data_8UN2
# 
_entry.id   8UN2 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UN2         pdb_00008un2 10.2210/pdb8un2/pdb 
WWPDB D_1000278426 ?            ?                   
EMDB  EMD-42391    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-23 ? 
2 'EM metadata'     1 0 2025-04-23 ? 
3 FSC               1 0 2025-04-23 ? 
4 'Half map'        1 0 2025-04-23 1 
5 'Half map'        1 0 2025-04-23 2 
6 Image             1 0 2025-04-23 ? 
7 'Primary map'     1 0 2025-04-23 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UN2 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type (cryo-EM)' 
_pdbx_database_related.db_id          EMD-42391 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              divne@kth.se 
_pdbx_contact_author.name_first         Christina 
_pdbx_contact_author.name_last          Divne 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-5805-2693 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Furlanetto, V.' 1 0000-0003-2875-0156 
'Kalyani, D.C.'  2 0000-0001-5829-9357 
'Hallberg, B.M.' 3 0000-0002-6781-0345 
'Divne, C.'      4 0000-0002-5805-2693 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To be published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type (cryo-EM)' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Furlanetto, V.' 1 0000-0003-2875-0156 
primary 'Kalyani, D.C.'  2 0000-0001-5829-9357 
primary 'Srivastava, V.' 3 ?                   
primary 'Hallberg, B.M.' 4 0000-0002-6781-0345 
primary 'Ezcurra, I.'    5 0000-0001-9080-3031 
primary 'Divne, C.'      6 0000-0002-5805-2693 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Sugar phosphate isomerase' 48768.133 2 ? ? ? ? 
2 non-polymer syn 'MANGANESE (II) ION'        54.938    2 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRLAE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRLAE
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'MANGANESE (II) ION' 
_pdbx_entity_nonpoly.comp_id     MN 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LEU n 
1 3   LEU n 
1 4   GLU n 
1 5   ARG n 
1 6   ASP n 
1 7   LEU n 
1 8   ILE n 
1 9   GLN n 
1 10  SER n 
1 11  VAL n 
1 12  GLY n 
1 13  PHE n 
1 14  ARG n 
1 15  ASN n 
1 16  VAL n 
1 17  ARG n 
1 18  GLU n 
1 19  GLY n 
1 20  GLY n 
1 21  GLU n 
1 22  ILE n 
1 23  THR n 
1 24  GLY n 
1 25  PHE n 
1 26  GLN n 
1 27  PHE n 
1 28  ARG n 
1 29  VAL n 
1 30  ARG n 
1 31  MET n 
1 32  PRO n 
1 33  SER n 
1 34  TYR n 
1 35  ARG n 
1 36  GLY n 
1 37  MET n 
1 38  ALA n 
1 39  ALA n 
1 40  SER n 
1 41  LEU n 
1 42  ILE n 
1 43  ASP n 
1 44  GLY n 
1 45  ILE n 
1 46  GLY n 
1 47  VAL n 
1 48  ARG n 
1 49  ILE n 
1 50  PRO n 
1 51  GLY n 
1 52  LEU n 
1 53  VAL n 
1 54  ASP n 
1 55  VAL n 
1 56  GLY n 
1 57  PRO n 
1 58  ASP n 
1 59  VAL n 
1 60  PRO n 
1 61  LEU n 
1 62  TRP n 
1 63  THR n 
1 64  LEU n 
1 65  GLN n 
1 66  GLY n 
1 67  GLN n 
1 68  GLN n 
1 69  TYR n 
1 70  THR n 
1 71  LEU n 
1 72  ALA n 
1 73  GLU n 
1 74  LEU n 
1 75  TRP n 
1 76  ASP n 
1 77  GLY n 
1 78  ASP n 
1 79  GLY n 
1 80  VAL n 
1 81  ARG n 
1 82  TRP n 
1 83  PRO n 
1 84  LEU n 
1 85  GLU n 
1 86  ASP n 
1 87  ALA n 
1 88  ALA n 
1 89  ILE n 
1 90  ILE n 
1 91  PHE n 
1 92  VAL n 
1 93  PRO n 
1 94  LEU n 
1 95  PRO n 
1 96  GLY n 
1 97  GLY n 
1 98  LEU n 
1 99  PRO n 
1 100 ASP n 
1 101 GLY n 
1 102 VAL n 
1 103 HIS n 
1 104 GLU n 
1 105 LEU n 
1 106 SER n 
1 107 ILE n 
1 108 GLU n 
1 109 LEU n 
1 110 ARG n 
1 111 LEU n 
1 112 ARG n 
1 113 MET n 
1 114 SER n 
1 115 TYR n 
1 116 ILE n 
1 117 PRO n 
1 118 GLN n 
1 119 GLU n 
1 120 HIS n 
1 121 GLN n 
1 122 PRO n 
1 123 SER n 
1 124 THR n 
1 125 TYR n 
1 126 ARG n 
1 127 VAL n 
1 128 THR n 
1 129 LYS n 
1 130 HIS n 
1 131 VAL n 
1 132 THR n 
1 133 LEU n 
1 134 ALA n 
1 135 PRO n 
1 136 GLU n 
1 137 ALA n 
1 138 SER n 
1 139 GLY n 
1 140 ALA n 
1 141 PRO n 
1 142 PHE n 
1 143 ARG n 
1 144 TYR n 
1 145 GLY n 
1 146 VAL n 
1 147 SER n 
1 148 LEU n 
1 149 TYR n 
1 150 SER n 
1 151 TYR n 
1 152 MET n 
1 153 SER n 
1 154 ASP n 
1 155 TYR n 
1 156 GLY n 
1 157 THR n 
1 158 VAL n 
1 159 MET n 
1 160 ASP n 
1 161 LEU n 
1 162 GLU n 
1 163 THR n 
1 164 ALA n 
1 165 MET n 
1 166 ALA n 
1 167 SER n 
1 168 ILE n 
1 169 ALA n 
1 170 ASP n 
1 171 LEU n 
1 172 GLY n 
1 173 ALA n 
1 174 THR n 
1 175 GLY n 
1 176 ILE n 
1 177 GLU n 
1 178 ILE n 
1 179 LEU n 
1 180 GLY n 
1 181 GLU n 
1 182 ALA n 
1 183 HIS n 
1 184 VAL n 
1 185 PRO n 
1 186 ASN n 
1 187 TYR n 
1 188 PRO n 
1 189 ASN n 
1 190 PRO n 
1 191 SER n 
1 192 ASP n 
1 193 GLU n 
1 194 TRP n 
1 195 VAL n 
1 196 GLU n 
1 197 GLN n 
1 198 TRP n 
1 199 PHE n 
1 200 ALA n 
1 201 LEU n 
1 202 LEU n 
1 203 SER n 
1 204 THR n 
1 205 TYR n 
1 206 GLY n 
1 207 LEU n 
1 208 GLU n 
1 209 PRO n 
1 210 THR n 
1 211 ASN n 
1 212 MET n 
1 213 GLY n 
1 214 SER n 
1 215 TRP n 
1 216 ILE n 
1 217 ASP n 
1 218 THR n 
1 219 ARG n 
1 220 LEU n 
1 221 HIS n 
1 222 SER n 
1 223 SER n 
1 224 GLY n 
1 225 PRO n 
1 226 ASN n 
1 227 GLY n 
1 228 ARG n 
1 229 ASP n 
1 230 MET n 
1 231 THR n 
1 232 VAL n 
1 233 GLU n 
1 234 GLU n 
1 235 GLY n 
1 236 ALA n 
1 237 ALA n 
1 238 ALA n 
1 239 LEU n 
1 240 GLN n 
1 241 ARG n 
1 242 ASP n 
1 243 LEU n 
1 244 ARG n 
1 245 LEU n 
1 246 ALA n 
1 247 LYS n 
1 248 ARG n 
1 249 LEU n 
1 250 GLY n 
1 251 PHE n 
1 252 ARG n 
1 253 PHE n 
1 254 VAL n 
1 255 ARG n 
1 256 PRO n 
1 257 LYS n 
1 258 ILE n 
1 259 GLY n 
1 260 VAL n 
1 261 VAL n 
1 262 SER n 
1 263 SER n 
1 264 ASP n 
1 265 LEU n 
1 266 ILE n 
1 267 PRO n 
1 268 HIS n 
1 269 PRO n 
1 270 ILE n 
1 271 TRP n 
1 272 THR n 
1 273 GLU n 
1 274 VAL n 
1 275 VAL n 
1 276 GLU n 
1 277 ALA n 
1 278 SER n 
1 279 LEU n 
1 280 PRO n 
1 281 LEU n 
1 282 ALA n 
1 283 GLU n 
1 284 GLU n 
1 285 LEU n 
1 286 ASP n 
1 287 VAL n 
1 288 ILE n 
1 289 ILE n 
1 290 CYS n 
1 291 PRO n 
1 292 GLU n 
1 293 ILE n 
1 294 HIS n 
1 295 SER n 
1 296 PRO n 
1 297 THR n 
1 298 PRO n 
1 299 ILE n 
1 300 LYS n 
1 301 HIS n 
1 302 GLU n 
1 303 VAL n 
1 304 VAL n 
1 305 ASP n 
1 306 ASP n 
1 307 TYR n 
1 308 ILE n 
1 309 ALA n 
1 310 LEU n 
1 311 ILE n 
1 312 ARG n 
1 313 ARG n 
1 314 THR n 
1 315 GLY n 
1 316 THR n 
1 317 LYS n 
1 318 HIS n 
1 319 PHE n 
1 320 GLY n 
1 321 LEU n 
1 322 LEU n 
1 323 LEU n 
1 324 ASP n 
1 325 THR n 
1 326 GLY n 
1 327 ILE n 
1 328 PHE n 
1 329 GLN n 
1 330 ASP n 
1 331 ARG n 
1 332 PRO n 
1 333 ILE n 
1 334 PRO n 
1 335 LEU n 
1 336 LYS n 
1 337 PRO n 
1 338 GLY n 
1 339 GLU n 
1 340 LEU n 
1 341 PRO n 
1 342 GLY n 
1 343 GLN n 
1 344 ARG n 
1 345 PRO n 
1 346 ALA n 
1 347 PHE n 
1 348 LEU n 
1 349 ASP n 
1 350 GLY n 
1 351 ILE n 
1 352 HIS n 
1 353 VAL n 
1 354 ASP n 
1 355 PRO n 
1 356 ASN n 
1 357 ASP n 
1 358 VAL n 
1 359 PHE n 
1 360 ASP n 
1 361 VAL n 
1 362 ILE n 
1 363 GLU n 
1 364 ASN n 
1 365 VAL n 
1 366 VAL n 
1 367 PHE n 
1 368 ILE n 
1 369 GLN n 
1 370 ALA n 
1 371 LYS n 
1 372 PHE n 
1 373 HIS n 
1 374 ASP n 
1 375 ILE n 
1 376 ASP n 
1 377 GLU n 
1 378 GLU n 
1 379 LEU n 
1 380 ASP n 
1 381 ASP n 
1 382 LYS n 
1 383 GLN n 
1 384 ILE n 
1 385 PRO n 
1 386 TRP n 
1 387 GLU n 
1 388 PRO n 
1 389 VAL n 
1 390 LEU n 
1 391 LYS n 
1 392 ALA n 
1 393 LEU n 
1 394 LYS n 
1 395 ASP n 
1 396 ALA n 
1 397 GLY n 
1 398 TYR n 
1 399 THR n 
1 400 GLY n 
1 401 TYR n 
1 402 LEU n 
1 403 SER n 
1 404 SER n 
1 405 GLU n 
1 406 TYR n 
1 407 GLU n 
1 408 GLY n 
1 409 GLU n 
1 410 ARG n 
1 411 GLU n 
1 412 PRO n 
1 413 TRP n 
1 414 ARG n 
1 415 SER n 
1 416 ILE n 
1 417 GLU n 
1 418 GLN n 
1 419 VAL n 
1 420 ARG n 
1 421 ARG n 
1 422 GLN n 
1 423 HIS n 
1 424 SER n 
1 425 LEU n 
1 426 ILE n 
1 427 ARG n 
1 428 GLN n 
1 429 ILE n 
1 430 ALA n 
1 431 ASP n 
1 432 ARG n 
1 433 LEU n 
1 434 ALA n 
1 435 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   435 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 NS220_14145 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    NS220 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Microbacterium testaceum' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2033 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli B' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     37762 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               '(DE3)-T1' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          Plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pNIC-CTHO 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE              ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE             ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE           ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'      ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE             ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE            ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'      ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE              ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE            ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE           ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE              ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE               ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE           ? 'C5 H11 N O2 S'  149.211 
MN  non-polymer         . 'MANGANESE (II) ION' ? 'Mn 2'           54.938  
PHE 'L-peptide linking' y PHENYLALANINE        ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE              ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE               ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE            ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN           ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE             ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE               ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   LEU 2   2   2   LEU LEU A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   ARG 5   5   5   ARG ARG A . n 
A 1 6   ASP 6   6   6   ASP ASP A . n 
A 1 7   LEU 7   7   7   LEU LEU A . n 
A 1 8   ILE 8   8   8   ILE ILE A . n 
A 1 9   GLN 9   9   9   GLN GLN A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  VAL 11  11  11  VAL VAL A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  PHE 13  13  13  PHE PHE A . n 
A 1 14  ARG 14  14  14  ARG ARG A . n 
A 1 15  ASN 15  15  15  ASN ASN A . n 
A 1 16  VAL 16  16  16  VAL VAL A . n 
A 1 17  ARG 17  17  17  ARG ARG A . n 
A 1 18  GLU 18  18  18  GLU GLU A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  GLU 21  21  21  GLU GLU A . n 
A 1 22  ILE 22  22  22  ILE ILE A . n 
A 1 23  THR 23  23  23  THR THR A . n 
A 1 24  GLY 24  24  24  GLY GLY A . n 
A 1 25  PHE 25  25  25  PHE PHE A . n 
A 1 26  GLN 26  26  26  GLN GLN A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  VAL 29  29  29  VAL VAL A . n 
A 1 30  ARG 30  30  30  ARG ARG A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  PRO 32  32  32  PRO PRO A . n 
A 1 33  SER 33  33  33  SER SER A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  ARG 35  35  35  ARG ARG A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  MET 37  37  37  MET MET A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  ALA 39  39  39  ALA ALA A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  ASP 43  43  43  ASP ASP A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  ILE 45  45  45  ILE ILE A . n 
A 1 46  GLY 46  46  46  GLY GLY A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  ARG 48  48  48  ARG ARG A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  PRO 50  50  50  PRO PRO A . n 
A 1 51  GLY 51  51  51  GLY GLY A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  VAL 53  53  53  VAL VAL A . n 
A 1 54  ASP 54  54  54  ASP ASP A . n 
A 1 55  VAL 55  55  55  VAL VAL A . n 
A 1 56  GLY 56  56  56  GLY GLY A . n 
A 1 57  PRO 57  57  57  PRO PRO A . n 
A 1 58  ASP 58  58  58  ASP ASP A . n 
A 1 59  VAL 59  59  59  VAL VAL A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  LEU 61  61  61  LEU LEU A . n 
A 1 62  TRP 62  62  62  TRP TRP A . n 
A 1 63  THR 63  63  63  THR THR A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  GLN 65  65  65  GLN GLN A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  GLN 67  67  67  GLN GLN A . n 
A 1 68  GLN 68  68  68  GLN GLN A . n 
A 1 69  TYR 69  69  69  TYR TYR A . n 
A 1 70  THR 70  70  70  THR THR A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  LEU 74  74  74  LEU LEU A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  ASP 76  76  76  ASP ASP A . n 
A 1 77  GLY 77  77  77  GLY GLY A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  ARG 81  81  81  ARG ARG A . n 
A 1 82  TRP 82  82  82  TRP TRP A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  LEU 84  84  84  LEU LEU A . n 
A 1 85  GLU 85  85  85  GLU GLU A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  ILE 90  90  90  ILE ILE A . n 
A 1 91  PHE 91  91  91  PHE PHE A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  PRO 93  93  93  PRO PRO A . n 
A 1 94  LEU 94  94  94  LEU LEU A . n 
A 1 95  PRO 95  95  95  PRO PRO A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  GLY 97  97  97  GLY GLY A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 ASP 100 100 100 ASP ASP A . n 
A 1 101 GLY 101 101 101 GLY GLY A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 HIS 103 103 103 HIS HIS A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 LEU 105 105 105 LEU LEU A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 GLU 108 108 108 GLU GLU A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ARG 110 110 110 ARG ARG A . n 
A 1 111 LEU 111 111 111 LEU LEU A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 MET 113 113 113 MET MET A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 TYR 115 115 115 TYR TYR A . n 
A 1 116 ILE 116 116 116 ILE ILE A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 GLN 118 118 118 GLN GLN A . n 
A 1 119 GLU 119 119 119 GLU GLU A . n 
A 1 120 HIS 120 120 120 HIS HIS A . n 
A 1 121 GLN 121 121 121 GLN GLN A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 ARG 126 126 126 ARG ARG A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 THR 128 128 128 THR THR A . n 
A 1 129 LYS 129 129 129 LYS LYS A . n 
A 1 130 HIS 130 130 130 HIS HIS A . n 
A 1 131 VAL 131 131 131 VAL VAL A . n 
A 1 132 THR 132 132 132 THR THR A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 ALA 137 137 137 ALA ALA A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 GLY 139 139 139 GLY GLY A . n 
A 1 140 ALA 140 140 140 ALA ALA A . n 
A 1 141 PRO 141 141 141 PRO PRO A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 TYR 144 144 144 TYR TYR A . n 
A 1 145 GLY 145 145 145 GLY GLY A . n 
A 1 146 VAL 146 146 146 VAL VAL A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 TYR 149 149 149 TYR TYR A . n 
A 1 150 SER 150 150 150 SER SER A . n 
A 1 151 TYR 151 151 151 TYR TYR A . n 
A 1 152 MET 152 152 152 MET MET A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 ASP 154 154 154 ASP ASP A . n 
A 1 155 TYR 155 155 155 TYR TYR A . n 
A 1 156 GLY 156 156 156 GLY GLY A . n 
A 1 157 THR 157 157 157 THR THR A . n 
A 1 158 VAL 158 158 158 VAL VAL A . n 
A 1 159 MET 159 159 159 MET MET A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 LEU 161 161 161 LEU LEU A . n 
A 1 162 GLU 162 162 162 GLU GLU A . n 
A 1 163 THR 163 163 163 THR THR A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 MET 165 165 165 MET MET A . n 
A 1 166 ALA 166 166 166 ALA ALA A . n 
A 1 167 SER 167 167 167 SER SER A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 ASP 170 170 170 ASP ASP A . n 
A 1 171 LEU 171 171 171 LEU LEU A . n 
A 1 172 GLY 172 172 172 GLY GLY A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 GLY 175 175 175 GLY GLY A . n 
A 1 176 ILE 176 176 176 ILE ILE A . n 
A 1 177 GLU 177 177 177 GLU GLU A . n 
A 1 178 ILE 178 178 178 ILE ILE A . n 
A 1 179 LEU 179 179 179 LEU LEU A . n 
A 1 180 GLY 180 180 180 GLY GLY A . n 
A 1 181 GLU 181 181 181 GLU GLU A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 HIS 183 183 183 HIS HIS A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 PRO 185 185 185 PRO PRO A . n 
A 1 186 ASN 186 186 186 ASN ASN A . n 
A 1 187 TYR 187 187 187 TYR TYR A . n 
A 1 188 PRO 188 188 188 PRO PRO A . n 
A 1 189 ASN 189 189 189 ASN ASN A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 SER 191 191 191 SER SER A . n 
A 1 192 ASP 192 192 192 ASP ASP A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 TRP 194 194 194 TRP TRP A . n 
A 1 195 VAL 195 195 195 VAL VAL A . n 
A 1 196 GLU 196 196 196 GLU GLU A . n 
A 1 197 GLN 197 197 197 GLN GLN A . n 
A 1 198 TRP 198 198 198 TRP TRP A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 LEU 201 201 201 LEU LEU A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 THR 204 204 204 THR THR A . n 
A 1 205 TYR 205 205 205 TYR TYR A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 GLU 208 208 208 GLU GLU A . n 
A 1 209 PRO 209 209 209 PRO PRO A . n 
A 1 210 THR 210 210 210 THR THR A . n 
A 1 211 ASN 211 211 211 ASN ASN A . n 
A 1 212 MET 212 212 212 MET MET A . n 
A 1 213 GLY 213 213 213 GLY GLY A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 TRP 215 215 215 TRP TRP A . n 
A 1 216 ILE 216 216 216 ILE ILE A . n 
A 1 217 ASP 217 217 217 ASP ASP A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 ARG 219 219 219 ARG ARG A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 HIS 221 221 221 HIS HIS A . n 
A 1 222 SER 222 222 222 SER SER A . n 
A 1 223 SER 223 223 223 SER SER A . n 
A 1 224 GLY 224 224 224 GLY GLY A . n 
A 1 225 PRO 225 225 225 PRO PRO A . n 
A 1 226 ASN 226 226 226 ASN ASN A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 ARG 228 228 228 ARG ARG A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 MET 230 230 230 MET MET A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 GLU 233 233 233 GLU GLU A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 GLY 235 235 235 GLY GLY A . n 
A 1 236 ALA 236 236 236 ALA ALA A . n 
A 1 237 ALA 237 237 237 ALA ALA A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 LEU 239 239 239 LEU LEU A . n 
A 1 240 GLN 240 240 240 GLN GLN A . n 
A 1 241 ARG 241 241 241 ARG ARG A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 ARG 244 244 244 ARG ARG A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 ARG 248 248 248 ARG ARG A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 ARG 252 252 252 ARG ARG A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 VAL 254 254 254 VAL VAL A . n 
A 1 255 ARG 255 255 255 ARG ARG A . n 
A 1 256 PRO 256 256 256 PRO PRO A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 ILE 258 258 258 ILE ILE A . n 
A 1 259 GLY 259 259 259 GLY GLY A . n 
A 1 260 VAL 260 260 260 VAL VAL A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 SER 262 262 262 SER SER A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ASP 264 264 264 ASP ASP A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 ILE 266 266 266 ILE ILE A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 HIS 268 268 268 HIS HIS A . n 
A 1 269 PRO 269 269 269 PRO PRO A . n 
A 1 270 ILE 270 270 270 ILE ILE A . n 
A 1 271 TRP 271 271 271 TRP TRP A . n 
A 1 272 THR 272 272 272 THR THR A . n 
A 1 273 GLU 273 273 273 GLU GLU A . n 
A 1 274 VAL 274 274 274 VAL VAL A . n 
A 1 275 VAL 275 275 275 VAL VAL A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 LEU 279 279 279 LEU LEU A . n 
A 1 280 PRO 280 280 280 PRO PRO A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 ALA 282 282 282 ALA ALA A . n 
A 1 283 GLU 283 283 283 GLU GLU A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 ASP 286 286 286 ASP ASP A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ILE 288 288 288 ILE ILE A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 CYS 290 290 290 CYS CYS A . n 
A 1 291 PRO 291 291 291 PRO PRO A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ILE 293 293 293 ILE ILE A . n 
A 1 294 HIS 294 294 294 HIS HIS A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 PRO 296 296 296 PRO PRO A . n 
A 1 297 THR 297 297 297 THR THR A . n 
A 1 298 PRO 298 298 298 PRO PRO A . n 
A 1 299 ILE 299 299 299 ILE ILE A . n 
A 1 300 LYS 300 300 300 LYS LYS A . n 
A 1 301 HIS 301 301 301 HIS HIS A . n 
A 1 302 GLU 302 302 302 GLU GLU A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 ASP 305 305 305 ASP ASP A . n 
A 1 306 ASP 306 306 306 ASP ASP A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 ILE 308 308 308 ILE ILE A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ILE 311 311 311 ILE ILE A . n 
A 1 312 ARG 312 312 312 ARG ARG A . n 
A 1 313 ARG 313 313 313 ARG ARG A . n 
A 1 314 THR 314 314 314 THR THR A . n 
A 1 315 GLY 315 315 315 GLY GLY A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 HIS 318 318 318 HIS HIS A . n 
A 1 319 PHE 319 319 319 PHE PHE A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 LEU 323 323 323 LEU LEU A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 THR 325 325 325 THR THR A . n 
A 1 326 GLY 326 326 326 GLY GLY A . n 
A 1 327 ILE 327 327 327 ILE ILE A . n 
A 1 328 PHE 328 328 328 PHE PHE A . n 
A 1 329 GLN 329 329 329 GLN GLN A . n 
A 1 330 ASP 330 330 330 ASP ASP A . n 
A 1 331 ARG 331 331 331 ARG ARG A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 ILE 333 333 333 ILE ILE A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 LEU 335 335 335 LEU LEU A . n 
A 1 336 LYS 336 336 336 LYS LYS A . n 
A 1 337 PRO 337 337 337 PRO PRO A . n 
A 1 338 GLY 338 338 338 GLY GLY A . n 
A 1 339 GLU 339 339 339 GLU GLU A . n 
A 1 340 LEU 340 340 340 LEU LEU A . n 
A 1 341 PRO 341 341 341 PRO PRO A . n 
A 1 342 GLY 342 342 342 GLY GLY A . n 
A 1 343 GLN 343 343 343 GLN GLN A . n 
A 1 344 ARG 344 344 344 ARG ARG A . n 
A 1 345 PRO 345 345 345 PRO PRO A . n 
A 1 346 ALA 346 346 346 ALA ALA A . n 
A 1 347 PHE 347 347 347 PHE PHE A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 GLY 350 350 350 GLY GLY A . n 
A 1 351 ILE 351 351 351 ILE ILE A . n 
A 1 352 HIS 352 352 352 HIS HIS A . n 
A 1 353 VAL 353 353 353 VAL VAL A . n 
A 1 354 ASP 354 354 354 ASP ASP A . n 
A 1 355 PRO 355 355 355 PRO PRO A . n 
A 1 356 ASN 356 356 356 ASN ASN A . n 
A 1 357 ASP 357 357 357 ASP ASP A . n 
A 1 358 VAL 358 358 358 VAL VAL A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 ASP 360 360 360 ASP ASP A . n 
A 1 361 VAL 361 361 361 VAL VAL A . n 
A 1 362 ILE 362 362 362 ILE ILE A . n 
A 1 363 GLU 363 363 363 GLU GLU A . n 
A 1 364 ASN 364 364 364 ASN ASN A . n 
A 1 365 VAL 365 365 365 VAL VAL A . n 
A 1 366 VAL 366 366 366 VAL VAL A . n 
A 1 367 PHE 367 367 367 PHE PHE A . n 
A 1 368 ILE 368 368 368 ILE ILE A . n 
A 1 369 GLN 369 369 369 GLN GLN A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 LYS 371 371 371 LYS LYS A . n 
A 1 372 PHE 372 372 372 PHE PHE A . n 
A 1 373 HIS 373 373 373 HIS HIS A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 ILE 375 375 375 ILE ILE A . n 
A 1 376 ASP 376 376 376 ASP ASP A . n 
A 1 377 GLU 377 377 377 GLU GLU A . n 
A 1 378 GLU 378 378 378 GLU GLU A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ASP 380 380 380 ASP ASP A . n 
A 1 381 ASP 381 381 381 ASP ASP A . n 
A 1 382 LYS 382 382 382 LYS LYS A . n 
A 1 383 GLN 383 383 383 GLN GLN A . n 
A 1 384 ILE 384 384 384 ILE ILE A . n 
A 1 385 PRO 385 385 385 PRO PRO A . n 
A 1 386 TRP 386 386 386 TRP TRP A . n 
A 1 387 GLU 387 387 387 GLU GLU A . n 
A 1 388 PRO 388 388 388 PRO PRO A . n 
A 1 389 VAL 389 389 389 VAL VAL A . n 
A 1 390 LEU 390 390 390 LEU LEU A . n 
A 1 391 LYS 391 391 391 LYS LYS A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 LEU 393 393 393 LEU LEU A . n 
A 1 394 LYS 394 394 394 LYS LYS A . n 
A 1 395 ASP 395 395 395 ASP ASP A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 GLY 397 397 397 GLY GLY A . n 
A 1 398 TYR 398 398 398 TYR TYR A . n 
A 1 399 THR 399 399 399 THR THR A . n 
A 1 400 GLY 400 400 400 GLY GLY A . n 
A 1 401 TYR 401 401 401 TYR TYR A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 SER 403 403 403 SER SER A . n 
A 1 404 SER 404 404 404 SER SER A . n 
A 1 405 GLU 405 405 405 GLU GLU A . n 
A 1 406 TYR 406 406 406 TYR TYR A . n 
A 1 407 GLU 407 407 407 GLU GLU A . n 
A 1 408 GLY 408 408 408 GLY GLY A . n 
A 1 409 GLU 409 409 409 GLU GLU A . n 
A 1 410 ARG 410 410 410 ARG ARG A . n 
A 1 411 GLU 411 411 411 GLU GLU A . n 
A 1 412 PRO 412 412 412 PRO PRO A . n 
A 1 413 TRP 413 413 413 TRP TRP A . n 
A 1 414 ARG 414 414 414 ARG ARG A . n 
A 1 415 SER 415 415 415 SER SER A . n 
A 1 416 ILE 416 416 416 ILE ILE A . n 
A 1 417 GLU 417 417 417 GLU GLU A . n 
A 1 418 GLN 418 418 418 GLN GLN A . n 
A 1 419 VAL 419 419 419 VAL VAL A . n 
A 1 420 ARG 420 420 420 ARG ARG A . n 
A 1 421 ARG 421 421 421 ARG ARG A . n 
A 1 422 GLN 422 422 422 GLN GLN A . n 
A 1 423 HIS 423 423 423 HIS HIS A . n 
A 1 424 SER 424 424 424 SER SER A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 ILE 426 426 426 ILE ILE A . n 
A 1 427 ARG 427 427 427 ARG ARG A . n 
A 1 428 GLN 428 428 428 GLN GLN A . n 
A 1 429 ILE 429 429 429 ILE ILE A . n 
A 1 430 ALA 430 430 430 ALA ALA A . n 
A 1 431 ASP 431 431 431 ASP ASP A . n 
A 1 432 ARG 432 432 432 ARG ARG A . n 
A 1 433 LEU 433 433 433 LEU LEU A . n 
A 1 434 ALA 434 434 ?   ?   ?   A . n 
A 1 435 GLU 435 435 ?   ?   ?   A . n 
B 1 1   MET 1   1   1   MET MET B . n 
B 1 2   LEU 2   2   2   LEU LEU B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   GLU 4   4   4   GLU GLU B . n 
B 1 5   ARG 5   5   5   ARG ARG B . n 
B 1 6   ASP 6   6   6   ASP ASP B . n 
B 1 7   LEU 7   7   7   LEU LEU B . n 
B 1 8   ILE 8   8   8   ILE ILE B . n 
B 1 9   GLN 9   9   9   GLN GLN B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  VAL 11  11  11  VAL VAL B . n 
B 1 12  GLY 12  12  12  GLY GLY B . n 
B 1 13  PHE 13  13  13  PHE PHE B . n 
B 1 14  ARG 14  14  14  ARG ARG B . n 
B 1 15  ASN 15  15  15  ASN ASN B . n 
B 1 16  VAL 16  16  16  VAL VAL B . n 
B 1 17  ARG 17  17  17  ARG ARG B . n 
B 1 18  GLU 18  18  18  GLU GLU B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  GLY 20  20  20  GLY GLY B . n 
B 1 21  GLU 21  21  21  GLU GLU B . n 
B 1 22  ILE 22  22  22  ILE ILE B . n 
B 1 23  THR 23  23  23  THR THR B . n 
B 1 24  GLY 24  24  24  GLY GLY B . n 
B 1 25  PHE 25  25  25  PHE PHE B . n 
B 1 26  GLN 26  26  26  GLN GLN B . n 
B 1 27  PHE 27  27  27  PHE PHE B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  VAL 29  29  29  VAL VAL B . n 
B 1 30  ARG 30  30  30  ARG ARG B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  PRO 32  32  32  PRO PRO B . n 
B 1 33  SER 33  33  33  SER SER B . n 
B 1 34  TYR 34  34  34  TYR TYR B . n 
B 1 35  ARG 35  35  35  ARG ARG B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  MET 37  37  37  MET MET B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  ALA 39  39  39  ALA ALA B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  ILE 42  42  42  ILE ILE B . n 
B 1 43  ASP 43  43  43  ASP ASP B . n 
B 1 44  GLY 44  44  44  GLY GLY B . n 
B 1 45  ILE 45  45  45  ILE ILE B . n 
B 1 46  GLY 46  46  46  GLY GLY B . n 
B 1 47  VAL 47  47  47  VAL VAL B . n 
B 1 48  ARG 48  48  48  ARG ARG B . n 
B 1 49  ILE 49  49  49  ILE ILE B . n 
B 1 50  PRO 50  50  50  PRO PRO B . n 
B 1 51  GLY 51  51  51  GLY GLY B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  VAL 53  53  53  VAL VAL B . n 
B 1 54  ASP 54  54  54  ASP ASP B . n 
B 1 55  VAL 55  55  55  VAL VAL B . n 
B 1 56  GLY 56  56  56  GLY GLY B . n 
B 1 57  PRO 57  57  57  PRO PRO B . n 
B 1 58  ASP 58  58  58  ASP ASP B . n 
B 1 59  VAL 59  59  59  VAL VAL B . n 
B 1 60  PRO 60  60  60  PRO PRO B . n 
B 1 61  LEU 61  61  61  LEU LEU B . n 
B 1 62  TRP 62  62  62  TRP TRP B . n 
B 1 63  THR 63  63  63  THR THR B . n 
B 1 64  LEU 64  64  64  LEU LEU B . n 
B 1 65  GLN 65  65  65  GLN GLN B . n 
B 1 66  GLY 66  66  66  GLY GLY B . n 
B 1 67  GLN 67  67  67  GLN GLN B . n 
B 1 68  GLN 68  68  68  GLN GLN B . n 
B 1 69  TYR 69  69  69  TYR TYR B . n 
B 1 70  THR 70  70  70  THR THR B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  GLU 73  73  73  GLU GLU B . n 
B 1 74  LEU 74  74  74  LEU LEU B . n 
B 1 75  TRP 75  75  75  TRP TRP B . n 
B 1 76  ASP 76  76  76  ASP ASP B . n 
B 1 77  GLY 77  77  77  GLY GLY B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  VAL 80  80  80  VAL VAL B . n 
B 1 81  ARG 81  81  81  ARG ARG B . n 
B 1 82  TRP 82  82  82  TRP TRP B . n 
B 1 83  PRO 83  83  83  PRO PRO B . n 
B 1 84  LEU 84  84  84  LEU LEU B . n 
B 1 85  GLU 85  85  85  GLU GLU B . n 
B 1 86  ASP 86  86  86  ASP ASP B . n 
B 1 87  ALA 87  87  87  ALA ALA B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  ILE 89  89  89  ILE ILE B . n 
B 1 90  ILE 90  90  90  ILE ILE B . n 
B 1 91  PHE 91  91  91  PHE PHE B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  PRO 93  93  93  PRO PRO B . n 
B 1 94  LEU 94  94  94  LEU LEU B . n 
B 1 95  PRO 95  95  95  PRO PRO B . n 
B 1 96  GLY 96  96  96  GLY GLY B . n 
B 1 97  GLY 97  97  97  GLY GLY B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 ASP 100 100 100 ASP ASP B . n 
B 1 101 GLY 101 101 101 GLY GLY B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 HIS 103 103 103 HIS HIS B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 LEU 105 105 105 LEU LEU B . n 
B 1 106 SER 106 106 106 SER SER B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 GLU 108 108 108 GLU GLU B . n 
B 1 109 LEU 109 109 109 LEU LEU B . n 
B 1 110 ARG 110 110 110 ARG ARG B . n 
B 1 111 LEU 111 111 111 LEU LEU B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 MET 113 113 113 MET MET B . n 
B 1 114 SER 114 114 114 SER SER B . n 
B 1 115 TYR 115 115 115 TYR TYR B . n 
B 1 116 ILE 116 116 116 ILE ILE B . n 
B 1 117 PRO 117 117 117 PRO PRO B . n 
B 1 118 GLN 118 118 118 GLN GLN B . n 
B 1 119 GLU 119 119 119 GLU GLU B . n 
B 1 120 HIS 120 120 120 HIS HIS B . n 
B 1 121 GLN 121 121 121 GLN GLN B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 THR 124 124 124 THR THR B . n 
B 1 125 TYR 125 125 125 TYR TYR B . n 
B 1 126 ARG 126 126 126 ARG ARG B . n 
B 1 127 VAL 127 127 127 VAL VAL B . n 
B 1 128 THR 128 128 128 THR THR B . n 
B 1 129 LYS 129 129 129 LYS LYS B . n 
B 1 130 HIS 130 130 130 HIS HIS B . n 
B 1 131 VAL 131 131 131 VAL VAL B . n 
B 1 132 THR 132 132 132 THR THR B . n 
B 1 133 LEU 133 133 133 LEU LEU B . n 
B 1 134 ALA 134 134 134 ALA ALA B . n 
B 1 135 PRO 135 135 135 PRO PRO B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 ALA 137 137 137 ALA ALA B . n 
B 1 138 SER 138 138 138 SER SER B . n 
B 1 139 GLY 139 139 139 GLY GLY B . n 
B 1 140 ALA 140 140 140 ALA ALA B . n 
B 1 141 PRO 141 141 141 PRO PRO B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 ARG 143 143 143 ARG ARG B . n 
B 1 144 TYR 144 144 144 TYR TYR B . n 
B 1 145 GLY 145 145 145 GLY GLY B . n 
B 1 146 VAL 146 146 146 VAL VAL B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 TYR 149 149 149 TYR TYR B . n 
B 1 150 SER 150 150 150 SER SER B . n 
B 1 151 TYR 151 151 151 TYR TYR B . n 
B 1 152 MET 152 152 152 MET MET B . n 
B 1 153 SER 153 153 153 SER SER B . n 
B 1 154 ASP 154 154 154 ASP ASP B . n 
B 1 155 TYR 155 155 155 TYR TYR B . n 
B 1 156 GLY 156 156 156 GLY GLY B . n 
B 1 157 THR 157 157 157 THR THR B . n 
B 1 158 VAL 158 158 158 VAL VAL B . n 
B 1 159 MET 159 159 159 MET MET B . n 
B 1 160 ASP 160 160 160 ASP ASP B . n 
B 1 161 LEU 161 161 161 LEU LEU B . n 
B 1 162 GLU 162 162 162 GLU GLU B . n 
B 1 163 THR 163 163 163 THR THR B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 MET 165 165 165 MET MET B . n 
B 1 166 ALA 166 166 166 ALA ALA B . n 
B 1 167 SER 167 167 167 SER SER B . n 
B 1 168 ILE 168 168 168 ILE ILE B . n 
B 1 169 ALA 169 169 169 ALA ALA B . n 
B 1 170 ASP 170 170 170 ASP ASP B . n 
B 1 171 LEU 171 171 171 LEU LEU B . n 
B 1 172 GLY 172 172 172 GLY GLY B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 THR 174 174 174 THR THR B . n 
B 1 175 GLY 175 175 175 GLY GLY B . n 
B 1 176 ILE 176 176 176 ILE ILE B . n 
B 1 177 GLU 177 177 177 GLU GLU B . n 
B 1 178 ILE 178 178 178 ILE ILE B . n 
B 1 179 LEU 179 179 179 LEU LEU B . n 
B 1 180 GLY 180 180 180 GLY GLY B . n 
B 1 181 GLU 181 181 181 GLU GLU B . n 
B 1 182 ALA 182 182 182 ALA ALA B . n 
B 1 183 HIS 183 183 183 HIS HIS B . n 
B 1 184 VAL 184 184 184 VAL VAL B . n 
B 1 185 PRO 185 185 185 PRO PRO B . n 
B 1 186 ASN 186 186 186 ASN ASN B . n 
B 1 187 TYR 187 187 187 TYR TYR B . n 
B 1 188 PRO 188 188 188 PRO PRO B . n 
B 1 189 ASN 189 189 189 ASN ASN B . n 
B 1 190 PRO 190 190 190 PRO PRO B . n 
B 1 191 SER 191 191 191 SER SER B . n 
B 1 192 ASP 192 192 192 ASP ASP B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 TRP 194 194 194 TRP TRP B . n 
B 1 195 VAL 195 195 195 VAL VAL B . n 
B 1 196 GLU 196 196 196 GLU GLU B . n 
B 1 197 GLN 197 197 197 GLN GLN B . n 
B 1 198 TRP 198 198 198 TRP TRP B . n 
B 1 199 PHE 199 199 199 PHE PHE B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 LEU 201 201 201 LEU LEU B . n 
B 1 202 LEU 202 202 202 LEU LEU B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 THR 204 204 204 THR THR B . n 
B 1 205 TYR 205 205 205 TYR TYR B . n 
B 1 206 GLY 206 206 206 GLY GLY B . n 
B 1 207 LEU 207 207 207 LEU LEU B . n 
B 1 208 GLU 208 208 208 GLU GLU B . n 
B 1 209 PRO 209 209 209 PRO PRO B . n 
B 1 210 THR 210 210 210 THR THR B . n 
B 1 211 ASN 211 211 211 ASN ASN B . n 
B 1 212 MET 212 212 212 MET MET B . n 
B 1 213 GLY 213 213 213 GLY GLY B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 TRP 215 215 215 TRP TRP B . n 
B 1 216 ILE 216 216 216 ILE ILE B . n 
B 1 217 ASP 217 217 217 ASP ASP B . n 
B 1 218 THR 218 218 218 THR THR B . n 
B 1 219 ARG 219 219 219 ARG ARG B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 HIS 221 221 221 HIS HIS B . n 
B 1 222 SER 222 222 222 SER SER B . n 
B 1 223 SER 223 223 223 SER SER B . n 
B 1 224 GLY 224 224 224 GLY GLY B . n 
B 1 225 PRO 225 225 225 PRO PRO B . n 
B 1 226 ASN 226 226 226 ASN ASN B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 ARG 228 228 228 ARG ARG B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 MET 230 230 230 MET MET B . n 
B 1 231 THR 231 231 231 THR THR B . n 
B 1 232 VAL 232 232 232 VAL VAL B . n 
B 1 233 GLU 233 233 233 GLU GLU B . n 
B 1 234 GLU 234 234 234 GLU GLU B . n 
B 1 235 GLY 235 235 235 GLY GLY B . n 
B 1 236 ALA 236 236 236 ALA ALA B . n 
B 1 237 ALA 237 237 237 ALA ALA B . n 
B 1 238 ALA 238 238 238 ALA ALA B . n 
B 1 239 LEU 239 239 239 LEU LEU B . n 
B 1 240 GLN 240 240 240 GLN GLN B . n 
B 1 241 ARG 241 241 241 ARG ARG B . n 
B 1 242 ASP 242 242 242 ASP ASP B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 ARG 244 244 244 ARG ARG B . n 
B 1 245 LEU 245 245 245 LEU LEU B . n 
B 1 246 ALA 246 246 246 ALA ALA B . n 
B 1 247 LYS 247 247 247 LYS LYS B . n 
B 1 248 ARG 248 248 248 ARG ARG B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 GLY 250 250 250 GLY GLY B . n 
B 1 251 PHE 251 251 251 PHE PHE B . n 
B 1 252 ARG 252 252 252 ARG ARG B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 VAL 254 254 254 VAL VAL B . n 
B 1 255 ARG 255 255 255 ARG ARG B . n 
B 1 256 PRO 256 256 256 PRO PRO B . n 
B 1 257 LYS 257 257 257 LYS LYS B . n 
B 1 258 ILE 258 258 258 ILE ILE B . n 
B 1 259 GLY 259 259 259 GLY GLY B . n 
B 1 260 VAL 260 260 260 VAL VAL B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 SER 262 262 262 SER SER B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 ASP 264 264 264 ASP ASP B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 ILE 266 266 266 ILE ILE B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 HIS 268 268 268 HIS HIS B . n 
B 1 269 PRO 269 269 269 PRO PRO B . n 
B 1 270 ILE 270 270 270 ILE ILE B . n 
B 1 271 TRP 271 271 271 TRP TRP B . n 
B 1 272 THR 272 272 272 THR THR B . n 
B 1 273 GLU 273 273 273 GLU GLU B . n 
B 1 274 VAL 274 274 274 VAL VAL B . n 
B 1 275 VAL 275 275 275 VAL VAL B . n 
B 1 276 GLU 276 276 276 GLU GLU B . n 
B 1 277 ALA 277 277 277 ALA ALA B . n 
B 1 278 SER 278 278 278 SER SER B . n 
B 1 279 LEU 279 279 279 LEU LEU B . n 
B 1 280 PRO 280 280 280 PRO PRO B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 ALA 282 282 282 ALA ALA B . n 
B 1 283 GLU 283 283 283 GLU GLU B . n 
B 1 284 GLU 284 284 284 GLU GLU B . n 
B 1 285 LEU 285 285 285 LEU LEU B . n 
B 1 286 ASP 286 286 286 ASP ASP B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 ILE 288 288 288 ILE ILE B . n 
B 1 289 ILE 289 289 289 ILE ILE B . n 
B 1 290 CYS 290 290 290 CYS CYS B . n 
B 1 291 PRO 291 291 291 PRO PRO B . n 
B 1 292 GLU 292 292 292 GLU GLU B . n 
B 1 293 ILE 293 293 293 ILE ILE B . n 
B 1 294 HIS 294 294 294 HIS HIS B . n 
B 1 295 SER 295 295 295 SER SER B . n 
B 1 296 PRO 296 296 296 PRO PRO B . n 
B 1 297 THR 297 297 297 THR THR B . n 
B 1 298 PRO 298 298 298 PRO PRO B . n 
B 1 299 ILE 299 299 299 ILE ILE B . n 
B 1 300 LYS 300 300 300 LYS LYS B . n 
B 1 301 HIS 301 301 301 HIS HIS B . n 
B 1 302 GLU 302 302 302 GLU GLU B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 ASP 305 305 305 ASP ASP B . n 
B 1 306 ASP 306 306 306 ASP ASP B . n 
B 1 307 TYR 307 307 307 TYR TYR B . n 
B 1 308 ILE 308 308 308 ILE ILE B . n 
B 1 309 ALA 309 309 309 ALA ALA B . n 
B 1 310 LEU 310 310 310 LEU LEU B . n 
B 1 311 ILE 311 311 311 ILE ILE B . n 
B 1 312 ARG 312 312 312 ARG ARG B . n 
B 1 313 ARG 313 313 313 ARG ARG B . n 
B 1 314 THR 314 314 314 THR THR B . n 
B 1 315 GLY 315 315 315 GLY GLY B . n 
B 1 316 THR 316 316 316 THR THR B . n 
B 1 317 LYS 317 317 317 LYS LYS B . n 
B 1 318 HIS 318 318 318 HIS HIS B . n 
B 1 319 PHE 319 319 319 PHE PHE B . n 
B 1 320 GLY 320 320 320 GLY GLY B . n 
B 1 321 LEU 321 321 321 LEU LEU B . n 
B 1 322 LEU 322 322 322 LEU LEU B . n 
B 1 323 LEU 323 323 323 LEU LEU B . n 
B 1 324 ASP 324 324 324 ASP ASP B . n 
B 1 325 THR 325 325 325 THR THR B . n 
B 1 326 GLY 326 326 326 GLY GLY B . n 
B 1 327 ILE 327 327 327 ILE ILE B . n 
B 1 328 PHE 328 328 328 PHE PHE B . n 
B 1 329 GLN 329 329 329 GLN GLN B . n 
B 1 330 ASP 330 330 330 ASP ASP B . n 
B 1 331 ARG 331 331 331 ARG ARG B . n 
B 1 332 PRO 332 332 332 PRO PRO B . n 
B 1 333 ILE 333 333 333 ILE ILE B . n 
B 1 334 PRO 334 334 334 PRO PRO B . n 
B 1 335 LEU 335 335 335 LEU LEU B . n 
B 1 336 LYS 336 336 336 LYS LYS B . n 
B 1 337 PRO 337 337 337 PRO PRO B . n 
B 1 338 GLY 338 338 338 GLY GLY B . n 
B 1 339 GLU 339 339 339 GLU GLU B . n 
B 1 340 LEU 340 340 340 LEU LEU B . n 
B 1 341 PRO 341 341 341 PRO PRO B . n 
B 1 342 GLY 342 342 342 GLY GLY B . n 
B 1 343 GLN 343 343 343 GLN GLN B . n 
B 1 344 ARG 344 344 344 ARG ARG B . n 
B 1 345 PRO 345 345 345 PRO PRO B . n 
B 1 346 ALA 346 346 346 ALA ALA B . n 
B 1 347 PHE 347 347 347 PHE PHE B . n 
B 1 348 LEU 348 348 348 LEU LEU B . n 
B 1 349 ASP 349 349 349 ASP ASP B . n 
B 1 350 GLY 350 350 350 GLY GLY B . n 
B 1 351 ILE 351 351 351 ILE ILE B . n 
B 1 352 HIS 352 352 352 HIS HIS B . n 
B 1 353 VAL 353 353 353 VAL VAL B . n 
B 1 354 ASP 354 354 354 ASP ASP B . n 
B 1 355 PRO 355 355 355 PRO PRO B . n 
B 1 356 ASN 356 356 356 ASN ASN B . n 
B 1 357 ASP 357 357 357 ASP ASP B . n 
B 1 358 VAL 358 358 358 VAL VAL B . n 
B 1 359 PHE 359 359 359 PHE PHE B . n 
B 1 360 ASP 360 360 360 ASP ASP B . n 
B 1 361 VAL 361 361 361 VAL VAL B . n 
B 1 362 ILE 362 362 362 ILE ILE B . n 
B 1 363 GLU 363 363 363 GLU GLU B . n 
B 1 364 ASN 364 364 364 ASN ASN B . n 
B 1 365 VAL 365 365 365 VAL VAL B . n 
B 1 366 VAL 366 366 366 VAL VAL B . n 
B 1 367 PHE 367 367 367 PHE PHE B . n 
B 1 368 ILE 368 368 368 ILE ILE B . n 
B 1 369 GLN 369 369 369 GLN GLN B . n 
B 1 370 ALA 370 370 370 ALA ALA B . n 
B 1 371 LYS 371 371 371 LYS LYS B . n 
B 1 372 PHE 372 372 372 PHE PHE B . n 
B 1 373 HIS 373 373 373 HIS HIS B . n 
B 1 374 ASP 374 374 374 ASP ASP B . n 
B 1 375 ILE 375 375 375 ILE ILE B . n 
B 1 376 ASP 376 376 376 ASP ASP B . n 
B 1 377 GLU 377 377 377 GLU GLU B . n 
B 1 378 GLU 378 378 378 GLU GLU B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 ASP 380 380 380 ASP ASP B . n 
B 1 381 ASP 381 381 381 ASP ASP B . n 
B 1 382 LYS 382 382 382 LYS LYS B . n 
B 1 383 GLN 383 383 383 GLN GLN B . n 
B 1 384 ILE 384 384 384 ILE ILE B . n 
B 1 385 PRO 385 385 385 PRO PRO B . n 
B 1 386 TRP 386 386 386 TRP TRP B . n 
B 1 387 GLU 387 387 387 GLU GLU B . n 
B 1 388 PRO 388 388 388 PRO PRO B . n 
B 1 389 VAL 389 389 389 VAL VAL B . n 
B 1 390 LEU 390 390 390 LEU LEU B . n 
B 1 391 LYS 391 391 391 LYS LYS B . n 
B 1 392 ALA 392 392 392 ALA ALA B . n 
B 1 393 LEU 393 393 393 LEU LEU B . n 
B 1 394 LYS 394 394 394 LYS LYS B . n 
B 1 395 ASP 395 395 395 ASP ASP B . n 
B 1 396 ALA 396 396 396 ALA ALA B . n 
B 1 397 GLY 397 397 397 GLY GLY B . n 
B 1 398 TYR 398 398 398 TYR TYR B . n 
B 1 399 THR 399 399 399 THR THR B . n 
B 1 400 GLY 400 400 400 GLY GLY B . n 
B 1 401 TYR 401 401 401 TYR TYR B . n 
B 1 402 LEU 402 402 402 LEU LEU B . n 
B 1 403 SER 403 403 403 SER SER B . n 
B 1 404 SER 404 404 404 SER SER B . n 
B 1 405 GLU 405 405 405 GLU GLU B . n 
B 1 406 TYR 406 406 406 TYR TYR B . n 
B 1 407 GLU 407 407 407 GLU GLU B . n 
B 1 408 GLY 408 408 408 GLY GLY B . n 
B 1 409 GLU 409 409 409 GLU GLU B . n 
B 1 410 ARG 410 410 410 ARG ARG B . n 
B 1 411 GLU 411 411 411 GLU GLU B . n 
B 1 412 PRO 412 412 412 PRO PRO B . n 
B 1 413 TRP 413 413 413 TRP TRP B . n 
B 1 414 ARG 414 414 414 ARG ARG B . n 
B 1 415 SER 415 415 415 SER SER B . n 
B 1 416 ILE 416 416 416 ILE ILE B . n 
B 1 417 GLU 417 417 417 GLU GLU B . n 
B 1 418 GLN 418 418 418 GLN GLN B . n 
B 1 419 VAL 419 419 419 VAL VAL B . n 
B 1 420 ARG 420 420 420 ARG ARG B . n 
B 1 421 ARG 421 421 421 ARG ARG B . n 
B 1 422 GLN 422 422 422 GLN GLN B . n 
B 1 423 HIS 423 423 423 HIS HIS B . n 
B 1 424 SER 424 424 424 SER SER B . n 
B 1 425 LEU 425 425 425 LEU LEU B . n 
B 1 426 ILE 426 426 426 ILE ILE B . n 
B 1 427 ARG 427 427 427 ARG ARG B . n 
B 1 428 GLN 428 428 428 GLN GLN B . n 
B 1 429 ILE 429 429 429 ILE ILE B . n 
B 1 430 ALA 430 430 430 ALA ALA B . n 
B 1 431 ASP 431 431 431 ASP ASP B . n 
B 1 432 ARG 432 432 432 ARG ARG B . n 
B 1 433 LEU 433 433 433 LEU LEU B . n 
B 1 434 ALA 434 434 ?   ?   ?   B . n 
B 1 435 GLU 435 435 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 MN 1 501 1 MN MN A . 
D 2 MN 1 501 2 MN MN B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UN2 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UN2 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UN2 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8UN2 
_struct.title                        'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type (cryo-EM)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UN2 
_struct_keywords.text            
;bacterial C-glucosyl deglycosidase, C-C bond cleavage, C-glucosyl flavonoids, Microbacterium tetsaceum NS220, plant endosymbiont, N-terminal DUF6379 beta-sandwich domain, C-terminal TIM-barrel domain, homodimer, LYASE
;
_struct_keywords.pdbx_keywords   LYASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A147EV52_MICTE 
_struct_ref.pdbx_db_accession          A0A147EV52 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MLLERDLIQSVGFRNVREGGEITGFQFRVRMPSYRGMAASLIDGIGVRIPGLVDVGPDVPLWTLQGQQYTLAELWDGDGV
RWPLEDAAIIFVPLPGGLPDGVHELSIELRLRMSYIPQEHQPSTYRVTKHVTLAPEASGAPFRYGVSLYSYMSDYGTVMD
LETAMASIADLGATGIEILGEAHVPNYPNPSDEWVEQWFALLSTYGLEPTNMGSWIDTRLHSSGPNGRDMTVEEGAAALQ
RDLRLAKRLGFRFVRPKIGVVSSDLIPHPIWTEVVEASLPLAEELDVIICPEIHSPTPIKHEVVDDYIALIRRTGTKHFG
LLLDTGIFQDRPIPLKPGELPGQRPAFLDGIHVDPNDVFDVIENVVFIQAKFHDIDEELDDKQIPWEPVLKALKDAGYTG
YLSSEYEGEREPWRSIEQVRRQHSLIRQIADRL
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UN2 A 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
2 1 8UN2 B 1 ? 433 ? A0A147EV52 1 ? 433 ? 1 433 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8UN2 ALA A 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 1 
1 8UN2 GLU A 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 2 
2 8UN2 ALA B 434 ? UNP A0A147EV52 ? ? 'expression tag' 434 3 
2 8UN2 GLU B 435 ? UNP A0A147EV52 ? ? 'expression tag' 435 4 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'confirmed by gel filtration, cryo-EM and X-ray crystallography' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 70  ? GLY A 77  ? THR A 70  GLY A 77  1 ? 8  
HELX_P HELX_P2  AA2 PRO A 117 ? GLN A 121 ? PRO A 117 GLN A 121 5 ? 5  
HELX_P HELX_P3  AA3 TYR A 149 ? TYR A 151 ? TYR A 149 TYR A 151 5 ? 3  
HELX_P HELX_P4  AA4 ASP A 160 ? LEU A 171 ? ASP A 160 LEU A 171 1 ? 12 
HELX_P HELX_P5  AA5 GLY A 180 ? VAL A 184 ? GLY A 180 VAL A 184 1 ? 5  
HELX_P HELX_P6  AA6 SER A 191 ? GLY A 206 ? SER A 191 GLY A 206 1 ? 16 
HELX_P HELX_P7  AA7 THR A 231 ? GLY A 250 ? THR A 231 GLY A 250 1 ? 20 
HELX_P HELX_P8  AA8 ILE A 270 ? ASP A 286 ? ILE A 270 ASP A 286 1 ? 17 
HELX_P HELX_P9  AA9 HIS A 301 ? GLY A 315 ? HIS A 301 GLY A 315 1 ? 15 
HELX_P HELX_P10 AB1 GLY A 326 ? GLN A 329 ? GLY A 326 GLN A 329 5 ? 4  
HELX_P HELX_P11 AB2 PRO A 345 ? GLY A 350 ? PRO A 345 GLY A 350 5 ? 6  
HELX_P HELX_P12 AB3 ASP A 354 ? ASP A 360 ? ASP A 354 ASP A 360 5 ? 7  
HELX_P HELX_P13 AB4 PRO A 385 ? ALA A 396 ? PRO A 385 ALA A 396 1 ? 12 
HELX_P HELX_P14 AB5 TRP A 413 ? LEU A 433 ? TRP A 413 LEU A 433 1 ? 21 
HELX_P HELX_P15 AB6 THR B 70  ? GLY B 77  ? THR B 70  GLY B 77  1 ? 8  
HELX_P HELX_P16 AB7 PRO B 117 ? GLN B 121 ? PRO B 117 GLN B 121 5 ? 5  
HELX_P HELX_P17 AB8 TYR B 149 ? TYR B 151 ? TYR B 149 TYR B 151 5 ? 3  
HELX_P HELX_P18 AB9 ASP B 160 ? LEU B 171 ? ASP B 160 LEU B 171 1 ? 12 
HELX_P HELX_P19 AC1 GLY B 180 ? VAL B 184 ? GLY B 180 VAL B 184 1 ? 5  
HELX_P HELX_P20 AC2 SER B 191 ? GLY B 206 ? SER B 191 GLY B 206 1 ? 16 
HELX_P HELX_P21 AC3 THR B 231 ? GLY B 250 ? THR B 231 GLY B 250 1 ? 20 
HELX_P HELX_P22 AC4 ILE B 270 ? ASP B 286 ? ILE B 270 ASP B 286 1 ? 17 
HELX_P HELX_P23 AC5 HIS B 301 ? GLY B 315 ? HIS B 301 GLY B 315 1 ? 15 
HELX_P HELX_P24 AC6 GLY B 326 ? GLN B 329 ? GLY B 326 GLN B 329 5 ? 4  
HELX_P HELX_P25 AC7 PRO B 345 ? GLY B 350 ? PRO B 345 GLY B 350 5 ? 6  
HELX_P HELX_P26 AC8 ASP B 354 ? ASP B 360 ? ASP B 354 ASP B 360 5 ? 7  
HELX_P HELX_P27 AC9 PRO B 385 ? ALA B 396 ? PRO B 385 ALA B 396 1 ? 12 
HELX_P HELX_P28 AD1 TRP B 413 ? LEU B 433 ? TRP B 413 LEU B 433 1 ? 21 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1 metalc ? ? A GLU 292 OE2 ? ? ? 1_555 C MN . MN ? ? A GLU 292 A MN 501 1_555 ? ? ? ? ? ? ? 2.009 ? ? 
metalc2 metalc ? ? A ASP 324 OD1 ? ? ? 1_555 C MN . MN ? ? A ASP 324 A MN 501 1_555 ? ? ? ? ? ? ? 2.209 ? ? 
metalc3 metalc ? ? A GLN 369 OE1 ? ? ? 1_555 C MN . MN ? ? A GLN 369 A MN 501 1_555 ? ? ? ? ? ? ? 2.155 ? ? 
metalc4 metalc ? ? A GLU 405 OE1 ? ? ? 1_555 C MN . MN ? ? A GLU 405 A MN 501 1_555 ? ? ? ? ? ? ? 2.648 ? ? 
metalc5 metalc ? ? B GLU 292 OE2 ? ? ? 1_555 D MN . MN ? ? B GLU 292 B MN 501 1_555 ? ? ? ? ? ? ? 2.014 ? ? 
metalc6 metalc ? ? B ASP 324 OD1 ? ? ? 1_555 D MN . MN ? ? B ASP 324 B MN 501 1_555 ? ? ? ? ? ? ? 2.196 ? ? 
metalc7 metalc ? ? B GLN 369 OE1 ? ? ? 1_555 D MN . MN ? ? B GLN 369 B MN 501 1_555 ? ? ? ? ? ? ? 2.164 ? ? 
metalc8 metalc ? ? B GLU 405 OE1 ? ? ? 1_555 D MN . MN ? ? B GLU 405 B MN 501 1_555 ? ? ? ? ? ? ? 2.646 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE2 ? A GLU 292 ? A GLU 292 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OD1 ? A ASP 324 ? A ASP 324 ? 1_555 88.4  ? 
2  OE2 ? A GLU 292 ? A GLU 292 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OE1 ? A GLN 369 ? A GLN 369 ? 1_555 87.4  ? 
3  OD1 ? A ASP 324 ? A ASP 324 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OE1 ? A GLN 369 ? A GLN 369 ? 1_555 85.8  ? 
4  OE2 ? A GLU 292 ? A GLU 292 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OE1 ? A GLU 405 ? A GLU 405 ? 1_555 166.1 ? 
5  OD1 ? A ASP 324 ? A ASP 324 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OE1 ? A GLU 405 ? A GLU 405 ? 1_555 97.1  ? 
6  OE1 ? A GLN 369 ? A GLN 369 ? 1_555 MN ? C MN . ? A MN 501 ? 1_555 OE1 ? A GLU 405 ? A GLU 405 ? 1_555 80.3  ? 
7  OE2 ? B GLU 292 ? B GLU 292 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OD1 ? B ASP 324 ? B ASP 324 ? 1_555 88.6  ? 
8  OE2 ? B GLU 292 ? B GLU 292 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OE1 ? B GLN 369 ? B GLN 369 ? 1_555 87.0  ? 
9  OD1 ? B ASP 324 ? B ASP 324 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OE1 ? B GLN 369 ? B GLN 369 ? 1_555 85.9  ? 
10 OE2 ? B GLU 292 ? B GLU 292 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OE1 ? B GLU 405 ? B GLU 405 ? 1_555 165.4 ? 
11 OD1 ? B ASP 324 ? B ASP 324 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OE1 ? B GLU 405 ? B GLU 405 ? 1_555 97.4  ? 
12 OE1 ? B GLN 369 ? B GLN 369 ? 1_555 MN ? D MN . ? B MN 501 ? 1_555 OE1 ? B GLU 405 ? B GLU 405 ? 1_555 80.2  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 121 A . ? GLN 121 A PRO 122 A ? PRO 122 A 1 0.32 
2 ALA 140 A . ? ALA 140 A PRO 141 A ? PRO 141 A 1 8.05 
3 TYR 187 A . ? TYR 187 A PRO 188 A ? PRO 188 A 1 0.58 
4 SER 295 A . ? SER 295 A PRO 296 A ? PRO 296 A 1 8.96 
5 GLN 121 B . ? GLN 121 B PRO 122 B ? PRO 122 B 1 0.41 
6 ALA 140 B . ? ALA 140 B PRO 141 B ? PRO 141 B 1 8.05 
7 TYR 187 B . ? TYR 187 B PRO 188 B ? PRO 188 B 1 0.64 
8 SER 295 B . ? SER 295 B PRO 296 B ? PRO 296 B 1 8.89 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5 ? 
AA2 ? 2 ? 
AA3 ? 4 ? 
AA4 ? 9 ? 
AA5 ? 5 ? 
AA6 ? 2 ? 
AA7 ? 4 ? 
AA8 ? 9 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
AA4 6 7 ? parallel      
AA4 7 8 ? parallel      
AA4 8 9 ? parallel      
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA8 3 4 ? parallel      
AA8 4 5 ? parallel      
AA8 5 6 ? parallel      
AA8 6 7 ? parallel      
AA8 7 8 ? parallel      
AA8 8 9 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG A 14  ? GLU A 18  ? ARG A 14  GLU A 18  
AA1 2 GLU A 21  ? VAL A 29  ? GLU A 21  VAL A 29  
AA1 3 ALA A 88  ? PRO A 93  ? ALA A 88  PRO A 93  
AA1 4 LEU A 61  ? LEU A 64  ? LEU A 61  LEU A 64  
AA1 5 GLN A 67  ? TYR A 69  ? GLN A 67  TYR A 69  
AA2 1 MET A 37  ? ALA A 38  ? MET A 37  ALA A 38  
AA2 2 ARG A 81  ? TRP A 82  ? ARG A 81  TRP A 82  
AA3 1 VAL A 53  ? ASP A 54  ? VAL A 53  ASP A 54  
AA3 2 ILE A 42  ? ILE A 49  ? ILE A 42  ILE A 49  
AA3 3 VAL A 102 ? LEU A 111 ? VAL A 102 LEU A 111 
AA3 4 SER A 123 ? THR A 132 ? SER A 123 THR A 132 
AA4 1 ILE A 288 ? ILE A 289 ? ILE A 288 ILE A 289 
AA4 2 PHE A 253 ? ILE A 258 ? PHE A 253 ILE A 258 
AA4 3 GLU A 208 ? ILE A 216 ? GLU A 208 ILE A 216 
AA4 4 GLY A 175 ? LEU A 179 ? GLY A 175 LEU A 179 
AA4 5 ARG A 143 ? SER A 147 ? ARG A 143 SER A 147 
AA4 6 TYR A 401 ? TYR A 406 ? TYR A 401 TYR A 406 
AA4 7 VAL A 365 ? PHE A 372 ? VAL A 365 PHE A 372 
AA4 8 LEU A 321 ? ASP A 324 ? LEU A 321 ASP A 324 
AA4 9 GLU A 292 ? ILE A 293 ? GLU A 292 ILE A 293 
AA5 1 ARG B 14  ? GLU B 18  ? ARG B 14  GLU B 18  
AA5 2 GLU B 21  ? VAL B 29  ? GLU B 21  VAL B 29  
AA5 3 ALA B 88  ? PRO B 93  ? ALA B 88  PRO B 93  
AA5 4 LEU B 61  ? LEU B 64  ? LEU B 61  LEU B 64  
AA5 5 GLN B 67  ? TYR B 69  ? GLN B 67  TYR B 69  
AA6 1 MET B 37  ? ALA B 38  ? MET B 37  ALA B 38  
AA6 2 ARG B 81  ? TRP B 82  ? ARG B 81  TRP B 82  
AA7 1 VAL B 53  ? ASP B 54  ? VAL B 53  ASP B 54  
AA7 2 ILE B 42  ? ILE B 49  ? ILE B 42  ILE B 49  
AA7 3 VAL B 102 ? LEU B 111 ? VAL B 102 LEU B 111 
AA7 4 SER B 123 ? THR B 132 ? SER B 123 THR B 132 
AA8 1 ILE B 288 ? ILE B 289 ? ILE B 288 ILE B 289 
AA8 2 PHE B 253 ? ILE B 258 ? PHE B 253 ILE B 258 
AA8 3 GLU B 208 ? ILE B 216 ? GLU B 208 ILE B 216 
AA8 4 GLY B 175 ? LEU B 179 ? GLY B 175 LEU B 179 
AA8 5 ARG B 143 ? SER B 147 ? ARG B 143 SER B 147 
AA8 6 TYR B 401 ? TYR B 406 ? TYR B 401 TYR B 406 
AA8 7 VAL B 365 ? PHE B 372 ? VAL B 365 PHE B 372 
AA8 8 LEU B 321 ? ASP B 324 ? LEU B 321 ASP B 324 
AA8 9 GLU B 292 ? ILE B 293 ? GLU B 292 ILE B 293 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 16  ? N VAL A 16  O GLY A 24  ? O GLY A 24  
AA1 2 3 N PHE A 27  ? N PHE A 27  O ILE A 90  ? O ILE A 90  
AA1 3 4 O PHE A 91  ? O PHE A 91  N LEU A 61  ? N LEU A 61  
AA1 4 5 N TRP A 62  ? N TRP A 62  O TYR A 69  ? O TYR A 69  
AA2 1 2 N MET A 37  ? N MET A 37  O TRP A 82  ? O TRP A 82  
AA3 1 2 O VAL A 53  ? O VAL A 53  N ILE A 49  ? N ILE A 49  
AA3 2 3 N GLY A 44  ? N GLY A 44  O ARG A 110 ? O ARG A 110 
AA3 3 4 N HIS A 103 ? N HIS A 103 O VAL A 131 ? O VAL A 131 
AA4 1 2 O ILE A 288 ? O ILE A 288 N VAL A 254 ? N VAL A 254 
AA4 2 3 O ARG A 255 ? O ARG A 255 N SER A 214 ? N SER A 214 
AA4 3 4 O THR A 210 ? O THR A 210 N ILE A 176 ? N ILE A 176 
AA4 4 5 O GLU A 177 ? O GLU A 177 N VAL A 146 ? N VAL A 146 
AA4 5 6 N SER A 147 ? N SER A 147 O SER A 404 ? O SER A 404 
AA4 6 7 O SER A 403 ? O SER A 403 N ALA A 370 ? N ALA A 370 
AA4 7 8 O VAL A 366 ? O VAL A 366 N LEU A 321 ? N LEU A 321 
AA4 8 9 O ASP A 324 ? O ASP A 324 N ILE A 293 ? N ILE A 293 
AA5 1 2 N VAL B 16  ? N VAL B 16  O GLY B 24  ? O GLY B 24  
AA5 2 3 N PHE B 27  ? N PHE B 27  O ILE B 90  ? O ILE B 90  
AA5 3 4 O PHE B 91  ? O PHE B 91  N LEU B 61  ? N LEU B 61  
AA5 4 5 N TRP B 62  ? N TRP B 62  O TYR B 69  ? O TYR B 69  
AA6 1 2 N MET B 37  ? N MET B 37  O TRP B 82  ? O TRP B 82  
AA7 1 2 O VAL B 53  ? O VAL B 53  N ILE B 49  ? N ILE B 49  
AA7 2 3 N GLY B 44  ? N GLY B 44  O ARG B 110 ? O ARG B 110 
AA7 3 4 N HIS B 103 ? N HIS B 103 O VAL B 131 ? O VAL B 131 
AA8 1 2 O ILE B 288 ? O ILE B 288 N VAL B 254 ? N VAL B 254 
AA8 2 3 O ARG B 255 ? O ARG B 255 N SER B 214 ? N SER B 214 
AA8 3 4 O THR B 210 ? O THR B 210 N ILE B 176 ? N ILE B 176 
AA8 4 5 O GLU B 177 ? O GLU B 177 N VAL B 146 ? N VAL B 146 
AA8 5 6 N SER B 147 ? N SER B 147 O SER B 404 ? O SER B 404 
AA8 6 7 O SER B 403 ? O SER B 403 N ALA B 370 ? N ALA B 370 
AA8 7 8 O VAL B 366 ? O VAL B 366 N LEU B 321 ? N LEU B 321 
AA8 8 9 O ASP B 324 ? O ASP B 324 N ILE B 293 ? N ILE B 293 
# 
_pdbx_entry_details.entry_id                   8UN2 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 160 ? ? -117.75 -169.10 
2 1 ARG A 219 ? ? -98.84  37.41   
3 1 ASN A 226 ? ? -96.56  30.84   
4 1 GLN A 383 ? ? -130.43 -31.21  
5 1 ASP B 160 ? ? -117.80 -169.17 
6 1 ARG B 219 ? ? -98.78  37.39   
7 1 ASN B 226 ? ? -96.60  30.81   
8 1 GLN B 383 ? ? -130.44 -31.20  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8UN2 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  . 
_em_3d_fitting_list.pdb_chain_id                  . 
_em_3d_fitting_list.pdb_chain_residue_range       . 
_em_3d_fitting_list.details                       'X-ray model of the same sample' 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   Other 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                ? 
_em_3d_fitting_list.initial_refinement_model_id   ? 
# 
_em_3d_reconstruction.entry_id                    8UN2 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   'BACK PROJECTION' 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               734119 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '25 mM HEPES pH 7.5, 150 mM NaCl, 0.15 mM MnCl2' 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'C-glucosyl deglycosidase from Microbacterium testaceum' 
_em_entity_assembly.details              'wild type' 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        8UN2 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         
;Data collected on the Karolinska Institutet's Krios G3i equipped with a cold-FEG
;
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             200 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'ZEMLIN TABLEAU' 
_em_imaging.c2_aperture_diameter            20 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        UltrAuFoil 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              8UN2 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8UN2 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
_em_single_particle_entity.entry_id              8UN2 
_em_single_particle_entity.id                    1 
_em_single_particle_entity.image_processing_id   1 
_em_single_particle_entity.point_symmetry        C2 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A ALA 434 ? A ALA 434 
2 1 Y 1 A GLU 435 ? A GLU 435 
3 1 Y 1 B ALA 434 ? B ALA 434 
4 1 Y 1 B GLU 435 ? B GLU 435 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
MN  MN   MN N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-18 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           8UN2 
_em_admin.last_update        2025-04-23 
_em_admin.map_release_date   2025-04-23 
_em_admin.title              'Microbacterium testaceum C-glucosyl deglycosidase (CGD), wild type (cryo-EM)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          2033 
_em_entity_assembly_naturalsource.organism             'Microbacterium testaceum' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               NS220 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          37762 
_em_entity_assembly_recombinant.organism             'Escherichia coli B' 
_em_entity_assembly_recombinant.plasmid              pNIC-CTHO 
_em_entity_assembly_recombinant.strain               '(DE3)-T1' 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         56 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_imaging_optics.chr_aberration_corrector   ? 
_em_imaging_optics.energyfilter_lower         ? 
_em_imaging_optics.energyfilter_slit_width    10 
_em_imaging_optics.energyfilter_name          'GIF Bioquantum' 
_em_imaging_optics.energyfilter_upper         ? 
_em_imaging_optics.id                         1 
_em_imaging_optics.imaging_id                 1 
_em_imaging_optics.phase_plate                ? 
_em_imaging_optics.sph_aberration_corrector   ? 
_em_imaging_optics.details                    ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? Warp      0.9   
'IMAGE ACQUISITION'        ? 2  ? ? 1 EPU       3.1   
MASKING                    ? 3  ? ? ? ?         ?     
'CTF CORRECTION'           ? 4  1 ? ? Warp      0.9   
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?     
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?     
'MODEL FITTING'            ? 7  ? 1 ? Coot      ?     
OTHER                      ? 8  ? ? ? ?         ?     
'INITIAL EULER ASSIGNMENT' ? 9  1 ? ? cryoSPARC 4.3.1 
'FINAL EULER ASSIGNMENT'   ? 10 1 ? ? ?         ?     
CLASSIFICATION             ? 11 1 ? ? cryoSPARC 4.3.1 
RECONSTRUCTION             ? 12 1 ? ? cryoSPARC 4.3.1 
'MODEL REFINEMENT'         ? 13 ? 1 ? PHENIX    1.14  
# 
_em_specimen.concentration           3 
_em_specimen.details                 'monodisperse sample' 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Other government' Sweden 'Formas 2017-00983'                                   1 
'Other government' Sweden 'VR 2017-03877'                                       2 
'Other private'    Sweden 'Oscar and Lili Lamm Memorial Foundation DO2017-0020' 3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      Other 
_pdbx_initial_refinement_model.accession_code   ? 
# 
_atom_sites.entry_id                    8UN2 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MN 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . MET A 1 1   ? 105.598 113.539 114.824 1.00 85.84  ? 1   MET A N   1 
ATOM   2    C  CA  . MET A 1 1   ? 105.227 112.775 113.645 1.00 85.84  ? 1   MET A CA  1 
ATOM   3    C  C   . MET A 1 1   ? 105.599 113.523 112.378 1.00 85.84  ? 1   MET A C   1 
ATOM   4    O  O   . MET A 1 1   ? 105.460 114.738 112.302 1.00 85.84  ? 1   MET A O   1 
ATOM   5    C  CB  . MET A 1 1   ? 103.732 112.470 113.655 1.00 85.84  ? 1   MET A CB  1 
ATOM   6    C  CG  . MET A 1 1   ? 103.372 111.166 114.336 1.00 85.84  ? 1   MET A CG  1 
ATOM   7    S  SD  . MET A 1 1   ? 101.600 110.883 114.400 1.00 85.84  ? 1   MET A SD  1 
ATOM   8    C  CE  . MET A 1 1   ? 101.133 111.374 112.745 1.00 85.84  ? 1   MET A CE  1 
ATOM   9    N  N   . LEU A 1 2   ? 106.071 112.784 111.384 1.00 78.20  ? 2   LEU A N   1 
ATOM   10   C  CA  . LEU A 1 2   ? 106.476 113.377 110.125 1.00 78.20  ? 2   LEU A CA  1 
ATOM   11   C  C   . LEU A 1 2   ? 105.306 113.408 109.150 1.00 78.20  ? 2   LEU A C   1 
ATOM   12   O  O   . LEU A 1 2   ? 104.311 112.704 109.312 1.00 78.20  ? 2   LEU A O   1 
ATOM   13   C  CB  . LEU A 1 2   ? 107.644 112.597 109.535 1.00 78.20  ? 2   LEU A CB  1 
ATOM   14   C  CG  . LEU A 1 2   ? 108.933 112.675 110.348 1.00 78.20  ? 2   LEU A CG  1 
ATOM   15   C  CD1 . LEU A 1 2   ? 109.758 111.440 110.136 1.00 78.20  ? 2   LEU A CD1 1 
ATOM   16   C  CD2 . LEU A 1 2   ? 109.726 113.900 109.966 1.00 78.20  ? 2   LEU A CD2 1 
ATOM   17   N  N   . LEU A 1 3   ? 105.437 114.244 108.129 1.00 74.12  ? 3   LEU A N   1 
ATOM   18   C  CA  . LEU A 1 3   ? 104.418 114.413 107.108 1.00 74.12  ? 3   LEU A CA  1 
ATOM   19   C  C   . LEU A 1 3   ? 104.981 114.022 105.748 1.00 74.12  ? 3   LEU A C   1 
ATOM   20   O  O   . LEU A 1 3   ? 106.161 113.708 105.614 1.00 74.12  ? 3   LEU A O   1 
ATOM   21   C  CB  . LEU A 1 3   ? 103.907 115.856 107.096 1.00 74.12  ? 3   LEU A CB  1 
ATOM   22   C  CG  . LEU A 1 3   ? 103.262 116.307 108.405 1.00 74.12  ? 3   LEU A CG  1 
ATOM   23   C  CD1 . LEU A 1 3   ? 103.206 117.806 108.512 1.00 74.12  ? 3   LEU A CD1 1 
ATOM   24   C  CD2 . LEU A 1 3   ? 101.882 115.738 108.529 1.00 74.12  ? 3   LEU A CD2 1 
ATOM   25   N  N   . GLU A 1 4   ? 104.122 114.023 104.738 1.00 76.80  ? 4   GLU A N   1 
ATOM   26   C  CA  . GLU A 1 4   ? 104.530 113.678 103.385 1.00 76.80  ? 4   GLU A CA  1 
ATOM   27   C  C   . GLU A 1 4   ? 104.835 114.939 102.585 1.00 76.80  ? 4   GLU A C   1 
ATOM   28   O  O   . GLU A 1 4   ? 104.483 116.045 102.988 1.00 76.80  ? 4   GLU A O   1 
ATOM   29   C  CB  . GLU A 1 4   ? 103.436 112.868 102.705 1.00 76.80  ? 4   GLU A CB  1 
ATOM   30   C  CG  . GLU A 1 4   ? 102.892 111.762 103.577 1.00 76.80  ? 4   GLU A CG  1 
ATOM   31   C  CD  . GLU A 1 4   ? 101.590 111.191 103.059 1.00 76.80  ? 4   GLU A CD  1 
ATOM   32   O  OE1 . GLU A 1 4   ? 100.674 110.959 103.876 1.00 76.80  ? 4   GLU A OE1 1 
ATOM   33   O  OE2 . GLU A 1 4   ? 101.483 110.975 101.835 1.00 76.80  ? 4   GLU A OE2 1 
ATOM   34   N  N   . ARG A 1 5   ? 105.502 114.770 101.438 1.00 77.39  ? 5   ARG A N   1 
ATOM   35   C  CA  . ARG A 1 5   ? 105.831 115.938 100.621 1.00 77.39  ? 5   ARG A CA  1 
ATOM   36   C  C   . ARG A 1 5   ? 104.605 116.510 99.938  1.00 77.39  ? 5   ARG A C   1 
ATOM   37   O  O   . ARG A 1 5   ? 104.550 117.713 99.663  1.00 77.39  ? 5   ARG A O   1 
ATOM   38   C  CB  . ARG A 1 5   ? 106.873 115.617 99.560  1.00 77.39  ? 5   ARG A CB  1 
ATOM   39   C  CG  . ARG A 1 5   ? 108.220 115.437 100.090 1.00 77.39  ? 5   ARG A CG  1 
ATOM   40   C  CD  . ARG A 1 5   ? 108.819 116.660 100.695 1.00 77.39  ? 5   ARG A CD  1 
ATOM   41   N  NE  . ARG A 1 5   ? 109.593 117.427 99.739  1.00 77.39  ? 5   ARG A NE  1 
ATOM   42   C  CZ  . ARG A 1 5   ? 110.832 117.830 99.976  1.00 77.39  ? 5   ARG A CZ  1 
ATOM   43   N  NH1 . ARG A 1 5   ? 111.425 117.501 101.109 1.00 77.39  ? 5   ARG A NH1 1 
ATOM   44   N  NH2 . ARG A 1 5   ? 111.487 118.536 99.077  1.00 77.39  ? 5   ARG A NH2 1 
ATOM   45   N  N   . ASP A 1 6   ? 103.645 115.661 99.598  1.00 77.46  ? 6   ASP A N   1 
ATOM   46   C  CA  . ASP A 1 6   ? 102.411 116.156 99.019  1.00 77.46  ? 6   ASP A CA  1 
ATOM   47   C  C   . ASP A 1 6   ? 101.653 116.963 100.055 1.00 77.46  ? 6   ASP A C   1 
ATOM   48   O  O   . ASP A 1 6   ? 101.671 116.640 101.244 1.00 77.46  ? 6   ASP A O   1 
ATOM   49   C  CB  . ASP A 1 6   ? 101.558 115.001 98.515  1.00 77.46  ? 6   ASP A CB  1 
ATOM   50   C  CG  . ASP A 1 6   ? 102.278 114.160 97.496  1.00 77.46  ? 6   ASP A CG  1 
ATOM   51   O  OD1 . ASP A 1 6   ? 102.460 112.952 97.740  1.00 77.46  ? 6   ASP A OD1 1 
ATOM   52   O  OD2 . ASP A 1 6   ? 102.677 114.710 96.452  1.00 77.46  ? 6   ASP A OD2 1 
ATOM   53   N  N   . LEU A 1 7   ? 101.044 118.057 99.602  1.00 72.00  ? 7   LEU A N   1 
ATOM   54   C  CA  . LEU A 1 7   ? 100.260 118.894 100.496 1.00 72.00  ? 7   LEU A CA  1 
ATOM   55   C  C   . LEU A 1 7   ? 99.067  118.129 101.037 1.00 72.00  ? 7   LEU A C   1 
ATOM   56   O  O   . LEU A 1 7   ? 98.823  118.112 102.244 1.00 72.00  ? 7   LEU A O   1 
ATOM   57   C  CB  . LEU A 1 7   ? 99.807  120.150 99.766  1.00 72.00  ? 7   LEU A CB  1 
ATOM   58   C  CG  . LEU A 1 7   ? 100.890 121.124 99.325  1.00 72.00  ? 7   LEU A CG  1 
ATOM   59   C  CD1 . LEU A 1 7   ? 100.231 122.420 98.950  1.00 72.00  ? 7   LEU A CD1 1 
ATOM   60   C  CD2 . LEU A 1 7   ? 101.916 121.339 100.413 1.00 72.00  ? 7   LEU A CD2 1 
ATOM   61   N  N   . ILE A 1 8   ? 98.338  117.454 100.159 1.00 71.14  ? 8   ILE A N   1 
ATOM   62   C  CA  . ILE A 1 8   ? 97.266  116.573 100.590 1.00 71.14  ? 8   ILE A CA  1 
ATOM   63   C  C   . ILE A 1 8   ? 97.881  115.308 101.165 1.00 71.14  ? 8   ILE A C   1 
ATOM   64   O  O   . ILE A 1 8   ? 98.635  114.606 100.488 1.00 71.14  ? 8   ILE A O   1 
ATOM   65   C  CB  . ILE A 1 8   ? 96.327  116.255 99.423  1.00 71.14  ? 8   ILE A CB  1 
ATOM   66   C  CG1 . ILE A 1 8   ? 95.846  117.547 98.779  1.00 71.14  ? 8   ILE A CG1 1 
ATOM   67   C  CG2 . ILE A 1 8   ? 95.163  115.434 99.899  1.00 71.14  ? 8   ILE A CG2 1 
ATOM   68   C  CD1 . ILE A 1 8   ? 95.198  117.350 97.453  1.00 71.14  ? 8   ILE A CD1 1 
ATOM   69   N  N   . GLN A 1 9   ? 97.581  115.025 102.421 1.00 71.06  ? 9   GLN A N   1 
ATOM   70   C  CA  . GLN A 1 9   ? 98.094  113.837 103.073 1.00 71.06  ? 9   GLN A CA  1 
ATOM   71   C  C   . GLN A 1 9   ? 97.151  112.673 102.829 1.00 71.06  ? 9   GLN A C   1 
ATOM   72   O  O   . GLN A 1 9   ? 95.936  112.849 102.734 1.00 71.06  ? 9   GLN A O   1 
ATOM   73   C  CB  . GLN A 1 9   ? 98.257  114.071 104.571 1.00 71.06  ? 9   GLN A CB  1 
ATOM   74   C  CG  . GLN A 1 9   ? 98.952  115.356 104.914 1.00 71.06  ? 9   GLN A CG  1 
ATOM   75   C  CD  . GLN A 1 9   ? 100.435 115.264 104.733 1.00 71.06  ? 9   GLN A CD  1 
ATOM   76   O  OE1 . GLN A 1 9   ? 101.107 114.530 105.444 1.00 71.06  ? 9   GLN A OE1 1 
ATOM   77   N  NE2 . GLN A 1 9   ? 100.961 116.004 103.777 1.00 71.06  ? 9   GLN A NE2 1 
ATOM   78   N  N   . SER A 1 10  ? 97.718  111.477 102.721 1.00 71.51  ? 10  SER A N   1 
ATOM   79   C  CA  . SER A 1 10  ? 96.878  110.300 102.553 1.00 71.51  ? 10  SER A CA  1 
ATOM   80   C  C   . SER A 1 10  ? 96.234  109.895 103.868 1.00 71.51  ? 10  SER A C   1 
ATOM   81   O  O   . SER A 1 10  ? 95.068  109.500 103.897 1.00 71.51  ? 10  SER A O   1 
ATOM   82   C  CB  . SER A 1 10  ? 97.696  109.151 101.981 1.00 71.51  ? 10  SER A CB  1 
ATOM   83   O  OG  . SER A 1 10  ? 98.143  109.460 100.677 1.00 71.51  ? 10  SER A OG  1 
ATOM   84   N  N   . VAL A 1 11  ? 96.975  109.998 104.966 1.00 70.57  ? 11  VAL A N   1 
ATOM   85   C  CA  . VAL A 1 11  ? 96.455  109.627 106.271 1.00 70.57  ? 11  VAL A CA  1 
ATOM   86   C  C   . VAL A 1 11  ? 95.485  110.692 106.754 1.00 70.57  ? 11  VAL A C   1 
ATOM   87   O  O   . VAL A 1 11  ? 95.809  111.884 106.784 1.00 70.57  ? 11  VAL A O   1 
ATOM   88   C  CB  . VAL A 1 11  ? 97.616  109.436 107.257 1.00 70.57  ? 11  VAL A CB  1 
ATOM   89   C  CG1 . VAL A 1 11  ? 97.110  109.041 108.616 1.00 70.57  ? 11  VAL A CG1 1 
ATOM   90   C  CG2 . VAL A 1 11  ? 98.569  108.401 106.727 1.00 70.57  ? 11  VAL A CG2 1 
ATOM   91   N  N   . GLY A 1 12  ? 94.278  110.269 107.125 1.00 70.05  ? 12  GLY A N   1 
ATOM   92   C  CA  . GLY A 1 12  ? 93.264  111.161 107.647 1.00 70.05  ? 12  GLY A CA  1 
ATOM   93   C  C   . GLY A 1 12  ? 92.152  111.486 106.673 1.00 70.05  ? 12  GLY A C   1 
ATOM   94   O  O   . GLY A 1 12  ? 91.224  112.211 107.034 1.00 70.05  ? 12  GLY A O   1 
ATOM   95   N  N   . PHE A 1 13  ? 92.225  110.973 105.450 1.00 69.00  ? 13  PHE A N   1 
ATOM   96   C  CA  . PHE A 1 13  ? 91.166  111.161 104.467 1.00 69.00  ? 13  PHE A CA  1 
ATOM   97   C  C   . PHE A 1 13  ? 90.038  110.186 104.770 1.00 69.00  ? 13  PHE A C   1 
ATOM   98   O  O   . PHE A 1 13  ? 90.039  109.058 104.275 1.00 69.00  ? 13  PHE A O   1 
ATOM   99   C  CB  . PHE A 1 13  ? 91.724  110.963 103.063 1.00 69.00  ? 13  PHE A CB  1 
ATOM   100  C  CG  . PHE A 1 13  ? 90.729  111.198 101.970 1.00 69.00  ? 13  PHE A CG  1 
ATOM   101  C  CD1 . PHE A 1 13  ? 89.855  112.260 102.023 1.00 69.00  ? 13  PHE A CD1 1 
ATOM   102  C  CD2 . PHE A 1 13  ? 90.678  110.356 100.881 1.00 69.00  ? 13  PHE A CD2 1 
ATOM   103  C  CE1 . PHE A 1 13  ? 88.947  112.468 101.019 1.00 69.00  ? 13  PHE A CE1 1 
ATOM   104  C  CE2 . PHE A 1 13  ? 89.770  110.559 99.879  1.00 69.00  ? 13  PHE A CE2 1 
ATOM   105  C  CZ  . PHE A 1 13  ? 88.908  111.617 99.947  1.00 69.00  ? 13  PHE A CZ  1 
ATOM   106  N  N   . ARG A 1 14  ? 89.082  110.609 105.591 1.00 72.82  ? 14  ARG A N   1 
ATOM   107  C  CA  . ARG A 1 14  ? 88.046  109.726 106.112 1.00 72.82  ? 14  ARG A CA  1 
ATOM   108  C  C   . ARG A 1 14  ? 86.691  110.353 105.842 1.00 72.82  ? 14  ARG A C   1 
ATOM   109  O  O   . ARG A 1 14  ? 86.593  111.478 105.359 1.00 72.82  ? 14  ARG A O   1 
ATOM   110  C  CB  . ARG A 1 14  ? 88.187  109.506 107.617 1.00 72.82  ? 14  ARG A CB  1 
ATOM   111  C  CG  . ARG A 1 14  ? 89.579  109.559 108.157 1.00 72.82  ? 14  ARG A CG  1 
ATOM   112  C  CD  . ARG A 1 14  ? 89.582  109.505 109.655 1.00 72.82  ? 14  ARG A CD  1 
ATOM   113  N  NE  . ARG A 1 14  ? 89.416  108.139 110.119 1.00 72.82  ? 14  ARG A NE  1 
ATOM   114  C  CZ  . ARG A 1 14  ? 88.298  107.681 110.659 1.00 72.82  ? 14  ARG A CZ  1 
ATOM   115  N  NH1 . ARG A 1 14  ? 87.260  108.489 110.804 1.00 72.82  ? 14  ARG A NH1 1 
ATOM   116  N  NH2 . ARG A 1 14  ? 88.217  106.422 111.053 1.00 72.82  ? 14  ARG A NH2 1 
ATOM   117  N  N   . ASN A 1 15  ? 85.643  109.620 106.190 1.00 74.17  ? 15  ASN A N   1 
ATOM   118  C  CA  . ASN A 1 15  ? 84.313  110.175 106.370 1.00 74.17  ? 15  ASN A CA  1 
ATOM   119  C  C   . ASN A 1 15  ? 84.115  110.532 107.835 1.00 74.17  ? 15  ASN A C   1 
ATOM   120  O  O   . ASN A 1 15  ? 84.671  109.893 108.727 1.00 74.17  ? 15  ASN A O   1 
ATOM   121  C  CB  . ASN A 1 15  ? 83.244  109.178 105.932 1.00 74.17  ? 15  ASN A CB  1 
ATOM   122  C  CG  . ASN A 1 15  ? 83.000  109.206 104.456 1.00 74.17  ? 15  ASN A CG  1 
ATOM   123  O  OD1 . ASN A 1 15  ? 83.242  110.206 103.802 1.00 74.17  ? 15  ASN A OD1 1 
ATOM   124  N  ND2 . ASN A 1 15  ? 82.521  108.105 103.917 1.00 74.17  ? 15  ASN A ND2 1 
ATOM   125  N  N   . VAL A 1 16  ? 83.313  111.561 108.082 1.00 78.50  ? 16  VAL A N   1 
ATOM   126  C  CA  . VAL A 1 16  ? 83.102  112.092 109.423 1.00 78.50  ? 16  VAL A CA  1 
ATOM   127  C  C   . VAL A 1 16  ? 81.676  111.783 109.849 1.00 78.50  ? 16  VAL A C   1 
ATOM   128  O  O   . VAL A 1 16  ? 80.728  112.068 109.112 1.00 78.50  ? 16  VAL A O   1 
ATOM   129  C  CB  . VAL A 1 16  ? 83.383  113.602 109.479 1.00 78.50  ? 16  VAL A CB  1 
ATOM   130  C  CG1 . VAL A 1 16  ? 83.065  114.152 110.843 1.00 78.50  ? 16  VAL A CG1 1 
ATOM   131  C  CG2 . VAL A 1 16  ? 84.820  113.867 109.147 1.00 78.50  ? 16  VAL A CG2 1 
ATOM   132  N  N   . ARG A 1 17  ? 81.527  111.198 111.032 1.00 88.99  ? 17  ARG A N   1 
ATOM   133  C  CA  . ARG A 1 17  ? 80.229  110.838 111.581 1.00 88.99  ? 17  ARG A CA  1 
ATOM   134  C  C   . ARG A 1 17  ? 79.942  111.692 112.803 1.00 88.99  ? 17  ARG A C   1 
ATOM   135  O  O   . ARG A 1 17  ? 80.806  111.850 113.670 1.00 88.99  ? 17  ARG A O   1 
ATOM   136  C  CB  . ARG A 1 17  ? 80.186  109.358 111.942 1.00 88.99  ? 17  ARG A CB  1 
ATOM   137  C  CG  . ARG A 1 17  ? 80.291  108.472 110.738 1.00 88.99  ? 17  ARG A CG  1 
ATOM   138  C  CD  . ARG A 1 17  ? 80.573  107.051 111.116 1.00 88.99  ? 17  ARG A CD  1 
ATOM   139  N  NE  . ARG A 1 17  ? 80.424  106.172 109.967 1.00 88.99  ? 17  ARG A NE  1 
ATOM   140  C  CZ  . ARG A 1 17  ? 79.271  105.639 109.585 1.00 88.99  ? 17  ARG A CZ  1 
ATOM   141  N  NH1 . ARG A 1 17  ? 78.162  105.892 110.263 1.00 88.99  ? 17  ARG A NH1 1 
ATOM   142  N  NH2 . ARG A 1 17  ? 79.227  104.846 108.525 1.00 88.99  ? 17  ARG A NH2 1 
ATOM   143  N  N   . GLU A 1 18  ? 78.736  112.247 112.868 1.00 96.66  ? 18  GLU A N   1 
ATOM   144  C  CA  . GLU A 1 18  ? 78.290  113.024 114.016 1.00 96.66  ? 18  GLU A CA  1 
ATOM   145  C  C   . GLU A 1 18  ? 76.907  112.544 114.418 1.00 96.66  ? 18  GLU A C   1 
ATOM   146  O  O   . GLU A 1 18  ? 75.919  112.868 113.753 1.00 96.66  ? 18  GLU A O   1 
ATOM   147  C  CB  . GLU A 1 18  ? 78.265  114.518 113.702 1.00 96.66  ? 18  GLU A CB  1 
ATOM   148  C  CG  . GLU A 1 18  ? 79.623  115.182 113.762 1.00 96.66  ? 18  GLU A CG  1 
ATOM   149  C  CD  . GLU A 1 18  ? 79.614  116.570 113.158 1.00 96.66  ? 18  GLU A CD  1 
ATOM   150  O  OE1 . GLU A 1 18  ? 80.224  116.760 112.083 1.00 96.66  ? 18  GLU A OE1 1 
ATOM   151  O  OE2 . GLU A 1 18  ? 78.992  117.471 113.757 1.00 96.66  ? 18  GLU A OE2 1 
ATOM   152  N  N   . GLY A 1 19  ? 76.837  111.786 115.507 1.00 99.60  ? 19  GLY A N   1 
ATOM   153  C  CA  . GLY A 1 19  ? 75.567  111.246 115.939 1.00 99.60  ? 19  GLY A CA  1 
ATOM   154  C  C   . GLY A 1 19  ? 75.050  110.104 115.100 1.00 99.60  ? 19  GLY A C   1 
ATOM   155  O  O   . GLY A 1 19  ? 73.838  109.980 114.920 1.00 99.60  ? 19  GLY A O   1 
ATOM   156  N  N   . GLY A 1 20  ? 75.937  109.266 114.570 1.00 98.68  ? 20  GLY A N   1 
ATOM   157  C  CA  . GLY A 1 20  ? 75.525  108.157 113.738 1.00 98.68  ? 20  GLY A CA  1 
ATOM   158  C  C   . GLY A 1 20  ? 75.218  108.512 112.304 1.00 98.68  ? 20  GLY A C   1 
ATOM   159  O  O   . GLY A 1 20  ? 74.918  107.614 111.510 1.00 98.68  ? 20  GLY A O   1 
ATOM   160  N  N   . GLU A 1 21  ? 75.287  109.788 111.943 1.00 94.78  ? 21  GLU A N   1 
ATOM   161  C  CA  . GLU A 1 21  ? 75.054  110.245 110.583 1.00 94.78  ? 21  GLU A CA  1 
ATOM   162  C  C   . GLU A 1 21  ? 76.379  110.675 109.981 1.00 94.78  ? 21  GLU A C   1 
ATOM   163  O  O   . GLU A 1 21  ? 77.137  111.410 110.616 1.00 94.78  ? 21  GLU A O   1 
ATOM   164  C  CB  . GLU A 1 21  ? 74.073  111.416 110.557 1.00 94.78  ? 21  GLU A CB  1 
ATOM   165  C  CG  . GLU A 1 21  ? 72.677  111.079 111.015 1.00 94.78  ? 21  GLU A CG  1 
ATOM   166  C  CD  . GLU A 1 21  ? 71.952  110.175 110.047 1.00 94.78  ? 21  GLU A CD  1 
ATOM   167  O  OE1 . GLU A 1 21  ? 72.210  110.280 108.831 1.00 94.78  ? 21  GLU A OE1 1 
ATOM   168  O  OE2 . GLU A 1 21  ? 71.121  109.360 110.497 1.00 94.78  ? 21  GLU A OE2 1 
ATOM   169  N  N   . ILE A 1 22  ? 76.657  110.225 108.760 1.00 83.92  ? 22  ILE A N   1 
ATOM   170  C  CA  . ILE A 1 22  ? 77.804  110.752 108.038 1.00 83.92  ? 22  ILE A CA  1 
ATOM   171  C  C   . ILE A 1 22  ? 77.467  112.143 107.532 1.00 83.92  ? 22  ILE A C   1 
ATOM   172  O  O   . ILE A 1 22  ? 76.624  112.310 106.643 1.00 83.92  ? 22  ILE A O   1 
ATOM   173  C  CB  . ILE A 1 22  ? 78.201  109.824 106.886 1.00 83.92  ? 22  ILE A CB  1 
ATOM   174  C  CG1 . ILE A 1 22  ? 78.437  108.412 107.400 1.00 83.92  ? 22  ILE A CG1 1 
ATOM   175  C  CG2 . ILE A 1 22  ? 79.450  110.338 106.222 1.00 83.92  ? 22  ILE A CG2 1 
ATOM   176  C  CD1 . ILE A 1 22  ? 78.765  107.436 106.316 1.00 83.92  ? 22  ILE A CD1 1 
ATOM   177  N  N   . THR A 1 23  ? 78.118  113.152 108.103 1.00 80.96  ? 23  THR A N   1 
ATOM   178  C  CA  . THR A 1 23  ? 77.830  114.533 107.766 1.00 80.96  ? 23  THR A CA  1 
ATOM   179  C  C   . THR A 1 23  ? 78.762  115.114 106.721 1.00 80.96  ? 23  THR A C   1 
ATOM   180  O  O   . THR A 1 23  ? 78.431  116.143 106.132 1.00 80.96  ? 23  THR A O   1 
ATOM   181  C  CB  . THR A 1 23  ? 77.894  115.411 109.020 1.00 80.96  ? 23  THR A CB  1 
ATOM   182  O  OG1 . THR A 1 23  ? 79.200  115.321 109.595 1.00 80.96  ? 23  THR A OG1 1 
ATOM   183  C  CG2 . THR A 1 23  ? 76.877  114.952 110.035 1.00 80.96  ? 23  THR A CG2 1 
ATOM   184  N  N   . GLY A 1 24  ? 79.902  114.486 106.476 1.00 74.66  ? 24  GLY A N   1 
ATOM   185  C  CA  . GLY A 1 24  ? 80.853  115.013 105.522 1.00 74.66  ? 24  GLY A CA  1 
ATOM   186  C  C   . GLY A 1 24  ? 82.098  114.158 105.520 1.00 74.66  ? 24  GLY A C   1 
ATOM   187  O  O   . GLY A 1 24  ? 82.103  113.052 106.053 1.00 74.66  ? 24  GLY A O   1 
ATOM   188  N  N   . PHE A 1 25  ? 83.146  114.686 104.913 1.00 69.23  ? 25  PHE A N   1 
ATOM   189  C  CA  . PHE A 1 25  ? 84.426  114.008 104.893 1.00 69.23  ? 25  PHE A CA  1 
ATOM   190  C  C   . PHE A 1 25  ? 85.508  114.991 105.301 1.00 69.23  ? 25  PHE A C   1 
ATOM   191  O  O   . PHE A 1 25  ? 85.311  116.204 105.287 1.00 69.23  ? 25  PHE A O   1 
ATOM   192  C  CB  . PHE A 1 25  ? 84.720  113.383 103.519 1.00 69.23  ? 25  PHE A CB  1 
ATOM   193  C  CG  . PHE A 1 25  ? 84.972  114.375 102.429 1.00 69.23  ? 25  PHE A CG  1 
ATOM   194  C  CD1 . PHE A 1 25  ? 83.921  114.963 101.761 1.00 69.23  ? 25  PHE A CD1 1 
ATOM   195  C  CD2 . PHE A 1 25  ? 86.261  114.688 102.043 1.00 69.23  ? 25  PHE A CD2 1 
ATOM   196  C  CE1 . PHE A 1 25  ? 84.150  115.860 100.761 1.00 69.23  ? 25  PHE A CE1 1 
ATOM   197  C  CE2 . PHE A 1 25  ? 86.490  115.588 101.044 1.00 69.23  ? 25  PHE A CE2 1 
ATOM   198  C  CZ  . PHE A 1 25  ? 85.435  116.170 100.400 1.00 69.23  ? 25  PHE A CZ  1 
ATOM   199  N  N   . GLN A 1 26  ? 86.660  114.453 105.675 1.00 69.78  ? 26  GLN A N   1 
ATOM   200  C  CA  . GLN A 1 26  ? 87.778  115.273 106.098 1.00 69.78  ? 26  GLN A CA  1 
ATOM   201  C  C   . GLN A 1 26  ? 89.042  114.804 105.406 1.00 69.78  ? 26  GLN A C   1 
ATOM   202  O  O   . GLN A 1 26  ? 89.108  113.696 104.877 1.00 69.78  ? 26  GLN A O   1 
ATOM   203  C  CB  . GLN A 1 26  ? 87.972  115.231 107.610 1.00 69.78  ? 26  GLN A CB  1 
ATOM   204  C  CG  . GLN A 1 26  ? 88.431  113.898 108.111 1.00 69.78  ? 26  GLN A CG  1 
ATOM   205  C  CD  . GLN A 1 26  ? 89.005  113.969 109.491 1.00 69.78  ? 26  GLN A CD  1 
ATOM   206  O  OE1 . GLN A 1 26  ? 88.331  114.369 110.432 1.00 69.78  ? 26  GLN A OE1 1 
ATOM   207  N  NE2 . GLN A 1 26  ? 90.257  113.576 109.627 1.00 69.78  ? 26  GLN A NE2 1 
ATOM   208  N  N   . PHE A 1 27  ? 90.043  115.677 105.401 1.00 66.30  ? 27  PHE A N   1 
ATOM   209  C  CA  . PHE A 1 27  ? 91.379  115.334 104.944 1.00 66.30  ? 27  PHE A CA  1 
ATOM   210  C  C   . PHE A 1 27  ? 92.354  116.289 105.605 1.00 66.30  ? 27  PHE A C   1 
ATOM   211  O  O   . PHE A 1 27  ? 91.960  117.311 106.163 1.00 66.30  ? 27  PHE A O   1 
ATOM   212  C  CB  . PHE A 1 27  ? 91.510  115.372 103.413 1.00 66.30  ? 27  PHE A CB  1 
ATOM   213  C  CG  . PHE A 1 27  ? 91.168  116.691 102.791 1.00 66.30  ? 27  PHE A CG  1 
ATOM   214  C  CD1 . PHE A 1 27  ? 89.862  117.012 102.487 1.00 66.30  ? 27  PHE A CD1 1 
ATOM   215  C  CD2 . PHE A 1 27  ? 92.158  117.593 102.467 1.00 66.30  ? 27  PHE A CD2 1 
ATOM   216  C  CE1 . PHE A 1 27  ? 89.552  118.207 101.914 1.00 66.30  ? 27  PHE A CE1 1 
ATOM   217  C  CE2 . PHE A 1 27  ? 91.845  118.791 101.888 1.00 66.30  ? 27  PHE A CE2 1 
ATOM   218  C  CZ  . PHE A 1 27  ? 90.545  119.095 101.613 1.00 66.30  ? 27  PHE A CZ  1 
ATOM   219  N  N   . ARG A 1 28  ? 93.631  115.942 105.552 1.00 67.94  ? 28  ARG A N   1 
ATOM   220  C  CA  . ARG A 1 28  ? 94.675  116.718 106.201 1.00 67.94  ? 28  ARG A CA  1 
ATOM   221  C  C   . ARG A 1 28  ? 95.587  117.350 105.163 1.00 67.94  ? 28  ARG A C   1 
ATOM   222  O  O   . ARG A 1 28  ? 95.934  116.720 104.164 1.00 67.94  ? 28  ARG A O   1 
ATOM   223  C  CB  . ARG A 1 28  ? 95.485  115.848 107.157 1.00 67.94  ? 28  ARG A CB  1 
ATOM   224  C  CG  . ARG A 1 28  ? 94.713  115.424 108.382 1.00 67.94  ? 28  ARG A CG  1 
ATOM   225  C  CD  . ARG A 1 28  ? 95.366  114.259 109.079 1.00 67.94  ? 28  ARG A CD  1 
ATOM   226  N  NE  . ARG A 1 28  ? 96.646  114.617 109.671 1.00 67.94  ? 28  ARG A NE  1 
ATOM   227  C  CZ  . ARG A 1 28  ? 97.804  114.076 109.320 1.00 67.94  ? 28  ARG A CZ  1 
ATOM   228  N  NH1 . ARG A 1 28  ? 97.845  113.151 108.380 1.00 67.94  ? 28  ARG A NH1 1 
ATOM   229  N  NH2 . ARG A 1 28  ? 98.920  114.462 109.909 1.00 67.94  ? 28  ARG A NH2 1 
ATOM   230  N  N   . VAL A 1 29  ? 95.962  118.604 105.399 1.00 68.29  ? 29  VAL A N   1 
ATOM   231  C  CA  . VAL A 1 29  ? 96.788  119.380 104.483 1.00 68.29  ? 29  VAL A CA  1 
ATOM   232  C  C   . VAL A 1 29  ? 98.058  119.797 105.204 1.00 68.29  ? 29  VAL A C   1 
ATOM   233  O  O   . VAL A 1 29  ? 97.997  120.357 106.301 1.00 68.29  ? 29  VAL A O   1 
ATOM   234  C  CB  . VAL A 1 29  ? 96.057  120.626 103.954 1.00 68.29  ? 29  VAL A CB  1 
ATOM   235  C  CG1 . VAL A 1 29  ? 96.857  121.272 102.857 1.00 68.29  ? 29  VAL A CG1 1 
ATOM   236  C  CG2 . VAL A 1 29  ? 94.710  120.272 103.435 1.00 68.29  ? 29  VAL A CG2 1 
ATOM   237  N  N   . ARG A 1 30  ? 99.200  119.534 104.584 1.00 72.18  ? 30  ARG A N   1 
ATOM   238  C  CA  . ARG A 1 30  ? 100.457 120.089 105.053 1.00 72.18  ? 30  ARG A CA  1 
ATOM   239  C  C   . ARG A 1 30  ? 100.535 121.565 104.704 1.00 72.18  ? 30  ARG A C   1 
ATOM   240  O  O   . ARG A 1 30  ? 100.031 122.003 103.671 1.00 72.18  ? 30  ARG A O   1 
ATOM   241  C  CB  . ARG A 1 30  ? 101.626 119.350 104.419 1.00 72.18  ? 30  ARG A CB  1 
ATOM   242  C  CG  . ARG A 1 30  ? 102.907 119.426 105.191 1.00 72.18  ? 30  ARG A CG  1 
ATOM   243  C  CD  . ARG A 1 30  ? 104.062 118.967 104.347 1.00 72.18  ? 30  ARG A CD  1 
ATOM   244  N  NE  . ARG A 1 30  ? 104.801 120.086 103.790 1.00 72.18  ? 30  ARG A NE  1 
ATOM   245  C  CZ  . ARG A 1 30  ? 105.301 120.111 102.564 1.00 72.18  ? 30  ARG A CZ  1 
ATOM   246  N  NH1 . ARG A 1 30  ? 105.135 119.080 101.763 1.00 72.18  ? 30  ARG A NH1 1 
ATOM   247  N  NH2 . ARG A 1 30  ? 105.961 121.172 102.140 1.00 72.18  ? 30  ARG A NH2 1 
ATOM   248  N  N   . MET A 1 31  ? 101.164 122.333 105.579 1.00 74.04  ? 31  MET A N   1 
ATOM   249  C  CA  . MET A 1 31  ? 101.352 123.754 105.338 1.00 74.04  ? 31  MET A CA  1 
ATOM   250  C  C   . MET A 1 31  ? 102.333 123.954 104.189 1.00 74.04  ? 31  MET A C   1 
ATOM   251  O  O   . MET A 1 31  ? 103.471 123.477 104.269 1.00 74.04  ? 31  MET A O   1 
ATOM   252  C  CB  . MET A 1 31  ? 101.854 124.442 106.599 1.00 74.04  ? 31  MET A CB  1 
ATOM   253  C  CG  . MET A 1 31  ? 102.401 125.829 106.379 1.00 74.04  ? 31  MET A CG  1 
ATOM   254  S  SD  . MET A 1 31  ? 101.170 127.031 105.870 1.00 74.04  ? 31  MET A SD  1 
ATOM   255  C  CE  . MET A 1 31  ? 100.616 127.625 107.451 1.00 74.04  ? 31  MET A CE  1 
ATOM   256  N  N   . PRO A 1 32  ? 101.932 124.616 103.103 1.00 73.21  ? 32  PRO A N   1 
ATOM   257  C  CA  . PRO A 1 32  ? 102.843 124.730 101.959 1.00 73.21  ? 32  PRO A CA  1 
ATOM   258  C  C   . PRO A 1 32  ? 103.944 125.742 102.170 1.00 73.21  ? 32  PRO A C   1 
ATOM   259  O  O   . PRO A 1 32  ? 104.987 125.655 101.515 1.00 73.21  ? 32  PRO A O   1 
ATOM   260  C  CB  . PRO A 1 32  ? 101.907 125.146 100.825 1.00 73.21  ? 32  PRO A CB  1 
ATOM   261  C  CG  . PRO A 1 32  ? 100.817 125.850 101.498 1.00 73.21  ? 32  PRO A CG  1 
ATOM   262  C  CD  . PRO A 1 32  ? 100.608 125.174 102.801 1.00 73.21  ? 32  PRO A CD  1 
ATOM   263  N  N   . SER A 1 33  ? 103.743 126.704 103.062 1.00 75.51  ? 33  SER A N   1 
ATOM   264  C  CA  . SER A 1 33  ? 104.720 127.753 103.268 1.00 75.51  ? 33  SER A CA  1 
ATOM   265  C  C   . SER A 1 33  ? 105.902 127.232 104.078 1.00 75.51  ? 33  SER A C   1 
ATOM   266  O  O   . SER A 1 33  ? 105.932 126.089 104.533 1.00 75.51  ? 33  SER A O   1 
ATOM   267  C  CB  . SER A 1 33  ? 104.077 128.940 103.972 1.00 75.51  ? 33  SER A CB  1 
ATOM   268  O  OG  . SER A 1 33  ? 105.060 129.811 104.487 1.00 75.51  ? 33  SER A OG  1 
ATOM   269  N  N   . TYR A 1 34  ? 106.894 128.095 104.259 1.00 77.21  ? 34  TYR A N   1 
ATOM   270  C  CA  . TYR A 1 34  ? 108.066 127.741 105.042 1.00 77.21  ? 34  TYR A CA  1 
ATOM   271  C  C   . TYR A 1 34  ? 107.876 128.017 106.520 1.00 77.21  ? 34  TYR A C   1 
ATOM   272  O  O   . TYR A 1 34  ? 108.751 127.687 107.318 1.00 77.21  ? 34  TYR A O   1 
ATOM   273  C  CB  . TYR A 1 34  ? 109.299 128.480 104.531 1.00 77.21  ? 34  TYR A CB  1 
ATOM   274  C  CG  . TYR A 1 34  ? 109.068 129.928 104.226 1.00 77.21  ? 34  TYR A CG  1 
ATOM   275  C  CD1 . TYR A 1 34  ? 109.130 130.881 105.224 1.00 77.21  ? 34  TYR A CD1 1 
ATOM   276  C  CD2 . TYR A 1 34  ? 108.805 130.347 102.935 1.00 77.21  ? 34  TYR A CD2 1 
ATOM   277  C  CE1 . TYR A 1 34  ? 108.919 132.201 104.952 1.00 77.21  ? 34  TYR A CE1 1 
ATOM   278  C  CE2 . TYR A 1 34  ? 108.594 131.665 102.654 1.00 77.21  ? 34  TYR A CE2 1 
ATOM   279  C  CZ  . TYR A 1 34  ? 108.655 132.588 103.666 1.00 77.21  ? 34  TYR A CZ  1 
ATOM   280  O  OH  . TYR A 1 34  ? 108.450 133.911 103.387 1.00 77.21  ? 34  TYR A OH  1 
ATOM   281  N  N   . ARG A 1 35  ? 106.758 128.618 106.900 1.00 74.40  ? 35  ARG A N   1 
ATOM   282  C  CA  . ARG A 1 35  ? 106.473 128.887 108.296 1.00 74.40  ? 35  ARG A CA  1 
ATOM   283  C  C   . ARG A 1 35  ? 105.038 128.499 108.579 1.00 74.40  ? 35  ARG A C   1 
ATOM   284  O  O   . ARG A 1 35  ? 104.235 128.348 107.660 1.00 74.40  ? 35  ARG A O   1 
ATOM   285  C  CB  . ARG A 1 35  ? 106.690 130.360 108.642 1.00 74.40  ? 35  ARG A CB  1 
ATOM   286  C  CG  . ARG A 1 35  ? 105.587 131.257 108.148 1.00 74.40  ? 35  ARG A CG  1 
