0.42942 0.36485  0.08108  1   DT  C C4    
2438 O O4    . DT  C 1   ? 0.87795 1.05752 1.37562 -0.42715 0.35336  0.14017  1   DT  C O4    
2439 C C5    . DT  C 1   ? 1.04951 0.85306 1.40593 -0.33752 0.42058  0.16616  1   DT  C C5    
2440 C C7    . DT  C 1   ? 1.13538 0.82305 1.36467 -0.23474 0.45181  0.29622  1   DT  C C7    
2441 C C6    . DT  C 1   ? 1.09992 0.80232 1.40539 -0.31012 0.38218  0.09325  1   DT  C C6    
2442 P P     . DG  C 2   ? 1.47833 0.83642 1.77626 -0.36837 0.19420  -0.43279 2   DG  C P     
2443 O OP1   . DG  C 2   ? 1.57874 0.83400 1.85419 -0.37015 0.17039  -0.49485 2   DG  C OP1   
2444 O OP2   . DG  C 2   ? 1.22614 0.90903 1.59906 -0.38016 0.10399  -0.48724 2   DG  C OP2   
2445 O "O5'" . DG  C 2   ? 1.38734 0.65512 1.49337 -0.20639 0.18808  -0.29429 2   DG  C "O5'" 
2446 C "C5'" . DG  C 2   ? 1.25194 0.56227 1.25639 -0.09855 0.09744  -0.32032 2   DG  C "C5'" 
2447 C "C4'" . DG  C 2   ? 1.20083 0.44423 1.05038 0.04273  0.10350  -0.18427 2   DG  C "C4'" 
2448 O "O4'" . DG  C 2   ? 1.12299 0.45411 0.98568 0.04690  0.13863  -0.08172 2   DG  C "O4'" 
2449 C "C3'" . DG  C 2   ? 1.03114 0.42802 0.80378 0.15615  -0.00058 -0.19477 2   DG  C "C3'" 
2450 O "O3'" . DG  C 2   ? 0.94439 0.34948 0.64939 0.22859  0.01158  -0.07715 2   DG  C "O3'" 
2451 C "C2'" . DG  C 2   ? 0.87220 0.53889 0.70157 0.14725  -0.04378 -0.17569 2   DG  C "C2'" 
2452 C "C1'" . DG  C 2   ? 0.91527 0.50132 0.76412 0.10965  0.04873  -0.07177 2   DG  C "C1'" 
2453 N N9    . DG  C 2   ? 0.83841 0.62512 0.80602 0.02047  0.04410  -0.09254 2   DG  C N9    
2454 C C8    . DG  C 2   ? 0.79239 0.76156 0.87740 -0.06825 -0.00751 -0.21798 2   DG  C C8    
2455 N N7    . DG  C 2   ? 0.70919 0.84489 0.87950 -0.13014 0.00020  -0.20564 2   DG  C N7    
2456 C C5    . DG  C 2   ? 0.69490 0.74822 0.79811 -0.07732 0.06026  -0.05892 2   DG  C C5    
2457 C C6    . DG  C 2   ? 0.62732 0.78003 0.76769 -0.10105 0.09490  0.02282  2   DG  C C6    
2458 O O6    . DG  C 2   ? 0.50527 0.85076 0.75010 -0.17961 0.07916  -0.01874 2   DG  C O6    
2459 N N1    . DG  C 2   ? 0.63832 0.64449 0.67470 -0.01462 0.15254  0.16599  2   DG  C N1    
2460 C C2    . DG  C 2   ? 0.72889 0.52744 0.64169 0.08293  0.17298  0.21836  2   DG  C C2    
2461 N N2    . DG  C 2   ? 0.73861 0.49190 0.59964 0.14267  0.19129  0.28198  2   DG  C N2    
2462 N N3    . DG  C 2   ? 0.78068 0.48775 0.65917 0.10175  0.14242  0.14366  2   DG  C N3    
2463 C C4    . DG  C 2   ? 0.77798 0.61766 0.75617 0.01778  0.08710  0.00864  2   DG  C C4    
