data_8ULJ
# 
_entry.id   8ULJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8ULJ         pdb_00008ulj 10.2210/pdb8ulj/pdb 
WWPDB D_1000278353 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-06 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_database_PDB_caveat.id     1 
_database_PDB_caveat.text   
;The distance between Residue L SER 115 and Residue L PRO 120 is 19.57 Angstrom. But there are only 4 residues (not enough sequence) to cover the gap region.
;
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8ULJ 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wayne.d.harshbarger@gsk.com 
_pdbx_contact_author.name_first         Wayne 
_pdbx_contact_author.name_last          Harshbarger 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1673-0679 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Harshbarger, W.D.' 1 0000-0002-1673-0679 
'Andreano, E.'      2 0000-0003-0088-5788 
'Malito, E.'        3 0000-0002-1669-5607 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   DK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To be published' 
_citation.journal_id_ASTM           ABCRE6 
_citation.journal_id_CSD            0766 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural and functional properties of monoclonal and vaccine-induced antibodies targeting epitopes of emerging RSV variants' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xian, Y.'          1  ? 
primary 'Andreano, E.'      2  ? 
primary 'Tian, S.'          3  ? 
primary 'Phung, E.'         4  ? 
primary 'Garbinski, L.'     5  ? 
primary 'Biancucci, M.'     6  ? 
primary 'Lofano, G.'        7  ? 
primary 'Mallett, C.P.'     8  ? 
primary 'Balsaraf, A.'      9  ? 
primary 'Huang, Y.'         10 ? 
primary 'Buricchi, F.'      11 ? 
primary 'Finco, O.'         12 ? 
primary 'Rappuoli, R.'      13 ? 
primary 'Bottomley, M.J.'   14 ? 
primary 'Chandramouli, S.'  15 ? 
primary 'Warter, L.'        16 ? 
primary 'Williams, J.'      17 ? 
primary 'Malito, E.'        18 ? 
primary 'Harshbarger, W.D.' 19 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Fusion glycoprotein F2'          8873.036  1 ? ? ? ? 
2 polymer man '2E08 Fab Light Chain'            23336.850 1 ? ? ? ? 
3 polymer man '2E08 Fab Heavy Chain'            25919.115 1 ? ? ? 'C-terminal TEV cleavage site and 6 x His tag' 
4 polymer man 'Fusion glycoprotein F0,Fibritin' 45609.148 1 ? ? ? 
;Fibritin trimerization domain fused to C terminus of RSV glycoprotein F1 domain,Fibritin trimerization domain fused to C terminus of RSV glycoprotein F1 domain
;
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 F2                                               
4 'Collar protein,Whisker antigen control protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATN 
QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPATN A ? 
2 'polypeptide(L)' no no 
;EIVTQSPGTLSLSPGERATLSCRASQNVGSNLLAWYQQKPGQAPRLLIYGASNRATGIPDRFSGSGSGTDFTLTISRLEP
EDFVVYHCQQYGSSPRTFGQGTKVEIRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
;EIVTQSPGTLSLSPGERATLSCRASQNVGSNLLAWYQQKPGQAPRLLIYGASNRATGIPDRFSGSGSGTDFTLTISRLEP
EDFVVYHCQQYGSSPRTFGQGTKVEIRRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQ
ESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
;
L ? 
3 'polypeptide(L)' no no 
;QVQLVESGAEAKKPGSSVKVSCKISGGTLNDYPIRWVRQAPGQGLEWMGGIIPILGTSYETQKFQGRLTLTADELTSTVY
MELRYLTSEDAAVYFCATMTSPVFIDALDVWGQGTRVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKGSENLYFQGSHHHH
HH
;
;QVQLVESGAEAKKPGSSVKVSCKISGGTLNDYPIRWVRQAPGQGLEWMGGIIPILGTSYETQKFQGRLTLTADELTSTVY
MELRYLTSEDAAVYFCATMTSPVFIDALDVWGQGTRVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTV
SWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPKSCDKGSENLYFQGSHHHH
HH
;
H ? 
4 'polypeptide(L)' no no 
;FLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISN
IETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEV
LAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLP
SEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTL
YYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGE
WVLLSTFLGGLVPR
;
;FLGFLLGVGSAIASGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTFKVLDLKNYIDKQLLPILNKQSCSISN
IETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMCIIKEEV
LAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLP
SEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTL
YYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELLSAIGGYIPEAPRDGQAYVRKDGE
WVLLSTFLGGLVPR
;
B ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   ASN n 
1 3   ILE n 
1 4   THR n 
1 5   GLU n 
1 6   GLU n 
1 7   PHE n 
1 8   TYR n 
1 9   GLN n 
1 10  SER n 
1 11  THR n 
1 12  CYS n 
1 13  SER n 
1 14  ALA n 
1 15  VAL n 
1 16  SER n 
1 17  LYS n 
1 18  GLY n 
1 19  TYR n 
1 20  LEU n 
1 21  SER n 
1 22  ALA n 
1 23  LEU n 
1 24  ARG n 
1 25  THR n 
1 26  GLY n 
1 27  TRP n 
1 28  TYR n 
1 29  THR n 
1 30  SER n 
1 31  VAL n 
1 32  ILE n 
1 33  THR n 
1 34  ILE n 
1 35  GLU n 
1 36  LEU n 
1 37  SER n 
1 38  ASN n 
1 39  ILE n 
1 40  LYS n 
1 41  GLU n 
1 42  ASN n 
1 43  LYS n 
1 44  CYS n 
1 45  ASN n 
1 46  GLY n 
1 47  THR n 
1 48  ASP n 
1 49  ALA n 
1 50  LYS n 
1 51  VAL n 
1 52  LYS n 
1 53  LEU n 
1 54  ILE n 
1 55  LYS n 
1 56  GLN n 
1 57  GLU n 
1 58  LEU n 
1 59  ASP n 
1 60  LYS n 
1 61  TYR n 
1 62  LYS n 
1 63  ASN n 
1 64  ALA n 
1 65  VAL n 
1 66  THR n 
1 67  GLU n 
1 68  LEU n 
1 69  GLN n 
1 70  LEU n 
1 71  LEU n 
1 72  MET n 
1 73  GLN n 
1 74  SER n 
1 75  THR n 
1 76  PRO n 
1 77  ALA n 
1 78  THR n 
1 79  ASN n 
2 1   GLU n 
2 2   ILE n 
2 3   VAL n 
2 4   THR n 
2 5   GLN n 
2 6   SER n 
2 7   PRO n 
2 8   GLY n 
2 9   THR n 
2 10  LEU n 
2 11  SER n 
2 12  LEU n 
2 13  SER n 
2 14  PRO n 
2 15  GLY n 
2 16  GLU n 
2 17  ARG n 
2 18  ALA n 
2 19  THR n 
2 20  LEU n 
2 21  SER n 
2 22  CYS n 
2 23  ARG n 
2 24  ALA n 
2 25  SER n 
2 26  GLN n 
2 27  ASN n 
2 28  VAL n 
2 29  GLY n 
2 30  SER n 
2 31  ASN n 
2 32  LEU n 
2 33  LEU n 
2 34  ALA n 
2 35  TRP n 
2 36  TYR n 
2 37  GLN n 
2 38  GLN n 
2 39  LYS n 
2 40  PRO n 
2 41  GLY n 
2 42  GLN n 
2 43  ALA n 
2 44  PRO n 
2 45  ARG n 
2 46  LEU n 
2 47  LEU n 
2 48  ILE n 
2 49  TYR n 
2 50  GLY n 
2 51  ALA n 
2 52  SER n 
2 53  ASN n 
2 54  ARG n 
2 55  ALA n 
2 56  THR n 
2 57  GLY n 
2 58  ILE n 
2 59  PRO n 
2 60  ASP n 
2 61  ARG n 
2 62  PHE n 
2 63  SER n 
2 64  GLY n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  THR n 
2 70  ASP n 
2 71  PHE n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  ILE n 
2 76  SER n 
2 77  ARG n 
2 78  LEU n 
2 79  GLU n 
2 80  PRO n 
2 81  GLU n 
2 82  ASP n 
2 83  PHE n 
2 84  VAL n 
2 85  VAL n 
2 86  TYR n 
2 87  HIS n 
2 88  CYS n 
2 89  GLN n 
2 90  GLN n 
2 91  TYR n 
2 92  GLY n 
2 93  SER n 
2 94  SER n 
2 95  PRO n 
2 96  ARG n 
2 97  THR n 
2 98  PHE n 
2 99  GLY n 
2 100 GLN n 
2 101 GLY n 
2 102 THR n 
2 103 LYS n 
2 104 VAL n 
2 105 GLU n 
2 106 ILE n 
2 107 ARG n 
2 108 ARG n 
2 109 THR n 
2 110 VAL n 
2 111 ALA n 
2 112 ALA n 
2 113 PRO n 
2 114 SER n 
2 115 VAL n 
2 116 PHE n 
2 117 ILE n 
2 118 PHE n 
2 119 PRO n 
2 120 PRO n 
2 121 SER n 
2 122 ASP n 
2 123 GLU n 
2 124 GLN n 
2 125 LEU n 
2 126 LYS n 
2 127 SER n 
2 128 GLY n 
2 129 THR n 
2 130 ALA n 
2 131 SER n 
2 132 VAL n 
2 133 VAL n 
2 134 CYS n 
2 135 LEU n 
2 136 LEU n 
2 137 ASN n 
2 138 ASN n 
2 139 PHE n 
2 140 TYR n 
2 141 PRO n 
2 142 ARG n 
2 143 GLU n 
2 144 ALA n 
2 145 LYS n 
2 146 VAL n 
2 147 GLN n 
2 148 TRP n 
2 149 LYS n 
2 150 VAL n 
2 151 ASP n 
2 152 ASN n 
2 153 ALA n 
2 154 LEU n 
2 155 GLN n 
2 156 SER n 
2 157 GLY n 
2 158 ASN n 
2 159 SER n 
2 160 GLN n 
2 161 GLU n 
2 162 SER n 
2 163 VAL n 
2 164 THR n 
2 165 GLU n 
2 166 GLN n 
2 167 ASP n 
2 168 SER n 
2 169 LYS n 
2 170 ASP n 
2 171 SER n 
2 172 THR n 
2 173 TYR n 
2 174 SER n 
2 175 LEU n 
2 176 SER n 
2 177 SER n 
2 178 THR n 
2 179 LEU n 
2 180 THR n 
2 181 LEU n 
2 182 SER n 
2 183 LYS n 
2 184 ALA n 
2 185 ASP n 
2 186 TYR n 
2 187 GLU n 
2 188 LYS n 
2 189 HIS n 
2 190 LYS n 
2 191 VAL n 
2 192 TYR n 
2 193 ALA n 
2 194 CYS n 
2 195 GLU n 
2 196 VAL n 
2 197 THR n 
2 198 HIS n 
2 199 GLN n 
2 200 GLY n 
2 201 LEU n 
2 202 SER n 
2 203 SER n 
2 204 PRO n 
2 205 VAL n 
2 206 THR n 
2 207 LYS n 
2 208 SER n 
2 209 PHE n 
2 210 ASN n 
2 211 ARG n 
2 212 GLY n 
2 213 GLU n 
2 214 CYS n 
3 1   GLN n 
3 2   VAL n 
3 3   GLN n 
3 4   LEU n 
3 5   VAL n 
3 6   GLU n 
3 7   SER n 
3 8   GLY n 
3 9   ALA n 
3 10  GLU n 
3 11  ALA n 
3 12  LYS n 
3 13  LYS n 
3 14  PRO n 
3 15  GLY n 
3 16  SER n 
3 17  SER n 
3 18  VAL n 
3 19  LYS n 
3 20  VAL n 
3 21  SER n 
3 22  CYS n 
3 23  LYS n 
3 24  ILE n 
3 25  SER n 
3 26  GLY n 
3 27  GLY n 
3 28  THR n 
3 29  LEU n 
3 30  ASN n 
3 31  ASP n 
3 32  TYR n 
3 33  PRO n 
3 34  ILE n 
3 35  ARG n 
3 36  TRP n 
3 37  VAL n 
3 38  ARG n 
3 39  GLN n 
3 40  ALA n 
3 41  PRO n 
3 42  GLY n 
3 43  GLN n 
3 44  GLY n 
3 45  LEU n 
3 46  GLU n 
3 47  TRP n 
3 48  MET n 
3 49  GLY n 
3 50  GLY n 
3 51  ILE n 
3 52  ILE n 
3 53  PRO n 
3 54  ILE n 
3 55  LEU n 
3 56  GLY n 
3 57  THR n 
3 58  SER n 
3 59  TYR n 
3 60  GLU n 
3 61  THR n 
3 62  GLN n 
3 63  LYS n 
3 64  PHE n 
3 65  GLN n 
3 66  GLY n 
3 67  ARG n 
3 68  LEU n 
3 69  THR n 
3 70  LEU n 
3 71  THR n 
3 72  ALA n 
3 73  ASP n 
3 74  GLU n 
3 75  LEU n 
3 76  THR n 
3 77  SER n 
3 78  THR n 
3 79  VAL n 
3 80  TYR n 
3 81  MET n 
3 82  GLU n 
3 83  LEU n 
3 84  ARG n 
3 85  TYR n 
3 86  LEU n 
3 87  THR n 
3 88  SER n 
3 89  GLU n 
3 90  ASP n 
3 91  ALA n 
3 92  ALA n 
3 93  VAL n 
3 94  TYR n 
3 95  PHE n 
3 96  CYS n 
3 97  ALA n 
3 98  THR n 
3 99  MET n 
3 100 THR n 
3 101 SER n 
3 102 PRO n 
3 103 VAL n 
3 104 PHE n 
3 105 ILE n 
3 106 ASP n 
3 107 ALA n 
3 108 LEU n 
3 109 ASP n 
3 110 VAL n 
3 111 TRP n 
3 112 GLY n 
3 113 GLN n 
3 114 GLY n 
3 115 THR n 
3 116 ARG n 
3 117 VAL n 
3 118 THR n 
3 119 VAL n 
3 120 SER n 
3 121 SER n 
3 122 ALA n 
3 123 SER n 
3 124 THR n 
3 125 LYS n 
3 126 GLY n 
3 127 PRO n 
3 128 SER n 
3 129 VAL n 
3 130 PHE n 
3 131 PRO n 
3 132 LEU n 
3 133 ALA n 
3 134 PRO n 
3 135 SER n 
3 136 SER n 
3 137 LYS n 
3 138 SER n 
3 139 THR n 
3 140 SER n 
3 141 GLY n 
3 142 GLY n 
3 143 THR n 
3 144 ALA n 
3 145 ALA n 
3 146 LEU n 
3 147 GLY n 
3 148 CYS n 
3 149 LEU n 
3 150 VAL n 
3 151 LYS n 
3 152 ASP n 
3 153 TYR n 
3 154 PHE n 
3 155 PRO n 
3 156 GLU n 
3 157 PRO n 
3 158 VAL n 
3 159 THR n 
3 160 VAL n 
3 161 SER n 
3 162 TRP n 
3 163 ASN n 
3 164 SER n 
3 165 GLY n 
3 166 ALA n 
3 167 LEU n 
3 168 THR n 
3 169 SER n 
3 170 GLY n 
3 171 VAL n 
3 172 HIS n 
3 173 THR n 
3 174 PHE n 
3 175 PRO n 
3 176 ALA n 
3 177 VAL n 
3 178 LEU n 
3 179 GLN n 
3 180 SER n 
3 181 SER n 
3 182 GLY n 
3 183 LEU n 
3 184 TYR n 
3 185 SER n 
3 186 LEU n 
3 187 SER n 
3 188 SER n 
3 189 VAL n 
3 190 VAL n 
3 191 THR n 
3 192 VAL n 
3 193 PRO n 
3 194 SER n 
3 195 SER n 
3 196 SER n 
3 197 LEU n 
3 198 GLY n 
3 199 THR n 
3 200 GLN n 
3 201 THR n 
3 202 TYR n 
3 203 ILE n 
3 204 CYS n 
3 205 ASN n 
3 206 VAL n 
3 207 ASN n 
3 208 HIS n 
3 209 LYS n 
3 210 PRO n 
3 211 SER n 
3 212 ASN n 
3 213 THR n 
3 214 LYS n 
3 215 VAL n 
3 216 ASP n 
3 217 LYS n 
3 218 ARG n 
3 219 VAL n 
3 220 GLU n 
3 221 PRO n 
3 222 LYS n 
3 223 SER n 
3 224 CYS n 
3 225 ASP n 
3 226 LYS n 
3 227 GLY n 
3 228 SER n 
3 229 GLU n 
3 230 ASN n 
3 231 LEU n 
3 232 TYR n 
3 233 PHE n 
3 234 GLN n 
3 235 GLY n 
3 236 SER n 
3 237 HIS n 
3 238 HIS n 
3 239 HIS n 
3 240 HIS n 
3 241 HIS n 
3 242 HIS n 
4 1   PHE n 
4 2   LEU n 
4 3   GLY n 
4 4   PHE n 
4 5   LEU n 
4 6   LEU n 
4 7   GLY n 
4 8   VAL n 
4 9   GLY n 
4 10  SER n 
4 11  ALA n 
4 12  ILE n 
4 13  ALA n 
4 14  SER n 
4 15  GLY n 
4 16  VAL n 
4 17  ALA n 
4 18  VAL n 
4 19  CYS n 
4 20  LYS n 
4 21  VAL n 
4 22  LEU n 
4 23  HIS n 
4 24  LEU n 
4 25  GLU n 
4 26  GLY n 
4 27  GLU n 
4 28  VAL n 
4 29  ASN n 
4 30  LYS n 
4 31  ILE n 
4 32  LYS n 
4 33  SER n 
4 34  ALA n 
4 35  LEU n 
4 36  LEU n 
4 37  SER n 
4 38  THR n 
4 39  ASN n 
4 40  LYS n 
4 41  ALA n 
4 42  VAL n 
4 43  VAL n 
4 44  SER n 
4 45  LEU n 
4 46  SER n 
4 47  ASN n 
4 48  GLY n 
4 49  VAL n 
4 50  SER n 
4 51  VAL n 
4 52  LEU n 
4 53  THR n 
4 54  PHE n 
4 55  LYS n 
4 56  VAL n 
4 57  LEU n 
4 58  ASP n 
4 59  LEU n 
4 60  LYS n 
4 61  ASN n 
4 62  TYR n 
4 63  ILE n 
4 64  ASP n 
4 65  LYS n 
4 66  GLN n 
4 67  LEU n 
4 68  LEU n 
4 69  PRO n 
4 70  ILE n 
4 71  LEU n 
4 72  ASN n 
4 73  LYS n 
4 74  GLN n 
4 75  SER n 
4 76  CYS n 
4 77  SER n 
4 78  ILE n 
4 79  SER n 
4 80  ASN n 
4 81  ILE n 
4 82  GLU n 
4 83  THR n 
4 84  VAL n 
4 85  ILE n 
4 86  GLU n 
4 87  PHE n 
4 88  GLN n 
4 89  GLN n 
4 90  LYS n 
4 91  ASN n 
4 92  ASN n 
4 93  ARG n 
4 94  LEU n 
4 95  LEU n 
4 96  GLU n 
4 97  ILE n 
4 98  THR n 
4 99  ARG n 
4 100 GLU n 
4 101 PHE n 
4 102 SER n 
4 103 VAL n 
4 104 ASN n 
4 105 ALA n 
4 106 GLY n 
4 107 VAL n 
4 108 THR n 
4 109 THR n 
4 110 PRO n 
4 111 VAL n 
4 112 SER n 
4 113 THR n 
4 114 TYR n 
4 115 MET n 
4 116 LEU n 
4 117 THR n 
4 118 ASN n 
4 119 SER n 
4 120 GLU n 
4 121 LEU n 
4 122 LEU n 
4 123 SER n 
4 124 LEU n 
4 125 ILE n 
4 126 ASN n 
4 127 ASP n 
4 128 MET n 
4 129 PRO n 
4 130 ILE n 
4 131 THR n 
4 132 ASN n 
4 133 ASP n 
4 134 GLN n 
4 135 LYS n 
4 136 LYS n 
4 137 LEU n 
4 138 MET n 
4 139 SER n 
4 140 ASN n 
4 141 ASN n 
4 142 VAL n 
4 143 GLN n 
4 144 ILE n 
4 145 VAL n 
4 146 ARG n 
4 147 GLN n 
4 148 GLN n 
4 149 SER n 
4 150 TYR n 
4 151 SER n 
4 152 ILE n 
4 153 MET n 
4 154 CYS n 
4 155 ILE n 
4 156 ILE n 
4 157 LYS n 
4 158 GLU n 
4 159 GLU n 
4 160 VAL n 
4 161 LEU n 
4 162 ALA n 
4 163 TYR n 
4 164 VAL n 
4 165 VAL n 
4 166 GLN n 
4 167 LEU n 
4 168 PRO n 
4 169 LEU n 
4 170 TYR n 
4 171 GLY n 
4 172 VAL n 
4 173 ILE n 
4 174 ASP n 
4 175 THR n 
4 176 PRO n 
4 177 CYS n 
4 178 TRP n 
4 179 LYS n 
4 180 LEU n 
4 181 HIS n 
4 182 THR n 
4 183 SER n 
4 184 PRO n 
4 185 LEU n 
4 186 CYS n 
4 187 THR n 
4 188 THR n 
4 189 ASN n 
4 190 THR n 
4 191 LYS n 
4 192 GLU n 
4 193 GLY n 
4 194 SER n 
4 195 ASN n 
4 196 ILE n 
4 197 CYS n 
4 198 LEU n 
4 199 THR n 
4 200 ARG n 
4 201 THR n 
4 202 ASP n 
4 203 ARG n 
4 204 GLY n 
4 205 TRP n 
4 206 TYR n 
4 207 CYS n 
4 208 ASP n 
4 209 ASN n 
4 210 ALA n 
4 211 GLY n 
4 212 SER n 
4 213 VAL n 
4 214 SER n 
4 215 PHE n 
4 216 PHE n 
4 217 PRO n 
4 218 GLN n 
4 219 ALA n 
4 220 GLU n 
4 221 THR n 
4 222 CYS n 
4 223 LYS n 
4 224 VAL n 
4 225 GLN n 
4 226 SER n 
4 227 ASN n 
4 228 ARG n 
4 229 VAL n 
4 230 PHE n 
4 231 CYS n 
4 232 ASP n 
4 233 THR n 
4 234 MET n 
4 235 ASN n 
4 236 SER n 
4 237 LEU n 
4 238 THR n 
4 239 LEU n 
4 240 PRO n 
4 241 SER n 
4 242 GLU n 
4 243 VAL n 
4 244 ASN n 
4 245 LEU n 
4 246 CYS n 
4 247 ASN n 
4 248 VAL n 
4 249 ASP n 
4 250 ILE n 
4 251 PHE n 
4 252 ASN n 
4 253 PRO n 
4 254 LYS n 
4 255 TYR n 
4 256 ASP n 
4 257 CYS n 
4 258 LYS n 
4 259 ILE n 
4 260 MET n 
4 261 THR n 
4 262 SER n 
4 263 LYS n 
4 264 THR n 
4 265 ASP n 
4 266 VAL n 
4 267 SER n 
4 268 SER n 
4 269 SER n 
4 270 VAL n 
4 271 ILE n 
4 272 THR n 
4 273 SER n 
4 274 LEU n 
4 275 GLY n 
4 276 ALA n 
4 277 ILE n 
4 278 VAL n 
4 279 SER n 
4 280 CYS n 
4 281 TYR n 
4 282 GLY n 
4 283 LYS n 
4 284 THR n 
4 285 LYS n 
4 286 CYS n 
4 287 THR n 
4 288 ALA n 
4 289 SER n 
4 290 ASN n 
4 291 LYS n 
4 292 ASN n 
4 293 ARG n 
4 294 GLY n 
4 295 ILE n 
4 296 ILE n 
4 297 LYS n 
4 298 THR n 
4 299 PHE n 
4 300 SER n 
4 301 ASN n 
4 302 GLY n 
4 303 CYS n 
4 304 ASP n 
4 305 TYR n 
4 306 VAL n 
4 307 SER n 
4 308 ASN n 
4 309 LYS n 
4 310 GLY n 
4 311 VAL n 
4 312 ASP n 
4 313 THR n 
4 314 VAL n 
4 315 SER n 
4 316 VAL n 
4 317 GLY n 
4 318 ASN n 
4 319 THR n 
4 320 LEU n 
4 321 TYR n 
4 322 TYR n 
4 323 VAL n 
4 324 ASN n 
4 325 LYS n 
4 326 GLN n 
4 327 GLU n 
4 328 GLY n 
4 329 LYS n 
4 330 SER n 
4 331 LEU n 
4 332 TYR n 
4 333 VAL n 
4 334 LYS n 
4 335 GLY n 
4 336 GLU n 
4 337 PRO n 
4 338 ILE n 
4 339 ILE n 
4 340 ASN n 
4 341 PHE n 
4 342 TYR n 
4 343 ASP n 
4 344 PRO n 
4 345 LEU n 
4 346 VAL n 
4 347 PHE n 
4 348 PRO n 
4 349 SER n 
4 350 ASP n 
4 351 GLU n 
4 352 PHE n 
4 353 ASP n 
4 354 ALA n 
4 355 SER n 
4 356 ILE n 
4 357 SER n 
4 358 GLN n 
4 359 VAL n 
4 360 ASN n 
4 361 GLU n 
4 362 LYS n 
4 363 ILE n 
4 364 ASN n 
4 365 GLN n 
4 366 SER n 
4 367 LEU n 
4 368 ALA n 
4 369 PHE n 
4 370 ILE n 
4 371 ARG n 
4 372 LYS n 
4 373 SER n 
4 374 ASP n 
4 375 GLU n 
4 376 LEU n 
4 377 LEU n 
4 378 SER n 
4 379 ALA n 
4 380 ILE n 
4 381 GLY n 
4 382 GLY n 
4 383 TYR n 
4 384 ILE n 
4 385 PRO n 
4 386 GLU n 
4 387 ALA n 
4 388 PRO n 
4 389 ARG n 
4 390 ASP n 
4 391 GLY n 
4 392 GLN n 
4 393 ALA n 
4 394 TYR n 
4 395 VAL n 
4 396 ARG n 
4 397 LYS n 
4 398 ASP n 
4 399 GLY n 
4 400 GLU n 
4 401 TRP n 
4 402 VAL n 
4 403 LEU n 
4 404 LEU n 
4 405 SER n 
4 406 THR n 
4 407 PHE n 
4 408 LEU n 
4 409 GLY n 
4 410 GLY n 
4 411 LEU n 
4 412 VAL n 
4 413 PRO n 
4 414 ARG n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   79  ? ? ?   ? ? ? ? ? ? 'Respiratory syncytial virus A2' 1972429 ? ? ? ? ? ? ? ? 
