data_8UTD
# 
_entry.id   8UTD 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UTD         pdb_00008utd 10.2210/pdb8utd/pdb 
WWPDB D_1000278747 ?            ?                   
EMDB  EMD-42538    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
7 'Structure model' 1 1 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    7 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Data collection' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' em_admin    
2 7 'Structure model' em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 7 'Structure model' '_em_admin.last_update' 
2 7 'Structure model' '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UTD 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'CryoEM Structure of HCA2-Gi1 in complex with MK-1903' 
_pdbx_database_related.db_id          EMD-42538 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              bryan_roth@med.unc.edu 
_pdbx_contact_author.name_first         Bryan 
_pdbx_contact_author.name_last          Roth 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0561-6520 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Krumm, B.E.'   1  0000-0001-6039-4767 
'Kang, H.J.'    2  ?                   
'Diberto, J.F.' 3  ?                   
'Kapolka, N.J.' 4  ?                   
'Gumpper, R.H.' 5  ?                   
'Olsen, R.H.J.' 6  ?                   
'Huang, X.P.'   7  ?                   
'Zhang, S.'     8  ?                   
'Fay, J.F.'     9  ?                   
'Roth, B.L.'    10 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Cell 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1097-4172 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            187 
_citation.language                  ? 
_citation.page_first                7433 
_citation.page_last                 7449.e20 
_citation.title                     'Structure-guided design of a peripherally restricted chemogenetic system.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.cell.2024.11.001 
_citation.pdbx_database_id_PubMed   39631393 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kang, H.J.'       1  ? 
primary 'Krumm, B.E.'      2  ? 
primary 'Tassou, A.'       3  ? 
primary 'Geron, M.'        4  ? 
primary 'DiBerto, J.F.'    5  ? 
primary 'Kapolka, N.J.'    6  ? 
primary 'Gumpper, R.H.'    7  ? 
primary 'Sakamoto, K.'     8  ? 
primary 'Dewran Kocak, D.' 9  ? 
primary 'Olsen, R.H.J.'    10 ? 
primary 'Huang, X.P.'      11 ? 
primary 'Zhang, S.'        12 ? 
primary 'Huang, K.L.'      13 ? 
primary 'Zaidi, S.A.'      14 ? 
primary 'Nguyen, M.T.'     15 ? 
primary 'Jo, M.J.'         16 ? 
primary 'Katritch, V.'     17 ? 
primary 'Fay, J.F.'        18 ? 
primary 'Scherrer, G.'     19 ? 
primary 'Roth, B.L.'       20 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Hydroxycarboxylic acid receptor 2'                                                            42297.867 1 ? 
D124A ? ? 
2 polymer     man scFv16                                                                                         28668.922 1 ? ? ? 
? 
3 polymer     man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'                                      40445.059 1 ? ? ? 
? 
4 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'                             39418.086 1 ? ? ? 
? 
5 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'                            7861.143  1 ? ? ? 
? 
6 non-polymer syn '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 164.161   1 ? ? ? 
? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
3 'Adenylate cyclase-inhibiting G alpha protein' 
4 'Transducin beta chain 1'                      
5 'G gamma-I'                                    
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;QGGTTMNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFL
LIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVARYFRVVHPHHALNKISNRTAAIISCLLWGIT
IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMV
VAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR
KMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
;
;QGGTTMNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFL
LIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVARYFRVVHPHHALNKISNRTAAIISCLLWGIT
IGLTVHLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMV
VAIVFVICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQR
KMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
;
R ? 
2 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELKAAALEVLFQGPHHHHHHHH
;
D ? 
3 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
4 'polypeptide(L)' no no 
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
;
B ? 
5 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL C ? 
# 
_pdbx_entity_nonpoly.entity_id   6 
_pdbx_entity_nonpoly.name        '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 
_pdbx_entity_nonpoly.comp_id     XOT 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   GLY n 
1 3   GLY n 
1 4   THR n 
1 5   THR n 
1 6   MET n 
1 7   ASN n 
1 8   ARG n 
1 9   HIS n 
1 10  HIS n 
1 11  LEU n 
1 12  GLN n 
1 13  ASP n 
1 14  HIS n 
1 15  PHE n 
1 16  LEU n 
1 17  GLU n 
1 18  ILE n 
1 19  ASP n 
1 20  LYS n 
1 21  LYS n 
1 22  ASN n 
1 23  CYS n 
1 24  CYS n 
1 25  VAL n 
1 26  PHE n 
1 27  ARG n 
1 28  ASP n 
1 29  ASP n 
1 30  PHE n 
1 31  ILE n 
1 32  VAL n 
1 33  LYS n 
1 34  VAL n 
1 35  LEU n 
1 36  PRO n 
1 37  PRO n 
1 38  VAL n 
1 39  LEU n 
1 40  GLY n 
1 41  LEU n 
1 42  GLU n 
1 43  PHE n 
1 44  ILE n 
1 45  PHE n 
1 46  GLY n 
1 47  LEU n 
1 48  LEU n 
1 49  GLY n 
1 50  ASN n 
1 51  GLY n 
1 52  LEU n 
1 53  ALA n 
1 54  LEU n 
1 55  TRP n 
1 56  ILE n 
1 57  PHE n 
1 58  CYS n 
1 59  PHE n 
1 60  HIS n 
1 61  LEU n 
1 62  LYS n 
1 63  SER n 
1 64  TRP n 
1 65  LYS n 
1 66  SER n 
1 67  SER n 
1 68  ARG n 
1 69  ILE n 
1 70  PHE n 
1 71  LEU n 
1 72  PHE n 
1 73  ASN n 
1 74  LEU n 
1 75  ALA n 
1 76  VAL n 
1 77  ALA n 
1 78  ASP n 
1 79  PHE n 
1 80  LEU n 
1 81  LEU n 
1 82  ILE n 
1 83  ILE n 
1 84  CYS n 
1 85  LEU n 
1 86  PRO n 
1 87  PHE n 
1 88  LEU n 
1 89  MET n 
1 90  ASP n 
1 91  ASN n 
1 92  TYR n 
1 93  VAL n 
1 94  ARG n 
1 95  ARG n 
1 96  TRP n 
1 97  ASP n 
1 98  TRP n 
1 99  LYS n 
1 100 PHE n 
1 101 GLY n 
1 102 ASP n 
1 103 ILE n 
1 104 PRO n 
1 105 CYS n 
1 106 ARG n 
1 107 LEU n 
1 108 MET n 
1 109 LEU n 
1 110 PHE n 
1 111 MET n 
1 112 LEU n 
1 113 ALA n 
1 114 MET n 
1 115 ASN n 
1 116 ARG n 
1 117 GLN n 
1 118 GLY n 
1 119 SER n 
1 120 ILE n 
1 121 ILE n 
1 122 PHE n 
1 123 LEU n 
1 124 THR n 
1 125 VAL n 
1 126 VAL n 
1 127 ALA n 
1 128 VAL n 
1 129 ALA n 
1 130 ARG n 
1 131 TYR n 
1 132 PHE n 
1 133 ARG n 
1 134 VAL n 
1 135 VAL n 
1 136 HIS n 
1 137 PRO n 
1 138 HIS n 
1 139 HIS n 
1 140 ALA n 
1 141 LEU n 
1 142 ASN n 
1 143 LYS n 
1 144 ILE n 
1 145 SER n 
1 146 ASN n 
1 147 ARG n 
1 148 THR n 
1 149 ALA n 
1 150 ALA n 
1 151 ILE n 
1 152 ILE n 
1 153 SER n 
1 154 CYS n 
1 155 LEU n 
1 156 LEU n 
1 157 TRP n 
1 158 GLY n 
1 159 ILE n 
1 160 THR n 
1 161 ILE n 
1 162 GLY n 
1 163 LEU n 
1 164 THR n 
1 165 VAL n 
1 166 HIS n 
1 167 LEU n 
1 168 LEU n 
1 169 LYS n 
1 170 LYS n 
1 171 LYS n 
1 172 MET n 
1 173 PRO n 
1 174 ILE n 
1 175 GLN n 
1 176 ASN n 
1 177 GLY n 
1 178 GLY n 
1 179 ALA n 
1 180 ASN n 
1 181 LEU n 
1 182 CYS n 
1 183 SER n 
1 184 SER n 
1 185 PHE n 
1 186 SER n 
1 187 ILE n 
1 188 CYS n 
1 189 HIS n 
1 190 THR n 
1 191 PHE n 
1 192 GLN n 
1 193 TRP n 
1 194 HIS n 
1 195 GLU n 
1 196 ALA n 
1 197 MET n 
1 198 PHE n 
1 199 LEU n 
1 200 LEU n 
1 201 GLU n 
1 202 PHE n 
1 203 PHE n 
1 204 LEU n 
1 205 PRO n 
1 206 LEU n 
1 207 GLY n 
1 208 ILE n 
1 209 ILE n 
1 210 LEU n 
1 211 PHE n 
1 212 CYS n 
1 213 SER n 
1 214 ALA n 
1 215 ARG n 
1 216 ILE n 
1 217 ILE n 
1 218 TRP n 
1 219 SER n 
1 220 LEU n 
1 221 ARG n 
1 222 GLN n 
1 223 ARG n 
1 224 GLN n 
1 225 MET n 
1 226 ASP n 
1 227 ARG n 
1 228 HIS n 
1 229 ALA n 
1 230 LYS n 
1 231 ILE n 
1 232 LYS n 
1 233 ARG n 
1 234 ALA n 
1 235 ILE n 
1 236 THR n 
1 237 PHE n 
1 238 ILE n 
1 239 MET n 
1 240 VAL n 
1 241 VAL n 
1 242 ALA n 
1 243 ILE n 
1 244 VAL n 
1 245 PHE n 
1 246 VAL n 
1 247 ILE n 
1 248 CYS n 
1 249 PHE n 
1 250 LEU n 
1 251 PRO n 
1 252 SER n 
1 253 VAL n 
1 254 VAL n 
1 255 VAL n 
1 256 ARG n 
1 257 ILE n 
1 258 ARG n 
1 259 ILE n 
1 260 PHE n 
1 261 TRP n 
1 262 LEU n 
1 263 LEU n 
1 264 HIS n 
1 265 THR n 
1 266 SER n 
1 267 GLY n 
1 268 THR n 
1 269 GLN n 
1 270 ASN n 
1 271 CYS n 
1 272 GLU n 
1 273 VAL n 
1 274 TYR n 
1 275 ARG n 
1 276 SER n 
1 277 VAL n 
1 278 ASP n 
1 279 LEU n 
1 280 ALA n 
1 281 PHE n 
1 282 PHE n 
1 283 ILE n 
1 284 THR n 
1 285 LEU n 
1 286 SER n 
1 287 PHE n 
1 288 THR n 
1 289 TYR n 
1 290 MET n 
1 291 ASN n 
1 292 SER n 
1 293 MET n 
1 294 LEU n 
1 295 ASP n 
1 296 PRO n 
1 297 VAL n 
1 298 VAL n 
1 299 TYR n 
1 300 TYR n 
1 301 PHE n 
1 302 SER n 
1 303 SER n 
1 304 PRO n 
1 305 SER n 
1 306 PHE n 
1 307 PRO n 
1 308 ASN n 
1 309 PHE n 
1 310 PHE n 
1 311 SER n 
1 312 THR n 
1 313 LEU n 
1 314 ILE n 
1 315 ASN n 
1 316 ARG n 
1 317 CYS n 
1 318 LEU n 
1 319 GLN n 
1 320 ARG n 
1 321 LYS n 
1 322 MET n 
1 323 THR n 
1 324 GLY n 
1 325 GLU n 
1 326 PRO n 
1 327 ASP n 
1 328 ASN n 
1 329 ASN n 
1 330 ARG n 
1 331 SER n 
1 332 THR n 
1 333 SER n 
1 334 VAL n 
1 335 GLU n 
1 336 LEU n 
1 337 THR n 
1 338 GLY n 
1 339 ASP n 
1 340 PRO n 
1 341 ASN n 
1 342 LYS n 
1 343 THR n 
1 344 ARG n 
1 345 GLY n 
1 346 ALA n 
1 347 PRO n 
1 348 GLU n 
1 349 ALA n 
1 350 LEU n 
1 351 MET n 
1 352 ALA n 
1 353 ASN n 
1 354 SER n 
1 355 GLY n 
1 356 GLU n 
1 357 PRO n 
1 358 TRP n 
1 359 SER n 
1 360 PRO n 
1 361 SER n 
1 362 TYR n 
1 363 LEU n 
1 364 GLY n 
1 365 PRO n 
1 366 THR n 
1 367 SER n 
1 368 PRO n 
2 1   ASP n 
2 2   VAL n 
2 3   GLN n 
2 4   LEU n 
2 5   VAL n 
2 6   GLU n 
2 7   SER n 
2 8   GLY n 
2 9   GLY n 
2 10  GLY n 
2 11  LEU n 
2 12  VAL n 
2 13  GLN n 
2 14  PRO n 
2 15  GLY n 
2 16  GLY n 
2 17  SER n 
2 18  ARG n 
2 19  LYS n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  SER n 
2 24  ALA n 
2 25  SER n 
2 26  GLY n 
2 27  PHE n 
2 28  ALA n 
2 29  PHE n 
2 30  SER n 
2 31  SER n 
2 32  PHE n 
2 33  GLY n 
2 34  MET n 
2 35  HIS n 
2 36  TRP n 
2 37  VAL n 
2 38  ARG n 
2 39  GLN n 
2 40  ALA n 
2 41  PRO n 
2 42  GLU n 
2 43  LYS n 
2 44  GLY n 
2 45  LEU n 
2 46  GLU n 
2 47  TRP n 
2 48  VAL n 
2 49  ALA n 
2 50  TYR n 
2 51  ILE n 
2 52  SER n 
2 53  SER n 
2 54  GLY n 
2 55  SER n 
2 56  GLY n 
2 57  THR n 
2 58  ILE n 
2 59  TYR n 
2 60  TYR n 
2 61  ALA n 
2 62  ASP n 
2 63  THR n 
2 64  VAL n 
2 65  LYS n 
2 66  GLY n 
2 67  ARG n 
2 68  PHE n 
2 69  THR n 
2 70  ILE n 
2 71  SER n 
2 72  ARG n 
2 73  ASP n 
2 74  ASP n 
2 75  PRO n 
2 76  LYS n 
2 77  ASN n 
2 78  THR n 
2 79  LEU n 
2 80  PHE n 
2 81  LEU n 
2 82  GLN n 
2 83  MET n 
2 84  THR n 
2 85  SER n 
2 86  LEU n 
2 87  ARG n 
2 88  SER n 
2 89  GLU n 
2 90  ASP n 
2 91  THR n 
2 92  ALA n 
2 93  MET n 
2 94  TYR n 
2 95  TYR n 
2 96  CYS n 
2 97  VAL n 
2 98  ARG n 
2 99  SER n 
2 100 ILE n 
2 101 TYR n 
2 102 TYR n 
2 103 TYR n 
2 104 GLY n 
2 105 SER n 
2 106 SER n 
2 107 PRO n 
2 108 PHE n 
2 109 ASP n 
2 110 PHE n 
2 111 TRP n 
2 112 GLY n 
2 113 GLN n 
2 114 GLY n 
2 115 THR n 
2 116 THR n 
2 117 LEU n 
2 118 THR n 
2 119 VAL n 
2 120 SER n 
2 121 SER n 
2 122 GLY n 
2 123 GLY n 
2 124 GLY n 
2 125 GLY n 
2 126 SER n 
2 127 GLY n 
2 128 GLY n 
2 129 GLY n 
2 130 GLY n 
2 131 SER n 
2 132 GLY n 
2 133 GLY n 
2 134 GLY n 
2 135 GLY n 
2 136 SER n 
2 137 ASP n 
2 138 ILE n 
2 139 VAL n 
2 140 MET n 
2 141 THR n 
2 142 GLN n 
2 143 ALA n 
2 144 THR n 
2 145 SER n 
2 146 SER n 
2 147 VAL n 
2 148 PRO n 
2 149 VAL n 
2 150 THR n 
2 151 PRO n 
2 152 GLY n 
2 153 GLU n 
2 154 SER n 
2 155 VAL n 
2 156 SER n 
2 157 ILE n 
2 158 SER n 
2 159 CYS n 
2 160 ARG n 
2 161 SER n 
2 162 SER n 
2 163 LYS n 
2 164 SER n 
2 165 LEU n 
2 166 LEU n 
2 167 HIS n 
2 168 SER n 
2 169 ASN n 
2 170 GLY n 
2 171 ASN n 
2 172 THR n 
2 173 TYR n 
2 174 LEU n 
2 175 TYR n 
2 176 TRP n 
2 177 PHE n 
2 178 LEU n 
2 179 GLN n 
2 180 ARG n 
2 181 PRO n 
2 182 GLY n 
2 183 GLN n 
2 184 SER n 
2 185 PRO n 
2 186 GLN n 
2 187 LEU n 
2 188 LEU n 
2 189 ILE n 
2 190 TYR n 
2 191 ARG n 
2 192 MET n 
2 193 SER n 
2 194 ASN n 
2 195 LEU n 
2 196 ALA n 
2 197 SER n 
2 198 GLY n 
2 199 VAL n 
2 200 PRO n 
2 201 ASP n 
2 202 ARG n 
2 203 PHE n 
2 204 SER n 
2 205 GLY n 
2 206 SER n 
2 207 GLY n 
2 208 SER n 
2 209 GLY n 
2 210 THR n 
2 211 ALA n 
2 212 PHE n 
2 213 THR n 
2 214 LEU n 
2 215 THR n 
2 216 ILE n 
2 217 SER n 
2 218 ARG n 
2 219 LEU n 
2 220 GLU n 
2 221 ALA n 
2 222 GLU n 
2 223 ASP n 
2 224 VAL n 
2 225 GLY n 
2 226 VAL n 
2 227 TYR n 
2 228 TYR n 
2 229 CYS n 
2 230 MET n 
2 231 GLN n 
2 232 HIS n 
2 233 LEU n 
2 234 GLU n 
2 235 TYR n 
2 236 PRO n 
2 237 LEU n 
2 238 THR n 
2 239 PHE n 
2 240 GLY n 
2 241 ALA n 
2 242 GLY n 
2 243 THR n 
2 244 LYS n 
2 245 LEU n 
2 246 GLU n 
2 247 LEU n 
2 248 LYS n 
2 249 ALA n 
2 250 ALA n 
2 251 ALA n 
2 252 LEU n 
2 253 GLU n 
2 254 VAL n 
2 255 LEU n 
2 256 PHE n 
2 257 GLN n 
2 258 GLY n 
2 259 PRO n 
2 260 HIS n 
2 261 HIS n 
2 262 HIS n 
2 263 HIS n 
2 264 HIS n 
2 265 HIS n 
2 266 HIS n 
2 267 HIS n 
3 1   MET n 
3 2   GLY n 
3 3   CYS n 
3 4   THR n 
3 5   LEU n 
3 6   SER n 
3 7   ALA n 
3 8   GLU n 
3 9   ASP n 
3 10  LYS n 
3 11  ALA n 
3 12  ALA n 
3 13  VAL n 
3 14  GLU n 
3 15  ARG n 
3 16  SER n 
3 17  LYS n 
3 18  MET n 
3 19  ILE n 
3 20  ASP n 
3 21  ARG n 
3 22  ASN n 
3 23  LEU n 
3 24  ARG n 
3 25  GLU n 
3 26  ASP n 
3 27  GLY n 
3 28  GLU n 
3 29  LYS n 
3 30  ALA n 
3 31  ALA n 
3 32  ARG n 
3 33  GLU n 
3 34  VAL n 
3 35  LYS n 
3 36  LEU n 
3 37  LEU n 
3 38  LEU n 
3 39  LEU n 
3 40  GLY n 
3 41  ALA n 
3 42  GLY n 
3 43  GLU n 
3 44  SER n 
3 45  GLY n 
3 46  LYS n 
3 47  SER n 
3 48  THR n 
3 49  ILE n 
3 50  VAL n 
3 51  LYS n 
3 52  GLN n 
3 53  MET n 
3 54  LYS n 
3 55  ILE n 
3 56  ILE n 
3 57  HIS n 
3 58  GLU n 
3 59  ALA n 
3 60  GLY n 
3 61  TYR n 
3 62  SER n 
3 63  GLU n 
3 64  GLU n 
3 65  GLU n 
3 66  CYS n 
3 67  LYS n 
3 68  GLN n 
3 69  TYR n 
3 70  LYS n 
3 71  ALA n 
3 72  VAL n 
3 73  VAL n 
3 74  TYR n 
3 75  SER n 
3 76  ASN n 
3 77  THR n 
3 78  ILE n 
3 79  GLN n 
3 80  SER n 
3 81  ILE n 
3 82  ILE n 
3 83  ALA n 
3 84  ILE n 
3 85  ILE n 
3 86  ARG n 
3 87  ALA n 
3 88  MET n 
3 89  GLY n 
3 90  ARG n 
3 91  LEU n 
3 92  LYS n 
3 93  ILE n 
3 94  ASP n 
3 95  PHE n 
3 96  GLY n 
3 97  ASP n 
3 98  SER n 
3 99  ALA n 
3 100 ARG n 
3 101 ALA n 
3 102 ASP n 
3 103 ASP n 
3 104 ALA n 
3 105 ARG n 
3 106 GLN n 
3 107 LEU n 
3 108 PHE n 
3 109 VAL n 
3 110 LEU n 
3 111 ALA n 
3 112 GLY n 
3 113 ALA n 
3 114 ALA n 
3 115 GLU n 
3 116 GLU n 
3 117 GLY n 
3 118 PHE n 
3 119 MET n 
3 120 THR n 
3 121 ALA n 
3 122 GLU n 
3 123 LEU n 
3 124 ALA n 
3 125 GLY n 
3 126 VAL n 
3 127 ILE n 
3 128 LYS n 
3 129 ARG n 
3 130 LEU n 
3 131 TRP n 
3 132 LYS n 
3 133 ASP n 
3 134 SER n 
3 135 GLY n 
3 136 VAL n 
3 137 GLN n 
3 138 ALA n 
3 139 CYS n 
3 140 PHE n 
3 141 ASN n 
3 142 ARG n 
3 143 SER n 
3 144 ARG n 
3 145 GLU n 
3 146 TYR n 
3 147 GLN n 
3 148 LEU n 
3 149 ASN n 
3 150 ASP n 
3 151 SER n 
3 152 ALA n 
3 153 ALA n 
3 154 TYR n 
3 155 TYR n 
3 156 LEU n 
3 157 ASN n 
3 158 ASP n 
3 159 LEU n 
3 160 ASP n 
3 161 ARG n 
3 162 ILE n 
3 163 ALA n 
3 164 GLN n 
3 165 PRO n 
3 166 ASN n 
3 167 TYR n 
3 168 ILE n 
3 169 PRO n 
3 170 THR n 
3 171 GLN n 
3 172 GLN n 
3 173 ASP n 
3 174 VAL n 
3 175 LEU n 
3 176 ARG n 
3 177 THR n 
3 178 ARG n 
3 179 VAL n 
3 180 LYS n 
3 181 THR n 
3 182 THR n 
3 183 GLY n 
3 184 ILE n 
3 185 VAL n 
3 186 GLU n 
3 187 THR n 
3 188 HIS n 
3 189 PHE n 
3 190 THR n 
3 191 PHE n 
3 192 LYS n 
3 193 ASP n 
3 194 LEU n 
3 195 HIS n 
3 196 PHE n 
3 197 LYS n 
3 198 MET n 
3 199 PHE n 
3 200 ASP n 
3 201 VAL n 
3 202 GLY n 
3 203 ALA n 
3 204 GLN n 
3 205 ARG n 
3 206 SER n 
3 207 GLU n 
3 208 ARG n 
3 209 LYS n 
3 210 LYS n 
3 211 TRP n 
3 212 ILE n 
3 213 HIS n 
3 214 CYS n 
3 215 PHE n 
3 216 GLU n 
3 217 GLY n 
3 218 VAL n 
3 219 THR n 
3 220 ALA n 
3 221 ILE n 
3 222 ILE n 
3 223 PHE n 
3 224 CYS n 
3 225 VAL n 
3 226 ALA n 
3 227 LEU n 
3 228 SER n 
3 229 ASP n 
3 230 TYR n 
3 231 ASP n 
3 232 LEU n 
3 233 VAL n 
3 234 LEU n 
3 235 ALA n 
3 236 GLU n 
3 237 ASP n 
3 238 GLU n 
3 239 GLU n 
3 240 MET n 
3 241 ASN n 
3 242 ARG n 
3 243 MET n 
3 244 HIS n 
3 245 GLU n 
3 246 SER n 
3 247 MET n 
3 248 LYS n 
3 249 LEU n 
3 250 PHE n 
3 251 ASP n 
3 252 SER n 
3 253 ILE n 
3 254 CYS n 
3 255 ASN n 
3 256 ASN n 
3 257 LYS n 
3 258 TRP n 
3 259 PHE n 
3 260 THR n 
3 261 ASP n 
3 262 THR n 
3 263 SER n 
3 264 ILE n 
3 265 ILE n 
3 266 LEU n 
3 267 PHE n 
3 268 LEU n 
3 269 ASN n 
3 270 LYS n 
3 271 LYS n 
3 272 ASP n 
3 273 LEU n 
3 274 PHE n 
3 275 GLU n 
3 276 GLU n 
3 277 LYS n 
3 278 ILE n 
3 279 LYS n 
3 280 LYS n 
3 281 SER n 
3 282 PRO n 
3 283 LEU n 
3 284 THR n 
3 285 ILE n 
3 286 CYS n 
3 287 TYR n 
3 288 PRO n 
3 289 GLU n 
3 290 TYR n 
3 291 ALA n 
3 292 GLY n 
3 293 SER n 
3 294 ASN n 
3 295 THR n 
3 296 TYR n 
3 297 GLU n 
3 298 GLU n 
3 299 ALA n 
3 300 ALA n 
3 301 ALA n 
3 302 TYR n 
3 303 ILE n 
3 304 GLN n 
3 305 CYS n 
3 306 GLN n 
3 307 PHE n 
3 308 GLU n 
3 309 ASP n 
3 310 LEU n 
3 311 ASN n 
3 312 LYS n 
3 313 ARG n 
3 314 LYS n 
3 315 ASP n 
3 316 THR n 
3 317 LYS n 
3 318 GLU n 
3 319 ILE n 
3 320 TYR n 
3 321 THR n 
3 322 HIS n 
3 323 PHE n 
3 324 THR n 
3 325 CYS n 
3 326 SER n 
3 327 THR n 
3 328 ASP n 
3 329 THR n 
3 330 LYS n 
3 331 ASN n 
3 332 VAL n 
3 333 GLN n 
3 334 PHE n 
3 335 VAL n 
3 336 PHE n 
3 337 ASP n 
3 338 ALA n 
3 339 VAL n 
3 340 THR n 
3 341 ASP n 
3 342 VAL n 
3 343 ILE n 
3 344 ILE n 
3 345 LYS n 
3 346 ASN n 
3 347 ASN n 
3 348 LEU n 
3 349 LYS n 
3 350 ASP n 
3 351 CYS n 
3 352 GLY n 
3 353 LEU n 
3 354 PHE n 
4 1   MET n 
4 2   HIS n 
4 3   HIS n 
4 4   HIS n 
4 5   HIS n 
4 6   HIS n 
4 7   HIS n 
4 8   LEU n 
4 9   GLU n 
4 10  VAL n 
4 11  LEU n 
4 12  PHE n 
4 13  GLN n 
4 14  GLY n 
4 15  PRO n 
4 16  GLY n 
4 17  SER n 
4 18  SER n 
4 19  GLY n 
4 20  SER n 
4 21  GLU n 
4 22  LEU n 
4 23  ASP n 
4 24  GLN n 
4 25  LEU n 
4 26  ARG n 
4 27  GLN n 
4 28  GLU n 
4 29  ALA n 
4 30  GLU n 
4 31  GLN n 
4 32  LEU n 
4 33  LYS n 
4 34  ASN n 
4 35  GLN n 
4 36  ILE n 
4 37  ARG n 
4 38  ASP n 
4 39  ALA n 
4 40  ARG n 
4 41  LYS n 
4 42  ALA n 
4 43  CYS n 
4 44  ALA n 
4 45  ASP n 
4 46  ALA n 
4 47  THR n 
4 48  LEU n 
4 49  SER n 
4 50  GLN n 
4 51  ILE n 
4 52  THR n 
4 53  ASN n 
4 54  ASN n 
4 55  ILE n 
4 56  ASP n 
4 57  PRO n 
4 58  VAL n 
4 59  GLY n 
4 60  ARG n 
4 61  ILE n 
4 62  GLN n 
4 63  MET n 
4 64  ARG n 
4 65  THR n 
4 66  ARG n 
4 67  ARG n 
4 68  THR n 
4 69  LEU n 
4 70  ARG n 
4 71  GLY n 
4 72  HIS n 
4 73  LEU n 
4 74  ALA n 
4 75  LYS n 
4 76  ILE n 
4 77  TYR n 
4 78  ALA n 
4 79  MET n 
4 80  HIS n 
4 81  TRP n 
4 82  GLY n 
4 83  THR n 
4 84  ASP n 
4 85  SER n 
4 86  ARG n 
4 87  LEU n 
4 88  LEU n 
4 89  VAL n 
4 90  SER n 
4 91  ALA n 
4 92  SER n 
4 93  GLN n 
4 94  ASP n 
4 95  GLY n 
4 96  LYS n 
4 97  LEU n 
4 98  ILE n 
4 99  ILE n 
4 100 TRP n 
4 101 ASP n 
4 102 SER n 
4 103 TYR n 
4 104 THR n 
4 105 THR n 
4 106 ASN n 
4 107 LYS n 
4 108 VAL n 
4 109 HIS n 
4 110 ALA n 
4 111 ILE n 
4 112 PRO n 
4 113 LEU n 
4 114 ARG n 
4 115 SER n 
4 116 SER n 
4 117 TRP n 
4 118 VAL n 
4 119 MET n 
4 120 THR n 
4 121 CYS n 
4 122 ALA n 
4 123 TYR n 
4 124 ALA n 
4 125 PRO n 
4 126 SER n 
4 127 GLY n 
4 128 ASN n 
4 129 TYR n 
4 130 VAL n 
4 131 ALA n 
4 132 CYS n 
4 133 GLY n 
4 134 GLY n 
4 135 LEU n 
4 136 ASP n 
4 137 ASN n 
4 138 ILE n 
4 139 CYS n 
4 140 SER n 
4 141 ILE n 
4 142 TYR n 
4 143 ASN n 
4 144 LEU n 
4 145 LYS n 
4 146 THR n 
4 147 ARG n 
4 148 GLU n 
4 149 GLY n 
4 150 ASN n 
4 151 VAL n 
4 152 ARG n 
4 153 VAL n 
4 154 SER n 
4 155 ARG n 
4 156 GLU n 
4 157 LEU n 
4 158 ALA n 
4 159 GLY n 
4 160 HIS n 
4 161 THR n 
4 162 GLY n 
4 163 TYR n 
4 164 LEU n 
4 165 SER n 
4 166 CYS n 
4 167 CYS n 
4 168 ARG n 
4 169 PHE n 
4 170 LEU n 
4 171 ASP n 
4 172 ASP n 
4 173 ASN n 
4 174 GLN n 
4 175 ILE n 
4 176 VAL n 
4 177 THR n 
4 178 SER n 
4 179 SER n 
4 180 GLY n 
4 181 ASP n 
4 182 THR n 
4 183 THR n 
4 184 CYS n 
4 185 ALA n 
4 186 LEU n 
4 187 TRP n 
4 188 ASP n 
4 189 ILE n 
4 190 GLU n 
4 191 THR n 
4 192 GLY n 
4 193 GLN n 
4 194 GLN n 
4 195 THR n 
4 196 THR n 
4 197 THR n 
4 198 PHE n 
4 199 THR n 
4 200 GLY n 
4 201 HIS n 
4 202 THR n 
4 203 GLY n 
4 204 ASP n 
4 205 VAL n 
4 206 MET n 
4 207 SER n 
4 208 LEU n 
4 209 SER n 
4 210 LEU n 
4 211 ALA n 
4 212 PRO n 
4 213 ASP n 
4 214 THR n 
4 215 ARG n 
4 216 LEU n 
4 217 PHE n 
4 218 VAL n 
4 219 SER n 
4 220 GLY n 
4 221 ALA n 
4 222 CYS n 
4 223 ASP n 
4 224 ALA n 
4 225 SER n 
4 226 ALA n 
4 227 LYS n 
4 228 LEU n 
4 229 TRP n 
4 230 ASP n 
4 231 VAL n 
4 232 ARG n 
4 233 GLU n 
4 234 GLY n 
4 235 MET n 
4 236 CYS n 
4 237 ARG n 
4 238 GLN n 
4 239 THR n 
4 240 PHE n 
4 241 THR n 
4 242 GLY n 
4 243 HIS n 
4 244 GLU n 
4 245 SER n 
4 246 ASP n 
4 247 ILE n 
4 248 ASN n 
4 249 ALA n 
4 250 ILE n 
4 251 CYS n 
4 252 PHE n 
4 253 PHE n 
4 254 PRO n 
4 255 ASN n 
4 256 GLY n 
4 257 ASN n 
4 258 ALA n 
4 259 PHE n 
4 260 ALA n 
4 261 THR n 
4 262 GLY n 
4 263 SER n 
4 264 ASP n 
4 265 ASP n 
4 266 ALA n 
4 267 THR n 
4 268 CYS n 
4 269 ARG n 
4 270 LEU n 
4 271 PHE n 
4 272 ASP n 
4 273 LEU n 
4 274 ARG n 
4 275 ALA n 
4 276 ASP n 
4 277 GLN n 
4 278 GLU n 
4 279 LEU n 
4 280 MET n 
4 281 THR n 
4 282 TYR n 
4 283 SER n 
4 284 HIS n 
4 285 ASP n 
4 286 ASN n 
4 287 ILE n 
4 288 ILE n 
4 289 CYS n 
4 290 GLY n 
4 291 ILE n 
4 292 THR n 
4 293 SER n 
4 294 VAL n 
4 295 SER n 
4 296 PHE n 
4 297 SER n 
4 298 LYS n 
4 299 SER n 
4 300 GLY n 
4 301 ARG n 
4 302 LEU n 
4 303 LEU n 
4 304 LEU n 
4 305 ALA n 
4 306 GLY n 
4 307 TYR n 
4 308 ASP n 
4 309 ASP n 
4 310 PHE n 
4 311 ASN n 
4 312 CYS n 
4 313 ASN n 
4 314 VAL n 
4 315 TRP n 
4 316 ASP n 
4 317 ALA n 
4 318 LEU n 
4 319 LYS n 
4 320 ALA n 
4 321 ASP n 
4 322 ARG n 
4 323 ALA n 
4 324 GLY n 
4 325 VAL n 
4 326 LEU n 
4 327 ALA n 
4 328 GLY n 
4 329 HIS n 
4 330 ASP n 
4 331 ASN n 
4 332 ARG n 
4 333 VAL n 
4 334 SER n 
4 335 CYS n 
4 336 LEU n 
4 337 GLY n 
4 338 VAL n 
4 339 THR n 
4 340 ASP n 
4 341 ASP n 
4 342 GLY n 
4 343 MET n 
4 344 ALA n 
4 345 VAL n 
4 346 ALA n 
4 347 THR n 
4 348 GLY n 
4 349 SER n 
4 350 TRP n 
4 351 ASP n 
4 352 SER n 
4 353 PHE n 
4 354 LEU n 
4 355 LYS n 
4 356 ILE n 
4 357 TRP n 
4 358 ASN n 
5 1   MET n 
5 2   ALA n 
5 3   SER n 
5 4   ASN n 
5 5   ASN n 
5 6   THR n 
5 7   ALA n 
5 8   SER n 
5 9   ILE n 
5 10  ALA n 
5 11  GLN n 
5 12  ALA n 
5 13  ARG n 
5 14  LYS n 
5 15  LEU n 
5 16  VAL n 
5 17  GLU n 
5 18  GLN n 
5 19  LEU n 
5 20  LYS n 
5 21  MET n 
5 22  GLU n 
5 23  ALA n 
5 24  ASN n 
5 25  ILE n 
5 26  ASP n 
5 27  ARG n 
5 28  ILE n 
5 29  LYS n 
5 30  VAL n 
5 31  SER n 
5 32  LYS n 
5 33  ALA n 
5 34  ALA n 
5 35  ALA n 
5 36  ASP n 
5 37  LEU n 
5 38  MET n 
5 39  ALA n 
5 40  TYR n 
5 41  CYS n 
5 42  GLU n 
5 43  ALA n 
5 44  HIS n 
5 45  ALA n 
5 46  LYS n 
5 47  GLU n 
5 48  ASP n 
5 49  PRO n 
5 50  LEU n 
5 51  LEU n 
5 52  THR n 
5 53  PRO n 
5 54  VAL n 
5 55  PRO n 
5 56  ALA n 
5 57  SER n 
5 58  GLU n 
5 59  ASN n 
5 60  PRO n 
5 61  PHE n 
5 62  ARG n 
5 63  GLU n 
5 64  LYS n 
5 65  LYS n 
5 66  PHE n 
5 67  PHE n 
5 68  CYS n 
5 69  ALA n 
5 70  ILE n 
5 71  LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 368 human ? HCAR2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 267 ?     ? ?     ? ? ? ? ? ? 'Lama glama'   9844 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 354 human ? GNAI1 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 358 human ? GNB1  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1 71  human ? GNG2  ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                        ?         
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                       ?         
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                     ?         
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                ?         
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                       ?         
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                      ?         
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                ?         
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                        ?         
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                      ?         
'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                                                                     ?         
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                        ?         
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                         ?         
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                     ?         
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                  ?         
'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                                                                        ?         
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                         ?         
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                                      ?         
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                     ?         
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                       ?         
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                         ?         
'C5 H11 N O2'    117.146 
XOT non-polymer         . '(4aR,5aR)-4,4a,5,5a-tetrahydro-1H-cyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxylic acid' 'MK 1903' 
'C8 H8 N2 O2'    164.161 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   -4  ?   ?   ?   R . n 
A 1 2   GLY 2   -3  ?   ?   ?   R . n 
A 1 3   GLY 3   -2  ?   ?   ?   R . n 
A 1 4   THR 4   -1  ?   ?   ?   R . n 
A 1 5   THR 5   0   ?   ?   ?   R . n 
A 1 6   MET 6   1   ?   ?   ?   R . n 
A 1 7   ASN 7   2   ?   ?   ?   R . n 
A 1 8   ARG 8   3   ?   ?   ?   R . n 
A 1 9   HIS 9   4   ?   ?   ?   R . n 
A 1 10  HIS 10  5   ?   ?   ?   R . n 
A 1 11  LEU 11  6   ?   ?   ?   R . n 
A 1 12  GLN 12  7   7   GLN GLN R . n 
A 1 13  ASP 13  8   8   ASP ASP R . n 
A 1 14  HIS 14  9   9   HIS HIS R . n 
A 1 15  PHE 15  10  10  PHE PHE R . n 
A 1 16  LEU 16  11  11  LEU LEU R . n 
A 1 17  GLU 17  12  12  GLU GLU R . n 
A 1 18  ILE 18  13  13  ILE ILE R . n 
A 1 19  ASP 19  14  14  ASP ASP R . n 
A 1 20  LYS 20  15  15  LYS LYS R . n 
A 1 21  LYS 21  16  16  LYS LYS R . n 
A 1 22  ASN 22  17  17  ASN ASN R . n 
A 1 23  CYS 23  18  18  CYS CYS R . n 
A 1 24  CYS 24  19  19  CYS CYS R . n 
A 1 25  VAL 25  20  20  VAL VAL R . n 
A 1 26  PHE 26  21  21  PHE PHE R . n 
A 1 27  ARG 27  22  22  ARG ARG R . n 
A 1 28  ASP 28  23  23  ASP ASP R . n 
A 1 29  ASP 29  24  24  ASP ASP R . n 
A 1 30  PHE 30  25  25  PHE PHE R . n 
A 1 31  ILE 31  26  26  ILE ILE R . n 
A 1 32  VAL 32  27  27  VAL VAL R . n 
A 1 33  LYS 33  28  28  LYS LYS R . n 
A 1 34  VAL 34  29  29  VAL VAL R . n 
A 1 35  LEU 35  30  30  LEU LEU R . n 
A 1 36  PRO 36  31  31  PRO PRO R . n 
A 1 37  PRO 37  32  32  PRO PRO R . n 
A 1 38  VAL 38  33  33  VAL VAL R . n 
A 1 39  LEU 39  34  34  LEU LEU R . n 
A 1 40  GLY 40  35  35  GLY GLY R . n 
A 1 41  LEU 41  36  36  LEU LEU R . n 
A 1 42  GLU 42  37  37  GLU GLU R . n 
A 1 43  PHE 43  38  38  PHE PHE R . n 
A 1 44  ILE 44  39  39  ILE ILE R . n 
A 1 45  PHE 45  40  40  PHE PHE R . n 
A 1 46  GLY 46  41  41  GLY GLY R . n 
A 1 47  LEU 47  42  42  LEU LEU R . n 
A 1 48  LEU 48  43  43  LEU LEU R . n 
A 1 49  GLY 49  44  44  GLY GLY R . n 
A 1 50  ASN 50  45  45  ASN ASN R . n 
A 1 51  GLY 51  46  46  GLY GLY R . n 
A 1 52  LEU 52  47  47  LEU LEU R . n 
A 1 53  ALA 53  48  48  ALA ALA R . n 
A 1 54  LEU 54  49  49  LEU LEU R . n 
A 1 55  TRP 55  50  50  TRP TRP R . n 
A 1 56  ILE 56  51  51  ILE ILE R . n 
A 1 57  PHE 57  52  52  PHE PHE R . n 
A 1 58  CYS 58  53  53  CYS CYS R . n 
A 1 59  PHE 59  54  54  PHE PHE R . n 
A 1 60  HIS 60  55  55  HIS HIS R . n 
A 1 61  LEU 61  56  56  LEU LEU R . n 
A 1 62  LYS 62  57  57  LYS LYS R . n 
A 1 63  SER 63  58  58  SER SER R . n 
A 1 64  TRP 64  59  59  TRP TRP R . n 
A 1 65  LYS 65  60  60  LYS LYS R . n 
A 1 66  SER 66  61  61  SER SER R . n 
A 1 67  SER 67  62  62  SER SER R . n 
A 1 68  ARG 68  63  63  ARG ARG R . n 
A 1 69  ILE 69  64  64  ILE ILE R . n 
A 1 70  PHE 70  65  65  PHE PHE R . n 
A 1 71  LEU 71  66  66  LEU LEU R . n 
A 1 72  PHE 72  67  67  PHE PHE R . n 
A 1 73  ASN 73  68  68  ASN ASN R . n 
A 1 74  LEU 74  69  69  LEU LEU R . n 
A 1 75  ALA 75  70  70  ALA ALA R . n 
A 1 76  VAL 76  71  71  VAL VAL R . n 
A 1 77  ALA 77  72  72  ALA ALA R . n 
A 1 78  ASP 78  73  73  ASP ASP R . n 
A 1 79  PHE 79  74  74  PHE PHE R . n 
A 1 80  LEU 80  75  75  LEU LEU R . n 
A 1 81  LEU 81  76  76  LEU LEU R . n 
A 1 82  ILE 82  77  77  ILE ILE R . n 
A 1 83  ILE 83  78  78  ILE ILE R . n 
A 1 84  CYS 84  79  79  CYS CYS R . n 
A 1 85  LEU 85  80  80  LEU LEU R . n 
A 1 86  PRO 86  81  81  PRO PRO R . n 
A 1 87  PHE 87  82  82  PHE PHE R . n 
A 1 88  LEU 88  83  83  LEU LEU R . n 
A 1 89  MET 89  84  84  MET MET R . n 
A 1 90  ASP 90  85  85  ASP ASP R . n 
A 1 91  ASN 91  86  86  ASN ASN R . n 
A 1 92  TYR 92  87  87  TYR TYR R . n 
A 1 93  VAL 93  88  88  VAL VAL R . n 
A 1 94  ARG 94  89  89  ARG ARG R . n 
A 1 95  ARG 95  90  90  ARG ARG R . n 
A 1 96  TRP 96  91  91  TRP TRP R . n 
A 1 97  ASP 97  92  92  ASP ASP R . n 
A 1 98  TRP 98  93  93  TRP TRP R . n 
A 1 99  LYS 99  94  94  LYS LYS R . n 
A 1 100 PHE 100 95  95  PHE PHE R . n 
A 1 101 GLY 101 96  96  GLY GLY R . n 
A 1 102 ASP 102 97  97  ASP ASP R . n 
A 1 103 ILE 103 98  98  ILE ILE R . n 
A 1 104 PRO 104 99  99  PRO PRO R . n 
A 1 105 CYS 105 100 100 CYS CYS R . n 
A 1 106 ARG 106 101 101 ARG ARG R . n 
A 1 107 LEU 107 102 102 LEU LEU R . n 
A 1 108 MET 108 103 103 MET MET R . n 
A 1 109 LEU 109 104 104 LEU LEU R . n 
A 1 110 PHE 110 105 105 PHE PHE R . n 
A 1 111 MET 111 106 106 MET MET R . n 
A 1 112 LEU 112 107 107 LEU LEU R . n 
A 1 113 ALA 113 108 108 ALA ALA R . n 
A 1 114 MET 114 109 109 MET MET R . n 
A 1 115 ASN 115 110 110 ASN ASN R . n 
A 1 116 ARG 116 111 111 ARG ARG R . n 
A 1 117 GLN 117 112 112 GLN GLN R . n 
A 1 118 GLY 118 113 113 GLY GLY R . n 
A 1 119 SER 119 114 114 SER SER R . n 
A 1 120 ILE 120 115 115 ILE ILE R . n 
A 1 121 ILE 121 116 116 ILE ILE R . n 
A 1 122 PHE 122 117 117 PHE PHE R . n 
A 1 123 LEU 123 118 118 LEU LEU R . n 
A 1 124 THR 124 119 119 THR THR R . n 
A 1 125 VAL 125 120 120 VAL VAL R . n 
A 1 126 VAL 126 121 121 VAL VAL R . n 
A 1 127 ALA 127 122 122 ALA ALA R . n 
A 1 128 VAL 128 123 123 VAL VAL R . n 
A 1 129 ALA 129 124 124 ALA ALA R . n 
A 1 130 ARG 130 125 125 ARG ARG R . n 
A 1 131 TYR 131 126 126 TYR TYR R . n 
A 1 132 PHE 132 127 127 PHE PHE R . n 
A 1 133 ARG 133 128 128 ARG ARG R . n 
A 1 134 VAL 134 129 129 VAL VAL R . n 
A 1 135 VAL 135 130 130 VAL VAL R . n 
A 1 136 HIS 136 131 131 HIS HIS R . n 
A 1 137 PRO 137 132 132 PRO PRO R . n 
A 1 138 HIS 138 133 133 HIS HIS R . n 
A 1 139 HIS 139 134 134 HIS HIS R . n 
A 1 140 ALA 140 135 135 ALA ALA R . n 
A 1 141 LEU 141 136 136 LEU LEU R . n 
A 1 142 ASN 142 137 137 ASN ASN R . n 
A 1 143 LYS 143 138 138 LYS LYS R . n 
A 1 144 ILE 144 139 139 ILE ILE R . n 
A 1 145 SER 145 140 140 SER SER R . n 
A 1 146 ASN 146 141 141 ASN ASN R . n 
A 1 147 ARG 147 142 142 ARG ARG R . n 
A 1 148 THR 148 143 143 THR THR R . n 
A 1 149 ALA 149 144 144 ALA ALA R . n 
A 1 150 ALA 150 145 145 ALA ALA R . n 
A 1 151 ILE 151 146 146 ILE ILE R . n 
A 1 152 ILE 152 147 147 ILE ILE R . n 
A 1 153 SER 153 148 148 SER SER R . n 
A 1 154 CYS 154 149 149 CYS CYS R . n 
A 1 155 LEU 155 150 150 LEU LEU R . n 
A 1 156 LEU 156 151 151 LEU LEU R . n 
A 1 157 TRP 157 152 152 TRP TRP R . n 
A 1 158 GLY 158 153 153 GLY GLY R . n 
A 1 159 ILE 159 154 154 ILE ILE R . n 
A 1 160 THR 160 155 155 THR THR R . n 
A 1 161 ILE 161 156 156 ILE ILE R . n 
A 1 162 GLY 162 157 157 GLY GLY R . n 
A 1 163 LEU 163 158 158 LEU LEU R . n 
A 1 164 THR 164 159 159 THR THR R . n 
A 1 165 VAL 165 160 160 VAL VAL R . n 
A 1 166 HIS 166 161 161 HIS HIS R . n 
A 1 167 LEU 167 162 162 LEU LEU R . n 
A 1 168 LEU 168 163 163 LEU LEU R . n 
A 1 169 LYS 169 164 164 LYS LYS R . n 
A 1 170 LYS 170 165 165 LYS LYS R . n 
A 1 171 LYS 171 166 166 LYS LYS R . n 
A 1 172 MET 172 167 167 MET MET R . n 
A 1 173 PRO 173 168 168 PRO PRO R . n 
A 1 174 ILE 174 169 169 ILE ILE R . n 
A 1 175 GLN 175 170 170 GLN GLN R . n 
A 1 176 ASN 176 171 171 ASN ASN R . n 
A 1 177 GLY 177 172 172 GLY GLY R . n 
A 1 178 GLY 178 173 173 GLY GLY R . n 
A 1 179 ALA 179 174 174 ALA ALA R . n 
A 1 180 ASN 180 175 175 ASN ASN R . n 
A 1 181 LEU 181 176 176 LEU LEU R . n 
A 1 182 CYS 182 177 177 CYS CYS R . n 
A 1 183 SER 183 178 178 SER SER R . n 
A 1 184 SER 184 179 179 SER SER R . n 
A 1 185 PHE 185 180 180 PHE PHE R . n 
A 1 186 SER 186 181 181 SER SER R . n 
A 1 187 ILE 187 182 182 ILE ILE R . n 
A 1 188 CYS 188 183 183 CYS CYS R . n 
A 1 189 HIS 189 184 184 HIS HIS R . n 
A 1 190 THR 190 185 185 THR THR R . n 
A 1 191 PHE 191 186 186 PHE PHE R . n 
A 1 192 GLN 192 187 187 GLN GLN R . n 
A 1 193 TRP 193 188 188 TRP TRP R . n 
A 1 194 HIS 194 189 189 HIS HIS R . n 
A 1 195 GLU 195 190 190 GLU GLU R . n 
A 1 196 ALA 196 191 191 ALA ALA R . n 
A 1 197 MET 197 192 192 MET MET R . n 
A 1 198 PHE 198 193 193 PHE PHE R . n 
A 1 199 LEU 199 194 194 LEU LEU R . n 
A 1 200 LEU 200 195 195 LEU LEU R . n 
A 1 201 GLU 201 196 196 GLU GLU R . n 
A 1 202 PHE 202 197 197 PHE PHE R . n 
A 1 203 PHE 203 198 198 PHE PHE R . n 
A 1 204 LEU 204 199 199 LEU LEU R . n 
A 1 205 PRO 205 200 200 PRO PRO R . n 
A 1 206 LEU 206 201 201 LEU LEU R . n 
A 1 207 GLY 207 202 202 GLY GLY R . n 
A 1 208 ILE 208 203 203 ILE ILE R . n 
A 1 209 ILE 209 204 204 ILE ILE R . n 
A 1 210 LEU 210 205 205 LEU LEU R . n 
A 1 211 PHE 211 206 206 PHE PHE R . n 
A 1 212 CYS 212 207 207 CYS CYS R . n 
A 1 213 SER 213 208 208 SER SER R . n 
A 1 214 ALA 214 209 209 ALA ALA R . n 
A 1 215 ARG 215 210 210 ARG ARG R . n 
A 1 216 ILE 216 211 211 ILE ILE R . n 
A 1 217 ILE 217 212 212 ILE ILE R . n 
A 1 218 TRP 218 213 213 TRP TRP R . n 
A 1 219 SER 219 214 214 SER SER R . n 
A 1 220 LEU 220 215 215 LEU LEU R . n 
A 1 221 ARG 221 216 216 ARG ARG R . n 
A 1 222 GLN 222 217 217 GLN GLN R . n 
A 1 223 ARG 223 218 218 ARG ARG R . n 
A 1 224 GLN 224 219 219 GLN GLN R . n 
A 1 225 MET 225 220 220 MET MET R . n 
A 1 226 ASP 226 221 221 ASP ASP R . n 
A 1 227 ARG 227 222 222 ARG ARG R . n 
A 1 228 HIS 228 223 223 HIS HIS R . n 
A 1 229 ALA 229 224 224 ALA ALA R . n 
A 1 230 LYS 230 225 225 LYS LYS R . n 
A 1 231 ILE 231 226 226 ILE ILE R . n 
A 1 232 LYS 232 227 227 LYS LYS R . n 
A 1 233 ARG 233 228 228 ARG ARG R . n 
A 1 234 ALA 234 229 229 ALA ALA R . n 
A 1 235 ILE 235 230 230 ILE ILE R . n 
A 1 236 THR 236 231 231 THR THR R . n 
A 1 237 PHE 237 232 232 PHE PHE R . n 
A 1 238 ILE 238 233 233 ILE ILE R . n 
A 1 239 MET 239 234 234 MET MET R . n 
A 1 240 VAL 240 235 235 VAL VAL R . n 
A 1 241 VAL 241 236 236 VAL VAL R . n 
A 1 242 ALA 242 237 237 ALA ALA R . n 
A 1 243 ILE 243 238 238 ILE ILE R . n 
A 1 244 VAL 244 239 239 VAL VAL R . n 
A 1 245 PHE 245 240 240 PHE PHE R . n 
A 1 246 VAL 246 241 241 VAL VAL R . n 
A 1 247 ILE 247 242 242 ILE ILE R . n 
A 1 248 CYS 248 243 243 CYS CYS R . n 
A 1 249 PHE 249 244 244 PHE PHE R . n 
A 1 250 LEU 250 245 245 LEU LEU R . n 
A 1 251 PRO 251 246 246 PRO PRO R . n 
A 1 252 SER 252 247 247 SER SER R . n 
A 1 253 VAL 253 248 248 VAL VAL R . n 
A 1 254 VAL 254 249 249 VAL VAL R . n 
A 1 255 VAL 255 250 250 VAL VAL R . n 
A 1 256 ARG 256 251 251 ARG ARG R . n 
A 1 257 ILE 257 252 252 ILE ILE R . n 
A 1 258 ARG 258 253 253 ARG ARG R . n 
A 1 259 ILE 259 254 254 ILE ILE R . n 
A 1 260 PHE 260 255 255 PHE PHE R . n 
A 1 261 TRP 261 256 256 TRP TRP R . n 
A 1 262 LEU 262 257 257 LEU LEU R . n 
A 1 263 LEU 263 258 258 LEU LEU R . n 
A 1 264 HIS 264 259 259 HIS HIS R . n 
A 1 265 THR 265 260 260 THR THR R . n 
A 1 266 SER 266 261 261 SER SER R . n 
A 1 267 GLY 267 262 262 GLY GLY R . n 
A 1 268 THR 268 263 263 THR THR R . n 
A 1 269 GLN 269 264 264 GLN GLN R . n 
A 1 270 ASN 270 265 265 ASN ASN R . n 
A 1 271 CYS 271 266 266 CYS CYS R . n 
A 1 272 GLU 272 267 267 GLU GLU R . n 
A 1 273 VAL 273 268 268 VAL VAL R . n 
A 1 274 TYR 274 269 269 TYR TYR R . n 
A 1 275 ARG 275 270 270 ARG ARG R . n 
A 1 276 SER 276 271 271 SER SER R . n 
A 1 277 VAL 277 272 272 VAL VAL R . n 
A 1 278 ASP 278 273 273 ASP ASP R . n 
A 1 279 LEU 279 274 274 LEU LEU R . n 
A 1 280 ALA 280 275 275 ALA ALA R . n 
A 1 281 PHE 281 276 276 PHE PHE R . n 
A 1 282 PHE 282 277 277 PHE PHE R . n 
A 1 283 ILE 283 278 278 ILE ILE R . n 
A 1 284 THR 284 279 279 THR THR R . n 
A 1 285 LEU 285 280 280 LEU LEU R . n 
A 1 286 SER 286 281 281 SER SER R . n 
A 1 287 PHE 287 282 282 PHE PHE R . n 
A 1 288 THR 288 283 283 THR THR R . n 
A 1 289 TYR 289 284 284 TYR TYR R . n 
A 1 290 MET 290 285 285 MET MET R . n 
A 1 291 ASN 291 286 286 ASN ASN R . n 
A 1 292 SER 292 287 287 SER SER R . n 
A 1 293 MET 293 288 288 MET MET R . n 
A 1 294 LEU 294 289 289 LEU LEU R . n 
A 1 295 ASP 295 290 290 ASP ASP R . n 
A 1 296 PRO 296 291 291 PRO PRO R . n 
A 1 297 VAL 297 292 292 VAL VAL R . n 
A 1 298 VAL 298 293 293 VAL VAL R . n 
A 1 299 TYR 299 294 294 TYR TYR R . n 
A 1 300 TYR 300 295 295 TYR TYR R . n 
A 1 301 PHE 301 296 296 PHE PHE R . n 
A 1 302 SER 302 297 297 SER SER R . n 
A 1 303 SER 303 298 298 SER SER R . n 
A 1 304 PRO 304 299 ?   ?   ?   R . n 
A 1 305 SER 305 300 ?   ?   ?   R . n 
A 1 306 PHE 306 301 ?   ?   ?   R . n 
A 1 307 PRO 307 302 ?   ?   ?   R . n 
A 1 308 ASN 308 303 ?   ?   ?   R . n 
A 1 309 PHE 309 304 ?   ?   ?   R . n 
A 1 310 PHE 310 305 ?   ?   ?   R . n 
A 1 311 SER 311 306 ?   ?   ?   R . n 
A 1 312 THR 312 307 ?   ?   ?   R . n 
A 1 313 LEU 313 308 ?   ?   ?   R . n 
A 1 314 ILE 314 309 ?   ?   ?   R . n 
A 1 315 ASN 315 310 ?   ?   ?   R . n 
A 1 316 ARG 316 311 ?   ?   ?   R . n 
A 1 317 CYS 317 312 ?   ?   ?   R . n 
A 1 318 LEU 318 313 ?   ?   ?   R . n 
A 1 319 GLN 319 314 ?   ?   ?   R . n 
A 1 320 ARG 320 315 ?   ?   ?   R . n 
A 1 321 LYS 321 316 ?   ?   ?   R . n 
A 1 322 MET 322 317 ?   ?   ?   R . n 
A 1 323 THR 323 318 ?   ?   ?   R . n 
A 1 324 GLY 324 319 ?   ?   ?   R . n 
A 1 325 GLU 325 320 ?   ?   ?   R . n 
A 1 326 PRO 326 321 ?   ?   ?   R . n 
A 1 327 ASP 327 322 ?   ?   ?   R . n 
A 1 328 ASN 328 323 ?   ?   ?   R . n 
A 1 329 ASN 329 324 ?   ?   ?   R . n 
A 1 330 ARG 330 325 ?   ?   ?   R . n 
A 1 331 SER 331 326 ?   ?   ?   R . n 
A 1 332 THR 332 327 ?   ?   ?   R . n 
A 1 333 SER 333 328 ?   ?   ?   R . n 
A 1 334 VAL 334 329 ?   ?   ?   R . n 
A 1 335 GLU 335 330 ?   ?   ?   R . n 
A 1 336 LEU 336 331 ?   ?   ?   R . n 
A 1 337 THR 337 332 ?   ?   ?   R . n 
A 1 338 GLY 338 333 ?   ?   ?   R . n 
A 1 339 ASP 339 334 ?   ?   ?   R . n 
A 1 340 PRO 340 335 ?   ?   ?   R . n 
A 1 341 ASN 341 336 ?   ?   ?   R . n 
A 1 342 LYS 342 337 ?   ?   ?   R . n 
A 1 343 THR 343 338 ?   ?   ?   R . n 
A 1 344 ARG 344 339 ?   ?   ?   R . n 
A 1 345 GLY 345 340 ?   ?   ?   R . n 
A 1 346 ALA 346 341 ?   ?   ?   R . n 
A 1 347 PRO 347 342 ?   ?   ?   R . n 
A 1 348 GLU 348 343 ?   ?   ?   R . n 
A 1 349 ALA 349 344 ?   ?   ?   R . n 
A 1 350 LEU 350 345 ?   ?   ?   R . n 
A 1 351 MET 351 346 ?   ?   ?   R . n 
A 1 352 ALA 352 347 ?   ?   ?   R . n 
A 1 353 ASN 353 348 ?   ?   ?   R . n 
A 1 354 SER 354 349 ?   ?   ?   R . n 
A 1 355 GLY 355 350 ?   ?   ?   R . n 
A 1 356 GLU 356 351 ?   ?   ?   R . n 
A 1 357 PRO 357 352 ?   ?   ?   R . n 
A 1 358 TRP 358 353 ?   ?   ?   R . n 
A 1 359 SER 359 354 ?   ?   ?   R . n 
A 1 360 PRO 360 355 ?   ?   ?   R . n 
A 1 361 SER 361 356 ?   ?   ?   R . n 
A 1 362 TYR 362 357 ?   ?   ?   R . n 
A 1 363 LEU 363 358 ?   ?   ?   R . n 
A 1 364 GLY 364 359 ?   ?   ?   R . n 
A 1 365 PRO 365 360 ?   ?   ?   R . n 
A 1 366 THR 366 361 ?   ?   ?   R . n 
A 1 367 SER 367 362 ?   ?   ?   R . n 
A 1 368 PRO 368 363 ?   ?   ?   R . n 
B 2 1   ASP 1   1   ?   ?   ?   D . n 
B 2 2   VAL 2   2   2   VAL VAL D . n 
B 2 3   GLN 3   3   3   GLN GLN D . n 
B 2 4   LEU 4   4   4   LEU LEU D . n 
B 2 5   VAL 5   5   5   VAL VAL D . n 
B 2 6   GLU 6   6   6   GLU GLU D . n 
B 2 7   SER 7   7   7   SER SER D . n 
B 2 8   GLY 8   8   8   GLY GLY D . n 
B 2 9   GLY 9   9   9   GLY GLY D . n 
B 2 10  GLY 10  10  10  GLY GLY D . n 
B 2 11  LEU 11  11  11  LEU LEU D . n 
B 2 12  VAL 12  12  12  VAL VAL D . n 
B 2 13  GLN 13  13  13  GLN GLN D . n 
B 2 14  PRO 14  14  14  PRO PRO D . n 
B 2 15  GLY 15  15  15  GLY GLY D . n 
B 2 16  GLY 16  16  16  GLY GLY D . n 
B 2 17  SER 17  17  17  SER SER D . n 
B 2 18  ARG 18  18  18  ARG ARG D . n 
B 2 19  LYS 19  19  19  LYS LYS D . n 
B 2 20  LEU 20  20  20  LEU LEU D . n 
B 2 21  SER 21  21  21  SER SER D . n 
B 2 22  CYS 22  22  22  CYS CYS D . n 
B 2 23  SER 23  23  23  SER SER D . n 
B 2 24  ALA 24  24  24  ALA ALA D . n 
B 2 25  SER 25  25  25  SER SER D . n 
B 2 26  GLY 26  26  26  GLY GLY D . n 
B 2 27  PHE 27  27  27  PHE PHE D . n 
B 2 28  ALA 28  28  28  ALA ALA D . n 
B 2 29  PHE 29  29  29  PHE PHE D . n 
B 2 30  SER 30  30  30  SER SER D . n 
B 2 31  SER 31  31  31  SER SER D . n 
B 2 32  PHE 32  32  32  PHE PHE D . n 
B 2 33  GLY 33  33  33  GLY GLY D . n 
B 2 34  MET 34  34  34  MET MET D . n 
B 2 35  HIS 35  35  35  HIS HIS D . n 
B 2 36  TRP 36  36  36  TRP TRP D . n 
B 2 37  VAL 37  37  37  VAL VAL D . n 
B 2 38  ARG 38  38  38  ARG ARG D . n 
B 2 39  GLN 39  39  39  GLN GLN D . n 
B 2 40  ALA 40  40  40  ALA ALA D . n 
B 2 41  PRO 41  41  41  PRO PRO D . n 
B 2 42  GLU 42  42  42  GLU GLU D . n 
B 2 43  LYS 43  43  43  LYS LYS D . n 
B 2 44  GLY 44  44  44  GLY GLY D . n 
B 2 45  LEU 45  45  45  LEU LEU D . n 
B 2 46  GLU 46  46  46  GLU GLU D . n 
B 2 47  TRP 47  47  47  TRP TRP D . n 
B 2 48  VAL 48  48  48  VAL VAL D . n 
B 2 49  ALA 49  49  49  ALA ALA D . n 
B 2 50  TYR 50  50  50  TYR TYR D . n 
B 2 51  ILE 51  51  51  ILE ILE D . n 
B 2 52  SER 52  52  52  SER SER D . n 
B 2 53  SER 53  53  53  SER SER D . n 
B 2 54  GLY 54  54  54  GLY GLY D . n 
B 2 55  SER 55  55  55  SER SER D . n 
B 2 56  GLY 56  56  56  GLY GLY D . n 
B 2 57  THR 57  57  57  THR THR D . n 
B 2 58  ILE 58  58  58  ILE ILE D . n 
B 2 59  TYR 59  59  59  TYR TYR D . n 
B 2 60  TYR 60  60  60  TYR TYR D . n 
B 2 61  ALA 61  61  61  ALA ALA D . n 
B 2 62  ASP 62  62  62  ASP ASP D . n 
B 2 63  THR 63  63  63  THR THR D . n 
B 2 64  VAL 64  64  64  VAL VAL D . n 
B 2 65  LYS 65  65  65  LYS LYS D . n 
B 2 66  GLY 66  66  66  GLY GLY D . n 
B 2 67  ARG 67  67  67  ARG ARG D . n 
B 2 68  PHE 68  68  68  PHE PHE D . n 
B 2 69  THR 69  69  69  THR THR D . n 
B 2 70  ILE 70  70  70  ILE ILE D . n 
B 2 71  SER 71  71  71  SER SER D . n 
B 2 72  ARG 72  72  72  ARG ARG D . n 
B 2 73  ASP 73  73  73  ASP ASP D . n 
B 2 74  ASP 74  74  74  ASP ASP D . n 
B 2 75  PRO 75  75  75  PRO PRO D . n 
B 2 76  LYS 76  76  76  LYS LYS D . n 
B 2 77  ASN 77  77  77  ASN ASN D . n 
B 2 78  THR 78  78  78  THR THR D . n 
B 2 79  LEU 79  79  79  LEU LEU D . n 
B 2 80  PHE 80  80  80  PHE PHE D . n 
B 2 81  LEU 81  81  81  LEU LEU D . n 
B 2 82  GLN 82  82  82  GLN GLN D . n 
B 2 83  MET 83  83  83  MET MET D . n 
B 2 84  THR 84  84  84  THR THR D . n 
B 2 85  SER 85  85  85  SER SER D . n 
B 2 86  LEU 86  86  86  LEU LEU D . n 
B 2 87  ARG 87  87  87  ARG ARG D . n 
B 2 88  SER 88  88  88  SER SER D . n 
B 2 89  GLU 89  89  89  GLU GLU D . n 
B 2 90  ASP 90  90  90  ASP ASP D . n 
B 2 91  THR 91  91  91  THR THR D . n 
B 2 92  ALA 92  92  92  ALA ALA D . n 
B 2 93  MET 93  93  93  MET MET D . n 
B 2 94  TYR 94  94  94  TYR TYR D . n 
B 2 95  TYR 95  95  95  TYR TYR D . n 
B 2 96  CYS 96  96  96  CYS CYS D . n 
B 2 97  VAL 97  97  97  VAL VAL D . n 
B 2 98  ARG 98  98  98  ARG ARG D . n 
B 2 99  SER 99  99  99  SER SER D . n 
B 2 100 ILE 100 100 100 ILE ILE D . n 
B 2 101 TYR 101 101 101 TYR TYR D . n 
B 2 102 TYR 102 102 102 TYR TYR D . n 
B 2 103 TYR 103 103 103 TYR TYR D . n 
B 2 104 GLY 104 104 104 GLY GLY D . n 
B 2 105 SER 105 105 105 SER SER D . n 
B 2 106 SER 106 106 106 SER SER D . n 
B 2 107 PRO 107 107 107 PRO PRO D . n 
B 2 108 PHE 108 108 108 PHE PHE D . n 
B 2 109 ASP 109 109 109 ASP ASP D . n 
B 2 110 PHE 110 110 110 PHE PHE D . n 
B 2 111 TRP 111 111 111 TRP TRP D . n 
B 2 112 GLY 112 112 112 GLY GLY D . n 
B 2 113 GLN 113 113 113 GLN GLN D . n 
B 2 114 GLY 114 114 114 GLY GLY D . n 
B 2 115 THR 115 115 115 THR THR D . n 
B 2 116 THR 116 116 116 THR THR D . n 
B 2 117 LEU 117 117 117 LEU LEU D . n 
B 2 118 THR 118 118 118 THR THR D . n 
B 2 119 VAL 119 119 119 VAL VAL D . n 
B 2 120 SER 120 120 120 SER SER D . n 
B 2 121 SER 121 120 ?   ?   ?   D A n 
B 2 122 GLY 122 120 ?   ?   ?   D B n 
B 2 123 GLY 123 120 ?   ?   ?   D C n 
B 2 124 GLY 124 120 ?   ?   ?   D D n 
B 2 125 GLY 125 120 ?   ?   ?   D E n 
B 2 126 SER 126 120 ?   ?   ?   D F n 
B 2 127 GLY 127 120 ?   ?   ?   D G n 
B 2 128 GLY 128 120 ?   ?   ?   D H n 
B 2 129 GLY 129 120 ?   ?   ?   D I n 
B 2 130 GLY 130 120 ?   ?   ?   D J n 
B 2 131 SER 131 120 ?   ?   ?   D K n 
B 2 132 GLY 132 120 ?   ?   ?   D L n 
B 2 133 GLY 133 120 ?   ?   ?   D M n 
B 2 134 GLY 134 120 ?   ?   ?   D N n 
B 2 135 GLY 135 120 ?   ?   ?   D O n 
B 2 136 SER 136 124 124 SER SER D . n 
B 2 137 ASP 137 125 125 ASP ASP D . n 
B 2 138 ILE 138 126 126 ILE ILE D . n 
B 2 139 VAL 139 127 127 VAL VAL D . n 
B 2 140 MET 140 128 128 MET MET D . n 
B 2 141 THR 141 129 129 THR THR D . n 
B 2 142 GLN 142 130 130 GLN GLN D . n 
B 2 143 ALA 143 131 131 ALA ALA D . n 
B 2 144 THR 144 132 132 THR THR D . n 
B 2 145 SER 145 133 133 SER SER D . n 
B 2 146 SER 146 134 134 SER SER D . n 
B 2 147 VAL 147 135 135 VAL VAL D . n 
B 2 148 PRO 148 136 136 PRO PRO D . n 
B 2 149 VAL 149 137 137 VAL VAL D . n 
B 2 150 THR 150 138 138 THR THR D . n 
B 2 151 PRO 151 139 139 PRO PRO D . n 
B 2 152 GLY 152 140 140 GLY GLY D . n 
B 2 153 GLU 153 141 141 GLU GLU D . n 
B 2 154 SER 154 142 142 SER SER D . n 
B 2 155 VAL 155 143 143 VAL VAL D . n 
B 2 156 SER 156 144 144 SER SER D . n 
B 2 157 ILE 157 145 145 ILE ILE D . n 
B 2 158 SER 158 146 146 SER SER D . n 
B 2 159 CYS 159 147 147 CYS CYS D . n 
B 2 160 ARG 160 148 148 ARG ARG D . n 
B 2 161 SER 161 149 149 SER SER D . n 
B 2 162 SER 162 150 150 SER SER D . n 
B 2 163 LYS 163 151 151 LYS LYS D . n 
B 2 164 SER 164 152 152 SER SER D . n 
B 2 165 LEU 165 153 153 LEU LEU D . n 
B 2 166 LEU 166 154 154 LEU LEU D . n 
B 2 167 HIS 167 155 155 HIS HIS D . n 
B 2 168 SER 168 156 156 SER SER D . n 
B 2 169 ASN 169 157 157 ASN ASN D . n 
B 2 170 GLY 170 158 158 GLY GLY D . n 
B 2 171 ASN 171 159 159 ASN ASN D . n 
B 2 172 THR 172 160 160 THR THR D . n 
B 2 173 TYR 173 161 161 TYR TYR D . n 
B 2 174 LEU 174 162 162 LEU LEU D . n 
B 2 175 TYR 175 163 163 TYR TYR D . n 
B 2 176 TRP 176 164 164 TRP TRP D . n 
B 2 177 PHE 177 165 165 PHE PHE D . n 
B 2 178 LEU 178 166 166 LEU LEU D . n 
B 2 179 GLN 179 167 167 GLN GLN D . n 
B 2 180 ARG 180 168 168 ARG ARG D . n 
B 2 181 PRO 181 169 169 PRO PRO D . n 
B 2 182 GLY 182 170 170 GLY GLY D . n 
B 2 183 GLN 183 171 171 GLN GLN D . n 
B 2 184 SER 184 172 172 SER SER D . n 
B 2 185 PRO 185 173 173 PRO PRO D . n 
B 2 186 GLN 186 174 174 GLN GLN D . n 
B 2 187 LEU 187 175 175 LEU LEU D . n 
B 2 188 LEU 188 176 176 LEU LEU D . n 
B 2 189 ILE 189 177 177 ILE ILE D . n 
B 2 190 TYR 190 178 178 TYR TYR D . n 
B 2 191 ARG 191 179 179 ARG ARG D . n 
B 2 192 MET 192 180 180 MET MET D . n 
B 2 193 SER 193 181 181 SER SER D . n 
B 2 194 ASN 194 182 182 ASN ASN D . n 
B 2 195 LEU 195 183 183 LEU LEU D . n 
B 2 196 ALA 196 184 184 ALA ALA D . n 
B 2 197 SER 197 185 185 SER SER D . n 
B 2 198 GLY 198 186 186 GLY GLY D . n 
B 2 199 VAL 199 187 187 VAL VAL D . n 
B 2 200 PRO 200 188 188 PRO PRO D . n 
B 2 201 ASP 201 189 189 ASP ASP D . n 
B 2 202 ARG 202 190 190 ARG ARG D . n 
B 2 203 PHE 203 191 191 PHE PHE D . n 
B 2 204 SER 204 192 192 SER SER D . n 
B 2 205 GLY 205 193 193 GLY GLY D . n 
B 2 206 SER 206 194 194 SER SER D . n 
B 2 207 GLY 207 195 195 GLY GLY D . n 
B 2 208 SER 208 196 196 SER SER D . n 
B 2 209 GLY 209 197 197 GLY GLY D . n 
B 2 210 THR 210 198 198 THR THR D . n 
B 2 211 ALA 211 199 199 ALA ALA D . n 
B 2 212 PHE 212 200 200 PHE PHE D . n 
B 2 213 THR 213 201 201 THR THR D . n 
B 2 214 LEU 214 202 202 LEU LEU D . n 
B 2 215 THR 215 203 203 THR THR D . n 
B 2 216 ILE 216 204 204 ILE ILE D . n 
B 2 217 SER 217 205 205 SER SER D . n 
B 2 218 ARG 218 206 206 ARG ARG D . n 
B 2 219 LEU 219 207 207 LEU LEU D . n 
B 2 220 GLU 220 208 208 GLU GLU D . n 
B 2 221 ALA 221 209 209 ALA ALA D . n 
B 2 222 GLU 222 210 210 GLU GLU D . n 
B 2 223 ASP 223 211 211 ASP ASP D . n 
B 2 224 VAL 224 212 212 VAL VAL D . n 
B 2 225 GLY 225 213 213 GLY GLY D . n 
B 2 226 VAL 226 214 214 VAL VAL D . n 
B 2 227 TYR 227 215 215 TYR TYR D . n 
B 2 228 TYR 228 216 216 TYR TYR D . n 
B 2 229 CYS 229 217 217 CYS CYS D . n 
B 2 230 MET 230 218 218 MET MET D . n 
B 2 231 GLN 231 219 219 GLN GLN D . n 
B 2 232 HIS 232 220 220 HIS HIS D . n 
B 2 233 LEU 233 221 221 LEU LEU D . n 
B 2 234 GLU 234 222 222 GLU GLU D . n 
B 2 235 TYR 235 223 223 TYR TYR D . n 
B 2 236 PRO 236 224 224 PRO PRO D . n 
B 2 237 LEU 237 225 225 LEU LEU D . n 
B 2 238 THR 238 226 226 THR THR D . n 
B 2 239 PHE 239 227 227 PHE PHE D . n 
B 2 240 GLY 240 228 228 GLY GLY D . n 
B 2 241 ALA 241 229 229 ALA ALA D . n 
B 2 242 GLY 242 230 230 GLY GLY D . n 
B 2 243 THR 243 231 231 THR THR D . n 
B 2 244 LYS 244 232 232 LYS LYS D . n 
B 2 245 LEU 245 233 233 LEU LEU D . n 
B 2 246 GLU 246 234 234 GLU GLU D . n 
B 2 247 LEU 247 235 235 LEU LEU D . n 
B 2 248 LYS 248 236 ?   ?   ?   D . n 
B 2 249 ALA 249 237 ?   ?   ?   D . n 
B 2 250 ALA 250 238 ?   ?   ?   D . n 
B 2 251 ALA 251 239 ?   ?   ?   D . n 
B 2 252 LEU 252 240 ?   ?   ?   D . n 
B 2 253 GLU 253 241 ?   ?   ?   D . n 
B 2 254 VAL 254 242 ?   ?   ?   D . n 
B 2 255 LEU 255 243 ?   ?   ?   D . n 
B 2 256 PHE 256 244 ?   ?   ?   D . n 
B 2 257 GLN 257 245 ?   ?   ?   D . n 
B 2 258 GLY 258 246 ?   ?   ?   D . n 
B 2 259 PRO 259 247 ?   ?   ?   D . n 
B 2 260 HIS 260 248 ?   ?   ?   D . n 
B 2 261 HIS 261 249 ?   ?   ?   D . n 
B 2 262 HIS 262 250 ?   ?   ?   D . n 
B 2 263 HIS 263 251 ?   ?   ?   D . n 
B 2 264 HIS 264 252 ?   ?   ?   D . n 
B 2 265 HIS 265 253 ?   ?   ?   D . n 
B 2 266 HIS 266 254 ?   ?   ?   D . n 
B 2 267 HIS 267 255 ?   ?   ?   D . n 
C 3 1   MET 1   1   ?   ?   ?   A . n 
C 3 2   GLY 2   2   ?   ?   ?   A . n 
C 3 3   CYS 3   3   ?   ?   ?   A . n 
C 3 4   THR 4   4   ?   ?   ?   A . n 
C 3 5   LEU 5   5   5   LEU LEU A . n 
C 3 6   SER 6   6   6   SER SER A . n 
C 3 7   ALA 7   7   7   ALA ALA A . n 
C 3 8   GLU 8   8   8   GLU GLU A . n 
C 3 9   ASP 9   9   9   ASP ASP A . n 
C 3 10  LYS 10  10  10  LYS LYS A . n 
C 3 11  ALA 11  11  11  ALA ALA A . n 
C 3 12  ALA 12  12  12  ALA ALA A . n 
C 3 13  VAL 13  13  13  VAL VAL A . n 
C 3 14  GLU 14  14  14  GLU GLU A . n 
C 3 15  ARG 15  15  15  ARG ARG A . n 
C 3 16  SER 16  16  16  SER SER A . n 
C 3 17  LYS 17  17  17  LYS LYS A . n 
C 3 18  MET 18  18  18  MET MET A . n 
C 3 19  ILE 19  19  19  ILE ILE A . n 
C 3 20  ASP 20  20  20  ASP ASP A . n 
C 3 21  ARG 21  21  21  ARG ARG A . n 
C 3 22  ASN 22  22  22  ASN ASN A . n 
C 3 23  LEU 23  23  23  LEU LEU A . n 
C 3 24  ARG 24  24  24  ARG ARG A . n 
C 3 25  GLU 25  25  25  GLU GLU A . n 
C 3 26  ASP 26  26  26  ASP ASP A . n 
C 3 27  GLY 27  27  27  GLY GLY A . n 
C 3 28  GLU 28  28  28  GLU GLU A . n 
C 3 29  LYS 29  29  29  LYS LYS A . n 
C 3 30  ALA 30  30  30  ALA ALA A . n 
C 3 31  ALA 31  31  31  ALA ALA A . n 
C 3 32  ARG 32  32  32  ARG ARG A . n 
C 3 33  GLU 33  33  33  GLU GLU A . n 
C 3 34  VAL 34  34  34  VAL VAL A . n 
C 3 35  LYS 35  35  35  LYS LYS A . n 
C 3 36  LEU 36  36  36  LEU LEU A . n 
C 3 37  LEU 37  37  37  LEU LEU A . n 
C 3 38  LEU 38  38  38  LEU LEU A . n 
C 3 39  LEU 39  39  39  LEU LEU A . n 
C 3 40  GLY 40  40  40  GLY GLY A . n 
C 3 41  ALA 41  41  41  ALA ALA A . n 
C 3 42  GLY 42  42  42  GLY GLY A . n 
C 3 43  GLU 43  43  43  GLU GLU A . n 
C 3 44  SER 44  44  44  SER SER A . n 
C 3 45  GLY 45  45  45  GLY GLY A . n 
C 3 46  LYS 46  46  46  LYS LYS A . n 
C 3 47  SER 47  47  47  SER SER A . n 
C 3 48  THR 48  48  48  THR THR A . n 
C 3 49  ILE 49  49  49  ILE ILE A . n 
C 3 50  VAL 50  50  50  VAL VAL A . n 
C 3 51  LYS 51  51  51  LYS LYS A . n 
C 3 52  GLN 52  52  52  GLN GLN A . n 
C 3 53  MET 53  53  ?   ?   ?   A . n 
C 3 54  LYS 54  54  ?   ?   ?   A . n 
C 3 55  ILE 55  55  ?   ?   ?   A . n 
C 3 56  ILE 56  56  ?   ?   ?   A . n 
C 3 57  HIS 57  57  ?   ?   ?   A . n 
C 3 58  GLU 58  58  ?   ?   ?   A . n 
C 3 59  ALA 59  59  ?   ?   ?   A . n 
C 3 60  GLY 60  60  ?   ?   ?   A . n 
C 3 61  TYR 61  61  ?   ?   ?   A . n 
C 3 62  SER 62  62  ?   ?   ?   A . n 
C 3 63  GLU 63  63  ?   ?   ?   A . n 
C 3 64  GLU 64  64  ?   ?   ?   A . n 
C 3 65  GLU 65  65  ?   ?   ?   A . n 
C 3 66  CYS 66  66  ?   ?   ?   A . n 
C 3 67  LYS 67  67  ?   ?   ?   A . n 
C 3 68  GLN 68  68  ?   ?   ?   A . n 
C 3 69  TYR 69  69  ?   ?   ?   A . n 
C 3 70  LYS 70  70  ?   ?   ?   A . n 
C 3 71  ALA 71  71  ?   ?   ?   A . n 
C 3 72  VAL 72  72  ?   ?   ?   A . n 
C 3 73  VAL 73  73  ?   ?   ?   A . n 
C 3 74  TYR 74  74  ?   ?   ?   A . n 
C 3 75  SER 75  75  ?   ?   ?   A . n 
C 3 76  ASN 76  76  ?   ?   ?   A . n 
C 3 77  THR 77  77  ?   ?   ?   A . n 
C 3 78  ILE 78  78  ?   ?   ?   A . n 
C 3 79  GLN 79  79  ?   ?   ?   A . n 
C 3 80  SER 80  80  ?   ?   ?   A . n 
C 3 81  ILE 81  81  ?   ?   ?   A . n 
C 3 82  ILE 82  82  ?   ?   ?   A . n 
C 3 83  ALA 83  83  ?   ?   ?   A . n 
C 3 84  ILE 84  84  ?   ?   ?   A . n 
C 3 85  ILE 85  85  ?   ?   ?   A . n 
C 3 86  ARG 86  86  ?   ?   ?   A . n 
C 3 87  ALA 87  87  ?   ?   ?   A . n 
C 3 88  MET 88  88  ?   ?   ?   A . n 
C 3 89  GLY 89  89  ?   ?   ?   A . n 
C 3 90  ARG 90  90  ?   ?   ?   A . n 
C 3 91  LEU 91  91  ?   ?   ?   A . n 
C 3 92  LYS 92  92  ?   ?   ?   A . n 
C 3 93  ILE 93  93  ?   ?   ?   A . n 
C 3 94  ASP 94  94  ?   ?   ?   A . n 
C 3 95  PHE 95  95  ?   ?   ?   A . n 
C 3 96  GLY 96  96  ?   ?   ?   A . n 
C 3 97  ASP 97  97  ?   ?   ?   A . n 
C 3 98  SER 98  98  ?   ?   ?   A . n 
C 3 99  ALA 99  99  ?   ?   ?   A . n 
C 3 100 ARG 100 100 ?   ?   ?   A . n 
C 3 101 ALA 101 101 ?   ?   ?   A . n 
C 3 102 ASP 102 102 ?   ?   ?   A . n 
C 3 103 ASP 103 103 ?   ?   ?   A . n 
C 3 104 ALA 104 104 ?   ?   ?   A . n 
C 3 105 ARG 105 105 ?   ?   ?   A . n 
C 3 106 GLN 106 106 ?   ?   ?   A . n 
C 3 107 LEU 107 107 ?   ?   ?   A . n 
C 3 108 PHE 108 108 ?   ?   ?   A . n 
C 3 109 VAL 109 109 ?   ?   ?   A . n 
C 3 110 LEU 110 110 ?   ?   ?   A . n 
C 3 111 ALA 111 111 ?   ?   ?   A . n 
C 3 112 GLY 112 112 ?   ?   ?   A . n 
C 3 113 ALA 113 113 ?   ?   ?   A . n 
C 3 114 ALA 114 114 ?   ?   ?   A . n 
C 3 115 GLU 115 115 ?   ?   ?   A . n 
C 3 116 GLU 116 116 ?   ?   ?   A . n 
C 3 117 GLY 117 117 ?   ?   ?   A . n 
C 3 118 PHE 118 118 ?   ?   ?   A . n 
C 3 119 MET 119 119 ?   ?   ?   A . n 
C 3 120 THR 120 120 ?   ?   ?   A . n 
C 3 121 ALA 121 121 ?   ?   ?   A . n 
C 3 122 GLU 122 122 ?   ?   ?   A . n 
C 3 123 LEU 123 123 ?   ?   ?   A . n 
C 3 124 ALA 124 124 ?   ?   ?   A . n 
C 3 125 GLY 125 125 ?   ?   ?   A . n 
C 3 126 VAL 126 126 ?   ?   ?   A . n 
C 3 127 ILE 127 127 ?   ?   ?   A . n 
C 3 128 LYS 128 128 ?   ?   ?   A . n 
C 3 129 ARG 129 129 ?   ?   ?   A . n 
C 3 130 LEU 130 130 ?   ?   ?   A . n 
C 3 131 TRP 131 131 ?   ?   ?   A . n 
C 3 132 LYS 132 132 ?   ?   ?   A . n 
C 3 133 ASP 133 133 ?   ?   ?   A . n 
C 3 134 SER 134 134 ?   ?   ?   A . n 
C 3 135 GLY 135 135 ?   ?   ?   A . n 
C 3 136 VAL 136 136 ?   ?   ?   A . n 
C 3 137 GLN 137 137 ?   ?   ?   A . n 
C 3 138 ALA 138 138 ?   ?   ?   A . n 
C 3 139 CYS 139 139 ?   ?   ?   A . n 
C 3 140 PHE 140 140 ?   ?   ?   A . n 
C 3 141 ASN 141 141 ?   ?   ?   A . n 
C 3 142 ARG 142 142 ?   ?   ?   A . n 
C 3 143 SER 143 143 ?   ?   ?   A . n 
C 3 144 ARG 144 144 ?   ?   ?   A . n 
C 3 145 GLU 145 145 ?   ?   ?   A . n 
C 3 146 TYR 146 146 ?   ?   ?   A . n 
C 3 147 GLN 147 147 ?   ?   ?   A . n 
C 3 148 LEU 148 148 ?   ?   ?   A . n 
C 3 149 ASN 149 149 ?   ?   ?   A . n 
C 3 150 ASP 150 150 ?   ?   ?   A . n 
C 3 151 SER 151 151 ?   ?   ?   A . n 
C 3 152 ALA 152 152 ?   ?   ?   A . n 
C 3 153 ALA 153 153 ?   ?   ?   A . n 
C 3 154 TYR 154 154 ?   ?   ?   A . n 
C 3 155 TYR 155 155 ?   ?   ?   A . n 
C 3 156 LEU 156 156 ?   ?   ?   A . n 
C 3 157 ASN 157 157 ?   ?   ?   A . n 
C 3 158 ASP 158 158 ?   ?   ?   A . n 
C 3 159 LEU 159 159 ?   ?   ?   A . n 
C 3 160 ASP 160 160 ?   ?   ?   A . n 
C 3 161 ARG 161 161 ?   ?   ?   A . n 
C 3 162 ILE 162 162 ?   ?   ?   A . n 
C 3 163 ALA 163 163 ?   ?   ?   A . n 
C 3 164 GLN 164 164 ?   ?   ?   A . n 
C 3 165 PRO 165 165 ?   ?   ?   A . n 
C 3 166 ASN 166 166 ?   ?   ?   A . n 
C 3 167 TYR 167 167 ?   ?   ?   A . n 
C 3 168 ILE 168 168 ?   ?   ?   A . n 
C 3 169 PRO 169 169 ?   ?   ?   A . n 
C 3 170 THR 170 170 ?   ?   ?   A . n 
C 3 171 GLN 171 171 ?   ?   ?   A . n 
C 3 172 GLN 172 172 ?   ?   ?   A . n 
C 3 173 ASP 173 173 ?   ?   ?   A . n 
C 3 174 VAL 174 174 ?   ?   ?   A . n 
C 3 175 LEU 175 175 ?   ?   ?   A . n 
C 3 176 ARG 176 176 ?   ?   ?   A . n 
C 3 177 THR 177 177 ?   ?   ?   A . n 
C 3 178 ARG 178 178 ?   ?   ?   A . n 
C 3 179 VAL 179 179 ?   ?   ?   A . n 
C 3 180 LYS 180 180 ?   ?   ?   A . n 
C 3 181 THR 181 181 ?   ?   ?   A . n 
C 3 182 THR 182 182 182 THR THR A . n 
C 3 183 GLY 183 183 183 GLY GLY A . n 
C 3 184 ILE 184 184 184 ILE ILE A . n 
C 3 185 VAL 185 185 185 VAL VAL A . n 
C 3 186 GLU 186 186 186 GLU GLU A . n 
C 3 187 THR 187 187 187 THR THR A . n 
C 3 188 HIS 188 188 188 HIS HIS A . n 
C 3 189 PHE 189 189 189 PHE PHE A . n 
C 3 190 THR 190 190 190 THR THR A . n 
C 3 191 PHE 191 191 191 PHE PHE A . n 
C 3 192 LYS 192 192 192 LYS LYS A . n 
C 3 193 ASP 193 193 193 ASP ASP A . n 
C 3 194 LEU 194 194 194 LEU LEU A . n 
C 3 195 HIS 195 195 195 HIS HIS A . n 
C 3 196 PHE 196 196 196 PHE PHE A . n 
C 3 197 LYS 197 197 197 LYS LYS A . n 
C 3 198 MET 198 198 198 MET MET A . n 
C 3 199 PHE 199 199 199 PHE PHE A . n 
C 3 200 ASP 200 200 200 ASP ASP A . n 
C 3 201 VAL 201 201 201 VAL VAL A . n 
C 3 202 GLY 202 202 202 GLY GLY A . n 
C 3 203 ALA 203 203 203 ALA ALA A . n 
C 3 204 GLN 204 204 204 GLN GLN A . n 
C 3 205 ARG 205 205 205 ARG ARG A . n 
C 3 206 SER 206 206 206 SER SER A . n 
C 3 207 GLU 207 207 207 GLU GLU A . n 
C 3 208 ARG 208 208 208 ARG ARG A . n 
C 3 209 LYS 209 209 209 LYS LYS A . n 
C 3 210 LYS 210 210 210 LYS LYS A . n 
C 3 211 TRP 211 211 211 TRP TRP A . n 
C 3 212 ILE 212 212 212 ILE ILE A . n 
C 3 213 HIS 213 213 213 HIS HIS A . n 
C 3 214 CYS 214 214 214 CYS CYS A . n 
C 3 215 PHE 215 215 215 PHE PHE A . n 
C 3 216 GLU 216 216 216 GLU GLU A . n 
C 3 217 GLY 217 217 217 GLY GLY A . n 
C 3 218 VAL 218 218 218 VAL VAL A . n 
C 3 219 THR 219 219 219 THR THR A . n 
C 3 220 ALA 220 220 220 ALA ALA A . n 
C 3 221 ILE 221 221 221 ILE ILE A . n 
C 3 222 ILE 222 222 222 ILE ILE A . n 
C 3 223 PHE 223 223 223 PHE PHE A . n 
C 3 224 CYS 224 224 224 CYS CYS A . n 
C 3 225 VAL 225 225 225 VAL VAL A . n 
C 3 226 ALA 226 226 226 ALA ALA A . n 
C 3 227 LEU 227 227 227 LEU LEU A . n 
C 3 228 SER 228 228 228 SER SER A . n 
C 3 229 ASP 229 229 229 ASP ASP A . n 
C 3 230 TYR 230 230 230 TYR TYR A . n 
C 3 231 ASP 231 231 231 ASP ASP A . n 
C 3 232 LEU 232 232 232 LEU LEU A . n 
C 3 233 VAL 233 233 233 VAL VAL A . n 
C 3 234 LEU 234 234 234 LEU LEU A . n 
C 3 235 ALA 235 235 235 ALA ALA A . n 
C 3 236 GLU 236 236 236 GLU GLU A . n 
C 3 237 ASP 237 237 237 ASP ASP A . n 
C 3 238 GLU 238 238 238 GLU GLU A . n 
C 3 239 GLU 239 239 239 GLU GLU A . n 
C 3 240 MET 240 240 240 MET MET A . n 
C 3 241 ASN 241 241 241 ASN ASN A . n 
C 3 242 ARG 242 242 242 ARG ARG A . n 
C 3 243 MET 243 243 243 MET MET A . n 
C 3 244 HIS 244 244 244 HIS HIS A . n 
C 3 245 GLU 245 245 245 GLU GLU A . n 
C 3 246 SER 246 246 246 SER SER A . n 
C 3 247 MET 247 247 247 MET MET A . n 
C 3 248 LYS 248 248 248 LYS LYS A . n 
C 3 249 LEU 249 249 249 LEU LEU A . n 
C 3 250 PHE 250 250 250 PHE PHE A . n 
C 3 251 ASP 251 251 251 ASP ASP A . n 
C 3 252 SER 252 252 252 SER SER A . n 
C 3 253 ILE 253 253 253 ILE ILE A . n 
C 3 254 CYS 254 254 254 CYS CYS A . n 
C 3 255 ASN 255 255 255 ASN ASN A . n 
C 3 256 ASN 256 256 256 ASN ASN A . n 
C 3 257 LYS 257 257 257 LYS LYS A . n 
C 3 258 TRP 258 258 258 TRP TRP A . n 
C 3 259 PHE 259 259 259 PHE PHE A . n 
C 3 260 THR 260 260 260 THR THR A . n 
C 3 261 ASP 261 261 261 ASP ASP A . n 
C 3 262 THR 262 262 262 THR THR A . n 
C 3 263 SER 263 263 263 SER SER A . n 
C 3 264 ILE 264 264 264 ILE ILE A . n 
C 3 265 ILE 265 265 265 ILE ILE A . n 
C 3 266 LEU 266 266 266 LEU LEU A . n 
C 3 267 PHE 267 267 267 PHE PHE A . n 
C 3 268 LEU 268 268 268 LEU LEU A . n 
C 3 269 ASN 269 269 269 ASN ASN A . n 
C 3 270 LYS 270 270 270 LYS LYS A . n 
C 3 271 LYS 271 271 271 LYS LYS A . n 
C 3 272 ASP 272 272 272 ASP ASP A . n 
C 3 273 LEU 273 273 273 LEU LEU A . n 
C 3 274 PHE 274 274 274 PHE PHE A . n 
C 3 275 GLU 275 275 275 GLU GLU A . n 
C 3 276 GLU 276 276 276 GLU GLU A . n 
C 3 277 LYS 277 277 277 LYS LYS A . n 
C 3 278 ILE 278 278 278 ILE ILE A . n 
C 3 279 LYS 279 279 279 LYS LYS A . n 
C 3 280 LYS 280 280 280 LYS LYS A . n 
C 3 281 SER 281 281 281 SER SER A . n 
C 3 282 PRO 282 282 282 PRO PRO A . n 
C 3 283 LEU 283 283 283 LEU LEU A . n 
C 3 284 THR 284 284 284 THR THR A . n 
C 3 285 ILE 285 285 285 ILE ILE A . n 
C 3 286 CYS 286 286 286 CYS CYS A . n 
C 3 287 TYR 287 287 287 TYR TYR A . n 
C 3 288 PRO 288 288 288 PRO PRO A . n 
C 3 289 GLU 289 289 289 GLU GLU A . n 
C 3 290 TYR 290 290 290 TYR TYR A . n 
C 3 291 ALA 291 291 291 ALA ALA A . n 
C 3 292 GLY 292 292 292 GLY GLY A . n 
C 3 293 SER 293 293 293 SER SER A . n 
C 3 294 ASN 294 294 294 ASN ASN A . n 
C 3 295 THR 295 295 295 THR THR A . n 
C 3 296 TYR 296 296 296 TYR TYR A . n 
C 3 297 GLU 297 297 297 GLU GLU A . n 
C 3 298 GLU 298 298 298 GLU GLU A . n 
C 3 299 ALA 299 299 299 ALA ALA A . n 
C 3 300 ALA 300 300 300 ALA ALA A . n 
C 3 301 ALA 301 301 301 ALA ALA A . n 
C 3 302 TYR 302 302 302 TYR TYR A . n 
C 3 303 ILE 303 303 303 ILE ILE A . n 
C 3 304 GLN 304 304 304 GLN GLN A . n 
C 3 305 CYS 305 305 305 CYS CYS A . n 
C 3 306 GLN 306 306 306 GLN GLN A . n 
C 3 307 PHE 307 307 307 PHE PHE A . n 
C 3 308 GLU 308 308 308 GLU GLU A . n 
C 3 309 ASP 309 309 309 ASP ASP A . n 
C 3 310 LEU 310 310 310 LEU LEU A . n 
C 3 311 ASN 311 311 311 ASN ASN A . n 
C 3 312 LYS 312 312 312 LYS LYS A . n 
C 3 313 ARG 313 313 313 ARG ARG A . n 
C 3 314 LYS 314 314 314 LYS LYS A . n 
C 3 315 ASP 315 315 315 ASP ASP A . n 
C 3 316 THR 316 316 316 THR THR A . n 
C 3 317 LYS 317 317 317 LYS LYS A . n 
C 3 318 GLU 318 318 318 GLU GLU A . n 
C 3 319 ILE 319 319 319 ILE ILE A . n 
C 3 320 TYR 320 320 320 TYR TYR A . n 
C 3 321 THR 321 321 321 THR THR A . n 
C 3 322 HIS 322 322 322 HIS HIS A . n 
C 3 323 PHE 323 323 323 PHE PHE A . n 
C 3 324 THR 324 324 324 THR THR A . n 
C 3 325 CYS 325 325 325 CYS CYS A . n 
C 3 326 SER 326 326 326 SER SER A . n 
C 3 327 THR 327 327 327 THR THR A . n 
C 3 328 ASP 328 328 328 ASP ASP A . n 
C 3 329 THR 329 329 329 THR THR A . n 
C 3 330 LYS 330 330 330 LYS LYS A . n 
C 3 331 ASN 331 331 331 ASN ASN A . n 
C 3 332 VAL 332 332 332 VAL VAL A . n 
C 3 333 GLN 333 333 333 GLN GLN A . n 
C 3 334 PHE 334 334 334 PHE PHE A . n 
C 3 335 VAL 335 335 335 VAL VAL A . n 
C 3 336 PHE 336 336 336 PHE PHE A . n 
C 3 337 ASP 337 337 337 ASP ASP A . n 
C 3 338 ALA 338 338 338 ALA ALA A . n 
C 3 339 VAL 339 339 339 VAL VAL A . n 
C 3 340 THR 340 340 340 THR THR A . n 
C 3 341 ASP 341 341 341 ASP ASP A . n 
C 3 342 VAL 342 342 342 VAL VAL A . n 
C 3 343 ILE 343 343 343 ILE ILE A . n 
C 3 344 ILE 344 344 344 ILE ILE A . n 
C 3 345 LYS 345 345 345 LYS LYS A . n 
C 3 346 ASN 346 346 346 ASN ASN A . n 
C 3 347 ASN 347 347 347 ASN ASN A . n 
C 3 348 LEU 348 348 348 LEU LEU A . n 
C 3 349 LYS 349 349 349 LYS LYS A . n 
C 3 350 ASP 350 350 350 ASP ASP A . n 
C 3 351 CYS 351 351 351 CYS CYS A . n 
C 3 352 GLY 352 352 352 GLY GLY A . n 
C 3 353 LEU 353 353 353 LEU LEU A . n 
C 3 354 PHE 354 354 354 PHE PHE A . n 
D 4 1   MET 1   -17 ?   ?   ?   B . n 
D 4 2   HIS 2   -16 ?   ?   ?   B . n 
D 4 3   HIS 3   -15 ?   ?   ?   B . n 
D 4 4   HIS 4   -14 ?   ?   ?   B . n 
D 4 5   HIS 5   -13 ?   ?   ?   B . n 
D 4 6   HIS 6   -12 ?   ?   ?   B . n 
D 4 7   HIS 7   -11 ?   ?   ?   B . n 
D 4 8   LEU 8   -10 ?   ?   ?   B . n 
D 4 9   GLU 9   -9  ?   ?   ?   B . n 
D 4 10  VAL 10  -8  ?   ?   ?   B . n 
D 4 11  LEU 11  -7  ?   ?   ?   B . n 
D 4 12  PHE 12  -6  ?   ?   ?   B . n 
D 4 13  GLN 13  -5  ?   ?   ?   B . n 
D 4 14  GLY 14  -4  ?   ?   ?   B . n 
D 4 15  PRO 15  -3  ?   ?   ?   B . n 
D 4 16  GLY 16  -2  ?   ?   ?   B . n 
D 4 17  SER 17  -1  ?   ?   ?   B . n 
D 4 18  SER 18  0   ?   ?   ?   B . n 
D 4 19  GLY 19  1   ?   ?   ?   B . n 
D 4 20  SER 20  2   ?   ?   ?   B . n 
D 4 21  GLU 21  3   3   GLU GLU B . n 
D 4 22  LEU 22  4   4   LEU LEU B . n 
D 4 23  ASP 23  5   5   ASP ASP B . n 
D 4 24  GLN 24  6   6   GLN GLN B . n 
D 4 25  LEU 25  7   7   LEU LEU B . n 
D 4 26  ARG 26  8   8   ARG ARG B . n 
D 4 27  GLN 27  9   9   GLN GLN B . n 
D 4 28  GLU 28  10  10  GLU GLU B . n 
D 4 29  ALA 29  11  11  ALA ALA B . n 
D 4 30  GLU 30  12  12  GLU GLU B . n 
D 4 31  GLN 31  13  13  GLN GLN B . n 
D 4 32  LEU 32  14  14  LEU LEU B . n 
D 4 33  LYS 33  15  15  LYS LYS B . n 
D 4 34  ASN 34  16  16  ASN ASN B . n 
D 4 35  GLN 35  17  17  GLN GLN B . n 
D 4 36  ILE 36  18  18  ILE ILE B . n 
D 4 37  ARG 37  19  19  ARG ARG B . n 
D 4 38  ASP 38  20  20  ASP ASP B . n 
D 4 39  ALA 39  21  21  ALA ALA B . n 
D 4 40  ARG 40  22  22  ARG ARG B . n 
D 4 41  LYS 41  23  23  LYS LYS B . n 
D 4 42  ALA 42  24  24  ALA ALA B . n 
D 4 43  CYS 43  25  25  CYS CYS B . n 
D 4 44  ALA 44  26  26  ALA ALA B . n 
D 4 45  ASP 45  27  27  ASP ASP B . n 
D 4 46  ALA 46  28  28  ALA ALA B . n 
D 4 47  THR 47  29  29  THR THR B . n 
D 4 48  LEU 48  30  30  LEU LEU B . n 
D 4 49  SER 49  31  31  SER SER B . n 
D 4 50  GLN 50  32  32  GLN GLN B . n 
D 4 51  ILE 51  33  33  ILE ILE B . n 
D 4 52  THR 52  34  34  THR THR B . n 
D 4 53  ASN 53  35  35  ASN ASN B . n 
D 4 54  ASN 54  36  36  ASN ASN B . n 
D 4 55  ILE 55  37  37  ILE ILE B . n 
D 4 56  ASP 56  38  38  ASP ASP B . n 
D 4 57  PRO 57  39  39  PRO PRO B . n 
D 4 58  VAL 58  40  40  VAL VAL B . n 
D 4 59  GLY 59  41  41  GLY GLY B . n 
D 4 60  ARG 60  42  42  ARG ARG B . n 
D 4 61  ILE 61  43  43  ILE ILE B . n 
D 4 62  GLN 62  44  44  GLN GLN B . n 
D 4 63  MET 63  45  45  MET MET B . n 
D 4 64  ARG 64  46  46  ARG ARG B . n 
D 4 65  THR 65  47  47  THR THR B . n 
D 4 66  ARG 66  48  48  ARG ARG B . n 
D 4 67  ARG 67  49  49  ARG ARG B . n 
D 4 68  THR 68  50  50  THR THR B . n 
D 4 69  LEU 69  51  51  LEU LEU B . n 
D 4 70  ARG 70  52  52  ARG ARG B . n 
D 4 71  GLY 71  53  53  GLY GLY B . n 
D 4 72  HIS 72  54  54  HIS HIS B . n 
D 4 73  LEU 73  55  55  LEU LEU B . n 
D 4 74  ALA 74  56  56  ALA ALA B . n 
D 4 75  LYS 75  57  57  LYS LYS B . n 
D 4 76  ILE 76  58  58  ILE ILE B . n 
D 4 77  TYR 77  59  59  TYR TYR B . n 
D 4 78  ALA 78  60  60  ALA ALA B . n 
D 4 79  MET 79  61  61  MET MET B . n 
D 4 80  HIS 80  62  62  HIS HIS B . n 
D 4 81  TRP 81  63  63  TRP TRP B . n 
D 4 82  GLY 82  64  64  GLY GLY B . n 
D 4 83  THR 83  65  65  THR THR B . n 
D 4 84  ASP 84  66  66  ASP ASP B . n 
D 4 85  SER 85  67  67  SER SER B . n 
D 4 86  ARG 86  68  68  ARG ARG B . n 
D 4 87  LEU 87  69  69  LEU LEU B . n 
D 4 88  LEU 88  70  70  LEU LEU B . n 
D 4 89  VAL 89  71  71  VAL VAL B . n 
D 4 90  SER 90  72  72  SER SER B . n 
D 4 91  ALA 91  73  73  ALA ALA B . n 
D 4 92  SER 92  74  74  SER SER B . n 
D 4 93  GLN 93  75  75  GLN GLN B . n 
D 4 94  ASP 94  76  76  ASP ASP B . n 
D 4 95  GLY 95  77  77  GLY GLY B . n 
D 4 96  LYS 96  78  78  LYS LYS B . n 
D 4 97  LEU 97  79  79  LEU LEU B . n 
D 4 98  ILE 98  80  80  ILE ILE B . n 
D 4 99  ILE 99  81  81  ILE ILE B . n 
D 4 100 TRP 100 82  82  TRP TRP B . n 
D 4 101 ASP 101 83  83  ASP ASP B . n 
D 4 102 SER 102 84  84  SER SER B . n 
D 4 103 TYR 103 85  85  TYR TYR B . n 
D 4 104 THR 104 86  86  THR THR B . n 
D 4 105 THR 105 87  87  THR THR B . n 
D 4 106 ASN 106 88  88  ASN ASN B . n 
D 4 107 LYS 107 89  89  LYS LYS B . n 
D 4 108 VAL 108 90  90  VAL VAL B . n 
D 4 109 HIS 109 91  91  HIS HIS B . n 
D 4 110 ALA 110 92  92  ALA ALA B . n 
D 4 111 ILE 111 93  93  ILE ILE B . n 
D 4 112 PRO 112 94  94  PRO PRO B . n 
D 4 113 LEU 113 95  95  LEU LEU B . n 
D 4 114 ARG 114 96  96  ARG ARG B . n 
D 4 115 SER 115 97  97  SER SER B . n 
D 4 116 SER 116 98  98  SER SER B . n 
D 4 117 TRP 117 99  99  TRP TRP B . n 
D 4 118 VAL 118 100 100 VAL VAL B . n 
D 4 119 MET 119 101 101 MET MET B . n 
D 4 120 THR 120 102 102 THR THR B . n 
D 4 121 CYS 121 103 103 CYS CYS B . n 
D 4 122 ALA 122 104 104 ALA ALA B . n 
D 4 123 TYR 123 105 105 TYR TYR B . n 
D 4 124 ALA 124 106 106 ALA ALA B . n 
D 4 125 PRO 125 107 107 PRO PRO B . n 
D 4 126 SER 126 108 108 SER SER B . n 
D 4 127 GLY 127 109 109 GLY GLY B . n 
D 4 128 ASN 128 110 110 ASN ASN B . n 
D 4 129 TYR 129 111 111 TYR TYR B . n 
D 4 130 VAL 130 112 112 VAL VAL B . n 
D 4 131 ALA 131 113 113 ALA ALA B . n 
D 4 132 CYS 132 114 114 CYS CYS B . n 
D 4 133 GLY 133 115 115 GLY GLY B . n 
D 4 134 GLY 134 116 116 GLY GLY B . n 
D 4 135 LEU 135 117 117 LEU LEU B . n 
D 4 136 ASP 136 118 118 ASP ASP B . n 
D 4 137 ASN 137 119 119 ASN ASN B . n 
D 4 138 ILE 138 120 120 ILE ILE B . n 
D 4 139 CYS 139 121 121 CYS CYS B . n 
D 4 140 SER 140 122 122 SER SER B . n 
D 4 141 ILE 141 123 123 ILE ILE B . n 
D 4 142 TYR 142 124 124 TYR TYR B . n 
D 4 143 ASN 143 125 125 ASN ASN B . n 
D 4 144 LEU 144 126 126 LEU LEU B . n 
D 4 145 LYS 145 127 127 LYS LYS B . n 
D 4 146 THR 146 128 128 THR THR B . n 
D 4 147 ARG 147 129 129 ARG ARG B . n 
D 4 148 GLU 148 130 130 GLU GLU B . n 
D 4 149 GLY 149 131 131 GLY GLY B . n 
D 4 150 ASN 150 132 132 ASN ASN B . n 
D 4 151 VAL 151 133 133 VAL VAL B . n 
D 4 152 ARG 152 134 134 ARG ARG B . n 
D 4 153 VAL 153 135 135 VAL VAL B . n 
D 4 154 SER 154 136 136 SER SER B . n 
D 4 155 ARG 155 137 137 ARG ARG B . n 
D 4 156 GLU 156 138 138 GLU GLU B . n 
D 4 157 LEU 157 139 139 LEU LEU B . n 
D 4 158 ALA 158 140 140 ALA ALA B . n 
D 4 159 GLY 159 141 141 GLY GLY B . n 
D 4 160 HIS 160 142 142 HIS HIS B . n 
D 4 161 THR 161 143 143 THR THR B . n 
D 4 162 GLY 162 144 144 GLY GLY B . n 
D 4 163 TYR 163 145 145 TYR TYR B . n 
D 4 164 LEU 164 146 146 LEU LEU B . n 
D 4 165 SER 165 147 147 SER SER B . n 
D 4 166 CYS 166 148 148 CYS CYS B . n 
D 4 167 CYS 167 149 149 CYS CYS B . n 
D 4 168 ARG 168 150 150 ARG ARG B . n 
D 4 169 PHE 169 151 151 PHE PHE B . n 
D 4 170 LEU 170 152 152 LEU LEU B . n 
D 4 171 ASP 171 153 153 ASP ASP B . n 
D 4 172 ASP 172 154 154 ASP ASP B . n 
D 4 173 ASN 173 155 155 ASN ASN B . n 
D 4 174 GLN 174 156 156 GLN GLN B . n 
D 4 175 ILE 175 157 157 ILE ILE B . n 
D 4 176 VAL 176 158 158 VAL VAL B . n 
D 4 177 THR 177 159 159 THR THR B . n 
D 4 178 SER 178 160 160 SER SER B . n 
D 4 179 SER 179 161 161 SER SER B . n 
D 4 180 GLY 180 162 162 GLY GLY B . n 
D 4 181 ASP 181 163 163 ASP ASP B . n 
D 4 182 THR 182 164 164 THR THR B . n 
D 4 183 THR 183 165 165 THR THR B . n 
D 4 184 CYS 184 166 166 CYS CYS B . n 
D 4 185 ALA 185 167 167 ALA ALA B . n 
D 4 186 LEU 186 168 168 LEU LEU B . n 
D 4 187 TRP 187 169 169 TRP TRP B . n 
D 4 188 ASP 188 170 170 ASP ASP B . n 
D 4 189 ILE 189 171 171 ILE ILE B . n 
D 4 190 GLU 190 172 172 GLU GLU B . n 
D 4 191 THR 191 173 173 THR THR B . n 
D 4 192 GLY 192 174 174 GLY GLY B . n 
D 4 193 GLN 193 175 175 GLN GLN B . n 
D 4 194 GLN 194 176 176 GLN GLN B . n 
D 4 195 THR 195 177 177 THR THR B . n 
D 4 196 THR 196 178 178 THR THR B . n 
D 4 197 THR 197 179 179 THR THR B . n 
D 4 198 PHE 198 180 180 PHE PHE B . n 
D 4 199 THR 199 181 181 THR THR B . n 
D 4 200 GLY 200 182 182 GLY GLY B . n 
D 4 201 HIS 201 183 183 HIS HIS B . n 
D 4 202 THR 202 184 184 THR THR B . n 
D 4 203 GLY 203 185 185 GLY GLY B . n 
D 4 204 ASP 204 186 186 ASP ASP B . n 
D 4 205 VAL 205 187 187 VAL VAL B . n 
D 4 206 MET 206 188 188 MET MET B . n 
D 4 207 SER 207 189 189 SER SER B . n 
D 4 208 LEU 208 190 190 LEU LEU B . n 
D 4 209 SER 209 191 191 SER SER B . n 
D 4 210 LEU 210 192 192 LEU LEU B . n 
D 4 211 ALA 211 193 193 ALA ALA B . n 
D 4 212 PRO 212 194 194 PRO PRO B . n 
D 4 213 ASP 213 195 195 ASP ASP B . n 
D 4 214 THR 214 196 196 THR THR B . n 
D 4 215 ARG 215 197 197 ARG ARG B . n 
D 4 216 LEU 216 198 198 LEU LEU B . n 
D 4 217 PHE 217 199 199 PHE PHE B . n 
D 4 218 VAL 218 200 200 VAL VAL B . n 
D 4 219 SER 219 201 201 SER SER B . n 
D 4 220 GLY 220 202 202 GLY GLY B . n 
D 4 221 ALA 221 203 203 ALA ALA B . n 
D 4 222 CYS 222 204 204 CYS CYS B . n 
D 4 223 ASP 223 205 205 ASP ASP B . n 
D 4 224 ALA 224 206 206 ALA ALA B . n 
D 4 225 SER 225 207 207 SER SER B . n 
D 4 226 ALA 226 208 208 ALA ALA B . n 
D 4 227 LYS 227 209 209 LYS LYS B . n 
D 4 228 LEU 228 210 210 LEU LEU B . n 
D 4 229 TRP 229 211 211 TRP TRP B . n 
D 4 230 ASP 230 212 212 ASP ASP B . n 
D 4 231 VAL 231 213 213 VAL VAL B . n 
D 4 232 ARG 232 214 214 ARG ARG B . n 
D 4 233 GLU 233 215 215 GLU GLU B . n 
D 4 234 GLY 234 216 216 GLY GLY B . n 
D 4 235 MET 235 217 217 MET MET B . n 
D 4 236 CYS 236 218 218 CYS CYS B . n 
D 4 237 ARG 237 219 219 ARG ARG B . n 
D 4 238 GLN 238 220 220 GLN GLN B . n 
D 4 239 THR 239 221 221 THR THR B . n 
D 4 240 PHE 240 222 222 PHE PHE B . n 
D 4 241 THR 241 223 223 THR THR B . n 
D 4 242 GLY 242 224 224 GLY GLY B . n 
D 4 243 HIS 243 225 225 HIS HIS B . n 
D 4 244 GLU 244 226 226 GLU GLU B . n 
D 4 245 SER 245 227 227 SER SER B . n 
D 4 246 ASP 246 228 228 ASP ASP B . n 
D 4 247 ILE 247 229 229 ILE ILE B . n 
D 4 248 ASN 248 230 230 ASN ASN B . n 
D 4 249 ALA 249 231 231 ALA ALA B . n 
D 4 250 ILE 250 232 232 ILE ILE B . n 
D 4 251 CYS 251 233 233 CYS CYS B . n 
D 4 252 PHE 252 234 234 PHE PHE B . n 
D 4 253 PHE 253 235 235 PHE PHE B . n 
D 4 254 PRO 254 236 236 PRO PRO B . n 
D 4 255 ASN 255 237 237 ASN ASN B . n 
D 4 256 GLY 256 238 238 GLY GLY B . n 
D 4 257 ASN 257 239 239 ASN ASN B . n 
D 4 258 ALA 258 240 240 ALA ALA B . n 
D 4 259 PHE 259 241 241 PHE PHE B . n 
D 4 260 ALA 260 242 242 ALA ALA B . n 
D 4 261 THR 261 243 243 THR THR B . n 
D 4 262 GLY 262 244 244 GLY GLY B . n 
D 4 263 SER 263 245 245 SER SER B . n 
D 4 264 ASP 264 246 246 ASP ASP B . n 
D 4 265 ASP 265 247 247 ASP ASP B . n 
D 4 266 ALA 266 248 248 ALA ALA B . n 
D 4 267 THR 267 249 249 THR THR B . n 
D 4 268 CYS 268 250 250 CYS CYS B . n 
D 4 269 ARG 269 251 251 ARG ARG B . n 
D 4 270 LEU 270 252 252 LEU LEU B . n 
D 4 271 PHE 271 253 253 PHE PHE B . n 
D 4 272 ASP 272 254 254 ASP ASP B . n 
D 4 273 LEU 273 255 255 LEU LEU B . n 
D 4 274 ARG 274 256 256 ARG ARG B . n 
D 4 275 ALA 275 257 257 ALA ALA B . n 
D 4 276 ASP 276 258 258 ASP ASP B . n 
D 4 277 GLN 277 259 259 GLN GLN B . n 
D 4 278 GLU 278 260 260 GLU GLU B . n 
D 4 279 LEU 279 261 261 LEU LEU B . n 
D 4 280 MET 280 262 262 MET MET B . n 
D 4 281 THR 281 263 263 THR THR B . n 
D 4 282 TYR 282 264 264 TYR TYR B . n 
D 4 283 SER 283 265 265 SER SER B . n 
D 4 284 HIS 284 266 266 HIS HIS B . n 
D 4 285 ASP 285 267 267 ASP ASP B . n 
D 4 286 ASN 286 268 268 ASN ASN B . n 
D 4 287 ILE 287 269 269 ILE ILE B . n 
D 4 288 ILE 288 270 270 ILE ILE B . n 
D 4 289 CYS 289 271 271 CYS CYS B . n 
D 4 290 GLY 290 272 272 GLY GLY B . n 
D 4 291 ILE 291 273 273 ILE ILE B . n 
D 4 292 THR 292 274 274 THR THR B . n 
D 4 293 SER 293 275 275 SER SER B . n 
D 4 294 VAL 294 276 276 VAL VAL B . n 
D 4 295 SER 295 277 277 SER SER B . n 
D 4 296 PHE 296 278 278 PHE PHE B . n 
D 4 297 SER 297 279 279 SER SER B . n 
D 4 298 LYS 298 280 280 LYS LYS B . n 
D 4 299 SER 299 281 281 SER SER B . n 
D 4 300 GLY 300 282 282 GLY GLY B . n 
D 4 301 ARG 301 283 283 ARG ARG B . n 
D 4 302 LEU 302 284 284 LEU LEU B . n 
D 4 303 LEU 303 285 285 LEU LEU B . n 
D 4 304 LEU 304 286 286 LEU LEU B . n 
D 4 305 ALA 305 287 287 ALA ALA B . n 
D 4 306 GLY 306 288 288 GLY GLY B . n 
D 4 307 TYR 307 289 289 TYR TYR B . n 
D 4 308 ASP 308 290 290 ASP ASP B . n 
D 4 309 ASP 309 291 291 ASP ASP B . n 
D 4 310 PHE 310 292 292 PHE PHE B . n 
D 4 311 ASN 311 293 293 ASN ASN B . n 
D 4 312 CYS 312 294 294 CYS CYS B . n 
D 4 313 ASN 313 295 295 ASN ASN B . n 
D 4 314 VAL 314 296 296 VAL VAL B . n 
D 4 315 TRP 315 297 297 TRP TRP B . n 
D 4 316 ASP 316 298 298 ASP ASP B . n 
D 4 317 ALA 317 299 299 ALA ALA B . n 
D 4 318 LEU 318 300 300 LEU LEU B . n 
D 4 319 LYS 319 301 301 LYS LYS B . n 
D 4 320 ALA 320 302 302 ALA ALA B . n 
D 4 321 ASP 321 303 303 ASP ASP B . n 
D 4 322 ARG 322 304 304 ARG ARG B . n 
D 4 323 ALA 323 305 305 ALA ALA B . n 
D 4 324 GLY 324 306 306 GLY GLY B . n 
D 4 325 VAL 325 307 307 VAL VAL B . n 
D 4 326 LEU 326 308 308 LEU LEU B . n 
D 4 327 ALA 327 309 309 ALA ALA B . n 
D 4 328 GLY 328 310 310 GLY GLY B . n 
D 4 329 HIS 329 311 311 HIS HIS B . n 
D 4 330 ASP 330 312 312 ASP ASP B . n 
D 4 331 ASN 331 313 313 ASN ASN B . n 
D 4 332 ARG 332 314 314 ARG ARG B . n 
D 4 333 VAL 333 315 315 VAL VAL B . n 
D 4 334 SER 334 316 316 SER SER B . n 
D 4 335 CYS 335 317 317 CYS CYS B . n 
D 4 336 LEU 336 318 318 LEU LEU B . n 
D 4 337 GLY 337 319 319 GLY GLY B . n 
D 4 338 VAL 338 320 320 VAL VAL B . n 
D 4 339 THR 339 321 321 THR THR B . n 
D 4 340 ASP 340 322 322 ASP ASP B . n 
D 4 341 ASP 341 323 323 ASP ASP B . n 
D 4 342 GLY 342 324 324 GLY GLY B . n 
D 4 343 MET 343 325 325 MET MET B . n 
D 4 344 ALA 344 326 326 ALA ALA B . n 
D 4 345 VAL 345 327 327 VAL VAL B . n 
D 4 346 ALA 346 328 328 ALA ALA B . n 
D 4 347 THR 347 329 329 THR THR B . n 
D 4 348 GLY 348 330 330 GLY GLY B . n 
D 4 349 SER 349 331 331 SER SER B . n 
D 4 350 TRP 350 332 332 TRP TRP B . n 
D 4 351 ASP 351 333 333 ASP ASP B . n 
D 4 352 SER 352 334 334 SER SER B . n 
D 4 353 PHE 353 335 335 PHE PHE B . n 
D 4 354 LEU 354 336 336 LEU LEU B . n 
D 4 355 LYS 355 337 337 LYS LYS B . n 
D 4 356 ILE 356 338 338 ILE ILE B . n 
D 4 357 TRP 357 339 339 TRP TRP B . n 
D 4 358 ASN 358 340 340 ASN ASN B . n 
E 5 1   MET 1   1   ?   ?   ?   C . n 
E 5 2   ALA 2   2   ?   ?   ?   C . n 
E 5 3   SER 3   3   ?   ?   ?   C . n 
E 5 4   ASN 4   4   ?   ?   ?   C . n 
E 5 5   ASN 5   5   ?   ?   ?   C . n 
E 5 6   THR 6   6   ?   ?   ?   C . n 
E 5 7   ALA 7   7   7   ALA ALA C . n 
E 5 8   SER 8   8   8   SER SER C . n 
E 5 9   ILE 9   9   9   ILE ILE C . n 
E 5 10  ALA 10  10  10  ALA ALA C . n 
E 5 11  GLN 11  11  11  GLN GLN C . n 
E 5 12  ALA 12  12  12  ALA ALA C . n 
E 5 13  ARG 13  13  13  ARG ARG C . n 
E 5 14  LYS 14  14  14  LYS LYS C . n 
E 5 15  LEU 15  15  15  LEU LEU C . n 
E 5 16  VAL 16  16  16  VAL VAL C . n 
E 5 17  GLU 17  17  17  GLU GLU C . n 
E 5 18  GLN 18  18  18  GLN GLN C . n 
E 5 19  LEU 19  19  19  LEU LEU C . n 
E 5 20  LYS 20  20  20  LYS LYS C . n 
E 5 21  MET 21  21  21  MET MET C . n 
E 5 22  GLU 22  22  22  GLU GLU C . n 
E 5 23  ALA 23  23  23  ALA ALA C . n 
E 5 24  ASN 24  24  24  ASN ASN C . n 
E 5 25  ILE 25  25  25  ILE ILE C . n 
E 5 26  ASP 26  26  26  ASP ASP C . n 
E 5 27  ARG 27  27  27  ARG ARG C . n 
E 5 28  ILE 28  28  28  ILE ILE C . n 
E 5 29  LYS 29  29  29  LYS LYS C . n 
E 5 30  VAL 30  30  30  VAL VAL C . n 
E 5 31  SER 31  31  31  SER SER C . n 
E 5 32  LYS 32  32  32  LYS LYS C . n 
E 5 33  ALA 33  33  33  ALA ALA C . n 
E 5 34  ALA 34  34  34  ALA ALA C . n 
E 5 35  ALA 35  35  35  ALA ALA C . n 
E 5 36  ASP 36  36  36  ASP ASP C . n 
E 5 37  LEU 37  37  37  LEU LEU C . n 
E 5 38  MET 38  38  38  MET MET C . n 
E 5 39  ALA 39  39  39  ALA ALA C . n 
E 5 40  TYR 40  40  40  TYR TYR C . n 
E 5 41  CYS 41  41  41  CYS CYS C . n 
E 5 42  GLU 42  42  42  GLU GLU C . n 
E 5 43  ALA 43  43  43  ALA ALA C . n 
E 5 44  HIS 44  44  44  HIS HIS C . n 
E 5 45  ALA 45  45  45  ALA ALA C . n 
E 5 46  LYS 46  46  46  LYS LYS C . n 
E 5 47  GLU 47  47  47  GLU GLU C . n 
E 5 48  ASP 48  48  48  ASP ASP C . n 
E 5 49  PRO 49  49  49  PRO PRO C . n 
E 5 50  LEU 50  50  50  LEU LEU C . n 
E 5 51  LEU 51  51  51  LEU LEU C . n 
E 5 52  THR 52  52  52  THR THR C . n 
E 5 53  PRO 53  53  53  PRO PRO C . n 
E 5 54  VAL 54  54  54  VAL VAL C . n 
E 5 55  PRO 55  55  55  PRO PRO C . n 
E 5 56  ALA 56  56  56  ALA ALA C . n 
E 5 57  SER 57  57  57  SER SER C . n 
E 5 58  GLU 58  58  58  GLU GLU C . n 
E 5 59  ASN 59  59  59  ASN ASN C . n 
E 5 60  PRO 60  60  60  PRO PRO C . n 
E 5 61  PHE 61  61  61  PHE PHE C . n 
E 5 62  ARG 62  62  62  ARG ARG C . n 
E 5 63  GLU 63  63  ?   ?   ?   C . n 
E 5 64  LYS 64  64  ?   ?   ?   C . n 
E 5 65  LYS 65  65  ?   ?   ?   C . n 
E 5 66  PHE 66  66  ?   ?   ?   C . n 
E 5 67  PHE 67  67  ?   ?   ?   C . n 
E 5 68  CYS 68  68  ?   ?   ?   C . n 
E 5 69  ALA 69  69  ?   ?   ?   C . n 
E 5 70  ILE 70  70  ?   ?   ?   C . n 
E 5 71  LEU 71  71  ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        XOT 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   XOT 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         F 
_pdbx_nonpoly_scheme.entity_id       6 
_pdbx_nonpoly_scheme.mon_id          XOT 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     401 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      XOT 
_pdbx_nonpoly_scheme.auth_mon_id     MKT 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 R LYS 28  ? CG  ? A LYS 33  CG  
2   1 Y 1 R LYS 28  ? CD  ? A LYS 33  CD  
3   1 Y 1 R LYS 28  ? CE  ? A LYS 33  CE  
4   1 Y 1 R LYS 28  ? NZ  ? A LYS 33  NZ  
5   1 Y 1 R LYS 57  ? CG  ? A LYS 62  CG  
6   1 Y 1 R LYS 57  ? CD  ? A LYS 62  CD  
7   1 Y 1 R LYS 57  ? CE  ? A LYS 62  CE  
8   1 Y 1 R LYS 57  ? NZ  ? A LYS 62  NZ  
9   1 Y 1 R LYS 165 ? CG  ? A LYS 170 CG  
10  1 Y 1 R LYS 165 ? CD  ? A LYS 170 CD  
11  1 Y 1 R LYS 165 ? CE  ? A LYS 170 CE  
12  1 Y 1 R LYS 165 ? NZ  ? A LYS 170 NZ  
13  1 Y 1 R GLN 217 ? CD  ? A GLN 222 CD  
14  1 Y 1 R GLN 217 ? OE1 ? A GLN 222 OE1 
15  1 Y 1 R GLN 217 ? NE2 ? A GLN 222 NE2 
16  1 Y 1 R LYS 227 ? CG  ? A LYS 232 CG  
17  1 Y 1 R LYS 227 ? CD  ? A LYS 232 CD  
18  1 Y 1 R LYS 227 ? CE  ? A LYS 232 CE  
19  1 Y 1 R LYS 227 ? NZ  ? A LYS 232 NZ  
20  1 Y 1 R PHE 296 ? CD1 ? A PHE 301 CD1 
21  1 Y 1 R PHE 296 ? CD2 ? A PHE 301 CD2 
22  1 Y 1 R PHE 296 ? CE1 ? A PHE 301 CE1 
23  1 Y 1 R PHE 296 ? CE2 ? A PHE 301 CE2 
24  1 Y 1 R PHE 296 ? CZ  ? A PHE 301 CZ  
25  1 Y 1 D LYS 19  ? CD  ? B LYS 19  CD  
26  1 Y 1 D LYS 19  ? CE  ? B LYS 19  CE  
27  1 Y 1 D LYS 19  ? NZ  ? B LYS 19  NZ  
28  1 Y 1 D LYS 43  ? CG  ? B LYS 43  CG  
29  1 Y 1 D LYS 43  ? CD  ? B LYS 43  CD  
30  1 Y 1 D LYS 43  ? CE  ? B LYS 43  CE  
31  1 Y 1 D LYS 43  ? NZ  ? B LYS 43  NZ  
32  1 Y 1 D ASP 62  ? CG  ? B ASP 62  CG  
33  1 Y 1 D ASP 62  ? OD1 ? B ASP 62  OD1 
34  1 Y 1 D ASP 62  ? OD2 ? B ASP 62  OD2 
35  1 Y 1 D LYS 65  ? CD  ? B LYS 65  CD  
36  1 Y 1 D LYS 65  ? CE  ? B LYS 65  CE  
37  1 Y 1 D LYS 65  ? NZ  ? B LYS 65  NZ  
38  1 Y 1 D ASP 73  ? CG  ? B ASP 73  CG  
39  1 Y 1 D ASP 73  ? OD1 ? B ASP 73  OD1 
40  1 Y 1 D ASP 73  ? OD2 ? B ASP 73  OD2 
41  1 Y 1 D ASP 125 ? OD1 ? B ASP 137 OD1 
42  1 Y 1 D ASP 125 ? OD2 ? B ASP 137 OD2 
43  1 Y 1 D GLU 141 ? CD  ? B GLU 153 CD  
44  1 Y 1 D GLU 141 ? OE1 ? B GLU 153 OE1 
45  1 Y 1 D GLU 141 ? OE2 ? B GLU 153 OE2 
46  1 Y 1 D ARG 206 ? CG  ? B ARG 218 CG  
47  1 Y 1 D ARG 206 ? CD  ? B ARG 218 CD  
48  1 Y 1 D ARG 206 ? NE  ? B ARG 218 NE  
49  1 Y 1 D ARG 206 ? CZ  ? B ARG 218 CZ  
50  1 Y 1 D ARG 206 ? NH1 ? B ARG 218 NH1 
51  1 Y 1 D ARG 206 ? NH2 ? B ARG 218 NH2 
52  1 Y 1 D GLU 208 ? CD  ? B GLU 220 CD  
53  1 Y 1 D GLU 208 ? OE1 ? B GLU 220 OE1 
54  1 Y 1 D GLU 208 ? OE2 ? B GLU 220 OE2 
55  1 Y 1 D GLU 210 ? CD  ? B GLU 222 CD  
56  1 Y 1 D GLU 210 ? OE1 ? B GLU 222 OE1 
57  1 Y 1 D GLU 210 ? OE2 ? B GLU 222 OE2 
58  1 Y 1 A ARG 24  ? NE  ? C ARG 24  NE  
59  1 Y 1 A ARG 24  ? CZ  ? C ARG 24  CZ  
60  1 Y 1 A ARG 24  ? NH1 ? C ARG 24  NH1 
61  1 Y 1 A ARG 24  ? NH2 ? C ARG 24  NH2 
62  1 Y 1 A GLU 28  ? CG  ? C GLU 28  CG  
63  1 Y 1 A GLU 28  ? CD  ? C GLU 28  CD  
64  1 Y 1 A GLU 28  ? OE1 ? C GLU 28  OE1 
65  1 Y 1 A GLU 28  ? OE2 ? C GLU 28  OE2 
66  1 Y 1 A GLU 33  ? CD  ? C GLU 33  CD  
67  1 Y 1 A GLU 33  ? OE1 ? C GLU 33  OE1 
68  1 Y 1 A GLU 33  ? OE2 ? C GLU 33  OE2 
69  1 Y 1 A GLU 43  ? CG  ? C GLU 43  CG  
70  1 Y 1 A GLU 43  ? CD  ? C GLU 43  CD  
71  1 Y 1 A GLU 43  ? OE1 ? C GLU 43  OE1 
72  1 Y 1 A GLU 43  ? OE2 ? C GLU 43  OE2 
73  1 Y 1 A GLU 186 ? CD  ? C GLU 186 CD  
74  1 Y 1 A GLU 186 ? OE1 ? C GLU 186 OE1 
75  1 Y 1 A GLU 186 ? OE2 ? C GLU 186 OE2 
76  1 Y 1 A LYS 197 ? CG  ? C LYS 197 CG  
77  1 Y 1 A LYS 197 ? CD  ? C LYS 197 CD  
78  1 Y 1 A LYS 197 ? CE  ? C LYS 197 CE  
79  1 Y 1 A LYS 197 ? NZ  ? C LYS 197 NZ  
80  1 Y 1 A ARG 205 ? CD  ? C ARG 205 CD  
81  1 Y 1 A ARG 205 ? NE  ? C ARG 205 NE  
82  1 Y 1 A ARG 205 ? CZ  ? C ARG 205 CZ  
83  1 Y 1 A ARG 205 ? NH1 ? C ARG 205 NH1 
84  1 Y 1 A ARG 205 ? NH2 ? C ARG 205 NH2 
85  1 Y 1 A GLU 236 ? CD  ? C GLU 236 CD  
86  1 Y 1 A GLU 236 ? OE1 ? C GLU 236 OE1 
87  1 Y 1 A GLU 236 ? OE2 ? C GLU 236 OE2 
88  1 Y 1 A GLU 238 ? CD  ? C GLU 238 CD  
89  1 Y 1 A GLU 238 ? OE1 ? C GLU 238 OE1 
90  1 Y 1 A GLU 238 ? OE2 ? C GLU 238 OE2 
91  1 Y 1 A MET 240 ? SD  ? C MET 240 SD  
92  1 Y 1 A MET 240 ? CE  ? C MET 240 CE  
93  1 Y 1 A LYS 248 ? CD  ? C LYS 248 CD  
94  1 Y 1 A LYS 248 ? CE  ? C LYS 248 CE  
95  1 Y 1 A LYS 248 ? NZ  ? C LYS 248 NZ  
96  1 Y 1 B LEU 7   ? CG  ? D LEU 25  CG  
97  1 Y 1 B LEU 7   ? CD1 ? D LEU 25  CD1 
98  1 Y 1 B LEU 7   ? CD2 ? D LEU 25  CD2 
99  1 Y 1 B ARG 8   ? CD  ? D ARG 26  CD  
100 1 Y 1 B ARG 8   ? NE  ? D ARG 26  NE  
101 1 Y 1 B ARG 8   ? CZ  ? D ARG 26  CZ  
102 1 Y 1 B ARG 8   ? NH1 ? D ARG 26  NH1 
103 1 Y 1 B ARG 8   ? NH2 ? D ARG 26  NH2 
104 1 Y 1 B GLN 9   ? CD  ? D GLN 27  CD  
105 1 Y 1 B GLN 9   ? OE1 ? D GLN 27  OE1 
106 1 Y 1 B GLN 9   ? NE2 ? D GLN 27  NE2 
107 1 Y 1 B LYS 15  ? CD  ? D LYS 33  CD  
108 1 Y 1 B LYS 15  ? CE  ? D LYS 33  CE  
109 1 Y 1 B LYS 15  ? NZ  ? D LYS 33  NZ  
110 1 Y 1 B LYS 23  ? CD  ? D LYS 41  CD  
111 1 Y 1 B LYS 23  ? CE  ? D LYS 41  CE  
112 1 Y 1 B LYS 23  ? NZ  ? D LYS 41  NZ  
113 1 Y 1 B ASP 118 ? CG  ? D ASP 136 CG  
114 1 Y 1 B ASP 118 ? OD1 ? D ASP 136 OD1 
115 1 Y 1 B ASP 118 ? OD2 ? D ASP 136 OD2 
116 1 Y 1 B ASP 312 ? CG  ? D ASP 330 CG  
117 1 Y 1 B ASP 312 ? OD1 ? D ASP 330 OD1 
118 1 Y 1 B ASP 312 ? OD2 ? D ASP 330 OD2 
119 1 Y 1 C LYS 14  ? CD  ? E LYS 14  CD  
120 1 Y 1 C LYS 14  ? CE  ? E LYS 14  CE  
121 1 Y 1 C LYS 14  ? NZ  ? E LYS 14  NZ  
122 1 Y 1 C GLU 22  ? CD  ? E GLU 22  CD  
123 1 Y 1 C GLU 22  ? OE1 ? E GLU 22  OE1 
124 1 Y 1 C GLU 22  ? OE2 ? E GLU 22  OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UTD 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UTD 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UTD 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8UTD 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 9166 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? ?     ? ?    ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.285 ? 1236 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.043 ? 1393 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 1568 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8UTD 
_struct.title                        'CryoEM Structure of HCA2-Gi1 in complex with MK-1903' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UTD 
_struct_keywords.text            'GPCR, HCA2, MK 1903, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP HCAR2_HUMAN Q8TDS4 ? 1 
;MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWKSSRIFLFNLAVADFLLIICL
PFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTVVAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTV
HLLKKKMPIQNGGANLCSSFSICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPSFPNFFSTLINRCLQRKMTGE
PDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGPTSP
;
1 
2 PDB 8UTD        8UTD   ? 2 ? 1 
3 UNP GNAI1_HUMAN P63096 ? 3 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1 
4 UNP GBB1_HUMAN  P62873 ? 4 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2 
5 UNP GBG2_HUMAN  P59768 ? 5 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UTD R 6  ? 368 ? Q8TDS4 1 ? 363 ? 1 363 
2 2 8UTD D 1  ? 267 ? 8UTD   1 ? 255 ? 1 255 
3 3 8UTD A 1  ? 354 ? P63096 1 ? 354 ? 1 354 
4 4 8UTD B 20 ? 358 ? P62873 2 ? 340 ? 2 340 
5 5 8UTD C 1  ? 71  ? P59768 1 ? 71  ? 1 71  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UTD GLN R 1   ? UNP Q8TDS4 ?   ?   'expression tag'      -4  1  
1 8UTD GLY R 2   ? UNP Q8TDS4 ?   ?   'expression tag'      -3  2  
1 8UTD GLY R 3   ? UNP Q8TDS4 ?   ?   'expression tag'      -2  3  
1 8UTD THR R 4   ? UNP Q8TDS4 ?   ?   'expression tag'      -1  4  
1 8UTD THR R 5   ? UNP Q8TDS4 ?   ?   'expression tag'      0   5  
1 8UTD ALA R 129 ? UNP Q8TDS4 ASP 124 'engineered mutation' 124 6  
3 8UTD ALA A 203 ? UNP P63096 GLY 203 'engineered mutation' 203 7  
3 8UTD SER A 326 ? UNP P63096 ALA 326 'engineered mutation' 326 8  
4 8UTD MET B 1   ? UNP P62873 ?   ?   'expression tag'      -17 9  
4 8UTD HIS B 2   ? UNP P62873 ?   ?   'expression tag'      -16 10 
4 8UTD HIS B 3   ? UNP P62873 ?   ?   'expression tag'      -15 11 
4 8UTD HIS B 4   ? UNP P62873 ?   ?   'expression tag'      -14 12 
4 8UTD HIS B 5   ? UNP P62873 ?   ?   'expression tag'      -13 13 
4 8UTD HIS B 6   ? UNP P62873 ?   ?   'expression tag'      -12 14 
4 8UTD HIS B 7   ? UNP P62873 ?   ?   'expression tag'      -11 15 
4 8UTD LEU B 8   ? UNP P62873 ?   ?   'expression tag'      -10 16 
4 8UTD GLU B 9   ? UNP P62873 ?   ?   'expression tag'      -9  17 
4 8UTD VAL B 10  ? UNP P62873 ?   ?   'expression tag'      -8  18 
4 8UTD LEU B 11  ? UNP P62873 ?   ?   'expression tag'      -7  19 
4 8UTD PHE B 12  ? UNP P62873 ?   ?   'expression tag'      -6  20 
4 8UTD GLN B 13  ? UNP P62873 ?   ?   'expression tag'      -5  21 
4 8UTD GLY B 14  ? UNP P62873 ?   ?   'expression tag'      -4  22 
4 8UTD PRO B 15  ? UNP P62873 ?   ?   'expression tag'      -3  23 
4 8UTD GLY B 16  ? UNP P62873 ?   ?   'expression tag'      -2  24 
4 8UTD SER B 17  ? UNP P62873 ?   ?   'expression tag'      -1  25 
4 8UTD SER B 18  ? UNP P62873 ?   ?   'expression tag'      0   26 
4 8UTD GLY B 19  ? UNP P62873 ?   ?   'expression tag'      1   27 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 28  ? HIS A 60  ? ASP R 23  HIS R 55  1 ? 33 
HELX_P HELX_P2  AA2 LYS A 65  ? ARG A 94  ? LYS R 60  ARG R 89  1 ? 30 
HELX_P HELX_P3  AA3 GLY A 101 ? VAL A 135 ? GLY R 96  VAL R 130 1 ? 35 
HELX_P HELX_P4  AA4 HIS A 139 ? ILE A 144 ? HIS R 134 ILE R 139 5 ? 6  
HELX_P HELX_P5  AA5 SER A 145 ? VAL A 165 ? SER R 140 VAL R 160 1 ? 21 
HELX_P HELX_P6  AA6 HIS A 166 ? LYS A 170 ? HIS R 161 LYS R 165 5 ? 5  
HELX_P HELX_P7  AA7 GLN A 192 ? GLN A 222 ? GLN R 187 GLN R 217 1 ? 31 
HELX_P HELX_P8  AA8 HIS A 228 ? SER A 266 ? HIS R 223 SER R 261 1 ? 39 
HELX_P HELX_P9  AA9 ASN A 270 ? VAL A 273 ? ASN R 265 VAL R 268 5 ? 4  
HELX_P HELX_P10 AB1 TYR A 274 ? TYR A 300 ? TYR R 269 TYR R 295 1 ? 27 
HELX_P HELX_P11 AB2 ALA B 28  ? PHE B 32  ? ALA D 28  PHE D 32  5 ? 5  
HELX_P HELX_P12 AB3 ARG B 87  ? THR B 91  ? ARG D 87  THR D 91  5 ? 5  
HELX_P HELX_P13 AB4 SER C 6   ? ARG C 32  ? SER A 6   ARG A 32  1 ? 27 
HELX_P HELX_P14 AB5 GLY C 45  ? GLN C 52  ? GLY A 45  GLN A 52  1 ? 8  
HELX_P HELX_P15 AB6 GLU C 207 ? GLU C 216 ? GLU A 207 GLU A 216 5 ? 10 
HELX_P HELX_P16 AB7 ALA C 226 ? TYR C 230 ? ALA A 226 TYR A 230 5 ? 5  
HELX_P HELX_P17 AB8 ASN C 241 ? ASN C 255 ? ASN A 241 ASN A 255 1 ? 15 
HELX_P HELX_P18 AB9 LYS C 271 ? SER C 281 ? LYS A 271 SER A 281 1 ? 11 
HELX_P HELX_P19 AC1 THR C 295 ? ASP C 309 ? THR A 295 ASP A 309 1 ? 15 
HELX_P HELX_P20 AC2 LYS C 330 ? CYS C 351 ? LYS A 330 CYS A 351 1 ? 22 
HELX_P HELX_P21 AC3 LEU D 22  ? ALA D 44  ? LEU B 4   ALA B 26  1 ? 23 
HELX_P HELX_P22 AC4 THR D 47  ? THR D 52  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P23 AC5 LYS D 298 ? GLY D 300 ? LYS B 280 GLY B 282 5 ? 3  
HELX_P HELX_P24 AC6 SER E 8   ? ASN E 24  ? SER C 8   ASN C 24  1 ? 17 
HELX_P HELX_P25 AC7 LYS E 29  ? HIS E 44  ? LYS C 29  HIS C 44  1 ? 16 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 23  SG ? ? ? 1_555 A CYS 188 SG ? ? R CYS 18  R CYS 183 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf2 disulf ? ? A CYS 24  SG ? ? ? 1_555 A CYS 271 SG ? ? R CYS 19  R CYS 266 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? A CYS 105 SG ? ? ? 1_555 A CYS 182 SG ? ? R CYS 100 R CYS 177 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf4 disulf ? ? B CYS 159 SG ? ? ? 1_555 B CYS 229 SG ? ? D CYS 147 D CYS 217 1_555 ? ? ? ? ? ? ? 2.041 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 23  ? CYS A 188 ? CYS R 18  ? 1_555 CYS R 183 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 24  ? CYS A 271 ? CYS R 19  ? 1_555 CYS R 266 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 105 ? CYS A 182 ? CYS R 100 ? 1_555 CYS R 177 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS B 159 ? CYS B 229 ? CYS D 147 ? 1_555 CYS D 217 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          B 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            223 
_struct_mon_prot_cis.auth_asym_id           D 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   B 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     224 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    D 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       9.15 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 4 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 6 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? parallel      
AA6 4 5 ? parallel      
AA6 5 6 ? parallel      
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 174 ? ASN A 176 ? ILE R 169 ASN R 171 
AA1 2 ALA A 179 ? LEU A 181 ? ALA R 174 LEU R 176 
AA2 1 GLN B 3   ? SER B 7   ? GLN D 3   SER D 7   
AA2 2 ARG B 18  ? SER B 25  ? ARG D 18  SER D 25  
AA2 3 THR B 78  ? MET B 83  ? THR D 78  MET D 83  
AA2 4 THR B 69  ? ASP B 73  ? THR D 69  ASP D 73  
AA3 1 GLY B 10  ? LEU B 11  ? GLY D 10  LEU D 11  
AA3 2 THR B 115 ? THR B 118 ? THR D 115 THR D 118 
AA3 3 ALA B 92  ? SER B 99  ? ALA D 92  SER D 99  
AA3 4 GLY B 33  ? GLN B 39  ? GLY D 33  GLN D 39  
AA3 5 LEU B 45  ? ILE B 51  ? LEU D 45  ILE D 51  
AA3 6 ILE B 58  ? TYR B 60  ? ILE D 58  TYR D 60  
AA4 1 MET B 140 ? GLN B 142 ? MET D 128 GLN D 130 
AA4 2 SER B 154 ? SER B 161 ? SER D 142 SER D 149 
AA4 3 ALA B 211 ? SER B 217 ? ALA D 199 SER D 205 
AA4 4 PHE B 203 ? SER B 208 ? PHE D 191 SER D 196 
AA5 1 VAL B 147 ? PRO B 148 ? VAL D 135 PRO D 136 
AA5 2 THR B 243 ? GLU B 246 ? THR D 231 GLU D 234 
AA5 3 GLY B 225 ? GLN B 231 ? GLY D 213 GLN D 219 
AA5 4 LEU B 174 ? GLN B 179 ? LEU D 162 GLN D 167 
AA5 5 GLN B 186 ? TYR B 190 ? GLN D 174 TYR D 178 
AA5 6 ASN B 194 ? LEU B 195 ? ASN D 182 LEU D 183 
AA6 1 VAL C 185 ? THR C 187 ? VAL A 185 THR A 187 
AA6 2 PHE C 196 ? ASP C 200 ? PHE A 196 ASP A 200 
AA6 3 VAL C 34  ? GLY C 40  ? VAL A 34  GLY A 40  
AA6 4 ALA C 220 ? VAL C 225 ? ALA A 220 VAL A 225 
AA6 5 PHE C 267 ? LEU C 268 ? PHE A 267 LEU A 268 
AA6 6 HIS C 322 ? PHE C 323 ? HIS A 322 PHE A 323 
AA7 1 ARG D 64  ? LEU D 69  ? ARG B 46  LEU B 51  
AA7 2 LEU D 354 ? ASN D 358 ? LEU B 336 ASN B 340 
AA7 3 VAL D 345 ? SER D 349 ? VAL B 327 SER B 331 
AA7 4 VAL D 333 ? VAL D 338 ? VAL B 315 VAL B 320 
AA8 1 ALA D 78  ? TRP D 81  ? ALA B 60  TRP B 63  
AA8 2 LEU D 87  ? ALA D 91  ? LEU B 69  ALA B 73  
AA8 3 LEU D 97  ? ASP D 101 ? LEU B 79  ASP B 83  
AA8 4 LYS D 107 ? ILE D 111 ? LYS B 89  ILE B 93  
AA9 1 THR D 120 ? TYR D 123 ? THR B 102 TYR B 105 
AA9 2 TYR D 129 ? GLY D 133 ? TYR B 111 GLY B 115 
AA9 3 CYS D 139 ? ASN D 143 ? CYS B 121 ASN B 125 
AA9 4 ARG D 152 ? LEU D 157 ? ARG B 134 LEU B 139 
AB1 1 LEU D 164 ? PHE D 169 ? LEU B 146 PHE B 151 
AB1 2 ILE D 175 ? SER D 179 ? ILE B 157 SER B 161 
AB1 3 CYS D 184 ? LEU D 186 ? CYS B 166 LEU B 168 
AB1 4 THR D 196 ? PHE D 198 ? THR B 178 PHE B 180 
AB2 1 VAL D 205 ? LEU D 210 ? VAL B 187 LEU B 192 
AB2 2 LEU D 216 ? ALA D 221 ? LEU B 198 ALA B 203 
AB2 3 SER D 225 ? ASP D 230 ? SER B 207 ASP B 212 
AB2 4 CYS D 236 ? THR D 241 ? CYS B 218 THR B 223 
AB3 1 ILE D 247 ? PHE D 252 ? ILE B 229 PHE B 234 
AB3 2 ALA D 258 ? SER D 263 ? ALA B 240 SER B 245 
AB3 3 CYS D 268 ? ASP D 272 ? CYS B 250 ASP B 254 
AB3 4 GLN D 277 ? TYR D 282 ? GLN B 259 TYR B 264 
AB4 1 ILE D 291 ? PHE D 296 ? ILE B 273 PHE B 278 
AB4 2 LEU D 302 ? TYR D 307 ? LEU B 284 TYR B 289 
AB4 3 CYS D 312 ? ASP D 316 ? CYS B 294 ASP B 298 
AB4 4 ARG D 322 ? VAL D 325 ? ARG B 304 VAL B 307 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 174 ? N ILE R 169 O LEU A 181 ? O LEU R 176 
AA2 1 2 N SER B 7   ? N SER D 7   O SER B 21  ? O SER D 21  
AA2 2 3 N ARG B 18  ? N ARG D 18  O MET B 83  ? O MET D 83  
AA2 3 4 O THR B 78  ? O THR D 78  N ASP B 73  ? N ASP D 73  
AA3 1 2 N GLY B 10  ? N GLY D 10  O THR B 118 ? O THR D 118 
AA3 2 3 O THR B 115 ? O THR D 115 N TYR B 94  ? N TYR D 94  
AA3 3 4 O MET B 93  ? O MET D 93  N GLN B 39  ? N GLN D 39  
AA3 4 5 N ARG B 38  ? N ARG D 38  O GLU B 46  ? O GLU D 46  
AA3 5 6 N TYR B 50  ? N TYR D 50  O TYR B 59  ? O TYR D 59  
AA4 1 2 N THR B 141 ? N THR D 129 O ARG B 160 ? O ARG D 148 
AA4 2 3 N VAL B 155 ? N VAL D 143 O ILE B 216 ? O ILE D 204 
AA4 3 4 O THR B 213 ? O THR D 201 N SER B 206 ? N SER D 194 
AA5 1 2 N VAL B 147 ? N VAL D 135 O GLU B 246 ? O GLU D 234 
AA5 2 3 O THR B 243 ? O THR D 231 N TYR B 227 ? N TYR D 215 
AA5 3 4 O VAL B 226 ? O VAL D 214 N GLN B 179 ? N GLN D 167 
AA5 4 5 N TRP B 176 ? N TRP D 164 O ILE B 189 ? O ILE D 177 
AA5 5 6 N TYR B 190 ? N TYR D 178 O ASN B 194 ? O ASN D 182 
AA6 1 2 N THR C 187 ? N THR A 187 O MET C 198 ? O MET A 198 
AA6 2 3 O PHE C 199 ? O PHE A 199 N LEU C 38  ? N LEU A 38  
AA6 3 4 N LEU C 37  ? N LEU A 37  O ILE C 222 ? O ILE A 222 
AA6 4 5 N PHE C 223 ? N PHE A 223 O PHE C 267 ? O PHE A 267 
AA6 5 6 N LEU C 268 ? N LEU A 268 O HIS C 322 ? O HIS A 322 
AA7 1 2 N ARG D 64  ? N ARG B 46  O ASN D 358 ? O ASN B 340 
AA7 2 3 O TRP D 357 ? O TRP B 339 N VAL D 345 ? N VAL B 327 
AA7 3 4 O GLY D 348 ? O GLY B 330 N CYS D 335 ? N CYS B 317 
AA8 1 2 N ALA D 78  ? N ALA B 60  O ALA D 91  ? O ALA B 73  
AA8 2 3 N LEU D 88  ? N LEU B 70  O TRP D 100 ? O TRP B 82  
AA8 3 4 N LEU D 97  ? N LEU B 79  O ILE D 111 ? O ILE B 93  
AA9 1 2 N ALA D 122 ? N ALA B 104 O ALA D 131 ? O ALA B 113 
AA9 2 3 N VAL D 130 ? N VAL B 112 O TYR D 142 ? O TYR B 124 
AA9 3 4 N ILE D 141 ? N ILE B 123 O ARG D 155 ? O ARG B 137 
AB1 1 2 N SER D 165 ? N SER B 147 O SER D 178 ? O SER B 160 
AB1 2 3 N THR D 177 ? N THR B 159 O ALA D 185 ? O ALA B 167 
AB1 3 4 N CYS D 184 ? N CYS B 166 O PHE D 198 ? O PHE B 180 
AB2 1 2 N SER D 207 ? N SER B 189 O GLY D 220 ? O GLY B 202 
AB2 2 3 N PHE D 217 ? N PHE B 199 O TRP D 229 ? O TRP B 211 
AB2 3 4 N LEU D 228 ? N LEU B 210 O ARG D 237 ? O ARG B 219 
AB3 1 2 N ALA D 249 ? N ALA B 231 O GLY D 262 ? O GLY B 244 
AB3 2 3 N PHE D 259 ? N PHE B 241 O PHE D 271 ? O PHE B 253 
AB3 3 4 N LEU D 270 ? N LEU B 252 O LEU D 279 ? O LEU B 261 
AB4 1 2 N SER D 293 ? N SER B 275 O GLY D 306 ? O GLY B 288 
AB4 2 3 N LEU D 303 ? N LEU B 285 O TRP D 315 ? O TRP B 297 
AB4 3 4 N VAL D 314 ? N VAL B 296 O ALA D 323 ? O ALA B 305 
# 
_pdbx_entry_details.entry_id                   8UTD 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN R 219 ? ? 62.29   61.27   
2  1 THR R 260 ? ? -95.39  -61.76  
3  1 VAL D 48  ? ? -120.75 -56.29  
4  1 MET D 180 ? ? 72.38   -11.23  
5  1 HIS D 220 ? ? -142.49 28.36   
6  1 ARG A 32  ? ? -91.19  53.68   
7  1 ASP A 231 ? ? 55.87   -148.09 
8  1 LEU A 266 ? ? -38.45  123.92  
9  1 TYR A 287 ? ? 52.58   76.02   
10 1 ASN A 294 ? ? -107.85 40.73   
11 1 SER B 74  ? ? -111.44 -166.76 
12 1 GLN B 75  ? ? -99.30  51.34   
13 1 THR B 87  ? ? 73.34   -10.47  
14 1 ASN B 119 ? ? 79.24   -4.56   
15 1 SER B 281 ? ? 70.41   -4.03   
16 1 ASP B 291 ? ? -92.62  49.43   
17 1 ASN C 24  ? ? -99.67  36.71   
18 1 ALA C 56  ? ? -68.17  0.15    
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG R 63  ? ? 0.101 'SIDE CHAIN' 
2 1 ARG B 304 ? ? 0.289 'SIDE CHAIN' 
3 1 ARG B 314 ? ? 0.289 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8UTD 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_reconstruction.entry_id                    8UTD 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.24 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               283876 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Human HCA2-Gai1 in complex with MK1903' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8UTD 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             1900 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8UTD 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE-PROPANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UTD 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 R GLN -4  ? A GLN 1   
2   1 Y 1 R GLY -3  ? A GLY 2   
3   1 Y 1 R GLY -2  ? A GLY 3   
4   1 Y 1 R THR -1  ? A THR 4   
5   1 Y 1 R THR 0   ? A THR 5   
6   1 Y 1 R MET 1   ? A MET 6   
7   1 Y 1 R ASN 2   ? A ASN 7   
8   1 Y 1 R ARG 3   ? A ARG 8   
9   1 Y 1 R HIS 4   ? A HIS 9   
10  1 Y 1 R HIS 5   ? A HIS 10  
11  1 Y 1 R LEU 6   ? A LEU 11  
12  1 Y 1 R PRO 299 ? A PRO 304 
13  1 Y 1 R SER 300 ? A SER 305 
14  1 Y 1 R PHE 301 ? A PHE 306 
15  1 Y 1 R PRO 302 ? A PRO 307 
16  1 Y 1 R ASN 303 ? A ASN 308 
17  1 Y 1 R PHE 304 ? A PHE 309 
18  1 Y 1 R PHE 305 ? A PHE 310 
19  1 Y 1 R SER 306 ? A SER 311 
20  1 Y 1 R THR 307 ? A THR 312 
21  1 Y 1 R LEU 308 ? A LEU 313 
22  1 Y 1 R ILE 309 ? A ILE 314 
23  1 Y 1 R ASN 310 ? A ASN 315 
24  1 Y 1 R ARG 311 ? A ARG 316 
25  1 Y 1 R CYS 312 ? A CYS 317 
26  1 Y 1 R LEU 313 ? A LEU 318 
27  1 Y 1 R GLN 314 ? A GLN 319 
28  1 Y 1 R ARG 315 ? A ARG 320 
29  1 Y 1 R LYS 316 ? A LYS 321 
30  1 Y 1 R MET 317 ? A MET 322 
31  1 Y 1 R THR 318 ? A THR 323 
32  1 Y 1 R GLY 319 ? A GLY 324 
33  1 Y 1 R GLU 320 ? A GLU 325 
34  1 Y 1 R PRO 321 ? A PRO 326 
35  1 Y 1 R ASP 322 ? A ASP 327 
36  1 Y 1 R ASN 323 ? A ASN 328 
37  1 Y 1 R ASN 324 ? A ASN 329 
38  1 Y 1 R ARG 325 ? A ARG 330 
39  1 Y 1 R SER 326 ? A SER 331 
40  1 Y 1 R THR 327 ? A THR 332 
41  1 Y 1 R SER 328 ? A SER 333 
42  1 Y 1 R VAL 329 ? A VAL 334 
43  1 Y 1 R GLU 330 ? A GLU 335 
44  1 Y 1 R LEU 331 ? A LEU 336 
45  1 Y 1 R THR 332 ? A THR 337 
46  1 Y 1 R GLY 333 ? A GLY 338 
47  1 Y 1 R ASP 334 ? A ASP 339 
48  1 Y 1 R PRO 335 ? A PRO 340 
49  1 Y 1 R ASN 336 ? A ASN 341 
50  1 Y 1 R LYS 337 ? A LYS 342 
51  1 Y 1 R THR 338 ? A THR 343 
52  1 Y 1 R ARG 339 ? A ARG 344 
53  1 Y 1 R GLY 340 ? A GLY 345 
54  1 Y 1 R ALA 341 ? A ALA 346 
55  1 Y 1 R PRO 342 ? A PRO 347 
56  1 Y 1 R GLU 343 ? A GLU 348 
57  1 Y 1 R ALA 344 ? A ALA 349 
58  1 Y 1 R LEU 345 ? A LEU 350 
59  1 Y 1 R MET 346 ? A MET 351 
60  1 Y 1 R ALA 347 ? A ALA 352 
61  1 Y 1 R ASN 348 ? A ASN 353 
62  1 Y 1 R SER 349 ? A SER 354 
63  1 Y 1 R GLY 350 ? A GLY 355 
64  1 Y 1 R GLU 351 ? A GLU 356 
65  1 Y 1 R PRO 352 ? A PRO 357 
66  1 Y 1 R TRP 353 ? A TRP 358 
67  1 Y 1 R SER 354 ? A SER 359 
68  1 Y 1 R PRO 355 ? A PRO 360 
69  1 Y 1 R SER 356 ? A SER 361 
70  1 Y 1 R TYR 357 ? A TYR 362 
71  1 Y 1 R LEU 358 ? A LEU 363 
72  1 Y 1 R GLY 359 ? A GLY 364 
73  1 Y 1 R PRO 360 ? A PRO 365 
74  1 Y 1 R THR 361 ? A THR 366 
75  1 Y 1 R SER 362 ? A SER 367 
76  1 Y 1 R PRO 363 ? A PRO 368 
77  1 Y 1 D ASP 1   ? B ASP 1   
78  1 Y 1 D SER 120 A B SER 121 
79  1 Y 1 D GLY 120 B B GLY 122 
80  1 Y 1 D GLY 120 C B GLY 123 
81  1 Y 1 D GLY 120 D B GLY 124 
82  1 Y 1 D GLY 120 E B GLY 125 
83  1 Y 1 D SER 120 F B SER 126 
84  1 Y 1 D GLY 120 G B GLY 127 
85  1 Y 1 D GLY 120 H B GLY 128 
86  1 Y 1 D GLY 120 I B GLY 129 
87  1 Y 1 D GLY 120 J B GLY 130 
88  1 Y 1 D SER 120 K B SER 131 
89  1 Y 1 D GLY 120 L B GLY 132 
90  1 Y 1 D GLY 120 M B GLY 133 
91  1 Y 1 D GLY 120 N B GLY 134 
92  1 Y 1 D GLY 120 O B GLY 135 
93  1 Y 1 D LYS 236 ? B LYS 248 
94  1 Y 1 D ALA 237 ? B ALA 249 
95  1 Y 1 D ALA 238 ? B ALA 250 
96  1 Y 1 D ALA 239 ? B ALA 251 
97  1 Y 1 D LEU 240 ? B LEU 252 
98  1 Y 1 D GLU 241 ? B GLU 253 
99  1 Y 1 D VAL 242 ? B VAL 254 
100 1 Y 1 D LEU 243 ? B LEU 255 
101 1 Y 1 D PHE 244 ? B PHE 256 
102 1 Y 1 D GLN 245 ? B GLN 257 
103 1 Y 1 D GLY 246 ? B GLY 258 
104 1 Y 1 D PRO 247 ? B PRO 259 
105 1 Y 1 D HIS 248 ? B HIS 260 
106 1 Y 1 D HIS 249 ? B HIS 261 
107 1 Y 1 D HIS 250 ? B HIS 262 
108 1 Y 1 D HIS 251 ? B HIS 263 
109 1 Y 1 D HIS 252 ? B HIS 264 
110 1 Y 1 D HIS 253 ? B HIS 265 
111 1 Y 1 D HIS 254 ? B HIS 266 
112 1 Y 1 D HIS 255 ? B HIS 267 
113 1 Y 1 A MET 1   ? C MET 1   
114 1 Y 1 A GLY 2   ? C GLY 2   
115 1 Y 1 A CYS 3   ? C CYS 3   
116 1 Y 1 A THR 4   ? C THR 4   
117 1 Y 1 A MET 53  ? C MET 53  
118 1 Y 1 A LYS 54  ? C LYS 54  
119 1 Y 1 A ILE 55  ? C ILE 55  
120 1 Y 1 A ILE 56  ? C ILE 56  
121 1 Y 1 A HIS 57  ? C HIS 57  
122 1 Y 1 A GLU 58  ? C GLU 58  
123 1 Y 1 A ALA 59  ? C ALA 59  
124 1 Y 1 A GLY 60  ? C GLY 60  
125 1 Y 1 A TYR 61  ? C TYR 61  
126 1 Y 1 A SER 62  ? C SER 62  
127 1 Y 1 A GLU 63  ? C GLU 63  
128 1 Y 1 A GLU 64  ? C GLU 64  
129 1 Y 1 A GLU 65  ? C GLU 65  
130 1 Y 1 A CYS 66  ? C CYS 66  
131 1 Y 1 A LYS 67  ? C LYS 67  
132 1 Y 1 A GLN 68  ? C GLN 68  
133 1 Y 1 A TYR 69  ? C TYR 69  
134 1 Y 1 A LYS 70  ? C LYS 70  
135 1 Y 1 A ALA 71  ? C ALA 71  
136 1 Y 1 A VAL 72  ? C VAL 72  
137 1 Y 1 A VAL 73  ? C VAL 73  
138 1 Y 1 A TYR 74  ? C TYR 74  
139 1 Y 1 A SER 75  ? C SER 75  
140 1 Y 1 A ASN 76  ? C ASN 76  
141 1 Y 1 A THR 77  ? C THR 77  
142 1 Y 1 A ILE 78  ? C ILE 78  
143 1 Y 1 A GLN 79  ? C GLN 79  
144 1 Y 1 A SER 80  ? C SER 80  
145 1 Y 1 A ILE 81  ? C ILE 81  
146 1 Y 1 A ILE 82  ? C ILE 82  
147 1 Y 1 A ALA 83  ? C ALA 83  
148 1 Y 1 A ILE 84  ? C ILE 84  
149 1 Y 1 A ILE 85  ? C ILE 85  
150 1 Y 1 A ARG 86  ? C ARG 86  
151 1 Y 1 A ALA 87  ? C ALA 87  
152 1 Y 1 A MET 88  ? C MET 88  
153 1 Y 1 A GLY 89  ? C GLY 89  
154 1 Y 1 A ARG 90  ? C ARG 90  
155 1 Y 1 A LEU 91  ? C LEU 91  
156 1 Y 1 A LYS 92  ? C LYS 92  
157 1 Y 1 A ILE 93  ? C ILE 93  
158 1 Y 1 A ASP 94  ? C ASP 94  
159 1 Y 1 A PHE 95  ? C PHE 95  
160 1 Y 1 A GLY 96  ? C GLY 96  
161 1 Y 1 A ASP 97  ? C ASP 97  
162 1 Y 1 A SER 98  ? C SER 98  
163 1 Y 1 A ALA 99  ? C ALA 99  
164 1 Y 1 A ARG 100 ? C ARG 100 
165 1 Y 1 A ALA 101 ? C ALA 101 
166 1 Y 1 A ASP 102 ? C ASP 102 
167 1 Y 1 A ASP 103 ? C ASP 103 
168 1 Y 1 A ALA 104 ? C ALA 104 
169 1 Y 1 A ARG 105 ? C ARG 105 
170 1 Y 1 A GLN 106 ? C GLN 106 
171 1 Y 1 A LEU 107 ? C LEU 107 
172 1 Y 1 A PHE 108 ? C PHE 108 
173 1 Y 1 A VAL 109 ? C VAL 109 
174 1 Y 1 A LEU 110 ? C LEU 110 
175 1 Y 1 A ALA 111 ? C ALA 111 
176 1 Y 1 A GLY 112 ? C GLY 112 
177 1 Y 1 A ALA 113 ? C ALA 113 
178 1 Y 1 A ALA 114 ? C ALA 114 
179 1 Y 1 A GLU 115 ? C GLU 115 
180 1 Y 1 A GLU 116 ? C GLU 116 
181 1 Y 1 A GLY 117 ? C GLY 117 
182 1 Y 1 A PHE 118 ? C PHE 118 
183 1 Y 1 A MET 119 ? C MET 119 
184 1 Y 1 A THR 120 ? C THR 120 
185 1 Y 1 A ALA 121 ? C ALA 121 
186 1 Y 1 A GLU 122 ? C GLU 122 
187 1 Y 1 A LEU 123 ? C LEU 123 
188 1 Y 1 A ALA 124 ? C ALA 124 
189 1 Y 1 A GLY 125 ? C GLY 125 
190 1 Y 1 A VAL 126 ? C VAL 126 
191 1 Y 1 A ILE 127 ? C ILE 127 
192 1 Y 1 A LYS 128 ? C LYS 128 
193 1 Y 1 A ARG 129 ? C ARG 129 
194 1 Y 1 A LEU 130 ? C LEU 130 
195 1 Y 1 A TRP 131 ? C TRP 131 
196 1 Y 1 A LYS 132 ? C LYS 132 
197 1 Y 1 A ASP 133 ? C ASP 133 
198 1 Y 1 A SER 134 ? C SER 134 
199 1 Y 1 A GLY 135 ? C GLY 135 
200 1 Y 1 A VAL 136 ? C VAL 136 
201 1 Y 1 A GLN 137 ? C GLN 137 
202 1 Y 1 A ALA 138 ? C ALA 138 
203 1 Y 1 A CYS 139 ? C CYS 139 
204 1 Y 1 A PHE 140 ? C PHE 140 
205 1 Y 1 A ASN 141 ? C ASN 141 
206 1 Y 1 A ARG 142 ? C ARG 142 
207 1 Y 1 A SER 143 ? C SER 143 
208 1 Y 1 A ARG 144 ? C ARG 144 
209 1 Y 1 A GLU 145 ? C GLU 145 
210 1 Y 1 A TYR 146 ? C TYR 146 
211 1 Y 1 A GLN 147 ? C GLN 147 
212 1 Y 1 A LEU 148 ? C LEU 148 
213 1 Y 1 A ASN 149 ? C ASN 149 
214 1 Y 1 A ASP 150 ? C ASP 150 
215 1 Y 1 A SER 151 ? C SER 151 
216 1 Y 1 A ALA 152 ? C ALA 152 
217 1 Y 1 A ALA 153 ? C ALA 153 
218 1 Y 1 A TYR 154 ? C TYR 154 
219 1 Y 1 A TYR 155 ? C TYR 155 
220 1 Y 1 A LEU 156 ? C LEU 156 
221 1 Y 1 A ASN 157 ? C ASN 157 
222 1 Y 1 A ASP 158 ? C ASP 158 
223 1 Y 1 A LEU 159 ? C LEU 159 
224 1 Y 1 A ASP 160 ? C ASP 160 
225 1 Y 1 A ARG 161 ? C ARG 161 
226 1 Y 1 A ILE 162 ? C ILE 162 
227 1 Y 1 A ALA 163 ? C ALA 163 
228 1 Y 1 A GLN 164 ? C GLN 164 
229 1 Y 1 A PRO 165 ? C PRO 165 
230 1 Y 1 A ASN 166 ? C ASN 166 
231 1 Y 1 A TYR 167 ? C TYR 167 
232 1 Y 1 A ILE 168 ? C ILE 168 
233 1 Y 1 A PRO 169 ? C PRO 169 
234 1 Y 1 A THR 170 ? C THR 170 
235 1 Y 1 A GLN 171 ? C GLN 171 
236 1 Y 1 A GLN 172 ? C GLN 172 
237 1 Y 1 A ASP 173 ? C ASP 173 
238 1 Y 1 A VAL 174 ? C VAL 174 
239 1 Y 1 A LEU 175 ? C LEU 175 
240 1 Y 1 A ARG 176 ? C ARG 176 
241 1 Y 1 A THR 177 ? C THR 177 
242 1 Y 1 A ARG 178 ? C ARG 178 
243 1 Y 1 A VAL 179 ? C VAL 179 
244 1 Y 1 A LYS 180 ? C LYS 180 
245 1 Y 1 A THR 181 ? C THR 181 
246 1 Y 1 B MET -17 ? D MET 1   
247 1 Y 1 B HIS -16 ? D HIS 2   
248 1 Y 1 B HIS -15 ? D HIS 3   
249 1 Y 1 B HIS -14 ? D HIS 4   
250 1 Y 1 B HIS -13 ? D HIS 5   
251 1 Y 1 B HIS -12 ? D HIS 6   
252 1 Y 1 B HIS -11 ? D HIS 7   
253 1 Y 1 B LEU -10 ? D LEU 8   
254 1 Y 1 B GLU -9  ? D GLU 9   
255 1 Y 1 B VAL -8  ? D VAL 10  
256 1 Y 1 B LEU -7  ? D LEU 11  
257 1 Y 1 B PHE -6  ? D PHE 12  
258 1 Y 1 B GLN -5  ? D GLN 13  
259 1 Y 1 B GLY -4  ? D GLY 14  
260 1 Y 1 B PRO -3  ? D PRO 15  
261 1 Y 1 B GLY -2  ? D GLY 16  
262 1 Y 1 B SER -1  ? D SER 17  
263 1 Y 1 B SER 0   ? D SER 18  
264 1 Y 1 B GLY 1   ? D GLY 19  
265 1 Y 1 B SER 2   ? D SER 20  
266 1 Y 1 C MET 1   ? E MET 1   
267 1 Y 1 C ALA 2   ? E ALA 2   
268 1 Y 1 C SER 3   ? E SER 3   
269 1 Y 1 C ASN 4   ? E ASN 4   
270 1 Y 1 C ASN 5   ? E ASN 5   
271 1 Y 1 C THR 6   ? E THR 6   
272 1 Y 1 C GLU 63  ? E GLU 63  
273 1 Y 1 C LYS 64  ? E LYS 64  
274 1 Y 1 C LYS 65  ? E LYS 65  
275 1 Y 1 C PHE 66  ? E PHE 66  
276 1 Y 1 C PHE 67  ? E PHE 67  
277 1 Y 1 C CYS 68  ? E CYS 68  
278 1 Y 1 C ALA 69  ? E ALA 69  
279 1 Y 1 C ILE 70  ? E ILE 70  
280 1 Y 1 C LEU 71  ? E LEU 71  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
XOT C1   C N R 388 
XOT C2   C N N 389 
XOT C3   C Y N 390 
XOT C4   C Y N 391 
XOT C5   C Y N 392 
XOT C6   C N N 393 
XOT C7   C N R 394 
XOT C8   C N N 395 
XOT N1   N Y N 396 
XOT N2   N Y N 397 
XOT O1   O N N 398 
XOT O2   O N N 399 
XOT H1   H N N 400 
XOT H2   H N N 401 
XOT H3   H N N 402 
XOT H4   H N N 403 
XOT H5   H N N 404 
XOT H6   H N N 405 
XOT H7   H N N 406 
XOT H8   H N N 407 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
XOT C7  C8   sing N N 374 
XOT C7  C1   sing N N 375 
XOT C7  C4   sing N N 376 
XOT C8  C1   sing N N 377 
XOT C1  C2   sing N N 378 
XOT C4  N1   sing Y N 379 
XOT C4  C3   doub Y N 380 
XOT N1  N2   sing Y N 381 
XOT C2  C3   sing N N 382 
XOT C3  C5   sing Y N 383 
XOT N2  C5   doub Y N 384 
XOT C5  C6   sing N N 385 
XOT C6  O1   doub N N 386 
XOT C6  O2   sing N N 387 
XOT C1  H1   sing N N 388 
XOT C2  H2   sing N N 389 
XOT C2  H3   sing N N 390 
XOT C7  H4   sing N N 391 
XOT C8  H5   sing N N 392 
XOT C8  H6   sing N N 393 
XOT N1  H7   sing N N 394 
XOT O2  H8   sing N N 395 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-30 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UTD 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'CryoEM Structure of HCA2-Gi1 in complex with MK-1903' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         48 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?      ? 
MASKING                    ? 3  ? ? ? ?      ? 
'CTF CORRECTION'           ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?      ? 
'MODEL FITTING'            ? 7  ? 1 ? ?      ? 
OTHER                      ? 8  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? ?      ? 
CLASSIFICATION             ? 11 1 ? ? ?      ? 
RECONSTRUCTION             ? 12 1 ? ? ?      ? 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX ? 