2464 P P     . DT  C 3   ? 0.66394 0.34568 0.58502 -0.02205 0.14351  -0.14566 3   DT  C P     
2465 O OP1   . DT  C 3   ? 0.65225 0.32968 0.62164 -0.01054 0.17522  -0.15545 3   DT  C OP1   
2466 O OP2   . DT  C 3   ? 0.72175 0.41941 0.57677 -0.04485 0.13251  -0.14782 3   DT  C OP2   
2467 O "O5'" . DT  C 3   ? 0.58460 0.30981 0.55643 0.00467  0.11114  -0.11015 3   DT  C "O5'" 
2468 C "C5'" . DT  C 3   ? 0.52202 0.23848 0.54794 0.02198  0.10332  -0.09416 3   DT  C "C5'" 
2469 C "C4'" . DT  C 3   ? 0.49848 0.25269 0.54667 0.03710  0.07146  -0.06194 3   DT  C "C4'" 
2470 O "O4'" . DT  C 3   ? 0.54849 0.32065 0.55033 0.02339  0.04875  -0.05145 3   DT  C "O4'" 
2471 C "C3'" . DT  C 3   ? 0.48892 0.27394 0.55448 0.04842  0.07151  -0.05765 3   DT  C "C3'" 
2472 O "O3'" . DT  C 3   ? 0.47732 0.27626 0.59315 0.06562  0.05093  -0.03106 3   DT  C "O3'" 
2473 C "C2'" . DT  C 3   ? 0.43840 0.25015 0.44879 0.03524  0.05604  -0.05476 3   DT  C "C2'" 
2474 C "C1'" . DT  C 3   ? 0.50070 0.30844 0.49055 0.02615  0.03728  -0.04287 3   DT  C "C1'" 
2475 N N1    . DT  C 3   ? 0.50110 0.32088 0.44591 0.00702  0.02924  -0.04646 3   DT  C N1    
2476 C C2    . DT  C 3   ? 0.52269 0.36518 0.46304 0.00525  0.01133  -0.02932 3   DT  C C2    
2477 O O2    . DT  C 3   ? 0.45628 0.30488 0.41144 0.01473  0.00340  -0.01407 3   DT  C O2    
2478 N N3    . DT  C 3   ? 0.49146 0.34660 0.41010 -0.01104 0.00358  -0.03011 3   DT  C N3    
2479 C C4    . DT  C 3   ? 0.59007 0.43583 0.48006 -0.02956 0.00493  -0.04309 3   DT  C C4    
2480 O O4    . DT  C 3   ? 0.57955 0.43953 0.45812 -0.04563 -0.01027 -0.03661 3   DT  C O4    
2481 C C5    . DT  C 3   ? 0.58605 0.40150 0.46255 -0.03155 0.02597  -0.06395 3   DT  C C5    
2482 C C7    . DT  C 3   ? 0.67104 0.46449 0.49748 -0.05912 0.03176  -0.08184 3   DT  C C7    
2483 C C6    . DT  C 3   ? 0.55818 0.36318 0.46873 -0.01129 0.04032  -0.06592 3   DT  C C6    
2484 P P     . DC  C 4   ? 0.39918 0.22870 0.55084 0.07841  0.04535  -0.02097 4   DC  C P     
2485 O OP1   . DC  C 4   ? 0.38724 0.21225 0.61187 0.09355  0.03142  0.00170  4   DC  C OP1   
2486 O OP2   . DC  C 4   ? 0.44733 0.28008 0.59230 0.07555  0.07626  -0.04614 4   DC  C OP2   
2487 O "O5'" . DC  C 4   ? 0.39672 0.25283 0.50082 0.07080  0.01786  -0.00553 4   DC  C "O5'" 
2488 C "C5'" . DC  C 4   ? 0.44470 0.29638 0.53362 0.06630  -0.00713 0.01573  4   DC  C "C5'" 
2489 C "C4'" . DC  C 4   ? 0.37628 0.24824 0.41776 0.05661  -0.01835 0.02003  4   DC  C "C4'" 