ATOM   287  C  CD  . ARG A 1 35  ? 105.896 132.692 108.403 1.00 74.40  ? 35  ARG A CD  1 
ATOM   288  N  NE  . ARG A 1 35  ? 104.990 133.582 107.696 1.00 74.40  ? 35  ARG A NE  1 
ATOM   289  C  CZ  . ARG A 1 35  ? 104.133 134.394 108.293 1.00 74.40  ? 35  ARG A CZ  1 
ATOM   290  N  NH1 . ARG A 1 35  ? 104.066 134.428 109.610 1.00 74.40  ? 35  ARG A NH1 1 
ATOM   291  N  NH2 . ARG A 1 35  ? 103.352 135.176 107.572 1.00 74.40  ? 35  ARG A NH2 1 
ATOM   292  N  N   . GLY A 1 36  ? 104.737 128.294 109.853 1.00 73.88  ? 36  GLY A N   1 
ATOM   293  C  CA  . GLY A 1 36  ? 103.358 128.300 110.280 1.00 73.88  ? 36  GLY A CA  1 
ATOM   294  C  C   . GLY A 1 36  ? 102.913 129.708 110.612 1.00 73.88  ? 36  GLY A C   1 
ATOM   295  O  O   . GLY A 1 36  ? 103.699 130.540 111.050 1.00 73.88  ? 36  GLY A O   1 
ATOM   296  N  N   . MET A 1 37  ? 101.637 129.988 110.396 1.00 74.47  ? 37  MET A N   1 
ATOM   297  C  CA  . MET A 1 37  ? 101.163 131.345 110.583 1.00 74.47  ? 37  MET A CA  1 
ATOM   298  C  C   . MET A 1 37  ? 99.898  131.338 111.417 1.00 74.47  ? 37  MET A C   1 
ATOM   299  O  O   . MET A 1 37  ? 99.340  130.289 111.735 1.00 74.47  ? 37  MET A O   1 
ATOM   300  C  CB  . MET A 1 37  ? 100.918 132.044 109.247 1.00 74.47  ? 37  MET A CB  1 
ATOM   301  C  CG  . MET A 1 37  ? 100.168 131.218 108.244 1.00 74.47  ? 37  MET A CG  1 
ATOM   302  S  SD  . MET A 1 37  ? 100.248 131.955 106.611 1.00 74.47  ? 37  MET A SD  1 
ATOM   303  C  CE  . MET A 1 37  ? 101.887 131.464 106.120 1.00 74.47  ? 37  MET A CE  1 
ATOM   304  N  N   . ALA A 1 38  ? 99.466  132.537 111.786 1.00 72.90  ? 38  ALA A N   1 
ATOM   305  C  CA  . ALA A 1 38  ? 98.202  132.694 112.481 1.00 72.90  ? 38  ALA A CA  1 
ATOM   306  C  C   . ALA A 1 38  ? 97.055  132.334 111.555 1.00 72.90  ? 38  ALA A C   1 
ATOM   307  O  O   . ALA A 1 38  ? 97.138  132.513 110.340 1.00 72.90  ? 38  ALA A O   1 
ATOM   308  C  CB  . ALA A 1 38  ? 98.047  134.123 112.979 1.00 72.90  ? 38  ALA A CB  1 
ATOM   309  N  N   . ALA A 1 39  ? 95.979  131.817 112.137 1.00 71.77  ? 39  ALA A N   1 
ATOM   310  C  CA  . ALA A 1 39  ? 94.908  131.240 111.341 1.00 71.77  ? 39  ALA A CA  1 
ATOM   311  C  C   . ALA A 1 39  ? 94.045  132.290 110.670 1.00 71.77  ? 39  ALA A C   1 
ATOM   312  O  O   . ALA A 1 39  ? 93.268  131.951 109.778 1.00 71.77  ? 39  ALA A O   1 
ATOM   313  C  CB  . ALA A 1 39  ? 94.052  130.346 112.218 1.00 71.77  ? 39  ALA A CB  1 
ATOM   314  N  N   . SER A 1 40  ? 94.161  133.553 111.065 1.00 72.60  ? 40  SER A N   1 
ATOM   315  C  CA  . SER A 1 40  ? 93.408  134.601 110.397 1.00 72.60  ? 40  SER A CA  1 
ATOM   316  C  C   . SER A 1 40  ? 94.013  134.979 109.056 1.00 72.60  ? 40  SER A C   1 
ATOM   317  O  O   . SER A 1 40  ? 93.367  135.679 108.275 1.00 72.60  ? 40  SER A O   1 
ATOM   318  C  CB  . SER A 1 40  ? 93.312  135.820 111.303 1.00 72.60  ? 40  SER A CB  1 
ATOM   319  O  OG  . SER A 1 40  ? 94.589  136.363 111.547 1.00 72.60  ? 40  SER A OG  1 
ATOM   320  N  N   . LEU A 1 41  ? 95.232  134.530 108.772 1.00 73.51  ? 41  LEU A N   1 
ATOM   321  C  CA  . LEU A 1 41  ? 95.845  134.754 107.474 1.00 73.51  ? 41  LEU A CA  1 
ATOM   322  C  C   . LEU A 1 41  ? 95.373  133.759 106.430 1.00 73.51  ? 41  LEU A C   1 
ATOM   323  O  O   . LEU A 1 41  ? 95.720  133.902 105.256 1.00 73.51  ? 41  LEU A O   1 
ATOM   324  C  CB  . LEU A 1 41  ? 97.358  134.682 107.599 1.00 73.51  ? 41  LEU A CB  1 
ATOM   325  C  CG  . LEU A 1 41  ? 97.961  135.790 108.442 1.00 73.51  ? 41  LEU A CG  1 
ATOM   326  C  CD1 . LEU A 1 41  ? 99.371  135.439 108.810 1.00 73.51  ? 41  LEU A CD1 1 
ATOM   327  C  CD2 . LEU A 1 41  ? 97.919  137.072 107.665 1.00 73.51  ? 41  LEU A CD2 1 
ATOM   328  N  N   . ILE A 1 42  ? 94.603  132.754 106.830 1.00 72.26  ? 42  ILE A N   1 
ATOM   329  C  CA  . ILE A 1 42  ? 94.036  131.811 105.882 1.00 72.26  ? 42  ILE A CA  1 
ATOM   330  C  C   . ILE A 1 42  ? 92.912  132.487 105.116 1.00 72.26  ? 42  ILE A C   1 
ATOM   331  O  O   . ILE A 1 42  ? 92.004  133.077 105.708 1.00 72.26  ? 42  ILE A O   1 
ATOM   332  C  CB  . ILE A 1 42  ? 93.542  130.566 106.625 1.00 72.26  ? 42  ILE A CB  1 
ATOM   333  C  CG1 . ILE A 1 42  ? 94.725  129.751 107.123 1.00 72.26  ? 42  ILE A CG1 1 
ATOM   334  C  CG2 . ILE A 1 42  ? 92.674  129.744 105.747 1.00 72.26  ? 42  ILE A CG2 1 
ATOM   335  C  CD1 . ILE A 1 42  ? 94.368  128.786 108.201 1.00 72.26  ? 42  ILE A CD1 1 
ATOM   336  N  N   . ASP A 1 43  ? 92.966  132.408 103.792 1.00 76.25  ? 43  ASP A N   1 
ATOM   337  C  CA  . ASP A 1 43  ? 91.950  133.010 102.950 1.00 76.25  ? 43  ASP A CA  1 
ATOM   338  C  C   . ASP A 1 43  ? 91.015  131.976 102.338 1.00 76.25  ? 43  ASP A C   1 
ATOM   339  O  O   . ASP A 1 43  ? 90.233  132.311 101.447 1.00 76.25  ? 43  ASP A O   1 
ATOM   340  C  CB  . ASP A 1 43  ? 92.616  133.847 101.864 1.00 76.25  ? 43  ASP A CB  1 
ATOM   341  C  CG  . ASP A 1 43  ? 91.789  135.036 101.463 1.00 76.25  ? 43  ASP A CG  1 
ATOM   342  O  OD1 . ASP A 1 43  ? 91.699  135.984 102.265 1.00 76.25  ? 43  ASP A OD1 1 
ATOM   343  O  OD2 . ASP A 1 43  ? 91.236  135.037 100.346 1.00 76.25  ? 43  ASP A OD2 1 
ATOM   344  N  N   . GLY A 1 44  ? 91.072  130.736 102.795 1.00 75.11  ? 44  GLY A N   1 
ATOM   345  C  CA  . GLY A 1 44  ? 90.118  129.718 102.410 1.00 75.11  ? 44  GLY A CA  1 
ATOM   346  C  C   . GLY A 1 44  ? 90.771  128.571 101.662 1.00 75.11  ? 44  GLY A C   1 
ATOM   347  O  O   . GLY A 1 44  ? 91.928  128.625 101.253 1.00 75.11  ? 44  GLY A O   1 
ATOM   348  N  N   . ILE A 1 45  ? 89.994  127.506 101.496 1.00 72.19  ? 45  ILE A N   1 
ATOM   349  C  CA  . ILE A 1 45  ? 90.392  126.374 100.671 1.00 72.19  ? 45  ILE A CA  1 
ATOM   350  C  C   . ILE A 1 45  ? 89.191  125.932 99.845  1.00 72.19  ? 45  ILE A C   1 
ATOM   351  O  O   . ILE A 1 45  ? 88.082  125.782 100.369 1.00 72.19  ? 45  ILE A O   1 
ATOM   352  C  CB  . ILE A 1 45  ? 90.989  125.215 101.505 1.00 72.19  ? 45  ILE A CB  1 
ATOM   353  C  CG1 . ILE A 1 45  ? 91.487  124.094 100.603 1.00 72.19  ? 45  ILE A CG1 1 
ATOM   354  C  CG2 . ILE A 1 45  ? 90.038  124.659 102.556 1.00 72.19  ? 45  ILE A CG2 1 
ATOM   355  C  CD1 . ILE A 1 45  ? 92.338  123.101 101.318 1.00 72.19  ? 45  ILE A CD1 1 
ATOM   356  N  N   . GLY A 1 46  ? 89.391  125.791 98.541  1.00 72.80  ? 46  GLY A N   1 
ATOM   357  C  CA  . GLY A 1 46  ? 88.354  125.297 97.661  1.00 72.80  ? 46  GLY A CA  1 
ATOM   358  C  C   . GLY A 1 46  ? 88.645  123.847 97.336  1.00 72.80  ? 46  GLY A C   1 
ATOM   359  O  O   . GLY A 1 46  ? 89.752  123.507 96.933  1.00 72.80  ? 46  GLY A O   1 
ATOM   360  N  N   . VAL A 1 47  ? 87.647  122.999 97.529  1.00 72.99  ? 47  VAL A N   1 
ATOM   361  C  CA  . VAL A 1 47  ? 87.806  121.557 97.421  1.00 72.99  ? 47  VAL A CA  1 
ATOM   362  C  C   . VAL A 1 47  ? 86.947  121.070 96.269  1.00 72.99  ? 47  VAL A C   1 
ATOM   363  O  O   . VAL A 1 47  ? 85.770  121.426 96.175  1.00 72.99  ? 47  VAL A O   1 
ATOM   364  C  CB  . VAL A 1 47  ? 87.419  120.858 98.734  1.00 72.99  ? 47  VAL A CB  1 
ATOM   365  C  CG1 . VAL A 1 47  ? 87.528  119.367 98.607  1.00 72.99  ? 47  VAL A CG1 1 
ATOM   366  C  CG2 . VAL A 1 47  ? 88.295  121.351 99.854  1.00 72.99  ? 47  VAL A CG2 1 
ATOM   367  N  N   . ARG A 1 48  ? 87.534  120.265 95.391  1.00 78.25  ? 48  ARG A N   1 
ATOM   368  C  CA  . ARG A 1 48  ? 86.805  119.728 94.255  1.00 78.25  ? 48  ARG A CA  1 
ATOM   369  C  C   . ARG A 1 48  ? 87.178  118.273 94.035  1.00 78.25  ? 48  ARG A C   1 
ATOM   370  O  O   . ARG A 1 48  ? 88.358  117.942 93.916  1.00 78.25  ? 48  ARG A O   1 
ATOM   371  C  CB  . ARG A 1 48  ? 87.090  120.545 92.996  1.00 78.25  ? 48  ARG A CB  1 
ATOM   372  C  CG  . ARG A 1 48  ? 86.774  119.828 91.725  1.00 78.25  ? 48  ARG A CG  1 
ATOM   373  C  CD  . ARG A 1 48  ? 86.723  120.773 90.553  1.00 78.25  ? 48  ARG A CD  1 
ATOM   374  N  NE  . ARG A 1 48  ? 86.606  120.043 89.295  1.00 78.25  ? 48  ARG A NE  1 
ATOM   375  C  CZ  . ARG A 1 48  ? 85.463  119.584 88.797  1.00 78.25  ? 48  ARG A CZ  1 
ATOM   376  N  NH1 . ARG A 1 48  ? 84.322  119.782 89.443  1.00 78.25  ? 48  ARG A NH1 1 
ATOM   377  N  NH2 . ARG A 1 48  ? 85.459  118.928 87.646  1.00 78.25  ? 48  ARG A NH2 1 
ATOM   378  N  N   . ILE A 1 49  ? 86.171  117.411 94.006  1.00 75.60  ? 49  ILE A N   1 
ATOM   379  C  CA  . ILE A 1 49  ? 86.290  116.044 93.520  1.00 75.60  ? 49  ILE A CA  1 
ATOM   380  C  C   . ILE A 1 49  ? 85.315  115.917 92.358  1.00 75.60  ? 49  ILE A C   1 
ATOM   381  O  O   . ILE A 1 49  ? 84.119  116.150 92.540  1.00 75.60  ? 49  ILE A O   1 
ATOM   382  C  CB  . ILE A 1 49  ? 85.981  115.000 94.605  1.00 75.60  ? 49  ILE A CB  1 
ATOM   383  C  CG1 . ILE A 1 49  ? 86.952  115.145 95.767  1.00 75.60  ? 49  ILE A CG1 1 
ATOM   384  C  CG2 . ILE A 1 49  ? 86.066  113.615 94.029  1.00 75.60  ? 49  ILE A CG2 1 
ATOM   385  C  CD1 . ILE A 1 49  ? 86.717  114.182 96.876  1.00 75.60  ? 49  ILE A CD1 1 
ATOM   386  N  N   . PRO A 1 50  ? 85.775  115.569 91.155  1.00 78.89  ? 50  PRO A N   1 
ATOM   387  C  CA  . PRO A 1 50  ? 84.921  115.653 89.960  1.00 78.89  ? 50  PRO A CA  1 
ATOM   388  C  C   . PRO A 1 50  ? 83.743  114.693 89.977  1.00 78.89  ? 50  PRO A C   1 
ATOM   389  O  O   . PRO A 1 50  ? 83.907  113.475 90.067  1.00 78.89  ? 50  PRO A O   1 
ATOM   390  C  CB  . PRO A 1 50  ? 85.889  115.321 88.820  1.00 78.89  ? 50  PRO A CB  1 
ATOM   391  C  CG  . PRO A 1 50  ? 87.009  114.615 89.465  1.00 78.89  ? 50  PRO A CG  1 
ATOM   392  C  CD  . PRO A 1 50  ? 87.161  115.243 90.799  1.00 78.89  ? 50  PRO A CD  1 
ATOM   393  N  N   . GLY A 1 51  ? 82.545  115.263 89.902  1.00 79.67  ? 51  GLY A N   1 
ATOM   394  C  CA  . GLY A 1 51  ? 81.317  114.510 89.973  1.00 79.67  ? 51  GLY A CA  1 
ATOM   395  C  C   . GLY A 1 51  ? 80.691  114.428 91.344  1.00 79.67  ? 51  GLY A C   1 
ATOM   396  O  O   . GLY A 1 51  ? 79.483  114.186 91.438  1.00 79.67  ? 51  GLY A O   1 
ATOM   397  N  N   . LEU A 1 52  ? 81.459  114.636 92.407  1.00 77.86  ? 52  LEU A N   1 
ATOM   398  C  CA  . LEU A 1 52  ? 80.960  114.458 93.762  1.00 77.86  ? 52  LEU A CA  1 
ATOM   399  C  C   . LEU A 1 52  ? 80.940  115.749 94.562  1.00 77.86  ? 52  LEU A C   1 
ATOM   400  O  O   . LEU A 1 52  ? 79.906  116.094 95.140  1.00 77.86  ? 52  LEU A O   1 
ATOM   401  C  CB  . LEU A 1 52  ? 81.808  113.407 94.487  1.00 77.86  ? 52  LEU A CB  1 
ATOM   402  C  CG  . LEU A 1 52  ? 81.802  112.009 93.877  1.00 77.86  ? 52  LEU A CG  1 
ATOM   403  C  CD1 . LEU A 1 52  ? 82.736  111.109 94.639  1.00 77.86  ? 52  LEU A CD1 1 
ATOM   404  C  CD2 . LEU A 1 52  ? 80.409  111.438 93.878  1.00 77.86  ? 52  LEU A CD2 1 
ATOM   405  N  N   . VAL A 1 53  ? 82.060  116.464 94.635  1.00 77.22  ? 53  VAL A N   1 
ATOM   406  C  CA  . VAL A 1 53  ? 82.197  117.634 95.492  1.00 77.22  ? 53  VAL A CA  1 
ATOM   407  C  C   . VAL A 1 53  ? 82.704  118.795 94.653  1.00 77.22  ? 53  VAL A C   1 
ATOM   408  O  O   . VAL A 1 53  ? 83.641  118.647 93.866  1.00 77.22  ? 53  VAL A O   1 
ATOM   409  C  CB  . VAL A 1 53  ? 83.173  117.381 96.667  1.00 77.22  ? 53  VAL A CB  1 
ATOM   410  C  CG1 . VAL A 1 53  ? 83.184  118.544 97.624  1.00 77.22  ? 53  VAL A CG1 1 
ATOM   411  C  CG2 . VAL A 1 53  ? 82.851  116.109 97.404  1.00 77.22  ? 53  VAL A CG2 1 
ATOM   412  N  N   . ASP A 1 54  ? 82.089  119.963 94.825  1.00 81.76  ? 54  ASP A N   1 
ATOM   413  C  CA  . ASP A 1 54  ? 82.671  121.201 94.305  1.00 81.76  ? 54  ASP A CA  1 
ATOM   414  C  C   . ASP A 1 54  ? 82.197  122.333 95.217  1.00 81.76  ? 54  ASP A C   1 
ATOM   415  O  O   . ASP A 1 54  ? 81.093  122.849 95.045  1.00 81.76  ? 54  ASP A O   1 
ATOM   416  C  CB  . ASP A 1 54  ? 82.275  121.449 92.863  1.00 81.76  ? 54  ASP A CB  1 
ATOM   417  C  CG  . ASP A 1 54  ? 83.229  122.381 92.146  1.00 81.76  ? 54  ASP A CG  1 
ATOM   418  O  OD1 . ASP A 1 54  ? 83.979  123.116 92.817  1.00 81.76  ? 54  ASP A OD1 1 
ATOM   419  O  OD2 . ASP A 1 54  ? 83.237  122.376 90.897  1.00 81.76  ? 54  ASP A OD2 1 
ATOM   420  N  N   . VAL A 1 55  ? 83.041  122.711 96.174  1.00 76.35  ? 55  VAL A N   1 
ATOM   421  C  CA  . VAL A 1 55  ? 82.699  123.746 97.136  1.00 76.35  ? 55  VAL A CA  1 
ATOM   422  C  C   . VAL A 1 55  ? 83.652  124.917 96.969  1.00 76.35  ? 55  VAL A C   1 
ATOM   423  O  O   . VAL A 1 55  ? 84.752  124.791 96.429  1.00 76.35  ? 55  VAL A O   1 
ATOM   424  C  CB  . VAL A 1 55  ? 82.718  123.237 98.591  1.00 76.35  ? 55  VAL A CB  1 
ATOM   425  C  CG1 . VAL A 1 55  ? 81.722  122.125 98.761  1.00 76.35  ? 55  VAL A CG1 1 
ATOM   426  C  CG2 . VAL A 1 55  ? 84.098  122.773 98.978  1.00 76.35  ? 55  VAL A CG2 1 
ATOM   427  N  N   . GLY A 1 56  ? 83.201  126.072 97.428  1.00 78.15  ? 56  GLY A N   1 
ATOM   428  C  CA  . GLY A 1 56  ? 83.977  127.283 97.338  1.00 78.15  ? 56  GLY A CA  1 
ATOM   429  C  C   . GLY A 1 56  ? 85.004  127.373 98.437  1.00 78.15  ? 56  GLY A C   1 
ATOM   430  O  O   . GLY A 1 56  ? 85.159  126.478 99.272  1.00 78.15  ? 56  GLY A O   1 
ATOM   431  N  N   . PRO A 1 57  ? 85.744  128.482 98.447  1.00 77.24  ? 57  PRO A N   1 
ATOM   432  C  CA  . PRO A 1 57  ? 86.812  128.626 99.443  1.00 77.24  ? 57  PRO A CA  1 
ATOM   433  C  C   . PRO A 1 57  ? 86.316  128.887 100.852 1.00 77.24  ? 57  PRO A C   1 
ATOM   434  O  O   . PRO A 1 57  ? 87.070  128.671 101.805 1.00 77.24  ? 57  PRO A O   1 
ATOM   435  C  CB  . PRO A 1 57  ? 87.636  129.800 98.903  1.00 77.24  ? 57  PRO A CB  1 
ATOM   436  C  CG  . PRO A 1 57  ? 86.716  130.539 98.038  1.00 77.24  ? 57  PRO A CG  1 
ATOM   437  C  CD  . PRO A 1 57  ? 85.792  129.544 97.434  1.00 77.24  ? 57  PRO A CD  1 
ATOM   438  N  N   . ASP A 1 58  ? 85.076  129.320 101.029 1.00 76.56  ? 58  ASP A N   1 
ATOM   439  C  CA  . ASP A 1 58  ? 84.583  129.665 102.354 1.00 76.56  ? 58  ASP A CA  1 
ATOM   440  C  C   . ASP A 1 58  ? 83.675  128.605 102.957 1.00 76.56  ? 58  ASP A C   1 
ATOM   441  O  O   . ASP A 1 58  ? 83.171  128.803 104.064 1.00 76.56  ? 58  ASP A O   1 
ATOM   442  C  CB  . ASP A 1 58  ? 83.842  130.996 102.297 1.00 76.56  ? 58  ASP A CB  1 
ATOM   443  C  CG  . ASP A 1 58  ? 82.608  130.928 101.441 1.00 76.56  ? 58  ASP A CG  1 
ATOM   444  O  OD1 . ASP A 1 58  ? 81.498  131.047 101.994 1.00 76.56  ? 58  ASP A OD1 1 
ATOM   445  O  OD2 . ASP A 1 58  ? 82.745  130.748 100.214 1.00 76.56  ? 58  ASP A OD2 1 
ATOM   446  N  N   . VAL A 1 59  ? 83.449  127.499 102.262 1.00 74.53  ? 59  VAL A N   1 
ATOM   447  C  CA  . VAL A 1 59  ? 82.560  126.434 102.726 1.00 74.53  ? 59  VAL A CA  1 
ATOM   448  C  C   . VAL A 1 59  ? 83.199  125.481 103.744 1.00 74.53  ? 59  VAL A C   1 
ATOM   449  O  O   . VAL A 1 59  ? 82.547  125.213 104.763 1.00 74.53  ? 59  VAL A O   1 
ATOM   450  C  CB  . VAL A 1 59  ? 81.971  125.676 101.522 1.00 74.53  ? 59  VAL A CB  1 
ATOM   451  C  CG1 . VAL A 1 59  ? 81.045  124.569 101.965 1.00 74.53  ? 59  VAL A CG1 1 
ATOM   452  C  CG2 . VAL A 1 59  ? 81.240  126.640 100.620 1.00 74.53  ? 59  VAL A CG2 1 
ATOM   453  N  N   . PRO A 1 60  ? 84.418  124.936 103.571 1.00 71.36  ? 60  PRO A N   1 
ATOM   454  C  CA  . PRO A 1 60  ? 84.903  123.965 104.559 1.00 71.36  ? 60  PRO A CA  1 
ATOM   455  C  C   . PRO A 1 60  ? 85.271  124.572 105.904 1.00 71.36  ? 60  PRO A C   1 
ATOM   456  O  O   . PRO A 1 60  ? 85.462  125.779 106.043 1.00 71.36  ? 60  PRO A O   1 
ATOM   457  C  CB  . PRO A 1 60  ? 86.139  123.368 103.882 1.00 71.36  ? 60  PRO A CB  1 
ATOM   458  C  CG  . PRO A 1 60  ? 85.942  123.613 102.477 1.00 71.36  ? 60  PRO A CG  1 
ATOM   459  C  CD  . PRO A 1 60  ? 85.367  124.958 102.441 1.00 71.36  ? 60  PRO A CD  1 
ATOM   460  N  N   . LEU A 1 61  ? 85.364  123.702 106.904 1.00 69.00  ? 61  LEU A N   1 
ATOM   461  C  CA  . LEU A 1 61  ? 85.690  124.078 108.269 1.00 69.00  ? 61  LEU A CA  1 
ATOM   462  C  C   . LEU A 1 61  ? 87.088  123.600 108.625 1.00 69.00  ? 61  LEU A C   1 
ATOM   463  O  O   . LEU A 1 61  ? 87.565  122.591 108.108 1.00 69.00  ? 61  LEU A O   1 
ATOM   464  C  CB  . LEU A 1 61  ? 84.688  123.494 109.259 1.00 69.00  ? 61  LEU A CB  1 
ATOM   465  C  CG  . LEU A 1 61  ? 83.211  123.612 108.914 1.00 69.00  ? 61  LEU A CG  1 
ATOM   466  C  CD1 . LEU A 1 61  ? 82.390  122.986 110.000 1.00 69.00  ? 61  LEU A CD1 1 
ATOM   467  C  CD2 . LEU A 1 61  ? 82.827  125.048 108.743 1.00 69.00  ? 61  LEU A CD2 1 
ATOM   468  N  N   . TRP A 1 62  ? 87.731  124.322 109.532 1.00 67.80  ? 62  TRP A N   1 
ATOM   469  C  CA  . TRP A 1 62  ? 89.141  124.145 109.834 1.00 67.80  ? 62  TRP A CA  1 
ATOM   470  C  C   . TRP A 1 62  ? 89.307  123.696 111.273 1.00 67.80  ? 62  TRP A C   1 
ATOM   471  O  O   . TRP A 1 62  ? 88.816  124.359 112.186 1.00 67.80  ? 62  TRP A O   1 
ATOM   472  C  CB  . TRP A 1 62  ? 89.901  125.450 109.615 1.00 67.80  ? 62  TRP A CB  1 
ATOM   473  C  CG  . TRP A 1 62  ? 90.010  125.847 108.198 1.00 67.80  ? 62  TRP A CG  1 
ATOM   474  C  CD1 . TRP A 1 62  ? 89.015  126.291 107.392 1.00 67.80  ? 62  TRP A CD1 1 
ATOM   475  C  CD2 . TRP A 1 62  ? 91.193  125.843 107.411 1.00 67.80  ? 62  TRP A CD2 1 
ATOM   476  N  NE1 . TRP A 1 62  ? 89.501  126.557 106.145 1.00 67.80  ? 62  TRP A NE1 1 
ATOM   477  C  CE2 . TRP A 1 62  ? 90.842  126.290 106.133 1.00 67.80  ? 62  TRP A CE2 1 
ATOM   478  C  CE3 . TRP A 1 62  ? 92.522  125.505 107.665 1.00 67.80  ? 62  TRP A CE3 1 
ATOM   479  C  CZ2 . TRP A 1 62  ? 91.765  126.400 105.111 1.00 67.80  ? 62  TRP A CZ2 1 
ATOM   480  C  CZ3 . TRP A 1 62  ? 93.432  125.612 106.649 1.00 67.80  ? 62  TRP A CZ3 1 
ATOM   481  C  CH2 . TRP A 1 62  ? 93.053  126.061 105.388 1.00 67.80  ? 62  TRP A CH2 1 
ATOM   482  N  N   . THR A 1 63  ? 90.009  122.592 111.477 1.00 69.32  ? 63  THR A N   1 
ATOM   483  C  CA  . THR A 1 63  ? 90.343  122.114 112.812 1.00 69.32  ? 63  THR A CA  1 
ATOM   484  C  C   . THR A 1 63  ? 91.806  122.424 113.076 1.00 69.32  ? 63  THR A C   1 
ATOM   485  O  O   . THR A 1 63  ? 92.693  121.735 112.570 1.00 69.32  ? 63  THR A O   1 
ATOM   486  C  CB  . THR A 1 63  ? 90.078  120.623 112.956 1.00 69.32  ? 63  THR A CB  1 
ATOM   487  O  OG1 . THR A 1 63  ? 88.759  120.325 112.494 1.00 69.32  ? 63  THR A OG1 1 
ATOM   488  C  CG2 . THR A 1 63  ? 90.203  120.216 114.396 1.00 69.32  ? 63  THR A CG2 1 
ATOM   489  N  N   . LEU A 1 64  ? 92.056  123.461 113.864 1.00 71.01  ? 64  LEU A N   1 
ATOM   490  C  CA  . LEU A 1 64  ? 93.403  123.911 114.171 1.00 71.01  ? 64  LEU A CA  1 
ATOM   491  C  C   . LEU A 1 64  ? 93.594  123.905 115.675 1.00 71.01  ? 64  LEU A C   1 
ATOM   492  O  O   . LEU A 1 64  ? 92.820  124.538 116.399 1.00 71.01  ? 64  LEU A O   1 
ATOM   493  C  CB  . LEU A 1 64  ? 93.654  125.303 113.608 1.00 71.01  ? 64  LEU A CB  1 
ATOM   494  C  CG  . LEU A 1 64  ? 93.608  125.340 112.090 1.00 71.01  ? 64  LEU A CG  1 
ATOM   495  C  CD1 . LEU A 1 64  ? 93.471  126.741 111.610 1.00 71.01  ? 64  LEU A CD1 1 
ATOM   496  C  CD2 . LEU A 1 64  ? 94.850  124.712 111.535 1.00 71.01  ? 64  LEU A CD2 1 
ATOM   497  N  N   . GLN A 1 65  ? 94.619  123.175 116.123 1.00 73.42  ? 65  GLN A N   1 
ATOM   498  C  CA  . GLN A 1 65  ? 94.985  123.025 117.533 1.00 73.42  ? 65  GLN A CA  1 
ATOM   499  C  C   . GLN A 1 65  ? 93.834  122.478 118.372 1.00 73.42  ? 65  GLN A C   1 
ATOM   500  O  O   . GLN A 1 65  ? 93.571  122.949 119.477 1.00 73.42  ? 65  GLN A O   1 
ATOM   501  C  CB  . GLN A 1 65  ? 95.512  124.335 118.113 1.00 73.42  ? 65  GLN A CB  1 
ATOM   502  C  CG  . GLN A 1 65  ? 96.782  124.808 117.465 1.00 73.42  ? 65  GLN A CG  1 
ATOM   503  C  CD  . GLN A 1 65  ? 97.140  126.204 117.876 1.00 73.42  ? 65  GLN A CD  1 
ATOM   504  O  OE1 . GLN A 1 65  ? 96.273  127.055 118.020 1.00 73.42  ? 65  GLN A OE1 1 
ATOM   505  N  NE2 . GLN A 1 65  ? 98.422  126.452 118.075 1.00 73.42  ? 65  GLN A NE2 1 
ATOM   506  N  N   . GLY A 1 66  ? 93.138  121.480 117.839 1.00 75.80  ? 66  GLY A N   1 
ATOM   507  C  CA  . GLY A 1 66  ? 92.128  120.767 118.589 1.00 75.80  ? 66  GLY A CA  1 
ATOM   508  C  C   . GLY A 1 66  ? 90.767  121.416 118.652 1.00 75.80  ? 66  GLY A C   1 
ATOM   509  O  O   . GLY A 1 66  ? 89.947  121.005 119.476 1.00 75.80  ? 66  GLY A O   1 
ATOM   510  N  N   . GLN A 1 67  ? 90.495  122.409 117.818 1.00 76.19  ? 67  GLN A N   1 
ATOM   511  C  CA  . GLN A 1 67  ? 89.238  123.136 117.853 1.00 76.19  ? 67  GLN A CA  1 
ATOM   512  C  C   . GLN A 1 67  ? 88.815  123.463 116.432 1.00 76.19  ? 67  GLN A C   1 
ATOM   513  O  O   . GLN A 1 67  ? 89.637  123.890 115.622 1.00 76.19  ? 67  GLN A O   1 
ATOM   514  C  CB  . GLN A 1 67  ? 89.386  124.411 118.673 1.00 76.19  ? 67  GLN A CB  1 
ATOM   515  C  CG  . GLN A 1 67  ? 88.112  125.179 118.877 1.00 76.19  ? 67  GLN A CG  1 
ATOM   516  C  CD  . GLN A 1 67  ? 87.125  124.433 119.716 1.00 76.19  ? 67  GLN A CD  1 
ATOM   517  O  OE1 . GLN A 1 67  ? 86.120  123.930 119.215 1.00 76.19  ? 67  GLN A OE1 1 
ATOM   518  N  NE2 . GLN A 1 67  ? 87.402  124.344 121.008 1.00 76.19  ? 67  GLN A NE2 1 
ATOM   519  N  N   . GLN A 1 68  ? 87.537  123.271 116.130 1.00 72.22  ? 68  GLN A N   1 
ATOM   520  C  CA  . GLN A 1 68  ? 87.032  123.456 114.778 1.00 72.22  ? 68  GLN A CA  1 
ATOM   521  C  C   . GLN A 1 68  ? 86.431  124.842 114.612 1.00 72.22  ? 68  GLN A C   1 
ATOM   522  O  O   . GLN A 1 68  ? 85.709  125.325 115.485 1.00 72.22  ? 68  GLN A O   1 
ATOM   523  C  CB  . GLN A 1 68  ? 85.989  122.401 114.428 1.00 72.22  ? 68  GLN A CB  1 
ATOM   524  C  CG  . GLN A 1 68  ? 85.696  122.334 112.955 1.00 72.22  ? 68  GLN A CG  1 
ATOM   525  C  CD  . GLN A 1 68  ? 84.683  121.286 112.613 1.00 72.22  ? 68  GLN A CD  1 
ATOM   526  O  OE1 . GLN A 1 68  ? 83.537  121.356 113.042 1.00 72.22  ? 68  GLN A OE1 1 
ATOM   527  N  NE2 . GLN A 1 68  ? 85.093  120.307 111.827 1.00 72.22  ? 68  GLN A NE2 1 
ATOM   528  N  N   . TYR A 1 69  ? 86.727  125.472 113.478 1.00 72.58  ? 69  TYR A N   1 
ATOM   529  C  CA  . TYR A 1 69  ? 86.269  126.819 113.190 1.00 72.58  ? 69  TYR A CA  1 
ATOM   530  C  C   . TYR A 1 69  ? 85.737  126.903 111.771 1.00 72.58  ? 69  TYR A C   1 
ATOM   531  O  O   . TYR A 1 69  ? 86.124  126.132 110.894 1.00 72.58  ? 69  TYR A O   1 
ATOM   532  C  CB  . TYR A 1 69  ? 87.386  127.847 113.337 1.00 72.58  ? 69  TYR A CB  1 
ATOM   533  C  CG  . TYR A 1 69  ? 88.089  127.848 114.660 1.00 72.58  ? 69  TYR A CG  1 
ATOM   534  C  CD1 . TYR A 1 69  ? 87.638  128.640 115.697 1.00 72.58  ? 69  TYR A CD1 1 
ATOM   535  C  CD2 . TYR A 1 69  ? 89.218  127.077 114.865 1.00 72.58  ? 69  TYR A CD2 1 
ATOM   536  C  CE1 . TYR A 1 69  ? 88.278  128.651 116.901 1.00 72.58  ? 69  TYR A CE1 1 
ATOM   537  C  CE2 . TYR A 1 69  ? 89.862  127.082 116.066 1.00 72.58  ? 69  TYR A CE2 1 
ATOM   538  C  CZ  . TYR A 1 69  ? 89.391  127.874 117.077 1.00 72.58  ? 69  TYR A CZ  1 
ATOM   539  O  OH  . TYR A 1 69  ? 90.036  127.878 118.283 1.00 72.58  ? 69  TYR A OH  1 
ATOM   540  N  N   . THR A 1 70  ? 84.847  127.862 111.554 1.00 73.83  ? 70  THR A N   1 
ATOM   541  C  CA  . THR A 1 70  ? 84.521  128.281 110.206 1.00 73.83  ? 70  THR A CA  1 
ATOM   542  C  C   . THR A 1 70  ? 85.535  129.318 109.743 1.00 73.83  ? 70  THR A C   1 
ATOM   543  O  O   . THR A 1 70  ? 86.386  129.768 110.507 1.00 73.83  ? 70  THR A O   1 
ATOM   544  C  CB  . THR A 1 70  ? 83.112  128.855 110.141 1.00 73.83  ? 70  THR A CB  1 
ATOM   545  O  OG1 . THR A 1 70  ? 83.125  130.189 110.647 1.00 73.83  ? 70  THR A OG1 1 
ATOM   546  C  CG2 . THR A 1 70  ? 82.175  128.035 110.975 1.00 73.83  ? 70  THR A CG2 1 
ATOM   547  N  N   . LEU A 1 71  ? 85.446  129.699 108.470 1.00 74.32  ? 71  LEU A N   1 
ATOM   548  C  CA  . LEU A 1 71  ? 86.398  130.666 107.938 1.00 74.32  ? 71  LEU A CA  1 
ATOM   549  C  C   . LEU A 1 71  ? 86.133  132.058 108.488 1.00 74.32  ? 71  LEU A C   1 
ATOM   550  O  O   . LEU A 1 71  ? 87.070  132.830 108.712 1.00 74.32  ? 71  LEU A O   1 
ATOM   551  C  CB  . LEU A 1 71  ? 86.351  130.675 106.415 1.00 74.32  ? 71  LEU A CB  1 
ATOM   552  C  CG  . LEU A 1 71  ? 87.436  131.509 105.738 1.00 74.32  ? 71  LEU A CG  1 
ATOM   553  C  CD1 . LEU A 1 71  ? 88.796  130.944 106.044 1.00 74.32  ? 71  LEU A CD1 1 
ATOM   554  C  CD2 . LEU A 1 71  ? 87.214  131.588 104.255 1.00 74.32  ? 71  LEU A CD2 1 
ATOM   555  N  N   . ALA A 1 72  ? 84.867  132.389 108.737 1.00 75.30  ? 72  ALA A N   1 
ATOM   556  C  CA  . ALA A 1 72  ? 84.547  133.689 109.313 1.00 75.30  ? 72  ALA A CA  1 
ATOM   557  C  C   . ALA A 1 72  ? 84.980  133.769 110.769 1.00 75.30  ? 72  ALA A C   1 
ATOM   558  O  O   . ALA A 1 72  ? 85.345  134.841 111.254 1.00 75.30  ? 72  ALA A O   1 
ATOM   559  C  CB  . ALA A 1 72  ? 83.055  133.968 109.183 1.00 75.30  ? 72  ALA A CB  1 
ATOM   560  N  N   . GLU A 1 73  ? 84.951  132.643 111.480 1.00 76.84  ? 73  GLU A N   1 
ATOM   561  C  CA  . GLU A 1 73  ? 85.448  132.624 112.850 1.00 76.84  ? 73  GLU A CA  1 
ATOM   562  C  C   . GLU A 1 73  ? 86.961  132.727 112.883 1.00 76.84  ? 73  GLU A C   1 
ATOM   563  O  O   . GLU A 1 73  ? 87.532  133.244 113.847 1.00 76.84  ? 73  GLU A O   1 
ATOM   564  C  CB  . GLU A 1 73  ? 85.004  131.350 113.556 1.00 76.84  ? 73  GLU A CB  1 
ATOM   565  C  CG  . GLU A 1 73  ? 83.561  131.328 113.964 1.00 76.84  ? 73  GLU A CG  1 
ATOM   566  C  CD  . GLU A 1 73  ? 83.163  129.996 114.546 1.00 76.84  ? 73  GLU A CD  1 
ATOM   567  O  OE1 . GLU A 1 73  ? 83.908  129.016 114.350 1.00 76.84  ? 73  GLU A OE1 1 
ATOM   568  O  OE2 . GLU A 1 73  ? 82.105  129.927 115.202 1.00 76.84  ? 73  GLU A OE2 1 
ATOM   569  N  N   . LEU A 1 74  ? 87.628  132.213 111.851 1.00 74.23  ? 74  LEU A N   1 
ATOM   570  C  CA  . LEU A 1 74  ? 89.076  132.335 111.771 1.00 74.23  ? 74  LEU A CA  1 
ATOM   571  C  C   . LEU A 1 74  ? 89.489  133.770 111.506 1.00 74.23  ? 74  LEU A C   1 
ATOM   572  O  O   . LEU A 1 74  ? 90.518  134.226 112.009 1.00 74.23  ? 74  LEU A O   1 
ATOM   573  C  CB  . LEU A 1 74  ? 89.621  131.426 110.675 1.00 74.23  ? 74  LEU A CB  1 
ATOM   574  C  CG  . LEU A 1 74  ? 89.702  129.934 110.955 1.00 74.23  ? 74  LEU A CG  1 
ATOM   575  C  CD1 . LEU A 1 74  ? 90.431  129.251 109.835 1.00 74.23  ? 74  LEU A CD1 1 
ATOM   576  C  CD2 . LEU A 1 74  ? 90.397  129.689 112.256 1.00 74.23  ? 74  LEU A CD2 1 
ATOM   577  N  N   . TRP A 1 75  ? 88.690  134.499 110.728 1.00 75.64  ? 75  TRP A N   1 
ATOM   578  C  CA  . TRP A 1 75  ? 89.050  135.859 110.345 1.00 75.64  ? 75  TRP A CA  1 
ATOM   579  C  C   . TRP A 1 75  ? 88.966  136.813 111.526 1.00 75.64  ? 75  TRP A C   1 
ATOM   580  O  O   . TRP A 1 75  ? 89.712  137.794 111.592 1.00 75.64  ? 75  TRP A O   1 
ATOM   581  C  CB  . TRP A 1 75  ? 88.145  136.334 109.218 1.00 75.64  ? 75  TRP A CB  1 
ATOM   582  C  CG  . TRP A 1 75  ? 88.567  135.850 107.898 1.00 75.64  ? 75  TRP A CG  1 
ATOM   583  C  CD1 . TRP A 1 75  ? 89.761  135.305 107.578 1.00 75.64  ? 75  TRP A CD1 1 
ATOM   584  C  CD2 . TRP A 1 75  ? 87.796  135.864 106.700 1.00 75.64  ? 75  TRP A CD2 1 
ATOM   585  N  NE1 . TRP A 1 75  ? 89.791  134.975 106.251 1.00 75.64  ? 75  TRP A NE1 1 
ATOM   586  C  CE2 . TRP A 1 75  ? 88.591  135.311 105.689 1.00 75.64  ? 75  TRP A CE2 1 
ATOM   587  C  CE3 . TRP A 1 75  ? 86.508  136.289 106.386 1.00 75.64  ? 75  TRP A CE3 1 
ATOM   588  C  CZ2 . TRP A 1 75  ? 88.143  135.173 104.387 1.00 75.64  ? 75  TRP A CZ2 1 
ATOM   589  C  CZ3 . TRP A 1 75  ? 86.068  136.156 105.098 1.00 75.64  ? 75  TRP A CZ3 1 
ATOM   590  C  CH2 . TRP A 1 75  ? 86.879  135.602 104.112 1.00 75.64  ? 75  TRP A CH2 1 
ATOM   591  N  N   . ASP A 1 76  ? 88.072  136.544 112.465 1.00 80.79  ? 76  ASP A N   1 
ATOM   592  C  CA  . ASP A 1 76  ? 87.938  137.367 113.655 1.00 80.79  ? 76  ASP A CA  1 
ATOM   593  C  C   . ASP A 1 76  ? 88.687  136.805 114.851 1.00 80.79  ? 76  ASP A C   1 
ATOM   594  O  O   . ASP A 1 76  ? 88.716  137.449 115.902 1.00 80.79  ? 76  ASP A O   1 
ATOM   595  C  CB  . ASP A 1 76  ? 86.465  137.532 114.013 1.00 80.79  ? 76  ASP A CB  1 
ATOM   596  C  CG  . ASP A 1 76  ? 85.648  138.058 112.863 1.00 80.79  ? 76  ASP A CG  1 
ATOM   597  O  OD1 . ASP A 1 76  ? 86.236  138.366 111.809 1.00 80.79  ? 76  ASP A OD1 1 
ATOM   598  O  OD2 . ASP A 1 76  ? 84.416  138.170 113.010 1.00 80.79  ? 76  ASP A OD2 1 
ATOM   599  N  N   . GLY A 1 77  ? 89.291  135.632 114.721 1.00 82.25  ? 77  GLY A N   1 
ATOM   600  C  CA  . GLY A 1 77  ? 89.899  134.989 115.862 1.00 82.25  ? 77  GLY A CA  1 
ATOM   601  C  C   . GLY A 1 77  ? 91.250  135.573 116.219 1.00 82.25  ? 77  GLY A C   1 
ATOM   602  O  O   . GLY A 1 77  ? 91.869  136.308 115.456 1.00 82.25  ? 77  GLY A O   1 
ATOM   603  N  N   . ASP A 1 78  ? 91.707  135.224 117.418 1.00 85.21  ? 78  ASP A N   1 
ATOM   604  C  CA  . ASP A 1 78  ? 93.010  135.626 117.922 1.00 85.21  ? 78  ASP A CA  1 
ATOM   605  C  C   . ASP A 1 78  ? 93.662  134.444 118.612 1.00 85.21  ? 78  ASP A C   1 
ATOM   606  O  O   . ASP A 1 78  ? 92.989  133.671 119.296 1.00 85.21  ? 78  ASP A O   1 
ATOM   607  C  CB  . ASP A 1 78  ? 92.889  136.794 118.897 1.00 85.21  ? 78  ASP A CB  1 
ATOM   608  C  CG  . ASP A 1 78  ? 92.622  138.103 118.201 1.00 85.21  ? 78  ASP A CG  1 
ATOM   609  O  OD1 . ASP A 1 78  ? 93.161  138.304 117.096 1.00 85.21  ? 78  ASP A OD1 1 
ATOM   610  O  OD2 . ASP A 1 78  ? 91.859  138.926 118.745 1.00 85.21  ? 78  ASP A OD2 1 
ATOM   611  N  N   . GLY A 1 79  ? 94.967  134.301 118.424 1.00 79.72  ? 79  GLY A N   1 
ATOM   612  C  CA  . GLY A 1 79  ? 95.722  133.280 119.109 1.00 79.72  ? 79  GLY A CA  1 
ATOM   613  C  C   . GLY A 1 79  ? 95.723  131.915 118.465 1.00 79.72  ? 79  GLY A C   1 
ATOM   614  O  O   . GLY A 1 79  ? 96.591  131.102 118.795 1.00 79.72  ? 79  GLY A O   1 
ATOM   615  N  N   . VAL A 1 80  ? 94.796  131.630 117.569 1.00 73.95  ? 80  VAL A N   1 
ATOM   616  C  CA  . VAL A 1 80  ? 94.747  130.341 116.893 1.00 73.95  ? 80  VAL A CA  1 
ATOM   617  C  C   . VAL A 1 80  ? 95.778  130.344 115.781 1.00 73.95  ? 80  VAL A C   1 
ATOM   618  O  O   . VAL A 1 80  ? 95.900  131.319 115.035 1.00 73.95  ? 80  VAL A O   1 
ATOM   619  C  CB  . VAL A 1 80  ? 93.341  130.060 116.343 1.00 73.95  ? 80  VAL A CB  1 
ATOM   620  C  CG1 . VAL A 1 80  ? 93.210  128.608 115.952 1.00 73.95  ? 80  VAL A CG1 1 
ATOM   621  C  CG2 . VAL A 1 80  ? 92.302  130.430 117.365 1.00 73.95  ? 80  VAL A CG2 1 
ATOM   622  N  N   . ARG A 1 81  ? 96.529  129.256 115.670 1.00 72.41  ? 81  ARG A N   1 
ATOM   623  C  CA  . ARG A 1 81  ? 97.592  129.145 114.691 1.00 72.41  ? 81  ARG A CA  1 
ATOM   624  C  C   . ARG A 1 81  ? 97.462  127.848 113.913 1.00 72.41  ? 81  ARG A C   1 
ATOM   625  O  O   . ARG A 1 81  ? 96.870  126.875 114.376 1.00 72.41  ? 81  ARG A O   1 
ATOM   626  C  CB  . ARG A 1 81  ? 98.967  129.203 115.352 1.00 72.41  ? 81  ARG A CB  1 
ATOM   627  C  CG  . ARG A 1 81  ? 99.281  130.526 115.996 1.00 72.41  ? 81  ARG A CG  1 
ATOM   628  C  CD  . ARG A 1 81  ? 100.732 130.637 116.379 1.00 72.41  ? 81  ARG A CD  1 
ATOM   629  N  NE  . ARG A 1 81  ? 101.606 130.661 115.217 1.00 72.41  ? 81  ARG A NE  1 
ATOM   630  C  CZ  . ARG A 1 81  ? 102.375 129.644 114.860 1.00 72.41  ? 81  ARG A CZ  1 
ATOM   631  N  NH1 . ARG A 1 81  ? 102.360 128.527 115.569 1.00 72.41  ? 81  ARG A NH1 1 
ATOM   632  N  NH2 . ARG A 1 81  ? 103.140 129.729 113.794 1.00 72.41  ? 81  ARG A NH2 1 
ATOM   633  N  N   . TRP A 1 82  ? 98.014  127.862 112.708 1.00 70.18  ? 82  TRP A N   1 
ATOM   634  C  CA  . TRP A 1 82  ? 98.297  126.659 111.940 1.00 70.18  ? 82  TRP A CA  1 
ATOM   635  C  C   . TRP A 1 82  ? 99.790  126.419 112.086 1.00 70.18  ? 82  TRP A C   1 
ATOM   636  O  O   . TRP A 1 82  ? 100.586 127.054 111.391 1.00 70.18  ? 82  TRP A O   1 
ATOM   637  C  CB  . TRP A 1 82  ? 97.896  126.836 110.473 1.00 70.18  ? 82  TRP A CB  1 
ATOM   638  C  CG  . TRP A 1 82  ? 98.058  125.633 109.568 1.00 70.18  ? 82  TRP A CG  1 
ATOM   639  C  CD1 . TRP A 1 82  ? 98.541  124.404 109.895 1.00 70.18  ? 82  TRP A CD1 1 
ATOM   640  C  CD2 . TRP A 1 82  ? 97.728  125.569 108.180 1.00 70.18  ? 82  TRP A CD2 1 
ATOM   641  N  NE1 . TRP A 1 82  ? 98.540  123.587 108.804 1.00 70.18  ? 82  TRP A NE1 1 
ATOM   642  C  CE2 . TRP A 1 82  ? 98.042  124.279 107.736 1.00 70.18  ? 82  TRP A CE2 1 
ATOM   643  C  CE3 . TRP A 1 82  ? 97.194  126.480 107.271 1.00 70.18  ? 82  TRP A CE3 1 
ATOM   644  C  CZ2 . TRP A 1 82  ? 97.840  123.876 106.426 1.00 70.18  ? 82  TRP A CZ2 1 
ATOM   645  C  CZ3 . TRP A 1 82  ? 96.999  126.080 105.976 1.00 70.18  ? 82  TRP A CZ3 1 
ATOM   646  C  CH2 . TRP A 1 82  ? 97.319  124.791 105.564 1.00 70.18  ? 82  TRP A CH2 1 
ATOM   647  N  N   . PRO A 1 83  ? 100.214 125.536 112.983 1.00 71.69  ? 83  PRO A N   1 
ATOM   648  C  CA  . PRO A 1 83  ? 101.646 125.296 113.160 1.00 71.69  ? 83  PRO A CA  1 
ATOM   649  C  C   . PRO A 1 83  ? 102.223 124.509 112.001 1.00 71.69  ? 83  PRO A C   1 
ATOM   650  O  O   . PRO A 1 83  ? 101.519 123.773 111.312 1.00 71.69  ? 83  PRO A O   1 
ATOM   651  C  CB  . PRO A 1 83  ? 101.709 124.488 114.458 1.00 71.69  ? 83  PRO A CB  1 
ATOM   652  C  CG  . PRO A 1 83  ? 100.385 124.668 115.091 1.00 71.69  ? 83  PRO A CG  1 
ATOM   653  C  CD  . PRO A 1 83  ? 99.424  124.813 113.983 1.00 71.69  ? 83  PRO A CD  1 
ATOM   654  N  N   . LEU A 1 84  ? 103.528 124.677 111.790 1.00 72.97  ? 84  LEU A N   1 
ATOM   655  C  CA  . LEU A 1 84  ? 104.190 123.994 110.685 1.00 72.97  ? 84  LEU A CA  1 
ATOM   656  C  C   . LEU A 1 84  ? 104.296 122.500 110.947 1.00 72.97  ? 84  LEU A C   1 
ATOM   657  O  O   . LEU A 1 84  ? 104.256 121.694 110.014 1.00 72.97  ? 84  LEU A O   1 
ATOM   658  C  CB  . LEU A 1 84  ? 105.571 124.596 110.454 1.00 72.97  ? 84  LEU A CB  1 
ATOM   659  C  CG  . LEU A 1 84  ? 106.291 124.177 109.177 1.00 72.97  ? 84  LEU A CG  1 
ATOM   660  C  CD1 . LEU A 1 84  ? 105.680 124.861 107.985 1.00 72.97  ? 84  LEU A CD1 1 
ATOM   661  C  CD2 . LEU A 1 84  ? 107.761 124.489 109.275 1.00 72.97  ? 84  LEU A CD2 1 
ATOM   662  N  N   . GLU A 1 85  ? 104.406 122.112 112.213 1.00 74.47  ? 85  GLU A N   1 
ATOM   663  C  CA  . GLU A 1 85  ? 104.497 120.702 112.557 1.00 74.47  ? 85  GLU A CA  1 
ATOM   664  C  C   . GLU A 1 85  ? 103.151 119.999 112.493 1.00 74.47  ? 85  GLU A C   1 
ATOM   665  O  O   . GLU A 1 85  ? 103.113 118.767 112.497 1.00 74.47  ? 85  GLU A O   1 
ATOM   666  C  CB  . GLU A 1 85  ? 105.103 120.547 113.949 1.00 74.47  ? 85  GLU A CB  1 
ATOM   667  C  CG  . GLU A 1 85  ? 104.153 120.845 115.084 1.00 74.47  ? 85  GLU A CG  1 
ATOM   668  C  CD  . GLU A 1 85  ? 104.367 122.215 115.685 1.00 74.47  ? 85  GLU A CD  1 
ATOM   669  O  OE1 . GLU A 1 85  ? 105.047 123.046 115.053 1.00 74.47  ? 85  GLU A OE1 1 
ATOM   670  O  OE2 . GLU A 1 85  ? 103.854 122.464 116.794 1.00 74.47  ? 85  GLU A OE2 1 
ATOM   671  N  N   . ASP A 1 86  ? 102.056 120.744 112.429 1.00 74.19  ? 86  ASP A N   1 
ATOM   672  C  CA  . ASP A 1 86  ? 100.719 120.178 112.399 1.00 74.19  ? 86  ASP A CA  1 
ATOM   673  C  C   . ASP A 1 86  ? 100.135 120.265 111.000 1.00 74.19  ? 86  ASP A C   1 
ATOM   674  O  O   . ASP A 1 86  ? 100.409 121.201 110.249 1.00 74.19  ? 86  ASP A O   1 
ATOM   675  C  CB  . ASP A 1 86  ? 99.797  120.907 113.372 1.00 74.19  ? 86  ASP A CB  1 
ATOM   676  C  CG  . ASP A 1 86  ? 100.019 120.494 114.802 1.00 74.19  ? 86  ASP A CG  1 
ATOM   677  O  OD1 . ASP A 1 86  ? 100.835 119.585 115.041 1.00 74.19  ? 86  ASP A OD1 1 
ATOM   678  O  OD2 . ASP A 1 86  ? 99.372  121.076 115.693 1.00 74.19  ? 86  ASP A OD2 1 
ATOM   679  N  N   . ALA A 1 87  ? 99.323  119.277 110.657 1.00 69.35  ? 87  ALA A N   1 
ATOM   680  C  CA  . ALA A 1 87  ? 98.527  119.314 109.442 1.00 69.35  ? 87  ALA A CA  1 
ATOM   681  C  C   . ALA A 1 87  ? 97.137  119.814 109.796 1.00 69.35  ? 87  ALA A C   1 
ATOM   682  O  O   . ALA A 1 87  ? 96.566  119.401 110.807 1.00 69.35  ? 87  ALA A O   1 
ATOM   683  C  CB  . ALA A 1 87  ? 98.450  117.938 108.788 1.00 69.35  ? 87  ALA A CB  1 
ATOM   684  N  N   . ALA A 1 88  ? 96.607  120.717 108.981 1.00 67.70  ? 88  ALA A N   1 
ATOM   685  C  CA  . ALA A 1 88  ? 95.263  121.219 109.206 1.00 67.70  ? 88  ALA A CA  1 
ATOM   686  C  C   . ALA A 1 88  ? 94.241  120.195 108.754 1.00 67.70  ? 88  ALA A C   1 
ATOM   687  O  O   . ALA A 1 88  ? 94.378  119.598 107.690 1.00 67.70  ? 88  ALA A O   1 
ATOM   688  C  CB  . ALA A 1 88  ? 95.052  122.523 108.452 1.00 67.70  ? 88  ALA A CB  1 
ATOM   689  N  N   . ILE A 1 89  ? 93.207  119.998 109.558 1.00 66.61  ? 89  ILE A N   1 
ATOM   690  C  CA  . ILE A 1 89  ? 92.142  119.057 109.242 1.00 66.61  ? 89  ILE A CA  1 
ATOM   691  C  C   . ILE A 1 89  ? 90.997  119.838 108.618 1.00 66.61  ? 89  ILE A C   1 
ATOM   692  O  O   . ILE A 1 89  ? 90.410  120.715 109.257 1.00 66.61  ? 89  ILE A O   1 
ATOM   693  C  CB  . ILE A 1 89  ? 91.689  118.286 110.484 1.00 66.61  ? 89  ILE A CB  1 
ATOM   694  C  CG1 . ILE A 1 89  ? 92.901  117.714 111.204 1.00 66.61  ? 89  ILE A CG1 1 
ATOM   695  C  CG2 . ILE A 1 89  ? 90.756  117.176 110.098 1.00 66.61  ? 89  ILE A CG2 1 
ATOM   696  C  CD1 . ILE A 1 89  ? 92.619  117.274 112.594 1.00 66.61  ? 89  ILE A CD1 1 
ATOM   697  N  N   . ILE A 1 90  ? 90.678  119.521 107.375 1.00 67.76  ? 90  ILE A N   1 
ATOM   698  C  CA  . ILE A 1 90  ? 89.699  120.260 106.590 1.00 67.76  ? 90  ILE A CA  1 
ATOM   699  C  C   . ILE A 1 90  ? 88.426  119.448 106.497 1.00 67.76  ? 90  ILE A C   1 
ATOM   700  O  O   . ILE A 1 90  ? 88.402  118.414 105.834 1.00 67.76  ? 90  ILE A O   1 
ATOM   701  C  CB  . ILE A 1 90  ? 90.239  120.556 105.184 1.00 67.76  ? 90  ILE A CB  1 
ATOM   702  C  CG1 . ILE A 1 90  ? 91.581  121.268 105.263 1.00 67.76  ? 90  ILE A CG1 1 
ATOM   703  C  CG2 . ILE A 1 90  ? 89.239  121.356 104.399 1.00 67.76  ? 90  ILE A CG2 1 
ATOM   704  C  CD1 . ILE A 1 90  ? 91.508  122.568 105.928 1.00 67.76  ? 90  ILE A CD1 1 
ATOM   705  N  N   . PHE A 1 91  ? 87.357  119.920 107.123 1.00 69.64  ? 91  PHE A N   1 
ATOM   706  C  CA  . PHE A 1 91  ? 86.073  119.243 107.063 1.00 69.64  ? 91  PHE A CA  1 
ATOM   707  C  C   . PHE A 1 91  ? 85.234  119.856 105.959 1.00 69.64  ? 91  PHE A C   1 
ATOM   708  O  O   . PHE A 1 91  ? 84.919  121.043 106.011 1.00 69.64  ? 91  PHE A O   1 
ATOM   709  C  CB  . PHE A 1 91  ? 85.323  119.338 108.387 1.00 69.64  ? 91  PHE A CB  1 
ATOM   710  C  CG  . PHE A 1 91  ? 83.917  118.843 108.310 1.00 69.64  ? 91  PHE A CG  1 
ATOM   711  C  CD1 . PHE A 1 91  ? 83.661  117.495 108.216 1.00 69.64  ? 91  PHE A CD1 1 
ATOM   712  C  CD2 . PHE A 1 91  ? 82.852  119.723 108.324 1.00 69.64  ? 91  PHE A CD2 1 
ATOM   713  C  CE1 . PHE A 1 91  ? 82.374  117.033 108.138 1.00 69.64  ? 91  PHE A CE1 1 
ATOM   714  C  CE2 . PHE A 1 91  ? 81.564  119.263 108.240 1.00 69.64  ? 91  PHE A CE2 1 
ATOM   715  C  CZ  . PHE A 1 91  ? 81.326  117.918 108.149 1.00 69.64  ? 91  PHE A CZ  1 
ATOM   716  N  N   . VAL A 1 92  ? 84.845  119.046 104.987 1.00 70.08  ? 92  VAL A N   1 
ATOM   717  C  CA  . VAL A 1 92  ? 83.994  119.482 103.889 1.00 70.08  ? 92  VAL A CA  1 
ATOM   718  C  C   . VAL A 1 92  ? 82.598  118.924 104.131 1.00 70.08  ? 92  VAL A C   1 
ATOM   719  O  O   . VAL A 1 92  ? 82.436  117.706 104.233 1.00 70.08  ? 92  VAL A O   1 
ATOM   720  C  CB  . VAL A 1 92  ? 84.534  119.025 102.526 1.00 70.08  ? 92  VAL A CB  1 
ATOM   721  C  CG1 . VAL A 1 92  ? 83.629  119.500 101.424 1.00 70.08  ? 92  VAL A CG1 1 
ATOM   722  C  CG2 . VAL A 1 92  ? 85.927  119.546 102.319 1.00 70.08  ? 92  VAL A CG2 1 
ATOM   723  N  N   . PRO A 1 93  ? 81.569  119.765 104.238 1.00 72.19  ? 93  PRO A N   1 
ATOM   724  C  CA  . PRO A 1 93  ? 80.214  119.269 104.509 1.00 72.19  ? 93  PRO A CA  1 
ATOM   725  C  C   . PRO A 1 93  ? 79.621  118.596 103.281 1.00 72.19  ? 93  PRO A C   1 
ATOM   726  O  O   . PRO A 1 93  ? 79.497  119.207 102.220 1.00 72.19  ? 93  PRO A O   1 
ATOM   727  C  CB  . PRO A 1 93  ? 79.440  120.537 104.882 1.00 72.19  ? 93  PRO A CB  1 
ATOM   728  C  CG  . PRO A 1 93  ? 80.475  121.567 105.139 1.00 72.19  ? 93  PRO A CG  1 
ATOM   729  C  CD  . PRO A 1 93  ? 81.619  121.230 104.264 1.00 72.19  ? 93  PRO A CD  1 
ATOM   730  N  N   . LEU A 1 94  ? 79.258  117.340 103.433 1.00 75.97  ? 94  LEU A N   1 
ATOM   731  C  CA  . LEU A 1 94  ? 78.657  116.549 102.371 1.00 75.97  ? 94  LEU A CA  1 
ATOM   732  C  C   . LEU A 1 94  ? 77.820  115.452 103.006 1.00 75.97  ? 94  LEU A C   1 
ATOM   733  O  O   . LEU A 1 94  ? 78.375  114.445 103.457 1.00 75.97  ? 94  LEU A O   1 
ATOM   734  C  CB  . LEU A 1 94  ? 79.728  115.950 101.467 1.00 75.97  ? 94  LEU A CB  1 
ATOM   735  C  CG  . LEU A 1 94  ? 79.226  115.181 100.253 1.00 75.97  ? 94  LEU A CG  1 
ATOM   736  C  CD1 . LEU A 1 94  ? 78.662  116.134 99.235  1.00 75.97  ? 94  LEU A CD1 1 
ATOM   737  C  CD2 . LEU A 1 94  ? 80.345  114.377 99.654  1.00 75.97  ? 94  LEU A CD2 1 
ATOM   738  N  N   . PRO A 1 95  ? 76.501  115.614 103.080 1.00 79.29  ? 95  PRO A N   1 
ATOM   739  C  CA  . PRO A 1 95  ? 75.671  114.638 103.799 1.00 79.29  ? 95  PRO A CA  1 
ATOM   740  C  C   . PRO A 1 95  ? 75.610  113.303 103.073 1.00 79.29  ? 95  PRO A C   1 
ATOM   741  O  O   . PRO A 1 95  ? 75.178  113.217 101.924 1.00 79.29  ? 95  PRO A O   1 
ATOM   742  C  CB  . PRO A 1 95  ? 74.299  115.315 103.858 1.00 79.29  ? 95  PRO A CB  1 
ATOM   743  C  CG  . PRO A 1 95  ? 74.315  116.307 102.763 1.00 79.29  ? 95  PRO A CG  1 
ATOM   744  C  CD  . PRO A 1 95  ? 75.720  116.772 102.620 1.00 79.29  ? 95  PRO A CD  1 
ATOM   745  N  N   . GLY A 1 96  ? 76.055  112.257 103.762 1.00 79.69  ? 96  GLY A N   1 
ATOM   746  C  CA  . GLY A 1 96  ? 76.237  110.960 103.170 1.00 79.69  ? 96  GLY A CA  1 
ATOM   747  C  C   . GLY A 1 96  ? 77.679  110.575 102.933 1.00 79.69  ? 96  GLY A C   1 
ATOM   748  O  O   . GLY A 1 96  ? 77.986  109.382 102.891 1.00 79.69  ? 96  GLY A O   1 
ATOM   749  N  N   . GLY A 1 97  ? 78.568  111.545 102.781 1.00 76.60  ? 97  GLY A N   1 
ATOM   750  C  CA  . GLY A 1 97  ? 79.970  111.263 102.603 1.00 76.60  ? 97  GLY A CA  1 
ATOM   751  C  C   . GLY A 1 97  ? 80.309  110.808 101.198 1.00 76.60  ? 97  GLY A C   1 
ATOM   752  O  O   . GLY A 1 97  ? 79.492  110.818 100.282 1.00 76.60  ? 97  GLY A O   1 
ATOM   753  N  N   . LEU A 1 98  ? 81.547  110.407 101.047 1.00 74.05  ? 98  LEU A N   1 
ATOM   754  C  CA  . LEU A 1 98  ? 82.086  109.890 99.804  1.00 74.05  ? 98  LEU A CA  1 
ATOM   755  C  C   . LEU A 1 98  ? 81.967  108.376 99.761  1.00 74.05  ? 98  LEU A C   1 
ATOM   756  O  O   . LEU A 1 98  ? 81.900  107.720 100.802 1.00 74.05  ? 98  LEU A O   1 
ATOM   757  C  CB  . LEU A 1 98  ? 83.547  110.294 99.665  1.00 74.05  ? 98  LEU A CB  1 
ATOM   758  C  CG  . LEU A 1 98  ? 83.816  111.784 99.563  1.00 74.05  ? 98  LEU A CG  1 
ATOM   759  C  CD1 . LEU A 1 98  ? 85.294  112.030 99.617  1.00 74.05  ? 98  LEU A CD1 1 
ATOM   760  C  CD2 . LEU A 1 98  ? 83.239  112.319 98.284  1.00 74.05  ? 98  LEU A CD2 1 
ATOM   761  N  N   . PRO A 1 99  ? 81.917  107.786 98.573  1.00 76.51  ? 99  PRO A N   1 
ATOM   762  C  CA  . PRO A 1 99  ? 82.024  106.331 98.473  1.00 76.51  ? 99  PRO A CA  1 
ATOM   763  C  C   . PRO A 1 99  ? 83.460  105.870 98.662  1.00 76.51  ? 99  PRO A C   1 
ATOM   764  O  O   . PRO A 1 99  ? 84.399  106.664 98.705  1.00 76.51  ? 99  PRO A O   1 
ATOM   765  C  CB  . PRO A 1 99  ? 81.533  106.040 97.054  1.00 76.51  ? 99  PRO A CB  1 
ATOM   766  C  CG  . PRO A 1 99  ? 81.771  107.284 96.321  1.00 76.51  ? 99  PRO A CG  1 
ATOM   767  C  CD  . PRO A 1 99  ? 81.536  108.387 97.287  1.00 76.51  ? 99  PRO A CD  1 
ATOM   768  N  N   . ASP A 1 100 ? 83.614  104.559 98.791  1.00 80.37  ? 100 ASP A N   1 
ATOM   769  C  CA  . ASP A 1 100 ? 84.939  103.974 98.921  1.00 80.37  ? 100 ASP A CA  1 
ATOM   770  C  C   . ASP A 1 100 ? 85.697  104.068 97.606  1.00 80.37  ? 100 ASP A C   1 
ATOM   771  O  O   . ASP A 1 100 ? 85.110  104.017 96.525  1.00 80.37  ? 100 ASP A O   1 
ATOM   772  C  CB  . ASP A 1 100 ? 84.834  102.513 99.346  1.00 80.37  ? 100 ASP A CB  1 
ATOM   773  C  CG  . ASP A 1 100 ? 84.912  102.333 100.837 1.00 80.37  ? 100 ASP A CG  1 
ATOM   774  O  OD1 . ASP A 1 100 ? 85.717  103.033 101.478 1.00 80.37  ? 100 ASP A OD1 1 
ATOM   775  O  OD2 . ASP A 1 100 ? 84.172  101.486 101.370 1.00 80.37  ? 100 ASP A OD2 1 
ATOM   776  N  N   . GLY A 1 101 ? 87.004  104.209 97.702  1.00 75.35  ? 101 GLY A N   1 
ATOM   777  C  CA  . GLY A 1 101 ? 87.851  104.133 96.535  1.00 75.35  ? 101 GLY A CA  1 
ATOM   778  C  C   . GLY A 1 101 ? 88.863  105.254 96.523  1.00 75.35  ? 101 GLY A C   1 
ATOM   779  O  O   . GLY A 1 101 ? 89.086  105.925 97.520  1.00 75.35  ? 101 GLY A O   1 
ATOM   780  N  N   . VAL A 1 102 ? 89.473  105.430 95.359  1.00 73.75  ? 102 VAL A N   1 
ATOM   781  C  CA  . VAL A 1 102 ? 90.478  106.456 95.135  1.00 73.75  ? 102 VAL A CA  1 
ATOM   782  C  C   . VAL A 1 102 ? 89.798  107.632 94.456  1.00 73.75  ? 102 VAL A C   1 
ATOM   783  O  O   . VAL A 1 102 ? 89.111  107.463 93.444  1.00 73.75  ? 102 VAL A O   1 
ATOM   784  C  CB  . VAL A 1 102 ? 91.641  105.925 94.287  1.00 73.75  ? 102 VAL A CB  1 
ATOM   785  C  CG1 . VAL A 1 102 ? 92.787  106.886 94.321  1.00 73.75  ? 102 VAL A CG1 1 
ATOM   786  C  CG2 . VAL A 1 102 ? 92.079  104.584 94.794  1.00 73.75  ? 102 VAL A CG2 1 
ATOM   787  N  N   . HIS A 1 103 ? 89.979  108.819 95.013  1.00 72.54  ? 103 HIS A N   1 
ATOM   788  C  CA  . HIS A 1 103 ? 89.359  110.024 94.496  1.00 72.54  ? 103 HIS A CA  1 
ATOM   789  C  C   . HIS A 1 103 ? 90.429  110.997 94.039  1.00 72.54  ? 103 HIS A C   1 
ATOM   790  O  O   . HIS A 1 103 ? 91.479  111.125 94.668  1.00 72.54  ? 103 HIS A O   1 
ATOM   791  C  CB  . HIS A 1 103 ? 88.473  110.682 95.550  1.00 72.54  ? 103 HIS A CB  1 
ATOM   792  C  CG  . HIS A 1 103 ? 87.343  109.820 96.005  1.00 72.54  ? 103 HIS A CG  1 
ATOM   793  N  ND1 . HIS A 1 103 ? 86.209  109.624 95.251  1.00 72.54  ? 103 HIS A ND1 1 
ATOM   794  C  CD2 . HIS A 1 103 ? 87.176  109.093 97.132  1.00 72.54  ? 103 HIS A CD2 1 
ATOM   795  C  CE1 . HIS A 1 103 ? 85.390  108.815 95.896  1.00 72.54  ? 103 HIS A CE1 1 
ATOM   796  N  NE2 . HIS A 1 103 ? 85.955  108.477 97.039  1.00 72.54  ? 103 HIS A NE2 1 
ATOM   797  N  N   . GLU A 1 104 ? 90.157  111.676 92.936  1.00 76.14  ? 104 GLU A N   1 
ATOM   798  C  CA  . GLU A 1 104 ? 91.039  112.716 92.433  1.00 76.14  ? 104 GLU A CA  1 
ATOM   799  C  C   . GLU A 1 104 ? 90.699  114.008 93.158  1.00 76.14  ? 104 GLU A C   1 
ATOM   800  O  O   . GLU A 1 104 ? 89.811  114.750 92.736  1.00 76.14  ? 104 GLU A O   1 
ATOM   801  C  CB  . GLU A 1 104 ? 90.886  112.868 90.927  1.00 76.14  ? 104 GLU A CB  1 
ATOM   802  C  CG  . GLU A 1 104 ? 92.098  113.449 90.259  1.00 76.14  ? 104 GLU A CG  1 
ATOM   803  C  CD  . GLU A 1 104 ? 91.843  113.792 88.814  1.00 76.14  ? 104 GLU A CD  1 
ATOM   804  O  OE1 . GLU A 1 104 ? 90.692  114.136 88.480  1.00 76.14  ? 104 GLU A OE1 1 
ATOM   805  O  OE2 . GLU A 1 104 ? 92.791  113.716 88.008  1.00 76.14  ? 104 GLU A OE2 1 
ATOM   806  N  N   . LEU A 1 105 ? 91.399  114.274 94.248  1.00 71.80  ? 105 LEU A N   1 
ATOM   807  C  CA  . LEU A 1 105 ? 91.102  115.399 95.114  1.00 71.80  ? 105 LEU A CA  1 
ATOM   808  C  C   . LEU A 1 105 ? 91.946  116.590 94.698  1.00 71.80  ? 105 LEU A C   1 
ATOM   809  O  O   . LEU A 1 105 ? 93.174  116.505 94.675  1.00 71.80  ? 105 LEU A O   1 
ATOM   810  C  CB  . LEU A 1 105 ? 91.372  115.030 96.569  1.00 71.80  ? 105 LEU A CB  1 
ATOM   811  C  CG  . LEU A 1 105 ? 91.198  116.098 97.638  1.00 71.80  ? 105 LEU A CG  1 
ATOM   812  C  CD1 . LEU A 1 105 ? 89.822  116.664 97.567  1.00 71.80  ? 105 LEU A CD1 1 
ATOM   813  C  CD2 . LEU A 1 105 ? 91.432  115.498 98.992  1.00 71.80  ? 105 LEU A CD2 1 
ATOM   814  N  N   . SER A 1 106 ? 91.287  117.690 94.362  1.00 72.25  ? 106 SER A N   1 
ATOM   815  C  CA  . SER A 1 106 ? 91.954  118.913 93.945  1.00 72.25  ? 106 SER A CA  1 
ATOM   816  C  C   . SER A 1 106 ? 91.606  120.023 94.917  1.00 72.25  ? 106 SER A C   1 
ATOM   817  O  O   . SER A 1 106 ? 90.429  120.332 95.108  1.00 72.25  ? 106 SER A O   1 
ATOM   818  C  CB  . SER A 1 106 ? 91.537  119.312 92.533  1.00 72.25  ? 106 SER A CB  1 
ATOM   819  O  OG  . SER A 1 106 ? 91.921  118.330 91.594  1.00 72.25  ? 106 SER A OG  1 
ATOM   820  N  N   . ILE A 1 107 ? 92.619  120.622 95.526  1.00 71.42  ? 107 ILE A N   1 
ATOM   821  C  CA  . ILE A 1 107 ? 92.397  121.730 96.439  1.00 71.42  ? 107 ILE A CA  1 
ATOM   822  C  C   . ILE A 1 107 ? 92.938  123.003 95.815  1.00 71.42  ? 107 ILE A C   1 
ATOM   823  O  O   . ILE A 1 107 ? 93.753  122.974 94.890  1.00 71.42  ? 107 ILE A O   1 
ATOM   824  C  CB  . ILE A 1 107 ? 93.025  121.499 97.827  1.00 71.42  ? 107 ILE A CB  1 
ATOM   825  C  CG1 . ILE A 1 107 ? 94.541  121.618 97.754  1.00 71.42  ? 107 ILE A CG1 1 
ATOM   826  C  CG2 . ILE A 1 107 ? 92.607  120.160 98.375  1.00 71.42  ? 107 ILE A CG2 1 
ATOM   827  C  CD1 . ILE A 1 107 ? 95.216  121.591 99.081  1.00 71.42  ? 107 ILE A CD1 1 
ATOM   828  N  N   . GLU A 1 108 ? 92.443  124.131 96.309  1.00 75.63  ? 108 GLU A N   1 
ATOM   829  C  CA  . GLU A 1 108 ? 92.912  125.461 95.925  1.00 75.63  ? 108 GLU A CA  1 
ATOM   830  C  C   . GLU A 1 108 ? 93.052  126.264 97.212  1.00 75.63  ? 108 GLU A C   1 
ATOM   831  O  O   . GLU A 1 108 ? 92.123  126.944 97.645  1.00 75.63  ? 108 GLU A O   1 
ATOM   832  C  CB  . GLU A 1 108 ? 91.965  126.108 94.948  1.00 75.63  ? 108 GLU A CB  1 
ATOM   833  C  CG  . GLU A 1 108 ? 92.453  127.424 94.412  1.00 75.63  ? 108 GLU A CG  1 
ATOM   834  C  CD  . GLU A 1 108 ? 91.326  128.299 93.915  1.00 75.63  ? 108 GLU A CD  1 
ATOM   835  O  OE1 . GLU A 1 108 ? 90.676  127.916 92.921  1.00 75.63  ? 108 GLU A OE1 1 
ATOM   836  O  OE2 . GLU A 1 108 ? 91.087  129.367 94.516  1.00 75.63  ? 108 GLU A OE2 1 
ATOM   837  N  N   . LEU A 1 109 ? 94.221  126.176 97.828  1.00 73.07  ? 109 LEU A N   1 
ATOM   838  C  CA  . LEU A 1 109 ? 94.438  126.790 99.125  1.00 73.07  ? 109 LEU A CA  1 
ATOM   839  C  C   . LEU A 1 109 ? 94.947  128.211 98.965  1.00 73.07  ? 109 LEU A C   1 
ATOM   840  O  O   . LEU A 1 109 ? 95.839  128.475 98.161  1.00 73.07  ? 109 LEU A O   1 
ATOM   841  C  CB  . LEU A 1 109 ? 95.435  125.962 99.925  1.00 73.07  ? 109 LEU A CB  1 
ATOM   842  C  CG  . LEU A 1 109 ? 95.985  126.535 101.221 1.00 73.07  ? 109 LEU A CG  1 
ATOM   843  C  CD1 . LEU A 1 109 ? 94.889  126.691 102.238 1.00 73.07  ? 109 LEU A CD1 1 
ATOM   844  C  CD2 . LEU A 1 109 ? 97.056  125.628 101.736 1.00 73.07  ? 109 LEU A CD2 1 
ATOM   845  N  N   . ARG A 1 110 ? 94.380  129.130 99.737  1.00 75.63  ? 110 ARG A N   1 
ATOM   846  C  CA  . ARG A 1 110 ? 94.757  130.533 99.686  1.00 75.63  ? 110 ARG A CA  1 
ATOM   847  C  C   . ARG A 1 110 ? 95.292  130.979 101.035 1.00 75.63  ? 110 ARG A C   1 
ATOM   848  O  O   . ARG A 1 110 ? 94.637  130.784 102.059 1.00 75.63  ? 110 ARG A O   1 
ATOM   849  C  CB  . ARG A 1 110 ? 93.578  131.405 99.297  1.00 75.63  ? 110 ARG A CB  1 
ATOM   850  C  CG  . ARG A 1 110 ? 92.988  131.088 97.973  1.00 75.63  ? 110 ARG A CG  1 
ATOM   851  C  CD  . ARG A 1 110 ? 91.851  132.023 97.725  1.00 75.63  ? 110 ARG A CD  1 
ATOM   852  N  NE  . ARG A 1 110 ? 91.098  131.666 96.537  1.00 75.63  ? 110 ARG A NE  1 
ATOM   853  C  CZ  . ARG A 1 110 ? 89.985  132.281 96.167  1.00 75.63  ? 110 ARG A CZ  1 
ATOM   854  N  NH1 . ARG A 1 110 ? 89.512  133.276 96.900  1.00 75.63  ? 110 ARG A NH1 1 
ATOM   855  N  NH2 . ARG A 1 110 ? 89.347  131.901 95.073  1.00 75.63  ? 110 ARG A NH2 1 
ATOM   856  N  N   . LEU A 1 111 ? 96.471  131.584 101.030 1.00 74.98  ? 111 LEU A N   1 
ATOM   857  C  CA  . LEU A 1 111 ? 97.079  132.135 102.227 1.00 74.98  ? 111 LEU A CA  1 
ATOM   858  C  C   . LEU A 1 111 ? 97.481  133.569 101.954 1.00 74.98  ? 111 LEU A C   1 
ATOM   859  O  O   . LEU A 1 111 ? 97.883  133.905 100.840 1.00 74.98  ? 111 LEU A O   1 
ATOM   860  C  CB  . LEU A 1 111 ? 98.306  131.340 102.651 1.00 74.98  ? 111 LEU A CB  1 
ATOM   861  C  CG  . LEU A 1 111 ? 98.127  129.855 102.925 1.00 74.98  ? 111 LEU A CG  1 
ATOM   862  C  CD1 . LEU A 1 111 ? 99.468  129.211 103.139 1.00 74.98  ? 111 LEU A CD1 1 
ATOM   863  C  CD2 . LEU A 1 111 ? 97.249  129.657 104.129 1.00 74.98  ? 111 LEU A CD2 1 
ATOM   864  N  N   . ARG A 1 112 ? 97.377  134.415 102.968 1.00 75.82  ? 112 ARG A N   1 
ATOM   865  C  CA  . ARG A 1 112 ? 97.769  135.812 102.850 1.00 75.82  ? 112 ARG A CA  1 
ATOM   866  C  C   . ARG A 1 112 ? 99.156  136.002 103.445 1.00 75.82  ? 112 ARG A C   1 
ATOM   867  O  O   . ARG A 1 112 ? 99.354  135.796 104.644 1.00 75.82  ? 112 ARG A O   1 
ATOM   868  C  CB  . ARG A 1 112 ? 96.762  136.725 103.541 1.00 75.82  ? 112 ARG A CB  1 
ATOM   869  C  CG  . ARG A 1 112 ? 95.375  136.626 102.979 1.00 75.82  ? 112 ARG A CG  1 
ATOM   870  C  CD  . ARG A 1 112 ? 94.542  137.831 103.343 1.00 75.82  ? 112 ARG A CD  1 
ATOM   871  N  NE  . ARG A 1 112 ? 94.621  138.151 104.759 1.00 75.82  ? 112 ARG A NE  1 
ATOM   872  C  CZ  . ARG A 1 112 ? 93.883  137.574 105.697 1.00 75.82  ? 112 ARG A CZ  1 
ATOM   873  N  NH1 . ARG A 1 112 ? 93.011  136.640 105.377 1.00 75.82  ? 112 ARG A NH1 1 
ATOM   874  N  NH2 . ARG A 1 112 ? 94.022  137.931 106.959 1.00 75.82  ? 112 ARG A NH2 1 
ATOM   875  N  N   . MET A 1 113 ? 100.108 136.385 102.607 1.00 81.50  ? 113 MET A N   1 
ATOM   876  C  CA  . MET A 1 113 ? 101.436 136.784 103.040 1.00 81.50  ? 113 MET A CA  1 
ATOM   877  C  C   . MET A 1 113 ? 101.494 138.302 103.003 1.00 81.50  ? 113 MET A C   1 
ATOM   878  O  O   . MET A 1 113 ? 101.193 138.907 101.973 1.00 81.50  ? 113 MET A O   1 
ATOM   879  C  CB  . MET A 1 113 ? 102.508 136.187 102.136 1.00 81.50  ? 113 MET A CB  1 
ATOM   880  C  CG  . MET A 1 113 ? 102.234 134.777 101.679 1.00 81.50  ? 113 MET A CG  1 
ATOM   881  S  SD  . MET A 1 113 ? 102.262 133.588 103.017 1.00 81.50  ? 113 MET A SD  1 
ATOM   882  C  CE  . MET A 1 113 ? 101.974 132.078 102.113 1.00 81.50  ? 113 MET A CE  1 
ATOM   883  N  N   . SER A 1 114 ? 101.868 138.916 104.120 1.00 82.64  ? 114 SER A N   1 
ATOM   884  C  CA  . SER A 1 114 ? 101.798 140.368 104.205 1.00 82.64  ? 114 SER A CA  1 
ATOM   885  C  C   . SER A 1 114 ? 102.962 141.056 103.512 1.00 82.64  ? 114 SER A C   1 
ATOM   886  O  O   . SER A 1 114 ? 102.849 142.231 103.161 1.00 82.64  ? 114 SER A O   1 
ATOM   887  C  CB  . SER A 1 114 ? 101.736 140.801 105.664 1.00 82.64  ? 114 SER A CB  1 
ATOM   888  O  OG  . SER A 1 114 ? 100.824 139.994 106.377 1.00 82.64  ? 114 SER A OG  1 
ATOM   889  N  N   . TYR A 1 115 ? 104.063 140.357 103.293 1.00 82.52  ? 115 TYR A N   1 
ATOM   890  C  CA  . TYR A 1 115 ? 105.259 140.938 102.704 1.00 82.52  ? 115 TYR A CA  1 
ATOM   891  C  C   . TYR A 1 115 ? 105.251 140.894 101.185 1.00 82.52  ? 115 TYR A C   1 
ATOM   892  O  O   . TYR A 1 115 ? 106.232 141.302 100.563 1.00 82.52  ? 115 TYR A O   1 
ATOM   893  C  CB  . TYR A 1 115 ? 106.503 140.222 103.239 1.00 82.52  ? 115 TYR A CB  1 
ATOM   894  C  CG  . TYR A 1 115 ? 106.386 138.718 103.264 1.00 82.52  ? 115 TYR A CG  1 
ATOM   895  C  CD1 . TYR A 1 115 ? 106.703 137.965 102.149 1.00 82.52  ? 115 TYR A CD1 1 
ATOM   896  C  CD2 . TYR A 1 115 ? 105.969 138.053 104.407 1.00 82.52  ? 115 TYR A CD2 1 
ATOM   897  C  CE1 . TYR A 1 115 ? 106.597 136.605 102.164 1.00 82.52  ? 115 TYR A CE1 1 
ATOM   898  C  CE2 . TYR A 1 115 ? 105.853 136.692 104.427 1.00 82.52  ? 115 TYR A CE2 1 
ATOM   899  C  CZ  . TYR A 1 115 ? 106.169 135.975 103.303 1.00 82.52  ? 115 TYR A CZ  1 
ATOM   900  O  OH  . TYR A 1 115 ? 106.069 134.608 103.319 1.00 82.52  ? 115 TYR A OH  1 
ATOM   901  N  N   . ILE A 1 116 ? 104.177 140.407 100.581 1.00 85.75  ? 116 ILE A N   1 
ATOM   902  C  CA  . ILE A 1 116 ? 104.033 140.308 99.133  1.00 85.75  ? 116 ILE A CA  1 
ATOM   903  C  C   . ILE A 1 116 ? 103.079 141.422 98.719  1.00 85.75  ? 116 ILE A C   1 
ATOM   904  O  O   . ILE A 1 116 ? 102.141 141.714 99.471  1.00 85.75  ? 116 ILE A O   1 
ATOM   905  C  CB  . ILE A 1 116 ? 103.536 138.906 98.741  1.00 85.75  ? 116 ILE A CB  1 
ATOM   906  C  CG1 . ILE A 1 116 ? 104.606 137.873 99.079  1.00 85.75  ? 116 ILE A CG1 1 
ATOM   907  C  CG2 . ILE A 1 116 ? 103.171 138.805 97.275  1.00 85.75  ? 116 ILE A CG2 1 
ATOM   908  C  CD1 . ILE A 1 116 ? 104.207 136.464 98.775  1.00 85.75  ? 116 ILE A CD1 1 
ATOM   909  N  N   . PRO A 1 117 ? 103.313 142.111 97.595  1.00 90.50  ? 117 PRO A N   1 
ATOM   910  C  CA  . PRO A 1 117 ? 102.394 143.172 97.164  1.00 90.50  ? 117 PRO A CA  1 
ATOM   911  C  C   . PRO A 1 117 ? 100.994 142.656 96.877  1.00 90.50  ? 117 PRO A C   1 
ATOM   912  O  O   . PRO A 1 117 ? 100.794 141.482 96.574  1.00 90.50  ? 117 PRO A O   1 
ATOM   913  C  CB  . PRO A 1 117 ? 103.054 143.707 95.893  1.00 90.50  ? 117 PRO A CB  1 
ATOM   914  C  CG  . PRO A 1 117 ? 104.473 143.437 96.082  1.00 90.50  ? 117 PRO A CG  1 
ATOM   915  C  CD  . PRO A 1 117 ? 104.567 142.146 96.826  1.00 90.50  ? 117 PRO A CD  1 
ATOM   916  N  N   . GLN A 1 118 ? 100.028 143.571 96.960  1.00 93.45  ? 118 GLN A N   1 
ATOM   917  C  CA  . GLN A 1 118 ? 98.617  143.203 96.994  1.00 93.45  ? 118 GLN A CA  1 
ATOM   918  C  C   . GLN A 1 118 ? 98.119  142.653 95.663  1.00 93.45  ? 118 GLN A C   1 
ATOM   919  O  O   . GLN A 1 118 ? 97.133  141.910 95.632  1.00 93.45  ? 118 GLN A O   1 
ATOM   920  C  CB  . GLN A 1 118 ? 97.796  144.421 97.403  1.00 93.45  ? 118 GLN A CB  1 
ATOM   921  C  CG  . GLN A 1 118 ? 96.407  144.121 97.900  1.00 93.45  ? 118 GLN A CG  1 
ATOM   922  C  CD  . GLN A 1 118 ? 96.400  143.594 99.307  1.00 93.45  ? 118 GLN A CD  1 
ATOM   923  O  OE1 . GLN A 1 118 ? 96.682  144.324 100.255 1.00 93.45  ? 118 GLN A OE1 1 
ATOM   924  N  NE2 . GLN A 1 118 ? 96.069  142.318 99.458  1.00 93.45  ? 118 GLN A NE2 1 
ATOM   925  N  N   . GLU A 1 119 ? 98.787  142.987 94.559  1.00 96.43  ? 119 GLU A N   1 
ATOM   926  C  CA  . GLU A 1 119 ? 98.315  142.534 93.254  1.00 96.43  ? 119 GLU A CA  1 
ATOM   927  C  C   . GLU A 1 119 ? 98.591  141.051 93.042  1.00 96.43  ? 119 GLU A C   1 
ATOM   928  O  O   . GLU A 1 119 ? 97.869  140.379 92.300  1.00 96.43  ? 119 GLU A O   1 
ATOM   929  C  CB  . GLU A 1 119 ? 98.962  143.361 92.146  1.00 96.43  ? 119 GLU A CB  1 
ATOM   930  C  CG  . GLU A 1 119 ? 100.469 143.457 92.244  1.00 96.43  ? 119 GLU A CG  1 
ATOM   931  C  CD  . GLU A 1 119 ? 100.929 144.731 92.918  1.00 96.43  ? 119 GLU A CD  1 
ATOM   932  O  OE1 . GLU A 1 119 ? 100.393 145.066 93.995  1.00 96.43  ? 119 GLU A OE1 1 
ATOM   933  O  OE2 . GLU A 1 119 ? 101.828 145.397 92.370  1.00 96.43  ? 119 GLU A OE2 1 
ATOM   934  N  N   . HIS A 1 120 ? 99.624  140.523 93.683  1.00 94.31  ? 120 HIS A N   1 
ATOM   935  C  CA  . HIS A 1 120 ? 99.956  139.112 93.584  1.00 94.31  ? 120 HIS A CA  1 
ATOM   936  C  C   . HIS A 1 120 ? 99.376  138.293 94.723  1.00 94.31  ? 120 HIS A C   1 
ATOM   937  O  O   . HIS A 1 120 ? 99.883  137.207 95.007  1.00 94.31  ? 120 HIS A O   1 
ATOM   938  C  CB  . HIS A 1 120 ? 101.470 138.934 93.547  1.00 94.31  ? 120 HIS A CB  1 
ATOM   939  C  CG  . HIS A 1 120 ? 102.124 139.606 92.385  1.00 94.31  ? 120 HIS A CG  1 
ATOM   940  N  ND1 . HIS A 1 120 ? 103.341 140.243 92.483  1.00 94.31  ? 120 HIS A ND1 1 
ATOM   941  C  CD2 . HIS A 1 120 ? 101.728 139.746 91.099  1.00 94.31  ? 120 HIS A CD2 1 
ATOM   942  C  CE1 . HIS A 1 120 ? 103.669 140.743 91.306  1.00 94.31  ? 120 HIS A CE1 1 
ATOM   943  N  NE2 . HIS A 1 120 ? 102.707 140.456 90.449  1.00 94.31  ? 120 HIS A NE2 1 
ATOM   944  N  N   . GLN A 1 121 ? 98.335  138.780 95.370  1.00 85.71  ? 121 GLN A N   1 
ATOM   945  C  CA  . GLN A 1 121 ? 97.805  138.192 96.581  1.00 85.71  ? 121 GLN A CA  1 
ATOM   946  C  C   . GLN A 1 121 ? 96.340  137.822 96.409  1.00 85.71  ? 121 GLN A C   1 
ATOM   947  O  O   . GLN A 1 121 ? 95.609  138.487 95.672  1.00 85.71  ? 121 GLN A O   1 
ATOM   948  C  CB  . GLN A 1 121 ? 97.969  139.175 97.743  1.00 85.71  ? 121 GLN A CB  1 
ATOM   949  C  CG  . GLN A 1 121 ? 99.341  139.140 98.356  1.00 85.71  ? 121 GLN A CG  1 
ATOM   950  C  CD  . GLN A 1 121 ? 99.662  137.811 98.977  1.00 85.71  ? 121 GLN A CD  1 
ATOM   951  O  OE1 . GLN A 1 121 ? 100.546 137.093 98.522  1.00 85.71  ? 121 GLN A OE1 1 
ATOM   952  N  NE2 . GLN A 1 121 ? 98.945  137.475 100.029 1.00 85.71  ? 121 GLN A NE2 1 
ATOM   953  N  N   . PRO A 1 122 ? 95.863  136.759 97.077  1.00 79.98  ? 122 PRO A N   1 
ATOM   954  C  CA  . PRO A 1 122 ? 96.540  135.845 97.998  1.00 79.98  ? 122 PRO A CA  1 
ATOM   955  C  C   . PRO A 1 122 ? 97.380  134.796 97.301  1.00 79.98  ? 122 PRO A C   1 
ATOM   956  O  O   . PRO A 1 122 ? 97.194  134.554 96.116  1.00 79.98  ? 122 PRO A O   1 
ATOM   957  C  CB  . PRO A 1 122 ? 95.384  135.194 98.741  1.00 79.98  ? 122 PRO A CB  1 
ATOM   958  C  CG  . PRO A 1 122 ? 94.299  135.199 97.780  1.00 79.98  ? 122 PRO A CG  1 
ATOM   959  C  CD  . PRO A 1 122 ? 94.426  136.463 97.003  1.00 79.98  ? 122 PRO A CD  1 
ATOM   960  N  N   . SER A 1 123 ? 98.316  134.211 98.037  1.00 77.83  ? 123 SER A N   1 
ATOM   961  C  CA  . SER A 1 123 ? 99.113  133.117 97.513  1.00 77.83  ? 123 SER A CA  1 
ATOM   962  C  C   . SER A 1 123 ? 98.237  131.891 97.330  1.00 77.83  ? 123 SER A C   1 
ATOM   963  O  O   . SER A 1 123 ? 97.563  131.456 98.260  1.00 77.83  ? 123 SER A O   1 
ATOM   964  C  CB  . SER A 1 123 ? 100.262 132.802 98.460  1.00 77.83  ? 123 SER A CB  1 
ATOM   965  O  OG  . SER A 1 123 ? 101.182 133.870 98.509  1.00 77.83  ? 123 SER A OG  1 
ATOM   966  N  N   . THR A 1 124 ? 98.246  131.333 96.130  1.00 75.03  ? 124 THR A N   1 
ATOM   967  C  CA  . THR A 1 124 ? 97.368  130.233 95.773  1.00 75.03  ? 124 THR A CA  1 
ATOM   968  C  C   . THR A 1 124 ? 98.202  128.985 95.542  1.00 75.03  ? 124 THR A C   1 
ATOM   969  O  O   . THR A 1 124 ? 99.236  129.043 94.874  1.00 75.03  ? 124 THR A O   1 
ATOM   970  C  CB  . THR A 1 124 ? 96.552  130.575 94.528  1.00 75.03  ? 124 THR A CB  1 
ATOM   971  O  OG1 . THR A 1 124 ? 95.934  131.852 94.705  1.00 75.03  ? 124 THR A OG1 1 
ATOM   972  C  CG2 . THR A 1 124 ? 95.473  129.559 94.311  1.00 75.03  ? 124 THR A CG2 1 
ATOM   973  N  N   . TYR A 1 125 ? 97.764  127.870 96.109  1.00 73.63  ? 125 TYR A N   1 
ATOM   974  C  CA  . TYR A 1 125 ? 98.431  126.587 95.955  1.00 73.63  ? 125 TYR A CA  1 
ATOM   975  C  C   . TYR A 1 125 ? 97.414  125.587 95.439  1.00 73.63  ? 125 TYR A C   1 
ATOM   976  O  O   . TYR A 1 125 ? 96.469  125.242 96.149  1.00 73.63  ? 125 TYR A O   1 
ATOM   977  C  CB  . TYR A 1 125 ? 99.021  126.106 97.279  1.00 73.63  ? 125 TYR A CB  1 
ATOM   978  C  CG  . TYR A 1 125 ? 99.994  127.065 97.908  1.00 73.63  ? 125 TYR A CG  1 
ATOM   979  C  CD1 . TYR A 1 125 ? 99.564  128.037 98.796  1.00 73.63  ? 125 TYR A CD1 1 
ATOM   980  C  CD2 . TYR A 1 125 ? 101.343 126.992 97.622  1.00 73.63  ? 125 TYR A CD2 1 
ATOM   981  C  CE1 . TYR A 1 125 ? 100.447 128.914 99.368  1.00 73.63  ? 125 TYR A CE1 1 
ATOM   982  C  CE2 . TYR A 1 125 ? 102.235 127.864 98.193  1.00 73.63  ? 125 TYR A CE2 1 
ATOM   983  C  CZ  . TYR A 1 125 ? 101.780 128.821 99.065  1.00 73.63  ? 125 TYR A CZ  1 
ATOM   984  O  OH  . TYR A 1 125 ? 102.669 129.693 99.638  1.00 73.63  ? 125 TYR A OH  1 
ATOM   985  N  N   . ARG A 1 126 ? 97.601  125.130 94.211  1.00 76.66  ? 126 ARG A N   1 
ATOM   986  C  CA  . ARG A 1 126 ? 96.718  124.149 93.599  1.00 76.66  ? 126 ARG A CA  1 
ATOM   987  C  C   . ARG A 1 126 ? 97.469  122.841 93.449  1.00 76.66  ? 126 ARG A C   1 
ATOM   988  O  O   . ARG A 1 126 ? 98.424  122.760 92.673  1.00 76.66  ? 126 ARG A O   1 
ATOM   989  C  CB  . ARG A 1 126 ? 96.226  124.622 92.236  1.00 76.66  ? 126 ARG A CB  1 
ATOM   990  C  CG  . ARG A 1 126 ? 95.447  125.893 92.271  1.00 76.66  ? 126 ARG A CG  1 
ATOM   991  C  CD  . ARG A 1 126 ? 95.156  126.359 90.874  1.00 76.66  ? 126 ARG A CD  1 
ATOM   992  N  NE  . ARG A 1 126 ? 95.141  127.811 90.806  1.00 76.66  ? 126 ARG A NE  1 
ATOM   993  C  CZ  . ARG A 1 126 ? 94.037  128.544 90.864  1.00 76.66  ? 126 ARG A CZ  1 
ATOM   994  N  NH1 . ARG A 1 126 ? 92.857  127.954 90.983  1.00 76.66  ? 126 ARG A NH1 1 
ATOM   995  N  NH2 . ARG A 1 126 ? 94.114  129.864 90.801  1.00 76.66  ? 126 ARG A NH2 1 
ATOM   996  N  N   . VAL A 1 127 ? 97.048  121.824 94.188  1.00 73.68  ? 127 VAL A N   1 
ATOM   997  C  CA  . VAL A 1 127 ? 97.596  120.489 94.019  1.00 73.68  ? 127 VAL A CA  1 
ATOM   998  C  C   . VAL A 1 127 ? 96.454  119.521 93.767  1.00 73.68  ? 127 VAL A C   1 
ATOM   999  O  O   . VAL A 1 127 ? 95.306  119.765 94.144  1.00 73.68  ? 127 VAL A O   1 
ATOM   1000 C  CB  . VAL A 1 127 ? 98.441  120.031 95.225  1.00 73.68  ? 127 VAL A CB  1 
ATOM   1001 C  CG1 . VAL A 1 127 ? 99.663  120.901 95.373  1.00 73.68  ? 127 VAL A CG1 1 
ATOM   1002 C  CG2 . VAL A 1 127 ? 97.637  120.073 96.480  1.00 73.68  ? 127 VAL A CG2 1 
ATOM   1003 N  N   . THR A 1 128 ? 96.781  118.424 93.102  1.00 73.96  ? 128 THR A N   1 
ATOM   1004 C  CA  . THR A 1 128 ? 95.850  117.344 92.832  1.00 73.96  ? 128 THR A CA  1 
ATOM   1005 C  C   . THR A 1 128 ? 96.514  116.046 93.246  1.00 73.96  ? 128 THR A C   1 
ATOM   1006 O  O   . THR A 1 128 ? 97.667  115.797 92.892  1.00 73.96  ? 128 THR A O   1 
ATOM   1007 C  CB  . THR A 1 128 ? 95.463  117.300 91.352  1.00 73.96  ? 128 THR A CB  1 
ATOM   1008 O  OG1 . THR A 1 128 ? 94.886  118.552 90.971  1.00 73.96  ? 128 THR A OG1 1 
ATOM   1009 C  CG2 . THR A 1 128 ? 94.463  116.206 91.085  1.00 73.96  ? 128 THR A CG2 1 
ATOM   1010 N  N   . LYS A 1 129 ? 95.803  115.231 94.009  1.00 72.67  ? 129 LYS A N   1 
ATOM   1011 C  CA  . LYS A 1 129 ? 96.335  113.950 94.427  1.00 72.67  ? 129 LYS A CA  1 
ATOM   1012 C  C   . LYS A 1 129 ? 95.239  112.909 94.333  1.00 72.67  ? 129 LYS A C   1 
ATOM   1013 O  O   . LYS A 1 129 ? 94.072  113.195 94.594  1.00 72.67  ? 129 LYS A O   1 
ATOM   1014 C  CB  . LYS A 1 129 ? 96.886  114.011 95.850  1.00 72.67  ? 129 LYS A CB  1 
ATOM   1015 C  CG  . LYS A 1 129 ? 97.745  112.834 96.222  1.00 72.67  ? 129 LYS A CG  1 
ATOM   1016 C  CD  . LYS A 1 129 ? 98.283  112.957 97.612  1.00 72.67  ? 129 LYS A CD  1 
ATOM   1017 C  CE  . LYS A 1 129 ? 98.789  111.630 98.100  1.00 72.67  ? 129 LYS A CE  1 
ATOM   1018 N  NZ  . LYS A 1 129 ? 99.458  111.765 99.406  1.00 72.67  ? 129 LYS A NZ  1 
ATOM   1019 N  N   . HIS A 1 130 ? 95.616  111.704 93.932  1.00 73.58  ? 130 HIS A N   1 
ATOM   1020 C  CA  . HIS A 1 130 ? 94.733  110.554 94.027  1.00 73.58  ? 130 HIS A CA  1 
ATOM   1021 C  C   . HIS A 1 130 ? 94.887  109.952 95.414  1.00 73.58  ? 130 HIS A C   1 
ATOM   1022 O  O   . HIS A 1 130 ? 95.879  109.280 95.696  1.00 73.58  ? 130 HIS A O   1 
ATOM   1023 C  CB  . HIS A 1 130 ? 95.053  109.531 92.948  1.00 73.58  ? 130 HIS A CB  1 
ATOM   1024 C  CG  . HIS A 1 130 ? 94.462  109.862 91.619  1.00 73.58  ? 130 HIS A CG  1 
ATOM   1025 N  ND1 . HIS A 1 130 ? 95.176  110.488 90.625  1.00 73.58  ? 130 HIS A ND1 1 
ATOM   1026 C  CD2 . HIS A 1 130 ? 93.223  109.654 91.121  1.00 73.58  ? 130 HIS A CD2 1 
ATOM   1027 C  CE1 . HIS A 1 130 ? 94.403  110.652 89.570  1.00 73.58  ? 130 HIS A CE1 1 
ATOM   1028 N  NE2 . HIS A 1 130 ? 93.212  110.154 89.844  1.00 73.58  ? 130 HIS A NE2 1 
ATOM   1029 N  N   . VAL A 1 131 ? 93.917  110.206 96.277  1.00 71.01  ? 131 VAL A N   1 
ATOM   1030 C  CA  . VAL A 1 131 ? 93.950  109.742 97.653  1.00 71.01  ? 131 VAL A CA  1 
ATOM   1031 C  C   . VAL A 1 131 ? 92.885  108.679 97.835  1.00 71.01  ? 131 VAL A C   1 
ATOM   1032 O  O   . VAL A 1 131 ? 91.839  108.704 97.184  1.00 71.01  ? 131 VAL A O   1 
ATOM   1033 C  CB  . VAL A 1 131 ? 93.743  110.897 98.651  1.00 71.01  ? 131 VAL A CB  1 
ATOM   1034 C  CG1 . VAL A 1 131 ? 95.019  111.653 98.844  1.00 71.01  ? 131 VAL A CG1 1 
ATOM   1035 C  CG2 . VAL A 1 131 ? 92.684  111.834 98.139  1.00 71.01  ? 131 VAL A CG2 1 
ATOM   1036 N  N   . THR A 1 132 ? 93.157  107.741 98.729  1.00 70.82  ? 132 THR A N   1 
ATOM   1037 C  CA  . THR A 1 132 ? 92.237  106.660 99.037  1.00 70.82  ? 132 THR A CA  1 
ATOM   1038 C  C   . THR A 1 132 ? 91.467  106.997 100.299 1.00 70.82  ? 132 THR A C   1 
ATOM   1039 O  O   . THR A 1 132 ? 92.062  107.396 101.302 1.00 70.82  ? 132 THR A O   1 
ATOM   1040 C  CB  . THR A 1 132 ? 92.985  105.347 99.227  1.00 70.82  ? 132 THR A CB  1 
ATOM   1041 O  OG1 . THR A 1 132 ? 93.979  105.229 98.212  1.00 70.82  ? 132 THR A OG1 1 
ATOM   1042 C  CG2 . THR A 1 132 ? 92.043  104.186 99.126  1.00 70.82  ? 132 THR A CG2 1 
ATOM   1043 N  N   . LEU A 1 133 ? 90.152  106.845 100.243 1.00 71.78  ? 133 LEU A N   1 
ATOM   1044 C  CA  . LEU A 1 133 ? 89.336  107.035 101.428 1.00 71.78  ? 133 LEU A CA  1 
ATOM   1045 C  C   . LEU A 1 133 ? 89.611  105.920 102.419 1.00 71.78  ? 133 LEU A C   1 
ATOM   1046 O  O   . LEU A 1 133 ? 89.870  104.781 102.027 1.00 71.78  ? 133 LEU A O   1 
ATOM   1047 C  CB  . LEU A 1 133 ? 87.859  107.060 101.055 1.00 71.78  ? 133 LEU A CB  1 
ATOM   1048 C  CG  . LEU A 1 133 ? 86.912  107.646 102.092 1.00 71.78  ? 133 LEU A CG  1 
ATOM   1049 C  CD1 . LEU A 1 133 ? 86.939  109.144 102.037 1.00 71.78  ? 133 LEU A CD1 1 
ATOM   1050 C  CD2 . LEU A 1 133 ? 85.522  107.139 101.862 1.00 71.78  ? 133 LEU A CD2 1 
ATOM   1051 N  N   . ALA A 1 134 ? 89.612  106.268 103.698 1.00 71.98  ? 134 ALA A N   1 
ATOM   1052 C  CA  . ALA A 1 134 ? 89.665  105.265 104.744 1.00 71.98  ? 134 ALA A CA  1 
ATOM   1053 C  C   . ALA A 1 134 ? 88.431  104.379 104.638 1.00 71.98  ? 134 ALA A C   1 
ATOM   1054 O  O   . ALA A 1 134 ? 87.321  104.898 104.480 1.00 71.98  ? 134 ALA A O   1 
ATOM   1055 C  CB  . ALA A 1 134 ? 89.733  105.921 106.119 1.00 71.98  ? 134 ALA A CB  1 
ATOM   1056 N  N   . PRO A 1 135 ? 88.585  103.058 104.691 1.00 76.14  ? 135 PRO A N   1 
ATOM   1057 C  CA  . PRO A 1 135 ? 87.532  102.158 104.204 1.00 76.14  ? 135 PRO A CA  1 
ATOM   1058 C  C   . PRO A 1 135 ? 86.279  102.150 105.061 1.00 76.14  ? 135 PRO A C   1 
ATOM   1059 O  O   . PRO A 1 135 ? 86.322  101.881 106.262 1.00 76.14  ? 135 PRO A O   1 
ATOM   1060 C  CB  . PRO A 1 135 ? 88.221  100.791 104.211 1.00 76.14  ? 135 PRO A CB  1 
ATOM   1061 C  CG  . PRO A 1 135 ? 89.664  101.087 104.213 1.00 76.14  ? 135 PRO A CG  1 
ATOM   1062 C  CD  . PRO A 1 135 ? 89.825  102.331 104.991 1.00 76.14  ? 135 PRO A CD  1 
ATOM   1063 N  N   . GLU A 1 136 ? 85.155  102.478 104.426 1.00 82.73  ? 136 GLU A N   1 
ATOM   1064 C  CA  . GLU A 1 136 ? 83.860  102.348 105.073 1.00 82.73  ? 136 GLU A CA  1 
ATOM   1065 C  C   . GLU A 1 136 ? 83.400  100.904 105.089 1.00 82.73  ? 136 GLU A C   1 
ATOM   1066 O  O   . GLU A 1 136 ? 82.506  100.543 105.861 1.00 82.73  ? 136 GLU A O   1 
ATOM   1067 C  CB  . GLU A 1 136 ? 82.829  103.219 104.360 1.00 82.73  ? 136 GLU A CB  1 
ATOM   1068 C  CG  . GLU A 1 136 ? 83.079  104.701 104.494 1.00 82.73  ? 136 GLU A CG  1 
ATOM   1069 C  CD  . GLU A 1 136 ? 82.861  105.196 105.907 1.00 82.73  ? 136 GLU A CD  1 
ATOM   1070 O  OE1 . GLU A 1 136 ? 83.751  105.887 106.443 1.00 82.73  ? 136 GLU A OE1 1 
ATOM   1071 O  OE2 . GLU A 1 136 ? 81.800  104.891 106.486 1.00 82.73  ? 136 GLU A OE2 1 
ATOM   1072 N  N   . ALA A 1 137 ? 83.997  100.076 104.243 1.00 82.50  ? 137 ALA A N   1 
ATOM   1073 C  CA  . ALA A 1 137 ? 83.627  98.677  104.150 1.00 82.50  ? 137 ALA A CA  1 
ATOM   1074 C  C   . ALA A 1 137 ? 84.109  97.913  105.373 1.00 82.50  ? 137 ALA A C   1 
ATOM   1075 O  O   . ALA A 1 137 ? 85.279  97.994  105.755 1.00 82.50  ? 137 ALA A O   1 
ATOM   1076 C  CB  . ALA A 1 137 ? 84.222  98.079  102.882 1.00 82.50  ? 137 ALA A CB  1 
ATOM   1077 N  N   . SER A 1 138 ? 83.199  97.172  105.993 1.00 84.87  ? 138 SER A N   1 
ATOM   1078 C  CA  . SER A 1 138 ? 83.546  96.318  107.120 1.00 84.87  ? 138 SER A CA  1 
ATOM   1079 C  C   . SER A 1 138 ? 83.861  94.914  106.638 1.00 84.87  ? 138 SER A C   1 
ATOM   1080 O  O   . SER A 1 138 ? 82.963  94.070  106.558 1.00 84.87  ? 138 SER A O   1 
ATOM   1081 C  CB  . SER A 1 138 ? 82.405  96.282  108.130 1.00 84.87  ? 138 SER A CB  1 
ATOM   1082 O  OG  . SER A 1 138 ? 82.567  95.200  109.028 1.00 84.87  ? 138 SER A OG  1 
ATOM   1083 N  N   . GLY A 1 139 ? 85.128  94.648  106.331 1.00 81.41  ? 139 GLY A N   1 
ATOM   1084 C  CA  . GLY A 1 139 ? 85.483  93.413  105.666 1.00 81.41  ? 139 GLY A CA  1 
ATOM   1085 C  C   . GLY A 1 139 ? 85.486  92.171  106.522 1.00 81.41  ? 139 GLY A C   1 
ATOM   1086 O  O   . GLY A 1 139 ? 86.512  91.501  106.616 1.00 81.41  ? 139 GLY A O   1 
ATOM   1087 N  N   . ALA A 1 140 ? 84.362  91.846  107.144 1.00 82.23  ? 140 ALA A N   1 
ATOM   1088 C  CA  . ALA A 1 140 ? 84.232  90.600  107.876 1.00 82.23  ? 140 ALA A CA  1 
ATOM   1089 C  C   . ALA A 1 140 ? 84.265  89.424  106.900 1.00 82.23  ? 140 ALA A C   1 
ATOM   1090 O  O   . ALA A 1 140 ? 83.813  89.551  105.760 1.00 82.23  ? 140 ALA A O   1 
ATOM   1091 C  CB  . ALA A 1 140 ? 82.927  90.603  108.669 1.00 82.23  ? 140 ALA A CB  1 
ATOM   1092 N  N   . PRO A 1 141 ? 84.787  88.257  107.313 1.00 79.57  ? 141 PRO A N   1 
ATOM   1093 C  CA  . PRO A 1 141 ? 85.236  87.782  108.621 1.00 79.57  ? 141 PRO A CA  1 
ATOM   1094 C  C   . PRO A 1 141 ? 86.701  88.013  108.938 1.00 79.57  ? 141 PRO A C   1 
ATOM   1095 O  O   . PRO A 1 141 ? 87.139  87.620  110.012 1.00 79.57  ? 141 PRO A O   1 
ATOM   1096 C  CB  . PRO A 1 141 ? 84.965  86.293  108.528 1.00 79.57  ? 141 PRO A CB  1 
ATOM   1097 C  CG  . PRO A 1 141 ? 85.286  85.987  107.122 1.00 79.57  ? 141 PRO A CG  1 
ATOM   1098 C  CD  . PRO A 1 141 ? 84.879  87.184  106.312 1.00 79.57  ? 141 PRO A CD  1 
ATOM   1099 N  N   . PHE A 1 142 ? 87.449  88.629  108.036 1.00 77.55  ? 142 PHE A N   1 
ATOM   1100 C  CA  . PHE A 1 142 ? 88.876  88.752  108.252 1.00 77.55  ? 142 PHE A CA  1 
ATOM   1101 C  C   . PHE A 1 142 ? 89.185  89.894  109.207 1.00 77.55  ? 142 PHE A C   1 
ATOM   1102 O  O   . PHE A 1 142 ? 88.398  90.822  109.384 1.00 77.55  ? 142 PHE A O   1 
ATOM   1103 C  CB  . PHE A 1 142 ? 89.604  88.975  106.931 1.00 77.55  ? 142 PHE A CB  1 
ATOM   1104 C  CG  . PHE A 1 142 ? 89.208  88.019  105.856 1.00 77.55  ? 142 PHE A CG  1 
ATOM   1105 C  CD1 . PHE A 1 142 ? 89.521  86.681  105.955 1.00 77.55  ? 142 PHE A CD1 1 
ATOM   1106 C  CD2 . PHE A 1 142 ? 88.526  88.459  104.741 1.00 77.55  ? 142 PHE A CD2 1 
ATOM   1107 C  CE1 . PHE A 1 142 ? 89.158  85.802  104.967 1.00 77.55  ? 142 PHE A CE1 1 
ATOM   1108 C  CE2 . PHE A 1 142 ? 88.161  87.582  103.751 1.00 77.55  ? 142 PHE A CE2 1 
ATOM   1109 C  CZ  . PHE A 1 142 ? 88.478  86.253  103.866 1.00 77.55  ? 142 PHE A CZ  1 
ATOM   1110 N  N   . ARG A 1 143 ? 90.345  89.803  109.838 1.00 75.82  ? 143 ARG A N   1 
ATOM   1111 C  CA  . ARG A 1 143 ? 90.924  90.898  110.593 1.00 75.82  ? 143 ARG A CA  1 
ATOM   1112 C  C   . ARG A 1 143 ? 92.038  91.499  109.758 1.00 75.82  ? 143 ARG A C   1 
ATOM   1113 O  O   . ARG A 1 143 ? 92.612  90.826  108.904 1.00 75.82  ? 143 ARG A O   1 
ATOM   1114 C  CB  . ARG A 1 143 ? 91.461  90.421  111.936 1.00 75.82  ? 143 ARG A CB  1 
ATOM   1115 C  CG  . ARG A 1 143 ? 90.708  89.246  112.498 1.00 75.82  ? 143 ARG A CG  1 
ATOM   1116 C  CD  . ARG A 1 143 ? 90.842  89.200  113.985 1.00 75.82  ? 143 ARG A CD  1 
ATOM   1117 N  NE  . ARG A 1 143 ? 90.439  90.467  114.572 1.00 75.82  ? 143 ARG A NE  1 
ATOM   1118 C  CZ  . ARG A 1 143 ? 90.948  90.961  115.692 1.00 75.82  ? 143 ARG A CZ  1 
ATOM   1119 N  NH1 . ARG A 1 143 ? 91.883  90.290  116.348 1.00 75.82  ? 143 ARG A NH1 1 
ATOM   1120 N  NH2 . ARG A 1 143 ? 90.524  92.127  116.156 1.00 75.82  ? 143 ARG A NH2 1 
ATOM   1121 N  N   . TYR A 1 144 ? 92.341  92.764  109.990 1.00 73.84  ? 144 TYR A N   1 
ATOM   1122 C  CA  . TYR A 1 144 ? 93.192  93.506  109.079 1.00 73.84  ? 144 TYR A CA  1 
ATOM   1123 C  C   . TYR A 1 144 ? 94.384  94.082  109.816 1.00 73.84  ? 144 TYR A C   1 
ATOM   1124 O  O   . TYR A 1 144 ? 94.242  94.652  110.897 1.00 73.84  ? 144 TYR A O   1 
ATOM   1125 C  CB  . TYR A 1 144 ? 92.391  94.599  108.379 1.00 73.84  ? 144 TYR A CB  1 
ATOM   1126 C  CG  . TYR A 1 144 ? 91.340  93.995  107.494 1.00 73.84  ? 144 TYR A CG  1 
ATOM   1127 C  CD1 . TYR A 1 144 ? 91.652  93.567  106.218 1.00 73.84  ? 144 TYR A CD1 1 
ATOM   1128 C  CD2 . TYR A 1 144 ? 90.052  93.793  107.954 1.00 73.84  ? 144 TYR A CD2 1 
ATOM   1129 C  CE1 . TYR A 1 144 ? 90.710  92.987  105.424 1.00 73.84  ? 144 TYR A CE1 1 
ATOM   1130 C  CE2 . TYR A 1 144 ? 89.111  93.213  107.165 1.00 73.84  ? 144 TYR A CE2 1 
ATOM   1131 C  CZ  . TYR A 1 144 ? 89.444  92.813  105.902 1.00 73.84  ? 144 TYR A CZ  1 
ATOM   1132 O  OH  . TYR A 1 144 ? 88.501  92.233  105.104 1.00 73.84  ? 144 TYR A OH  1 
ATOM   1133 N  N   . GLY A 1 145 ? 95.560  93.903  109.231 1.00 72.07  ? 145 GLY A N   1 
ATOM   1134 C  CA  . GLY A 1 145 ? 96.778  94.411  109.815 1.00 72.07  ? 145 GLY A CA  1 
ATOM   1135 C  C   . GLY A 1 145 ? 97.702  94.907  108.728 1.00 72.07  ? 145 GLY A C   1 
ATOM   1136 O  O   . GLY A 1 145 ? 97.437  94.747  107.538 1.00 72.07  ? 145 GLY A O   1 
ATOM   1137 N  N   . VAL A 1 146 ? 98.779  95.544  109.158 1.00 70.39  ? 146 VAL A N   1 
ATOM   1138 C  CA  . VAL A 1 146 ? 99.814  96.051  108.271 1.00 70.39  ? 146 VAL A CA  1 
ATOM   1139 C  C   . VAL A 1 146 ? 101.151 95.587  108.818 1.00 70.39  ? 146 VAL A C   1 
ATOM   1140 O  O   . VAL A 1 146 ? 101.414 95.721  110.014 1.00 70.39  ? 146 VAL A O   1 
ATOM   1141 C  CB  . VAL A 1 146 ? 99.775  97.591  108.164 1.00 70.39  ? 146 VAL A CB  1 
ATOM   1142 C  CG1 . VAL A 1 146 ? 100.942 98.117  107.365 1.00 70.39  ? 146 VAL A CG1 1 
ATOM   1143 C  CG2 . VAL A 1 146 ? 98.485  98.071  107.553 1.00 70.39  ? 146 VAL A CG2 1 
ATOM   1144 N  N   . SER A 1 147 ? 101.983 95.022  107.958 1.00 72.46  ? 147 SER A N   1 
ATOM   1145 C  CA  . SER A 1 147 ? 103.358 94.745  108.328 1.00 72.46  ? 147 SER A CA  1 
ATOM   1146 C  C   . SER A 1 147 ? 104.212 95.978  108.089 1.00 72.46  ? 147 SER A C   1 
ATOM   1147 O  O   . SER A 1 147 ? 104.042 96.684  107.098 1.00 72.46  ? 147 SER A O   1 
ATOM   1148 C  CB  . SER A 1 147 ? 103.915 93.573  107.534 1.00 72.46  ? 147 SER A CB  1 
ATOM   1149 O  OG  . SER A 1 147 ? 105.324 93.592  107.562 1.00 72.46  ? 147 SER A OG  1 
ATOM   1150 N  N   . LEU A 1 148 ? 105.152 96.226  108.999 1.00 70.91  ? 148 LEU A N   1 
ATOM   1151 C  CA  . LEU A 1 148 ? 106.055 97.357  108.843 1.00 70.91  ? 148 LEU A CA  1 
ATOM   1152 C  C   . LEU A 1 148 ? 107.098 97.136  107.759 1.00 70.91  ? 148 LEU A C   1 
ATOM   1153 O  O   . LEU A 1 148 ? 107.833 98.070  107.431 1.00 70.91  ? 148 LEU A O   1 
ATOM   1154 C  CB  . LEU A 1 148 ? 106.750 97.662  110.162 1.00 70.91  ? 148 LEU A CB  1 
ATOM   1155 C  CG  . LEU A 1 148 ? 105.950 98.362  111.251 1.00 70.91  ? 148 LEU A CG  1 
ATOM   1156 C  CD1 . LEU A 1 148 ? 106.876 98.826  112.344 1.00 70.91  ? 148 LEU A CD1 1 
ATOM   1157 C  CD2 . LEU A 1 148 ? 105.183 99.525  110.685 1.00 70.91  ? 148 LEU A CD2 1 
ATOM   1158 N  N   . TYR A 1 149 ? 107.182 95.927  107.204 1.00 74.82  ? 149 TYR A N   1 
ATOM   1159 C  CA  . TYR A 1 149 ? 107.991 95.676  106.022 1.00 74.82  ? 149 TYR A CA  1 
ATOM   1160 C  C   . TYR A 1 149 ? 107.443 96.399  104.797 1.00 74.82  ? 149 TYR A C   1 
ATOM   1161 O  O   . TYR A 1 149 ? 108.197 96.653  103.852 1.00 74.82  ? 149 TYR A O   1 
ATOM   1162 C  CB  . TYR A 1 149 ? 108.071 94.167  105.790 1.00 74.82  ? 149 TYR A CB  1 
ATOM   1163 C  CG  . TYR A 1 149 ? 108.687 93.756  104.486 1.00 74.82  ? 149 TYR A CG  1 
ATOM   1164 C  CD1 . TYR A 1 149 ? 110.049 93.852  104.285 1.00 74.82  ? 149 TYR A CD1 1 
ATOM   1165 C  CD2 . TYR A 1 149 ? 107.902 93.299  103.447 1.00 74.82  ? 149 TYR A CD2 1 
ATOM   1166 C  CE1 . TYR A 1 149 ? 110.613 93.490  103.092 1.00 74.82  ? 149 TYR A CE1 1 
ATOM   1167 C  CE2 . TYR A 1 149 ? 108.455 92.941  102.255 1.00 74.82  ? 149 TYR A CE2 1 
ATOM   1168 C  CZ  . TYR A 1 149 ? 109.810 93.034  102.081 1.00 74.82  ? 149 TYR A CZ  1 
ATOM   1169 O  OH  . TYR A 1 149 ? 110.368 92.668  100.885 1.00 74.82  ? 149 TYR A OH  1 
ATOM   1170 N  N   . SER A 1 150 ? 106.153 96.757  104.805 1.00 73.90  ? 150 SER A N   1 
ATOM   1171 C  CA  . SER A 1 150 ? 105.559 97.516  103.708 1.00 73.90  ? 150 SER A CA  1 
ATOM   1172 C  C   . SER A 1 150 ? 106.218 98.874  103.550 1.00 73.90  ? 150 SER A C   1 
ATOM   1173 O  O   . SER A 1 150 ? 106.317 99.399  102.439 1.00 73.90  ? 150 SER A O   1 
ATOM   1174 C  CB  . SER A 1 150 ? 104.066 97.697  103.948 1.00 73.90  ? 150 SER A CB  1 
ATOM   1175 O  OG  . SER A 1 150 ? 103.410 96.455  104.009 1.00 73.90  ? 150 SER A OG  1 
ATOM   1176 N  N   . TYR A 1 151 ? 106.683 99.452  104.646 1.00 73.99  ? 151 TYR A N   1 
ATOM   1177 C  CA  . TYR A 1 151 ? 107.472 100.674 104.607 1.00 73.99  ? 151 TYR A CA  1 
ATOM   1178 C  C   . TYR A 1 151 ? 108.955 100.339 104.732 1.00 73.99  ? 151 TYR A C   1 
ATOM   1179 O  O   . TYR A 1 151 ? 109.582 100.626 105.733 1.00 73.99  ? 151 TYR A O   1 
ATOM   1180 C  CB  . TYR A 1 151 ? 107.030 101.610 105.721 1.00 73.99  ? 151 TYR A CB  1 
ATOM   1181 C  CG  . TYR A 1 151 ? 105.538 101.720 105.900 1.00 73.99  ? 151 TYR A CG  1 
ATOM   1182 C  CD1 . TYR A 1 151 ? 104.714 102.049 104.836 1.00 73.99  ? 151 TYR A CD1 1 
ATOM   1183 C  CD2 . TYR A 1 151 ? 104.955 101.509 107.134 1.00 73.99  ? 151 TYR A CD2 1 
ATOM   1184 C  CE1 . TYR A 1 151 ? 103.355 102.158 104.998 1.00 73.99  ? 151 TYR A CE1 1 
ATOM   1185 C  CE2 . TYR A 1 151 ? 103.598 101.617 107.303 1.00 73.99  ? 151 TYR A CE2 1 
ATOM   1186 C  CZ  . TYR A 1 151 ? 102.805 101.943 106.232 1.00 73.99  ? 151 TYR A CZ  1 
ATOM   1187 O  OH  . TYR A 1 151 ? 101.451 102.053 106.397 1.00 73.99  ? 151 TYR A OH  1 
ATOM   1188 N  N   . MET A 1 152 ? 109.515 99.708  103.699 1.00 77.80  ? 152 MET A N   1 
ATOM   1189 C  CA  . MET A 1 152 ? 110.859 99.153  103.832 1.00 77.80  ? 152 MET A CA  1 
ATOM   1190 C  C   . MET A 1 152 ? 111.919 100.244 103.809 1.00 77.80  ? 152 MET A C   1 
ATOM   1191 O  O   . MET A 1 152 ? 112.681 100.402 104.768 1.00 77.80  ? 152 MET A O   1 
ATOM   1192 C  CB  . MET A 1 152 ? 111.126 98.128  102.738 1.00 77.80  ? 152 MET A CB  1 
ATOM   1193 C  CG  . MET A 1 152 ? 112.570 97.694  102.645 1.00 77.80  ? 152 MET A CG  1 
ATOM   1194 S  SD  . MET A 1 152 ? 112.862 96.565  101.285 1.00 77.80  ? 152 MET A SD  1 
ATOM   1195 C  CE  . MET A 1 152 ? 114.623 96.734  101.085 1.00 77.80  ? 152 MET A CE  1 
ATOM   1196 N  N   . SER A 1 153 ? 111.992 101.005 102.727 1.00 76.80  ? 153 SER A N   1 
ATOM   1197 C  CA  . SER A 1 153 ? 112.959 102.086 102.677 1.00 76.80  ? 153 SER A CA  1 
ATOM   1198 C  C   . SER A 1 153 ? 112.422 103.369 103.279 1.00 76.80  ? 153 SER A C   1 
ATOM   1199 O  O   . SER A 1 153 ? 113.202 104.287 103.543 1.00 76.80  ? 153 SER A O   1 
ATOM   1200 C  CB  . SER A 1 153 ? 113.401 102.337 101.238 1.00 76.80  ? 153 SER A CB  1 
ATOM   1201 O  OG  . SER A 1 153 ? 114.065 101.206 100.715 1.00 76.80  ? 153 SER A OG  1 
ATOM   1202 N  N   . ASP A 1 154 ? 111.113 103.443 103.509 1.00 78.32  ? 154 ASP A N   1 
ATOM   1203 C  CA  . ASP A 1 154 ? 110.526 104.631 104.111 1.00 78.32  ? 154 ASP A CA  1 
ATOM   1204 C  C   . ASP A 1 154 ? 110.833 104.705 105.596 1.00 78.32  ? 154 ASP A C   1 
ATOM   1205 O  O   . ASP A 1 154 ? 111.068 105.791 106.132 1.00 78.32  ? 154 ASP A O   1 
ATOM   1206 C  CB  . ASP A 1 154 ? 109.021 104.638 103.875 1.00 78.32  ? 154 ASP A CB  1 
ATOM   1207 C  CG  . ASP A 1 154 ? 108.657 105.069 102.478 1.00 78.32  ? 154 ASP A CG  1 
ATOM   1208 O  OD1 . ASP A 1 154 ? 109.468 105.766 101.844 1.00 78.32  ? 154 ASP A OD1 1 
ATOM   1209 O  OD2 . ASP A 1 154 ? 107.559 104.715 102.010 1.00 78.32  ? 154 ASP A OD2 1 
ATOM   1210 N  N   . TYR A 1 155 ? 110.834 103.562 106.275 1.00 77.78  ? 155 TYR A N   1 
ATOM   1211 C  CA  . TYR A 1 155 ? 111.130 103.523 107.699 1.00 77.78  ? 155 TYR A CA  1 
ATOM   1212 C  C   . TYR A 1 155 ? 112.602 103.814 107.932 1.00 77.78  ? 155 TYR A C   1 
ATOM   1213 O  O   . TYR A 1 155 ? 113.472 103.096 107.436 1.00 77.78  ? 155 TYR A O   1 
ATOM   1214 C  CB  . TYR A 1 155 ? 110.763 102.161 108.271 1.00 77.78  ? 155 TYR A CB  1 
ATOM   1215 C  CG  . TYR A 1 155 ? 110.791 102.078 109.767 1.00 77.78  ? 155 TYR A CG  1 
ATOM   1216 C  CD1 . TYR A 1 155 ? 111.924 101.642 110.431 1.00 77.78  ? 155 TYR A CD1 1 
ATOM   1217 C  CD2 . TYR A 1 155 ? 109.681 102.422 110.516 1.00 77.78  ? 155 TYR A CD2 1 
ATOM   1218 C  CE1 . TYR A 1 155 ? 111.959 101.567 111.791 1.00 77.78  ? 155 TYR A CE1 1 
ATOM   1219 C  CE2 . TYR A 1 155 ? 109.705 102.345 111.883 1.00 77.78  ? 155 TYR A CE2 1 
ATOM   1220 C  CZ  . TYR A 1 155 ? 110.849 101.918 112.513 1.00 77.78  ? 155 TYR A CZ  1 
ATOM   1221 O  OH  . TYR A 1 155 ? 110.890 101.835 113.882 1.00 77.78  ? 155 TYR A OH  1 
ATOM   1222 N  N   . GLY A 1 156 ? 112.878 104.860 108.696 1.00 77.10  ? 156 GLY A N   1 
ATOM   1223 C  CA  . GLY A 1 156 ? 114.228 105.282 108.966 1.00 77.10  ? 156 GLY A CA  1 
ATOM   1224 C  C   . GLY A 1 156 ? 114.700 106.432 108.116 1.00 77.10  ? 156 GLY A C   1 