# 
_em_specimen.concentration           3.5 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Institute of Mental Health (NIH/NIMH)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           5R01MH112205 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8UTD 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLN A 1 12  ? 144.302 168.136 101.630 1.00 99.11  ? 7   GLN R N   1 
ATOM   2    C CA  . GLN A 1 12  ? 145.306 167.187 101.164 1.00 96.94  ? 7   GLN R CA  1 
ATOM   3    C C   . GLN A 1 12  ? 146.703 167.627 101.577 1.00 93.11  ? 7   GLN R C   1 
ATOM   4    O O   . GLN A 1 12  ? 147.617 166.810 101.663 1.00 94.41  ? 7   GLN R O   1 
ATOM   5    C CB  . GLN A 1 12  ? 145.237 167.025 99.642  1.00 98.97  ? 7   GLN R CB  1 
ATOM   6    C CG  . GLN A 1 12  ? 145.675 168.251 98.853  1.00 97.95  ? 7   GLN R CG  1 
ATOM   7    C CD  . GLN A 1 12  ? 144.621 169.341 98.826  1.00 100.15 ? 7   GLN R CD  1 
ATOM   8    O OE1 . GLN A 1 12  ? 143.515 169.140 98.323  1.00 101.40 ? 7   GLN R OE1 1 
ATOM   9    N NE2 . GLN A 1 12  ? 144.958 170.504 99.371  1.00 98.97  ? 7   GLN R NE2 1 
ATOM   10   N N   . ASP A 1 13  ? 146.861 168.929 101.824 1.00 92.93  ? 8   ASP R N   1 
ATOM   11   C CA  . ASP A 1 13  ? 148.165 169.454 102.216 1.00 95.30  ? 8   ASP R CA  1 
ATOM   12   C C   . ASP A 1 13  ? 148.613 168.877 103.552 1.00 100.16 ? 8   ASP R C   1 
ATOM   13   O O   . ASP A 1 13  ? 149.773 168.475 103.705 1.00 100.59 ? 8   ASP R O   1 
ATOM   14   C CB  . ASP A 1 13  ? 148.120 170.981 102.280 1.00 94.89  ? 8   ASP R CB  1 
ATOM   15   C CG  . ASP A 1 13  ? 147.976 171.619 100.914 1.00 97.10  ? 8   ASP R CG  1 
ATOM   16   O OD1 . ASP A 1 13  ? 146.906 171.459 100.292 1.00 99.10  ? 8   ASP R OD1 1 
ATOM   17   O OD2 . ASP A 1 13  ? 148.933 172.283 100.464 1.00 96.35  ? 8   ASP R OD2 1 
ATOM   18   N N   . HIS A 1 14  ? 147.702 168.821 104.529 1.00 79.55  ? 9   HIS R N   1 
ATOM   19   C CA  . HIS A 1 14  ? 148.029 168.385 105.889 1.00 64.85  ? 9   HIS R CA  1 
ATOM   20   C C   . HIS A 1 14  ? 149.248 169.132 106.417 1.00 59.23  ? 9   HIS R C   1 
ATOM   21   O O   . HIS A 1 14  ? 150.086 168.570 107.123 1.00 65.44  ? 9   HIS R O   1 
ATOM   22   C CB  . HIS A 1 14  ? 148.260 166.874 105.946 1.00 69.31  ? 9   HIS R CB  1 
ATOM   23   C CG  . HIS A 1 14  ? 147.001 166.067 105.985 1.00 67.01  ? 9   HIS R CG  1 
ATOM   24   N ND1 . HIS A 1 14  ? 146.218 165.962 107.113 1.00 69.01  ? 9   HIS R ND1 1 
ATOM   25   C CD2 . HIS A 1 14  ? 146.401 165.308 105.038 1.00 66.72  ? 9   HIS R CD2 1 
ATOM   26   C CE1 . HIS A 1 14  ? 145.185 165.179 106.858 1.00 70.25  ? 9   HIS R CE1 1 
ATOM   27   N NE2 . HIS A 1 14  ? 145.273 164.768 105.606 1.00 67.18  ? 9   HIS R NE2 1 
ATOM   28   N N   . PHE A 1 15  ? 149.343 170.414 106.076 1.00 72.06  ? 10  PHE R N   1 
ATOM   29   C CA  . PHE A 1 15  ? 150.589 171.155 106.198 1.00 78.72  ? 10  PHE R CA  1 
ATOM   30   C C   . PHE A 1 15  ? 150.417 172.341 107.139 1.00 75.77  ? 10  PHE R C   1 
ATOM   31   O O   . PHE A 1 15  ? 150.803 173.466 106.808 1.00 82.31  ? 10  PHE R O   1 
ATOM   32   C CB  . PHE A 1 15  ? 151.048 171.610 104.807 1.00 89.23  ? 10  PHE R CB  1 
ATOM   33   C CG  . PHE A 1 15  ? 152.430 172.208 104.768 1.00 88.19  ? 10  PHE R CG  1 
ATOM   34   C CD1 . PHE A 1 15  ? 153.304 172.065 105.831 1.00 82.11  ? 10  PHE R CD1 1 
ATOM   35   C CD2 . PHE A 1 15  ? 152.851 172.917 103.656 1.00 83.80  ? 10  PHE R CD2 1 
ATOM   36   C CE1 . PHE A 1 15  ? 154.561 172.616 105.786 1.00 82.34  ? 10  PHE R CE1 1 
ATOM   37   C CE2 . PHE A 1 15  ? 154.113 173.471 103.606 1.00 84.25  ? 10  PHE R CE2 1 
ATOM   38   C CZ  . PHE A 1 15  ? 154.969 173.319 104.674 1.00 85.24  ? 10  PHE R CZ  1 
ATOM   39   N N   . LEU A 1 16  ? 149.812 172.112 108.300 1.00 77.44  ? 11  LEU R N   1 
ATOM   40   C CA  . LEU A 1 16  ? 149.762 173.153 109.314 1.00 86.88  ? 11  LEU R CA  1 
ATOM   41   C C   . LEU A 1 16  ? 151.180 173.531 109.729 1.00 90.24  ? 11  LEU R C   1 
ATOM   42   O O   . LEU A 1 16  ? 151.889 172.744 110.362 1.00 97.27  ? 11  LEU R O   1 
ATOM   43   C CB  . LEU A 1 16  ? 148.949 172.676 110.518 1.00 86.92  ? 11  LEU R CB  1 
ATOM   44   C CG  . LEU A 1 16  ? 149.128 173.417 111.843 1.00 90.40  ? 11  LEU R CG  1 
ATOM   45   C CD1 . LEU A 1 16  ? 148.377 174.738 111.827 1.00 88.53  ? 11  LEU R CD1 1 
ATOM   46   C CD2 . LEU A 1 16  ? 148.675 172.549 113.005 1.00 86.90  ? 11  LEU R CD2 1 
ATOM   47   N N   . GLU A 1 17  ? 151.594 174.741 109.361 1.00 95.29  ? 12  GLU R N   1 
ATOM   48   C CA  . GLU A 1 17  ? 152.959 175.214 109.561 1.00 98.59  ? 12  GLU R CA  1 
ATOM   49   C C   . GLU A 1 17  ? 152.928 176.349 110.571 1.00 99.16  ? 12  GLU R C   1 
ATOM   50   O O   . GLU A 1 17  ? 152.206 177.333 110.377 1.00 98.58  ? 12  GLU R O   1 
ATOM   51   C CB  . GLU A 1 17  ? 153.570 175.671 108.233 1.00 102.37 ? 12  GLU R CB  1 
ATOM   52   C CG  . GLU A 1 17  ? 154.513 176.867 108.318 1.00 105.38 ? 12  GLU R CG  1 
ATOM   53   C CD  . GLU A 1 17  ? 155.793 176.562 109.070 1.00 108.15 ? 12  GLU R CD  1 
ATOM   54   O OE1 . GLU A 1 17  ? 156.631 175.805 108.536 1.00 106.08 ? 12  GLU R OE1 1 
ATOM   55   O OE2 . GLU A 1 17  ? 155.963 177.082 110.193 1.00 107.39 ? 12  GLU R OE2 1 
ATOM   56   N N   . ILE A 1 18  ? 153.696 176.211 111.652 1.00 97.98  ? 13  ILE R N   1 
ATOM   57   C CA  . ILE A 1 18  ? 153.684 177.197 112.730 1.00 96.86  ? 13  ILE R CA  1 
ATOM   58   C C   . ILE A 1 18  ? 155.097 177.410 113.252 1.00 97.48  ? 13  ILE R C   1 
ATOM   59   O O   . ILE A 1 18  ? 155.860 176.454 113.422 1.00 96.82  ? 13  ILE R O   1 
ATOM   60   C CB  . ILE A 1 18  ? 152.736 176.792 113.886 1.00 98.54  ? 13  ILE R CB  1 
ATOM   61   C CG1 . ILE A 1 18  ? 153.216 175.513 114.580 1.00 92.93  ? 13  ILE R CG1 1 
ATOM   62   C CG2 . ILE A 1 18  ? 151.294 176.663 113.409 1.00 99.24  ? 13  ILE R CG2 1 
ATOM   63   C CD1 . ILE A 1 18  ? 152.247 174.977 115.609 1.00 92.14  ? 13  ILE R CD1 1 
ATOM   64   N N   . ASP A 1 19  ? 155.441 178.677 113.500 1.00 104.69 ? 14  ASP R N   1 
ATOM   65   C CA  . ASP A 1 19  ? 156.643 179.056 114.248 1.00 106.06 ? 14  ASP R CA  1 
ATOM   66   C C   . ASP A 1 19  ? 157.920 178.514 113.608 1.00 106.18 ? 14  ASP R C   1 
ATOM   67   O O   . ASP A 1 19  ? 158.811 178.012 114.296 1.00 104.72 ? 14  ASP R O   1 
ATOM   68   C CB  . ASP A 1 19  ? 156.536 178.604 115.705 1.00 102.65 ? 14  ASP R CB  1 
ATOM   69   C CG  . ASP A 1 19  ? 155.194 178.942 116.321 1.00 103.68 ? 14  ASP R CG  1 
ATOM   70   O OD1 . ASP A 1 19  ? 154.441 179.729 115.711 1.00 103.34 ? 14  ASP R OD1 1 
ATOM   71   O OD2 . ASP A 1 19  ? 154.889 178.420 117.414 1.00 104.79 ? 14  ASP R OD2 1 
ATOM   72   N N   . LYS A 1 20  ? 158.020 178.642 112.284 1.00 105.83 ? 15  LYS R N   1 
ATOM   73   C CA  . LYS A 1 20  ? 159.147 178.103 111.518 1.00 104.62 ? 15  LYS R CA  1 
ATOM   74   C C   . LYS A 1 20  ? 159.316 176.609 111.804 1.00 103.00 ? 15  LYS R C   1 
ATOM   75   O O   . LYS A 1 20  ? 160.417 176.103 112.032 1.00 98.75  ? 15  LYS R O   1 
ATOM   76   C CB  . LYS A 1 20  ? 160.431 178.896 111.797 1.00 102.54 ? 15  LYS R CB  1 
ATOM   77   C CG  . LYS A 1 20  ? 161.660 178.501 110.974 1.00 104.73 ? 15  LYS R CG  1 
ATOM   78   C CD  . LYS A 1 20  ? 161.313 178.251 109.512 1.00 107.30 ? 15  LYS R CD  1 
ATOM   79   C CE  . LYS A 1 20  ? 162.230 177.195 108.908 1.00 104.61 ? 15  LYS R CE  1 
ATOM   80   N NZ  . LYS A 1 20  ? 161.820 176.796 107.533 1.00 99.36  ? 15  LYS R NZ  1 
ATOM   81   N N   . LYS A 1 21  ? 158.191 175.901 111.830 1.00 109.31 ? 16  LYS R N   1 
ATOM   82   C CA  . LYS A 1 21  ? 158.171 174.449 111.926 1.00 107.70 ? 16  LYS R CA  1 
ATOM   83   C C   . LYS A 1 21  ? 157.085 173.925 111.003 1.00 108.37 ? 16  LYS R C   1 
ATOM   84   O O   . LYS A 1 21  ? 155.917 174.320 111.119 1.00 109.74 ? 16  LYS R O   1 
ATOM   85   C CB  . LYS A 1 21  ? 157.925 173.957 113.362 1.00 110.53 ? 16  LYS R CB  1 
ATOM   86   C CG  . LYS A 1 21  ? 158.337 174.917 114.466 1.00 111.26 ? 16  LYS R CG  1 
ATOM   87   C CD  . LYS A 1 21  ? 158.214 174.275 115.838 1.00 109.52 ? 16  LYS R CD  1 
ATOM   88   C CE  . LYS A 1 21  ? 159.263 173.195 116.039 1.00 107.48 ? 16  LYS R CE  1 
ATOM   89   N NZ  . LYS A 1 21  ? 159.069 172.468 117.324 1.00 107.92 ? 16  LYS R NZ  1 
ATOM   90   N N   . ASN A 1 22  ? 157.480 173.043 110.088 1.00 105.73 ? 17  ASN R N   1 
ATOM   91   C CA  . ASN A 1 22  ? 156.563 172.396 109.159 1.00 109.10 ? 17  ASN R CA  1 
ATOM   92   C C   . ASN A 1 22  ? 156.119 171.075 109.775 1.00 106.52 ? 17  ASN R C   1 
ATOM   93   O O   . ASN A 1 22  ? 156.925 170.151 109.925 1.00 107.84 ? 17  ASN R O   1 
ATOM   94   C CB  . ASN A 1 22  ? 157.240 172.184 107.809 1.00 106.81 ? 17  ASN R CB  1 
ATOM   95   C CG  . ASN A 1 22  ? 157.448 173.480 107.056 1.00 104.60 ? 17  ASN R CG  1 
ATOM   96   O OD1 . ASN A 1 22  ? 156.510 174.039 106.492 1.00 101.59 ? 17  ASN R OD1 1 
ATOM   97   N ND2 . ASN A 1 22  ? 158.684 173.966 107.043 1.00 104.79 ? 17  ASN R ND2 1 
ATOM   98   N N   . CYS A 1 23  ? 154.840 170.983 110.128 1.00 80.33  ? 18  CYS R N   1 
ATOM   99   C CA  . CYS A 1 23  ? 154.337 169.870 110.914 1.00 70.34  ? 18  CYS R CA  1 
ATOM   100  C C   . CYS A 1 23  ? 153.092 169.290 110.264 1.00 69.80  ? 18  CYS R C   1 
ATOM   101  O O   . CYS A 1 23  ? 152.323 170.001 109.612 1.00 88.90  ? 18  CYS R O   1 
ATOM   102  C CB  . CYS A 1 23  ? 154.032 170.314 112.350 1.00 80.46  ? 18  CYS R CB  1 
ATOM   103  S SG  . CYS A 1 23  ? 155.267 171.458 113.039 1.00 98.49  ? 18  CYS R SG  1 
ATOM   104  N N   . CYS A 1 24  ? 152.902 167.987 110.445 1.00 58.72  ? 19  CYS R N   1 
ATOM   105  C CA  . CYS A 1 24  ? 151.751 167.274 109.905 1.00 68.92  ? 19  CYS R CA  1 
ATOM   106  C C   . CYS A 1 24  ? 150.841 166.865 111.055 1.00 76.51  ? 19  CYS R C   1 
ATOM   107  O O   . CYS A 1 24  ? 151.289 166.213 112.004 1.00 88.97  ? 19  CYS R O   1 
ATOM   108  C CB  . CYS A 1 24  ? 152.189 166.046 109.107 1.00 75.66  ? 19  CYS R CB  1 
ATOM   109  S SG  . CYS A 1 24  ? 153.557 166.330 107.960 1.00 101.94 ? 19  CYS R SG  1 
ATOM   110  N N   . VAL A 1 25  ? 149.570 167.247 110.968 1.00 58.37  ? 20  VAL R N   1 
ATOM   111  C CA  . VAL A 1 25  ? 148.564 166.902 111.966 1.00 50.74  ? 20  VAL R CA  1 
ATOM   112  C C   . VAL A 1 25  ? 147.463 166.129 111.261 1.00 52.63  ? 20  VAL R C   1 
ATOM   113  O O   . VAL A 1 25  ? 146.861 166.629 110.303 1.00 58.12  ? 20  VAL R O   1 
ATOM   114  C CB  . VAL A 1 25  ? 147.999 168.146 112.665 1.00 65.30  ? 20  VAL R CB  1 
ATOM   115  C CG1 . VAL A 1 25  ? 146.721 167.794 113.406 1.00 66.66  ? 20  VAL R CG1 1 
ATOM   116  C CG2 . VAL A 1 25  ? 149.031 168.733 113.615 1.00 68.97  ? 20  VAL R CG2 1 
ATOM   117  N N   . PHE A 1 26  ? 147.194 164.917 111.737 1.00 72.54  ? 21  PHE R N   1 
ATOM   118  C CA  . PHE A 1 26  ? 146.305 163.982 111.064 1.00 74.24  ? 21  PHE R CA  1 
ATOM   119  C C   . PHE A 1 26  ? 145.029 163.792 111.870 1.00 75.73  ? 21  PHE R C   1 
ATOM   120  O O   . PHE A 1 26  ? 145.059 163.763 113.104 1.00 86.19  ? 21  PHE R O   1 
ATOM   121  C CB  . PHE A 1 26  ? 146.993 162.631 110.858 1.00 74.53  ? 21  PHE R CB  1 
ATOM   122  C CG  . PHE A 1 26  ? 147.883 162.582 109.653 1.00 73.00  ? 21  PHE R CG  1 
ATOM   123  C CD1 . PHE A 1 26  ? 148.982 163.414 109.553 1.00 77.17  ? 21  PHE R CD1 1 
ATOM   124  C CD2 . PHE A 1 26  ? 147.622 161.700 108.621 1.00 77.92  ? 21  PHE R CD2 1 
ATOM   125  C CE1 . PHE A 1 26  ? 149.803 163.371 108.445 1.00 81.92  ? 21  PHE R CE1 1 
ATOM   126  C CE2 . PHE A 1 26  ? 148.438 161.651 107.511 1.00 81.46  ? 21  PHE R CE2 1 
ATOM   127  C CZ  . PHE A 1 26  ? 149.531 162.487 107.422 1.00 84.41  ? 21  PHE R CZ  1 
ATOM   128  N N   . ARG A 1 27  ? 143.910 163.661 111.164 1.00 91.07  ? 22  ARG R N   1 
ATOM   129  C CA  . ARG A 1 27  ? 142.598 163.454 111.769 1.00 97.83  ? 22  ARG R CA  1 
ATOM   130  C C   . ARG A 1 27  ? 142.025 162.170 111.180 1.00 103.01 ? 22  ARG R C   1 
ATOM   131  O O   . ARG A 1 27  ? 141.322 162.197 110.166 1.00 104.04 ? 22  ARG R O   1 
ATOM   132  C CB  . ARG A 1 27  ? 141.679 164.646 111.520 1.00 102.94 ? 22  ARG R CB  1 
ATOM   133  C CG  . ARG A 1 27  ? 142.079 165.912 112.259 1.00 104.41 ? 22  ARG R CG  1 
ATOM   134  C CD  . ARG A 1 27  ? 141.261 167.101 111.785 1.00 104.94 ? 22  ARG R CD  1 
ATOM   135  N NE  . ARG A 1 27  ? 139.871 167.008 112.213 1.00 105.82 ? 22  ARG R NE  1 
ATOM   136  C CZ  . ARG A 1 27  ? 138.907 167.825 111.812 1.00 103.77 ? 22  ARG R CZ  1 
ATOM   137  N NH1 . ARG A 1 27  ? 139.147 168.815 110.967 1.00 101.04 ? 22  ARG R NH1 1 
ATOM   138  N NH2 . ARG A 1 27  ? 137.672 167.644 112.268 1.00 104.97 ? 22  ARG R NH2 1 
ATOM   139  N N   . ASP A 1 28  ? 142.327 161.045 111.818 1.00 115.61 ? 23  ASP R N   1 
ATOM   140  C CA  . ASP A 1 28  ? 141.897 159.740 111.343 1.00 113.71 ? 23  ASP R CA  1 
ATOM   141  C C   . ASP A 1 28  ? 140.715 159.236 112.162 1.00 109.81 ? 23  ASP R C   1 
ATOM   142  O O   . ASP A 1 28  ? 140.518 159.629 113.314 1.00 109.23 ? 23  ASP R O   1 
ATOM   143  C CB  . ASP A 1 28  ? 143.045 158.733 111.408 1.00 110.62 ? 23  ASP R CB  1 
ATOM   144  C CG  . ASP A 1 28  ? 143.004 157.729 110.274 1.00 111.53 ? 23  ASP R CG  1 
ATOM   145  O OD1 . ASP A 1 28  ? 142.159 156.811 110.321 1.00 112.23 ? 23  ASP R OD1 1 
ATOM   146  O OD2 . ASP A 1 28  ? 143.817 157.859 109.336 1.00 111.80 ? 23  ASP R OD2 1 
ATOM   147  N N   . ASP A 1 29  ? 139.925 158.356 111.546 1.00 114.48 ? 24  ASP R N   1 
ATOM   148  C CA  . ASP A 1 29  ? 138.737 157.834 112.211 1.00 117.56 ? 24  ASP R CA  1 
ATOM   149  C C   . ASP A 1 29  ? 139.091 156.841 113.312 1.00 117.56 ? 24  ASP R C   1 
ATOM   150  O O   . ASP A 1 29  ? 138.401 156.781 114.338 1.00 119.92 ? 24  ASP R O   1 
ATOM   151  C CB  . ASP A 1 29  ? 137.814 157.178 111.185 1.00 116.65 ? 24  ASP R CB  1 
ATOM   152  C CG  . ASP A 1 29  ? 137.188 158.182 110.240 1.00 116.71 ? 24  ASP R CG  1 
ATOM   153  O OD1 . ASP A 1 29  ? 137.035 159.356 110.634 1.00 117.19 ? 24  ASP R OD1 1 
ATOM   154  O OD2 . ASP A 1 29  ? 136.853 157.798 109.100 1.00 115.52 ? 24  ASP R OD2 1 
ATOM   155  N N   . PHE A 1 30  ? 140.157 156.059 113.119 1.00 112.73 ? 25  PHE R N   1 
ATOM   156  C CA  . PHE A 1 30  ? 140.475 154.998 114.068 1.00 110.26 ? 25  PHE R CA  1 
ATOM   157  C C   . PHE A 1 30  ? 140.840 155.549 115.439 1.00 112.86 ? 25  PHE R C   1 
ATOM   158  O O   . PHE A 1 30  ? 140.650 154.859 116.445 1.00 115.53 ? 25  PHE R O   1 
ATOM   159  C CB  . PHE A 1 30  ? 141.609 154.129 113.528 1.00 110.43 ? 25  PHE R CB  1 
ATOM   160  C CG  . PHE A 1 30  ? 141.140 152.976 112.688 1.00 114.69 ? 25  PHE R CG  1 
ATOM   161  C CD1 . PHE A 1 30  ? 139.931 153.037 112.016 1.00 113.39 ? 25  PHE R CD1 1 
ATOM   162  C CD2 . PHE A 1 30  ? 141.910 151.831 112.570 1.00 115.64 ? 25  PHE R CD2 1 
ATOM   163  C CE1 . PHE A 1 30  ? 139.499 151.979 111.241 1.00 112.87 ? 25  PHE R CE1 1 
ATOM   164  C CE2 . PHE A 1 30  ? 141.482 150.768 111.797 1.00 113.90 ? 25  PHE R CE2 1 
ATOM   165  C CZ  . PHE A 1 30  ? 140.275 150.843 111.132 1.00 113.63 ? 25  PHE R CZ  1 
ATOM   166  N N   . ILE A 1 31  ? 141.350 156.781 115.505 1.00 106.88 ? 26  ILE R N   1 
ATOM   167  C CA  . ILE A 1 31  ? 141.698 157.366 116.798 1.00 108.12 ? 26  ILE R CA  1 
ATOM   168  C C   . ILE A 1 31  ? 140.453 157.499 117.666 1.00 105.40 ? 26  ILE R C   1 
ATOM   169  O O   . ILE A 1 31  ? 140.412 157.027 118.811 1.00 108.59 ? 26  ILE R O   1 
ATOM   170  C CB  . ILE A 1 31  ? 142.395 158.724 116.601 1.00 109.07 ? 26  ILE R CB  1 
ATOM   171  C CG1 . ILE A 1 31  ? 143.859 158.522 116.204 1.00 111.92 ? 26  ILE R CG1 1 
ATOM   172  C CG2 . ILE A 1 31  ? 142.296 159.569 117.862 1.00 108.54 ? 26  ILE R CG2 1 
ATOM   173  C CD1 . ILE A 1 31  ? 144.518 159.767 115.653 1.00 109.54 ? 26  ILE R CD1 1 
ATOM   174  N N   . VAL A 1 32  ? 139.409 158.123 117.121 1.00 103.34 ? 27  VAL R N   1 
ATOM   175  C CA  . VAL A 1 32  ? 138.155 158.236 117.852 1.00 108.61 ? 27  VAL R CA  1 
ATOM   176  C C   . VAL A 1 32  ? 137.520 156.865 118.023 1.00 110.77 ? 27  VAL R C   1 
ATOM   177  O O   . VAL A 1 32  ? 136.803 156.619 119.001 1.00 113.10 ? 27  VAL R O   1 
ATOM   178  C CB  . VAL A 1 32  ? 137.212 159.219 117.134 1.00 114.03 ? 27  VAL R CB  1 
ATOM   179  C CG1 . VAL A 1 32  ? 135.943 159.442 117.945 1.00 113.92 ? 27  VAL R CG1 1 
ATOM   180  C CG2 . VAL A 1 32  ? 137.922 160.537 116.874 1.00 113.29 ? 27  VAL R CG2 1 
ATOM   181  N N   . LYS A 1 33  ? 137.771 155.949 117.085 1.00 115.61 ? 28  LYS R N   1 
ATOM   182  C CA  . LYS A 1 33  ? 137.180 154.619 117.180 1.00 116.66 ? 28  LYS R CA  1 
ATOM   183  C C   . LYS A 1 33  ? 137.722 153.842 118.375 1.00 117.96 ? 28  LYS R C   1 
ATOM   184  O O   . LYS A 1 33  ? 136.968 153.130 119.049 1.00 119.20 ? 28  LYS R O   1 
ATOM   185  C CB  . LYS A 1 33  ? 137.421 153.846 115.884 1.00 114.92 ? 28  LYS R CB  1 
ATOM   186  N N   . VAL A 1 34  ? 139.019 153.960 118.657 1.00 114.55 ? 29  VAL R N   1 
ATOM   187  C CA  . VAL A 1 34  ? 139.667 153.068 119.604 1.00 113.54 ? 29  VAL R CA  1 
ATOM   188  C C   . VAL A 1 34  ? 139.991 153.727 120.945 1.00 111.09 ? 29  VAL R C   1 
ATOM   189  O O   . VAL A 1 34  ? 139.961 153.039 121.973 1.00 110.91 ? 29  VAL R O   1 
ATOM   190  C CB  . VAL A 1 34  ? 140.936 152.437 118.990 1.00 111.50 ? 29  VAL R CB  1 
ATOM   191  C CG1 . VAL A 1 34  ? 140.620 151.822 117.634 1.00 110.53 ? 29  VAL R CG1 1 
ATOM   192  C CG2 . VAL A 1 34  ? 142.057 153.457 118.876 1.00 110.97 ? 29  VAL R CG2 1 
ATOM   193  N N   . LEU A 1 35  ? 140.295 155.026 120.983 1.00 113.00 ? 30  LEU R N   1 
ATOM   194  C CA  . LEU A 1 35  ? 140.883 155.575 122.204 1.00 115.57 ? 30  LEU R CA  1 
ATOM   195  C C   . LEU A 1 35  ? 139.900 155.840 123.350 1.00 115.50 ? 30  LEU R C   1 
ATOM   196  O O   . LEU A 1 35  ? 140.226 155.512 124.500 1.00 120.32 ? 30  LEU R O   1 
ATOM   197  C CB  . LEU A 1 35  ? 141.655 156.853 121.867 1.00 115.43 ? 30  LEU R CB  1 
ATOM   198  C CG  . LEU A 1 35  ? 142.862 156.636 120.951 1.00 112.97 ? 30  LEU R CG  1 
ATOM   199  C CD1 . LEU A 1 35  ? 143.705 157.893 120.863 1.00 112.94 ? 30  LEU R CD1 1 
ATOM   200  C CD2 . LEU A 1 35  ? 143.701 155.466 121.432 1.00 111.93 ? 30  LEU R CD2 1 
ATOM   201  N N   . PRO A 1 36  ? 138.729 156.438 123.115 1.00 117.47 ? 31  PRO R N   1 
ATOM   202  C CA  . PRO A 1 36  ? 137.840 156.808 124.240 1.00 116.81 ? 31  PRO R CA  1 
ATOM   203  C C   . PRO A 1 36  ? 137.459 155.634 125.131 1.00 119.09 ? 31  PRO R C   1 
ATOM   204  O O   . PRO A 1 36  ? 137.395 155.804 126.359 1.00 121.46 ? 31  PRO R O   1 
ATOM   205  C CB  . PRO A 1 36  ? 136.609 157.398 123.536 1.00 120.55 ? 31  PRO R CB  1 
ATOM   206  C CG  . PRO A 1 36  ? 137.150 157.959 122.284 1.00 121.73 ? 31  PRO R CG  1 
ATOM   207  C CD  . PRO A 1 36  ? 138.239 157.017 121.847 1.00 121.32 ? 31  PRO R CD  1 
ATOM   208  N N   . PRO A 1 37  ? 137.180 154.436 124.590 1.00 120.06 ? 32  PRO R N   1 
ATOM   209  C CA  . PRO A 1 37  ? 136.807 153.333 125.501 1.00 123.75 ? 32  PRO R CA  1 
ATOM   210  C C   . PRO A 1 37  ? 137.925 152.919 126.444 1.00 123.50 ? 32  PRO R C   1 
ATOM   211  O O   . PRO A 1 37  ? 137.693 152.754 127.654 1.00 122.02 ? 32  PRO R O   1 
ATOM   212  C CB  . PRO A 1 37  ? 136.415 152.202 124.537 1.00 121.56 ? 32  PRO R CB  1 
ATOM   213  C CG  . PRO A 1 37  ? 136.060 152.883 123.277 1.00 119.85 ? 32  PRO R CG  1 
ATOM   214  C CD  . PRO A 1 37  ? 137.011 154.027 123.182 1.00 115.52 ? 32  PRO R CD  1 
ATOM   215  N N   . VAL A 1 38  ? 139.140 152.736 125.922 1.00 114.91 ? 33  VAL R N   1 
ATOM   216  C CA  . VAL A 1 38  ? 140.256 152.375 126.787 1.00 110.61 ? 33  VAL R CA  1 
ATOM   217  C C   . VAL A 1 38  ? 140.565 153.508 127.755 1.00 110.35 ? 33  VAL R C   1 
ATOM   218  O O   . VAL A 1 38  ? 140.943 153.261 128.908 1.00 112.75 ? 33  VAL R O   1 
ATOM   219  C CB  . VAL A 1 38  ? 141.485 151.965 125.949 1.00 112.86 ? 33  VAL R CB  1 
ATOM   220  C CG1 . VAL A 1 38  ? 142.262 153.176 125.456 1.00 110.28 ? 33  VAL R CG1 1 
ATOM   221  C CG2 . VAL A 1 38  ? 142.388 151.039 126.752 1.00 115.20 ? 33  VAL R CG2 1 
ATOM   222  N N   . LEU A 1 39  ? 140.393 154.761 127.324 1.00 120.16 ? 34  LEU R N   1 
ATOM   223  C CA  . LEU A 1 39  ? 140.605 155.882 128.232 1.00 123.39 ? 34  LEU R CA  1 
ATOM   224  C C   . LEU A 1 39  ? 139.612 155.847 129.386 1.00 122.74 ? 34  LEU R C   1 
ATOM   225  O O   . LEU A 1 39  ? 139.984 156.084 130.540 1.00 123.43 ? 34  LEU R O   1 
ATOM   226  C CB  . LEU A 1 39  ? 140.503 157.201 127.468 1.00 126.03 ? 34  LEU R CB  1 
ATOM   227  C CG  . LEU A 1 39  ? 141.826 157.929 127.220 1.00 125.08 ? 34  LEU R CG  1 
ATOM   228  C CD1 . LEU A 1 39  ? 141.585 159.280 126.569 1.00 122.97 ? 34  LEU R CD1 1 
ATOM   229  C CD2 . LEU A 1 39  ? 142.599 158.090 128.517 1.00 122.63 ? 34  LEU R CD2 1 
ATOM   230  N N   . GLY A 1 40  ? 138.346 155.542 129.096 1.00 123.33 ? 35  GLY R N   1 
ATOM   231  C CA  . GLY A 1 40  ? 137.359 155.446 130.160 1.00 123.05 ? 35  GLY R CA  1 
ATOM   232  C C   . GLY A 1 40  ? 137.633 154.298 131.112 1.00 125.43 ? 35  GLY R C   1 
ATOM   233  O O   . GLY A 1 40  ? 137.479 154.437 132.332 1.00 128.59 ? 35  GLY R O   1 
ATOM   234  N N   . LEU A 1 41  ? 138.033 153.144 130.572 1.00 124.74 ? 36  LEU R N   1 
ATOM   235  C CA  . LEU A 1 41  ? 138.371 152.010 131.427 1.00 125.19 ? 36  LEU R CA  1 
ATOM   236  C C   . LEU A 1 41  ? 139.537 152.351 132.347 1.00 123.36 ? 36  LEU R C   1 
ATOM   237  O O   . LEU A 1 41  ? 139.503 152.066 133.553 1.00 122.41 ? 36  LEU R O   1 
ATOM   238  C CB  . LEU A 1 41  ? 138.702 150.787 130.570 1.00 126.35 ? 36  LEU R CB  1 
ATOM   239  C CG  . LEU A 1 41  ? 137.530 150.094 129.873 1.00 126.01 ? 36  LEU R CG  1 
ATOM   240  C CD1 . LEU A 1 41  ? 138.018 148.893 129.078 1.00 123.23 ? 36  LEU R CD1 1 
ATOM   241  C CD2 . LEU A 1 41  ? 136.471 149.680 130.883 1.00 123.64 ? 36  LEU R CD2 1 
ATOM   242  N N   . GLU A 1 42  ? 140.579 152.974 131.788 1.00 127.05 ? 37  GLU R N   1 
ATOM   243  C CA  . GLU A 1 42  ? 141.717 153.390 132.597 1.00 128.37 ? 37  GLU R CA  1 
ATOM   244  C C   . GLU A 1 42  ? 141.295 154.396 133.656 1.00 128.84 ? 37  GLU R C   1 
ATOM   245  O O   . GLU A 1 42  ? 141.741 154.318 134.805 1.00 129.21 ? 37  GLU R O   1 
ATOM   246  C CB  . GLU A 1 42  ? 142.811 153.977 131.706 1.00 129.82 ? 37  GLU R CB  1 
ATOM   247  C CG  . GLU A 1 42  ? 143.561 152.948 130.878 1.00 130.57 ? 37  GLU R CG  1 
ATOM   248  C CD  . GLU A 1 42  ? 144.521 153.584 129.892 1.00 130.06 ? 37  GLU R CD  1 
ATOM   249  O OE1 . GLU A 1 42  ? 144.712 154.817 129.960 1.00 129.07 ? 37  GLU R OE1 1 
ATOM   250  O OE2 . GLU A 1 42  ? 145.084 152.854 129.051 1.00 128.39 ? 37  GLU R OE2 1 
ATOM   251  N N   . PHE A 1 43  ? 140.436 155.347 133.287 1.00 134.04 ? 38  PHE R N   1 
ATOM   252  C CA  . PHE A 1 43  ? 139.946 156.327 134.249 1.00 133.20 ? 38  PHE R CA  1 
ATOM   253  C C   . PHE A 1 43  ? 139.272 155.643 135.428 1.00 132.95 ? 38  PHE R C   1 
ATOM   254  O O   . PHE A 1 43  ? 139.599 155.918 136.587 1.00 130.29 ? 38  PHE R O   1 
ATOM   255  C CB  . PHE A 1 43  ? 138.975 157.287 133.562 1.00 133.94 ? 38  PHE R CB  1 
ATOM   256  C CG  . PHE A 1 43  ? 137.867 157.780 134.452 1.00 135.07 ? 38  PHE R CG  1 
ATOM   257  C CD1 . PHE A 1 43  ? 138.130 158.662 135.488 1.00 136.10 ? 38  PHE R CD1 1 
ATOM   258  C CD2 . PHE A 1 43  ? 136.561 157.367 134.246 1.00 135.25 ? 38  PHE R CD2 1 
ATOM   259  C CE1 . PHE A 1 43  ? 137.111 159.117 136.306 1.00 136.31 ? 38  PHE R CE1 1 
ATOM   260  C CE2 . PHE A 1 43  ? 135.538 157.819 135.059 1.00 136.09 ? 38  PHE R CE2 1 
ATOM   261  C CZ  . PHE A 1 43  ? 135.813 158.696 136.091 1.00 136.32 ? 38  PHE R CZ  1 
ATOM   262  N N   . ILE A 1 44  ? 138.334 154.737 135.146 1.00 137.81 ? 39  ILE R N   1 
ATOM   263  C CA  . ILE A 1 44  ? 137.589 154.084 136.221 1.00 138.41 ? 39  ILE R CA  1 
ATOM   264  C C   . ILE A 1 44  ? 138.533 153.288 137.117 1.00 139.05 ? 39  ILE R C   1 
ATOM   265  O O   . ILE A 1 44  ? 138.513 153.422 138.351 1.00 137.22 ? 39  ILE R O   1 
ATOM   266  C CB  . ILE A 1 44  ? 136.477 153.191 135.641 1.00 135.94 ? 39  ILE R CB  1 
ATOM   267  C CG1 . ILE A 1 44  ? 135.417 154.043 134.942 1.00 135.84 ? 39  ILE R CG1 1 
ATOM   268  C CG2 . ILE A 1 44  ? 135.845 152.347 136.737 1.00 136.03 ? 39  ILE R CG2 1 
ATOM   269  C CD1 . ILE A 1 44  ? 134.470 153.246 134.069 1.00 135.72 ? 39  ILE R CD1 1 
ATOM   270  N N   . PHE A 1 45  ? 139.381 152.453 136.508 1.00 142.17 ? 40  PHE R N   1 
ATOM   271  C CA  . PHE A 1 45  ? 140.242 151.581 137.300 1.00 140.05 ? 40  PHE R CA  1 
ATOM   272  C C   . PHE A 1 45  ? 141.228 152.389 138.134 1.00 140.61 ? 40  PHE R C   1 
ATOM   273  O O   . PHE A 1 45  ? 141.413 152.121 139.329 1.00 142.97 ? 40  PHE R O   1 
ATOM   274  C CB  . PHE A 1 45  ? 140.978 150.599 136.388 1.00 140.39 ? 40  PHE R CB  1 
ATOM   275  C CG  . PHE A 1 45  ? 140.112 149.480 135.882 1.00 143.65 ? 40  PHE R CG  1 
ATOM   276  C CD1 . PHE A 1 45  ? 139.338 148.736 136.757 1.00 142.68 ? 40  PHE R CD1 1 
ATOM   277  C CD2 . PHE A 1 45  ? 140.076 149.168 134.533 1.00 143.91 ? 40  PHE R CD2 1 
ATOM   278  C CE1 . PHE A 1 45  ? 138.540 147.706 136.296 1.00 141.83 ? 40  PHE R CE1 1 
ATOM   279  C CE2 . PHE A 1 45  ? 139.280 148.139 134.066 1.00 143.30 ? 40  PHE R CE2 1 
ATOM   280  C CZ  . PHE A 1 45  ? 138.512 147.407 134.949 1.00 142.77 ? 40  PHE R CZ  1 
ATOM   281  N N   . GLY A 1 46  ? 141.812 153.400 137.497 1.00 133.83 ? 41  GLY R N   1 
ATOM   282  C CA  . GLY A 1 46  ? 142.836 154.191 138.195 1.00 134.03 ? 41  GLY R CA  1 
ATOM   283  C C   . GLY A 1 46  ? 142.273 154.928 139.391 1.00 133.90 ? 41  GLY R C   1 
ATOM   284  O O   . GLY A 1 46  ? 142.856 154.802 140.485 1.00 133.60 ? 41  GLY R O   1 
ATOM   285  N N   . LEU A 1 47  ? 141.172 155.658 139.207 1.00 135.69 ? 42  LEU R N   1 
ATOM   286  C CA  . LEU A 1 47  ? 140.719 156.506 140.337 1.00 135.92 ? 42  LEU R CA  1 
ATOM   287  C C   . LEU A 1 47  ? 140.339 155.679 141.564 1.00 135.87 ? 42  LEU R C   1 
ATOM   288  O O   . LEU A 1 47  ? 140.805 156.041 142.663 1.00 135.96 ? 42  LEU R O   1 
ATOM   289  C CB  . LEU A 1 47  ? 139.523 157.337 139.863 1.00 138.23 ? 42  LEU R CB  1 
ATOM   290  C CG  . LEU A 1 47  ? 139.048 158.408 140.842 1.00 139.10 ? 42  LEU R CG  1 
ATOM   291  C CD1 . LEU A 1 47  ? 138.508 159.620 140.101 1.00 137.01 ? 42  LEU R CD1 1 
ATOM   292  C CD2 . LEU A 1 47  ? 137.998 157.849 141.791 1.00 136.26 ? 42  LEU R CD2 1 
ATOM   293  N N   . LEU A 1 48  ? 139.587 154.588 141.400 1.00 139.40 ? 43  LEU R N   1 
ATOM   294  C CA  . LEU A 1 48  ? 139.216 153.882 142.655 1.00 141.99 ? 43  LEU R CA  1 
ATOM   295  C C   . LEU A 1 48  ? 140.468 153.311 143.327 1.00 139.22 ? 43  LEU R C   1 
ATOM   296  O O   . LEU A 1 48  ? 140.639 153.519 144.543 1.00 136.63 ? 43  LEU R O   1 
ATOM   297  C CB  . LEU A 1 48  ? 138.203 152.773 142.345 1.00 140.51 ? 43  LEU R CB  1 
ATOM   298  C CG  . LEU A 1 48  ? 136.735 153.192 142.285 1.00 139.76 ? 43  LEU R CG  1 
ATOM   299  C CD1 . LEU A 1 48  ? 136.306 153.860 143.582 1.00 139.32 ? 43  LEU R CD1 1 
ATOM   300  C CD2 . LEU A 1 48  ? 136.495 154.129 141.111 1.00 137.15 ? 43  LEU R CD2 1 
ATOM   301  N N   . GLY A 1 49  ? 141.340 152.675 142.539 1.00 132.42 ? 44  GLY R N   1 
ATOM   302  C CA  . GLY A 1 49  ? 142.500 152.028 143.170 1.00 129.82 ? 44  GLY R CA  1 
ATOM   303  C C   . GLY A 1 49  ? 143.430 153.030 143.813 1.00 131.86 ? 44  GLY R C   1 
ATOM   304  O O   . GLY A 1 49  ? 143.851 152.800 144.966 1.00 133.98 ? 44  GLY R O   1 
ATOM   305  N N   . ASN A 1 50  ? 143.711 154.125 143.102 1.00 134.51 ? 45  ASN R N   1 
ATOM   306  C CA  . ASN A 1 50  ? 144.700 155.089 143.649 1.00 135.27 ? 45  ASN R CA  1 
ATOM   307  C C   . ASN A 1 50  ? 144.131 155.693 144.932 1.00 135.34 ? 45  ASN R C   1 
ATOM   308  O O   . ASN A 1 50  ? 144.878 155.812 145.922 1.00 133.42 ? 45  ASN R O   1 
ATOM   309  C CB  . ASN A 1 50  ? 145.134 156.139 142.628 1.00 135.40 ? 45  ASN R CB  1 
ATOM   310  C CG  . ASN A 1 50  ? 146.395 156.843 143.074 1.00 135.06 ? 45  ASN R CG  1 
ATOM   311  O OD1 . ASN A 1 50  ? 147.501 156.382 142.800 1.00 132.56 ? 45  ASN R OD1 1 
ATOM   312  N ND2 . ASN A 1 50  ? 146.237 157.932 143.805 1.00 135.22 ? 45  ASN R ND2 1 
ATOM   313  N N   . GLY A 1 51  ? 142.840 156.019 144.906 1.00 137.57 ? 46  GLY R N   1 
ATOM   314  C CA  . GLY A 1 51  ? 142.204 156.630 146.083 1.00 136.80 ? 46  GLY R CA  1 
ATOM   315  C C   . GLY A 1 51  ? 142.236 155.665 147.244 1.00 135.12 ? 46  GLY R C   1 
ATOM   316  O O   . GLY A 1 51  ? 142.508 156.103 148.369 1.00 133.08 ? 46  GLY R O   1 
ATOM   317  N N   . LEU A 1 52  ? 141.993 154.384 146.965 1.00 138.54 ? 47  LEU R N   1 
ATOM   318  C CA  . LEU A 1 52  ? 141.903 153.414 148.081 1.00 139.38 ? 47  LEU R CA  1 
ATOM   319  C C   . LEU A 1 52  ? 143.261 153.401 148.772 1.00 139.26 ? 47  LEU R C   1 
ATOM   320  O O   . LEU A 1 52  ? 143.288 153.430 150.011 1.00 138.57 ? 47  LEU R O   1 
ATOM   321  C CB  . LEU A 1 52  ? 141.572 152.034 147.514 1.00 140.13 ? 47  LEU R CB  1 
ATOM   322  C CG  . LEU A 1 52  ? 141.515 150.902 148.538 1.00 139.69 ? 47  LEU R CG  1 
ATOM   323  C CD1 . LEU A 1 52  ? 140.403 151.145 149.548 1.00 138.14 ? 47  LEU R CD1 1 
ATOM   324  C CD2 . LEU A 1 52  ? 141.327 149.557 147.854 1.00 139.44 ? 47  LEU R CD2 1 
ATOM   325  N N   . ALA A 1 53  ? 144.337 153.427 147.986 1.00 144.07 ? 48  ALA R N   1 
ATOM   326  C CA  . ALA A 1 53  ? 145.673 153.496 148.612 1.00 144.62 ? 48  ALA R CA  1 
ATOM   327  C C   . ALA A 1 53  ? 145.782 154.811 149.387 1.00 145.65 ? 48  ALA R C   1 
ATOM   328  O O   . ALA A 1 53  ? 146.221 154.768 150.545 1.00 148.49 ? 48  ALA R O   1 
ATOM   329  C CB  . ALA A 1 53  ? 146.739 153.393 147.552 1.00 142.41 ? 48  ALA R CB  1 
ATOM   330  N N   . LEU A 1 54  ? 145.303 155.913 148.802 1.00 138.90 ? 49  LEU R N   1 
ATOM   331  C CA  . LEU A 1 54  ? 145.435 157.230 149.474 1.00 139.33 ? 49  LEU R CA  1 
ATOM   332  C C   . LEU A 1 54  ? 144.635 157.181 150.776 1.00 143.02 ? 49  LEU R C   1 
ATOM   333  O O   . LEU A 1 54  ? 145.141 157.674 151.801 1.00 141.96 ? 49  LEU R O   1 
ATOM   334  C CB  . LEU A 1 54  ? 144.900 158.324 148.548 1.00 139.55 ? 49  LEU R CB  1 
ATOM   335  C CG  . LEU A 1 54  ? 145.663 158.512 147.239 1.00 139.43 ? 49  LEU R CG  1 
ATOM   336  C CD1 . LEU A 1 54  ? 144.858 159.364 146.273 1.00 139.13 ? 49  LEU R CD1 1 
ATOM   337  C CD2 . LEU A 1 54  ? 147.027 159.136 147.491 1.00 138.06 ? 49  LEU R CD2 1 
ATOM   338  N N   . TRP A 1 55  ? 143.446 156.573 150.728 1.00 150.58 ? 50  TRP R N   1 
ATOM   339  C CA  . TRP A 1 55  ? 142.604 156.449 151.945 1.00 149.84 ? 50  TRP R CA  1 
ATOM   340  C C   . TRP A 1 55  ? 143.314 155.505 152.911 1.00 146.64 ? 50  TRP R C   1 
ATOM   341  O O   . TRP A 1 55  ? 143.626 155.935 154.037 1.00 145.92 ? 50  TRP R O   1 
ATOM   342  C CB  . TRP A 1 55  ? 141.202 155.936 151.603 1.00 149.40 ? 50  TRP R CB  1 
ATOM   343  C CG  . TRP A 1 55  ? 140.316 155.847 152.808 1.00 150.90 ? 50  TRP R CG  1 
ATOM   344  C CD1 . TRP A 1 55  ? 139.524 156.832 153.323 1.00 149.76 ? 50  TRP R CD1 1 
ATOM   345  C CD2 . TRP A 1 55  ? 140.159 154.712 153.678 1.00 150.72 ? 50  TRP R CD2 1 
ATOM   346  N NE1 . TRP A 1 55  ? 138.877 156.386 154.443 1.00 149.45 ? 50  TRP R NE1 1 
ATOM   347  C CE2 . TRP A 1 55  ? 139.246 155.088 154.685 1.00 149.46 ? 50  TRP R CE2 1 
ATOM   348  C CE3 . TRP A 1 55  ? 140.688 153.418 153.696 1.00 149.40 ? 50  TRP R CE3 1 
ATOM   349  C CZ2 . TRP A 1 55  ? 138.856 154.215 155.697 1.00 148.62 ? 50  TRP R CZ2 1 
ATOM   350  C CZ3 . TRP A 1 55  ? 140.303 152.556 154.698 1.00 148.72 ? 50  TRP R CZ3 1 
ATOM   351  C CH2 . TRP A 1 55  ? 139.399 152.952 155.684 1.00 148.86 ? 50  TRP R CH2 1 
ATOM   352  N N   . ILE A 1 56  ? 143.573 154.274 152.469 1.00 138.29 ? 51  ILE R N   1 
ATOM   353  C CA  . ILE A 1 56  ? 144.326 153.378 153.344 1.00 139.99 ? 51  ILE R CA  1 
ATOM   354  C C   . ILE A 1 56  ? 145.535 154.092 153.932 1.00 142.06 ? 51  ILE R C   1 
ATOM   355  O O   . ILE A 1 56  ? 145.820 153.976 155.130 1.00 144.61 ? 51  ILE R O   1 
ATOM   356  C CB  . ILE A 1 56  ? 144.734 152.103 152.583 1.00 141.33 ? 51  ILE R CB  1 
ATOM   357  C CG1 . ILE A 1 56  ? 143.494 151.296 152.189 1.00 141.57 ? 51  ILE R CG1 1 
ATOM   358  C CG2 . ILE A 1 56  ? 145.688 151.262 153.420 1.00 141.81 ? 51  ILE R CG2 1 
ATOM   359  C CD1 . ILE A 1 56  ? 143.791 149.867 151.783 1.00 141.35 ? 51  ILE R CD1 1 
ATOM   360  N N   . PHE A 1 57  ? 146.267 154.841 153.104 1.00 141.75 ? 52  PHE R N   1 
ATOM   361  C CA  . PHE A 1 57  ? 147.442 155.548 153.601 1.00 140.78 ? 52  PHE R CA  1 
ATOM   362  C C   . PHE A 1 57  ? 147.063 156.591 154.643 1.00 140.42 ? 52  PHE R C   1 
ATOM   363  O O   . PHE A 1 57  ? 147.751 156.743 155.660 1.00 139.34 ? 52  PHE R O   1 
ATOM   364  C CB  . PHE A 1 57  ? 148.193 156.203 152.442 1.00 140.58 ? 52  PHE R CB  1 
ATOM   365  C CG  . PHE A 1 57  ? 148.941 155.229 151.578 1.00 142.02 ? 52  PHE R CG  1 
ATOM   366  C CD1 . PHE A 1 57  ? 149.595 154.147 152.139 1.00 141.22 ? 52  PHE R CD1 1 
ATOM   367  C CD2 . PHE A 1 57  ? 148.994 155.400 150.205 1.00 140.59 ? 52  PHE R CD2 1 
ATOM   368  C CE1 . PHE A 1 57  ? 150.284 153.251 151.347 1.00 139.76 ? 52  PHE R CE1 1 
ATOM   369  C CE2 . PHE A 1 57  ? 149.681 154.508 149.408 1.00 139.86 ? 52  PHE R CE2 1 
ATOM   370  C CZ  . PHE A 1 57  ? 150.326 153.432 149.980 1.00 139.99 ? 52  PHE R CZ  1 
ATOM   371  N N   . CYS A 1 58  ? 145.970 157.321 154.411 1.00 146.72 ? 53  CYS R N   1 
ATOM   372  C CA  . CYS A 1 58  ? 145.611 158.418 155.303 1.00 148.02 ? 53  CYS R CA  1 
ATOM   373  C C   . CYS A 1 58  ? 145.068 157.909 156.634 1.00 148.21 ? 53  CYS R C   1 
ATOM   374  O O   . CYS A 1 58  ? 145.470 158.389 157.700 1.00 145.50 ? 53  CYS R O   1 
ATOM   375  C CB  . CYS A 1 58  ? 144.592 159.332 154.620 1.00 147.79 ? 53  CYS R CB  1 
ATOM   376  S SG  . CYS A 1 58  ? 145.274 160.341 153.284 1.00 149.69 ? 53  CYS R SG  1 
ATOM   377  N N   . PHE A 1 59  ? 144.156 156.935 156.599 1.00 149.39 ? 54  PHE R N   1 
ATOM   378  C CA  . PHE A 1 59  ? 143.401 156.573 157.791 1.00 147.61 ? 54  PHE R CA  1 
ATOM   379  C C   . PHE A 1 59  ? 143.647 155.160 158.302 1.00 145.83 ? 54  PHE R C   1 
ATOM   380  O O   . PHE A 1 59  ? 142.949 154.729 159.227 1.00 145.88 ? 54  PHE R O   1 
ATOM   381  C CB  . PHE A 1 59  ? 141.898 156.759 157.539 1.00 147.82 ? 54  PHE R CB  1 
ATOM   382  C CG  . PHE A 1 59  ? 141.502 158.182 157.268 1.00 148.88 ? 54  PHE R CG  1 
ATOM   383  C CD1 . PHE A 1 59  ? 141.519 159.124 158.282 1.00 147.52 ? 54  PHE R CD1 1 
ATOM   384  C CD2 . PHE A 1 59  ? 141.115 158.578 155.999 1.00 148.57 ? 54  PHE R CD2 1 
ATOM   385  C CE1 . PHE A 1 59  ? 141.155 160.435 158.037 1.00 147.94 ? 54  PHE R CE1 1 
ATOM   386  C CE2 . PHE A 1 59  ? 140.750 159.887 155.746 1.00 147.36 ? 54  PHE R CE2 1 
ATOM   387  C CZ  . PHE A 1 59  ? 140.770 160.817 156.767 1.00 148.09 ? 54  PHE R CZ  1 
ATOM   388  N N   . HIS A 1 60  ? 144.605 154.422 157.742 1.00 147.31 ? 55  HIS R N   1 
ATOM   389  C CA  . HIS A 1 60  ? 144.862 153.055 158.181 1.00 148.85 ? 55  HIS R CA  1 
ATOM   390  C C   . HIS A 1 60  ? 146.334 152.783 158.465 1.00 148.70 ? 55  HIS R C   1 
ATOM   391  O O   . HIS A 1 60  ? 146.723 151.614 158.581 1.00 147.07 ? 55  HIS R O   1 
ATOM   392  C CB  . HIS A 1 60  ? 144.334 152.056 157.148 1.00 147.70 ? 55  HIS R CB  1 
ATOM   393  C CG  . HIS A 1 60  ? 142.871 151.772 157.278 1.00 146.77 ? 55  HIS R CG  1 
ATOM   394  N ND1 . HIS A 1 60  ? 142.339 151.085 158.348 1.00 146.42 ? 55  HIS R ND1 1 
ATOM   395  C CD2 . HIS A 1 60  ? 141.827 152.085 156.475 1.00 146.96 ? 55  HIS R CD2 1 
ATOM   396  C CE1 . HIS A 1 60  ? 141.030 150.986 158.197 1.00 147.31 ? 55  HIS R CE1 1 
ATOM   397  N NE2 . HIS A 1 60  ? 140.694 151.584 157.069 1.00 147.84 ? 55  HIS R NE2 1 
ATOM   398  N N   . LEU A 1 61  ? 147.161 153.817 158.581 1.00 144.27 ? 56  LEU R N   1 
ATOM   399  C CA  . LEU A 1 61  ? 148.576 153.663 158.895 1.00 143.06 ? 56  LEU R CA  1 
ATOM   400  C C   . LEU A 1 61  ? 148.853 154.300 160.249 1.00 142.42 ? 56  LEU R C   1 
ATOM   401  O O   . LEU A 1 61  ? 148.654 155.507 160.423 1.00 141.48 ? 56  LEU R O   1 
ATOM   402  C CB  . LEU A 1 61  ? 149.450 154.294 157.811 1.00 142.98 ? 56  LEU R CB  1 
ATOM   403  C CG  . LEU A 1 61  ? 149.400 153.636 156.431 1.00 142.53 ? 56  LEU R CG  1 
ATOM   404  C CD1 . LEU A 1 61  ? 150.631 154.004 155.617 1.00 141.86 ? 56  LEU R CD1 1 
ATOM   405  C CD2 . LEU A 1 61  ? 149.266 152.125 156.554 1.00 142.37 ? 56  LEU R CD2 1 
ATOM   406  N N   . LYS A 1 62  ? 149.310 153.488 161.204 1.00 150.54 ? 57  LYS R N   1 
ATOM   407  C CA  . LYS A 1 62  ? 149.616 154.002 162.534 1.00 150.33 ? 57  LYS R CA  1 
ATOM   408  C C   . LYS A 1 62  ? 150.914 154.799 162.544 1.00 149.80 ? 57  LYS R C   1 
ATOM   409  O O   . LYS A 1 62  ? 150.995 155.850 163.190 1.00 148.14 ? 57  LYS R O   1 
ATOM   410  C CB  . LYS A 1 62  ? 149.689 152.850 163.538 1.00 150.62 ? 57  LYS R CB  1 
ATOM   411  N N   . SER A 1 63  ? 151.934 154.320 161.836 1.00 147.75 ? 58  SER R N   1 
ATOM   412  C CA  . SER A 1 63  ? 153.226 154.983 161.774 1.00 147.26 ? 58  SER R CA  1 
ATOM   413  C C   . SER A 1 63  ? 153.620 155.191 160.320 1.00 145.84 ? 58  SER R C   1 
ATOM   414  O O   . SER A 1 63  ? 153.186 154.454 159.431 1.00 143.38 ? 58  SER R O   1 
ATOM   415  C CB  . SER A 1 63  ? 154.311 154.175 162.501 1.00 146.26 ? 58  SER R CB  1 
ATOM   416  O OG  . SER A 1 63  ? 154.358 152.842 162.025 1.00 145.68 ? 58  SER R OG  1 
ATOM   417  N N   . TRP A 1 64  ? 154.447 156.207 160.086 1.00 137.13 ? 59  TRP R N   1 
ATOM   418  C CA  . TRP A 1 64  ? 154.880 156.578 158.743 1.00 136.27 ? 59  TRP R CA  1 
ATOM   419  C C   . TRP A 1 64  ? 156.394 156.435 158.652 1.00 134.36 ? 59  TRP R C   1 
ATOM   420  O O   . TRP A 1 64  ? 157.136 157.267 159.185 1.00 130.43 ? 59  TRP R O   1 
ATOM   421  C CB  . TRP A 1 64  ? 154.441 158.000 158.399 1.00 136.23 ? 59  TRP R CB  1 
ATOM   422  C CG  . TRP A 1 64  ? 153.063 158.072 157.819 1.00 135.91 ? 59  TRP R CG  1 
ATOM   423  C CD1 . TRP A 1 64  ? 151.895 158.248 158.500 1.00 135.43 ? 59  TRP R CD1 1 
ATOM   424  C CD2 . TRP A 1 64  ? 152.708 157.958 156.436 1.00 136.76 ? 59  TRP R CD2 1 
ATOM   425  N NE1 . TRP A 1 64  ? 150.835 158.257 157.627 1.00 135.99 ? 59  TRP R NE1 1 
ATOM   426  C CE2 . TRP A 1 64  ? 151.307 158.080 156.354 1.00 136.51 ? 59  TRP R CE2 1 
ATOM   427  C CE3 . TRP A 1 64  ? 153.439 157.767 155.260 1.00 136.67 ? 59  TRP R CE3 1 
ATOM   428  C CZ2 . TRP A 1 64  ? 150.623 158.018 155.142 1.00 135.82 ? 59  TRP R CZ2 1 
ATOM   429  C CZ3 . TRP A 1 64  ? 152.758 157.705 154.058 1.00 136.47 ? 59  TRP R CZ3 1 
ATOM   430  C CH2 . TRP A 1 64  ? 151.364 157.830 154.008 1.00 135.75 ? 59  TRP R CH2 1 
ATOM   431  N N   . LYS A 1 65  ? 156.844 155.378 157.982 1.00 122.18 ? 60  LYS R N   1 
ATOM   432  C CA  . LYS A 1 65  ? 158.251 155.166 157.695 1.00 118.82 ? 60  LYS R CA  1 
ATOM   433  C C   . LYS A 1 65  ? 158.610 155.821 156.361 1.00 120.58 ? 60  LYS R C   1 
ATOM   434  O O   . LYS A 1 65  ? 157.775 156.440 155.698 1.00 123.55 ? 60  LYS R O   1 
ATOM   435  C CB  . LYS A 1 65  ? 158.565 153.672 157.697 1.00 119.00 ? 60  LYS R CB  1 
ATOM   436  C CG  . LYS A 1 65  ? 157.451 152.812 157.124 1.00 122.28 ? 60  LYS R CG  1 
ATOM   437  C CD  . LYS A 1 65  ? 157.233 151.563 157.960 1.00 120.91 ? 60  LYS R CD  1 
ATOM   438  C CE  . LYS A 1 65  ? 156.150 150.679 157.362 1.00 119.66 ? 60  LYS R CE  1 
ATOM   439  N NZ  . LYS A 1 65  ? 154.854 151.396 157.229 1.00 117.06 ? 60  LYS R NZ  1 
ATOM   440  N N   . SER A 1 66  ? 159.876 155.686 155.959 1.00 107.65 ? 61  SER R N   1 
ATOM   441  C CA  . SER A 1 66  ? 160.340 156.354 154.746 1.00 111.82 ? 61  SER R CA  1 
ATOM   442  C C   . SER A 1 66  ? 159.725 155.740 153.492 1.00 113.17 ? 61  SER R C   1 
ATOM   443  O O   . SER A 1 66  ? 159.310 156.464 152.575 1.00 115.62 ? 61  SER R O   1 
ATOM   444  C CB  . SER A 1 66  ? 161.866 156.306 154.678 1.00 110.36 ? 61  SER R CB  1 
ATOM   445  O OG  . SER A 1 66  ? 162.358 157.139 153.644 1.00 114.69 ? 61  SER R OG  1 
ATOM   446  N N   . SER A 1 67  ? 159.658 154.408 153.432 1.00 109.85 ? 62  SER R N   1 
ATOM   447  C CA  . SER A 1 67  ? 159.154 153.741 152.236 1.00 112.43 ? 62  SER R CA  1 
ATOM   448  C C   . SER A 1 67  ? 157.688 154.071 151.991 1.00 114.96 ? 62  SER R C   1 
ATOM   449  O O   . SER A 1 67  ? 157.266 154.243 150.840 1.00 118.35 ? 62  SER R O   1 
ATOM   450  C CB  . SER A 1 67  ? 159.351 152.230 152.356 1.00 112.03 ? 62  SER R CB  1 
ATOM   451  O OG  . SER A 1 67  ? 160.727 151.897 152.389 1.00 111.68 ? 62  SER R OG  1 
ATOM   452  N N   . ARG A 1 68  ? 156.911 154.125 153.075 1.00 114.22 ? 63  ARG R N   1 
ATOM   453  C CA  . ARG A 1 68  ? 155.475 154.489 152.954 1.00 115.94 ? 63  ARG R CA  1 
ATOM   454  C C   . ARG A 1 68  ? 155.356 155.887 152.340 1.00 119.16 ? 63  ARG R C   1 
ATOM   455  O O   . ARG A 1 68  ? 154.538 156.054 151.416 1.00 120.53 ? 63  ARG R O   1 
ATOM   456  C CB  . ARG A 1 68  ? 154.807 154.468 154.327 1.00 115.49 ? 63  ARG R CB  1 
ATOM   457  C CG  . ARG A 1 68  ? 154.796 153.099 154.988 1.00 117.82 ? 63  ARG R CG  1 
ATOM   458  C CD  . ARG A 1 68  ? 153.931 152.117 154.223 1.00 120.74 ? 63  ARG R CD  1 
ATOM   459  N NE  . ARG A 1 68  ? 153.900 150.812 154.866 1.00 122.76 ? 63  ARG R NE  1 
ATOM   460  C CZ  . ARG A 1 68  ? 153.417 149.709 154.306 1.00 121.00 ? 63  ARG R CZ  1 
ATOM   461  N NH1 . ARG A 1 68  ? 153.305 149.627 152.993 1.00 119.55 ? 63  ARG R NH1 1 
ATOM   462  N NH2 . ARG A 1 68  ? 153.050 148.690 155.064 1.00 119.20 ? 63  ARG R NH2 1 
ATOM   463  N N   . ILE A 1 69  ? 156.146 156.846 152.828 1.00 110.60 ? 64  ILE R N   1 
ATOM   464  C CA  . ILE A 1 69  ? 156.121 158.203 152.283 1.00 109.11 ? 64  ILE R CA  1 
ATOM   465  C C   . ILE A 1 69  ? 156.478 158.194 150.800 1.00 111.60 ? 64  ILE R C   1 
ATOM   466  O O   . ILE A 1 69  ? 155.831 158.864 149.977 1.00 115.39 ? 64  ILE R O   1 
ATOM   467  C CB  . ILE A 1 69  ? 157.072 159.110 153.087 1.00 104.57 ? 64  ILE R CB  1 
ATOM   468  C CG1 . ILE A 1 69  ? 156.524 159.338 154.498 1.00 107.65 ? 64  ILE R CG1 1 
ATOM   469  C CG2 . ILE A 1 69  ? 157.309 160.425 152.356 1.00 106.71 ? 64  ILE R CG2 1 
ATOM   470  C CD1 . ILE A 1 69  ? 156.972 160.636 155.140 1.00 108.83 ? 64  ILE R CD1 1 
ATOM   471  N N   . PHE A 1 70  ? 157.520 157.439 150.438 1.00 88.84  ? 65  PHE R N   1 
ATOM   472  C CA  . PHE A 1 70  ? 157.955 157.398 149.047 1.00 79.43  ? 65  PHE R CA  1 
ATOM   473  C C   . PHE A 1 70  ? 156.889 156.797 148.140 1.00 78.30  ? 65  PHE R C   1 
ATOM   474  O O   . PHE A 1 70  ? 156.732 157.237 146.996 1.00 88.36  ? 65  PHE R O   1 
ATOM   475  C CB  . PHE A 1 70  ? 159.263 156.620 148.936 1.00 78.53  ? 65  PHE R CB  1 
ATOM   476  C CG  . PHE A 1 70  ? 160.475 157.422 149.310 1.00 82.04  ? 65  PHE R CG  1 
ATOM   477  C CD1 . PHE A 1 70  ? 160.377 158.781 149.536 1.00 84.04  ? 65  PHE R CD1 1 
ATOM   478  C CD2 . PHE A 1 70  ? 161.709 156.815 149.448 1.00 84.58  ? 65  PHE R CD2 1 
ATOM   479  C CE1 . PHE A 1 70  ? 161.489 159.521 149.884 1.00 86.45  ? 65  PHE R CE1 1 
ATOM   480  C CE2 . PHE A 1 70  ? 162.824 157.550 149.796 1.00 83.08  ? 65  PHE R CE2 1 
ATOM   481  C CZ  . PHE A 1 70  ? 162.714 158.903 150.014 1.00 83.77  ? 65  PHE R CZ  1 
ATOM   482  N N   . LEU A 1 71  ? 156.148 155.801 148.625 1.00 85.59  ? 66  LEU R N   1 
ATOM   483  C CA  . LEU A 1 71  ? 155.038 155.258 147.847 1.00 97.20  ? 66  LEU R CA  1 
ATOM   484  C C   . LEU A 1 71  ? 153.833 156.198 147.837 1.00 108.27 ? 66  LEU R C   1 
ATOM   485  O O   . LEU A 1 71  ? 153.103 156.263 146.837 1.00 111.36 ? 66  LEU R O   1 
ATOM   486  C CB  . LEU A 1 71  ? 154.645 153.883 148.394 1.00 97.35  ? 66  LEU R CB  1 
ATOM   487  C CG  . LEU A 1 71  ? 153.350 153.229 147.907 1.00 100.12 ? 66  LEU R CG  1 
ATOM   488  C CD1 . LEU A 1 71  ? 153.356 153.061 146.398 1.00 98.34  ? 66  LEU R CD1 1 
ATOM   489  C CD2 . LEU A 1 71  ? 153.156 151.885 148.590 1.00 101.71 ? 66  LEU R CD2 1 
ATOM   490  N N   . PHE A 1 72  ? 153.620 156.936 148.929 1.00 119.65 ? 67  PHE R N   1 
ATOM   491  C CA  . PHE A 1 72  ? 152.528 157.900 148.997 1.00 116.70 ? 67  PHE R CA  1 
ATOM   492  C C   . PHE A 1 72  ? 152.693 158.988 147.948 1.00 112.03 ? 67  PHE R C   1 
ATOM   493  O O   . PHE A 1 72  ? 151.708 159.450 147.358 1.00 114.10 ? 67  PHE R O   1 
ATOM   494  C CB  . PHE A 1 72  ? 152.476 158.510 150.399 1.00 117.20 ? 67  PHE R CB  1 
ATOM   495  C CG  . PHE A 1 72  ? 151.197 159.231 150.708 1.00 121.90 ? 67  PHE R CG  1 
ATOM   496  C CD1 . PHE A 1 72  ? 149.979 158.725 150.291 1.00 122.90 ? 67  PHE R CD1 1 
ATOM   497  C CD2 . PHE A 1 72  ? 151.215 160.417 151.422 1.00 120.82 ? 67  PHE R CD2 1 
ATOM   498  C CE1 . PHE A 1 72  ? 148.803 159.389 150.581 1.00 120.91 ? 67  PHE R CE1 1 
ATOM   499  C CE2 . PHE A 1 72  ? 150.043 161.087 151.714 1.00 118.73 ? 67  PHE R CE2 1 
ATOM   500  C CZ  . PHE A 1 72  ? 148.835 160.572 151.292 1.00 118.68 ? 67  PHE R CZ  1 
ATOM   501  N N   . ASN A 1 73  ? 153.930 159.426 147.719 1.00 87.26  ? 68  ASN R N   1 
ATOM   502  C CA  . ASN A 1 73  ? 154.166 160.440 146.694 1.00 88.59  ? 68  ASN R CA  1 
ATOM   503  C C   . ASN A 1 73  ? 153.756 159.942 145.308 1.00 90.72  ? 68  ASN R C   1 
ATOM   504  O O   . ASN A 1 73  ? 153.112 160.672 144.537 1.00 98.91  ? 68  ASN R O   1 
ATOM   505  C CB  . ASN A 1 73  ? 155.633 160.857 146.704 1.00 89.99  ? 68  ASN R CB  1 
ATOM   506  C CG  . ASN A 1 73  ? 155.946 161.853 147.798 1.00 89.12  ? 68  ASN R CG  1 
ATOM   507  O OD1 . ASN A 1 73  ? 156.514 162.911 147.541 1.00 87.10  ? 68  ASN R OD1 1 
ATOM   508  N ND2 . ASN A 1 73  ? 155.576 161.519 149.027 1.00 89.24  ? 68  ASN R ND2 1 
ATOM   509  N N   . LEU A 1 74  ? 154.122 158.703 144.973 1.00 87.96  ? 69  LEU R N   1 
ATOM   510  C CA  . LEU A 1 74  ? 153.718 158.130 143.693 1.00 91.03  ? 69  LEU R CA  1 
ATOM   511  C C   . LEU A 1 74  ? 152.203 158.001 143.608 1.00 99.08  ? 69  LEU R C   1 
ATOM   512  O O   . LEU A 1 74  ? 151.607 158.239 142.547 1.00 104.00 ? 69  LEU R O   1 
ATOM   513  C CB  . LEU A 1 74  ? 154.390 156.771 143.494 1.00 87.89  ? 69  LEU R CB  1 
ATOM   514  C CG  . LEU A 1 74  ? 153.719 155.746 142.580 1.00 89.56  ? 69  LEU R CG  1 
ATOM   515  C CD1 . LEU A 1 74  ? 153.738 156.202 141.130 1.00 94.30  ? 69  LEU R CD1 1 
ATOM   516  C CD2 . LEU A 1 74  ? 154.394 154.397 142.723 1.00 91.37  ? 69  LEU R CD2 1 
ATOM   517  N N   . ALA A 1 75  ? 151.564 157.622 144.717 1.00 110.59 ? 70  ALA R N   1 
ATOM   518  C CA  . ALA A 1 75  ? 150.106 157.557 144.738 1.00 113.57 ? 70  ALA R CA  1 
ATOM   519  C C   . ALA A 1 75  ? 149.492 158.922 144.449 1.00 114.01 ? 70  ALA R C   1 
ATOM   520  O O   . ALA A 1 75  ? 148.504 159.025 143.713 1.00 110.81 ? 70  ALA R O   1 
ATOM   521  C CB  . ALA A 1 75  ? 149.623 157.023 146.086 1.00 111.96 ? 70  ALA R CB  1 
ATOM   522  N N   . VAL A 1 76  ? 150.070 159.982 145.018 1.00 111.23 ? 71  VAL R N   1 
ATOM   523  C CA  . VAL A 1 76  ? 149.566 161.335 144.784 1.00 107.92 ? 71  VAL R CA  1 
ATOM   524  C C   . VAL A 1 76  ? 149.703 161.713 143.314 1.00 109.42 ? 71  VAL R C   1 
ATOM   525  O O   . VAL A 1 76  ? 148.782 162.285 142.713 1.00 116.39 ? 71  VAL R O   1 
ATOM   526  C CB  . VAL A 1 76  ? 150.294 162.338 145.698 1.00 108.30 ? 71  VAL R CB  1 
ATOM   527  C CG1 . VAL A 1 76  ? 150.127 163.757 145.181 1.00 108.52 ? 71  VAL R CG1 1 
ATOM   528  C CG2 . VAL A 1 76  ? 149.783 162.221 147.126 1.00 108.77 ? 71  VAL R CG2 1 
ATOM   529  N N   . ALA A 1 77  ? 150.858 161.411 142.714 1.00 98.40  ? 72  ALA R N   1 
ATOM   530  C CA  . ALA A 1 77  ? 151.048 161.723 141.297 1.00 97.58  ? 72  ALA R CA  1 
ATOM   531  C C   . ALA A 1 77  ? 150.038 160.981 140.423 1.00 102.08 ? 72  ALA R C   1 
ATOM   532  O O   . ALA A 1 77  ? 149.442 161.565 139.502 1.00 109.26 ? 72  ALA R O   1 
ATOM   533  C CB  . ALA A 1 77  ? 152.475 161.386 140.871 1.00 96.64  ? 72  ALA R CB  1 
ATOM   534  N N   . ASP A 1 78  ? 149.821 159.694 140.705 1.00 106.30 ? 73  ASP R N   1 
ATOM   535  C CA  . ASP A 1 78  ? 148.845 158.929 139.935 1.00 111.06 ? 73  ASP R CA  1 
ATOM   536  C C   . ASP A 1 78  ? 147.439 159.488 140.115 1.00 113.45 ? 73  ASP R C   1 
ATOM   537  O O   . ASP A 1 78  ? 146.649 159.529 139.160 1.00 113.10 ? 73  ASP R O   1 
ATOM   538  C CB  . ASP A 1 78  ? 148.894 157.459 140.342 1.00 114.33 ? 73  ASP R CB  1 
ATOM   539  C CG  . ASP A 1 78  ? 150.026 156.712 139.674 1.00 115.31 ? 73  ASP R CG  1 
ATOM   540  O OD1 . ASP A 1 78  ? 150.408 157.094 138.548 1.00 112.77 ? 73  ASP R OD1 1 
ATOM   541  O OD2 . ASP A 1 78  ? 150.538 155.748 140.278 1.00 114.50 ? 73  ASP R OD2 1 
ATOM   542  N N   . PHE A 1 79  ? 147.107 159.911 141.339 1.00 118.55 ? 74  PHE R N   1 
ATOM   543  C CA  . PHE A 1 79  ? 145.807 160.522 141.588 1.00 119.32 ? 74  PHE R CA  1 
ATOM   544  C C   . PHE A 1 79  ? 145.632 161.788 140.763 1.00 116.68 ? 74  PHE R C   1 
ATOM   545  O O   . PHE A 1 79  ? 144.556 162.034 140.206 1.00 118.37 ? 74  PHE R O   1 
ATOM   546  C CB  . PHE A 1 79  ? 145.643 160.825 143.076 1.00 121.55 ? 74  PHE R CB  1 
ATOM   547  C CG  . PHE A 1 79  ? 144.232 161.148 143.477 1.00 124.23 ? 74  PHE R CG  1 
ATOM   548  C CD1 . PHE A 1 79  ? 143.191 160.299 143.143 1.00 122.46 ? 74  PHE R CD1 1 
ATOM   549  C CD2 . PHE A 1 79  ? 143.948 162.299 144.193 1.00 122.24 ? 74  PHE R CD2 1 
ATOM   550  C CE1 . PHE A 1 79  ? 141.893 160.592 143.512 1.00 121.32 ? 74  PHE R CE1 1 
ATOM   551  C CE2 . PHE A 1 79  ? 142.651 162.597 144.567 1.00 120.92 ? 74  PHE R CE2 1 
ATOM   552  C CZ  . PHE A 1 79  ? 141.622 161.743 144.224 1.00 121.79 ? 74  PHE R CZ  1 
ATOM   553  N N   . LEU A 1 80  ? 146.684 162.602 140.671 1.00 105.13 ? 75  LEU R N   1 
ATOM   554  C CA  . LEU A 1 80  ? 146.609 163.789 139.826 1.00 104.21 ? 75  LEU R CA  1 
ATOM   555  C C   . LEU A 1 80  ? 146.362 163.410 138.371 1.00 106.29 ? 75  LEU R C   1 
ATOM   556  O O   . LEU A 1 80  ? 145.571 164.062 137.676 1.00 110.87 ? 75  LEU R O   1 
ATOM   557  C CB  . LEU A 1 80  ? 147.888 164.614 139.958 1.00 103.79 ? 75  LEU R CB  1 
ATOM   558  C CG  . LEU A 1 80  ? 147.843 165.794 140.931 1.00 105.60 ? 75  LEU R CG  1 
ATOM   559  C CD1 . LEU A 1 80  ? 147.197 165.395 142.248 1.00 105.79 ? 75  LEU R CD1 1 
ATOM   560  C CD2 . LEU A 1 80  ? 149.238 166.349 141.162 1.00 107.34 ? 75  LEU R CD2 1 
ATOM   561  N N   . LEU A 1 81  ? 147.019 162.350 137.894 1.00 103.32 ? 76  LEU R N   1 
ATOM   562  C CA  . LEU A 1 81  ? 146.819 161.937 136.504 1.00 103.51 ? 76  LEU R CA  1 
ATOM   563  C C   . LEU A 1 81  ? 145.373 161.533 136.243 1.00 106.35 ? 76  LEU R C   1 
ATOM   564  O O   . LEU A 1 81  ? 144.771 161.937 135.235 1.00 108.52 ? 76  LEU R O   1 
ATOM   565  C CB  . LEU A 1 81  ? 147.742 160.778 136.149 1.00 107.13 ? 76  LEU R CB  1 
ATOM   566  C CG  . LEU A 1 81  ? 147.403 160.189 134.777 1.00 107.95 ? 76  LEU R CG  1 
ATOM   567  C CD1 . LEU A 1 81  ? 147.726 161.185 133.681 1.00 104.44 ? 76  LEU R CD1 1 
ATOM   568  C CD2 . LEU A 1 81  ? 148.116 158.876 134.531 1.00 107.38 ? 76  LEU R CD2 1 
ATOM   569  N N   . ILE A 1 82  ? 144.811 160.695 137.118 1.00 110.40 ? 77  ILE R N   1 
ATOM   570  C CA  . ILE A 1 82  ? 143.432 160.271 136.897 1.00 111.65 ? 77  ILE R CA  1 
ATOM   571  C C   . ILE A 1 82  ? 142.467 161.434 137.076 1.00 113.81 ? 77  ILE R C   1 
ATOM   572  O O   . ILE A 1 82  ? 141.389 161.440 136.471 1.00 108.99 ? 77  ILE R O   1 
ATOM   573  C CB  . ILE A 1 82  ? 143.035 159.097 137.809 1.00 113.81 ? 77  ILE R CB  1 
ATOM   574  C CG1 . ILE A 1 82  ? 143.659 159.261 139.185 1.00 112.74 ? 77  ILE R CG1 1 
ATOM   575  C CG2 . ILE A 1 82  ? 143.457 157.776 137.184 1.00 113.02 ? 77  ILE R CG2 1 
ATOM   576  C CD1 . ILE A 1 82  ? 143.126 158.325 140.220 1.00 111.36 ? 77  ILE R CD1 1 
ATOM   577  N N   . ILE A 1 83  ? 142.832 162.428 137.889 1.00 121.63 ? 78  ILE R N   1 
ATOM   578  C CA  . ILE A 1 83  ? 142.011 163.628 138.008 1.00 118.25 ? 78  ILE R CA  1 
ATOM   579  C C   . ILE A 1 83  ? 142.014 164.408 136.701 1.00 119.41 ? 78  ILE R C   1 
ATOM   580  O O   . ILE A 1 83  ? 140.986 164.961 136.290 1.00 119.41 ? 78  ILE R O   1 
ATOM   581  C CB  . ILE A 1 83  ? 142.507 164.491 139.184 1.00 118.58 ? 78  ILE R CB  1 
ATOM   582  C CG1 . ILE A 1 83  ? 141.885 164.023 140.499 1.00 119.05 ? 78  ILE R CG1 1 
ATOM   583  C CG2 . ILE A 1 83  ? 142.209 165.965 138.949 1.00 115.70 ? 78  ILE R CG2 1 
ATOM   584  C CD1 . ILE A 1 83  ? 142.514 164.655 141.719 1.00 117.84 ? 78  ILE R CD1 1 
ATOM   585  N N   . CYS A 1 84  ? 143.162 164.469 136.029 1.00 119.93 ? 79  CYS R N   1 
ATOM   586  C CA  . CYS A 1 84  ? 143.326 165.345 134.875 1.00 116.58 ? 79  CYS R CA  1 
ATOM   587  C C   . CYS A 1 84  ? 143.071 164.673 133.528 1.00 112.41 ? 79  CYS R C   1 
ATOM   588  O O   . CYS A 1 84  ? 143.124 165.355 132.501 1.00 111.47 ? 79  CYS R O   1 
ATOM   589  C CB  . CYS A 1 84  ? 144.728 165.958 134.889 1.00 113.83 ? 79  CYS R CB  1 
ATOM   590  S SG  . CYS A 1 84  ? 145.097 166.818 136.433 1.00 116.43 ? 79  CYS R SG  1 
ATOM   591  N N   . LEU A 1 85  ? 142.807 163.366 133.491 1.00 111.06 ? 80  LEU R N   1 
ATOM   592  C CA  . LEU A 1 85  ? 142.517 162.771 132.180 1.00 112.02 ? 80  LEU R CA  1 
ATOM   593  C C   . LEU A 1 85  ? 141.177 163.151 131.529 1.00 114.32 ? 80  LEU R C   1 
ATOM   594  O O   . LEU A 1 85  ? 141.097 163.139 130.290 1.00 118.43 ? 80  LEU R O   1 
ATOM   595  C CB  . LEU A 1 85  ? 142.567 161.242 132.238 1.00 114.77 ? 80  LEU R CB  1 
ATOM   596  C CG  . LEU A 1 85  ? 141.447 160.499 132.956 1.00 114.93 ? 80  LEU R CG  1 
ATOM   597  C CD1 . LEU A 1 85  ? 140.523 159.905 131.909 1.00 115.71 ? 80  LEU R CD1 1 
ATOM   598  C CD2 . LEU A 1 85  ? 142.009 159.402 133.821 1.00 116.99 ? 80  LEU R CD2 1 
ATOM   599  N N   . PRO A 1 86  ? 140.094 163.437 132.279 1.00 122.78 ? 81  PRO R N   1 
ATOM   600  C CA  . PRO A 1 86  ? 138.787 163.597 131.604 1.00 122.67 ? 81  PRO R CA  1 
ATOM   601  C C   . PRO A 1 86  ? 138.752 164.687 130.547 1.00 118.84 ? 81  PRO R C   1 
ATOM   602  O O   . PRO A 1 86  ? 138.035 164.546 129.547 1.00 118.06 ? 81  PRO R O   1 
ATOM   603  C CB  . PRO A 1 86  ? 137.825 163.890 132.766 1.00 122.75 ? 81  PRO R CB  1 
ATOM   604  C CG  . PRO A 1 86  ? 138.501 163.331 133.956 1.00 124.00 ? 81  PRO R CG  1 
ATOM   605  C CD  . PRO A 1 86  ? 139.939 163.622 133.732 1.00 123.06 ? 81  PRO R CD  1 
ATOM   606  N N   . PHE A 1 87  ? 139.508 165.769 130.726 1.00 118.74 ? 82  PHE R N   1 
ATOM   607  C CA  . PHE A 1 87  ? 139.627 166.748 129.652 1.00 120.74 ? 82  PHE R CA  1 
ATOM   608  C C   . PHE A 1 87  ? 140.224 166.107 128.405 1.00 121.16 ? 82  PHE R C   1 
ATOM   609  O O   . PHE A 1 87  ? 139.774 166.368 127.283 1.00 121.71 ? 82  PHE R O   1 
ATOM   610  C CB  . PHE A 1 87  ? 140.475 167.935 130.109 1.00 123.03 ? 82  PHE R CB  1 
ATOM   611  C CG  . PHE A 1 87  ? 140.102 168.467 131.466 1.00 124.15 ? 82  PHE R CG  1 
ATOM   612  C CD1 . PHE A 1 87  ? 138.781 168.480 131.886 1.00 122.41 ? 82  PHE R CD1 1 
ATOM   613  C CD2 . PHE A 1 87  ? 141.076 168.952 132.322 1.00 122.78 ? 82  PHE R CD2 1 
ATOM   614  C CE1 . PHE A 1 87  ? 138.441 168.967 133.132 1.00 122.17 ? 82  PHE R CE1 1 
ATOM   615  C CE2 . PHE A 1 87  ? 140.742 169.440 133.569 1.00 120.54 ? 82  PHE R CE2 1 
ATOM   616  C CZ  . PHE A 1 87  ? 139.422 169.448 133.974 1.00 121.14 ? 82  PHE R CZ  1 
ATOM   617  N N   . LEU A 1 88  ? 141.231 165.251 128.589 1.00 121.15 ? 83  LEU R N   1 
ATOM   618  C CA  . LEU A 1 88  ? 141.845 164.567 127.456 1.00 121.19 ? 83  LEU R CA  1 
ATOM   619  C C   . LEU A 1 88  ? 140.852 163.651 126.751 1.00 119.16 ? 83  LEU R C   1 
ATOM   620  O O   . LEU A 1 88  ? 140.808 163.612 125.515 1.00 119.06 ? 83  LEU R O   1 
ATOM   621  C CB  . LEU A 1 88  ? 143.064 163.772 127.921 1.00 123.25 ? 83  LEU R CB  1 
ATOM   622  C CG  . LEU A 1 88  ? 143.947 163.181 126.823 1.00 121.74 ? 83  LEU R CG  1 
ATOM   623  C CD1 . LEU A 1 88  ? 144.599 164.292 126.026 1.00 119.61 ? 83  LEU R CD1 1 
ATOM   624  C CD2 . LEU A 1 88  ? 144.995 162.249 127.412 1.00 120.01 ? 83  LEU R CD2 1 
ATOM   625  N N   . MET A 1 89  ? 140.051 162.896 127.511 1.00 112.49 ? 84  MET R N   1 
ATOM   626  C CA  . MET A 1 89  ? 139.112 161.994 126.845 1.00 111.25 ? 84  MET R CA  1 
ATOM   627  C C   . MET A 1 89  ? 138.013 162.776 126.138 1.00 114.66 ? 84  MET R C   1 
ATOM   628  O O   . MET A 1 89  ? 137.571 162.388 125.049 1.00 115.25 ? 84  MET R O   1 
ATOM   629  C CB  . MET A 1 89  ? 138.508 160.984 127.823 1.00 110.83 ? 84  MET R CB  1 
ATOM   630  C CG  . MET A 1 89  ? 137.601 161.555 128.877 1.00 111.66 ? 84  MET R CG  1 
ATOM   631  S SD  . MET A 1 89  ? 136.811 160.269 129.862 1.00 119.22 ? 84  MET R SD  1 
ATOM   632  C CE  . MET A 1 89  ? 135.521 159.726 128.746 1.00 116.94 ? 84  MET R CE  1 
ATOM   633  N N   . ASP A 1 90  ? 137.567 163.888 126.731 1.00 122.38 ? 85  ASP R N   1 
ATOM   634  C CA  . ASP A 1 90  ? 136.595 164.739 126.052 1.00 122.28 ? 85  ASP R CA  1 
ATOM   635  C C   . ASP A 1 90  ? 137.165 165.291 124.753 1.00 120.95 ? 85  ASP R C   1 
ATOM   636  O O   . ASP A 1 90  ? 136.465 165.351 123.735 1.00 119.52 ? 85  ASP R O   1 
ATOM   637  C CB  . ASP A 1 90  ? 136.157 165.880 126.970 1.00 121.29 ? 85  ASP R CB  1 
ATOM   638  C CG  . ASP A 1 90  ? 135.076 166.741 126.349 1.00 120.81 ? 85  ASP R CG  1 
ATOM   639  O OD1 . ASP A 1 90  ? 133.881 166.447 126.565 1.00 121.80 ? 85  ASP R OD1 1 
ATOM   640  O OD2 . ASP A 1 90  ? 135.420 167.708 125.638 1.00 121.29 ? 85  ASP R OD2 1 
ATOM   641  N N   . ASN A 1 91  ? 138.435 165.707 124.769 1.00 114.41 ? 86  ASN R N   1 
ATOM   642  C CA  . ASN A 1 91  ? 139.077 166.170 123.542 1.00 110.35 ? 86  ASN R CA  1 
ATOM   643  C C   . ASN A 1 91  ? 139.140 165.064 122.500 1.00 105.32 ? 86  ASN R C   1 
ATOM   644  O O   . ASN A 1 91  ? 138.878 165.300 121.316 1.00 105.88 ? 86  ASN R O   1 
ATOM   645  C CB  . ASN A 1 91  ? 140.482 166.684 123.843 1.00 110.15 ? 86  ASN R CB  1 
ATOM   646  C CG  . ASN A 1 91  ? 141.251 167.036 122.587 1.00 110.47 ? 86  ASN R CG  1 
ATOM   647  O OD1 . ASN A 1 91  ? 140.873 167.946 121.849 1.00 113.86 ? 86  ASN R OD1 1 
ATOM   648  N ND2 . ASN A 1 91  ? 142.332 166.310 122.332 1.00 108.53 ? 86  ASN R ND2 1 
ATOM   649  N N   . TYR A 1 92  ? 139.495 163.849 122.922 1.00 105.60 ? 87  TYR R N   1 
ATOM   650  C CA  . TYR A 1 92  ? 139.585 162.738 121.980 1.00 107.73 ? 87  TYR R CA  1 
ATOM   651  C C   . TYR A 1 92  ? 138.220 162.352 121.429 1.00 103.09 ? 87  TYR R C   1 
ATOM   652  O O   . TYR A 1 92  ? 138.136 161.774 120.339 1.00 101.45 ? 87  TYR R O   1 
ATOM   653  C CB  . TYR A 1 92  ? 140.250 161.534 122.646 1.00 112.03 ? 87  TYR R CB  1 
ATOM   654  C CG  . TYR A 1 92  ? 141.745 161.473 122.432 1.00 108.13 ? 87  TYR R CG  1 
ATOM   655  C CD1 . TYR A 1 92  ? 142.277 160.857 121.309 1.00 106.35 ? 87  TYR R CD1 1 
ATOM   656  C CD2 . TYR A 1 92  ? 142.622 162.033 123.348 1.00 103.28 ? 87  TYR R CD2 1 
ATOM   657  C CE1 . TYR A 1 92  ? 143.637 160.798 121.108 1.00 104.56 ? 87  TYR R CE1 1 
ATOM   658  C CE2 . TYR A 1 92  ? 143.985 161.980 123.154 1.00 103.84 ? 87  TYR R CE2 1 
ATOM   659  C CZ  . TYR A 1 92  ? 144.487 161.362 122.033 1.00 104.58 ? 87  TYR R CZ  1 
ATOM   660  O OH  . TYR A 1 92  ? 145.848 161.305 121.835 1.00 107.39 ? 87  TYR R OH  1 
ATOM   661  N N   . VAL A 1 93  ? 137.146 162.648 122.163 1.00 108.37 ? 88  VAL R N   1 
ATOM   662  C CA  . VAL A 1 93  ? 135.808 162.352 121.661 1.00 112.50 ? 88  VAL R CA  1 
ATOM   663  C C   . VAL A 1 93  ? 135.495 163.192 120.427 1.00 109.93 ? 88  VAL R C   1 
ATOM   664  O O   . VAL A 1 93  ? 134.959 162.685 119.434 1.00 106.86 ? 88  VAL R O   1 
ATOM   665  C CB  . VAL A 1 93  ? 134.762 162.562 122.772 1.00 112.70 ? 88  VAL R CB  1 
ATOM   666  C CG1 . VAL A 1 93  ? 133.365 162.672 122.179 1.00 110.48 ? 88  VAL R CG1 1 
ATOM   667  C CG2 . VAL A 1 93  ? 134.820 161.420 123.774 1.00 109.63 ? 88  VAL R CG2 1 
ATOM   668  N N   . ARG A 1 94  ? 135.837 164.479 120.458 1.00 100.39 ? 89  ARG R N   1 
ATOM   669  C CA  . ARG A 1 94  ? 135.407 165.423 119.437 1.00 95.18  ? 89  ARG R CA  1 
ATOM   670  C C   . ARG A 1 94  ? 136.344 165.481 118.234 1.00 100.15 ? 89  ARG R C   1 
ATOM   671  O O   . ARG A 1 94  ? 136.274 166.444 117.462 1.00 103.92 ? 89  ARG R O   1 
ATOM   672  C CB  . ARG A 1 94  ? 135.257 166.820 120.042 1.00 96.92  ? 89  ARG R CB  1 
ATOM   673  C CG  . ARG A 1 94  ? 134.514 166.854 121.364 1.00 98.98  ? 89  ARG R CG  1 
ATOM   674  C CD  . ARG A 1 94  ? 133.058 167.251 121.168 1.00 102.56 ? 89  ARG R CD  1 
ATOM   675  N NE  . ARG A 1 94  ? 132.908 168.563 120.549 1.00 101.77 ? 89  ARG R NE  1 
ATOM   676  C CZ  . ARG A 1 94  ? 133.203 169.717 121.133 1.00 99.57  ? 89  ARG R CZ  1 
ATOM   677  N NH1 . ARG A 1 94  ? 133.671 169.768 122.370 1.00 95.02  ? 89  ARG R NH1 1 
ATOM   678  N NH2 . ARG A 1 94  ? 133.017 170.848 120.461 1.00 100.53 ? 89  ARG R NH2 1 
ATOM   679  N N   . ARG A 1 95  ? 137.210 164.482 118.058 1.00 95.61  ? 90  ARG R N   1 
ATOM   680  C CA  . ARG A 1 95  ? 138.107 164.408 116.902 1.00 87.46  ? 90  ARG R CA  1 
ATOM   681  C C   . ARG A 1 95  ? 138.975 165.661 116.793 1.00 87.41  ? 90  ARG R C   1 
ATOM   682  O O   . ARG A 1 95  ? 139.002 166.340 115.765 1.00 87.67  ? 90  ARG R O   1 
ATOM   683  C CB  . ARG A 1 95  ? 137.318 164.176 115.612 1.00 86.95  ? 90  ARG R CB  1 
ATOM   684  C CG  . ARG A 1 95  ? 138.058 163.376 114.564 1.00 86.70  ? 90  ARG R CG  1 
ATOM   685  C CD  . ARG A 1 95  ? 137.129 162.975 113.436 1.00 92.39  ? 90  ARG R CD  1 
ATOM   686  N NE  . ARG A 1 95  ? 136.707 164.124 112.645 1.00 91.37  ? 90  ARG R NE  1 
ATOM   687  C CZ  . ARG A 1 95  ? 136.836 164.214 111.329 1.00 93.68  ? 90  ARG R CZ  1 
ATOM   688  N NH1 . ARG A 1 95  ? 137.375 163.236 110.619 1.00 95.11  ? 90  ARG R NH1 1 
ATOM   689  N NH2 . ARG A 1 95  ? 136.413 165.311 110.709 1.00 92.35  ? 90  ARG R NH2 1 
ATOM   690  N N   . TRP A 1 96  ? 139.689 165.964 117.878 1.00 102.39 ? 91  TRP R N   1 
ATOM   691  C CA  . TRP A 1 96  ? 140.530 167.157 117.978 1.00 105.82 ? 91  TRP R CA  1 
ATOM   692  C C   . TRP A 1 96  ? 139.706 168.430 117.769 1.00 106.66 ? 91  TRP R C   1 
ATOM   693  O O   . TRP A 1 96  ? 139.902 169.183 116.813 1.00 109.91 ? 91  TRP R O   1 
ATOM   694  C CB  . TRP A 1 96  ? 141.706 167.095 116.996 1.00 109.64 ? 91  TRP R CB  1 
ATOM   695  C CG  . TRP A 1 96  ? 142.384 165.759 116.902 1.00 110.67 ? 91  TRP R CG  1 
ATOM   696  C CD1 . TRP A 1 96  ? 142.130 164.772 115.995 1.00 107.76 ? 91  TRP R CD1 1 
ATOM   697  C CD2 . TRP A 1 96  ? 143.444 165.273 117.734 1.00 107.76 ? 91  TRP R CD2 1 
ATOM   698  N NE1 . TRP A 1 96  ? 142.959 163.700 116.217 1.00 103.98 ? 91  TRP R NE1 1 
ATOM   699  C CE2 . TRP A 1 96  ? 143.776 163.983 117.279 1.00 102.19 ? 91  TRP R CE2 1 
ATOM   700  C CE3 . TRP A 1 96  ? 144.141 165.803 118.825 1.00 108.65 ? 91  TRP R CE3 1 
ATOM   701  C CZ2 . TRP A 1 96  ? 144.772 163.215 117.874 1.00 103.12 ? 91  TRP R CZ2 1 
ATOM   702  C CZ3 . TRP A 1 96  ? 145.131 165.040 119.414 1.00 108.74 ? 91  TRP R CZ3 1 
ATOM   703  C CH2 . TRP A 1 96  ? 145.437 163.760 118.938 1.00 108.40 ? 91  TRP R CH2 1 
ATOM   704  N N   . ASP A 1 97  ? 138.765 168.656 118.686 1.00 107.87 ? 92  ASP R N   1 
ATOM   705  C CA  . ASP A 1 97  ? 137.951 169.874 118.709 1.00 107.77 ? 92  ASP R CA  1 
ATOM   706  C C   . ASP A 1 97  ? 137.903 170.375 120.150 1.00 103.70 ? 92  ASP R C   1 
ATOM   707  O O   . ASP A 1 97  ? 137.001 170.023 120.914 1.00 105.39 ? 92  ASP R O   1 
ATOM   708  C CB  . ASP A 1 97  ? 136.557 169.618 118.148 1.00 109.92 ? 92  ASP R CB  1 
ATOM   709  C CG  . ASP A 1 97  ? 135.970 170.840 117.472 1.00 110.27 ? 92  ASP R CG  1 
ATOM   710  O OD1 . ASP A 1 97  ? 136.734 171.785 117.185 1.00 108.76 ? 92  ASP R OD1 1 
ATOM   711  O OD2 . ASP A 1 97  ? 134.745 170.855 117.227 1.00 110.69 ? 92  ASP R OD2 1 
ATOM   712  N N   . TRP A 1 98  ? 138.878 171.202 120.513 1.00 97.94  ? 93  TRP R N   1 
ATOM   713  C CA  . TRP A 1 98  ? 138.980 171.733 121.864 1.00 97.96  ? 93  TRP R CA  1 
ATOM   714  C C   . TRP A 1 98  ? 137.924 172.803 122.102 1.00 101.83 ? 93  TRP R C   1 
ATOM   715  O O   . TRP A 1 98  ? 137.608 173.596 121.211 1.00 100.99 ? 93  TRP R O   1 
ATOM   716  C CB  . TRP A 1 98  ? 140.375 172.316 122.090 1.00 98.98  ? 93  TRP R CB  1 
ATOM   717  C CG  . TRP A 1 98  ? 140.750 172.539 123.521 1.00 98.41  ? 93  TRP R CG  1 
ATOM   718  C CD1 . TRP A 1 98  ? 141.036 173.735 124.111 1.00 104.35 ? 93  TRP R CD1 1 
ATOM   719  C CD2 . TRP A 1 98  ? 140.918 171.542 124.536 1.00 92.86  ? 93  TRP R CD2 1 
ATOM   720  N NE1 . TRP A 1 98  ? 141.356 173.548 125.433 1.00 104.04 ? 93  TRP R NE1 1 
ATOM   721  C CE2 . TRP A 1 98  ? 141.292 172.210 125.718 1.00 95.36  ? 93  TRP R CE2 1 
ATOM   722  C CE3 . TRP A 1 98  ? 140.781 170.153 124.561 1.00 91.99  ? 93  TRP R CE3 1 
ATOM   723  C CZ2 . TRP A 1 98  ? 141.529 171.537 126.911 1.00 92.53  ? 93  TRP R CZ2 1 
ATOM   724  C CZ3 . TRP A 1 98  ? 141.016 169.488 125.747 1.00 96.51  ? 93  TRP R CZ3 1 
ATOM   725  C CH2 . TRP A 1 98  ? 141.386 170.179 126.905 1.00 98.87  ? 93  TRP R CH2 1 
ATOM   726  N N   . LYS A 1 99  ? 137.376 172.820 123.318 1.00 108.35 ? 94  LYS R N   1 
ATOM   727  C CA  . LYS A 1 99  ? 136.399 173.824 123.713 1.00 105.70 ? 94  LYS R CA  1 
ATOM   728  C C   . LYS A 1 99  ? 136.642 174.416 125.092 1.00 102.38 ? 94  LYS R C   1 
ATOM   729  O O   . LYS A 1 99  ? 136.036 175.445 125.412 1.00 106.94 ? 94  LYS R O   1 
ATOM   730  C CB  . LYS A 1 99  ? 134.980 173.237 123.676 1.00 102.45 ? 94  LYS R CB  1 
ATOM   731  C CG  . LYS A 1 99  ? 134.403 173.105 122.281 1.00 105.06 ? 94  LYS R CG  1 
ATOM   732  C CD  . LYS A 1 99  ? 134.464 174.424 121.529 1.00 106.02 ? 94  LYS R CD  1 
ATOM   733  C CE  . LYS A 1 99  ? 133.731 174.334 120.200 1.00 105.35 ? 94  LYS R CE  1 
ATOM   734  N NZ  . LYS A 1 99  ? 134.122 175.430 119.271 1.00 105.98 ? 94  LYS R NZ  1 
ATOM   735  N N   . PHE A 1 100 ? 137.504 173.814 125.911 1.00 104.82 ? 95  PHE R N   1 
ATOM   736  C CA  . PHE A 1 100 ? 137.662 174.276 127.285 1.00 109.48 ? 95  PHE R CA  1 
ATOM   737  C C   . PHE A 1 100 ? 138.432 175.589 127.362 1.00 108.21 ? 95  PHE R C   1 
ATOM   738  O O   . PHE A 1 100 ? 138.191 176.388 128.273 1.00 113.82 ? 95  PHE R O   1 
ATOM   739  C CB  . PHE A 1 100 ? 138.349 173.202 128.129 1.00 114.56 ? 95  PHE R CB  1 
ATOM   740  C CG  . PHE A 1 100 ? 137.521 171.961 128.341 1.00 115.15 ? 95  PHE R CG  1 
ATOM   741  C CD1 . PHE A 1 100 ? 137.098 171.189 127.271 1.00 113.69 ? 95  PHE R CD1 1 
ATOM   742  C CD2 . PHE A 1 100 ? 137.168 171.567 129.620 1.00 113.12 ? 95  PHE R CD2 1 
ATOM   743  C CE1 . PHE A 1 100 ? 136.342 170.053 127.472 1.00 115.29 ? 95  PHE R CE1 1 
ATOM   744  C CE2 . PHE A 1 100 ? 136.410 170.431 129.828 1.00 113.24 ? 95  PHE R CE2 1 
ATOM   745  C CZ  . PHE A 1 100 ? 135.997 169.673 128.752 1.00 114.02 ? 95  PHE R CZ  1 
ATOM   746  N N   . GLY A 1 101 ? 139.347 175.834 126.437 1.00 100.43 ? 96  GLY R N   1 
ATOM   747  C CA  . GLY A 1 101 ? 140.066 177.089 126.380 1.00 103.19 ? 96  GLY R CA  1 
ATOM   748  C C   . GLY A 1 101 ? 141.567 176.913 126.541 1.00 111.02 ? 96  GLY R C   1 
ATOM   749  O O   . GLY A 1 101 ? 142.081 175.826 126.808 1.00 116.61 ? 96  GLY R O   1 
ATOM   750  N N   . ASP A 1 102 ? 142.263 178.041 126.371 1.00 118.36 ? 97  ASP R N   1 
ATOM   751  C CA  . ASP A 1 102 ? 143.722 178.046 126.424 1.00 120.13 ? 97  ASP R CA  1 
ATOM   752  C C   . ASP A 1 102 ? 144.233 177.663 127.808 1.00 120.37 ? 97  ASP R C   1 
ATOM   753  O O   . ASP A 1 102 ? 145.211 176.912 127.932 1.00 124.07 ? 97  ASP R O   1 
ATOM   754  C CB  . ASP A 1 102 ? 144.248 179.423 126.017 1.00 115.52 ? 97  ASP R CB  1 
ATOM   755  C CG  . ASP A 1 102 ? 145.720 179.603 126.323 1.00 117.90 ? 97  ASP R CG  1 
ATOM   756  O OD1 . ASP A 1 102 ? 146.053 179.974 127.468 1.00 114.92 ? 97  ASP R OD1 1 
ATOM   757  O OD2 . ASP A 1 102 ? 146.547 179.374 125.416 1.00 121.08 ? 97  ASP R OD2 1 
ATOM   758  N N   . ILE A 1 103 ? 143.602 178.190 128.860 1.00 106.04 ? 98  ILE R N   1 
ATOM   759  C CA  . ILE A 1 103 ? 144.015 177.836 130.218 1.00 109.99 ? 98  ILE R CA  1 
ATOM   760  C C   . ILE A 1 103 ? 143.852 176.347 130.486 1.00 116.44 ? 98  ILE R C   1 
ATOM   761  O O   . ILE A 1 103 ? 144.806 175.724 130.989 1.00 119.27 ? 98  ILE R O   1 
ATOM   762  C CB  . ILE A 1 103 ? 143.272 178.713 131.243 1.00 112.73 ? 98  ILE R CB  1 
ATOM   763  C CG1 . ILE A 1 103 ? 143.008 180.107 130.671 1.00 114.31 ? 98  ILE R CG1 1 
ATOM   764  C CG2 . ILE A 1 103 ? 144.060 178.792 132.543 1.00 111.95 ? 98  ILE R CG2 1 
ATOM   765  C CD1 . ILE A 1 103 ? 142.107 180.961 131.536 1.00 115.54 ? 98  ILE R CD1 1 
ATOM   766  N N   . PRO A 1 104 ? 142.708 175.711 130.200 1.00 121.12 ? 99  PRO R N   1 
ATOM   767  C CA  . PRO A 1 104 ? 142.638 174.251 130.363 1.00 123.05 ? 99  PRO R CA  1 
ATOM   768  C C   . PRO A 1 104 ? 143.590 173.486 129.461 1.00 122.70 ? 99  PRO R C   1 
ATOM   769  O O   . PRO A 1 104 ? 144.084 172.430 129.868 1.00 121.73 ? 99  PRO R O   1 
ATOM   770  C CB  . PRO A 1 104 ? 141.172 173.934 130.043 1.00 119.46 ? 99  PRO R CB  1 
ATOM   771  C CG  . PRO A 1 104 ? 140.453 175.196 130.344 1.00 116.61 ? 99  PRO R CG  1 
ATOM   772  C CD  . PRO A 1 104 ? 141.381 176.267 129.874 1.00 116.08 ? 99  PRO R CD  1 
ATOM   773  N N   . CYS A 1 105 ? 143.867 173.978 128.250 1.00 119.07 ? 100 CYS R N   1 
ATOM   774  C CA  . CYS A 1 105 ? 144.842 173.309 127.389 1.00 117.02 ? 100 CYS R CA  1 
ATOM   775  C C   . CYS A 1 105 ? 146.219 173.270 128.046 1.00 117.98 ? 100 CYS R C   1 
ATOM   776  O O   . CYS A 1 105 ? 146.850 172.204 128.152 1.00 121.20 ? 100 CYS R O   1 
ATOM   777  C CB  . CYS A 1 105 ? 144.905 174.020 126.037 1.00 115.56 ? 100 CYS R CB  1 
ATOM   778  S SG  . CYS A 1 105 ? 146.336 173.616 125.014 1.00 127.89 ? 100 CYS R SG  1 
ATOM   779  N N   . ARG A 1 106 ? 146.693 174.429 128.509 1.00 106.21 ? 101 ARG R N   1 
ATOM   780  C CA  . ARG A 1 106 ? 147.991 174.484 129.174 1.00 107.95 ? 101 ARG R CA  1 
ATOM   781  C C   . ARG A 1 106 ? 147.993 173.649 130.447 1.00 108.94 ? 101 ARG R C   1 
ATOM   782  O O   . ARG A 1 106 ? 148.977 172.957 130.746 1.00 113.57 ? 101 ARG R O   1 
ATOM   783  C CB  . ARG A 1 106 ? 148.361 175.930 129.486 1.00 105.96 ? 101 ARG R CB  1 
ATOM   784  C CG  . ARG A 1 106 ? 148.411 176.828 128.274 1.00 109.04 ? 101 ARG R CG  1 
ATOM   785  C CD  . ARG A 1 106 ? 148.619 178.267 128.691 1.00 113.28 ? 101 ARG R CD  1 
ATOM   786  N NE  . ARG A 1 106 ? 147.407 178.883 129.216 1.00 113.23 ? 101 ARG R NE  1 
ATOM   787  C CZ  . ARG A 1 106 ? 147.390 179.772 130.199 1.00 111.53 ? 101 ARG R CZ  1 
ATOM   788  N NH1 . ARG A 1 106 ? 148.501 180.144 130.815 1.00 113.30 ? 101 ARG R NH1 1 
ATOM   789  N NH2 . ARG A 1 106 ? 146.232 180.302 130.576 1.00 108.06 ? 101 ARG R NH2 1 
ATOM   790  N N   . LEU A 1 107 ? 146.899 173.705 131.212 1.00 97.84  ? 102 LEU R N   1 
ATOM   791  C CA  . LEU A 1 107 ? 146.817 172.917 132.435 1.00 97.47  ? 102 LEU R CA  1 
ATOM   792  C C   . LEU A 1 107 ? 146.909 171.430 132.136 1.00 103.54 ? 102 LEU R C   1 
ATOM   793  O O   . LEU A 1 107 ? 147.612 170.695 132.836 1.00 108.04 ? 102 LEU R O   1 
ATOM   794  C CB  . LEU A 1 107 ? 145.523 173.234 133.181 1.00 99.11  ? 102 LEU R CB  1 
ATOM   795  C CG  . LEU A 1 107 ? 145.604 174.358 134.213 1.00 103.59 ? 102 LEU R CG  1 
ATOM   796  C CD1 . LEU A 1 107 ? 144.224 174.678 134.766 1.00 103.59 ? 102 LEU R CD1 1 
ATOM   797  C CD2 . LEU A 1 107 ? 146.560 173.984 135.332 1.00 104.25 ? 102 LEU R CD2 1 
ATOM   798  N N   . MET A 1 108 ? 146.210 170.966 131.098 1.00 97.47  ? 103 MET R N   1 
ATOM   799  C CA  . MET A 1 108 ? 146.254 169.550 130.755 1.00 98.97  ? 103 MET R CA  1 
ATOM   800  C C   . MET A 1 108 ? 147.658 169.130 130.349 1.00 101.14 ? 103 MET R C   1 
ATOM   801  O O   . MET A 1 108 ? 148.155 168.087 130.796 1.00 104.20 ? 103 MET R O   1 
ATOM   802  C CB  . MET A 1 108 ? 145.251 169.249 129.642 1.00 94.80  ? 103 MET R CB  1 
ATOM   803  C CG  . MET A 1 108 ? 145.360 167.852 129.066 1.00 96.79  ? 103 MET R CG  1 
ATOM   804  S SD  . MET A 1 108 ? 146.140 167.823 127.446 1.00 102.98 ? 103 MET R SD  1 
ATOM   805  C CE  . MET A 1 108 ? 144.975 168.798 126.501 1.00 100.49 ? 103 MET R CE  1 
ATOM   806  N N   . LEU A 1 109 ? 148.325 169.940 129.521 1.00 92.37  ? 104 LEU R N   1 
ATOM   807  C CA  . LEU A 1 109 ? 149.686 169.598 129.113 1.00 87.30  ? 104 LEU R CA  1 
ATOM   808  C C   . LEU A 1 109 ? 150.610 169.491 130.323 1.00 91.91  ? 104 LEU R C   1 
ATOM   809  O O   . LEU A 1 109 ? 151.350 168.504 130.478 1.00 100.98 ? 104 LEU R O   1 
ATOM   810  C CB  . LEU A 1 109 ? 150.216 170.634 128.122 1.00 85.40  ? 104 LEU R CB  1 
ATOM   811  C CG  . LEU A 1 109 ? 149.493 170.726 126.780 1.00 90.09  ? 104 LEU R CG  1 
ATOM   812  C CD1 . LEU A 1 109 ? 150.144 171.772 125.892 1.00 91.39  ? 104 LEU R CD1 1 
ATOM   813  C CD2 . LEU A 1 109 ? 149.482 169.375 126.095 1.00 89.86  ? 104 LEU R CD2 1 
ATOM   814  N N   . PHE A 1 110 ? 150.566 170.496 131.202 1.00 90.59  ? 105 PHE R N   1 
ATOM   815  C CA  . PHE A 1 110 ? 151.470 170.508 132.347 1.00 92.25  ? 105 PHE R CA  1 
ATOM   816  C C   . PHE A 1 110 ? 151.168 169.364 133.305 1.00 94.43  ? 105 PHE R C   1 
ATOM   817  O O   . PHE A 1 110 ? 152.089 168.722 133.823 1.00 100.57 ? 105 PHE R O   1 
ATOM   818  C CB  . PHE A 1 110 ? 151.393 171.853 133.064 1.00 93.61  ? 105 PHE R CB  1 
ATOM   819  C CG  . PHE A 1 110 ? 152.492 172.069 134.061 1.00 91.08  ? 105 PHE R CG  1 
ATOM   820  C CD1 . PHE A 1 110 ? 153.813 172.085 133.657 1.00 90.81  ? 105 PHE R CD1 1 
ATOM   821  C CD2 . PHE A 1 110 ? 152.206 172.287 135.395 1.00 90.51  ? 105 PHE R CD2 1 
ATOM   822  C CE1 . PHE A 1 110 ? 154.822 172.292 134.569 1.00 95.75  ? 105 PHE R CE1 1 
ATOM   823  C CE2 . PHE A 1 110 ? 153.213 172.494 136.311 1.00 94.66  ? 105 PHE R CE2 1 
ATOM   824  C CZ  . PHE A 1 110 ? 154.523 172.498 135.896 1.00 97.41  ? 105 PHE R CZ  1 
ATOM   825  N N   . MET A 1 111 ? 149.884 169.083 133.544 1.00 93.85  ? 106 MET R N   1 
ATOM   826  C CA  . MET A 1 111 ? 149.511 167.982 134.427 1.00 100.00 ? 106 MET R CA  1 
ATOM   827  C C   . MET A 1 111 ? 149.990 166.643 133.882 1.00 104.09 ? 106 MET R C   1 
ATOM   828  O O   . MET A 1 111 ? 150.512 165.809 134.631 1.00 104.68 ? 106 MET R O   1 
ATOM   829  C CB  . MET A 1 111 ? 147.996 167.970 134.635 1.00 99.64  ? 106 MET R CB  1 
ATOM   830  C CG  . MET A 1 111 ? 147.374 169.120 135.456 1.00 101.60 ? 106 MET R CG  1 
ATOM   831  S SD  . MET A 1 111 ? 148.131 169.661 137.013 1.00 108.01 ? 106 MET R SD  1 
ATOM   832  C CE  . MET A 1 111 ? 149.514 170.666 136.490 1.00 96.91  ? 106 MET R CE  1 
ATOM   833  N N   . LEU A 1 112 ? 149.818 166.413 132.576 1.00 91.79  ? 107 LEU R N   1 
ATOM   834  C CA  . LEU A 1 112 ? 150.268 165.152 131.993 1.00 81.48  ? 107 LEU R CA  1 
ATOM   835  C C   . LEU A 1 112 ? 151.776 164.985 132.134 1.00 84.05  ? 107 LEU R C   1 
ATOM   836  O O   . LEU A 1 112 ? 152.258 163.933 132.592 1.00 93.83  ? 107 LEU R O   1 
ATOM   837  C CB  . LEU A 1 112 ? 149.859 165.082 130.523 1.00 82.05  ? 107 LEU R CB  1 
ATOM   838  C CG  . LEU A 1 112 ? 148.558 164.352 130.195 1.00 89.19  ? 107 LEU R CG  1 
ATOM   839  C CD1 . LEU A 1 112 ? 148.642 162.916 130.662 1.00 91.82  ? 107 LEU R CD1 1 
ATOM   840  C CD2 . LEU A 1 112 ? 147.362 165.040 130.823 1.00 91.59  ? 107 LEU R CD2 1 
ATOM   841  N N   . ALA A 1 113 ? 152.539 166.017 131.757 1.00 78.49  ? 108 ALA R N   1 
ATOM   842  C CA  . ALA A 1 113 ? 153.992 165.916 131.852 1.00 80.14  ? 108 ALA R CA  1 
ATOM   843  C C   . ALA A 1 113 ? 154.435 165.707 133.295 1.00 87.84  ? 108 ALA R C   1 
ATOM   844  O O   . ALA A 1 113 ? 155.326 164.889 133.572 1.00 96.55  ? 108 ALA R O   1 
ATOM   845  C CB  . ALA A 1 113 ? 154.646 167.164 131.262 1.00 81.41  ? 108 ALA R CB  1 
ATOM   846  N N   . MET A 1 114 ? 153.815 166.433 134.230 1.00 92.28  ? 109 MET R N   1 
ATOM   847  C CA  . MET A 1 114 ? 154.179 166.315 135.635 1.00 92.96  ? 109 MET R CA  1 
ATOM   848  C C   . MET A 1 114 ? 153.900 164.918 136.162 1.00 92.70  ? 109 MET R C   1 
ATOM   849  O O   . MET A 1 114 ? 154.734 164.328 136.861 1.00 100.17 ? 109 MET R O   1 
ATOM   850  C CB  . MET A 1 114 ? 153.423 167.361 136.457 1.00 98.39  ? 109 MET R CB  1 
ATOM   851  C CG  . MET A 1 114 ? 153.531 167.177 137.963 1.00 98.99  ? 109 MET R CG  1 
ATOM   852  S SD  . MET A 1 114 ? 155.197 167.364 138.640 1.00 110.12 ? 109 MET R SD  1 
ATOM   853  C CE  . MET A 1 114 ? 155.961 168.487 137.474 1.00 96.57  ? 109 MET R CE  1 
ATOM   854  N N   . ASN A 1 115 ? 152.722 164.377 135.847 1.00 79.15  ? 110 ASN R N   1 
ATOM   855  C CA  . ASN A 1 115 ? 152.402 163.015 136.249 1.00 84.49  ? 110 ASN R CA  1 
ATOM   856  C C   . ASN A 1 115 ? 153.455 162.033 135.766 1.00 91.49  ? 110 ASN R C   1 
ATOM   857  O O   . ASN A 1 115 ? 153.970 161.223 136.546 1.00 93.75  ? 110 ASN R O   1 
ATOM   858  C CB  . ASN A 1 115 ? 151.038 162.608 135.705 1.00 85.21  ? 110 ASN R CB  1 
ATOM   859  C CG  . ASN A 1 115 ? 150.898 161.107 135.593 1.00 91.92  ? 110 ASN R CG  1 
ATOM   860  O OD1 . ASN A 1 115 ? 150.790 160.566 134.494 1.00 90.57  ? 110 ASN R OD1 1 
ATOM   861  N ND2 . ASN A 1 115 ? 150.911 160.423 136.731 1.00 93.17  ? 110 ASN R ND2 1 
ATOM   862  N N   . ARG A 1 116 ? 153.776 162.081 134.471 1.00 78.13  ? 111 ARG R N   1 
ATOM   863  C CA  . ARG A 1 116 ? 154.703 161.095 133.924 1.00 68.82  ? 111 ARG R CA  1 
ATOM   864  C C   . ARG A 1 116 ? 156.068 161.199 134.597 1.00 70.09  ? 111 ARG R C   1 
ATOM   865  O O   . ARG A 1 116 ? 156.631 160.192 135.065 1.00 82.68  ? 111 ARG R O   1 
ATOM   866  C CB  . ARG A 1 116 ? 154.820 161.279 132.413 1.00 68.92  ? 111 ARG R CB  1 
ATOM   867  C CG  . ARG A 1 116 ? 153.864 160.417 131.612 1.00 61.71  ? 111 ARG R CG  1 
ATOM   868  C CD  . ARG A 1 116 ? 154.300 160.333 130.166 1.00 67.73  ? 111 ARG R CD  1 
ATOM   869  N NE  . ARG A 1 116 ? 153.722 161.395 129.353 1.00 79.97  ? 111 ARG R NE  1 
ATOM   870  C CZ  . ARG A 1 116 ? 154.385 162.466 128.944 1.00 84.85  ? 111 ARG R CZ  1 
ATOM   871  N NH1 . ARG A 1 116 ? 155.659 162.648 129.248 1.00 80.28  ? 111 ARG R NH1 1 
ATOM   872  N NH2 . ARG A 1 116 ? 153.755 163.377 128.207 1.00 81.64  ? 111 ARG R NH2 1 
ATOM   873  N N   . GLN A 1 117 ? 156.603 162.420 134.682 1.00 59.75  ? 112 GLN R N   1 
ATOM   874  C CA  . GLN A 1 117 ? 157.928 162.603 135.261 1.00 62.60  ? 112 GLN R CA  1 
ATOM   875  C C   . GLN A 1 117 ? 157.965 162.163 136.720 1.00 73.48  ? 112 GLN R C   1 
ATOM   876  O O   . GLN A 1 117 ? 158.892 161.457 137.140 1.00 82.98  ? 112 GLN R O   1 
ATOM   877  C CB  . GLN A 1 117 ? 158.357 164.062 135.130 1.00 66.71  ? 112 GLN R CB  1 
ATOM   878  C CG  . GLN A 1 117 ? 159.834 164.293 135.355 1.00 73.22  ? 112 GLN R CG  1 
ATOM   879  C CD  . GLN A 1 117 ? 160.658 163.958 134.136 1.00 73.45  ? 112 GLN R CD  1 
ATOM   880  O OE1 . GLN A 1 117 ? 160.562 164.626 133.109 1.00 75.90  ? 112 GLN R OE1 1 
ATOM   881  N NE2 . GLN A 1 117 ? 161.478 162.921 134.242 1.00 75.27  ? 112 GLN R NE2 1 
ATOM   882  N N   . GLY A 1 118 ? 156.959 162.556 137.505 1.00 73.73  ? 113 GLY R N   1 
ATOM   883  C CA  . GLY A 1 118 ? 156.953 162.198 138.912 1.00 74.90  ? 113 GLY R CA  1 
ATOM   884  C C   . GLY A 1 118 ? 156.808 160.707 139.137 1.00 74.83  ? 113 GLY R C   1 
ATOM   885  O O   . GLY A 1 118 ? 157.473 160.135 140.009 1.00 82.02  ? 113 GLY R O   1 
ATOM   886  N N   . SER A 1 119 ? 155.942 160.054 138.357 1.00 58.37  ? 114 SER R N   1 
ATOM   887  C CA  . SER A 1 119 ? 155.780 158.612 138.486 1.00 65.97  ? 114 SER R CA  1 
ATOM   888  C C   . SER A 1 119 ? 157.096 157.891 138.225 1.00 70.72  ? 114 SER R C   1 
ATOM   889  O O   . SER A 1 119 ? 157.510 157.021 139.006 1.00 76.31  ? 114 SER R O   1 
ATOM   890  C CB  . SER A 1 119 ? 154.695 158.123 137.529 1.00 64.42  ? 114 SER R CB  1 
ATOM   891  O OG  . SER A 1 119 ? 154.238 156.832 137.888 1.00 72.59  ? 114 SER R OG  1 
ATOM   892  N N   . ILE A 1 120 ? 157.785 158.259 137.141 1.00 55.94  ? 115 ILE R N   1 
ATOM   893  C CA  . ILE A 1 120 ? 159.044 157.586 136.830 1.00 51.98  ? 115 ILE R CA  1 
ATOM   894  C C   . ILE A 1 120 ? 160.085 157.858 137.912 1.00 58.33  ? 115 ILE R C   1 
ATOM   895  O O   . ILE A 1 120 ? 160.805 156.944 138.350 1.00 68.91  ? 115 ILE R O   1 
ATOM   896  C CB  . ILE A 1 120 ? 159.540 157.999 135.434 1.00 51.66  ? 115 ILE R CB  1 
ATOM   897  C CG1 . ILE A 1 120 ? 158.880 157.120 134.374 1.00 49.52  ? 115 ILE R CG1 1 
ATOM   898  C CG2 . ILE A 1 120 ? 161.051 157.896 135.344 1.00 60.80  ? 115 ILE R CG2 1 
ATOM   899  C CD1 . ILE A 1 120 ? 159.376 157.368 132.985 1.00 56.82  ? 115 ILE R CD1 1 
ATOM   900  N N   . ILE A 1 121 ? 160.173 159.109 138.375 1.00 57.48  ? 116 ILE R N   1 
ATOM   901  C CA  . ILE A 1 121 ? 161.182 159.456 139.373 1.00 62.09  ? 116 ILE R CA  1 
ATOM   902  C C   . ILE A 1 121 ? 160.954 158.675 140.662 1.00 70.36  ? 116 ILE R C   1 
ATOM   903  O O   . ILE A 1 121 ? 161.903 158.166 141.274 1.00 78.20  ? 116 ILE R O   1 
ATOM   904  C CB  . ILE A 1 121 ? 161.193 160.976 139.619 1.00 58.64  ? 116 ILE R CB  1 
ATOM   905  C CG1 . ILE A 1 121 ? 162.153 161.662 138.647 1.00 60.76  ? 116 ILE R CG1 1 
ATOM   906  C CG2 . ILE A 1 121 ? 161.591 161.292 141.049 1.00 64.02  ? 116 ILE R CG2 1 
ATOM   907  C CD1 . ILE A 1 121 ? 162.003 163.166 138.600 1.00 68.02  ? 116 ILE R CD1 1 
ATOM   908  N N   . PHE A 1 122 ? 159.697 158.545 141.086 1.00 62.23  ? 117 PHE R N   1 
ATOM   909  C CA  . PHE A 1 122 ? 159.440 157.848 142.339 1.00 61.22  ? 117 PHE R CA  1 
ATOM   910  C C   . PHE A 1 122 ? 159.599 156.337 142.206 1.00 65.60  ? 117 PHE R C   1 
ATOM   911  O O   . PHE A 1 122 ? 160.022 155.681 143.169 1.00 70.63  ? 117 PHE R O   1 
ATOM   912  C CB  . PHE A 1 122 ? 158.060 158.226 142.867 1.00 62.49  ? 117 PHE R CB  1 
ATOM   913  C CG  . PHE A 1 122 ? 158.017 159.600 143.468 1.00 67.59  ? 117 PHE R CG  1 
ATOM   914  C CD1 . PHE A 1 122 ? 158.972 159.988 144.392 1.00 64.58  ? 117 PHE R CD1 1 
ATOM   915  C CD2 . PHE A 1 122 ? 157.048 160.511 143.094 1.00 67.12  ? 117 PHE R CD2 1 
ATOM   916  C CE1 . PHE A 1 122 ? 158.952 161.248 144.941 1.00 60.73  ? 117 PHE R CE1 1 
ATOM   917  C CE2 . PHE A 1 122 ? 157.025 161.775 143.641 1.00 62.45  ? 117 PHE R CE2 1 
ATOM   918  C CZ  . PHE A 1 122 ? 157.979 162.143 144.565 1.00 60.70  ? 117 PHE R CZ  1 
ATOM   919  N N   . LEU A 1 123 ? 159.309 155.768 141.032 1.00 57.53  ? 118 LEU R N   1 
ATOM   920  C CA  . LEU A 1 123 ? 159.671 154.371 140.800 1.00 54.14  ? 118 LEU R CA  1 
ATOM   921  C C   . LEU A 1 123 ? 161.173 154.168 140.968 1.00 53.23  ? 118 LEU R C   1 
ATOM   922  O O   . LEU A 1 123 ? 161.620 153.220 141.631 1.00 59.08  ? 118 LEU R O   1 
ATOM   923  C CB  . LEU A 1 123 ? 159.230 153.929 139.407 1.00 49.22  ? 118 LEU R CB  1 
ATOM   924  C CG  . LEU A 1 123 ? 157.736 153.818 139.124 1.00 56.61  ? 118 LEU R CG  1 
ATOM   925  C CD1 . LEU A 1 123 ? 157.507 153.071 137.823 1.00 55.31  ? 118 LEU R CD1 1 
ATOM   926  C CD2 . LEU A 1 123 ? 157.017 153.137 140.273 1.00 64.42  ? 118 LEU R CD2 1 
ATOM   927  N N   . THR A 1 124 ? 161.969 155.064 140.378 1.00 42.72  ? 119 THR R N   1 
ATOM   928  C CA  . THR A 1 124 ? 163.420 154.955 140.499 1.00 38.92  ? 119 THR R CA  1 
ATOM   929  C C   . THR A 1 124 ? 163.868 155.082 141.953 1.00 55.30  ? 119 THR R C   1 
ATOM   930  O O   . THR A 1 124 ? 164.765 154.354 142.403 1.00 65.54  ? 119 THR R O   1 
ATOM   931  C CB  . THR A 1 124 ? 164.093 156.016 139.631 1.00 34.42  ? 119 THR R CB  1 
ATOM   932  O OG1 . THR A 1 124 ? 164.006 155.629 138.255 1.00 50.01  ? 119 THR R OG1 1 
ATOM   933  C CG2 . THR A 1 124 ? 165.550 156.186 140.011 1.00 48.20  ? 119 THR R CG2 1 
ATOM   934  N N   . VAL A 1 125 ? 163.254 156.001 142.701 1.00 62.10  ? 120 VAL R N   1 
ATOM   935  C CA  . VAL A 1 125 ? 163.619 156.187 144.104 1.00 59.32  ? 120 VAL R CA  1 
ATOM   936  C C   . VAL A 1 125 ? 163.330 154.924 144.909 1.00 57.24  ? 120 VAL R C   1 
ATOM   937  O O   . VAL A 1 125 ? 164.154 154.488 145.726 1.00 63.15  ? 120 VAL R O   1 
ATOM   938  C CB  . VAL A 1 125 ? 162.891 157.411 144.689 1.00 60.62  ? 120 VAL R CB  1 
ATOM   939  C CG1 . VAL A 1 125 ? 163.019 157.434 146.198 1.00 61.11  ? 120 VAL R CG1 1 
ATOM   940  C CG2 . VAL A 1 125 ? 163.449 158.690 144.089 1.00 64.88  ? 120 VAL R CG2 1 
ATOM   941  N N   . VAL A 1 126 ? 162.159 154.317 144.692 1.00 49.98  ? 121 VAL R N   1 
ATOM   942  C CA  . VAL A 1 126 ? 161.833 153.072 145.384 1.00 50.93  ? 121 VAL R CA  1 
ATOM   943  C C   . VAL A 1 126 ? 162.847 151.986 145.039 1.00 58.66  ? 121 VAL R C   1 
ATOM   944  O O   . VAL A 1 126 ? 163.300 151.236 145.917 1.00 64.59  ? 121 VAL R O   1 
ATOM   945  C CB  . VAL A 1 126 ? 160.395 152.634 145.053 1.00 48.90  ? 121 VAL R CB  1 
ATOM   946  C CG1 . VAL A 1 126 ? 160.202 151.157 145.346 1.00 52.42  ? 121 VAL R CG1 1 
ATOM   947  C CG2 . VAL A 1 126 ? 159.399 153.456 145.844 1.00 49.89  ? 121 VAL R CG2 1 
ATOM   948  N N   . ALA A 1 127 ? 163.221 151.883 143.760 1.00 53.95  ? 122 ALA R N   1 
ATOM   949  C CA  . ALA A 1 127 ? 164.179 150.855 143.360 1.00 44.09  ? 122 ALA R CA  1 
ATOM   950  C C   . ALA A 1 127 ? 165.528 151.050 144.044 1.00 43.59  ? 122 ALA R C   1 
ATOM   951  O O   . ALA A 1 127 ? 166.134 150.084 144.531 1.00 53.27  ? 122 ALA R O   1 
ATOM   952  C CB  . ALA A 1 127 ? 164.344 150.852 141.842 1.00 43.17  ? 122 ALA R CB  1 
ATOM   953  N N   . VAL A 1 128 ? 166.014 152.291 144.096 1.00 38.26  ? 123 VAL R N   1 
ATOM   954  C CA  . VAL A 1 128 ? 167.310 152.546 144.721 1.00 36.43  ? 123 VAL R CA  1 
ATOM   955  C C   . VAL A 1 128 ? 167.249 152.274 146.221 1.00 44.13  ? 123 VAL R C   1 
ATOM   956  O O   . VAL A 1 128 ? 168.203 151.744 146.810 1.00 55.02  ? 123 VAL R O   1 
ATOM   957  C CB  . VAL A 1 128 ? 167.781 153.978 144.420 1.00 41.00  ? 123 VAL R CB  1 
ATOM   958  C CG1 . VAL A 1 128 ? 169.095 154.259 145.121 1.00 47.12  ? 123 VAL R CG1 1 
ATOM   959  C CG2 . VAL A 1 128 ? 167.931 154.179 142.924 1.00 45.19  ? 123 VAL R CG2 1 
ATOM   960  N N   . ALA A 1 129 ? 166.131 152.623 146.864 1.00 53.45  ? 124 ALA R N   1 
ATOM   961  C CA  . ALA A 1 129 ? 165.983 152.323 148.285 1.00 54.19  ? 124 ALA R CA  1 
ATOM   962  C C   . ALA A 1 129 ? 166.021 150.820 148.537 1.00 59.54  ? 124 ALA R C   1 
ATOM   963  O O   . ALA A 1 129 ? 166.672 150.355 149.483 1.00 68.07  ? 124 ALA R O   1 
ATOM   964  C CB  . ALA A 1 129 ? 164.691 152.920 148.821 1.00 50.00  ? 124 ALA R CB  1 
ATOM   965  N N   . ARG A 1 130 ? 165.337 150.042 147.694 1.00 53.59  ? 125 ARG R N   1 
ATOM   966  C CA  . ARG A 1 130 ? 165.371 148.591 147.852 1.00 51.23  ? 125 ARG R CA  1 
ATOM   967  C C   . ARG A 1 130 ? 166.780 148.047 147.654 1.00 57.16  ? 125 ARG R C   1 
ATOM   968  O O   . ARG A 1 130 ? 167.212 147.139 148.376 1.00 65.61  ? 125 ARG R O   1 
ATOM   969  C CB  . ARG A 1 130 ? 164.399 147.928 146.881 1.00 52.39  ? 125 ARG R CB  1 
ATOM   970  C CG  . ARG A 1 130 ? 163.050 147.621 147.488 1.00 56.69  ? 125 ARG R CG  1 
ATOM   971  C CD  . ARG A 1 130 ? 162.040 147.245 146.424 1.00 62.48  ? 125 ARG R CD  1 
ATOM   972  N NE  . ARG A 1 130 ? 160.723 147.801 146.704 1.00 64.13  ? 125 ARG R NE  1 
ATOM   973  C CZ  . ARG A 1 130 ? 159.637 147.549 145.987 1.00 62.42  ? 125 ARG R CZ  1 
ATOM   974  N NH1 . ARG A 1 130 ? 159.674 146.747 144.936 1.00 62.95  ? 125 ARG R NH1 1 
ATOM   975  N NH2 . ARG A 1 130 ? 158.484 148.111 146.337 1.00 59.27  ? 125 ARG R NH2 1 
ATOM   976  N N   . TYR A 1 131 ? 167.511 148.584 146.675 1.00 51.26  ? 126 TYR R N   1 
ATOM   977  C CA  . TYR A 1 131 ? 168.886 148.142 146.469 1.00 44.66  ? 126 TYR R CA  1 
ATOM   978  C C   . TYR A 1 131 ? 169.742 148.412 147.697 1.00 48.84  ? 126 TYR R C   1 
ATOM   979  O O   . TYR A 1 131 ? 170.516 147.547 148.128 1.00 59.15  ? 126 TYR R O   1 
ATOM   980  C CB  . TYR A 1 131 ? 169.484 148.831 145.245 1.00 53.88  ? 126 TYR R CB  1 
ATOM   981  C CG  . TYR A 1 131 ? 170.991 148.740 145.165 1.00 52.97  ? 126 TYR R CG  1 
ATOM   982  C CD1 . TYR A 1 131 ? 171.608 147.604 144.672 1.00 53.01  ? 126 TYR R CD1 1 
ATOM   983  C CD2 . TYR A 1 131 ? 171.794 149.797 145.564 1.00 52.89  ? 126 TYR R CD2 1 
ATOM   984  C CE1 . TYR A 1 131 ? 172.979 147.517 144.591 1.00 52.59  ? 126 TYR R CE1 1 
ATOM   985  C CE2 . TYR A 1 131 ? 173.167 149.718 145.486 1.00 52.85  ? 126 TYR R CE2 1 
ATOM   986  C CZ  . TYR A 1 131 ? 173.753 148.576 144.998 1.00 54.77  ? 126 TYR R CZ  1 
ATOM   987  O OH  . TYR A 1 131 ? 175.122 148.490 144.918 1.00 62.82  ? 126 TYR R OH  1 
ATOM   988  N N   . PHE A 1 132 ? 169.615 149.606 148.279 1.00 54.37  ? 127 PHE R N   1 
ATOM   989  C CA  . PHE A 1 132 ? 170.415 149.926 149.457 1.00 52.50  ? 127 PHE R CA  1 
ATOM   990  C C   . PHE A 1 132 ? 169.990 149.109 150.669 1.00 51.58  ? 127 PHE R C   1 
ATOM   991  O O   . PHE A 1 132 ? 170.789 148.915 151.591 1.00 55.24  ? 127 PHE R O   1 
ATOM   992  C CB  . PHE A 1 132 ? 170.337 151.418 149.767 1.00 59.38  ? 127 PHE R CB  1 
ATOM   993  C CG  . PHE A 1 132 ? 171.517 152.198 149.270 1.00 61.79  ? 127 PHE R CG  1 
ATOM   994  C CD1 . PHE A 1 132 ? 172.765 152.021 149.835 1.00 61.66  ? 127 PHE R CD1 1 
ATOM   995  C CD2 . PHE A 1 132 ? 171.378 153.104 148.236 1.00 58.59  ? 127 PHE R CD2 1 
ATOM   996  C CE1 . PHE A 1 132 ? 173.851 152.735 149.381 1.00 61.96  ? 127 PHE R CE1 1 
ATOM   997  C CE2 . PHE A 1 132 ? 172.461 153.820 147.779 1.00 60.09  ? 127 PHE R CE2 1 
ATOM   998  C CZ  . PHE A 1 132 ? 173.700 153.635 148.352 1.00 63.65  ? 127 PHE R CZ  1 
ATOM   999  N N   . ARG A 1 133 ? 168.746 148.631 150.698 1.00 57.33  ? 128 ARG R N   1 
ATOM   1000 C CA  . ARG A 1 133 ? 168.342 147.748 151.789 1.00 49.75  ? 128 ARG R CA  1 
ATOM   1001 C C   . ARG A 1 133 ? 168.881 146.331 151.615 1.00 51.75  ? 128 ARG R C   1 
ATOM   1002 O O   . ARG A 1 133 ? 169.236 145.680 152.602 1.00 62.99  ? 128 ARG R O   1 
ATOM   1003 C CB  . ARG A 1 133 ? 166.821 147.718 151.917 1.00 55.30  ? 128 ARG R CB  1 
ATOM   1004 C CG  . ARG A 1 133 ? 166.275 148.650 152.980 1.00 56.94  ? 128 ARG R CG  1 
ATOM   1005 C CD  . ARG A 1 133 ? 164.985 149.311 152.542 1.00 56.74  ? 128 ARG R CD  1 
ATOM   1006 N NE  . ARG A 1 133 ? 164.598 150.391 153.441 1.00 61.48  ? 128 ARG R NE  1 
ATOM   1007 C CZ  . ARG A 1 133 ? 163.588 150.326 154.297 1.00 69.07  ? 128 ARG R CZ  1 
ATOM   1008 N NH1 . ARG A 1 133 ? 162.837 149.242 154.400 1.00 70.38  ? 128 ARG R NH1 1 
ATOM   1009 N NH2 . ARG A 1 133 ? 163.325 151.375 155.070 1.00 71.68  ? 128 ARG R NH2 1 
ATOM   1010 N N   . VAL A 1 134 ? 168.947 145.833 150.381 1.00 51.01  ? 129 VAL R N   1 
ATOM   1011 C CA  . VAL A 1 134 ? 169.265 144.418 150.192 1.00 41.32  ? 129 VAL R CA  1 
ATOM   1012 C C   . VAL A 1 134 ? 170.765 144.185 150.045 1.00 38.92  ? 129 VAL R C   1 
ATOM   1013 O O   . VAL A 1 134 ? 171.277 143.135 150.446 1.00 40.92  ? 129 VAL R O   1 
ATOM   1014 C CB  . VAL A 1 134 ? 168.496 143.856 148.985 1.00 52.15  ? 129 VAL R CB  1 
ATOM   1015 C CG1 . VAL A 1 134 ? 168.714 142.359 148.867 1.00 53.59  ? 129 VAL R CG1 1 
ATOM   1016 C CG2 . VAL A 1 134 ? 167.023 144.158 149.118 1.00 53.64  ? 129 VAL R CG2 1 
ATOM   1017 N N   . VAL A 1 135 ? 171.502 145.144 149.485 1.00 51.86  ? 130 VAL R N   1 
ATOM   1018 C CA  . VAL A 1 135 ? 172.886 144.879 149.102 1.00 47.34  ? 130 VAL R CA  1 
ATOM   1019 C C   . VAL A 1 135 ? 173.858 145.513 150.089 1.00 52.76  ? 130 VAL R C   1 
ATOM   1020 O O   . VAL A 1 135 ? 174.992 145.046 150.246 1.00 59.39  ? 130 VAL R O   1 
ATOM   1021 C CB  . VAL A 1 135 ? 173.154 145.363 147.666 1.00 60.39  ? 130 VAL R CB  1 
ATOM   1022 C CG1 . VAL A 1 135 ? 174.556 144.980 147.213 1.00 61.83  ? 130 VAL R CG1 1 
ATOM   1023 C CG2 . VAL A 1 135 ? 172.113 144.787 146.723 1.00 64.30  ? 130 VAL R CG2 1 
ATOM   1024 N N   . HIS A 1 136 ? 173.423 146.567 150.780 1.00 65.48  ? 131 HIS R N   1 
ATOM   1025 C CA  . HIS A 1 136 ? 174.223 147.239 151.802 1.00 68.62  ? 131 HIS R CA  1 
ATOM   1026 C C   . HIS A 1 136 ? 173.389 147.287 153.077 1.00 70.76  ? 131 HIS R C   1 
ATOM   1027 O O   . HIS A 1 136 ? 172.858 148.345 153.447 1.00 75.00  ? 131 HIS R O   1 
ATOM   1028 C CB  . HIS A 1 136 ? 174.647 148.635 151.351 1.00 72.14  ? 131 HIS R CB  1 
ATOM   1029 C CG  . HIS A 1 136 ? 175.344 148.654 150.027 1.00 72.22  ? 131 HIS R CG  1 
ATOM   1030 N ND1 . HIS A 1 136 ? 176.699 148.443 149.895 1.00 68.19  ? 131 HIS R ND1 1 
ATOM   1031 C CD2 . HIS A 1 136 ? 174.872 148.857 148.774 1.00 73.17  ? 131 HIS R CD2 1 
ATOM   1032 C CE1 . HIS A 1 136 ? 177.032 148.515 148.619 1.00 71.23  ? 131 HIS R CE1 1 
ATOM   1033 N NE2 . HIS A 1 136 ? 175.943 148.766 147.918 1.00 74.82  ? 131 HIS R NE2 1 
ATOM   1034 N N   . PRO A 1 137 ? 173.255 146.158 153.776 1.00 60.44  ? 132 PRO R N   1 
ATOM   1035 C CA  . PRO A 1 137 ? 172.253 146.074 154.849 1.00 56.81  ? 132 PRO R CA  1 
ATOM   1036 C C   . PRO A 1 137 ? 172.538 146.964 156.042 1.00 68.69  ? 132 PRO R C   1 
ATOM   1037 O O   . PRO A 1 137 ? 171.610 147.277 156.798 1.00 72.71  ? 132 PRO R O   1 
ATOM   1038 C CB  . PRO A 1 137 ? 172.290 144.591 155.238 1.00 57.41  ? 132 PRO R CB  1 
ATOM   1039 C CG  . PRO A 1 137 ? 173.661 144.148 154.874 1.00 68.80  ? 132 PRO R CG  1 
ATOM   1040 C CD  . PRO A 1 137 ? 174.025 144.911 153.636 1.00 63.48  ? 132 PRO R CD  1 
ATOM   1041 N N   . HIS A 1 138 ? 173.785 147.382 156.242 1.00 79.45  ? 133 HIS R N   1 
ATOM   1042 C CA  . HIS A 1 138 ? 174.163 148.137 157.429 1.00 75.58  ? 133 HIS R CA  1 
ATOM   1043 C C   . HIS A 1 138 ? 174.264 149.635 157.194 1.00 75.52  ? 133 HIS R C   1 
ATOM   1044 O O   . HIS A 1 138 ? 174.551 150.374 158.140 1.00 76.56  ? 133 HIS R O   1 
ATOM   1045 C CB  . HIS A 1 138 ? 175.495 147.623 157.978 1.00 66.88  ? 133 HIS R CB  1 
ATOM   1046 C CG  . HIS A 1 138 ? 175.452 146.197 158.419 1.00 62.71  ? 133 HIS R CG  1 
ATOM   1047 N ND1 . HIS A 1 138 ? 176.363 145.258 157.990 1.00 69.03  ? 133 HIS R ND1 1 
ATOM   1048 C CD2 . HIS A 1 138 ? 174.604 145.549 159.249 1.00 67.00  ? 133 HIS R CD2 1 
ATOM   1049 C CE1 . HIS A 1 138 ? 176.081 144.092 158.541 1.00 73.81  ? 133 HIS R CE1 1 
ATOM   1050 N NE2 . HIS A 1 138 ? 175.018 144.241 159.309 1.00 75.45  ? 133 HIS R NE2 1 
ATOM   1051 N N   . HIS A 1 139 ? 174.045 150.103 155.970 1.00 89.00  ? 134 HIS R N   1 
ATOM   1052 C CA  . HIS A 1 139 ? 174.173 151.526 155.700 1.00 91.44  ? 134 HIS R CA  1 
ATOM   1053 C C   . HIS A 1 139 ? 173.090 152.306 156.436 1.00 92.98  ? 134 HIS R C   1 
ATOM   1054 O O   . HIS A 1 139 ? 171.963 151.836 156.613 1.00 93.46  ? 134 HIS R O   1 
ATOM   1055 C CB  . HIS A 1 139 ? 174.094 151.803 154.201 1.00 91.43  ? 134 HIS R CB  1 
ATOM   1056 C CG  . HIS A 1 139 ? 174.695 153.113 153.802 1.00 92.53  ? 134 HIS R CG  1 
ATOM   1057 N ND1 . HIS A 1 139 ? 173.937 154.185 153.382 1.00 94.14  ? 134 HIS R ND1 1 
ATOM   1058 C CD2 . HIS A 1 139 ? 175.985 153.524 153.757 1.00 90.59  ? 134 HIS R CD2 1 
ATOM   1059 C CE1 . HIS A 1 139 ? 174.733 155.200 153.097 1.00 93.32  ? 134 HIS R CE1 1 
ATOM   1060 N NE2 . HIS A 1 139 ? 175.980 154.825 153.316 1.00 93.86  ? 134 HIS R NE2 1 
ATOM   1061 N N   . ALA A 1 140 ? 173.449 153.513 156.875 1.00 90.59  ? 135 ALA R N   1 
ATOM   1062 C CA  . ALA A 1 140 ? 172.533 154.341 157.647 1.00 90.43  ? 135 ALA R CA  1 
ATOM   1063 C C   . ALA A 1 140 ? 171.367 154.867 156.824 1.00 86.67  ? 135 ALA R C   1 
ATOM   1064 O O   . ALA A 1 140 ? 170.414 155.393 157.407 1.00 84.99  ? 135 ALA R O   1 
ATOM   1065 C CB  . ALA A 1 140 ? 173.289 155.514 158.273 1.00 90.78  ? 135 ALA R CB  1 
ATOM   1066 N N   . LEU A 1 141 ? 171.415 154.739 155.496 1.00 82.91  ? 136 LEU R N   1 
ATOM   1067 C CA  . LEU A 1 141 ? 170.365 155.308 154.659 1.00 86.47  ? 136 LEU R CA  1 
ATOM   1068 C C   . LEU A 1 141 ? 169.014 154.655 154.927 1.00 92.36  ? 136 LEU R C   1 
ATOM   1069 O O   . LEU A 1 141 ? 167.968 155.278 154.713 1.00 95.91  ? 136 LEU R O   1 
ATOM   1070 C CB  . LEU A 1 141 ? 170.747 155.180 153.185 1.00 86.35  ? 136 LEU R CB  1 
ATOM   1071 C CG  . LEU A 1 141 ? 169.720 155.621 152.142 1.00 89.50  ? 136 LEU R CG  1 
ATOM   1072 C CD1 . LEU A 1 141 ? 169.402 157.095 152.303 1.00 88.54  ? 136 LEU R CD1 1 
ATOM   1073 C CD2 . LEU A 1 141 ? 170.220 155.331 150.739 1.00 85.77  ? 136 LEU R CD2 1 
ATOM   1074 N N   . ASN A 1 142 ? 169.012 153.410 155.406 1.00 88.86  ? 137 ASN R N   1 
ATOM   1075 C CA  . ASN A 1 142 ? 167.756 152.747 155.733 1.00 85.25  ? 137 ASN R CA  1 
ATOM   1076 C C   . ASN A 1 142 ? 167.159 153.246 157.042 1.00 89.51  ? 137 ASN R C   1 
ATOM   1077 O O   . ASN A 1 142 ? 165.991 152.960 157.323 1.00 88.69  ? 137 ASN R O   1 
ATOM   1078 C CB  . ASN A 1 142 ? 167.964 151.236 155.800 1.00 88.69  ? 137 ASN R CB  1 
ATOM   1079 C CG  . ASN A 1 142 ? 169.021 150.752 154.832 1.00 91.62  ? 137 ASN R CG  1 
ATOM   1080 O OD1 . ASN A 1 142 ? 168.857 150.849 153.617 1.00 93.83  ? 137 ASN R OD1 1 
ATOM   1081 N ND2 . ASN A 1 142 ? 170.116 150.224 155.367 1.00 87.09  ? 137 ASN R ND2 1 
ATOM   1082 N N   . LYS A 1 143 ? 167.929 153.980 157.845 1.00 95.55  ? 138 LYS R N   1 
ATOM   1083 C CA  . LYS A 1 143 ? 167.475 154.470 159.141 1.00 94.74  ? 138 LYS R CA  1 
ATOM   1084 C C   . LYS A 1 143 ? 167.257 155.978 159.164 1.00 89.60  ? 138 LYS R C   1 
ATOM   1085 O O   . LYS A 1 143 ? 167.164 156.560 160.250 1.00 91.50  ? 138 LYS R O   1 
ATOM   1086 C CB  . LYS A 1 143 ? 168.471 154.079 160.236 1.00 93.42  ? 138 LYS R CB  1 
ATOM   1087 C CG  . LYS A 1 143 ? 169.193 152.764 160.001 1.00 91.13  ? 138 LYS R CG  1 
ATOM   1088 C CD  . LYS A 1 143 ? 170.372 152.617 160.953 1.00 92.02  ? 138 LYS R CD  1 
ATOM   1089 C CE  . LYS A 1 143 ? 171.511 151.841 160.314 1.00 93.39  ? 138 LYS R CE  1 
ATOM   1090 N NZ  . LYS A 1 143 ? 171.333 150.370 160.456 1.00 91.84  ? 138 LYS R NZ  1 
ATOM   1091 N N   . ILE A 1 144 ? 167.183 156.629 158.000 1.00 85.08  ? 139 ILE R N   1 
ATOM   1092 C CA  . ILE A 1 144 ? 166.979 158.070 157.981 1.00 86.57  ? 139 ILE R CA  1 
ATOM   1093 C C   . ILE A 1 144 ? 165.593 158.412 158.522 1.00 90.06  ? 139 ILE R C   1 
ATOM   1094 O O   . ILE A 1 144 ? 164.654 157.609 158.458 1.00 92.66  ? 139 ILE R O   1 
ATOM   1095 C CB  . ILE A 1 144 ? 167.176 158.644 156.567 1.00 86.80  ? 139 ILE R CB  1 
ATOM   1096 C CG1 . ILE A 1 144 ? 165.985 158.295 155.671 1.00 88.58  ? 139 ILE R CG1 1 
ATOM   1097 C CG2 . ILE A 1 144 ? 168.489 158.164 155.975 1.00 88.86  ? 139 ILE R CG2 1 
ATOM   1098 C CD1 . ILE A 1 144 ? 166.267 158.427 154.191 1.00 88.27  ? 139 ILE R CD1 1 
ATOM   1099 N N   . SER A 1 145 ? 165.473 159.617 159.073 1.00 97.42  ? 140 SER R N   1 
ATOM   1100 C CA  . SER A 1 145 ? 164.224 160.065 159.667 1.00 97.71  ? 140 SER R CA  1 
ATOM   1101 C C   . SER A 1 145 ? 163.227 160.466 158.582 1.00 96.82  ? 140 SER R C   1 
ATOM   1102 O O   . SER A 1 145 ? 163.567 160.620 157.406 1.00 100.39 ? 140 SER R O   1 
ATOM   1103 C CB  . SER A 1 145 ? 164.475 161.236 160.614 1.00 98.26  ? 140 SER R CB  1 
ATOM   1104 O OG  . SER A 1 145 ? 164.600 162.451 159.896 1.00 97.96  ? 140 SER R OG  1 
ATOM   1105 N N   . ASN A 1 146 ? 161.969 160.634 158.997 1.00 79.35  ? 141 ASN R N   1 
ATOM   1106 C CA  . ASN A 1 146 ? 160.935 161.083 158.072 1.00 81.35  ? 141 ASN R CA  1 
ATOM   1107 C C   . ASN A 1 146 ? 161.184 162.500 157.574 1.00 85.81  ? 141 ASN R C   1 
ATOM   1108 O O   . ASN A 1 146 ? 160.675 162.869 156.509 1.00 89.25  ? 141 ASN R O   1 
ATOM   1109 C CB  . ASN A 1 146 ? 159.561 161.000 158.735 1.00 79.35  ? 141 ASN R CB  1 
ATOM   1110 C CG  . ASN A 1 146 ? 159.218 159.598 159.181 1.00 76.73  ? 141 ASN R CG  1 
ATOM   1111 O OD1 . ASN A 1 146 ? 160.066 158.709 159.169 1.00 82.11  ? 141 ASN R OD1 1 
ATOM   1112 N ND2 . ASN A 1 146 ? 157.967 159.389 159.568 1.00 76.40  ? 141 ASN R ND2 1 
ATOM   1113 N N   . ARG A 1 147 ? 161.948 163.299 158.323 1.00 96.65  ? 142 ARG R N   1 
ATOM   1114 C CA  . ARG A 1 147 ? 162.285 164.642 157.866 1.00 102.02 ? 142 ARG R CA  1 
ATOM   1115 C C   . ARG A 1 147 ? 163.094 164.587 156.578 1.00 99.91  ? 142 ARG R C   1 
ATOM   1116 O O   . ARG A 1 147 ? 162.851 165.365 155.646 1.00 105.28 ? 142 ARG R O   1 
ATOM   1117 C CB  . ARG A 1 147 ? 163.055 165.385 158.957 1.00 103.82 ? 142 ARG R CB  1 
ATOM   1118 C CG  . ARG A 1 147 ? 163.516 166.780 158.564 1.00 104.68 ? 142 ARG R CG  1 
ATOM   1119 C CD  . ARG A 1 147 ? 162.340 167.653 158.148 1.00 105.92 ? 142 ARG R CD  1 
ATOM   1120 N NE  . ARG A 1 147 ? 161.247 167.605 159.114 1.00 108.09 ? 142 ARG R NE  1 
ATOM   1121 C CZ  . ARG A 1 147 ? 161.287 168.137 160.329 1.00 105.50 ? 142 ARG R CZ  1 
ATOM   1122 N NH1 . ARG A 1 147 ? 162.351 168.793 160.763 1.00 105.57 ? 142 ARG R NH1 1 
ATOM   1123 N NH2 . ARG A 1 147 ? 160.230 168.013 161.126 1.00 103.09 ? 142 ARG R NH2 1 
ATOM   1124 N N   . THR A 1 148 ? 164.057 163.666 156.506 1.00 89.44  ? 143 THR R N   1 
ATOM   1125 C CA  . THR A 1 148 ? 164.804 163.478 155.269 1.00 96.55  ? 143 THR R CA  1 
ATOM   1126 C C   . THR A 1 148 ? 163.900 163.005 154.139 1.00 98.36  ? 143 THR R C   1 
ATOM   1127 O O   . THR A 1 148 ? 164.100 163.398 152.985 1.00 95.93  ? 143 THR R O   1 
ATOM   1128 C CB  . THR A 1 148 ? 165.944 162.486 155.488 1.00 98.79  ? 143 THR R CB  1 
ATOM   1129 O OG1 . THR A 1 148 ? 166.534 162.710 156.774 1.00 96.91  ? 143 THR R OG1 1 
ATOM   1130 C CG2 . THR A 1 148 ? 167.009 162.656 154.414 1.00 96.10  ? 143 THR R CG2 1 
ATOM   1131 N N   . ALA A 1 149 ? 162.900 162.175 154.448 1.00 101.39 ? 144 ALA R N   1 
ATOM   1132 C CA  . ALA A 1 149 ? 161.952 161.742 153.426 1.00 99.41  ? 144 ALA R CA  1 
ATOM   1133 C C   . ALA A 1 149 ? 161.182 162.927 152.859 1.00 100.25 ? 144 ALA R C   1 
ATOM   1134 O O   . ALA A 1 149 ? 161.040 163.066 151.637 1.00 102.18 ? 144 ALA R O   1 
ATOM   1135 C CB  . ALA A 1 149 ? 160.989 160.706 154.006 1.00 93.23  ? 144 ALA R CB  1 
ATOM   1136 N N   . ALA A 1 150 ? 160.681 163.798 153.738 1.00 91.40  ? 145 ALA R N   1 
ATOM   1137 C CA  . ALA A 1 150 ? 159.956 164.977 153.278 1.00 91.01  ? 145 ALA R CA  1 
ATOM   1138 C C   . ALA A 1 150 ? 160.856 165.900 152.466 1.00 88.41  ? 145 ALA R C   1 
ATOM   1139 O O   . ALA A 1 150 ? 160.435 166.438 151.435 1.00 87.28  ? 145 ALA R O   1 
ATOM   1140 C CB  . ALA A 1 150 ? 159.357 165.723 154.470 1.00 90.74  ? 145 ALA R CB  1 
ATOM   1141 N N   . ILE A 1 151 ? 162.101 166.090 152.910 1.00 90.66  ? 146 ILE R N   1 
ATOM   1142 C CA  . ILE A 1 151 ? 163.025 166.960 152.183 1.00 93.44  ? 146 ILE R CA  1 
ATOM   1143 C C   . ILE A 1 151 ? 163.316 166.399 150.795 1.00 101.59 ? 146 ILE R C   1 
ATOM   1144 O O   . ILE A 1 151 ? 163.321 167.136 149.800 1.00 104.67 ? 146 ILE R O   1 
ATOM   1145 C CB  . ILE A 1 151 ? 164.316 167.166 152.996 1.00 95.34  ? 146 ILE R CB  1 
ATOM   1146 C CG1 . ILE A 1 151 ? 164.037 168.033 154.225 1.00 97.50  ? 146 ILE R CG1 1 
ATOM   1147 C CG2 . ILE A 1 151 ? 165.399 167.797 152.136 1.00 95.03  ? 146 ILE R CG2 1 
ATOM   1148 C CD1 . ILE A 1 151 ? 165.142 168.002 155.258 1.00 94.86  ? 146 ILE R CD1 1 
ATOM   1149 N N   . ILE A 1 152 ? 163.565 165.090 150.703 1.00 93.54  ? 147 ILE R N   1 
ATOM   1150 C CA  . ILE A 1 152 ? 163.856 164.470 149.413 1.00 87.95  ? 147 ILE R CA  1 
ATOM   1151 C C   . ILE A 1 152 ? 162.649 164.563 148.489 1.00 88.14  ? 147 ILE R C   1 
ATOM   1152 O O   . ILE A 1 152 ? 162.783 164.862 147.293 1.00 91.67  ? 147 ILE R O   1 
ATOM   1153 C CB  . ILE A 1 152 ? 164.308 163.012 149.615 1.00 84.82  ? 147 ILE R CB  1 
ATOM   1154 C CG1 . ILE A 1 152 ? 165.720 162.971 150.200 1.00 88.17  ? 147 ILE R CG1 1 
ATOM   1155 C CG2 . ILE A 1 152 ? 164.254 162.244 148.305 1.00 89.30  ? 147 ILE R CG2 1 
ATOM   1156 C CD1 . ILE A 1 152 ? 166.067 161.657 150.865 1.00 91.33  ? 147 ILE R CD1 1 
ATOM   1157 N N   . SER A 1 153 ? 161.452 164.309 149.024 1.00 79.63  ? 148 SER R N   1 
ATOM   1158 C CA  . SER A 1 153 ? 160.245 164.423 148.215 1.00 82.31  ? 148 SER R CA  1 
ATOM   1159 C C   . SER A 1 153 ? 160.060 165.845 147.700 1.00 85.87  ? 148 SER R C   1 
ATOM   1160 O O   . SER A 1 153 ? 159.719 166.051 146.528 1.00 86.44  ? 148 SER R O   1 
ATOM   1161 C CB  . SER A 1 153 ? 159.030 163.985 149.029 1.00 80.61  ? 148 SER R CB  1 
ATOM   1162 O OG  . SER A 1 153 ? 159.120 162.617 149.383 1.00 83.65  ? 148 SER R OG  1 
ATOM   1163 N N   . CYS A 1 154 ? 160.286 166.839 148.562 1.00 86.47  ? 149 CYS R N   1 
ATOM   1164 C CA  . CYS A 1 154 ? 160.154 168.229 148.140 1.00 84.32  ? 149 CYS R CA  1 
ATOM   1165 C C   . CYS A 1 154 ? 161.166 168.575 147.057 1.00 81.97  ? 149 CYS R C   1 
ATOM   1166 O O   . CYS A 1 154 ? 160.831 169.256 146.082 1.00 87.46  ? 149 CYS R O   1 
ATOM   1167 C CB  . CYS A 1 154 ? 160.314 169.159 149.342 1.00 86.95  ? 149 CYS R CB  1 
ATOM   1168 S SG  . CYS A 1 154 ? 158.875 169.221 150.434 1.00 95.47  ? 149 CYS R SG  1 
ATOM   1169 N N   . LEU A 1 155 ? 162.410 168.115 147.209 1.00 75.83  ? 150 LEU R N   1 
ATOM   1170 C CA  . LEU A 1 155 ? 163.429 168.405 146.206 1.00 80.22  ? 150 LEU R CA  1 
ATOM   1171 C C   . LEU A 1 155 ? 163.075 167.778 144.862 1.00 89.27  ? 150 LEU R C   1 
ATOM   1172 O O   . LEU A 1 155 ? 163.228 168.414 143.810 1.00 89.26  ? 150 LEU R O   1 
ATOM   1173 C CB  . LEU A 1 155 ? 164.794 167.917 146.696 1.00 81.54  ? 150 LEU R CB  1 
ATOM   1174 C CG  . LEU A 1 155 ? 166.074 168.539 146.125 1.00 85.67  ? 150 LEU R CG  1 
ATOM   1175 C CD1 . LEU A 1 155 ? 167.254 168.199 147.021 1.00 85.09  ? 150 LEU R CD1 1 
ATOM   1176 C CD2 . LEU A 1 155 ? 166.357 168.082 144.701 1.00 85.01  ? 150 LEU R CD2 1 
ATOM   1177 N N   . LEU A 1 156 ? 162.601 166.528 144.875 1.00 90.60  ? 151 LEU R N   1 
ATOM   1178 C CA  . LEU A 1 156 ? 162.239 165.868 143.623 1.00 84.19  ? 151 LEU R CA  1 
ATOM   1179 C C   . LEU A 1 156 ? 161.047 166.550 142.960 1.00 86.22  ? 151 LEU R C   1 
ATOM   1180 O O   . LEU A 1 156 ? 161.029 166.739 141.734 1.00 86.93  ? 151 LEU R O   1 
ATOM   1181 C CB  . LEU A 1 156 ? 161.950 164.390 143.873 1.00 76.75  ? 151 LEU R CB  1 
ATOM   1182 C CG  . LEU A 1 156 ? 163.184 163.547 144.194 1.00 76.01  ? 151 LEU R CG  1 
ATOM   1183 C CD1 . LEU A 1 156 ? 162.785 162.235 144.847 1.00 81.51  ? 151 LEU R CD1 1 
ATOM   1184 C CD2 . LEU A 1 156 ? 164.012 163.303 142.946 1.00 78.84  ? 151 LEU R CD2 1 
ATOM   1185 N N   . TRP A 1 157 ? 160.046 166.936 143.754 1.00 71.02  ? 152 TRP R N   1 
ATOM   1186 C CA  . TRP A 1 157 ? 158.920 167.677 143.201 1.00 65.90  ? 152 TRP R CA  1 
ATOM   1187 C C   . TRP A 1 157 ? 159.391 168.991 142.594 1.00 69.48  ? 152 TRP R C   1 
ATOM   1188 O O   . TRP A 1 157 ? 158.942 169.384 141.510 1.00 76.24  ? 152 TRP R O   1 
ATOM   1189 C CB  . TRP A 1 157 ? 157.882 167.933 144.290 1.00 71.94  ? 152 TRP R CB  1 
ATOM   1190 C CG  . TRP A 1 157 ? 156.920 166.810 144.502 1.00 68.49  ? 152 TRP R CG  1 
ATOM   1191 C CD1 . TRP A 1 157 ? 156.747 166.094 145.648 1.00 73.64  ? 152 TRP R CD1 1 
ATOM   1192 C CD2 . TRP A 1 157 ? 155.990 166.277 143.554 1.00 58.62  ? 152 TRP R CD2 1 
ATOM   1193 N NE1 . TRP A 1 157 ? 155.772 165.146 145.473 1.00 71.94  ? 152 TRP R NE1 1 
ATOM   1194 C CE2 . TRP A 1 157 ? 155.290 165.239 144.195 1.00 66.57  ? 152 TRP R CE2 1 
ATOM   1195 C CE3 . TRP A 1 157 ? 155.681 166.576 142.226 1.00 59.98  ? 152 TRP R CE3 1 
ATOM   1196 C CZ2 . TRP A 1 157 ? 154.303 164.498 143.556 1.00 72.96  ? 152 TRP R CZ2 1 
ATOM   1197 C CZ3 . TRP A 1 157 ? 154.702 165.837 141.594 1.00 69.81  ? 152 TRP R CZ3 1 
ATOM   1198 C CH2 . TRP A 1 157 ? 154.025 164.811 142.257 1.00 74.17  ? 152 TRP R CH2 1 
ATOM   1199 N N   . GLY A 1 158 ? 160.308 169.677 143.276 1.00 80.79  ? 153 GLY R N   1 
ATOM   1200 C CA  . GLY A 1 158 ? 160.818 170.931 142.754 1.00 83.13  ? 153 GLY R CA  1 
ATOM   1201 C C   . GLY A 1 158 ? 161.525 170.763 141.425 1.00 85.00  ? 153 GLY R C   1 
ATOM   1202 O O   . GLY A 1 158 ? 161.312 171.544 140.495 1.00 87.36  ? 153 GLY R O   1 
ATOM   1203 N N   . ILE A 1 159 ? 162.377 169.740 141.312 1.00 86.15  ? 154 ILE R N   1 
ATOM   1204 C CA  . ILE A 1 159 ? 163.129 169.586 140.069 1.00 85.63  ? 154 ILE R CA  1 
ATOM   1205 C C   . ILE A 1 159 ? 162.199 169.204 138.924 1.00 85.39  ? 154 ILE R C   1 
ATOM   1206 O O   . ILE A 1 159 ? 162.322 169.737 137.813 1.00 88.52  ? 154 ILE R O   1 
ATOM   1207 C CB  . ILE A 1 159 ? 164.294 168.587 140.219 1.00 84.50  ? 154 ILE R CB  1 
ATOM   1208 C CG1 . ILE A 1 159 ? 164.851 168.211 138.845 1.00 83.07  ? 154 ILE R CG1 1 
ATOM   1209 C CG2 . ILE A 1 159 ? 163.867 167.333 140.912 1.00 83.83  ? 154 ILE R CG2 1 
ATOM   1210 C CD1 . ILE A 1 159 ? 165.999 167.229 138.898 1.00 85.03  ? 154 ILE R CD1 1 
ATOM   1211 N N   . THR A 1 160 ? 161.236 168.304 139.164 1.00 84.49  ? 155 THR R N   1 
ATOM   1212 C CA  . THR A 1 160 ? 160.336 167.950 138.066 1.00 86.13  ? 155 THR R CA  1 
ATOM   1213 C C   . THR A 1 160 ? 159.470 169.140 137.648 1.00 94.38  ? 155 THR R C   1 
ATOM   1214 O O   . THR A 1 160 ? 159.268 169.371 136.447 1.00 94.38  ? 155 THR R O   1 
ATOM   1215 C CB  . THR A 1 160 ? 159.469 166.737 138.420 1.00 84.37  ? 155 THR R CB  1 
ATOM   1216 O OG1 . THR A 1 160 ? 158.538 166.495 137.358 1.00 87.36  ? 155 THR R OG1 1 
ATOM   1217 C CG2 . THR A 1 160 ? 158.690 166.954 139.692 1.00 86.81  ? 155 THR R CG2 1 
ATOM   1218 N N   . ILE A 1 161 ? 158.972 169.924 138.614 1.00 94.53  ? 156 ILE R N   1 
ATOM   1219 C CA  . ILE A 1 161 ? 158.158 171.088 138.268 1.00 84.31  ? 156 ILE R CA  1 
ATOM   1220 C C   . ILE A 1 161 ? 158.981 172.104 137.491 1.00 83.90  ? 156 ILE R C   1 
ATOM   1221 O O   . ILE A 1 161 ? 158.532 172.636 136.467 1.00 87.01  ? 156 ILE R O   1 
ATOM   1222 C CB  . ILE A 1 161 ? 157.538 171.711 139.533 1.00 85.89  ? 156 ILE R CB  1 
ATOM   1223 C CG1 . ILE A 1 161 ? 156.431 170.815 140.091 1.00 85.44  ? 156 ILE R CG1 1 
ATOM   1224 C CG2 . ILE A 1 161 ? 156.993 173.099 139.237 1.00 87.52  ? 156 ILE R CG2 1 
ATOM   1225 C CD1 . ILE A 1 161 ? 156.141 171.043 141.559 1.00 88.67  ? 156 ILE R CD1 1 
ATOM   1226 N N   . GLY A 1 162 ? 160.196 172.391 137.958 1.00 84.81  ? 157 GLY R N   1 
ATOM   1227 C CA  . GLY A 1 162 ? 161.036 173.343 137.260 1.00 87.97  ? 157 GLY R CA  1 
ATOM   1228 C C   . GLY A 1 162 ? 161.407 172.890 135.865 1.00 89.56  ? 157 GLY R C   1 
ATOM   1229 O O   . GLY A 1 162 ? 161.529 173.712 134.953 1.00 91.96  ? 157 GLY R O   1 
ATOM   1230 N N   . LEU A 1 163 ? 161.592 171.583 135.674 1.00 90.15  ? 158 LEU R N   1 
ATOM   1231 C CA  . LEU A 1 163 ? 161.993 171.094 134.364 1.00 91.11  ? 158 LEU R CA  1 
ATOM   1232 C C   . LEU A 1 163 ? 160.821 171.032 133.394 1.00 89.25  ? 158 LEU R C   1 
ATOM   1233 O O   . LEU A 1 163 ? 161.023 171.163 132.182 1.00 88.79  ? 158 LEU R O   1 
ATOM   1234 C CB  . LEU A 1 163 ? 162.650 169.720 134.496 1.00 91.48  ? 158 LEU R CB  1 
ATOM   1235 C CG  . LEU A 1 163 ? 164.177 169.725 134.383 1.00 91.55  ? 158 LEU R CG  1 
ATOM   1236 C CD1 . LEU A 1 163 ? 164.636 169.878 132.945 1.00 92.34  ? 158 LEU R CD1 1 
ATOM   1237 C CD2 . LEU A 1 163 ? 164.785 170.813 135.260 1.00 90.99  ? 158 LEU R CD2 1 
ATOM   1238 N N   . THR A 1 164 ? 159.601 170.835 133.890 1.00 98.68  ? 159 THR R N   1 
ATOM   1239 C CA  . THR A 1 164 ? 158.440 170.773 133.011 1.00 101.13 ? 159 THR R CA  1 
ATOM   1240 C C   . THR A 1 164 ? 157.689 172.097 132.893 1.00 108.49 ? 159 THR R C   1 
ATOM   1241 O O   . THR A 1 164 ? 156.732 172.176 132.115 1.00 111.03 ? 159 THR R O   1 
ATOM   1242 C CB  . THR A 1 164 ? 157.470 169.687 133.485 1.00 102.27 ? 159 THR R CB  1 
ATOM   1243 O OG1 . THR A 1 164 ? 157.214 169.854 134.884 1.00 104.04 ? 159 THR R OG1 1 
ATOM   1244 C CG2 . THR A 1 164 ? 158.056 168.306 133.241 1.00 101.29 ? 159 THR R CG2 1 
ATOM   1245 N N   . VAL A 1 165 ? 158.094 173.136 133.630 1.00 110.90 ? 160 VAL R N   1 
ATOM   1246 C CA  . VAL A 1 165 ? 157.375 174.408 133.584 1.00 107.57 ? 160 VAL R CA  1 
ATOM   1247 C C   . VAL A 1 165 ? 157.471 175.097 132.226 1.00 106.24 ? 160 VAL R C   1 
ATOM   1248 O O   . VAL A 1 165 ? 156.803 176.113 132.004 1.00 103.95 ? 160 VAL R O   1 
ATOM   1249 C CB  . VAL A 1 165 ? 157.888 175.338 134.702 1.00 105.09 ? 160 VAL R CB  1 
ATOM   1250 C CG1 . VAL A 1 165 ? 159.149 176.066 134.258 1.00 104.67 ? 160 VAL R CG1 1 
ATOM   1251 C CG2 . VAL A 1 165 ? 156.804 176.320 135.128 1.00 102.51 ? 160 VAL R CG2 1 
ATOM   1252 N N   . HIS A 1 166 ? 158.283 174.569 131.306 1.00 98.82  ? 161 HIS R N   1 
ATOM   1253 C CA  . HIS A 1 166 ? 158.445 175.197 129.998 1.00 93.71  ? 161 HIS R CA  1 
ATOM   1254 C C   . HIS A 1 166 ? 157.126 175.302 129.241 1.00 93.30  ? 161 HIS R C   1 
ATOM   1255 O O   . HIS A 1 166 ? 156.929 176.247 128.470 1.00 94.09  ? 161 HIS R O   1 
ATOM   1256 C CB  . HIS A 1 166 ? 159.460 174.411 129.169 1.00 93.07  ? 161 HIS R CB  1 
ATOM   1257 C CG  . HIS A 1 166 ? 160.070 175.201 128.054 1.00 96.91  ? 161 HIS R CG  1 
ATOM   1258 N ND1 . HIS A 1 166 ? 160.724 174.610 126.995 1.00 98.96  ? 161 HIS R ND1 1 
ATOM   1259 C CD2 . HIS A 1 166 ? 160.124 176.535 127.833 1.00 99.52  ? 161 HIS R CD2 1 
ATOM   1260 C CE1 . HIS A 1 166 ? 161.155 175.546 126.169 1.00 101.25 ? 161 HIS R CE1 1 
ATOM   1261 N NE2 . HIS A 1 166 ? 160.804 176.723 126.655 1.00 101.39 ? 161 HIS R NE2 1 
ATOM   1262 N N   . LEU A 1 167 ? 156.217 174.351 129.444 1.00 97.26  ? 162 LEU R N   1 
ATOM   1263 C CA  . LEU A 1 167 ? 155.005 174.267 128.639 1.00 102.01 ? 162 LEU R CA  1 
ATOM   1264 C C   . LEU A 1 167 ? 153.882 175.178 129.119 1.00 102.52 ? 162 LEU R C   1 
ATOM   1265 O O   . LEU A 1 167 ? 152.873 175.300 128.417 1.00 104.48 ? 162 LEU R O   1 