'Cricetulus griseus' 10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   214 ? ? ?   ? ? ? ? ? ? 'Homo sapiens'                   9606    ? ? ? ? ? ? ? ? 
'Homo sapiens'       9606  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   242 ? ? ?   ? ? ? ? ? ? 'Homo sapiens'                   9606    ? ? ? ? ? ? ? ? 
'Homo sapiens'       9606  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   377 ? ? ?   ? ? ? ? ? ? 'Respiratory syncytial virus A2' 1972429 ? ? ? ? ? ? ? ? 
'Cricetulus griseus' 10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 2 sample 'Biological sequence' 378 414 ? ? wac ? ? ? ? ? ? 'Respiratory syncytial virus A2' 1972429 ? ? ? ? ? ? ? ? 
'Cricetulus griseus' 10029 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   26  ?   ?   ?   A . n 
A 1 2   ASN 2   27  27  ASN ASN A . n 
A 1 3   ILE 3   28  28  ILE ILE A . n 
A 1 4   THR 4   29  29  THR THR A . n 
A 1 5   GLU 5   30  30  GLU GLU A . n 
A 1 6   GLU 6   31  31  GLU GLU A . n 
A 1 7   PHE 7   32  32  PHE PHE A . n 
A 1 8   TYR 8   33  33  TYR TYR A . n 
A 1 9   GLN 9   34  34  GLN GLN A . n 
A 1 10  SER 10  35  35  SER SER A . n 
A 1 11  THR 11  36  36  THR THR A . n 
A 1 12  CYS 12  37  37  CYS CYS A . n 
A 1 13  SER 13  38  38  SER SER A . n 
A 1 14  ALA 14  39  39  ALA ALA A . n 
A 1 15  VAL 15  40  40  VAL VAL A . n 
A 1 16  SER 16  41  41  SER SER A . n 
A 1 17  LYS 17  42  42  LYS LYS A . n 
A 1 18  GLY 18  43  43  GLY GLY A . n 
A 1 19  TYR 19  44  44  TYR TYR A . n 
A 1 20  LEU 20  45  45  LEU LEU A . n 
A 1 21  SER 21  46  46  SER SER A . n 
A 1 22  ALA 22  47  47  ALA ALA A . n 
A 1 23  LEU 23  48  48  LEU LEU A . n 
A 1 24  ARG 24  49  49  ARG ARG A . n 
A 1 25  THR 25  50  50  THR THR A . n 
A 1 26  GLY 26  51  51  GLY GLY A . n 
A 1 27  TRP 27  52  52  TRP TRP A . n 
A 1 28  TYR 28  53  53  TYR TYR A . n 
A 1 29  THR 29  54  54  THR THR A . n 
A 1 30  SER 30  55  55  SER SER A . n 
A 1 31  VAL 31  56  56  VAL VAL A . n 
A 1 32  ILE 32  57  57  ILE ILE A . n 
A 1 33  THR 33  58  58  THR THR A . n 
A 1 34  ILE 34  59  59  ILE ILE A . n 
A 1 35  GLU 35  60  60  GLU GLU A . n 
A 1 36  LEU 36  61  61  LEU LEU A . n 
A 1 37  SER 37  62  62  SER SER A . n 
A 1 38  ASN 38  63  63  ASN ASN A . n 
A 1 39  ILE 39  64  64  ILE ILE A . n 
A 1 40  LYS 40  65  65  LYS LYS A . n 
A 1 41  GLU 41  66  66  GLU GLU A . n 
A 1 42  ASN 42  67  67  ASN ASN A . n 
A 1 43  LYS 43  68  68  LYS LYS A . n 
A 1 44  CYS 44  69  69  CYS CYS A . n 
A 1 45  ASN 45  70  70  ASN ASN A . n 
A 1 46  GLY 46  71  71  GLY GLY A . n 
A 1 47  THR 47  72  72  THR THR A . n 
A 1 48  ASP 48  73  73  ASP ASP A . n 
A 1 49  ALA 49  74  74  ALA ALA A . n 
A 1 50  LYS 50  75  75  LYS LYS A . n 
A 1 51  VAL 51  76  76  VAL VAL A . n 
A 1 52  LYS 52  77  77  LYS LYS A . n 
A 1 53  LEU 53  78  78  LEU LEU A . n 
A 1 54  ILE 54  79  79  ILE ILE A . n 
A 1 55  LYS 55  80  80  LYS LYS A . n 
A 1 56  GLN 56  81  81  GLN GLN A . n 
A 1 57  GLU 57  82  82  GLU GLU A . n 
A 1 58  LEU 58  83  83  LEU LEU A . n 
A 1 59  ASP 59  84  84  ASP ASP A . n 
A 1 60  LYS 60  85  85  LYS LYS A . n 
A 1 61  TYR 61  86  86  TYR TYR A . n 
A 1 62  LYS 62  87  87  LYS LYS A . n 
A 1 63  ASN 63  88  88  ASN ASN A . n 
A 1 64  ALA 64  89  89  ALA ALA A . n 
A 1 65  VAL 65  90  90  VAL VAL A . n 
A 1 66  THR 66  91  91  THR THR A . n 
A 1 67  GLU 67  92  92  GLU GLU A . n 
A 1 68  LEU 68  93  93  LEU LEU A . n 
A 1 69  GLN 69  94  94  GLN GLN A . n 
A 1 70  LEU 70  95  95  LEU LEU A . n 
A 1 71  LEU 71  96  96  LEU LEU A . n 
A 1 72  MET 72  97  97  MET MET A . n 
A 1 73  GLN 73  98  98  GLN GLN A . n 
A 1 74  SER 74  99  99  SER SER A . n 
A 1 75  THR 75  100 100 THR THR A . n 
A 1 76  PRO 76  101 101 PRO PRO A . n 
A 1 77  ALA 77  102 102 ALA ALA A . n 
A 1 78  THR 78  103 103 THR THR A . n 
A 1 79  ASN 79  104 104 ASN ASN A . n 
B 2 1   GLU 1   2   2   GLU GLU L . n 
B 2 2   ILE 2   3   3   ILE ILE L . n 
B 2 3   VAL 3   4   4   VAL VAL L . n 
B 2 4   THR 4   5   5   THR THR L . n 
B 2 5   GLN 5   6   6   GLN GLN L . n 
B 2 6   SER 6   7   7   SER SER L . n 
B 2 7   PRO 7   8   8   PRO PRO L . n 
B 2 8   GLY 8   9   9   GLY GLY L . n 
B 2 9   THR 9   10  10  THR THR L . n 
B 2 10  LEU 10  11  11  LEU LEU L . n 
B 2 11  SER 11  12  12  SER SER L . n 
B 2 12  LEU 12  13  13  LEU LEU L . n 
B 2 13  SER 13  14  14  SER SER L . n 
B 2 14  PRO 14  15  15  PRO PRO L . n 
B 2 15  GLY 15  16  16  GLY GLY L . n 
B 2 16  GLU 16  17  17  GLU GLU L . n 
B 2 17  ARG 17  18  18  ARG ARG L . n 
B 2 18  ALA 18  19  19  ALA ALA L . n 
B 2 19  THR 19  20  20  THR THR L . n 
B 2 20  LEU 20  21  21  LEU LEU L . n 
B 2 21  SER 21  22  22  SER SER L . n 
B 2 22  CYS 22  23  23  CYS CYS L . n 
B 2 23  ARG 23  24  24  ARG ARG L . n 
B 2 24  ALA 24  25  25  ALA ALA L . n 
B 2 25  SER 25  26  26  SER SER L . n 
B 2 26  GLN 26  27  27  GLN GLN L . n 
B 2 27  ASN 27  28  28  ASN ASN L . n 
B 2 28  VAL 28  29  29  VAL VAL L . n 
B 2 29  GLY 29  30  30  GLY GLY L . n 
B 2 30  SER 30  31  31  SER SER L . n 
B 2 31  ASN 31  32  32  ASN ASN L . n 
B 2 32  LEU 32  33  33  LEU LEU L . n 
B 2 33  LEU 33  34  34  LEU LEU L . n 
B 2 34  ALA 34  35  35  ALA ALA L . n 
B 2 35  TRP 35  36  36  TRP TRP L . n 
B 2 36  TYR 36  37  37  TYR TYR L . n 
B 2 37  GLN 37  38  38  GLN GLN L . n 
B 2 38  GLN 38  39  39  GLN GLN L . n 
B 2 39  LYS 39  40  40  LYS LYS L . n 
B 2 40  PRO 40  41  41  PRO PRO L . n 
B 2 41  GLY 41  42  42  GLY GLY L . n 
B 2 42  GLN 42  43  43  GLN GLN L . n 
B 2 43  ALA 43  44  44  ALA ALA L . n 
B 2 44  PRO 44  45  45  PRO PRO L . n 
B 2 45  ARG 45  46  46  ARG ARG L . n 
B 2 46  LEU 46  47  47  LEU LEU L . n 
B 2 47  LEU 47  48  48  LEU LEU L . n 
B 2 48  ILE 48  49  49  ILE ILE L . n 
B 2 49  TYR 49  50  50  TYR TYR L . n 
B 2 50  GLY 50  51  51  GLY GLY L . n 
B 2 51  ALA 51  52  52  ALA ALA L . n 
B 2 52  SER 52  53  53  SER SER L . n 
B 2 53  ASN 53  54  54  ASN ASN L . n 
B 2 54  ARG 54  55  55  ARG ARG L . n 
B 2 55  ALA 55  56  56  ALA ALA L . n 
B 2 56  THR 56  57  57  THR THR L . n 
B 2 57  GLY 57  58  58  GLY GLY L . n 
B 2 58  ILE 58  59  59  ILE ILE L . n 
B 2 59  PRO 59  60  60  PRO PRO L . n 
B 2 60  ASP 60  61  61  ASP ASP L . n 
B 2 61  ARG 61  62  62  ARG ARG L . n 
B 2 62  PHE 62  63  63  PHE PHE L . n 
B 2 63  SER 63  64  64  SER SER L . n 
B 2 64  GLY 64  65  65  GLY GLY L . n 
B 2 65  SER 65  66  66  SER SER L . n 
B 2 66  GLY 66  67  67  GLY GLY L . n 
B 2 67  SER 67  68  68  SER SER L . n 
B 2 68  GLY 68  69  69  GLY GLY L . n 
B 2 69  THR 69  70  70  THR THR L . n 
B 2 70  ASP 70  71  71  ASP ASP L . n 
B 2 71  PHE 71  72  72  PHE PHE L . n 
B 2 72  THR 72  73  73  THR THR L . n 
B 2 73  LEU 73  74  74  LEU LEU L . n 
B 2 74  THR 74  75  75  THR THR L . n 
B 2 75  ILE 75  76  76  ILE ILE L . n 
B 2 76  SER 76  77  77  SER SER L . n 
B 2 77  ARG 77  78  78  ARG ARG L . n 
B 2 78  LEU 78  79  79  LEU LEU L . n 
B 2 79  GLU 79  80  80  GLU GLU L . n 
B 2 80  PRO 80  81  81  PRO PRO L . n 
B 2 81  GLU 81  82  82  GLU GLU L . n 
B 2 82  ASP 82  83  83  ASP ASP L . n 
B 2 83  PHE 83  84  84  PHE PHE L . n 
B 2 84  VAL 84  85  85  VAL VAL L . n 
B 2 85  VAL 85  86  86  VAL VAL L . n 
B 2 86  TYR 86  87  87  TYR TYR L . n 
B 2 87  HIS 87  88  88  HIS HIS L . n 
B 2 88  CYS 88  89  89  CYS CYS L . n 
B 2 89  GLN 89  90  90  GLN GLN L . n 
B 2 90  GLN 90  91  91  GLN GLN L . n 
B 2 91  TYR 91  92  92  TYR TYR L . n 
B 2 92  GLY 92  93  93  GLY GLY L . n 
B 2 93  SER 93  94  94  SER SER L . n 
B 2 94  SER 94  95  95  SER SER L . n 
B 2 95  PRO 95  96  96  PRO PRO L . n 
B 2 96  ARG 96  97  97  ARG ARG L . n 
B 2 97  THR 97  98  98  THR THR L . n 
B 2 98  PHE 98  99  99  PHE PHE L . n 
B 2 99  GLY 99  100 100 GLY GLY L . n 
B 2 100 GLN 100 101 101 GLN GLN L . n 
B 2 101 GLY 101 102 102 GLY GLY L . n 
B 2 102 THR 102 103 103 THR THR L . n 
B 2 103 LYS 103 104 104 LYS LYS L . n 
B 2 104 VAL 104 105 105 VAL VAL L . n 
B 2 105 GLU 105 106 106 GLU GLU L . n 
B 2 106 ILE 106 107 107 ILE ILE L . n 
B 2 107 ARG 107 108 108 ARG ARG L . n 
B 2 108 ARG 108 109 109 ARG ARG L . n 
B 2 109 THR 109 110 110 THR THR L . n 
B 2 110 VAL 110 111 111 VAL VAL L . n 
B 2 111 ALA 111 112 112 ALA ALA L . n 
B 2 112 ALA 112 113 113 ALA ALA L . n 
B 2 113 PRO 113 114 114 PRO PRO L . n 
B 2 114 SER 114 115 115 SER SER L . n 
B 2 115 VAL 115 116 ?   ?   ?   L . n 
B 2 116 PHE 116 117 ?   ?   ?   L . n 
B 2 117 ILE 117 118 ?   ?   ?   L . n 
B 2 118 PHE 118 119 ?   ?   ?   L . n 
B 2 119 PRO 119 120 120 PRO PRO L . n 
B 2 120 PRO 120 121 121 PRO PRO L . n 
B 2 121 SER 121 122 122 SER SER L . n 
B 2 122 ASP 122 123 123 ASP ASP L . n 
B 2 123 GLU 123 124 124 GLU GLU L . n 
B 2 124 GLN 124 125 125 GLN GLN L . n 
B 2 125 LEU 125 126 126 LEU LEU L . n 
B 2 126 LYS 126 127 127 LYS LYS L . n 
B 2 127 SER 127 128 128 SER SER L . n 
B 2 128 GLY 128 129 129 GLY GLY L . n 
B 2 129 THR 129 130 130 THR THR L . n 
B 2 130 ALA 130 131 131 ALA ALA L . n 
B 2 131 SER 131 132 132 SER SER L . n 
B 2 132 VAL 132 133 133 VAL VAL L . n 
B 2 133 VAL 133 134 134 VAL VAL L . n 
B 2 134 CYS 134 135 135 CYS CYS L . n 
B 2 135 LEU 135 136 136 LEU LEU L . n 
B 2 136 LEU 136 137 137 LEU LEU L . n 
B 2 137 ASN 137 138 138 ASN ASN L . n 
B 2 138 ASN 138 139 139 ASN ASN L . n 
B 2 139 PHE 139 140 140 PHE PHE L . n 
B 2 140 TYR 140 141 141 TYR TYR L . n 
B 2 141 PRO 141 142 142 PRO PRO L . n 
B 2 142 ARG 142 143 143 ARG ARG L . n 
B 2 143 GLU 143 144 144 GLU GLU L . n 
B 2 144 ALA 144 145 145 ALA ALA L . n 
B 2 145 LYS 145 146 146 LYS LYS L . n 
B 2 146 VAL 146 147 147 VAL VAL L . n 
B 2 147 GLN 147 148 148 GLN GLN L . n 
B 2 148 TRP 148 149 149 TRP TRP L . n 
B 2 149 LYS 149 150 150 LYS LYS L . n 
B 2 150 VAL 150 151 151 VAL VAL L . n 
B 2 151 ASP 151 152 152 ASP ASP L . n 
B 2 152 ASN 152 153 153 ASN ASN L . n 
B 2 153 ALA 153 154 154 ALA ALA L . n 
B 2 154 LEU 154 155 155 LEU LEU L . n 
B 2 155 GLN 155 156 156 GLN GLN L . n 
B 2 156 SER 156 157 157 SER SER L . n 
B 2 157 GLY 157 158 158 GLY GLY L . n 
B 2 158 ASN 158 159 159 ASN ASN L . n 
B 2 159 SER 159 160 160 SER SER L . n 
B 2 160 GLN 160 161 161 GLN GLN L . n 
B 2 161 GLU 161 162 162 GLU GLU L . n 
B 2 162 SER 162 163 163 SER SER L . n 
B 2 163 VAL 163 164 164 VAL VAL L . n 
B 2 164 THR 164 165 165 THR THR L . n 
B 2 165 GLU 165 166 166 GLU GLU L . n 
B 2 166 GLN 166 167 167 GLN GLN L . n 
B 2 167 ASP 167 168 168 ASP ASP L . n 
B 2 168 SER 168 169 169 SER SER L . n 
B 2 169 LYS 169 170 170 LYS LYS L . n 
B 2 170 ASP 170 171 171 ASP ASP L . n 
B 2 171 SER 171 172 172 SER SER L . n 
B 2 172 THR 172 173 173 THR THR L . n 
B 2 173 TYR 173 174 174 TYR TYR L . n 
B 2 174 SER 174 175 175 SER SER L . n 
B 2 175 LEU 175 176 176 LEU LEU L . n 
B 2 176 SER 176 177 177 SER SER L . n 
B 2 177 SER 177 178 178 SER SER L . n 
B 2 178 THR 178 179 179 THR THR L . n 
B 2 179 LEU 179 180 180 LEU LEU L . n 
B 2 180 THR 180 181 181 THR THR L . n 
B 2 181 LEU 181 182 182 LEU LEU L . n 
B 2 182 SER 182 183 183 SER SER L . n 
B 2 183 LYS 183 184 184 LYS LYS L . n 
B 2 184 ALA 184 185 185 ALA ALA L . n 
B 2 185 ASP 185 186 186 ASP ASP L . n 
B 2 186 TYR 186 187 187 TYR TYR L . n 
B 2 187 GLU 187 188 188 GLU GLU L . n 
B 2 188 LYS 188 189 189 LYS LYS L . n 
B 2 189 HIS 189 190 190 HIS HIS L . n 
B 2 190 LYS 190 191 191 LYS LYS L . n 
B 2 191 VAL 191 192 192 VAL VAL L . n 
B 2 192 TYR 192 193 193 TYR TYR L . n 
B 2 193 ALA 193 194 194 ALA ALA L . n 
B 2 194 CYS 194 195 195 CYS CYS L . n 
B 2 195 GLU 195 196 196 GLU GLU L . n 
B 2 196 VAL 196 197 197 VAL VAL L . n 
B 2 197 THR 197 198 198 THR THR L . n 
B 2 198 HIS 198 199 199 HIS HIS L . n 
B 2 199 GLN 199 200 200 GLN GLN L . n 
B 2 200 GLY 200 201 201 GLY GLY L . n 
B 2 201 LEU 201 202 202 LEU LEU L . n 
B 2 202 SER 202 203 203 SER SER L . n 
B 2 203 SER 203 204 204 SER SER L . n 
B 2 204 PRO 204 205 205 PRO PRO L . n 
B 2 205 VAL 205 206 206 VAL VAL L . n 
B 2 206 THR 206 207 207 THR THR L . n 
B 2 207 LYS 207 208 208 LYS LYS L . n 
B 2 208 SER 208 209 209 SER SER L . n 
B 2 209 PHE 209 210 210 PHE PHE L . n 
B 2 210 ASN 210 211 211 ASN ASN L . n 
B 2 211 ARG 211 212 212 ARG ARG L . n 
B 2 212 GLY 212 213 213 GLY GLY L . n 
B 2 213 GLU 213 214 214 GLU GLU L . n 
B 2 214 CYS 214 215 ?   ?   ?   L . n 
C 3 1   GLN 1   1   1   GLN GLN H . n 
C 3 2   VAL 2   2   2   VAL VAL H . n 
C 3 3   GLN 3   3   3   GLN GLN H . n 
C 3 4   LEU 4   4   4   LEU LEU H . n 
C 3 5   VAL 5   5   5   VAL VAL H . n 
C 3 6   GLU 6   6   6   GLU GLU H . n 
C 3 7   SER 7   7   7   SER SER H . n 
C 3 8   GLY 8   8   8   GLY GLY H . n 
C 3 9   ALA 9   9   9   ALA ALA H . n 
C 3 10  GLU 10  10  10  GLU GLU H . n 
C 3 11  ALA 11  11  11  ALA ALA H . n 
C 3 12  LYS 12  12  12  LYS LYS H . n 
C 3 13  LYS 13  13  13  LYS LYS H . n 
C 3 14  PRO 14  14  14  PRO PRO H . n 
C 3 15  GLY 15  15  15  GLY GLY H . n 
C 3 16  SER 16  16  16  SER SER H . n 
C 3 17  SER 17  17  17  SER SER H . n 
C 3 18  VAL 18  18  18  VAL VAL H . n 
C 3 19  LYS 19  19  19  LYS LYS H . n 
C 3 20  VAL 20  20  20  VAL VAL H . n 
C 3 21  SER 21  21  21  SER SER H . n 
C 3 22  CYS 22  22  22  CYS CYS H . n 
C 3 23  LYS 23  23  23  LYS LYS H . n 
C 3 24  ILE 24  24  24  ILE ILE H . n 
C 3 25  SER 25  25  25  SER SER H . n 
C 3 26  GLY 26  26  26  GLY GLY H . n 
C 3 27  GLY 27  27  27  GLY GLY H . n 
C 3 28  THR 28  28  28  THR THR H . n 
C 3 29  LEU 29  29  29  LEU LEU H . n 
C 3 30  ASN 30  30  30  ASN ASN H . n 
C 3 31  ASP 31  31  31  ASP ASP H . n 
C 3 32  TYR 32  32  32  TYR TYR H . n 
C 3 33  PRO 33  33  33  PRO PRO H . n 
C 3 34  ILE 34  34  34  ILE ILE H . n 
C 3 35  ARG 35  35  35  ARG ARG H . n 
C 3 36  TRP 36  36  36  TRP TRP H . n 
C 3 37  VAL 37  37  37  VAL VAL H . n 
C 3 38  ARG 38  38  38  ARG ARG H . n 
C 3 39  GLN 39  39  39  GLN GLN H . n 
C 3 40  ALA 40  40  40  ALA ALA H . n 
C 3 41  PRO 41  41  41  PRO PRO H . n 
C 3 42  GLY 42  42  42  GLY GLY H . n 
C 3 43  GLN 43  43  43  GLN GLN H . n 
C 3 44  GLY 44  44  44  GLY GLY H . n 
C 3 45  LEU 45  45  45  LEU LEU H . n 
C 3 46  GLU 46  46  46  GLU GLU H . n 
C 3 47  TRP 47  47  47  TRP TRP H . n 
C 3 48  MET 48  48  48  MET MET H . n 
C 3 49  GLY 49  49  49  GLY GLY H . n 
C 3 50  GLY 50  50  50  GLY GLY H . n 
C 3 51  ILE 51  51  51  ILE ILE H . n 
C 3 52  ILE 52  52  52  ILE ILE H . n 
C 3 53  PRO 53  53  53  PRO PRO H . n 
C 3 54  ILE 54  54  54  ILE ILE H . n 
C 3 55  LEU 55  55  55  LEU LEU H . n 
C 3 56  GLY 56  56  56  GLY GLY H . n 
C 3 57  THR 57  57  57  THR THR H . n 
C 3 58  SER 58  58  58  SER SER H . n 
C 3 59  TYR 59  59  59  TYR TYR H . n 
C 3 60  GLU 60  60  60  GLU GLU H . n 
C 3 61  THR 61  61  61  THR THR H . n 
C 3 62  GLN 62  62  62  GLN GLN H . n 
C 3 63  LYS 63  63  63  LYS LYS H . n 
C 3 64  PHE 64  64  64  PHE PHE H . n 
C 3 65  GLN 65  65  65  GLN GLN H . n 
C 3 66  GLY 66  66  66  GLY GLY H . n 
C 3 67  ARG 67  67  67  ARG ARG H . n 
C 3 68  LEU 68  68  68  LEU LEU H . n 
C 3 69  THR 69  69  69  THR THR H . n 
C 3 70  LEU 70  70  70  LEU LEU H . n 
C 3 71  THR 71  71  71  THR THR H . n 
C 3 72  ALA 72  72  72  ALA ALA H . n 
C 3 73  ASP 73  73  73  ASP ASP H . n 
C 3 74  GLU 74  74  74  GLU GLU H . n 
C 3 75  LEU 75  75  75  LEU LEU H . n 
C 3 76  THR 76  76  76  THR THR H . n 
C 3 77  SER 77  77  77  SER SER H . n 
C 3 78  THR 78  78  78  THR THR H . n 
C 3 79  VAL 79  79  79  VAL VAL H . n 
C 3 80  TYR 80  80  80  TYR TYR H . n 
C 3 81  MET 81  81  81  MET MET H . n 
C 3 82  GLU 82  82  82  GLU GLU H . n 
C 3 83  LEU 83  83  83  LEU LEU H . n 
C 3 84  ARG 84  84  84  ARG ARG H . n 
C 3 85  TYR 85  85  85  TYR TYR H . n 
C 3 86  LEU 86  86  86  LEU LEU H . n 
C 3 87  THR 87  87  87  THR THR H . n 
C 3 88  SER 88  88  88  SER SER H . n 
C 3 89  GLU 89  89  89  GLU GLU H . n 
C 3 90  ASP 90  90  90  ASP ASP H . n 
C 3 91  ALA 91  91  91  ALA ALA H . n 
C 3 92  ALA 92  92  92  ALA ALA H . n 
C 3 93  VAL 93  93  93  VAL VAL H . n 
C 3 94  TYR 94  94  94  TYR TYR H . n 
C 3 95  PHE 95  95  95  PHE PHE H . n 
C 3 96  CYS 96  96  96  CYS CYS H . n 
C 3 97  ALA 97  97  97  ALA ALA H . n 
C 3 98  THR 98  98  98  THR THR H . n 
C 3 99  MET 99  99  99  MET MET H . n 
C 3 100 THR 100 100 100 THR THR H . n 
C 3 101 SER 101 101 101 SER SER H . n 
C 3 102 PRO 102 102 102 PRO PRO H . n 
C 3 103 VAL 103 103 103 VAL VAL H . n 
C 3 104 PHE 104 104 104 PHE PHE H . n 
C 3 105 ILE 105 105 105 ILE ILE H . n 
C 3 106 ASP 106 106 106 ASP ASP H . n 
C 3 107 ALA 107 107 107 ALA ALA H . n 
C 3 108 LEU 108 108 108 LEU LEU H . n 
C 3 109 ASP 109 109 109 ASP ASP H . n 
C 3 110 VAL 110 110 110 VAL VAL H . n 
C 3 111 TRP 111 111 111 TRP TRP H . n 
C 3 112 GLY 112 112 112 GLY GLY H . n 
C 3 113 GLN 113 113 113 GLN GLN H . n 
C 3 114 GLY 114 114 114 GLY GLY H . n 
C 3 115 THR 115 115 115 THR THR H . n 
C 3 116 ARG 116 116 116 ARG ARG H . n 
C 3 117 VAL 117 117 117 VAL VAL H . n 
C 3 118 THR 118 118 118 THR THR H . n 
C 3 119 VAL 119 119 119 VAL VAL H . n 
C 3 120 SER 120 120 120 SER SER H . n 
C 3 121 SER 121 121 121 SER SER H . n 
C 3 122 ALA 122 122 122 ALA ALA H . n 
C 3 123 SER 123 123 123 SER SER H . n 
C 3 124 THR 124 124 124 THR THR H . n 
C 3 125 LYS 125 125 125 LYS LYS H . n 
C 3 126 GLY 126 126 126 GLY GLY H . n 
C 3 127 PRO 127 127 127 PRO PRO H . n 
C 3 128 SER 128 128 128 SER SER H . n 
C 3 129 VAL 129 129 129 VAL VAL H . n 
C 3 130 PHE 130 130 130 PHE PHE H . n 
C 3 131 PRO 131 131 131 PRO PRO H . n 
C 3 132 LEU 132 132 132 LEU LEU H . n 
C 3 133 ALA 133 133 133 ALA ALA H . n 
C 3 134 PRO 134 134 134 PRO PRO H . n 