ATOM   1225 O  O   . GLY A 1 156 ? 115.684 107.082 108.477 1.00 77.10  ? 156 GLY A O   1 
ATOM   1226 N  N   . THR A 1 157 ? 114.038 106.701 106.997 1.00 75.83  ? 157 THR A N   1 
ATOM   1227 C  CA  . THR A 1 157 ? 114.361 107.839 106.154 1.00 75.83  ? 157 THR A CA  1 
ATOM   1228 C  C   . THR A 1 157 ? 113.280 108.906 106.178 1.00 75.83  ? 157 THR A C   1 
ATOM   1229 O  O   . THR A 1 157 ? 113.583 110.080 106.381 1.00 75.83  ? 157 THR A O   1 
ATOM   1230 C  CB  . THR A 1 157 ? 114.607 107.383 104.712 1.00 75.83  ? 157 THR A CB  1 
ATOM   1231 O  OG1 . THR A 1 157 ? 113.435 106.743 104.209 1.00 75.83  ? 157 THR A OG1 1 
ATOM   1232 C  CG2 . THR A 1 157 ? 115.746 106.410 104.659 1.00 75.83  ? 157 THR A CG2 1 
ATOM   1233 N  N   . VAL A 1 158 ? 112.020 108.530 105.973 1.00 75.62  ? 158 VAL A N   1 
ATOM   1234 C  CA  . VAL A 1 158 ? 110.909 109.474 106.019 1.00 75.62  ? 158 VAL A CA  1 
ATOM   1235 C  C   . VAL A 1 158 ? 109.923 109.164 107.127 1.00 75.62  ? 158 VAL A C   1 
ATOM   1236 O  O   . VAL A 1 158 ? 108.951 109.908 107.294 1.00 75.62  ? 158 VAL A O   1 
ATOM   1237 C  CB  . VAL A 1 158 ? 110.162 109.545 104.671 1.00 75.62  ? 158 VAL A CB  1 
ATOM   1238 C  CG1 . VAL A 1 158 ? 111.114 109.715 103.544 1.00 75.62  ? 158 VAL A CG1 1 
ATOM   1239 C  CG2 . VAL A 1 158 ? 109.335 108.309 104.453 1.00 75.62  ? 158 VAL A CG2 1 
ATOM   1240 N  N   . MET A 1 159 ? 110.140 108.105 107.895 1.00 79.30  ? 159 MET A N   1 
ATOM   1241 C  CA  . MET A 1 159 ? 109.114 107.598 108.785 1.00 79.30  ? 159 MET A CA  1 
ATOM   1242 C  C   . MET A 1 159 ? 109.757 107.012 110.029 1.00 79.30  ? 159 MET A C   1 
ATOM   1243 O  O   . MET A 1 159 ? 110.816 106.390 109.961 1.00 79.30  ? 159 MET A O   1 
ATOM   1244 C  CB  . MET A 1 159 ? 108.275 106.538 108.075 1.00 79.30  ? 159 MET A CB  1 
ATOM   1245 C  CG  . MET A 1 159 ? 106.918 106.308 108.659 1.00 79.30  ? 159 MET A CG  1 
ATOM   1246 S  SD  . MET A 1 159 ? 106.054 105.007 107.777 1.00 79.30  ? 159 MET A SD  1 
ATOM   1247 C  CE  . MET A 1 159 ? 106.130 105.642 106.116 1.00 79.30  ? 159 MET A CE  1 
ATOM   1248 N  N   . ASP A 1 160 ? 109.103 107.216 111.164 1.00 80.99  ? 160 ASP A N   1 
ATOM   1249 C  CA  . ASP A 1 160 ? 109.468 106.574 112.414 1.00 80.99  ? 160 ASP A CA  1 
ATOM   1250 C  C   . ASP A 1 160 ? 108.311 105.701 112.872 1.00 80.99  ? 160 ASP A C   1 
ATOM   1251 O  O   . ASP A 1 160 ? 107.370 105.445 112.122 1.00 80.99  ? 160 ASP A O   1 
ATOM   1252 C  CB  . ASP A 1 160 ? 109.846 107.592 113.490 1.00 80.99  ? 160 ASP A CB  1 
ATOM   1253 C  CG  . ASP A 1 160 ? 108.816 108.672 113.656 1.00 80.99  ? 160 ASP A CG  1 
ATOM   1254 O  OD1 . ASP A 1 160 ? 108.016 108.863 112.731 1.00 80.99  ? 160 ASP A OD1 1 
ATOM   1255 O  OD2 . ASP A 1 160 ? 108.798 109.327 114.715 1.00 80.99  ? 160 ASP A OD2 1 
ATOM   1256 N  N   . LEU A 1 161 ? 108.403 105.224 114.113 1.00 77.01  ? 161 LEU A N   1 
ATOM   1257 C  CA  . LEU A 1 161 ? 107.453 104.230 114.601 1.00 77.01  ? 161 LEU A CA  1 
ATOM   1258 C  C   . LEU A 1 161 ? 106.068 104.824 114.819 1.00 77.01  ? 161 LEU A C   1 
ATOM   1259 O  O   . LEU A 1 161 ? 105.060 104.177 114.524 1.00 77.01  ? 161 LEU A O   1 
ATOM   1260 C  CB  . LEU A 1 161 ? 107.973 103.605 115.891 1.00 77.01  ? 161 LEU A CB  1 
ATOM   1261 C  CG  . LEU A 1 161 ? 107.136 102.472 116.471 1.00 77.01  ? 161 LEU A CG  1 
ATOM   1262 C  CD1 . LEU A 1 161 ? 107.039 101.343 115.480 1.00 77.01  ? 161 LEU A CD1 1 
ATOM   1263 C  CD2 . LEU A 1 161 ? 107.722 101.990 117.771 1.00 77.01  ? 161 LEU A CD2 1 
ATOM   1264 N  N   . GLU A 1 162 ? 105.993 106.053 115.325 1.00 79.00  ? 162 GLU A N   1 
ATOM   1265 C  CA  . GLU A 1 162 ? 104.690 106.639 115.614 1.00 79.00  ? 162 GLU A CA  1 
ATOM   1266 C  C   . GLU A 1 162 ? 103.978 107.071 114.342 1.00 79.00  ? 162 GLU A C   1 
ATOM   1267 O  O   . GLU A 1 162 ? 102.748 106.995 114.261 1.00 79.00  ? 162 GLU A O   1 
ATOM   1268 C  CB  . GLU A 1 162 ? 104.836 107.822 116.562 1.00 79.00  ? 162 GLU A CB  1 
ATOM   1269 C  CG  . GLU A 1 162 ? 103.522 108.261 117.166 1.00 79.00  ? 162 GLU A CG  1 
ATOM   1270 C  CD  . GLU A 1 162 ? 103.666 109.436 118.094 1.00 79.00  ? 162 GLU A CD  1 
ATOM   1271 O  OE1 . GLU A 1 162 ? 104.763 110.027 118.133 1.00 79.00  ? 162 GLU A OE1 1 
ATOM   1272 O  OE2 . GLU A 1 162 ? 102.683 109.772 118.784 1.00 79.00  ? 162 GLU A OE2 1 
ATOM   1273 N  N   . THR A 1 163 ? 104.730 107.533 113.343 1.00 77.36  ? 163 THR A N   1 
ATOM   1274 C  CA  . THR A 1 163 ? 104.127 107.893 112.065 1.00 77.36  ? 163 THR A CA  1 
ATOM   1275 C  C   . THR A 1 163 ? 103.604 106.659 111.351 1.00 77.36  ? 163 THR A C   1 
ATOM   1276 O  O   . THR A 1 163 ? 102.546 106.699 110.717 1.00 77.36  ? 163 THR A O   1 
ATOM   1277 C  CB  . THR A 1 163 ? 105.149 108.617 111.195 1.00 77.36  ? 163 THR A CB  1 
ATOM   1278 O  OG1 . THR A 1 163 ? 105.702 109.708 111.933 1.00 77.36  ? 163 THR A OG1 1 
ATOM   1279 C  CG2 . THR A 1 163 ? 104.511 109.168 109.948 1.00 77.36  ? 163 THR A CG2 1 
ATOM   1280 N  N   . ALA A 1 164 ? 104.324 105.547 111.465 1.00 72.76  ? 164 ALA A N   1 
ATOM   1281 C  CA  . ALA A 1 164 ? 103.862 104.302 110.872 1.00 72.76  ? 164 ALA A CA  1 
ATOM   1282 C  C   . ALA A 1 164 ? 102.642 103.772 111.603 1.00 72.76  ? 164 ALA A C   1 
ATOM   1283 O  O   . ALA A 1 164 ? 101.713 103.261 110.976 1.00 72.76  ? 164 ALA A O   1 
ATOM   1284 C  CB  . ALA A 1 164 ? 104.985 103.271 110.883 1.00 72.76  ? 164 ALA A CB  1 
ATOM   1285 N  N   . MET A 1 165 ? 102.614 103.912 112.926 1.00 74.28  ? 165 MET A N   1 
ATOM   1286 C  CA  . MET A 1 165 ? 101.490 103.411 113.705 1.00 74.28  ? 165 MET A CA  1 
ATOM   1287 C  C   . MET A 1 165 ? 100.250 104.267 113.516 1.00 74.28  ? 165 MET A C   1 
ATOM   1288 O  O   . MET A 1 165 ? 99.127  103.766 113.605 1.00 74.28  ? 165 MET A O   1 
ATOM   1289 C  CB  . MET A 1 165 ? 101.865 103.359 115.177 1.00 74.28  ? 165 MET A CB  1 
ATOM   1290 C  CG  . MET A 1 165 ? 102.426 102.046 115.618 1.00 74.28  ? 165 MET A CG  1 
ATOM   1291 S  SD  . MET A 1 165 ? 103.149 102.197 117.242 1.00 74.28  ? 165 MET A SD  1 
ATOM   1292 C  CE  . MET A 1 165 ? 102.858 100.575 117.888 1.00 74.28  ? 165 MET A CE  1 
ATOM   1293 N  N   . ALA A 1 166 ? 100.432 105.564 113.276 1.00 72.78  ? 166 ALA A N   1 
ATOM   1294 C  CA  . ALA A 1 166 ? 99.292  106.441 113.044 1.00 72.78  ? 166 ALA A CA  1 
ATOM   1295 C  C   . ALA A 1 166 ? 98.636  106.138 111.710 1.00 72.78  ? 166 ALA A C   1 
ATOM   1296 O  O   . ALA A 1 166 ? 97.419  106.277 111.557 1.00 72.78  ? 166 ALA A O   1 
ATOM   1297 C  CB  . ALA A 1 166 ? 99.735  107.897 113.098 1.00 72.78  ? 166 ALA A CB  1 
ATOM   1298 N  N   . SER A 1 167 ? 99.430  105.718 110.732 1.00 71.19  ? 167 SER A N   1 
ATOM   1299 C  CA  . SER A 1 167 ? 98.881  105.397 109.426 1.00 71.19  ? 167 SER A CA  1 
ATOM   1300 C  C   . SER A 1 167 ? 98.148  104.068 109.449 1.00 71.19  ? 167 SER A C   1 
ATOM   1301 O  O   . SER A 1 167 ? 97.181  103.884 108.713 1.00 71.19  ? 167 SER A O   1 
ATOM   1302 C  CB  . SER A 1 167 ? 99.991  105.376 108.385 1.00 71.19  ? 167 SER A CB  1 
ATOM   1303 O  OG  . SER A 1 167 ? 100.863 104.295 108.621 1.00 71.19  ? 167 SER A OG  1 
ATOM   1304 N  N   . ILE A 1 168 ? 98.587  103.134 110.291 1.00 71.04  ? 168 ILE A N   1 
ATOM   1305 C  CA  . ILE A 1 168 ? 97.917  101.841 110.389 1.00 71.04  ? 168 ILE A CA  1 
ATOM   1306 C  C   . ILE A 1 168 ? 96.558  101.993 111.059 1.00 71.04  ? 168 ILE A C   1 
ATOM   1307 O  O   . ILE A 1 168 ? 95.569  101.386 110.636 1.00 71.04  ? 168 ILE A O   1 
ATOM   1308 C  CB  . ILE A 1 168 ? 98.820  100.843 111.135 1.00 71.04  ? 168 ILE A CB  1 
ATOM   1309 C  CG1 . ILE A 1 168 ? 100.075 100.568 110.321 1.00 71.04  ? 168 ILE A CG1 1 
ATOM   1310 C  CG2 . ILE A 1 168 ? 98.115  99.539  111.394 1.00 71.04  ? 168 ILE A CG2 1 
ATOM   1311 C  CD1 . ILE A 1 168 ? 101.087 99.735  111.039 1.00 71.04  ? 168 ILE A CD1 1 
ATOM   1312 N  N   . ALA A 1 169 ? 96.477  102.836 112.085 1.00 72.23  ? 169 ALA A N   1 
ATOM   1313 C  CA  . ALA A 1 169 ? 95.218  103.025 112.793 1.00 72.23  ? 169 ALA A CA  1 
ATOM   1314 C  C   . ALA A 1 169 ? 94.227  103.837 111.973 1.00 72.23  ? 169 ALA A C   1 
ATOM   1315 O  O   . ALA A 1 169 ? 93.021  103.791 112.229 1.00 72.23  ? 169 ALA A O   1 
ATOM   1316 C  CB  . ALA A 1 169 ? 95.475  103.698 114.133 1.00 72.23  ? 169 ALA A CB  1 
ATOM   1317 N  N   . ASP A 1 170 ? 94.711  104.591 110.987 1.00 74.21  ? 170 ASP A N   1 
ATOM   1318 C  CA  . ASP A 1 170 ? 93.804  105.356 110.144 1.00 74.21  ? 170 ASP A CA  1 
ATOM   1319 C  C   . ASP A 1 170 ? 93.121  104.470 109.115 1.00 74.21  ? 170 ASP A C   1 
ATOM   1320 O  O   . ASP A 1 170 ? 92.037  104.801 108.629 1.00 74.21  ? 170 ASP A O   1 
ATOM   1321 C  CB  . ASP A 1 170 ? 94.549  106.489 109.453 1.00 74.21  ? 170 ASP A CB  1 
ATOM   1322 C  CG  . ASP A 1 170 ? 93.618  107.568 108.957 1.00 74.21  ? 170 ASP A CG  1 
ATOM   1323 O  OD1 . ASP A 1 170 ? 93.016  108.263 109.798 1.00 74.21  ? 170 ASP A OD1 1 
ATOM   1324 O  OD2 . ASP A 1 170 ? 93.475  107.723 107.730 1.00 74.21  ? 170 ASP A OD2 1 
ATOM   1325 N  N   . LEU A 1 171 ? 93.735  103.339 108.768 1.00 73.86  ? 171 LEU A N   1 
ATOM   1326 C  CA  . LEU A 1 171 ? 93.072  102.386 107.887 1.00 73.86  ? 171 LEU A CA  1 
ATOM   1327 C  C   . LEU A 1 171 ? 91.928  101.676 108.587 1.00 73.86  ? 171 LEU A C   1 
ATOM   1328 O  O   . LEU A 1 171 ? 91.053  101.108 107.929 1.00 73.86  ? 171 LEU A O   1 
ATOM   1329 C  CB  . LEU A 1 171 ? 94.054  101.338 107.371 1.00 73.86  ? 171 LEU A CB  1 
ATOM   1330 C  CG  . LEU A 1 171 ? 94.782  101.550 106.054 1.00 73.86  ? 171 LEU A CG  1 
ATOM   1331 C  CD1 . LEU A 1 171 ? 93.757  101.816 104.989 1.00 73.86  ? 171 LEU A CD1 1 
ATOM   1332 C  CD2 . LEU A 1 171 ? 95.770  102.646 106.105 1.00 73.86  ? 171 LEU A CD2 1 
ATOM   1333 N  N   . GLY A 1 172 ? 91.923  101.677 109.910 1.00 72.62  ? 172 GLY A N   1 
ATOM   1334 C  CA  . GLY A 1 172 ? 91.031  100.833 110.660 1.00 72.62  ? 172 GLY A CA  1 
ATOM   1335 C  C   . GLY A 1 172 ? 91.588  99.466  110.942 1.00 72.62  ? 172 GLY A C   1 
ATOM   1336 O  O   . GLY A 1 172 ? 90.854  98.609  111.439 1.00 72.62  ? 172 GLY A O   1 
ATOM   1337 N  N   . ALA A 1 173 ? 92.853  99.231  110.623 1.00 72.60  ? 173 ALA A N   1 
ATOM   1338 C  CA  . ALA A 1 173 ? 93.492  97.968  110.932 1.00 72.60  ? 173 ALA A CA  1 
ATOM   1339 C  C   . ALA A 1 173 ? 93.747  97.869  112.425 1.00 72.60  ? 173 ALA A C   1 
ATOM   1340 O  O   . ALA A 1 173 ? 93.922  98.876  113.110 1.00 72.60  ? 173 ALA A O   1 
ATOM   1341 C  CB  . ALA A 1 173 ? 94.801  97.837  110.163 1.00 72.60  ? 173 ALA A CB  1 
ATOM   1342 N  N   . THR A 1 174 ? 93.759  96.642  112.934 1.00 73.19  ? 174 THR A N   1 
ATOM   1343 C  CA  . THR A 1 174 ? 93.922  96.417  114.361 1.00 73.19  ? 174 THR A CA  1 
ATOM   1344 C  C   . THR A 1 174 ? 95.216  95.697  114.700 1.00 73.19  ? 174 THR A C   1 
ATOM   1345 O  O   . THR A 1 174 ? 95.573  95.622  115.875 1.00 73.19  ? 174 THR A O   1 
ATOM   1346 C  CB  . THR A 1 174 ? 92.735  95.632  114.914 1.00 73.19  ? 174 THR A CB  1 
ATOM   1347 O  OG1 . THR A 1 174 ? 92.542  94.450  114.136 1.00 73.19  ? 174 THR A OG1 1 
ATOM   1348 C  CG2 . THR A 1 174 ? 91.485  96.466  114.848 1.00 73.19  ? 174 THR A CG2 1 
ATOM   1349 N  N   . GLY A 1 175 ? 95.930  95.181  113.716 1.00 70.51  ? 175 GLY A N   1 
ATOM   1350 C  CA  . GLY A 1 175 ? 97.162  94.461  113.971 1.00 70.51  ? 175 GLY A CA  1 
ATOM   1351 C  C   . GLY A 1 175 ? 98.351  95.163  113.363 1.00 70.51  ? 175 GLY A C   1 
ATOM   1352 O  O   . GLY A 1 175 ? 98.229  95.888  112.383 1.00 70.51  ? 175 GLY A O   1 
ATOM   1353 N  N   . ILE A 1 176 ? 99.512  94.946  113.967 1.00 69.79  ? 176 ILE A N   1 
ATOM   1354 C  CA  . ILE A 1 176 ? 100.772 95.451  113.446 1.00 69.79  ? 176 ILE A CA  1 
ATOM   1355 C  C   . ILE A 1 176 ? 101.792 94.322  113.497 1.00 69.79  ? 176 ILE A C   1 
ATOM   1356 O  O   . ILE A 1 176 ? 101.884 93.598  114.493 1.00 69.79  ? 176 ILE A O   1 
ATOM   1357 C  CB  . ILE A 1 176 ? 101.242 96.708  114.208 1.00 69.79  ? 176 ILE A CB  1 
ATOM   1358 C  CG1 . ILE A 1 176 ? 102.607 97.180  113.717 1.00 69.79  ? 176 ILE A CG1 1 
ATOM   1359 C  CG2 . ILE A 1 176 ? 101.222 96.508  115.713 1.00 69.79  ? 176 ILE A CG2 1 
ATOM   1360 C  CD1 . ILE A 1 176 ? 103.003 98.522  114.230 1.00 69.79  ? 176 ILE A CD1 1 
ATOM   1361 N  N   . GLU A 1 177 ? 102.508 94.131  112.399 1.00 73.85  ? 177 GLU A N   1 
ATOM   1362 C  CA  . GLU A 1 177 ? 103.542 93.121  112.284 1.00 73.85  ? 177 GLU A CA  1 
ATOM   1363 C  C   . GLU A 1 177 ? 104.873 93.814  112.059 1.00 73.85  ? 177 GLU A C   1 
ATOM   1364 O  O   . GLU A 1 177 ? 104.969 94.724  111.237 1.00 73.85  ? 177 GLU A O   1 
ATOM   1365 C  CB  . GLU A 1 177 ? 103.238 92.164  111.137 1.00 73.85  ? 177 GLU A CB  1 
ATOM   1366 C  CG  . GLU A 1 177 ? 104.442 91.451  110.580 1.00 73.85  ? 177 GLU A CG  1 
ATOM   1367 C  CD  . GLU A 1 177 ? 104.090 90.476  109.490 1.00 73.85  ? 177 GLU A CD  1 
ATOM   1368 O  OE1 . GLU A 1 177 ? 102.959 90.548  108.976 1.00 73.85  ? 177 GLU A OE1 1 
ATOM   1369 O  OE2 . GLU A 1 177 ? 104.945 89.637  109.146 1.00 73.85  ? 177 GLU A OE2 1 
ATOM   1370 N  N   . ILE A 1 178 ? 105.893 93.420  112.818 1.00 71.68  ? 178 ILE A N   1 
ATOM   1371 C  CA  . ILE A 1 178 ? 107.222 93.986  112.652 1.00 71.68  ? 178 ILE A CA  1 
ATOM   1372 C  C   . ILE A 1 178 ? 108.206 92.876  112.322 1.00 71.68  ? 178 ILE A C   1 
ATOM   1373 O  O   . ILE A 1 178 ? 107.927 91.692  112.496 1.00 71.68  ? 178 ILE A O   1 
ATOM   1374 C  CB  . ILE A 1 178 ? 107.704 94.766  113.897 1.00 71.68  ? 178 ILE A CB  1 
ATOM   1375 C  CG1 . ILE A 1 178 ? 108.233 93.817  114.968 1.00 71.68  ? 178 ILE A CG1 1 
ATOM   1376 C  CG2 . ILE A 1 178 ? 106.608 95.644  114.460 1.00 71.68  ? 178 ILE A CG2 1 
ATOM   1377 C  CD1 . ILE A 1 178 ? 108.852 94.523  116.136 1.00 71.68  ? 178 ILE A CD1 1 
ATOM   1378 N  N   . LEU A 1 179 ? 109.357 93.277  111.803 1.00 72.78  ? 179 LEU A N   1 
ATOM   1379 C  CA  . LEU A 1 179 ? 110.540 92.435  111.789 1.00 72.78  ? 179 LEU A CA  1 
ATOM   1380 C  C   . LEU A 1 179 ? 111.397 92.847  112.970 1.00 72.78  ? 179 LEU A C   1 
ATOM   1381 O  O   . LEU A 1 179 ? 111.795 94.010  113.067 1.00 72.78  ? 179 LEU A O   1 
ATOM   1382 C  CB  . LEU A 1 179 ? 111.322 92.592  110.489 1.00 72.78  ? 179 LEU A CB  1 
ATOM   1383 C  CG  . LEU A 1 179 ? 110.533 92.576  109.187 1.00 72.78  ? 179 LEU A CG  1 
ATOM   1384 C  CD1 . LEU A 1 179 ? 111.333 93.242  108.098 1.00 72.78  ? 179 LEU A CD1 1 
ATOM   1385 C  CD2 . LEU A 1 179 ? 110.193 91.163  108.802 1.00 72.78  ? 179 LEU A CD2 1 
ATOM   1386 N  N   . GLY A 1 180 ? 111.665 91.901  113.868 1.00 73.24  ? 180 GLY A N   1 
ATOM   1387 C  CA  . GLY A 1 180 ? 112.261 92.255  115.146 1.00 73.24  ? 180 GLY A CA  1 
ATOM   1388 C  C   . GLY A 1 180 ? 113.695 92.719  115.020 1.00 73.24  ? 180 GLY A C   1 
ATOM   1389 O  O   . GLY A 1 180 ? 114.152 93.566  115.784 1.00 73.24  ? 180 GLY A O   1 
ATOM   1390 N  N   . GLU A 1 181 ? 114.405 92.207  114.025 1.00 75.95  ? 181 GLU A N   1 
ATOM   1391 C  CA  . GLU A 1 181 ? 115.803 92.544  113.825 1.00 75.95  ? 181 GLU A CA  1 
ATOM   1392 C  C   . GLU A 1 181 ? 115.960 93.813  112.992 1.00 75.95  ? 181 GLU A C   1 
ATOM   1393 O  O   . GLU A 1 181 ? 117.080 94.194  112.651 1.00 75.95  ? 181 GLU A O   1 
ATOM   1394 C  CB  . GLU A 1 181 ? 116.483 91.317  113.207 1.00 75.95  ? 181 GLU A CB  1 
ATOM   1395 C  CG  . GLU A 1 181 ? 117.971 91.218  113.356 1.00 75.95  ? 181 GLU A CG  1 
ATOM   1396 C  CD  . GLU A 1 181 ? 118.502 89.865  112.987 1.00 75.95  ? 181 GLU A CD  1 
ATOM   1397 O  OE1 . GLU A 1 181 ? 117.691 88.985  112.644 1.00 75.95  ? 181 GLU A OE1 1 
ATOM   1398 O  OE2 . GLU A 1 181 ? 119.731 89.666  113.055 1.00 75.95  ? 181 GLU A OE2 1 
ATOM   1399 N  N   . ALA A 1 182 ? 114.859 94.491  112.682 1.00 72.52  ? 182 ALA A N   1 
ATOM   1400 C  CA  . ALA A 1 182 ? 114.849 95.732  111.925 1.00 72.52  ? 182 ALA A CA  1 
ATOM   1401 C  C   . ALA A 1 182 ? 114.197 96.882  112.670 1.00 72.52  ? 182 ALA A C   1 
ATOM   1402 O  O   . ALA A 1 182 ? 114.649 98.021  112.553 1.00 72.52  ? 182 ALA A O   1 
ATOM   1403 C  CB  . ALA A 1 182 ? 114.114 95.532  110.603 1.00 72.52  ? 182 ALA A CB  1 
ATOM   1404 N  N   . HIS A 1 183 ? 113.139 96.612  113.428 1.00 71.30  ? 183 HIS A N   1 
ATOM   1405 C  CA  . HIS A 1 183 ? 112.312 97.665  113.990 1.00 71.30  ? 183 HIS A CA  1 
ATOM   1406 C  C   . HIS A 1 183 ? 112.434 97.800  115.496 1.00 71.30  ? 183 HIS A C   1 
ATOM   1407 O  O   . HIS A 1 183 ? 111.882 98.748  116.056 1.00 71.30  ? 183 HIS A O   1 
ATOM   1408 C  CB  . HIS A 1 183 ? 110.851 97.431  113.616 1.00 71.30  ? 183 HIS A CB  1 
ATOM   1409 C  CG  . HIS A 1 183 ? 110.621 97.358  112.143 1.00 71.30  ? 183 HIS A CG  1 
ATOM   1410 N  ND1 . HIS A 1 183 ? 110.157 96.224  111.520 1.00 71.30  ? 183 HIS A ND1 1 
ATOM   1411 C  CD2 . HIS A 1 183 ? 110.805 98.275  111.169 1.00 71.30  ? 183 HIS A CD2 1 
ATOM   1412 C  CE1 . HIS A 1 183 ? 110.061 96.447  110.224 1.00 71.30  ? 183 HIS A CE1 1 
ATOM   1413 N  NE2 . HIS A 1 183 ? 110.447 97.685  109.985 1.00 71.30  ? 183 HIS A NE2 1 
ATOM   1414 N  N   . VAL A 1 184 ? 113.128 96.890  116.163 1.00 71.65  ? 184 VAL A N   1 
ATOM   1415 C  CA  . VAL A 1 184 ? 113.421 97.012  117.587 1.00 71.65  ? 184 VAL A CA  1 
ATOM   1416 C  C   . VAL A 1 184 ? 114.802 97.636  117.715 1.00 71.65  ? 184 VAL A C   1 
ATOM   1417 O  O   . VAL A 1 184 ? 115.791 97.007  117.311 1.00 71.65  ? 184 VAL A O   1 
ATOM   1418 C  CB  . VAL A 1 184 ? 113.358 95.656  118.296 1.00 71.65  ? 184 VAL A CB  1 
ATOM   1419 C  CG1 . VAL A 1 184 ? 113.775 95.803  119.734 1.00 71.65  ? 184 VAL A CG1 1 
ATOM   1420 C  CG2 . VAL A 1 184 ? 111.974 95.094  118.210 1.00 71.65  ? 184 VAL A CG2 1 
ATOM   1421 N  N   . PRO A 1 185 ? 114.923 98.855  118.227 1.00 72.77  ? 185 PRO A N   1 
ATOM   1422 C  CA  . PRO A 1 185 ? 116.243 99.465  118.372 1.00 72.77  ? 185 PRO A CA  1 
ATOM   1423 C  C   . PRO A 1 185 ? 117.026 98.823  119.499 1.00 72.77  ? 185 PRO A C   1 
ATOM   1424 O  O   . PRO A 1 185 ? 116.456 98.393  120.503 1.00 72.77  ? 185 PRO A O   1 
ATOM   1425 C  CB  . PRO A 1 185 ? 115.922 100.928 118.678 1.00 72.77  ? 185 PRO A CB  1 
ATOM   1426 C  CG  . PRO A 1 185 ? 114.579 100.896 119.240 1.00 72.77  ? 185 PRO A CG  1 
ATOM   1427 C  CD  . PRO A 1 185 ? 113.852 99.801  118.552 1.00 72.77  ? 185 PRO A CD  1 
ATOM   1428 N  N   . ASN A 1 186 ? 118.349 98.786  119.312 1.00 74.32  ? 186 ASN A N   1 
ATOM   1429 C  CA  . ASN A 1 186 ? 119.291 98.067  120.170 1.00 74.32  ? 186 ASN A CA  1 
ATOM   1430 C  C   . ASN A 1 186 ? 118.894 96.602  120.306 1.00 74.32  ? 186 ASN A C   1 
ATOM   1431 O  O   . ASN A 1 186 ? 118.774 96.072  121.404 1.00 74.32  ? 186 ASN A O   1 
ATOM   1432 C  CB  . ASN A 1 186 ? 119.436 98.734  121.540 1.00 74.32  ? 186 ASN A CB  1 
ATOM   1433 C  CG  . ASN A 1 186 ? 120.695 98.327  122.252 1.00 74.32  ? 186 ASN A CG  1 
ATOM   1434 O  OD1 . ASN A 1 186 ? 121.796 98.538  121.755 1.00 74.32  ? 186 ASN A OD1 1 
ATOM   1435 N  ND2 . ASN A 1 186 ? 120.542 97.729  123.421 1.00 74.32  ? 186 ASN A ND2 1 
ATOM   1436 N  N   . TYR A 1 187 ? 118.665 95.963  119.171 1.00 74.52  ? 187 TYR A N   1 
ATOM   1437 C  CA  . TYR A 1 187 ? 118.337 94.549  119.142 1.00 74.52  ? 187 TYR A CA  1 
ATOM   1438 C  C   . TYR A 1 187 ? 119.514 93.735  119.675 1.00 74.52  ? 187 TYR A C   1 
ATOM   1439 O  O   . TYR A 1 187 ? 120.669 94.050  119.375 1.00 74.52  ? 187 TYR A O   1 
ATOM   1440 C  CB  . TYR A 1 187 ? 117.998 94.144  117.705 1.00 74.52  ? 187 TYR A CB  1 
ATOM   1441 C  CG  . TYR A 1 187 ? 117.648 92.700  117.492 1.00 74.52  ? 187 TYR A CG  1 
ATOM   1442 C  CD1 . TYR A 1 187 ? 116.354 92.259  117.665 1.00 74.52  ? 187 TYR A CD1 1 
ATOM   1443 C  CD2 . TYR A 1 187 ? 118.608 91.781  117.105 1.00 74.52  ? 187 TYR A CD2 1 
ATOM   1444 C  CE1 . TYR A 1 187 ? 116.026 90.949  117.471 1.00 74.52  ? 187 TYR A CE1 1 
ATOM   1445 C  CE2 . TYR A 1 187 ? 118.290 90.469  116.918 1.00 74.52  ? 187 TYR A CE2 1 
ATOM   1446 C  CZ  . TYR A 1 187 ? 116.998 90.061  117.099 1.00 74.52  ? 187 TYR A CZ  1 
ATOM   1447 O  OH  . TYR A 1 187 ? 116.668 88.749  116.904 1.00 74.52  ? 187 TYR A OH  1 
ATOM   1448 N  N   . PRO A 1 188 ? 119.269 92.692  120.477 1.00 75.21  ? 188 PRO A N   1 
ATOM   1449 C  CA  . PRO A 1 188 ? 117.988 92.171  120.942 1.00 75.21  ? 188 PRO A CA  1 
ATOM   1450 C  C   . PRO A 1 188 ? 117.594 92.620  122.335 1.00 75.21  ? 188 PRO A C   1 
ATOM   1451 O  O   . PRO A 1 188 ? 116.726 92.005  122.936 1.00 75.21  ? 188 PRO A O   1 
ATOM   1452 C  CB  . PRO A 1 188 ? 118.225 90.671  120.926 1.00 75.21  ? 188 PRO A CB  1 
ATOM   1453 C  CG  . PRO A 1 188 ? 119.638 90.551  121.327 1.00 75.21  ? 188 PRO A CG  1 
ATOM   1454 C  CD  . PRO A 1 188 ? 120.361 91.772  120.822 1.00 75.21  ? 188 PRO A CD  1 
ATOM   1455 N  N   . ASN A 1 189 ? 118.220 93.675  122.849 1.00 78.13  ? 189 ASN A N   1 
ATOM   1456 C  CA  . ASN A 1 189 ? 117.961 94.171  124.198 1.00 78.13  ? 189 ASN A CA  1 
ATOM   1457 C  C   . ASN A 1 189 ? 117.508 95.621  124.121 1.00 78.13  ? 189 ASN A C   1 
ATOM   1458 O  O   . ASN A 1 189 ? 118.325 96.538  124.291 1.00 78.13  ? 189 ASN A O   1 
ATOM   1459 C  CB  . ASN A 1 189 ? 119.202 94.053  125.074 1.00 78.13  ? 189 ASN A CB  1 
ATOM   1460 C  CG  . ASN A 1 189 ? 119.704 92.641  125.176 1.00 78.13  ? 189 ASN A CG  1 
ATOM   1461 O  OD1 . ASN A 1 189 ? 119.126 91.820  125.879 1.00 78.13  ? 189 ASN A OD1 1 
ATOM   1462 N  ND2 . ASN A 1 189 ? 120.792 92.348  124.482 1.00 78.13  ? 189 ASN A ND2 1 
ATOM   1463 N  N   . PRO A 1 190 ? 116.236 95.878  123.837 1.00 76.90  ? 190 PRO A N   1 
ATOM   1464 C  CA  . PRO A 1 190 ? 115.755 97.256  123.859 1.00 76.90  ? 190 PRO A CA  1 
ATOM   1465 C  C   . PRO A 1 190 ? 115.682 97.772  125.283 1.00 76.90  ? 190 PRO A C   1 
ATOM   1466 O  O   . PRO A 1 190 ? 115.551 97.008  126.241 1.00 76.90  ? 190 PRO A O   1 
ATOM   1467 C  CB  . PRO A 1 190 ? 114.367 97.157  123.228 1.00 76.90  ? 190 PRO A CB  1 
ATOM   1468 C  CG  . PRO A 1 190 ? 113.950 95.780  123.485 1.00 76.90  ? 190 PRO A CG  1 
ATOM   1469 C  CD  . PRO A 1 190 ? 115.176 94.946  123.425 1.00 76.90  ? 190 PRO A CD  1 
ATOM   1470 N  N   . SER A 1 191 ? 115.795 99.087  125.414 1.00 80.42  ? 191 SER A N   1 
ATOM   1471 C  CA  . SER A 1 191 ? 115.773 99.700  126.728 1.00 80.42  ? 191 SER A CA  1 
ATOM   1472 C  C   . SER A 1 191 ? 114.375 99.629  127.324 1.00 80.42  ? 191 SER A C   1 
ATOM   1473 O  O   . SER A 1 191 ? 113.383 99.440  126.623 1.00 80.42  ? 191 SER A O   1 
ATOM   1474 C  CB  . SER A 1 191 ? 116.235 101.150 126.652 1.00 80.42  ? 191 SER A CB  1 
ATOM   1475 O  OG  . SER A 1 191 ? 115.390 101.907 125.815 1.00 80.42  ? 191 SER A OG  1 
ATOM   1476 N  N   . ASP A 1 192 ? 114.309 99.779  128.647 1.00 83.87  ? 192 ASP A N   1 
ATOM   1477 C  CA  . ASP A 1 192 ? 113.021 99.769  129.330 1.00 83.87  ? 192 ASP A CA  1 
ATOM   1478 C  C   . ASP A 1 192 ? 112.214 101.013 128.997 1.00 83.87  ? 192 ASP A C   1 
ATOM   1479 O  O   . ASP A 1 192 ? 110.983 101.008 129.099 1.00 83.87  ? 192 ASP A O   1 
ATOM   1480 C  CB  . ASP A 1 192 ? 113.231 99.657  130.835 1.00 83.87  ? 192 ASP A CB  1 
ATOM   1481 C  CG  . ASP A 1 192 ? 113.756 98.308  131.242 1.00 83.87  ? 192 ASP A CG  1 
ATOM   1482 O  OD1 . ASP A 1 192 ? 113.459 97.324  130.541 1.00 83.87  ? 192 ASP A OD1 1 
ATOM   1483 O  OD2 . ASP A 1 192 ? 114.463 98.223  132.264 1.00 83.87  ? 192 ASP A OD2 1 
ATOM   1484 N  N   . GLU A 1 193 ? 112.895 102.090 128.613 1.00 83.77  ? 193 GLU A N   1 
ATOM   1485 C  CA  . GLU A 1 193 ? 112.211 103.279 128.127 1.00 83.77  ? 193 GLU A CA  1 
ATOM   1486 C  C   . GLU A 1 193 ? 111.490 103.006 126.817 1.00 83.77  ? 193 GLU A C   1 
ATOM   1487 O  O   . GLU A 1 193 ? 110.364 103.471 126.615 1.00 83.77  ? 193 GLU A O   1 
ATOM   1488 C  CB  . GLU A 1 193 ? 113.219 104.409 127.955 1.00 83.77  ? 193 GLU A CB  1 
ATOM   1489 C  CG  . GLU A 1 193 ? 112.632 105.704 127.454 1.00 83.77  ? 193 GLU A CG  1 
ATOM   1490 C  CD  . GLU A 1 193 ? 113.678 106.783 127.308 1.00 83.77  ? 193 GLU A CD  1 
ATOM   1491 O  OE1 . GLU A 1 193 ? 114.859 106.505 127.602 1.00 83.77  ? 193 GLU A OE1 1 
ATOM   1492 O  OE2 . GLU A 1 193 ? 113.325 107.904 126.891 1.00 83.77  ? 193 GLU A OE2 1 
ATOM   1493 N  N   . TRP A 1 194 ? 112.118 102.246 125.916 1.00 74.41  ? 194 TRP A N   1 
ATOM   1494 C  CA  . TRP A 1 194 ? 111.510 101.994 124.615 1.00 74.41  ? 194 TRP A CA  1 
ATOM   1495 C  C   . TRP A 1 194 ? 110.344 101.031 124.726 1.00 74.41  ? 194 TRP A C   1 
ATOM   1496 O  O   . TRP A 1 194 ? 109.343 101.189 124.025 1.00 74.41  ? 194 TRP A O   1 
ATOM   1497 C  CB  . TRP A 1 194 ? 112.540 101.449 123.630 1.00 74.41  ? 194 TRP A CB  1 
ATOM   1498 C  CG  . TRP A 1 194 ? 111.983 101.302 122.248 1.00 74.41  ? 194 TRP A CG  1 
ATOM   1499 C  CD1 . TRP A 1 194 ? 111.953 102.251 121.280 1.00 74.41  ? 194 TRP A CD1 1 
ATOM   1500 C  CD2 . TRP A 1 194 ? 111.356 100.143 121.689 1.00 74.41  ? 194 TRP A CD2 1 
ATOM   1501 N  NE1 . TRP A 1 194 ? 111.352 101.761 120.154 1.00 74.41  ? 194 TRP A NE1 1 
ATOM   1502 C  CE2 . TRP A 1 194 ? 110.971 100.468 120.383 1.00 74.41  ? 194 TRP A CE2 1 
ATOM   1503 C  CE3 . TRP A 1 194 ? 111.078 98.865  122.172 1.00 74.41  ? 194 TRP A CE3 1 
ATOM   1504 C  CZ2 . TRP A 1 194 ? 110.337 99.563  119.552 1.00 74.41  ? 194 TRP A CZ2 1 
ATOM   1505 C  CZ3 . TRP A 1 194 ? 110.445 97.975  121.350 1.00 74.41  ? 194 TRP A CZ3 1 
ATOM   1506 C  CH2 . TRP A 1 194 ? 110.082 98.323  120.054 1.00 74.41  ? 194 TRP A CH2 1 
ATOM   1507 N  N   . VAL A 1 195 ? 110.466 100.019 125.582 1.00 74.85  ? 195 VAL A N   1 
ATOM   1508 C  CA  . VAL A 1 195 ? 109.422 99.007  125.700 1.00 74.85  ? 195 VAL A CA  1 
ATOM   1509 C  C   . VAL A 1 195 ? 108.176 99.603  126.334 1.00 74.85  ? 195 VAL A C   1 
ATOM   1510 O  O   . VAL A 1 195 ? 107.049 99.304  125.925 1.00 74.85  ? 195 VAL A O   1 
ATOM   1511 C  CB  . VAL A 1 195 ? 109.957 97.799  126.488 1.00 74.85  ? 195 VAL A CB  1 
ATOM   1512 C  CG1 . VAL A 1 195 ? 108.891 96.751  126.677 1.00 74.85  ? 195 VAL A CG1 1 
ATOM   1513 C  CG2 . VAL A 1 195 ? 111.122 97.200  125.758 1.00 74.85  ? 195 VAL A CG2 1 
ATOM   1514 N  N   . GLU A 1 196 ? 108.357 100.496 127.303 1.00 79.91  ? 196 GLU A N   1 
ATOM   1515 C  CA  . GLU A 1 196 ? 107.216 101.178 127.896 1.00 79.91  ? 196 GLU A CA  1 
ATOM   1516 C  C   . GLU A 1 196 ? 106.607 102.179 126.922 1.00 79.91  ? 196 GLU A C   1 
ATOM   1517 O  O   . GLU A 1 196 ? 105.391 102.390 126.915 1.00 79.91  ? 196 GLU A O   1 
ATOM   1518 C  CB  . GLU A 1 196 ? 107.640 101.859 129.195 1.00 79.91  ? 196 GLU A CB  1 
ATOM   1519 C  CG  . GLU A 1 196 ? 106.506 102.525 129.940 1.00 79.91  ? 196 GLU A CG  1 
ATOM   1520 C  CD  . GLU A 1 196 ? 105.450 101.535 130.407 1.00 79.91  ? 196 GLU A CD  1 
ATOM   1521 O  OE1 . GLU A 1 196 ? 105.800 100.384 130.745 1.00 79.91  ? 196 GLU A OE1 1 
ATOM   1522 O  OE2 . GLU A 1 196 ? 104.256 101.899 130.402 1.00 79.91  ? 196 GLU A OE2 1 
ATOM   1523 N  N   . GLN A 1 197 ? 107.433 102.783 126.073 1.00 77.29  ? 197 GLN A N   1 
ATOM   1524 C  CA  . GLN A 1 197 ? 106.907 103.673 125.047 1.00 77.29  ? 197 GLN A CA  1 
ATOM   1525 C  C   . GLN A 1 197 ? 106.217 102.888 123.938 1.00 77.29  ? 197 GLN A C   1 
ATOM   1526 O  O   . GLN A 1 197 ? 105.240 103.362 123.350 1.00 77.29  ? 197 GLN A O   1 
ATOM   1527 C  CB  . GLN A 1 197 ? 108.038 104.538 124.498 1.00 77.29  ? 197 GLN A CB  1 
ATOM   1528 C  CG  . GLN A 1 197 ? 107.610 105.557 123.479 1.00 77.29  ? 197 GLN A CG  1 
ATOM   1529 C  CD  . GLN A 1 197 ? 106.623 106.549 124.046 1.00 77.29  ? 197 GLN A CD  1 
ATOM   1530 O  OE1 . GLN A 1 197 ? 106.766 107.005 125.178 1.00 77.29  ? 197 GLN A OE1 1 
ATOM   1531 N  NE2 . GLN A 1 197 ? 105.608 106.884 123.263 1.00 77.29  ? 197 GLN A NE2 1 
ATOM   1532 N  N   . TRP A 1 198 ? 106.702 101.680 123.651 1.00 70.79  ? 198 TRP A N   1 
ATOM   1533 C  CA  . TRP A 1 198 ? 106.069 100.828 122.650 1.00 70.79  ? 198 TRP A CA  1 
ATOM   1534 C  C   . TRP A 1 198 ? 104.689 100.379 123.100 1.00 70.79  ? 198 TRP A C   1 
ATOM   1535 O  O   . TRP A 1 198 ? 103.765 100.286 122.288 1.00 70.79  ? 198 TRP A O   1 
ATOM   1536 C  CB  . TRP A 1 198 ? 106.968 99.627  122.361 1.00 70.79  ? 198 TRP A CB  1 
ATOM   1537 C  CG  . TRP A 1 198 ? 106.286 98.396  121.865 1.00 70.79  ? 198 TRP A CG  1 
ATOM   1538 C  CD1 . TRP A 1 198 ? 105.903 97.325  122.603 1.00 70.79  ? 198 TRP A CD1 1 
ATOM   1539 C  CD2 . TRP A 1 198 ? 105.956 98.086  120.513 1.00 70.79  ? 198 TRP A CD2 1 
ATOM   1540 N  NE1 . TRP A 1 198 ? 105.330 96.378  121.805 1.00 70.79  ? 198 TRP A NE1 1 
ATOM   1541 C  CE2 . TRP A 1 198 ? 105.353 96.821  120.513 1.00 70.79  ? 198 TRP A CE2 1 
ATOM   1542 C  CE3 . TRP A 1 198 ? 106.101 98.761  119.304 1.00 70.79  ? 198 TRP A CE3 1 
ATOM   1543 C  CZ2 . TRP A 1 198 ? 104.897 96.218  119.354 1.00 70.79  ? 198 TRP A CZ2 1 
ATOM   1544 C  CZ3 . TRP A 1 198 ? 105.649 98.162  118.159 1.00 70.79  ? 198 TRP A CZ3 1 
ATOM   1545 C  CH2 . TRP A 1 198 ? 105.054 96.903  118.189 1.00 70.79  ? 198 TRP A CH2 1 
ATOM   1546 N  N   . PHE A 1 199 ? 104.525 100.103 124.389 1.00 71.05  ? 199 PHE A N   1 
ATOM   1547 C  CA  . PHE A 1 199 ? 103.221 99.679  124.876 1.00 71.05  ? 199 PHE A CA  1 
ATOM   1548 C  C   . PHE A 1 199 ? 102.272 100.854 125.015 1.00 71.05  ? 199 PHE A C   1 
ATOM   1549 O  O   . PHE A 1 199 ? 101.052 100.672 124.999 1.00 71.05  ? 199 PHE A O   1 
ATOM   1550 C  CB  . PHE A 1 199 ? 103.372 98.951  126.202 1.00 71.05  ? 199 PHE A CB  1 
ATOM   1551 C  CG  . PHE A 1 199 ? 103.724 97.517  126.050 1.00 71.05  ? 199 PHE A CG  1 
ATOM   1552 C  CD1 . PHE A 1 199 ? 102.887 96.662  125.361 1.00 71.05  ? 199 PHE A CD1 1 
ATOM   1553 C  CD2 . PHE A 1 199 ? 104.894 97.020  126.576 1.00 71.05  ? 199 PHE A CD2 1 
ATOM   1554 C  CE1 . PHE A 1 199 ? 103.208 95.338  125.210 1.00 71.05  ? 199 PHE A CE1 1 
ATOM   1555 C  CE2 . PHE A 1 199 ? 105.220 95.698  126.425 1.00 71.05  ? 199 PHE A CE2 1 
ATOM   1556 C  CZ  . PHE A 1 199 ? 104.375 94.857  125.743 1.00 71.05  ? 199 PHE A CZ  1 
ATOM   1557 N  N   . ALA A 1 200 ? 102.809 102.064 125.153 1.00 72.42  ? 200 ALA A N   1 
ATOM   1558 C  CA  . ALA A 1 200 ? 101.956 103.241 125.215 1.00 72.42  ? 200 ALA A CA  1 
ATOM   1559 C  C   . ALA A 1 200 ? 101.370 103.563 123.853 1.00 72.42  ? 200 ALA A C   1 
ATOM   1560 O  O   . ALA A 1 200 ? 100.219 103.995 123.751 1.00 72.42  ? 200 ALA A O   1 
ATOM   1561 C  CB  . ALA A 1 200 ? 102.746 104.429 125.750 1.00 72.42  ? 200 ALA A CB  1 
ATOM   1562 N  N   . LEU A 1 201 ? 102.146 103.346 122.793 1.00 72.94  ? 201 LEU A N   1 
ATOM   1563 C  CA  . LEU A 1 201 ? 101.680 103.662 121.450 1.00 72.94  ? 201 LEU A CA  1 
ATOM   1564 C  C   . LEU A 1 201 ? 100.655 102.653 120.961 1.00 72.94  ? 201 LEU A C   1 
ATOM   1565 O  O   . LEU A 1 201 ? 99.809  102.979 120.126 1.00 72.94  ? 201 LEU A O   1 
ATOM   1566 C  CB  . LEU A 1 201 ? 102.862 103.713 120.494 1.00 72.94  ? 201 LEU A CB  1 
ATOM   1567 C  CG  . LEU A 1 201 ? 103.816 104.890 120.600 1.00 72.94  ? 201 LEU A CG  1 
ATOM   1568 C  CD1 . LEU A 1 201 ? 105.001 104.660 119.700 1.00 72.94  ? 201 LEU A CD1 1 
ATOM   1569 C  CD2 . LEU A 1 201 ? 103.105 106.154 120.224 1.00 72.94  ? 201 LEU A CD2 1 
ATOM   1570 N  N   . LEU A 1 202 ? 100.721 101.420 121.458 1.00 71.63  ? 202 LEU A N   1 
ATOM   1571 C  CA  . LEU A 1 202 ? 99.750  100.413 121.051 1.00 71.63  ? 202 LEU A CA  1 
ATOM   1572 C  C   . LEU A 1 202 ? 98.378  100.709 121.631 1.00 71.63  ? 202 LEU A C   1 
ATOM   1573 O  O   . LEU A 1 202 ? 97.356  100.436 120.997 1.00 71.63  ? 202 LEU A O   1 
ATOM   1574 C  CB  . LEU A 1 202 ? 100.213 99.026  121.485 1.00 71.63  ? 202 LEU A CB  1 
ATOM   1575 C  CG  . LEU A 1 202 ? 101.387 98.381  120.764 1.00 71.63  ? 202 LEU A CG  1 
ATOM   1576 C  CD1 . LEU A 1 202 ? 101.929 97.279  121.624 1.00 71.63  ? 202 LEU A CD1 1 
ATOM   1577 C  CD2 . LEU A 1 202 ? 100.945 97.828  119.446 1.00 71.63  ? 202 LEU A CD2 1 
ATOM   1578 N  N   . SER A 1 203 ? 98.333  101.266 122.838 1.00 74.72  ? 203 SER A N   1 
ATOM   1579 C  CA  . SER A 1 203 ? 97.049  101.590 123.442 1.00 74.72  ? 203 SER A CA  1 
ATOM   1580 C  C   . SER A 1 203 ? 96.514  102.913 122.918 1.00 74.72  ? 203 SER A C   1 
ATOM   1581 O  O   . SER A 1 203 ? 95.302  103.147 122.932 1.00 74.72  ? 203 SER A O   1 
ATOM   1582 C  CB  . SER A 1 203 ? 97.182  101.633 124.958 1.00 74.72  ? 203 SER A CB  1 
ATOM   1583 O  OG  . SER A 1 203 ? 97.643  102.902 125.370 1.00 74.72  ? 203 SER A OG  1 
ATOM   1584 N  N   . THR A 1 204 ? 97.405  103.796 122.464 1.00 73.54  ? 204 THR A N   1 
ATOM   1585 C  CA  . THR A 1 204 ? 96.976  105.063 121.885 1.00 73.54  ? 204 THR A CA  1 
ATOM   1586 C  C   . THR A 1 204 ? 96.264  104.847 120.560 1.00 73.54  ? 204 THR A C   1 
ATOM   1587 O  O   . THR A 1 204 ? 95.165  105.367 120.343 1.00 73.54  ? 204 THR A O   1 
ATOM   1588 C  CB  . THR A 1 204 ? 98.181  105.981 121.697 1.00 73.54  ? 204 THR A CB  1 
ATOM   1589 O  OG1 . THR A 1 204 ? 98.699  106.351 122.976 1.00 73.54  ? 204 THR A OG1 1 
ATOM   1590 C  CG2 . THR A 1 204 ? 97.804  107.228 120.937 1.00 73.54  ? 204 THR A CG2 1 
ATOM   1591 N  N   . TYR A 1 205 ? 96.860  104.064 119.674 1.00 73.37  ? 205 TYR A N   1 
ATOM   1592 C  CA  . TYR A 1 205 ? 96.317  103.850 118.346 1.00 73.37  ? 205 TYR A CA  1 
ATOM   1593 C  C   . TYR A 1 205 ? 95.468  102.597 118.244 1.00 73.37  ? 205 TYR A C   1 
ATOM   1594 O  O   . TYR A 1 205 ? 94.941  102.315 117.169 1.00 73.37  ? 205 TYR A O   1 
ATOM   1595 C  CB  . TYR A 1 205 ? 97.453  103.803 117.330 1.00 73.37  ? 205 TYR A CB  1 
ATOM   1596 C  CG  . TYR A 1 205 ? 98.185  105.111 117.240 1.00 73.37  ? 205 TYR A CG  1 
ATOM   1597 C  CD1 . TYR A 1 205 ? 97.629  106.185 116.573 1.00 73.37  ? 205 TYR A CD1 1 
ATOM   1598 C  CD2 . TYR A 1 205 ? 99.415  105.281 117.846 1.00 73.37  ? 205 TYR A CD2 1 
ATOM   1599 C  CE1 . TYR A 1 205 ? 98.283  107.384 116.498 1.00 73.37  ? 205 TYR A CE1 1 
ATOM   1600 C  CE2 . TYR A 1 205 ? 100.077 106.477 117.775 1.00 73.37  ? 205 TYR A CE2 1 
ATOM   1601 C  CZ  . TYR A 1 205 ? 99.505  107.524 117.100 1.00 73.37  ? 205 TYR A CZ  1 
ATOM   1602 O  OH  . TYR A 1 205 ? 100.159 108.724 117.026 1.00 73.37  ? 205 TYR A OH  1 
ATOM   1603 N  N   . GLY A 1 206 ? 95.312  101.851 119.329 1.00 72.71  ? 206 GLY A N   1 
ATOM   1604 C  CA  . GLY A 1 206 ? 94.410  100.717 119.335 1.00 72.71  ? 206 GLY A CA  1 
ATOM   1605 C  C   . GLY A 1 206 ? 94.890  99.536  118.524 1.00 72.71  ? 206 GLY A C   1 
ATOM   1606 O  O   . GLY A 1 206 ? 94.081  98.827  117.920 1.00 72.71  ? 206 GLY A O   1 
ATOM   1607 N  N   . LEU A 1 207 ? 96.194  99.309  118.499 1.00 71.09  ? 207 LEU A N   1 
ATOM   1608 C  CA  . LEU A 1 207 ? 96.785  98.226  117.737 1.00 71.09  ? 207 LEU A CA  1 
ATOM   1609 C  C   . LEU A 1 207 ? 97.217  97.109  118.671 1.00 71.09  ? 207 LEU A C   1 
ATOM   1610 O  O   . LEU A 1 207 ? 97.607  97.351  119.813 1.00 71.09  ? 207 LEU A O   1 
ATOM   1611 C  CB  . LEU A 1 207 ? 97.985  98.720  116.937 1.00 71.09  ? 207 LEU A CB  1 
ATOM   1612 C  CG  . LEU A 1 207 ? 97.689  99.888  116.009 1.00 71.09  ? 207 LEU A CG  1 
ATOM   1613 C  CD1 . LEU A 1 207 ? 98.963  100.461 115.465 1.00 71.09  ? 207 LEU A CD1 1 
ATOM   1614 C  CD2 . LEU A 1 207 ? 96.796  99.429  114.893 1.00 71.09  ? 207 LEU A CD2 1 
ATOM   1615 N  N   . GLU A 1 208 ? 97.129  95.880  118.183 1.00 75.31  ? 208 GLU A N   1 
ATOM   1616 C  CA  . GLU A 1 208 ? 97.691  94.758  118.895 1.00 75.31  ? 208 GLU A CA  1 
ATOM   1617 C  C   . GLU A 1 208 ? 98.821  94.165  118.069 1.00 75.31  ? 208 GLU A C   1 
ATOM   1618 O  O   . GLU A 1 208 ? 98.719  94.105  116.839 1.00 75.31  ? 208 GLU A O   1 
ATOM   1619 C  CB  . GLU A 1 208 ? 96.636  93.685  119.204 1.00 75.31  ? 208 GLU A CB  1 
ATOM   1620 C  CG  . GLU A 1 208 ? 95.869  93.164  118.016 1.00 75.31  ? 208 GLU A CG  1 
ATOM   1621 C  CD  . GLU A 1 208 ? 95.306  91.778  118.244 1.00 75.31  ? 208 GLU A CD  1 
ATOM   1622 O  OE1 . GLU A 1 208 ? 94.200  91.497  117.740 1.00 75.31  ? 208 GLU A OE1 1 
ATOM   1623 O  OE2 . GLU A 1 208 ? 95.968  90.964  118.918 1.00 75.31  ? 208 GLU A OE2 1 
ATOM   1624 N  N   . PRO A 1 209 ? 99.923  93.770  118.688 1.00 72.35  ? 209 PRO A N   1 
ATOM   1625 C  CA  . PRO A 1 209 ? 101.007 93.160  117.921 1.00 72.35  ? 209 PRO A CA  1 
ATOM   1626 C  C   . PRO A 1 209 ? 100.662 91.733  117.545 1.00 72.35  ? 209 PRO A C   1 
ATOM   1627 O  O   . PRO A 1 209 ? 100.102 90.983  118.343 1.00 72.35  ? 209 PRO A O   1 
ATOM   1628 C  CB  . PRO A 1 209 ? 102.192 93.224  118.884 1.00 72.35  ? 209 PRO A CB  1 
ATOM   1629 C  CG  . PRO A 1 209 ? 101.601 93.314  120.208 1.00 72.35  ? 209 PRO A CG  1 
ATOM   1630 C  CD  . PRO A 1 209 ? 100.292 93.992  120.092 1.00 72.35  ? 209 PRO A CD  1 
ATOM   1631 N  N   . THR A 1 210 ? 100.978 91.364  116.305 1.00 72.42  ? 210 THR A N   1 
ATOM   1632 C  CA  . THR A 1 210 ? 100.635 90.037  115.808 1.00 72.42  ? 210 THR A CA  1 
ATOM   1633 C  C   . THR A 1 210 ? 101.859 89.178  115.523 1.00 72.42  ? 210 THR A C   1 
ATOM   1634 O  O   . THR A 1 210 ? 102.018 88.131  116.148 1.00 72.42  ? 210 THR A O   1 
ATOM   1635 C  CB  . THR A 1 210 ? 99.770  90.151  114.549 1.00 72.42  ? 210 THR A CB  1 
ATOM   1636 O  OG1 . THR A 1 210 ? 100.488 90.864  113.543 1.00 72.42  ? 210 THR A OG1 1 
ATOM   1637 C  CG2 . THR A 1 210 ? 98.498  90.887  114.848 1.00 72.42  ? 210 THR A CG2 1 
ATOM   1638 N  N   . ASN A 1 211 ? 102.750 89.596  114.636 1.00 72.01  ? 211 ASN A N   1 
ATOM   1639 C  CA  . ASN A 1 211 ? 103.807 88.726  114.146 1.00 72.01  ? 211 ASN A CA  1 
ATOM   1640 C  C   . ASN A 1 211 ? 105.148 89.437  114.192 1.00 72.01  ? 211 ASN A C   1 
ATOM   1641 O  O   . ASN A 1 211 ? 105.258 90.594  113.786 1.00 72.01  ? 211 ASN A O   1 
ATOM   1642 C  CB  . ASN A 1 211 ? 103.505 88.271  112.720 1.00 72.01  ? 211 ASN A CB  1 
ATOM   1643 C  CG  . ASN A 1 211 ? 104.571 87.367  112.158 1.00 72.01  ? 211 ASN A CG  1 
ATOM   1644 O  OD1 . ASN A 1 211 ? 104.715 86.232  112.580 1.00 72.01  ? 211 ASN A OD1 1 
ATOM   1645 N  ND2 . ASN A 1 211 ? 105.318 87.864  111.190 1.00 72.01  ? 211 ASN A ND2 1 
ATOM   1646 N  N   . MET A 1 212 ? 106.165 88.739  114.686 1.00 73.86  ? 212 MET A N   1 
ATOM   1647 C  CA  . MET A 1 212 ? 107.531 89.238  114.704 1.00 73.86  ? 212 MET A CA  1 
ATOM   1648 C  C   . MET A 1 212 ? 108.388 88.351  113.817 1.00 73.86  ? 212 MET A C   1 
ATOM   1649 O  O   . MET A 1 212 ? 108.465 87.141  114.037 1.00 73.86  ? 212 MET A O   1 
ATOM   1650 C  CB  . MET A 1 212 ? 108.094 89.273  116.121 1.00 73.86  ? 212 MET A CB  1 
ATOM   1651 C  CG  . MET A 1 212 ? 109.118 90.366  116.332 1.00 73.86  ? 212 MET A CG  1 
ATOM   1652 S  SD  . MET A 1 212 ? 110.111 90.145  117.810 1.00 73.86  ? 212 MET A SD  1 
ATOM   1653 C  CE  . MET A 1 212 ? 111.205 88.842  117.277 1.00 73.86  ? 212 MET A CE  1 
ATOM   1654 N  N   . GLY A 1 213 ? 109.032 88.953  112.824 1.00 73.97  ? 213 GLY A N   1 
ATOM   1655 C  CA  . GLY A 1 213 ? 109.853 88.183  111.911 1.00 73.97  ? 213 GLY A CA  1 
ATOM   1656 C  C   . GLY A 1 213 ? 111.244 87.953  112.469 1.00 73.97  ? 213 GLY A C   1 
ATOM   1657 O  O   . GLY A 1 213 ? 111.847 88.833  113.079 1.00 73.97  ? 213 GLY A O   1 
ATOM   1658 N  N   . SER A 1 214 ? 111.760 86.753  112.240 1.00 74.90  ? 214 SER A N   1 
ATOM   1659 C  CA  . SER A 1 214 ? 113.037 86.334  112.786 1.00 74.90  ? 214 SER A CA  1 
ATOM   1660 C  C   . SER A 1 214 ? 113.851 85.649  111.703 1.00 74.90  ? 214 SER A C   1 
ATOM   1661 O  O   . SER A 1 214 ? 113.314 85.162  110.709 1.00 74.90  ? 214 SER A O   1 
ATOM   1662 C  CB  . SER A 1 214 ? 112.845 85.392  113.971 1.00 74.90  ? 214 SER A CB  1 
ATOM   1663 O  OG  . SER A 1 214 ? 114.082 84.878  114.414 1.00 74.90  ? 214 SER A OG  1 
ATOM   1664 N  N   . TRP A 1 215 ? 115.163 85.619  111.906 1.00 75.35  ? 215 TRP A N   1 
ATOM   1665 C  CA  . TRP A 1 215 ? 116.079 84.946  111.000 1.00 75.35  ? 215 TRP A CA  1 
ATOM   1666 C  C   . TRP A 1 215 ? 116.966 84.005  111.788 1.00 75.35  ? 215 TRP A C   1 
ATOM   1667 O  O   . TRP A 1 215 ? 117.290 84.267  112.946 1.00 75.35  ? 215 TRP A O   1 
ATOM   1668 C  CB  . TRP A 1 215 ? 116.948 85.933  110.233 1.00 75.35  ? 215 TRP A CB  1 
ATOM   1669 C  CG  . TRP A 1 215 ? 116.205 86.661  109.200 1.00 75.35  ? 215 TRP A CG  1 
ATOM   1670 C  CD1 . TRP A 1 215 ? 116.085 86.326  107.893 1.00 75.35  ? 215 TRP A CD1 1 
ATOM   1671 C  CD2 . TRP A 1 215 ? 115.450 87.852  109.383 1.00 75.35  ? 215 TRP A CD2 1 
ATOM   1672 N  NE1 . TRP A 1 215 ? 115.302 87.239  107.243 1.00 75.35  ? 215 TRP A NE1 1 
ATOM   1673 C  CE2 . TRP A 1 215 ? 114.899 88.189  108.140 1.00 75.35  ? 215 TRP A CE2 1 
ATOM   1674 C  CE3 . TRP A 1 215 ? 115.187 88.671  110.482 1.00 75.35  ? 215 TRP A CE3 1 
ATOM   1675 C  CZ2 . TRP A 1 215 ? 114.103 89.306  107.963 1.00 75.35  ? 215 TRP A CZ2 1 
ATOM   1676 C  CZ3 . TRP A 1 215 ? 114.402 89.775  110.305 1.00 75.35  ? 215 TRP A CZ3 1 
ATOM   1677 C  CH2 . TRP A 1 215 ? 113.867 90.087  109.056 1.00 75.35  ? 215 TRP A CH2 1 
ATOM   1678 N  N   . ILE A 1 216 ? 117.338 82.903  111.161 1.00 78.48  ? 216 ILE A N   1 
ATOM   1679 C  CA  . ILE A 1 216 ? 118.365 82.008  111.669 1.00 78.48  ? 216 ILE A CA  1 
ATOM   1680 C  C   . ILE A 1 216 ? 119.434 81.954  110.589 1.00 78.48  ? 216 ILE A C   1 
ATOM   1681 O  O   . ILE A 1 216 ? 119.332 81.175  109.638 1.00 78.48  ? 216 ILE A O   1 
ATOM   1682 C  CB  . ILE A 1 216 ? 117.815 80.617  111.991 1.00 78.48  ? 216 ILE A CB  1 
ATOM   1683 C  CG1 . ILE A 1 216 ? 116.659 80.718  112.976 1.00 78.48  ? 216 ILE A CG1 1 
ATOM   1684 C  CG2 . ILE A 1 216 ? 118.890 79.745  112.585 1.00 78.48  ? 216 ILE A CG2 1 
ATOM   1685 C  CD1 . ILE A 1 216 ? 115.629 79.666  112.782 1.00 78.48  ? 216 ILE A CD1 1 
ATOM   1686 N  N   . ASP A 1 217 ? 120.452 82.795  110.717 1.00 81.78  ? 217 ASP A N   1 
ATOM   1687 C  CA  . ASP A 1 217 ? 121.462 82.953  109.676 1.00 81.78  ? 217 ASP A CA  1 
ATOM   1688 C  C   . ASP A 1 217 ? 122.445 81.798  109.738 1.00 81.78  ? 217 ASP A C   1 
ATOM   1689 O  O   . ASP A 1 217 ? 123.371 81.809  110.547 1.00 81.78  ? 217 ASP A O   1 
ATOM   1690 C  CB  . ASP A 1 217 ? 122.192 84.278  109.843 1.00 81.78  ? 217 ASP A CB  1 
ATOM   1691 C  CG  . ASP A 1 217 ? 121.276 85.460  109.725 1.00 81.78  ? 217 ASP A CG  1 
ATOM   1692 O  OD1 . ASP A 1 217 ? 120.637 85.613  108.668 1.00 81.78  ? 217 ASP A OD1 1 
ATOM   1693 O  OD2 . ASP A 1 217 ? 121.192 86.242  110.690 1.00 81.78  ? 217 ASP A OD2 1 
ATOM   1694 N  N   . THR A 1 218 ? 122.264 80.809  108.869 1.00 82.73  ? 218 THR A N   1 
ATOM   1695 C  CA  . THR A 1 218 ? 123.128 79.640  108.897 1.00 82.73  ? 218 THR A CA  1 
ATOM   1696 C  C   . THR A 1 218 ? 124.509 79.916  108.329 1.00 82.73  ? 218 THR A C   1 
ATOM   1697 O  O   . THR A 1 218 ? 125.442 79.167  108.622 1.00 82.73  ? 218 THR A O   1 
ATOM   1698 C  CB  . THR A 1 218 ? 122.482 78.488  108.138 1.00 82.73  ? 218 THR A CB  1 
ATOM   1699 O  OG1 . THR A 1 218 ? 122.326 78.847  106.764 1.00 82.73  ? 218 THR A OG1 1 
ATOM   1700 C  CG2 . THR A 1 218 ? 121.133 78.181  108.725 1.00 82.73  ? 218 THR A CG2 1 
ATOM   1701 N  N   . ARG A 1 219 ? 124.666 80.972  107.540 1.00 81.83  ? 219 ARG A N   1 
ATOM   1702 C  CA  . ARG A 1 219 ? 125.965 81.377  107.027 1.00 81.83  ? 219 ARG A CA  1 
ATOM   1703 C  C   . ARG A 1 219 ? 126.557 82.507  107.849 1.00 81.83  ? 219 ARG A C   1 
ATOM   1704 O  O   . ARG A 1 219 ? 127.172 83.422  107.300 1.00 81.83  ? 219 ARG A O   1 
ATOM   1705 C  CB  . ARG A 1 219 ? 125.863 81.780  105.560 1.00 81.83  ? 219 ARG A CB  1 
ATOM   1706 C  CG  . ARG A 1 219 ? 125.475 80.647  104.653 1.00 81.83  ? 219 ARG A CG  1 
ATOM   1707 C  CD  . ARG A 1 219 ? 125.268 81.127  103.248 1.00 81.83  ? 219 ARG A CD  1 
ATOM   1708 N  NE  . ARG A 1 219 ? 124.292 80.310  102.547 1.00 81.83  ? 219 ARG A NE  1 
ATOM   1709 C  CZ  . ARG A 1 219 ? 123.543 80.749  101.547 1.00 81.83  ? 219 ARG A CZ  1 
ATOM   1710 N  NH1 . ARG A 1 219 ? 123.663 81.997  101.131 1.00 81.83  ? 219 ARG A NH1 1 
ATOM   1711 N  NH2 . ARG A 1 219 ? 122.676 79.941  100.966 1.00 81.83  ? 219 ARG A NH2 1 
ATOM   1712 N  N   . LEU A 1 220 ? 126.348 82.461  109.163 1.00 79.64  ? 220 LEU A N   1 
ATOM   1713 C  CA  . LEU A 1 220 ? 126.806 83.523  110.048 1.00 79.64  ? 220 LEU A CA  1 
ATOM   1714 C  C   . LEU A 1 220 ? 128.323 83.572  110.119 1.00 79.64  ? 220 LEU A C   1 
ATOM   1715 O  O   . LEU A 1 220 ? 128.913 84.654  110.138 1.00 79.64  ? 220 LEU A O   1 
ATOM   1716 C  CB  . LEU A 1 220 ? 126.214 83.317  111.436 1.00 79.64  ? 220 LEU A CB  1 
ATOM   1717 C  CG  . LEU A 1 220 ? 126.461 84.394  112.482 1.00 79.64  ? 220 LEU A CG  1 
ATOM   1718 C  CD1 . LEU A 1 220 ? 125.580 85.577  112.216 1.00 79.64  ? 220 LEU A CD1 1 
ATOM   1719 C  CD2 . LEU A 1 220 ? 126.199 83.840  113.858 1.00 79.64  ? 220 LEU A CD2 1 
ATOM   1720 N  N   . HIS A 1 221 ? 128.972 82.412  110.144 1.00 82.33  ? 221 HIS A N   1 
ATOM   1721 C  CA  . HIS A 1 221 ? 130.425 82.332  110.192 1.00 82.33  ? 221 HIS A CA  1 
ATOM   1722 C  C   . HIS A 1 221 ? 130.978 81.515  109.037 1.00 82.33  ? 221 HIS A C   1 
ATOM   1723 O  O   . HIS A 1 221 ? 131.860 80.682  109.229 1.00 82.33  ? 221 HIS A O   1 
ATOM   1724 C  CB  . HIS A 1 221 ? 130.880 81.755  111.526 1.00 82.33  ? 221 HIS A CB  1 
ATOM   1725 C  CG  . HIS A 1 221 ? 130.554 82.629  112.689 1.00 82.33  ? 221 HIS A CG  1 
ATOM   1726 N  ND1 . HIS A 1 221 ? 131.242 83.790  112.959 1.00 82.33  ? 221 HIS A ND1 1 
ATOM   1727 C  CD2 . HIS A 1 221 ? 129.599 82.527  113.642 1.00 82.33  ? 221 HIS A CD2 1 
ATOM   1728 C  CE1 . HIS A 1 221 ? 130.733 84.360  114.035 1.00 82.33  ? 221 HIS A CE1 1 
ATOM   1729 N  NE2 . HIS A 1 221 ? 129.735 83.613  114.469 1.00 82.33  ? 221 HIS A NE2 1 
ATOM   1730 N  N   . SER A 1 222 ? 130.470 81.750  107.834 1.00 83.33  ? 222 SER A N   1 
ATOM   1731 C  CA  . SER A 1 222 ? 130.870 80.963  106.683 1.00 83.33  ? 222 SER A CA  1 
ATOM   1732 C  C   . SER A 1 222 ? 132.139 81.490  106.034 1.00 83.33  ? 222 SER A C   1 
ATOM   1733 O  O   . SER A 1 222 ? 132.851 80.728  105.375 1.00 83.33  ? 222 SER A O   1 
ATOM   1734 C  CB  . SER A 1 222 ? 129.739 80.938  105.664 1.00 83.33  ? 222 SER A CB  1 
ATOM   1735 O  OG  . SER A 1 222 ? 130.122 80.224  104.509 1.00 83.33  ? 222 SER A OG  1 
ATOM   1736 N  N   . SER A 1 223 ? 132.439 82.772  106.199 1.00 82.71  ? 223 SER A N   1 
ATOM   1737 C  CA  . SER A 1 223 ? 133.564 83.380  105.509 1.00 82.71  ? 223 SER A CA  1 
ATOM   1738 C  C   . SER A 1 223 ? 134.810 83.376  106.379 1.00 82.71  ? 223 SER A C   1 
ATOM   1739 O  O   . SER A 1 223 ? 134.741 83.383  107.608 1.00 82.71  ? 223 SER A O   1 
ATOM   1740 C  CB  . SER A 1 223 ? 133.235 84.812  105.097 1.00 82.71  ? 223 SER A CB  1 
ATOM   1741 O  OG  . SER A 1 223 ? 132.191 84.841  104.147 1.00 82.71  ? 223 SER A OG  1 
ATOM   1742 N  N   . GLY A 1 224 ? 135.961 83.364  105.719 1.00 89.29  ? 224 GLY A N   1 
ATOM   1743 C  CA  . GLY A 1 224 ? 137.224 83.502  106.396 1.00 89.29  ? 224 GLY A CA  1 
ATOM   1744 C  C   . GLY A 1 224 ? 138.023 82.222  106.455 1.00 89.29  ? 224 GLY A C   1 
ATOM   1745 O  O   . GLY A 1 224 ? 137.628 81.187  105.914 1.00 89.29  ? 224 GLY A O   1 
ATOM   1746 N  N   . PRO A 1 225 ? 139.183 82.278  107.110 1.00 95.31  ? 225 PRO A N   1 
ATOM   1747 C  CA  . PRO A 1 225 ? 139.978 81.054  107.278 1.00 95.31  ? 225 PRO A CA  1 
ATOM   1748 C  C   . PRO A 1 225 ? 139.370 80.101  108.283 1.00 95.31  ? 225 PRO A C   1 
ATOM   1749 O  O   . PRO A 1 225 ? 139.505 78.881  108.144 1.00 95.31  ? 225 PRO A O   1 
ATOM   1750 C  CB  . PRO A 1 225 ? 141.339 81.584  107.750 1.00 95.31  ? 225 PRO A CB  1 
ATOM   1751 C  CG  . PRO A 1 225 ? 141.298 83.063  107.528 1.00 95.31  ? 225 PRO A CG  1 
ATOM   1752 C  CD  . PRO A 1 225 ? 139.875 83.455  107.646 1.00 95.31  ? 225 PRO A CD  1 
ATOM   1753 N  N   . ASN A 1 226 ? 138.701 80.633  109.300 1.00 95.18  ? 226 ASN A N   1 
ATOM   1754 C  CA  . ASN A 1 226 ? 138.030 79.830  110.307 1.00 95.18  ? 226 ASN A CA  1 
ATOM   1755 C  C   . ASN A 1 226 ? 136.552 79.655  110.008 1.00 95.18  ? 226 ASN A C   1 
ATOM   1756 O  O   . ASN A 1 226 ? 135.749 79.549  110.939 1.00 95.18  ? 226 ASN A O   1 
ATOM   1757 C  CB  . ASN A 1 226 ? 138.219 80.458  111.684 1.00 95.18  ? 226 ASN A CB  1 
ATOM   1758 C  CG  . ASN A 1 226 ? 139.632 80.934  111.909 1.00 95.18  ? 226 ASN A CG  1 
ATOM   1759 O  OD1 . ASN A 1 226 ? 140.510 80.152  112.266 1.00 95.18  ? 226 ASN A OD1 1 
ATOM   1760 N  ND2 . ASN A 1 226 ? 139.863 82.222  111.697 1.00 95.18  ? 226 ASN A ND2 1 
ATOM   1761 N  N   . GLY A 1 227 ? 136.180 79.641  108.732 1.00 91.89  ? 227 GLY A N   1 
ATOM   1762 C  CA  . GLY A 1 227 ? 134.797 79.517  108.327 1.00 91.89  ? 227 GLY A CA  1 
ATOM   1763 C  C   . GLY A 1 227 ? 134.190 78.183  108.690 1.00 91.89  ? 227 GLY A C   1 
ATOM   1764 O  O   . GLY A 1 227 ? 134.767 77.131  108.408 1.00 91.89  ? 227 GLY A O   1 
ATOM   1765 N  N   . ARG A 1 228 ? 133.024 78.216  109.325 1.00 92.17  ? 228 ARG A N   1 
ATOM   1766 C  CA  . ARG A 1 228 ? 132.384 77.013  109.824 1.00 92.17  ? 228 ARG A CA  1 
ATOM   1767 C  C   . ARG A 1 228 ? 130.888 77.108  109.588 1.00 92.17  ? 228 ARG A C   1 
ATOM   1768 O  O   . ARG A 1 228 ? 130.373 78.125  109.122 1.00 92.17  ? 228 ARG A O   1 
ATOM   1769 C  CB  . ARG A 1 228 ? 132.664 76.812  111.310 1.00 92.17  ? 228 ARG A CB  1 
ATOM   1770 C  CG  . ARG A 1 228 ? 132.467 78.067  112.115 1.00 92.17  ? 228 ARG A CG  1 
ATOM   1771 C  CD  . ARG A 1 228 ? 132.829 77.856  113.558 1.00 92.17  ? 228 ARG A CD  1 
ATOM   1772 N  NE  . ARG A 1 228 ? 132.599 79.060  114.344 1.00 92.17  ? 228 ARG A NE  1 
ATOM   1773 C  CZ  . ARG A 1 228 ? 131.442 79.361  114.920 1.00 92.17  ? 228 ARG A CZ  1 
ATOM   1774 N  NH1 . ARG A 1 228 ? 130.406 78.543  114.799 1.00 92.17  ? 228 ARG A NH1 1 
ATOM   1775 N  NH2 . ARG A 1 228 ? 131.321 80.481  115.618 1.00 92.17  ? 228 ARG A NH2 1 
ATOM   1776 N  N   . ASP A 1 229 ? 130.194 76.031  109.917 1.00 93.01  ? 229 ASP A N   1 
ATOM   1777 C  CA  . ASP A 1 229 ? 128.751 76.012  109.780 1.00 93.01  ? 229 ASP A CA  1 
ATOM   1778 C  C   . ASP A 1 229 ? 128.086 76.185  111.138 1.00 93.01  ? 229 ASP A C   1 
ATOM   1779 O  O   . ASP A 1 229 ? 128.638 75.824  112.178 1.00 93.01  ? 229 ASP A O   1 
ATOM   1780 C  CB  . ASP A 1 229 ? 128.294 74.713  109.132 1.00 93.01  ? 229 ASP A CB  1 
ATOM   1781 C  CG  . ASP A 1 229 ? 127.128 74.915  108.207 1.00 93.01  ? 229 ASP A CG  1 
ATOM   1782 O  OD1 . ASP A 1 229 ? 126.571 76.029  108.194 1.00 93.01  ? 229 ASP A OD1 1 
ATOM   1783 O  OD2 . ASP A 1 229 ? 126.769 73.964  107.487 1.00 93.01  ? 229 ASP A OD2 1 
ATOM   1784 N  N   . MET A 1 230 ? 126.888 76.759  111.114 1.00 89.67  ? 230 MET A N   1 
ATOM   1785 C  CA  . MET A 1 230 ? 126.116 76.958  112.330 1.00 89.67  ? 230 MET A CA  1 
ATOM   1786 C  C   . MET A 1 230 ? 125.601 75.624  112.843 1.00 89.67  ? 230 MET A C   1 
ATOM   1787 O  O   . MET A 1 230 ? 125.075 74.812  112.081 1.00 89.67  ? 230 MET A O   1 
ATOM   1788 C  CB  . MET A 1 230 ? 124.954 77.916  112.067 1.00 89.67  ? 230 MET A CB  1 
ATOM   1789 C  CG  . MET A 1 230 ? 123.929 77.993  113.180 1.00 89.67  ? 230 MET A CG  1 
ATOM   1790 S  SD  . MET A 1 230 ? 122.617 79.190  112.906 1.00 89.67  ? 230 MET A SD  1 
ATOM   1791 C  CE  . MET A 1 230 ? 123.348 80.654  113.615 1.00 89.67  ? 230 MET A CE  1 
ATOM   1792 N  N   . THR A 1 231 ? 125.776 75.391  114.137 1.00 89.05  ? 231 THR A N   1 
ATOM   1793 C  CA  . THR A 1 231 ? 125.337 74.161  114.771 1.00 89.05  ? 231 THR A CA  1 
ATOM   1794 C  C   . THR A 1 231 ? 123.939 74.338  115.341 1.00 89.05  ? 231 THR A C   1 
ATOM   1795 O  O   . THR A 1 231 ? 123.331 75.404  115.241 1.00 89.05  ? 231 THR A O   1 
ATOM   1796 C  CB  . THR A 1 231 ? 126.304 73.738  115.876 1.00 89.05  ? 231 THR A CB  1 
ATOM   1797 O  OG1 . THR A 1 231 ? 126.175 74.625  116.988 1.00 89.05  ? 231 THR A OG1 1 
ATOM   1798 C  CG2 . THR A 1 231 ? 127.720 73.793  115.374 1.00 89.05  ? 231 THR A CG2 1 
ATOM   1799 N  N   . VAL A 1 232 ? 123.434 73.264  115.943 1.00 88.89  ? 232 VAL A N   1 
ATOM   1800 C  CA  . VAL A 1 232 ? 122.077 73.267  116.477 1.00 88.89  ? 232 VAL A CA  1 
ATOM   1801 C  C   . VAL A 1 232 ? 121.980 74.160  117.703 1.00 88.89  ? 232 VAL A C   1 
ATOM   1802 O  O   . VAL A 1 232 ? 121.010 74.907  117.868 1.00 88.89  ? 232 VAL A O   1 
ATOM   1803 C  CB  . VAL A 1 232 ? 121.637 71.829  116.789 1.00 88.89  ? 232 VAL A CB  1 
ATOM   1804 C  CG1 . VAL A 1 232 ? 120.208 71.802  117.243 1.00 88.89  ? 232 VAL A CG1 1 
ATOM   1805 C  CG2 . VAL A 1 232 ? 121.813 70.967  115.569 1.00 88.89  ? 232 VAL A CG2 1 
ATOM   1806 N  N   . GLU A 1 233 ? 122.991 74.112  118.570 1.00 91.06  ? 233 GLU A N   1 
ATOM   1807 C  CA  . GLU A 1 233 ? 122.962 74.883  119.808 1.00 91.06  ? 233 GLU A CA  1 
ATOM   1808 C  C   . GLU A 1 233 ? 123.077 76.374  119.534 1.00 91.06  ? 233 GLU A C   1 
ATOM   1809 O  O   . GLU A 1 233 ? 122.463 77.190  120.224 1.00 91.06  ? 233 GLU A O   1 
ATOM   1810 C  CB  . GLU A 1 233 ? 124.085 74.418  120.732 1.00 91.06  ? 233 GLU A CB  1 
ATOM   1811 C  CG  . GLU A 1 233 ? 123.964 72.972  121.164 1.00 91.06  ? 233 GLU A CG  1 
ATOM   1812 C  CD  . GLU A 1 233 ? 124.685 72.011  120.235 1.00 91.06  ? 233 GLU A CD  1 
ATOM   1813 O  OE1 . GLU A 1 233 ? 125.118 72.441  119.147 1.00 91.06  ? 233 GLU A OE1 1 
ATOM   1814 O  OE2 . GLU A 1 233 ? 124.811 70.822  120.588 1.00 91.06  ? 233 GLU A OE2 1 
ATOM   1815 N  N   . GLU A 1 234 ? 123.852 76.748  118.520 1.00 90.69  ? 234 GLU A N   1 
ATOM   1816 C  CA  . GLU A 1 234 ? 123.893 78.145  118.117 1.00 90.69  ? 234 GLU A CA  1 
ATOM   1817 C  C   . GLU A 1 234 ? 122.644 78.521  117.341 1.00 90.69  ? 234 GLU A C   1 
ATOM   1818 O  O   . GLU A 1 234 ? 122.271 79.697  117.283 1.00 90.69  ? 234 GLU A O   1 
ATOM   1819 C  CB  . GLU A 1 234 ? 125.139 78.412  117.282 1.00 90.69  ? 234 GLU A CB  1 
ATOM   1820 C  CG  . GLU A 1 234 ? 126.419 77.988  117.952 1.00 90.69  ? 234 GLU A CG  1 
ATOM   1821 C  CD  . GLU A 1 234 ? 127.466 77.540  116.962 1.00 90.69  ? 234 GLU A CD  1 
ATOM   1822 O  OE1 . GLU A 1 234 ? 127.185 77.557  115.747 1.00 90.69  ? 234 GLU A OE1 1 
ATOM   1823 O  OE2 . GLU A 1 234 ? 128.573 77.166  117.400 1.00 90.69  ? 234 GLU A OE2 1 
ATOM   1824 N  N   . GLY A 1 235 ? 121.988 77.537  116.729 1.00 88.06  ? 235 GLY A N   1 
ATOM   1825 C  CA  . GLY A 1 235 ? 120.778 77.825  115.984 1.00 88.06  ? 235 GLY A CA  1 
ATOM   1826 C  C   . GLY A 1 235 ? 119.548 77.859  116.865 1.00 88.06  ? 235 GLY A C   1 
ATOM   1827 O  O   . GLY A 1 235 ? 118.640 78.661  116.642 1.00 88.06  ? 235 GLY A O   1 
ATOM   1828 N  N   . ALA A 1 236 ? 119.494 76.985  117.871 1.00 86.36  ? 236 ALA A N   1 
ATOM   1829 C  CA  . ALA A 1 236 ? 118.359 76.988  118.785 1.00 86.36  ? 236 ALA A CA  1 
ATOM   1830 C  C   . ALA A 1 236 ? 118.394 78.203  119.692 1.00 86.36  ? 236 ALA A C   1 
ATOM   1831 O  O   . ALA A 1 236 ? 117.347 78.708  120.102 1.00 86.36  ? 236 ALA A O   1 
ATOM   1832 C  CB  . ALA A 1 236 ? 118.340 75.711  119.618 1.00 86.36  ? 236 ALA A CB  1 
ATOM   1833 N  N   . ALA A 1 237 ? 119.591 78.695  120.006 1.00 84.73  ? 237 ALA A N   1 
ATOM   1834 C  CA  . ALA A 1 237 ? 119.702 79.876  120.849 1.00 84.73  ? 237 ALA A CA  1 
ATOM   1835 C  C   . ALA A 1 237 ? 119.301 81.130  120.093 1.00 84.73  ? 237 ALA A C   1 
ATOM   1836 O  O   . ALA A 1 237 ? 118.968 82.147  120.704 1.00 84.73  ? 237 ALA A O   1 
ATOM   1837 C  CB  . ALA A 1 237 ? 121.121 80.010  121.384 1.00 84.73  ? 237 ALA A CB  1 
ATOM   1838 N  N   . ALA A 1 238 ? 119.336 81.084  118.764 1.00 82.98  ? 238 ALA A N   1 
ATOM   1839 C  CA  . ALA A 1 238 ? 118.875 82.220  117.980 1.00 82.98  ? 238 ALA A CA  1 
ATOM   1840 C  C   . ALA A 1 238 ? 117.360 82.309  117.993 1.00 82.98  ? 238 ALA A C   1 
ATOM   1841 O  O   . ALA A 1 238 ? 116.792 83.396  118.134 1.00 82.98  ? 238 ALA A O   1 
ATOM   1842 C  CB  . ALA A 1 238 ? 119.392 82.109  116.550 1.00 82.98  ? 238 ALA A CB  1 
ATOM   1843 N  N   . LEU A 1 239 ? 116.688 81.172  117.843 1.00 81.85  ? 239 LEU A N   1 
ATOM   1844 C  CA  . LEU A 1 239 ? 115.234 81.149  117.860 1.00 81.85  ? 239 LEU A CA  1 
ATOM   1845 C  C   . LEU A 1 239 ? 114.677 81.369  119.256 1.00 81.85  ? 239 LEU A C   1 
ATOM   1846 O  O   . LEU A 1 239 ? 113.640 82.017  119.406 1.00 81.85  ? 239 LEU A O   1 
ATOM   1847 C  CB  . LEU A 1 239 ? 114.734 79.825  117.294 1.00 81.85  ? 239 LEU A CB  1 
ATOM   1848 C  CG  . LEU A 1 239 ? 113.232 79.639  117.142 1.00 81.85  ? 239 LEU A CG  1 
ATOM   1849 C  CD1 . LEU A 1 239 ? 112.638 80.791  116.385 1.00 81.85  ? 239 LEU A CD1 1 
ATOM   1850 C  CD2 . LEU A 1 239 ? 112.955 78.348  116.426 1.00 81.85  ? 239 LEU A CD2 1 
ATOM   1851 N  N   . GLN A 1 240 ? 115.347 80.856  120.284 1.00 82.78  ? 240 GLN A N   1 
ATOM   1852 C  CA  . GLN A 1 240 ? 114.878 81.052  121.647 1.00 82.78  ? 240 GLN A CA  1 
ATOM   1853 C  C   . GLN A 1 240 ? 115.057 82.485  122.113 1.00 82.78  ? 240 GLN A C   1 
ATOM   1854 O  O   . GLN A 1 240 ? 114.283 82.965  122.944 1.00 82.78  ? 240 GLN A O   1 
ATOM   1855 C  CB  . GLN A 1 240 ? 115.607 80.104  122.589 1.00 82.78  ? 240 GLN A CB  1 
ATOM   1856 C  CG  . GLN A 1 240 ? 115.098 78.697  122.516 1.00 82.78  ? 240 GLN A CG  1 
ATOM   1857 C  CD  . GLN A 1 240 ? 115.990 77.733  123.235 1.00 82.78  ? 240 GLN A CD  1 
ATOM   1858 O  OE1 . GLN A 1 240 ? 116.803 78.127  124.063 1.00 82.78  ? 240 GLN A OE1 1 
ATOM   1859 N  NE2 . GLN A 1 240 ? 115.850 76.459  122.923 1.00 82.78  ? 240 GLN A NE2 1 
ATOM   1860 N  N   . ARG A 1 241 ? 116.064 83.178  121.597 1.00 82.11  ? 241 ARG A N   1 
ATOM   1861 C  CA  . ARG A 1 241 ? 116.237 84.590  121.895 1.00 82.11  ? 241 ARG A CA  1 
ATOM   1862 C  C   . ARG A 1 241 ? 115.148 85.431  121.252 1.00 82.11  ? 241 ARG A C   1 
ATOM   1863 O  O   . ARG A 1 241 ? 114.741 86.453  121.812 1.00 82.11  ? 241 ARG A O   1 
ATOM   1864 C  CB  . ARG A 1 241 ? 117.623 85.034  121.426 1.00 82.11  ? 241 ARG A CB  1 
ATOM   1865 C  CG  . ARG A 1 241 ? 117.922 86.505  121.472 1.00 82.11  ? 241 ARG A CG  1 
ATOM   1866 C  CD  . ARG A 1 241 ? 119.054 86.829  120.533 1.00 82.11  ? 241 ARG A CD  1 
ATOM   1867 N  NE  . ARG A 1 241 ? 118.627 86.769  119.143 1.00 82.11  ? 241 ARG A NE  1 
ATOM   1868 C  CZ  . ARG A 1 241 ? 119.356 86.251  118.163 1.00 82.11  ? 241 ARG A CZ  1 
ATOM   1869 N  NH1 . ARG A 1 241 ? 120.548 85.742  118.425 1.00 82.11  ? 241 ARG A NH1 1 
ATOM   1870 N  NH2 . ARG A 1 241 ? 118.891 86.237  116.924 1.00 82.11  ? 241 ARG A NH2 1 
ATOM   1871 N  N   . ASP A 1 242 ? 114.631 84.997  120.107 1.00 82.50  ? 242 ASP A N   1 
ATOM   1872 C  CA  . ASP A 1 242 ? 113.603 85.764  119.419 1.00 82.50  ? 242 ASP A CA  1 
ATOM   1873 C  C   . ASP A 1 242 ? 112.222 85.509  120.000 1.00 82.50  ? 242 ASP A C   1 
ATOM   1874 O  O   . ASP A 1 242 ? 111.354 86.381  119.935 1.00 82.50  ? 242 ASP A O   1 
ATOM   1875 C  CB  . ASP A 1 242 ? 113.624 85.438  117.931 1.00 82.50  ? 242 ASP A CB  1 
ATOM   1876 C  CG  . ASP A 1 242 ? 114.708 86.192  117.195 1.00 82.50  ? 242 ASP A CG  1 
ATOM   1877 O  OD1 . ASP A 1 242 ? 114.853 87.408  117.435 1.00 82.50  ? 242 ASP A OD1 1 
ATOM   1878 O  OD2 . ASP A 1 242 ? 115.420 85.572  116.380 1.00 82.50  ? 242 ASP A OD2 1 
ATOM   1879 N  N   . LEU A 1 243 ? 112.003 84.327  120.574 1.00 78.25  ? 243 LEU A N   1 
ATOM   1880 C  CA  . LEU A 1 243 ? 110.728 84.042  121.215 1.00 78.25  ? 243 LEU A CA  1 
ATOM   1881 C  C   . LEU A 1 243 ? 110.578 84.822  122.507 1.00 78.25  ? 243 LEU A C   1 
ATOM   1882 O  O   . LEU A 1 243 ? 109.463 85.178  122.898 1.00 78.25  ? 243 LEU A O   1 
ATOM   1883 C  CB  . LEU A 1 243 ? 110.607 82.551  121.488 1.00 78.25  ? 243 LEU A CB  1 
ATOM   1884 C  CG  . LEU A 1 243 ? 110.449 81.634  120.287 1.00 78.25  ? 243 LEU A CG  1 
ATOM   1885 C  CD1 . LEU A 1 243 ? 110.772 80.221  120.689 1.00 78.25  ? 243 LEU A CD1 1 
ATOM   1886 C  CD2 . LEU A 1 243 ? 109.048 81.718  119.760 1.00 78.25  ? 243 LEU A CD2 1 
ATOM   1887 N  N   . ARG A 1 244 ? 111.687 85.093  123.190 1.00 76.69  ? 244 ARG A N   1 
ATOM   1888 C  CA  . ARG A 1 244 ? 111.615 85.839  124.438 1.00 76.69  ? 244 ARG A CA  1 
ATOM   1889 C  C   . ARG A 1 244 ? 111.373 87.314  124.178 1.00 76.69  ? 244 ARG A C   1 
ATOM   1890 O  O   . ARG A 1 244 ? 110.693 87.987  124.957 1.00 76.69  ? 244 ARG A O   1 
ATOM   1891 C  CB  . ARG A 1 244 ? 112.893 85.636  125.241 1.00 76.69  ? 244 ARG A CB  1 
ATOM   1892 C  CG  . ARG A 1 244 ? 113.042 84.249  125.794 1.00 76.69  ? 244 ARG A CG  1 
ATOM   1893 C  CD  . ARG A 1 244 ? 113.819 84.262  127.079 1.00 76.69  ? 244 ARG A CD  1 
ATOM   1894 N  NE  . ARG A 1 244 ? 113.665 83.016  127.814 1.00 76.69  ? 244 ARG A NE  1 
ATOM   1895 C  CZ  . ARG A 1 244 ? 114.439 81.954  127.643 1.00 76.69  ? 244 ARG A CZ  1 
ATOM   1896 N  NH1 . ARG A 1 244 ? 115.424 81.987  126.758 1.00 76.69  ? 244 ARG A NH1 1 
ATOM   1897 N  NH2 . ARG A 1 244 ? 114.231 80.861  128.357 1.00 76.69  ? 244 ARG A NH2 1 
ATOM   1898 N  N   . LEU A 1 245 ? 111.925 87.839  123.088 1.00 75.00  ? 245 LEU A N   1 
ATOM   1899 C  CA  . LEU A 1 245 ? 111.689 89.234  122.747 1.00 75.00  ? 245 LEU A CA  1 
ATOM   1900 C  C   . LEU A 1 245 ? 110.280 89.436  122.210 1.00 75.00  ? 245 LEU A C   1 
ATOM   1901 O  O   . LEU A 1 245 ? 109.672 90.488  122.426 1.00 75.00  ? 245 LEU A O   1 
ATOM   1902 C  CB  . LEU A 1 245 ? 112.731 89.706  121.737 1.00 75.00  ? 245 LEU A CB  1 
ATOM   1903 C  CG  . LEU A 1 245 ? 112.636 91.142  121.238 1.00 75.00  ? 245 LEU A CG  1 
ATOM   1904 C  CD1 . LEU A 1 245 ? 112.747 92.094  122.390 1.00 75.00  ? 245 LEU A CD1 1 
ATOM   1905 C  CD2 . LEU A 1 245 ? 113.705 91.416  120.221 1.00 75.00  ? 245 LEU A CD2 1 
ATOM   1906 N  N   . ALA A 1 246 ? 109.733 88.435  121.524 1.00 74.82  ? 246 ALA A N   1 
ATOM   1907 C  CA  . ALA A 1 246 ? 108.363 88.552  121.046 1.00 74.82  ? 246 ALA A CA  1 
ATOM   1908 C  C   . ALA A 1 246 ? 107.366 88.381  122.178 1.00 74.82  ? 246 ALA A C   1 
ATOM   1909 O  O   . ALA A 1 246 ? 106.258 88.918  122.118 1.00 74.82  ? 246 ALA A O   1 
ATOM   1910 C  CB  . ALA A 1 246 ? 108.098 87.534  119.953 1.00 74.82  ? 246 ALA A CB  1 
ATOM   1911 N  N   . LYS A 1 247 ? 107.727 87.623  123.207 1.00 75.77  ? 247 LYS A N   1 
ATOM   1912 C  CA  . LYS A 1 247 ? 106.877 87.546  124.386 1.00 75.77  ? 247 LYS A CA  1 
ATOM   1913 C  C   . LYS A 1 247 ? 106.951 88.838  125.179 1.00 75.77  ? 247 LYS A C   1 
ATOM   1914 O  O   . LYS A 1 247 ? 105.960 89.269  125.777 1.00 75.77  ? 247 LYS A O   1 
ATOM   1915 C  CB  . LYS A 1 247 ? 107.291 86.355  125.246 1.00 75.77  ? 247 LYS A CB  1 
ATOM   1916 C  CG  . LYS A 1 247 ? 106.510 86.182  126.530 1.00 75.77  ? 247 LYS A CG  1 
ATOM   1917 C  CD  . LYS A 1 247 ? 105.028 86.103  126.261 1.00 75.77  ? 247 LYS A CD  1 
ATOM   1918 C  CE  . LYS A 1 247 ? 104.242 85.927  127.541 1.00 75.77  ? 247 LYS A CE  1 
ATOM   1919 N  NZ  . LYS A 1 247 ? 102.790 85.810  127.266 1.00 75.77  ? 247 LYS A NZ  1 
ATOM   1920 N  N   . ARG A 1 248 ? 108.115 89.482  125.167 1.00 73.29  ? 248 ARG A N   1 
ATOM   1921 C  CA  . ARG A 1 248 ? 108.302 90.709  125.926 1.00 73.29  ? 248 ARG A CA  1 
ATOM   1922 C  C   . ARG A 1 248 ? 107.522 91.859  125.314 1.00 73.29  ? 248 ARG A C   1 
ATOM   1923 O  O   . ARG A 1 248 ? 107.061 92.753  126.028 1.00 73.29  ? 248 ARG A O   1 
ATOM   1924 C  CB  . ARG A 1 248 ? 109.788 91.042  125.990 1.00 73.29  ? 248 ARG A CB  1 
ATOM   1925 C  CG  . ARG A 1 248 ? 110.154 92.110  126.977 1.00 73.29  ? 248 ARG A CG  1 
ATOM   1926 C  CD  . ARG A 1 248 ? 111.579 92.539  126.779 1.00 73.29  ? 248 ARG A CD  1 
ATOM   1927 N  NE  . ARG A 1 248 ? 111.880 93.750  127.523 1.00 73.29  ? 248 ARG A NE  1 
ATOM   1928 C  CZ  . ARG A 1 248 ? 113.020 94.416  127.423 1.00 73.29  ? 248 ARG A CZ  1 
ATOM   1929 N  NH1 . ARG A 1 248 ? 113.968 93.983  126.611 1.00 73.29  ? 248 ARG A NH1 1 
ATOM   1930 N  NH2 . ARG A 1 248 ? 113.211 95.511  128.136 1.00 73.29  ? 248 ARG A NH2 1 
ATOM   1931 N  N   . LEU A 1 249 ? 107.343 91.844  124.000 1.00 71.90  ? 249 LEU A N   1 
ATOM   1932 C  CA  . LEU A 1 249 ? 106.673 92.940  123.322 1.00 71.90  ? 249 LEU A CA  1 
ATOM   1933 C  C   . LEU A 1 249 ? 105.207 92.667  123.034 1.00 71.90  ? 249 LEU A C   1 
ATOM   1934 O  O   . LEU A 1 249 ? 104.527 93.547  122.506 1.00 71.90  ? 249 LEU A O   1 
ATOM   1935 C  CB  . LEU A 1 249 ? 107.401 93.268  122.022 1.00 71.90  ? 249 LEU A CB  1 
ATOM   1936 C  CG  . LEU A 1 249 ? 108.841 93.734  122.196 1.00 71.90  ? 249 LEU A CG  1 
ATOM   1937 C  CD1 . LEU A 1 249 ? 109.428 94.122  120.870 1.00 71.90  ? 249 LEU A CD1 1 
ATOM   1938 C  CD2 . LEU A 1 249 ? 108.904 94.891  123.149 1.00 71.90  ? 249 LEU A CD2 1 
ATOM   1939 N  N   . GLY A 1 250 ? 104.703 91.485  123.360 1.00 72.41  ? 250 GLY A N   1 
ATOM   1940 C  CA  . GLY A 1 250 ? 103.293 91.200  123.235 1.00 72.41  ? 250 GLY A CA  1 
ATOM   1941 C  C   . GLY A 1 250 ? 102.875 90.485  121.975 1.00 72.41  ? 250 GLY A C   1 
ATOM   1942 O  O   . GLY A 1 250 ? 101.673 90.331  121.748 1.00 72.41  ? 250 GLY A O   1 
ATOM   1943 N  N   . PHE A 1 251 ? 103.818 90.038  121.156 1.00 71.14  ? 251 PHE A N   1 
ATOM   1944 C  CA  . PHE A 1 251 ? 103.477 89.417  119.889 1.00 71.14  ? 251 PHE A CA  1 
ATOM   1945 C  C   . PHE A 1 251 ? 102.953 88.010  120.105 1.00 71.14  ? 251 PHE A C   1 
ATOM   1946 O  O   . PHE A 1 251 ? 103.194 87.388  121.139 1.00 71.14  ? 251 PHE A O   1 
ATOM   1947 C  CB  . PHE A 1 251 ? 104.691 89.384  118.974 1.00 71.14  ? 251 PHE A CB  1 
ATOM   1948 C  CG  . PHE A 1 251 ? 105.037 90.709  118.395 1.00 71.14  ? 251 PHE A CG  1 
ATOM   1949 C  CD1 . PHE A 1 251 ? 104.526 91.095  117.178 1.00 71.14  ? 251 PHE A CD1 1 
ATOM   1950 C  CD2 . PHE A 1 251 ? 105.865 91.575  119.069 1.00 71.14  ? 251 PHE A CD2 1 
ATOM   1951 C  CE1 . PHE A 1 251 ? 104.838 92.317  116.645 1.00 71.14  ? 251 PHE A CE1 1 
ATOM   1952 C  CE2 . PHE A 1 251 ? 106.175 92.796  118.541 1.00 71.14  ? 251 PHE A CE2 1 
ATOM   1953 C  CZ  . PHE A 1 251 ? 105.657 93.167  117.331 1.00 71.14  ? 251 PHE A CZ  1 
ATOM   1954 N  N   . ARG A 1 252 ? 102.221 87.508  119.115 1.00 75.15  ? 252 ARG A N   1 
ATOM   1955 C  CA  . ARG A 1 252 ? 101.630 86.182  119.201 1.00 75.15  ? 252 ARG A CA  1 
ATOM   1956 C  C   . ARG A 1 252 ? 102.276 85.172  118.275 1.00 75.15  ? 252 ARG A C   1 
ATOM   1957 O  O   . ARG A 1 252 ? 102.191 83.973  118.537 1.00 75.15  ? 252 ARG A O   1 
ATOM   1958 C  CB  . ARG A 1 252 ? 100.137 86.244  118.891 1.00 75.15  ? 252 ARG A CB  1 
ATOM   1959 C  CG  . ARG A 1 252 ? 99.432  87.397  119.541 1.00 75.15  ? 252 ARG A CG  1 
ATOM   1960 C  CD  . ARG A 1 252 ? 98.039  87.002  119.956 1.00 75.15  ? 252 ARG A CD  1 
ATOM   1961 N  NE  . ARG A 1 252 ? 97.344  86.276  118.901 1.00 75.15  ? 252 ARG A NE  1 
ATOM   1962 C  CZ  . ARG A 1 252 ? 96.625  86.855  117.947 1.00 75.15  ? 252 ARG A CZ  1 
ATOM   1963 N  NH1 . ARG A 1 252 ? 96.509  88.173  117.908 1.00 75.15  ? 252 ARG A NH1 1 
ATOM   1964 N  NH2 . ARG A 1 252 ? 96.023  86.115  117.029 1.00 75.15  ? 252 ARG A NH2 1 
ATOM   1965 N  N   . PHE A 1 253 ? 102.909 85.614  117.200 1.00 73.12  ? 253 PHE A N   1 
ATOM   1966 C  CA  . PHE A 1 253 ? 103.525 84.715  116.242 1.00 73.12  ? 253 PHE A CA  1 
ATOM   1967 C  C   . PHE A 1 253 ? 104.976 85.108  116.034 1.00 73.12  ? 253 PHE A C   1 
ATOM   1968 O  O   . PHE A 1 253 ? 105.319 86.290  116.094 1.00 73.12  ? 253 PHE A O   1 
ATOM   1969 C  CB  . PHE A 1 253 ? 102.798 84.737  114.900 1.00 73.12  ? 253 PHE A CB  1 
ATOM   1970 C  CG  . PHE A 1 253 ? 101.311 84.652  115.008 1.00 73.12  ? 253 PHE A CG  1 
ATOM   1971 C  CD1 . PHE A 1 253 ? 100.524 85.734  114.674 1.00 73.12  ? 253 PHE A CD1 1 
ATOM   1972 C  CD2 . PHE A 1 253 ? 100.698 83.489  115.420 1.00 73.12  ? 253 PHE A CD2 1 
ATOM   1973 C  CE1 . PHE A 1 253 ? 99.161  85.663  114.767 1.00 73.12  ? 253 PHE A CE1 1 
ATOM   1974 C  CE2 . PHE A 1 253 ? 99.333  83.414  115.510 1.00 73.12  ? 253 PHE A CE2 1 
ATOM   1975 C  CZ  . PHE A 1 253 ? 98.565  84.502  115.184 1.00 73.12  ? 253 PHE A CZ  1 
ATOM   1976 N  N   . VAL A 1 254 ? 105.823 84.112  115.789 1.00 74.12  ? 254 VAL A N   1 
ATOM   1977 C  CA  . VAL A 1 254 ? 107.215 84.318  115.412 1.00 74.12  ? 254 VAL A CA  1 
ATOM   1978 C  C   . VAL A 1 254 ? 107.441 83.588  114.104 1.00 74.12  ? 254 VAL A C   1 
ATOM   1979 O  O   . VAL A 1 254 ? 107.138 82.396  113.997 1.00 74.12  ? 254 VAL A O   1 
ATOM   1980 C  CB  . VAL A 1 254 ? 108.188 83.819  116.490 1.00 74.12  ? 254 VAL A CB  1 
ATOM   1981 C  CG1 . VAL A 1 254 ? 109.593 83.752  115.962 1.00 74.12  ? 254 VAL A CG1 1 
ATOM   1982 C  CG2 . VAL A 1 254 ? 108.174 84.733  117.638 1.00 74.12  ? 254 VAL A CG2 1 
ATOM   1983 N  N   . ARG A 1 255 ? 107.961 84.298  113.109 1.00 75.35  ? 255 ARG A N   1 
ATOM   1984 C  CA  . ARG A 1 255 ? 108.271 83.686  111.830 1.00 75.35  ? 255 ARG A CA  1 
ATOM   1985 C  C   . ARG A 1 255 ? 109.774 83.554  111.678 1.00 75.35  ? 255 ARG A C   1 
ATOM   1986 O  O   . ARG A 1 255 ? 110.444 84.557  111.405 1.00 75.35  ? 255 ARG A O   1 
ATOM   1987 C  CB  . ARG A 1 255 ? 107.692 84.511  110.688 1.00 75.35  ? 255 ARG A CB  1 
ATOM   1988 C  CG  . ARG A 1 255 ? 107.947 83.942  109.318 1.00 75.35  ? 255 ARG A CG  1 
ATOM   1989 C  CD  . ARG A 1 255 ? 108.448 85.003  108.374 1.00 75.35  ? 255 ARG A CD  1 
ATOM   1990 N  NE  . ARG A 1 255 ? 109.792 85.433  108.722 1.00 75.35  ? 255 ARG A NE  1 
ATOM   1991 C  CZ  . ARG A 1 255 ? 110.426 86.436  108.133 1.00 75.35  ? 255 ARG A CZ  1 
ATOM   1992 N  NH1 . ARG A 1 255 ? 109.835 87.111  107.165 1.00 75.35  ? 255 ARG A NH1 1 
ATOM   1993 N  NH2 . ARG A 1 255 ? 111.648 86.764  108.512 1.00 75.35  ? 255 ARG A NH2 1 
ATOM   1994 N  N   . PRO A 1 256 ? 110.348 82.373  111.859 1.00 75.16  ? 256 PRO A N   1 
ATOM   1995 C  CA  . PRO A 1 256 ? 111.785 82.216  111.627 1.00 75.16  ? 256 PRO A CA  1 
ATOM   1996 C  C   . PRO A 1 256 ? 112.115 81.920  110.176 1.00 75.16  ? 256 PRO A C   1 
ATOM   1997 O  O   . PRO A 1 256 ? 111.483 81.073  109.542 1.00 75.16  ? 256 PRO A O   1 
ATOM   1998 C  CB  . PRO A 1 256 ? 112.153 81.045  112.538 1.00 75.16  ? 256 PRO A CB  1 
ATOM   1999 C  CG  . PRO A 1 256 ? 110.925 80.264  112.652 1.00 75.16  ? 256 PRO A CG  1 
ATOM   2000 C  CD  . PRO A 1 256 ? 109.764 81.184  112.493 1.00 75.16  ? 256 PRO A CD  1 
ATOM   2001 N  N   . LYS A 1 257 ? 113.099 82.621  109.638 1.00 78.07  ? 257 LYS A N   1 
ATOM   2002 C  CA  . LYS A 1 257 ? 113.539 82.436  108.263 1.00 78.07  ? 257 LYS A CA  1 
ATOM   2003 C  C   . LYS A 1 257 ? 114.884 81.721  108.286 1.00 78.07  ? 257 LYS A C   1 
ATOM   2004 O  O   . LYS A 1 257 ? 115.914 82.338  108.554 1.00 78.07  ? 257 LYS A O   1 
ATOM   2005 C  CB  . LYS A 1 257 ? 113.633 83.779  107.549 1.00 78.07  ? 257 LYS A CB  1 
ATOM   2006 C  CG  . LYS A 1 257 ? 114.053 83.684  106.110 1.00 78.07  ? 257 LYS A CG  1 
ATOM   2007 C  CD  . LYS A 1 257 ? 113.002 82.996  105.274 1.00 78.07  ? 257 LYS A CD  1 
ATOM   2008 C  CE  . LYS A 1 257 ? 111.895 83.949  104.911 1.00 78.07  ? 257 LYS A CE  1 
ATOM   2009 N  NZ  . LYS A 1 257 ? 112.389 84.988  103.974 1.00 78.07  ? 257 LYS A NZ  1 
ATOM   2010 N  N   . ILE A 1 258 ? 114.868 80.424  108.013 1.00 81.03  ? 258 ILE A N   1 
ATOM   2011 C  CA  . ILE A 1 258 ? 116.060 79.588  108.072 1.00 81.03  ? 258 ILE A CA  1 
ATOM   2012 C  C   . ILE A 1 258 ? 116.832 79.732  106.765 1.00 81.03  ? 258 ILE A C   1 
ATOM   2013 O  O   . ILE A 1 258 ? 116.263 80.054  105.720 1.00 81.03  ? 258 ILE A O   1 
ATOM   2014 C  CB  . ILE A 1 258 ? 115.656 78.125  108.366 1.00 81.03  ? 258 ILE A CB  1 
ATOM   2015 C  CG1 . ILE A 1 258 ? 116.849 77.225  108.695 1.00 81.03  ? 258 ILE A CG1 1 
ATOM   2016 C  CG2 . ILE A 1 258 ? 114.853 77.540  107.222 1.00 81.03  ? 258 ILE A CG2 1 
ATOM   2017 C  CD1 . ILE A 1 258 ? 117.417 77.426  110.046 1.00 81.03  ? 258 ILE A CD1 1 
ATOM   2018 N  N   . GLY A 1 259 ? 118.149 79.541  106.820 1.00 84.75  ? 259 GLY A N   1 
ATOM   2019 C  CA  . GLY A 1 259 ? 118.948 79.564  105.618 1.00 84.75  ? 259 GLY A CA  1 
ATOM   2020 C  C   . GLY A 1 259 ? 118.804 78.302  104.792 1.00 84.75  ? 259 GLY A C   1 
ATOM   2021 O  O   . GLY A 1 259 ? 118.407 77.248  105.275 1.00 84.75  ? 259 GLY A O   1 
ATOM   2022 N  N   . VAL A 1 260 ? 119.150 78.418  103.515 1.00 89.06  ? 260 VAL A N   1 
ATOM   2023 C  CA  . VAL A 1 260 ? 118.938 77.352  102.548 1.00 89.06  ? 260 VAL A CA  1 
ATOM   2024 C  C   . VAL A 1 260 ? 120.278 76.772  102.126 1.00 89.06  ? 260 VAL A C   1 
ATOM   2025 O  O   . VAL A 1 260 ? 121.335 77.379  102.314 1.00 89.06  ? 260 VAL A O   1 
ATOM   2026 C  CB  . VAL A 1 260 ? 118.150 77.853  101.326 1.00 89.06  ? 260 VAL A CB  1 
ATOM   2027 C  CG1 . VAL A 1 260 ? 116.801 78.351  101.760 1.00 89.06  ? 260 VAL A CG1 1 
ATOM   2028 C  CG2 . VAL A 1 260 ? 118.911 78.952  100.631 1.00 89.06  ? 260 VAL A CG2 1 
ATOM   2029 N  N   . VAL A 1 261 ? 120.230 75.566  101.561 1.00 93.95  ? 261 VAL A N   1 
ATOM   2030 C  CA  . VAL A 1 261 ? 121.422 74.837  101.152 1.00 93.95  ? 261 VAL A CA  1 
ATOM   2031 C  C   . VAL A 1 261 ? 121.377 74.426  99.687  1.00 93.95  ? 261 VAL A C   1 
ATOM   2032 O  O   . VAL A 1 261 ? 122.275 73.728  99.221  1.00 93.95  ? 261 VAL A O   1 
ATOM   2033 C  CB  . VAL A 1 261 ? 121.664 73.600  102.038 1.00 93.95  ? 261 VAL A CB  1 
ATOM   2034 C  CG1 . VAL A 1 261 ? 121.869 73.986  103.476 1.00 93.95  ? 261 VAL A CG1 1 
ATOM   2035 C  CG2 . VAL A 1 261 ? 120.505 72.641  101.914 1.00 93.95  ? 261 VAL A CG2 1 
ATOM   2036 N  N   . SER A 1 262 ? 120.353 74.835  98.947  1.00 98.76  ? 262 SER A N   1 
ATOM   2037 C  CA  . SER A 1 262 ? 120.226 74.406  97.562  1.00 98.76  ? 262 SER A CA  1 
ATOM   2038 C  C   . SER A 1 262 ? 119.459 75.458  96.782  1.00 98.76  ? 262 SER A C   1 
ATOM   2039 O  O   . SER A 1 262 ? 118.975 76.444  97.336  1.00 98.76  ? 262 SER A O   1 
ATOM   2040 C  CB  . SER A 1 262 ? 119.522 73.055  97.459  1.00 98.76  ? 262 SER A CB  1 
ATOM   2041 O  OG  . SER A 1 262 ? 118.122 73.220  97.570  1.00 98.76  ? 262 SER A OG  1 
ATOM   2042 N  N   . SER A 1 263 ? 119.343 75.221  95.475  1.00 103.12 ? 263 SER A N   1 
ATOM   2043 C  CA  . SER A 1 263 ? 118.645 76.154  94.602  1.00 103.12 ? 263 SER A CA  1 
ATOM   2044 C  C   . SER A 1 263 ? 117.134 76.070  94.747  1.00 103.12 ? 263 SER A C   1 
ATOM   2045 O  O   . SER A 1 263 ? 116.435 77.017  94.377  1.00 103.12 ? 263 SER A O   1 
ATOM   2046 C  CB  . SER A 1 263 ? 119.034 75.902  93.149  1.00 103.12 ? 263 SER A CB  1 
ATOM   2047 O  OG  . SER A 1 263 ? 118.374 74.757  92.640  1.00 103.12 ? 263 SER A OG  1 
ATOM   2048 N  N   . ASP A 1 264 ? 116.613 74.968  95.280  1.00 103.28 ? 264 ASP A N   1 
ATOM   2049 C  CA  . ASP A 1 264 ? 115.180 74.780  95.439  1.00 103.28 ? 264 ASP A CA  1 
ATOM   2050 C  C   . ASP A 1 264 ? 114.663 75.332  96.757  1.00 103.28 ? 264 ASP A C   1 
ATOM   2051 O  O   . ASP A 1 264 ? 113.534 75.013  97.145  1.00 103.28 ? 264 ASP A O   1 
ATOM   2052 C  CB  . ASP A 1 264 ? 114.833 73.298  95.325  1.00 103.28 ? 264 ASP A CB  1 
ATOM   2053 C  CG  . ASP A 1 264 ? 115.036 72.763  93.928  1.00 103.28 ? 264 ASP A CG  1 
ATOM   2054 O  OD1 . ASP A 1 264 ? 114.870 73.540  92.965  1.00 103.28 ? 264 ASP A OD1 1 
ATOM   2055 O  OD2 . ASP A 1 264 ? 115.369 71.569  93.790  1.00 103.28 ? 264 ASP A OD2 1 
ATOM   2056 N  N   . LEU A 1 265 ? 115.474 76.152  97.438  1.00 98.18  ? 265 LEU A N   1 
ATOM   2057 C  CA  . LEU A 1 265 ? 115.204 76.697  98.773  1.00 98.18  ? 265 LEU A CA  1 
ATOM   2058 C  C   . LEU A 1 265 ? 114.919 75.590  99.783  1.00 98.18  ? 265 LEU A C   1 
ATOM   2059 O  O   . LEU A 1 265 ? 114.046 75.716  100.641 1.00 98.18  ? 265 LEU A O   1 
ATOM   2060 C  CB  . LEU A 1 265 ? 114.069 77.723  98.753  1.00 98.18  ? 265 LEU A CB  1 
ATOM   2061 C  CG  . LEU A 1 265 ? 114.177 78.902  97.789  1.00 98.18  ? 265 LEU A CG  1 
ATOM   2062 C  CD1 . LEU A 1 265 ? 113.126 79.927  98.144  1.00 98.18  ? 265 LEU A CD1 1 
ATOM   2063 C  CD2 . LEU A 1 265 ? 115.553 79.526  97.822  1.00 98.18  ? 265 LEU A CD2 1 
ATOM   2064 N  N   . ILE A 1 266 ? 115.653 74.490  99.661  1.00 97.38  ? 266 ILE A N   1 
ATOM   2065 C  CA  . ILE A 1 266 ? 115.589 73.439  100.677 1.00 97.38  ? 266 ILE A CA  1 
ATOM   2066 C  C   . ILE A 1 266 ? 116.216 73.969  101.954 1.00 97.38  ? 266 ILE A C   1 
ATOM   2067 O  O   . ILE A 1 266 ? 117.334 74.515  101.904 1.00 97.38  ? 266 ILE A O   1 
ATOM   2068 C  CB  . ILE A 1 266 ? 116.318 72.177  100.188 1.00 97.38  ? 266 ILE A CB  1 
ATOM   2069 C  CG1 . ILE A 1 266 ? 115.538 71.520  99.052  1.00 97.38  ? 266 ILE A CG1 1 
ATOM   2070 C  CG2 . ILE A 1 266 ? 116.526 71.195  101.321 1.00 97.38  ? 266 ILE A CG2 1 
ATOM   2071 C  CD1 . ILE A 1 266 ? 114.097 71.220  99.390  1.00 97.38  ? 266 ILE A CD1 1 
ATOM   2072 N  N   . PRO A 1 267 ? 115.544 73.878  103.101 1.00 92.85  ? 267 PRO A N   1 
ATOM   2073 C  CA  . PRO A 1 267 ? 116.093 74.454  104.331 1.00 92.85  ? 267 PRO A CA  1 
ATOM   2074 C  C   . PRO A 1 267 ? 117.339 73.726  104.802 1.00 92.85  ? 267 PRO A C   1 
ATOM   2075 O  O   . PRO A 1 267 ? 117.619 72.599  104.391 1.00 92.85  ? 267 PRO A O   1 
ATOM   2076 C  CB  . PRO A 1 267 ? 114.949 74.293  105.336 1.00 92.85  ? 267 PRO A CB  1 
ATOM   2077 C  CG  . PRO A 1 267 ? 113.739 74.097  104.515 1.00 92.85  ? 267 PRO A CG  1 
ATOM   2078 C  CD  . PRO A 1 267 ? 114.180 73.372  103.296 1.00 92.85  ? 267 PRO A CD  1 
ATOM   2079 N  N   . HIS A 1 268 ? 118.105 74.416  105.640 1.00 89.45  ? 268 HIS A N   1 
ATOM   2080 C  CA  . HIS A 1 268 ? 119.295 73.844  106.242 1.00 89.45  ? 268 HIS A CA  1 
ATOM   2081 C  C   . HIS A 1 268 ? 118.898 72.663  107.124 1.00 89.45  ? 268 HIS A C   1 
ATOM   2082 O  O   . HIS A 1 268 ? 117.837 72.696  107.748 1.00 89.45  ? 268 HIS A O   1 
ATOM   2083 C  CB  . HIS A 1 268 ? 120.015 74.909  107.062 1.00 89.45  ? 268 HIS A CB  1 
ATOM   2084 C  CG  . HIS A 1 268 ? 121.452 74.606  107.333 1.00 89.45  ? 268 HIS A CG  1 
ATOM   2085 N  ND1 . HIS A 1 268 ? 121.856 73.742  108.324 1.00 89.45  ? 268 HIS A ND1 1 
ATOM   2086 C  CD2 . HIS A 1 268 ? 122.583 75.074  106.760 1.00 89.45  ? 268 HIS A CD2 1 
ATOM   2087 C  CE1 . HIS A 1 268 ? 123.174 73.674  108.338 1.00 89.45  ? 268 HIS A CE1 1 
ATOM   2088 N  NE2 . HIS A 1 268 ? 123.639 74.474  107.398 1.00 89.45  ? 268 HIS A NE2 1 
ATOM   2089 N  N   . PRO A 1 269 ? 119.704 71.596  107.164 1.00 89.29  ? 269 PRO A N   1 
ATOM   2090 C  CA  . PRO A 1 269 ? 119.288 70.379  107.884 1.00 89.29  ? 269 PRO A CA  1 
ATOM   2091 C  C   . PRO A 1 269 ? 119.115 70.538  109.383 1.00 89.29  ? 269 PRO A C   1 
ATOM   2092 O  O   . PRO A 1 269 ? 118.478 69.687  110.012 1.00 89.29  ? 269 PRO A O   1 
ATOM   2093 C  CB  . PRO A 1 269 ? 120.419 69.397  107.567 1.00 89.29  ? 269 PRO A CB  1 
ATOM   2094 C  CG  . PRO A 1 269 ? 120.931 69.841  106.270 1.00 89.29  ? 269 PRO A CG  1 
ATOM   2095 C  CD  . PRO A 1 269 ? 120.835 71.327  106.262 1.00 89.29  ? 269 PRO A CD  1 
ATOM   2096 N  N   . ILE A 1 270 ? 119.636 71.611  109.978 1.00 89.17  ? 270 ILE A N   1 
ATOM   2097 C  CA  . ILE A 1 270 ? 119.511 71.789  111.415 1.00 89.17  ? 270 ILE A CA  1 
ATOM   2098 C  C   . ILE A 1 270 ? 118.134 72.279  111.831 1.00 89.17  ? 270 ILE A C   1 
ATOM   2099 O  O   . ILE A 1 270 ? 117.866 72.352  113.032 1.00 89.17  ? 270 ILE A O   1 
ATOM   2100 C  CB  . ILE A 1 270 ? 120.581 72.767  111.932 1.00 89.17  ? 270 ILE A CB  1 
ATOM   2101 C  CG1 . ILE A 1 270 ? 120.284 74.183  111.445 1.00 89.17  ? 270 ILE A CG1 1 
ATOM   2102 C  CG2 . ILE A 1 270 ? 121.954 72.336  111.486 1.00 89.17  ? 270 ILE A CG2 1 
ATOM   2103 C  CD1 . ILE A 1 270 ? 121.119 75.235  112.099 1.00 89.17  ? 270 ILE A CD1 1 
ATOM   2104 N  N   . TRP A 1 271 ? 117.250 72.607  110.878 1.00 90.89  ? 271 TRP A N   1 
ATOM   2105 C  CA  . TRP A 1 271 ? 116.024 73.336  111.205 1.00 90.89  ? 271 TRP A CA  1 
ATOM   2106 C  C   . TRP A 1 271 ? 115.058 72.489  112.019 1.00 90.89  ? 271 TRP A C   1 
ATOM   2107 O  O   . TRP A 1 271 ? 114.334 73.011  112.869 1.00 90.89  ? 271 TRP A O   1 
ATOM   2108 C  CB  . TRP A 1 271 ? 115.344 73.849  109.927 1.00 90.89  ? 271 TRP A CB  1 
ATOM   2109 C  CG  . TRP A 1 271 ? 114.486 72.838  109.199 1.00 90.89  ? 271 TRP A CG  1 
ATOM   2110 C  CD1 . TRP A 1 271 ? 114.878 72.014  108.190 1.00 90.89  ? 271 TRP A CD1 1 
ATOM   2111 C  CD2 . TRP A 1 271 ? 113.099 72.557  109.424 1.00 90.89  ? 271 TRP A CD2 1 
ATOM   2112 N  NE1 . TRP A 1 271 ? 113.832 71.229  107.779 1.00 90.89  ? 271 TRP A NE1 1 
ATOM   2113 C  CE2 . TRP A 1 271 ? 112.729 71.540  108.526 1.00 90.89  ? 271 TRP A CE2 1 
ATOM   2114 C  CE3 . TRP A 1 271 ? 112.143 73.051  110.312 1.00 90.89  ? 271 TRP A CE3 1 
ATOM   2115 C  CZ2 . TRP A 1 271 ? 111.444 71.020  108.480 1.00 90.89  ? 271 TRP A CZ2 1 
ATOM   2116 C  CZ3 . TRP A 1 271 ? 110.873 72.532  110.268 1.00 90.89  ? 271 TRP A CZ3 1 
ATOM   2117 C  CH2 . TRP A 1 271 ? 110.534 71.522  109.363 1.00 90.89  ? 271 TRP A CH2 1 
ATOM   2118 N  N   . THR A 1 272 ? 115.037 71.182  111.787 1.00 91.23  ? 272 THR A N   1 
ATOM   2119 C  CA  . THR A 1 272 ? 114.011 70.364  112.416 1.00 91.23  ? 272 THR A CA  1 
ATOM   2120 C  C   . THR A 1 272 ? 114.390 70.012  113.844 1.00 91.23  ? 272 THR A C   1 
ATOM   2121 O  O   . THR A 1 272 ? 113.546 69.569  114.625 1.00 91.23  ? 272 THR A O   1 
ATOM   2122 C  CB  . THR A 1 272 ? 113.743 69.112  111.585 1.00 91.23  ? 272 THR A CB  1 
ATOM   2123 O  OG1 . THR A 1 272 ? 112.675 68.367  112.178 1.00 91.23  ? 272 THR A OG1 1 
ATOM   2124 C  CG2 . THR A 1 272 ? 114.967 68.250  111.495 1.00 91.23  ? 272 THR A CG2 1 
ATOM   2125 N  N   . GLU A 1 273 ? 115.655 70.201  114.212 1.00 90.97  ? 273 GLU A N   1 
ATOM   2126 C  CA  . GLU A 1 273 ? 116.022 70.017  115.610 1.00 90.97  ? 273 GLU A CA  1 
ATOM   2127 C  C   . GLU A 1 273 ? 116.260 71.350  116.307 1.00 90.97  ? 273 GLU A C   1 
ATOM   2128 O  O   . GLU A 1 273 ? 116.366 71.399  117.535 1.00 90.97  ? 273 GLU A O   1 
ATOM   2129 C  CB  . GLU A 1 273 ? 117.239 69.105  115.730 1.00 90.97  ? 273 GLU A CB  1 
ATOM   2130 C  CG  . GLU A 1 273 ? 118.435 69.549  114.947 1.00 90.97  ? 273 GLU A CG  1 
ATOM   2131 C  CD  . GLU A 1 273 ? 118.624 68.752  113.677 1.00 90.97  ? 273 GLU A CD  1 
ATOM   2132 O  OE1 . GLU A 1 273 ? 117.689 68.033  113.282 1.00 90.97  ? 273 GLU A OE1 1 
ATOM   2133 O  OE2 . GLU A 1 273 ? 119.714 68.835  113.076 1.00 90.97  ? 273 GLU A OE2 1 
ATOM   2134 N  N   . VAL A 1 274 ? 116.348 72.440  115.547 1.00 88.07  ? 274 VAL A N   1 
ATOM   2135 C  CA  . VAL A 1 274 ? 116.315 73.769  116.154 1.00 88.07  ? 274 VAL A CA  1 
ATOM   2136 C  C   . VAL A 1 274 ? 114.900 74.098  116.607 1.00 88.07  ? 274 VAL A C   1 
ATOM   2137 O  O   . VAL A 1 274 ? 114.679 74.599  117.716 1.00 88.07  ? 274 VAL A O   1 
ATOM   2138 C  CB  . VAL A 1 274 ? 116.866 74.818  115.170 1.00 88.07  ? 274 VAL A CB  1 
ATOM   2139 C  CG1 . VAL A 1 274 ? 116.403 76.211  115.517 1.00 88.07  ? 274 VAL A CG1 1 
ATOM   2140 C  CG2 . VAL A 1 274 ? 118.362 74.785  115.177 1.00 88.07  ? 274 VAL A CG2 1 
ATOM   2141 N  N   . VAL A 1 275 ? 113.916 73.781  115.765 1.00 88.80  ? 275 VAL A N   1 
ATOM   2142 C  CA  . VAL A 1 275 ? 112.524 74.089  116.069 1.00 88.80  ? 275 VAL A CA  1 
ATOM   2143 C  C   . VAL A 1 275 ? 112.007 73.206  117.196 1.00 88.80  ? 275 VAL A C   1 
ATOM   2144 O  O   . VAL A 1 275 ? 111.345 73.686  118.120 1.00 88.80  ? 275 VAL A O   1 
ATOM   2145 C  CB  . VAL A 1 275 ? 111.678 73.959  114.789 1.00 88.80  ? 275 VAL A CB  1 
ATOM   2146 C  CG1 . VAL A 1 275 ? 110.212 73.785  115.104 1.00 88.80  ? 275 VAL A CG1 1 
ATOM   2147 C  CG2 . VAL A 1 275 ? 111.874 75.177  113.916 1.00 88.80  ? 275 VAL A CG2 1 
ATOM   2148 N  N   . GLU A 1 276 ? 112.344 71.919  117.175 1.00 92.50  ? 276 GLU A N   1 
ATOM   2149 C  CA  . GLU A 1 276 ? 111.837 71.015  118.201 1.00 92.50  ? 276 GLU A CA  1 
ATOM   2150 C  C   . GLU A 1 276 ? 112.513 71.244  119.545 1.00 92.50  ? 276 GLU A C   1 
ATOM   2151 O  O   . GLU A 1 276 ? 111.986 70.840  120.586 1.00 92.50  ? 276 GLU A O   1 
ATOM   2152 C  CB  . GLU A 1 276 ? 112.001 69.570  117.751 1.00 92.50  ? 276 GLU A CB  1 
ATOM   2153 C  CG  . GLU A 1 276 ? 111.042 69.194  116.649 1.00 92.50  ? 276 GLU A CG  1 
ATOM   2154 C  CD  . GLU A 1 276 ? 111.238 67.779  116.169 1.00 92.50  ? 276 GLU A CD  1 
ATOM   2155 O  OE1 . GLU A 1 276 ? 112.208 67.139  116.618 1.00 92.50  ? 276 GLU A OE1 1 
ATOM   2156 O  OE2 . GLU A 1 276 ? 110.428 67.308  115.344 1.00 92.50  ? 276 GLU A OE2 1 
ATOM   2157 N  N   . ALA A 1 277 ? 113.673 71.895  119.549 1.00 88.77  ? 277 ALA A N   1 
ATOM   2158 C  CA  . ALA A 1 277 ? 114.289 72.272  120.813 1.00 88.77  ? 277 ALA A CA  1 
ATOM   2159 C  C   . ALA A 1 277 ? 113.615 73.500  121.410 1.00 88.77  ? 277 ALA A C   1 
ATOM   2160 O  O   . ALA A 1 277 ? 113.651 73.705  122.627 1.00 88.77  ? 277 ALA A O   1 
ATOM   2161 C  CB  . ALA A 1 277 ? 115.779 72.523  120.617 1.00 88.77  ? 277 ALA A CB  1 
ATOM   2162 N  N   . SER A 1 278 ? 112.992 74.325  120.574 1.00 86.85  ? 278 SER A N   1 
ATOM   2163 C  CA  . SER A 1 278 ? 112.372 75.563  121.023 1.00 86.85  ? 278 SER A CA  1 