2490 O "O4'" . DC  C 4   ? 0.40149 0.27578 0.40839 0.04651  -0.00568 0.00366  4   DC  C "O4'" 
2491 C "C3'" . DC  C 4   ? 0.37780 0.27476 0.42601 0.06118  -0.02250 0.02183  4   DC  C "C3'" 
2492 O "O3'" . DC  C 4   ? 0.39371 0.29383 0.42356 0.05488  -0.04458 0.04039  4   DC  C "O3'" 
2493 C "C2'" . DC  C 4   ? 0.33943 0.24997 0.35590 0.05472  -0.00876 0.00520  4   DC  C "C2'" 
2494 C "C1'" . DC  C 4   ? 0.34869 0.24685 0.33752 0.04391  -0.00765 0.00251  4   DC  C "C1'" 
2495 N N1    . DC  C 4   ? 0.39853 0.29977 0.36633 0.03415  0.00220  -0.01173 4   DC  C N1    
2496 C C2    . DC  C 4   ? 0.42325 0.33470 0.37326 0.02371  -0.00395 -0.00787 4   DC  C C2    
2497 O O2    . DC  C 4   ? 0.41449 0.33031 0.36417 0.02357  -0.00929 0.00256  4   DC  C O2    
2498 N N3    . DC  C 4   ? 0.44043 0.35489 0.37542 0.01127  -0.00362 -0.01476 4   DC  C N3    
2499 C C4    . DC  C 4   ? 0.46569 0.36736 0.38625 0.00540  0.00558  -0.02832 4   DC  C C4    
2500 N N4    . DC  C 4   ? 0.45772 0.35826 0.35147 -0.01372 0.00009  -0.03185 4   DC  C N4    
2501 C C5    . DC  C 4   ? 0.44200 0.32965 0.37731 0.01619  0.02146  -0.03796 4   DC  C C5    
2502 C C6    . DC  C 4   ? 0.41237 0.30321 0.37962 0.03223  0.01761  -0.02756 4   DC  C C6    
2503 P P     . DC  C 5   ? 0.37646 0.29580 0.41317 0.05581  -0.05627 0.04713  5   DC  C P     
2504 O OP1   . DC  C 5   ? 0.41410 0.32072 0.42886 0.04358  -0.08268 0.06886  5   DC  C OP1   
2505 O OP2   . DC  C 5   ? 0.37801 0.30964 0.46929 0.06912  -0.04777 0.04230  5   DC  C OP2   
2506 O "O5'" . DC  C 5   ? 0.36443 0.29780 0.36570 0.05036  -0.04310 0.03292  5   DC  C "O5'" 
2507 C "C5'" . DC  C 5   ? 0.37182 0.29784 0.33335 0.03887  -0.04003 0.03202  5   DC  C "C5'" 
2508 C "C4'" . DC  C 5   ? 0.36398 0.30654 0.31769 0.03795  -0.02709 0.02068  5   DC  C "C4'" 
2509 O "O4'" . DC  C 5   ? 0.35359 0.30068 0.31523 0.03992  -0.01738 0.01137  5   DC  C "O4'" 
2510 C "C3'" . DC  C 5   ? 0.37603 0.33467 0.34159 0.04256  -0.02842 0.01878  5   DC  C "C3'" 
2511 O "O3'" . DC  C 5   ? 0.37559 0.33947 0.32716 0.03708  -0.02185 0.01533  5   DC  C "O3'" 
2512 C "C2'" . DC  C 5   ? 0.32789 0.29599 0.31088 0.04887  -0.01824 0.00972  5   DC  C "C2'" 
2513 C "C1'" . DC  C 5   ? 0.35169 0.31486 0.31944 0.04230  -0.01306 0.00596  5   DC  C "C1'" 
2514 N N1    . DC  C 5   ? 0.34590 0.30649 0.31125 0.03927  -0.00574 -0.00302 5   DC  C N1    
2515 C C2    . DC  C 5   ? 0.36337 0.32714 0.31665 0.02890  -0.00757 -0.00327 5   DC  C C2    
2516 O O2    . DC  C 5   ? 0.37407 0.34576 0.33285 0.02676  -0.01119 0.00363  5   DC  C O2    