C 3 135 SER 135 135 135 SER ALA H . n 
C 3 136 SER 136 136 136 SER ALA H . n 
C 3 137 LYS 137 137 137 LYS ALA H . n 
C 3 138 SER 138 138 ?   ?   ?   H . n 
C 3 139 THR 139 139 ?   ?   ?   H . n 
C 3 140 SER 140 140 ?   ?   ?   H . n 
C 3 141 GLY 141 141 ?   ?   ?   H . n 
C 3 142 GLY 142 142 142 GLY GLY H . n 
C 3 143 THR 143 143 143 THR THR H . n 
C 3 144 ALA 144 144 144 ALA ALA H . n 
C 3 145 ALA 145 145 145 ALA ALA H . n 
C 3 146 LEU 146 146 146 LEU LEU H . n 
C 3 147 GLY 147 147 147 GLY GLY H . n 
C 3 148 CYS 148 148 148 CYS CYS H . n 
C 3 149 LEU 149 149 149 LEU LEU H . n 
C 3 150 VAL 150 150 150 VAL VAL H . n 
C 3 151 LYS 151 151 151 LYS LYS H . n 
C 3 152 ASP 152 152 152 ASP ASP H . n 
C 3 153 TYR 153 153 153 TYR TYR H . n 
C 3 154 PHE 154 154 154 PHE PHE H . n 
C 3 155 PRO 155 155 155 PRO PRO H . n 
C 3 156 GLU 156 156 156 GLU GLU H . n 
C 3 157 PRO 157 157 157 PRO PRO H . n 
C 3 158 VAL 158 158 158 VAL VAL H . n 
C 3 159 THR 159 159 159 THR THR H . n 
C 3 160 VAL 160 160 160 VAL VAL H . n 
C 3 161 SER 161 161 161 SER SER H . n 
C 3 162 TRP 162 162 162 TRP TRP H . n 
C 3 163 ASN 163 163 163 ASN ASN H . n 
C 3 164 SER 164 164 164 SER SER H . n 
C 3 165 GLY 165 165 165 GLY GLY H . n 
C 3 166 ALA 166 166 166 ALA ALA H . n 
C 3 167 LEU 167 167 167 LEU LEU H . n 
C 3 168 THR 168 168 168 THR THR H . n 
C 3 169 SER 169 169 169 SER SER H . n 
C 3 170 GLY 170 170 170 GLY GLY H . n 
C 3 171 VAL 171 171 171 VAL VAL H . n 
C 3 172 HIS 172 172 172 HIS HIS H . n 
C 3 173 THR 173 173 173 THR THR H . n 
C 3 174 PHE 174 174 174 PHE PHE H . n 
C 3 175 PRO 175 175 175 PRO PRO H . n 
C 3 176 ALA 176 176 176 ALA ALA H . n 
C 3 177 VAL 177 177 177 VAL VAL H . n 
C 3 178 LEU 178 178 178 LEU LEU H . n 
C 3 179 GLN 179 179 179 GLN GLN H . n 
C 3 180 SER 180 180 180 SER SER H . n 
C 3 181 SER 181 181 181 SER SER H . n 
C 3 182 GLY 182 182 182 GLY GLY H . n 
C 3 183 LEU 183 183 183 LEU LEU H . n 
C 3 184 TYR 184 184 184 TYR TYR H . n 
C 3 185 SER 185 185 185 SER SER H . n 
C 3 186 LEU 186 186 186 LEU LEU H . n 
C 3 187 SER 187 187 187 SER SER H . n 
C 3 188 SER 188 188 188 SER SER H . n 
C 3 189 VAL 189 189 189 VAL VAL H . n 
C 3 190 VAL 190 190 190 VAL VAL H . n 
C 3 191 THR 191 191 191 THR THR H . n 
C 3 192 VAL 192 192 192 VAL VAL H . n 
C 3 193 PRO 193 193 193 PRO PRO H . n 
C 3 194 SER 194 194 194 SER SER H . n 
C 3 195 SER 195 195 195 SER SER H . n 
C 3 196 SER 196 196 196 SER SER H . n 
C 3 197 LEU 197 197 197 LEU LEU H . n 
C 3 198 GLY 198 198 198 GLY GLY H . n 
C 3 199 THR 199 199 199 THR THR H . n 
C 3 200 GLN 200 200 200 GLN GLN H . n 
C 3 201 THR 201 201 201 THR THR H . n 
C 3 202 TYR 202 202 202 TYR TYR H . n 
C 3 203 ILE 203 203 203 ILE ILE H . n 
C 3 204 CYS 204 204 204 CYS CYS H . n 
C 3 205 ASN 205 205 205 ASN ASN H . n 
C 3 206 VAL 206 206 206 VAL VAL H . n 
C 3 207 ASN 207 207 207 ASN ASN H . n 
C 3 208 HIS 208 208 208 HIS HIS H . n 
C 3 209 LYS 209 209 209 LYS LYS H . n 
C 3 210 PRO 210 210 210 PRO PRO H . n 
C 3 211 SER 211 211 211 SER SER H . n 
C 3 212 ASN 212 212 212 ASN ASN H . n 
C 3 213 THR 213 213 213 THR THR H . n 
C 3 214 LYS 214 214 214 LYS LYS H . n 
C 3 215 VAL 215 215 215 VAL VAL H . n 
C 3 216 ASP 216 216 216 ASP ASP H . n 
C 3 217 LYS 217 217 217 LYS LYS H . n 
C 3 218 ARG 218 218 218 ARG ARG H . n 
C 3 219 VAL 219 219 219 VAL VAL H . n 
C 3 220 GLU 220 220 220 GLU GLU H . n 
C 3 221 PRO 221 221 221 PRO PRO H . n 
C 3 222 LYS 222 222 ?   ?   ?   H . n 
C 3 223 SER 223 223 ?   ?   ?   H . n 
C 3 224 CYS 224 224 ?   ?   ?   H . n 
C 3 225 ASP 225 225 ?   ?   ?   H . n 
C 3 226 LYS 226 226 ?   ?   ?   H . n 
C 3 227 GLY 227 227 ?   ?   ?   H . n 
C 3 228 SER 228 228 ?   ?   ?   H . n 
C 3 229 GLU 229 229 ?   ?   ?   H . n 
C 3 230 ASN 230 230 ?   ?   ?   H . n 
C 3 231 LEU 231 231 ?   ?   ?   H . n 
C 3 232 TYR 232 232 ?   ?   ?   H . n 
C 3 233 PHE 233 233 ?   ?   ?   H . n 
C 3 234 GLN 234 234 ?   ?   ?   H . n 
C 3 235 GLY 235 235 ?   ?   ?   H . n 
C 3 236 SER 236 236 ?   ?   ?   H . n 
C 3 237 HIS 237 237 ?   ?   ?   H . n 
C 3 238 HIS 238 238 ?   ?   ?   H . n 
C 3 239 HIS 239 239 ?   ?   ?   H . n 
C 3 240 HIS 240 240 ?   ?   ?   H . n 
C 3 241 HIS 241 241 ?   ?   ?   H . n 
C 3 242 HIS 242 242 ?   ?   ?   H . n 
D 4 1   PHE 1   137 137 PHE PHE B . n 
D 4 2   LEU 2   138 138 LEU LEU B . n 
D 4 3   GLY 3   139 139 GLY GLY B . n 
D 4 4   PHE 4   140 140 PHE PHE B . n 
D 4 5   LEU 5   141 141 LEU LEU B . n 
D 4 6   LEU 6   142 142 LEU LEU B . n 
D 4 7   GLY 7   143 143 GLY GLY B . n 
D 4 8   VAL 8   144 144 VAL VAL B . n 
D 4 9   GLY 9   145 145 GLY GLY B . n 
D 4 10  SER 10  146 146 SER SER B . n 
D 4 11  ALA 11  147 147 ALA ALA B . n 
D 4 12  ILE 12  148 148 ILE ILE B . n 
D 4 13  ALA 13  149 149 ALA ALA B . n 
D 4 14  SER 14  150 150 SER SER B . n 
D 4 15  GLY 15  151 151 GLY GLY B . n 
D 4 16  VAL 16  152 152 VAL VAL B . n 
D 4 17  ALA 17  153 153 ALA ALA B . n 
D 4 18  VAL 18  154 154 VAL VAL B . n 
D 4 19  CYS 19  155 155 CYS CYS B . n 
D 4 20  LYS 20  156 156 LYS LYS B . n 
D 4 21  VAL 21  157 157 VAL VAL B . n 
D 4 22  LEU 22  158 158 LEU LEU B . n 
D 4 23  HIS 23  159 159 HIS HIS B . n 
D 4 24  LEU 24  160 160 LEU LEU B . n 
D 4 25  GLU 25  161 161 GLU GLU B . n 
D 4 26  GLY 26  162 162 GLY GLY B . n 
D 4 27  GLU 27  163 163 GLU GLU B . n 
D 4 28  VAL 28  164 164 VAL VAL B . n 
D 4 29  ASN 29  165 165 ASN ASN B . n 
D 4 30  LYS 30  166 166 LYS LYS B . n 
D 4 31  ILE 31  167 167 ILE ILE B . n 
D 4 32  LYS 32  168 168 LYS LYS B . n 
D 4 33  SER 33  169 169 SER SER B . n 
D 4 34  ALA 34  170 170 ALA ALA B . n 
D 4 35  LEU 35  171 171 LEU LEU B . n 
D 4 36  LEU 36  172 172 LEU LEU B . n 
D 4 37  SER 37  173 173 SER SER B . n 
D 4 38  THR 38  174 174 THR THR B . n 
D 4 39  ASN 39  175 175 ASN ASN B . n 
D 4 40  LYS 40  176 176 LYS LYS B . n 
D 4 41  ALA 41  177 177 ALA ALA B . n 
D 4 42  VAL 42  178 178 VAL VAL B . n 
D 4 43  VAL 43  179 179 VAL VAL B . n 
D 4 44  SER 44  180 180 SER SER B . n 
D 4 45  LEU 45  181 181 LEU LEU B . n 
D 4 46  SER 46  182 182 SER SER B . n 
D 4 47  ASN 47  183 183 ASN ASN B . n 
D 4 48  GLY 48  184 184 GLY GLY B . n 
D 4 49  VAL 49  185 185 VAL VAL B . n 
D 4 50  SER 50  186 186 SER SER B . n 
D 4 51  VAL 51  187 187 VAL VAL B . n 
D 4 52  LEU 52  188 188 LEU LEU B . n 
D 4 53  THR 53  189 189 THR THR B . n 
D 4 54  PHE 54  190 190 PHE PHE B . n 
D 4 55  LYS 55  191 191 LYS LYS B . n 
D 4 56  VAL 56  192 192 VAL VAL B . n 
D 4 57  LEU 57  193 193 LEU LEU B . n 
D 4 58  ASP 58  194 194 ASP ASP B . n 
D 4 59  LEU 59  195 195 LEU LEU B . n 
D 4 60  LYS 60  196 196 LYS LYS B . n 
D 4 61  ASN 61  197 197 ASN ASN B . n 
D 4 62  TYR 62  198 198 TYR TYR B . n 
D 4 63  ILE 63  199 199 ILE ILE B . n 
D 4 64  ASP 64  200 200 ASP ASP B . n 
D 4 65  LYS 65  201 201 LYS LYS B . n 
D 4 66  GLN 66  202 202 GLN GLN B . n 
D 4 67  LEU 67  203 203 LEU LEU B . n 
D 4 68  LEU 68  204 204 LEU LEU B . n 
D 4 69  PRO 69  205 205 PRO PRO B . n 
D 4 70  ILE 70  206 206 ILE ILE B . n 
D 4 71  LEU 71  207 207 LEU LEU B . n 
D 4 72  ASN 72  208 208 ASN ASN B . n 
D 4 73  LYS 73  209 209 LYS LYS B . n 
D 4 74  GLN 74  210 210 GLN GLN B . n 
D 4 75  SER 75  211 211 SER SER B . n 
D 4 76  CYS 76  212 212 CYS CYS B . n 
D 4 77  SER 77  213 213 SER SER B . n 
D 4 78  ILE 78  214 214 ILE ILE B . n 
D 4 79  SER 79  215 215 SER SER B . n 
D 4 80  ASN 80  216 216 ASN ASN B . n 
D 4 81  ILE 81  217 217 ILE ILE B . n 
D 4 82  GLU 82  218 218 GLU GLU B . n 
D 4 83  THR 83  219 219 THR THR B . n 
D 4 84  VAL 84  220 220 VAL VAL B . n 
D 4 85  ILE 85  221 221 ILE ILE B . n 
D 4 86  GLU 86  222 222 GLU GLU B . n 
D 4 87  PHE 87  223 223 PHE PHE B . n 
D 4 88  GLN 88  224 224 GLN GLN B . n 
D 4 89  GLN 89  225 225 GLN GLN B . n 
D 4 90  LYS 90  226 226 LYS LYS B . n 
D 4 91  ASN 91  227 227 ASN ASN B . n 
D 4 92  ASN 92  228 228 ASN ASN B . n 
D 4 93  ARG 93  229 229 ARG ARG B . n 
D 4 94  LEU 94  230 230 LEU LEU B . n 
D 4 95  LEU 95  231 231 LEU LEU B . n 
D 4 96  GLU 96  232 232 GLU GLU B . n 
D 4 97  ILE 97  233 233 ILE ILE B . n 
D 4 98  THR 98  234 234 THR THR B . n 
D 4 99  ARG 99  235 235 ARG ARG B . n 
D 4 100 GLU 100 236 236 GLU GLU B . n 
D 4 101 PHE 101 237 237 PHE PHE B . n 
D 4 102 SER 102 238 238 SER SER B . n 
D 4 103 VAL 103 239 239 VAL VAL B . n 
D 4 104 ASN 104 240 240 ASN ASN B . n 
D 4 105 ALA 105 241 241 ALA ALA B . n 
D 4 106 GLY 106 242 242 GLY GLY B . n 
D 4 107 VAL 107 243 243 VAL VAL B . n 
D 4 108 THR 108 244 244 THR THR B . n 
D 4 109 THR 109 245 245 THR THR B . n 
D 4 110 PRO 110 246 246 PRO PRO B . n 
D 4 111 VAL 111 247 247 VAL VAL B . n 
D 4 112 SER 112 248 248 SER SER B . n 
D 4 113 THR 113 249 249 THR THR B . n 
D 4 114 TYR 114 250 250 TYR TYR B . n 
D 4 115 MET 115 251 251 MET MET B . n 
D 4 116 LEU 116 252 252 LEU LEU B . n 
D 4 117 THR 117 253 253 THR THR B . n 
D 4 118 ASN 118 254 254 ASN ASN B . n 
D 4 119 SER 119 255 255 SER SER B . n 
D 4 120 GLU 120 256 256 GLU GLU B . n 
D 4 121 LEU 121 257 257 LEU LEU B . n 
D 4 122 LEU 122 258 258 LEU LEU B . n 
D 4 123 SER 123 259 259 SER SER B . n 
D 4 124 LEU 124 260 260 LEU LEU B . n 
D 4 125 ILE 125 261 261 ILE ILE B . n 
D 4 126 ASN 126 262 262 ASN ASN B . n 
D 4 127 ASP 127 263 263 ASP ASP B . n 
D 4 128 MET 128 264 264 MET MET B . n 
D 4 129 PRO 129 265 265 PRO PRO B . n 
D 4 130 ILE 130 266 266 ILE ILE B . n 
D 4 131 THR 131 267 267 THR THR B . n 
D 4 132 ASN 132 268 268 ASN ASN B . n 
D 4 133 ASP 133 269 269 ASP ASP B . n 
D 4 134 GLN 134 270 270 GLN GLN B . n 
D 4 135 LYS 135 271 271 LYS LYS B . n 
D 4 136 LYS 136 272 272 LYS LYS B . n 
D 4 137 LEU 137 273 273 LEU LEU B . n 
D 4 138 MET 138 274 274 MET MET B . n 
D 4 139 SER 139 275 275 SER SER B . n 
D 4 140 ASN 140 276 276 ASN ASN B . n 
D 4 141 ASN 141 277 277 ASN ASN B . n 
D 4 142 VAL 142 278 278 VAL VAL B . n 
D 4 143 GLN 143 279 279 GLN GLN B . n 
D 4 144 ILE 144 280 280 ILE ILE B . n 
D 4 145 VAL 145 281 281 VAL VAL B . n 
D 4 146 ARG 146 282 282 ARG ARG B . n 
D 4 147 GLN 147 283 283 GLN GLN B . n 
D 4 148 GLN 148 284 284 GLN GLN B . n 
D 4 149 SER 149 285 285 SER SER B . n 
D 4 150 TYR 150 286 286 TYR TYR B . n 
D 4 151 SER 151 287 287 SER SER B . n 
D 4 152 ILE 152 288 288 ILE ILE B . n 
D 4 153 MET 153 289 289 MET MET B . n 
D 4 154 CYS 154 290 290 CYS CYS B . n 
D 4 155 ILE 155 291 291 ILE ILE B . n 
D 4 156 ILE 156 292 292 ILE ILE B . n 
D 4 157 LYS 157 293 293 LYS LYS B . n 
D 4 158 GLU 158 294 294 GLU GLU B . n 
D 4 159 GLU 159 295 295 GLU GLU B . n 
D 4 160 VAL 160 296 296 VAL VAL B . n 
D 4 161 LEU 161 297 297 LEU LEU B . n 
D 4 162 ALA 162 298 298 ALA ALA B . n 
D 4 163 TYR 163 299 299 TYR TYR B . n 
D 4 164 VAL 164 300 300 VAL VAL B . n 
D 4 165 VAL 165 301 301 VAL VAL B . n 
D 4 166 GLN 166 302 302 GLN GLN B . n 
D 4 167 LEU 167 303 303 LEU LEU B . n 
D 4 168 PRO 168 304 304 PRO PRO B . n 
D 4 169 LEU 169 305 305 LEU LEU B . n 
D 4 170 TYR 170 306 306 TYR TYR B . n 
D 4 171 GLY 171 307 307 GLY GLY B . n 
D 4 172 VAL 172 308 308 VAL VAL B . n 
D 4 173 ILE 173 309 309 ILE ILE B . n 
D 4 174 ASP 174 310 310 ASP ASP B . n 
D 4 175 THR 175 311 311 THR THR B . n 
D 4 176 PRO 176 312 312 PRO PRO B . n 
D 4 177 CYS 177 313 313 CYS CYS B . n 
D 4 178 TRP 178 314 314 TRP TRP B . n 
D 4 179 LYS 179 315 315 LYS LYS B . n 
D 4 180 LEU 180 316 316 LEU LEU B . n 
D 4 181 HIS 181 317 317 HIS HIS B . n 
D 4 182 THR 182 318 318 THR THR B . n 
D 4 183 SER 183 319 319 SER SER B . n 
D 4 184 PRO 184 320 320 PRO PRO B . n 
D 4 185 LEU 185 321 321 LEU LEU B . n 
D 4 186 CYS 186 322 322 CYS CYS B . n 
D 4 187 THR 187 323 323 THR THR B . n 
D 4 188 THR 188 324 324 THR THR B . n 
D 4 189 ASN 189 325 325 ASN ASN B . n 
D 4 190 THR 190 326 326 THR THR B . n 
D 4 191 LYS 191 327 327 LYS LYS B . n 
D 4 192 GLU 192 328 328 GLU GLU B . n 
D 4 193 GLY 193 329 329 GLY GLY B . n 
D 4 194 SER 194 330 330 SER SER B . n 
D 4 195 ASN 195 331 331 ASN ASN B . n 
D 4 196 ILE 196 332 332 ILE ILE B . n 
D 4 197 CYS 197 333 333 CYS CYS B . n 
D 4 198 LEU 198 334 334 LEU LEU B . n 
D 4 199 THR 199 335 335 THR THR B . n 
D 4 200 ARG 200 336 336 ARG ARG B . n 
D 4 201 THR 201 337 337 THR THR B . n 
D 4 202 ASP 202 338 338 ASP ASP B . n 
D 4 203 ARG 203 339 339 ARG ARG B . n 
D 4 204 GLY 204 340 340 GLY GLY B . n 
D 4 205 TRP 205 341 341 TRP TRP B . n 
D 4 206 TYR 206 342 342 TYR TYR B . n 
D 4 207 CYS 207 343 343 CYS CYS B . n 
D 4 208 ASP 208 344 344 ASP ASP B . n 
D 4 209 ASN 209 345 345 ASN ASN B . n 
D 4 210 ALA 210 346 346 ALA ALA B . n 
D 4 211 GLY 211 347 347 GLY GLY B . n 
D 4 212 SER 212 348 348 SER SER B . n 
D 4 213 VAL 213 349 349 VAL VAL B . n 
D 4 214 SER 214 350 350 SER SER B . n 
D 4 215 PHE 215 351 351 PHE PHE B . n 
D 4 216 PHE 216 352 352 PHE PHE B . n 
D 4 217 PRO 217 353 353 PRO PRO B . n 
D 4 218 GLN 218 354 354 GLN GLN B . n 
D 4 219 ALA 219 355 355 ALA ALA B . n 
D 4 220 GLU 220 356 356 GLU GLU B . n 
D 4 221 THR 221 357 357 THR THR B . n 
D 4 222 CYS 222 358 358 CYS CYS B . n 
D 4 223 LYS 223 359 359 LYS LYS B . n 
D 4 224 VAL 224 360 360 VAL VAL B . n 
D 4 225 GLN 225 361 361 GLN GLN B . n 
D 4 226 SER 226 362 362 SER SER B . n 
D 4 227 ASN 227 363 363 ASN ASN B . n 
D 4 228 ARG 228 364 364 ARG ARG B . n 
D 4 229 VAL 229 365 365 VAL VAL B . n 
D 4 230 PHE 230 366 366 PHE PHE B . n 
D 4 231 CYS 231 367 367 CYS CYS B . n 
D 4 232 ASP 232 368 368 ASP ASP B . n 
D 4 233 THR 233 369 369 THR THR B . n 
D 4 234 MET 234 370 370 MET MET B . n 
D 4 235 ASN 235 371 371 ASN ASN B . n 
D 4 236 SER 236 372 372 SER SER B . n 
D 4 237 LEU 237 373 373 LEU LEU B . n 
D 4 238 THR 238 374 374 THR THR B . n 
D 4 239 LEU 239 375 375 LEU LEU B . n 
D 4 240 PRO 240 376 376 PRO PRO B . n 
D 4 241 SER 241 377 377 SER SER B . n 
D 4 242 GLU 242 378 378 GLU GLU B . n 
D 4 243 VAL 243 379 379 VAL VAL B . n 
D 4 244 ASN 244 380 380 ASN ASN B . n 
D 4 245 LEU 245 381 381 LEU LEU B . n 
D 4 246 CYS 246 382 382 CYS CYS B . n 
D 4 247 ASN 247 383 383 ASN ASN B . n 
D 4 248 VAL 248 384 384 VAL VAL B . n 
D 4 249 ASP 249 385 385 ASP ASP B . n 
D 4 250 ILE 250 386 386 ILE ILE B . n 
D 4 251 PHE 251 387 387 PHE PHE B . n 
D 4 252 ASN 252 388 388 ASN ASN B . n 
D 4 253 PRO 253 389 389 PRO PRO B . n 
D 4 254 LYS 254 390 390 LYS LYS B . n 
D 4 255 TYR 255 391 391 TYR TYR B . n 
D 4 256 ASP 256 392 392 ASP ASP B . n 
D 4 257 CYS 257 393 393 CYS CYS B . n 
D 4 258 LYS 258 394 394 LYS LYS B . n 
D 4 259 ILE 259 395 395 ILE ILE B . n 
D 4 260 MET 260 396 396 MET MET B . n 
D 4 261 THR 261 397 397 THR THR B . n 
D 4 262 SER 262 398 398 SER SER B . n 
D 4 263 LYS 263 399 399 LYS LYS B . n 
D 4 264 THR 264 400 400 THR THR B . n 
D 4 265 ASP 265 401 401 ASP ASP B . n 
D 4 266 VAL 266 402 402 VAL VAL B . n 
D 4 267 SER 267 403 403 SER SER B . n 
D 4 268 SER 268 404 404 SER SER B . n 
D 4 269 SER 269 405 405 SER SER B . n 
D 4 270 VAL 270 406 406 VAL VAL B . n 
D 4 271 ILE 271 407 407 ILE ILE B . n 
D 4 272 THR 272 408 408 THR THR B . n 
D 4 273 SER 273 409 409 SER SER B . n 
D 4 274 LEU 274 410 410 LEU LEU B . n 
D 4 275 GLY 275 411 411 GLY GLY B . n 
D 4 276 ALA 276 412 412 ALA ALA B . n 
D 4 277 ILE 277 413 413 ILE ILE B . n 
D 4 278 VAL 278 414 414 VAL VAL B . n 
D 4 279 SER 279 415 415 SER SER B . n 
D 4 280 CYS 280 416 416 CYS CYS B . n 
D 4 281 TYR 281 417 417 TYR TYR B . n 
D 4 282 GLY 282 418 418 GLY GLY B . n 
D 4 283 LYS 283 419 419 LYS LYS B . n 
D 4 284 THR 284 420 420 THR THR B . n 
D 4 285 LYS 285 421 421 LYS LYS B . n 
D 4 286 CYS 286 422 422 CYS CYS B . n 
D 4 287 THR 287 423 423 THR THR B . n 
D 4 288 ALA 288 424 424 ALA ALA B . n 
D 4 289 SER 289 425 425 SER SER B . n 
D 4 290 ASN 290 426 426 ASN ASN B . n 
D 4 291 LYS 291 427 427 LYS LYS B . n 
D 4 292 ASN 292 428 428 ASN ASN B . n 
D 4 293 ARG 293 429 429 ARG ARG B . n 
D 4 294 GLY 294 430 430 GLY GLY B . n 
D 4 295 ILE 295 431 431 ILE ILE B . n 
D 4 296 ILE 296 432 432 ILE ILE B . n 
D 4 297 LYS 297 433 433 LYS LYS B . n 
D 4 298 THR 298 434 434 THR THR B . n 
D 4 299 PHE 299 435 435 PHE PHE B . n 
D 4 300 SER 300 436 436 SER SER B . n 
D 4 301 ASN 301 437 437 ASN ASN B . n 
D 4 302 GLY 302 438 438 GLY GLY B . n 
D 4 303 CYS 303 439 439 CYS CYS B . n 
D 4 304 ASP 304 440 440 ASP ASP B . n 
D 4 305 TYR 305 441 441 TYR TYR B . n 
D 4 306 VAL 306 442 442 VAL VAL B . n 
D 4 307 SER 307 443 443 SER SER B . n 
D 4 308 ASN 308 444 444 ASN ASN B . n 
D 4 309 LYS 309 445 445 LYS LYS B . n 
D 4 310 GLY 310 446 446 GLY GLY B . n 
D 4 311 VAL 311 447 447 VAL VAL B . n 
D 4 312 ASP 312 448 448 ASP ASP B . n 
D 4 313 THR 313 449 449 THR THR B . n 
D 4 314 VAL 314 450 450 VAL VAL B . n 
D 4 315 SER 315 451 451 SER SER B . n 
D 4 316 VAL 316 452 452 VAL VAL B . n 
D 4 317 GLY 317 453 453 GLY GLY B . n 
D 4 318 ASN 318 454 454 ASN ASN B . n 
D 4 319 THR 319 455 455 THR THR B . n 
D 4 320 LEU 320 456 456 LEU LEU B . n 
D 4 321 TYR 321 457 457 TYR TYR B . n 
D 4 322 TYR 322 458 458 TYR TYR B . n 
D 4 323 VAL 323 459 459 VAL VAL B . n 
D 4 324 ASN 324 460 460 ASN ASN B . n 
D 4 325 LYS 325 461 461 LYS LYS B . n 
D 4 326 GLN 326 462 462 GLN GLN B . n 
D 4 327 GLU 327 463 463 GLU GLU B . n 
D 4 328 GLY 328 464 464 GLY GLY B . n 
D 4 329 LYS 329 465 465 LYS LYS B . n 
D 4 330 SER 330 466 466 SER SER B . n 
D 4 331 LEU 331 467 467 LEU LEU B . n 
D 4 332 TYR 332 468 468 TYR TYR B . n 
D 4 333 VAL 333 469 469 VAL VAL B . n 
D 4 334 LYS 334 470 470 LYS LYS B . n 
D 4 335 GLY 335 471 471 GLY GLY B . n 
D 4 336 GLU 336 472 472 GLU GLU B . n 
D 4 337 PRO 337 473 473 PRO PRO B . n 
D 4 338 ILE 338 474 474 ILE ILE B . n 