ATOM   1266 C CB  . LEU A 1 167 ? 154.501 172.822 128.609 1.00 100.49 ? 162 LEU R CB  1 
ATOM   1267 C CG  . LEU A 1 167 ? 155.415 171.777 127.967 1.00 97.71  ? 162 LEU R CG  1 
ATOM   1268 C CD1 . LEU A 1 167 ? 154.635 170.511 127.666 1.00 101.34 ? 162 LEU R CD1 1 
ATOM   1269 C CD2 . LEU A 1 167 ? 156.051 172.325 126.704 1.00 97.75  ? 162 LEU R CD2 1 
ATOM   1270 N N   . LEU A 1 168 ? 154.019 175.819 130.279 1.00 101.28 ? 163 LEU R N   1 
ATOM   1271 C CA  . LEU A 1 168 ? 152.896 176.558 130.842 1.00 102.78 ? 163 LEU R CA  1 
ATOM   1272 C C   . LEU A 1 168 ? 152.729 177.951 130.249 1.00 106.07 ? 163 LEU R C   1 
ATOM   1273 O O   . LEU A 1 168 ? 151.746 178.626 130.572 1.00 107.40 ? 163 LEU R O   1 
ATOM   1274 C CB  . LEU A 1 168 ? 153.034 176.667 132.362 1.00 101.12 ? 163 LEU R CB  1 
ATOM   1275 C CG  . LEU A 1 168 ? 151.996 175.877 133.161 1.00 102.74 ? 163 LEU R CG  1 
ATOM   1276 C CD1 . LEU A 1 168 ? 152.038 176.254 134.635 1.00 103.68 ? 163 LEU R CD1 1 
ATOM   1277 C CD2 . LEU A 1 168 ? 150.602 176.082 132.587 1.00 97.99  ? 163 LEU R CD2 1 
ATOM   1278 N N   . LYS A 1 169 ? 153.611 178.319 129.319 1.00 103.39 ? 164 LYS R N   1 
ATOM   1279 C CA  . LYS A 1 169 ? 153.422 179.592 128.586 1.00 101.62 ? 164 LYS R CA  1 
ATOM   1280 C C   . LYS A 1 169 ? 152.811 179.197 127.244 1.00 101.39 ? 164 LYS R C   1 
ATOM   1281 O O   . LYS A 1 169 ? 153.133 179.850 126.235 1.00 99.47  ? 164 LYS R O   1 
ATOM   1282 C CB  . LYS A 1 169 ? 154.776 180.272 128.397 1.00 101.35 ? 164 LYS R CB  1 
ATOM   1283 C CG  . LYS A 1 169 ? 155.768 179.506 127.533 1.00 103.55 ? 164 LYS R CG  1 
ATOM   1284 C CD  . LYS A 1 169 ? 157.085 180.229 127.354 1.00 101.47 ? 164 LYS R CD  1 
ATOM   1285 C CE  . LYS A 1 169 ? 158.067 179.463 126.495 1.00 100.73 ? 164 LYS R CE  1 
ATOM   1286 N NZ  . LYS A 1 169 ? 159.345 180.196 126.339 1.00 98.02  ? 164 LYS R NZ  1 
ATOM   1287 N N   . LYS A 1 170 ? 151.948 178.178 127.237 1.00 120.51 ? 165 LYS R N   1 
ATOM   1288 C CA  . LYS A 1 170 ? 151.437 177.630 125.948 1.00 122.99 ? 165 LYS R CA  1 
ATOM   1289 C C   . LYS A 1 170 ? 150.552 178.609 125.176 1.00 122.66 ? 165 LYS R C   1 
ATOM   1290 O O   . LYS A 1 170 ? 149.749 179.309 125.812 1.00 122.87 ? 165 LYS R O   1 
ATOM   1291 C CB  . LYS A 1 170 ? 150.695 176.309 126.183 1.00 124.35 ? 165 LYS R CB  1 
ATOM   1292 N N   . LYS A 1 171 ? 150.709 178.629 123.851 1.00 111.33 ? 166 LYS R N   1 
ATOM   1293 C CA  . LYS A 1 171 ? 149.861 179.462 122.961 1.00 113.54 ? 166 LYS R CA  1 
ATOM   1294 C C   . LYS A 1 171 ? 148.470 178.831 122.911 1.00 113.55 ? 166 LYS R C   1 
ATOM   1295 O O   . LYS A 1 171 ? 148.375 177.604 123.093 1.00 111.12 ? 166 LYS R O   1 
ATOM   1296 C CB  . LYS A 1 171 ? 150.517 179.582 121.582 1.00 111.98 ? 166 LYS R CB  1 
ATOM   1297 C CG  . LYS A 1 171 ? 151.822 180.367 121.559 1.00 112.24 ? 166 LYS R CG  1 
ATOM   1298 C CD  . LYS A 1 171 ? 152.454 180.445 120.185 1.00 111.86 ? 166 LYS R CD  1 
ATOM   1299 C CE  . LYS A 1 171 ? 153.738 181.246 120.158 1.00 111.64 ? 166 LYS R CE  1 
ATOM   1300 N NZ  . LYS A 1 171 ? 154.339 181.280 118.804 1.00 110.72 ? 166 LYS R NZ  1 
ATOM   1301 N N   . MET A 1 172 ? 147.453 179.648 122.640 1.00 114.04 ? 167 MET R N   1 
ATOM   1302 C CA  . MET A 1 172 ? 146.045 179.169 122.641 1.00 111.60 ? 167 MET R CA  1 
ATOM   1303 C C   . MET A 1 172 ? 145.843 177.891 121.829 1.00 113.59 ? 167 MET R C   1 
ATOM   1304 O O   . MET A 1 172 ? 146.499 177.727 120.782 1.00 115.53 ? 167 MET R O   1 
ATOM   1305 C CB  . MET A 1 172 ? 145.146 180.181 121.923 1.00 111.79 ? 167 MET R CB  1 
ATOM   1306 C CG  . MET A 1 172 ? 145.039 181.508 122.645 1.00 116.76 ? 167 MET R CG  1 
ATOM   1307 S SD  . MET A 1 172 ? 144.354 181.326 124.310 1.00 125.67 ? 167 MET R SD  1 
ATOM   1308 C CE  . MET A 1 172 ? 142.681 180.816 123.920 1.00 116.00 ? 167 MET R CE  1 
ATOM   1309 N N   . PRO A 1 173 ? 144.877 177.032 122.209 1.00 97.70  ? 168 PRO R N   1 
ATOM   1310 C CA  . PRO A 1 173 ? 144.601 175.869 121.401 1.00 93.82  ? 168 PRO R CA  1 
ATOM   1311 C C   . PRO A 1 173 ? 144.648 176.347 119.951 1.00 97.28  ? 168 PRO R C   1 
ATOM   1312 O O   . PRO A 1 173 ? 143.993 177.326 119.651 1.00 96.30  ? 168 PRO R O   1 
ATOM   1313 C CB  . PRO A 1 173 ? 143.185 175.496 121.825 1.00 89.44  ? 168 PRO R CB  1 
ATOM   1314 C CG  . PRO A 1 173 ? 143.032 176.091 123.200 1.00 94.43  ? 168 PRO R CG  1 
ATOM   1315 C CD  . PRO A 1 173 ? 143.716 177.429 123.064 1.00 94.63  ? 168 PRO R CD  1 
ATOM   1316 N N   . ILE A 1 174 ? 145.367 175.636 119.079 1.00 111.70 ? 169 ILE R N   1 
ATOM   1317 C CA  . ILE A 1 174 ? 145.588 176.154 117.693 1.00 110.73 ? 169 ILE R CA  1 
ATOM   1318 C C   . ILE A 1 174 ? 144.469 175.658 116.782 1.00 111.12 ? 169 ILE R C   1 
ATOM   1319 O O   . ILE A 1 174 ? 144.064 174.491 116.932 1.00 111.71 ? 169 ILE R O   1 
ATOM   1320 C CB  . ILE A 1 174 ? 146.987 175.754 117.184 1.00 110.58 ? 169 ILE R CB  1 
ATOM   1321 C CG1 . ILE A 1 174 ? 148.097 176.436 117.988 1.00 109.15 ? 169 ILE R CG1 1 
ATOM   1322 C CG2 . ILE A 1 174 ? 147.125 176.019 115.691 1.00 111.25 ? 169 ILE R CG2 1 
ATOM   1323 C CD1 . ILE A 1 174 ? 149.477 175.889 117.714 1.00 110.76 ? 169 ILE R CD1 1 
ATOM   1324 N N   . GLN A 1 175 ? 144.003 176.504 115.862 1.00 101.47 ? 170 GLN R N   1 
ATOM   1325 C CA  . GLN A 1 175 ? 142.860 176.066 115.075 1.00 100.97 ? 170 GLN R CA  1 
ATOM   1326 C C   . GLN A 1 175 ? 143.302 175.714 113.661 1.00 98.18  ? 170 GLN R C   1 
ATOM   1327 O O   . GLN A 1 175 ? 143.968 176.511 112.992 1.00 99.10  ? 170 GLN R O   1 
ATOM   1328 C CB  . GLN A 1 175 ? 141.767 177.140 115.042 1.00 101.73 ? 170 GLN R CB  1 
ATOM   1329 C CG  . GLN A 1 175 ? 142.200 178.483 114.469 1.00 102.30 ? 170 GLN R CG  1 
ATOM   1330 C CD  . GLN A 1 175 ? 141.131 179.114 113.599 1.00 103.49 ? 170 GLN R CD  1 
ATOM   1331 O OE1 . GLN A 1 175 ? 140.845 178.636 112.502 1.00 102.70 ? 170 GLN R OE1 1 
ATOM   1332 N NE2 . GLN A 1 175 ? 140.533 180.195 114.086 1.00 102.86 ? 170 GLN R NE2 1 
ATOM   1333 N N   . ASN A 1 176 ? 142.951 174.510 113.224 1.00 101.10 ? 171 ASN R N   1 
ATOM   1334 C CA  . ASN A 1 176 ? 143.081 174.098 111.833 1.00 103.87 ? 171 ASN R CA  1 
ATOM   1335 C C   . ASN A 1 176 ? 141.677 173.939 111.267 1.00 103.87 ? 171 ASN R C   1 
ATOM   1336 O O   . ASN A 1 176 ? 140.931 173.044 111.682 1.00 100.87 ? 171 ASN R O   1 
ATOM   1337 C CB  . ASN A 1 176 ? 143.886 172.803 111.704 1.00 105.41 ? 171 ASN R CB  1 
ATOM   1338 C CG  . ASN A 1 176 ? 143.321 171.672 112.539 1.00 107.91 ? 171 ASN R CG  1 
ATOM   1339 O OD1 . ASN A 1 176 ? 142.692 171.901 113.571 1.00 109.40 ? 171 ASN R OD1 1 
ATOM   1340 N ND2 . ASN A 1 176 ? 143.539 170.440 112.091 1.00 107.17 ? 171 ASN R ND2 1 
ATOM   1341 N N   . GLY A 1 177 ? 141.319 174.808 110.328 1.00 106.99 ? 172 GLY R N   1 
ATOM   1342 C CA  . GLY A 1 177 ? 139.927 174.886 109.921 1.00 105.37 ? 172 GLY R CA  1 
ATOM   1343 C C   . GLY A 1 177 ? 139.078 175.249 111.121 1.00 104.11 ? 172 GLY R C   1 
ATOM   1344 O O   . GLY A 1 177 ? 139.338 176.235 111.818 1.00 102.17 ? 172 GLY R O   1 
ATOM   1345 N N   . GLY A 1 178 ? 138.055 174.441 111.377 1.00 116.64 ? 173 GLY R N   1 
ATOM   1346 C CA  . GLY A 1 178 ? 137.253 174.608 112.572 1.00 117.98 ? 173 GLY R CA  1 
ATOM   1347 C C   . GLY A 1 178 ? 137.753 173.772 113.733 1.00 118.76 ? 173 GLY R C   1 
ATOM   1348 O O   . GLY A 1 178 ? 137.358 173.992 114.882 1.00 116.24 ? 173 GLY R O   1 
ATOM   1349 N N   . ALA A 1 179 ? 138.627 172.811 113.444 1.00 111.18 ? 174 ALA R N   1 
ATOM   1350 C CA  . ALA A 1 179 ? 139.133 171.921 114.478 1.00 110.10 ? 174 ALA R CA  1 
ATOM   1351 C C   . ALA A 1 179 ? 140.212 172.612 115.306 1.00 106.14 ? 174 ALA R C   1 
ATOM   1352 O O   . ALA A 1 179 ? 140.799 173.615 114.898 1.00 101.50 ? 174 ALA R O   1 
ATOM   1353 C CB  . ALA A 1 179 ? 139.685 170.638 113.857 1.00 108.77 ? 174 ALA R CB  1 
ATOM   1354 N N   . ASN A 1 180 ? 140.483 172.047 116.479 1.00 100.31 ? 175 ASN R N   1 
ATOM   1355 C CA  . ASN A 1 180 ? 141.416 172.628 117.433 1.00 95.67  ? 175 ASN R CA  1 
ATOM   1356 C C   . ASN A 1 180 ? 142.391 171.569 117.929 1.00 98.77  ? 175 ASN R C   1 
ATOM   1357 O O   . ASN A 1 180 ? 141.995 170.441 118.231 1.00 97.58  ? 175 ASN R O   1 
ATOM   1358 C CB  . ASN A 1 180 ? 140.664 173.250 118.611 1.00 99.57  ? 175 ASN R CB  1 
ATOM   1359 C CG  . ASN A 1 180 ? 141.511 174.227 119.387 1.00 100.79 ? 175 ASN R CG  1 
ATOM   1360 O OD1 . ASN A 1 180 ? 142.731 174.243 119.254 1.00 97.04  ? 175 ASN R OD1 1 
ATOM   1361 N ND2 . ASN A 1 180 ? 140.866 175.055 120.200 1.00 102.52 ? 175 ASN R ND2 1 
ATOM   1362 N N   . LEU A 1 181 ? 143.667 171.945 118.020 1.00 104.61 ? 176 LEU R N   1 
ATOM   1363 C CA  . LEU A 1 181 ? 144.747 171.036 118.397 1.00 104.33 ? 176 LEU R CA  1 
ATOM   1364 C C   . LEU A 1 181 ? 145.489 171.612 119.597 1.00 104.57 ? 176 LEU R C   1 
ATOM   1365 O O   . LEU A 1 181 ? 146.045 172.713 119.520 1.00 101.72 ? 176 LEU R O   1 
ATOM   1366 C CB  . LEU A 1 181 ? 145.710 170.813 117.231 1.00 99.13  ? 176 LEU R CB  1 
ATOM   1367 C CG  . LEU A 1 181 ? 145.466 169.633 116.288 1.00 99.34  ? 176 LEU R CG  1 
ATOM   1368 C CD1 . LEU A 1 181 ? 145.795 168.323 116.985 1.00 102.72 ? 176 LEU R CD1 1 
ATOM   1369 C CD2 . LEU A 1 181 ? 144.049 169.614 115.742 1.00 99.88  ? 176 LEU R CD2 1 
ATOM   1370 N N   . CYS A 1 182 ? 145.503 170.865 120.696 1.00 104.04 ? 177 CYS R N   1 
ATOM   1371 C CA  . CYS A 1 182 ? 146.268 171.202 121.894 1.00 100.49 ? 177 CYS R CA  1 
ATOM   1372 C C   . CYS A 1 182 ? 147.191 170.020 122.185 1.00 108.68 ? 177 CYS R C   1 
ATOM   1373 O O   . CYS A 1 182 ? 146.828 169.095 122.913 1.00 111.64 ? 177 CYS R O   1 
ATOM   1374 C CB  . CYS A 1 182 ? 145.342 171.502 123.070 1.00 100.69 ? 177 CYS R CB  1 
ATOM   1375 S SG  . CYS A 1 182 ? 146.167 171.624 124.671 1.00 114.73 ? 177 CYS R SG  1 
ATOM   1376 N N   . SER A 1 183 ? 148.389 170.053 121.603 1.00 105.39 ? 178 SER R N   1 
ATOM   1377 C CA  . SER A 1 183 ? 149.319 168.939 121.740 1.00 101.80 ? 178 SER R CA  1 
ATOM   1378 C C   . SER A 1 183 ? 150.733 169.420 121.461 1.00 98.52  ? 178 SER R C   1 
ATOM   1379 O O   . SER A 1 183 ? 150.964 170.134 120.481 1.00 98.64  ? 178 SER R O   1 
ATOM   1380 C CB  . SER A 1 183 ? 148.947 167.800 120.788 1.00 99.36  ? 178 SER R CB  1 
ATOM   1381 O OG  . SER A 1 183 ? 149.029 168.218 119.437 1.00 100.02 ? 178 SER R OG  1 
ATOM   1382 N N   . SER A 1 184 ? 151.672 169.024 122.318 1.00 83.50  ? 179 SER R N   1 
ATOM   1383 C CA  . SER A 1 184 ? 153.081 169.334 122.121 1.00 81.86  ? 179 SER R CA  1 
ATOM   1384 C C   . SER A 1 184 ? 153.814 168.272 121.314 1.00 85.20  ? 179 SER R C   1 
ATOM   1385 O O   . SER A 1 184 ? 154.984 168.474 120.972 1.00 87.54  ? 179 SER R O   1 
ATOM   1386 C CB  . SER A 1 184 ? 153.779 169.512 123.472 1.00 83.80  ? 179 SER R CB  1 
ATOM   1387 O OG  . SER A 1 184 ? 153.788 168.299 124.201 1.00 85.94  ? 179 SER R OG  1 
ATOM   1388 N N   . PHE A 1 185 ? 153.161 167.156 121.005 1.00 81.82  ? 180 PHE R N   1 
ATOM   1389 C CA  . PHE A 1 185 ? 153.746 166.093 120.191 1.00 77.99  ? 180 PHE R CA  1 
ATOM   1390 C C   . PHE A 1 185 ? 153.225 166.249 118.767 1.00 81.11  ? 180 PHE R C   1 
ATOM   1391 O O   . PHE A 1 185 ? 152.281 165.576 118.352 1.00 86.59  ? 180 PHE R O   1 
ATOM   1392 C CB  . PHE A 1 185 ? 153.412 164.720 120.761 1.00 77.88  ? 180 PHE R CB  1 
ATOM   1393 C CG  . PHE A 1 185 ? 154.194 164.366 121.988 1.00 76.93  ? 180 PHE R CG  1 
ATOM   1394 C CD1 . PHE A 1 185 ? 155.534 164.690 122.086 1.00 80.68  ? 180 PHE R CD1 1 
ATOM   1395 C CD2 . PHE A 1 185 ? 153.594 163.699 123.039 1.00 78.86  ? 180 PHE R CD2 1 
ATOM   1396 C CE1 . PHE A 1 185 ? 156.258 164.360 123.211 1.00 82.54  ? 180 PHE R CE1 1 
ATOM   1397 C CE2 . PHE A 1 185 ? 154.310 163.369 124.166 1.00 79.72  ? 180 PHE R CE2 1 
ATOM   1398 C CZ  . PHE A 1 185 ? 155.645 163.700 124.253 1.00 82.21  ? 180 PHE R CZ  1 
ATOM   1399 N N   . SER A 1 186 ? 153.848 167.150 118.015 1.00 67.85  ? 181 SER R N   1 
ATOM   1400 C CA  . SER A 1 186 ? 153.575 167.320 116.596 1.00 67.18  ? 181 SER R CA  1 
ATOM   1401 C C   . SER A 1 186 ? 154.877 167.129 115.836 1.00 68.77  ? 181 SER R C   1 
ATOM   1402 O O   . SER A 1 186 ? 155.924 167.626 116.261 1.00 76.93  ? 181 SER R O   1 
ATOM   1403 C CB  . SER A 1 186 ? 152.976 168.696 116.303 1.00 65.39  ? 181 SER R CB  1 
ATOM   1404 O OG  . SER A 1 186 ? 152.041 169.064 117.300 1.00 68.15  ? 181 SER R OG  1 
ATOM   1405 N N   . ILE A 1 187 ? 154.813 166.411 114.718 1.00 61.17  ? 182 ILE R N   1 
ATOM   1406 C CA  . ILE A 1 187 ? 156.025 166.056 113.989 1.00 65.55  ? 182 ILE R CA  1 
ATOM   1407 C C   . ILE A 1 187 ? 156.550 167.312 113.305 1.00 71.07  ? 182 ILE R C   1 
ATOM   1408 O O   . ILE A 1 187 ? 156.047 167.710 112.252 1.00 80.03  ? 182 ILE R O   1 
ATOM   1409 C CB  . ILE A 1 187 ? 155.765 164.940 112.973 1.00 69.41  ? 182 ILE R CB  1 
ATOM   1410 C CG1 . ILE A 1 187 ? 154.863 163.865 113.578 1.00 68.28  ? 182 ILE R CG1 1 
ATOM   1411 C CG2 . ILE A 1 187 ? 157.078 164.330 112.522 1.00 77.48  ? 182 ILE R CG2 1 
ATOM   1412 C CD1 . ILE A 1 187 ? 153.431 163.933 113.113 1.00 65.88  ? 182 ILE R CD1 1 
ATOM   1413 N N   . CYS A 1 188 ? 157.581 167.922 113.881 1.00 81.96  ? 183 CYS R N   1 
ATOM   1414 C CA  . CYS A 1 188 ? 158.103 169.188 113.394 1.00 83.38  ? 183 CYS R CA  1 
ATOM   1415 C C   . CYS A 1 188 ? 159.604 169.075 113.169 1.00 84.01  ? 183 CYS R C   1 
ATOM   1416 O O   . CYS A 1 188 ? 160.287 168.269 113.806 1.00 86.55  ? 183 CYS R O   1 
ATOM   1417 C CB  . CYS A 1 188 ? 157.780 170.325 114.369 1.00 88.28  ? 183 CYS R CB  1 
ATOM   1418 S SG  . CYS A 1 188 ? 156.000 170.522 114.690 1.00 107.20 ? 183 CYS R SG  1 
ATOM   1419 N N   . HIS A 1 189 ? 160.110 169.905 112.253 1.00 102.17 ? 184 HIS R N   1 
ATOM   1420 C CA  . HIS A 1 189 ? 161.454 169.709 111.716 1.00 106.26 ? 184 HIS R CA  1 
ATOM   1421 C C   . HIS A 1 189 ? 162.527 169.914 112.779 1.00 107.57 ? 184 HIS R C   1 
ATOM   1422 O O   . HIS A 1 189 ? 163.413 169.068 112.949 1.00 109.23 ? 184 HIS R O   1 
ATOM   1423 C CB  . HIS A 1 189 ? 161.680 170.653 110.535 1.00 106.08 ? 184 HIS R CB  1 
ATOM   1424 C CG  . HIS A 1 189 ? 162.815 170.250 109.647 1.00 106.73 ? 184 HIS R CG  1 
ATOM   1425 N ND1 . HIS A 1 189 ? 162.799 169.093 108.898 1.00 105.41 ? 184 HIS R ND1 1 
ATOM   1426 C CD2 . HIS A 1 189 ? 163.999 170.851 109.383 1.00 107.90 ? 184 HIS R CD2 1 
ATOM   1427 C CE1 . HIS A 1 189 ? 163.924 168.997 108.213 1.00 104.11 ? 184 HIS R CE1 1 
ATOM   1428 N NE2 . HIS A 1 189 ? 164.670 170.051 108.489 1.00 107.68 ? 184 HIS R NE2 1 
ATOM   1429 N N   . THR A 1 190 ? 162.468 171.025 113.506 1.00 112.03 ? 185 THR R N   1 
ATOM   1430 C CA  . THR A 1 190 ? 163.504 171.392 114.463 1.00 112.37 ? 185 THR R CA  1 
ATOM   1431 C C   . THR A 1 190 ? 163.052 170.999 115.862 1.00 113.48 ? 185 THR R C   1 
ATOM   1432 O O   . THR A 1 190 ? 162.041 171.507 116.357 1.00 114.93 ? 185 THR R O   1 
ATOM   1433 C CB  . THR A 1 190 ? 163.808 172.888 114.399 1.00 114.43 ? 185 THR R CB  1 
ATOM   1434 O OG1 . THR A 1 190 ? 164.322 173.217 113.102 1.00 116.16 ? 185 THR R OG1 1 
ATOM   1435 C CG2 . THR A 1 190 ? 164.836 173.267 115.455 1.00 113.20 ? 185 THR R CG2 1 
ATOM   1436 N N   . PHE A 1 191 ? 163.804 170.103 116.494 1.00 121.41 ? 186 PHE R N   1 
ATOM   1437 C CA  . PHE A 1 191 ? 163.440 169.611 117.813 1.00 121.97 ? 186 PHE R CA  1 
ATOM   1438 C C   . PHE A 1 191 ? 163.649 170.689 118.872 1.00 119.18 ? 186 PHE R C   1 
ATOM   1439 O O   . PHE A 1 191 ? 164.380 171.663 118.678 1.00 119.30 ? 186 PHE R O   1 
ATOM   1440 C CB  . PHE A 1 191 ? 164.253 168.369 118.171 1.00 121.57 ? 186 PHE R CB  1 
ATOM   1441 C CG  . PHE A 1 191 ? 164.489 167.444 117.014 1.00 125.06 ? 186 PHE R CG  1 
ATOM   1442 C CD1 . PHE A 1 191 ? 163.424 166.870 116.341 1.00 125.55 ? 186 PHE R CD1 1 
ATOM   1443 C CD2 . PHE A 1 191 ? 165.777 167.143 116.604 1.00 124.56 ? 186 PHE R CD2 1 
ATOM   1444 C CE1 . PHE A 1 191 ? 163.640 166.018 115.276 1.00 123.86 ? 186 PHE R CE1 1 
ATOM   1445 C CE2 . PHE A 1 191 ? 165.999 166.291 115.540 1.00 122.88 ? 186 PHE R CE2 1 
ATOM   1446 C CZ  . PHE A 1 191 ? 164.929 165.726 114.877 1.00 121.47 ? 186 PHE R CZ  1 
ATOM   1447 N N   . GLN A 1 192 ? 162.988 170.498 120.008 1.00 115.10 ? 187 GLN R N   1 
ATOM   1448 C CA  . GLN A 1 192 ? 163.102 171.410 121.137 1.00 116.52 ? 187 GLN R CA  1 
ATOM   1449 C C   . GLN A 1 192 ? 163.501 170.596 122.366 1.00 119.05 ? 187 GLN R C   1 
ATOM   1450 O O   . GLN A 1 192 ? 163.843 169.409 122.285 1.00 118.45 ? 187 GLN R O   1 
ATOM   1451 C CB  . GLN A 1 192 ? 161.798 172.193 121.340 1.00 117.18 ? 187 GLN R CB  1 
ATOM   1452 C CG  . GLN A 1 192 ? 161.166 172.706 120.054 1.00 118.95 ? 187 GLN R CG  1 
ATOM   1453 C CD  . GLN A 1 192 ? 162.029 173.737 119.351 1.00 121.92 ? 187 GLN R CD  1 
ATOM   1454 O OE1 . GLN A 1 192 ? 162.761 174.492 119.990 1.00 122.71 ? 187 GLN R OE1 1 
ATOM   1455 N NE2 . GLN A 1 192 ? 161.947 173.772 118.026 1.00 121.41 ? 187 GLN R NE2 1 
ATOM   1456 N N   . TRP A 1 193 ? 163.458 171.240 123.533 1.00 115.06 ? 188 TRP R N   1 
ATOM   1457 C CA  . TRP A 1 193 ? 163.901 170.591 124.762 1.00 112.75 ? 188 TRP R CA  1 
ATOM   1458 C C   . TRP A 1 193 ? 162.934 169.496 125.199 1.00 107.82 ? 188 TRP R C   1 
ATOM   1459 O O   . TRP A 1 193 ? 163.277 168.651 126.035 1.00 111.96 ? 188 TRP R O   1 
ATOM   1460 C CB  . TRP A 1 193 ? 164.072 171.643 125.859 1.00 112.86 ? 188 TRP R CB  1 
ATOM   1461 C CG  . TRP A 1 193 ? 164.426 171.091 127.201 1.00 117.44 ? 188 TRP R CG  1 
ATOM   1462 C CD1 . TRP A 1 193 ? 163.621 171.034 128.301 1.00 115.81 ? 188 TRP R CD1 1 
ATOM   1463 C CD2 . TRP A 1 193 ? 165.675 170.508 127.586 1.00 119.53 ? 188 TRP R CD2 1 
ATOM   1464 N NE1 . TRP A 1 193 ? 164.295 170.460 129.350 1.00 113.47 ? 188 TRP R NE1 1 
ATOM   1465 C CE2 . TRP A 1 193 ? 165.557 170.125 128.937 1.00 116.81 ? 188 TRP R CE2 1 
ATOM   1466 C CE3 . TRP A 1 193 ? 166.883 170.275 126.922 1.00 117.59 ? 188 TRP R CE3 1 
ATOM   1467 C CZ2 . TRP A 1 193 ? 166.601 169.521 129.635 1.00 114.59 ? 188 TRP R CZ2 1 
ATOM   1468 C CZ3 . TRP A 1 193 ? 167.917 169.676 127.617 1.00 116.18 ? 188 TRP R CZ3 1 
ATOM   1469 C CH2 . TRP A 1 193 ? 167.770 169.306 128.959 1.00 114.93 ? 188 TRP R CH2 1 
ATOM   1470 N N   . HIS A 1 194 ? 161.723 169.487 124.640 1.00 74.49  ? 189 HIS R N   1 
ATOM   1471 C CA  . HIS A 1 194 ? 160.706 168.542 125.090 1.00 82.71  ? 189 HIS R CA  1 
ATOM   1472 C C   . HIS A 1 194 ? 161.053 167.099 124.737 1.00 95.18  ? 189 HIS R C   1 
ATOM   1473 O O   . HIS A 1 194 ? 160.769 166.185 125.520 1.00 100.57 ? 189 HIS R O   1 
ATOM   1474 C CB  . HIS A 1 194 ? 159.349 168.919 124.495 1.00 82.38  ? 189 HIS R CB  1 
ATOM   1475 C CG  . HIS A 1 194 ? 158.209 168.113 125.034 1.00 81.88  ? 189 HIS R CG  1 
ATOM   1476 N ND1 . HIS A 1 194 ? 157.669 168.330 126.283 1.00 79.88  ? 189 HIS R ND1 1 
ATOM   1477 C CD2 . HIS A 1 194 ? 157.506 167.091 124.494 1.00 76.97  ? 189 HIS R CD2 1 
ATOM   1478 C CE1 . HIS A 1 194 ? 156.683 167.477 126.489 1.00 78.74  ? 189 HIS R CE1 1 
ATOM   1479 N NE2 . HIS A 1 194 ? 156.564 166.713 125.418 1.00 75.78  ? 189 HIS R NE2 1 
ATOM   1480 N N   . GLU A 1 195 ? 161.656 166.868 123.567 1.00 93.04  ? 190 GLU R N   1 
ATOM   1481 C CA  . GLU A 1 195 ? 161.891 165.503 123.103 1.00 90.28  ? 190 GLU R CA  1 
ATOM   1482 C C   . GLU A 1 195 ? 162.966 164.789 123.916 1.00 89.91  ? 190 GLU R C   1 
ATOM   1483 O O   . GLU A 1 195 ? 162.882 163.568 124.123 1.00 90.48  ? 190 GLU R O   1 
ATOM   1484 C CB  . GLU A 1 195 ? 162.271 165.514 121.622 1.00 92.28  ? 190 GLU R CB  1 
ATOM   1485 C CG  . GLU A 1 195 ? 161.134 165.934 120.704 1.00 93.97  ? 190 GLU R CG  1 
ATOM   1486 C CD  . GLU A 1 195 ? 160.026 164.902 120.615 1.00 90.78  ? 190 GLU R CD  1 
ATOM   1487 O OE1 . GLU A 1 195 ? 160.202 163.775 121.122 1.00 86.98  ? 190 GLU R OE1 1 
ATOM   1488 O OE2 . GLU A 1 195 ? 158.967 165.228 120.044 1.00 92.56  ? 190 GLU R OE2 1 
ATOM   1489 N N   . ALA A 1 196 ? 163.987 165.520 124.362 1.00 89.38  ? 191 ALA R N   1 
ATOM   1490 C CA  . ALA A 1 196 ? 164.939 164.946 125.300 1.00 94.87  ? 191 ALA R CA  1 
ATOM   1491 C C   . ALA A 1 196 ? 164.260 164.504 126.586 1.00 95.23  ? 191 ALA R C   1 
ATOM   1492 O O   . ALA A 1 196 ? 164.646 163.479 127.158 1.00 99.39  ? 191 ALA R O   1 
ATOM   1493 C CB  . ALA A 1 196 ? 166.050 165.950 125.609 1.00 94.67  ? 191 ALA R CB  1 
ATOM   1494 N N   . MET A 1 197 ? 163.248 165.242 127.040 1.00 78.26  ? 192 MET R N   1 
ATOM   1495 C CA  . MET A 1 197 ? 162.491 164.869 128.226 1.00 70.10  ? 192 MET R CA  1 
ATOM   1496 C C   . MET A 1 197 ? 161.649 163.622 128.017 1.00 72.74  ? 192 MET R C   1 
ATOM   1497 O O   . MET A 1 197 ? 161.122 163.079 128.993 1.00 88.41  ? 192 MET R O   1 
ATOM   1498 C CB  . MET A 1 197 ? 161.597 166.029 128.662 1.00 66.94  ? 192 MET R CB  1 
ATOM   1499 C CG  . MET A 1 197 ? 161.169 165.962 130.107 1.00 70.95  ? 192 MET R CG  1 
ATOM   1500 S SD  . MET A 1 197 ? 162.597 166.132 131.181 1.00 99.84  ? 192 MET R SD  1 
ATOM   1501 C CE  . MET A 1 197 ? 163.211 167.708 130.617 1.00 83.74  ? 192 MET R CE  1 
ATOM   1502 N N   . PHE A 1 198 ? 161.498 163.160 126.779 1.00 53.41  ? 193 PHE R N   1 
ATOM   1503 C CA  . PHE A 1 198 ? 160.820 161.903 126.520 1.00 61.34  ? 193 PHE R CA  1 
ATOM   1504 C C   . PHE A 1 198 ? 161.776 160.759 126.230 1.00 76.56  ? 193 PHE R C   1 
ATOM   1505 O O   . PHE A 1 198 ? 161.422 159.602 126.475 1.00 85.61  ? 193 PHE R O   1 
ATOM   1506 C CB  . PHE A 1 198 ? 159.847 162.051 125.344 1.00 63.61  ? 193 PHE R CB  1 
ATOM   1507 C CG  . PHE A 1 198 ? 158.855 160.940 125.244 1.00 59.22  ? 193 PHE R CG  1 
ATOM   1508 C CD1 . PHE A 1 198 ? 158.035 160.636 126.312 1.00 55.73  ? 193 PHE R CD1 1 
ATOM   1509 C CD2 . PHE A 1 198 ? 158.735 160.202 124.080 1.00 65.54  ? 193 PHE R CD2 1 
ATOM   1510 C CE1 . PHE A 1 198 ? 157.117 159.616 126.225 1.00 64.83  ? 193 PHE R CE1 1 
ATOM   1511 C CE2 . PHE A 1 198 ? 157.819 159.182 123.986 1.00 68.99  ? 193 PHE R CE2 1 
ATOM   1512 C CZ  . PHE A 1 198 ? 157.008 158.887 125.061 1.00 72.69  ? 193 PHE R CZ  1 
ATOM   1513 N N   . LEU A 1 199 ? 162.971 161.052 125.720 1.00 80.58  ? 194 LEU R N   1 
ATOM   1514 C CA  . LEU A 1 199 ? 163.973 160.016 125.489 1.00 77.82  ? 194 LEU R CA  1 
ATOM   1515 C C   . LEU A 1 199 ? 164.785 159.686 126.739 1.00 83.04  ? 194 LEU R C   1 
ATOM   1516 O O   . LEU A 1 199 ? 164.835 158.522 127.159 1.00 86.79  ? 194 LEU R O   1 
ATOM   1517 C CB  . LEU A 1 199 ? 164.907 160.432 124.348 1.00 74.18  ? 194 LEU R CB  1 
ATOM   1518 C CG  . LEU A 1 199 ? 164.289 160.374 122.950 1.00 77.91  ? 194 LEU R CG  1 
ATOM   1519 C CD1 . LEU A 1 199 ? 165.336 160.661 121.886 1.00 81.90  ? 194 LEU R CD1 1 
ATOM   1520 C CD2 . LEU A 1 199 ? 163.635 159.029 122.713 1.00 76.42  ? 194 LEU R CD2 1 
ATOM   1521 N N   . LEU A 1 200 ? 165.422 160.692 127.347 1.00 82.95  ? 195 LEU R N   1 
ATOM   1522 C CA  . LEU A 1 200 ? 166.242 160.458 128.532 1.00 81.29  ? 195 LEU R CA  1 
ATOM   1523 C C   . LEU A 1 200 ? 165.413 159.905 129.683 1.00 79.87  ? 195 LEU R C   1 
ATOM   1524 O O   . LEU A 1 200 ? 165.865 159.012 130.415 1.00 86.07  ? 195 LEU R O   1 
ATOM   1525 C CB  . LEU A 1 200 ? 166.928 161.759 128.947 1.00 78.36  ? 195 LEU R CB  1 
ATOM   1526 C CG  . LEU A 1 200 ? 167.442 161.847 130.384 1.00 84.23  ? 195 LEU R CG  1 
ATOM   1527 C CD1 . LEU A 1 200 ? 168.765 161.109 130.531 1.00 89.25  ? 195 LEU R CD1 1 
ATOM   1528 C CD2 . LEU A 1 200 ? 167.577 163.296 130.818 1.00 78.49  ? 195 LEU R CD2 1 
ATOM   1529 N N   . GLU A 1 201 ? 164.196 160.429 129.854 1.00 68.87  ? 196 GLU R N   1 
ATOM   1530 C CA  . GLU A 1 201 ? 163.345 160.044 130.974 1.00 68.69  ? 196 GLU R CA  1 
ATOM   1531 C C   . GLU A 1 201 ? 163.057 158.550 130.979 1.00 75.82  ? 196 GLU R C   1 
ATOM   1532 O O   . GLU A 1 201 ? 162.834 157.964 132.043 1.00 87.24  ? 196 GLU R O   1 
ATOM   1533 C CB  . GLU A 1 201 ? 162.046 160.848 130.924 1.00 71.31  ? 196 GLU R CB  1 
ATOM   1534 C CG  . GLU A 1 201 ? 160.890 160.269 131.706 1.00 73.56  ? 196 GLU R CG  1 
ATOM   1535 C CD  . GLU A 1 201 ? 159.560 160.455 131.003 1.00 82.09  ? 196 GLU R CD  1 
ATOM   1536 O OE1 . GLU A 1 201 ? 159.563 160.783 129.799 1.00 80.55  ? 196 GLU R OE1 1 
ATOM   1537 O OE2 . GLU A 1 201 ? 158.511 160.275 131.655 1.00 89.41  ? 196 GLU R OE2 1 
ATOM   1538 N N   . PHE A 1 202 ? 163.064 157.914 129.811 1.00 68.15  ? 197 PHE R N   1 
ATOM   1539 C CA  . PHE A 1 202 ? 162.925 156.466 129.771 1.00 69.23  ? 197 PHE R CA  1 
ATOM   1540 C C   . PHE A 1 202 ? 164.275 155.762 129.767 1.00 77.01  ? 197 PHE R C   1 
ATOM   1541 O O   . PHE A 1 202 ? 164.408 154.684 130.358 1.00 85.57  ? 197 PHE R O   1 
ATOM   1542 C CB  . PHE A 1 202 ? 162.116 156.041 128.544 1.00 62.01  ? 197 PHE R CB  1 
ATOM   1543 C CG  . PHE A 1 202 ? 162.332 154.609 128.145 1.00 64.89  ? 197 PHE R CG  1 
ATOM   1544 C CD1 . PHE A 1 202 ? 161.662 153.590 128.797 1.00 71.46  ? 197 PHE R CD1 1 
ATOM   1545 C CD2 . PHE A 1 202 ? 163.201 154.282 127.117 1.00 69.46  ? 197 PHE R CD2 1 
ATOM   1546 C CE1 . PHE A 1 202 ? 161.856 152.274 128.433 1.00 75.65  ? 197 PHE R CE1 1 
ATOM   1547 C CE2 . PHE A 1 202 ? 163.401 152.966 126.751 1.00 68.92  ? 197 PHE R CE2 1 
ATOM   1548 C CZ  . PHE A 1 202 ? 162.727 151.962 127.409 1.00 73.01  ? 197 PHE R CZ  1 
ATOM   1549 N N   . PHE A 1 203 ? 165.283 156.345 129.114 1.00 74.56  ? 198 PHE R N   1 
ATOM   1550 C CA  . PHE A 1 203 ? 166.547 155.635 128.941 1.00 71.61  ? 198 PHE R CA  1 
ATOM   1551 C C   . PHE A 1 203 ? 167.305 155.486 130.258 1.00 79.59  ? 198 PHE R C   1 
ATOM   1552 O O   . PHE A 1 203 ? 167.794 154.397 130.580 1.00 81.32  ? 198 PHE R O   1 
ATOM   1553 C CB  . PHE A 1 203 ? 167.409 156.346 127.901 1.00 70.02  ? 198 PHE R CB  1 
ATOM   1554 C CG  . PHE A 1 203 ? 167.253 155.800 126.514 1.00 74.49  ? 198 PHE R CG  1 
ATOM   1555 C CD1 . PHE A 1 203 ? 167.199 154.435 126.298 1.00 70.63  ? 198 PHE R CD1 1 
ATOM   1556 C CD2 . PHE A 1 203 ? 167.170 156.648 125.425 1.00 78.51  ? 198 PHE R CD2 1 
ATOM   1557 C CE1 . PHE A 1 203 ? 167.058 153.926 125.024 1.00 73.29  ? 198 PHE R CE1 1 
ATOM   1558 C CE2 . PHE A 1 203 ? 167.029 156.146 124.147 1.00 78.66  ? 198 PHE R CE2 1 
ATOM   1559 C CZ  . PHE A 1 203 ? 166.973 154.782 123.947 1.00 79.49  ? 198 PHE R CZ  1 
ATOM   1560 N N   . LEU A 1 204 ? 167.417 156.564 131.035 1.00 75.30  ? 199 LEU R N   1 
ATOM   1561 C CA  . LEU A 1 204 ? 168.305 156.537 132.199 1.00 71.92  ? 199 LEU R CA  1 
ATOM   1562 C C   . LEU A 1 204 ? 167.706 155.777 133.389 1.00 74.14  ? 199 LEU R C   1 
ATOM   1563 O O   . LEU A 1 204 ? 168.410 154.967 134.026 1.00 83.79  ? 199 LEU R O   1 
ATOM   1564 C CB  . LEU A 1 204 ? 168.689 157.966 132.593 1.00 66.66  ? 199 LEU R CB  1 
ATOM   1565 C CG  . LEU A 1 204 ? 169.731 158.149 133.694 1.00 75.50  ? 199 LEU R CG  1 
ATOM   1566 C CD1 . LEU A 1 204 ? 171.053 157.522 133.286 1.00 77.52  ? 199 LEU R CD1 1 
ATOM   1567 C CD2 . LEU A 1 204 ? 169.910 159.625 134.000 1.00 72.11  ? 199 LEU R CD2 1 
ATOM   1568 N N   . PRO A 1 205 ? 166.429 155.995 133.732 1.00 52.96  ? 200 PRO R N   1 
ATOM   1569 C CA  . PRO A 1 205 ? 165.818 155.144 134.761 1.00 61.01  ? 200 PRO R CA  1 
ATOM   1570 C C   . PRO A 1 205 ? 165.845 153.672 134.412 1.00 65.58  ? 200 PRO R C   1 
ATOM   1571 O O   . PRO A 1 205 ? 165.864 152.837 135.323 1.00 74.59  ? 200 PRO R O   1 
ATOM   1572 C CB  . PRO A 1 205 ? 164.386 155.682 134.847 1.00 54.12  ? 200 PRO R CB  1 
ATOM   1573 C CG  . PRO A 1 205 ? 164.536 157.101 134.519 1.00 54.14  ? 200 PRO R CG  1 
ATOM   1574 C CD  . PRO A 1 205 ? 165.550 157.133 133.411 1.00 53.29  ? 200 PRO R CD  1 
ATOM   1575 N N   . LEU A 1 206 ? 165.855 153.322 133.125 1.00 55.10  ? 201 LEU R N   1 
ATOM   1576 C CA  . LEU A 1 206 ? 166.028 151.924 132.749 1.00 54.39  ? 201 LEU R CA  1 
ATOM   1577 C C   . LEU A 1 206 ? 167.355 151.386 133.262 1.00 69.26  ? 201 LEU R C   1 
ATOM   1578 O O   . LEU A 1 206 ? 167.414 150.298 133.847 1.00 78.24  ? 201 LEU R O   1 
ATOM   1579 C CB  . LEU A 1 206 ? 165.940 151.768 131.233 1.00 55.06  ? 201 LEU R CB  1 
ATOM   1580 C CG  . LEU A 1 206 ? 165.367 150.434 130.760 1.00 68.75  ? 201 LEU R CG  1 
ATOM   1581 C CD1 . LEU A 1 206 ? 163.936 150.284 131.230 1.00 66.62  ? 201 LEU R CD1 1 
ATOM   1582 C CD2 . LEU A 1 206 ? 165.454 150.318 129.247 1.00 70.15  ? 201 LEU R CD2 1 
ATOM   1583 N N   . GLY A 1 207 ? 168.431 152.150 133.067 1.00 73.31  ? 202 GLY R N   1 
ATOM   1584 C CA  . GLY A 1 207 ? 169.726 151.722 133.567 1.00 73.89  ? 202 GLY R CA  1 
ATOM   1585 C C   . GLY A 1 207 ? 169.744 151.588 135.076 1.00 75.35  ? 202 GLY R C   1 
ATOM   1586 O O   . GLY A 1 207 ? 170.227 150.588 135.618 1.00 74.72  ? 202 GLY R O   1 
ATOM   1587 N N   . ILE A 1 208 ? 169.191 152.584 135.777 1.00 59.99  ? 203 ILE R N   1 
ATOM   1588 C CA  . ILE A 1 208 ? 169.190 152.531 137.240 1.00 51.03  ? 203 ILE R CA  1 
ATOM   1589 C C   . ILE A 1 208 ? 168.407 151.316 137.735 1.00 58.84  ? 203 ILE R C   1 
ATOM   1590 O O   . ILE A 1 208 ? 168.880 150.553 138.592 1.00 73.10  ? 203 ILE R O   1 
ATOM   1591 C CB  . ILE A 1 208 ? 168.632 153.840 137.827 1.00 46.16  ? 203 ILE R CB  1 
ATOM   1592 C CG1 . ILE A 1 208 ? 169.748 154.871 137.978 1.00 56.90  ? 203 ILE R CG1 1 
ATOM   1593 C CG2 . ILE A 1 208 ? 167.979 153.588 139.171 1.00 52.45  ? 203 ILE R CG2 1 
ATOM   1594 C CD1 . ILE A 1 208 ? 169.299 156.162 138.617 1.00 61.03  ? 203 ILE R CD1 1 
ATOM   1595 N N   . ILE A 1 209 ? 167.207 151.106 137.186 1.00 41.70  ? 204 ILE R N   1 
ATOM   1596 C CA  . ILE A 1 209 ? 166.347 150.016 137.637 1.00 40.88  ? 204 ILE R CA  1 
ATOM   1597 C C   . ILE A 1 209 ? 166.998 148.670 137.351 1.00 58.73  ? 204 ILE R C   1 
ATOM   1598 O O   . ILE A 1 209 ? 167.010 147.773 138.204 1.00 70.17  ? 204 ILE R O   1 
ATOM   1599 C CB  . ILE A 1 209 ? 164.960 150.124 136.979 1.00 37.54  ? 204 ILE R CB  1 
ATOM   1600 C CG1 . ILE A 1 209 ? 164.059 151.063 137.775 1.00 45.92  ? 204 ILE R CG1 1 
ATOM   1601 C CG2 . ILE A 1 209 ? 164.305 148.760 136.869 1.00 51.11  ? 204 ILE R CG2 1 
ATOM   1602 C CD1 . ILE A 1 209 ? 162.690 151.234 137.170 1.00 49.55  ? 204 ILE R CD1 1 
ATOM   1603 N N   . LEU A 1 210 ? 167.545 148.503 136.143 1.00 54.17  ? 205 LEU R N   1 
ATOM   1604 C CA  . LEU A 1 210 ? 168.159 147.231 135.783 1.00 59.43  ? 205 LEU R CA  1 
ATOM   1605 C C   . LEU A 1 210 ? 169.356 146.929 136.674 1.00 66.14  ? 205 LEU R C   1 
ATOM   1606 O O   . LEU A 1 210 ? 169.507 145.805 137.171 1.00 66.86  ? 205 LEU R O   1 
ATOM   1607 C CB  . LEU A 1 210 ? 168.570 147.247 134.312 1.00 58.13  ? 205 LEU R CB  1 
ATOM   1608 C CG  . LEU A 1 210 ? 167.458 146.957 133.306 1.00 61.66  ? 205 LEU R CG  1 
ATOM   1609 C CD1 . LEU A 1 210 ? 168.035 146.774 131.913 1.00 61.47  ? 205 LEU R CD1 1 
ATOM   1610 C CD2 . LEU A 1 210 ? 166.662 145.733 133.726 1.00 61.28  ? 205 LEU R CD2 1 
ATOM   1611 N N   . PHE A 1 211 ? 170.213 147.929 136.899 1.00 63.68  ? 206 PHE R N   1 
ATOM   1612 C CA  . PHE A 1 211 ? 171.369 147.741 137.768 1.00 59.61  ? 206 PHE R CA  1 
ATOM   1613 C C   . PHE A 1 211 ? 170.935 147.306 139.161 1.00 63.57  ? 206 PHE R C   1 
ATOM   1614 O O   . PHE A 1 211 ? 171.441 146.312 139.704 1.00 69.07  ? 206 PHE R O   1 
ATOM   1615 C CB  . PHE A 1 211 ? 172.168 149.043 137.829 1.00 63.27  ? 206 PHE R CB  1 
ATOM   1616 C CG  . PHE A 1 211 ? 173.365 148.992 138.730 1.00 69.82  ? 206 PHE R CG  1 
ATOM   1617 C CD1 . PHE A 1 211 ? 174.218 147.904 138.717 1.00 73.84  ? 206 PHE R CD1 1 
ATOM   1618 C CD2 . PHE A 1 211 ? 173.643 150.043 139.585 1.00 64.93  ? 206 PHE R CD2 1 
ATOM   1619 C CE1 . PHE A 1 211 ? 175.325 147.867 139.539 1.00 73.69  ? 206 PHE R CE1 1 
ATOM   1620 C CE2 . PHE A 1 211 ? 174.745 150.009 140.411 1.00 67.09  ? 206 PHE R CE2 1 
ATOM   1621 C CZ  . PHE A 1 211 ? 175.587 148.919 140.390 1.00 72.50  ? 206 PHE R CZ  1 
ATOM   1622 N N   . CYS A 1 212 ? 169.977 148.029 139.748 1.00 58.88  ? 207 CYS R N   1 
ATOM   1623 C CA  . CYS A 1 212 ? 169.567 147.735 141.117 1.00 54.49  ? 207 CYS R CA  1 
ATOM   1624 C C   . CYS A 1 212 ? 168.940 146.350 141.226 1.00 63.29  ? 207 CYS R C   1 
ATOM   1625 O O   . CYS A 1 212 ? 169.270 145.578 142.136 1.00 79.78  ? 207 CYS R O   1 
ATOM   1626 C CB  . CYS A 1 212 ? 168.602 148.810 141.612 1.00 60.81  ? 207 CYS R CB  1 
ATOM   1627 S SG  . CYS A 1 212 ? 169.386 150.409 141.916 1.00 78.61  ? 207 CYS R SG  1 
ATOM   1628 N N   . SER A 1 213 ? 168.042 146.007 140.298 1.00 47.47  ? 208 SER R N   1 
ATOM   1629 C CA  . SER A 1 213 ? 167.381 144.707 140.365 1.00 56.88  ? 208 SER R CA  1 
ATOM   1630 C C   . SER A 1 213 ? 168.372 143.565 140.169 1.00 65.71  ? 208 SER R C   1 
ATOM   1631 O O   . SER A 1 213 ? 168.320 142.556 140.890 1.00 70.94  ? 208 SER R O   1 
ATOM   1632 C CB  . SER A 1 213 ? 166.265 144.633 139.326 1.00 58.46  ? 208 SER R CB  1 
ATOM   1633 O OG  . SER A 1 213 ? 165.142 145.390 139.736 1.00 61.93  ? 208 SER R OG  1 
ATOM   1634 N N   . ALA A 1 214 ? 169.287 143.703 139.204 1.00 62.20  ? 209 ALA R N   1 
ATOM   1635 C CA  . ALA A 1 214 ? 170.270 142.653 138.971 1.00 56.92  ? 209 ALA R CA  1 
ATOM   1636 C C   . ALA A 1 214 ? 171.161 142.455 140.187 1.00 56.28  ? 209 ALA R C   1 
ATOM   1637 O O   . ALA A 1 214 ? 171.439 141.315 140.581 1.00 59.74  ? 209 ALA R O   1 
ATOM   1638 C CB  . ALA A 1 214 ? 171.109 142.984 137.737 1.00 59.25  ? 209 ALA R CB  1 
ATOM   1639 N N   . ARG A 1 215 ? 171.612 143.550 140.805 1.00 56.72  ? 210 ARG R N   1 
ATOM   1640 C CA  . ARG A 1 215 ? 172.451 143.412 141.990 1.00 57.56  ? 210 ARG R CA  1 
ATOM   1641 C C   . ARG A 1 215 ? 171.683 142.791 143.151 1.00 57.98  ? 210 ARG R C   1 
ATOM   1642 O O   . ARG A 1 215 ? 172.247 142.000 143.914 1.00 64.88  ? 210 ARG R O   1 
ATOM   1643 C CB  . ARG A 1 215 ? 173.033 144.763 142.391 1.00 63.97  ? 210 ARG R CB  1 
ATOM   1644 C CG  . ARG A 1 215 ? 174.003 145.322 141.379 1.00 66.72  ? 210 ARG R CG  1 
ATOM   1645 C CD  . ARG A 1 215 ? 175.175 144.370 141.156 1.00 66.10  ? 210 ARG R CD  1 
ATOM   1646 N NE  . ARG A 1 215 ? 175.959 144.072 142.353 1.00 67.23  ? 210 ARG R NE  1 
ATOM   1647 C CZ  . ARG A 1 215 ? 176.452 144.965 143.205 1.00 66.64  ? 210 ARG R CZ  1 
ATOM   1648 N NH1 . ARG A 1 215 ? 176.343 146.267 142.994 1.00 62.22  ? 210 ARG R NH1 1 
ATOM   1649 N NH2 . ARG A 1 215 ? 177.099 144.538 144.285 1.00 65.56  ? 210 ARG R NH2 1 
ATOM   1650 N N   . ILE A 1 216 ? 170.403 143.137 143.308 1.00 49.84  ? 211 ILE R N   1 
ATOM   1651 C CA  . ILE A 1 216 ? 169.610 142.537 144.379 1.00 43.25  ? 211 ILE R CA  1 
ATOM   1652 C C   . ILE A 1 216 ? 169.511 141.030 144.184 1.00 54.53  ? 211 ILE R C   1 
ATOM   1653 O O   . ILE A 1 216 ? 169.715 140.249 145.123 1.00 70.70  ? 211 ILE R O   1 
ATOM   1654 C CB  . ILE A 1 216 ? 168.216 143.181 144.450 1.00 40.29  ? 211 ILE R CB  1 
ATOM   1655 C CG1 . ILE A 1 216 ? 168.299 144.593 145.019 1.00 49.17  ? 211 ILE R CG1 1 
ATOM   1656 C CG2 . ILE A 1 216 ? 167.300 142.340 145.302 1.00 41.79  ? 211 ILE R CG2 1 
ATOM   1657 C CD1 . ILE A 1 216 ? 166.967 145.291 145.076 1.00 53.99  ? 211 ILE R CD1 1 
ATOM   1658 N N   . ILE A 1 217 ? 169.202 140.598 142.959 1.00 61.60  ? 212 ILE R N   1 
ATOM   1659 C CA  . ILE A 1 217 ? 169.073 139.164 142.705 1.00 58.63  ? 212 ILE R CA  1 
ATOM   1660 C C   . ILE A 1 217 ? 170.406 138.459 142.920 1.00 62.70  ? 212 ILE R C   1 
ATOM   1661 O O   . ILE A 1 217 ? 170.461 137.365 143.499 1.00 67.21  ? 212 ILE R O   1 
ATOM   1662 C CB  . ILE A 1 217 ? 168.518 138.911 141.292 1.00 60.80  ? 212 ILE R CB  1 
ATOM   1663 C CG1 . ILE A 1 217 ? 167.186 139.633 141.113 1.00 61.89  ? 212 ILE R CG1 1 
ATOM   1664 C CG2 . ILE A 1 217 ? 168.345 137.422 141.047 1.00 63.25  ? 212 ILE R CG2 1 
ATOM   1665 C CD1 . ILE A 1 217 ? 166.143 139.216 142.105 1.00 61.66  ? 212 ILE R CD1 1 
ATOM   1666 N N   . TRP A 1 218 ? 171.501 139.070 142.462 1.00 70.32  ? 213 TRP R N   1 
ATOM   1667 C CA  . TRP A 1 218 ? 172.823 138.484 142.662 1.00 68.42  ? 213 TRP R CA  1 
ATOM   1668 C C   . TRP A 1 218 ? 173.131 138.320 144.146 1.00 73.14  ? 213 TRP R C   1 
ATOM   1669 O O   . TRP A 1 218 ? 173.554 137.246 144.591 1.00 79.25  ? 213 TRP R O   1 
ATOM   1670 C CB  . TRP A 1 218 ? 173.878 139.361 141.984 1.00 74.65  ? 213 TRP R CB  1 
ATOM   1671 C CG  . TRP A 1 218 ? 175.271 138.788 141.927 1.00 77.50  ? 213 TRP R CG  1 
ATOM   1672 C CD1 . TRP A 1 218 ? 175.770 137.749 142.656 1.00 75.34  ? 213 TRP R CD1 1 
ATOM   1673 C CD2 . TRP A 1 218 ? 176.348 139.251 141.104 1.00 83.79  ? 213 TRP R CD2 1 
ATOM   1674 N NE1 . TRP A 1 218 ? 177.084 137.528 142.329 1.00 73.56  ? 213 TRP R NE1 1 
ATOM   1675 C CE2 . TRP A 1 218 ? 177.464 138.438 141.379 1.00 79.70  ? 213 TRP R CE2 1 
ATOM   1676 C CE3 . TRP A 1 218 ? 176.474 140.271 140.156 1.00 82.21  ? 213 TRP R CE3 1 
ATOM   1677 C CZ2 . TRP A 1 218 ? 178.690 138.612 140.741 1.00 77.77  ? 213 TRP R CZ2 1 
ATOM   1678 C CZ3 . TRP A 1 218 ? 177.693 140.444 139.524 1.00 75.65  ? 213 TRP R CZ3 1 
ATOM   1679 C CH2 . TRP A 1 218 ? 178.784 139.618 139.819 1.00 76.26  ? 213 TRP R CH2 1 
ATOM   1680 N N   . SER A 1 219 ? 172.912 139.376 144.934 1.00 66.15  ? 214 SER R N   1 
ATOM   1681 C CA  . SER A 1 219 ? 173.297 139.338 146.339 1.00 58.97  ? 214 SER R CA  1 
ATOM   1682 C C   . SER A 1 219 ? 172.329 138.510 147.171 1.00 58.35  ? 214 SER R C   1 
ATOM   1683 O O   . SER A 1 219 ? 172.641 138.167 148.316 1.00 66.95  ? 214 SER R O   1 
ATOM   1684 C CB  . SER A 1 219 ? 173.398 140.755 146.895 1.00 66.03  ? 214 SER R CB  1 
ATOM   1685 O OG  . SER A 1 219 ? 174.725 141.241 146.802 1.00 72.35  ? 214 SER R OG  1 
ATOM   1686 N N   . LEU A 1 220 ? 171.156 138.183 146.629 1.00 53.22  ? 215 LEU R N   1 
ATOM   1687 C CA  . LEU A 1 220 ? 170.266 137.280 147.349 1.00 47.65  ? 215 LEU R CA  1 
ATOM   1688 C C   . LEU A 1 220 ? 170.531 135.823 146.991 1.00 55.72  ? 215 LEU R C   1 
ATOM   1689 O O   . LEU A 1 220 ? 170.377 134.938 147.840 1.00 63.07  ? 215 LEU R O   1 
ATOM   1690 C CB  . LEU A 1 220 ? 168.807 137.641 147.077 1.00 53.78  ? 215 LEU R CB  1 
ATOM   1691 C CG  . LEU A 1 220 ? 168.171 138.635 148.047 1.00 56.52  ? 215 LEU R CG  1 
ATOM   1692 C CD1 . LEU A 1 220 ? 166.694 138.795 147.750 1.00 59.30  ? 215 LEU R CD1 1 
ATOM   1693 C CD2 . LEU A 1 220 ? 168.385 138.192 149.483 1.00 57.79  ? 215 LEU R CD2 1 
ATOM   1694 N N   . ARG A 1 221 ? 170.925 135.546 145.745 1.00 82.53  ? 216 ARG R N   1 
ATOM   1695 C CA  . ARG A 1 221 ? 171.257 134.173 145.377 1.00 82.97  ? 216 ARG R CA  1 
ATOM   1696 C C   . ARG A 1 221 ? 172.609 133.751 145.942 1.00 88.99  ? 216 ARG R C   1 
ATOM   1697 O O   . ARG A 1 221 ? 172.756 132.627 146.437 1.00 90.31  ? 216 ARG R O   1 
ATOM   1698 C CB  . ARG A 1 221 ? 171.243 134.012 143.857 1.00 84.85  ? 216 ARG R CB  1 
ATOM   1699 C CG  . ARG A 1 221 ? 169.851 133.922 143.253 1.00 87.29  ? 216 ARG R CG  1 
ATOM   1700 C CD  . ARG A 1 221 ? 169.915 133.788 141.740 1.00 89.07  ? 216 ARG R CD  1 
ATOM   1701 N NE  . ARG A 1 221 ? 168.591 133.655 141.146 1.00 93.53  ? 216 ARG R NE  1 
ATOM   1702 C CZ  . ARG A 1 221 ? 168.367 133.357 139.873 1.00 93.55  ? 216 ARG R CZ  1 
ATOM   1703 N NH1 . ARG A 1 221 ? 169.363 133.152 139.026 1.00 89.56  ? 216 ARG R NH1 1 
ATOM   1704 N NH2 . ARG A 1 221 ? 167.114 133.260 139.440 1.00 89.56  ? 216 ARG R NH2 1 
ATOM   1705 N N   . GLN A 1 222 ? 173.612 134.634 145.875 1.00 75.59  ? 217 GLN R N   1 
ATOM   1706 C CA  . GLN A 1 222 ? 174.947 134.282 146.352 1.00 63.55  ? 217 GLN R CA  1 
ATOM   1707 C C   . GLN A 1 222 ? 174.967 134.052 147.857 1.00 62.77  ? 217 GLN R C   1 
ATOM   1708 O O   . GLN A 1 222 ? 175.794 133.281 148.356 1.00 63.75  ? 217 GLN R O   1 
ATOM   1709 C CB  . GLN A 1 222 ? 175.944 135.376 145.969 1.00 61.66  ? 217 GLN R CB  1 
ATOM   1710 C CG  . GLN A 1 222 ? 177.390 135.060 146.317 1.00 67.51  ? 217 GLN R CG  1 
ATOM   1711 N N   . ARG A 1 223 ? 174.064 134.697 148.591 1.00 80.64  ? 218 ARG R N   1 
ATOM   1712 C CA  . ARG A 1 223 ? 174.003 134.565 150.039 1.00 83.99  ? 218 ARG R CA  1 
ATOM   1713 C C   . ARG A 1 223 ? 173.255 133.308 150.477 1.00 86.75  ? 218 ARG R C   1 
ATOM   1714 O O   . ARG A 1 223 ? 173.321 132.943 151.657 1.00 88.81  ? 218 ARG R O   1 
ATOM   1715 C CB  . ARG A 1 223 ? 173.375 135.844 150.617 1.00 81.25  ? 218 ARG R CB  1 
ATOM   1716 C CG  . ARG A 1 223 ? 172.665 135.747 151.955 1.00 79.62  ? 218 ARG R CG  1 
ATOM   1717 C CD  . ARG A 1 223 ? 172.500 137.107 152.633 1.00 81.28  ? 218 ARG R CD  1 
ATOM   1718 N NE  . ARG A 1 223 ? 173.762 137.789 152.899 1.00 85.03  ? 218 ARG R NE  1 
ATOM   1719 C CZ  . ARG A 1 223 ? 174.358 138.637 152.070 1.00 86.92  ? 218 ARG R CZ  1 
ATOM   1720 N NH1 . ARG A 1 223 ? 173.813 138.972 150.912 1.00 84.43  ? 218 ARG R NH1 1 
ATOM   1721 N NH2 . ARG A 1 223 ? 175.525 139.172 152.418 1.00 87.63  ? 218 ARG R NH2 1 
ATOM   1722 N N   . GLN A 1 224 ? 172.610 132.608 149.543 1.00 89.27  ? 219 GLN R N   1 
ATOM   1723 C CA  . GLN A 1 224 ? 171.845 131.392 149.822 1.00 86.24  ? 219 GLN R CA  1 
ATOM   1724 C C   . GLN A 1 224 ? 170.677 131.687 150.764 1.00 87.96  ? 219 GLN R C   1 
ATOM   1725 O O   . GLN A 1 224 ? 170.579 131.160 151.873 1.00 93.28  ? 219 GLN R O   1 
ATOM   1726 C CB  . GLN A 1 224 ? 172.743 130.284 150.384 1.00 86.94  ? 219 GLN R CB  1 
ATOM   1727 C CG  . GLN A 1 224 ? 173.870 129.863 149.463 1.00 86.73  ? 219 GLN R CG  1 
ATOM   1728 C CD  . GLN A 1 224 ? 174.796 128.856 150.111 1.00 91.30  ? 219 GLN R CD  1 
ATOM   1729 O OE1 . GLN A 1 224 ? 174.834 128.731 151.335 1.00 90.79  ? 219 GLN R OE1 1 
ATOM   1730 N NE2 . GLN A 1 224 ? 175.547 128.129 149.293 1.00 95.58  ? 219 GLN R NE2 1 
ATOM   1731 N N   . MET A 1 225 ? 169.785 132.554 150.291 1.00 92.15  ? 220 MET R N   1 
ATOM   1732 C CA  . MET A 1 225 ? 168.602 132.946 151.037 1.00 91.96  ? 220 MET R CA  1 
ATOM   1733 C C   . MET A 1 225 ? 167.308 132.565 150.333 1.00 96.03  ? 220 MET R C   1 
ATOM   1734 O O   . MET A 1 225 ? 166.233 132.702 150.927 1.00 96.75  ? 220 MET R O   1 
ATOM   1735 C CB  . MET A 1 225 ? 168.624 134.459 151.291 1.00 93.04  ? 220 MET R CB  1 
ATOM   1736 C CG  . MET A 1 225 ? 169.033 134.854 152.697 1.00 94.09  ? 220 MET R CG  1 
ATOM   1737 S SD  . MET A 1 225 ? 169.036 136.640 152.937 1.00 103.70 ? 220 MET R SD  1 
ATOM   1738 C CE  . MET A 1 225 ? 167.579 136.859 153.947 1.00 93.48  ? 220 MET R CE  1 
ATOM   1739 N N   . ASP A 1 226 ? 167.380 132.070 149.095 1.00 122.99 ? 221 ASP R N   1 
ATOM   1740 C CA  . ASP A 1 226 ? 166.194 131.801 148.290 1.00 124.13 ? 221 ASP R CA  1 
ATOM   1741 C C   . ASP A 1 226 ? 165.371 130.627 148.803 1.00 122.24 ? 221 ASP R C   1 
ATOM   1742 O O   . ASP A 1 226 ? 164.264 130.408 148.299 1.00 121.32 ? 221 ASP R O   1 
ATOM   1743 C CB  . ASP A 1 226 ? 166.597 131.541 146.838 1.00 123.04 ? 221 ASP R CB  1 
ATOM   1744 C CG  . ASP A 1 226 ? 167.826 130.663 146.725 1.00 123.97 ? 221 ASP R CG  1 
ATOM   1745 O OD1 . ASP A 1 226 ? 168.412 130.323 147.774 1.00 122.09 ? 221 ASP R OD1 1 
ATOM   1746 O OD2 . ASP A 1 226 ? 168.205 130.310 145.589 1.00 125.56 ? 221 ASP R OD2 1 
ATOM   1747 N N   . ARG A 1 227 ? 165.882 129.867 149.775 1.00 112.01 ? 222 ARG R N   1 
ATOM   1748 C CA  . ARG A 1 227 ? 165.157 128.700 150.268 1.00 111.62 ? 222 ARG R CA  1 
ATOM   1749 C C   . ARG A 1 227 ? 163.789 129.086 150.818 1.00 112.19 ? 222 ARG R C   1 
ATOM   1750 O O   . ARG A 1 227 ? 162.804 128.368 150.609 1.00 113.31 ? 222 ARG R O   1 
ATOM   1751 C CB  . ARG A 1 227 ? 165.989 127.986 151.333 1.00 114.12 ? 222 ARG R CB  1 
ATOM   1752 C CG  . ARG A 1 227 ? 167.308 127.433 150.812 1.00 114.21 ? 222 ARG R CG  1 
ATOM   1753 C CD  . ARG A 1 227 ? 168.215 126.974 151.944 1.00 114.92 ? 222 ARG R CD  1 
ATOM   1754 N NE  . ARG A 1 227 ? 168.727 128.093 152.725 1.00 119.19 ? 222 ARG R NE  1 
ATOM   1755 C CZ  . ARG A 1 227 ? 169.505 127.968 153.792 1.00 115.42 ? 222 ARG R CZ  1 
ATOM   1756 N NH1 . ARG A 1 227 ? 169.882 126.780 154.237 1.00 115.10 ? 222 ARG R NH1 1 
ATOM   1757 N NH2 . ARG A 1 227 ? 169.915 129.061 154.428 1.00 110.82 ? 222 ARG R NH2 1 
ATOM   1758 N N   . HIS A 1 228 ? 163.708 130.209 151.524 1.00 118.27 ? 223 HIS R N   1 
ATOM   1759 C CA  . HIS A 1 228 ? 162.430 130.674 152.042 1.00 117.62 ? 223 HIS R CA  1 
ATOM   1760 C C   . HIS A 1 228 ? 161.534 131.137 150.898 1.00 119.03 ? 223 HIS R C   1 
ATOM   1761 O O   . HIS A 1 228 ? 162.001 131.731 149.922 1.00 120.35 ? 223 HIS R O   1 
ATOM   1762 C CB  . HIS A 1 228 ? 162.650 131.807 153.043 1.00 117.89 ? 223 HIS R CB  1 
ATOM   1763 C CG  . HIS A 1 228 ? 161.644 131.840 154.150 1.00 120.20 ? 223 HIS R CG  1 
ATOM   1764 N ND1 . HIS A 1 228 ? 160.298 131.631 153.940 1.00 121.93 ? 223 HIS R ND1 1 
ATOM   1765 C CD2 . HIS A 1 228 ? 161.789 132.053 155.479 1.00 121.08 ? 223 HIS R CD2 1 
ATOM   1766 C CE1 . HIS A 1 228 ? 159.657 131.716 155.093 1.00 121.74 ? 223 HIS R CE1 1 
ATOM   1767 N NE2 . HIS A 1 228 ? 160.539 131.972 156.042 1.00 122.08 ? 223 HIS R NE2 1 
ATOM   1768 N N   . ALA A 1 229 ? 160.234 130.857 151.022 1.00 116.65 ? 224 ALA R N   1 
ATOM   1769 C CA  . ALA A 1 229 ? 159.301 131.151 149.937 1.00 116.84 ? 224 ALA R CA  1 
ATOM   1770 C C   . ALA A 1 229 ? 159.096 132.651 149.758 1.00 118.09 ? 224 ALA R C   1 
ATOM   1771 O O   . ALA A 1 229 ? 158.934 133.133 148.627 1.00 122.98 ? 224 ALA R O   1 
ATOM   1772 C CB  . ALA A 1 229 ? 157.966 130.453 150.193 1.00 115.57 ? 224 ALA R CB  1 
ATOM   1773 N N   . LYS A 1 230 ? 159.085 133.405 150.859 1.00 107.53 ? 225 LYS R N   1 
ATOM   1774 C CA  . LYS A 1 230 ? 158.857 134.842 150.759 1.00 111.53 ? 225 LYS R CA  1 
ATOM   1775 C C   . LYS A 1 230 ? 159.939 135.523 149.933 1.00 114.27 ? 225 LYS R C   1 
ATOM   1776 O O   . LYS A 1 230 ? 159.666 136.509 149.240 1.00 113.99 ? 225 LYS R O   1 
ATOM   1777 C CB  . LYS A 1 230 ? 158.776 135.456 152.155 1.00 110.68 ? 225 LYS R CB  1 
ATOM   1778 C CG  . LYS A 1 230 ? 157.633 134.913 152.998 1.00 111.84 ? 225 LYS R CG  1 
ATOM   1779 C CD  . LYS A 1 230 ? 158.046 134.737 154.449 1.00 115.70 ? 225 LYS R CD  1 
ATOM   1780 C CE  . LYS A 1 230 ? 156.836 134.692 155.367 1.00 114.78 ? 225 LYS R CE  1 
ATOM   1781 N NZ  . LYS A 1 230 ? 156.268 136.048 155.603 1.00 112.93 ? 225 LYS R NZ  1 
ATOM   1782 N N   . ILE A 1 231 ? 161.165 135.003 149.973 1.00 111.31 ? 226 ILE R N   1 
ATOM   1783 C CA  . ILE A 1 231 ? 162.247 135.602 149.199 1.00 111.12 ? 226 ILE R CA  1 
ATOM   1784 C C   . ILE A 1 231 ? 162.053 135.346 147.708 1.00 115.75 ? 226 ILE R C   1 
ATOM   1785 O O   . ILE A 1 231 ? 162.328 136.220 146.875 1.00 116.43 ? 226 ILE R O   1 
ATOM   1786 C CB  . ILE A 1 231 ? 163.602 135.090 149.712 1.00 106.45 ? 226 ILE R CB  1 
ATOM   1787 C CG1 . ILE A 1 231 ? 163.854 135.670 151.103 1.00 109.22 ? 226 ILE R CG1 1 
ATOM   1788 C CG2 . ILE A 1 231 ? 164.721 135.466 148.756 1.00 106.68 ? 226 ILE R CG2 1 
ATOM   1789 C CD1 . ILE A 1 231 ? 165.283 135.633 151.540 1.00 110.46 ? 226 ILE R CD1 1 
ATOM   1790 N N   . LYS A 1 232 ? 161.578 134.153 147.340 1.00 116.53 ? 227 LYS R N   1 
ATOM   1791 C CA  . LYS A 1 232 ? 161.264 133.904 145.936 1.00 113.77 ? 227 LYS R CA  1 
ATOM   1792 C C   . LYS A 1 232 ? 160.106 134.783 145.474 1.00 110.91 ? 227 LYS R C   1 
ATOM   1793 O O   . LYS A 1 232 ? 160.100 135.267 144.334 1.00 112.93 ? 227 LYS R O   1 
ATOM   1794 C CB  . LYS A 1 232 ? 160.970 132.417 145.710 1.00 113.36 ? 227 LYS R CB  1 
ATOM   1795 N N   . ARG A 1 233 ? 159.130 135.027 146.356 1.00 89.71  ? 228 ARG R N   1 
ATOM   1796 C CA  . ARG A 1 233 ? 158.071 135.979 146.031 1.00 90.06  ? 228 ARG R CA  1 
ATOM   1797 C C   . ARG A 1 233 ? 158.638 137.376 145.800 1.00 100.71 ? 228 ARG R C   1 
ATOM   1798 O O   . ARG A 1 233 ? 158.227 138.082 144.867 1.00 102.11 ? 228 ARG R O   1 
ATOM   1799 C CB  . ARG A 1 233 ? 157.028 136.002 147.146 1.00 89.34  ? 228 ARG R CB  1 
ATOM   1800 C CG  . ARG A 1 233 ? 156.070 137.175 147.062 1.00 96.98  ? 228 ARG R CG  1 
ATOM   1801 C CD  . ARG A 1 233 ? 154.801 136.919 147.852 1.00 97.43  ? 228 ARG R CD  1 
ATOM   1802 N NE  . ARG A 1 233 ? 154.928 137.339 149.241 1.00 96.98  ? 228 ARG R NE  1 
ATOM   1803 C CZ  . ARG A 1 233 ? 154.369 138.429 149.747 1.00 96.55  ? 228 ARG R CZ  1 
ATOM   1804 N NH1 . ARG A 1 233 ? 153.651 139.248 148.997 1.00 95.45  ? 228 ARG R NH1 1 
ATOM   1805 N NH2 . ARG A 1 233 ? 154.536 138.707 151.036 1.00 95.80  ? 228 ARG R NH2 1 
ATOM   1806 N N   . ALA A 1 234 ? 159.582 137.793 146.646 1.00 99.51  ? 229 ALA R N   1 
ATOM   1807 C CA  . ALA A 1 234 ? 160.208 139.101 146.484 1.00 95.66  ? 229 ALA R CA  1 
ATOM   1808 C C   . ALA A 1 234 ? 160.960 139.194 145.163 1.00 94.59  ? 229 ALA R C   1 
ATOM   1809 O O   . ALA A 1 234 ? 160.907 140.224 144.480 1.00 99.07  ? 229 ALA R O   1 
ATOM   1810 C CB  . ALA A 1 234 ? 161.148 139.380 147.657 1.00 91.81  ? 229 ALA R CB  1 
ATOM   1811 N N   . ILE A 1 235 ? 161.671 138.128 144.790 1.00 79.28  ? 230 ILE R N   1 
ATOM   1812 C CA  . ILE A 1 235 ? 162.384 138.115 143.515 1.00 83.79  ? 230 ILE R CA  1 
ATOM   1813 C C   . ILE A 1 235 ? 161.402 138.241 142.356 1.00 92.32  ? 230 ILE R C   1 
ATOM   1814 O O   . ILE A 1 235 ? 161.633 138.996 141.397 1.00 95.87  ? 230 ILE R O   1 
ATOM   1815 C CB  . ILE A 1 235 ? 163.237 136.839 143.399 1.00 81.65  ? 230 ILE R CB  1 
ATOM   1816 C CG1 . ILE A 1 235 ? 164.474 136.946 144.292 1.00 85.37  ? 230 ILE R CG1 1 
ATOM   1817 C CG2 . ILE A 1 235 ? 163.624 136.582 141.953 1.00 86.30  ? 230 ILE R CG2 1 
ATOM   1818 C CD1 . ILE A 1 235 ? 165.500 135.861 144.053 1.00 88.66  ? 230 ILE R CD1 1 
ATOM   1819 N N   . THR A 1 236 ? 160.288 137.508 142.430 1.00 98.02  ? 231 THR R N   1 
ATOM   1820 C CA  . THR A 1 236 ? 159.273 137.597 141.386 1.00 94.34  ? 231 THR R CA  1 
ATOM   1821 C C   . THR A 1 236 ? 158.740 139.018 141.258 1.00 91.72  ? 231 THR R C   1 
ATOM   1822 O O   . THR A 1 236 ? 158.619 139.543 140.146 1.00 98.57  ? 231 THR R O   1 
ATOM   1823 C CB  . THR A 1 236 ? 158.131 136.625 141.676 1.00 94.37  ? 231 THR R CB  1 
ATOM   1824 O OG1 . THR A 1 236 ? 158.662 135.314 141.907 1.00 97.77  ? 231 THR R OG1 1 
ATOM   1825 C CG2 . THR A 1 236 ? 157.164 136.574 140.501 1.00 94.59  ? 231 THR R CG2 1 
ATOM   1826 N N   . PHE A 1 237 ? 158.435 139.662 142.386 1.00 76.27  ? 232 PHE R N   1 
ATOM   1827 C CA  . PHE A 1 237 ? 157.912 141.025 142.335 1.00 81.37  ? 232 PHE R CA  1 
ATOM   1828 C C   . PHE A 1 237 ? 158.943 142.001 141.779 1.00 86.37  ? 232 PHE R C   1 
ATOM   1829 O O   . PHE A 1 237 ? 158.595 142.926 141.029 1.00 92.34  ? 232 PHE R O   1 
ATOM   1830 C CB  . PHE A 1 237 ? 157.452 141.466 143.722 1.00 81.85  ? 232 PHE R CB  1 
ATOM   1831 C CG  . PHE A 1 237 ? 156.036 141.094 144.030 1.00 84.38  ? 232 PHE R CG  1 
ATOM   1832 C CD1 . PHE A 1 237 ? 155.614 139.784 143.913 1.00 85.73  ? 232 PHE R CD1 1 
ATOM   1833 C CD2 . PHE A 1 237 ? 155.122 142.055 144.416 1.00 84.78  ? 232 PHE R CD2 1 
ATOM   1834 C CE1 . PHE A 1 237 ? 154.312 139.436 144.188 1.00 87.51  ? 232 PHE R CE1 1 
ATOM   1835 C CE2 . PHE A 1 237 ? 153.817 141.713 144.689 1.00 89.40  ? 232 PHE R CE2 1 
ATOM   1836 C CZ  . PHE A 1 237 ? 153.413 140.401 144.578 1.00 89.11  ? 232 PHE R CZ  1 
ATOM   1837 N N   . ILE A 1 238 ? 160.213 141.820 142.147 1.00 73.84  ? 233 ILE R N   1 
ATOM   1838 C CA  . ILE A 1 238 ? 161.264 142.708 141.658 1.00 73.56  ? 233 ILE R CA  1 
ATOM   1839 C C   . ILE A 1 238 ? 161.386 142.603 140.144 1.00 79.52  ? 233 ILE R C   1 
ATOM   1840 O O   . ILE A 1 238 ? 161.532 143.616 139.447 1.00 87.78  ? 233 ILE R O   1 
ATOM   1841 C CB  . ILE A 1 238 ? 162.593 142.403 142.372 1.00 70.08  ? 233 ILE R CB  1 
ATOM   1842 C CG1 . ILE A 1 238 ? 162.702 143.243 143.644 1.00 74.84  ? 233 ILE R CG1 1 
ATOM   1843 C CG2 . ILE A 1 238 ? 163.779 142.654 141.455 1.00 69.63  ? 233 ILE R CG2 1 
ATOM   1844 C CD1 . ILE A 1 238 ? 163.940 142.980 144.444 1.00 75.10  ? 233 ILE R CD1 1 
ATOM   1845 N N   . MET A 1 239 ? 161.316 141.383 139.607 1.00 78.33  ? 234 MET R N   1 
ATOM   1846 C CA  . MET A 1 239 ? 161.315 141.235 138.152 1.00 79.56  ? 234 MET R CA  1 
ATOM   1847 C C   . MET A 1 239 ? 160.056 141.837 137.528 1.00 77.74  ? 234 MET R C   1 
ATOM   1848 O O   . MET A 1 239 ? 160.119 142.460 136.457 1.00 80.54  ? 234 MET R O   1 
ATOM   1849 C CB  . MET A 1 239 ? 161.458 139.760 137.775 1.00 83.18  ? 234 MET R CB  1 
ATOM   1850 C CG  . MET A 1 239 ? 162.903 139.260 137.630 1.00 81.20  ? 234 MET R CG  1 
ATOM   1851 S SD  . MET A 1 239 ? 164.151 140.219 136.719 1.00 95.96  ? 234 MET R SD  1 
ATOM   1852 C CE  . MET A 1 239 ? 163.228 141.030 135.408 1.00 86.30  ? 234 MET R CE  1 
ATOM   1853 N N   . VAL A 1 240 ? 158.908 141.664 138.189 1.00 65.36  ? 235 VAL R N   1 
ATOM   1854 C CA  . VAL A 1 240 ? 157.636 142.150 137.658 1.00 67.63  ? 235 VAL R CA  1 
ATOM   1855 C C   . VAL A 1 240 ? 157.655 143.663 137.484 1.00 72.29  ? 235 VAL R C   1 
ATOM   1856 O O   . VAL A 1 240 ? 157.140 144.193 136.491 1.00 79.78  ? 235 VAL R O   1 
ATOM   1857 C CB  . VAL A 1 240 ? 156.480 141.699 138.571 1.00 71.11  ? 235 VAL R CB  1 
ATOM   1858 C CG1 . VAL A 1 240 ? 155.249 142.549 138.340 1.00 70.11  ? 235 VAL R CG1 1 
ATOM   1859 C CG2 . VAL A 1 240 ? 156.158 140.236 138.323 1.00 72.80  ? 235 VAL R CG2 1 
ATOM   1860 N N   . VAL A 1 241 ? 158.220 144.382 138.456 1.00 67.66  ? 236 VAL R N   1 
ATOM   1861 C CA  . VAL A 1 241 ? 158.209 145.845 138.390 1.00 67.91  ? 236 VAL R CA  1 
ATOM   1862 C C   . VAL A 1 241 ? 158.924 146.329 137.131 1.00 69.39  ? 236 VAL R C   1 
ATOM   1863 O O   . VAL A 1 241 ? 158.396 147.148 136.363 1.00 78.81  ? 236 VAL R O   1 
ATOM   1864 C CB  . VAL A 1 241 ? 158.836 146.444 139.660 1.00 69.19  ? 236 VAL R CB  1 
ATOM   1865 C CG1 . VAL A 1 241 ? 159.292 147.870 139.406 1.00 72.51  ? 236 VAL R CG1 1 
ATOM   1866 C CG2 . VAL A 1 241 ? 157.846 146.393 140.809 1.00 68.66  ? 236 VAL R CG2 1 
ATOM   1867 N N   . ALA A 1 242 ? 160.131 145.812 136.893 1.00 57.84  ? 237 ALA R N   1 
ATOM   1868 C CA  . ALA A 1 242 ? 160.891 146.214 135.715 1.00 63.31  ? 237 ALA R CA  1 
ATOM   1869 C C   . ALA A 1 242 ? 160.196 145.780 134.431 1.00 68.93  ? 237 ALA R C   1 
ATOM   1870 O O   . ALA A 1 242 ? 160.212 146.515 133.434 1.00 73.03  ? 237 ALA R O   1 
ATOM   1871 C CB  . ALA A 1 242 ? 162.306 145.646 135.782 1.00 65.87  ? 237 ALA R CB  1 
ATOM   1872 N N   . ILE A 1 243 ? 159.587 144.591 134.428 1.00 72.09  ? 238 ILE R N   1 
ATOM   1873 C CA  . ILE A 1 243 ? 158.885 144.139 133.229 1.00 71.86  ? 238 ILE R CA  1 
ATOM   1874 C C   . ILE A 1 243 ? 157.744 145.089 132.887 1.00 70.87  ? 238 ILE R C   1 
ATOM   1875 O O   . ILE A 1 243 ? 157.559 145.470 131.723 1.00 73.66  ? 238 ILE R O   1 
ATOM   1876 C CB  . ILE A 1 243 ? 158.385 142.694 133.412 1.00 76.86  ? 238 ILE R CB  1 
ATOM   1877 C CG1 . ILE A 1 243 ? 159.561 141.718 133.369 1.00 76.39  ? 238 ILE R CG1 1 
ATOM   1878 C CG2 . ILE A 1 243 ? 157.364 142.342 132.346 1.00 74.16  ? 238 ILE R CG2 1 
ATOM   1879 C CD1 . ILE A 1 243 ? 160.251 141.653 132.024 1.00 72.82  ? 238 ILE R CD1 1 
ATOM   1880 N N   . VAL A 1 244 ? 156.965 145.489 133.895 1.00 64.36  ? 239 VAL R N   1 
ATOM   1881 C CA  . VAL A 1 244 ? 155.856 146.410 133.664 1.00 63.41  ? 239 VAL R CA  1 
ATOM   1882 C C   . VAL A 1 244 ? 156.371 147.744 133.144 1.00 68.28  ? 239 VAL R C   1 
ATOM   1883 O O   . VAL A 1 244 ? 155.828 148.303 132.181 1.00 71.41  ? 239 VAL R O   1 
ATOM   1884 C CB  . VAL A 1 244 ? 155.026 146.587 134.948 1.00 57.52  ? 239 VAL R CB  1 
ATOM   1885 C CG1 . VAL A 1 244 ? 154.041 147.729 134.790 1.00 64.04  ? 239 VAL R CG1 1 
ATOM   1886 C CG2 . VAL A 1 244 ? 154.296 145.305 135.283 1.00 59.53  ? 239 VAL R CG2 1 
ATOM   1887 N N   . PHE A 1 245 ? 157.434 148.269 133.760 1.00 59.65  ? 240 PHE R N   1 
ATOM   1888 C CA  . PHE A 1 245 ? 157.989 149.547 133.320 1.00 53.83  ? 240 PHE R CA  1 
ATOM   1889 C C   . PHE A 1 245 ? 158.414 149.484 131.855 1.00 64.71  ? 240 PHE R C   1 
ATOM   1890 O O   . PHE A 1 245 ? 158.093 150.382 131.060 1.00 73.02  ? 240 PHE R O   1 
ATOM   1891 C CB  . PHE A 1 245 ? 159.164 149.929 134.224 1.00 60.24  ? 240 PHE R CB  1 
ATOM   1892 C CG  . PHE A 1 245 ? 159.837 151.225 133.859 1.00 61.00  ? 240 PHE R CG  1 
ATOM   1893 C CD1 . PHE A 1 245 ? 160.800 151.277 132.868 1.00 60.27  ? 240 PHE R CD1 1 
ATOM   1894 C CD2 . PHE A 1 245 ? 159.519 152.389 134.531 1.00 62.98  ? 240 PHE R CD2 1 
ATOM   1895 C CE1 . PHE A 1 245 ? 161.418 152.464 132.548 1.00 57.67  ? 240 PHE R CE1 1 
ATOM   1896 C CE2 . PHE A 1 245 ? 160.136 153.577 134.213 1.00 62.49  ? 240 PHE R CE2 1 
ATOM   1897 C CZ  . PHE A 1 245 ? 161.086 153.614 133.221 1.00 60.67  ? 240 PHE R CZ  1 
ATOM   1898 N N   . VAL A 1 246 ? 159.129 148.421 131.478 1.00 64.36  ? 241 VAL R N   1 
ATOM   1899 C CA  . VAL A 1 246 ? 159.622 148.298 130.110 1.00 63.69  ? 241 VAL R CA  1 
ATOM   1900 C C   . VAL A 1 246 ? 158.461 148.194 129.130 1.00 66.51  ? 241 VAL R C   1 
ATOM   1901 O O   . VAL A 1 246 ? 158.399 148.923 128.130 1.00 69.40  ? 241 VAL R O   1 
ATOM   1902 C CB  . VAL A 1 246 ? 160.561 147.085 129.987 1.00 64.56  ? 241 VAL R CB  1 
ATOM   1903 C CG1 . VAL A 1 246 ? 160.640 146.617 128.542 1.00 66.06  ? 241 VAL R CG1 1 
ATOM   1904 C CG2 . VAL A 1 246 ? 161.939 147.417 130.526 1.00 67.95  ? 241 VAL R CG2 1 
ATOM   1905 N N   . ILE A 1 247 ? 157.515 147.292 129.407 1.00 70.95  ? 242 ILE R N   1 
ATOM   1906 C CA  . ILE A 1 247 ? 156.428 147.054 128.463 1.00 70.88  ? 242 ILE R CA  1 
ATOM   1907 C C   . ILE A 1 247 ? 155.492 148.250 128.400 1.00 67.01  ? 242 ILE R C   1 
ATOM   1908 O O   . ILE A 1 247 ? 154.707 148.383 127.453 1.00 69.42  ? 242 ILE R O   1 
ATOM   1909 C CB  . ILE A 1 247 ? 155.674 145.760 128.826 1.00 74.39  ? 242 ILE R CB  1 
ATOM   1910 C CG1 . ILE A 1 247 ? 155.055 145.139 127.573 1.00 73.60  ? 242 ILE R CG1 1 
ATOM   1911 C CG2 . ILE A 1 247 ? 154.606 146.031 129.875 1.00 71.20  ? 242 ILE R CG2 1 
ATOM   1912 C CD1 . ILE A 1 247 ? 156.062 144.466 126.667 1.00 71.95  ? 242 ILE R CD1 1 
ATOM   1913 N N   . CYS A 1 248 ? 155.549 149.137 129.393 1.00 72.05  ? 243 CYS R N   1 
ATOM   1914 C CA  . CYS A 1 248 ? 154.706 150.323 129.338 1.00 75.22  ? 243 CYS R CA  1 
ATOM   1915 C C   . CYS A 1 248 ? 155.371 151.464 128.578 1.00 79.44  ? 243 CYS R C   1 
ATOM   1916 O O   . CYS A 1 248 ? 154.703 152.166 127.812 1.00 85.67  ? 243 CYS R O   1 
ATOM   1917 C CB  . CYS A 1 248 ? 154.331 150.770 130.750 1.00 78.56  ? 243 CYS R CB  1 
ATOM   1918 S SG  . CYS A 1 248 ? 152.978 149.829 131.489 1.00 91.42  ? 243 CYS R SG  1 
ATOM   1919 N N   . PHE A 1 249 ? 156.675 151.674 128.766 1.00 69.07  ? 244 PHE R N   1 
ATOM   1920 C CA  . PHE A 1 249 ? 157.315 152.864 128.216 1.00 64.32  ? 244 PHE R CA  1 
ATOM   1921 C C   . PHE A 1 249 ? 158.202 152.594 127.004 1.00 68.14  ? 244 PHE R C   1 
ATOM   1922 O O   . PHE A 1 249 ? 158.872 153.518 126.534 1.00 75.84  ? 244 PHE R O   1 
ATOM   1923 C CB  . PHE A 1 249 ? 158.124 153.580 129.299 1.00 69.19  ? 244 PHE R CB  1 
ATOM   1924 C CG  . PHE A 1 249 ? 157.280 154.297 130.314 1.00 71.19  ? 244 PHE R CG  1 
ATOM   1925 C CD1 . PHE A 1 249 ? 156.466 153.592 131.182 1.00 71.53  ? 244 PHE R CD1 1 
ATOM   1926 C CD2 . PHE A 1 249 ? 157.297 155.675 130.395 1.00 69.96  ? 244 PHE R CD2 1 
ATOM   1927 C CE1 . PHE A 1 249 ? 155.692 154.249 132.114 1.00 69.40  ? 244 PHE R CE1 1 
ATOM   1928 C CE2 . PHE A 1 249 ? 156.520 156.336 131.324 1.00 70.25  ? 244 PHE R CE2 1 
ATOM   1929 C CZ  . PHE A 1 249 ? 155.720 155.621 132.185 1.00 71.49  ? 244 PHE R CZ  1 
ATOM   1930 N N   . LEU A 1 250 ? 158.235 151.370 126.482 1.00 65.15  ? 245 LEU R N   1 
ATOM   1931 C CA  . LEU A 1 250 ? 159.049 151.143 125.289 1.00 65.78  ? 245 LEU R CA  1 
ATOM   1932 C C   . LEU A 1 250 ? 158.390 151.555 123.966 1.00 70.63  ? 245 LEU R C   1 
ATOM   1933 O O   . LEU A 1 250 ? 159.040 152.237 123.154 1.00 76.58  ? 245 LEU R O   1 
ATOM   1934 C CB  . LEU A 1 250 ? 159.464 149.673 125.215 1.00 68.62  ? 245 LEU R CB  1 
ATOM   1935 C CG  . LEU A 1 250 ? 160.456 149.330 124.104 1.00 71.61  ? 245 LEU R CG  1 
ATOM   1936 C CD1 . LEU A 1 250 ? 161.744 150.115 124.280 1.00 67.96  ? 245 LEU R CD1 1 
ATOM   1937 C CD2 . LEU A 1 250 ? 160.735 147.836 124.073 1.00 69.56  ? 245 LEU R CD2 1 
ATOM   1938 N N   . PRO A 1 251 ? 157.136 151.153 123.689 1.00 68.48  ? 246 PRO R N   1 
ATOM   1939 C CA  . PRO A 1 251 ? 156.598 151.365 122.330 1.00 72.12  ? 246 PRO R CA  1 
ATOM   1940 C C   . PRO A 1 251 ? 156.566 152.818 121.887 1.00 75.27  ? 246 PRO R C   1 
ATOM   1941 O O   . PRO A 1 251 ? 156.869 153.115 120.723 1.00 80.38  ? 246 PRO R O   1 
ATOM   1942 C CB  . PRO A 1 251 ? 155.183 150.776 122.420 1.00 67.55  ? 246 PRO R CB  1 
ATOM   1943 C CG  . PRO A 1 251 ? 155.220 149.853 123.567 1.00 64.34  ? 246 PRO R CG  1 
ATOM   1944 C CD  . PRO A 1 251 ? 156.150 150.473 124.548 1.00 65.88  ? 246 PRO R CD  1 
ATOM   1945 N N   . SER A 1 252 ? 156.210 153.738 122.782 1.00 64.35  ? 247 SER R N   1 
ATOM   1946 C CA  . SER A 1 252 ? 156.186 155.144 122.403 1.00 59.30  ? 247 SER R CA  1 
ATOM   1947 C C   . SER A 1 252 ? 157.580 155.628 122.031 1.00 65.47  ? 247 SER R C   1 
ATOM   1948 O O   . SER A 1 252 ? 157.751 156.376 121.059 1.00 74.32  ? 247 SER R O   1 
ATOM   1949 C CB  . SER A 1 252 ? 155.603 155.981 123.538 1.00 71.04  ? 247 SER R CB  1 
ATOM   1950 O OG  . SER A 1 252 ? 156.327 155.781 124.740 1.00 77.87  ? 247 SER R OG  1 
ATOM   1951 N N   . VAL A 1 253 ? 158.594 155.189 122.778 1.00 47.76  ? 248 VAL R N   1 
ATOM   1952 C CA  . VAL A 1 253 ? 159.958 155.621 122.505 1.00 49.42  ? 248 VAL R CA  1 
ATOM   1953 C C   . VAL A 1 253 ? 160.439 155.074 121.167 1.00 52.88  ? 248 VAL R C   1 
ATOM   1954 O O   . VAL A 1 253 ? 161.077 155.791 120.386 1.00 66.36  ? 248 VAL R O   1 
ATOM   1955 C CB  . VAL A 1 253 ? 160.888 155.210 123.658 1.00 52.19  ? 248 VAL R CB  1 
ATOM   1956 C CG1 . VAL A 1 253 ? 162.329 155.531 123.317 1.00 60.09  ? 248 VAL R CG1 1 
ATOM   1957 C CG2 . VAL A 1 253 ? 160.475 155.913 124.936 1.00 57.31  ? 248 VAL R CG2 1 
ATOM   1958 N N   . VAL A 1 254 ? 160.137 153.808 120.867 1.00 45.52  ? 249 VAL R N   1 
ATOM   1959 C CA  . VAL A 1 254 ? 160.600 153.263 119.592 1.00 49.06  ? 249 VAL R CA  1 
ATOM   1960 C C   . VAL A 1 254 ? 159.871 153.929 118.426 1.00 65.29  ? 249 VAL R C   1 
ATOM   1961 O O   . VAL A 1 254 ? 160.471 154.201 117.377 1.00 68.46  ? 249 VAL R O   1 
ATOM   1962 C CB  . VAL A 1 254 ? 160.472 151.726 119.559 1.00 51.34  ? 249 VAL R CB  1 
ATOM   1963 C CG1 . VAL A 1 254 ? 159.037 151.279 119.673 1.00 57.06  ? 249 VAL R CG1 1 
ATOM   1964 C CG2 . VAL A 1 254 ? 161.103 151.168 118.292 1.00 55.59  ? 249 VAL R CG2 1 
ATOM   1965 N N   . VAL A 1 255 ? 158.579 154.234 118.594 1.00 74.42  ? 250 VAL R N   1 
ATOM   1966 C CA  . VAL A 1 255 ? 157.851 154.939 117.539 1.00 60.99  ? 250 VAL R CA  1 
ATOM   1967 C C   . VAL A 1 255 ? 158.448 156.323 117.314 1.00 59.54  ? 250 VAL R C   1 
ATOM   1968 O O   . VAL A 1 255 ? 158.603 156.769 116.170 1.00 64.68  ? 250 VAL R O   1 
ATOM   1969 C CB  . VAL A 1 255 ? 156.349 155.012 117.873 1.00 57.21  ? 250 VAL R CB  1 
ATOM   1970 C CG1 . VAL A 1 255 ? 155.639 155.946 116.912 1.00 61.66  ? 250 VAL R CG1 1 
ATOM   1971 C CG2 . VAL A 1 255 ? 155.722 153.632 117.813 1.00 59.95  ? 250 VAL R CG2 1 
ATOM   1972 N N   . ARG A 1 256 ? 158.786 157.030 118.395 1.00 74.79  ? 251 ARG R N   1 
ATOM   1973 C CA  . ARG A 1 256 ? 159.382 158.354 118.244 1.00 73.39  ? 251 ARG R CA  1 
ATOM   1974 C C   . ARG A 1 256 ? 160.750 158.273 117.577 1.00 68.34  ? 251 ARG R C   1 
ATOM   1975 O O   . ARG A 1 256 ? 161.123 159.155 116.793 1.00 80.19  ? 251 ARG R O   1 
ATOM   1976 C CB  . ARG A 1 256 ? 159.487 159.047 119.600 1.00 74.14  ? 251 ARG R CB  1 
ATOM   1977 C CG  . ARG A 1 256 ? 159.595 160.554 119.500 1.00 73.81  ? 251 ARG R CG  1 
ATOM   1978 C CD  . ARG A 1 256 ? 158.223 161.200 119.449 1.00 81.84  ? 251 ARG R CD  1 
ATOM   1979 N NE  . ARG A 1 256 ? 158.294 162.629 119.170 1.00 82.86  ? 251 ARG R NE  1 
ATOM   1980 C CZ  . ARG A 1 256 ? 157.394 163.298 118.463 1.00 79.08  ? 251 ARG R CZ  1 
ATOM   1981 N NH1 . ARG A 1 256 ? 156.334 162.698 117.948 1.00 79.49  ? 251 ARG R NH1 1 
ATOM   1982 N NH2 . ARG A 1 256 ? 157.562 164.602 118.269 1.00 75.41  ? 251 ARG R NH2 1 
ATOM   1983 N N   . ILE A 1 257 ? 161.517 157.227 117.884 1.00 69.82  ? 252 ILE R N   1 
ATOM   1984 C CA  . ILE A 1 257 ? 162.797 157.032 117.210 1.00 80.82  ? 252 ILE R CA  1 
ATOM   1985 C C   . ILE A 1 257 ? 162.577 156.820 115.718 1.00 84.61  ? 252 ILE R C   1 
ATOM   1986 O O   . ILE A 1 257 ? 163.328 157.334 114.882 1.00 89.33  ? 252 ILE R O   1 
ATOM   1987 C CB  . ILE A 1 257 ? 163.562 155.858 117.849 1.00 86.98  ? 252 ILE R CB  1 
ATOM   1988 C CG1 . ILE A 1 257 ? 164.131 156.276 119.206 1.00 87.49  ? 252 ILE R CG1 1 
ATOM   1989 C CG2 . ILE A 1 257 ? 164.674 155.366 116.926 1.00 83.96  ? 252 ILE R CG2 1 
ATOM   1990 C CD1 . ILE A 1 257 ? 164.328 155.122 120.164 1.00 83.57  ? 252 ILE R CD1 1 
ATOM   1991 N N   . ARG A 1 258 ? 161.539 156.063 115.363 1.00 80.32  ? 253 ARG R N   1 
ATOM   1992 C CA  . ARG A 1 258 ? 161.198 155.864 113.957 1.00 82.83  ? 253 ARG R CA  1 
ATOM   1993 C C   . ARG A 1 258 ? 160.820 157.189 113.295 1.00 85.76  ? 253 ARG R C   1 
ATOM   1994 O O   . ARG A 1 258 ? 161.194 157.458 112.142 1.00 83.10  ? 253 ARG R O   1 
ATOM   1995 C CB  . ARG A 1 258 ? 160.071 154.829 113.886 1.00 86.01  ? 253 ARG R CB  1 
ATOM   1996 C CG  . ARG A 1 258 ? 159.460 154.466 112.544 1.00 87.37  ? 253 ARG R CG  1 
ATOM   1997 C CD  . ARG A 1 258 ? 160.396 154.561 111.356 1.00 80.79  ? 253 ARG R CD  1 
ATOM   1998 N NE  . ARG A 1 258 ? 159.718 154.250 110.100 1.00 85.16  ? 253 ARG R NE  1 
ATOM   1999 C CZ  . ARG A 1 258 ? 158.629 154.853 109.634 1.00 89.21  ? 253 ARG R CZ  1 
ATOM   2000 N NH1 . ARG A 1 258 ? 158.017 155.811 110.312 1.00 88.04  ? 253 ARG R NH1 1 
ATOM   2001 N NH2 . ARG A 1 258 ? 158.136 154.479 108.456 1.00 87.40  ? 253 ARG R NH2 1 
ATOM   2002 N N   . ILE A 1 259 ? 160.087 158.034 114.024 1.00 89.30  ? 254 ILE R N   1 
ATOM   2003 C CA  . ILE A 1 259 ? 159.726 159.358 113.520 1.00 81.01  ? 254 ILE R CA  1 
ATOM   2004 C C   . ILE A 1 259 ? 160.978 160.176 113.231 1.00 75.34  ? 254 ILE R C   1 
ATOM   2005 O O   . ILE A 1 259 ? 161.106 160.795 112.168 1.00 79.71  ? 254 ILE R O   1 
ATOM   2006 C CB  . ILE A 1 259 ? 158.804 160.077 114.521 1.00 72.59  ? 254 ILE R CB  1 
ATOM   2007 C CG1 . ILE A 1 259 ? 157.354 159.647 114.317 1.00 71.30  ? 254 ILE R CG1 1 
ATOM   2008 C CG2 . ILE A 1 259 ? 158.932 161.583 114.385 1.00 74.79  ? 254 ILE R CG2 1 
ATOM   2009 C CD1 . ILE A 1 259 ? 156.737 160.187 113.050 1.00 77.15  ? 254 ILE R CD1 1 
ATOM   2010 N N   . PHE A 1 260 ? 161.925 160.183 114.171 1.00 85.28  ? 255 PHE R N   1 
ATOM   2011 C CA  . PHE A 1 260 ? 163.174 160.909 113.949 1.00 87.54  ? 255 PHE R CA  1 
ATOM   2012 C C   . PHE A 1 260 ? 163.962 160.318 112.789 1.00 89.85  ? 255 PHE R C   1 
ATOM   2013 O O   . PHE A 1 260 ? 164.641 161.053 112.058 1.00 95.66  ? 255 PHE R O   1 
ATOM   2014 C CB  . PHE A 1 260 ? 164.031 160.913 115.214 1.00 92.29  ? 255 PHE R CB  1 
ATOM   2015 C CG  . PHE A 1 260 ? 163.383 161.585 116.386 1.00 94.86  ? 255 PHE R CG  1 
ATOM   2016 C CD1 . PHE A 1 260 ? 162.783 162.823 116.243 1.00 92.33  ? 255 PHE R CD1 1 
ATOM   2017 C CD2 . PHE A 1 260 ? 163.397 160.993 117.636 1.00 93.29  ? 255 PHE R CD2 1 
ATOM   2018 C CE1 . PHE A 1 260 ? 162.192 163.449 117.319 1.00 94.02  ? 255 PHE R CE1 1 
ATOM   2019 C CE2 . PHE A 1 260 ? 162.809 161.615 118.717 1.00 91.42  ? 255 PHE R CE2 1 
ATOM   2020 C CZ  . PHE A 1 260 ? 162.205 162.845 118.559 1.00 93.27  ? 255 PHE R CZ  1 
ATOM   2021 N N   . TRP A 1 261 ? 163.891 158.998 112.613 1.00 101.42 ? 256 TRP R N   1 
ATOM   2022 C CA  . TRP A 1 261 ? 164.566 158.366 111.486 1.00 107.32 ? 256 TRP R CA  1 
ATOM   2023 C C   . TRP A 1 261 ? 164.040 158.922 110.171 1.00 109.65 ? 256 TRP R C   1 
ATOM   2024 O O   . TRP A 1 261 ? 164.817 159.378 109.319 1.00 113.44 ? 256 TRP R O   1 
ATOM   2025 C CB  . TRP A 1 261 ? 164.389 156.846 111.548 1.00 108.60 ? 256 TRP R CB  1 
ATOM   2026 C CG  . TRP A 1 261 ? 165.085 156.079 110.443 1.00 109.93 ? 256 TRP R CG  1 
ATOM   2027 C CD1 . TRP A 1 261 ? 165.941 156.577 109.501 1.00 105.76 ? 256 TRP R CD1 1 
ATOM   2028 C CD2 . TRP A 1 261 ? 164.978 154.675 110.179 1.00 111.24 ? 256 TRP R CD2 1 
ATOM   2029 N NE1 . TRP A 1 261 ? 166.368 155.573 108.668 1.00 103.12 ? 256 TRP R NE1 1 
ATOM   2030 C CE2 . TRP A 1 261 ? 165.792 154.395 109.063 1.00 106.63 ? 256 TRP R CE2 1 
ATOM   2031 C CE3 . TRP A 1 261 ? 164.271 153.627 110.776 1.00 109.20 ? 256 TRP R CE3 1 
ATOM   2032 C CZ2 . TRP A 1 261 ? 165.919 153.112 108.534 1.00 106.14 ? 256 TRP R CZ2 1 
ATOM   2033 C CZ3 . TRP A 1 261 ? 164.398 152.355 110.250 1.00 107.75 ? 256 TRP R CZ3 1 
ATOM   2034 C CH2 . TRP A 1 261 ? 165.216 152.108 109.140 1.00 108.31 ? 256 TRP R CH2 1 
ATOM   2035 N N   . LEU A 1 262 ? 162.715 158.914 109.997 1.00 91.24  ? 257 LEU R N   1 
ATOM   2036 C CA  . LEU A 1 262 ? 162.156 159.500 108.781 1.00 82.66  ? 257 LEU R CA  1 
ATOM   2037 C C   . LEU A 1 262 ? 162.511 160.974 108.670 1.00 78.84  ? 257 LEU R C   1 
ATOM   2038 O O   . LEU A 1 262 ? 162.810 161.464 107.577 1.00 77.72  ? 257 LEU R O   1 
ATOM   2039 C CB  . LEU A 1 262 ? 160.641 159.332 108.710 1.00 86.06  ? 257 LEU R CB  1 
ATOM   2040 C CG  . LEU A 1 262 ? 159.999 157.982 108.420 1.00 89.39  ? 257 LEU R CG  1 
ATOM   2041 C CD1 . LEU A 1 262 ? 158.496 158.180 108.412 1.00 92.01  ? 257 LEU R CD1 1 
ATOM   2042 C CD2 . LEU A 1 262 ? 160.476 157.418 107.093 1.00 88.70  ? 257 LEU R CD2 1 
ATOM   2043 N N   . LEU A 1 263 ? 162.498 161.694 109.793 1.00 95.97  ? 258 LEU R N   1 
ATOM   2044 C CA  . LEU A 1 263 ? 162.710 163.135 109.744 1.00 102.30 ? 258 LEU R CA  1 
ATOM   2045 C C   . LEU A 1 263 ? 164.106 163.477 109.243 1.00 98.62  ? 258 LEU R C   1 
ATOM   2046 O O   . LEU A 1 263 ? 164.273 164.419 108.459 1.00 95.57  ? 258 LEU R O   1 
ATOM   2047 C CB  . LEU A 1 263 ? 162.465 163.753 111.121 1.00 108.86 ? 258 LEU R CB  1 
ATOM   2048 C CG  . LEU A 1 263 ? 162.439 165.283 111.205 1.00 108.55 ? 258 LEU R CG  1 
ATOM   2049 C CD1 . LEU A 1 263 ? 161.386 165.733 112.202 1.00 103.66 ? 258 LEU R CD1 1 
ATOM   2050 C CD2 . LEU A 1 263 ? 163.803 165.853 111.584 1.00 104.18 ? 258 LEU R CD2 1 
ATOM   2051 N N   . HIS A 1 264 ? 165.126 162.739 109.687 1.00 104.32 ? 259 HIS R N   1 
ATOM   2052 C CA  . HIS A 1 264 ? 166.468 163.104 109.252 1.00 104.04 ? 259 HIS R CA  1 
ATOM   2053 C C   . HIS A 1 264 ? 166.902 162.368 107.991 1.00 105.31 ? 259 HIS R C   1 
ATOM   2054 O O   . HIS A 1 264 ? 167.937 162.723 107.418 1.00 103.39 ? 259 HIS R O   1 
ATOM   2055 C CB  . HIS A 1 264 ? 167.516 162.863 110.350 1.00 107.77 ? 259 HIS R CB  1 
ATOM   2056 C CG  . HIS A 1 264 ? 168.910 163.264 109.979 1.00 111.87 ? 259 HIS R CG  1 
ATOM   2057 N ND1 . HIS A 1 264 ? 169.268 164.559 109.673 1.00 112.06 ? 259 HIS R ND1 1 
ATOM   2058 C CD2 . HIS A 1 264 ? 170.041 162.527 109.878 1.00 111.41 ? 259 HIS R CD2 1 
ATOM   2059 C CE1 . HIS A 1 264 ? 170.560 164.601 109.402 1.00 108.71 ? 259 HIS R CE1 1 
ATOM   2060 N NE2 . HIS A 1 264 ? 171.052 163.381 109.513 1.00 110.56 ? 259 HIS R NE2 1 
ATOM   2061 N N   . THR A 1 265 ? 166.153 161.355 107.542 1.00 111.26 ? 260 THR R N   1 
ATOM   2062 C CA  . THR A 1 265 ? 166.468 160.693 106.279 1.00 112.10 ? 260 THR R CA  1 
ATOM   2063 C C   . THR A 1 265 ? 165.668 161.258 105.109 1.00 107.65 ? 260 THR R C   1 
ATOM   2064 O O   . THR A 1 265 ? 166.245 161.797 104.161 1.00 107.47 ? 260 THR R O   1 
ATOM   2065 C CB  . THR A 1 265 ? 166.227 159.181 106.397 1.00 115.00 ? 260 THR R CB  1 
ATOM   2066 O OG1 . THR A 1 265 ? 166.735 158.521 105.230 1.00 118.53 ? 260 THR R OG1 1 
ATOM   2067 C CG2 . THR A 1 265 ? 164.741 158.885 106.548 1.00 111.75 ? 260 THR R CG2 1 
ATOM   2068 N N   . SER A 1 266 ? 164.341 161.148 105.162 1.00 105.91 ? 261 SER R N   1 
ATOM   2069 C CA  . SER A 1 266 ? 163.505 161.587 104.050 1.00 112.08 ? 261 SER R CA  1 
ATOM   2070 C C   . SER A 1 266 ? 163.350 163.102 103.994 1.00 117.57 ? 261 SER R C   1 
ATOM   2071 O O   . SER A 1 266 ? 163.135 163.656 102.910 1.00 118.65 ? 261 SER R O   1 
ATOM   2072 C CB  . SER A 1 266 ? 162.127 160.931 104.140 1.00 111.63 ? 261 SER R CB  1 
ATOM   2073 O OG  . SER A 1 266 ? 161.498 160.889 102.871 1.00 112.37 ? 261 SER R OG  1 
ATOM   2074 N N   . GLY A 1 267 ? 163.452 163.785 105.131 1.00 124.05 ? 262 GLY R N   1 
ATOM   2075 C CA  . GLY A 1 267 ? 163.135 165.197 105.192 1.00 121.90 ? 262 GLY R CA  1 
ATOM   2076 C C   . GLY A 1 267 ? 161.654 165.433 105.412 1.00 124.46 ? 262 GLY R C   1 
ATOM   2077 O O   . GLY A 1 267 ? 160.853 164.510 105.586 1.00 123.67 ? 262 GLY R O   1 
ATOM   2078 N N   . THR A 1 268 ? 161.280 166.710 105.406 1.00 126.49 ? 263 THR R N   1 
ATOM   2079 C CA  . THR A 1 268 ? 159.898 167.128 105.638 1.00 126.08 ? 263 THR R CA  1 
ATOM   2080 C C   . THR A 1 268 ? 159.372 167.782 104.362 1.00 124.87 ? 263 THR R C   1 
ATOM   2081 O O   . THR A 1 268 ? 159.469 168.997 104.183 1.00 125.08 ? 263 THR R O   1 
ATOM   2082 C CB  . THR A 1 268 ? 159.800 168.079 106.828 1.00 124.32 ? 263 THR R CB  1 
ATOM   2083 O OG1 . THR A 1 268 ? 160.764 169.128 106.686 1.00 125.34 ? 263 THR R OG1 1 
ATOM   2084 C CG2 . THR A 1 268 ? 160.056 167.331 108.127 1.00 122.80 ? 263 THR R CG2 1 
ATOM   2085 N N   . GLN A 1 269 ? 158.818 166.966 103.475 1.00 113.24 ? 264 GLN R N   1 
ATOM   2086 C CA  . GLN A 1 269 ? 158.221 167.468 102.242 1.00 110.71 ? 264 GLN R CA  1 
ATOM   2087 C C   . GLN A 1 269 ? 156.804 166.968 102.012 1.00 104.85 ? 264 GLN R C   1 
ATOM   2088 O O   . GLN A 1 269 ? 155.963 167.729 101.527 1.00 103.64 ? 264 GLN R O   1 
ATOM   2089 C CB  . GLN A 1 269 ? 159.096 167.084 101.038 1.00 110.97 ? 264 GLN R CB  1 
ATOM   2090 C CG  . GLN A 1 269 ? 160.484 167.692 101.048 1.00 109.49 ? 264 GLN R CG  1 
ATOM   2091 C CD  . GLN A 1 269 ? 161.377 167.095 99.981  1.00 110.59 ? 264 GLN R CD  1 
ATOM   2092 O OE1 . GLN A 1 269 ? 161.006 166.126 99.318  1.00 111.02 ? 264 GLN R OE1 1 
ATOM   2093 N NE2 . GLN A 1 269 ? 162.561 167.670 99.809  1.00 111.30 ? 264 GLN R NE2 1 
ATOM   2094 N N   . ASN A 1 270 ? 156.515 165.713 102.350 1.00 82.72  ? 265 ASN R N   1 
ATOM   2095 C CA  . ASN A 1 270 ? 155.245 165.083 102.011 1.00 76.53  ? 265 ASN R CA  1 
ATOM   2096 C C   . ASN A 1 270 ? 154.698 164.385 103.246 1.00 80.58  ? 265 ASN R C   1 
ATOM   2097 O O   . ASN A 1 270 ? 155.308 163.434 103.746 1.00 88.97  ? 265 ASN R O   1 
ATOM   2098 C CB  . ASN A 1 270 ? 155.422 164.095 100.857 1.00 77.28  ? 265 ASN R CB  1 
ATOM   2099 C CG  . ASN A 1 270 ? 154.740 164.557 99.590  1.00 83.62  ? 265 ASN R CG  1 
ATOM   2100 O OD1 . ASN A 1 270 ? 154.230 165.674 99.520  1.00 86.01  ? 265 ASN R OD1 1 
ATOM   2101 N ND2 . ASN A 1 270 ? 154.734 163.703 98.576  1.00 86.26  ? 265 ASN R ND2 1 
ATOM   2102 N N   . CYS A 1 271 ? 153.544 164.850 103.728 1.00 89.38  ? 266 CYS R N   1 
ATOM   2103 C CA  . CYS A 1 271 ? 153.029 164.406 105.019 1.00 91.32  ? 266 CYS R CA  1 
ATOM   2104 C C   . CYS A 1 271 ? 152.434 163.004 104.971 1.00 95.97  ? 266 CYS R C   1 
ATOM   2105 O O   . CYS A 1 271 ? 152.418 162.316 105.999 1.00 101.03 ? 266 CYS R O   1 
ATOM   2106 C CB  . CYS A 1 271 ? 151.981 165.395 105.529 1.00 95.56  ? 266 CYS R CB  1 
ATOM   2107 S SG  . CYS A 1 271 ? 152.661 166.918 106.234 1.00 119.21 ? 266 CYS R SG  1 
ATOM   2108 N N   . GLU A 1 272 ? 151.939 162.567 103.809 1.00 88.77  ? 267 GLU R N   1 
ATOM   2109 C CA  . GLU A 1 272 ? 151.253 161.279 103.728 1.00 88.46  ? 267 GLU R CA  1 
ATOM   2110 C C   . GLU A 1 272 ? 152.147 160.130 104.181 1.00 92.65  ? 267 GLU R C   1 
ATOM   2111 O O   . GLU A 1 272 ? 151.653 159.142 104.741 1.00 82.99  ? 267 GLU R O   1 
ATOM   2112 C CB  . GLU A 1 272 ? 150.751 161.045 102.300 1.00 81.93  ? 267 GLU R CB  1 
ATOM   2113 C CG  . GLU A 1 272 ? 151.635 160.158 101.421 1.00 87.67  ? 267 GLU R CG  1 
ATOM   2114 C CD  . GLU A 1 272 ? 152.928 160.830 100.979 1.00 90.89  ? 267 GLU R CD  1 
ATOM   2115 O OE1 . GLU A 1 272 ? 153.261 161.914 101.500 1.00 89.76  ? 267 GLU R OE1 1 
ATOM   2116 O OE2 . GLU A 1 272 ? 153.621 160.266 100.106 1.00 91.14  ? 267 GLU R OE2 1 
ATOM   2117 N N   . VAL A 1 273 ? 153.464 160.261 103.986 1.00 92.48  ? 268 VAL R N   1 
ATOM   2118 C CA  . VAL A 1 273 ? 154.410 159.219 104.378 1.00 86.92  ? 268 VAL R CA  1 
ATOM   2119 C C   . VAL A 1 273 ? 154.275 158.889 105.856 1.00 82.14  ? 268 VAL R C   1 
ATOM   2120 O O   . VAL A 1 273 ? 154.590 157.772 106.286 1.00 86.83  ? 268 VAL R O   1 
ATOM   2121 C CB  . VAL A 1 273 ? 155.844 159.663 104.031 1.00 78.75  ? 268 VAL R CB  1 
ATOM   2122 C CG1 . VAL A 1 273 ? 156.830 158.526 104.245 1.00 80.43  ? 268 VAL R CG1 1 
ATOM   2123 C CG2 . VAL A 1 273 ? 155.907 160.168 102.602 1.00 76.02  ? 268 VAL R CG2 1 
ATOM   2124 N N   . TYR A 1 274 ? 153.792 159.837 106.652 1.00 55.76  ? 269 TYR R N   1 
ATOM   2125 C CA  . TYR A 1 274 ? 153.740 159.683 108.095 1.00 49.91  ? 269 TYR R CA  1 
ATOM   2126 C C   . TYR A 1 274 ? 152.420 159.100 108.577 1.00 54.11  ? 269 TYR R C   1 
ATOM   2127 O O   . TYR A 1 274 ? 152.268 158.866 109.782 1.00 62.78  ? 269 TYR R O   1 
ATOM   2128 C CB  . TYR A 1 274 ? 153.984 161.033 108.776 1.00 56.62  ? 269 TYR R CB  1 
ATOM   2129 C CG  . TYR A 1 274 ? 155.367 161.630 108.571 1.00 59.29  ? 269 TYR R CG  1 
ATOM   2130 C CD1 . TYR A 1 274 ? 156.168 161.258 107.501 1.00 56.41  ? 269 TYR R CD1 1 
ATOM   2131 C CD2 . TYR A 1 274 ? 155.864 162.578 109.451 1.00 63.02  ? 269 TYR R CD2 1 
ATOM   2132 C CE1 . TYR A 1 274 ? 157.414 161.807 107.318 1.00 62.39  ? 269 TYR R CE1 1 
ATOM   2133 C CE2 . TYR A 1 274 ? 157.112 163.131 109.273 1.00 58.32  ? 269 TYR R CE2 1 
ATOM   2134 C CZ  . TYR A 1 274 ? 157.881 162.743 108.208 1.00 60.70  ? 269 TYR R CZ  1 
ATOM   2135 O OH  . TYR A 1 274 ? 159.126 163.295 108.032 1.00 66.90  ? 269 TYR R OH  1 
ATOM   2136 N N   . ARG A 1 275 ? 151.479 158.828 107.666 1.00 74.48  ? 270 ARG R N   1 
ATOM   2137 C CA  . ARG A 1 275 ? 150.126 158.467 108.084 1.00 88.28  ? 270 ARG R CA  1 
ATOM   2138 C C   . ARG A 1 275 ? 150.124 157.241 108.988 1.00 84.92  ? 270 ARG R C   1 
ATOM   2139 O O   . ARG A 1 275 ? 149.364 157.179 109.961 1.00 82.57  ? 270 ARG R O   1 
ATOM   2140 C CB  . ARG A 1 275 ? 149.245 158.222 106.860 1.00 85.06  ? 270 ARG R CB  1 
ATOM   2141 C CG  . ARG A 1 275 ? 147.916 157.557 107.182 1.00 76.96  ? 270 ARG R CG  1 
ATOM   2142 C CD  . ARG A 1 275 ? 146.789 158.165 106.377 1.00 79.93  ? 270 ARG R CD  1 
ATOM   2143 N NE  . ARG A 1 275 ? 146.765 157.655 105.012 1.00 83.28  ? 270 ARG R NE  1 
ATOM   2144 C CZ  . ARG A 1 275 ? 146.272 158.318 103.976 1.00 85.96  ? 270 ARG R CZ  1 
ATOM   2145 N NH1 . ARG A 1 275 ? 145.758 159.529 104.112 1.00 81.35  ? 270 ARG R NH1 1 
ATOM   2146 N NH2 . ARG A 1 275 ? 146.297 157.752 102.773 1.00 83.52  ? 270 ARG R NH2 1 
ATOM   2147 N N   . SER A 1 276 ? 150.973 156.260 108.688 1.00 79.87  ? 271 SER R N   1 
ATOM   2148 C CA  . SER A 1 276 ? 150.963 155.029 109.466 1.00 78.81  ? 271 SER R CA  1 
ATOM   2149 C C   . SER A 1 276 ? 151.639 155.199 110.821 1.00 75.52  ? 271 SER R C   1 
ATOM   2150 O O   . SER A 1 276 ? 151.339 154.444 111.753 1.00 76.22  ? 271 SER R O   1 
ATOM   2151 C CB  . SER A 1 276 ? 151.630 153.905 108.676 1.00 79.06  ? 271 SER R CB  1 
ATOM   2152 O OG  . SER A 1 276 ? 150.841 153.532 107.560 1.00 74.44  ? 271 SER R OG  1 
ATOM   2153 N N   . VAL A 1 277 ? 152.542 156.167 110.964 1.00 73.29  ? 272 VAL R N   1 
ATOM   2154 C CA  . VAL A 1 277 ? 153.334 156.218 112.187 1.00 72.97  ? 272 VAL R CA  1 
ATOM   2155 C C   . VAL A 1 277 ? 152.777 157.219 113.197 1.00 74.95  ? 272 VAL R C   1 
ATOM   2156 O O   . VAL A 1 277 ? 152.864 156.985 114.407 1.00 80.70  ? 272 VAL R O   1 
ATOM   2157 C CB  . VAL A 1 277 ? 154.811 156.512 111.860 1.00 77.89  ? 272 VAL R CB  1 
ATOM   2158 C CG1 . VAL A 1 277 ? 154.938 157.659 110.874 1.00 81.14  ? 272 VAL R CG1 1 
ATOM   2159 C CG2 . VAL A 1 277 ? 155.619 156.765 113.123 1.00 78.62  ? 272 VAL R CG2 1 
ATOM   2160 N N   . ASP A 1 278 ? 152.181 158.320 112.735 1.00 76.72  ? 273 ASP R N   1 
ATOM   2161 C CA  . ASP A 1 278 ? 151.639 159.313 113.659 1.00 77.07  ? 273 ASP R CA  1 
ATOM   2162 C C   . ASP A 1 278 ? 150.507 158.730 114.497 1.00 81.44  ? 273 ASP R C   1 
ATOM   2163 O O   . ASP A 1 278 ? 150.560 158.750 115.733 1.00 85.00  ? 273 ASP R O   1 
ATOM   2164 C CB  . ASP A 1 278 ? 151.159 160.540 112.886 1.00 84.05  ? 273 ASP R CB  1 
ATOM   2165 C CG  . ASP A 1 278 ? 150.390 161.511 113.759 1.00 89.03  ? 273 ASP R CG  1 
ATOM   2166 O OD1 . ASP A 1 278 ? 151.031 162.276 114.510 1.00 85.81  ? 273 ASP R OD1 1 
ATOM   2167 O OD2 . ASP A 1 278 ? 149.143 161.510 113.694 1.00 91.53  ? 273 ASP R OD2 1 
ATOM   2168 N N   . LEU A 1 279 ? 149.482 158.187 113.833 1.00 88.64  ? 274 LEU R N   1 
ATOM   2169 C CA  . LEU A 1 279 ? 148.337 157.597 114.522 1.00 89.54  ? 274 LEU R CA  1 
ATOM   2170 C C   . LEU A 1 279 ? 148.785 156.646 115.623 1.00 94.89  ? 274 LEU R C   1 
ATOM   2171 O O   . LEU A 1 279 ? 148.508 156.866 116.810 1.00 98.63  ? 274 LEU R O   1 
ATOM   2172 C CB  . LEU A 1 279 ? 147.452 156.864 113.511 1.00 88.61  ? 274 LEU R CB  1 
ATOM   2173 C CG  . LEU A 1 279 ? 145.964 156.645 113.797 1.00 94.47  ? 274 LEU R CG  1 
ATOM   2174 C CD1 . LEU A 1 279 ? 145.272 156.166 112.535 1.00 93.75  ? 274 LEU R CD1 1 
ATOM   2175 C CD2 . LEU A 1 279 ? 145.739 155.649 114.921 1.00 91.52  ? 274 LEU R CD2 1 
ATOM   2176 N N   . ALA A 1 280 ? 149.514 155.596 115.236 1.00 82.47  ? 275 ALA R N   1 
ATOM   2177 C CA  . ALA A 1 280 ? 149.943 154.584 116.193 1.00 81.57  ? 275 ALA R CA  1 
ATOM   2178 C C   . ALA A 1 280 ? 150.667 155.213 117.372 1.00 74.10  ? 275 ALA R C   1 
ATOM   2179 O O   . ALA A 1 280 ? 150.534 154.747 118.510 1.00 73.24  ? 275 ALA R O   1 
ATOM   2180 C CB  . ALA A 1 280 ? 150.837 153.554 115.502 1.00 79.87  ? 275 ALA R CB  1 
ATOM   2181 N N   . PHE A 1 281 ? 151.410 156.297 117.122 1.00 61.16  ? 276 PHE R N   1 
ATOM   2182 C CA  . PHE A 1 281 ? 152.136 156.961 118.198 1.00 59.39  ? 276 PHE R CA  1 
ATOM   2183 C C   . PHE A 1 281 ? 151.214 157.268 119.367 1.00 59.20  ? 276 PHE R C   1 
ATOM   2184 O O   . PHE A 1 281 ? 151.490 156.877 120.508 1.00 70.85  ? 276 PHE R O   1 
ATOM   2185 C CB  . PHE A 1 281 ? 152.792 158.241 117.685 1.00 61.74  ? 276 PHE R CB  1 
ATOM   2186 C CG  . PHE A 1 281 ? 153.578 158.973 118.730 1.00 54.66  ? 276 PHE R CG  1 
ATOM   2187 C CD1 . PHE A 1 281 ? 154.755 158.449 119.222 1.00 64.58  ? 276 PHE R CD1 1 
ATOM   2188 C CD2 . PHE A 1 281 ? 153.135 160.181 119.224 1.00 54.95  ? 276 PHE R CD2 1 
ATOM   2189 C CE1 . PHE A 1 281 ? 155.474 159.117 120.184 1.00 64.43  ? 276 PHE R CE1 1 
ATOM   2190 C CE2 . PHE A 1 281 ? 153.849 160.852 120.185 1.00 58.90  ? 276 PHE R CE2 1 
ATOM   2191 C CZ  . PHE A 1 281 ? 155.020 160.321 120.665 1.00 61.60  ? 276 PHE R CZ  1 
ATOM   2192 N N   . PHE A 1 282 ? 150.077 157.910 119.090 1.00 81.89  ? 277 PHE R N   1 
ATOM   2193 C CA  . PHE A 1 282 ? 149.161 158.246 120.173 1.00 85.64  ? 277 PHE R CA  1 
ATOM   2194 C C   . PHE A 1 282 ? 148.681 156.989 120.880 1.00 92.21  ? 277 PHE R C   1 
ATOM   2195 O O   . PHE A 1 282 ? 148.636 156.941 122.116 1.00 95.46  ? 277 PHE R O   1 
ATOM   2196 C CB  . PHE A 1 282 ? 147.987 159.063 119.639 1.00 82.00  ? 277 PHE R CB  1 
ATOM   2197 C CG  . PHE A 1 282 ? 148.367 160.449 119.212 1.00 83.43  ? 277 PHE R CG  1 
ATOM   2198 C CD1 . PHE A 1 282 ? 149.040 161.289 120.078 1.00 82.97  ? 277 PHE R CD1 1 
ATOM   2199 C CD2 . PHE A 1 282 ? 148.055 160.910 117.947 1.00 89.67  ? 277 PHE R CD2 1 
ATOM   2200 C CE1 . PHE A 1 282 ? 149.399 162.564 119.692 1.00 86.99  ? 277 PHE R CE1 1 
ATOM   2201 C CE2 . PHE A 1 282 ? 148.408 162.186 117.554 1.00 92.63  ? 277 PHE R CE2 1 
ATOM   2202 C CZ  . PHE A 1 282 ? 149.082 163.014 118.430 1.00 91.27  ? 277 PHE R CZ  1 
ATOM   2203 N N   . ILE A 1 283 ? 148.374 155.940 120.113 1.00 86.00  ? 278 ILE R N   1 
ATOM   2204 C CA  . ILE A 1 283 ? 147.986 154.670 120.717 1.00 84.35  ? 278 ILE R CA  1 
ATOM   2205 C C   . ILE A 1 283 ? 149.090 154.176 121.642 1.00 82.46  ? 278 ILE R C   1 
ATOM   2206 O O   . ILE A 1 283 ? 148.838 153.794 122.791 1.00 76.68  ? 278 ILE R O   1 
ATOM   2207 C CB  . ILE A 1 283 ? 147.650 153.637 119.627 1.00 83.72  ? 278 ILE R CB  1 
ATOM   2208 C CG1 . ILE A 1 283 ? 146.207 153.818 119.155 1.00 84.14  ? 278 ILE R CG1 1 
ATOM   2209 C CG2 . ILE A 1 283 ? 147.867 152.222 120.139 1.00 82.73  ? 278 ILE R CG2 1 
ATOM   2210 C CD1 . ILE A 1 283 ? 145.709 152.705 118.264 1.00 82.23  ? 278 ILE R CD1 1 
ATOM   2211 N N   . THR A 1 284 ? 150.340 154.227 121.171 1.00 93.16  ? 279 THR R N   1 
ATOM   2212 C CA  . THR A 1 284 ? 151.451 153.813 122.019 1.00 92.15  ? 279 THR R CA  1 
ATOM   2213 C C   . THR A 1 284 ? 151.534 154.685 123.263 1.00 92.24  ? 279 THR R C   1 
ATOM   2214 O O   . THR A 1 284 ? 151.831 154.192 124.358 1.00 93.64  ? 279 THR R O   1 
ATOM   2215 C CB  . THR A 1 284 ? 152.767 153.855 121.242 1.00 91.41  ? 279 THR R CB  1 
ATOM   2216 O OG1 . THR A 1 284 ? 153.002 155.184 120.761 1.00 100.58 ? 279 THR R OG1 1 
ATOM   2217 C CG2 . THR A 1 284 ? 152.729 152.888 120.068 1.00 89.59  ? 279 THR R CG2 1 
ATOM   2218 N N   . LEU A 1 285 ? 151.244 155.981 123.121 1.00 94.68  ? 280 LEU R N   1 
ATOM   2219 C CA  . LEU A 1 285 ? 151.267 156.856 124.286 1.00 93.55  ? 280 LEU R CA  1 
ATOM   2220 C C   . LEU A 1 285 ? 150.214 156.443 125.301 1.00 93.26  ? 280 LEU R C   1 
ATOM   2221 O O   . LEU A 1 285 ? 150.427 156.596 126.510 1.00 98.77  ? 280 LEU R O   1 
ATOM   2222 C CB  . LEU A 1 285 ? 151.069 158.309 123.861 1.00 92.82  ? 280 LEU R CB  1 
ATOM   2223 C CG  . LEU A 1 285 ? 151.963 159.340 124.549 1.00 90.82  ? 280 LEU R CG  1 
ATOM   2224 C CD1 . LEU A 1 285 ? 153.334 158.762 124.848 1.00 89.57  ? 280 LEU R CD1 1 
ATOM   2225 C CD2 . LEU A 1 285 ? 152.087 160.579 123.688 1.00 93.72  ? 280 LEU R CD2 1 
ATOM   2226 N N   . SER A 1 286 ? 149.092 155.889 124.832 1.00 96.47  ? 281 SER R N   1 
ATOM   2227 C CA  . SER A 1 286 ? 148.089 155.373 125.756 1.00 104.27 ? 281 SER R CA  1 
ATOM   2228 C C   . SER A 1 286 ? 148.693 154.322 126.674 1.00 108.64 ? 281 SER R C   1 
ATOM   2229 O O   . SER A 1 286 ? 148.361 154.262 127.866 1.00 109.13 ? 281 SER R O   1 
ATOM   2230 C CB  . SER A 1 286 ? 146.904 154.798 124.979 1.00 106.03 ? 281 SER R CB  1 
ATOM   2231 O OG  . SER A 1 286 ? 147.225 153.537 124.418 1.00 107.42 ? 281 SER R OG  1 
ATOM   2232 N N   . PHE A 1 287 ? 149.611 153.507 126.141 1.00 103.44 ? 282 PHE R N   1 
ATOM   2233 C CA  . PHE A 1 287 ? 150.287 152.502 126.953 1.00 100.15 ? 282 PHE R CA  1 
ATOM   2234 C C   . PHE A 1 287 ? 150.885 153.123 128.205 1.00 98.42  ? 282 PHE R C   1 
ATOM   2235 O O   . PHE A 1 287 ? 150.803 152.544 129.297 1.00 101.95 ? 282 PHE R O   1 
ATOM   2236 C CB  . PHE A 1 287 ? 151.376 151.811 126.132 1.00 100.29 ? 282 PHE R CB  1 
ATOM   2237 C CG  . PHE A 1 287 ? 150.888 150.631 125.341 1.00 104.90 ? 282 PHE R CG  1 
ATOM   2238 C CD1 . PHE A 1 287 ? 149.532 150.391 125.192 1.00 103.74 ? 282 PHE R CD1 1 
ATOM   2239 C CD2 . PHE A 1 287 ? 151.786 149.765 124.742 1.00 102.18 ? 282 PHE R CD2 1 
ATOM   2240 C CE1 . PHE A 1 287 ? 149.083 149.306 124.463 1.00 102.79 ? 282 PHE R CE1 1 
ATOM   2241 C CE2 . PHE A 1 287 ? 151.344 148.680 124.012 1.00 101.67 ? 282 PHE R CE2 1 
ATOM   2242 C CZ  . PHE A 1 287 ? 149.990 148.449 123.872 1.00 102.37 ? 282 PHE R CZ  1 
ATOM   2243 N N   . THR A 1 288 ? 151.454 154.325 128.073 1.00 80.46  ? 283 THR R N   1 
ATOM   2244 C CA  . THR A 1 288 ? 152.070 154.980 129.220 1.00 81.19  ? 283 THR R CA  1 
ATOM   2245 C C   . THR A 1 288 ? 151.074 155.145 130.360 1.00 84.05  ? 283 THR R C   1 
ATOM   2246 O O   . THR A 1 288 ? 151.389 154.843 131.518 1.00 88.79  ? 283 THR R O   1 
ATOM   2247 C CB  . THR A 1 288 ? 152.637 156.334 128.807 1.00 82.67  ? 283 THR R CB  1 
ATOM   2248 O OG1 . THR A 1 288 ? 153.837 156.140 128.050 1.00 83.19  ? 283 THR R OG1 1 
ATOM   2249 C CG2 . THR A 1 288 ? 152.953 157.159 130.030 1.00 83.97  ? 283 THR R CG2 1 
ATOM   2250 N N   . TYR A 1 289 ? 149.853 155.585 130.046 1.00 100.12 ? 284 TYR R N   1 
ATOM   2251 C CA  . TYR A 1 289 ? 148.858 155.782 131.093 1.00 101.68 ? 284 TYR R CA  1 
ATOM   2252 C C   . TYR A 1 289 ? 148.583 154.491 131.848 1.00 102.94 ? 284 TYR R C   1 
ATOM   2253 O O   . TYR A 1 289 ? 148.327 154.523 133.059 1.00 107.40 ? 284 TYR R O   1 
ATOM   2254 C CB  . TYR A 1 289 ? 147.566 156.340 130.496 1.00 107.98 ? 284 TYR R CB  1 
ATOM   2255 C CG  . TYR A 1 289 ? 147.763 157.600 129.685 1.00 107.53 ? 284 TYR R CG  1 
ATOM   2256 C CD1 . TYR A 1 289 ? 148.680 158.563 130.078 1.00 106.20 ? 284 TYR R CD1 1 
ATOM   2257 C CD2 . TYR A 1 289 ? 147.033 157.827 128.526 1.00 106.33 ? 284 TYR R CD2 1 
ATOM   2258 C CE1 . TYR A 1 289 ? 148.867 159.712 129.341 1.00 106.50 ? 284 TYR R CE1 1 
ATOM   2259 C CE2 . TYR A 1 289 ? 147.213 158.976 127.783 1.00 105.69 ? 284 TYR R CE2 1 
ATOM   2260 C CZ  . TYR A 1 289 ? 148.132 159.915 128.196 1.00 106.55 ? 284 TYR R CZ  1 
ATOM   2261 O OH  . TYR A 1 289 ? 148.318 161.064 127.462 1.00 107.35 ? 284 TYR R OH  1 
ATOM   2262 N N   . MET A 1 290 ? 148.662 153.346 131.159 1.00 111.97 ? 285 MET R N   1 
ATOM   2263 C CA  . MET A 1 290 ? 148.440 152.064 131.820 1.00 113.62 ? 285 MET R CA  1 
ATOM   2264 C C   . MET A 1 290 ? 149.359 151.903 133.022 1.00 115.23 ? 285 MET R C   1 
ATOM   2265 O O   . MET A 1 290 ? 148.939 151.401 134.073 1.00 116.73 ? 285 MET R O   1 
ATOM   2266 C CB  . MET A 1 290 ? 148.652 150.921 130.827 1.00 112.99 ? 285 MET R CB  1 
ATOM   2267 C CG  . MET A 1 290 ? 147.452 150.010 130.659 1.00 114.52 ? 285 MET R CG  1 
ATOM   2268 S SD  . MET A 1 290 ? 147.542 149.031 129.148 1.00 120.87 ? 285 MET R SD  1 
ATOM   2269 C CE  . MET A 1 290 ? 146.724 150.123 127.988 1.00 112.52 ? 285 MET R CE  1 
ATOM   2270 N N   . ASN A 1 291 ? 150.607 152.366 132.897 1.00 111.55 ? 286 ASN R N   1 
ATOM   2271 C CA  . ASN A 1 291 ? 151.555 152.262 134.001 1.00 107.18 ? 286 ASN R CA  1 
ATOM   2272 C C   . ASN A 1 291 ? 150.960 152.813 135.287 1.00 105.08 ? 286 ASN R C   1 
ATOM   2273 O O   . ASN A 1 291 ? 151.072 152.190 136.350 1.00 109.35 ? 286 ASN R O   1 
ATOM   2274 C CB  . ASN A 1 291 ? 152.846 153.000 133.648 1.00 106.97 ? 286 ASN R CB  1 
ATOM   2275 C CG  . ASN A 1 291 ? 153.889 152.909 134.741 1.00 107.28 ? 286 ASN R CG  1 
ATOM   2276 O OD1 . ASN A 1 291 ? 153.999 153.797 135.584 1.00 108.37 ? 286 ASN R OD1 1 
ATOM   2277 N ND2 . ASN A 1 291 ? 154.666 151.833 134.729 1.00 107.22 ? 286 ASN R ND2 1 
ATOM   2278 N N   . SER A 1 292 ? 150.272 153.955 135.197 1.00 106.20 ? 287 SER R N   1 
ATOM   2279 C CA  . SER A 1 292 ? 149.677 154.551 136.387 1.00 106.67 ? 287 SER R CA  1 
ATOM   2280 C C   . SER A 1 292 ? 148.729 153.576 137.073 1.00 111.90 ? 287 SER R C   1 
ATOM   2281 O O   . SER A 1 292 ? 148.862 153.305 138.273 1.00 115.87 ? 287 SER R O   1 
ATOM   2282 C CB  . SER A 1 292 ? 148.948 155.839 136.019 1.00 109.69 ? 287 SER R CB  1 
ATOM   2283 O OG  . SER A 1 292 ? 147.840 155.575 135.175 1.00 115.46 ? 287 SER R OG  1 
ATOM   2284 N N   . MET A 1 293 ? 147.795 152.993 136.314 1.00 119.53 ? 288 MET R N   1 
ATOM   2285 C CA  . MET A 1 293 ? 146.817 152.115 136.944 1.00 118.98 ? 288 MET R CA  1 
ATOM   2286 C C   . MET A 1 293 ? 147.444 150.805 137.393 1.00 121.13 ? 288 MET R C   1 
ATOM   2287 O O   . MET A 1 293 ? 146.786 150.018 138.081 1.00 120.78 ? 288 MET R O   1 
ATOM   2288 C CB  . MET A 1 293 ? 145.633 151.852 136.008 1.00 118.74 ? 288 MET R CB  1 
ATOM   2289 C CG  . MET A 1 293 ? 145.982 151.176 134.698 1.00 120.95 ? 288 MET R CG  1 
ATOM   2290 S SD  . MET A 1 293 ? 144.711 150.022 134.149 1.00 129.16 ? 288 MET R SD  1 
ATOM   2291 C CE  . MET A 1 293 ? 144.408 149.109 135.660 1.00 121.14 ? 288 MET R CE  1 
ATOM   2292 N N   . LEU A 1 294 ? 148.701 150.552 137.020 1.00 118.20 ? 289 LEU R N   1 
ATOM   2293 C CA  . LEU A 1 294 ? 149.402 149.386 137.536 1.00 114.39 ? 289 LEU R CA  1 
ATOM   2294 C C   . LEU A 1 294 ? 150.316 149.725 138.706 1.00 113.66 ? 289 LEU R C   1 
ATOM   2295 O O   . LEU A 1 294 ? 150.796 148.808 139.380 1.00 113.43 ? 289 LEU R O   1 
ATOM   2296 C CB  . LEU A 1 294 ? 150.213 148.720 136.424 1.00 114.00 ? 289 LEU R CB  1 
ATOM   2297 C CG  . LEU A 1 294 ? 149.406 148.068 135.300 1.00 113.83 ? 289 LEU R CG  1 
ATOM   2298 C CD1 . LEU A 1 294 ? 150.296 147.772 134.105 1.00 113.58 ? 289 LEU R CD1 1 
ATOM   2299 C CD2 . LEU A 1 294 ? 148.726 146.802 135.791 1.00 112.33 ? 289 LEU R CD2 1 
ATOM   2300 N N   . ASP A 1 295 ? 150.572 151.011 138.959 1.00 113.37 ? 290 ASP R N   1 
ATOM   2301 C CA  . ASP A 1 295 ? 151.513 151.373 140.018 1.00 109.66 ? 290 ASP R CA  1 
ATOM   2302 C C   . ASP A 1 295 ? 151.049 150.939 141.403 1.00 111.72 ? 290 ASP R C   1 
ATOM   2303 O O   . ASP A 1 295 ? 151.847 150.317 142.126 1.00 115.47 ? 290 ASP R O   1 
ATOM   2304 C CB  . ASP A 1 295 ? 151.805 152.876 139.965 1.00 110.60 ? 290 ASP R CB  1 
ATOM   2305 C CG  . ASP A 1 295 ? 152.678 153.258 138.787 1.00 114.27 ? 290 ASP R CG  1 
ATOM   2306 O OD1 . ASP A 1 295 ? 153.559 152.455 138.415 1.00 110.91 ? 290 ASP R OD1 1 
ATOM   2307 O OD2 . ASP A 1 295 ? 152.484 154.361 138.235 1.00 118.41 ? 290 ASP R OD2 1 
ATOM   2308 N N   . PRO A 1 296 ? 149.815 151.216 141.845 1.00 118.33 ? 291 PRO R N   1 
ATOM   2309 C CA  . PRO A 1 296 ? 149.410 150.703 143.163 1.00 118.53 ? 291 PRO R CA  1 
ATOM   2310 C C   . PRO A 1 296 ? 149.135 149.213 143.159 1.00 115.68 ? 291 PRO R C   1 
ATOM   2311 O O   . PRO A 1 296 ? 149.409 148.544 144.164 1.00 113.11 ? 291 PRO R O   1 
ATOM   2312 C CB  . PRO A 1 296 ? 148.145 151.509 143.484 1.00 118.13 ? 291 PRO R CB  1 
ATOM   2313 C CG  . PRO A 1 296 ? 147.593 151.875 142.161 1.00 118.38 ? 291 PRO R CG  1 
ATOM   2314 C CD  . PRO A 1 296 ? 148.771 152.073 141.252 1.00 116.88 ? 291 PRO R CD  1 
ATOM   2315 N N   . VAL A 1 297 ? 148.635 148.672 142.044 1.00 117.94 ? 292 VAL R N   1 
ATOM   2316 C CA  . VAL A 1 297 ? 148.209 147.275 141.999 1.00 119.24 ? 292 VAL R CA  1 
ATOM   2317 C C   . VAL A 1 297 ? 149.352 146.352 142.395 1.00 117.73 ? 292 VAL R C   1 
ATOM   2318 O O   . VAL A 1 297 ? 149.162 145.394 143.153 1.00 118.85 ? 292 VAL R O   1 
ATOM   2319 C CB  . VAL A 1 297 ? 147.660 146.931 140.602 1.00 119.43 ? 292 VAL R CB  1 
ATOM   2320 C CG1 . VAL A 1 297 ? 147.469 145.429 140.457 1.00 116.77 ? 292 VAL R CG1 1 
ATOM   2321 C CG2 . VAL A 1 297 ? 146.353 147.666 140.351 1.00 119.35 ? 292 VAL R CG2 1 
ATOM   2322 N N   . VAL A 1 298 ? 150.556 146.622 141.893 1.00 107.87 ? 293 VAL R N   1 
ATOM   2323 C CA  . VAL A 1 298 ? 151.715 145.845 142.315 1.00 107.26 ? 293 VAL R CA  1 
ATOM   2324 C C   . VAL A 1 298 ? 152.037 146.123 143.778 1.00 108.67 ? 293 VAL R C   1 
ATOM   2325 O O   . VAL A 1 298 ? 152.170 145.198 144.590 1.00 110.70 ? 293 VAL R O   1 
ATOM   2326 C CB  . VAL A 1 298 ? 152.920 146.145 141.405 1.00 104.21 ? 293 VAL R CB  1 
ATOM   2327 C CG1 . VAL A 1 298 ? 154.184 145.532 141.980 1.00 106.14 ? 293 VAL R CG1 1 
ATOM   2328 C CG2 . VAL A 1 298 ? 152.664 145.631 140.000 1.00 105.86 ? 293 VAL R CG2 1 
ATOM   2329 N N   . TYR A 1 299 ? 152.116 147.402 144.150 1.00 99.65  ? 294 TYR R N   1 
ATOM   2330 C CA  . TYR A 1 299 ? 152.690 147.763 145.441 1.00 97.22  ? 294 TYR R CA  1 
ATOM   2331 C C   . TYR A 1 299 ? 151.728 147.566 146.603 1.00 101.07 ? 294 TYR R C   1 
ATOM   2332 O O   . TYR A 1 299 ? 152.157 147.646 147.759 1.00 97.57  ? 294 TYR R O   1 
ATOM   2333 C CB  . TYR A 1 299 ? 153.190 149.209 145.414 1.00 97.88  ? 294 TYR R CB  1 
ATOM   2334 C CG  . TYR A 1 299 ? 154.249 149.464 144.364 1.00 98.24  ? 294 TYR R CG  1 
ATOM   2335 C CD1 . TYR A 1 299 ? 155.035 148.430 143.881 1.00 97.02  ? 294 TYR R CD1 1 
ATOM   2336 C CD2 . TYR A 1 299 ? 154.469 150.739 143.865 1.00 98.37  ? 294 TYR R CD2 1 
ATOM   2337 C CE1 . TYR A 1 299 ? 156.003 148.655 142.925 1.00 98.05  ? 294 TYR R CE1 1 
ATOM   2338 C CE2 . TYR A 1 299 ? 155.437 150.973 142.908 1.00 97.97  ? 294 TYR R CE2 1 
ATOM   2339 C CZ  . TYR A 1 299 ? 156.200 149.927 142.442 1.00 96.29  ? 294 TYR R CZ  1 
ATOM   2340 O OH  . TYR A 1 299 ? 157.166 150.150 141.491 1.00 94.13  ? 294 TYR R OH  1 
ATOM   2341 N N   . TYR A 1 300 ? 150.448 147.321 146.336 1.00 128.02 ? 295 TYR R N   1 
ATOM   2342 C CA  . TYR A 1 300 ? 149.540 146.878 147.384 1.00 126.48 ? 295 TYR R CA  1 
ATOM   2343 C C   . TYR A 1 300 ? 149.361 145.367 147.396 1.00 124.52 ? 295 TYR R C   1 
ATOM   2344 O O   . TYR A 1 300 ? 148.695 144.843 148.295 1.00 122.16 ? 295 TYR R O   1 
ATOM   2345 C CB  . TYR A 1 300 ? 148.175 147.568 147.243 1.00 124.33 ? 295 TYR R CB  1 
ATOM   2346 C CG  . TYR A 1 300 ? 147.121 147.108 148.228 1.00 127.23 ? 295 TYR R CG  1 
ATOM   2347 C CD1 . TYR A 1 300 ? 147.137 147.541 149.544 1.00 127.43 ? 295 TYR R CD1 1 
ATOM   2348 C CD2 . TYR A 1 300 ? 146.120 146.225 147.841 1.00 127.57 ? 295 TYR R CD2 1 
ATOM   2349 C CE1 . TYR A 1 300 ? 146.179 147.121 150.448 1.00 126.70 ? 295 TYR R CE1 1 
ATOM   2350 C CE2 . TYR A 1 300 ? 145.157 145.799 148.737 1.00 128.71 ? 295 TYR R CE2 1 
ATOM   2351 C CZ  . TYR A 1 300 ? 145.192 146.249 150.039 1.00 127.75 ? 295 TYR R CZ  1 
ATOM   2352 O OH  . TYR A 1 300 ? 144.237 145.826 150.935 1.00 125.66 ? 295 TYR R OH  1 
ATOM   2353 N N   . PHE A 1 301 ? 149.949 144.657 146.432 1.00 122.50 ? 296 PHE R N   1 
ATOM   2354 C CA  . PHE A 1 301 ? 149.843 143.206 146.370 1.00 121.34 ? 296 PHE R CA  1 
ATOM   2355 C C   . PHE A 1 301 ? 151.020 142.497 147.028 1.00 122.62 ? 296 PHE R C   1 
ATOM   2356 O O   . PHE A 1 301 ? 150.943 141.285 147.256 1.00 121.37 ? 296 PHE R O   1 
ATOM   2357 C CB  . PHE A 1 301 ? 149.718 142.753 144.911 1.00 121.94 ? 296 PHE R CB  1 
ATOM   2358 C CG  . PHE A 1 301 ? 149.231 141.340 144.751 1.00 126.98 ? 296 PHE R CG  1 
ATOM   2359 N N   . SER A 1 302 ? 152.099 143.218 147.340 1.00 116.36 ? 297 SER R N   1 
ATOM   2360 C CA  . SER A 1 302 ? 153.248 142.589 147.983 1.00 115.65 ? 297 SER R CA  1 
ATOM   2361 C C   . SER A 1 302 ? 152.987 142.332 149.461 1.00 115.17 ? 297 SER R C   1 
ATOM   2362 O O   . SER A 1 302 ? 153.489 141.351 150.022 1.00 109.66 ? 297 SER R O   1 
ATOM   2363 C CB  . SER A 1 302 ? 154.492 143.457 147.797 1.00 114.97 ? 297 SER R CB  1 
ATOM   2364 O OG  . SER A 1 302 ? 154.201 144.823 148.039 1.00 114.35 ? 297 SER R OG  1 
ATOM   2365 N N   . SER A 1 303 ? 152.215 143.206 150.105 1.00 120.63 ? 298 SER R N   1 
ATOM   2366 C CA  . SER A 1 303 ? 151.879 143.085 151.524 1.00 120.63 ? 298 SER R CA  1 
ATOM   2367 C C   . SER A 1 303 ? 153.123 142.984 152.403 1.00 119.44 ? 298 SER R C   1 
ATOM   2368 O O   . SER A 1 303 ? 154.189 143.487 152.049 1.00 118.60 ? 298 SER R O   1 
ATOM   2369 C CB  . SER A 1 303 ? 150.971 141.874 151.761 1.00 117.67 ? 298 SER R CB  1 
ATOM   2370 O OG  . SER A 1 303 ? 150.664 141.727 153.136 1.00 115.01 ? 298 SER R OG  1 
ATOM   2371 N N   . VAL B 2 2   ? 183.029 175.863 192.498 1.00 83.22  ? 2   VAL D N   1 
ATOM   2372 C CA  . VAL B 2 2   ? 182.572 176.920 193.390 1.00 76.27  ? 2   VAL D CA  1 
ATOM   2373 C C   . VAL B 2 2   ? 183.686 177.927 193.635 1.00 78.89  ? 2   VAL D C   1 
ATOM   2374 O O   . VAL B 2 2   ? 183.779 178.515 194.711 1.00 79.36  ? 2   VAL D O   1 
ATOM   2375 C CB  . VAL B 2 2   ? 182.058 176.342 194.715 1.00 75.96  ? 2   VAL D CB  1 
ATOM   2376 C CG1 . VAL B 2 2   ? 180.799 175.531 194.478 1.00 74.56  ? 2   VAL D CG1 1 
ATOM   2377 C CG2 . VAL B 2 2   ? 183.128 175.484 195.369 1.00 75.21  ? 2   VAL D CG2 1 
ATOM   2378 N N   . GLN B 2 3   ? 184.531 178.129 192.627 1.00 94.76  ? 3   GLN D N   1 
ATOM   2379 C CA  . GLN B 2 3   ? 185.616 179.100 192.708 1.00 93.42  ? 3   GLN D CA  1 
ATOM   2380 C C   . GLN B 2 3   ? 185.763 179.782 191.358 1.00 94.27  ? 3   GLN D C   1 
ATOM   2381 O O   . GLN B 2 3   ? 186.114 179.134 190.366 1.00 98.48  ? 3   GLN D O   1 
ATOM   2382 C CB  . GLN B 2 3   ? 186.928 178.431 193.125 1.00 91.40  ? 3   GLN D CB  1 
ATOM   2383 C CG  . GLN B 2 3   ? 188.151 179.314 192.963 1.00 93.83  ? 3   GLN D CG  1 
ATOM   2384 C CD  . GLN B 2 3   ? 189.442 178.582 193.265 1.00 97.53  ? 3   GLN D CD  1 
ATOM   2385 O OE1 . GLN B 2 3   ? 189.618 177.426 192.880 1.00 98.05  ? 3   GLN D OE1 1 
ATOM   2386 N NE2 . GLN B 2 3   ? 190.354 179.252 193.957 1.00 95.75  ? 3   GLN D NE2 1 
ATOM   2387 N N   . LEU B 2 4   ? 185.494 181.084 191.322 1.00 70.83  ? 4   LEU D N   1 
ATOM   2388 C CA  . LEU B 2 4   ? 185.604 181.886 190.112 1.00 68.39  ? 4   LEU D CA  1 
ATOM   2389 C C   . LEU B 2 4   ? 186.643 182.974 190.334 1.00 76.53  ? 4   LEU D C   1 
ATOM   2390 O O   . LEU B 2 4   ? 186.623 183.655 191.364 1.00 83.08  ? 4   LEU D O   1 
ATOM   2391 C CB  . LEU B 2 4   ? 184.255 182.501 189.738 1.00 70.48  ? 4   LEU D CB  1 
ATOM   2392 C CG  . LEU B 2 4   ? 183.117 181.522 189.450 1.00 71.94  ? 4   LEU D CG  1 
ATOM   2393 C CD1 . LEU B 2 4   ? 181.811 182.044 190.011 1.00 72.11  ? 4   LEU D CD1 1 
ATOM   2394 C CD2 . LEU B 2 4   ? 182.991 181.285 187.960 1.00 75.84  ? 4   LEU D CD2 1 
ATOM   2395 N N   . VAL B 2 5   ? 187.550 183.131 189.372 1.00 90.52  ? 5   VAL D N   1 
ATOM   2396 C CA  . VAL B 2 5   ? 188.631 184.104 189.462 1.00 91.69  ? 5   VAL D CA  1 
ATOM   2397 C C   . VAL B 2 5   ? 188.584 184.987 188.224 1.00 93.35  ? 5   VAL D C   1 
ATOM   2398 O O   . VAL B 2 5   ? 188.136 184.562 187.155 1.00 94.23  ? 5   VAL D O   1 
ATOM   2399 C CB  . VAL B 2 5   ? 190.008 183.408 189.598 1.00 88.59  ? 5   VAL D CB  1 
ATOM   2400 C CG1 . VAL B 2 5   ? 191.123 184.423 189.816 1.00 86.50  ? 5   VAL D CG1 1 
ATOM   2401 C CG2 . VAL B 2 5   ? 189.983 182.391 190.728 1.00 87.42  ? 5   VAL D CG2 1 
ATOM   2402 N N   . GLU B 2 6   ? 189.053 186.225 188.367 1.00 94.22  ? 6   GLU D N   1 
ATOM   2403 C CA  . GLU B 2 6   ? 189.086 187.182 187.274 1.00 91.86  ? 6   GLU D CA  1 
ATOM   2404 C C   . GLU B 2 6   ? 190.504 187.698 187.071 1.00 94.84  ? 6   GLU D C   1 
ATOM   2405 O O   . GLU B 2 6   ? 191.331 187.686 187.986 1.00 97.87  ? 6   GLU D O   1 
ATOM   2406 C CB  . GLU B 2 6   ? 188.150 188.368 187.532 1.00 97.00  ? 6   GLU D CB  1 
ATOM   2407 C CG  . GLU B 2 6   ? 186.674 188.079 187.343 1.00 99.62  ? 6   GLU D CG  1 
ATOM   2408 C CD  . GLU B 2 6   ? 185.950 187.892 188.659 1.00 99.57  ? 6   GLU D CD  1 
ATOM   2409 O OE1 . GLU B 2 6   ? 186.596 187.469 189.640 1.00 99.89  ? 6   GLU D OE1 1 
ATOM   2410 O OE2 . GLU B 2 6   ? 184.743 188.201 188.721 1.00 92.54  ? 6   GLU D OE2 1 
ATOM   2411 N N   . SER B 2 7   ? 190.774 188.155 185.850 1.00 98.41  ? 7   SER D N   1 
ATOM   2412 C CA  . SER B 2 7   ? 192.078 188.716 185.527 1.00 98.04  ? 7   SER D CA  1 
ATOM   2413 C C   . SER B 2 7   ? 191.951 189.619 184.310 1.00 100.65 ? 7   SER D C   1 
ATOM   2414 O O   . SER B 2 7   ? 190.987 189.532 183.544 1.00 103.47 ? 7   SER D O   1 
ATOM   2415 C CB  . SER B 2 7   ? 193.114 187.616 185.272 1.00 97.46  ? 7   SER D CB  1 
ATOM   2416 O OG  . SER B 2 7   ? 194.376 188.172 184.952 1.00 98.44  ? 7   SER D OG  1 
ATOM   2417 N N   . GLY B 2 8   ? 192.943 190.492 184.145 1.00 93.83  ? 8   GLY D N   1 
ATOM   2418 C CA  . GLY B 2 8   ? 193.044 191.354 182.985 1.00 93.55  ? 8   GLY D CA  1 
ATOM   2419 C C   . GLY B 2 8   ? 192.829 192.826 183.256 1.00 91.89  ? 8   GLY D C   1 
ATOM   2420 O O   . GLY B 2 8   ? 193.044 193.639 182.349 1.00 93.77  ? 8   GLY D O   1 
ATOM   2421 N N   . GLY B 2 9   ? 192.419 193.201 184.463 1.00 94.75  ? 9   GLY D N   1 
ATOM   2422 C CA  . GLY B 2 9   ? 192.131 194.584 184.774 1.00 97.45  ? 9   GLY D CA  1 
ATOM   2423 C C   . GLY B 2 9   ? 193.390 195.416 184.924 1.00 96.84  ? 9   GLY D C   1 
ATOM   2424 O O   . GLY B 2 9   ? 194.517 194.942 184.772 1.00 97.66  ? 9   GLY D O   1 
ATOM   2425 N N   . GLY B 2 10  ? 193.181 196.694 185.232 1.00 87.01  ? 10  GLY D N   1 
ATOM   2426 C CA  . GLY B 2 10  ? 194.296 197.599 185.428 1.00 88.19  ? 10  GLY D CA  1 
ATOM   2427 C C   . GLY B 2 10  ? 194.074 199.001 184.900 1.00 90.53  ? 10  GLY D C   1 
ATOM   2428 O O   . GLY B 2 10  ? 192.937 199.478 184.831 1.00 91.94  ? 10  GLY D O   1 
ATOM   2429 N N   . LEU B 2 11  ? 195.161 199.664 184.516 1.00 87.50  ? 11  LEU D N   1 
ATOM   2430 C CA  . LEU B 2 11  ? 195.133 201.049 184.066 1.00 84.89  ? 11  LEU D CA  1 
ATOM   2431 C C   . LEU B 2 11  ? 195.200 201.086 182.545 1.00 85.21  ? 11  LEU D C   1 
ATOM   2432 O O   . LEU B 2 11  ? 196.052 200.428 181.939 1.00 84.70  ? 11  LEU D O   1 
ATOM   2433 C CB  . LEU B 2 11  ? 196.299 201.834 184.671 1.00 83.23  ? 11  LEU D CB  1 
ATOM   2434 C CG  . LEU B 2 11  ? 196.535 203.295 184.277 1.00 86.51  ? 11  LEU D CG  1 
ATOM   2435 C CD1 . LEU B 2 11  ? 195.227 204.063 184.128 1.00 85.72  ? 11  LEU D CD1 1 
ATOM   2436 C CD2 . LEU B 2 11  ? 197.445 203.974 185.288 1.00 88.82  ? 11  LEU D CD2 1 
ATOM   2437 N N   . VAL B 2 12  ? 194.297 201.854 181.934 1.00 93.94  ? 12  VAL D N   1 
ATOM   2438 C CA  . VAL B 2 12  ? 194.187 201.938 180.484 1.00 92.14  ? 12  VAL D CA  1 
ATOM   2439 C C   . VAL B 2 12  ? 194.028 203.395 180.070 1.00 92.29  ? 12  VAL D C   1 
ATOM   2440 O O   . VAL B 2 12  ? 193.690 204.263 180.877 1.00 96.77  ? 12  VAL D O   1 
ATOM   2441 C CB  . VAL B 2 12  ? 193.006 201.104 179.953 1.00 92.09  ? 12  VAL D CB  1 
ATOM   2442 C CG1 . VAL B 2 12  ? 193.367 199.631 179.936 1.00 94.56  ? 12  VAL D CG1 1 
ATOM   2443 C CG2 . VAL B 2 12  ? 191.797 201.332 180.835 1.00 93.72  ? 12  VAL D CG2 1 
ATOM   2444 N N   . GLN B 2 13  ? 194.287 203.653 178.792 1.00 85.91  ? 13  GLN D N   1 
ATOM   2445 C CA  . GLN B 2 13  ? 194.125 204.968 178.199 1.00 83.80  ? 13  GLN D CA  1 
ATOM   2446 C C   . GLN B 2 13  ? 192.943 204.964 177.234 1.00 89.24  ? 13  GLN D C   1 
ATOM   2447 O O   . GLN B 2 13  ? 192.563 203.907 176.720 1.00 91.68  ? 13  GLN D O   1 
ATOM   2448 C CB  . GLN B 2 13  ? 195.396 205.404 177.456 1.00 82.01  ? 13  GLN D CB  1 
ATOM   2449 C CG  . GLN B 2 13  ? 195.545 204.821 176.063 1.00 89.19  ? 13  GLN D CG  1 
ATOM   2450 C CD  . GLN B 2 13  ? 195.840 203.336 176.079 1.00 95.92  ? 13  GLN D CD  1 
ATOM   2451 O OE1 . GLN B 2 13  ? 196.399 202.812 177.042 1.00 97.35  ? 13  GLN D OE1 1 
ATOM   2452 N NE2 . GLN B 2 13  ? 195.463 202.646 175.008 1.00 94.30  ? 13  GLN D NE2 1 
ATOM   2453 N N   . PRO B 2 14  ? 192.322 206.118 176.987 1.00 91.31  ? 14  PRO D N   1 
ATOM   2454 C CA  . PRO B 2 14  ? 191.158 206.147 176.093 1.00 89.14  ? 14  PRO D CA  1 
ATOM   2455 C C   . PRO B 2 14  ? 191.504 205.653 174.697 1.00 90.32  ? 14  PRO D C   1 
ATOM   2456 O O   . PRO B 2 14  ? 192.606 205.877 174.192 1.00 93.67  ? 14  PRO D O   1 
ATOM   2457 C CB  . PRO B 2 14  ? 190.752 207.626 176.083 1.00 85.88  ? 14  PRO D CB  1 
ATOM   2458 C CG  . PRO B 2 14  ? 191.937 208.364 176.614 1.00 87.92  ? 14  PRO D CG  1 
ATOM   2459 C CD  . PRO B 2 14  ? 192.586 207.437 177.582 1.00 88.51  ? 14  PRO D CD  1 
ATOM   2460 N N   . GLY B 2 15  ? 190.545 204.971 174.077 1.00 99.89  ? 15  GLY D N   1 
ATOM   2461 C CA  . GLY B 2 15  ? 190.716 204.447 172.741 1.00 102.12 ? 15  GLY D CA  1 
ATOM   2462 C C   . GLY B 2 15  ? 191.361 203.082 172.655 1.00 103.79 ? 15  GLY D C   1 
ATOM   2463 O O   . GLY B 2 15  ? 191.510 202.557 171.544 1.00 105.19 ? 15  GLY D O   1 
ATOM   2464 N N   . GLY B 2 16  ? 191.750 202.487 173.783 1.00 100.67 ? 16  GLY D N   1 
ATOM   2465 C CA  . GLY B 2 16  ? 192.350 201.172 173.782 1.00 99.09  ? 16  GLY D CA  1 
ATOM   2466 C C   . GLY B 2 16  ? 191.319 200.057 173.781 1.00 99.51  ? 16  GLY D C   1 
ATOM   2467 O O   . GLY B 2 16  ? 190.109 200.277 173.739 1.00 98.99  ? 16  GLY D O   1 
ATOM   2468 N N   . SER B 2 17  ? 191.828 198.829 173.829 1.00 106.94 ? 17  SER D N   1 
ATOM   2469 C CA  . SER B 2 17  ? 191.007 197.630 173.882 1.00 109.59 ? 17  SER D CA  1 
ATOM   2470 C C   . SER B 2 17  ? 191.511 196.740 175.006 1.00 111.74 ? 17  SER D C   1 
ATOM   2471 O O   . SER B 2 17  ? 192.705 196.727 175.315 1.00 110.54 ? 17  SER D O   1 
ATOM   2472 C CB  . SER B 2 17  ? 191.038 196.869 172.550 1.00 111.36 ? 17  SER D CB  1 
ATOM   2473 O OG  . SER B 2 17  ? 192.358 196.798 172.038 1.00 111.24 ? 17  SER D OG  1 
ATOM   2474 N N   . ARG B 2 18  ? 190.597 195.991 175.622 1.00 100.77 ? 18  ARG D N   1 
ATOM   2475 C CA  . ARG B 2 18  ? 190.970 195.176 176.772 1.00 95.30  ? 18  ARG D CA  1 
ATOM   2476 C C   . ARG B 2 18  ? 190.314 193.806 176.694 1.00 93.79  ? 18  ARG D C   1 
ATOM   2477 O O   . ARG B 2 18  ? 189.294 193.617 176.033 1.00 94.33  ? 18  ARG D O   1 
ATOM   2478 C CB  . ARG B 2 18  ? 190.601 195.859 178.092 1.00 94.90  ? 18  ARG D CB  1 
ATOM   2479 C CG  . ARG B 2 18  ? 191.598 195.601 179.201 1.00 94.36  ? 18  ARG D CG  1 
ATOM   2480 C CD  . ARG B 2 18  ? 193.021 195.803 178.719 1.00 93.01  ? 18  ARG D CD  1 
ATOM   2481 N NE  . ARG B 2 18  ? 193.972 195.814 179.823 1.00 97.65  ? 18  ARG D NE  1 
ATOM   2482 C CZ  . ARG B 2 18  ? 195.277 195.625 179.688 1.00 98.98  ? 18  ARG D CZ  1 
ATOM   2483 N NH1 . ARG B 2 18  ? 195.825 195.408 178.503 1.00 99.74  ? 18  ARG D NH1 1 
ATOM   2484 N NH2 . ARG B 2 18  ? 196.052 195.654 180.768 1.00 96.82  ? 18  ARG D NH2 1 
ATOM   2485 N N   . LYS B 2 19  ? 190.926 192.844 177.383 1.00 101.92 ? 19  LYS D N   1 
ATOM   2486 C CA  . LYS B 2 19  ? 190.436 191.468 177.441 1.00 104.52 ? 19  LYS D CA  1 
ATOM   2487 C C   . LYS B 2 19  ? 190.358 191.050 178.906 1.00 105.80 ? 19  LYS D C   1 
ATOM   2488 O O   . LYS B 2 19  ? 191.388 190.829 179.551 1.00 107.14 ? 19  LYS D O   1 
ATOM   2489 C CB  . LYS B 2 19  ? 191.337 190.525 176.647 1.00 104.37 ? 19  LYS D CB  1 
ATOM   2490 C CG  . LYS B 2 19  ? 191.326 190.758 175.144 1.00 105.13 ? 19  LYS D CG  1 
ATOM   2491 N N   . LEU B 2 20  ? 189.140 190.943 179.428 1.00 92.15  ? 20  LEU D N   1 
ATOM   2492 C CA  . LEU B 2 20  ? 188.912 190.486 180.790 1.00 90.34  ? 20  LEU D CA  1 
ATOM   2493 C C   . LEU B 2 20  ? 188.572 189.002 180.765 1.00 95.53  ? 20  LEU D C   1 
ATOM   2494 O O   . LEU B 2 20  ? 187.713 188.571 179.989 1.00 96.16  ? 20  LEU D O   1 
ATOM   2495 C CB  . LEU B 2 20  ? 187.780 191.280 181.439 1.00 92.55  ? 20  LEU D CB  1 
ATOM   2496 C CG  . LEU B 2 20  ? 188.159 192.556 182.188 1.00 94.93  ? 20  LEU D CG  1 
ATOM   2497 C CD1 . LEU B 2 20  ? 187.064 192.941 183.169 1.00 96.85  ? 20  LEU D CD1 1 
ATOM   2498 C CD2 . LEU B 2 20  ? 189.482 192.380 182.903 1.00 92.64  ? 20  LEU D CD2 1 
ATOM   2499 N N   . SER B 2 21  ? 189.244 188.223 181.610 1.00 101.85 ? 21  SER D N   1 
ATOM   2500 C CA  . SER B 2 21  ? 189.100 186.775 181.614 1.00 103.47 ? 21  SER D CA  1 
ATOM   2501 C C   . SER B 2 21  ? 188.567 186.298 182.957 1.00 103.03 ? 21  SER D C   1 
ATOM   2502 O O   . SER B 2 21  ? 188.961 186.808 184.011 1.00 99.30  ? 21  SER D O   1 
ATOM   2503 C CB  . SER B 2 21  ? 190.434 186.087 181.312 1.00 99.55  ? 21  SER D CB  1 
ATOM   2504 O OG  . SER B 2 21  ? 191.494 186.697 182.026 1.00 98.88  ? 21  SER D OG  1 
ATOM   2505 N N   . CYS B 2 22  ? 187.667 185.317 182.907 1.00 95.03  ? 22  CYS D N   1 
ATOM   2506 C CA  . CYS B 2 22  ? 187.130 184.657 184.088 1.00 88.69  ? 22  CYS D CA  1 
ATOM   2507 C C   . CYS B 2 22  ? 187.402 183.166 183.987 1.00 95.69  ? 22  CYS D C   1 
ATOM   2508 O O   . CYS B 2 22  ? 187.101 182.544 182.963 1.00 97.56  ? 22  CYS D O   1 
ATOM   2509 C CB  . CYS B 2 22  ? 185.628 184.901 184.228 1.00 89.24  ? 22  CYS D CB  1 
ATOM   2510 S SG  . CYS B 2 22  ? 184.807 183.750 185.347 1.00 89.76  ? 22  CYS D SG  1 
ATOM   2511 N N   . SER B 2 23  ? 187.963 182.599 185.051 1.00 102.93 ? 23  SER D N   1 
ATOM   2512 C CA  . SER B 2 23  ? 188.271 181.178 185.132 1.00 99.41  ? 23  SER D CA  1 
ATOM   2513 C C   . SER B 2 23  ? 187.411 180.538 186.211 1.00 99.70  ? 23  SER D C   1 
ATOM   2514 O O   . SER B 2 23  ? 187.328 181.053 187.333 1.00 103.53 ? 23  SER D O   1 
ATOM   2515 C CB  . SER B 2 23  ? 189.754 180.953 185.431 1.00 94.86  ? 23  SER D CB  1 
ATOM   2516 O OG  . SER B 2 23  ? 190.565 181.414 184.364 1.00 97.24  ? 23  SER D OG  1 
ATOM   2517 N N   . ALA B 2 24  ? 186.776 179.421 185.870 1.00 87.10  ? 24  ALA D N   1 
ATOM   2518 C CA  . ALA B 2 24  ? 185.855 178.726 186.756 1.00 85.78  ? 24  ALA D CA  1 
ATOM   2519 C C   . ALA B 2 24  ? 186.435 177.379 187.161 1.00 89.07  ? 24  ALA D C   1 
ATOM   2520 O O   . ALA B 2 24  ? 187.104 176.717 186.362 1.00 93.42  ? 24  ALA D O   1 
ATOM   2521 C CB  . ALA B 2 24  ? 184.497 178.522 186.082 1.00 85.67  ? 24  ALA D CB  1 
ATOM   2522 N N   . SER B 2 25  ? 186.179 176.977 188.404 1.00 87.38  ? 25  SER D N   1 
ATOM   2523 C CA  . SER B 2 25  ? 186.660 175.693 188.893 1.00 88.84  ? 25  SER D CA  1 
ATOM   2524 C C   . SER B 2 25  ? 185.745 175.198 190.000 1.00 84.95  ? 25  SER D C   1 
ATOM   2525 O O   . SER B 2 25  ? 185.454 175.939 190.944 1.00 88.73  ? 25  SER D O   1 
ATOM   2526 C CB  . SER B 2 25  ? 188.100 175.804 189.405 1.00 87.23  ? 25  SER D CB  1 
ATOM   2527 O OG  . SER B 2 25  ? 188.772 174.561 189.311 1.00 88.25  ? 25  SER D OG  1 
ATOM   2528 N N   . GLY B 2 26  ? 185.294 173.952 189.880 1.00 71.10  ? 26  GLY D N   1 
ATOM   2529 C CA  . GLY B 2 26  ? 184.555 173.297 190.935 1.00 71.47  ? 26  GLY D CA  1 
ATOM   2530 C C   . GLY B 2 26  ? 183.088 173.032 190.675 1.00 72.39  ? 26  GLY D C   1 
ATOM   2531 O O   . GLY B 2 26  ? 182.382 172.634 191.608 1.00 78.09  ? 26  GLY D O   1 
ATOM   2532 N N   . PHE B 2 27  ? 182.600 173.230 189.454 1.00 69.22  ? 27  PHE D N   1 