ATOM   2164 C  C   . SER A 1 278 ? 110.868 75.450  121.213 1.00 86.85  ? 278 SER A C   1 
ATOM   2165 O  O   . SER A 1 278 ? 110.247 76.404  121.685 1.00 86.85  ? 278 SER A O   1 
ATOM   2166 C  CB  . SER A 1 278 ? 112.674 76.683  120.035 1.00 86.85  ? 278 SER A CB  1 
ATOM   2167 O  OG  . SER A 1 278 ? 114.045 76.690  119.716 1.00 86.85  ? 278 SER A OG  1 
ATOM   2168 N  N   . LEU A 1 279 ? 110.270 74.323  120.847 1.00 87.26  ? 279 LEU A N   1 
ATOM   2169 C  CA  . LEU A 1 279 ? 108.855 74.110  121.133 1.00 87.26  ? 279 LEU A CA  1 
ATOM   2170 C  C   . LEU A 1 279 ? 108.513 73.989  122.620 1.00 87.26  ? 279 LEU A C   1 
ATOM   2171 O  O   . LEU A 1 279 ? 107.369 74.318  122.972 1.00 87.26  ? 279 LEU A O   1 
ATOM   2172 C  CB  . LEU A 1 279 ? 108.354 72.884  120.361 1.00 87.26  ? 279 LEU A CB  1 
ATOM   2173 C  CG  . LEU A 1 279 ? 108.113 73.104  118.873 1.00 87.26  ? 279 LEU A CG  1 
ATOM   2174 C  CD1 . LEU A 1 279 ? 107.620 71.838  118.228 1.00 87.26  ? 279 LEU A CD1 1 
ATOM   2175 C  CD2 . LEU A 1 279 ? 107.127 74.217  118.665 1.00 87.26  ? 279 LEU A CD2 1 
ATOM   2176 N  N   . PRO A 1 280 ? 109.383 73.501  123.523 1.00 87.20  ? 280 PRO A N   1 
ATOM   2177 C  CA  . PRO A 1 280 ? 109.096 73.714  124.951 1.00 87.20  ? 280 PRO A CA  1 
ATOM   2178 C  C   . PRO A 1 280 ? 109.022 75.170  125.378 1.00 87.20  ? 280 PRO A C   1 
ATOM   2179 O  O   . PRO A 1 280 ? 108.176 75.510  126.213 1.00 87.20  ? 280 PRO A O   1 
ATOM   2180 C  CB  . PRO A 1 280 ? 110.254 72.989  125.635 1.00 87.20  ? 280 PRO A CB  1 
ATOM   2181 C  CG  . PRO A 1 280 ? 110.505 71.870  124.772 1.00 87.20  ? 280 PRO A CG  1 
ATOM   2182 C  CD  . PRO A 1 280 ? 110.296 72.349  123.372 1.00 87.20  ? 280 PRO A CD  1 
ATOM   2183 N  N   . LEU A 1 281 ? 109.883 76.041  124.851 1.00 85.17  ? 281 LEU A N   1 
ATOM   2184 C  CA  . LEU A 1 281 ? 109.835 77.442  125.251 1.00 85.17  ? 281 LEU A CA  1 
ATOM   2185 C  C   . LEU A 1 281 ? 108.637 78.155  124.651 1.00 85.17  ? 281 LEU A C   1 
ATOM   2186 O  O   . LEU A 1 281 ? 108.089 79.069  125.272 1.00 85.17  ? 281 LEU A O   1 
ATOM   2187 C  CB  . LEU A 1 281 ? 111.124 78.155  124.850 1.00 85.17  ? 281 LEU A CB  1 
ATOM   2188 C  CG  . LEU A 1 281 ? 111.277 79.608  125.299 1.00 85.17  ? 281 LEU A CG  1 
ATOM   2189 C  CD1 . LEU A 1 281 ? 111.281 79.686  126.802 1.00 85.17  ? 281 LEU A CD1 1 
ATOM   2190 C  CD2 . LEU A 1 281 ? 112.522 80.232  124.738 1.00 85.17  ? 281 LEU A CD2 1 
ATOM   2191 N  N   . ALA A 1 282 ? 108.206 77.741  123.462 1.00 86.92  ? 282 ALA A N   1 
ATOM   2192 C  CA  . ALA A 1 282 ? 107.078 78.394  122.811 1.00 86.92  ? 282 ALA A CA  1 
ATOM   2193 C  C   . ALA A 1 282 ? 105.775 78.108  123.537 1.00 86.92  ? 282 ALA A C   1 
ATOM   2194 O  O   . ALA A 1 282 ? 104.917 78.986  123.644 1.00 86.92  ? 282 ALA A O   1 
ATOM   2195 C  CB  . ALA A 1 282 ? 106.987 77.947  121.357 1.00 86.92  ? 282 ALA A CB  1 
ATOM   2196 N  N   . GLU A 1 283 ? 105.617 76.893  124.058 1.00 91.45  ? 283 GLU A N   1 
ATOM   2197 C  CA  . GLU A 1 283 ? 104.386 76.543  124.754 1.00 91.45  ? 283 GLU A CA  1 
ATOM   2198 C  C   . GLU A 1 283 ? 104.328 77.201  126.122 1.00 91.45  ? 283 GLU A C   1 
ATOM   2199 O  O   . GLU A 1 283 ? 103.242 77.437  126.657 1.00 91.45  ? 283 GLU A O   1 
ATOM   2200 C  CB  . GLU A 1 283 ? 104.276 75.027  124.876 1.00 91.45  ? 283 GLU A CB  1 
ATOM   2201 C  CG  . GLU A 1 283 ? 104.152 74.326  123.533 1.00 91.45  ? 283 GLU A CG  1 
ATOM   2202 C  CD  . GLU A 1 283 ? 104.206 72.813  123.634 1.00 91.45  ? 283 GLU A CD  1 
ATOM   2203 O  OE1 . GLU A 1 283 ? 104.442 72.294  124.745 1.00 91.45  ? 283 GLU A OE1 1 
ATOM   2204 O  OE2 . GLU A 1 283 ? 104.033 72.143  122.594 1.00 91.45  ? 283 GLU A OE2 1 
ATOM   2205 N  N   . GLU A 1 284 ? 105.486 77.512  126.699 1.00 90.93  ? 284 GLU A N   1 
ATOM   2206 C  CA  . GLU A 1 284 ? 105.505 78.182  127.993 1.00 90.93  ? 284 GLU A CA  1 
ATOM   2207 C  C   . GLU A 1 284 ? 105.184 79.665  127.850 1.00 90.93  ? 284 GLU A C   1 
ATOM   2208 O  O   . GLU A 1 284 ? 104.403 80.218  128.631 1.00 90.93  ? 284 GLU A O   1 
ATOM   2209 C  CB  . GLU A 1 284 ? 106.862 77.979  128.657 1.00 90.93  ? 284 GLU A CB  1 
ATOM   2210 C  CG  . GLU A 1 284 ? 107.103 78.859  129.853 1.00 90.93  ? 284 GLU A CG  1 
ATOM   2211 C  CD  . GLU A 1 284 ? 108.568 79.049  130.135 1.00 90.93  ? 284 GLU A CD  1 
ATOM   2212 O  OE1 . GLU A 1 284 ? 109.332 78.075  129.981 1.00 90.93  ? 284 GLU A OE1 1 
ATOM   2213 O  OE2 . GLU A 1 284 ? 108.959 80.174  130.504 1.00 90.93  ? 284 GLU A OE2 1 
ATOM   2214 N  N   . LEU A 1 285 ? 105.758 80.320  126.846 1.00 85.38  ? 285 LEU A N   1 
ATOM   2215 C  CA  . LEU A 1 285 ? 105.488 81.729  126.604 1.00 85.38  ? 285 LEU A CA  1 
ATOM   2216 C  C   . LEU A 1 285 ? 104.219 81.970  125.800 1.00 85.38  ? 285 LEU A C   1 
ATOM   2217 O  O   . LEU A 1 285 ? 103.811 83.129  125.680 1.00 85.38  ? 285 LEU A O   1 
ATOM   2218 C  CB  . LEU A 1 285 ? 106.660 82.368  125.870 1.00 85.38  ? 285 LEU A CB  1 
ATOM   2219 C  CG  . LEU A 1 285 ? 108.035 82.206  126.489 1.00 85.38  ? 285 LEU A CG  1 
ATOM   2220 C  CD1 . LEU A 1 285 ? 109.038 82.977  125.679 1.00 85.38  ? 285 LEU A CD1 1 
ATOM   2221 C  CD2 . LEU A 1 285 ? 108.029 82.692  127.912 1.00 85.38  ? 285 LEU A CD2 1 
ATOM   2222 N  N   . ASP A 1 286 ? 103.609 80.911  125.252 1.00 87.40  ? 286 ASP A N   1 
ATOM   2223 C  CA  . ASP A 1 286 ? 102.405 80.972  124.410 1.00 87.40  ? 286 ASP A CA  1 
ATOM   2224 C  C   . ASP A 1 286 ? 102.627 81.860  123.186 1.00 87.40  ? 286 ASP A C   1 
ATOM   2225 O  O   . ASP A 1 286 ? 101.918 82.837  122.956 1.00 87.40  ? 286 ASP A O   1 
ATOM   2226 C  CB  . ASP A 1 286 ? 101.177 81.428  125.205 1.00 87.40  ? 286 ASP A CB  1 
ATOM   2227 C  CG  . ASP A 1 286 ? 99.878  80.947  124.599 1.00 87.40  ? 286 ASP A CG  1 
ATOM   2228 O  OD1 . ASP A 1 286 ? 99.279  80.018  125.170 1.00 87.40  ? 286 ASP A OD1 1 
ATOM   2229 O  OD2 . ASP A 1 286 ? 99.467  81.463  123.543 1.00 87.40  ? 286 ASP A OD2 1 
ATOM   2230 N  N   . VAL A 1 287 ? 103.654 81.530  122.415 1.00 82.27  ? 287 VAL A N   1 
ATOM   2231 C  CA  . VAL A 1 287 ? 103.922 82.148  121.126 1.00 82.27  ? 287 VAL A CA  1 
ATOM   2232 C  C   . VAL A 1 287 ? 103.956 81.032  120.096 1.00 82.27  ? 287 VAL A C   1 
ATOM   2233 O  O   . VAL A 1 287 ? 104.542 79.975  120.340 1.00 82.27  ? 287 VAL A O   1 
ATOM   2234 C  CB  . VAL A 1 287 ? 105.245 82.943  121.126 1.00 82.27  ? 287 VAL A CB  1 
ATOM   2235 C  CG1 . VAL A 1 287 ? 105.402 83.696  119.848 1.00 82.27  ? 287 VAL A CG1 1 
ATOM   2236 C  CG2 . VAL A 1 287 ? 105.285 83.918  122.267 1.00 82.27  ? 287 VAL A CG2 1 
ATOM   2237 N  N   . ILE A 1 288 ? 103.310 81.246  118.964 1.00 78.91  ? 288 ILE A N   1 
ATOM   2238 C  CA  . ILE A 1 288 ? 103.239 80.243  117.913 1.00 78.91  ? 288 ILE A CA  1 
ATOM   2239 C  C   . ILE A 1 288 ? 104.391 80.470  116.948 1.00 78.91  ? 288 ILE A C   1 
ATOM   2240 O  O   . ILE A 1 288 ? 104.649 81.604  116.533 1.00 78.91  ? 288 ILE A O   1 
ATOM   2241 C  CB  . ILE A 1 288 ? 101.878 80.296  117.200 1.00 78.91  ? 288 ILE A CB  1 
ATOM   2242 C  CG1 . ILE A 1 288 ? 100.770 80.043  118.210 1.00 78.91  ? 288 ILE A CG1 1 
ATOM   2243 C  CG2 . ILE A 1 288 ? 101.796 79.270  116.100 1.00 78.91  ? 288 ILE A CG2 1 
ATOM   2244 C  CD1 . ILE A 1 288 ? 99.408  80.332  117.692 1.00 78.91  ? 288 ILE A CD1 1 
ATOM   2245 N  N   . ILE A 1 289 ? 105.105 79.400  116.617 1.00 79.48  ? 289 ILE A N   1 
ATOM   2246 C  CA  . ILE A 1 289 ? 106.160 79.444  115.611 1.00 79.48  ? 289 ILE A CA  1 
ATOM   2247 C  C   . ILE A 1 289 ? 105.530 79.142  114.259 1.00 79.48  ? 289 ILE A C   1 
ATOM   2248 O  O   . ILE A 1 289 ? 104.893 78.101  114.089 1.00 79.48  ? 289 ILE A O   1 
ATOM   2249 C  CB  . ILE A 1 289 ? 107.273 78.436  115.929 1.00 79.48  ? 289 ILE A CB  1 
ATOM   2250 C  CG1 . ILE A 1 289 ? 107.863 78.698  117.306 1.00 79.48  ? 289 ILE A CG1 1 
ATOM   2251 C  CG2 . ILE A 1 289 ? 108.357 78.501  114.889 1.00 79.48  ? 289 ILE A CG2 1 
ATOM   2252 C  CD1 . ILE A 1 289 ? 108.839 77.655  117.733 1.00 79.48  ? 289 ILE A CD1 1 
ATOM   2253 N  N   . CYS A 1 290 ? 105.699 80.039  113.297 1.00 80.89  ? 290 CYS A N   1 
ATOM   2254 C  CA  . CYS A 1 290 ? 105.103 79.865  111.975 1.00 80.89  ? 290 CYS A CA  1 
ATOM   2255 C  C   . CYS A 1 290 ? 106.081 80.221  110.862 1.00 80.89  ? 290 CYS A C   1 
ATOM   2256 O  O   . CYS A 1 290 ? 106.294 81.415  110.579 1.00 80.89  ? 290 CYS A O   1 
ATOM   2257 C  CB  . CYS A 1 290 ? 103.806 80.666  111.873 1.00 80.89  ? 290 CYS A CB  1 
ATOM   2258 S  SG  . CYS A 1 290 ? 103.861 82.421  112.291 1.00 80.89  ? 290 CYS A SG  1 
ATOM   2259 N  N   . PRO A 1 291 ? 106.690 79.240  110.207 1.00 81.88  ? 291 PRO A N   1 
ATOM   2260 C  CA  . PRO A 1 291 ? 107.549 79.543  109.061 1.00 81.88  ? 291 PRO A CA  1 
ATOM   2261 C  C   . PRO A 1 291 ? 106.738 79.961  107.845 1.00 81.88  ? 291 PRO A C   1 
ATOM   2262 O  O   . PRO A 1 291 ? 105.569 79.604  107.698 1.00 81.88  ? 291 PRO A O   1 
ATOM   2263 C  CB  . PRO A 1 291 ? 108.283 78.225  108.818 1.00 81.88  ? 291 PRO A CB  1 
ATOM   2264 C  CG  . PRO A 1 291 ? 107.413 77.208  109.417 1.00 81.88  ? 291 PRO A CG  1 
ATOM   2265 C  CD  . PRO A 1 291 ? 106.781 77.831  110.599 1.00 81.88  ? 291 PRO A CD  1 
ATOM   2266 N  N   . GLU A 1 292 ? 107.381 80.715  106.963 1.00 85.90  ? 292 GLU A N   1 
ATOM   2267 C  CA  . GLU A 1 292 ? 106.694 81.357  105.854 1.00 85.90  ? 292 GLU A CA  1 
ATOM   2268 C  C   . GLU A 1 292 ? 106.649 80.449  104.631 1.00 85.90  ? 292 GLU A C   1 
ATOM   2269 O  O   . GLU A 1 292 ? 107.635 79.793  104.290 1.00 85.90  ? 292 GLU A O   1 
ATOM   2270 C  CB  . GLU A 1 292 ? 107.394 82.669  105.511 1.00 85.90  ? 292 GLU A CB  1 
ATOM   2271 C  CG  . GLU A 1 292 ? 106.674 83.559  104.533 1.00 85.90  ? 292 GLU A CG  1 
ATOM   2272 C  CD  . GLU A 1 292 ? 107.477 84.795  104.203 1.00 85.90  ? 292 GLU A CD  1 
ATOM   2273 O  OE1 . GLU A 1 292 ? 108.675 84.822  104.531 1.00 85.90  ? 292 GLU A OE1 1 
ATOM   2274 O  OE2 . GLU A 1 292 ? 106.920 85.741  103.615 1.00 85.90  ? 292 GLU A OE2 1 
ATOM   2275 N  N   . ILE A 1 293 ? 105.494 80.412  103.976 1.00 87.19  ? 293 ILE A N   1 
ATOM   2276 C  CA  . ILE A 1 293 ? 105.307 79.708  102.714 1.00 87.19  ? 293 ILE A CA  1 
ATOM   2277 C  C   . ILE A 1 293 ? 105.204 80.770  101.630 1.00 87.19  ? 293 ILE A C   1 
ATOM   2278 O  O   . ILE A 1 293 ? 104.147 81.373  101.439 1.00 87.19  ? 293 ILE A O   1 
ATOM   2279 C  CB  . ILE A 1 293 ? 104.061 78.817  102.735 1.00 87.19  ? 293 ILE A CB  1 
ATOM   2280 C  CG1 . ILE A 1 293 ? 104.117 77.834  103.898 1.00 87.19  ? 293 ILE A CG1 1 
ATOM   2281 C  CG2 . ILE A 1 293 ? 103.922 78.071  101.431 1.00 87.19  ? 293 ILE A CG2 1 
ATOM   2282 C  CD1 . ILE A 1 293 ? 105.376 77.021  103.952 1.00 87.19  ? 293 ILE A CD1 1 
ATOM   2283 N  N   . HIS A 1 294 ? 106.296 81.003  100.914 1.00 90.61  ? 294 HIS A N   1 
ATOM   2284 C  CA  . HIS A 1 294 ? 106.374 82.095  99.960  1.00 90.61  ? 294 HIS A CA  1 
ATOM   2285 C  C   . HIS A 1 294 ? 106.958 81.593  98.651  1.00 90.61  ? 294 HIS A C   1 
ATOM   2286 O  O   . HIS A 1 294 ? 107.629 80.564  98.604  1.00 90.61  ? 294 HIS A O   1 
ATOM   2287 C  CB  . HIS A 1 294 ? 107.217 83.255  100.500 1.00 90.61  ? 294 HIS A CB  1 
ATOM   2288 C  CG  . HIS A 1 294 ? 108.648 82.897  100.750 1.00 90.61  ? 294 HIS A CG  1 
ATOM   2289 N  ND1 . HIS A 1 294 ? 109.691 83.499  100.083 1.00 90.61  ? 294 HIS A ND1 1 
ATOM   2290 C  CD2 . HIS A 1 294 ? 109.210 82.002  101.595 1.00 90.61  ? 294 HIS A CD2 1 
ATOM   2291 C  CE1 . HIS A 1 294 ? 110.833 82.986  100.502 1.00 90.61  ? 294 HIS A CE1 1 
ATOM   2292 N  NE2 . HIS A 1 294 ? 110.569 82.076  101.420 1.00 90.61  ? 294 HIS A NE2 1 
ATOM   2293 N  N   . SER A 1 295 ? 106.688 82.348  97.593  1.00 94.11  ? 295 SER A N   1 
ATOM   2294 C  CA  . SER A 1 295 ? 107.130 81.996  96.252  1.00 94.11  ? 295 SER A CA  1 
ATOM   2295 C  C   . SER A 1 295 ? 108.653 82.033  96.173  1.00 94.11  ? 295 SER A C   1 
ATOM   2296 O  O   . SER A 1 295 ? 109.274 82.912  96.781  1.00 94.11  ? 295 SER A O   1 
ATOM   2297 C  CB  . SER A 1 295 ? 106.517 82.977  95.258  1.00 94.11  ? 295 SER A CB  1 
ATOM   2298 O  OG  . SER A 1 295 ? 106.914 82.717  93.931  1.00 94.11  ? 295 SER A OG  1 
ATOM   2299 N  N   . PRO A 1 296 ? 109.296 81.116  95.435  1.00 95.19  ? 296 PRO A N   1 
ATOM   2300 C  CA  . PRO A 1 296 ? 108.807 80.108  94.494  1.00 95.19  ? 296 PRO A CA  1 
ATOM   2301 C  C   . PRO A 1 296 ? 108.346 78.788  95.079  1.00 95.19  ? 296 PRO A C   1 
ATOM   2302 O  O   . PRO A 1 296 ? 108.243 77.838  94.317  1.00 95.19  ? 296 PRO A O   1 
ATOM   2303 C  CB  . PRO A 1 296 ? 110.027 79.863  93.620  1.00 95.19  ? 296 PRO A CB  1 
ATOM   2304 C  CG  . PRO A 1 296 ? 111.142 80.011  94.547  1.00 95.19  ? 296 PRO A CG  1 
ATOM   2305 C  CD  . PRO A 1 296 ? 110.765 81.126  95.475  1.00 95.19  ? 296 PRO A CD  1 
ATOM   2306 N  N   . THR A 1 297 ? 108.088 78.707  96.373  1.00 95.23  ? 297 THR A N   1 
ATOM   2307 C  CA  . THR A 1 297 ? 107.583 77.466  96.946  1.00 95.23  ? 297 THR A CA  1 
ATOM   2308 C  C   . THR A 1 297 ? 106.063 77.437  96.857  1.00 95.23  ? 297 THR A C   1 
ATOM   2309 O  O   . THR A 1 297 ? 105.405 78.287  97.463  1.00 95.23  ? 297 THR A O   1 
ATOM   2310 C  CB  . THR A 1 297 ? 108.014 77.323  98.396  1.00 95.23  ? 297 THR A CB  1 
ATOM   2311 O  OG1 . THR A 1 297 ? 109.440 77.381  98.478  1.00 95.23  ? 297 THR A OG1 1 
ATOM   2312 C  CG2 . THR A 1 297 ? 107.532 76.012  98.963  1.00 95.23  ? 297 THR A CG2 1 
ATOM   2313 N  N   . PRO A 1 298 ? 105.471 76.502  96.127  1.00 97.20  ? 298 PRO A N   1 
ATOM   2314 C  CA  . PRO A 1 298 ? 104.015 76.371  96.136  1.00 97.20  ? 298 PRO A CA  1 
ATOM   2315 C  C   . PRO A 1 298 ? 103.545 75.637  97.382  1.00 97.20  ? 298 PRO A C   1 
ATOM   2316 O  O   . PRO A 1 298 ? 104.333 75.215  98.225  1.00 97.20  ? 298 PRO A O   1 
ATOM   2317 C  CB  . PRO A 1 298 ? 103.733 75.557  94.875  1.00 97.20  ? 298 PRO A CB  1 
ATOM   2318 C  CG  . PRO A 1 298 ? 104.934 74.723  94.721  1.00 97.20  ? 298 PRO A CG  1 
ATOM   2319 C  CD  . PRO A 1 298 ? 106.096 75.530  95.218  1.00 97.20  ? 298 PRO A CD  1 
ATOM   2320 N  N   . ILE A 1 299 ? 102.226 75.489  97.485  1.00 97.24  ? 299 ILE A N   1 
ATOM   2321 C  CA  . ILE A 1 299 ? 101.657 74.782  98.627  1.00 97.24  ? 299 ILE A CA  1 
ATOM   2322 C  C   . ILE A 1 299 ? 101.899 73.284  98.491  1.00 97.24  ? 299 ILE A C   1 
ATOM   2323 O  O   . ILE A 1 299 ? 102.253 72.603  99.462  1.00 97.24  ? 299 ILE A O   1 
ATOM   2324 C  CB  . ILE A 1 299 ? 100.163 75.129  98.767  1.00 97.24  ? 299 ILE A CB  1 
ATOM   2325 C  CG1 . ILE A 1 299 ? 100.014 76.550  99.296  1.00 97.24  ? 299 ILE A CG1 1 
ATOM   2326 C  CG2 . ILE A 1 299 ? 99.453  74.185  99.711  1.00 97.24  ? 299 ILE A CG2 1 
ATOM   2327 C  CD1 . ILE A 1 299 ? 98.599  77.041  99.328  1.00 97.24  ? 299 ILE A CD1 1 
ATOM   2328 N  N   . LYS A 1 300 ? 101.768 72.756  97.274  1.00 99.71  ? 300 LYS A N   1 
ATOM   2329 C  CA  . LYS A 1 300 ? 102.024 71.342  97.002  1.00 99.71  ? 300 LYS A CA  1 
ATOM   2330 C  C   . LYS A 1 300 ? 103.527 71.135  96.848  1.00 99.71  ? 300 LYS A C   1 
ATOM   2331 O  O   . LYS A 1 300 ? 104.055 70.956  95.751  1.00 99.71  ? 300 LYS A O   1 
ATOM   2332 C  CB  . LYS A 1 300 ? 101.280 70.899  95.751  1.00 99.71  ? 300 LYS A CB  1 
ATOM   2333 C  CG  . LYS A 1 300 ? 99.810  71.239  95.726  1.00 99.71  ? 300 LYS A CG  1 
ATOM   2334 C  CD  . LYS A 1 300 ? 99.000  70.242  96.509  1.00 99.71  ? 300 LYS A CD  1 
ATOM   2335 C  CE  . LYS A 1 300 ? 97.525  70.425  96.220  1.00 99.71  ? 300 LYS A CE  1 
ATOM   2336 N  NZ  . LYS A 1 300 ? 97.213  70.127  94.797  1.00 99.71  ? 300 LYS A NZ  1 
ATOM   2337 N  N   . HIS A 1 301 ? 104.230 71.150  97.976  1.00 100.56 ? 301 HIS A N   1 
ATOM   2338 C  CA  . HIS A 1 301 ? 105.681 71.066  97.961  1.00 100.56 ? 301 HIS A CA  1 
ATOM   2339 C  C   . HIS A 1 301 ? 106.154 70.172  99.095  1.00 100.56 ? 301 HIS A C   1 
ATOM   2340 O  O   . HIS A 1 301 ? 105.441 69.941  100.071 1.00 100.56 ? 301 HIS A O   1 
ATOM   2341 C  CB  . HIS A 1 301 ? 106.320 72.453  98.071  1.00 100.56 ? 301 HIS A CB  1 
ATOM   2342 C  CG  . HIS A 1 301 ? 107.729 72.509  97.579  1.00 100.56 ? 301 HIS A CG  1 
ATOM   2343 N  ND1 . HIS A 1 301 ? 108.813 72.350  98.413  1.00 100.56 ? 301 HIS A ND1 1 
ATOM   2344 C  CD2 . HIS A 1 301 ? 108.234 72.698  96.338  1.00 100.56 ? 301 HIS A CD2 1 
ATOM   2345 C  CE1 . HIS A 1 301 ? 109.926 72.445  97.708  1.00 100.56 ? 301 HIS A CE1 1 
ATOM   2346 N  NE2 . HIS A 1 301 ? 109.601 72.656  96.446  1.00 100.56 ? 301 HIS A NE2 1 
ATOM   2347 N  N   . GLU A 1 302 ? 107.378 69.667  98.947  1.00 102.45 ? 302 GLU A N   1 
ATOM   2348 C  CA  . GLU A 1 302 ? 107.941 68.758  99.937  1.00 102.45 ? 302 GLU A CA  1 
ATOM   2349 C  C   . GLU A 1 302 ? 108.336 69.500  101.204 1.00 102.45 ? 302 GLU A C   1 
ATOM   2350 O  O   . GLU A 1 302 ? 108.337 68.921  102.296 1.00 102.45 ? 302 GLU A O   1 
ATOM   2351 C  CB  . GLU A 1 302 ? 109.150 68.030  99.352  1.00 102.45 ? 302 GLU A CB  1 
ATOM   2352 C  CG  . GLU A 1 302 ? 108.831 67.074  98.209  1.00 102.45 ? 302 GLU A CG  1 
ATOM   2353 C  CD  . GLU A 1 302 ? 108.777 67.756  96.851  1.00 102.45 ? 302 GLU A CD  1 
ATOM   2354 O  OE1 . GLU A 1 302 ? 109.049 68.971  96.778  1.00 102.45 ? 302 GLU A OE1 1 
ATOM   2355 O  OE2 . GLU A 1 302 ? 108.457 67.074  95.856  1.00 102.45 ? 302 GLU A OE2 1 
ATOM   2356 N  N   . VAL A 1 303 ? 108.695 70.777  101.071 1.00 98.32  ? 303 VAL A N   1 
ATOM   2357 C  CA  . VAL A 1 303 ? 109.047 71.593  102.228 1.00 98.32  ? 303 VAL A CA  1 
ATOM   2358 C  C   . VAL A 1 303 ? 107.819 71.838  103.092 1.00 98.32  ? 303 VAL A C   1 
ATOM   2359 O  O   . VAL A 1 303 ? 107.879 71.756  104.325 1.00 98.32  ? 303 VAL A O   1 
ATOM   2360 C  CB  . VAL A 1 303 ? 109.694 72.908  101.752 1.00 98.32  ? 303 VAL A CB  1 
ATOM   2361 C  CG1 . VAL A 1 303 ? 109.767 73.938  102.860 1.00 98.32  ? 303 VAL A CG1 1 
ATOM   2362 C  CG2 . VAL A 1 303 ? 111.071 72.635  101.197 1.00 98.32  ? 303 VAL A CG2 1 
ATOM   2363 N  N   . VAL A 1 304 ? 106.678 72.090  102.454 1.00 96.86  ? 304 VAL A N   1 
ATOM   2364 C  CA  . VAL A 1 304 ? 105.448 72.382  103.178 1.00 96.86  ? 304 VAL A CA  1 
ATOM   2365 C  C   . VAL A 1 304 ? 104.931 71.135  103.878 1.00 96.86  ? 304 VAL A C   1 
ATOM   2366 O  O   . VAL A 1 304 ? 104.429 71.205  105.002 1.00 96.86  ? 304 VAL A O   1 
ATOM   2367 C  CB  . VAL A 1 304 ? 104.413 72.970  102.204 1.00 96.86  ? 304 VAL A CB  1 
ATOM   2368 C  CG1 . VAL A 1 304 ? 103.107 73.279  102.899 1.00 96.86  ? 304 VAL A CG1 1 
ATOM   2369 C  CG2 . VAL A 1 304 ? 104.978 74.198  101.531 1.00 96.86  ? 304 VAL A CG2 1 
ATOM   2370 N  N   . ASP A 1 305 ? 105.096 69.969  103.252 1.00 100.23 ? 305 ASP A N   1 
ATOM   2371 C  CA  . ASP A 1 305 ? 104.660 68.721  103.870 1.00 100.23 ? 305 ASP A CA  1 
ATOM   2372 C  C   . ASP A 1 305 ? 105.519 68.358  105.072 1.00 100.23 ? 305 ASP A C   1 
ATOM   2373 O  O   . ASP A 1 305 ? 105.079 67.617  105.955 1.00 100.23 ? 305 ASP A O   1 
ATOM   2374 C  CB  . ASP A 1 305 ? 104.685 67.587  102.848 1.00 100.23 ? 305 ASP A CB  1 
ATOM   2375 C  CG  . ASP A 1 305 ? 103.773 67.841  101.674 1.00 100.23 ? 305 ASP A CG  1 
ATOM   2376 O  OD1 . ASP A 1 305 ? 103.066 68.869  101.678 1.00 100.23 ? 305 ASP A OD1 1 
ATOM   2377 O  OD2 . ASP A 1 305 ? 103.762 67.015  100.741 1.00 100.23 ? 305 ASP A OD2 1 
ATOM   2378 N  N   . ASP A 1 306 ? 106.748 68.871  105.125 1.00 99.23  ? 306 ASP A N   1 
ATOM   2379 C  CA  . ASP A 1 306 ? 107.597 68.636  106.286 1.00 99.23  ? 306 ASP A CA  1 
ATOM   2380 C  C   . ASP A 1 306 ? 107.125 69.441  107.486 1.00 99.23  ? 306 ASP A C   1 
ATOM   2381 O  O   . ASP A 1 306 ? 107.298 69.020  108.633 1.00 99.23  ? 306 ASP A O   1 
ATOM   2382 C  CB  . ASP A 1 306 ? 109.045 68.970  105.947 1.00 99.23  ? 306 ASP A CB  1 
ATOM   2383 C  CG  . ASP A 1 306 ? 109.730 67.856  105.200 1.00 99.23  ? 306 ASP A CG  1 
ATOM   2384 O  OD1 . ASP A 1 306 ? 109.573 66.690  105.610 1.00 99.23  ? 306 ASP A OD1 1 
ATOM   2385 O  OD2 . ASP A 1 306 ? 110.427 68.139  104.205 1.00 99.23  ? 306 ASP A OD2 1 
ATOM   2386 N  N   . TYR A 1 307 ? 106.527 70.607  107.239 1.00 94.41  ? 307 TYR A N   1 
ATOM   2387 C  CA  . TYR A 1 307 ? 105.955 71.395  108.325 1.00 94.41  ? 307 TYR A CA  1 
ATOM   2388 C  C   . TYR A 1 307 ? 104.719 70.717  108.899 1.00 94.41  ? 307 TYR A C   1 
ATOM   2389 O  O   . TYR A 1 307 ? 104.509 70.718  110.113 1.00 94.41  ? 307 TYR A O   1 
ATOM   2390 C  CB  . TYR A 1 307 ? 105.606 72.794  107.833 1.00 94.41  ? 307 TYR A CB  1 
ATOM   2391 C  CG  . TYR A 1 307 ? 106.789 73.640  107.455 1.00 94.41  ? 307 TYR A CG  1 
ATOM   2392 C  CD1 . TYR A 1 307 ? 108.000 73.492  108.092 1.00 94.41  ? 307 TYR A CD1 1 
ATOM   2393 C  CD2 . TYR A 1 307 ? 106.687 74.598  106.463 1.00 94.41  ? 307 TYR A CD2 1 
ATOM   2394 C  CE1 . TYR A 1 307 ? 109.082 74.269  107.751 1.00 94.41  ? 307 TYR A CE1 1 
ATOM   2395 C  CE2 . TYR A 1 307 ? 107.764 75.378  106.115 1.00 94.41  ? 307 TYR A CE2 1 
ATOM   2396 C  CZ  . TYR A 1 307 ? 108.956 75.209  106.762 1.00 94.41  ? 307 TYR A CZ  1 
ATOM   2397 O  OH  . TYR A 1 307 ? 110.029 75.988  106.414 1.00 94.41  ? 307 TYR A OH  1 
ATOM   2398 N  N   . ILE A 1 308 ? 103.885 70.136  108.036 1.00 95.67  ? 308 ILE A N   1 
ATOM   2399 C  CA  . ILE A 1 308 ? 102.683 69.456  108.507 1.00 95.67  ? 308 ILE A CA  1 
ATOM   2400 C  C   . ILE A 1 308 ? 103.050 68.164  109.221 1.00 95.67  ? 308 ILE A C   1 
ATOM   2401 O  O   . ILE A 1 308 ? 102.384 67.755  110.180 1.00 95.67  ? 308 ILE A O   1 
ATOM   2402 C  CB  . ILE A 1 308 ? 101.720 69.199  107.335 1.00 95.67  ? 308 ILE A CB  1 
ATOM   2403 C  CG1 . ILE A 1 308 ? 101.612 70.437  106.454 1.00 95.67  ? 308 ILE A CG1 1 
ATOM   2404 C  CG2 . ILE A 1 308 ? 100.350 68.800  107.842 1.00 95.67  ? 308 ILE A CG2 1 
ATOM   2405 C  CD1 . ILE A 1 308 ? 100.912 71.579  107.106 1.00 95.67  ? 308 ILE A CD1 1 
ATOM   2406 N  N   . ALA A 1 309 ? 104.120 67.507  108.772 1.00 96.33  ? 309 ALA A N   1 
ATOM   2407 C  CA  . ALA A 1 309 ? 104.558 66.278  109.419 1.00 96.33  ? 309 ALA A CA  1 
ATOM   2408 C  C   . ALA A 1 309 ? 105.139 66.556  110.795 1.00 96.33  ? 309 ALA A C   1 
ATOM   2409 O  O   . ALA A 1 309 ? 105.075 65.703  111.684 1.00 96.33  ? 309 ALA A O   1 
ATOM   2410 C  CB  . ALA A 1 309 ? 105.583 65.563  108.545 1.00 96.33  ? 309 ALA A CB  1 
ATOM   2411 N  N   . LEU A 1 310 ? 105.707 67.747  110.988 1.00 95.11  ? 310 LEU A N   1 
ATOM   2412 C  CA  . LEU A 1 310 ? 106.271 68.098  112.286 1.00 95.11  ? 310 LEU A CA  1 
ATOM   2413 C  C   . LEU A 1 310 ? 105.175 68.339  113.314 1.00 95.11  ? 310 LEU A C   1 
ATOM   2414 O  O   . LEU A 1 310 ? 105.362 68.069  114.504 1.00 95.11  ? 310 LEU A O   1 
ATOM   2415 C  CB  . LEU A 1 310 ? 107.170 69.327  112.143 1.00 95.11  ? 310 LEU A CB  1 
ATOM   2416 C  CG  . LEU A 1 310 ? 108.048 69.810  113.300 1.00 95.11  ? 310 LEU A CG  1 
ATOM   2417 C  CD1 . LEU A 1 310 ? 109.333 70.348  112.740 1.00 95.11  ? 310 LEU A CD1 1 
ATOM   2418 C  CD2 . LEU A 1 310 ? 107.378 70.906  114.099 1.00 95.11  ? 310 LEU A CD2 1 
ATOM   2419 N  N   . ILE A 1 311 ? 104.026 68.846  112.872 1.00 95.07  ? 311 ILE A N   1 
ATOM   2420 C  CA  . ILE A 1 311 ? 102.936 69.135  113.796 1.00 95.07  ? 311 ILE A CA  1 
ATOM   2421 C  C   . ILE A 1 311 ? 102.294 67.844  114.276 1.00 95.07  ? 311 ILE A C   1 
ATOM   2422 O  O   . ILE A 1 311 ? 101.976 67.694  115.459 1.00 95.07  ? 311 ILE A O   1 
ATOM   2423 C  CB  . ILE A 1 311 ? 101.911 70.071  113.133 1.00 95.07  ? 311 ILE A CB  1 
ATOM   2424 C  CG1 . ILE A 1 311 ? 102.587 71.367  112.715 1.00 95.07  ? 311 ILE A CG1 1 
ATOM   2425 C  CG2 . ILE A 1 311 ? 100.777 70.390  114.076 1.00 95.07  ? 311 ILE A CG2 1 
ATOM   2426 C  CD1 . ILE A 1 311 ? 101.701 72.320  111.969 1.00 95.07  ? 311 ILE A CD1 1 
ATOM   2427 N  N   . ARG A 1 312 ? 102.120 66.879  113.374 1.00 99.37  ? 312 ARG A N   1 
ATOM   2428 C  CA  . ARG A 1 312 ? 101.480 65.628  113.763 1.00 99.37  ? 312 ARG A CA  1 
ATOM   2429 C  C   . ARG A 1 312 ? 102.418 64.752  114.579 1.00 99.37  ? 312 ARG A C   1 
ATOM   2430 O  O   . ARG A 1 312 ? 101.968 63.974  115.426 1.00 99.37  ? 312 ARG A O   1 
ATOM   2431 C  CB  . ARG A 1 312 ? 100.993 64.886  112.524 1.00 99.37  ? 312 ARG A CB  1 
ATOM   2432 C  CG  . ARG A 1 312 ? 99.750  65.486  111.919 1.00 99.37  ? 312 ARG A CG  1 
ATOM   2433 C  CD  . ARG A 1 312 ? 99.545  65.007  110.504 1.00 99.37  ? 312 ARG A CD  1 
ATOM   2434 N  NE  . ARG A 1 312 ? 98.564  65.825  109.804 1.00 99.37  ? 312 ARG A NE  1 
ATOM   2435 C  CZ  . ARG A 1 312 ? 98.439  65.866  108.483 1.00 99.37  ? 312 ARG A CZ  1 
ATOM   2436 N  NH1 . ARG A 1 312 ? 99.236  65.135  107.717 1.00 99.37  ? 312 ARG A NH1 1 
ATOM   2437 N  NH2 . ARG A 1 312 ? 97.520  66.644  107.928 1.00 99.37  ? 312 ARG A NH2 1 
ATOM   2438 N  N   . ARG A 1 313 ? 103.724 64.865  114.342 1.00 98.81  ? 313 ARG A N   1 
ATOM   2439 C  CA  . ARG A 1 313 ? 104.682 64.070  115.101 1.00 98.81  ? 313 ARG A CA  1 
ATOM   2440 C  C   . ARG A 1 313 ? 104.821 64.595  116.522 1.00 98.81  ? 313 ARG A C   1 
ATOM   2441 O  O   . ARG A 1 313 ? 104.814 63.819  117.484 1.00 98.81  ? 313 ARG A O   1 
ATOM   2442 C  CB  . ARG A 1 313 ? 106.031 64.066  114.384 1.00 98.81  ? 313 ARG A CB  1 
ATOM   2443 C  CG  . ARG A 1 313 ? 107.198 63.633  115.237 1.00 98.81  ? 313 ARG A CG  1 
ATOM   2444 C  CD  . ARG A 1 313 ? 108.483 63.620  114.438 1.00 98.81  ? 313 ARG A CD  1 
ATOM   2445 N  NE  . ARG A 1 313 ? 108.989 64.963  114.176 1.00 98.81  ? 313 ARG A NE  1 
ATOM   2446 C  CZ  . ARG A 1 313 ? 109.106 65.492  112.963 1.00 98.81  ? 313 ARG A CZ  1 
ATOM   2447 N  NH1 . ARG A 1 313 ? 108.750 64.793  111.897 1.00 98.81  ? 313 ARG A NH1 1 
ATOM   2448 N  NH2 . ARG A 1 313 ? 109.580 66.719  112.815 1.00 98.81  ? 313 ARG A NH2 1 
ATOM   2449 N  N   . THR A 1 314 ? 104.930 65.913  116.675 1.00 99.14  ? 314 THR A N   1 
ATOM   2450 C  CA  . THR A 1 314 ? 105.086 66.501  117.998 1.00 99.14  ? 314 THR A CA  1 
ATOM   2451 C  C   . THR A 1 314 ? 103.758 66.692  118.716 1.00 99.14  ? 314 THR A C   1 
ATOM   2452 O  O   . THR A 1 314 ? 103.720 66.637  119.949 1.00 99.14  ? 314 THR A O   1 
ATOM   2453 C  CB  . THR A 1 314 ? 105.813 67.839  117.893 1.00 99.14  ? 314 THR A CB  1 
ATOM   2454 O  OG1 . THR A 1 314 ? 105.237 68.613  116.839 1.00 99.14  ? 314 THR A OG1 1 
ATOM   2455 C  CG2 . THR A 1 314 ? 107.275 67.618  117.589 1.00 99.14  ? 314 THR A CG2 1 
ATOM   2456 N  N   . GLY A 1 315 ? 102.674 66.903  117.979 1.00 99.19  ? 315 GLY A N   1 
ATOM   2457 C  CA  . GLY A 1 315 ? 101.381 67.117  118.608 1.00 99.19  ? 315 GLY A CA  1 
ATOM   2458 C  C   . GLY A 1 315 ? 101.248 68.470  119.269 1.00 99.19  ? 315 GLY A C   1 
ATOM   2459 O  O   . GLY A 1 315 ? 100.539 68.601  120.274 1.00 99.19  ? 315 GLY A O   1 
ATOM   2460 N  N   . THR A 1 316 ? 101.907 69.482  118.724 1.00 96.00  ? 316 THR A N   1 
ATOM   2461 C  CA  . THR A 1 316 ? 101.954 70.788  119.355 1.00 96.00  ? 316 THR A CA  1 
ATOM   2462 C  C   . THR A 1 316 ? 100.885 71.714  118.796 1.00 96.00  ? 316 THR A C   1 
ATOM   2463 O  O   . THR A 1 316 ? 100.423 71.558  117.664 1.00 96.00  ? 316 THR A O   1 
ATOM   2464 C  CB  . THR A 1 316 ? 103.333 71.423  119.187 1.00 96.00  ? 316 THR A CB  1 
ATOM   2465 O  OG1 . THR A 1 316 ? 103.343 72.709  119.813 1.00 96.00  ? 316 THR A OG1 1 
ATOM   2466 C  CG2 . THR A 1 316 ? 103.694 71.563  117.727 1.00 96.00  ? 316 THR A CG2 1 
ATOM   2467 N  N   . LYS A 1 317 ? 100.472 72.665  119.627 1.00 93.20  ? 317 LYS A N   1 
ATOM   2468 C  CA  . LYS A 1 317 ? 99.561  73.727  119.233 1.00 93.20  ? 317 LYS A CA  1 
ATOM   2469 C  C   . LYS A 1 317 ? 100.289 75.029  118.965 1.00 93.20  ? 317 LYS A C   1 
ATOM   2470 O  O   . LYS A 1 317 ? 99.646  76.040  118.682 1.00 93.20  ? 317 LYS A O   1 
ATOM   2471 C  CB  . LYS A 1 317 ? 98.504  73.950  120.313 1.00 93.20  ? 317 LYS A CB  1 
ATOM   2472 C  CG  . LYS A 1 317 ? 97.837  72.687  120.784 1.00 93.20  ? 317 LYS A CG  1 
ATOM   2473 C  CD  . LYS A 1 317 ? 96.914  72.138  119.721 1.00 93.20  ? 317 LYS A CD  1 
ATOM   2474 C  CE  . LYS A 1 317 ? 96.437  70.751  120.091 1.00 93.20  ? 317 LYS A CE  1 
ATOM   2475 N  NZ  . LYS A 1 317 ? 96.086  70.673  121.534 1.00 93.20  ? 317 LYS A NZ  1 
ATOM   2476 N  N   . HIS A 1 318 ? 101.611 75.030  119.054 1.00 88.66  ? 318 HIS A N   1 
ATOM   2477 C  CA  . HIS A 1 318 ? 102.389 76.245  118.913 1.00 88.66  ? 318 HIS A CA  1 
ATOM   2478 C  C   . HIS A 1 318 ? 103.273 76.231  117.683 1.00 88.66  ? 318 HIS A C   1 
ATOM   2479 O  O   . HIS A 1 318 ? 104.196 77.041  117.588 1.00 88.66  ? 318 HIS A O   1 
ATOM   2480 C  CB  . HIS A 1 318 ? 103.212 76.477  120.174 1.00 88.66  ? 318 HIS A CB  1 
ATOM   2481 C  CG  . HIS A 1 318 ? 102.383 76.871  121.351 1.00 88.66  ? 318 HIS A CG  1 
ATOM   2482 N  ND1 . HIS A 1 318 ? 101.635 75.966  122.069 1.00 88.66  ? 318 HIS A ND1 1 
ATOM   2483 C  CD2 . HIS A 1 318 ? 102.149 78.079  121.912 1.00 88.66  ? 318 HIS A CD2 1 
ATOM   2484 C  CE1 . HIS A 1 318 ? 100.996 76.595  123.037 1.00 88.66  ? 318 HIS A CE1 1 
ATOM   2485 N  NE2 . HIS A 1 318 ? 101.288 77.879  122.961 1.00 88.66  ? 318 HIS A NE2 1 
ATOM   2486 N  N   . PHE A 1 319 ? 103.016 75.330  116.746 1.00 85.99  ? 319 PHE A N   1 
ATOM   2487 C  CA  . PHE A 1 319 ? 103.601 75.385  115.419 1.00 85.99  ? 319 PHE A CA  1 
ATOM   2488 C  C   . PHE A 1 319 ? 102.479 75.558  114.410 1.00 85.99  ? 319 PHE A C   1 
ATOM   2489 O  O   . PHE A 1 319 ? 101.430 74.921  114.523 1.00 85.99  ? 319 PHE A O   1 
ATOM   2490 C  CB  . PHE A 1 319 ? 104.405 74.132  115.107 1.00 85.99  ? 319 PHE A CB  1 
ATOM   2491 C  CG  . PHE A 1 319 ? 105.408 74.312  114.013 1.00 85.99  ? 319 PHE A CG  1 
ATOM   2492 C  CD1 . PHE A 1 319 ? 105.217 73.723  112.784 1.00 85.99  ? 319 PHE A CD1 1 
ATOM   2493 C  CD2 . PHE A 1 319 ? 106.544 75.066  114.215 1.00 85.99  ? 319 PHE A CD2 1 
ATOM   2494 C  CE1 . PHE A 1 319 ? 106.135 73.878  111.780 1.00 85.99  ? 319 PHE A CE1 1 
ATOM   2495 C  CE2 . PHE A 1 319 ? 107.465 75.226  113.207 1.00 85.99  ? 319 PHE A CE2 1 
ATOM   2496 C  CZ  . PHE A 1 319 ? 107.260 74.621  111.994 1.00 85.99  ? 319 PHE A CZ  1 
ATOM   2497 N  N   . GLY A 1 320 ? 102.692 76.432  113.436 1.00 84.28  ? 320 GLY A N   1 
ATOM   2498 C  CA  . GLY A 1 320 ? 101.678 76.695  112.441 1.00 84.28  ? 320 GLY A CA  1 
ATOM   2499 C  C   . GLY A 1 320 ? 102.306 77.098  111.130 1.00 84.28  ? 320 GLY A C   1 
ATOM   2500 O  O   . GLY A 1 320 ? 103.523 77.040  110.965 1.00 84.28  ? 320 GLY A O   1 
ATOM   2501 N  N   . LEU A 1 321 ? 101.472 77.508  110.188 1.00 83.34  ? 321 LEU A N   1 
ATOM   2502 C  CA  . LEU A 1 321 ? 101.933 77.922  108.874 1.00 83.34  ? 321 LEU A CA  1 
ATOM   2503 C  C   . LEU A 1 321 ? 101.613 79.386  108.647 1.00 83.34  ? 321 LEU A C   1 
ATOM   2504 O  O   . LEU A 1 321 ? 100.569 79.878  109.078 1.00 83.34  ? 321 LEU A O   1 
ATOM   2505 C  CB  . LEU A 1 321 ? 101.286 77.094  107.770 1.00 83.34  ? 321 LEU A CB  1 
ATOM   2506 C  CG  . LEU A 1 321 ? 101.807 75.687  107.523 1.00 83.34  ? 321 LEU A CG  1 
ATOM   2507 C  CD1 . LEU A 1 321 ? 101.233 75.191  106.227 1.00 83.34  ? 321 LEU A CD1 1 
ATOM   2508 C  CD2 . LEU A 1 321 ? 103.308 75.684  107.472 1.00 83.34  ? 321 LEU A CD2 1 
ATOM   2509 N  N   . LEU A 1 322 ? 102.513 80.073  107.966 1.00 79.44  ? 322 LEU A N   1 
ATOM   2510 C  CA  . LEU A 1 322 ? 102.279 81.427  107.503 1.00 79.44  ? 322 LEU A CA  1 
ATOM   2511 C  C   . LEU A 1 322 ? 102.165 81.389  105.990 1.00 79.44  ? 322 LEU A C   1 
ATOM   2512 O  O   . LEU A 1 322 ? 103.016 80.805  105.317 1.00 79.44  ? 322 LEU A O   1 
ATOM   2513 C  CB  . LEU A 1 322 ? 103.409 82.351  107.945 1.00 79.44  ? 322 LEU A CB  1 
ATOM   2514 C  CG  . LEU A 1 322 ? 103.175 83.853  107.935 1.00 79.44  ? 322 LEU A CG  1 
ATOM   2515 C  CD1 . LEU A 1 322 ? 103.863 84.464  109.113 1.00 79.44  ? 322 LEU A CD1 1 
ATOM   2516 C  CD2 . LEU A 1 322 ? 103.725 84.441  106.680 1.00 79.44  ? 322 LEU A CD2 1 
ATOM   2517 N  N   . LEU A 1 323 ? 101.119 81.998  105.461 1.00 81.93  ? 323 LEU A N   1 
ATOM   2518 C  CA  . LEU A 1 323 ? 100.847 81.968  104.035 1.00 81.93  ? 323 LEU A CA  1 
ATOM   2519 C  C   . LEU A 1 323 ? 101.142 83.327  103.423 1.00 81.93  ? 323 LEU A C   1 
ATOM   2520 O  O   . LEU A 1 323 ? 100.564 84.336  103.820 1.00 81.93  ? 323 LEU A O   1 
ATOM   2521 C  CB  . LEU A 1 323 ? 99.396  81.579  103.779 1.00 81.93  ? 323 LEU A CB  1 
ATOM   2522 C  CG  . LEU A 1 323 ? 99.109  80.844  102.483 1.00 81.93  ? 323 LEU A CG  1 
ATOM   2523 C  CD1 . LEU A 1 323 ? 99.811  79.516  102.503 1.00 81.93  ? 323 LEU A CD1 1 
ATOM   2524 C  CD2 . LEU A 1 323 ? 97.625  80.652  102.330 1.00 81.93  ? 323 LEU A CD2 1 
ATOM   2525 N  N   . ASP A 1 324 ? 102.041 83.350  102.456 1.00 86.06  ? 324 ASP A N   1 
ATOM   2526 C  CA  . ASP A 1 324 ? 102.338 84.561  101.713 1.00 86.06  ? 324 ASP A CA  1 
ATOM   2527 C  C   . ASP A 1 324 ? 101.586 84.502  100.394 1.00 86.06  ? 324 ASP A C   1 
ATOM   2528 O  O   . ASP A 1 324 ? 101.731 83.541  99.637  1.00 86.06  ? 324 ASP A O   1 
ATOM   2529 C  CB  . ASP A 1 324 ? 103.843 84.689  101.480 1.00 86.06  ? 324 ASP A CB  1 
ATOM   2530 C  CG  . ASP A 1 324 ? 104.262 86.078  101.064 1.00 86.06  ? 324 ASP A CG  1 
ATOM   2531 O  OD1 . ASP A 1 324 ? 104.782 86.830  101.910 1.00 86.06  ? 324 ASP A OD1 1 
ATOM   2532 O  OD2 . ASP A 1 324 ? 104.099 86.412  99.879  1.00 86.06  ? 324 ASP A OD2 1 
ATOM   2533 N  N   . THR A 1 325 ? 100.784 85.528  100.113 1.00 86.03  ? 325 THR A N   1 
ATOM   2534 C  CA  . THR A 1 325 ? 99.928  85.518  98.932  1.00 86.03  ? 325 THR A CA  1 
ATOM   2535 C  C   . THR A 1 325 ? 100.660 85.838  97.639  1.00 86.03  ? 325 THR A C   1 
ATOM   2536 O  O   . THR A 1 325 ? 100.003 86.026  96.614  1.00 86.03  ? 325 THR A O   1 
ATOM   2537 C  CB  . THR A 1 325 ? 98.767  86.498  99.091  1.00 86.03  ? 325 THR A CB  1 
ATOM   2538 O  OG1 . THR A 1 325 ? 99.252  87.840  98.976  1.00 86.03  ? 325 THR A OG1 1 
ATOM   2539 C  CG2 . THR A 1 325 ? 98.091  86.317  100.415 1.00 86.03  ? 325 THR A CG2 1 
ATOM   2540 N  N   . GLY A 1 326 ? 101.991 85.900  97.648  1.00 87.70  ? 326 GLY A N   1 
ATOM   2541 C  CA  . GLY A 1 326 ? 102.726 86.007  96.404  1.00 87.70  ? 326 GLY A CA  1 
ATOM   2542 C  C   . GLY A 1 326 ? 102.735 84.722  95.608  1.00 87.70  ? 326 GLY A C   1 
ATOM   2543 O  O   . GLY A 1 326 ? 103.099 84.728  94.430  1.00 87.70  ? 326 GLY A O   1 
ATOM   2544 N  N   . ILE A 1 327 ? 102.340 83.611  96.228  1.00 88.54  ? 327 ILE A N   1 
ATOM   2545 C  CA  . ILE A 1 327 ? 102.253 82.351  95.513  1.00 88.54  ? 327 ILE A CA  1 
ATOM   2546 C  C   . ILE A 1 327 ? 101.044 82.302  94.590  1.00 88.54  ? 327 ILE A C   1 
ATOM   2547 O  O   . ILE A 1 327 ? 101.015 81.492  93.662  1.00 88.54  ? 327 ILE A O   1 
ATOM   2548 C  CB  . ILE A 1 327 ? 102.241 81.183  96.515  1.00 88.54  ? 327 ILE A CB  1 
ATOM   2549 C  CG1 . ILE A 1 327 ? 100.978 81.208  97.364  1.00 88.54  ? 327 ILE A CG1 1 
ATOM   2550 C  CG2 . ILE A 1 327 ? 103.444 81.263  97.411  1.00 88.54  ? 327 ILE A CG2 1 
ATOM   2551 C  CD1 . ILE A 1 327 ? 100.886 80.079  98.347  1.00 88.54  ? 327 ILE A CD1 1 
ATOM   2552 N  N   . PHE A 1 328 ? 100.053 83.160  94.798  1.00 89.08  ? 328 PHE A N   1 
ATOM   2553 C  CA  . PHE A 1 328 ? 98.870  83.197  93.955  1.00 89.08  ? 328 PHE A CA  1 
ATOM   2554 C  C   . PHE A 1 328 ? 99.009  84.148  92.784  1.00 89.08  ? 328 PHE A C   1 
ATOM   2555 O  O   . PHE A 1 328 ? 98.049  84.316  92.034  1.00 89.08  ? 328 PHE A O   1 
ATOM   2556 C  CB  . PHE A 1 328 ? 97.649  83.593  94.778  1.00 89.08  ? 328 PHE A CB  1 
ATOM   2557 C  CG  . PHE A 1 328 ? 97.409  82.713  95.952  1.00 89.08  ? 328 PHE A CG  1 
ATOM   2558 C  CD1 . PHE A 1 328 ? 97.171  81.366  95.781  1.00 89.08  ? 328 PHE A CD1 1 
ATOM   2559 C  CD2 . PHE A 1 328 ? 97.424  83.229  97.225  1.00 89.08  ? 328 PHE A CD2 1 
ATOM   2560 C  CE1 . PHE A 1 328 ? 96.952  80.552  96.859  1.00 89.08  ? 328 PHE A CE1 1 
ATOM   2561 C  CE2 . PHE A 1 328 ? 97.203  82.418  98.308  1.00 89.08  ? 328 PHE A CE2 1 
ATOM   2562 C  CZ  . PHE A 1 328 ? 96.967  81.079  98.122  1.00 89.08  ? 328 PHE A CZ  1 
ATOM   2563 N  N   . GLN A 1 329 ? 100.177 84.763  92.614  1.00 94.27  ? 329 GLN A N   1 
ATOM   2564 C  CA  . GLN A 1 329 ? 100.386 85.755  91.569  1.00 94.27  ? 329 GLN A CA  1 
ATOM   2565 C  C   . GLN A 1 329 ? 100.309 85.122  90.185  1.00 94.27  ? 329 GLN A C   1 
ATOM   2566 O  O   . GLN A 1 329 ? 100.949 84.104  89.914  1.00 94.27  ? 329 GLN A O   1 
ATOM   2567 C  CB  . GLN A 1 329 ? 101.741 86.424  91.770  1.00 94.27  ? 329 GLN A CB  1 
ATOM   2568 C  CG  . GLN A 1 329 ? 102.151 87.343  90.658  1.00 94.27  ? 329 GLN A CG  1 
ATOM   2569 C  CD  . GLN A 1 329 ? 103.635 87.558  90.616  1.00 94.27  ? 329 GLN A CD  1 
ATOM   2570 O  OE1 . GLN A 1 329 ? 104.350 87.170  91.530  1.00 94.27  ? 329 GLN A OE1 1 
ATOM   2571 N  NE2 . GLN A 1 329 ? 104.111 88.179  89.551  1.00 94.27  ? 329 GLN A NE2 1 
ATOM   2572 N  N   . ASP A 1 330 ? 99.506  85.724  89.312  1.00 94.74  ? 330 ASP A N   1 
ATOM   2573 C  CA  . ASP A 1 330 ? 99.227  85.159  88.001  1.00 94.74  ? 330 ASP A CA  1 
ATOM   2574 C  C   . ASP A 1 330 ? 99.733  86.018  86.854  1.00 94.74  ? 330 ASP A C   1 
ATOM   2575 O  O   . ASP A 1 330 ? 99.859  85.518  85.733  1.00 94.74  ? 330 ASP A O   1 
ATOM   2576 C  CB  . ASP A 1 330 ? 97.720  84.914  87.844  1.00 94.74  ? 330 ASP A CB  1 
ATOM   2577 C  CG  . ASP A 1 330 ? 96.908  86.182  87.910  1.00 94.74  ? 330 ASP A CG  1 
ATOM   2578 O  OD1 . ASP A 1 330 ? 97.382  87.175  88.488  1.00 94.74  ? 330 ASP A OD1 1 
ATOM   2579 O  OD2 . ASP A 1 330 ? 95.778  86.183  87.383  1.00 94.74  ? 330 ASP A OD2 1 
ATOM   2580 N  N   . ARG A 1 331 ? 100.018 87.288  87.094  1.00 94.53  ? 331 ARG A N   1 
ATOM   2581 C  CA  . ARG A 1 331 ? 100.551 88.158  86.064  1.00 94.53  ? 331 ARG A CA  1 
ATOM   2582 C  C   . ARG A 1 331 ? 101.947 88.615  86.468  1.00 94.53  ? 331 ARG A C   1 
ATOM   2583 O  O   . ARG A 1 331 ? 102.229 88.750  87.659  1.00 94.53  ? 331 ARG A O   1 
ATOM   2584 C  CB  . ARG A 1 331 ? 99.626  89.356  85.852  1.00 94.53  ? 331 ARG A CB  1 
ATOM   2585 C  CG  . ARG A 1 331 ? 98.310  88.973  85.214  1.00 94.53  ? 331 ARG A CG  1 
ATOM   2586 C  CD  . ARG A 1 331 ? 97.355  90.146  85.124  1.00 94.53  ? 331 ARG A CD  1 
ATOM   2587 N  NE  . ARG A 1 331 ? 97.156  90.808  86.408  1.00 94.53  ? 331 ARG A NE  1 
ATOM   2588 C  CZ  . ARG A 1 331 ? 96.336  90.379  87.360  1.00 94.53  ? 331 ARG A CZ  1 
ATOM   2589 N  NH1 . ARG A 1 331 ? 95.624  89.277  87.188  1.00 94.53  ? 331 ARG A NH1 1 
ATOM   2590 N  NH2 . ARG A 1 331 ? 96.226  91.055  88.489  1.00 94.53  ? 331 ARG A NH2 1 
ATOM   2591 N  N   . PRO A 1 332 ? 102.847 88.835  85.510  1.00 99.85  ? 332 PRO A N   1 
ATOM   2592 C  CA  . PRO A 1 332 ? 104.251 89.056  85.865  1.00 99.85  ? 332 PRO A CA  1 
ATOM   2593 C  C   . PRO A 1 332 ? 104.513 90.422  86.479  1.00 99.85  ? 332 PRO A C   1 
ATOM   2594 O  O   . PRO A 1 332 ? 103.878 91.423  86.146  1.00 99.85  ? 332 PRO A O   1 
ATOM   2595 C  CB  . PRO A 1 332 ? 104.976 88.914  84.526  1.00 99.85  ? 332 PRO A CB  1 
ATOM   2596 C  CG  . PRO A 1 332 ? 103.962 89.264  83.532  1.00 99.85  ? 332 PRO A CG  1 
ATOM   2597 C  CD  . PRO A 1 332 ? 102.687 88.705  84.053  1.00 99.85  ? 332 PRO A CD  1 
ATOM   2598 N  N   . ILE A 1 333 ? 105.463 90.434  87.400  1.00 104.24 ? 333 ILE A N   1 
ATOM   2599 C  CA  . ILE A 1 333 ? 106.039 91.675  87.920  1.00 104.24 ? 333 ILE A CA  1 
ATOM   2600 C  C   . ILE A 1 333 ? 106.803 92.357  86.793  1.00 104.24 ? 333 ILE A C   1 
ATOM   2601 O  O   . ILE A 1 333 ? 107.575 91.684  86.094  1.00 104.24 ? 333 ILE A O   1 
ATOM   2602 C  CB  . ILE A 1 333 ? 106.950 91.366  89.104  1.00 104.24 ? 333 ILE A CB  1 
ATOM   2603 C  CG1 . ILE A 1 333 ? 106.121 90.876  90.288  1.00 104.24 ? 333 ILE A CG1 1 
ATOM   2604 C  CG2 . ILE A 1 333 ? 107.779 92.566  89.510  1.00 104.24 ? 333 ILE A CG2 1 
ATOM   2605 C  CD1 . ILE A 1 333 ? 106.921 90.136  91.322  1.00 104.24 ? 333 ILE A CD1 1 
ATOM   2606 N  N   . PRO A 1 334 ? 106.596 93.656  86.558  1.00 113.83 ? 334 PRO A N   1 
ATOM   2607 C  CA  . PRO A 1 334 ? 107.172 94.300  85.371  1.00 113.83 ? 334 PRO A CA  1 
ATOM   2608 C  C   . PRO A 1 334 ? 108.687 94.380  85.435  1.00 113.83 ? 334 PRO A C   1 
ATOM   2609 O  O   . PRO A 1 334 ? 109.286 94.343  86.510  1.00 113.83 ? 334 PRO A O   1 
ATOM   2610 C  CB  . PRO A 1 334 ? 106.543 95.696  85.385  1.00 113.83 ? 334 PRO A CB  1 
ATOM   2611 C  CG  . PRO A 1 334 ? 105.343 95.566  86.230  1.00 113.83 ? 334 PRO A CG  1 
ATOM   2612 C  CD  . PRO A 1 334 ? 105.689 94.565  87.273  1.00 113.83 ? 334 PRO A CD  1 
ATOM   2613 N  N   . LEU A 1 335 ? 109.300 94.469  84.260  1.00 128.12 ? 335 LEU A N   1 
ATOM   2614 C  CA  . LEU A 1 335 ? 110.750 94.475  84.170  1.00 128.12 ? 335 LEU A CA  1 
ATOM   2615 C  C   . LEU A 1 335 ? 111.317 95.782  84.699  1.00 128.12 ? 335 LEU A C   1 
ATOM   2616 O  O   . LEU A 1 335 ? 110.822 96.868  84.385  1.00 128.12 ? 335 LEU A O   1 
ATOM   2617 C  CB  . LEU A 1 335 ? 111.194 94.263  82.727  1.00 128.12 ? 335 LEU A CB  1 
ATOM   2618 C  CG  . LEU A 1 335 ? 111.091 92.828  82.223  1.00 128.12 ? 335 LEU A CG  1 
ATOM   2619 C  CD1 . LEU A 1 335 ? 111.065 92.801  80.707  1.00 128.12 ? 335 LEU A CD1 1 
ATOM   2620 C  CD2 . LEU A 1 335 ? 112.241 92.004  82.759  1.00 128.12 ? 335 LEU A CD2 1 
ATOM   2621 N  N   . LYS A 1 336 ? 112.344 95.659  85.529  1.00 136.40 ? 336 LYS A N   1 
ATOM   2622 C  CA  . LYS A 1 336 ? 113.091 96.807  86.001  1.00 136.40 ? 336 LYS A CA  1 
ATOM   2623 C  C   . LYS A 1 336 ? 113.776 97.485  84.816  1.00 136.40 ? 336 LYS A C   1 
ATOM   2624 O  O   . LYS A 1 336 ? 114.176 96.809  83.865  1.00 136.40 ? 336 LYS A O   1 
ATOM   2625 C  CB  . LYS A 1 336 ? 114.107 96.347  87.046  1.00 136.40 ? 336 LYS A CB  1 
ATOM   2626 C  CG  . LYS A 1 336 ? 114.933 97.425  87.703  1.00 136.40 ? 336 LYS A CG  1 
ATOM   2627 C  CD  . LYS A 1 336 ? 115.708 96.847  88.866  1.00 136.40 ? 336 LYS A CD  1 
ATOM   2628 C  CE  . LYS A 1 336 ? 116.823 95.935  88.390  1.00 136.40 ? 336 LYS A CE  1 
ATOM   2629 N  NZ  . LYS A 1 336 ? 117.652 95.450  89.526  1.00 136.40 ? 336 LYS A NZ  1 
ATOM   2630 N  N   . PRO A 1 337 ? 113.849 98.819  84.804  1.00 140.29 ? 337 PRO A N   1 
ATOM   2631 C  CA  . PRO A 1 337 ? 114.533 99.503  83.698  1.00 140.29 ? 337 PRO A CA  1 
ATOM   2632 C  C   . PRO A 1 337 ? 116.019 99.179  83.664  1.00 140.29 ? 337 PRO A C   1 
ATOM   2633 O  O   . PRO A 1 337 ? 116.739 99.357  84.649  1.00 140.29 ? 337 PRO A O   1 
ATOM   2634 C  CB  . PRO A 1 337 ? 114.285 100.989 83.992  1.00 140.29 ? 337 PRO A CB  1 
ATOM   2635 C  CG  . PRO A 1 337 ? 113.839 101.040 85.424  1.00 140.29 ? 337 PRO A CG  1 
ATOM   2636 C  CD  . PRO A 1 337 ? 113.091 99.770  85.633  1.00 140.29 ? 337 PRO A CD  1 
ATOM   2637 N  N   . GLY A 1 338 ? 116.468 98.682  82.512  1.00 140.75 ? 338 GLY A N   1 
ATOM   2638 C  CA  . GLY A 1 338 ? 117.848 98.297  82.327  1.00 140.75 ? 338 GLY A CA  1 
ATOM   2639 C  C   . GLY A 1 338 ? 118.097 96.817  82.137  1.00 140.75 ? 338 GLY A C   1 
ATOM   2640 O  O   . GLY A 1 338 ? 119.220 96.439  81.780  1.00 140.75 ? 338 GLY A O   1 
ATOM   2641 N  N   . GLU A 1 339 ? 117.102 95.963  82.364  1.00 137.63 ? 339 GLU A N   1 
ATOM   2642 C  CA  . GLU A 1 339 ? 117.268 94.531  82.166  1.00 137.63 ? 339 GLU A CA  1 
ATOM   2643 C  C   . GLU A 1 339 ? 116.442 94.063  80.971  1.00 137.63 ? 339 GLU A C   1 
ATOM   2644 O  O   . GLU A 1 339 ? 115.385 94.624  80.662  1.00 137.63 ? 339 GLU A O   1 
ATOM   2645 C  CB  . GLU A 1 339 ? 116.887 93.751  83.431  1.00 137.63 ? 339 GLU A CB  1 
ATOM   2646 C  CG  . GLU A 1 339 ? 115.414 93.797  83.807  1.00 137.63 ? 339 GLU A CG  1 
ATOM   2647 C  CD  . GLU A 1 339 ? 115.111 93.098  85.118  1.00 137.63 ? 339 GLU A CD  1 
ATOM   2648 O  OE1 . GLU A 1 339 ? 116.054 92.579  85.751  1.00 137.63 ? 339 GLU A OE1 1 
ATOM   2649 O  OE2 . GLU A 1 339 ? 113.928 93.074  85.518  1.00 137.63 ? 339 GLU A OE2 1 
ATOM   2650 N  N   . LEU A 1 340 ? 116.963 93.054  80.277  1.00 138.39 ? 340 LEU A N   1 
ATOM   2651 C  CA  . LEU A 1 340 ? 116.259 92.329  79.238  1.00 138.39 ? 340 LEU A CA  1 
ATOM   2652 C  C   . LEU A 1 340 ? 115.780 90.997  79.810  1.00 138.39 ? 340 LEU A C   1 
ATOM   2653 O  O   . LEU A 1 340 ? 116.275 90.574  80.858  1.00 138.39 ? 340 LEU A O   1 
ATOM   2654 C  CB  . LEU A 1 340 ? 117.173 92.124  78.018  1.00 138.39 ? 340 LEU A CB  1 
ATOM   2655 C  CG  . LEU A 1 340 ? 118.360 91.160  78.013  1.00 138.39 ? 340 LEU A CG  1 
ATOM   2656 C  CD1 . LEU A 1 340 ? 118.671 90.757  76.587  1.00 138.39 ? 340 LEU A CD1 1 
ATOM   2657 C  CD2 . LEU A 1 340 ? 119.594 91.797  78.622  1.00 138.39 ? 340 LEU A CD2 1 
ATOM   2658 N  N   . PRO A 1 341 ? 114.777 90.349  79.196  1.00 138.65 ? 341 PRO A N   1 
ATOM   2659 C  CA  . PRO A 1 341 ? 114.268 89.092  79.774  1.00 138.65 ? 341 PRO A CA  1 
ATOM   2660 C  C   . PRO A 1 341 ? 115.274 87.952  79.753  1.00 138.65 ? 341 PRO A C   1 
ATOM   2661 O  O   . PRO A 1 341 ? 115.865 87.645  78.713  1.00 138.65 ? 341 PRO A O   1 
ATOM   2662 C  CB  . PRO A 1 341 ? 113.050 88.775  78.899  1.00 138.65 ? 341 PRO A CB  1 
ATOM   2663 C  CG  . PRO A 1 341 ? 112.587 90.087  78.424  1.00 138.65 ? 341 PRO A CG  1 
ATOM   2664 C  CD  . PRO A 1 341 ? 113.828 90.896  78.205  1.00 138.65 ? 341 PRO A CD  1 
ATOM   2665 N  N   . GLY A 1 342 ? 115.468 87.314  80.909  1.00 135.23 ? 342 GLY A N   1 
ATOM   2666 C  CA  . GLY A 1 342 ? 116.312 86.138  80.973  1.00 135.23 ? 342 GLY A CA  1 
ATOM   2667 C  C   . GLY A 1 342 ? 117.233 86.081  82.176  1.00 135.23 ? 342 GLY A C   1 
ATOM   2668 O  O   . GLY A 1 342 ? 117.522 84.989  82.673  1.00 135.23 ? 342 GLY A O   1 
ATOM   2669 N  N   . GLN A 1 343 ? 117.703 87.228  82.671  1.00 133.01 ? 343 GLN A N   1 
ATOM   2670 C  CA  . GLN A 1 343 ? 118.664 87.188  83.769  1.00 133.01 ? 343 GLN A CA  1 
ATOM   2671 C  C   . GLN A 1 343 ? 117.971 87.277  85.121  1.00 133.01 ? 343 GLN A C   1 
ATOM   2672 O  O   . GLN A 1 343 ? 118.586 87.016  86.161  1.00 133.01 ? 343 GLN A O   1 
ATOM   2673 C  CB  . GLN A 1 343 ? 119.693 88.308  83.631  1.00 133.01 ? 343 GLN A CB  1 
ATOM   2674 C  CG  . GLN A 1 343 ? 119.098 89.683  83.517  1.00 133.01 ? 343 GLN A CG  1 
ATOM   2675 C  CD  . GLN A 1 343 ? 119.076 90.175  82.095  1.00 133.01 ? 343 GLN A CD  1 
ATOM   2676 O  OE1 . GLN A 1 343 ? 119.157 89.391  81.151  1.00 133.01 ? 343 GLN A OE1 1 
ATOM   2677 N  NE2 . GLN A 1 343 ? 118.971 91.486  81.930  1.00 133.01 ? 343 GLN A NE2 1 
ATOM   2678 N  N   . ARG A 1 344 ? 116.701 87.654  85.132  1.00 121.10 ? 344 ARG A N   1 
ATOM   2679 C  CA  . ARG A 1 344 ? 115.946 87.581  86.370  1.00 121.10 ? 344 ARG A CA  1 
ATOM   2680 C  C   . ARG A 1 344 ? 115.326 86.193  86.504  1.00 121.10 ? 344 ARG A C   1 
ATOM   2681 O  O   . ARG A 1 344 ? 115.104 85.511  85.496  1.00 121.10 ? 344 ARG A O   1 
ATOM   2682 C  CB  . ARG A 1 344 ? 114.880 88.680  86.409  1.00 121.10 ? 344 ARG A CB  1 
ATOM   2683 C  CG  . ARG A 1 344 ? 113.546 88.332  85.793  1.00 121.10 ? 344 ARG A CG  1 
ATOM   2684 C  CD  . ARG A 1 344 ? 112.554 89.449  86.027  1.00 121.10 ? 344 ARG A CD  1 
ATOM   2685 N  NE  . ARG A 1 344 ? 111.226 89.116  85.536  1.00 121.10 ? 344 ARG A NE  1 
ATOM   2686 C  CZ  . ARG A 1 344 ? 110.141 89.825  85.810  1.00 121.10 ? 344 ARG A CZ  1 
ATOM   2687 N  NH1 . ARG A 1 344 ? 110.234 90.901  86.574  1.00 121.10 ? 344 ARG A NH1 1 
ATOM   2688 N  NH2 . ARG A 1 344 ? 108.967 89.459  85.322  1.00 121.10 ? 344 ARG A NH2 1 
ATOM   2689 N  N   . PRO A 1 345 ? 115.101 85.712  87.729  1.00 116.62 ? 345 PRO A N   1 
ATOM   2690 C  CA  . PRO A 1 345 ? 114.549 84.363  87.895  1.00 116.62 ? 345 PRO A CA  1 
ATOM   2691 C  C   . PRO A 1 345 ? 113.106 84.274  87.425  1.00 116.62 ? 345 PRO A C   1 
ATOM   2692 O  O   . PRO A 1 345 ? 112.379 85.266  87.380  1.00 116.62 ? 345 PRO A O   1 
ATOM   2693 C  CB  . PRO A 1 345 ? 114.664 84.115  89.400  1.00 116.62 ? 345 PRO A CB  1 
ATOM   2694 C  CG  . PRO A 1 345 ? 115.728 85.034  89.855  1.00 116.62 ? 345 PRO A CG  1 
ATOM   2695 C  CD  . PRO A 1 345 ? 115.601 86.250  89.005  1.00 116.62 ? 345 PRO A CD  1 
ATOM   2696 N  N   . ALA A 1 346 ? 112.700 83.057  87.067  1.00 111.14 ? 346 ALA A N   1 
ATOM   2697 C  CA  . ALA A 1 346 ? 111.433 82.861  86.375  1.00 111.14 ? 346 ALA A CA  1 
ATOM   2698 C  C   . ALA A 1 346 ? 110.240 82.827  87.318  1.00 111.14 ? 346 ALA A C   1 
ATOM   2699 O  O   . ALA A 1 346 ? 109.100 82.738  86.852  1.00 111.14 ? 346 ALA A O   1 
ATOM   2700 C  CB  . ALA A 1 346 ? 111.479 81.576  85.552  1.00 111.14 ? 346 ALA A CB  1 
ATOM   2701 N  N   . PHE A 1 347 ? 110.460 82.885  88.628  1.00 107.03 ? 347 PHE A N   1 
ATOM   2702 C  CA  . PHE A 1 347 ? 109.339 82.955  89.551  1.00 107.03 ? 347 PHE A CA  1 
ATOM   2703 C  C   . PHE A 1 347 ? 108.854 84.377  89.772  1.00 107.03 ? 347 PHE A C   1 
ATOM   2704 O  O   . PHE A 1 347 ? 107.863 84.573  90.479  1.00 107.03 ? 347 PHE A O   1 
ATOM   2705 C  CB  . PHE A 1 347 ? 109.696 82.297  90.885  1.00 107.03 ? 347 PHE A CB  1 
ATOM   2706 C  CG  . PHE A 1 347 ? 110.574 83.131  91.774  1.00 107.03 ? 347 PHE A CG  1 
ATOM   2707 C  CD1 . PHE A 1 347 ? 110.038 83.849  92.834  1.00 107.03 ? 347 PHE A CD1 1 
ATOM   2708 C  CD2 . PHE A 1 347 ? 111.941 83.160  91.582  1.00 107.03 ? 347 PHE A CD2 1 
ATOM   2709 C  CE1 . PHE A 1 347 ? 110.842 84.606  93.652  1.00 107.03 ? 347 PHE A CE1 1 
ATOM   2710 C  CE2 . PHE A 1 347 ? 112.752 83.911  92.406  1.00 107.03 ? 347 PHE A CE2 1 
ATOM   2711 C  CZ  . PHE A 1 347 ? 112.201 84.635  93.440  1.00 107.03 ? 347 PHE A CZ  1 
ATOM   2712 N  N   . LEU A 1 348 ? 109.521 85.372  89.192  1.00 109.17 ? 348 LEU A N   1 
ATOM   2713 C  CA  . LEU A 1 348 ? 109.009 86.733  89.215  1.00 109.17 ? 348 LEU A CA  1 
ATOM   2714 C  C   . LEU A 1 348 ? 107.926 86.970  88.175  1.00 109.17 ? 348 LEU A C   1 
ATOM   2715 O  O   . LEU A 1 348 ? 107.387 88.077  88.105  1.00 109.17 ? 348 LEU A O   1 
ATOM   2716 C  CB  . LEU A 1 348 ? 110.146 87.733  89.017  1.00 109.17 ? 348 LEU A CB  1 
ATOM   2717 C  CG  . LEU A 1 348 ? 111.330 87.575  89.966  1.00 109.17 ? 348 LEU A CG  1 
ATOM   2718 C  CD1 . LEU A 1 348 ? 112.339 88.671  89.721  1.00 109.17 ? 348 LEU A CD1 1 
ATOM   2719 C  CD2 . LEU A 1 348 ? 110.868 87.606  91.407  1.00 109.17 ? 348 LEU A CD2 1 
ATOM   2720 N  N   . ASP A 1 349 ? 107.603 85.966  87.371  1.00 107.89 ? 349 ASP A N   1 
ATOM   2721 C  CA  . ASP A 1 349 ? 106.413 85.964  86.541  1.00 107.89 ? 349 ASP A CA  1 
ATOM   2722 C  C   . ASP A 1 349 ? 105.216 85.369  87.263  1.00 107.89 ? 349 ASP A C   1 
ATOM   2723 O  O   . ASP A 1 349 ? 104.137 85.270  86.673  1.00 107.89 ? 349 ASP A O   1 
ATOM   2724 C  CB  . ASP A 1 349 ? 106.679 85.178  85.260  1.00 107.89 ? 349 ASP A CB  1 
ATOM   2725 C  CG  . ASP A 1 349 ? 107.776 85.790  84.426  1.00 107.89 ? 349 ASP A CG  1 
ATOM   2726 O  OD1 . ASP A 1 349 ? 107.955 87.023  84.490  1.00 107.89 ? 349 ASP A OD1 1 
ATOM   2727 O  OD2 . ASP A 1 349 ? 108.470 85.038  83.714  1.00 107.89 ? 349 ASP A OD2 1 
ATOM   2728 N  N   . GLY A 1 350 ? 105.382 84.967  88.511  1.00 101.71 ? 350 GLY A N   1 
ATOM   2729 C  CA  . GLY A 1 350 ? 104.315 84.337  89.264  1.00 101.71 ? 350 GLY A CA  1 
ATOM   2730 C  C   . GLY A 1 350 ? 104.263 82.843  89.037  1.00 101.71 ? 350 GLY A C   1 
ATOM   2731 O  O   . GLY A 1 350 ? 104.350 82.349  87.915  1.00 101.71 ? 350 GLY A O   1 
ATOM   2732 N  N   . ILE A 1 351 ? 104.123 82.103  90.139  1.00 97.27  ? 351 ILE A N   1 
ATOM   2733 C  CA  . ILE A 1 351 ? 104.064 80.648  90.057  1.00 97.27  ? 351 ILE A CA  1 
ATOM   2734 C  C   . ILE A 1 351 ? 102.646 80.128  89.908  1.00 97.27  ? 351 ILE A C   1 
ATOM   2735 O  O   . ILE A 1 351 ? 102.475 78.934  89.620  1.00 97.27  ? 351 ILE A O   1 
ATOM   2736 C  CB  . ILE A 1 351 ? 104.725 79.987  91.279  1.00 97.27  ? 351 ILE A CB  1 
ATOM   2737 C  CG1 . ILE A 1 351 ? 104.047 80.438  92.564  1.00 97.27  ? 351 ILE A CG1 1 
ATOM   2738 C  CG2 . ILE A 1 351 ? 106.193 80.322  91.317  1.00 97.27  ? 351 ILE A CG2 1 
ATOM   2739 C  CD1 . ILE A 1 351 ? 104.477 79.658  93.767  1.00 97.27  ? 351 ILE A CD1 1 
ATOM   2740 N  N   . HIS A 1 352 ? 101.638 80.979  90.117  1.00 98.36  ? 352 HIS A N   1 
ATOM   2741 C  CA  . HIS A 1 352 ? 100.234 80.724  89.777  1.00 98.36  ? 352 HIS A CA  1 
ATOM   2742 C  C   . HIS A 1 352 ? 99.665  79.518  90.519  1.00 98.36  ? 352 HIS A C   1 
ATOM   2743 O  O   . HIS A 1 352 ? 99.187  78.559  89.915  1.00 98.36  ? 352 HIS A O   1 
ATOM   2744 C  CB  . HIS A 1 352 ? 100.054 80.549  88.267  1.00 98.36  ? 352 HIS A CB  1 
ATOM   2745 C  CG  . HIS A 1 352 ? 98.683  80.892  87.775  1.00 98.36  ? 352 HIS A CG  1 
ATOM   2746 N  ND1 . HIS A 1 352 ? 97.536  80.373  88.336  1.00 98.36  ? 352 HIS A ND1 1 
ATOM   2747 C  CD2 . HIS A 1 352 ? 98.277  81.661  86.739  1.00 98.36  ? 352 HIS A CD2 1 
ATOM   2748 C  CE1 . HIS A 1 352 ? 96.482  80.841  87.693  1.00 98.36  ? 352 HIS A CE1 1 
ATOM   2749 N  NE2 . HIS A 1 352 ? 96.904  81.622  86.717  1.00 98.36  ? 352 HIS A NE2 1 
ATOM   2750 N  N   . VAL A 1 353 ? 99.716  79.568  91.847  1.00 95.62  ? 353 VAL A N   1 
ATOM   2751 C  CA  . VAL A 1 353 ? 99.045  78.548  92.637  1.00 95.62  ? 353 VAL A CA  1 
ATOM   2752 C  C   . VAL A 1 353 ? 97.546  78.788  92.564  1.00 95.62  ? 353 VAL A C   1 
ATOM   2753 O  O   . VAL A 1 353 ? 97.075  79.921  92.716  1.00 95.62  ? 353 VAL A O   1 
ATOM   2754 C  CB  . VAL A 1 353 ? 99.556  78.567  94.088  1.00 95.62  ? 353 VAL A CB  1 
ATOM   2755 C  CG1 . VAL A 1 353 ? 98.736  77.661  94.978  1.00 95.62  ? 353 VAL A CG1 1 
ATOM   2756 C  CG2 . VAL A 1 353 ? 101.002 78.153  94.130  1.00 95.62  ? 353 VAL A CG2 1 
ATOM   2757 N  N   . ASP A 1 354 ? 96.797  77.734  92.266  1.00 98.00  ? 354 ASP A N   1 
ATOM   2758 C  CA  . ASP A 1 354 ? 95.350  77.825  92.297  1.00 98.00  ? 354 ASP A CA  1 
ATOM   2759 C  C   . ASP A 1 354 ? 94.884  78.047  93.732  1.00 98.00  ? 354 ASP A C   1 
ATOM   2760 O  O   . ASP A 1 354 ? 95.355  77.364  94.645  1.00 98.00  ? 354 ASP A O   1 
ATOM   2761 C  CB  . ASP A 1 354 ? 94.730  76.552  91.735  1.00 98.00  ? 354 ASP A CB  1 
ATOM   2762 C  CG  . ASP A 1 354 ? 93.235  76.651  91.585  1.00 98.00  ? 354 ASP A CG  1 
ATOM   2763 O  OD1 . ASP A 1 354 ? 92.768  77.567  90.883  1.00 98.00  ? 354 ASP A OD1 1 
ATOM   2764 O  OD2 . ASP A 1 354 ? 92.524  75.809  92.166  1.00 98.00  ? 354 ASP A OD2 1 
ATOM   2765 N  N   . PRO A 1 355 ? 93.978  79.000  93.967  1.00 94.95  ? 355 PRO A N   1 
ATOM   2766 C  CA  . PRO A 1 355 ? 93.605  79.336  95.350  1.00 94.95  ? 355 PRO A CA  1 
ATOM   2767 C  C   . PRO A 1 355 ? 92.795  78.270  96.059  1.00 94.95  ? 355 PRO A C   1 
ATOM   2768 O  O   . PRO A 1 355 ? 92.592  78.383  97.271  1.00 94.95  ? 355 PRO A O   1 
ATOM   2769 C  CB  . PRO A 1 355 ? 92.798  80.628  95.187  1.00 94.95  ? 355 PRO A CB  1 
ATOM   2770 C  CG  . PRO A 1 355 ? 93.211  81.172  93.882  1.00 94.95  ? 355 PRO A CG  1 
ATOM   2771 C  CD  . PRO A 1 355 ? 93.455  79.990  93.016  1.00 94.95  ? 355 PRO A CD  1 
ATOM   2772 N  N   . ASN A 1 356 ? 92.338  77.231  95.363  1.00 97.65  ? 356 ASN A N   1 
ATOM   2773 C  CA  . ASN A 1 356 ? 91.654  76.134  96.031  1.00 97.65  ? 356 ASN A CA  1 
ATOM   2774 C  C   . ASN A 1 356 ? 92.611  75.192  96.746  1.00 97.65  ? 356 ASN A C   1 
ATOM   2775 O  O   . ASN A 1 356 ? 92.152  74.267  97.421  1.00 97.65  ? 356 ASN A O   1 
ATOM   2776 C  CB  . ASN A 1 356 ? 90.819  75.351  95.026  1.00 97.65  ? 356 ASN A CB  1 
ATOM   2777 C  CG  . ASN A 1 356 ? 89.706  76.177  94.438  1.00 97.65  ? 356 ASN A CG  1 
ATOM   2778 O  OD1 . ASN A 1 356 ? 88.892  76.744  95.162  1.00 97.65  ? 356 ASN A OD1 1 
ATOM   2779 N  ND2 . ASN A 1 356 ? 89.665  76.258  93.117  1.00 97.65  ? 356 ASN A ND2 1 
ATOM   2780 N  N   . ASP A 1 357 ? 93.922  75.401  96.621  1.00 99.09  ? 357 ASP A N   1 
ATOM   2781 C  CA  . ASP A 1 357 ? 94.876  74.553  97.320  1.00 99.09  ? 357 ASP A CA  1 
ATOM   2782 C  C   . ASP A 1 357 ? 95.033  74.937  98.782  1.00 99.09  ? 357 ASP A C   1 
ATOM   2783 O  O   . ASP A 1 357 ? 95.738  74.241  99.516  1.00 99.09  ? 357 ASP A O   1 
ATOM   2784 C  CB  . ASP A 1 357 ? 96.234  74.600  96.626  1.00 99.09  ? 357 ASP A CB  1 
ATOM   2785 C  CG  . ASP A 1 357 ? 96.158  74.180  95.179  1.00 99.09  ? 357 ASP A CG  1 
ATOM   2786 O  OD1 . ASP A 1 357 ? 95.067  73.771  94.739  1.00 99.09  ? 357 ASP A OD1 1 
ATOM   2787 O  OD2 . ASP A 1 357 ? 97.190  74.245  94.483  1.00 99.09  ? 357 ASP A OD2 1 
ATOM   2788 N  N   . VAL A 1 358 ? 94.392  76.022  99.227  1.00 95.29  ? 358 VAL A N   1 
ATOM   2789 C  CA  . VAL A 1 358 ? 94.445  76.376  100.640 1.00 95.29  ? 358 VAL A CA  1 
ATOM   2790 C  C   . VAL A 1 358 ? 93.512  75.497  101.454 1.00 95.29  ? 358 VAL A C   1 
ATOM   2791 O  O   . VAL A 1 358 ? 93.627  75.438  102.679 1.00 95.29  ? 358 VAL A O   1 
ATOM   2792 C  CB  . VAL A 1 358 ? 94.122  77.867  100.847 1.00 95.29  ? 358 VAL A CB  1 
ATOM   2793 C  CG1 . VAL A 1 358 ? 94.960  78.711  99.935  1.00 95.29  ? 358 VAL A CG1 1 
ATOM   2794 C  CG2 . VAL A 1 358 ? 92.651  78.139  100.621 1.00 95.29  ? 358 VAL A CG2 1 
ATOM   2795 N  N   . PHE A 1 359 ? 92.596  74.782  100.794 1.00 96.33  ? 359 PHE A N   1 
ATOM   2796 C  CA  . PHE A 1 359 ? 91.654  73.923  101.506 1.00 96.33  ? 359 PHE A CA  1 
ATOM   2797 C  C   . PHE A 1 359 ? 92.353  72.726  102.129 1.00 96.33  ? 359 PHE A C   1 
ATOM   2798 O  O   . PHE A 1 359 ? 91.833  72.109  103.064 1.00 96.33  ? 359 PHE A O   1 
ATOM   2799 C  CB  . PHE A 1 359 ? 90.564  73.445  100.554 1.00 96.33  ? 359 PHE A CB  1 
ATOM   2800 C  CG  . PHE A 1 359 ? 89.463  74.427  100.356 1.00 96.33  ? 359 PHE A CG  1 
ATOM   2801 C  CD1 . PHE A 1 359 ? 88.330  74.376  101.140 1.00 96.33  ? 359 PHE A CD1 1 
ATOM   2802 C  CD2 . PHE A 1 359 ? 89.557  75.397  99.381  1.00 96.33  ? 359 PHE A CD2 1 
ATOM   2803 C  CE1 . PHE A 1 359 ? 87.312  75.279  100.957 1.00 96.33  ? 359 PHE A CE1 1 
ATOM   2804 C  CE2 . PHE A 1 359 ? 88.542  76.300  99.194  1.00 96.33  ? 359 PHE A CE2 1 
ATOM   2805 C  CZ  . PHE A 1 359 ? 87.418  76.241  99.984  1.00 96.33  ? 359 PHE A CZ  1 
ATOM   2806 N  N   . ASP A 1 360 ? 93.534  72.381  101.622 1.00 100.41 ? 360 ASP A N   1 
ATOM   2807 C  CA  . ASP A 1 360 ? 94.263  71.244  102.158 1.00 100.41 ? 360 ASP A CA  1 
ATOM   2808 C  C   . ASP A 1 360 ? 94.931  71.595  103.478 1.00 100.41 ? 360 ASP A C   1 
ATOM   2809 O  O   . ASP A 1 360 ? 95.035  70.748  104.372 1.00 100.41 ? 360 ASP A O   1 
ATOM   2810 C  CB  . ASP A 1 360 ? 95.302  70.782  101.142 1.00 100.41 ? 360 ASP A CB  1 
ATOM   2811 C  CG  . ASP A 1 360 ? 94.678  70.365  99.830  1.00 100.41 ? 360 ASP A CG  1 
ATOM   2812 O  OD1 . ASP A 1 360 ? 93.503  69.946  99.837  1.00 100.41 ? 360 ASP A OD1 1 
ATOM   2813 O  OD2 . ASP A 1 360 ? 95.360  70.459  98.788  1.00 100.41 ? 360 ASP A OD2 1 
ATOM   2814 N  N   . VAL A 1 361 ? 95.382  72.843  103.624 1.00 94.92  ? 361 VAL A N   1 
ATOM   2815 C  CA  . VAL A 1 361 ? 96.256  73.218  104.727 1.00 94.92  ? 361 VAL A CA  1 
ATOM   2816 C  C   . VAL A 1 361 ? 95.686  74.322  105.599 1.00 94.92  ? 361 VAL A C   1 
ATOM   2817 O  O   . VAL A 1 361 ? 96.441  74.924  106.366 1.00 94.92  ? 361 VAL A O   1 
ATOM   2818 C  CB  . VAL A 1 361 ? 97.639  73.648  104.204 1.00 94.92  ? 361 VAL A CB  1 
ATOM   2819 C  CG1 . VAL A 1 361 ? 98.363  72.481  103.580 1.00 94.92  ? 361 VAL A CG1 1 
ATOM   2820 C  CG2 . VAL A 1 361 ? 97.494  74.769  103.202 1.00 94.92  ? 361 VAL A CG2 1 
ATOM   2821 N  N   . ILE A 1 362 ? 94.383  74.606  105.526 1.00 93.85  ? 362 ILE A N   1 
ATOM   2822 C  CA  . ILE A 1 362 ? 93.854  75.779  106.216 1.00 93.85  ? 362 ILE A CA  1 
ATOM   2823 C  C   . ILE A 1 362 ? 93.756  75.574  107.722 1.00 93.85  ? 362 ILE A C   1 
ATOM   2824 O  O   . ILE A 1 362 ? 93.648  76.549  108.471 1.00 93.85  ? 362 ILE A O   1 
ATOM   2825 C  CB  . ILE A 1 362 ? 92.486  76.189  105.621 1.00 93.85  ? 362 ILE A CB  1 
ATOM   2826 C  CG1 . ILE A 1 362 ? 92.232  77.687  105.809 1.00 93.85  ? 362 ILE A CG1 1 
ATOM   2827 C  CG2 . ILE A 1 362 ? 91.358  75.366  106.212 1.00 93.85  ? 362 ILE A CG2 1 
ATOM   2828 C  CD1 . ILE A 1 362 ? 93.271  78.571  105.171 1.00 93.85  ? 362 ILE A CD1 1 
ATOM   2829 N  N   . GLU A 1 363 ? 93.832  74.334  108.203 1.00 95.30  ? 363 GLU A N   1 
ATOM   2830 C  CA  . GLU A 1 363 ? 93.719  74.121  109.639 1.00 95.30  ? 363 GLU A CA  1 
ATOM   2831 C  C   . GLU A 1 363 ? 95.041  74.389  110.342 1.00 95.30  ? 363 GLU A C   1 
ATOM   2832 O  O   . GLU A 1 363 ? 95.103  74.403  111.575 1.00 95.30  ? 363 GLU A O   1 
ATOM   2833 C  CB  . GLU A 1 363 ? 93.226  72.705  109.927 1.00 95.30  ? 363 GLU A CB  1 
ATOM   2834 C  CG  . GLU A 1 363 ? 94.257  71.620  109.703 1.00 95.30  ? 363 GLU A CG  1 
ATOM   2835 C  CD  . GLU A 1 363 ? 94.314  71.158  108.263 1.00 95.30  ? 363 GLU A CD  1 
ATOM   2836 O  OE1 . GLU A 1 363 ? 95.294  70.479  107.893 1.00 95.30  ? 363 GLU A OE1 1 
ATOM   2837 O  OE2 . GLU A 1 363 ? 93.377  71.475  107.501 1.00 95.30  ? 363 GLU A OE2 1 
ATOM   2838 N  N   . ASN A 1 364 ? 96.109  74.607  109.578 1.00 89.38  ? 364 ASN A N   1 
ATOM   2839 C  CA  . ASN A 1 364 ? 97.414  74.941  110.127 1.00 89.38  ? 364 ASN A CA  1 
ATOM   2840 C  C   . ASN A 1 364 ? 97.880  76.335  109.742 1.00 89.38  ? 364 ASN A C   1 
ATOM   2841 O  O   . ASN A 1 364 ? 98.964  76.744  110.159 1.00 89.38  ? 364 ASN A O   1 
ATOM   2842 C  CB  . ASN A 1 364 ? 98.452  73.916  109.678 1.00 89.38  ? 364 ASN A CB  1 
ATOM   2843 C  CG  . ASN A 1 364 ? 98.153  72.530  110.184 1.00 89.38  ? 364 ASN A CG  1 
ATOM   2844 O  OD1 . ASN A 1 364 ? 98.203  72.272  111.382 1.00 89.38  ? 364 ASN A OD1 1 
ATOM   2845 N  ND2 . ASN A 1 364 ? 97.840  71.625  109.271 1.00 89.38  ? 364 ASN A ND2 1 
ATOM   2846 N  N   . VAL A 1 365 ? 97.106  77.067  108.951 1.00 84.45  ? 365 VAL A N   1 
ATOM   2847 C  CA  . VAL A 1 365 ? 97.452  78.441  108.612 1.00 84.45  ? 365 VAL A CA  1 
ATOM   2848 C  C   . VAL A 1 365 ? 96.965  79.344  109.731 1.00 84.45  ? 365 VAL A C   1 
ATOM   2849 O  O   . VAL A 1 365 ? 95.766  79.409  110.012 1.00 84.45  ? 365 VAL A O   1 
ATOM   2850 C  CB  . VAL A 1 365 ? 96.845  78.856  107.268 1.00 84.45  ? 365 VAL A CB  1 
ATOM   2851 C  CG1 . VAL A 1 365 ? 97.071  80.326  107.035 1.00 84.45  ? 365 VAL A CG1 1 
ATOM   2852 C  CG2 . VAL A 1 365 ? 97.470  78.069  106.153 1.00 84.45  ? 365 VAL A CG2 1 
ATOM   2853 N  N   . VAL A 1 366 ? 97.894  80.037  110.377 1.00 79.83  ? 366 VAL A N   1 
ATOM   2854 C  CA  . VAL A 1 366 ? 97.559  80.912  111.488 1.00 79.83  ? 366 VAL A CA  1 
ATOM   2855 C  C   . VAL A 1 366 ? 97.651  82.383  111.123 1.00 79.83  ? 366 VAL A C   1 
ATOM   2856 O  O   . VAL A 1 366 ? 97.135  83.221  111.875 1.00 79.83  ? 366 VAL A O   1 
ATOM   2857 C  CB  . VAL A 1 366 ? 98.441  80.616  112.716 1.00 79.83  ? 366 VAL A CB  1 
ATOM   2858 C  CG1 . VAL A 1 366 ? 98.287  79.175  113.136 1.00 79.83  ? 366 VAL A CG1 1 
ATOM   2859 C  CG2 . VAL A 1 366 ? 99.886  80.918  112.408 1.00 79.83  ? 366 VAL A CG2 1 
ATOM   2860 N  N   . PHE A 1 367 ? 98.259  82.724  109.995 1.00 75.15  ? 367 PHE A N   1 
ATOM   2861 C  CA  . PHE A 1 367 ? 98.563  84.103  109.674 1.00 75.15  ? 367 PHE A CA  1 
ATOM   2862 C  C   . PHE A 1 367 ? 98.832  84.190  108.187 1.00 75.15  ? 367 PHE A C   1 
ATOM   2863 O  O   . PHE A 1 367 ? 99.411  83.277  107.600 1.00 75.15  ? 367 PHE A O   1 
ATOM   2864 C  CB  . PHE A 1 367 ? 99.771  84.581  110.470 1.00 75.15  ? 367 PHE A CB  1 
ATOM   2865 C  CG  . PHE A 1 367 ? 99.974  86.047  110.437 1.00 75.15  ? 367 PHE A CG  1 
ATOM   2866 C  CD1 . PHE A 1 367 ? 99.182  86.879  111.190 1.00 75.15  ? 367 PHE A CD1 1 
ATOM   2867 C  CD2 . PHE A 1 367 ? 100.975 86.595  109.670 1.00 75.15  ? 367 PHE A CD2 1 
ATOM   2868 C  CE1 . PHE A 1 367 ? 99.380  88.226  111.167 1.00 75.15  ? 367 PHE A CE1 1 
ATOM   2869 C  CE2 . PHE A 1 367 ? 101.172 87.934  109.645 1.00 75.15  ? 367 PHE A CE2 1 
ATOM   2870 C  CZ  . PHE A 1 367 ? 100.377 88.748  110.396 1.00 75.15  ? 367 PHE A CZ  1 
ATOM   2871 N  N   . ILE A 1 368 ? 98.400  85.284  107.574 1.00 75.90  ? 368 ILE A N   1 
ATOM   2872 C  CA  . ILE A 1 368 ? 98.534  85.466  106.137 1.00 75.90  ? 368 ILE A CA  1 
ATOM   2873 C  C   . ILE A 1 368 ? 99.122  86.840  105.865 1.00 75.90  ? 368 ILE A C   1 
ATOM   2874 O  O   . ILE A 1 368 ? 98.581  87.852  106.317 1.00 75.90  ? 368 ILE A O   1 
ATOM   2875 C  CB  . ILE A 1 368 ? 97.189  85.294  105.410 1.00 75.90  ? 368 ILE A CB  1 
ATOM   2876 C  CG1 . ILE A 1 368 ? 96.802  83.824  105.382 1.00 75.90  ? 368 ILE A CG1 1 
ATOM   2877 C  CG2 . ILE A 1 368 ? 97.282  85.792  104.004 1.00 75.90  ? 368 ILE A CG2 1 
ATOM   2878 C  CD1 . ILE A 1 368 ? 95.524  83.553  104.690 1.00 75.90  ? 368 ILE A CD1 1 
ATOM   2879 N  N   . GLN A 1 369 ? 100.230 86.873  105.137 1.00 79.76  ? 369 GLN A N   1 
ATOM   2880 C  CA  . GLN A 1 369 ? 100.838 88.110  104.677 1.00 79.76  ? 369 GLN A CA  1 
ATOM   2881 C  C   . GLN A 1 369 ? 100.267 88.449  103.311 1.00 79.76  ? 369 GLN A C   1 
ATOM   2882 O  O   . GLN A 1 369 ? 100.556 87.765  102.328 1.00 79.76  ? 369 GLN A O   1 
ATOM   2883 C  CB  . GLN A 1 369 ? 102.353 87.973  104.606 1.00 79.76  ? 369 GLN A CB  1 
ATOM   2884 C  CG  . GLN A 1 369 ? 103.034 88.097  105.934 1.00 79.76  ? 369 GLN A CG  1 
ATOM   2885 C  CD  . GLN A 1 369 ? 104.499 87.776  105.853 1.00 79.76  ? 369 GLN A CD  1 
ATOM   2886 O  OE1 . GLN A 1 369 ? 105.044 87.594  104.770 1.00 79.76  ? 369 GLN A OE1 1 
ATOM   2887 N  NE2 . GLN A 1 369 ? 105.151 87.697  107.002 1.00 79.76  ? 369 GLN A NE2 1 
ATOM   2888 N  N   . ALA A 1 370 ? 99.464  89.502  103.248 1.00 79.09  ? 370 ALA A N   1 
ATOM   2889 C  CA  . ALA A 1 370 ? 98.847  89.930  101.998 1.00 79.09  ? 370 ALA A CA  1 
ATOM   2890 C  C   . ALA A 1 370 ? 99.897  90.648  101.165 1.00 79.09  ? 370 ALA A C   1 
ATOM   2891 O  O   . ALA A 1 370 ? 100.103 91.853  101.303 1.00 79.09  ? 370 ALA A O   1 
ATOM   2892 C  CB  . ALA A 1 370 ? 97.646  90.820  102.276 1.00 79.09  ? 370 ALA A CB  1 
ATOM   2893 N  N   . LYS A 1 371 ? 100.559 89.900  100.292 1.00 81.23  ? 371 LYS A N   1 
ATOM   2894 C  CA  . LYS A 1 371 ? 101.648 90.396  99.467  1.00 81.23  ? 371 LYS A CA  1 
ATOM   2895 C  C   . LYS A 1 371 ? 101.087 90.994  98.188  1.00 81.23  ? 371 LYS A C   1 
ATOM   2896 O  O   . LYS A 1 371 ? 100.228 90.388  97.547  1.00 81.23  ? 371 LYS A O   1 
ATOM   2897 C  CB  . LYS A 1 371 ? 102.611 89.258  99.141  1.00 81.23  ? 371 LYS A CB  1 
ATOM   2898 C  CG  . LYS A 1 371 ? 103.717 89.600  98.187  1.00 81.23  ? 371 LYS A CG  1 
ATOM   2899 C  CD  . LYS A 1 371 ? 104.829 90.320  98.893  1.00 81.23  ? 371 LYS A CD  1 
ATOM   2900 C  CE  . LYS A 1 371 ? 105.536 89.408  99.860  1.00 81.23  ? 371 LYS A CE  1 
ATOM   2901 N  NZ  . LYS A 1 371 ? 106.159 88.256  99.172  1.00 81.23  ? 371 LYS A NZ  1 
ATOM   2902 N  N   . PHE A 1 372 ? 101.568 92.177  97.821  1.00 76.48  ? 372 PHE A N   1 
ATOM   2903 C  CA  . PHE A 1 372 ? 101.120 92.833  96.605  1.00 76.48  ? 372 PHE A CA  1 
ATOM   2904 C  C   . PHE A 1 372 ? 102.208 93.776  96.125  1.00 76.48  ? 372 PHE A C   1 
ATOM   2905 O  O   . PHE A 1 372 ? 103.122 94.127  96.870  1.00 76.48  ? 372 PHE A O   1 
ATOM   2906 C  CB  . PHE A 1 372 ? 99.802  93.582  96.814  1.00 76.48  ? 372 PHE A CB  1 
ATOM   2907 C  CG  . PHE A 1 372 ? 99.944  94.888  97.532  1.00 76.48  ? 372 PHE A CG  1 
ATOM   2908 C  CD1 . PHE A 1 372 ? 100.215 94.927  98.885  1.00 76.48  ? 372 PHE A CD1 1 
ATOM   2909 C  CD2 . PHE A 1 372 ? 99.774  96.078  96.859  1.00 76.48  ? 372 PHE A CD2 1 
ATOM   2910 C  CE1 . PHE A 1 372 ? 100.332 96.120  99.541  1.00 76.48  ? 372 PHE A CE1 1 
ATOM   2911 C  CE2 . PHE A 1 372 ? 99.894  97.270  97.515  1.00 76.48  ? 372 PHE A CE2 1 
ATOM   2912 C  CZ  . PHE A 1 372 ? 100.172 97.289  98.857  1.00 76.48  ? 372 PHE A CZ  1 
ATOM   2913 N  N   . HIS A 1 373 ? 102.100 94.183  94.866  1.00 80.37  ? 373 HIS A N   1 
ATOM   2914 C  CA  . HIS A 1 373 ? 103.110 95.019  94.240  1.00 80.37  ? 373 HIS A CA  1 
ATOM   2915 C  C   . HIS A 1 373 ? 102.576 96.307  93.649  1.00 80.37  ? 373 HIS A C   1 
ATOM   2916 O  O   . HIS A 1 373 ? 103.275 97.316  93.701  1.00 80.37  ? 373 HIS A O   1 
ATOM   2917 C  CB  . HIS A 1 373 ? 103.834 94.247  93.132  1.00 80.37  ? 373 HIS A CB  1 
ATOM   2918 C  CG  . HIS A 1 373 ? 104.489 92.993  93.606  1.00 80.37  ? 373 HIS A CG  1 
ATOM   2919 N  ND1 . HIS A 1 373 ? 103.791 91.829  93.832  1.00 80.37  ? 373 HIS A ND1 1 
ATOM   2920 C  CD2 . HIS A 1 373 ? 105.778 92.722  93.906  1.00 80.37  ? 373 HIS A CD2 1 
ATOM   2921 C  CE1 . HIS A 1 373 ? 104.622 90.895  94.251  1.00 80.37  ? 373 HIS A CE1 1 
ATOM   2922 N  NE2 . HIS A 1 373 ? 105.834 91.412  94.307  1.00 80.37  ? 373 HIS A NE2 1 
ATOM   2923 N  N   . ASP A 1 374 ? 101.370 96.310  93.090  1.00 82.25  ? 374 ASP A N   1 
ATOM   2924 C  CA  . ASP A 1 374 ? 100.878 97.496  92.407  1.00 82.25  ? 374 ASP A CA  1 
ATOM   2925 C  C   . ASP A 1 374 ? 99.362  97.480  92.366  1.00 82.25  ? 374 ASP A C   1 
ATOM   2926 O  O   . ASP A 1 374 ? 98.763  96.497  91.938  1.00 82.25  ? 374 ASP A O   1 
ATOM   2927 C  CB  . ASP A 1 374 ? 101.432 97.577  90.988  1.00 82.25  ? 374 ASP A CB  1 
ATOM   2928 C  CG  . ASP A 1 374 ? 101.385 98.972  90.432  1.00 82.25  ? 374 ASP A CG  1 
ATOM   2929 O  OD1 . ASP A 1 374 ? 101.363 99.928  91.230  1.00 82.25  ? 374 ASP A OD1 1 
ATOM   2930 O  OD2 . ASP A 1 374 ? 101.366 99.116  89.195  1.00 82.25  ? 374 ASP A OD2 1 
ATOM   2931 N  N   . ILE A 1 375 ? 98.754  98.571  92.819  1.00 79.98  ? 375 ILE A N   1 
ATOM   2932 C  CA  . ILE A 1 375 ? 97.320  98.807  92.697  1.00 79.98  ? 375 ILE A CA  1 
ATOM   2933 C  C   . ILE A 1 375 ? 97.139  100.225 92.180  1.00 79.98  ? 375 ILE A C   1 
ATOM   2934 O  O   . ILE A 1 375 ? 97.673  101.171 92.766  1.00 79.98  ? 375 ILE A O   1 
ATOM   2935 C  CB  . ILE A 1 375 ? 96.585  98.614  94.038  1.00 79.98  ? 375 ILE A CB  1 
ATOM   2936 C  CG1 . ILE A 1 375 ? 96.664  97.161  94.492  1.00 79.98  ? 375 ILE A CG1 1 
ATOM   2937 C  CG2 . ILE A 1 375 ? 95.138  99.006  93.915  1.00 79.98  ? 375 ILE A CG2 1 
ATOM   2938 C  CD1 . ILE A 1 375 ? 96.230  96.938  95.886  1.00 79.98  ? 375 ILE A CD1 1 
ATOM   2939 N  N   . ASP A 1 376 ? 96.407  100.378 91.081  1.00 86.01  ? 376 ASP A N   1 
ATOM   2940 C  CA  . ASP A 1 376 ? 96.263  101.679 90.447  1.00 86.01  ? 376 ASP A CA  1 
ATOM   2941 C  C   . ASP A 1 376 ? 95.044  102.415 91.006  1.00 86.01  ? 376 ASP A C   1 
ATOM   2942 O  O   . ASP A 1 376 ? 94.451  102.014 92.009  1.00 86.01  ? 376 ASP A O   1 
ATOM   2943 C  CB  . ASP A 1 376 ? 96.187  101.525 88.933  1.00 86.01  ? 376 ASP A CB  1 
ATOM   2944 C  CG  . ASP A 1 376 ? 94.927  100.840 88.483  1.00 86.01  ? 376 ASP A CG  1 
ATOM   2945 O  OD1 . ASP A 1 376 ? 94.414  99.999  89.237  1.00 86.01  ? 376 ASP A OD1 1 
ATOM   2946 O  OD2 . ASP A 1 376 ? 94.446  101.136 87.374  1.00 86.01  ? 376 ASP A OD2 1 
ATOM   2947 N  N   . GLU A 1 377 ? 94.648  103.501 90.342  1.00 85.54  ? 377 GLU A N   1 
ATOM   2948 C  CA  . GLU A 1 377 ? 93.610  104.377 90.870  1.00 85.54  ? 377 GLU A CA  1 
ATOM   2949 C  C   . GLU A 1 377 ? 92.207  103.824 90.694  1.00 85.54  ? 377 GLU A C   1 
ATOM   2950 O  O   . GLU A 1 377 ? 91.265  104.386 91.257  1.00 85.54  ? 377 GLU A O   1 
ATOM   2951 C  CB  . GLU A 1 377 ? 93.700  105.742 90.207  1.00 85.54  ? 377 GLU A CB  1 
ATOM   2952 C  CG  . GLU A 1 377 ? 94.899  106.528 90.644  1.00 85.54  ? 377 GLU A CG  1 
ATOM   2953 C  CD  . GLU A 1 377 ? 96.067  106.358 89.711  1.00 85.54  ? 377 GLU A CD  1 
ATOM   2954 O  OE1 . GLU A 1 377 ? 95.925  105.625 88.712  1.00 85.54  ? 377 GLU A OE1 1 
ATOM   2955 O  OE2 . GLU A 1 377 ? 97.128  106.961 89.976  1.00 85.54  ? 377 GLU A OE2 1 
ATOM   2956 N  N   . GLU A 1 378 ? 92.035  102.755 89.926  1.00 88.61  ? 378 GLU A N   1 
ATOM   2957 C  CA  . GLU A 1 378 ? 90.742  102.104 89.798  1.00 88.61  ? 378 GLU A CA  1 
ATOM   2958 C  C   . GLU A 1 378 ? 90.587  100.941 90.757  1.00 88.61  ? 378 GLU A C   1 
ATOM   2959 O  O   . GLU A 1 378 ? 89.636  100.165 90.614  1.00 88.61  ? 378 GLU A O   1 
ATOM   2960 C  CB  . GLU A 1 378 ? 90.529  101.620 88.367  1.00 88.61  ? 378 GLU A CB  1 
ATOM   2961 C  CG  . GLU A 1 378 ? 89.804  102.609 87.496  1.00 88.61  ? 378 GLU A CG  1 
ATOM   2962 C  CD  . GLU A 1 378 ? 90.620  103.852 87.244  1.00 88.61  ? 378 GLU A CD  1 
ATOM   2963 O  OE1 . GLU A 1 378 ? 91.850  103.728 87.075  1.00 88.61  ? 378 GLU A OE1 1 
ATOM   2964 O  OE2 . GLU A 1 378 ? 90.035  104.953 87.220  1.00 88.61  ? 378 GLU A OE2 1 
ATOM   2965 N  N   . LEU A 1 379 ? 91.492  100.827 91.735  1.00 83.64  ? 379 LEU A N   1 
ATOM   2966 C  CA  . LEU A 1 379 ? 91.590  99.697  92.660  1.00 83.64  ? 379 LEU A CA  1 
ATOM   2967 C  C   . LEU A 1 379 ? 91.681  98.373  91.913  1.00 83.64  ? 379 LEU A C   1 
ATOM   2968 O  O   . LEU A 1 379 ? 90.950  97.427  92.197  1.00 83.64  ? 379 LEU A O   1 
ATOM   2969 C  CB  . LEU A 1 379 ? 90.438  99.681  93.666  1.00 83.64  ? 379 LEU A CB  1 
ATOM   2970 C  CG  . LEU A 1 379 ? 90.427  100.763 94.741  1.00 83.64  ? 379 LEU A CG  1 
ATOM   2971 C  CD1 . LEU A 1 379 ? 89.394  100.426 95.782  1.00 83.64  ? 379 LEU A CD1 1 
ATOM   2972 C  CD2 . LEU A 1 379 ? 91.785  100.906 95.372  1.00 83.64  ? 379 LEU A CD2 1 
ATOM   2973 N  N   . ASP A 1 380 ? 92.575  98.310  90.937  1.00 87.93  ? 380 ASP A N   1 
ATOM   2974 C  CA  . ASP A 1 380 ? 92.838  97.093  90.187  1.00 87.93  ? 380 ASP A CA  1 
ATOM   2975 C  C   . ASP A 1 380 ? 94.252  96.631  90.502  1.00 87.93  ? 380 ASP A C   1 
ATOM   2976 O  O   . ASP A 1 380 ? 95.216  97.351  90.232  1.00 87.93  ? 380 ASP A O   1 
ATOM   2977 C  CB  . ASP A 1 380 ? 92.660  97.324  88.689  1.00 87.93  ? 380 ASP A CB  1 
ATOM   2978 C  CG  . ASP A 1 380 ? 93.026  96.114  87.864  1.00 87.93  ? 380 ASP A CG  1 
ATOM   2979 O  OD1 . ASP A 1 380 ? 93.571  96.297  86.759  1.00 87.93  ? 380 ASP A OD1 1 
ATOM   2980 O  OD2 . ASP A 1 380 ? 92.762  94.978  88.309  1.00 87.93  ? 380 ASP A OD2 1 
ATOM   2981 N  N   . ASP A 1 381 ? 94.370  95.445  91.084  1.00 87.64  ? 381 ASP A N   1 
ATOM   2982 C  CA  . ASP A 1 381 ? 95.675  94.867  91.352  1.00 87.64  ? 381 ASP A CA  1 
ATOM   2983 C  C   . ASP A 1 381 ? 96.278  94.357  90.054  1.00 87.64  ? 381 ASP A C   1 
ATOM   2984 O  O   . ASP A 1 381 ? 95.573  93.812  89.201  1.00 87.64  ? 381 ASP A O   1 
ATOM   2985 C  CB  . ASP A 1 381 ? 95.564  93.734  92.366  1.00 87.64  ? 381 ASP A CB  1 
ATOM   2986 C  CG  . ASP A 1 381 ? 96.883  93.426  93.048  1.00 87.64  ? 381 ASP A CG  1 
ATOM   2987 O  OD1 . ASP A 1 381 ? 97.852  93.057  92.358  1.00 87.64  ? 381 ASP A OD1 1 
ATOM   2988 O  OD2 . ASP A 1 381 ? 96.954  93.547  94.285  1.00 87.64  ? 381 ASP A OD2 1 
ATOM   2989 N  N   . LYS A 1 382 ? 97.582  94.531  89.909  1.00 88.60  ? 382 LYS A N   1 
ATOM   2990 C  CA  . LYS A 1 382 ? 98.270  94.163  88.687  1.00 88.60  ? 382 LYS A CA  1 
ATOM   2991 C  C   . LYS A 1 382 ? 98.940  92.802  88.756  1.00 88.60  ? 382 LYS A C   1 
ATOM   2992 O  O   . LYS A 1 382 ? 99.416  92.316  87.727  1.00 88.60  ? 382 LYS A O   1 
ATOM   2993 C  CB  . LYS A 1 382 ? 99.315  95.222  88.343  1.00 88.60  ? 382 LYS A CB  1 
ATOM   2994 C  CG  . LYS A 1 382 ? 98.745  96.605  88.174  1.00 88.60  ? 382 LYS A CG  1 
ATOM   2995 C  CD  . LYS A 1 382 ? 97.678  96.612  87.107  1.00 88.60  ? 382 LYS A CD  1 
ATOM   2996 C  CE  . LYS A 1 382 ? 97.105  97.992  86.911  1.00 88.60  ? 382 LYS A CE  1 
ATOM   2997 N  NZ  . LYS A 1 382 ? 95.885  97.938  86.070  1.00 88.60  ? 382 LYS A NZ  1 
ATOM   2998 N  N   . GLN A 1 383 ? 98.999  92.177  89.925  1.00 90.27  ? 383 GLN A N   1 
ATOM   2999 C  CA  . GLN A 1 383 ? 99.705  90.908  90.019  1.00 90.27  ? 383 GLN A CA  1 
ATOM   3000 C  C   . GLN A 1 383 ? 98.906  89.813  90.707  1.00 90.27  ? 383 GLN A C   1 
ATOM   3001 O  O   . GLN A 1 383 ? 99.077  88.643  90.373  1.00 90.27  ? 383 GLN A O   1 
ATOM   3002 C  CB  . GLN A 1 383 ? 101.032 91.102  90.746  1.00 90.27  ? 383 GLN A CB  1 
ATOM   3003 C  CG  . GLN A 1 383 ? 102.183 91.466  89.843  1.00 90.27  ? 383 GLN A CG  1 
ATOM   3004 C  CD  . GLN A 1 383 ? 102.258 92.945  89.573  1.00 90.27  ? 383 GLN A CD  1 
ATOM   3005 O  OE1 . GLN A 1 383 ? 101.943 93.755  90.434  1.00 90.27  ? 383 GLN A OE1 1 
ATOM   3006 N  NE2 . GLN A 1 383 ? 102.678 93.308  88.374  1.00 90.27  ? 383 GLN A NE2 1 
ATOM   3007 N  N   . ILE A 1 384 ? 98.045  90.153  91.653  1.00 85.76  ? 384 ILE A N   1 
ATOM   3008 C  CA  . ILE A 1 384 ? 97.357  89.168  92.485  1.00 85.76  ? 384 ILE A CA  1 
ATOM   3009 C  C   . ILE A 1 384 ? 95.876  89.166  92.121  1.00 85.76  ? 384 ILE A C   1 
ATOM   3010 O  O   . ILE A 1 384 ? 95.259  90.234  92.099  1.00 85.76  ? 384 ILE A O   1 
ATOM   3011 C  CB  . ILE A 1 384 ? 97.540  89.456  93.985  1.00 85.76  ? 384 ILE A CB  1 
ATOM   3012 C  CG1 . ILE A 1 384 ? 98.963  89.929  94.280  1.00 85.76  ? 384 ILE A CG1 1 
ATOM   3013 C  CG2 . ILE A 1 384 ? 97.185  88.231  94.806  1.00 85.76  ? 384 ILE A CG2 1 
ATOM   3014 C  CD1 . ILE A 1 384 ? 100.011 88.867  94.159  1.00 85.76  ? 384 ILE A CD1 1 
ATOM   3015 N  N   . PRO A 1 385 ? 95.286  88.016  91.836  1.00 86.73  ? 385 PRO A N   1 
ATOM   3016 C  CA  . PRO A 1 385 ? 93.833  87.947  91.642  1.00 86.73  ? 385 PRO A CA  1 
ATOM   3017 C  C   . PRO A 1 385 ? 93.077  87.887  92.958  1.00 86.73  ? 385 PRO A C   1 
ATOM   3018 O  O   . PRO A 1 385 ? 92.774  86.800  93.450  1.00 86.73  ? 385 PRO A O   1 
ATOM   3019 C  CB  . PRO A 1 385 ? 93.652  86.662  90.831  1.00 86.73  ? 385 PRO A CB  1 
ATOM   3020 C  CG  . PRO A 1 385 ? 94.835  85.839  91.155  1.00 86.73  ? 385 PRO A CG  1 
ATOM   3021 C  CD  . PRO A 1 385 ? 95.957  86.759  91.482  1.00 86.73  ? 385 PRO A CD  1 
ATOM   3022 N  N   . TRP A 1 386 ? 92.767  89.050  93.533  1.00 82.36  ? 386 TRP A N   1 
ATOM   3023 C  CA  . TRP A 1 386 ? 92.332  89.105  94.924  1.00 82.36  ? 386 TRP A CA  1 
ATOM   3024 C  C   . TRP A 1 386 ? 90.948  88.514  95.132  1.00 82.36  ? 386 TRP A C   1 
ATOM   3025 O  O   . TRP A 1 386 ? 90.643  88.024  96.221  1.00 82.36  ? 386 TRP A O   1 
ATOM   3026 C  CB  . TRP A 1 386 ? 92.359  90.542  95.424  1.00 82.36  ? 386 TRP A CB  1 
ATOM   3027 C  CG  . TRP A 1 386 ? 93.694  90.954  95.871  1.00 82.36  ? 386 TRP A CG  1 
ATOM   3028 C  CD1 . TRP A 1 386 ? 94.494  91.874  95.287  1.00 82.36  ? 386 TRP A CD1 1 
ATOM   3029 C  CD2 . TRP A 1 386 ? 94.412  90.451  96.997  1.00 82.36  ? 386 TRP A CD2 1 
ATOM   3030 N  NE1 . TRP A 1 386 ? 95.668  91.987  95.977  1.00 82.36  ? 386 TRP A NE1 1 
ATOM   3031 C  CE2 . TRP A 1 386 ? 95.642  91.120  97.034  1.00 82.36  ? 386 TRP A CE2 1 
ATOM   3032 C  CE3 . TRP A 1 386 ? 94.132  89.502  97.982  1.00 82.36  ? 386 TRP A CE3 1 
ATOM   3033 C  CZ2 . TRP A 1 386 ? 96.589  90.873  98.010  1.00 82.36  ? 386 TRP A CZ2 1 
ATOM   3034 C  CZ3 . TRP A 1 386 ? 95.069  89.259  98.946  1.00 82.36  ? 386 TRP A CZ3 1 
ATOM   3035 C  CH2 . TRP A 1 386 ? 96.284  89.941  98.957  1.00 82.36  ? 386 TRP A CH2 1 
ATOM   3036 N  N   . GLU A 1 387 ? 90.097  88.542  94.116  1.00 86.02  ? 387 GLU A N   1 
ATOM   3037 C  CA  . GLU A 1 387 ? 88.728  88.080  94.331  1.00 86.02  ? 387 GLU A CA  1 
ATOM   3038 C  C   . GLU A 1 387 ? 88.595  86.561  94.433  1.00 86.02  ? 387 GLU A C   1 
ATOM   3039 O  O   . GLU A 1 387 ? 87.900  86.102  95.354  1.00 86.02  ? 387 GLU A O   1 
ATOM   3040 C  CB  . GLU A 1 387 ? 87.801  88.677  93.269  1.00 86.02  ? 387 GLU A CB  1 
ATOM   3041 C  CG  . GLU A 1 387 ? 86.351  88.332  93.497  1.00 86.02  ? 387 GLU A CG  1 
ATOM   3042 C  CD  . GLU A 1 387 ? 85.449  88.834  92.398  1.00 86.02  ? 387 GLU A CD  1 
ATOM   3043 O  OE1 . GLU A 1 387 ? 84.712  88.014  91.815  1.00 86.02  ? 387 GLU A OE1 1 
ATOM   3044 O  OE2 . GLU A 1 387 ? 85.473  90.050  92.119  1.00 86.02  ? 387 GLU A OE2 1 
ATOM   3045 N  N   . PRO A 1 388 ? 89.214  85.722  93.577  1.00 84.80  ? 388 PRO A N   1 
ATOM   3046 C  CA  . PRO A 1 388 ? 89.127  84.278  93.854  1.00 84.80  ? 388 PRO A CA  1 
ATOM   3047 C  C   . PRO A 1 388 ? 89.970  83.830  95.031  1.00 84.80  ? 388 PRO A C   1 
ATOM   3048 O  O   . PRO A 1 388 ? 89.696  82.774  95.610  1.00 84.80  ? 388 PRO A O   1 
ATOM   3049 C  CB  . PRO A 1 388 ? 89.605  83.647  92.544  1.00 84.80  ? 388 PRO A CB  1 
ATOM   3050 C  CG  . PRO A 1 388 ? 90.485  84.633  91.980  1.00 84.80  ? 388 PRO A CG  1 
ATOM   3051 C  CD  . PRO A 1 388 ? 89.818  85.925  92.244  1.00 84.80  ? 388 PRO A CD  1 
ATOM   3052 N  N   . VAL A 1 389 ? 90.993  84.599  95.400  1.00 83.77  ? 389 VAL A N   1 
ATOM   3053 C  CA  . VAL A 1 389 ? 91.818  84.251  96.553  1.00 83.77  ? 389 VAL A CA  1 
ATOM   3054 C  C   . VAL A 1 389 ? 91.037  84.458  97.842  1.00 83.77  ? 389 VAL A C   1 
ATOM   3055 O  O   . VAL A 1 389 ? 90.992  83.581  98.711  1.00 83.77  ? 389 VAL A O   1 
ATOM   3056 C  CB  . VAL A 1 389 ? 93.120  85.071  96.539  1.00 83.77  ? 389 VAL A CB  1 
ATOM   3057 C  CG1 . VAL A 1 389 ? 93.797  85.045  97.891  1.00 83.77  ? 389 VAL A CG1 1 
ATOM   3058 C  CG2 . VAL A 1 389 ? 94.056  84.541  95.484  1.00 83.77  ? 389 VAL A CG2 1 
ATOM   3059 N  N   . LEU A 1 390 ? 90.390  85.618  97.972  1.00 82.12  ? 390 LEU A N   1 
ATOM   3060 C  CA  . LEU A 1 390 ? 89.622  85.917  99.173  1.00 82.12  ? 390 LEU A CA  1 
ATOM   3061 C  C   . LEU A 1 390 ? 88.348  85.095  99.247  1.00 82.12  ? 390 LEU A C   1 
ATOM   3062 O  O   . LEU A 1 390 ? 87.819  84.871  100.338 1.00 82.12  ? 390 LEU A O   1 
ATOM   3063 C  CB  . LEU A 1 390 ? 89.286  87.400  99.223  1.00 82.12  ? 390 LEU A CB  1 
ATOM   3064 C  CG  . LEU A 1 390 ? 90.467  88.304  99.524  1.00 82.12  ? 390 LEU A CG  1 
ATOM   3065 C  CD1 . LEU A 1 390 ? 90.081  89.723  99.250  1.00 82.12  ? 390 LEU A CD1 1 
ATOM   3066 C  CD2 . LEU A 1 390 ? 90.895  88.134  100.953 1.00 82.12  ? 390 LEU A CD2 1 
ATOM   3067 N  N   . LYS A 1 391 ? 87.832  84.649  98.104  1.00 84.24  ? 391 LYS A N   1 
ATOM   3068 C  CA  . LYS A 1 391 ? 86.665  83.780  98.123  1.00 84.24  ? 391 LYS A CA  1 
ATOM   3069 C  C   . LYS A 1 391 ? 87.020  82.402  98.656  1.00 84.24  ? 391 LYS A C   1 
ATOM   3070 O  O   . LYS A 1 391 ? 86.233  81.786  99.382  1.00 84.24  ? 391 LYS A O   1 
ATOM   3071 C  CB  . LYS A 1 391 ? 86.073  83.672  96.725  1.00 84.24  ? 391 LYS A CB  1 
ATOM   3072 C  CG  . LYS A 1 391 ? 84.728  83.010  96.694  1.00 84.24  ? 391 LYS A CG  1 
ATOM   3073 C  CD  . LYS A 1 391 ? 84.440  82.427  95.335  1.00 84.24  ? 391 LYS A CD  1 
ATOM   3074 C  CE  . LYS A 1 391 ? 82.963  82.151  95.181  1.00 84.24  ? 391 LYS A CE  1 
ATOM   3075 N  NZ  . LYS A 1 391 ? 82.345  81.757  96.475  1.00 84.24  ? 391 LYS A NZ  1 
ATOM   3076 N  N   . ALA A 1 392 ? 88.212  81.909  98.320  1.00 85.46  ? 392 ALA A N   1 
ATOM   3077 C  CA  . ALA A 1 392 ? 88.626  80.594  98.789  1.00 85.46  ? 392 ALA A CA  1 
ATOM   3078 C  C   . ALA A 1 392 ? 89.017  80.628  100.256 1.00 85.46  ? 392 ALA A C   1 
ATOM   3079 O  O   . ALA A 1 392 ? 88.840  79.639  100.970 1.00 85.46  ? 392 ALA A O   1 
ATOM   3080 C  CB  . ALA A 1 392 ? 89.782  80.076  97.945  1.00 85.46  ? 392 ALA A CB  1 
ATOM   3081 N  N   . LEU A 1 393 ? 89.566  81.751  100.720 1.00 83.50  ? 393 LEU A N   1 
ATOM   3082 C  CA  . LEU A 1 393 ? 89.904  81.877  102.134 1.00 83.50  ? 393 LEU A CA  1 
ATOM   3083 C  C   . LEU A 1 393 ? 88.654  81.938  102.994 1.00 83.50  ? 393 LEU A C   1 
ATOM   3084 O  O   . LEU A 1 393 ? 88.613  81.360  104.085 1.00 83.50  ? 393 LEU A O   1 
ATOM   3085 C  CB  . LEU A 1 393 ? 90.750  83.123  102.363 1.00 83.50  ? 393 LEU A CB  1 
ATOM   3086 C  CG  . LEU A 1 393 ? 92.194  83.061  101.894 1.00 83.50  ? 393 LEU A CG  1 
ATOM   3087 C  CD1 . LEU A 1 393 ? 92.879  84.378  102.169 1.00 83.50  ? 393 LEU A CD1 1 
ATOM   3088 C  CD2 . LEU A 1 393 ? 92.903  81.928  102.583 1.00 83.50  ? 393 LEU A CD2 1 
ATOM   3089 N  N   . LYS A 1 394 ? 87.627  82.639  102.516 1.00 85.49  ? 394 LYS A N   1 
ATOM   3090 C  CA  . LYS A 1 394 ? 86.377  82.759  103.249 1.00 85.49  ? 394 LYS A CA  1 
ATOM   3091 C  C   . LYS A 1 394 ? 85.637  81.435  103.329 1.00 85.49  ? 394 LYS A C   1 
ATOM   3092 O  O   . LYS A 1 394 ? 85.095  81.096  104.385 1.00 85.49  ? 394 LYS A O   1 
ATOM   3093 C  CB  . LYS A 1 394 ? 85.501  83.816  102.586 1.00 85.49  ? 394 LYS A CB  1 
ATOM   3094 C  CG  . LYS A 1 394 ? 84.138  84.000  103.205 1.00 85.49  ? 394 LYS A CG  1 
ATOM   3095 C  CD  . LYS A 1 394 ? 83.278  84.866  102.317 1.00 85.49  ? 394 LYS A CD  1 
ATOM   3096 C  CE  . LYS A 1 394 ? 81.843  84.872  102.775 1.00 85.49  ? 394 LYS A CE  1 
ATOM   3097 N  NZ  . LYS A 1 394 ? 81.712  85.548  104.085 1.00 85.49  ? 394 LYS A NZ  1 
ATOM   3098 N  N   . ASP A 1 395 ? 85.620  80.668  102.241 1.00 88.90  ? 395 ASP A N   1 
ATOM   3099 C  CA  . ASP A 1 395 ? 84.912  79.394  102.251 1.00 88.90  ? 395 ASP A CA  1 
ATOM   3100 C  C   . ASP A 1 395 ? 85.683  78.315  102.996 1.00 88.90  ? 395 ASP A C   1 
ATOM   3101 O  O   . ASP A 1 395 ? 85.079  77.360  103.493 1.00 88.90  ? 395 ASP A O   1 