D 4 339 ILE 339 475 475 ILE ILE B . n 
D 4 340 ASN 340 476 476 ASN ASN B . n 
D 4 341 PHE 341 477 477 PHE PHE B . n 
D 4 342 TYR 342 478 478 TYR TYR B . n 
D 4 343 ASP 343 479 479 ASP ASP B . n 
D 4 344 PRO 344 480 480 PRO PRO B . n 
D 4 345 LEU 345 481 481 LEU LEU B . n 
D 4 346 VAL 346 482 482 VAL VAL B . n 
D 4 347 PHE 347 483 483 PHE PHE B . n 
D 4 348 PRO 348 484 484 PRO PRO B . n 
D 4 349 SER 349 485 485 SER SER B . n 
D 4 350 ASP 350 486 486 ASP ASP B . n 
D 4 351 GLU 351 487 487 GLU GLU B . n 
D 4 352 PHE 352 488 488 PHE PHE B . n 
D 4 353 ASP 353 489 489 ASP ASP B . n 
D 4 354 ALA 354 490 490 ALA ALA B . n 
D 4 355 SER 355 491 491 SER SER B . n 
D 4 356 ILE 356 492 492 ILE ILE B . n 
D 4 357 SER 357 493 493 SER SER B . n 
D 4 358 GLN 358 494 494 GLN GLN B . n 
D 4 359 VAL 359 495 495 VAL VAL B . n 
D 4 360 ASN 360 496 496 ASN ASN B . n 
D 4 361 GLU 361 497 497 GLU GLU B . n 
D 4 362 LYS 362 498 498 LYS LYS B . n 
D 4 363 ILE 363 499 499 ILE ILE B . n 
D 4 364 ASN 364 500 500 ASN ASN B . n 
D 4 365 GLN 365 501 501 GLN GLN B . n 
D 4 366 SER 366 502 502 SER SER B . n 
D 4 367 LEU 367 503 503 LEU LEU B . n 
D 4 368 ALA 368 504 504 ALA ALA B . n 
D 4 369 PHE 369 505 505 PHE PHE B . n 
D 4 370 ILE 370 506 506 ILE ILE B . n 
D 4 371 ARG 371 507 507 ARG ARG B . n 
D 4 372 LYS 372 508 508 LYS LYS B . n 
D 4 373 SER 373 509 509 SER SER B . n 
D 4 374 ASP 374 510 510 ASP ASP B . n 
D 4 375 GLU 375 511 511 GLU GLU B . n 
D 4 376 LEU 376 512 512 LEU LEU B . n 
D 4 377 LEU 377 513 513 LEU LEU B . n 
D 4 378 SER 378 514 514 SER SER B . n 
D 4 379 ALA 379 515 515 ALA ALA B . n 
D 4 380 ILE 380 516 516 ILE ILE B . n 
D 4 381 GLY 381 517 517 GLY GLY B . n 
D 4 382 GLY 382 518 518 GLY GLY B . n 
D 4 383 TYR 383 519 519 TYR TYR B . n 
D 4 384 ILE 384 520 520 ILE ILE B . n 
D 4 385 PRO 385 521 521 PRO PRO B . n 
D 4 386 GLU 386 522 522 GLU GLU B . n 
D 4 387 ALA 387 523 523 ALA ALA B . n 
D 4 388 PRO 388 524 524 PRO PRO B . n 
D 4 389 ARG 389 525 525 ARG ARG B . n 
D 4 390 ASP 390 526 526 ASP ASP B . n 
D 4 391 GLY 391 527 527 GLY GLY B . n 
D 4 392 GLN 392 528 528 GLN GLN B . n 
D 4 393 ALA 393 529 529 ALA ALA B . n 
D 4 394 TYR 394 530 530 TYR TYR B . n 
D 4 395 VAL 395 531 531 VAL VAL B . n 
D 4 396 ARG 396 532 532 ARG ARG B . n 
D 4 397 LYS 397 533 533 LYS LYS B . n 
D 4 398 ASP 398 534 534 ASP ASP B . n 
D 4 399 GLY 399 535 535 GLY GLY B . n 
D 4 400 GLU 400 536 536 GLU GLU B . n 
D 4 401 TRP 401 537 537 TRP TRP B . n 
D 4 402 VAL 402 538 538 VAL VAL B . n 
D 4 403 LEU 403 539 539 LEU LEU B . n 
D 4 404 LEU 404 540 540 LEU LEU B . n 
D 4 405 SER 405 541 541 SER SER B . n 
D 4 406 THR 406 542 542 THR THR B . n 
D 4 407 PHE 407 543 543 PHE PHE B . n 
D 4 408 LEU 408 544 544 LEU LEU B . n 
D 4 409 GLY 409 545 ?   ?   ?   B . n 
D 4 410 GLY 410 546 ?   ?   ?   B . n 
D 4 411 LEU 411 547 ?   ?   ?   B . n 
D 4 412 VAL 412 548 ?   ?   ?   B . n 
D 4 413 PRO 413 549 ?   ?   ?   B . n 
D 4 414 ARG 414 550 ?   ?   ?   B . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 L SER 115 ? OG  ? B SER 114 OG  
2  1 Y 1 L PRO 121 ? CG  ? B PRO 120 CG  
3  1 Y 1 L PRO 121 ? CD  ? B PRO 120 CD  
4  1 Y 1 L SER 122 ? OG  ? B SER 121 OG  
5  1 Y 1 L ASP 123 ? CG  ? B ASP 122 CG  
6  1 Y 1 L ASP 123 ? OD1 ? B ASP 122 OD1 
7  1 Y 1 L ASP 123 ? OD2 ? B ASP 122 OD2 
8  1 Y 1 L VAL 133 ? CG1 ? B VAL 132 CG1 
9  1 Y 1 L VAL 133 ? CG2 ? B VAL 132 CG2 
10 1 Y 1 L VAL 134 ? CG1 ? B VAL 133 CG1 
11 1 Y 1 L VAL 134 ? CG2 ? B VAL 133 CG2 
12 1 Y 1 L GLN 148 ? CG  ? B GLN 147 CG  
13 1 Y 1 L GLN 148 ? CD  ? B GLN 147 CD  
14 1 Y 1 L GLN 148 ? OE1 ? B GLN 147 OE1 
15 1 Y 1 L GLN 148 ? NE2 ? B GLN 147 NE2 
16 1 Y 1 L LYS 150 ? CG  ? B LYS 149 CG  
17 1 Y 1 L LYS 150 ? CD  ? B LYS 149 CD  
18 1 Y 1 L LYS 150 ? CE  ? B LYS 149 CE  
19 1 Y 1 L LYS 150 ? NZ  ? B LYS 149 NZ  
20 1 Y 1 L VAL 151 ? CG1 ? B VAL 150 CG1 
21 1 Y 1 L VAL 151 ? CG2 ? B VAL 150 CG2 
22 1 Y 1 L LEU 155 ? CG  ? B LEU 154 CG  
23 1 Y 1 L LEU 155 ? CD1 ? B LEU 154 CD1 
24 1 Y 1 L LEU 155 ? CD2 ? B LEU 154 CD2 
25 1 Y 1 L GLN 156 ? CG  ? B GLN 155 CG  
26 1 Y 1 L GLN 156 ? CD  ? B GLN 155 CD  
27 1 Y 1 L GLN 156 ? OE1 ? B GLN 155 OE1 
28 1 Y 1 L GLN 156 ? NE2 ? B GLN 155 NE2 
29 1 Y 1 L SER 157 ? OG  ? B SER 156 OG  
30 1 Y 1 L SER 160 ? OG  ? B SER 159 OG  
31 1 Y 1 L SER 163 ? OG  ? B SER 162 OG  
32 1 Y 1 L VAL 164 ? CG1 ? B VAL 163 CG1 
33 1 Y 1 L VAL 164 ? CG2 ? B VAL 163 CG2 
34 1 Y 1 L SER 169 ? OG  ? B SER 168 OG  
35 1 Y 1 L LYS 170 ? CG  ? B LYS 169 CG  
36 1 Y 1 L LYS 170 ? CD  ? B LYS 169 CD  
37 1 Y 1 L LYS 170 ? CE  ? B LYS 169 CE  
38 1 Y 1 L LYS 170 ? NZ  ? B LYS 169 NZ  
39 1 Y 1 L SER 175 ? OG  ? B SER 174 OG  
40 1 Y 1 L SER 177 ? OG  ? B SER 176 OG  
41 1 Y 1 L SER 178 ? OG  ? B SER 177 OG  
42 1 Y 1 L SER 183 ? OG  ? B SER 182 OG  
43 1 Y 1 L LYS 184 ? CG  ? B LYS 183 CG  
44 1 Y 1 L LYS 184 ? CD  ? B LYS 183 CD  
45 1 Y 1 L LYS 184 ? CE  ? B LYS 183 CE  
46 1 Y 1 L LYS 184 ? NZ  ? B LYS 183 NZ  
47 1 Y 1 L ASP 186 ? CG  ? B ASP 185 CG  
48 1 Y 1 L ASP 186 ? OD1 ? B ASP 185 OD1 
49 1 Y 1 L ASP 186 ? OD2 ? B ASP 185 OD2 
50 1 Y 1 L TYR 187 ? CG  ? B TYR 186 CG  
51 1 Y 1 L TYR 187 ? CD1 ? B TYR 186 CD1 
52 1 Y 1 L TYR 187 ? CD2 ? B TYR 186 CD2 
53 1 Y 1 L TYR 187 ? CE1 ? B TYR 186 CE1 
54 1 Y 1 L TYR 187 ? CE2 ? B TYR 186 CE2 
55 1 Y 1 L TYR 187 ? CZ  ? B TYR 186 CZ  
56 1 Y 1 L TYR 187 ? OH  ? B TYR 186 OH  
57 1 Y 1 L LYS 189 ? CG  ? B LYS 188 CG  
58 1 Y 1 L LYS 189 ? CD  ? B LYS 188 CD  
59 1 Y 1 L LYS 189 ? CE  ? B LYS 188 CE  
60 1 Y 1 L LYS 189 ? NZ  ? B LYS 188 NZ  
61 1 Y 1 L HIS 190 ? CG  ? B HIS 189 CG  
62 1 Y 1 L HIS 190 ? ND1 ? B HIS 189 ND1 
63 1 Y 1 L HIS 190 ? CD2 ? B HIS 189 CD2 
64 1 Y 1 L HIS 190 ? CE1 ? B HIS 189 CE1 
65 1 Y 1 L HIS 190 ? NE2 ? B HIS 189 NE2 
66 1 Y 1 L LYS 191 ? CG  ? B LYS 190 CG  
67 1 Y 1 L LYS 191 ? CD  ? B LYS 190 CD  
68 1 Y 1 L LYS 191 ? CE  ? B LYS 190 CE  
69 1 Y 1 L LYS 191 ? NZ  ? B LYS 190 NZ  
70 1 Y 1 L SER 209 ? OG  ? B SER 208 OG  
71 1 Y 1 L PHE 210 ? CG  ? B PHE 209 CG  
72 1 Y 1 L PHE 210 ? CD1 ? B PHE 209 CD1 
73 1 Y 1 L PHE 210 ? CD2 ? B PHE 209 CD2 
74 1 Y 1 L PHE 210 ? CE1 ? B PHE 209 CE1 
75 1 Y 1 L PHE 210 ? CE2 ? B PHE 209 CE2 
76 1 Y 1 L PHE 210 ? CZ  ? B PHE 209 CZ  
77 1 Y 1 L ASN 211 ? CG  ? B ASN 210 CG  
78 1 Y 1 L ASN 211 ? OD1 ? B ASN 210 OD1 
79 1 Y 1 L ASN 211 ? ND2 ? B ASN 210 ND2 
80 1 Y 1 L GLU 214 ? CG  ? B GLU 213 CG  
81 1 Y 1 L GLU 214 ? CD  ? B GLU 213 CD  
82 1 Y 1 L GLU 214 ? OE1 ? B GLU 213 OE1 
83 1 Y 1 L GLU 214 ? OE2 ? B GLU 213 OE2 
84 1 Y 1 H SER 135 ? OG  ? C SER 135 OG  
85 1 Y 1 H SER 136 ? OG  ? C SER 136 OG  
86 1 Y 1 H LYS 137 ? CG  ? C LYS 137 CG  
87 1 Y 1 H LYS 137 ? CD  ? C LYS 137 CD  
88 1 Y 1 H LYS 137 ? CE  ? C LYS 137 CE  
89 1 Y 1 H LYS 137 ? NZ  ? C LYS 137 NZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement        ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? '(1.20.1_4487: ???)' 1 
? 'data reduction'  ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                    2 
? 'data scaling'    ? ? ? ? ? ? ? ? ? ? ? HKL-3000 ? ? ? .                    3 
? phasing           ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .                    4 
? 'model building'  ? ? ? ? ? ? ? ? ? ? ? Coot     ? ? ? .                    5 
? 'data collection' ? ? ? ? ? ? ? ? ? ? ? SERGUI   ? ? ? .                    6 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8ULJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     164.715 
_cell.length_a_esd                 ? 
_cell.length_b                     164.715 
_cell.length_b_esd                 ? 
_cell.length_c                     146.157 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        6 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8ULJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                150 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 3 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8ULJ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             5.52 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          77.71 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'23.64%w/v PEG 1500, 0.1 M MMT buffer (DL-malic acid:MES:Tris base at a molar ratio of 1:2:2) with pH 4.36' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2018-10-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 22-ID' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   22-ID 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          68.20 
_reflns.entry_id                                       8ULJ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              3.0 
_reflns.d_resolution_low                               43.39 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     45920 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.4 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.98 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    3.0 
_reflns_shell.d_res_low                                     3.108 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             4550 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.952 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8ULJ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            3.00 
_refine.ls_d_res_low                             43.39 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     45465 
_refine.ls_number_reflns_R_free                  1982 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.45 
_refine.ls_percent_reflns_R_free                 4.36 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2382 
_refine.ls_R_factor_R_free                       0.2635 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2370 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.36 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ML 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.10 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.90 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.61 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.39 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       3.00 
_refine_hist.d_res_low                        43.39 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               6894 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6894 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 5.240 ? 969  ? f_dihedral_angle_d ? ? 
'X-RAY DIFFRACTION' ? 0.043 ? 1130 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.005 ? 1218 ? f_plane_restr      ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 3.00 3.08  . . 139 3063 99.00  . . . . 0.3129 . . . . . . . . . . . 0.3840 
'X-RAY DIFFRACTION' 3.08 3.16  . . 140 3082 99.00  . . . . 0.2901 . . . . . . . . . . . 0.3388 
'X-RAY DIFFRACTION' 3.16 3.25  . . 137 3078 98.00  . . . . 0.2783 . . . . . . . . . . . 0.3163 
'X-RAY DIFFRACTION' 3.25 3.36  . . 141 3062 98.00  . . . . 0.2874 . . . . . . . . . . . 0.2975 
'X-RAY DIFFRACTION' 3.36 3.48  . . 142 3048 98.00  . . . . 0.2642 . . . . . . . . . . . 0.2805 
'X-RAY DIFFRACTION' 3.48 3.62  . . 132 3047 97.00  . . . . 0.2587 . . . . . . . . . . . 0.3058 
'X-RAY DIFFRACTION' 3.62 3.78  . . 131 2903 93.00  . . . . 0.2589 . . . . . . . . . . . 0.2815 
'X-RAY DIFFRACTION' 3.78 3.98  . . 144 3087 99.00  . . . . 0.2570 . . . . . . . . . . . 0.2947 
'X-RAY DIFFRACTION' 3.98 4.23  . . 142 3167 100.00 . . . . 0.2248 . . . . . . . . . . . 0.2339 
'X-RAY DIFFRACTION' 4.23 4.56  . . 142 3151 100.00 . . . . 0.2018 . . . . . . . . . . . 0.2097 
'X-RAY DIFFRACTION' 4.56 5.01  . . 146 3167 100.00 . . . . 0.2060 . . . . . . . . . . . 0.1943 
'X-RAY DIFFRACTION' 5.01 5.74  . . 148 3148 100.00 . . . . 0.2285 . . . . . . . . . . . 0.2878 
'X-RAY DIFFRACTION' 5.74 7.22  . . 147 3169 99.00  . . . . 0.2537 . . . . . . . . . . . 0.2853 
'X-RAY DIFFRACTION' 7.23 43.39 . . 151 3311 99.00  . . . . 0.2066 . . . . . . . . . . . 0.2440 
# 
_struct.entry_id                     8ULJ 
_struct.title                        'Prefusion RSV F bound by neutralizing antibody 2E08' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8ULJ 
_struct_keywords.text            'RSV, antibody, neutralizing, prefusion, antiviral, VIRAL PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP FUS_HRSVA       P03420     ? 1 QNITEEFYQSTCSAVSKGYLSALRTGWYTSVITIELSNIKENKCNGTDAKVKLIKQELDKYKNAVTELQLLMQSTPPTN 26  
2 PDB 8ULJ            8ULJ       ? 2 ? 1   
3 PDB 8ULJ            8ULJ       ? 3 ? 1   
4 UNP A0A088S9A7_HRSV A0A088S9A7 ? 4 
;FLGFLLGVGSAIASGVAVSKVLHLEGEVNKIKSALLSTNKAVVSLSNGVSVLTSKVLDLKNYIDKQLLPIVNKQSCSISN
IETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMSNNVQIVRQQSYSIMSIIKEEV
LAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQAETCKVQSNRVFCDTMNSLTLP
SEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVDTVSVGNTL
YYVNKQEGKSLYVKGEPIINFYDPLVFPSDEFDASISQVNEKINQSLAFIRKSDELL
;
137 
5 UNP WAC_BPT4        P10104     ? 4 GYIPEAPRDGQAYVRKDGEWVFLSTFL 458 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8ULJ A 1   ? 79  ? P03420     26  ? 104 ? 26  104 
2 2 8ULJ L 1   ? 214 ? 8ULJ       2   ? 215 ? 2   215 
3 3 8ULJ H 1   ? 242 ? 8ULJ       1   ? 242 ? 1   242 
4 4 8ULJ B 1   ? 377 ? A0A088S9A7 137 ? 513 ? 137 513 
5 5 8ULJ B 382 ? 408 ? P10104     458 ? 484 ? 518 544 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8ULJ ALA A 77  ? UNP P03420     PRO 102 conflict         102 1  
4 8ULJ CYS B 19  ? UNP A0A088S9A7 SER 155 conflict         155 2  
4 8ULJ PHE B 54  ? UNP A0A088S9A7 SER 190 conflict         190 3  
4 8ULJ LEU B 71  ? UNP A0A088S9A7 VAL 207 conflict         207 4  
4 8ULJ CYS B 154 ? UNP A0A088S9A7 SER 290 conflict         290 5  
4 8ULJ SER B 378 ? UNP A0A088S9A7 ?   ?   linker           514 6  
4 8ULJ ALA B 379 ? UNP A0A088S9A7 ?   ?   linker           515 7  
4 8ULJ ILE B 380 ? UNP A0A088S9A7 ?   ?   linker           516 8  
4 8ULJ GLY B 381 ? UNP A0A088S9A7 ?   ?   linker           517 9  
5 8ULJ LEU B 403 ? UNP P10104     PHE 479 conflict         539 10 
5 8ULJ GLY B 409 ? UNP P10104     ?   ?   'expression tag' 545 11 
5 8ULJ GLY B 410 ? UNP P10104     ?   ?   'expression tag' 546 12 
5 8ULJ LEU B 411 ? UNP P10104     ?   ?   'expression tag' 547 13 
5 8ULJ VAL B 412 ? UNP P10104     ?   ?   'expression tag' 548 14 
5 8ULJ PRO B 413 ? UNP P10104     ?   ?   'expression tag' 549 15 
5 8ULJ ARG B 414 ? UNP P10104     ?   ?   'expression tag' 550 16 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dodecameric 
_pdbx_struct_assembly.oligomeric_count     12 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1,2,3 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z       1.0000000000  0.0000000000  0.0000000000 0.0000000000    0.0000000000  
1.0000000000  0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000 
2 'crystal symmetry operation' 2_565 -y,x-y+1,z  -0.5000000000 -0.8660254038 0.0000000000 -82.3575000000  0.8660254038  
-0.5000000000 0.0000000000 142.6473743844 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
3 'crystal symmetry operation' 3_455 -x+y-1,-x,z -0.5000000000 0.8660254038  0.0000000000 -164.7150000000 -0.8660254038 
-0.5000000000 0.0000000000 0.0000000000   0.0000000000 0.0000000000 1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASP A 48  ? GLN A 73  ? ASP A 73  GLN A 98  1 ? 26 
HELX_P HELX_P2  AA2 VAL B 28  ? ASN B 31  ? VAL L 29  ASN L 32  5 ? 4  
HELX_P HELX_P3  AA3 GLU B 79  ? PHE B 83  ? GLU L 80  PHE L 84  5 ? 5  
HELX_P HELX_P4  AA4 SER B 121 ? SER B 127 ? SER L 122 SER L 128 1 ? 7  
HELX_P HELX_P5  AA5 SER B 182 ? GLU B 187 ? SER L 183 GLU L 188 1 ? 6  
HELX_P HELX_P6  AA6 THR C 28  ? TYR C 32  ? THR H 28  TYR H 32  5 ? 5  
HELX_P HELX_P7  AA7 PRO C 53  ? GLY C 56  ? PRO H 53  GLY H 56  5 ? 4  
HELX_P HELX_P8  AA8 GLN C 62  ? GLN C 65  ? GLN H 62  GLN H 65  5 ? 4  
HELX_P HELX_P9  AA9 THR C 87  ? ALA C 91  ? THR H 87  ALA H 91  5 ? 5  
HELX_P HELX_P10 AB1 SER C 195 ? THR C 199 ? SER H 195 THR H 199 5 ? 5  
HELX_P HELX_P11 AB2 PHE D 1   ? LEU D 6   ? PHE B 137 LEU B 142 5 ? 6  
HELX_P HELX_P12 AB3 ILE D 12  ? HIS D 23  ? ILE B 148 HIS B 159 1 ? 12 
HELX_P HELX_P13 AB4 GLY D 26  ? LEU D 35  ? GLY B 162 LEU B 171 1 ? 10 
HELX_P HELX_P14 AB5 LEU D 59  ? LYS D 65  ? LEU B 195 LYS B 201 1 ? 7  
HELX_P HELX_P15 AB6 ASN D 80  ? ASN D 104 ? ASN B 216 ASN B 240 1 ? 25 
HELX_P HELX_P16 AB7 THR D 117 ? MET D 128 ? THR B 253 MET B 264 1 ? 12 
HELX_P HELX_P17 AB8 THR D 131 ? ASN D 141 ? THR B 267 ASN B 277 1 ? 11 
HELX_P HELX_P18 AB9 ASN D 141 ? GLN D 148 ? ASN B 277 GLN B 284 1 ? 8  
HELX_P HELX_P19 AC1 GLN D 218 ? CYS D 222 ? GLN B 354 CYS B 358 5 ? 5  
HELX_P HELX_P20 AC2 MET D 234 ? SER D 236 ? MET B 370 SER B 372 5 ? 3  
HELX_P HELX_P21 AC3 PRO D 240 ? VAL D 243 ? PRO B 376 VAL B 379 5 ? 4  
HELX_P HELX_P22 AC4 ASN D 244 ? ASP D 249 ? ASN B 380 ASP B 385 1 ? 6  
HELX_P HELX_P23 AC5 PRO D 337 ? TYR D 342 ? PRO B 473 TYR B 478 5 ? 6  
HELX_P HELX_P24 AC6 ASP D 343 ? PHE D 347 ? ASP B 479 PHE B 483 5 ? 5  
HELX_P HELX_P25 AC7 ILE D 356 ? GLY D 381 ? ILE B 492 GLY B 517 1 ? 26 
HELX_P HELX_P26 AC8 SER D 405 ? LEU D 408 ? SER B 541 LEU B 544 5 ? 4  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 12  SG ? ? ? 1_555 D CYS 303 SG ? ? A CYS 37  B CYS 439 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2  disulf ? ? A CYS 44  SG ? ? ? 1_555 D CYS 76  SG ? ? A CYS 69  B CYS 212 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf3  disulf ? ? B CYS 22  SG ? ? ? 1_555 B CYS 88  SG ? ? L CYS 23  L CYS 89  1_555 ? ? ? ? ? ? ? 2.043 ? ? 