2517 N N3    . DC  C 5   ? 0.36592 0.32162 0.30315 0.01880  -0.00470 -0.01083 5   DC  C N3    
2518 C C4    . DC  C 5   ? 0.41328 0.35557 0.34594 0.01999  0.00837  -0.02249 5   DC  C C4    
2519 N N4    . DC  C 5   ? 0.43069 0.35713 0.33389 0.00395  0.01532  -0.03342 5   DC  C N4    
2520 C C5    . DC  C 5   ? 0.38115 0.32356 0.34178 0.03502  0.01541  -0.02305 5   DC  C C5    
2521 C C6    . DC  C 5   ? 0.38411 0.33741 0.36050 0.04366  0.00351  -0.01076 5   DC  C C6    
2522 P P     . DA  C 6   ? 0.37390 0.32694 0.30161 0.02688  -0.02553 0.01779  6   DA  C P     
2523 O OP1   . DA  C 6   ? 0.37809 0.30813 0.27683 0.01551  -0.03382 0.02575  6   DA  C OP1   
2524 O OP2   . DA  C 6   ? 0.37739 0.34008 0.31860 0.02968  -0.03573 0.02019  6   DA  C OP2   
2525 O "O5'" . DA  C 6   ? 0.36383 0.32022 0.29180 0.02408  -0.00620 0.00909  6   DA  C "O5'" 
2526 C "C5'" . DA  C 6   ? 0.37560 0.32475 0.30017 0.01890  0.00726  0.00698  6   DA  C "C5'" 
2527 C "C4'" . DA  C 6   ? 0.31752 0.28297 0.27691 0.02332  0.01981  0.00418  6   DA  C "C4'" 
2528 O "O4'" . DA  C 6   ? 0.31533 0.29831 0.29456 0.03014  0.00781  0.00899  6   DA  C "O4'" 
2529 C "C3'" . DA  C 6   ? 0.33424 0.30309 0.30639 0.02493  0.02724  0.00028  6   DA  C "C3'" 
2530 O "O3'" . DA  C 6   ? 0.30645 0.27981 0.31485 0.02512  0.04552  -0.00130 6   DA  C "O3'" 
2531 C "C2'" . DA  C 6   ? 0.34238 0.32984 0.32933 0.03358  0.01129  0.00599  6   DA  C "C2'" 
2532 C "C1'" . DA  C 6   ? 0.30621 0.30269 0.30184 0.03468  0.00408  0.01090  6   DA  C "C1'" 
2533 N N9    . DA  C 6   ? 0.31861 0.31927 0.30507 0.03729  -0.00635 0.01139  6   DA  C N9    
2534 C C8    . DA  C 6   ? 0.34529 0.34244 0.32319 0.04108  -0.00964 0.00899  6   DA  C C8    
2535 N N7    . DA  C 6   ? 0.33135 0.33047 0.30946 0.04243  -0.01004 0.00663  6   DA  C N7    
2536 C C5    . DA  C 6   ? 0.31813 0.31893 0.29158 0.03562  -0.01094 0.00772  6   DA  C C5    
2537 C C6    . DA  C 6   ? 0.34482 0.34087 0.30305 0.02741  -0.01068 0.00418  6   DA  C C6    
2538 N N6    . DA  C 6   ? 0.34016 0.32782 0.29002 0.02770  -0.00068 -0.00509 6   DA  C N6    
2539 N N1    . DA  C 6   ? 0.34337 0.34119 0.29666 0.01602  -0.01974 0.01022  6   DA  C N1    
2540 C C2    . DA  C 6   ? 0.31563 0.32366 0.29386 0.01730  -0.02506 0.01951  6   DA  C C2    
2541 N N3    . DA  C 6   ? 0.29706 0.30821 0.29413 0.02641  -0.01737 0.01972  6   DA  C N3    
2542 C C4    . DA  C 6   ? 0.29308 0.29807 0.27847 0.03349  -0.01186 0.01316  6   DA  C C4    