ATOM   3102 C  CB  . ASP A 1 395 ? 84.625  78.935  100.825 1.00 88.90  ? 395 ASP A CB  1 
ATOM   3103 C  CG  . ASP A 1 395 ? 83.583  79.784  100.142 1.00 88.90  ? 395 ASP A CG  1 
ATOM   3104 O  OD1 . ASP A 1 395 ? 82.727  80.359  100.844 1.00 88.90  ? 395 ASP A OD1 1 
ATOM   3105 O  OD2 . ASP A 1 395 ? 83.612  79.872  98.899  1.00 88.90  ? 395 ASP A OD2 1 
ATOM   3106 N  N   . ALA A 1 396 ? 87.003  78.441  103.090 1.00 87.53  ? 396 ALA A N   1 
ATOM   3107 C  CA  . ALA A 1 396 ? 87.769  77.494  103.885 1.00 87.53  ? 396 ALA A CA  1 
ATOM   3108 C  C   . ALA A 1 396 ? 87.662  77.771  105.373 1.00 87.53  ? 396 ALA A C   1 
ATOM   3109 O  O   . ALA A 1 396 ? 88.114  76.949  106.173 1.00 87.53  ? 396 ALA A O   1 
ATOM   3110 C  CB  . ALA A 1 396 ? 89.236  77.507  103.467 1.00 87.53  ? 396 ALA A CB  1 
ATOM   3111 N  N   . GLY A 1 397 ? 87.086  78.900  105.760 1.00 83.56  ? 397 GLY A N   1 
ATOM   3112 C  CA  . GLY A 1 397 ? 86.866  79.210  107.149 1.00 83.56  ? 397 GLY A CA  1 
ATOM   3113 C  C   . GLY A 1 397 ? 87.939  80.039  107.804 1.00 83.56  ? 397 GLY A C   1 
ATOM   3114 O  O   . GLY A 1 397 ? 88.030  80.033  109.035 1.00 83.56  ? 397 GLY A O   1 
ATOM   3115 N  N   . TYR A 1 398 ? 88.761  80.740  107.032 1.00 79.02  ? 398 TYR A N   1 
ATOM   3116 C  CA  . TYR A 1 398 ? 89.799  81.567  107.624 1.00 79.02  ? 398 TYR A CA  1 
ATOM   3117 C  C   . TYR A 1 398 ? 89.186  82.822  108.217 1.00 79.02  ? 398 TYR A C   1 
ATOM   3118 O  O   . TYR A 1 398 ? 88.402  83.511  107.563 1.00 79.02  ? 398 TYR A O   1 
ATOM   3119 C  CB  . TYR A 1 398 ? 90.846  81.933  106.582 1.00 79.02  ? 398 TYR A CB  1 
ATOM   3120 C  CG  . TYR A 1 398 ? 92.020  82.677  107.156 1.00 79.02  ? 398 TYR A CG  1 
ATOM   3121 C  CD1 . TYR A 1 398 ? 92.940  82.035  107.966 1.00 79.02  ? 398 TYR A CD1 1 
ATOM   3122 C  CD2 . TYR A 1 398 ? 92.204  84.020  106.896 1.00 79.02  ? 398 TYR A CD2 1 
ATOM   3123 C  CE1 . TYR A 1 398 ? 94.009  82.709  108.495 1.00 79.02  ? 398 TYR A CE1 1 
ATOM   3124 C  CE2 . TYR A 1 398 ? 93.270  84.700  107.420 1.00 79.02  ? 398 TYR A CE2 1 
ATOM   3125 C  CZ  . TYR A 1 398 ? 94.167  84.040  108.217 1.00 79.02  ? 398 TYR A CZ  1 
ATOM   3126 O  OH  . TYR A 1 398 ? 95.231  84.720  108.739 1.00 79.02  ? 398 TYR A OH  1 
ATOM   3127 N  N   . THR A 1 399 ? 89.525  83.105  109.473 1.00 79.72  ? 399 THR A N   1 
ATOM   3128 C  CA  . THR A 1 399 ? 89.011  84.284  110.159 1.00 79.72  ? 399 THR A CA  1 
ATOM   3129 C  C   . THR A 1 399 ? 90.121  85.077  110.835 1.00 79.72  ? 399 THR A C   1 
ATOM   3130 O  O   . THR A 1 399 ? 89.839  85.873  111.732 1.00 79.72  ? 399 THR A O   1 
ATOM   3131 C  CB  . THR A 1 399 ? 87.963  83.902  111.203 1.00 79.72  ? 399 THR A CB  1 
ATOM   3132 O  OG1 . THR A 1 399 ? 88.448  82.809  111.986 1.00 79.72  ? 399 THR A OG1 1 
ATOM   3133 C  CG2 . THR A 1 399 ? 86.661  83.503  110.544 1.00 79.72  ? 399 THR A CG2 1 
ATOM   3134 N  N   . GLY A 1 400 ? 91.366  84.878  110.434 1.00 76.61  ? 400 GLY A N   1 
ATOM   3135 C  CA  . GLY A 1 400 ? 92.498  85.515  111.067 1.00 76.61  ? 400 GLY A CA  1 
ATOM   3136 C  C   . GLY A 1 400 ? 92.874  86.829  110.424 1.00 76.61  ? 400 GLY A C   1 
ATOM   3137 O  O   . GLY A 1 400 ? 92.038  87.557  109.890 1.00 76.61  ? 400 GLY A O   1 
ATOM   3138 N  N   . TYR A 1 401 ? 94.163  87.126  110.473 1.00 73.50  ? 401 TYR A N   1 
ATOM   3139 C  CA  . TYR A 1 401 ? 94.666  88.403  110.005 1.00 73.50  ? 401 TYR A CA  1 
ATOM   3140 C  C   . TYR A 1 401 ? 95.104  88.328  108.554 1.00 73.50  ? 401 TYR A C   1 
ATOM   3141 O  O   . TYR A 1 401 ? 95.513  87.279  108.059 1.00 73.50  ? 401 TYR A O   1 
ATOM   3142 C  CB  . TYR A 1 401 ? 95.846  88.851  110.857 1.00 73.50  ? 401 TYR A CB  1 
ATOM   3143 C  CG  . TYR A 1 401 ? 95.452  89.690  112.031 1.00 73.50  ? 401 TYR A CG  1 
ATOM   3144 C  CD1 . TYR A 1 401 ? 95.281  91.052  111.898 1.00 73.50  ? 401 TYR A CD1 1 
ATOM   3145 C  CD2 . TYR A 1 401 ? 95.247  89.119  113.272 1.00 73.50  ? 401 TYR A CD2 1 
ATOM   3146 C  CE1 . TYR A 1 401 ? 94.914  91.822  112.963 1.00 73.50  ? 401 TYR A CE1 1 
ATOM   3147 C  CE2 . TYR A 1 401 ? 94.882  89.880  114.344 1.00 73.50  ? 401 TYR A CE2 1 
ATOM   3148 C  CZ  . TYR A 1 401 ? 94.717  91.232  114.182 1.00 73.50  ? 401 TYR A CZ  1 
ATOM   3149 O  OH  . TYR A 1 401 ? 94.349  92.005  115.247 1.00 73.50  ? 401 TYR A OH  1 
ATOM   3150 N  N   . LEU A 1 402 ? 95.012  89.466  107.876 1.00 73.88  ? 402 LEU A N   1 
ATOM   3151 C  CA  . LEU A 1 402 ? 95.613  89.689  106.566 1.00 73.88  ? 402 LEU A CA  1 
ATOM   3152 C  C   . LEU A 1 402 ? 96.515  90.902  106.709 1.00 73.88  ? 402 LEU A C   1 
ATOM   3153 O  O   . LEU A 1 402 ? 96.041  92.036  106.650 1.00 73.88  ? 402 LEU A O   1 
ATOM   3154 C  CB  . LEU A 1 402 ? 94.561  89.924  105.489 1.00 73.88  ? 402 LEU A CB  1 
ATOM   3155 C  CG  . LEU A 1 402 ? 93.538  88.845  105.167 1.00 73.88  ? 402 LEU A CG  1 
ATOM   3156 C  CD1 . LEU A 1 402 ? 92.395  89.460  104.417 1.00 73.88  ? 402 LEU A CD1 1 
ATOM   3157 C  CD2 . LEU A 1 402 ? 94.162  87.773  104.340 1.00 73.88  ? 402 LEU A CD2 1 
ATOM   3158 N  N   . SER A 1 403 ? 97.805  90.676  106.905 1.00 75.60  ? 403 SER A N   1 
ATOM   3159 C  CA  . SER A 1 403 ? 98.747  91.771  107.055 1.00 75.60  ? 403 SER A CA  1 
ATOM   3160 C  C   . SER A 1 403 ? 99.279  92.197  105.701 1.00 75.60  ? 403 SER A C   1 
ATOM   3161 O  O   . SER A 1 403 ? 99.707  91.361  104.906 1.00 75.60  ? 403 SER A O   1 
ATOM   3162 C  CB  . SER A 1 403 ? 99.900  91.387  107.970 1.00 75.60  ? 403 SER A CB  1 
ATOM   3163 O  OG  . SER A 1 403 ? 99.542  91.576  109.321 1.00 75.60  ? 403 SER A OG  1 
ATOM   3164 N  N   . SER A 1 404 ? 99.260  93.500  105.453 1.00 75.59  ? 404 SER A N   1 
ATOM   3165 C  CA  . SER A 1 404 ? 99.728  94.041  104.189 1.00 75.59  ? 404 SER A CA  1 
ATOM   3166 C  C   . SER A 1 404 ? 101.238 93.937  104.088 1.00 75.59  ? 404 SER A C   1 
ATOM   3167 O  O   . SER A 1 404 ? 101.956 94.333  105.004 1.00 75.59  ? 404 SER A O   1 
ATOM   3168 C  CB  . SER A 1 404 ? 99.308  95.497  104.066 1.00 75.59  ? 404 SER A CB  1 
ATOM   3169 O  OG  . SER A 1 404 ? 97.972  95.597  103.630 1.00 75.59  ? 404 SER A OG  1 
ATOM   3170 N  N   . GLU A 1 405 ? 101.724 93.418  102.966 1.00 80.79  ? 405 GLU A N   1 
ATOM   3171 C  CA  . GLU A 1 405 ? 103.154 93.415  102.661 1.00 80.79  ? 405 GLU A CA  1 
ATOM   3172 C  C   . GLU A 1 405 ? 103.338 94.022  101.281 1.00 80.79  ? 405 GLU A C   1 
ATOM   3173 O  O   . GLU A 1 405 ? 103.117 93.369  100.265 1.00 80.79  ? 405 GLU A O   1 
ATOM   3174 C  CB  . GLU A 1 405 ? 103.739 92.034  102.743 1.00 80.79  ? 405 GLU A CB  1 
ATOM   3175 C  CG  . GLU A 1 405 ? 104.123 91.646  104.135 1.00 80.79  ? 405 GLU A CG  1 
ATOM   3176 C  CD  . GLU A 1 405 ? 105.301 90.708  104.172 1.00 80.79  ? 405 GLU A CD  1 
ATOM   3177 O  OE1 . GLU A 1 405 ? 105.667 90.163  103.112 1.00 80.79  ? 405 GLU A OE1 1 
ATOM   3178 O  OE2 . GLU A 1 405 ? 105.875 90.527  105.264 1.00 80.79  ? 405 GLU A OE2 1 
ATOM   3179 N  N   . TYR A 1 406 ? 103.750 95.280  101.249 1.00 75.86  ? 406 TYR A N   1 
ATOM   3180 C  CA  . TYR A 1 406 ? 103.995 95.943  99.982  1.00 75.86  ? 406 TYR A CA  1 
ATOM   3181 C  C   . TYR A 1 406 ? 105.390 95.609  99.482  1.00 75.86  ? 406 TYR A C   1 
ATOM   3182 O  O   . TYR A 1 406 ? 106.375 95.746  100.208 1.00 75.86  ? 406 TYR A O   1 
ATOM   3183 C  CB  . TYR A 1 406 ? 103.825 97.446  100.146 1.00 75.86  ? 406 TYR A CB  1 
ATOM   3184 C  CG  . TYR A 1 406 ? 104.155 98.247  98.921  1.00 75.86  ? 406 TYR A CG  1 
ATOM   3185 C  CD1 . TYR A 1 406 ? 103.426 98.100  97.760  1.00 75.86  ? 406 TYR A CD1 1 
ATOM   3186 C  CD2 . TYR A 1 406 ? 105.193 99.158  98.932  1.00 75.86  ? 406 TYR A CD2 1 
ATOM   3187 C  CE1 . TYR A 1 406 ? 103.725 98.832  96.645  1.00 75.86  ? 406 TYR A CE1 1 
ATOM   3188 C  CE2 . TYR A 1 406 ? 105.496 99.896  97.821  1.00 75.86  ? 406 TYR A CE2 1 
ATOM   3189 C  CZ  . TYR A 1 406 ? 104.758 99.729  96.685  1.00 75.86  ? 406 TYR A CZ  1 
ATOM   3190 O  OH  . TYR A 1 406 ? 105.060 100.464 95.573  1.00 75.86  ? 406 TYR A OH  1 
ATOM   3191 N  N   . GLU A 1 407 ? 105.473 95.181  98.230  1.00 80.30  ? 407 GLU A N   1 
ATOM   3192 C  CA  . GLU A 1 407 ? 106.693 94.651  97.641  1.00 80.30  ? 407 GLU A CA  1 
ATOM   3193 C  C   . GLU A 1 407 ? 107.064 95.443  96.395  1.00 80.30  ? 407 GLU A C   1 
ATOM   3194 O  O   . GLU A 1 407 ? 108.016 95.113  95.685  1.00 80.30  ? 407 GLU A O   1 
ATOM   3195 C  CB  . GLU A 1 407 ? 106.505 93.168  97.323  1.00 80.30  ? 407 GLU A CB  1 
ATOM   3196 C  CG  . GLU A 1 407 ? 107.745 92.317  97.076  1.00 80.30  ? 407 GLU A CG  1 
ATOM   3197 C  CD  . GLU A 1 407 ? 108.534 92.058  98.317  1.00 80.30  ? 407 GLU A CD  1 
ATOM   3198 O  OE1 . GLU A 1 407 ? 107.907 91.826  99.364  1.00 80.30  ? 407 GLU A OE1 1 
ATOM   3199 O  OE2 . GLU A 1 407 ? 109.778 92.080  98.247  1.00 80.30  ? 407 GLU A OE2 1 
ATOM   3200 N  N   . GLY A 1 408 ? 106.339 96.519  96.119  1.00 79.72  ? 408 GLY A N   1 
ATOM   3201 C  CA  . GLY A 1 408 ? 106.504 97.262  94.890  1.00 79.72  ? 408 GLY A CA  1 
ATOM   3202 C  C   . GLY A 1 408 ? 107.749 98.125  94.875  1.00 79.72  ? 408 GLY A C   1 
ATOM   3203 O  O   . GLY A 1 408 ? 108.723 97.889  95.589  1.00 79.72  ? 408 GLY A O   1 
ATOM   3204 N  N   . GLU A 1 409 ? 107.709 99.144  94.026  1.00 82.73  ? 409 GLU A N   1 
ATOM   3205 C  CA  . GLU A 1 409 ? 108.842 100.044 93.901  1.00 82.73  ? 409 GLU A CA  1 
ATOM   3206 C  C   . GLU A 1 409 ? 108.965 100.906 95.144  1.00 82.73  ? 409 GLU A C   1 
ATOM   3207 O  O   . GLU A 1 409 ? 107.974 101.435 95.649  1.00 82.73  ? 409 GLU A O   1 
ATOM   3208 C  CB  . GLU A 1 409 ? 108.686 100.927 92.664  1.00 82.73  ? 409 GLU A CB  1 
ATOM   3209 C  CG  . GLU A 1 409 ? 108.475 100.196 91.330  1.00 82.73  ? 409 GLU A CG  1 
ATOM   3210 C  CD  . GLU A 1 409 ? 109.718 99.529  90.724  1.00 82.73  ? 409 GLU A CD  1 
ATOM   3211 O  OE1 . GLU A 1 409 ? 110.531 98.900  91.434  1.00 82.73  ? 409 GLU A OE1 1 
ATOM   3212 O  OE2 . GLU A 1 409 ? 109.877 99.633  89.489  1.00 82.73  ? 409 GLU A OE2 1 
ATOM   3213 N  N   . ARG A 1 410 ? 110.188 101.047 95.638  1.00 79.67  ? 410 ARG A N   1 
ATOM   3214 C  CA  . ARG A 1 410 ? 110.439 101.832 96.842  1.00 79.67  ? 410 ARG A CA  1 
ATOM   3215 C  C   . ARG A 1 410 ? 110.687 103.298 96.500  1.00 79.67  ? 410 ARG A C   1 
ATOM   3216 O  O   . ARG A 1 410 ? 111.695 103.890 96.866  1.00 79.67  ? 410 ARG A O   1 
ATOM   3217 C  CB  . ARG A 1 410 ? 111.607 101.243 97.617  1.00 79.67  ? 410 ARG A CB  1 
ATOM   3218 C  CG  . ARG A 1 410 ? 111.480 99.770  97.888  1.00 79.67  ? 410 ARG A CG  1 
ATOM   3219 C  CD  . ARG A 1 410 ? 110.290 99.483  98.754  1.00 79.67  ? 410 ARG A CD  1 
ATOM   3220 N  NE  . ARG A 1 410 ? 110.237 98.083  99.141  1.00 79.67  ? 410 ARG A NE  1 
ATOM   3221 C  CZ  . ARG A 1 410 ? 109.249 97.546  99.838  1.00 79.67  ? 410 ARG A CZ  1 
ATOM   3222 N  NH1 . ARG A 1 410 ? 108.235 98.296  100.229 1.00 79.67  ? 410 ARG A NH1 1 
ATOM   3223 N  NH2 . ARG A 1 410 ? 109.280 96.265  100.153 1.00 79.67  ? 410 ARG A NH2 1 
ATOM   3224 N  N   . GLU A 1 411 ? 109.756 103.869 95.763  1.00 82.79  ? 411 GLU A N   1 
ATOM   3225 C  CA  . GLU A 1 411 ? 109.677 105.305 95.616  1.00 82.79  ? 411 GLU A CA  1 
ATOM   3226 C  C   . GLU A 1 411 ? 109.289 105.913 96.961  1.00 82.79  ? 411 GLU A C   1 
ATOM   3227 O  O   . GLU A 1 411 ? 108.519 105.303 97.705  1.00 82.79  ? 411 GLU A O   1 
ATOM   3228 C  CB  . GLU A 1 411 ? 108.643 105.650 94.549  1.00 82.79  ? 411 GLU A CB  1 
ATOM   3229 C  CG  . GLU A 1 411 ? 108.622 107.077 94.063  1.00 82.79  ? 411 GLU A CG  1 
ATOM   3230 C  CD  . GLU A 1 411 ? 107.349 107.400 93.308  1.00 82.79  ? 411 GLU A CD  1 
ATOM   3231 O  OE1 . GLU A 1 411 ? 106.884 106.541 92.531  1.00 82.79  ? 411 GLU A OE1 1 
ATOM   3232 O  OE2 . GLU A 1 411 ? 106.808 108.509 93.493  1.00 82.79  ? 411 GLU A OE2 1 
ATOM   3233 N  N   . PRO A 1 412 ? 109.844 107.069 97.325  1.00 77.16  ? 412 PRO A N   1 
ATOM   3234 C  CA  . PRO A 1 412 ? 109.526 107.663 98.630  1.00 77.16  ? 412 PRO A CA  1 
ATOM   3235 C  C   . PRO A 1 412 ? 108.067 108.083 98.738  1.00 77.16  ? 412 PRO A C   1 
ATOM   3236 O  O   . PRO A 1 412 ? 107.513 108.702 97.830  1.00 77.16  ? 412 PRO A O   1 
ATOM   3237 C  CB  . PRO A 1 412 ? 110.469 108.865 98.701  1.00 77.16  ? 412 PRO A CB  1 
ATOM   3238 C  CG  . PRO A 1 412 ? 111.587 108.509 97.834  1.00 77.16  ? 412 PRO A CG  1 
ATOM   3239 C  CD  . PRO A 1 412 ? 111.020 107.709 96.716  1.00 77.16  ? 412 PRO A CD  1 
ATOM   3240 N  N   . TRP A 1 413 ? 107.448 107.703 99.856  1.00 73.67  ? 413 TRP A N   1 
ATOM   3241 C  CA  . TRP A 1 413 ? 106.045 107.859 100.258 1.00 73.67  ? 413 TRP A CA  1 
ATOM   3242 C  C   . TRP A 1 413 ? 105.077 107.094 99.373  1.00 73.67  ? 413 TRP A C   1 
ATOM   3243 O  O   . TRP A 1 413 ? 103.873 107.280 99.523  1.00 73.67  ? 413 TRP A O   1 
ATOM   3244 C  CB  . TRP A 1 413 ? 105.573 109.320 100.316 1.00 73.67  ? 413 TRP A CB  1 
ATOM   3245 C  CG  . TRP A 1 413 ? 106.267 110.100 101.342 1.00 73.67  ? 413 TRP A CG  1 
ATOM   3246 C  CD1 . TRP A 1 413 ? 105.958 110.179 102.655 1.00 73.67  ? 413 TRP A CD1 1 
ATOM   3247 C  CD2 . TRP A 1 413 ? 107.414 110.911 101.147 1.00 73.67  ? 413 TRP A CD2 1 
ATOM   3248 N  NE1 . TRP A 1 413 ? 106.841 110.997 103.299 1.00 73.67  ? 413 TRP A NE1 1 
ATOM   3249 C  CE2 . TRP A 1 413 ? 107.748 111.460 102.388 1.00 73.67  ? 413 TRP A CE2 1 
ATOM   3250 C  CE3 . TRP A 1 413 ? 108.189 111.233 100.037 1.00 73.67  ? 413 TRP A CE3 1 
ATOM   3251 C  CZ2 . TRP A 1 413 ? 108.821 112.308 102.551 1.00 73.67  ? 413 TRP A CZ2 1 
ATOM   3252 C  CZ3 . TRP A 1 413 ? 109.256 112.055 100.202 1.00 73.67  ? 413 TRP A CZ3 1 
ATOM   3253 C  CH2 . TRP A 1 413 ? 109.572 112.578 101.449 1.00 73.67  ? 413 TRP A CH2 1 
ATOM   3254 N  N   . ARG A 1 414 ? 105.548 106.240 98.469  1.00 75.04  ? 414 ARG A N   1 
ATOM   3255 C  CA  . ARG A 1 414 ? 104.632 105.498 97.618  1.00 75.04  ? 414 ARG A CA  1 
ATOM   3256 C  C   . ARG A 1 414 ? 103.931 104.402 98.404  1.00 75.04  ? 414 ARG A C   1 
ATOM   3257 O  O   . ARG A 1 414 ? 102.777 104.068 98.124  1.00 75.04  ? 414 ARG A O   1 
ATOM   3258 C  CB  . ARG A 1 414 ? 105.388 104.917 96.427  1.00 75.04  ? 414 ARG A CB  1 
ATOM   3259 C  CG  . ARG A 1 414 ? 104.496 104.291 95.395  1.00 75.04  ? 414 ARG A CG  1 
ATOM   3260 C  CD  . ARG A 1 414 ? 105.265 103.689 94.257  1.00 75.04  ? 414 ARG A CD  1 
ATOM   3261 N  NE  . ARG A 1 414 ? 104.574 102.527 93.714  1.00 75.04  ? 414 ARG A NE  1 
ATOM   3262 C  CZ  . ARG A 1 414 ? 103.590 102.586 92.826  1.00 75.04  ? 414 ARG A CZ  1 
ATOM   3263 N  NH1 . ARG A 1 414 ? 103.172 103.751 92.367  1.00 75.04  ? 414 ARG A NH1 1 
ATOM   3264 N  NH2 . ARG A 1 414 ? 103.022 101.473 92.396  1.00 75.04  ? 414 ARG A NH2 1 
ATOM   3265 N  N   . SER A 1 415 ? 104.600 103.868 99.424  1.00 74.76  ? 415 SER A N   1 
ATOM   3266 C  CA  . SER A 1 415 ? 104.070 102.728 100.158 1.00 74.76  ? 415 SER A CA  1 
ATOM   3267 C  C   . SER A 1 415 ? 102.904 103.108 101.053 1.00 74.76  ? 415 SER A C   1 
ATOM   3268 O  O   . SER A 1 415 ? 102.121 102.240 101.441 1.00 74.76  ? 415 SER A O   1 
ATOM   3269 C  CB  . SER A 1 415 ? 105.175 102.102 100.992 1.00 74.76  ? 415 SER A CB  1 
ATOM   3270 O  OG  . SER A 1 415 ? 105.768 103.067 101.832 1.00 74.76  ? 415 SER A OG  1 
ATOM   3271 N  N   . ILE A 1 416 ? 102.779 104.385 101.407 1.00 73.26  ? 416 ILE A N   1 
ATOM   3272 C  CA  . ILE A 1 416 ? 101.667 104.818 102.247 1.00 73.26  ? 416 ILE A CA  1 
ATOM   3273 C  C   . ILE A 1 416 ? 100.361 104.727 101.476 1.00 73.26  ? 416 ILE A C   1 
ATOM   3274 O  O   . ILE A 1 416 ? 99.355  104.220 101.979 1.00 73.26  ? 416 ILE A O   1 
ATOM   3275 C  CB  . ILE A 1 416 ? 101.915 106.242 102.766 1.00 73.26  ? 416 ILE A CB  1 
ATOM   3276 C  CG1 . ILE A 1 416 ? 103.216 106.298 103.553 1.00 73.26  ? 416 ILE A CG1 1 
ATOM   3277 C  CG2 . ILE A 1 416 ? 100.774 106.697 103.637 1.00 73.26  ? 416 ILE A CG2 1 
ATOM   3278 C  CD1 . ILE A 1 416 ? 103.637 107.689 103.897 1.00 73.26  ? 416 ILE A CD1 1 
ATOM   3279 N  N   . GLU A 1 417 ? 100.371 105.186 100.231 1.00 73.16  ? 417 GLU A N   1 
ATOM   3280 C  CA  . GLU A 1 417 ? 99.161  105.170 99.425  1.00 73.16  ? 417 GLU A CA  1 
ATOM   3281 C  C   . GLU A 1 417 ? 98.832  103.763 98.951  1.00 73.16  ? 417 GLU A C   1 
ATOM   3282 O  O   . GLU A 1 417 ? 97.661  103.428 98.758  1.00 73.16  ? 417 GLU A O   1 
ATOM   3283 C  CB  . GLU A 1 417 ? 99.330  106.124 98.245  1.00 73.16  ? 417 GLU A CB  1 
ATOM   3284 C  CG  . GLU A 1 417 ? 98.098  106.330 97.396  1.00 73.16  ? 417 GLU A CG  1 
ATOM   3285 C  CD  . GLU A 1 417 ? 96.966  106.971 98.155  1.00 73.16  ? 417 GLU A CD  1 
ATOM   3286 O  OE1 . GLU A 1 417 ? 97.224  107.861 98.984  1.00 73.16  ? 417 GLU A OE1 1 
ATOM   3287 O  OE2 . GLU A 1 417 ? 95.811  106.578 97.926  1.00 73.16  ? 417 GLU A OE2 1 
ATOM   3288 N  N   . GLN A 1 418 ? 99.845  102.916 98.790  1.00 73.94  ? 418 GLN A N   1 
ATOM   3289 C  CA  . GLN A 1 418 ? 99.614  101.585 98.244  1.00 73.94  ? 418 GLN A CA  1 
ATOM   3290 C  C   . GLN A 1 418 ? 98.962  100.668 99.267  1.00 73.94  ? 418 GLN A C   1 
ATOM   3291 O  O   . GLN A 1 418 ? 98.125  99.832  98.918  1.00 73.94  ? 418 GLN A O   1 
ATOM   3292 C  CB  . GLN A 1 418 ? 100.926 100.993 97.747  1.00 73.94  ? 418 GLN A CB  1 
ATOM   3293 C  CG  . GLN A 1 418 ? 101.410 101.600 96.460  1.00 73.94  ? 418 GLN A CG  1 
ATOM   3294 C  CD  . GLN A 1 418 ? 100.498 101.305 95.304  1.00 73.94  ? 418 GLN A CD  1 
ATOM   3295 O  OE1 . GLN A 1 418 ? 100.253 100.153 94.978  1.00 73.94  ? 418 GLN A OE1 1 
ATOM   3296 N  NE2 . GLN A 1 418 ? 99.991  102.346 94.674  1.00 73.94  ? 418 GLN A NE2 1 
ATOM   3297 N  N   . VAL A 1 419 ? 99.332  100.807 100.538 1.00 71.75  ? 419 VAL A N   1 
ATOM   3298 C  CA  . VAL A 1 419 ? 98.723  99.992  101.583 1.00 71.75  ? 419 VAL A CA  1 
ATOM   3299 C  C   . VAL A 1 419 ? 97.284  100.433 101.826 1.00 71.75  ? 419 VAL A C   1 
ATOM   3300 O  O   . VAL A 1 419 ? 96.409  99.611  102.116 1.00 71.75  ? 419 VAL A O   1 
ATOM   3301 C  CB  . VAL A 1 419 ? 99.592  100.049 102.855 1.00 71.75  ? 419 VAL A CB  1 
ATOM   3302 C  CG1 . VAL A 1 419 ? 98.950  99.351  104.020 1.00 71.75  ? 419 VAL A CG1 1 
ATOM   3303 C  CG2 . VAL A 1 419 ? 100.919 99.404  102.587 1.00 71.75  ? 419 VAL A CG2 1 
ATOM   3304 N  N   . ARG A 1 420 ? 97.006  101.728 101.656 1.00 70.18  ? 420 ARG A N   1 
ATOM   3305 C  CA  . ARG A 1 420 ? 95.635  102.222 101.748 1.00 70.18  ? 420 ARG A CA  1 
ATOM   3306 C  C   . ARG A 1 420 ? 94.769  101.663 100.635 1.00 70.18  ? 420 ARG A C   1 
ATOM   3307 O  O   . ARG A 1 420 ? 93.583  101.392 100.839 1.00 70.18  ? 420 ARG A O   1 
ATOM   3308 C  CB  . ARG A 1 420 ? 95.614  103.743 101.693 1.00 70.18  ? 420 ARG A CB  1 
ATOM   3309 C  CG  . ARG A 1 420 ? 96.152  104.415 102.905 1.00 70.18  ? 420 ARG A CG  1 
ATOM   3310 C  CD  . ARG A 1 420 ? 95.970  105.905 102.828 1.00 70.18  ? 420 ARG A CD  1 
ATOM   3311 N  NE  . ARG A 1 420 ? 94.604  106.323 103.108 1.00 70.18  ? 420 ARG A NE  1 
ATOM   3312 C  CZ  . ARG A 1 420 ? 94.120  106.527 104.325 1.00 70.18  ? 420 ARG A CZ  1 
ATOM   3313 N  NH1 . ARG A 1 420 ? 94.884  106.343 105.386 1.00 70.18  ? 420 ARG A NH1 1 
ATOM   3314 N  NH2 . ARG A 1 420 ? 92.870  106.917 104.483 1.00 70.18  ? 420 ARG A NH2 1 
ATOM   3315 N  N   . ARG A 1 421 ? 95.346  101.482 99.451  1.00 73.23  ? 421 ARG A N   1 
ATOM   3316 C  CA  . ARG A 1 421 ? 94.580  100.965 98.329  1.00 73.23  ? 421 ARG A CA  1 
ATOM   3317 C  C   . ARG A 1 421 ? 94.294  99.486  98.494  1.00 73.23  ? 421 ARG A C   1 
ATOM   3318 O  O   . ARG A 1 421 ? 93.293  98.983  97.981  1.00 73.23  ? 421 ARG A O   1 
ATOM   3319 C  CB  . ARG A 1 421 ? 95.329  101.221 97.030  1.00 73.23  ? 421 ARG A CB  1 
ATOM   3320 C  CG  . ARG A 1 421 ? 95.245  102.638 96.586  1.00 73.23  ? 421 ARG A CG  1 
ATOM   3321 C  CD  . ARG A 1 421 ? 96.060  102.895 95.367  1.00 73.23  ? 421 ARG A CD  1 
ATOM   3322 N  NE  . ARG A 1 421 ? 96.159  104.322 95.131  1.00 73.23  ? 421 ARG A NE  1 
ATOM   3323 C  CZ  . ARG A 1 421 ? 96.827  104.866 94.130  1.00 73.23  ? 421 ARG A CZ  1 
ATOM   3324 N  NH1 . ARG A 1 421 ? 97.460  104.097 93.263  1.00 73.23  ? 421 ARG A NH1 1 
ATOM   3325 N  NH2 . ARG A 1 421 ? 96.862  106.179 93.999  1.00 73.23  ? 421 ARG A NH2 1 
ATOM   3326 N  N   . GLN A 1 422 ? 95.154  98.773  99.215  1.00 74.55  ? 422 GLN A N   1 
ATOM   3327 C  CA  . GLN A 1 422 ? 94.953  97.341  99.372  1.00 74.55  ? 422 GLN A CA  1 
ATOM   3328 C  C   . GLN A 1 422 ? 93.880  97.045  100.403 1.00 74.55  ? 422 GLN A C   1 
ATOM   3329 O  O   . GLN A 1 422 ? 93.083  96.121  100.228 1.00 74.55  ? 422 GLN A O   1 
ATOM   3330 C  CB  . GLN A 1 422 ? 96.251  96.662  99.765  1.00 74.55  ? 422 GLN A CB  1 
ATOM   3331 C  CG  . GLN A 1 422 ? 96.235  95.197  99.468  1.00 74.55  ? 422 GLN A CG  1 
ATOM   3332 C  CD  . GLN A 1 422 ? 97.095  94.427  100.409 1.00 74.55  ? 422 GLN A CD  1 
ATOM   3333 O  OE1 . GLN A 1 422 ? 97.336  94.855  101.526 1.00 74.55  ? 422 GLN A OE1 1 
ATOM   3334 N  NE2 . GLN A 1 422 ? 97.582  93.290  99.963  1.00 74.55  ? 422 GLN A NE2 1 
ATOM   3335 N  N   . HIS A 1 423 ? 93.858  97.803  101.496 1.00 73.51  ? 423 HIS A N   1 
ATOM   3336 C  CA  . HIS A 1 423 ? 92.821  97.616  102.499 1.00 73.51  ? 423 HIS A CA  1 
ATOM   3337 C  C   . HIS A 1 423 ? 91.472  98.072  101.977 1.00 73.51  ? 423 HIS A C   1 
ATOM   3338 O  O   . HIS A 1 423 ? 90.438  97.509  102.338 1.00 73.51  ? 423 HIS A O   1 
ATOM   3339 C  CB  . HIS A 1 423 ? 93.185  98.369  103.769 1.00 73.51  ? 423 HIS A CB  1 
ATOM   3340 C  CG  . HIS A 1 423 ? 94.120  97.621  104.661 1.00 73.51  ? 423 HIS A CG  1 
ATOM   3341 N  ND1 . HIS A 1 423 ? 93.730  97.096  105.870 1.00 73.51  ? 423 HIS A ND1 1 
ATOM   3342 C  CD2 . HIS A 1 423 ? 95.425  97.303  104.515 1.00 73.51  ? 423 HIS A CD2 1 
ATOM   3343 C  CE1 . HIS A 1 423 ? 94.757  96.488  106.433 1.00 73.51  ? 423 HIS A CE1 1 
ATOM   3344 N  NE2 . HIS A 1 423 ? 95.797  96.599  105.630 1.00 73.51  ? 423 HIS A NE2 1 
ATOM   3345 N  N   . SER A 1 424 ? 91.466  99.087  101.119 1.00 74.89  ? 424 SER A N   1 
ATOM   3346 C  CA  . SER A 1 424 ? 90.225  99.514  100.491 1.00 74.89  ? 424 SER A CA  1 
ATOM   3347 C  C   . SER A 1 424 ? 89.735  98.483  99.489  1.00 74.89  ? 424 SER A C   1 
ATOM   3348 O  O   . SER A 1 424 ? 88.529  98.292  99.326  1.00 74.89  ? 424 SER A O   1 
ATOM   3349 C  CB  . SER A 1 424 ? 90.425  100.861 99.813  1.00 74.89  ? 424 SER A CB  1 
ATOM   3350 O  OG  . SER A 1 424 ? 89.187  101.407 99.416  1.00 74.89  ? 424 SER A OG  1 
ATOM   3351 N  N   . LEU A 1 425 ? 90.656  97.800  98.814  1.00 76.04  ? 425 LEU A N   1 
ATOM   3352 C  CA  . LEU A 1 425 ? 90.260  96.820  97.812  1.00 76.04  ? 425 LEU A CA  1 
ATOM   3353 C  C   . LEU A 1 425 ? 89.789  95.526  98.457  1.00 76.04  ? 425 LEU A C   1 
ATOM   3354 O  O   . LEU A 1 425 ? 88.803  94.929  98.018  1.00 76.04  ? 425 LEU A O   1 
ATOM   3355 C  CB  . LEU A 1 425 ? 91.421  96.550  96.859  1.00 76.04  ? 425 LEU A CB  1 
ATOM   3356 C  CG  . LEU A 1 425 ? 91.302  95.368  95.901  1.00 76.04  ? 425 LEU A CG  1 
ATOM   3357 C  CD1 . LEU A 1 425 ? 90.196  95.609  94.910  1.00 76.04  ? 425 LEU A CD1 1 
ATOM   3358 C  CD2 . LEU A 1 425 ? 92.606  95.143  95.189  1.00 76.04  ? 425 LEU A CD2 1 
ATOM   3359 N  N   . ILE A 1 426 ? 90.481  95.079  99.504  1.00 75.96  ? 426 ILE A N   1 
ATOM   3360 C  CA  . ILE A 1 426 ? 90.170  93.790  100.110 1.00 75.96  ? 426 ILE A CA  1 
ATOM   3361 C  C   . ILE A 1 426 ? 88.869  93.863  100.898 1.00 75.96  ? 426 ILE A C   1 
ATOM   3362 O  O   . ILE A 1 426 ? 88.032  92.957  100.820 1.00 75.96  ? 426 ILE A O   1 
ATOM   3363 C  CB  . ILE A 1 426 ? 91.352  93.327  100.977 1.00 75.96  ? 426 ILE A CB  1 
ATOM   3364 C  CG1 . ILE A 1 426 ? 92.492  92.854  100.089 1.00 75.96  ? 426 ILE A CG1 1 
ATOM   3365 C  CG2 . ILE A 1 426 ? 90.966  92.206  101.902 1.00 75.96  ? 426 ILE A CG2 1 
ATOM   3366 C  CD1 . ILE A 1 426 ? 93.739  92.535  100.849 1.00 75.96  ? 426 ILE A CD1 1 
ATOM   3367 N  N   . ARG A 1 427 ? 88.656  94.956  101.632 1.00 77.49  ? 427 ARG A N   1 
ATOM   3368 C  CA  . ARG A 1 427 ? 87.432  95.103  102.413 1.00 77.49  ? 427 ARG A CA  1 
ATOM   3369 C  C   . ARG A 1 427 ? 86.216  95.284  101.518 1.00 77.49  ? 427 ARG A C   1 
ATOM   3370 O  O   . ARG A 1 427 ? 85.098  94.929  101.900 1.00 77.49  ? 427 ARG A O   1 
ATOM   3371 C  CB  . ARG A 1 427 ? 87.558  96.282  103.369 1.00 77.49  ? 427 ARG A CB  1 
ATOM   3372 C  CG  . ARG A 1 427 ? 88.412  96.020  104.577 1.00 77.49  ? 427 ARG A CG  1 
ATOM   3373 C  CD  . ARG A 1 427 ? 88.832  97.318  105.204 1.00 77.49  ? 427 ARG A CD  1 
ATOM   3374 N  NE  . ARG A 1 427 ? 89.213  97.170  106.597 1.00 77.49  ? 427 ARG A NE  1 
ATOM   3375 C  CZ  . ARG A 1 427 ? 88.377  97.336  107.610 1.00 77.49  ? 427 ARG A CZ  1 
ATOM   3376 N  NH1 . ARG A 1 427 ? 87.114  97.648  107.378 1.00 77.49  ? 427 ARG A NH1 1 
ATOM   3377 N  NH2 . ARG A 1 427 ? 88.800  97.181  108.853 1.00 77.49  ? 427 ARG A NH2 1 
ATOM   3378 N  N   . GLN A 1 428 ? 86.410  95.832  100.322 1.00 79.91  ? 428 GLN A N   1 
ATOM   3379 C  CA  . GLN A 1 428 ? 85.292  95.969  99.401  1.00 79.91  ? 428 GLN A CA  1 
ATOM   3380 C  C   . GLN A 1 428 ? 84.958  94.644  98.741  1.00 79.91  ? 428 GLN A C   1 
ATOM   3381 O  O   . GLN A 1 428 ? 83.799  94.392  98.402  1.00 79.91  ? 428 GLN A O   1 
ATOM   3382 C  CB  . GLN A 1 428 ? 85.608  97.020  98.349  1.00 79.91  ? 428 GLN A CB  1 
ATOM   3383 C  CG  . GLN A 1 428 ? 85.295  98.417  98.789  1.00 79.91  ? 428 GLN A CG  1 
ATOM   3384 C  CD  . GLN A 1 428 ? 85.566  99.423  97.711  1.00 79.91  ? 428 GLN A CD  1 
ATOM   3385 O  OE1 . GLN A 1 428 ? 86.618  100.053 97.684  1.00 79.91  ? 428 GLN A OE1 1 
ATOM   3386 N  NE2 . GLN A 1 428 ? 84.614  99.585  96.807  1.00 79.91  ? 428 GLN A NE2 1 
ATOM   3387 N  N   . ILE A 1 429 ? 85.961  93.792  98.537  1.00 80.51  ? 429 ILE A N   1 
ATOM   3388 C  CA  . ILE A 1 429 ? 85.712  92.470  97.977  1.00 80.51  ? 429 ILE A CA  1 
ATOM   3389 C  C   . ILE A 1 429 ? 85.014  91.588  99.001  1.00 80.51  ? 429 ILE A C   1 
ATOM   3390 O  O   . ILE A 1 429 ? 84.063  90.867  98.676  1.00 80.51  ? 429 ILE A O   1 
ATOM   3391 C  CB  . ILE A 1 429 ? 87.034  91.855  97.484  1.00 80.51  ? 429 ILE A CB  1 
ATOM   3392 C  CG1 . ILE A 1 429 ? 87.472  92.525  96.193  1.00 80.51  ? 429 ILE A CG1 1 
ATOM   3393 C  CG2 . ILE A 1 429 ? 86.907  90.375  97.236  1.00 80.51  ? 429 ILE A CG2 1 
ATOM   3394 C  CD1 . ILE A 1 429 ? 88.838  92.125  95.752  1.00 80.51  ? 429 ILE A CD1 1 
ATOM   3395 N  N   . ALA A 1 430 ? 85.426  91.684  100.265 1.00 82.29  ? 430 ALA A N   1 
ATOM   3396 C  CA  . ALA A 1 430 ? 84.871  90.825  101.304 1.00 82.29  ? 430 ALA A CA  1 
ATOM   3397 C  C   . ALA A 1 430 ? 83.436  91.199  101.646 1.00 82.29  ? 430 ALA A C   1 
ATOM   3398 O  O   . ALA A 1 430 ? 82.716  90.406  102.258 1.00 82.29  ? 430 ALA A O   1 
ATOM   3399 C  CB  . ALA A 1 430 ? 85.743  90.885  102.552 1.00 82.29  ? 430 ALA A CB  1 
ATOM   3400 N  N   . ASP A 1 431 ? 83.002  92.405  101.278 1.00 87.15  ? 431 ASP A N   1 
ATOM   3401 C  CA  . ASP A 1 431 ? 81.588  92.735  101.409 1.00 87.15  ? 431 ASP A CA  1 
ATOM   3402 C  C   . ASP A 1 431 ? 80.811  92.338  100.168 1.00 87.15  ? 431 ASP A C   1 
ATOM   3403 O  O   . ASP A 1 431 ? 79.595  92.130  100.229 1.00 87.15  ? 431 ASP A O   1 
ATOM   3404 C  CB  . ASP A 1 431 ? 81.404  94.218  101.689 1.00 87.15  ? 431 ASP A CB  1 
ATOM   3405 C  CG  . ASP A 1 431 ? 81.835  94.593  103.077 1.00 87.15  ? 431 ASP A CG  1 
ATOM   3406 O  OD1 . ASP A 1 431 ? 82.012  93.673  103.895 1.00 87.15  ? 431 ASP A OD1 1 
ATOM   3407 O  OD2 . ASP A 1 431 ? 81.944  95.796  103.364 1.00 87.15  ? 431 ASP A OD2 1 
ATOM   3408 N  N   . ARG A 1 432 ? 81.493  92.224  99.032  1.00 88.00  ? 432 ARG A N   1 
ATOM   3409 C  CA  . ARG A 1 432 ? 80.819  91.767  97.827  1.00 88.00  ? 432 ARG A CA  1 
ATOM   3410 C  C   . ARG A 1 432 ? 80.541  90.273  97.896  1.00 88.00  ? 432 ARG A C   1 
ATOM   3411 O  O   . ARG A 1 432 ? 79.666  89.764  97.187  1.00 88.00  ? 432 ARG A O   1 
ATOM   3412 C  CB  . ARG A 1 432 ? 81.656  92.108  96.601  1.00 88.00  ? 432 ARG A CB  1 
ATOM   3413 C  CG  . ARG A 1 432 ? 80.845  92.613  95.435  1.00 88.00  ? 432 ARG A CG  1 
ATOM   3414 C  CD  . ARG A 1 432 ? 81.677  92.746  94.166  1.00 88.00  ? 432 ARG A CD  1 
ATOM   3415 N  NE  . ARG A 1 432 ? 83.055  93.173  94.404  1.00 88.00  ? 432 ARG A NE  1 
ATOM   3416 C  CZ  . ARG A 1 432 ? 83.433  94.434  94.590  1.00 88.00  ? 432 ARG A CZ  1 
ATOM   3417 N  NH1 . ARG A 1 432 ? 82.538  95.410  94.584  1.00 88.00  ? 432 ARG A NH1 1 
ATOM   3418 N  NH2 . ARG A 1 432 ? 84.709  94.722  94.787  1.00 88.00  ? 432 ARG A NH2 1 
ATOM   3419 N  N   . LEU A 1 433 ? 81.270  89.554  98.742  1.00 85.53  ? 433 LEU A N   1 
ATOM   3420 C  CA  . LEU A 1 433 ? 81.008  88.141  98.960  1.00 85.53  ? 433 LEU A CA  1 
ATOM   3421 C  C   . LEU A 1 433 ? 79.962  87.954  100.045 1.00 85.53  ? 433 LEU A C   1 
ATOM   3422 O  O   . LEU A 1 433 ? 79.153  87.036  99.983  1.00 85.53  ? 433 LEU A O   1 
ATOM   3423 C  CB  . LEU A 1 433 ? 82.289  87.408  99.338  1.00 85.53  ? 433 LEU A CB  1 
ATOM   3424 C  CG  . LEU A 1 433 ? 83.467  87.574  98.383  1.00 85.53  ? 433 LEU A CG  1 
ATOM   3425 C  CD1 . LEU A 1 433 ? 84.736  87.094  99.041  1.00 85.53  ? 433 LEU A CD1 1 
ATOM   3426 C  CD2 . LEU A 1 433 ? 83.224  86.834  97.087  1.00 85.53  ? 433 LEU A CD2 1 
ATOM   3427 N  N   . MET B 1 1   ? 117.749 109.801 114.835 1.00 86.14  ? 1   MET B N   1 
ATOM   3428 C  CA  . MET B 1 1   ? 118.121 110.566 113.655 1.00 86.14  ? 1   MET B CA  1 
ATOM   3429 C  C   . MET B 1 1   ? 117.749 109.818 112.389 1.00 86.14  ? 1   MET B C   1 
ATOM   3430 O  O   . MET B 1 1   ? 117.888 108.603 112.312 1.00 86.14  ? 1   MET B O   1 
ATOM   3431 C  CB  . MET B 1 1   ? 119.616 110.872 113.665 1.00 86.14  ? 1   MET B CB  1 
ATOM   3432 C  CG  . MET B 1 1   ? 119.975 112.175 114.347 1.00 86.14  ? 1   MET B CG  1 
ATOM   3433 S  SD  . MET B 1 1   ? 121.747 112.458 114.411 1.00 86.14  ? 1   MET B SD  1 
ATOM   3434 C  CE  . MET B 1 1   ? 122.214 111.968 112.756 1.00 86.14  ? 1   MET B CE  1 
ATOM   3435 N  N   . LEU B 1 2   ? 117.277 110.557 111.394 1.00 78.44  ? 2   LEU B N   1 
ATOM   3436 C  CA  . LEU B 1 2   ? 116.872 109.964 110.136 1.00 78.44  ? 2   LEU B CA  1 
ATOM   3437 C  C   . LEU B 1 2   ? 118.041 109.933 109.160 1.00 78.44  ? 2   LEU B C   1 
ATOM   3438 O  O   . LEU B 1 2   ? 119.037 110.638 109.322 1.00 78.44  ? 2   LEU B O   1 
ATOM   3439 C  CB  . LEU B 1 2   ? 115.703 110.744 109.546 1.00 78.44  ? 2   LEU B CB  1 
ATOM   3440 C  CG  . LEU B 1 2   ? 114.415 110.665 110.359 1.00 78.44  ? 2   LEU B CG  1 
ATOM   3441 C  CD1 . LEU B 1 2   ? 113.589 111.900 110.147 1.00 78.44  ? 2   LEU B CD1 1 
ATOM   3442 C  CD2 . LEU B 1 2   ? 113.622 109.440 109.976 1.00 78.44  ? 2   LEU B CD2 1 
ATOM   3443 N  N   . LEU B 1 3   ? 117.910 109.098 108.139 1.00 74.43  ? 3   LEU B N   1 
ATOM   3444 C  CA  . LEU B 1 3   ? 118.930 108.929 107.118 1.00 74.43  ? 3   LEU B CA  1 
ATOM   3445 C  C   . LEU B 1 3   ? 118.366 109.320 105.759 1.00 74.43  ? 3   LEU B C   1 
ATOM   3446 O  O   . LEU B 1 3   ? 117.187 109.634 105.624 1.00 74.43  ? 3   LEU B O   1 
ATOM   3447 C  CB  . LEU B 1 3   ? 119.441 107.486 107.105 1.00 74.43  ? 3   LEU B CB  1 
ATOM   3448 C  CG  . LEU B 1 3   ? 120.087 107.035 108.415 1.00 74.43  ? 3   LEU B CG  1 
ATOM   3449 C  CD1 . LEU B 1 3   ? 120.143 105.537 108.521 1.00 74.43  ? 3   LEU B CD1 1 
ATOM   3450 C  CD2 . LEU B 1 3   ? 121.467 107.605 108.539 1.00 74.43  ? 3   LEU B CD2 1 
ATOM   3451 N  N   . GLU B 1 4   ? 119.225 109.319 104.748 1.00 76.93  ? 4   GLU B N   1 
ATOM   3452 C  CA  . GLU B 1 4   ? 118.818 109.664 103.396 1.00 76.93  ? 4   GLU B CA  1 
ATOM   3453 C  C   . GLU B 1 4   ? 118.513 108.404 102.595 1.00 76.93  ? 4   GLU B C   1 
ATOM   3454 O  O   . GLU B 1 4   ? 118.865 107.298 102.998 1.00 76.93  ? 4   GLU B O   1 
ATOM   3455 C  CB  . GLU B 1 4   ? 119.911 110.475 102.716 1.00 76.93  ? 4   GLU B CB  1 
ATOM   3456 C  CG  . GLU B 1 4   ? 120.455 111.581 103.587 1.00 76.93  ? 4   GLU B CG  1 
ATOM   3457 C  CD  . GLU B 1 4   ? 121.756 112.152 103.070 1.00 76.93  ? 4   GLU B CD  1 
ATOM   3458 O  OE1 . GLU B 1 4   ? 122.672 112.385 103.887 1.00 76.93  ? 4   GLU B OE1 1 
ATOM   3459 O  OE2 . GLU B 1 4   ? 121.864 112.369 101.846 1.00 76.93  ? 4   GLU B OE2 1 
ATOM   3460 N  N   . ARG B 1 5   ? 117.846 108.572 101.448 1.00 77.34  ? 5   ARG B N   1 
ATOM   3461 C  CA  . ARG B 1 5   ? 117.517 107.404 100.631 1.00 77.34  ? 5   ARG B CA  1 
ATOM   3462 C  C   . ARG B 1 5   ? 118.743 106.833 99.948  1.00 77.34  ? 5   ARG B C   1 
ATOM   3463 O  O   . ARG B 1 5   ? 118.798 105.630 99.673  1.00 77.34  ? 5   ARG B O   1 
ATOM   3464 C  CB  . ARG B 1 5   ? 116.475 107.725 99.570  1.00 77.34  ? 5   ARG B CB  1 
ATOM   3465 C  CG  . ARG B 1 5   ? 115.128 107.905 100.100 1.00 77.34  ? 5   ARG B CG  1 
ATOM   3466 C  CD  . ARG B 1 5   ? 114.529 106.682 100.705 1.00 77.34  ? 5   ARG B CD  1 
ATOM   3467 N  NE  . ARG B 1 5   ? 113.756 105.914 99.749  1.00 77.34  ? 5   ARG B NE  1 
ATOM   3468 C  CZ  . ARG B 1 5   ? 112.516 105.511 99.986  1.00 77.34  ? 5   ARG B CZ  1 
ATOM   3469 N  NH1 . ARG B 1 5   ? 111.923 105.840 101.119 1.00 77.34  ? 5   ARG B NH1 1 
ATOM   3470 N  NH2 . ARG B 1 5   ? 111.862 104.805 99.087  1.00 77.34  ? 5   ARG B NH2 1 
ATOM   3471 N  N   . ASP B 1 6   ? 119.703 107.682 99.608  1.00 77.39  ? 6   ASP B N   1 
ATOM   3472 C  CA  . ASP B 1 6   ? 120.937 107.188 99.029  1.00 77.39  ? 6   ASP B CA  1 
ATOM   3473 C  C   . ASP B 1 6   ? 121.695 106.381 100.065 1.00 77.39  ? 6   ASP B C   1 
ATOM   3474 O  O   . ASP B 1 6   ? 121.677 106.704 101.253 1.00 77.39  ? 6   ASP B O   1 
ATOM   3475 C  CB  . ASP B 1 6   ? 121.789 108.343 98.525  1.00 77.39  ? 6   ASP B CB  1 
ATOM   3476 C  CG  . ASP B 1 6   ? 121.070 109.184 97.506  1.00 77.39  ? 6   ASP B CG  1 
ATOM   3477 O  OD1 . ASP B 1 6   ? 120.887 110.392 97.750  1.00 77.39  ? 6   ASP B OD1 1 
ATOM   3478 O  OD2 . ASP B 1 6   ? 120.671 108.635 96.462  1.00 77.39  ? 6   ASP B OD2 1 
ATOM   3479 N  N   . LEU B 1 7   ? 122.305 105.287 99.611  1.00 72.09  ? 7   LEU B N   1 
ATOM   3480 C  CA  . LEU B 1 7   ? 123.090 104.451 100.506 1.00 72.09  ? 7   LEU B CA  1 
ATOM   3481 C  C   . LEU B 1 7   ? 124.282 105.216 101.046 1.00 72.09  ? 7   LEU B C   1 
ATOM   3482 O  O   . LEU B 1 7   ? 124.526 105.233 102.253 1.00 72.09  ? 7   LEU B O   1 
ATOM   3483 C  CB  . LEU B 1 7   ? 123.543 103.195 99.775  1.00 72.09  ? 7   LEU B CB  1 
ATOM   3484 C  CG  . LEU B 1 7   ? 122.460 102.221 99.334  1.00 72.09  ? 7   LEU B CG  1 
ATOM   3485 C  CD1 . LEU B 1 7   ? 123.120 100.925 98.959  1.00 72.09  ? 7   LEU B CD1 1 
ATOM   3486 C  CD2 . LEU B 1 7   ? 121.434 102.005 100.422 1.00 72.09  ? 7   LEU B CD2 1 
ATOM   3487 N  N   . ILE B 1 8   ? 125.011 105.891 100.169 1.00 71.20  ? 8   ILE B N   1 
ATOM   3488 C  CA  . ILE B 1 8   ? 126.082 106.773 100.599 1.00 71.20  ? 8   ILE B CA  1 
ATOM   3489 C  C   . ILE B 1 8   ? 125.467 108.037 101.175 1.00 71.20  ? 8   ILE B C   1 
ATOM   3490 O  O   . ILE B 1 8   ? 124.712 108.740 100.498 1.00 71.20  ? 8   ILE B O   1 
ATOM   3491 C  CB  . ILE B 1 8   ? 127.021 107.091 99.432  1.00 71.20  ? 8   ILE B CB  1 
ATOM   3492 C  CG1 . ILE B 1 8   ? 127.503 105.799 98.788  1.00 71.20  ? 8   ILE B CG1 1 
ATOM   3493 C  CG2 . ILE B 1 8   ? 128.185 107.912 99.909  1.00 71.20  ? 8   ILE B CG2 1 
ATOM   3494 C  CD1 . ILE B 1 8   ? 128.150 105.997 97.463  1.00 71.20  ? 8   ILE B CD1 1 
ATOM   3495 N  N   . GLN B 1 9   ? 125.767 108.320 102.431 1.00 71.20  ? 9   GLN B N   1 
ATOM   3496 C  CA  . GLN B 1 9   ? 125.254 109.508 103.083 1.00 71.20  ? 9   GLN B CA  1 
ATOM   3497 C  C   . GLN B 1 9   ? 126.196 110.672 102.840 1.00 71.20  ? 9   GLN B C   1 
ATOM   3498 O  O   . GLN B 1 9   ? 127.412 110.497 102.745 1.00 71.20  ? 9   GLN B O   1 
ATOM   3499 C  CB  . GLN B 1 9   ? 125.091 109.273 104.581 1.00 71.20  ? 9   GLN B CB  1 
ATOM   3500 C  CG  . GLN B 1 9   ? 124.396 107.988 104.924 1.00 71.20  ? 9   GLN B CG  1 
ATOM   3501 C  CD  . GLN B 1 9   ? 122.913 108.080 104.743 1.00 71.20  ? 9   GLN B CD  1 
ATOM   3502 O  OE1 . GLN B 1 9   ? 122.241 108.814 105.454 1.00 71.20  ? 9   GLN B OE1 1 
ATOM   3503 N  NE2 . GLN B 1 9   ? 122.387 107.340 103.787 1.00 71.20  ? 9   GLN B NE2 1 
ATOM   3504 N  N   . SER B 1 10  ? 125.629 111.868 102.732 1.00 71.49  ? 10  SER B N   1 
ATOM   3505 C  CA  . SER B 1 10  ? 126.468 113.045 102.564 1.00 71.49  ? 10  SER B CA  1 
ATOM   3506 C  C   . SER B 1 10  ? 127.112 113.451 103.879 1.00 71.49  ? 10  SER B C   1 
ATOM   3507 O  O   . SER B 1 10  ? 128.278 113.846 103.908 1.00 71.49  ? 10  SER B O   1 
ATOM   3508 C  CB  . SER B 1 10  ? 125.650 114.194 101.992 1.00 71.49  ? 10  SER B CB  1 
ATOM   3509 O  OG  . SER B 1 10  ? 125.203 113.886 100.688 1.00 71.49  ? 10  SER B OG  1 
ATOM   3510 N  N   . VAL B 1 11  ? 126.371 113.346 104.976 1.00 70.46  ? 11  VAL B N   1 
ATOM   3511 C  CA  . VAL B 1 11  ? 126.891 113.718 106.282 1.00 70.46  ? 11  VAL B CA  1 
ATOM   3512 C  C   . VAL B 1 11  ? 127.862 112.653 106.764 1.00 70.46  ? 11  VAL B C   1 
ATOM   3513 O  O   . VAL B 1 11  ? 127.538 111.461 106.795 1.00 70.46  ? 11  VAL B O   1 
ATOM   3514 C  CB  . VAL B 1 11  ? 125.730 113.908 107.268 1.00 70.46  ? 11  VAL B CB  1 
ATOM   3515 C  CG1 . VAL B 1 11  ? 126.236 114.304 108.627 1.00 70.46  ? 11  VAL B CG1 1 
ATOM   3516 C  CG2 . VAL B 1 11  ? 124.777 114.943 106.738 1.00 70.46  ? 11  VAL B CG2 1 
ATOM   3517 N  N   . GLY B 1 12  ? 129.068 113.077 107.135 1.00 70.09  ? 12  GLY B N   1 
ATOM   3518 C  CA  . GLY B 1 12  ? 130.083 112.184 107.657 1.00 70.09  ? 12  GLY B CA  1 
ATOM   3519 C  C   . GLY B 1 12  ? 131.195 111.860 106.683 1.00 70.09  ? 12  GLY B C   1 
ATOM   3520 O  O   . GLY B 1 12  ? 132.124 111.136 107.044 1.00 70.09  ? 12  GLY B O   1 
ATOM   3521 N  N   . PHE B 1 13  ? 131.121 112.373 105.461 1.00 68.98  ? 13  PHE B N   1 
ATOM   3522 C  CA  . PHE B 1 13  ? 132.181 112.186 104.477 1.00 68.98  ? 13  PHE B CA  1 
ATOM   3523 C  C   . PHE B 1 13  ? 133.308 113.162 104.780 1.00 68.98  ? 13  PHE B C   1 
ATOM   3524 O  O   . PHE B 1 13  ? 133.307 114.289 104.286 1.00 68.98  ? 13  PHE B O   1 
ATOM   3525 C  CB  . PHE B 1 13  ? 131.623 112.384 103.073 1.00 68.98  ? 13  PHE B CB  1 
ATOM   3526 C  CG  . PHE B 1 13  ? 132.617 112.150 101.980 1.00 68.98  ? 13  PHE B CG  1 
ATOM   3527 C  CD1 . PHE B 1 13  ? 133.492 111.088 102.033 1.00 68.98  ? 13  PHE B CD1 1 
ATOM   3528 C  CD2 . PHE B 1 13  ? 132.668 112.992 100.891 1.00 68.98  ? 13  PHE B CD2 1 
ATOM   3529 C  CE1 . PHE B 1 13  ? 134.400 110.880 101.029 1.00 68.98  ? 13  PHE B CE1 1 
ATOM   3530 C  CE2 . PHE B 1 13  ? 133.577 112.789 99.889  1.00 68.98  ? 13  PHE B CE2 1 
ATOM   3531 C  CZ  . PHE B 1 13  ? 134.439 111.731 99.957  1.00 68.98  ? 13  PHE B CZ  1 
ATOM   3532 N  N   . ARG B 1 14  ? 134.265 112.738 105.602 1.00 72.90  ? 14  ARG B N   1 
ATOM   3533 C  CA  . ARG B 1 14  ? 135.301 113.622 106.122 1.00 72.90  ? 14  ARG B CA  1 
ATOM   3534 C  C   . ARG B 1 14  ? 136.656 112.995 105.852 1.00 72.90  ? 14  ARG B C   1 
ATOM   3535 O  O   . ARG B 1 14  ? 136.753 111.870 105.369 1.00 72.90  ? 14  ARG B O   1 
ATOM   3536 C  CB  . ARG B 1 14  ? 135.160 113.841 107.627 1.00 72.90  ? 14  ARG B CB  1 
ATOM   3537 C  CG  . ARG B 1 14  ? 133.767 113.788 108.167 1.00 72.90  ? 14  ARG B CG  1 
ATOM   3538 C  CD  . ARG B 1 14  ? 133.765 113.842 109.665 1.00 72.90  ? 14  ARG B CD  1 
ATOM   3539 N  NE  . ARG B 1 14  ? 133.930 115.208 110.130 1.00 72.90  ? 14  ARG B NE  1 
ATOM   3540 C  CZ  . ARG B 1 14  ? 135.047 115.666 110.670 1.00 72.90  ? 14  ARG B CZ  1 
ATOM   3541 N  NH1 . ARG B 1 14  ? 136.086 114.859 110.814 1.00 72.90  ? 14  ARG B NH1 1 
ATOM   3542 N  NH2 . ARG B 1 14  ? 135.128 116.925 111.064 1.00 72.90  ? 14  ARG B NH2 1 
ATOM   3543 N  N   . ASN B 1 15  ? 137.703 113.728 106.200 1.00 74.27  ? 15  ASN B N   1 
ATOM   3544 C  CA  . ASN B 1 15  ? 139.034 113.174 106.380 1.00 74.27  ? 15  ASN B CA  1 
ATOM   3545 C  C   . ASN B 1 15  ? 139.232 112.816 107.845 1.00 74.27  ? 15  ASN B C   1 
ATOM   3546 O  O   . ASN B 1 15  ? 138.676 113.456 108.737 1.00 74.27  ? 15  ASN B O   1 
ATOM   3547 C  CB  . ASN B 1 15  ? 140.102 114.171 105.942 1.00 74.27  ? 15  ASN B CB  1 
ATOM   3548 C  CG  . ASN B 1 15  ? 140.346 114.143 104.466 1.00 74.27  ? 15  ASN B CG  1 
ATOM   3549 O  OD1 . ASN B 1 15  ? 140.104 113.143 103.812 1.00 74.27  ? 15  ASN B OD1 1 
ATOM   3550 N  ND2 . ASN B 1 15  ? 140.825 115.245 103.927 1.00 74.27  ? 15  ASN B ND2 1 
ATOM   3551 N  N   . VAL B 1 16  ? 140.034 111.788 108.092 1.00 78.58  ? 16  VAL B N   1 
ATOM   3552 C  CA  . VAL B 1 16  ? 140.245 111.257 109.433 1.00 78.58  ? 16  VAL B CA  1 
ATOM   3553 C  C   . VAL B 1 16  ? 141.671 111.567 109.858 1.00 78.58  ? 16  VAL B C   1 
ATOM   3554 O  O   . VAL B 1 16  ? 142.619 111.282 109.122 1.00 78.58  ? 16  VAL B O   1 
ATOM   3555 C  CB  . VAL B 1 16  ? 139.965 109.747 109.489 1.00 78.58  ? 16  VAL B CB  1 
ATOM   3556 C  CG1 . VAL B 1 16  ? 140.283 109.196 110.852 1.00 78.58  ? 16  VAL B CG1 1 
ATOM   3557 C  CG2 . VAL B 1 16  ? 138.528 109.481 109.157 1.00 78.58  ? 16  VAL B CG2 1 
ATOM   3558 N  N   . ARG B 1 17  ? 141.820 112.151 111.042 1.00 89.21  ? 17  ARG B N   1 
ATOM   3559 C  CA  . ARG B 1 17  ? 143.118 112.512 111.591 1.00 89.21  ? 17  ARG B CA  1 
ATOM   3560 C  C   . ARG B 1 17  ? 143.405 111.657 112.813 1.00 89.21  ? 17  ARG B C   1 
ATOM   3561 O  O   . ARG B 1 17  ? 142.542 111.499 113.680 1.00 89.21  ? 17  ARG B O   1 
ATOM   3562 C  CB  . ARG B 1 17  ? 143.160 113.991 111.952 1.00 89.21  ? 17  ARG B CB  1 
ATOM   3563 C  CG  . ARG B 1 17  ? 143.055 114.877 110.749 1.00 89.21  ? 17  ARG B CG  1 
ATOM   3564 C  CD  . ARG B 1 17  ? 142.773 116.298 111.126 1.00 89.21  ? 17  ARG B CD  1 
ATOM   3565 N  NE  . ARG B 1 17  ? 142.921 117.178 109.977 1.00 89.21  ? 17  ARG B NE  1 
ATOM   3566 C  CZ  . ARG B 1 17  ? 144.074 117.712 109.595 1.00 89.21  ? 17  ARG B CZ  1 
ATOM   3567 N  NH1 . ARG B 1 17  ? 145.183 117.458 110.274 1.00 89.21  ? 17  ARG B NH1 1 
ATOM   3568 N  NH2 . ARG B 1 17  ? 144.117 118.504 108.536 1.00 89.21  ? 17  ARG B NH2 1 
ATOM   3569 N  N   . GLU B 1 18  ? 144.612 111.103 112.877 1.00 96.80  ? 18  GLU B N   1 
ATOM   3570 C  CA  . GLU B 1 18  ? 145.058 110.326 114.026 1.00 96.80  ? 18  GLU B CA  1 
ATOM   3571 C  C   . GLU B 1 18  ? 146.441 110.806 114.428 1.00 96.80  ? 18  GLU B C   1 
ATOM   3572 O  O   . GLU B 1 18  ? 147.429 110.483 113.763 1.00 96.80  ? 18  GLU B O   1 
ATOM   3573 C  CB  . GLU B 1 18  ? 145.083 108.832 113.711 1.00 96.80  ? 18  GLU B CB  1 
ATOM   3574 C  CG  . GLU B 1 18  ? 143.725 108.167 113.771 1.00 96.80  ? 18  GLU B CG  1 
ATOM   3575 C  CD  . GLU B 1 18  ? 143.734 106.780 113.167 1.00 96.80  ? 18  GLU B CD  1 
ATOM   3576 O  OE1 . GLU B 1 18  ? 143.125 106.589 112.092 1.00 96.80  ? 18  GLU B OE1 1 
ATOM   3577 O  OE2 . GLU B 1 18  ? 144.358 105.879 113.766 1.00 96.80  ? 18  GLU B OE2 1 
ATOM   3578 N  N   . GLY B 1 19  ? 146.510 111.564 115.516 1.00 99.89  ? 19  GLY B N   1 
ATOM   3579 C  CA  . GLY B 1 19  ? 147.780 112.105 115.949 1.00 99.89  ? 19  GLY B CA  1 
ATOM   3580 C  C   . GLY B 1 19  ? 148.296 113.247 115.110 1.00 99.89  ? 19  GLY B C   1 
ATOM   3581 O  O   . GLY B 1 19  ? 149.509 113.371 114.929 1.00 99.89  ? 19  GLY B O   1 
ATOM   3582 N  N   . GLY B 1 20  ? 147.410 114.084 114.580 1.00 99.06  ? 20  GLY B N   1 
ATOM   3583 C  CA  . GLY B 1 20  ? 147.821 115.194 113.748 1.00 99.06  ? 20  GLY B CA  1 
ATOM   3584 C  C   . GLY B 1 20  ? 148.128 114.839 112.314 1.00 99.06  ? 20  GLY B C   1 
ATOM   3585 O  O   . GLY B 1 20  ? 148.428 115.737 111.521 1.00 99.06  ? 20  GLY B O   1 
ATOM   3586 N  N   . GLU B 1 21  ? 148.059 113.563 111.953 1.00 95.19  ? 21  GLU B N   1 
ATOM   3587 C  CA  . GLU B 1 21  ? 148.292 113.107 110.593 1.00 95.19  ? 21  GLU B CA  1 
ATOM   3588 C  C   . GLU B 1 21  ? 146.968 112.676 109.990 1.00 95.19  ? 21  GLU B C   1 
ATOM   3589 O  O   . GLU B 1 21  ? 146.210 111.941 110.626 1.00 95.19  ? 21  GLU B O   1 
ATOM   3590 C  CB  . GLU B 1 21  ? 149.274 111.936 110.566 1.00 95.19  ? 21  GLU B CB  1 
ATOM   3591 C  CG  . GLU B 1 21  ? 150.670 112.273 111.025 1.00 95.19  ? 21  GLU B CG  1 
ATOM   3592 C  CD  . GLU B 1 21  ? 151.394 113.178 110.056 1.00 95.19  ? 21  GLU B CD  1 
ATOM   3593 O  OE1 . GLU B 1 21  ? 151.136 113.072 108.840 1.00 95.19  ? 21  GLU B OE1 1 
ATOM   3594 O  OE2 . GLU B 1 21  ? 152.225 113.993 110.507 1.00 95.19  ? 21  GLU B OE2 1 
ATOM   3595 N  N   . ILE B 1 22  ? 146.690 113.126 108.770 1.00 84.25  ? 22  ILE B N   1 
ATOM   3596 C  CA  . ILE B 1 22  ? 145.543 112.599 108.048 1.00 84.25  ? 22  ILE B CA  1 
ATOM   3597 C  C   . ILE B 1 22  ? 145.880 111.208 107.541 1.00 84.25  ? 22  ILE B C   1 
ATOM   3598 O  O   . ILE B 1 22  ? 146.724 111.042 106.653 1.00 84.25  ? 22  ILE B O   1 
ATOM   3599 C  CB  . ILE B 1 22  ? 145.145 113.527 106.896 1.00 84.25  ? 22  ILE B CB  1 
ATOM   3600 C  CG1 . ILE B 1 22  ? 144.909 114.939 107.410 1.00 84.25  ? 22  ILE B CG1 1 
ATOM   3601 C  CG2 . ILE B 1 22  ? 143.896 113.013 106.232 1.00 84.25  ? 22  ILE B CG2 1 
ATOM   3602 C  CD1 . ILE B 1 22  ? 144.581 115.915 106.327 1.00 84.25  ? 22  ILE B CD1 1 
ATOM   3603 N  N   . THR B 1 23  ? 145.230 110.199 108.112 1.00 81.32  ? 23  THR B N   1 
ATOM   3604 C  CA  . THR B 1 23  ? 145.518 108.818 107.775 1.00 81.32  ? 23  THR B CA  1 
ATOM   3605 C  C   . THR B 1 23  ? 144.587 108.237 106.730 1.00 81.32  ? 23  THR B C   1 
ATOM   3606 O  O   . THR B 1 23  ? 144.917 107.208 106.141 1.00 81.32  ? 23  THR B O   1 
ATOM   3607 C  CB  . THR B 1 23  ? 145.454 107.940 109.029 1.00 81.32  ? 23  THR B CB  1 
ATOM   3608 O  OG1 . THR B 1 23  ? 144.148 108.029 109.604 1.00 81.32  ? 23  THR B OG1 1 
ATOM   3609 C  CG2 . THR B 1 23  ? 146.471 108.399 110.044 1.00 81.32  ? 23  THR B CG2 1 
ATOM   3610 N  N   . GLY B 1 24  ? 143.445 108.864 106.485 1.00 74.92  ? 24  GLY B N   1 
ATOM   3611 C  CA  . GLY B 1 24  ? 142.495 108.338 105.531 1.00 74.92  ? 24  GLY B CA  1 
ATOM   3612 C  C   . GLY B 1 24  ? 141.250 109.192 105.530 1.00 74.92  ? 24  GLY B C   1 
ATOM   3613 O  O   . GLY B 1 24  ? 141.244 110.297 106.063 1.00 74.92  ? 24  GLY B O   1 
ATOM   3614 N  N   . PHE B 1 25  ? 140.202 108.664 104.922 1.00 69.39  ? 25  PHE B N   1 
ATOM   3615 C  CA  . PHE B 1 25  ? 138.921 109.341 104.902 1.00 69.39  ? 25  PHE B CA  1 
ATOM   3616 C  C   . PHE B 1 25  ? 137.840 108.358 105.311 1.00 69.39  ? 25  PHE B C   1 
ATOM   3617 O  O   . PHE B 1 25  ? 138.037 107.145 105.296 1.00 69.39  ? 25  PHE B O   1 
ATOM   3618 C  CB  . PHE B 1 25  ? 138.628 109.966 103.529 1.00 69.39  ? 25  PHE B CB  1 
ATOM   3619 C  CG  . PHE B 1 25  ? 138.376 108.974 102.438 1.00 69.39  ? 25  PHE B CG  1 
ATOM   3620 C  CD1 . PHE B 1 25  ? 139.427 108.386 101.770 1.00 69.39  ? 25  PHE B CD1 1 
ATOM   3621 C  CD2 . PHE B 1 25  ? 137.087 108.661 102.053 1.00 69.39  ? 25  PHE B CD2 1 
ATOM   3622 C  CE1 . PHE B 1 25  ? 139.198 107.490 100.770 1.00 69.39  ? 25  PHE B CE1 1 
ATOM   3623 C  CE2 . PHE B 1 25  ? 136.858 107.761 101.053 1.00 69.39  ? 25  PHE B CE2 1 
ATOM   3624 C  CZ  . PHE B 1 25  ? 137.914 107.180 100.409 1.00 69.39  ? 25  PHE B CZ  1 
ATOM   3625 N  N   . GLN B 1 26  ? 136.688 108.895 105.685 1.00 69.74  ? 26  GLN B N   1 
ATOM   3626 C  CA  . GLN B 1 26  ? 135.570 108.075 106.108 1.00 69.74  ? 26  GLN B CA  1 
ATOM   3627 C  C   . GLN B 1 26  ? 134.306 108.544 105.415 1.00 69.74  ? 26  GLN B C   1 
ATOM   3628 O  O   . GLN B 1 26  ? 134.240 109.652 104.887 1.00 69.74  ? 26  GLN B O   1 
ATOM   3629 C  CB  . GLN B 1 26  ? 135.376 108.117 107.619 1.00 69.74  ? 26  GLN B CB  1 
ATOM   3630 C  CG  . GLN B 1 26  ? 134.917 109.450 108.120 1.00 69.74  ? 26  GLN B CG  1 
ATOM   3631 C  CD  . GLN B 1 26  ? 134.343 109.378 109.500 1.00 69.74  ? 26  GLN B CD  1 
ATOM   3632 O  OE1 . GLN B 1 26  ? 135.017 108.978 110.441 1.00 69.74  ? 26  GLN B OE1 1 
ATOM   3633 N  NE2 . GLN B 1 26  ? 133.090 109.771 109.636 1.00 69.74  ? 26  GLN B NE2 1 
ATOM   3634 N  N   . PHE B 1 27  ? 133.305 107.670 105.410 1.00 66.33  ? 27  PHE B N   1 
ATOM   3635 C  CA  . PHE B 1 27  ? 131.969 108.013 104.953 1.00 66.33  ? 27  PHE B CA  1 
ATOM   3636 C  C   . PHE B 1 27  ? 130.995 107.057 105.615 1.00 66.33  ? 27  PHE B C   1 
ATOM   3637 O  O   . PHE B 1 27  ? 131.389 106.035 106.172 1.00 66.33  ? 27  PHE B O   1 
ATOM   3638 C  CB  . PHE B 1 27  ? 131.838 107.975 103.423 1.00 66.33  ? 27  PHE B CB  1 
ATOM   3639 C  CG  . PHE B 1 27  ? 132.181 106.656 102.800 1.00 66.33  ? 27  PHE B CG  1 
ATOM   3640 C  CD1 . PHE B 1 27  ? 133.487 106.336 102.497 1.00 66.33  ? 27  PHE B CD1 1 
ATOM   3641 C  CD2 . PHE B 1 27  ? 131.191 105.754 102.477 1.00 66.33  ? 27  PHE B CD2 1 
ATOM   3642 C  CE1 . PHE B 1 27  ? 133.797 105.141 101.923 1.00 66.33  ? 27  PHE B CE1 1 
ATOM   3643 C  CE2 . PHE B 1 27  ? 131.505 104.556 101.897 1.00 66.33  ? 27  PHE B CE2 1 
ATOM   3644 C  CZ  . PHE B 1 27  ? 132.804 104.252 101.622 1.00 66.33  ? 27  PHE B CZ  1 
ATOM   3645 N  N   . ARG B 1 28  ? 129.717 107.404 105.562 1.00 68.00  ? 28  ARG B N   1 
ATOM   3646 C  CA  . ARG B 1 28  ? 128.673 106.628 106.210 1.00 68.00  ? 28  ARG B CA  1 
ATOM   3647 C  C   . ARG B 1 28  ? 127.761 105.995 105.172 1.00 68.00  ? 28  ARG B C   1 
ATOM   3648 O  O   . ARG B 1 28  ? 127.414 106.625 104.173 1.00 68.00  ? 28  ARG B O   1 
ATOM   3649 C  CB  . ARG B 1 28  ? 127.863 107.497 107.167 1.00 68.00  ? 28  ARG B CB  1 
ATOM   3650 C  CG  . ARG B 1 28  ? 128.635 107.921 108.392 1.00 68.00  ? 28  ARG B CG  1 
ATOM   3651 C  CD  . ARG B 1 28  ? 127.982 109.085 109.089 1.00 68.00  ? 28  ARG B CD  1 
ATOM   3652 N  NE  . ARG B 1 28  ? 126.702 108.727 109.680 1.00 68.00  ? 28  ARG B NE  1 
ATOM   3653 C  CZ  . ARG B 1 28  ? 125.544 109.268 109.330 1.00 68.00  ? 28  ARG B CZ  1 
ATOM   3654 N  NH1 . ARG B 1 28  ? 125.503 110.193 108.390 1.00 68.00  ? 28  ARG B NH1 1 
ATOM   3655 N  NH2 . ARG B 1 28  ? 124.428 108.881 109.919 1.00 68.00  ? 28  ARG B NH2 1 
ATOM   3656 N  N   . VAL B 1 29  ? 127.388 104.741 105.408 1.00 68.46  ? 29  VAL B N   1 
ATOM   3657 C  CA  . VAL B 1 29  ? 126.561 103.965 104.492 1.00 68.46  ? 29  VAL B CA  1 
ATOM   3658 C  C   . VAL B 1 29  ? 125.292 103.548 105.213 1.00 68.46  ? 29  VAL B C   1 
ATOM   3659 O  O   . VAL B 1 29  ? 125.352 102.987 106.310 1.00 68.46  ? 29  VAL B O   1 
ATOM   3660 C  CB  . VAL B 1 29  ? 127.293 102.720 103.962 1.00 68.46  ? 29  VAL B CB  1 
ATOM   3661 C  CG1 . VAL B 1 29  ? 126.494 102.073 102.865 1.00 68.46  ? 29  VAL B CG1 1 
ATOM   3662 C  CG2 . VAL B 1 29  ? 128.639 103.074 103.444 1.00 68.46  ? 29  VAL B CG2 1 
ATOM   3663 N  N   . ARG B 1 30  ? 124.149 103.810 104.593 1.00 72.24  ? 30  ARG B N   1 
ATOM   3664 C  CA  . ARG B 1 30  ? 122.893 103.255 105.062 1.00 72.24  ? 30  ARG B CA  1 
ATOM   3665 C  C   . ARG B 1 30  ? 122.815 101.779 104.713 1.00 72.24  ? 30  ARG B C   1 
ATOM   3666 O  O   . ARG B 1 30  ? 123.319 101.341 103.679 1.00 72.24  ? 30  ARG B O   1 
ATOM   3667 C  CB  . ARG B 1 30  ? 121.723 103.994 104.428 1.00 72.24  ? 30  ARG B CB  1 
ATOM   3668 C  CG  . ARG B 1 30  ? 120.442 103.917 105.200 1.00 72.24  ? 30  ARG B CG  1 
ATOM   3669 C  CD  . ARG B 1 30  ? 119.288 104.376 104.357 1.00 72.24  ? 30  ARG B CD  1 
ATOM   3670 N  NE  . ARG B 1 30  ? 118.549 103.257 103.799 1.00 72.24  ? 30  ARG B NE  1 
ATOM   3671 C  CZ  . ARG B 1 30  ? 118.048 103.232 102.574 1.00 72.24  ? 30  ARG B CZ  1 
ATOM   3672 N  NH1 . ARG B 1 30  ? 118.214 104.263 101.773 1.00 72.24  ? 30  ARG B NH1 1 
ATOM   3673 N  NH2 . ARG B 1 30  ? 117.389 102.170 102.149 1.00 72.24  ? 30  ARG B NH2 1 
ATOM   3674 N  N   . MET B 1 31  ? 122.187 101.011 105.588 1.00 74.04  ? 31  MET B N   1 
ATOM   3675 C  CA  . MET B 1 31  ? 121.999 99.590  105.346 1.00 74.04  ? 31  MET B CA  1 
ATOM   3676 C  C   . MET B 1 31  ? 121.018 99.389  104.198 1.00 74.04  ? 31  MET B C   1 
ATOM   3677 O  O   . MET B 1 31  ? 119.880 99.866  104.278 1.00 74.04  ? 31  MET B O   1 
ATOM   3678 C  CB  . MET B 1 31  ? 121.497 98.901  106.608 1.00 74.04  ? 31  MET B CB  1 
ATOM   3679 C  CG  . MET B 1 31  ? 120.951 97.514  106.387 1.00 74.04  ? 31  MET B CG  1 
ATOM   3680 S  SD  . MET B 1 31  ? 122.182 96.313  105.878 1.00 74.04  ? 31  MET B SD  1 
ATOM   3681 C  CE  . MET B 1 31  ? 122.736 95.718  107.459 1.00 74.04  ? 31  MET B CE  1 
ATOM   3682 N  N   . PRO B 1 32  ? 121.419 98.728  103.111 1.00 73.23  ? 32  PRO B N   1 
ATOM   3683 C  CA  . PRO B 1 32  ? 120.508 98.613  101.968 1.00 73.23  ? 32  PRO B CA  1 
ATOM   3684 C  C   . PRO B 1 32  ? 119.407 97.601  102.178 1.00 73.23  ? 32  PRO B C   1 
ATOM   3685 O  O   . PRO B 1 32  ? 118.364 97.688  101.523 1.00 73.23  ? 32  PRO B O   1 
ATOM   3686 C  CB  . PRO B 1 32  ? 121.444 98.198  100.833 1.00 73.23  ? 32  PRO B CB  1 
ATOM   3687 C  CG  . PRO B 1 32  ? 122.534 97.495  101.506 1.00 73.23  ? 32  PRO B CG  1 
ATOM   3688 C  CD  . PRO B 1 32  ? 122.744 98.170  102.809 1.00 73.23  ? 32  PRO B CD  1 
ATOM   3689 N  N   . SER B 1 33  ? 119.608 96.639  103.070 1.00 75.59  ? 33  SER B N   1 
ATOM   3690 C  CA  . SER B 1 33  ? 118.632 95.590  103.276 1.00 75.59  ? 33  SER B CA  1 
ATOM   3691 C  C   . SER B 1 33  ? 117.450 96.110  104.086 1.00 75.59  ? 33  SER B C   1 
ATOM   3692 O  O   . SER B 1 33  ? 117.420 97.253  104.542 1.00 75.59  ? 33  SER B O   1 
ATOM   3693 C  CB  . SER B 1 33  ? 119.276 94.403  103.980 1.00 75.59  ? 33  SER B CB  1 
ATOM   3694 O  OG  . SER B 1 33  ? 118.293 93.531  104.495 1.00 75.59  ? 33  SER B OG  1 
ATOM   3695 N  N   . TYR B 1 34  ? 116.459 95.247  104.267 1.00 77.23  ? 34  TYR B N   1 
ATOM   3696 C  CA  . TYR B 1 34  ? 115.286 95.600  105.050 1.00 77.23  ? 34  TYR B CA  1 
ATOM   3697 C  C   . TYR B 1 34  ? 115.477 95.324  106.528 1.00 77.23  ? 34  TYR B C   1 
ATOM   3698 O  O   . TYR B 1 34  ? 114.601 95.654  107.326 1.00 77.23  ? 34  TYR B O   1 
ATOM   3699 C  CB  . TYR B 1 34  ? 114.053 94.861  104.539 1.00 77.23  ? 34  TYR B CB  1 
ATOM   3700 C  CG  . TYR B 1 34  ? 114.285 93.413  104.233 1.00 77.23  ? 34  TYR B CG  1 
ATOM   3701 C  CD1 . TYR B 1 34  ? 114.224 92.460  105.232 1.00 77.23  ? 34  TYR B CD1 1 
ATOM   3702 C  CD2 . TYR B 1 34  ? 114.548 92.995  102.943 1.00 77.23  ? 34  TYR B CD2 1 
ATOM   3703 C  CE1 . TYR B 1 34  ? 114.435 91.140  104.959 1.00 77.23  ? 34  TYR B CE1 1 
ATOM   3704 C  CE2 . TYR B 1 34  ? 114.759 91.676  102.661 1.00 77.23  ? 34  TYR B CE2 1 
ATOM   3705 C  CZ  . TYR B 1 34  ? 114.699 90.753  103.673 1.00 77.23  ? 34  TYR B CZ  1 
ATOM   3706 O  OH  . TYR B 1 34  ? 114.904 89.431  103.394 1.00 77.23  ? 34  TYR B OH  1 
ATOM   3707 N  N   . ARG B 1 35  ? 116.594 94.723  106.908 1.00 74.36  ? 35  ARG B N   1 
ATOM   3708 C  CA  . ARG B 1 35  ? 116.879 94.455  108.303 1.00 74.36  ? 35  ARG B CA  1 
ATOM   3709 C  C   . ARG B 1 35  ? 118.314 94.843  108.587 1.00 74.36  ? 35  ARG B C   1 
ATOM   3710 O  O   . ARG B 1 35  ? 119.117 94.994  107.668 1.00 74.36  ? 35  ARG B O   1 
ATOM   3711 C  CB  . ARG B 1 35  ? 116.663 92.981  108.650 1.00 74.36  ? 35  ARG B CB  1 
ATOM   3712 C  CG  . ARG B 1 35  ? 117.766 92.084  108.156 1.00 74.36  ? 35  ARG B CG  1 
ATOM   3713 C  CD  . ARG B 1 35  ? 117.458 90.650  108.410 1.00 74.36  ? 35  ARG B CD  1 
ATOM   3714 N  NE  . ARG B 1 35  ? 118.364 89.760  107.702 1.00 74.36  ? 35  ARG B NE  1 
ATOM   3715 C  CZ  . ARG B 1 35  ? 119.221 88.948  108.300 1.00 74.36  ? 35  ARG B CZ  1 
ATOM   3716 N  NH1 . ARG B 1 35  ? 119.289 88.914  109.617 1.00 74.36  ? 35  ARG B NH1 1 
ATOM   3717 N  NH2 . ARG B 1 35  ? 120.003 88.166  107.578 1.00 74.36  ? 35  ARG B NH2 1 
ATOM   3718 N  N   . GLY B 1 36  ? 118.616 95.047  109.861 1.00 73.85  ? 36  GLY B N   1 
ATOM   3719 C  CA  . GLY B 1 36  ? 119.994 95.042  110.288 1.00 73.85  ? 36  GLY B CA  1 
ATOM   3720 C  C   . GLY B 1 36  ? 120.440 93.634  110.620 1.00 73.85  ? 36  GLY B C   1 
ATOM   3721 O  O   . GLY B 1 36  ? 119.655 92.802  111.057 1.00 73.85  ? 36  GLY B O   1 
ATOM   3722 N  N   . MET B 1 37  ? 121.716 93.354  110.404 1.00 74.25  ? 37  MET B N   1 
ATOM   3723 C  CA  . MET B 1 37  ? 122.191 91.998  110.590 1.00 74.25  ? 37  MET B CA  1 
ATOM   3724 C  C   . MET B 1 37  ? 123.455 92.005  111.425 1.00 74.25  ? 37  MET B C   1 
ATOM   3725 O  O   . MET B 1 37  ? 124.013 93.054  111.743 1.00 74.25  ? 37  MET B O   1 
ATOM   3726 C  CB  . MET B 1 37  ? 122.436 91.299  109.254 1.00 74.25  ? 37  MET B CB  1 
ATOM   3727 C  CG  . MET B 1 37  ? 123.186 92.126  108.251 1.00 74.25  ? 37  MET B CG  1 
ATOM   3728 S  SD  . MET B 1 37  ? 123.106 91.388  106.619 1.00 74.25  ? 37  MET B SD  1 
ATOM   3729 C  CE  . MET B 1 37  ? 121.467 91.879  106.127 1.00 74.25  ? 37  MET B CE  1 
ATOM   3730 N  N   . ALA B 1 38  ? 123.888 90.805  111.792 1.00 72.87  ? 38  ALA B N   1 
ATOM   3731 C  CA  . ALA B 1 38  ? 125.152 90.649  112.488 1.00 72.87  ? 38  ALA B CA  1 
ATOM   3732 C  C   . ALA B 1 38  ? 126.299 91.010  111.561 1.00 72.87  ? 38  ALA B C   1 
ATOM   3733 O  O   . ALA B 1 38  ? 126.216 90.831  110.347 1.00 72.87  ? 38  ALA B O   1 
ATOM   3734 C  CB  . ALA B 1 38  ? 125.307 89.221  112.986 1.00 72.87  ? 38  ALA B CB  1 
ATOM   3735 N  N   . ALA B 1 39  ? 127.375 91.528  112.144 1.00 71.74  ? 39  ALA B N   1 
ATOM   3736 C  CA  . ALA B 1 39  ? 128.445 92.104  111.348 1.00 71.74  ? 39  ALA B CA  1 
ATOM   3737 C  C   . ALA B 1 39  ? 129.309 91.055  110.676 1.00 71.74  ? 39  ALA B C   1 
ATOM   3738 O  O   . ALA B 1 39  ? 130.086 91.394  109.785 1.00 71.74  ? 39  ALA B O   1 
ATOM   3739 C  CB  . ALA B 1 39  ? 129.302 92.999  112.225 1.00 71.74  ? 39  ALA B CB  1 
ATOM   3740 N  N   . SER B 1 40  ? 129.193 89.792  111.071 1.00 72.36  ? 40  SER B N   1 
ATOM   3741 C  CA  . SER B 1 40  ? 129.947 88.744  110.403 1.00 72.36  ? 40  SER B CA  1 
ATOM   3742 C  C   . SER B 1 40  ? 129.342 88.366  109.062 1.00 72.36  ? 40  SER B C   1 
ATOM   3743 O  O   . SER B 1 40  ? 129.988 87.666  108.281 1.00 72.36  ? 40  SER B O   1 
ATOM   3744 C  CB  . SER B 1 40  ? 130.043 87.525  111.309 1.00 72.36  ? 40  SER B CB  1 
ATOM   3745 O  OG  . SER B 1 40  ? 128.766 86.982  111.553 1.00 72.36  ? 40  SER B OG  1 
ATOM   3746 N  N   . LEU B 1 41  ? 128.123 88.815  108.778 1.00 73.55  ? 41  LEU B N   1 
ATOM   3747 C  CA  . LEU B 1 41  ? 127.510 88.591  107.480 1.00 73.55  ? 41  LEU B CA  1 
ATOM   3748 C  C   . LEU B 1 41  ? 127.981 89.586  106.436 1.00 73.55  ? 41  LEU B C   1 
ATOM   3749 O  O   . LEU B 1 41  ? 127.634 89.443  105.263 1.00 73.55  ? 41  LEU B O   1 
ATOM   3750 C  CB  . LEU B 1 41  ? 125.997 88.662  107.606 1.00 73.55  ? 41  LEU B CB  1 
ATOM   3751 C  CG  . LEU B 1 41  ? 125.394 87.554  108.448 1.00 73.55  ? 41  LEU B CG  1 
ATOM   3752 C  CD1 . LEU B 1 41  ? 123.984 87.905  108.816 1.00 73.55  ? 41  LEU B CD1 1 
ATOM   3753 C  CD2 . LEU B 1 41  ? 125.437 86.272  107.671 1.00 73.55  ? 41  LEU B CD2 1 
ATOM   3754 N  N   . ILE B 1 42  ? 128.751 90.592  106.837 1.00 72.40  ? 42  ILE B N   1 
ATOM   3755 C  CA  . ILE B 1 42  ? 129.317 91.535  105.889 1.00 72.40  ? 42  ILE B CA  1 
ATOM   3756 C  C   . ILE B 1 42  ? 130.442 90.859  105.122 1.00 72.40  ? 42  ILE B C   1 
ATOM   3757 O  O   . ILE B 1 42  ? 131.350 90.269  105.715 1.00 72.40  ? 42  ILE B O   1 
ATOM   3758 C  CB  . ILE B 1 42  ? 129.811 92.780  106.632 1.00 72.40  ? 42  ILE B CB  1 
ATOM   3759 C  CG1 . ILE B 1 42  ? 128.628 93.595  107.131 1.00 72.40  ? 42  ILE B CG1 1 
ATOM   3760 C  CG2 . ILE B 1 42  ? 130.680 93.602  105.754 1.00 72.40  ? 42  ILE B CG2 1 
ATOM   3761 C  CD1 . ILE B 1 42  ? 128.985 94.560  108.209 1.00 72.40  ? 42  ILE B CD1 1 
ATOM   3762 N  N   . ASP B 1 43  ? 130.388 90.938  103.799 1.00 76.41  ? 43  ASP B N   1 
ATOM   3763 C  CA  . ASP B 1 43  ? 131.404 90.337  102.956 1.00 76.41  ? 43  ASP B CA  1 
ATOM   3764 C  C   . ASP B 1 43  ? 132.339 91.371  102.345 1.00 76.41  ? 43  ASP B C   1 
ATOM   3765 O  O   . ASP B 1 43  ? 133.120 91.037  101.454 1.00 76.41  ? 43  ASP B O   1 
ATOM   3766 C  CB  . ASP B 1 43  ? 130.739 89.500  101.871 1.00 76.41  ? 43  ASP B CB  1 
ATOM   3767 C  CG  . ASP B 1 43  ? 131.565 88.311  101.469 1.00 76.41  ? 43  ASP B CG  1 
ATOM   3768 O  OD1 . ASP B 1 43  ? 131.656 87.363  102.271 1.00 76.41  ? 43  ASP B OD1 1 
ATOM   3769 O  OD2 . ASP B 1 43  ? 132.119 88.311  100.353 1.00 76.41  ? 43  ASP B OD2 1 
ATOM   3770 N  N   . GLY B 1 44  ? 132.281 92.612  102.802 1.00 75.10  ? 44  GLY B N   1 
ATOM   3771 C  CA  . GLY B 1 44  ? 133.235 93.630  102.417 1.00 75.10  ? 44  GLY B CA  1 
ATOM   3772 C  C   . GLY B 1 44  ? 132.581 94.777  101.669 1.00 75.10  ? 44  GLY B C   1 
ATOM   3773 O  O   . GLY B 1 44  ? 131.424 94.722  101.260 1.00 75.10  ? 44  GLY B O   1 
ATOM   3774 N  N   . ILE B 1 45  ? 133.358 95.842  101.504 1.00 72.19  ? 45  ILE B N   1 
ATOM   3775 C  CA  . ILE B 1 45  ? 132.959 96.974  100.678 1.00 72.19  ? 45  ILE B CA  1 
ATOM   3776 C  C   . ILE B 1 45  ? 134.161 97.417  99.853  1.00 72.19  ? 45  ILE B C   1 
ATOM   3777 O  O   . ILE B 1 45  ? 135.269 97.566  100.376 1.00 72.19  ? 45  ILE B O   1 
ATOM   3778 C  CB  . ILE B 1 45  ? 132.363 98.132  101.513 1.00 72.19  ? 45  ILE B CB  1 
ATOM   3779 C  CG1 . ILE B 1 45  ? 131.864 99.254  100.611 1.00 72.19  ? 45  ILE B CG1 1 
ATOM   3780 C  CG2 . ILE B 1 45  ? 133.313 98.688  102.563 1.00 72.19  ? 45  ILE B CG2 1 
ATOM   3781 C  CD1 . ILE B 1 45  ? 131.013 100.246 101.327 1.00 72.19  ? 45  ILE B CD1 1 
ATOM   3782 N  N   . GLY B 1 46  ? 133.961 97.557  98.548  1.00 72.90  ? 46  GLY B N   1 
ATOM   3783 C  CA  . GLY B 1 46  ? 134.997 98.052  97.669  1.00 72.90  ? 46  GLY B CA  1 
ATOM   3784 C  C   . GLY B 1 46  ? 134.706 99.502  97.344  1.00 72.90  ? 46  GLY B C   1 
ATOM   3785 O  O   . GLY B 1 46  ? 133.598 99.842  96.941  1.00 72.90  ? 46  GLY B O   1 
ATOM   3786 N  N   . VAL B 1 47  ? 135.703 100.350 97.537  1.00 73.00  ? 47  VAL B N   1 
ATOM   3787 C  CA  . VAL B 1 47  ? 135.544 101.792 97.429  1.00 73.00  ? 47  VAL B CA  1 
ATOM   3788 C  C   . VAL B 1 47  ? 136.402 102.280 96.277  1.00 73.00  ? 47  VAL B C   1 
ATOM   3789 O  O   . VAL B 1 47  ? 137.580 101.924 96.184  1.00 73.00  ? 47  VAL B O   1 
ATOM   3790 C  CB  . VAL B 1 47  ? 135.931 102.491 98.743  1.00 73.00  ? 47  VAL B CB  1 
ATOM   3791 C  CG1 . VAL B 1 47  ? 135.821 103.982 98.616  1.00 73.00  ? 47  VAL B CG1 1 
ATOM   3792 C  CG2 . VAL B 1 47  ? 135.055 101.998 99.862  1.00 73.00  ? 47  VAL B CG2 1 
ATOM   3793 N  N   . ARG B 1 48  ? 135.815 103.085 95.399  1.00 78.23  ? 48  ARG B N   1 
ATOM   3794 C  CA  . ARG B 1 48  ? 136.544 103.622 94.263  1.00 78.23  ? 48  ARG B CA  1 
ATOM   3795 C  C   . ARG B 1 48  ? 136.171 105.077 94.043  1.00 78.23  ? 48  ARG B C   1 
ATOM   3796 O  O   . ARG B 1 48  ? 134.991 105.408 93.925  1.00 78.23  ? 48  ARG B O   1 
ATOM   3797 C  CB  . ARG B 1 48  ? 136.259 102.805 93.005  1.00 78.23  ? 48  ARG B CB  1 
ATOM   3798 C  CG  . ARG B 1 48  ? 136.575 103.523 91.733  1.00 78.23  ? 48  ARG B CG  1 
ATOM   3799 C  CD  . ARG B 1 48  ? 136.626 102.578 90.561  1.00 78.23  ? 48  ARG B CD  1 
ATOM   3800 N  NE  . ARG B 1 48  ? 136.743 103.308 89.304  1.00 78.23  ? 48  ARG B NE  1 
ATOM   3801 C  CZ  . ARG B 1 48  ? 137.886 103.768 88.806  1.00 78.23  ? 48  ARG B CZ  1 
ATOM   3802 N  NH1 . ARG B 1 48  ? 139.027 103.570 89.452  1.00 78.23  ? 48  ARG B NH1 1 
ATOM   3803 N  NH2 . ARG B 1 48  ? 137.890 104.423 87.654  1.00 78.23  ? 48  ARG B NH2 1 
ATOM   3804 N  N   . ILE B 1 49  ? 137.177 105.940 94.015  1.00 75.66  ? 49  ILE B N   1 
ATOM   3805 C  CA  . ILE B 1 49  ? 137.058 107.306 93.530  1.00 75.66  ? 49  ILE B CA  1 
ATOM   3806 C  C   . ILE B 1 49  ? 138.033 107.434 92.367  1.00 75.66  ? 49  ILE B C   1 
ATOM   3807 O  O   . ILE B 1 49  ? 139.229 107.202 92.549  1.00 75.66  ? 49  ILE B O   1 
ATOM   3808 C  CB  . ILE B 1 49  ? 137.366 108.350 94.614  1.00 75.66  ? 49  ILE B CB  1 
ATOM   3809 C  CG1 . ILE B 1 49  ? 136.396 108.205 95.776  1.00 75.66  ? 49  ILE B CG1 1 
ATOM   3810 C  CG2 . ILE B 1 49  ? 137.281 109.735 94.039  1.00 75.66  ? 49  ILE B CG2 1 
ATOM   3811 C  CD1 . ILE B 1 49  ? 136.631 109.168 96.885  1.00 75.66  ? 49  ILE B CD1 1 
ATOM   3812 N  N   . PRO B 1 50  ? 137.572 107.782 91.164  1.00 78.87  ? 50  PRO B N   1 
ATOM   3813 C  CA  . PRO B 1 50  ? 138.427 107.699 89.970  1.00 78.87  ? 50  PRO B CA  1 
ATOM   3814 C  C   . PRO B 1 50  ? 139.604 108.659 89.987  1.00 78.87  ? 50  PRO B C   1 
ATOM   3815 O  O   . PRO B 1 50  ? 139.440 109.877 90.076  1.00 78.87  ? 50  PRO B O   1 
ATOM   3816 C  CB  . PRO B 1 50  ? 137.459 108.031 88.830  1.00 78.87  ? 50  PRO B CB  1 
ATOM   3817 C  CG  . PRO B 1 50  ? 136.338 108.736 89.474  1.00 78.87  ? 50  PRO B CG  1 
ATOM   3818 C  CD  . PRO B 1 50  ? 136.186 108.108 90.809  1.00 78.87  ? 50  PRO B CD  1 
ATOM   3819 N  N   . GLY B 1 51  ? 140.803 108.089 89.911  1.00 79.67  ? 51  GLY B N   1 
ATOM   3820 C  CA  . GLY B 1 51  ? 142.030 108.843 89.982  1.00 79.67  ? 51  GLY B CA  1 
ATOM   3821 C  C   . GLY B 1 51  ? 142.657 108.924 91.353  1.00 79.67  ? 51  GLY B C   1 
ATOM   3822 O  O   . GLY B 1 51  ? 143.864 109.167 91.447  1.00 79.67  ? 51  GLY B O   1 
ATOM   3823 N  N   . LEU B 1 52  ? 141.889 108.716 92.416  1.00 77.83  ? 52  LEU B N   1 
ATOM   3824 C  CA  . LEU B 1 52  ? 142.387 108.894 93.771  1.00 77.83  ? 52  LEU B CA  1 
ATOM   3825 C  C   . LEU B 1 52  ? 142.408 107.603 94.571  1.00 77.83  ? 52  LEU B C   1 
ATOM   3826 O  O   . LEU B 1 52  ? 143.442 107.258 95.149  1.00 77.83  ? 52  LEU B O   1 
ATOM   3827 C  CB  . LEU B 1 52  ? 141.539 109.945 94.497  1.00 77.83  ? 52  LEU B CB  1 
ATOM   3828 C  CG  . LEU B 1 52  ? 141.544 111.343 93.887  1.00 77.83  ? 52  LEU B CG  1 
ATOM   3829 C  CD1 . LEU B 1 52  ? 140.610 112.243 94.649  1.00 77.83  ? 52  LEU B CD1 1 
ATOM   3830 C  CD2 . LEU B 1 52  ? 142.937 111.914 93.888  1.00 77.83  ? 52  LEU B CD2 1 
ATOM   3831 N  N   . VAL B 1 53  ? 141.288 106.888 94.644  1.00 77.27  ? 53  VAL B N   1 
ATOM   3832 C  CA  . VAL B 1 53  ? 141.152 105.717 95.501  1.00 77.27  ? 53  VAL B CA  1 
ATOM   3833 C  C   . VAL B 1 53  ? 140.644 104.557 94.661  1.00 77.27  ? 53  VAL B C   1 
ATOM   3834 O  O   . VAL B 1 53  ? 139.708 104.705 93.875  1.00 77.27  ? 53  VAL B O   1 
ATOM   3835 C  CB  . VAL B 1 53  ? 140.175 105.970 96.676  1.00 77.27  ? 53  VAL B CB  1 
ATOM   3836 C  CG1 . VAL B 1 53  ? 140.165 104.807 97.633  1.00 77.27  ? 53  VAL B CG1 1 
ATOM   3837 C  CG2 . VAL B 1 53  ? 140.497 107.242 97.413  1.00 77.27  ? 53  VAL B CG2 1 
ATOM   3838 N  N   . ASP B 1 54  ? 141.261 103.389 94.833  1.00 81.60  ? 54  ASP B N   1 
ATOM   3839 C  CA  . ASP B 1 54  ? 140.678 102.150 94.313  1.00 81.60  ? 54  ASP B CA  1 
ATOM   3840 C  C   . ASP B 1 54  ? 141.153 101.018 95.225  1.00 81.60  ? 54  ASP B C   1 
ATOM   3841 O  O   . ASP B 1 54  ? 142.258 100.503 95.053  1.00 81.60  ? 54  ASP B O   1 
ATOM   3842 C  CB  . ASP B 1 54  ? 141.075 101.903 92.871  1.00 81.60  ? 54  ASP B CB  1 
ATOM   3843 C  CG  . ASP B 1 54  ? 140.121 100.971 92.154  1.00 81.60  ? 54  ASP B CG  1 
ATOM   3844 O  OD1 . ASP B 1 54  ? 139.371 100.236 92.825  1.00 81.60  ? 54  ASP B OD1 1 
ATOM   3845 O  OD2 . ASP B 1 54  ? 140.113 100.976 90.905  1.00 81.60  ? 54  ASP B OD2 1 
ATOM   3846 N  N   . VAL B 1 55  ? 140.309 100.640 96.182  1.00 76.21  ? 55  VAL B N   1 
ATOM   3847 C  CA  . VAL B 1 55  ? 140.652 99.605  97.144  1.00 76.21  ? 55  VAL B CA  1 
ATOM   3848 C  C   . VAL B 1 55  ? 139.699 98.433  96.976  1.00 76.21  ? 55  VAL B C   1 
ATOM   3849 O  O   . VAL B 1 55  ? 138.599 98.560  96.437  1.00 76.21  ? 55  VAL B O   1 
ATOM   3850 C  CB  . VAL B 1 55  ? 140.633 100.113 98.599  1.00 76.21  ? 55  VAL B CB  1 
ATOM   3851 C  CG1 . VAL B 1 55  ? 141.628 101.226 98.769  1.00 76.21  ? 55  VAL B CG1 1 
ATOM   3852 C  CG2 . VAL B 1 55  ? 139.253 100.577 98.986  1.00 76.21  ? 55  VAL B CG2 1 
ATOM   3853 N  N   . GLY B 1 56  ? 140.150 97.279  97.436  1.00 78.16  ? 56  GLY B N   1 
ATOM   3854 C  CA  . GLY B 1 56  ? 139.375 96.068  97.345  1.00 78.16  ? 56  GLY B CA  1 
ATOM   3855 C  C   . GLY B 1 56  ? 138.347 95.977  98.444  1.00 78.16  ? 56  GLY B C   1 
ATOM   3856 O  O   . GLY B 1 56  ? 138.193 96.872  99.280  1.00 78.16  ? 56  GLY B O   1 
ATOM   3857 N  N   . PRO B 1 57  ? 137.609 94.868  98.454  1.00 77.37  ? 57  PRO B N   1 
ATOM   3858 C  CA  . PRO B 1 57  ? 136.541 94.724  99.450  1.00 77.37  ? 57  PRO B CA  1 
ATOM   3859 C  C   . PRO B 1 57  ? 137.036 94.463  100.859 1.00 77.37  ? 57  PRO B C   1 
ATOM   3860 O  O   . PRO B 1 57  ? 136.282 94.678  101.812 1.00 77.37  ? 57  PRO B O   1 
ATOM   3861 C  CB  . PRO B 1 57  ? 135.717 93.549  98.910  1.00 77.37  ? 57  PRO B CB  1 
ATOM   3862 C  CG  . PRO B 1 57  ? 136.637 92.811  98.045  1.00 77.37  ? 57  PRO B CG  1 
ATOM   3863 C  CD  . PRO B 1 57  ? 137.560 93.806  97.441  1.00 77.37  ? 57  PRO B CD  1 
ATOM   3864 N  N   . ASP B 1 58  ? 138.276 94.030  101.036 1.00 76.75  ? 58  ASP B N   1 
ATOM   3865 C  CA  . ASP B 1 58  ? 138.770 93.684  102.360 1.00 76.75  ? 58  ASP B CA  1 
ATOM   3866 C  C   . ASP B 1 58  ? 139.678 94.745  102.964 1.00 76.75  ? 58  ASP B C   1 
ATOM   3867 O  O   . ASP B 1 58  ? 140.182 94.547  104.071 1.00 76.75  ? 58  ASP B O   1 
ATOM   3868 C  CB  . ASP B 1 58  ? 139.512 92.354  102.304 1.00 76.75  ? 58  ASP B CB  1 
ATOM   3869 C  CG  . ASP B 1 58  ? 140.745 92.423  101.447 1.00 76.75  ? 58  ASP B CG  1 
ATOM   3870 O  OD1 . ASP B 1 58  ? 141.856 92.304  102.000 1.00 76.75  ? 58  ASP B OD1 1 
ATOM   3871 O  OD2 . ASP B 1 58  ? 140.608 92.602  100.221 1.00 76.75  ? 58  ASP B OD2 1 
ATOM   3872 N  N   . VAL B 1 59  ? 139.904 95.851  102.270 1.00 74.43  ? 59  VAL B N   1 
ATOM   3873 C  CA  . VAL B 1 59  ? 140.792 96.916  102.734 1.00 74.43  ? 59  VAL B CA  1 
ATOM   3874 C  C   . VAL B 1 59  ? 140.153 97.869  103.752 1.00 74.43  ? 59  VAL B C   1 
ATOM   3875 O  O   . VAL B 1 59  ? 140.805 98.137  104.771 1.00 74.43  ? 59  VAL B O   1 
ATOM   3876 C  CB  . VAL B 1 59  ? 141.380 97.674  101.530 1.00 74.43  ? 59  VAL B CB  1 
ATOM   3877 C  CG1 . VAL B 1 59  ? 142.306 98.782  101.973 1.00 74.43  ? 59  VAL B CG1 1 
ATOM   3878 C  CG2 . VAL B 1 59  ? 142.112 96.711  100.627 1.00 74.43  ? 59  VAL B CG2 1 
ATOM   3879 N  N   . PRO B 1 60  ? 138.934 98.413  103.579 1.00 71.39  ? 60  PRO B N   1 
ATOM   3880 C  CA  . PRO B 1 60  ? 138.448 99.384  104.567 1.00 71.39  ? 60  PRO B CA  1 
ATOM   3881 C  C   . PRO B 1 60  ? 138.080 98.777  105.912 1.00 71.39  ? 60  PRO B C   1 
ATOM   3882 O  O   . PRO B 1 60  ? 137.890 97.569  106.051 1.00 71.39  ? 60  PRO B O   1 
ATOM   3883 C  CB  . PRO B 1 60  ? 137.211 99.980  103.890 1.00 71.39  ? 60  PRO B CB  1 
ATOM   3884 C  CG  . PRO B 1 60  ? 137.409 99.736  102.485 1.00 71.39  ? 60  PRO B CG  1 
ATOM   3885 C  CD  . PRO B 1 60  ? 137.984 98.391  102.448 1.00 71.39  ? 60  PRO B CD  1 
ATOM   3886 N  N   . LEU B 1 61  ? 137.987 99.647  106.912 1.00 69.00  ? 61  LEU B N   1 
ATOM   3887 C  CA  . LEU B 1 61  ? 137.661 99.270  108.277 1.00 69.00  ? 61  LEU B CA  1 
ATOM   3888 C  C   . LEU B 1 61  ? 136.263 99.747  108.633 1.00 69.00  ? 61  LEU B C   1 
ATOM   3889 O  O   . LEU B 1 61  ? 135.785 100.757 108.116 1.00 69.00  ? 61  LEU B O   1 
ATOM   3890 C  CB  . LEU B 1 61  ? 138.663 99.855  109.267 1.00 69.00  ? 61  LEU B CB  1 
ATOM   3891 C  CG  . LEU B 1 61  ? 140.140 99.737  108.922 1.00 69.00  ? 61  LEU B CG  1 
ATOM   3892 C  CD1 . LEU B 1 61  ? 140.960 100.363 110.008 1.00 69.00  ? 61  LEU B CD1 1 
ATOM   3893 C  CD2 . LEU B 1 61  ? 140.524 98.301  108.750 1.00 69.00  ? 61  LEU B CD2 1 
ATOM   3894 N  N   . TRP B 1 62  ? 135.620 99.025  109.540 1.00 67.99  ? 62  TRP B N   1 
ATOM   3895 C  CA  . TRP B 1 62  ? 134.210 99.201  109.842 1.00 67.99  ? 62  TRP B CA  1 
ATOM   3896 C  C   . TRP B 1 62  ? 134.044 99.650  111.281 1.00 67.99  ? 62  TRP B C   1 
ATOM   3897 O  O   . TRP B 1 62  ? 134.536 98.988  112.194 1.00 67.99  ? 62  TRP B O   1 
ATOM   3898 C  CB  . TRP B 1 62  ? 133.450 97.897  109.622 1.00 67.99  ? 62  TRP B CB  1 
ATOM   3899 C  CG  . TRP B 1 62  ? 133.342 97.500  108.206 1.00 67.99  ? 62  TRP B CG  1 
ATOM   3900 C  CD1 . TRP B 1 62  ? 134.337 97.056  107.400 1.00 67.99  ? 62  TRP B CD1 1 
ATOM   3901 C  CD2 . TRP B 1 62  ? 132.159 97.504  107.419 1.00 67.99  ? 62  TRP B CD2 1 
ATOM   3902 N  NE1 . TRP B 1 62  ? 133.851 96.790  106.153 1.00 67.99  ? 62  TRP B NE1 1 
ATOM   3903 C  CE2 . TRP B 1 62  ? 132.510 97.056  106.140 1.00 67.99  ? 62  TRP B CE2 1 
ATOM   3904 C  CE3 . TRP B 1 62  ? 130.830 97.841  107.673 1.00 67.99  ? 62  TRP B CE3 1 
ATOM   3905 C  CZ2 . TRP B 1 62  ? 131.587 96.947  105.119 1.00 67.99  ? 62  TRP B CZ2 1 
ATOM   3906 C  CZ3 . TRP B 1 62  ? 129.919 97.734  106.657 1.00 67.99  ? 62  TRP B CZ3 1 
ATOM   3907 C  CH2 . TRP B 1 62  ? 130.298 97.286  105.396 1.00 67.99  ? 62  TRP B CH2 1 
ATOM   3908 N  N   . THR B 1 63  ? 133.341 100.754 111.485 1.00 69.51  ? 63  THR B N   1 
ATOM   3909 C  CA  . THR B 1 63  ? 133.008 101.232 112.820 1.00 69.51  ? 63  THR B CA  1 
ATOM   3910 C  C   . THR B 1 63  ? 131.545 100.921 113.084 1.00 69.51  ? 63  THR B C   1 
ATOM   3911 O  O   . THR B 1 63  ? 130.658 101.610 112.579 1.00 69.51  ? 63  THR B O   1 
ATOM   3912 C  CB  . THR B 1 63  ? 133.272 102.723 112.964 1.00 69.51  ? 63  THR B CB  1 
ATOM   3913 O  OG1 . THR B 1 63  ? 134.591 103.022 112.503 1.00 69.51  ? 63  THR B OG1 1 
ATOM   3914 C  CG2 . THR B 1 63  ? 133.147 103.130 114.405 1.00 69.51  ? 63  THR B CG2 1 
ATOM   3915 N  N   . LEU B 1 64  ? 131.295 99.885  113.872 1.00 71.28  ? 64  LEU B N   1 
ATOM   3916 C  CA  . LEU B 1 64  ? 129.949 99.434  114.179 1.00 71.28  ? 64  LEU B CA  1 
ATOM   3917 C  C   . LEU B 1 64  ? 129.757 99.439  115.683 1.00 71.28  ? 64  LEU B C   1 
ATOM   3918 O  O   . LEU B 1 64  ? 130.531 98.807  116.407 1.00 71.28  ? 64  LEU B O   1 
ATOM   3919 C  CB  . LEU B 1 64  ? 129.698 98.042  113.616 1.00 71.28  ? 64  LEU B CB  1 
ATOM   3920 C  CG  . LEU B 1 64  ? 129.744 98.005  112.098 1.00 71.28  ? 64  LEU B CG  1 
ATOM   3921 C  CD1 . LEU B 1 64  ? 129.881 96.604  111.618 1.00 71.28  ? 64  LEU B CD1 1 
ATOM   3922 C  CD2 . LEU B 1 64  ? 128.502 98.632  111.543 1.00 71.28  ? 64  LEU B CD2 1 
ATOM   3923 N  N   . GLN B 1 65  ? 128.732 100.169 116.131 1.00 73.56  ? 65  GLN B N   1 
ATOM   3924 C  CA  . GLN B 1 65  ? 128.366 100.319 117.541 1.00 73.56  ? 65  GLN B CA  1 
ATOM   3925 C  C   . GLN B 1 65  ? 129.517 100.866 118.381 1.00 73.56  ? 65  GLN B C   1 
ATOM   3926 O  O   . GLN B 1 65  ? 129.780 100.394 119.485 1.00 73.56  ? 65  GLN B O   1 
ATOM   3927 C  CB  . GLN B 1 65  ? 127.839 99.008  118.121 1.00 73.56  ? 65  GLN B CB  1 
ATOM   3928 C  CG  . GLN B 1 65  ? 126.569 98.535  117.473 1.00 73.56  ? 65  GLN B CG  1 
ATOM   3929 C  CD  . GLN B 1 65  ? 126.212 97.138  117.884 1.00 73.56  ? 65  GLN B CD  1 
ATOM   3930 O  OE1 . GLN B 1 65  ? 127.080 96.288  118.028 1.00 73.56  ? 65  GLN B OE1 1 
ATOM   3931 N  NE2 . GLN B 1 65  ? 124.930 96.890  118.083 1.00 73.56  ? 65  GLN B NE2 1 
ATOM   3932 N  N   . GLY B 1 66  ? 130.213 101.864 117.847 1.00 76.08  ? 66  GLY B N   1 
ATOM   3933 C  CA  . GLY B 1 66  ? 131.223 102.577 118.597 1.00 76.08  ? 66  GLY B CA  1 
ATOM   3934 C  C   . GLY B 1 66  ? 132.583 101.929 118.661 1.00 76.08  ? 66  GLY B C   1 
ATOM   3935 O  O   . GLY B 1 66  ? 133.404 102.340 119.485 1.00 76.08  ? 66  GLY B O   1 
ATOM   3936 N  N   . GLN B 1 67  ? 132.856 100.936 117.826 1.00 76.50  ? 67  GLN B N   1 
ATOM   3937 C  CA  . GLN B 1 67  ? 134.113 100.209 117.861 1.00 76.50  ? 67  GLN B CA  1 
ATOM   3938 C  C   . GLN B 1 67  ? 134.537 99.882  116.440 1.00 76.50  ? 67  GLN B C   1 
ATOM   3939 O  O   . GLN B 1 67  ? 133.715 99.456  115.630 1.00 76.50  ? 67  GLN B O   1 
ATOM   3940 C  CB  . GLN B 1 67  ? 133.966 98.935  118.681 1.00 76.50  ? 67  GLN B CB  1 
ATOM   3941 C  CG  . GLN B 1 67  ? 135.240 98.166  118.884 1.00 76.50  ? 67  GLN B CG  1 
ATOM   3942 C  CD  . GLN B 1 67  ? 136.227 98.913  119.724 1.00 76.50  ? 67  GLN B CD  1 
ATOM   3943 O  OE1 . GLN B 1 67  ? 137.231 99.417  119.223 1.00 76.50  ? 67  GLN B OE1 1 
ATOM   3944 N  NE2 . GLN B 1 67  ? 135.950 99.002  121.016 1.00 76.50  ? 67  GLN B NE2 1 
ATOM   3945 N  N   . GLN B 1 68  ? 135.814 100.076 116.138 1.00 72.55  ? 68  GLN B N   1 
ATOM   3946 C  CA  . GLN B 1 68  ? 136.319 99.891  114.786 1.00 72.55  ? 68  GLN B CA  1 
ATOM   3947 C  C   . GLN B 1 68  ? 136.920 98.505  114.619 1.00 72.55  ? 68  GLN B C   1 
ATOM   3948 O  O   . GLN B 1 68  ? 137.643 98.022  115.493 1.00 72.55  ? 68  GLN B O   1 
ATOM   3949 C  CB  . GLN B 1 68  ? 137.362 100.946 114.436 1.00 72.55  ? 68  GLN B CB  1 
ATOM   3950 C  CG  . GLN B 1 68  ? 137.655 101.014 112.963 1.00 72.55  ? 68  GLN B CG  1 
ATOM   3951 C  CD  . GLN B 1 68  ? 138.667 102.061 112.621 1.00 72.55  ? 68  GLN B CD  1 
ATOM   3952 O  OE1 . GLN B 1 68  ? 139.813 101.992 113.050 1.00 72.55  ? 68  GLN B OE1 1 
ATOM   3953 N  NE2 . GLN B 1 68  ? 138.257 103.041 111.835 1.00 72.55  ? 68  GLN B NE2 1 
ATOM   3954 N  N   . TYR B 1 69  ? 136.625 97.875  113.485 1.00 72.73  ? 69  TYR B N   1 
ATOM   3955 C  CA  . TYR B 1 69  ? 137.084 96.528  113.197 1.00 72.73  ? 69  TYR B CA  1 
ATOM   3956 C  C   . TYR B 1 69  ? 137.615 96.445  111.778 1.00 72.73  ? 69  TYR B C   1 
ATOM   3957 O  O   . TYR B 1 69  ? 137.228 97.216  110.902 1.00 72.73  ? 69  TYR B O   1 
ATOM   3958 C  CB  . TYR B 1 69  ? 135.966 95.500  113.344 1.00 72.73  ? 69  TYR B CB  1 
ATOM   3959 C  CG  . TYR B 1 69  ? 135.264 95.498  114.667 1.00 72.73  ? 69  TYR B CG  1 
ATOM   3960 C  CD1 . TYR B 1 69  ? 135.715 94.706  115.705 1.00 72.73  ? 69  TYR B CD1 1 
ATOM   3961 C  CD2 . TYR B 1 69  ? 134.135 96.269  114.872 1.00 72.73  ? 69  TYR B CD2 1 
ATOM   3962 C  CE1 . TYR B 1 69  ? 135.075 94.695  116.908 1.00 72.73  ? 69  TYR B CE1 1 
ATOM   3963 C  CE2 . TYR B 1 69  ? 133.490 96.263  116.073 1.00 72.73  ? 69  TYR B CE2 1 
ATOM   3964 C  CZ  . TYR B 1 69  ? 133.962 95.472  117.084 1.00 72.73  ? 69  TYR B CZ  1 
ATOM   3965 O  OH  . TYR B 1 69  ? 133.316 95.467  118.290 1.00 72.73  ? 69  TYR B OH  1 
ATOM   3966 N  N   . THR B 1 70  ? 138.506 95.486  111.561 1.00 73.78  ? 70  THR B N   1 
ATOM   3967 C  CA  . THR B 1 70  ? 138.832 95.067  110.213 1.00 73.78  ? 70  THR B CA  1 
ATOM   3968 C  C   . THR B 1 70  ? 137.818 94.030  109.750 1.00 73.78  ? 70  THR B C   1 
ATOM   3969 O  O   . THR B 1 70  ? 136.967 93.579  110.514 1.00 73.78  ? 70  THR B O   1 
ATOM   3970 C  CB  . THR B 1 70  ? 140.241 94.494  110.148 1.00 73.78  ? 70  THR B CB  1 
ATOM   3971 O  OG1 . THR B 1 70  ? 140.229 93.160  110.654 1.00 73.78  ? 70  THR B OG1 1 
ATOM   3972 C  CG2 . THR B 1 70  ? 141.178 95.314  110.982 1.00 73.78  ? 70  THR B CG2 1 
ATOM   3973 N  N   . LEU B 1 71  ? 137.907 93.649  108.477 1.00 74.30  ? 71  LEU B N   1 
ATOM   3974 C  CA  . LEU B 1 71  ? 136.955 92.682  107.945 1.00 74.30  ? 71  LEU B CA  1 
ATOM   3975 C  C   . LEU B 1 71  ? 137.221 91.290  108.494 1.00 74.30  ? 71  LEU B C   1 
ATOM   3976 O  O   . LEU B 1 71  ? 136.285 90.518  108.719 1.00 74.30  ? 71  LEU B O   1 
ATOM   3977 C  CB  . LEU B 1 71  ? 137.002 92.673  106.421 1.00 74.30  ? 71  LEU B CB  1 
ATOM   3978 C  CG  . LEU B 1 71  ? 135.917 91.839  105.745 1.00 74.30  ? 71  LEU B CG  1 
ATOM   3979 C  CD1 . LEU B 1 71  ? 134.557 92.403  106.051 1.00 74.30  ? 71  LEU B CD1 1 
ATOM   3980 C  CD2 . LEU B 1 71  ? 136.139 91.761  104.262 1.00 74.30  ? 71  LEU B CD2 1 
ATOM   3981 N  N   . ALA B 1 72  ? 138.487 90.960  108.743 1.00 75.31  ? 72  ALA B N   1 
ATOM   3982 C  CA  . ALA B 1 72  ? 138.807 89.660  109.319 1.00 75.31  ? 72  ALA B CA  1 
ATOM   3983 C  C   . ALA B 1 72  ? 138.374 89.579  110.775 1.00 75.31  ? 72  ALA B C   1 
ATOM   3984 O  O   . ALA B 1 72  ? 138.010 88.506  111.260 1.00 75.31  ? 72  ALA B O   1 
ATOM   3985 C  CB  . ALA B 1 72  ? 140.300 89.381  109.189 1.00 75.31  ? 72  ALA B CB  1 
ATOM   3986 N  N   . GLU B 1 73  ? 138.403 90.705  111.486 1.00 76.89  ? 73  GLU B N   1 
ATOM   3987 C  CA  . GLU B 1 73  ? 137.906 90.724  112.856 1.00 76.89  ? 73  GLU B CA  1 
ATOM   3988 C  C   . GLU B 1 73  ? 136.393 90.620  112.890 1.00 76.89  ? 73  GLU B C   1 
ATOM   3989 O  O   . GLU B 1 73  ? 135.822 90.103  113.854 1.00 76.89  ? 73  GLU B O   1 
ATOM   3990 C  CB  . GLU B 1 73  ? 138.350 91.997  113.563 1.00 76.89  ? 73  GLU B CB  1 
ATOM   3991 C  CG  . GLU B 1 73  ? 139.792 92.020  113.971 1.00 76.89  ? 73  GLU B CG  1 
ATOM   3992 C  CD  . GLU B 1 73  ? 140.191 93.352  114.553 1.00 76.89  ? 73  GLU B CD  1 
ATOM   3993 O  OE1 . GLU B 1 73  ? 139.445 94.332  114.357 1.00 76.89  ? 73  GLU B OE1 1 
ATOM   3994 O  OE2 . GLU B 1 73  ? 141.249 93.422  115.209 1.00 76.89  ? 73  GLU B OE2 1 
ATOM   3995 N  N   . LEU B 1 74  ? 135.726 91.134  111.858 1.00 74.22  ? 74  LEU B N   1 
ATOM   3996 C  CA  . LEU B 1 74  ? 134.278 91.012  111.777 1.00 74.22  ? 74  LEU B CA  1 
ATOM   3997 C  C   . LEU B 1 74  ? 133.866 89.576  111.513 1.00 74.22  ? 74  LEU B C   1 
ATOM   3998 O  O   . LEU B 1 74  ? 132.837 89.120  112.015 1.00 74.22  ? 74  LEU B O   1 
ATOM   3999 C  CB  . LEU B 1 74  ? 133.733 91.920  110.682 1.00 74.22  ? 74  LEU B CB  1 
ATOM   4000 C  CG  . LEU B 1 74  ? 133.651 93.413  110.962 1.00 74.22  ? 74  LEU B CG  1 
ATOM   4001 C  CD1 . LEU B 1 74  ? 132.922 94.096  109.843 1.00 74.22  ? 74  LEU B CD1 1 
ATOM   4002 C  CD2 . LEU B 1 74  ? 132.956 93.657  112.263 1.00 74.22  ? 74  LEU B CD2 1 
ATOM   4003 N  N   . TRP B 1 75  ? 134.665 88.847  110.734 1.00 75.59  ? 75  TRP B N   1 
ATOM   4004 C  CA  . TRP B 1 75  ? 134.305 87.488  110.351 1.00 75.59  ? 75  TRP B CA  1 
ATOM   4005 C  C   . TRP B 1 75  ? 134.389 86.534  111.531 1.00 75.59  ? 75  TRP B C   1 
ATOM   4006 O  O   . TRP B 1 75  ? 133.644 85.552  111.597 1.00 75.59  ? 75  TRP B O   1 
ATOM   4007 C  CB  . TRP B 1 75  ? 135.211 87.013  109.224 1.00 75.59  ? 75  TRP B CB  1 
ATOM   4008 C  CG  . TRP B 1 75  ? 134.789 87.497  107.904 1.00 75.59  ? 75  TRP B CG  1 
ATOM   4009 C  CD1 . TRP B 1 75  ? 133.594 88.042  107.584 1.00 75.59  ? 75  TRP B CD1 1 
ATOM   4010 C  CD2 . TRP B 1 75  ? 135.559 87.483  106.706 1.00 75.59  ? 75  TRP B CD2 1 
ATOM   4011 N  NE1 . TRP B 1 75  ? 133.564 88.373  106.257 1.00 75.59  ? 75  TRP B NE1 1 
ATOM   4012 C  CE2 . TRP B 1 75  ? 134.764 88.037  105.695 1.00 75.59  ? 75  TRP B CE2 1 
ATOM   4013 C  CE3 . TRP B 1 75  ? 136.847 87.059  106.392 1.00 75.59  ? 75  TRP B CE3 1 
ATOM   4014 C  CZ2 . TRP B 1 75  ? 135.212 88.175  104.393 1.00 75.59  ? 75  TRP B CZ2 1 
ATOM   4015 C  CZ3 . TRP B 1 75  ? 137.287 87.193  105.104 1.00 75.59  ? 75  TRP B CZ3 1 
ATOM   4016 C  CH2 . TRP B 1 75  ? 136.476 87.746  104.118 1.00 75.59  ? 75  TRP B CH2 1 
ATOM   4017 N  N   . ASP B 1 76  ? 135.284 86.803  112.471 1.00 80.75  ? 76  ASP B N   1 
ATOM   4018 C  CA  . ASP B 1 76  ? 135.418 85.980  113.661 1.00 80.75  ? 76  ASP B CA  1 
ATOM   4019 C  C   . ASP B 1 76  ? 134.668 86.541  114.857 1.00 80.75  ? 76  ASP B C   1 
ATOM   4020 O  O   . ASP B 1 76  ? 134.640 85.897  115.907 1.00 80.75  ? 76  ASP B O   1 
ATOM   4021 C  CB  . ASP B 1 76  ? 136.891 85.815  114.019 1.00 80.75  ? 76  ASP B CB  1 
ATOM   4022 C  CG  . ASP B 1 76  ? 137.708 85.289  112.869 1.00 80.75  ? 76  ASP B CG  1 
ATOM   4023 O  OD1 . ASP B 1 76  ? 137.120 84.981  111.815 1.00 80.75  ? 76  ASP B OD1 1 
ATOM   4024 O  OD2 . ASP B 1 76  ? 138.940 85.178  113.015 1.00 80.75  ? 76  ASP B OD2 1 
ATOM   4025 N  N   . GLY B 1 77  ? 134.065 87.714  114.727 1.00 82.30  ? 77  GLY B N   1 
ATOM   4026 C  CA  . GLY B 1 77  ? 133.456 88.357  115.868 1.00 82.30  ? 77  GLY B CA  1 
ATOM   4027 C  C   . GLY B 1 77  ? 132.106 87.772  116.225 1.00 82.30  ? 77  GLY B C   1 
ATOM   4028 O  O   . GLY B 1 77  ? 131.486 87.037  115.462 1.00 82.30  ? 77  GLY B O   1 
ATOM   4029 N  N   . ASP B 1 78  ? 131.648 88.120  117.424 1.00 85.50  ? 78  ASP B N   1 
ATOM   4030 C  CA  . ASP B 1 78  ? 130.345 87.718  117.928 1.00 85.50  ? 78  ASP B CA  1 
ATOM   4031 C  C   . ASP B 1 78  ? 129.693 88.900  118.618 1.00 85.50  ? 78  ASP B C   1 
ATOM   4032 O  O   . ASP B 1 78  ? 130.366 89.673  119.302 1.00 85.50  ? 78  ASP B O   1 
ATOM   4033 C  CB  . ASP B 1 78  ? 130.467 86.550  118.903 1.00 85.50  ? 78  ASP B CB  1 
ATOM   4034 C  CG  . ASP B 1 78  ? 130.735 85.241  118.206 1.00 85.50  ? 78  ASP B CG  1 
ATOM   4035 O  OD1 . ASP B 1 78  ? 130.196 85.041  117.102 1.00 85.50  ? 78  ASP B OD1 1 
ATOM   4036 O  OD2 . ASP B 1 78  ? 131.498 84.418  118.750 1.00 85.50  ? 78  ASP B OD2 1 
ATOM   4037 N  N   . GLY B 1 79  ? 128.388 89.042  118.430 1.00 79.92  ? 79  GLY B N   1 
ATOM   4038 C  CA  . GLY B 1 79  ? 127.633 90.063  119.116 1.00 79.92  ? 79  GLY B CA  1 
ATOM   4039 C  C   . GLY B 1 79  ? 127.632 91.428  118.472 1.00 79.92  ? 79  GLY B C   1 