disulf4  disulf ? ? C CYS 22  SG ? ? ? 1_555 C CYS 96  SG ? ? H CYS 22  H CYS 96  1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf5  disulf ? ? C CYS 148 SG ? ? ? 1_555 C CYS 204 SG ? ? H CYS 148 H CYS 204 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf6  disulf ? ? D CYS 19  SG ? ? ? 1_555 D CYS 154 SG ? ? B CYS 155 B CYS 290 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf7  disulf ? ? D CYS 177 SG ? ? ? 1_555 D CYS 207 SG ? ? B CYS 313 B CYS 343 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
disulf8  disulf ? ? D CYS 186 SG ? ? ? 1_555 D CYS 197 SG ? ? B CYS 322 B CYS 333 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf9  disulf ? ? D CYS 222 SG ? ? ? 1_555 D CYS 231 SG ? ? B CYS 358 B CYS 367 1_555 ? ? ? ? ? ? ? 2.040 ? ? 
disulf10 disulf ? ? D CYS 246 SG ? ? ? 1_555 D CYS 257 SG ? ? B CYS 382 B CYS 393 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf11 disulf ? ? D CYS 280 SG ? ? ? 1_555 D CYS 286 SG ? ? B CYS 416 B CYS 422 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 12  ? CYS D 303 ? CYS A 37  ? 1_555 CYS B 439 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 44  ? CYS D 76  ? CYS A 69  ? 1_555 CYS B 212 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS B 22  ? CYS B 88  ? CYS L 23  ? 1_555 CYS L 89  ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS C 22  ? CYS C 96  ? CYS H 22  ? 1_555 CYS H 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS C 148 ? CYS C 204 ? CYS H 148 ? 1_555 CYS H 204 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS D 19  ? CYS D 154 ? CYS B 155 ? 1_555 CYS B 290 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS D 177 ? CYS D 207 ? CYS B 313 ? 1_555 CYS B 343 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS D 186 ? CYS D 197 ? CYS B 322 ? 1_555 CYS B 333 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS D 222 ? CYS D 231 ? CYS B 358 ? 1_555 CYS B 367 ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS D 246 ? CYS D 257 ? CYS B 382 ? 1_555 CYS B 393 ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS D 280 ? CYS D 286 ? CYS B 416 ? 1_555 CYS B 422 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 SER 6   B . ? SER 7   L PRO 7   B ? PRO 8   L 1 -8.08 
2 SER 94  B . ? SER 95  L PRO 95  B ? PRO 96  L 1 -1.25 
3 THR 109 D . ? THR 245 B PRO 110 D ? PRO 246 B 1 1.45  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 6 ? 
AA4 ? 4 ? 
AA5 ? 6 ? 
AA6 ? 4 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
AB5 ? 2 ? 
AB6 ? 4 ? 
AB7 ? 3 ? 
AB8 ? 4 ? 
AB9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? anti-parallel 
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA3 2 3 ? parallel      
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA3 5 6 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA5 5 6 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LYS D 223 ? GLN D 225 ? LYS B 359 GLN B 361 
AA1 2 ARG D 228 ? ASP D 232 ? ARG B 364 ASP B 368 
AA1 3 SER A 13  ? ARG A 24  ? SER A 38  ARG A 49  
AA1 4 VAL D 172 ? THR D 182 ? VAL B 308 THR B 318 
AA1 5 GLY D 204 ? ASN D 209 ? GLY B 340 ASN B 345 
AA1 6 SER D 212 ? PHE D 216 ? SER B 348 PHE B 352 
AA1 7 LEU D 237 ? LEU D 239 ? LEU B 373 LEU B 375 
AA2 1 LYS D 223 ? GLN D 225 ? LYS B 359 GLN B 361 
AA2 2 ARG D 228 ? ASP D 232 ? ARG B 364 ASP B 368 
AA2 3 SER A 13  ? ARG A 24  ? SER A 38  ARG A 49  
AA2 4 THR A 4   ? TYR A 8   ? THR A 29  TYR A 33  
AA2 5 LYS D 329 ? VAL D 333 ? LYS B 465 VAL B 469 
AA3 1 LYS D 40  ? SER D 44  ? LYS B 176 SER B 180 
AA3 2 SER D 50  ? ASP D 58  ? SER B 186 ASP B 194 
AA3 3 GLY A 26  ? GLU A 35  ? GLY A 51  GLU A 60  
AA3 4 VAL D 160 ? LEU D 169 ? VAL B 296 LEU B 305 
AA3 5 TYR D 150 ? LYS D 157 ? TYR B 286 LYS B 293 
AA3 6 VAL D 107 ? THR D 108 ? VAL B 243 THR B 244 
AA4 1 THR B 4   ? SER B 6   ? THR L 5   SER L 7   
AA4 2 ALA B 18  ? ARG B 23  ? ALA L 19  ARG L 24  
AA4 3 ASP B 70  ? ILE B 75  ? ASP L 71  ILE L 76  
AA4 4 PHE B 62  ? SER B 67  ? PHE L 63  SER L 68  
AA5 1 THR B 9   ? LEU B 12  ? THR L 10  LEU L 13  
AA5 2 THR B 102 ? ILE B 106 ? THR L 103 ILE L 107 
AA5 3 VAL B 85  ? GLN B 90  ? VAL L 86  GLN L 91  
AA5 4 LEU B 33  ? GLN B 38  ? LEU L 34  GLN L 39  
AA5 5 ARG B 45  ? TYR B 49  ? ARG L 46  TYR L 50  
AA5 6 ASN B 53  ? ARG B 54  ? ASN L 54  ARG L 55  
AA6 1 THR B 9   ? LEU B 12  ? THR L 10  LEU L 13  
AA6 2 THR B 102 ? ILE B 106 ? THR L 103 ILE L 107 
AA6 3 VAL B 85  ? GLN B 90  ? VAL L 86  GLN L 91  
AA6 4 THR B 97  ? PHE B 98  ? THR L 98  PHE L 99  
AA7 1 ALA B 130 ? LEU B 135 ? ALA L 131 LEU L 136 
AA7 2 SER B 176 ? LEU B 181 ? SER L 177 LEU L 182 
AA7 3 SER B 159 ? SER B 162 ? SER L 160 SER L 163 
AA8 1 GLN B 147 ? VAL B 150 ? GLN L 148 VAL L 151 
AA8 2 TYR B 192 ? GLU B 195 ? TYR L 193 GLU L 196 
AA9 1 GLN C 3   ? GLU C 6   ? GLN H 3   GLU H 6   
AA9 2 VAL C 18  ? SER C 25  ? VAL H 18  SER H 25  
AA9 3 THR C 78  ? LEU C 83  ? THR H 78  LEU H 83  
AA9 4 LEU C 68  ? ASP C 73  ? LEU H 68  ASP H 73  
AB1 1 GLU C 10  ? LYS C 12  ? GLU H 10  LYS H 12  
AB1 2 THR C 115 ? VAL C 119 ? THR H 115 VAL H 119 
AB1 3 ALA C 92  ? THR C 98  ? ALA H 92  THR H 98  
AB1 4 ILE C 34  ? GLN C 39  ? ILE H 34  GLN H 39  
AB1 5 LEU C 45  ? ILE C 52  ? LEU H 45  ILE H 52  
AB1 6 THR C 57  ? GLU C 60  ? THR H 57  GLU H 60  
AB2 1 GLU C 10  ? LYS C 12  ? GLU H 10  LYS H 12  
AB2 2 THR C 115 ? VAL C 119 ? THR H 115 VAL H 119 
AB2 3 ALA C 92  ? THR C 98  ? ALA H 92  THR H 98  
AB2 4 VAL C 110 ? TRP C 111 ? VAL H 110 TRP H 111 
AB3 1 SER C 128 ? PRO C 131 ? SER H 128 PRO H 131 
AB3 2 CYS C 148 ? LYS C 151 ? CYS H 148 LYS H 151 
AB4 1 THR C 143 ? LEU C 146 ? THR H 143 LEU H 146 
AB4 2 VAL C 190 ? PRO C 193 ? VAL H 190 PRO H 193 
AB5 1 TYR C 202 ? VAL C 206 ? TYR H 202 VAL H 206 
AB5 2 VAL C 215 ? VAL C 219 ? VAL H 215 VAL H 219 
AB6 1 LEU D 185 ? CYS D 186 ? LEU B 321 CYS B 322 
AB6 2 CYS D 197 ? ARG D 200 ? CYS B 333 ARG B 336 
AB6 3 LYS D 258 ? SER D 262 ? LYS B 394 SER B 398 
AB6 4 ALA D 354 ? SER D 355 ? ALA B 490 SER B 491 
AB7 1 SER D 268 ? ILE D 271 ? SER B 404 ILE B 407 
AB7 2 GLY D 275 ? CYS D 280 ? GLY B 411 CYS B 416 
AB7 3 GLY D 302 ? SER D 307 ? GLY B 438 SER B 443 
AB8 1 GLY D 294 ? THR D 298 ? GLY B 430 THR B 434 
AB8 2 CYS D 286 ? ASN D 290 ? CYS B 422 ASN B 426 
AB8 3 THR D 313 ? VAL D 316 ? THR B 449 VAL B 452 
AB8 4 THR D 319 ? TYR D 322 ? THR B 455 TYR B 458 
AB9 1 TYR D 394 ? ARG D 396 ? TYR B 530 ARG B 532 
AB9 2 TRP D 401 ? LEU D 403 ? TRP B 537 LEU B 539 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N LYS D 223 ? N LYS B 359 O PHE D 230 ? O PHE B 366 
AA1 2 3 O CYS D 231 ? O CYS B 367 N ARG A 24  ? N ARG A 49  
AA1 3 4 N ALA A 14  ? N ALA A 39  O HIS D 181 ? O HIS B 317 
AA1 4 5 N LEU D 180 ? N LEU B 316 O GLY D 204 ? O GLY B 340 
AA1 5 6 N TRP D 205 ? N TRP B 341 O PHE D 216 ? O PHE B 352 
AA1 6 7 N PHE D 215 ? N PHE B 351 O LEU D 237 ? O LEU B 373 
AA2 1 2 N LYS D 223 ? N LYS B 359 O PHE D 230 ? O PHE B 366 
AA2 2 3 O CYS D 231 ? O CYS B 367 N ARG A 24  ? N ARG A 49  
AA2 3 4 O SER A 13  ? O SER A 38  N TYR A 8   ? N TYR A 33  
AA2 4 5 N PHE A 7   ? N PHE A 32  O VAL D 333 ? O VAL B 469 
AA3 1 2 N VAL D 43  ? N VAL B 179 O VAL D 51  ? O VAL B 187 
AA3 2 3 O PHE D 54  ? O PHE B 190 N THR A 33  ? N THR A 58  
AA3 3 4 N ILE A 32  ? N ILE A 57  O TYR D 163 ? O TYR B 299 
AA3 4 5 O GLN D 166 ? O GLN B 302 N TYR D 150 ? N TYR B 286 
AA3 5 6 O SER D 151 ? O SER B 287 N THR D 108 ? N THR B 244 
AA4 1 2 N THR B 4   ? N THR L 5   O ARG B 23  ? O ARG L 24  
AA4 2 3 N LEU B 20  ? N LEU L 21  O LEU B 73  ? O LEU L 74  
AA4 3 4 O THR B 72  ? O THR L 73  N SER B 65  ? N SER L 66  
AA5 1 2 N LEU B 10  ? N LEU L 11  O LYS B 103 ? O LYS L 104 
AA5 2 3 O THR B 102 ? O THR L 103 N TYR B 86  ? N TYR L 87  
AA5 3 4 O GLN B 89  ? O GLN L 90  N ALA B 34  ? N ALA L 35  
AA5 4 5 N GLN B 37  ? N GLN L 38  O ARG B 45  ? O ARG L 46  
AA5 5 6 N TYR B 49  ? N TYR L 50  O ASN B 53  ? O ASN L 54  
AA6 1 2 N LEU B 10  ? N LEU L 11  O LYS B 103 ? O LYS L 104 
AA6 2 3 O THR B 102 ? O THR L 103 N TYR B 86  ? N TYR L 87  
AA6 3 4 N GLN B 90  ? N GLN L 91  O THR B 97  ? O THR L 98  
AA7 1 2 N ALA B 130 ? N ALA L 131 O LEU B 181 ? O LEU L 182 
AA7 2 3 O SER B 176 ? O SER L 177 N SER B 162 ? N SER L 163 
AA8 1 2 N LYS B 149 ? N LYS L 150 O ALA B 193 ? O ALA L 194 
AA9 1 2 N VAL C 5   ? N VAL H 5   O LYS C 23  ? O LYS H 23  
AA9 2 3 N VAL C 18  ? N VAL H 18  O LEU C 83  ? O LEU H 83  
AA9 3 4 O THR C 78  ? O THR H 78  N ASP C 73  ? N ASP H 73  
AB1 1 2 N GLU C 10  ? N GLU H 10  O ARG C 116 ? O ARG H 116 
AB1 2 3 O THR C 115 ? O THR H 115 N TYR C 94  ? N TYR H 94  
AB1 3 4 O PHE C 95  ? O PHE H 95  N VAL C 37  ? N VAL H 37  
AB1 4 5 N ARG C 38  ? N ARG H 38  O GLU C 46  ? O GLU H 46  
AB1 5 6 N GLY C 50  ? N GLY H 50  O TYR C 59  ? O TYR H 59  
AB2 1 2 N GLU C 10  ? N GLU H 10  O ARG C 116 ? O ARG H 116 
AB2 2 3 O THR C 115 ? O THR H 115 N TYR C 94  ? N TYR H 94  
AB2 3 4 N THR C 98  ? N THR H 98  O VAL C 110 ? O VAL H 110 
AB3 1 2 N PHE C 130 ? N PHE H 130 O LEU C 149 ? O LEU H 149 
AB4 1 2 N LEU C 146 ? N LEU H 146 O VAL C 190 ? O VAL H 190 
AB5 1 2 N CYS C 204 ? N CYS H 204 O LYS C 217 ? O LYS H 217 
AB6 1 2 N LEU D 185 ? N LEU B 321 O LEU D 198 ? O LEU B 334 
AB6 2 3 N CYS D 197 ? N CYS B 333 O SER D 262 ? O SER B 398 
AB6 3 4 N ILE D 259 ? N ILE B 395 O ALA D 354 ? O ALA B 490 
AB7 1 2 N VAL D 270 ? N VAL B 406 O ILE D 277 ? O ILE B 413 
AB7 2 3 N CYS D 280 ? N CYS B 416 O GLY D 302 ? O GLY B 438 
AB8 1 2 O GLY D 294 ? O GLY B 430 N ASN D 290 ? N ASN B 426 
AB8 2 3 N SER D 289 ? N SER B 425 O THR D 313 ? O THR B 449 
AB8 3 4 N VAL D 314 ? N VAL B 450 O TYR D 321 ? O TYR B 457 
AB9 1 2 N VAL D 395 ? N VAL B 531 O VAL D 402 ? O VAL B 538 
# 
_pdbx_entry_details.entry_id                   8ULJ 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 CYS A 69  ? ? -161.79 115.83  
2  1 GLN A 98  ? ? -68.37  0.71    
3  1 VAL L 4   ? ? 34.77   96.46   
4  1 ALA L 52  ? ? 73.42   -10.16  
5  1 SER L 53  ? ? -141.04 -16.23  
6  1 ALA L 112 ? ? 64.43   165.47  
7  1 ALA L 113 ? ? -163.19 65.53   
8  1 ASP L 123 ? ? -86.99  -71.34  
9  1 ASN L 138 ? ? -150.69 -159.55 
10 1 ASN L 139 ? ? -23.31  101.35  
11 1 TYR L 141 ? ? -101.07 -61.08  
12 1 ARG L 143 ? ? -69.46  77.15   
13 1 LYS L 146 ? ? 68.59   126.53  
14 1 VAL L 147 ? ? -123.06 -63.08  
15 1 ASP L 171 ? ? -141.89 -8.71   
16 1 THR L 173 ? ? -149.37 -137.97 
17 1 TYR L 174 ? ? 92.89   174.02  
18 1 PHE L 210 ? ? -140.61 54.22   
19 1 ILE H 105 ? ? 63.92   -71.61  
20 1 SER H 135 ? ? -94.80  -68.27  
21 1 SER H 136 ? ? -127.79 -53.03  
22 1 ASP H 152 ? ? 62.14   65.37   
23 1 PHE H 154 ? ? -172.94 -60.43  
24 1 GLU H 156 ? ? 70.17   151.56  
25 1 ASN H 163 ? ? 59.16   17.14   
26 1 SER H 164 ? ? -77.91  -169.47 
27 1 THR H 168 ? ? 38.88   -133.08 
28 1 ALA H 176 ? ? 60.45   65.99   
29 1 SER H 211 ? ? 166.69  -44.81  
30 1 THR H 213 ? ? 177.84  166.23  
31 1 LEU B 171 ? ? -93.38  52.52   
32 1 LYS B 201 ? ? -72.92  -93.09  
33 1 LEU B 203 ? ? 64.61   159.00  
34 1 LEU B 207 ? ? 49.94   71.40   
35 1 GLN B 210 ? ? 66.33   -6.68   
36 1 SER B 211 ? ? -100.65 -60.36  
37 1 CYS B 212 ? ? 59.70   2.60    
38 1 CYS B 290 ? ? -94.61  -62.63  
39 1 SER B 362 ? ? 57.59   -104.59 
40 1 ASP B 534 ? ? -120.05 -62.26  
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 ARG L 108 ? ? 0.129 'SIDE CHAIN' 
2 1 ARG L 109 ? ? 0.138 'SIDE CHAIN' 
3 1 ARG L 212 ? ? 0.289 'SIDE CHAIN' 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z      
2 -y,x-y,z   
3 -x+y,-x,z  
4 x-y,-y,-z  
5 -x,-x+y,-z 
6 y,x,-z     
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLN 26  ? A GLN 1   
2  1 Y 1 L VAL 116 ? B VAL 115 
3  1 Y 1 L PHE 117 ? B PHE 116 
4  1 Y 1 L ILE 118 ? B ILE 117 
5  1 Y 1 L PHE 119 ? B PHE 118 
6  1 Y 1 L CYS 215 ? B CYS 214 
7  1 Y 1 H SER 138 ? C SER 138 
8  1 Y 1 H THR 139 ? C THR 139 
9  1 Y 1 H SER 140 ? C SER 140 
10 1 Y 1 H GLY 141 ? C GLY 141 
11 1 Y 1 H LYS 222 ? C LYS 222 
12 1 Y 1 H SER 223 ? C SER 223 
13 1 Y 1 H CYS 224 ? C CYS 224 
14 1 Y 1 H ASP 225 ? C ASP 225 
15 1 Y 1 H LYS 226 ? C LYS 226 
16 1 Y 1 H GLY 227 ? C GLY 227 
17 1 Y 1 H SER 228 ? C SER 228 
18 1 Y 1 H GLU 229 ? C GLU 229 
19 1 Y 1 H ASN 230 ? C ASN 230 
20 1 Y 1 H LEU 231 ? C LEU 231 
21 1 Y 1 H TYR 232 ? C TYR 232 
22 1 Y 1 H PHE 233 ? C PHE 233 
23 1 Y 1 H GLN 234 ? C GLN 234 
24 1 Y 1 H GLY 235 ? C GLY 235 
25 1 Y 1 H SER 236 ? C SER 236 
26 1 Y 1 H HIS 237 ? C HIS 237 
27 1 Y 1 H HIS 238 ? C HIS 238 
28 1 Y 1 H HIS 239 ? C HIS 239 
29 1 Y 1 H HIS 240 ? C HIS 240 
30 1 Y 1 H HIS 241 ? C HIS 241 
31 1 Y 1 H HIS 242 ? C HIS 242 
32 1 Y 1 B GLY 545 ? D GLY 409 
33 1 Y 1 B GLY 546 ? D GLY 410 
34 1 Y 1 B LEU 547 ? D LEU 411 
35 1 Y 1 B VAL 548 ? D VAL 412 
36 1 Y 1 B PRO 549 ? D PRO 413 
37 1 Y 1 B ARG 550 ? D ARG 414 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                ? 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_initial_refinement_model.id 
_pdbx_initial_refinement_model.entity_id_list 
_pdbx_initial_refinement_model.type 
_pdbx_initial_refinement_model.source_name 
_pdbx_initial_refinement_model.accession_code 
_pdbx_initial_refinement_model.details 
1 ? 'experimental model' PDB   4MMU ?                                                                 
2 ? 'in silico model'    Other ?    'homology model built with Molecular Operating Environment (MOE)' 
# 
_space_group.name_H-M_alt     'P 3 2 1' 
_space_group.name_Hall        
;P 3 2"
;
_space_group.IT_number        150 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8ULJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.006071 
_atom_sites.fract_transf_matrix[1][2]   0.003505 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007010 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.006842 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 6.96715 ?       ? ? 11.43723 ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527 ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ASN A 1 2   ? -109.820 27.681  0.699   1.00 70.14  ? 27  ASN A N   1 
ATOM 2    C CA  . ASN A 1 2   ? -108.474 28.167  0.417   1.00 73.83  ? 27  ASN A CA  1 
ATOM 3    C C   . ASN A 1 2   ? -107.864 28.890  1.618   1.00 76.08  ? 27  ASN A C   1 
ATOM 4    O O   . ASN A 1 2   ? -107.469 28.258  2.597   1.00 71.51  ? 27  ASN A O   1 
ATOM 5    C CB  . ASN A 1 2   ? -108.483 29.094  -0.802  1.00 80.12  ? 27  ASN A CB  1 
ATOM 6    C CG  . ASN A 1 2   ? -107.752 28.501  -1.993  1.00 91.69  ? 27  ASN A CG  1 
ATOM 7    O OD1 . ASN A 1 2   ? -107.312 27.352  -1.956  1.00 102.65 ? 27  ASN A OD1 1 
ATOM 8    N ND2 . ASN A 1 2   ? -107.615 29.287  -3.055  1.00 86.51  ? 27  ASN A ND2 1 
ATOM 9    N N   . ILE A 1 3   ? -107.796 30.217  1.540   1.00 76.93  ? 28  ILE A N   1 
ATOM 10   C CA  . ILE A 1 3   ? -107.096 31.022  2.535   1.00 68.71  ? 28  ILE A CA  1 
ATOM 11   C C   . ILE A 1 3   ? -108.071 31.448  3.623   1.00 65.40  ? 28  ILE A C   1 
ATOM 12   O O   . ILE A 1 3   ? -109.145 31.988  3.335   1.00 77.92  ? 28  ILE A O   1 
ATOM 13   C CB  . ILE A 1 3   ? -106.436 32.249  1.885   1.00 69.89  ? 28  ILE A CB  1 
ATOM 14   C CG1 . ILE A 1 3   ? -105.533 31.820  0.728   1.00 64.71  ? 28  ILE A CG1 1 
ATOM 15   C CG2 . ILE A 1 3   ? -105.650 33.039  2.923   1.00 57.95  ? 28  ILE A CG2 1 
ATOM 16   C CD1 . ILE A 1 3   ? -104.345 30.991  1.158   1.00 65.06  ? 28  ILE A CD1 1 
ATOM 17   N N   . THR A 1 4   ? -107.691 31.213  4.877   1.00 66.55  ? 29  THR A N   1 
ATOM 18   C CA  . THR A 1 4   ? -108.468 31.631  6.034   1.00 62.10  ? 29  THR A CA  1 
ATOM 19   C C   . THR A 1 4   ? -107.580 32.431  6.977   1.00 56.09  ? 29  THR A C   1 
ATOM 20   O O   . THR A 1 4   ? -106.360 32.246  7.014   1.00 59.15  ? 29  THR A O   1 
ATOM 21   C CB  . THR A 1 4   ? -109.065 30.435  6.782   1.00 57.56  ? 29  THR A CB  1 
ATOM 22   O OG1 . THR A 1 4   ? -108.011 29.691  7.406   1.00 67.12  ? 29  THR A OG1 1 
ATOM 23   C CG2 . THR A 1 4   ? -109.828 29.530  5.826   1.00 58.31  ? 29  THR A CG2 1 
ATOM 24   N N   . GLU A 1 5   ? -108.203 33.319  7.748   1.00 53.75  ? 30  GLU A N   1 
ATOM 25   C CA  . GLU A 1 5   ? -107.470 34.226  8.619   1.00 62.43  ? 30  GLU A CA  1 