2543 O "O5'" . 3DR C 7   ? 0.37892 0.33122 0.41534 0.02033  0.08745  -0.01780 7   3DR C "O5'" 
2544 P P     . 3DR C 7   ? 0.32536 0.27546 0.32833 0.01521  0.07736  -0.01416 7   3DR C P     
2545 O OP1   . 3DR C 7   ? 0.35815 0.31327 0.39936 0.01401  0.09615  -0.01338 7   3DR C OP1   
2546 O OP2   . 3DR C 7   ? 0.45484 0.37491 0.38988 -0.00005 0.07799  -0.02157 7   3DR C OP2   
2547 C "C2'" . 3DR C 7   ? 0.32385 0.25902 0.34612 0.01893  0.07501  -0.02744 7   3DR C "C2'" 
2548 C "C5'" . 3DR C 7   ? 0.32934 0.29309 0.36355 0.02667  0.06550  -0.01145 7   3DR C "C5'" 
2549 C "C4'" . 3DR C 7   ? 0.33594 0.27629 0.33214 0.01701  0.07139  -0.02317 7   3DR C "C4'" 
2550 O "O4'" . 3DR C 7   ? 0.44057 0.35875 0.44981 0.01049  0.10482  -0.03747 7   3DR C "O4'" 
2551 C "C1'" . 3DR C 7   ? 0.38310 0.29166 0.39757 0.00916  0.10842  -0.04327 7   3DR C "C1'" 
2552 C "C3'" . 3DR C 7   ? 0.30399 0.25721 0.31216 0.02317  0.05451  -0.01692 7   3DR C "C3'" 
2553 O "O3'" . 3DR C 7   ? 0.31824 0.26793 0.28599 0.01694  0.03509  -0.01610 7   3DR C "O3'" 
2554 P P     . DG  C 8   ? 0.30963 0.28488 0.28992 0.02666  0.01182  -0.00395 8   DG  C P     
2555 O OP1   . DG  C 8   ? 0.32823 0.29581 0.28108 0.01839  -0.00382 -0.00323 8   DG  C OP1   
2556 O OP2   . DG  C 8   ? 0.29523 0.28498 0.28898 0.03444  0.00844  0.00269  8   DG  C OP2   
2557 O "O5'" . DG  C 8   ? 0.31715 0.30272 0.32667 0.03110  0.01288  -0.00038 8   DG  C "O5'" 
2558 C "C5'" . DG  C 8   ? 0.32560 0.30474 0.32883 0.02479  0.00941  -0.00357 8   DG  C "C5'" 
2559 C "C4'" . DG  C 8   ? 0.31001 0.30120 0.34481 0.03008  0.00982  0.00411  8   DG  C "C4'" 
2560 O "O4'" . DG  C 8   ? 0.31779 0.32956 0.35995 0.03610  0.00062  0.01490  8   DG  C "O4'" 
2561 C "C3'" . DG  C 8   ? 0.28590 0.27433 0.32116 0.02355  0.00531  0.00287  8   DG  C "C3'" 
2562 O "O3'" . DG  C 8   ? 0.28998 0.27567 0.35394 0.02559  0.01331  0.00751  8   DG  C "O3'" 
2563 C "C2'" . DG  C 8   ? 0.28029 0.29076 0.31987 0.02681  -0.00716 0.01104  8   DG  C "C2'" 
2564 C "C1'" . DG  C 8   ? 0.30241 0.32383 0.34667 0.03422  -0.00504 0.01795  8   DG  C "C1'" 
2565 N N9    . DG  C 8   ? 0.30692 0.33860 0.34450 0.03698  -0.00862 0.01800  8   DG  C N9    
2566 C C8    . DG  C 8   ? 0.32289 0.35244 0.35409 0.03815  -0.01436 0.01420  8   DG  C C8    
2567 N N7    . DG  C 8   ? 0.32644 0.36415 0.36441 0.04235  -0.01244 0.01454  8   DG  C N7    
2568 C C5    . DG  C 8   ? 0.32424 0.36726 0.36097 0.04031  -0.00342 0.01651  8   DG  C C5    
2569 C C6    . DG  C 8   ? 0.29318 0.33829 0.32514 0.03827  0.00785  0.01369  8   DG  C C6    