ATOM   4040 O  O   . GLY B 1 79  ? 126.763 92.240  118.802 1.00 79.92  ? 79  GLY B O   1 
ATOM   4041 N  N   . VAL B 1 80  ? 128.558 91.714  117.575 1.00 74.04  ? 80  VAL B N   1 
ATOM   4042 C  CA  . VAL B 1 80  ? 128.607 93.002  116.900 1.00 74.04  ? 80  VAL B CA  1 
ATOM   4043 C  C   . VAL B 1 80  ? 127.575 93.000  115.788 1.00 74.04  ? 80  VAL B C   1 
ATOM   4044 O  O   . VAL B 1 80  ? 127.454 92.025  115.042 1.00 74.04  ? 80  VAL B O   1 
ATOM   4045 C  CB  . VAL B 1 80  ? 130.012 93.284  116.350 1.00 74.04  ? 80  VAL B CB  1 
ATOM   4046 C  CG1 . VAL B 1 80  ? 130.143 94.736  115.959 1.00 74.04  ? 80  VAL B CG1 1 
ATOM   4047 C  CG2 . VAL B 1 80  ? 131.052 92.914  117.372 1.00 74.04  ? 80  VAL B CG2 1 
ATOM   4048 N  N   . ARG B 1 81  ? 126.825 94.087  115.678 1.00 72.33  ? 81  ARG B N   1 
ATOM   4049 C  CA  . ARG B 1 81  ? 125.761 94.198  114.698 1.00 72.33  ? 81  ARG B CA  1 
ATOM   4050 C  C   . ARG B 1 81  ? 125.891 95.495  113.921 1.00 72.33  ? 81  ARG B C   1 
ATOM   4051 O  O   . ARG B 1 81  ? 126.483 96.468  114.384 1.00 72.33  ? 81  ARG B O   1 
ATOM   4052 C  CB  . ARG B 1 81  ? 124.386 94.140  115.360 1.00 72.33  ? 81  ARG B CB  1 
ATOM   4053 C  CG  . ARG B 1 81  ? 124.073 92.816  116.003 1.00 72.33  ? 81  ARG B CG  1 
ATOM   4054 C  CD  . ARG B 1 81  ? 122.621 92.705  116.386 1.00 72.33  ? 81  ARG B CD  1 
ATOM   4055 N  NE  . ARG B 1 81  ? 121.747 92.681  115.224 1.00 72.33  ? 81  ARG B NE  1 
ATOM   4056 C  CZ  . ARG B 1 81  ? 120.979 93.698  114.868 1.00 72.33  ? 81  ARG B CZ  1 
ATOM   4057 N  NH1 . ARG B 1 81  ? 120.993 94.815  115.576 1.00 72.33  ? 81  ARG B NH1 1 
ATOM   4058 N  NH2 . ARG B 1 81  ? 120.214 93.612  113.802 1.00 72.33  ? 81  ARG B NH2 1 
ATOM   4059 N  N   . TRP B 1 82  ? 125.339 95.481  112.716 1.00 70.15  ? 82  TRP B N   1 
ATOM   4060 C  CA  . TRP B 1 82  ? 125.055 96.684  111.948 1.00 70.15  ? 82  TRP B CA  1 
ATOM   4061 C  C   . TRP B 1 82  ? 123.562 96.924  112.094 1.00 70.15  ? 82  TRP B C   1 
ATOM   4062 O  O   . TRP B 1 82  ? 122.766 96.289  111.399 1.00 70.15  ? 82  TRP B O   1 
ATOM   4063 C  CB  . TRP B 1 82  ? 125.456 96.508  110.481 1.00 70.15  ? 82  TRP B CB  1 
ATOM   4064 C  CG  . TRP B 1 82  ? 125.294 97.710  109.576 1.00 70.15  ? 82  TRP B CG  1 
ATOM   4065 C  CD1 . TRP B 1 82  ? 124.810 98.940  109.904 1.00 70.15  ? 82  TRP B CD1 1 
ATOM   4066 C  CD2 . TRP B 1 82  ? 125.624 97.775  108.188 1.00 70.15  ? 82  TRP B CD2 1 
ATOM   4067 N  NE1 . TRP B 1 82  ? 124.811 99.757  108.812 1.00 70.15  ? 82  TRP B NE1 1 
ATOM   4068 C  CE2 . TRP B 1 82  ? 125.309 99.065  107.744 1.00 70.15  ? 82  TRP B CE2 1 
ATOM   4069 C  CE3 . TRP B 1 82  ? 126.158 96.865  107.279 1.00 70.15  ? 82  TRP B CE3 1 
ATOM   4070 C  CZ2 . TRP B 1 82  ? 125.511 99.468  106.434 1.00 70.15  ? 82  TRP B CZ2 1 
ATOM   4071 C  CZ3 . TRP B 1 82  ? 126.352 97.265  105.984 1.00 70.15  ? 82  TRP B CZ3 1 
ATOM   4072 C  CH2 . TRP B 1 82  ? 126.032 98.554  105.572 1.00 70.15  ? 82  TRP B CH2 1 
ATOM   4073 N  N   . PRO B 1 83  ? 123.137 97.806  112.991 1.00 71.68  ? 83  PRO B N   1 
ATOM   4074 C  CA  . PRO B 1 83  ? 121.706 98.046  113.168 1.00 71.68  ? 83  PRO B CA  1 
ATOM   4075 C  C   . PRO B 1 83  ? 121.128 98.833  112.010 1.00 71.68  ? 83  PRO B C   1 
ATOM   4076 O  O   . PRO B 1 83  ? 121.832 99.569  111.320 1.00 71.68  ? 83  PRO B O   1 
ATOM   4077 C  CB  . PRO B 1 83  ? 121.643 98.854  114.467 1.00 71.68  ? 83  PRO B CB  1 
ATOM   4078 C  CG  . PRO B 1 83  ? 122.967 98.674  115.099 1.00 71.68  ? 83  PRO B CG  1 
ATOM   4079 C  CD  . PRO B 1 83  ? 123.928 98.529  113.991 1.00 71.68  ? 83  PRO B CD  1 
ATOM   4080 N  N   . LEU B 1 84  ? 119.823 98.665  111.798 1.00 72.90  ? 84  LEU B N   1 
ATOM   4081 C  CA  . LEU B 1 84  ? 119.161 99.348  110.694 1.00 72.90  ? 84  LEU B CA  1 
ATOM   4082 C  C   . LEU B 1 84  ? 119.055 100.841 110.955 1.00 72.90  ? 84  LEU B C   1 
ATOM   4083 O  O   . LEU B 1 84  ? 119.094 101.648 110.023 1.00 72.90  ? 84  LEU B O   1 
ATOM   4084 C  CB  . LEU B 1 84  ? 117.780 98.745  110.463 1.00 72.90  ? 84  LEU B CB  1 
ATOM   4085 C  CG  . LEU B 1 84  ? 117.061 99.164  109.186 1.00 72.90  ? 84  LEU B CG  1 
ATOM   4086 C  CD1 . LEU B 1 84  ? 117.671 98.480  107.993 1.00 72.90  ? 84  LEU B CD1 1 
ATOM   4087 C  CD2 . LEU B 1 84  ? 115.590 98.852  109.284 1.00 72.90  ? 84  LEU B CD2 1 
ATOM   4088 N  N   . GLU B 1 85  ? 118.945 101.229 112.222 1.00 74.50  ? 85  GLU B N   1 
ATOM   4089 C  CA  . GLU B 1 85  ? 118.853 102.639 112.566 1.00 74.50  ? 85  GLU B CA  1 
ATOM   4090 C  C   . GLU B 1 85  ? 120.199 103.342 112.502 1.00 74.50  ? 85  GLU B C   1 
ATOM   4091 O  O   . GLU B 1 85  ? 120.236 104.574 112.506 1.00 74.50  ? 85  GLU B O   1 
ATOM   4092 C  CB  . GLU B 1 85  ? 118.248 102.793 113.958 1.00 74.50  ? 85  GLU B CB  1 
ATOM   4093 C  CG  . GLU B 1 85  ? 119.197 102.495 115.093 1.00 74.50  ? 85  GLU B CG  1 
ATOM   4094 C  CD  . GLU B 1 85  ? 118.984 101.125 115.694 1.00 74.50  ? 85  GLU B CD  1 
ATOM   4095 O  OE1 . GLU B 1 85  ? 118.304 100.295 115.061 1.00 74.50  ? 85  GLU B OE1 1 
ATOM   4096 O  OE2 . GLU B 1 85  ? 119.497 100.876 116.803 1.00 74.50  ? 85  GLU B OE2 1 
ATOM   4097 N  N   . ASP B 1 86  ? 121.294 102.598 112.438 1.00 74.16  ? 86  ASP B N   1 
ATOM   4098 C  CA  . ASP B 1 86  ? 122.631 103.164 112.408 1.00 74.16  ? 86  ASP B CA  1 
ATOM   4099 C  C   . ASP B 1 86  ? 123.215 103.078 111.009 1.00 74.16  ? 86  ASP B C   1 
ATOM   4100 O  O   . ASP B 1 86  ? 122.941 102.141 110.258 1.00 74.16  ? 86  ASP B O   1 
ATOM   4101 C  CB  . ASP B 1 86  ? 123.553 102.435 113.381 1.00 74.16  ? 86  ASP B CB  1 
ATOM   4102 C  CG  . ASP B 1 86  ? 123.332 102.848 114.811 1.00 74.16  ? 86  ASP B CG  1 
ATOM   4103 O  OD1 . ASP B 1 86  ? 122.515 103.757 115.051 1.00 74.16  ? 86  ASP B OD1 1 
ATOM   4104 O  OD2 . ASP B 1 86  ? 123.978 102.266 115.702 1.00 74.16  ? 86  ASP B OD2 1 
ATOM   4105 N  N   . ALA B 1 87  ? 124.027 104.066 110.666 1.00 69.45  ? 87  ALA B N   1 
ATOM   4106 C  CA  . ALA B 1 87  ? 124.823 104.029 109.452 1.00 69.45  ? 87  ALA B CA  1 
ATOM   4107 C  C   . ALA B 1 87  ? 126.213 103.530 109.805 1.00 69.45  ? 87  ALA B C   1 
ATOM   4108 O  O   . ALA B 1 87  ? 126.784 103.943 110.816 1.00 69.45  ? 87  ALA B O   1 
ATOM   4109 C  CB  . ALA B 1 87  ? 124.899 105.406 108.797 1.00 69.45  ? 87  ALA B CB  1 
ATOM   4110 N  N   . ALA B 1 88  ? 126.743 102.627 108.990 1.00 67.87  ? 88  ALA B N   1 
ATOM   4111 C  CA  . ALA B 1 88  ? 128.087 102.125 109.215 1.00 67.87  ? 88  ALA B CA  1 
ATOM   4112 C  C   . ALA B 1 88  ? 129.109 103.150 108.762 1.00 67.87  ? 88  ALA B C   1 
ATOM   4113 O  O   . ALA B 1 88  ? 128.972 103.747 107.699 1.00 67.87  ? 88  ALA B O   1 
ATOM   4114 C  CB  . ALA B 1 88  ? 128.298 100.822 108.461 1.00 67.87  ? 88  ALA B CB  1 
ATOM   4115 N  N   . ILE B 1 89  ? 130.143 103.348 109.567 1.00 66.76  ? 89  ILE B N   1 
ATOM   4116 C  CA  . ILE B 1 89  ? 131.208 104.288 109.251 1.00 66.76  ? 89  ILE B CA  1 
ATOM   4117 C  C   . ILE B 1 89  ? 132.353 103.508 108.627 1.00 66.76  ? 89  ILE B C   1 
ATOM   4118 O  O   . ILE B 1 89  ? 132.940 102.632 109.266 1.00 66.76  ? 89  ILE B O   1 
ATOM   4119 C  CB  . ILE B 1 89  ? 131.661 105.060 110.493 1.00 66.76  ? 89  ILE B CB  1 
ATOM   4120 C  CG1 . ILE B 1 89  ? 130.448 105.631 111.213 1.00 66.76  ? 89  ILE B CG1 1 
ATOM   4121 C  CG2 . ILE B 1 89  ? 132.593 106.170 110.107 1.00 66.76  ? 89  ILE B CG2 1 
ATOM   4122 C  CD1 . ILE B 1 89  ? 130.730 106.071 112.603 1.00 66.76  ? 89  ILE B CD1 1 
ATOM   4123 N  N   . ILE B 1 90  ? 132.672 103.825 107.383 1.00 67.86  ? 90  ILE B N   1 
ATOM   4124 C  CA  . ILE B 1 90  ? 133.651 103.087 106.599 1.00 67.86  ? 90  ILE B CA  1 
ATOM   4125 C  C   . ILE B 1 90  ? 134.924 103.900 106.506 1.00 67.86  ? 90  ILE B C   1 
ATOM   4126 O  O   . ILE B 1 90  ? 134.947 104.934 105.842 1.00 67.86  ? 90  ILE B O   1 
ATOM   4127 C  CB  . ILE B 1 90  ? 133.111 102.791 105.192 1.00 67.86  ? 90  ILE B CB  1 
ATOM   4128 C  CG1 . ILE B 1 90  ? 131.769 102.079 105.271 1.00 67.86  ? 90  ILE B CG1 1 
ATOM   4129 C  CG2 . ILE B 1 90  ? 134.111 101.991 104.408 1.00 67.86  ? 90  ILE B CG2 1 
ATOM   4130 C  CD1 . ILE B 1 90  ? 131.843 100.779 105.936 1.00 67.86  ? 90  ILE B CD1 1 
ATOM   4131 N  N   . PHE B 1 91  ? 135.992 103.427 107.131 1.00 69.71  ? 91  PHE B N   1 
ATOM   4132 C  CA  . PHE B 1 91  ? 137.277 104.106 107.072 1.00 69.71  ? 91  PHE B CA  1 
ATOM   4133 C  C   . PHE B 1 91  ? 138.115 103.493 105.968 1.00 69.71  ? 91  PHE B C   1 
ATOM   4134 O  O   . PHE B 1 91  ? 138.431 102.306 106.020 1.00 69.71  ? 91  PHE B O   1 
ATOM   4135 C  CB  . PHE B 1 91  ? 138.027 104.010 108.396 1.00 69.71  ? 91  PHE B CB  1 
ATOM   4136 C  CG  . PHE B 1 91  ? 139.432 104.506 108.319 1.00 69.71  ? 91  PHE B CG  1 
ATOM   4137 C  CD1 . PHE B 1 91  ? 139.688 105.854 108.225 1.00 69.71  ? 91  PHE B CD1 1 
ATOM   4138 C  CD2 . PHE B 1 91  ? 140.498 103.626 108.332 1.00 69.71  ? 91  PHE B CD2 1 
ATOM   4139 C  CE1 . PHE B 1 91  ? 140.974 106.316 108.147 1.00 69.71  ? 91  PHE B CE1 1 
ATOM   4140 C  CE2 . PHE B 1 91  ? 141.785 104.087 108.248 1.00 69.71  ? 91  PHE B CE2 1 
ATOM   4141 C  CZ  . PHE B 1 91  ? 142.023 105.431 108.157 1.00 69.71  ? 91  PHE B CZ  1 
ATOM   4142 N  N   . VAL B 1 92  ? 138.504 104.303 104.995 1.00 70.25  ? 92  VAL B N   1 
ATOM   4143 C  CA  . VAL B 1 92  ? 139.356 103.868 103.897 1.00 70.25  ? 92  VAL B CA  1 
ATOM   4144 C  C   . VAL B 1 92  ? 140.752 104.426 104.139 1.00 70.25  ? 92  VAL B C   1 
ATOM   4145 O  O   . VAL B 1 92  ? 140.913 105.644 104.242 1.00 70.25  ? 92  VAL B O   1 
ATOM   4146 C  CB  . VAL B 1 92  ? 138.815 104.324 102.535 1.00 70.25  ? 92  VAL B CB  1 
ATOM   4147 C  CG1 . VAL B 1 92  ? 139.721 103.850 101.433 1.00 70.25  ? 92  VAL B CG1 1 
ATOM   4148 C  CG2 . VAL B 1 92  ? 137.423 103.803 102.328 1.00 70.25  ? 92  VAL B CG2 1 
ATOM   4149 N  N   . PRO B 1 93  ? 141.780 103.585 104.246 1.00 72.24  ? 93  PRO B N   1 
ATOM   4150 C  CA  . PRO B 1 93  ? 143.135 104.082 104.517 1.00 72.24  ? 93  PRO B CA  1 
ATOM   4151 C  C   . PRO B 1 93  ? 143.728 104.755 103.290 1.00 72.24  ? 93  PRO B C   1 
ATOM   4152 O  O   . PRO B 1 93  ? 143.852 104.144 102.229 1.00 72.24  ? 93  PRO B O   1 
ATOM   4153 C  CB  . PRO B 1 93  ? 143.909 102.814 104.890 1.00 72.24  ? 93  PRO B CB  1 
ATOM   4154 C  CG  . PRO B 1 93  ? 142.875 101.784 105.147 1.00 72.24  ? 93  PRO B CG  1 
ATOM   4155 C  CD  . PRO B 1 93  ? 141.731 102.120 104.272 1.00 72.24  ? 93  PRO B CD  1 
ATOM   4156 N  N   . LEU B 1 94  ? 144.091 106.011 103.441 1.00 76.36  ? 94  LEU B N   1 
ATOM   4157 C  CA  . LEU B 1 94  ? 144.691 106.802 102.380 1.00 76.36  ? 94  LEU B CA  1 
ATOM   4158 C  C   . LEU B 1 94  ? 145.528 107.900 103.015 1.00 76.36  ? 94  LEU B C   1 
ATOM   4159 O  O   . LEU B 1 94  ? 144.973 108.906 103.466 1.00 76.36  ? 94  LEU B O   1 
ATOM   4160 C  CB  . LEU B 1 94  ? 143.620 107.401 101.475 1.00 76.36  ? 94  LEU B CB  1 
ATOM   4161 C  CG  . LEU B 1 94  ? 144.122 108.171 100.262 1.00 76.36  ? 94  LEU B CG  1 
ATOM   4162 C  CD1 . LEU B 1 94  ? 144.686 107.218 99.244  1.00 76.36  ? 94  LEU B CD1 1 
ATOM   4163 C  CD2 . LEU B 1 94  ? 143.002 108.975 99.664  1.00 76.36  ? 94  LEU B CD2 1 
ATOM   4164 N  N   . PRO B 1 95  ? 146.847 107.738 103.089 1.00 79.61  ? 95  PRO B N   1 
ATOM   4165 C  CA  . PRO B 1 95  ? 147.677 108.714 103.808 1.00 79.61  ? 95  PRO B CA  1 
ATOM   4166 C  C   . PRO B 1 95  ? 147.737 110.050 103.083 1.00 79.61  ? 95  PRO B C   1 
ATOM   4167 O  O   . PRO B 1 95  ? 148.169 110.136 101.933 1.00 79.61  ? 95  PRO B O   1 
ATOM   4168 C  CB  . PRO B 1 95  ? 149.049 108.037 103.867 1.00 79.61  ? 95  PRO B CB  1 
ATOM   4169 C  CG  . PRO B 1 95  ? 149.033 107.046 102.772 1.00 79.61  ? 95  PRO B CG  1 
ATOM   4170 C  CD  . PRO B 1 95  ? 147.628 106.581 102.629 1.00 79.61  ? 95  PRO B CD  1 
ATOM   4171 N  N   . GLY B 1 96  ? 147.292 111.095 103.772 1.00 80.08  ? 96  GLY B N   1 
ATOM   4172 C  CA  . GLY B 1 96  ? 147.110 112.392 103.179 1.00 80.08  ? 96  GLY B CA  1 
ATOM   4173 C  C   . GLY B 1 96  ? 145.668 112.777 102.942 1.00 80.08  ? 96  GLY B C   1 
ATOM   4174 O  O   . GLY B 1 96  ? 145.360 113.970 102.901 1.00 80.08  ? 96  GLY B O   1 
ATOM   4175 N  N   . GLY B 1 97  ? 144.779 111.806 102.791 1.00 76.87  ? 97  GLY B N   1 
ATOM   4176 C  CA  . GLY B 1 97  ? 143.377 112.088 102.613 1.00 76.87  ? 97  GLY B CA  1 
ATOM   4177 C  C   . GLY B 1 97  ? 143.038 112.543 101.208 1.00 76.87  ? 97  GLY B C   1 
ATOM   4178 O  O   . GLY B 1 97  ? 143.855 112.534 100.292 1.00 76.87  ? 97  GLY B O   1 
ATOM   4179 N  N   . LEU B 1 98  ? 141.799 112.944 101.057 1.00 74.24  ? 98  LEU B N   1 
ATOM   4180 C  CA  . LEU B 1 98  ? 141.260 113.461 99.814  1.00 74.24  ? 98  LEU B CA  1 
ATOM   4181 C  C   . LEU B 1 98  ? 141.379 114.975 99.772  1.00 74.24  ? 98  LEU B C   1 
ATOM   4182 O  O   . LEU B 1 98  ? 141.446 115.631 100.812 1.00 74.24  ? 98  LEU B O   1 
ATOM   4183 C  CB  . LEU B 1 98  ? 139.799 113.057 99.675  1.00 74.24  ? 98  LEU B CB  1 
ATOM   4184 C  CG  . LEU B 1 98  ? 139.530 111.566 99.573  1.00 74.24  ? 98  LEU B CG  1 
ATOM   4185 C  CD1 . LEU B 1 98  ? 138.052 111.320 99.627  1.00 74.24  ? 98  LEU B CD1 1 
ATOM   4186 C  CD2 . LEU B 1 98  ? 140.108 111.032 98.294  1.00 74.24  ? 98  LEU B CD2 1 
ATOM   4187 N  N   . PRO B 1 99  ? 141.429 115.566 98.584  1.00 76.59  ? 99  PRO B N   1 
ATOM   4188 C  CA  . PRO B 1 99  ? 141.321 117.020 98.484  1.00 76.59  ? 99  PRO B CA  1 
ATOM   4189 C  C   . PRO B 1 99  ? 139.885 117.480 98.673  1.00 76.59  ? 99  PRO B C   1 
ATOM   4190 O  O   . PRO B 1 99  ? 138.946 116.686 98.716  1.00 76.59  ? 99  PRO B O   1 
ATOM   4191 C  CB  . PRO B 1 99  ? 141.811 117.311 97.064  1.00 76.59  ? 99  PRO B CB  1 
ATOM   4192 C  CG  . PRO B 1 99  ? 141.574 116.068 96.331  1.00 76.59  ? 99  PRO B CG  1 
ATOM   4193 C  CD  . PRO B 1 99  ? 141.810 114.965 97.297  1.00 76.59  ? 99  PRO B CD  1 
ATOM   4194 N  N   . ASP B 1 100 ? 139.730 118.792 98.802  1.00 80.33  ? 100 ASP B N   1 
ATOM   4195 C  CA  . ASP B 1 100 ? 138.405 119.376 98.932  1.00 80.33  ? 100 ASP B CA  1 
ATOM   4196 C  C   . ASP B 1 100 ? 137.647 119.282 97.618  1.00 80.33  ? 100 ASP B C   1 
ATOM   4197 O  O   . ASP B 1 100 ? 138.234 119.333 96.536  1.00 80.33  ? 100 ASP B O   1 
ATOM   4198 C  CB  . ASP B 1 100 ? 138.510 120.837 99.358  1.00 80.33  ? 100 ASP B CB  1 
ATOM   4199 C  CG  . ASP B 1 100 ? 138.432 121.017 100.849 1.00 80.33  ? 100 ASP B CG  1 
ATOM   4200 O  OD1 . ASP B 1 100 ? 137.627 120.317 101.490 1.00 80.33  ? 100 ASP B OD1 1 
ATOM   4201 O  OD2 . ASP B 1 100 ? 139.171 121.864 101.381 1.00 80.33  ? 100 ASP B OD2 1 
ATOM   4202 N  N   . GLY B 1 101 ? 136.340 119.140 97.713  1.00 75.50  ? 101 GLY B N   1 
ATOM   4203 C  CA  . GLY B 1 101 ? 135.493 119.217 96.546  1.00 75.50  ? 101 GLY B CA  1 
ATOM   4204 C  C   . GLY B 1 101 ? 134.481 118.096 96.534  1.00 75.50  ? 101 GLY B C   1 
ATOM   4205 O  O   . GLY B 1 101 ? 134.258 117.423 97.531  1.00 75.50  ? 101 GLY B O   1 
ATOM   4206 N  N   . VAL B 1 102 ? 133.872 117.919 95.371  1.00 73.75  ? 102 VAL B N   1 
ATOM   4207 C  CA  . VAL B 1 102 ? 132.867 116.892 95.146  1.00 73.75  ? 102 VAL B CA  1 
ATOM   4208 C  C   . VAL B 1 102 ? 133.547 115.717 94.467  1.00 73.75  ? 102 VAL B C   1 
ATOM   4209 O  O   . VAL B 1 102 ? 134.234 115.887 93.454  1.00 73.75  ? 102 VAL B O   1 
ATOM   4210 C  CB  . VAL B 1 102 ? 131.704 117.424 94.298  1.00 73.75  ? 102 VAL B CB  1 
ATOM   4211 C  CG1 . VAL B 1 102 ? 130.558 116.462 94.332  1.00 73.75  ? 102 VAL B CG1 1 
ATOM   4212 C  CG2 . VAL B 1 102 ? 131.265 118.765 94.806  1.00 73.75  ? 102 VAL B CG2 1 
ATOM   4213 N  N   . HIS B 1 103 ? 133.367 114.530 95.024  1.00 72.65  ? 103 HIS B N   1 
ATOM   4214 C  CA  . HIS B 1 103 ? 133.987 113.326 94.506  1.00 72.65  ? 103 HIS B CA  1 
ATOM   4215 C  C   . HIS B 1 103 ? 132.917 112.352 94.049  1.00 72.65  ? 103 HIS B C   1 
ATOM   4216 O  O   . HIS B 1 103 ? 131.867 112.224 94.678  1.00 72.65  ? 103 HIS B O   1 
ATOM   4217 C  CB  . HIS B 1 103 ? 134.873 112.667 95.560  1.00 72.65  ? 103 HIS B CB  1 
ATOM   4218 C  CG  . HIS B 1 103 ? 136.003 113.530 96.015  1.00 72.65  ? 103 HIS B CG  1 
ATOM   4219 N  ND1 . HIS B 1 103 ? 137.136 113.726 95.262  1.00 72.65  ? 103 HIS B ND1 1 
ATOM   4220 C  CD2 . HIS B 1 103 ? 136.169 114.257 97.142  1.00 72.65  ? 103 HIS B CD2 1 
ATOM   4221 C  CE1 . HIS B 1 103 ? 137.955 114.535 95.906  1.00 72.65  ? 103 HIS B CE1 1 
ATOM   4222 N  NE2 . HIS B 1 103 ? 137.391 114.873 97.049  1.00 72.65  ? 103 HIS B NE2 1 
ATOM   4223 N  N   . GLU B 1 104 ? 133.190 111.673 92.946  1.00 76.10  ? 104 GLU B N   1 
ATOM   4224 C  CA  . GLU B 1 104 ? 132.308 110.633 92.443  1.00 76.10  ? 104 GLU B CA  1 
ATOM   4225 C  C   . GLU B 1 104 ? 132.649 109.341 93.168  1.00 76.10  ? 104 GLU B C   1 
ATOM   4226 O  O   . GLU B 1 104 ? 133.536 108.599 92.746  1.00 76.10  ? 104 GLU B O   1 
ATOM   4227 C  CB  . GLU B 1 104 ? 132.460 110.482 90.937  1.00 76.10  ? 104 GLU B CB  1 
ATOM   4228 C  CG  . GLU B 1 104 ? 131.249 109.900 90.268  1.00 76.10  ? 104 GLU B CG  1 
ATOM   4229 C  CD  . GLU B 1 104 ? 131.504 109.557 88.824  1.00 76.10  ? 104 GLU B CD  1 
ATOM   4230 O  OE1 . GLU B 1 104 ? 132.655 109.214 88.490  1.00 76.10  ? 104 GLU B OE1 1 
ATOM   4231 O  OE2 . GLU B 1 104 ? 130.556 109.633 88.018  1.00 76.10  ? 104 GLU B OE2 1 
ATOM   4232 N  N   . LEU B 1 105 ? 131.948 109.075 94.257  1.00 71.68  ? 105 LEU B N   1 
ATOM   4233 C  CA  . LEU B 1 105 ? 132.246 107.949 95.123  1.00 71.68  ? 105 LEU B CA  1 
ATOM   4234 C  C   . LEU B 1 105 ? 131.402 106.759 94.707  1.00 71.68  ? 105 LEU B C   1 
ATOM   4235 O  O   . LEU B 1 105 ? 130.174 106.843 94.685  1.00 71.68  ? 105 LEU B O   1 
ATOM   4236 C  CB  . LEU B 1 105 ? 131.976 108.318 96.579  1.00 71.68  ? 105 LEU B CB  1 
ATOM   4237 C  CG  . LEU B 1 105 ? 132.151 107.250 97.647  1.00 71.68  ? 105 LEU B CG  1 
ATOM   4238 C  CD1 . LEU B 1 105 ? 133.526 106.685 97.577  1.00 71.68  ? 105 LEU B CD1 1 
ATOM   4239 C  CD2 . LEU B 1 105 ? 131.916 107.850 99.002  1.00 71.68  ? 105 LEU B CD2 1 
ATOM   4240 N  N   . SER B 1 106 ? 132.061 105.658 94.371  1.00 72.18  ? 106 SER B N   1 
ATOM   4241 C  CA  . SER B 1 106 ? 131.395 104.436 93.954  1.00 72.18  ? 106 SER B CA  1 
ATOM   4242 C  C   . SER B 1 106 ? 131.743 103.325 94.926  1.00 72.18  ? 106 SER B C   1 
ATOM   4243 O  O   . SER B 1 106 ? 132.920 103.016 95.117  1.00 72.18  ? 106 SER B O   1 
ATOM   4244 C  CB  . SER B 1 106 ? 131.812 104.037 92.542  1.00 72.18  ? 106 SER B CB  1 
ATOM   4245 O  OG  . SER B 1 106 ? 131.428 105.019 91.603  1.00 72.18  ? 106 SER B OG  1 
ATOM   4246 N  N   . ILE B 1 107 ? 130.731 102.726 95.534  1.00 71.50  ? 107 ILE B N   1 
ATOM   4247 C  CA  . ILE B 1 107 ? 130.953 101.618 96.448  1.00 71.50  ? 107 ILE B CA  1 
ATOM   4248 C  C   . ILE B 1 107 ? 130.412 100.344 95.823  1.00 71.50  ? 107 ILE B C   1 
ATOM   4249 O  O   . ILE B 1 107 ? 129.597 100.374 94.898  1.00 71.50  ? 107 ILE B O   1 
ATOM   4250 C  CB  . ILE B 1 107 ? 130.325 101.849 97.835  1.00 71.50  ? 107 ILE B CB  1 
ATOM   4251 C  CG1 . ILE B 1 107 ? 128.809 101.729 97.763  1.00 71.50  ? 107 ILE B CG1 1 
ATOM   4252 C  CG2 . ILE B 1 107 ? 130.742 103.187 98.384  1.00 71.50  ? 107 ILE B CG2 1 
ATOM   4253 C  CD1 . ILE B 1 107 ? 128.135 101.755 99.089  1.00 71.50  ? 107 ILE B CD1 1 
ATOM   4254 N  N   . GLU B 1 108 ? 130.908 99.217  96.317  1.00 75.67  ? 108 GLU B N   1 
ATOM   4255 C  CA  . GLU B 1 108 ? 130.439 97.887  95.933  1.00 75.67  ? 108 GLU B CA  1 
ATOM   4256 C  C   . GLU B 1 108 ? 130.300 97.083  97.220  1.00 75.67  ? 108 GLU B C   1 
ATOM   4257 O  O   . GLU B 1 108 ? 131.229 96.404  97.653  1.00 75.67  ? 108 GLU B O   1 
ATOM   4258 C  CB  . GLU B 1 108 ? 131.386 97.241  94.955  1.00 75.67  ? 108 GLU B CB  1 
ATOM   4259 C  CG  . GLU B 1 108 ? 130.899 95.924  94.419  1.00 75.67  ? 108 GLU B CG  1 
ATOM   4260 C  CD  . GLU B 1 108 ? 132.026 95.050  93.922  1.00 75.67  ? 108 GLU B CD  1 
ATOM   4261 O  OE1 . GLU B 1 108 ? 132.676 95.433  92.928  1.00 75.67  ? 108 GLU B OE1 1 
ATOM   4262 O  OE2 . GLU B 1 108 ? 132.266 93.981  94.523  1.00 75.67  ? 108 GLU B OE2 1 
ATOM   4263 N  N   . LEU B 1 109 ? 129.131 97.171  97.836  1.00 73.13  ? 109 LEU B N   1 
ATOM   4264 C  CA  . LEU B 1 109 ? 128.914 96.557  99.133  1.00 73.13  ? 109 LEU B CA  1 
ATOM   4265 C  C   . LEU B 1 109 ? 128.405 95.136  98.972  1.00 73.13  ? 109 LEU B C   1 
ATOM   4266 O  O   . LEU B 1 109 ? 127.514 94.872  98.169  1.00 73.13  ? 109 LEU B O   1 
ATOM   4267 C  CB  . LEU B 1 109 ? 127.917 97.384  99.933  1.00 73.13  ? 109 LEU B CB  1 
ATOM   4268 C  CG  . LEU B 1 109 ? 127.367 96.811  101.229 1.00 73.13  ? 109 LEU B CG  1 
ATOM   4269 C  CD1 . LEU B 1 109 ? 128.463 96.655  102.246 1.00 73.13  ? 109 LEU B CD1 1 
ATOM   4270 C  CD2 . LEU B 1 109 ? 126.295 97.718  101.744 1.00 73.13  ? 109 LEU B CD2 1 
ATOM   4271 N  N   . ARG B 1 110 ? 128.973 94.217  99.744  1.00 75.75  ? 110 ARG B N   1 
ATOM   4272 C  CA  . ARG B 1 110 ? 128.596 92.813  99.693  1.00 75.75  ? 110 ARG B CA  1 
ATOM   4273 C  C   . ARG B 1 110 ? 128.061 92.367  101.042 1.00 75.75  ? 110 ARG B C   1 
ATOM   4274 O  O   . ARG B 1 110 ? 128.716 92.562  102.066 1.00 75.75  ? 110 ARG B O   1 
ATOM   4275 C  CB  . ARG B 1 110 ? 129.775 91.942  99.304  1.00 75.75  ? 110 ARG B CB  1 
ATOM   4276 C  CG  . ARG B 1 110 ? 130.366 92.260  97.980  1.00 75.75  ? 110 ARG B CG  1 
ATOM   4277 C  CD  . ARG B 1 110 ? 131.503 91.325  97.732  1.00 75.75  ? 110 ARG B CD  1 
ATOM   4278 N  NE  . ARG B 1 110 ? 132.256 91.683  96.544  1.00 75.75  ? 110 ARG B NE  1 
ATOM   4279 C  CZ  . ARG B 1 110 ? 133.368 91.068  96.174  1.00 75.75  ? 110 ARG B CZ  1 
ATOM   4280 N  NH1 . ARG B 1 110 ? 133.842 90.073  96.906  1.00 75.75  ? 110 ARG B NH1 1 
ATOM   4281 N  NH2 . ARG B 1 110 ? 134.006 91.448  95.080  1.00 75.75  ? 110 ARG B NH2 1 
ATOM   4282 N  N   . LEU B 1 111 ? 126.883 91.762  101.037 1.00 74.98  ? 111 LEU B N   1 
ATOM   4283 C  CA  . LEU B 1 111 ? 126.275 91.211  102.234 1.00 74.98  ? 111 LEU B CA  1 
ATOM   4284 C  C   . LEU B 1 111 ? 125.873 89.776  101.960 1.00 74.98  ? 111 LEU B C   1 
ATOM   4285 O  O   . LEU B 1 111 ? 125.471 89.441  100.847 1.00 74.98  ? 111 LEU B O   1 
ATOM   4286 C  CB  . LEU B 1 111 ? 125.047 92.005  102.658 1.00 74.98  ? 111 LEU B CB  1 
ATOM   4287 C  CG  . LEU B 1 111 ? 125.226 93.490  102.932 1.00 74.98  ? 111 LEU B CG  1 
ATOM   4288 C  CD1 . LEU B 1 111 ? 123.885 94.133  103.147 1.00 74.98  ? 111 LEU B CD1 1 
ATOM   4289 C  CD2 . LEU B 1 111 ? 126.104 93.688  104.136 1.00 74.98  ? 111 LEU B CD2 1 
ATOM   4290 N  N   . ARG B 1 112 ? 125.977 88.930  102.974 1.00 75.99  ? 112 ARG B N   1 
ATOM   4291 C  CA  . ARG B 1 112 ? 125.586 87.533  102.856 1.00 75.99  ? 112 ARG B CA  1 
ATOM   4292 C  C   . ARG B 1 112 ? 124.199 87.342  103.452 1.00 75.99  ? 112 ARG B C   1 
ATOM   4293 O  O   . ARG B 1 112 ? 124.001 87.548  104.650 1.00 75.99  ? 112 ARG B O   1 
ATOM   4294 C  CB  . ARG B 1 112 ? 126.594 86.620  103.547 1.00 75.99  ? 112 ARG B CB  1 
ATOM   4295 C  CG  . ARG B 1 112 ? 127.981 86.720  102.985 1.00 75.99  ? 112 ARG B CG  1 
ATOM   4296 C  CD  . ARG B 1 112 ? 128.813 85.515  103.349 1.00 75.99  ? 112 ARG B CD  1 
ATOM   4297 N  NE  . ARG B 1 112 ? 128.735 85.195  104.765 1.00 75.99  ? 112 ARG B NE  1 
ATOM   4298 C  CZ  . ARG B 1 112 ? 129.472 85.771  105.703 1.00 75.99  ? 112 ARG B CZ  1 
ATOM   4299 N  NH1 . ARG B 1 112 ? 130.345 86.706  105.383 1.00 75.99  ? 112 ARG B NH1 1 
ATOM   4300 N  NH2 . ARG B 1 112 ? 129.334 85.414  106.964 1.00 75.99  ? 112 ARG B NH2 1 
ATOM   4301 N  N   . MET B 1 113 ? 123.247 86.959  102.613 1.00 81.64  ? 113 MET B N   1 
ATOM   4302 C  CA  . MET B 1 113 ? 121.919 86.559  103.046 1.00 81.64  ? 113 MET B CA  1 
ATOM   4303 C  C   . MET B 1 113 ? 121.862 85.042  103.009 1.00 81.64  ? 113 MET B C   1 
ATOM   4304 O  O   . MET B 1 113 ? 122.163 84.437  101.979 1.00 81.64  ? 113 MET B O   1 
ATOM   4305 C  CB  . MET B 1 113 ? 120.847 87.156  102.142 1.00 81.64  ? 113 MET B CB  1 
ATOM   4306 C  CG  . MET B 1 113 ? 121.120 88.567  101.686 1.00 81.64  ? 113 MET B CG  1 
ATOM   4307 S  SD  . MET B 1 113 ? 121.092 89.755  103.024 1.00 81.64  ? 113 MET B SD  1 
ATOM   4308 C  CE  . MET B 1 113 ? 121.379 91.265  102.120 1.00 81.64  ? 113 MET B CE  1 
ATOM   4309 N  N   . SER B 1 114 ? 121.488 84.427  104.126 1.00 82.57  ? 114 SER B N   1 
ATOM   4310 C  CA  . SER B 1 114 ? 121.559 82.975  104.211 1.00 82.57  ? 114 SER B CA  1 
ATOM   4311 C  C   . SER B 1 114 ? 120.394 82.287  103.518 1.00 82.57  ? 114 SER B C   1 
ATOM   4312 O  O   . SER B 1 114 ? 120.509 81.112  103.167 1.00 82.57  ? 114 SER B O   1 
ATOM   4313 C  CB  . SER B 1 114 ? 121.621 82.542  105.669 1.00 82.57  ? 114 SER B CB  1 
ATOM   4314 O  OG  . SER B 1 114 ? 122.533 83.350  106.383 1.00 82.57  ? 114 SER B OG  1 
ATOM   4315 N  N   . TYR B 1 115 ? 119.293 82.986  103.298 1.00 82.59  ? 115 TYR B N   1 
ATOM   4316 C  CA  . TYR B 1 115 ? 118.098 82.405  102.709 1.00 82.59  ? 115 TYR B CA  1 
ATOM   4317 C  C   . TYR B 1 115 ? 118.106 82.449  101.191 1.00 82.59  ? 115 TYR B C   1 
ATOM   4318 O  O   . TYR B 1 115 ? 117.124 82.041  100.569 1.00 82.59  ? 115 TYR B O   1 
ATOM   4319 C  CB  . TYR B 1 115 ? 116.854 83.120  103.245 1.00 82.59  ? 115 TYR B CB  1 
ATOM   4320 C  CG  . TYR B 1 115 ? 116.970 84.624  103.270 1.00 82.59  ? 115 TYR B CG  1 
ATOM   4321 C  CD1 . TYR B 1 115 ? 116.653 85.377  102.156 1.00 82.59  ? 115 TYR B CD1 1 
ATOM   4322 C  CD2 . TYR B 1 115 ? 117.387 85.289  104.414 1.00 82.59  ? 115 TYR B CD2 1 
ATOM   4323 C  CE1 . TYR B 1 115 ? 116.758 86.737  102.170 1.00 82.59  ? 115 TYR B CE1 1 
ATOM   4324 C  CE2 . TYR B 1 115 ? 117.502 86.650  104.433 1.00 82.59  ? 115 TYR B CE2 1 
ATOM   4325 C  CZ  . TYR B 1 115 ? 117.186 87.367  103.309 1.00 82.59  ? 115 TYR B CZ  1 
ATOM   4326 O  OH  . TYR B 1 115 ? 117.286 88.734  103.326 1.00 82.59  ? 115 TYR B OH  1 
ATOM   4327 N  N   . ILE B 1 116 ? 119.180 82.937  100.587 1.00 85.83  ? 116 ILE B N   1 
ATOM   4328 C  CA  . ILE B 1 116 ? 119.323 83.035  99.139  1.00 85.83  ? 116 ILE B CA  1 
ATOM   4329 C  C   . ILE B 1 116 ? 120.277 81.922  98.725  1.00 85.83  ? 116 ILE B C   1 
ATOM   4330 O  O   . ILE B 1 116 ? 121.216 81.630  99.477  1.00 85.83  ? 116 ILE B O   1 
ATOM   4331 C  CB  . ILE B 1 116 ? 119.820 84.437  98.747  1.00 85.83  ? 116 ILE B CB  1 
ATOM   4332 C  CG1 . ILE B 1 116 ? 118.749 85.470  99.085  1.00 85.83  ? 116 ILE B CG1 1 
ATOM   4333 C  CG2 . ILE B 1 116 ? 120.185 84.539  97.281  1.00 85.83  ? 116 ILE B CG2 1 
ATOM   4334 C  CD1 . ILE B 1 116 ? 119.148 86.880  98.782  1.00 85.83  ? 116 ILE B CD1 1 
ATOM   4335 N  N   . PRO B 1 117 ? 120.044 81.233  97.600  1.00 90.41  ? 117 PRO B N   1 
ATOM   4336 C  CA  . PRO B 1 117 ? 120.963 80.173  97.169  1.00 90.41  ? 117 PRO B CA  1 
ATOM   4337 C  C   . PRO B 1 117 ? 122.363 80.689  96.882  1.00 90.41  ? 117 PRO B C   1 
ATOM   4338 O  O   . PRO B 1 117 ? 122.563 81.864  96.579  1.00 90.41  ? 117 PRO B O   1 
ATOM   4339 C  CB  . PRO B 1 117 ? 120.304 79.637  95.898  1.00 90.41  ? 117 PRO B CB  1 
ATOM   4340 C  CG  . PRO B 1 117 ? 118.884 79.907  96.087  1.00 90.41  ? 117 PRO B CG  1 
ATOM   4341 C  CD  . PRO B 1 117 ? 118.790 81.198  96.831  1.00 90.41  ? 117 PRO B CD  1 
ATOM   4342 N  N   . GLN B 1 118 ? 123.330 79.774  96.965  1.00 93.35  ? 118 GLN B N   1 
ATOM   4343 C  CA  . GLN B 1 118 ? 124.740 80.143  96.999  1.00 93.35  ? 118 GLN B CA  1 
ATOM   4344 C  C   . GLN B 1 118 ? 125.238 80.693  95.668  1.00 93.35  ? 118 GLN B C   1 
ATOM   4345 O  O   . GLN B 1 118 ? 126.224 81.436  95.637  1.00 93.35  ? 118 GLN B O   1 
ATOM   4346 C  CB  . GLN B 1 118 ? 125.562 78.925  97.408  1.00 93.35  ? 118 GLN B CB  1 
ATOM   4347 C  CG  . GLN B 1 118 ? 126.951 79.225  97.905  1.00 93.35  ? 118 GLN B CG  1 
ATOM   4348 C  CD  . GLN B 1 118 ? 126.958 79.752  99.312  1.00 93.35  ? 118 GLN B CD  1 
ATOM   4349 O  OE1 . GLN B 1 118 ? 126.675 79.022  100.260 1.00 93.35  ? 118 GLN B OE1 1 
ATOM   4350 N  NE2 . GLN B 1 118 ? 127.288 81.028  99.463  1.00 93.35  ? 118 GLN B NE2 1 
ATOM   4351 N  N   . GLU B 1 119 ? 124.571 80.359  94.564  1.00 96.29  ? 119 GLU B N   1 
ATOM   4352 C  CA  . GLU B 1 119 ? 125.042 80.812  93.259  1.00 96.29  ? 119 GLU B CA  1 
ATOM   4353 C  C   . GLU B 1 119 ? 124.766 82.295  93.047  1.00 96.29  ? 119 GLU B C   1 
ATOM   4354 O  O   . GLU B 1 119 ? 125.488 82.968  92.305  1.00 96.29  ? 119 GLU B O   1 
ATOM   4355 C  CB  . GLU B 1 119 ? 124.395 79.986  92.151  1.00 96.29  ? 119 GLU B CB  1 
ATOM   4356 C  CG  . GLU B 1 119 ? 122.888 79.889  92.249  1.00 96.29  ? 119 GLU B CG  1 
ATOM   4357 C  CD  . GLU B 1 119 ? 122.429 78.615  92.923  1.00 96.29  ? 119 GLU B CD  1 
ATOM   4358 O  OE1 . GLU B 1 119 ? 122.965 78.280  94.000  1.00 96.29  ? 119 GLU B OE1 1 
ATOM   4359 O  OE2 . GLU B 1 119 ? 121.530 77.948  92.375  1.00 96.29  ? 119 GLU B OE2 1 
ATOM   4360 N  N   . HIS B 1 120 ? 123.732 82.823  93.688  1.00 94.18  ? 120 HIS B N   1 
ATOM   4361 C  CA  . HIS B 1 120 ? 123.400 84.234  93.590  1.00 94.18  ? 120 HIS B CA  1 
ATOM   4362 C  C   . HIS B 1 120 ? 123.980 85.053  94.729  1.00 94.18  ? 120 HIS B C   1 
ATOM   4363 O  O   . HIS B 1 120 ? 123.472 86.139  95.013  1.00 94.18  ? 120 HIS B O   1 
ATOM   4364 C  CB  . HIS B 1 120 ? 121.886 84.412  93.552  1.00 94.18  ? 120 HIS B CB  1 
ATOM   4365 C  CG  . HIS B 1 120 ? 121.232 83.739  92.391  1.00 94.18  ? 120 HIS B CG  1 
ATOM   4366 N  ND1 . HIS B 1 120 ? 120.015 83.102  92.489  1.00 94.18  ? 120 HIS B ND1 1 
ATOM   4367 C  CD2 . HIS B 1 120 ? 121.628 83.599  91.105  1.00 94.18  ? 120 HIS B CD2 1 
ATOM   4368 C  CE1 . HIS B 1 120 ? 119.687 82.602  91.312  1.00 94.18  ? 120 HIS B CE1 1 
ATOM   4369 N  NE2 . HIS B 1 120 ? 120.649 82.890  90.454  1.00 94.18  ? 120 HIS B NE2 1 
ATOM   4370 N  N   . GLN B 1 121 ? 125.021 84.566  95.375  1.00 85.66  ? 121 GLN B N   1 
ATOM   4371 C  CA  . GLN B 1 121 ? 125.550 85.154  96.587  1.00 85.66  ? 121 GLN B CA  1 
ATOM   4372 C  C   . GLN B 1 121 ? 127.015 85.524  96.415  1.00 85.66  ? 121 GLN B C   1 
ATOM   4373 O  O   . GLN B 1 121 ? 127.747 84.860  95.678  1.00 85.66  ? 121 GLN B O   1 
ATOM   4374 C  CB  . GLN B 1 121 ? 125.387 84.171  97.749  1.00 85.66  ? 121 GLN B CB  1 
ATOM   4375 C  CG  . GLN B 1 121 ? 124.015 84.206  98.362  1.00 85.66  ? 121 GLN B CG  1 
ATOM   4376 C  CD  . GLN B 1 121 ? 123.694 85.534  98.983  1.00 85.66  ? 121 GLN B CD  1 
ATOM   4377 O  OE1 . GLN B 1 121 ? 122.809 86.251  98.528  1.00 85.66  ? 121 GLN B OE1 1 
ATOM   4378 N  NE2 . GLN B 1 121 ? 124.411 85.871  100.035 1.00 85.66  ? 121 GLN B NE2 1 
ATOM   4379 N  N   . PRO B 1 122 ? 127.492 86.588  97.083  1.00 80.00  ? 122 PRO B N   1 
ATOM   4380 C  CA  . PRO B 1 122 ? 126.814 87.501  98.005  1.00 80.00  ? 122 PRO B CA  1 
ATOM   4381 C  C   . PRO B 1 122 ? 125.975 88.550  97.307  1.00 80.00  ? 122 PRO B C   1 
ATOM   4382 O  O   . PRO B 1 122 ? 126.160 88.792  96.123  1.00 80.00  ? 122 PRO B O   1 
ATOM   4383 C  CB  . PRO B 1 122 ? 127.971 88.152  98.748  1.00 80.00  ? 122 PRO B CB  1 
ATOM   4384 C  CG  . PRO B 1 122 ? 129.055 88.148  97.786  1.00 80.00  ? 122 PRO B CG  1 
ATOM   4385 C  CD  . PRO B 1 122 ? 128.929 86.884  97.009  1.00 80.00  ? 122 PRO B CD  1 
ATOM   4386 N  N   . SER B 1 123 ? 125.038 89.134  98.044  1.00 78.06  ? 123 SER B N   1 
ATOM   4387 C  CA  . SER B 1 123 ? 124.241 90.229  97.519  1.00 78.06  ? 123 SER B CA  1 
ATOM   4388 C  C   . SER B 1 123 ? 125.116 91.454  97.337  1.00 78.06  ? 123 SER B C   1 
ATOM   4389 O  O   . SER B 1 123 ? 125.790 91.890  98.268  1.00 78.06  ? 123 SER B O   1 
ATOM   4390 C  CB  . SER B 1 123 ? 123.092 90.542  98.467  1.00 78.06  ? 123 SER B CB  1 
ATOM   4391 O  OG  . SER B 1 123 ? 122.172 89.474  98.516  1.00 78.06  ? 123 SER B OG  1 
ATOM   4392 N  N   . THR B 1 124 ? 125.107 92.013  96.137  1.00 75.16  ? 124 THR B N   1 
ATOM   4393 C  CA  . THR B 1 124 ? 125.985 93.114  95.780  1.00 75.16  ? 124 THR B CA  1 
ATOM   4394 C  C   . THR B 1 124 ? 125.150 94.361  95.549  1.00 75.16  ? 124 THR B C   1 
ATOM   4395 O  O   . THR B 1 124 ? 124.116 94.303  94.881  1.00 75.16  ? 124 THR B O   1 
ATOM   4396 C  CB  . THR B 1 124 ? 126.801 92.772  94.535  1.00 75.16  ? 124 THR B CB  1 
ATOM   4397 O  OG1 . THR B 1 124 ? 127.419 91.495  94.712  1.00 75.16  ? 124 THR B OG1 1 
ATOM   4398 C  CG2 . THR B 1 124 ? 127.880 93.788  94.318  1.00 75.16  ? 124 THR B CG2 1 
ATOM   4399 N  N   . TYR B 1 125 ? 125.588 95.477  96.117  1.00 73.74  ? 125 TYR B N   1 
ATOM   4400 C  CA  . TYR B 1 125 ? 124.920 96.759  95.963  1.00 73.74  ? 125 TYR B CA  1 
ATOM   4401 C  C   . TYR B 1 125 ? 125.937 97.759  95.447  1.00 73.74  ? 125 TYR B C   1 
ATOM   4402 O  O   . TYR B 1 125 ? 126.882 98.105  96.157  1.00 73.74  ? 125 TYR B O   1 
ATOM   4403 C  CB  . TYR B 1 125 ? 124.331 97.239  97.287  1.00 73.74  ? 125 TYR B CB  1 
ATOM   4404 C  CG  . TYR B 1 125 ? 123.358 96.280  97.916  1.00 73.74  ? 125 TYR B CG  1 
ATOM   4405 C  CD1 . TYR B 1 125 ? 123.788 95.308  98.804  1.00 73.74  ? 125 TYR B CD1 1 
ATOM   4406 C  CD2 . TYR B 1 125 ? 122.008 96.353  97.630  1.00 73.74  ? 125 TYR B CD2 1 
ATOM   4407 C  CE1 . TYR B 1 125 ? 122.906 94.430  99.376  1.00 73.74  ? 125 TYR B CE1 1 
ATOM   4408 C  CE2 . TYR B 1 125 ? 121.117 95.481  98.201  1.00 73.74  ? 125 TYR B CE2 1 
ATOM   4409 C  CZ  . TYR B 1 125 ? 121.573 94.523  99.072  1.00 73.74  ? 125 TYR B CZ  1 
ATOM   4410 O  OH  . TYR B 1 125 ? 120.684 93.651  99.646  1.00 73.74  ? 125 TYR B OH  1 
ATOM   4411 N  N   . ARG B 1 126 ? 125.750 98.217  94.219  1.00 76.68  ? 126 ARG B N   1 
ATOM   4412 C  CA  . ARG B 1 126 ? 126.632 99.198  93.607  1.00 76.68  ? 126 ARG B CA  1 
ATOM   4413 C  C   . ARG B 1 126 ? 125.881 100.506 93.457  1.00 76.68  ? 126 ARG B C   1 
ATOM   4414 O  O   . ARG B 1 126 ? 124.926 100.587 92.681  1.00 76.68  ? 126 ARG B O   1 
ATOM   4415 C  CB  . ARG B 1 126 ? 127.124 98.725  92.244  1.00 76.68  ? 126 ARG B CB  1 
ATOM   4416 C  CG  . ARG B 1 126 ? 127.904 97.454  92.278  1.00 76.68  ? 126 ARG B CG  1 
ATOM   4417 C  CD  . ARG B 1 126 ? 128.196 96.989  90.882  1.00 76.68  ? 126 ARG B CD  1 
ATOM   4418 N  NE  . ARG B 1 126 ? 128.211 95.536  90.814  1.00 76.68  ? 126 ARG B NE  1 
ATOM   4419 C  CZ  . ARG B 1 126 ? 129.315 94.804  90.871  1.00 76.68  ? 126 ARG B CZ  1 
ATOM   4420 N  NH1 . ARG B 1 126 ? 130.495 95.395  90.990  1.00 76.68  ? 126 ARG B NH1 1 
ATOM   4421 N  NH2 . ARG B 1 126 ? 129.238 93.484  90.808  1.00 76.68  ? 126 ARG B NH2 1 
ATOM   4422 N  N   . VAL B 1 127 ? 126.301 101.522 94.196  1.00 73.76  ? 127 VAL B N   1 
ATOM   4423 C  CA  . VAL B 1 127 ? 125.754 102.857 94.028  1.00 73.76  ? 127 VAL B CA  1 
ATOM   4424 C  C   . VAL B 1 127 ? 126.895 103.826 93.776  1.00 73.76  ? 127 VAL B C   1 
ATOM   4425 O  O   . VAL B 1 127 ? 128.043 103.582 94.153  1.00 73.76  ? 127 VAL B O   1 
ATOM   4426 C  CB  . VAL B 1 127 ? 124.908 103.315 95.234  1.00 73.76  ? 127 VAL B CB  1 
ATOM   4427 C  CG1 . VAL B 1 127 ? 123.687 102.444 95.382  1.00 73.76  ? 127 VAL B CG1 1 
ATOM   4428 C  CG2 . VAL B 1 127 ? 125.712 103.273 96.489  1.00 73.76  ? 127 VAL B CG2 1 
ATOM   4429 N  N   . THR B 1 128 ? 126.568 104.923 93.111  1.00 74.07  ? 128 THR B N   1 
ATOM   4430 C  CA  . THR B 1 128 ? 127.499 106.003 92.842  1.00 74.07  ? 128 THR B CA  1 
ATOM   4431 C  C   . THR B 1 128 ? 126.834 107.301 93.255  1.00 74.07  ? 128 THR B C   1 
ATOM   4432 O  O   . THR B 1 128 ? 125.681 107.550 92.902  1.00 74.07  ? 128 THR B O   1 
ATOM   4433 C  CB  . THR B 1 128 ? 127.885 106.048 91.361  1.00 74.07  ? 128 THR B CB  1 
ATOM   4434 O  OG1 . THR B 1 128 ? 128.462 104.796 90.980  1.00 74.07  ? 128 THR B OG1 1 
ATOM   4435 C  CG2 . THR B 1 128 ? 128.884 107.142 91.095  1.00 74.07  ? 128 THR B CG2 1 
ATOM   4436 N  N   . LYS B 1 129 ? 127.545 108.116 94.019  1.00 72.75  ? 129 LYS B N   1 
ATOM   4437 C  CA  . LYS B 1 129 ? 127.013 109.397 94.437  1.00 72.75  ? 129 LYS B CA  1 
ATOM   4438 C  C   . LYS B 1 129 ? 128.108 110.439 94.343  1.00 72.75  ? 129 LYS B C   1 
ATOM   4439 O  O   . LYS B 1 129 ? 129.275 110.153 94.604  1.00 72.75  ? 129 LYS B O   1 
ATOM   4440 C  CB  . LYS B 1 129 ? 126.461 109.336 95.860  1.00 72.75  ? 129 LYS B CB  1 
ATOM   4441 C  CG  . LYS B 1 129 ? 125.602 110.512 96.232  1.00 72.75  ? 129 LYS B CG  1 
ATOM   4442 C  CD  . LYS B 1 129 ? 125.064 110.388 97.622  1.00 72.75  ? 129 LYS B CD  1 
ATOM   4443 C  CE  . LYS B 1 129 ? 124.558 111.716 98.110  1.00 72.75  ? 129 LYS B CE  1 
ATOM   4444 N  NZ  . LYS B 1 129 ? 123.888 111.580 99.416  1.00 72.75  ? 129 LYS B NZ  1 
ATOM   4445 N  N   . HIS B 1 130 ? 127.730 111.643 93.942  1.00 73.57  ? 130 HIS B N   1 
ATOM   4446 C  CA  . HIS B 1 130 ? 128.614 112.794 94.038  1.00 73.57  ? 130 HIS B CA  1 
ATOM   4447 C  C   . HIS B 1 130 ? 128.459 113.395 95.424  1.00 73.57  ? 130 HIS B C   1 
ATOM   4448 O  O   . HIS B 1 130 ? 127.466 114.067 95.707  1.00 73.57  ? 130 HIS B O   1 
ATOM   4449 C  CB  . HIS B 1 130 ? 128.293 113.817 92.958  1.00 73.57  ? 130 HIS B CB  1 
ATOM   4450 C  CG  . HIS B 1 130 ? 128.884 113.486 91.630  1.00 73.57  ? 130 HIS B CG  1 
ATOM   4451 N  ND1 . HIS B 1 130 ? 128.170 112.860 90.635  1.00 73.57  ? 130 HIS B ND1 1 
ATOM   4452 C  CD2 . HIS B 1 130 ? 130.122 113.695 91.131  1.00 73.57  ? 130 HIS B CD2 1 
ATOM   4453 C  CE1 . HIS B 1 130 ? 128.943 112.696 89.580  1.00 73.57  ? 130 HIS B CE1 1 
ATOM   4454 N  NE2 . HIS B 1 130 ? 130.133 113.195 89.855  1.00 73.57  ? 130 HIS B NE2 1 
ATOM   4455 N  N   . VAL B 1 131 ? 129.429 113.141 96.287  1.00 71.11  ? 131 VAL B N   1 
ATOM   4456 C  CA  . VAL B 1 131 ? 129.396 113.605 97.663  1.00 71.11  ? 131 VAL B CA  1 
ATOM   4457 C  C   . VAL B 1 131 ? 130.460 114.669 97.845  1.00 71.11  ? 131 VAL B C   1 
ATOM   4458 O  O   . VAL B 1 131 ? 131.506 114.644 97.195  1.00 71.11  ? 131 VAL B O   1 
ATOM   4459 C  CB  . VAL B 1 131 ? 129.603 112.450 98.662  1.00 71.11  ? 131 VAL B CB  1 
ATOM   4460 C  CG1 . VAL B 1 131 ? 128.328 111.694 98.854  1.00 71.11  ? 131 VAL B CG1 1 
ATOM   4461 C  CG2 . VAL B 1 131 ? 130.663 111.514 98.150  1.00 71.11  ? 131 VAL B CG2 1 
ATOM   4462 N  N   . THR B 1 132 ? 130.188 115.607 98.740  1.00 70.83  ? 132 THR B N   1 
ATOM   4463 C  CA  . THR B 1 132 ? 131.108 116.688 99.048  1.00 70.83  ? 132 THR B CA  1 
ATOM   4464 C  C   . THR B 1 132 ? 131.878 116.351 100.310 1.00 70.83  ? 132 THR B C   1 
ATOM   4465 O  O   . THR B 1 132 ? 131.283 115.951 101.313 1.00 70.83  ? 132 THR B O   1 
ATOM   4466 C  CB  . THR B 1 132 ? 130.359 118.000 99.239  1.00 70.83  ? 132 THR B CB  1 
ATOM   4467 O  OG1 . THR B 1 132 ? 129.365 118.118 98.223  1.00 70.83  ? 132 THR B OG1 1 
ATOM   4468 C  CG2 . THR B 1 132 ? 131.302 119.161 99.137  1.00 70.83  ? 132 THR B CG2 1 
ATOM   4469 N  N   . LEU B 1 133 ? 133.193 116.503 100.254 1.00 71.99  ? 133 LEU B N   1 
ATOM   4470 C  CA  . LEU B 1 133 ? 134.009 116.313 101.439 1.00 71.99  ? 133 LEU B CA  1 
ATOM   4471 C  C   . LEU B 1 133 ? 133.734 117.428 102.430 1.00 71.99  ? 133 LEU B C   1 
ATOM   4472 O  O   . LEU B 1 133 ? 133.475 118.567 102.038 1.00 71.99  ? 133 LEU B O   1 
ATOM   4473 C  CB  . LEU B 1 133 ? 135.486 116.289 101.066 1.00 71.99  ? 133 LEU B CB  1 
ATOM   4474 C  CG  . LEU B 1 133 ? 136.434 115.702 102.102 1.00 71.99  ? 133 LEU B CG  1 
ATOM   4475 C  CD1 . LEU B 1 133 ? 136.407 114.205 102.047 1.00 71.99  ? 133 LEU B CD1 1 
ATOM   4476 C  CD2 . LEU B 1 133 ? 137.824 116.211 101.873 1.00 71.99  ? 133 LEU B CD2 1 
ATOM   4477 N  N   . ALA B 1 134 ? 133.733 117.080 103.709 1.00 71.99  ? 134 ALA B N   1 
ATOM   4478 C  CA  . ALA B 1 134 ? 133.680 118.083 104.756 1.00 71.99  ? 134 ALA B CA  1 
ATOM   4479 C  C   . ALA B 1 134 ? 134.913 118.969 104.649 1.00 71.99  ? 134 ALA B C   1 
ATOM   4480 O  O   . ALA B 1 134 ? 136.024 118.450 104.491 1.00 71.99  ? 134 ALA B O   1 
ATOM   4481 C  CB  . ALA B 1 134 ? 133.612 117.426 106.130 1.00 71.99  ? 134 ALA B CB  1 
ATOM   4482 N  N   . PRO B 1 135 ? 134.759 120.290 104.702 1.00 76.10  ? 135 PRO B N   1 
ATOM   4483 C  CA  . PRO B 1 135 ? 135.811 121.191 104.216 1.00 76.10  ? 135 PRO B CA  1 
ATOM   4484 C  C   . PRO B 1 135 ? 137.065 121.199 105.073 1.00 76.10  ? 135 PRO B C   1 
ATOM   4485 O  O   . PRO B 1 135 ? 137.022 121.467 106.274 1.00 76.10  ? 135 PRO B O   1 
ATOM   4486 C  CB  . PRO B 1 135 ? 135.122 122.557 104.223 1.00 76.10  ? 135 PRO B CB  1 
ATOM   4487 C  CG  . PRO B 1 135 ? 133.679 122.260 104.225 1.00 76.10  ? 135 PRO B CG  1 
ATOM   4488 C  CD  . PRO B 1 135 ? 133.519 121.016 105.002 1.00 76.10  ? 135 PRO B CD  1 
ATOM   4489 N  N   . GLU B 1 136 ? 138.188 120.871 104.437 1.00 82.69  ? 136 GLU B N   1 
ATOM   4490 C  CA  . GLU B 1 136 ? 139.484 121.001 105.084 1.00 82.69  ? 136 GLU B CA  1 
ATOM   4491 C  C   . GLU B 1 136 ? 139.943 122.446 105.100 1.00 82.69  ? 136 GLU B C   1 
ATOM   4492 O  O   . GLU B 1 136 ? 140.837 122.807 105.873 1.00 82.69  ? 136 GLU B O   1 
ATOM   4493 C  CB  . GLU B 1 136 ? 140.515 120.131 104.371 1.00 82.69  ? 136 GLU B CB  1 
ATOM   4494 C  CG  . GLU B 1 136 ? 140.265 118.649 104.505 1.00 82.69  ? 136 GLU B CG  1 
ATOM   4495 C  CD  . GLU B 1 136 ? 140.484 118.154 105.918 1.00 82.69  ? 136 GLU B CD  1 
ATOM   4496 O  OE1 . GLU B 1 136 ? 139.594 117.462 106.453 1.00 82.69  ? 136 GLU B OE1 1 
ATOM   4497 O  OE2 . GLU B 1 136 ? 141.545 118.459 106.497 1.00 82.69  ? 136 GLU B OE2 1 
ATOM   4498 N  N   . ALA B 1 137 ? 139.346 123.273 104.254 1.00 82.39  ? 137 ALA B N   1 
ATOM   4499 C  CA  . ALA B 1 137 ? 139.715 124.672 104.162 1.00 82.39  ? 137 ALA B CA  1 
ATOM   4500 C  C   . ALA B 1 137 ? 139.233 125.436 105.385 1.00 82.39  ? 137 ALA B C   1 
ATOM   4501 O  O   . ALA B 1 137 ? 138.064 125.355 105.767 1.00 82.39  ? 137 ALA B O   1 
ATOM   4502 C  CB  . ALA B 1 137 ? 139.120 125.270 102.894 1.00 82.39  ? 137 ALA B CB  1 
ATOM   4503 N  N   . SER B 1 138 ? 140.143 126.178 106.005 1.00 84.79  ? 138 SER B N   1 
ATOM   4504 C  CA  . SER B 1 138 ? 139.796 127.031 107.132 1.00 84.79  ? 138 SER B CA  1 
ATOM   4505 C  C   . SER B 1 138 ? 139.480 128.435 106.651 1.00 84.79  ? 138 SER B C   1 
ATOM   4506 O  O   . SER B 1 138 ? 140.378 129.279 106.571 1.00 84.79  ? 138 SER B O   1 
ATOM   4507 C  CB  . SER B 1 138 ? 140.937 127.068 108.143 1.00 84.79  ? 138 SER B CB  1 
ATOM   4508 O  OG  . SER B 1 138 ? 140.774 128.149 109.041 1.00 84.79  ? 138 SER B OG  1 
ATOM   4509 N  N   . GLY B 1 139 ? 138.213 128.700 106.344 1.00 81.32  ? 139 GLY B N   1 
ATOM   4510 C  CA  . GLY B 1 139 ? 137.858 129.935 105.679 1.00 81.32  ? 139 GLY B CA  1 
ATOM   4511 C  C   . GLY B 1 139 ? 137.854 131.178 106.535 1.00 81.32  ? 139 GLY B C   1 
ATOM   4512 O  O   . GLY B 1 139 ? 136.828 131.848 106.629 1.00 81.32  ? 139 GLY B O   1 
ATOM   4513 N  N   . ALA B 1 140 ? 138.979 131.503 107.157 1.00 82.33  ? 140 ALA B N   1 
ATOM   4514 C  CA  . ALA B 1 140 ? 139.108 132.748 107.889 1.00 82.33  ? 140 ALA B CA  1 
ATOM   4515 C  C   . ALA B 1 140 ? 139.074 133.925 106.913 1.00 82.33  ? 140 ALA B C   1 
ATOM   4516 O  O   . ALA B 1 140 ? 139.526 133.798 105.774 1.00 82.33  ? 140 ALA B O   1 
ATOM   4517 C  CB  . ALA B 1 140 ? 140.412 132.746 108.683 1.00 82.33  ? 140 ALA B CB  1 
ATOM   4518 N  N   . PRO B 1 141 ? 138.552 135.091 107.327 1.00 79.67  ? 141 PRO B N   1 
ATOM   4519 C  CA  . PRO B 1 141 ? 138.103 135.567 108.635 1.00 79.67  ? 141 PRO B CA  1 
ATOM   4520 C  C   . PRO B 1 141 ? 136.638 135.335 108.952 1.00 79.67  ? 141 PRO B C   1 
ATOM   4521 O  O   . PRO B 1 141 ? 136.200 135.727 110.026 1.00 79.67  ? 141 PRO B O   1 
ATOM   4522 C  CB  . PRO B 1 141 ? 138.373 137.055 108.542 1.00 79.67  ? 141 PRO B CB  1 
ATOM   4523 C  CG  . PRO B 1 141 ? 138.053 137.361 107.136 1.00 79.67  ? 141 PRO B CG  1 
ATOM   4524 C  CD  . PRO B 1 141 ? 138.460 136.165 106.326 1.00 79.67  ? 141 PRO B CD  1 
ATOM   4525 N  N   . PHE B 1 142 ? 135.890 134.718 108.049 1.00 77.51  ? 142 PHE B N   1 
ATOM   4526 C  CA  . PHE B 1 142 ? 134.463 134.595 108.265 1.00 77.51  ? 142 PHE B CA  1 
ATOM   4527 C  C   . PHE B 1 142 ? 134.155 133.453 109.220 1.00 77.51  ? 142 PHE B C   1 
ATOM   4528 O  O   . PHE B 1 142 ? 134.942 132.525 109.398 1.00 77.51  ? 142 PHE B O   1 
ATOM   4529 C  CB  . PHE B 1 142 ? 133.735 134.372 106.945 1.00 77.51  ? 142 PHE B CB  1 
ATOM   4530 C  CG  . PHE B 1 142 ? 134.131 135.329 105.870 1.00 77.51  ? 142 PHE B CG  1 
ATOM   4531 C  CD1 . PHE B 1 142 ? 133.818 136.667 105.970 1.00 77.51  ? 142 PHE B CD1 1 
ATOM   4532 C  CD2 . PHE B 1 142 ? 134.813 134.889 104.755 1.00 77.51  ? 142 PHE B CD2 1 
ATOM   4533 C  CE1 . PHE B 1 142 ? 134.180 137.545 104.982 1.00 77.51  ? 142 PHE B CE1 1 
ATOM   4534 C  CE2 . PHE B 1 142 ? 135.178 135.766 103.766 1.00 77.51  ? 142 PHE B CE2 1 
ATOM   4535 C  CZ  . PHE B 1 142 ? 134.860 137.095 103.881 1.00 77.51  ? 142 PHE B CZ  1 
ATOM   4536 N  N   . ARG B 1 143 ? 132.995 133.543 109.852 1.00 75.79  ? 143 ARG B N   1 
ATOM   4537 C  CA  . ARG B 1 143 ? 132.416 132.448 110.607 1.00 75.79  ? 143 ARG B CA  1 
ATOM   4538 C  C   . ARG B 1 143 ? 131.302 131.847 109.772 1.00 75.79  ? 143 ARG B C   1 
ATOM   4539 O  O   . ARG B 1 143 ? 130.728 132.520 108.918 1.00 75.79  ? 143 ARG B O   1 
ATOM   4540 C  CB  . ARG B 1 143 ? 131.879 132.924 111.950 1.00 75.79  ? 143 ARG B CB  1 
ATOM   4541 C  CG  . ARG B 1 143 ? 132.632 134.100 112.511 1.00 75.79  ? 143 ARG B CG  1 
ATOM   4542 C  CD  . ARG B 1 143 ? 132.497 134.145 113.999 1.00 75.79  ? 143 ARG B CD  1 
ATOM   4543 N  NE  . ARG B 1 143 ? 132.901 132.878 114.586 1.00 75.79  ? 143 ARG B NE  1 
ATOM   4544 C  CZ  . ARG B 1 143 ? 132.393 132.384 115.706 1.00 75.79  ? 143 ARG B CZ  1 
ATOM   4545 N  NH1 . ARG B 1 143 ? 131.457 133.055 116.362 1.00 75.79  ? 143 ARG B NH1 1 
ATOM   4546 N  NH2 . ARG B 1 143 ? 132.817 131.218 116.169 1.00 75.79  ? 143 ARG B NH2 1 
ATOM   4547 N  N   . TYR B 1 144 ? 131.000 130.582 110.003 1.00 73.59  ? 144 TYR B N   1 
ATOM   4548 C  CA  . TYR B 1 144 ? 130.149 129.839 109.093 1.00 73.59  ? 144 TYR B CA  1 
ATOM   4549 C  C   . TYR B 1 144 ? 128.957 129.263 109.829 1.00 73.59  ? 144 TYR B C   1 
ATOM   4550 O  O   . TYR B 1 144 ? 129.099 128.693 110.910 1.00 73.59  ? 144 TYR B O   1 
ATOM   4551 C  CB  . TYR B 1 144 ? 130.950 128.747 108.392 1.00 73.59  ? 144 TYR B CB  1 
ATOM   4552 C  CG  . TYR B 1 144 ? 132.001 129.352 107.507 1.00 73.59  ? 144 TYR B CG  1 
ATOM   4553 C  CD1 . TYR B 1 144 ? 131.689 129.779 106.231 1.00 73.59  ? 144 TYR B CD1 1 
ATOM   4554 C  CD2 . TYR B 1 144 ? 133.289 129.553 107.967 1.00 73.59  ? 144 TYR B CD2 1 
ATOM   4555 C  CE1 . TYR B 1 144 ? 132.631 130.360 105.438 1.00 73.59  ? 144 TYR B CE1 1 
ATOM   4556 C  CE2 . TYR B 1 144 ? 134.230 130.134 107.178 1.00 73.59  ? 144 TYR B CE2 1 
ATOM   4557 C  CZ  . TYR B 1 144 ? 133.897 130.534 105.916 1.00 73.59  ? 144 TYR B CZ  1 
ATOM   4558 O  OH  . TYR B 1 144 ? 134.839 131.115 105.117 1.00 73.59  ? 144 TYR B OH  1 
ATOM   4559 N  N   . GLY B 1 145 ? 127.782 129.442 109.244 1.00 71.94  ? 145 GLY B N   1 
ATOM   4560 C  CA  . GLY B 1 145 ? 126.563 128.933 109.828 1.00 71.94  ? 145 GLY B CA  1 
ATOM   4561 C  C   . GLY B 1 145 ? 125.639 128.437 108.741 1.00 71.94  ? 145 GLY B C   1 
ATOM   4562 O  O   . GLY B 1 145 ? 125.904 128.597 107.551 1.00 71.94  ? 145 GLY B O   1 
ATOM   4563 N  N   . VAL B 1 146 ? 124.562 127.799 109.171 1.00 70.33  ? 146 VAL B N   1 
ATOM   4564 C  CA  . VAL B 1 146 ? 123.528 127.292 108.284 1.00 70.33  ? 146 VAL B CA  1 
ATOM   4565 C  C   . VAL B 1 146 ? 122.191 127.756 108.831 1.00 70.33  ? 146 VAL B C   1 
ATOM   4566 O  O   . VAL B 1 146 ? 121.928 127.621 110.027 1.00 70.33  ? 146 VAL B O   1 
ATOM   4567 C  CB  . VAL B 1 146 ? 123.567 125.752 108.177 1.00 70.33  ? 146 VAL B CB  1 
ATOM   4568 C  CG1 . VAL B 1 146 ? 122.401 125.226 107.378 1.00 70.33  ? 146 VAL B CG1 1 
ATOM   4569 C  CG2 . VAL B 1 146 ? 124.857 125.273 107.566 1.00 70.33  ? 146 VAL B CG2 1 
ATOM   4570 N  N   . SER B 1 147 ? 121.358 128.321 107.971 1.00 72.34  ? 147 SER B N   1 
ATOM   4571 C  CA  . SER B 1 147 ? 119.984 128.597 108.341 1.00 72.34  ? 147 SER B CA  1 
ATOM   4572 C  C   . SER B 1 147 ? 119.129 127.364 108.102 1.00 72.34  ? 147 SER B C   1 
ATOM   4573 O  O   . SER B 1 147 ? 119.300 126.658 107.111 1.00 72.34  ? 147 SER B O   1 
ATOM   4574 C  CB  . SER B 1 147 ? 119.425 129.769 107.548 1.00 72.34  ? 147 SER B CB  1 
ATOM   4575 O  OG  . SER B 1 147 ? 118.017 129.750 107.575 1.00 72.34  ? 147 SER B OG  1 
ATOM   4576 N  N   . LEU B 1 148 ? 118.190 127.116 109.012 1.00 70.73  ? 148 LEU B N   1 
ATOM   4577 C  CA  . LEU B 1 148 ? 117.287 125.984 108.856 1.00 70.73  ? 148 LEU B CA  1 
ATOM   4578 C  C   . LEU B 1 148 ? 116.244 126.205 107.772 1.00 70.73  ? 148 LEU B C   1 
ATOM   4579 O  O   . LEU B 1 148 ? 115.510 125.271 107.444 1.00 70.73  ? 148 LEU B O   1 
ATOM   4580 C  CB  . LEU B 1 148 ? 116.592 125.679 110.175 1.00 70.73  ? 148 LEU B CB  1 
ATOM   4581 C  CG  . LEU B 1 148 ? 117.393 124.979 111.264 1.00 70.73  ? 148 LEU B CG  1 
ATOM   4582 C  CD1 . LEU B 1 148 ? 116.467 124.514 112.357 1.00 70.73  ? 148 LEU B CD1 1 
ATOM   4583 C  CD2 . LEU B 1 148 ? 118.160 123.816 110.698 1.00 70.73  ? 148 LEU B CD2 1 
ATOM   4584 N  N   . TYR B 1 149 ? 116.159 127.414 107.217 1.00 74.63  ? 149 TYR B N   1 
ATOM   4585 C  CA  . TYR B 1 149 ? 115.351 127.665 106.036 1.00 74.63  ? 149 TYR B CA  1 
ATOM   4586 C  C   . TYR B 1 149 ? 115.899 126.942 104.810 1.00 74.63  ? 149 TYR B C   1 
ATOM   4587 O  O   . TYR B 1 149 ? 115.145 126.689 103.865 1.00 74.63  ? 149 TYR B O   1 
ATOM   4588 C  CB  . TYR B 1 149 ? 115.270 129.174 105.803 1.00 74.63  ? 149 TYR B CB  1 
ATOM   4589 C  CG  . TYR B 1 149 ? 114.654 129.585 104.500 1.00 74.63  ? 149 TYR B CG  1 
ATOM   4590 C  CD1 . TYR B 1 149 ? 113.291 129.489 104.298 1.00 74.63  ? 149 TYR B CD1 1 
ATOM   4591 C  CD2 . TYR B 1 149 ? 115.439 130.042 103.461 1.00 74.63  ? 149 TYR B CD2 1 
ATOM   4592 C  CE1 . TYR B 1 149 ? 112.728 129.851 103.106 1.00 74.63  ? 149 TYR B CE1 1 
ATOM   4593 C  CE2 . TYR B 1 149 ? 114.886 130.401 102.269 1.00 74.63  ? 149 TYR B CE2 1 
ATOM   4594 C  CZ  . TYR B 1 149 ? 113.531 130.307 102.095 1.00 74.63  ? 149 TYR B CZ  1 
ATOM   4595 O  OH  . TYR B 1 149 ? 112.972 130.673 100.899 1.00 74.63  ? 149 TYR B OH  1 
ATOM   4596 N  N   . SER B 1 150 ? 117.189 126.585 104.818 1.00 73.66  ? 150 SER B N   1 
ATOM   4597 C  CA  . SER B 1 150 ? 117.783 125.826 103.721 1.00 73.66  ? 150 SER B CA  1 
ATOM   4598 C  C   . SER B 1 150 ? 117.125 124.468 103.562 1.00 73.66  ? 150 SER B C   1 
ATOM   4599 O  O   . SER B 1 150 ? 117.026 123.943 102.452 1.00 73.66  ? 150 SER B O   1 
ATOM   4600 C  CB  . SER B 1 150 ? 119.276 125.646 103.961 1.00 73.66  ? 150 SER B CB  1 
ATOM   4601 O  OG  . SER B 1 150 ? 119.931 126.888 104.022 1.00 73.66  ? 150 SER B OG  1 
ATOM   4602 N  N   . TYR B 1 151 ? 116.660 123.890 104.659 1.00 73.75  ? 151 TYR B N   1 
ATOM   4603 C  CA  . TYR B 1 151 ? 115.871 122.667 104.620 1.00 73.75  ? 151 TYR B CA  1 
ATOM   4604 C  C   . TYR B 1 151 ? 114.388 123.002 104.745 1.00 73.75  ? 151 TYR B C   1 
ATOM   4605 O  O   . TYR B 1 151 ? 113.761 122.714 105.746 1.00 73.75  ? 151 TYR B O   1 
ATOM   4606 C  CB  . TYR B 1 151 ? 116.313 121.731 105.734 1.00 73.75  ? 151 TYR B CB  1 
ATOM   4607 C  CG  . TYR B 1 151 ? 117.806 121.622 105.912 1.00 73.75  ? 151 TYR B CG  1 
ATOM   4608 C  CD1 . TYR B 1 151 ? 118.630 121.293 104.848 1.00 73.75  ? 151 TYR B CD1 1 
ATOM   4609 C  CD2 . TYR B 1 151 ? 118.389 121.833 107.146 1.00 73.75  ? 151 TYR B CD2 1 
ATOM   4610 C  CE1 . TYR B 1 151 ? 119.989 121.185 105.010 1.00 73.75  ? 151 TYR B CE1 1 
ATOM   4611 C  CE2 . TYR B 1 151 ? 119.746 121.725 107.316 1.00 73.75  ? 151 TYR B CE2 1 
ATOM   4612 C  CZ  . TYR B 1 151 ? 120.538 121.400 106.245 1.00 73.75  ? 151 TYR B CZ  1 
ATOM   4613 O  OH  . TYR B 1 151 ? 121.893 121.290 106.409 1.00 73.75  ? 151 TYR B OH  1 
ATOM   4614 N  N   . MET B 1 152 ? 113.828 123.633 103.712 1.00 77.60  ? 152 MET B N   1 
ATOM   4615 C  CA  . MET B 1 152 ? 112.483 124.187 103.845 1.00 77.60  ? 152 MET B CA  1 
ATOM   4616 C  C   . MET B 1 152 ? 111.424 123.096 103.822 1.00 77.60  ? 152 MET B C   1 
ATOM   4617 O  O   . MET B 1 152 ? 110.662 122.937 104.780 1.00 77.60  ? 152 MET B O   1 
ATOM   4618 C  CB  . MET B 1 152 ? 112.216 125.212 102.751 1.00 77.60  ? 152 MET B CB  1 
ATOM   4619 C  CG  . MET B 1 152 ? 110.772 125.646 102.658 1.00 77.60  ? 152 MET B CG  1 
ATOM   4620 S  SD  . MET B 1 152 ? 110.480 126.775 101.299 1.00 77.60  ? 152 MET B SD  1 
ATOM   4621 C  CE  . MET B 1 152 ? 108.718 126.606 101.098 1.00 77.60  ? 152 MET B CE  1 
ATOM   4622 N  N   . SER B 1 153 ? 111.352 122.335 102.740 1.00 76.77  ? 153 SER B N   1 
ATOM   4623 C  CA  . SER B 1 153 ? 110.384 121.253 102.689 1.00 76.77  ? 153 SER B CA  1 
ATOM   4624 C  C   . SER B 1 153 ? 110.922 119.971 103.291 1.00 76.77  ? 153 SER B C   1 
ATOM   4625 O  O   . SER B 1 153 ? 110.142 119.053 103.555 1.00 76.77  ? 153 SER B O   1 
ATOM   4626 C  CB  . SER B 1 153 ? 109.942 121.003 101.251 1.00 76.77  ? 153 SER B CB  1 
ATOM   4627 O  OG  . SER B 1 153 ? 109.278 122.133 100.728 1.00 76.77  ? 153 SER B OG  1 
ATOM   4628 N  N   . ASP B 1 154 ? 112.231 119.898 103.521 1.00 78.33  ? 154 ASP B N   1 
ATOM   4629 C  CA  . ASP B 1 154 ? 112.819 118.710 104.123 1.00 78.33  ? 154 ASP B CA  1 
ATOM   4630 C  C   . ASP B 1 154 ? 112.512 118.636 105.608 1.00 78.33  ? 154 ASP B C   1 
ATOM   4631 O  O   . ASP B 1 154 ? 112.277 117.549 106.144 1.00 78.33  ? 154 ASP B O   1 
ATOM   4632 C  CB  . ASP B 1 154 ? 114.323 118.703 103.887 1.00 78.33  ? 154 ASP B CB  1 
ATOM   4633 C  CG  . ASP B 1 154 ? 114.688 118.272 102.490 1.00 78.33  ? 154 ASP B CG  1 
ATOM   4634 O  OD1 . ASP B 1 154 ? 113.877 117.575 101.856 1.00 78.33  ? 154 ASP B OD1 1 
ATOM   4635 O  OD2 . ASP B 1 154 ? 115.786 118.626 102.022 1.00 78.33  ? 154 ASP B OD2 1 
ATOM   4636 N  N   . TYR B 1 155 ? 112.510 119.778 106.288 1.00 77.92  ? 155 TYR B N   1 
ATOM   4637 C  CA  . TYR B 1 155 ? 112.215 119.817 107.711 1.00 77.92  ? 155 TYR B CA  1 
ATOM   4638 C  C   . TYR B 1 155 ? 110.743 119.525 107.944 1.00 77.92  ? 155 TYR B C   1 
ATOM   4639 O  O   . TYR B 1 155 ? 109.872 120.243 107.448 1.00 77.92  ? 155 TYR B O   1 
ATOM   4640 C  CB  . TYR B 1 155 ? 112.581 121.179 108.284 1.00 77.92  ? 155 TYR B CB  1 
ATOM   4641 C  CG  . TYR B 1 155 ? 112.553 121.261 109.780 1.00 77.92  ? 155 TYR B CG  1 
ATOM   4642 C  CD1 . TYR B 1 155 ? 111.419 121.697 110.444 1.00 77.92  ? 155 TYR B CD1 1 
ATOM   4643 C  CD2 . TYR B 1 155 ? 113.662 120.918 110.529 1.00 77.92  ? 155 TYR B CD2 1 
ATOM   4644 C  CE1 . TYR B 1 155 ? 111.385 121.772 111.803 1.00 77.92  ? 155 TYR B CE1 1 
ATOM   4645 C  CE2 . TYR B 1 155 ? 113.639 120.994 111.895 1.00 77.92  ? 155 TYR B CE2 1 
ATOM   4646 C  CZ  . TYR B 1 155 ? 112.495 121.421 112.526 1.00 77.92  ? 155 TYR B CZ  1 
ATOM   4647 O  OH  . TYR B 1 155 ? 112.454 121.504 113.894 1.00 77.92  ? 155 TYR B OH  1 
ATOM   4648 N  N   . GLY B 1 156 ? 110.466 118.479 108.709 1.00 77.26  ? 156 GLY B N   1 
ATOM   4649 C  CA  . GLY B 1 156 ? 109.117 118.057 108.978 1.00 77.26  ? 156 GLY B CA  1 
ATOM   4650 C  C   . GLY B 1 156 ? 108.645 116.906 108.128 1.00 77.26  ? 156 GLY B C   1 
ATOM   4651 O  O   . GLY B 1 156 ? 107.662 116.256 108.489 1.00 77.26  ? 156 GLY B O   1 
ATOM   4652 N  N   . THR B 1 157 ? 109.307 116.638 107.009 1.00 75.88  ? 157 THR B N   1 
ATOM   4653 C  CA  . THR B 1 157 ? 108.984 115.500 106.166 1.00 75.88  ? 157 THR B CA  1 
ATOM   4654 C  C   . THR B 1 157 ? 110.066 114.434 106.190 1.00 75.88  ? 157 THR B C   1 
ATOM   4655 O  O   . THR B 1 157 ? 109.763 113.259 106.392 1.00 75.88  ? 157 THR B O   1 
ATOM   4656 C  CB  . THR B 1 157 ? 108.739 115.956 104.724 1.00 75.88  ? 157 THR B CB  1 
ATOM   4657 O  OG1 . THR B 1 157 ? 109.911 116.597 104.220 1.00 75.88  ? 157 THR B OG1 1 
ATOM   4658 C  CG2 . THR B 1 157 ? 107.599 116.928 104.671 1.00 75.88  ? 157 THR B CG2 1 
ATOM   4659 N  N   . VAL B 1 158 ? 111.326 114.809 105.984 1.00 75.78  ? 158 VAL B N   1 
ATOM   4660 C  CA  . VAL B 1 158 ? 112.437 113.866 106.030 1.00 75.78  ? 158 VAL B CA  1 
ATOM   4661 C  C   . VAL B 1 158 ? 113.423 114.176 107.138 1.00 75.78  ? 158 VAL B C   1 
ATOM   4662 O  O   . VAL B 1 158 ? 114.396 113.432 107.305 1.00 75.78  ? 158 VAL B O   1 
ATOM   4663 C  CB  . VAL B 1 158 ? 113.184 113.795 104.682 1.00 75.78  ? 158 VAL B CB  1 
ATOM   4664 C  CG1 . VAL B 1 158 ? 112.232 113.625 103.555 1.00 75.78  ? 158 VAL B CG1 1 
ATOM   4665 C  CG2 . VAL B 1 158 ? 114.011 115.032 104.464 1.00 75.78  ? 158 VAL B CG2 1 
ATOM   4666 N  N   . MET B 1 159 ? 113.206 115.234 107.906 1.00 79.36  ? 159 MET B N   1 
ATOM   4667 C  CA  . MET B 1 159 ? 114.231 115.742 108.797 1.00 79.36  ? 159 MET B CA  1 
ATOM   4668 C  C   . MET B 1 159 ? 113.588 116.327 110.040 1.00 79.36  ? 159 MET B C   1 
ATOM   4669 O  O   . MET B 1 159 ? 112.529 116.950 109.973 1.00 79.36  ? 159 MET B O   1 
ATOM   4670 C  CB  . MET B 1 159 ? 115.070 116.803 108.086 1.00 79.36  ? 159 MET B CB  1 
ATOM   4671 C  CG  . MET B 1 159 ? 116.427 117.033 108.671 1.00 79.36  ? 159 MET B CG  1 
ATOM   4672 S  SD  . MET B 1 159 ? 117.291 118.335 107.789 1.00 79.36  ? 159 MET B SD  1 
ATOM   4673 C  CE  . MET B 1 159 ? 117.214 117.700 106.128 1.00 79.36  ? 159 MET B CE  1 
ATOM   4674 N  N   . ASP B 1 160 ? 114.243 116.124 111.175 1.00 81.31  ? 160 ASP B N   1 
ATOM   4675 C  CA  . ASP B 1 160 ? 113.878 116.765 112.426 1.00 81.31  ? 160 ASP B CA  1 
ATOM   4676 C  C   . ASP B 1 160 ? 115.035 117.639 112.884 1.00 81.31  ? 160 ASP B C   1 
ATOM   4677 O  O   . ASP B 1 160 ? 115.975 117.895 112.134 1.00 81.31  ? 160 ASP B O   1 
ATOM   4678 C  CB  . ASP B 1 160 ? 113.500 115.747 113.502 1.00 81.31  ? 160 ASP B CB  1 
ATOM   4679 C  CG  . ASP B 1 160 ? 114.530 114.668 113.667 1.00 81.31  ? 160 ASP B CG  1 
ATOM   4680 O  OD1 . ASP B 1 160 ? 115.330 114.477 112.742 1.00 81.31  ? 160 ASP B OD1 1 
ATOM   4681 O  OD2 . ASP B 1 160 ? 114.548 114.012 114.726 1.00 81.31  ? 160 ASP B OD2 1 
ATOM   4682 N  N   . LEU B 1 161 ? 114.942 118.116 114.125 1.00 77.35  ? 161 LEU B N   1 
ATOM   4683 C  CA  . LEU B 1 161 ? 115.892 119.110 114.612 1.00 77.35  ? 161 LEU B CA  1 
ATOM   4684 C  C   . LEU B 1 161 ? 117.277 118.516 114.830 1.00 77.35  ? 161 LEU B C   1 
ATOM   4685 O  O   . LEU B 1 161 ? 118.285 119.164 114.536 1.00 77.35  ? 161 LEU B O   1 
ATOM   4686 C  CB  . LEU B 1 161 ? 115.372 119.734 115.903 1.00 77.35  ? 161 LEU B CB  1 
ATOM   4687 C  CG  . LEU B 1 161 ? 116.208 120.868 116.484 1.00 77.35  ? 161 LEU B CG  1 
ATOM   4688 C  CD1 . LEU B 1 161 ? 116.304 121.997 115.493 1.00 77.35  ? 161 LEU B CD1 1 
ATOM   4689 C  CD2 . LEU B 1 161 ? 115.622 121.349 117.783 1.00 77.35  ? 161 LEU B CD2 1 
ATOM   4690 N  N   . GLU B 1 162 ? 117.352 117.287 115.337 1.00 79.21  ? 162 GLU B N   1 
ATOM   4691 C  CA  . GLU B 1 162 ? 118.656 116.701 115.626 1.00 79.21  ? 162 GLU B CA  1 
ATOM   4692 C  C   . GLU B 1 162 ? 119.368 116.270 114.354 1.00 79.21  ? 162 GLU B C   1 
ATOM   4693 O  O   . GLU B 1 162 ? 120.597 116.346 114.272 1.00 79.21  ? 162 GLU B O   1 
ATOM   4694 C  CB  . GLU B 1 162 ? 118.510 115.518 116.573 1.00 79.21  ? 162 GLU B CB  1 
ATOM   4695 C  CG  . GLU B 1 162 ? 119.825 115.080 117.177 1.00 79.21  ? 162 GLU B CG  1 
ATOM   4696 C  CD  . GLU B 1 162 ? 119.680 113.905 118.105 1.00 79.21  ? 162 GLU B CD  1 
ATOM   4697 O  OE1 . GLU B 1 162 ? 118.584 113.313 118.144 1.00 79.21  ? 162 GLU B OE1 1 
ATOM   4698 O  OE2 . GLU B 1 162 ? 120.664 113.569 118.795 1.00 79.21  ? 162 GLU B OE2 1 
ATOM   4699 N  N   . THR B 1 163 ? 118.616 115.807 113.355 1.00 77.54  ? 163 THR B N   1 
ATOM   4700 C  CA  . THR B 1 163 ? 119.219 115.448 112.077 1.00 77.54  ? 163 THR B CA  1 
ATOM   4701 C  C   . THR B 1 163 ? 119.741 116.682 111.363 1.00 77.54  ? 163 THR B C   1 
ATOM   4702 O  O   . THR B 1 163 ? 120.800 116.643 110.728 1.00 77.54  ? 163 THR B O   1 
ATOM   4703 C  CB  . THR B 1 163 ? 118.197 114.724 111.206 1.00 77.54  ? 163 THR B CB  1 
ATOM   4704 O  OG1 . THR B 1 163 ? 117.644 113.633 111.944 1.00 77.54  ? 163 THR B OG1 1 
ATOM   4705 C  CG2 . THR B 1 163 ? 118.835 114.173 109.959 1.00 77.54  ? 163 THR B CG2 1 
ATOM   4706 N  N   . ALA B 1 164 ? 119.021 117.795 111.477 1.00 73.03  ? 164 ALA B N   1 
ATOM   4707 C  CA  . ALA B 1 164 ? 119.482 119.039 110.884 1.00 73.03  ? 164 ALA B CA  1 
ATOM   4708 C  C   . ALA B 1 164 ? 120.702 119.570 111.615 1.00 73.03  ? 164 ALA B C   1 
ATOM   4709 O  O   . ALA B 1 164 ? 121.631 120.082 110.988 1.00 73.03  ? 164 ALA B O   1 
ATOM   4710 C  CB  . ALA B 1 164 ? 118.360 120.070 110.895 1.00 73.03  ? 164 ALA B CB  1 
ATOM   4711 N  N   . MET B 1 165 ? 120.730 119.429 112.938 1.00 74.50  ? 165 MET B N   1 
ATOM   4712 C  CA  . MET B 1 165 ? 121.855 119.931 113.717 1.00 74.50  ? 165 MET B CA  1 
ATOM   4713 C  C   . MET B 1 165 ? 123.094 119.076 113.527 1.00 74.50  ? 165 MET B C   1 
ATOM   4714 O  O   . MET B 1 165 ? 124.217 119.577 113.616 1.00 74.50  ? 165 MET B O   1 
ATOM   4715 C  CB  . MET B 1 165 ? 121.479 119.983 115.189 1.00 74.50  ? 165 MET B CB  1 
ATOM   4716 C  CG  . MET B 1 165 ? 120.918 121.295 115.630 1.00 74.50  ? 165 MET B CG  1 
ATOM   4717 S  SD  . MET B 1 165 ? 120.195 121.144 117.254 1.00 74.50  ? 165 MET B SD  1 
ATOM   4718 C  CE  . MET B 1 165 ? 120.485 122.766 117.901 1.00 74.50  ? 165 MET B CE  1 
ATOM   4719 N  N   . ALA B 1 166 ? 122.913 117.778 113.288 1.00 72.86  ? 166 ALA B N   1 
ATOM   4720 C  CA  . ALA B 1 166 ? 124.053 116.902 113.055 1.00 72.86  ? 166 ALA B CA  1 
ATOM   4721 C  C   . ALA B 1 166 ? 124.709 117.205 111.721 1.00 72.86  ? 166 ALA B C   1 
ATOM   4722 O  O   . ALA B 1 166 ? 125.926 117.066 111.568 1.00 72.86  ? 166 ALA B O   1 
ATOM   4723 C  CB  . ALA B 1 166 ? 123.611 115.445 113.109 1.00 72.86  ? 166 ALA B CB  1 
ATOM   4724 N  N   . SER B 1 167 ? 123.915 117.625 110.743 1.00 71.38  ? 167 SER B N   1 
ATOM   4725 C  CA  . SER B 1 167 ? 124.464 117.947 109.437 1.00 71.38  ? 167 SER B CA  1 
ATOM   4726 C  C   . SER B 1 167 ? 125.196 119.276 109.461 1.00 71.38  ? 167 SER B C   1 
ATOM   4727 O  O   . SER B 1 167 ? 126.163 119.460 108.724 1.00 71.38  ? 167 SER B O   1 
ATOM   4728 C  CB  . SER B 1 167 ? 123.354 117.967 108.397 1.00 71.38  ? 167 SER B CB  1 
ATOM   4729 O  OG  . SER B 1 167 ? 122.482 119.048 108.633 1.00 71.38  ? 167 SER B OG  1 
ATOM   4730 N  N   . ILE B 1 168 ? 124.757 120.210 110.302 1.00 71.15  ? 168 ILE B N   1 
ATOM   4731 C  CA  . ILE B 1 168 ? 125.426 121.502 110.401 1.00 71.15  ? 168 ILE B CA  1 
ATOM   4732 C  C   . ILE B 1 168 ? 126.785 121.351 111.071 1.00 71.15  ? 168 ILE B C   1 
ATOM   4733 O  O   . ILE B 1 168 ? 127.774 121.958 110.648 1.00 71.15  ? 168 ILE B O   1 
ATOM   4734 C  CB  . ILE B 1 168 ? 124.523 122.500 111.147 1.00 71.15  ? 168 ILE B CB  1 
ATOM   4735 C  CG1 . ILE B 1 168 ? 123.268 122.775 110.333 1.00 71.15  ? 168 ILE B CG1 1 
ATOM   4736 C  CG2 . ILE B 1 168 ? 125.228 123.804 111.407 1.00 71.15  ? 168 ILE B CG2 1 
ATOM   4737 C  CD1 . ILE B 1 168 ? 122.256 123.607 111.051 1.00 71.15  ? 168 ILE B CD1 1 
ATOM   4738 N  N   . ALA B 1 169 ? 126.867 120.508 112.096 1.00 72.30  ? 169 ALA B N   1 
ATOM   4739 C  CA  . ALA B 1 169 ? 128.126 120.320 112.805 1.00 72.30  ? 169 ALA B CA  1 
ATOM   4740 C  C   . ALA B 1 169 ? 129.117 119.508 111.984 1.00 72.30  ? 169 ALA B C   1 
ATOM   4741 O  O   . ALA B 1 169 ? 130.323 119.554 112.241 1.00 72.30  ? 169 ALA B O   1 
ATOM   4742 C  CB  . ALA B 1 169 ? 127.869 119.646 114.145 1.00 72.30  ? 169 ALA B CB  1 
ATOM   4743 N  N   . ASP B 1 170 ? 128.634 118.754 110.998 1.00 74.21  ? 170 ASP B N   1 
ATOM   4744 C  CA  . ASP B 1 170 ? 129.541 117.989 110.155 1.00 74.21  ? 170 ASP B CA  1 
ATOM   4745 C  C   . ASP B 1 170 ? 130.224 118.876 109.127 1.00 74.21  ? 170 ASP B C   1 
ATOM   4746 O  O   . ASP B 1 170 ? 131.308 118.545 108.640 1.00 74.21  ? 170 ASP B O   1 
ATOM   4747 C  CB  . ASP B 1 170 ? 128.796 116.856 109.464 1.00 74.21  ? 170 ASP B CB  1 
ATOM   4748 C  CG  . ASP B 1 170 ? 129.728 115.777 108.968 1.00 74.21  ? 170 ASP B CG  1 
ATOM   4749 O  OD1 . ASP B 1 170 ? 130.330 115.082 109.808 1.00 74.21  ? 170 ASP B OD1 1 
ATOM   4750 O  OD2 . ASP B 1 170 ? 129.871 115.623 107.740 1.00 74.21  ? 170 ASP B OD2 1 
ATOM   4751 N  N   . LEU B 1 171 ? 129.609 120.006 108.779 1.00 73.90  ? 171 LEU B N   1 
ATOM   4752 C  CA  . LEU B 1 171 ? 130.271 120.960 107.899 1.00 73.90  ? 171 LEU B CA  1 
ATOM   4753 C  C   . LEU B 1 171 ? 131.415 121.670 108.599 1.00 73.90  ? 171 LEU B C   1 
ATOM   4754 O  O   . LEU B 1 171 ? 132.290 122.239 107.941 1.00 73.90  ? 171 LEU B O   1 
ATOM   4755 C  CB  . LEU B 1 171 ? 129.289 122.007 107.383 1.00 73.90  ? 171 LEU B CB  1 
ATOM   4756 C  CG  . LEU B 1 171 ? 128.561 121.796 106.065 1.00 73.90  ? 171 LEU B CG  1 
ATOM   4757 C  CD1 . LEU B 1 171 ? 129.587 121.530 105.000 1.00 73.90  ? 171 LEU B CD1 1 
ATOM   4758 C  CD2 . LEU B 1 171 ? 127.574 120.700 106.117 1.00 73.90  ? 171 LEU B CD2 1 
ATOM   4759 N  N   . GLY B 1 172 ? 131.420 121.669 109.922 1.00 72.80  ? 172 GLY B N   1 
ATOM   4760 C  CA  . GLY B 1 172 ? 132.312 122.513 110.672 1.00 72.80  ? 172 GLY B CA  1 
ATOM   4761 C  C   . GLY B 1 172 ? 131.755 123.880 110.954 1.00 72.80  ? 172 GLY B C   1 
ATOM   4762 O  O   . GLY B 1 172 ? 132.489 124.737 111.451 1.00 72.80  ? 172 GLY B O   1 
ATOM   4763 N  N   . ALA B 1 173 ? 130.490 124.115 110.635 1.00 72.68  ? 173 ALA B N   1 
ATOM   4764 C  CA  . ALA B 1 173 ? 129.850 125.377 110.945 1.00 72.68  ? 173 ALA B CA  1 
ATOM   4765 C  C   . ALA B 1 173 ? 129.595 125.476 112.438 1.00 72.68  ? 173 ALA B C   1 
ATOM   4766 O  O   . ALA B 1 173 ? 129.421 124.469 113.123 1.00 72.68  ? 173 ALA B O   1 
ATOM   4767 C  CB  . ALA B 1 173 ? 128.541 125.508 110.175 1.00 72.68  ? 173 ALA B CB  1 
ATOM   4768 N  N   . THR B 1 174 ? 129.584 126.702 112.947 1.00 73.22  ? 174 THR B N   1 
ATOM   4769 C  CA  . THR B 1 174 ? 129.420 126.928 114.373 1.00 73.22  ? 174 THR B CA  1 
ATOM   4770 C  C   . THR B 1 174 ? 128.126 127.646 114.713 1.00 73.22  ? 174 THR B C   1 
ATOM   4771 O  O   . THR B 1 174 ? 127.769 127.721 115.888 1.00 73.22  ? 174 THR B O   1 
ATOM   4772 C  CB  . THR B 1 174 ? 130.606 127.713 114.927 1.00 73.22  ? 174 THR B CB  1 
ATOM   4773 O  OG1 . THR B 1 174 ? 130.799 128.895 114.149 1.00 73.22  ? 174 THR B OG1 1 
ATOM   4774 C  CG2 . THR B 1 174 ? 131.857 126.879 114.860 1.00 73.22  ? 174 THR B CG2 1 
ATOM   4775 N  N   . GLY B 1 175 ? 127.412 128.163 113.729 1.00 70.58  ? 175 GLY B N   1 
ATOM   4776 C  CA  . GLY B 1 175 ? 126.180 128.883 113.985 1.00 70.58  ? 175 GLY B CA  1 
ATOM   4777 C  C   . GLY B 1 175 ? 124.991 128.181 113.377 1.00 70.58  ? 175 GLY B C   1 
ATOM   4778 O  O   . GLY B 1 175 ? 125.113 127.456 112.396 1.00 70.58  ? 175 GLY B O   1 
ATOM   4779 N  N   . ILE B 1 176 ? 123.829 128.396 113.980 1.00 70.04  ? 176 ILE B N   1 
ATOM   4780 C  CA  . ILE B 1 176 ? 122.570 127.891 113.459 1.00 70.04  ? 176 ILE B CA  1 
ATOM   4781 C  C   . ILE B 1 176 ? 121.549 129.020 113.511 1.00 70.04  ? 176 ILE B C   1 
ATOM   4782 O  O   . ILE B 1 176 ? 121.457 129.744 114.507 1.00 70.04  ? 176 ILE B O   1 
ATOM   4783 C  CB  . ILE B 1 176 ? 122.100 126.633 114.221 1.00 70.04  ? 176 ILE B CB  1 
ATOM   4784 C  CG1 . ILE B 1 176 ? 120.735 126.162 113.730 1.00 70.04  ? 176 ILE B CG1 1 
ATOM   4785 C  CG2 . ILE B 1 176 ? 122.120 126.834 115.726 1.00 70.04  ? 176 ILE B CG2 1 
ATOM   4786 C  CD1 . ILE B 1 176 ? 120.339 124.820 114.243 1.00 70.04  ? 176 ILE B CD1 1 
ATOM   4787 N  N   . GLU B 1 177 ? 120.833 129.211 112.412 1.00 73.86  ? 177 GLU B N   1 
ATOM   4788 C  CA  . GLU B 1 177 ? 119.799 130.221 112.298 1.00 73.86  ? 177 GLU B CA  1 
ATOM   4789 C  C   . GLU B 1 177 ? 118.468 129.527 112.072 1.00 73.86  ? 177 GLU B C   1 
ATOM   4790 O  O   . GLU B 1 177 ? 118.372 128.617 111.250 1.00 73.86  ? 177 GLU B O   1 
ATOM   4791 C  CB  . GLU B 1 177 ? 120.103 131.178 111.151 1.00 73.86  ? 177 GLU B CB  1 
ATOM   4792 C  CG  . GLU B 1 177 ? 118.899 131.890 110.594 1.00 73.86  ? 177 GLU B CG  1 
ATOM   4793 C  CD  . GLU B 1 177 ? 119.250 132.865 109.504 1.00 73.86  ? 177 GLU B CD  1 
ATOM   4794 O  OE1 . GLU B 1 177 ? 120.381 132.794 108.990 1.00 73.86  ? 177 GLU B OE1 1 
ATOM   4795 O  OE2 . GLU B 1 177 ? 118.395 133.705 109.160 1.00 73.86  ? 177 GLU B OE2 1 
ATOM   4796 N  N   . ILE B 1 178 ? 117.448 129.921 112.831 1.00 71.60  ? 178 ILE B N   1 
ATOM   4797 C  CA  . ILE B 1 178 ? 116.119 129.354 112.666 1.00 71.60  ? 178 ILE B CA  1 
ATOM   4798 C  C   . ILE B 1 178 ? 115.135 130.463 112.336 1.00 71.60  ? 178 ILE B C   1 
ATOM   4799 O  O   . ILE B 1 178 ? 115.413 131.648 112.510 1.00 71.60  ? 178 ILE B O   1 
ATOM   4800 C  CB  . ILE B 1 178 ? 115.637 128.574 113.911 1.00 71.60  ? 178 ILE B CB  1 
ATOM   4801 C  CG1 . ILE B 1 178 ? 115.109 129.522 114.981 1.00 71.60  ? 178 ILE B CG1 1 
ATOM   4802 C  CG2 . ILE B 1 178 ? 116.734 127.696 114.473 1.00 71.60  ? 178 ILE B CG2 1 
ATOM   4803 C  CD1 . ILE B 1 178 ? 114.489 128.816 116.149 1.00 71.60  ? 178 ILE B CD1 1 
ATOM   4804 N  N   . LEU B 1 179 ? 113.984 130.062 111.816 1.00 72.52  ? 179 LEU B N   1 
ATOM   4805 C  CA  . LEU B 1 179 ? 112.801 130.905 111.803 1.00 72.52  ? 179 LEU B CA  1 
ATOM   4806 C  C   . LEU B 1 179 ? 111.944 130.492 112.984 1.00 72.52  ? 179 LEU B C   1 
ATOM   4807 O  O   . LEU B 1 179 ? 111.547 129.328 113.081 1.00 72.52  ? 179 LEU B O   1 
ATOM   4808 C  CB  . LEU B 1 179 ? 112.019 130.747 110.503 1.00 72.52  ? 179 LEU B CB  1 
ATOM   4809 C  CG  . LEU B 1 179 ? 112.808 130.763 109.201 1.00 72.52  ? 179 LEU B CG  1 
ATOM   4810 C  CD1 . LEU B 1 179 ? 112.007 130.097 108.112 1.00 72.52  ? 179 LEU B CD1 1 
ATOM   4811 C  CD2 . LEU B 1 179 ? 113.147 132.177 108.817 1.00 72.52  ? 179 LEU B CD2 1 
ATOM   4812 N  N   . GLY B 1 180 ? 111.675 131.437 113.883 1.00 73.13  ? 180 GLY B N   1 
ATOM   4813 C  CA  . GLY B 1 180 ? 111.080 131.083 115.160 1.00 73.13  ? 180 GLY B CA  1 
ATOM   4814 C  C   . GLY B 1 180 ? 109.646 130.619 115.034 1.00 73.13  ? 180 GLY B C   1 
ATOM   4815 O  O   . GLY B 1 180 ? 109.189 129.771 115.798 1.00 73.13  ? 180 GLY B O   1 
ATOM   4816 N  N   . GLU B 1 181 ? 108.936 131.131 114.039 1.00 75.84  ? 181 GLU B N   1 
ATOM   4817 C  CA  . GLU B 1 181 ? 107.538 130.793 113.839 1.00 75.84  ? 181 GLU B CA  1 
ATOM   4818 C  C   . GLU B 1 181 ? 107.381 129.524 113.006 1.00 75.84  ? 181 GLU B C   1 
ATOM   4819 O  O   . GLU B 1 181 ? 106.262 129.143 112.665 1.00 75.84  ? 181 GLU B O   1 
ATOM   4820 C  CB  . GLU B 1 181 ? 106.857 132.020 113.222 1.00 75.84  ? 181 GLU B CB  1 
ATOM   4821 C  CG  . GLU B 1 181 ? 105.369 132.118 113.371 1.00 75.84  ? 181 GLU B CG  1 
ATOM   4822 C  CD  . GLU B 1 181 ? 104.838 133.472 113.002 1.00 75.84  ? 181 GLU B CD  1 
ATOM   4823 O  OE1 . GLU B 1 181 ? 105.648 134.351 112.658 1.00 75.84  ? 181 GLU B OE1 1 
ATOM   4824 O  OE2 . GLU B 1 181 ? 103.609 133.670 113.070 1.00 75.84  ? 181 GLU B OE2 1 
ATOM   4825 N  N   . ALA B 1 182 ? 108.482 128.847 112.696 1.00 72.42  ? 182 ALA B N   1 
ATOM   4826 C  CA  . ALA B 1 182 ? 108.492 127.605 111.938 1.00 72.42  ? 182 ALA B CA  1 
ATOM   4827 C  C   . ALA B 1 182 ? 109.145 126.456 112.684 1.00 72.42  ? 182 ALA B C   1 
ATOM   4828 O  O   . ALA B 1 182 ? 108.694 125.316 112.567 1.00 72.42  ? 182 ALA B O   1 
ATOM   4829 C  CB  . ALA B 1 182 ? 109.228 127.806 110.616 1.00 72.42  ? 182 ALA B CB  1 
ATOM   4830 N  N   . HIS B 1 183 ? 110.203 126.726 113.442 1.00 71.08  ? 183 HIS B N   1 
ATOM   4831 C  CA  . HIS B 1 183 ? 111.030 125.673 114.003 1.00 71.08  ? 183 HIS B CA  1 
ATOM   4832 C  C   . HIS B 1 183 ? 110.909 125.538 115.509 1.00 71.08  ? 183 HIS B C   1 
ATOM   4833 O  O   . HIS B 1 183 ? 111.461 124.590 116.069 1.00 71.08  ? 183 HIS B O   1 
ATOM   4834 C  CB  . HIS B 1 183 ? 112.491 125.908 113.629 1.00 71.08  ? 183 HIS B CB  1 
ATOM   4835 C  CG  . HIS B 1 183 ? 112.722 125.981 112.157 1.00 71.08  ? 183 HIS B CG  1 
ATOM   4836 N  ND1 . HIS B 1 183 ? 113.185 127.115 111.533 1.00 71.08  ? 183 HIS B ND1 1 
ATOM   4837 C  CD2 . HIS B 1 183 ? 112.538 125.064 111.182 1.00 71.08  ? 183 HIS B CD2 1 
ATOM   4838 C  CE1 . HIS B 1 183 ? 113.281 126.893 110.237 1.00 71.08  ? 183 HIS B CE1 1 
ATOM   4839 N  NE2 . HIS B 1 183 ? 112.895 125.655 109.998 1.00 71.08  ? 183 HIS B NE2 1 
ATOM   4840 N  N   . VAL B 1 184 ? 110.214 126.448 116.177 1.00 71.52  ? 184 VAL B N   1 
ATOM   4841 C  CA  . VAL B 1 184 ? 109.922 126.325 117.600 1.00 71.52  ? 184 VAL B CA  1 
ATOM   4842 C  C   . VAL B 1 184 ? 108.541 125.701 117.728 1.00 71.52  ? 184 VAL B C   1 
ATOM   4843 O  O   . VAL B 1 184 ? 107.551 126.330 117.324 1.00 71.52  ? 184 VAL B O   1 
ATOM   4844 C  CB  . VAL B 1 184 ? 109.983 127.681 118.310 1.00 71.52  ? 184 VAL B CB  1 
ATOM   4845 C  CG1 . VAL B 1 184 ? 109.567 127.534 119.747 1.00 71.52  ? 184 VAL B CG1 1 
ATOM   4846 C  CG2 . VAL B 1 184 ? 111.367 128.243 118.224 1.00 71.52  ? 184 VAL B CG2 1 
ATOM   4847 N  N   . PRO B 1 185 ? 108.420 124.482 118.240 1.00 72.62  ? 185 PRO B N   1 
ATOM   4848 C  CA  . PRO B 1 185 ? 107.101 123.871 118.385 1.00 72.62  ? 185 PRO B CA  1 
ATOM   4849 C  C   . PRO B 1 185 ? 106.317 124.512 119.513 1.00 72.62  ? 185 PRO B C   1 
ATOM   4850 O  O   . PRO B 1 185 ? 106.887 124.943 120.516 1.00 72.62  ? 185 PRO B O   1 
ATOM   4851 C  CB  . PRO B 1 185 ? 107.422 122.408 118.691 1.00 72.62  ? 185 PRO B CB  1 
ATOM   4852 C  CG  . PRO B 1 185 ? 108.764 122.441 119.253 1.00 72.62  ? 185 PRO B CG  1 
ATOM   4853 C  CD  . PRO B 1 185 ? 109.491 123.536 118.565 1.00 72.62  ? 185 PRO B CD  1 
ATOM   4854 N  N   . ASN B 1 186 ? 104.994 124.549 119.325 1.00 74.12  ? 186 ASN B N   1 
ATOM   4855 C  CA  . ASN B 1 186 ? 104.052 125.268 120.184 1.00 74.12  ? 186 ASN B CA  1 
ATOM   4856 C  C   . ASN B 1 186 ? 104.448 126.733 120.320 1.00 74.12  ? 186 ASN B C   1 
ATOM   4857 O  O   . ASN B 1 186 ? 104.568 127.262 121.418 1.00 74.12  ? 186 ASN B O   1 
ATOM   4858 C  CB  . ASN B 1 186 ? 103.907 124.600 121.553 1.00 74.12  ? 186 ASN B CB  1 
ATOM   4859 C  CG  . ASN B 1 186 ? 102.648 125.007 122.265 1.00 74.12  ? 186 ASN B CG  1 
ATOM   4860 O  OD1 . ASN B 1 186 ? 101.547 124.796 121.768 1.00 74.12  ? 186 ASN B OD1 1 
ATOM   4861 N  ND2 . ASN B 1 186 ? 102.801 125.605 123.435 1.00 74.12  ? 186 ASN B ND2 1 
ATOM   4862 N  N   . TYR B 1 187 ? 104.677 127.372 119.185 1.00 74.55  ? 187 TYR B N   1 
ATOM   4863 C  CA  . TYR B 1 187 ? 105.005 128.787 119.156 1.00 74.55  ? 187 TYR B CA  1 
ATOM   4864 C  C   . TYR B 1 187 ? 103.827 129.600 119.689 1.00 74.55  ? 187 TYR B C   1 
ATOM   4865 O  O   . TYR B 1 187 ? 102.673 129.285 119.389 1.00 74.55  ? 187 TYR B O   1 
ATOM   4866 C  CB  . TYR B 1 187 ? 105.343 129.191 117.719 1.00 74.55  ? 187 TYR B CB  1 
ATOM   4867 C  CG  . TYR B 1 187 ? 105.693 130.636 117.506 1.00 74.55  ? 187 TYR B CG  1 
ATOM   4868 C  CD1 . TYR B 1 187 ? 106.987 131.078 117.679 1.00 74.55  ? 187 TYR B CD1 1 
ATOM   4869 C  CD2 . TYR B 1 187 ? 104.733 131.555 117.120 1.00 74.55  ? 187 TYR B CD2 1 
ATOM   4870 C  CE1 . TYR B 1 187 ? 107.314 132.387 117.485 1.00 74.55  ? 187 TYR B CE1 1 
ATOM   4871 C  CE2 . TYR B 1 187 ? 105.050 132.867 116.933 1.00 74.55  ? 187 TYR B CE2 1 
ATOM   4872 C  CZ  . TYR B 1 187 ? 106.342 133.276 117.114 1.00 74.55  ? 187 TYR B CZ  1 
ATOM   4873 O  OH  . TYR B 1 187 ? 106.672 134.588 116.919 1.00 74.55  ? 187 TYR B OH  1 
ATOM   4874 N  N   . PRO B 1 188 ? 104.072 130.643 120.492 1.00 75.22  ? 188 PRO B N   1 
ATOM   4875 C  CA  . PRO B 1 188 ? 105.353 131.164 120.956 1.00 75.22  ? 188 PRO B CA  1 
ATOM   4876 C  C   . PRO B 1 188 ? 105.747 130.715 122.350 1.00 75.22  ? 188 PRO B C   1 
ATOM   4877 O  O   . PRO B 1 188 ? 106.615 131.331 122.951 1.00 75.22  ? 188 PRO B O   1 
ATOM   4878 C  CB  . PRO B 1 188 ? 105.115 132.664 120.941 1.00 75.22  ? 188 PRO B CB  1 
ATOM   4879 C  CG  . PRO B 1 188 ? 103.702 132.784 121.342 1.00 75.22  ? 188 PRO B CG  1 
ATOM   4880 C  CD  . PRO B 1 188 ? 102.980 131.562 120.837 1.00 75.22  ? 188 PRO B CD  1 
ATOM   4881 N  N   . ASN B 1 189 ? 105.122 129.660 122.863 1.00 78.11  ? 189 ASN B N   1 
ATOM   4882 C  CA  . ASN B 1 189 ? 105.381 129.163 124.212 1.00 78.11  ? 189 ASN B CA  1 
ATOM   4883 C  C   . ASN B 1 189 ? 105.834 127.713 124.135 1.00 78.11  ? 189 ASN B C   1 
ATOM   4884 O  O   . ASN B 1 189 ? 105.018 126.797 124.304 1.00 78.11  ? 189 ASN B O   1 
ATOM   4885 C  CB  . ASN B 1 189 ? 104.140 129.281 125.088 1.00 78.11  ? 189 ASN B CB  1 
ATOM   4886 C  CG  . ASN B 1 189 ? 103.637 130.693 125.191 1.00 78.11  ? 189 ASN B CG  1 
ATOM   4887 O  OD1 . ASN B 1 189 ? 104.215 131.514 125.894 1.00 78.11  ? 189 ASN B OD1 1 
ATOM   4888 N  ND2 . ASN B 1 189 ? 102.549 130.985 124.496 1.00 78.11  ? 189 ASN B ND2 1 
ATOM   4889 N  N   . PRO B 1 190 ? 107.106 127.457 123.850 1.00 76.85  ? 190 PRO B N   1 
ATOM   4890 C  CA  . PRO B 1 190 ? 107.588 126.079 123.873 1.00 76.85  ? 190 PRO B CA  1 
ATOM   4891 C  C   . PRO B 1 190 ? 107.661 125.563 125.296 1.00 76.85  ? 190 PRO B C   1 
ATOM   4892 O  O   . PRO B 1 190 ? 107.791 126.327 126.254 1.00 76.85  ? 190 PRO B O   1 
ATOM   4893 C  CB  . PRO B 1 190 ? 108.976 126.179 123.241 1.00 76.85  ? 190 PRO B CB  1 
ATOM   4894 C  CG  . PRO B 1 190 ? 109.392 127.556 123.498 1.00 76.85  ? 190 PRO B CG  1 
ATOM   4895 C  CD  . PRO B 1 190 ? 108.166 128.390 123.439 1.00 76.85  ? 190 PRO B CD  1 
ATOM   4896 N  N   . SER B 1 191 ? 107.548 124.248 125.427 1.00 80.37  ? 191 SER B N   1 
ATOM   4897 C  CA  . SER B 1 191 ? 107.571 123.635 126.741 1.00 80.37  ? 191 SER B CA  1 
ATOM   4898 C  C   . SER B 1 191 ? 108.969 123.706 127.337 1.00 80.37  ? 191 SER B C   1 
ATOM   4899 O  O   . SER B 1 191 ? 109.961 123.896 126.636 1.00 80.37  ? 191 SER B O   1 
ATOM   4900 C  CB  . SER B 1 191 ? 107.109 122.185 126.665 1.00 80.37  ? 191 SER B CB  1 
ATOM   4901 O  OG  . SER B 1 191 ? 107.955 121.428 125.828 1.00 80.37  ? 191 SER B OG  1 
ATOM   4902 N  N   . ASP B 1 192 ? 109.035 123.556 128.660 1.00 83.95  ? 192 ASP B N   1 
ATOM   4903 C  CA  . ASP B 1 192 ? 110.323 123.566 129.343 1.00 83.95  ? 192 ASP B CA  1 
ATOM   4904 C  C   . ASP B 1 192 ? 111.131 122.323 129.010 1.00 83.95  ? 192 ASP B C   1 
ATOM   4905 O  O   . ASP B 1 192 ? 112.361 122.328 129.112 1.00 83.95  ? 192 ASP B O   1 
ATOM   4906 C  CB  . ASP B 1 192 ? 110.112 123.678 130.848 1.00 83.95  ? 192 ASP B CB  1 
ATOM   4907 C  CG  . ASP B 1 192 ? 109.587 125.027 131.256 1.00 83.95  ? 192 ASP B CG  1 
ATOM   4908 O  OD1 . ASP B 1 192 ? 109.884 126.011 130.554 1.00 83.95  ? 192 ASP B OD1 1 
ATOM   4909 O  OD2 . ASP B 1 192 ? 108.880 125.112 132.277 1.00 83.95  ? 192 ASP B OD2 1 
ATOM   4910 N  N   . GLU B 1 193 ? 110.450 121.246 128.625 1.00 83.81  ? 193 GLU B N   1 
ATOM   4911 C  CA  . GLU B 1 193 ? 111.134 120.057 128.139 1.00 83.81  ? 193 GLU B CA  1 
ATOM   4912 C  C   . GLU B 1 193 ? 111.855 120.331 126.829 1.00 83.81  ? 193 GLU B C   1 
ATOM   4913 O  O   . GLU B 1 193 ? 112.981 119.866 126.627 1.00 83.81  ? 193 GLU B O   1 
ATOM   4914 C  CB  . GLU B 1 193 ? 110.126 118.926 127.967 1.00 83.81  ? 193 GLU B CB  1 
ATOM   4915 C  CG  . GLU B 1 193 ? 110.714 117.632 127.466 1.00 83.81  ? 193 GLU B CG  1 
ATOM   4916 C  CD  . GLU B 1 193 ? 109.668 116.553 127.319 1.00 83.81  ? 193 GLU B CD  1 
ATOM   4917 O  OE1 . GLU B 1 193 ? 108.487 116.830 127.614 1.00 83.81  ? 193 GLU B OE1 1 
ATOM   4918 O  OE2 . GLU B 1 193 ? 110.022 115.432 126.903 1.00 83.81  ? 193 GLU B OE2 1 
ATOM   4919 N  N   . TRP B 1 194 ? 111.227 121.091 125.929 1.00 74.32  ? 194 TRP B N   1 
ATOM   4920 C  CA  . TRP B 1 194 ? 111.834 121.342 124.628 1.00 74.32  ? 194 TRP B CA  1 
ATOM   4921 C  C   . TRP B 1 194 ? 113.000 122.306 124.738 1.00 74.32  ? 194 TRP B C   1 
ATOM   4922 O  O   . TRP B 1 194 ? 114.001 122.148 124.037 1.00 74.32  ? 194 TRP B O   1 
ATOM   4923 C  CB  . TRP B 1 194 ? 110.804 121.888 123.643 1.00 74.32  ? 194 TRP B CB  1 
ATOM   4924 C  CG  . TRP B 1 194 ? 111.361 122.035 122.260 1.00 74.32  ? 194 TRP B CG  1 
ATOM   4925 C  CD1 . TRP B 1 194 ? 111.391 121.086 121.292 1.00 74.32  ? 194 TRP B CD1 1 
ATOM   4926 C  CD2 . TRP B 1 194 ? 111.987 123.195 121.702 1.00 74.32  ? 194 TRP B CD2 1 
ATOM   4927 N  NE1 . TRP B 1 194 ? 111.992 121.577 120.167 1.00 74.32  ? 194 TRP B NE1 1 
ATOM   4928 C  CE2 . TRP B 1 194 ? 112.372 122.870 120.396 1.00 74.32  ? 194 TRP B CE2 1 
ATOM   4929 C  CE3 . TRP B 1 194 ? 112.265 124.473 122.185 1.00 74.32  ? 194 TRP B CE3 1 
ATOM   4930 C  CZ2 . TRP B 1 194 ? 113.007 123.775 119.565 1.00 74.32  ? 194 TRP B CZ2 1 
ATOM   4931 C  CZ3 . TRP B 1 194 ? 112.898 125.363 121.363 1.00 74.32  ? 194 TRP B CZ3 1 
ATOM   4932 C  CH2 . TRP B 1 194 ? 113.260 125.015 120.067 1.00 74.32  ? 194 TRP B CH2 1 
ATOM   4933 N  N   . VAL B 1 195 ? 112.878 123.318 125.594 1.00 74.83  ? 195 VAL B N   1 
ATOM   4934 C  CA  . VAL B 1 195 ? 113.921 124.330 125.713 1.00 74.83  ? 195 VAL B CA  1 
ATOM   4935 C  C   . VAL B 1 195 ? 115.168 123.735 126.347 1.00 74.83  ? 195 VAL B C   1 
ATOM   4936 O  O   . VAL B 1 195 ? 116.294 124.034 125.938 1.00 74.83  ? 195 VAL B O   1 
ATOM   4937 C  CB  . VAL B 1 195 ? 113.386 125.538 126.501 1.00 74.83  ? 195 VAL B CB  1 
ATOM   4938 C  CG1 . VAL B 1 195 ? 114.452 126.586 126.690 1.00 74.83  ? 195 VAL B CG1 1 
ATOM   4939 C  CG2 . VAL B 1 195 ? 112.220 126.137 125.771 1.00 74.83  ? 195 VAL B CG2 1 
ATOM   4940 N  N   . GLU B 1 196 ? 114.987 122.841 127.315 1.00 79.89  ? 196 GLU B N   1 
ATOM   4941 C  CA  . GLU B 1 196 ? 116.128 122.160 127.908 1.00 79.89  ? 196 GLU B CA  1 
ATOM   4942 C  C   . GLU B 1 196 ? 116.737 121.159 126.935 1.00 79.89  ? 196 GLU B C   1 
ATOM   4943 O  O   . GLU B 1 196 ? 117.954 120.949 126.927 1.00 79.89  ? 196 GLU B O   1 
ATOM   4944 C  CB  . GLU B 1 196 ? 115.704 121.479 129.208 1.00 79.89  ? 196 GLU B CB  1 
ATOM   4945 C  CG  . GLU B 1 196 ? 116.839 120.812 129.952 1.00 79.89  ? 196 GLU B CG  1 
ATOM   4946 C  CD  . GLU B 1 196 ? 117.895 121.802 130.419 1.00 79.89  ? 196 GLU B CD  1 
ATOM   4947 O  OE1 . GLU B 1 196 ? 117.544 122.953 130.758 1.00 79.89  ? 196 GLU B OE1 1 
ATOM   4948 O  OE2 . GLU B 1 196 ? 119.089 121.439 130.414 1.00 79.89  ? 196 GLU B OE2 1 
ATOM   4949 N  N   . GLN B 1 197 ? 115.912 120.555 126.086 1.00 77.50  ? 197 GLN B N   1 
ATOM   4950 C  CA  . GLN B 1 197 ? 116.437 119.665 125.059 1.00 77.50  ? 197 GLN B CA  1 
ATOM   4951 C  C   . GLN B 1 197 ? 117.128 120.450 123.950 1.00 77.50  ? 197 GLN B C   1 
ATOM   4952 O  O   . GLN B 1 197 ? 118.105 119.977 123.362 1.00 77.50  ? 197 GLN B O   1 
ATOM   4953 C  CB  . GLN B 1 197 ? 115.307 118.800 124.510 1.00 77.50  ? 197 GLN B CB  1 
ATOM   4954 C  CG  . GLN B 1 197 ? 115.735 117.781 123.491 1.00 77.50  ? 197 GLN B CG  1 
ATOM   4955 C  CD  . GLN B 1 197 ? 116.723 116.790 124.057 1.00 77.50  ? 197 GLN B CD  1 
ATOM   4956 O  OE1 . GLN B 1 197 ? 116.580 116.333 125.190 1.00 77.50  ? 197 GLN B OE1 1 
ATOM   4957 N  NE2 . GLN B 1 197 ? 117.738 116.455 123.275 1.00 77.50  ? 197 GLN B NE2 1 
ATOM   4958 N  N   . TRP B 1 198 ? 116.642 121.659 123.664 1.00 70.82  ? 198 TRP B N   1 
ATOM   4959 C  CA  . TRP B 1 198 ? 117.274 122.511 122.663 1.00 70.82  ? 198 TRP B CA  1 
ATOM   4960 C  C   . TRP B 1 198 ? 118.655 122.960 123.112 1.00 70.82  ? 198 TRP B C   1 
ATOM   4961 O  O   . TRP B 1 198 ? 119.579 123.054 122.300 1.00 70.82  ? 198 TRP B O   1 
ATOM   4962 C  CB  . TRP B 1 198 ? 116.376 123.712 122.374 1.00 70.82  ? 198 TRP B CB  1 
ATOM   4963 C  CG  . TRP B 1 198 ? 117.058 124.943 121.878 1.00 70.82  ? 198 TRP B CG  1 
ATOM   4964 C  CD1 . TRP B 1 198 ? 117.440 126.014 122.616 1.00 70.82  ? 198 TRP B CD1 1 
ATOM   4965 C  CD2 . TRP B 1 198 ? 117.387 125.254 120.526 1.00 70.82  ? 198 TRP B CD2 1 
ATOM   4966 N  NE1 . TRP B 1 198 ? 118.012 126.961 121.818 1.00 70.82  ? 198 TRP B NE1 1 
ATOM   4967 C  CE2 . TRP B 1 198 ? 117.989 126.518 120.526 1.00 70.82  ? 198 TRP B CE2 1 
ATOM   4968 C  CE3 . TRP B 1 198 ? 117.243 124.578 119.317 1.00 70.82  ? 198 TRP B CE3 1 
ATOM   4969 C  CZ2 . TRP B 1 198 ? 118.445 127.122 119.368 1.00 70.82  ? 198 TRP B CZ2 1 
ATOM   4970 C  CZ3 . TRP B 1 198 ? 117.693 125.178 118.172 1.00 70.82  ? 198 TRP B CZ3 1 
ATOM   4971 C  CH2 . TRP B 1 198 ? 118.288 126.437 118.202 1.00 70.82  ? 198 TRP B CH2 1 
ATOM   4972 N  N   . PHE B 1 199 ? 118.819 123.237 124.402 1.00 71.30  ? 199 PHE B N   1 
ATOM   4973 C  CA  . PHE B 1 199 ? 120.122 123.661 124.888 1.00 71.30  ? 199 PHE B CA  1 
ATOM   4974 C  C   . PHE B 1 199 ? 121.072 122.486 125.028 1.00 71.30  ? 199 PHE B C   1 
ATOM   4975 O  O   . PHE B 1 199 ? 122.292 122.668 125.012 1.00 71.30  ? 199 PHE B O   1 
ATOM   4976 C  CB  . PHE B 1 199 ? 119.971 124.388 126.214 1.00 71.30  ? 199 PHE B CB  1 
ATOM   4977 C  CG  . PHE B 1 199 ? 119.619 125.822 126.063 1.00 71.30  ? 199 PHE B CG  1 
ATOM   4978 C  CD1 . PHE B 1 199 ? 120.455 126.678 125.374 1.00 71.30  ? 199 PHE B CD1 1 