ATOM 26   C C   . GLU A 1 5   ? -108.168 34.337  9.967   1.00 54.76  ? 30  GLU A C   1 
ATOM 27   O O   . GLU A 1 5   ? -109.399 34.405  10.032  1.00 62.45  ? 30  GLU A O   1 
ATOM 28   C CB  . GLU A 1 5   ? -107.342 35.609  7.971   1.00 58.91  ? 30  GLU A CB  1 
ATOM 29   C CG  . GLU A 1 5   ? -106.481 36.587  8.738   1.00 54.54  ? 30  GLU A CG  1 
ATOM 30   C CD  . GLU A 1 5   ? -106.126 37.802  7.908   1.00 59.99  ? 30  GLU A CD  1 
ATOM 31   O OE1 . GLU A 1 5   ? -105.184 37.707  7.094   1.00 54.13  ? 30  GLU A OE1 1 
ATOM 32   O OE2 . GLU A 1 5   ? -106.790 38.848  8.064   1.00 63.13  ? 30  GLU A OE2 1 
ATOM 33   N N   . GLU A 1 6   ? -107.377 34.353  11.040  1.00 52.54  ? 31  GLU A N   1 
ATOM 34   C CA  . GLU A 1 6   ? -107.889 34.488  12.399  1.00 56.51  ? 31  GLU A CA  1 
ATOM 35   C C   . GLU A 1 6   ? -107.159 35.618  13.109  1.00 57.12  ? 31  GLU A C   1 
ATOM 36   O O   . GLU A 1 6   ? -105.927 35.694  13.058  1.00 52.13  ? 31  GLU A O   1 
ATOM 37   C CB  . GLU A 1 6   ? -107.729 33.189  13.193  1.00 59.55  ? 31  GLU A CB  1 
ATOM 38   C CG  . GLU A 1 6   ? -108.531 32.024  12.655  1.00 82.69  ? 31  GLU A CG  1 
ATOM 39   C CD  . GLU A 1 6   ? -108.351 30.766  13.482  1.00 101.46 ? 31  GLU A CD  1 
ATOM 40   O OE1 . GLU A 1 6   ? -107.601 30.811  14.481  1.00 93.42  ? 31  GLU A OE1 1 
ATOM 41   O OE2 . GLU A 1 6   ? -108.965 29.735  13.135  1.00 120.53 ? 31  GLU A OE2 1 
ATOM 42   N N   . PHE A 1 7   ? -107.915 36.483  13.777  1.00 43.35  ? 32  PHE A N   1 
ATOM 43   C CA  . PHE A 1 7   ? -107.359 37.613  14.508  1.00 46.21  ? 32  PHE A CA  1 
ATOM 44   C C   . PHE A 1 7   ? -107.492 37.363  16.004  1.00 61.90  ? 32  PHE A C   1 
ATOM 45   O O   . PHE A 1 7   ? -108.587 37.072  16.497  1.00 56.84  ? 32  PHE A O   1 
ATOM 46   C CB  . PHE A 1 7   ? -108.064 38.915  14.124  1.00 39.83  ? 32  PHE A CB  1 
ATOM 47   C CG  . PHE A 1 7   ? -107.761 40.062  15.043  1.00 51.37  ? 32  PHE A CG  1 
ATOM 48   C CD1 . PHE A 1 7   ? -106.559 40.746  14.945  1.00 49.69  ? 32  PHE A CD1 1 
ATOM 49   C CD2 . PHE A 1 7   ? -108.679 40.464  16.001  1.00 56.42  ? 32  PHE A CD2 1 
ATOM 50   C CE1 . PHE A 1 7   ? -106.279 41.808  15.788  1.00 53.57  ? 32  PHE A CE1 1 
ATOM 51   C CE2 . PHE A 1 7   ? -108.404 41.525  16.844  1.00 42.53  ? 32  PHE A CE2 1 
ATOM 52   C CZ  . PHE A 1 7   ? -107.205 42.197  16.738  1.00 44.92  ? 32  PHE A CZ  1 
ATOM 53   N N   . TYR A 1 8   ? -106.380 37.480  16.722  1.00 60.27  ? 33  TYR A N   1 
ATOM 54   C CA  . TYR A 1 8   ? -106.352 37.284  18.167  1.00 52.92  ? 33  TYR A CA  1 
ATOM 55   C C   . TYR A 1 8   ? -106.326 38.651  18.839  1.00 56.83  ? 33  TYR A C   1 
ATOM 56   O O   . TYR A 1 8   ? -105.313 39.357  18.797  1.00 55.49  ? 33  TYR A O   1 
ATOM 57   C CB  . TYR A 1 8   ? -105.153 36.431  18.572  1.00 53.48  ? 33  TYR A CB  1 
ATOM 58   C CG  . TYR A 1 8   ? -105.019 35.181  17.737  1.00 57.60  ? 33  TYR A CG  1 
ATOM 59   C CD1 . TYR A 1 8   ? -105.827 34.077  17.976  1.00 59.06  ? 33  TYR A CD1 1 
ATOM 60   C CD2 . TYR A 1 8   ? -104.094 35.106  16.704  1.00 50.59  ? 33  TYR A CD2 1 
ATOM 61   C CE1 . TYR A 1 8   ? -105.717 32.932  17.213  1.00 72.00  ? 33  TYR A CE1 1 
ATOM 62   C CE2 . TYR A 1 8   ? -103.975 33.963  15.937  1.00 63.88  ? 33  TYR A CE2 1 
ATOM 63   C CZ  . TYR A 1 8   ? -104.790 32.880  16.194  1.00 68.53  ? 33  TYR A CZ  1 
ATOM 64   O OH  . TYR A 1 8   ? -104.678 31.739  15.433  1.00 74.39  ? 33  TYR A OH  1 
ATOM 65   N N   . GLN A 1 9   ? -107.447 39.017  19.462  1.00 63.61  ? 34  GLN A N   1 
ATOM 66   C CA  . GLN A 1 9   ? -107.562 40.327  20.090  1.00 52.51  ? 34  GLN A CA  1 
ATOM 67   C C   . GLN A 1 9   ? -106.645 40.458  21.297  1.00 52.57  ? 34  GLN A C   1 
ATOM 68   O O   . GLN A 1 9   ? -106.174 41.561  21.598  1.00 57.02  ? 34  GLN A O   1 
ATOM 69   C CB  . GLN A 1 9   ? -109.013 40.578  20.493  1.00 51.24  ? 34  GLN A CB  1 
ATOM 70   C CG  . GLN A 1 9   ? -109.292 41.973  21.015  1.00 60.88  ? 34  GLN A CG  1 
ATOM 71   C CD  . GLN A 1 9   ? -110.698 42.110  21.555  1.00 59.05  ? 34  GLN A CD  1 
ATOM 72   O OE1 . GLN A 1 9   ? -111.341 41.118  21.899  1.00 55.97  ? 34  GLN A OE1 1 
ATOM 73   N NE2 . GLN A 1 9   ? -111.189 43.341  21.625  1.00 70.59  ? 34  GLN A NE2 1 
ATOM 74   N N   . SER A 1 10  ? -106.383 39.352  21.999  1.00 47.92  ? 35  SER A N   1 
ATOM 75   C CA  . SER A 1 10  ? -105.563 39.420  23.203  1.00 49.61  ? 35  SER A CA  1 
ATOM 76   C C   . SER A 1 10  ? -104.144 39.881  22.890  1.00 55.53  ? 35  SER A C   1 
ATOM 77   O O   . SER A 1 10  ? -103.590 40.729  23.598  1.00 60.47  ? 35  SER A O   1 
ATOM 78   C CB  . SER A 1 10  ? -105.546 38.061  23.902  1.00 60.56  ? 35  SER A CB  1 
ATOM 79   O OG  . SER A 1 10  ? -104.972 37.065  23.076  1.00 61.36  ? 35  SER A OG  1 
ATOM 80   N N   . THR A 1 11  ? -103.542 39.349  21.828  1.00 61.18  ? 36  THR A N   1 
ATOM 81   C CA  . THR A 1 11  ? -102.158 39.654  21.491  1.00 55.15  ? 36  THR A CA  1 
ATOM 82   C C   . THR A 1 11  ? -102.015 40.623  20.323  1.00 50.67  ? 36  THR A C   1 
ATOM 83   O O   . THR A 1 11  ? -100.883 40.933  19.934  1.00 48.87  ? 36  THR A O   1 
ATOM 84   C CB  . THR A 1 11  ? -101.392 38.360  21.189  1.00 53.14  ? 36  THR A CB  1 
ATOM 85   O OG1 . THR A 1 11  ? -101.860 37.799  19.957  1.00 51.57  ? 36  THR A OG1 1 
ATOM 86   C CG2 . THR A 1 11  ? -101.590 37.349  22.311  1.00 61.94  ? 36  THR A CG2 1 
ATOM 87   N N   . CYS A 1 12  ? -103.125 41.122  19.770  1.00 54.38  ? 37  CYS A N   1 
ATOM 88   C CA  . CYS A 1 12  ? -103.109 42.068  18.649  1.00 49.86  ? 37  CYS A CA  1 
ATOM 89   C C   . CYS A 1 12  ? -102.330 41.501  17.460  1.00 55.21  ? 37  CYS A C   1 
ATOM 90   O O   . CYS A 1 12  ? -101.450 42.150  16.890  1.00 46.38  ? 37  CYS A O   1 
ATOM 91   C CB  . CYS A 1 12  ? -102.548 43.425  19.087  1.00 61.91  ? 37  CYS A CB  1 
ATOM 92   S SG  . CYS A 1 12  ? -102.654 44.760  17.857  1.00 64.17  ? 37  CYS A SG  1 
ATOM 93   N N   . SER A 1 13  ? -102.665 40.270  17.084  1.00 46.56  ? 38  SER A N   1 
ATOM 94   C CA  . SER A 1 13  ? -101.966 39.574  16.016  1.00 51.76  ? 38  SER A CA  1 
ATOM 95   C C   . SER A 1 13  ? -102.973 38.824  15.154  1.00 51.50  ? 38  SER A C   1 
ATOM 96   O O   . SER A 1 13  ? -104.120 38.605  15.551  1.00 48.83  ? 38  SER A O   1 
ATOM 97   C CB  . SER A 1 13  ? -100.910 38.614  16.579  1.00 49.80  ? 38  SER A CB  1 
ATOM 98   O OG  . SER A 1 13  ? -101.484 37.736  17.530  1.00 56.39  ? 38  SER A OG  1 
ATOM 99   N N   . ALA A 1 14  ? -102.532 38.441  13.954  1.00 50.09  ? 39  ALA A N   1 
ATOM 100  C CA  . ALA A 1 14  ? -103.368 37.703  13.018  1.00 46.52  ? 39  ALA A CA  1 
ATOM 101  C C   . ALA A 1 14  ? -102.541 36.636  12.315  1.00 46.75  ? 39  ALA A C   1 
ATOM 102  O O   . ALA A 1 14  ? -101.350 36.823  12.053  1.00 48.53  ? 39  ALA A O   1 
ATOM 103  C CB  . ALA A 1 14  ? -104.013 38.628  11.977  1.00 43.16  ? 39  ALA A CB  1 
ATOM 104  N N   . VAL A 1 15  ? -103.192 35.518  11.999  1.00 50.45  ? 40  VAL A N   1 
ATOM 105  C CA  . VAL A 1 15  ? -102.564 34.402  11.300  1.00 59.36  ? 40  VAL A CA  1 
ATOM 106  C C   . VAL A 1 15  ? -103.394 34.067  10.068  1.00 53.50  ? 40  VAL A C   1 
ATOM 107  O O   . VAL A 1 15  ? -104.606 33.848  10.173  1.00 63.30  ? 40  VAL A O   1 
ATOM 108  C CB  . VAL A 1 15  ? -102.422 33.163  12.207  1.00 56.10  ? 40  VAL A CB  1 
ATOM 109  C CG1 . VAL A 1 15  ? -101.870 31.989  11.413  1.00 69.41  ? 40  VAL A CG1 1 
ATOM 110  C CG2 . VAL A 1 15  ? -101.526 33.470  13.394  1.00 47.66  ? 40  VAL A CG2 1 
ATOM 111  N N   . SER A 1 16  ? -102.742 34.015  8.906   1.00 55.94  ? 41  SER A N   1 
ATOM 112  C CA  . SER A 1 16  ? -103.383 33.666  7.640   1.00 57.69  ? 41  SER A CA  1 
ATOM 113  C C   . SER A 1 16  ? -102.918 32.271  7.243   1.00 56.41  ? 41  SER A C   1 
ATOM 114  O O   . SER A 1 16  ? -101.745 32.076  6.910   1.00 62.47  ? 41  SER A O   1 
ATOM 115  C CB  . SER A 1 16  ? -103.038 34.677  6.548   1.00 49.15  ? 41  SER A CB  1 
ATOM 116  O OG  . SER A 1 16  ? -103.183 36.009  7.006   1.00 67.47  ? 41  SER A OG  1 
ATOM 117  N N   . LYS A 1 17  ? -103.828 31.305  7.273   1.00 62.51  ? 42  LYS A N   1 
ATOM 118  C CA  . LYS A 1 17  ? -103.497 29.927  6.946   1.00 54.84  ? 42  LYS A CA  1 
ATOM 119  C C   . LYS A 1 17  ? -104.034 29.567  5.564   1.00 56.57  ? 42  LYS A C   1 
ATOM 120  O O   . LYS A 1 17  ? -104.777 30.324  4.936   1.00 64.49  ? 42  LYS A O   1 
ATOM 121  C CB  . LYS A 1 17  ? -104.051 28.967  8.008   1.00 61.71  ? 42  LYS A CB  1 
ATOM 122  C CG  . LYS A 1 17  ? -103.627 29.288  9.442   1.00 71.83  ? 42  LYS A CG  1 
ATOM 123  C CD  . LYS A 1 17  ? -104.046 28.188  10.419  1.00 85.68  ? 42  LYS A CD  1 
ATOM 124  C CE  . LYS A 1 17  ? -102.946 27.146  10.638  1.00 103.84 ? 42  LYS A CE  1 
ATOM 125  N NZ  . LYS A 1 17  ? -101.967 27.522  11.713  1.00 71.86  ? 42  LYS A NZ  1 
ATOM 126  N N   . GLY A 1 18  ? -103.631 28.392  5.086   1.00 61.31  ? 43  GLY A N   1 
ATOM 127  C CA  . GLY A 1 18  ? -104.104 27.873  3.821   1.00 63.41  ? 43  GLY A CA  1 
ATOM 128  C C   . GLY A 1 18  ? -103.134 27.962  2.662   1.00 56.07  ? 43  GLY A C   1 
ATOM 129  O O   . GLY A 1 18  ? -103.538 27.701  1.523   1.00 62.43  ? 43  GLY A O   1 
ATOM 130  N N   . TYR A 1 19  ? -101.879 28.318  2.906   1.00 64.52  ? 44  TYR A N   1 
ATOM 131  C CA  . TYR A 1 19  ? -100.896 28.455  1.844   1.00 47.10  ? 44  TYR A CA  1 
ATOM 132  C C   . TYR A 1 19  ? -100.089 27.169  1.680   1.00 55.37  ? 44  TYR A C   1 
ATOM 133  O O   . TYR A 1 19  ? -99.996  26.340  2.588   1.00 62.58  ? 44  TYR A O   1 
ATOM 134  C CB  . TYR A 1 19  ? -99.967  29.636  2.126   1.00 54.96  ? 44  TYR A CB  1 
ATOM 135  C CG  . TYR A 1 19  ? -100.669 30.977  2.151   1.00 53.96  ? 44  TYR A CG  1 
ATOM 136  C CD1 . TYR A 1 19  ? -101.252 31.459  3.318   1.00 58.69  ? 44  TYR A CD1 1 
ATOM 137  C CD2 . TYR A 1 19  ? -100.746 31.763  1.008   1.00 45.82  ? 44  TYR A CD2 1 
ATOM 138  C CE1 . TYR A 1 19  ? -101.896 32.683  3.343   1.00 55.33  ? 44  TYR A CE1 1 
ATOM 139  C CE2 . TYR A 1 19  ? -101.384 32.987  1.023   1.00 51.32  ? 44  TYR A CE2 1 
ATOM 140  C CZ  . TYR A 1 19  ? -101.959 33.444  2.193   1.00 57.70  ? 44  TYR A CZ  1 
ATOM 141  O OH  . TYR A 1 19  ? -102.599 34.665  2.210   1.00 47.22  ? 44  TYR A OH  1 
ATOM 142  N N   . LEU A 1 20  ? -99.509  27.009  0.494   1.00 52.98  ? 45  LEU A N   1 
ATOM 143  C CA  . LEU A 1 20  ? -98.695  25.852  0.158   1.00 51.87  ? 45  LEU A CA  1 
ATOM 144  C C   . LEU A 1 20  ? -97.250  26.277  -0.069  1.00 54.64  ? 45  LEU A C   1 
ATOM 145  O O   . LEU A 1 20  ? -96.976  27.379  -0.554  1.00 57.18  ? 45  LEU A O   1 
ATOM 146  C CB  . LEU A 1 20  ? -99.236  25.140  -1.084  1.00 61.51  ? 45  LEU A CB  1 
ATOM 147  C CG  . LEU A 1 20  ? -100.549 24.392  -0.859  1.00 55.08  ? 45  LEU A CG  1 
ATOM 148  C CD1 . LEU A 1 20  ? -101.069 23.808  -2.161  1.00 60.99  ? 45  LEU A CD1 1 
ATOM 149  C CD2 . LEU A 1 20  ? -100.354 23.300  0.176   1.00 56.78  ? 45  LEU A CD2 1 
ATOM 150  N N   . SER A 1 21  ? -96.327  25.389  0.284   1.00 49.22  ? 46  SER A N   1 
ATOM 151  C CA  . SER A 1 21  ? -94.915  25.733  0.345   1.00 48.68  ? 46  SER A CA  1 
ATOM 152  C C   . SER A 1 21  ? -94.194  25.432  -0.961  1.00 55.52  ? 46  SER A C   1 
ATOM 153  O O   . SER A 1 21  ? -94.557  24.521  -1.711  1.00 53.87  ? 46  SER A O   1 
ATOM 154  C CB  . SER A 1 21  ? -94.225  24.977  1.479   1.00 47.99  ? 46  SER A CB  1 
ATOM 155  O OG  . SER A 1 21  ? -94.273  23.579  1.261   1.00 67.32  ? 46  SER A OG  1 
ATOM 156  N N   . ALA A 1 22  ? -93.161  26.226  -1.226  1.00 51.64  ? 47  ALA A N   1 
ATOM 157  C CA  . ALA A 1 22  ? -92.159  25.910  -2.242  1.00 46.49  ? 47  ALA A CA  1 
ATOM 158  C C   . ALA A 1 22  ? -90.854  26.527  -1.738  1.00 44.13  ? 47  ALA A C   1 
ATOM 159  O O   . ALA A 1 22  ? -90.596  27.716  -1.937  1.00 44.67  ? 47  ALA A O   1 
ATOM 160  C CB  . ALA A 1 22  ? -92.546  26.432  -3.616  1.00 47.75  ? 47  ALA A CB  1 
ATOM 161  N N   . LEU A 1 23  ? -90.050  25.712  -1.069  1.00 36.79  ? 48  LEU A N   1 
ATOM 162  C CA  . LEU A 1 23  ? -88.867  26.198  -0.377  1.00 54.14  ? 48  LEU A CA  1 
ATOM 163  C C   . LEU A 1 23  ? -87.624  25.843  -1.175  1.00 47.52  ? 48  LEU A C   1 
ATOM 164  O O   . LEU A 1 23  ? -87.443  24.686  -1.568  1.00 51.68  ? 48  LEU A O   1 
ATOM 165  C CB  . LEU A 1 23  ? -88.772  25.612  1.035   1.00 58.99  ? 48  LEU A CB  1 
ATOM 166  C CG  . LEU A 1 23  ? -89.980  25.826  1.950   1.00 51.15  ? 48  LEU A CG  1 
ATOM 167  C CD1 . LEU A 1 23  ? -89.646  25.406  3.371   1.00 40.29  ? 48  LEU A CD1 1 
ATOM 168  C CD2 . LEU A 1 23  ? -90.464  27.273  1.904   1.00 51.09  ? 48  LEU A CD2 1 
ATOM 169  N N   . ARG A 1 24  ? -86.774  26.840  -1.411  1.00 47.17  ? 49  ARG A N   1 
ATOM 170  C CA  . ARG A 1 24  ? -85.479  26.603  -2.038  1.00 46.88  ? 49  ARG A CA  1 
ATOM 171  C C   . ARG A 1 24  ? -84.556  25.922  -1.038  1.00 56.44  ? 49  ARG A C   1 
ATOM 172  O O   . ARG A 1 24  ? -84.097  26.547  -0.077  1.00 51.02  ? 49  ARG A O   1 
ATOM 173  C CB  . ARG A 1 24  ? -84.868  27.912  -2.520  1.00 44.98  ? 49  ARG A CB  1 
ATOM 174  C CG  . ARG A 1 24  ? -83.854  27.712  -3.619  1.00 48.48  ? 49  ARG A CG  1 
ATOM 175  C CD  . ARG A 1 24  ? -82.714  28.705  -3.529  1.00 53.30  ? 49  ARG A CD  1 
ATOM 176  N NE  . ARG A 1 24  ? -82.213  28.883  -2.171  1.00 48.96  ? 49  ARG A NE  1 
ATOM 177  C CZ  . ARG A 1 24  ? -81.311  28.098  -1.599  1.00 50.10  ? 49  ARG A CZ  1 
ATOM 178  N NH1 . ARG A 1 24  ? -80.810  27.048  -2.229  1.00 58.65  ? 49  ARG A NH1 1 
ATOM 179  N NH2 . ARG A 1 24  ? -80.898  28.375  -0.365  1.00 53.60  ? 49  ARG A NH2 1 
ATOM 180  N N   . THR A 1 25  ? -84.284  24.637  -1.262  1.00 51.60  ? 50  THR A N   1 
ATOM 181  C CA  . THR A 1 25  ? -83.445  23.858  -0.369  1.00 45.59  ? 50  THR A CA  1 
ATOM 182  C C   . THR A 1 25  ? -82.074  23.541  -0.941  1.00 48.86  ? 50  THR A C   1 
ATOM 183  O O   . THR A 1 25  ? -81.176  23.169  -0.179  1.00 64.54  ? 50  THR A O   1 
ATOM 184  C CB  . THR A 1 25  ? -84.147  22.544  -0.001  1.00 56.22  ? 50  THR A CB  1 
ATOM 185  O OG1 . THR A 1 25  ? -84.383  21.780  -1.191  1.00 45.13  ? 50  THR A OG1 1 
ATOM 186  C CG2 . THR A 1 25  ? -85.472  22.830  0.688   1.00 49.11  ? 50  THR A CG2 1 
ATOM 187  N N   . GLY A 1 26  ? -81.887  23.682  -2.249  1.00 59.80  ? 51  GLY A N   1 
ATOM 188  C CA  . GLY A 1 26  ? -80.621  23.365  -2.871  1.00 64.01  ? 51  GLY A CA  1 
ATOM 189  C C   . GLY A 1 26  ? -80.397  24.224  -4.095  1.00 52.09  ? 51  GLY A C   1 
ATOM 190  O O   . GLY A 1 26  ? -81.206  25.089  -4.434  1.00 45.17  ? 51  GLY A O   1 
ATOM 191  N N   . TRP A 1 27  ? -79.268  23.974  -4.754  1.00 51.64  ? 52  TRP A N   1 
ATOM 192  C CA  . TRP A 1 27  ? -78.876  24.674  -5.966  1.00 35.16  ? 52  TRP A CA  1 
ATOM 193  C C   . TRP A 1 27  ? -78.502  23.656  -7.027  1.00 43.11  ? 52  TRP A C   1 
ATOM 194  O O   . TRP A 1 27  ? -77.780  22.695  -6.744  1.00 52.97  ? 52  TRP A O   1 
ATOM 195  C CB  . TRP A 1 27  ? -77.683  25.596  -5.721  1.00 41.80  ? 52  TRP A CB  1 
ATOM 196  C CG  . TRP A 1 27  ? -77.970  26.769  -4.844  1.00 47.53  ? 52  TRP A CG  1 
ATOM 197  C CD1 . TRP A 1 27  ? -77.482  26.989  -3.591  1.00 46.82  ? 52  TRP A CD1 1 
ATOM 198  C CD2 . TRP A 1 27  ? -78.786  27.903  -5.162  1.00 49.83  ? 52  TRP A CD2 1 
ATOM 199  N NE1 . TRP A 1 27  ? -77.951  28.184  -3.103  1.00 58.83  ? 52  TRP A NE1 1 
ATOM 200  C CE2 . TRP A 1 27  ? -78.753  28.765  -4.049  1.00 43.90  ? 52  TRP A CE2 1 
ATOM 201  C CE3 . TRP A 1 27  ? -79.546  28.270  -6.276  1.00 43.71  ? 52  TRP A CE3 1 
ATOM 202  C CZ2 . TRP A 1 27  ? -79.448  29.970  -4.019  1.00 43.80  ? 52  TRP A CZ2 1 
ATOM 203  C CZ3 . TRP A 1 27  ? -80.233  29.468  -6.243  1.00 46.03  ? 52  TRP A CZ3 1 
ATOM 204  C CH2 . TRP A 1 27  ? -80.177  30.304  -5.125  1.00 44.35  ? 52  TRP A CH2 1 
ATOM 205  N N   . TYR A 1 28  ? -78.988  23.871  -8.246  1.00 44.84  ? 53  TYR A N   1 
ATOM 206  C CA  . TYR A 1 28  ? -78.555  23.115  -9.411  1.00 45.00  ? 53  TYR A CA  1 
ATOM 207  C C   . TYR A 1 28  ? -77.857  24.068  -10.371 1.00 49.66  ? 53  TYR A C   1 