2570 O O6    . DG  C 8   ? 0.30651 0.35064 0.34630 0.04192  0.01524  0.00726  8   DG  C O6    
2571 N N1    . DG  C 8   ? 0.28708 0.33080 0.30254 0.02853  0.01197  0.01929  8   DG  C N1    
2572 C C2    . DG  C 8   ? 0.28856 0.33209 0.30654 0.02543  0.00323  0.02974  8   DG  C C2    
2573 N N2    . DG  C 8   ? 0.29589 0.33608 0.29703 0.01335  0.00273  0.04003  8   DG  C N2    
2574 N N3    . DG  C 8   ? 0.27219 0.31431 0.30668 0.03120  -0.00323 0.03016  8   DG  C N3    
2575 C C4    . DG  C 8   ? 0.29282 0.33350 0.32971 0.03677  -0.00484 0.02174  8   DG  C C4    
2576 P P     . DT  C 9   ? 0.27879 0.25919 0.35127 0.01832  0.01178  0.00763  9   DT  C P     
2577 O OP1   . DT  C 9   ? 0.27720 0.23716 0.37398 0.01831  0.02757  0.00423  9   DT  C OP1   
2578 O OP2   . DT  C 9   ? 0.30161 0.27837 0.35034 0.00716  0.00165  0.00027  9   DT  C OP2   
2579 O "O5'" . DT  C 9   ? 0.26501 0.26884 0.35296 0.02242  0.00325  0.02471  9   DT  C "O5'" 
2580 C "C5'" . DT  C 9   ? 0.24952 0.25730 0.35577 0.02704  0.00269  0.03919  9   DT  C "C5'" 
2581 C "C4'" . DT  C 9   ? 0.26647 0.28711 0.36774 0.02184  -0.00413 0.05370  9   DT  C "C4'" 
2582 O "O4'" . DT  C 9   ? 0.26829 0.30114 0.34541 0.02170  -0.00455 0.04882  9   DT  C "O4'" 
2583 C "C3'" . DT  C 9   ? 0.29371 0.31309 0.40215 0.01454  -0.00175 0.05489  9   DT  C "C3'" 
2584 O "O3'" . DT  C 9   ? 0.32594 0.34259 0.44363 0.00846  -0.00575 0.07482  9   DT  C "O3'" 
2585 C "C2'" . DT  C 9   ? 0.30135 0.33644 0.39632 0.01198  0.00040  0.04822  9   DT  C "C2'" 
2586 C "C1'" . DT  C 9   ? 0.29402 0.33489 0.36873 0.01523  0.00030  0.04926  9   DT  C "C1'" 
2587 N N1    . DT  C 9   ? 0.28567 0.33612 0.35577 0.01920  0.00427  0.03800  9   DT  C N1    
2588 C C2    . DT  C 9   ? 0.29179 0.34707 0.34837 0.01538  0.01476  0.03713  9   DT  C C2    
2589 O O2    . DT  C 9   ? 0.32077 0.37120 0.35702 0.00461  0.01966  0.04512  9   DT  C O2    
2590 N N3    . DT  C 9   ? 0.29626 0.35777 0.36211 0.02178  0.01994  0.02703  9   DT  C N3    
2591 C C4    . DT  C 9   ? 0.29644 0.36091 0.38012 0.02966  0.00908  0.02281  9   DT  C C4    
2592 O O4    . DT  C 9   ? 0.29510 0.36443 0.39388 0.03513  0.01069  0.01856  9   DT  C O4    
2593 C C5    . DT  C 9   ? 0.29337 0.34991 0.37468 0.02826  -0.00362 0.02424  9   DT  C C5    
2594 C C7    . DT  C 9   ? 0.27203 0.32372 0.35412 0.02813  -0.01752 0.02084  9   DT  C C7    
2595 C C6    . DT  C 9   ? 0.28799 0.33729 0.36459 0.02419  -0.00214 0.02920  9   DT  C C6    
# 