ATOM   4979 C  CD2 . PHE B 1 199 ? 118.449 126.318 126.589 1.00 71.30  ? 199 PHE B CD2 1 
ATOM   4980 C  CE1 . PHE B 1 199 ? 120.134 128.001 125.223 1.00 71.30  ? 199 PHE B CE1 1 
ATOM   4981 C  CE2 . PHE B 1 199 ? 118.123 127.640 126.438 1.00 71.30  ? 199 PHE B CE2 1 
ATOM   4982 C  CZ  . PHE B 1 199 ? 118.967 128.482 125.757 1.00 71.30  ? 199 PHE B CZ  1 
ATOM   4983 N  N   . ALA B 1 200 ? 120.536 121.276 125.165 1.00 72.67  ? 200 ALA B N   1 
ATOM   4984 C  CA  . ALA B 1 200 ? 121.388 120.099 125.227 1.00 72.67  ? 200 ALA B CA  1 
ATOM   4985 C  C   . ALA B 1 200 ? 121.974 119.778 123.864 1.00 72.67  ? 200 ALA B C   1 
ATOM   4986 O  O   . ALA B 1 200 ? 123.126 119.346 123.763 1.00 72.67  ? 200 ALA B O   1 
ATOM   4987 C  CB  . ALA B 1 200 ? 120.599 118.910 125.762 1.00 72.67  ? 200 ALA B CB  1 
ATOM   4988 N  N   . LEU B 1 201 ? 121.198 119.994 122.805 1.00 73.19  ? 201 LEU B N   1 
ATOM   4989 C  CA  . LEU B 1 201 ? 121.664 119.678 121.462 1.00 73.19  ? 201 LEU B CA  1 
ATOM   4990 C  C   . LEU B 1 201 ? 122.689 120.688 120.973 1.00 73.19  ? 201 LEU B C   1 
ATOM   4991 O  O   . LEU B 1 201 ? 123.535 120.363 120.137 1.00 73.19  ? 201 LEU B O   1 
ATOM   4992 C  CB  . LEU B 1 201 ? 120.483 119.627 120.506 1.00 73.19  ? 201 LEU B CB  1 
ATOM   4993 C  CG  . LEU B 1 201 ? 119.529 118.450 120.612 1.00 73.19  ? 201 LEU B CG  1 
ATOM   4994 C  CD1 . LEU B 1 201 ? 118.344 118.680 119.712 1.00 73.19  ? 201 LEU B CD1 1 
ATOM   4995 C  CD2 . LEU B 1 201 ? 120.240 117.187 120.235 1.00 73.19  ? 201 LEU B CD2 1 
ATOM   4996 N  N   . LEU B 1 202 ? 122.623 121.921 121.470 1.00 71.93  ? 202 LEU B N   1 
ATOM   4997 C  CA  . LEU B 1 202 ? 123.593 122.929 121.064 1.00 71.93  ? 202 LEU B CA  1 
ATOM   4998 C  C   . LEU B 1 202 ? 124.966 122.633 121.644 1.00 71.93  ? 202 LEU B C   1 
ATOM   4999 O  O   . LEU B 1 202 ? 125.988 122.906 121.009 1.00 71.93  ? 202 LEU B O   1 
ATOM   5000 C  CB  . LEU B 1 202 ? 123.130 124.315 121.497 1.00 71.93  ? 202 LEU B CB  1 
ATOM   5001 C  CG  . LEU B 1 202 ? 121.956 124.960 120.776 1.00 71.93  ? 202 LEU B CG  1 
ATOM   5002 C  CD1 . LEU B 1 202 ? 121.413 126.061 121.637 1.00 71.93  ? 202 LEU B CD1 1 
ATOM   5003 C  CD2 . LEU B 1 202 ? 122.398 125.513 119.459 1.00 71.93  ? 202 LEU B CD2 1 
ATOM   5004 N  N   . SER B 1 203 ? 125.011 122.076 122.850 1.00 75.05  ? 203 SER B N   1 
ATOM   5005 C  CA  . SER B 1 203 ? 126.295 121.751 123.454 1.00 75.05  ? 203 SER B CA  1 
ATOM   5006 C  C   . SER B 1 203 ? 126.830 120.429 122.930 1.00 75.05  ? 203 SER B C   1 
ATOM   5007 O  O   . SER B 1 203 ? 128.043 120.196 122.944 1.00 75.05  ? 203 SER B O   1 
ATOM   5008 C  CB  . SER B 1 203 ? 126.163 121.709 124.970 1.00 75.05  ? 203 SER B CB  1 
ATOM   5009 O  OG  . SER B 1 203 ? 125.701 120.439 125.382 1.00 75.05  ? 203 SER B OG  1 
ATOM   5010 N  N   . THR B 1 204 ? 125.940 119.546 122.476 1.00 73.81  ? 204 THR B N   1 
ATOM   5011 C  CA  . THR B 1 204 ? 126.369 118.279 121.897 1.00 73.81  ? 204 THR B CA  1 
ATOM   5012 C  C   . THR B 1 204 ? 127.081 118.495 120.572 1.00 73.81  ? 204 THR B C   1 
ATOM   5013 O  O   . THR B 1 204 ? 128.180 117.976 120.354 1.00 73.81  ? 204 THR B O   1 
ATOM   5014 C  CB  . THR B 1 204 ? 125.165 117.361 121.709 1.00 73.81  ? 204 THR B CB  1 
ATOM   5015 O  OG1 . THR B 1 204 ? 124.646 116.990 122.988 1.00 73.81  ? 204 THR B OG1 1 
ATOM   5016 C  CG2 . THR B 1 204 ? 125.542 116.114 120.948 1.00 73.81  ? 204 THR B CG2 1 
ATOM   5017 N  N   . TYR B 1 205 ? 126.485 119.279 119.685 1.00 73.53  ? 205 TYR B N   1 
ATOM   5018 C  CA  . TYR B 1 205 ? 127.027 119.493 118.358 1.00 73.53  ? 205 TYR B CA  1 
ATOM   5019 C  C   . TYR B 1 205 ? 127.877 120.746 118.256 1.00 73.53  ? 205 TYR B C   1 
ATOM   5020 O  O   . TYR B 1 205 ? 128.403 121.028 117.181 1.00 73.53  ? 205 TYR B O   1 
ATOM   5021 C  CB  . TYR B 1 205 ? 125.891 119.540 117.342 1.00 73.53  ? 205 TYR B CB  1 
ATOM   5022 C  CG  . TYR B 1 205 ? 125.160 118.232 117.252 1.00 73.53  ? 205 TYR B CG  1 
ATOM   5023 C  CD1 . TYR B 1 205 ? 125.716 117.158 116.584 1.00 73.53  ? 205 TYR B CD1 1 
ATOM   5024 C  CD2 . TYR B 1 205 ? 123.930 118.061 117.857 1.00 73.53  ? 205 TYR B CD2 1 
ATOM   5025 C  CE1 . TYR B 1 205 ? 125.063 115.959 116.509 1.00 73.53  ? 205 TYR B CE1 1 
ATOM   5026 C  CE2 . TYR B 1 205 ? 123.269 116.864 117.787 1.00 73.53  ? 205 TYR B CE2 1 
ATOM   5027 C  CZ  . TYR B 1 205 ? 123.841 115.818 117.111 1.00 73.53  ? 205 TYR B CZ  1 
ATOM   5028 O  OH  . TYR B 1 205 ? 123.187 114.617 117.037 1.00 73.53  ? 205 TYR B OH  1 
ATOM   5029 N  N   . GLY B 1 206 ? 128.033 121.492 119.341 1.00 73.01  ? 206 GLY B N   1 
ATOM   5030 C  CA  . GLY B 1 206 ? 128.934 122.627 119.347 1.00 73.01  ? 206 GLY B CA  1 
ATOM   5031 C  C   . GLY B 1 206 ? 128.453 123.807 118.536 1.00 73.01  ? 206 GLY B C   1 
ATOM   5032 O  O   . GLY B 1 206 ? 129.262 124.517 117.933 1.00 73.01  ? 206 GLY B O   1 
ATOM   5033 N  N   . LEU B 1 207 ? 127.150 124.034 118.512 1.00 71.35  ? 207 LEU B N   1 
ATOM   5034 C  CA  . LEU B 1 207 ? 126.558 125.117 117.750 1.00 71.35  ? 207 LEU B CA  1 
ATOM   5035 C  C   . LEU B 1 207 ? 126.125 126.233 118.683 1.00 71.35  ? 207 LEU B C   1 
ATOM   5036 O  O   . LEU B 1 207 ? 125.735 125.991 119.825 1.00 71.35  ? 207 LEU B O   1 
ATOM   5037 C  CB  . LEU B 1 207 ? 125.358 124.623 116.949 1.00 71.35  ? 207 LEU B CB  1 
ATOM   5038 C  CG  . LEU B 1 207 ? 125.655 123.455 116.022 1.00 71.35  ? 207 LEU B CG  1 
ATOM   5039 C  CD1 . LEU B 1 207 ? 124.380 122.882 115.477 1.00 71.35  ? 207 LEU B CD1 1 
ATOM   5040 C  CD2 . LEU B 1 207 ? 126.547 123.915 114.905 1.00 71.35  ? 207 LEU B CD2 1 
ATOM   5041 N  N   . GLU B 1 208 ? 126.213 127.463 118.196 1.00 75.53  ? 208 GLU B N   1 
ATOM   5042 C  CA  . GLU B 1 208 ? 125.651 128.584 118.908 1.00 75.53  ? 208 GLU B CA  1 
ATOM   5043 C  C   . GLU B 1 208 ? 124.520 129.177 118.083 1.00 75.53  ? 208 GLU B C   1 
ATOM   5044 O  O   . GLU B 1 208 ? 124.623 129.238 116.852 1.00 75.53  ? 208 GLU B O   1 
ATOM   5045 C  CB  . GLU B 1 208 ? 126.706 129.658 119.218 1.00 75.53  ? 208 GLU B CB  1 
ATOM   5046 C  CG  . GLU B 1 208 ? 127.472 130.179 118.030 1.00 75.53  ? 208 GLU B CG  1 
ATOM   5047 C  CD  . GLU B 1 208 ? 128.035 131.565 118.258 1.00 75.53  ? 208 GLU B CD  1 
ATOM   5048 O  OE1 . GLU B 1 208 ? 129.140 131.846 117.754 1.00 75.53  ? 208 GLU B OE1 1 
ATOM   5049 O  OE2 . GLU B 1 208 ? 127.372 132.379 118.932 1.00 75.53  ? 208 GLU B OE2 1 
ATOM   5050 N  N   . PRO B 1 209 ? 123.418 129.572 118.702 1.00 72.76  ? 209 PRO B N   1 
ATOM   5051 C  CA  . PRO B 1 209 ? 122.334 130.181 117.935 1.00 72.76  ? 209 PRO B CA  1 
ATOM   5052 C  C   . PRO B 1 209 ? 122.678 131.608 117.558 1.00 72.76  ? 209 PRO B C   1 
ATOM   5053 O  O   . PRO B 1 209 ? 123.239 132.359 118.357 1.00 72.76  ? 209 PRO B O   1 
ATOM   5054 C  CB  . PRO B 1 209 ? 121.149 130.117 118.898 1.00 72.76  ? 209 PRO B CB  1 
ATOM   5055 C  CG  . PRO B 1 209 ? 121.741 130.027 120.222 1.00 72.76  ? 209 PRO B CG  1 
ATOM   5056 C  CD  . PRO B 1 209 ? 123.050 129.349 120.105 1.00 72.76  ? 209 PRO B CD  1 
ATOM   5057 N  N   . THR B 1 210 ? 122.363 131.978 116.319 1.00 72.68  ? 210 THR B N   1 
ATOM   5058 C  CA  . THR B 1 210 ? 122.705 133.305 115.822 1.00 72.68  ? 210 THR B CA  1 
ATOM   5059 C  C   . THR B 1 210 ? 121.481 134.163 115.537 1.00 72.68  ? 210 THR B C   1 
ATOM   5060 O  O   . THR B 1 210 ? 121.321 135.210 116.163 1.00 72.68  ? 210 THR B O   1 
ATOM   5061 C  CB  . THR B 1 210 ? 123.570 133.191 114.563 1.00 72.68  ? 210 THR B CB  1 
ATOM   5062 O  OG1 . THR B 1 210 ? 122.852 132.479 113.557 1.00 72.68  ? 210 THR B OG1 1 
ATOM   5063 C  CG2 . THR B 1 210 ? 124.842 132.456 114.862 1.00 72.68  ? 210 THR B CG2 1 
ATOM   5064 N  N   . ASN B 1 211 ? 120.590 133.745 114.650 1.00 72.24  ? 211 ASN B N   1 
ATOM   5065 C  CA  . ASN B 1 211 ? 119.533 134.615 114.160 1.00 72.24  ? 211 ASN B CA  1 
ATOM   5066 C  C   . ASN B 1 211 ? 118.192 133.903 114.206 1.00 72.24  ? 211 ASN B C   1 
ATOM   5067 O  O   . ASN B 1 211 ? 118.082 132.746 113.800 1.00 72.24  ? 211 ASN B O   1 
ATOM   5068 C  CB  . ASN B 1 211 ? 119.834 135.071 112.735 1.00 72.24  ? 211 ASN B CB  1 
ATOM   5069 C  CG  . ASN B 1 211 ? 118.768 135.974 112.172 1.00 72.24  ? 211 ASN B CG  1 
ATOM   5070 O  OD1 . ASN B 1 211 ? 118.623 137.109 112.595 1.00 72.24  ? 211 ASN B OD1 1 
ATOM   5071 N  ND2 . ASN B 1 211 ? 118.021 135.477 111.205 1.00 72.24  ? 211 ASN B ND2 1 
ATOM   5072 N  N   . MET B 1 212 ? 117.175 134.601 114.700 1.00 74.11  ? 212 MET B N   1 
ATOM   5073 C  CA  . MET B 1 212 ? 115.808 134.101 114.719 1.00 74.11  ? 212 MET B CA  1 
ATOM   5074 C  C   . MET B 1 212 ? 114.952 134.988 113.832 1.00 74.11  ? 212 MET B C   1 
ATOM   5075 O  O   . MET B 1 212 ? 114.874 136.198 114.052 1.00 74.11  ? 212 MET B O   1 
ATOM   5076 C  CB  . MET B 1 212 ? 115.246 134.067 116.136 1.00 74.11  ? 212 MET B CB  1 
ATOM   5077 C  CG  . MET B 1 212 ? 114.222 132.973 116.347 1.00 74.11  ? 212 MET B CG  1 
ATOM   5078 S  SD  . MET B 1 212 ? 113.229 133.193 117.824 1.00 74.11  ? 212 MET B SD  1 
ATOM   5079 C  CE  . MET B 1 212 ? 112.135 134.496 117.292 1.00 74.11  ? 212 MET B CE  1 
ATOM   5080 N  N   . GLY B 1 213 ? 114.307 134.387 112.839 1.00 73.97  ? 213 GLY B N   1 
ATOM   5081 C  CA  . GLY B 1 213 ? 113.486 135.156 111.926 1.00 73.97  ? 213 GLY B CA  1 
ATOM   5082 C  C   . GLY B 1 213 ? 112.095 135.386 112.484 1.00 73.97  ? 213 GLY B C   1 
ATOM   5083 O  O   . GLY B 1 213 ? 111.492 134.506 113.094 1.00 73.97  ? 213 GLY B O   1 
ATOM   5084 N  N   . SER B 1 214 ? 111.579 136.586 112.255 1.00 74.88  ? 214 SER B N   1 
ATOM   5085 C  CA  . SER B 1 214 ? 110.301 137.004 112.801 1.00 74.88  ? 214 SER B CA  1 
ATOM   5086 C  C   . SER B 1 214 ? 109.487 137.689 111.718 1.00 74.88  ? 214 SER B C   1 
ATOM   5087 O  O   . SER B 1 214 ? 110.024 138.176 110.724 1.00 74.88  ? 214 SER B O   1 
ATOM   5088 C  CB  . SER B 1 214 ? 110.493 137.947 113.986 1.00 74.88  ? 214 SER B CB  1 
ATOM   5089 O  OG  . SER B 1 214 ? 109.257 138.459 114.429 1.00 74.88  ? 214 SER B OG  1 
ATOM   5090 N  N   . TRP B 1 215 ? 108.175 137.718 111.921 1.00 75.28  ? 215 TRP B N   1 
ATOM   5091 C  CA  . TRP B 1 215 ? 107.259 138.392 111.016 1.00 75.28  ? 215 TRP B CA  1 
ATOM   5092 C  C   . TRP B 1 215 ? 106.372 139.332 111.804 1.00 75.28  ? 215 TRP B C   1 
ATOM   5093 O  O   . TRP B 1 215 ? 106.048 139.070 112.962 1.00 75.28  ? 215 TRP B O   1 
ATOM   5094 C  CB  . TRP B 1 215 ? 106.390 137.404 110.248 1.00 75.28  ? 215 TRP B CB  1 
ATOM   5095 C  CG  . TRP B 1 215 ? 107.134 136.677 109.215 1.00 75.28  ? 215 TRP B CG  1 
ATOM   5096 C  CD1 . TRP B 1 215 ? 107.254 137.012 107.908 1.00 75.28  ? 215 TRP B CD1 1 
ATOM   5097 C  CD2 . TRP B 1 215 ? 107.889 135.485 109.398 1.00 75.28  ? 215 TRP B CD2 1 
ATOM   5098 N  NE1 . TRP B 1 215 ? 108.036 136.099 107.258 1.00 75.28  ? 215 TRP B NE1 1 
ATOM   5099 C  CE2 . TRP B 1 215 ? 108.440 135.149 108.155 1.00 75.28  ? 215 TRP B CE2 1 
ATOM   5100 C  CE3 . TRP B 1 215 ? 108.152 134.667 110.497 1.00 75.28  ? 215 TRP B CE3 1 
ATOM   5101 C  CZ2 . TRP B 1 215 ? 109.237 134.032 107.978 1.00 75.28  ? 215 TRP B CZ2 1 
ATOM   5102 C  CZ3 . TRP B 1 215 ? 108.938 133.563 110.319 1.00 75.28  ? 215 TRP B CZ3 1 
ATOM   5103 C  CH2 . TRP B 1 215 ? 109.473 133.252 109.071 1.00 75.28  ? 215 TRP B CH2 1 
ATOM   5104 N  N   . ILE B 1 216 ? 105.999 140.434 111.177 1.00 78.41  ? 216 ILE B N   1 
ATOM   5105 C  CA  . ILE B 1 216 ? 104.973 141.329 111.685 1.00 78.41  ? 216 ILE B CA  1 
ATOM   5106 C  C   . ILE B 1 216 ? 103.903 141.382 110.605 1.00 78.41  ? 216 ILE B C   1 
ATOM   5107 O  O   . ILE B 1 216 ? 104.005 142.162 109.654 1.00 78.41  ? 216 ILE B O   1 
ATOM   5108 C  CB  . ILE B 1 216 ? 105.522 142.720 112.007 1.00 78.41  ? 216 ILE B CB  1 
ATOM   5109 C  CG1 . ILE B 1 216 ? 106.677 142.619 112.992 1.00 78.41  ? 216 ILE B CG1 1 
ATOM   5110 C  CG2 . ILE B 1 216 ? 104.446 143.591 112.601 1.00 78.41  ? 216 ILE B CG2 1 
ATOM   5111 C  CD1 . ILE B 1 216 ? 107.708 143.671 112.798 1.00 78.41  ? 216 ILE B CD1 1 
ATOM   5112 N  N   . ASP B 1 217 ? 102.885 140.541 110.733 1.00 81.83  ? 217 ASP B N   1 
ATOM   5113 C  CA  . ASP B 1 217 ? 101.875 140.383 109.692 1.00 81.83  ? 217 ASP B CA  1 
ATOM   5114 C  C   . ASP B 1 217 ? 100.892 141.538 109.754 1.00 81.83  ? 217 ASP B C   1 
ATOM   5115 O  O   . ASP B 1 217 ? 99.966  141.526 110.563 1.00 81.83  ? 217 ASP B O   1 
ATOM   5116 C  CB  . ASP B 1 217 ? 101.146 139.058 109.859 1.00 81.83  ? 217 ASP B CB  1 
ATOM   5117 C  CG  . ASP B 1 217 ? 102.063 137.876 109.741 1.00 81.83  ? 217 ASP B CG  1 
ATOM   5118 O  OD1 . ASP B 1 217 ? 102.701 137.723 108.684 1.00 81.83  ? 217 ASP B OD1 1 
ATOM   5119 O  OD2 . ASP B 1 217 ? 102.146 137.094 110.705 1.00 81.83  ? 217 ASP B OD2 1 
ATOM   5120 N  N   . THR B 1 218 ? 101.072 142.527 108.885 1.00 82.67  ? 218 THR B N   1 
ATOM   5121 C  CA  . THR B 1 218 ? 100.208 143.695 108.913 1.00 82.67  ? 218 THR B CA  1 
ATOM   5122 C  C   . THR B 1 218 ? 98.828  143.419 108.346 1.00 82.67  ? 218 THR B C   1 
ATOM   5123 O  O   . THR B 1 218 ? 97.894  144.168 108.639 1.00 82.67  ? 218 THR B O   1 
ATOM   5124 C  CB  . THR B 1 218 ? 100.854 144.848 108.155 1.00 82.67  ? 218 THR B CB  1 
ATOM   5125 O  OG1 . THR B 1 218 ? 101.010 144.489 106.781 1.00 82.67  ? 218 THR B OG1 1 
ATOM   5126 C  CG2 . THR B 1 218 ? 102.203 145.155 108.742 1.00 82.67  ? 218 THR B CG2 1 
ATOM   5127 N  N   . ARG B 1 219 ? 98.670  142.363 107.556 1.00 81.91  ? 219 ARG B N   1 
ATOM   5128 C  CA  . ARG B 1 219 ? 97.372  141.957 107.043 1.00 81.91  ? 219 ARG B CA  1 
ATOM   5129 C  C   . ARG B 1 219 ? 96.780  140.827 107.865 1.00 81.91  ? 219 ARG B C   1 
ATOM   5130 O  O   . ARG B 1 219 ? 96.166  139.912 107.316 1.00 81.91  ? 219 ARG B O   1 
ATOM   5131 C  CB  . ARG B 1 219 ? 97.474  141.555 105.577 1.00 81.91  ? 219 ARG B CB  1 
ATOM   5132 C  CG  . ARG B 1 219 ? 97.861  142.689 104.669 1.00 81.91  ? 219 ARG B CG  1 
ATOM   5133 C  CD  . ARG B 1 219 ? 98.068  142.208 103.264 1.00 81.91  ? 219 ARG B CD  1 
ATOM   5134 N  NE  . ARG B 1 219 ? 99.044  143.026 102.564 1.00 81.91  ? 219 ARG B NE  1 
ATOM   5135 C  CZ  . ARG B 1 219 ? 99.793  142.588 101.564 1.00 81.91  ? 219 ARG B CZ  1 
ATOM   5136 N  NH1 . ARG B 1 219 ? 99.674  141.340 101.148 1.00 81.91  ? 219 ARG B NH1 1 
ATOM   5137 N  NH2 . ARG B 1 219 ? 100.660 143.396 100.982 1.00 81.91  ? 219 ARG B NH2 1 
ATOM   5138 N  N   . LEU B 1 220 ? 96.989  140.874 109.180 1.00 79.69  ? 220 LEU B N   1 
ATOM   5139 C  CA  . LEU B 1 220 ? 96.531  139.811 110.064 1.00 79.69  ? 220 LEU B CA  1 
ATOM   5140 C  C   . LEU B 1 220 ? 95.015  139.762 110.135 1.00 79.69  ? 220 LEU B C   1 
ATOM   5141 O  O   . LEU B 1 220 ? 94.424  138.680 110.154 1.00 79.69  ? 220 LEU B O   1 
ATOM   5142 C  CB  . LEU B 1 220 ? 97.124  140.017 111.453 1.00 79.69  ? 220 LEU B CB  1 
ATOM   5143 C  CG  . LEU B 1 220 ? 96.877  138.939 112.498 1.00 79.69  ? 220 LEU B CG  1 
ATOM   5144 C  CD1 . LEU B 1 220 ? 97.758  137.758 112.231 1.00 79.69  ? 220 LEU B CD1 1 
ATOM   5145 C  CD2 . LEU B 1 220 ? 97.139  139.494 113.875 1.00 79.69  ? 220 LEU B CD2 1 
ATOM   5146 N  N   . HIS B 1 221 ? 94.365  140.922 110.161 1.00 82.26  ? 221 HIS B N   1 
ATOM   5147 C  CA  . HIS B 1 221 ? 92.912  141.001 110.209 1.00 82.26  ? 221 HIS B CA  1 
ATOM   5148 C  C   . HIS B 1 221 ? 92.359  141.818 109.053 1.00 82.26  ? 221 HIS B C   1 
ATOM   5149 O  O   . HIS B 1 221 ? 91.476  142.651 109.245 1.00 82.26  ? 221 HIS B O   1 
ATOM   5150 C  CB  . HIS B 1 221 ? 92.457  141.578 111.542 1.00 82.26  ? 221 HIS B CB  1 
ATOM   5151 C  CG  . HIS B 1 221 ? 92.784  140.703 112.706 1.00 82.26  ? 221 HIS B CG  1 
ATOM   5152 N  ND1 . HIS B 1 221 ? 92.096  139.542 112.976 1.00 82.26  ? 221 HIS B ND1 1 
ATOM   5153 C  CD2 . HIS B 1 221 ? 93.738  140.806 113.658 1.00 82.26  ? 221 HIS B CD2 1 
ATOM   5154 C  CE1 . HIS B 1 221 ? 92.605  138.972 114.051 1.00 82.26  ? 221 HIS B CE1 1 
ATOM   5155 N  NE2 . HIS B 1 221 ? 93.602  139.719 114.485 1.00 82.26  ? 221 HIS B NE2 1 
ATOM   5156 N  N   . SER B 1 222 ? 92.867  141.583 107.851 1.00 83.25  ? 222 SER B N   1 
ATOM   5157 C  CA  . SER B 1 222 ? 92.466  142.370 106.700 1.00 83.25  ? 222 SER B CA  1 
ATOM   5158 C  C   . SER B 1 222 ? 91.198  141.843 106.051 1.00 83.25  ? 222 SER B C   1 
ATOM   5159 O  O   . SER B 1 222 ? 90.485  142.605 105.392 1.00 83.25  ? 222 SER B O   1 
ATOM   5160 C  CB  . SER B 1 222 ? 93.598  142.396 105.681 1.00 83.25  ? 222 SER B CB  1 
ATOM   5161 O  OG  . SER B 1 222 ? 93.214  143.110 104.526 1.00 83.25  ? 222 SER B OG  1 
ATOM   5162 N  N   . SER B 1 223 ? 90.898  140.560 106.215 1.00 82.69  ? 223 SER B N   1 
ATOM   5163 C  CA  . SER B 1 223 ? 89.774  139.953 105.525 1.00 82.69  ? 223 SER B CA  1 
ATOM   5164 C  C   . SER B 1 223 ? 88.527  139.956 106.395 1.00 82.69  ? 223 SER B C   1 
ATOM   5165 O  O   . SER B 1 223 ? 88.596  139.949 107.625 1.00 82.69  ? 223 SER B O   1 
ATOM   5166 C  CB  . SER B 1 223 ? 90.103  138.521 105.114 1.00 82.69  ? 223 SER B CB  1 
ATOM   5167 O  OG  . SER B 1 223 ? 91.147  138.492 104.163 1.00 82.69  ? 223 SER B OG  1 
ATOM   5168 N  N   . GLY B 1 224 ? 87.377  139.968 105.735 1.00 89.37  ? 224 GLY B N   1 
ATOM   5169 C  CA  . GLY B 1 224 ? 86.114  139.829 106.413 1.00 89.37  ? 224 GLY B CA  1 
ATOM   5170 C  C   . GLY B 1 224 ? 85.314  141.108 106.472 1.00 89.37  ? 224 GLY B C   1 
ATOM   5171 O  O   . GLY B 1 224 ? 85.709  142.144 105.931 1.00 89.37  ? 224 GLY B O   1 
ATOM   5172 N  N   . PRO B 1 225 ? 84.154  141.052 107.127 1.00 95.47  ? 225 PRO B N   1 
ATOM   5173 C  CA  . PRO B 1 225 ? 83.359  142.276 107.295 1.00 95.47  ? 225 PRO B CA  1 
ATOM   5174 C  C   . PRO B 1 225 ? 83.966  143.229 108.300 1.00 95.47  ? 225 PRO B C   1 
ATOM   5175 O  O   . PRO B 1 225 ? 83.830  144.449 108.162 1.00 95.47  ? 225 PRO B O   1 
ATOM   5176 C  CB  . PRO B 1 225 ? 81.997  141.746 107.767 1.00 95.47  ? 225 PRO B CB  1 
ATOM   5177 C  CG  . PRO B 1 225 ? 82.040  140.267 107.545 1.00 95.47  ? 225 PRO B CG  1 
ATOM   5178 C  CD  . PRO B 1 225 ? 83.463  139.875 107.663 1.00 95.47  ? 225 PRO B CD  1 
ATOM   5179 N  N   . ASN B 1 226 ? 84.636  142.697 109.317 1.00 95.18  ? 226 ASN B N   1 
ATOM   5180 C  CA  . ASN B 1 226 ? 85.306  143.500 110.324 1.00 95.18  ? 226 ASN B CA  1 
ATOM   5181 C  C   . ASN B 1 226 ? 86.784  143.676 110.025 1.00 95.18  ? 226 ASN B C   1 
ATOM   5182 O  O   . ASN B 1 226 ? 87.587  143.781 110.956 1.00 95.18  ? 226 ASN B O   1 
ATOM   5183 C  CB  . ASN B 1 226 ? 85.117  142.872 111.701 1.00 95.18  ? 226 ASN B CB  1 
ATOM   5184 C  CG  . ASN B 1 226 ? 83.705  142.395 111.926 1.00 95.18  ? 226 ASN B CG  1 
ATOM   5185 O  OD1 . ASN B 1 226 ? 82.826  143.177 112.284 1.00 95.18  ? 226 ASN B OD1 1 
ATOM   5186 N  ND2 . ASN B 1 226 ? 83.474  141.107 111.714 1.00 95.18  ? 226 ASN B ND2 1 
ATOM   5187 N  N   . GLY B 1 227 ? 87.156  143.690 108.749 1.00 91.79  ? 227 GLY B N   1 
ATOM   5188 C  CA  . GLY B 1 227 ? 88.539  143.815 108.344 1.00 91.79  ? 227 GLY B CA  1 
ATOM   5189 C  C   . GLY B 1 227 ? 89.146  145.149 108.708 1.00 91.79  ? 227 GLY B C   1 
ATOM   5190 O  O   . GLY B 1 227 ? 88.568  146.201 108.425 1.00 91.79  ? 227 GLY B O   1 
ATOM   5191 N  N   . ARG B 1 228 ? 90.311  145.116 109.342 1.00 92.13  ? 228 ARG B N   1 
ATOM   5192 C  CA  . ARG B 1 228 ? 90.952  146.319 109.842 1.00 92.13  ? 228 ARG B CA  1 
ATOM   5193 C  C   . ARG B 1 228 ? 92.447  146.225 109.605 1.00 92.13  ? 228 ARG B C   1 
ATOM   5194 O  O   . ARG B 1 228 ? 92.963  145.208 109.139 1.00 92.13  ? 228 ARG B O   1 
ATOM   5195 C  CB  . ARG B 1 228 ? 90.671  146.520 111.328 1.00 92.13  ? 228 ARG B CB  1 
ATOM   5196 C  CG  . ARG B 1 228 ? 90.869  145.264 112.133 1.00 92.13  ? 228 ARG B CG  1 
ATOM   5197 C  CD  . ARG B 1 228 ? 90.507  145.475 113.576 1.00 92.13  ? 228 ARG B CD  1 
ATOM   5198 N  NE  . ARG B 1 228 ? 90.737  144.271 114.361 1.00 92.13  ? 228 ARG B NE  1 
ATOM   5199 C  CZ  . ARG B 1 228 ? 91.894  143.970 114.937 1.00 92.13  ? 228 ARG B CZ  1 
ATOM   5200 N  NH1 . ARG B 1 228 ? 92.930  144.789 114.817 1.00 92.13  ? 228 ARG B NH1 1 
ATOM   5201 N  NH2 . ARG B 1 228 ? 92.015  142.851 115.634 1.00 92.13  ? 228 ARG B NH2 1 
ATOM   5202 N  N   . ASP B 1 229 ? 93.141  147.302 109.934 1.00 92.78  ? 229 ASP B N   1 
ATOM   5203 C  CA  . ASP B 1 229 ? 94.584  147.322 109.798 1.00 92.78  ? 229 ASP B CA  1 
ATOM   5204 C  C   . ASP B 1 229 ? 95.249  147.149 111.155 1.00 92.78  ? 229 ASP B C   1 
ATOM   5205 O  O   . ASP B 1 229 ? 94.697  147.509 112.195 1.00 92.78  ? 229 ASP B O   1 
ATOM   5206 C  CB  . ASP B 1 229 ? 95.041  148.621 109.150 1.00 92.78  ? 229 ASP B CB  1 
ATOM   5207 C  CG  . ASP B 1 229 ? 96.206  148.420 108.225 1.00 92.78  ? 229 ASP B CG  1 
ATOM   5208 O  OD1 . ASP B 1 229 ? 96.763  147.305 108.212 1.00 92.78  ? 229 ASP B OD1 1 
ATOM   5209 O  OD2 . ASP B 1 229 ? 96.565  149.370 107.505 1.00 92.78  ? 229 ASP B OD2 1 
ATOM   5210 N  N   . MET B 1 230 ? 96.447  146.575 111.131 1.00 89.54  ? 230 MET B N   1 
ATOM   5211 C  CA  . MET B 1 230 ? 97.219  146.375 112.347 1.00 89.54  ? 230 MET B CA  1 
ATOM   5212 C  C   . MET B 1 230 ? 97.734  147.710 112.860 1.00 89.54  ? 230 MET B C   1 
ATOM   5213 O  O   . MET B 1 230 ? 98.260  148.523 112.098 1.00 89.54  ? 230 MET B O   1 
ATOM   5214 C  CB  . MET B 1 230 ? 98.382  145.418 112.084 1.00 89.54  ? 230 MET B CB  1 
ATOM   5215 C  CG  . MET B 1 230 ? 99.407  145.342 113.197 1.00 89.54  ? 230 MET B CG  1 
ATOM   5216 S  SD  . MET B 1 230 ? 100.719 144.145 112.923 1.00 89.54  ? 230 MET B SD  1 
ATOM   5217 C  CE  . MET B 1 230 ? 99.989  142.681 113.631 1.00 89.54  ? 230 MET B CE  1 
ATOM   5218 N  N   . THR B 1 231 ? 97.559  147.943 114.155 1.00 88.68  ? 231 THR B N   1 
ATOM   5219 C  CA  . THR B 1 231 ? 97.998  149.173 114.789 1.00 88.68  ? 231 THR B CA  1 
ATOM   5220 C  C   . THR B 1 231 ? 99.396  148.996 115.358 1.00 88.68  ? 231 THR B C   1 
ATOM   5221 O  O   . THR B 1 231 ? 100.004 147.930 115.258 1.00 88.68  ? 231 THR B O   1 
ATOM   5222 C  CB  . THR B 1 231 ? 97.031  149.595 115.894 1.00 88.68  ? 231 THR B CB  1 
ATOM   5223 O  OG1 . THR B 1 231 ? 97.159  148.708 117.005 1.00 88.68  ? 231 THR B OG1 1 
ATOM   5224 C  CG2 . THR B 1 231 ? 95.614  149.540 115.392 1.00 88.68  ? 231 THR B CG2 1 
ATOM   5225 N  N   . VAL B 1 232 ? 99.901  150.070 115.961 1.00 88.49  ? 232 VAL B N   1 
ATOM   5226 C  CA  . VAL B 1 232 ? 101.258 150.068 116.495 1.00 88.49  ? 232 VAL B CA  1 
ATOM   5227 C  C   . VAL B 1 232 ? 101.355 149.174 117.721 1.00 88.49  ? 232 VAL B C   1 
ATOM   5228 O  O   . VAL B 1 232 ? 102.325 148.428 117.885 1.00 88.49  ? 232 VAL B O   1 
ATOM   5229 C  CB  . VAL B 1 232 ? 101.697 151.506 116.807 1.00 88.49  ? 232 VAL B CB  1 
ATOM   5230 C  CG1 . VAL B 1 232 ? 103.126 151.533 117.261 1.00 88.49  ? 232 VAL B CG1 1 
ATOM   5231 C  CG2 . VAL B 1 232 ? 101.521 152.368 115.587 1.00 88.49  ? 232 VAL B CG2 1 
ATOM   5232 N  N   . GLU B 1 233 ? 100.343 149.222 118.588 1.00 90.63  ? 233 GLU B N   1 
ATOM   5233 C  CA  . GLU B 1 233 ? 100.373 148.451 119.826 1.00 90.63  ? 233 GLU B CA  1 
ATOM   5234 C  C   . GLU B 1 233 ? 100.258 146.960 119.551 1.00 90.63  ? 233 GLU B C   1 
ATOM   5235 O  O   . GLU B 1 233 ? 100.872 146.144 120.242 1.00 90.63  ? 233 GLU B O   1 
ATOM   5236 C  CB  . GLU B 1 233 ? 99.250  148.915 120.750 1.00 90.63  ? 233 GLU B CB  1 
ATOM   5237 C  CG  . GLU B 1 233 ? 99.371  150.361 121.182 1.00 90.63  ? 233 GLU B CG  1 
ATOM   5238 C  CD  . GLU B 1 233 ? 98.649  151.322 120.253 1.00 90.63  ? 233 GLU B CD  1 
ATOM   5239 O  OE1 . GLU B 1 233 ? 98.216  150.892 119.165 1.00 90.63  ? 233 GLU B OE1 1 
ATOM   5240 O  OE2 . GLU B 1 233 ? 98.523  152.511 120.606 1.00 90.63  ? 233 GLU B OE2 1 
ATOM   5241 N  N   . GLU B 1 234 ? 99.484  146.586 118.537 1.00 90.36  ? 234 GLU B N   1 
ATOM   5242 C  CA  . GLU B 1 234 ? 99.443  145.189 118.134 1.00 90.36  ? 234 GLU B CA  1 
ATOM   5243 C  C   . GLU B 1 234 ? 100.692 144.813 117.358 1.00 90.36  ? 234 GLU B C   1 
ATOM   5244 O  O   . GLU B 1 234 ? 101.065 143.637 117.300 1.00 90.36  ? 234 GLU B O   1 
ATOM   5245 C  CB  . GLU B 1 234 ? 98.197  144.922 117.299 1.00 90.36  ? 234 GLU B CB  1 
ATOM   5246 C  CG  . GLU B 1 234 ? 96.917  145.345 117.969 1.00 90.36  ? 234 GLU B CG  1 
ATOM   5247 C  CD  . GLU B 1 234 ? 95.870  145.793 116.980 1.00 90.36  ? 234 GLU B CD  1 
ATOM   5248 O  OE1 . GLU B 1 234 ? 96.151  145.776 115.765 1.00 90.36  ? 234 GLU B OE1 1 
ATOM   5249 O  OE2 . GLU B 1 234 ? 94.762  146.166 117.417 1.00 90.36  ? 234 GLU B OE2 1 
ATOM   5250 N  N   . GLY B 1 235 ? 101.348 145.797 116.746 1.00 87.81  ? 235 GLY B N   1 
ATOM   5251 C  CA  . GLY B 1 235 ? 102.558 145.510 116.001 1.00 87.81  ? 235 GLY B CA  1 
ATOM   5252 C  C   . GLY B 1 235 ? 103.788 145.476 116.882 1.00 87.81  ? 235 GLY B C   1 
ATOM   5253 O  O   . GLY B 1 235 ? 104.697 144.675 116.659 1.00 87.81  ? 235 GLY B O   1 
ATOM   5254 N  N   . ALA B 1 236 ? 103.842 146.350 117.888 1.00 85.94  ? 236 ALA B N   1 
ATOM   5255 C  CA  . ALA B 1 236 ? 104.977 146.347 118.802 1.00 85.94  ? 236 ALA B CA  1 
ATOM   5256 C  C   . ALA B 1 236 ? 104.942 145.132 119.708 1.00 85.94  ? 236 ALA B C   1 
ATOM   5257 O  O   . ALA B 1 236 ? 105.989 144.627 120.118 1.00 85.94  ? 236 ALA B O   1 
ATOM   5258 C  CB  . ALA B 1 236 ? 104.995 147.624 119.635 1.00 85.94  ? 236 ALA B CB  1 
ATOM   5259 N  N   . ALA B 1 237 ? 103.745 144.639 120.022 1.00 84.38  ? 237 ALA B N   1 
ATOM   5260 C  CA  . ALA B 1 237 ? 103.635 143.458 120.865 1.00 84.38  ? 237 ALA B CA  1 
ATOM   5261 C  C   . ALA B 1 237 ? 104.036 142.205 120.109 1.00 84.38  ? 237 ALA B C   1 
ATOM   5262 O  O   . ALA B 1 237 ? 104.369 141.188 120.720 1.00 84.38  ? 237 ALA B O   1 
ATOM   5263 C  CB  . ALA B 1 237 ? 102.216 143.324 121.401 1.00 84.38  ? 237 ALA B CB  1 
ATOM   5264 N  N   . ALA B 1 238 ? 104.002 142.251 118.781 1.00 82.58  ? 238 ALA B N   1 
ATOM   5265 C  CA  . ALA B 1 238 ? 104.462 141.116 117.996 1.00 82.58  ? 238 ALA B CA  1 
ATOM   5266 C  C   . ALA B 1 238 ? 105.978 141.027 118.009 1.00 82.58  ? 238 ALA B C   1 
ATOM   5267 O  O   . ALA B 1 238 ? 106.546 139.941 118.150 1.00 82.58  ? 238 ALA B O   1 
ATOM   5268 C  CB  . ALA B 1 238 ? 103.945 141.227 116.566 1.00 82.58  ? 238 ALA B CB  1 
ATOM   5269 N  N   . LEU B 1 239 ? 106.649 142.164 117.860 1.00 81.63  ? 239 LEU B N   1 
ATOM   5270 C  CA  . LEU B 1 239 ? 108.103 142.188 117.876 1.00 81.63  ? 239 LEU B CA  1 
ATOM   5271 C  C   . LEU B 1 239 ? 108.660 141.968 119.272 1.00 81.63  ? 239 LEU B C   1 
ATOM   5272 O  O   . LEU B 1 239 ? 109.698 141.319 119.422 1.00 81.63  ? 239 LEU B O   1 
ATOM   5273 C  CB  . LEU B 1 239 ? 108.603 143.512 117.310 1.00 81.63  ? 239 LEU B CB  1 
ATOM   5274 C  CG  . LEU B 1 239 ? 110.105 143.698 117.158 1.00 81.63  ? 239 LEU B CG  1 
ATOM   5275 C  CD1 . LEU B 1 239 ? 110.699 142.547 116.401 1.00 81.63  ? 239 LEU B CD1 1 
ATOM   5276 C  CD2 . LEU B 1 239 ? 110.381 144.990 116.443 1.00 81.63  ? 239 LEU B CD2 1 
ATOM   5277 N  N   . GLN B 1 240 ? 107.990 142.480 120.301 1.00 82.44  ? 240 GLN B N   1 
ATOM   5278 C  CA  . GLN B 1 240 ? 108.459 142.284 121.663 1.00 82.44  ? 240 GLN B CA  1 
ATOM   5279 C  C   . GLN B 1 240 ? 108.281 140.851 122.129 1.00 82.44  ? 240 GLN B C   1 
ATOM   5280 O  O   . GLN B 1 240 ? 109.055 140.371 122.960 1.00 82.44  ? 240 GLN B O   1 
ATOM   5281 C  CB  . GLN B 1 240 ? 107.730 143.231 122.606 1.00 82.44  ? 240 GLN B CB  1 
ATOM   5282 C  CG  . GLN B 1 240 ? 108.238 144.639 122.533 1.00 82.44  ? 240 GLN B CG  1 
ATOM   5283 C  CD  . GLN B 1 240 ? 107.346 145.602 123.252 1.00 82.44  ? 240 GLN B CD  1 
ATOM   5284 O  OE1 . GLN B 1 240 ? 106.533 145.208 124.079 1.00 82.44  ? 240 GLN B OE1 1 
ATOM   5285 N  NE2 . GLN B 1 240 ? 107.486 146.876 122.940 1.00 82.44  ? 240 GLN B NE2 1 
ATOM   5286 N  N   . ARG B 1 241 ? 107.274 140.157 121.613 1.00 81.86  ? 241 ARG B N   1 
ATOM   5287 C  CA  . ARG B 1 241 ? 107.101 138.745 121.911 1.00 81.86  ? 241 ARG B CA  1 
ATOM   5288 C  C   . ARG B 1 241 ? 108.191 137.905 121.268 1.00 81.86  ? 241 ARG B C   1 
ATOM   5289 O  O   . ARG B 1 241 ? 108.598 136.883 121.827 1.00 81.86  ? 241 ARG B O   1 
ATOM   5290 C  CB  . ARG B 1 241 ? 105.716 138.301 121.441 1.00 81.86  ? 241 ARG B CB  1 
ATOM   5291 C  CG  . ARG B 1 241 ? 105.417 136.830 121.487 1.00 81.86  ? 241 ARG B CG  1 
ATOM   5292 C  CD  . ARG B 1 241 ? 104.285 136.505 120.548 1.00 81.86  ? 241 ARG B CD  1 
ATOM   5293 N  NE  . ARG B 1 241 ? 104.712 136.567 119.158 1.00 81.86  ? 241 ARG B NE  1 
ATOM   5294 C  CZ  . ARG B 1 241 ? 103.983 137.084 118.179 1.00 81.86  ? 241 ARG B CZ  1 
ATOM   5295 N  NH1 . ARG B 1 241 ? 102.791 137.592 118.440 1.00 81.86  ? 241 ARG B NH1 1 
ATOM   5296 N  NH2 . ARG B 1 241 ? 104.447 137.098 116.940 1.00 81.86  ? 241 ARG B NH2 1 
ATOM   5297 N  N   . ASP B 1 242 ? 108.707 138.339 120.123 1.00 82.31  ? 242 ASP B N   1 
ATOM   5298 C  CA  . ASP B 1 242 ? 109.736 137.573 119.435 1.00 82.31  ? 242 ASP B CA  1 
ATOM   5299 C  C   . ASP B 1 242 ? 111.116 137.829 120.015 1.00 82.31  ? 242 ASP B C   1 
ATOM   5300 O  O   . ASP B 1 242 ? 111.985 136.957 119.950 1.00 82.31  ? 242 ASP B O   1 
ATOM   5301 C  CB  . ASP B 1 242 ? 109.714 137.899 117.947 1.00 82.31  ? 242 ASP B CB  1 
ATOM   5302 C  CG  . ASP B 1 242 ? 108.631 137.145 117.211 1.00 82.31  ? 242 ASP B CG  1 
ATOM   5303 O  OD1 . ASP B 1 242 ? 108.486 135.929 117.450 1.00 82.31  ? 242 ASP B OD1 1 
ATOM   5304 O  OD2 . ASP B 1 242 ? 107.918 137.764 116.395 1.00 82.31  ? 242 ASP B OD2 1 
ATOM   5305 N  N   . LEU B 1 243 ? 111.335 139.010 120.590 1.00 78.05  ? 243 LEU B N   1 
ATOM   5306 C  CA  . LEU B 1 243 ? 112.610 139.296 121.230 1.00 78.05  ? 243 LEU B CA  1 
ATOM   5307 C  C   . LEU B 1 243 ? 112.761 138.516 122.522 1.00 78.05  ? 243 LEU B C   1 
ATOM   5308 O  O   . LEU B 1 243 ? 113.875 138.159 122.913 1.00 78.05  ? 243 LEU B O   1 
ATOM   5309 C  CB  . LEU B 1 243 ? 112.731 140.786 121.504 1.00 78.05  ? 243 LEU B CB  1 
ATOM   5310 C  CG  . LEU B 1 243 ? 112.889 141.703 120.303 1.00 78.05  ? 243 LEU B CG  1 
ATOM   5311 C  CD1 . LEU B 1 243 ? 112.565 143.116 120.705 1.00 78.05  ? 243 LEU B CD1 1 
ATOM   5312 C  CD2 . LEU B 1 243 ? 114.290 141.620 119.775 1.00 78.05  ? 243 LEU B CD2 1 
ATOM   5313 N  N   . ARG B 1 244 ? 111.652 138.243 123.205 1.00 76.59  ? 244 ARG B N   1 
ATOM   5314 C  CA  . ARG B 1 244 ? 111.724 137.498 124.454 1.00 76.59  ? 244 ARG B CA  1 
ATOM   5315 C  C   . ARG B 1 244 ? 111.966 136.022 124.193 1.00 76.59  ? 244 ARG B C   1 
ATOM   5316 O  O   . ARG B 1 244 ? 112.646 135.350 124.972 1.00 76.59  ? 244 ARG B O   1 
ATOM   5317 C  CB  . ARG B 1 244 ? 110.445 137.700 125.257 1.00 76.59  ? 244 ARG B CB  1 
ATOM   5318 C  CG  . ARG B 1 244 ? 110.297 139.087 125.810 1.00 76.59  ? 244 ARG B CG  1 
ATOM   5319 C  CD  . ARG B 1 244 ? 109.519 139.073 127.094 1.00 76.59  ? 244 ARG B CD  1 
ATOM   5320 N  NE  . ARG B 1 244 ? 109.673 140.319 127.830 1.00 76.59  ? 244 ARG B NE  1 
ATOM   5321 C  CZ  . ARG B 1 244 ? 108.898 141.381 127.659 1.00 76.59  ? 244 ARG B CZ  1 
ATOM   5322 N  NH1 . ARG B 1 244 ? 107.914 141.348 126.774 1.00 76.59  ? 244 ARG B NH1 1 
ATOM   5323 N  NH2 . ARG B 1 244 ? 109.106 142.474 128.373 1.00 76.59  ? 244 ARG B NH2 1 
ATOM   5324 N  N   . LEU B 1 245 ? 111.414 135.498 123.103 1.00 74.91  ? 245 LEU B N   1 
ATOM   5325 C  CA  . LEU B 1 245 ? 111.651 134.103 122.762 1.00 74.91  ? 245 LEU B CA  1 
ATOM   5326 C  C   . LEU B 1 245 ? 113.060 133.902 122.224 1.00 74.91  ? 245 LEU B C   1 
ATOM   5327 O  O   . LEU B 1 245 ? 113.668 132.850 122.440 1.00 74.91  ? 245 LEU B O   1 
ATOM   5328 C  CB  . LEU B 1 245 ? 110.610 133.630 121.752 1.00 74.91  ? 245 LEU B CB  1 
ATOM   5329 C  CG  . LEU B 1 245 ? 110.704 132.195 121.252 1.00 74.91  ? 245 LEU B CG  1 
ATOM   5330 C  CD1 . LEU B 1 245 ? 110.594 131.243 122.405 1.00 74.91  ? 245 LEU B CD1 1 
ATOM   5331 C  CD2 . LEU B 1 245 ? 109.636 131.920 120.235 1.00 74.91  ? 245 LEU B CD2 1 
ATOM   5332 N  N   . ALA B 1 246 ? 113.606 134.903 121.539 1.00 74.93  ? 246 ALA B N   1 
ATOM   5333 C  CA  . ALA B 1 246 ? 114.976 134.786 121.061 1.00 74.93  ? 246 ALA B CA  1 
ATOM   5334 C  C   . ALA B 1 246 ? 115.974 134.957 122.192 1.00 74.93  ? 246 ALA B C   1 
ATOM   5335 O  O   . ALA B 1 246 ? 117.081 134.421 122.133 1.00 74.93  ? 246 ALA B O   1 
ATOM   5336 C  CB  . ALA B 1 246 ? 115.241 135.805 119.967 1.00 74.93  ? 246 ALA B CB  1 
ATOM   5337 N  N   . LYS B 1 247 ? 115.612 135.715 123.222 1.00 75.89  ? 247 LYS B N   1 
ATOM   5338 C  CA  . LYS B 1 247 ? 116.462 135.792 124.401 1.00 75.89  ? 247 LYS B CA  1 
ATOM   5339 C  C   . LYS B 1 247 ? 116.389 134.500 125.193 1.00 75.89  ? 247 LYS B C   1 
ATOM   5340 O  O   . LYS B 1 247 ? 117.380 134.070 125.792 1.00 75.89  ? 247 LYS B O   1 
ATOM   5341 C  CB  . LYS B 1 247 ? 116.048 136.983 125.261 1.00 75.89  ? 247 LYS B CB  1 
ATOM   5342 C  CG  . LYS B 1 247 ? 116.829 137.156 126.545 1.00 75.89  ? 247 LYS B CG  1 
ATOM   5343 C  CD  . LYS B 1 247 ? 118.311 137.236 126.275 1.00 75.89  ? 247 LYS B CD  1 
ATOM   5344 C  CE  . LYS B 1 247 ? 119.097 137.412 127.556 1.00 75.89  ? 247 LYS B CE  1 
ATOM   5345 N  NZ  . LYS B 1 247 ? 120.549 137.530 127.281 1.00 75.89  ? 247 LYS B NZ  1 
ATOM   5346 N  N   . ARG B 1 248 ? 115.226 133.855 125.181 1.00 73.39  ? 248 ARG B N   1 
ATOM   5347 C  CA  . ARG B 1 248 ? 115.038 132.629 125.940 1.00 73.39  ? 248 ARG B CA  1 
ATOM   5348 C  C   . ARG B 1 248 ? 115.819 131.479 125.328 1.00 73.39  ? 248 ARG B C   1 
ATOM   5349 O  O   . ARG B 1 248 ? 116.280 130.585 126.042 1.00 73.39  ? 248 ARG B O   1 
ATOM   5350 C  CB  . ARG B 1 248 ? 113.553 132.295 126.004 1.00 73.39  ? 248 ARG B CB  1 
ATOM   5351 C  CG  . ARG B 1 248 ? 113.188 131.227 126.991 1.00 73.39  ? 248 ARG B CG  1 
ATOM   5352 C  CD  . ARG B 1 248 ? 111.762 130.797 126.793 1.00 73.39  ? 248 ARG B CD  1 
ATOM   5353 N  NE  . ARG B 1 248 ? 111.462 129.586 127.537 1.00 73.39  ? 248 ARG B NE  1 
ATOM   5354 C  CZ  . ARG B 1 248 ? 110.322 128.920 127.437 1.00 73.39  ? 248 ARG B CZ  1 
ATOM   5355 N  NH1 . ARG B 1 248 ? 109.374 129.352 126.625 1.00 73.39  ? 248 ARG B NH1 1 
ATOM   5356 N  NH2 . ARG B 1 248 ? 110.131 127.824 128.150 1.00 73.39  ? 248 ARG B NH2 1 
ATOM   5357 N  N   . LEU B 1 249 ? 115.997 131.494 124.014 1.00 72.04  ? 249 LEU B N   1 
ATOM   5358 C  CA  . LEU B 1 249 ? 116.668 130.398 123.336 1.00 72.04  ? 249 LEU B CA  1 
ATOM   5359 C  C   . LEU B 1 249 ? 118.135 130.672 123.048 1.00 72.04  ? 249 LEU B C   1 
ATOM   5360 O  O   . LEU B 1 249 ? 118.814 129.792 122.520 1.00 72.04  ? 249 LEU B O   1 
ATOM   5361 C  CB  . LEU B 1 249 ? 115.940 130.071 122.036 1.00 72.04  ? 249 LEU B CB  1 
ATOM   5362 C  CG  . LEU B 1 249 ? 114.500 129.604 122.209 1.00 72.04  ? 249 LEU B CG  1 
ATOM   5363 C  CD1 . LEU B 1 249 ? 113.913 129.216 120.883 1.00 72.04  ? 249 LEU B CD1 1 
ATOM   5364 C  CD2 . LEU B 1 249 ? 114.437 128.446 123.163 1.00 72.04  ? 249 LEU B CD2 1 
ATOM   5365 N  N   . GLY B 1 250 ? 118.638 131.854 123.374 1.00 72.60  ? 250 GLY B N   1 
ATOM   5366 C  CA  . GLY B 1 250 ? 120.047 132.140 123.249 1.00 72.60  ? 250 GLY B CA  1 
ATOM   5367 C  C   . GLY B 1 250 ? 120.465 132.856 121.990 1.00 72.60  ? 250 GLY B C   1 
ATOM   5368 O  O   . GLY B 1 250 ? 121.667 133.010 121.763 1.00 72.60  ? 250 GLY B O   1 
ATOM   5369 N  N   . PHE B 1 251 ? 119.522 133.302 121.170 1.00 71.52  ? 251 PHE B N   1 
ATOM   5370 C  CA  . PHE B 1 251 ? 119.863 133.923 119.903 1.00 71.52  ? 251 PHE B CA  1 
ATOM   5371 C  C   . PHE B 1 251 ? 120.387 135.331 120.120 1.00 71.52  ? 251 PHE B C   1 
ATOM   5372 O  O   . PHE B 1 251 ? 120.146 135.952 121.153 1.00 71.52  ? 251 PHE B O   1 
ATOM   5373 C  CB  . PHE B 1 251 ? 118.648 133.956 118.988 1.00 71.52  ? 251 PHE B CB  1 
ATOM   5374 C  CG  . PHE B 1 251 ? 118.303 132.631 118.409 1.00 71.52  ? 251 PHE B CG  1 
ATOM   5375 C  CD1 . PHE B 1 251 ? 118.815 132.245 117.192 1.00 71.52  ? 251 PHE B CD1 1 
ATOM   5376 C  CD2 . PHE B 1 251 ? 117.475 131.765 119.083 1.00 71.52  ? 251 PHE B CD2 1 
ATOM   5377 C  CE1 . PHE B 1 251 ? 118.502 131.023 116.658 1.00 71.52  ? 251 PHE B CE1 1 
ATOM   5378 C  CE2 . PHE B 1 251 ? 117.166 130.544 118.555 1.00 71.52  ? 251 PHE B CE2 1 
ATOM   5379 C  CZ  . PHE B 1 251 ? 117.684 130.173 117.345 1.00 71.52  ? 251 PHE B CZ  1 
ATOM   5380 N  N   . ARG B 1 252 ? 121.119 135.832 119.130 1.00 75.56  ? 252 ARG B N   1 
ATOM   5381 C  CA  . ARG B 1 252 ? 121.708 137.159 119.216 1.00 75.56  ? 252 ARG B CA  1 
ATOM   5382 C  C   . ARG B 1 252 ? 121.062 138.169 118.290 1.00 75.56  ? 252 ARG B C   1 
ATOM   5383 O  O   . ARG B 1 252 ? 121.147 139.367 118.553 1.00 75.56  ? 252 ARG B O   1 
ATOM   5384 C  CB  . ARG B 1 252 ? 123.202 137.098 118.906 1.00 75.56  ? 252 ARG B CB  1 
ATOM   5385 C  CG  . ARG B 1 252 ? 123.907 135.945 119.556 1.00 75.56  ? 252 ARG B CG  1 
ATOM   5386 C  CD  . ARG B 1 252 ? 125.300 136.340 119.971 1.00 75.56  ? 252 ARG B CD  1 
ATOM   5387 N  NE  . ARG B 1 252 ? 125.995 137.066 118.915 1.00 75.56  ? 252 ARG B NE  1 
ATOM   5388 C  CZ  . ARG B 1 252 ? 126.714 136.488 117.961 1.00 75.56  ? 252 ARG B CZ  1 
ATOM   5389 N  NH1 . ARG B 1 252 ? 126.830 135.170 117.923 1.00 75.56  ? 252 ARG B NH1 1 
ATOM   5390 N  NH2 . ARG B 1 252 ? 127.316 137.228 117.043 1.00 75.56  ? 252 ARG B NH2 1 
ATOM   5391 N  N   . PHE B 1 253 ? 120.430 137.727 117.215 1.00 73.45  ? 253 PHE B N   1 
ATOM   5392 C  CA  . PHE B 1 253 ? 119.813 138.626 116.257 1.00 73.45  ? 253 PHE B CA  1 
ATOM   5393 C  C   . PHE B 1 253 ? 118.362 138.233 116.049 1.00 73.45  ? 253 PHE B C   1 
ATOM   5394 O  O   . PHE B 1 253 ? 118.020 137.050 116.108 1.00 73.45  ? 253 PHE B O   1 
ATOM   5395 C  CB  . PHE B 1 253 ? 120.541 138.605 114.916 1.00 73.45  ? 253 PHE B CB  1 
ATOM   5396 C  CG  . PHE B 1 253 ? 122.027 138.689 115.023 1.00 73.45  ? 253 PHE B CG  1 
ATOM   5397 C  CD1 . PHE B 1 253 ? 122.815 137.609 114.689 1.00 73.45  ? 253 PHE B CD1 1 
ATOM   5398 C  CD2 . PHE B 1 253 ? 122.639 139.853 115.435 1.00 73.45  ? 253 PHE B CD2 1 
ATOM   5399 C  CE1 . PHE B 1 253 ? 124.178 137.680 114.782 1.00 73.45  ? 253 PHE B CE1 1 
ATOM   5400 C  CE2 . PHE B 1 253 ? 124.005 139.929 115.526 1.00 73.45  ? 253 PHE B CE2 1 
ATOM   5401 C  CZ  . PHE B 1 253 ? 124.773 138.841 115.199 1.00 73.45  ? 253 PHE B CZ  1 
ATOM   5402 N  N   . VAL B 1 254 ? 117.515 139.228 115.804 1.00 74.26  ? 254 VAL B N   1 
ATOM   5403 C  CA  . VAL B 1 254 ? 116.123 139.021 115.428 1.00 74.26  ? 254 VAL B CA  1 
ATOM   5404 C  C   . VAL B 1 254 ? 115.896 139.752 114.119 1.00 74.26  ? 254 VAL B C   1 
ATOM   5405 O  O   . VAL B 1 254 ? 116.199 140.944 114.013 1.00 74.26  ? 254 VAL B O   1 
ATOM   5406 C  CB  . VAL B 1 254 ? 115.150 139.520 116.506 1.00 74.26  ? 254 VAL B CB  1 
ATOM   5407 C  CG1 . VAL B 1 254 ? 113.745 139.587 115.978 1.00 74.26  ? 254 VAL B CG1 1 
ATOM   5408 C  CG2 . VAL B 1 254 ? 115.165 138.606 117.653 1.00 74.26  ? 254 VAL B CG2 1 
ATOM   5409 N  N   . ARG B 1 255 ? 115.377 139.042 113.124 1.00 75.37  ? 255 ARG B N   1 
ATOM   5410 C  CA  . ARG B 1 255 ? 115.067 139.654 111.845 1.00 75.37  ? 255 ARG B CA  1 
ATOM   5411 C  C   . ARG B 1 255 ? 113.564 139.785 111.694 1.00 75.37  ? 255 ARG B C   1 
ATOM   5412 O  O   . ARG B 1 255 ? 112.894 138.782 111.420 1.00 75.37  ? 255 ARG B O   1 
ATOM   5413 C  CB  . ARG B 1 255 ? 115.646 138.829 110.703 1.00 75.37  ? 255 ARG B CB  1 
ATOM   5414 C  CG  . ARG B 1 255 ? 115.391 139.399 109.334 1.00 75.37  ? 255 ARG B CG  1 
ATOM   5415 C  CD  . ARG B 1 255 ? 114.890 138.338 108.390 1.00 75.37  ? 255 ARG B CD  1 
ATOM   5416 N  NE  . ARG B 1 255 ? 113.546 137.907 108.737 1.00 75.37  ? 255 ARG B NE  1 
ATOM   5417 C  CZ  . ARG B 1 255 ? 112.913 136.904 108.148 1.00 75.37  ? 255 ARG B CZ  1 
ATOM   5418 N  NH1 . ARG B 1 255 ? 113.504 136.229 107.180 1.00 75.37  ? 255 ARG B NH1 1 
ATOM   5419 N  NH2 . ARG B 1 255 ? 111.690 136.576 108.527 1.00 75.37  ? 255 ARG B NH2 1 
ATOM   5420 N  N   . PRO B 1 256 ? 112.989 140.966 111.875 1.00 75.17  ? 256 PRO B N   1 
ATOM   5421 C  CA  . PRO B 1 256 ? 111.552 141.122 111.643 1.00 75.17  ? 256 PRO B CA  1 
ATOM   5422 C  C   . PRO B 1 256 ? 111.222 141.419 110.192 1.00 75.17  ? 256 PRO B C   1 
ATOM   5423 O  O   . PRO B 1 256 ? 111.853 142.266 109.558 1.00 75.17  ? 256 PRO B O   1 
ATOM   5424 C  CB  . PRO B 1 256 ? 111.184 142.293 112.554 1.00 75.17  ? 256 PRO B CB  1 
ATOM   5425 C  CG  . PRO B 1 256 ? 112.411 143.075 112.668 1.00 75.17  ? 256 PRO B CG  1 
ATOM   5426 C  CD  . PRO B 1 256 ? 113.573 142.155 112.509 1.00 75.17  ? 256 PRO B CD  1 
ATOM   5427 N  N   . LYS B 1 257 ? 110.238 140.718 109.654 1.00 78.13  ? 257 LYS B N   1 
ATOM   5428 C  CA  . LYS B 1 257 ? 109.798 140.903 108.279 1.00 78.13  ? 257 LYS B CA  1 
ATOM   5429 C  C   . LYS B 1 257 ? 108.453 141.617 108.302 1.00 78.13  ? 257 LYS B C   1 
ATOM   5430 O  O   . LYS B 1 257 ? 107.423 141.000 108.570 1.00 78.13  ? 257 LYS B O   1 
ATOM   5431 C  CB  . LYS B 1 257 ? 109.705 139.559 107.565 1.00 78.13  ? 257 LYS B CB  1 
ATOM   5432 C  CG  . LYS B 1 257 ? 109.284 139.655 106.125 1.00 78.13  ? 257 LYS B CG  1 
ATOM   5433 C  CD  . LYS B 1 257 ? 110.335 140.344 105.289 1.00 78.13  ? 257 LYS B CD  1 
ATOM   5434 C  CE  . LYS B 1 257 ? 111.442 139.391 104.927 1.00 78.13  ? 257 LYS B CE  1 
ATOM   5435 N  NZ  . LYS B 1 257 ? 110.949 138.352 103.989 1.00 78.13  ? 257 LYS B NZ  1 
ATOM   5436 N  N   . ILE B 1 258 ? 108.468 142.915 108.029 1.00 80.88  ? 258 ILE B N   1 
ATOM   5437 C  CA  . ILE B 1 258 ? 107.276 143.750 108.089 1.00 80.88  ? 258 ILE B CA  1 
ATOM   5438 C  C   . ILE B 1 258 ? 106.504 143.606 106.781 1.00 80.88  ? 258 ILE B C   1 
ATOM   5439 O  O   . ILE B 1 258 ? 107.074 143.285 105.736 1.00 80.88  ? 258 ILE B O   1 
ATOM   5440 C  CB  . ILE B 1 258 ? 107.679 145.213 108.382 1.00 80.88  ? 258 ILE B CB  1 
ATOM   5441 C  CG1 . ILE B 1 258 ? 106.487 146.113 108.712 1.00 80.88  ? 258 ILE B CG1 1 
ATOM   5442 C  CG2 . ILE B 1 258 ? 108.482 145.798 107.239 1.00 80.88  ? 258 ILE B CG2 1 
ATOM   5443 C  CD1 . ILE B 1 258 ? 105.919 145.911 110.063 1.00 80.88  ? 258 ILE B CD1 1 
ATOM   5444 N  N   . GLY B 1 259 ? 105.187 143.796 106.837 1.00 84.69  ? 259 GLY B N   1 
ATOM   5445 C  CA  . GLY B 1 259 ? 104.388 143.774 105.635 1.00 84.69  ? 259 GLY B CA  1 
ATOM   5446 C  C   . GLY B 1 259 ? 104.531 145.035 104.808 1.00 84.69  ? 259 GLY B C   1 
ATOM   5447 O  O   . GLY B 1 259 ? 104.928 146.090 105.292 1.00 84.69  ? 259 GLY B O   1 
ATOM   5448 N  N   . VAL B 1 260 ? 104.186 144.919 103.532 1.00 89.02  ? 260 VAL B N   1 
ATOM   5449 C  CA  . VAL B 1 260 ? 104.397 145.986 102.565 1.00 89.02  ? 260 VAL B CA  1 
ATOM   5450 C  C   . VAL B 1 260 ? 103.057 146.566 102.143 1.00 89.02  ? 260 VAL B C   1 
ATOM   5451 O  O   . VAL B 1 260 ? 102.000 145.959 102.331 1.00 89.02  ? 260 VAL B O   1 
ATOM   5452 C  CB  . VAL B 1 260 ? 105.185 145.485 101.343 1.00 89.02  ? 260 VAL B CB  1 
ATOM   5453 C  CG1 . VAL B 1 260 ? 106.535 144.987 101.777 1.00 89.02  ? 260 VAL B CG1 1 
ATOM   5454 C  CG2 . VAL B 1 260 ? 104.425 144.387 100.647 1.00 89.02  ? 260 VAL B CG2 1 
ATOM   5455 N  N   . VAL B 1 261 ? 103.105 147.772 101.579 1.00 93.67  ? 261 VAL B N   1 
ATOM   5456 C  CA  . VAL B 1 261 ? 101.913 148.500 101.169 1.00 93.67  ? 261 VAL B CA  1 
ATOM   5457 C  C   . VAL B 1 261 ? 101.957 148.912 99.704  1.00 93.67  ? 261 VAL B C   1 
ATOM   5458 O  O   . VAL B 1 261 ? 101.059 149.610 99.239  1.00 93.67  ? 261 VAL B O   1 
ATOM   5459 C  CB  . VAL B 1 261 ? 101.670 149.738 102.055 1.00 93.67  ? 261 VAL B CB  1 
ATOM   5460 C  CG1 . VAL B 1 261 ? 101.465 149.351 103.493 1.00 93.67  ? 261 VAL B CG1 1 
ATOM   5461 C  CG2 . VAL B 1 261 ? 102.828 150.697 101.932 1.00 93.67  ? 261 VAL B CG2 1 
ATOM   5462 N  N   . SER B 1 262 ? 102.981 148.503 98.965  1.00 98.57  ? 262 SER B N   1 
ATOM   5463 C  CA  . SER B 1 262 ? 103.108 148.933 97.580  1.00 98.57  ? 262 SER B CA  1 
ATOM   5464 C  C   . SER B 1 262 ? 103.875 147.881 96.799  1.00 98.57  ? 262 SER B C   1 
ATOM   5465 O  O   . SER B 1 262 ? 104.360 146.895 97.353  1.00 98.57  ? 262 SER B O   1 
ATOM   5466 C  CB  . SER B 1 262 ? 103.811 150.284 97.477  1.00 98.57  ? 262 SER B CB  1 
ATOM   5467 O  OG  . SER B 1 262 ? 105.212 150.119 97.587  1.00 98.57  ? 262 SER B OG  1 
ATOM   5468 N  N   . SER B 1 263 ? 103.991 148.118 95.493  1.00 102.75 ? 263 SER B N   1 
ATOM   5469 C  CA  . SER B 1 263 ? 104.690 147.185 94.619  1.00 102.75 ? 263 SER B CA  1 
ATOM   5470 C  C   . SER B 1 263 ? 106.201 147.270 94.764  1.00 102.75 ? 263 SER B C   1 
ATOM   5471 O  O   . SER B 1 263 ? 106.899 146.323 94.394  1.00 102.75 ? 263 SER B O   1 
ATOM   5472 C  CB  . SER B 1 263 ? 104.300 147.438 93.166  1.00 102.75 ? 263 SER B CB  1 
ATOM   5473 O  OG  . SER B 1 263 ? 104.959 148.583 92.657  1.00 102.75 ? 263 SER B OG  1 
ATOM   5474 N  N   . ASP B 1 264 ? 106.721 148.372 95.297  1.00 102.97 ? 264 ASP B N   1 
ATOM   5475 C  CA  . ASP B 1 264 ? 108.154 148.561 95.456  1.00 102.97 ? 264 ASP B CA  1 
ATOM   5476 C  C   . ASP B 1 264 ? 108.671 148.009 96.774  1.00 102.97 ? 264 ASP B C   1 
ATOM   5477 O  O   . ASP B 1 264 ? 109.801 148.328 97.162  1.00 102.97 ? 264 ASP B O   1 
ATOM   5478 C  CB  . ASP B 1 264 ? 108.501 150.042 95.342  1.00 102.97 ? 264 ASP B CB  1 
ATOM   5479 C  CG  . ASP B 1 264 ? 108.298 150.578 93.945  1.00 102.97 ? 264 ASP B CG  1 
ATOM   5480 O  OD1 . ASP B 1 264 ? 108.464 149.801 92.982  1.00 102.97 ? 264 ASP B OD1 1 
ATOM   5481 O  OD2 . ASP B 1 264 ? 107.964 151.772 93.808  1.00 102.97 ? 264 ASP B OD2 1 
ATOM   5482 N  N   . LEU B 1 265 ? 107.860 147.187 97.455  1.00 97.91  ? 265 LEU B N   1 
ATOM   5483 C  CA  . LEU B 1 265 ? 108.131 146.643 98.790  1.00 97.91  ? 265 LEU B CA  1 
ATOM   5484 C  C   . LEU B 1 265 ? 108.415 147.749 99.800  1.00 97.91  ? 265 LEU B C   1 
ATOM   5485 O  O   . LEU B 1 265 ? 109.289 147.624 100.658 1.00 97.91  ? 265 LEU B O   1 
ATOM   5486 C  CB  . LEU B 1 265 ? 109.266 145.617 98.770  1.00 97.91  ? 265 LEU B CB  1 
ATOM   5487 C  CG  . LEU B 1 265 ? 109.159 144.438 97.806  1.00 97.91  ? 265 LEU B CG  1 
ATOM   5488 C  CD1 . LEU B 1 265 ? 110.210 143.414 98.161  1.00 97.91  ? 265 LEU B CD1 1 
ATOM   5489 C  CD2 . LEU B 1 265 ? 107.783 143.814 97.838  1.00 97.91  ? 265 LEU B CD2 1 
ATOM   5490 N  N   . ILE B 1 266 ? 107.681 148.849 99.678  1.00 97.04  ? 266 ILE B N   1 
ATOM   5491 C  CA  . ILE B 1 266 ? 107.745 149.900 100.694 1.00 97.04  ? 266 ILE B CA  1 
ATOM   5492 C  C   . ILE B 1 266 ? 107.118 149.370 101.971 1.00 97.04  ? 266 ILE B C   1 
ATOM   5493 O  O   . ILE B 1 266 ? 106.000 148.824 101.921 1.00 97.04  ? 266 ILE B O   1 
ATOM   5494 C  CB  . ILE B 1 266 ? 107.016 151.162 100.206 1.00 97.04  ? 266 ILE B CB  1 
ATOM   5495 C  CG1 . ILE B 1 266 ? 107.795 151.820 99.069  1.00 97.04  ? 266 ILE B CG1 1 
ATOM   5496 C  CG2 . ILE B 1 266 ? 106.807 152.144 101.339 1.00 97.04  ? 266 ILE B CG2 1 
ATOM   5497 C  CD1 . ILE B 1 266 ? 109.236 152.121 99.408  1.00 97.04  ? 266 ILE B CD1 1 
ATOM   5498 N  N   . PRO B 1 267 ? 107.790 149.461 103.118 1.00 92.55  ? 267 PRO B N   1 
ATOM   5499 C  CA  . PRO B 1 267 ? 107.242 148.884 104.348 1.00 92.55  ? 267 PRO B CA  1 
ATOM   5500 C  C   . PRO B 1 267 ? 105.995 149.612 104.820 1.00 92.55  ? 267 PRO B C   1 
ATOM   5501 O  O   . PRO B 1 267 ? 105.715 150.739 104.409 1.00 92.55  ? 267 PRO B O   1 
ATOM   5502 C  CB  . PRO B 1 267 ? 108.385 149.046 105.354 1.00 92.55  ? 267 PRO B CB  1 
ATOM   5503 C  CG  . PRO B 1 267 ? 109.595 149.242 104.532 1.00 92.55  ? 267 PRO B CG  1 
ATOM   5504 C  CD  . PRO B 1 267 ? 109.154 149.967 103.314 1.00 92.55  ? 267 PRO B CD  1 
ATOM   5505 N  N   . HIS B 1 268 ? 105.229 148.921 105.657 1.00 89.13  ? 268 HIS B N   1 
ATOM   5506 C  CA  . HIS B 1 268 ? 104.039 149.494 106.259 1.00 89.13  ? 268 HIS B CA  1 
ATOM   5507 C  C   . HIS B 1 268 ? 104.436 150.674 107.141 1.00 89.13  ? 268 HIS B C   1 
ATOM   5508 O  O   . HIS B 1 268 ? 105.497 150.642 107.766 1.00 89.13  ? 268 HIS B O   1 
ATOM   5509 C  CB  . HIS B 1 268 ? 103.320 148.428 107.080 1.00 89.13  ? 268 HIS B CB  1 
ATOM   5510 C  CG  . HIS B 1 268 ? 101.882 148.730 107.350 1.00 89.13  ? 268 HIS B CG  1 
ATOM   5511 N  ND1 . HIS B 1 268 ? 101.478 149.594 108.342 1.00 89.13  ? 268 HIS B ND1 1 
ATOM   5512 C  CD2 . HIS B 1 268 ? 100.752 148.262 106.777 1.00 89.13  ? 268 HIS B CD2 1 
ATOM   5513 C  CE1 . HIS B 1 268 ? 100.161 149.661 108.355 1.00 89.13  ? 268 HIS B CE1 1 
ATOM   5514 N  NE2 . HIS B 1 268 ? 99.695  148.862 107.415 1.00 89.13  ? 268 HIS B NE2 1 
ATOM   5515 N  N   . PRO B 1 269 ? 103.629 151.741 107.182 1.00 89.03  ? 269 PRO B N   1 
ATOM   5516 C  CA  . PRO B 1 269 ? 104.045 152.958 107.902 1.00 89.03  ? 269 PRO B CA  1 
ATOM   5517 C  C   . PRO B 1 269 ? 104.218 152.798 109.401 1.00 89.03  ? 269 PRO B C   1 
ATOM   5518 O  O   . PRO B 1 269 ? 104.854 153.650 110.030 1.00 89.03  ? 269 PRO B O   1 
ATOM   5519 C  CB  . PRO B 1 269 ? 102.914 153.940 107.586 1.00 89.03  ? 269 PRO B CB  1 
ATOM   5520 C  CG  . PRO B 1 269 ? 102.402 153.496 106.288 1.00 89.03  ? 269 PRO B CG  1 
ATOM   5521 C  CD  . PRO B 1 269 ? 102.498 152.009 106.280 1.00 89.03  ? 269 PRO B CD  1 
ATOM   5522 N  N   . ILE B 1 270 ? 103.697 151.726 109.996 1.00 88.94  ? 270 ILE B N   1 
ATOM   5523 C  CA  . ILE B 1 270 ? 103.822 151.547 111.432 1.00 88.94  ? 270 ILE B CA  1 
ATOM   5524 C  C   . ILE B 1 270 ? 105.200 151.058 111.848 1.00 88.94  ? 270 ILE B C   1 
ATOM   5525 O  O   . ILE B 1 270 ? 105.468 150.985 113.050 1.00 88.94  ? 270 ILE B O   1 
ATOM   5526 C  CB  . ILE B 1 270 ? 102.753 150.569 111.949 1.00 88.94  ? 270 ILE B CB  1 
ATOM   5527 C  CG1 . ILE B 1 270 ? 103.051 149.153 111.462 1.00 88.94  ? 270 ILE B CG1 1 
ATOM   5528 C  CG2 . ILE B 1 270 ? 101.380 150.999 111.504 1.00 88.94  ? 270 ILE B CG2 1 
ATOM   5529 C  CD1 . ILE B 1 270 ? 102.216 148.101 112.117 1.00 88.94  ? 270 ILE B CD1 1 
ATOM   5530 N  N   . TRP B 1 271 ? 106.084 150.730 110.895 1.00 90.86  ? 271 TRP B N   1 
ATOM   5531 C  CA  . TRP B 1 271 ? 107.310 150.001 111.222 1.00 90.86  ? 271 TRP B CA  1 
ATOM   5532 C  C   . TRP B 1 271 ? 108.275 150.849 112.036 1.00 90.86  ? 271 TRP B C   1 
ATOM   5533 O  O   . TRP B 1 271 ? 109.000 150.326 112.887 1.00 90.86  ? 271 TRP B O   1 
ATOM   5534 C  CB  . TRP B 1 271 ? 107.991 149.489 109.944 1.00 90.86  ? 271 TRP B CB  1 
ATOM   5535 C  CG  . TRP B 1 271 ? 108.847 150.500 109.217 1.00 90.86  ? 271 TRP B CG  1 
ATOM   5536 C  CD1 . TRP B 1 271 ? 108.456 151.325 108.207 1.00 90.86  ? 271 TRP B CD1 1 
ATOM   5537 C  CD2 . TRP B 1 271 ? 110.234 150.782 109.442 1.00 90.86  ? 271 TRP B CD2 1 
ATOM   5538 N  NE1 . TRP B 1 271 ? 109.501 152.109 107.797 1.00 90.86  ? 271 TRP B NE1 1 
ATOM   5539 C  CE2 . TRP B 1 271 ? 110.605 151.799 108.543 1.00 90.86  ? 271 TRP B CE2 1 
ATOM   5540 C  CE3 . TRP B 1 271 ? 111.191 150.288 110.330 1.00 90.86  ? 271 TRP B CE3 1 
ATOM   5541 C  CZ2 . TRP B 1 271 ? 111.889 152.319 108.498 1.00 90.86  ? 271 TRP B CZ2 1 
ATOM   5542 C  CZ3 . TRP B 1 271 ? 112.461 150.808 110.285 1.00 90.86  ? 271 TRP B CZ3 1 
ATOM   5543 C  CH2 . TRP B 1 271 ? 112.799 151.818 109.380 1.00 90.86  ? 271 TRP B CH2 1 
ATOM   5544 N  N   . THR B 1 272 ? 108.297 152.156 111.804 1.00 91.22  ? 272 THR B N   1 
ATOM   5545 C  CA  . THR B 1 272 ? 109.322 152.974 112.434 1.00 91.22  ? 272 THR B CA  1 
ATOM   5546 C  C   . THR B 1 272 ? 108.943 153.326 113.862 1.00 91.22  ? 272 THR B C   1 
ATOM   5547 O  O   . THR B 1 272 ? 109.787 153.769 114.643 1.00 91.22  ? 272 THR B O   1 
ATOM   5548 C  CB  . THR B 1 272 ? 109.589 154.226 111.603 1.00 91.22  ? 272 THR B CB  1 
ATOM   5549 O  OG1 . THR B 1 272 ? 110.657 154.971 112.197 1.00 91.22  ? 272 THR B OG1 1 
ATOM   5550 C  CG2 . THR B 1 272 ? 108.365 155.088 111.513 1.00 91.22  ? 272 THR B CG2 1 
ATOM   5551 N  N   . GLU B 1 273 ? 107.678 153.136 114.230 1.00 90.84  ? 273 GLU B N   1 
ATOM   5552 C  CA  . GLU B 1 273 ? 107.311 153.320 115.628 1.00 90.84  ? 273 GLU B CA  1 
ATOM   5553 C  C   . GLU B 1 273 ? 107.074 151.987 116.324 1.00 90.84  ? 273 GLU B C   1 
ATOM   5554 O  O   . GLU B 1 273 ? 106.967 151.937 117.553 1.00 90.84  ? 273 GLU B O   1 
ATOM   5555 C  CB  . GLU B 1 273 ? 106.094 154.231 115.748 1.00 90.84  ? 273 GLU B CB  1 
ATOM   5556 C  CG  . GLU B 1 273 ? 104.898 153.787 114.965 1.00 90.84  ? 273 GLU B CG  1 
ATOM   5557 C  CD  . GLU B 1 273 ? 104.709 154.584 113.695 1.00 90.84  ? 273 GLU B CD  1 
ATOM   5558 O  OE1 . GLU B 1 273 ? 105.644 155.304 113.300 1.00 90.84  ? 273 GLU B OE1 1 
ATOM   5559 O  OE2 . GLU B 1 273 ? 103.619 154.501 113.094 1.00 90.84  ? 273 GLU B OE2 1 
ATOM   5560 N  N   . VAL B 1 274 ? 106.986 150.896 115.565 1.00 87.95  ? 274 VAL B N   1 
ATOM   5561 C  CA  . VAL B 1 274 ? 107.019 149.568 116.171 1.00 87.95  ? 274 VAL B CA  1 
ATOM   5562 C  C   . VAL B 1 274 ? 108.435 149.239 116.624 1.00 87.95  ? 274 VAL B C   1 
ATOM   5563 O  O   . VAL B 1 274 ? 108.655 148.738 117.734 1.00 87.95  ? 274 VAL B O   1 
ATOM   5564 C  CB  . VAL B 1 274 ? 106.469 148.519 115.187 1.00 87.95  ? 274 VAL B CB  1 
ATOM   5565 C  CG1 . VAL B 1 274 ? 106.932 147.125 115.534 1.00 87.95  ? 274 VAL B CG1 1 
ATOM   5566 C  CG2 . VAL B 1 274 ? 104.973 148.551 115.194 1.00 87.95  ? 274 VAL B CG2 1 
ATOM   5567 N  N   . VAL B 1 275 ? 109.418 149.557 115.783 1.00 88.68  ? 275 VAL B N   1 
ATOM   5568 C  CA  . VAL B 1 275 ? 110.810 149.249 116.086 1.00 88.68  ? 275 VAL B CA  1 
ATOM   5569 C  C   . VAL B 1 275 ? 111.327 150.132 117.213 1.00 88.68  ? 275 VAL B C   1 
ATOM   5570 O  O   . VAL B 1 275 ? 111.990 149.651 118.137 1.00 88.68  ? 275 VAL B O   1 
ATOM   5571 C  CB  . VAL B 1 275 ? 111.657 149.379 114.807 1.00 88.68  ? 275 VAL B CB  1 
ATOM   5572 C  CG1 . VAL B 1 275 ? 113.122 149.554 115.121 1.00 88.68  ? 275 VAL B CG1 1 
ATOM   5573 C  CG2 . VAL B 1 275 ? 111.461 148.162 113.933 1.00 88.68  ? 275 VAL B CG2 1 
ATOM   5574 N  N   . GLU B 1 276 ? 110.990 151.419 117.193 1.00 92.28  ? 276 GLU B N   1 
ATOM   5575 C  CA  . GLU B 1 276 ? 111.496 152.323 118.219 1.00 92.28  ? 276 GLU B CA  1 
ATOM   5576 C  C   . GLU B 1 276 ? 110.821 152.093 119.563 1.00 92.28  ? 276 GLU B C   1 
ATOM   5577 O  O   . GLU B 1 276 ? 111.348 152.497 120.604 1.00 92.28  ? 276 GLU B O   1 
ATOM   5578 C  CB  . GLU B 1 276 ? 111.332 153.768 117.769 1.00 92.28  ? 276 GLU B CB  1 
ATOM   5579 C  CG  . GLU B 1 276 ? 112.291 154.144 116.667 1.00 92.28  ? 276 GLU B CG  1 
ATOM   5580 C  CD  . GLU B 1 276 ? 112.095 155.559 116.188 1.00 92.28  ? 276 GLU B CD  1 
ATOM   5581 O  OE1 . GLU B 1 276 ? 111.124 156.199 116.636 1.00 92.28  ? 276 GLU B OE1 1 
ATOM   5582 O  OE2 . GLU B 1 276 ? 112.905 156.031 115.363 1.00 92.28  ? 276 GLU B OE2 1 
ATOM   5583 N  N   . ALA B 1 277 ? 109.661 151.442 119.566 1.00 88.60  ? 277 ALA B N   1 
ATOM   5584 C  CA  . ALA B 1 277 ? 109.046 151.064 120.831 1.00 88.60  ? 277 ALA B CA  1 
ATOM   5585 C  C   . ALA B 1 277 ? 109.719 149.837 121.427 1.00 88.60  ? 277 ALA B C   1 
ATOM   5586 O  O   . ALA B 1 277 ? 109.684 149.631 122.645 1.00 88.60  ? 277 ALA B O   1 
ATOM   5587 C  CB  . ALA B 1 277 ? 107.555 150.812 120.635 1.00 88.60  ? 277 ALA B CB  1 
ATOM   5588 N  N   . SER B 1 278 ? 110.343 149.012 120.591 1.00 86.86  ? 278 SER B N   1 
ATOM   5589 C  CA  . SER B 1 278 ? 110.963 147.774 121.040 1.00 86.86  ? 278 SER B CA  1 
ATOM   5590 C  C   . SER B 1 278 ? 112.467 147.887 121.230 1.00 86.86  ? 278 SER B C   1 
ATOM   5591 O  O   . SER B 1 278 ? 113.089 146.933 121.701 1.00 86.86  ? 278 SER B O   1 
ATOM   5592 C  CB  . SER B 1 278 ? 110.662 146.654 120.052 1.00 86.86  ? 278 SER B CB  1 
ATOM   5593 O  OG  . SER B 1 278 ? 109.290 146.646 119.733 1.00 86.86  ? 278 SER B OG  1 
ATOM   5594 N  N   . LEU B 1 279 ? 113.065 149.014 120.864 1.00 87.32  ? 279 LEU B N   1 
ATOM   5595 C  CA  . LEU B 1 279 ? 114.480 149.228 121.151 1.00 87.32  ? 279 LEU B CA  1 
ATOM   5596 C  C   . LEU B 1 279 ? 114.822 149.349 122.637 1.00 87.32  ? 279 LEU B C   1 
ATOM   5597 O  O   . LEU B 1 279 ? 115.966 149.021 122.989 1.00 87.32  ? 279 LEU B O   1 
ATOM   5598 C  CB  . LEU B 1 279 ? 114.981 150.454 120.379 1.00 87.32  ? 279 LEU B CB  1 
ATOM   5599 C  CG  . LEU B 1 279 ? 115.221 150.235 118.890 1.00 87.32  ? 279 LEU B CG  1 
ATOM   5600 C  CD1 . LEU B 1 279 ? 115.714 151.501 118.245 1.00 87.32  ? 279 LEU B CD1 1 
ATOM   5601 C  CD2 . LEU B 1 279 ? 116.208 149.123 118.682 1.00 87.32  ? 279 LEU B CD2 1 
ATOM   5602 N  N   . PRO B 1 280 ? 113.951 149.836 123.540 1.00 87.39  ? 280 PRO B N   1 
ATOM   5603 C  CA  . PRO B 1 280 ? 114.239 149.624 124.968 1.00 87.39  ? 280 PRO B CA  1 
ATOM   5604 C  C   . PRO B 1 280 ? 114.313 148.167 125.395 1.00 87.39  ? 280 PRO B C   1 
ATOM   5605 O  O   . PRO B 1 280 ? 115.159 147.827 126.230 1.00 87.39  ? 280 PRO B O   1 
ATOM   5606 C  CB  . PRO B 1 280 ? 113.080 150.348 125.652 1.00 87.39  ? 280 PRO B CB  1 
ATOM   5607 C  CG  . PRO B 1 280 ? 112.829 151.467 124.789 1.00 87.39  ? 280 PRO B CG  1 
ATOM   5608 C  CD  . PRO B 1 280 ? 113.038 150.988 123.390 1.00 87.39  ? 280 PRO B CD  1 
ATOM   5609 N  N   . LEU B 1 281 ? 113.452 147.296 124.868 1.00 85.14  ? 281 LEU B N   1 
ATOM   5610 C  CA  . LEU B 1 281 ? 113.501 145.896 125.268 1.00 85.14  ? 281 LEU B CA  1 
ATOM   5611 C  C   . LEU B 1 281 ? 114.699 145.183 124.668 1.00 85.14  ? 281 LEU B C   1 
ATOM   5612 O  O   . LEU B 1 281 ? 115.248 144.268 125.288 1.00 85.14  ? 281 LEU B O   1 
ATOM   5613 C  CB  . LEU B 1 281 ? 112.213 145.182 124.867 1.00 85.14  ? 281 LEU B CB  1 
ATOM   5614 C  CG  . LEU B 1 281 ? 112.059 143.729 125.315 1.00 85.14  ? 281 LEU B CG  1 
ATOM   5615 C  CD1 . LEU B 1 281 ? 112.056 143.650 126.818 1.00 85.14  ? 281 LEU B CD1 1 
ATOM   5616 C  CD2 . LEU B 1 281 ? 110.815 143.104 124.754 1.00 85.14  ? 281 LEU B CD2 1 
ATOM   5617 N  N   . ALA B 1 282 ? 115.130 145.597 123.478 1.00 86.99  ? 282 ALA B N   1 
ATOM   5618 C  CA  . ALA B 1 282 ? 116.258 144.944 122.828 1.00 86.99  ? 282 ALA B CA  1 
ATOM   5619 C  C   . ALA B 1 282 ? 117.562 145.231 123.553 1.00 86.99  ? 282 ALA B C   1 
ATOM   5620 O  O   . ALA B 1 282 ? 118.420 144.353 123.660 1.00 86.99  ? 282 ALA B O   1 
ATOM   5621 C  CB  . ALA B 1 282 ? 116.349 145.392 121.373 1.00 86.99  ? 282 ALA B CB  1 
ATOM   5622 N  N   . GLU B 1 283 ? 117.719 146.446 124.075 1.00 91.54  ? 283 GLU B N   1 
ATOM   5623 C  CA  . GLU B 1 283 ? 118.949 146.796 124.771 1.00 91.54  ? 283 GLU B CA  1 
ATOM   5624 C  C   . GLU B 1 283 ? 119.008 146.138 126.138 1.00 91.54  ? 283 GLU B C   1 
ATOM   5625 O  O   . GLU B 1 283 ? 120.094 145.902 126.674 1.00 91.54  ? 283 GLU B O   1 
ATOM   5626 C  CB  . GLU B 1 283 ? 119.059 148.312 124.893 1.00 91.54  ? 283 GLU B CB  1 
ATOM   5627 C  CG  . GLU B 1 283 ? 119.183 149.014 123.550 1.00 91.54  ? 283 GLU B CG  1 
ATOM   5628 C  CD  . GLU B 1 283 ? 119.128 150.526 123.651 1.00 91.54  ? 283 GLU B CD  1 
ATOM   5629 O  OE1 . GLU B 1 283 ? 118.893 151.045 124.762 1.00 91.54  ? 283 GLU B OE1 1 
ATOM   5630 O  OE2 . GLU B 1 283 ? 119.302 151.197 122.611 1.00 91.54  ? 283 GLU B OE2 1 
ATOM   5631 N  N   . GLU B 1 284 ? 117.850 145.826 126.715 1.00 90.95  ? 284 GLU B N   1 
ATOM   5632 C  CA  . GLU B 1 284 ? 117.832 145.156 128.009 1.00 90.95  ? 284 GLU B CA  1 
ATOM   5633 C  C   . GLU B 1 284 ? 118.153 143.674 127.866 1.00 90.95  ? 284 GLU B C   1 
ATOM   5634 O  O   . GLU B 1 284 ? 118.934 143.121 128.647 1.00 90.95  ? 284 GLU B O   1 
ATOM   5635 C  CB  . GLU B 1 284 ? 116.474 145.359 128.673 1.00 90.95  ? 284 GLU B CB  1 
ATOM   5636 C  CG  . GLU B 1 284 ? 116.234 144.479 129.870 1.00 90.95  ? 284 GLU B CG  1 
ATOM   5637 C  CD  . GLU B 1 284 ? 114.768 144.288 130.151 1.00 90.95  ? 284 GLU B CD  1 
ATOM   5638 O  OE1 . GLU B 1 284 ? 114.004 145.261 129.998 1.00 90.95  ? 284 GLU B OE1 1 
ATOM   5639 O  OE2 . GLU B 1 284 ? 114.378 143.163 130.520 1.00 90.95  ? 284 GLU B OE2 1 
ATOM   5640 N  N   . LEU B 1 285 ? 117.579 143.018 126.862 1.00 85.57  ? 285 LEU B N   1 
ATOM   5641 C  CA  . LEU B 1 285 ? 117.850 141.610 126.620 1.00 85.57  ? 285 LEU B CA  1 
ATOM   5642 C  C   . LEU B 1 285 ? 119.119 141.369 125.816 1.00 85.57  ? 285 LEU B C   1 
ATOM   5643 O  O   . LEU B 1 285 ? 119.527 140.210 125.696 1.00 85.57  ? 285 LEU B O   1 
ATOM   5644 C  CB  . LEU B 1 285 ? 116.678 140.971 125.886 1.00 85.57  ? 285 LEU B CB  1 
ATOM   5645 C  CG  . LEU B 1 285 ? 115.303 141.132 126.505 1.00 85.57  ? 285 LEU B CG  1 
ATOM   5646 C  CD1 . LEU B 1 285 ? 114.300 140.361 125.695 1.00 85.57  ? 285 LEU B CD1 1 
ATOM   5647 C  CD2 . LEU B 1 285 ? 115.309 140.646 127.927 1.00 85.57  ? 285 LEU B CD2 1 
ATOM   5648 N  N   . ASP B 1 286 ? 119.728 142.428 125.268 1.00 87.46  ? 286 ASP B N   1 
ATOM   5649 C  CA  . ASP B 1 286 ? 120.932 142.368 124.426 1.00 87.46  ? 286 ASP B CA  1 
ATOM   5650 C  C   . ASP B 1 286 ? 120.711 141.480 123.201 1.00 87.46  ? 286 ASP B C   1 
ATOM   5651 O  O   . ASP B 1 286 ? 121.420 140.503 122.971 1.00 87.46  ? 286 ASP B O   1 
ATOM   5652 C  CB  . ASP B 1 286 ? 122.160 141.912 125.220 1.00 87.46  ? 286 ASP B CB  1 
ATOM   5653 C  CG  . ASP B 1 286 ? 123.459 142.393 124.614 1.00 87.46  ? 286 ASP B CG  1 
ATOM   5654 O  OD1 . ASP B 1 286 ? 124.058 143.323 125.186 1.00 87.46  ? 286 ASP B OD1 1 
ATOM   5655 O  OD2 . ASP B 1 286 ? 123.871 141.878 123.558 1.00 87.46  ? 286 ASP B OD2 1 
ATOM   5656 N  N   . VAL B 1 287 ? 119.683 141.810 122.431 1.00 82.45  ? 287 VAL B N   1 
ATOM   5657 C  CA  . VAL B 1 287 ? 119.416 141.192 121.141 1.00 82.45  ? 287 VAL B CA  1 
ATOM   5658 C  C   . VAL B 1 287 ? 119.381 142.308 120.112 1.00 82.45  ? 287 VAL B C   1 
ATOM   5659 O  O   . VAL B 1 287 ? 118.795 143.365 120.356 1.00 82.45  ? 287 VAL B O   1 
ATOM   5660 C  CB  . VAL B 1 287 ? 118.093 140.396 121.142 1.00 82.45  ? 287 VAL B CB  1 
ATOM   5661 C  CG1 . VAL B 1 287 ? 117.936 139.644 119.863 1.00 82.45  ? 287 VAL B CG1 1 
ATOM   5662 C  CG2 . VAL B 1 287 ? 118.054 139.421 122.282 1.00 82.45  ? 287 VAL B CG2 1 
ATOM   5663 N  N   . ILE B 1 288 ? 120.027 142.095 118.980 1.00 79.17  ? 288 ILE B N   1 
ATOM   5664 C  CA  . ILE B 1 288 ? 120.098 143.098 117.929 1.00 79.17  ? 288 ILE B CA  1 
ATOM   5665 C  C   . ILE B 1 288 ? 118.946 142.870 116.963 1.00 79.17  ? 288 ILE B C   1 
ATOM   5666 O  O   . ILE B 1 288 ? 118.688 141.736 116.548 1.00 79.17  ? 288 ILE B O   1 
ATOM   5667 C  CB  . ILE B 1 288 ? 121.459 143.045 117.216 1.00 79.17  ? 288 ILE B CB  1 
ATOM   5668 C  CG1 . ILE B 1 288 ? 122.567 143.298 118.226 1.00 79.17  ? 288 ILE B CG1 1 
ATOM   5669 C  CG2 . ILE B 1 288 ? 121.540 144.071 116.116 1.00 79.17  ? 288 ILE B CG2 1 
ATOM   5670 C  CD1 . ILE B 1 288 ? 123.929 143.010 117.707 1.00 79.17  ? 288 ILE B CD1 1 
ATOM   5671 N  N   . ILE B 1 289 ? 118.231 143.940 116.633 1.00 79.64  ? 289 ILE B N   1 
ATOM   5672 C  CA  . ILE B 1 289 ? 117.177 143.897 115.627 1.00 79.64  ? 289 ILE B CA  1 
ATOM   5673 C  C   . ILE B 1 289 ? 117.806 144.199 114.276 1.00 79.64  ? 289 ILE B C   1 
ATOM   5674 O  O   . ILE B 1 289 ? 118.443 145.240 114.105 1.00 79.64  ? 289 ILE B O   1 
ATOM   5675 C  CB  . ILE B 1 289 ? 116.063 144.903 115.945 1.00 79.64  ? 289 ILE B CB  1 
ATOM   5676 C  CG1 . ILE B 1 289 ? 115.473 144.641 117.322 1.00 79.64  ? 289 ILE B CG1 1 
ATOM   5677 C  CG2 . ILE B 1 289 ? 114.979 144.839 114.905 1.00 79.64  ? 289 ILE B CG2 1 
ATOM   5678 C  CD1 . ILE B 1 289 ? 114.497 145.683 117.750 1.00 79.64  ? 289 ILE B CD1 1 
ATOM   5679 N  N   . CYS B 1 290 ? 117.637 143.302 113.313 1.00 81.05  ? 290 CYS B N   1 
ATOM   5680 C  CA  . CYS B 1 290 ? 118.233 143.476 111.991 1.00 81.05  ? 290 CYS B CA  1 
ATOM   5681 C  C   . CYS B 1 290 ? 117.256 143.120 110.878 1.00 81.05  ? 290 CYS B C   1 
ATOM   5682 O  O   . CYS B 1 290 ? 117.043 141.926 110.595 1.00 81.05  ? 290 CYS B O   1 
ATOM   5683 C  CB  . CYS B 1 290 ? 119.531 142.675 111.889 1.00 81.05  ? 290 CYS B CB  1 
ATOM   5684 S  SG  . CYS B 1 290 ? 119.476 140.921 112.307 1.00 81.05  ? 290 CYS B SG  1 
ATOM   5685 N  N   . PRO B 1 291 ? 116.646 144.101 110.224 1.00 82.08  ? 291 PRO B N   1 
ATOM   5686 C  CA  . PRO B 1 291 ? 115.787 143.798 109.077 1.00 82.08  ? 291 PRO B CA  1 
ATOM   5687 C  C   . PRO B 1 291 ? 116.598 143.380 107.861 1.00 82.08  ? 291 PRO B C   1 
ATOM   5688 O  O   . PRO B 1 291 ? 117.767 143.737 107.714 1.00 82.08  ? 291 PRO B O   1 
ATOM   5689 C  CB  . PRO B 1 291 ? 115.052 145.116 108.834 1.00 82.08  ? 291 PRO B CB  1 
ATOM   5690 C  CG  . PRO B 1 291 ? 115.923 146.133 109.433 1.00 82.08  ? 291 PRO B CG  1 
ATOM   5691 C  CD  . PRO B 1 291 ? 116.555 145.509 110.616 1.00 82.08  ? 291 PRO B CD  1 
ATOM   5692 N  N   . GLU B 1 292 ? 115.955 142.626 106.979 1.00 85.94  ? 292 GLU B N   1 
ATOM   5693 C  CA  . GLU B 1 292 ? 116.643 141.985 105.869 1.00 85.94  ? 292 GLU B CA  1 
ATOM   5694 C  C   . GLU B 1 292 ? 116.687 142.893 104.647 1.00 85.94  ? 292 GLU B C   1 
ATOM   5695 O  O   . GLU B 1 292 ? 115.701 143.548 104.306 1.00 85.94  ? 292 GLU B O   1 
ATOM   5696 C  CB  . GLU B 1 292 ? 115.943 140.672 105.527 1.00 85.94  ? 292 GLU B CB  1 
ATOM   5697 C  CG  . GLU B 1 292 ? 116.663 139.783 104.549 1.00 85.94  ? 292 GLU B CG  1 
ATOM   5698 C  CD  . GLU B 1 292 ? 115.861 138.547 104.218 1.00 85.94  ? 292 GLU B CD  1 
ATOM   5699 O  OE1 . GLU B 1 292 ? 114.662 138.519 104.547 1.00 85.94  ? 292 GLU B OE1 1 
ATOM   5700 O  OE2 . GLU B 1 292 ? 116.418 137.601 103.630 1.00 85.94  ? 292 GLU B OE2 1 
ATOM   5701 N  N   . ILE B 1 293 ? 117.843 142.930 103.992 1.00 87.35  ? 293 ILE B N   1 
ATOM   5702 C  CA  . ILE B 1 293 ? 118.029 143.634 102.730 1.00 87.35  ? 293 ILE B CA  1 
ATOM   5703 C  C   . ILE B 1 293 ? 118.132 142.573 101.646 1.00 87.35  ? 293 ILE B C   1 
ATOM   5704 O  O   . ILE B 1 293 ? 119.190 141.970 101.454 1.00 87.35  ? 293 ILE B O   1 
ATOM   5705 C  CB  . ILE B 1 293 ? 119.275 144.526 102.751 1.00 87.35  ? 293 ILE B CB  1 
ATOM   5706 C  CG1 . ILE B 1 293 ? 119.219 145.509 103.915 1.00 87.35  ? 293 ILE B CG1 1 
ATOM   5707 C  CG2 . ILE B 1 293 ? 119.414 145.272 101.447 1.00 87.35  ? 293 ILE B CG2 1 
ATOM   5708 C  CD1 . ILE B 1 293 ? 117.959 146.322 103.968 1.00 87.35  ? 293 ILE B CD1 1 
ATOM   5709 N  N   . HIS B 1 294 ? 117.040 142.339 100.930 1.00 90.92  ? 294 HIS B N   1 
ATOM   5710 C  CA  . HIS B 1 294 ? 116.962 141.247 99.976  1.00 90.92  ? 294 HIS B CA  1 
ATOM   5711 C  C   . HIS B 1 294 ? 116.379 141.750 98.667  1.00 90.92  ? 294 HIS B C   1 
ATOM   5712 O  O   . HIS B 1 294 ? 115.707 142.778 98.620  1.00 90.92  ? 294 HIS B O   1 
ATOM   5713 C  CB  . HIS B 1 294 ? 116.120 140.087 100.516 1.00 90.92  ? 294 HIS B CB  1 
ATOM   5714 C  CG  . HIS B 1 294 ? 114.689 140.444 100.766 1.00 90.92  ? 294 HIS B CG  1 
ATOM   5715 N  ND1 . HIS B 1 294 ? 113.646 139.843 100.098 1.00 90.92  ? 294 HIS B ND1 1 
ATOM   5716 C  CD2 . HIS B 1 294 ? 114.126 141.339 101.611 1.00 90.92  ? 294 HIS B CD2 1 
ATOM   5717 C  CE1 . HIS B 1 294 ? 112.504 140.355 100.518 1.00 90.92  ? 294 HIS B CE1 1 
ATOM   5718 N  NE2 . HIS B 1 294 ? 112.768 141.265 101.436 1.00 90.92  ? 294 HIS B NE2 1 
ATOM   5719 N  N   . SER B 1 295 ? 116.648 140.995 97.609  1.00 94.54  ? 295 SER B N   1 
ATOM   5720 C  CA  . SER B 1 295 ? 116.206 141.347 96.268  1.00 94.54  ? 295 SER B CA  1 
ATOM   5721 C  C   . SER B 1 295 ? 114.683 141.310 96.189  1.00 94.54  ? 295 SER B C   1 
ATOM   5722 O  O   . SER B 1 295 ? 114.063 140.430 96.797  1.00 94.54  ? 295 SER B O   1 
ATOM   5723 C  CB  . SER B 1 295 ? 116.820 140.366 95.273  1.00 94.54  ? 295 SER B CB  1 
ATOM   5724 O  OG  . SER B 1 295 ? 116.422 140.626 93.946  1.00 94.54  ? 295 SER B OG  1 
ATOM   5725 N  N   . PRO B 1 296 ? 114.040 142.226 95.451  1.00 95.49  ? 296 PRO B N   1 
ATOM   5726 C  CA  . PRO B 1 296 ? 114.528 143.235 94.510  1.00 95.49  ? 296 PRO B CA  1 
ATOM   5727 C  C   . PRO B 1 296 ? 114.990 144.555 95.095  1.00 95.49  ? 296 PRO B C   1 
ATOM   5728 O  O   . PRO B 1 296 ? 115.092 145.505 94.333  1.00 95.49  ? 296 PRO B O   1 
ATOM   5729 C  CB  . PRO B 1 296 ? 113.309 143.479 93.636  1.00 95.49  ? 296 PRO B CB  1 
ATOM   5730 C  CG  . PRO B 1 296 ? 112.194 143.330 94.563  1.00 95.49  ? 296 PRO B CG  1 
ATOM   5731 C  CD  . PRO B 1 296 ? 112.571 142.216 95.491  1.00 95.49  ? 296 PRO B CD  1 
ATOM   5732 N  N   . THR B 1 297 ? 115.248 144.636 96.390  1.00 95.63  ? 297 THR B N   1 
ATOM   5733 C  CA  . THR B 1 297 ? 115.752 145.877 96.963  1.00 95.63  ? 297 THR B CA  1 
ATOM   5734 C  C   . THR B 1 297 ? 117.272 145.906 96.874  1.00 95.63  ? 297 THR B C   1 
ATOM   5735 O  O   . THR B 1 297 ? 117.931 145.057 97.479  1.00 95.63  ? 297 THR B O   1 
ATOM   5736 C  CB  . THR B 1 297 ? 115.321 146.019 98.412  1.00 95.63  ? 297 THR B CB  1 
ATOM   5737 O  OG1 . THR B 1 297 ? 113.895 145.961 98.495  1.00 95.63  ? 297 THR B OG1 1 
ATOM   5738 C  CG2 . THR B 1 297 ? 115.803 147.330 98.980  1.00 95.63  ? 297 THR B CG2 1 
ATOM   5739 N  N   . PRO B 1 298 ? 117.864 146.841 96.143  1.00 97.65  ? 298 PRO B N   1 
ATOM   5740 C  CA  . PRO B 1 298 ? 119.319 146.973 96.153  1.00 97.65  ? 298 PRO B CA  1 
ATOM   5741 C  C   . PRO B 1 298 ? 119.789 147.707 97.399  1.00 97.65  ? 298 PRO B C   1 
ATOM   5742 O  O   . PRO B 1 298 ? 119.001 148.129 98.242  1.00 97.65  ? 298 PRO B O   1 
ATOM   5743 C  CB  . PRO B 1 298 ? 119.601 147.787 94.892  1.00 97.65  ? 298 PRO B CB  1 
ATOM   5744 C  CG  . PRO B 1 298 ? 118.400 148.621 94.738  1.00 97.65  ? 298 PRO B CG  1 
ATOM   5745 C  CD  . PRO B 1 298 ? 117.238 147.814 95.235  1.00 97.65  ? 298 PRO B CD  1 
ATOM   5746 N  N   . ILE B 1 299 ? 121.108 147.855 97.502  1.00 97.66  ? 299 ILE B N   1 
ATOM   5747 C  CA  . ILE B 1 299 ? 121.677 148.563 98.644  1.00 97.66  ? 299 ILE B CA  1 
ATOM   5748 C  C   . ILE B 1 299 ? 121.435 150.061 98.508  1.00 97.66  ? 299 ILE B C   1 
ATOM   5749 O  O   . ILE B 1 299 ? 121.080 150.741 99.479  1.00 97.66  ? 299 ILE B O   1 
ATOM   5750 C  CB  . ILE B 1 299 ? 123.171 148.216 98.784  1.00 97.66  ? 299 ILE B CB  1 
ATOM   5751 C  CG1 . ILE B 1 299 ? 123.321 146.794 99.312  1.00 97.66  ? 299 ILE B CG1 1 
ATOM   5752 C  CG2 . ILE B 1 299 ? 123.881 149.160 99.727  1.00 97.66  ? 299 ILE B CG2 1 
ATOM   5753 C  CD1 . ILE B 1 299 ? 124.736 146.305 99.345  1.00 97.66  ? 299 ILE B CD1 1 
ATOM   5754 N  N   . LYS B 1 300 ? 121.566 150.589 97.291  1.00 99.97  ? 300 LYS B N   1 
ATOM   5755 C  CA  . LYS B 1 300 ? 121.309 152.003 97.019  1.00 99.97  ? 300 LYS B CA  1 
ATOM   5756 C  C   . LYS B 1 300 ? 119.805 152.209 96.866  1.00 99.97  ? 300 LYS B C   1 
ATOM   5757 O  O   . LYS B 1 300 ? 119.278 152.388 95.768  1.00 99.97  ? 300 LYS B O   1 
ATOM   5758 C  CB  . LYS B 1 300 ? 122.053 152.446 95.768  1.00 99.97  ? 300 LYS B CB  1 
ATOM   5759 C  CG  . LYS B 1 300 ? 123.522 152.106 95.743  1.00 99.97  ? 300 LYS B CG  1 
ATOM   5760 C  CD  . LYS B 1 300 ? 124.333 153.104 96.526  1.00 99.97  ? 300 LYS B CD  1 
ATOM   5761 C  CE  . LYS B 1 300 ? 125.808 152.921 96.238  1.00 99.97  ? 300 LYS B CE  1 
ATOM   5762 N  NZ  . LYS B 1 300 ? 126.119 153.219 94.814  1.00 99.97  ? 300 LYS B NZ  1 
ATOM   5763 N  N   . HIS B 1 301 ? 119.103 152.193 97.993  1.00 100.85 ? 301 HIS B N   1 
ATOM   5764 C  CA  . HIS B 1 301 ? 117.652 152.277 97.979  1.00 100.85 ? 301 HIS B CA  1 
ATOM   5765 C  C   . HIS B 1 301 ? 117.179 153.171 99.113  1.00 100.85 ? 301 HIS B C   1 
ATOM   5766 O  O   . HIS B 1 301 ? 117.892 153.402 100.089 1.00 100.85 ? 301 HIS B O   1 
ATOM   5767 C  CB  . HIS B 1 301 ? 117.014 150.890 98.089  1.00 100.85 ? 301 HIS B CB  1 
ATOM   5768 C  CG  . HIS B 1 301 ? 115.604 150.834 97.596  1.00 100.85 ? 301 HIS B CG  1 
ATOM   5769 N  ND1 . HIS B 1 301 ? 114.520 150.992 98.430  1.00 100.85 ? 301 HIS B ND1 1 
ATOM   5770 C  CD2 . HIS B 1 301 ? 115.100 150.644 96.356  1.00 100.85 ? 301 HIS B CD2 1 
ATOM   5771 C  CE1 . HIS B 1 301 ? 113.408 150.897 97.725  1.00 100.85 ? 301 HIS B CE1 1 
ATOM   5772 N  NE2 . HIS B 1 301 ? 113.732 150.686 96.463  1.00 100.85 ? 301 HIS B NE2 1 
ATOM   5773 N  N   . GLU B 1 302 ? 115.955 153.676 98.964  1.00 102.54 ? 302 GLU B N   1 
ATOM   5774 C  CA  . GLU B 1 302 ? 115.392 154.584 99.955  1.00 102.54 ? 302 GLU B CA  1 
ATOM   5775 C  C   . GLU B 1 302 ? 114.996 153.841 101.222 1.00 102.54 ? 302 GLU B C   1 
ATOM   5776 O  O   . GLU B 1 302 ? 114.995 154.420 102.314 1.00 102.54 ? 302 GLU B O   1 
ATOM   5777 C  CB  . GLU B 1 302 ? 114.182 155.311 99.370  1.00 102.54 ? 302 GLU B CB  1 
ATOM   5778 C  CG  . GLU B 1 302 ? 114.501 156.268 98.228  1.00 102.54 ? 302 GLU B CG  1 
ATOM   5779 C  CD  . GLU B 1 302 ? 114.555 155.587 96.869  1.00 102.54 ? 302 GLU B CD  1 
ATOM   5780 O  OE1 . GLU B 1 302 ? 114.283 154.371 96.796  1.00 102.54 ? 302 GLU B OE1 1 
ATOM   5781 O  OE2 . GLU B 1 302 ? 114.874 156.269 95.874  1.00 102.54 ? 302 GLU B OE2 1 
ATOM   5782 N  N   . VAL B 1 303 ? 114.638 152.564 101.089 1.00 98.50  ? 303 VAL B N   1 
ATOM   5783 C  CA  . VAL B 1 303 ? 114.286 151.748 102.246 1.00 98.50  ? 303 VAL B CA  1 
ATOM   5784 C  C   . VAL B 1 303 ? 115.514 151.503 103.110 1.00 98.50  ? 303 VAL B C   1 
ATOM   5785 O  O   . VAL B 1 303 ? 115.454 151.586 104.342 1.00 98.50  ? 303 VAL B O   1 
ATOM   5786 C  CB  . VAL B 1 303 ? 113.639 150.433 101.770 1.00 98.50  ? 303 VAL B CB  1 
ATOM   5787 C  CG1 . VAL B 1 303 ? 113.567 149.403 102.877 1.00 98.50  ? 303 VAL B CG1 1 
ATOM   5788 C  CG2 . VAL B 1 303 ? 112.263 150.705 101.215 1.00 98.50  ? 303 VAL B CG2 1 
ATOM   5789 N  N   . VAL B 1 304 ? 116.656 151.252 102.471 1.00 96.97  ? 304 VAL B N   1 
ATOM   5790 C  CA  . VAL B 1 304 ? 117.886 150.961 103.195 1.00 96.97  ? 304 VAL B CA  1 
ATOM   5791 C  C   . VAL B 1 304 ? 118.402 152.208 103.895 1.00 96.97  ? 304 VAL B C   1 
ATOM   5792 O  O   . VAL B 1 304 ? 118.905 152.138 105.019 1.00 96.97  ? 304 VAL B O   1 
ATOM   5793 C  CB  . VAL B 1 304 ? 118.920 150.373 102.221 1.00 96.97  ? 304 VAL B CB  1 
ATOM   5794 C  CG1 . VAL B 1 304 ? 120.227 150.064 102.916 1.00 96.97  ? 304 VAL B CG1 1 
ATOM   5795 C  CG2 . VAL B 1 304 ? 118.356 149.145 101.547 1.00 96.97  ? 304 VAL B CG2 1 
ATOM   5796 N  N   . ASP B 1 305 ? 118.237 153.373 103.269 1.00 100.34 ? 305 ASP B N   1 
ATOM   5797 C  CA  . ASP B 1 305 ? 118.672 154.622 103.888 1.00 100.34 ? 305 ASP B CA  1 
ATOM   5798 C  C   . ASP B 1 305 ? 117.813 154.984 105.090 1.00 100.34 ? 305 ASP B C   1 
ATOM   5799 O  O   . ASP B 1 305 ? 118.253 155.725 105.973 1.00 100.34 ? 305 ASP B O   1 
ATOM   5800 C  CB  . ASP B 1 305 ? 118.647 155.756 102.866 1.00 100.34 ? 305 ASP B CB  1 
ATOM   5801 C  CG  . ASP B 1 305 ? 119.559 155.502 101.692 1.00 100.34 ? 305 ASP B CG  1 
ATOM   5802 O  OD1 . ASP B 1 305 ? 120.267 154.474 101.695 1.00 100.34 ? 305 ASP B OD1 1 
ATOM   5803 O  OD2 . ASP B 1 305 ? 119.570 156.329 100.759 1.00 100.34 ? 305 ASP B OD2 1 
ATOM   5804 N  N   . ASP B 1 306 ? 116.584 154.471 105.143 1.00 99.27  ? 306 ASP B N   1 
ATOM   5805 C  CA  . ASP B 1 306 ? 115.735 154.705 106.304 1.00 99.27  ? 306 ASP B CA  1 
ATOM   5806 C  C   . ASP B 1 306 ? 116.208 153.900 107.504 1.00 99.27  ? 306 ASP B C   1 
ATOM   5807 O  O   . ASP B 1 306 ? 116.034 154.321 108.651 1.00 99.27  ? 306 ASP B O   1 
ATOM   5808 C  CB  . ASP B 1 306 ? 114.288 154.370 105.965 1.00 99.27  ? 306 ASP B CB  1 
ATOM   5809 C  CG  . ASP B 1 306 ? 113.602 155.484 105.218 1.00 99.27  ? 306 ASP B CG  1 
ATOM   5810 O  OD1 . ASP B 1 306 ? 113.758 156.650 105.629 1.00 99.27  ? 306 ASP B OD1 1 
ATOM   5811 O  OD2 . ASP B 1 306 ? 112.905 155.202 104.223 1.00 99.27  ? 306 ASP B OD2 1 
ATOM   5812 N  N   . TYR B 1 307 ? 116.806 152.734 107.257 1.00 94.39  ? 307 TYR B N   1 
ATOM   5813 C  CA  . TYR B 1 307 ? 117.379 151.947 108.342 1.00 94.39  ? 307 TYR B CA  1 
ATOM   5814 C  C   . TYR B 1 307 ? 118.614 152.625 108.916 1.00 94.39  ? 307 TYR B C   1 
ATOM   5815 O  O   . TYR B 1 307 ? 118.825 152.624 110.131 1.00 94.39  ? 307 TYR B O   1 
ATOM   5816 C  CB  . TYR B 1 307 ? 117.728 150.547 107.850 1.00 94.39  ? 307 TYR B CB  1 
ATOM   5817 C  CG  . TYR B 1 307 ? 116.545 149.701 107.472 1.00 94.39  ? 307 TYR B CG  1 
ATOM   5818 C  CD1 . TYR B 1 307 ? 115.334 149.849 108.109 1.00 94.39  ? 307 TYR B CD1 1 
ATOM   5819 C  CD2 . TYR B 1 307 ? 116.647 148.743 106.480 1.00 94.39  ? 307 TYR B CD2 1 
ATOM   5820 C  CE1 . TYR B 1 307 ? 114.252 149.071 107.768 1.00 94.39  ? 307 TYR B CE1 1 
ATOM   5821 C  CE2 . TYR B 1 307 ? 115.571 147.963 106.132 1.00 94.39  ? 307 TYR B CE2 1 
ATOM   5822 C  CZ  . TYR B 1 307 ? 114.378 148.132 106.779 1.00 94.39  ? 307 TYR B CZ  1 
ATOM   5823 O  OH  . TYR B 1 307 ? 113.306 147.352 106.431 1.00 94.39  ? 307 TYR B OH  1 
ATOM   5824 N  N   . ILE B 1 308 ? 119.448 153.206 108.053 1.00 95.61  ? 308 ILE B N   1 
ATOM   5825 C  CA  . ILE B 1 308 ? 120.650 153.887 108.525 1.00 95.61  ? 308 ILE B CA  1 
ATOM   5826 C  C   . ILE B 1 308 ? 120.283 155.179 109.239 1.00 95.61  ? 308 ILE B C   1 
ATOM   5827 O  O   . ILE B 1 308 ? 120.948 155.588 110.198 1.00 95.61  ? 308 ILE B O   1 
ATOM   5828 C  CB  . ILE B 1 308 ? 121.612 154.144 107.353 1.00 95.61  ? 308 ILE B CB  1 
ATOM   5829 C  CG1 . ILE B 1 308 ? 121.721 152.906 106.472 1.00 95.61  ? 308 ILE B CG1 1 
ATOM   5830 C  CG2 . ILE B 1 308 ? 122.983 154.544 107.860 1.00 95.61  ? 308 ILE B CG2 1 
ATOM   5831 C  CD1 . ILE B 1 308 ? 122.421 151.764 107.123 1.00 95.61  ? 308 ILE B CD1 1 
ATOM   5832 N  N   . ALA B 1 309 ? 119.212 155.835 108.790 1.00 96.44  ? 309 ALA B N   1 
ATOM   5833 C  CA  . ALA B 1 309 ? 118.773 157.063 109.437 1.00 96.44  ? 309 ALA B CA  1 
ATOM   5834 C  C   . ALA B 1 309 ? 118.193 156.785 110.813 1.00 96.44  ? 309 ALA B C   1 
ATOM   5835 O  O   . ALA B 1 309 ? 118.257 157.638 111.702 1.00 96.44  ? 309 ALA B O   1 
ATOM   5836 C  CB  . ALA B 1 309 ? 117.749 157.778 108.563 1.00 96.44  ? 309 ALA B CB  1 
ATOM   5837 N  N   . LEU B 1 310 ? 117.625 155.594 111.006 1.00 95.14  ? 310 LEU B N   1 
ATOM   5838 C  CA  . LEU B 1 310 ? 117.062 155.242 112.304 1.00 95.14  ? 310 LEU B CA  1 
ATOM   5839 C  C   . LEU B 1 310 ? 118.157 155.002 113.332 1.00 95.14  ? 310 LEU B C   1 
ATOM   5840 O  O   . LEU B 1 310 ? 117.970 155.272 114.522 1.00 95.14  ? 310 LEU B O   1 
ATOM   5841 C  CB  . LEU B 1 310 ? 116.163 154.013 112.160 1.00 95.14  ? 310 LEU B CB  1 
ATOM   5842 C  CG  . LEU B 1 310 ? 115.285 153.530 113.317 1.00 95.14  ? 310 LEU B CG  1 
ATOM   5843 C  CD1 . LEU B 1 310 ? 114.000 152.991 112.758 1.00 95.14  ? 310 LEU B CD1 1 
ATOM   5844 C  CD2 . LEU B 1 310 ? 115.956 152.434 114.117 1.00 95.14  ? 310 LEU B CD2 1 
ATOM   5845 N  N   . ILE B 1 311 ? 119.307 154.495 112.889 1.00 95.09  ? 311 ILE B N   1 
ATOM   5846 C  CA  . ILE B 1 311 ? 120.397 154.206 113.813 1.00 95.09  ? 311 ILE B CA  1 
ATOM   5847 C  C   . ILE B 1 311 ? 121.038 155.498 114.294 1.00 95.09  ? 311 ILE B C   1 
ATOM   5848 O  O   . ILE B 1 311 ? 121.356 155.648 115.477 1.00 95.09  ? 311 ILE B O   1 
ATOM   5849 C  CB  . ILE B 1 311 ? 121.422 153.271 113.150 1.00 95.09  ? 311 ILE B CB  1 
ATOM   5850 C  CG1 . ILE B 1 311 ? 120.747 151.974 112.732 1.00 95.09  ? 311 ILE B CG1 1 
ATOM   5851 C  CG2 . ILE B 1 311 ? 122.557 152.952 114.094 1.00 95.09  ? 311 ILE B CG2 1 
ATOM   5852 C  CD1 . ILE B 1 311 ? 121.633 151.022 111.986 1.00 95.09  ? 311 ILE B CD1 1 
ATOM   5853 N  N   . ARG B 1 312 ? 121.212 156.463 113.392 1.00 99.41  ? 312 ARG B N   1 
ATOM   5854 C  CA  . ARG B 1 312 ? 121.852 157.714 113.781 1.00 99.41  ? 312 ARG B CA  1 
ATOM   5855 C  C   . ARG B 1 312 ? 120.913 158.590 114.598 1.00 99.41  ? 312 ARG B C   1 
ATOM   5856 O  O   . ARG B 1 312 ? 121.363 159.368 115.444 1.00 99.41  ? 312 ARG B O   1 
ATOM   5857 C  CB  . ARG B 1 312 ? 122.338 158.457 112.543 1.00 99.41  ? 312 ARG B CB  1 
ATOM   5858 C  CG  . ARG B 1 312 ? 123.581 157.856 111.937 1.00 99.41  ? 312 ARG B CG  1 
ATOM   5859 C  CD  . ARG B 1 312 ? 123.786 158.336 110.523 1.00 99.41  ? 312 ARG B CD  1 
ATOM   5860 N  NE  . ARG B 1 312 ? 124.767 157.519 109.822 1.00 99.41  ? 312 ARG B NE  1 
ATOM   5861 C  CZ  . ARG B 1 312 ? 124.893 157.478 108.501 1.00 99.41  ? 312 ARG B CZ  1 
ATOM   5862 N  NH1 . ARG B 1 312 ? 124.095 158.209 107.735 1.00 99.41  ? 312 ARG B NH1 1 
ATOM   5863 N  NH2 . ARG B 1 312 ? 125.811 156.701 107.945 1.00 99.41  ? 312 ARG B NH2 1 
ATOM   5864 N  N   . ARG B 1 313 ? 119.608 158.476 114.361 1.00 98.83  ? 313 ARG B N   1 
ATOM   5865 C  CA  . ARG B 1 313 ? 118.649 159.270 115.119 1.00 98.83  ? 313 ARG B CA  1 
ATOM   5866 C  C   . ARG B 1 313 ? 118.510 158.746 116.540 1.00 98.83  ? 313 ARG B C   1 
ATOM   5867 O  O   . ARG B 1 313 ? 118.517 159.521 117.503 1.00 98.83  ? 313 ARG B O   1 
ATOM   5868 C  CB  . ARG B 1 313 ? 117.301 159.274 114.403 1.00 98.83  ? 313 ARG B CB  1 
ATOM   5869 C  CG  . ARG B 1 313 ? 116.133 159.706 115.256 1.00 98.83  ? 313 ARG B CG  1 
ATOM   5870 C  CD  . ARG B 1 313 ? 114.848 159.719 114.457 1.00 98.83  ? 313 ARG B CD  1 
ATOM   5871 N  NE  . ARG B 1 313 ? 114.343 158.376 114.194 1.00 98.83  ? 313 ARG B NE  1 
ATOM   5872 C  CZ  . ARG B 1 313 ? 114.226 157.848 112.982 1.00 98.83  ? 313 ARG B CZ  1 
ATOM   5873 N  NH1 . ARG B 1 313 ? 114.581 158.547 111.916 1.00 98.83  ? 313 ARG B NH1 1 
ATOM   5874 N  NH2 . ARG B 1 313 ? 113.752 156.621 112.833 1.00 98.83  ? 313 ARG B NH2 1 
ATOM   5875 N  N   . THR B 1 314 ? 118.402 157.428 116.694 1.00 99.15  ? 314 THR B N   1 
ATOM   5876 C  CA  . THR B 1 314 ? 118.246 156.839 118.016 1.00 99.15  ? 314 THR B CA  1 
ATOM   5877 C  C   . THR B 1 314 ? 119.574 156.648 118.734 1.00 99.15  ? 314 THR B C   1 
ATOM   5878 O  O   . THR B 1 314 ? 119.612 156.703 119.967 1.00 99.15  ? 314 THR B O   1 
ATOM   5879 C  CB  . THR B 1 314 ? 117.519 155.500 117.912 1.00 99.15  ? 314 THR B CB  1 
ATOM   5880 O  OG1 . THR B 1 314 ? 118.096 154.727 116.857 1.00 99.15  ? 314 THR B OG1 1 
ATOM   5881 C  CG2 . THR B 1 314 ? 116.057 155.721 117.607 1.00 99.15  ? 314 THR B CG2 1 
ATOM   5882 N  N   . GLY B 1 315 ? 120.658 156.438 117.997 1.00 99.02  ? 315 GLY B N   1 
ATOM   5883 C  CA  . GLY B 1 315 ? 121.952 156.224 118.626 1.00 99.02  ? 315 GLY B CA  1 
ATOM   5884 C  C   . GLY B 1 315 ? 122.085 154.872 119.287 1.00 99.02  ? 315 GLY B C   1 
ATOM   5885 O  O   . GLY B 1 315 ? 122.794 154.740 120.292 1.00 99.02  ? 315 GLY B O   1 
ATOM   5886 N  N   . THR B 1 316 ? 121.426 153.859 118.742 1.00 95.90  ? 316 THR B N   1 
ATOM   5887 C  CA  . THR B 1 316 ? 121.379 152.553 119.373 1.00 95.90  ? 316 THR B CA  1 
ATOM   5888 C  C   . THR B 1 316 ? 122.449 151.628 118.813 1.00 95.90  ? 316 THR B C   1 
ATOM   5889 O  O   . THR B 1 316 ? 122.911 151.784 117.681 1.00 95.90  ? 316 THR B O   1 
ATOM   5890 C  CB  . THR B 1 316 ? 120.000 151.917 119.204 1.00 95.90  ? 316 THR B CB  1 
ATOM   5891 O  OG1 . THR B 1 316 ? 119.992 150.631 119.830 1.00 95.90  ? 316 THR B OG1 1 
ATOM   5892 C  CG2 . THR B 1 316 ? 119.640 151.778 117.745 1.00 95.90  ? 316 THR B CG2 1 
ATOM   5893 N  N   . LYS B 1 317 ? 122.862 150.676 119.644 1.00 92.96  ? 317 LYS B N   1 
ATOM   5894 C  CA  . LYS B 1 317 ? 123.774 149.614 119.250 1.00 92.96  ? 317 LYS B CA  1 
ATOM   5895 C  C   . LYS B 1 317 ? 123.046 148.312 118.982 1.00 92.96  ? 317 LYS B C   1 
ATOM   5896 O  O   . LYS B 1 317 ? 123.690 147.302 118.698 1.00 92.96  ? 317 LYS B O   1 
ATOM   5897 C  CB  . LYS B 1 317 ? 124.831 149.392 120.330 1.00 92.96  ? 317 LYS B CB  1 
ATOM   5898 C  CG  . LYS B 1 317 ? 125.498 150.655 120.800 1.00 92.96  ? 317 LYS B CG  1 
ATOM   5899 C  CD  . LYS B 1 317 ? 126.420 151.204 119.738 1.00 92.96  ? 317 LYS B CD  1 
ATOM   5900 C  CE  . LYS B 1 317 ? 126.897 152.592 120.108 1.00 92.96  ? 317 LYS B CE  1 
ATOM   5901 N  NZ  . LYS B 1 317 ? 127.247 152.670 121.551 1.00 92.96  ? 317 LYS B NZ  1 
ATOM   5902 N  N   . HIS B 1 318 ? 121.724 148.311 119.071 1.00 88.69  ? 318 HIS B N   1 
ATOM   5903 C  CA  . HIS B 1 318 ? 120.947 147.096 118.930 1.00 88.69  ? 318 HIS B CA  1 
ATOM   5904 C  C   . HIS B 1 318 ? 120.062 147.110 117.700 1.00 88.69  ? 318 HIS B C   1 
ATOM   5905 O  O   . HIS B 1 318 ? 119.140 146.300 117.604 1.00 88.69  ? 318 HIS B O   1 
ATOM   5906 C  CB  . HIS B 1 318 ? 120.123 146.864 120.190 1.00 88.69  ? 318 HIS B CB  1 
ATOM   5907 C  CG  . HIS B 1 318 ? 120.953 146.469 121.368 1.00 88.69  ? 318 HIS B CG  1 
ATOM   5908 N  ND1 . HIS B 1 318 ? 121.700 147.375 122.086 1.00 88.69  ? 318 HIS B ND1 1 
ATOM   5909 C  CD2 . HIS B 1 318 ? 121.187 145.261 121.928 1.00 88.69  ? 318 HIS B CD2 1 
ATOM   5910 C  CE1 . HIS B 1 318 ? 122.340 146.746 123.053 1.00 88.69  ? 318 HIS B CE1 1 
ATOM   5911 N  NE2 . HIS B 1 318 ? 122.048 145.462 122.977 1.00 88.69  ? 318 HIS B NE2 1 
ATOM   5912 N  N   . PHE B 1 319 ? 120.319 148.011 116.762 1.00 86.10  ? 319 PHE B N   1 
ATOM   5913 C  CA  . PHE B 1 319 ? 119.734 147.956 115.435 1.00 86.10  ? 319 PHE B CA  1 
ATOM   5914 C  C   . PHE B 1 319 ? 120.856 147.784 114.426 1.00 86.10  ? 319 PHE B C   1 
ATOM   5915 O  O   . PHE B 1 319 ? 121.905 148.420 114.540 1.00 86.10  ? 319 PHE B O   1 
ATOM   5916 C  CB  . PHE B 1 319 ? 118.930 149.209 115.124 1.00 86.10  ? 319 PHE B CB  1 