ATOM 208  O O   . TYR A 1 28  ? -78.417  25.108  -10.732 1.00 57.86  ? 53  TYR A O   1 
ATOM 209  C CB  . TYR A 1 28  ? -79.731  22.425  -10.103 1.00 51.96  ? 53  TYR A CB  1 
ATOM 210  C CG  . TYR A 1 28  ? -79.326  21.673  -11.351 1.00 66.53  ? 53  TYR A CG  1 
ATOM 211  C CD1 . TYR A 1 28  ? -78.685  20.445  -11.264 1.00 57.21  ? 53  TYR A CD1 1 
ATOM 212  C CD2 . TYR A 1 28  ? -79.573  22.196  -12.613 1.00 52.65  ? 53  TYR A CD2 1 
ATOM 213  C CE1 . TYR A 1 28  ? -78.309  19.753  -12.394 1.00 51.86  ? 53  TYR A CE1 1 
ATOM 214  C CE2 . TYR A 1 28  ? -79.200  21.508  -13.754 1.00 75.13  ? 53  TYR A CE2 1 
ATOM 215  C CZ  . TYR A 1 28  ? -78.566  20.287  -13.636 1.00 63.43  ? 53  TYR A CZ  1 
ATOM 216  O OH  . TYR A 1 28  ? -78.187  19.595  -14.763 1.00 60.81  ? 53  TYR A OH  1 
ATOM 217  N N   . THR A 1 29  ? -76.641  23.716  -10.780 1.00 50.87  ? 54  THR A N   1 
ATOM 218  C CA  . THR A 1 29  ? -75.811  24.569  -11.621 1.00 61.73  ? 54  THR A CA  1 
ATOM 219  C C   . THR A 1 29  ? -75.713  23.988  -13.027 1.00 46.31  ? 54  THR A C   1 
ATOM 220  O O   . THR A 1 29  ? -75.393  22.807  -13.192 1.00 58.42  ? 54  THR A O   1 
ATOM 221  C CB  . THR A 1 29  ? -74.413  24.730  -11.015 1.00 57.09  ? 54  THR A CB  1 
ATOM 222  O OG1 . THR A 1 29  ? -73.773  23.449  -10.933 1.00 62.33  ? 54  THR A OG1 1 
ATOM 223  C CG2 . THR A 1 29  ? -74.506  25.329  -9.622  1.00 48.46  ? 54  THR A CG2 1 
ATOM 224  N N   . SER A 1 30  ? -75.980  24.820  -14.033 1.00 53.00  ? 55  SER A N   1 
ATOM 225  C CA  . SER A 1 30  ? -75.883  24.430  -15.434 1.00 54.84  ? 55  SER A CA  1 
ATOM 226  C C   . SER A 1 30  ? -74.943  25.379  -16.165 1.00 43.67  ? 55  SER A C   1 
ATOM 227  O O   . SER A 1 30  ? -74.862  26.566  -15.843 1.00 44.73  ? 55  SER A O   1 
ATOM 228  C CB  . SER A 1 30  ? -77.248  24.449  -16.128 1.00 43.08  ? 55  SER A CB  1 
ATOM 229  O OG  . SER A 1 30  ? -77.851  25.726  -16.012 1.00 51.29  ? 55  SER A OG  1 
ATOM 230  N N   . VAL A 1 31  ? -74.246  24.852  -17.166 1.00 39.62  ? 56  VAL A N   1 
ATOM 231  C CA  . VAL A 1 31  ? -73.266  25.619  -17.927 1.00 56.91  ? 56  VAL A CA  1 
ATOM 232  C C   . VAL A 1 31  ? -73.901  26.064  -19.240 1.00 46.72  ? 56  VAL A C   1 
ATOM 233  O O   . VAL A 1 31  ? -74.295  25.232  -20.066 1.00 44.10  ? 56  VAL A O   1 
ATOM 234  C CB  . VAL A 1 31  ? -71.989  24.802  -18.177 1.00 44.31  ? 56  VAL A CB  1 
ATOM 235  C CG1 . VAL A 1 31  ? -71.054  25.551  -19.114 1.00 44.20  ? 56  VAL A CG1 1 
ATOM 236  C CG2 . VAL A 1 31  ? -71.296  24.505  -16.861 1.00 34.19  ? 56  VAL A CG2 1 
ATOM 237  N N   . ILE A 1 32  ? -73.993  27.377  -19.438 1.00 46.82  ? 57  ILE A N   1 
ATOM 238  C CA  . ILE A 1 32  ? -74.528  27.967  -20.661 1.00 54.23  ? 57  ILE A CA  1 
ATOM 239  C C   . ILE A 1 32  ? -73.364  28.525  -21.467 1.00 50.28  ? 57  ILE A C   1 
ATOM 240  O O   . ILE A 1 32  ? -72.569  29.322  -20.952 1.00 43.90  ? 57  ILE A O   1 
ATOM 241  C CB  . ILE A 1 32  ? -75.565  29.061  -20.357 1.00 46.79  ? 57  ILE A CB  1 
ATOM 242  C CG1 . ILE A 1 32  ? -76.576  28.564  -19.325 1.00 50.11  ? 57  ILE A CG1 1 
ATOM 243  C CG2 . ILE A 1 32  ? -76.279  29.481  -21.627 1.00 39.08  ? 57  ILE A CG2 1 
ATOM 244  C CD1 . ILE A 1 32  ? -77.326  27.329  -19.764 1.00 50.83  ? 57  ILE A CD1 1 
ATOM 245  N N   . THR A 1 33  ? -73.264  28.111  -22.727 1.00 50.59  ? 58  THR A N   1 
ATOM 246  C CA  . THR A 1 33  ? -72.131  28.461  -23.569 1.00 50.82  ? 58  THR A CA  1 
ATOM 247  C C   . THR A 1 33  ? -72.589  29.201  -24.818 1.00 44.66  ? 58  THR A C   1 
ATOM 248  O O   . THR A 1 33  ? -73.692  28.978  -25.331 1.00 45.37  ? 58  THR A O   1 
ATOM 249  C CB  . THR A 1 33  ? -71.330  27.219  -23.994 1.00 54.33  ? 58  THR A CB  1 
ATOM 250  O OG1 . THR A 1 33  ? -72.095  26.450  -24.931 1.00 57.98  ? 58  THR A OG1 1 
ATOM 251  C CG2 . THR A 1 33  ? -70.988  26.355  -22.790 1.00 38.63  ? 58  THR A CG2 1 
ATOM 252  N N   . ILE A 1 34  ? -71.728  30.097  -25.293 1.00 44.00  ? 59  ILE A N   1 
ATOM 253  C CA  . ILE A 1 34  ? -71.876  30.738  -26.594 1.00 45.69  ? 59  ILE A CA  1 
ATOM 254  C C   . ILE A 1 34  ? -70.580  30.506  -27.355 1.00 44.10  ? 59  ILE A C   1 
ATOM 255  O O   . ILE A 1 34  ? -69.505  30.891  -26.880 1.00 52.02  ? 59  ILE A O   1 
ATOM 256  C CB  . ILE A 1 34  ? -72.171  32.242  -26.474 1.00 50.61  ? 59  ILE A CB  1 
ATOM 257  C CG1 . ILE A 1 34  ? -73.469  32.480  -25.702 1.00 54.83  ? 59  ILE A CG1 1 
ATOM 258  C CG2 . ILE A 1 34  ? -72.264  32.880  -27.848 1.00 55.50  ? 59  ILE A CG2 1 
ATOM 259  C CD1 . ILE A 1 34  ? -73.728  33.937  -25.396 1.00 35.23  ? 59  ILE A CD1 1 
ATOM 260  N N   . GLU A 1 35  ? -70.673  29.869  -28.520 1.00 59.25  ? 60  GLU A N   1 
ATOM 261  C CA  . GLU A 1 35  ? -69.488  29.625  -29.330 1.00 64.95  ? 60  GLU A CA  1 
ATOM 262  C C   . GLU A 1 35  ? -69.078  30.913  -30.030 1.00 48.69  ? 60  GLU A C   1 
ATOM 263  O O   . GLU A 1 35  ? -69.909  31.584  -30.651 1.00 45.30  ? 60  GLU A O   1 
ATOM 264  C CB  . GLU A 1 35  ? -69.741  28.513  -30.348 1.00 60.30  ? 60  GLU A CB  1 
ATOM 265  C CG  . GLU A 1 35  ? -68.496  27.694  -30.679 1.00 69.13  ? 60  GLU A CG  1 
ATOM 266  C CD  . GLU A 1 35  ? -68.782  26.524  -31.609 1.00 111.22 ? 60  GLU A CD  1 
ATOM 267  O OE1 . GLU A 1 35  ? -69.910  26.444  -32.144 1.00 109.67 ? 60  GLU A OE1 1 
ATOM 268  O OE2 . GLU A 1 35  ? -67.875  25.686  -31.811 1.00 115.79 ? 60  GLU A OE2 1 
ATOM 269  N N   . LEU A 1 36  ? -67.802  31.266  -29.914 1.00 54.34  ? 61  LEU A N   1 
ATOM 270  C CA  . LEU A 1 36  ? -67.267  32.502  -30.460 1.00 59.41  ? 61  LEU A CA  1 
ATOM 271  C C   . LEU A 1 36  ? -66.311  32.212  -31.610 1.00 70.85  ? 61  LEU A C   1 
ATOM 272  O O   . LEU A 1 36  ? -65.784  31.105  -31.750 1.00 76.78  ? 61  LEU A O   1 
ATOM 273  C CB  . LEU A 1 36  ? -66.540  33.311  -29.383 1.00 42.74  ? 61  LEU A CB  1 
ATOM 274  C CG  . LEU A 1 36  ? -67.357  33.779  -28.182 1.00 42.32  ? 61  LEU A CG  1 
ATOM 275  C CD1 . LEU A 1 36  ? -66.454  34.521  -27.218 1.00 35.76  ? 61  LEU A CD1 1 
ATOM 276  C CD2 . LEU A 1 36  ? -68.523  34.654  -28.616 1.00 36.88  ? 61  LEU A CD2 1 
ATOM 277  N N   . SER A 1 37  ? -66.085  33.236  -32.428 1.00 67.50  ? 62  SER A N   1 
ATOM 278  C CA  . SER A 1 37  ? -65.207  33.150  -33.586 1.00 66.31  ? 62  SER A CA  1 
ATOM 279  C C   . SER A 1 37  ? -63.957  33.982  -33.338 1.00 68.95  ? 62  SER A C   1 
ATOM 280  O O   . SER A 1 37  ? -64.050  35.156  -32.966 1.00 77.31  ? 62  SER A O   1 
ATOM 281  C CB  . SER A 1 37  ? -65.921  33.633  -34.850 1.00 84.22  ? 62  SER A CB  1 
ATOM 282  O OG  . SER A 1 37  ? -65.002  33.842  -35.908 1.00 96.83  ? 62  SER A OG  1 
ATOM 283  N N   . ASN A 1 38  ? -62.794  33.374  -33.549 1.00 80.32  ? 63  ASN A N   1 
ATOM 284  C CA  . ASN A 1 38  ? -61.513  34.062  -33.407 1.00 83.43  ? 63  ASN A CA  1 
ATOM 285  C C   . ASN A 1 38  ? -61.194  34.739  -34.733 1.00 100.11 ? 63  ASN A C   1 
ATOM 286  O O   . ASN A 1 38  ? -60.807  34.082  -35.703 1.00 106.65 ? 63  ASN A O   1 
ATOM 287  C CB  . ASN A 1 38  ? -60.422  33.079  -32.999 1.00 89.02  ? 63  ASN A CB  1 
ATOM 288  C CG  . ASN A 1 38  ? -59.630  33.553  -31.802 1.00 95.64  ? 63  ASN A CG  1 
ATOM 289  O OD1 . ASN A 1 38  ? -59.599  34.745  -31.498 1.00 113.28 ? 63  ASN A OD1 1 
ATOM 290  N ND2 . ASN A 1 38  ? -58.992  32.618  -31.107 1.00 99.97  ? 63  ASN A ND2 1 
ATOM 291  N N   . ILE A 1 39  ? -61.360  36.059  -34.781 1.00 98.55  ? 64  ILE A N   1 
ATOM 292  C CA  . ILE A 1 39  ? -61.116  36.841  -35.987 1.00 106.93 ? 64  ILE A CA  1 
ATOM 293  C C   . ILE A 1 39  ? -60.051  37.887  -35.691 1.00 116.69 ? 64  ILE A C   1 
ATOM 294  O O   . ILE A 1 39  ? -60.033  38.485  -34.609 1.00 125.24 ? 64  ILE A O   1 
ATOM 295  C CB  . ILE A 1 39  ? -62.404  37.504  -36.522 1.00 90.84  ? 64  ILE A CB  1 
ATOM 296  C CG1 . ILE A 1 39  ? -63.009  38.452  -35.484 1.00 95.41  ? 64  ILE A CG1 1 
ATOM 297  C CG2 . ILE A 1 39  ? -63.418  36.449  -36.937 1.00 90.97  ? 64  ILE A CG2 1 
ATOM 298  C CD1 . ILE A 1 39  ? -64.153  39.279  -36.019 1.00 77.41  ? 64  ILE A CD1 1 
ATOM 299  N N   . LYS A 1 40  ? -59.152  38.083  -36.643 1.00 112.97 ? 65  LYS A N   1 
ATOM 300  C CA  . LYS A 1 40  ? -58.101  39.091  -36.552 1.00 120.19 ? 65  LYS A CA  1 
ATOM 301  C C   . LYS A 1 40  ? -58.052  40.008  -37.763 1.00 131.98 ? 65  LYS A C   1 
ATOM 302  O O   . LYS A 1 40  ? -57.802  41.206  -37.610 1.00 129.04 ? 65  LYS A O   1 
ATOM 303  C CB  . LYS A 1 40  ? -56.732  38.412  -36.366 1.00 125.21 ? 65  LYS A CB  1 
ATOM 304  C CG  . LYS A 1 40  ? -55.693  39.287  -35.682 1.00 119.29 ? 65  LYS A CG  1 
ATOM 305  C CD  . LYS A 1 40  ? -54.289  38.728  -35.863 1.00 114.54 ? 65  LYS A CD  1 
ATOM 306  C CE  . LYS A 1 40  ? -53.252  39.615  -35.192 1.00 119.54 ? 65  LYS A CE  1 
ATOM 307  N NZ  . LYS A 1 40  ? -53.397  41.041  -35.595 1.00 124.23 ? 65  LYS A NZ  1 
ATOM 308  N N   . GLU A 1 41  ? -58.292  39.479  -38.961 1.00 142.97 ? 66  GLU A N   1 
ATOM 309  C CA  . GLU A 1 41  ? -58.163  40.252  -40.194 1.00 135.31 ? 66  GLU A CA  1 
ATOM 310  C C   . GLU A 1 41  ? -59.461  41.006  -40.450 1.00 135.29 ? 66  GLU A C   1 
ATOM 311  O O   . GLU A 1 41  ? -60.415  40.455  -41.005 1.00 131.76 ? 66  GLU A O   1 
ATOM 312  C CB  . GLU A 1 41  ? -57.817  39.347  -41.371 1.00 137.64 ? 66  GLU A CB  1 
ATOM 313  C CG  . GLU A 1 41  ? -56.428  38.739  -41.315 1.00 146.49 ? 66  GLU A CG  1 
ATOM 314  C CD  . GLU A 1 41  ? -56.162  37.804  -42.479 1.00 152.70 ? 66  GLU A CD  1 
ATOM 315  O OE1 . GLU A 1 41  ? -57.118  37.484  -43.216 1.00 154.18 ? 66  GLU A OE1 1 
ATOM 316  O OE2 . GLU A 1 41  ? -54.996  37.392  -42.660 1.00 153.76 ? 66  GLU A OE2 1 
ATOM 317  N N   . ASN A 1 42  ? -59.497  42.272  -40.042 1.00 133.10 ? 67  ASN A N   1 
ATOM 318  C CA  . ASN A 1 42  ? -60.529  43.197  -40.484 1.00 141.98 ? 67  ASN A CA  1 
ATOM 319  C C   . ASN A 1 42  ? -60.119  43.948  -41.745 1.00 140.27 ? 67  ASN A C   1 
ATOM 320  O O   . ASN A 1 42  ? -60.710  44.987  -42.061 1.00 136.82 ? 67  ASN A O   1 
ATOM 321  C CB  . ASN A 1 42  ? -60.891  44.167  -39.352 1.00 134.88 ? 67  ASN A CB  1 
ATOM 322  C CG  . ASN A 1 42  ? -59.709  45.002  -38.877 1.00 139.32 ? 67  ASN A CG  1 
ATOM 323  O OD1 . ASN A 1 42  ? -58.819  45.356  -39.650 1.00 146.42 ? 67  ASN A OD1 1 
ATOM 324  N ND2 . ASN A 1 42  ? -59.702  45.321  -37.588 1.00 139.21 ? 67  ASN A ND2 1 
ATOM 325  N N   . LYS A 1 43  ? -59.119  43.439  -42.463 1.00 140.99 ? 68  LYS A N   1 
ATOM 326  C CA  . LYS A 1 43  ? -58.619  44.089  -43.668 1.00 138.56 ? 68  LYS A CA  1 
ATOM 327  C C   . LYS A 1 43  ? -59.713  44.098  -44.728 1.00 135.52 ? 68  LYS A C   1 
ATOM 328  O O   . LYS A 1 43  ? -60.212  43.041  -45.130 1.00 143.28 ? 68  LYS A O   1 
ATOM 329  C CB  . LYS A 1 43  ? -57.369  43.360  -44.168 1.00 138.09 ? 68  LYS A CB  1 
ATOM 330  C CG  . LYS A 1 43  ? -57.120  43.347  -45.687 1.00 135.26 ? 68  LYS A CG  1 
ATOM 331  C CD  . LYS A 1 43  ? -57.009  44.741  -46.302 1.00 135.22 ? 68  LYS A CD  1 
ATOM 332  C CE  . LYS A 1 43  ? -56.349  44.686  -47.671 1.00 130.44 ? 68  LYS A CE  1 
ATOM 333  N NZ  . LYS A 1 43  ? -56.956  45.649  -48.630 1.00 121.34 ? 68  LYS A NZ  1 
ATOM 334  N N   . CYS A 1 44  ? -60.089  45.295  -45.171 1.00 126.85 ? 69  CYS A N   1 
ATOM 335  C CA  . CYS A 1 44  ? -61.050  45.445  -46.259 1.00 135.10 ? 69  CYS A CA  1 
ATOM 336  C C   . CYS A 1 44  ? -60.922  46.852  -46.816 1.00 146.24 ? 69  CYS A C   1 
ATOM 337  O O   . CYS A 1 44  ? -61.191  47.824  -46.102 1.00 128.85 ? 69  CYS A O   1 
ATOM 338  C CB  . CYS A 1 44  ? -62.475  45.182  -45.778 1.00 136.68 ? 69  CYS A CB  1 
ATOM 339  S SG  . CYS A 1 44  ? -63.742  45.757  -46.928 1.00 163.79 ? 69  CYS A SG  1 
ATOM 340  N N   . ASN A 1 45  ? -60.510  46.962  -48.075 1.00 151.90 ? 70  ASN A N   1 
ATOM 341  C CA  . ASN A 1 45  ? -60.471  48.248  -48.771 1.00 146.41 ? 70  ASN A CA  1 
ATOM 342  C C   . ASN A 1 45  ? -61.827  48.569  -49.393 1.00 150.10 ? 70  ASN A C   1 
ATOM 343  O O   . ASN A 1 45  ? -61.950  48.826  -50.589 1.00 158.35 ? 70  ASN A O   1 
ATOM 344  C CB  . ASN A 1 45  ? -59.367  48.240  -49.823 1.00 149.02 ? 70  ASN A CB  1 
ATOM 345  C CG  . ASN A 1 45  ? -59.084  49.620  -50.389 1.00 153.43 ? 70  ASN A CG  1 
ATOM 346  O OD1 . ASN A 1 45  ? -58.526  50.481  -49.709 1.00 150.23 ? 70  ASN A OD1 1 
ATOM 347  N ND2 . ASN A 1 45  ? -59.470  49.835  -51.642 1.00 150.89 ? 70  ASN A ND2 1 
ATOM 348  N N   . GLY A 1 46  ? -62.867  48.548  -48.564 1.00 142.12 ? 71  GLY A N   1 
ATOM 349  C CA  . GLY A 1 46  ? -64.232  48.754  -49.012 1.00 134.05 ? 71  GLY A CA  1 
ATOM 350  C C   . GLY A 1 46  ? -64.812  50.034  -48.424 1.00 124.33 ? 71  GLY A C   1 
ATOM 351  O O   . GLY A 1 46  ? -64.750  50.254  -47.214 1.00 121.60 ? 71  GLY A O   1 
ATOM 352  N N   . THR A 1 47  ? -65.366  50.862  -49.304 1.00 119.01 ? 72  THR A N   1 
ATOM 353  C CA  . THR A 1 47  ? -66.058  52.080  -48.907 1.00 118.18 ? 72  THR A CA  1 
ATOM 354  C C   . THR A 1 47  ? -67.571  51.938  -48.966 1.00 118.63 ? 72  THR A C   1 
ATOM 355  O O   . THR A 1 47  ? -68.282  52.887  -48.620 1.00 111.98 ? 72  THR A O   1 
ATOM 356  C CB  . THR A 1 47  ? -65.620  53.255  -49.789 1.00 128.74 ? 72  THR A CB  1 
ATOM 357  O OG1 . THR A 1 47  ? -66.361  54.428  -49.429 1.00 131.24 ? 72  THR A OG1 1 
ATOM 358  C CG2 . THR A 1 47  ? -65.868  52.938  -51.259 1.00 113.08 ? 72  THR A CG2 1 
ATOM 359  N N   . ASP A 1 48  ? -68.076  50.784  -49.401 1.00 116.62 ? 73  ASP A N   1 
ATOM 360  C CA  . ASP A 1 48  ? -69.515  50.569  -49.460 1.00 107.58 ? 73  ASP A CA  1 
ATOM 361  C C   . ASP A 1 48  ? -70.114  50.684  -48.064 1.00 105.14 ? 73  ASP A C   1 
ATOM 362  O O   . ASP A 1 48  ? -69.520  50.245  -47.075 1.00 103.77 ? 73  ASP A O   1 
ATOM 363  C CB  . ASP A 1 48  ? -69.820  49.196  -50.065 1.00 111.02 ? 73  ASP A CB  1 
ATOM 364  C CG  . ASP A 1 48  ? -71.311  48.917  -50.173 1.00 116.69 ? 73  ASP A CG  1 
ATOM 365  O OD1 . ASP A 1 48  ? -72.102  49.885  -50.183 1.00 119.27 ? 73  ASP A OD1 1 
ATOM 366  O OD2 . ASP A 1 48  ? -71.690  47.729  -50.253 1.00 114.35 ? 73  ASP A OD2 1 
ATOM 367  N N   . ALA A 1 49  ? -71.295  51.299  -47.987 1.00 96.90  ? 74  ALA A N   1 
ATOM 368  C CA  . ALA A 1 49  ? -71.917  51.542  -46.691 1.00 95.29  ? 74  ALA A CA  1 
ATOM 369  C C   . ALA A 1 49  ? -72.291  50.235  -46.001 1.00 94.28  ? 74  ALA A C   1 
ATOM 370  O O   . ALA A 1 49  ? -72.206  50.127  -44.771 1.00 90.71  ? 74  ALA A O   1 
ATOM 371  C CB  . ALA A 1 49  ? -73.139  52.439  -46.862 1.00 90.32  ? 74  ALA A CB  1 
ATOM 372  N N   . LYS A 1 50  ? -72.716  49.234  -46.775 1.00 87.22  ? 75  LYS A N   1 
ATOM 373  C CA  . LYS A 1 50  ? -72.960  47.913  -46.208 1.00 86.22  ? 75  LYS A CA  1 
ATOM 374  C C   . LYS A 1 50  ? -71.693  47.365  -45.562 1.00 84.84  ? 75  LYS A C   1 
ATOM 375  O O   . LYS A 1 50  ? -71.737  46.787  -44.467 1.00 88.82  ? 75  LYS A O   1 
ATOM 376  C CB  . LYS A 1 50  ? -73.468  46.975  -47.304 1.00 86.24  ? 75  LYS A CB  1 
ATOM 377  C CG  . LYS A 1 50  ? -74.912  47.239  -47.693 1.00 101.45 ? 75  LYS A CG  1 
ATOM 378  C CD  . LYS A 1 50  ? -75.726  45.982  -47.916 1.00 110.44 ? 75  LYS A CD  1 
ATOM 379  C CE  . LYS A 1 50  ? -75.285  45.262  -49.173 1.00 122.36 ? 75  LYS A CE  1 
ATOM 380  N NZ  . LYS A 1 50  ? -75.585  46.016  -50.418 1.00 111.61 ? 75  LYS A NZ  1 
ATOM 381  N N   . VAL A 1 51  ? -70.549  47.565  -46.219 1.00 79.78  ? 76  VAL A N   1 
ATOM 382  C CA  . VAL A 1 51  ? -69.273  47.128  -45.664 1.00 91.59  ? 76  VAL A CA  1 
ATOM 383  C C   . VAL A 1 51  ? -68.972  47.867  -44.363 1.00 79.37  ? 76  VAL A C   1 
ATOM 384  O O   . VAL A 1 51  ? -68.496  47.268  -43.392 1.00 76.36  ? 76  VAL A O   1 
ATOM 385  C CB  . VAL A 1 51  ? -68.153  47.311  -46.706 1.00 97.34  ? 76  VAL A CB  1 
ATOM 386  C CG1 . VAL A 1 51  ? -66.794  47.419  -46.029 1.00 106.21 ? 76  VAL A CG1 1 
ATOM 387  C CG2 . VAL A 1 51  ? -68.171  46.164  -47.707 1.00 108.01 ? 76  VAL A CG2 1 
ATOM 388  N N   . LYS A 1 52  ? -69.241  49.177  -44.322 1.00 76.67  ? 77  LYS A N   1 
ATOM 389  C CA  . LYS A 1 52  ? -68.999  49.943  -43.101 1.00 78.85  ? 77  LYS A CA  1 