ATOM   2533 C CA  . PHE B 2 27  ? 181.188 173.006 189.166 1.00 75.84  ? 27  PHE D CA  1 
ATOM   2534 C C   . PHE B 2 27  ? 181.031 172.696 187.680 1.00 76.65  ? 27  PHE D C   1 
ATOM   2535 O O   . PHE B 2 27  ? 182.015 172.528 186.954 1.00 74.45  ? 27  PHE D O   1 
ATOM   2536 C CB  . PHE B 2 27  ? 180.343 174.209 189.608 1.00 76.64  ? 27  PHE D CB  1 
ATOM   2537 C CG  . PHE B 2 27  ? 180.633 175.474 188.849 1.00 74.29  ? 27  PHE D CG  1 
ATOM   2538 C CD1 . PHE B 2 27  ? 181.774 176.210 189.109 1.00 74.72  ? 27  PHE D CD1 1 
ATOM   2539 C CD2 . PHE B 2 27  ? 179.756 175.930 187.882 1.00 74.73  ? 27  PHE D CD2 1 
ATOM   2540 C CE1 . PHE B 2 27  ? 182.038 177.371 188.415 1.00 76.14  ? 27  PHE D CE1 1 
ATOM   2541 C CE2 . PHE B 2 27  ? 180.017 177.091 187.186 1.00 74.98  ? 27  PHE D CE2 1 
ATOM   2542 C CZ  . PHE B 2 27  ? 181.159 177.811 187.453 1.00 75.10  ? 27  PHE D CZ  1 
ATOM   2543 N N   . ALA B 2 28  ? 179.778 172.614 187.231 1.00 80.58  ? 28  ALA D N   1 
ATOM   2544 C CA  . ALA B 2 28  ? 179.443 172.252 185.854 1.00 77.95  ? 28  ALA D CA  1 
ATOM   2545 C C   . ALA B 2 28  ? 179.202 173.533 185.062 1.00 77.29  ? 28  ALA D C   1 
ATOM   2546 O O   . ALA B 2 28  ? 178.108 174.095 185.067 1.00 77.31  ? 28  ALA D O   1 
ATOM   2547 C CB  . ALA B 2 28  ? 178.228 171.332 185.819 1.00 77.42  ? 28  ALA D CB  1 
ATOM   2548 N N   . PHE B 2 29  ? 180.243 173.988 184.362 1.00 74.60  ? 29  PHE D N   1 
ATOM   2549 C CA  . PHE B 2 29  ? 180.155 175.232 183.604 1.00 74.87  ? 29  PHE D CA  1 
ATOM   2550 C C   . PHE B 2 29  ? 179.114 175.133 182.495 1.00 71.85  ? 29  PHE D C   1 
ATOM   2551 O O   . PHE B 2 29  ? 178.332 176.067 182.283 1.00 80.52  ? 29  PHE D O   1 
ATOM   2552 C CB  . PHE B 2 29  ? 181.531 175.571 183.028 1.00 79.81  ? 29  PHE D CB  1 
ATOM   2553 C CG  . PHE B 2 29  ? 181.660 176.975 182.493 1.00 80.74  ? 29  PHE D CG  1 
ATOM   2554 C CD1 . PHE B 2 29  ? 180.625 177.885 182.590 1.00 81.93  ? 29  PHE D CD1 1 
ATOM   2555 C CD2 . PHE B 2 29  ? 182.833 177.376 181.881 1.00 77.25  ? 29  PHE D CD2 1 
ATOM   2556 C CE1 . PHE B 2 29  ? 180.758 179.162 182.089 1.00 80.70  ? 29  PHE D CE1 1 
ATOM   2557 C CE2 . PHE B 2 29  ? 182.971 178.651 181.381 1.00 78.07  ? 29  PHE D CE2 1 
ATOM   2558 C CZ  . PHE B 2 29  ? 181.933 179.546 181.487 1.00 80.18  ? 29  PHE D CZ  1 
ATOM   2559 N N   . SER B 2 30  ? 179.074 174.002 181.791 1.00 69.10  ? 30  SER D N   1 
ATOM   2560 C CA  . SER B 2 30  ? 178.256 173.899 180.587 1.00 77.77  ? 30  SER D CA  1 
ATOM   2561 C C   . SER B 2 30  ? 176.767 174.059 180.863 1.00 79.46  ? 30  SER D C   1 
ATOM   2562 O O   . SER B 2 30  ? 176.004 174.324 179.928 1.00 83.30  ? 30  SER D O   1 
ATOM   2563 C CB  . SER B 2 30  ? 178.514 172.561 179.894 1.00 81.99  ? 30  SER D CB  1 
ATOM   2564 O OG  . SER B 2 30  ? 179.891 172.230 179.924 1.00 80.37  ? 30  SER D OG  1 
ATOM   2565 N N   . SER B 2 31  ? 176.331 173.909 182.111 1.00 75.47  ? 31  SER D N   1 
ATOM   2566 C CA  . SER B 2 31  ? 174.922 174.035 182.453 1.00 77.45  ? 31  SER D CA  1 
ATOM   2567 C C   . SER B 2 31  ? 174.580 175.360 183.125 1.00 79.95  ? 31  SER D C   1 
ATOM   2568 O O   . SER B 2 31  ? 173.412 175.583 183.456 1.00 77.87  ? 31  SER D O   1 
ATOM   2569 C CB  . SER B 2 31  ? 174.496 172.877 183.359 1.00 74.86  ? 31  SER D CB  1 
ATOM   2570 O OG  . SER B 2 31  ? 175.109 171.666 182.954 1.00 74.10  ? 31  SER D OG  1 
ATOM   2571 N N   . PHE B 2 32  ? 175.556 176.240 183.330 1.00 81.88  ? 32  PHE D N   1 
ATOM   2572 C CA  . PHE B 2 32  ? 175.349 177.500 184.032 1.00 73.73  ? 32  PHE D CA  1 
ATOM   2573 C C   . PHE B 2 32  ? 175.551 178.671 183.079 1.00 73.33  ? 32  PHE D C   1 
ATOM   2574 O O   . PHE B 2 32  ? 176.597 178.776 182.431 1.00 78.69  ? 32  PHE D O   1 
ATOM   2575 C CB  . PHE B 2 32  ? 176.307 177.627 185.219 1.00 69.39  ? 32  PHE D CB  1 
ATOM   2576 C CG  . PHE B 2 32  ? 175.828 176.939 186.466 1.00 70.58  ? 32  PHE D CG  1 
ATOM   2577 C CD1 . PHE B 2 32  ? 174.762 177.440 187.186 1.00 74.66  ? 32  PHE D CD1 1 
ATOM   2578 C CD2 . PHE B 2 32  ? 176.448 175.789 186.916 1.00 74.62  ? 32  PHE D CD2 1 
ATOM   2579 C CE1 . PHE B 2 32  ? 174.326 176.808 188.332 1.00 76.15  ? 32  PHE D CE1 1 
ATOM   2580 C CE2 . PHE B 2 32  ? 176.013 175.151 188.056 1.00 77.02  ? 32  PHE D CE2 1 
ATOM   2581 C CZ  . PHE B 2 32  ? 174.951 175.661 188.766 1.00 75.93  ? 32  PHE D CZ  1 
ATOM   2582 N N   . GLY B 2 33  ? 174.548 179.546 182.998 1.00 69.87  ? 33  GLY D N   1 
ATOM   2583 C CA  . GLY B 2 33  ? 174.713 180.798 182.296 1.00 68.76  ? 33  GLY D CA  1 
ATOM   2584 C C   . GLY B 2 33  ? 175.460 181.822 183.128 1.00 70.43  ? 33  GLY D C   1 
ATOM   2585 O O   . GLY B 2 33  ? 175.562 181.714 184.352 1.00 83.11  ? 33  GLY D O   1 
ATOM   2586 N N   . MET B 2 34  ? 175.985 182.844 182.454 1.00 61.07  ? 34  MET D N   1 
ATOM   2587 C CA  . MET B 2 34  ? 176.859 183.805 183.108 1.00 66.84  ? 34  MET D CA  1 
ATOM   2588 C C   . MET B 2 34  ? 176.394 185.237 182.878 1.00 70.49  ? 34  MET D C   1 
ATOM   2589 O O   . MET B 2 34  ? 175.757 185.557 181.870 1.00 77.19  ? 34  MET D O   1 
ATOM   2590 C CB  . MET B 2 34  ? 178.306 183.642 182.639 1.00 63.87  ? 34  MET D CB  1 
ATOM   2591 C CG  . MET B 2 34  ? 178.965 182.384 183.168 1.00 65.69  ? 34  MET D CG  1 
ATOM   2592 S SD  . MET B 2 34  ? 179.629 182.648 184.823 1.00 89.18  ? 34  MET D SD  1 
ATOM   2593 C CE  . MET B 2 34  ? 180.516 181.119 185.096 1.00 76.28  ? 34  MET D CE  1 
ATOM   2594 N N   . HIS B 2 35  ? 176.718 186.088 183.849 1.00 54.52  ? 35  HIS D N   1 
ATOM   2595 C CA  . HIS B 2 35  ? 176.425 187.509 183.820 1.00 44.18  ? 35  HIS D CA  1 
ATOM   2596 C C   . HIS B 2 35  ? 177.688 188.282 184.160 1.00 55.74  ? 35  HIS D C   1 
ATOM   2597 O O   . HIS B 2 35  ? 178.517 187.826 184.951 1.00 71.98  ? 35  HIS D O   1 
ATOM   2598 C CB  . HIS B 2 35  ? 175.343 187.895 184.834 1.00 48.15  ? 35  HIS D CB  1 
ATOM   2599 C CG  . HIS B 2 35  ? 174.007 187.278 184.575 1.00 53.25  ? 35  HIS D CG  1 
ATOM   2600 N ND1 . HIS B 2 35  ? 173.634 186.065 185.110 1.00 60.68  ? 35  HIS D ND1 1 
ATOM   2601 C CD2 . HIS B 2 35  ? 172.940 187.724 183.873 1.00 59.91  ? 35  HIS D CD2 1 
ATOM   2602 C CE1 . HIS B 2 35  ? 172.402 185.780 184.731 1.00 61.40  ? 35  HIS D CE1 1 
ATOM   2603 N NE2 . HIS B 2 35  ? 171.957 186.771 183.982 1.00 63.58  ? 35  HIS D NE2 1 
ATOM   2604 N N   . TRP B 2 36  ? 177.815 189.468 183.576 1.00 65.35  ? 36  TRP D N   1 
ATOM   2605 C CA  . TRP B 2 36  ? 178.819 190.445 183.971 1.00 66.48  ? 36  TRP D CA  1 
ATOM   2606 C C   . TRP B 2 36  ? 178.102 191.679 184.494 1.00 73.01  ? 36  TRP D C   1 
ATOM   2607 O O   . TRP B 2 36  ? 177.249 192.243 183.794 1.00 82.89  ? 36  TRP D O   1 
ATOM   2608 C CB  . TRP B 2 36  ? 179.730 190.824 182.803 1.00 68.57  ? 36  TRP D CB  1 
ATOM   2609 C CG  . TRP B 2 36  ? 180.913 189.933 182.618 1.00 66.29  ? 36  TRP D CG  1 
ATOM   2610 C CD1 . TRP B 2 36  ? 180.998 188.853 181.802 1.00 68.76  ? 36  TRP D CD1 1 
ATOM   2611 C CD2 . TRP B 2 36  ? 182.193 190.063 183.245 1.00 70.14  ? 36  TRP D CD2 1 
ATOM   2612 N NE1 . TRP B 2 36  ? 182.246 188.294 181.881 1.00 65.75  ? 36  TRP D NE1 1 
ATOM   2613 C CE2 . TRP B 2 36  ? 183.000 189.018 182.764 1.00 63.34  ? 36  TRP D CE2 1 
ATOM   2614 C CE3 . TRP B 2 36  ? 182.733 190.959 184.171 1.00 79.57  ? 36  TRP D CE3 1 
ATOM   2615 C CZ2 . TRP B 2 36  ? 184.315 188.841 183.175 1.00 67.47  ? 36  TRP D CZ2 1 
ATOM   2616 C CZ3 . TRP B 2 36  ? 184.041 190.780 184.577 1.00 79.31  ? 36  TRP D CZ3 1 
ATOM   2617 C CH2 . TRP B 2 36  ? 184.816 189.731 184.079 1.00 73.03  ? 36  TRP D CH2 1 
ATOM   2618 N N   . VAL B 2 37  ? 178.462 192.093 185.713 1.00 71.34  ? 37  VAL D N   1 
ATOM   2619 C CA  . VAL B 2 37  ? 177.815 193.190 186.430 1.00 74.13  ? 37  VAL D CA  1 
ATOM   2620 C C   . VAL B 2 37  ? 178.890 194.155 186.914 1.00 81.57  ? 37  VAL D C   1 
ATOM   2621 O O   . VAL B 2 37  ? 179.900 193.729 187.481 1.00 85.63  ? 37  VAL D O   1 
ATOM   2622 C CB  . VAL B 2 37  ? 176.979 192.673 187.618 1.00 70.97  ? 37  VAL D CB  1 
ATOM   2623 C CG1 . VAL B 2 37  ? 176.510 193.821 188.490 1.00 75.26  ? 37  VAL D CG1 1 
ATOM   2624 C CG2 . VAL B 2 37  ? 175.798 191.861 187.125 1.00 73.12  ? 37  VAL D CG2 1 
ATOM   2625 N N   . ARG B 2 38  ? 178.669 195.451 186.717 1.00 86.49  ? 38  ARG D N   1 
ATOM   2626 C CA  . ARG B 2 38  ? 179.677 196.466 186.998 1.00 82.03  ? 38  ARG D CA  1 
ATOM   2627 C C   . ARG B 2 38  ? 179.298 197.264 188.238 1.00 83.33  ? 38  ARG D C   1 
ATOM   2628 O O   . ARG B 2 38  ? 178.118 197.544 188.468 1.00 85.97  ? 38  ARG D O   1 
ATOM   2629 C CB  . ARG B 2 38  ? 179.846 197.400 185.796 1.00 85.24  ? 38  ARG D CB  1 
ATOM   2630 C CG  . ARG B 2 38  ? 180.722 198.612 186.033 1.00 88.72  ? 38  ARG D CG  1 
ATOM   2631 C CD  . ARG B 2 38  ? 181.055 199.308 184.721 1.00 88.34  ? 38  ARG D CD  1 
ATOM   2632 N NE  . ARG B 2 38  ? 179.864 199.825 184.059 1.00 87.22  ? 38  ARG D NE  1 
ATOM   2633 C CZ  . ARG B 2 38  ? 179.785 200.092 182.763 1.00 86.28  ? 38  ARG D CZ  1 
ATOM   2634 N NH1 . ARG B 2 38  ? 180.809 199.893 181.952 1.00 86.32  ? 38  ARG D NH1 1 
ATOM   2635 N NH2 . ARG B 2 38  ? 178.646 200.568 182.268 1.00 87.82  ? 38  ARG D NH2 1 
ATOM   2636 N N   . GLN B 2 39  ? 180.302 197.627 189.039 1.00 98.29  ? 39  GLN D N   1 
ATOM   2637 C CA  . GLN B 2 39  ? 180.103 198.420 190.245 1.00 100.01 ? 39  GLN D CA  1 
ATOM   2638 C C   . GLN B 2 39  ? 181.032 199.623 190.205 1.00 101.94 ? 39  GLN D C   1 
ATOM   2639 O O   . GLN B 2 39  ? 182.252 199.464 190.087 1.00 105.28 ? 39  GLN D O   1 
ATOM   2640 C CB  . GLN B 2 39  ? 180.363 197.585 191.501 1.00 101.32 ? 39  GLN D CB  1 
ATOM   2641 C CG  . GLN B 2 39  ? 180.718 198.404 192.729 1.00 100.69 ? 39  GLN D CG  1 
ATOM   2642 C CD  . GLN B 2 39  ? 179.507 199.023 193.387 1.00 101.15 ? 39  GLN D CD  1 
ATOM   2643 O OE1 . GLN B 2 39  ? 178.372 198.784 192.977 1.00 101.16 ? 39  GLN D OE1 1 
ATOM   2644 N NE2 . GLN B 2 39  ? 179.741 199.832 194.413 1.00 100.00 ? 39  GLN D NE2 1 
ATOM   2645 N N   . ALA B 2 40  ? 180.457 200.817 190.309 1.00 100.36 ? 40  ALA D N   1 
ATOM   2646 C CA  . ALA B 2 40  ? 181.236 202.041 190.312 1.00 100.57 ? 40  ALA D CA  1 
ATOM   2647 C C   . ALA B 2 40  ? 182.014 202.166 191.621 1.00 103.22 ? 40  ALA D C   1 
ATOM   2648 O O   . ALA B 2 40  ? 181.640 201.568 192.633 1.00 105.75 ? 40  ALA D O   1 
ATOM   2649 C CB  . ALA B 2 40  ? 180.316 203.244 190.114 1.00 101.52 ? 40  ALA D CB  1 
ATOM   2650 N N   . PRO B 2 41  ? 183.111 202.932 191.627 1.00 103.54 ? 41  PRO D N   1 
ATOM   2651 C CA  . PRO B 2 41  ? 183.923 203.027 192.854 1.00 104.51 ? 41  PRO D CA  1 
ATOM   2652 C C   . PRO B 2 41  ? 183.186 203.627 194.039 1.00 104.94 ? 41  PRO D C   1 
ATOM   2653 O O   . PRO B 2 41  ? 183.584 203.375 195.183 1.00 104.49 ? 41  PRO D O   1 
ATOM   2654 C CB  . PRO B 2 41  ? 185.119 203.900 192.443 1.00 102.13 ? 41  PRO D CB  1 
ATOM   2655 C CG  . PRO B 2 41  ? 184.980 204.181 191.004 1.00 101.53 ? 41  PRO D CG  1 
ATOM   2656 C CD  . PRO B 2 41  ? 183.649 203.739 190.518 1.00 100.76 ? 41  PRO D CD  1 
ATOM   2657 N N   . GLU B 2 42  ? 182.132 204.415 193.813 1.00 114.51 ? 42  GLU D N   1 
ATOM   2658 C CA  . GLU B 2 42  ? 181.373 204.974 194.925 1.00 114.54 ? 42  GLU D CA  1 
ATOM   2659 C C   . GLU B 2 42  ? 179.867 204.969 194.682 1.00 114.64 ? 42  GLU D C   1 
ATOM   2660 O O   . GLU B 2 42  ? 179.139 205.653 195.413 1.00 116.61 ? 42  GLU D O   1 
ATOM   2661 C CB  . GLU B 2 42  ? 181.840 206.404 195.228 1.00 114.20 ? 42  GLU D CB  1 
ATOM   2662 C CG  . GLU B 2 42  ? 181.999 207.281 193.998 1.00 116.14 ? 42  GLU D CG  1 
ATOM   2663 C CD  . GLU B 2 42  ? 180.746 208.074 193.683 1.00 116.57 ? 42  GLU D CD  1 
ATOM   2664 O OE1 . GLU B 2 42  ? 179.927 208.283 194.602 1.00 115.95 ? 42  GLU D OE1 1 
ATOM   2665 O OE2 . GLU B 2 42  ? 180.579 208.486 192.516 1.00 114.89 ? 42  GLU D OE2 1 
ATOM   2666 N N   . LYS B 2 43  ? 179.377 204.228 193.697 1.00 103.79 ? 43  LYS D N   1 
ATOM   2667 C CA  . LYS B 2 43  ? 177.963 204.206 193.347 1.00 104.64 ? 43  LYS D CA  1 
ATOM   2668 C C   . LYS B 2 43  ? 177.453 202.765 193.409 1.00 105.42 ? 43  LYS D C   1 
ATOM   2669 O O   . LYS B 2 43  ? 178.166 201.848 193.822 1.00 102.91 ? 43  LYS D O   1 
ATOM   2670 C CB  . LYS B 2 43  ? 177.749 204.839 191.967 1.00 106.42 ? 43  LYS D CB  1 
ATOM   2671 N N   . GLY B 2 44  ? 176.201 202.571 192.997 1.00 106.86 ? 44  GLY D N   1 
ATOM   2672 C CA  . GLY B 2 44  ? 175.556 201.280 193.088 1.00 105.45 ? 44  GLY D CA  1 
ATOM   2673 C C   . GLY B 2 44  ? 175.868 200.363 191.920 1.00 107.68 ? 44  GLY D C   1 
ATOM   2674 O O   . GLY B 2 44  ? 176.652 200.673 191.023 1.00 109.16 ? 44  GLY D O   1 
ATOM   2675 N N   . LEU B 2 45  ? 175.226 199.199 191.945 1.00 94.36  ? 45  LEU D N   1 
ATOM   2676 C CA  . LEU B 2 45  ? 175.439 198.160 190.951 1.00 90.93  ? 45  LEU D CA  1 
ATOM   2677 C C   . LEU B 2 45  ? 174.702 198.486 189.655 1.00 96.00  ? 45  LEU D C   1 
ATOM   2678 O O   . LEU B 2 45  ? 173.683 199.181 189.643 1.00 97.99  ? 45  LEU D O   1 
ATOM   2679 C CB  . LEU B 2 45  ? 174.966 196.808 191.484 1.00 90.34  ? 45  LEU D CB  1 
ATOM   2680 C CG  . LEU B 2 45  ? 175.809 196.130 192.563 1.00 91.82  ? 45  LEU D CG  1 
ATOM   2681 C CD1 . LEU B 2 45  ? 175.188 194.804 192.966 1.00 91.92  ? 45  LEU D CD1 1 
ATOM   2682 C CD2 . LEU B 2 45  ? 177.230 195.926 192.080 1.00 91.47  ? 45  LEU D CD2 1 
ATOM   2683 N N   . GLU B 2 46  ? 175.235 197.969 188.550 1.00 94.90  ? 46  GLU D N   1 
ATOM   2684 C CA  . GLU B 2 46  ? 174.571 198.077 187.259 1.00 91.35  ? 46  GLU D CA  1 
ATOM   2685 C C   . GLU B 2 46  ? 175.044 196.936 186.370 1.00 89.86  ? 46  GLU D C   1 
ATOM   2686 O O   . GLU B 2 46  ? 176.212 196.540 186.414 1.00 94.43  ? 46  GLU D O   1 
ATOM   2687 C CB  . GLU B 2 46  ? 174.832 199.435 186.596 1.00 94.45  ? 46  GLU D CB  1 
ATOM   2688 C CG  . GLU B 2 46  ? 176.291 199.740 186.311 1.00 96.33  ? 46  GLU D CG  1 
ATOM   2689 C CD  . GLU B 2 46  ? 176.470 200.560 185.048 1.00 96.62  ? 46  GLU D CD  1 
ATOM   2690 O OE1 . GLU B 2 46  ? 175.922 201.680 184.981 1.00 93.51  ? 46  GLU D OE1 1 
ATOM   2691 O OE2 . GLU B 2 46  ? 177.153 200.083 184.120 1.00 97.23  ? 46  GLU D OE2 1 
ATOM   2692 N N   . TRP B 2 47  ? 174.122 196.415 185.569 1.00 69.46  ? 47  TRP D N   1 
ATOM   2693 C CA  . TRP B 2 47  ? 174.356 195.226 184.763 1.00 66.82  ? 47  TRP D CA  1 
ATOM   2694 C C   . TRP B 2 47  ? 175.129 195.573 183.496 1.00 69.69  ? 47  TRP D C   1 
ATOM   2695 O O   . TRP B 2 47  ? 175.061 196.697 182.993 1.00 78.80  ? 47  TRP D O   1 
ATOM   2696 C CB  . TRP B 2 47  ? 173.023 194.568 184.407 1.00 65.71  ? 47  TRP D CB  1 
ATOM   2697 C CG  . TRP B 2 47  ? 173.121 193.435 183.446 1.00 59.99  ? 47  TRP D CG  1 
ATOM   2698 C CD1 . TRP B 2 47  ? 173.783 192.263 183.632 1.00 68.41  ? 47  TRP D CD1 1 
ATOM   2699 C CD2 . TRP B 2 47  ? 172.531 193.361 182.145 1.00 68.84  ? 47  TRP D CD2 1 
ATOM   2700 N NE1 . TRP B 2 47  ? 173.645 191.460 182.528 1.00 66.37  ? 47  TRP D NE1 1 
ATOM   2701 C CE2 . TRP B 2 47  ? 172.882 192.114 181.599 1.00 67.57  ? 47  TRP D CE2 1 
ATOM   2702 C CE3 . TRP B 2 47  ? 171.745 194.233 181.387 1.00 79.80  ? 47  TRP D CE3 1 
ATOM   2703 C CZ2 . TRP B 2 47  ? 172.471 191.713 180.331 1.00 75.53  ? 47  TRP D CZ2 1 
ATOM   2704 C CZ3 . TRP B 2 47  ? 171.337 193.834 180.128 1.00 81.72  ? 47  TRP D CZ3 1 
ATOM   2705 C CH2 . TRP B 2 47  ? 171.701 192.585 179.612 1.00 83.75  ? 47  TRP D CH2 1 
ATOM   2706 N N   . VAL B 2 48  ? 175.872 194.592 182.981 1.00 60.09  ? 48  VAL D N   1 
ATOM   2707 C CA  . VAL B 2 48  ? 176.637 194.789 181.753 1.00 59.85  ? 48  VAL D CA  1 
ATOM   2708 C C   . VAL B 2 48  ? 176.212 193.801 180.675 1.00 64.80  ? 48  VAL D C   1 
ATOM   2709 O O   . VAL B 2 48  ? 175.824 194.208 179.574 1.00 69.39  ? 48  VAL D O   1 
ATOM   2710 C CB  . VAL B 2 48  ? 178.148 194.686 182.009 1.00 62.94  ? 48  VAL D CB  1 
ATOM   2711 C CG1 . VAL B 2 48  ? 178.903 194.794 180.701 1.00 65.37  ? 48  VAL D CG1 1 
ATOM   2712 C CG2 . VAL B 2 48  ? 178.588 195.773 182.958 1.00 69.35  ? 48  VAL D CG2 1 
ATOM   2713 N N   . ALA B 2 49  ? 176.275 192.503 180.965 1.00 64.89  ? 49  ALA D N   1 
ATOM   2714 C CA  . ALA B 2 49  ? 176.028 191.546 179.890 1.00 60.91  ? 49  ALA D CA  1 
ATOM   2715 C C   . ALA B 2 49  ? 175.514 190.224 180.442 1.00 63.45  ? 49  ALA D C   1 
ATOM   2716 O O   . ALA B 2 49  ? 175.737 189.887 181.607 1.00 76.41  ? 49  ALA D O   1 
ATOM   2717 C CB  . ALA B 2 49  ? 177.291 191.312 179.056 1.00 66.17  ? 49  ALA D CB  1 
ATOM   2718 N N   . TYR B 2 50  ? 174.838 189.468 179.571 1.00 55.23  ? 50  TYR D N   1 
ATOM   2719 C CA  . TYR B 2 50  ? 174.324 188.143 179.903 1.00 56.03  ? 50  TYR D CA  1 
ATOM   2720 C C   . TYR B 2 50  ? 174.541 187.175 178.749 1.00 62.48  ? 50  TYR D C   1 
ATOM   2721 O O   . TYR B 2 50  ? 174.201 187.486 177.601 1.00 69.17  ? 50  TYR D O   1 
ATOM   2722 C CB  . TYR B 2 50  ? 172.834 188.196 180.250 1.00 53.76  ? 50  TYR D CB  1 
ATOM   2723 C CG  . TYR B 2 50  ? 172.161 186.841 180.257 1.00 49.42  ? 50  TYR D CG  1 
ATOM   2724 C CD1 . TYR B 2 50  ? 172.589 185.834 181.106 1.00 55.59  ? 50  TYR D CD1 1 
ATOM   2725 C CD2 . TYR B 2 50  ? 171.095 186.573 179.416 1.00 53.11  ? 50  TYR D CD2 1 
ATOM   2726 C CE1 . TYR B 2 50  ? 171.974 184.599 181.116 1.00 57.27  ? 50  TYR D CE1 1 
ATOM   2727 C CE2 . TYR B 2 50  ? 170.476 185.342 179.419 1.00 50.11  ? 50  TYR D CE2 1 
ATOM   2728 C CZ  . TYR B 2 50  ? 170.918 184.360 180.270 1.00 49.74  ? 50  TYR D CZ  1 
ATOM   2729 O OH  . TYR B 2 50  ? 170.302 183.133 180.273 1.00 57.74  ? 50  TYR D OH  1 
ATOM   2730 N N   . ILE B 2 51  ? 175.085 185.997 179.069 1.00 65.35  ? 51  ILE D N   1 
ATOM   2731 C CA  . ILE B 2 51  ? 175.235 184.883 178.139 1.00 60.17  ? 51  ILE D CA  1 
ATOM   2732 C C   . ILE B 2 51  ? 174.517 183.673 178.716 1.00 68.54  ? 51  ILE D C   1 
ATOM   2733 O O   . ILE B 2 51  ? 174.642 183.376 179.910 1.00 78.78  ? 51  ILE D O   1 
ATOM   2734 C CB  . ILE B 2 51  ? 176.713 184.541 177.877 1.00 50.13  ? 51  ILE D CB  1 
ATOM   2735 C CG1 . ILE B 2 51  ? 177.507 185.803 177.578 1.00 61.34  ? 51  ILE D CG1 1 
ATOM   2736 C CG2 . ILE B 2 51  ? 176.832 183.558 176.731 1.00 54.62  ? 51  ILE D CG2 1 
ATOM   2737 C CD1 . ILE B 2 51  ? 177.036 186.531 176.363 1.00 68.35  ? 51  ILE D CD1 1 
ATOM   2738 N N   . SER B 2 52  ? 173.776 182.971 177.867 1.00 67.89  ? 52  SER D N   1 
ATOM   2739 C CA  . SER B 2 52  ? 173.018 181.802 178.279 1.00 69.81  ? 52  SER D CA  1 
ATOM   2740 C C   . SER B 2 52  ? 173.785 180.526 177.957 1.00 72.81  ? 52  SER D C   1 
ATOM   2741 O O   . SER B 2 52  ? 174.809 180.537 177.271 1.00 76.08  ? 52  SER D O   1 
ATOM   2742 C CB  . SER B 2 52  ? 171.645 181.779 177.604 1.00 71.72  ? 52  SER D CB  1 
ATOM   2743 O OG  . SER B 2 52  ? 170.982 180.554 177.857 1.00 73.36  ? 52  SER D OG  1 
ATOM   2744 N N   . SER B 2 53  ? 173.271 179.414 178.474 1.00 86.04  ? 53  SER D N   1 
ATOM   2745 C CA  . SER B 2 53  ? 173.902 178.121 178.248 1.00 86.09  ? 53  SER D CA  1 
ATOM   2746 C C   . SER B 2 53  ? 173.808 177.729 176.780 1.00 89.85  ? 53  SER D C   1 
ATOM   2747 O O   . SER B 2 53  ? 172.761 177.878 176.145 1.00 90.76  ? 53  SER D O   1 
ATOM   2748 C CB  . SER B 2 53  ? 173.246 177.055 179.123 1.00 84.30  ? 53  SER D CB  1 
ATOM   2749 O OG  . SER B 2 53  ? 171.843 177.033 178.930 1.00 86.36  ? 53  SER D OG  1 
ATOM   2750 N N   . GLY B 2 54  ? 174.915 177.225 176.241 1.00 82.30  ? 54  GLY D N   1 
ATOM   2751 C CA  . GLY B 2 54  ? 174.972 176.836 174.851 1.00 82.44  ? 54  GLY D CA  1 
ATOM   2752 C C   . GLY B 2 54  ? 175.204 177.966 173.874 1.00 81.04  ? 54  GLY D C   1 
ATOM   2753 O O   . GLY B 2 54  ? 175.185 177.721 172.660 1.00 82.14  ? 54  GLY D O   1 
ATOM   2754 N N   . SER B 2 55  ? 175.419 179.190 174.359 1.00 80.04  ? 55  SER D N   1 
ATOM   2755 C CA  . SER B 2 55  ? 175.694 180.351 173.511 1.00 80.60  ? 55  SER D CA  1 
ATOM   2756 C C   . SER B 2 55  ? 174.566 180.585 172.507 1.00 78.10  ? 55  SER D C   1 
ATOM   2757 O O   . SER B 2 55  ? 174.792 180.737 171.305 1.00 79.83  ? 55  SER D O   1 
ATOM   2758 C CB  . SER B 2 55  ? 177.042 180.204 172.800 1.00 82.24  ? 55  SER D CB  1 
ATOM   2759 O OG  . SER B 2 55  ? 178.066 179.856 173.714 1.00 83.72  ? 55  SER D OG  1 
ATOM   2760 N N   . GLY B 2 56  ? 173.337 180.614 173.012 1.00 78.97  ? 56  GLY D N   1 
ATOM   2761 C CA  . GLY B 2 56  ? 172.189 180.828 172.156 1.00 83.88  ? 56  GLY D CA  1 
ATOM   2762 C C   . GLY B 2 56  ? 171.627 182.234 172.211 1.00 86.26  ? 56  GLY D C   1 
ATOM   2763 O O   . GLY B 2 56  ? 171.312 182.820 171.171 1.00 88.64  ? 56  GLY D O   1 
ATOM   2764 N N   . THR B 2 57  ? 171.496 182.788 173.414 1.00 79.43  ? 57  THR D N   1 
ATOM   2765 C CA  . THR B 2 57  ? 170.949 184.124 173.613 1.00 74.40  ? 57  THR D CA  1 
ATOM   2766 C C   . THR B 2 57  ? 171.985 184.992 174.309 1.00 74.81  ? 57  THR D C   1 
ATOM   2767 O O   . THR B 2 57  ? 172.500 184.622 175.369 1.00 82.16  ? 57  THR D O   1 
ATOM   2768 C CB  . THR B 2 57  ? 169.661 184.085 174.439 1.00 73.77  ? 57  THR D CB  1 
ATOM   2769 O OG1 . THR B 2 57  ? 169.987 184.104 175.833 1.00 78.44  ? 57  THR D OG1 1 
ATOM   2770 C CG2 . THR B 2 57  ? 168.861 182.832 174.128 1.00 72.71  ? 57  THR D CG2 1 
ATOM   2771 N N   . ILE B 2 58  ? 172.283 186.144 173.715 1.00 60.43  ? 58  ILE D N   1 
ATOM   2772 C CA  . ILE B 2 58  ? 173.271 187.081 174.234 1.00 60.99  ? 58  ILE D CA  1 
ATOM   2773 C C   . ILE B 2 58  ? 172.613 188.444 174.374 1.00 67.60  ? 58  ILE D C   1 
ATOM   2774 O O   . ILE B 2 58  ? 172.063 188.972 173.401 1.00 74.83  ? 58  ILE D O   1 
ATOM   2775 C CB  . ILE B 2 58  ? 174.503 187.163 173.316 1.00 65.37  ? 58  ILE D CB  1 
ATOM   2776 C CG1 . ILE B 2 58  ? 175.230 185.819 173.273 1.00 67.54  ? 58  ILE D CG1 1 
ATOM   2777 C CG2 . ILE B 2 58  ? 175.426 188.274 173.766 1.00 68.23  ? 58  ILE D CG2 1 
ATOM   2778 C CD1 . ILE B 2 58  ? 176.517 185.850 172.485 1.00 68.69  ? 58  ILE D CD1 1 
ATOM   2779 N N   . TYR B 2 59  ? 172.675 189.017 175.574 1.00 62.83  ? 59  TYR D N   1 
ATOM   2780 C CA  . TYR B 2 59  ? 172.068 190.314 175.840 1.00 58.65  ? 59  TYR D CA  1 
ATOM   2781 C C   . TYR B 2 59  ? 173.103 191.290 176.378 1.00 64.15  ? 59  TYR D C   1 
ATOM   2782 O O   . TYR B 2 59  ? 173.915 190.941 177.241 1.00 73.72  ? 59  TYR D O   1 
ATOM   2783 C CB  . TYR B 2 59  ? 170.908 190.197 176.830 1.00 57.22  ? 59  TYR D CB  1 
ATOM   2784 C CG  . TYR B 2 59  ? 169.728 189.412 176.311 1.00 60.73  ? 59  TYR D CG  1 
ATOM   2785 C CD1 . TYR B 2 59  ? 169.397 189.428 174.966 1.00 68.48  ? 59  TYR D CD1 1 
ATOM   2786 C CD2 . TYR B 2 59  ? 168.938 188.665 177.169 1.00 60.83  ? 59  TYR D CD2 1 
ATOM   2787 C CE1 . TYR B 2 59  ? 168.316 188.715 174.489 1.00 68.91  ? 59  TYR D CE1 1 
ATOM   2788 C CE2 . TYR B 2 59  ? 167.856 187.950 176.702 1.00 62.27  ? 59  TYR D CE2 1 
ATOM   2789 C CZ  . TYR B 2 59  ? 167.549 187.978 175.363 1.00 66.77  ? 59  TYR D CZ  1 
ATOM   2790 O OH  . TYR B 2 59  ? 166.470 187.266 174.895 1.00 68.28  ? 59  TYR D OH  1 
ATOM   2791 N N   . TYR B 2 60  ? 173.066 192.516 175.861 1.00 65.51  ? 60  TYR D N   1 
ATOM   2792 C CA  . TYR B 2 60  ? 173.913 193.603 176.321 1.00 67.93  ? 60  TYR D CA  1 
ATOM   2793 C C   . TYR B 2 60  ? 173.046 194.724 176.880 1.00 69.66  ? 60  TYR D C   1 
ATOM   2794 O O   . TYR B 2 60  ? 171.832 194.765 176.666 1.00 76.72  ? 60  TYR D O   1 
ATOM   2795 C CB  . TYR B 2 60  ? 174.792 194.155 175.193 1.00 69.66  ? 60  TYR D CB  1 
ATOM   2796 C CG  . TYR B 2 60  ? 175.844 193.203 174.678 1.00 68.48  ? 60  TYR D CG  1 
ATOM   2797 C CD1 . TYR B 2 60  ? 175.562 192.322 173.648 1.00 69.01  ? 60  TYR D CD1 1 
ATOM   2798 C CD2 . TYR B 2 60  ? 177.124 193.199 175.209 1.00 67.30  ? 60  TYR D CD2 1 
ATOM   2799 C CE1 . TYR B 2 60  ? 176.522 191.461 173.166 1.00 71.34  ? 60  TYR D CE1 1 
ATOM   2800 C CE2 . TYR B 2 60  ? 178.090 192.339 174.734 1.00 67.03  ? 60  TYR D CE2 1 
ATOM   2801 C CZ  . TYR B 2 60  ? 177.782 191.471 173.714 1.00 72.58  ? 60  TYR D CZ  1 
ATOM   2802 O OH  . TYR B 2 60  ? 178.738 190.608 173.235 1.00 75.89  ? 60  TYR D OH  1 
ATOM   2803 N N   . ALA B 2 61  ? 173.685 195.639 177.602 1.00 77.54  ? 61  ALA D N   1 
ATOM   2804 C CA  . ALA B 2 61  ? 172.992 196.802 178.127 1.00 80.92  ? 61  ALA D CA  1 
ATOM   2805 C C   . ALA B 2 61  ? 172.817 197.856 177.037 1.00 87.76  ? 61  ALA D C   1 
ATOM   2806 O O   . ALA B 2 61  ? 173.431 197.797 175.968 1.00 91.06  ? 61  ALA D O   1 
ATOM   2807 C CB  . ALA B 2 61  ? 173.748 197.386 179.318 1.00 82.36  ? 61  ALA D CB  1 
ATOM   2808 N N   . ASP B 2 62  ? 171.958 198.838 177.321 1.00 102.95 ? 62  ASP D N   1 
ATOM   2809 C CA  . ASP B 2 62  ? 171.678 199.887 176.349 1.00 102.22 ? 62  ASP D CA  1 
ATOM   2810 C C   . ASP B 2 62  ? 172.859 200.825 176.143 1.00 102.58 ? 62  ASP D C   1 
ATOM   2811 O O   . ASP B 2 62  ? 172.930 201.491 175.105 1.00 105.43 ? 62  ASP D O   1 
ATOM   2812 C CB  . ASP B 2 62  ? 170.451 200.689 176.782 1.00 103.01 ? 62  ASP D CB  1 
ATOM   2813 N N   . THR B 2 63  ? 173.782 200.894 177.099 1.00 94.47  ? 63  THR D N   1 
ATOM   2814 C CA  . THR B 2 63  ? 174.933 201.780 177.013 1.00 94.60  ? 63  THR D CA  1 
ATOM   2815 C C   . THR B 2 63  ? 176.226 201.039 176.706 1.00 92.94  ? 63  THR D C   1 
ATOM   2816 O O   . THR B 2 63  ? 177.307 201.618 176.844 1.00 96.13  ? 63  THR D O   1 
ATOM   2817 C CB  . THR B 2 63  ? 175.093 202.567 178.314 1.00 96.84  ? 63  THR D CB  1 
ATOM   2818 O OG1 . THR B 2 63  ? 176.327 203.293 178.286 1.00 98.78  ? 63  THR D OG1 1 
ATOM   2819 C CG2 . THR B 2 63  ? 175.097 201.624 179.506 1.00 93.12  ? 63  THR D CG2 1 
ATOM   2820 N N   . VAL B 2 64  ? 176.146 199.770 176.309 1.00 88.38  ? 64  VAL D N   1 
ATOM   2821 C CA  . VAL B 2 64  ? 177.343 198.976 176.056 1.00 88.47  ? 64  VAL D CA  1 
ATOM   2822 C C   . VAL B 2 64  ? 177.243 198.265 174.712 1.00 92.25  ? 64  VAL D C   1 
ATOM   2823 O O   . VAL B 2 64  ? 178.229 197.694 174.232 1.00 94.98  ? 64  VAL D O   1 
ATOM   2824 C CB  . VAL B 2 64  ? 177.586 197.957 177.186 1.00 94.58  ? 64  VAL D CB  1 
ATOM   2825 C CG1 . VAL B 2 64  ? 177.407 198.597 178.558 1.00 93.04  ? 64  VAL D CG1 1 
ATOM   2826 C CG2 . VAL B 2 64  ? 176.668 196.758 177.027 1.00 94.65  ? 64  VAL D CG2 1 
ATOM   2827 N N   . LYS B 2 65  ? 176.059 198.287 174.099 1.00 87.20  ? 65  LYS D N   1 
ATOM   2828 C CA  . LYS B 2 65  ? 175.831 197.502 172.891 1.00 83.77  ? 65  LYS D CA  1 
ATOM   2829 C C   . LYS B 2 65  ? 176.756 197.949 171.768 1.00 86.17  ? 65  LYS D C   1 
ATOM   2830 O O   . LYS B 2 65  ? 177.033 199.140 171.603 1.00 88.16  ? 65  LYS D O   1 
ATOM   2831 C CB  . LYS B 2 65  ? 174.376 197.615 172.441 1.00 81.64  ? 65  LYS D CB  1 
ATOM   2832 C CG  . LYS B 2 65  ? 173.843 199.033 172.399 1.00 89.42  ? 65  LYS D CG  1 
ATOM   2833 N N   . GLY B 2 66  ? 177.236 196.988 171.003 1.00 92.47  ? 66  GLY D N   1 
ATOM   2834 C CA  . GLY B 2 66  ? 178.160 197.263 169.911 1.00 92.87  ? 66  GLY D CA  1 
ATOM   2835 C C   . GLY B 2 66  ? 179.602 197.363 170.341 1.00 89.41  ? 66  GLY D C   1 
ATOM   2836 O O   . GLY B 2 66  ? 180.480 196.762 169.724 1.00 93.92  ? 66  GLY D O   1 
ATOM   2837 N N   . ARG B 2 67  ? 179.862 198.128 171.400 1.00 91.47  ? 67  ARG D N   1 
ATOM   2838 C CA  . ARG B 2 67  ? 181.224 198.268 171.900 1.00 94.17  ? 67  ARG D CA  1 
ATOM   2839 C C   . ARG B 2 67  ? 181.721 196.968 172.519 1.00 100.35 ? 67  ARG D C   1 
ATOM   2840 O O   . ARG B 2 67  ? 182.822 196.500 172.209 1.00 101.60 ? 67  ARG D O   1 
ATOM   2841 C CB  . ARG B 2 67  ? 181.282 199.391 172.930 1.00 97.98  ? 67  ARG D CB  1 
ATOM   2842 C CG  . ARG B 2 67  ? 181.713 200.727 172.393 1.00 99.12  ? 67  ARG D CG  1 
ATOM   2843 C CD  . ARG B 2 67  ? 181.516 201.782 173.458 1.00 101.91 ? 67  ARG D CD  1 
ATOM   2844 N NE  . ARG B 2 67  ? 182.481 201.616 174.537 1.00 103.64 ? 67  ARG D NE  1 
ATOM   2845 C CZ  . ARG B 2 67  ? 182.250 201.937 175.802 1.00 102.22 ? 67  ARG D CZ  1 
ATOM   2846 N NH1 . ARG B 2 67  ? 181.089 202.441 176.184 1.00 103.15 ? 67  ARG D NH1 1 
ATOM   2847 N NH2 . ARG B 2 67  ? 183.205 201.740 176.706 1.00 97.18  ? 67  ARG D NH2 1 
ATOM   2848 N N   . PHE B 2 68  ? 180.919 196.370 173.395 1.00 107.20 ? 68  PHE D N   1 
ATOM   2849 C CA  . PHE B 2 68  ? 181.361 195.253 174.216 1.00 104.37 ? 68  PHE D CA  1 
ATOM   2850 C C   . PHE B 2 68  ? 181.103 193.952 173.472 1.00 102.96 ? 68  PHE D C   1 
ATOM   2851 O O   . PHE B 2 68  ? 180.095 193.823 172.773 1.00 101.66 ? 68  PHE D O   1 
ATOM   2852 C CB  . PHE B 2 68  ? 180.615 195.227 175.554 1.00 101.11 ? 68  PHE D CB  1 
ATOM   2853 C CG  . PHE B 2 68  ? 180.926 196.389 176.467 1.00 102.54 ? 68  PHE D CG  1 
ATOM   2854 C CD1 . PHE B 2 68  ? 181.605 197.508 176.010 1.00 104.82 ? 68  PHE D CD1 1 
ATOM   2855 C CD2 . PHE B 2 68  ? 180.545 196.346 177.798 1.00 104.31 ? 68  PHE D CD2 1 
ATOM   2856 C CE1 . PHE B 2 68  ? 181.881 198.565 176.856 1.00 106.16 ? 68  PHE D CE1 1 
ATOM   2857 C CE2 . PHE B 2 68  ? 180.823 197.396 178.649 1.00 105.60 ? 68  PHE D CE2 1 
ATOM   2858 C CZ  . PHE B 2 68  ? 181.492 198.507 178.178 1.00 106.47 ? 68  PHE D CZ  1 
ATOM   2859 N N   . THR B 2 69  ? 182.004 192.980 173.623 1.00 94.96  ? 69  THR D N   1 
ATOM   2860 C CA  . THR B 2 69  ? 181.744 191.663 173.040 1.00 91.90  ? 69  THR D CA  1 
ATOM   2861 C C   . THR B 2 69  ? 182.215 190.563 173.980 1.00 92.47  ? 69  THR D C   1 
ATOM   2862 O O   . THR B 2 69  ? 183.386 190.523 174.358 1.00 91.73  ? 69  THR D O   1 
ATOM   2863 C CB  . THR B 2 69  ? 182.388 191.524 171.654 1.00 94.04  ? 69  THR D CB  1 
ATOM   2864 O OG1 . THR B 2 69  ? 182.316 190.159 171.221 1.00 95.29  ? 69  THR D OG1 1 
ATOM   2865 C CG2 . THR B 2 69  ? 183.823 192.007 171.648 1.00 94.02  ? 69  THR D CG2 1 
ATOM   2866 N N   . ILE B 2 70  ? 181.304 189.663 174.346 1.00 83.81  ? 70  ILE D N   1 
ATOM   2867 C CA  . ILE B 2 70  ? 181.546 188.672 175.388 1.00 83.47  ? 70  ILE D CA  1 
ATOM   2868 C C   . ILE B 2 70  ? 181.274 187.281 174.832 1.00 81.62  ? 70  ILE D C   1 
ATOM   2869 O O   . ILE B 2 70  ? 180.248 187.057 174.181 1.00 81.96  ? 70  ILE D O   1 
ATOM   2870 C CB  . ILE B 2 70  ? 180.677 188.941 176.631 1.00 83.94  ? 70  ILE D CB  1 
ATOM   2871 C CG1 . ILE B 2 70  ? 180.638 187.720 177.546 1.00 83.49  ? 70  ILE D CG1 1 
ATOM   2872 C CG2 . ILE B 2 70  ? 179.272 189.339 176.220 1.00 80.22  ? 70  ILE D CG2 1 
ATOM   2873 C CD1 . ILE B 2 70  ? 179.885 187.963 178.825 1.00 81.18  ? 70  ILE D CD1 1 
ATOM   2874 N N   . SER B 2 71  ? 182.192 186.350 175.094 1.00 86.46  ? 71  SER D N   1 
ATOM   2875 C CA  . SER B 2 71  ? 182.071 184.970 174.641 1.00 84.53  ? 71  SER D CA  1 
ATOM   2876 C C   . SER B 2 71  ? 182.567 184.044 175.745 1.00 87.01  ? 71  SER D C   1 
ATOM   2877 O O   . SER B 2 71  ? 183.002 184.490 176.810 1.00 91.38  ? 71  SER D O   1 
ATOM   2878 C CB  . SER B 2 71  ? 182.849 184.746 173.341 1.00 83.18  ? 71  SER D CB  1 
ATOM   2879 O OG  . SER B 2 71  ? 184.133 185.340 173.412 1.00 84.27  ? 71  SER D OG  1 
ATOM   2880 N N   . ARG B 2 72  ? 182.503 182.738 175.490 1.00 85.90  ? 72  ARG D N   1 
ATOM   2881 C CA  . ARG B 2 72  ? 182.986 181.766 176.459 1.00 84.75  ? 72  ARG D CA  1 
ATOM   2882 C C   . ARG B 2 72  ? 183.456 180.508 175.746 1.00 86.57  ? 72  ARG D C   1 
ATOM   2883 O O   . ARG B 2 72  ? 182.910 180.120 174.710 1.00 89.46  ? 72  ARG D O   1 
ATOM   2884 C CB  . ARG B 2 72  ? 181.910 181.414 177.491 1.00 84.07  ? 72  ARG D CB  1 
ATOM   2885 C CG  . ARG B 2 72  ? 180.685 180.712 176.934 1.00 82.00  ? 72  ARG D CG  1 
ATOM   2886 C CD  . ARG B 2 72  ? 179.672 180.474 178.039 1.00 82.59  ? 72  ARG D CD  1 
ATOM   2887 N NE  . ARG B 2 72  ? 178.753 179.386 177.734 1.00 79.84  ? 72  ARG D NE  1 
ATOM   2888 C CZ  . ARG B 2 72  ? 178.026 178.749 178.640 1.00 79.99  ? 72  ARG D CZ  1 
ATOM   2889 N NH1 . ARG B 2 72  ? 178.099 179.057 179.924 1.00 78.90  ? 72  ARG D NH1 1 
ATOM   2890 N NH2 . ARG B 2 72  ? 177.206 177.779 178.249 1.00 80.59  ? 72  ARG D NH2 1 
ATOM   2891 N N   . ASP B 2 73  ? 184.482 179.879 176.313 1.00 96.60  ? 73  ASP D N   1 
ATOM   2892 C CA  . ASP B 2 73  ? 185.000 178.604 175.834 1.00 100.04 ? 73  ASP D CA  1 
ATOM   2893 C C   . ASP B 2 73  ? 184.726 177.547 176.895 1.00 99.99  ? 73  ASP D C   1 
ATOM   2894 O O   . ASP B 2 73  ? 185.163 177.687 178.045 1.00 102.48 ? 73  ASP D O   1 
ATOM   2895 C CB  . ASP B 2 73  ? 186.495 178.695 175.530 1.00 101.48 ? 73  ASP D CB  1 
ATOM   2896 N N   . ASP B 2 74  ? 184.003 176.498 176.507 1.00 96.20  ? 74  ASP D N   1 
ATOM   2897 C CA  . ASP B 2 74  ? 183.558 175.457 177.425 1.00 99.15  ? 74  ASP D CA  1 
ATOM   2898 C C   . ASP B 2 74  ? 184.662 174.462 177.783 1.00 97.42  ? 74  ASP D C   1 
ATOM   2899 O O   . ASP B 2 74  ? 184.887 174.221 178.976 1.00 95.57  ? 74  ASP D O   1 
ATOM   2900 C CB  . ASP B 2 74  ? 182.349 174.719 176.843 1.00 98.55  ? 74  ASP D CB  1 
ATOM   2901 C CG  . ASP B 2 74  ? 181.038 175.382 177.200 1.00 98.23  ? 74  ASP D CG  1 
ATOM   2902 O OD1 . ASP B 2 74  ? 181.068 176.510 177.734 1.00 99.31  ? 74  ASP D OD1 1 
ATOM   2903 O OD2 . ASP B 2 74  ? 179.976 174.775 176.949 1.00 97.78  ? 74  ASP D OD2 1 
ATOM   2904 N N   . PRO B 2 75  ? 185.359 173.847 176.814 1.00 95.11  ? 75  PRO D N   1 
ATOM   2905 C CA  . PRO B 2 75  ? 186.347 172.821 177.194 1.00 91.57  ? 75  PRO D CA  1 
ATOM   2906 C C   . PRO B 2 75  ? 187.434 173.338 178.118 1.00 95.08  ? 75  PRO D C   1 
ATOM   2907 O O   . PRO B 2 75  ? 187.885 172.605 179.007 1.00 98.97  ? 75  PRO D O   1 
ATOM   2908 C CB  . PRO B 2 75  ? 186.916 172.367 175.842 1.00 93.87  ? 75  PRO D CB  1 
ATOM   2909 C CG  . PRO B 2 75  ? 185.860 172.707 174.859 1.00 96.02  ? 75  PRO D CG  1 
ATOM   2910 C CD  . PRO B 2 75  ? 185.302 174.002 175.349 1.00 97.85  ? 75  PRO D CD  1 
ATOM   2911 N N   . LYS B 2 76  ? 187.869 174.582 177.938 1.00 95.84  ? 76  LYS D N   1 
ATOM   2912 C CA  . LYS B 2 76  ? 188.847 175.185 178.831 1.00 96.76  ? 76  LYS D CA  1 
ATOM   2913 C C   . LYS B 2 76  ? 188.208 175.861 180.036 1.00 98.12  ? 76  LYS D C   1 
ATOM   2914 O O   . LYS B 2 76  ? 188.933 176.280 180.945 1.00 98.15  ? 76  LYS D O   1 
ATOM   2915 C CB  . LYS B 2 76  ? 189.708 176.201 178.073 1.00 95.36  ? 76  LYS D CB  1 
ATOM   2916 C CG  . LYS B 2 76  ? 190.631 175.588 177.030 1.00 96.24  ? 76  LYS D CG  1 
ATOM   2917 C CD  . LYS B 2 76  ? 189.961 175.502 175.669 1.00 98.62  ? 76  LYS D CD  1 
ATOM   2918 C CE  . LYS B 2 76  ? 189.743 176.882 175.074 1.00 97.70  ? 76  LYS D CE  1 
ATOM   2919 N NZ  . LYS B 2 76  ? 189.129 176.807 173.720 1.00 94.17  ? 76  LYS D NZ  1 
ATOM   2920 N N   . ASN B 2 77  ? 186.879 175.970 180.062 1.00 96.97  ? 77  ASN D N   1 
ATOM   2921 C CA  . ASN B 2 77  ? 186.142 176.590 181.162 1.00 95.99  ? 77  ASN D CA  1 
ATOM   2922 C C   . ASN B 2 77  ? 186.629 178.018 181.418 1.00 95.07  ? 77  ASN D C   1 
ATOM   2923 O O   . ASN B 2 77  ? 187.164 178.343 182.480 1.00 94.34  ? 77  ASN D O   1 
ATOM   2924 C CB  . ASN B 2 77  ? 186.234 175.737 182.433 1.00 93.59  ? 77  ASN D CB  1 
ATOM   2925 C CG  . ASN B 2 77  ? 185.157 174.673 182.500 1.00 93.67  ? 77  ASN D CG  1 
ATOM   2926 O OD1 . ASN B 2 77  ? 184.267 174.620 181.653 1.00 93.82  ? 77  ASN D OD1 1 
ATOM   2927 N ND2 . ASN B 2 77  ? 185.230 173.820 183.514 1.00 94.96  ? 77  ASN D ND2 1 
ATOM   2928 N N   . THR B 2 78  ? 186.437 178.873 180.416 1.00 96.55  ? 78  THR D N   1 
ATOM   2929 C CA  . THR B 2 78  ? 186.834 180.268 180.526 1.00 95.05  ? 78  THR D CA  1 
ATOM   2930 C C   . THR B 2 78  ? 185.762 181.159 179.916 1.00 100.22 ? 78  THR D C   1 
ATOM   2931 O O   . THR B 2 78  ? 185.026 180.748 179.017 1.00 100.74 ? 78  THR D O   1 
ATOM   2932 C CB  . THR B 2 78  ? 188.185 180.527 179.849 1.00 94.99  ? 78  THR D CB  1 
ATOM   2933 O OG1 . THR B 2 78  ? 188.402 181.938 179.734 1.00 99.66  ? 78  THR D OG1 1 
ATOM   2934 C CG2 . THR B 2 78  ? 188.220 179.892 178.469 1.00 97.35  ? 78  THR D CG2 1 
ATOM   2935 N N   . LEU B 2 79  ? 185.682 182.390 180.421 1.00 94.25  ? 79  LEU D N   1 
ATOM   2936 C CA  . LEU B 2 79  ? 184.678 183.359 179.995 1.00 90.82  ? 79  LEU D CA  1 
ATOM   2937 C C   . LEU B 2 79  ? 185.372 184.678 179.687 1.00 92.41  ? 79  LEU D C   1 
ATOM   2938 O O   . LEU B 2 79  ? 185.959 185.293 180.583 1.00 91.99  ? 79  LEU D O   1 
ATOM   2939 C CB  . LEU B 2 79  ? 183.612 183.541 181.079 1.00 86.87  ? 79  LEU D CB  1 
ATOM   2940 C CG  . LEU B 2 79  ? 182.366 184.373 180.781 1.00 90.97  ? 79  LEU D CG  1 
ATOM   2941 C CD1 . LEU B 2 79  ? 181.244 183.499 180.268 1.00 89.81  ? 79  LEU D CD1 1 
ATOM   2942 C CD2 . LEU B 2 79  ? 181.925 185.094 182.037 1.00 95.52  ? 79  LEU D CD2 1 
ATOM   2943 N N   . PHE B 2 80  ? 185.314 185.109 178.429 1.00 92.46  ? 80  PHE D N   1 
ATOM   2944 C CA  . PHE B 2 80  ? 186.020 186.298 177.976 1.00 92.08  ? 80  PHE D CA  1 
ATOM   2945 C C   . PHE B 2 80  ? 185.053 187.450 177.745 1.00 95.01  ? 80  PHE D C   1 
ATOM   2946 O O   . PHE B 2 80  ? 183.947 187.254 177.230 1.00 98.45  ? 80  PHE D O   1 
ATOM   2947 C CB  . PHE B 2 80  ? 186.792 186.030 176.681 1.00 89.04  ? 80  PHE D CB  1 
ATOM   2948 C CG  . PHE B 2 80  ? 187.754 184.886 176.769 1.00 89.02  ? 80  PHE D CG  1 
ATOM   2949 C CD1 . PHE B 2 80  ? 188.909 184.994 177.521 1.00 92.75  ? 80  PHE D CD1 1 
ATOM   2950 C CD2 . PHE B 2 80  ? 187.516 183.712 176.080 1.00 89.28  ? 80  PHE D CD2 1 
ATOM   2951 C CE1 . PHE B 2 80  ? 189.801 183.948 177.597 1.00 94.20  ? 80  PHE D CE1 1 
ATOM   2952 C CE2 . PHE B 2 80  ? 188.406 182.662 176.151 1.00 93.37  ? 80  PHE D CE2 1 
ATOM   2953 C CZ  . PHE B 2 80  ? 189.551 182.780 176.910 1.00 94.99  ? 80  PHE D CZ  1 
ATOM   2954 N N   . LEU B 2 81  ? 185.485 188.649 178.123 1.00 93.88  ? 81  LEU D N   1 
ATOM   2955 C CA  . LEU B 2 81  ? 184.812 189.896 177.794 1.00 90.79  ? 81  LEU D CA  1 
ATOM   2956 C C   . LEU B 2 81  ? 185.819 190.817 177.121 1.00 93.79  ? 81  LEU D C   1 
ATOM   2957 O O   . LEU B 2 81  ? 186.986 190.867 177.521 1.00 91.63  ? 81  LEU D O   1 
ATOM   2958 C CB  . LEU B 2 81  ? 184.220 190.547 179.047 1.00 92.34  ? 81  LEU D CB  1 
ATOM   2959 C CG  . LEU B 2 81  ? 183.558 191.917 178.930 1.00 92.06  ? 81  LEU D CG  1 
ATOM   2960 C CD1 . LEU B 2 81  ? 182.271 191.957 179.731 1.00 91.37  ? 81  LEU D CD1 1 
ATOM   2961 C CD2 . LEU B 2 81  ? 184.520 192.966 179.444 1.00 94.42  ? 81  LEU D CD2 1 
ATOM   2962 N N   . GLN B 2 82  ? 185.380 191.536 176.090 1.00 104.21 ? 82  GLN D N   1 
ATOM   2963 C CA  . GLN B 2 82  ? 186.284 192.305 175.249 1.00 106.99 ? 82  GLN D CA  1 
ATOM   2964 C C   . GLN B 2 82  ? 185.794 193.741 175.144 1.00 105.69 ? 82  GLN D C   1 
ATOM   2965 O O   . GLN B 2 82  ? 184.621 193.987 174.824 1.00 104.58 ? 82  GLN D O   1 
ATOM   2966 C CB  . GLN B 2 82  ? 186.410 191.675 173.859 1.00 104.97 ? 82  GLN D CB  1 
ATOM   2967 C CG  . GLN B 2 82  ? 187.548 192.227 173.019 1.00 104.89 ? 82  GLN D CG  1 
ATOM   2968 C CD  . GLN B 2 82  ? 188.793 191.365 173.093 1.00 106.55 ? 82  GLN D CD  1 
ATOM   2969 O OE1 . GLN B 2 82  ? 189.140 190.849 174.155 1.00 108.37 ? 82  GLN D OE1 1 
ATOM   2970 N NE2 . GLN B 2 82  ? 189.475 191.208 171.965 1.00 104.87 ? 82  GLN D NE2 1 
ATOM   2971 N N   . MET B 2 83  ? 186.730 194.668 175.364 1.00 105.81 ? 83  MET D N   1 
ATOM   2972 C CA  . MET B 2 83  ? 186.501 196.093 175.554 1.00 106.74 ? 83  MET D CA  1 
ATOM   2973 C C   . MET B 2 83  ? 187.030 196.825 174.330 1.00 104.87 ? 83  MET D C   1 
ATOM   2974 O O   . MET B 2 83  ? 188.222 196.713 174.014 1.00 102.45 ? 83  MET D O   1 
ATOM   2975 C CB  . MET B 2 83  ? 187.252 196.594 176.793 1.00 108.74 ? 83  MET D CB  1 
ATOM   2976 C CG  . MET B 2 83  ? 186.671 196.323 178.186 1.00 107.39 ? 83  MET D CG  1 
ATOM   2977 S SD  . MET B 2 83  ? 185.103 197.075 178.646 1.00 100.32 ? 83  MET D SD  1 
ATOM   2978 C CE  . MET B 2 83  ? 183.966 196.002 177.795 1.00 98.78  ? 83  MET D CE  1 
ATOM   2979 N N   . THR B 2 84  ? 186.166 197.596 173.669 1.00 105.29 ? 84  THR D N   1 
ATOM   2980 C CA  . THR B 2 84  ? 186.551 198.389 172.509 1.00 105.20 ? 84  THR D CA  1 
ATOM   2981 C C   . THR B 2 84  ? 186.120 199.837 172.704 1.00 103.57 ? 84  THR D C   1 
ATOM   2982 O O   . THR B 2 84  ? 185.049 200.105 173.256 1.00 101.39 ? 84  THR D O   1 
ATOM   2983 C CB  . THR B 2 84  ? 185.929 197.839 171.221 1.00 106.48 ? 84  THR D CB  1 
ATOM   2984 O OG1 . THR B 2 84  ? 186.387 196.502 171.004 1.00 105.74 ? 84  THR D OG1 1 
ATOM   2985 C CG2 . THR B 2 84  ? 186.324 198.701 170.029 1.00 107.13 ? 84  THR D CG2 1 
ATOM   2986 N N   . SER B 2 85  ? 186.955 200.764 172.231 1.00 99.35  ? 85  SER D N   1 
ATOM   2987 C CA  . SER B 2 85  ? 186.741 202.206 172.381 1.00 98.45  ? 85  SER D CA  1 
ATOM   2988 C C   . SER B 2 85  ? 186.509 202.567 173.851 1.00 95.26  ? 85  SER D C   1 
ATOM   2989 O O   . SER B 2 85  ? 185.442 203.018 174.265 1.00 93.62  ? 85  SER D O   1 
ATOM   2990 C CB  . SER B 2 85  ? 185.587 202.690 171.500 1.00 100.21 ? 85  SER D CB  1 
ATOM   2991 O OG  . SER B 2 85  ? 184.347 202.221 171.986 1.00 100.05 ? 85  SER D OG  1 
ATOM   2992 N N   . LEU B 2 86  ? 187.564 202.341 174.626 1.00 98.29  ? 86  LEU D N   1 
ATOM   2993 C CA  . LEU B 2 86  ? 187.507 202.476 176.076 1.00 101.24 ? 86  LEU D CA  1 
ATOM   2994 C C   . LEU B 2 86  ? 187.383 203.946 176.465 1.00 100.33 ? 86  LEU D C   1 
ATOM   2995 O O   . LEU B 2 86  ? 188.153 204.787 175.988 1.00 100.02 ? 86  LEU D O   1 
ATOM   2996 C CB  . LEU B 2 86  ? 188.758 201.843 176.676 1.00 99.60  ? 86  LEU D CB  1 
ATOM   2997 C CG  . LEU B 2 86  ? 188.904 201.955 178.189 1.00 100.75 ? 86  LEU D CG  1 
ATOM   2998 C CD1 . LEU B 2 86  ? 187.783 201.226 178.881 1.00 99.97  ? 86  LEU D CD1 1 
ATOM   2999 C CD2 . LEU B 2 86  ? 190.231 201.383 178.616 1.00 101.96 ? 86  LEU D CD2 1 
ATOM   3000 N N   . ARG B 2 87  ? 186.419 204.259 177.331 1.00 103.15 ? 87  ARG D N   1 
ATOM   3001 C CA  . ARG B 2 87  ? 186.091 205.638 177.669 1.00 103.47 ? 87  ARG D CA  1 
ATOM   3002 C C   . ARG B 2 87  ? 186.109 205.826 179.183 1.00 104.79 ? 87  ARG D C   1 
ATOM   3003 O O   . ARG B 2 87  ? 186.284 204.877 179.950 1.00 106.32 ? 87  ARG D O   1 
ATOM   3004 C CB  . ARG B 2 87  ? 184.731 206.043 177.075 1.00 102.39 ? 87  ARG D CB  1 
ATOM   3005 C CG  . ARG B 2 87  ? 184.653 206.078 175.555 1.00 103.65 ? 87  ARG D CG  1 
ATOM   3006 C CD  . ARG B 2 87  ? 183.240 206.395 175.084 1.00 103.02 ? 87  ARG D CD  1 
ATOM   3007 N NE  . ARG B 2 87  ? 182.795 207.726 175.484 1.00 108.49 ? 87  ARG D NE  1 
ATOM   3008 C CZ  . ARG B 2 87  ? 181.573 208.209 175.303 1.00 109.31 ? 87  ARG D CZ  1 
ATOM   3009 N NH1 . ARG B 2 87  ? 180.618 207.488 174.739 1.00 107.37 ? 87  ARG D NH1 1 
ATOM   3010 N NH2 . ARG B 2 87  ? 181.301 209.448 175.701 1.00 107.59 ? 87  ARG D NH2 1 
ATOM   3011 N N   . SER B 2 88  ? 185.925 207.080 179.608 1.00 96.83  ? 88  SER D N   1 
ATOM   3012 C CA  . SER B 2 88  ? 186.077 207.462 181.006 1.00 94.68  ? 88  SER D CA  1 
ATOM   3013 C C   . SER B 2 88  ? 184.869 207.129 181.870 1.00 94.13  ? 88  SER D C   1 
ATOM   3014 O O   . SER B 2 88  ? 184.949 207.282 183.093 1.00 91.27  ? 88  SER D O   1 
ATOM   3015 C CB  . SER B 2 88  ? 186.367 208.960 181.110 1.00 93.44  ? 88  SER D CB  1 
ATOM   3016 O OG  . SER B 2 88  ? 185.216 209.722 180.791 1.00 92.32  ? 88  SER D OG  1 
ATOM   3017 N N   . GLU B 2 89  ? 183.760 206.684 181.282 1.00 102.98 ? 89  GLU D N   1 
ATOM   3018 C CA  . GLU B 2 89  ? 182.558 206.419 182.061 1.00 101.37 ? 89  GLU D CA  1 
ATOM   3019 C C   . GLU B 2 89  ? 182.521 205.015 182.650 1.00 97.63  ? 89  GLU D C   1 
ATOM   3020 O O   . GLU B 2 89  ? 181.614 204.717 183.434 1.00 101.46 ? 89  GLU D O   1 
ATOM   3021 C CB  . GLU B 2 89  ? 181.313 206.645 181.197 1.00 104.74 ? 89  GLU D CB  1 
ATOM   3022 C CG  . GLU B 2 89  ? 180.093 207.138 181.964 1.00 105.39 ? 89  GLU D CG  1 
ATOM   3023 C CD  . GLU B 2 89  ? 179.135 206.018 182.326 1.00 107.46 ? 89  GLU D CD  1 
ATOM   3024 O OE1 . GLU B 2 89  ? 178.774 205.228 181.429 1.00 107.40 ? 89  GLU D OE1 1 
ATOM   3025 O OE2 . GLU B 2 89  ? 178.746 205.926 183.510 1.00 106.08 ? 89  GLU D OE2 1 
ATOM   3026 N N   . ASP B 2 90  ? 183.501 204.176 182.285 1.00 99.51  ? 90  ASP D N   1 
ATOM   3027 C CA  . ASP B 2 90  ? 183.508 202.746 182.703 1.00 105.65 ? 90  ASP D CA  1 
ATOM   3028 C C   . ASP B 2 90  ? 184.554 202.437 183.783 1.00 106.25 ? 90  ASP D C   1 
ATOM   3029 O O   . ASP B 2 90  ? 184.795 201.239 184.020 1.00 107.92 ? 90  ASP D O   1 
ATOM   3030 C CB  . ASP B 2 90  ? 183.894 201.855 181.522 1.00 107.51 ? 90  ASP D CB  1 
ATOM   3031 C CG  . ASP B 2 90  ? 185.317 202.088 181.043 1.00 111.52 ? 90  ASP D CG  1 
ATOM   3032 O OD1 . ASP B 2 90  ? 186.056 202.815 181.734 1.00 111.72 ? 90  ASP D OD1 1 
ATOM   3033 O OD2 . ASP B 2 90  ? 185.675 201.532 179.987 1.00 110.79 ? 90  ASP D OD2 1 
ATOM   3034 N N   . THR B 2 91  ? 185.156 203.447 184.411 1.00 97.56  ? 91  THR D N   1 
ATOM   3035 C CA  . THR B 2 91  ? 186.212 203.200 185.390 1.00 95.45  ? 91  THR D CA  1 
ATOM   3036 C C   . THR B 2 91  ? 185.453 202.639 186.584 1.00 96.80  ? 91  THR D C   1 
ATOM   3037 O O   . THR B 2 91  ? 184.736 203.362 187.280 1.00 98.97  ? 91  THR D O   1 
ATOM   3038 C CB  . THR B 2 91  ? 186.973 204.475 185.735 1.00 99.97  ? 91  THR D CB  1 
ATOM   3039 O OG1 . THR B 2 91  ? 188.011 204.676 184.770 1.00 101.75 ? 91  THR D OG1 1 
ATOM   3040 C CG2 . THR B 2 91  ? 187.623 204.367 187.108 1.00 99.12  ? 91  THR D CG2 1 
ATOM   3041 N N   . ALA B 2 92  ? 185.571 201.334 186.794 1.00 99.63  ? 92  ALA D N   1 
ATOM   3042 C CA  . ALA B 2 92  ? 184.772 200.644 187.803 1.00 101.01 ? 92  ALA D CA  1 
ATOM   3043 C C   . ALA B 2 92  ? 185.352 199.249 187.998 1.00 101.84 ? 92  ALA D C   1 
ATOM   3044 O O   . ALA B 2 92  ? 186.379 198.895 187.411 1.00 105.14 ? 92  ALA D O   1 
ATOM   3045 C CB  . ALA B 2 92  ? 183.301 200.590 187.395 1.00 99.11  ? 92  ALA D CB  1 
ATOM   3046 N N   . MET B 2 93  ? 184.682 198.449 188.827 1.00 93.58  ? 93  MET D N   1 
ATOM   3047 C CA  . MET B 2 93  ? 185.151 197.105 189.133 1.00 92.28  ? 93  MET D CA  1 
ATOM   3048 C C   . MET B 2 93  ? 184.057 196.102 188.781 1.00 94.61  ? 93  MET D C   1 
ATOM   3049 O O   . MET B 2 93  ? 182.888 196.290 189.133 1.00 95.80  ? 93  MET D O   1 
ATOM   3050 C CB  . MET B 2 93  ? 185.617 197.030 190.599 1.00 91.19  ? 93  MET D CB  1 
ATOM   3051 C CG  . MET B 2 93  ? 186.105 195.677 191.095 1.00 97.68  ? 93  MET D CG  1 
ATOM   3052 S SD  . MET B 2 93  ? 186.569 195.785 192.843 1.00 106.15 ? 93  MET D SD  1 
ATOM   3053 C CE  . MET B 2 93  ? 185.213 194.981 193.674 1.00 93.59  ? 93  MET D CE  1 
ATOM   3054 N N   . TYR B 2 94  ? 184.443 195.064 188.045 1.00 88.46  ? 94  TYR D N   1 
ATOM   3055 C CA  . TYR B 2 94  ? 183.528 194.148 187.383 1.00 85.02  ? 94  TYR D CA  1 
ATOM   3056 C C   . TYR B 2 94  ? 183.434 192.823 188.129 1.00 86.84  ? 94  TYR D C   1 
ATOM   3057 O O   . TYR B 2 94  ? 184.405 192.353 188.733 1.00 93.40  ? 94  TYR D O   1 
ATOM   3058 C CB  . TYR B 2 94  ? 183.974 193.887 185.943 1.00 81.80  ? 94  TYR D CB  1 
ATOM   3059 C CG  . TYR B 2 94  ? 184.003 195.108 185.057 1.00 83.80  ? 94  TYR D CG  1 
ATOM   3060 C CD1 . TYR B 2 94  ? 185.124 195.921 185.003 1.00 85.76  ? 94  TYR D CD1 1 
ATOM   3061 C CD2 . TYR B 2 94  ? 182.916 195.438 184.262 1.00 84.00  ? 94  TYR D CD2 1 
ATOM   3062 C CE1 . TYR B 2 94  ? 185.160 197.029 184.195 1.00 83.42  ? 94  TYR D CE1 1 
ATOM   3063 C CE2 . TYR B 2 94  ? 182.943 196.546 183.450 1.00 85.99  ? 94  TYR D CE2 1 
ATOM   3064 C CZ  . TYR B 2 94  ? 184.068 197.338 183.422 1.00 84.29  ? 94  TYR D CZ  1 
ATOM   3065 O OH  . TYR B 2 94  ? 184.099 198.446 182.612 1.00 88.45  ? 94  TYR D OH  1 
ATOM   3066 N N   . TYR B 2 95  ? 182.243 192.223 188.066 1.00 66.99  ? 95  TYR D N   1 
ATOM   3067 C CA  . TYR B 2 95  ? 181.920 190.951 188.692 1.00 70.46  ? 95  TYR D CA  1 
ATOM   3068 C C   . TYR B 2 95  ? 181.357 190.005 187.644 1.00 75.24  ? 95  TYR D C   1 
ATOM   3069 O O   . TYR B 2 95  ? 180.667 190.430 186.711 1.00 71.98  ? 95  TYR D O   1 
ATOM   3070 C CB  . TYR B 2 95  ? 180.863 191.101 189.797 1.00 71.34  ? 95  TYR D CB  1 
ATOM   3071 C CG  . TYR B 2 95  ? 181.281 191.862 191.023 1.00 71.25  ? 95  TYR D CG  1 
ATOM   3072 C CD1 . TYR B 2 95  ? 182.589 192.266 191.207 1.00 75.09  ? 95  TYR D CD1 1 
ATOM   3073 C CD2 . TYR B 2 95  ? 180.350 192.196 191.991 1.00 72.29  ? 95  TYR D CD2 1 
ATOM   3074 C CE1 . TYR B 2 95  ? 182.960 192.963 192.330 1.00 70.88  ? 95  TYR D CE1 1 
ATOM   3075 C CE2 . TYR B 2 95  ? 180.714 192.898 193.110 1.00 78.22  ? 95  TYR D CE2 1 
ATOM   3076 C CZ  . TYR B 2 95  ? 182.020 193.279 193.278 1.00 73.21  ? 95  TYR D CZ  1 
ATOM   3077 O OH  . TYR B 2 95  ? 182.377 193.979 194.402 1.00 72.81  ? 95  TYR D OH  1 
ATOM   3078 N N   . CYS B 2 96  ? 181.628 188.716 187.829 1.00 76.79  ? 96  CYS D N   1 
ATOM   3079 C CA  . CYS B 2 96  ? 181.000 187.652 187.063 1.00 71.56  ? 96  CYS D CA  1 
ATOM   3080 C C   . CYS B 2 96  ? 180.106 186.839 187.988 1.00 61.49  ? 96  CYS D C   1 
ATOM   3081 O O   . CYS B 2 96  ? 180.497 186.508 189.112 1.00 73.16  ? 96  CYS D O   1 
ATOM   3082 C CB  . CYS B 2 96  ? 182.041 186.745 186.399 1.00 72.06  ? 96  CYS D CB  1 
ATOM   3083 S SG  . CYS B 2 96  ? 183.164 185.898 187.530 1.00 83.53  ? 96  CYS D SG  1 
ATOM   3084 N N   . VAL B 2 97  ? 178.903 186.531 187.519 1.00 41.88  ? 97  VAL D N   1 
ATOM   3085 C CA  . VAL B 2 97  ? 177.894 185.854 188.321 1.00 46.64  ? 97  VAL D CA  1 
ATOM   3086 C C   . VAL B 2 97  ? 177.393 184.641 187.555 1.00 56.83  ? 97  VAL D C   1 
ATOM   3087 O O   . VAL B 2 97  ? 177.100 184.736 186.359 1.00 68.13  ? 97  VAL D O   1 
ATOM   3088 C CB  . VAL B 2 97  ? 176.721 186.789 188.666 1.00 60.46  ? 97  VAL D CB  1 
ATOM   3089 C CG1 . VAL B 2 97  ? 175.723 186.075 189.562 1.00 64.99  ? 97  VAL D CG1 1 
ATOM   3090 C CG2 . VAL B 2 97  ? 177.230 188.063 189.323 1.00 62.73  ? 97  VAL D CG2 1 
ATOM   3091 N N   . ARG B 2 98  ? 177.299 183.507 188.236 1.00 62.65  ? 98  ARG D N   1 
ATOM   3092 C CA  . ARG B 2 98  ? 176.716 182.307 187.659 1.00 61.54  ? 98  ARG D CA  1 
ATOM   3093 C C   . ARG B 2 98  ? 175.221 182.268 187.945 1.00 56.96  ? 98  ARG D C   1 
ATOM   3094 O O   . ARG B 2 98  ? 174.745 182.837 188.930 1.00 66.16  ? 98  ARG D O   1 
ATOM   3095 C CB  . ARG B 2 98  ? 177.398 181.057 188.217 1.00 63.72  ? 98  ARG D CB  1 
ATOM   3096 C CG  . ARG B 2 98  ? 176.840 180.594 189.548 1.00 65.42  ? 98  ARG D CG  1 
ATOM   3097 C CD  . ARG B 2 98  ? 177.828 179.718 190.295 1.00 69.31  ? 98  ARG D CD  1 
ATOM   3098 N NE  . ARG B 2 98  ? 177.169 178.898 191.303 1.00 71.69  ? 98  ARG D NE  1 
ATOM   3099 C CZ  . ARG B 2 98  ? 177.035 177.582 191.228 1.00 72.24  ? 98  ARG D CZ  1 
ATOM   3100 N NH1 . ARG B 2 98  ? 177.533 176.893 190.215 1.00 71.36  ? 98  ARG D NH1 1 
ATOM   3101 N NH2 . ARG B 2 98  ? 176.395 176.939 192.200 1.00 72.96  ? 98  ARG D NH2 1 
ATOM   3102 N N   . SER B 2 99  ? 174.478 181.603 187.065 1.00 56.65  ? 99  SER D N   1 
ATOM   3103 C CA  . SER B 2 99  ? 173.035 181.534 187.231 1.00 57.12  ? 99  SER D CA  1 
ATOM   3104 C C   . SER B 2 99  ? 172.488 180.365 186.429 1.00 62.87  ? 99  SER D C   1 
ATOM   3105 O O   . SER B 2 99  ? 172.928 180.119 185.306 1.00 72.70  ? 99  SER D O   1 
ATOM   3106 C CB  . SER B 2 99  ? 172.365 182.835 186.781 1.00 65.49  ? 99  SER D CB  1 
ATOM   3107 O OG  . SER B 2 99  ? 172.052 182.788 185.402 1.00 66.14  ? 99  SER D OG  1 
ATOM   3108 N N   . ILE B 2 100 ? 171.524 179.657 187.010 1.00 60.77  ? 100 ILE D N   1 
ATOM   3109 C CA  . ILE B 2 100 ? 170.828 178.568 186.338 1.00 60.43  ? 100 ILE D CA  1 
ATOM   3110 C C   . ILE B 2 100 ? 169.332 178.820 186.448 1.00 65.45  ? 100 ILE D C   1 
ATOM   3111 O O   . ILE B 2 100 ? 168.856 179.361 187.453 1.00 72.36  ? 100 ILE D O   1 
ATOM   3112 C CB  . ILE B 2 100 ? 171.210 177.192 186.925 1.00 66.54  ? 100 ILE D CB  1 
ATOM   3113 C CG1 . ILE B 2 100 ? 170.819 176.069 185.963 1.00 69.10  ? 100 ILE D CG1 1 
ATOM   3114 C CG2 . ILE B 2 100 ? 170.596 176.991 188.304 1.00 66.80  ? 100 ILE D CG2 1 
ATOM   3115 C CD1 . ILE B 2 100 ? 171.628 174.806 186.147 1.00 67.37  ? 100 ILE D CD1 1 
ATOM   3116 N N   . TYR B 2 101 ? 168.594 178.463 185.401 1.00 65.22  ? 101 TYR D N   1 
ATOM   3117 C CA  . TYR B 2 101 ? 167.167 178.759 185.317 1.00 69.57  ? 101 TYR D CA  1 
ATOM   3118 C C   . TYR B 2 101 ? 166.391 177.474 185.065 1.00 70.81  ? 101 TYR D C   1 
ATOM   3119 O O   . TYR B 2 101 ? 166.418 176.931 183.955 1.00 74.82  ? 101 TYR D O   1 
ATOM   3120 C CB  . TYR B 2 101 ? 166.886 179.785 184.222 1.00 66.93  ? 101 TYR D CB  1 
ATOM   3121 C CG  . TYR B 2 101 ? 167.564 181.117 184.434 1.00 63.84  ? 101 TYR D CG  1 
ATOM   3122 C CD1 . TYR B 2 101 ? 167.150 181.975 185.439 1.00 67.52  ? 101 TYR D CD1 1 
ATOM   3123 C CD2 . TYR B 2 101 ? 168.617 181.517 183.626 1.00 64.51  ? 101 TYR D CD2 1 
ATOM   3124 C CE1 . TYR B 2 101 ? 167.767 183.193 185.634 1.00 69.77  ? 101 TYR D CE1 1 
ATOM   3125 C CE2 . TYR B 2 101 ? 169.238 182.731 183.815 1.00 66.32  ? 101 TYR D CE2 1 
ATOM   3126 C CZ  . TYR B 2 101 ? 168.811 183.564 184.821 1.00 66.56  ? 101 TYR D CZ  1 
ATOM   3127 O OH  . TYR B 2 101 ? 169.429 184.776 185.010 1.00 68.67  ? 101 TYR D OH  1 
ATOM   3128 N N   . TYR B 2 102 ? 165.703 176.996 186.095 1.00 70.45  ? 102 TYR D N   1 
ATOM   3129 C CA  . TYR B 2 102 ? 164.700 175.948 185.964 1.00 66.06  ? 102 TYR D CA  1 
ATOM   3130 C C   . TYR B 2 102 ? 163.756 176.079 187.151 1.00 70.49  ? 102 TYR D C   1 
ATOM   3131 O O   . TYR B 2 102 ? 163.919 176.960 187.998 1.00 76.03  ? 102 TYR D O   1 
ATOM   3132 C CB  . TYR B 2 102 ? 165.334 174.556 185.880 1.00 62.29  ? 102 TYR D CB  1 
ATOM   3133 C CG  . TYR B 2 102 ? 166.290 174.216 186.997 1.00 63.26  ? 102 TYR D CG  1 
ATOM   3134 C CD1 . TYR B 2 102 ? 165.844 173.592 188.152 1.00 67.94  ? 102 TYR D CD1 1 
ATOM   3135 C CD2 . TYR B 2 102 ? 167.643 174.494 186.887 1.00 69.26  ? 102 TYR D CD2 1 
ATOM   3136 C CE1 . TYR B 2 102 ? 166.716 173.270 189.170 1.00 71.08  ? 102 TYR D CE1 1 
ATOM   3137 C CE2 . TYR B 2 102 ? 168.520 174.174 187.901 1.00 70.58  ? 102 TYR D CE2 1 
ATOM   3138 C CZ  . TYR B 2 102 ? 168.052 173.563 189.039 1.00 70.14  ? 102 TYR D CZ  1 
ATOM   3139 O OH  . TYR B 2 102 ? 168.926 173.246 190.052 1.00 70.11  ? 102 TYR D OH  1 
ATOM   3140 N N   . TYR B 2 103 ? 162.754 175.206 187.201 1.00 66.84  ? 103 TYR D N   1 
ATOM   3141 C CA  . TYR B 2 103 ? 161.765 175.287 188.268 1.00 63.21  ? 103 TYR D CA  1 
ATOM   3142 C C   . TYR B 2 103 ? 162.430 175.067 189.620 1.00 64.39  ? 103 TYR D C   1 
ATOM   3143 O O   . TYR B 2 103 ? 163.051 174.026 189.856 1.00 73.89  ? 103 TYR D O   1 
ATOM   3144 C CB  . TYR B 2 103 ? 160.658 174.262 188.045 1.00 61.95  ? 103 TYR D CB  1 
ATOM   3145 C CG  . TYR B 2 103 ? 159.608 174.270 189.129 1.00 59.70  ? 103 TYR D CG  1 
ATOM   3146 C CD1 . TYR B 2 103 ? 158.652 175.272 189.186 1.00 60.97  ? 103 TYR D CD1 1 
ATOM   3147 C CD2 . TYR B 2 103 ? 159.573 173.278 190.097 1.00 66.37  ? 103 TYR D CD2 1 
ATOM   3148 C CE1 . TYR B 2 103 ? 157.691 175.287 190.173 1.00 68.49  ? 103 TYR D CE1 1 
ATOM   3149 C CE2 . TYR B 2 103 ? 158.615 173.284 191.090 1.00 67.45  ? 103 TYR D CE2 1 
ATOM   3150 C CZ  . TYR B 2 103 ? 157.677 174.291 191.123 1.00 70.13  ? 103 TYR D CZ  1 
ATOM   3151 O OH  . TYR B 2 103 ? 156.721 174.301 192.111 1.00 69.75  ? 103 TYR D OH  1 
ATOM   3152 N N   . GLY B 2 104 ? 162.300 176.050 190.506 1.00 61.30  ? 104 GLY D N   1 
ATOM   3153 C CA  . GLY B 2 104 ? 162.911 175.972 191.815 1.00 64.36  ? 104 GLY D CA  1 
ATOM   3154 C C   . GLY B 2 104 ? 164.357 176.402 191.878 1.00 62.37  ? 104 GLY D C   1 
ATOM   3155 O O   . GLY B 2 104 ? 164.991 176.230 192.924 1.00 68.70  ? 104 GLY D O   1 
ATOM   3156 N N   . SER B 2 105 ? 164.902 176.954 190.798 1.00 62.17  ? 105 SER D N   1 
ATOM   3157 C CA  . SER B 2 105 ? 166.297 177.358 190.789 1.00 67.40  ? 105 SER D CA  1 
ATOM   3158 C C   . SER B 2 105 ? 166.490 178.642 191.593 1.00 69.85  ? 105 SER D C   1 
ATOM   3159 O O   . SER B 2 105 ? 165.538 179.343 191.946 1.00 72.62  ? 105 SER D O   1 
ATOM   3160 C CB  . SER B 2 105 ? 166.790 177.549 189.356 1.00 75.29  ? 105 SER D CB  1 
ATOM   3161 O OG  . SER B 2 105 ? 165.985 178.483 188.659 1.00 80.78  ? 105 SER D OG  1 
ATOM   3162 N N   . SER B 2 106 ? 167.753 178.946 191.881 1.00 68.53  ? 106 SER D N   1 
ATOM   3163 C CA  . SER B 2 106 ? 168.138 180.134 192.641 1.00 69.53  ? 106 SER D CA  1 
ATOM   3164 C C   . SER B 2 106 ? 169.207 180.883 191.858 1.00 68.58  ? 106 SER D C   1 
ATOM   3165 O O   . SER B 2 106 ? 170.407 180.738 192.125 1.00 71.15  ? 106 SER D O   1 
ATOM   3166 C CB  . SER B 2 106 ? 168.634 179.758 194.038 1.00 67.84  ? 106 SER D CB  1 
ATOM   3167 O OG  . SER B 2 106 ? 169.854 179.042 193.970 1.00 69.66  ? 106 SER D OG  1 
ATOM   3168 N N   . PRO B 2 107 ? 168.807 181.689 190.878 1.00 63.14  ? 107 PRO D N   1 
ATOM   3169 C CA  . PRO B 2 107 ? 169.790 182.426 190.079 1.00 62.02  ? 107 PRO D CA  1 
ATOM   3170 C C   . PRO B 2 107 ? 170.535 183.458 190.911 1.00 64.11  ? 107 PRO D C   1 
ATOM   3171 O O   . PRO B 2 107 ? 170.086 183.883 191.976 1.00 73.44  ? 107 PRO D O   1 
ATOM   3172 C CB  . PRO B 2 107 ? 168.948 183.103 188.992 1.00 64.49  ? 107 PRO D CB  1 
ATOM   3173 C CG  . PRO B 2 107 ? 167.545 182.997 189.439 1.00 69.69  ? 107 PRO D CG  1 
ATOM   3174 C CD  . PRO B 2 107 ? 167.440 181.832 190.357 1.00 65.69  ? 107 PRO D CD  1 
ATOM   3175 N N   . PHE B 2 108 ? 171.699 183.855 190.392 1.00 61.20  ? 108 PHE D N   1 
ATOM   3176 C CA  . PHE B 2 108 ? 172.607 184.778 191.075 1.00 60.09  ? 108 PHE D CA  1 
ATOM   3177 C C   . PHE B 2 108 ? 173.078 184.188 192.403 1.00 66.50  ? 108 PHE D C   1 
ATOM   3178 O O   . PHE B 2 108 ? 173.056 184.841 193.447 1.00 68.66  ? 108 PHE D O   1 
ATOM   3179 C CB  . PHE B 2 108 ? 171.957 186.149 191.277 1.00 62.66  ? 108 PHE D CB  1 
ATOM   3180 C CG  . PHE B 2 108 ? 171.793 186.937 190.010 1.00 65.15  ? 108 PHE D CG  1 
ATOM   3181 C CD1 . PHE B 2 108 ? 170.754 186.667 189.139 1.00 60.45  ? 108 PHE D CD1 1 
ATOM   3182 C CD2 . PHE B 2 108 ? 172.677 187.954 189.693 1.00 64.20  ? 108 PHE D CD2 1 
ATOM   3183 C CE1 . PHE B 2 108 ? 170.604 187.391 187.978 1.00 60.32  ? 108 PHE D CE1 1 
ATOM   3184 C CE2 . PHE B 2 108 ? 172.530 188.680 188.532 1.00 55.74  ? 108 PHE D CE2 1 
ATOM   3185 C CZ  . PHE B 2 108 ? 171.494 188.399 187.675 1.00 58.38  ? 108 PHE D CZ  1 
ATOM   3186 N N   . ASP B 2 109 ? 173.522 182.932 192.349 1.00 68.72  ? 109 ASP D N   1 
ATOM   3187 C CA  . ASP B 2 109 ? 173.871 182.202 193.562 1.00 64.00  ? 109 ASP D CA  1 
ATOM   3188 C C   . ASP B 2 109 ? 175.257 182.585 194.068 1.00 67.68  ? 109 ASP D C   1 
ATOM   3189 O O   . ASP B 2 109 ? 175.406 183.065 195.197 1.00 74.37  ? 109 ASP D O   1 
ATOM   3190 C CB  . ASP B 2 109 ? 173.789 180.695 193.306 1.00 65.59  ? 109 ASP D CB  1 
ATOM   3191 C CG  . ASP B 2 109 ? 173.459 179.909 194.557 1.00 75.09  ? 109 ASP D CG  1 
ATOM   3192 O OD1 . ASP B 2 109 ? 174.073 180.179 195.611 1.00 77.97  ? 109 ASP D OD1 1 
ATOM   3193 O OD2 . ASP B 2 109 ? 172.584 179.021 194.488 1.00 79.69  ? 109 ASP D OD2 1 
ATOM   3194 N N   . PHE B 2 110 ? 176.283 182.381 193.249 1.00 57.96  ? 110 PHE D N   1 
ATOM   3195 C CA  . PHE B 2 110 ? 177.661 182.618 193.650 1.00 59.57  ? 110 PHE D CA  1 
ATOM   3196 C C   . PHE B 2 110 ? 178.235 183.795 192.875 1.00 62.74  ? 110 PHE D C   1 
ATOM   3197 O O   . PHE B 2 110 ? 177.939 183.975 191.690 1.00 72.07  ? 110 PHE D O   1 
ATOM   3198 C CB  . PHE B 2 110 ? 178.520 181.373 193.421 1.00 65.14  ? 110 PHE D CB  1 
ATOM   3199 C CG  . PHE B 2 110 ? 179.828 181.400 194.150 1.00 69.66  ? 110 PHE D CG  1 
ATOM   3200 C CD1 . PHE B 2 110 ? 179.864 181.481 195.530 1.00 68.99  ? 110 PHE D CD1 1 
ATOM   3201 C CD2 . PHE B 2 110 ? 181.023 181.342 193.458 1.00 71.19  ? 110 PHE D CD2 1 
ATOM   3202 C CE1 . PHE B 2 110 ? 181.066 181.505 196.205 1.00 70.09  ? 110 PHE D CE1 1 
ATOM   3203 C CE2 . PHE B 2 110 ? 182.228 181.366 194.127 1.00 70.59  ? 110 PHE D CE2 1 
ATOM   3204 C CZ  . PHE B 2 110 ? 182.250 181.447 195.502 1.00 70.28  ? 110 PHE D CZ  1 
ATOM   3205 N N   . TRP B 2 111 ? 179.056 184.594 193.552 1.00 52.65  ? 111 TRP D N   1 
ATOM   3206 C CA  . TRP B 2 111 ? 179.652 185.792 192.978 1.00 54.45  ? 111 TRP D CA  1 
ATOM   3207 C C   . TRP B 2 111 ? 181.163 185.728 193.127 1.00 43.55  ? 111 TRP D C   1 
ATOM   3208 O O   . TRP B 2 111 ? 181.671 185.442 194.215 1.00 52.75  ? 111 TRP D O   1 
ATOM   3209 C CB  . TRP B 2 111 ? 179.120 187.055 193.659 1.00 67.13  ? 111 TRP D CB  1 
ATOM   3210 C CG  . TRP B 2 111 ? 177.694 187.388 193.339 1.00 68.91  ? 111 TRP D CG  1 
ATOM   3211 C CD1 . TRP B 2 111 ? 176.600 186.600 193.539 1.00 72.90  ? 111 TRP D CD1 1 
ATOM   3212 C CD2 . TRP B 2 111 ? 177.210 188.610 192.773 1.00 51.29  ? 111 TRP D CD2 1 
ATOM   3213 N NE1 . TRP B 2 111 ? 175.465 187.253 193.125 1.00 64.82  ? 111 TRP D NE1 1 
ATOM   3214 C CE2 . TRP B 2 111 ? 175.814 188.490 192.652 1.00 50.54  ? 111 TRP D CE2 1 
ATOM   3215 C CE3 . TRP B 2 111 ? 177.824 189.791 192.350 1.00 50.68  ? 111 TRP D CE3 1 
ATOM   3216 C CZ2 . TRP B 2 111 ? 175.022 189.505 192.129 1.00 56.56  ? 111 TRP D CZ2 1 
ATOM   3217 C CZ3 . TRP B 2 111 ? 177.038 190.797 191.834 1.00 65.74  ? 111 TRP D CZ3 1 
ATOM   3218 C CH2 . TRP B 2 111 ? 175.652 190.649 191.726 1.00 69.00  ? 111 TRP D CH2 1 
ATOM   3219 N N   . GLY B 2 112 ? 181.876 186.002 192.041 1.00 46.02  ? 112 GLY D N   1 
ATOM   3220 C CA  . GLY B 2 112 ? 183.317 186.095 192.090 1.00 55.15  ? 112 GLY D CA  1 
ATOM   3221 C C   . GLY B 2 112 ? 183.780 187.393 192.718 1.00 60.81  ? 112 GLY D C   1 
ATOM   3222 O O   . GLY B 2 112 ? 182.996 188.281 193.050 1.00 69.07  ? 112 GLY D O   1 
ATOM   3223 N N   . GLN B 2 113 ? 185.099 187.502 192.876 1.00 76.15  ? 113 GLN D N   1 
ATOM   3224 C CA  . GLN B 2 113 ? 185.677 188.680 193.513 1.00 79.16  ? 113 GLN D CA  1 
ATOM   3225 C C   . GLN B 2 113 ? 185.641 189.907 192.611 1.00 82.27  ? 113 GLN D C   1 
ATOM   3226 O O   . GLN B 2 113 ? 185.467 191.026 193.104 1.00 85.23  ? 113 GLN D O   1 
ATOM   3227 C CB  . GLN B 2 113 ? 187.116 188.393 193.941 1.00 80.91  ? 113 GLN D CB  1 
ATOM   3228 C CG  . GLN B 2 113 ? 187.286 187.099 194.711 1.00 81.51  ? 113 GLN D CG  1 
ATOM   3229 C CD  . GLN B 2 113 ? 188.551 186.362 194.328 1.00 84.23  ? 113 GLN D CD  1 
ATOM   3230 O OE1 . GLN B 2 113 ? 189.659 186.849 194.553 1.00 83.25  ? 113 GLN D OE1 1 
ATOM   3231 N NE2 . GLN B 2 113 ? 188.394 185.181 193.742 1.00 83.77  ? 113 GLN D NE2 1 
ATOM   3232 N N   . GLY B 2 114 ? 185.807 189.727 191.304 1.00 85.39  ? 114 GLY D N   1 
ATOM   3233 C CA  . GLY B 2 114 ? 185.813 190.836 190.375 1.00 86.89  ? 114 GLY D CA  1 
ATOM   3234 C C   . GLY B 2 114 ? 187.183 191.478 190.253 1.00 90.43  ? 114 GLY D C   1 
ATOM   3235 O O   . GLY B 2 114 ? 188.103 191.226 191.031 1.00 90.80  ? 114 GLY D O   1 
ATOM   3236 N N   . THR B 2 115 ? 187.315 192.337 189.243 1.00 97.42  ? 115 THR D N   1 
ATOM   3237 C CA  . THR B 2 115 ? 188.586 192.996 188.969 1.00 95.89  ? 115 THR D CA  1 
ATOM   3238 C C   . THR B 2 115 ? 188.346 194.460 188.631 1.00 95.16  ? 115 THR D C   1 
ATOM   3239 O O   . THR B 2 115 ? 187.279 194.831 188.140 1.00 96.01  ? 115 THR D O   1 
ATOM   3240 C CB  . THR B 2 115 ? 189.349 192.300 187.829 1.00 97.84  ? 115 THR D CB  1 
ATOM   3241 O OG1 . THR B 2 115 ? 190.683 192.819 187.755 1.00 96.50  ? 115 THR D OG1 1 
ATOM   3242 C CG2 . THR B 2 115 ? 188.647 192.506 186.497 1.00 99.05  ? 115 THR D CG2 1 
ATOM   3243 N N   . THR B 2 116 ? 189.354 195.289 188.888 1.00 93.84  ? 116 THR D N   1 
ATOM   3244 C CA  . THR B 2 116 ? 189.233 196.736 188.766 1.00 96.36  ? 116 THR D CA  1 
ATOM   3245 C C   . THR B 2 116 ? 189.813 197.221 187.443 1.00 97.88  ? 116 THR D C   1 
ATOM   3246 O O   . THR B 2 116 ? 190.867 196.751 187.004 1.00 95.84  ? 116 THR D O   1 
ATOM   3247 C CB  . THR B 2 116 ? 189.946 197.440 189.921 1.00 94.97  ? 116 THR D CB  1 
ATOM   3248 O OG1 . THR B 2 116 ? 191.354 197.482 189.658 1.00 95.93  ? 116 THR D OG1 1 
ATOM   3249 C CG2 . THR B 2 116 ? 189.706 196.698 191.226 1.00 96.42  ? 116 THR D CG2 1 
ATOM   3250 N N   . LEU B 2 117 ? 189.121 198.173 186.813 1.00 97.10  ? 117 LEU D N   1 
ATOM   3251 C CA  . LEU B 2 117 ? 189.577 198.805 185.583 1.00 95.37  ? 117 LEU D CA  1 
ATOM   3252 C C   . LEU B 2 117 ? 189.458 200.312 185.741 1.00 94.29  ? 117 LEU D C   1 
ATOM   3253 O O   . LEU B 2 117 ? 188.374 200.825 186.046 1.00 92.50  ? 117 LEU D O   1 
ATOM   3254 C CB  . LEU B 2 117 ? 188.760 198.329 184.378 1.00 93.78  ? 117 LEU D CB  1 
ATOM   3255 C CG  . LEU B 2 117 ? 189.456 198.345 183.016 1.00 92.73  ? 117 LEU D CG  1 
ATOM   3256 C CD1 . LEU B 2 117 ? 190.829 197.714 183.111 1.00 91.41  ? 117 LEU D CD1 1 
ATOM   3257 C CD2 . LEU B 2 117 ? 188.612 197.639 181.969 1.00 93.05  ? 117 LEU D CD2 1 
ATOM   3258 N N   . THR B 2 118 ? 190.571 201.016 185.537 1.00 91.34  ? 118 THR D N   1 
ATOM   3259 C CA  . THR B 2 118 ? 190.629 202.465 185.651 1.00 91.08  ? 118 THR D CA  1 
ATOM   3260 C C   . THR B 2 118 ? 191.221 203.052 184.379 1.00 90.87  ? 118 THR D C   1 
ATOM   3261 O O   . THR B 2 118 ? 192.125 202.470 183.772 1.00 91.84  ? 118 THR D O   1 
ATOM   3262 C CB  . THR B 2 118 ? 191.469 202.910 186.860 1.00 90.64  ? 118 THR D CB  1 
ATOM   3263 O OG1 . THR B 2 118 ? 192.861 202.822 186.534 1.00 89.10  ? 118 THR D OG1 1 
ATOM   3264 C CG2 . THR B 2 118 ? 191.180 202.039 188.074 1.00 91.24  ? 118 THR D CG2 1 
ATOM   3265 N N   . VAL B 2 119 ? 190.706 204.216 183.983 1.00 90.68  ? 119 VAL D N   1 
ATOM   3266 C CA  . VAL B 2 119 ? 191.189 204.908 182.793 1.00 87.46  ? 119 VAL D CA  1 
ATOM   3267 C C   . VAL B 2 119 ? 191.879 206.195 183.220 1.00 89.40  ? 119 VAL D C   1 
ATOM   3268 O O   . VAL B 2 119 ? 191.952 206.507 184.414 1.00 96.23  ? 119 VAL D O   1 
ATOM   3269 C CB  . VAL B 2 119 ? 190.049 205.212 181.806 1.00 86.31  ? 119 VAL D CB  1 
ATOM   3270 C CG1 . VAL B 2 119 ? 189.293 203.944 181.448 1.00 87.11  ? 119 VAL D CG1 1 
ATOM   3271 C CG2 . VAL B 2 119 ? 189.131 206.279 182.366 1.00 87.95  ? 119 VAL D CG2 1 
ATOM   3272 N N   . SER B 2 120 ? 192.386 206.949 182.252 1.00 89.01  ? 120 SER D N   1 
ATOM   3273 C CA  . SER B 2 120 ? 193.035 208.221 182.541 1.00 92.97  ? 120 SER D CA  1 
ATOM   3274 C C   . SER B 2 120 ? 192.554 209.311 181.590 1.00 92.17  ? 120 SER D C   1 
ATOM   3275 O O   . SER B 2 120 ? 192.888 210.484 181.758 1.00 93.09  ? 120 SER D O   1 
ATOM   3276 C CB  . SER B 2 120 ? 194.555 208.079 182.454 1.00 92.98  ? 120 SER D CB  1 
ATOM   3277 O OG  . SER B 2 120 ? 195.166 209.325 182.169 1.00 95.31  ? 120 SER D OG  1 
ATOM   3278 N N   . SER B 2 136 ? 161.073 202.254 177.997 1.00 124.63 ? 124 SER D N   1 
ATOM   3279 C CA  . SER B 2 136 ? 162.252 202.688 178.738 1.00 125.41 ? 124 SER D CA  1 
ATOM   3280 C C   . SER B 2 136 ? 162.802 201.556 179.601 1.00 126.86 ? 124 SER D C   1 
ATOM   3281 O O   . SER B 2 136 ? 163.090 200.468 179.104 1.00 124.34 ? 124 SER D O   1 
ATOM   3282 C CB  . SER B 2 136 ? 161.924 203.901 179.611 1.00 50.00  ? 124 SER D CB  1 
ATOM   3283 O OG  . SER B 2 136 ? 160.972 203.571 180.606 1.00 50.00  ? 124 SER D OG  1 
ATOM   3284 N N   . ASP B 2 137 ? 162.945 201.820 180.898 1.00 118.39 ? 125 ASP D N   1 
ATOM   3285 C CA  . ASP B 2 137 ? 163.450 200.828 181.835 1.00 114.32 ? 125 ASP D CA  1 
ATOM   3286 C C   . ASP B 2 137 ? 162.836 201.077 183.204 1.00 113.20 ? 125 ASP D C   1 
ATOM   3287 O O   . ASP B 2 137 ? 162.602 202.226 183.587 1.00 113.20 ? 125 ASP D O   1 
ATOM   3288 C CB  . ASP B 2 137 ? 164.981 200.860 181.915 1.00 115.28 ? 125 ASP D CB  1 
ATOM   3289 C CG  . ASP B 2 137 ? 165.540 202.271 181.915 1.00 119.75 ? 125 ASP D CG  1 
ATOM   3290 N N   . ILE B 2 138 ? 162.569 199.991 183.931 1.00 95.90  ? 126 ILE D N   1 
ATOM   3291 C CA  . ILE B 2 138 ? 161.957 200.104 185.249 1.00 92.66  ? 126 ILE D CA  1 
ATOM   3292 C C   . ILE B 2 138 ? 162.966 200.673 186.235 1.00 92.64  ? 126 ILE D C   1 
ATOM   3293 O O   . ILE B 2 138 ? 164.125 200.238 186.293 1.00 94.12  ? 126 ILE D O   1 
ATOM   3294 C CB  . ILE B 2 138 ? 161.421 198.737 185.710 1.00 90.19  ? 126 ILE D CB  1 
ATOM   3295 C CG1 . ILE B 2 138 ? 161.046 198.777 187.191 1.00 92.40  ? 126 ILE D CG1 1 
ATOM   3296 C CG2 . ILE B 2 138 ? 162.437 197.642 185.434 1.00 93.29  ? 126 ILE D CG2 1 
ATOM   3297 C CD1 . ILE B 2 138 ? 159.941 197.819 187.566 1.00 93.94  ? 126 ILE D CD1 1 
ATOM   3298 N N   . VAL B 2 139 ? 162.533 201.660 187.015 1.00 97.14  ? 127 VAL D N   1 
ATOM   3299 C CA  . VAL B 2 139 ? 163.392 202.369 187.954 1.00 98.70  ? 127 VAL D CA  1 
ATOM   3300 C C   . VAL B 2 139 ? 163.077 201.885 189.362 1.00 100.03 ? 127 VAL D C   1 
ATOM   3301 O O   . VAL B 2 139 ? 161.911 201.869 189.774 1.00 99.56  ? 127 VAL D O   1 
ATOM   3302 C CB  . VAL B 2 139 ? 163.210 203.893 187.843 1.00 97.56  ? 127 VAL D CB  1 
ATOM   3303 C CG1 . VAL B 2 139 ? 163.980 204.604 188.943 1.00 97.82  ? 127 VAL D CG1 1 
ATOM   3304 C CG2 . VAL B 2 139 ? 163.656 204.381 186.473 1.00 99.08  ? 127 VAL D CG2 1 
ATOM   3305 N N   . MET B 2 140 ? 164.115 201.493 190.095 1.00 102.97 ? 128 MET D N   1 
ATOM   3306 C CA  . MET B 2 140 ? 163.987 201.035 191.471 1.00 101.90 ? 128 MET D CA  1 
ATOM   3307 C C   . MET B 2 140 ? 164.422 202.146 192.417 1.00 102.12 ? 128 MET D C   1 
ATOM   3308 O O   . MET B 2 140 ? 165.471 202.766 192.213 1.00 103.27 ? 128 MET D O   1 
ATOM   3309 C CB  . MET B 2 140 ? 164.826 199.780 191.712 1.00 103.47 ? 128 MET D CB  1 
ATOM   3310 C CG  . MET B 2 140 ? 164.356 198.561 190.943 1.00 103.94 ? 128 MET D CG  1 
ATOM   3311 S SD  . MET B 2 140 ? 162.597 198.262 191.166 1.00 109.72 ? 128 MET D SD  1 
ATOM   3312 C CE  . MET B 2 140 ? 162.623 196.727 192.084 1.00 103.49 ? 128 MET D CE  1 
ATOM   3313 N N   . THR B 2 141 ? 163.617 202.393 193.446 1.00 98.74  ? 129 THR D N   1 
ATOM   3314 C CA  . THR B 2 141 ? 163.867 203.458 194.408 1.00 98.56  ? 129 THR D CA  1 
ATOM   3315 C C   . THR B 2 141 ? 164.161 202.849 195.772 1.00 97.91  ? 129 THR D C   1 
ATOM   3316 O O   . THR B 2 141 ? 163.362 202.059 196.291 1.00 99.93  ? 129 THR D O   1 
ATOM   3317 C CB  . THR B 2 141 ? 162.674 204.411 194.491 1.00 98.86  ? 129 THR D CB  1 
ATOM   3318 O OG1 . THR B 2 141 ? 162.724 205.337 193.399 1.00 100.48 ? 129 THR D OG1 1 
ATOM   3319 C CG2 . THR B 2 141 ? 162.696 205.187 195.801 1.00 98.77  ? 129 THR D CG2 1 
ATOM   3320 N N   . GLN B 2 142 ? 165.311 203.206 196.336 1.00 93.84  ? 130 GLN D N   1 
ATOM   3321 C CA  . GLN B 2 142 ? 165.655 202.894 197.716 1.00 94.67  ? 130 GLN D CA  1 
ATOM   3322 C C   . GLN B 2 142 ? 165.311 204.098 198.581 1.00 95.99  ? 130 GLN D C   1 
ATOM   3323 O O   . GLN B 2 142 ? 165.785 205.209 198.323 1.00 98.12  ? 130 GLN D O   1 
ATOM   3324 C CB  . GLN B 2 142 ? 167.139 202.550 197.852 1.00 99.81  ? 130 GLN D CB  1 
ATOM   3325 C CG  . GLN B 2 142 ? 167.602 201.374 197.004 1.00 99.60  ? 130 GLN D CG  1 
ATOM   3326 C CD  . GLN B 2 142 ? 167.903 200.141 197.833 1.00 95.27  ? 130 GLN D CD  1 
ATOM   3327 O OE1 . GLN B 2 142 ? 168.996 199.998 198.378 1.00 88.30  ? 130 GLN D OE1 1 
ATOM   3328 N NE2 . GLN B 2 142 ? 166.932 199.242 197.929 1.00 97.10  ? 130 GLN D NE2 1 
ATOM   3329 N N   . ALA B 2 143 ? 164.483 203.876 199.603 1.00 106.07 ? 131 ALA D N   1 
ATOM   3330 C CA  . ALA B 2 143 ? 163.967 204.990 200.392 1.00 109.21 ? 131 ALA D CA  1 
ATOM   3331 C C   . ALA B 2 143 ? 165.070 205.695 201.173 1.00 108.82 ? 131 ALA D C   1 
ATOM   3332 O O   . ALA B 2 143 ? 165.094 206.929 201.243 1.00 109.30 ? 131 ALA D O   1 
ATOM   3333 C CB  . ALA B 2 143 ? 162.874 204.498 201.340 1.00 106.21 ? 131 ALA D CB  1 
ATOM   3334 N N   . THR B 2 144 ? 165.990 204.938 201.762 1.00 106.17 ? 132 THR D N   1 
ATOM   3335 C CA  . THR B 2 144 ? 166.951 205.481 202.708 1.00 105.96 ? 132 THR D CA  1 
ATOM   3336 C C   . THR B 2 144 ? 168.370 205.259 202.195 1.00 105.95 ? 132 THR D C   1 
ATOM   3337 O O   . THR B 2 144 ? 168.617 204.410 201.334 1.00 103.60 ? 132 THR D O   1 
ATOM   3338 C CB  . THR B 2 144 ? 166.766 204.834 204.092 1.00 108.56 ? 132 THR D CB  1 
ATOM   3339 O OG1 . THR B 2 144 ? 165.373 204.832 204.428 1.00 106.90 ? 132 THR D OG1 1 
ATOM   3340 C CG2 . THR B 2 144 ? 167.507 205.613 205.169 1.00 108.35 ? 132 THR D CG2 1 
ATOM   3341 N N   . SER B 2 145 ? 169.306 206.044 202.732 1.00 109.98 ? 133 SER D N   1 
ATOM   3342 C CA  . SER B 2 145 ? 170.717 205.913 202.410 1.00 110.02 ? 133 SER D CA  1 
ATOM   3343 C C   . SER B 2 145 ? 171.587 205.552 203.606 1.00 109.54 ? 133 SER D C   1 
ATOM   3344 O O   . SER B 2 145 ? 172.756 205.204 203.408 1.00 109.08 ? 133 SER D O   1 
ATOM   3345 C CB  . SER B 2 145 ? 171.249 207.213 201.787 1.00 108.61 ? 133 SER D CB  1 
ATOM   3346 O OG  . SER B 2 145 ? 171.899 208.012 202.761 1.00 108.57 ? 133 SER D OG  1 
ATOM   3347 N N   . SER B 2 146 ? 171.060 205.621 204.829 1.00 109.29 ? 134 SER D N   1 
ATOM   3348 C CA  . SER B 2 146 ? 171.837 205.301 206.022 1.00 108.16 ? 134 SER D CA  1 
ATOM   3349 C C   . SER B 2 146 ? 170.931 205.108 207.232 1.00 107.45 ? 134 SER D C   1 
ATOM   3350 O O   . SER B 2 146 ? 170.069 205.949 207.506 1.00 108.16 ? 134 SER D O   1 
ATOM   3351 C CB  . SER B 2 146 ? 172.860 206.403 206.304 1.00 108.30 ? 134 SER D CB  1 
ATOM   3352 O OG  . SER B 2 146 ? 173.990 206.276 205.458 1.00 110.54 ? 134 SER D OG  1 
ATOM   3353 N N   . VAL B 2 147 ? 171.114 204.011 207.961 1.00 107.79 ? 135 VAL D N   1 
ATOM   3354 C CA  . VAL B 2 147 ? 170.334 203.739 209.168 1.00 110.56 ? 135 VAL D CA  1 
ATOM   3355 C C   . VAL B 2 147 ? 171.256 203.228 210.270 1.00 113.52 ? 135 VAL D C   1 
ATOM   3356 O O   . VAL B 2 147 ? 171.664 202.058 210.240 1.00 113.31 ? 135 VAL D O   1 
ATOM   3357 C CB  . VAL B 2 147 ? 169.206 202.729 208.896 1.00 111.01 ? 135 VAL D CB  1 
ATOM   3358 C CG1 . VAL B 2 147 ? 168.497 202.365 210.192 1.00 111.18 ? 135 VAL D CG1 1 
ATOM   3359 C CG2 . VAL B 2 147 ? 168.211 203.282 207.890 1.00 108.37 ? 135 VAL D CG2 1 
ATOM   3360 N N   . PRO B 2 148 ? 171.632 204.063 211.239 1.00 105.30 ? 136 PRO D N   1 
ATOM   3361 C CA  . PRO B 2 148 ? 172.321 203.547 212.425 1.00 102.36 ? 136 PRO D CA  1 
ATOM   3362 C C   . PRO B 2 148 ? 171.461 202.522 213.149 1.00 101.29 ? 136 PRO D C   1 
ATOM   3363 O O   . PRO B 2 148 ? 170.231 202.604 213.154 1.00 97.79  ? 136 PRO D O   1 
ATOM   3364 C CB  . PRO B 2 148 ? 172.528 204.796 213.287 1.00 102.21 ? 136 PRO D CB  1 
ATOM   3365 C CG  . PRO B 2 148 ? 172.490 205.950 212.334 1.00 101.23 ? 136 PRO D CG  1 
ATOM   3366 C CD  . PRO B 2 148 ? 171.935 205.486 211.009 1.00 101.55 ? 136 PRO D CD  1 
ATOM   3367 N N   . VAL B 2 149 ? 172.122 201.543 213.767 1.00 104.85 ? 137 VAL D N   1 
ATOM   3368 C CA  . VAL B 2 149 ? 171.422 200.435 214.408 1.00 106.54 ? 137 VAL D CA  1 
ATOM   3369 C C   . VAL B 2 149 ? 172.290 199.877 215.526 1.00 105.12 ? 137 VAL D C   1 
ATOM   3370 O O   . VAL B 2 149 ? 173.493 200.134 215.589 1.00 103.98 ? 137 VAL D O   1 
ATOM   3371 C CB  . VAL B 2 149 ? 171.060 199.338 213.375 1.00 109.66 ? 137 VAL D CB  1 
ATOM   3372 C CG1 . VAL B 2 149 ? 172.254 198.436 213.120 1.00 104.98 ? 137 VAL D CG1 1 
ATOM   3373 C CG2 . VAL B 2 149 ? 169.861 198.542 213.855 1.00 110.02 ? 137 VAL D CG2 1 
ATOM   3374 N N   . THR B 2 150 ? 171.670 199.107 216.417 1.00 101.58 ? 138 THR D N   1 
ATOM   3375 C CA  . THR B 2 150 ? 172.299 198.443 217.546 1.00 99.38  ? 138 THR D CA  1 
ATOM   3376 C C   . THR B 2 150 ? 171.872 196.984 217.583 1.00 99.80  ? 138 THR D C   1 
ATOM   3377 O O   . THR B 2 150 ? 170.761 196.648 217.158 1.00 98.25  ? 138 THR D O   1 
ATOM   3378 C CB  . THR B 2 150 ? 171.916 199.125 218.868 1.00 99.71  ? 138 THR D CB  1 
ATOM   3379 O OG1 . THR B 2 150 ? 172.305 198.299 219.972 1.00 100.75 ? 138 THR D OG1 1 
ATOM   3380 C CG2 . THR B 2 150 ? 170.415 199.366 218.927 1.00 98.44  ? 138 THR D CG2 1 
ATOM   3381 N N   . PRO B 2 151 ? 172.734 196.093 218.076 1.00 95.29  ? 139 PRO D N   1 
ATOM   3382 C CA  . PRO B 2 151 ? 172.373 194.671 218.131 1.00 93.36  ? 139 PRO D CA  1 
ATOM   3383 C C   . PRO B 2 151 ? 171.152 194.421 219.003 1.00 93.35  ? 139 PRO D C   1 
ATOM   3384 O O   . PRO B 2 151 ? 170.917 195.110 219.998 1.00 95.52  ? 139 PRO D O   1 
ATOM   3385 C CB  . PRO B 2 151 ? 173.622 194.012 218.724 1.00 87.99  ? 139 PRO D CB  1 
ATOM   3386 C CG  . PRO B 2 151 ? 174.732 194.925 218.349 1.00 93.26  ? 139 PRO D CG  1 
ATOM   3387 C CD  . PRO B 2 151 ? 174.156 196.311 218.395 1.00 92.10  ? 139 PRO D CD  1 
ATOM   3388 N N   . GLY B 2 152 ? 170.373 193.417 218.613 1.00 91.67  ? 140 GLY D N   1 
ATOM   3389 C CA  . GLY B 2 152 ? 169.193 193.026 219.353 1.00 92.55  ? 140 GLY D CA  1 
ATOM   3390 C C   . GLY B 2 152 ? 167.898 193.671 218.915 1.00 94.71  ? 140 GLY D C   1 
ATOM   3391 O O   . GLY B 2 152 ? 166.884 193.509 219.604 1.00 95.92  ? 140 GLY D O   1 
ATOM   3392 N N   . GLU B 2 153 ? 167.893 194.392 217.801 1.00 97.85  ? 141 GLU D N   1 
ATOM   3393 C CA  . GLU B 2 153 ? 166.702 195.060 217.298 1.00 97.91  ? 141 GLU D CA  1 
ATOM   3394 C C   . GLU B 2 153 ? 166.245 194.408 215.996 1.00 99.89  ? 141 GLU D C   1 
ATOM   3395 O O   . GLU B 2 153 ? 166.818 193.421 215.527 1.00 103.27 ? 141 GLU D O   1 
ATOM   3396 C CB  . GLU B 2 153 ? 166.967 196.552 217.084 1.00 50.00  ? 141 GLU D CB  1 
ATOM   3397 C CG  . GLU B 2 153 ? 167.260 197.321 218.363 1.00 50.00  ? 141 GLU D CG  1 
ATOM   3398 N N   . SER B 2 154 ? 165.193 194.976 215.412 1.00 94.83  ? 142 SER D N   1 
ATOM   3399 C CA  . SER B 2 154 ? 164.648 194.523 214.141 1.00 95.87  ? 142 SER D CA  1 
ATOM   3400 C C   . SER B 2 154 ? 164.621 195.691 213.168 1.00 94.15  ? 142 SER D C   1 
ATOM   3401 O O   . SER B 2 154 ? 164.253 196.809 213.540 1.00 94.31  ? 142 SER D O   1 
ATOM   3402 C CB  . SER B 2 154 ? 163.240 193.945 214.308 1.00 94.99  ? 142 SER D CB  1 
ATOM   3403 O OG  . SER B 2 154 ? 162.512 194.020 213.095 1.00 94.78  ? 142 SER D OG  1 
ATOM   3404 N N   . VAL B 2 155 ? 165.007 195.430 211.922 1.00 91.88  ? 143 VAL D N   1 
ATOM   3405 C CA  . VAL B 2 155 ? 165.171 196.472 210.915 1.00 91.53  ? 143 VAL D CA  1 
ATOM   3406 C C   . VAL B 2 155 ? 164.363 196.101 209.681 1.00 90.61  ? 143 VAL D C   1 
ATOM   3407 O O   . VAL B 2 155 ? 164.423 194.958 209.214 1.00 94.17  ? 143 VAL D O   1 
ATOM   3408 C CB  . VAL B 2 155 ? 166.653 196.677 210.551 1.00 96.35  ? 143 VAL D CB  1 
ATOM   3409 C CG1 . VAL B 2 155 ? 166.791 197.444 209.244 1.00 96.65  ? 143 VAL D CG1 1 
ATOM   3410 C CG2 . VAL B 2 155 ? 167.363 197.403 211.668 1.00 92.83  ? 143 VAL D CG2 1 
ATOM   3411 N N   . SER B 2 156 ? 163.613 197.066 209.155 1.00 82.21  ? 144 SER D N   1 
ATOM   3412 C CA  . SER B 2 156 ? 162.854 196.904 207.924 1.00 88.52  ? 144 SER D CA  1 
ATOM   3413 C C   . SER B 2 156 ? 163.385 197.879 206.884 1.00 88.21  ? 144 SER D C   1 
ATOM   3414 O O   . SER B 2 156 ? 163.562 199.067 207.175 1.00 88.87  ? 144 SER D O   1 
ATOM   3415 C CB  . SER B 2 156 ? 161.361 197.139 208.162 1.00 91.05  ? 144 SER D CB  1 
ATOM   3416 O OG  . SER B 2 156 ? 160.818 196.145 209.013 1.00 94.45  ? 144 SER D OG  1 
ATOM   3417 N N   . ILE B 2 157 ? 163.640 197.376 205.679 1.00 84.03  ? 145 ILE D N   1 
ATOM   3418 C CA  . ILE B 2 157 ? 164.155 198.176 204.573 1.00 81.64  ? 145 ILE D CA  1 
ATOM   3419 C C   . ILE B 2 157 ? 163.162 198.091 203.423 1.00 78.21  ? 145 ILE D C   1 
ATOM   3420 O O   . ILE B 2 157 ? 162.686 197.000 203.090 1.00 82.16  ? 145 ILE D O   1 
ATOM   3421 C CB  . ILE B 2 157 ? 165.551 197.701 204.129 1.00 80.60  ? 145 ILE D CB  1 
ATOM   3422 C CG1 . ILE B 2 157 ? 166.497 197.636 205.327 1.00 75.33  ? 145 ILE D CG1 1 
ATOM   3423 C CG2 . ILE B 2 157 ? 166.113 198.624 203.063 1.00 83.78  ? 145 ILE D CG2 1 
ATOM   3424 C CD1 . ILE B 2 157 ? 167.936 197.411 204.950 1.00 75.89  ? 145 ILE D CD1 1 
ATOM   3425 N N   . SER B 2 158 ? 162.856 199.235 202.816 1.00 82.00  ? 146 SER D N   1 
ATOM   3426 C CA  . SER B 2 158 ? 161.821 199.332 201.797 1.00 87.59  ? 146 SER D CA  1 
ATOM   3427 C C   . SER B 2 158 ? 162.425 199.639 200.433 1.00 91.24  ? 146 SER D C   1 
ATOM   3428 O O   . SER B 2 158 ? 163.335 200.465 200.314 1.00 95.36  ? 146 SER D O   1 
ATOM   3429 C CB  . SER B 2 158 ? 160.797 200.410 202.162 1.00 90.73  ? 146 SER D CB  1 
ATOM   3430 O OG  . SER B 2 158 ? 161.358 201.704 202.040 1.00 93.72  ? 146 SER D OG  1 
ATOM   3431 N N   . CYS B 2 159 ? 161.906 198.966 199.408 1.00 99.17  ? 147 CYS D N   1 
ATOM   3432 C CA  . CYS B 2 159 ? 162.326 199.140 198.024 1.00 97.81  ? 147 CYS D CA  1 
ATOM   3433 C C   . CYS B 2 159 ? 161.079 199.250 197.155 1.00 98.70  ? 147 CYS D C   1 
ATOM   3434 O O   . CYS B 2 159 ? 160.122 198.483 197.324 1.00 103.60 ? 147 CYS D O   1 
ATOM   3435 C CB  . CYS B 2 159 ? 163.231 197.967 197.571 1.00 101.53 ? 147 CYS D CB  1 
ATOM   3436 S SG  . CYS B 2 159 ? 163.749 197.937 195.825 1.00 111.54 ? 147 CYS D SG  1 
ATOM   3437 N N   . ARG B 2 160 ? 161.080 200.216 196.236 1.00 99.24  ? 148 ARG D N   1 
ATOM   3438 C CA  . ARG B 2 160 ? 159.900 200.546 195.448 1.00 101.11 ? 148 ARG D CA  1 
ATOM   3439 C C   . ARG B 2 160 ? 160.189 200.375 193.963 1.00 101.10 ? 148 ARG D C   1 
ATOM   3440 O O   . ARG B 2 160 ? 161.291 200.679 193.498 1.00 102.12 ? 148 ARG D O   1 
ATOM   3441 C CB  . ARG B 2 160 ? 159.440 201.982 195.733 1.00 104.28 ? 148 ARG D CB  1 
ATOM   3442 C CG  . ARG B 2 160 ? 158.272 202.456 194.880 1.00 104.00 ? 148 ARG D CG  1 
ATOM   3443 C CD  . ARG B 2 160 ? 157.487 203.556 195.574 1.00 104.17 ? 148 ARG D CD  1 
ATOM   3444 N NE  . ARG B 2 160 ? 156.389 203.024 196.372 1.00 104.76 ? 148 ARG D NE  1 
ATOM   3445 C CZ  . ARG B 2 160 ? 156.371 202.997 197.697 1.00 104.20 ? 148 ARG D CZ  1 
ATOM   3446 N NH1 . ARG B 2 160 ? 157.381 203.466 198.412 1.00 104.04 ? 148 ARG D NH1 1 
ATOM   3447 N NH2 . ARG B 2 160 ? 155.313 202.488 198.321 1.00 101.15 ? 148 ARG D NH2 1 
ATOM   3448 N N   . SER B 2 161 ? 159.191 199.893 193.223 1.00 100.99 ? 149 SER D N   1 
ATOM   3449 C CA  . SER B 2 161 ? 159.298 199.688 191.786 1.00 104.37 ? 149 SER D CA  1 
ATOM   3450 C C   . SER B 2 161 ? 158.271 200.545 191.058 1.00 103.37 ? 149 SER D C   1 
ATOM   3451 O O   . SER B 2 161 ? 157.172 200.791 191.565 1.00 103.55 ? 149 SER D O   1 
ATOM   3452 C CB  . SER B 2 161 ? 159.097 198.214 191.415 1.00 105.78 ? 149 SER D CB  1 
ATOM   3453 O OG  . SER B 2 161 ? 157.837 197.742 191.855 1.00 107.17 ? 149 SER D OG  1 
ATOM   3454 N N   . SER B 2 162 ? 158.643 201.000 189.859 1.00 96.40  ? 150 SER D N   1 
ATOM   3455 C CA  . SER B 2 162 ? 157.750 201.856 189.083 1.00 95.61  ? 150 SER D CA  1 
ATOM   3456 C C   . SER B 2 162 ? 156.519 201.094 188.609 1.00 94.64  ? 150 SER D C   1 
ATOM   3457 O O   . SER B 2 162 ? 155.400 201.618 188.664 1.00 99.65  ? 150 SER D O   1 
ATOM   3458 C CB  . SER B 2 162 ? 158.499 202.457 187.895 1.00 95.24  ? 150 SER D CB  1 
ATOM   3459 O OG  . SER B 2 162 ? 159.425 201.532 187.355 1.00 97.88  ? 150 SER D OG  1 
ATOM   3460 N N   . LYS B 2 163 ? 156.699 199.863 188.142 1.00 83.94  ? 151 LYS D N   1 
ATOM   3461 C CA  . LYS B 2 163 ? 155.599 199.035 187.677 1.00 85.07  ? 151 LYS D CA  1 
ATOM   3462 C C   . LYS B 2 163 ? 155.597 197.712 188.430 1.00 87.57  ? 151 LYS D C   1 
ATOM   3463 O O   . LYS B 2 163 ? 156.614 197.286 188.985 1.00 91.79  ? 151 LYS D O   1 
ATOM   3464 C CB  . LYS B 2 163 ? 155.678 198.787 186.164 1.00 88.26  ? 151 LYS D CB  1 
ATOM   3465 C CG  . LYS B 2 163 ? 156.586 197.642 185.750 1.00 91.62  ? 151 LYS D CG  1 
ATOM   3466 C CD  . LYS B 2 163 ? 157.108 197.847 184.336 1.00 90.31  ? 151 LYS D CD  1 
ATOM   3467 C CE  . LYS B 2 163 ? 157.925 196.655 183.861 1.00 88.62  ? 151 LYS D CE  1 
ATOM   3468 N NZ  . LYS B 2 163 ? 159.233 196.543 184.560 1.00 86.03  ? 151 LYS D NZ  1 
ATOM   3469 N N   . SER B 2 164 ? 154.431 197.073 188.454 1.00 87.73  ? 152 SER D N   1 
ATOM   3470 C CA  . SER B 2 164 ? 154.266 195.841 189.212 1.00 90.32  ? 152 SER D CA  1 
ATOM   3471 C C   . SER B 2 164 ? 155.137 194.734 188.635 1.00 94.02  ? 152 SER D C   1 
ATOM   3472 O O   . SER B 2 164 ? 155.131 194.484 187.427 1.00 92.14  ? 152 SER D O   1 
ATOM   3473 C CB  . SER B 2 164 ? 152.800 195.415 189.210 1.00 89.65  ? 152 SER D CB  1 
ATOM   3474 O OG  . SER B 2 164 ? 152.680 194.008 189.312 1.00 91.27  ? 152 SER D OG  1 
ATOM   3475 N N   . LEU B 2 165 ? 155.887 194.069 189.511 1.00 88.51  ? 153 LEU D N   1 
ATOM   3476 C CA  . LEU B 2 165 ? 156.752 192.964 189.126 1.00 78.74  ? 153 LEU D CA  1 
ATOM   3477 C C   . LEU B 2 165 ? 156.082 191.607 189.277 1.00 83.47  ? 153 LEU D C   1 
ATOM   3478 O O   . LEU B 2 165 ? 156.717 190.584 189.001 1.00 85.77  ? 153 LEU D O   1 
ATOM   3479 C CB  . LEU B 2 165 ? 158.040 192.997 189.950 1.00 75.06  ? 153 LEU D CB  1 
ATOM   3480 C CG  . LEU B 2 165 ? 158.931 194.212 189.698 1.00 80.60  ? 153 LEU D CG  1 
ATOM   3481 C CD1 . LEU B 2 165 ? 160.127 194.209 190.631 1.00 81.39  ? 153 LEU D CD1 1 
ATOM   3482 C CD2 . LEU B 2 165 ? 159.381 194.241 188.249 1.00 83.82  ? 153 LEU D CD2 1 
ATOM   3483 N N   . LEU B 2 166 ? 154.822 191.571 189.705 1.00 90.60  ? 154 LEU D N   1 
ATOM   3484 C CA  . LEU B 2 166 ? 154.094 190.317 189.862 1.00 84.79  ? 154 LEU D CA  1 
ATOM   3485 C C   . LEU B 2 166 ? 153.601 189.864 188.495 1.00 85.92  ? 154 LEU D C   1 
ATOM   3486 O O   . LEU B 2 166 ? 152.628 190.409 187.964 1.00 84.91  ? 154 LEU D O   1 
ATOM   3487 C CB  . LEU B 2 166 ? 152.934 190.492 190.838 1.00 80.36  ? 154 LEU D CB  1 
ATOM   3488 C CG  . LEU B 2 166 ? 152.125 189.242 191.184 1.00 78.08  ? 154 LEU D CG  1 
ATOM   3489 C CD1 . LEU B 2 166 ? 151.839 189.198 192.675 1.00 79.47  ? 154 LEU D CD1 1 
ATOM   3490 C CD2 . LEU B 2 166 ? 150.829 189.190 190.394 1.00 82.14  ? 154 LEU D CD2 1 
ATOM   3491 N N   . HIS B 2 167 ? 154.271 188.870 187.923 1.00 87.50  ? 155 HIS D N   1 
ATOM   3492 C CA  . HIS B 2 167 ? 153.883 188.359 186.621 1.00 85.81  ? 155 HIS D CA  1 
ATOM   3493 C C   . HIS B 2 167 ? 152.577 187.574 186.729 1.00 87.39  ? 155 HIS D C   1 
ATOM   3494 O O   . HIS B 2 167 ? 152.112 187.225 187.817 1.00 88.94  ? 155 HIS D O   1 
ATOM   3495 C CB  . HIS B 2 167 ? 154.995 187.488 186.041 1.00 79.25  ? 155 HIS D CB  1 
ATOM   3496 C CG  . HIS B 2 167 ? 154.978 187.402 184.548 1.00 83.15  ? 155 HIS D CG  1 
ATOM   3497 N ND1 . HIS B 2 167 ? 154.252 186.452 183.864 1.00 85.34  ? 155 HIS D ND1 1 
ATOM   3498 C CD2 . HIS B 2 167 ? 155.603 188.148 183.606 1.00 87.18  ? 155 HIS D CD2 1 
ATOM   3499 C CE1 . HIS B 2 167 ? 154.428 186.616 182.566 1.00 87.73  ? 155 HIS D CE1 1 
ATOM   3500 N NE2 . HIS B 2 167 ? 155.243 187.639 182.382 1.00 89.48  ? 155 HIS D NE2 1 
ATOM   3501 N N   . SER B 2 168 ? 151.978 187.297 185.568 1.00 78.69  ? 156 SER D N   1 
ATOM   3502 C CA  . SER B 2 168 ? 150.680 186.633 185.532 1.00 74.76  ? 156 SER D CA  1 
ATOM   3503 C C   . SER B 2 168 ? 150.743 185.189 186.008 1.00 75.82  ? 156 SER D C   1 
ATOM   3504 O O   . SER B 2 168 ? 149.702 184.622 186.358 1.00 80.63  ? 156 SER D O   1 
ATOM   3505 C CB  . SER B 2 168 ? 150.105 186.685 184.118 1.00 75.82  ? 156 SER D CB  1 
ATOM   3506 O OG  . SER B 2 168 ? 150.569 185.593 183.343 1.00 74.64  ? 156 SER D OG  1 
ATOM   3507 N N   . ASN B 2 169 ? 151.927 184.579 186.032 1.00 85.27  ? 157 ASN D N   1 
ATOM   3508 C CA  . ASN B 2 169 ? 152.072 183.196 186.465 1.00 85.96  ? 157 ASN D CA  1 
ATOM   3509 C C   . ASN B 2 169 ? 152.177 183.055 187.978 1.00 87.07  ? 157 ASN D C   1 
ATOM   3510 O O   . ASN B 2 169 ? 152.622 182.006 188.460 1.00 87.16  ? 157 ASN D O   1 
ATOM   3511 C CB  . ASN B 2 169 ? 153.290 182.557 185.794 1.00 85.41  ? 157 ASN D CB  1 
ATOM   3512 C CG  . ASN B 2 169 ? 154.563 183.351 186.014 1.00 89.14  ? 157 ASN D CG  1 
ATOM   3513 O OD1 . ASN B 2 169 ? 154.570 184.353 186.728 1.00 92.85  ? 157 ASN D OD1 1 
ATOM   3514 N ND2 . ASN B 2 169 ? 155.652 182.904 185.398 1.00 87.07  ? 157 ASN D ND2 1 
ATOM   3515 N N   . GLY B 2 170 ? 151.787 184.077 188.736 1.00 82.40  ? 158 GLY D N   1 
ATOM   3516 C CA  . GLY B 2 170 ? 151.854 184.001 190.180 1.00 83.12  ? 158 GLY D CA  1 
ATOM   3517 C C   . GLY B 2 170 ? 153.246 184.086 190.758 1.00 81.51  ? 158 GLY D C   1 
ATOM   3518 O O   . GLY B 2 170 ? 153.431 183.777 191.939 1.00 79.10  ? 158 GLY D O   1 
ATOM   3519 N N   . ASN B 2 171 ? 154.229 184.497 189.966 1.00 80.50  ? 159 ASN D N   1 
ATOM   3520 C CA  . ASN B 2 171 ? 155.622 184.533 190.384 1.00 78.79  ? 159 ASN D CA  1 
ATOM   3521 C C   . ASN B 2 171 ? 156.091 185.977 190.473 1.00 81.91  ? 159 ASN D C   1 
ATOM   3522 O O   . ASN B 2 171 ? 155.809 186.782 189.579 1.00 85.44  ? 159 ASN D O   1 
ATOM   3523 C CB  . ASN B 2 171 ? 156.499 183.749 189.407 1.00 78.25  ? 159 ASN D CB  1 
ATOM   3524 C CG  . ASN B 2 171 ? 157.754 183.214 190.053 1.00 81.81  ? 159 ASN D CG  1 
ATOM   3525 O OD1 . ASN B 2 171 ? 158.209 183.731 191.073 1.00 87.79  ? 159 ASN D OD1 1 
ATOM   3526 N ND2 . ASN B 2 171 ? 158.325 182.171 189.463 1.00 81.78  ? 159 ASN D ND2 1 
ATOM   3527 N N   . THR B 2 172 ? 156.799 186.301 191.549 1.00 82.43  ? 160 THR D N   1 
ATOM   3528 C CA  . THR B 2 172 ? 157.392 187.614 191.742 1.00 80.72  ? 160 THR D CA  1 
ATOM   3529 C C   . THR B 2 172 ? 158.897 187.532 191.523 1.00 84.48  ? 160 THR D C   1 
ATOM   3530 O O   . THR B 2 172 ? 159.515 186.485 191.732 1.00 91.06  ? 160 THR D O   1 
ATOM   3531 C CB  . THR B 2 172 ? 157.089 188.155 193.139 1.00 84.24  ? 160 THR D CB  1 
ATOM   3532 O OG1 . THR B 2 172 ? 157.621 189.479 193.269 1.00 87.21  ? 160 THR D OG1 1 
ATOM   3533 C CG2 . THR B 2 172 ? 157.693 187.251 194.197 1.00 85.44  ? 160 THR D CG2 1 
ATOM   3534 N N   . TYR B 2 173 ? 159.484 188.645 191.082 1.00 76.02  ? 161 TYR D N   1 
ATOM   3535 C CA  . TYR B 2 173 ? 160.874 188.667 190.625 1.00 76.74  ? 161 TYR D CA  1 
ATOM   3536 C C   . TYR B 2 173 ? 161.624 189.809 191.303 1.00 79.25  ? 161 TYR D C   1 
ATOM   3537 O O   . TYR B 2 173 ? 161.704 190.918 190.769 1.00 83.62  ? 161 TYR D O   1 
ATOM   3538 C CB  . TYR B 2 173 ? 160.934 188.784 189.106 1.00 74.50  ? 161 TYR D CB  1 
ATOM   3539 C CG  . TYR B 2 173 ? 160.266 187.642 188.374 1.00 76.19  ? 161 TYR D CG  1 
ATOM   3540 C CD1 . TYR B 2 173 ? 158.886 187.588 188.240 1.00 81.40  ? 161 TYR D CD1 1 
ATOM   3541 C CD2 . TYR B 2 173 ? 161.014 186.618 187.817 1.00 78.16  ? 161 TYR D CD2 1 
ATOM   3542 C CE1 . TYR B 2 173 ? 158.275 186.548 187.576 1.00 84.50  ? 161 TYR D CE1 1 
ATOM   3543 C CE2 . TYR B 2 173 ? 160.410 185.576 187.150 1.00 78.12  ? 161 TYR D CE2 1 
ATOM   3544 C CZ  . TYR B 2 173 ? 159.042 185.545 187.033 1.00 80.90  ? 161 TYR D CZ  1 
ATOM   3545 O OH  . TYR B 2 173 ? 158.436 184.505 186.368 1.00 84.24  ? 161 TYR D OH  1 
ATOM   3546 N N   . LEU B 2 174 ? 162.181 189.531 192.478 1.00 75.18  ? 162 LEU D N   1 
ATOM   3547 C CA  . LEU B 2 174 ? 163.066 190.457 193.168 1.00 70.47  ? 162 LEU D CA  1 
ATOM   3548 C C   . LEU B 2 174 ? 164.129 189.650 193.890 1.00 73.20  ? 162 LEU D C   1 
ATOM   3549 O O   . LEU B 2 174 ? 163.830 188.624 194.506 1.00 82.71  ? 162 LEU D O   1 
ATOM   3550 C CB  . LEU B 2 174 ? 162.309 191.337 194.168 1.00 74.17  ? 162 LEU D CB  1 
ATOM   3551 C CG  . LEU B 2 174 ? 162.878 192.699 194.585 1.00 78.74  ? 162 LEU D CG  1 
ATOM   3552 C CD1 . LEU B 2 174 ? 161.942 193.315 195.575 1.00 78.14  ? 162 LEU D CD1 1 
ATOM   3553 C CD2 . LEU B 2 174 ? 164.270 192.648 195.191 1.00 78.14  ? 162 LEU D CD2 1 
ATOM   3554 N N   . TYR B 2 175 ? 165.369 190.119 193.812 1.00 76.07  ? 163 TYR D N   1 
ATOM   3555 C CA  . TYR B 2 175 ? 166.494 189.457 194.453 1.00 82.49  ? 163 TYR D CA  1 
ATOM   3556 C C   . TYR B 2 175 ? 167.215 190.458 195.344 1.00 85.62  ? 163 TYR D C   1 
ATOM   3557 O O   . TYR B 2 175 ? 167.508 191.580 194.916 1.00 89.31  ? 163 TYR D O   1 
ATOM   3558 C CB  . TYR B 2 175 ? 167.448 188.857 193.410 1.00 84.49  ? 163 TYR D CB  1 
ATOM   3559 C CG  . TYR B 2 175 ? 166.819 187.768 192.562 1.00 82.88  ? 163 TYR D CG  1 
ATOM   3560 C CD1 . TYR B 2 175 ? 165.823 188.064 191.642 1.00 78.29  ? 163 TYR D CD1 1 
ATOM   3561 C CD2 . TYR B 2 175 ? 167.210 186.445 192.692 1.00 83.37  ? 163 TYR D CD2 1 
ATOM   3562 C CE1 . TYR B 2 175 ? 165.241 187.083 190.876 1.00 77.09  ? 163 TYR D CE1 1 
ATOM   3563 C CE2 . TYR B 2 175 ? 166.629 185.452 191.925 1.00 84.43  ? 163 TYR D CE2 1 
ATOM   3564 C CZ  . TYR B 2 175 ? 165.644 185.780 191.019 1.00 83.29  ? 163 TYR D CZ  1 
ATOM   3565 O OH  . TYR B 2 175 ? 165.058 184.804 190.249 1.00 89.98  ? 163 TYR D OH  1 
ATOM   3566 N N   . TRP B 2 176 ? 167.483 190.054 196.584 1.00 75.65  ? 164 TRP D N   1 
ATOM   3567 C CA  . TRP B 2 176 ? 168.182 190.881 197.558 1.00 67.75  ? 164 TRP D CA  1 
ATOM   3568 C C   . TRP B 2 176 ? 169.625 190.414 197.678 1.00 70.32  ? 164 TRP D C   1 
ATOM   3569 O O   . TRP B 2 176 ? 169.881 189.228 197.907 1.00 76.64  ? 164 TRP D O   1 
ATOM   3570 C CB  . TRP B 2 176 ? 167.501 190.811 198.924 1.00 70.15  ? 164 TRP D CB  1 
ATOM   3571 C CG  . TRP B 2 176 ? 166.228 191.588 199.026 1.00 73.34  ? 164 TRP D CG  1 
ATOM   3572 C CD1 . TRP B 2 176 ? 164.968 191.132 198.784 1.00 73.75  ? 164 TRP D CD1 1 
ATOM   3573 C CD2 . TRP B 2 176 ? 166.090 192.956 199.424 1.00 74.30  ? 164 TRP D CD2 1 
ATOM   3574 N NE1 . TRP B 2 176 ? 164.054 192.134 198.996 1.00 72.08  ? 164 TRP D NE1 1 
ATOM   3575 C CE2 . TRP B 2 176 ? 164.719 193.264 199.389 1.00 70.13  ? 164 TRP D CE2 1 
ATOM   3576 C CE3 . TRP B 2 176 ? 166.996 193.951 199.800 1.00 77.96  ? 164 TRP D CE3 1 
ATOM   3577 C CZ2 . TRP B 2 176 ? 164.231 194.524 199.716 1.00 71.57  ? 164 TRP D CZ2 1 
ATOM   3578 C CZ3 . TRP B 2 176 ? 166.508 195.201 200.124 1.00 74.15  ? 164 TRP D CZ3 1 
ATOM   3579 C CH2 . TRP B 2 176 ? 165.139 195.476 200.080 1.00 71.59  ? 164 TRP D CH2 1 
ATOM   3580 N N   . PHE B 2 177 ? 170.560 191.346 197.525 1.00 77.24  ? 165 PHE D N   1 
ATOM   3581 C CA  . PHE B 2 177 ? 171.978 191.059 197.675 1.00 78.52  ? 165 PHE D CA  1 
ATOM   3582 C C   . PHE B 2 177 ? 172.554 191.889 198.813 1.00 81.59  ? 165 PHE D C   1 
ATOM   3583 O O   . PHE B 2 177 ? 172.065 192.981 199.117 1.00 87.84  ? 165 PHE D O   1 
ATOM   3584 C CB  . PHE B 2 177 ? 172.757 191.342 196.383 1.00 74.96  ? 165 PHE D CB  1 
ATOM   3585 C CG  . PHE B 2 177 ? 172.052 190.895 195.137 1.00 76.62  ? 165 PHE D CG  1 
ATOM   3586 C CD1 . PHE B 2 177 ? 171.607 189.593 195.007 1.00 73.84  ? 165 PHE D CD1 1 
ATOM   3587 C CD2 . PHE B 2 177 ? 171.844 191.776 194.091 1.00 82.20  ? 165 PHE D CD2 1 
ATOM   3588 C CE1 . PHE B 2 177 ? 170.960 189.179 193.863 1.00 76.81  ? 165 PHE D CE1 1 
ATOM   3589 C CE2 . PHE B 2 177 ? 171.200 191.367 192.941 1.00 83.32  ? 165 PHE D CE2 1 
ATOM   3590 C CZ  . PHE B 2 177 ? 170.757 190.066 192.828 1.00 81.67  ? 165 PHE D CZ  1 
ATOM   3591 N N   . LEU B 2 178 ? 173.599 191.359 199.442 1.00 61.51  ? 166 LEU D N   1 
ATOM   3592 C CA  . LEU B 2 178 ? 174.252 192.017 200.564 1.00 54.16  ? 166 LEU D CA  1 
ATOM   3593 C C   . LEU B 2 178 ? 175.736 192.138 200.272 1.00 50.92  ? 166 LEU D C   1 
ATOM   3594 O O   . LEU B 2 178 ? 176.384 191.147 199.926 1.00 59.64  ? 166 LEU D O   1 
ATOM   3595 C CB  . LEU B 2 178 ? 174.010 191.245 201.869 1.00 55.17  ? 166 LEU D CB  1 
ATOM   3596 C CG  . LEU B 2 178 ? 174.875 191.496 203.107 1.00 63.96  ? 166 LEU D CG  1 
ATOM   3597 C CD1 . LEU B 2 178 ? 174.072 191.183 204.352 1.00 68.15  ? 166 LEU D CD1 1 
ATOM   3598 C CD2 . LEU B 2 178 ? 176.124 190.635 203.093 1.00 67.81  ? 166 LEU D CD2 1 
ATOM   3599 N N   . GLN B 2 179 ? 176.271 193.345 200.424 1.00 61.21  ? 167 GLN D N   1 
ATOM   3600 C CA  . GLN B 2 179 ? 177.682 193.629 200.188 1.00 64.93  ? 167 GLN D CA  1 
ATOM   3601 C C   . GLN B 2 179 ? 178.304 194.071 201.504 1.00 71.23  ? 167 GLN D C   1 
ATOM   3602 O O   . GLN B 2 179 ? 178.068 195.195 201.960 1.00 73.47  ? 167 GLN D O   1 
ATOM   3603 C CB  . GLN B 2 179 ? 177.858 194.698 199.113 1.00 65.89  ? 167 GLN D CB  1 
ATOM   3604 C CG  . GLN B 2 179 ? 179.304 195.061 198.839 1.00 68.44  ? 167 GLN D CG  1 
ATOM   3605 C CD  . GLN B 2 179 ? 179.508 195.640 197.456 1.00 74.69  ? 167 GLN D CD  1 
ATOM   3606 O OE1 . GLN B 2 179 ? 178.560 196.083 196.810 1.00 75.73  ? 167 GLN D OE1 1 
ATOM   3607 N NE2 . GLN B 2 179 ? 180.753 195.643 196.994 1.00 74.66  ? 167 GLN D NE2 1 
ATOM   3608 N N   . ARG B 2 180 ? 179.071 193.179 202.121 1.00 76.71  ? 168 ARG D N   1 
ATOM   3609 C CA  . ARG B 2 180 ? 179.837 193.504 203.309 1.00 70.47  ? 168 ARG D CA  1 
ATOM   3610 C C   . ARG B 2 180 ? 181.124 194.221 202.917 1.00 74.60  ? 168 ARG D C   1 
ATOM   3611 O O   . ARG B 2 180 ? 181.560 194.144 201.766 1.00 81.33  ? 168 ARG D O   1 
ATOM   3612 C CB  . ARG B 2 180 ? 180.147 192.234 204.094 1.00 63.97  ? 168 ARG D CB  1 
ATOM   3613 C CG  . ARG B 2 180 ? 179.009 191.765 204.985 1.00 66.63  ? 168 ARG D CG  1 
ATOM   3614 C CD  . ARG B 2 180 ? 179.248 190.354 205.494 1.00 70.77  ? 168 ARG D CD  1 
ATOM   3615 N NE  . ARG B 2 180 ? 178.020 189.570 205.525 1.00 74.03  ? 168 ARG D NE  1 
ATOM   3616 C CZ  . ARG B 2 180 ? 177.970 188.265 205.752 1.00 74.44  ? 168 ARG D CZ  1 
ATOM   3617 N NH1 . ARG B 2 180 ? 179.066 187.560 205.981 1.00 76.69  ? 168 ARG D NH1 1 
ATOM   3618 N NH2 . ARG B 2 180 ? 176.791 187.651 205.749 1.00 68.89  ? 168 ARG D NH2 1 
ATOM   3619 N N   . PRO B 2 181 ? 181.740 194.948 203.850 1.00 75.43  ? 169 PRO D N   1 
ATOM   3620 C CA  . PRO B 2 181 ? 182.971 195.678 203.518 1.00 77.66  ? 169 PRO D CA  1 
ATOM   3621 C C   . PRO B 2 181 ? 184.060 194.752 202.995 1.00 81.90  ? 169 PRO D C   1 
ATOM   3622 O O   . PRO B 2 181 ? 184.416 193.759 203.633 1.00 81.04  ? 169 PRO D O   1 
ATOM   3623 C CB  . PRO B 2 181 ? 183.368 196.317 204.852 1.00 76.70  ? 169 PRO D CB  1 
ATOM   3624 C CG  . PRO B 2 181 ? 182.086 196.478 205.576 1.00 78.11  ? 169 PRO D CG  1 
ATOM   3625 C CD  . PRO B 2 181 ? 181.243 195.296 205.192 1.00 76.65  ? 169 PRO D CD  1 
ATOM   3626 N N   . GLY B 2 182 ? 184.588 195.092 201.824 1.00 80.99  ? 170 GLY D N   1 
ATOM   3627 C CA  . GLY B 2 182 ? 185.681 194.334 201.233 1.00 76.27  ? 170 GLY D CA  1 
ATOM   3628 C C   . GLY B 2 182 ? 185.351 192.889 200.933 1.00 77.49  ? 170 GLY D C   1 
ATOM   3629 O O   . GLY B 2 182 ? 186.160 191.999 201.223 1.00 80.21  ? 170 GLY D O   1 
ATOM   3630 N N   . GLN B 2 183 ? 184.181 192.632 200.354 1.00 76.64  ? 171 GLN D N   1 
ATOM   3631 C CA  . GLN B 2 183 ? 183.771 191.264 200.073 1.00 78.02  ? 171 GLN D CA  1 
ATOM   3632 C C   . GLN B 2 183 ? 182.730 191.273 198.962 1.00 78.41  ? 171 GLN D C   1 
ATOM   3633 O O   . GLN B 2 183 ? 181.893 192.176 198.897 1.00 78.67  ? 171 GLN D O   1 
ATOM   3634 C CB  . GLN B 2 183 ? 183.222 190.589 201.339 1.00 76.84  ? 171 GLN D CB  1 
ATOM   3635 C CG  . GLN B 2 183 ? 182.113 189.581 201.105 1.00 79.71  ? 171 GLN D CG  1 
ATOM   3636 C CD  . GLN B 2 183 ? 181.522 189.055 202.396 1.00 81.93  ? 171 GLN D CD  1 
ATOM   3637 O OE1 . GLN B 2 183 ? 181.852 189.530 203.482 1.00 83.33  ? 171 GLN D OE1 1 
ATOM   3638 N NE2 . GLN B 2 183 ? 180.642 188.067 202.284 1.00 79.66  ? 171 GLN D NE2 1 
ATOM   3639 N N   . SER B 2 184 ? 182.796 190.268 198.092 1.00 74.52  ? 172 SER D N   1 
ATOM   3640 C CA  . SER B 2 184 ? 181.830 190.146 197.016 1.00 67.65  ? 172 SER D CA  1 
ATOM   3641 C C   . SER B 2 184 ? 180.447 189.811 197.574 1.00 67.90  ? 172 SER D C   1 
ATOM   3642 O O   . SER B 2 184 ? 180.326 189.089 198.566 1.00 78.02  ? 172 SER D O   1 
ATOM   3643 C CB  . SER B 2 184 ? 182.266 189.067 196.031 1.00 75.75  ? 172 SER D CB  1 
ATOM   3644 O OG  . SER B 2 184 ? 182.687 187.897 196.710 1.00 76.28  ? 172 SER D OG  1 
ATOM   3645 N N   . PRO B 2 185 ? 179.389 190.316 196.948 1.00 54.41  ? 173 PRO D N   1 
ATOM   3646 C CA  . PRO B 2 185 ? 178.044 190.125 197.499 1.00 66.95  ? 173 PRO D CA  1 
ATOM   3647 C C   . PRO B 2 185 ? 177.583 188.677 197.427 1.00 68.70  ? 173 PRO D C   1 
ATOM   3648 O O   . PRO B 2 185 ? 178.119 187.852 196.684 1.00 70.49  ? 173 PRO D O   1 
ATOM   3649 C CB  . PRO B 2 185 ? 177.162 191.027 196.627 1.00 69.05  ? 173 PRO D CB  1 
ATOM   3650 C CG  . PRO B 2 185 ? 177.981 191.370 195.442 1.00 67.59  ? 173 PRO D CG  1 
ATOM   3651 C CD  . PRO B 2 185 ? 179.409 191.280 195.840 1.00 60.10  ? 173 PRO D CD  1 
ATOM   3652 N N   . GLN B 2 186 ? 176.563 188.380 198.230 1.00 66.48  ? 174 GLN D N   1 
ATOM   3653 C CA  . GLN B 2 186 ? 175.983 187.049 198.314 1.00 58.04  ? 174 GLN D CA  1 
ATOM   3654 C C   . GLN B 2 186 ? 174.465 187.166 198.319 1.00 61.95  ? 174 GLN D C   1 
ATOM   3655 O O   . GLN B 2 186 ? 173.905 188.211 198.659 1.00 71.98  ? 174 GLN D O   1 
ATOM   3656 C CB  . GLN B 2 186 ? 176.477 186.304 199.561 1.00 62.48  ? 174 GLN D CB  1 
ATOM   3657 C CG  . GLN B 2 186 ? 175.489 186.278 200.715 1.00 67.53  ? 174 GLN D CG  1 
ATOM   3658 C CD  . GLN B 2 186 ? 176.133 185.864 202.024 1.00 74.07  ? 174 GLN D CD  1 
ATOM   3659 O OE1 . GLN B 2 186 ? 177.357 185.860 202.152 1.00 72.71  ? 174 GLN D OE1 1 
ATOM   3660 N NE2 . GLN B 2 186 ? 175.309 185.513 203.004 1.00 74.52  ? 174 GLN D NE2 1 
ATOM   3661 N N   . LEU B 2 187 ? 173.801 186.080 197.933 1.00 53.86  ? 175 LEU D N   1 
ATOM   3662 C CA  . LEU B 2 187 ? 172.348 186.070 197.843 1.00 57.60  ? 175 LEU D CA  1 
ATOM   3663 C C   . LEU B 2 187 ? 171.741 185.931 199.233 1.00 64.82  ? 175 LEU D C   1 
ATOM   3664 O O   . LEU B 2 187 ? 172.208 185.128 200.047 1.00 70.13  ? 175 LEU D O   1 
ATOM   3665 C CB  . LEU B 2 187 ? 171.875 184.930 196.942 1.00 58.57  ? 175 LEU D CB  1 
ATOM   3666 C CG  . LEU B 2 187 ? 170.513 185.040 196.247 1.00 64.48  ? 175 LEU D CG  1 
ATOM   3667 C CD1 . LEU B 2 187 ? 170.432 184.029 195.124 1.00 66.79  ? 175 LEU D CD1 1 
ATOM   3668 C CD2 . LEU B 2 187 ? 169.344 184.851 197.199 1.00 67.21  ? 175 LEU D CD2 1 
ATOM   3669 N N   . LEU B 2 188 ? 170.697 186.715 199.502 1.00 70.10  ? 176 LEU D N   1 
ATOM   3670 C CA  . LEU B 2 188 ? 169.972 186.652 200.764 1.00 67.08  ? 176 LEU D CA  1 
ATOM   3671 C C   . LEU B 2 188 ? 168.546 186.151 200.572 1.00 68.83  ? 176 LEU D C   1 
ATOM   3672 O O   . LEU B 2 188 ? 168.135 185.186 201.222 1.00 74.38  ? 176 LEU D O   1 
ATOM   3673 C CB  . LEU B 2 188 ? 169.966 188.029 201.439 1.00 62.08  ? 176 LEU D CB  1 
ATOM   3674 C CG  . LEU B 2 188 ? 171.237 188.425 202.190 1.00 66.04  ? 176 LEU D CG  1 
ATOM   3675 C CD1 . LEU B 2 188 ? 170.970 189.605 203.103 1.00 70.66  ? 176 LEU D CD1 1 
ATOM   3676 C CD2 . LEU B 2 188 ? 171.792 187.248 202.975 1.00 68.91  ? 176 LEU D CD2 1 
ATOM   3677 N N   . ILE B 2 189 ? 167.778 186.786 199.693 1.00 68.74  ? 177 ILE D N   1 
ATOM   3678 C CA  . ILE B 2 189 ? 166.407 186.383 199.401 1.00 67.15  ? 177 ILE D CA  1 
ATOM   3679 C C   . ILE B 2 189 ? 166.214 186.414 197.893 1.00 74.10  ? 177 ILE D C   1 
ATOM   3680 O O   . ILE B 2 189 ? 166.508 187.424 197.246 1.00 78.97  ? 177 ILE D O   1 
ATOM   3681 C CB  . ILE B 2 189 ? 165.381 187.301 200.094 1.00 71.78  ? 177 ILE D CB  1 
ATOM   3682 C CG1 . ILE B 2 189 ? 165.297 186.987 201.587 1.00 76.87  ? 177 ILE D CG1 1 
ATOM   3683 C CG2 . ILE B 2 189 ? 164.017 187.156 199.451 1.00 72.66  ? 177 ILE D CG2 1 
ATOM   3684 C CD1 . ILE B 2 189 ? 164.839 185.581 201.891 1.00 77.46  ? 177 ILE D CD1 1 
ATOM   3685 N N   . TYR B 2 190 ? 165.720 185.317 197.328 1.00 76.44  ? 178 TYR D N   1 
ATOM   3686 C CA  . TYR B 2 190 ? 165.429 185.244 195.903 1.00 73.14  ? 178 TYR D CA  1 
ATOM   3687 C C   . TYR B 2 190 ? 163.934 185.041 195.704 1.00 71.88  ? 178 TYR D C   1 
ATOM   3688 O O   . TYR B 2 190 ? 163.313 184.239 196.409 1.00 74.47  ? 178 TYR D O   1 
ATOM   3689 C CB  . TYR B 2 190 ? 166.237 184.136 195.219 1.00 74.50  ? 178 TYR D CB  1 
ATOM   3690 C CG  . TYR B 2 190 ? 165.921 182.720 195.647 1.00 76.50  ? 178 TYR D CG  1 
ATOM   3691 C CD1 . TYR B 2 190 ? 166.573 182.138 196.723 1.00 72.98  ? 178 TYR D CD1 1 
ATOM   3692 C CD2 . TYR B 2 190 ? 165.000 181.954 194.947 1.00 77.43  ? 178 TYR D CD2 1 
ATOM   3693 C CE1 . TYR B 2 190 ? 166.297 180.840 197.106 1.00 73.07  ? 178 TYR D CE1 1 
ATOM   3694 C CE2 . TYR B 2 190 ? 164.719 180.656 195.323 1.00 73.59  ? 178 TYR D CE2 1 
ATOM   3695 C CZ  . TYR B 2 190 ? 165.371 180.104 196.402 1.00 72.00  ? 178 TYR D CZ  1 
ATOM   3696 O OH  . TYR B 2 190 ? 165.090 178.812 196.779 1.00 70.85  ? 178 TYR D OH  1 
ATOM   3697 N N   . ARG B 2 191 ? 163.364 185.792 194.759 1.00 71.44  ? 179 ARG D N   1 
ATOM   3698 C CA  . ARG B 2 191 ? 161.928 185.791 194.474 1.00 70.98  ? 179 ARG D CA  1 
ATOM   3699 C C   . ARG B 2 191 ? 161.113 186.302 195.660 1.00 73.79  ? 179 ARG D C   1 
ATOM   3700 O O   . ARG B 2 191 ? 159.976 185.875 195.876 1.00 72.01  ? 179 ARG D O   1 
ATOM   3701 C CB  . ARG B 2 191 ? 161.449 184.406 194.034 1.00 72.55  ? 179 ARG D CB  1 
ATOM   3702 C CG  . ARG B 2 191 ? 161.849 184.061 192.611 1.00 70.38  ? 179 ARG D CG  1 
ATOM   3703 C CD  . ARG B 2 191 ? 161.106 182.849 192.094 1.00 72.60  ? 179 ARG D CD  1 
ATOM   3704 N NE  . ARG B 2 191 ? 161.846 182.181 191.031 1.00 70.93  ? 179 ARG D NE  1 
ATOM   3705 C CZ  . ARG B 2 191 ? 162.605 181.109 191.206 1.00 74.54  ? 179 ARG D CZ  1 
ATOM   3706 N NH1 . ARG B 2 191 ? 162.740 180.545 192.394 1.00 77.32  ? 179 ARG D NH1 1 
ATOM   3707 N NH2 . ARG B 2 191 ? 163.242 180.588 190.161 1.00 77.48  ? 179 ARG D NH2 1 
ATOM   3708 N N   . MET B 2 192 ? 161.719 187.185 196.456 1.00 89.29  ? 180 MET D N   1 
ATOM   3709 C CA  . MET B 2 192 ? 161.047 188.016 197.453 1.00 86.24  ? 180 MET D CA  1 
ATOM   3710 C C   . MET B 2 192 ? 160.582 187.226 198.676 1.00 92.34  ? 180 MET D C   1 
ATOM   3711 O O   . MET B 2 192 ? 160.272 187.813 199.719 1.00 95.21  ? 180 MET D O   1 
ATOM   3712 C CB  . MET B 2 192 ? 159.881 188.767 196.788 1.00 83.50  ? 180 MET D CB  1 
ATOM   3713 C CG  . MET B 2 192 ? 158.638 188.980 197.638 1.00 91.14  ? 180 MET D CG  1 
ATOM   3714 S SD  . MET B 2 192 ? 157.211 189.574 196.715 1.00 106.70 ? 180 MET D SD  1 
ATOM   3715 C CE  . MET B 2 192 ? 156.148 190.096 198.054 1.00 92.71  ? 180 MET D CE  1 
ATOM   3716 N N   . SER B 2 193 ? 160.620 185.896 198.606 1.00 89.45  ? 181 SER D N   1 
ATOM   3717 C CA  . SER B 2 193 ? 160.141 185.095 199.726 1.00 83.86  ? 181 SER D CA  1 
ATOM   3718 C C   . SER B 2 193 ? 161.020 183.908 200.085 1.00 85.81  ? 181 SER D C   1 
ATOM   3719 O O   . SER B 2 193 ? 160.818 183.335 201.160 1.00 91.00  ? 181 SER D O   1 
ATOM   3720 C CB  . SER B 2 193 ? 158.721 184.585 199.444 1.00 84.43  ? 181 SER D CB  1 
ATOM   3721 O OG  . SER B 2 193 ? 157.808 185.662 199.330 1.00 89.65  ? 181 SER D OG  1 
ATOM   3722 N N   . ASN B 2 194 ? 161.975 183.516 199.250 1.00 74.51  ? 182 ASN D N   1 
ATOM   3723 C CA  . ASN B 2 194 ? 162.707 182.272 199.437 1.00 71.67  ? 182 ASN D CA  1 
ATOM   3724 C C   . ASN B 2 194 ? 164.091 182.550 200.004 1.00 74.10  ? 182 ASN D C   1 
ATOM   3725 O O   . ASN B 2 194 ? 164.840 183.367 199.459 1.00 76.90  ? 182 ASN D O   1 
ATOM   3726 C CB  . ASN B 2 194 ? 162.819 181.513 198.116 1.00 74.53  ? 182 ASN D CB  1 
ATOM   3727 C CG  . ASN B 2 194 ? 161.469 181.235 197.490 1.00 80.64  ? 182 ASN D CG  1 
ATOM   3728 O OD1 . ASN B 2 194 ? 160.463 181.836 197.864 1.00 82.75  ? 182 ASN D OD1 1 
ATOM   3729 N ND2 . ASN B 2 194 ? 161.440 180.322 196.528 1.00 82.21  ? 182 ASN D ND2 1 
ATOM   3730 N N   . LEU B 2 195 ? 164.423 181.866 201.094 1.00 71.36  ? 183 LEU D N   1 
ATOM   3731 C CA  . LEU B 2 195 ? 165.733 181.998 201.714 1.00 67.71  ? 183 LEU D CA  1 
ATOM   3732 C C   . LEU B 2 195 ? 166.776 181.221 200.924 1.00 73.02  ? 183 LEU D C   1 
ATOM   3733 O O   . LEU B 2 195 ? 166.524 180.103 200.466 1.00 80.22  ? 183 LEU D O   1 
ATOM   3734 C CB  . LEU B 2 195 ? 165.689 181.497 203.156 1.00 67.39  ? 183 LEU D CB  1 
ATOM   3735 C CG  . LEU B 2 195 ? 165.626 182.559 204.252 1.00 73.03  ? 183 LEU D CG  1 
ATOM   3736 C CD1 . LEU B 2 195 ? 165.992 181.953 205.595 1.00 75.46  ? 183 LEU D CD1 1 
ATOM   3737 C CD2 . LEU B 2 195 ? 166.541 183.721 203.919 1.00 76.47  ? 183 LEU D CD2 1 
ATOM   3738 N N   . ALA B 2 196 ? 167.953 181.818 200.766 1.00 75.64  ? 184 ALA D N   1 
ATOM   3739 C CA  . ALA B 2 196 ? 169.030 181.187 200.023 1.00 79.23  ? 184 ALA D CA  1 
ATOM   3740 C C   . ALA B 2 196 ? 169.686 180.094 200.862 1.00 81.78  ? 184 ALA D C   1 
ATOM   3741 O O   . ALA B 2 196 ? 169.306 179.832 202.006 1.00 83.62  ? 184 ALA D O   1 
ATOM   3742 C CB  . ALA B 2 196 ? 170.055 182.229 199.585 1.00 79.31  ? 184 ALA D CB  1 
ATOM   3743 N N   . SER B 2 197 ? 170.691 179.445 200.282 1.00 88.65  ? 185 SER D N   1 
ATOM   3744 C CA  . SER B 2 197 ? 171.428 178.391 200.962 1.00 89.26  ? 185 SER D CA  1 
ATOM   3745 C C   . SER B 2 197 ? 172.595 178.980 201.742 1.00 90.23  ? 185 SER D C   1 
ATOM   3746 O O   . SER B 2 197 ? 173.236 179.936 201.297 1.00 92.76  ? 185 SER D O   1 
ATOM   3747 C CB  . SER B 2 197 ? 171.938 177.356 199.959 1.00 91.93  ? 185 SER D CB  1 
ATOM   3748 O OG  . SER B 2 197 ? 173.292 177.601 199.620 1.00 91.80  ? 185 SER D OG  1 
ATOM   3749 N N   . GLY B 2 198 ? 172.865 178.403 202.910 1.00 76.04  ? 186 GLY D N   1 
ATOM   3750 C CA  . GLY B 2 198 ? 173.958 178.877 203.733 1.00 77.15  ? 186 GLY D CA  1 
ATOM   3751 C C   . GLY B 2 198 ? 173.717 180.209 204.401 1.00 79.29  ? 186 GLY D C   1 
ATOM   3752 O O   . GLY B 2 198 ? 174.677 180.910 204.728 1.00 79.94  ? 186 GLY D O   1 
ATOM   3753 N N   . VAL B 2 199 ? 172.459 180.580 204.615 1.00 82.06  ? 187 VAL D N   1 
ATOM   3754 C CA  . VAL B 2 199 ? 172.119 181.867 205.213 1.00 80.60  ? 187 VAL D CA  1 
ATOM   3755 C C   . VAL B 2 199 ? 171.187 181.622 206.395 1.00 84.12  ? 187 VAL D C   1 
ATOM   3756 O O   . VAL B 2 199 ? 170.269 180.796 206.294 1.00 88.81  ? 187 VAL D O   1 
ATOM   3757 C CB  . VAL B 2 199 ? 171.491 182.805 204.170 1.00 81.69  ? 187 VAL D CB  1 
ATOM   3758 C CG1 . VAL B 2 199 ? 170.549 183.792 204.824 1.00 81.39  ? 187 VAL D CG1 1 
ATOM   3759 C CG2 . VAL B 2 199 ? 172.578 183.533 203.395 1.00 82.71  ? 187 VAL D CG2 1 
ATOM   3760 N N   . PRO B 2 200 ? 171.386 182.300 207.525 1.00 82.41  ? 188 PRO D N   1 
ATOM   3761 C CA  . PRO B 2 200 ? 170.546 182.053 208.704 1.00 80.93  ? 188 PRO D CA  1 
ATOM   3762 C C   . PRO B 2 200 ? 169.082 182.370 208.439 1.00 85.62  ? 188 PRO D C   1 
ATOM   3763 O O   . PRO B 2 200 ? 168.713 183.014 207.456 1.00 87.24  ? 188 PRO D O   1 
ATOM   3764 C CB  . PRO B 2 200 ? 171.137 182.988 209.763 1.00 83.93  ? 188 PRO D CB  1 
ATOM   3765 C CG  . PRO B 2 200 ? 172.538 183.228 209.315 1.00 84.75  ? 188 PRO D CG  1 
ATOM   3766 C CD  . PRO B 2 200 ? 172.488 183.230 207.819 1.00 83.56  ? 188 PRO D CD  1 
ATOM   3767 N N   . ASP B 2 201 ? 168.237 181.904 209.355 1.00 96.16  ? 189 ASP D N   1 
ATOM   3768 C CA  . ASP B 2 201 ? 166.791 182.038 209.238 1.00 100.40 ? 189 ASP D CA  1 
ATOM   3769 C C   . ASP B 2 201 ? 166.275 183.371 209.763 1.00 99.16  ? 189 ASP D C   1 
ATOM   3770 O O   . ASP B 2 201 ? 165.057 183.564 209.838 1.00 97.83  ? 189 ASP D O   1 
ATOM   3771 C CB  . ASP B 2 201 ? 166.098 180.889 209.975 1.00 99.01  ? 189 ASP D CB  1 
ATOM   3772 C CG  . ASP B 2 201 ? 164.821 180.444 209.291 1.00 101.70 ? 189 ASP D CG  1 
ATOM   3773 O OD1 . ASP B 2 201 ? 164.320 181.186 208.420 1.00 103.45 ? 189 ASP D OD1 1 
ATOM   3774 O OD2 . ASP B 2 201 ? 164.316 179.352 209.626 1.00 100.81 ? 189 ASP D OD2 1 
ATOM   3775 N N   . ARG B 2 202 ? 167.169 184.288 210.135 1.00 92.58  ? 190 ARG D N   1 
ATOM   3776 C CA  . ARG B 2 202 ? 166.733 185.581 210.650 1.00 92.90  ? 190 ARG D CA  1 
ATOM   3777 C C   . ARG B 2 202 ? 166.074 186.422 209.564 1.00 93.07  ? 190 ARG D C   1 
ATOM   3778 O O   . ARG B 2 202 ? 165.094 187.128 209.827 1.00 96.44  ? 190 ARG D O   1 
ATOM   3779 C CB  . ARG B 2 202 ? 167.922 186.327 211.252 1.00 90.77  ? 190 ARG D CB  1 
ATOM   3780 C CG  . ARG B 2 202 ? 168.732 185.502 212.230 1.00 88.81  ? 190 ARG D CG  1 
ATOM   3781 C CD  . ARG B 2 202 ? 169.946 186.270 212.709 1.00 90.26  ? 190 ARG D CD  1 
ATOM   3782 N NE  . ARG B 2 202 ? 170.940 186.411 211.653 1.00 90.33  ? 190 ARG D NE  1 
ATOM   3783 C CZ  . ARG B 2 202 ? 172.034 187.151 211.753 1.00 92.44  ? 190 ARG D CZ  1 
ATOM   3784 N NH1 . ARG B 2 202 ? 172.304 187.839 212.850 1.00 93.16  ? 190 ARG D NH1 1 
ATOM   3785 N NH2 . ARG B 2 202 ? 172.878 187.203 210.727 1.00 94.34  ? 190 ARG D NH2 1 
ATOM   3786 N N   . PHE B 2 203 ? 166.595 186.359 208.343 1.00 79.20  ? 191 PHE D N   1 
ATOM   3787 C CA  . PHE B 2 203 ? 166.122 187.225 207.274 1.00 81.90  ? 191 PHE D CA  1 
ATOM   3788 C C   . PHE B 2 203 ? 164.734 186.809 206.800 1.00 83.92  ? 191 PHE D C   1 
ATOM   3789 O O   . PHE B 2 203 ? 164.362 185.634 206.848 1.00 87.71  ? 191 PHE D O   1 
ATOM   3790 C CB  . PHE B 2 203 ? 167.102 187.194 206.103 1.00 81.24  ? 191 PHE D CB  1 
ATOM   3791 C CG  . PHE B 2 203 ? 168.492 187.624 206.465 1.00 79.84  ? 191 PHE D CG  1 
ATOM   3792 C CD1 . PHE B 2 203 ? 169.583 186.875 206.071 1.00 87.11  ? 191 PHE D CD1 1 
ATOM   3793 C CD2 . PHE B 2 203 ? 168.711 188.776 207.194 1.00 80.06  ? 191 PHE D CD2 1 
ATOM   3794 C CE1 . PHE B 2 203 ? 170.866 187.263 206.400 1.00 89.11  ? 191 PHE D CE1 1 
ATOM   3795 C CE2 . PHE B 2 203 ? 169.991 189.170 207.523 1.00 84.43  ? 191 PHE D CE2 1 
ATOM   3796 C CZ  . PHE B 2 203 ? 171.069 188.412 207.126 1.00 87.39  ? 191 PHE D CZ  1 
ATOM   3797 N N   . SER B 2 204 ? 163.961 187.793 206.341 1.00 81.78  ? 192 SER D N   1 
ATOM   3798 C CA  . SER B 2 204 ? 162.669 187.516 205.730 1.00 80.49  ? 192 SER D CA  1 
ATOM   3799 C C   . SER B 2 204 ? 162.319 188.646 204.774 1.00 84.60  ? 192 SER D C   1 
ATOM   3800 O O   . SER B 2 204 ? 162.868 189.745 204.858 1.00 93.21  ? 192 SER D O   1 