ATOM   5917 C  CG  . PHE B 1 319 ? 117.927 149.028 114.030 1.00 86.10  ? 319 PHE B CG  1 
ATOM   5918 C  CD1 . PHE B 1 319 ? 118.117 149.618 112.801 1.00 86.10  ? 319 PHE B CD1 1 
ATOM   5919 C  CD2 . PHE B 1 319 ? 116.791 148.274 114.232 1.00 86.10  ? 319 PHE B CD2 1 
ATOM   5920 C  CE1 . PHE B 1 319 ? 117.200 149.463 111.797 1.00 86.10  ? 319 PHE B CE1 1 
ATOM   5921 C  CE2 . PHE B 1 319 ? 115.870 148.114 113.224 1.00 86.10  ? 319 PHE B CE2 1 
ATOM   5922 C  CZ  . PHE B 1 319 ? 116.075 148.719 112.011 1.00 86.10  ? 319 PHE B CZ  1 
ATOM   5923 N  N   . GLY B 1 320 ? 120.643 146.909 113.453 1.00 84.42  ? 320 GLY B N   1 
ATOM   5924 C  CA  . GLY B 1 320 ? 121.657 146.647 112.457 1.00 84.42  ? 320 GLY B CA  1 
ATOM   5925 C  C   . GLY B 1 320 ? 121.030 146.245 111.146 1.00 84.42  ? 320 GLY B C   1 
ATOM   5926 O  O   . GLY B 1 320 ? 119.813 146.301 110.981 1.00 84.42  ? 320 GLY B O   1 
ATOM   5927 N  N   . LEU B 1 321 ? 121.863 145.834 110.204 1.00 83.54  ? 321 LEU B N   1 
ATOM   5928 C  CA  . LEU B 1 321 ? 121.402 145.421 108.890 1.00 83.54  ? 321 LEU B CA  1 
ATOM   5929 C  C   . LEU B 1 321 ? 121.724 143.956 108.663 1.00 83.54  ? 321 LEU B C   1 
ATOM   5930 O  O   . LEU B 1 321 ? 122.767 143.465 109.094 1.00 83.54  ? 321 LEU B O   1 
ATOM   5931 C  CB  . LEU B 1 321 ? 122.049 146.249 107.786 1.00 83.54  ? 321 LEU B CB  1 
ATOM   5932 C  CG  . LEU B 1 321 ? 121.528 147.656 107.539 1.00 83.54  ? 321 LEU B CG  1 
ATOM   5933 C  CD1 . LEU B 1 321 ? 122.102 148.153 106.244 1.00 83.54  ? 321 LEU B CD1 1 
ATOM   5934 C  CD2 . LEU B 1 321 ? 120.026 147.659 107.488 1.00 83.54  ? 321 LEU B CD2 1 
ATOM   5935 N  N   . LEU B 1 322 ? 120.823 143.269 107.981 1.00 79.73  ? 322 LEU B N   1 
ATOM   5936 C  CA  . LEU B 1 322 ? 121.058 141.916 107.519 1.00 79.73  ? 322 LEU B CA  1 
ATOM   5937 C  C   . LEU B 1 322 ? 121.171 141.954 106.005 1.00 79.73  ? 322 LEU B C   1 
ATOM   5938 O  O   . LEU B 1 322 ? 120.320 142.537 105.332 1.00 79.73  ? 322 LEU B O   1 
ATOM   5939 C  CB  . LEU B 1 322 ? 119.928 140.991 107.960 1.00 79.73  ? 322 LEU B CB  1 
ATOM   5940 C  CG  . LEU B 1 322 ? 120.163 139.489 107.950 1.00 79.73  ? 322 LEU B CG  1 
ATOM   5941 C  CD1 . LEU B 1 322 ? 119.474 138.877 109.128 1.00 79.73  ? 322 LEU B CD1 1 
ATOM   5942 C  CD2 . LEU B 1 322 ? 119.612 138.901 106.695 1.00 79.73  ? 322 LEU B CD2 1 
ATOM   5943 N  N   . LEU B 1 323 ? 122.218 141.345 105.476 1.00 82.09  ? 323 LEU B N   1 
ATOM   5944 C  CA  . LEU B 1 323 ? 122.489 141.376 104.050 1.00 82.09  ? 323 LEU B CA  1 
ATOM   5945 C  C   . LEU B 1 323 ? 122.195 140.017 103.438 1.00 82.09  ? 323 LEU B C   1 
ATOM   5946 O  O   . LEU B 1 323 ? 122.774 139.008 103.835 1.00 82.09  ? 323 LEU B O   1 
ATOM   5947 C  CB  . LEU B 1 323 ? 123.940 141.765 103.794 1.00 82.09  ? 323 LEU B CB  1 
ATOM   5948 C  CG  . LEU B 1 323 ? 124.227 142.501 102.498 1.00 82.09  ? 323 LEU B CG  1 
ATOM   5949 C  CD1 . LEU B 1 323 ? 123.524 143.828 102.519 1.00 82.09  ? 323 LEU B CD1 1 
ATOM   5950 C  CD2 . LEU B 1 323 ? 125.711 142.693 102.346 1.00 82.09  ? 323 LEU B CD2 1 
ATOM   5951 N  N   . ASP B 1 324 ? 121.296 139.994 102.471 1.00 86.23  ? 324 ASP B N   1 
ATOM   5952 C  CA  . ASP B 1 324 ? 121.000 138.783 101.728 1.00 86.23  ? 324 ASP B CA  1 
ATOM   5953 C  C   . ASP B 1 324 ? 121.752 138.843 100.409 1.00 86.23  ? 324 ASP B C   1 
ATOM   5954 O  O   . ASP B 1 324 ? 121.606 139.803 99.653  1.00 86.23  ? 324 ASP B O   1 
ATOM   5955 C  CB  . ASP B 1 324 ? 119.494 138.654 101.496 1.00 86.23  ? 324 ASP B CB  1 
ATOM   5956 C  CG  . ASP B 1 324 ? 119.076 137.265 101.079 1.00 86.23  ? 324 ASP B CG  1 
ATOM   5957 O  OD1 . ASP B 1 324 ? 118.556 136.513 101.925 1.00 86.23  ? 324 ASP B OD1 1 
ATOM   5958 O  OD2 . ASP B 1 324 ? 119.239 136.932 99.894  1.00 86.23  ? 324 ASP B OD2 1 
ATOM   5959 N  N   . THR B 1 325 ? 122.553 137.816 100.128 1.00 86.02  ? 325 THR B N   1 
ATOM   5960 C  CA  . THR B 1 325 ? 123.410 137.827 98.947  1.00 86.02  ? 325 THR B CA  1 
ATOM   5961 C  C   . THR B 1 325 ? 122.678 137.507 97.653  1.00 86.02  ? 325 THR B C   1 
ATOM   5962 O  O   . THR B 1 325 ? 123.335 137.320 96.628  1.00 86.02  ? 325 THR B O   1 
ATOM   5963 C  CB  . THR B 1 325 ? 124.571 136.847 99.106  1.00 86.02  ? 325 THR B CB  1 
ATOM   5964 O  OG1 . THR B 1 325 ? 124.087 135.505 98.991  1.00 86.02  ? 325 THR B OG1 1 
ATOM   5965 C  CG2 . THR B 1 325 ? 125.247 137.028 100.429 1.00 86.02  ? 325 THR B CG2 1 
ATOM   5966 N  N   . GLY B 1 326 ? 121.347 137.444 97.663  1.00 87.66  ? 326 GLY B N   1 
ATOM   5967 C  CA  . GLY B 1 326 ? 120.612 137.338 96.419  1.00 87.66  ? 326 GLY B CA  1 
ATOM   5968 C  C   . GLY B 1 326 ? 120.602 138.622 95.623  1.00 87.66  ? 326 GLY B C   1 
ATOM   5969 O  O   . GLY B 1 326 ? 120.238 138.617 94.445  1.00 87.66  ? 326 GLY B O   1 
ATOM   5970 N  N   . ILE B 1 327 ? 120.997 139.734 96.244  1.00 88.69  ? 327 ILE B N   1 
ATOM   5971 C  CA  . ILE B 1 327 ? 121.084 140.994 95.529  1.00 88.69  ? 327 ILE B CA  1 
ATOM   5972 C  C   . ILE B 1 327 ? 122.293 141.043 94.605  1.00 88.69  ? 327 ILE B C   1 
ATOM   5973 O  O   . ILE B 1 327 ? 122.321 141.853 93.677  1.00 88.69  ? 327 ILE B O   1 
ATOM   5974 C  CB  . ILE B 1 327 ? 121.095 142.161 96.530  1.00 88.69  ? 327 ILE B CB  1 
ATOM   5975 C  CG1 . ILE B 1 327 ? 122.358 142.137 97.380  1.00 88.69  ? 327 ILE B CG1 1 
ATOM   5976 C  CG2 . ILE B 1 327 ? 119.892 142.081 97.427  1.00 88.69  ? 327 ILE B CG2 1 
ATOM   5977 C  CD1 . ILE B 1 327 ? 122.450 143.266 98.363  1.00 88.69  ? 327 ILE B CD1 1 
ATOM   5978 N  N   . PHE B 1 328 ? 123.284 140.185 94.814  1.00 89.25  ? 328 PHE B N   1 
ATOM   5979 C  CA  . PHE B 1 328 ? 124.467 140.149 93.971  1.00 89.25  ? 328 PHE B CA  1 
ATOM   5980 C  C   . PHE B 1 328 ? 124.328 139.198 92.799  1.00 89.25  ? 328 PHE B C   1 
ATOM   5981 O  O   . PHE B 1 328 ? 125.289 139.031 92.049  1.00 89.25  ? 328 PHE B O   1 
ATOM   5982 C  CB  . PHE B 1 328 ? 125.688 139.754 94.793  1.00 89.25  ? 328 PHE B CB  1 
ATOM   5983 C  CG  . PHE B 1 328 ? 125.928 140.633 95.967  1.00 89.25  ? 328 PHE B CG  1 
ATOM   5984 C  CD1 . PHE B 1 328 ? 126.165 141.980 95.797  1.00 89.25  ? 328 PHE B CD1 1 
ATOM   5985 C  CD2 . PHE B 1 328 ? 125.913 140.117 97.240  1.00 89.25  ? 328 PHE B CD2 1 
ATOM   5986 C  CE1 . PHE B 1 328 ? 126.384 142.795 96.875  1.00 89.25  ? 328 PHE B CE1 1 
ATOM   5987 C  CE2 . PHE B 1 328 ? 126.134 140.928 98.323  1.00 89.25  ? 328 PHE B CE2 1 
ATOM   5988 C  CZ  . PHE B 1 328 ? 126.369 142.268 98.137  1.00 89.25  ? 328 PHE B CZ  1 
ATOM   5989 N  N   . GLN B 1 329 ? 123.161 138.583 92.629  1.00 94.34  ? 329 GLN B N   1 
ATOM   5990 C  CA  . GLN B 1 329 ? 122.951 137.591 91.584  1.00 94.34  ? 329 GLN B CA  1 
ATOM   5991 C  C   . GLN B 1 329 ? 123.028 138.225 90.200  1.00 94.34  ? 329 GLN B C   1 
ATOM   5992 O  O   . GLN B 1 329 ? 122.388 139.242 89.930  1.00 94.34  ? 329 GLN B O   1 
ATOM   5993 C  CB  . GLN B 1 329 ? 121.597 136.921 91.785  1.00 94.34  ? 329 GLN B CB  1 
ATOM   5994 C  CG  . GLN B 1 329 ? 121.188 136.003 90.673  1.00 94.34  ? 329 GLN B CG  1 
ATOM   5995 C  CD  . GLN B 1 329 ? 119.704 135.787 90.630  1.00 94.34  ? 329 GLN B CD  1 
ATOM   5996 O  OE1 . GLN B 1 329 ? 118.988 136.175 91.545  1.00 94.34  ? 329 GLN B OE1 1 
ATOM   5997 N  NE2 . GLN B 1 329 ? 119.227 135.166 89.566  1.00 94.34  ? 329 GLN B NE2 1 
ATOM   5998 N  N   . ASP B 1 330 ? 123.831 137.623 89.326  1.00 94.84  ? 330 ASP B N   1 
ATOM   5999 C  CA  . ASP B 1 330 ? 124.111 138.188 88.016  1.00 94.84  ? 330 ASP B CA  1 
ATOM   6000 C  C   . ASP B 1 330 ? 123.604 137.329 86.869  1.00 94.84  ? 330 ASP B C   1 
ATOM   6001 O  O   . ASP B 1 330 ? 123.478 137.829 85.748  1.00 94.84  ? 330 ASP B O   1 
ATOM   6002 C  CB  . ASP B 1 330 ? 125.617 138.433 87.859  1.00 94.84  ? 330 ASP B CB  1 
ATOM   6003 C  CG  . ASP B 1 330 ? 126.430 137.166 87.924  1.00 94.84  ? 330 ASP B CG  1 
ATOM   6004 O  OD1 . ASP B 1 330 ? 125.956 136.172 88.503  1.00 94.84  ? 330 ASP B OD1 1 
ATOM   6005 O  OD2 . ASP B 1 330 ? 127.559 137.165 87.398  1.00 94.84  ? 330 ASP B OD2 1 
ATOM   6006 N  N   . ARG B 1 331 ? 123.320 136.058 87.109  1.00 94.46  ? 331 ARG B N   1 
ATOM   6007 C  CA  . ARG B 1 331 ? 122.787 135.189 86.078  1.00 94.46  ? 331 ARG B CA  1 
ATOM   6008 C  C   . ARG B 1 331 ? 121.392 134.731 86.482  1.00 94.46  ? 331 ARG B C   1 
ATOM   6009 O  O   . ARG B 1 331 ? 121.110 134.596 87.674  1.00 94.46  ? 331 ARG B O   1 
ATOM   6010 C  CB  . ARG B 1 331 ? 123.713 133.991 85.866  1.00 94.46  ? 331 ARG B CB  1 
ATOM   6011 C  CG  . ARG B 1 331 ? 125.028 134.374 85.228  1.00 94.46  ? 331 ARG B CG  1 
ATOM   6012 C  CD  . ARG B 1 331 ? 125.984 133.202 85.138  1.00 94.46  ? 331 ARG B CD  1 
ATOM   6013 N  NE  . ARG B 1 331 ? 126.183 132.540 86.422  1.00 94.46  ? 331 ARG B NE  1 
ATOM   6014 C  CZ  . ARG B 1 331 ? 127.003 132.969 87.374  1.00 94.46  ? 331 ARG B CZ  1 
ATOM   6015 N  NH1 . ARG B 1 331 ? 127.715 134.071 87.202  1.00 94.46  ? 331 ARG B NH1 1 
ATOM   6016 N  NH2 . ARG B 1 331 ? 127.114 132.293 88.503  1.00 94.46  ? 331 ARG B NH2 1 
ATOM   6017 N  N   . PRO B 1 332 ? 120.491 134.511 85.524  1.00 99.88  ? 332 PRO B N   1 
ATOM   6018 C  CA  . PRO B 1 332 ? 119.087 134.289 85.880  1.00 99.88  ? 332 PRO B CA  1 
ATOM   6019 C  C   . PRO B 1 332 ? 118.826 132.923 86.493  1.00 99.88  ? 332 PRO B C   1 
ATOM   6020 O  O   . PRO B 1 332 ? 119.461 131.923 86.160  1.00 99.88  ? 332 PRO B O   1 
ATOM   6021 C  CB  . PRO B 1 332 ? 118.363 134.432 84.540  1.00 99.88  ? 332 PRO B CB  1 
ATOM   6022 C  CG  . PRO B 1 332 ? 119.377 134.082 83.546  1.00 99.88  ? 332 PRO B CG  1 
ATOM   6023 C  CD  . PRO B 1 332 ? 120.651 134.642 84.067  1.00 99.88  ? 332 PRO B CD  1 
ATOM   6024 N  N   . ILE B 1 333 ? 117.876 132.911 87.414  1.00 104.29 ? 333 ILE B N   1 
ATOM   6025 C  CA  . ILE B 1 333 ? 117.301 131.670 87.934  1.00 104.29 ? 333 ILE B CA  1 
ATOM   6026 C  C   . ILE B 1 333 ? 116.537 130.988 86.807  1.00 104.29 ? 333 ILE B C   1 
ATOM   6027 O  O   . ILE B 1 333 ? 115.765 131.660 86.108  1.00 104.29 ? 333 ILE B O   1 
ATOM   6028 C  CB  . ILE B 1 333 ? 116.389 131.978 89.118  1.00 104.29 ? 333 ILE B CB  1 
ATOM   6029 C  CG1 . ILE B 1 333 ? 117.218 132.468 90.302  1.00 104.29 ? 333 ILE B CG1 1 
ATOM   6030 C  CG2 . ILE B 1 333 ? 115.561 130.778 89.524  1.00 104.29 ? 333 ILE B CG2 1 
ATOM   6031 C  CD1 . ILE B 1 333 ? 116.418 133.208 91.337  1.00 104.29 ? 333 ILE B CD1 1 
ATOM   6032 N  N   . PRO B 1 334 ? 116.744 129.689 86.572  1.00 114.03 ? 334 PRO B N   1 
ATOM   6033 C  CA  . PRO B 1 334 ? 116.168 129.045 85.385  1.00 114.03 ? 334 PRO B CA  1 
ATOM   6034 C  C   . PRO B 1 334 ? 114.653 128.964 85.448  1.00 114.03 ? 334 PRO B C   1 
ATOM   6035 O  O   . PRO B 1 334 ? 114.055 129.001 86.524  1.00 114.03 ? 334 PRO B O   1 
ATOM   6036 C  CB  . PRO B 1 334 ? 116.798 127.649 85.399  1.00 114.03 ? 334 PRO B CB  1 
ATOM   6037 C  CG  . PRO B 1 334 ? 117.997 127.779 86.244  1.00 114.03 ? 334 PRO B CG  1 
ATOM   6038 C  CD  . PRO B 1 334 ? 117.651 128.780 87.287  1.00 114.03 ? 334 PRO B CD  1 
ATOM   6039 N  N   . LEU B 1 335 ? 114.040 128.875 84.274  1.00 128.05 ? 335 LEU B N   1 
ATOM   6040 C  CA  . LEU B 1 335 ? 112.590 128.868 84.184  1.00 128.05 ? 335 LEU B CA  1 
ATOM   6041 C  C   . LEU B 1 335 ? 112.024 127.561 84.712  1.00 128.05 ? 335 LEU B C   1 
ATOM   6042 O  O   . LEU B 1 335 ? 112.519 126.476 84.398  1.00 128.05 ? 335 LEU B O   1 
ATOM   6043 C  CB  . LEU B 1 335 ? 112.146 129.081 82.741  1.00 128.05 ? 335 LEU B CB  1 
ATOM   6044 C  CG  . LEU B 1 335 ? 112.249 130.516 82.237  1.00 128.05 ? 335 LEU B CG  1 
ATOM   6045 C  CD1 . LEU B 1 335 ? 112.274 130.543 80.721  1.00 128.05 ? 335 LEU B CD1 1 
ATOM   6046 C  CD2 . LEU B 1 335 ? 111.099 131.340 82.773  1.00 128.05 ? 335 LEU B CD2 1 
ATOM   6047 N  N   . LYS B 1 336 ? 110.997 127.684 85.542  1.00 136.15 ? 336 LYS B N   1 
ATOM   6048 C  CA  . LYS B 1 336 ? 110.251 126.536 86.014  1.00 136.15 ? 336 LYS B CA  1 
ATOM   6049 C  C   . LYS B 1 336 ? 109.566 125.857 84.830  1.00 136.15 ? 336 LYS B C   1 
ATOM   6050 O  O   . LYS B 1 336 ? 109.165 126.534 83.878  1.00 136.15 ? 336 LYS B O   1 
ATOM   6051 C  CB  . LYS B 1 336 ? 109.234 126.995 87.059  1.00 136.15 ? 336 LYS B CB  1 
ATOM   6052 C  CG  . LYS B 1 336 ? 108.408 125.917 87.716  1.00 136.15 ? 336 LYS B CG  1 
ATOM   6053 C  CD  . LYS B 1 336 ? 107.633 126.494 88.879  1.00 136.15 ? 336 LYS B CD  1 
ATOM   6054 C  CE  . LYS B 1 336 ? 106.518 127.406 88.404  1.00 136.15 ? 336 LYS B CE  1 
ATOM   6055 N  NZ  . LYS B 1 336 ? 105.689 127.891 89.540  1.00 136.15 ? 336 LYS B NZ  1 
ATOM   6056 N  N   . PRO B 1 337 ? 109.492 124.524 84.817  1.00 139.86 ? 337 PRO B N   1 
ATOM   6057 C  CA  . PRO B 1 337 ? 108.809 123.839 83.711  1.00 139.86 ? 337 PRO B CA  1 
ATOM   6058 C  C   . PRO B 1 337 ? 107.323 124.163 83.677  1.00 139.86 ? 337 PRO B C   1 
ATOM   6059 O  O   . PRO B 1 337 ? 106.603 123.985 84.662  1.00 139.86 ? 337 PRO B O   1 
ATOM   6060 C  CB  . PRO B 1 337 ? 109.058 122.353 84.005  1.00 139.86 ? 337 PRO B CB  1 
ATOM   6061 C  CG  . PRO B 1 337 ? 109.503 122.302 85.437  1.00 139.86 ? 337 PRO B CG  1 
ATOM   6062 C  CD  . PRO B 1 337 ? 110.251 123.573 85.646  1.00 139.86 ? 337 PRO B CD  1 
ATOM   6063 N  N   . GLY B 1 338 ? 106.874 124.660 82.525  1.00 140.23 ? 338 GLY B N   1 
ATOM   6064 C  CA  . GLY B 1 338 ? 105.494 125.044 82.341  1.00 140.23 ? 338 GLY B CA  1 
ATOM   6065 C  C   . GLY B 1 338 ? 105.244 126.525 82.151  1.00 140.23 ? 338 GLY B C   1 
ATOM   6066 O  O   . GLY B 1 338 ? 104.121 126.902 81.793  1.00 140.23 ? 338 GLY B O   1 
ATOM   6067 N  N   . GLU B 1 339 ? 106.238 127.379 82.378  1.00 137.38 ? 339 GLU B N   1 
ATOM   6068 C  CA  . GLU B 1 339 ? 106.072 128.811 82.180  1.00 137.38 ? 339 GLU B CA  1 
ATOM   6069 C  C   . GLU B 1 339 ? 106.898 129.279 80.985  1.00 137.38 ? 339 GLU B C   1 
ATOM   6070 O  O   . GLU B 1 339 ? 107.955 128.719 80.676  1.00 137.38 ? 339 GLU B O   1 
ATOM   6071 C  CB  . GLU B 1 339 ? 106.453 129.590 83.445  1.00 137.38 ? 339 GLU B CB  1 
ATOM   6072 C  CG  . GLU B 1 339 ? 107.926 129.545 83.821  1.00 137.38 ? 339 GLU B CG  1 
ATOM   6073 C  CD  . GLU B 1 339 ? 108.228 130.244 85.132  1.00 137.38 ? 339 GLU B CD  1 
ATOM   6074 O  OE1 . GLU B 1 339 ? 107.285 130.762 85.765  1.00 137.38 ? 339 GLU B OE1 1 
ATOM   6075 O  OE2 . GLU B 1 339 ? 109.412 130.268 85.532  1.00 137.38 ? 339 GLU B OE2 1 
ATOM   6076 N  N   . LEU B 1 340 ? 106.377 130.288 80.291  1.00 138.19 ? 340 LEU B N   1 
ATOM   6077 C  CA  . LEU B 1 340 ? 107.080 131.014 79.252  1.00 138.19 ? 340 LEU B CA  1 
ATOM   6078 C  C   . LEU B 1 340 ? 107.559 132.346 79.824  1.00 138.19 ? 340 LEU B C   1 
ATOM   6079 O  O   . LEU B 1 340 ? 107.064 132.769 80.872  1.00 138.19 ? 340 LEU B O   1 
ATOM   6080 C  CB  . LEU B 1 340 ? 106.166 131.219 78.032  1.00 138.19 ? 340 LEU B CB  1 
ATOM   6081 C  CG  . LEU B 1 340 ? 104.979 132.182 78.028  1.00 138.19 ? 340 LEU B CG  1 
ATOM   6082 C  CD1 . LEU B 1 340 ? 104.667 132.586 76.602  1.00 138.19 ? 340 LEU B CD1 1 
ATOM   6083 C  CD2 . LEU B 1 340 ? 103.745 131.545 78.637  1.00 138.19 ? 340 LEU B CD2 1 
ATOM   6084 N  N   . PRO B 1 341 ? 108.561 132.994 79.211  1.00 138.53 ? 341 PRO B N   1 
ATOM   6085 C  CA  . PRO B 1 341 ? 109.070 134.251 79.789  1.00 138.53 ? 341 PRO B CA  1 
ATOM   6086 C  C   . PRO B 1 341 ? 108.063 135.391 79.768  1.00 138.53 ? 341 PRO B C   1 
ATOM   6087 O  O   . PRO B 1 341 ? 107.473 135.698 78.728  1.00 138.53 ? 341 PRO B O   1 
ATOM   6088 C  CB  . PRO B 1 341 ? 110.289 134.569 78.914  1.00 138.53 ? 341 PRO B CB  1 
ATOM   6089 C  CG  . PRO B 1 341 ? 110.752 133.258 78.438  1.00 138.53 ? 341 PRO B CG  1 
ATOM   6090 C  CD  . PRO B 1 341 ? 109.510 132.448 78.220  1.00 138.53 ? 341 PRO B CD  1 
ATOM   6091 N  N   . GLY B 1 342 ? 107.870 136.029 80.924  1.00 135.09 ? 342 GLY B N   1 
ATOM   6092 C  CA  . GLY B 1 342 ? 107.025 137.204 80.989  1.00 135.09 ? 342 GLY B CA  1 
ATOM   6093 C  C   . GLY B 1 342 ? 106.105 137.261 82.192  1.00 135.09 ? 342 GLY B C   1 
ATOM   6094 O  O   . GLY B 1 342 ? 105.815 138.353 82.689  1.00 135.09 ? 342 GLY B O   1 
ATOM   6095 N  N   . GLN B 1 343 ? 105.635 136.113 82.686  1.00 132.86 ? 343 GLN B N   1 
ATOM   6096 C  CA  . GLN B 1 343 ? 104.673 136.153 83.784  1.00 132.86 ? 343 GLN B CA  1 
ATOM   6097 C  C   . GLN B 1 343 ? 105.367 136.064 85.137  1.00 132.86 ? 343 GLN B C   1 
ATOM   6098 O  O   . GLN B 1 343 ? 104.752 136.324 86.177  1.00 132.86 ? 343 GLN B O   1 
ATOM   6099 C  CB  . GLN B 1 343 ? 103.646 135.033 83.646  1.00 132.86 ? 343 GLN B CB  1 
ATOM   6100 C  CG  . GLN B 1 343 ? 104.241 133.658 83.532  1.00 132.86 ? 343 GLN B CG  1 
ATOM   6101 C  CD  . GLN B 1 343 ? 104.263 133.166 82.110  1.00 132.86 ? 343 GLN B CD  1 
ATOM   6102 O  OE1 . GLN B 1 343 ? 104.181 133.950 81.166  1.00 132.86 ? 343 GLN B OE1 1 
ATOM   6103 N  NE2 . GLN B 1 343 ? 104.368 131.856 81.945  1.00 132.86 ? 343 GLN B NE2 1 
ATOM   6104 N  N   . ARG B 1 344 ? 106.637 135.688 85.147  1.00 121.05 ? 344 ARG B N   1 
ATOM   6105 C  CA  . ARG B 1 344 ? 107.392 135.760 86.385  1.00 121.05 ? 344 ARG B CA  1 
ATOM   6106 C  C   . ARG B 1 344 ? 108.012 137.149 86.519  1.00 121.05 ? 344 ARG B C   1 
ATOM   6107 O  O   . ARG B 1 344 ? 108.233 137.831 85.511  1.00 121.05 ? 344 ARG B O   1 
ATOM   6108 C  CB  . ARG B 1 344 ? 108.459 134.662 86.424  1.00 121.05 ? 344 ARG B CB  1 
ATOM   6109 C  CG  . ARG B 1 344 ? 109.792 135.011 85.808  1.00 121.05 ? 344 ARG B CG  1 
ATOM   6110 C  CD  . ARG B 1 344 ? 110.784 133.894 86.042  1.00 121.05 ? 344 ARG B CD  1 
ATOM   6111 N  NE  . ARG B 1 344 ? 112.112 134.228 85.551  1.00 121.05 ? 344 ARG B NE  1 
ATOM   6112 C  CZ  . ARG B 1 344 ? 113.198 133.519 85.825  1.00 121.05 ? 344 ARG B CZ  1 
ATOM   6113 N  NH1 . ARG B 1 344 ? 113.105 132.443 86.588  1.00 121.05 ? 344 ARG B NH1 1 
ATOM   6114 N  NH2 . ARG B 1 344 ? 114.372 133.885 85.337  1.00 121.05 ? 344 ARG B NH2 1 
ATOM   6115 N  N   . PRO B 1 345 ? 108.237 137.630 87.745  1.00 116.64 ? 345 PRO B N   1 
ATOM   6116 C  CA  . PRO B 1 345 ? 108.788 138.979 87.910  1.00 116.64 ? 345 PRO B CA  1 
ATOM   6117 C  C   . PRO B 1 345 ? 110.231 139.069 87.440  1.00 116.64 ? 345 PRO B C   1 
ATOM   6118 O  O   . PRO B 1 345 ? 110.958 138.076 87.395  1.00 116.64 ? 345 PRO B O   1 
ATOM   6119 C  CB  . PRO B 1 345 ? 108.673 139.226 89.416  1.00 116.64 ? 345 PRO B CB  1 
ATOM   6120 C  CG  . PRO B 1 345 ? 107.609 138.307 89.870  1.00 116.64 ? 345 PRO B CG  1 
ATOM   6121 C  CD  . PRO B 1 345 ? 107.737 137.091 89.020  1.00 116.64 ? 345 PRO B CD  1 
ATOM   6122 N  N   . ALA B 1 346 ? 110.636 140.286 87.082  1.00 111.09 ? 346 ALA B N   1 
ATOM   6123 C  CA  . ALA B 1 346 ? 111.904 140.482 86.391  1.00 111.09 ? 346 ALA B CA  1 
ATOM   6124 C  C   . ALA B 1 346 ? 113.096 140.517 87.334  1.00 111.09 ? 346 ALA B C   1 
ATOM   6125 O  O   . ALA B 1 346 ? 114.236 140.606 86.868  1.00 111.09 ? 346 ALA B O   1 
ATOM   6126 C  CB  . ALA B 1 346 ? 111.857 141.768 85.568  1.00 111.09 ? 346 ALA B CB  1 
ATOM   6127 N  N   . PHE B 1 347 ? 112.876 140.458 88.644  1.00 107.07 ? 347 PHE B N   1 
ATOM   6128 C  CA  . PHE B 1 347 ? 113.998 140.389 89.566  1.00 107.07 ? 347 PHE B CA  1 
ATOM   6129 C  C   . PHE B 1 347 ? 114.483 138.967 89.788  1.00 107.07 ? 347 PHE B C   1 
ATOM   6130 O  O   . PHE B 1 347 ? 115.475 138.771 90.494  1.00 107.07 ? 347 PHE B O   1 
ATOM   6131 C  CB  . PHE B 1 347 ? 113.640 141.046 90.900  1.00 107.07 ? 347 PHE B CB  1 
ATOM   6132 C  CG  . PHE B 1 347 ? 112.762 140.212 91.790  1.00 107.07 ? 347 PHE B CG  1 
ATOM   6133 C  CD1 . PHE B 1 347 ? 113.299 139.493 92.849  1.00 107.07 ? 347 PHE B CD1 1 
ATOM   6134 C  CD2 . PHE B 1 347 ? 111.395 140.183 91.598  1.00 107.07 ? 347 PHE B CD2 1 
ATOM   6135 C  CE1 . PHE B 1 347 ? 112.495 138.736 93.668  1.00 107.07 ? 347 PHE B CE1 1 
ATOM   6136 C  CE2 . PHE B 1 347 ? 110.585 139.430 92.422  1.00 107.07 ? 347 PHE B CE2 1 
ATOM   6137 C  CZ  . PHE B 1 347 ? 111.137 138.707 93.455  1.00 107.07 ? 347 PHE B CZ  1 
ATOM   6138 N  N   . LEU B 1 348 ? 113.816 137.971 89.208  1.00 109.16 ? 348 LEU B N   1 
ATOM   6139 C  CA  . LEU B 1 348 ? 114.329 136.610 89.230  1.00 109.16 ? 348 LEU B CA  1 
ATOM   6140 C  C   . LEU B 1 348 ? 115.412 136.374 88.190  1.00 109.16 ? 348 LEU B C   1 
ATOM   6141 O  O   . LEU B 1 348 ? 115.952 135.267 88.120  1.00 109.16 ? 348 LEU B O   1 
ATOM   6142 C  CB  . LEU B 1 348 ? 113.192 135.610 89.031  1.00 109.16 ? 348 LEU B CB  1 
ATOM   6143 C  CG  . LEU B 1 348 ? 112.008 135.768 89.981  1.00 109.16 ? 348 LEU B CG  1 
ATOM   6144 C  CD1 . LEU B 1 348 ? 110.999 134.671 89.736  1.00 109.16 ? 348 LEU B CD1 1 
ATOM   6145 C  CD2 . LEU B 1 348 ? 112.471 135.736 91.422  1.00 109.16 ? 348 LEU B CD2 1 
ATOM   6146 N  N   . ASP B 1 349 ? 115.734 137.378 87.386  1.00 107.73 ? 349 ASP B N   1 
ATOM   6147 C  CA  . ASP B 1 349 ? 116.924 137.381 86.556  1.00 107.73 ? 349 ASP B CA  1 
ATOM   6148 C  C   . ASP B 1 349 ? 118.122 137.976 87.278  1.00 107.73 ? 349 ASP B C   1 
ATOM   6149 O  O   . ASP B 1 349 ? 119.200 138.075 86.688  1.00 107.73 ? 349 ASP B O   1 
ATOM   6150 C  CB  . ASP B 1 349 ? 116.659 138.167 85.275  1.00 107.73 ? 349 ASP B CB  1 
ATOM   6151 C  CG  . ASP B 1 349 ? 115.561 137.555 84.441  1.00 107.73 ? 349 ASP B CG  1 
ATOM   6152 O  OD1 . ASP B 1 349 ? 115.383 136.322 84.505  1.00 107.73 ? 349 ASP B OD1 1 
ATOM   6153 O  OD2 . ASP B 1 349 ? 114.867 138.307 83.729  1.00 107.73 ? 349 ASP B OD2 1 
ATOM   6154 N  N   . GLY B 1 350 ? 117.955 138.378 88.526  1.00 101.71 ? 350 GLY B N   1 
ATOM   6155 C  CA  . GLY B 1 350 ? 119.022 139.008 89.279  1.00 101.71 ? 350 GLY B CA  1 
ATOM   6156 C  C   . GLY B 1 350 ? 119.073 140.502 89.052  1.00 101.71 ? 350 GLY B C   1 
ATOM   6157 O  O   . GLY B 1 350 ? 118.986 140.996 87.931  1.00 101.71 ? 350 GLY B O   1 
ATOM   6158 N  N   . ILE B 1 351 ? 119.213 141.242 90.155  1.00 97.41  ? 351 ILE B N   1 
ATOM   6159 C  CA  . ILE B 1 351 ? 119.272 142.697 90.072  1.00 97.41  ? 351 ILE B CA  1 
ATOM   6160 C  C   . ILE B 1 351 ? 120.689 143.218 89.924  1.00 97.41  ? 351 ILE B C   1 
ATOM   6161 O  O   . ILE B 1 351 ? 120.860 144.412 89.636  1.00 97.41  ? 351 ILE B O   1 
ATOM   6162 C  CB  . ILE B 1 351 ? 118.610 143.358 91.295  1.00 97.41  ? 351 ILE B CB  1 
ATOM   6163 C  CG1 . ILE B 1 351 ? 119.289 142.907 92.580  1.00 97.41  ? 351 ILE B CG1 1 
ATOM   6164 C  CG2 . ILE B 1 351 ? 117.143 143.022 91.333  1.00 97.41  ? 351 ILE B CG2 1 
ATOM   6165 C  CD1 . ILE B 1 351 ? 118.859 143.686 93.783  1.00 97.41  ? 351 ILE B CD1 1 
ATOM   6166 N  N   . HIS B 1 352 ? 121.698 142.367 90.133  1.00 98.59  ? 352 HIS B N   1 
ATOM   6167 C  CA  . HIS B 1 352 ? 123.102 142.622 89.792  1.00 98.59  ? 352 HIS B CA  1 
ATOM   6168 C  C   . HIS B 1 352 ? 123.671 143.828 90.535  1.00 98.59  ? 352 HIS B C   1 
ATOM   6169 O  O   . HIS B 1 352 ? 124.148 144.788 89.931  1.00 98.59  ? 352 HIS B O   1 
ATOM   6170 C  CB  . HIS B 1 352 ? 123.281 142.798 88.282  1.00 98.59  ? 352 HIS B CB  1 
ATOM   6171 C  CG  . HIS B 1 352 ? 124.653 142.456 87.790  1.00 98.59  ? 352 HIS B CG  1 
ATOM   6172 N  ND1 . HIS B 1 352 ? 125.800 142.975 88.351  1.00 98.59  ? 352 HIS B ND1 1 
ATOM   6173 C  CD2 . HIS B 1 352 ? 125.059 141.686 86.754  1.00 98.59  ? 352 HIS B CD2 1 
ATOM   6174 C  CE1 . HIS B 1 352 ? 126.854 142.507 87.709  1.00 98.59  ? 352 HIS B CE1 1 
ATOM   6175 N  NE2 . HIS B 1 352 ? 126.432 141.726 86.732  1.00 98.59  ? 352 HIS B NE2 1 
ATOM   6176 N  N   . VAL B 1 353 ? 123.619 143.779 91.863  1.00 95.88  ? 353 VAL B N   1 
ATOM   6177 C  CA  . VAL B 1 353 ? 124.290 144.798 92.653  1.00 95.88  ? 353 VAL B CA  1 
ATOM   6178 C  C   . VAL B 1 353 ? 125.789 144.559 92.580  1.00 95.88  ? 353 VAL B C   1 
ATOM   6179 O  O   . VAL B 1 353 ? 126.261 143.426 92.731  1.00 95.88  ? 353 VAL B O   1 
ATOM   6180 C  CB  . VAL B 1 353 ? 123.779 144.779 94.104  1.00 95.88  ? 353 VAL B CB  1 
ATOM   6181 C  CG1 . VAL B 1 353 ? 124.599 145.685 94.994  1.00 95.88  ? 353 VAL B CG1 1 
ATOM   6182 C  CG2 . VAL B 1 353 ? 122.333 145.193 94.146  1.00 95.88  ? 353 VAL B CG2 1 
ATOM   6183 N  N   . ASP B 1 354 ? 126.538 145.613 92.283  1.00 98.27  ? 354 ASP B N   1 
ATOM   6184 C  CA  . ASP B 1 354 ? 127.985 145.523 92.312  1.00 98.27  ? 354 ASP B CA  1 
ATOM   6185 C  C   . ASP B 1 354 ? 128.451 145.301 93.748  1.00 98.27  ? 354 ASP B C   1 
ATOM   6186 O  O   . ASP B 1 354 ? 127.980 145.984 94.661  1.00 98.27  ? 354 ASP B O   1 
ATOM   6187 C  CB  . ASP B 1 354 ? 128.604 146.796 91.751  1.00 98.27  ? 354 ASP B CB  1 
ATOM   6188 C  CG  . ASP B 1 354 ? 130.099 146.698 91.601  1.00 98.27  ? 354 ASP B CG  1 
ATOM   6189 O  OD1 . ASP B 1 354 ? 130.567 145.782 90.899  1.00 98.27  ? 354 ASP B OD1 1 
ATOM   6190 O  OD2 . ASP B 1 354 ? 130.810 147.539 92.182  1.00 98.27  ? 354 ASP B OD2 1 
ATOM   6191 N  N   . PRO B 1 355 ? 129.358 144.348 93.982  1.00 95.17  ? 355 PRO B N   1 
ATOM   6192 C  CA  . PRO B 1 355 ? 129.730 144.011 95.365  1.00 95.17  ? 355 PRO B CA  1 
ATOM   6193 C  C   . PRO B 1 355 ? 130.540 145.077 96.075  1.00 95.17  ? 355 PRO B C   1 
ATOM   6194 O  O   . PRO B 1 355 ? 130.744 144.965 97.286  1.00 95.17  ? 355 PRO B O   1 
ATOM   6195 C  CB  . PRO B 1 355 ? 130.538 142.720 95.202  1.00 95.17  ? 355 PRO B CB  1 
ATOM   6196 C  CG  . PRO B 1 355 ? 130.125 142.176 93.897  1.00 95.17  ? 355 PRO B CG  1 
ATOM   6197 C  CD  . PRO B 1 355 ? 129.881 143.358 93.031  1.00 95.17  ? 355 PRO B CD  1 
ATOM   6198 N  N   . ASN B 1 356 ? 130.996 146.117 95.378  1.00 97.96  ? 356 ASN B N   1 
ATOM   6199 C  CA  . ASN B 1 356 ? 131.681 147.214 96.047  1.00 97.96  ? 356 ASN B CA  1 
ATOM   6200 C  C   . ASN B 1 356 ? 130.723 148.155 96.762  1.00 97.96  ? 356 ASN B C   1 
ATOM   6201 O  O   . ASN B 1 356 ? 131.182 149.080 97.437  1.00 97.96  ? 356 ASN B O   1 
ATOM   6202 C  CB  . ASN B 1 356 ? 132.516 147.997 95.042  1.00 97.96  ? 356 ASN B CB  1 
ATOM   6203 C  CG  . ASN B 1 356 ? 133.629 147.172 94.454  1.00 97.96  ? 356 ASN B CG  1 
ATOM   6204 O  OD1 . ASN B 1 356 ? 134.442 146.605 95.178  1.00 97.96  ? 356 ASN B OD1 1 
ATOM   6205 N  ND2 . ASN B 1 356 ? 133.669 147.091 93.133  1.00 97.96  ? 356 ASN B ND2 1 
ATOM   6206 N  N   . ASP B 1 357 ? 129.412 147.946 96.637  1.00 99.33  ? 357 ASP B N   1 
ATOM   6207 C  CA  . ASP B 1 357 ? 128.458 148.794 97.336  1.00 99.33  ? 357 ASP B CA  1 
ATOM   6208 C  C   . ASP B 1 357 ? 128.302 148.409 98.798  1.00 99.33  ? 357 ASP B C   1 
ATOM   6209 O  O   . ASP B 1 357 ? 127.596 149.106 99.533  1.00 99.33  ? 357 ASP B O   1 
ATOM   6210 C  CB  . ASP B 1 357 ? 127.100 148.746 96.642  1.00 99.33  ? 357 ASP B CB  1 
ATOM   6211 C  CG  . ASP B 1 357 ? 127.176 149.167 95.196  1.00 99.33  ? 357 ASP B CG  1 
ATOM   6212 O  OD1 . ASP B 1 357 ? 128.267 149.576 94.755  1.00 99.33  ? 357 ASP B OD1 1 
ATOM   6213 O  OD2 . ASP B 1 357 ? 126.144 149.101 94.499  1.00 99.33  ? 357 ASP B OD2 1 
ATOM   6214 N  N   . VAL B 1 358 ? 128.943 147.325 99.243  1.00 95.58  ? 358 VAL B N   1 
ATOM   6215 C  CA  . VAL B 1 358 ? 128.890 146.970 100.656 1.00 95.58  ? 358 VAL B CA  1 
ATOM   6216 C  C   . VAL B 1 358 ? 129.822 147.849 101.470 1.00 95.58  ? 358 VAL B C   1 
ATOM   6217 O  O   . VAL B 1 358 ? 129.707 147.909 102.696 1.00 95.58  ? 358 VAL B O   1 
ATOM   6218 C  CB  . VAL B 1 358 ? 129.213 145.479 100.863 1.00 95.58  ? 358 VAL B CB  1 
ATOM   6219 C  CG1 . VAL B 1 358 ? 128.375 144.635 99.951  1.00 95.58  ? 358 VAL B CG1 1 
ATOM   6220 C  CG2 . VAL B 1 358 ? 130.684 145.208 100.637 1.00 95.58  ? 358 VAL B CG2 1 
ATOM   6221 N  N   . PHE B 1 359 ? 130.739 148.565 100.811 1.00 96.65  ? 359 PHE B N   1 
ATOM   6222 C  CA  . PHE B 1 359 ? 131.680 149.425 101.522 1.00 96.65  ? 359 PHE B CA  1 
ATOM   6223 C  C   . PHE B 1 359 ? 130.980 150.621 102.146 1.00 96.65  ? 359 PHE B C   1 
ATOM   6224 O  O   . PHE B 1 359 ? 131.500 151.238 103.081 1.00 96.65  ? 359 PHE B O   1 
ATOM   6225 C  CB  . PHE B 1 359 ? 132.770 149.903 100.570 1.00 96.65  ? 359 PHE B CB  1 
ATOM   6226 C  CG  . PHE B 1 359 ? 133.871 148.921 100.372 1.00 96.65  ? 359 PHE B CG  1 
ATOM   6227 C  CD1 . PHE B 1 359 ? 135.004 148.972 101.157 1.00 96.65  ? 359 PHE B CD1 1 
ATOM   6228 C  CD2 . PHE B 1 359 ? 133.777 147.952 99.397  1.00 96.65  ? 359 PHE B CD2 1 
ATOM   6229 C  CE1 . PHE B 1 359 ? 136.023 148.070 100.973 1.00 96.65  ? 359 PHE B CE1 1 
ATOM   6230 C  CE2 . PHE B 1 359 ? 134.792 147.048 99.210  1.00 96.65  ? 359 PHE B CE2 1 
ATOM   6231 C  CZ  . PHE B 1 359 ? 135.917 147.108 100.000 1.00 96.65  ? 359 PHE B CZ  1 
ATOM   6232 N  N   . ASP B 1 360 ? 129.800 150.965 101.638 1.00 100.79 ? 360 ASP B N   1 
ATOM   6233 C  CA  . ASP B 1 360 ? 129.070 152.102 102.175 1.00 100.79 ? 360 ASP B CA  1 
ATOM   6234 C  C   . ASP B 1 360 ? 128.402 151.751 103.495 1.00 100.79 ? 360 ASP B C   1 
ATOM   6235 O  O   . ASP B 1 360 ? 128.298 152.597 104.389 1.00 100.79 ? 360 ASP B O   1 
ATOM   6236 C  CB  . ASP B 1 360 ? 128.031 152.564 101.159 1.00 100.79 ? 360 ASP B CB  1 
ATOM   6237 C  CG  . ASP B 1 360 ? 128.655 152.981 99.847  1.00 100.79 ? 360 ASP B CG  1 
ATOM   6238 O  OD1 . ASP B 1 360 ? 129.830 153.401 99.854  1.00 100.79 ? 360 ASP B OD1 1 
ATOM   6239 O  OD2 . ASP B 1 360 ? 127.972 152.887 98.805  1.00 100.79 ? 360 ASP B OD2 1 
ATOM   6240 N  N   . VAL B 1 361 ? 127.951 150.503 103.641 1.00 95.29  ? 361 VAL B N   1 
ATOM   6241 C  CA  . VAL B 1 361 ? 127.078 150.127 104.743 1.00 95.29  ? 361 VAL B CA  1 
ATOM   6242 C  C   . VAL B 1 361 ? 127.649 149.023 105.616 1.00 95.29  ? 361 VAL B C   1 
ATOM   6243 O  O   . VAL B 1 361 ? 126.894 148.421 106.383 1.00 95.29  ? 361 VAL B O   1 
ATOM   6244 C  CB  . VAL B 1 361 ? 125.695 149.697 104.220 1.00 95.29  ? 361 VAL B CB  1 
ATOM   6245 C  CG1 . VAL B 1 361 ? 124.970 150.864 103.597 1.00 95.29  ? 361 VAL B CG1 1 
ATOM   6246 C  CG2 . VAL B 1 361 ? 125.840 148.576 103.218 1.00 95.29  ? 361 VAL B CG2 1 
ATOM   6247 N  N   . ILE B 1 362 ? 128.951 148.740 105.542 1.00 94.15  ? 362 ILE B N   1 
ATOM   6248 C  CA  . ILE B 1 362 ? 129.481 147.566 106.232 1.00 94.15  ? 362 ILE B CA  1 
ATOM   6249 C  C   . ILE B 1 362 ? 129.579 147.771 107.739 1.00 94.15  ? 362 ILE B C   1 
ATOM   6250 O  O   . ILE B 1 362 ? 129.687 146.797 108.487 1.00 94.15  ? 362 ILE B O   1 
ATOM   6251 C  CB  . ILE B 1 362 ? 130.849 147.158 105.638 1.00 94.15  ? 362 ILE B CB  1 
ATOM   6252 C  CG1 . ILE B 1 362 ? 131.103 145.659 105.825 1.00 94.15  ? 362 ILE B CG1 1 
ATOM   6253 C  CG2 . ILE B 1 362 ? 131.977 147.980 106.229 1.00 94.15  ? 362 ILE B CG2 1 
ATOM   6254 C  CD1 . ILE B 1 362 ? 130.064 144.775 105.187 1.00 94.15  ? 362 ILE B CD1 1 
ATOM   6255 N  N   . GLU B 1 363 ? 129.502 149.011 108.219 1.00 95.53  ? 363 GLU B N   1 
ATOM   6256 C  CA  . GLU B 1 363 ? 129.615 149.225 109.656 1.00 95.53  ? 363 GLU B CA  1 
ATOM   6257 C  C   . GLU B 1 363 ? 128.293 148.955 110.358 1.00 95.53  ? 363 GLU B C   1 
ATOM   6258 O  O   . GLU B 1 363 ? 128.231 148.941 111.591 1.00 95.53  ? 363 GLU B O   1 
ATOM   6259 C  CB  . GLU B 1 363 ? 130.108 150.640 109.944 1.00 95.53  ? 363 GLU B CB  1 
ATOM   6260 C  CG  . GLU B 1 363 ? 129.076 151.725 109.720 1.00 95.53  ? 363 GLU B CG  1 
ATOM   6261 C  CD  . GLU B 1 363 ? 129.020 152.187 108.280 1.00 95.53  ? 363 GLU B CD  1 
ATOM   6262 O  OE1 . GLU B 1 363 ? 128.039 152.866 107.910 1.00 95.53  ? 363 GLU B OE1 1 
ATOM   6263 O  OE2 . GLU B 1 363 ? 129.957 151.871 107.518 1.00 95.53  ? 363 GLU B OE2 1 
ATOM   6264 N  N   . ASN B 1 364 ? 127.226 148.737 109.595 1.00 89.51  ? 364 ASN B N   1 
ATOM   6265 C  CA  . ASN B 1 364 ? 125.921 148.403 110.143 1.00 89.51  ? 364 ASN B CA  1 
ATOM   6266 C  C   . ASN B 1 364 ? 125.455 147.009 109.758 1.00 89.51  ? 364 ASN B C   1 
ATOM   6267 O  O   . ASN B 1 364 ? 124.371 146.600 110.175 1.00 89.51  ? 364 ASN B O   1 
ATOM   6268 C  CB  . ASN B 1 364 ? 124.882 149.427 109.695 1.00 89.51  ? 364 ASN B CB  1 
ATOM   6269 C  CG  . ASN B 1 364 ? 125.181 150.813 110.201 1.00 89.51  ? 364 ASN B CG  1 
ATOM   6270 O  OD1 . ASN B 1 364 ? 125.131 151.071 111.399 1.00 89.51  ? 364 ASN B OD1 1 
ATOM   6271 N  ND2 . ASN B 1 364 ? 125.493 151.719 109.288 1.00 89.51  ? 364 ASN B ND2 1 
ATOM   6272 N  N   . VAL B 1 365 ? 126.230 146.277 108.967 1.00 84.68  ? 365 VAL B N   1 
ATOM   6273 C  CA  . VAL B 1 365 ? 125.884 144.903 108.628 1.00 84.68  ? 365 VAL B CA  1 
ATOM   6274 C  C   . VAL B 1 365 ? 126.371 144.000 109.747 1.00 84.68  ? 365 VAL B C   1 
ATOM   6275 O  O   . VAL B 1 365 ? 127.570 143.935 110.027 1.00 84.68  ? 365 VAL B O   1 
ATOM   6276 C  CB  . VAL B 1 365 ? 126.490 144.488 107.284 1.00 84.68  ? 365 VAL B CB  1 
ATOM   6277 C  CG1 . VAL B 1 365 ? 126.266 143.018 107.051 1.00 84.68  ? 365 VAL B CG1 1 
ATOM   6278 C  CG2 . VAL B 1 365 ? 125.865 145.276 106.169 1.00 84.68  ? 365 VAL B CG2 1 
ATOM   6279 N  N   . VAL B 1 366 ? 125.442 143.307 110.393 1.00 80.11  ? 366 VAL B N   1 
ATOM   6280 C  CA  . VAL B 1 366 ? 125.778 142.431 111.503 1.00 80.11  ? 366 VAL B CA  1 
ATOM   6281 C  C   . VAL B 1 366 ? 125.686 140.961 111.138 1.00 80.11  ? 366 VAL B C   1 
ATOM   6282 O  O   . VAL B 1 366 ? 126.203 140.123 111.890 1.00 80.11  ? 366 VAL B O   1 
ATOM   6283 C  CB  . VAL B 1 366 ? 124.895 142.728 112.731 1.00 80.11  ? 366 VAL B CB  1 
ATOM   6284 C  CG1 . VAL B 1 366 ? 125.050 144.168 113.152 1.00 80.11  ? 366 VAL B CG1 1 
ATOM   6285 C  CG2 . VAL B 1 366 ? 123.451 142.424 112.424 1.00 80.11  ? 366 VAL B CG2 1 
ATOM   6286 N  N   . PHE B 1 367 ? 125.079 140.620 110.010 1.00 75.37  ? 367 PHE B N   1 
ATOM   6287 C  CA  . PHE B 1 367 ? 124.775 139.241 109.689 1.00 75.37  ? 367 PHE B CA  1 
ATOM   6288 C  C   . PHE B 1 367 ? 124.505 139.154 108.202 1.00 75.37  ? 367 PHE B C   1 
ATOM   6289 O  O   . PHE B 1 367 ? 123.927 140.067 107.615 1.00 75.37  ? 367 PHE B O   1 
ATOM   6290 C  CB  . PHE B 1 367 ? 123.567 138.762 110.484 1.00 75.37  ? 367 PHE B CB  1 
ATOM   6291 C  CG  . PHE B 1 367 ? 123.364 137.296 110.452 1.00 75.37  ? 367 PHE B CG  1 
ATOM   6292 C  CD1 . PHE B 1 367 ? 124.157 136.464 111.204 1.00 75.37  ? 367 PHE B CD1 1 
ATOM   6293 C  CD2 . PHE B 1 367 ? 122.364 136.748 109.684 1.00 75.37  ? 367 PHE B CD2 1 
ATOM   6294 C  CE1 . PHE B 1 367 ? 123.959 135.117 111.181 1.00 75.37  ? 367 PHE B CE1 1 
ATOM   6295 C  CE2 . PHE B 1 367 ? 122.167 135.409 109.659 1.00 75.37  ? 367 PHE B CE2 1 
ATOM   6296 C  CZ  . PHE B 1 367 ? 122.962 134.595 110.410 1.00 75.37  ? 367 PHE B CZ  1 
ATOM   6297 N  N   . ILE B 1 368 ? 124.938 138.060 107.589 1.00 75.89  ? 368 ILE B N   1 
ATOM   6298 C  CA  . ILE B 1 368 ? 124.804 137.878 106.152 1.00 75.89  ? 368 ILE B CA  1 
ATOM   6299 C  C   . ILE B 1 368 ? 124.216 136.504 105.880 1.00 75.89  ? 368 ILE B C   1 
ATOM   6300 O  O   . ILE B 1 368 ? 124.758 135.492 106.332 1.00 75.89  ? 368 ILE B O   1 
ATOM   6301 C  CB  . ILE B 1 368 ? 126.149 138.051 105.425 1.00 75.89  ? 368 ILE B CB  1 
ATOM   6302 C  CG1 . ILE B 1 368 ? 126.535 139.521 105.397 1.00 75.89  ? 368 ILE B CG1 1 
ATOM   6303 C  CG2 . ILE B 1 368 ? 126.056 137.553 104.018 1.00 75.89  ? 368 ILE B CG2 1 
ATOM   6304 C  CD1 . ILE B 1 368 ? 127.813 139.792 104.705 1.00 75.89  ? 368 ILE B CD1 1 
ATOM   6305 N  N   . GLN B 1 369 ? 123.109 136.471 105.151 1.00 79.70  ? 369 GLN B N   1 
ATOM   6306 C  CA  . GLN B 1 369 ? 122.501 135.233 104.692 1.00 79.70  ? 369 GLN B CA  1 
ATOM   6307 C  C   . GLN B 1 369 ? 123.072 134.895 103.325 1.00 79.70  ? 369 GLN B C   1 
ATOM   6308 O  O   . GLN B 1 369 ? 122.783 135.580 102.342 1.00 79.70  ? 369 GLN B O   1 
ATOM   6309 C  CB  . GLN B 1 369 ? 120.986 135.370 104.621 1.00 79.70  ? 369 GLN B CB  1 
ATOM   6310 C  CG  . GLN B 1 369 ? 120.305 135.246 105.949 1.00 79.70  ? 369 GLN B CG  1 
ATOM   6311 C  CD  . GLN B 1 369 ? 118.839 135.566 105.868 1.00 79.70  ? 369 GLN B CD  1 
ATOM   6312 O  OE1 . GLN B 1 369 ? 118.295 135.749 104.785 1.00 79.70  ? 369 GLN B OE1 1 
ATOM   6313 N  NE2 . GLN B 1 369 ? 118.188 135.645 107.017 1.00 79.70  ? 369 GLN B NE2 1 
ATOM   6314 N  N   . ALA B 1 370 ? 123.876 133.842 103.262 1.00 79.06  ? 370 ALA B N   1 
ATOM   6315 C  CA  . ALA B 1 370 ? 124.492 133.415 102.012 1.00 79.06  ? 370 ALA B CA  1 
ATOM   6316 C  C   . ALA B 1 370 ? 123.443 132.697 101.179 1.00 79.06  ? 370 ALA B C   1 
ATOM   6317 O  O   . ALA B 1 370 ? 123.237 131.491 101.317 1.00 79.06  ? 370 ALA B O   1 
ATOM   6318 C  CB  . ALA B 1 370 ? 125.694 132.525 102.290 1.00 79.06  ? 370 ALA B CB  1 
ATOM   6319 N  N   . LYS B 1 371 ? 122.781 133.444 100.306 1.00 81.15  ? 371 LYS B N   1 
ATOM   6320 C  CA  . LYS B 1 371 ? 121.691 132.948 99.481  1.00 81.15  ? 371 LYS B CA  1 
ATOM   6321 C  C   . LYS B 1 371 ? 122.253 132.351 98.202  1.00 81.15  ? 371 LYS B C   1 
ATOM   6322 O  O   . LYS B 1 371 ? 123.112 132.958 97.561  1.00 81.15  ? 371 LYS B O   1 
ATOM   6323 C  CB  . LYS B 1 371 ? 120.728 134.086 99.156  1.00 81.15  ? 371 LYS B CB  1 
ATOM   6324 C  CG  . LYS B 1 371 ? 119.622 133.744 98.201  1.00 81.15  ? 371 LYS B CG  1 
ATOM   6325 C  CD  . LYS B 1 371 ? 118.510 133.024 98.907  1.00 81.15  ? 371 LYS B CD  1 
ATOM   6326 C  CE  . LYS B 1 371 ? 117.803 133.935 99.875  1.00 81.15  ? 371 LYS B CE  1 
ATOM   6327 N  NZ  . LYS B 1 371 ? 117.180 135.087 99.187  1.00 81.15  ? 371 LYS B NZ  1 
ATOM   6328 N  N   . PHE B 1 372 ? 121.772 131.168 97.835  1.00 76.26  ? 372 PHE B N   1 
ATOM   6329 C  CA  . PHE B 1 372 ? 122.220 130.512 96.618  1.00 76.26  ? 372 PHE B CA  1 
ATOM   6330 C  C   . PHE B 1 372 ? 121.132 129.569 96.138  1.00 76.26  ? 372 PHE B C   1 
ATOM   6331 O  O   . PHE B 1 372 ? 120.218 129.217 96.883  1.00 76.26  ? 372 PHE B O   1 
ATOM   6332 C  CB  . PHE B 1 372 ? 123.539 129.763 96.828  1.00 76.26  ? 372 PHE B CB  1 
ATOM   6333 C  CG  . PHE B 1 372 ? 123.397 128.457 97.545  1.00 76.26  ? 372 PHE B CG  1 
ATOM   6334 C  CD1 . PHE B 1 372 ? 123.126 128.418 98.898  1.00 76.26  ? 372 PHE B CD1 1 
ATOM   6335 C  CD2 . PHE B 1 372 ? 123.567 127.267 96.872  1.00 76.26  ? 372 PHE B CD2 1 
ATOM   6336 C  CE1 . PHE B 1 372 ? 123.009 127.225 99.554  1.00 76.26  ? 372 PHE B CE1 1 
ATOM   6337 C  CE2 . PHE B 1 372 ? 123.447 126.075 97.528  1.00 76.26  ? 372 PHE B CE2 1 
ATOM   6338 C  CZ  . PHE B 1 372 ? 123.170 126.056 98.870  1.00 76.26  ? 372 PHE B CZ  1 
ATOM   6339 N  N   . HIS B 1 373 ? 121.241 129.162 94.880  1.00 80.14  ? 373 HIS B N   1 
ATOM   6340 C  CA  . HIS B 1 373 ? 120.231 128.326 94.253  1.00 80.14  ? 373 HIS B CA  1 
ATOM   6341 C  C   . HIS B 1 373 ? 120.766 127.038 93.662  1.00 80.14  ? 373 HIS B C   1 
ATOM   6342 O  O   . HIS B 1 373 ? 120.067 126.028 93.714  1.00 80.14  ? 373 HIS B O   1 
ATOM   6343 C  CB  . HIS B 1 373 ? 119.507 129.098 93.145  1.00 80.14  ? 373 HIS B CB  1 
ATOM   6344 C  CG  . HIS B 1 373 ? 118.851 130.351 93.619  1.00 80.14  ? 373 HIS B CG  1 
ATOM   6345 N  ND1 . HIS B 1 373 ? 119.549 131.516 93.845  1.00 80.14  ? 373 HIS B ND1 1 
ATOM   6346 C  CD2 . HIS B 1 373 ? 117.562 130.621 93.920  1.00 80.14  ? 373 HIS B CD2 1 
ATOM   6347 C  CE1 . HIS B 1 373 ? 118.718 132.449 94.265  1.00 80.14  ? 373 HIS B CE1 1 
ATOM   6348 N  NE2 . HIS B 1 373 ? 117.506 131.932 94.321  1.00 80.14  ? 373 HIS B NE2 1 
ATOM   6349 N  N   . ASP B 1 374 ? 121.972 127.036 93.103  1.00 81.89  ? 374 ASP B N   1 
ATOM   6350 C  CA  . ASP B 1 374 ? 122.464 125.850 92.420  1.00 81.89  ? 374 ASP B CA  1 
ATOM   6351 C  C   . ASP B 1 374 ? 123.979 125.866 92.378  1.00 81.89  ? 374 ASP B C   1 
ATOM   6352 O  O   . ASP B 1 374 ? 124.578 126.850 91.951  1.00 81.89  ? 374 ASP B O   1 
ATOM   6353 C  CB  . ASP B 1 374 ? 121.910 125.769 91.001  1.00 81.89  ? 374 ASP B CB  1 
ATOM   6354 C  CG  . ASP B 1 374 ? 121.957 124.374 90.445  1.00 81.89  ? 374 ASP B CG  1 
ATOM   6355 O  OD1 . ASP B 1 374 ? 121.980 123.417 91.243  1.00 81.89  ? 374 ASP B OD1 1 
ATOM   6356 O  OD2 . ASP B 1 374 ? 121.976 124.230 89.207  1.00 81.89  ? 374 ASP B OD2 1 
ATOM   6357 N  N   . ILE B 1 375 ? 124.588 124.775 92.831  1.00 79.79  ? 375 ILE B N   1 
ATOM   6358 C  CA  . ILE B 1 375 ? 126.022 124.540 92.709  1.00 79.79  ? 375 ILE B CA  1 
ATOM   6359 C  C   . ILE B 1 375 ? 126.204 123.122 92.192  1.00 79.79  ? 375 ILE B C   1 
ATOM   6360 O  O   . ILE B 1 375 ? 125.670 122.176 92.778  1.00 79.79  ? 375 ILE B O   1 
ATOM   6361 C  CB  . ILE B 1 375 ? 126.757 124.733 94.051  1.00 79.79  ? 375 ILE B CB  1 
ATOM   6362 C  CG1 . ILE B 1 375 ? 126.677 126.186 94.504  1.00 79.79  ? 375 ILE B CG1 1 
ATOM   6363 C  CG2 . ILE B 1 375 ? 128.204 124.342 93.927  1.00 79.79  ? 375 ILE B CG2 1 
ATOM   6364 C  CD1 . ILE B 1 375 ? 127.112 126.409 95.898  1.00 79.79  ? 375 ILE B CD1 1 
ATOM   6365 N  N   . ASP B 1 376 ? 126.935 122.970 91.093  1.00 85.60  ? 376 ASP B N   1 
ATOM   6366 C  CA  . ASP B 1 376 ? 127.080 121.669 90.459  1.00 85.60  ? 376 ASP B CA  1 
ATOM   6367 C  C   . ASP B 1 376 ? 128.299 120.933 91.018  1.00 85.60  ? 376 ASP B C   1 
ATOM   6368 O  O   . ASP B 1 376 ? 128.892 121.334 92.020  1.00 85.60  ? 376 ASP B O   1 
ATOM   6369 C  CB  . ASP B 1 376 ? 127.156 121.823 88.945  1.00 85.60  ? 376 ASP B CB  1 
ATOM   6370 C  CG  . ASP B 1 376 ? 128.416 122.509 88.495  1.00 85.60  ? 376 ASP B CG  1 
ATOM   6371 O  OD1 . ASP B 1 376 ? 128.929 123.349 89.250  1.00 85.60  ? 376 ASP B OD1 1 
ATOM   6372 O  OD2 . ASP B 1 376 ? 128.897 122.213 87.386  1.00 85.60  ? 376 ASP B OD2 1 
ATOM   6373 N  N   . GLU B 1 377 ? 128.696 119.848 90.353  1.00 85.14  ? 377 GLU B N   1 
ATOM   6374 C  CA  . GLU B 1 377 ? 129.733 118.971 90.881  1.00 85.14  ? 377 GLU B CA  1 
ATOM   6375 C  C   . GLU B 1 377 ? 131.137 119.525 90.705  1.00 85.14  ? 377 GLU B C   1 
ATOM   6376 O  O   . GLU B 1 377 ? 132.079 118.963 91.268  1.00 85.14  ? 377 GLU B O   1 
ATOM   6377 C  CB  . GLU B 1 377 ? 129.645 117.606 90.218  1.00 85.14  ? 377 GLU B CB  1 
ATOM   6378 C  CG  . GLU B 1 377 ? 128.446 116.820 90.655  1.00 85.14  ? 377 GLU B CG  1 
ATOM   6379 C  CD  . GLU B 1 377 ? 127.277 116.990 89.723  1.00 85.14  ? 377 GLU B CD  1 
ATOM   6380 O  OE1 . GLU B 1 377 ? 127.420 117.723 88.723  1.00 85.14  ? 377 GLU B OE1 1 
ATOM   6381 O  OE2 . GLU B 1 377 ? 126.217 116.386 89.987  1.00 85.14  ? 377 GLU B OE2 1 
ATOM   6382 N  N   . GLU B 1 378 ? 131.309 120.594 89.937  1.00 88.20  ? 378 GLU B N   1 
ATOM   6383 C  CA  . GLU B 1 378 ? 132.601 121.246 89.809  1.00 88.20  ? 378 GLU B CA  1 
ATOM   6384 C  C   . GLU B 1 378 ? 132.756 122.409 90.769  1.00 88.20  ? 378 GLU B C   1 
ATOM   6385 O  O   . GLU B 1 378 ? 133.706 123.184 90.626  1.00 88.20  ? 378 GLU B O   1 
ATOM   6386 C  CB  . GLU B 1 378 ? 132.814 121.730 88.379  1.00 88.20  ? 378 GLU B CB  1 
ATOM   6387 C  CG  . GLU B 1 378 ? 133.539 120.742 87.507  1.00 88.20  ? 378 GLU B CG  1 
ATOM   6388 C  CD  . GLU B 1 378 ? 132.724 119.498 87.255  1.00 88.20  ? 378 GLU B CD  1 
ATOM   6389 O  OE1 . GLU B 1 378 ? 131.493 119.622 87.087  1.00 88.20  ? 378 GLU B OE1 1 
ATOM   6390 O  OE2 . GLU B 1 378 ? 133.309 118.397 87.231  1.00 88.20  ? 378 GLU B OE2 1 
ATOM   6391 N  N   . LEU B 1 379 ? 131.851 122.522 91.747  1.00 83.19  ? 379 LEU B N   1 
ATOM   6392 C  CA  . LEU B 1 379 ? 131.752 123.651 92.672  1.00 83.19  ? 379 LEU B CA  1 
ATOM   6393 C  C   . LEU B 1 379 ? 131.660 124.976 91.926  1.00 83.19  ? 379 LEU B C   1 
ATOM   6394 O  O   . LEU B 1 379 ? 132.392 125.923 92.210  1.00 83.19  ? 379 LEU B O   1 
ATOM   6395 C  CB  . LEU B 1 379 ? 132.905 123.668 93.678  1.00 83.19  ? 379 LEU B CB  1 
ATOM   6396 C  CG  . LEU B 1 379 ? 132.916 122.586 94.753  1.00 83.19  ? 379 LEU B CG  1 
ATOM   6397 C  CD1 . LEU B 1 379 ? 133.949 122.923 95.794  1.00 83.19  ? 379 LEU B CD1 1 
ATOM   6398 C  CD2 . LEU B 1 379 ? 131.558 122.443 95.384  1.00 83.19  ? 379 LEU B CD2 1 
ATOM   6399 N  N   . ASP B 1 380 ? 130.767 125.038 90.950  1.00 87.43  ? 380 ASP B N   1 
ATOM   6400 C  CA  . ASP B 1 380 ? 130.504 126.256 90.200  1.00 87.43  ? 380 ASP B CA  1 
ATOM   6401 C  C   . ASP B 1 380 ? 129.090 126.717 90.515  1.00 87.43  ? 380 ASP B C   1 
ATOM   6402 O  O   . ASP B 1 380 ? 128.125 125.997 90.245  1.00 87.43  ? 380 ASP B O   1 
ATOM   6403 C  CB  . ASP B 1 380 ? 130.681 126.025 88.701  1.00 87.43  ? 380 ASP B CB  1 
ATOM   6404 C  CG  . ASP B 1 380 ? 130.314 127.236 87.877  1.00 87.43  ? 380 ASP B CG  1 
ATOM   6405 O  OD1 . ASP B 1 380 ? 129.770 127.052 86.771  1.00 87.43  ? 380 ASP B OD1 1 
ATOM   6406 O  OD2 . ASP B 1 380 ? 130.579 128.371 88.321  1.00 87.43  ? 380 ASP B OD2 1 
ATOM   6407 N  N   . ASP B 1 381 ? 128.971 127.903 91.097  1.00 87.38  ? 381 ASP B N   1 
ATOM   6408 C  CA  . ASP B 1 381 ? 127.665 128.481 91.365  1.00 87.38  ? 381 ASP B CA  1 
ATOM   6409 C  C   . ASP B 1 381 ? 127.063 128.990 90.067  1.00 87.38  ? 381 ASP B C   1 
ATOM   6410 O  O   . ASP B 1 381 ? 127.767 129.536 89.215  1.00 87.38  ? 381 ASP B O   1 
ATOM   6411 C  CB  . ASP B 1 381 ? 127.777 129.614 92.380  1.00 87.38  ? 381 ASP B CB  1 
ATOM   6412 C  CG  . ASP B 1 381 ? 126.458 129.921 93.062  1.00 87.38  ? 381 ASP B CG  1 
ATOM   6413 O  OD1 . ASP B 1 381 ? 125.488 130.289 92.371  1.00 87.38  ? 381 ASP B OD1 1 
ATOM   6414 O  OD2 . ASP B 1 381 ? 126.387 129.799 94.299  1.00 87.38  ? 381 ASP B OD2 1 
ATOM   6415 N  N   . LYS B 1 382 ? 125.758 128.817 89.923  1.00 88.34  ? 382 LYS B N   1 
ATOM   6416 C  CA  . LYS B 1 382 ? 125.070 129.184 88.700  1.00 88.34  ? 382 LYS B CA  1 
ATOM   6417 C  C   . LYS B 1 382 ? 124.400 130.545 88.770  1.00 88.34  ? 382 LYS B C   1 
ATOM   6418 O  O   . LYS B 1 382 ? 123.924 131.031 87.741  1.00 88.34  ? 382 LYS B O   1 
ATOM   6419 C  CB  . LYS B 1 382 ? 124.025 128.125 88.357  1.00 88.34  ? 382 LYS B CB  1 
ATOM   6420 C  CG  . LYS B 1 382 ? 124.596 126.742 88.187  1.00 88.34  ? 382 LYS B CG  1 
ATOM   6421 C  CD  . LYS B 1 382 ? 125.663 126.735 87.120  1.00 88.34  ? 382 LYS B CD  1 
ATOM   6422 C  CE  . LYS B 1 382 ? 126.237 125.356 86.923  1.00 88.34  ? 382 LYS B CE  1 
ATOM   6423 N  NZ  . LYS B 1 382 ? 127.457 125.410 86.083  1.00 88.34  ? 382 LYS B NZ  1 
ATOM   6424 N  N   . GLN B 1 383 ? 124.341 131.170 89.939  1.00 90.19  ? 383 GLN B N   1 
ATOM   6425 C  CA  . GLN B 1 383 ? 123.635 132.438 90.033  1.00 90.19  ? 383 GLN B CA  1 
ATOM   6426 C  C   . GLN B 1 383 ? 124.433 133.534 90.721  1.00 90.19  ? 383 GLN B C   1 
ATOM   6427 O  O   . GLN B 1 383 ? 124.261 134.704 90.387  1.00 90.19  ? 383 GLN B O   1 
ATOM   6428 C  CB  . GLN B 1 383 ? 122.307 132.244 90.760  1.00 90.19  ? 383 GLN B CB  1 
ATOM   6429 C  CG  . GLN B 1 383 ? 121.157 131.880 89.856  1.00 90.19  ? 383 GLN B CG  1 
ATOM   6430 C  CD  . GLN B 1 383 ? 121.082 130.401 89.586  1.00 90.19  ? 383 GLN B CD  1 
ATOM   6431 O  OE1 . GLN B 1 383 ? 121.398 129.591 90.447  1.00 90.19  ? 383 GLN B OE1 1 
ATOM   6432 N  NE2 . GLN B 1 383 ? 120.662 130.038 88.388  1.00 90.19  ? 383 GLN B NE2 1 
ATOM   6433 N  N   . ILE B 1 384 ? 125.294 133.194 91.667  1.00 85.71  ? 384 ILE B N   1 
ATOM   6434 C  CA  . ILE B 1 384 ? 125.981 134.179 92.499  1.00 85.71  ? 384 ILE B CA  1 
ATOM   6435 C  C   . ILE B 1 384 ? 127.463 134.182 92.135  1.00 85.71  ? 384 ILE B C   1 
ATOM   6436 O  O   . ILE B 1 384 ? 128.080 133.114 92.113  1.00 85.71  ? 384 ILE B O   1 
ATOM   6437 C  CB  . ILE B 1 384 ? 125.799 133.891 93.999  1.00 85.71  ? 384 ILE B CB  1 
ATOM   6438 C  CG1 . ILE B 1 384 ? 124.376 133.417 94.294  1.00 85.71  ? 384 ILE B CG1 1 
ATOM   6439 C  CG2 . ILE B 1 384 ? 126.154 135.115 94.820  1.00 85.71  ? 384 ILE B CG2 1 
ATOM   6440 C  CD1 . ILE B 1 384 ? 123.328 134.478 94.174  1.00 85.71  ? 384 ILE B CD1 1 
ATOM   6441 N  N   . PRO B 1 385 ? 128.052 135.332 91.850  1.00 86.81  ? 385 PRO B N   1 
ATOM   6442 C  CA  . PRO B 1 385 ? 129.506 135.401 91.656  1.00 86.81  ? 385 PRO B CA  1 
ATOM   6443 C  C   . PRO B 1 385 ? 130.261 135.461 92.972  1.00 86.81  ? 385 PRO B C   1 
ATOM   6444 O  O   . PRO B 1 385 ? 130.564 136.549 93.464  1.00 86.81  ? 385 PRO B O   1 
ATOM   6445 C  CB  . PRO B 1 385 ? 129.686 136.687 90.845  1.00 86.81  ? 385 PRO B CB  1 
ATOM   6446 C  CG  . PRO B 1 385 ? 128.503 137.509 91.170  1.00 86.81  ? 385 PRO B CG  1 
ATOM   6447 C  CD  . PRO B 1 385 ? 127.381 136.588 91.496  1.00 86.81  ? 385 PRO B CD  1 
ATOM   6448 N  N   . TRP B 1 386 ? 130.572 134.298 93.547  1.00 82.35  ? 386 TRP B N   1 
ATOM   6449 C  CA  . TRP B 1 386 ? 131.007 134.243 94.938  1.00 82.35  ? 386 TRP B CA  1 
ATOM   6450 C  C   . TRP B 1 386 ? 132.391 134.835 95.146  1.00 82.35  ? 386 TRP B C   1 
ATOM   6451 O  O   . TRP B 1 386 ? 132.696 135.325 96.235  1.00 82.35  ? 386 TRP B O   1 
ATOM   6452 C  CB  . TRP B 1 386 ? 130.980 132.806 95.437  1.00 82.35  ? 386 TRP B CB  1 
ATOM   6453 C  CG  . TRP B 1 386 ? 129.645 132.394 95.885  1.00 82.35  ? 386 TRP B CG  1 
ATOM   6454 C  CD1 . TRP B 1 386 ? 128.846 131.474 95.300  1.00 82.35  ? 386 TRP B CD1 1 
ATOM   6455 C  CD2 . TRP B 1 386 ? 128.927 132.896 97.011  1.00 82.35  ? 386 TRP B CD2 1 
ATOM   6456 N  NE1 . TRP B 1 386 ? 127.672 131.360 95.991  1.00 82.35  ? 386 TRP B NE1 1 
ATOM   6457 C  CE2 . TRP B 1 386 ? 127.698 132.227 97.048  1.00 82.35  ? 386 TRP B CE2 1 
ATOM   6458 C  CE3 . TRP B 1 386 ? 129.207 133.845 97.996  1.00 82.35  ? 386 TRP B CE3 1 
ATOM   6459 C  CZ2 . TRP B 1 386 ? 126.751 132.474 98.024  1.00 82.35  ? 386 TRP B CZ2 1 
ATOM   6460 C  CZ3 . TRP B 1 386 ? 128.270 134.087 98.960  1.00 82.35  ? 386 TRP B CZ3 1 
ATOM   6461 C  CH2 . TRP B 1 386 ? 127.055 133.405 98.971  1.00 82.35  ? 386 TRP B CH2 1 
ATOM   6462 N  N   . GLU B 1 387 ? 133.241 134.808 94.130  1.00 86.20  ? 387 GLU B N   1 
ATOM   6463 C  CA  . GLU B 1 387 ? 134.611 135.269 94.345  1.00 86.20  ? 387 GLU B CA  1 
ATOM   6464 C  C   . GLU B 1 387 ? 134.743 136.789 94.447  1.00 86.20  ? 387 GLU B C   1 
ATOM   6465 O  O   . GLU B 1 387 ? 135.438 137.248 95.368  1.00 86.20  ? 387 GLU B O   1 
ATOM   6466 C  CB  . GLU B 1 387 ? 135.538 134.673 93.282  1.00 86.20  ? 387 GLU B CB  1 
ATOM   6467 C  CG  . GLU B 1 387 ? 136.987 135.019 93.511  1.00 86.20  ? 387 GLU B CG  1 
ATOM   6468 C  CD  . GLU B 1 387 ? 137.889 134.517 92.412  1.00 86.20  ? 387 GLU B CD  1 
ATOM   6469 O  OE1 . GLU B 1 387 ? 138.626 135.338 91.829  1.00 86.20  ? 387 GLU B OE1 1 
ATOM   6470 O  OE2 . GLU B 1 387 ? 137.866 133.301 92.133  1.00 86.20  ? 387 GLU B OE2 1 
ATOM   6471 N  N   . PRO B 1 388 ? 134.123 137.628 93.591  1.00 84.98  ? 388 PRO B N   1 
ATOM   6472 C  CA  . PRO B 1 388 ? 134.210 139.071 93.868  1.00 84.98  ? 388 PRO B CA  1 
ATOM   6473 C  C   . PRO B 1 388 ? 133.367 139.519 95.046  1.00 84.98  ? 388 PRO B C   1 
ATOM   6474 O  O   . PRO B 1 388 ? 133.641 140.575 95.625  1.00 84.98  ? 388 PRO B O   1 
ATOM   6475 C  CB  . PRO B 1 388 ? 133.732 139.702 92.559  1.00 84.98  ? 388 PRO B CB  1 
ATOM   6476 C  CG  . PRO B 1 388 ? 132.852 138.716 91.995  1.00 84.98  ? 388 PRO B CG  1 
ATOM   6477 C  CD  . PRO B 1 388 ? 133.520 137.425 92.258  1.00 84.98  ? 388 PRO B CD  1 
ATOM   6478 N  N   . VAL B 1 389 ? 132.345 138.749 95.414  1.00 83.95  ? 389 VAL B N   1 
ATOM   6479 C  CA  . VAL B 1 389 ? 131.519 139.097 96.568  1.00 83.95  ? 389 VAL B CA  1 
ATOM   6480 C  C   . VAL B 1 389 ? 132.301 138.890 97.856  1.00 83.95  ? 389 VAL B C   1 
ATOM   6481 O  O   . VAL B 1 389 ? 132.345 139.767 98.726  1.00 83.95  ? 389 VAL B O   1 
ATOM   6482 C  CB  . VAL B 1 389 ? 130.217 138.276 96.554  1.00 83.95  ? 389 VAL B CB  1 
ATOM   6483 C  CG1 . VAL B 1 389 ? 129.541 138.302 97.906  1.00 83.95  ? 389 VAL B CG1 1 
ATOM   6484 C  CG2 . VAL B 1 389 ? 129.281 138.806 95.498  1.00 83.95  ? 389 VAL B CG2 1 
ATOM   6485 N  N   . LEU B 1 390 ? 132.948 137.731 97.986  1.00 82.30  ? 390 LEU B N   1 
ATOM   6486 C  CA  . LEU B 1 390 ? 133.716 137.431 99.188  1.00 82.30  ? 390 LEU B CA  1 
ATOM   6487 C  C   . LEU B 1 390 ? 134.990 138.254 99.261  1.00 82.30  ? 390 LEU B C   1 
ATOM   6488 O  O   . LEU B 1 390 ? 135.519 138.478 100.353 1.00 82.30  ? 390 LEU B O   1 
ATOM   6489 C  CB  . LEU B 1 390 ? 134.052 135.949 99.237  1.00 82.30  ? 390 LEU B CB  1 
ATOM   6490 C  CG  . LEU B 1 390 ? 132.872 135.044 99.538  1.00 82.30  ? 390 LEU B CG  1 
ATOM   6491 C  CD1 . LEU B 1 390 ? 133.258 133.625 99.264  1.00 82.30  ? 390 LEU B CD1 1 
ATOM   6492 C  CD2 . LEU B 1 390 ? 132.444 135.213 100.967 1.00 82.30  ? 390 LEU B CD2 1 
ATOM   6493 N  N   . LYS B 1 391 ? 135.505 138.700 98.119  1.00 84.39  ? 391 LYS B N   1 
ATOM   6494 C  CA  . LYS B 1 391 ? 136.672 139.570 98.138  1.00 84.39  ? 391 LYS B CA  1 
ATOM   6495 C  C   . LYS B 1 391 ? 136.316 140.948 98.671  1.00 84.39  ? 391 LYS B C   1 
ATOM   6496 O  O   . LYS B 1 391 ? 137.103 141.563 99.396  1.00 84.39  ? 391 LYS B O   1 
ATOM   6497 C  CB  . LYS B 1 391 ? 137.264 139.678 96.740  1.00 84.39  ? 391 LYS B CB  1 
ATOM   6498 C  CG  . LYS B 1 391 ? 138.608 140.340 96.709  1.00 84.39  ? 391 LYS B CG  1 
ATOM   6499 C  CD  . LYS B 1 391 ? 138.897 140.924 95.350  1.00 84.39  ? 391 LYS B CD  1 
ATOM   6500 C  CE  . LYS B 1 391 ? 140.374 141.200 95.196  1.00 84.39  ? 391 LYS B CE  1 
ATOM   6501 N  NZ  . LYS B 1 391 ? 140.991 141.594 96.490  1.00 84.39  ? 391 LYS B NZ  1 
ATOM   6502 N  N   . ALA B 1 392 ? 135.125 141.440 98.335  1.00 85.69  ? 392 ALA B N   1 
ATOM   6503 C  CA  . ALA B 1 392 ? 134.711 142.755 98.804  1.00 85.69  ? 392 ALA B CA  1 
ATOM   6504 C  C   . ALA B 1 392 ? 134.319 142.721 100.271 1.00 85.69  ? 392 ALA B C   1 
ATOM   6505 O  O   . ALA B 1 392 ? 134.496 143.710 100.985 1.00 85.69  ? 392 ALA B O   1 
ATOM   6506 C  CB  . ALA B 1 392 ? 133.554 143.272 97.960  1.00 85.69  ? 392 ALA B CB  1 
ATOM   6507 N  N   . LEU B 1 393 ? 133.771 141.598 100.735 1.00 83.78  ? 393 LEU B N   1 
ATOM   6508 C  CA  . LEU B 1 393 ? 133.433 141.470 102.149 1.00 83.78  ? 393 LEU B CA  1 
ATOM   6509 C  C   . LEU B 1 393 ? 134.683 141.410 103.009 1.00 83.78  ? 393 LEU B C   1 
ATOM   6510 O  O   . LEU B 1 393 ? 134.723 141.988 104.100 1.00 83.78  ? 393 LEU B O   1 
ATOM   6511 C  CB  . LEU B 1 393 ? 132.587 140.225 102.378 1.00 83.78  ? 393 LEU B CB  1 
ATOM   6512 C  CG  . LEU B 1 393 ? 131.143 140.286 101.909 1.00 83.78  ? 393 LEU B CG  1 
ATOM   6513 C  CD1 . LEU B 1 393 ? 130.458 138.969 102.184 1.00 83.78  ? 393 LEU B CD1 1 
ATOM   6514 C  CD2 . LEU B 1 393 ? 130.434 141.419 102.598 1.00 83.78  ? 393 LEU B CD2 1 
ATOM   6515 N  N   . LYS B 1 394 ? 135.710 140.710 102.531 1.00 85.58  ? 394 LYS B N   1 
ATOM   6516 C  CA  . LYS B 1 394 ? 136.960 140.590 103.264 1.00 85.58  ? 394 LYS B CA  1 
ATOM   6517 C  C   . LYS B 1 394 ? 137.699 141.914 103.344 1.00 85.58  ? 394 LYS B C   1 
ATOM   6518 O  O   . LYS B 1 394 ? 138.242 142.253 104.400 1.00 85.58  ? 394 LYS B O   1 
ATOM   6519 C  CB  . LYS B 1 394 ? 137.836 139.533 102.601 1.00 85.58  ? 394 LYS B CB  1 
ATOM   6520 C  CG  . LYS B 1 394 ? 139.199 139.350 103.220 1.00 85.58  ? 394 LYS B CG  1 
ATOM   6521 C  CD  . LYS B 1 394 ? 140.060 138.484 102.331 1.00 85.58  ? 394 LYS B CD  1 
ATOM   6522 C  CE  . LYS B 1 394 ? 141.495 138.479 102.789 1.00 85.58  ? 394 LYS B CE  1 
ATOM   6523 N  NZ  . LYS B 1 394 ? 141.626 137.802 104.099 1.00 85.58  ? 394 LYS B NZ  1 
ATOM   6524 N  N   . ASP B 1 395 ? 137.716 142.682 102.256 1.00 88.94  ? 395 ASP B N   1 
ATOM   6525 C  CA  . ASP B 1 395 ? 138.423 143.956 102.266 1.00 88.94  ? 395 ASP B CA  1 
ATOM   6526 C  C   . ASP B 1 395 ? 137.653 145.034 103.012 1.00 88.94  ? 395 ASP B C   1 
ATOM   6527 O  O   . ASP B 1 395 ? 138.256 145.989 103.509 1.00 88.94  ? 395 ASP B O   1 
ATOM   6528 C  CB  . ASP B 1 395 ? 138.711 144.415 100.840 1.00 88.94  ? 395 ASP B CB  1 
ATOM   6529 C  CG  . ASP B 1 395 ? 139.753 143.566 100.157 1.00 88.94  ? 395 ASP B CG  1 
ATOM   6530 O  OD1 . ASP B 1 395 ? 140.609 142.992 100.859 1.00 88.94  ? 395 ASP B OD1 1 
ATOM   6531 O  OD2 . ASP B 1 395 ? 139.724 143.478 98.915  1.00 88.94  ? 395 ASP B OD2 1 
ATOM   6532 N  N   . ALA B 1 396 ? 136.332 144.908 103.105 1.00 87.72  ? 396 ALA B N   1 
ATOM   6533 C  CA  . ALA B 1 396 ? 135.567 145.854 103.901 1.00 87.72  ? 396 ALA B CA  1 
ATOM   6534 C  C   . ALA B 1 396 ? 135.674 145.577 105.389 1.00 87.72  ? 396 ALA B C   1 
ATOM   6535 O  O   . ALA B 1 396 ? 135.221 146.399 106.189 1.00 87.72  ? 396 ALA B O   1 
ATOM   6536 C  CB  . ALA B 1 396 ? 134.100 145.841 103.483 1.00 87.72  ? 396 ALA B CB  1 
ATOM   6537 N  N   . GLY B 1 397 ? 136.250 144.448 105.775 1.00 83.77  ? 397 GLY B N   1 
ATOM   6538 C  CA  . GLY B 1 397 ? 136.470 144.138 107.165 1.00 83.77  ? 397 GLY B CA  1 
ATOM   6539 C  C   . GLY B 1 397 ? 135.397 143.309 107.820 1.00 83.77  ? 397 GLY B C   1 
ATOM   6540 O  O   . GLY B 1 397 ? 135.307 143.314 109.050 1.00 83.77  ? 397 GLY B O   1 
ATOM   6541 N  N   . TYR B 1 398 ? 134.576 142.607 107.048 1.00 79.09  ? 398 TYR B N   1 
ATOM   6542 C  CA  . TYR B 1 398 ? 133.538 141.780 107.639 1.00 79.09  ? 398 TYR B CA  1 
ATOM   6543 C  C   . TYR B 1 398 ? 134.151 140.525 108.232 1.00 79.09  ? 398 TYR B C   1 
ATOM   6544 O  O   . TYR B 1 398 ? 134.935 139.836 107.578 1.00 79.09  ? 398 TYR B O   1 
ATOM   6545 C  CB  . TYR B 1 398 ? 132.491 141.413 106.597 1.00 79.09  ? 398 TYR B CB  1 
ATOM   6546 C  CG  . TYR B 1 398 ? 131.317 140.669 107.171 1.00 79.09  ? 398 TYR B CG  1 
ATOM   6547 C  CD1 . TYR B 1 398 ? 130.397 141.311 107.981 1.00 79.09  ? 398 TYR B CD1 1 
ATOM   6548 C  CD2 . TYR B 1 398 ? 131.134 139.326 106.911 1.00 79.09  ? 398 TYR B CD2 1 
ATOM   6549 C  CE1 . TYR B 1 398 ? 129.328 140.636 108.510 1.00 79.09  ? 398 TYR B CE1 1 
ATOM   6550 C  CE2 . TYR B 1 398 ? 130.068 138.646 107.434 1.00 79.09  ? 398 TYR B CE2 1 
ATOM   6551 C  CZ  . TYR B 1 398 ? 129.171 139.306 108.231 1.00 79.09  ? 398 TYR B CZ  1 
ATOM   6552 O  OH  . TYR B 1 398 ? 128.106 138.625 108.754 1.00 79.09  ? 398 TYR B OH  1 
ATOM   6553 N  N   . THR B 1 399 ? 133.813 140.241 109.488 1.00 79.78  ? 399 THR B N   1 
ATOM   6554 C  CA  . THR B 1 399 ? 134.327 139.063 110.174 1.00 79.78  ? 399 THR B CA  1 
ATOM   6555 C  C   . THR B 1 399 ? 133.217 138.269 110.849 1.00 79.78  ? 399 THR B C   1 
ATOM   6556 O  O   . THR B 1 399 ? 133.499 137.473 111.747 1.00 79.78  ? 399 THR B O   1 
ATOM   6557 C  CB  . THR B 1 399 ? 135.375 139.445 111.218 1.00 79.78  ? 399 THR B CB  1 
ATOM   6558 O  OG1 . THR B 1 399 ? 134.889 140.538 112.001 1.00 79.78  ? 399 THR B OG1 1 
ATOM   6559 C  CG2 . THR B 1 399 ? 136.676 139.844 110.559 1.00 79.78  ? 399 THR B CG2 1 
ATOM   6560 N  N   . GLY B 1 400 ? 131.972 138.468 110.449 1.00 76.72  ? 400 GLY B N   1 
ATOM   6561 C  CA  . GLY B 1 400 ? 130.840 137.830 111.082 1.00 76.72  ? 400 GLY B CA  1 
ATOM   6562 C  C   . GLY B 1 400 ? 130.465 136.517 110.439 1.00 76.72  ? 400 GLY B C   1 
ATOM   6563 O  O   . GLY B 1 400 ? 131.301 135.789 109.904 1.00 76.72  ? 400 GLY B O   1 
ATOM   6564 N  N   . TYR B 1 401 ? 129.176 136.219 110.488 1.00 73.49  ? 401 TYR B N   1 
ATOM   6565 C  CA  . TYR B 1 401 ? 128.673 134.942 110.020 1.00 73.49  ? 401 TYR B CA  1 
ATOM   6566 C  C   . TYR B 1 401 ? 128.235 135.017 108.568 1.00 73.49  ? 401 TYR B C   1 
ATOM   6567 O  O   . TYR B 1 401 ? 127.826 136.066 108.074 1.00 73.49  ? 401 TYR B O   1 
ATOM   6568 C  CB  . TYR B 1 401 ? 127.494 134.493 110.871 1.00 73.49  ? 401 TYR B CB  1 
ATOM   6569 C  CG  . TYR B 1 401 ? 127.888 133.654 112.045 1.00 73.49  ? 401 TYR B CG  1 
ATOM   6570 C  CD1 . TYR B 1 401 ? 128.060 132.292 111.911 1.00 73.49  ? 401 TYR B CD1 1 
ATOM   6571 C  CD2 . TYR B 1 401 ? 128.092 134.226 113.286 1.00 73.49  ? 401 TYR B CD2 1 
ATOM   6572 C  CE1 . TYR B 1 401 ? 128.427 131.523 112.977 1.00 73.49  ? 401 TYR B CE1 1 
ATOM   6573 C  CE2 . TYR B 1 401 ? 128.458 133.464 114.358 1.00 73.49  ? 401 TYR B CE2 1 
ATOM   6574 C  CZ  . TYR B 1 401 ? 128.623 132.112 114.195 1.00 73.49  ? 401 TYR B CZ  1 
ATOM   6575 O  OH  . TYR B 1 401 ? 128.992 131.339 115.261 1.00 73.49  ? 401 TYR B OH  1 
ATOM   6576 N  N   . LEU B 1 402 ? 128.328 133.879 107.890 1.00 73.71  ? 402 LEU B N   1 
ATOM   6577 C  CA  . LEU B 1 402 ? 127.726 133.657 106.580 1.00 73.71  ? 402 LEU B CA  1 
ATOM   6578 C  C   . LEU B 1 402 ? 126.825 132.443 106.722 1.00 73.71  ? 402 LEU B C   1 
ATOM   6579 O  O   . LEU B 1 402 ? 127.299 131.309 106.664 1.00 73.71  ? 402 LEU B O   1 
ATOM   6580 C  CB  . LEU B 1 402 ? 128.778 133.422 105.503 1.00 73.71  ? 402 LEU B CB  1 
ATOM   6581 C  CG  . LEU B 1 402 ? 129.801 134.501 105.181 1.00 73.71  ? 402 LEU B CG  1 
ATOM   6582 C  CD1 . LEU B 1 402 ? 130.944 133.886 104.431 1.00 73.71  ? 402 LEU B CD1 1 
ATOM   6583 C  CD2 . LEU B 1 402 ? 129.176 135.573 104.354 1.00 73.71  ? 402 LEU B CD2 1 
ATOM   6584 N  N   . SER B 1 403 ? 125.535 132.669 106.919 1.00 75.48  ? 403 SER B N   1 
ATOM   6585 C  CA  . SER B 1 403 ? 124.593 131.573 107.068 1.00 75.48  ? 403 SER B CA  1 
ATOM   6586 C  C   . SER B 1 403 ? 124.061 131.147 105.715 1.00 75.48  ? 403 SER B C   1 
ATOM   6587 O  O   . SER B 1 403 ? 123.633 131.983 104.920 1.00 75.48  ? 403 SER B O   1 
ATOM   6588 C  CB  . SER B 1 403 ? 123.440 131.956 107.984 1.00 75.48  ? 403 SER B CB  1 
ATOM   6589 O  OG  . SER B 1 403 ? 123.798 131.767 109.335 1.00 75.48  ? 403 SER B OG  1 
ATOM   6590 N  N   . SER B 1 404 ? 124.081 129.844 105.467 1.00 75.45  ? 404 SER B N   1 
ATOM   6591 C  CA  . SER B 1 404 ? 123.613 129.304 104.203 1.00 75.45  ? 404 SER B CA  1 
ATOM   6592 C  C   . SER B 1 404 ? 122.103 129.407 104.101 1.00 75.45  ? 404 SER B C   1 
ATOM   6593 O  O   . SER B 1 404 ? 121.385 129.010 105.018 1.00 75.45  ? 404 SER B O   1 
ATOM   6594 C  CB  . SER B 1 404 ? 124.033 127.847 104.079 1.00 75.45  ? 404 SER B CB  1 
ATOM   6595 O  OG  . SER B 1 404 ? 125.370 127.748 103.643 1.00 75.45  ? 404 SER B OG  1 
ATOM   6596 N  N   . GLU B 1 405 ? 121.616 129.926 102.980 1.00 80.59  ? 405 GLU B N   1 
ATOM   6597 C  CA  . GLU B 1 405 ? 120.187 129.929 102.675 1.00 80.59  ? 405 GLU B CA  1 
ATOM   6598 C  C   . GLU B 1 405 ? 120.003 129.321 101.295 1.00 80.59  ? 405 GLU B C   1 
ATOM   6599 O  O   . GLU B 1 405 ? 120.224 129.975 100.279 1.00 80.59  ? 405 GLU B O   1 
ATOM   6600 C  CB  . GLU B 1 405 ? 119.601 131.309 102.757 1.00 80.59  ? 405 GLU B CB  1 
ATOM   6601 C  CG  . GLU B 1 405 ? 119.217 131.697 104.149 1.00 80.59  ? 405 GLU B CG  1 
ATOM   6602 C  CD  . GLU B 1 405 ? 118.039 132.634 104.186 1.00 80.59  ? 405 GLU B CD  1 
ATOM   6603 O  OE1 . GLU B 1 405 ? 117.672 133.180 103.126 1.00 80.59  ? 405 GLU B OE1 1 
ATOM   6604 O  OE2 . GLU B 1 405 ? 117.465 132.815 105.279 1.00 80.59  ? 405 GLU B OE2 1 
ATOM   6605 N  N   . TYR B 1 406 ? 119.591 128.063 101.262 1.00 75.65  ? 406 TYR B N   1 
ATOM   6606 C  CA  . TYR B 1 406 ? 119.346 127.400 99.995  1.00 75.65  ? 406 TYR B CA  1 
ATOM   6607 C  C   . TYR B 1 406 ? 117.951 127.734 99.495  1.00 75.65  ? 406 TYR B C   1 
ATOM   6608 O  O   . TYR B 1 406 ? 116.966 127.596 100.222 1.00 75.65  ? 406 TYR B O   1 
ATOM   6609 C  CB  . TYR B 1 406 ? 119.517 125.897 100.159 1.00 75.65  ? 406 TYR B CB  1 
ATOM   6610 C  CG  . TYR B 1 406 ? 119.187 125.097 98.934  1.00 75.65  ? 406 TYR B CG  1 
ATOM   6611 C  CD1 . TYR B 1 406 ? 119.916 125.243 97.772  1.00 75.65  ? 406 TYR B CD1 1 
ATOM   6612 C  CD2 . TYR B 1 406 ? 118.150 124.185 98.944  1.00 75.65  ? 406 TYR B CD2 1 
ATOM   6613 C  CE1 . TYR B 1 406 ? 119.617 124.512 96.657  1.00 75.65  ? 406 TYR B CE1 1 
ATOM   6614 C  CE2 . TYR B 1 406 ? 117.846 123.447 97.834  1.00 75.65  ? 406 TYR B CE2 1 
ATOM   6615 C  CZ  . TYR B 1 406 ? 118.585 123.614 96.697  1.00 75.65  ? 406 TYR B CZ  1 
ATOM   6616 O  OH  . TYR B 1 406 ? 118.283 122.880 95.586  1.00 75.65  ? 406 TYR B OH  1 
ATOM   6617 N  N   . GLU B 1 407 ? 117.868 128.162 98.243  1.00 80.05  ? 407 GLU B N   1 
ATOM   6618 C  CA  . GLU B 1 407 ? 116.647 128.692 97.655  1.00 80.05  ? 407 GLU B CA  1 
ATOM   6619 C  C   . GLU B 1 407 ? 116.277 127.900 96.408  1.00 80.05  ? 407 GLU B C   1 
ATOM   6620 O  O   . GLU B 1 407 ? 115.325 128.230 95.699  1.00 80.05  ? 407 GLU B O   1 
ATOM   6621 C  CB  . GLU B 1 407 ? 116.836 130.175 97.337  1.00 80.05  ? 407 GLU B CB  1 
ATOM   6622 C  CG  . GLU B 1 407 ? 115.595 131.025 97.090  1.00 80.05  ? 407 GLU B CG  1 
ATOM   6623 C  CD  . GLU B 1 407 ? 114.806 131.285 98.331  1.00 80.05  ? 407 GLU B CD  1 
ATOM   6624 O  OE1 . GLU B 1 407 ? 115.433 131.516 99.378  1.00 80.05  ? 407 GLU B OE1 1 
ATOM   6625 O  OE2 . GLU B 1 407 ? 113.562 131.262 98.261  1.00 80.05  ? 407 GLU B OE2 1 
ATOM   6626 N  N   . GLY B 1 408 ? 117.002 126.824 96.132  1.00 79.43  ? 408 GLY B N   1 
ATOM   6627 C  CA  . GLY B 1 408 ? 116.838 126.081 94.903  1.00 79.43  ? 408 GLY B CA  1 
ATOM   6628 C  C   . GLY B 1 408 ? 115.593 125.218 94.888  1.00 79.43  ? 408 GLY B C   1 
ATOM   6629 O  O   . GLY B 1 408 ? 114.619 125.454 95.602  1.00 79.43  ? 408 GLY B O   1 
ATOM   6630 N  N   . GLU B 1 409 ? 115.633 124.199 94.039  1.00 82.40  ? 409 GLU B N   1 
ATOM   6631 C  CA  . GLU B 1 409 ? 114.500 123.298 93.914  1.00 82.40  ? 409 GLU B CA  1 
ATOM   6632 C  C   . GLU B 1 409 ? 114.378 122.437 95.157  1.00 82.40  ? 409 GLU B C   1 
ATOM   6633 O  O   . GLU B 1 409 ? 115.369 121.908 95.661  1.00 82.40  ? 409 GLU B O   1 
ATOM   6634 C  CB  . GLU B 1 409 ? 114.656 122.416 92.677  1.00 82.40  ? 409 GLU B CB  1 
ATOM   6635 C  CG  . GLU B 1 409 ? 114.868 123.147 91.343  1.00 82.40  ? 409 GLU B CG  1 
ATOM   6636 C  CD  . GLU B 1 409 ? 113.624 123.814 90.736  1.00 82.40  ? 409 GLU B CD  1 
ATOM   6637 O  OE1 . GLU B 1 409 ? 112.812 124.443 91.447  1.00 82.40  ? 409 GLU B OE1 1 
ATOM   6638 O  OE2 . GLU B 1 409 ? 113.465 123.711 89.502  1.00 82.40  ? 409 GLU B OE2 1 
ATOM   6639 N  N   . ARG B 1 410 ? 113.155 122.295 95.651  1.00 79.37  ? 410 ARG B N   1 
ATOM   6640 C  CA  . ARG B 1 410 ? 112.904 121.510 96.855  1.00 79.37  ? 410 ARG B CA  1 
ATOM   6641 C  C   . ARG B 1 410 ? 112.657 120.044 96.512  1.00 79.37  ? 410 ARG B C   1 
ATOM   6642 O  O   . ARG B 1 410 ? 111.649 119.451 96.878  1.00 79.37  ? 410 ARG B O   1 
ATOM   6643 C  CB  . ARG B 1 410 ? 111.736 122.098 97.630  1.00 79.37  ? 410 ARG B CB  1 
ATOM   6644 C  CG  . ARG B 1 410 ? 111.863 123.571 97.901  1.00 79.37  ? 410 ARG B CG  1 
ATOM   6645 C  CD  . ARG B 1 410 ? 113.053 123.858 98.767  1.00 79.37  ? 410 ARG B CD  1 
ATOM   6646 N  NE  . ARG B 1 410 ? 113.105 125.258 99.154  1.00 79.37  ? 410 ARG B NE  1 
ATOM   6647 C  CZ  . ARG B 1 410 ? 114.093 125.796 99.851  1.00 79.37  ? 410 ARG B CZ  1 
ATOM   6648 N  NH1 . ARG B 1 410 ? 115.107 125.046 100.242 1.00 79.37  ? 410 ARG B NH1 1 
ATOM   6649 N  NH2 . ARG B 1 410 ? 114.062 127.077 100.166 1.00 79.37  ? 410 ARG B NH2 1 
ATOM   6650 N  N   . GLU B 1 411 ? 113.588 119.474 95.775  1.00 82.65  ? 411 GLU B N   1 
ATOM   6651 C  CA  . GLU B 1 411 ? 113.667 118.037 95.628  1.00 82.65  ? 411 GLU B CA  1 
ATOM   6652 C  C   . GLU B 1 411 ? 114.056 117.429 96.973  1.00 82.65  ? 411 GLU B C   1 
ATOM   6653 O  O   . GLU B 1 411 ? 114.826 118.039 97.717  1.00 82.65  ? 411 GLU B O   1 
ATOM   6654 C  CB  . GLU B 1 411 ? 114.701 117.693 94.561  1.00 82.65  ? 411 GLU B CB  1 
ATOM   6655 C  CG  . GLU B 1 411 ? 114.723 116.266 94.074  1.00 82.65  ? 411 GLU B CG  1 
ATOM   6656 C  CD  . GLU B 1 411 ? 115.996 115.943 93.320  1.00 82.65  ? 411 GLU B CD  1 
ATOM   6657 O  OE1 . GLU B 1 411 ? 116.461 116.802 92.542  1.00 82.65  ? 411 GLU B OE1 1 
ATOM   6658 O  OE2 . GLU B 1 411 ? 116.537 114.835 93.504  1.00 82.65  ? 411 GLU B OE2 1 
ATOM   6659 N  N   . PRO B 1 412 ? 113.501 116.273 97.336  1.00 77.20  ? 412 PRO B N   1 
ATOM   6660 C  CA  . PRO B 1 412 ? 113.819 115.679 98.641  1.00 77.20  ? 412 PRO B CA  1 
ATOM   6661 C  C   . PRO B 1 412 ? 115.278 115.259 98.749  1.00 77.20  ? 412 PRO B C   1 
ATOM   6662 O  O   . PRO B 1 412 ? 115.833 114.641 97.841  1.00 77.20  ? 412 PRO B O   1 
ATOM   6663 C  CB  . PRO B 1 412 ? 112.876 114.477 98.712  1.00 77.20  ? 412 PRO B CB  1 
ATOM   6664 C  CG  . PRO B 1 412 ? 111.758 114.833 97.845  1.00 77.20  ? 412 PRO B CG  1 
ATOM   6665 C  CD  . PRO B 1 412 ? 112.326 115.632 96.728  1.00 77.20  ? 412 PRO B CD  1 
ATOM   6666 N  N   . TRP B 1 413 ? 115.898 115.639 99.868  1.00 73.74  ? 413 TRP B N   1 
ATOM   6667 C  CA  . TRP B 1 413 ? 117.301 115.483 100.270 1.00 73.74  ? 413 TRP B CA  1 
ATOM   6668 C  C   . TRP B 1 413 ? 118.269 116.250 99.385  1.00 73.74  ? 413 TRP B C   1 
ATOM   6669 O  O   . TRP B 1 413 ? 119.472 116.063 99.534  1.00 73.74  ? 413 TRP B O   1 
ATOM   6670 C  CB  . TRP B 1 413 ? 117.773 114.023 100.327 1.00 73.74  ? 413 TRP B CB  1 
ATOM   6671 C  CG  . TRP B 1 413 ? 117.079 113.242 101.352 1.00 73.74  ? 413 TRP B CG  1 
ATOM   6672 C  CD1 . TRP B 1 413 ? 117.388 113.163 102.666 1.00 73.74  ? 413 TRP B CD1 1 
ATOM   6673 C  CD2 . TRP B 1 413 ? 115.933 112.432 101.158 1.00 73.74  ? 413 TRP B CD2 1 
ATOM   6674 N  NE1 . TRP B 1 413 ? 116.506 112.345 103.310 1.00 73.74  ? 413 TRP B NE1 1 
ATOM   6675 C  CE2 . TRP B 1 413 ? 115.598 111.882 102.399 1.00 73.74  ? 413 TRP B CE2 1 
ATOM   6676 C  CE3 . TRP B 1 413 ? 115.158 112.109 100.048 1.00 73.74  ? 413 TRP B CE3 1 
ATOM   6677 C  CZ2 . TRP B 1 413 ? 114.526 111.033 102.562 1.00 73.74  ? 413 TRP B CZ2 1 
ATOM   6678 C  CZ3 . TRP B 1 413 ? 114.091 111.287 100.213 1.00 73.74  ? 413 TRP B CZ3 1 
ATOM   6679 C  CH2 . TRP B 1 413 ? 113.775 110.763 101.460 1.00 73.74  ? 413 TRP B CH2 1 
ATOM   6680 N  N   . ARG B 1 414 ? 117.797 117.103 98.481  1.00 74.97  ? 414 ARG B N   1 
ATOM   6681 C  CA  . ARG B 1 414 ? 118.713 117.846 97.630  1.00 74.97  ? 414 ARG B CA  1 
ATOM   6682 C  C   . ARG B 1 414 ? 119.413 118.942 98.416  1.00 74.97  ? 414 ARG B C   1 
ATOM   6683 O  O   . ARG B 1 414 ? 120.567 119.276 98.136  1.00 74.97  ? 414 ARG B O   1 
ATOM   6684 C  CB  . ARG B 1 414 ? 117.957 118.426 96.439  1.00 74.97  ? 414 ARG B CB  1 
ATOM   6685 C  CG  . ARG B 1 414 ? 118.848 119.053 95.407  1.00 74.97  ? 414 ARG B CG  1 
ATOM   6686 C  CD  . ARG B 1 414 ? 118.079 119.655 94.268  1.00 74.97  ? 414 ARG B CD  1 
ATOM   6687 N  NE  . ARG B 1 414 ? 118.769 120.817 93.726  1.00 74.97  ? 414 ARG B NE  1 
ATOM   6688 C  CZ  . ARG B 1 414 ? 119.753 120.759 92.838  1.00 74.97  ? 414 ARG B CZ  1 
ATOM   6689 N  NH1 . ARG B 1 414 ? 120.172 119.594 92.379  1.00 74.97  ? 414 ARG B NH1 1 
ATOM   6690 N  NH2 . ARG B 1 414 ? 120.321 121.872 92.409  1.00 74.97  ? 414 ARG B NH2 1 
ATOM   6691 N  N   . SER B 1 415 ? 118.745 119.475 99.436  1.00 74.58  ? 415 SER B N   1 
ATOM   6692 C  CA  . SER B 1 415 ? 119.274 120.615 100.170 1.00 74.58  ? 415 SER B CA  1 
ATOM   6693 C  C   . SER B 1 415 ? 120.440 120.236 101.065 1.00 74.58  ? 415 SER B C   1 
ATOM   6694 O  O   . SER B 1 415 ? 121.223 121.104 101.453 1.00 74.58  ? 415 SER B O   1 
ATOM   6695 C  CB  . SER B 1 415 ? 118.169 121.241 101.005 1.00 74.58  ? 415 SER B CB  1 
ATOM   6696 O  OG  . SER B 1 415 ? 117.576 120.275 101.844 1.00 74.58  ? 415 SER B OG  1 
ATOM   6697 N  N   . ILE B 1 416 ? 120.566 118.959 101.419 1.00 73.27  ? 416 ILE B N   1 
ATOM   6698 C  CA  . ILE B 1 416 ? 121.677 118.526 102.259 1.00 73.27  ? 416 ILE B CA  1 
ATOM   6699 C  C   . ILE B 1 416 ? 122.983 118.618 101.488 1.00 73.27  ? 416 ILE B C   1 
ATOM   6700 O  O   . ILE B 1 416 ? 123.989 119.125 101.991 1.00 73.27  ? 416 ILE B O   1 
ATOM   6701 C  CB  . ILE B 1 416 ? 121.430 117.101 102.778 1.00 73.27  ? 416 ILE B CB  1 
ATOM   6702 C  CG1 . ILE B 1 416 ? 120.129 117.045 103.564 1.00 73.27  ? 416 ILE B CG1 1 
ATOM   6703 C  CG2 . ILE B 1 416 ? 122.571 116.646 103.648 1.00 73.27  ? 416 ILE B CG2 1 
ATOM   6704 C  CD1 . ILE B 1 416 ? 119.708 115.654 103.908 1.00 73.27  ? 416 ILE B CD1 1 
ATOM   6705 N  N   . GLU B 1 417 ? 122.974 118.158 100.242 1.00 73.05  ? 417 GLU B N   1 
ATOM   6706 C  CA  . GLU B 1 417 ? 124.184 118.175 99.436  1.00 73.05  ? 417 GLU B CA  1 
ATOM   6707 C  C   . GLU B 1 417 ? 124.512 119.582 98.962  1.00 73.05  ? 417 GLU B C   1 
ATOM   6708 O  O   . GLU B 1 417 ? 125.683 119.918 98.769  1.00 73.05  ? 417 GLU B O   1 
ATOM   6709 C  CB  . GLU B 1 417 ? 124.015 117.221 98.257  1.00 73.05  ? 417 GLU B CB  1 
ATOM   6710 C  CG  . GLU B 1 417 ? 125.247 117.015 97.407  1.00 73.05  ? 417 GLU B CG  1 
ATOM   6711 C  CD  . GLU B 1 417 ? 126.379 116.375 98.166  1.00 73.05  ? 417 GLU B CD  1 
ATOM   6712 O  OE1 . GLU B 1 417 ? 126.121 115.485 98.995  1.00 73.05  ? 417 GLU B OE1 1 
ATOM   6713 O  OE2 . GLU B 1 417 ? 127.534 116.768 97.937  1.00 73.05  ? 417 GLU B OE2 1 
ATOM   6714 N  N   . GLN B 1 418 ? 123.498 120.429 98.802  1.00 73.79  ? 418 GLN B N   1 
ATOM   6715 C  CA  . GLN B 1 418 ? 123.729 121.760 98.256  1.00 73.79  ? 418 GLN B CA  1 
ATOM   6716 C  C   . GLN B 1 418 ? 124.381 122.678 99.279  1.00 73.79  ? 418 GLN B C   1 
ATOM   6717 O  O   . GLN B 1 418 ? 125.218 123.513 98.930  1.00 73.79  ? 418 GLN B O   1 
ATOM   6718 C  CB  . GLN B 1 418 ? 122.417 122.352 97.759  1.00 73.79  ? 418 GLN B CB  1 
ATOM   6719 C  CG  . GLN B 1 418 ? 121.933 121.745 96.472  1.00 73.79  ? 418 GLN B CG  1 
ATOM   6720 C  CD  . GLN B 1 418 ? 122.845 122.041 95.317  1.00 73.79  ? 418 GLN B CD  1 
ATOM   6721 O  OE1 . GLN B 1 418 ? 123.090 123.192 94.990  1.00 73.79  ? 418 GLN B OE1 1 
ATOM   6722 N  NE2 . GLN B 1 418 ? 123.352 121.000 94.686  1.00 73.79  ? 418 GLN B NE2 1 
ATOM   6723 N  N   . VAL B 1 419 ? 124.011 122.538 100.550 1.00 71.70  ? 419 VAL B N   1 
ATOM   6724 C  CA  . VAL B 1 419 ? 124.620 123.353 101.595 1.00 71.70  ? 419 VAL B CA  1 
ATOM   6725 C  C   . VAL B 1 419 ? 126.059 122.912 101.838 1.00 71.70  ? 419 VAL B C   1 
ATOM   6726 O  O   . VAL B 1 419 ? 126.934 123.735 102.128 1.00 71.70  ? 419 VAL B O   1 
ATOM   6727 C  CB  . VAL B 1 419 ? 123.751 123.296 102.868 1.00 71.70  ? 419 VAL B CB  1 
ATOM   6728 C  CG1 . VAL B 1 419 ? 124.393 123.994 104.033 1.00 71.70  ? 419 VAL B CG1 1 
ATOM   6729 C  CG2 . VAL B 1 419 ? 122.424 123.940 102.600 1.00 71.70  ? 419 VAL B CG2 1 
ATOM   6730 N  N   . ARG B 1 420 ? 126.338 121.617 101.668 1.00 70.28  ? 420 ARG B N   1 
ATOM   6731 C  CA  . ARG B 1 420 ? 127.708 121.124 101.760 1.00 70.28  ? 420 ARG B CA  1 
ATOM   6732 C  C   . ARG B 1 420 ? 128.575 121.683 100.647 1.00 70.28  ? 420 ARG B C   1 
ATOM   6733 O  O   . ARG B 1 420 ? 129.760 121.955 100.851 1.00 70.28  ? 420 ARG B O   1 
ATOM   6734 C  CB  . ARG B 1 420 ? 127.730 119.603 101.704 1.00 70.28  ? 420 ARG B CB  1 
ATOM   6735 C  CG  . ARG B 1 420 ? 127.192 118.930 102.916 1.00 70.28  ? 420 ARG B CG  1 
ATOM   6736 C  CD  . ARG B 1 420 ? 127.374 117.441 102.839 1.00 70.28  ? 420 ARG B CD  1 
ATOM   6737 N  NE  . ARG B 1 420 ? 128.741 117.023 103.119 1.00 70.28  ? 420 ARG B NE  1 
ATOM   6738 C  CZ  . ARG B 1 420 ? 129.225 116.819 104.337 1.00 70.28  ? 420 ARG B CZ  1 
ATOM   6739 N  NH1 . ARG B 1 420 ? 128.461 117.002 105.397 1.00 70.28  ? 420 ARG B NH1 1 
ATOM   6740 N  NH2 . ARG B 1 420 ? 130.475 116.430 104.494 1.00 70.28  ? 420 ARG B NH2 1 
ATOM   6741 N  N   . ARG B 1 421 ? 127.997 121.865 99.463  1.00 72.92  ? 421 ARG B N   1 
ATOM   6742 C  CA  . ARG B 1 421 ? 128.763 122.382 98.341  1.00 72.92  ? 421 ARG B CA  1 
ATOM   6743 C  C   . ARG B 1 421 ? 129.048 123.861 98.506  1.00 72.92  ? 421 ARG B C   1 
ATOM   6744 O  O   . ARG B 1 421 ? 130.049 124.365 97.993  1.00 72.92  ? 421 ARG B O   1 
ATOM   6745 C  CB  . ARG B 1 421 ? 128.014 122.126 97.042  1.00 72.92  ? 421 ARG B CB  1 
ATOM   6746 C  CG  . ARG B 1 421 ? 128.099 120.709 96.598  1.00 72.92  ? 421 ARG B CG  1 
ATOM   6747 C  CD  . ARG B 1 421 ? 127.284 120.452 95.379  1.00 72.92  ? 421 ARG B CD  1 
ATOM   6748 N  NE  . ARG B 1 421 ? 127.185 119.025 95.143  1.00 72.92  ? 421 ARG B NE  1 
ATOM   6749 C  CZ  . ARG B 1 421 ? 126.517 118.481 94.141  1.00 72.92  ? 421 ARG B CZ  1 
ATOM   6750 N  NH1 . ARG B 1 421 ? 125.884 119.250 93.274  1.00 72.92  ? 421 ARG B NH1 1 
ATOM   6751 N  NH2 . ARG B 1 421 ? 126.482 117.168 94.010  1.00 72.92  ? 421 ARG B NH2 1 
ATOM   6752 N  N   . GLN B 1 422 ? 128.188 124.574 99.227  1.00 74.42  ? 422 GLN B N   1 
ATOM   6753 C  CA  . GLN B 1 422 ? 128.389 126.005 99.385  1.00 74.42  ? 422 GLN B CA  1 
ATOM   6754 C  C   . GLN B 1 422 ? 129.462 126.302 100.416 1.00 74.42  ? 422 GLN B C   1 
ATOM   6755 O  O   . GLN B 1 422 ? 130.259 127.226 100.241 1.00 74.42  ? 422 GLN B O   1 
ATOM   6756 C  CB  . GLN B 1 422 ? 127.091 126.684 99.778  1.00 74.42  ? 422 GLN B CB  1 
ATOM   6757 C  CG  . GLN B 1 422 ? 127.106 128.149 99.481  1.00 74.42  ? 422 GLN B CG  1 
ATOM   6758 C  CD  . GLN B 1 422 ? 126.246 128.919 100.422 1.00 74.42  ? 422 GLN B CD  1 
ATOM   6759 O  OE1 . GLN B 1 422 ? 126.005 128.491 101.539 1.00 74.42  ? 422 GLN B OE1 1 
ATOM   6760 N  NE2 . GLN B 1 422 ? 125.758 130.055 99.976  1.00 74.42  ? 422 GLN B NE2 1 
ATOM   6761 N  N   . HIS B 1 423 ? 129.484 125.544 101.508 1.00 73.38  ? 423 HIS B N   1 
ATOM   6762 C  CA  . HIS B 1 423 ? 130.521 125.731 102.511 1.00 73.38  ? 423 HIS B CA  1 
ATOM   6763 C  C   . HIS B 1 423 ? 131.870 125.276 101.989 1.00 73.38  ? 423 HIS B C   1 
ATOM   6764 O  O   . HIS B 1 423 ? 132.904 125.839 102.350 1.00 73.38  ? 423 HIS B O   1 
ATOM   6765 C  CB  . HIS B 1 423 ? 130.158 124.978 103.782 1.00 73.38  ? 423 HIS B CB  1 
ATOM   6766 C  CG  . HIS B 1 423 ? 129.222 125.725 104.673 1.00 73.38  ? 423 HIS B CG  1 
ATOM   6767 N  ND1 . HIS B 1 423 ? 129.612 126.250 105.883 1.00 73.38  ? 423 HIS B ND1 1 
ATOM   6768 C  CD2 . HIS B 1 423 ? 127.917 126.043 104.528 1.00 73.38  ? 423 HIS B CD2 1 
ATOM   6769 C  CE1 . HIS B 1 423 ? 128.585 126.857 106.446 1.00 73.38  ? 423 HIS B CE1 1 
ATOM   6770 N  NE2 . HIS B 1 423 ? 127.545 126.747 105.643 1.00 73.38  ? 423 HIS B NE2 1 
ATOM   6771 N  N   . SER B 1 424 ? 131.877 124.261 101.131 1.00 74.80  ? 424 SER B N   1 
ATOM   6772 C  CA  . SER B 1 424 ? 133.117 123.834 100.503 1.00 74.80  ? 424 SER B CA  1 
ATOM   6773 C  C   . SER B 1 424 ? 133.607 124.866 99.502  1.00 74.80  ? 424 SER B C   1 
ATOM   6774 O  O   . SER B 1 424 ? 134.813 125.057 99.338  1.00 74.80  ? 424 SER B O   1 
ATOM   6775 C  CB  . SER B 1 424 ? 132.918 122.487 99.824  1.00 74.80  ? 424 SER B CB  1 
ATOM   6776 O  OG  . SER B 1 424 ? 134.156 121.942 99.428  1.00 74.80  ? 424 SER B OG  1 
ATOM   6777 N  N   . LEU B 1 425 ? 132.686 125.548 98.827  1.00 75.97  ? 425 LEU B N   1 
ATOM   6778 C  CA  . LEU B 1 425 ? 133.081 126.528 97.824  1.00 75.97  ? 425 LEU B CA  1 
ATOM   6779 C  C   . LEU B 1 425 ? 133.552 127.822 98.470  1.00 75.97  ? 425 LEU B C   1 
ATOM   6780 O  O   . LEU B 1 425 ? 134.538 128.420 98.031  1.00 75.97  ? 425 LEU B O   1 
ATOM   6781 C  CB  . LEU B 1 425 ? 131.921 126.798 96.871  1.00 75.97  ? 425 LEU B CB  1 
ATOM   6782 C  CG  . LEU B 1 425 ? 132.039 127.980 95.913  1.00 75.97  ? 425 LEU B CG  1 
ATOM   6783 C  CD1 . LEU B 1 425 ? 133.145 127.740 94.923  1.00 75.97  ? 425 LEU B CD1 1 
ATOM   6784 C  CD2 . LEU B 1 425 ? 130.735 128.205 95.202  1.00 75.97  ? 425 LEU B CD2 1 
ATOM   6785 N  N   . ILE B 1 426 ? 132.860 128.269 99.517  1.00 75.94  ? 426 ILE B N   1 
ATOM   6786 C  CA  . ILE B 1 426 ? 133.171 129.558 100.123 1.00 75.94  ? 426 ILE B CA  1 
ATOM   6787 C  C   . ILE B 1 426 ? 134.472 129.486 100.911 1.00 75.94  ? 426 ILE B C   1 
ATOM   6788 O  O   . ILE B 1 426 ? 135.308 130.392 100.833 1.00 75.94  ? 426 ILE B O   1 
ATOM   6789 C  CB  . ILE B 1 426 ? 131.988 130.020 100.991 1.00 75.94  ? 426 ILE B CB  1 
ATOM   6790 C  CG1 . ILE B 1 426 ? 130.848 130.494 100.102 1.00 75.94  ? 426 ILE B CG1 1 
ATOM   6791 C  CG2 . ILE B 1 426 ? 132.374 131.141 101.916 1.00 75.94  ? 426 ILE B CG2 1 
ATOM   6792 C  CD1 . ILE B 1 426 ? 129.602 130.812 100.862 1.00 75.94  ? 426 ILE B CD1 1 
ATOM   6793 N  N   . ARG B 1 427 ? 134.685 128.392 101.645 1.00 77.39  ? 427 ARG B N   1 
ATOM   6794 C  CA  . ARG B 1 427 ? 135.909 128.246 102.426 1.00 77.39  ? 427 ARG B CA  1 
ATOM   6795 C  C   . ARG B 1 427 ? 137.125 128.065 101.530 1.00 77.39  ? 427 ARG B C   1 
ATOM   6796 O  O   . ARG B 1 427 ? 138.243 128.420 101.913 1.00 77.39  ? 427 ARG B O   1 
ATOM   6797 C  CB  . ARG B 1 427 ? 135.783 127.066 103.381 1.00 77.39  ? 427 ARG B CB  1 
ATOM   6798 C  CG  . ARG B 1 427 ? 134.930 127.328 104.589 1.00 77.39  ? 427 ARG B CG  1 
ATOM   6799 C  CD  . ARG B 1 427 ? 134.510 126.030 105.217 1.00 77.39  ? 427 ARG B CD  1 
ATOM   6800 N  NE  . ARG B 1 427 ? 134.129 126.177 106.610 1.00 77.39  ? 427 ARG B NE  1 
ATOM   6801 C  CZ  . ARG B 1 427 ? 134.965 126.012 107.623 1.00 77.39  ? 427 ARG B CZ  1 
ATOM   6802 N  NH1 . ARG B 1 427 ? 136.228 125.700 107.390 1.00 77.39  ? 427 ARG B NH1 1 
ATOM   6803 N  NH2 . ARG B 1 427 ? 134.542 126.166 108.865 1.00 77.39  ? 427 ARG B NH2 1 
ATOM   6804 N  N   . GLN B 1 428 ? 136.931 127.518 100.335 1.00 79.85  ? 428 GLN B N   1 
ATOM   6805 C  CA  . GLN B 1 428 ? 138.049 127.381 99.413  1.00 79.85  ? 428 GLN B CA  1 
ATOM   6806 C  C   . GLN B 1 428 ? 138.383 128.706 98.754  1.00 79.85  ? 428 GLN B C   1 
ATOM   6807 O  O   . GLN B 1 428 ? 139.542 128.959 98.415  1.00 79.85  ? 428 GLN B O   1 
ATOM   6808 C  CB  . GLN B 1 428 ? 137.734 126.330 98.361  1.00 79.85  ? 428 GLN B CB  1 
ATOM   6809 C  CG  . GLN B 1 428 ? 138.047 124.933 98.802  1.00 79.85  ? 428 GLN B CG  1 
ATOM   6810 C  CD  . GLN B 1 428 ? 137.776 123.927 97.722  1.00 79.85  ? 428 GLN B CD  1 
ATOM   6811 O  OE1 . GLN B 1 428 ? 136.725 123.296 97.696  1.00 79.85  ? 428 GLN B OE1 1 
ATOM   6812 N  NE2 . GLN B 1 428 ? 138.728 123.766 96.819  1.00 79.85  ? 428 GLN B NE2 1 
ATOM   6813 N  N   . ILE B 1 429 ? 137.380 129.558 98.550  1.00 80.53  ? 429 ILE B N   1 
ATOM   6814 C  CA  . ILE B 1 429 ? 137.628 130.880 97.990  1.00 80.53  ? 429 ILE B CA  1 
ATOM   6815 C  C   . ILE B 1 429 ? 138.326 131.762 99.014  1.00 80.53  ? 429 ILE B C   1 
ATOM   6816 O  O   . ILE B 1 429 ? 139.276 132.483 98.690  1.00 80.53  ? 429 ILE B O   1 
ATOM   6817 C  CB  . ILE B 1 429 ? 136.306 131.495 97.497  1.00 80.53  ? 429 ILE B CB  1 
ATOM   6818 C  CG1 . ILE B 1 429 ? 135.868 130.824 96.206  1.00 80.53  ? 429 ILE B CG1 1 
ATOM   6819 C  CG2 . ILE B 1 429 ? 136.433 132.974 97.250  1.00 80.53  ? 429 ILE B CG2 1 
ATOM   6820 C  CD1 . ILE B 1 429 ? 134.502 131.224 95.765  1.00 80.53  ? 429 ILE B CD1 1 
ATOM   6821 N  N   . ALA B 1 430 ? 137.914 131.666 100.279 1.00 82.20  ? 430 ALA B N   1 
ATOM   6822 C  CA  . ALA B 1 430 ? 138.469 132.525 101.318 1.00 82.20  ? 430 ALA B CA  1 
ATOM   6823 C  C   . ALA B 1 430 ? 139.904 132.151 101.660 1.00 82.20  ? 430 ALA B C   1 
ATOM   6824 O  O   . ALA B 1 430 ? 140.623 132.944 102.272 1.00 82.20  ? 430 ALA B O   1 
ATOM   6825 C  CB  . ALA B 1 430 ? 137.596 132.464 102.566 1.00 82.20  ? 430 ALA B CB  1 
ATOM   6826 N  N   . ASP B 1 431 ? 140.339 130.945 101.291 1.00 87.08  ? 431 ASP B N   1 
ATOM   6827 C  CA  . ASP B 1 431 ? 141.753 130.616 101.422 1.00 87.08  ? 431 ASP B CA  1 
ATOM   6828 C  C   . ASP B 1 431 ? 142.530 131.013 100.181 1.00 87.08  ? 431 ASP B C   1 
ATOM   6829 O  O   . ASP B 1 431 ? 143.745 131.222 100.242 1.00 87.08  ? 431 ASP B O   1 
ATOM   6830 C  CB  . ASP B 1 431 ? 141.937 129.132 101.702 1.00 87.08  ? 431 ASP B CB  1 
ATOM   6831 C  CG  . ASP B 1 431 ? 141.506 128.758 103.090 1.00 87.08  ? 431 ASP B CG  1 
ATOM   6832 O  OD1 . ASP B 1 431 ? 141.329 129.678 103.907 1.00 87.08  ? 431 ASP B OD1 1 
ATOM   6833 O  OD2 . ASP B 1 431 ? 141.398 127.555 103.376 1.00 87.08  ? 431 ASP B OD2 1 
ATOM   6834 N  N   . ARG B 1 432 ? 141.848 131.127 99.045  1.00 88.05  ? 432 ARG B N   1 
ATOM   6835 C  CA  . ARG B 1 432 ? 142.521 131.585 97.840  1.00 88.05  ? 432 ARG B CA  1 
ATOM   6836 C  C   . ARG B 1 432 ? 142.799 133.079 97.909  1.00 88.05  ? 432 ARG B C   1 
ATOM   6837 O  O   . ARG B 1 432 ? 143.673 133.588 97.201  1.00 88.05  ? 432 ARG B O   1 
ATOM   6838 C  CB  . ARG B 1 432 ? 141.684 131.243 96.614  1.00 88.05  ? 432 ARG B CB  1 
ATOM   6839 C  CG  . ARG B 1 432 ? 142.495 130.739 95.448  1.00 88.05  ? 432 ARG B CG  1 
ATOM   6840 C  CD  . ARG B 1 432 ? 141.663 130.606 94.179  1.00 88.05  ? 432 ARG B CD  1 
ATOM   6841 N  NE  . ARG B 1 432 ? 140.285 130.179 94.417  1.00 88.05  ? 432 ARG B NE  1 
ATOM   6842 C  CZ  . ARG B 1 432 ? 139.908 128.917 94.603  1.00 88.05  ? 432 ARG B CZ  1 
ATOM   6843 N  NH1 . ARG B 1 432 ? 140.803 127.941 94.596  1.00 88.05  ? 432 ARG B NH1 1 
ATOM   6844 N  NH2 . ARG B 1 432 ? 138.632 128.629 94.800  1.00 88.05  ? 432 ARG B NH2 1 
ATOM   6845 N  N   . LEU B 1 433 ? 142.070 133.797 98.755  1.00 85.41  ? 433 LEU B N   1 
ATOM   6846 C  CA  . LEU B 1 433 ? 142.330 135.210 98.973  1.00 85.41  ? 433 LEU B CA  1 
ATOM   6847 C  C   . LEU B 1 433 ? 143.377 135.398 100.058 1.00 85.41  ? 433 LEU B C   1 
ATOM   6848 O  O   . LEU B 1 433 ? 144.185 136.315 99.997  1.00 85.41  ? 433 LEU B O   1 
ATOM   6849 C  CB  . LEU B 1 433 ? 141.049 135.943 99.351  1.00 85.41  ? 433 LEU B CB  1 
ATOM   6850 C  CG  . LEU B 1 433 ? 139.871 135.776 98.397  1.00 85.41  ? 433 LEU B CG  1 
ATOM   6851 C  CD1 . LEU B 1 433 ? 138.602 136.256 99.055  1.00 85.41  ? 433 LEU B CD1 1 
ATOM   6852 C  CD2 . LEU B 1 433 ? 140.114 136.517 97.101  1.00 85.41  ? 433 LEU B CD2 1 
HETATM 6853 MN MN  . MN  C 2 .   ? 106.441 87.631  103.129 1.00 99.22  ? 501 MN  A MN  1 
HETATM 6854 MN MN  . MN  D 2 .   ? 116.903 135.712 103.129 1.00 99.53  ? 501 MN  B MN  1 
# 