ATOM   3801 C CB  . SER B 2 204 ? 161.569 187.348 206.785 1.00 85.98  ? 192 SER D CB  1 
ATOM   3802 O OG  . SER B 2 204 ? 160.284 187.414 206.193 1.00 88.37  ? 192 SER D OG  1 
ATOM   3803 N N   . GLY B 2 205 ? 161.395 188.368 203.867 1.00 85.34  ? 193 GLY D N   1 
ATOM   3804 C CA  . GLY B 2 205 ? 160.963 189.363 202.902 1.00 88.43  ? 193 GLY D CA  1 
ATOM   3805 C C   . GLY B 2 205 ? 159.473 189.271 202.662 1.00 90.73  ? 193 GLY D C   1 
ATOM   3806 O O   . GLY B 2 205 ? 158.871 188.200 202.765 1.00 91.56  ? 193 GLY D O   1 
ATOM   3807 N N   . SER B 2 206 ? 158.878 190.414 202.334 1.00 94.48  ? 194 SER D N   1 
ATOM   3808 C CA  . SER B 2 206 ? 157.441 190.477 202.100 1.00 92.34  ? 194 SER D CA  1 
ATOM   3809 C C   . SER B 2 206 ? 157.131 191.715 201.268 1.00 91.25  ? 194 SER D C   1 
ATOM   3810 O O   . SER B 2 206 ? 158.025 192.479 200.895 1.00 93.75  ? 194 SER D O   1 
ATOM   3811 C CB  . SER B 2 206 ? 156.667 190.486 203.422 1.00 95.75  ? 194 SER D CB  1 
ATOM   3812 O OG  . SER B 2 206 ? 157.056 191.581 204.232 1.00 95.56  ? 194 SER D OG  1 
ATOM   3813 N N   . GLY B 2 207 ? 155.853 191.902 200.972 1.00 89.90  ? 195 GLY D N   1 
ATOM   3814 C CA  . GLY B 2 207 ? 155.392 193.080 200.277 1.00 92.33  ? 195 GLY D CA  1 
ATOM   3815 C C   . GLY B 2 207 ? 154.299 192.731 199.293 1.00 90.91  ? 195 GLY D C   1 
ATOM   3816 O O   . GLY B 2 207 ? 153.674 191.675 199.379 1.00 89.58  ? 195 GLY D O   1 
ATOM   3817 N N   . SER B 2 208 ? 154.072 193.650 198.360 1.00 90.27  ? 196 SER D N   1 
ATOM   3818 C CA  . SER B 2 208 ? 153.118 193.460 197.280 1.00 86.59  ? 196 SER D CA  1 
ATOM   3819 C C   . SER B 2 208 ? 153.609 194.253 196.077 1.00 90.47  ? 196 SER D C   1 
ATOM   3820 O O   . SER B 2 208 ? 154.714 194.805 196.081 1.00 96.56  ? 196 SER D O   1 
ATOM   3821 C CB  . SER B 2 208 ? 151.710 193.885 197.702 1.00 89.11  ? 196 SER D CB  1 
ATOM   3822 O OG  . SER B 2 208 ? 151.454 195.228 197.333 1.00 91.95  ? 196 SER D OG  1 
ATOM   3823 N N   . GLY B 2 209 ? 152.776 194.311 195.042 1.00 91.47  ? 197 GLY D N   1 
ATOM   3824 C CA  . GLY B 2 209 ? 153.135 195.031 193.837 1.00 90.93  ? 197 GLY D CA  1 
ATOM   3825 C C   . GLY B 2 209 ? 153.563 196.456 194.117 1.00 93.16  ? 197 GLY D C   1 
ATOM   3826 O O   . GLY B 2 209 ? 152.835 197.216 194.764 1.00 97.40  ? 197 GLY D O   1 
ATOM   3827 N N   . THR B 2 210 ? 154.760 196.812 193.652 1.00 89.57  ? 198 THR D N   1 
ATOM   3828 C CA  . THR B 2 210 ? 155.355 198.134 193.814 1.00 93.22  ? 198 THR D CA  1 
ATOM   3829 C C   . THR B 2 210 ? 155.633 198.494 195.270 1.00 93.44  ? 198 THR D C   1 
ATOM   3830 O O   . THR B 2 210 ? 155.634 199.679 195.621 1.00 98.72  ? 198 THR D O   1 
ATOM   3831 C CB  . THR B 2 210 ? 154.442 199.203 193.185 1.00 50.00  ? 198 THR D CB  1 
ATOM   3832 O OG1 . THR B 2 210 ? 154.295 198.944 191.784 1.00 50.00  ? 198 THR D OG1 1 
ATOM   3833 C CG2 . THR B 2 210 ? 155.115 200.567 193.220 1.00 50.00  ? 198 THR D CG2 1 
ATOM   3834 N N   . ALA B 2 211 ? 155.879 197.508 196.131 1.00 85.52  ? 199 ALA D N   1 
ATOM   3835 C CA  . ALA B 2 211 ? 156.272 197.791 197.512 1.00 87.77  ? 199 ALA D CA  1 
ATOM   3836 C C   . ALA B 2 211 ? 156.916 196.545 198.093 1.00 91.44  ? 199 ALA D C   1 
ATOM   3837 O O   . ALA B 2 211 ? 156.285 195.486 198.122 1.00 99.81  ? 199 ALA D O   1 
ATOM   3838 C CB  . ALA B 2 211 ? 155.067 198.216 198.352 1.00 91.38  ? 199 ALA D CB  1 
ATOM   3839 N N   . PHE B 2 212 ? 158.156 196.656 198.565 1.00 84.91  ? 200 PHE D N   1 
ATOM   3840 C CA  . PHE B 2 212 ? 158.866 195.483 199.048 1.00 84.43  ? 200 PHE D CA  1 
ATOM   3841 C C   . PHE B 2 212 ? 159.615 195.809 200.329 1.00 86.28  ? 200 PHE D C   1 
ATOM   3842 O O   . PHE B 2 212 ? 160.195 196.890 200.457 1.00 90.70  ? 200 PHE D O   1 
ATOM   3843 C CB  . PHE B 2 212 ? 159.817 194.979 197.971 1.00 85.35  ? 200 PHE D CB  1 
ATOM   3844 C CG  . PHE B 2 212 ? 159.123 194.583 196.702 1.00 88.38  ? 200 PHE D CG  1 
ATOM   3845 C CD1 . PHE B 2 212 ? 158.287 193.480 196.671 1.00 87.95  ? 200 PHE D CD1 1 
ATOM   3846 C CD2 . PHE B 2 212 ? 159.273 195.334 195.550 1.00 89.43  ? 200 PHE D CD2 1 
ATOM   3847 C CE1 . PHE B 2 212 ? 157.641 193.117 195.507 1.00 89.15  ? 200 PHE D CE1 1 
ATOM   3848 C CE2 . PHE B 2 212 ? 158.631 194.974 194.385 1.00 89.85  ? 200 PHE D CE2 1 
ATOM   3849 C CZ  . PHE B 2 212 ? 157.812 193.866 194.363 1.00 90.75  ? 200 PHE D CZ  1 
ATOM   3850 N N   . THR B 2 213 ? 159.604 194.868 201.274 1.00 91.31  ? 201 THR D N   1 
ATOM   3851 C CA  . THR B 2 213 ? 160.210 195.064 202.583 1.00 94.07  ? 201 THR D CA  1 
ATOM   3852 C C   . THR B 2 213 ? 161.076 193.866 202.941 1.00 93.33  ? 201 THR D C   1 
ATOM   3853 O O   . THR B 2 213 ? 160.625 192.717 202.860 1.00 93.53  ? 201 THR D O   1 
ATOM   3854 C CB  . THR B 2 213 ? 159.140 195.274 203.660 1.00 92.60  ? 201 THR D CB  1 
ATOM   3855 O OG1 . THR B 2 213 ? 158.174 196.225 203.197 1.00 93.10  ? 201 THR D OG1 1 
ATOM   3856 C CG2 . THR B 2 213 ? 159.770 195.785 204.944 1.00 89.95  ? 201 THR D CG2 1 
ATOM   3857 N N   . LEU B 2 214 ? 162.315 194.144 203.336 1.00 87.87  ? 202 LEU D N   1 
ATOM   3858 C CA  . LEU B 2 214 ? 163.229 193.147 203.880 1.00 83.92  ? 202 LEU D CA  1 
ATOM   3859 C C   . LEU B 2 214 ? 163.315 193.359 205.385 1.00 85.05  ? 202 LEU D C   1 
ATOM   3860 O O   . LEU B 2 214 ? 163.604 194.471 205.840 1.00 88.56  ? 202 LEU D O   1 
ATOM   3861 C CB  . LEU B 2 214 ? 164.613 193.261 203.243 1.00 86.06  ? 202 LEU D CB  1 
ATOM   3862 C CG  . LEU B 2 214 ? 165.705 192.324 203.770 1.00 86.69  ? 202 LEU D CG  1 
ATOM   3863 C CD1 . LEU B 2 214 ? 165.407 190.882 203.408 1.00 87.44  ? 202 LEU D CD1 1 
ATOM   3864 C CD2 . LEU B 2 214 ? 167.077 192.733 203.258 1.00 86.10  ? 202 LEU D CD2 1 
ATOM   3865 N N   . THR B 2 215 ? 163.061 192.302 206.151 1.00 89.32  ? 203 THR D N   1 
ATOM   3866 C CA  . THR B 2 215 ? 163.008 192.369 207.603 1.00 88.12  ? 203 THR D CA  1 
ATOM   3867 C C   . THR B 2 215 ? 164.105 191.499 208.197 1.00 85.63  ? 203 THR D C   1 
ATOM   3868 O O   . THR B 2 215 ? 164.232 190.319 207.844 1.00 87.87  ? 203 THR D O   1 
ATOM   3869 C CB  . THR B 2 215 ? 161.643 191.916 208.127 1.00 91.57  ? 203 THR D CB  1 
ATOM   3870 O OG1 . THR B 2 215 ? 161.204 190.768 207.391 1.00 94.21  ? 203 THR D OG1 1 
ATOM   3871 C CG2 . THR B 2 215 ? 160.619 193.028 207.976 1.00 91.90  ? 203 THR D CG2 1 
ATOM   3872 N N   . ILE B 2 216 ? 164.893 192.087 209.092 1.00 84.34  ? 204 ILE D N   1 
ATOM   3873 C CA  . ILE B 2 216 ? 165.921 191.375 209.840 1.00 85.39  ? 204 ILE D CA  1 
ATOM   3874 C C   . ILE B 2 216 ? 165.566 191.443 211.317 1.00 91.38  ? 204 ILE D C   1 
ATOM   3875 O O   . ILE B 2 216 ? 165.314 192.530 211.851 1.00 95.85  ? 204 ILE D O   1 
ATOM   3876 C CB  . ILE B 2 216 ? 167.324 191.956 209.592 1.00 86.28  ? 204 ILE D CB  1 
ATOM   3877 C CG1 . ILE B 2 216 ? 167.496 192.344 208.125 1.00 90.20  ? 204 ILE D CG1 1 
ATOM   3878 C CG2 . ILE B 2 216 ? 168.379 190.948 209.987 1.00 86.34  ? 204 ILE D CG2 1 
ATOM   3879 C CD1 . ILE B 2 216 ? 168.828 192.984 207.822 1.00 87.49  ? 204 ILE D CD1 1 
ATOM   3880 N N   . SER B 2 217 ? 165.549 190.286 211.972 1.00 98.65  ? 205 SER D N   1 
ATOM   3881 C CA  . SER B 2 217 ? 165.237 190.178 213.389 1.00 97.89  ? 205 SER D CA  1 
ATOM   3882 C C   . SER B 2 217 ? 166.439 189.617 214.134 1.00 97.25  ? 205 SER D C   1 
ATOM   3883 O O   . SER B 2 217 ? 167.143 188.741 213.622 1.00 101.54 ? 205 SER D O   1 
ATOM   3884 C CB  . SER B 2 217 ? 164.014 189.286 213.617 1.00 96.99  ? 205 SER D CB  1 
ATOM   3885 O OG  . SER B 2 217 ? 162.924 189.706 212.817 1.00 96.49  ? 205 SER D OG  1 
ATOM   3886 N N   . ARG B 2 218 ? 166.667 190.129 215.346 1.00 87.96  ? 206 ARG D N   1 
ATOM   3887 C CA  . ARG B 2 218 ? 167.775 189.708 216.204 1.00 89.28  ? 206 ARG D CA  1 
ATOM   3888 C C   . ARG B 2 218 ? 169.120 189.924 215.502 1.00 92.00  ? 206 ARG D C   1 
ATOM   3889 O O   . ARG B 2 218 ? 169.842 188.988 215.156 1.00 94.50  ? 206 ARG D O   1 
ATOM   3890 C CB  . ARG B 2 218 ? 167.604 188.250 216.649 1.00 89.60  ? 206 ARG D CB  1 
ATOM   3891 N N   . LEU B 2 219 ? 169.424 191.203 215.293 1.00 88.49  ? 207 LEU D N   1 
ATOM   3892 C CA  . LEU B 2 219 ? 170.663 191.584 214.629 1.00 88.67  ? 207 LEU D CA  1 
ATOM   3893 C C   . LEU B 2 219 ? 171.873 191.087 215.406 1.00 92.22  ? 207 LEU D C   1 
ATOM   3894 O O   . LEU B 2 219 ? 171.869 191.041 216.639 1.00 97.08  ? 207 LEU D O   1 
ATOM   3895 C CB  . LEU B 2 219 ? 170.745 193.102 214.483 1.00 87.91  ? 207 LEU D CB  1 
ATOM   3896 C CG  . LEU B 2 219 ? 170.647 193.665 213.069 1.00 90.76  ? 207 LEU D CG  1 
ATOM   3897 C CD1 . LEU B 2 219 ? 169.342 193.242 212.437 1.00 92.24  ? 207 LEU D CD1 1 
ATOM   3898 C CD2 . LEU B 2 219 ? 170.771 195.166 213.081 1.00 92.04  ? 207 LEU D CD2 1 
ATOM   3899 N N   . GLU B 2 220 ? 172.918 190.711 214.672 1.00 83.55  ? 208 GLU D N   1 
ATOM   3900 C CA  . GLU B 2 220 ? 174.184 190.326 215.279 1.00 83.21  ? 208 GLU D CA  1 
ATOM   3901 C C   . GLU B 2 220 ? 175.336 191.004 214.553 1.00 83.39  ? 208 GLU D C   1 
ATOM   3902 O O   . GLU B 2 220 ? 175.114 191.812 213.646 1.00 80.67  ? 208 GLU D O   1 
ATOM   3903 C CB  . GLU B 2 220 ? 174.357 188.806 215.255 1.00 50.00  ? 208 GLU D CB  1 
ATOM   3904 C CG  . GLU B 2 220 ? 175.625 188.315 215.936 1.00 50.00  ? 208 GLU D CG  1 
ATOM   3905 N N   . ALA B 2 221 ? 176.566 190.688 214.943 1.00 92.09  ? 209 ALA D N   1 
ATOM   3906 C CA  . ALA B 2 221 ? 177.730 191.237 214.267 1.00 90.39  ? 209 ALA D CA  1 
ATOM   3907 C C   . ALA B 2 221 ? 177.847 190.641 212.866 1.00 92.82  ? 209 ALA D C   1 
ATOM   3908 O O   . ALA B 2 221 ? 177.071 189.770 212.460 1.00 94.64  ? 209 ALA D O   1 
ATOM   3909 C CB  . ALA B 2 221 ? 178.992 190.976 215.086 1.00 88.15  ? 209 ALA D CB  1 
ATOM   3910 N N   . GLU B 2 222 ? 178.843 191.120 212.117 1.00 90.07  ? 210 GLU D N   1 
ATOM   3911 C CA  . GLU B 2 222 ? 179.061 190.706 210.731 1.00 89.51  ? 210 GLU D CA  1 
ATOM   3912 C C   . GLU B 2 222 ? 177.816 190.928 209.879 1.00 85.99  ? 210 GLU D C   1 
ATOM   3913 O O   . GLU B 2 222 ? 177.490 190.115 209.012 1.00 84.12  ? 210 GLU D O   1 
ATOM   3914 C CB  . GLU B 2 222 ? 179.480 189.236 210.674 1.00 50.00  ? 210 GLU D CB  1 
ATOM   3915 C CG  . GLU B 2 222 ? 180.846 188.955 211.281 1.00 50.00  ? 210 GLU D CG  1 
ATOM   3916 N N   . ASP B 2 223 ? 177.112 192.036 210.125 1.00 79.07  ? 211 ASP D N   1 
ATOM   3917 C CA  . ASP B 2 223 ? 175.881 192.352 209.411 1.00 75.19  ? 211 ASP D CA  1 
ATOM   3918 C C   . ASP B 2 223 ? 175.831 193.814 208.980 1.00 73.54  ? 211 ASP D C   1 
ATOM   3919 O O   . ASP B 2 223 ? 174.742 194.357 208.779 1.00 72.37  ? 211 ASP D O   1 
ATOM   3920 C CB  . ASP B 2 223 ? 174.659 192.014 210.266 1.00 72.01  ? 211 ASP D CB  1 
ATOM   3921 C CG  . ASP B 2 223 ? 173.535 191.412 209.456 1.00 78.44  ? 211 ASP D CG  1 
ATOM   3922 O OD1 . ASP B 2 223 ? 173.197 191.979 208.397 1.00 80.39  ? 211 ASP D OD1 1 
ATOM   3923 O OD2 . ASP B 2 223 ? 172.990 190.371 209.875 1.00 80.38  ? 211 ASP D OD2 1 
ATOM   3924 N N   . VAL B 2 224 ? 176.982 194.458 208.838 1.00 75.50  ? 212 VAL D N   1 
ATOM   3925 C CA  . VAL B 2 224 ? 177.058 195.830 208.354 1.00 77.66  ? 212 VAL D CA  1 
ATOM   3926 C C   . VAL B 2 224 ? 177.516 195.810 206.904 1.00 80.78  ? 212 VAL D C   1 
ATOM   3927 O O   . VAL B 2 224 ? 178.275 194.932 206.478 1.00 83.03  ? 212 VAL D O   1 
ATOM   3928 C CB  . VAL B 2 224 ? 177.993 196.689 209.231 1.00 80.69  ? 212 VAL D CB  1 
ATOM   3929 C CG1 . VAL B 2 224 ? 177.604 196.563 210.693 1.00 77.50  ? 212 VAL D CG1 1 
ATOM   3930 C CG2 . VAL B 2 224 ? 179.444 196.284 209.032 1.00 81.62  ? 212 VAL D CG2 1 
ATOM   3931 N N   . GLY B 2 225 ? 177.035 196.768 206.136 1.00 80.86  ? 213 GLY D N   1 
ATOM   3932 C CA  . GLY B 2 225 ? 177.338 196.843 204.721 1.00 81.27  ? 213 GLY D CA  1 
ATOM   3933 C C   . GLY B 2 225 ? 176.207 197.534 203.978 1.00 82.35  ? 213 GLY D C   1 
ATOM   3934 O O   . GLY B 2 225 ? 175.513 198.382 204.536 1.00 89.59  ? 213 GLY D O   1 
ATOM   3935 N N   . VAL B 2 226 ? 176.041 197.151 202.714 1.00 69.11  ? 214 VAL D N   1 
ATOM   3936 C CA  . VAL B 2 226 ? 175.009 197.721 201.857 1.00 63.49  ? 214 VAL D CA  1 
ATOM   3937 C C   . VAL B 2 226 ? 174.081 196.605 201.395 1.00 70.01  ? 214 VAL D C   1 
ATOM   3938 O O   . VAL B 2 226 ? 174.487 195.447 201.264 1.00 82.91  ? 214 VAL D O   1 
ATOM   3939 C CB  . VAL B 2 226 ? 175.616 198.465 200.648 1.00 69.23  ? 214 VAL D CB  1 
ATOM   3940 C CG1 . VAL B 2 226 ? 174.586 199.388 200.012 1.00 72.35  ? 214 VAL D CG1 1 
ATOM   3941 C CG2 . VAL B 2 226 ? 176.853 199.242 201.065 1.00 69.94  ? 214 VAL D CG2 1 
ATOM   3942 N N   . TYR B 2 227 ? 172.820 196.960 201.163 1.00 70.99  ? 215 TYR D N   1 
ATOM   3943 C CA  . TYR B 2 227 ? 171.800 196.021 200.715 1.00 70.76  ? 215 TYR D CA  1 
ATOM   3944 C C   . TYR B 2 227 ? 171.205 196.515 199.404 1.00 73.80  ? 215 TYR D C   1 
ATOM   3945 O O   . TYR B 2 227 ? 170.930 197.709 199.249 1.00 82.43  ? 215 TYR D O   1 
ATOM   3946 C CB  . TYR B 2 227 ? 170.694 195.847 201.768 1.00 70.43  ? 215 TYR D CB  1 
ATOM   3947 C CG  . TYR B 2 227 ? 171.131 195.126 203.027 1.00 65.83  ? 215 TYR D CG  1 
ATOM   3948 C CD1 . TYR B 2 227 ? 172.175 195.606 203.804 1.00 69.24  ? 215 TYR D CD1 1 
ATOM   3949 C CD2 . TYR B 2 227 ? 170.498 193.965 203.437 1.00 69.95  ? 215 TYR D CD2 1 
ATOM   3950 C CE1 . TYR B 2 227 ? 172.579 194.950 204.945 1.00 71.28  ? 215 TYR D CE1 1 
ATOM   3951 C CE2 . TYR B 2 227 ? 170.895 193.302 204.581 1.00 76.58  ? 215 TYR D CE2 1 
ATOM   3952 C CZ  . TYR B 2 227 ? 171.937 193.801 205.330 1.00 74.60  ? 215 TYR D CZ  1 
ATOM   3953 O OH  . TYR B 2 227 ? 172.339 193.149 206.471 1.00 76.51  ? 215 TYR D OH  1 
ATOM   3954 N N   . TYR B 2 228 ? 171.006 195.595 198.461 1.00 55.66  ? 216 TYR D N   1 
ATOM   3955 C CA  . TYR B 2 228 ? 170.578 195.937 197.113 1.00 54.81  ? 216 TYR D CA  1 
ATOM   3956 C C   . TYR B 2 228 ? 169.355 195.119 196.724 1.00 57.62  ? 216 TYR D C   1 
ATOM   3957 O O   . TYR B 2 228 ? 169.287 193.920 197.010 1.00 64.31  ? 216 TYR D O   1 
ATOM   3958 C CB  . TYR B 2 228 ? 171.702 195.689 196.105 1.00 60.77  ? 216 TYR D CB  1 
ATOM   3959 C CG  . TYR B 2 228 ? 172.881 196.622 196.255 1.00 61.57  ? 216 TYR D CG  1 
ATOM   3960 C CD1 . TYR B 2 228 ? 173.904 196.337 197.143 1.00 58.19  ? 216 TYR D CD1 1 
ATOM   3961 C CD2 . TYR B 2 228 ? 172.970 197.788 195.509 1.00 69.80  ? 216 TYR D CD2 1 
ATOM   3962 C CE1 . TYR B 2 228 ? 174.983 197.184 197.282 1.00 62.12  ? 216 TYR D CE1 1 
ATOM   3963 C CE2 . TYR B 2 228 ? 174.045 198.642 195.645 1.00 63.08  ? 216 TYR D CE2 1 
ATOM   3964 C CZ  . TYR B 2 228 ? 175.047 198.335 196.533 1.00 62.24  ? 216 TYR D CZ  1 
ATOM   3965 O OH  . TYR B 2 228 ? 176.120 199.183 196.672 1.00 68.41  ? 216 TYR D OH  1 
ATOM   3966 N N   . CYS B 2 229 ? 168.398 195.769 196.063 1.00 74.39  ? 217 CYS D N   1 
ATOM   3967 C CA  . CYS B 2 229 ? 167.208 195.114 195.533 1.00 76.78  ? 217 CYS D CA  1 
ATOM   3968 C C   . CYS B 2 229 ? 167.248 195.167 194.012 1.00 79.80  ? 217 CYS D C   1 
ATOM   3969 O O   . CYS B 2 229 ? 167.439 196.240 193.430 1.00 81.02  ? 217 CYS D O   1 
ATOM   3970 C CB  . CYS B 2 229 ? 165.920 195.765 196.060 1.00 80.60  ? 217 CYS D CB  1 
ATOM   3971 S SG  . CYS B 2 229 ? 165.756 197.566 195.853 1.00 89.52  ? 217 CYS D SG  1 
ATOM   3972 N N   . MET B 2 230 ? 167.070 194.011 193.372 1.00 82.78  ? 218 MET D N   1 
ATOM   3973 C CA  . MET B 2 230 ? 167.198 193.884 191.927 1.00 80.76  ? 218 MET D CA  1 
ATOM   3974 C C   . MET B 2 230 ? 165.944 193.259 191.340 1.00 80.72  ? 218 MET D C   1 
ATOM   3975 O O   . MET B 2 230 ? 165.371 192.334 191.923 1.00 84.10  ? 218 MET D O   1 
ATOM   3976 C CB  . MET B 2 230 ? 168.417 193.033 191.558 1.00 74.12  ? 218 MET D CB  1 
ATOM   3977 C CG  . MET B 2 230 ? 168.989 193.328 190.190 1.00 74.84  ? 218 MET D CG  1 
ATOM   3978 S SD  . MET B 2 230 ? 169.857 191.908 189.512 1.00 79.64  ? 218 MET D SD  1 
ATOM   3979 C CE  . MET B 2 230 ? 168.574 190.668 189.613 1.00 75.89  ? 218 MET D CE  1 
ATOM   3980 N N   . GLN B 2 231 ? 165.566 193.780 190.166 1.00 73.78  ? 219 GLN D N   1 
ATOM   3981 C CA  . GLN B 2 231 ? 164.387 193.253 189.441 1.00 71.71  ? 219 GLN D CA  1 
ATOM   3982 C C   . GLN B 2 231 ? 164.853 192.274 188.375 1.00 77.94  ? 219 GLN D C   1 
ATOM   3983 O O   . GLN B 2 231 ? 166.024 192.357 187.960 1.00 83.74  ? 219 GLN D O   1 
ATOM   3984 C CB  . GLN B 2 231 ? 163.673 194.365 188.685 1.00 66.13  ? 219 GLN D CB  1 
ATOM   3985 C CG  . GLN B 2 231 ? 164.588 195.148 187.759 1.00 62.50  ? 219 GLN D CG  1 
ATOM   3986 C CD  . GLN B 2 231 ? 164.386 194.744 186.321 1.00 71.21  ? 219 GLN D CD  1 
ATOM   3987 O OE1 . GLN B 2 231 ? 163.634 193.821 186.016 1.00 76.66  ? 219 GLN D OE1 1 
ATOM   3988 N NE2 . GLN B 2 231 ? 165.060 195.440 185.421 1.00 76.28  ? 219 GLN D NE2 1 
ATOM   3989 N N   . HIS B 2 232 ? 163.963 191.386 187.950 1.00 81.22  ? 220 HIS D N   1 
ATOM   3990 C CA  . HIS B 2 232 ? 164.283 190.432 186.896 1.00 74.08  ? 220 HIS D CA  1 
ATOM   3991 C C   . HIS B 2 232 ? 163.094 190.195 185.973 1.00 74.09  ? 220 HIS D C   1 
ATOM   3992 O O   . HIS B 2 232 ? 162.963 189.113 185.391 1.00 81.13  ? 220 HIS D O   1 
ATOM   3993 C CB  . HIS B 2 232 ? 164.761 189.108 187.491 1.00 71.49  ? 220 HIS D CB  1 
ATOM   3994 C CG  . HIS B 2 232 ? 165.665 188.331 186.589 1.00 71.72  ? 220 HIS D CG  1 
ATOM   3995 N ND1 . HIS B 2 232 ? 165.430 188.193 185.240 1.00 76.34  ? 220 HIS D ND1 1 
ATOM   3996 C CD2 . HIS B 2 232 ? 166.803 187.646 186.845 1.00 75.38  ? 220 HIS D CD2 1 
ATOM   3997 C CE1 . HIS B 2 232 ? 166.386 187.458 184.702 1.00 77.80  ? 220 HIS D CE1 1 
ATOM   3998 N NE2 . HIS B 2 232 ? 167.232 187.113 185.655 1.00 76.18  ? 220 HIS D NE2 1 
ATOM   3999 N N   . LEU B 2 233 ? 162.216 191.188 185.829 1.00 66.54  ? 221 LEU D N   1 
ATOM   4000 C CA  . LEU B 2 233 ? 161.059 191.018 184.959 1.00 64.49  ? 221 LEU D CA  1 
ATOM   4001 C C   . LEU B 2 233 ? 161.444 191.084 183.486 1.00 64.55  ? 221 LEU D C   1 
ATOM   4002 O O   . LEU B 2 233 ? 160.970 190.272 182.684 1.00 67.65  ? 221 LEU D O   1 
ATOM   4003 C CB  . LEU B 2 233 ? 160.001 192.072 185.281 1.00 70.95  ? 221 LEU D CB  1 
ATOM   4004 C CG  . LEU B 2 233 ? 158.656 191.902 184.577 1.00 75.27  ? 221 LEU D CG  1 
ATOM   4005 C CD1 . LEU B 2 233 ? 157.975 190.628 185.041 1.00 73.45  ? 221 LEU D CD1 1 
ATOM   4006 C CD2 . LEU B 2 233 ? 157.765 193.105 184.828 1.00 76.32  ? 221 LEU D CD2 1 
ATOM   4007 N N   . GLU B 2 234 ? 162.301 192.031 183.112 1.00 74.56  ? 222 GLU D N   1 
ATOM   4008 C CA  . GLU B 2 234 ? 162.694 192.190 181.719 1.00 71.95  ? 222 GLU D CA  1 
ATOM   4009 C C   . GLU B 2 234 ? 164.022 192.930 181.659 1.00 69.97  ? 222 GLU D C   1 
ATOM   4010 O O   . GLU B 2 234 ? 164.307 193.774 182.511 1.00 72.13  ? 222 GLU D O   1 
ATOM   4011 C CB  . GLU B 2 234 ? 161.624 192.944 180.923 1.00 80.61  ? 222 GLU D CB  1 
ATOM   4012 C CG  . GLU B 2 234 ? 161.597 192.613 179.439 1.00 83.73  ? 222 GLU D CG  1 
ATOM   4013 C CD  . GLU B 2 234 ? 162.510 193.504 178.622 1.00 86.43  ? 222 GLU D CD  1 
ATOM   4014 O OE1 . GLU B 2 234 ? 162.228 194.717 178.525 1.00 83.82  ? 222 GLU D OE1 1 
ATOM   4015 O OE2 . GLU B 2 234 ? 163.510 192.992 178.076 1.00 86.15  ? 222 GLU D OE2 1 
ATOM   4016 N N   . TYR B 2 235 ? 164.824 192.605 180.652 1.00 71.51  ? 223 TYR D N   1 
ATOM   4017 C CA  . TYR B 2 235 ? 166.133 193.217 180.513 1.00 77.41  ? 223 TYR D CA  1 
ATOM   4018 C C   . TYR B 2 235 ? 166.002 194.684 180.103 1.00 77.17  ? 223 TYR D C   1 
ATOM   4019 O O   . TYR B 2 235 ? 165.053 195.061 179.411 1.00 81.40  ? 223 TYR D O   1 
ATOM   4020 C CB  . TYR B 2 235 ? 166.968 192.458 179.486 1.00 80.36  ? 223 TYR D CB  1 
ATOM   4021 C CG  . TYR B 2 235 ? 167.202 191.010 179.848 1.00 78.16  ? 223 TYR D CG  1 
ATOM   4022 C CD1 . TYR B 2 235 ? 166.276 190.032 179.517 1.00 80.19  ? 223 TYR D CD1 1 
ATOM   4023 C CD2 . TYR B 2 235 ? 168.345 190.624 180.530 1.00 73.92  ? 223 TYR D CD2 1 
ATOM   4024 C CE1 . TYR B 2 235 ? 166.485 188.711 179.852 1.00 83.07  ? 223 TYR D CE1 1 
ATOM   4025 C CE2 . TYR B 2 235 ? 168.562 189.308 180.870 1.00 77.22  ? 223 TYR D CE2 1 
ATOM   4026 C CZ  . TYR B 2 235 ? 167.630 188.355 180.528 1.00 83.22  ? 223 TYR D CZ  1 
ATOM   4027 O OH  . TYR B 2 235 ? 167.843 187.037 180.863 1.00 82.77  ? 223 TYR D OH  1 
ATOM   4028 N N   . PRO B 2 236 ? 166.907 195.604 180.518 1.00 76.87  ? 224 PRO D N   1 
ATOM   4029 C CA  . PRO B 2 236 ? 168.148 195.268 181.200 1.00 78.41  ? 224 PRO D CA  1 
ATOM   4030 C C   . PRO B 2 236 ? 167.957 195.273 182.721 1.00 82.73  ? 224 PRO D C   1 
ATOM   4031 O O   . PRO B 2 236 ? 167.037 195.910 183.195 1.00 81.69  ? 224 PRO D O   1 
ATOM   4032 C CB  . PRO B 2 236 ? 169.044 196.440 180.794 1.00 77.90  ? 224 PRO D CB  1 
ATOM   4033 C CG  . PRO B 2 236 ? 168.114 197.622 180.810 1.00 80.07  ? 224 PRO D CG  1 
ATOM   4034 C CD  . PRO B 2 236 ? 166.786 197.060 180.349 1.00 81.74  ? 224 PRO D CD  1 
ATOM   4035 N N   . LEU B 2 237 ? 168.808 194.545 183.446 1.00 81.42  ? 225 LEU D N   1 
ATOM   4036 C CA  . LEU B 2 237 ? 168.621 194.444 184.914 1.00 81.24  ? 225 LEU D CA  1 
ATOM   4037 C C   . LEU B 2 237 ? 168.812 195.831 185.526 1.00 76.26  ? 225 LEU D C   1 
ATOM   4038 O O   . LEU B 2 237 ? 169.768 196.521 185.137 1.00 78.21  ? 225 LEU D O   1 
ATOM   4039 C CB  . LEU B 2 237 ? 169.646 193.444 185.455 1.00 82.25  ? 225 LEU D CB  1 
ATOM   4040 C CG  . LEU B 2 237 ? 169.731 192.126 184.689 1.00 78.23  ? 225 LEU D CG  1 
ATOM   4041 C CD1 . LEU B 2 237 ? 170.925 191.308 185.152 1.00 71.49  ? 225 LEU D CD1 1 
ATOM   4042 C CD2 . LEU B 2 237 ? 168.447 191.328 184.844 1.00 79.63  ? 225 LEU D CD2 1 
ATOM   4043 N N   . THR B 2 238 ? 167.937 196.210 186.457 1.00 78.76  ? 226 THR D N   1 
ATOM   4044 C CA  . THR B 2 238 ? 168.046 197.527 187.131 1.00 81.17  ? 226 THR D CA  1 
ATOM   4045 C C   . THR B 2 238 ? 168.138 197.294 188.637 1.00 84.25  ? 226 THR D C   1 
ATOM   4046 O O   . THR B 2 238 ? 167.319 196.520 189.165 1.00 87.14  ? 226 THR D O   1 
ATOM   4047 C CB  . THR B 2 238 ? 166.882 198.450 186.757 1.00 81.73  ? 226 THR D CB  1 
ATOM   4048 O OG1 . THR B 2 238 ? 165.751 198.094 187.554 1.00 85.30  ? 226 THR D OG1 1 
ATOM   4049 C CG2 . THR B 2 238 ? 166.516 198.376 185.291 1.00 84.02  ? 226 THR D CG2 1 
ATOM   4050 N N   . PHE B 2 239 ? 169.101 197.937 189.290 1.00 87.62  ? 227 PHE D N   1 
ATOM   4051 C CA  . PHE B 2 239 ? 169.281 197.769 190.751 1.00 85.67  ? 227 PHE D CA  1 
ATOM   4052 C C   . PHE B 2 239 ? 168.798 199.029 191.467 1.00 87.01  ? 227 PHE D C   1 
ATOM   4053 O O   . PHE B 2 239 ? 168.154 199.873 190.822 1.00 88.47  ? 227 PHE D O   1 
ATOM   4054 C CB  . PHE B 2 239 ? 170.752 197.505 191.080 1.00 81.73  ? 227 PHE D CB  1 
ATOM   4055 C CG  . PHE B 2 239 ? 171.421 196.400 190.302 1.00 80.31  ? 227 PHE D CG  1 
ATOM   4056 C CD1 . PHE B 2 239 ? 171.637 196.514 188.938 1.00 86.00  ? 227 PHE D CD1 1 
ATOM   4057 C CD2 . PHE B 2 239 ? 171.863 195.255 190.942 1.00 79.47  ? 227 PHE D CD2 1 
ATOM   4058 C CE1 . PHE B 2 239 ? 172.258 195.498 188.229 1.00 89.62  ? 227 PHE D CE1 1 
ATOM   4059 C CE2 . PHE B 2 239 ? 172.488 194.242 190.234 1.00 83.89  ? 227 PHE D CE2 1 
ATOM   4060 C CZ  . PHE B 2 239 ? 172.684 194.365 188.879 1.00 87.96  ? 227 PHE D CZ  1 
ATOM   4061 N N   . GLY B 2 240 ? 169.069 199.132 192.765 1.00 91.85  ? 228 GLY D N   1 
ATOM   4062 C CA  . GLY B 2 240 ? 168.728 200.311 193.524 1.00 91.58  ? 228 GLY D CA  1 
ATOM   4063 C C   . GLY B 2 240 ? 169.957 201.141 193.867 1.00 95.56  ? 228 GLY D C   1 
ATOM   4064 O O   . GLY B 2 240 ? 171.095 200.787 193.567 1.00 98.34  ? 228 GLY D O   1 
ATOM   4065 N N   . ALA B 2 241 ? 169.699 202.281 194.510 1.00 100.66 ? 229 ALA D N   1 
ATOM   4066 C CA  . ALA B 2 241 ? 170.789 203.181 194.875 1.00 100.49 ? 229 ALA D CA  1 
ATOM   4067 C C   . ALA B 2 241 ? 171.705 202.554 195.918 1.00 100.21 ? 229 ALA D C   1 
ATOM   4068 O O   . ALA B 2 241 ? 172.933 202.646 195.808 1.00 99.34  ? 229 ALA D O   1 
ATOM   4069 C CB  . ALA B 2 241 ? 170.226 204.508 195.383 1.00 98.87  ? 229 ALA D CB  1 
ATOM   4070 N N   . GLY B 2 242 ? 171.132 201.910 196.931 1.00 105.61 ? 230 GLY D N   1 
ATOM   4071 C CA  . GLY B 2 242 ? 171.922 201.304 197.983 1.00 104.37 ? 230 GLY D CA  1 
ATOM   4072 C C   . GLY B 2 242 ? 171.549 201.793 199.368 1.00 106.19 ? 230 GLY D C   1 
ATOM   4073 O O   . GLY B 2 242 ? 171.541 203.000 199.627 1.00 107.98 ? 230 GLY D O   1 
ATOM   4074 N N   . THR B 2 243 ? 171.238 200.863 200.266 1.00 95.87  ? 231 THR D N   1 
ATOM   4075 C CA  . THR B 2 243 ? 170.888 201.174 201.645 1.00 95.78  ? 231 THR D CA  1 
ATOM   4076 C C   . THR B 2 243 ? 171.947 200.596 202.574 1.00 96.72  ? 231 THR D C   1 
ATOM   4077 O O   . THR B 2 243 ? 172.302 199.418 202.458 1.00 97.96  ? 231 THR D O   1 
ATOM   4078 C CB  . THR B 2 243 ? 169.512 200.611 201.999 1.00 93.96  ? 231 THR D CB  1 
ATOM   4079 O OG1 . THR B 2 243 ? 168.549 201.072 201.044 1.00 92.31  ? 231 THR D OG1 1 
ATOM   4080 C CG2 . THR B 2 243 ? 169.096 201.063 203.387 1.00 95.26  ? 231 THR D CG2 1 
ATOM   4081 N N   . LYS B 2 244 ? 172.444 201.418 203.492 1.00 97.16  ? 232 LYS D N   1 
ATOM   4082 C CA  . LYS B 2 244 ? 173.515 201.028 204.395 1.00 97.76  ? 232 LYS D CA  1 
ATOM   4083 C C   . LYS B 2 244 ? 172.997 200.878 205.819 1.00 99.15  ? 232 LYS D C   1 
ATOM   4084 O O   . LYS B 2 244 ? 172.012 201.507 206.213 1.00 104.90 ? 232 LYS D O   1 
ATOM   4085 C CB  . LYS B 2 244 ? 174.654 202.051 204.382 1.00 95.91  ? 232 LYS D CB  1 
ATOM   4086 C CG  . LYS B 2 244 ? 175.565 201.965 203.174 1.00 99.81  ? 232 LYS D CG  1 
ATOM   4087 C CD  . LYS B 2 244 ? 176.634 203.046 203.214 1.00 101.18 ? 232 LYS D CD  1 
ATOM   4088 C CE  . LYS B 2 244 ? 176.043 204.399 203.578 1.00 101.52 ? 232 LYS D CE  1 
ATOM   4089 N NZ  . LYS B 2 244 ? 177.079 205.468 203.610 1.00 99.86  ? 232 LYS D NZ  1 
ATOM   4090 N N   . LEU B 2 245 ? 173.678 200.029 206.584 1.00 87.23  ? 233 LEU D N   1 
ATOM   4091 C CA  . LEU B 2 245 ? 173.450 199.881 208.013 1.00 86.18  ? 233 LEU D CA  1 
ATOM   4092 C C   . LEU B 2 245 ? 174.775 200.074 208.734 1.00 92.28  ? 233 LEU D C   1 
ATOM   4093 O O   . LEU B 2 245 ? 175.782 199.466 208.358 1.00 96.00  ? 233 LEU D O   1 
ATOM   4094 C CB  . LEU B 2 245 ? 172.856 198.511 208.346 1.00 85.92  ? 233 LEU D CB  1 
ATOM   4095 C CG  . LEU B 2 245 ? 171.378 198.310 208.020 1.00 90.89  ? 233 LEU D CG  1 
ATOM   4096 C CD1 . LEU B 2 245 ? 171.201 197.857 206.583 1.00 91.74  ? 233 LEU D CD1 1 
ATOM   4097 C CD2 . LEU B 2 245 ? 170.747 197.315 208.979 1.00 93.39  ? 233 LEU D CD2 1 
ATOM   4098 N N   . GLU B 2 246 ? 174.775 200.917 209.761 1.00 112.03 ? 234 GLU D N   1 
ATOM   4099 C CA  . GLU B 2 246 ? 175.975 201.217 210.523 1.00 113.60 ? 234 GLU D CA  1 
ATOM   4100 C C   . GLU B 2 246 ? 175.728 200.969 212.005 1.00 115.94 ? 234 GLU D C   1 
ATOM   4101 O O   . GLU B 2 246 ? 174.602 201.076 212.498 1.00 117.62 ? 234 GLU D O   1 
ATOM   4102 C CB  . GLU B 2 246 ? 176.428 202.665 210.303 1.00 112.59 ? 234 GLU D CB  1 
ATOM   4103 C CG  . GLU B 2 246 ? 176.470 203.090 208.845 1.00 115.05 ? 234 GLU D CG  1 
ATOM   4104 C CD  . GLU B 2 246 ? 176.052 204.533 208.647 1.00 119.12 ? 234 GLU D CD  1 
ATOM   4105 O OE1 . GLU B 2 246 ? 176.901 205.430 208.834 1.00 119.54 ? 234 GLU D OE1 1 
ATOM   4106 O OE2 . GLU B 2 246 ? 174.874 204.771 208.308 1.00 118.85 ? 234 GLU D OE2 1 
ATOM   4107 N N   . LEU B 2 247 ? 176.802 200.633 212.712 1.00 110.81 ? 235 LEU D N   1 
ATOM   4108 C CA  . LEU B 2 247 ? 176.724 200.346 214.139 1.00 110.61 ? 235 LEU D CA  1 
ATOM   4109 C C   . LEU B 2 247 ? 176.600 201.630 214.953 1.00 111.44 ? 235 LEU D C   1 
ATOM   4110 O O   . LEU B 2 247 ? 176.209 201.603 216.120 1.00 108.99 ? 235 LEU D O   1 
ATOM   4111 C CB  . LEU B 2 247 ? 177.950 199.552 214.593 1.00 111.04 ? 235 LEU D CB  1 
ATOM   4112 C CG  . LEU B 2 247 ? 179.248 200.344 214.767 1.00 111.93 ? 235 LEU D CG  1 
ATOM   4113 C CD1 . LEU B 2 247 ? 180.099 199.742 215.875 1.00 109.47 ? 235 LEU D CD1 1 
ATOM   4114 C CD2 . LEU B 2 247 ? 180.028 200.401 213.462 1.00 110.44 ? 235 LEU D CD2 1 
ATOM   4115 N N   . LEU C 3 5   ? 155.489 185.031 178.329 1.00 98.92  ? 5   LEU A N   1 
ATOM   4116 C CA  . LEU C 3 5   ? 156.583 184.339 178.999 1.00 98.70  ? 5   LEU A CA  1 
ATOM   4117 C C   . LEU C 3 5   ? 157.619 185.323 179.526 1.00 99.59  ? 5   LEU A C   1 
ATOM   4118 O O   . LEU C 3 5   ? 157.935 186.316 178.871 1.00 102.20 ? 5   LEU A O   1 
ATOM   4119 C CB  . LEU C 3 5   ? 157.249 183.340 178.051 1.00 95.42  ? 5   LEU A CB  1 
ATOM   4120 C CG  . LEU C 3 5   ? 156.475 182.057 177.750 1.00 97.90  ? 5   LEU A CG  1 
ATOM   4121 C CD1 . LEU C 3 5   ? 157.330 181.100 176.938 1.00 96.81  ? 5   LEU A CD1 1 
ATOM   4122 C CD2 . LEU C 3 5   ? 156.000 181.399 179.035 1.00 100.31 ? 5   LEU A CD2 1 
ATOM   4123 N N   . SER C 3 6   ? 158.146 185.043 180.715 1.00 92.96  ? 6   SER A N   1 
ATOM   4124 C CA  . SER C 3 6   ? 159.185 185.865 181.308 1.00 89.59  ? 6   SER A CA  1 
ATOM   4125 C C   . SER C 3 6   ? 160.559 185.368 180.864 1.00 95.39  ? 6   SER A C   1 
ATOM   4126 O O   . SER C 3 6   ? 160.684 184.411 180.096 1.00 101.63 ? 6   SER A O   1 
ATOM   4127 C CB  . SER C 3 6   ? 159.059 185.863 182.829 1.00 92.30  ? 6   SER A CB  1 
ATOM   4128 O OG  . SER C 3 6   ? 157.698 185.864 183.221 1.00 91.79  ? 6   SER A OG  1 
ATOM   4129 N N   . ALA C 3 7   ? 161.609 186.034 181.348 1.00 88.33  ? 7   ALA A N   1 
ATOM   4130 C CA  . ALA C 3 7   ? 162.965 185.622 180.998 1.00 91.54  ? 7   ALA A CA  1 
ATOM   4131 C C   . ALA C 3 7   ? 163.282 184.239 181.551 1.00 95.02  ? 7   ALA A C   1 
ATOM   4132 O O   . ALA C 3 7   ? 163.890 183.407 180.863 1.00 96.73  ? 7   ALA A O   1 
ATOM   4133 C CB  . ALA C 3 7   ? 163.974 186.649 181.510 1.00 84.27  ? 7   ALA A CB  1 
ATOM   4134 N N   . GLU C 3 8   ? 162.874 183.975 182.793 1.00 87.44  ? 8   GLU A N   1 
ATOM   4135 C CA  . GLU C 3 8   ? 163.158 182.686 183.413 1.00 89.14  ? 8   GLU A CA  1 
ATOM   4136 C C   . GLU C 3 8   ? 162.451 181.550 182.683 1.00 90.83  ? 8   GLU A C   1 
ATOM   4137 O O   . GLU C 3 8   ? 163.033 180.476 182.483 1.00 95.96  ? 8   GLU A O   1 
ATOM   4138 C CB  . GLU C 3 8   ? 162.753 182.724 184.884 1.00 89.00  ? 8   GLU A CB  1 
ATOM   4139 C CG  . GLU C 3 8   ? 163.093 184.038 185.565 1.00 89.00  ? 8   GLU A CG  1 
ATOM   4140 C CD  . GLU C 3 8   ? 163.708 183.845 186.934 1.00 92.62  ? 8   GLU A CD  1 
ATOM   4141 O OE1 . GLU C 3 8   ? 164.096 182.704 187.257 1.00 92.24  ? 8   GLU A OE1 1 
ATOM   4142 O OE2 . GLU C 3 8   ? 163.803 184.835 187.688 1.00 91.58  ? 8   GLU A OE2 1 
ATOM   4143 N N   . ASP C 3 9   ? 161.199 181.767 182.276 1.00 83.77  ? 9   ASP A N   1 
ATOM   4144 C CA  . ASP C 3 9   ? 160.481 180.742 181.527 1.00 89.80  ? 9   ASP A CA  1 
ATOM   4145 C C   . ASP C 3 9   ? 161.151 180.469 180.186 1.00 92.48  ? 9   ASP A C   1 
ATOM   4146 O O   . ASP C 3 9   ? 161.242 179.315 179.750 1.00 98.49  ? 9   ASP A O   1 
ATOM   4147 C CB  . ASP C 3 9   ? 159.026 181.164 181.329 1.00 92.59  ? 9   ASP A CB  1 
ATOM   4148 C CG  . ASP C 3 9   ? 158.051 180.037 181.606 1.00 97.67  ? 9   ASP A CG  1 
ATOM   4149 O OD1 . ASP C 3 9   ? 158.386 178.872 181.307 1.00 97.36  ? 9   ASP A OD1 1 
ATOM   4150 O OD2 . ASP C 3 9   ? 156.949 180.317 182.123 1.00 95.91  ? 9   ASP A OD2 1 
ATOM   4151 N N   . LYS C 3 10  ? 161.629 181.520 179.517 1.00 79.19  ? 10  LYS A N   1 
ATOM   4152 C CA  . LYS C 3 10  ? 162.319 181.335 178.246 1.00 83.62  ? 10  LYS A CA  1 
ATOM   4153 C C   . LYS C 3 10  ? 163.614 180.552 178.430 1.00 87.11  ? 10  LYS A C   1 
ATOM   4154 O O   . LYS C 3 10  ? 163.947 179.680 177.616 1.00 91.24  ? 10  LYS A O   1 
ATOM   4155 C CB  . LYS C 3 10  ? 162.595 182.693 177.602 1.00 83.53  ? 10  LYS A CB  1 
ATOM   4156 C CG  . LYS C 3 10  ? 161.457 183.206 176.736 1.00 86.77  ? 10  LYS A CG  1 
ATOM   4157 C CD  . LYS C 3 10  ? 161.939 184.258 175.752 1.00 85.43  ? 10  LYS A CD  1 
ATOM   4158 C CE  . LYS C 3 10  ? 162.004 185.629 176.401 1.00 84.03  ? 10  LYS A CE  1 
ATOM   4159 N NZ  . LYS C 3 10  ? 160.655 186.117 176.796 1.00 85.11  ? 10  LYS A NZ  1 
ATOM   4160 N N   . ALA C 3 11  ? 164.359 180.850 179.496 1.00 75.34  ? 11  ALA A N   1 
ATOM   4161 C CA  . ALA C 3 11  ? 165.581 180.099 179.762 1.00 70.14  ? 11  ALA A CA  1 
ATOM   4162 C C   . ALA C 3 11  ? 165.273 178.641 180.084 1.00 76.20  ? 11  ALA A C   1 
ATOM   4163 O O   . ALA C 3 11  ? 166.021 177.738 179.689 1.00 85.52  ? 11  ALA A O   1 
ATOM   4164 C CB  . ALA C 3 11  ? 166.363 180.755 180.896 1.00 69.63  ? 11  ALA A CB  1 
ATOM   4165 N N   . ALA C 3 12  ? 164.173 178.391 180.798 1.00 72.21  ? 12  ALA A N   1 
ATOM   4166 C CA  . ALA C 3 12  ? 163.757 177.015 181.051 1.00 76.22  ? 12  ALA A CA  1 
ATOM   4167 C C   . ALA C 3 12  ? 163.414 176.296 179.752 1.00 78.39  ? 12  ALA A C   1 
ATOM   4168 O O   . ALA C 3 12  ? 163.743 175.114 179.576 1.00 82.95  ? 12  ALA A O   1 
ATOM   4169 C CB  . ALA C 3 12  ? 162.565 176.993 182.007 1.00 77.31  ? 12  ALA A CB  1 
ATOM   4170 N N   . VAL C 3 13  ? 162.745 176.994 178.833 1.00 74.35  ? 13  VAL A N   1 
ATOM   4171 C CA  . VAL C 3 13  ? 162.440 176.414 177.529 1.00 75.68  ? 13  VAL A CA  1 
ATOM   4172 C C   . VAL C 3 13  ? 163.726 176.055 176.795 1.00 71.40  ? 13  VAL A C   1 
ATOM   4173 O O   . VAL C 3 13  ? 163.838 174.980 176.191 1.00 77.44  ? 13  VAL A O   1 
ATOM   4174 C CB  . VAL C 3 13  ? 161.571 177.383 176.707 1.00 80.69  ? 13  VAL A CB  1 
ATOM   4175 C CG1 . VAL C 3 13  ? 161.587 177.003 175.235 1.00 80.68  ? 13  VAL A CG1 1 
ATOM   4176 C CG2 . VAL C 3 13  ? 160.152 177.409 177.245 1.00 78.86  ? 13  VAL A CG2 1 
ATOM   4177 N N   . GLU C 3 14  ? 164.715 176.949 176.837 1.00 71.18  ? 14  GLU A N   1 
ATOM   4178 C CA  . GLU C 3 14  ? 165.988 176.669 176.177 1.00 76.99  ? 14  GLU A CA  1 
ATOM   4179 C C   . GLU C 3 14  ? 166.682 175.465 176.805 1.00 79.88  ? 14  GLU A C   1 
ATOM   4180 O O   . GLU C 3 14  ? 167.282 174.640 176.100 1.00 89.23  ? 14  GLU A O   1 
ATOM   4181 C CB  . GLU C 3 14  ? 166.886 177.903 176.232 1.00 81.62  ? 14  GLU A CB  1 
ATOM   4182 C CG  . GLU C 3 14  ? 168.295 177.673 175.724 1.00 84.27  ? 14  GLU A CG  1 
ATOM   4183 C CD  . GLU C 3 14  ? 168.940 178.946 175.219 1.00 88.74  ? 14  GLU A CD  1 
ATOM   4184 O OE1 . GLU C 3 14  ? 168.600 180.029 175.738 1.00 90.65  ? 14  GLU A OE1 1 
ATOM   4185 O OE2 . GLU C 3 14  ? 169.785 178.865 174.303 1.00 89.14  ? 14  GLU A OE2 1 
ATOM   4186 N N   . ARG C 3 15  ? 166.612 175.350 178.133 1.00 71.02  ? 15  ARG A N   1 
ATOM   4187 C CA  . ARG C 3 15  ? 167.178 174.186 178.811 1.00 75.08  ? 15  ARG A CA  1 
ATOM   4188 C C   . ARG C 3 15  ? 166.506 172.900 178.348 1.00 78.81  ? 15  ARG A C   1 
ATOM   4189 O O   . ARG C 3 15  ? 167.179 171.892 178.086 1.00 82.33  ? 15  ARG A O   1 
ATOM   4190 C CB  . ARG C 3 15  ? 167.037 174.348 180.324 1.00 72.22  ? 15  ARG A CB  1 
ATOM   4191 C CG  . ARG C 3 15  ? 167.588 173.188 181.130 1.00 73.22  ? 15  ARG A CG  1 
ATOM   4192 C CD  . ARG C 3 15  ? 167.512 173.472 182.620 1.00 72.01  ? 15  ARG A CD  1 
ATOM   4193 N NE  . ARG C 3 15  ? 168.095 172.396 183.411 1.00 74.77  ? 15  ARG A NE  1 
ATOM   4194 C CZ  . ARG C 3 15  ? 169.388 172.279 183.677 1.00 75.84  ? 15  ARG A CZ  1 
ATOM   4195 N NH1 . ARG C 3 15  ? 170.268 173.158 183.227 1.00 77.91  ? 15  ARG A NH1 1 
ATOM   4196 N NH2 . ARG C 3 15  ? 169.810 171.255 184.412 1.00 69.12  ? 15  ARG A NH2 1 
ATOM   4197 N N   . SER C 3 16  ? 165.176 172.919 178.243 1.00 78.23  ? 16  SER A N   1 
ATOM   4198 C CA  . SER C 3 16  ? 164.458 171.743 177.762 1.00 78.15  ? 16  SER A CA  1 
ATOM   4199 C C   . SER C 3 16  ? 164.871 171.390 176.339 1.00 79.80  ? 16  SER A C   1 
ATOM   4200 O O   . SER C 3 16  ? 165.032 170.210 176.007 1.00 84.78  ? 16  SER A O   1 
ATOM   4201 C CB  . SER C 3 16  ? 162.952 171.976 177.840 1.00 77.78  ? 16  SER A CB  1 
ATOM   4202 O OG  . SER C 3 16  ? 162.269 171.169 176.899 1.00 80.22  ? 16  SER A OG  1 
ATOM   4203 N N   . LYS C 3 17  ? 165.047 172.400 175.484 1.00 79.34  ? 17  LYS A N   1 
ATOM   4204 C CA  . LYS C 3 17  ? 165.474 172.136 174.111 1.00 80.66  ? 17  LYS A CA  1 
ATOM   4205 C C   . LYS C 3 17  ? 166.860 171.499 174.070 1.00 80.34  ? 17  LYS A C   1 
ATOM   4206 O O   . LYS C 3 17  ? 167.100 170.566 173.292 1.00 86.49  ? 17  LYS A O   1 
ATOM   4207 C CB  . LYS C 3 17  ? 165.456 173.426 173.292 1.00 84.90  ? 17  LYS A CB  1 
ATOM   4208 C CG  . LYS C 3 17  ? 164.091 174.085 173.196 1.00 88.03  ? 17  LYS A CG  1 
ATOM   4209 C CD  . LYS C 3 17  ? 163.120 173.239 172.395 1.00 85.96  ? 17  LYS A CD  1 
ATOM   4210 C CE  . LYS C 3 17  ? 161.775 173.931 172.256 1.00 84.08  ? 17  LYS A CE  1 
ATOM   4211 N NZ  . LYS C 3 17  ? 161.921 175.410 172.179 1.00 83.47  ? 17  LYS A NZ  1 
ATOM   4212 N N   . MET C 3 18  ? 167.788 171.995 174.892 1.00 75.92  ? 18  MET A N   1 
ATOM   4213 C CA  . MET C 3 18  ? 169.125 171.404 174.922 1.00 73.52  ? 18  MET A CA  1 
ATOM   4214 C C   . MET C 3 18  ? 169.078 169.955 175.393 1.00 79.95  ? 18  MET A C   1 
ATOM   4215 O O   . MET C 3 18  ? 169.750 169.080 174.823 1.00 90.02  ? 18  MET A O   1 
ATOM   4216 C CB  . MET C 3 18  ? 170.050 172.226 175.818 1.00 76.08  ? 18  MET A CB  1 
ATOM   4217 C CG  . MET C 3 18  ? 170.743 173.372 175.108 1.00 80.94  ? 18  MET A CG  1 
ATOM   4218 S SD  . MET C 3 18  ? 171.660 174.435 176.237 1.00 94.47  ? 18  MET A SD  1 
ATOM   4219 C CE  . MET C 3 18  ? 170.671 174.285 177.722 1.00 85.86  ? 18  MET A CE  1 
ATOM   4220 N N   . ILE C 3 19  ? 168.287 169.681 176.433 1.00 77.56  ? 19  ILE A N   1 
ATOM   4221 C CA  . ILE C 3 19  ? 168.174 168.310 176.922 1.00 80.10  ? 19  ILE A CA  1 
ATOM   4222 C C   . ILE C 3 19  ? 167.568 167.414 175.848 1.00 79.12  ? 19  ILE A C   1 
ATOM   4223 O O   . ILE C 3 19  ? 167.974 166.257 175.681 1.00 85.54  ? 19  ILE A O   1 
ATOM   4224 C CB  . ILE C 3 19  ? 167.361 168.266 178.228 1.00 81.41  ? 19  ILE A CB  1 
ATOM   4225 C CG1 . ILE C 3 19  ? 168.078 169.050 179.326 1.00 82.62  ? 19  ILE A CG1 1 
ATOM   4226 C CG2 . ILE C 3 19  ? 167.172 166.837 178.683 1.00 79.57  ? 19  ILE A CG2 1 
ATOM   4227 C CD1 . ILE C 3 19  ? 167.311 169.113 180.628 1.00 79.71  ? 19  ILE A CD1 1 
ATOM   4228 N N   . ASP C 3 20  ? 166.595 167.936 175.097 1.00 80.16  ? 20  ASP A N   1 
ATOM   4229 C CA  . ASP C 3 20  ? 165.993 167.155 174.022 1.00 81.94  ? 20  ASP A CA  1 
ATOM   4230 C C   . ASP C 3 20  ? 167.008 166.841 172.929 1.00 80.33  ? 20  ASP A C   1 
ATOM   4231 O O   . ASP C 3 20  ? 167.031 165.726 172.395 1.00 85.69  ? 20  ASP A O   1 
ATOM   4232 C CB  . ASP C 3 20  ? 164.790 167.898 173.443 1.00 84.57  ? 20  ASP A CB  1 
ATOM   4233 C CG  . ASP C 3 20  ? 163.496 167.548 174.150 1.00 88.17  ? 20  ASP A CG  1 
ATOM   4234 O OD1 . ASP C 3 20  ? 163.355 166.391 174.596 1.00 90.25  ? 20  ASP A OD1 1 
ATOM   4235 O OD2 . ASP C 3 20  ? 162.620 168.430 174.262 1.00 86.19  ? 20  ASP A OD2 1 
ATOM   4236 N N   . ARG C 3 21  ? 167.850 167.816 172.577 1.00 85.70  ? 21  ARG A N   1 
ATOM   4237 C CA  . ARG C 3 21  ? 168.898 167.563 171.590 1.00 86.40  ? 21  ARG A CA  1 
ATOM   4238 C C   . ARG C 3 21  ? 169.831 166.455 172.058 1.00 88.51  ? 21  ARG A C   1 
ATOM   4239 O O   . ARG C 3 21  ? 170.157 165.533 171.296 1.00 91.83  ? 21  ARG A O   1 
ATOM   4240 C CB  . ARG C 3 21  ? 169.697 168.838 171.321 1.00 86.88  ? 21  ARG A CB  1 
ATOM   4241 C CG  . ARG C 3 21  ? 169.288 169.596 170.074 1.00 88.15  ? 21  ARG A CG  1 
ATOM   4242 C CD  . ARG C 3 21  ? 170.507 169.955 169.239 1.00 89.32  ? 21  ARG A CD  1 
ATOM   4243 N NE  . ARG C 3 21  ? 170.852 171.368 169.337 1.00 95.62  ? 21  ARG A NE  1 
ATOM   4244 C CZ  . ARG C 3 21  ? 172.086 171.827 169.488 1.00 96.67  ? 21  ARG A CZ  1 
ATOM   4245 N NH1 . ARG C 3 21  ? 173.124 171.009 169.560 1.00 95.87  ? 21  ARG A NH1 1 
ATOM   4246 N NH2 . ARG C 3 21  ? 172.286 173.140 169.567 1.00 92.50  ? 21  ARG A NH2 1 
ATOM   4247 N N   . ASN C 3 22  ? 170.271 166.532 173.317 1.00 84.51  ? 22  ASN A N   1 
ATOM   4248 C CA  . ASN C 3 22  ? 171.175 165.510 173.838 1.00 81.32  ? 22  ASN A CA  1 
ATOM   4249 C C   . ASN C 3 22  ? 170.515 164.136 173.840 1.00 86.41  ? 22  ASN A C   1 
ATOM   4250 O O   . ASN C 3 22  ? 171.142 163.133 173.470 1.00 91.64  ? 22  ASN A O   1 
ATOM   4251 C CB  . ASN C 3 22  ? 171.637 165.886 175.244 1.00 81.90  ? 22  ASN A CB  1 
ATOM   4252 C CG  . ASN C 3 22  ? 173.053 165.435 175.531 1.00 89.41  ? 22  ASN A CG  1 
ATOM   4253 O OD1 . ASN C 3 22  ? 173.939 165.562 174.687 1.00 91.16  ? 22  ASN A OD1 1 
ATOM   4254 N ND2 . ASN C 3 22  ? 173.274 164.901 176.726 1.00 93.22  ? 22  ASN A ND2 1 
ATOM   4255 N N   . LEU C 3 23  ? 169.244 164.072 174.247 1.00 84.53  ? 23  LEU A N   1 
ATOM   4256 C CA  . LEU C 3 23  ? 168.531 162.799 174.274 1.00 79.93  ? 23  LEU A CA  1 
ATOM   4257 C C   . LEU C 3 23  ? 168.391 162.207 172.879 1.00 81.58  ? 23  LEU A C   1 
ATOM   4258 O O   . LEU C 3 23  ? 168.577 160.999 172.688 1.00 86.20  ? 23  LEU A O   1 
ATOM   4259 C CB  . LEU C 3 23  ? 167.157 162.986 174.908 1.00 76.75  ? 23  LEU A CB  1 
ATOM   4260 C CG  . LEU C 3 23  ? 167.000 162.569 176.365 1.00 81.09  ? 23  LEU A CG  1 
ATOM   4261 C CD1 . LEU C 3 23  ? 167.913 163.380 177.267 1.00 85.25  ? 23  LEU A CD1 1 
ATOM   4262 C CD2 . LEU C 3 23  ? 165.559 162.742 176.772 1.00 81.22  ? 23  LEU A CD2 1 
ATOM   4263 N N   . ARG C 3 24  ? 168.046 163.038 171.893 1.00 88.05  ? 24  ARG A N   1 
ATOM   4264 C CA  . ARG C 3 24  ? 167.898 162.537 170.531 1.00 87.70  ? 24  ARG A CA  1 
ATOM   4265 C C   . ARG C 3 24  ? 169.227 162.035 169.983 1.00 85.03  ? 24  ARG A C   1 
ATOM   4266 O O   . ARG C 3 24  ? 169.276 161.001 169.305 1.00 87.41  ? 24  ARG A O   1 
ATOM   4267 C CB  . ARG C 3 24  ? 167.317 163.624 169.628 1.00 89.77  ? 24  ARG A CB  1 
ATOM   4268 C CG  . ARG C 3 24  ? 166.447 163.089 168.505 1.00 89.69  ? 24  ARG A CG  1 
ATOM   4269 C CD  . ARG C 3 24  ? 166.229 164.130 167.419 1.00 89.35  ? 24  ARG A CD  1 
ATOM   4270 N N   . GLU C 3 25  ? 170.317 162.753 170.265 1.00 85.76  ? 25  GLU A N   1 
ATOM   4271 C CA  . GLU C 3 25  ? 171.627 162.288 169.818 1.00 85.53  ? 25  GLU A CA  1 
ATOM   4272 C C   . GLU C 3 25  ? 171.986 160.952 170.458 1.00 86.02  ? 25  GLU A C   1 
ATOM   4273 O O   . GLU C 3 25  ? 172.489 160.045 169.781 1.00 92.18  ? 25  GLU A O   1 
ATOM   4274 C CB  . GLU C 3 25  ? 172.694 163.337 170.129 1.00 89.27  ? 25  GLU A CB  1 
ATOM   4275 C CG  . GLU C 3 25  ? 174.114 162.872 169.861 1.00 88.84  ? 25  GLU A CG  1 
ATOM   4276 C CD  . GLU C 3 25  ? 175.010 163.990 169.369 1.00 95.05  ? 25  GLU A CD  1 
ATOM   4277 O OE1 . GLU C 3 25  ? 175.011 165.072 169.993 1.00 95.98  ? 25  GLU A OE1 1 
ATOM   4278 O OE2 . GLU C 3 25  ? 175.714 163.788 168.357 1.00 95.31  ? 25  GLU A OE2 1 
ATOM   4279 N N   . ASP C 3 26  ? 171.727 160.808 171.760 1.00 88.03  ? 26  ASP A N   1 
ATOM   4280 C CA  . ASP C 3 26  ? 172.026 159.548 172.432 1.00 89.45  ? 26  ASP A CA  1 
ATOM   4281 C C   . ASP C 3 26  ? 171.194 158.406 171.862 1.00 91.33  ? 26  ASP A C   1 
ATOM   4282 O O   . ASP C 3 26  ? 171.701 157.294 171.668 1.00 91.50  ? 26  ASP A O   1 
ATOM   4283 C CB  . ASP C 3 26  ? 171.793 159.685 173.936 1.00 90.41  ? 26  ASP A CB  1 
ATOM   4284 C CG  . ASP C 3 26  ? 172.180 158.436 174.700 1.00 94.51  ? 26  ASP A CG  1 
ATOM   4285 O OD1 . ASP C 3 26  ? 172.647 157.470 174.062 1.00 93.18  ? 26  ASP A OD1 1 
ATOM   4286 O OD2 . ASP C 3 26  ? 172.017 158.420 175.939 1.00 96.63  ? 26  ASP A OD2 1 
ATOM   4287 N N   . GLY C 3 27  ? 169.913 158.660 171.588 1.00 93.80  ? 27  GLY A N   1 
ATOM   4288 C CA  . GLY C 3 27  ? 169.074 157.625 171.008 1.00 93.09  ? 27  GLY A CA  1 
ATOM   4289 C C   . GLY C 3 27  ? 169.524 157.217 169.619 1.00 91.51  ? 27  GLY A C   1 
ATOM   4290 O O   . GLY C 3 27  ? 169.527 156.030 169.280 1.00 89.49  ? 27  GLY A O   1 
ATOM   4291 N N   . GLU C 3 28  ? 169.911 158.194 168.795 1.00 96.12  ? 28  GLU A N   1 
ATOM   4292 C CA  . GLU C 3 28  ? 170.419 157.875 167.465 1.00 95.53  ? 28  GLU A CA  1 
ATOM   4293 C C   . GLU C 3 28  ? 171.703 157.062 167.550 1.00 95.01  ? 28  GLU A C   1 
ATOM   4294 O O   . GLU C 3 28  ? 171.912 156.135 166.759 1.00 93.99  ? 28  GLU A O   1 
ATOM   4295 C CB  . GLU C 3 28  ? 170.645 159.156 166.664 1.00 97.54  ? 28  GLU A CB  1 
ATOM   4296 N N   . LYS C 3 29  ? 172.582 157.398 168.498 1.00 92.18  ? 29  LYS A N   1 
ATOM   4297 C CA  . LYS C 3 29  ? 173.799 156.612 168.678 1.00 88.65  ? 29  LYS A CA  1 
ATOM   4298 C C   . LYS C 3 29  ? 173.481 155.188 169.113 1.00 88.49  ? 29  LYS A C   1 
ATOM   4299 O O   . LYS C 3 29  ? 174.086 154.230 168.619 1.00 86.19  ? 29  LYS A O   1 
ATOM   4300 C CB  . LYS C 3 29  ? 174.719 157.283 169.696 1.00 88.99  ? 29  LYS A CB  1 
ATOM   4301 C CG  . LYS C 3 29  ? 176.054 156.579 169.866 1.00 88.14  ? 29  LYS A CG  1 
ATOM   4302 C CD  . LYS C 3 29  ? 176.895 157.239 170.944 1.00 89.46  ? 29  LYS A CD  1 
ATOM   4303 C CE  . LYS C 3 29  ? 176.782 156.493 172.263 1.00 91.84  ? 29  LYS A CE  1 
ATOM   4304 N NZ  . LYS C 3 29  ? 176.464 155.052 172.062 1.00 90.47  ? 29  LYS A NZ  1 
ATOM   4305 N N   . ALA C 3 30  ? 172.533 155.027 170.035 1.00 94.82  ? 30  ALA A N   1 
ATOM   4306 C CA  . ALA C 3 30  ? 172.200 153.709 170.558 1.00 92.40  ? 30  ALA A CA  1 
ATOM   4307 C C   . ALA C 3 30  ? 171.362 152.875 169.600 1.00 92.08  ? 30  ALA A C   1 
ATOM   4308 O O   . ALA C 3 30  ? 171.245 151.663 169.805 1.00 90.53  ? 30  ALA A O   1 
ATOM   4309 C CB  . ALA C 3 30  ? 171.464 153.845 171.893 1.00 94.40  ? 30  ALA A CB  1 
ATOM   4310 N N   . ALA C 3 31  ? 170.773 153.485 168.569 1.00 98.22  ? 31  ALA A N   1 
ATOM   4311 C CA  . ALA C 3 31  ? 169.951 152.718 167.637 1.00 97.50  ? 31  ALA A CA  1 
ATOM   4312 C C   . ALA C 3 31  ? 170.793 151.819 166.740 1.00 98.09  ? 31  ALA A C   1 
ATOM   4313 O O   . ALA C 3 31  ? 170.303 150.786 166.270 1.00 94.64  ? 31  ALA A O   1 
ATOM   4314 C CB  . ALA C 3 31  ? 169.098 153.661 166.790 1.00 98.12  ? 31  ALA A CB  1 
ATOM   4315 N N   . ARG C 3 32  ? 172.046 152.187 166.488 1.00 101.63 ? 32  ARG A N   1 
ATOM   4316 C CA  . ARG C 3 32  ? 172.925 151.412 165.612 1.00 95.89  ? 32  ARG A CA  1 
ATOM   4317 C C   . ARG C 3 32  ? 173.732 150.378 166.391 1.00 97.46  ? 32  ARG A C   1 
ATOM   4318 O O   . ARG C 3 32  ? 174.957 150.321 166.300 1.00 97.56  ? 32  ARG A O   1 
ATOM   4319 C CB  . ARG C 3 32  ? 173.846 152.350 164.842 1.00 95.35  ? 32  ARG A CB  1 
ATOM   4320 C CG  . ARG C 3 32  ? 173.222 153.684 164.482 1.00 98.63  ? 32  ARG A CG  1 
ATOM   4321 C CD  . ARG C 3 32  ? 174.116 154.467 163.536 1.00 99.53  ? 32  ARG A CD  1 
ATOM   4322 N NE  . ARG C 3 32  ? 175.525 154.147 163.728 1.00 100.29 ? 32  ARG A NE  1 
ATOM   4323 C CZ  . ARG C 3 32  ? 176.345 154.821 164.523 1.00 100.86 ? 32  ARG A CZ  1 
ATOM   4324 N NH1 . ARG C 3 32  ? 175.930 155.870 165.215 1.00 100.28 ? 32  ARG A NH1 1 
ATOM   4325 N NH2 . ARG C 3 32  ? 177.613 154.435 164.625 1.00 101.94 ? 32  ARG A NH2 1 
ATOM   4326 N N   . GLU C 3 33  ? 173.042 149.542 167.162 1.00 99.14  ? 33  GLU A N   1 
ATOM   4327 C CA  . GLU C 3 33  ? 173.702 148.513 167.958 1.00 96.22  ? 33  GLU A CA  1 
ATOM   4328 C C   . GLU C 3 33  ? 172.768 147.320 168.073 1.00 99.09  ? 33  GLU A C   1 
ATOM   4329 O O   . GLU C 3 33  ? 171.654 147.452 168.588 1.00 101.36 ? 33  GLU A O   1 
ATOM   4330 C CB  . GLU C 3 33  ? 174.075 149.045 169.343 1.00 93.99  ? 33  GLU A CB  1 
ATOM   4331 C CG  . GLU C 3 33  ? 175.439 148.599 169.832 1.00 97.21  ? 33  GLU A CG  1 
ATOM   4332 N N   . VAL C 3 34  ? 173.220 146.169 167.599 1.00 79.89  ? 34  VAL A N   1 
ATOM   4333 C CA  . VAL C 3 34  ? 172.428 144.946 167.615 1.00 78.17  ? 34  VAL A CA  1 
ATOM   4334 C C   . VAL C 3 34  ? 172.660 144.215 168.928 1.00 74.85  ? 34  VAL A C   1 
ATOM   4335 O O   . VAL C 3 34  ? 173.748 144.267 169.511 1.00 79.09  ? 34  VAL A O   1 
ATOM   4336 C CB  . VAL C 3 34  ? 172.765 144.061 166.399 1.00 81.01  ? 34  VAL A CB  1 
ATOM   4337 C CG1 . VAL C 3 34  ? 172.199 144.676 165.130 1.00 81.36  ? 34  VAL A CG1 1 
ATOM   4338 C CG2 . VAL C 3 34  ? 174.261 143.908 166.276 1.00 77.57  ? 34  VAL A CG2 1 
ATOM   4339 N N   . LYS C 3 35  ? 171.628 143.522 169.399 1.00 75.09  ? 35  LYS A N   1 
ATOM   4340 C CA  . LYS C 3 35  ? 171.625 142.922 170.724 1.00 78.21  ? 35  LYS A CA  1 
ATOM   4341 C C   . LYS C 3 35  ? 171.471 141.409 170.642 1.00 82.11  ? 35  LYS A C   1 
ATOM   4342 O O   . LYS C 3 35  ? 170.619 140.888 169.907 1.00 86.00  ? 35  LYS A O   1 
ATOM   4343 C CB  . LYS C 3 35  ? 170.506 143.515 171.581 1.00 75.47  ? 35  LYS A CB  1 
ATOM   4344 C CG  . LYS C 3 35  ? 170.550 145.028 171.675 1.00 81.48  ? 35  LYS A CG  1 
ATOM   4345 C CD  . LYS C 3 35  ? 169.560 145.551 172.700 1.00 84.47  ? 35  LYS A CD  1 
ATOM   4346 C CE  . LYS C 3 35  ? 169.331 147.043 172.532 1.00 82.25  ? 35  LYS A CE  1 
ATOM   4347 N NZ  . LYS C 3 35  ? 169.068 147.407 171.112 1.00 79.54  ? 35  LYS A NZ  1 
ATOM   4348 N N   . LEU C 3 36  ? 172.300 140.710 171.412 1.00 63.31  ? 36  LEU A N   1 
ATOM   4349 C CA  . LEU C 3 36  ? 172.264 139.261 171.517 1.00 61.65  ? 36  LEU A CA  1 
ATOM   4350 C C   . LEU C 3 36  ? 172.010 138.877 172.966 1.00 66.58  ? 36  LEU A C   1 
ATOM   4351 O O   . LEU C 3 36  ? 172.679 139.386 173.871 1.00 70.16  ? 36  LEU A O   1 
ATOM   4352 C CB  . LEU C 3 36  ? 173.573 138.641 171.029 1.00 56.86  ? 36  LEU A CB  1 
ATOM   4353 C CG  . LEU C 3 36  ? 174.115 139.149 169.698 1.00 58.78  ? 36  LEU A CG  1 
ATOM   4354 C CD1 . LEU C 3 36  ? 175.521 138.632 169.473 1.00 67.63  ? 36  LEU A CD1 1 
ATOM   4355 C CD2 . LEU C 3 36  ? 173.205 138.730 168.565 1.00 66.13  ? 36  LEU A CD2 1 
ATOM   4356 N N   . LEU C 3 37  ? 171.049 137.985 173.184 1.00 59.67  ? 37  LEU A N   1 
ATOM   4357 C CA  . LEU C 3 37  ? 170.750 137.471 174.515 1.00 52.49  ? 37  LEU A CA  1 
ATOM   4358 C C   . LEU C 3 37  ? 171.301 136.055 174.633 1.00 58.53  ? 37  LEU A C   1 
ATOM   4359 O O   . LEU C 3 37  ? 170.928 135.177 173.852 1.00 72.49  ? 37  LEU A O   1 
ATOM   4360 C CB  . LEU C 3 37  ? 169.247 137.487 174.783 1.00 52.42  ? 37  LEU A CB  1 
ATOM   4361 C CG  . LEU C 3 37  ? 168.807 136.854 176.101 1.00 56.48  ? 37  LEU A CG  1 
ATOM   4362 C CD1 . LEU C 3 37  ? 169.403 137.600 177.280 1.00 61.63  ? 37  LEU A CD1 1 
ATOM   4363 C CD2 . LEU C 3 37  ? 167.297 136.825 176.195 1.00 64.27  ? 37  LEU A CD2 1 
ATOM   4364 N N   . LEU C 3 38  ? 172.170 135.833 175.613 1.00 56.74  ? 38  LEU A N   1 
ATOM   4365 C CA  . LEU C 3 38  ? 172.895 134.576 175.751 1.00 54.81  ? 38  LEU A CA  1 
ATOM   4366 C C   . LEU C 3 38  ? 172.261 133.713 176.833 1.00 64.05  ? 38  LEU A C   1 
ATOM   4367 O O   . LEU C 3 38  ? 172.046 134.178 177.957 1.00 72.25  ? 38  LEU A O   1 
ATOM   4368 C CB  . LEU C 3 38  ? 174.364 134.835 176.082 1.00 52.09  ? 38  LEU A CB  1 
ATOM   4369 C CG  . LEU C 3 38  ? 175.228 133.600 176.325 1.00 57.28  ? 38  LEU A CG  1 
ATOM   4370 C CD1 . LEU C 3 38  ? 175.302 132.749 175.071 1.00 66.53  ? 38  LEU A CD1 1 
ATOM   4371 C CD2 . LEU C 3 38  ? 176.614 134.008 176.775 1.00 64.20  ? 38  LEU A CD2 1 
ATOM   4372 N N   . LEU C 3 39  ? 171.962 132.461 176.490 1.00 67.49  ? 39  LEU A N   1 
ATOM   4373 C CA  . LEU C 3 39  ? 171.362 131.519 177.422 1.00 65.42  ? 39  LEU A CA  1 
ATOM   4374 C C   . LEU C 3 39  ? 172.053 130.170 177.292 1.00 69.41  ? 39  LEU A C   1 
ATOM   4375 O O   . LEU C 3 39  ? 172.477 129.771 176.203 1.00 73.45  ? 39  LEU A O   1 
ATOM   4376 C CB  . LEU C 3 39  ? 169.859 131.368 177.177 1.00 56.46  ? 39  LEU A CB  1 
ATOM   4377 C CG  . LEU C 3 39  ? 168.990 132.489 177.742 1.00 61.12  ? 39  LEU A CG  1 
ATOM   4378 C CD1 . LEU C 3 39  ? 167.730 132.635 176.923 1.00 65.77  ? 39  LEU A CD1 1 
ATOM   4379 C CD2 . LEU C 3 39  ? 168.657 132.223 179.198 1.00 64.68  ? 39  LEU A CD2 1 
ATOM   4380 N N   . GLY C 3 40  ? 172.161 129.471 178.418 1.00 88.70  ? 40  GLY A N   1 
ATOM   4381 C CA  . GLY C 3 40  ? 172.825 128.181 178.445 1.00 90.16  ? 40  GLY A CA  1 
ATOM   4382 C C   . GLY C 3 40  ? 172.441 127.408 179.685 1.00 92.47  ? 40  GLY A C   1 
ATOM   4383 O O   . GLY C 3 40  ? 171.805 127.931 180.603 1.00 93.15  ? 40  GLY A O   1 
ATOM   4384 N N   . ALA C 3 41  ? 172.842 126.136 179.699 1.00 107.54 ? 41  ALA A N   1 
ATOM   4385 C CA  . ALA C 3 41  ? 172.545 125.238 180.814 1.00 108.54 ? 41  ALA A CA  1 
ATOM   4386 C C   . ALA C 3 41  ? 173.598 125.425 181.908 1.00 110.13 ? 41  ALA A C   1 
ATOM   4387 O O   . ALA C 3 41  ? 174.428 124.558 182.186 1.00 110.49 ? 41  ALA A O   1 
ATOM   4388 C CB  . ALA C 3 41  ? 172.480 123.795 180.336 1.00 107.97 ? 41  ALA A CB  1 
ATOM   4389 N N   . GLY C 3 42  ? 173.538 126.592 182.543 1.00 119.03 ? 42  GLY A N   1 
ATOM   4390 C CA  . GLY C 3 42  ? 174.508 126.919 183.576 1.00 119.31 ? 42  GLY A CA  1 
ATOM   4391 C C   . GLY C 3 42  ? 175.913 126.957 183.010 1.00 120.09 ? 42  GLY A C   1 
ATOM   4392 O O   . GLY C 3 42  ? 176.176 127.581 181.976 1.00 119.61 ? 42  GLY A O   1 
ATOM   4393 N N   . GLU C 3 43  ? 176.836 126.282 183.695 1.00 127.63 ? 43  GLU A N   1 
ATOM   4394 C CA  . GLU C 3 43  ? 178.227 126.203 183.251 1.00 127.77 ? 43  GLU A CA  1 
ATOM   4395 C C   . GLU C 3 43  ? 178.365 125.016 182.302 1.00 126.72 ? 43  GLU A C   1 
ATOM   4396 O O   . GLU C 3 43  ? 178.848 123.940 182.658 1.00 123.92 ? 43  GLU A O   1 
ATOM   4397 C CB  . GLU C 3 43  ? 179.166 126.086 184.446 1.00 127.96 ? 43  GLU A CB  1 
ATOM   4398 N N   . SER C 3 44  ? 177.923 125.226 181.062 1.00 117.08 ? 44  SER A N   1 
ATOM   4399 C CA  . SER C 3 44  ? 178.020 124.209 180.024 1.00 115.55 ? 44  SER A CA  1 
ATOM   4400 C C   . SER C 3 44  ? 179.023 124.593 178.945 1.00 111.05 ? 44  SER A C   1 
ATOM   4401 O O   . SER C 3 44  ? 179.979 123.853 178.696 1.00 113.48 ? 44  SER A O   1 
ATOM   4402 C CB  . SER C 3 44  ? 176.639 123.959 179.403 1.00 113.44 ? 44  SER A CB  1 
ATOM   4403 O OG  . SER C 3 44  ? 175.827 123.178 180.262 1.00 117.64 ? 44  SER A OG  1 
ATOM   4404 N N   . GLY C 3 45  ? 178.831 125.735 178.292 1.00 86.05  ? 45  GLY A N   1 
ATOM   4405 C CA  . GLY C 3 45  ? 179.809 126.224 177.342 1.00 87.26  ? 45  GLY A CA  1 
ATOM   4406 C C   . GLY C 3 45  ? 179.886 127.734 177.284 1.00 90.46  ? 45  GLY A C   1 
ATOM   4407 O O   . GLY C 3 45  ? 180.599 128.291 176.445 1.00 93.23  ? 45  GLY A O   1 
ATOM   4408 N N   . LYS C 3 46  ? 179.160 128.406 178.179 1.00 92.37  ? 46  LYS A N   1 
ATOM   4409 C CA  . LYS C 3 46  ? 179.051 129.859 178.104 1.00 92.81  ? 46  LYS A CA  1 
ATOM   4410 C C   . LYS C 3 46  ? 180.398 130.534 178.324 1.00 95.00  ? 46  LYS A C   1 
ATOM   4411 O O   . LYS C 3 46  ? 180.713 131.536 177.671 1.00 97.45  ? 46  LYS A O   1 
ATOM   4412 C CB  . LYS C 3 46  ? 178.027 130.359 179.122 1.00 92.55  ? 46  LYS A CB  1 
ATOM   4413 C CG  . LYS C 3 46  ? 176.663 129.703 178.998 1.00 92.07  ? 46  LYS A CG  1 
ATOM   4414 C CD  . LYS C 3 46  ? 175.575 130.481 179.728 1.00 92.29  ? 46  LYS A CD  1 
ATOM   4415 C CE  . LYS C 3 46  ? 176.112 131.252 180.926 1.00 93.59  ? 46  LYS A CE  1 
ATOM   4416 N NZ  . LYS C 3 46  ? 176.619 130.351 182.001 1.00 97.91  ? 46  LYS A NZ  1 
ATOM   4417 N N   . SER C 3 47  ? 181.205 130.000 179.243 1.00 97.98  ? 47  SER A N   1 
ATOM   4418 C CA  . SER C 3 47  ? 182.478 130.633 179.569 1.00 100.36 ? 47  SER A CA  1 
ATOM   4419 C C   . SER C 3 47  ? 183.395 130.693 178.353 1.00 102.01 ? 47  SER A C   1 
ATOM   4420 O O   . SER C 3 47  ? 184.072 131.702 178.127 1.00 102.54 ? 47  SER A O   1 
ATOM   4421 C CB  . SER C 3 47  ? 183.153 129.887 180.718 1.00 102.04 ? 47  SER A CB  1 
ATOM   4422 O OG  . SER C 3 47  ? 182.314 129.852 181.859 1.00 103.61 ? 47  SER A OG  1 
ATOM   4423 N N   . THR C 3 48  ? 183.435 129.620 177.561 1.00 97.41  ? 48  THR A N   1 
ATOM   4424 C CA  . THR C 3 48  ? 184.250 129.630 176.350 1.00 98.57  ? 48  THR A CA  1 
ATOM   4425 C C   . THR C 3 48  ? 183.722 130.637 175.333 1.00 97.84  ? 48  THR A C   1 
ATOM   4426 O O   . THR C 3 48  ? 184.503 131.365 174.710 1.00 92.27  ? 48  THR A O   1 
ATOM   4427 C CB  . THR C 3 48  ? 184.304 128.228 175.744 1.00 98.91  ? 48  THR A CB  1 
ATOM   4428 O OG1 . THR C 3 48  ? 184.938 127.334 176.667 1.00 98.24  ? 48  THR A OG1 1 
ATOM   4429 C CG2 . THR C 3 48  ? 185.089 128.236 174.440 1.00 98.83  ? 48  THR A CG2 1 
ATOM   4430 N N   . ILE C 3 49  ? 182.399 130.698 175.159 1.00 101.08 ? 49  ILE A N   1 
ATOM   4431 C CA  . ILE C 3 49  ? 181.809 131.645 174.214 1.00 100.27 ? 49  ILE A CA  1 
ATOM   4432 C C   . ILE C 3 49  ? 182.082 133.081 174.642 1.00 101.45 ? 49  ILE A C   1 
ATOM   4433 O O   . ILE C 3 49  ? 182.137 133.989 173.804 1.00 103.29 ? 49  ILE A O   1 
ATOM   4434 C CB  . ILE C 3 49  ? 180.298 131.374 174.064 1.00 99.01  ? 49  ILE A CB  1 
ATOM   4435 C CG1 . ILE C 3 49  ? 180.049 129.894 173.770 1.00 98.69  ? 49  ILE A CG1 1 
ATOM   4436 C CG2 . ILE C 3 49  ? 179.701 132.227 172.957 1.00 98.80  ? 49  ILE A CG2 1 
ATOM   4437 C CD1 . ILE C 3 49  ? 180.681 129.411 172.483 1.00 98.17  ? 49  ILE A CD1 1 
ATOM   4438 N N   . VAL C 3 50  ? 182.250 133.317 175.943 1.00 102.97 ? 50  VAL A N   1 
ATOM   4439 C CA  . VAL C 3 50  ? 182.588 134.655 176.417 1.00 105.30 ? 50  VAL A CA  1 
ATOM   4440 C C   . VAL C 3 50  ? 184.092 134.917 176.386 1.00 106.94 ? 50  VAL A C   1 
ATOM   4441 O O   . VAL C 3 50  ? 184.508 136.081 176.291 1.00 108.21 ? 50  VAL A O   1 
ATOM   4442 C CB  . VAL C 3 50  ? 182.021 134.875 177.833 1.00 104.18 ? 50  VAL A CB  1 
ATOM   4443 C CG1 . VAL C 3 50  ? 182.325 136.279 178.341 1.00 105.01 ? 50  VAL A CG1 1 
ATOM   4444 C CG2 . VAL C 3 50  ? 180.523 134.642 177.840 1.00 102.95 ? 50  VAL A CG2 1 
ATOM   4445 N N   . LYS C 3 51  ? 184.918 133.867 176.419 1.00 109.34 ? 51  LYS A N   1 
ATOM   4446 C CA  . LYS C 3 51  ? 186.362 134.053 176.525 1.00 110.38 ? 51  LYS A CA  1 
ATOM   4447 C C   . LYS C 3 51  ? 186.938 134.806 175.331 1.00 113.21 ? 51  LYS A C   1 
ATOM   4448 O O   . LYS C 3 51  ? 187.776 135.696 175.509 1.00 112.68 ? 51  LYS A O   1 
ATOM   4449 C CB  . LYS C 3 51  ? 187.054 132.698 176.677 1.00 110.31 ? 51  LYS A CB  1 
ATOM   4450 C CG  . LYS C 3 51  ? 187.451 132.362 178.105 1.00 111.13 ? 51  LYS A CG  1 
ATOM   4451 C CD  . LYS C 3 51  ? 187.499 130.859 178.326 1.00 112.07 ? 51  LYS A CD  1 
ATOM   4452 C CE  . LYS C 3 51  ? 187.919 130.522 179.747 1.00 110.86 ? 51  LYS A CE  1 
ATOM   4453 N NZ  . LYS C 3 51  ? 187.177 131.332 180.752 1.00 111.80 ? 51  LYS A NZ  1 
ATOM   4454 N N   . GLN C 3 52  ? 186.511 134.471 174.118 1.00 105.13 ? 52  GLN A N   1 
ATOM   4455 C CA  . GLN C 3 52  ? 187.029 135.143 172.931 1.00 102.32 ? 52  GLN A CA  1 
ATOM   4456 C C   . GLN C 3 52  ? 186.325 136.478 172.702 1.00 96.93  ? 52  GLN A C   1 
ATOM   4457 O O   . GLN C 3 52  ? 186.958 137.473 172.353 1.00 91.89  ? 52  GLN A O   1 
ATOM   4458 C CB  . GLN C 3 52  ? 186.884 134.251 171.696 1.00 100.36 ? 52  GLN A CB  1 
ATOM   4459 C CG  . GLN C 3 52  ? 185.592 134.457 170.928 1.00 102.12 ? 52  GLN A CG  1 
ATOM   4460 C CD  . GLN C 3 52  ? 184.373 134.112 171.752 1.00 101.34 ? 52  GLN A CD  1 
ATOM   4461 O OE1 . GLN C 3 52  ? 184.376 133.135 172.499 1.00 99.67  ? 52  GLN A OE1 1 
ATOM   4462 N NE2 . GLN C 3 52  ? 183.325 134.920 171.631 1.00 95.02  ? 52  GLN A NE2 1 
ATOM   4463 N N   . THR C 3 182 ? 176.442 141.297 190.191 1.00 87.59  ? 182 THR A N   1 
ATOM   4464 C CA  . THR C 3 182 ? 175.799 140.178 190.867 1.00 86.39  ? 182 THR A CA  1 
ATOM   4465 C C   . THR C 3 182 ? 174.540 139.767 190.106 1.00 86.35  ? 182 THR A C   1 
ATOM   4466 O O   . THR C 3 182 ? 174.098 138.621 190.182 1.00 86.76  ? 182 THR A O   1 
ATOM   4467 C CB  . THR C 3 182 ? 175.446 140.530 192.327 1.00 87.12  ? 182 THR A CB  1 
ATOM   4468 O OG1 . THR C 3 182 ? 176.611 141.036 192.990 1.00 88.64  ? 182 THR A OG1 1 
ATOM   4469 C CG2 . THR C 3 182 ? 174.955 139.300 193.076 1.00 85.26  ? 182 THR A CG2 1 
ATOM   4470 N N   . GLY C 3 183 ? 173.977 140.709 189.354 1.00 80.69  ? 183 GLY A N   1 
ATOM   4471 C CA  . GLY C 3 183 ? 172.815 140.423 188.537 1.00 81.08  ? 183 GLY A CA  1 
ATOM   4472 C C   . GLY C 3 183 ? 173.196 139.922 187.160 1.00 80.96  ? 183 GLY A C   1 
ATOM   4473 O O   . GLY C 3 183 ? 173.924 138.933 187.037 1.00 82.59  ? 183 GLY A O   1 
ATOM   4474 N N   . ILE C 3 184 ? 172.717 140.591 186.118 1.00 66.46  ? 184 ILE A N   1 
ATOM   4475 C CA  . ILE C 3 184 ? 173.089 140.230 184.756 1.00 67.58  ? 184 ILE A CA  1 
ATOM   4476 C C   . ILE C 3 184 ? 174.437 140.855 184.427 1.00 67.29  ? 184 ILE A C   1 
ATOM   4477 O O   . ILE C 3 184 ? 174.841 141.859 185.023 1.00 70.25  ? 184 ILE A O   1 
ATOM   4478 C CB  . ILE C 3 184 ? 171.998 140.663 183.757 1.00 66.15  ? 184 ILE A CB  1 
ATOM   4479 C CG1 . ILE C 3 184 ? 172.237 142.093 183.281 1.00 63.63  ? 184 ILE A CG1 1 
ATOM   4480 C CG2 . ILE C 3 184 ? 170.622 140.541 184.388 1.00 69.16  ? 184 ILE A CG2 1 
ATOM   4481 C CD1 . ILE C 3 184 ? 171.459 142.447 182.040 1.00 68.14  ? 184 ILE A CD1 1 
ATOM   4482 N N   . VAL C 3 185 ? 175.154 140.254 183.480 1.00 67.15  ? 185 VAL A N   1 
ATOM   4483 C CA  . VAL C 3 185 ? 176.488 140.712 183.107 1.00 66.02  ? 185 VAL A CA  1 
ATOM   4484 C C   . VAL C 3 185 ? 176.511 141.003 181.612 1.00 69.07  ? 185 VAL A C   1 
ATOM   4485 O O   . VAL C 3 185 ? 176.003 140.212 180.808 1.00 77.32  ? 185 VAL A O   1 
ATOM   4486 C CB  . VAL C 3 185 ? 177.573 139.693 183.508 1.00 70.28  ? 185 VAL A CB  1 
ATOM   4487 C CG1 . VAL C 3 185 ? 177.252 138.315 182.973 1.00 73.26  ? 185 VAL A CG1 1 
ATOM   4488 C CG2 . VAL C 3 185 ? 178.943 140.150 183.028 1.00 72.51  ? 185 VAL A CG2 1 
ATOM   4489 N N   . GLU C 3 186 ? 177.086 142.144 181.243 1.00 72.21  ? 186 GLU A N   1 
ATOM   4490 C CA  . GLU C 3 186 ? 177.080 142.622 179.870 1.00 73.04  ? 186 GLU A CA  1 
ATOM   4491 C C   . GLU C 3 186 ? 178.478 142.570 179.268 1.00 75.05  ? 186 GLU A C   1 
ATOM   4492 O O   . GLU C 3 186 ? 179.482 142.763 179.960 1.00 78.52  ? 186 GLU A O   1 
ATOM   4493 C CB  . GLU C 3 186 ? 176.543 144.052 179.793 1.00 77.56  ? 186 GLU A CB  1 
ATOM   4494 C CG  . GLU C 3 186 ? 175.039 144.138 179.638 1.00 82.55  ? 186 GLU A CG  1 
ATOM   4495 N N   . THR C 3 187 ? 178.528 142.309 177.965 1.00 73.47  ? 187 THR A N   1 
ATOM   4496 C CA  . THR C 3 187 ? 179.767 142.296 177.202 1.00 75.41  ? 187 THR A CA  1 
ATOM   4497 C C   . THR C 3 187 ? 179.611 143.187 175.977 1.00 79.09  ? 187 THR A C   1 
ATOM   4498 O O   . THR C 3 187 ? 178.528 143.278 175.391 1.00 80.77  ? 187 THR A O   1 
ATOM   4499 C CB  . THR C 3 187 ? 180.153 140.877 176.779 1.00 78.19  ? 187 THR A CB  1 
ATOM   4500 O OG1 . THR C 3 187 ? 179.754 139.952 177.798 1.00 78.75  ? 187 THR A OG1 1 
ATOM   4501 C CG2 . THR C 3 187 ? 181.656 140.773 176.576 1.00 78.26  ? 187 THR A CG2 1 
ATOM   4502 N N   . HIS C 3 188 ? 180.709 143.831 175.585 1.00 88.44  ? 188 HIS A N   1 
ATOM   4503 C CA  . HIS C 3 188 ? 180.699 144.931 174.622 1.00 86.27  ? 188 HIS A CA  1 
ATOM   4504 C C   . HIS C 3 188 ? 181.773 144.743 173.555 1.00 87.79  ? 188 HIS A C   1 
ATOM   4505 O O   . HIS C 3 188 ? 182.548 145.653 173.258 1.00 91.32  ? 188 HIS A O   1 
ATOM   4506 C CB  . HIS C 3 188 ? 180.902 146.265 175.333 1.00 89.00  ? 188 HIS A CB  1 
ATOM   4507 C CG  . HIS C 3 188 ? 179.656 146.827 175.941 1.00 95.81  ? 188 HIS A CG  1 
ATOM   4508 N ND1 . HIS C 3 188 ? 179.387 146.752 177.290 1.00 96.37  ? 188 HIS A ND1 1 
ATOM   4509 C CD2 . HIS C 3 188 ? 178.613 147.488 175.386 1.00 96.33  ? 188 HIS A CD2 1 
ATOM   4510 C CE1 . HIS C 3 188 ? 178.227 147.334 177.539 1.00 94.71  ? 188 HIS A CE1 1 
ATOM   4511 N NE2 . HIS C 3 188 ? 177.737 147.788 176.400 1.00 96.72  ? 188 HIS A NE2 1 
ATOM   4512 N N   . PHE C 3 189 ? 181.841 143.557 172.959 1.00 90.20  ? 189 PHE A N   1 
ATOM   4513 C CA  . PHE C 3 189 ? 182.829 143.334 171.915 1.00 90.31  ? 189 PHE A CA  1 
ATOM   4514 C C   . PHE C 3 189 ? 182.349 143.907 170.583 1.00 92.19  ? 189 PHE A C   1 
ATOM   4515 O O   . PHE C 3 189 ? 181.152 144.077 170.342 1.00 95.42  ? 189 PHE A O   1 
ATOM   4516 C CB  . PHE C 3 189 ? 183.140 141.845 171.767 1.00 89.67  ? 189 PHE A CB  1 
ATOM   4517 C CG  . PHE C 3 189 ? 182.152 141.095 170.921 1.00 91.66  ? 189 PHE A CG  1 
ATOM   4518 C CD1 . PHE C 3 189 ? 180.935 140.698 171.442 1.00 91.58  ? 189 PHE A CD1 1 
ATOM   4519 C CD2 . PHE C 3 189 ? 182.450 140.770 169.609 1.00 93.84  ? 189 PHE A CD2 1 
ATOM   4520 C CE1 . PHE C 3 189 ? 180.031 140.001 170.670 1.00 90.20  ? 189 PHE A CE1 1 
ATOM   4521 C CE2 . PHE C 3 189 ? 181.547 140.074 168.832 1.00 93.42  ? 189 PHE A CE2 1 
ATOM   4522 C CZ  . PHE C 3 189 ? 180.337 139.689 169.364 1.00 91.54  ? 189 PHE A CZ  1 
ATOM   4523 N N   . THR C 3 190 ? 183.312 144.206 169.711 1.00 96.79  ? 190 THR A N   1 
ATOM   4524 C CA  . THR C 3 190 ? 183.046 144.763 168.392 1.00 95.37  ? 190 THR A CA  1 
ATOM   4525 C C   . THR C 3 190 ? 183.790 143.952 167.340 1.00 96.73  ? 190 THR A C   1 
ATOM   4526 O O   . THR C 3 190 ? 184.812 143.322 167.623 1.00 101.50 ? 190 THR A O   1 
ATOM   4527 C CB  . THR C 3 190 ? 183.472 146.237 168.290 1.00 97.06  ? 190 THR A CB  1 
ATOM   4528 O OG1 . THR C 3 190 ? 184.887 146.312 168.080 1.00 97.27  ? 190 THR A OG1 1 
ATOM   4529 C CG2 . THR C 3 190 ? 183.115 146.995 169.560 1.00 96.64  ? 190 THR A CG2 1 
ATOM   4530 N N   . PHE C 3 191 ? 183.269 143.976 166.113 1.00 97.01  ? 191 PHE A N   1 
ATOM   4531 C CA  . PHE C 3 191 ? 183.877 143.222 165.024 1.00 98.97  ? 191 PHE A CA  1 
ATOM   4532 C C   . PHE C 3 191 ? 183.395 143.765 163.687 1.00 102.19 ? 191 PHE A C   1 
ATOM   4533 O O   . PHE C 3 191 ? 182.187 143.797 163.431 1.00 104.66 ? 191 PHE A O   1 
ATOM   4534 C CB  . PHE C 3 191 ? 183.545 141.731 165.137 1.00 97.42  ? 191 PHE A CB  1 
ATOM   4535 C CG  . PHE C 3 191 ? 184.212 140.881 164.096 1.00 97.93  ? 191 PHE A CG  1 
ATOM   4536 C CD1 . PHE C 3 191 ? 185.590 140.861 163.979 1.00 98.35  ? 191 PHE A CD1 1 
ATOM   4537 C CD2 . PHE C 3 191 ? 183.461 140.098 163.237 1.00 98.32  ? 191 PHE A CD2 1 
ATOM   4538 C CE1 . PHE C 3 191 ? 186.206 140.078 163.024 1.00 99.63  ? 191 PHE A CE1 1 
ATOM   4539 C CE2 . PHE C 3 191 ? 184.071 139.313 162.282 1.00 97.68  ? 191 PHE A CE2 1 
ATOM   4540 C CZ  . PHE C 3 191 ? 185.445 139.303 162.174 1.00 97.25  ? 191 PHE A CZ  1 
ATOM   4541 N N   . LYS C 3 192 ? 184.342 144.183 162.845 1.00 94.36  ? 192 LYS A N   1 
ATOM   4542 C CA  . LYS C 3 192 ? 184.083 144.565 161.455 1.00 87.83  ? 192 LYS A CA  1 
ATOM   4543 C C   . LYS C 3 192 ? 183.047 145.687 161.360 1.00 89.82  ? 192 LYS A C   1 
ATOM   4544 O O   . LYS C 3 192 ? 181.991 145.546 160.740 1.00 90.43  ? 192 LYS A O   1 
ATOM   4545 C CB  . LYS C 3 192 ? 183.654 143.348 160.631 1.00 87.75  ? 192 LYS A CB  1 
ATOM   4546 C CG  . LYS C 3 192 ? 184.795 142.414 160.267 1.00 92.54  ? 192 LYS A CG  1 
ATOM   4547 C CD  . LYS C 3 192 ? 184.975 142.323 158.762 1.00 94.09  ? 192 LYS A CD  1 
ATOM   4548 C CE  . LYS C 3 192 ? 185.918 141.193 158.388 1.00 92.57  ? 192 LYS A CE  1 
ATOM   4549 N NZ  . LYS C 3 192 ? 185.794 140.818 156.953 1.00 90.72  ? 192 LYS A NZ  1 
ATOM   4550 N N   . ASP C 3 193 ? 183.376 146.814 161.993 1.00 96.64  ? 193 ASP A N   1 
ATOM   4551 C CA  . ASP C 3 193 ? 182.564 148.031 161.929 1.00 98.18  ? 193 ASP A CA  1 
ATOM   4552 C C   . ASP C 3 193 ? 181.136 147.786 162.414 1.00 96.54  ? 193 ASP A C   1 
ATOM   4553 O O   . ASP C 3 193 ? 180.176 148.353 161.889 1.00 97.62  ? 193 ASP A O   1 
ATOM   4554 C CB  . ASP C 3 193 ? 182.563 148.619 160.516 1.00 101.40 ? 193 ASP A CB  1 
ATOM   4555 C CG  . ASP C 3 193 ? 183.954 148.708 159.921 1.00 103.55 ? 193 ASP A CG  1 
ATOM   4556 O OD1 . ASP C 3 193 ? 184.900 149.041 160.666 1.00 104.22 ? 193 ASP A OD1 1 
ATOM   4557 O OD2 . ASP C 3 193 ? 184.102 148.444 158.709 1.00 103.22 ? 193 ASP A OD2 1 
ATOM   4558 N N   . LEU C 3 194 ? 180.994 146.932 163.423 1.00 82.42  ? 194 LEU A N   1 
ATOM   4559 C CA  . LEU C 3 194 ? 179.707 146.679 164.050 1.00 78.87  ? 194 LEU A CA  1 
ATOM   4560 C C   . LEU C 3 194 ? 179.911 146.515 165.547 1.00 86.14  ? 194 LEU A C   1 
ATOM   4561 O O   . LEU C 3 194 ? 180.851 145.845 165.982 1.00 87.99  ? 194 LEU A O   1 
ATOM   4562 C CB  . LEU C 3 194 ? 179.032 145.433 163.472 1.00 79.65  ? 194 LEU A CB  1 
ATOM   4563 C CG  . LEU C 3 194 ? 177.829 145.684 162.566 1.00 81.42  ? 194 LEU A CG  1 
ATOM   4564 C CD1 . LEU C 3 194 ? 177.211 144.369 162.127 1.00 84.98  ? 194 LEU A CD1 1 
ATOM   4565 C CD2 . LEU C 3 194 ? 176.803 146.550 163.273 1.00 82.16  ? 194 LEU A CD2 1 
ATOM   4566 N N   . HIS C 3 195 ? 179.026 147.125 166.328 1.00 96.04  ? 195 HIS A N   1 
ATOM   4567 C CA  . HIS C 3 195 ? 179.111 147.094 167.781 1.00 93.81  ? 195 HIS A CA  1 
ATOM   4568 C C   . HIS C 3 195 ? 178.095 146.093 168.314 1.00 94.34  ? 195 HIS A C   1 
ATOM   4569 O O   . HIS C 3 195 ? 176.901 146.191 168.012 1.00 96.59  ? 195 HIS A O   1 
ATOM   4570 C CB  . HIS C 3 195 ? 178.865 148.483 168.368 1.00 92.78  ? 195 HIS A CB  1 
ATOM   4571 C CG  . HIS C 3 195 ? 179.914 149.486 168.002 1.00 95.97  ? 195 HIS A CG  1 
ATOM   4572 N ND1 . HIS C 3 195 ? 181.249 149.162 167.896 1.00 95.41  ? 195 HIS A ND1 1 
ATOM   4573 C CD2 . HIS C 3 195 ? 179.824 150.806 167.714 1.00 97.31  ? 195 HIS A CD2 1 
ATOM   4574 C CE1 . HIS C 3 195 ? 181.936 150.238 167.560 1.00 97.00  ? 195 HIS A CE1 1 
ATOM   4575 N NE2 . HIS C 3 195 ? 181.095 151.250 167.443 1.00 98.31  ? 195 HIS A NE2 1 
ATOM   4576 N N   . PHE C 3 196 ? 178.571 145.138 169.106 1.00 85.17  ? 196 PHE A N   1 
ATOM   4577 C CA  . PHE C 3 196 ? 177.750 144.062 169.637 1.00 83.11  ? 196 PHE A CA  1 
ATOM   4578 C C   . PHE C 3 196 ? 177.575 144.236 171.138 1.00 82.93  ? 196 PHE A C   1 
ATOM   4579 O O   . PHE C 3 196 ? 178.513 144.625 171.841 1.00 88.39  ? 196 PHE A O   1 
ATOM   4580 C CB  . PHE C 3 196 ? 178.384 142.700 169.350 1.00 83.08  ? 196 PHE A CB  1 
ATOM   4581 C CG  . PHE C 3 196 ? 178.110 142.173 167.972 1.00 87.18  ? 196 PHE A CG  1 
ATOM   4582 C CD1 . PHE C 3 196 ? 176.822 141.883 167.566 1.00 87.03  ? 196 PHE A CD1 1 
ATOM   4583 C CD2 . PHE C 3 196 ? 179.149 141.955 167.085 1.00 88.56  ? 196 PHE A CD2 1 
ATOM   4584 C CE1 . PHE C 3 196 ? 176.577 141.392 166.300 1.00 86.48  ? 196 PHE A CE1 1 
ATOM   4585 C CE2 . PHE C 3 196 ? 178.908 141.465 165.820 1.00 87.09  ? 196 PHE A CE2 1 
ATOM   4586 C CZ  . PHE C 3 196 ? 177.620 141.185 165.428 1.00 86.27  ? 196 PHE A CZ  1 
ATOM   4587 N N   . LYS C 3 197 ? 176.373 143.947 171.625 1.00 81.00  ? 197 LYS A N   1 
ATOM   4588 C CA  . LYS C 3 197 ? 176.057 144.009 173.046 1.00 82.06  ? 197 LYS A CA  1 
ATOM   4589 C C   . LYS C 3 197 ? 175.455 142.674 173.458 1.00 85.78  ? 197 LYS A C   1 
ATOM   4590 O O   . LYS C 3 197 ? 174.439 142.250 172.896 1.00 92.53  ? 197 LYS A O   1 
ATOM   4591 C CB  . LYS C 3 197 ? 175.093 145.161 173.338 1.00 89.06  ? 197 LYS A CB  1 
ATOM   4592 N N   . MET C 3 198 ? 176.075 142.016 174.434 1.00 77.80  ? 198 MET A N   1 
ATOM   4593 C CA  . MET C 3 198 ? 175.678 140.680 174.859 1.00 75.47  ? 198 MET A CA  1 
ATOM   4594 C C   . MET C 3 198 ? 175.245 140.706 176.316 1.00 77.07  ? 198 MET A C   1 
ATOM   4595 O O   . MET C 3 198 ? 175.948 141.265 177.164 1.00 86.12  ? 198 MET A O   1 
ATOM   4596 C CB  . MET C 3 198 ? 176.823 139.682 174.677 1.00 74.03  ? 198 MET A CB  1 
ATOM   4597 C CG  . MET C 3 198 ? 176.368 138.272 174.364 1.00 75.63  ? 198 MET A CG  1 
ATOM   4598 S SD  . MET C 3 198 ? 177.738 137.107 174.309 1.00 83.97  ? 198 MET A SD  1 
ATOM   4599 C CE  . MET C 3 198 ? 178.687 137.776 172.952 1.00 76.76  ? 198 MET A CE  1 
ATOM   4600 N N   . PHE C 3 199 ? 174.099 140.097 176.602 1.00 70.09  ? 199 PHE A N   1 
ATOM   4601 C CA  . PHE C 3 199 ? 173.582 139.969 177.957 1.00 73.28  ? 199 PHE A CA  1 
ATOM   4602 C C   . PHE C 3 199 ? 173.675 138.516 178.397 1.00 74.36  ? 199 PHE A C   1 
ATOM   4603 O O   . PHE C 3 199 ? 173.264 137.615 177.658 1.00 80.96  ? 199 PHE A O   1 
ATOM   4604 C CB  . PHE C 3 199 ? 172.128 140.439 178.044 1.00 75.75  ? 199 PHE A CB  1 
ATOM   4605 C CG  . PHE C 3 199 ? 171.854 141.714 177.309 1.00 75.81  ? 199 PHE A CG  1 
ATOM   4606 C CD1 . PHE C 3 199 ? 172.598 142.848 177.562 1.00 75.43  ? 199 PHE A CD1 1 
ATOM   4607 C CD2 . PHE C 3 199 ? 170.838 141.781 176.374 1.00 78.83  ? 199 PHE A CD2 1 
ATOM   4608 C CE1 . PHE C 3 199 ? 172.343 144.022 176.891 1.00 77.26  ? 199 PHE A CE1 1 
ATOM   4609 C CE2 . PHE C 3 199 ? 170.578 142.952 175.698 1.00 81.36  ? 199 PHE A CE2 1 
ATOM   4610 C CZ  . PHE C 3 199 ? 171.332 144.074 175.956 1.00 81.26  ? 199 PHE A CZ  1 
ATOM   4611 N N   . ASP C 3 200 ? 174.211 138.288 179.593 1.00 76.87  ? 200 ASP A N   1 
ATOM   4612 C CA  . ASP C 3 200 ? 174.221 136.970 180.211 1.00 76.91  ? 200 ASP A CA  1 
ATOM   4613 C C   . ASP C 3 200 ? 173.403 137.095 181.487 1.00 76.74  ? 200 ASP A C   1 
ATOM   4614 O O   . ASP C 3 200 ? 173.699 137.943 182.339 1.00 80.66  ? 200 ASP A O   1 
ATOM   4615 C CB  . ASP C 3 200 ? 175.660 136.501 180.475 1.00 79.87  ? 200 ASP A CB  1 
ATOM   4616 C CG  . ASP C 3 200 ? 175.758 135.260 181.375 1.00 85.63  ? 200 ASP A CG  1 
ATOM   4617 O OD1 . ASP C 3 200 ? 174.798 134.887 182.081 1.00 88.03  ? 200 ASP A OD1 1 
ATOM   4618 O OD2 . ASP C 3 200 ? 176.841 134.640 181.371 1.00 84.77  ? 200 ASP A OD2 1 
ATOM   4619 N N   . VAL C 3 201 ? 172.378 136.255 181.608 1.00 66.32  ? 201 VAL A N   1 
ATOM   4620 C CA  . VAL C 3 201 ? 171.397 136.324 182.680 1.00 67.33  ? 201 VAL A CA  1 
ATOM   4621 C C   . VAL C 3 201 ? 171.291 134.990 183.423 1.00 72.83  ? 201 VAL A C   1 
ATOM   4622 O O   . VAL C 3 201 ? 170.303 134.722 184.100 1.00 76.57  ? 201 VAL A O   1 
ATOM   4623 C CB  . VAL C 3 201 ? 170.033 136.792 182.129 1.00 73.25  ? 201 VAL A CB  1 
ATOM   4624 C CG1 . VAL C 3 201 ? 169.329 135.669 181.373 1.00 75.50  ? 201 VAL A CG1 1 
ATOM   4625 C CG2 . VAL C 3 201 ? 169.153 137.377 183.235 1.00 74.92  ? 201 VAL A CG2 1 
ATOM   4626 N N   . GLY C 3 202 ? 172.329 134.157 183.329 1.00 84.36  ? 202 GLY A N   1 
ATOM   4627 C CA  . GLY C 3 202 ? 172.304 132.861 183.985 1.00 86.83  ? 202 GLY A CA  1 
ATOM   4628 C C   . GLY C 3 202 ? 172.352 132.927 185.496 1.00 86.35  ? 202 GLY A C   1 
ATOM   4629 O O   . GLY C 3 202 ? 172.065 131.924 186.158 1.00 85.22  ? 202 GLY A O   1 
ATOM   4630 N N   . ALA C 3 203 ? 172.707 134.078 186.056 1.00 85.89  ? 203 ALA A N   1 
ATOM   4631 C CA  . ALA C 3 203 ? 172.784 134.263 187.488 1.00 83.54  ? 203 ALA A CA  1 
ATOM   4632 C C   . ALA C 3 203 ? 171.525 134.780 188.147 1.00 85.48  ? 203 ALA A C   1 
ATOM   4633 O O   . ALA C 3 203 ? 171.579 135.197 189.308 1.00 85.16  ? 203 ALA A O   1 
ATOM   4634 C CB  . ALA C 3 203 ? 173.940 135.198 187.810 1.00 50.00  ? 203 ALA A CB  1 
ATOM   4635 N N   . GLN C 3 204 ? 170.390 134.770 187.446 1.00 88.93  ? 204 GLN A N   1 
ATOM   4636 C CA  . GLN C 3 204 ? 169.161 135.310 188.017 1.00 89.97  ? 204 GLN A CA  1 
ATOM   4637 C C   . GLN C 3 204 ? 168.579 134.367 189.063 1.00 92.14  ? 204 GLN A C   1 
ATOM   4638 O O   . GLN C 3 204 ? 168.391 134.747 190.224 1.00 92.57  ? 204 GLN A O   1 
ATOM   4639 C CB  . GLN C 3 204 ? 168.147 135.583 186.906 1.00 88.10  ? 204 GLN A CB  1 
ATOM   4640 C CG  . GLN C 3 204 ? 167.281 136.808 187.145 1.00 90.74  ? 204 GLN A CG  1 
ATOM   4641 C CD  . GLN C 3 204 ? 168.078 137.995 187.643 1.00 91.74  ? 204 GLN A CD  1 
ATOM   4642 O OE1 . GLN C 3 204 ? 167.902 138.446 188.774 1.00 92.45  ? 204 GLN A OE1 1 
ATOM   4643 N NE2 . GLN C 3 204 ? 168.963 138.510 186.798 1.00 89.12  ? 204 GLN A NE2 1 
ATOM   4644 N N   . ARG C 3 205 ? 168.284 133.128 188.663 1.00 100.50 ? 205 ARG A N   1 
ATOM   4645 C CA  . ARG C 3 205 ? 167.747 132.102 189.560 1.00 98.81  ? 205 ARG A CA  1 
ATOM   4646 C C   . ARG C 3 205 ? 166.436 132.553 190.205 1.00 102.31 ? 205 ARG A C   1 
ATOM   4647 O O   . ARG C 3 205 ? 166.250 132.468 191.420 1.00 101.47 ? 205 ARG A O   1 
ATOM   4648 C CB  . ARG C 3 205 ? 168.775 131.707 190.624 1.00 99.68  ? 205 ARG A CB  1 
ATOM   4649 C CG  . ARG C 3 205 ? 170.043 131.088 190.059 1.00 102.64 ? 205 ARG A CG  1 
ATOM   4650 N N   . SER C 3 206 ? 165.519 133.037 189.372 1.00 98.58  ? 206 SER A N   1 
ATOM   4651 C CA  . SER C 3 206 ? 164.193 133.445 189.817 1.00 95.55  ? 206 SER A CA  1 
ATOM   4652 C C   . SER C 3 206 ? 163.194 133.061 188.731 1.00 95.95  ? 206 SER A C   1 
ATOM   4653 O O   . SER C 3 206 ? 163.510 132.304 187.808 1.00 97.11  ? 206 SER A O   1 
ATOM   4654 C CB  . SER C 3 206 ? 164.159 134.944 190.140 1.00 92.06  ? 206 SER A CB  1 
ATOM   4655 O OG  . SER C 3 206 ? 164.403 135.718 188.979 1.00 90.35  ? 206 SER A OG  1 
ATOM   4656 N N   . GLU C 3 207 ? 161.976 133.587 188.838 1.00 98.90  ? 207 GLU A N   1 
ATOM   4657 C CA  . GLU C 3 207 ? 160.924 133.284 187.873 1.00 98.02  ? 207 GLU A CA  1 
ATOM   4658 C C   . GLU C 3 207 ? 161.198 134.060 186.591 1.00 95.41  ? 207 GLU A C   1 
ATOM   4659 O O   . GLU C 3 207 ? 161.113 135.293 186.572 1.00 97.51  ? 207 GLU A O   1 
ATOM   4660 C CB  . GLU C 3 207 ? 159.554 133.631 188.447 1.00 97.23  ? 207 GLU A CB  1 
ATOM   4661 C CG  . GLU C 3 207 ? 158.393 133.312 187.521 1.00 96.91  ? 207 GLU A CG  1 
ATOM   4662 C CD  . GLU C 3 207 ? 158.494 131.927 186.913 1.00 101.17 ? 207 GLU A CD  1 
ATOM   4663 O OE1 . GLU C 3 207 ? 158.709 130.957 187.669 1.00 101.45 ? 207 GLU A OE1 1 
ATOM   4664 O OE2 . GLU C 3 207 ? 158.360 131.808 185.677 1.00 101.07 ? 207 GLU A OE2 1 
ATOM   4665 N N   . ARG C 3 208 ? 161.525 133.341 185.517 1.00 84.57  ? 208 ARG A N   1 
ATOM   4666 C CA  . ARG C 3 208 ? 161.919 133.987 184.273 1.00 87.85  ? 208 ARG A CA  1 
ATOM   4667 C C   . ARG C 3 208 ? 160.739 134.555 183.499 1.00 86.07  ? 208 ARG A C   1 
ATOM   4668 O O   . ARG C 3 208 ? 160.945 135.387 182.609 1.00 89.57  ? 208 ARG A O   1 
ATOM   4669 C CB  . ARG C 3 208 ? 162.689 133.004 183.387 1.00 86.84  ? 208 ARG A CB  1 
ATOM   4670 C CG  . ARG C 3 208 ? 161.814 132.178 182.461 1.00 88.29  ? 208 ARG A CG  1 
ATOM   4671 C CD  . ARG C 3 208 ? 162.633 131.534 181.354 1.00 85.90  ? 208 ARG A CD  1 
ATOM   4672 N NE  . ARG C 3 208 ? 163.471 130.449 181.851 1.00 86.71  ? 208 ARG A NE  1 
ATOM   4673 C CZ  . ARG C 3 208 ? 164.772 130.555 182.081 1.00 89.65  ? 208 ARG A CZ  1 
ATOM   4674 N NH1 . ARG C 3 208 ? 165.421 131.688 181.871 1.00 89.82  ? 208 ARG A NH1 1 
ATOM   4675 N NH2 . ARG C 3 208 ? 165.438 129.498 182.535 1.00 91.09  ? 208 ARG A NH2 1 
ATOM   4676 N N   . LYS C 3 209 ? 159.514 134.135 183.812 1.00 81.34  ? 209 LYS A N   1 
ATOM   4677 C CA  . LYS C 3 209 ? 158.357 134.637 183.084 1.00 86.42  ? 209 LYS A CA  1 
ATOM   4678 C C   . LYS C 3 209 ? 157.987 136.060 183.473 1.00 86.95  ? 209 LYS A C   1 
ATOM   4679 O O   . LYS C 3 209 ? 157.216 136.700 182.750 1.00 88.45  ? 209 LYS A O   1 
ATOM   4680 C CB  . LYS C 3 209 ? 157.160 133.705 183.298 1.00 87.66  ? 209 LYS A CB  1 
ATOM   4681 C CG  . LYS C 3 209 ? 156.693 133.586 184.740 1.00 85.90  ? 209 LYS A CG  1 
ATOM   4682 C CD  . LYS C 3 209 ? 155.505 132.644 184.856 1.00 86.75  ? 209 LYS A CD  1 
ATOM   4683 C CE  . LYS C 3 209 ? 155.907 131.209 184.556 1.00 89.12  ? 209 LYS A CE  1 
ATOM   4684 N NZ  . LYS C 3 209 ? 154.752 130.275 184.666 1.00 90.51  ? 209 LYS A NZ  1 
ATOM   4685 N N   . LYS C 3 210 ? 158.523 136.575 184.577 1.00 77.26  ? 210 LYS A N   1 
ATOM   4686 C CA  . LYS C 3 210 ? 158.183 137.904 185.061 1.00 76.71  ? 210 LYS A CA  1 
ATOM   4687 C C   . LYS C 3 210 ? 159.173 138.977 184.629 1.00 73.17  ? 210 LYS A C   1 
ATOM   4688 O O   . LYS C 3 210 ? 158.978 140.147 184.969 1.00 79.52  ? 210 LYS A O   1 
ATOM   4689 C CB  . LYS C 3 210 ? 158.066 137.893 186.587 1.00 76.87  ? 210 LYS A CB  1 
ATOM   4690 C CG  . LYS C 3 210 ? 156.880 138.676 187.115 1.00 73.65  ? 210 LYS A CG  1 
ATOM   4691 C CD  . LYS C 3 210 ? 155.604 138.297 186.387 1.00 73.61  ? 210 LYS A CD  1 
ATOM   4692 C CE  . LYS C 3 210 ? 154.377 138.765 187.145 1.00 75.28  ? 210 LYS A CE  1 
ATOM   4693 N NZ  . LYS C 3 210 ? 153.139 138.105 186.651 1.00 80.05  ? 210 LYS A NZ  1 
ATOM   4694 N N   . TRP C 3 211 ? 160.227 138.618 183.898 1.00 62.05  ? 211 TRP A N   1 
ATOM   4695 C CA  . TRP C 3 211 ? 161.149 139.620 183.384 1.00 66.82  ? 211 TRP A CA  1 
ATOM   4696 C C   . TRP C 3 211 ? 161.626 139.350 181.965 1.00 75.08  ? 211 TRP A C   1 
ATOM   4697 O O   . TRP C 3 211 ? 162.472 140.102 181.471 1.00 76.90  ? 211 TRP A O   1 
ATOM   4698 C CB  . TRP C 3 211 ? 162.373 139.754 184.305 1.00 68.21  ? 211 TRP A CB  1 
ATOM   4699 C CG  . TRP C 3 211 ? 163.051 138.461 184.622 1.00 63.96  ? 211 TRP A CG  1 
ATOM   4700 C CD1 . TRP C 3 211 ? 162.901 137.718 185.753 1.00 73.32  ? 211 TRP A CD1 1 
ATOM   4701 C CD2 . TRP C 3 211 ? 164.008 137.770 183.811 1.00 60.72  ? 211 TRP A CD2 1 
ATOM   4702 N NE1 . TRP C 3 211 ? 163.694 136.600 185.693 1.00 73.65  ? 211 TRP A NE1 1 
ATOM   4703 C CE2 . TRP C 3 211 ? 164.385 136.609 184.511 1.00 67.91  ? 211 TRP A CE2 1 
ATOM   4704 C CE3 . TRP C 3 211 ? 164.577 138.015 182.560 1.00 67.11  ? 211 TRP A CE3 1 
ATOM   4705 C CZ2 . TRP C 3 211 ? 165.302 135.697 184.001 1.00 69.94  ? 211 TRP A CZ2 1 
ATOM   4706 C CZ3 . TRP C 3 211 ? 165.488 137.108 182.056 1.00 68.18  ? 211 TRP A CZ3 1 
ATOM   4707 C CH2 . TRP C 3 211 ? 165.842 135.964 182.775 1.00 68.41  ? 211 TRP A CH2 1 
ATOM   4708 N N   . ILE C 3 212 ? 161.123 138.312 181.295 1.00 82.24  ? 212 ILE A N   1 
ATOM   4709 C CA  . ILE C 3 212 ? 161.607 138.005 179.953 1.00 78.45  ? 212 ILE A CA  1 
ATOM   4710 C C   . ILE C 3 212 ? 161.141 139.051 178.948 1.00 79.27  ? 212 ILE A C   1 
ATOM   4711 O O   . ILE C 3 212 ? 161.830 139.316 177.954 1.00 83.35  ? 212 ILE A O   1 
ATOM   4712 C CB  . ILE C 3 212 ? 161.181 136.583 179.543 1.00 72.93  ? 212 ILE A CB  1 
ATOM   4713 C CG1 . ILE C 3 212 ? 162.054 136.077 178.394 1.00 76.10  ? 212 ILE A CG1 1 
ATOM   4714 C CG2 . ILE C 3 212 ? 159.706 136.535 179.172 1.00 76.51  ? 212 ILE A CG2 1 
ATOM   4715 C CD1 . ILE C 3 212 ? 163.486 135.818 178.787 1.00 73.98  ? 212 ILE A CD1 1 
ATOM   4716 N N   . HIS C 3 213 ? 159.992 139.683 179.195 1.00 66.81  ? 213 HIS A N   1 
ATOM   4717 C CA  . HIS C 3 213 ? 159.455 140.651 178.248 1.00 67.40  ? 213 HIS A CA  1 
ATOM   4718 C C   . HIS C 3 213 ? 160.334 141.884 178.101 1.00 71.43  ? 213 HIS A C   1 
ATOM   4719 O O   . HIS C 3 213 ? 160.132 142.656 177.158 1.00 77.32  ? 213 HIS A O   1 
ATOM   4720 C CB  . HIS C 3 213 ? 158.040 141.062 178.659 1.00 70.58  ? 213 HIS A CB  1 
ATOM   4721 C CG  . HIS C 3 213 ? 157.940 141.600 180.052 1.00 69.47  ? 213 HIS A CG  1 
ATOM   4722 N ND1 . HIS C 3 213 ? 158.609 142.731 180.465 1.00 74.18  ? 213 HIS A ND1 1 
ATOM   4723 C CD2 . HIS C 3 213 ? 157.235 141.168 181.124 1.00 74.75  ? 213 HIS A CD2 1 
ATOM   4724 C CE1 . HIS C 3 213 ? 158.327 142.968 181.733 1.00 78.49  ? 213 HIS A CE1 1 
ATOM   4725 N NE2 . HIS C 3 213 ? 157.495 142.035 182.157 1.00 78.53  ? 213 HIS A NE2 1 
ATOM   4726 N N   . CYS C 3 214 ? 161.295 142.089 179.003 1.00 71.55  ? 214 CYS A N   1 
ATOM   4727 C CA  . CYS C 3 214 ? 162.247 143.178 178.830 1.00 72.71  ? 214 CYS A CA  1 
ATOM   4728 C C   . CYS C 3 214 ? 163.104 142.979 177.588 1.00 75.60  ? 214 CYS A C   1 
ATOM   4729 O O   . CYS C 3 214 ? 163.604 143.954 177.017 1.00 81.15  ? 214 CYS A O   1 
ATOM   4730 C CB  . CYS C 3 214 ? 163.135 143.306 180.067 1.00 74.95  ? 214 CYS A CB  1 
ATOM   4731 S SG  . CYS C 3 214 ? 162.251 143.675 181.596 1.00 96.40  ? 214 CYS A SG  1 
ATOM   4732 N N   . PHE C 3 215 ? 163.287 141.732 177.157 1.00 65.44  ? 215 PHE A N   1 
ATOM   4733 C CA  . PHE C 3 215 ? 164.148 141.408 176.021 1.00 65.68  ? 215 PHE A CA  1 
ATOM   4734 C C   . PHE C 3 215 ? 163.351 141.170 174.746 1.00 69.03  ? 215 PHE A C   1 
ATOM   4735 O O   . PHE C 3 215 ? 163.699 140.301 173.944 1.00 72.86  ? 215 PHE A O   1 
ATOM   4736 C CB  . PHE C 3 215 ? 165.010 140.193 176.342 1.00 62.34  ? 215 PHE A CB  1 
ATOM   4737 C CG  . PHE C 3 215 ? 165.822 140.337 177.592 1.00 60.23  ? 215 PHE A CG  1 
ATOM   4738 C CD1 . PHE C 3 215 ? 166.965 141.111 177.604 1.00 63.50  ? 215 PHE A CD1 1 
ATOM   4739 C CD2 . PHE C 3 215 ? 165.451 139.685 178.751 1.00 65.24  ? 215 PHE A CD2 1 
ATOM   4740 C CE1 . PHE C 3 215 ? 167.716 141.239 178.749 1.00 67.72  ? 215 PHE A CE1 1 
ATOM   4741 C CE2 . PHE C 3 215 ? 166.200 139.810 179.899 1.00 66.42  ? 215 PHE A CE2 1 
ATOM   4742 C CZ  . PHE C 3 215 ? 167.334 140.588 179.897 1.00 68.38  ? 215 PHE A CZ  1 
ATOM   4743 N N   . GLU C 3 216 ? 162.270 141.921 174.536 1.00 71.51  ? 216 GLU A N   1 
ATOM   4744 C CA  . GLU C 3 216 ? 161.440 141.697 173.358 1.00 68.34  ? 216 GLU A CA  1 
ATOM   4745 C C   . GLU C 3 216 ? 162.115 142.185 172.082 1.00 71.72  ? 216 GLU A C   1 
ATOM   4746 O O   . GLU C 3 216 ? 161.827 141.671 170.996 1.00 75.68  ? 216 GLU A O   1 
ATOM   4747 C CB  . GLU C 3 216 ? 160.087 142.382 173.536 1.00 69.89  ? 216 GLU A CB  1 
ATOM   4748 C CG  . GLU C 3 216 ? 159.041 141.975 172.517 1.00 74.30  ? 216 GLU A CG  1 
ATOM   4749 C CD  . GLU C 3 216 ? 157.633 142.306 172.967 1.00 81.01  ? 216 GLU A CD  1 
ATOM   4750 O OE1 . GLU C 3 216 ? 157.478 143.201 173.823 1.00 84.70  ? 216 GLU A OE1 1 
ATOM   4751 O OE2 . GLU C 3 216 ? 156.682 141.673 172.463 1.00 81.08  ? 216 GLU A OE2 1 
ATOM   4752 N N   . GLY C 3 217 ? 163.013 143.160 172.187 1.00 68.89  ? 217 GLY A N   1 
ATOM   4753 C CA  . GLY C 3 217 ? 163.599 143.766 171.008 1.00 69.77  ? 217 GLY A CA  1 
ATOM   4754 C C   . GLY C 3 217 ? 165.006 143.319 170.666 1.00 71.46  ? 217 GLY A C   1 
ATOM   4755 O O   . GLY C 3 217 ? 165.705 144.006 169.917 1.00 73.83  ? 217 GLY A O   1 
ATOM   4756 N N   . VAL C 3 218 ? 165.440 142.178 171.203 1.00 68.44  ? 218 VAL A N   1 
ATOM   4757 C CA  . VAL C 3 218 ? 166.797 141.713 170.943 1.00 64.63  ? 218 VAL A CA  1 
ATOM   4758 C C   . VAL C 3 218 ? 166.926 141.282 169.489 1.00 68.90  ? 218 VAL A C   1 
ATOM   4759 O O   . VAL C 3 218 ? 165.982 140.761 168.880 1.00 73.45  ? 218 VAL A O   1 
ATOM   4760 C CB  . VAL C 3 218 ? 167.181 140.564 171.891 1.00 65.34  ? 218 VAL A CB  1 
ATOM   4761 C CG1 . VAL C 3 218 ? 167.512 141.103 173.272 1.00 69.50  ? 218 VAL A CG1 1 
ATOM   4762 C CG2 . VAL C 3 218 ? 166.067 139.536 171.957 1.00 69.67  ? 218 VAL A CG2 1 
ATOM   4763 N N   . THR C 3 219 ? 168.112 141.508 168.920 1.00 68.84  ? 219 THR A N   1 
ATOM   4764 C CA  . THR C 3 219 ? 168.360 141.076 167.549 1.00 63.51  ? 219 THR A CA  1 
ATOM   4765 C C   . THR C 3 219 ? 168.384 139.557 167.444 1.00 63.90  ? 219 THR A C   1 
ATOM   4766 O O   . THR C 3 219 ? 167.820 138.990 166.501 1.00 68.14  ? 219 THR A O   1 
ATOM   4767 C CB  . THR C 3 219 ? 169.669 141.669 167.031 1.00 63.84  ? 219 THR A CB  1 
ATOM   4768 O OG1 . THR C 3 219 ? 169.707 143.072 167.320 1.00 74.92  ? 219 THR A OG1 1 
ATOM   4769 C CG2 . THR C 3 219 ? 169.789 141.464 165.533 1.00 58.19  ? 219 THR A CG2 1 
ATOM   4770 N N   . ALA C 3 220 ? 169.022 138.875 168.395 1.00 61.12  ? 220 ALA A N   1 
ATOM   4771 C CA  . ALA C 3 220 ? 169.104 137.422 168.299 1.00 60.05  ? 220 ALA A CA  1 
ATOM   4772 C C   . ALA C 3 220 ? 169.304 136.807 169.679 1.00 60.69  ? 220 ALA A C   1 
ATOM   4773 O O   . ALA C 3 220 ? 169.653 137.486 170.649 1.00 70.75  ? 220 ALA A O   1 
ATOM   4774 C CB  . ALA C 3 220 ? 170.226 136.993 167.350 1.00 61.30  ? 220 ALA A CB  1 
ATOM   4775 N N   . ILE C 3 221 ? 169.075 135.497 169.744 1.00 45.78  ? 221 ILE A N   1 
ATOM   4776 C CA  . ILE C 3 221 ? 169.271 134.698 170.946 1.00 46.39  ? 221 ILE A CA  1 
ATOM   4777 C C   . ILE C 3 221 ? 170.330 133.645 170.656 1.00 54.72  ? 221 ILE A C   1 
ATOM   4778 O O   . ILE C 3 221 ? 170.237 132.924 169.656 1.00 69.30  ? 221 ILE A O   1 
ATOM   4779 C CB  . ILE C 3 221 ? 167.964 134.031 171.409 1.00 45.67  ? 221 ILE A CB  1 
ATOM   4780 C CG1 . ILE C 3 221 ? 166.874 135.075 171.630 1.00 53.33  ? 221 ILE A CG1 1 
ATOM   4781 C CG2 . ILE C 3 221 ? 168.201 133.223 172.670 1.00 49.55  ? 221 ILE A CG2 1 
ATOM   4782 C CD1 . ILE C 3 221 ? 165.750 134.596 172.514 1.00 57.67  ? 221 ILE A CD1 1 
ATOM   4783 N N   . ILE C 3 222 ? 171.330 133.558 171.527 1.00 52.47  ? 222 ILE A N   1 
ATOM   4784 C CA  . ILE C 3 222 ? 172.365 132.536 171.457 1.00 50.17  ? 222 ILE A CA  1 
ATOM   4785 C C   . ILE C 3 222 ? 172.053 131.478 172.501 1.00 56.25  ? 222 ILE A C   1 
ATOM   4786 O O   . ILE C 3 222 ? 171.803 131.802 173.669 1.00 65.70  ? 222 ILE A O   1 
ATOM   4787 C CB  . ILE C 3 222 ? 173.761 133.136 171.686 1.00 52.01  ? 222 ILE A CB  1 
ATOM   4788 C CG1 . ILE C 3 222 ? 174.089 134.160 170.602 1.00 56.82  ? 222 ILE A CG1 1 
ATOM   4789 C CG2 . ILE C 3 222 ? 174.809 132.043 171.718 1.00 55.04  ? 222 ILE A CG2 1 
ATOM   4790 C CD1 . ILE C 3 222 ? 175.499 134.683 170.672 1.00 54.97  ? 222 ILE A CD1 1 
ATOM   4791 N N   . PHE C 3 223 ? 172.039 130.218 172.079 1.00 60.70  ? 223 PHE A N   1 
ATOM   4792 C CA  . PHE C 3 223 ? 171.746 129.090 172.950 1.00 62.53  ? 223 PHE A CA  1 
ATOM   4793 C C   . PHE C 3 223 ? 172.958 128.173 172.992 1.00 71.30  ? 223 PHE A C   1 
ATOM   4794 O O   . PHE C 3 223 ? 173.449 127.741 171.944 1.00 80.98  ? 223 PHE A O   1 
ATOM   4795 C CB  . PHE C 3 223 ? 170.519 128.325 172.456 1.00 59.06  ? 223 PHE A CB  1 
ATOM   4796 C CG  . PHE C 3 223 ? 169.707 127.712 173.552 1.00 61.66  ? 223 PHE A CG  1 
ATOM   4797 C CD1 . PHE C 3 223 ? 170.113 126.538 174.154 1.00 62.27  ? 223 PHE A CD1 1 
ATOM   4798 C CD2 . PHE C 3 223 ? 168.532 128.304 173.974 1.00 67.92  ? 223 PHE A CD2 1 
ATOM   4799 C CE1 . PHE C 3 223 ? 169.368 125.967 175.161 1.00 67.09  ? 223 PHE A CE1 1 
ATOM   4800 C CE2 . PHE C 3 223 ? 167.781 127.738 174.982 1.00 71.76  ? 223 PHE A CE2 1 
ATOM   4801 C CZ  . PHE C 3 223 ? 168.200 126.567 175.575 1.00 71.23  ? 223 PHE A CZ  1 
ATOM   4802 N N   . CYS C 3 224 ? 173.437 127.879 174.196 1.00 80.32  ? 224 CYS A N   1 
ATOM   4803 C CA  . CYS C 3 224 ? 174.610 127.036 174.382 1.00 75.05  ? 224 CYS A CA  1 
ATOM   4804 C C   . CYS C 3 224 ? 174.173 125.689 174.940 1.00 82.85  ? 224 CYS A C   1 
ATOM   4805 O O   . CYS C 3 224 ? 173.552 125.626 176.006 1.00 91.24  ? 224 CYS A O   1 
ATOM   4806 C CB  . CYS C 3 224 ? 175.622 127.704 175.310 1.00 82.42  ? 224 CYS A CB  1 
ATOM   4807 S SG  . CYS C 3 224 ? 176.460 129.132 174.588 1.00 102.57 ? 224 CYS A SG  1 
ATOM   4808 N N   . VAL C 3 225 ? 174.495 124.620 174.217 1.00 74.33  ? 225 VAL A N   1 
ATOM   4809 C CA  . VAL C 3 225 ? 174.185 123.255 174.621 1.00 70.90  ? 225 VAL A CA  1 
ATOM   4810 C C   . VAL C 3 225 ? 175.448 122.421 174.485 1.00 70.37  ? 225 VAL A C   1 
ATOM   4811 O O   . VAL C 3 225 ? 176.152 122.508 173.474 1.00 78.65  ? 225 VAL A O   1 
ATOM   4812 C CB  . VAL C 3 225 ? 173.044 122.652 173.777 1.00 74.90  ? 225 VAL A CB  1 
ATOM   4813 C CG1 . VAL C 3 225 ? 172.834 121.192 174.133 1.00 75.35  ? 225 VAL A CG1 1 
ATOM   4814 C CG2 . VAL C 3 225 ? 171.762 123.439 173.972 1.00 80.77  ? 225 VAL A CG2 1 
ATOM   4815 N N   . ALA C 3 226 ? 175.736 121.614 175.501 1.00 85.15  ? 226 ALA A N   1 
ATOM   4816 C CA  . ALA C 3 226 ? 176.920 120.769 175.497 1.00 94.98  ? 226 ALA A CA  1 
ATOM   4817 C C   . ALA C 3 226 ? 176.579 119.405 174.912 1.00 96.98  ? 226 ALA A C   1 
ATOM   4818 O O   . ALA C 3 226 ? 175.615 118.762 175.340 1.00 94.82  ? 226 ALA A O   1 
ATOM   4819 C CB  . ALA C 3 226 ? 177.482 120.618 176.910 1.00 93.42  ? 226 ALA A CB  1 
ATOM   4820 N N   . LEU C 3 227 ? 177.368 118.971 173.927 1.00 95.98  ? 227 LEU A N   1 
ATOM   4821 C CA  . LEU C 3 227 ? 177.147 117.670 173.310 1.00 90.98  ? 227 LEU A CA  1 
ATOM   4822 C C   . LEU C 3 227 ? 177.580 116.517 174.204 1.00 89.74  ? 227 LEU A C   1 
ATOM   4823 O O   . LEU C 3 227 ? 177.143 115.383 173.984 1.00 94.37  ? 227 LEU A O   1 
ATOM   4824 C CB  . LEU C 3 227 ? 177.883 117.588 171.972 1.00 90.23  ? 227 LEU A CB  1 
ATOM   4825 C CG  . LEU C 3 227 ? 177.109 118.030 170.733 1.00 90.63  ? 227 LEU A CG  1 
ATOM   4826 C CD1 . LEU C 3 227 ? 177.983 117.951 169.498 1.00 89.22  ? 227 LEU A CD1 1 
ATOM   4827 C CD2 . LEU C 3 227 ? 175.879 117.168 170.567 1.00 92.59  ? 227 LEU A CD2 1 
ATOM   4828 N N   . SER C 3 228 ? 178.423 116.777 175.200 1.00 85.68  ? 228 SER A N   1 
ATOM   4829 C CA  . SER C 3 228 ? 178.806 115.762 176.171 1.00 86.28  ? 228 SER A CA  1 
ATOM   4830 C C   . SER C 3 228 ? 177.751 115.557 177.245 1.00 87.47  ? 228 SER A C   1 
ATOM   4831 O O   . SER C 3 228 ? 177.957 114.741 178.149 1.00 88.68  ? 228 SER A O   1 
ATOM   4832 C CB  . SER C 3 228 ? 180.139 116.130 176.824 1.00 86.52  ? 228 SER A CB  1 
ATOM   4833 O OG  . SER C 3 228 ? 179.985 117.226 177.707 1.00 88.01  ? 228 SER A OG  1 
ATOM   4834 N N   . ASP C 3 229 ? 176.634 116.282 177.171 1.00 104.06 ? 229 ASP A N   1 
ATOM   4835 C CA  . ASP C 3 229 ? 175.589 116.170 178.178 1.00 105.18 ? 229 ASP A CA  1 
ATOM   4836 C C   . ASP C 3 229 ? 174.904 114.812 178.182 1.00 106.31 ? 229 ASP A C   1 
ATOM   4837 O O   . ASP C 3 229 ? 174.261 114.477 179.182 1.00 110.09 ? 229 ASP A O   1 
ATOM   4838 C CB  . ASP C 3 229 ? 174.541 117.267 177.981 1.00 109.38 ? 229 ASP A CB  1 
ATOM   4839 C CG  . ASP C 3 229 ? 175.035 118.628 178.424 1.00 111.83 ? 229 ASP A CG  1 
ATOM   4840 O OD1 . ASP C 3 229 ? 175.932 118.683 179.292 1.00 110.63 ? 229 ASP A OD1 1 
ATOM   4841 O OD2 . ASP C 3 229 ? 174.524 119.644 177.908 1.00 111.57 ? 229 ASP A OD2 1 
ATOM   4842 N N   . TYR C 3 230 ? 175.003 114.031 177.108 1.00 95.53  ? 230 TYR A N   1 
ATOM   4843 C CA  . TYR C 3 230 ? 174.439 112.691 177.151 1.00 93.18  ? 230 TYR A CA  1 
ATOM   4844 C C   . TYR C 3 230 ? 175.287 111.836 178.083 1.00 99.03  ? 230 TYR A C   1 
ATOM   4845 O O   . TYR C 3 230 ? 176.496 112.037 178.192 1.00 100.75 ? 230 TYR A O   1 
ATOM   4846 C CB  . TYR C 3 230 ? 174.361 112.069 175.753 1.00 86.92  ? 230 TYR A CB  1 
ATOM   4847 C CG  . TYR C 3 230 ? 175.561 111.252 175.342 1.00 89.62  ? 230 TYR A CG  1 
ATOM   4848 C CD1 . TYR C 3 230 ? 175.648 109.897 175.619 1.00 92.64  ? 230 TYR A CD1 1 
ATOM   4849 C CD2 . TYR C 3 230 ? 176.604 111.843 174.650 1.00 96.51  ? 230 TYR A CD2 1 
ATOM   4850 C CE1 . TYR C 3 230 ? 176.747 109.164 175.227 1.00 94.39  ? 230 TYR A CE1 1 
ATOM   4851 C CE2 . TYR C 3 230 ? 177.703 111.122 174.258 1.00 97.32  ? 230 TYR A CE2 1 
ATOM   4852 C CZ  . TYR C 3 230 ? 177.771 109.784 174.547 1.00 94.80  ? 230 TYR A CZ  1 
ATOM   4853 O OH  . TYR C 3 230 ? 178.872 109.072 174.149 1.00 99.42  ? 230 TYR A OH  1 
ATOM   4854 N N   . ASP C 3 231 ? 174.640 110.883 178.745 1.00 109.19 ? 231 ASP A N   1 
ATOM   4855 C CA  . ASP C 3 231 ? 175.063 110.211 179.996 1.00 105.98 ? 231 ASP A CA  1 
ATOM   4856 C C   . ASP C 3 231 ? 175.283 111.343 181.008 1.00 105.01 ? 231 ASP A C   1 
ATOM   4857 O O   . ASP C 3 231 ? 174.587 112.366 180.923 1.00 108.36 ? 231 ASP A O   1 
ATOM   4858 C CB  . ASP C 3 231 ? 176.245 109.217 179.787 1.00 107.85 ? 231 ASP A CB  1 
ATOM   4859 C CG  . ASP C 3 231 ? 177.645 109.861 179.759 1.00 110.53 ? 231 ASP A CG  1 
ATOM   4860 O OD1 . ASP C 3 231 ? 177.822 111.070 180.000 1.00 112.08 ? 231 ASP A OD1 1 
ATOM   4861 O OD2 . ASP C 3 231 ? 178.605 109.114 179.477 1.00 109.23 ? 231 ASP A OD2 1 
ATOM   4862 N N   . LEU C 3 232 ? 176.216 111.213 181.953 1.00 107.22 ? 232 LEU A N   1 
ATOM   4863 C CA  . LEU C 3 232 ? 176.452 112.239 182.973 1.00 111.12 ? 232 LEU A CA  1 
ATOM   4864 C C   . LEU C 3 232 ? 175.138 112.679 183.616 1.00 109.23 ? 232 LEU A C   1 
ATOM   4865 O O   . LEU C 3 232 ? 174.909 113.859 183.893 1.00 109.49 ? 232 LEU A O   1 
ATOM   4866 C CB  . LEU C 3 232 ? 177.202 113.438 182.386 1.00 110.42 ? 232 LEU A CB  1 
ATOM   4867 C CG  . LEU C 3 232 ? 178.694 113.293 182.080 1.00 108.03 ? 232 LEU A CG  1 
ATOM   4868 C CD1 . LEU C 3 232 ? 179.371 114.653 182.077 1.00 105.00 ? 232 LEU A CD1 1 
ATOM   4869 C CD2 . LEU C 3 232 ? 179.370 112.361 183.074 1.00 109.71 ? 232 LEU A CD2 1 
ATOM   4870 N N   . VAL C 3 233 ? 174.269 111.708 183.852 1.00 126.48 ? 233 VAL A N   1 
ATOM   4871 C CA  . VAL C 3 233 ? 172.896 111.976 184.247 1.00 127.49 ? 233 VAL A CA  1 
ATOM   4872 C C   . VAL C 3 233 ? 172.862 112.518 185.670 1.00 128.43 ? 233 VAL A C   1 
ATOM   4873 O O   . VAL C 3 233 ? 173.837 112.438 186.422 1.00 128.76 ? 233 VAL A O   1 
ATOM   4874 C CB  . VAL C 3 233 ? 172.023 110.713 184.116 1.00 130.42 ? 233 VAL A CB  1 
ATOM   4875 C CG1 . VAL C 3 233 ? 171.746 110.410 182.651 1.00 127.73 ? 233 VAL A CG1 1 
ATOM   4876 C CG2 . VAL C 3 233 ? 172.703 109.531 184.791 1.00 129.77 ? 233 VAL A CG2 1 
ATOM   4877 N N   . LEU C 3 234 ? 171.693 113.046 186.049 1.00 144.93 ? 234 LEU A N   1 
ATOM   4878 C CA  . LEU C 3 234 ? 171.461 113.492 187.454 1.00 147.74 ? 234 LEU A CA  1 
ATOM   4879 C C   . LEU C 3 234 ? 172.385 114.636 187.873 1.00 147.69 ? 234 LEU A C   1 
ATOM   4880 O O   . LEU C 3 234 ? 172.699 114.716 189.076 1.00 149.82 ? 234 LEU A O   1 
ATOM   4881 C CB  . LEU C 3 234 ? 171.610 112.290 188.394 1.00 149.06 ? 234 LEU A CB  1 
ATOM   4882 C CG  . LEU C 3 234 ? 171.213 112.553 189.845 1.00 146.74 ? 234 LEU A CG  1 
ATOM   4883 C CD1 . LEU C 3 234 ? 170.619 111.307 190.481 1.00 146.12 ? 234 LEU A CD1 1 
ATOM   4884 C CD2 . LEU C 3 234 ? 172.402 113.051 190.652 1.00 145.66 ? 234 LEU A CD2 1 
ATOM   4885 N N   . ALA C 3 235 ? 172.797 115.490 186.941 1.00 136.23 ? 235 ALA A N   1 
ATOM   4886 C CA  . ALA C 3 235 ? 173.564 116.658 187.358 1.00 136.41 ? 235 ALA A CA  1 
ATOM   4887 C C   . ALA C 3 235 ? 172.716 117.567 188.233 1.00 136.52 ? 235 ALA A C   1 
ATOM   4888 O O   . ALA C 3 235 ? 173.179 118.062 189.268 1.00 133.60 ? 235 ALA A O   1 
ATOM   4889 C CB  . ALA C 3 235 ? 174.084 117.414 186.139 1.00 134.14 ? 235 ALA A CB  1 
ATOM   4890 N N   . GLU C 3 236 ? 171.471 117.796 187.830 1.00 151.50 ? 236 GLU A N   1 
ATOM   4891 C CA  . GLU C 3 236 ? 170.498 118.433 188.700 1.00 153.22 ? 236 GLU A CA  1 
ATOM   4892 C C   . GLU C 3 236 ? 170.143 117.489 189.845 1.00 153.56 ? 236 GLU A C   1 
ATOM   4893 O O   . GLU C 3 236 ? 170.395 116.282 189.782 1.00 152.00 ? 236 GLU A O   1 
ATOM   4894 C CB  . GLU C 3 236 ? 169.247 118.813 187.906 1.00 153.30 ? 236 GLU A CB  1 
ATOM   4895 C CG  . GLU C 3 236 ? 168.402 119.908 188.536 1.00 153.13 ? 236 GLU A CG  1 
ATOM   4896 N N   . ASP C 3 237 ? 169.564 118.053 190.908 1.00 161.32 ? 237 ASP A N   1 
ATOM   4897 C CA  . ASP C 3 237 ? 169.241 117.244 192.080 1.00 160.80 ? 237 ASP A CA  1 
ATOM   4898 C C   . ASP C 3 237 ? 168.269 116.124 191.730 1.00 161.11 ? 237 ASP A C   1 
ATOM   4899 O O   . ASP C 3 237 ? 168.423 114.990 192.197 1.00 158.75 ? 237 ASP A O   1 
ATOM   4900 C CB  . ASP C 3 237 ? 168.670 118.128 193.191 1.00 159.82 ? 237 ASP A CB  1 
ATOM   4901 C CG  . ASP C 3 237 ? 167.472 118.937 192.736 1.00 161.36 ? 237 ASP A CG  1 
ATOM   4902 O OD1 . ASP C 3 237 ? 167.486 119.424 191.587 1.00 160.82 ? 237 ASP A OD1 1 
ATOM   4903 O OD2 . ASP C 3 237 ? 166.517 119.085 193.528 1.00 160.94 ? 237 ASP A OD2 1 
ATOM   4904 N N   . GLU C 3 238 ? 167.268 116.418 190.905 1.00 160.52 ? 238 GLU A N   1 
ATOM   4905 C CA  . GLU C 3 238 ? 166.334 115.390 190.471 1.00 158.72 ? 238 GLU A CA  1 
ATOM   4906 C C   . GLU C 3 238 ? 166.991 114.477 189.440 1.00 158.16 ? 238 GLU A C   1 
ATOM   4907 O O   . GLU C 3 238 ? 167.978 114.838 188.795 1.00 156.93 ? 238 GLU A O   1 
ATOM   4908 C CB  . GLU C 3 238 ? 165.069 116.028 189.894 1.00 158.08 ? 238 GLU A CB  1 
ATOM   4909 C CG  . GLU C 3 238 ? 165.326 117.227 188.997 1.00 158.29 ? 238 GLU A CG  1 
ATOM   4910 N N   . GLU C 3 239 ? 166.430 113.276 189.292 1.00 154.00 ? 239 GLU A N   1 
ATOM   4911 C CA  . GLU C 3 239 ? 167.009 112.249 188.425 1.00 152.65 ? 239 GLU A CA  1 
ATOM   4912 C C   . GLU C 3 239 ? 166.517 112.434 186.985 1.00 154.22 ? 239 GLU A C   1 
ATOM   4913 O O   . GLU C 3 239 ? 165.466 111.947 186.562 1.00 153.13 ? 239 GLU A O   1 
ATOM   4914 C CB  . GLU C 3 239 ? 166.718 110.857 188.984 1.00 150.83 ? 239 GLU A CB  1 
ATOM   4915 C CG  . GLU C 3 239 ? 165.253 110.391 189.013 1.00 150.83 ? 239 GLU A CG  1 
ATOM   4916 C CD  . GLU C 3 239 ? 164.401 111.091 190.063 1.00 152.80 ? 239 GLU A CD  1 
ATOM   4917 O OE1 . GLU C 3 239 ? 163.330 110.548 190.407 1.00 152.87 ? 239 GLU A OE1 1 
ATOM   4918 O OE2 . GLU C 3 239 ? 164.793 112.170 190.554 1.00 154.93 ? 239 GLU A OE2 1 
ATOM   4919 N N   . MET C 3 240 ? 167.311 113.182 186.222 1.00 149.38 ? 240 MET A N   1 
ATOM   4920 C CA  . MET C 3 240 ? 167.074 113.389 184.800 1.00 146.65 ? 240 MET A CA  1 
ATOM   4921 C C   . MET C 3 240 ? 168.365 113.830 184.129 1.00 147.40 ? 240 MET A C   1 
ATOM   4922 O O   . MET C 3 240 ? 169.205 114.490 184.749 1.00 148.19 ? 240 MET A O   1 
ATOM   4923 C CB  . MET C 3 240 ? 165.975 114.426 184.552 1.00 145.46 ? 240 MET A CB  1 
ATOM   4924 C CG  . MET C 3 240 ? 164.857 113.929 183.651 1.00 147.12 ? 240 MET A CG  1 
ATOM   4925 N N   . ASN C 3 241 ? 168.516 113.460 182.862 1.00 123.14 ? 241 ASN A N   1 
ATOM   4926 C CA  . ASN C 3 241 ? 169.722 113.792 182.116 1.00 119.84 ? 241 ASN A CA  1 
ATOM   4927 C C   . ASN C 3 241 ? 169.793 115.291 181.852 1.00 119.76 ? 241 ASN A C   1 
ATOM   4928 O O   . ASN C 3 241 ? 168.769 115.976 181.785 1.00 121.18 ? 241 ASN A O   1 
ATOM   4929 C CB  . ASN C 3 241 ? 169.750 113.015 180.799 1.00 119.51 ? 241 ASN A CB  1 
ATOM   4930 C CG  . ASN C 3 241 ? 171.067 113.154 180.058 1.00 122.06 ? 241 ASN A CG  1 
ATOM   4931 O OD1 . ASN C 3 241 ? 171.523 114.261 179.773 1.00 123.09 ? 241 ASN A OD1 1 
ATOM   4932 N ND2 . ASN C 3 241 ? 171.683 112.023 179.736 1.00 121.89 ? 241 ASN A ND2 1 
ATOM   4933 N N   . ARG C 3 242 ? 171.020 115.799 181.712 1.00 111.29 ? 242 ARG A N   1 
ATOM   4934 C CA  . ARG C 3 242 ? 171.209 117.192 181.319 1.00 111.33 ? 242 ARG A CA  1 
ATOM   4935 C C   . ARG C 3 242 ? 170.562 117.485 179.975 1.00 111.28 ? 242 ARG A C   1 
ATOM   4936 O O   . ARG C 3 242 ? 170.087 118.603 179.740 1.00 113.95 ? 242 ARG A O   1 
ATOM   4937 C CB  . ARG C 3 242 ? 172.698 117.528 181.238 1.00 111.46 ? 242 ARG A CB  1 
ATOM   4938 C CG  . ARG C 3 242 ? 173.448 117.579 182.553 1.00 113.68 ? 242 ARG A CG  1 
ATOM   4939 C CD  . ARG C 3 242 ? 174.609 118.557 182.438 1.00 111.43 ? 242 ARG A CD  1 
ATOM   4940 N NE  . ARG C 3 242 ? 175.539 118.462 183.555 1.00 111.25 ? 242 ARG A NE  1 
ATOM   4941 C CZ  . ARG C 3 242 ? 176.711 117.843 183.502 1.00 113.06 ? 242 ARG A CZ  1 
ATOM   4942 N NH1 . ARG C 3 242 ? 177.131 117.254 182.394 1.00 115.56 ? 242 ARG A NH1 1 
ATOM   4943 N NH2 . ARG C 3 242 ? 177.480 117.815 184.586 1.00 110.37 ? 242 ARG A NH2 1 
ATOM   4944 N N   . MET C 3 243 ? 170.556 116.507 179.073 1.00 101.86 ? 243 MET A N   1 
ATOM   4945 C CA  . MET C 3 243 ? 170.109 116.779 177.715 1.00 103.88 ? 243 MET A CA  1 
ATOM   4946 C C   . MET C 3 243 ? 168.613 117.058 177.672 1.00 107.00 ? 243 MET A C   1 
ATOM   4947 O O   . MET C 3 243 ? 168.160 117.934 176.926 1.00 111.09 ? 243 MET A O   1 
ATOM   4948 C CB  . MET C 3 243 ? 170.478 115.612 176.806 1.00 103.35 ? 243 MET A CB  1 
ATOM   4949 C CG  . MET C 3 243 ? 170.308 115.932 175.349 1.00 108.30 ? 243 MET A CG  1 
ATOM   4950 S SD  . MET C 3 243 ? 171.819 116.743 174.802 1.00 115.86 ? 243 MET A SD  1 
ATOM   4951 C CE  . MET C 3 243 ? 171.751 116.439 173.049 1.00 108.90 ? 243 MET A CE  1 
ATOM   4952 N N   . HIS C 3 244 ? 167.830 116.337 178.477 1.00 98.21  ? 244 HIS A N   1 
ATOM   4953 C CA  . HIS C 3 244 ? 166.389 116.566 178.493 1.00 99.09  ? 244 HIS A CA  1 
ATOM   4954 C C   . HIS C 3 244 ? 166.046 117.931 179.077 1.00 100.82 ? 244 HIS A C   1 
ATOM   4955 O O   . HIS C 3 244 ? 165.140 118.610 178.581 1.00 101.42 ? 244 HIS A O   1 
ATOM   4956 C CB  . HIS C 3 244 ? 165.687 115.451 179.264 1.00 96.66  ? 244 HIS A CB  1 
ATOM   4957 C CG  . HIS C 3 244 ? 165.500 114.198 178.467 1.00 95.44  ? 244 HIS A CG  1 
ATOM   4958 N ND1 . HIS C 3 244 ? 164.272 113.597 178.300 1.00 97.10  ? 244 HIS A ND1 1 
ATOM   4959 C CD2 . HIS C 3 244 ? 166.388 113.436 177.785 1.00 96.37  ? 244 HIS A CD2 1 
ATOM   4960 C CE1 . HIS C 3 244 ? 164.411 112.517 177.552 1.00 97.08  ? 244 HIS A CE1 1 
ATOM   4961 N NE2 . HIS C 3 244 ? 165.685 112.397 177.226 1.00 94.89  ? 244 HIS A NE2 1 
ATOM   4962 N N   . GLU C 3 245 ? 166.754 118.361 180.125 1.00 108.64 ? 245 GLU A N   1 
ATOM   4963 C CA  . GLU C 3 245 ? 166.489 119.690 180.667 1.00 110.67 ? 245 GLU A CA  1 
ATOM   4964 C C   . GLU C 3 245 ? 166.949 120.784 179.710 1.00 111.64 ? 245 GLU A C   1 
ATOM   4965 O O   . GLU C 3 245 ? 166.308 121.840 179.623 1.00 114.95 ? 245 GLU A O   1 
ATOM   4966 C CB  . GLU C 3 245 ? 167.138 119.852 182.044 1.00 112.55 ? 245 GLU A CB  1 
ATOM   4967 C CG  . GLU C 3 245 ? 168.654 119.921 182.052 1.00 115.27 ? 245 GLU A CG  1 
ATOM   4968 C CD  . GLU C 3 245 ? 169.180 121.343 182.067 1.00 118.57 ? 245 GLU A CD  1 
ATOM   4969 O OE1 . GLU C 3 245 ? 168.506 122.222 182.643 1.00 119.89 ? 245 GLU A OE1 1 
ATOM   4970 O OE2 . GLU C 3 245 ? 170.269 121.581 181.503 1.00 118.43 ? 245 GLU A OE2 1 
ATOM   4971 N N   . SER C 3 246 ? 168.039 120.551 178.974 1.00 89.00  ? 246 SER A N   1 
ATOM   4972 C CA  . SER C 3 246 ? 168.432 121.497 177.935 1.00 90.57  ? 246 SER A CA  1 
ATOM   4973 C C   . SER C 3 246 ? 167.363 121.591 176.851 1.00 95.26  ? 246 SER A C   1 
ATOM   4974 O O   . SER C 3 246 ? 167.045 122.687 176.370 1.00 98.72  ? 246 SER A O   1 
ATOM   4975 C CB  . SER C 3 246 ? 169.775 121.089 177.337 1.00 91.92  ? 246 SER A CB  1 
ATOM   4976 O OG  . SER C 3 246 ? 170.367 122.168 176.636 1.00 100.13 ? 246 SER A OG  1 
ATOM   4977 N N   . MET C 3 247 ? 166.789 120.450 176.462 1.00 90.03  ? 247 MET A N   1 
ATOM   4978 C CA  . MET C 3 247 ? 165.691 120.462 175.500 1.00 91.61  ? 247 MET A CA  1 
ATOM   4979 C C   . MET C 3 247 ? 164.485 121.213 176.046 1.00 92.17  ? 247 MET A C   1 
ATOM   4980 O O   . MET C 3 247 ? 163.812 121.941 175.308 1.00 95.94  ? 247 MET A O   1 
ATOM   4981 C CB  . MET C 3 247 ? 165.295 119.035 175.128 1.00 92.94  ? 247 MET A CB  1 
ATOM   4982 C CG  . MET C 3 247 ? 166.315 118.292 174.295 1.00 94.67  ? 247 MET A CG  1 
ATOM   4983 S SD  . MET C 3 247 ? 165.550 116.926 173.407 1.00 103.65 ? 247 MET A SD  1 
ATOM   4984 C CE  . MET C 3 247 ? 166.939 115.815 173.251 1.00 92.54  ? 247 MET A CE  1 
ATOM   4985 N N   . LYS C 3 248 ? 164.180 121.027 177.330 1.00 81.98  ? 248 LYS A N   1 
ATOM   4986 C CA  . LYS C 3 248 ? 163.057 121.738 177.933 1.00 82.90  ? 248 LYS A CA  1 
ATOM   4987 C C   . LYS C 3 248 ? 163.285 123.243 177.910 1.00 84.30  ? 248 LYS A C   1 
ATOM   4988 O O   . LYS C 3 248 ? 162.370 124.014 177.596 1.00 89.92  ? 248 LYS A O   1 
ATOM   4989 C CB  . LYS C 3 248 ? 162.835 121.251 179.363 1.00 87.76  ? 248 LYS A CB  1 
ATOM   4990 C CG  . LYS C 3 248 ? 161.714 120.236 179.505 1.00 91.97  ? 248 LYS A CG  1 
ATOM   4991 N N   . LEU C 3 249 ? 164.503 123.680 178.237 1.00 76.05  ? 249 LEU A N   1 
ATOM   4992 C CA  . LEU C 3 249 ? 164.815 125.105 178.187 1.00 78.94  ? 249 LEU A CA  1 
ATOM   4993 C C   . LEU C 3 249 ? 164.691 125.642 176.765 1.00 80.40  ? 249 LEU A C   1 
ATOM   4994 O O   . LEU C 3 249 ? 164.145 126.734 176.550 1.00 87.53  ? 249 LEU A O   1 
ATOM   4995 C CB  . LEU C 3 249 ? 166.221 125.347 178.739 1.00 81.09  ? 249 LEU A CB  1 
ATOM   4996 C CG  . LEU C 3 249 ? 166.571 126.686 179.398 1.00 82.10  ? 249 LEU A CG  1 
ATOM   4997 C CD1 . LEU C 3 249 ? 167.921 126.581 180.088 1.00 81.85  ? 249 LEU A CD1 1 
ATOM   4998 C CD2 . LEU C 3 249 ? 166.573 127.842 178.412 1.00 79.08  ? 249 LEU A CD2 1 
ATOM   4999 N N   . PHE C 3 250 ? 165.188 124.887 175.781 1.00 68.26  ? 250 PHE A N   1 
ATOM   5000 C CA  . PHE C 3 250 ? 165.080 125.323 174.392 1.00 67.86  ? 250 PHE A CA  1 
ATOM   5001 C C   . PHE C 3 250 ? 163.626 125.432 173.956 1.00 72.40  ? 250 PHE A C   1 
ATOM   5002 O O   . PHE C 3 250 ? 163.247 126.385 173.266 1.00 75.28  ? 250 PHE A O   1 
ATOM   5003 C CB  . PHE C 3 250 ? 165.836 124.365 173.476 1.00 67.27  ? 250 PHE A CB  1 
ATOM   5004 C CG  . PHE C 3 250 ? 165.996 124.873 172.075 1.00 67.41  ? 250 PHE A CG  1 
ATOM   5005 C CD1 . PHE C 3 250 ? 167.034 125.726 171.751 1.00 73.55  ? 250 PHE A CD1 1 
ATOM   5006 C CD2 . PHE C 3 250 ? 165.108 124.504 171.085 1.00 63.80  ? 250 PHE A CD2 1 
ATOM   5007 C CE1 . PHE C 3 250 ? 167.182 126.197 170.467 1.00 70.06  ? 250 PHE A CE1 1 
ATOM   5008 C CE2 . PHE C 3 250 ? 165.251 124.973 169.801 1.00 61.93  ? 250 PHE A CE2 1 
ATOM   5009 C CZ  . PHE C 3 250 ? 166.289 125.819 169.491 1.00 65.88  ? 250 PHE A CZ  1 
ATOM   5010 N N   . ASP C 3 251 ? 162.798 124.458 174.337 1.00 83.32  ? 251 ASP A N   1 
ATOM   5011 C CA  . ASP C 3 251 ? 161.386 124.506 173.975 1.00 81.89  ? 251 ASP A CA  1 
ATOM   5012 C C   . ASP C 3 251 ? 160.687 125.676 174.652 1.00 82.24  ? 251 ASP A C   1 
ATOM   5013 O O   . ASP C 3 251 ? 159.795 126.300 174.065 1.00 86.83  ? 251 ASP A O   1 
ATOM   5014 C CB  . ASP C 3 251 ? 160.705 123.190 174.340 1.00 86.32  ? 251 ASP A CB  1 
ATOM   5015 C CG  . ASP C 3 251 ? 159.404 122.984 173.594 1.00 90.18  ? 251 ASP A CG  1 
ATOM   5016 O OD1 . ASP C 3 251 ? 158.606 122.121 174.015 1.00 94.06  ? 251 ASP A OD1 1 
ATOM   5017 O OD2 . ASP C 3 251 ? 159.179 123.687 172.588 1.00 86.00  ? 251 ASP A OD2 1 
ATOM   5018 N N   . SER C 3 252 ? 161.071 125.981 175.892 1.00 72.94  ? 252 SER A N   1 
ATOM   5019 C CA  . SER C 3 252 ? 160.489 127.127 176.580 1.00 75.36  ? 252 SER A CA  1 
ATOM   5020 C C   . SER C 3 252 ? 160.854 128.432 175.886 1.00 76.95  ? 252 SER A C   1 
ATOM   5021 O O   . SER C 3 252 ? 160.011 129.327 175.748 1.00 78.02  ? 252 SER A O   1 
ATOM   5022 C CB  . SER C 3 252 ? 160.946 127.150 178.037 1.00 77.73  ? 252 SER A CB  1 
ATOM   5023 O OG  . SER C 3 252 ? 160.935 128.470 178.552 1.00 81.32  ? 252 SER A OG  1 
ATOM   5024 N N   . ILE C 3 253 ? 162.104 128.561 175.443 1.00 72.28  ? 253 ILE A N   1 
ATOM   5025 C CA  . ILE C 3 253 ? 162.550 129.827 174.868 1.00 71.43  ? 253 ILE A CA  1 
ATOM   5026 C C   . ILE C 3 253 ? 162.023 130.008 173.449 1.00 76.86  ? 253 ILE A C   1 
ATOM   5027 O O   . ILE C 3 253 ? 161.501 131.073 173.099 1.00 81.73  ? 253 ILE A O   1 
ATOM   5028 C CB  . ILE C 3 253 ? 164.085 129.930 174.920 1.00 69.38  ? 253 ILE A CB  1 
ATOM   5029 C CG1 . ILE C 3 253 ? 164.528 130.419 176.296 1.00 72.43  ? 253 ILE A CG1 1 
ATOM   5030 C CG2 . ILE C 3 253 ? 164.599 130.864 173.840 1.00 72.58  ? 253 ILE A CG2 1 
ATOM   5031 C CD1 . ILE C 3 253 ? 164.226 131.877 176.540 1.00 74.42  ? 253 ILE A CD1 1 
ATOM   5032 N N   . CYS C 3 254 ? 162.135 128.978 172.614 1.00 83.22  ? 254 CYS A N   1 
ATOM   5033 C CA  . CYS C 3 254 ? 161.881 129.137 171.186 1.00 82.86  ? 254 CYS A CA  1 
ATOM   5034 C C   . CYS C 3 254 ? 160.414 128.972 170.802 1.00 83.04  ? 254 CYS A C   1 
ATOM   5035 O O   . CYS C 3 254 ? 160.094 129.049 169.611 1.00 83.83  ? 254 CYS A O   1 
ATOM   5036 C CB  . CYS C 3 254 ? 162.763 128.164 170.393 1.00 87.05  ? 254 CYS A CB  1 
ATOM   5037 S SG  . CYS C 3 254 ? 162.659 128.263 168.597 1.00 105.61 ? 254 CYS A SG  1 
ATOM   5038 N N   . ASN C 3 255 ? 159.517 128.753 171.767 1.00 85.97  ? 255 ASN A N   1 
ATOM   5039 C CA  . ASN C 3 255 ? 158.077 128.806 171.529 1.00 85.44  ? 255 ASN A CA  1 
ATOM   5040 C C   . ASN C 3 255 ? 157.391 129.846 172.406 1.00 86.67  ? 255 ASN A C   1 
ATOM   5041 O O   . ASN C 3 255 ? 156.169 129.798 172.576 1.00 87.59  ? 255 ASN A O   1 
ATOM   5042 C CB  . ASN C 3 255 ? 157.423 127.440 171.750 1.00 86.42  ? 255 ASN A CB  1 
ATOM   5043 C CG  . ASN C 3 255 ? 157.905 126.390 170.775 1.00 89.25  ? 255 ASN A CG  1 
ATOM   5044 O OD1 . ASN C 3 255 ? 159.058 126.390 170.364 1.00 90.68  ? 255 ASN A OD1 1 
ATOM   5045 N ND2 . ASN C 3 255 ? 157.012 125.484 170.398 1.00 90.96  ? 255 ASN A ND2 1 
ATOM   5046 N N   . ASN C 3 256 ? 158.148 130.782 172.970 1.00 82.40  ? 256 ASN A N   1 
ATOM   5047 C CA  . ASN C 3 256 ? 157.570 131.757 173.880 1.00 80.73  ? 256 ASN A CA  1 
ATOM   5048 C C   . ASN C 3 256 ? 156.684 132.745 173.127 1.00 83.67  ? 256 ASN A C   1 
ATOM   5049 O O   . ASN C 3 256 ? 156.831 132.965 171.921 1.00 87.80  ? 256 ASN A O   1 
ATOM   5050 C CB  . ASN C 3 256 ? 158.668 132.506 174.633 1.00 81.40  ? 256 ASN A CB  1 
ATOM   5051 C CG  . ASN C 3 256 ? 158.323 132.733 176.088 1.00 84.55  ? 256 ASN A CG  1 
ATOM   5052 O OD1 . ASN C 3 256 ? 157.303 132.251 176.578 1.00 87.29  ? 256 ASN A OD1 1 
ATOM   5053 N ND2 . ASN C 3 256 ? 159.174 133.470 176.790 1.00 86.62  ? 256 ASN A ND2 1 
ATOM   5054 N N   . LYS C 3 257 ? 155.745 133.341 173.865 1.00 66.80  ? 257 LYS A N   1 
ATOM   5055 C CA  . LYS C 3 257 ? 154.822 134.298 173.265 1.00 62.18  ? 257 LYS A CA  1 
ATOM   5056 C C   . LYS C 3 257 ? 155.553 135.540 172.769 1.00 68.15  ? 257 LYS A C   1 
ATOM   5057 O O   . LYS C 3 257 ? 155.246 136.061 171.690 1.00 66.72  ? 257 LYS A O   1 
ATOM   5058 C CB  . LYS C 3 257 ? 153.741 134.675 174.278 1.00 62.02  ? 257 LYS A CB  1 
ATOM   5059 C CG  . LYS C 3 257 ? 153.308 136.130 174.231 1.00 67.93  ? 257 LYS A CG  1 
ATOM   5060 C CD  . LYS C 3 257 ? 151.969 136.325 174.919 1.00 67.82  ? 257 LYS A CD  1 
ATOM   5061 C CE  . LYS C 3 257 ? 152.076 136.059 176.411 1.00 69.18  ? 257 LYS A CE  1 
ATOM   5062 N NZ  . LYS C 3 257 ? 150.758 136.168 177.092 1.00 69.84  ? 257 LYS A NZ  1 
ATOM   5063 N N   . TRP C 3 258 ? 156.526 136.029 173.540 1.00 73.40  ? 258 TRP A N   1 
ATOM   5064 C CA  . TRP C 3 258 ? 157.202 137.270 173.178 1.00 70.07  ? 258 TRP A CA  1 
ATOM   5065 C C   . TRP C 3 258 ? 158.162 137.066 172.013 1.00 68.88  ? 258 TRP A C   1 
ATOM   5066 O O   . TRP C 3 258 ? 158.272 137.930 171.136 1.00 69.30  ? 258 TRP A O   1 
ATOM   5067 C CB  . TRP C 3 258 ? 157.938 137.836 174.391 1.00 68.69  ? 258 TRP A CB  1 
ATOM   5068 C CG  . TRP C 3 258 ? 157.049 138.029 175.575 1.00 67.96  ? 258 TRP A CG  1 
ATOM   5069 C CD1 . TRP C 3 258 ? 157.086 137.339 176.748 1.00 70.43  ? 258 TRP A CD1 1 
ATOM   5070 C CD2 . TRP C 3 258 ? 155.979 138.972 175.698 1.00 66.47  ? 258 TRP A CD2 1 
ATOM   5071 N NE1 . TRP C 3 258 ? 156.108 137.794 177.596 1.00 70.30  ? 258 TRP A NE1 1 
ATOM   5072 C CE2 . TRP C 3 258 ? 155.414 138.797 176.974 1.00 69.11  ? 258 TRP A CE2 1 
ATOM   5073 C CE3 . TRP C 3 258 ? 155.444 139.947 174.852 1.00 71.71  ? 258 TRP A CE3 1 
ATOM   5074 C CZ2 . TRP C 3 258 ? 154.342 139.561 177.425 1.00 72.06  ? 258 TRP A CZ2 1 
ATOM   5075 C CZ3 . TRP C 3 258 ? 154.381 140.704 175.301 1.00 72.09  ? 258 TRP A CZ3 1 
ATOM   5076 C CH2 . TRP C 3 258 ? 153.841 140.507 176.575 1.00 72.71  ? 258 TRP A CH2 1 
ATOM   5077 N N   . PHE C 3 259 ? 158.866 135.936 171.985 1.00 70.17  ? 259 PHE A N   1 
ATOM   5078 C CA  . PHE C 3 259 ? 159.852 135.669 170.938 1.00 74.97  ? 259 PHE A CA  1 
ATOM   5079 C C   . PHE C 3 259 ? 159.183 134.940 169.772 1.00 76.61  ? 259 PHE A C   1 
ATOM   5080 O O   . PHE C 3 259 ? 159.425 133.763 169.497 1.00 76.10  ? 259 PHE A O   1 
ATOM   5081 C CB  . PHE C 3 259 ? 161.021 134.872 171.502 1.00 75.38  ? 259 PHE A CB  1 
ATOM   5082 C CG  . PHE C 3 259 ? 161.834 135.624 172.513 1.00 73.86  ? 259 PHE A CG  1 
ATOM   5083 C CD1 . PHE C 3 259 ? 162.757 136.571 172.112 1.00 74.87  ? 259 PHE A CD1 1 
ATOM   5084 C CD2 . PHE C 3 259 ? 161.681 135.377 173.863 1.00 74.30  ? 259 PHE A CD2 1 
ATOM   5085 C CE1 . PHE C 3 259 ? 163.507 137.260 173.040 1.00 74.77  ? 259 PHE A CE1 1 
ATOM   5086 C CE2 . PHE C 3 259 ? 162.429 136.062 174.793 1.00 75.98  ? 259 PHE A CE2 1 
ATOM   5087 C CZ  . PHE C 3 259 ? 163.344 137.004 174.382 1.00 74.68  ? 259 PHE A CZ  1 
ATOM   5088 N N   . THR C 3 260 ? 158.318 135.676 169.077 1.00 85.24  ? 260 THR A N   1 
ATOM   5089 C CA  . THR C 3 260 ? 157.614 135.143 167.920 1.00 82.88  ? 260 THR A CA  1 
ATOM   5090 C C   . THR C 3 260 ? 158.297 135.467 166.597 1.00 79.97  ? 260 THR A C   1 
ATOM   5091 O O   . THR C 3 260 ? 157.883 134.936 165.561 1.00 82.12  ? 260 THR A O   1 
ATOM   5092 C CB  . THR C 3 260 ? 156.173 135.669 167.890 1.00 84.62  ? 260 THR A CB  1 
ATOM   5093 O OG1 . THR C 3 260 ? 155.337 134.744 167.185 1.00 84.85  ? 260 THR A OG1 1 
ATOM   5094 C CG2 . THR C 3 260 ? 156.107 137.031 167.213 1.00 81.93  ? 260 THR A CG2 1 
ATOM   5095 N N   . ASP C 3 261 ? 159.331 136.310 166.603 1.00 84.08  ? 261 ASP A N   1 
ATOM   5096 C CA  . ASP C 3 261 ? 160.002 136.684 165.364 1.00 86.72  ? 261 ASP A CA  1 
ATOM   5097 C C   . ASP C 3 261 ? 161.518 136.768 165.496 1.00 87.41  ? 261 ASP A C   1 
ATOM   5098 O O   . ASP C 3 261 ? 162.152 137.471 164.699 1.00 91.57  ? 261 ASP A O   1 
ATOM   5099 C CB  . ASP C 3 261 ? 159.436 138.015 164.835 1.00 92.23  ? 261 ASP A CB  1 
ATOM   5100 C CG  . ASP C 3 261 ? 159.636 139.177 165.802 1.00 96.65  ? 261 ASP A CG  1 
ATOM   5101 O OD1 . ASP C 3 261 ? 160.752 139.361 166.333 1.00 95.78  ? 261 ASP A OD1 1 
ATOM   5102 O OD2 . ASP C 3 261 ? 158.658 139.919 166.033 1.00 96.46  ? 261 ASP A OD2 1 
ATOM   5103 N N   . THR C 3 262 ? 162.122 136.081 166.460 1.00 70.01  ? 262 THR A N   1 
ATOM   5104 C CA  . THR C 3 262 ? 163.558 136.132 166.681 1.00 69.88  ? 262 THR A CA  1 
ATOM   5105 C C   . THR C 3 262 ? 164.193 134.784 166.364 1.00 67.75  ? 262 THR A C   1 
ATOM   5106 O O   . THR C 3 262 ? 163.607 133.728 166.612 1.00 75.24  ? 262 THR A O   1 
ATOM   5107 C CB  . THR C 3 262 ? 163.881 136.527 168.125 1.00 71.08  ? 262 THR A CB  1 
ATOM   5108 O OG1 . THR C 3 262 ? 163.907 135.355 168.948 1.00 76.02  ? 262 THR A OG1 1 
ATOM   5109 C CG2 . THR C 3 262 ? 162.836 137.493 168.658 1.00 67.68  ? 262 THR A CG2 1 
ATOM   5110 N N   . SER C 3 263 ? 165.401 134.833 165.814 1.00 48.54  ? 263 SER A N   1 
ATOM   5111 C CA  . SER C 3 263 ? 166.124 133.635 165.424 1.00 55.81  ? 263 SER A CA  1 
ATOM   5112 C C   . SER C 3 263 ? 167.032 133.157 166.556 1.00 60.73  ? 263 SER A C   1 
ATOM   5113 O O   . SER C 3 263 ? 167.252 133.852 167.550 1.00 70.20  ? 263 SER A O   1 
ATOM   5114 C CB  . SER C 3 263 ? 166.939 133.895 164.159 1.00 61.36  ? 263 SER A CB  1 
ATOM   5115 O OG  . SER C 3 263 ? 166.254 134.778 163.288 1.00 61.94  ? 263 SER A OG  1 
ATOM   5116 N N   . ILE C 3 264 ? 167.563 131.948 166.391 1.00 46.92  ? 264 ILE A N   1 
ATOM   5117 C CA  . ILE C 3 264 ? 168.445 131.326 167.371 1.00 37.65  ? 264 ILE A CA  1 
ATOM   5118 C C   . ILE C 3 264 ? 169.736 130.917 166.676 1.00 42.99  ? 264 ILE A C   1 
ATOM   5119 O O   . ILE C 3 264 ? 169.716 130.457 165.530 1.00 61.05  ? 264 ILE A O   1 
ATOM   5120 C CB  . ILE C 3 264 ? 167.783 130.108 168.049 1.00 46.39  ? 264 ILE A CB  1 
ATOM   5121 C CG1 . ILE C 3 264 ? 166.294 130.365 168.284 1.00 49.78  ? 264 ILE A CG1 1 
ATOM   5122 C CG2 . ILE C 3 264 ? 168.478 129.782 169.359 1.00 55.39  ? 264 ILE A CG2 1 
ATOM   5123 C CD1 . ILE C 3 264 ? 166.007 131.284 169.439 1.00 49.52  ? 264 ILE A CD1 1 
ATOM   5124 N N   . ILE C 3 265 ? 170.857 131.083 167.375 1.00 46.88  ? 265 ILE A N   1 
ATOM   5125 C CA  . ILE C 3 265 ? 172.185 130.840 166.821 1.00 55.63  ? 265 ILE A CA  1 
ATOM   5126 C C   . ILE C 3 265 ? 172.820 129.680 167.580 1.00 62.93  ? 265 ILE A C   1 
ATOM   5127 O O   . ILE C 3 265 ? 174.020 129.697 167.874 1.00 67.92  ? 265 ILE A O   1 
ATOM   5128 C CB  . ILE C 3 265 ? 173.063 132.105 166.874 1.00 52.47  ? 265 ILE A CB  1 
ATOM   5129 C CG1 . ILE C 3 265 ? 172.265 133.325 166.426 1.00 57.98  ? 265 ILE A CG1 1 
ATOM   5130 C CG2 . ILE C 3 265 ? 174.257 131.976 165.944 1.00 51.00  ? 265 ILE A CG2 1 
ATOM   5131 C CD1 . ILE C 3 265 ? 172.942 134.636 166.742 1.00 64.00  ? 265 ILE A CD1 1 
ATOM   5132 N N   . LEU C 3 266 ? 172.000 128.692 167.933 1.00 61.54  ? 266 LEU A N   1 
ATOM   5133 C CA  . LEU C 3 266 ? 172.372 127.555 168.769 1.00 53.07  ? 266 LEU A CA  1 
ATOM   5134 C C   . LEU C 3 266 ? 173.775 127.038 168.486 1.00 42.26  ? 266 LEU A C   1 
ATOM   5135 O O   . LEU C 3 266 ? 174.105 126.686 167.349 1.00 55.12  ? 266 LEU A O   1 
ATOM   5136 C CB  . LEU C 3 266 ? 171.357 126.432 168.554 1.00 47.84  ? 266 LEU A CB  1 
ATOM   5137 C CG  . LEU C 3 266 ? 171.735 125.041 169.054 1.00 50.82  ? 266 LEU A CG  1 
ATOM   5138 C CD1 . LEU C 3 266 ? 171.687 124.987 170.571 1.00 59.13  ? 266 LEU A CD1 1 
ATOM   5139 C CD2 . LEU C 3 266 ? 170.818 123.999 168.446 1.00 52.75  ? 266 LEU A CD2 1 
ATOM   5140 N N   . PHE C 3 267 ? 174.599 126.993 169.527 1.00 49.07  ? 267 PHE A N   1 
ATOM   5141 C CA  . PHE C 3 267 ? 175.932 126.413 169.481 1.00 57.92  ? 267 PHE A CA  1 
ATOM   5142 C C   . PHE C 3 267 ? 175.916 125.020 170.098 1.00 66.01  ? 267 PHE A C   1 
ATOM   5143 O O   . PHE C 3 267 ? 175.086 124.703 170.953 1.00 77.83  ? 267 PHE A O   1 
ATOM   5144 C CB  . PHE C 3 267 ? 176.943 127.286 170.232 1.00 66.01  ? 267 PHE A CB  1 
ATOM   5145 C CG  . PHE C 3 267 ? 177.312 128.557 169.522 1.00 67.82  ? 267 PHE A CG  1 
ATOM   5146 C CD1 . PHE C 3 267 ? 176.507 129.675 169.613 1.00 65.83  ? 267 PHE A CD1 1 
ATOM   5147 C CD2 . PHE C 3 267 ? 178.474 128.637 168.778 1.00 67.05  ? 267 PHE A CD2 1 
ATOM   5148 C CE1 . PHE C 3 267 ? 176.848 130.843 168.966 1.00 64.01  ? 267 PHE A CE1 1 
ATOM   5149 C CE2 . PHE C 3 267 ? 178.818 129.803 168.129 1.00 63.04  ? 267 PHE A CE2 1 
ATOM   5150 C CZ  . PHE C 3 267 ? 178.006 130.905 168.223 1.00 61.74  ? 267 PHE A CZ  1 
ATOM   5151 N N   . LEU C 3 268 ? 176.852 124.186 169.653 1.00 67.18  ? 268 LEU A N   1 
ATOM   5152 C CA  . LEU C 3 268 ? 177.078 122.869 170.240 1.00 69.42  ? 268 LEU A CA  1 
ATOM   5153 C C   . LEU C 3 268 ? 178.521 122.835 170.721 1.00 75.21  ? 268 LEU A C   1 
ATOM   5154 O O   . LEU C 3 268 ? 179.450 122.860 169.908 1.00 83.04  ? 268 LEU A O   1 
ATOM   5155 C CB  . LEU C 3 268 ? 176.790 121.754 169.237 1.00 67.86  ? 268 LEU A CB  1 
ATOM   5156 C CG  . LEU C 3 268 ? 175.312 121.582 168.879 1.00 66.62  ? 268 LEU A CG  1 
ATOM   5157 C CD1 . LEU C 3 268 ? 175.096 120.305 168.091 1.00 70.46  ? 268 LEU A CD1 1 
ATOM   5158 C CD2 . LEU C 3 268 ? 174.449 121.595 170.124 1.00 67.86  ? 268 LEU A CD2 1 
ATOM   5159 N N   . ASN C 3 269 ? 178.708 122.774 172.039 1.00 76.86  ? 269 ASN A N   1 
ATOM   5160 C CA  . ASN C 3 269 ? 179.973 123.169 172.643 1.00 76.60  ? 269 ASN A CA  1 
ATOM   5161 C C   . ASN C 3 269 ? 180.987 122.042 172.775 1.00 77.18  ? 269 ASN A C   1 
ATOM   5162 O O   . ASN C 3 269 ? 182.168 122.261 172.482 1.00 83.71  ? 269 ASN A O   1 
ATOM   5163 C CB  . ASN C 3 269 ? 179.721 123.776 174.024 1.00 76.57  ? 269 ASN A CB  1 
ATOM   5164 C CG  . ASN C 3 269 ? 179.679 125.288 173.994 1.00 82.23  ? 269 ASN A CG  1 
ATOM   5165 O OD1 . ASN C 3 269 ? 180.683 125.941 173.714 1.00 83.51  ? 269 ASN A OD1 1 
ATOM   5166 N ND2 . ASN C 3 269 ? 178.514 125.854 174.280 1.00 85.74  ? 269 ASN A ND2 1 
ATOM   5167 N N   . LYS C 3 270 ? 180.575 120.855 173.200 1.00 76.57  ? 270 LYS A N   1 
ATOM   5168 C CA  . LYS C 3 270 ? 181.506 119.779 173.540 1.00 83.72  ? 270 LYS A CA  1 
ATOM   5169 C C   . LYS C 3 270 ? 181.640 118.854 172.333 1.00 90.86  ? 270 LYS A C   1 
ATOM   5170 O O   . LYS C 3 270 ? 180.918 117.865 172.207 1.00 96.12  ? 270 LYS A O   1 
ATOM   5171 C CB  . LYS C 3 270 ? 181.024 119.025 174.773 1.00 88.61  ? 270 LYS A CB  1 
ATOM   5172 C CG  . LYS C 3 270 ? 181.020 119.857 176.044 1.00 92.42  ? 270 LYS A CG  1 
ATOM   5173 C CD  . LYS C 3 270 ? 182.324 120.615 176.226 1.00 90.41  ? 270 LYS A CD  1 
ATOM   5174 C CE  . LYS C 3 270 ? 182.414 121.221 177.618 1.00 88.05  ? 270 LYS A CE  1 
ATOM   5175 N NZ  . LYS C 3 270 ? 183.749 121.822 177.878 1.00 87.13  ? 270 LYS A NZ  1 
ATOM   5176 N N   . LYS C 3 271 ? 182.592 119.167 171.455 1.00 83.02  ? 271 LYS A N   1 
ATOM   5177 C CA  . LYS C 3 271 ? 182.717 118.431 170.203 1.00 76.20  ? 271 LYS A CA  1 
ATOM   5178 C C   . LYS C 3 271 ? 183.709 117.278 170.280 1.00 78.76  ? 271 LYS A C   1 
ATOM   5179 O O   . LYS C 3 271 ? 183.515 116.258 169.611 1.00 83.89  ? 271 LYS A O   1 
ATOM   5180 C CB  . LYS C 3 271 ? 183.125 119.377 169.074 1.00 76.65  ? 271 LYS A CB  1 
ATOM   5181 C CG  . LYS C 3 271 ? 182.351 119.168 167.790 1.00 81.41  ? 271 LYS A CG  1 
ATOM   5182 C CD  . LYS C 3 271 ? 183.064 119.809 166.612 1.00 89.04  ? 271 LYS A CD  1 
ATOM   5183 C CE  . LYS C 3 271 ? 184.301 119.017 166.216 1.00 89.31  ? 271 LYS A CE  1 
ATOM   5184 N NZ  . LYS C 3 271 ? 185.177 119.780 165.283 1.00 89.03  ? 271 LYS A NZ  1 
ATOM   5185 N N   . ASP C 3 272 ? 184.771 117.407 171.075 1.00 81.75  ? 272 ASP A N   1 
ATOM   5186 C CA  . ASP C 3 272 ? 185.802 116.376 171.099 1.00 83.44  ? 272 ASP A CA  1 
ATOM   5187 C C   . ASP C 3 272 ? 185.757 115.476 172.332 1.00 83.55  ? 272 ASP A C   1 
ATOM   5188 O O   . ASP C 3 272 ? 186.330 114.382 172.293 1.00 87.02  ? 272 ASP A O   1 
ATOM   5189 C CB  . ASP C 3 272 ? 187.196 117.011 170.920 1.00 88.10  ? 272 ASP A CB  1 
ATOM   5190 C CG  . ASP C 3 272 ? 187.681 117.788 172.142 1.00 90.95  ? 272 ASP A CG  1 
ATOM   5191 O OD1 . ASP C 3 272 ? 188.616 118.602 171.972 1.00 87.50  ? 272 ASP A OD1 1 
ATOM   5192 O OD2 . ASP C 3 272 ? 187.151 117.624 173.251 1.00 91.42  ? 272 ASP A OD2 1 
ATOM   5193 N N   . LEU C 3 273 ? 185.101 115.895 173.419 1.00 88.03  ? 273 LEU A N   1 
ATOM   5194 C CA  . LEU C 3 273 ? 184.750 114.927 174.455 1.00 94.01  ? 273 LEU A CA  1 
ATOM   5195 C C   . LEU C 3 273 ? 183.713 113.936 173.946 1.00 96.86  ? 273 LEU A C   1 
ATOM   5196 O O   . LEU C 3 273 ? 183.689 112.779 174.386 1.00 100.25 ? 273 LEU A O   1 
ATOM   5197 C CB  . LEU C 3 273 ? 184.217 115.620 175.714 1.00 94.79  ? 273 LEU A CB  1 
ATOM   5198 C CG  . LEU C 3 273 ? 185.030 116.553 176.623 1.00 95.29  ? 273 LEU A CG  1 
ATOM   5199 C CD1 . LEU C 3 273 ? 184.134 117.173 177.694 1.00 92.60  ? 273 LEU A CD1 1 
ATOM   5200 C CD2 . LEU C 3 273 ? 186.262 115.914 177.241 1.00 93.08  ? 273 LEU A CD2 1 
ATOM   5201 N N   . PHE C 3 274 ? 182.853 114.383 173.029 1.00 83.10  ? 274 PHE A N   1 
ATOM   5202 C CA  . PHE C 3 274 ? 181.789 113.535 172.506 1.00 78.44  ? 274 PHE A CA  1 
ATOM   5203 C C   . PHE C 3 274 ? 182.357 112.310 171.803 1.00 86.53  ? 274 PHE A C   1 
ATOM   5204 O O   . PHE C 3 274 ? 181.820 111.204 171.938 1.00 93.03  ? 274 PHE A O   1 
ATOM   5205 C CB  . PHE C 3 274 ? 180.917 114.345 171.549 1.00 77.46  ? 274 PHE A CB  1 
ATOM   5206 C CG  . PHE C 3 274 ? 179.593 113.717 171.249 1.00 75.58  ? 274 PHE A CG  1 
ATOM   5207 C CD1 . PHE C 3 274 ? 179.067 113.766 169.973 1.00 78.52  ? 274 PHE A CD1 1 
ATOM   5208 C CD2 . PHE C 3 274 ? 178.862 113.102 172.245 1.00 82.05  ? 274 PHE A CD2 1 
ATOM   5209 C CE1 . PHE C 3 274 ? 177.849 113.197 169.691 1.00 81.09  ? 274 PHE A CE1 1 
ATOM   5210 C CE2 . PHE C 3 274 ? 177.638 112.535 171.969 1.00 86.17  ? 274 PHE A CE2 1 
ATOM   5211 C CZ  . PHE C 3 274 ? 177.132 112.581 170.690 1.00 82.63  ? 274 PHE A CZ  1 
ATOM   5212 N N   . GLU C 3 275 ? 183.435 112.490 171.038 1.00 91.78  ? 275 GLU A N   1 
ATOM   5213 C CA  . GLU C 3 275 ? 184.045 111.367 170.335 1.00 86.89  ? 275 GLU A CA  1 
ATOM   5214 C C   . GLU C 3 275 ? 184.458 110.274 171.310 1.00 88.30  ? 275 GLU A C   1 
ATOM   5215 O O   . GLU C 3 275 ? 184.116 109.100 171.128 1.00 93.98  ? 275 GLU A O   1 
ATOM   5216 C CB  . GLU C 3 275 ? 185.248 111.850 169.527 1.00 87.00  ? 275 GLU A CB  1 
ATOM   5217 C CG  . GLU C 3 275 ? 184.896 112.761 168.370 1.00 92.32  ? 275 GLU A CG  1 
ATOM   5218 C CD  . GLU C 3 275 ? 184.997 112.064 167.032 1.00 96.83  ? 275 GLU A CD  1 
ATOM   5219 O OE1 . GLU C 3 275 ? 185.093 110.819 167.017 1.00 93.75  ? 275 GLU A OE1 1 
ATOM   5220 O OE2 . GLU C 3 275 ? 184.982 112.760 165.996 1.00 98.09  ? 275 GLU A OE2 1 
ATOM   5221 N N   . GLU C 3 276 ? 185.181 110.648 172.367 1.00 88.81  ? 276 GLU A N   1 
ATOM   5222 C CA  . GLU C 3 276 ? 185.617 109.664 173.350 1.00 94.38  ? 276 GLU A CA  1 
ATOM   5223 C C   . GLU C 3 276 ? 184.433 109.038 174.075 1.00 93.98  ? 276 GLU A C   1 
ATOM   5224 O O   . GLU C 3 276 ? 184.425 107.827 174.331 1.00 98.57  ? 276 GLU A O   1 
ATOM   5225 C CB  . GLU C 3 276 ? 186.582 110.305 174.352 1.00 93.45  ? 276 GLU A CB  1 
ATOM   5226 C CG  . GLU C 3 276 ? 187.676 111.249 173.802 1.00 91.96  ? 276 GLU A CG  1 
ATOM   5227 C CD  . GLU C 3 276 ? 188.120 110.996 172.361 1.00 96.45  ? 276 GLU A CD  1 
ATOM   5228 O OE1 . GLU C 3 276 ? 188.140 109.833 171.903 1.00 94.94  ? 276 GLU A OE1 1 
ATOM   5229 O OE2 . GLU C 3 276 ? 188.453 111.984 171.675 1.00 99.46  ? 276 GLU A OE2 1 
ATOM   5230 N N   . LYS C 3 277 ? 183.426 109.845 174.422 1.00 87.18  ? 277 LYS A N   1 
ATOM   5231 C CA  . LYS C 3 277 ? 182.286 109.304 175.154 1.00 88.77  ? 277 LYS A CA  1 
ATOM   5232 C C   . LYS C 3 277 ? 181.537 108.267 174.327 1.00 93.77  ? 277 LYS A C   1 
ATOM   5233 O O   . LYS C 3 277 ? 181.187 107.196 174.836 1.00 96.27  ? 277 LYS A O   1 
ATOM   5234 C CB  . LYS C 3 277 ? 181.349 110.431 175.585 1.00 95.52  ? 277 LYS A CB  1 
ATOM   5235 C CG  . LYS C 3 277 ? 181.955 111.383 176.601 1.00 96.96  ? 277 LYS A CG  1 
ATOM   5236 C CD  . LYS C 3 277 ? 181.736 110.887 178.019 1.00 94.40  ? 277 LYS A CD  1 
ATOM   5237 C CE  . LYS C 3 277 ? 181.371 112.029 178.950 1.00 95.97  ? 277 LYS A CE  1 
ATOM   5238 N NZ  . LYS C 3 277 ? 182.278 113.195 178.772 1.00 96.76  ? 277 LYS A NZ  1 
ATOM   5239 N N   . ILE C 3 278 ? 181.284 108.558 173.049 1.00 87.61  ? 278 ILE A N   1 
ATOM   5240 C CA  . ILE C 3 278 ? 180.607 107.579 172.203 1.00 82.91  ? 278 ILE A CA  1 
ATOM   5241 C C   . ILE C 3 278 ? 181.523 106.435 171.797 1.00 82.63  ? 278 ILE A C   1 
ATOM   5242 O O   . ILE C 3 278 ? 181.033 105.378 171.385 1.00 83.92  ? 278 ILE A O   1 
ATOM   5243 C CB  . ILE C 3 278 ? 179.982 108.240 170.962 1.00 81.53  ? 278 ILE A CB  1 
ATOM   5244 C CG1 . ILE C 3 278 ? 180.993 108.331 169.822 1.00 83.78  ? 278 ILE A CG1 1 
ATOM   5245 C CG2 . ILE C 3 278 ? 179.347 109.576 171.308 1.00 88.26  ? 278 ILE A CG2 1 
ATOM   5246 C CD1 . ILE C 3 278 ? 180.357 108.550 168.486 1.00 86.88  ? 278 ILE A CD1 1 
ATOM   5247 N N   . LYS C 3 279 ? 182.841 106.609 171.900 1.00 90.43  ? 279 LYS A N   1 
ATOM   5248 C CA  . LYS C 3 279 ? 183.736 105.467 171.762 1.00 90.31  ? 279 LYS A CA  1 
ATOM   5249 C C   . LYS C 3 279 ? 183.561 104.501 172.926 1.00 87.02  ? 279 LYS A C   1 
ATOM   5250 O O   . LYS C 3 279 ? 183.382 103.294 172.727 1.00 80.94  ? 279 LYS A O   1 
ATOM   5251 C CB  . LYS C 3 279 ? 185.184 105.947 171.671 1.00 89.97  ? 279 LYS A CB  1 
ATOM   5252 C CG  . LYS C 3 279 ? 185.507 106.727 170.410 1.00 88.40  ? 279 LYS A CG  1 
ATOM   5253 C CD  . LYS C 3 279 ? 186.950 107.189 170.405 1.00 89.06  ? 279 LYS A CD  1 
ATOM   5254 C CE  . LYS C 3 279 ? 187.278 107.948 169.132 1.00 91.01  ? 279 LYS A CE  1 
ATOM   5255 N NZ  . LYS C 3 279 ? 188.688 108.430 169.121 1.00 90.02  ? 279 LYS A NZ  1 
ATOM   5256 N N   . LYS C 3 280 ? 183.593 105.021 174.156 1.00 106.18 ? 280 LYS A N   1 
ATOM   5257 C CA  . LYS C 3 280 ? 183.551 104.156 175.330 1.00 106.84 ? 280 LYS A CA  1 
ATOM   5258 C C   . LYS C 3 280 ? 182.135 103.727 175.699 1.00 107.41 ? 280 LYS A C   1 
ATOM   5259 O O   . LYS C 3 280 ? 181.954 102.641 176.259 1.00 106.14 ? 280 LYS A O   1 
ATOM   5260 C CB  . LYS C 3 280 ? 184.218 104.853 176.519 1.00 106.95 ? 280 LYS A CB  1 
ATOM   5261 C CG  . LYS C 3 280 ? 183.433 106.025 177.088 1.00 109.54 ? 280 LYS A CG  1 
ATOM   5262 C CD  . LYS C 3 280 ? 183.771 106.259 178.552 1.00 107.80 ? 280 LYS A CD  1 
ATOM   5263 C CE  . LYS C 3 280 ? 185.119 106.945 178.705 1.00 108.16 ? 280 LYS A CE  1 
ATOM   5264 N NZ  . LYS C 3 280 ? 185.052 108.389 178.349 1.00 107.38 ? 280 LYS A NZ  1 
ATOM   5265 N N   . SER C 3 281 ? 181.123 104.549 175.403 1.00 104.76 ? 281 SER A N   1 
ATOM   5266 C CA  . SER C 3 281 ? 179.757 104.255 175.822 1.00 101.80 ? 281 SER A CA  1 
ATOM   5267 C C   . SER C 3 281 ? 178.774 104.617 174.714 1.00 99.00  ? 281 SER A C   1 
ATOM   5268 O O   . SER C 3 281 ? 178.824 105.743 174.187 1.00 99.72  ? 281 SER A O   1 
ATOM   5269 C CB  . SER C 3 281 ? 179.404 105.009 177.107 1.00 99.18  ? 281 SER A CB  1 
ATOM   5270 O OG  . SER C 3 281 ? 178.002 105.031 177.311 1.00 99.85  ? 281 SER A OG  1 
ATOM   5271 N N   . PRO C 3 282 ? 177.876 103.711 174.347 1.00 95.17  ? 282 PRO A N   1 
ATOM   5272 C CA  . PRO C 3 282 ? 176.921 103.995 173.274 1.00 98.36  ? 282 PRO A CA  1 
ATOM   5273 C C   . PRO C 3 282 ? 175.799 104.913 173.744 1.00 101.51 ? 282 PRO A C   1 
ATOM   5274 O O   . PRO C 3 282 ? 175.692 105.272 174.917 1.00 100.94 ? 282 PRO A O   1 
ATOM   5275 C CB  . PRO C 3 282 ? 176.382 102.610 172.904 1.00 101.63 ? 282 PRO A CB  1 
ATOM   5276 C CG  . PRO C 3 282 ? 176.553 101.802 174.143 1.00 99.96  ? 282 PRO A CG  1 
ATOM   5277 C CD  . PRO C 3 282 ? 177.792 102.317 174.816 1.00 95.88  ? 282 PRO A CD  1 
ATOM   5278 N N   . LEU C 3 283 ? 174.952 105.288 172.787 1.00 104.51 ? 283 LEU A N   1 
ATOM   5279 C CA  . LEU C 3 283 ? 173.799 106.154 173.029 1.00 102.04 ? 283 LEU A CA  1 
ATOM   5280 C C   . LEU C 3 283 ? 172.618 105.283 173.438 1.00 101.01 ? 283 LEU A C   1 
ATOM   5281 O O   . LEU C 3 283 ? 171.795 104.881 172.614 1.00 100.20 ? 283 LEU A O   1 
ATOM   5282 C CB  . LEU C 3 283 ? 173.488 106.980 171.789 1.00 96.89  ? 283 LEU A CB  1 
ATOM   5283 C CG  . LEU C 3 283 ? 172.429 108.075 171.893 1.00 96.60  ? 283 LEU A CG  1 
ATOM   5284 C CD1 . LEU C 3 283 ? 172.671 108.946 173.107 1.00 101.66 ? 283 LEU A CD1 1 
ATOM   5285 C CD2 . LEU C 3 283 ? 172.459 108.913 170.634 1.00 99.43  ? 283 LEU A CD2 1 
ATOM   5286 N N   . THR C 3 284 ? 172.532 104.987 174.734 1.00 117.71 ? 284 THR A N   1 
ATOM   5287 C CA  . THR C 3 284 ? 171.510 104.076 175.234 1.00 120.98 ? 284 THR A CA  1 
ATOM   5288 C C   . THR C 3 284 ? 170.712 104.689 176.378 1.00 117.67 ? 284 THR A C   1 
ATOM   5289 O O   . THR C 3 284 ? 169.518 104.406 176.525 1.00 120.29 ? 284 THR A O   1 
ATOM   5290 C CB  . THR C 3 284 ? 172.145 102.760 175.689 1.00 122.52 ? 284 THR A CB  1 
ATOM   5291 O OG1 . THR C 3 284 ? 173.291 103.035 176.504 1.00 121.80 ? 284 THR A OG1 1 
ATOM   5292 C CG2 . THR C 3 284 ? 172.571 101.929 174.486 1.00 118.24 ? 284 THR A CG2 1 
ATOM   5293 N N   . ILE C 3 285 ? 171.358 105.525 177.196 1.00 112.12 ? 285 ILE A N   1 
ATOM   5294 C CA  . ILE C 3 285 ? 170.691 106.083 178.368 1.00 115.86 ? 285 ILE A CA  1 
ATOM   5295 C C   . ILE C 3 285 ? 169.535 106.997 177.984 1.00 117.48 ? 285 ILE A C   1 
ATOM   5296 O O   . ILE C 3 285 ? 168.690 107.311 178.830 1.00 116.41 ? 285 ILE A O   1 
ATOM   5297 C CB  . ILE C 3 285 ? 171.705 106.825 179.258 1.00 119.90 ? 285 ILE A CB  1 
ATOM   5298 C CG1 . ILE C 3 285 ? 171.243 106.813 180.717 1.00 117.69 ? 285 ILE A CG1 1 
ATOM   5299 C CG2 . ILE C 3 285 ? 171.913 108.252 178.769 1.00 118.15 ? 285 ILE A CG2 1 
ATOM   5300 C CD1 . ILE C 3 285 ? 171.230 105.434 181.340 1.00 114.47 ? 285 ILE A CD1 1 
ATOM   5301 N N   . CYS C 3 286 ? 169.475 107.434 176.729 1.00 114.15 ? 286 CYS A N   1 
ATOM   5302 C CA  . CYS C 3 286 ? 168.349 108.204 176.221 1.00 110.89 ? 286 CYS A CA  1 
ATOM   5303 C C   . CYS C 3 286 ? 168.226 107.924 174.729 1.00 110.89 ? 286 CYS A C   1 
ATOM   5304 O O   . CYS C 3 286 ? 168.977 107.121 174.168 1.00 108.45 ? 286 CYS A O   1 
ATOM   5305 C CB  . CYS C 3 286 ? 168.520 109.696 176.525 1.00 111.37 ? 286 CYS A CB  1 
ATOM   5306 S SG  . CYS C 3 286 ? 167.144 110.738 176.017 1.00 118.93 ? 286 CYS A SG  1 
ATOM   5307 N N   . TYR C 3 287 ? 167.272 108.602 174.084 1.00 108.48 ? 287 TYR A N   1 
ATOM   5308 C CA  . TYR C 3 287 ? 166.943 108.353 172.683 1.00 110.54 ? 287 TYR A CA  1 
ATOM   5309 C C   . TYR C 3 287 ? 166.665 106.874 172.440 1.00 109.12 ? 287 TYR A C   1 
ATOM   5310 O O   . TYR C 3 287 ? 167.526 106.162 171.908 1.00 104.78 ? 287 TYR A O   1 
ATOM   5311 C CB  . TYR C 3 287 ? 168.054 108.831 171.746 1.00 109.44 ? 287 TYR A CB  1 
ATOM   5312 C CG  . TYR C 3 287 ? 168.442 110.279 171.918 1.00 106.94 ? 287 TYR A CG  1 
ATOM   5313 C CD1 . TYR C 3 287 ? 167.479 111.259 172.104 1.00 105.88 ? 287 TYR A CD1 1 
ATOM   5314 C CD2 . TYR C 3 287 ? 169.769 110.668 171.863 1.00 105.89 ? 287 TYR A CD2 1 
ATOM   5315 C CE1 . TYR C 3 287 ? 167.832 112.582 172.252 1.00 103.96 ? 287 TYR A CE1 1 
ATOM   5316 C CE2 . TYR C 3 287 ? 170.129 111.983 172.010 1.00 106.96 ? 287 TYR A CE2 1 
ATOM   5317 C CZ  . TYR C 3 287 ? 169.159 112.938 172.203 1.00 107.05 ? 287 TYR A CZ  1 
ATOM   5318 O OH  . TYR C 3 287 ? 169.527 114.253 172.346 1.00 109.50 ? 287 TYR A OH  1 
ATOM   5319 N N   . PRO C 3 288 ? 165.495 106.371 172.841 1.00 116.26 ? 288 PRO A N   1 
ATOM   5320 C CA  . PRO C 3 288 ? 165.178 104.959 172.570 1.00 116.19 ? 288 PRO A CA  1 
ATOM   5321 C C   . PRO C 3 288 ? 165.242 104.603 171.096 1.00 116.31 ? 288 PRO A C   1 
ATOM   5322 O O   . PRO C 3 288 ? 165.531 103.447 170.760 1.00 117.09 ? 288 PRO A O   1 
ATOM   5323 C CB  . PRO C 3 288 ? 163.756 104.801 173.129 1.00 114.41 ? 288 PRO A CB  1 
ATOM   5324 C CG  . PRO C 3 288 ? 163.548 105.974 174.032 1.00 112.63 ? 288 PRO A CG  1 
ATOM   5325 C CD  . PRO C 3 288 ? 164.375 107.083 173.476 1.00 114.45 ? 288 PRO A CD  1 
ATOM   5326 N N   . GLU C 3 289 ? 164.983 105.556 170.206 1.00 115.02 ? 289 GLU A N   1 
ATOM   5327 C CA  . GLU C 3 289 ? 165.138 105.307 168.783 1.00 112.79 ? 289 GLU A CA  1 
ATOM   5328 C C   . GLU C 3 289 ? 166.614 105.144 168.429 1.00 113.02 ? 289 GLU A C   1 
ATOM   5329 O O   . GLU C 3 289 ? 167.511 105.532 169.182 1.00 111.99 ? 289 GLU A O   1 
ATOM   5330 C CB  . GLU C 3 289 ? 164.520 106.441 167.966 1.00 113.79 ? 289 GLU A CB  1 
ATOM   5331 C CG  . GLU C 3 289 ? 163.099 106.167 167.500 1.00 115.74 ? 289 GLU A CG  1 
ATOM   5332 C CD  . GLU C 3 289 ? 162.086 106.245 168.627 1.00 118.36 ? 289 GLU A CD  1 
ATOM   5333 O OE1 . GLU C 3 289 ? 162.405 106.841 169.678 1.00 118.12 ? 289 GLU A OE1 1 
ATOM   5334 O OE2 . GLU C 3 289 ? 160.970 105.709 168.463 1.00 118.16 ? 289 GLU A OE2 1 
ATOM   5335 N N   . TYR C 3 290 ? 166.856 104.557 167.261 1.00 117.45 ? 290 TYR A N   1 
ATOM   5336 C CA  . TYR C 3 290 ? 168.213 104.234 166.848 1.00 117.62 ? 290 TYR A CA  1 
ATOM   5337 C C   . TYR C 3 290 ? 169.029 105.495 166.581 1.00 117.84 ? 290 TYR A C   1 
ATOM   5338 O O   . TYR C 3 290 ? 168.515 106.513 166.110 1.00 119.01 ? 290 TYR A O   1 
ATOM   5339 C CB  . TYR C 3 290 ? 168.190 103.349 165.602 1.00 114.65 ? 290 TYR A CB  1 
ATOM   5340 C CG  . TYR C 3 290 ? 168.139 104.112 164.298 1.00 116.99 ? 290 TYR A CG  1 
ATOM   5341 C CD1 . TYR C 3 290 ? 167.034 104.884 163.965 1.00 119.36 ? 290 TYR A CD1 1 
ATOM   5342 C CD2 . TYR C 3 290 ? 169.190 104.052 163.397 1.00 115.91 ? 290 TYR A CD2 1 
ATOM   5343 C CE1 . TYR C 3 290 ? 166.983 105.583 162.774 1.00 119.41 ? 290 TYR A CE1 1 
ATOM   5344 C CE2 . TYR C 3 290 ? 169.150 104.747 162.203 1.00 119.01 ? 290 TYR A CE2 1 
ATOM   5345 C CZ  . TYR C 3 290 ? 168.043 105.510 161.896 1.00 119.56 ? 290 TYR A CZ  1 
ATOM   5346 O OH  . TYR C 3 290 ? 167.997 106.202 160.708 1.00 117.87 ? 290 TYR A OH  1 
ATOM   5347 N N   . ALA C 3 291 ? 170.317 105.420 166.910 1.00 114.69 ? 291 ALA A N   1 
ATOM   5348 C CA  . ALA C 3 291 ? 171.278 106.468 166.603 1.00 112.65 ? 291 ALA A CA  1 
ATOM   5349 C C   . ALA C 3 291 ? 172.121 106.149 165.376 1.00 117.11 ? 291 ALA A C   1 
ATOM   5350 O O   . ALA C 3 291 ? 173.033 106.914 165.051 1.00 115.89 ? 291 ALA A O   1 
ATOM   5351 C CB  . ALA C 3 291 ? 172.193 106.715 167.804 1.00 110.38 ? 291 ALA A CB  1 
ATOM   5352 N N   . GLY C 3 292 ? 171.840 105.041 164.695 1.00 123.56 ? 292 GLY A N   1 
ATOM   5353 C CA  . GLY C 3 292 ? 172.612 104.624 163.541 1.00 122.44 ? 292 GLY A CA  1 
ATOM   5354 C C   . GLY C 3 292 ? 173.790 103.748 163.907 1.00 124.27 ? 292 GLY A C   1 
ATOM   5355 O O   . GLY C 3 292 ? 173.761 102.532 163.691 1.00 125.03 ? 292 GLY A O   1 
ATOM   5356 N N   . SER C 3 293 ? 174.831 104.354 164.465 1.00 114.72 ? 293 SER A N   1 
ATOM   5357 C CA  . SER C 3 293 ? 176.003 103.623 164.927 1.00 111.42 ? 293 SER A CA  1 
ATOM   5358 C C   . SER C 3 293 ? 176.720 104.495 165.954 1.00 108.47 ? 293 SER A C   1 
ATOM   5359 O O   . SER C 3 293 ? 176.151 105.469 166.460 1.00 110.22 ? 293 SER A O   1 
ATOM   5360 C CB  . SER C 3 293 ? 176.900 103.226 163.744 1.00 110.27 ? 293 SER A CB  1 
ATOM   5361 O OG  . SER C 3 293 ? 176.240 102.310 162.892 1.00 108.03 ? 293 SER A OG  1 
ATOM   5362 N N   . ASN C 3 294 ? 177.965 104.147 166.262 1.00 106.00 ? 294 ASN A N   1 
ATOM   5363 C CA  . ASN C 3 294 ? 178.751 104.835 167.278 1.00 108.24 ? 294 ASN A CA  1 
ATOM   5364 C C   . ASN C 3 294 ? 179.857 105.681 166.654 1.00 110.67 ? 294 ASN A C   1 
ATOM   5365 O O   . ASN C 3 294 ? 180.985 105.717 167.147 1.00 113.13 ? 294 ASN A O   1 
ATOM   5366 C CB  . ASN C 3 294 ? 179.336 103.836 168.271 1.00 110.68 ? 294 ASN A CB  1 
ATOM   5367 C CG  . ASN C 3 294 ? 178.272 103.173 169.122 1.00 109.58 ? 294 ASN A CG  1 
ATOM   5368 O OD1 . ASN C 3 294 ? 178.050 103.558 170.268 1.00 110.24 ? 294 ASN A OD1 1 
ATOM   5369 N ND2 . ASN C 3 294 ? 177.610 102.167 168.564 1.00 110.03 ? 294 ASN A ND2 1 
ATOM   5370 N N   . THR C 3 295 ? 179.548 106.359 165.554 1.00 105.82 ? 295 THR A N   1 
ATOM   5371 C CA  . THR C 3 295 ? 180.467 107.302 164.938 1.00 106.02 ? 295 THR A CA  1 
ATOM   5372 C C   . THR C 3 295 ? 179.977 108.728 165.158 1.00 107.21 ? 295 THR A C   1 
ATOM   5373 O O   . THR C 3 295 ? 178.791 108.975 165.390 1.00 108.90 ? 295 THR A O   1 
ATOM   5374 C CB  . THR C 3 295 ? 180.630 107.031 163.439 1.00 107.01 ? 295 THR A CB  1 
ATOM   5375 O OG1 . THR C 3 295 ? 181.261 108.157 162.815 1.00 107.37 ? 295 THR A OG1 1 
ATOM   5376 C CG2 . THR C 3 295 ? 179.282 106.797 162.793 1.00 107.35 ? 295 THR A CG2 1 
ATOM   5377 N N   . TYR C 3 296 ? 180.920 109.668 165.085 1.00 104.33 ? 296 TYR A N   1 
ATOM   5378 C CA  . TYR C 3 296 ? 180.612 111.065 165.378 1.00 105.52 ? 296 TYR A CA  1 
ATOM   5379 C C   . TYR C 3 296 ? 179.613 111.643 164.383 1.00 110.08 ? 296 TYR A C   1 
ATOM   5380 O O   . TYR C 3 296 ? 178.740 112.436 164.760 1.00 109.24 ? 296 TYR A O   1 
ATOM   5381 C CB  . TYR C 3 296 ? 181.903 111.883 165.385 1.00 103.68 ? 296 TYR A CB  1 
ATOM   5382 C CG  . TYR C 3 296 ? 181.702 113.379 165.320 1.00 103.50 ? 296 TYR A CG  1 
ATOM   5383 C CD1 . TYR C 3 296 ? 181.138 114.072 166.382 1.00 104.64 ? 296 TYR A CD1 1 
ATOM   5384 C CD2 . TYR C 3 296 ? 182.092 114.101 164.201 1.00 103.80 ? 296 TYR A CD2 1 
ATOM   5385 C CE1 . TYR C 3 296 ? 180.958 115.440 166.326 1.00 105.98 ? 296 TYR A CE1 1 
ATOM   5386 C CE2 . TYR C 3 296 ? 181.916 115.469 164.137 1.00 105.23 ? 296 TYR A CE2 1 
ATOM   5387 C CZ  . TYR C 3 296 ? 181.349 116.132 165.202 1.00 107.03 ? 296 TYR A CZ  1 
ATOM   5388 O OH  . TYR C 3 296 ? 181.172 117.495 165.141 1.00 108.52 ? 296 TYR A OH  1 
ATOM   5389 N N   . GLU C 3 297 ? 179.720 111.251 163.111 1.00 118.19 ? 297 GLU A N   1 
ATOM   5390 C CA  . GLU C 3 297 ? 178.945 111.892 162.051 1.00 114.58 ? 297 GLU A CA  1 
ATOM   5391 C C   . GLU C 3 297 ? 177.446 111.782 162.303 1.00 112.36 ? 297 GLU A C   1 
ATOM   5392 O O   . GLU C 3 297 ? 176.762 112.791 162.516 1.00 115.36 ? 297 GLU A O   1 
ATOM   5393 C CB  . GLU C 3 297 ? 179.308 111.276 160.699 1.00 113.75 ? 297 GLU A CB  1 
ATOM   5394 C CG  . GLU C 3 297 ? 179.310 112.266 159.549 1.00 115.45 ? 297 GLU A CG  1 
ATOM   5395 C CD  . GLU C 3 297 ? 177.961 112.360 158.863 1.00 117.68 ? 297 GLU A CD  1 
ATOM   5396 O OE1 . GLU C 3 297 ? 177.241 111.340 158.825 1.00 118.87 ? 297 GLU A OE1 1 
ATOM   5397 O OE2 . GLU C 3 297 ? 177.622 113.452 158.362 1.00 116.41 ? 297 GLU A OE2 1 
ATOM   5398 N N   . GLU C 3 298 ? 176.913 110.559 162.288 1.00 97.77  ? 298 GLU A N   1 
ATOM   5399 C CA  . GLU C 3 298 ? 175.466 110.417 162.390 1.00 103.73 ? 298 GLU A CA  1 
ATOM   5400 C C   . GLU C 3 298 ? 174.969 110.698 163.799 1.00 106.07 ? 298 GLU A C   1 
ATOM   5401 O O   . GLU C 3 298 ? 173.814 111.099 163.971 1.00 112.44 ? 298 GLU A O   1 
ATOM   5402 C CB  . GLU C 3 298 ? 175.023 109.031 161.925 1.00 106.73 ? 298 GLU A CB  1 
ATOM   5403 C CG  . GLU C 3 298 ? 175.911 107.888 162.353 1.00 107.48 ? 298 GLU A CG  1 
ATOM   5404 C CD  . GLU C 3 298 ? 175.667 106.643 161.524 1.00 106.27 ? 298 GLU A CD  1 
ATOM   5405 O OE1 . GLU C 3 298 ? 175.491 106.771 160.295 1.00 105.47 ? 298 GLU A OE1 1 
ATOM   5406 O OE2 . GLU C 3 298 ? 175.634 105.538 162.100 1.00 101.24 ? 298 GLU A OE2 1 
ATOM   5407 N N   . ALA C 3 299 ? 175.817 110.524 164.814 1.00 84.45  ? 299 ALA A N   1 
ATOM   5408 C CA  . ALA C 3 299 ? 175.424 110.923 166.161 1.00 88.29  ? 299 ALA A CA  1 
ATOM   5409 C C   . ALA C 3 299 ? 175.152 112.422 166.224 1.00 88.92  ? 299 ALA A C   1 
ATOM   5410 O O   . ALA C 3 299 ? 174.086 112.858 166.682 1.00 89.59  ? 299 ALA A O   1 
ATOM   5411 C CB  . ALA C 3 299 ? 176.508 110.527 167.162 1.00 87.70  ? 299 ALA A CB  1 
ATOM   5412 N N   . ALA C 3 300 ? 176.102 113.225 165.740 1.00 86.56  ? 300 ALA A N   1 
ATOM   5413 C CA  . ALA C 3 300 ? 175.905 114.669 165.716 1.00 89.55  ? 300 ALA A CA  1 
ATOM   5414 C C   . ALA C 3 300 ? 174.733 115.047 164.823 1.00 87.85  ? 300 ALA A C   1 
ATOM   5415 O O   . ALA C 3 300 ? 173.973 115.970 165.140 1.00 91.72  ? 300 ALA A O   1 
ATOM   5416 C CB  . ALA C 3 300 ? 177.184 115.366 165.252 1.00 92.42  ? 300 ALA A CB  1 
ATOM   5417 N N   . ALA C 3 301 ? 174.575 114.349 163.696 1.00 85.82  ? 301 ALA A N   1 
ATOM   5418 C CA  . ALA C 3 301 ? 173.457 114.639 162.805 1.00 88.28  ? 301 ALA A CA  1 
ATOM   5419 C C   . ALA C 3 301 ? 172.122 114.412 163.503 1.00 86.64  ? 301 ALA A C   1 
ATOM   5420 O O   . ALA C 3 301 ? 171.208 115.237 163.393 1.00 91.81  ? 301 ALA A O   1 
ATOM   5421 C CB  . ALA C 3 301 ? 173.556 113.785 161.542 1.00 89.97  ? 301 ALA A CB  1 
ATOM   5422 N N   . TYR C 3 302 ? 171.993 113.300 164.230 1.00 82.50  ? 302 TYR A N   1 
ATOM   5423 C CA  . TYR C 3 302 ? 170.753 113.024 164.943 1.00 89.12  ? 302 TYR A CA  1 
ATOM   5424 C C   . TYR C 3 302 ? 170.505 114.052 166.036 1.00 92.89  ? 302 TYR A C   1 
ATOM   5425 O O   . TYR C 3 302 ? 169.369 114.500 166.224 1.00 95.62  ? 302 TYR A O   1 
ATOM   5426 C CB  . TYR C 3 302 ? 170.782 111.614 165.530 1.00 91.86  ? 302 TYR A CB  1 
ATOM   5427 C CG  . TYR C 3 302 ? 169.440 111.148 166.048 1.00 88.44  ? 302 TYR A CG  1 
ATOM   5428 C CD1 . TYR C 3 302 ? 168.316 111.176 165.237 1.00 86.63  ? 302 TYR A CD1 1 
ATOM   5429 C CD2 . TYR C 3 302 ? 169.299 110.683 167.346 1.00 84.68  ? 302 TYR A CD2 1 
ATOM   5430 C CE1 . TYR C 3 302 ? 167.093 110.753 165.704 1.00 87.02  ? 302 TYR A CE1 1 
ATOM   5431 C CE2 . TYR C 3 302 ? 168.080 110.260 167.821 1.00 84.45  ? 302 TYR A CE2 1 
ATOM   5432 C CZ  . TYR C 3 302 ? 166.981 110.296 166.996 1.00 89.07  ? 302 TYR A CZ  1 
ATOM   5433 O OH  . TYR C 3 302 ? 165.760 109.873 167.467 1.00 96.53  ? 302 TYR A OH  1 
ATOM   5434 N N   . ILE C 3 303 ? 171.554 114.442 166.766 1.00 82.99  ? 303 ILE A N   1 
ATOM   5435 C CA  . ILE C 3 303 ? 171.378 115.443 167.818 1.00 77.97  ? 303 ILE A CA  1 
ATOM   5436 C C   . ILE C 3 303 ? 170.891 116.759 167.224 1.00 78.17  ? 303 ILE A C   1 
ATOM   5437 O O   . ILE C 3 303 ? 169.946 117.382 167.728 1.00 78.53  ? 303 ILE A O   1 
ATOM   5438 C CB  . ILE C 3 303 ? 172.685 115.639 168.605 1.00 75.59  ? 303 ILE A CB  1 
ATOM   5439 C CG1 . ILE C 3 303 ? 173.146 114.322 169.228 1.00 79.02  ? 303 ILE A CG1 1 
ATOM   5440 C CG2 . ILE C 3 303 ? 172.501 116.715 169.647 1.00 75.46  ? 303 ILE A CG2 1 
ATOM   5441 C CD1 . ILE C 3 303 ? 172.566 114.046 170.581 1.00 79.06  ? 303 ILE A CD1 1 
ATOM   5442 N N   . GLN C 3 304 ? 171.528 117.198 166.138 1.00 91.70  ? 304 GLN A N   1 
ATOM   5443 C CA  . GLN C 3 304 ? 171.152 118.461 165.516 1.00 91.14  ? 304 GLN A CA  1 
ATOM   5444 C C   . GLN C 3 304 ? 169.739 118.402 164.950 1.00 90.09  ? 304 GLN A C   1 
ATOM   5445 O O   . GLN C 3 304 ? 168.974 119.366 165.075 1.00 93.36  ? 304 GLN A O   1 
ATOM   5446 C CB  . GLN C 3 304 ? 172.165 118.821 164.431 1.00 91.27  ? 304 GLN A CB  1 
ATOM   5447 C CG  . GLN C 3 304 ? 171.794 120.020 163.587 1.00 90.25  ? 304 GLN A CG  1 
ATOM   5448 C CD  . GLN C 3 304 ? 172.550 120.052 162.275 1.00 94.45  ? 304 GLN A CD  1 
ATOM   5449 O OE1 . GLN C 3 304 ? 172.279 119.263 161.370 1.00 97.44  ? 304 GLN A OE1 1 
ATOM   5450 N NE2 . GLN C 3 304 ? 173.515 120.957 162.171 1.00 93.10  ? 304 GLN A NE2 1 
ATOM   5451 N N   . CYS C 3 305 ? 169.370 117.279 164.329 1.00 97.99  ? 305 CYS A N   1 
ATOM   5452 C CA  . CYS C 3 305 ? 168.021 117.143 163.791 1.00 98.96  ? 305 CYS A CA  1 
ATOM   5453 C C   . CYS C 3 305 ? 166.981 117.152 164.903 1.00 96.28  ? 305 CYS A C   1 
ATOM   5454 O O   . CYS C 3 305 ? 165.904 117.741 164.750 1.00 98.91  ? 305 CYS A O   1 
ATOM   5455 C CB  . CYS C 3 305 ? 167.911 115.863 162.964 1.00 102.08 ? 305 CYS A CB  1 
ATOM   5456 S SG  . CYS C 3 305 ? 166.569 115.873 161.752 1.00 111.62 ? 305 CYS A SG  1 
ATOM   5457 N N   . GLN C 3 306 ? 167.281 116.502 166.028 1.00 83.24  ? 306 GLN A N   1 
ATOM   5458 C CA  . GLN C 3 306 ? 166.319 116.455 167.122 1.00 87.62  ? 306 GLN A CA  1 
ATOM   5459 C C   . GLN C 3 306 ? 166.188 117.803 167.816 1.00 89.41  ? 306 GLN A C   1 
ATOM   5460 O O   . GLN C 3 306 ? 165.117 118.122 168.341 1.00 90.51  ? 306 GLN A O   1 
ATOM   5461 C CB  . GLN C 3 306 ? 166.716 115.372 168.122 1.00 89.76  ? 306 GLN A CB  1 
ATOM   5462 C CG  . GLN C 3 306 ? 165.816 114.151 168.084 1.00 89.81  ? 306 GLN A CG  1 
ATOM   5463 C CD  . GLN C 3 306 ? 164.633 114.272 169.019 1.00 93.52  ? 306 GLN A CD  1 
ATOM   5464 O OE1 . GLN C 3 306 ? 164.267 115.370 169.436 1.00 96.23  ? 306 GLN A OE1 1 
ATOM   5465 N NE2 . GLN C 3 306 ? 164.025 113.140 169.353 1.00 92.08  ? 306 GLN A NE2 1 
ATOM   5466 N N   . PHE C 3 307 ? 167.258 118.599 167.847 1.00 85.41  ? 307 PHE A N   1 
ATOM   5467 C CA  . PHE C 3 307 ? 167.136 119.942 168.409 1.00 81.30  ? 307 PHE A CA  1 
ATOM   5468 C C   . PHE C 3 307 ? 166.434 120.904 167.458 1.00 84.79  ? 307 PHE A C   1 
ATOM   5469 O O   . PHE C 3 307 ? 165.664 121.762 167.902 1.00 86.78  ? 307 PHE A O   1 
ATOM   5470 C CB  . PHE C 3 307 ? 168.509 120.493 168.789 1.00 79.00  ? 307 PHE A CB  1 
ATOM   5471 C CG  . PHE C 3 307 ? 168.853 120.317 170.238 1.00 78.99  ? 307 PHE A CG  1 
ATOM   5472 C CD1 . PHE C 3 307 ? 168.057 120.878 171.218 1.00 77.38  ? 307 PHE A CD1 1 
ATOM   5473 C CD2 . PHE C 3 307 ? 169.975 119.608 170.619 1.00 86.30  ? 307 PHE A CD2 1 
ATOM   5474 C CE1 . PHE C 3 307 ? 168.366 120.728 172.549 1.00 80.51  ? 307 PHE A CE1 1 
ATOM   5475 C CE2 . PHE C 3 307 ? 170.290 119.455 171.951 1.00 85.73  ? 307 PHE A CE2 1 
ATOM   5476 C CZ  . PHE C 3 307 ? 169.484 120.016 172.917 1.00 82.90  ? 307 PHE A CZ  1 
ATOM   5477 N N   . GLU C 3 308 ? 166.678 120.780 166.154 1.00 91.24  ? 308 GLU A N   1 
ATOM   5478 C CA  . GLU C 3 308 ? 166.196 121.770 165.198 1.00 87.17  ? 308 GLU A CA  1 
ATOM   5479 C C   . GLU C 3 308 ? 164.705 121.664 164.905 1.00 85.36  ? 308 GLU A C   1 
ATOM   5480 O O   . GLU C 3 308 ? 164.163 122.555 164.244 1.00 87.14  ? 308 GLU A O   1 
ATOM   5481 C CB  . GLU C 3 308 ? 166.975 121.657 163.886 1.00 88.75  ? 308 GLU A CB  1 
ATOM   5482 C CG  . GLU C 3 308 ? 167.992 122.764 163.671 1.00 88.34  ? 308 GLU A CG  1 
ATOM   5483 C CD  . GLU C 3 308 ? 168.625 122.714 162.294 1.00 92.24  ? 308 GLU A CD  1 
ATOM   5484 O OE1 . GLU C 3 308 ? 168.995 121.608 161.849 1.00 93.46  ? 308 GLU A OE1 1 
ATOM   5485 O OE2 . GLU C 3 308 ? 168.753 123.781 161.657 1.00 90.86  ? 308 GLU A OE2 1 
ATOM   5486 N N   . ASP C 3 309 ? 164.028 120.612 165.362 1.00 81.85  ? 309 ASP A N   1 
ATOM   5487 C CA  . ASP C 3 309 ? 162.611 120.433 165.072 1.00 86.66  ? 309 ASP A CA  1 
ATOM   5488 C C   . ASP C 3 309 ? 161.721 120.659 166.288 1.00 88.70  ? 309 ASP A C   1 
ATOM   5489 O O   . ASP C 3 309 ? 160.520 120.375 166.225 1.00 92.25  ? 309 ASP A O   1 
ATOM   5490 C CB  . ASP C 3 309 ? 162.360 119.044 164.477 1.00 89.43  ? 309 ASP A CB  1 
ATOM   5491 C CG  . ASP C 3 309 ? 162.340 117.948 165.522 1.00 92.14  ? 309 ASP A CG  1 
ATOM   5492 O OD1 . ASP C 3 309 ? 163.032 118.084 166.552 1.00 89.55  ? 309 ASP A OD1 1 
ATOM   5493 O OD2 . ASP C 3 309 ? 161.627 116.945 165.312 1.00 93.99  ? 309 ASP A OD2 1 
ATOM   5494 N N   . LEU C 3 310 ? 162.276 121.163 167.392 1.00 81.21  ? 310 LEU A N   1 
ATOM   5495 C CA  . LEU C 3 310 ? 161.447 121.468 168.554 1.00 81.52  ? 310 LEU A CA  1 
ATOM   5496 C C   . LEU C 3 310 ? 160.530 122.656 168.296 1.00 82.18  ? 310 LEU A C   1 
ATOM   5497 O O   . LEU C 3 310 ? 159.432 122.723 168.860 1.00 84.57  ? 310 LEU A O   1 
ATOM   5498 C CB  . LEU C 3 310 ? 162.326 121.732 169.775 1.00 83.03  ? 310 LEU A CB  1 
ATOM   5499 C CG  . LEU C 3 310 ? 162.494 120.587 170.776 1.00 85.24  ? 310 LEU A CG  1 
ATOM   5500 C CD1 . LEU C 3 310 ? 161.301 120.522 171.713 1.00 84.83  ? 310 LEU A CD1 1 
ATOM   5501 C CD2 . LEU C 3 310 ? 162.682 119.262 170.064 1.00 84.29  ? 310 LEU A CD2 1 
ATOM   5502 N N   . ASN C 3 311 ? 160.954 123.595 167.456 1.00 88.14  ? 311 ASN A N   1 
ATOM   5503 C CA  . ASN C 3 311 ? 160.150 124.777 167.185 1.00 88.56  ? 311 ASN A CA  1 
ATOM   5504 C C   . ASN C 3 311 ? 158.954 124.430 166.308 1.00 88.53  ? 311 ASN A C   1 
ATOM   5505 O O   . ASN C 3 311 ? 158.968 123.454 165.554 1.00 93.48  ? 311 ASN A O   1 
ATOM   5506 C CB  . ASN C 3 311 ? 160.997 125.855 166.512 1.00 88.46  ? 311 ASN A CB  1 
ATOM   5507 C CG  . ASN C 3 311 ? 161.304 125.534 165.066 1.00 91.25  ? 311 ASN A CG  1 
ATOM   5508 O OD1 . ASN C 3 311 ? 161.610 124.393 164.722 1.00 93.86  ? 311 ASN A OD1 1 
ATOM   5509 N ND2 . ASN C 3 311 ? 161.228 126.544 164.208 1.00 89.83  ? 311 ASN A ND2 1 
ATOM   5510 N N   . LYS C 3 312 ? 157.909 125.247 166.415 1.00 82.41  ? 312 LYS A N   1 
ATOM   5511 C CA  . LYS C 3 312 ? 156.676 125.032 165.671 1.00 85.95  ? 312 LYS A CA  1 
ATOM   5512 C C   . LYS C 3 312 ? 156.458 126.031 164.548 1.00 89.99  ? 312 LYS A C   1 
ATOM   5513 O O   . LYS C 3 312 ? 155.878 125.669 163.523 1.00 94.11  ? 312 LYS A O   1 
ATOM   5514 C CB  . LYS C 3 312 ? 155.469 125.082 166.616 1.00 86.53  ? 312 LYS A CB  1 
ATOM   5515 C CG  . LYS C 3 312 ? 155.175 123.766 167.310 1.00 88.14  ? 312 LYS A CG  1 
ATOM   5516 C CD  . LYS C 3 312 ? 154.601 123.990 168.698 1.00 88.90  ? 312 LYS A CD  1 
ATOM   5517 C CE  . LYS C 3 312 ? 154.781 122.763 169.576 1.00 88.27  ? 312 LYS A CE  1 
ATOM   5518 N NZ  . LYS C 3 312 ? 153.812 122.742 170.705 1.00 90.90  ? 312 LYS A NZ  1 
ATOM   5519 N N   . ARG C 3 313 ? 156.906 127.276 164.714 1.00 96.56  ? 313 ARG A N   1 
ATOM   5520 C CA  . ARG C 3 313 ? 156.760 128.298 163.680 1.00 99.16  ? 313 ARG A CA  1 
ATOM   5521 C C   . ARG C 3 313 ? 158.004 128.267 162.797 1.00 100.23 ? 313 ARG A C   1 
ATOM   5522 O O   . ARG C 3 313 ? 158.935 129.061 162.940 1.00 99.81  ? 313 ARG A O   1 
ATOM   5523 C CB  . ARG C 3 313 ? 156.539 129.667 164.309 1.00 97.73  ? 313 ARG A CB  1 
ATOM   5524 C CG  . ARG C 3 313 ? 155.509 129.664 165.425 1.00 98.67  ? 313 ARG A CG  1 
ATOM   5525 C CD  . ARG C 3 313 ? 155.335 131.047 166.023 1.00 100.24 ? 313 ARG A CD  1 
ATOM   5526 N NE  . ARG C 3 313 ? 154.398 131.039 167.139 1.00 101.20 ? 313 ARG A NE  1 
ATOM   5527 C CZ  . ARG C 3 313 ? 154.739 130.807 168.399 1.00 100.34 ? 313 ARG A CZ  1 
ATOM   5528 N NH1 . ARG C 3 313 ? 155.991 130.557 168.742 1.00 98.59  ? 313 ARG A NH1 1 
ATOM   5529 N NH2 . ARG C 3 313 ? 153.798 130.825 169.339 1.00 98.61  ? 313 ARG A NH2 1 
ATOM   5530 N N   . LYS C 3 314 ? 158.009 127.317 161.861 1.00 103.22 ? 314 LYS A N   1 
ATOM   5531 C CA  . LYS C 3 314 ? 159.162 127.107 160.994 1.00 102.84 ? 314 LYS A CA  1 
ATOM   5532 C C   . LYS C 3 314 ? 159.339 128.210 159.959 1.00 103.08 ? 314 LYS A C   1 
ATOM   5533 O O   . LYS C 3 314 ? 160.376 128.242 159.289 1.00 105.11 ? 314 LYS A O   1 
ATOM   5534 C CB  . LYS C 3 314 ? 159.043 125.755 160.290 1.00 101.31 ? 314 LYS A CB  1 
ATOM   5535 C CG  . LYS C 3 314 ? 159.124 124.563 161.226 1.00 103.27 ? 314 LYS A CG  1 
ATOM   5536 C CD  . LYS C 3 314 ? 160.077 123.506 160.698 1.00 102.87 ? 314 LYS A CD  1 
ATOM   5537 C CE  . LYS C 3 314 ? 160.024 122.247 161.546 1.00 102.75 ? 314 LYS A CE  1 
ATOM   5538 N NZ  . LYS C 3 314 ? 158.629 121.888 161.915 1.00 104.89 ? 314 LYS A NZ  1 
ATOM   5539 N N   . ASP C 3 315 ? 158.365 129.104 159.809 1.00 103.17 ? 315 ASP A N   1 
ATOM   5540 C CA  . ASP C 3 315 ? 158.431 130.173 158.820 1.00 102.70 ? 315 ASP A CA  1 
ATOM   5541 C C   . ASP C 3 315 ? 158.900 131.499 159.400 1.00 104.81 ? 315 ASP A C   1 
ATOM   5542 O O   . ASP C 3 315 ? 159.626 132.239 158.729 1.00 104.77 ? 315 ASP A O   1 
ATOM   5543 C CB  . ASP C 3 315 ? 157.062 130.365 158.163 1.00 102.03 ? 315 ASP A CB  1 
ATOM   5544 C CG  . ASP C 3 315 ? 155.934 130.411 159.173 1.00 104.57 ? 315 ASP A CG  1 
ATOM   5545 O OD1 . ASP C 3 315 ? 156.190 130.128 160.361 1.00 106.27 ? 315 ASP A OD1 1 
ATOM   5546 O OD2 . ASP C 3 315 ? 154.793 130.730 158.779 1.00 102.88 ? 315 ASP A OD2 1 
ATOM   5547 N N   . THR C 3 316 ? 158.503 131.821 160.632 1.00 103.15 ? 316 THR A N   1 
ATOM   5548 C CA  . THR C 3 316 ? 158.815 133.117 161.219 1.00 101.82 ? 316 THR A CA  1 
ATOM   5549 C C   . THR C 3 316 ? 160.199 133.180 161.853 1.00 99.93  ? 316 THR A C   1 
ATOM   5550 O O   . THR C 3 316 ? 160.660 134.281 162.172 1.00 99.96  ? 316 THR A O   1 
ATOM   5551 C CB  . THR C 3 316 ? 157.764 133.486 162.268 1.00 101.92 ? 316 THR A CB  1 
ATOM   5552 O OG1 . THR C 3 316 ? 158.054 132.808 163.497 1.00 102.94 ? 316 THR A OG1 1 
ATOM   5553 C CG2 . THR C 3 316 ? 156.376 133.090 161.792 1.00 98.99  ? 316 THR A CG2 1 
ATOM   5554 N N   . LYS C 3 317 ? 160.871 132.048 162.044 1.00 80.04  ? 317 LYS A N   1 
ATOM   5555 C CA  . LYS C 3 317 ? 162.179 132.052 162.680 1.00 76.61  ? 317 LYS A CA  1 
ATOM   5556 C C   . LYS C 3 317 ? 163.014 130.908 162.128 1.00 78.47  ? 317 LYS A C   1 
ATOM   5557 O O   . LYS C 3 317 ? 162.493 129.963 161.530 1.00 80.11  ? 317 LYS A O   1 
ATOM   5558 C CB  . LYS C 3 317 ? 162.060 131.956 164.205 1.00 79.89  ? 317 LYS A CB  1 
ATOM   5559 C CG  . LYS C 3 317 ? 161.804 130.558 164.730 1.00 82.43  ? 317 LYS A CG  1 
ATOM   5560 C CD  . LYS C 3 317 ? 161.886 130.518 166.247 1.00 81.68  ? 317 LYS A CD  1 
ATOM   5561 C CE  . LYS C 3 317 ? 161.071 131.633 166.881 1.00 80.44  ? 317 LYS A CE  1 
ATOM   5562 N NZ  . LYS C 3 317 ? 159.633 131.557 166.506 1.00 80.53  ? 317 LYS A NZ  1 
ATOM   5563 N N   . GLU C 3 318 ? 164.326 131.008 162.333 1.00 76.01  ? 318 GLU A N   1 
ATOM   5564 C CA  . GLU C 3 318 ? 165.269 130.034 161.806 1.00 74.55  ? 318 GLU A CA  1 
ATOM   5565 C C   . GLU C 3 318 ? 166.325 129.726 162.858 1.00 75.26  ? 318 GLU A C   1 
ATOM   5566 O O   . GLU C 3 318 ? 166.585 130.523 163.762 1.00 80.57  ? 318 GLU A O   1 
ATOM   5567 C CB  . GLU C 3 318 ? 165.928 130.542 160.517 1.00 72.05  ? 318 GLU A CB  1 
ATOM   5568 C CG  . GLU C 3 318 ? 166.253 129.453 159.514 1.00 79.43  ? 318 GLU A CG  1 
ATOM   5569 C CD  . GLU C 3 318 ? 166.489 130.000 158.121 1.00 83.29  ? 318 GLU A CD  1 
ATOM   5570 O OE1 . GLU C 3 318 ? 166.246 131.206 157.907 1.00 77.62  ? 318 GLU A OE1 1 
ATOM   5571 O OE2 . GLU C 3 318 ? 166.918 129.225 157.241 1.00 83.97  ? 318 GLU A OE2 1 
ATOM   5572 N N   . ILE C 3 319 ? 166.934 128.550 162.726 1.00 51.52  ? 319 ILE A N   1 
ATOM   5573 C CA  . ILE C 3 319 ? 167.972 128.070 163.631 1.00 48.08  ? 319 ILE A CA  1 
ATOM   5574 C C   . ILE C 3 319 ? 169.217 127.784 162.805 1.00 56.32  ? 319 ILE A C   1 
ATOM   5575 O O   . ILE C 3 319 ? 169.127 127.167 161.738 1.00 64.10  ? 319 ILE A O   1 
ATOM   5576 C CB  . ILE C 3 319 ? 167.523 126.817 164.407 1.00 51.04  ? 319 ILE A CB  1 
ATOM   5577 C CG1 . ILE C 3 319 ? 166.425 127.159 165.418 1.00 57.34  ? 319 ILE A CG1 1 
ATOM   5578 C CG2 . ILE C 3 319 ? 168.700 126.165 165.108 1.00 56.44  ? 319 ILE A CG2 1 
ATOM   5579 C CD1 . ILE C 3 319 ? 165.018 127.141 164.857 1.00 58.55  ? 319 ILE A CD1 1 
ATOM   5580 N N   . TYR C 3 320 ? 170.383 128.198 163.326 1.00 58.33  ? 320 TYR A N   1 
ATOM   5581 C CA  . TYR C 3 320 ? 171.666 128.097 162.571 1.00 61.05  ? 320 TYR A CA  1 
ATOM   5582 C C   . TYR C 3 320 ? 172.470 126.825 162.891 1.00 60.19  ? 320 TYR A C   1 
ATOM   5583 O O   . TYR C 3 320 ? 173.287 126.451 162.034 1.00 59.93  ? 320 TYR A O   1 
ATOM   5584 C CB  . TYR C 3 320 ? 172.438 129.398 162.777 1.00 54.33  ? 320 TYR A CB  1 
ATOM   5585 C CG  . TYR C 3 320 ? 171.624 130.608 162.396 1.00 54.23  ? 320 TYR A CG  1 
ATOM   5586 C CD1 . TYR C 3 320 ? 171.143 130.757 161.108 1.00 56.56  ? 320 TYR A CD1 1 
ATOM   5587 C CD2 . TYR C 3 320 ? 171.295 131.578 163.327 1.00 54.89  ? 320 TYR A CD2 1 
ATOM   5588 C CE1 . TYR C 3 320 ? 170.378 131.851 160.743 1.00 53.66  ? 320 TYR A CE1 1 
ATOM   5589 C CE2 . TYR C 3 320 ? 170.526 132.676 162.982 1.00 59.25  ? 320 TYR A CE2 1 
ATOM   5590 C CZ  . TYR C 3 320 ? 170.067 132.814 161.684 1.00 58.06  ? 320 TYR A CZ  1 
ATOM   5591 O OH  . TYR C 3 320 ? 169.308 133.897 161.322 1.00 54.88  ? 320 TYR A OH  1 
ATOM   5592 N N   . THR C 3 321 ? 172.344 126.235 164.080 1.00 65.25  ? 321 THR A N   1 
ATOM   5593 C CA  . THR C 3 321 ? 172.944 124.894 164.374 1.00 63.84  ? 321 THR A CA  1 
ATOM   5594 C C   . THR C 3 321 ? 174.446 124.766 164.081 1.00 56.10  ? 321 THR A C   1 
ATOM   5595 O O   . THR C 3 321 ? 174.833 123.765 163.461 1.00 61.46  ? 321 THR A O   1 
ATOM   5596 C CB  . THR C 3 321 ? 172.140 123.750 163.741 1.00 68.21  ? 321 THR A CB  1 
ATOM   5597 O OG1 . THR C 3 321 ? 172.764 122.567 164.233 1.00 69.04  ? 321 THR A OG1 1 
ATOM   5598 C CG2 . THR C 3 321 ? 172.104 123.755 162.228 1.00 68.03  ? 321 THR A CG2 1 
ATOM   5599 N N   . HIS C 3 322 ? 175.263 125.717 164.503 1.00 63.65  ? 322 HIS A N   1 
ATOM   5600 C CA  . HIS C 3 322 ? 176.727 125.572 164.314 1.00 67.99  ? 322 HIS A CA  1 
ATOM   5601 C C   . HIS C 3 322 ? 177.416 124.716 165.381 1.00 68.23  ? 322 HIS A C   1 
ATOM   5602 O O   . HIS C 3 322 ? 176.998 124.774 166.550 1.00 72.31  ? 322 HIS A O   1 
ATOM   5603 C CB  . HIS C 3 322 ? 177.370 126.961 164.304 1.00 77.05  ? 322 HIS A CB  1 
ATOM   5604 C CG  . HIS C 3 322 ? 178.841 126.986 164.062 1.00 81.41  ? 322 HIS A CG  1 
ATOM   5605 N ND1 . HIS C 3 322 ? 179.692 127.761 164.819 1.00 75.08  ? 322 HIS A ND1 1 
ATOM   5606 C CD2 . HIS C 3 322 ? 179.608 126.365 163.160 1.00 79.11  ? 322 HIS A CD2 1 
ATOM   5607 C CE1 . HIS C 3 322 ? 180.932 127.598 164.384 1.00 74.67  ? 322 HIS A CE1 1 
ATOM   5608 N NE2 . HIS C 3 322 ? 180.904 126.755 163.377 1.00 74.77  ? 322 HIS A NE2 1 
ATOM   5609 N N   . PHE C 3 323 ? 178.436 123.943 164.991 1.00 77.59  ? 323 PHE A N   1 
ATOM   5610 C CA  . PHE C 3 323 ? 179.279 123.184 165.905 1.00 78.17  ? 323 PHE A CA  1 
ATOM   5611 C C   . PHE C 3 323 ? 180.513 123.998 166.270 1.00 83.51  ? 323 PHE A C   1 
ATOM   5612 O O   . PHE C 3 323 ? 180.973 124.841 165.496 1.00 89.82  ? 323 PHE A O   1 
ATOM   5613 C CB  . PHE C 3 323 ? 179.716 121.859 165.277 1.00 75.83  ? 323 PHE A CB  1 
ATOM   5614 C CG  . PHE C 3 323 ? 178.602 120.874 165.086 1.00 79.84  ? 323 PHE A CG  1 
ATOM   5615 C CD1 . PHE C 3 323 ? 177.739 120.984 164.011 1.00 81.40  ? 323 PHE A CD1 1 
ATOM   5616 C CD2 . PHE C 3 323 ? 178.432 119.823 165.966 1.00 79.35  ? 323 PHE A CD2 1 
ATOM   5617 C CE1 . PHE C 3 323 ? 176.720 120.073 163.831 1.00 79.37  ? 323 PHE A CE1 1 
ATOM   5618 C CE2 . PHE C 3 323 ? 177.418 118.911 165.788 1.00 77.72  ? 323 PHE A CE2 1 
ATOM   5619 C CZ  . PHE C 3 323 ? 176.561 119.037 164.720 1.00 77.72  ? 323 PHE A CZ  1 
ATOM   5620 N N   . THR C 3 324 ? 181.058 123.736 167.456 1.00 85.77  ? 324 THR A N   1 
ATOM   5621 C CA  . THR C 3 324 ? 182.233 124.467 167.907 1.00 84.76  ? 324 THR A CA  1 
ATOM   5622 C C   . THR C 3 324 ? 183.114 123.556 168.747 1.00 88.69  ? 324 THR A C   1 
ATOM   5623 O O   . THR C 3 324 ? 182.653 122.568 169.326 1.00 91.02  ? 324 THR A O   1 
ATOM   5624 C CB  . THR C 3 324 ? 181.851 125.726 168.698 1.00 84.21  ? 324 THR A CB  1 
ATOM   5625 O OG1 . THR C 3 324 ? 182.929 126.669 168.646 1.00 90.02  ? 324 THR A OG1 1 
ATOM   5626 C CG2 . THR C 3 324 ? 181.554 125.389 170.148 1.00 83.68  ? 324 THR A CG2 1 
ATOM   5627 N N   . CYS C 3 325 ? 184.399 123.897 168.792 1.00 114.90 ? 325 CYS A N   1 
ATOM   5628 C CA  . CYS C 3 325 ? 185.393 123.179 169.575 1.00 116.61 ? 325 CYS A CA  1 
ATOM   5629 C C   . CYS C 3 325 ? 186.163 124.180 170.428 1.00 117.41 ? 325 CYS A C   1 
ATOM   5630 O O   . CYS C 3 325 ? 185.904 125.387 170.397 1.00 115.92 ? 325 CYS A O   1 
ATOM   5631 C CB  . CYS C 3 325 ? 186.341 122.379 168.672 1.00 113.46 ? 325 CYS A CB  1 
ATOM   5632 S SG  . CYS C 3 325 ? 187.686 123.349 167.954 1.00 121.48 ? 325 CYS A SG  1 
ATOM   5633 N N   . SER C 3 326 ? 187.123 123.670 171.200 1.00 118.09 ? 326 SER A N   1 
ATOM   5634 C CA  . SER C 3 326 ? 187.915 124.528 172.071 1.00 116.39 ? 326 SER A CA  1 
ATOM   5635 C C   . SER C 3 326 ? 188.892 125.407 171.304 1.00 115.44 ? 326 SER A C   1 
ATOM   5636 O O   . SER C 3 326 ? 189.151 126.538 171.730 1.00 116.97 ? 326 SER A O   1 
ATOM   5637 C CB  . SER C 3 326 ? 188.680 123.682 173.091 1.00 50.00  ? 326 SER A CB  1 
ATOM   5638 O OG  . SER C 3 326 ? 189.631 122.849 172.451 1.00 50.00  ? 326 SER A OG  1 
ATOM   5639 N N   . THR C 3 327 ? 189.434 124.922 170.189 1.00 115.30 ? 327 THR A N   1 
ATOM   5640 C CA  . THR C 3 327 ? 190.433 125.655 169.425 1.00 115.77 ? 327 THR A CA  1 
ATOM   5641 C C   . THR C 3 327 ? 189.858 126.364 168.206 1.00 116.59 ? 327 THR A C   1 
ATOM   5642 O O   . THR C 3 327 ? 190.622 126.958 167.438 1.00 118.10 ? 327 THR A O   1 
ATOM   5643 C CB  . THR C 3 327 ? 191.558 124.713 168.982 1.00 115.99 ? 327 THR A CB  1 
ATOM   5644 O OG1 . THR C 3 327 ? 191.225 124.127 167.718 1.00 115.21 ? 327 THR A OG1 1 
ATOM   5645 C CG2 . THR C 3 327 ? 191.764 123.609 170.009 1.00 114.85 ? 327 THR A CG2 1 
ATOM   5646 N N   . ASP C 3 328 ? 188.544 126.316 168.004 1.00 112.33 ? 328 ASP A N   1 
ATOM   5647 C CA  . ASP C 3 328 ? 187.942 126.995 166.866 1.00 113.21 ? 328 ASP A CA  1 
ATOM   5648 C C   . ASP C 3 328 ? 188.025 128.506 167.041 1.00 113.25 ? 328 ASP A C   1 
ATOM   5649 O O   . ASP C 3 328 ? 187.824 129.033 168.138 1.00 114.76 ? 328 ASP A O   1 
ATOM   5650 C CB  . ASP C 3 328 ? 186.487 126.564 166.696 1.00 114.09 ? 328 ASP A CB  1 
ATOM   5651 C CG  . ASP C 3 328 ? 186.082 126.448 165.240 1.00 115.75 ? 328 ASP A CG  1 
ATOM   5652 O OD1 . ASP C 3 328 ? 186.690 127.141 164.397 1.00 114.32 ? 328 ASP A OD1 1 
ATOM   5653 O OD2 . ASP C 3 328 ? 185.158 125.664 164.938 1.00 114.29 ? 328 ASP A OD2 1 
ATOM   5654 N N   . THR C 3 329 ? 188.324 129.204 165.946 1.00 104.73 ? 329 THR A N   1 
ATOM   5655 C CA  . THR C 3 329 ? 188.477 130.653 165.956 1.00 106.14 ? 329 THR A CA  1 
ATOM   5656 C C   . THR C 3 329 ? 187.612 131.321 164.890 1.00 109.11 ? 329 THR A C   1 
ATOM   5657 O O   . THR C 3 329 ? 187.993 132.348 164.325 1.00 112.36 ? 329 THR A O   1 
ATOM   5658 C CB  . THR C 3 329 ? 189.945 131.040 165.776 1.00 106.64 ? 329 THR A CB  1 
ATOM   5659 O OG1 . THR C 3 329 ? 190.059 132.465 165.677 1.00 110.37 ? 329 THR A OG1 1 
ATOM   5660 C CG2 . THR C 3 329 ? 190.521 130.393 164.523 1.00 107.80 ? 329 THR A CG2 1 
ATOM   5661 N N   . LYS C 3 330 ? 186.438 130.752 164.608 1.00 95.57  ? 330 LYS A N   1 
ATOM   5662 C CA  . LYS C 3 330 ? 185.538 131.287 163.592 1.00 92.61  ? 330 LYS A CA  1 
ATOM   5663 C C   . LYS C 3 330 ? 184.112 131.455 164.105 1.00 93.77  ? 330 LYS A C   1 
ATOM   5664 O O   . LYS C 3 330 ? 183.170 131.472 163.307 1.00 99.16  ? 330 LYS A O   1 
ATOM   5665 C CB  . LYS C 3 330 ? 185.545 130.394 162.350 1.00 96.67  ? 330 LYS A CB  1 
ATOM   5666 C CG  . LYS C 3 330 ? 186.925 130.136 161.770 1.00 96.96  ? 330 LYS A CG  1 
ATOM   5667 C CD  . LYS C 3 330 ? 186.843 129.755 160.301 1.00 98.56  ? 330 LYS A CD  1 
ATOM   5668 C CE  . LYS C 3 330 ? 186.887 128.248 160.122 1.00 99.02  ? 330 LYS A CE  1 
ATOM   5669 N NZ  . LYS C 3 330 ? 188.102 127.653 160.743 1.00 98.49  ? 330 LYS A NZ  1 
ATOM   5670 N N   . ASN C 3 331 ? 183.928 131.577 165.421 1.00 88.10  ? 331 ASN A N   1 
ATOM   5671 C CA  . ASN C 3 331 ? 182.579 131.705 165.966 1.00 92.45  ? 331 ASN A CA  1 
ATOM   5672 C C   . ASN C 3 331 ? 181.997 133.088 165.694 1.00 90.54  ? 331 ASN A C   1 
ATOM   5673 O O   . ASN C 3 331 ? 180.818 133.218 165.331 1.00 91.29  ? 331 ASN A O   1 
ATOM   5674 C CB  . ASN C 3 331 ? 182.595 131.417 167.465 1.00 90.10  ? 331 ASN A CB  1 
ATOM   5675 C CG  . ASN C 3 331 ? 183.027 130.002 167.781 1.00 91.00  ? 331 ASN A CG  1 
ATOM   5676 O OD1 . ASN C 3 331 ? 182.217 129.075 167.767 1.00 98.46  ? 331 ASN A OD1 1 
ATOM   5677 N ND2 . ASN C 3 331 ? 184.310 129.827 168.068 1.00 89.47  ? 331 ASN A ND2 1 
ATOM   5678 N N   . VAL C 3 332 ? 182.810 134.133 165.866 1.00 79.37  ? 332 VAL A N   1 
ATOM   5679 C CA  . VAL C 3 332 ? 182.328 135.494 165.666 1.00 81.40  ? 332 VAL A CA  1 
ATOM   5680 C C   . VAL C 3 332 ? 181.916 135.712 164.217 1.00 87.92  ? 332 VAL A C   1 
ATOM   5681 O O   . VAL C 3 332 ? 180.972 136.459 163.940 1.00 86.95  ? 332 VAL A O   1 
ATOM   5682 C CB  . VAL C 3 332 ? 183.395 136.509 166.126 1.00 84.79  ? 332 VAL A CB  1 
ATOM   5683 C CG1 . VAL C 3 332 ? 184.676 136.357 165.318 1.00 87.70  ? 332 VAL A CG1 1 
ATOM   5684 C CG2 . VAL C 3 332 ? 182.859 137.930 166.039 1.00 89.58  ? 332 VAL A CG2 1 
ATOM   5685 N N   . GLN C 3 333 ? 182.599 135.059 163.273 1.00 86.15  ? 333 GLN A N   1 
ATOM   5686 C CA  . GLN C 3 333 ? 182.196 135.150 161.873 1.00 80.37  ? 333 GLN A CA  1 
ATOM   5687 C C   . GLN C 3 333 ? 180.805 134.564 161.662 1.00 77.82  ? 333 GLN A C   1 
ATOM   5688 O O   . GLN C 3 333 ? 179.984 135.134 160.930 1.00 84.62  ? 333 GLN A O   1 
ATOM   5689 C CB  . GLN C 3 333 ? 183.220 134.437 160.991 1.00 78.27  ? 333 GLN A CB  1 
ATOM   5690 C CG  . GLN C 3 333 ? 182.876 134.425 159.516 1.00 80.96  ? 333 GLN A CG  1 
ATOM   5691 C CD  . GLN C 3 333 ? 183.039 135.783 158.872 1.00 83.74  ? 333 GLN A CD  1 
ATOM   5692 O OE1 . GLN C 3 333 ? 183.933 136.548 159.232 1.00 86.94  ? 333 GLN A OE1 1 
ATOM   5693 N NE2 . GLN C 3 333 ? 182.177 136.091 157.911 1.00 83.19  ? 333 GLN A NE2 1 
ATOM   5694 N N   . PHE C 3 334 ? 180.523 133.424 162.294 1.00 61.96  ? 334 PHE A N   1 
ATOM   5695 C CA  . PHE C 3 334 ? 179.199 132.822 162.184 1.00 63.39  ? 334 PHE A CA  1 
ATOM   5696 C C   . PHE C 3 334 ? 178.133 133.729 162.785 1.00 75.27  ? 334 PHE A C   1 
ATOM   5697 O O   . PHE C 3 334 ? 177.048 133.897 162.209 1.00 84.70  ? 334 PHE A O   1 
ATOM   5698 C CB  . PHE C 3 334 ? 179.195 131.456 162.865 1.00 65.73  ? 334 PHE A CB  1 
ATOM   5699 C CG  . PHE C 3 334 ? 178.000 130.614 162.535 1.00 66.54  ? 334 PHE A CG  1 
ATOM   5700 C CD1 . PHE C 3 334 ? 176.821 130.751 163.240 1.00 69.18  ? 334 PHE A CD1 1 
ATOM   5701 C CD2 . PHE C 3 334 ? 178.060 129.679 161.519 1.00 68.32  ? 334 PHE A CD2 1 
ATOM   5702 C CE1 . PHE C 3 334 ? 175.726 129.977 162.937 1.00 69.80  ? 334 PHE A CE1 1 
ATOM   5703 C CE2 . PHE C 3 334 ? 176.966 128.901 161.212 1.00 68.85  ? 334 PHE A CE2 1 
ATOM   5704 C CZ  . PHE C 3 334 ? 175.797 129.050 161.921 1.00 70.89  ? 334 PHE A CZ  1 
ATOM   5705 N N   . VAL C 3 335 ? 178.423 134.321 163.946 1.00 75.17  ? 335 VAL A N   1 
ATOM   5706 C CA  . VAL C 3 335 ? 177.459 135.228 164.565 1.00 73.19  ? 335 VAL A CA  1 
ATOM   5707 C C   . VAL C 3 335 ? 177.223 136.440 163.671 1.00 77.22  ? 335 VAL A C   1 
ATOM   5708 O O   . VAL C 3 335 ? 176.089 136.914 163.526 1.00 78.59  ? 335 VAL A O   1 
ATOM   5709 C CB  . VAL C 3 335 ? 177.931 135.640 165.970 1.00 70.21  ? 335 VAL A CB  1 
ATOM   5710 C CG1 . VAL C 3 335 ? 176.943 136.601 166.596 1.00 71.54  ? 335 VAL A CG1 1 
ATOM   5711 C CG2 . VAL C 3 335 ? 178.109 134.417 166.846 1.00 73.30  ? 335 VAL A CG2 1 
ATOM   5712 N N   . PHE C 3 336 ? 178.289 136.952 163.052 1.00 76.10  ? 336 PHE A N   1 
ATOM   5713 C CA  . PHE C 3 336 ? 178.167 138.079 162.134 1.00 72.79  ? 336 PHE A CA  1 
ATOM   5714 C C   . PHE C 3 336 ? 177.283 137.729 160.945 1.00 71.26  ? 336 PHE A C   1 
ATOM   5715 O O   . PHE C 3 336 ? 176.421 138.523 160.546 1.00 75.75  ? 336 PHE A O   1 
ATOM   5716 C CB  . PHE C 3 336 ? 179.560 138.502 161.669 1.00 72.47  ? 336 PHE A CB  1 
ATOM   5717 C CG  . PHE C 3 336 ? 179.575 139.714 160.788 1.00 73.25  ? 336 PHE A CG  1 
ATOM   5718 C CD1 . PHE C 3 336 ? 179.597 140.983 161.333 1.00 78.88  ? 336 PHE A CD1 1 
ATOM   5719 C CD2 . PHE C 3 336 ? 179.596 139.583 159.412 1.00 71.79  ? 336 PHE A CD2 1 
ATOM   5720 C CE1 . PHE C 3 336 ? 179.622 142.097 160.524 1.00 78.90  ? 336 PHE A CE1 1 
ATOM   5721 C CE2 . PHE C 3 336 ? 179.620 140.692 158.599 1.00 74.01  ? 336 PHE A CE2 1 
ATOM   5722 C CZ  . PHE C 3 336 ? 179.633 141.951 159.155 1.00 76.31  ? 336 PHE A CZ  1 
ATOM   5723 N N   . ASP C 3 337 ? 177.482 136.543 160.366 1.00 72.61  ? 337 ASP A N   1 
ATOM   5724 C CA  . ASP C 3 337 ? 176.666 136.128 159.229 1.00 71.18  ? 337 ASP A CA  1 
ATOM   5725 C C   . ASP C 3 337 ? 175.200 136.006 159.619 1.00 71.48  ? 337 ASP A C   1 
ATOM   5726 O O   . ASP C 3 337 ? 174.312 136.474 158.892 1.00 80.13  ? 337 ASP A O   1 
ATOM   5727 C CB  . ASP C 3 337 ? 177.181 134.804 158.669 1.00 71.26  ? 337 ASP A CB  1 
ATOM   5728 C CG  . ASP C 3 337 ? 178.094 134.993 157.477 1.00 78.79  ? 337 ASP A CG  1 
ATOM   5729 O OD1 . ASP C 3 337 ? 177.878 135.952 156.708 1.00 80.77  ? 337 ASP A OD1 1 
ATOM   5730 O OD2 . ASP C 3 337 ? 179.028 134.182 157.309 1.00 79.50  ? 337 ASP A OD2 1 
ATOM   5731 N N   . ALA C 3 338 ? 174.926 135.390 160.771 1.00 53.08  ? 338 ALA A N   1 
ATOM   5732 C CA  . ALA C 3 338 ? 173.543 135.262 161.218 1.00 62.77  ? 338 ALA A CA  1 
ATOM   5733 C C   . ALA C 3 338 ? 172.906 136.629 161.449 1.00 65.34  ? 338 ALA A C   1 
ATOM   5734 O O   . ALA C 3 338 ? 171.758 136.865 161.047 1.00 69.91  ? 338 ALA A O   1 
ATOM   5735 C CB  . ALA C 3 338 ? 173.479 134.416 162.488 1.00 67.85  ? 338 ALA A CB  1 
ATOM   5736 N N   . VAL C 3 339 ? 173.639 137.544 162.087 1.00 65.91  ? 339 VAL A N   1 
ATOM   5737 C CA  . VAL C 3 339 ? 173.095 138.867 162.377 1.00 68.68  ? 339 VAL A CA  1 
ATOM   5738 C C   . VAL C 3 339 ? 172.806 139.620 161.085 1.00 78.05  ? 339 VAL A C   1 
ATOM   5739 O O   . VAL C 3 339 ? 171.770 140.286 160.955 1.00 82.11  ? 339 VAL A O   1 
ATOM   5740 C CB  . VAL C 3 339 ? 174.058 139.645 163.293 1.00 72.50  ? 339 VAL A CB  1 
ATOM   5741 C CG1 . VAL C 3 339 ? 173.806 141.143 163.196 1.00 77.06  ? 339 VAL A CG1 1 
ATOM   5742 C CG2 . VAL C 3 339 ? 173.920 139.168 164.728 1.00 71.01  ? 339 VAL A CG2 1 
ATOM   5743 N N   . THR C 3 340 ? 173.712 139.523 160.108 1.00 69.76  ? 340 THR A N   1 
ATOM   5744 C CA  . THR C 3 340 ? 173.474 140.155 158.814 1.00 58.03  ? 340 THR A CA  1 
ATOM   5745 C C   . THR C 3 340 ? 172.236 139.577 158.139 1.00 67.06  ? 340 THR A C   1 
ATOM   5746 O O   . THR C 3 340 ? 171.440 140.317 157.546 1.00 74.69  ? 340 THR A O   1 
ATOM   5747 C CB  . THR C 3 340 ? 174.703 139.994 157.920 1.00 56.45  ? 340 THR A CB  1 
ATOM   5748 O OG1 . THR C 3 340 ? 175.713 140.925 158.324 1.00 64.14  ? 340 THR A OG1 1 
ATOM   5749 C CG2 . THR C 3 340 ? 174.352 140.244 156.464 1.00 61.68  ? 340 THR A CG2 1 
ATOM   5750 N N   . ASP C 3 341 ? 172.051 138.257 158.223 1.00 66.56  ? 341 ASP A N   1 
ATOM   5751 C CA  . ASP C 3 341 ? 170.868 137.641 157.626 1.00 61.12  ? 341 ASP A CA  1 
ATOM   5752 C C   . ASP C 3 341 ? 169.588 138.168 158.263 1.00 54.00  ? 341 ASP A C   1 
ATOM   5753 O O   . ASP C 3 341 ? 168.624 138.509 157.563 1.00 67.25  ? 341 ASP A O   1 
ATOM   5754 C CB  . ASP C 3 341 ? 170.946 136.121 157.757 1.00 62.77  ? 341 ASP A CB  1 
ATOM   5755 C CG  . ASP C 3 341 ? 171.477 135.456 156.506 1.00 72.90  ? 341 ASP A CG  1 
ATOM   5756 O OD1 . ASP C 3 341 ? 172.300 136.079 155.804 1.00 76.50  ? 341 ASP A OD1 1 
ATOM   5757 O OD2 . ASP C 3 341 ? 171.072 134.310 156.223 1.00 71.79  ? 341 ASP A OD2 1 
ATOM   5758 N N   . VAL C 3 342 ? 169.560 138.249 159.593 1.00 39.93  ? 342 VAL A N   1 
ATOM   5759 C CA  . VAL C 3 342 ? 168.358 138.748 160.259 1.00 45.27  ? 342 VAL A CA  1 
ATOM   5760 C C   . VAL C 3 342 ? 168.116 140.212 159.911 1.00 50.06  ? 342 VAL A C   1 
ATOM   5761 O O   . VAL C 3 342 ? 166.968 140.638 159.733 1.00 65.14  ? 342 VAL A O   1 
ATOM   5762 C CB  . VAL C 3 342 ? 168.432 138.534 161.781 1.00 60.35  ? 342 VAL A CB  1 
ATOM   5763 C CG1 . VAL C 3 342 ? 167.055 138.699 162.391 1.00 58.68  ? 342 VAL A CG1 1 
ATOM   5764 C CG2 . VAL C 3 342 ? 168.941 137.148 162.093 1.00 63.04  ? 342 VAL A CG2 1 
ATOM   5765 N N   . ILE C 3 343 ? 169.184 141.007 159.817 1.00 52.83  ? 343 ILE A N   1 
ATOM   5766 C CA  . ILE C 3 343 ? 169.028 142.415 159.461 1.00 56.88  ? 343 ILE A CA  1 
ATOM   5767 C C   . ILE C 3 343 ? 168.441 142.549 158.062 1.00 66.65  ? 343 ILE A C   1 
ATOM   5768 O O   . ILE C 3 343 ? 167.546 143.371 157.823 1.00 70.33  ? 343 ILE A O   1 
ATOM   5769 C CB  . ILE C 3 343 ? 170.375 143.152 159.586 1.00 52.83  ? 343 ILE A CB  1 
ATOM   5770 C CG1 . ILE C 3 343 ? 170.664 143.497 161.044 1.00 54.96  ? 343 ILE A CG1 1 
ATOM   5771 C CG2 . ILE C 3 343 ? 170.379 144.414 158.744 1.00 61.76  ? 343 ILE A CG2 1 
ATOM   5772 C CD1 . ILE C 3 343 ? 172.045 144.065 161.266 1.00 56.59  ? 343 ILE A CD1 1 
ATOM   5773 N N   . ILE C 3 344 ? 168.934 141.745 157.117 1.00 63.74  ? 344 ILE A N   1 
ATOM   5774 C CA  . ILE C 3 344 ? 168.412 141.789 155.753 1.00 48.01  ? 344 ILE A CA  1 
ATOM   5775 C C   . ILE C 3 344 ? 166.939 141.404 155.736 1.00 48.77  ? 344 ILE A C   1 
ATOM   5776 O O   . ILE C 3 344 ? 166.123 142.038 155.054 1.00 62.09  ? 344 ILE A O   1 
ATOM   5777 C CB  . ILE C 3 344 ? 169.246 140.881 154.831 1.00 44.84  ? 344 ILE A CB  1 
ATOM   5778 C CG1 . ILE C 3 344 ? 170.475 141.622 154.317 1.00 55.22  ? 344 ILE A CG1 1 
ATOM   5779 C CG2 . ILE C 3 344 ? 168.421 140.398 153.659 1.00 56.89  ? 344 ILE A CG2 1 
ATOM   5780 C CD1 . ILE C 3 344 ? 171.346 140.785 153.417 1.00 59.94  ? 344 ILE A CD1 1 
ATOM   5781 N N   . LYS C 3 345 ? 166.575 140.359 156.484 1.00 59.88  ? 345 LYS A N   1 
ATOM   5782 C CA  . LYS C 3 345 ? 165.178 139.940 156.517 1.00 65.46  ? 345 LYS A CA  1 
ATOM   5783 C C   . LYS C 3 345 ? 164.286 141.031 157.095 1.00 70.67  ? 345 LYS A C   1 
ATOM   5784 O O   . LYS C 3 345 ? 163.199 141.301 156.567 1.00 75.86  ? 345 LYS A O   1 
ATOM   5785 C CB  . LYS C 3 345 ? 165.031 138.648 157.320 1.00 71.51  ? 345 LYS A CB  1 
ATOM   5786 C CG  . LYS C 3 345 ? 165.103 137.383 156.482 1.00 73.97  ? 345 LYS A CG  1 
ATOM   5787 C CD  . LYS C 3 345 ? 165.279 136.154 157.358 1.00 74.69  ? 345 LYS A CD  1 
ATOM   5788 C CE  . LYS C 3 345 ? 166.012 135.049 156.619 1.00 75.81  ? 345 LYS A CE  1 
ATOM   5789 N NZ  . LYS C 3 345 ? 165.323 134.672 155.355 1.00 78.79  ? 345 LYS A NZ  1 
ATOM   5790 N N   . ASN C 3 346 ? 164.730 141.674 158.178 1.00 76.80  ? 346 ASN A N   1 
ATOM   5791 C CA  . ASN C 3 346 ? 163.945 142.751 158.772 1.00 74.87  ? 346 ASN A CA  1 
ATOM   5792 C C   . ASN C 3 346 ? 163.793 143.921 157.809 1.00 78.76  ? 346 ASN A C   1 
ATOM   5793 O O   . ASN C 3 346 ? 162.708 144.506 157.699 1.00 86.19  ? 346 ASN A O   1 
ATOM   5794 C CB  . ASN C 3 346 ? 164.588 143.213 160.079 1.00 73.18  ? 346 ASN A CB  1 
ATOM   5795 C CG  . ASN C 3 346 ? 164.310 142.269 161.230 1.00 82.16  ? 346 ASN A CG  1 
ATOM   5796 O OD1 . ASN C 3 346 ? 163.630 141.257 161.066 1.00 86.34  ? 346 ASN A OD1 1 
ATOM   5797 N ND2 . ASN C 3 346 ? 164.836 142.597 162.404 1.00 81.04  ? 346 ASN A ND2 1 
ATOM   5798 N N   . ASN C 3 347 ? 164.870 144.281 157.106 1.00 73.50  ? 347 ASN A N   1 
ATOM   5799 C CA  . ASN C 3 347 ? 164.790 145.380 156.150 1.00 70.28  ? 347 ASN A CA  1 
ATOM   5800 C C   . ASN C 3 347 ? 163.825 145.059 155.016 1.00 75.44  ? 347 ASN A C   1 
ATOM   5801 O O   . ASN C 3 347 ? 163.053 145.923 154.586 1.00 73.54  ? 347 ASN A O   1 
ATOM   5802 C CB  . ASN C 3 347 ? 166.177 145.703 155.600 1.00 66.29  ? 347 ASN A CB  1 
ATOM   5803 C CG  . ASN C 3 347 ? 166.972 146.593 156.526 1.00 70.07  ? 347 ASN A CG  1 
ATOM   5804 O OD1 . ASN C 3 347 ? 166.419 147.209 157.435 1.00 74.28  ? 347 ASN A OD1 1 
ATOM   5805 N ND2 . ASN C 3 347 ? 168.277 146.666 156.302 1.00 72.93  ? 347 ASN A ND2 1 
ATOM   5806 N N   . LEU C 3 348 ? 163.860 143.823 154.510 1.00 79.58  ? 348 LEU A N   1 
ATOM   5807 C CA  . LEU C 3 348 ? 162.921 143.439 153.460 1.00 71.59  ? 348 LEU A CA  1 
ATOM   5808 C C   . LEU C 3 348 ? 161.485 143.473 153.963 1.00 74.64  ? 348 LEU A C   1 
ATOM   5809 O O   . LEU C 3 348 ? 160.580 143.915 153.245 1.00 79.44  ? 348 LEU A O   1 
ATOM   5810 C CB  . LEU C 3 348 ? 163.269 142.054 152.915 1.00 72.14  ? 348 LEU A CB  1 
ATOM   5811 C CG  . LEU C 3 348 ? 164.429 142.020 151.923 1.00 73.35  ? 348 LEU A CG  1 
ATOM   5812 C CD1 . LEU C 3 348 ? 164.497 140.687 151.204 1.00 73.87  ? 348 LEU A CD1 1 
ATOM   5813 C CD2 . LEU C 3 348 ? 164.239 143.141 150.929 1.00 76.73  ? 348 LEU A CD2 1 
ATOM   5814 N N   . LYS C 3 349 ? 161.255 143.014 155.194 1.00 88.16  ? 349 LYS A N   1 
ATOM   5815 C CA  . LYS C 3 349 ? 159.900 143.029 155.735 1.00 90.23  ? 349 LYS A CA  1 
ATOM   5816 C C   . LYS C 3 349 ? 159.404 144.452 155.966 1.00 92.06  ? 349 LYS A C   1 
ATOM   5817 O O   . LYS C 3 349 ? 158.205 144.719 155.822 1.00 91.76  ? 349 LYS A O   1 
ATOM   5818 C CB  . LYS C 3 349 ? 159.844 142.218 157.031 1.00 88.63  ? 349 LYS A CB  1 
ATOM   5819 C CG  . LYS C 3 349 ? 158.484 142.210 157.710 1.00 91.28  ? 349 LYS A CG  1 
ATOM   5820 C CD  . LYS C 3 349 ? 157.624 141.061 157.207 1.00 94.94  ? 349 LYS A CD  1 
ATOM   5821 C CE  . LYS C 3 349 ? 158.186 139.718 157.638 1.00 94.74  ? 349 LYS A CE  1 
ATOM   5822 N NZ  . LYS C 3 349 ? 157.381 138.586 157.104 1.00 92.98  ? 349 LYS A NZ  1 
ATOM   5823 N N   . ASP C 3 350 ? 160.304 145.376 156.317 1.00 94.81  ? 350 ASP A N   1 
ATOM   5824 C CA  . ASP C 3 350 ? 159.892 146.749 156.597 1.00 92.95  ? 350 ASP A CA  1 
ATOM   5825 C C   . ASP C 3 350 ? 159.348 147.443 155.353 1.00 96.99  ? 350 ASP A C   1 
ATOM   5826 O O   . ASP C 3 350 ? 158.344 148.162 155.428 1.00 98.23  ? 350 ASP A O   1 
ATOM   5827 C CB  . ASP C 3 350 ? 161.064 147.541 157.174 1.00 91.71  ? 350 ASP A CB  1 
ATOM   5828 C CG  . ASP C 3 350 ? 161.372 147.163 158.608 1.00 100.01 ? 350 ASP A CG  1 
ATOM   5829 O OD1 . ASP C 3 350 ? 160.424 146.856 159.360 1.00 101.95 ? 350 ASP A OD1 1 
ATOM   5830 O OD2 . ASP C 3 350 ? 162.563 147.173 158.984 1.00 104.01 ? 350 ASP A OD2 1 
ATOM   5831 N N   . CYS C 3 351 ? 159.989 147.243 154.204 1.00 101.00 ? 351 CYS A N   1 
ATOM   5832 C CA  . CYS C 3 351 ? 159.619 147.945 152.980 1.00 100.59 ? 351 CYS A CA  1 
ATOM   5833 C C   . CYS C 3 351 ? 158.421 147.325 152.269 1.00 99.72  ? 351 CYS A C   1 
ATOM   5834 O O   . CYS C 3 351 ? 158.160 147.677 151.113 1.00 100.16 ? 351 CYS A O   1 
ATOM   5835 C CB  . CYS C 3 351 ? 160.817 148.005 152.028 1.00 98.27  ? 351 CYS A CB  1 
ATOM   5836 S SG  . CYS C 3 351 ? 161.119 146.489 151.101 1.00 101.72 ? 351 CYS A SG  1 
ATOM   5837 N N   . GLY C 3 352 ? 157.691 146.428 152.923 1.00 97.39  ? 352 GLY A N   1 
ATOM   5838 C CA  . GLY C 3 352 ? 156.513 145.828 152.322 1.00 95.07  ? 352 GLY A CA  1 
ATOM   5839 C C   . GLY C 3 352 ? 156.789 144.998 151.088 1.00 98.99  ? 352 GLY A C   1 
ATOM   5840 O O   . GLY C 3 352 ? 156.069 145.122 150.090 1.00 104.15 ? 352 GLY A O   1 
ATOM   5841 N N   . LEU C 3 353 ? 157.817 144.155 151.129 1.00 94.04  ? 353 LEU A N   1 
ATOM   5842 C CA  . LEU C 3 353 ? 158.182 143.320 149.994 1.00 88.82  ? 353 LEU A CA  1 
ATOM   5843 C C   . LEU C 3 353 ? 158.291 141.845 150.354 1.00 95.66  ? 353 LEU A C   1 
ATOM   5844 O O   . LEU C 3 353 ? 158.004 140.995 149.508 1.00 96.64  ? 353 LEU A O   1 
ATOM   5845 C CB  . LEU C 3 353 ? 159.519 143.799 149.402 1.00 87.43  ? 353 LEU A CB  1 
ATOM   5846 C CG  . LEU C 3 353 ? 160.274 143.030 148.314 1.00 93.96  ? 353 LEU A CG  1 
ATOM   5847 C CD1 . LEU C 3 353 ? 159.338 142.529 147.224 1.00 95.02  ? 353 LEU A CD1 1 
ATOM   5848 C CD2 . LEU C 3 353 ? 161.384 143.885 147.721 1.00 93.83  ? 353 LEU A CD2 1 
ATOM   5849 N N   . PHE C 3 354 ? 158.674 141.521 151.586 1.00 114.92 ? 354 PHE A N   1 
ATOM   5850 C CA  . PHE C 3 354 ? 158.802 140.137 152.036 1.00 114.88 ? 354 PHE A CA  1 
ATOM   5851 C C   . PHE C 3 354 ? 157.478 139.386 151.935 1.00 115.51 ? 354 PHE A C   1 
ATOM   5852 O O   . PHE C 3 354 ? 157.230 138.444 152.687 1.00 114.96 ? 354 PHE A O   1 
ATOM   5853 C CB  . PHE C 3 354 ? 159.315 140.094 153.477 1.00 110.34 ? 354 PHE A CB  1 
ATOM   5854 C CG  . PHE C 3 354 ? 160.254 138.957 153.756 1.00 108.42 ? 354 PHE A CG  1 
ATOM   5855 C CD1 . PHE C 3 354 ? 161.485 138.887 153.127 1.00 111.20 ? 354 PHE A CD1 1 
ATOM   5856 C CD2 . PHE C 3 354 ? 159.912 137.964 154.659 1.00 107.02 ? 354 PHE A CD2 1 
ATOM   5857 C CE1 . PHE C 3 354 ? 162.353 137.845 153.386 1.00 112.87 ? 354 PHE A CE1 1 
ATOM   5858 C CE2 . PHE C 3 354 ? 160.777 136.920 154.922 1.00 108.80 ? 354 PHE A CE2 1 
ATOM   5859 C CZ  . PHE C 3 354 ? 161.998 136.860 154.285 1.00 110.67 ? 354 PHE A CZ  1 
ATOM   5860 N N   . GLU D 4 21  ? 156.123 115.565 215.722 1.00 149.08 ? 3   GLU B N   1 
ATOM   5861 C CA  . GLU D 4 21  ? 156.556 115.088 214.414 1.00 151.08 ? 3   GLU B CA  1 
ATOM   5862 C C   . GLU D 4 21  ? 156.153 116.081 213.326 1.00 152.64 ? 3   GLU B C   1 
ATOM   5863 O O   . GLU D 4 21  ? 155.312 116.952 213.554 1.00 151.83 ? 3   GLU B O   1 
ATOM   5864 C CB  . GLU D 4 21  ? 155.965 113.704 214.126 1.00 150.50 ? 3   GLU B CB  1 
ATOM   5865 C CG  . GLU D 4 21  ? 156.722 112.900 213.080 1.00 150.29 ? 3   GLU B CG  1 
ATOM   5866 C CD  . GLU D 4 21  ? 156.222 111.474 212.965 1.00 149.83 ? 3   GLU B CD  1 
ATOM   5867 O OE1 . GLU D 4 21  ? 155.344 111.085 213.762 1.00 149.70 ? 3   GLU B OE1 1 
ATOM   5868 O OE2 . GLU D 4 21  ? 156.707 110.744 212.075 1.00 150.18 ? 3   GLU B OE2 1 
ATOM   5869 N N   . LEU D 4 22  ? 156.765 115.947 212.147 1.00 150.30 ? 4   LEU B N   1 
ATOM   5870 C CA  . LEU D 4 22  ? 156.455 116.849 211.041 1.00 148.74 ? 4   LEU B CA  1 
ATOM   5871 C C   . LEU D 4 22  ? 154.995 116.733 210.625 1.00 147.74 ? 4   LEU B C   1 
ATOM   5872 O O   . LEU D 4 22  ? 154.341 117.742 210.336 1.00 147.51 ? 4   LEU B O   1 
ATOM   5873 C CB  . LEU D 4 22  ? 157.376 116.560 209.857 1.00 146.45 ? 4   LEU B CB  1 
ATOM   5874 C CG  . LEU D 4 22  ? 158.877 116.629 210.145 1.00 146.53 ? 4   LEU B CG  1 
ATOM   5875 C CD1 . LEU D 4 22  ? 159.680 116.206 208.925 1.00 146.10 ? 4   LEU B CD1 1 
ATOM   5876 C CD2 . LEU D 4 22  ? 159.270 118.028 210.593 1.00 146.97 ? 4   LEU B CD2 1 
ATOM   5877 N N   . ASP D 4 23  ? 154.468 115.507 210.582 1.00 153.68 ? 5   ASP B N   1 
ATOM   5878 C CA  . ASP D 4 23  ? 153.064 115.318 210.237 1.00 155.47 ? 5   ASP B CA  1 
ATOM   5879 C C   . ASP D 4 23  ? 152.153 115.970 211.269 1.00 155.57 ? 5   ASP B C   1 
ATOM   5880 O O   . ASP D 4 23  ? 151.132 116.573 210.916 1.00 155.01 ? 5   ASP B O   1 
ATOM   5881 C CB  . ASP D 4 23  ? 152.752 113.828 210.106 1.00 155.87 ? 5   ASP B CB  1 
ATOM   5882 C CG  . ASP D 4 23  ? 153.475 113.183 208.940 1.00 155.62 ? 5   ASP B CG  1 
ATOM   5883 O OD1 . ASP D 4 23  ? 153.822 113.906 207.982 1.00 156.17 ? 5   ASP B OD1 1 
ATOM   5884 O OD2 . ASP D 4 23  ? 153.696 111.955 208.981 1.00 153.73 ? 5   ASP B OD2 1 
ATOM   5885 N N   . GLN D 4 24  ? 152.504 115.857 212.552 1.00 154.43 ? 6   GLN B N   1 
ATOM   5886 C CA  . GLN D 4 24  ? 151.714 116.503 213.596 1.00 155.78 ? 6   GLN B CA  1 
ATOM   5887 C C   . GLN D 4 24  ? 151.726 118.018 213.436 1.00 154.53 ? 6   GLN B C   1 
ATOM   5888 O O   . GLN D 4 24  ? 150.688 118.676 213.581 1.00 152.29 ? 6   GLN B O   1 
ATOM   5889 C CB  . GLN D 4 24  ? 152.241 116.101 214.973 1.00 154.01 ? 6   GLN B CB  1 
ATOM   5890 C CG  . GLN D 4 24  ? 151.537 116.780 216.136 1.00 154.54 ? 6   GLN B CG  1 
ATOM   5891 C CD  . GLN D 4 24  ? 150.031 116.622 216.078 1.00 155.50 ? 6   GLN B CD  1 
ATOM   5892 O OE1 . GLN D 4 24  ? 149.296 117.601 215.946 1.00 155.26 ? 6   GLN B OE1 1 
ATOM   5893 N NE2 . GLN D 4 24  ? 149.562 115.383 216.179 1.00 154.49 ? 6   GLN B NE2 1 
ATOM   5894 N N   . LEU D 4 25  ? 152.894 118.590 213.133 1.00 147.51 ? 7   LEU B N   1 
ATOM   5895 C CA  . LEU D 4 25  ? 152.981 120.032 212.928 1.00 147.59 ? 7   LEU B CA  1 
ATOM   5896 C C   . LEU D 4 25  ? 152.160 120.469 211.722 1.00 146.26 ? 7   LEU B C   1 
ATOM   5897 O O   . LEU D 4 25  ? 151.483 121.503 211.765 1.00 146.63 ? 7   LEU B O   1 
ATOM   5898 C CB  . LEU D 4 25  ? 154.442 120.451 212.769 1.00 146.39 ? 7   LEU B CB  1 
ATOM   5899 N N   . ARG D 4 26  ? 152.206 119.695 210.635 1.00 145.99 ? 8   ARG B N   1 
ATOM   5900 C CA  . ARG D 4 26  ? 151.415 120.033 209.456 1.00 147.06 ? 8   ARG B CA  1 
ATOM   5901 C C   . ARG D 4 26  ? 149.922 119.958 209.752 1.00 147.20 ? 8   ARG B C   1 
ATOM   5902 O O   . ARG D 4 26  ? 149.146 120.815 209.307 1.00 147.57 ? 8   ARG B O   1 
ATOM   5903 C CB  . ARG D 4 26  ? 151.783 119.109 208.296 1.00 146.11 ? 8   ARG B CB  1 
ATOM   5904 C CG  . ARG D 4 26  ? 153.093 119.465 207.614 1.00 146.45 ? 8   ARG B CG  1 
ATOM   5905 N N   . GLN D 4 27  ? 149.498 118.935 210.498 1.00 145.97 ? 9   GLN B N   1 
ATOM   5906 C CA  . GLN D 4 27  ? 148.091 118.822 210.864 1.00 147.41 ? 9   GLN B CA  1 
ATOM   5907 C C   . GLN D 4 27  ? 147.658 119.990 211.740 1.00 146.01 ? 9   GLN B C   1 
ATOM   5908 O O   . GLN D 4 27  ? 146.560 120.534 211.568 1.00 144.73 ? 9   GLN B O   1 
ATOM   5909 C CB  . GLN D 4 27  ? 147.841 117.493 211.576 1.00 148.10 ? 9   GLN B CB  1 
ATOM   5910 C CG  . GLN D 4 27  ? 147.754 116.295 210.643 1.00 147.58 ? 9   GLN B CG  1 
ATOM   5911 N N   . GLU D 4 28  ? 148.511 120.391 212.686 1.00 136.19 ? 10  GLU B N   1 
ATOM   5912 C CA  . GLU D 4 28  ? 148.187 121.538 213.527 1.00 136.87 ? 10  GLU B CA  1 
ATOM   5913 C C   . GLU D 4 28  ? 148.104 122.817 212.706 1.00 137.42 ? 10  GLU B C   1 
ATOM   5914 O O   . GLU D 4 28  ? 147.247 123.671 212.959 1.00 136.08 ? 10  GLU B O   1 
ATOM   5915 C CB  . GLU D 4 28  ? 149.217 121.683 214.647 1.00 135.20 ? 10  GLU B CB  1 
ATOM   5916 C CG  . GLU D 4 28  ? 148.676 121.360 216.033 1.00 136.65 ? 10  GLU B CG  1 
ATOM   5917 C CD  . GLU D 4 28  ? 147.658 122.374 216.529 1.00 137.21 ? 10  GLU B CD  1 
ATOM   5918 O OE1 . GLU D 4 28  ? 147.476 123.422 215.873 1.00 136.65 ? 10  GLU B OE1 1 
ATOM   5919 O OE2 . GLU D 4 28  ? 147.036 122.120 217.581 1.00 137.86 ? 10  GLU B OE2 1 
ATOM   5920 N N   . ALA D 4 29  ? 148.992 122.972 211.721 1.00 135.88 ? 11  ALA B N   1 
ATOM   5921 C CA  . ALA D 4 29  ? 148.932 124.140 210.848 1.00 133.92 ? 11  ALA B CA  1 
ATOM   5922 C C   . ALA D 4 29  ? 147.638 124.161 210.044 1.00 133.73 ? 11  ALA B C   1 
ATOM   5923 O O   . ALA D 4 29  ? 147.020 125.219 209.873 1.00 135.05 ? 11  ALA B O   1 
ATOM   5924 C CB  . ALA D 4 29  ? 150.144 124.163 209.918 1.00 132.98 ? 11  ALA B CB  1 
ATOM   5925 N N   . GLU D 4 30  ? 147.216 123.001 209.535 1.00 130.12 ? 12  GLU B N   1 
ATOM   5926 C CA  . GLU D 4 30  ? 145.953 122.935 208.804 1.00 131.48 ? 12  GLU B CA  1 
ATOM   5927 C C   . GLU D 4 30  ? 144.777 123.283 209.710 1.00 132.03 ? 12  GLU B C   1 
ATOM   5928 O O   . GLU D 4 30  ? 143.858 124.008 209.304 1.00 131.02 ? 12  GLU B O   1 
ATOM   5929 C CB  . GLU D 4 30  ? 145.773 121.546 208.195 1.00 130.02 ? 12  GLU B CB  1 
ATOM   5930 C CG  . GLU D 4 30  ? 144.441 121.340 207.494 1.00 131.17 ? 12  GLU B CG  1 
ATOM   5931 C CD  . GLU D 4 30  ? 144.502 121.672 206.015 1.00 132.09 ? 12  GLU B CD  1 
ATOM   5932 O OE1 . GLU D 4 30  ? 145.441 122.383 205.601 1.00 131.77 ? 12  GLU B OE1 1 
ATOM   5933 O OE2 . GLU D 4 30  ? 143.610 121.219 205.267 1.00 132.86 ? 12  GLU B OE2 1 
ATOM   5934 N N   . GLN D 4 31  ? 144.794 122.779 210.946 1.00 122.86 ? 13  GLN B N   1 
ATOM   5935 C CA  . GLN D 4 31  ? 143.733 123.110 211.891 1.00 122.26 ? 13  GLN B CA  1 
ATOM   5936 C C   . GLN D 4 31  ? 143.719 124.602 212.200 1.00 122.27 ? 13  GLN B C   1 
ATOM   5937 O O   . GLN D 4 31  ? 142.650 125.210 212.315 1.00 119.72 ? 13  GLN B O   1 
ATOM   5938 C CB  . GLN D 4 31  ? 143.898 122.296 213.173 1.00 122.09 ? 13  GLN B CB  1 
ATOM   5939 C CG  . GLN D 4 31  ? 142.862 122.605 214.240 1.00 123.52 ? 13  GLN B CG  1 
ATOM   5940 C CD  . GLN D 4 31  ? 142.304 121.354 214.887 1.00 124.02 ? 13  GLN B CD  1 
ATOM   5941 O OE1 . GLN D 4 31  ? 142.562 120.239 214.433 1.00 124.38 ? 13  GLN B OE1 1 
ATOM   5942 N NE2 . GLN D 4 31  ? 141.535 121.532 215.955 1.00 123.36 ? 13  GLN B NE2 1 
ATOM   5943 N N   . LEU D 4 32  ? 144.899 125.211 212.336 1.00 115.56 ? 14  LEU B N   1 
ATOM   5944 C CA  . LEU D 4 32  ? 144.972 126.646 212.589 1.00 114.69 ? 14  LEU B CA  1 
ATOM   5945 C C   . LEU D 4 32  ? 144.447 127.448 211.403 1.00 116.72 ? 14  LEU B C   1 
ATOM   5946 O O   . LEU D 4 32  ? 143.785 128.478 211.584 1.00 118.32 ? 14  LEU B O   1 
ATOM   5947 C CB  . LEU D 4 32  ? 146.409 127.045 212.917 1.00 111.24 ? 14  LEU B CB  1 
ATOM   5948 C CG  . LEU D 4 32  ? 146.833 126.797 214.364 1.00 113.09 ? 14  LEU B CG  1 
ATOM   5949 C CD1 . LEU D 4 32  ? 148.346 126.722 214.473 1.00 114.81 ? 14  LEU B CD1 1 
ATOM   5950 C CD2 . LEU D 4 32  ? 146.281 127.876 215.278 1.00 114.21 ? 14  LEU B CD2 1 
ATOM   5951 N N   . LYS D 4 33  ? 144.744 127.000 210.182 1.00 116.67 ? 15  LYS B N   1 
ATOM   5952 C CA  . LYS D 4 33  ? 144.201 127.667 209.003 1.00 114.86 ? 15  LYS B CA  1 
ATOM   5953 C C   . LYS D 4 33  ? 142.680 127.574 208.975 1.00 116.22 ? 15  LYS B C   1 
ATOM   5954 O O   . LYS D 4 33  ? 141.993 128.552 208.651 1.00 119.48 ? 15  LYS B O   1 
ATOM   5955 C CB  . LYS D 4 33  ? 144.803 127.064 207.735 1.00 114.49 ? 15  LYS B CB  1 
ATOM   5956 C CG  . LYS D 4 33  ? 144.606 127.908 206.489 1.00 117.70 ? 15  LYS B CG  1 
ATOM   5957 N N   . ASN D 4 34  ? 142.135 126.405 209.319 1.00 112.00 ? 16  ASN B N   1 
ATOM   5958 C CA  . ASN D 4 34  ? 140.683 126.271 209.406 1.00 114.57 ? 16  ASN B CA  1 
ATOM   5959 C C   . ASN D 4 34  ? 140.114 127.170 210.498 1.00 114.02 ? 16  ASN B C   1 
ATOM   5960 O O   . ASN D 4 34  ? 139.013 127.718 210.356 1.00 113.05 ? 16  ASN B O   1 
ATOM   5961 C CB  . ASN D 4 34  ? 140.302 124.813 209.654 1.00 115.94 ? 16  ASN B CB  1 
ATOM   5962 C CG  . ASN D 4 34  ? 139.692 124.156 208.433 1.00 116.73 ? 16  ASN B CG  1 
ATOM   5963 O OD1 . ASN D 4 34  ? 138.836 124.737 207.765 1.00 114.62 ? 16  ASN B OD1 1 
ATOM   5964 N ND2 . ASN D 4 34  ? 140.128 122.938 208.135 1.00 117.08 ? 16  ASN B ND2 1 
ATOM   5965 N N   . GLN D 4 35  ? 140.849 127.323 211.601 1.00 108.60 ? 17  GLN B N   1 
ATOM   5966 C CA  . GLN D 4 35  ? 140.429 128.226 212.667 1.00 110.69 ? 17  GLN B CA  1 
ATOM   5967 C C   . GLN D 4 35  ? 140.351 129.662 212.165 1.00 112.29 ? 17  GLN B C   1 
ATOM   5968 O O   . GLN D 4 35  ? 139.383 130.382 212.441 1.00 113.67 ? 17  GLN B O   1 
ATOM   5969 C CB  . GLN D 4 35  ? 141.397 128.112 213.846 1.00 107.92 ? 17  GLN B CB  1 
ATOM   5970 C CG  . GLN D 4 35  ? 141.413 129.316 214.766 1.00 109.76 ? 17  GLN B CG  1 
ATOM   5971 C CD  . GLN D 4 35  ? 141.435 128.926 216.228 1.00 111.20 ? 17  GLN B CD  1 
ATOM   5972 O OE1 . GLN D 4 35  ? 142.117 127.978 216.618 1.00 111.43 ? 17  GLN B OE1 1 
ATOM   5973 N NE2 . GLN D 4 35  ? 140.686 129.653 217.048 1.00 110.99 ? 17  GLN B NE2 1 
ATOM   5974 N N   . ILE D 4 36  ? 141.367 130.090 211.414 1.00 107.72 ? 18  ILE B N   1 
ATOM   5975 C CA  . ILE D 4 36  ? 141.358 131.428 210.827 1.00 106.63 ? 18  ILE B CA  1 
ATOM   5976 C C   . ILE D 4 36  ? 140.167 131.586 209.892 1.00 107.86 ? 18  ILE B C   1 
ATOM   5977 O O   . ILE D 4 36  ? 139.483 132.619 209.896 1.00 110.24 ? 18  ILE B O   1 
ATOM   5978 C CB  . ILE D 4 36  ? 142.687 131.698 210.097 1.00 106.54 ? 18  ILE B CB  1 
ATOM   5979 C CG1 . ILE D 4 36  ? 143.818 131.925 211.099 1.00 105.02 ? 18  ILE B CG1 1 
ATOM   5980 C CG2 . ILE D 4 36  ? 142.557 132.895 209.167 1.00 107.65 ? 18  ILE B CG2 1 
ATOM   5981 C CD1 . ILE D 4 36  ? 143.725 133.244 211.820 1.00 109.19 ? 18  ILE B CD1 1 
ATOM   5982 N N   . ARG D 4 37  ? 139.901 130.562 209.078 1.00 110.57 ? 19  ARG B N   1 
ATOM   5983 C CA  . ARG D 4 37  ? 138.788 130.628 208.136 1.00 110.38 ? 19  ARG B CA  1 
ATOM   5984 C C   . ARG D 4 37  ? 137.457 130.788 208.861 1.00 107.77 ? 19  ARG B C   1 
ATOM   5985 O O   . ARG D 4 37  ? 136.630 131.632 208.490 1.00 108.92 ? 19  ARG B O   1 
ATOM   5986 C CB  . ARG D 4 37  ? 138.774 129.377 207.258 1.00 112.70 ? 19  ARG B CB  1 
ATOM   5987 C CG  . ARG D 4 37  ? 138.105 129.572 205.910 1.00 112.74 ? 19  ARG B CG  1 
ATOM   5988 C CD  . ARG D 4 37  ? 138.598 128.551 204.900 1.00 113.61 ? 19  ARG B CD  1 
ATOM   5989 N NE  . ARG D 4 37  ? 138.598 127.203 205.455 1.00 117.26 ? 19  ARG B NE  1 
ATOM   5990 C CZ  . ARG D 4 37  ? 138.437 126.099 204.739 1.00 117.05 ? 19  ARG B CZ  1 
ATOM   5991 N NH1 . ARG D 4 37  ? 138.245 126.145 203.431 1.00 114.77 ? 19  ARG B NH1 1 
ATOM   5992 N NH2 . ARG D 4 37  ? 138.466 124.919 205.351 1.00 115.00 ? 19  ARG B NH2 1 
ATOM   5993 N N   . ASP D 4 38  ? 137.231 129.987 209.906 1.00 103.26 ? 20  ASP B N   1 
ATOM   5994 C CA  . ASP D 4 38  ? 135.948 130.070 210.596 1.00 107.20 ? 20  ASP B CA  1 
ATOM   5995 C C   . ASP D 4 38  ? 135.821 131.368 211.381 1.00 106.37 ? 20  ASP B C   1 
ATOM   5996 O O   . ASP D 4 38  ? 134.718 131.911 211.493 1.00 105.12 ? 20  ASP B O   1 
ATOM   5997 C CB  . ASP D 4 38  ? 135.726 128.851 211.501 1.00 109.48 ? 20  ASP B CB  1 
ATOM   5998 C CG  . ASP D 4 38  ? 136.757 128.726 212.607 1.00 110.82 ? 20  ASP B CG  1 
ATOM   5999 O OD1 . ASP D 4 38  ? 136.919 129.672 213.407 1.00 110.27 ? 20  ASP B OD1 1 
ATOM   6000 O OD2 . ASP D 4 38  ? 137.387 127.653 212.694 1.00 110.19 ? 20  ASP B OD2 1 
ATOM   6001 N N   . ALA D 4 39  ? 136.928 131.890 211.918 1.00 100.35 ? 21  ALA B N   1 
ATOM   6002 C CA  . ALA D 4 39  ? 136.874 133.194 212.571 1.00 98.92  ? 21  ALA B CA  1 
ATOM   6003 C C   . ALA D 4 39  ? 136.500 134.289 211.580 1.00 102.69 ? 21  ALA B C   1 
ATOM   6004 O O   . ALA D 4 39  ? 135.668 135.157 211.882 1.00 105.70 ? 21  ALA B O   1 
ATOM   6005 C CB  . ALA D 4 39  ? 138.214 133.508 213.235 1.00 99.16  ? 21  ALA B CB  1 
ATOM   6006 N N   . ARG D 4 40  ? 137.102 134.263 210.387 1.00 100.95 ? 22  ARG B N   1 
ATOM   6007 C CA  . ARG D 4 40  ? 136.765 135.253 209.369 1.00 98.25  ? 22  ARG B CA  1 
ATOM   6008 C C   . ARG D 4 40  ? 135.302 135.151 208.967 1.00 97.94  ? 22  ARG B C   1 
ATOM   6009 O O   . ARG D 4 40  ? 134.628 136.171 208.786 1.00 93.87  ? 22  ARG B O   1 
ATOM   6010 C CB  . ARG D 4 40  ? 137.660 135.081 208.145 1.00 97.69  ? 22  ARG B CB  1 
ATOM   6011 C CG  . ARG D 4 40  ? 138.976 135.820 208.222 1.00 95.75  ? 22  ARG B CG  1 
ATOM   6012 C CD  . ARG D 4 40  ? 140.044 135.057 207.471 1.00 97.97  ? 22  ARG B CD  1 
ATOM   6013 N NE  . ARG D 4 40  ? 141.235 135.862 207.235 1.00 100.62 ? 22  ARG B NE  1 
ATOM   6014 C CZ  . ARG D 4 40  ? 142.225 135.508 206.428 1.00 99.75  ? 22  ARG B CZ  1 
ATOM   6015 N NH1 . ARG D 4 40  ? 142.195 134.370 205.754 1.00 100.03 ? 22  ARG B NH1 1 
ATOM   6016 N NH2 . ARG D 4 40  ? 143.269 136.320 206.287 1.00 98.02  ? 22  ARG B NH2 1 
ATOM   6017 N N   . LYS D 4 41  ? 134.799 133.925 208.806 1.00 102.14 ? 23  LYS B N   1 
ATOM   6018 C CA  . LYS D 4 41  ? 133.387 133.736 208.481 1.00 99.96  ? 23  LYS B CA  1 
ATOM   6019 C C   . LYS D 4 41  ? 132.500 134.282 209.596 1.00 96.14  ? 23  LYS B C   1 
ATOM   6020 O O   . LYS D 4 41  ? 131.502 134.962 209.330 1.00 94.24  ? 23  LYS B O   1 
ATOM   6021 C CB  . LYS D 4 41  ? 133.117 132.245 208.224 1.00 99.60  ? 23  LYS B CB  1 
ATOM   6022 C CG  . LYS D 4 41  ? 131.704 131.744 207.785 1.00 100.79 ? 23  LYS B CG  1 
ATOM   6023 N N   . ALA D 4 42  ? 132.866 134.020 210.852 1.00 99.42  ? 24  ALA B N   1 
ATOM   6024 C CA  . ALA D 4 42  ? 132.056 134.486 211.972 1.00 101.57 ? 24  ALA B CA  1 
ATOM   6025 C C   . ALA D 4 42  ? 132.033 136.007 212.048 1.00 101.52 ? 24  ALA B C   1 
ATOM   6026 O O   . ALA D 4 42  ? 131.011 136.599 212.414 1.00 103.30 ? 24  ALA B O   1 
ATOM   6027 C CB  . ALA D 4 42  ? 132.574 133.889 213.279 1.00 99.74  ? 24  ALA B CB  1 
ATOM   6028 N N   . CYS D 4 43  ? 133.145 136.659 211.708 1.00 107.75 ? 25  CYS B N   1 
ATOM   6029 C CA  . CYS D 4 43  ? 133.196 138.113 211.815 1.00 109.59 ? 25  CYS B CA  1 
ATOM   6030 C C   . CYS D 4 43  ? 132.346 138.825 210.768 1.00 109.27 ? 25  CYS B C   1 
ATOM   6031 O O   . CYS D 4 43  ? 132.141 140.037 210.890 1.00 107.52 ? 25  CYS B O   1 
ATOM   6032 C CB  . CYS D 4 43  ? 134.642 138.602 211.709 1.00 112.35 ? 25  CYS B CB  1 
ATOM   6033 S SG  . CYS D 4 43  ? 135.439 138.262 210.121 1.00 123.63 ? 25  CYS B SG  1 
ATOM   6034 N N   . ALA D 4 44  ? 131.849 138.117 209.756 1.00 105.44 ? 26  ALA B N   1 
ATOM   6035 C CA  . ALA D 4 44  ? 131.144 138.742 208.643 1.00 104.84 ? 26  ALA B CA  1 
ATOM   6036 C C   . ALA D 4 44  ? 129.639 138.716 208.874 1.00 102.87 ? 26  ALA B C   1 
ATOM   6037 O O   . ALA D 4 44  ? 129.095 137.720 209.363 1.00 104.18 ? 26  ALA B O   1 
ATOM   6038 C CB  . ALA D 4 44  ? 131.482 138.040 207.328 1.00 103.96 ? 26  ALA B CB  1 
ATOM   6039 N N   . ASP D 4 45  ? 128.972 139.816 208.522 1.00 94.47  ? 27  ASP B N   1 
ATOM   6040 C CA  . ASP D 4 45  ? 127.519 139.921 208.613 1.00 91.89  ? 27  ASP B CA  1 
ATOM   6041 C C   . ASP D 4 45  ? 126.875 140.103 207.242 1.00 92.31  ? 27  ASP B C   1 
ATOM   6042 O O   . ASP D 4 45  ? 126.001 139.323 206.853 1.00 95.77  ? 27  ASP B O   1 
ATOM   6043 C CB  . ASP D 4 45  ? 127.139 141.083 209.539 1.00 96.01  ? 27  ASP B CB  1 
ATOM   6044 C CG  . ASP D 4 45  ? 125.641 141.250 209.682 1.00 98.19  ? 27  ASP B CG  1 
ATOM   6045 O OD1 . ASP D 4 45  ? 124.905 140.258 209.497 1.00 100.37 ? 27  ASP B OD1 1 
ATOM   6046 O OD2 . ASP D 4 45  ? 125.197 142.379 209.978 1.00 97.53  ? 27  ASP B OD2 1 
ATOM   6047 N N   . ALA D 4 46  ? 127.297 141.123 206.499 1.00 96.75  ? 28  ALA B N   1 
ATOM   6048 C CA  . ALA D 4 46  ? 126.726 141.431 205.194 1.00 99.37  ? 28  ALA B CA  1 
ATOM   6049 C C   . ALA D 4 46  ? 127.864 141.783 204.243 1.00 100.37 ? 28  ALA B C   1 
ATOM   6050 O O   . ALA D 4 46  ? 129.043 141.587 204.554 1.00 103.50 ? 28  ALA B O   1 
ATOM   6051 C CB  . ALA D 4 46  ? 125.691 142.557 205.307 1.00 94.20  ? 28  ALA B CB  1 
ATOM   6052 N N   . THR D 4 47  ? 127.509 142.304 203.072 1.00 89.63  ? 29  THR B N   1 
ATOM   6053 C CA  . THR D 4 47  ? 128.474 142.669 202.047 1.00 89.79  ? 29  THR B CA  1 
ATOM   6054 C C   . THR D 4 47  ? 128.457 144.174 201.819 1.00 87.93  ? 29  THR B C   1 
ATOM   6055 O O   . THR D 4 47  ? 127.418 144.827 201.951 1.00 90.85  ? 29  THR B O   1 
ATOM   6056 C CB  . THR D 4 47  ? 128.184 141.950 200.727 1.00 91.09  ? 29  THR B CB  1 
ATOM   6057 O OG1 . THR D 4 47  ? 127.274 142.735 199.947 1.00 92.00  ? 29  THR B OG1 1 
ATOM   6058 C CG2 . THR D 4 47  ? 127.571 140.582 200.987 1.00 90.37  ? 29  THR B CG2 1 
ATOM   6059 N N   . LEU D 4 48  ? 129.626 144.721 201.474 1.00 84.72  ? 30  LEU B N   1 
ATOM   6060 C CA  . LEU D 4 48  ? 129.725 146.155 201.223 1.00 86.25  ? 30  LEU B CA  1 
ATOM   6061 C C   . LEU D 4 48  ? 128.875 146.573 200.030 1.00 88.31  ? 30  LEU B C   1 
ATOM   6062 O O   . LEU D 4 48  ? 128.330 147.683 200.017 1.00 94.20  ? 30  LEU B O   1 
ATOM   6063 C CB  . LEU D 4 48  ? 131.189 146.550 201.019 1.00 85.26  ? 30  LEU B CB  1 
ATOM   6064 C CG  . LEU D 4 48  ? 131.529 147.970 200.559 1.00 88.10  ? 30  LEU B CG  1 
ATOM   6065 C CD1 . LEU D 4 48  ? 130.898 149.020 201.447 1.00 91.28  ? 30  LEU B CD1 1 
ATOM   6066 C CD2 . LEU D 4 48  ? 133.037 148.157 200.526 1.00 87.63  ? 30  LEU B CD2 1 
ATOM   6067 N N   . SER D 4 49  ? 128.741 145.703 199.027 1.00 88.80  ? 31  SER B N   1 
ATOM   6068 C CA  . SER D 4 49  ? 127.856 146.008 197.909 1.00 91.03  ? 31  SER B CA  1 
ATOM   6069 C C   . SER D 4 49  ? 126.397 146.045 198.346 1.00 89.37  ? 31  SER B C   1 
ATOM   6070 O O   . SER D 4 49  ? 125.584 146.742 197.730 1.00 86.69  ? 31  SER B O   1 
ATOM   6071 C CB  . SER D 4 49  ? 128.050 144.988 196.789 1.00 89.59  ? 31  SER B CB  1 
ATOM   6072 O OG  . SER D 4 49  ? 127.498 145.459 195.572 1.00 91.60  ? 31  SER B OG  1 
ATOM   6073 N N   . GLN D 4 50  ? 126.049 145.305 199.400 1.00 87.43  ? 32  GLN B N   1 
ATOM   6074 C CA  . GLN D 4 50  ? 124.679 145.325 199.900 1.00 87.87  ? 32  GLN B CA  1 
ATOM   6075 C C   . GLN D 4 50  ? 124.368 146.635 200.612 1.00 84.47  ? 32  GLN B C   1 
ATOM   6076 O O   . GLN D 4 50  ? 123.298 147.220 200.407 1.00 87.41  ? 32  GLN B O   1 
ATOM   6077 C CB  . GLN D 4 50  ? 124.450 144.139 200.836 1.00 91.35  ? 32  GLN B CB  1 
ATOM   6078 C CG  . GLN D 4 50  ? 122.993 143.776 201.052 1.00 90.12  ? 32  GLN B CG  1 
ATOM   6079 C CD  . GLN D 4 50  ? 122.828 142.416 201.699 1.00 89.13  ? 32  GLN B CD  1 
ATOM   6080 O OE1 . GLN D 4 50  ? 123.328 142.175 202.797 1.00 88.61  ? 32  GLN B OE1 1 
ATOM   6081 N NE2 . GLN D 4 50  ? 122.125 141.518 201.019 1.00 89.36  ? 32  GLN B NE2 1 
ATOM   6082 N N   . ILE D 4 51  ? 125.287 147.105 201.457 1.00 85.99  ? 33  ILE B N   1 
ATOM   6083 C CA  . ILE D 4 51  ? 125.036 148.314 202.236 1.00 87.71  ? 33  ILE B CA  1 
ATOM   6084 C C   . ILE D 4 51  ? 124.919 149.530 201.326 1.00 93.75  ? 33  ILE B C   1 
ATOM   6085 O O   . ILE D 4 51  ? 124.012 150.356 201.486 1.00 97.52  ? 33  ILE B O   1 
ATOM   6086 C CB  . ILE D 4 51  ? 126.134 148.496 203.299 1.00 91.47  ? 33  ILE B CB  1 
ATOM   6087 C CG1 . ILE D 4 51  ? 125.770 147.724 204.567 1.00 95.31  ? 33  ILE B CG1 1 
ATOM   6088 C CG2 . ILE D 4 51  ? 126.345 149.966 203.618 1.00 92.54  ? 33  ILE B CG2 1 
ATOM   6089 C CD1 . ILE D 4 51  ? 126.812 147.805 205.654 1.00 94.24  ? 33  ILE B CD1 1 
ATOM   6090 N N   . THR D 4 52  ? 125.817 149.656 200.350 1.00 99.10  ? 34  THR B N   1 
ATOM   6091 C CA  . THR D 4 52  ? 125.800 150.812 199.461 1.00 100.77 ? 34  THR B CA  1 
ATOM   6092 C C   . THR D 4 52  ? 124.788 150.626 198.338 1.00 101.36 ? 34  THR B C   1 
ATOM   6093 O O   . THR D 4 52  ? 125.127 150.766 197.159 1.00 102.19 ? 34  THR B O   1 
ATOM   6094 C CB  . THR D 4 52  ? 127.193 151.062 198.879 1.00 98.24  ? 34  THR B CB  1 
ATOM   6095 O OG1 . THR D 4 52  ? 127.557 149.976 198.019 1.00 97.86  ? 34  THR B OG1 1 
ATOM   6096 C CG2 . THR D 4 52  ? 128.218 151.181 199.993 1.00 96.62  ? 34  THR B CG2 1 
ATOM   6097 N N   . ASN D 4 53  ? 123.544 150.312 198.694 1.00 102.59 ? 35  ASN B N   1 
ATOM   6098 C CA  . ASN D 4 53  ? 122.469 150.144 197.728 1.00 101.68 ? 35  ASN B CA  1 
ATOM   6099 C C   . ASN D 4 53  ? 121.538 151.345 197.662 1.00 98.88  ? 35  ASN B C   1 
ATOM   6100 O O   . ASN D 4 53  ? 120.560 151.314 196.909 1.00 99.90  ? 35  ASN B O   1 
ATOM   6101 C CB  . ASN D 4 53  ? 121.659 148.885 198.052 1.00 103.13 ? 35  ASN B CB  1 
ATOM   6102 C CG  . ASN D 4 53  ? 121.185 148.160 196.809 1.00 106.08 ? 35  ASN B CG  1 
ATOM   6103 O OD1 . ASN D 4 53  ? 121.115 148.741 195.726 1.00 106.00 ? 35  ASN B OD1 1 
ATOM   6104 N ND2 . ASN D 4 53  ? 120.857 146.882 196.958 1.00 104.20 ? 35  ASN B ND2 1 
ATOM   6105 N N   . ASN D 4 54  ? 121.814 152.400 198.430 1.00 92.79  ? 36  ASN B N   1 
ATOM   6106 C CA  . ASN D 4 54  ? 120.970 153.587 198.441 1.00 97.74  ? 36  ASN B CA  1 
ATOM   6107 C C   . ASN D 4 54  ? 121.759 154.866 198.191 1.00 99.36  ? 36  ASN B C   1 
ATOM   6108 O O   . ASN D 4 54  ? 121.217 155.960 198.387 1.00 102.80 ? 36  ASN B O   1 
ATOM   6109 C CB  . ASN D 4 54  ? 120.211 153.695 199.768 1.00 98.79  ? 36  ASN B CB  1 
ATOM   6110 C CG  . ASN D 4 54  ? 118.889 152.957 199.743 1.00 100.49 ? 36  ASN B CG  1 
ATOM   6111 O OD1 . ASN D 4 54  ? 118.552 152.298 198.759 1.00 101.06 ? 36  ASN B OD1 1 
ATOM   6112 N ND2 . ASN D 4 54  ? 118.132 153.062 200.829 1.00 100.19 ? 36  ASN B ND2 1 
ATOM   6113 N N   . ILE D 4 55  ? 123.008 154.762 197.769 1.00 85.57  ? 37  ILE B N   1 
ATOM   6114 C CA  . ILE D 4 55  ? 123.834 155.926 197.476 1.00 85.83  ? 37  ILE B CA  1 
ATOM   6115 C C   . ILE D 4 55  ? 123.815 156.187 195.977 1.00 84.23  ? 37  ILE B C   1 
ATOM   6116 O O   . ILE D 4 55  ? 123.960 155.264 195.166 1.00 88.04  ? 37  ILE B O   1 
ATOM   6117 C CB  . ILE D 4 55  ? 125.266 155.728 198.008 1.00 86.25  ? 37  ILE B CB  1 
ATOM   6118 C CG1 . ILE D 4 55  ? 126.156 156.913 197.633 1.00 85.32  ? 37  ILE B CG1 1 
ATOM   6119 C CG2 . ILE D 4 55  ? 125.848 154.409 197.538 1.00 87.28  ? 37  ILE B CG2 1 
ATOM   6120 C CD1 . ILE D 4 55  ? 127.536 156.845 198.240 1.00 86.74  ? 37  ILE B CD1 1 
ATOM   6121 N N   . ASP D 4 56  ? 123.612 157.449 195.608 1.00 82.39  ? 38  ASP B N   1 
ATOM   6122 C CA  . ASP D 4 56  ? 123.460 157.807 194.206 1.00 85.81  ? 38  ASP B CA  1 
ATOM   6123 C C   . ASP D 4 56  ? 124.753 157.535 193.440 1.00 84.59  ? 38  ASP B C   1 
ATOM   6124 O O   . ASP D 4 56  ? 125.844 157.848 193.928 1.00 83.99  ? 38  ASP B O   1 
ATOM   6125 C CB  . ASP D 4 56  ? 123.072 159.280 194.074 1.00 88.09  ? 38  ASP B CB  1 
ATOM   6126 C CG  . ASP D 4 56  ? 122.801 159.687 192.640 1.00 89.68  ? 38  ASP B CG  1 
ATOM   6127 O OD1 . ASP D 4 56  ? 121.689 159.410 192.143 1.00 89.08  ? 38  ASP B OD1 1 
ATOM   6128 O OD2 . ASP D 4 56  ? 123.697 160.286 192.009 1.00 89.30  ? 38  ASP B OD2 1 
ATOM   6129 N N   . PRO D 4 57  ? 124.665 156.958 192.245 1.00 76.81  ? 39  PRO B N   1 
ATOM   6130 C CA  . PRO D 4 57  ? 125.875 156.647 191.481 1.00 75.20  ? 39  PRO B CA  1 
ATOM   6131 C C   . PRO D 4 57  ? 126.581 157.902 190.996 1.00 76.67  ? 39  PRO B C   1 
ATOM   6132 O O   . PRO D 4 57  ? 125.993 158.978 190.865 1.00 79.55  ? 39  PRO B O   1 
ATOM   6133 C CB  . PRO D 4 57  ? 125.350 155.820 190.303 1.00 72.52  ? 39  PRO B CB  1 
ATOM   6134 C CG  . PRO D 4 57  ? 123.923 156.221 190.172 1.00 75.18  ? 39  PRO B CG  1 
ATOM   6135 C CD  . PRO D 4 57  ? 123.446 156.493 191.565 1.00 75.14  ? 39  PRO B CD  1 
ATOM   6136 N N   . VAL D 4 58  ? 127.879 157.745 190.727 1.00 78.23  ? 40  VAL B N   1 
ATOM   6137 C CA  . VAL D 4 58  ? 128.679 158.850 190.216 1.00 76.86  ? 40  VAL B CA  1 
ATOM   6138 C C   . VAL D 4 58  ? 128.316 159.185 188.775 1.00 78.50  ? 40  VAL B C   1 
ATOM   6139 O O   . VAL D 4 58  ? 128.745 160.221 188.255 1.00 77.32  ? 40  VAL B O   1 
ATOM   6140 C CB  . VAL D 4 58  ? 130.179 158.522 190.341 1.00 80.75  ? 40  VAL B CB  1 
ATOM   6141 C CG1 . VAL D 4 58  ? 130.621 157.604 189.211 1.00 83.63  ? 40  VAL B CG1 1 
ATOM   6142 C CG2 . VAL D 4 58  ? 131.010 159.794 190.370 1.00 82.54  ? 40  VAL B CG2 1 
ATOM   6143 N N   . GLY D 4 59  ? 127.530 158.338 188.116 1.00 93.03  ? 41  GLY B N   1 
ATOM   6144 C CA  . GLY D 4 59  ? 127.152 158.578 186.738 1.00 94.25  ? 41  GLY B CA  1 
ATOM   6145 C C   . GLY D 4 59  ? 128.293 158.352 185.770 1.00 95.39  ? 41  GLY B C   1 
ATOM   6146 O O   . GLY D 4 59  ? 129.052 157.389 185.909 1.00 98.17  ? 41  GLY B O   1 
ATOM   6147 N N   . ARG D 4 60  ? 128.425 159.232 184.783 1.00 94.08  ? 42  ARG B N   1 
ATOM   6148 C CA  . ARG D 4 60  ? 129.479 159.144 183.785 1.00 96.00  ? 42  ARG B CA  1 
ATOM   6149 C C   . ARG D 4 60  ? 130.433 160.314 183.964 1.00 95.12  ? 42  ARG B C   1 
ATOM   6150 O O   . ARG D 4 60  ? 129.996 161.459 184.118 1.00 97.27  ? 42  ARG B O   1 
ATOM   6151 C CB  . ARG D 4 60  ? 128.900 159.147 182.368 1.00 98.37  ? 42  ARG B CB  1 
ATOM   6152 C CG  . ARG D 4 60  ? 128.930 157.794 181.665 1.00 101.07 ? 42  ARG B CG  1 
ATOM   6153 C CD  . ARG D 4 60  ? 130.211 157.014 181.945 1.00 99.94  ? 42  ARG B CD  1 
ATOM   6154 N NE  . ARG D 4 60  ? 131.418 157.768 181.626 1.00 102.58 ? 42  ARG B NE  1 
ATOM   6155 C CZ  . ARG D 4 60  ? 131.860 157.998 180.397 1.00 103.26 ? 42  ARG B CZ  1 
ATOM   6156 N NH1 . ARG D 4 60  ? 131.215 157.549 179.334 1.00 100.66 ? 42  ARG B NH1 1 
ATOM   6157 N NH2 . ARG D 4 60  ? 132.983 158.692 180.232 1.00 101.64 ? 42  ARG B NH2 1 
ATOM   6158 N N   . ILE D 4 61  ? 131.731 160.024 183.952 1.00 88.13  ? 43  ILE B N   1 
ATOM   6159 C CA  . ILE D 4 61  ? 132.772 161.031 184.108 1.00 86.79  ? 43  ILE B CA  1 
ATOM   6160 C C   . ILE D 4 61  ? 133.740 160.907 182.939 1.00 82.61  ? 43  ILE B C   1 
ATOM   6161 O O   . ILE D 4 61  ? 134.058 159.798 182.494 1.00 84.68  ? 43  ILE B O   1 
ATOM   6162 C CB  . ILE D 4 61  ? 133.486 160.904 185.474 1.00 87.52  ? 43  ILE B CB  1 
ATOM   6163 C CG1 . ILE D 4 61  ? 134.658 159.930 185.422 1.00 84.46  ? 43  ILE B CG1 1 
ATOM   6164 C CG2 . ILE D 4 61  ? 132.509 160.481 186.564 1.00 87.54  ? 43  ILE B CG2 1 
ATOM   6165 C CD1 . ILE D 4 61  ? 135.525 160.009 186.642 1.00 86.99  ? 43  ILE B CD1 1 
ATOM   6166 N N   . GLN D 4 62  ? 134.169 162.054 182.409 1.00 85.85  ? 44  GLN B N   1 
ATOM   6167 C CA  . GLN D 4 62  ? 134.904 162.128 181.145 1.00 85.67  ? 44  GLN B CA  1 
ATOM   6168 C C   . GLN D 4 62  ? 136.156 162.978 181.341 1.00 88.18  ? 44  GLN B C   1 
ATOM   6169 O O   . GLN D 4 62  ? 136.081 164.209 181.334 1.00 89.35  ? 44  GLN B O   1 
ATOM   6170 C CB  . GLN D 4 62  ? 134.020 162.711 180.042 1.00 85.23  ? 44  GLN B CB  1 
ATOM   6171 C CG  . GLN D 4 62  ? 132.634 162.100 179.934 1.00 91.64  ? 44  GLN B CG  1 
ATOM   6172 C CD  . GLN D 4 62  ? 132.441 161.317 178.651 1.00 95.11  ? 44  GLN B CD  1 
ATOM   6173 O OE1 . GLN D 4 62  ? 133.270 161.376 177.744 1.00 93.32  ? 44  GLN B OE1 1 
ATOM   6174 N NE2 . GLN D 4 62  ? 131.336 160.584 178.566 1.00 91.88  ? 44  GLN B NE2 1 
ATOM   6175 N N   . MET D 4 63  ? 137.304 162.330 181.515 1.00 76.22  ? 45  MET B N   1 
ATOM   6176 C CA  . MET D 4 63  ? 138.561 163.058 181.497 1.00 74.46  ? 45  MET B CA  1 
ATOM   6177 C C   . MET D 4 63  ? 139.032 163.257 180.064 1.00 72.80  ? 45  MET B C   1 
ATOM   6178 O O   . MET D 4 63  ? 138.583 162.577 179.138 1.00 75.56  ? 45  MET B O   1 
ATOM   6179 C CB  . MET D 4 63  ? 139.646 162.331 182.291 1.00 75.04  ? 45  MET B CB  1 
ATOM   6180 C CG  . MET D 4 63  ? 139.549 162.505 183.793 1.00 79.06  ? 45  MET B CG  1 
ATOM   6181 S SD  . MET D 4 63  ? 139.828 160.954 184.657 1.00 88.03  ? 45  MET B SD  1 
ATOM   6182 C CE  . MET D 4 63  ? 138.215 160.212 184.507 1.00 82.07  ? 45  MET B CE  1 
ATOM   6183 N N   . ARG D 4 64  ? 139.945 164.207 179.888 1.00 70.75  ? 46  ARG B N   1 
ATOM   6184 C CA  . ARG D 4 64  ? 140.564 164.457 178.598 1.00 68.45  ? 46  ARG B CA  1 
ATOM   6185 C C   . ARG D 4 64  ? 142.043 164.741 178.806 1.00 68.03  ? 46  ARG B C   1 
ATOM   6186 O O   . ARG D 4 64  ? 142.480 165.105 179.904 1.00 77.00  ? 46  ARG B O   1 
ATOM   6187 C CB  . ARG D 4 64  ? 139.893 165.618 177.856 1.00 74.17  ? 46  ARG B CB  1 
ATOM   6188 C CG  . ARG D 4 64  ? 139.556 166.812 178.730 1.00 77.87  ? 46  ARG B CG  1 
ATOM   6189 C CD  . ARG D 4 64  ? 138.647 167.792 178.004 1.00 77.39  ? 46  ARG B CD  1 
ATOM   6190 N NE  . ARG D 4 64  ? 137.373 167.192 177.624 1.00 78.70  ? 46  ARG B NE  1 
ATOM   6191 C CZ  . ARG D 4 64  ? 137.087 166.742 176.410 1.00 77.83  ? 46  ARG B CZ  1 
ATOM   6192 N NH1 . ARG D 4 64  ? 137.967 166.804 175.424 1.00 74.48  ? 46  ARG B NH1 1 
ATOM   6193 N NH2 . ARG D 4 64  ? 135.888 166.216 176.179 1.00 78.07  ? 46  ARG B NH2 1 
ATOM   6194 N N   . THR D 4 65  ? 142.809 164.564 177.732 1.00 55.70  ? 47  THR B N   1 
ATOM   6195 C CA  . THR D 4 65  ? 144.259 164.709 177.775 1.00 59.61  ? 47  THR B CA  1 
ATOM   6196 C C   . THR D 4 65  ? 144.615 166.187 177.700 1.00 61.46  ? 47  THR B C   1 
ATOM   6197 O O   . THR D 4 65  ? 144.425 166.827 176.661 1.00 69.99  ? 47  THR B O   1 
ATOM   6198 C CB  . THR D 4 65  ? 144.912 163.939 176.631 1.00 61.05  ? 47  THR B CB  1 
ATOM   6199 O OG1 . THR D 4 65  ? 144.926 164.756 175.455 1.00 68.24  ? 47  THR B OG1 1 
ATOM   6200 C CG2 . THR D 4 65  ? 144.139 162.668 176.337 1.00 65.66  ? 47  THR B CG2 1 
ATOM   6201 N N   . ARG D 4 66  ? 145.135 166.731 178.797 1.00 58.90  ? 48  ARG B N   1 
ATOM   6202 C CA  . ARG D 4 66  ? 145.519 168.136 178.829 1.00 57.40  ? 48  ARG B CA  1 
ATOM   6203 C C   . ARG D 4 66  ? 146.950 168.357 178.357 1.00 56.84  ? 48  ARG B C   1 
ATOM   6204 O O   . ARG D 4 66  ? 147.232 169.360 177.694 1.00 58.23  ? 48  ARG B O   1 
ATOM   6205 C CB  . ARG D 4 66  ? 145.344 168.698 180.239 1.00 59.78  ? 48  ARG B CB  1 
ATOM   6206 C CG  . ARG D 4 66  ? 143.940 168.550 180.788 1.00 59.78  ? 48  ARG B CG  1 
ATOM   6207 C CD  . ARG D 4 66  ? 142.907 169.087 179.817 1.00 58.33  ? 48  ARG B CD  1 
ATOM   6208 N NE  . ARG D 4 66  ? 141.567 169.059 180.387 1.00 65.13  ? 48  ARG B NE  1 
ATOM   6209 C CZ  . ARG D 4 66  ? 140.613 169.934 180.102 1.00 67.98  ? 48  ARG B CZ  1 
ATOM   6210 N NH1 . ARG D 4 66  ? 140.819 170.928 179.254 1.00 63.72  ? 48  ARG B NH1 1 
ATOM   6211 N NH2 . ARG D 4 66  ? 139.425 169.812 180.685 1.00 67.73  ? 48  ARG B NH2 1 
ATOM   6212 N N   . ARG D 4 67  ? 147.859 167.443 178.684 1.00 66.87  ? 49  ARG B N   1 
ATOM   6213 C CA  . ARG D 4 67  ? 149.241 167.517 178.238 1.00 69.64  ? 49  ARG B CA  1 
ATOM   6214 C C   . ARG D 4 67  ? 149.698 166.159 177.733 1.00 71.51  ? 49  ARG B C   1 
ATOM   6215 O O   . ARG D 4 67  ? 149.169 165.118 178.130 1.00 80.64  ? 49  ARG B O   1 
ATOM   6216 C CB  . ARG D 4 67  ? 150.190 167.981 179.351 1.00 74.28  ? 49  ARG B CB  1 
ATOM   6217 C CG  . ARG D 4 67  ? 149.725 169.181 180.146 1.00 74.68  ? 49  ARG B CG  1 
ATOM   6218 C CD  . ARG D 4 67  ? 150.203 170.469 179.488 1.00 73.88  ? 49  ARG B CD  1 
ATOM   6219 N NE  . ARG D 4 67  ? 149.806 171.673 180.209 1.00 75.65  ? 49  ARG B NE  1 
ATOM   6220 C CZ  . ARG D 4 67  ? 148.555 172.036 180.463 1.00 73.99  ? 49  ARG B CZ  1 
ATOM   6221 N NH1 . ARG D 4 67  ? 147.524 171.335 180.022 1.00 77.03  ? 49  ARG B NH1 1 
ATOM   6222 N NH2 . ARG D 4 67  ? 148.333 173.142 181.164 1.00 70.40  ? 49  ARG B NH2 1 
ATOM   6223 N N   . THR D 4 68  ? 150.690 166.185 176.848 1.00 68.43  ? 50  THR B N   1 
ATOM   6224 C CA  . THR D 4 68  ? 151.339 164.979 176.356 1.00 70.47  ? 50  THR B CA  1 
ATOM   6225 C C   . THR D 4 68  ? 152.835 165.234 176.267 1.00 69.44  ? 50  THR B C   1 
ATOM   6226 O O   . THR D 4 68  ? 153.271 166.161 175.579 1.00 74.31  ? 50  THR B O   1 
ATOM   6227 C CB  . THR D 4 68  ? 150.776 164.556 174.992 1.00 73.37  ? 50  THR B CB  1 
ATOM   6228 O OG1 . THR D 4 68  ? 151.642 163.586 174.391 1.00 71.49  ? 50  THR B OG1 1 
ATOM   6229 C CG2 . THR D 4 68  ? 150.616 165.759 174.064 1.00 74.70  ? 50  THR B CG2 1 
ATOM   6230 N N   . LEU D 4 69  ? 153.615 164.425 176.976 1.00 65.75  ? 51  LEU B N   1 
ATOM   6231 C CA  . LEU D 4 69  ? 155.063 164.566 177.029 1.00 69.31  ? 51  LEU B CA  1 
ATOM   6232 C C   . LEU D 4 69  ? 155.709 163.387 176.315 1.00 73.10  ? 51  LEU B C   1 
ATOM   6233 O O   . LEU D 4 69  ? 155.423 162.229 176.635 1.00 81.39  ? 51  LEU B O   1 
ATOM   6234 C CB  . LEU D 4 69  ? 155.542 164.674 178.478 1.00 72.66  ? 51  LEU B CB  1 
ATOM   6235 C CG  . LEU D 4 69  ? 154.691 165.623 179.334 1.00 76.67  ? 51  LEU B CG  1 
ATOM   6236 C CD1 . LEU D 4 69  ? 153.789 164.878 180.299 1.00 72.59  ? 51  LEU B CD1 1 
ATOM   6237 C CD2 . LEU D 4 69  ? 155.552 166.631 180.081 1.00 74.04  ? 51  LEU B CD2 1 
ATOM   6238 N N   . ARG D 4 70  ? 156.583 163.687 175.356 1.00 73.05  ? 52  ARG B N   1 
ATOM   6239 C CA  . ARG D 4 70  ? 157.007 162.733 174.337 1.00 76.51  ? 52  ARG B CA  1 
ATOM   6240 C C   . ARG D 4 70  ? 158.525 162.660 174.228 1.00 79.32  ? 52  ARG B C   1 
ATOM   6241 O O   . ARG D 4 70  ? 159.077 162.315 173.179 1.00 85.03  ? 52  ARG B O   1 
ATOM   6242 C CB  . ARG D 4 70  ? 156.374 163.093 172.994 1.00 77.50  ? 52  ARG B CB  1 
ATOM   6243 C CG  . ARG D 4 70  ? 156.980 164.314 172.314 1.00 81.60  ? 52  ARG B CG  1 
ATOM   6244 C CD  . ARG D 4 70  ? 156.138 164.772 171.136 1.00 82.90  ? 52  ARG B CD  1 
ATOM   6245 N NE  . ARG D 4 70  ? 154.734 164.924 171.499 1.00 82.67  ? 52  ARG B NE  1 
ATOM   6246 C CZ  . ARG D 4 70  ? 153.723 164.394 170.825 1.00 83.30  ? 52  ARG B CZ  1 
ATOM   6247 N NH1 . ARG D 4 70  ? 153.923 163.663 169.741 1.00 83.05  ? 52  ARG B NH1 1 
ATOM   6248 N NH2 . ARG D 4 70  ? 152.480 164.602 171.249 1.00 82.19  ? 52  ARG B NH2 1 
ATOM   6249 N N   . GLY D 4 71  ? 159.228 162.941 175.319 1.00 79.31  ? 53  GLY B N   1 
ATOM   6250 C CA  . GLY D 4 71  ? 160.677 162.977 175.276 1.00 84.09  ? 53  GLY B CA  1 
ATOM   6251 C C   . GLY D 4 71  ? 161.370 161.629 175.210 1.00 82.87  ? 53  GLY B C   1 
ATOM   6252 O O   . GLY D 4 71  ? 162.494 161.534 174.709 1.00 81.63  ? 53  GLY B O   1 
ATOM   6253 N N   . HIS D 4 72  ? 160.719 160.581 175.707 1.00 70.08  ? 54  HIS B N   1 
ATOM   6254 C CA  . HIS D 4 72  ? 161.368 159.282 175.805 1.00 69.57  ? 54  HIS B CA  1 
ATOM   6255 C C   . HIS D 4 72  ? 161.501 158.626 174.433 1.00 73.97  ? 54  HIS B C   1 
ATOM   6256 O O   . HIS D 4 72  ? 160.806 158.973 173.474 1.00 73.00  ? 54  HIS B O   1 
ATOM   6257 C CB  . HIS D 4 72  ? 160.595 158.366 176.753 1.00 74.15  ? 54  HIS B CB  1 
ATOM   6258 C CG  . HIS D 4 72  ? 160.924 158.583 178.197 1.00 77.23  ? 54  HIS B CG  1 
ATOM   6259 N ND1 . HIS D 4 72  ? 162.189 158.394 178.706 1.00 74.26  ? 54  HIS B ND1 1 
ATOM   6260 C CD2 . HIS D 4 72  ? 160.155 158.981 179.237 1.00 76.73  ? 54  HIS B CD2 1 
ATOM   6261 C CE1 . HIS D 4 72  ? 162.185 158.661 179.999 1.00 73.11  ? 54  HIS B CE1 1 
ATOM   6262 N NE2 . HIS D 4 72  ? 160.963 159.020 180.347 1.00 72.49  ? 54  HIS B NE2 1 
ATOM   6263 N N   . LEU D 4 73  ? 162.419 157.660 174.352 1.00 72.75  ? 55  LEU B N   1 
ATOM   6264 C CA  . LEU D 4 73  ? 162.715 156.962 173.106 1.00 71.41  ? 55  LEU B CA  1 
ATOM   6265 C C   . LEU D 4 73  ? 162.594 155.448 173.241 1.00 69.19  ? 55  LEU B C   1 
ATOM   6266 O O   . LEU D 4 73  ? 163.079 154.714 172.375 1.00 71.59  ? 55  LEU B O   1 
ATOM   6267 C CB  . LEU D 4 73  ? 164.112 157.337 172.609 1.00 69.31  ? 55  LEU B CB  1 
ATOM   6268 C CG  . LEU D 4 73  ? 164.179 158.500 171.618 1.00 74.89  ? 55  LEU B CG  1 
ATOM   6269 C CD1 . LEU D 4 73  ? 165.575 158.636 171.043 1.00 69.84  ? 55  LEU B CD1 1 
ATOM   6270 C CD2 . LEU D 4 73  ? 163.156 158.319 170.508 1.00 76.84  ? 55  LEU B CD2 1 
ATOM   6271 N N   . ALA D 4 74  ? 161.959 154.963 174.303 1.00 73.24  ? 56  ALA B N   1 
ATOM   6272 C CA  . ALA D 4 74  ? 161.828 153.529 174.527 1.00 71.98  ? 56  ALA B CA  1 
ATOM   6273 C C   . ALA D 4 74  ? 160.631 153.296 175.446 1.00 77.00  ? 56  ALA B C   1 
ATOM   6274 O O   . ALA D 4 74  ? 159.821 154.204 175.666 1.00 80.93  ? 56  ALA B O   1 
ATOM   6275 C CB  . ALA D 4 74  ? 163.136 152.951 175.091 1.00 69.11  ? 56  ALA B CB  1 
ATOM   6276 N N   . LYS D 4 75  ? 160.518 152.083 175.980 1.00 71.43  ? 57  LYS B N   1 
ATOM   6277 C CA  . LYS D 4 75  ? 159.398 151.730 176.840 1.00 70.17  ? 57  LYS B CA  1 
ATOM   6278 C C   . LYS D 4 75  ? 159.537 152.380 178.211 1.00 74.87  ? 57  LYS B C   1 
ATOM   6279 O O   . LYS D 4 75  ? 160.636 152.473 178.764 1.00 80.65  ? 57  LYS B O   1 
ATOM   6280 C CB  . LYS D 4 75  ? 159.301 150.213 176.988 1.00 69.91  ? 57  LYS B CB  1 
ATOM   6281 C CG  . LYS D 4 75  ? 158.653 149.517 175.806 1.00 71.47  ? 57  LYS B CG  1 
ATOM   6282 C CD  . LYS D 4 75  ? 158.467 148.034 176.069 1.00 76.11  ? 57  LYS B CD  1 
ATOM   6283 C CE  . LYS D 4 75  ? 159.793 147.295 176.051 1.00 77.75  ? 57  LYS B CE  1 
ATOM   6284 N NZ  . LYS D 4 75  ? 160.531 147.515 174.777 1.00 75.15  ? 57  LYS B NZ  1 
ATOM   6285 N N   . ILE D 4 76  ? 158.412 152.826 178.756 1.00 71.56  ? 58  ILE B N   1 
ATOM   6286 C CA  . ILE D 4 76  ? 158.369 153.480 180.058 1.00 72.30  ? 58  ILE B CA  1 
ATOM   6287 C C   . ILE D 4 76  ? 157.927 152.459 181.097 1.00 77.61  ? 58  ILE B C   1 
ATOM   6288 O O   . ILE D 4 76  ? 156.899 151.794 180.924 1.00 81.41  ? 58  ILE B O   1 
ATOM   6289 C CB  . ILE D 4 76  ? 157.417 154.687 180.027 1.00 66.88  ? 58  ILE B CB  1 
ATOM   6290 C CG1 . ILE D 4 76  ? 158.158 155.940 179.567 1.00 71.59  ? 58  ILE B CG1 1 
ATOM   6291 C CG2 . ILE D 4 76  ? 156.790 154.924 181.390 1.00 68.07  ? 58  ILE B CG2 1 
ATOM   6292 C CD1 . ILE D 4 76  ? 157.290 157.169 179.538 1.00 76.79  ? 58  ILE B CD1 1 
ATOM   6293 N N   . TYR D 4 77  ? 158.700 152.322 182.176 1.00 79.66  ? 59  TYR B N   1 
ATOM   6294 C CA  . TYR D 4 77  ? 158.351 151.338 183.197 1.00 72.40  ? 59  TYR B CA  1 
ATOM   6295 C C   . TYR D 4 77  ? 157.727 151.938 184.450 1.00 75.28  ? 59  TYR B C   1 
ATOM   6296 O O   . TYR D 4 77  ? 156.705 151.431 184.920 1.00 78.89  ? 59  TYR B O   1 
ATOM   6297 C CB  . TYR D 4 77  ? 159.575 150.510 183.593 1.00 72.65  ? 59  TYR B CB  1 
ATOM   6298 C CG  . TYR D 4 77  ? 159.908 149.404 182.620 1.00 76.11  ? 59  TYR B CG  1 
ATOM   6299 C CD1 . TYR D 4 77  ? 159.110 148.271 182.535 1.00 80.08  ? 59  TYR B CD1 1 
ATOM   6300 C CD2 . TYR D 4 77  ? 161.024 149.480 181.803 1.00 76.22  ? 59  TYR B CD2 1 
ATOM   6301 C CE1 . TYR D 4 77  ? 159.408 147.253 181.655 1.00 78.54  ? 59  TYR B CE1 1 
ATOM   6302 C CE2 . TYR D 4 77  ? 161.328 148.464 180.924 1.00 75.24  ? 59  TYR B CE2 1 
ATOM   6303 C CZ  . TYR D 4 77  ? 160.519 147.355 180.852 1.00 77.13  ? 59  TYR B CZ  1 
ATOM   6304 O OH  . TYR D 4 77  ? 160.822 146.342 179.974 1.00 77.80  ? 59  TYR B OH  1 
ATOM   6305 N N   . ALA D 4 78  ? 158.302 152.997 185.010 1.00 72.35  ? 60  ALA B N   1 
ATOM   6306 C CA  . ALA D 4 78  ? 157.855 153.505 186.297 1.00 74.63  ? 60  ALA B CA  1 
ATOM   6307 C C   . ALA D 4 78  ? 157.637 155.010 186.235 1.00 77.17  ? 60  ALA B C   1 
ATOM   6308 O O   . ALA D 4 78  ? 158.209 155.713 185.399 1.00 83.91  ? 60  ALA B O   1 
ATOM   6309 C CB  . ALA D 4 78  ? 158.859 153.173 187.409 1.00 78.03  ? 60  ALA B CB  1 
ATOM   6310 N N   . MET D 4 79  ? 156.793 155.491 187.144 1.00 68.16  ? 61  MET B N   1 
ATOM   6311 C CA  . MET D 4 79  ? 156.539 156.913 187.309 1.00 64.30  ? 61  MET B CA  1 
ATOM   6312 C C   . MET D 4 79  ? 156.122 157.169 188.748 1.00 71.65  ? 61  MET B C   1 
ATOM   6313 O O   . MET D 4 79  ? 155.626 156.271 189.432 1.00 77.16  ? 61  MET B O   1 
ATOM   6314 C CB  . MET D 4 79  ? 155.461 157.408 186.339 1.00 62.16  ? 61  MET B CB  1 
ATOM   6315 C CG  . MET D 4 79  ? 154.049 156.994 186.705 1.00 70.72  ? 61  MET B CG  1 
ATOM   6316 S SD  . MET D 4 79  ? 153.204 158.187 187.755 1.00 89.15  ? 61  MET B SD  1 
ATOM   6317 C CE  . MET D 4 79  ? 152.961 159.512 186.588 1.00 69.37  ? 61  MET B CE  1 
ATOM   6318 N N   . HIS D 4 80  ? 156.326 158.404 189.205 1.00 67.70  ? 62  HIS B N   1 
ATOM   6319 C CA  . HIS D 4 80  ? 155.908 158.779 190.550 1.00 64.11  ? 62  HIS B CA  1 
ATOM   6320 C C   . HIS D 4 80  ? 155.694 160.282 190.616 1.00 67.30  ? 62  HIS B C   1 
ATOM   6321 O O   . HIS D 4 80  ? 156.556 161.053 190.186 1.00 75.56  ? 62  HIS B O   1 
ATOM   6322 C CB  . HIS D 4 80  ? 156.937 158.343 191.595 1.00 67.23  ? 62  HIS B CB  1 
ATOM   6323 C CG  . HIS D 4 80  ? 156.364 158.175 192.967 1.00 69.62  ? 62  HIS B CG  1 
ATOM   6324 N ND1 . HIS D 4 80  ? 156.765 158.936 194.042 1.00 75.45  ? 62  HIS B ND1 1 
ATOM   6325 C CD2 . HIS D 4 80  ? 155.410 157.336 193.436 1.00 70.21  ? 62  HIS B CD2 1 
ATOM   6326 C CE1 . HIS D 4 80  ? 156.088 158.571 195.116 1.00 72.48  ? 62  HIS B CE1 1 
ATOM   6327 N NE2 . HIS D 4 80  ? 155.258 157.602 194.774 1.00 69.87  ? 62  HIS B NE2 1 
ATOM   6328 N N   . TRP D 4 81  ? 154.549 160.688 191.157 1.00 64.25  ? 63  TRP B N   1 
ATOM   6329 C CA  . TRP D 4 81  ? 154.237 162.098 191.337 1.00 60.10  ? 63  TRP B CA  1 
ATOM   6330 C C   . TRP D 4 81  ? 154.995 162.670 192.526 1.00 65.90  ? 63  TRP B C   1 
ATOM   6331 O O   . TRP D 4 81  ? 155.191 161.995 193.540 1.00 67.59  ? 63  TRP B O   1 
ATOM   6332 C CB  . TRP D 4 81  ? 152.737 162.287 191.553 1.00 58.28  ? 63  TRP B CB  1 
ATOM   6333 C CG  . TRP D 4 81  ? 151.962 162.532 190.307 1.00 59.64  ? 63  TRP B CG  1 
ATOM   6334 C CD1 . TRP D 4 81  ? 151.157 161.647 189.660 1.00 62.74  ? 63  TRP B CD1 1 
ATOM   6335 C CD2 . TRP D 4 81  ? 151.893 163.754 189.567 1.00 62.20  ? 63  TRP B CD2 1 
ATOM   6336 N NE1 . TRP D 4 81  ? 150.599 162.237 188.555 1.00 63.55  ? 63  TRP B NE1 1 
ATOM   6337 C CE2 . TRP D 4 81  ? 151.036 163.532 188.476 1.00 61.67  ? 63  TRP B CE2 1 
ATOM   6338 C CE3 . TRP D 4 81  ? 152.478 165.014 189.720 1.00 68.57  ? 63  TRP B CE3 1 
ATOM   6339 C CZ2 . TRP D 4 81  ? 150.748 164.520 187.542 1.00 64.33  ? 63  TRP B CZ2 1 
ATOM   6340 C CZ3 . TRP D 4 81  ? 152.190 165.993 188.790 1.00 66.93  ? 63  TRP B CZ3 1 
ATOM   6341 C CH2 . TRP D 4 81  ? 151.332 165.741 187.716 1.00 63.88  ? 63  TRP B CH2 1 
ATOM   6342 N N   . GLY D 4 82  ? 155.420 163.921 192.397 1.00 72.61  ? 64  GLY B N   1 
ATOM   6343 C CA  . GLY D 4 82  ? 156.019 164.618 193.512 1.00 69.61  ? 64  GLY B CA  1 
ATOM   6344 C C   . GLY D 4 82  ? 154.983 165.064 194.522 1.00 73.17  ? 64  GLY B C   1 
ATOM   6345 O O   . GLY D 4 82  ? 153.775 164.984 194.298 1.00 79.47  ? 64  GLY B O   1 
ATOM   6346 N N   . THR D 4 83  ? 155.472 165.547 195.663 1.00 68.87  ? 65  THR B N   1 
ATOM   6347 C CA  . THR D 4 83  ? 154.574 165.972 196.728 1.00 67.67  ? 65  THR B CA  1 
ATOM   6348 C C   . THR D 4 83  ? 153.931 167.324 196.451 1.00 69.23  ? 65  THR B C   1 
ATOM   6349 O O   . THR D 4 83  ? 152.940 167.667 197.104 1.00 74.27  ? 65  THR B O   1 
ATOM   6350 C CB  . THR D 4 83  ? 155.318 166.029 198.061 1.00 72.22  ? 65  THR B CB  1 
ATOM   6351 O OG1 . THR D 4 83  ? 154.391 166.326 199.111 1.00 72.75  ? 65  THR B OG1 1 
ATOM   6352 C CG2 . THR D 4 83  ? 156.389 167.106 198.020 1.00 72.91  ? 65  THR B CG2 1 
ATOM   6353 N N   . ASP D 4 84  ? 154.465 168.093 195.506 1.00 74.41  ? 66  ASP B N   1 
ATOM   6354 C CA  . ASP D 4 84  ? 153.923 169.399 195.163 1.00 74.33  ? 66  ASP B CA  1 
ATOM   6355 C C   . ASP D 4 84  ? 152.930 169.346 194.012 1.00 72.11  ? 66  ASP B C   1 
ATOM   6356 O O   . ASP D 4 84  ? 152.412 170.395 193.614 1.00 73.88  ? 66  ASP B O   1 
ATOM   6357 C CB  . ASP D 4 84  ? 155.059 170.367 194.821 1.00 78.40  ? 66  ASP B CB  1 
ATOM   6358 C CG  . ASP D 4 84  ? 156.101 169.746 193.913 1.00 82.69  ? 66  ASP B CG  1 
ATOM   6359 O OD1 . ASP D 4 84  ? 155.738 168.893 193.077 1.00 87.02  ? 66  ASP B OD1 1 
ATOM   6360 O OD2 . ASP D 4 84  ? 157.289 170.111 194.037 1.00 83.00  ? 66  ASP B OD2 1 
ATOM   6361 N N   . SER D 4 85  ? 152.658 168.158 193.471 1.00 68.46  ? 67  SER B N   1 
ATOM   6362 C CA  . SER D 4 85  ? 151.709 167.975 192.374 1.00 67.44  ? 67  SER B CA  1 
ATOM   6363 C C   . SER D 4 85  ? 152.074 168.816 191.155 1.00 70.14  ? 67  SER B C   1 
ATOM   6364 O O   . SER D 4 85  ? 151.197 169.320 190.450 1.00 72.61  ? 67  SER B O   1 
ATOM   6365 C CB  . SER D 4 85  ? 150.278 168.279 192.823 1.00 71.88  ? 67  SER B CB  1 
ATOM   6366 O OG  . SER D 4 85  ? 149.951 167.555 193.995 1.00 75.89  ? 67  SER B OG  1 
ATOM   6367 N N   . ARG D 4 86  ? 153.371 168.977 190.895 1.00 64.76  ? 68  ARG B N   1 
ATOM   6368 C CA  . ARG D 4 86  ? 153.817 169.748 189.742 1.00 65.31  ? 68  ARG B CA  1 
ATOM   6369 C C   . ARG D 4 86  ? 154.935 169.037 188.989 1.00 66.81  ? 68  ARG B C   1 
ATOM   6370 O O   . ARG D 4 86  ? 155.178 169.328 187.815 1.00 80.08  ? 68  ARG B O   1 
ATOM   6371 C CB  . ARG D 4 86  ? 154.281 171.137 190.180 1.00 66.71  ? 68  ARG B CB  1 
ATOM   6372 C CG  . ARG D 4 86  ? 153.891 172.253 189.227 1.00 72.21  ? 68  ARG B CG  1 
ATOM   6373 C CD  . ARG D 4 86  ? 154.191 173.615 189.834 1.00 73.61  ? 68  ARG B CD  1 
ATOM   6374 N NE  . ARG D 4 86  ? 153.928 174.717 188.915 1.00 69.64  ? 68  ARG B NE  1 
ATOM   6375 C CZ  . ARG D 4 86  ? 154.639 174.983 187.827 1.00 69.01  ? 68  ARG B CZ  1 
ATOM   6376 N NH1 . ARG D 4 86  ? 155.687 174.251 187.487 1.00 69.95  ? 68  ARG B NH1 1 
ATOM   6377 N NH2 . ARG D 4 86  ? 154.294 176.016 187.065 1.00 67.60  ? 68  ARG B NH2 1 
ATOM   6378 N N   . LEU D 4 87  ? 155.620 168.109 189.650 1.00 54.75  ? 69  LEU B N   1 
ATOM   6379 C CA  . LEU D 4 87  ? 156.798 167.461 189.095 1.00 59.12  ? 69  LEU B CA  1 
ATOM   6380 C C   . LEU D 4 87  ? 156.557 165.970 188.894 1.00 64.19  ? 69  LEU B C   1 
ATOM   6381 O O   . LEU D 4 87  ? 155.772 165.348 189.614 1.00 69.28  ? 69  LEU B O   1 
ATOM   6382 C CB  . LEU D 4 87  ? 158.009 167.671 190.006 1.00 61.88  ? 69  LEU B CB  1 
ATOM   6383 C CG  . LEU D 4 87  ? 158.510 169.110 190.134 1.00 59.41  ? 69  LEU B CG  1 
ATOM   6384 C CD1 . LEU D 4 87  ? 159.256 169.299 191.442 1.00 66.15  ? 69  LEU B CD1 1 
ATOM   6385 C CD2 . LEU D 4 87  ? 159.395 169.473 188.959 1.00 59.55  ? 69  LEU B CD2 1 
ATOM   6386 N N   . LEU D 4 88  ? 157.244 165.402 187.903 1.00 64.21  ? 70  LEU B N   1 
ATOM   6387 C CA  . LEU D 4 88  ? 157.137 163.984 187.585 1.00 59.58  ? 70  LEU B CA  1 
ATOM   6388 C C   . LEU D 4 88  ? 158.520 163.390 187.376 1.00 65.49  ? 70  LEU B C   1 
ATOM   6389 O O   . LEU D 4 88  ? 159.451 164.084 186.964 1.00 72.73  ? 70  LEU B O   1 
ATOM   6390 C CB  . LEU D 4 88  ? 156.313 163.741 186.319 1.00 59.80  ? 70  LEU B CB  1 
ATOM   6391 C CG  . LEU D 4 88  ? 154.795 163.772 186.411 1.00 69.61  ? 70  LEU B CG  1 
ATOM   6392 C CD1 . LEU D 4 88  ? 154.300 165.149 186.032 1.00 67.07  ? 70  LEU B CD1 1 
ATOM   6393 C CD2 . LEU D 4 88  ? 154.203 162.725 185.495 1.00 70.20  ? 70  LEU B CD2 1 
ATOM   6394 N N   . VAL D 4 89  ? 158.636 162.090 187.634 1.00 61.30  ? 71  VAL B N   1 
ATOM   6395 C CA  . VAL D 4 89  ? 159.847 161.329 187.349 1.00 59.96  ? 71  VAL B CA  1 
ATOM   6396 C C   . VAL D 4 89  ? 159.455 160.088 186.557 1.00 64.46  ? 71  VAL B C   1 
ATOM   6397 O O   . VAL D 4 89  ? 158.398 159.494 186.798 1.00 66.01  ? 71  VAL B O   1 
ATOM   6398 C CB  . VAL D 4 89  ? 160.611 160.963 188.640 1.00 57.29  ? 71  VAL B CB  1 
ATOM   6399 C CG1 . VAL D 4 89  ? 159.895 159.868 189.416 1.00 63.39  ? 71  VAL B CG1 1 
ATOM   6400 C CG2 . VAL D 4 89  ? 162.035 160.552 188.318 1.00 65.05  ? 71  VAL B CG2 1 
ATOM   6401 N N   . SER D 4 90  ? 160.284 159.721 185.582 1.00 74.28  ? 72  SER B N   1 
ATOM   6402 C CA  . SER D 4 90  ? 159.965 158.598 184.710 1.00 72.46  ? 72  SER B CA  1 
ATOM   6403 C C   . SER D 4 90  ? 161.234 157.850 184.329 1.00 74.92  ? 72  SER B C   1 
ATOM   6404 O O   . SER D 4 90  ? 162.280 158.465 184.100 1.00 83.43  ? 72  SER B O   1 
ATOM   6405 C CB  . SER D 4 90  ? 159.235 159.070 183.450 1.00 73.82  ? 72  SER B CB  1 
ATOM   6406 O OG  . SER D 4 90  ? 157.836 159.090 183.660 1.00 82.81  ? 72  SER B OG  1 
ATOM   6407 N N   . ALA D 4 91  ? 161.126 156.524 184.250 1.00 62.64  ? 73  ALA B N   1 
ATOM   6408 C CA  . ALA D 4 91  ? 162.243 155.641 183.937 1.00 61.95  ? 73  ALA B CA  1 
ATOM   6409 C C   . ALA D 4 91  ? 161.966 154.904 182.636 1.00 64.34  ? 73  ALA B C   1 
ATOM   6410 O O   . ALA D 4 91  ? 160.881 154.332 182.459 1.00 70.15  ? 73  ALA B O   1 
ATOM   6411 C CB  . ALA D 4 91  ? 162.480 154.635 185.064 1.00 64.00  ? 73  ALA B CB  1 
ATOM   6412 N N   . SER D 4 92  ? 162.944 154.912 181.731 1.00 70.17  ? 74  SER B N   1 
ATOM   6413 C CA  . SER D 4 92  ? 162.759 154.287 180.425 1.00 71.13  ? 74  SER B CA  1 
ATOM   6414 C C   . SER D 4 92  ? 163.626 153.039 180.270 1.00 69.44  ? 74  SER B C   1 
ATOM   6415 O O   . SER D 4 92  ? 164.191 152.518 181.233 1.00 72.27  ? 74  SER B O   1 
ATOM   6416 C CB  . SER D 4 92  ? 162.880 155.321 179.304 1.00 77.95  ? 74  SER B CB  1 
ATOM   6417 O OG  . SER D 4 92  ? 163.998 156.168 179.510 1.00 84.77  ? 74  SER B OG  1 
ATOM   6418 N N   . GLN D 4 93  ? 163.729 152.568 179.025 1.00 77.46  ? 75  GLN B N   1 
ATOM   6419 C CA  . GLN D 4 93  ? 164.522 151.391 178.687 1.00 78.25  ? 75  GLN B CA  1 
ATOM   6420 C C   . GLN D 4 93  ? 165.851 151.887 178.136 1.00 78.39  ? 75  GLN B C   1 
ATOM   6421 O O   . GLN D 4 93  ? 166.283 151.465 177.059 1.00 84.61  ? 75  GLN B O   1 
ATOM   6422 C CB  . GLN D 4 93  ? 163.843 150.494 177.651 1.00 82.91  ? 75  GLN B CB  1 
ATOM   6423 C CG  . GLN D 4 93  ? 163.177 149.266 178.223 1.00 80.46  ? 75  GLN B CG  1 
ATOM   6424 C CD  . GLN D 4 93  ? 164.179 148.294 178.812 1.00 84.86  ? 75  GLN B CD  1 
ATOM   6425 O OE1 . GLN D 4 93  ? 164.254 148.119 180.027 1.00 82.05  ? 75  GLN B OE1 1 
ATOM   6426 N NE2 . GLN D 4 93  ? 164.957 147.655 177.947 1.00 84.64  ? 75  GLN B NE2 1 
ATOM   6427 N N   . ASP D 4 94  ? 166.500 152.775 178.876 1.00 79.49  ? 76  ASP B N   1 
ATOM   6428 C CA  . ASP D 4 94  ? 167.845 153.248 178.579 1.00 82.28  ? 76  ASP B CA  1 
ATOM   6429 C C   . ASP D 4 94  ? 168.323 154.014 179.805 1.00 88.19  ? 76  ASP B C   1 
ATOM   6430 O O   . ASP D 4 94  ? 167.645 154.043 180.837 1.00 90.75  ? 76  ASP B O   1 
ATOM   6431 C CB  . ASP D 4 94  ? 167.875 154.105 177.308 1.00 80.01  ? 76  ASP B CB  1 
ATOM   6432 C CG  . ASP D 4 94  ? 167.016 155.345 177.418 1.00 86.39  ? 76  ASP B CG  1 
ATOM   6433 O OD1 . ASP D 4 94  ? 166.335 155.509 178.448 1.00 88.45  ? 76  ASP B OD1 1 
ATOM   6434 O OD2 . ASP D 4 94  ? 167.022 156.158 176.470 1.00 92.32  ? 76  ASP B OD2 1 
ATOM   6435 N N   . GLY D 4 95  ? 169.488 154.640 179.699 1.00 85.71  ? 77  GLY B N   1 
ATOM   6436 C CA  . GLY D 4 95  ? 169.953 155.473 180.787 1.00 86.17  ? 77  GLY B CA  1 
ATOM   6437 C C   . GLY D 4 95  ? 169.104 156.710 180.588 1.00 83.76  ? 77  GLY B C   1 
ATOM   6438 O O   . GLY D 4 95  ? 169.518 157.647 179.900 1.00 83.06  ? 77  GLY B O   1 
ATOM   6439 N N   . LYS D 4 96  ? 167.912 156.725 181.183 1.00 71.88  ? 78  LYS B N   1 
ATOM   6440 C CA  . LYS D 4 96  ? 166.931 157.785 180.960 1.00 65.48  ? 78  LYS B CA  1 
ATOM   6441 C C   . LYS D 4 96  ? 166.035 157.792 182.195 1.00 66.04  ? 78  LYS B C   1 
ATOM   6442 O O   . LYS D 4 96  ? 165.069 157.018 182.288 1.00 72.14  ? 78  LYS B O   1 
ATOM   6443 C CB  . LYS D 4 96  ? 166.106 157.765 179.677 1.00 73.58  ? 78  LYS B CB  1 
ATOM   6444 C CG  . LYS D 4 96  ? 166.883 158.188 178.437 1.00 81.42  ? 78  LYS B CG  1 
ATOM   6445 C CD  . LYS D 4 96  ? 167.908 159.262 178.769 1.00 78.63  ? 78  LYS B CD  1 
ATOM   6446 C CE  . LYS D 4 96  ? 169.121 159.179 177.859 1.00 75.53  ? 78  LYS B CE  1 
ATOM   6447 N NZ  . LYS D 4 96  ? 170.220 160.068 178.321 1.00 73.44  ? 78  LYS B NZ  1 
ATOM   6448 N N   . LEU D 4 97  ? 166.374 158.678 183.135 1.00 53.59  ? 79  LEU B N   1 
ATOM   6449 C CA  . LEU D 4 97  ? 165.518 159.054 184.257 1.00 55.22  ? 79  LEU B CA  1 
ATOM   6450 C C   . LEU D 4 97  ? 165.170 160.523 184.047 1.00 63.15  ? 79  LEU B C   1 
ATOM   6451 O O   . LEU D 4 97  ? 166.009 161.399 184.269 1.00 70.69  ? 79  LEU B O   1 
ATOM   6452 C CB  . LEU D 4 97  ? 166.228 158.842 185.589 1.00 61.52  ? 79  LEU B CB  1 
ATOM   6453 C CG  . LEU D 4 97  ? 165.400 158.268 186.733 1.00 60.75  ? 79  LEU B CG  1 
ATOM   6454 C CD1 . LEU D 4 97  ? 164.975 156.864 186.380 1.00 62.62  ? 79  LEU B CD1 1 
ATOM   6455 C CD2 . LEU D 4 97  ? 166.186 158.286 188.029 1.00 59.66  ? 79  LEU B CD2 1 
ATOM   6456 N N   . ILE D 4 98  ? 163.949 160.806 183.616 1.00 63.09  ? 80  ILE B N   1 
ATOM   6457 C CA  . ILE D 4 98  ? 163.567 162.159 183.226 1.00 57.49  ? 80  ILE B CA  1 
ATOM   6458 C C   . ILE D 4 98  ? 162.672 162.751 184.304 1.00 62.32  ? 80  ILE B C   1 
ATOM   6459 O O   . ILE D 4 98  ? 161.707 162.111 184.741 1.00 69.58  ? 80  ILE B O   1 
ATOM   6460 C CB  . ILE D 4 98  ? 162.856 162.169 181.865 1.00 59.15  ? 80  ILE B CB  1 
ATOM   6461 C CG1 . ILE D 4 98  ? 163.859 161.975 180.735 1.00 62.65  ? 80  ILE B CG1 1 
ATOM   6462 C CG2 . ILE D 4 98  ? 162.182 163.502 181.655 1.00 62.70  ? 80  ILE B CG2 1 
ATOM   6463 C CD1 . ILE D 4 98  ? 163.272 162.245 179.377 1.00 64.68  ? 80  ILE B CD1 1 
ATOM   6464 N N   . ILE D 4 99  ? 162.991 163.969 184.732 1.00 59.78  ? 81  ILE B N   1 
ATOM   6465 C CA  . ILE D 4 99  ? 162.172 164.728 185.670 1.00 56.98  ? 81  ILE B CA  1 
ATOM   6466 C C   . ILE D 4 99  ? 161.522 165.865 184.896 1.00 63.31  ? 81  ILE B C   1 
ATOM   6467 O O   . ILE D 4 99  ? 162.217 166.780 184.429 1.00 72.48  ? 81  ILE B O   1 
ATOM   6468 C CB  . ILE D 4 99  ? 163.000 165.266 186.845 1.00 53.40  ? 81  ILE B CB  1 
ATOM   6469 C CG1 . ILE D 4 99  ? 163.627 164.114 187.627 1.00 58.74  ? 81  ILE B CG1 1 
ATOM   6470 C CG2 . ILE D 4 99  ? 162.134 166.109 187.759 1.00 58.47  ? 81  ILE B CG2 1 
ATOM   6471 C CD1 . ILE D 4 99  ? 164.705 164.549 188.587 1.00 63.70  ? 81  ILE B CD1 1 
ATOM   6472 N N   . TRP D 4 100 ? 160.196 165.802 184.771 1.00 66.21  ? 82  TRP B N   1 
ATOM   6473 C CA  . TRP D 4 100 ? 159.398 166.768 184.029 1.00 63.94  ? 82  TRP B CA  1 
ATOM   6474 C C   . TRP D 4 100 ? 158.696 167.741 184.965 1.00 67.32  ? 82  TRP B C   1 
ATOM   6475 O O   . TRP D 4 100 ? 158.428 167.431 186.131 1.00 74.29  ? 82  TRP B O   1 
ATOM   6476 C CB  . TRP D 4 100 ? 158.298 166.110 183.183 1.00 67.70  ? 82  TRP B CB  1 
ATOM   6477 C CG  . TRP D 4 100 ? 158.618 164.862 182.436 1.00 68.35  ? 82  TRP B CG  1 
ATOM   6478 C CD1 . TRP D 4 100 ? 158.707 163.602 182.944 1.00 73.07  ? 82  TRP B CD1 1 
ATOM   6479 C CD2 . TRP D 4 100 ? 158.821 164.741 181.024 1.00 64.16  ? 82  TRP B CD2 1 
ATOM   6480 N NE1 . TRP D 4 100 ? 158.980 162.706 181.940 1.00 75.20  ? 82  TRP B NE1 1 
ATOM   6481 C CE2 . TRP D 4 100 ? 159.052 163.382 180.751 1.00 69.73  ? 82  TRP B CE2 1 
ATOM   6482 C CE3 . TRP D 4 100 ? 158.848 165.654 179.968 1.00 68.10  ? 82  TRP B CE3 1 
ATOM   6483 C CZ2 . TRP D 4 100 ? 159.314 162.915 179.468 1.00 69.91  ? 82  TRP B CZ2 1 
ATOM   6484 C CZ3 . TRP D 4 100 ? 159.101 165.188 178.696 1.00 71.01  ? 82  TRP B CZ3 1 
ATOM   6485 C CH2 . TRP D 4 100 ? 159.330 163.832 178.456 1.00 70.25  ? 82  TRP B CH2 1 
ATOM   6486 N N   . ASP D 4 101 ? 158.356 168.903 184.411 1.00 70.92  ? 83  ASP B N   1 
ATOM   6487 C CA  . ASP D 4 101 ? 157.409 169.835 185.008 1.00 73.33  ? 83  ASP B CA  1 
ATOM   6488 C C   . ASP D 4 101 ? 156.103 169.732 184.230 1.00 72.28  ? 83  ASP B C   1 
ATOM   6489 O O   . ASP D 4 101 ? 156.083 169.950 183.014 1.00 77.84  ? 83  ASP B O   1 
ATOM   6490 C CB  . ASP D 4 101 ? 157.952 171.262 184.975 1.00 77.83  ? 83  ASP B CB  1 
ATOM   6491 C CG  . ASP D 4 101 ? 156.929 172.288 185.416 1.00 82.50  ? 83  ASP B CG  1 
ATOM   6492 O OD1 . ASP D 4 101 ? 156.032 171.940 186.212 1.00 83.97  ? 83  ASP B OD1 1 
ATOM   6493 O OD2 . ASP D 4 101 ? 157.021 173.449 184.966 1.00 79.50  ? 83  ASP B OD2 1 
ATOM   6494 N N   . SER D 4 102 ? 155.017 169.402 184.929 1.00 66.52  ? 84  SER B N   1 
ATOM   6495 C CA  . SER D 4 102 ? 153.773 169.058 184.251 1.00 65.48  ? 84  SER B CA  1 
ATOM   6496 C C   . SER D 4 102 ? 153.052 170.270 183.677 1.00 74.05  ? 84  SER B C   1 
ATOM   6497 O O   . SER D 4 102 ? 152.454 170.171 182.600 1.00 81.58  ? 84  SER B O   1 
ATOM   6498 C CB  . SER D 4 102 ? 152.842 168.315 185.208 1.00 70.96  ? 84  SER B CB  1 
ATOM   6499 O OG  . SER D 4 102 ? 152.671 169.036 186.415 1.00 78.76  ? 84  SER B OG  1 
ATOM   6500 N N   . TYR D 4 103 ? 153.084 171.409 184.373 1.00 73.01  ? 85  TYR B N   1 
ATOM   6501 C CA  . TYR D 4 103 ? 152.264 172.546 183.963 1.00 71.30  ? 85  TYR B CA  1 
ATOM   6502 C C   . TYR D 4 103 ? 152.702 173.100 182.613 1.00 70.25  ? 85  TYR B C   1 
ATOM   6503 O O   . TYR D 4 103 ? 151.866 173.334 181.733 1.00 73.91  ? 85  TYR B O   1 
ATOM   6504 C CB  . TYR D 4 103 ? 152.316 173.644 185.024 1.00 69.20  ? 85  TYR B CB  1 
ATOM   6505 C CG  . TYR D 4 103 ? 151.491 173.368 186.260 1.00 68.02  ? 85  TYR B CG  1 
ATOM   6506 C CD1 . TYR D 4 103 ? 150.909 172.128 186.472 1.00 70.48  ? 85  TYR B CD1 1 
ATOM   6507 C CD2 . TYR D 4 103 ? 151.299 174.350 187.218 1.00 68.77  ? 85  TYR B CD2 1 
ATOM   6508 C CE1 . TYR D 4 103 ? 150.160 171.877 187.603 1.00 73.03  ? 85  TYR B CE1 1 
ATOM   6509 C CE2 . TYR D 4 103 ? 150.552 174.108 188.350 1.00 66.43  ? 85  TYR B CE2 1 
ATOM   6510 C CZ  . TYR D 4 103 ? 149.987 172.871 188.538 1.00 68.99  ? 85  TYR B CZ  1 
ATOM   6511 O OH  . TYR D 4 103 ? 149.240 172.627 189.666 1.00 70.25  ? 85  TYR B OH  1 
ATOM   6512 N N   . THR D 4 104 ? 154.001 173.313 182.429 1.00 72.62  ? 86  THR B N   1 
ATOM   6513 C CA  . THR D 4 104 ? 154.520 173.968 181.238 1.00 73.61  ? 86  THR B CA  1 
ATOM   6514 C C   . THR D 4 104 ? 155.319 173.040 180.333 1.00 74.20  ? 86  THR B C   1 
ATOM   6515 O O   . THR D 4 104 ? 155.953 173.520 179.387 1.00 81.23  ? 86  THR B O   1 
ATOM   6516 C CB  . THR D 4 104 ? 155.375 175.176 181.636 1.00 80.44  ? 86  THR B CB  1 
ATOM   6517 O OG1 . THR D 4 104 ? 156.726 174.757 181.852 1.00 82.25  ? 86  THR B OG1 1 
ATOM   6518 C CG2 . THR D 4 104 ? 154.838 175.818 182.907 1.00 82.25  ? 86  THR B CG2 1 
ATOM   6519 N N   . THR D 4 105 ? 155.345 171.739 180.627 1.00 72.46  ? 87  THR B N   1 
ATOM   6520 C CA  . THR D 4 105 ? 155.777 170.693 179.703 1.00 74.45  ? 87  THR B CA  1 
ATOM   6521 C C   . THR D 4 105 ? 157.294 170.682 179.500 1.00 72.98  ? 87  THR B C   1 
ATOM   6522 O O   . THR D 4 105 ? 157.850 169.701 178.993 1.00 75.83  ? 87  THR B O   1 
ATOM   6523 C CB  . THR D 4 105 ? 155.001 170.848 178.378 1.00 80.15  ? 87  THR B CB  1 
ATOM   6524 O OG1 . THR D 4 105 ? 153.709 170.243 178.514 1.00 81.08  ? 87  THR B OG1 1 
ATOM   6525 C CG2 . THR D 4 105 ? 155.709 170.220 177.181 1.00 80.29  ? 87  THR B CG2 1 
ATOM   6526 N N   . ASN D 4 106 ? 157.997 171.705 179.981 1.00 78.39  ? 88  ASN B N   1 
ATOM   6527 C CA  . ASN D 4 106 ? 159.452 171.666 179.913 1.00 79.66  ? 88  ASN B CA  1 
ATOM   6528 C C   . ASN D 4 106 ? 159.993 170.626 180.884 1.00 81.23  ? 88  ASN B C   1 
ATOM   6529 O O   . ASN D 4 106 ? 159.498 170.479 182.004 1.00 87.12  ? 88  ASN B O   1 
ATOM   6530 C CB  . ASN D 4 106 ? 160.061 173.035 180.218 1.00 78.41  ? 88  ASN B CB  1 
ATOM   6531 C CG  . ASN D 4 106 ? 159.764 173.507 181.617 1.00 84.95  ? 88  ASN B CG  1 
ATOM   6532 O OD1 . ASN D 4 106 ? 158.915 172.949 182.302 1.00 88.02  ? 88  ASN B OD1 1 
ATOM   6533 N ND2 . ASN D 4 106 ? 160.459 174.552 182.049 1.00 84.53  ? 88  ASN B ND2 1 
ATOM   6534 N N   . LYS D 4 107 ? 161.017 169.903 180.447 1.00 67.35  ? 89  LYS B N   1 
ATOM   6535 C CA  . LYS D 4 107 ? 161.621 168.846 181.243 1.00 66.10  ? 89  LYS B CA  1 
ATOM   6536 C C   . LYS D 4 107 ? 162.795 169.411 182.030 1.00 70.63  ? 89  LYS B C   1 
ATOM   6537 O O   . LYS D 4 107 ? 163.687 170.047 181.460 1.00 73.65  ? 89  LYS B O   1 
ATOM   6538 C CB  . LYS D 4 107 ? 162.056 167.682 180.351 1.00 69.68  ? 89  LYS B CB  1 
ATOM   6539 C CG  . LYS D 4 107 ? 162.956 168.069 179.194 1.00 76.35  ? 89  LYS B CG  1 
ATOM   6540 C CD  . LYS D 4 107 ? 163.665 166.856 178.624 1.00 75.78  ? 89  LYS B CD  1 
ATOM   6541 C CE  . LYS D 4 107 ? 162.706 165.957 177.865 1.00 75.83  ? 89  LYS B CE  1 
ATOM   6542 N NZ  . LYS D 4 107 ? 161.776 166.734 177.003 1.00 73.33  ? 89  LYS B NZ  1 
ATOM   6543 N N   . VAL D 4 108 ? 162.780 169.192 183.341 1.00 64.16  ? 90  VAL B N   1 
ATOM   6544 C CA  . VAL D 4 108 ? 163.749 169.822 184.232 1.00 58.91  ? 90  VAL B CA  1 
ATOM   6545 C C   . VAL D 4 108 ? 165.073 169.075 184.238 1.00 61.36  ? 90  VAL B C   1 
ATOM   6546 O O   . VAL D 4 108 ? 166.139 169.684 184.130 1.00 65.57  ? 90  VAL B O   1 
ATOM   6547 C CB  . VAL D 4 108 ? 163.164 169.933 185.655 1.00 63.12  ? 90  VAL B CB  1 
ATOM   6548 C CG1 . VAL D 4 108 ? 164.005 170.874 186.497 1.00 67.44  ? 90  VAL B CG1 1 
ATOM   6549 C CG2 . VAL D 4 108 ? 161.724 170.408 185.601 1.00 64.90  ? 90  VAL B CG2 1 
ATOM   6550 N N   . HIS D 4 109 ? 165.040 167.750 184.367 1.00 65.36  ? 91  HIS B N   1 
ATOM   6551 C CA  . HIS D 4 109 ? 166.271 166.999 184.578 1.00 60.44  ? 91  HIS B CA  1 
ATOM   6552 C C   . HIS D 4 109 ? 166.305 165.750 183.711 1.00 69.16  ? 91  HIS B C   1 
ATOM   6553 O O   . HIS D 4 109 ? 165.268 165.154 183.411 1.00 79.97  ? 91  HIS B O   1 
ATOM   6554 C CB  . HIS D 4 109 ? 166.432 166.592 186.047 1.00 62.35  ? 91  HIS B CB  1 
ATOM   6555 C CG  . HIS D 4 109 ? 167.160 167.598 186.881 1.00 65.11  ? 91  HIS B CG  1 
ATOM   6556 N ND1 . HIS D 4 109 ? 166.596 168.191 187.990 1.00 69.10  ? 91  HIS B ND1 1 
ATOM   6557 C CD2 . HIS D 4 109 ? 168.411 168.104 186.779 1.00 67.12  ? 91  HIS B CD2 1 
ATOM   6558 C CE1 . HIS D 4 109 ? 167.467 169.024 188.531 1.00 67.55  ? 91  HIS B CE1 1 
ATOM   6559 N NE2 . HIS D 4 109 ? 168.576 168.990 187.815 1.00 67.74  ? 91  HIS B NE2 1 
ATOM   6560 N N   . ALA D 4 110 ? 167.519 165.344 183.341 1.00 59.02  ? 92  ALA B N   1 
ATOM   6561 C CA  . ALA D 4 110 ? 167.757 164.085 182.639 1.00 55.47  ? 92  ALA B CA  1 
ATOM   6562 C C   . ALA D 4 110 ? 168.944 163.400 183.300 1.00 59.83  ? 92  ALA B C   1 
ATOM   6563 O O   . ALA D 4 110 ? 170.054 163.941 183.297 1.00 66.51  ? 92  ALA B O   1 
ATOM   6564 C CB  . ALA D 4 110 ? 168.017 164.312 181.151 1.00 58.92  ? 92  ALA B CB  1 
ATOM   6565 N N   . ILE D 4 111 ? 168.715 162.222 183.860 1.00 59.28  ? 93  ILE B N   1 
ATOM   6566 C CA  . ILE D 4 111 ? 169.727 161.481 184.609 1.00 55.18  ? 93  ILE B CA  1 
ATOM   6567 C C   . ILE D 4 111 ? 170.116 160.248 183.803 1.00 58.73  ? 93  ILE B C   1 
ATOM   6568 O O   . ILE D 4 111 ? 169.228 159.465 183.424 1.00 68.08  ? 93  ILE B O   1 
ATOM   6569 C CB  . ILE D 4 111 ? 169.214 161.077 186.002 1.00 60.81  ? 93  ILE B CB  1 
ATOM   6570 C CG1 . ILE D 4 111 ? 168.961 162.318 186.856 1.00 65.14  ? 93  ILE B CG1 1 
ATOM   6571 C CG2 . ILE D 4 111 ? 170.207 160.155 186.688 1.00 63.99  ? 93  ILE B CG2 1 
ATOM   6572 C CD1 . ILE D 4 111 ? 167.930 162.110 187.937 1.00 64.76  ? 93  ILE B CD1 1 
ATOM   6573 N N   . PRO D 4 112 ? 171.403 160.047 183.509 1.00 60.25  ? 94  PRO B N   1 
ATOM   6574 C CA  . PRO D 4 112 ? 171.830 158.821 182.830 1.00 61.95  ? 94  PRO B CA  1 
ATOM   6575 C C   . PRO D 4 112 ? 172.125 157.701 183.811 1.00 69.19  ? 94  PRO B C   1 
ATOM   6576 O O   . PRO D 4 112 ? 172.883 157.886 184.768 1.00 71.85  ? 94  PRO B O   1 
ATOM   6577 C CB  . PRO D 4 112 ? 173.089 159.261 182.076 1.00 60.74  ? 94  PRO B CB  1 
ATOM   6578 C CG  . PRO D 4 112 ? 173.617 160.433 182.851 1.00 65.55  ? 94  PRO B CG  1 
ATOM   6579 C CD  . PRO D 4 112 ? 172.524 160.971 183.743 1.00 64.39  ? 94  PRO B CD  1 
ATOM   6580 N N   . LEU D 4 113 ? 171.535 156.534 183.581 1.00 83.69  ? 95  LEU B N   1 
ATOM   6581 C CA  . LEU D 4 113 ? 171.676 155.398 184.476 1.00 87.02  ? 95  LEU B CA  1 
ATOM   6582 C C   . LEU D 4 113 ? 172.794 154.480 184.003 1.00 88.54  ? 95  LEU B C   1 
ATOM   6583 O O   . LEU D 4 113 ? 173.037 154.332 182.803 1.00 84.82  ? 95  LEU B O   1 
ATOM   6584 C CB  . LEU D 4 113 ? 170.365 154.617 184.567 1.00 79.56  ? 95  LEU B CB  1 
ATOM   6585 C CG  . LEU D 4 113 ? 169.141 155.432 184.976 1.00 72.48  ? 95  LEU B CG  1 
ATOM   6586 C CD1 . LEU D 4 113 ? 167.906 154.562 184.973 1.00 72.77  ? 95  LEU B CD1 1 
ATOM   6587 C CD2 . LEU D 4 113 ? 169.350 156.061 186.341 1.00 73.73  ? 95  LEU B CD2 1 
ATOM   6588 N N   . ARG D 4 114 ? 173.478 153.860 184.967 1.00 106.09 ? 96  ARG B N   1 
ATOM   6589 C CA  . ARG D 4 114 ? 174.554 152.935 184.628 1.00 107.46 ? 96  ARG B CA  1 
ATOM   6590 C C   . ARG D 4 114 ? 174.008 151.656 184.006 1.00 107.33 ? 96  ARG B C   1 
ATOM   6591 O O   . ARG D 4 114 ? 174.623 151.092 183.094 1.00 109.32 ? 96  ARG B O   1 
ATOM   6592 C CB  . ARG D 4 114 ? 175.389 152.622 185.870 1.00 104.89 ? 96  ARG B CB  1 
ATOM   6593 C CG  . ARG D 4 114 ? 175.873 153.856 186.615 1.00 106.72 ? 96  ARG B CG  1 
ATOM   6594 C CD  . ARG D 4 114 ? 176.583 153.484 187.910 1.00 108.64 ? 96  ARG B CD  1 
ATOM   6595 N NE  . ARG D 4 114 ? 177.286 154.619 188.496 1.00 109.96 ? 96  ARG B NE  1 
ATOM   6596 C CZ  . ARG D 4 114 ? 178.409 154.527 189.197 1.00 107.64 ? 96  ARG B CZ  1 
ATOM   6597 N NH1 . ARG D 4 114 ? 178.983 153.358 189.435 1.00 106.73 ? 96  ARG B NH1 1 
ATOM   6598 N NH2 . ARG D 4 114 ? 178.968 155.635 189.675 1.00 104.34 ? 96  ARG B NH2 1 
ATOM   6599 N N   . SER D 4 115 ? 172.861 151.184 184.484 1.00 96.18  ? 97  SER B N   1 
ATOM   6600 C CA  . SER D 4 115 ? 172.218 149.983 183.968 1.00 93.71  ? 97  SER B CA  1 
ATOM   6601 C C   . SER D 4 115 ? 170.934 150.372 183.251 1.00 91.32  ? 97  SER B C   1 
ATOM   6602 O O   . SER D 4 115 ? 170.082 151.060 183.824 1.00 92.93  ? 97  SER B O   1 
ATOM   6603 C CB  . SER D 4 115 ? 171.925 148.994 185.092 1.00 92.41  ? 97  SER B CB  1 
ATOM   6604 O OG  . SER D 4 115 ? 170.902 148.090 184.714 1.00 93.73  ? 97  SER B OG  1 
ATOM   6605 N N   . SER D 4 116 ? 170.795 149.927 182.002 1.00 82.44  ? 98  SER B N   1 
ATOM   6606 C CA  . SER D 4 116 ? 169.639 150.283 181.190 1.00 85.50  ? 98  SER B CA  1 
ATOM   6607 C C   . SER D 4 116 ? 168.367 149.562 181.611 1.00 83.85  ? 98  SER B C   1 
ATOM   6608 O O   . SER D 4 116 ? 167.284 149.944 181.155 1.00 85.13  ? 98  SER B O   1 
ATOM   6609 C CB  . SER D 4 116 ? 169.928 149.989 179.718 1.00 85.67  ? 98  SER B CB  1 
ATOM   6610 O OG  . SER D 4 116 ? 171.185 150.514 179.330 1.00 87.76  ? 98  SER B OG  1 
ATOM   6611 N N   . TRP D 4 117 ? 168.462 148.540 182.456 1.00 73.79  ? 99  TRP B N   1 
ATOM   6612 C CA  . TRP D 4 117 ? 167.310 147.740 182.856 1.00 75.13  ? 99  TRP B CA  1 
ATOM   6613 C C   . TRP D 4 117 ? 166.794 148.259 184.192 1.00 78.31  ? 99  TRP B C   1 
ATOM   6614 O O   . TRP D 4 117 ? 167.425 148.050 185.233 1.00 80.19  ? 99  TRP B O   1 
ATOM   6615 C CB  . TRP D 4 117 ? 167.685 146.264 182.947 1.00 77.41  ? 99  TRP B CB  1 
ATOM   6616 C CG  . TRP D 4 117 ? 168.514 145.794 181.797 1.00 75.04  ? 99  TRP B CG  1 
ATOM   6617 C CD1 . TRP D 4 117 ? 169.863 145.603 181.786 1.00 77.05  ? 99  TRP B CD1 1 
ATOM   6618 C CD2 . TRP D 4 117 ? 168.051 145.459 180.485 1.00 76.57  ? 99  TRP B CD2 1 
ATOM   6619 N NE1 . TRP D 4 117 ? 170.269 145.167 180.550 1.00 77.10  ? 99  TRP B NE1 1 
ATOM   6620 C CE2 . TRP D 4 117 ? 169.175 145.071 179.733 1.00 76.45  ? 99  TRP B CE2 1 
ATOM   6621 C CE3 . TRP D 4 117 ? 166.796 145.450 179.874 1.00 77.20  ? 99  TRP B CE3 1 
ATOM   6622 C CZ2 . TRP D 4 117 ? 169.081 144.679 178.404 1.00 76.98  ? 99  TRP B CZ2 1 
ATOM   6623 C CZ3 . TRP D 4 117 ? 166.705 145.059 178.555 1.00 77.36  ? 99  TRP B CZ3 1 
ATOM   6624 C CH2 . TRP D 4 117 ? 167.840 144.680 177.833 1.00 76.21  ? 99  TRP B CH2 1 
ATOM   6625 N N   . VAL D 4 118 ? 165.646 148.933 184.164 1.00 64.33  ? 100 VAL B N   1 
ATOM   6626 C CA  . VAL D 4 118 ? 165.047 149.498 185.364 1.00 59.88  ? 100 VAL B CA  1 
ATOM   6627 C C   . VAL D 4 118 ? 163.576 149.118 185.415 1.00 61.19  ? 100 VAL B C   1 
ATOM   6628 O O   . VAL D 4 118 ? 162.927 148.929 184.382 1.00 70.34  ? 100 VAL B O   1 
ATOM   6629 C CB  . VAL D 4 118 ? 165.214 151.029 185.424 1.00 59.75  ? 100 VAL B CB  1 
ATOM   6630 C CG1 . VAL D 4 118 ? 166.584 151.383 185.966 1.00 69.43  ? 100 VAL B CG1 1 
ATOM   6631 C CG2 . VAL D 4 118 ? 165.007 151.635 184.052 1.00 62.58  ? 100 VAL B CG2 1 
ATOM   6632 N N   . MET D 4 119 ? 163.052 149.003 186.634 1.00 74.80  ? 101 MET B N   1 
ATOM   6633 C CA  . MET D 4 119 ? 161.661 148.624 186.830 1.00 75.01  ? 101 MET B CA  1 
ATOM   6634 C C   . MET D 4 119 ? 160.961 149.382 187.950 1.00 77.95  ? 101 MET B C   1 
ATOM   6635 O O   . MET D 4 119 ? 159.810 149.055 188.255 1.00 79.10  ? 101 MET B O   1 
ATOM   6636 C CB  . MET D 4 119 ? 161.553 147.115 187.105 1.00 75.12  ? 101 MET B CB  1 
ATOM   6637 C CG  . MET D 4 119 ? 161.850 146.235 185.904 1.00 77.22  ? 101 MET B CG  1 
ATOM   6638 S SD  . MET D 4 119 ? 161.991 144.491 186.332 1.00 88.06  ? 101 MET B SD  1 
ATOM   6639 C CE  . MET D 4 119 ? 160.303 144.117 186.791 1.00 80.50  ? 101 MET B CE  1 
ATOM   6640 N N   . THR D 4 120 ? 161.598 150.371 188.573 1.00 76.20  ? 102 THR B N   1 
ATOM   6641 C CA  . THR D 4 120 ? 160.969 151.059 189.692 1.00 74.57  ? 102 THR B CA  1 
ATOM   6642 C C   . THR D 4 120 ? 161.524 152.471 189.820 1.00 73.86  ? 102 THR B C   1 
ATOM   6643 O O   . THR D 4 120 ? 162.650 152.754 189.405 1.00 71.57  ? 102 THR B O   1 
ATOM   6644 C CB  . THR D 4 120 ? 161.172 150.293 191.003 1.00 80.81  ? 102 THR B CB  1 
ATOM   6645 O OG1 . THR D 4 120 ? 160.388 150.898 192.039 1.00 87.74  ? 102 THR B OG1 1 
ATOM   6646 C CG2 . THR D 4 120 ? 162.639 150.298 191.408 1.00 74.89  ? 102 THR B CG2 1 
ATOM   6647 N N   . CYS D 4 121 ? 160.709 153.350 190.403 1.00 75.50  ? 103 CYS B N   1 
ATOM   6648 C CA  . CYS D 4 121 ? 161.096 154.727 190.678 1.00 73.20  ? 103 CYS B CA  1 
ATOM   6649 C C   . CYS D 4 121 ? 160.260 155.254 191.834 1.00 76.40  ? 103 CYS B C   1 
ATOM   6650 O O   . CYS D 4 121 ? 159.153 154.775 192.093 1.00 79.53  ? 103 CYS B O   1 
ATOM   6651 C CB  . CYS D 4 121 ? 160.922 155.622 189.449 1.00 72.07  ? 103 CYS B CB  1 
ATOM   6652 S SG  . CYS D 4 121 ? 162.399 155.775 188.443 1.00 86.06  ? 103 CYS B SG  1 
ATOM   6653 N N   . ALA D 4 122 ? 160.801 156.253 192.527 1.00 70.84  ? 104 ALA B N   1 
ATOM   6654 C CA  . ALA D 4 122 ? 160.104 156.858 193.653 1.00 71.03  ? 104 ALA B CA  1 
ATOM   6655 C C   . ALA D 4 122 ? 160.630 158.267 193.868 1.00 73.13  ? 104 ALA B C   1 
ATOM   6656 O O   . ALA D 4 122 ? 161.798 158.556 193.595 1.00 77.04  ? 104 ALA B O   1 
ATOM   6657 C CB  . ALA D 4 122 ? 160.273 156.028 194.930 1.00 70.23  ? 104 ALA B CB  1 
ATOM   6658 N N   . TYR D 4 123 ? 159.754 159.139 194.362 1.00 70.93  ? 105 TYR B N   1 
ATOM   6659 C CA  . TYR D 4 123 ? 160.097 160.523 194.657 1.00 70.62  ? 105 TYR B CA  1 
ATOM   6660 C C   . TYR D 4 123 ? 159.978 160.765 196.153 1.00 68.44  ? 105 TYR B C   1 
ATOM   6661 O O   . TYR D 4 123 ? 158.934 160.481 196.750 1.00 70.36  ? 105 TYR B O   1 
ATOM   6662 C CB  . TYR D 4 123 ? 159.192 161.493 193.896 1.00 66.38  ? 105 TYR B CB  1 
ATOM   6663 C CG  . TYR D 4 123 ? 159.904 162.733 193.413 1.00 73.20  ? 105 TYR B CG  1 
ATOM   6664 C CD1 . TYR D 4 123 ? 160.729 162.693 192.299 1.00 78.59  ? 105 TYR B CD1 1 
ATOM   6665 C CD2 . TYR D 4 123 ? 159.755 163.941 194.072 1.00 69.50  ? 105 TYR B CD2 1 
ATOM   6666 C CE1 . TYR D 4 123 ? 161.381 163.824 191.857 1.00 75.63  ? 105 TYR B CE1 1 
ATOM   6667 C CE2 . TYR D 4 123 ? 160.402 165.074 193.637 1.00 67.69  ? 105 TYR B CE2 1 
ATOM   6668 C CZ  . TYR D 4 123 ? 161.213 165.011 192.530 1.00 70.11  ? 105 TYR B CZ  1 
ATOM   6669 O OH  . TYR D 4 123 ? 161.861 166.141 192.092 1.00 72.14  ? 105 TYR B OH  1 
ATOM   6670 N N   . ALA D 4 124 ? 161.042 161.286 196.751 1.00 64.73  ? 106 ALA B N   1 
ATOM   6671 C CA  . ALA D 4 124 ? 161.027 161.560 198.178 1.00 64.49  ? 106 ALA B CA  1 
ATOM   6672 C C   . ALA D 4 124 ? 160.075 162.714 198.481 1.00 64.58  ? 106 ALA B C   1 
ATOM   6673 O O   . ALA D 4 124 ? 159.966 163.655 197.688 1.00 70.88  ? 106 ALA B O   1 
ATOM   6674 C CB  . ALA D 4 124 ? 162.430 161.896 198.675 1.00 66.09  ? 106 ALA B CB  1 
ATOM   6675 N N   . PRO D 4 125 ? 159.367 162.670 199.611 1.00 53.95  ? 107 PRO B N   1 
ATOM   6676 C CA  . PRO D 4 125 ? 158.476 163.786 199.959 1.00 57.05  ? 107 PRO B CA  1 
ATOM   6677 C C   . PRO D 4 125 ? 159.208 165.096 200.180 1.00 66.32  ? 107 PRO B C   1 
ATOM   6678 O O   . PRO D 4 125 ? 158.576 166.157 200.124 1.00 67.83  ? 107 PRO B O   1 
ATOM   6679 C CB  . PRO D 4 125 ? 157.784 163.304 201.242 1.00 55.14  ? 107 PRO B CB  1 
ATOM   6680 C CG  . PRO D 4 125 ? 158.629 162.195 201.754 1.00 55.88  ? 107 PRO B CG  1 
ATOM   6681 C CD  . PRO D 4 125 ? 159.261 161.556 200.565 1.00 56.39  ? 107 PRO B CD  1 
ATOM   6682 N N   . SER D 4 126 ? 160.515 165.062 200.438 1.00 71.35  ? 108 SER B N   1 
ATOM   6683 C CA  . SER D 4 126 ? 161.280 166.288 200.608 1.00 64.79  ? 108 SER B CA  1 
ATOM   6684 C C   . SER D 4 126 ? 161.689 166.917 199.285 1.00 63.44  ? 108 SER B C   1 
ATOM   6685 O O   . SER D 4 126 ? 162.201 168.041 199.287 1.00 68.17  ? 108 SER B O   1 
ATOM   6686 C CB  . SER D 4 126 ? 162.527 166.019 201.452 1.00 68.83  ? 108 SER B CB  1 
ATOM   6687 O OG  . SER D 4 126 ? 163.497 165.298 200.714 1.00 74.72  ? 108 SER B OG  1 
ATOM   6688 N N   . GLY D 4 127 ? 161.482 166.228 198.166 1.00 71.25  ? 109 GLY B N   1 
ATOM   6689 C CA  . GLY D 4 127 ? 161.848 166.773 196.877 1.00 76.11  ? 109 GLY B CA  1 
ATOM   6690 C C   . GLY D 4 127 ? 163.332 166.849 196.612 1.00 74.52  ? 109 GLY B C   1 
ATOM   6691 O O   . GLY D 4 127 ? 163.750 167.607 195.733 1.00 73.39  ? 109 GLY B O   1 
ATOM   6692 N N   . ASN D 4 128 ? 164.143 166.089 197.343 1.00 69.98  ? 110 ASN B N   1 
ATOM   6693 C CA  . ASN D 4 128 ? 165.591 166.151 197.205 1.00 71.97  ? 110 ASN B CA  1 
ATOM   6694 C C   . ASN D 4 128 ? 166.199 164.916 196.560 1.00 74.75  ? 110 ASN B C   1 
ATOM   6695 O O   . ASN D 4 128 ? 167.294 165.007 195.995 1.00 79.66  ? 110 ASN B O   1 
ATOM   6696 C CB  . ASN D 4 128 ? 166.242 166.358 198.576 1.00 72.74  ? 110 ASN B CB  1 
ATOM   6697 C CG  . ASN D 4 128 ? 166.058 167.762 199.103 1.00 73.64  ? 110 ASN B CG  1 
ATOM   6698 O OD1 . ASN D 4 128 ? 165.155 168.483 198.680 1.00 77.88  ? 110 ASN B OD1 1 
ATOM   6699 N ND2 . ASN D 4 128 ? 166.913 168.160 200.037 1.00 72.37  ? 110 ASN B ND2 1 
ATOM   6700 N N   . TYR D 4 129 ? 165.529 163.768 196.625 1.00 70.31  ? 111 TYR B N   1 
ATOM   6701 C CA  . TYR D 4 129 ? 166.136 162.500 196.250 1.00 70.64  ? 111 TYR B CA  1 
ATOM   6702 C C   . TYR D 4 129 ? 165.229 161.725 195.306 1.00 72.48  ? 111 TYR B C   1 
ATOM   6703 O O   . TYR D 4 129 ? 164.009 161.909 195.295 1.00 70.31  ? 111 TYR B O   1 
ATOM   6704 C CB  . TYR D 4 129 ? 166.432 161.642 197.484 1.00 69.87  ? 111 TYR B CB  1 
ATOM   6705 C CG  . TYR D 4 129 ? 167.439 162.245 198.434 1.00 69.18  ? 111 TYR B CG  1 
ATOM   6706 C CD1 . TYR D 4 129 ? 168.660 162.711 197.977 1.00 66.06  ? 111 TYR B CD1 1 
ATOM   6707 C CD2 . TYR D 4 129 ? 167.166 162.345 199.789 1.00 70.28  ? 111 TYR B CD2 1 
ATOM   6708 C CE1 . TYR D 4 129 ? 169.583 163.259 198.844 1.00 66.07  ? 111 TYR B CE1 1 
ATOM   6709 C CE2 . TYR D 4 129 ? 168.081 162.892 200.662 1.00 71.71  ? 111 TYR B CE2 1 
ATOM   6710 C CZ  . TYR D 4 129 ? 169.288 163.348 200.184 1.00 70.31  ? 111 TYR B CZ  1 
ATOM   6711 O OH  . TYR D 4 129 ? 170.206 163.895 201.049 1.00 73.51  ? 111 TYR B OH  1 
ATOM   6712 N N   . VAL D 4 130 ? 165.845 160.851 194.511 1.00 72.36  ? 112 VAL B N   1 
ATOM   6713 C CA  . VAL D 4 130 ? 165.125 159.937 193.629 1.00 60.15  ? 112 VAL B CA  1 
ATOM   6714 C C   . VAL D 4 130 ? 165.805 158.574 193.667 1.00 72.61  ? 112 VAL B C   1 
ATOM   6715 O O   . VAL D 4 130 ? 167.036 158.480 193.694 1.00 80.82  ? 112 VAL B O   1 
ATOM   6716 C CB  . VAL D 4 130 ? 165.048 160.471 192.186 1.00 64.48  ? 112 VAL B CB  1 
ATOM   6717 C CG1 . VAL D 4 130 ? 163.906 161.458 192.053 1.00 65.47  ? 112 VAL B CG1 1 
ATOM   6718 C CG2 . VAL D 4 130 ? 166.363 161.117 191.791 1.00 73.78  ? 112 VAL B CG2 1 
ATOM   6719 N N   . ALA D 4 131 ? 165.002 157.514 193.661 1.00 70.56  ? 113 ALA B N   1 
ATOM   6720 C CA  . ALA D 4 131 ? 165.502 156.150 193.748 1.00 68.88  ? 113 ALA B CA  1 
ATOM   6721 C C   . ALA D 4 131 ? 165.246 155.403 192.445 1.00 68.45  ? 113 ALA B C   1 
ATOM   6722 O O   . ALA D 4 131 ? 164.176 155.537 191.844 1.00 75.86  ? 113 ALA B O   1 
ATOM   6723 C CB  . ALA D 4 131 ? 164.847 155.402 194.911 1.00 69.26  ? 113 ALA B CB  1 
ATOM   6724 N N   . CYS D 4 132 ? 166.230 154.615 192.013 1.00 63.09  ? 114 CYS B N   1 
ATOM   6725 C CA  . CYS D 4 132 ? 166.097 153.790 190.820 1.00 63.85  ? 114 CYS B CA  1 
ATOM   6726 C C   . CYS D 4 132 ? 166.613 152.384 191.100 1.00 75.86  ? 114 CYS B C   1 
ATOM   6727 O O   . CYS D 4 132 ? 167.399 152.160 192.024 1.00 85.84  ? 114 CYS B O   1 
ATOM   6728 C CB  . CYS D 4 132 ? 166.849 154.388 189.627 1.00 69.24  ? 114 CYS B CB  1 
ATOM   6729 S SG  . CYS D 4 132 ? 168.645 154.346 189.783 1.00 75.05  ? 114 CYS B SG  1 
ATOM   6730 N N   . GLY D 4 133 ? 166.152 151.435 190.294 1.00 84.12  ? 115 GLY B N   1 
ATOM   6731 C CA  . GLY D 4 133 ? 166.582 150.053 190.438 1.00 86.68  ? 115 GLY B CA  1 
ATOM   6732 C C   . GLY D 4 133 ? 165.906 149.173 189.408 1.00 86.93  ? 115 GLY B C   1 
ATOM   6733 O O   . GLY D 4 133 ? 164.970 149.586 188.717 1.00 89.76  ? 115 GLY B O   1 
ATOM   6734 N N   . GLY D 4 134 ? 166.397 147.938 189.318 1.00 82.04  ? 116 GLY B N   1 
ATOM   6735 C CA  . GLY D 4 134 ? 165.849 146.983 188.373 1.00 82.00  ? 116 GLY B CA  1 
ATOM   6736 C C   . GLY D 4 134 ? 166.566 145.648 188.345 1.00 81.24  ? 116 GLY B C   1 
ATOM   6737 O O   . GLY D 4 134 ? 166.968 145.128 189.389 1.00 85.02  ? 116 GLY B O   1 
ATOM   6738 N N   . LEU D 4 135 ? 166.737 145.086 187.145 1.00 76.65  ? 117 LEU B N   1 
ATOM   6739 C CA  . LEU D 4 135 ? 167.443 143.816 186.997 1.00 74.55  ? 117 LEU B CA  1 
ATOM   6740 C C   . LEU D 4 135 ? 168.903 143.918 187.411 1.00 73.23  ? 117 LEU B C   1 
ATOM   6741 O O   . LEU D 4 135 ? 169.551 142.889 187.622 1.00 78.07  ? 117 LEU B O   1 
ATOM   6742 C CB  . LEU D 4 135 ? 167.341 143.321 185.552 1.00 72.24  ? 117 LEU B CB  1 
ATOM   6743 C CG  . LEU D 4 135 ? 166.386 142.171 185.230 1.00 74.45  ? 117 LEU B CG  1 
ATOM   6744 C CD1 . LEU D 4 135 ? 165.029 142.384 185.894 1.00 79.13  ? 117 LEU B CD1 1 
ATOM   6745 C CD2 . LEU D 4 135 ? 166.238 142.018 183.723 1.00 72.51  ? 117 LEU B CD2 1 
ATOM   6746 N N   . ASP D 4 136 ? 169.428 145.134 187.544 1.00 75.78  ? 118 ASP B N   1 
ATOM   6747 C CA  . ASP D 4 136 ? 170.802 145.358 187.973 1.00 78.21  ? 118 ASP B CA  1 
ATOM   6748 C C   . ASP D 4 136 ? 171.059 144.997 189.432 1.00 79.39  ? 118 ASP B C   1 
ATOM   6749 O O   . ASP D 4 136 ? 172.224 144.983 189.842 1.00 78.11  ? 118 ASP B O   1 
ATOM   6750 C CB  . ASP D 4 136 ? 171.179 146.810 187.668 1.00 84.14  ? 118 ASP B CB  1 
ATOM   6751 N N   . ASN D 4 137 ? 170.019 144.719 190.214 1.00 73.20  ? 119 ASN B N   1 
ATOM   6752 C CA  . ASN D 4 137 ? 170.068 144.105 191.542 1.00 66.23  ? 119 ASN B CA  1 
ATOM   6753 C C   . ASN D 4 137 ? 170.445 145.070 192.662 1.00 70.34  ? 119 ASN B C   1 
ATOM   6754 O O   . ASN D 4 137 ? 170.442 144.649 193.824 1.00 74.68  ? 119 ASN B O   1 
ATOM   6755 C CB  . ASN D 4 137 ? 171.044 142.919 191.598 1.00 69.52  ? 119 ASN B CB  1 
ATOM   6756 C CG  . ASN D 4 137 ? 170.358 141.613 191.915 1.00 75.59  ? 119 ASN B CG  1 
ATOM   6757 O OD1 . ASN D 4 137 ? 169.137 141.549 192.001 1.00 73.82  ? 119 ASN B OD1 1 
ATOM   6758 N ND2 . ASN D 4 137 ? 171.143 140.560 192.091 1.00 79.67  ? 119 ASN B ND2 1 
ATOM   6759 N N   . ILE D 4 138 ? 170.783 146.324 192.375 1.00 66.67  ? 120 ILE B N   1 
ATOM   6760 C CA  . ILE D 4 138 ? 171.144 147.270 193.424 1.00 67.03  ? 120 ILE B CA  1 
ATOM   6761 C C   . ILE D 4 138 ? 170.274 148.511 193.288 1.00 69.02  ? 120 ILE B C   1 
ATOM   6762 O O   . ILE D 4 138 ? 169.815 148.854 192.194 1.00 70.45  ? 120 ILE B O   1 
ATOM   6763 C CB  . ILE D 4 138 ? 172.644 147.642 193.395 1.00 66.22  ? 120 ILE B CB  1 
ATOM   6764 C CG1 . ILE D 4 138 ? 173.139 147.799 191.963 1.00 64.67  ? 120 ILE B CG1 1 
ATOM   6765 C CG2 . ILE D 4 138 ? 173.466 146.572 194.089 1.00 67.43  ? 120 ILE B CG2 1 
ATOM   6766 C CD1 . ILE D 4 138 ? 174.626 148.061 191.847 1.00 67.66  ? 120 ILE B CD1 1 
ATOM   6767 N N   . CYS D 4 139 ? 170.041 149.183 194.413 1.00 71.98  ? 121 CYS B N   1 
ATOM   6768 C CA  . CYS D 4 139 ? 169.165 150.349 194.456 1.00 68.60  ? 121 CYS B CA  1 
ATOM   6769 C C   . CYS D 4 139 ? 170.008 151.616 194.514 1.00 71.43  ? 121 CYS B C   1 
ATOM   6770 O O   . CYS D 4 139 ? 170.776 151.812 195.459 1.00 77.35  ? 121 CYS B O   1 
ATOM   6771 C CB  . CYS D 4 139 ? 168.221 150.280 195.654 1.00 64.08  ? 121 CYS B CB  1 
ATOM   6772 S SG  . CYS D 4 139 ? 166.877 151.462 195.584 1.00 72.85  ? 121 CYS B SG  1 
ATOM   6773 N N   . SER D 4 140 ? 169.861 152.474 193.512 1.00 72.81  ? 122 SER B N   1 
ATOM   6774 C CA  . SER D 4 140 ? 170.661 153.685 193.408 1.00 73.78  ? 122 SER B CA  1 
ATOM   6775 C C   . SER D 4 140 ? 169.855 154.873 193.907 1.00 81.13  ? 122 SER B C   1 
ATOM   6776 O O   . SER D 4 140 ? 168.709 155.074 193.487 1.00 84.27  ? 122 SER B O   1 
ATOM   6777 C CB  . SER D 4 140 ? 171.113 153.921 191.968 1.00 74.69  ? 122 SER B CB  1 
ATOM   6778 O OG  . SER D 4 140 ? 171.893 152.839 191.501 1.00 76.91  ? 122 SER B OG  1 
ATOM   6779 N N   . ILE D 4 141 ? 170.459 155.657 194.794 1.00 79.81  ? 123 ILE B N   1 
ATOM   6780 C CA  . ILE D 4 141 ? 169.844 156.844 195.371 1.00 75.35  ? 123 ILE B CA  1 
ATOM   6781 C C   . ILE D 4 141 ? 170.586 158.055 194.827 1.00 80.56  ? 123 ILE B C   1 
ATOM   6782 O O   . ILE D 4 141 ? 171.802 158.183 195.030 1.00 82.74  ? 123 ILE B O   1 
ATOM   6783 C CB  . ILE D 4 141 ? 169.895 156.816 196.905 1.00 71.35  ? 123 ILE B CB  1 
ATOM   6784 C CG1 . ILE D 4 141 ? 168.966 155.734 197.446 1.00 78.05  ? 123 ILE B CG1 1 
ATOM   6785 C CG2 . ILE D 4 141 ? 169.533 158.176 197.480 1.00 77.27  ? 123 ILE B CG2 1 
ATOM   6786 C CD1 . ILE D 4 141 ? 167.514 156.111 197.398 1.00 82.09  ? 123 ILE B CD1 1 
ATOM   6787 N N   . TYR D 4 142 ? 169.851 158.938 194.148 1.00 82.98  ? 124 TYR B N   1 
ATOM   6788 C CA  . TYR D 4 142 ? 170.379 160.133 193.508 1.00 81.62  ? 124 TYR B CA  1 
ATOM   6789 C C   . TYR D 4 142 ? 169.880 161.367 194.244 1.00 83.81  ? 124 TYR B C   1 
ATOM   6790 O O   . TYR D 4 142 ? 168.719 161.421 194.663 1.00 84.64  ? 124 TYR B O   1 
ATOM   6791 C CB  . TYR D 4 142 ? 169.928 160.222 192.047 1.00 78.66  ? 124 TYR B CB  1 
ATOM   6792 C CG  . TYR D 4 142 ? 170.437 159.136 191.132 1.00 80.04  ? 124 TYR B CG  1 
ATOM   6793 C CD1 . TYR D 4 142 ? 169.782 157.918 191.039 1.00 78.17  ? 124 TYR B CD1 1 
ATOM   6794 C CD2 . TYR D 4 142 ? 171.551 159.341 190.334 1.00 82.14  ? 124 TYR B CD2 1 
ATOM   6795 C CE1 . TYR D 4 142 ? 170.236 156.927 190.193 1.00 81.67  ? 124 TYR B CE1 1 
ATOM   6796 C CE2 . TYR D 4 142 ? 172.009 158.357 189.485 1.00 81.26  ? 124 TYR B CE2 1 
ATOM   6797 C CZ  . TYR D 4 142 ? 171.351 157.152 189.420 1.00 81.92  ? 124 TYR B CZ  1 
ATOM   6798 O OH  . TYR D 4 142 ? 171.806 156.167 188.576 1.00 83.66  ? 124 TYR B OH  1 
ATOM   6799 N N   . ASN D 4 143 ? 170.751 162.364 194.376 1.00 82.87  ? 125 ASN B N   1 
ATOM   6800 C CA  . ASN D 4 143 ? 170.399 163.647 194.968 1.00 82.15  ? 125 ASN B CA  1 
ATOM   6801 C C   . ASN D 4 143 ? 170.282 164.701 193.876 1.00 83.27  ? 125 ASN B C   1 
ATOM   6802 O O   . ASN D 4 143 ? 171.065 164.713 192.921 1.00 86.54  ? 125 ASN B O   1 
ATOM   6803 C CB  . ASN D 4 143 ? 171.424 164.079 196.021 1.00 76.14  ? 125 ASN B CB  1 
ATOM   6804 C CG  . ASN D 4 143 ? 172.738 164.518 195.418 1.00 75.95  ? 125 ASN B CG  1 
ATOM   6805 O OD1 . ASN D 4 143 ? 173.206 163.948 194.433 1.00 80.37  ? 125 ASN B OD1 1 
ATOM   6806 N ND2 . ASN D 4 143 ? 173.347 165.536 196.012 1.00 77.96  ? 125 ASN B ND2 1 
ATOM   6807 N N   . LEU D 4 144 ? 169.289 165.576 194.014 1.00 71.25  ? 126 LEU B N   1 
ATOM   6808 C CA  . LEU D 4 144 ? 168.980 166.559 192.985 1.00 63.46  ? 126 LEU B CA  1 
ATOM   6809 C C   . LEU D 4 144 ? 169.513 167.949 193.291 1.00 66.30  ? 126 LEU B C   1 
ATOM   6810 O O   . LEU D 4 144 ? 169.865 168.681 192.360 1.00 70.78  ? 126 LEU B O   1 
ATOM   6811 C CB  . LEU D 4 144 ? 167.466 166.640 192.776 1.00 62.45  ? 126 LEU B CB  1 
ATOM   6812 C CG  . LEU D 4 144 ? 166.774 165.334 192.397 1.00 63.53  ? 126 LEU B CG  1 
ATOM   6813 C CD1 . LEU D 4 144 ? 165.309 165.581 192.094 1.00 69.14  ? 126 LEU B CD1 1 
ATOM   6814 C CD2 . LEU D 4 144 ? 167.468 164.689 191.212 1.00 64.81  ? 126 LEU B CD2 1 
ATOM   6815 N N   . LYS D 4 145 ? 169.583 168.333 194.560 1.00 65.33  ? 127 LYS B N   1 
ATOM   6816 C CA  . LYS D 4 145 ? 169.986 169.680 194.954 1.00 64.68  ? 127 LYS B CA  1 
ATOM   6817 C C   . LYS D 4 145 ? 171.425 169.632 195.455 1.00 64.04  ? 127 LYS B C   1 
ATOM   6818 O O   . LYS D 4 145 ? 171.680 169.291 196.612 1.00 71.01  ? 127 LYS B O   1 
ATOM   6819 C CB  . LYS D 4 145 ? 169.039 170.231 196.014 1.00 65.13  ? 127 LYS B CB  1 
ATOM   6820 C CG  . LYS D 4 145 ? 167.633 170.486 195.504 1.00 65.87  ? 127 LYS B CG  1 
ATOM   6821 C CD  . LYS D 4 145 ? 166.667 170.746 196.643 1.00 66.04  ? 127 LYS B CD  1 
ATOM   6822 C CE  . LYS D 4 145 ? 165.240 170.846 196.137 1.00 67.20  ? 127 LYS B CE  1 
ATOM   6823 N NZ  . LYS D 4 145 ? 164.274 171.091 197.243 1.00 69.00  ? 127 LYS B NZ  1 
ATOM   6824 N N   . THR D 4 146 ? 172.365 169.977 194.579 1.00 68.39  ? 128 THR B N   1 
ATOM   6825 C CA  . THR D 4 146 ? 173.776 170.024 194.926 1.00 73.27  ? 128 THR B CA  1 
ATOM   6826 C C   . THR D 4 146 ? 174.402 171.287 194.352 1.00 73.54  ? 128 THR B C   1 
ATOM   6827 O O   . THR D 4 146 ? 173.878 171.897 193.416 1.00 76.25  ? 128 THR B O   1 
ATOM   6828 C CB  . THR D 4 146 ? 174.530 168.790 194.418 1.00 78.98  ? 128 THR B CB  1 
ATOM   6829 O OG1 . THR D 4 146 ? 175.939 168.986 194.590 1.00 80.14  ? 128 THR B OG1 1 
ATOM   6830 C CG2 . THR D 4 146 ? 174.238 168.563 192.953 1.00 77.67  ? 128 THR B CG2 1 
ATOM   6831 N N   . ARG D 4 147 ? 175.538 171.674 194.935 1.00 80.47  ? 129 ARG B N   1 
ATOM   6832 C CA  . ARG D 4 147 ? 176.191 172.918 194.542 1.00 82.37  ? 129 ARG B CA  1 
ATOM   6833 C C   . ARG D 4 147 ? 176.683 172.866 193.101 1.00 89.15  ? 129 ARG B C   1 
ATOM   6834 O O   . ARG D 4 147 ? 176.569 173.851 192.362 1.00 90.95  ? 129 ARG B O   1 
ATOM   6835 C CB  . ARG D 4 147 ? 177.350 173.220 195.490 1.00 77.49  ? 129 ARG B CB  1 
ATOM   6836 C CG  . ARG D 4 147 ? 176.916 173.591 196.894 1.00 83.85  ? 129 ARG B CG  1 
ATOM   6837 C CD  . ARG D 4 147 ? 176.521 175.054 196.982 1.00 89.84  ? 129 ARG B CD  1 
ATOM   6838 N NE  . ARG D 4 147 ? 177.651 175.902 197.343 1.00 93.60  ? 129 ARG B NE  1 
ATOM   6839 C CZ  . ARG D 4 147 ? 177.577 177.215 197.508 1.00 93.09  ? 129 ARG B CZ  1 
ATOM   6840 N NH1 . ARG D 4 147 ? 176.438 177.869 197.353 1.00 90.76  ? 129 ARG B NH1 1 
ATOM   6841 N NH2 . ARG D 4 147 ? 178.675 177.890 197.839 1.00 88.63  ? 129 ARG B NH2 1 
ATOM   6842 N N   . GLU D 4 148 ? 177.236 171.727 192.680 1.00 86.92  ? 130 GLU B N   1 
ATOM   6843 C CA  . GLU D 4 148 ? 177.836 171.623 191.355 1.00 83.21  ? 130 GLU B CA  1 
ATOM   6844 C C   . GLU D 4 148 ? 176.813 171.662 190.228 1.00 82.31  ? 130 GLU B C   1 
ATOM   6845 O O   . GLU D 4 148 ? 177.207 171.805 189.067 1.00 83.21  ? 130 GLU B O   1 
ATOM   6846 C CB  . GLU D 4 148 ? 178.664 170.343 191.257 1.00 80.40  ? 130 GLU B CB  1 
ATOM   6847 C CG  . GLU D 4 148 ? 180.049 170.453 191.868 1.00 84.62  ? 130 GLU B CG  1 
ATOM   6848 C CD  . GLU D 4 148 ? 180.064 170.149 193.352 1.00 88.63  ? 130 GLU B CD  1 
ATOM   6849 O OE1 . GLU D 4 148 ? 179.252 170.741 194.094 1.00 89.05  ? 130 GLU B OE1 1 
ATOM   6850 O OE2 . GLU D 4 148 ? 180.891 169.317 193.779 1.00 86.46  ? 130 GLU B OE2 1 
ATOM   6851 N N   . GLY D 4 149 ? 175.523 171.534 190.532 1.00 79.56  ? 131 GLY B N   1 
ATOM   6852 C CA  . GLY D 4 149 ? 174.479 171.698 189.546 1.00 81.85  ? 131 GLY B CA  1 
ATOM   6853 C C   . GLY D 4 149 ? 174.105 170.451 188.776 1.00 79.68  ? 131 GLY B C   1 
ATOM   6854 O O   . GLY D 4 149 ? 173.051 170.440 188.128 1.00 79.90  ? 131 GLY B O   1 
ATOM   6855 N N   . ASN D 4 150 ? 174.922 169.405 188.820 1.00 83.49  ? 132 ASN B N   1 
ATOM   6856 C CA  . ASN D 4 150 ? 174.607 168.159 188.141 1.00 82.39  ? 132 ASN B CA  1 
ATOM   6857 C C   . ASN D 4 150 ? 173.778 167.271 189.070 1.00 86.13  ? 132 ASN B C   1 
ATOM   6858 O O   . ASN D 4 150 ? 173.280 167.714 190.107 1.00 91.34  ? 132 ASN B O   1 
ATOM   6859 C CB  . ASN D 4 150 ? 175.888 167.470 187.679 1.00 83.06  ? 132 ASN B CB  1 
ATOM   6860 C CG  . ASN D 4 150 ? 176.963 167.469 188.744 1.00 89.58  ? 132 ASN B CG  1 
ATOM   6861 O OD1 . ASN D 4 150 ? 176.832 168.131 189.772 1.00 90.39  ? 132 ASN B OD1 1 
ATOM   6862 N ND2 . ASN D 4 150 ? 178.034 166.723 188.504 1.00 88.52  ? 132 ASN B ND2 1 
ATOM   6863 N N   . VAL D 4 151 ? 173.605 166.008 188.695 1.00 70.02  ? 133 VAL B N   1 
ATOM   6864 C CA  . VAL D 4 151 ? 172.949 165.013 189.534 1.00 67.40  ? 133 VAL B CA  1 
ATOM   6865 C C   . VAL D 4 151 ? 173.940 163.887 189.783 1.00 73.68  ? 133 VAL B C   1 
ATOM   6866 O O   . VAL D 4 151 ? 174.443 163.275 188.833 1.00 77.10  ? 133 VAL B O   1 
ATOM   6867 C CB  . VAL D 4 151 ? 171.658 164.481 188.886 1.00 67.65  ? 133 VAL B CB  1 
ATOM   6868 C CG1 . VAL D 4 151 ? 170.903 163.598 189.861 1.00 73.84  ? 133 VAL B CG1 1 
ATOM   6869 C CG2 . VAL D 4 151 ? 170.786 165.632 188.425 1.00 65.84  ? 133 VAL B CG2 1 
ATOM   6870 N N   . ARG D 4 152 ? 174.217 163.614 191.053 1.00 79.01  ? 134 ARG B N   1 
ATOM   6871 C CA  . ARG D 4 152 ? 175.241 162.660 191.449 1.00 77.98  ? 134 ARG B CA  1 
ATOM   6872 C C   . ARG D 4 152 ? 174.612 161.411 192.049 1.00 82.95  ? 134 ARG B C   1 
ATOM   6873 O O   . ARG D 4 152 ? 173.453 161.408 192.472 1.00 85.99  ? 134 ARG B O   1 
ATOM   6874 C CB  . ARG D 4 152 ? 176.204 163.283 192.463 1.00 80.39  ? 134 ARG B CB  1 
ATOM   6875 C CG  . ARG D 4 152 ? 177.210 164.246 191.869 1.00 82.43  ? 134 ARG B CG  1 
ATOM   6876 C CD  . ARG D 4 152 ? 178.307 164.662 192.858 1.00 85.44  ? 134 ARG B CD  1 
ATOM   6877 N NE  . ARG D 4 152 ? 177.818 165.412 194.011 1.00 88.65  ? 134 ARG B NE  1 
ATOM   6878 C CZ  . ARG D 4 152 ? 177.359 164.877 195.136 1.00 88.29  ? 134 ARG B CZ  1 
ATOM   6879 N NH1 . ARG D 4 152 ? 177.369 163.570 195.337 1.00 84.82  ? 134 ARG B NH1 1 
ATOM   6880 N NH2 . ARG D 4 152 ? 176.897 165.677 196.093 1.00 86.96  ? 134 ARG B NH2 1 
ATOM   6881 N N   . VAL D 4 153 ? 175.402 160.339 192.082 1.00 81.27  ? 135 VAL B N   1 
ATOM   6882 C CA  . VAL D 4 153 ? 174.988 159.085 192.708 1.00 80.08  ? 135 VAL B CA  1 
ATOM   6883 C C   . VAL D 4 153 ? 175.269 159.205 194.205 1.00 79.50  ? 135 VAL B C   1 
ATOM   6884 O O   . VAL D 4 153 ? 176.413 159.120 194.652 1.00 85.03  ? 135 VAL B O   1 
ATOM   6885 C CB  . VAL D 4 153 ? 175.683 157.873 192.080 1.00 81.44  ? 135 VAL B CB  1 
ATOM   6886 C CG1 . VAL D 4 153 ? 175.179 157.662 190.669 1.00 83.38  ? 135 VAL B CG1 1 
ATOM   6887 C CG2 . VAL D 4 153 ? 177.191 158.073 192.023 1.00 83.98  ? 135 VAL B CG2 1 
ATOM   6888 N N   . SER D 4 154 ? 174.216 159.434 194.989 1.00 77.63  ? 136 SER B N   1 
ATOM   6889 C CA  . SER D 4 154 ? 174.399 159.568 196.429 1.00 82.32  ? 136 SER B CA  1 
ATOM   6890 C C   . SER D 4 154 ? 174.766 158.233 197.062 1.00 87.01  ? 136 SER B C   1 
ATOM   6891 O O   . SER D 4 154 ? 175.722 158.146 197.841 1.00 84.08  ? 136 SER B O   1 
ATOM   6892 C CB  . SER D 4 154 ? 173.137 160.144 197.072 1.00 81.48  ? 136 SER B CB  1 
ATOM   6893 O OG  . SER D 4 154 ? 173.212 160.085 198.485 1.00 84.58  ? 136 SER B OG  1 
ATOM   6894 N N   . ARG D 4 155 ? 174.026 157.176 196.733 1.00 93.52  ? 137 ARG B N   1 
ATOM   6895 C CA  . ARG D 4 155 ? 174.260 155.889 197.377 1.00 86.52  ? 137 ARG B CA  1 
ATOM   6896 C C   . ARG D 4 155 ? 173.959 154.749 196.414 1.00 88.25  ? 137 ARG B C   1 
ATOM   6897 O O   . ARG D 4 155 ? 173.152 154.891 195.493 1.00 91.43  ? 137 ARG B O   1 
ATOM   6898 C CB  . ARG D 4 155 ? 173.412 155.734 198.643 1.00 84.11  ? 137 ARG B CB  1 
ATOM   6899 C CG  . ARG D 4 155 ? 174.157 155.142 199.826 1.00 86.54  ? 137 ARG B CG  1 
ATOM   6900 C CD  . ARG D 4 155 ? 175.323 156.017 200.242 1.00 87.92  ? 137 ARG B CD  1 
ATOM   6901 N NE  . ARG D 4 155 ? 175.880 155.610 201.527 1.00 92.33  ? 137 ARG B NE  1 
ATOM   6902 C CZ  . ARG D 4 155 ? 176.793 154.660 201.680 1.00 91.99  ? 137 ARG B CZ  1 
ATOM   6903 N NH1 . ARG D 4 155 ? 177.279 153.995 200.644 1.00 90.45  ? 137 ARG B NH1 1 
ATOM   6904 N NH2 . ARG D 4 155 ? 177.228 154.370 202.902 1.00 90.52  ? 137 ARG B NH2 1 
ATOM   6905 N N   . GLU D 4 156 ? 174.610 153.609 196.652 1.00 81.43  ? 138 GLU B N   1 
ATOM   6906 C CA  . GLU D 4 156 ? 174.406 152.383 195.878 1.00 81.99  ? 138 GLU B CA  1 
ATOM   6907 C C   . GLU D 4 156 ? 174.145 151.249 196.867 1.00 83.68  ? 138 GLU B C   1 
ATOM   6908 O O   . GLU D 4 156 ? 175.074 150.547 197.274 1.00 88.20  ? 138 GLU B O   1 
ATOM   6909 C CB  . GLU D 4 156 ? 175.612 152.090 194.991 1.00 84.20  ? 138 GLU B CB  1 
ATOM   6910 C CG  . GLU D 4 156 ? 175.849 153.118 193.899 1.00 90.39  ? 138 GLU B CG  1 
ATOM   6911 C CD  . GLU D 4 156 ? 176.882 152.664 192.886 1.00 91.41  ? 138 GLU B CD  1 
ATOM   6912 O OE1 . GLU D 4 156 ? 177.262 151.475 192.915 1.00 88.63  ? 138 GLU B OE1 1 
ATOM   6913 O OE2 . GLU D 4 156 ? 177.316 153.497 192.062 1.00 91.11  ? 138 GLU B OE2 1 
ATOM   6914 N N   . LEU D 4 157 ? 172.884 151.070 197.252 1.00 63.29  ? 139 LEU B N   1 
ATOM   6915 C CA  . LEU D 4 157 ? 172.530 150.042 198.220 1.00 59.05  ? 139 LEU B CA  1 
ATOM   6916 C C   . LEU D 4 157 ? 172.573 148.664 197.574 1.00 69.25  ? 139 LEU B C   1 
ATOM   6917 O O   . LEU D 4 157 ? 172.000 148.448 196.500 1.00 76.10  ? 139 LEU B O   1 
ATOM   6918 C CB  . LEU D 4 157 ? 171.143 150.315 198.795 1.00 58.27  ? 139 LEU B CB  1 
ATOM   6919 C CG  . LEU D 4 157 ? 170.905 151.717 199.355 1.00 62.62  ? 139 LEU B CG  1 
ATOM   6920 C CD1 . LEU D 4 157 ? 169.564 151.790 200.058 1.00 65.34  ? 139 LEU B CD1 1 
ATOM   6921 C CD2 . LEU D 4 157 ? 172.023 152.113 200.300 1.00 69.48  ? 139 LEU B CD2 1 
ATOM   6922 N N   . ALA D 4 158 ? 173.240 147.727 198.248 1.00 71.53  ? 140 ALA B N   1 
ATOM   6923 C CA  . ALA D 4 158 ? 173.449 146.378 197.749 1.00 63.26  ? 140 ALA B CA  1 
ATOM   6924 C C   . ALA D 4 158 ? 173.082 145.366 198.825 1.00 70.80  ? 140 ALA B C   1 
ATOM   6925 O O   . ALA D 4 158 ? 173.115 145.662 200.021 1.00 76.73  ? 140 ALA B O   1 
ATOM   6926 C CB  . ALA D 4 158 ? 174.905 146.161 197.317 1.00 61.25  ? 140 ALA B CB  1 
ATOM   6927 N N   . GLY D 4 159 ? 172.748 144.156 198.386 1.00 66.76  ? 141 GLY B N   1 
ATOM   6928 C CA  . GLY D 4 159 ? 172.463 143.087 199.323 1.00 67.63  ? 141 GLY B CA  1 
ATOM   6929 C C   . GLY D 4 159 ? 171.368 142.129 198.905 1.00 64.31  ? 141 GLY B C   1 
ATOM   6930 O O   . GLY D 4 159 ? 171.220 141.058 199.500 1.00 75.81  ? 141 GLY B O   1 
ATOM   6931 N N   . HIS D 4 160 ? 170.591 142.492 197.892 1.00 53.15  ? 142 HIS B N   1 
ATOM   6932 C CA  . HIS D 4 160 ? 169.549 141.598 197.418 1.00 62.73  ? 142 HIS B CA  1 
ATOM   6933 C C   . HIS D 4 160 ? 170.134 140.528 196.502 1.00 70.39  ? 142 HIS B C   1 
ATOM   6934 O O   . HIS D 4 160 ? 171.245 140.655 195.980 1.00 71.17  ? 142 HIS B O   1 
ATOM   6935 C CB  . HIS D 4 160 ? 168.459 142.374 196.682 1.00 66.11  ? 142 HIS B CB  1 
ATOM   6936 C CG  . HIS D 4 160 ? 167.376 142.890 197.575 1.00 63.79  ? 142 HIS B CG  1 
ATOM   6937 N ND1 . HIS D 4 160 ? 166.697 142.084 198.462 1.00 59.00  ? 142 HIS B ND1 1 
ATOM   6938 C CD2 . HIS D 4 160 ? 166.852 144.130 197.716 1.00 65.99  ? 142 HIS B CD2 1 
ATOM   6939 C CE1 . HIS D 4 160 ? 165.802 142.805 199.113 1.00 64.26  ? 142 HIS B CE1 1 
ATOM   6940 N NE2 . HIS D 4 160 ? 165.876 144.050 198.679 1.00 65.26  ? 142 HIS B NE2 1 
ATOM   6941 N N   . THR D 4 161 ? 169.363 139.459 196.312 1.00 70.38  ? 143 THR B N   1 
ATOM   6942 C CA  . THR D 4 161 ? 169.737 138.381 195.407 1.00 66.52  ? 143 THR B CA  1 
ATOM   6943 C C   . THR D 4 161 ? 168.906 138.339 194.136 1.00 65.64  ? 143 THR B C   1 
ATOM   6944 O O   . THR D 4 161 ? 169.334 137.729 193.155 1.00 68.73  ? 143 THR B O   1 
ATOM   6945 C CB  . THR D 4 161 ? 169.629 137.026 196.115 1.00 70.54  ? 143 THR B CB  1 
ATOM   6946 O OG1 . THR D 4 161 ? 168.342 136.908 196.732 1.00 73.52  ? 143 THR B OG1 1 
ATOM   6947 C CG2 . THR D 4 161 ? 170.705 136.895 197.177 1.00 69.70  ? 143 THR B CG2 1 
ATOM   6948 N N   . GLY D 4 162 ? 167.730 138.968 194.129 1.00 68.38  ? 144 GLY B N   1 
ATOM   6949 C CA  . GLY D 4 162 ? 166.887 139.030 192.959 1.00 66.92  ? 144 GLY B CA  1 
ATOM   6950 C C   . GLY D 4 162 ? 166.526 140.461 192.597 1.00 70.89  ? 144 GLY B C   1 
ATOM   6951 O O   . GLY D 4 162 ? 166.830 141.411 193.323 1.00 77.17  ? 144 GLY B O   1 
ATOM   6952 N N   . TYR D 4 163 ? 165.845 140.589 191.463 1.00 68.43  ? 145 TYR B N   1 
ATOM   6953 C CA  . TYR D 4 163 ? 165.551 141.900 190.905 1.00 69.60  ? 145 TYR B CA  1 
ATOM   6954 C C   . TYR D 4 163 ? 164.587 142.675 191.794 1.00 72.22  ? 145 TYR B C   1 
ATOM   6955 O O   . TYR D 4 163 ? 163.717 142.105 192.455 1.00 75.86  ? 145 TYR B O   1 
ATOM   6956 C CB  . TYR D 4 163 ? 164.960 141.757 189.504 1.00 65.76  ? 145 TYR B CB  1 
ATOM   6957 C CG  . TYR D 4 163 ? 163.569 141.170 189.481 1.00 63.98  ? 145 TYR B CG  1 
ATOM   6958 C CD1 . TYR D 4 163 ? 163.371 139.804 189.575 1.00 65.22  ? 145 TYR B CD1 1 
ATOM   6959 C CD2 . TYR D 4 163 ? 162.455 141.984 189.358 1.00 67.60  ? 145 TYR B CD2 1 
ATOM   6960 C CE1 . TYR D 4 163 ? 162.105 139.264 189.554 1.00 68.16  ? 145 TYR B CE1 1 
ATOM   6961 C CE2 . TYR D 4 163 ? 161.183 141.452 189.335 1.00 69.80  ? 145 TYR B CE2 1 
ATOM   6962 C CZ  . TYR D 4 163 ? 161.016 140.091 189.432 1.00 71.67  ? 145 TYR B CZ  1 
ATOM   6963 O OH  . TYR D 4 163 ? 159.750 139.556 189.410 1.00 75.57  ? 145 TYR B OH  1 
ATOM   6964 N N   . LEU D 4 164 ? 164.746 143.996 191.795 1.00 64.54  ? 146 LEU B N   1 
ATOM   6965 C CA  . LEU D 4 164 ? 163.895 144.884 192.574 1.00 58.92  ? 146 LEU B CA  1 
ATOM   6966 C C   . LEU D 4 164 ? 162.628 145.194 191.790 1.00 61.49  ? 146 LEU B C   1 
ATOM   6967 O O   . LEU D 4 164 ? 162.692 145.531 190.605 1.00 64.98  ? 146 LEU B O   1 
ATOM   6968 C CB  . LEU D 4 164 ? 164.629 146.180 192.914 1.00 59.39  ? 146 LEU B CB  1 
ATOM   6969 C CG  . LEU D 4 164 ? 165.546 146.202 194.136 1.00 64.04  ? 146 LEU B CG  1 
ATOM   6970 C CD1 . LEU D 4 164 ? 166.798 145.373 193.904 1.00 65.69  ? 146 LEU B CD1 1 
ATOM   6971 C CD2 . LEU D 4 164 ? 165.909 147.631 194.494 1.00 66.25  ? 146 LEU B CD2 1 
ATOM   6972 N N   . SER D 4 165 ? 161.479 145.079 192.452 1.00 66.15  ? 147 SER B N   1 
ATOM   6973 C CA  . SER D 4 165 ? 160.199 145.323 191.804 1.00 67.19  ? 147 SER B CA  1 
ATOM   6974 C C   . SER D 4 165 ? 159.566 146.649 192.194 1.00 66.70  ? 147 SER B C   1 
ATOM   6975 O O   . SER D 4 165 ? 158.819 147.221 191.394 1.00 74.50  ? 147 SER B O   1 
ATOM   6976 C CB  . SER D 4 165 ? 159.220 144.188 192.122 1.00 67.29  ? 147 SER B CB  1 
ATOM   6977 O OG  . SER D 4 165 ? 158.743 144.287 193.451 1.00 76.21  ? 147 SER B OG  1 
ATOM   6978 N N   . CYS D 4 166 ? 159.844 147.152 193.394 1.00 58.06  ? 148 CYS B N   1 
ATOM   6979 C CA  . CYS D 4 166 ? 159.281 148.419 193.835 1.00 60.16  ? 148 CYS B CA  1 
ATOM   6980 C C   . CYS D 4 166 ? 160.114 148.958 194.986 1.00 66.46  ? 148 CYS B C   1 
ATOM   6981 O O   . CYS D 4 166 ? 160.618 148.196 195.815 1.00 81.00  ? 148 CYS B O   1 
ATOM   6982 C CB  . CYS D 4 166 ? 157.819 148.265 194.263 1.00 55.85  ? 148 CYS B CB  1 
ATOM   6983 S SG  . CYS D 4 166 ? 156.836 149.768 194.102 1.00 74.01  ? 148 CYS B SG  1 
ATOM   6984 N N   . CYS D 4 167 ? 160.250 150.281 195.028 1.00 54.79  ? 149 CYS B N   1 
ATOM   6985 C CA  . CYS D 4 167 ? 160.959 150.945 196.110 1.00 52.51  ? 149 CYS B CA  1 
ATOM   6986 C C   . CYS D 4 167 ? 160.227 152.232 196.459 1.00 60.35  ? 149 CYS B C   1 
ATOM   6987 O O   . CYS D 4 167 ? 159.727 152.927 195.571 1.00 64.78  ? 149 CYS B O   1 
ATOM   6988 C CB  . CYS D 4 167 ? 162.416 151.236 195.733 1.00 49.90  ? 149 CYS B CB  1 
ATOM   6989 S SG  . CYS D 4 167 ? 162.646 152.490 194.464 1.00 65.30  ? 149 CYS B SG  1 
ATOM   6990 N N   . ARG D 4 168 ? 160.156 152.534 197.753 1.00 60.52  ? 150 ARG B N   1 
ATOM   6991 C CA  . ARG D 4 168 ? 159.470 153.722 198.240 1.00 52.44  ? 150 ARG B CA  1 
ATOM   6992 C C   . ARG D 4 168 ? 160.311 154.391 199.315 1.00 60.32  ? 150 ARG B C   1 
ATOM   6993 O O   . ARG D 4 168 ? 161.163 153.765 199.949 1.00 72.47  ? 150 ARG B O   1 
ATOM   6994 C CB  . ARG D 4 168 ? 158.081 153.390 198.794 1.00 49.25  ? 150 ARG B CB  1 
ATOM   6995 C CG  . ARG D 4 168 ? 157.096 152.917 197.749 1.00 51.51  ? 150 ARG B CG  1 
ATOM   6996 C CD  . ARG D 4 168 ? 156.900 153.969 196.681 1.00 57.84  ? 150 ARG B CD  1 
ATOM   6997 N NE  . ARG D 4 168 ? 155.596 153.865 196.042 1.00 64.81  ? 150 ARG B NE  1 
ATOM   6998 C CZ  . ARG D 4 168 ? 155.410 153.813 194.731 1.00 68.50  ? 150 ARG B CZ  1 
ATOM   6999 N NH1 . ARG D 4 168 ? 156.429 153.849 193.888 1.00 70.39  ? 150 ARG B NH1 1 
ATOM   7000 N NH2 . ARG D 4 168 ? 154.173 153.722 194.254 1.00 64.78  ? 150 ARG B NH2 1 
ATOM   7001 N N   . PHE D 4 169 ? 160.058 155.681 199.513 1.00 58.96  ? 151 PHE B N   1 
ATOM   7002 C CA  . PHE D 4 169 ? 160.756 156.486 200.506 1.00 57.22  ? 151 PHE B CA  1 
ATOM   7003 C C   . PHE D 4 169 ? 159.888 156.609 201.752 1.00 63.73  ? 151 PHE B C   1 
ATOM   7004 O O   . PHE D 4 169 ? 158.732 157.036 201.666 1.00 70.15  ? 151 PHE B O   1 
ATOM   7005 C CB  . PHE D 4 169 ? 161.073 157.874 199.955 1.00 59.04  ? 151 PHE B CB  1 
ATOM   7006 C CG  . PHE D 4 169 ? 162.449 158.009 199.380 1.00 55.13  ? 151 PHE B CG  1 
ATOM   7007 C CD1 . PHE D 4 169 ? 163.520 158.332 200.189 1.00 62.24  ? 151 PHE B CD1 1 
ATOM   7008 C CD2 . PHE D 4 169 ? 162.667 157.844 198.028 1.00 56.05  ? 151 PHE B CD2 1 
ATOM   7009 C CE1 . PHE D 4 169 ? 164.785 158.469 199.660 1.00 67.62  ? 151 PHE B CE1 1 
ATOM   7010 C CE2 . PHE D 4 169 ? 163.927 157.981 197.497 1.00 57.46  ? 151 PHE B CE2 1 
ATOM   7011 C CZ  . PHE D 4 169 ? 164.985 158.295 198.314 1.00 61.39  ? 151 PHE B CZ  1 
ATOM   7012 N N   . LEU D 4 170 ? 160.444 156.238 202.904 1.00 66.74  ? 152 LEU B N   1 
ATOM   7013 C CA  . LEU D 4 170 ? 159.786 156.533 204.171 1.00 64.02  ? 152 LEU B CA  1 
ATOM   7014 C C   . LEU D 4 170 ? 160.068 157.967 204.596 1.00 68.80  ? 152 LEU B C   1 
ATOM   7015 O O   . LEU D 4 170 ? 159.150 158.713 204.954 1.00 76.42  ? 152 LEU B O   1 
ATOM   7016 C CB  . LEU D 4 170 ? 160.252 155.553 205.248 1.00 66.52  ? 152 LEU B CB  1 
ATOM   7017 C CG  . LEU D 4 170 ? 159.364 154.347 205.549 1.00 67.56  ? 152 LEU B CG  1 
ATOM   7018 C CD1 . LEU D 4 170 ? 159.996 153.489 206.629 1.00 66.80  ? 152 LEU B CD1 1 
ATOM   7019 C CD2 . LEU D 4 170 ? 157.987 154.795 205.973 1.00 65.57  ? 152 LEU B CD2 1 
ATOM   7020 N N   . ASP D 4 171 ? 161.335 158.360 204.558 1.00 75.27  ? 153 ASP B N   1 
ATOM   7021 C CA  . ASP D 4 171 ? 161.774 159.727 204.801 1.00 72.65  ? 153 ASP B CA  1 
ATOM   7022 C C   . ASP D 4 171 ? 163.117 159.895 204.094 1.00 75.16  ? 153 ASP B C   1 
ATOM   7023 O O   . ASP D 4 171 ? 163.495 159.061 203.263 1.00 83.02  ? 153 ASP B O   1 
ATOM   7024 C CB  . ASP D 4 171 ? 161.765 160.027 206.315 1.00 73.24  ? 153 ASP B CB  1 
ATOM   7025 C CG  . ASP D 4 171 ? 162.770 159.198 207.119 1.00 83.85  ? 153 ASP B CG  1 
ATOM   7026 O OD1 . ASP D 4 171 ? 163.623 158.489 206.550 1.00 91.81  ? 153 ASP B OD1 1 
ATOM   7027 O OD2 . ASP D 4 171 ? 162.698 159.265 208.364 1.00 83.64  ? 153 ASP B OD2 1 
ATOM   7028 N N   . ASP D 4 172 ? 163.841 160.963 204.419 1.00 72.86  ? 154 ASP B N   1 
ATOM   7029 C CA  . ASP D 4 172 ? 165.119 161.205 203.759 1.00 79.08  ? 154 ASP B CA  1 
ATOM   7030 C C   . ASP D 4 172 ? 166.221 160.253 204.210 1.00 80.62  ? 154 ASP B C   1 
ATOM   7031 O O   . ASP D 4 172 ? 167.352 160.380 203.729 1.00 76.58  ? 154 ASP B O   1 
ATOM   7032 C CB  . ASP D 4 172 ? 165.559 162.651 203.989 1.00 83.50  ? 154 ASP B CB  1 
ATOM   7033 C CG  . ASP D 4 172 ? 164.658 163.649 203.293 1.00 89.56  ? 154 ASP B CG  1 
ATOM   7034 O OD1 . ASP D 4 172 ? 163.601 163.233 202.775 1.00 90.24  ? 154 ASP B OD1 1 
ATOM   7035 O OD2 . ASP D 4 172 ? 165.007 164.847 203.262 1.00 88.75  ? 154 ASP B OD2 1 
ATOM   7036 N N   . ASN D 4 173 ? 165.931 159.313 205.110 1.00 81.78  ? 155 ASN B N   1 
ATOM   7037 C CA  . ASN D 4 173 ? 166.928 158.368 205.592 1.00 71.19  ? 155 ASN B CA  1 
ATOM   7038 C C   . ASN D 4 173 ? 166.467 156.918 205.589 1.00 74.22  ? 155 ASN B C   1 
ATOM   7039 O O   . ASN D 4 173 ? 167.311 156.028 205.735 1.00 83.47  ? 155 ASN B O   1 
ATOM   7040 C CB  . ASN D 4 173 ? 167.369 158.739 207.015 1.00 74.64  ? 155 ASN B CB  1 
ATOM   7041 C CG  . ASN D 4 173 ? 168.763 158.254 207.335 1.00 83.36  ? 155 ASN B CG  1 
ATOM   7042 O OD1 . ASN D 4 173 ? 169.432 157.658 206.493 1.00 85.54  ? 155 ASN B OD1 1 
ATOM   7043 N ND2 . ASN D 4 173 ? 169.210 158.505 208.560 1.00 86.09  ? 155 ASN B ND2 1 
ATOM   7044 N N   . GLN D 4 174 ? 165.176 156.648 205.427 1.00 65.59  ? 156 GLN B N   1 
ATOM   7045 C CA  . GLN D 4 174 ? 164.646 155.292 205.443 1.00 66.85  ? 156 GLN B CA  1 
ATOM   7046 C C   . GLN D 4 174 ? 164.025 154.974 204.092 1.00 69.24  ? 156 GLN B C   1 
ATOM   7047 O O   . GLN D 4 174 ? 163.201 155.743 203.587 1.00 72.86  ? 156 GLN B O   1 
ATOM   7048 C CB  . GLN D 4 174 ? 163.608 155.119 206.553 1.00 66.28  ? 156 GLN B CB  1 
ATOM   7049 C CG  . GLN D 4 174 ? 164.191 154.747 207.902 1.00 67.54  ? 156 GLN B CG  1 
ATOM   7050 C CD  . GLN D 4 174 ? 163.148 154.739 209.001 1.00 69.86  ? 156 GLN B CD  1 
ATOM   7051 O OE1 . GLN D 4 174 ? 162.844 153.696 209.576 1.00 68.37  ? 156 GLN B OE1 1 
ATOM   7052 N NE2 . GLN D 4 174 ? 162.596 155.908 209.299 1.00 67.22  ? 156 GLN B NE2 1 
ATOM   7053 N N   . ILE D 4 175 ? 164.419 153.844 203.511 1.00 59.78  ? 157 ILE B N   1 
ATOM   7054 C CA  . ILE D 4 175 ? 163.910 153.402 202.219 1.00 47.83  ? 157 ILE B CA  1 
ATOM   7055 C C   . ILE D 4 175 ? 163.553 151.924 202.315 1.00 52.43  ? 157 ILE B C   1 
ATOM   7056 O O   . ILE D 4 175 ? 164.282 151.131 202.924 1.00 67.69  ? 157 ILE B O   1 
ATOM   7057 C CB  . ILE D 4 175 ? 164.929 153.672 201.090 1.00 48.54  ? 157 ILE B CB  1 
ATOM   7058 C CG1 . ILE D 4 175 ? 164.420 153.132 199.757 1.00 48.98  ? 157 ILE B CG1 1 
ATOM   7059 C CG2 . ILE D 4 175 ? 166.285 153.089 201.430 1.00 62.03  ? 157 ILE B CG2 1 
ATOM   7060 C CD1 . ILE D 4 175 ? 165.269 153.539 198.583 1.00 53.77  ? 157 ILE B CD1 1 
ATOM   7061 N N   . VAL D 4 176 ? 162.417 151.558 201.723 1.00 42.78  ? 158 VAL B N   1 
ATOM   7062 C CA  . VAL D 4 176 ? 161.880 150.204 201.779 1.00 43.07  ? 158 VAL B CA  1 
ATOM   7063 C C   . VAL D 4 176 ? 161.857 149.636 200.367 1.00 54.94  ? 158 VAL B C   1 
ATOM   7064 O O   . VAL D 4 176 ? 161.327 150.270 199.447 1.00 62.48  ? 158 VAL B O   1 
ATOM   7065 C CB  . VAL D 4 176 ? 160.474 150.179 202.402 1.00 43.18  ? 158 VAL B CB  1 
ATOM   7066 C CG1 . VAL D 4 176 ? 159.980 148.758 202.525 1.00 49.07  ? 158 VAL B CG1 1 
ATOM   7067 C CG2 . VAL D 4 176 ? 160.486 150.857 203.758 1.00 53.38  ? 158 VAL B CG2 1 
ATOM   7068 N N   . THR D 4 177 ? 162.426 148.444 200.198 1.00 61.81  ? 159 THR B N   1 
ATOM   7069 C CA  . THR D 4 177 ? 162.583 147.823 198.890 1.00 53.62  ? 159 THR B CA  1 
ATOM   7070 C C   . THR D 4 177 ? 162.034 146.405 198.901 1.00 58.41  ? 159 THR B C   1 
ATOM   7071 O O   . THR D 4 177 ? 162.148 145.689 199.901 1.00 67.90  ? 159 THR B O   1 
ATOM   7072 C CB  . THR D 4 177 ? 164.050 147.792 198.459 1.00 57.38  ? 159 THR B CB  1 
ATOM   7073 O OG1 . THR D 4 177 ? 164.857 147.324 199.545 1.00 68.94  ? 159 THR B OG1 1 
ATOM   7074 C CG2 . THR D 4 177 ? 164.513 149.179 198.056 1.00 58.86  ? 159 THR B CG2 1 
ATOM   7075 N N   . SER D 4 178 ? 161.438 146.008 197.779 1.00 56.06  ? 160 SER B N   1 
ATOM   7076 C CA  . SER D 4 178 ? 160.921 144.662 197.573 1.00 61.28  ? 160 SER B CA  1 
ATOM   7077 C C   . SER D 4 178 ? 161.623 144.051 196.371 1.00 65.54  ? 160 SER B C   1 
ATOM   7078 O O   . SER D 4 178 ? 161.725 144.689 195.318 1.00 68.91  ? 160 SER B O   1 
ATOM   7079 C CB  . SER D 4 178 ? 159.408 144.678 197.358 1.00 63.34  ? 160 SER B CB  1 
ATOM   7080 O OG  . SER D 4 178 ? 159.090 145.038 196.027 1.00 69.26  ? 160 SER B OG  1 
ATOM   7081 N N   . SER D 4 179 ? 162.103 142.821 196.524 1.00 75.44  ? 161 SER B N   1 
ATOM   7082 C CA  . SER D 4 179 ? 162.982 142.206 195.543 1.00 76.80  ? 161 SER B CA  1 
ATOM   7083 C C   . SER D 4 179 ? 162.352 140.953 194.950 1.00 73.68  ? 161 SER B C   1 
ATOM   7084 O O   . SER D 4 179 ? 161.287 140.496 195.373 1.00 73.30  ? 161 SER B O   1 
ATOM   7085 C CB  . SER D 4 179 ? 164.340 141.861 196.164 1.00 78.37  ? 161 SER B CB  1 
ATOM   7086 O OG  . SER D 4 179 ? 164.927 140.748 195.513 1.00 77.16  ? 161 SER B OG  1 
ATOM   7087 N N   . GLY D 4 180 ? 163.037 140.404 193.945 1.00 76.22  ? 162 GLY B N   1 
ATOM   7088 C CA  . GLY D 4 180 ? 162.565 139.182 193.317 1.00 75.25  ? 162 GLY B CA  1 
ATOM   7089 C C   . GLY D 4 180 ? 162.574 138.000 194.264 1.00 79.15  ? 162 GLY B C   1 
ATOM   7090 O O   . GLY D 4 180 ? 161.636 137.201 194.285 1.00 81.52  ? 162 GLY B O   1 
ATOM   7091 N N   . ASP D 4 181 ? 163.636 137.864 195.052 1.00 74.06  ? 163 ASP B N   1 
ATOM   7092 C CA  . ASP D 4 181 ? 163.633 136.875 196.115 1.00 67.43  ? 163 ASP B CA  1 
ATOM   7093 C C   . ASP D 4 181 ? 162.604 137.257 197.173 1.00 70.59  ? 163 ASP B C   1 
ATOM   7094 O O   . ASP D 4 181 ? 162.277 138.430 197.368 1.00 82.70  ? 163 ASP B O   1 
ATOM   7095 C CB  . ASP D 4 181 ? 165.022 136.747 196.735 1.00 67.70  ? 163 ASP B CB  1 
ATOM   7096 C CG  . ASP D 4 181 ? 165.604 138.082 197.134 1.00 76.49  ? 163 ASP B CG  1 
ATOM   7097 O OD1 . ASP D 4 181 ? 165.952 138.871 196.232 1.00 76.13  ? 163 ASP B OD1 1 
ATOM   7098 O OD2 . ASP D 4 181 ? 165.722 138.343 198.348 1.00 82.24  ? 163 ASP B OD2 1 
ATOM   7099 N N   . THR D 4 182 ? 162.090 136.243 197.866 1.00 58.49  ? 164 THR B N   1 
ATOM   7100 C CA  . THR D 4 182 ? 160.953 136.422 198.766 1.00 65.03  ? 164 THR B CA  1 
ATOM   7101 C C   . THR D 4 182 ? 161.374 137.168 200.036 1.00 70.49  ? 164 THR B C   1 
ATOM   7102 O O   . THR D 4 182 ? 161.395 136.625 201.140 1.00 81.63  ? 164 THR B O   1 
ATOM   7103 C CB  . THR D 4 182 ? 160.344 135.068 199.098 1.00 75.38  ? 164 THR B CB  1 
ATOM   7104 O OG1 . THR D 4 182 ? 161.069 134.473 200.182 1.00 87.25  ? 164 THR B OG1 1 
ATOM   7105 C CG2 . THR D 4 182 ? 160.433 134.148 197.894 1.00 70.91  ? 164 THR B CG2 1 
ATOM   7106 N N   . THR D 4 183 ? 161.700 138.448 199.860 1.00 59.07  ? 165 THR B N   1 
ATOM   7107 C CA  . THR D 4 183 ? 162.205 139.272 200.950 1.00 60.08  ? 165 THR B CA  1 
ATOM   7108 C C   . THR D 4 183 ? 161.765 140.714 200.756 1.00 66.06  ? 165 THR B C   1 
ATOM   7109 O O   . THR D 4 183 ? 161.412 141.136 199.652 1.00 69.65  ? 165 THR B O   1 
ATOM   7110 C CB  . THR D 4 183 ? 163.736 139.224 201.044 1.00 65.40  ? 165 THR B CB  1 
ATOM   7111 O OG1 . THR D 4 183 ? 164.299 140.211 200.173 1.00 70.25  ? 165 THR B OG1 1 
ATOM   7112 C CG2 . THR D 4 183 ? 164.269 137.850 200.668 1.00 66.63  ? 165 THR B CG2 1 
ATOM   7113 N N   . CYS D 4 184 ? 161.788 141.466 201.854 1.00 67.52  ? 166 CYS B N   1 
ATOM   7114 C CA  . CYS D 4 184 ? 161.647 142.914 201.823 1.00 67.56  ? 166 CYS B CA  1 
ATOM   7115 C C   . CYS D 4 184 ? 162.679 143.506 202.769 1.00 71.05  ? 166 CYS B C   1 
ATOM   7116 O O   . CYS D 4 184 ? 163.085 142.864 203.738 1.00 71.11  ? 166 CYS B O   1 
ATOM   7117 C CB  . CYS D 4 184 ? 160.240 143.367 202.221 1.00 64.89  ? 166 CYS B CB  1 
ATOM   7118 S SG  . CYS D 4 184 ? 158.988 143.112 200.953 1.00 67.85  ? 166 CYS B SG  1 
ATOM   7119 N N   . ALA D 4 185 ? 163.114 144.726 202.481 1.00 63.12  ? 167 ALA B N   1 
ATOM   7120 C CA  . ALA D 4 185 ? 164.196 145.314 203.255 1.00 58.05  ? 167 ALA B CA  1 
ATOM   7121 C C   . ALA D 4 185 ? 163.894 146.763 203.590 1.00 62.98  ? 167 ALA B C   1 
ATOM   7122 O O   . ALA D 4 185 ? 163.354 147.502 202.764 1.00 70.85  ? 167 ALA B O   1 
ATOM   7123 C CB  . ALA D 4 185 ? 165.526 145.225 202.503 1.00 58.06  ? 167 ALA B CB  1 
ATOM   7124 N N   . LEU D 4 186 ? 164.246 147.161 204.809 1.00 59.95  ? 168 LEU B N   1 
ATOM   7125 C CA  . LEU D 4 186 ? 164.271 148.559 205.212 1.00 60.72  ? 168 LEU B CA  1 
ATOM   7126 C C   . LEU D 4 186 ? 165.723 148.917 205.489 1.00 57.55  ? 168 LEU B C   1 
ATOM   7127 O O   . LEU D 4 186 ? 166.375 148.268 206.322 1.00 66.63  ? 168 LEU B O   1 
ATOM   7128 C CB  . LEU D 4 186 ? 163.380 148.800 206.432 1.00 56.67  ? 168 LEU B CB  1 
ATOM   7129 C CG  . LEU D 4 186 ? 163.399 150.123 207.209 1.00 57.18  ? 168 LEU B CG  1 
ATOM   7130 C CD1 . LEU D 4 186 ? 162.157 150.202 208.047 1.00 56.08  ? 168 LEU B CD1 1 
ATOM   7131 C CD2 . LEU D 4 186 ? 164.602 150.286 208.123 1.00 60.88  ? 168 LEU B CD2 1 
ATOM   7132 N N   . TRP D 4 187 ? 166.214 149.950 204.801 1.00 46.80  ? 169 TRP B N   1 
ATOM   7133 C CA  . TRP D 4 187 ? 167.632 150.258 204.695 1.00 46.10  ? 169 TRP B CA  1 
ATOM   7134 C C   . TRP D 4 187 ? 168.005 151.471 205.541 1.00 48.72  ? 169 TRP B C   1 
ATOM   7135 O O   . TRP D 4 187 ? 167.181 152.062 206.243 1.00 53.48  ? 169 TRP B O   1 
ATOM   7136 C CB  . TRP D 4 187 ? 168.016 150.516 203.238 1.00 48.90  ? 169 TRP B CB  1 
ATOM   7137 C CG  . TRP D 4 187 ? 167.796 149.367 202.322 1.00 56.50  ? 169 TRP B CG  1 
ATOM   7138 C CD1 . TRP D 4 187 ? 166.613 148.969 201.779 1.00 59.40  ? 169 TRP B CD1 1 
ATOM   7139 C CD2 . TRP D 4 187 ? 168.791 148.474 201.813 1.00 57.25  ? 169 TRP B CD2 1 
ATOM   7140 N NE1 . TRP D 4 187 ? 166.806 147.877 200.972 1.00 61.33  ? 169 TRP B NE1 1 
ATOM   7141 C CE2 . TRP D 4 187 ? 168.136 147.553 200.977 1.00 53.81  ? 169 TRP B CE2 1 
ATOM   7142 C CE3 . TRP D 4 187 ? 170.171 148.361 201.990 1.00 60.89  ? 169 TRP B CE3 1 
ATOM   7143 C CZ2 . TRP D 4 187 ? 168.813 146.534 200.319 1.00 53.98  ? 169 TRP B CZ2 1 
ATOM   7144 C CZ3 . TRP D 4 187 ? 170.840 147.349 201.338 1.00 58.33  ? 169 TRP B CZ3 1 
ATOM   7145 C CH2 . TRP D 4 187 ? 170.161 146.448 200.512 1.00 57.10  ? 169 TRP B CH2 1 
ATOM   7146 N N   . ASP D 4 188 ? 169.283 151.835 205.455 1.00 72.94  ? 170 ASP B N   1 
ATOM   7147 C CA  . ASP D 4 188 ? 169.828 153.058 206.022 1.00 72.97  ? 170 ASP B CA  1 
ATOM   7148 C C   . ASP D 4 188 ? 170.704 153.716 204.967 1.00 72.91  ? 170 ASP B C   1 
ATOM   7149 O O   . ASP D 4 188 ? 171.438 153.039 204.241 1.00 82.09  ? 170 ASP B O   1 
ATOM   7150 C CB  . ASP D 4 188 ? 170.642 152.781 207.289 1.00 71.44  ? 170 ASP B CB  1 
ATOM   7151 C CG  . ASP D 4 188 ? 170.692 153.969 208.222 1.00 76.26  ? 170 ASP B CG  1 
ATOM   7152 O OD1 . ASP D 4 188 ? 169.664 154.666 208.349 1.00 81.57  ? 170 ASP B OD1 1 
ATOM   7153 O OD2 . ASP D 4 188 ? 171.754 154.200 208.836 1.00 77.95  ? 170 ASP B OD2 1 
ATOM   7154 N N   . ILE D 4 189 ? 170.623 155.037 204.878 1.00 68.10  ? 171 ILE B N   1 
ATOM   7155 C CA  . ILE D 4 189 ? 171.221 155.749 203.753 1.00 73.37  ? 171 ILE B CA  1 
ATOM   7156 C C   . ILE D 4 189 ? 172.684 156.089 204.012 1.00 79.37  ? 171 ILE B C   1 
ATOM   7157 O O   . ILE D 4 189 ? 173.536 155.891 203.142 1.00 86.84  ? 171 ILE B O   1 
ATOM   7158 C CB  . ILE D 4 189 ? 170.387 157.005 203.427 1.00 78.73  ? 171 ILE B CB  1 
ATOM   7159 C CG1 . ILE D 4 189 ? 169.085 156.596 202.731 1.00 75.68  ? 171 ILE B CG1 1 
ATOM   7160 C CG2 . ILE D 4 189 ? 171.190 157.977 202.572 1.00 80.40  ? 171 ILE B CG2 1 
ATOM   7161 C CD1 . ILE D 4 189 ? 168.448 157.693 201.906 1.00 78.51  ? 171 ILE B CD1 1 
ATOM   7162 N N   . GLU D 4 190 ? 173.008 156.609 205.200 1.00 74.01  ? 172 GLU B N   1 
ATOM   7163 C CA  . GLU D 4 190 ? 174.396 156.968 205.485 1.00 78.50  ? 172 GLU B CA  1 
ATOM   7164 C C   . GLU D 4 190 ? 175.309 155.750 205.420 1.00 83.66  ? 172 GLU B C   1 
ATOM   7165 O O   . GLU D 4 190 ? 176.384 155.803 204.812 1.00 87.38  ? 172 GLU B O   1 
ATOM   7166 C CB  . GLU D 4 190 ? 174.504 157.644 206.851 1.00 82.09  ? 172 GLU B CB  1 
ATOM   7167 C CG  . GLU D 4 190 ? 173.485 157.171 207.866 1.00 85.66  ? 172 GLU B CG  1 
ATOM   7168 C CD  . GLU D 4 190 ? 172.262 158.059 207.901 1.00 91.30  ? 172 GLU B CD  1 
ATOM   7169 O OE1 . GLU D 4 190 ? 171.953 158.680 206.863 1.00 88.69  ? 172 GLU B OE1 1 
ATOM   7170 O OE2 . GLU D 4 190 ? 171.610 158.136 208.964 1.00 94.41  ? 172 GLU B OE2 1 
ATOM   7171 N N   . THR D 4 191 ? 174.900 154.646 206.035 1.00 84.85  ? 173 THR B N   1 
ATOM   7172 C CA  . THR D 4 191 ? 175.606 153.376 205.935 1.00 84.36  ? 173 THR B CA  1 
ATOM   7173 C C   . THR D 4 191 ? 174.682 152.373 205.260 1.00 88.68  ? 173 THR B C   1 
ATOM   7174 O O   . THR D 4 191 ? 173.604 152.070 205.781 1.00 93.92  ? 173 THR B O   1 
ATOM   7175 C CB  . THR D 4 191 ? 176.037 152.873 207.312 1.00 84.78  ? 173 THR B CB  1 
ATOM   7176 O OG1 . THR D 4 191 ? 174.938 152.980 208.224 1.00 87.99  ? 173 THR B OG1 1 
ATOM   7177 C CG2 . THR D 4 191 ? 177.204 153.695 207.835 1.00 84.64  ? 173 THR B CG2 1 
ATOM   7178 N N   . GLY D 4 192 ? 175.107 151.855 204.112 1.00 86.81  ? 174 GLY B N   1 
ATOM   7179 C CA  . GLY D 4 192 ? 174.251 151.003 203.311 1.00 86.96  ? 174 GLY B CA  1 
ATOM   7180 C C   . GLY D 4 192 ? 174.071 149.610 203.873 1.00 88.85  ? 174 GLY B C   1 
ATOM   7181 O O   . GLY D 4 192 ? 174.573 148.637 203.301 1.00 94.50  ? 174 GLY B O   1 
ATOM   7182 N N   . GLN D 4 193 ? 173.359 149.496 204.990 1.00 67.32  ? 175 GLN B N   1 
ATOM   7183 C CA  . GLN D 4 193 ? 173.118 148.217 205.638 1.00 71.07  ? 175 GLN B CA  1 
ATOM   7184 C C   . GLN D 4 193 ? 171.627 148.022 205.870 1.00 74.36  ? 175 GLN B C   1 
ATOM   7185 O O   . GLN D 4 193 ? 170.914 148.972 206.205 1.00 75.17  ? 175 GLN B O   1 
ATOM   7186 C CB  . GLN D 4 193 ? 173.873 148.127 206.967 1.00 72.12  ? 175 GLN B CB  1 
ATOM   7187 C CG  . GLN D 4 193 ? 175.300 147.617 206.828 1.00 79.23  ? 175 GLN B CG  1 
ATOM   7188 C CD  . GLN D 4 193 ? 176.074 147.679 208.129 1.00 83.34  ? 175 GLN B CD  1 
ATOM   7189 O OE1 . GLN D 4 193 ? 176.963 148.513 208.296 1.00 83.69  ? 175 GLN B OE1 1 
ATOM   7190 N NE2 . GLN D 4 193 ? 175.739 146.792 209.059 1.00 80.50  ? 175 GLN B NE2 1 
ATOM   7191 N N   . GLN D 4 194 ? 171.162 146.787 205.693 1.00 69.70  ? 176 GLN B N   1 
ATOM   7192 C CA  . GLN D 4 194 ? 169.753 146.468 205.903 1.00 66.27  ? 176 GLN B CA  1 
ATOM   7193 C C   . GLN D 4 194 ? 169.428 146.566 207.386 1.00 64.90  ? 176 GLN B C   1 
ATOM   7194 O O   . GLN D 4 194 ? 169.788 145.681 208.168 1.00 64.80  ? 176 GLN B O   1 
ATOM   7195 C CB  . GLN D 4 194 ? 169.432 145.072 205.379 1.00 63.38  ? 176 GLN B CB  1 
ATOM   7196 C CG  . GLN D 4 194 ? 169.726 144.861 203.911 1.00 70.75  ? 176 GLN B CG  1 
ATOM   7197 C CD  . GLN D 4 194 ? 168.992 143.661 203.353 1.00 73.04  ? 176 GLN B CD  1 
ATOM   7198 O OE1 . GLN D 4 194 ? 168.104 143.108 204.001 1.00 69.99  ? 176 GLN B OE1 1 
ATOM   7199 N NE2 . GLN D 4 194 ? 169.359 143.250 202.146 1.00 73.95  ? 176 GLN B NE2 1 
ATOM   7200 N N   . THR D 4 195 ? 168.744 147.640 207.776 1.00 60.90  ? 177 THR B N   1 
ATOM   7201 C CA  . THR D 4 195 ? 168.355 147.786 209.172 1.00 56.72  ? 177 THR B CA  1 
ATOM   7202 C C   . THR D 4 195 ? 167.334 146.729 209.568 1.00 57.85  ? 177 THR B C   1 
ATOM   7203 O O   . THR D 4 195 ? 167.322 146.271 210.716 1.00 58.73  ? 177 THR B O   1 
ATOM   7204 C CB  . THR D 4 195 ? 167.806 149.187 209.428 1.00 61.50  ? 177 THR B CB  1 
ATOM   7205 O OG1 . THR D 4 195 ? 168.509 150.133 208.613 1.00 71.83  ? 177 THR B OG1 1 
ATOM   7206 C CG2 . THR D 4 195 ? 167.981 149.563 210.888 1.00 58.05  ? 177 THR B CG2 1 
ATOM   7207 N N   . THR D 4 196 ? 166.468 146.327 208.639 1.00 65.46  ? 178 THR B N   1 
ATOM   7208 C CA  . THR D 4 196 ? 165.502 145.283 208.962 1.00 64.32  ? 178 THR B CA  1 
ATOM   7209 C C   . THR D 4 196 ? 165.166 144.492 207.705 1.00 71.32  ? 178 THR B C   1 
ATOM   7210 O O   . THR D 4 196 ? 165.070 145.045 206.607 1.00 77.07  ? 178 THR B O   1 
ATOM   7211 C CB  . THR D 4 196 ? 164.237 145.878 209.600 1.00 67.14  ? 178 THR B CB  1 
ATOM   7212 O OG1 . THR D 4 196 ? 164.527 146.283 210.942 1.00 65.80  ? 178 THR B OG1 1 
ATOM   7213 C CG2 . THR D 4 196 ? 163.103 144.867 209.632 1.00 66.52  ? 178 THR B CG2 1 
ATOM   7214 N N   . THR D 4 197 ? 164.993 143.180 207.877 1.00 62.77  ? 179 THR B N   1 
ATOM   7215 C CA  . THR D 4 197 ? 164.680 142.280 206.775 1.00 65.24  ? 179 THR B CA  1 
ATOM   7216 C C   . THR D 4 197 ? 163.423 141.488 207.100 1.00 58.96  ? 179 THR B C   1 
ATOM   7217 O O   . THR D 4 197 ? 163.317 140.901 208.181 1.00 61.78  ? 179 THR B O   1 
ATOM   7218 C CB  . THR D 4 197 ? 165.846 141.328 206.489 1.00 67.37  ? 179 THR B CB  1 
ATOM   7219 O OG1 . THR D 4 197 ? 166.964 142.078 205.997 1.00 69.23  ? 179 THR B OG1 1 
ATOM   7220 C CG2 . THR D 4 197 ? 165.449 140.296 205.450 1.00 64.86  ? 179 THR B CG2 1 
ATOM   7221 N N   . PHE D 4 198 ? 162.477 141.475 206.164 1.00 58.59  ? 180 PHE B N   1 
ATOM   7222 C CA  . PHE D 4 198 ? 161.208 140.773 206.302 1.00 65.13  ? 180 PHE B CA  1 
ATOM   7223 C C   . PHE D 4 198 ? 161.227 139.560 205.383 1.00 69.20  ? 180 PHE B C   1 
ATOM   7224 O O   . PHE D 4 198 ? 161.397 139.705 204.166 1.00 80.56  ? 180 PHE B O   1 
ATOM   7225 C CB  . PHE D 4 198 ? 160.026 141.677 205.944 1.00 67.57  ? 180 PHE B CB  1 
ATOM   7226 C CG  . PHE D 4 198 ? 160.086 143.049 206.557 1.00 67.20  ? 180 PHE B CG  1 
ATOM   7227 C CD1 . PHE D 4 198 ? 160.884 144.037 206.008 1.00 64.07  ? 180 PHE B CD1 1 
ATOM   7228 C CD2 . PHE D 4 198 ? 159.324 143.357 207.668 1.00 66.91  ? 180 PHE B CD2 1 
ATOM   7229 C CE1 . PHE D 4 198 ? 160.933 145.294 206.565 1.00 57.59  ? 180 PHE B CE1 1 
ATOM   7230 C CE2 . PHE D 4 198 ? 159.371 144.614 208.227 1.00 65.09  ? 180 PHE B CE2 1 
ATOM   7231 C CZ  . PHE D 4 198 ? 160.176 145.583 207.674 1.00 61.51  ? 180 PHE B CZ  1 
ATOM   7232 N N   . THR D 4 199 ? 161.050 138.372 205.961 1.00 56.26  ? 181 THR B N   1 
ATOM   7233 C CA  . THR D 4 199 ? 161.033 137.116 205.211 1.00 57.12  ? 181 THR B CA  1 
ATOM   7234 C C   . THR D 4 199 ? 159.808 136.317 205.640 1.00 60.04  ? 181 THR B C   1 
ATOM   7235 O O   . THR D 4 199 ? 159.836 135.636 206.669 1.00 71.52  ? 181 THR B O   1 
ATOM   7236 C CB  . THR D 4 199 ? 162.306 136.302 205.437 1.00 67.66  ? 181 THR B CB  1 
ATOM   7237 O OG1 . THR D 4 199 ? 162.134 135.455 206.580 1.00 70.76  ? 181 THR B OG1 1 
ATOM   7238 C CG2 . THR D 4 199 ? 163.510 137.205 205.664 1.00 68.12  ? 181 THR B CG2 1 
ATOM   7239 N N   . GLY D 4 200 ? 158.735 136.401 204.861 1.00 60.69  ? 182 GLY B N   1 
ATOM   7240 C CA  . GLY D 4 200 ? 157.558 135.601 205.132 1.00 62.41  ? 182 GLY B CA  1 
ATOM   7241 C C   . GLY D 4 200 ? 156.904 135.039 203.888 1.00 63.79  ? 182 GLY B C   1 
ATOM   7242 O O   . GLY D 4 200 ? 155.943 134.270 203.978 1.00 67.99  ? 182 GLY B O   1 
ATOM   7243 N N   . HIS D 4 201 ? 157.419 135.409 202.723 1.00 64.06  ? 183 HIS B N   1 
ATOM   7244 C CA  . HIS D 4 201 ? 156.777 135.090 201.458 1.00 61.20  ? 183 HIS B CA  1 
ATOM   7245 C C   . HIS D 4 201 ? 157.340 133.807 200.858 1.00 67.13  ? 183 HIS B C   1 
ATOM   7246 O O   . HIS D 4 201 ? 158.444 133.366 201.187 1.00 75.63  ? 183 HIS B O   1 
ATOM   7247 C CB  . HIS D 4 201 ? 156.951 136.242 200.468 1.00 62.95  ? 183 HIS B CB  1 
ATOM   7248 C CG  . HIS D 4 201 ? 155.795 137.190 200.431 1.00 64.89  ? 183 HIS B CG  1 
ATOM   7249 N ND1 . HIS D 4 201 ? 154.519 136.796 200.092 1.00 61.64  ? 183 HIS B ND1 1 
ATOM   7250 C CD2 . HIS D 4 201 ? 155.722 138.517 200.689 1.00 67.51  ? 183 HIS B CD2 1 
ATOM   7251 C CE1 . HIS D 4 201 ? 153.710 137.838 200.145 1.00 64.02  ? 183 HIS B CE1 1 
ATOM   7252 N NE2 . HIS D 4 201 ? 154.415 138.895 200.505 1.00 64.08  ? 183 HIS B NE2 1 
ATOM   7253 N N   . THR D 4 202 ? 156.551 133.205 199.964 1.00 69.76  ? 184 THR B N   1 
ATOM   7254 C CA  . THR D 4 202 ? 156.979 132.071 199.141 1.00 66.43  ? 184 THR B CA  1 
ATOM   7255 C C   . THR D 4 202 ? 156.612 132.414 197.700 1.00 66.37  ? 184 THR B C   1 
ATOM   7256 O O   . THR D 4 202 ? 155.561 132.009 197.201 1.00 75.10  ? 184 THR B O   1 
ATOM   7257 C CB  . THR D 4 202 ? 156.330 130.771 199.601 1.00 72.56  ? 184 THR B CB  1 
ATOM   7258 O OG1 . THR D 4 202 ? 154.989 131.032 200.035 1.00 74.57  ? 184 THR B OG1 1 
ATOM   7259 C CG2 . THR D 4 202 ? 157.119 130.159 200.749 1.00 73.89  ? 184 THR B CG2 1 
ATOM   7260 N N   . GLY D 4 203 ? 157.486 133.146 197.035 1.00 69.82  ? 185 GLY B N   1 
ATOM   7261 C CA  . GLY D 4 203 ? 157.232 133.659 195.703 1.00 77.55  ? 185 GLY B CA  1 
ATOM   7262 C C   . GLY D 4 203 ? 157.752 135.078 195.578 1.00 81.02  ? 185 GLY B C   1 
ATOM   7263 O O   . GLY D 4 203 ? 157.988 135.777 196.563 1.00 86.77  ? 185 GLY B O   1 
ATOM   7264 N N   . ASP D 4 204 ? 157.929 135.515 194.334 1.00 76.93  ? 186 ASP B N   1 
ATOM   7265 C CA  . ASP D 4 204 ? 158.539 136.812 194.078 1.00 72.76  ? 186 ASP B CA  1 
ATOM   7266 C C   . ASP D 4 204 ? 157.601 137.942 194.481 1.00 72.30  ? 186 ASP B C   1 
ATOM   7267 O O   . ASP D 4 204 ? 156.433 137.964 194.083 1.00 74.90  ? 186 ASP B O   1 
ATOM   7268 C CB  . ASP D 4 204 ? 158.914 136.940 192.604 1.00 73.57  ? 186 ASP B CB  1 
ATOM   7269 C CG  . ASP D 4 204 ? 159.786 135.801 192.125 1.00 78.18  ? 186 ASP B CG  1 
ATOM   7270 O OD1 . ASP D 4 204 ? 160.241 135.003 192.971 1.00 75.21  ? 186 ASP B OD1 1 
ATOM   7271 O OD2 . ASP D 4 204 ? 160.021 135.705 190.903 1.00 81.89  ? 186 ASP B OD2 1 
ATOM   7272 N N   . VAL D 4 205 ? 158.122 138.888 195.256 1.00 61.19  ? 187 VAL B N   1 
ATOM   7273 C CA  . VAL D 4 205 ? 157.350 140.049 195.684 1.00 61.23  ? 187 VAL B CA  1 
ATOM   7274 C C   . VAL D 4 205 ? 157.377 141.081 194.566 1.00 69.98  ? 187 VAL B C   1 
ATOM   7275 O O   . VAL D 4 205 ? 158.449 141.520 194.138 1.00 78.22  ? 187 VAL B O   1 
ATOM   7276 C CB  . VAL D 4 205 ? 157.904 140.633 196.990 1.00 59.32  ? 187 VAL B CB  1 
ATOM   7277 C CG1 . VAL D 4 205 ? 156.872 141.531 197.646 1.00 62.12  ? 187 VAL B CG1 1 
ATOM   7278 C CG2 . VAL D 4 205 ? 158.320 139.517 197.932 1.00 69.12  ? 187 VAL B CG2 1 
ATOM   7279 N N   . MET D 4 206 ? 156.197 141.471 194.090 1.00 62.33  ? 188 MET B N   1 
ATOM   7280 C CA  . MET D 4 206 ? 156.099 142.325 192.916 1.00 58.18  ? 188 MET B CA  1 
ATOM   7281 C C   . MET D 4 206 ? 155.673 143.752 193.225 1.00 62.40  ? 188 MET B C   1 
ATOM   7282 O O   . MET D 4 206 ? 156.024 144.661 192.467 1.00 68.18  ? 188 MET B O   1 
ATOM   7283 C CB  . MET D 4 206 ? 155.118 141.723 191.904 1.00 66.66  ? 188 MET B CB  1 
ATOM   7284 C CG  . MET D 4 206 ? 155.623 140.463 191.224 1.00 70.29  ? 188 MET B CG  1 
ATOM   7285 S SD  . MET D 4 206 ? 157.149 140.726 190.305 1.00 83.21  ? 188 MET B SD  1 
ATOM   7286 C CE  . MET D 4 206 ? 156.599 141.899 189.068 1.00 74.21  ? 188 MET B CE  1 
ATOM   7287 N N   . SER D 4 207 ? 154.932 143.986 194.306 1.00 62.15  ? 189 SER B N   1 
ATOM   7288 C CA  . SER D 4 207 ? 154.446 145.330 194.586 1.00 61.37  ? 189 SER B CA  1 
ATOM   7289 C C   . SER D 4 207 ? 154.599 145.654 196.064 1.00 67.06  ? 189 SER B C   1 
ATOM   7290 O O   . SER D 4 207 ? 154.566 144.766 196.918 1.00 75.65  ? 189 SER B O   1 
ATOM   7291 C CB  . SER D 4 207 ? 152.980 145.494 194.169 1.00 72.12  ? 189 SER B CB  1 
ATOM   7292 O OG  . SER D 4 207 ? 152.503 146.790 194.487 1.00 71.04  ? 189 SER B OG  1 
ATOM   7293 N N   . LEU D 4 208 ? 154.736 146.946 196.354 1.00 59.75  ? 190 LEU B N   1 
ATOM   7294 C CA  . LEU D 4 208 ? 154.903 147.438 197.713 1.00 56.90  ? 190 LEU B CA  1 
ATOM   7295 C C   . LEU D 4 208 ? 154.211 148.785 197.854 1.00 60.19  ? 190 LEU B C   1 
ATOM   7296 O O   . LEU D 4 208 ? 154.349 149.651 196.987 1.00 67.57  ? 190 LEU B O   1 
ATOM   7297 C CB  . LEU D 4 208 ? 156.385 147.570 198.067 1.00 50.62  ? 190 LEU B CB  1 
ATOM   7298 C CG  . LEU D 4 208 ? 156.719 148.143 199.439 1.00 49.40  ? 190 LEU B CG  1 
ATOM   7299 C CD1 . LEU D 4 208 ? 156.187 147.225 200.519 1.00 59.61  ? 190 LEU B CD1 1 
ATOM   7300 C CD2 . LEU D 4 208 ? 158.215 148.324 199.583 1.00 60.73  ? 190 LEU B CD2 1 
ATOM   7301 N N   . SER D 4 209 ? 153.471 148.962 198.948 1.00 57.48  ? 191 SER B N   1 
ATOM   7302 C CA  . SER D 4 209 ? 152.783 150.220 199.203 1.00 51.06  ? 191 SER B CA  1 
ATOM   7303 C C   . SER D 4 209 ? 152.917 150.596 200.670 1.00 58.67  ? 191 SER B C   1 
ATOM   7304 O O   . SER D 4 209 ? 153.009 149.729 201.546 1.00 65.06  ? 191 SER B O   1 
ATOM   7305 C CB  . SER D 4 209 ? 151.303 150.147 198.821 1.00 58.02  ? 191 SER B CB  1 
ATOM   7306 O OG  . SER D 4 209 ? 150.553 151.112 199.536 1.00 64.47  ? 191 SER B OG  1 
ATOM   7307 N N   . LEU D 4 210 ? 152.905 151.901 200.928 1.00 58.54  ? 192 LEU B N   1 
ATOM   7308 C CA  . LEU D 4 210 ? 153.138 152.463 202.249 1.00 61.61  ? 192 LEU B CA  1 
ATOM   7309 C C   . LEU D 4 210 ? 151.883 153.158 202.761 1.00 58.30  ? 192 LEU B C   1 
ATOM   7310 O O   . LEU D 4 210 ? 151.088 153.696 201.986 1.00 62.76  ? 192 LEU B O   1 
ATOM   7311 C CB  . LEU D 4 210 ? 154.303 153.455 202.224 1.00 56.63  ? 192 LEU B CB  1 
ATOM   7312 C CG  . LEU D 4 210 ? 155.639 152.959 202.774 1.00 58.33  ? 192 LEU B CG  1 
ATOM   7313 C CD1 . LEU D 4 210 ? 156.078 151.690 202.064 1.00 63.27  ? 192 LEU B CD1 1 
ATOM   7314 C CD2 . LEU D 4 210 ? 156.695 154.036 202.642 1.00 61.09  ? 192 LEU B CD2 1 
ATOM   7315 N N   . ALA D 4 211 ? 151.716 153.140 204.079 1.00 57.35  ? 193 ALA B N   1 
ATOM   7316 C CA  . ALA D 4 211 ? 150.546 153.717 204.718 1.00 58.47  ? 193 ALA B CA  1 
ATOM   7317 C C   . ALA D 4 211 ? 150.687 155.228 204.859 1.00 66.47  ? 193 ALA B C   1 
ATOM   7318 O O   . ALA D 4 211 ? 151.798 155.763 204.844 1.00 70.55  ? 193 ALA B O   1 
ATOM   7319 C CB  . ALA D 4 211 ? 150.333 153.080 206.087 1.00 61.70  ? 193 ALA B CB  1 
ATOM   7320 N N   . PRO D 4 212 ? 149.566 155.945 204.985 1.00 70.37  ? 194 PRO B N   1 
ATOM   7321 C CA  . PRO D 4 212 ? 149.650 157.398 205.208 1.00 69.23  ? 194 PRO B CA  1 
ATOM   7322 C C   . PRO D 4 212 ? 150.397 157.781 206.474 1.00 66.55  ? 194 PRO B C   1 
ATOM   7323 O O   . PRO D 4 212 ? 151.033 158.842 206.507 1.00 68.82  ? 194 PRO B O   1 
ATOM   7324 C CB  . PRO D 4 212 ? 148.176 157.831 205.271 1.00 63.37  ? 194 PRO B CB  1 
ATOM   7325 C CG  . PRO D 4 212 ? 147.393 156.566 205.442 1.00 62.24  ? 194 PRO B CG  1 
ATOM   7326 C CD  . PRO D 4 212 ? 148.180 155.507 204.760 1.00 64.49  ? 194 PRO B CD  1 
ATOM   7327 N N   . ASP D 4 213 ? 150.342 156.956 207.515 1.00 69.59  ? 195 ASP B N   1 
ATOM   7328 C CA  . ASP D 4 213 ? 151.005 157.249 208.778 1.00 67.05  ? 195 ASP B CA  1 
ATOM   7329 C C   . ASP D 4 213 ? 152.423 156.694 208.866 1.00 74.20  ? 195 ASP B C   1 
ATOM   7330 O O   . ASP D 4 213 ? 153.052 156.817 209.921 1.00 76.44  ? 195 ASP B O   1 
ATOM   7331 C CB  . ASP D 4 213 ? 150.138 156.748 209.946 1.00 75.23  ? 195 ASP B CB  1 
ATOM   7332 C CG  . ASP D 4 213 ? 150.056 155.225 210.035 1.00 82.27  ? 195 ASP B CG  1 
ATOM   7333 O OD1 . ASP D 4 213 ? 151.050 154.518 209.782 1.00 84.93  ? 195 ASP B OD1 1 
ATOM   7334 O OD2 . ASP D 4 213 ? 148.963 154.726 210.373 1.00 82.80  ? 195 ASP B OD2 1 
ATOM   7335 N N   . THR D 4 214 ? 152.937 156.107 207.783 1.00 80.03  ? 196 THR B N   1 
ATOM   7336 C CA  . THR D 4 214 ? 154.324 155.630 207.685 1.00 79.38  ? 196 THR B CA  1 
ATOM   7337 C C   . THR D 4 214 ? 154.703 154.720 208.854 1.00 79.54  ? 196 THR B C   1 
ATOM   7338 O O   . THR D 4 214 ? 155.788 154.827 209.426 1.00 78.32  ? 196 THR B O   1 
ATOM   7339 C CB  . THR D 4 214 ? 155.314 156.796 207.566 1.00 82.15  ? 196 THR B CB  1 
ATOM   7340 O OG1 . THR D 4 214 ? 154.890 157.901 208.374 1.00 84.18  ? 196 THR B OG1 1 
ATOM   7341 C CG2 . THR D 4 214 ? 155.408 157.261 206.122 1.00 81.80  ? 196 THR B CG2 1 
ATOM   7342 N N   . ARG D 4 215 ? 153.801 153.806 209.206 1.00 75.51  ? 197 ARG B N   1 
ATOM   7343 C CA  . ARG D 4 215 ? 154.046 152.832 210.263 1.00 67.07  ? 197 ARG B CA  1 
ATOM   7344 C C   . ARG D 4 215 ? 153.793 151.394 209.841 1.00 69.20  ? 197 ARG B C   1 
ATOM   7345 O O   . ARG D 4 215 ? 154.373 150.484 210.434 1.00 80.19  ? 197 ARG B O   1 
ATOM   7346 C CB  . ARG D 4 215 ? 153.177 153.142 211.491 1.00 73.47  ? 197 ARG B CB  1 
ATOM   7347 C CG  . ARG D 4 215 ? 153.442 152.259 212.693 1.00 80.51  ? 197 ARG B CG  1 
ATOM   7348 C CD  . ARG D 4 215 ? 152.504 152.606 213.839 1.00 82.02  ? 197 ARG B CD  1 
ATOM   7349 N NE  . ARG D 4 215 ? 152.735 153.951 214.354 1.00 83.45  ? 197 ARG B NE  1 
ATOM   7350 C CZ  . ARG D 4 215 ? 153.657 154.271 215.253 1.00 83.52  ? 197 ARG B CZ  1 
ATOM   7351 N NH1 . ARG D 4 215 ? 154.484 153.366 215.750 1.00 80.52  ? 197 ARG B NH1 1 
ATOM   7352 N NH2 . ARG D 4 215 ? 153.755 155.534 215.659 1.00 82.99  ? 197 ARG B NH2 1 
ATOM   7353 N N   . LEU D 4 216 ? 152.939 151.165 208.847 1.00 53.35  ? 198 LEU B N   1 
ATOM   7354 C CA  . LEU D 4 216 ? 152.674 149.838 208.314 1.00 52.72  ? 198 LEU B CA  1 
ATOM   7355 C C   . LEU D 4 216 ? 152.845 149.874 206.803 1.00 54.29  ? 198 LEU B C   1 
ATOM   7356 O O   . LEU D 4 216 ? 152.753 150.932 206.178 1.00 66.13  ? 198 LEU B O   1 
ATOM   7357 C CB  . LEU D 4 216 ? 151.262 149.358 208.668 1.00 51.50  ? 198 LEU B CB  1 
ATOM   7358 C CG  . LEU D 4 216 ? 150.875 149.351 210.145 1.00 56.08  ? 198 LEU B CG  1 
ATOM   7359 C CD1 . LEU D 4 216 ? 149.372 149.474 210.298 1.00 55.68  ? 198 LEU B CD1 1 
ATOM   7360 C CD2 . LEU D 4 216 ? 151.380 148.090 210.822 1.00 58.43  ? 198 LEU B CD2 1 
ATOM   7361 N N   . PHE D 4 217 ? 153.099 148.710 206.209 1.00 46.46  ? 199 PHE B N   1 
ATOM   7362 C CA  . PHE D 4 217 ? 153.193 148.668 204.755 1.00 43.91  ? 199 PHE B CA  1 
ATOM   7363 C C   . PHE D 4 217 ? 152.765 147.307 204.228 1.00 59.12  ? 199 PHE B C   1 
ATOM   7364 O O   . PHE D 4 217 ? 152.925 146.283 204.897 1.00 63.98  ? 199 PHE B O   1 
ATOM   7365 C CB  . PHE D 4 217 ? 154.600 149.023 204.264 1.00 41.88  ? 199 PHE B CB  1 
ATOM   7366 C CG  . PHE D 4 217 ? 155.626 147.960 204.501 1.00 48.88  ? 199 PHE B CG  1 
ATOM   7367 C CD1 . PHE D 4 217 ? 156.078 147.684 205.777 1.00 62.30  ? 199 PHE B CD1 1 
ATOM   7368 C CD2 . PHE D 4 217 ? 156.162 147.256 203.441 1.00 48.01  ? 199 PHE B CD2 1 
ATOM   7369 C CE1 . PHE D 4 217 ? 157.038 146.718 205.989 1.00 66.45  ? 199 PHE B CE1 1 
ATOM   7370 C CE2 . PHE D 4 217 ? 157.117 146.287 203.647 1.00 54.46  ? 199 PHE B CE2 1 
ATOM   7371 C CZ  . PHE D 4 217 ? 157.554 146.016 204.922 1.00 64.30  ? 199 PHE B CZ  1 
ATOM   7372 N N   . VAL D 4 218 ? 152.227 147.310 203.010 1.00 59.31  ? 200 VAL B N   1 
ATOM   7373 C CA  . VAL D 4 218 ? 151.643 146.121 202.400 1.00 53.63  ? 200 VAL B CA  1 
ATOM   7374 C C   . VAL D 4 218 ? 152.516 145.673 201.238 1.00 58.48  ? 200 VAL B C   1 
ATOM   7375 O O   . VAL D 4 218 ? 153.005 146.497 200.455 1.00 68.25  ? 200 VAL B O   1 
ATOM   7376 C CB  . VAL D 4 218 ? 150.194 146.365 201.937 1.00 39.35  ? 200 VAL B CB  1 
ATOM   7377 C CG1 . VAL D 4 218 ? 149.279 146.503 203.133 1.00 48.81  ? 200 VAL B CG1 1 
ATOM   7378 C CG2 . VAL D 4 218 ? 150.115 147.600 201.072 1.00 44.09  ? 200 VAL B CG2 1 
ATOM   7379 N N   . SER D 4 219 ? 152.721 144.363 201.140 1.00 49.89  ? 201 SER B N   1 
ATOM   7380 C CA  . SER D 4 219 ? 153.527 143.766 200.088 1.00 47.04  ? 201 SER B CA  1 
ATOM   7381 C C   . SER D 4 219 ? 152.704 142.727 199.342 1.00 48.64  ? 201 SER B C   1 
ATOM   7382 O O   . SER D 4 219 ? 151.952 141.957 199.953 1.00 56.72  ? 201 SER B O   1 
ATOM   7383 C CB  . SER D 4 219 ? 154.791 143.122 200.659 1.00 57.48  ? 201 SER B CB  1 
ATOM   7384 O OG  . SER D 4 219 ? 154.481 141.939 201.372 1.00 65.80  ? 201 SER B OG  1 
ATOM   7385 N N   . GLY D 4 220 ? 152.850 142.714 198.020 1.00 54.90  ? 202 GLY B N   1 
ATOM   7386 C CA  . GLY D 4 220 ? 152.155 141.767 197.174 1.00 59.16  ? 202 GLY B CA  1 
ATOM   7387 C C   . GLY D 4 220 ? 153.106 140.965 196.314 1.00 66.84  ? 202 GLY B C   1 
ATOM   7388 O O   . GLY D 4 220 ? 153.946 141.536 195.608 1.00 72.14  ? 202 GLY B O   1 
ATOM   7389 N N   . ALA D 4 221 ? 152.976 139.643 196.357 1.00 70.17  ? 203 ALA B N   1 
ATOM   7390 C CA  . ALA D 4 221 ? 153.947 138.731 195.772 1.00 69.93  ? 203 ALA B CA  1 
ATOM   7391 C C   . ALA D 4 221 ? 153.308 137.899 194.661 1.00 67.28  ? 203 ALA B C   1 
ATOM   7392 O O   . ALA D 4 221 ? 152.162 138.122 194.262 1.00 71.87  ? 203 ALA B O   1 
ATOM   7393 C CB  . ALA D 4 221 ? 154.556 137.838 196.854 1.00 70.18  ? 203 ALA B CB  1 
ATOM   7394 N N   . CYS D 4 222 ? 154.073 136.929 194.166 1.00 68.77  ? 204 CYS B N   1 
ATOM   7395 C CA  . CYS D 4 222 ? 153.692 136.111 193.023 1.00 68.79  ? 204 CYS B CA  1 
ATOM   7396 C C   . CYS D 4 222 ? 152.930 134.852 193.410 1.00 72.94  ? 204 CYS B C   1 
ATOM   7397 O O   . CYS D 4 222 ? 152.648 134.025 192.538 1.00 76.45  ? 204 CYS B O   1 
ATOM   7398 C CB  . CYS D 4 222 ? 154.937 135.724 192.219 1.00 70.20  ? 204 CYS B CB  1 
ATOM   7399 S SG  . CYS D 4 222 ? 154.663 135.511 190.449 1.00 88.70  ? 204 CYS B SG  1 
ATOM   7400 N N   . ASP D 4 223 ? 152.565 134.726 194.692 1.00 69.14  ? 205 ASP B N   1 
ATOM   7401 C CA  . ASP D 4 223 ? 151.892 133.505 195.212 1.00 67.77  ? 205 ASP B CA  1 
ATOM   7402 C C   . ASP D 4 223 ? 150.430 133.791 195.544 1.00 71.13  ? 205 ASP B C   1 
ATOM   7403 O O   . ASP D 4 223 ? 149.825 132.968 196.251 1.00 78.27  ? 205 ASP B O   1 
ATOM   7404 C CB  . ASP D 4 223 ? 152.566 133.033 196.496 1.00 71.94  ? 205 ASP B CB  1 
ATOM   7405 C CG  . ASP D 4 223 ? 152.500 134.070 197.603 1.00 78.03  ? 205 ASP B CG  1 
ATOM   7406 O OD1 . ASP D 4 223 ? 151.996 135.179 197.335 1.00 81.41  ? 205 ASP B OD1 1 
ATOM   7407 O OD2 . ASP D 4 223 ? 152.965 133.769 198.720 1.00 77.45  ? 205 ASP B OD2 1 
ATOM   7408 N N   . ALA D 4 224 ? 149.898 134.917 195.086 1.00 62.73  ? 206 ALA B N   1 
ATOM   7409 C CA  . ALA D 4 224 ? 148.502 135.289 195.312 1.00 65.55  ? 206 ALA B CA  1 
ATOM   7410 C C   . ALA D 4 224 ? 148.196 135.421 196.805 1.00 67.51  ? 206 ALA B C   1 
ATOM   7411 O O   . ALA D 4 224 ? 147.338 134.731 197.360 1.00 71.72  ? 206 ALA B O   1 
ATOM   7412 C CB  . ALA D 4 224 ? 147.555 134.291 194.638 1.00 69.70  ? 206 ALA B CB  1 
ATOM   7413 N N   . SER D 4 225 ? 148.926 136.327 197.449 1.00 59.63  ? 207 SER B N   1 
ATOM   7414 C CA  . SER D 4 225 ? 148.692 136.647 198.848 1.00 62.70  ? 207 SER B CA  1 
ATOM   7415 C C   . SER D 4 225 ? 149.307 138.006 199.145 1.00 64.72  ? 207 SER B C   1 
ATOM   7416 O O   . SER D 4 225 ? 150.409 138.309 198.682 1.00 68.93  ? 207 SER B O   1 
ATOM   7417 C CB  . SER D 4 225 ? 149.278 135.580 199.779 1.00 69.74  ? 207 SER B CB  1 
ATOM   7418 O OG  . SER D 4 225 ? 150.655 135.807 200.021 1.00 72.76  ? 207 SER B OG  1 
ATOM   7419 N N   . ALA D 4 226 ? 148.588 138.815 199.915 1.00 57.67  ? 208 ALA B N   1 
ATOM   7420 C CA  . ALA D 4 226 ? 149.037 140.146 200.300 1.00 56.73  ? 208 ALA B CA  1 
ATOM   7421 C C   . ALA D 4 226 ? 149.330 140.167 201.792 1.00 57.14  ? 208 ALA B C   1 
ATOM   7422 O O   . ALA D 4 226 ? 148.481 139.781 202.599 1.00 61.72  ? 208 ALA B O   1 
ATOM   7423 C CB  . ALA D 4 226 ? 147.989 141.204 199.950 1.00 57.97  ? 208 ALA B CB  1 
ATOM   7424 N N   . LYS D 4 227 ? 150.522 140.623 202.157 1.00 57.89  ? 209 LYS B N   1 
ATOM   7425 C CA  . LYS D 4 227 ? 150.976 140.577 203.540 1.00 58.20  ? 209 LYS B CA  1 
ATOM   7426 C C   . LYS D 4 227 ? 151.128 141.989 204.086 1.00 63.20  ? 209 LYS B C   1 
ATOM   7427 O O   . LYS D 4 227 ? 151.704 142.859 203.422 1.00 69.64  ? 209 LYS B O   1 
ATOM   7428 C CB  . LYS D 4 227 ? 152.300 139.821 203.652 1.00 60.45  ? 209 LYS B CB  1 
ATOM   7429 C CG  . LYS D 4 227 ? 152.202 138.355 203.269 1.00 62.88  ? 209 LYS B CG  1 
ATOM   7430 C CD  . LYS D 4 227 ? 152.994 137.480 204.223 1.00 61.63  ? 209 LYS B CD  1 
ATOM   7431 C CE  . LYS D 4 227 ? 152.643 136.016 204.046 1.00 58.93  ? 209 LYS B CE  1 
ATOM   7432 N NZ  . LYS D 4 227 ? 153.121 135.186 205.184 1.00 60.64  ? 209 LYS B NZ  1 
ATOM   7433 N N   . LEU D 4 228 ? 150.620 142.209 205.295 1.00 56.15  ? 210 LEU B N   1 
ATOM   7434 C CA  . LEU D 4 228 ? 150.735 143.495 205.969 1.00 52.44  ? 210 LEU B CA  1 
ATOM   7435 C C   . LEU D 4 228 ? 151.805 143.400 207.048 1.00 54.53  ? 210 LEU B C   1 
ATOM   7436 O O   . LEU D 4 228 ? 151.734 142.529 207.921 1.00 64.37  ? 210 LEU B O   1 
ATOM   7437 C CB  . LEU D 4 228 ? 149.395 143.906 206.577 1.00 45.01  ? 210 LEU B CB  1 
ATOM   7438 C CG  . LEU D 4 228 ? 149.407 145.064 207.570 1.00 44.44  ? 210 LEU B CG  1 
ATOM   7439 C CD1 . LEU D 4 228 ? 149.548 146.387 206.843 1.00 55.53  ? 210 LEU B CD1 1 
ATOM   7440 C CD2 . LEU D 4 228 ? 148.149 145.046 208.410 1.00 50.43  ? 210 LEU B CD2 1 
ATOM   7441 N N   . TRP D 4 229 ? 152.791 144.292 206.988 1.00 47.13  ? 211 TRP B N   1 
ATOM   7442 C CA  . TRP D 4 229 ? 153.945 144.241 207.868 1.00 52.70  ? 211 TRP B CA  1 
ATOM   7443 C C   . TRP D 4 229 ? 154.061 145.523 208.677 1.00 60.31  ? 211 TRP B C   1 
ATOM   7444 O O   . TRP D 4 229 ? 153.642 146.603 208.237 1.00 70.57  ? 211 TRP B O   1 
ATOM   7445 C CB  . TRP D 4 229 ? 155.251 144.042 207.090 1.00 59.18  ? 211 TRP B CB  1 
ATOM   7446 C CG  . TRP D 4 229 ? 155.179 143.120 205.918 1.00 60.60  ? 211 TRP B CG  1 
ATOM   7447 C CD1 . TRP D 4 229 ? 154.573 143.358 204.723 1.00 59.79  ? 211 TRP B CD1 1 
ATOM   7448 C CD2 . TRP D 4 229 ? 155.778 141.824 205.812 1.00 54.88  ? 211 TRP B CD2 1 
ATOM   7449 N NE1 . TRP D 4 229 ? 154.736 142.283 203.887 1.00 64.57  ? 211 TRP B NE1 1 
ATOM   7450 C CE2 . TRP D 4 229 ? 155.476 141.328 204.533 1.00 60.00  ? 211 TRP B CE2 1 
ATOM   7451 C CE3 . TRP D 4 229 ? 156.531 141.031 206.681 1.00 49.81  ? 211 TRP B CE3 1 
ATOM   7452 C CZ2 . TRP D 4 229 ? 155.897 140.077 204.100 1.00 62.06  ? 211 TRP B CZ2 1 
ATOM   7453 C CZ3 . TRP D 4 229 ? 156.948 139.793 206.251 1.00 56.20  ? 211 TRP B CZ3 1 
ATOM   7454 C CH2 . TRP D 4 229 ? 156.632 139.326 204.973 1.00 62.55  ? 211 TRP B CH2 1 
ATOM   7455 N N   . ASP D 4 230 ? 154.668 145.388 209.854 1.00 64.07  ? 212 ASP B N   1 
ATOM   7456 C CA  . ASP D 4 230 ? 154.959 146.500 210.747 1.00 63.81  ? 212 ASP B CA  1 
ATOM   7457 C C   . ASP D 4 230 ? 156.379 146.980 210.485 1.00 62.66  ? 212 ASP B C   1 
ATOM   7458 O O   . ASP D 4 230 ? 157.313 146.174 210.434 1.00 72.84  ? 212 ASP B O   1 
ATOM   7459 C CB  . ASP D 4 230 ? 154.796 146.079 212.208 1.00 62.47  ? 212 ASP B CB  1 
ATOM   7460 C CG  . ASP D 4 230 ? 154.768 147.259 213.161 1.00 70.73  ? 212 ASP B CG  1 
ATOM   7461 O OD1 . ASP D 4 230 ? 155.571 148.199 212.988 1.00 71.42  ? 212 ASP B OD1 1 
ATOM   7462 O OD2 . ASP D 4 230 ? 153.938 147.244 214.094 1.00 78.07  ? 212 ASP B OD2 1 
ATOM   7463 N N   . VAL D 4 231 ? 156.533 148.293 210.318 1.00 52.44  ? 213 VAL B N   1 
ATOM   7464 C CA  . VAL D 4 231 ? 157.811 148.850 209.888 1.00 49.86  ? 213 VAL B CA  1 
ATOM   7465 C C   . VAL D 4 231 ? 158.863 148.727 210.983 1.00 55.82  ? 213 VAL B C   1 
ATOM   7466 O O   . VAL D 4 231 ? 160.011 148.353 210.718 1.00 66.46  ? 213 VAL B O   1 
ATOM   7467 C CB  . VAL D 4 231 ? 157.619 150.308 209.439 1.00 60.60  ? 213 VAL B CB  1 
ATOM   7468 C CG1 . VAL D 4 231 ? 158.946 150.943 209.124 1.00 59.71  ? 213 VAL B CG1 1 
ATOM   7469 C CG2 . VAL D 4 231 ? 156.720 150.361 208.218 1.00 63.96  ? 213 VAL B CG2 1 
ATOM   7470 N N   . ARG D 4 232 ? 158.498 149.032 212.227 1.00 67.85  ? 214 ARG B N   1 
ATOM   7471 C CA  . ARG D 4 232 ? 159.473 149.043 213.311 1.00 73.98  ? 214 ARG B CA  1 
ATOM   7472 C C   . ARG D 4 232 ? 159.656 147.669 213.950 1.00 75.89  ? 214 ARG B C   1 
ATOM   7473 O O   . ARG D 4 232 ? 160.791 147.232 214.164 1.00 70.43  ? 214 ARG B O   1 
ATOM   7474 C CB  . ARG D 4 232 ? 159.066 150.071 214.371 1.00 75.61  ? 214 ARG B CB  1 
ATOM   7475 C CG  . ARG D 4 232 ? 159.413 151.502 213.997 1.00 75.94  ? 214 ARG B CG  1 
ATOM   7476 C CD  . ARG D 4 232 ? 158.351 152.480 214.465 1.00 76.86  ? 214 ARG B CD  1 
ATOM   7477 N NE  . ARG D 4 232 ? 158.223 153.612 213.555 1.00 84.59  ? 214 ARG B NE  1 
ATOM   7478 C CZ  . ARG D 4 232 ? 157.570 154.731 213.836 1.00 79.64  ? 214 ARG B CZ  1 
ATOM   7479 N NH1 . ARG D 4 232 ? 156.984 154.913 215.008 1.00 76.08  ? 214 ARG B NH1 1 
ATOM   7480 N NH2 . ARG D 4 232 ? 157.504 155.692 212.919 1.00 73.51  ? 214 ARG B NH2 1 
ATOM   7481 N N   . GLU D 4 233 ? 158.555 146.982 214.265 1.00 79.67  ? 215 GLU B N   1 
ATOM   7482 C CA  . GLU D 4 233 ? 158.655 145.689 214.936 1.00 73.52  ? 215 GLU B CA  1 
ATOM   7483 C C   . GLU D 4 233 ? 159.368 144.663 214.064 1.00 76.07  ? 215 GLU B C   1 
ATOM   7484 O O   . GLU D 4 233 ? 160.181 143.874 214.559 1.00 78.45  ? 215 GLU B O   1 
ATOM   7485 C CB  . GLU D 4 233 ? 157.264 145.178 215.318 1.00 50.00  ? 215 GLU B CB  1 
ATOM   7486 C CG  . GLU D 4 233 ? 156.549 146.034 216.350 1.00 50.00  ? 215 GLU B CG  1 
ATOM   7487 C CD  . GLU D 4 233 ? 157.338 146.170 217.639 1.00 50.00  ? 215 GLU B CD  1 
ATOM   7488 O OE1 . GLU D 4 233 ? 157.937 145.167 218.079 1.00 50.00  ? 215 GLU B OE1 1 
ATOM   7489 O OE2 . GLU D 4 233 ? 157.355 147.280 218.213 1.00 50.00  ? 215 GLU B OE2 1 
ATOM   7490 N N   . GLY D 4 234 ? 159.079 144.657 212.767 1.00 71.90  ? 216 GLY B N   1 
ATOM   7491 C CA  . GLY D 4 234 ? 159.753 143.763 211.850 1.00 66.62  ? 216 GLY B CA  1 
ATOM   7492 C C   . GLY D 4 234 ? 159.102 142.415 211.653 1.00 69.52  ? 216 GLY B C   1 
ATOM   7493 O O   . GLY D 4 234 ? 159.757 141.499 211.144 1.00 76.98  ? 216 GLY B O   1 
ATOM   7494 N N   . MET D 4 235 ? 157.838 142.258 212.035 1.00 70.73  ? 217 MET B N   1 
ATOM   7495 C CA  . MET D 4 235 ? 157.148 140.987 211.889 1.00 72.82  ? 217 MET B CA  1 
ATOM   7496 C C   . MET D 4 235 ? 155.784 141.217 211.257 1.00 77.81  ? 217 MET B C   1 
ATOM   7497 O O   . MET D 4 235 ? 155.192 142.291 211.391 1.00 82.69  ? 217 MET B O   1 
ATOM   7498 C CB  . MET D 4 235 ? 157.000 140.265 213.235 1.00 73.97  ? 217 MET B CB  1 
ATOM   7499 C CG  . MET D 4 235 ? 155.845 140.748 214.093 1.00 80.71  ? 217 MET B CG  1 
ATOM   7500 S SD  . MET D 4 235 ? 156.128 140.441 215.846 1.00 96.20  ? 217 MET B SD  1 
ATOM   7501 C CE  . MET D 4 235 ? 154.827 141.426 216.579 1.00 80.17  ? 217 MET B CE  1 
ATOM   7502 N N   . CYS D 4 236 ? 155.299 140.196 210.559 1.00 77.40  ? 218 CYS B N   1 
ATOM   7503 C CA  . CYS D 4 236 ? 154.031 140.295 209.854 1.00 75.93  ? 218 CYS B CA  1 
ATOM   7504 C C   . CYS D 4 236 ? 152.864 140.323 210.833 1.00 74.64  ? 218 CYS B C   1 
ATOM   7505 O O   . CYS D 4 236 ? 152.906 139.718 211.907 1.00 76.94  ? 218 CYS B O   1 
ATOM   7506 C CB  . CYS D 4 236 ? 153.869 139.125 208.886 1.00 77.13  ? 218 CYS B CB  1 
ATOM   7507 S SG  . CYS D 4 236 ? 152.166 138.803 208.388 1.00 90.39  ? 218 CYS B SG  1 
ATOM   7508 N N   . ARG D 4 237 ? 151.813 141.041 210.449 1.00 67.02  ? 219 ARG B N   1 
ATOM   7509 C CA  . ARG D 4 237 ? 150.589 141.130 211.234 1.00 66.85  ? 219 ARG B CA  1 
ATOM   7510 C C   . ARG D 4 237 ? 149.430 140.358 210.631 1.00 68.76  ? 219 ARG B C   1 
ATOM   7511 O O   . ARG D 4 237 ? 148.695 139.695 211.365 1.00 74.12  ? 219 ARG B O   1 
ATOM   7512 C CB  . ARG D 4 237 ? 150.175 142.594 211.407 1.00 75.17  ? 219 ARG B CB  1 
ATOM   7513 C CG  . ARG D 4 237 ? 151.098 143.407 212.292 1.00 74.29  ? 219 ARG B CG  1 
ATOM   7514 C CD  . ARG D 4 237 ? 150.355 143.939 213.505 1.00 72.86  ? 219 ARG B CD  1 
ATOM   7515 N NE  . ARG D 4 237 ? 151.152 144.902 214.253 1.00 75.36  ? 219 ARG B NE  1 
ATOM   7516 C CZ  . ARG D 4 237 ? 152.097 144.574 215.123 1.00 79.41  ? 219 ARG B CZ  1 
ATOM   7517 N NH1 . ARG D 4 237 ? 152.393 143.310 215.377 1.00 73.94  ? 219 ARG B NH1 1 
ATOM   7518 N NH2 . ARG D 4 237 ? 152.762 145.537 215.753 1.00 81.05  ? 219 ARG B NH2 1 
ATOM   7519 N N   . GLN D 4 238 ? 149.243 140.421 209.314 1.00 61.62  ? 220 GLN B N   1 
ATOM   7520 C CA  . GLN D 4 238 ? 148.121 139.747 208.680 1.00 60.00  ? 220 GLN B CA  1 
ATOM   7521 C C   . GLN D 4 238 ? 148.507 139.303 207.277 1.00 67.03  ? 220 GLN B C   1 
ATOM   7522 O O   . GLN D 4 238 ? 149.375 139.900 206.632 1.00 67.97  ? 220 GLN B O   1 
ATOM   7523 C CB  . GLN D 4 238 ? 146.885 140.651 208.617 1.00 58.45  ? 220 GLN B CB  1 
ATOM   7524 C CG  . GLN D 4 238 ? 146.002 140.598 209.847 1.00 62.65  ? 220 GLN B CG  1 
ATOM   7525 C CD  . GLN D 4 238 ? 145.017 141.744 209.899 1.00 66.95  ? 220 GLN B CD  1 
ATOM   7526 O OE1 . GLN D 4 238 ? 144.694 142.254 210.971 1.00 67.04  ? 220 GLN B OE1 1 
ATOM   7527 N NE2 . GLN D 4 238 ? 144.530 142.156 208.737 1.00 70.03  ? 220 GLN B NE2 1 
ATOM   7528 N N   . THR D 4 239 ? 147.839 138.246 206.815 1.00 67.60  ? 221 THR B N   1 
ATOM   7529 C CA  . THR D 4 239 ? 147.987 137.724 205.464 1.00 64.70  ? 221 THR B CA  1 
ATOM   7530 C C   . THR D 4 239 ? 146.607 137.545 204.851 1.00 70.31  ? 221 THR B C   1 
ATOM   7531 O O   . THR D 4 239 ? 145.723 136.949 205.474 1.00 76.48  ? 221 THR B O   1 
ATOM   7532 C CB  . THR D 4 239 ? 148.736 136.390 205.462 1.00 63.53  ? 221 THR B CB  1 
ATOM   7533 O OG1 . THR D 4 239 ? 149.997 136.548 206.124 1.00 72.64  ? 221 THR B OG1 1 
ATOM   7534 C CG2 . THR D 4 239 ? 148.971 135.913 204.040 1.00 64.93  ? 221 THR B CG2 1 
ATOM   7535 N N   . PHE D 4 240 ? 146.424 138.055 203.636 1.00 69.48  ? 222 PHE B N   1 
ATOM   7536 C CA  . PHE D 4 240 ? 145.167 137.949 202.911 1.00 67.98  ? 222 PHE B CA  1 
ATOM   7537 C C   . PHE D 4 240 ? 145.370 137.106 201.663 1.00 68.36  ? 222 PHE B C   1 
ATOM   7538 O O   . PHE D 4 240 ? 146.391 137.231 200.979 1.00 68.27  ? 222 PHE B O   1 
ATOM   7539 C CB  . PHE D 4 240 ? 144.631 139.326 202.508 1.00 70.44  ? 222 PHE B CB  1 
ATOM   7540 C CG  . PHE D 4 240 ? 144.748 140.367 203.581 1.00 65.66  ? 222 PHE B CG  1 
ATOM   7541 C CD1 . PHE D 4 240 ? 143.817 140.439 204.596 1.00 66.18  ? 222 PHE B CD1 1 
ATOM   7542 C CD2 . PHE D 4 240 ? 145.781 141.284 203.562 1.00 66.11  ? 222 PHE B CD2 1 
ATOM   7543 C CE1 . PHE D 4 240 ? 143.920 141.399 205.573 1.00 65.72  ? 222 PHE B CE1 1 
ATOM   7544 C CE2 . PHE D 4 240 ? 145.886 142.245 204.539 1.00 68.12  ? 222 PHE B CE2 1 
ATOM   7545 C CZ  . PHE D 4 240 ? 144.955 142.301 205.545 1.00 67.24  ? 222 PHE B CZ  1 
ATOM   7546 N N   . THR D 4 241 ? 144.387 136.262 201.363 1.00 66.19  ? 223 THR B N   1 
ATOM   7547 C CA  . THR D 4 241 ? 144.407 135.407 200.187 1.00 67.20  ? 223 THR B CA  1 
ATOM   7548 C C   . THR D 4 241 ? 143.070 135.511 199.467 1.00 69.71  ? 223 THR B C   1 
ATOM   7549 O O   . THR D 4 241 ? 142.110 136.100 199.971 1.00 71.68  ? 223 THR B O   1 
ATOM   7550 C CB  . THR D 4 241 ? 144.700 133.947 200.560 1.00 69.41  ? 223 THR B CB  1 
ATOM   7551 O OG1 . THR D 4 241 ? 144.066 133.635 201.806 1.00 72.95  ? 223 THR B OG1 1 
ATOM   7552 C CG2 . THR D 4 241 ? 146.197 133.720 200.688 1.00 63.90  ? 223 THR B CG2 1 
ATOM   7553 N N   . GLY D 4 242 ? 143.011 134.924 198.275 1.00 74.35  ? 224 GLY B N   1 
ATOM   7554 C CA  . GLY D 4 242 ? 141.790 134.943 197.494 1.00 71.09  ? 224 GLY B CA  1 
ATOM   7555 C C   . GLY D 4 242 ? 142.007 135.101 196.004 1.00 67.84  ? 224 GLY B C   1 
ATOM   7556 O O   . GLY D 4 242 ? 141.159 134.697 195.204 1.00 73.12  ? 224 GLY B O   1 
ATOM   7557 N N   . HIS D 4 243 ? 143.134 135.686 195.615 1.00 64.89  ? 225 HIS B N   1 
ATOM   7558 C CA  . HIS D 4 243 ? 143.426 135.872 194.202 1.00 68.68  ? 225 HIS B CA  1 
ATOM   7559 C C   . HIS D 4 243 ? 143.765 134.540 193.541 1.00 74.70  ? 225 HIS B C   1 
ATOM   7560 O O   . HIS D 4 243 ? 144.357 133.648 194.153 1.00 79.50  ? 225 HIS B O   1 
ATOM   7561 C CB  . HIS D 4 243 ? 144.577 136.860 194.024 1.00 72.12  ? 225 HIS B CB  1 
ATOM   7562 C CG  . HIS D 4 243 ? 144.131 138.272 193.808 1.00 77.58  ? 225 HIS B CG  1 
ATOM   7563 N ND1 . HIS D 4 243 ? 143.362 138.653 192.730 1.00 76.19  ? 225 HIS B ND1 1 
ATOM   7564 C CD2 . HIS D 4 243 ? 144.327 139.391 194.544 1.00 78.87  ? 225 HIS B CD2 1 
ATOM   7565 C CE1 . HIS D 4 243 ? 143.116 139.948 192.803 1.00 73.96  ? 225 HIS B CE1 1 
ATOM   7566 N NE2 . HIS D 4 243 ? 143.689 140.420 193.895 1.00 75.80  ? 225 HIS B NE2 1 
ATOM   7567 N N   . GLU D 4 244 ? 143.375 134.411 192.271 1.00 77.13  ? 226 GLU B N   1 
ATOM   7568 C CA  . GLU D 4 244 ? 143.625 133.169 191.547 1.00 73.61  ? 226 GLU B CA  1 
ATOM   7569 C C   . GLU D 4 244 ? 145.084 133.055 191.119 1.00 71.51  ? 226 GLU B C   1 
ATOM   7570 O O   . GLU D 4 244 ? 145.656 131.960 191.134 1.00 73.88  ? 226 GLU B O   1 
ATOM   7571 C CB  . GLU D 4 244 ? 142.700 133.071 190.336 1.00 74.09  ? 226 GLU B CB  1 
ATOM   7572 C CG  . GLU D 4 244 ? 142.646 131.688 189.711 1.00 82.27  ? 226 GLU B CG  1 
ATOM   7573 C CD  . GLU D 4 244 ? 141.476 131.523 188.760 1.00 86.09  ? 226 GLU B CD  1 
ATOM   7574 O OE1 . GLU D 4 244 ? 140.408 132.117 189.021 1.00 83.86  ? 226 GLU B OE1 1 
ATOM   7575 O OE2 . GLU D 4 244 ? 141.624 130.799 187.754 1.00 85.43  ? 226 GLU B OE2 1 
ATOM   7576 N N   . SER D 4 245 ? 145.703 134.170 190.733 1.00 61.43  ? 227 SER B N   1 
ATOM   7577 C CA  . SER D 4 245 ? 147.105 134.154 190.333 1.00 60.32  ? 227 SER B CA  1 
ATOM   7578 C C   . SER D 4 245 ? 147.850 135.343 190.923 1.00 65.16  ? 227 SER B C   1 
ATOM   7579 O O   . SER D 4 245 ? 147.346 136.010 191.832 1.00 68.65  ? 227 SER B O   1 
ATOM   7580 C CB  . SER D 4 245 ? 147.238 134.140 188.811 1.00 72.73  ? 227 SER B CB  1 
ATOM   7581 O OG  . SER D 4 245 ? 148.526 134.567 188.409 1.00 79.64  ? 227 SER B OG  1 
ATOM   7582 N N   . ASP D 4 246 ? 149.050 135.609 190.414 1.00 74.39  ? 228 ASP B N   1 
ATOM   7583 C CA  . ASP D 4 246 ? 149.937 136.588 191.028 1.00 74.23  ? 228 ASP B CA  1 
ATOM   7584 C C   . ASP D 4 246 ? 149.353 137.993 190.959 1.00 75.20  ? 228 ASP B C   1 
ATOM   7585 O O   . ASP D 4 246 ? 148.618 138.343 190.033 1.00 78.22  ? 228 ASP B O   1 
ATOM   7586 C CB  . ASP D 4 246 ? 151.301 136.563 190.344 1.00 75.85  ? 228 ASP B CB  1 
ATOM   7587 C CG  . ASP D 4 246 ? 151.193 136.431 188.842 1.00 82.24  ? 228 ASP B CG  1 
ATOM   7588 O OD1 . ASP D 4 246 ? 150.070 136.210 188.345 1.00 84.82  ? 228 ASP B OD1 1 
ATOM   7589 O OD2 . ASP D 4 246 ? 152.231 136.543 188.159 1.00 83.50  ? 228 ASP B OD2 1 
ATOM   7590 N N   . ILE D 4 247 ? 149.699 138.805 191.956 1.00 66.76  ? 229 ILE B N   1 
ATOM   7591 C CA  . ILE D 4 247 ? 149.259 140.192 192.046 1.00 66.00  ? 229 ILE B CA  1 
ATOM   7592 C C   . ILE D 4 247 ? 150.441 141.100 191.735 1.00 63.84  ? 229 ILE B C   1 
ATOM   7593 O O   . ILE D 4 247 ? 151.584 140.797 192.095 1.00 63.00  ? 229 ILE B O   1 
ATOM   7594 C CB  . ILE D 4 247 ? 148.647 140.504 193.426 1.00 60.98  ? 229 ILE B CB  1 
ATOM   7595 C CG1 . ILE D 4 247 ? 149.710 140.522 194.519 1.00 67.20  ? 229 ILE B CG1 1 
ATOM   7596 C CG2 . ILE D 4 247 ? 147.593 139.477 193.773 1.00 65.78  ? 229 ILE B CG2 1 
ATOM   7597 C CD1 . ILE D 4 247 ? 149.124 140.527 195.916 1.00 71.56  ? 229 ILE B CD1 1 
ATOM   7598 N N   . ASN D 4 248 ? 150.165 142.203 191.036 1.00 71.02  ? 230 ASN B N   1 
ATOM   7599 C CA  . ASN D 4 248 ? 151.212 143.078 190.529 1.00 64.71  ? 230 ASN B CA  1 
ATOM   7600 C C   . ASN D 4 248 ? 151.160 144.507 191.049 1.00 71.71  ? 230 ASN B C   1 
ATOM   7601 O O   . ASN D 4 248 ? 152.190 145.188 191.009 1.00 77.07  ? 230 ASN B O   1 
ATOM   7602 C CB  . ASN D 4 248 ? 151.173 143.125 188.994 1.00 63.31  ? 230 ASN B CB  1 
ATOM   7603 C CG  . ASN D 4 248 ? 151.427 141.776 188.364 1.00 69.05  ? 230 ASN B CG  1 
ATOM   7604 O OD1 . ASN D 4 248 ? 151.836 140.831 189.038 1.00 71.94  ? 230 ASN B OD1 1 
ATOM   7605 N ND2 . ASN D 4 248 ? 151.181 141.674 187.065 1.00 71.21  ? 230 ASN B ND2 1 
ATOM   7606 N N   . ALA D 4 249 ? 150.011 144.986 191.521 1.00 67.19  ? 231 ALA B N   1 
ATOM   7607 C CA  . ALA D 4 249 ? 149.899 146.355 192.000 1.00 63.23  ? 231 ALA B CA  1 
ATOM   7608 C C   . ALA D 4 249 ? 149.023 146.402 193.240 1.00 65.00  ? 231 ALA B C   1 
ATOM   7609 O O   . ALA D 4 249 ? 147.968 145.764 193.288 1.00 71.34  ? 231 ALA B O   1 
ATOM   7610 C CB  . ALA D 4 249 ? 149.324 147.279 190.920 1.00 66.19  ? 231 ALA B CB  1 
ATOM   7611 N N   . ILE D 4 250 ? 149.466 147.161 194.241 1.00 52.66  ? 232 ILE B N   1 
ATOM   7612 C CA  . ILE D 4 250 ? 148.732 147.347 195.487 1.00 57.62  ? 232 ILE B CA  1 
ATOM   7613 C C   . ILE D 4 250 ? 148.724 148.830 195.828 1.00 70.97  ? 232 ILE B C   1 
ATOM   7614 O O   . ILE D 4 250 ? 149.746 149.511 195.692 1.00 79.03  ? 232 ILE B O   1 
ATOM   7615 C CB  . ILE D 4 250 ? 149.347 146.529 196.642 1.00 59.73  ? 232 ILE B CB  1 
ATOM   7616 C CG1 . ILE D 4 250 ? 149.410 145.047 196.279 1.00 69.00  ? 232 ILE B CG1 1 
ATOM   7617 C CG2 . ILE D 4 250 ? 148.542 146.715 197.912 1.00 67.96  ? 232 ILE B CG2 1 
ATOM   7618 C CD1 . ILE D 4 250 ? 149.505 144.127 197.476 1.00 70.27  ? 232 ILE B CD1 1 
ATOM   7619 N N   . CYS D 4 251 ? 147.571 149.333 196.269 1.00 64.33  ? 233 CYS B N   1 
ATOM   7620 C CA  . CYS D 4 251 ? 147.439 150.728 196.663 1.00 54.39  ? 233 CYS B CA  1 
ATOM   7621 C C   . CYS D 4 251 ? 146.663 150.827 197.968 1.00 59.01  ? 233 CYS B C   1 
ATOM   7622 O O   . CYS D 4 251 ? 145.719 150.066 198.195 1.00 68.73  ? 233 CYS B O   1 
ATOM   7623 C CB  . CYS D 4 251 ? 146.737 151.551 195.578 1.00 63.54  ? 233 CYS B CB  1 
ATOM   7624 S SG  . CYS D 4 251 ? 147.124 153.316 195.614 1.00 94.07  ? 233 CYS B SG  1 
ATOM   7625 N N   . PHE D 4 252 ? 147.066 151.767 198.818 1.00 51.37  ? 234 PHE B N   1 
ATOM   7626 C CA  . PHE D 4 252 ? 146.359 152.039 200.062 1.00 47.33  ? 234 PHE B CA  1 
ATOM   7627 C C   . PHE D 4 252 ? 145.214 153.023 199.854 1.00 55.36  ? 234 PHE B C   1 
ATOM   7628 O O   . PHE D 4 252 ? 145.287 153.936 199.027 1.00 62.63  ? 234 PHE B O   1 
ATOM   7629 C CB  . PHE D 4 252 ? 147.307 152.603 201.120 1.00 43.13  ? 234 PHE B CB  1 
ATOM   7630 C CG  . PHE D 4 252 ? 147.767 151.599 202.138 1.00 50.59  ? 234 PHE B CG  1 
ATOM   7631 C CD1 . PHE D 4 252 ? 146.885 151.099 203.078 1.00 54.14  ? 234 PHE B CD1 1 
ATOM   7632 C CD2 . PHE D 4 252 ? 149.084 151.189 202.183 1.00 57.36  ? 234 PHE B CD2 1 
ATOM   7633 C CE1 . PHE D 4 252 ? 147.304 150.189 204.028 1.00 48.83  ? 234 PHE B CE1 1 
ATOM   7634 C CE2 . PHE D 4 252 ? 149.505 150.278 203.131 1.00 52.23  ? 234 PHE B CE2 1 
ATOM   7635 C CZ  . PHE D 4 252 ? 148.612 149.780 204.054 1.00 45.77  ? 234 PHE B CZ  1 
ATOM   7636 N N   . PHE D 4 253 ? 144.148 152.822 200.621 1.00 57.23  ? 235 PHE B N   1 
ATOM   7637 C CA  . PHE D 4 253 ? 143.113 153.830 200.756 1.00 53.98  ? 235 PHE B CA  1 
ATOM   7638 C C   . PHE D 4 253 ? 143.681 155.041 201.494 1.00 62.96  ? 235 PHE B C   1 
ATOM   7639 O O   . PHE D 4 253 ? 144.592 154.903 202.315 1.00 75.22  ? 235 PHE B O   1 
ATOM   7640 C CB  . PHE D 4 253 ? 141.929 153.260 201.531 1.00 61.13  ? 235 PHE B CB  1 
ATOM   7641 C CG  . PHE D 4 253 ? 140.592 153.789 201.100 1.00 53.06  ? 235 PHE B CG  1 
ATOM   7642 C CD1 . PHE D 4 253 ? 140.215 153.775 199.773 1.00 63.03  ? 235 PHE B CD1 1 
ATOM   7643 C CD2 . PHE D 4 253 ? 139.698 154.270 202.037 1.00 50.06  ? 235 PHE B CD2 1 
ATOM   7644 C CE1 . PHE D 4 253 ? 138.976 154.251 199.391 1.00 65.63  ? 235 PHE B CE1 1 
ATOM   7645 C CE2 . PHE D 4 253 ? 138.465 154.743 201.660 1.00 49.79  ? 235 PHE B CE2 1 
ATOM   7646 C CZ  . PHE D 4 253 ? 138.102 154.737 200.337 1.00 54.22  ? 235 PHE B CZ  1 
ATOM   7647 N N   . PRO D 4 254 ? 143.171 156.242 201.215 1.00 53.74  ? 236 PRO B N   1 
ATOM   7648 C CA  . PRO D 4 254 ? 143.637 157.419 201.966 1.00 56.23  ? 236 PRO B CA  1 
ATOM   7649 C C   . PRO D 4 254 ? 143.369 157.328 203.457 1.00 56.48  ? 236 PRO B C   1 
ATOM   7650 O O   . PRO D 4 254 ? 144.080 157.971 204.239 1.00 62.27  ? 236 PRO B O   1 
ATOM   7651 C CB  . PRO D 4 254 ? 142.864 158.580 201.327 1.00 55.75  ? 236 PRO B CB  1 
ATOM   7652 C CG  . PRO D 4 254 ? 142.424 158.077 200.001 1.00 61.28  ? 236 PRO B CG  1 
ATOM   7653 C CD  . PRO D 4 254 ? 142.248 156.601 200.127 1.00 57.95  ? 236 PRO B CD  1 
ATOM   7654 N N   . ASN D 4 255 ? 142.371 156.550 203.876 1.00 57.27  ? 237 ASN B N   1 
ATOM   7655 C CA  . ASN D 4 255 ? 142.093 156.401 205.300 1.00 54.21  ? 237 ASN B CA  1 
ATOM   7656 C C   . ASN D 4 255 ? 143.166 155.570 205.990 1.00 62.86  ? 237 ASN B C   1 
ATOM   7657 O O   . ASN D 4 255 ? 143.548 155.862 207.129 1.00 70.49  ? 237 ASN B O   1 
ATOM   7658 C CB  . ASN D 4 255 ? 140.719 155.764 205.493 1.00 62.47  ? 237 ASN B CB  1 
ATOM   7659 C CG  . ASN D 4 255 ? 140.331 155.641 206.949 1.00 70.83  ? 237 ASN B CG  1 
ATOM   7660 O OD1 . ASN D 4 255 ? 140.872 156.334 207.810 1.00 73.51  ? 237 ASN B OD1 1 
ATOM   7661 N ND2 . ASN D 4 255 ? 139.387 154.753 207.235 1.00 71.62  ? 237 ASN B ND2 1 
ATOM   7662 N N   . GLY D 4 256 ? 143.667 154.538 205.318 1.00 62.46  ? 238 GLY B N   1 
ATOM   7663 C CA  . GLY D 4 256 ? 144.598 153.608 205.919 1.00 59.41  ? 238 GLY B CA  1 
ATOM   7664 C C   . GLY D 4 256 ? 143.960 152.369 206.503 1.00 62.41  ? 238 GLY B C   1 
ATOM   7665 O O   . GLY D 4 256 ? 144.652 151.599 207.179 1.00 65.84  ? 238 GLY B O   1 
ATOM   7666 N N   . ASN D 4 257 ? 142.666 152.156 206.271 1.00 74.80  ? 239 ASN B N   1 
ATOM   7667 C CA  . ASN D 4 257 ? 141.941 151.014 206.811 1.00 79.17  ? 239 ASN B CA  1 
ATOM   7668 C C   . ASN D 4 257 ? 141.476 150.048 205.729 1.00 80.61  ? 239 ASN B C   1 
ATOM   7669 O O   . ASN D 4 257 ? 140.756 149.092 206.034 1.00 85.19  ? 239 ASN B O   1 
ATOM   7670 C CB  . ASN D 4 257 ? 140.740 151.493 207.628 1.00 79.79  ? 239 ASN B CB  1 
ATOM   7671 C CG  . ASN D 4 257 ? 141.139 152.082 208.965 1.00 80.05  ? 239 ASN B CG  1 
ATOM   7672 O OD1 . ASN D 4 257 ? 140.287 152.497 209.750 1.00 80.19  ? 239 ASN B OD1 1 
ATOM   7673 N ND2 . ASN D 4 257 ? 142.438 152.114 209.236 1.00 81.67  ? 239 ASN B ND2 1 
ATOM   7674 N N   . ALA D 4 258 ? 141.865 150.271 204.476 1.00 63.78  ? 240 ALA B N   1 
ATOM   7675 C CA  . ALA D 4 258 ? 141.478 149.391 203.385 1.00 62.55  ? 240 ALA B CA  1 
ATOM   7676 C C   . ALA D 4 258 ? 142.535 149.472 202.297 1.00 61.98  ? 240 ALA B C   1 
ATOM   7677 O O   . ALA D 4 258 ? 143.312 150.427 202.235 1.00 69.24  ? 240 ALA B O   1 
ATOM   7678 C CB  . ALA D 4 258 ? 140.100 149.756 202.824 1.00 62.09  ? 240 ALA B CB  1 
ATOM   7679 N N   . PHE D 4 259 ? 142.563 148.457 201.438 1.00 59.39  ? 241 PHE B N   1 
ATOM   7680 C CA  . PHE D 4 259 ? 143.506 148.482 200.328 1.00 55.92  ? 241 PHE B CA  1 
ATOM   7681 C C   . PHE D 4 259 ? 143.011 147.584 199.205 1.00 63.23  ? 241 PHE B C   1 
ATOM   7682 O O   . PHE D 4 259 ? 142.373 146.556 199.444 1.00 76.07  ? 241 PHE B O   1 
ATOM   7683 C CB  . PHE D 4 259 ? 144.913 148.068 200.773 1.00 57.40  ? 241 PHE B CB  1 
ATOM   7684 C CG  . PHE D 4 259 ? 145.081 146.594 200.986 1.00 63.38  ? 241 PHE B CG  1 
ATOM   7685 C CD1 . PHE D 4 259 ? 144.331 145.924 201.932 1.00 66.32  ? 241 PHE B CD1 1 
ATOM   7686 C CD2 . PHE D 4 259 ? 146.012 145.882 200.254 1.00 64.62  ? 241 PHE B CD2 1 
ATOM   7687 C CE1 . PHE D 4 259 ? 144.498 144.573 202.133 1.00 70.67  ? 241 PHE B CE1 1 
ATOM   7688 C CE2 . PHE D 4 259 ? 146.181 144.532 200.450 1.00 65.01  ? 241 PHE B CE2 1 
ATOM   7689 C CZ  . PHE D 4 259 ? 145.422 143.876 201.388 1.00 70.58  ? 241 PHE B CZ  1 
ATOM   7690 N N   . ALA D 4 260 ? 143.322 147.988 197.976 1.00 54.15  ? 242 ALA B N   1 
ATOM   7691 C CA  . ALA D 4 260 ? 142.896 147.287 196.775 1.00 57.25  ? 242 ALA B CA  1 
ATOM   7692 C C   . ALA D 4 260 ? 144.114 146.820 195.993 1.00 64.38  ? 242 ALA B C   1 
ATOM   7693 O O   . ALA D 4 260 ? 145.107 147.545 195.878 1.00 70.42  ? 242 ALA B O   1 
ATOM   7694 C CB  . ALA D 4 260 ? 142.020 148.179 195.895 1.00 59.76  ? 242 ALA B CB  1 
ATOM   7695 N N   . THR D 4 261 ? 144.030 145.603 195.463 1.00 69.03  ? 243 THR B N   1 
ATOM   7696 C CA  . THR D 4 261 ? 145.123 144.973 194.739 1.00 66.78  ? 243 THR B CA  1 
ATOM   7697 C C   . THR D 4 261 ? 144.639 144.511 193.374 1.00 68.03  ? 243 THR B C   1 
ATOM   7698 O O   . THR D 4 261 ? 143.450 144.245 193.175 1.00 74.54  ? 243 THR B O   1 
ATOM   7699 C CB  . THR D 4 261 ? 145.699 143.770 195.499 1.00 78.24  ? 243 THR B CB  1 
ATOM   7700 O OG1 . THR D 4 261 ? 144.815 142.650 195.362 1.00 81.11  ? 243 THR B OG1 1 
ATOM   7701 C CG2 . THR D 4 261 ? 145.869 144.094 196.973 1.00 77.84  ? 243 THR B CG2 1 
ATOM   7702 N N   . GLY D 4 262 ? 145.577 144.414 192.436 1.00 64.16  ? 244 GLY B N   1 
ATOM   7703 C CA  . GLY D 4 262 ? 145.281 143.963 191.091 1.00 70.78  ? 244 GLY B CA  1 
ATOM   7704 C C   . GLY D 4 262 ? 146.150 142.780 190.712 1.00 71.39  ? 244 GLY B C   1 
ATOM   7705 O O   . GLY D 4 262 ? 147.307 142.683 191.124 1.00 74.03  ? 244 GLY B O   1 
ATOM   7706 N N   . SER D 4 263 ? 145.581 141.878 189.911 1.00 78.15  ? 245 SER B N   1 
ATOM   7707 C CA  . SER D 4 263 ? 146.257 140.636 189.558 1.00 71.93  ? 245 SER B CA  1 
ATOM   7708 C C   . SER D 4 263 ? 146.205 140.369 188.060 1.00 76.08  ? 245 SER B C   1 
ATOM   7709 O O   . SER D 4 263 ? 145.800 141.236 187.280 1.00 86.18  ? 245 SER B O   1 
ATOM   7710 C CB  . SER D 4 263 ? 145.632 139.464 190.314 1.00 74.82  ? 245 SER B CB  1 
ATOM   7711 O OG  . SER D 4 263 ? 144.238 139.404 190.083 1.00 79.32  ? 245 SER B OG  1 
ATOM   7712 N N   . ASP D 4 264 ? 146.617 139.170 187.650 1.00 81.95  ? 246 ASP B N   1 
ATOM   7713 C CA  . ASP D 4 264 ? 146.549 138.742 186.260 1.00 88.47  ? 246 ASP B CA  1 
ATOM   7714 C C   . ASP D 4 264 ? 145.298 137.929 185.960 1.00 86.16  ? 246 ASP B C   1 
ATOM   7715 O O   . ASP D 4 264 ? 145.207 137.322 184.889 1.00 94.44  ? 246 ASP B O   1 
ATOM   7716 C CB  . ASP D 4 264 ? 147.794 137.937 185.889 1.00 89.17  ? 246 ASP B CB  1 
ATOM   7717 C CG  . ASP D 4 264 ? 149.001 138.815 185.647 1.00 93.69  ? 246 ASP B CG  1 
ATOM   7718 O OD1 . ASP D 4 264 ? 149.064 139.914 186.235 1.00 95.25  ? 246 ASP B OD1 1 
ATOM   7719 O OD2 . ASP D 4 264 ? 149.885 138.409 184.865 1.00 93.54  ? 246 ASP B OD2 1 
ATOM   7720 N N   . ASP D 4 265 ? 144.339 137.902 186.879 1.00 75.00  ? 247 ASP B N   1 
ATOM   7721 C CA  . ASP D 4 265 ? 143.061 137.241 186.671 1.00 77.14  ? 247 ASP B CA  1 
ATOM   7722 C C   . ASP D 4 265 ? 142.027 138.161 186.042 1.00 82.25  ? 247 ASP B C   1 
ATOM   7723 O O   . ASP D 4 265 ? 140.852 137.787 185.964 1.00 85.79  ? 247 ASP B O   1 
ATOM   7724 C CB  . ASP D 4 265 ? 142.524 136.707 187.998 1.00 78.43  ? 247 ASP B CB  1 
ATOM   7725 C CG  . ASP D 4 265 ? 143.609 136.130 188.870 1.00 86.26  ? 247 ASP B CG  1 
ATOM   7726 O OD1 . ASP D 4 265 ? 144.590 135.603 188.311 1.00 90.62  ? 247 ASP B OD1 1 
ATOM   7727 O OD2 . ASP D 4 265 ? 143.487 136.209 190.110 1.00 89.72  ? 247 ASP B OD2 1 
ATOM   7728 N N   . ALA D 4 266 ? 142.436 139.355 185.610 1.00 76.59  ? 248 ALA B N   1 
ATOM   7729 C CA  . ALA D 4 266 ? 141.521 140.401 185.153 1.00 79.45  ? 248 ALA B CA  1 
ATOM   7730 C C   . ALA D 4 266 ? 140.536 140.794 186.248 1.00 80.89  ? 248 ALA B C   1 
ATOM   7731 O O   . ALA D 4 266 ? 139.395 141.168 185.968 1.00 87.07  ? 248 ALA B O   1 
ATOM   7732 C CB  . ALA D 4 266 ? 140.775 139.985 183.881 1.00 80.53  ? 248 ALA B CB  1 
ATOM   7733 N N   . THR D 4 267 ? 140.970 140.710 187.504 1.00 69.10  ? 249 THR B N   1 
ATOM   7734 C CA  . THR D 4 267 ? 140.148 141.064 188.651 1.00 71.07  ? 249 THR B CA  1 
ATOM   7735 C C   . THR D 4 267 ? 140.944 141.943 189.603 1.00 75.62  ? 249 THR B C   1 
ATOM   7736 O O   . THR D 4 267 ? 142.148 141.741 189.789 1.00 73.73  ? 249 THR B O   1 
ATOM   7737 C CB  . THR D 4 267 ? 139.657 139.820 189.407 1.00 71.31  ? 249 THR B CB  1 
ATOM   7738 O OG1 . THR D 4 267 ? 140.777 139.135 189.979 1.00 77.98  ? 249 THR B OG1 1 
ATOM   7739 C CG2 . THR D 4 267 ? 138.916 138.876 188.478 1.00 70.75  ? 249 THR B CG2 1 
ATOM   7740 N N   . CYS D 4 268 ? 140.267 142.918 190.200 1.00 83.64  ? 250 CYS B N   1 
ATOM   7741 C CA  . CYS D 4 268 ? 140.803 143.702 191.302 1.00 78.72  ? 250 CYS B CA  1 
ATOM   7742 C C   . CYS D 4 268 ? 140.029 143.367 192.567 1.00 82.43  ? 250 CYS B C   1 
ATOM   7743 O O   . CYS D 4 268 ? 138.857 142.991 192.510 1.00 89.13  ? 250 CYS B O   1 
ATOM   7744 C CB  . CYS D 4 268 ? 140.716 145.203 191.018 1.00 78.90  ? 250 CYS B CB  1 
ATOM   7745 S SG  . CYS D 4 268 ? 142.235 145.937 190.380 1.00 88.56  ? 250 CYS B SG  1 
ATOM   7746 N N   . ARG D 4 269 ? 140.685 143.500 193.715 1.00 75.51  ? 251 ARG B N   1 
ATOM   7747 C CA  . ARG D 4 269 ? 140.059 143.097 194.967 1.00 76.92  ? 251 ARG B CA  1 
ATOM   7748 C C   . ARG D 4 269 ? 140.328 144.129 196.048 1.00 79.02  ? 251 ARG B C   1 
ATOM   7749 O O   . ARG D 4 269 ? 141.475 144.535 196.250 1.00 81.92  ? 251 ARG B O   1 
ATOM   7750 C CB  . ARG D 4 269 ? 140.563 141.720 195.409 1.00 76.58  ? 251 ARG B CB  1 
ATOM   7751 C CG  . ARG D 4 269 ? 139.684 140.582 194.931 1.00 79.04  ? 251 ARG B CG  1 
ATOM   7752 C CD  . ARG D 4 269 ? 140.456 139.287 194.792 1.00 77.40  ? 251 ARG B CD  1 
ATOM   7753 N NE  . ARG D 4 269 ? 139.779 138.354 193.901 1.00 72.05  ? 251 ARG B NE  1 
ATOM   7754 C CZ  . ARG D 4 269 ? 138.762 137.583 194.260 1.00 75.42  ? 251 ARG B CZ  1 
ATOM   7755 N NH1 . ARG D 4 269 ? 138.279 137.605 195.491 1.00 79.62  ? 251 ARG B NH1 1 
ATOM   7756 N NH2 . ARG D 4 269 ? 138.215 136.771 193.361 1.00 76.44  ? 251 ARG B NH2 1 
ATOM   7757 N N   . LEU D 4 270 ? 139.271 144.534 196.749 1.00 77.12  ? 252 LEU B N   1 
ATOM   7758 C CA  . LEU D 4 270 ? 139.351 145.501 197.840 1.00 68.22  ? 252 LEU B CA  1 
ATOM   7759 C C   . LEU D 4 270 ? 139.133 144.766 199.155 1.00 68.86  ? 252 LEU B C   1 
ATOM   7760 O O   . LEU D 4 270 ? 138.034 144.248 199.402 1.00 77.57  ? 252 LEU B O   1 
ATOM   7761 C CB  . LEU D 4 270 ? 138.319 146.612 197.666 1.00 69.19  ? 252 LEU B CB  1 
ATOM   7762 C CG  . LEU D 4 270 ? 138.314 147.685 198.757 1.00 70.82  ? 252 LEU B CG  1 
ATOM   7763 C CD1 . LEU D 4 270 ? 138.988 148.954 198.267 1.00 72.86  ? 252 LEU B CD1 1 
ATOM   7764 C CD2 . LEU D 4 270 ? 136.904 147.977 199.236 1.00 71.32  ? 252 LEU B CD2 1 
ATOM   7765 N N   . PHE D 4 271 ? 140.184 144.723 199.981 1.00 66.10  ? 253 PHE B N   1 
ATOM   7766 C CA  . PHE D 4 271 ? 140.184 144.143 201.316 1.00 67.85  ? 253 PHE B CA  1 
ATOM   7767 C C   . PHE D 4 271 ? 140.205 145.247 202.367 1.00 73.27  ? 253 PHE B C   1 
ATOM   7768 O O   . PHE D 4 271 ? 140.556 146.399 202.086 1.00 80.53  ? 253 PHE B O   1 
ATOM   7769 C CB  . PHE D 4 271 ? 141.405 143.241 201.550 1.00 62.85  ? 253 PHE B CB  1 
ATOM   7770 C CG  . PHE D 4 271 ? 141.764 142.354 200.393 1.00 66.99  ? 253 PHE B CG  1 
ATOM   7771 C CD1 . PHE D 4 271 ? 141.171 141.118 200.242 1.00 67.19  ? 253 PHE B CD1 1 
ATOM   7772 C CD2 . PHE D 4 271 ? 142.732 142.740 199.485 1.00 72.89  ? 253 PHE B CD2 1 
ATOM   7773 C CE1 . PHE D 4 271 ? 141.511 140.297 199.192 1.00 65.78  ? 253 PHE B CE1 1 
ATOM   7774 C CE2 . PHE D 4 271 ? 143.078 141.921 198.433 1.00 73.68  ? 253 PHE B CE2 1 
ATOM   7775 C CZ  . PHE D 4 271 ? 142.466 140.698 198.287 1.00 69.14  ? 253 PHE B CZ  1 
ATOM   7776 N N   . ASP D 4 272 ? 139.863 144.868 203.598 1.00 72.62  ? 254 ASP B N   1 
ATOM   7777 C CA  . ASP D 4 272 ? 139.856 145.771 204.740 1.00 67.84  ? 254 ASP B CA  1 
ATOM   7778 C C   . ASP D 4 272 ? 140.808 145.216 205.791 1.00 73.55  ? 254 ASP B C   1 
ATOM   7779 O O   . ASP D 4 272 ? 140.893 143.999 205.984 1.00 76.62  ? 254 ASP B O   1 
ATOM   7780 C CB  . ASP D 4 272 ? 138.430 145.926 205.304 1.00 69.98  ? 254 ASP B CB  1 
ATOM   7781 C CG  . ASP D 4 272 ? 138.388 146.319 206.784 1.00 81.13  ? 254 ASP B CG  1 
ATOM   7782 O OD1 . ASP D 4 272 ? 139.370 146.863 207.333 1.00 83.60  ? 254 ASP B OD1 1 
ATOM   7783 O OD2 . ASP D 4 272 ? 137.337 146.078 207.412 1.00 85.09  ? 254 ASP B OD2 1 
ATOM   7784 N N   . LEU D 4 273 ? 141.518 146.118 206.472 1.00 66.52  ? 255 LEU B N   1 
ATOM   7785 C CA  . LEU D 4 273 ? 142.523 145.708 207.447 1.00 60.41  ? 255 LEU B CA  1 
ATOM   7786 C C   . LEU D 4 273 ? 141.901 145.198 208.741 1.00 60.71  ? 255 LEU B C   1 
ATOM   7787 O O   . LEU D 4 273 ? 142.352 144.187 209.290 1.00 65.71  ? 255 LEU B O   1 
ATOM   7788 C CB  . LEU D 4 273 ? 143.466 146.872 207.746 1.00 59.88  ? 255 LEU B CB  1 
ATOM   7789 C CG  . LEU D 4 273 ? 144.886 146.764 207.199 1.00 62.69  ? 255 LEU B CG  1 
ATOM   7790 C CD1 . LEU D 4 273 ? 144.871 146.717 205.686 1.00 68.02  ? 255 LEU B CD1 1 
ATOM   7791 C CD2 . LEU D 4 273 ? 145.725 147.927 207.687 1.00 62.82  ? 255 LEU B CD2 1 
ATOM   7792 N N   . ARG D 4 274 ? 140.873 145.880 209.248 1.00 71.33  ? 256 ARG B N   1 
ATOM   7793 C CA  . ARG D 4 274 ? 140.337 145.539 210.561 1.00 71.21  ? 256 ARG B CA  1 
ATOM   7794 C C   . ARG D 4 274 ? 139.496 144.267 210.527 1.00 72.93  ? 256 ARG B C   1 
ATOM   7795 O O   . ARG D 4 274 ? 139.552 143.462 211.462 1.00 78.04  ? 256 ARG B O   1 
ATOM   7796 C CB  . ARG D 4 274 ? 139.518 146.707 211.111 1.00 75.15  ? 256 ARG B CB  1 
ATOM   7797 C CG  . ARG D 4 274 ? 140.287 148.016 211.192 1.00 78.08  ? 256 ARG B CG  1 
ATOM   7798 C CD  . ARG D 4 274 ? 139.966 148.778 212.473 1.00 74.92  ? 256 ARG B CD  1 
ATOM   7799 N NE  . ARG D 4 274 ? 138.610 149.317 212.500 1.00 74.51  ? 256 ARG B NE  1 
ATOM   7800 C CZ  . ARG D 4 274 ? 138.129 150.217 211.651 1.00 78.75  ? 256 ARG B CZ  1 
ATOM   7801 N NH1 . ARG D 4 274 ? 138.882 150.748 210.701 1.00 82.26  ? 256 ARG B NH1 1 
ATOM   7802 N NH2 . ARG D 4 274 ? 136.863 150.604 211.766 1.00 75.81  ? 256 ARG B NH2 1 
ATOM   7803 N N   . ALA D 4 275 ? 138.712 144.066 209.467 1.00 69.29  ? 257 ALA B N   1 
ATOM   7804 C CA  . ALA D 4 275 ? 137.890 142.866 209.366 1.00 67.14  ? 257 ALA B CA  1 
ATOM   7805 C C   . ALA D 4 275 ? 138.676 141.654 208.889 1.00 72.54  ? 257 ALA B C   1 
ATOM   7806 O O   . ALA D 4 275 ? 138.236 140.523 209.116 1.00 78.44  ? 257 ALA B O   1 
ATOM   7807 C CB  . ALA D 4 275 ? 136.706 143.109 208.430 1.00 71.99  ? 257 ALA B CB  1 
ATOM   7808 N N   . ASP D 4 276 ? 139.813 141.868 208.225 1.00 82.54  ? 258 ASP B N   1 
ATOM   7809 C CA  . ASP D 4 276 ? 140.719 140.793 207.817 1.00 84.67  ? 258 ASP B CA  1 
ATOM   7810 C C   . ASP D 4 276 ? 140.050 139.832 206.834 1.00 82.40  ? 258 ASP B C   1 
ATOM   7811 O O   . ASP D 4 276 ? 140.082 138.612 207.004 1.00 88.79  ? 258 ASP B O   1 
ATOM   7812 C CB  . ASP D 4 276 ? 141.260 140.043 209.038 1.00 89.00  ? 258 ASP B CB  1 
ATOM   7813 C CG  . ASP D 4 276 ? 142.465 139.184 208.710 1.00 93.53  ? 258 ASP B CG  1 
ATOM   7814 O OD1 . ASP D 4 276 ? 143.416 139.701 208.090 1.00 92.98  ? 258 ASP B OD1 1 
ATOM   7815 O OD2 . ASP D 4 276 ? 142.461 137.990 209.074 1.00 95.10  ? 258 ASP B OD2 1 
ATOM   7816 N N   . GLN D 4 277 ? 139.444 140.393 205.792 1.00 69.42  ? 259 GLN B N   1 
ATOM   7817 C CA  . GLN D 4 277 ? 138.905 139.601 204.690 1.00 69.45  ? 259 GLN B CA  1 
ATOM   7818 C C   . GLN D 4 277 ? 138.595 140.543 203.536 1.00 74.30  ? 259 GLN B C   1 
ATOM   7819 O O   . GLN D 4 277 ? 138.730 141.765 203.650 1.00 81.54  ? 259 GLN B O   1 
ATOM   7820 C CB  . GLN D 4 277 ? 137.666 138.804 205.100 1.00 72.96  ? 259 GLN B CB  1 
ATOM   7821 C CG  . GLN D 4 277 ? 136.505 139.641 205.572 1.00 75.46  ? 259 GLN B CG  1 
ATOM   7822 C CD  . GLN D 4 277 ? 135.561 138.853 206.452 1.00 81.10  ? 259 GLN B CD  1 
ATOM   7823 O OE1 . GLN D 4 277 ? 134.465 139.309 206.771 1.00 82.48  ? 259 GLN B OE1 1 
ATOM   7824 N NE2 . GLN D 4 277 ? 135.982 137.658 206.848 1.00 78.01  ? 259 GLN B NE2 1 
ATOM   7825 N N   . GLU D 4 278 ? 138.175 139.961 202.418 1.00 87.13  ? 260 GLU B N   1 
ATOM   7826 C CA  . GLU D 4 278 ? 137.880 140.733 201.223 1.00 88.16  ? 260 GLU B CA  1 
ATOM   7827 C C   . GLU D 4 278 ? 136.512 141.392 201.329 1.00 86.84  ? 260 GLU B C   1 
ATOM   7828 O O   . GLU D 4 278 ? 135.612 140.904 202.019 1.00 90.08  ? 260 GLU B O   1 
ATOM   7829 C CB  . GLU D 4 278 ? 137.948 139.844 199.979 1.00 90.28  ? 260 GLU B CB  1 
ATOM   7830 C CG  . GLU D 4 278 ? 136.608 139.348 199.470 1.00 94.80  ? 260 GLU B CG  1 
ATOM   7831 C CD  . GLU D 4 278 ? 136.707 138.737 198.087 1.00 96.21  ? 260 GLU B CD  1 
ATOM   7832 O OE1 . GLU D 4 278 ? 137.818 138.731 197.516 1.00 95.07  ? 260 GLU B OE1 1 
ATOM   7833 O OE2 . GLU D 4 278 ? 135.674 138.261 197.570 1.00 98.13  ? 260 GLU B OE2 1 
ATOM   7834 N N   . LEU D 4 279 ? 136.368 142.524 200.647 1.00 82.72  ? 261 LEU B N   1 
ATOM   7835 C CA  . LEU D 4 279 ? 135.118 143.271 200.638 1.00 86.73  ? 261 LEU B CA  1 
ATOM   7836 C C   . LEU D 4 279 ? 134.509 143.374 199.251 1.00 88.14  ? 261 LEU B C   1 
ATOM   7837 O O   . LEU D 4 279 ? 133.311 143.116 199.090 1.00 90.16  ? 261 LEU B O   1 
ATOM   7838 C CB  . LEU D 4 279 ? 135.332 144.675 201.222 1.00 91.14  ? 261 LEU B CB  1 
ATOM   7839 C CG  . LEU D 4 279 ? 135.264 144.778 202.745 1.00 87.15  ? 261 LEU B CG  1 
ATOM   7840 C CD1 . LEU D 4 279 ? 135.509 146.204 203.195 1.00 85.61  ? 261 LEU B CD1 1 
ATOM   7841 C CD2 . LEU D 4 279 ? 133.923 144.277 203.246 1.00 89.42  ? 261 LEU B CD2 1 
ATOM   7842 N N   . MET D 4 280 ? 135.290 143.743 198.237 1.00 88.09  ? 262 MET B N   1 
ATOM   7843 C CA  . MET D 4 280 ? 134.738 143.872 196.892 1.00 84.75  ? 262 MET B CA  1 
ATOM   7844 C C   . MET D 4 280 ? 135.635 143.232 195.844 1.00 85.23  ? 262 MET B C   1 
ATOM   7845 O O   . MET D 4 280 ? 136.852 143.122 196.010 1.00 88.46  ? 262 MET B O   1 
ATOM   7846 C CB  . MET D 4 280 ? 134.485 145.332 196.495 1.00 86.92  ? 262 MET B CB  1 
ATOM   7847 C CG  . MET D 4 280 ? 133.345 145.477 195.490 1.00 90.50  ? 262 MET B CG  1 
ATOM   7848 S SD  . MET D 4 280 ? 131.738 145.890 196.178 1.00 102.15 ? 262 MET B SD  1 
ATOM   7849 C CE  . MET D 4 280 ? 132.183 147.294 197.182 1.00 92.46  ? 262 MET B CE  1 
ATOM   7850 N N   . THR D 4 281 ? 135.000 142.836 194.740 1.00 75.88  ? 263 THR B N   1 
ATOM   7851 C CA  . THR D 4 281 ? 135.670 142.288 193.568 1.00 75.22  ? 263 THR B CA  1 
ATOM   7852 C C   . THR D 4 281 ? 135.240 143.087 192.347 1.00 74.21  ? 263 THR B C   1 
ATOM   7853 O O   . THR D 4 281 ? 134.042 143.191 192.063 1.00 74.55  ? 263 THR B O   1 
ATOM   7854 C CB  . THR D 4 281 ? 135.325 140.809 193.378 1.00 79.30  ? 263 THR B CB  1 
ATOM   7855 O OG1 . THR D 4 281 ? 133.959 140.589 193.747 1.00 83.16  ? 263 THR B OG1 1 
ATOM   7856 C CG2 . THR D 4 281 ? 136.214 139.942 194.245 1.00 79.34  ? 263 THR B CG2 1 
ATOM   7857 N N   . TYR D 4 282 ? 136.210 143.644 191.628 1.00 75.40  ? 264 TYR B N   1 
ATOM   7858 C CA  . TYR D 4 282 ? 135.973 144.414 190.412 1.00 74.54  ? 264 TYR B CA  1 
ATOM   7859 C C   . TYR D 4 282 ? 136.421 143.573 189.224 1.00 77.62  ? 264 TYR B C   1 
ATOM   7860 O O   . TYR D 4 282 ? 137.616 143.302 189.068 1.00 78.10  ? 264 TYR B O   1 
ATOM   7861 C CB  . TYR D 4 282 ? 136.723 145.743 190.452 1.00 73.00  ? 264 TYR B CB  1 
ATOM   7862 C CG  . TYR D 4 282 ? 136.462 146.563 191.692 1.00 76.68  ? 264 TYR B CG  1 
ATOM   7863 C CD1 . TYR D 4 282 ? 135.169 146.867 192.088 1.00 79.41  ? 264 TYR B CD1 1 
ATOM   7864 C CD2 . TYR D 4 282 ? 137.509 147.026 192.473 1.00 77.41  ? 264 TYR B CD2 1 
ATOM   7865 C CE1 . TYR D 4 282 ? 134.928 147.615 193.220 1.00 77.76  ? 264 TYR B CE1 1 
ATOM   7866 C CE2 . TYR D 4 282 ? 137.276 147.769 193.608 1.00 74.49  ? 264 TYR B CE2 1 
ATOM   7867 C CZ  . TYR D 4 282 ? 135.985 148.060 193.977 1.00 75.93  ? 264 TYR B CZ  1 
ATOM   7868 O OH  . TYR D 4 282 ? 135.750 148.805 195.108 1.00 83.35  ? 264 TYR B OH  1 
ATOM   7869 N N   . SER D 4 283 ? 135.466 143.166 188.391 1.00 84.38  ? 265 SER B N   1 
ATOM   7870 C CA  . SER D 4 283 ? 135.767 142.340 187.231 1.00 83.48  ? 265 SER B CA  1 
ATOM   7871 C C   . SER D 4 283 ? 134.571 142.343 186.294 1.00 83.67  ? 265 SER B C   1 
ATOM   7872 O O   . SER D 4 283 ? 133.420 142.390 186.735 1.00 81.38  ? 265 SER B O   1 
ATOM   7873 C CB  . SER D 4 283 ? 136.113 140.904 187.637 1.00 89.63  ? 265 SER B CB  1 
ATOM   7874 O OG  . SER D 4 283 ? 136.171 140.054 186.505 1.00 91.59  ? 265 SER B OG  1 
ATOM   7875 N N   . HIS D 4 284 ? 134.859 142.287 184.995 1.00 93.59  ? 266 HIS B N   1 
ATOM   7876 C CA  . HIS D 4 284 ? 133.827 142.205 183.974 1.00 95.07  ? 266 HIS B CA  1 
ATOM   7877 C C   . HIS D 4 284 ? 134.225 141.153 182.949 1.00 93.57  ? 266 HIS B C   1 
ATOM   7878 O O   . HIS D 4 284 ? 135.402 140.817 182.798 1.00 94.98  ? 266 HIS B O   1 
ATOM   7879 C CB  . HIS D 4 284 ? 133.589 143.556 183.290 1.00 96.94  ? 266 HIS B CB  1 
ATOM   7880 C CG  . HIS D 4 284 ? 132.177 143.760 182.838 1.00 97.62  ? 266 HIS B CG  1 
ATOM   7881 N ND1 . HIS D 4 284 ? 131.710 143.304 181.624 1.00 96.56  ? 266 HIS B ND1 1 
ATOM   7882 C CD2 . HIS D 4 284 ? 131.126 144.363 183.442 1.00 96.42  ? 266 HIS B CD2 1 
ATOM   7883 C CE1 . HIS D 4 284 ? 130.434 143.622 181.498 1.00 96.90  ? 266 HIS B CE1 1 
ATOM   7884 N NE2 . HIS D 4 284 ? 130.056 144.265 182.588 1.00 96.99  ? 266 HIS B NE2 1 
ATOM   7885 N N   . ASP D 4 285 ? 133.220 140.638 182.238 1.00 84.09  ? 267 ASP B N   1 
ATOM   7886 C CA  . ASP D 4 285 ? 133.447 139.510 181.342 1.00 83.60  ? 267 ASP B CA  1 
ATOM   7887 C C   . ASP D 4 285 ? 134.202 139.915 180.082 1.00 81.90  ? 267 ASP B C   1 
ATOM   7888 O O   . ASP D 4 285 ? 134.979 139.116 179.548 1.00 84.26  ? 267 ASP B O   1 
ATOM   7889 C CB  . ASP D 4 285 ? 132.115 138.862 180.974 1.00 83.97  ? 267 ASP B CB  1 
ATOM   7890 C CG  . ASP D 4 285 ? 131.194 138.711 182.167 1.00 86.69  ? 267 ASP B CG  1 
ATOM   7891 O OD1 . ASP D 4 285 ? 131.401 137.773 182.965 1.00 86.48  ? 267 ASP B OD1 1 
ATOM   7892 O OD2 . ASP D 4 285 ? 130.263 139.531 182.309 1.00 84.98  ? 267 ASP B OD2 1 
ATOM   7893 N N   . ASN D 4 286 ? 133.986 141.135 179.588 1.00 78.51  ? 268 ASN B N   1 
ATOM   7894 C CA  . ASN D 4 286 ? 134.626 141.551 178.344 1.00 79.35  ? 268 ASN B CA  1 
ATOM   7895 C C   . ASN D 4 286 ? 136.141 141.616 178.489 1.00 84.36  ? 268 ASN B C   1 
ATOM   7896 O O   . ASN D 4 286 ? 136.876 141.205 177.583 1.00 86.46  ? 268 ASN B O   1 
ATOM   7897 C CB  . ASN D 4 286 ? 134.074 142.902 177.895 1.00 82.15  ? 268 ASN B CB  1 
ATOM   7898 C CG  . ASN D 4 286 ? 132.563 142.968 177.970 1.00 89.51  ? 268 ASN B CG  1 
ATOM   7899 O OD1 . ASN D 4 286 ? 132.002 143.622 178.849 1.00 91.37  ? 268 ASN B OD1 1 
ATOM   7900 N ND2 . ASN D 4 286 ? 131.894 142.288 177.046 1.00 86.93  ? 268 ASN B ND2 1 
ATOM   7901 N N   . ILE D 4 287 ? 136.626 142.128 179.613 1.00 87.14  ? 269 ILE B N   1 
ATOM   7902 C CA  . ILE D 4 287 ? 138.060 142.286 179.826 1.00 83.25  ? 269 ILE B CA  1 
ATOM   7903 C C   . ILE D 4 287 ? 138.645 140.971 180.322 1.00 85.09  ? 269 ILE B C   1 
ATOM   7904 O O   . ILE D 4 287 ? 138.158 140.388 181.297 1.00 87.88  ? 269 ILE B O   1 
ATOM   7905 C CB  . ILE D 4 287 ? 138.340 143.429 180.815 1.00 80.24  ? 269 ILE B CB  1 
ATOM   7906 C CG1 . ILE D 4 287 ? 137.302 143.426 181.938 1.00 81.02  ? 269 ILE B CG1 1 
ATOM   7907 C CG2 . ILE D 4 287 ? 138.350 144.765 180.093 1.00 85.12  ? 269 ILE B CG2 1 
ATOM   7908 C CD1 . ILE D 4 287 ? 137.438 144.584 182.896 1.00 84.25  ? 269 ILE B CD1 1 
ATOM   7909 N N   . ILE D 4 288 ? 139.689 140.500 179.645 1.00 83.31  ? 270 ILE B N   1 
ATOM   7910 C CA  . ILE D 4 288 ? 140.381 139.277 180.035 1.00 79.39  ? 270 ILE B CA  1 
ATOM   7911 C C   . ILE D 4 288 ? 141.868 139.488 180.266 1.00 79.08  ? 270 ILE B C   1 
ATOM   7912 O O   . ILE D 4 288 ? 142.535 138.569 180.766 1.00 80.05  ? 270 ILE B O   1 
ATOM   7913 C CB  . ILE D 4 288 ? 140.169 138.154 178.999 1.00 79.83  ? 270 ILE B CB  1 
ATOM   7914 C CG1 . ILE D 4 288 ? 140.515 138.652 177.596 1.00 82.17  ? 270 ILE B CG1 1 
ATOM   7915 C CG2 . ILE D 4 288 ? 138.738 137.647 179.050 1.00 81.66  ? 270 ILE B CG2 1 
ATOM   7916 C CD1 . ILE D 4 288 ? 140.489 137.570 176.541 1.00 82.80  ? 270 ILE B CD1 1 
ATOM   7917 N N   . CYS D 4 289 ? 142.413 140.650 179.921 1.00 81.76  ? 271 CYS B N   1 
ATOM   7918 C CA  . CYS D 4 289 ? 143.826 140.923 180.119 1.00 81.07  ? 271 CYS B CA  1 
ATOM   7919 C C   . CYS D 4 289 ? 144.110 141.246 181.584 1.00 88.00  ? 271 CYS B C   1 
ATOM   7920 O O   . CYS D 4 289 ? 143.204 141.488 182.386 1.00 95.28  ? 271 CYS B O   1 
ATOM   7921 C CB  . CYS D 4 289 ? 144.275 142.075 179.224 1.00 82.93  ? 271 CYS B CB  1 
ATOM   7922 S SG  . CYS D 4 289 ? 143.528 143.666 179.639 1.00 96.98  ? 271 CYS B SG  1 
ATOM   7923 N N   . GLY D 4 290 ? 145.394 141.254 181.930 1.00 75.28  ? 272 GLY B N   1 
ATOM   7924 C CA  . GLY D 4 290 ? 145.810 141.507 183.291 1.00 73.12  ? 272 GLY B CA  1 
ATOM   7925 C C   . GLY D 4 290 ? 145.818 142.982 183.643 1.00 71.62  ? 272 GLY B C   1 
ATOM   7926 O O   . GLY D 4 290 ? 145.562 143.860 182.820 1.00 75.92  ? 272 GLY B O   1 
ATOM   7927 N N   . ILE D 4 291 ? 146.123 143.250 184.910 1.00 60.15  ? 273 ILE B N   1 
ATOM   7928 C CA  . ILE D 4 291 ? 146.183 144.603 185.450 1.00 60.66  ? 273 ILE B CA  1 
ATOM   7929 C C   . ILE D 4 291 ? 147.618 144.889 185.864 1.00 57.77  ? 273 ILE B C   1 
ATOM   7930 O O   . ILE D 4 291 ? 148.220 144.115 186.616 1.00 68.39  ? 273 ILE B O   1 
ATOM   7931 C CB  . ILE D 4 291 ? 145.219 144.777 186.635 1.00 57.94  ? 273 ILE B CB  1 
ATOM   7932 C CG1 . ILE D 4 291 ? 143.899 144.067 186.337 1.00 61.52  ? 273 ILE B CG1 1 
ATOM   7933 C CG2 . ILE D 4 291 ? 144.989 146.249 186.921 1.00 64.21  ? 273 ILE B CG2 1 
ATOM   7934 C CD1 . ILE D 4 291 ? 142.926 144.076 187.483 1.00 65.22  ? 273 ILE B CD1 1 
ATOM   7935 N N   . THR D 4 292 ? 148.163 146.000 185.374 1.00 42.50  ? 274 THR B N   1 
ATOM   7936 C CA  . THR D 4 292 ? 149.562 146.332 185.599 1.00 49.78  ? 274 THR B CA  1 
ATOM   7937 C C   . THR D 4 292 ? 149.772 147.432 186.628 1.00 53.74  ? 274 THR B C   1 
ATOM   7938 O O   . THR D 4 292 ? 150.851 147.502 187.225 1.00 59.10  ? 274 THR B O   1 
ATOM   7939 C CB  . THR D 4 292 ? 150.224 146.752 184.284 1.00 53.64  ? 274 THR B CB  1 
ATOM   7940 O OG1 . THR D 4 292 ? 149.409 147.731 183.630 1.00 53.55  ? 274 THR B OG1 1 
ATOM   7941 C CG2 . THR D 4 292 ? 150.392 145.551 183.372 1.00 57.30  ? 274 THR B CG2 1 
ATOM   7942 N N   . SER D 4 293 ? 148.783 148.292 186.853 1.00 69.64  ? 275 SER B N   1 
ATOM   7943 C CA  . SER D 4 293 ? 148.915 149.356 187.836 1.00 73.36  ? 275 SER B CA  1 
ATOM   7944 C C   . SER D 4 293 ? 147.545 149.685 188.405 1.00 73.64  ? 275 SER B C   1 
ATOM   7945 O O   . SER D 4 293 ? 146.531 149.591 187.711 1.00 83.59  ? 275 SER B O   1 
ATOM   7946 C CB  . SER D 4 293 ? 149.550 150.611 187.227 1.00 77.79  ? 275 SER B CB  1 
ATOM   7947 O OG  . SER D 4 293 ? 150.685 150.282 186.445 1.00 87.43  ? 275 SER B OG  1 
ATOM   7948 N N   . VAL D 4 294 ? 147.524 150.075 189.675 1.00 52.70  ? 276 VAL B N   1 
ATOM   7949 C CA  . VAL D 4 294 ? 146.293 150.434 190.367 1.00 56.32  ? 276 VAL B CA  1 
ATOM   7950 C C   . VAL D 4 294 ? 146.565 151.647 191.245 1.00 66.57  ? 276 VAL B C   1 
ATOM   7951 O O   . VAL D 4 294 ? 147.592 151.710 191.929 1.00 77.26  ? 276 VAL B O   1 
ATOM   7952 C CB  . VAL D 4 294 ? 145.754 149.254 191.201 1.00 61.14  ? 276 VAL B CB  1 
ATOM   7953 C CG1 . VAL D 4 294 ? 144.782 149.736 192.255 1.00 67.38  ? 276 VAL B CG1 1 
ATOM   7954 C CG2 . VAL D 4 294 ? 145.087 148.230 190.302 1.00 65.54  ? 276 VAL B CG2 1 
ATOM   7955 N N   . SER D 4 295 ? 145.651 152.616 191.223 1.00 67.82  ? 277 SER B N   1 
ATOM   7956 C CA  . SER D 4 295 ? 145.777 153.781 192.087 1.00 64.20  ? 277 SER B CA  1 
ATOM   7957 C C   . SER D 4 295 ? 144.393 154.274 192.483 1.00 65.14  ? 277 SER B C   1 
ATOM   7958 O O   . SER D 4 295 ? 143.391 153.973 191.829 1.00 71.21  ? 277 SER B O   1 
ATOM   7959 C CB  . SER D 4 295 ? 146.572 154.903 191.417 1.00 68.07  ? 277 SER B CB  1 
ATOM   7960 O OG  . SER D 4 295 ? 146.643 156.040 192.256 1.00 75.21  ? 277 SER B OG  1 
ATOM   7961 N N   . PHE D 4 296 ? 144.349 155.031 193.574 1.00 53.60  ? 278 PHE B N   1 
ATOM   7962 C CA  . PHE D 4 296 ? 143.109 155.542 194.133 1.00 52.70  ? 278 PHE B CA  1 
ATOM   7963 C C   . PHE D 4 296 ? 143.009 157.044 193.907 1.00 63.74  ? 278 PHE B C   1 
ATOM   7964 O O   . PHE D 4 296 ? 144.020 157.735 193.755 1.00 73.39  ? 278 PHE B O   1 
ATOM   7965 C CB  . PHE D 4 296 ? 143.014 155.253 195.635 1.00 56.81  ? 278 PHE B CB  1 
ATOM   7966 C CG  . PHE D 4 296 ? 142.186 154.049 195.976 1.00 59.67  ? 278 PHE B CG  1 
ATOM   7967 C CD1 . PHE D 4 296 ? 140.815 154.151 196.109 1.00 61.54  ? 278 PHE B CD1 1 
ATOM   7968 C CD2 . PHE D 4 296 ? 142.783 152.826 196.205 1.00 60.67  ? 278 PHE B CD2 1 
ATOM   7969 C CE1 . PHE D 4 296 ? 140.052 153.047 196.433 1.00 55.72  ? 278 PHE B CE1 1 
ATOM   7970 C CE2 . PHE D 4 296 ? 142.023 151.723 196.533 1.00 62.02  ? 278 PHE B CE2 1 
ATOM   7971 C CZ  . PHE D 4 296 ? 140.657 151.836 196.648 1.00 55.57  ? 278 PHE B CZ  1 
ATOM   7972 N N   . SER D 4 297 ? 141.779 157.541 193.888 1.00 66.88  ? 279 SER B N   1 
ATOM   7973 C CA  . SER D 4 297 ? 141.521 158.970 193.817 1.00 63.63  ? 279 SER B CA  1 
ATOM   7974 C C   . SER D 4 297 ? 141.351 159.550 195.216 1.00 70.33  ? 279 SER B C   1 
ATOM   7975 O O   . SER D 4 297 ? 141.090 158.833 196.185 1.00 76.02  ? 279 SER B O   1 
ATOM   7976 C CB  . SER D 4 297 ? 140.274 159.256 192.984 1.00 61.64  ? 279 SER B CB  1 
ATOM   7977 O OG  . SER D 4 297 ? 139.633 160.437 193.432 1.00 58.88  ? 279 SER B OG  1 
ATOM   7978 N N   . LYS D 4 298 ? 141.511 160.868 195.312 1.00 71.63  ? 280 LYS B N   1 
ATOM   7979 C CA  . LYS D 4 298 ? 141.294 161.545 196.581 1.00 63.81  ? 280 LYS B CA  1 
ATOM   7980 C C   . LYS D 4 298 ? 139.841 161.385 197.006 1.00 64.78  ? 280 LYS B C   1 
ATOM   7981 O O   . LYS D 4 298 ? 138.932 161.376 196.172 1.00 72.02  ? 280 LYS B O   1 
ATOM   7982 C CB  . LYS D 4 298 ? 141.660 163.024 196.469 1.00 65.54  ? 280 LYS B CB  1 
ATOM   7983 C CG  . LYS D 4 298 ? 142.264 163.607 197.733 1.00 67.49  ? 280 LYS B CG  1 
ATOM   7984 C CD  . LYS D 4 298 ? 142.995 164.907 197.444 1.00 73.10  ? 280 LYS B CD  1 
ATOM   7985 C CE  . LYS D 4 298 ? 143.196 165.723 198.710 1.00 72.19  ? 280 LYS B CE  1 
ATOM   7986 N NZ  . LYS D 4 298 ? 141.951 166.424 199.122 1.00 67.85  ? 280 LYS B NZ  1 
ATOM   7987 N N   . SER D 4 299 ? 139.633 161.235 198.314 1.00 59.91  ? 281 SER B N   1 
ATOM   7988 C CA  . SER D 4 299 ? 138.373 160.878 198.960 1.00 64.52  ? 281 SER B CA  1 
ATOM   7989 C C   . SER D 4 299 ? 137.978 159.432 198.696 1.00 66.50  ? 281 SER B C   1 
ATOM   7990 O O   . SER D 4 299 ? 136.974 158.969 199.251 1.00 67.59  ? 281 SER B O   1 
ATOM   7991 C CB  . SER D 4 299 ? 137.209 161.794 198.552 1.00 72.22  ? 281 SER B CB  1 
ATOM   7992 O OG  . SER D 4 299 ? 136.799 161.537 197.221 1.00 75.40  ? 281 SER B OG  1 
ATOM   7993 N N   . GLY D 4 300 ? 138.731 158.702 197.880 1.00 73.95  ? 282 GLY B N   1 
ATOM   7994 C CA  . GLY D 4 300 ? 138.507 157.276 197.697 1.00 73.00  ? 282 GLY B CA  1 
ATOM   7995 C C   . GLY D 4 300 ? 137.161 156.899 197.118 1.00 72.61  ? 282 GLY B C   1 
ATOM   7996 O O   . GLY D 4 300 ? 136.556 155.914 197.558 1.00 78.24  ? 282 GLY B O   1 
ATOM   7997 N N   . ARG D 4 301 ? 136.677 157.656 196.136 1.00 61.55  ? 283 ARG B N   1 
ATOM   7998 C CA  . ARG D 4 301 ? 135.443 157.308 195.447 1.00 61.53  ? 283 ARG B CA  1 
ATOM   7999 C C   . ARG D 4 301 ? 135.690 156.621 194.112 1.00 64.47  ? 283 ARG B C   1 
ATOM   8000 O O   . ARG D 4 301 ? 134.782 155.964 193.591 1.00 73.31  ? 283 ARG B O   1 
ATOM   8001 C CB  . ARG D 4 301 ? 134.587 158.563 195.232 1.00 59.98  ? 283 ARG B CB  1 
ATOM   8002 C CG  . ARG D 4 301 ? 133.201 158.306 194.666 1.00 57.16  ? 283 ARG B CG  1 
ATOM   8003 C CD  . ARG D 4 301 ? 132.333 157.569 195.656 1.00 58.08  ? 283 ARG B CD  1 
ATOM   8004 N NE  . ARG D 4 301 ? 131.080 157.127 195.058 1.00 62.71  ? 283 ARG B NE  1 
ATOM   8005 C CZ  . ARG D 4 301 ? 129.885 157.585 195.403 1.00 68.25  ? 283 ARG B CZ  1 
ATOM   8006 N NH1 . ARG D 4 301 ? 129.744 158.509 196.337 1.00 67.15  ? 283 ARG B NH1 1 
ATOM   8007 N NH2 . ARG D 4 301 ? 128.806 157.103 194.794 1.00 69.94  ? 283 ARG B NH2 1 
ATOM   8008 N N   . LEU D 4 302 ? 136.895 156.732 193.567 1.00 56.06  ? 284 LEU B N   1 
ATOM   8009 C CA  . LEU D 4 302 ? 137.236 156.149 192.282 1.00 58.55  ? 284 LEU B CA  1 
ATOM   8010 C C   . LEU D 4 302 ? 138.460 155.257 192.421 1.00 69.82  ? 284 LEU B C   1 
ATOM   8011 O O   . LEU D 4 302 ? 139.295 155.451 193.309 1.00 77.48  ? 284 LEU B O   1 
ATOM   8012 C CB  . LEU D 4 302 ? 137.511 157.232 191.240 1.00 59.67  ? 284 LEU B CB  1 
ATOM   8013 C CG  . LEU D 4 302 ? 136.366 158.184 190.916 1.00 59.97  ? 284 LEU B CG  1 
ATOM   8014 C CD1 . LEU D 4 302 ? 136.789 159.110 189.803 1.00 57.35  ? 284 LEU B CD1 1 
ATOM   8015 C CD2 . LEU D 4 302 ? 135.123 157.413 190.528 1.00 63.17  ? 284 LEU B CD2 1 
ATOM   8016 N N   . LEU D 4 303 ? 138.556 154.272 191.531 1.00 69.59  ? 285 LEU B N   1 
ATOM   8017 C CA  . LEU D 4 303 ? 139.701 153.369 191.469 1.00 60.62  ? 285 LEU B CA  1 
ATOM   8018 C C   . LEU D 4 303 ? 140.159 153.302 190.020 1.00 55.34  ? 285 LEU B C   1 
ATOM   8019 O O   . LEU D 4 303 ? 139.408 152.843 189.153 1.00 64.93  ? 285 LEU B O   1 
ATOM   8020 C CB  . LEU D 4 303 ? 139.336 151.981 191.996 1.00 60.50  ? 285 LEU B CB  1 
ATOM   8021 C CG  . LEU D 4 303 ? 140.450 150.940 192.111 1.00 65.77  ? 285 LEU B CG  1 
ATOM   8022 C CD1 . LEU D 4 303 ? 141.689 151.552 192.721 1.00 65.80  ? 285 LEU B CD1 1 
ATOM   8023 C CD2 . LEU D 4 303 ? 139.991 149.759 192.936 1.00 60.75  ? 285 LEU B CD2 1 
ATOM   8024 N N   . LEU D 4 304 ? 141.371 153.774 189.748 1.00 60.11  ? 286 LEU B N   1 
ATOM   8025 C CA  . LEU D 4 304 ? 141.930 153.762 188.405 1.00 68.39  ? 286 LEU B CA  1 
ATOM   8026 C C   . LEU D 4 304 ? 142.800 152.522 188.249 1.00 75.80  ? 286 LEU B C   1 
ATOM   8027 O O   . LEU D 4 304 ? 143.727 152.304 189.039 1.00 86.31  ? 286 LEU B O   1 
ATOM   8028 C CB  . LEU D 4 304 ? 142.743 155.028 188.141 1.00 72.76  ? 286 LEU B CB  1 
ATOM   8029 C CG  . LEU D 4 304 ? 141.956 156.302 187.832 1.00 69.99  ? 286 LEU B CG  1 
ATOM   8030 C CD1 . LEU D 4 304 ? 141.848 157.182 189.064 1.00 69.09  ? 286 LEU B CD1 1 
ATOM   8031 C CD2 . LEU D 4 304 ? 142.602 157.060 186.686 1.00 73.89  ? 286 LEU B CD2 1 
ATOM   8032 N N   . ALA D 4 305 ? 142.504 151.713 187.234 1.00 66.60  ? 287 ALA B N   1 
ATOM   8033 C CA  . ALA D 4 305 ? 143.233 150.477 186.980 1.00 64.96  ? 287 ALA B CA  1 
ATOM   8034 C C   . ALA D 4 305 ? 143.720 150.468 185.540 1.00 67.33  ? 287 ALA B C   1 
ATOM   8035 O O   . ALA D 4 305 ? 142.920 150.611 184.610 1.00 78.89  ? 287 ALA B O   1 
ATOM   8036 C CB  . ALA D 4 305 ? 142.355 149.256 187.257 1.00 69.02  ? 287 ALA B CB  1 
ATOM   8037 N N   . GLY D 4 306 ? 145.023 150.291 185.356 1.00 66.16  ? 288 GLY B N   1 
ATOM   8038 C CA  . GLY D 4 306 ? 145.590 150.191 184.028 1.00 71.35  ? 288 GLY B CA  1 
ATOM   8039 C C   . GLY D 4 306 ? 145.647 148.758 183.545 1.00 70.98  ? 288 GLY B C   1 
ATOM   8040 O O   . GLY D 4 306 ? 146.317 147.919 184.153 1.00 78.83  ? 288 GLY B O   1 
ATOM   8041 N N   . TYR D 4 307 ? 144.951 148.466 182.454 1.00 64.93  ? 289 TYR B N   1 
ATOM   8042 C CA  . TYR D 4 307 ? 144.849 147.114 181.933 1.00 64.98  ? 289 TYR B CA  1 
ATOM   8043 C C   . TYR D 4 307 ? 145.859 146.889 180.815 1.00 72.13  ? 289 TYR B C   1 
ATOM   8044 O O   . TYR D 4 307 ? 146.491 147.819 180.310 1.00 75.91  ? 289 TYR B O   1 
ATOM   8045 C CB  . TYR D 4 307 ? 143.428 146.836 181.440 1.00 63.08  ? 289 TYR B CB  1 
ATOM   8046 C CG  . TYR D 4 307 ? 142.411 146.721 182.549 1.00 62.88  ? 289 TYR B CG  1 
ATOM   8047 C CD1 . TYR D 4 307 ? 141.928 147.846 183.195 1.00 66.96  ? 289 TYR B CD1 1 
ATOM   8048 C CD2 . TYR D 4 307 ? 141.933 145.484 182.950 1.00 67.80  ? 289 TYR B CD2 1 
ATOM   8049 C CE1 . TYR D 4 307 ? 141.001 147.742 184.210 1.00 69.64  ? 289 TYR B CE1 1 
ATOM   8050 C CE2 . TYR D 4 307 ? 141.006 145.370 183.962 1.00 70.96  ? 289 TYR B CE2 1 
ATOM   8051 C CZ  . TYR D 4 307 ? 140.542 146.501 184.589 1.00 73.16  ? 289 TYR B CZ  1 
ATOM   8052 O OH  . TYR D 4 307 ? 139.617 146.391 185.599 1.00 80.58  ? 289 TYR B OH  1 
ATOM   8053 N N   . ASP D 4 308 ? 146.006 145.622 180.433 1.00 75.88  ? 290 ASP B N   1 
ATOM   8054 C CA  . ASP D 4 308 ? 146.977 145.231 179.422 1.00 73.75  ? 290 ASP B CA  1 
ATOM   8055 C C   . ASP D 4 308 ? 146.465 145.405 177.999 1.00 77.20  ? 290 ASP B C   1 
ATOM   8056 O O   . ASP D 4 308 ? 147.262 145.304 177.060 1.00 79.93  ? 290 ASP B O   1 
ATOM   8057 C CB  . ASP D 4 308 ? 147.396 143.776 179.641 1.00 73.38  ? 290 ASP B CB  1 
ATOM   8058 C CG  . ASP D 4 308 ? 148.477 143.330 178.684 1.00 76.51  ? 290 ASP B CG  1 
ATOM   8059 O OD1 . ASP D 4 308 ? 148.917 144.156 177.861 1.00 75.82  ? 290 ASP B OD1 1 
ATOM   8060 O OD2 . ASP D 4 308 ? 148.888 142.153 178.755 1.00 81.24  ? 290 ASP B OD2 1 
ATOM   8061 N N   . ASP D 4 309 ? 145.172 145.657 177.811 1.00 78.31  ? 291 ASP B N   1 
ATOM   8062 C CA  . ASP D 4 309 ? 144.625 145.877 176.472 1.00 75.48  ? 291 ASP B CA  1 
ATOM   8063 C C   . ASP D 4 309 ? 144.608 147.359 176.107 1.00 75.97  ? 291 ASP B C   1 
ATOM   8064 O O   . ASP D 4 309 ? 143.604 147.902 175.648 1.00 77.98  ? 291 ASP B O   1 
ATOM   8065 C CB  . ASP D 4 309 ? 143.230 145.270 176.374 1.00 75.02  ? 291 ASP B CB  1 
ATOM   8066 C CG  . ASP D 4 309 ? 142.257 145.879 177.360 1.00 76.86  ? 291 ASP B CG  1 
ATOM   8067 O OD1 . ASP D 4 309 ? 142.710 146.556 178.304 1.00 78.36  ? 291 ASP B OD1 1 
ATOM   8068 O OD2 . ASP D 4 309 ? 141.037 145.682 177.191 1.00 79.11  ? 291 ASP B OD2 1 
ATOM   8069 N N   . PHE D 4 310 ? 145.748 148.016 176.309 1.00 70.40  ? 292 PHE B N   1 
ATOM   8070 C CA  . PHE D 4 310 ? 146.006 149.382 175.858 1.00 74.77  ? 292 PHE B CA  1 
ATOM   8071 C C   . PHE D 4 310 ? 144.999 150.394 176.401 1.00 78.42  ? 292 PHE B C   1 
ATOM   8072 O O   . PHE D 4 310 ? 144.766 151.432 175.774 1.00 81.29  ? 292 PHE B O   1 
ATOM   8073 C CB  . PHE D 4 310 ? 146.033 149.457 174.327 1.00 74.44  ? 292 PHE B CB  1 
ATOM   8074 C CG  . PHE D 4 310 ? 146.593 148.231 173.667 1.00 71.77  ? 292 PHE B CG  1 
ATOM   8075 C CD1 . PHE D 4 310 ? 147.874 147.798 173.945 1.00 71.26  ? 292 PHE B CD1 1 
ATOM   8076 C CD2 . PHE D 4 310 ? 145.838 147.521 172.751 1.00 75.93  ? 292 PHE B CD2 1 
ATOM   8077 C CE1 . PHE D 4 310 ? 148.391 146.675 173.334 1.00 77.26  ? 292 PHE B CE1 1 
ATOM   8078 C CE2 . PHE D 4 310 ? 146.349 146.396 172.134 1.00 78.00  ? 292 PHE B CE2 1 
ATOM   8079 C CZ  . PHE D 4 310 ? 147.628 145.973 172.427 1.00 79.25  ? 292 PHE B CZ  1 
ATOM   8080 N N   . ASN D 4 311 ? 144.391 150.131 177.551 1.00 74.59  ? 293 ASN B N   1 
ATOM   8081 C CA  . ASN D 4 311 ? 143.353 150.998 178.095 1.00 70.06  ? 293 ASN B CA  1 
ATOM   8082 C C   . ASN D 4 311 ? 143.678 151.384 179.535 1.00 77.66  ? 293 ASN B C   1 
ATOM   8083 O O   . ASN D 4 311 ? 144.725 151.029 180.082 1.00 88.36  ? 293 ASN B O   1 
ATOM   8084 C CB  . ASN D 4 311 ? 141.984 150.319 178.021 1.00 75.20  ? 293 ASN B CB  1 
ATOM   8085 C CG  . ASN D 4 311 ? 141.236 150.655 176.752 1.00 76.28  ? 293 ASN B CG  1 
ATOM   8086 O OD1 . ASN D 4 311 ? 141.785 151.266 175.837 1.00 74.68  ? 293 ASN B OD1 1 
ATOM   8087 N ND2 . ASN D 4 311 ? 139.969 150.265 176.693 1.00 77.69  ? 293 ASN B ND2 1 
ATOM   8088 N N   . CYS D 4 312 ? 142.751 152.120 180.145 1.00 75.83  ? 294 CYS B N   1 
ATOM   8089 C CA  . CYS D 4 312 ? 142.857 152.503 181.552 1.00 72.71  ? 294 CYS B CA  1 
ATOM   8090 C C   . CYS D 4 312 ? 141.445 152.778 182.047 1.00 69.60  ? 294 CYS B C   1 
ATOM   8091 O O   . CYS D 4 312 ? 140.804 153.728 181.588 1.00 79.74  ? 294 CYS B O   1 
ATOM   8092 C CB  . CYS D 4 312 ? 143.755 153.721 181.724 1.00 73.82  ? 294 CYS B CB  1 
ATOM   8093 S SG  . CYS D 4 312 ? 143.530 154.591 183.289 1.00 88.90  ? 294 CYS B SG  1 
ATOM   8094 N N   . ASN D 4 313 ? 140.965 151.954 182.970 1.00 61.12  ? 295 ASN B N   1 
ATOM   8095 C CA  . ASN D 4 313 ? 139.572 151.957 183.380 1.00 63.99  ? 295 ASN B CA  1 
ATOM   8096 C C   . ASN D 4 313 ? 139.403 152.648 184.728 1.00 71.45  ? 295 ASN B C   1 
ATOM   8097 O O   . ASN D 4 313 ? 140.327 152.713 185.545 1.00 80.30  ? 295 ASN B O   1 
ATOM   8098 C CB  . ASN D 4 313 ? 139.042 150.525 183.459 1.00 70.35  ? 295 ASN B CB  1 
ATOM   8099 C CG  . ASN D 4 313 ? 138.382 150.079 182.176 1.00 77.17  ? 295 ASN B CG  1 
ATOM   8100 O OD1 . ASN D 4 313 ? 137.297 149.506 182.190 1.00 80.77  ? 295 ASN B OD1 1 
ATOM   8101 N ND2 . ASN D 4 313 ? 139.041 150.336 181.054 1.00 75.11  ? 295 ASN B ND2 1 
ATOM   8102 N N   . VAL D 4 314 ? 138.194 153.157 184.953 1.00 64.51  ? 296 VAL B N   1 
ATOM   8103 C CA  . VAL D 4 314 ? 137.845 153.871 186.175 1.00 66.15  ? 296 VAL B CA  1 
ATOM   8104 C C   . VAL D 4 314 ? 136.617 153.198 186.771 1.00 66.40  ? 296 VAL B C   1 
ATOM   8105 O O   . VAL D 4 314 ? 135.573 153.111 186.114 1.00 69.79  ? 296 VAL B O   1 
ATOM   8106 C CB  . VAL D 4 314 ? 137.576 155.362 185.912 1.00 69.56  ? 296 VAL B CB  1 
ATOM   8107 C CG1 . VAL D 4 314 ? 136.651 155.938 186.975 1.00 71.87  ? 296 VAL B CG1 1 
ATOM   8108 C CG2 . VAL D 4 314 ? 138.880 156.133 185.858 1.00 73.93  ? 296 VAL B CG2 1 
ATOM   8109 N N   . TRP D 4 315 ? 136.743 152.717 188.004 1.00 66.44  ? 297 TRP B N   1 
ATOM   8110 C CA  . TRP D 4 315 ? 135.668 152.027 188.698 1.00 60.95  ? 297 TRP B CA  1 
ATOM   8111 C C   . TRP D 4 315 ? 135.178 152.864 189.871 1.00 59.73  ? 297 TRP B C   1 
ATOM   8112 O O   . TRP D 4 315 ? 135.932 153.644 190.457 1.00 70.06  ? 297 TRP B O   1 
ATOM   8113 C CB  . TRP D 4 315 ? 136.125 150.658 189.216 1.00 64.81  ? 297 TRP B CB  1 
ATOM   8114 C CG  . TRP D 4 315 ? 136.662 149.733 188.168 1.00 67.56  ? 297 TRP B CG  1 
ATOM   8115 C CD1 . TRP D 4 315 ? 137.919 149.729 187.644 1.00 67.19  ? 297 TRP B CD1 1 
ATOM   8116 C CD2 . TRP D 4 315 ? 135.962 148.658 187.536 1.00 64.70  ? 297 TRP B CD2 1 
ATOM   8117 N NE1 . TRP D 4 315 ? 138.043 148.726 186.716 1.00 61.98  ? 297 TRP B NE1 1 
ATOM   8118 C CE2 . TRP D 4 315 ? 136.853 148.054 186.631 1.00 61.64  ? 297 TRP B CE2 1 
ATOM   8119 C CE3 . TRP D 4 315 ? 134.664 148.152 187.642 1.00 67.66  ? 297 TRP B CE3 1 
ATOM   8120 C CZ2 . TRP D 4 315 ? 136.490 146.973 185.838 1.00 65.76  ? 297 TRP B CZ2 1 
ATOM   8121 C CZ3 . TRP D 4 315 ? 134.306 147.080 186.855 1.00 68.89  ? 297 TRP B CZ3 1 
ATOM   8122 C CH2 . TRP D 4 315 ? 135.215 146.500 185.965 1.00 69.12  ? 297 TRP B CH2 1 
ATOM   8123 N N   . ASP D 4 316 ? 133.909 152.681 190.216 1.00 50.01  ? 298 ASP B N   1 
ATOM   8124 C CA  . ASP D 4 316 ? 133.326 153.297 191.399 1.00 48.91  ? 298 ASP B CA  1 
ATOM   8125 C C   . ASP D 4 316 ? 133.688 152.440 192.606 1.00 54.93  ? 298 ASP B C   1 
ATOM   8126 O O   . ASP D 4 316 ? 133.411 151.237 192.623 1.00 64.08  ? 298 ASP B O   1 
ATOM   8127 C CB  . ASP D 4 316 ? 131.812 153.428 191.240 1.00 55.11  ? 298 ASP B CB  1 
ATOM   8128 C CG  . ASP D 4 316 ? 131.167 154.238 192.349 1.00 66.24  ? 298 ASP B CG  1 
ATOM   8129 O OD1 . ASP D 4 316 ? 131.413 153.951 193.539 1.00 70.06  ? 298 ASP B OD1 1 
ATOM   8130 O OD2 . ASP D 4 316 ? 130.397 155.165 192.026 1.00 73.24  ? 298 ASP B OD2 1 
ATOM   8131 N N   . ALA D 4 317 ? 134.311 153.057 193.609 1.00 61.35  ? 299 ALA B N   1 
ATOM   8132 C CA  . ALA D 4 317 ? 134.870 152.294 194.719 1.00 59.22  ? 299 ALA B CA  1 
ATOM   8133 C C   . ALA D 4 317 ? 133.807 151.730 195.649 1.00 56.69  ? 299 ALA B C   1 
ATOM   8134 O O   . ALA D 4 317 ? 134.078 150.750 196.349 1.00 70.11  ? 299 ALA B O   1 
ATOM   8135 C CB  . ALA D 4 317 ? 135.841 153.164 195.517 1.00 61.91  ? 299 ALA B CB  1 
ATOM   8136 N N   . LEU D 4 318 ? 132.612 152.315 195.679 1.00 62.45  ? 300 LEU B N   1 
ATOM   8137 C CA  . LEU D 4 318 ? 131.570 151.860 196.589 1.00 71.64  ? 300 LEU B CA  1 
ATOM   8138 C C   . LEU D 4 318 ? 130.611 150.861 195.960 1.00 75.68  ? 300 LEU B C   1 
ATOM   8139 O O   . LEU D 4 318 ? 130.044 150.031 196.678 1.00 77.49  ? 300 LEU B O   1 
ATOM   8140 C CB  . LEU D 4 318 ? 130.773 153.054 197.126 1.00 71.79  ? 300 LEU B CB  1 
ATOM   8141 C CG  . LEU D 4 318 ? 131.401 153.825 198.290 1.00 72.41  ? 300 LEU B CG  1 
ATOM   8142 C CD1 . LEU D 4 318 ? 130.324 154.486 199.131 1.00 73.68  ? 300 LEU B CD1 1 
ATOM   8143 C CD2 . LEU D 4 318 ? 132.267 152.914 199.145 1.00 72.68  ? 300 LEU B CD2 1 
ATOM   8144 N N   . LYS D 4 319 ? 130.412 150.919 194.647 1.00 74.49  ? 301 LYS B N   1 
ATOM   8145 C CA  . LYS D 4 319 ? 129.613 149.931 193.938 1.00 74.66  ? 301 LYS B CA  1 
ATOM   8146 C C   . LYS D 4 319 ? 130.305 149.584 192.629 1.00 73.51  ? 301 LYS B C   1 
ATOM   8147 O O   . LYS D 4 319 ? 130.856 150.460 191.958 1.00 81.11  ? 301 LYS B O   1 
ATOM   8148 C CB  . LYS D 4 319 ? 128.183 150.430 193.692 1.00 70.09  ? 301 LYS B CB  1 
ATOM   8149 C CG  . LYS D 4 319 ? 128.080 151.715 192.896 1.00 70.16  ? 301 LYS B CG  1 
ATOM   8150 C CD  . LYS D 4 319 ? 126.635 152.013 192.533 1.00 71.34  ? 301 LYS B CD  1 
ATOM   8151 C CE  . LYS D 4 319 ? 125.748 152.042 193.757 1.00 67.60  ? 301 LYS B CE  1 
ATOM   8152 N NZ  . LYS D 4 319 ? 126.361 152.849 194.832 1.00 70.49  ? 301 LYS B NZ  1 
ATOM   8153 N N   . ALA D 4 320 ? 130.267 148.309 192.272 1.00 69.12  ? 302 ALA B N   1 
ATOM   8154 C CA  . ALA D 4 320 ? 131.116 147.739 191.228 1.00 70.92  ? 302 ALA B CA  1 
ATOM   8155 C C   . ALA D 4 320 ? 130.760 148.186 189.816 1.00 77.08  ? 302 ALA B C   1 
ATOM   8156 O O   . ALA D 4 320 ? 131.372 147.613 188.903 1.00 84.19  ? 302 ALA B O   1 
ATOM   8157 C CB  . ALA D 4 320 ? 131.073 146.213 191.308 1.00 74.86  ? 302 ALA B CB  1 
ATOM   8158 N N   . ASP D 4 321 ? 129.855 149.120 189.535 1.00 72.11  ? 303 ASP B N   1 
ATOM   8159 C CA  . ASP D 4 321 ? 129.646 149.522 188.153 1.00 71.29  ? 303 ASP B CA  1 
ATOM   8160 C C   . ASP D 4 321 ? 130.868 150.272 187.629 1.00 66.48  ? 303 ASP B C   1 
ATOM   8161 O O   . ASP D 4 321 ? 131.704 150.766 188.389 1.00 71.45  ? 303 ASP B O   1 
ATOM   8162 C CB  . ASP D 4 321 ? 128.397 150.390 188.013 1.00 73.87  ? 303 ASP B CB  1 
ATOM   8163 C CG  . ASP D 4 321 ? 128.184 151.306 189.196 1.00 81.36  ? 303 ASP B CG  1 
ATOM   8164 O OD1 . ASP D 4 321 ? 129.180 151.681 189.849 1.00 82.76  ? 303 ASP B OD1 1 
ATOM   8165 O OD2 . ASP D 4 321 ? 127.018 151.660 189.461 1.00 83.56  ? 303 ASP B OD2 1 
ATOM   8166 N N   . ARG D 4 322 ? 130.972 150.286 186.302 1.00 63.68  ? 304 ARG B N   1 
ATOM   8167 C CA  . ARG D 4 322 ? 132.159 150.896 185.662 1.00 70.97  ? 304 ARG B CA  1 
ATOM   8168 C C   . ARG D 4 322 ? 131.859 152.295 185.142 1.00 79.09  ? 304 ARG B C   1 
ATOM   8169 O O   . ARG D 4 322 ? 130.837 152.471 184.458 1.00 81.27  ? 304 ARG B O   1 
ATOM   8170 C CB  . ARG D 4 322 ? 132.643 150.051 184.483 1.00 71.62  ? 304 ARG B CB  1 
ATOM   8171 C CG  . ARG D 4 322 ? 134.110 150.266 184.145 1.00 72.46  ? 304 ARG B CG  1 
ATOM   8172 C CD  . ARG D 4 322 ? 134.716 148.983 183.620 1.00 73.33  ? 304 ARG B CD  1 
ATOM   8173 N NE  . ARG D 4 322 ? 134.144 148.616 182.335 1.00 77.61  ? 304 ARG B NE  1 
ATOM   8174 C CZ  . ARG D 4 322 ? 134.430 149.219 181.188 1.00 77.86  ? 304 ARG B CZ  1 
ATOM   8175 N NH1 . ARG D 4 322 ? 135.290 148.669 180.351 1.00 73.66  ? 304 ARG B NH1 1 
ATOM   8176 N NH2 . ARG D 4 322 ? 133.855 150.369 180.884 1.00 79.56  ? 304 ARG B NH2 1 
ATOM   8177 N N   . ALA D 4 323 ? 132.732 153.235 185.458 1.00 78.65  ? 305 ALA B N   1 
ATOM   8178 C CA  . ALA D 4 323 ? 132.643 154.612 184.995 1.00 71.91  ? 305 ALA B CA  1 
ATOM   8179 C C   . ALA D 4 323 ? 133.437 154.750 183.695 1.00 75.60  ? 305 ALA B C   1 
ATOM   8180 O O   . ALA D 4 323 ? 133.797 153.752 183.067 1.00 78.59  ? 305 ALA B O   1 
ATOM   8181 C CB  . ALA D 4 323 ? 133.123 155.564 186.093 1.00 71.77  ? 305 ALA B CB  1 
ATOM   8182 N N   . GLY D 4 324 ? 133.705 155.983 183.271 1.00 81.57  ? 306 GLY B N   1 
ATOM   8183 C CA  . GLY D 4 324 ? 134.369 156.248 182.008 1.00 82.64  ? 306 GLY B CA  1 
ATOM   8184 C C   . GLY D 4 324 ? 135.676 155.518 181.774 1.00 81.08  ? 306 GLY B C   1 
ATOM   8185 O O   . GLY D 4 324 ? 136.308 155.027 182.714 1.00 81.32  ? 306 GLY B O   1 
ATOM   8186 N N   . VAL D 4 325 ? 136.092 155.450 180.513 1.00 63.93  ? 307 VAL B N   1 
ATOM   8187 C CA  . VAL D 4 325 ? 137.285 154.724 180.098 1.00 58.74  ? 307 VAL B CA  1 
ATOM   8188 C C   . VAL D 4 325 ? 138.281 155.721 179.527 1.00 60.57  ? 307 VAL B C   1 
ATOM   8189 O O   . VAL D 4 325 ? 137.913 156.577 178.715 1.00 71.03  ? 307 VAL B O   1 
ATOM   8190 C CB  . VAL D 4 325 ? 136.952 153.636 179.061 1.00 68.16  ? 307 VAL B CB  1 
ATOM   8191 C CG1 . VAL D 4 325 ? 138.172 152.777 178.782 1.00 69.59  ? 307 VAL B CG1 1 
ATOM   8192 C CG2 . VAL D 4 325 ? 135.790 152.784 179.543 1.00 69.91  ? 307 VAL B CG2 1 
ATOM   8193 N N   . LEU D 4 326 ? 139.537 155.609 179.953 1.00 54.76  ? 308 LEU B N   1 
ATOM   8194 C CA  . LEU D 4 326 ? 140.606 156.491 179.491 1.00 56.28  ? 308 LEU B CA  1 
ATOM   8195 C C   . LEU D 4 326 ? 141.404 155.746 178.425 1.00 64.18  ? 308 LEU B C   1 
ATOM   8196 O O   . LEU D 4 326 ? 142.425 155.115 178.696 1.00 74.01  ? 308 LEU B O   1 
ATOM   8197 C CB  . LEU D 4 326 ? 141.487 156.924 180.657 1.00 64.35  ? 308 LEU B CB  1 
ATOM   8198 C CG  . LEU D 4 326 ? 141.093 158.181 181.430 1.00 63.45  ? 308 LEU B CG  1 
ATOM   8199 C CD1 . LEU D 4 326 ? 139.775 157.978 182.148 1.00 64.57  ? 308 LEU B CD1 1 
ATOM   8200 C CD2 . LEU D 4 326 ? 142.184 158.556 182.415 1.00 63.75  ? 308 LEU B CD2 1 
ATOM   8201 N N   . ALA D 4 327 ? 140.924 155.829 177.189 1.00 61.84  ? 309 ALA B N   1 
ATOM   8202 C CA  . ALA D 4 327 ? 141.516 155.114 176.061 1.00 67.42  ? 309 ALA B CA  1 
ATOM   8203 C C   . ALA D 4 327 ? 142.204 156.122 175.147 1.00 64.12  ? 309 ALA B C   1 
ATOM   8204 O O   . ALA D 4 327 ? 141.550 156.795 174.347 1.00 66.52  ? 309 ALA B O   1 
ATOM   8205 C CB  . ALA D 4 327 ? 140.456 154.316 175.309 1.00 68.66  ? 309 ALA B CB  1 
ATOM   8206 N N   . GLY D 4 328 ? 143.524 156.224 175.271 1.00 57.02  ? 310 GLY B N   1 
ATOM   8207 C CA  . GLY D 4 328 ? 144.295 157.090 174.404 1.00 59.02  ? 310 GLY B CA  1 
ATOM   8208 C C   . GLY D 4 328 ? 145.669 156.548 174.072 1.00 61.89  ? 310 GLY B C   1 
ATOM   8209 O O   . GLY D 4 328 ? 146.495 157.257 173.490 1.00 69.22  ? 310 GLY B O   1 
ATOM   8210 N N   . HIS D 4 329 ? 145.928 155.295 174.430 1.00 59.30  ? 311 HIS B N   1 
ATOM   8211 C CA  . HIS D 4 329 ? 147.255 154.710 174.331 1.00 63.90  ? 311 HIS B CA  1 
ATOM   8212 C C   . HIS D 4 329 ? 147.302 153.647 173.242 1.00 63.63  ? 311 HIS B C   1 
ATOM   8213 O O   . HIS D 4 329 ? 146.319 152.945 172.990 1.00 65.47  ? 311 HIS B O   1 
ATOM   8214 C CB  . HIS D 4 329 ? 147.680 154.097 175.668 1.00 64.53  ? 311 HIS B CB  1 
ATOM   8215 C CG  . HIS D 4 329 ? 148.275 155.084 176.620 1.00 64.32  ? 311 HIS B CG  1 
ATOM   8216 N ND1 . HIS D 4 329 ? 149.528 155.628 176.440 1.00 64.26  ? 311 HIS B ND1 1 
ATOM   8217 C CD2 . HIS D 4 329 ? 147.790 155.627 177.761 1.00 67.07  ? 311 HIS B CD2 1 
ATOM   8218 C CE1 . HIS D 4 329 ? 149.789 156.464 177.429 1.00 64.42  ? 311 HIS B CE1 1 
ATOM   8219 N NE2 . HIS D 4 329 ? 148.750 156.482 178.243 1.00 67.84  ? 311 HIS B NE2 1 
ATOM   8220 N N   . ASP D 4 330 ? 148.462 153.538 172.596 1.00 79.91  ? 312 ASP B N   1 
ATOM   8221 C CA  . ASP D 4 330 ? 148.690 152.556 171.546 1.00 78.73  ? 312 ASP B CA  1 
ATOM   8222 C C   . ASP D 4 330 ? 149.414 151.310 172.040 1.00 81.02  ? 312 ASP B C   1 
ATOM   8223 O O   . ASP D 4 330 ? 149.679 150.409 171.239 1.00 83.57  ? 312 ASP B O   1 
ATOM   8224 C CB  . ASP D 4 330 ? 149.482 153.187 170.397 1.00 85.61  ? 312 ASP B CB  1 
ATOM   8225 N N   . ASN D 4 331 ? 149.741 151.236 173.327 1.00 78.47  ? 313 ASN B N   1 
ATOM   8226 C CA  . ASN D 4 331 ? 150.355 150.045 173.898 1.00 74.50  ? 313 ASN B CA  1 
ATOM   8227 C C   . ASN D 4 331 ? 149.904 149.916 175.348 1.00 79.31  ? 313 ASN B C   1 
ATOM   8228 O O   . ASN D 4 331 ? 149.127 150.731 175.853 1.00 83.44  ? 313 ASN B O   1 
ATOM   8229 C CB  . ASN D 4 331 ? 151.879 150.086 173.776 1.00 76.54  ? 313 ASN B CB  1 
ATOM   8230 C CG  . ASN D 4 331 ? 152.478 148.712 173.558 1.00 81.04  ? 313 ASN B CG  1 
ATOM   8231 O OD1 . ASN D 4 331 ? 152.201 147.778 174.308 1.00 81.95  ? 313 ASN B OD1 1 
ATOM   8232 N ND2 . ASN D 4 331 ? 153.300 148.581 172.525 1.00 82.57  ? 313 ASN B ND2 1 
ATOM   8233 N N   . ARG D 4 332 ? 150.395 148.876 176.017 1.00 73.26  ? 314 ARG B N   1 
ATOM   8234 C CA  . ARG D 4 332 ? 149.914 148.548 177.353 1.00 71.27  ? 314 ARG B CA  1 
ATOM   8235 C C   . ARG D 4 332 ? 150.328 149.605 178.367 1.00 70.23  ? 314 ARG B C   1 
ATOM   8236 O O   . ARG D 4 332 ? 151.461 150.093 178.354 1.00 77.29  ? 314 ARG B O   1 
ATOM   8237 C CB  . ARG D 4 332 ? 150.444 147.186 177.793 1.00 73.90  ? 314 ARG B CB  1 
ATOM   8238 C CG  . ARG D 4 332 ? 150.359 146.936 179.286 1.00 75.37  ? 314 ARG B CG  1 
ATOM   8239 C CD  . ARG D 4 332 ? 150.949 145.584 179.647 1.00 72.65  ? 314 ARG B CD  1 
ATOM   8240 N NE  . ARG D 4 332 ? 152.381 145.528 179.374 1.00 69.38  ? 314 ARG B NE  1 
ATOM   8241 C CZ  . ARG D 4 332 ? 153.079 144.406 179.265 1.00 72.28  ? 314 ARG B CZ  1 
ATOM   8242 N NH1 . ARG D 4 332 ? 153.485 143.738 180.332 1.00 74.54  ? 314 ARG B NH1 1 
ATOM   8243 N NH2 . ARG D 4 332 ? 153.382 143.946 178.055 1.00 73.69  ? 314 ARG B NH2 1 
ATOM   8244 N N   . VAL D 4 333 ? 149.402 149.943 179.262 1.00 56.63  ? 315 VAL B N   1 
ATOM   8245 C CA  . VAL D 4 333 ? 149.689 150.898 180.324 1.00 55.77  ? 315 VAL B CA  1 
ATOM   8246 C C   . VAL D 4 333 ? 150.557 150.227 181.378 1.00 66.54  ? 315 VAL B C   1 
ATOM   8247 O O   . VAL D 4 333 ? 150.222 149.151 181.889 1.00 72.64  ? 315 VAL B O   1 
ATOM   8248 C CB  . VAL D 4 333 ? 148.385 151.433 180.931 1.00 51.13  ? 315 VAL B CB  1 
ATOM   8249 C CG1 . VAL D 4 333 ? 148.658 152.130 182.248 1.00 59.04  ? 315 VAL B CG1 1 
ATOM   8250 C CG2 . VAL D 4 333 ? 147.703 152.379 179.962 1.00 64.35  ? 315 VAL B CG2 1 
ATOM   8251 N N   . SER D 4 334 ? 151.682 150.862 181.711 1.00 68.09  ? 316 SER B N   1 
ATOM   8252 C CA  . SER D 4 334 ? 152.627 150.294 182.659 1.00 60.52  ? 316 SER B CA  1 
ATOM   8253 C C   . SER D 4 334 ? 152.647 150.992 184.010 1.00 62.83  ? 316 SER B C   1 
ATOM   8254 O O   . SER D 4 334 ? 153.073 150.377 184.991 1.00 70.19  ? 316 SER B O   1 
ATOM   8255 C CB  . SER D 4 334 ? 154.046 150.311 182.075 1.00 62.60  ? 316 SER B CB  1 
ATOM   8256 O OG  . SER D 4 334 ? 154.383 151.599 181.593 1.00 69.22  ? 316 SER B OG  1 
ATOM   8257 N N   . CYS D 4 335 ? 152.203 152.244 184.093 1.00 64.66  ? 317 CYS B N   1 
ATOM   8258 C CA  . CYS D 4 335 ? 152.164 152.938 185.372 1.00 63.30  ? 317 CYS B CA  1 
ATOM   8259 C C   . CYS D 4 335 ? 151.102 154.024 185.326 1.00 67.60  ? 317 CYS B C   1 
ATOM   8260 O O   . CYS D 4 335 ? 150.777 154.545 184.258 1.00 78.21  ? 317 CYS B O   1 
ATOM   8261 C CB  . CYS D 4 335 ? 153.527 153.545 185.719 1.00 69.80  ? 317 CYS B CB  1 
ATOM   8262 S SG  . CYS D 4 335 ? 154.372 154.319 184.325 1.00 85.83  ? 317 CYS B SG  1 
ATOM   8263 N N   . LEU D 4 336 ? 150.562 154.363 186.494 1.00 60.84  ? 318 LEU B N   1 
ATOM   8264 C CA  . LEU D 4 336 ? 149.613 155.463 186.574 1.00 60.80  ? 318 LEU B CA  1 
ATOM   8265 C C   . LEU D 4 336 ? 149.573 155.973 188.007 1.00 69.47  ? 318 LEU B C   1 
ATOM   8266 O O   . LEU D 4 336 ? 149.721 155.202 188.958 1.00 78.31  ? 318 LEU B O   1 
ATOM   8267 C CB  . LEU D 4 336 ? 148.220 155.037 186.079 1.00 61.57  ? 318 LEU B CB  1 
ATOM   8268 C CG  . LEU D 4 336 ? 147.184 154.282 186.913 1.00 61.15  ? 318 LEU B CG  1 
ATOM   8269 C CD1 . LEU D 4 336 ? 146.439 155.195 187.873 1.00 58.53  ? 318 LEU B CD1 1 
ATOM   8270 C CD2 . LEU D 4 336 ? 146.208 153.550 186.006 1.00 63.28  ? 318 LEU B CD2 1 
ATOM   8271 N N   . GLY D 4 337 ? 149.366 157.280 188.146 1.00 72.61  ? 319 GLY B N   1 
ATOM   8272 C CA  . GLY D 4 337 ? 149.394 157.915 189.450 1.00 67.53  ? 319 GLY B CA  1 
ATOM   8273 C C   . GLY D 4 337 ? 148.440 159.087 189.535 1.00 66.37  ? 319 GLY B C   1 
ATOM   8274 O O   . GLY D 4 337 ? 148.022 159.658 188.522 1.00 76.73  ? 319 GLY B O   1 
ATOM   8275 N N   . VAL D 4 338 ? 148.103 159.441 190.775 1.00 60.27  ? 320 VAL B N   1 
ATOM   8276 C CA  . VAL D 4 338 ? 147.186 160.531 191.087 1.00 59.51  ? 320 VAL B CA  1 
ATOM   8277 C C   . VAL D 4 338 ? 147.893 161.498 192.027 1.00 67.23  ? 320 VAL B C   1 
ATOM   8278 O O   . VAL D 4 338 ? 148.554 161.074 192.982 1.00 69.95  ? 320 VAL B O   1 
ATOM   8279 C CB  . VAL D 4 338 ? 145.880 160.012 191.724 1.00 58.80  ? 320 VAL B CB  1 
ATOM   8280 C CG1 . VAL D 4 338 ? 144.970 161.166 192.092 1.00 55.99  ? 320 VAL B CG1 1 
ATOM   8281 C CG2 . VAL D 4 338 ? 145.175 159.053 190.789 1.00 62.19  ? 320 VAL B CG2 1 
ATOM   8282 N N   . THR D 4 339 ? 147.756 162.794 191.756 1.00 70.68  ? 321 THR B N   1 
ATOM   8283 C CA  . THR D 4 339 ? 148.449 163.801 192.544 1.00 68.28  ? 321 THR B CA  1 
ATOM   8284 C C   . THR D 4 339 ? 147.887 163.857 193.962 1.00 77.04  ? 321 THR B C   1 
ATOM   8285 O O   . THR D 4 339 ? 146.812 163.329 194.262 1.00 82.54  ? 321 THR B O   1 
ATOM   8286 C CB  . THR D 4 339 ? 148.338 165.175 191.888 1.00 68.18  ? 321 THR B CB  1 
ATOM   8287 O OG1 . THR D 4 339 ? 146.985 165.638 191.975 1.00 80.75  ? 321 THR B OG1 1 
ATOM   8288 C CG2 . THR D 4 339 ? 148.744 165.104 190.434 1.00 69.29  ? 321 THR B CG2 1 
ATOM   8289 N N   . ASP D 4 340 ? 148.637 164.518 194.847 1.00 81.75  ? 322 ASP B N   1 
ATOM   8290 C CA  . ASP D 4 340 ? 148.220 164.612 196.241 1.00 84.30  ? 322 ASP B CA  1 
ATOM   8291 C C   . ASP D 4 340 ? 147.031 165.548 196.414 1.00 82.29  ? 322 ASP B C   1 
ATOM   8292 O O   . ASP D 4 340 ? 146.251 165.385 197.359 1.00 84.13  ? 322 ASP B O   1 
ATOM   8293 C CB  . ASP D 4 340 ? 149.389 165.070 197.109 1.00 82.89  ? 322 ASP B CB  1 
ATOM   8294 C CG  . ASP D 4 340 ? 150.452 164.002 197.260 1.00 86.11  ? 322 ASP B CG  1 
ATOM   8295 O OD1 . ASP D 4 340 ? 150.166 162.829 196.942 1.00 87.37  ? 322 ASP B OD1 1 
ATOM   8296 O OD2 . ASP D 4 340 ? 151.573 164.335 197.699 1.00 85.59  ? 322 ASP B OD2 1 
ATOM   8297 N N   . ASP D 4 341 ? 146.874 166.525 195.526 1.00 78.65  ? 323 ASP B N   1 
ATOM   8298 C CA  . ASP D 4 341 ? 145.738 167.434 195.577 1.00 80.58  ? 323 ASP B CA  1 
ATOM   8299 C C   . ASP D 4 341 ? 144.565 166.963 194.728 1.00 86.27  ? 323 ASP B C   1 
ATOM   8300 O O   . ASP D 4 341 ? 143.539 167.649 194.680 1.00 92.22  ? 323 ASP B O   1 
ATOM   8301 C CB  . ASP D 4 341 ? 146.164 168.840 195.140 1.00 82.78  ? 323 ASP B CB  1 
ATOM   8302 C CG  . ASP D 4 341 ? 146.679 168.879 193.718 1.00 84.74  ? 323 ASP B CG  1 
ATOM   8303 O OD1 . ASP D 4 341 ? 147.051 167.812 193.189 1.00 88.93  ? 323 ASP B OD1 1 
ATOM   8304 O OD2 . ASP D 4 341 ? 146.713 169.978 193.127 1.00 83.03  ? 323 ASP B OD2 1 
ATOM   8305 N N   . GLY D 4 342 ? 144.689 165.818 194.062 1.00 79.67  ? 324 GLY B N   1 
ATOM   8306 C CA  . GLY D 4 342 ? 143.568 165.247 193.342 1.00 76.49  ? 324 GLY B CA  1 
ATOM   8307 C C   . GLY D 4 342 ? 143.178 165.966 192.074 1.00 77.73  ? 324 GLY B C   1 
ATOM   8308 O O   . GLY D 4 342 ? 142.030 165.851 191.640 1.00 82.61  ? 324 GLY B O   1 
ATOM   8309 N N   . MET D 4 343 ? 144.100 166.701 191.455 1.00 75.36  ? 325 MET B N   1 
ATOM   8310 C CA  . MET D 4 343 ? 143.754 167.472 190.267 1.00 76.25  ? 325 MET B CA  1 
ATOM   8311 C C   . MET D 4 343 ? 143.703 166.594 189.020 1.00 75.05  ? 325 MET B C   1 
ATOM   8312 O O   . MET D 4 343 ? 142.655 166.475 188.376 1.00 80.90  ? 325 MET B O   1 
ATOM   8313 C CB  . MET D 4 343 ? 144.750 168.617 190.078 1.00 85.06  ? 325 MET B CB  1 
ATOM   8314 C CG  . MET D 4 343 ? 144.141 169.865 189.465 1.00 90.02  ? 325 MET B CG  1 
ATOM   8315 S SD  . MET D 4 343 ? 142.503 170.226 190.125 1.00 101.62 ? 325 MET B SD  1 
ATOM   8316 C CE  . MET D 4 343 ? 142.925 171.213 191.558 1.00 83.10  ? 325 MET B CE  1 
ATOM   8317 N N   . ALA D 4 344 ? 144.823 165.971 188.664 1.00 59.64  ? 326 ALA B N   1 
ATOM   8318 C CA  . ALA D 4 344 ? 144.931 165.231 187.416 1.00 65.92  ? 326 ALA B CA  1 
ATOM   8319 C C   . ALA D 4 344 ? 145.530 163.855 187.667 1.00 66.47  ? 326 ALA B C   1 
ATOM   8320 O O   . ALA D 4 344 ? 146.145 163.602 188.705 1.00 70.80  ? 326 ALA B O   1 
ATOM   8321 C CB  . ALA D 4 344 ? 145.781 165.986 186.387 1.00 68.92  ? 326 ALA B CB  1 
ATOM   8322 N N   . VAL D 4 345 ? 145.342 162.963 186.696 1.00 66.93  ? 327 VAL B N   1 
ATOM   8323 C CA  . VAL D 4 345 ? 145.878 161.607 186.755 1.00 61.72  ? 327 VAL B CA  1 
ATOM   8324 C C   . VAL D 4 345 ? 146.836 161.416 185.586 1.00 56.86  ? 327 VAL B C   1 
ATOM   8325 O O   . VAL D 4 345 ? 146.518 161.774 184.448 1.00 72.05  ? 327 VAL B O   1 
ATOM   8326 C CB  . VAL D 4 345 ? 144.759 160.547 186.748 1.00 62.17  ? 327 VAL B CB  1 
ATOM   8327 C CG1 . VAL D 4 345 ? 143.833 160.762 187.929 1.00 69.63  ? 327 VAL B CG1 1 
ATOM   8328 C CG2 . VAL D 4 345 ? 143.959 160.591 185.458 1.00 61.93  ? 327 VAL B CG2 1 
ATOM   8329 N N   . ALA D 4 346 ? 148.016 160.876 185.865 1.00 41.87  ? 328 ALA B N   1 
ATOM   8330 C CA  . ALA D 4 346 ? 149.051 160.731 184.852 1.00 52.49  ? 328 ALA B CA  1 
ATOM   8331 C C   . ALA D 4 346 ? 149.314 159.257 184.591 1.00 62.32  ? 328 ALA B C   1 
ATOM   8332 O O   . ALA D 4 346 ? 149.571 158.495 185.528 1.00 70.77  ? 328 ALA B O   1 
ATOM   8333 C CB  . ALA D 4 346 ? 150.337 161.439 185.276 1.00 59.99  ? 328 ALA B CB  1 
ATOM   8334 N N   . THR D 4 347 ? 149.262 158.863 183.320 1.00 67.57  ? 329 THR B N   1 
ATOM   8335 C CA  . THR D 4 347 ? 149.413 157.470 182.918 1.00 62.98  ? 329 THR B CA  1 
ATOM   8336 C C   . THR D 4 347 ? 150.542 157.336 181.908 1.00 59.01  ? 329 THR B C   1 
ATOM   8337 O O   . THR D 4 347 ? 150.582 158.065 180.913 1.00 70.60  ? 329 THR B O   1 
ATOM   8338 C CB  . THR D 4 347 ? 148.118 156.917 182.314 1.00 64.31  ? 329 THR B CB  1 
ATOM   8339 O OG1 . THR D 4 347 ? 147.871 157.548 181.052 1.00 69.73  ? 329 THR B OG1 1 
ATOM   8340 C CG2 . THR D 4 347 ? 146.941 157.169 183.241 1.00 68.28  ? 329 THR B CG2 1 
ATOM   8341 N N   . GLY D 4 348 ? 151.444 156.392 182.159 1.00 51.69  ? 330 GLY B N   1 
ATOM   8342 C CA  . GLY D 4 348 ? 152.509 156.068 181.233 1.00 58.07  ? 330 GLY B CA  1 
ATOM   8343 C C   . GLY D 4 348 ? 152.420 154.635 180.754 1.00 63.87  ? 330 GLY B C   1 
ATOM   8344 O O   . GLY D 4 348 ? 152.207 153.715 181.553 1.00 72.04  ? 330 GLY B O   1 
ATOM   8345 N N   . SER D 4 349 ? 152.586 154.431 179.454 1.00 67.96  ? 331 SER B N   1 
ATOM   8346 C CA  . SER D 4 349 ? 152.397 153.136 178.819 1.00 68.13  ? 331 SER B CA  1 
ATOM   8347 C C   . SER D 4 349 ? 153.682 152.710 178.115 1.00 71.08  ? 331 SER B C   1 
ATOM   8348 O O   . SER D 4 349 ? 154.710 153.385 178.186 1.00 75.34  ? 331 SER B O   1 
ATOM   8349 C CB  . SER D 4 349 ? 151.235 153.179 177.825 1.00 50.00  ? 331 SER B CB  1 
ATOM   8350 O OG  . SER D 4 349 ? 151.512 154.067 176.755 1.00 50.00  ? 331 SER B OG  1 
ATOM   8351 N N   . TRP D 4 350 ? 153.614 151.565 177.429 1.00 75.47  ? 332 TRP B N   1 
ATOM   8352 C CA  . TRP D 4 350 ? 154.815 151.003 176.822 1.00 73.42  ? 332 TRP B CA  1 
ATOM   8353 C C   . TRP D 4 350 ? 155.259 151.795 175.602 1.00 76.10  ? 332 TRP B C   1 
ATOM   8354 O O   . TRP D 4 350 ? 156.450 151.797 175.272 1.00 85.91  ? 332 TRP B O   1 
ATOM   8355 C CB  . TRP D 4 350 ? 154.596 149.536 176.461 1.00 77.13  ? 332 TRP B CB  1 
ATOM   8356 C CG  . TRP D 4 350 ? 155.041 148.599 177.542 1.00 78.45  ? 332 TRP B CG  1 
ATOM   8357 C CD1 . TRP D 4 350 ? 155.205 148.895 178.862 1.00 80.03  ? 332 TRP B CD1 1 
ATOM   8358 C CD2 . TRP D 4 350 ? 155.384 147.216 177.396 1.00 76.35  ? 332 TRP B CD2 1 
ATOM   8359 N NE1 . TRP D 4 350 ? 155.627 147.783 179.548 1.00 79.24  ? 332 TRP B NE1 1 
ATOM   8360 C CE2 . TRP D 4 350 ? 155.743 146.739 178.670 1.00 74.87  ? 332 TRP B CE2 1 
ATOM   8361 C CE3 . TRP D 4 350 ? 155.420 146.336 176.312 1.00 78.12  ? 332 TRP B CE3 1 
ATOM   8362 C CZ2 . TRP D 4 350 ? 156.135 145.422 178.890 1.00 77.12  ? 332 TRP B CZ2 1 
ATOM   8363 C CZ3 . TRP D 4 350 ? 155.808 145.029 176.533 1.00 82.27  ? 332 TRP B CZ3 1 
ATOM   8364 C CH2 . TRP D 4 350 ? 156.160 144.585 177.810 1.00 81.31  ? 332 TRP B CH2 1 
ATOM   8365 N N   . ASP D 4 351 ? 154.338 152.466 174.918 1.00 70.83  ? 333 ASP B N   1 
ATOM   8366 C CA  . ASP D 4 351 ? 154.760 153.459 173.945 1.00 75.07  ? 333 ASP B CA  1 
ATOM   8367 C C   . ASP D 4 351 ? 155.418 154.622 174.678 1.00 79.89  ? 333 ASP B C   1 
ATOM   8368 O O   . ASP D 4 351 ? 155.097 154.916 175.832 1.00 88.16  ? 333 ASP B O   1 
ATOM   8369 C CB  . ASP D 4 351 ? 153.577 153.940 173.104 1.00 80.11  ? 333 ASP B CB  1 
ATOM   8370 C CG  . ASP D 4 351 ? 152.498 154.596 173.935 1.00 85.99  ? 333 ASP B CG  1 
ATOM   8371 O OD1 . ASP D 4 351 ? 152.841 155.363 174.855 1.00 85.92  ? 333 ASP B OD1 1 
ATOM   8372 O OD2 . ASP D 4 351 ? 151.304 154.343 173.670 1.00 80.14  ? 333 ASP B OD2 1 
ATOM   8373 N N   . SER D 4 352 ? 156.355 155.284 173.997 1.00 61.08  ? 334 SER B N   1 
ATOM   8374 C CA  . SER D 4 352 ? 157.228 156.241 174.667 1.00 64.54  ? 334 SER B CA  1 
ATOM   8375 C C   . SER D 4 352 ? 156.467 157.383 175.329 1.00 68.18  ? 334 SER B C   1 
ATOM   8376 O O   . SER D 4 352 ? 157.005 158.022 176.240 1.00 66.93  ? 334 SER B O   1 
ATOM   8377 C CB  . SER D 4 352 ? 158.241 156.806 173.672 1.00 71.49  ? 334 SER B CB  1 
ATOM   8378 O OG  . SER D 4 352 ? 158.954 155.766 173.028 1.00 74.18  ? 334 SER B OG  1 
ATOM   8379 N N   . PHE D 4 353 ? 155.239 157.653 174.904 1.00 73.74  ? 335 PHE B N   1 
ATOM   8380 C CA  . PHE D 4 353 ? 154.494 158.788 175.426 1.00 72.41  ? 335 PHE B CA  1 
ATOM   8381 C C   . PHE D 4 353 ? 153.848 158.458 176.765 1.00 71.60  ? 335 PHE B C   1 
ATOM   8382 O O   . PHE D 4 353 ? 153.520 157.304 177.057 1.00 75.37  ? 335 PHE B O   1 
ATOM   8383 C CB  . PHE D 4 353 ? 153.413 159.218 174.435 1.00 71.35  ? 335 PHE B CB  1 
ATOM   8384 C CG  . PHE D 4 353 ? 153.845 159.154 173.003 1.00 74.12  ? 335 PHE B CG  1 
ATOM   8385 C CD1 . PHE D 4 353 ? 154.731 160.082 172.492 1.00 72.28  ? 335 PHE B CD1 1 
ATOM   8386 C CD2 . PHE D 4 353 ? 153.365 158.163 172.167 1.00 78.36  ? 335 PHE B CD2 1 
ATOM   8387 C CE1 . PHE D 4 353 ? 155.131 160.025 171.175 1.00 76.01  ? 335 PHE B CE1 1 
ATOM   8388 C CE2 . PHE D 4 353 ? 153.761 158.100 170.848 1.00 79.54  ? 335 PHE B CE2 1 
ATOM   8389 C CZ  . PHE D 4 353 ? 154.646 159.033 170.351 1.00 77.88  ? 335 PHE B CZ  1 
ATOM   8390 N N   . LEU D 4 354 ? 153.667 159.493 177.583 1.00 63.82  ? 336 LEU B N   1 
ATOM   8391 C CA  . LEU D 4 354 ? 152.817 159.424 178.761 1.00 60.06  ? 336 LEU B CA  1 
ATOM   8392 C C   . LEU D 4 354 ? 151.919 160.652 178.773 1.00 58.24  ? 336 LEU B C   1 
ATOM   8393 O O   . LEU D 4 354 ? 152.301 161.723 178.296 1.00 66.84  ? 336 LEU B O   1 
ATOM   8394 C CB  . LEU D 4 354 ? 153.635 159.320 180.064 1.00 59.37  ? 336 LEU B CB  1 
ATOM   8395 C CG  . LEU D 4 354 ? 154.612 160.406 180.519 1.00 62.31  ? 336 LEU B CG  1 
ATOM   8396 C CD1 . LEU D 4 354 ? 153.891 161.521 181.251 1.00 69.01  ? 336 LEU B CD1 1 
ATOM   8397 C CD2 . LEU D 4 354 ? 155.683 159.813 181.406 1.00 56.02  ? 336 LEU B CD2 1 
ATOM   8398 N N   . LYS D 4 355 ? 150.721 160.488 179.321 1.00 53.66  ? 337 LYS B N   1 
ATOM   8399 C CA  . LYS D 4 355 ? 149.674 161.489 179.203 1.00 54.79  ? 337 LYS B CA  1 
ATOM   8400 C C   . LYS D 4 355 ? 149.180 161.921 180.575 1.00 58.64  ? 337 LYS B C   1 
ATOM   8401 O O   . LYS D 4 355 ? 149.310 161.200 181.569 1.00 66.82  ? 337 LYS B O   1 
ATOM   8402 C CB  . LYS D 4 355 ? 148.495 160.959 178.379 1.00 63.14  ? 337 LYS B CB  1 
ATOM   8403 C CG  . LYS D 4 355 ? 148.774 160.843 176.893 1.00 71.08  ? 337 LYS B CG  1 
ATOM   8404 C CD  . LYS D 4 355 ? 147.483 160.781 176.098 1.00 66.72  ? 337 LYS B CD  1 
ATOM   8405 C CE  . LYS D 4 355 ? 147.734 160.326 174.673 1.00 63.77  ? 337 LYS B CE  1 
ATOM   8406 N NZ  . LYS D 4 355 ? 148.928 160.991 174.089 1.00 66.70  ? 337 LYS B NZ  1 
ATOM   8407 N N   . ILE D 4 356 ? 148.611 163.123 180.611 1.00 55.84  ? 338 ILE B N   1 
ATOM   8408 C CA  . ILE D 4 356 ? 147.990 163.684 181.803 1.00 55.13  ? 338 ILE B CA  1 
ATOM   8409 C C   . ILE D 4 356 ? 146.531 163.964 181.482 1.00 56.22  ? 338 ILE B C   1 
ATOM   8410 O O   . ILE D 4 356 ? 146.227 164.634 180.488 1.00 70.37  ? 338 ILE B O   1 
ATOM   8411 C CB  . ILE D 4 356 ? 148.706 164.962 182.273 1.00 55.16  ? 338 ILE B CB  1 
ATOM   8412 C CG1 . ILE D 4 356 ? 150.107 164.627 182.783 1.00 61.76  ? 338 ILE B CG1 1 
ATOM   8413 C CG2 . ILE D 4 356 ? 147.900 165.654 183.352 1.00 56.50  ? 338 ILE B CG2 1 
ATOM   8414 C CD1 . ILE D 4 356 ? 150.977 165.836 183.012 1.00 61.70  ? 338 ILE B CD1 1 
ATOM   8415 N N   . TRP D 4 357 ? 145.635 163.450 182.317 1.00 50.83  ? 339 TRP B N   1 
ATOM   8416 C CA  . TRP D 4 357 ? 144.202 163.514 182.099 1.00 55.53  ? 339 TRP B CA  1 
ATOM   8417 C C   . TRP D 4 357 ? 143.556 164.308 183.222 1.00 60.37  ? 339 TRP B C   1 
ATOM   8418 O O   . TRP D 4 357 ? 143.919 164.155 184.395 1.00 69.95  ? 339 TRP B O   1 
ATOM   8419 C CB  . TRP D 4 357 ? 143.581 162.112 182.043 1.00 59.05  ? 339 TRP B CB  1 
ATOM   8420 C CG  . TRP D 4 357 ? 144.358 161.112 181.241 1.00 60.98  ? 339 TRP B CG  1 
ATOM   8421 C CD1 . TRP D 4 357 ? 145.563 160.562 181.561 1.00 65.39  ? 339 TRP B CD1 1 
ATOM   8422 C CD2 . TRP D 4 357 ? 143.966 160.519 179.998 1.00 58.24  ? 339 TRP B CD2 1 
ATOM   8423 N NE1 . TRP D 4 357 ? 145.954 159.678 180.588 1.00 64.81  ? 339 TRP B NE1 1 
ATOM   8424 C CE2 . TRP D 4 357 ? 144.990 159.633 179.618 1.00 57.58  ? 339 TRP B CE2 1 
ATOM   8425 C CE3 . TRP D 4 357 ? 142.853 160.660 179.166 1.00 64.36  ? 339 TRP B CE3 1 
ATOM   8426 C CZ2 . TRP D 4 357 ? 144.934 158.890 178.445 1.00 60.77  ? 339 TRP B CZ2 1 
ATOM   8427 C CZ3 . TRP D 4 357 ? 142.799 159.921 178.004 1.00 68.42  ? 339 TRP B CZ3 1 
ATOM   8428 C CH2 . TRP D 4 357 ? 143.832 159.048 177.652 1.00 66.73  ? 339 TRP B CH2 1 
ATOM   8429 N N   . ASN D 4 358 ? 142.597 165.148 182.852 1.00 73.26  ? 340 ASN B N   1 
ATOM   8430 C CA  . ASN D 4 358 ? 141.867 165.949 183.828 1.00 72.54  ? 340 ASN B CA  1 
ATOM   8431 C C   . ASN D 4 358 ? 140.377 165.978 183.509 1.00 75.77  ? 340 ASN B C   1 
ATOM   8432 O O   . ASN D 4 358 ? 139.965 165.678 182.389 1.00 82.19  ? 340 ASN B O   1 
ATOM   8433 C CB  . ASN D 4 358 ? 142.423 167.371 183.877 1.00 75.44  ? 340 ASN B CB  1 
ATOM   8434 C CG  . ASN D 4 358 ? 142.097 168.079 185.174 1.00 79.08  ? 340 ASN B CG  1 
ATOM   8435 O OD1 . ASN D 4 358 ? 141.390 167.544 186.026 1.00 79.74  ? 340 ASN B OD1 1 
ATOM   8436 N ND2 . ASN D 4 358 ? 142.613 169.292 185.331 1.00 80.46  ? 340 ASN B ND2 1 
ATOM   8437 O OXT . ASN D 4 358 ? 139.550 166.300 184.359 1.00 71.50  ? 340 ASN B OXT 1 
ATOM   8438 N N   . ALA E 5 7   ? 166.548 121.079 208.941 1.00 134.00 ? 7   ALA C N   1 
ATOM   8439 C CA  . ALA E 5 7   ? 166.011 121.729 207.752 1.00 134.95 ? 7   ALA C CA  1 
ATOM   8440 C C   . ALA E 5 7   ? 164.601 121.234 207.450 1.00 136.42 ? 7   ALA C C   1 
ATOM   8441 O O   . ALA E 5 7   ? 164.073 121.462 206.362 1.00 135.62 ? 7   ALA C O   1 
ATOM   8442 C CB  . ALA E 5 7   ? 166.925 121.492 206.559 1.00 133.43 ? 7   ALA C CB  1 
ATOM   8443 N N   . SER E 5 8   ? 164.000 120.552 208.418 1.00 133.04 ? 8   SER C N   1 
ATOM   8444 C CA  . SER E 5 8   ? 162.648 120.024 208.284 1.00 131.34 ? 8   SER C CA  1 
ATOM   8445 C C   . SER E 5 8   ? 161.712 120.485 209.387 1.00 129.32 ? 8   SER C C   1 
ATOM   8446 O O   . SER E 5 8   ? 160.536 120.746 209.121 1.00 129.44 ? 8   SER C O   1 
ATOM   8447 C CB  . SER E 5 8   ? 162.682 118.489 208.256 1.00 131.12 ? 8   SER C CB  1 
ATOM   8448 O OG  . SER E 5 8   ? 163.765 118.018 207.473 1.00 130.88 ? 8   SER C OG  1 
ATOM   8449 N N   . ILE E 5 9   ? 162.202 120.597 210.618 1.00 127.11 ? 9   ILE C N   1 
ATOM   8450 C CA  . ILE E 5 9   ? 161.351 120.998 211.731 1.00 129.38 ? 9   ILE C CA  1 
ATOM   8451 C C   . ILE E 5 9   ? 161.294 122.517 211.888 1.00 130.30 ? 9   ILE C C   1 
ATOM   8452 O O   . ILE E 5 9   ? 160.284 123.050 212.360 1.00 128.84 ? 9   ILE C O   1 
ATOM   8453 C CB  . ILE E 5 9   ? 161.832 120.330 213.032 1.00 129.54 ? 9   ILE C CB  1 
ATOM   8454 C CG1 . ILE E 5 9   ? 162.128 118.847 212.799 1.00 128.70 ? 9   ILE C CG1 1 
ATOM   8455 C CG2 . ILE E 5 9   ? 160.796 120.489 214.134 1.00 128.63 ? 9   ILE C CG2 1 
ATOM   8456 C CD1 . ILE E 5 9   ? 163.606 118.522 212.705 1.00 127.93 ? 9   ILE C CD1 1 
ATOM   8457 N N   . ALA E 5 10  ? 162.358 123.225 211.500 1.00 127.53 ? 10  ALA C N   1 
ATOM   8458 C CA  . ALA E 5 10  ? 162.418 124.666 211.723 1.00 127.88 ? 10  ALA C CA  1 
ATOM   8459 C C   . ALA E 5 10  ? 161.329 125.398 210.946 1.00 128.09 ? 10  ALA C C   1 
ATOM   8460 O O   . ALA E 5 10  ? 160.642 126.270 211.491 1.00 127.10 ? 10  ALA C O   1 
ATOM   8461 C CB  . ALA E 5 10  ? 163.801 125.195 211.341 1.00 125.87 ? 10  ALA C CB  1 
ATOM   8462 N N   . GLN E 5 11  ? 161.158 125.058 209.666 1.00 127.92 ? 11  GLN C N   1 
ATOM   8463 C CA  . GLN E 5 11  ? 160.155 125.740 208.854 1.00 127.44 ? 11  GLN C CA  1 
ATOM   8464 C C   . GLN E 5 11  ? 158.744 125.436 209.344 1.00 127.10 ? 11  GLN C C   1 
ATOM   8465 O O   . GLN E 5 11  ? 157.888 126.329 209.376 1.00 128.46 ? 11  GLN C O   1 
ATOM   8466 C CB  . GLN E 5 11  ? 160.313 125.359 207.381 1.00 125.85 ? 11  GLN C CB  1 
ATOM   8467 C CG  . GLN E 5 11  ? 160.250 123.868 207.097 1.00 126.60 ? 11  GLN C CG  1 
ATOM   8468 C CD  . GLN E 5 11  ? 161.615 123.213 207.128 1.00 127.68 ? 11  GLN C CD  1 
ATOM   8469 O OE1 . GLN E 5 11  ? 162.343 123.316 208.115 1.00 127.84 ? 11  GLN C OE1 1 
ATOM   8470 N NE2 . GLN E 5 11  ? 161.969 122.533 206.044 1.00 127.54 ? 11  GLN C NE2 1 
ATOM   8471 N N   . ALA E 5 12  ? 158.482 124.186 209.731 1.00 118.25 ? 12  ALA C N   1 
ATOM   8472 C CA  . ALA E 5 12  ? 157.167 123.840 210.258 1.00 118.74 ? 12  ALA C CA  1 
ATOM   8473 C C   . ALA E 5 12  ? 156.883 124.589 211.553 1.00 118.32 ? 12  ALA C C   1 
ATOM   8474 O O   . ALA E 5 12  ? 155.772 125.096 211.755 1.00 120.03 ? 12  ALA C O   1 
ATOM   8475 C CB  . ALA E 5 12  ? 157.067 122.331 210.473 1.00 120.30 ? 12  ALA C CB  1 
ATOM   8476 N N   . ARG E 5 13  ? 157.877 124.673 212.440 1.00 110.36 ? 13  ARG C N   1 
ATOM   8477 C CA  . ARG E 5 13  ? 157.695 125.409 213.686 1.00 112.78 ? 13  ARG C CA  1 
ATOM   8478 C C   . ARG E 5 13  ? 157.443 126.887 213.420 1.00 115.76 ? 13  ARG C C   1 
ATOM   8479 O O   . ARG E 5 13  ? 156.575 127.501 214.052 1.00 115.28 ? 13  ARG C O   1 
ATOM   8480 C CB  . ARG E 5 13  ? 158.916 125.239 214.592 1.00 50.00  ? 13  ARG C CB  1 
ATOM   8481 C CG  . ARG E 5 13  ? 159.108 123.824 215.115 1.00 50.00  ? 13  ARG C CG  1 
ATOM   8482 C CD  . ARG E 5 13  ? 160.293 123.664 216.054 1.00 50.00  ? 13  ARG C CD  1 
ATOM   8483 N NE  . ARG E 5 13  ? 160.477 122.278 216.472 1.00 50.00  ? 13  ARG C NE  1 
ATOM   8484 C CZ  . ARG E 5 13  ? 161.500 121.848 217.196 1.00 50.00  ? 13  ARG C CZ  1 
ATOM   8485 N NH1 . ARG E 5 13  ? 162.441 122.698 217.590 1.00 50.00  ? 13  ARG C NH1 1 
ATOM   8486 N NH2 . ARG E 5 13  ? 161.588 120.567 217.531 1.00 50.00  ? 13  ARG C NH2 1 
ATOM   8487 N N   . LYS E 5 14  ? 158.192 127.478 212.485 1.00 118.02 ? 14  LYS C N   1 
ATOM   8488 C CA  . LYS E 5 14  ? 157.988 128.885 212.157 1.00 118.41 ? 14  LYS C CA  1 
ATOM   8489 C C   . LYS E 5 14  ? 156.594 129.121 211.592 1.00 117.71 ? 14  LYS C C   1 
ATOM   8490 O O   . LYS E 5 14  ? 155.916 130.085 211.970 1.00 116.70 ? 14  LYS C O   1 
ATOM   8491 C CB  . LYS E 5 14  ? 159.057 129.354 211.170 1.00 117.06 ? 14  LYS C CB  1 
ATOM   8492 C CG  . LYS E 5 14  ? 159.293 130.855 211.176 1.00 118.87 ? 14  LYS C CG  1 
ATOM   8493 N N   . LEU E 5 15  ? 156.145 128.245 210.691 1.00 111.91 ? 15  LEU C N   1 
ATOM   8494 C CA  . LEU E 5 15  ? 154.812 128.396 210.118 1.00 109.45 ? 15  LEU C CA  1 
ATOM   8495 C C   . LEU E 5 15  ? 153.736 128.266 211.188 1.00 110.75 ? 15  LEU C C   1 
ATOM   8496 O O   . LEU E 5 15  ? 152.781 129.054 211.218 1.00 115.03 ? 15  LEU C O   1 
ATOM   8497 C CB  . LEU E 5 15  ? 154.604 127.365 209.009 1.00 109.49 ? 15  LEU C CB  1 
ATOM   8498 C CG  . LEU E 5 15  ? 153.476 127.622 208.007 1.00 110.89 ? 15  LEU C CG  1 
ATOM   8499 C CD1 . LEU E 5 15  ? 153.886 127.152 206.620 1.00 110.13 ? 15  LEU C CD1 1 
ATOM   8500 C CD2 . LEU E 5 15  ? 152.196 126.930 208.443 1.00 112.05 ? 15  LEU C CD2 1 
ATOM   8501 N N   . VAL E 5 16  ? 153.881 127.291 212.088 1.00 110.75 ? 16  VAL C N   1 
ATOM   8502 C CA  . VAL E 5 16  ? 152.850 127.076 213.096 1.00 114.87 ? 16  VAL C CA  1 
ATOM   8503 C C   . VAL E 5 16  ? 152.817 128.234 214.089 1.00 117.14 ? 16  VAL C C   1 
ATOM   8504 O O   . VAL E 5 16  ? 151.738 128.663 214.517 1.00 119.04 ? 16  VAL C O   1 
ATOM   8505 C CB  . VAL E 5 16  ? 153.036 125.709 213.787 1.00 116.85 ? 16  VAL C CB  1 
ATOM   8506 C CG1 . VAL E 5 16  ? 154.112 125.751 214.863 1.00 116.81 ? 16  VAL C CG1 1 
ATOM   8507 C CG2 . VAL E 5 16  ? 151.716 125.227 214.367 1.00 117.73 ? 16  VAL C CG2 1 
ATOM   8508 N N   . GLU E 5 17  ? 153.981 128.793 214.443 1.00 110.10 ? 17  GLU C N   1 
ATOM   8509 C CA  . GLU E 5 17  ? 153.964 129.916 215.374 1.00 110.58 ? 17  GLU C CA  1 
ATOM   8510 C C   . GLU E 5 17  ? 153.441 131.185 214.711 1.00 112.69 ? 17  GLU C C   1 
ATOM   8511 O O   . GLU E 5 17  ? 152.759 131.983 215.364 1.00 111.33 ? 17  GLU C O   1 
ATOM   8512 C CB  . GLU E 5 17  ? 155.350 130.151 215.979 1.00 110.36 ? 17  GLU C CB  1 
ATOM   8513 C CG  . GLU E 5 17  ? 156.437 130.536 215.000 1.00 113.62 ? 17  GLU C CG  1 
ATOM   8514 C CD  . GLU E 5 17  ? 157.820 130.480 215.622 1.00 115.53 ? 17  GLU C CD  1 
ATOM   8515 O OE1 . GLU E 5 17  ? 158.115 131.327 216.493 1.00 113.73 ? 17  GLU C OE1 1 
ATOM   8516 O OE2 . GLU E 5 17  ? 158.610 129.589 215.248 1.00 117.44 ? 17  GLU C OE2 1 
ATOM   8517 N N   . GLN E 5 18  ? 153.728 131.386 213.421 1.00 106.21 ? 18  GLN C N   1 
ATOM   8518 C CA  . GLN E 5 18  ? 153.145 132.525 212.720 1.00 102.38 ? 18  GLN C CA  1 
ATOM   8519 C C   . GLN E 5 18  ? 151.629 132.405 212.643 1.00 100.09 ? 18  GLN C C   1 
ATOM   8520 O O   . GLN E 5 18  ? 150.908 133.394 212.832 1.00 99.48  ? 18  GLN C O   1 
ATOM   8521 C CB  . GLN E 5 18  ? 153.744 132.650 211.321 1.00 101.11 ? 18  GLN C CB  1 
ATOM   8522 C CG  . GLN E 5 18  ? 153.437 133.971 210.644 1.00 99.13  ? 18  GLN C CG  1 
ATOM   8523 C CD  . GLN E 5 18  ? 153.847 135.159 211.487 1.00 101.17 ? 18  GLN C CD  1 
ATOM   8524 O OE1 . GLN E 5 18  ? 153.040 136.044 211.769 1.00 103.58 ? 18  GLN C OE1 1 
ATOM   8525 N NE2 . GLN E 5 18  ? 155.109 135.185 211.896 1.00 101.33 ? 18  GLN C NE2 1 
ATOM   8526 N N   . LEU E 5 19  ? 151.125 131.200 212.369 1.00 104.45 ? 19  LEU C N   1 
ATOM   8527 C CA  . LEU E 5 19  ? 149.679 131.005 212.343 1.00 104.50 ? 19  LEU C CA  1 
ATOM   8528 C C   . LEU E 5 19  ? 149.070 131.229 213.721 1.00 106.40 ? 19  LEU C C   1 
ATOM   8529 O O   . LEU E 5 19  ? 147.987 131.815 213.842 1.00 109.60 ? 19  LEU C O   1 
ATOM   8530 C CB  . LEU E 5 19  ? 149.344 129.610 211.820 1.00 104.87 ? 19  LEU C CB  1 
ATOM   8531 C CG  . LEU E 5 19  ? 149.277 129.488 210.297 1.00 106.81 ? 19  LEU C CG  1 
ATOM   8532 C CD1 . LEU E 5 19  ? 149.006 128.051 209.884 1.00 107.47 ? 19  LEU C CD1 1 
ATOM   8533 C CD2 . LEU E 5 19  ? 148.221 130.422 209.730 1.00 105.81 ? 19  LEU C CD2 1 
ATOM   8534 N N   . LYS E 5 20  ? 149.754 130.775 214.774 1.00 103.38 ? 20  LYS C N   1 
ATOM   8535 C CA  . LYS E 5 20  ? 149.275 131.024 216.129 1.00 105.39 ? 20  LYS C CA  1 
ATOM   8536 C C   . LYS E 5 20  ? 149.211 132.517 216.423 1.00 104.91 ? 20  LYS C C   1 
ATOM   8537 O O   . LYS E 5 20  ? 148.249 132.997 217.034 1.00 106.16 ? 20  LYS C O   1 
ATOM   8538 C CB  . LYS E 5 20  ? 150.176 130.318 217.142 1.00 108.83 ? 20  LYS C CB  1 
ATOM   8539 C CG  . LYS E 5 20  ? 149.910 128.830 217.287 1.00 109.81 ? 20  LYS C CG  1 
ATOM   8540 C CD  . LYS E 5 20  ? 149.219 128.519 218.604 1.00 107.88 ? 20  LYS C CD  1 
ATOM   8541 C CE  . LYS E 5 20  ? 149.641 127.160 219.138 1.00 105.05 ? 20  LYS C CE  1 
ATOM   8542 N NZ  . LYS E 5 20  ? 150.814 127.265 220.049 1.00 104.54 ? 20  LYS C NZ  1 
ATOM   8543 N N   . MET E 5 21  ? 150.232 133.266 216.001 1.00 99.47  ? 21  MET C N   1 
ATOM   8544 C CA  . MET E 5 21  ? 150.230 134.709 216.217 1.00 101.21 ? 21  MET C CA  1 
ATOM   8545 C C   . MET E 5 21  ? 149.097 135.384 215.454 1.00 100.43 ? 21  MET C C   1 
ATOM   8546 O O   . MET E 5 21  ? 148.453 136.305 215.969 1.00 96.59  ? 21  MET C O   1 
ATOM   8547 C CB  . MET E 5 21  ? 151.578 135.303 215.812 1.00 103.56 ? 21  MET C CB  1 
ATOM   8548 C CG  . MET E 5 21  ? 152.567 135.437 216.958 1.00 102.46 ? 21  MET C CG  1 
ATOM   8549 S SD  . MET E 5 21  ? 154.163 136.083 216.429 1.00 107.75 ? 21  MET C SD  1 
ATOM   8550 C CE  . MET E 5 21  ? 153.672 137.111 215.048 1.00 97.35  ? 21  MET C CE  1 
ATOM   8551 N N   . GLU E 5 22  ? 148.842 134.947 214.220 1.00 98.58  ? 22  GLU C N   1 
ATOM   8552 C CA  . GLU E 5 22  ? 147.752 135.529 213.446 1.00 94.52  ? 22  GLU C CA  1 
ATOM   8553 C C   . GLU E 5 22  ? 146.379 135.066 213.914 1.00 97.41  ? 22  GLU C C   1 
ATOM   8554 O O   . GLU E 5 22  ? 145.375 135.659 213.509 1.00 98.10  ? 22  GLU C O   1 
ATOM   8555 C CB  . GLU E 5 22  ? 147.920 135.198 211.963 1.00 94.65  ? 22  GLU C CB  1 
ATOM   8556 C CG  . GLU E 5 22  ? 148.656 136.260 211.169 1.00 98.52  ? 22  GLU C CG  1 
ATOM   8557 N N   . ALA E 5 23  ? 146.311 134.024 214.745 1.00 101.11 ? 23  ALA C N   1 
ATOM   8558 C CA  . ALA E 5 23  ? 145.017 133.494 215.164 1.00 101.21 ? 23  ALA C CA  1 
ATOM   8559 C C   . ALA E 5 23  ? 144.256 134.474 216.049 1.00 101.16 ? 23  ALA C C   1 
ATOM   8560 O O   . ALA E 5 23  ? 143.036 134.623 215.910 1.00 98.88  ? 23  ALA C O   1 
ATOM   8561 C CB  . ALA E 5 23  ? 145.209 132.161 215.887 1.00 100.94 ? 23  ALA C CB  1 
ATOM   8562 N N   . ASN E 5 24  ? 144.949 135.155 216.959 1.00 102.92 ? 24  ASN C N   1 
ATOM   8563 C CA  . ASN E 5 24  ? 144.306 135.914 218.032 1.00 102.44 ? 24  ASN C CA  1 
ATOM   8564 C C   . ASN E 5 24  ? 144.223 137.407 217.736 1.00 104.75 ? 24  ASN C C   1 
ATOM   8565 O O   . ASN E 5 24  ? 144.370 138.231 218.643 1.00 106.43 ? 24  ASN C O   1 
ATOM   8566 C CB  . ASN E 5 24  ? 145.032 135.675 219.351 1.00 102.22 ? 24  ASN C CB  1 
ATOM   8567 C CG  . ASN E 5 24  ? 146.532 135.826 219.225 1.00 102.85 ? 24  ASN C CG  1 
ATOM   8568 O OD1 . ASN E 5 24  ? 147.124 135.420 218.227 1.00 103.92 ? 24  ASN C OD1 1 
ATOM   8569 N ND2 . ASN E 5 24  ? 147.155 136.413 220.239 1.00 101.88 ? 24  ASN C ND2 1 
ATOM   8570 N N   . ILE E 5 25  ? 143.993 137.791 216.486 1.00 104.68 ? 25  ILE C N   1 
ATOM   8571 C CA  . ILE E 5 25  ? 143.807 139.193 216.129 1.00 103.25 ? 25  ILE C CA  1 
ATOM   8572 C C   . ILE E 5 25  ? 142.330 139.537 216.267 1.00 100.47 ? 25  ILE C C   1 
ATOM   8573 O O   . ILE E 5 25  ? 141.464 138.823 215.745 1.00 102.09 ? 25  ILE C O   1 
ATOM   8574 C CB  . ILE E 5 25  ? 144.315 139.471 214.704 1.00 104.16 ? 25  ILE C CB  1 
ATOM   8575 C CG1 . ILE E 5 25  ? 145.809 139.796 214.730 1.00 103.26 ? 25  ILE C CG1 1 
ATOM   8576 C CG2 . ILE E 5 25  ? 143.538 140.611 214.062 1.00 100.08 ? 25  ILE C CG2 1 
ATOM   8577 C CD1 . ILE E 5 25  ? 146.127 141.179 215.253 1.00 99.90  ? 25  ILE C CD1 1 
ATOM   8578 N N   . ASP E 5 26  ? 142.039 140.620 216.984 1.00 95.65  ? 26  ASP C N   1 
ATOM   8579 C CA  . ASP E 5 26  ? 140.660 141.040 217.186 1.00 98.10  ? 26  ASP C CA  1 
ATOM   8580 C C   . ASP E 5 26  ? 140.023 141.454 215.865 1.00 99.54  ? 26  ASP C C   1 
ATOM   8581 O O   . ASP E 5 26  ? 140.666 142.071 215.012 1.00 103.35 ? 26  ASP C O   1 
ATOM   8582 C CB  . ASP E 5 26  ? 140.598 142.194 218.184 1.00 101.33 ? 26  ASP C CB  1 
ATOM   8583 C CG  . ASP E 5 26  ? 139.237 142.327 218.839 1.00 106.67 ? 26  ASP C CG  1 
ATOM   8584 O OD1 . ASP E 5 26  ? 138.275 141.696 218.352 1.00 108.91 ? 26  ASP C OD1 1 
ATOM   8585 O OD2 . ASP E 5 26  ? 139.128 143.063 219.843 1.00 105.97 ? 26  ASP C OD2 1 
ATOM   8586 N N   . ARG E 5 27  ? 138.746 141.113 215.702 1.00 88.85  ? 27  ARG C N   1 
ATOM   8587 C CA  . ARG E 5 27  ? 138.015 141.373 214.471 1.00 92.24  ? 27  ARG C CA  1 
ATOM   8588 C C   . ARG E 5 27  ? 136.744 142.152 214.776 1.00 93.46  ? 27  ARG C C   1 
ATOM   8589 O O   . ARG E 5 27  ? 136.227 142.115 215.895 1.00 93.36  ? 27  ARG C O   1 
ATOM   8590 C CB  . ARG E 5 27  ? 137.664 140.070 213.743 1.00 94.28  ? 27  ARG C CB  1 
ATOM   8591 C CG  . ARG E 5 27  ? 138.804 139.069 213.674 1.00 93.98  ? 27  ARG C CG  1 
ATOM   8592 C CD  . ARG E 5 27  ? 138.605 138.075 212.540 1.00 94.07  ? 27  ARG C CD  1 
ATOM   8593 N NE  . ARG E 5 27  ? 139.500 136.927 212.642 1.00 96.15  ? 27  ARG C NE  1 
ATOM   8594 C CZ  . ARG E 5 27  ? 140.814 136.975 212.472 1.00 96.88  ? 27  ARG C CZ  1 
ATOM   8595 N NH1 . ARG E 5 27  ? 141.432 138.102 212.157 1.00 96.69  ? 27  ARG C NH1 1 
ATOM   8596 N NH2 . ARG E 5 27  ? 141.527 135.862 212.613 1.00 96.05  ? 27  ARG C NH2 1 
ATOM   8597 N N   . ILE E 5 28  ? 136.247 142.859 213.766 1.00 86.50  ? 28  ILE C N   1 
ATOM   8598 C CA  . ILE E 5 28  ? 135.043 143.665 213.892 1.00 82.97  ? 28  ILE C CA  1 
ATOM   8599 C C   . ILE E 5 28  ? 134.034 143.221 212.837 1.00 87.51  ? 28  ILE C C   1 
ATOM   8600 O O   . ILE E 5 28  ? 134.331 142.416 211.955 1.00 90.04  ? 28  ILE C O   1 
ATOM   8601 C CB  . ILE E 5 28  ? 135.339 145.172 213.769 1.00 80.69  ? 28  ILE C CB  1 
ATOM   8602 C CG1 . ILE E 5 28  ? 135.708 145.524 212.328 1.00 82.76  ? 28  ILE C CG1 1 
ATOM   8603 C CG2 . ILE E 5 28  ? 136.450 145.579 214.721 1.00 84.00  ? 28  ILE C CG2 1 
ATOM   8604 C CD1 . ILE E 5 28  ? 136.003 146.989 212.117 1.00 87.34  ? 28  ILE C CD1 1 
ATOM   8605 N N   . LYS E 5 29  ? 132.822 143.759 212.941 1.00 94.68  ? 29  LYS C N   1 
ATOM   8606 C CA  . LYS E 5 29  ? 131.781 143.456 211.970 1.00 94.47  ? 29  LYS C CA  1 
ATOM   8607 C C   . LYS E 5 29  ? 132.052 144.167 210.649 1.00 95.73  ? 29  LYS C C   1 
ATOM   8608 O O   . LYS E 5 29  ? 132.567 145.288 210.612 1.00 98.67  ? 29  LYS C O   1 
ATOM   8609 C CB  . LYS E 5 29  ? 130.410 143.863 212.510 1.00 90.99  ? 29  LYS C CB  1 
ATOM   8610 C CG  . LYS E 5 29  ? 130.083 143.293 213.880 1.00 91.14  ? 29  LYS C CG  1 
ATOM   8611 C CD  . LYS E 5 29  ? 130.048 141.776 213.857 1.00 93.59  ? 29  LYS C CD  1 
ATOM   8612 C CE  . LYS E 5 29  ? 128.894 141.262 213.013 1.00 94.65  ? 29  LYS C CE  1 
ATOM   8613 N NZ  . LYS E 5 29  ? 128.795 139.777 213.054 1.00 96.21  ? 29  LYS C NZ  1 
ATOM   8614 N N   . VAL E 5 30  ? 131.700 143.494 209.552 1.00 86.42  ? 30  VAL C N   1 
ATOM   8615 C CA  . VAL E 5 30  ? 131.925 144.057 208.224 1.00 82.88  ? 30  VAL C CA  1 
ATOM   8616 C C   . VAL E 5 30  ? 131.043 145.279 208.001 1.00 86.31  ? 30  VAL C C   1 
ATOM   8617 O O   . VAL E 5 30  ? 131.457 146.251 207.356 1.00 91.22  ? 30  VAL C O   1 
ATOM   8618 C CB  . VAL E 5 30  ? 131.695 142.976 207.151 1.00 84.04  ? 30  VAL C CB  1 
ATOM   8619 C CG1 . VAL E 5 30  ? 131.310 143.599 205.819 1.00 86.57  ? 30  VAL C CG1 1 
ATOM   8620 C CG2 . VAL E 5 30  ? 132.939 142.126 206.994 1.00 82.27  ? 30  VAL C CG2 1 
ATOM   8621 N N   . SER E 5 31  ? 129.821 145.256 208.538 1.00 77.70  ? 31  SER C N   1 
ATOM   8622 C CA  . SER E 5 31  ? 128.900 146.369 208.334 1.00 78.48  ? 31  SER C CA  1 
ATOM   8623 C C   . SER E 5 31  ? 129.458 147.667 208.904 1.00 82.49  ? 31  SER C C   1 
ATOM   8624 O O   . SER E 5 31  ? 129.287 148.738 208.309 1.00 87.75  ? 31  SER C O   1 
ATOM   8625 C CB  . SER E 5 31  ? 127.544 146.049 208.961 1.00 80.33  ? 31  SER C CB  1 
ATOM   8626 O OG  . SER E 5 31  ? 127.638 146.002 210.373 1.00 83.61  ? 31  SER C OG  1 
ATOM   8627 N N   . LYS E 5 32  ? 130.123 147.594 210.059 1.00 85.75  ? 32  LYS C N   1 
ATOM   8628 C CA  . LYS E 5 32  ? 130.712 148.794 210.647 1.00 87.81  ? 32  LYS C CA  1 
ATOM   8629 C C   . LYS E 5 32  ? 131.801 149.375 209.751 1.00 87.29  ? 32  LYS C C   1 
ATOM   8630 O O   . LYS E 5 32  ? 131.867 150.594 209.552 1.00 91.96  ? 32  LYS C O   1 
ATOM   8631 C CB  . LYS E 5 32  ? 131.267 148.478 212.035 1.00 88.47  ? 32  LYS C CB  1 
ATOM   8632 C CG  . LYS E 5 32  ? 131.622 149.704 212.854 1.00 90.67  ? 32  LYS C CG  1 
ATOM   8633 C CD  . LYS E 5 32  ? 131.579 149.401 214.342 1.00 89.35  ? 32  LYS C CD  1 
ATOM   8634 C CE  . LYS E 5 32  ? 132.556 150.275 215.111 1.00 90.09  ? 32  LYS C CE  1 
ATOM   8635 N NZ  . LYS E 5 32  ? 133.951 150.117 214.618 1.00 90.49  ? 32  LYS C NZ  1 
ATOM   8636 N N   . ALA E 5 33  ? 132.662 148.518 209.198 1.00 69.40  ? 33  ALA C N   1 
ATOM   8637 C CA  . ALA E 5 33  ? 133.702 148.998 208.294 1.00 72.23  ? 33  ALA C CA  1 
ATOM   8638 C C   . ALA E 5 33  ? 133.100 149.597 207.030 1.00 79.29  ? 33  ALA C C   1 
ATOM   8639 O O   . ALA E 5 33  ? 133.583 150.618 206.523 1.00 85.72  ? 33  ALA C O   1 
ATOM   8640 C CB  . ALA E 5 33  ? 134.662 147.863 207.947 1.00 70.11  ? 33  ALA C CB  1 
ATOM   8641 N N   . ALA E 5 34  ? 132.050 148.968 206.502 1.00 76.95  ? 34  ALA C N   1 
ATOM   8642 C CA  . ALA E 5 34  ? 131.376 149.507 205.327 1.00 79.88  ? 34  ALA C CA  1 
ATOM   8643 C C   . ALA E 5 34  ? 130.787 150.882 205.612 1.00 78.92  ? 34  ALA C C   1 
ATOM   8644 O O   . ALA E 5 34  ? 130.905 151.803 204.793 1.00 83.34  ? 34  ALA C O   1 
ATOM   8645 C CB  . ALA E 5 34  ? 130.287 148.542 204.866 1.00 79.49  ? 34  ALA C CB  1 
ATOM   8646 N N   . ALA E 5 35  ? 130.148 151.039 206.773 1.00 77.91  ? 35  ALA C N   1 
ATOM   8647 C CA  . ALA E 5 35  ? 129.589 152.334 207.141 1.00 80.69  ? 35  ALA C CA  1 
ATOM   8648 C C   . ALA E 5 35  ? 130.684 153.378 207.306 1.00 82.37  ? 35  ALA C C   1 
ATOM   8649 O O   . ALA E 5 35  ? 130.505 154.540 206.926 1.00 87.85  ? 35  ALA C O   1 
ATOM   8650 C CB  . ALA E 5 35  ? 128.765 152.208 208.421 1.00 80.55  ? 35  ALA C CB  1 
ATOM   8651 N N   . ASP E 5 36  ? 131.824 152.986 207.882 1.00 82.32  ? 36  ASP C N   1 
ATOM   8652 C CA  . ASP E 5 36  ? 132.934 153.923 208.026 1.00 86.47  ? 36  ASP C CA  1 
ATOM   8653 C C   . ASP E 5 36  ? 133.457 154.373 206.666 1.00 88.28  ? 36  ASP C C   1 
ATOM   8654 O O   . ASP E 5 36  ? 133.738 155.562 206.460 1.00 93.70  ? 36  ASP C O   1 
ATOM   8655 C CB  . ASP E 5 36  ? 134.053 153.288 208.850 1.00 90.55  ? 36  ASP C CB  1 
ATOM   8656 C CG  . ASP E 5 36  ? 134.895 154.315 209.580 1.00 94.33  ? 36  ASP C CG  1 
ATOM   8657 O OD1 . ASP E 5 36  ? 134.908 155.489 209.152 1.00 93.33  ? 36  ASP C OD1 1 
ATOM   8658 O OD2 . ASP E 5 36  ? 135.544 153.949 210.581 1.00 94.21  ? 36  ASP C OD2 1 
ATOM   8659 N N   . LEU E 5 37  ? 133.592 153.435 205.725 1.00 73.66  ? 37  LEU C N   1 
ATOM   8660 C CA  . LEU E 5 37  ? 134.033 153.798 204.381 1.00 73.45  ? 37  LEU C CA  1 
ATOM   8661 C C   . LEU E 5 37  ? 133.036 154.734 203.709 1.00 72.09  ? 37  LEU C C   1 
ATOM   8662 O O   . LEU E 5 37  ? 133.429 155.714 203.062 1.00 74.37  ? 37  LEU C O   1 
ATOM   8663 C CB  . LEU E 5 37  ? 134.240 152.541 203.538 1.00 72.55  ? 37  LEU C CB  1 
ATOM   8664 C CG  . LEU E 5 37  ? 135.685 152.149 203.233 1.00 74.75  ? 37  LEU C CG  1 
ATOM   8665 C CD1 . LEU E 5 37  ? 136.398 151.704 204.496 1.00 74.12  ? 37  LEU C CD1 1 
ATOM   8666 C CD2 . LEU E 5 37  ? 135.731 151.059 202.176 1.00 73.86  ? 37  LEU C CD2 1 
ATOM   8667 N N   . MET E 5 38  ? 131.740 154.450 203.857 1.00 79.48  ? 38  MET C N   1 
ATOM   8668 C CA  . MET E 5 38  ? 130.721 155.321 203.279 1.00 79.22  ? 38  MET C CA  1 
ATOM   8669 C C   . MET E 5 38  ? 130.782 156.719 203.881 1.00 81.14  ? 38  MET C C   1 
ATOM   8670 O O   . MET E 5 38  ? 130.670 157.720 203.161 1.00 84.99  ? 38  MET C O   1 
ATOM   8671 C CB  . MET E 5 38  ? 129.337 154.707 203.486 1.00 83.34  ? 38  MET C CB  1 
ATOM   8672 C CG  . MET E 5 38  ? 128.340 155.030 202.391 1.00 88.86  ? 38  MET C CG  1 
ATOM   8673 S SD  . MET E 5 38  ? 126.643 154.672 202.879 1.00 103.68 ? 38  MET C SD  1 
ATOM   8674 C CE  . MET E 5 38  ? 126.183 156.214 203.665 1.00 87.44  ? 38  MET C CE  1 
ATOM   8675 N N   . ALA E 5 39  ? 130.957 156.808 205.201 1.00 77.68  ? 39  ALA C N   1 
ATOM   8676 C CA  . ALA E 5 39  ? 131.036 158.110 205.854 1.00 80.08  ? 39  ALA C CA  1 
ATOM   8677 C C   . ALA E 5 39  ? 132.252 158.895 205.380 1.00 80.08  ? 39  ALA C C   1 
ATOM   8678 O O   . ALA E 5 39  ? 132.158 160.102 205.123 1.00 80.97  ? 39  ALA C O   1 
ATOM   8679 C CB  . ALA E 5 39  ? 131.068 157.935 207.372 1.00 77.39  ? 39  ALA C CB  1 
ATOM   8680 N N   . TYR E 5 40  ? 133.404 158.231 205.256 1.00 70.12  ? 40  TYR C N   1 
ATOM   8681 C CA  . TYR E 5 40  ? 134.589 158.921 204.756 1.00 62.42  ? 40  TYR C CA  1 
ATOM   8682 C C   . TYR E 5 40  ? 134.385 159.395 203.324 1.00 65.62  ? 40  TYR C C   1 
ATOM   8683 O O   . TYR E 5 40  ? 134.810 160.498 202.962 1.00 69.51  ? 40  TYR C O   1 
ATOM   8684 C CB  . TYR E 5 40  ? 135.818 158.018 204.848 1.00 64.92  ? 40  TYR C CB  1 
ATOM   8685 C CG  . TYR E 5 40  ? 137.118 158.722 204.518 1.00 66.23  ? 40  TYR C CG  1 
ATOM   8686 C CD1 . TYR E 5 40  ? 137.539 158.870 203.204 1.00 70.80  ? 40  TYR C CD1 1 
ATOM   8687 C CD2 . TYR E 5 40  ? 137.922 159.241 205.520 1.00 66.17  ? 40  TYR C CD2 1 
ATOM   8688 C CE1 . TYR E 5 40  ? 138.721 159.512 202.900 1.00 70.81  ? 40  TYR C CE1 1 
ATOM   8689 C CE2 . TYR E 5 40  ? 139.106 159.885 205.223 1.00 69.22  ? 40  TYR C CE2 1 
ATOM   8690 C CZ  . TYR E 5 40  ? 139.500 160.018 203.912 1.00 69.54  ? 40  TYR C CZ  1 
ATOM   8691 O OH  . TYR E 5 40  ? 140.678 160.658 203.612 1.00 68.56  ? 40  TYR C OH  1 
ATOM   8692 N N   . CYS E 5 41  ? 133.748 158.571 202.489 1.00 78.42  ? 41  CYS C N   1 
ATOM   8693 C CA  . CYS E 5 41  ? 133.506 158.972 201.107 1.00 76.79  ? 41  CYS C CA  1 
ATOM   8694 C C   . CYS E 5 41  ? 132.570 160.172 201.034 1.00 79.00  ? 41  CYS C C   1 
ATOM   8695 O O   . CYS E 5 41  ? 132.774 161.079 200.218 1.00 76.54  ? 41  CYS C O   1 
ATOM   8696 C CB  . CYS E 5 41  ? 132.937 157.797 200.313 1.00 78.66  ? 41  CYS C CB  1 
ATOM   8697 S SG  . CYS E 5 41  ? 134.174 156.851 199.403 1.00 88.35  ? 41  CYS C SG  1 
ATOM   8698 N N   . GLU E 5 42  ? 131.537 160.197 201.877 1.00 89.74  ? 42  GLU C N   1 
ATOM   8699 C CA  . GLU E 5 42  ? 130.583 161.301 201.845 1.00 83.78  ? 42  GLU C CA  1 
ATOM   8700 C C   . GLU E 5 42  ? 131.139 162.574 202.469 1.00 82.01  ? 42  GLU C C   1 
ATOM   8701 O O   . GLU E 5 42  ? 130.721 163.674 202.091 1.00 86.59  ? 42  GLU C O   1 
ATOM   8702 C CB  . GLU E 5 42  ? 129.287 160.900 202.550 1.00 89.78  ? 42  GLU C CB  1 
ATOM   8703 C CG  . GLU E 5 42  ? 128.556 159.742 201.891 1.00 95.28  ? 42  GLU C CG  1 
ATOM   8704 C CD  . GLU E 5 42  ? 128.547 159.844 200.379 1.00 98.98  ? 42  GLU C CD  1 
ATOM   8705 O OE1 . GLU E 5 42  ? 127.759 160.650 199.841 1.00 97.84  ? 42  GLU C OE1 1 
ATOM   8706 O OE2 . GLU E 5 42  ? 129.329 159.120 199.728 1.00 97.04  ? 42  GLU C OE2 1 
ATOM   8707 N N   . ALA E 5 43  ? 132.070 162.457 203.416 1.00 77.51  ? 43  ALA C N   1 
ATOM   8708 C CA  . ALA E 5 43  ? 132.580 163.627 204.119 1.00 78.00  ? 43  ALA C CA  1 
ATOM   8709 C C   . ALA E 5 43  ? 133.650 164.384 203.343 1.00 76.34  ? 43  ALA C C   1 
ATOM   8710 O O   . ALA E 5 43  ? 134.084 165.446 203.802 1.00 77.36  ? 43  ALA C O   1 
ATOM   8711 C CB  . ALA E 5 43  ? 133.138 163.216 205.484 1.00 78.68  ? 43  ALA C CB  1 
ATOM   8712 N N   . HIS E 5 44  ? 134.091 163.874 202.194 1.00 73.80  ? 44  HIS C N   1 
ATOM   8713 C CA  . HIS E 5 44  ? 135.135 164.521 201.407 1.00 73.00  ? 44  HIS C CA  1 
ATOM   8714 C C   . HIS E 5 44  ? 134.731 164.644 199.942 1.00 74.94  ? 44  HIS C C   1 
ATOM   8715 O O   . HIS E 5 44  ? 135.576 164.548 199.050 1.00 76.04  ? 44  HIS C O   1 
ATOM   8716 C CB  . HIS E 5 44  ? 136.457 163.767 201.530 1.00 74.61  ? 44  HIS C CB  1 
ATOM   8717 C CG  . HIS E 5 44  ? 137.156 163.980 202.835 1.00 75.16  ? 44  HIS C CG  1 
ATOM   8718 N ND1 . HIS E 5 44  ? 138.435 164.485 202.918 1.00 77.89  ? 44  HIS C ND1 1 
ATOM   8719 C CD2 . HIS E 5 44  ? 136.759 163.750 204.108 1.00 76.18  ? 44  HIS C CD2 1 
ATOM   8720 C CE1 . HIS E 5 44  ? 138.794 164.562 204.187 1.00 80.54  ? 44  HIS C CE1 1 
ATOM   8721 N NE2 . HIS E 5 44  ? 137.794 164.122 204.930 1.00 79.16  ? 44  HIS C NE2 1 
ATOM   8722 N N   . ALA E 5 45  ? 133.442 164.861 199.677 1.00 84.88  ? 45  ALA C N   1 
ATOM   8723 C CA  . ALA E 5 45  ? 132.979 164.940 198.296 1.00 87.95  ? 45  ALA C CA  1 
ATOM   8724 C C   . ALA E 5 45  ? 133.376 166.259 197.644 1.00 86.91  ? 45  ALA C C   1 
ATOM   8725 O O   . ALA E 5 45  ? 133.777 166.283 196.475 1.00 87.62  ? 45  ALA C O   1 
ATOM   8726 C CB  . ALA E 5 45  ? 131.464 164.752 198.240 1.00 88.55  ? 45  ALA C CB  1 
ATOM   8727 N N   . LYS E 5 46  ? 133.272 167.366 198.382 1.00 91.53  ? 46  LYS C N   1 
ATOM   8728 C CA  . LYS E 5 46  ? 133.492 168.682 197.793 1.00 91.39  ? 46  LYS C CA  1 
ATOM   8729 C C   . LYS E 5 46  ? 134.948 168.935 197.427 1.00 87.69  ? 46  LYS C C   1 
ATOM   8730 O O   . LYS E 5 46  ? 135.227 169.873 196.675 1.00 88.21  ? 46  LYS C O   1 
ATOM   8731 C CB  . LYS E 5 46  ? 133.006 169.772 198.749 1.00 93.36  ? 46  LYS C CB  1 
ATOM   8732 C CG  . LYS E 5 46  ? 131.838 169.355 199.628 1.00 93.32  ? 46  LYS C CG  1 
ATOM   8733 C CD  . LYS E 5 46  ? 130.550 169.260 198.826 1.00 95.54  ? 46  LYS C CD  1 
ATOM   8734 C CE  . LYS E 5 46  ? 130.150 170.613 198.260 1.00 94.23  ? 46  LYS C CE  1 
ATOM   8735 N NZ  . LYS E 5 46  ? 128.816 170.567 197.600 1.00 92.79  ? 46  LYS C NZ  1 
ATOM   8736 N N   . GLU E 5 47  ? 135.879 168.128 197.934 1.00 89.34  ? 47  GLU C N   1 
ATOM   8737 C CA  . GLU E 5 47  ? 137.302 168.329 197.690 1.00 91.88  ? 47  GLU C CA  1 
ATOM   8738 C C   . GLU E 5 47  ? 137.890 167.252 196.782 1.00 99.91  ? 47  GLU C C   1 
ATOM   8739 O O   . GLU E 5 47  ? 139.073 166.921 196.888 1.00 100.80 ? 47  GLU C O   1 
ATOM   8740 C CB  . GLU E 5 47  ? 138.067 168.391 199.010 1.00 91.84  ? 47  GLU C CB  1 
ATOM   8741 C CG  . GLU E 5 47  ? 137.602 167.386 200.048 1.00 94.75  ? 47  GLU C CG  1 
ATOM   8742 C CD  . GLU E 5 47  ? 138.351 167.516 201.359 1.00 99.46  ? 47  GLU C CD  1 
ATOM   8743 O OE1 . GLU E 5 47  ? 139.531 167.926 201.332 1.00 100.93 ? 47  GLU C OE1 1 
ATOM   8744 O OE2 . GLU E 5 47  ? 137.761 167.211 202.416 1.00 98.86  ? 47  GLU C OE2 1 
ATOM   8745 N N   . ASP E 5 48  ? 137.073 166.687 195.885 1.00 95.35  ? 48  ASP C N   1 
ATOM   8746 C CA  . ASP E 5 48  ? 137.580 165.669 194.921 1.00 89.58  ? 48  ASP C CA  1 
ATOM   8747 C C   . ASP E 5 48  ? 137.420 166.210 193.502 1.00 87.22  ? 48  ASP C C   1 
ATOM   8748 O O   . ASP E 5 48  ? 136.364 165.961 192.892 1.00 91.28  ? 48  ASP C O   1 
ATOM   8749 C CB  . ASP E 5 48  ? 136.866 164.328 195.094 1.00 50.00  ? 48  ASP C CB  1 
ATOM   8750 C CG  . ASP E 5 48  ? 137.416 163.230 194.199 1.00 50.00  ? 48  ASP C CG  1 
ATOM   8751 O OD1 . ASP E 5 48  ? 138.551 163.390 193.705 1.00 50.00  ? 48  ASP C OD1 1 
ATOM   8752 O OD2 . ASP E 5 48  ? 136.707 162.223 194.008 1.00 50.00  ? 48  ASP C OD2 1 
ATOM   8753 N N   . PRO E 5 49  ? 138.417 166.912 192.934 1.00 78.72  ? 49  PRO C N   1 
ATOM   8754 C CA  . PRO E 5 49  ? 138.265 167.565 191.624 1.00 81.42  ? 49  PRO C CA  1 
ATOM   8755 C C   . PRO E 5 49  ? 137.813 166.636 190.511 1.00 78.98  ? 49  PRO C C   1 
ATOM   8756 O O   . PRO E 5 49  ? 137.124 167.087 189.588 1.00 81.12  ? 49  PRO C O   1 
ATOM   8757 C CB  . PRO E 5 49  ? 139.668 168.122 191.354 1.00 80.71  ? 49  PRO C CB  1 
ATOM   8758 C CG  . PRO E 5 49  ? 140.259 168.313 192.705 1.00 79.07  ? 49  PRO C CG  1 
ATOM   8759 C CD  . PRO E 5 49  ? 139.727 167.189 193.543 1.00 79.92  ? 49  PRO C CD  1 
ATOM   8760 N N   . LEU E 5 50  ? 138.183 165.358 190.555 1.00 68.30  ? 50  LEU C N   1 
ATOM   8761 C CA  . LEU E 5 50  ? 137.834 164.456 189.464 1.00 70.28  ? 50  LEU C CA  1 
ATOM   8762 C C   . LEU E 5 50  ? 136.364 164.059 189.485 1.00 76.42  ? 50  LEU C C   1 
ATOM   8763 O O   . LEU E 5 50  ? 135.773 163.842 188.421 1.00 80.93  ? 50  LEU C O   1 
ATOM   8764 C CB  . LEU E 5 50  ? 138.712 163.207 189.514 1.00 70.72  ? 50  LEU C CB  1 
ATOM   8765 C CG  . LEU E 5 50  ? 140.216 163.441 189.408 1.00 70.41  ? 50  LEU C CG  1 
ATOM   8766 C CD1 . LEU E 5 50  ? 140.973 162.184 189.780 1.00 75.07  ? 50  LEU C CD1 1 
ATOM   8767 C CD2 . LEU E 5 50  ? 140.582 163.892 188.008 1.00 71.10  ? 50  LEU C CD2 1 
ATOM   8768 N N   . LEU E 5 51  ? 135.762 163.951 190.671 1.00 82.97  ? 51  LEU C N   1 
ATOM   8769 C CA  . LEU E 5 51  ? 134.367 163.531 190.761 1.00 82.47  ? 51  LEU C CA  1 
ATOM   8770 C C   . LEU E 5 51  ? 133.439 164.542 190.099 1.00 84.98  ? 51  LEU C C   1 
ATOM   8771 O O   . LEU E 5 51  ? 132.600 164.182 189.266 1.00 87.03  ? 51  LEU C O   1 
ATOM   8772 C CB  . LEU E 5 51  ? 133.978 163.328 192.224 1.00 81.69  ? 51  LEU C CB  1 
ATOM   8773 C CG  . LEU E 5 51  ? 133.319 162.001 192.592 1.00 83.19  ? 51  LEU C CG  1 
ATOM   8774 C CD1 . LEU E 5 51  ? 134.116 160.838 192.032 1.00 84.45  ? 51  LEU C CD1 1 
ATOM   8775 C CD2 . LEU E 5 51  ? 133.177 161.886 194.099 1.00 85.60  ? 51  LEU C CD2 1 
ATOM   8776 N N   . THR E 5 52  ? 133.578 165.816 190.457 1.00 97.30  ? 52  THR C N   1 
ATOM   8777 C CA  . THR E 5 52  ? 132.749 166.882 189.927 1.00 97.63  ? 52  THR C CA  1 
ATOM   8778 C C   . THR E 5 52  ? 133.615 167.848 189.131 1.00 99.80  ? 52  THR C C   1 
ATOM   8779 O O   . THR E 5 52  ? 134.661 168.286 189.630 1.00 100.28 ? 52  THR C O   1 
ATOM   8780 C CB  . THR E 5 52  ? 132.033 167.637 191.056 1.00 98.21  ? 52  THR C CB  1 
ATOM   8781 O OG1 . THR E 5 52  ? 132.914 168.625 191.604 1.00 96.80  ? 52  THR C OG1 1 
ATOM   8782 C CG2 . THR E 5 52  ? 131.609 166.676 192.155 1.00 97.68  ? 52  THR C CG2 1 
ATOM   8783 N N   . PRO E 5 53  ? 133.219 168.214 187.910 1.00 113.88 ? 53  PRO C N   1 
ATOM   8784 C CA  . PRO E 5 53  ? 134.090 169.047 187.069 1.00 114.54 ? 53  PRO C CA  1 
ATOM   8785 C C   . PRO E 5 53  ? 134.361 170.419 187.666 1.00 113.91 ? 53  PRO C C   1 
ATOM   8786 O O   . PRO E 5 53  ? 133.454 171.247 187.797 1.00 111.84 ? 53  PRO C O   1 
ATOM   8787 C CB  . PRO E 5 53  ? 133.309 169.154 185.752 1.00 112.67 ? 53  PRO C CB  1 
ATOM   8788 C CG  . PRO E 5 53  ? 131.891 168.866 186.119 1.00 113.30 ? 53  PRO C CG  1 
ATOM   8789 C CD  . PRO E 5 53  ? 131.952 167.877 187.241 1.00 112.32 ? 53  PRO C CD  1 
ATOM   8790 N N   . VAL E 5 54  ? 135.613 170.659 188.033 1.00 114.00 ? 54  VAL C N   1 
ATOM   8791 C CA  . VAL E 5 54  ? 136.012 171.962 188.579 1.00 113.20 ? 54  VAL C CA  1 
ATOM   8792 C C   . VAL E 5 54  ? 135.971 173.001 187.466 1.00 114.79 ? 54  VAL C C   1 
ATOM   8793 O O   . VAL E 5 54  ? 136.431 172.718 186.344 1.00 115.05 ? 54  VAL C O   1 
ATOM   8794 C CB  . VAL E 5 54  ? 137.408 171.868 189.202 1.00 112.13 ? 54  VAL C CB  1 
ATOM   8795 C CG1 . VAL E 5 54  ? 138.092 173.226 189.226 1.00 110.47 ? 54  VAL C CG1 1 
ATOM   8796 C CG2 . VAL E 5 54  ? 137.322 171.286 190.605 1.00 111.41 ? 54  VAL C CG2 1 
ATOM   8797 N N   . PRO E 5 55  ? 135.421 174.192 187.706 1.00 115.67 ? 55  PRO C N   1 
ATOM   8798 C CA  . PRO E 5 55  ? 135.395 175.216 186.654 1.00 114.53 ? 55  PRO C CA  1 
ATOM   8799 C C   . PRO E 5 55  ? 136.801 175.584 186.203 1.00 113.97 ? 55  PRO C C   1 
ATOM   8800 O O   . PRO E 5 55  ? 137.739 175.630 187.001 1.00 112.72 ? 55  PRO C O   1 
ATOM   8801 C CB  . PRO E 5 55  ? 134.686 176.399 187.325 1.00 113.85 ? 55  PRO C CB  1 
ATOM   8802 C CG  . PRO E 5 55  ? 134.793 176.139 188.794 1.00 114.90 ? 55  PRO C CG  1 
ATOM   8803 C CD  . PRO E 5 55  ? 134.774 174.653 188.945 1.00 114.59 ? 55  PRO C CD  1 
ATOM   8804 N N   . ALA E 5 56  ? 136.935 175.855 184.905 1.00 104.99 ? 56  ALA C N   1 
ATOM   8805 C CA  . ALA E 5 56  ? 138.237 176.073 184.284 1.00 103.57 ? 56  ALA C CA  1 
ATOM   8806 C C   . ALA E 5 56  ? 138.920 177.355 184.739 1.00 102.68 ? 56  ALA C C   1 
ATOM   8807 O O   . ALA E 5 56  ? 140.025 177.640 184.265 1.00 101.58 ? 56  ALA C O   1 
ATOM   8808 C CB  . ALA E 5 56  ? 138.094 176.081 182.762 1.00 99.93  ? 56  ALA C CB  1 
ATOM   8809 N N   . SER E 5 57  ? 138.303 178.135 185.628 1.00 102.14 ? 57  SER C N   1 
ATOM   8810 C CA  . SER E 5 57  ? 138.947 179.352 186.109 1.00 102.33 ? 57  SER C CA  1 
ATOM   8811 C C   . SER E 5 57  ? 140.202 179.036 186.912 1.00 102.08 ? 57  SER C C   1 
ATOM   8812 O O   . SER E 5 57  ? 141.232 179.703 186.757 1.00 102.58 ? 57  SER C O   1 
ATOM   8813 C CB  . SER E 5 57  ? 137.964 180.169 186.949 1.00 104.60 ? 57  SER C CB  1 
ATOM   8814 O OG  . SER E 5 57  ? 138.646 181.113 187.757 1.00 107.23 ? 57  SER C OG  1 
ATOM   8815 N N   . GLU E 5 58  ? 140.140 178.019 187.772 1.00 103.79 ? 58  GLU C N   1 
ATOM   8816 C CA  . GLU E 5 58  ? 141.247 177.675 188.655 1.00 105.69 ? 58  GLU C CA  1 
ATOM   8817 C C   . GLU E 5 58  ? 141.887 176.338 188.297 1.00 104.58 ? 58  GLU C C   1 
ATOM   8818 O O   . GLU E 5 58  ? 142.660 175.794 189.090 1.00 104.43 ? 58  GLU C O   1 
ATOM   8819 C CB  . GLU E 5 58  ? 140.779 177.664 190.111 1.00 106.65 ? 58  GLU C CB  1 
ATOM   8820 C CG  . GLU E 5 58  ? 139.809 176.545 190.453 1.00 108.86 ? 58  GLU C CG  1 
ATOM   8821 C CD  . GLU E 5 58  ? 138.371 176.888 190.114 1.00 110.42 ? 58  GLU C CD  1 
ATOM   8822 O OE1 . GLU E 5 58  ? 138.149 177.838 189.334 1.00 106.70 ? 58  GLU C OE1 1 
ATOM   8823 O OE2 . GLU E 5 58  ? 137.462 176.209 190.634 1.00 112.53 ? 58  GLU C OE2 1 
ATOM   8824 N N   . ASN E 5 59  ? 141.586 175.801 187.123 1.00 92.91  ? 59  ASN C N   1 
ATOM   8825 C CA  . ASN E 5 59  ? 142.186 174.542 186.703 1.00 88.62  ? 59  ASN C CA  1 
ATOM   8826 C C   . ASN E 5 59  ? 143.631 174.784 186.288 1.00 87.35  ? 59  ASN C C   1 
ATOM   8827 O O   . ASN E 5 59  ? 143.875 175.558 185.355 1.00 89.70  ? 59  ASN C O   1 
ATOM   8828 C CB  . ASN E 5 59  ? 141.399 173.936 185.550 1.00 88.41  ? 59  ASN C CB  1 
ATOM   8829 C CG  . ASN E 5 59  ? 141.682 172.460 185.362 1.00 88.74  ? 59  ASN C CG  1 
ATOM   8830 O OD1 . ASN E 5 59  ? 142.835 172.030 185.364 1.00 91.52  ? 59  ASN C OD1 1 
ATOM   8831 N ND2 . ASN E 5 59  ? 140.624 171.674 185.199 1.00 90.32  ? 59  ASN C ND2 1 
ATOM   8832 N N   . PRO E 5 60  ? 144.610 174.160 186.947 1.00 80.02  ? 60  PRO C N   1 
ATOM   8833 C CA  . PRO E 5 60  ? 146.011 174.390 186.560 1.00 78.75  ? 60  PRO C CA  1 
ATOM   8834 C C   . PRO E 5 60  ? 146.319 173.977 185.134 1.00 78.49  ? 60  PRO C C   1 
ATOM   8835 O O   . PRO E 5 60  ? 147.149 174.620 184.479 1.00 82.01  ? 60  PRO C O   1 
ATOM   8836 C CB  . PRO E 5 60  ? 146.804 173.553 187.573 1.00 86.56  ? 60  PRO C CB  1 
ATOM   8837 C CG  . PRO E 5 60  ? 145.845 173.206 188.663 1.00 85.73  ? 60  PRO C CG  1 
ATOM   8838 C CD  . PRO E 5 60  ? 144.479 173.220 188.069 1.00 84.91  ? 60  PRO C CD  1 
ATOM   8839 N N   . PHE E 5 61  ? 145.679 172.925 184.632 1.00 78.96  ? 61  PHE C N   1 
ATOM   8840 C CA  . PHE E 5 61  ? 145.890 172.461 183.263 1.00 79.89  ? 61  PHE C CA  1 
ATOM   8841 C C   . PHE E 5 61  ? 144.812 173.083 182.384 1.00 82.40  ? 61  PHE C C   1 
ATOM   8842 O O   . PHE E 5 61  ? 143.618 172.864 182.597 1.00 85.30  ? 61  PHE C O   1 
ATOM   8843 C CB  . PHE E 5 61  ? 145.861 170.938 183.194 1.00 80.13  ? 61  PHE C CB  1 
ATOM   8844 C CG  . PHE E 5 61  ? 146.785 170.267 184.170 1.00 78.49  ? 61  PHE C CG  1 
ATOM   8845 C CD1 . PHE E 5 61  ? 148.112 170.049 183.850 1.00 77.75  ? 61  PHE C CD1 1 
ATOM   8846 C CD2 . PHE E 5 61  ? 146.324 169.846 185.403 1.00 77.76  ? 61  PHE C CD2 1 
ATOM   8847 C CE1 . PHE E 5 61  ? 148.963 169.433 184.745 1.00 79.14  ? 61  PHE C CE1 1 
ATOM   8848 C CE2 . PHE E 5 61  ? 147.171 169.228 186.300 1.00 79.99  ? 61  PHE C CE2 1 
ATOM   8849 C CZ  . PHE E 5 61  ? 148.491 169.020 185.970 1.00 79.38  ? 61  PHE C CZ  1 
ATOM   8850 N N   . ARG E 5 62  ? 145.233 173.864 181.395 1.00 94.28  ? 62  ARG C N   1 
ATOM   8851 C CA  . ARG E 5 62  ? 144.295 174.536 180.505 1.00 95.55  ? 62  ARG C CA  1 
ATOM   8852 C C   . ARG E 5 62  ? 144.857 174.655 179.094 1.00 92.50  ? 62  ARG C C   1 
ATOM   8853 O O   . ARG E 5 62  ? 144.230 175.245 178.214 1.00 93.18  ? 62  ARG C O   1 
ATOM   8854 C CB  . ARG E 5 62  ? 143.946 175.922 181.047 1.00 97.46  ? 62  ARG C CB  1 
ATOM   8855 C CG  . ARG E 5 62  ? 142.639 175.976 181.814 1.00 97.72  ? 62  ARG C CG  1 
ATOM   8856 C CD  . ARG E 5 62  ? 141.986 177.341 181.685 1.00 98.81  ? 62  ARG C CD  1 
ATOM   8857 N NE  . ARG E 5 62  ? 142.952 178.424 181.823 1.00 103.01 ? 62  ARG C NE  1 
ATOM   8858 C CZ  . ARG E 5 62  ? 143.392 178.894 182.982 1.00 101.78 ? 62  ARG C CZ  1 
ATOM   8859 N NH1 . ARG E 5 62  ? 142.967 178.402 184.134 1.00 99.81  ? 62  ARG C NH1 1 
ATOM   8860 N NH2 . ARG E 5 62  ? 144.279 179.885 182.986 1.00 97.87  ? 62  ARG C NH2 1 
HETATM 8861 C C1  . XOT F 6 .   ? 147.321 163.572 123.141 1.00 111.30 ? 401 XOT R C1  1 
HETATM 8862 C C2  . XOT F 6 .   ? 147.940 163.339 124.525 1.00 111.16 ? 401 XOT R C2  1 
HETATM 8863 C C3  . XOT F 6 .   ? 148.957 164.441 124.659 1.00 116.54 ? 401 XOT R C3  1 
HETATM 8864 C C4  . XOT F 6 .   ? 148.853 165.301 123.593 1.00 114.78 ? 401 XOT R C4  1 
HETATM 8865 C C5  . XOT F 6 .   ? 149.960 164.923 125.457 1.00 118.12 ? 401 XOT R C5  1 
HETATM 8866 C C6  . XOT F 6 .   ? 150.486 164.380 126.737 1.00 115.94 ? 401 XOT R C6  1 
HETATM 8867 C C7  . XOT F 6 .   ? 147.798 164.908 122.626 1.00 113.20 ? 401 XOT R C7  1 
HETATM 8868 C C8  . XOT F 6 .   ? 146.360 164.703 122.966 1.00 110.46 ? 401 XOT R C8  1 
HETATM 8869 N N1  . XOT F 6 .   ? 149.776 166.270 123.751 1.00 111.09 ? 401 XOT R N1  1 
HETATM 8870 N N2  . XOT F 6 .   ? 150.460 166.038 124.904 1.00 115.06 ? 401 XOT R N2  1 
HETATM 8871 O O1  . XOT F 6 .   ? 149.975 163.330 127.198 1.00 112.35 ? 401 XOT R O1  1 
HETATM 8872 O O2  . XOT F 6 .   ? 151.424 164.991 127.305 1.00 115.04 ? 401 XOT R O2  1 
# 