ATOM 390  C C   . LYS A 1 52  ? -69.882  49.460  -41.956 1.00 74.45  ? 77  LYS A C   1 
ATOM 391  O O   . LYS A 1 52  ? -69.433  49.382  -40.807 1.00 69.83  ? 77  LYS A O   1 
ATOM 392  C CB  . LYS A 1 52  ? -69.227  51.434  -43.353 1.00 80.74  ? 77  LYS A CB  1 
ATOM 393  C CG  . LYS A 1 52  ? -68.371  52.028  -44.458 1.00 97.81  ? 77  LYS A CG  1 
ATOM 394  C CD  . LYS A 1 52  ? -69.019  53.279  -45.040 1.00 110.40 ? 77  LYS A CD  1 
ATOM 395  C CE  . LYS A 1 52  ? -68.036  54.442  -45.116 1.00 101.30 ? 77  LYS A CE  1 
ATOM 396  N NZ  . LYS A 1 52  ? -67.108  54.314  -46.276 1.00 105.29 ? 77  LYS A NZ  1 
ATOM 397  N N   . LEU A 1 53  ? -71.146  49.141  -42.248 1.00 75.01  ? 78  LEU A N   1 
ATOM 398  C CA  . LEU A 1 53  ? -72.033  48.614  -41.216 1.00 61.45  ? 78  LEU A CA  1 
ATOM 399  C C   . LEU A 1 53  ? -71.538  47.272  -40.695 1.00 63.96  ? 78  LEU A C   1 
ATOM 400  O O   . LEU A 1 53  ? -71.537  47.029  -39.479 1.00 81.72  ? 78  LEU A O   1 
ATOM 401  C CB  . LEU A 1 53  ? -73.452  48.478  -41.765 1.00 63.38  ? 78  LEU A CB  1 
ATOM 402  C CG  . LEU A 1 53  ? -74.114  49.788  -42.188 1.00 72.98  ? 78  LEU A CG  1 
ATOM 403  C CD1 . LEU A 1 53  ? -75.591  49.577  -42.454 1.00 89.17  ? 78  LEU A CD1 1 
ATOM 404  C CD2 . LEU A 1 53  ? -73.903  50.851  -41.126 1.00 76.70  ? 78  LEU A CD2 1 
ATOM 405  N N   . ILE A 1 54  ? -71.115  46.384  -41.600 1.00 50.73  ? 79  ILE A N   1 
ATOM 406  C CA  . ILE A 1 54  ? -70.561  45.106  -41.162 1.00 57.39  ? 79  ILE A CA  1 
ATOM 407  C C   . ILE A 1 54  ? -69.330  45.333  -40.296 1.00 59.73  ? 79  ILE A C   1 
ATOM 408  O O   . ILE A 1 54  ? -69.142  44.661  -39.274 1.00 77.46  ? 79  ILE A O   1 
ATOM 409  C CB  . ILE A 1 54  ? -70.243  44.201  -42.368 1.00 57.44  ? 79  ILE A CB  1 
ATOM 410  C CG1 . ILE A 1 54  ? -71.525  43.808  -43.100 1.00 62.34  ? 79  ILE A CG1 1 
ATOM 411  C CG2 . ILE A 1 54  ? -69.494  42.960  -41.917 1.00 50.64  ? 79  ILE A CG2 1 
ATOM 412  C CD1 . ILE A 1 54  ? -71.323  43.503  -44.574 1.00 80.01  ? 79  ILE A CD1 1 
ATOM 413  N N   . LYS A 1 55  ? -68.474  46.281  -40.686 1.00 58.79  ? 80  LYS A N   1 
ATOM 414  C CA  . LYS A 1 55  ? -67.274  46.563  -39.905 1.00 61.34  ? 80  LYS A CA  1 
ATOM 415  C C   . LYS A 1 55  ? -67.631  47.076  -38.517 1.00 75.82  ? 80  LYS A C   1 
ATOM 416  O O   . LYS A 1 55  ? -67.007  46.686  -37.524 1.00 77.66  ? 80  LYS A O   1 
ATOM 417  C CB  . LYS A 1 55  ? -66.391  47.573  -40.638 1.00 61.14  ? 80  LYS A CB  1 
ATOM 418  C CG  . LYS A 1 55  ? -65.609  46.983  -41.803 1.00 90.86  ? 80  LYS A CG  1 
ATOM 419  C CD  . LYS A 1 55  ? -65.168  48.068  -42.774 1.00 99.88  ? 80  LYS A CD  1 
ATOM 420  C CE  . LYS A 1 55  ? -63.856  47.717  -43.455 1.00 107.51 ? 80  LYS A CE  1 
ATOM 421  N NZ  . LYS A 1 55  ? -63.735  48.388  -44.780 1.00 116.02 ? 80  LYS A NZ  1 
ATOM 422  N N   . GLN A 1 56  ? -68.634  47.951  -38.430 1.00 65.61  ? 81  GLN A N   1 
ATOM 423  C CA  . GLN A 1 56  ? -69.063  48.453  -37.130 1.00 60.71  ? 81  GLN A CA  1 
ATOM 424  C C   . GLN A 1 56  ? -69.596  47.327  -36.253 1.00 70.36  ? 81  GLN A C   1 
ATOM 425  O O   . GLN A 1 56  ? -69.278  47.252  -35.059 1.00 68.98  ? 81  GLN A O   1 
ATOM 426  C CB  . GLN A 1 56  ? -70.122  49.538  -37.312 1.00 46.96  ? 81  GLN A CB  1 
ATOM 427  C CG  . GLN A 1 56  ? -69.562  50.875  -37.754 1.00 63.76  ? 81  GLN A CG  1 
ATOM 428  C CD  . GLN A 1 56  ? -70.605  51.743  -38.420 1.00 85.06  ? 81  GLN A CD  1 
ATOM 429  O OE1 . GLN A 1 56  ? -71.647  52.037  -37.833 1.00 82.28  ? 81  GLN A OE1 1 
ATOM 430  N NE2 . GLN A 1 56  ? -70.336  52.154  -39.654 1.00 98.67  ? 81  GLN A NE2 1 
ATOM 431  N N   . GLU A 1 57  ? -70.389  46.434  -36.832 1.00 62.98  ? 82  GLU A N   1 
ATOM 432  C CA  . GLU A 1 57  ? -71.012  45.380  -35.997 1.00 65.06  ? 82  GLU A CA  1 
ATOM 433  C C   . GLU A 1 57  ? -69.937  44.378  -35.576 1.00 65.73  ? 82  GLU A C   1 
ATOM 434  O O   . GLU A 1 57  ? -70.047  43.822  -34.479 1.00 68.05  ? 82  GLU A O   1 
ATOM 435  C CB  . GLU A 1 57  ? -72.160  44.715  -36.753 1.00 61.49  ? 82  GLU A CB  1 
ATOM 436  C CG  . GLU A 1 57  ? -73.095  43.924  -35.860 1.00 78.70  ? 82  GLU A CG  1 
ATOM 437  C CD  . GLU A 1 57  ? -73.730  44.720  -34.735 1.00 82.80  ? 82  GLU A CD  1 
ATOM 438  O OE1 . GLU A 1 57  ? -74.127  45.873  -34.981 1.00 89.44  ? 82  GLU A OE1 1 
ATOM 439  O OE2 . GLU A 1 57  ? -73.832  44.179  -33.618 1.00 85.00  ? 82  GLU A OE2 1 
ATOM 440  N N   . LEU A 1 58  ? -68.931  44.177  -36.417 1.00 57.75  ? 83  LEU A N   1 
ATOM 441  C CA  . LEU A 1 58  ? -67.834  43.241  -36.068 1.00 67.31  ? 83  LEU A CA  1 
ATOM 442  C C   . LEU A 1 58  ? -66.965  43.866  -34.976 1.00 63.80  ? 83  LEU A C   1 
ATOM 443  O O   . LEU A 1 58  ? -66.506  43.129  -34.096 1.00 56.74  ? 83  LEU A O   1 
ATOM 444  C CB  . LEU A 1 58  ? -67.023  42.927  -37.326 1.00 54.97  ? 83  LEU A CB  1 
ATOM 445  C CG  . LEU A 1 58  ? -67.475  41.687  -38.093 1.00 64.48  ? 83  LEU A CG  1 
ATOM 446  C CD1 . LEU A 1 58  ? -66.604  41.461  -39.317 1.00 66.00  ? 83  LEU A CD1 1 
ATOM 447  C CD2 . LEU A 1 58  ? -67.455  40.462  -37.194 1.00 49.83  ? 83  LEU A CD2 1 
ATOM 448  N N   . ASP A 1 59  ? -66.757  45.177  -35.037 1.00 63.66  ? 84  ASP A N   1 
ATOM 449  C CA  . ASP A 1 59  ? -65.982  45.874  -33.983 1.00 61.72  ? 84  ASP A CA  1 
ATOM 450  C C   . ASP A 1 59  ? -66.761  45.777  -32.675 1.00 64.35  ? 84  ASP A C   1 
ATOM 451  O O   . ASP A 1 59  ? -66.136  45.544  -31.635 1.00 60.09  ? 84  ASP A O   1 
ATOM 452  C CB  . ASP A 1 59  ? -65.706  47.322  -34.378 1.00 65.20  ? 84  ASP A CB  1 
ATOM 453  C CG  . ASP A 1 59  ? -64.602  47.461  -35.410 1.00 90.20  ? 84  ASP A CG  1 
ATOM 454  O OD1 . ASP A 1 59  ? -64.005  46.427  -35.767 1.00 101.24 ? 84  ASP A OD1 1 
ATOM 455  O OD2 . ASP A 1 59  ? -64.350  48.600  -35.846 1.00 89.96  ? 84  ASP A OD2 1 
ATOM 456  N N   . LYS A 1 60  ? -68.077  45.951  -32.735 1.00 62.04  ? 85  LYS A N   1 
ATOM 457  C CA  . LYS A 1 60  ? -68.870  45.766  -31.523 1.00 50.35  ? 85  LYS A CA  1 
ATOM 458  C C   . LYS A 1 60  ? -68.669  44.370  -30.946 1.00 62.54  ? 85  LYS A C   1 
ATOM 459  O O   . LYS A 1 60  ? -68.503  44.208  -29.730 1.00 71.94  ? 85  LYS A O   1 
ATOM 460  C CB  . LYS A 1 60  ? -70.350  46.005  -31.818 1.00 45.62  ? 85  LYS A CB  1 
ATOM 461  C CG  . LYS A 1 60  ? -70.736  47.461  -31.969 1.00 47.69  ? 85  LYS A CG  1 
ATOM 462  C CD  . LYS A 1 60  ? -72.248  47.620  -31.976 1.00 43.03  ? 85  LYS A CD  1 
ATOM 463  C CE  . LYS A 1 60  ? -72.706  48.459  -33.156 1.00 75.07  ? 85  LYS A CE  1 
ATOM 464  N NZ  . LYS A 1 60  ? -74.183  48.406  -33.331 1.00 78.06  ? 85  LYS A NZ  1 
ATOM 465  N N   . TYR A 1 61  ? -68.680  43.351  -31.808 1.00 56.31  ? 86  TYR A N   1 
ATOM 466  C CA  . TYR A 1 61  ? -68.465  41.979  -31.353 1.00 48.92  ? 86  TYR A CA  1 
ATOM 467  C C   . TYR A 1 61  ? -67.085  41.823  -30.715 1.00 61.01  ? 86  TYR A C   1 
ATOM 468  O O   . TYR A 1 61  ? -66.941  41.214  -29.644 1.00 64.95  ? 86  TYR A O   1 
ATOM 469  C CB  . TYR A 1 61  ? -68.639  41.020  -32.538 1.00 57.70  ? 86  TYR A CB  1 
ATOM 470  C CG  . TYR A 1 61  ? -68.099  39.620  -32.330 1.00 54.70  ? 86  TYR A CG  1 
ATOM 471  C CD1 . TYR A 1 61  ? -66.764  39.319  -32.581 1.00 55.02  ? 86  TYR A CD1 1 
ATOM 472  C CD2 . TYR A 1 61  ? -68.931  38.591  -31.909 1.00 50.63  ? 86  TYR A CD2 1 
ATOM 473  C CE1 . TYR A 1 61  ? -66.270  38.044  -32.393 1.00 50.91  ? 86  TYR A CE1 1 
ATOM 474  C CE2 . TYR A 1 61  ? -68.446  37.309  -31.724 1.00 50.20  ? 86  TYR A CE2 1 
ATOM 475  C CZ  . TYR A 1 61  ? -67.115  37.042  -31.966 1.00 53.15  ? 86  TYR A CZ  1 
ATOM 476  O OH  . TYR A 1 61  ? -66.626  35.769  -31.783 1.00 58.06  ? 86  TYR A OH  1 
ATOM 477  N N   . LYS A 1 62  ? -66.056  42.372  -31.367 1.00 58.21  ? 87  LYS A N   1 
ATOM 478  C CA  . LYS A 1 62  ? -64.696  42.281  -30.845 1.00 65.97  ? 87  LYS A CA  1 
ATOM 479  C C   . LYS A 1 62  ? -64.564  43.004  -29.510 1.00 71.04  ? 87  LYS A C   1 
ATOM 480  O O   . LYS A 1 62  ? -63.912  42.504  -28.583 1.00 66.14  ? 87  LYS A O   1 
ATOM 481  C CB  . LYS A 1 62  ? -63.706  42.853  -31.860 1.00 56.88  ? 87  LYS A CB  1 
ATOM 482  C CG  . LYS A 1 62  ? -63.283  41.873  -32.944 1.00 79.11  ? 87  LYS A CG  1 
ATOM 483  C CD  . LYS A 1 62  ? -62.495  42.562  -34.055 1.00 104.92 ? 87  LYS A CD  1 
ATOM 484  C CE  . LYS A 1 62  ? -61.728  43.777  -33.547 1.00 117.16 ? 87  LYS A CE  1 
ATOM 485  N NZ  . LYS A 1 62  ? -61.053  44.506  -34.659 1.00 120.18 ? 87  LYS A NZ  1 
ATOM 486  N N   . ASN A 1 63  ? -65.168  44.190  -29.400 1.00 59.92  ? 88  ASN A N   1 
ATOM 487  C CA  . ASN A 1 63  ? -65.137  44.927  -28.144 1.00 58.65  ? 88  ASN A CA  1 
ATOM 488  C C   . ASN A 1 63  ? -65.842  44.158  -27.039 1.00 75.54  ? 88  ASN A C   1 
ATOM 489  O O   . ASN A 1 63  ? -65.367  44.124  -25.900 1.00 71.06  ? 88  ASN A O   1 
ATOM 490  C CB  . ASN A 1 63  ? -65.767  46.306  -28.331 1.00 53.51  ? 88  ASN A CB  1 
ATOM 491  C CG  . ASN A 1 63  ? -64.878  47.245  -29.113 1.00 69.49  ? 88  ASN A CG  1 
ATOM 492  O OD1 . ASN A 1 63  ? -63.672  47.024  -29.225 1.00 70.06  ? 88  ASN A OD1 1 
ATOM 493  N ND2 . ASN A 1 63  ? -65.468  48.302  -29.661 1.00 86.36  ? 88  ASN A ND2 1 
ATOM 494  N N   . ALA A 1 64  ? -66.978  43.529  -27.356 1.00 68.75  ? 89  ALA A N   1 
ATOM 495  C CA  . ALA A 1 64  ? -67.678  42.734  -26.353 1.00 65.08  ? 89  ALA A CA  1 
ATOM 496  C C   . ALA A 1 64  ? -66.819  41.570  -25.876 1.00 68.50  ? 89  ALA A C   1 
ATOM 497  O O   . ALA A 1 64  ? -66.740  41.296  -24.670 1.00 62.76  ? 89  ALA A O   1 
ATOM 498  C CB  . ALA A 1 64  ? -69.006  42.229  -26.917 1.00 50.81  ? 89  ALA A CB  1 
ATOM 499  N N   . VAL A 1 65  ? -66.152  40.885  -26.807 1.00 61.34  ? 90  VAL A N   1 
ATOM 500  C CA  . VAL A 1 65  ? -65.331  39.737  -26.424 1.00 61.69  ? 90  VAL A CA  1 
ATOM 501  C C   . VAL A 1 65  ? -64.157  40.183  -25.556 1.00 63.56  ? 90  VAL A C   1 
ATOM 502  O O   . VAL A 1 65  ? -63.861  39.574  -24.518 1.00 62.92  ? 90  VAL A O   1 
ATOM 503  C CB  . VAL A 1 65  ? -64.856  38.972  -27.672 1.00 62.23  ? 90  VAL A CB  1 
ATOM 504  C CG1 . VAL A 1 65  ? -63.830  37.919  -27.284 1.00 45.89  ? 90  VAL A CG1 1 
ATOM 505  C CG2 . VAL A 1 65  ? -66.040  38.340  -28.388 1.00 58.72  ? 90  VAL A CG2 1 
ATOM 506  N N   . THR A 1 66  ? -63.475  41.261  -25.960 1.00 58.55  ? 91  THR A N   1 
ATOM 507  C CA  . THR A 1 66  ? -62.325  41.725  -25.186 1.00 58.13  ? 91  THR A CA  1 
ATOM 508  C C   . THR A 1 66  ? -62.751  42.256  -23.822 1.00 71.55  ? 91  THR A C   1 
ATOM 509  O O   . THR A 1 66  ? -62.037  42.075  -22.829 1.00 65.07  ? 91  THR A O   1 
ATOM 510  C CB  . THR A 1 66  ? -61.553  42.796  -25.955 1.00 41.33  ? 91  THR A CB  1 
ATOM 511  O OG1 . THR A 1 66  ? -62.437  43.866  -26.307 1.00 78.39  ? 91  THR A OG1 1 
ATOM 512  C CG2 . THR A 1 66  ? -60.946  42.208  -27.218 1.00 64.98  ? 91  THR A CG2 1 
ATOM 513  N N   . GLU A 1 67  ? -63.908  42.919  -23.753 1.00 69.59  ? 92  GLU A N   1 
ATOM 514  C CA  . GLU A 1 67  ? -64.417  43.396  -22.474 1.00 62.12  ? 92  GLU A CA  1 
ATOM 515  C C   . GLU A 1 67  ? -64.750  42.233  -21.548 1.00 60.91  ? 92  GLU A C   1 
ATOM 516  O O   . GLU A 1 67  ? -64.471  42.292  -20.345 1.00 72.21  ? 92  GLU A O   1 
ATOM 517  C CB  . GLU A 1 67  ? -65.638  44.284  -22.710 1.00 60.06  ? 92  GLU A CB  1 
ATOM 518  C CG  . GLU A 1 67  ? -66.396  44.686  -21.463 1.00 83.67  ? 92  GLU A CG  1 
ATOM 519  C CD  . GLU A 1 67  ? -67.605  45.544  -21.786 1.00 99.06  ? 92  GLU A CD  1 
ATOM 520  O OE1 . GLU A 1 67  ? -67.994  45.598  -22.972 1.00 113.45 ? 92  GLU A OE1 1 
ATOM 521  O OE2 . GLU A 1 67  ? -68.165  46.164  -20.857 1.00 112.92 ? 92  GLU A OE2 1 
ATOM 522  N N   . LEU A 1 68  ? -65.329  41.159  -22.092 1.00 66.57  ? 93  LEU A N   1 
ATOM 523  C CA  . LEU A 1 68  ? -65.579  39.974  -21.277 1.00 54.24  ? 93  LEU A CA  1 
ATOM 524  C C   . LEU A 1 68  ? -64.274  39.346  -20.801 1.00 61.23  ? 93  LEU A C   1 
ATOM 525  O O   . LEU A 1 68  ? -64.188  38.866  -19.668 1.00 62.68  ? 93  LEU A O   1 
ATOM 526  C CB  . LEU A 1 68  ? -66.413  38.958  -22.056 1.00 61.00  ? 93  LEU A CB  1 
ATOM 527  C CG  . LEU A 1 68  ? -67.883  39.333  -22.264 1.00 53.15  ? 93  LEU A CG  1 
ATOM 528  C CD1 . LEU A 1 68  ? -68.569  38.348  -23.203 1.00 58.47  ? 93  LEU A CD1 1 
ATOM 529  C CD2 . LEU A 1 68  ? -68.616  39.427  -20.934 1.00 52.77  ? 93  LEU A CD2 1 
ATOM 530  N N   . GLN A 1 69  ? -63.247  39.332  -21.654 1.00 61.90  ? 94  GLN A N   1 
ATOM 531  C CA  . GLN A 1 69  ? -61.948  38.810  -21.227 1.00 67.39  ? 94  GLN A CA  1 
ATOM 532  C C   . GLN A 1 69  ? -61.354  39.653  -20.100 1.00 64.00  ? 94  GLN A C   1 
ATOM 533  O O   . GLN A 1 69  ? -60.819  39.115  -19.117 1.00 85.56  ? 94  GLN A O   1 
ATOM 534  C CB  . GLN A 1 69  ? -60.995  38.749  -22.420 1.00 62.87  ? 94  GLN A CB  1 
ATOM 535  C CG  . GLN A 1 69  ? -61.353  37.672  -23.436 1.00 70.08  ? 94  GLN A CG  1 
ATOM 536  C CD  . GLN A 1 69  ? -60.521  37.752  -24.702 1.00 65.25  ? 94  GLN A CD  1 
ATOM 537  O OE1 . GLN A 1 69  ? -60.154  38.837  -25.150 1.00 69.67  ? 94  GLN A OE1 1 
ATOM 538  N NE2 . GLN A 1 69  ? -60.219  36.598  -25.285 1.00 63.89  ? 94  GLN A NE2 1 
ATOM 539  N N   . LEU A 1 70  ? -61.443  40.979  -20.225 1.00 70.88  ? 95  LEU A N   1 
ATOM 540  C CA  . LEU A 1 70  ? -60.952  41.866  -19.175 1.00 70.25  ? 95  LEU A CA  1 
ATOM 541  C C   . LEU A 1 70  ? -61.742  41.686  -17.886 1.00 71.52  ? 95  LEU A C   1 
ATOM 542  O O   . LEU A 1 70  ? -61.190  41.832  -16.790 1.00 85.60  ? 95  LEU A O   1 
ATOM 543  C CB  . LEU A 1 70  ? -61.008  43.320  -19.650 1.00 66.19  ? 95  LEU A CB  1 
ATOM 544  C CG  . LEU A 1 70  ? -60.831  44.431  -18.612 1.00 74.98  ? 95  LEU A CG  1 
ATOM 545  C CD1 . LEU A 1 70  ? -59.360  44.605  -18.266 1.00 81.99  ? 95  LEU A CD1 1 
ATOM 546  C CD2 . LEU A 1 70  ? -61.424  45.740  -19.110 1.00 57.98  ? 95  LEU A CD2 1 
ATOM 547  N N   . LEU A 1 71  ? -63.037  41.385  -17.995 1.00 70.86  ? 96  LEU A N   1 
ATOM 548  C CA  . LEU A 1 71  ? -63.804  40.995  -16.817 1.00 66.11  ? 96  LEU A CA  1 
ATOM 549  C C   . LEU A 1 71  ? -63.273  39.693  -16.230 1.00 75.73  ? 96  LEU A C   1 
ATOM 550  O O   . LEU A 1 71  ? -63.167  39.550  -15.007 1.00 94.40  ? 96  LEU A O   1 
ATOM 551  C CB  . LEU A 1 71  ? -65.280  40.853  -17.182 1.00 57.76  ? 96  LEU A CB  1 
ATOM 552  C CG  . LEU A 1 71  ? -66.274  40.721  -16.029 1.00 65.51  ? 96  LEU A CG  1 
ATOM 553  C CD1 . LEU A 1 71  ? -65.913  41.669  -14.892 1.00 68.64  ? 96  LEU A CD1 1 
ATOM 554  C CD2 . LEU A 1 71  ? -67.694  40.965  -16.520 1.00 69.12  ? 96  LEU A CD2 1 
ATOM 555  N N   . MET A 1 72  ? -62.931  38.734  -17.095 1.00 86.95  ? 97  MET A N   1 
ATOM 556  C CA  . MET A 1 72  ? -62.432  37.438  -16.644 1.00 85.72  ? 97  MET A CA  1 
ATOM 557  C C   . MET A 1 72  ? -61.099  37.547  -15.922 1.00 92.16  ? 97  MET A C   1 
ATOM 558  O O   . MET A 1 72  ? -60.781  36.685  -15.094 1.00 94.33  ? 97  MET A O   1 
ATOM 559  C CB  . MET A 1 72  ? -62.299  36.476  -17.822 1.00 94.81  ? 97  MET A CB  1 
ATOM 560  C CG  . MET A 1 72  ? -62.960  35.143  -17.571 1.00 98.41  ? 97  MET A CG  1 
ATOM 561  S SD  . MET A 1 72  ? -64.699  35.395  -17.212 1.00 101.53 ? 97  MET A SD  1 
ATOM 562  C CE  . MET A 1 72  ? -65.232  35.965  -18.820 1.00 93.10  ? 97  MET A CE  1 
ATOM 563  N N   . GLN A 1 73  ? -60.300  38.575  -16.216 1.00 90.82  ? 98  GLN A N   1 
ATOM 564  C CA  . GLN A 1 73  ? -59.085  38.702  -15.413 1.00 98.83  ? 98  GLN A CA  1 
ATOM 565  C C   . GLN A 1 73  ? -59.381  39.078  -13.960 1.00 114.83 ? 98  GLN A C   1 
ATOM 566  O O   . GLN A 1 73  ? -58.439  39.229  -13.171 1.00 119.24 ? 98  GLN A O   1 
ATOM 567  C CB  . GLN A 1 73  ? -58.115  39.716  -16.031 1.00 93.71  ? 98  GLN A CB  1 
ATOM 568  C CG  . GLN A 1 73  ? -58.396  41.172  -15.701 1.00 110.17 ? 98  GLN A CG  1 
ATOM 569  C CD  . GLN A 1 73  ? -57.274  42.095  -16.148 1.00 108.73 ? 98  GLN A CD  1 
ATOM 570  O OE1 . GLN A 1 73  ? -56.607  41.841  -17.152 1.00 114.33 ? 98  GLN A OE1 1 
ATOM 571  N NE2 . GLN A 1 73  ? -57.061  43.175  -15.400 1.00 88.35  ? 98  GLN A NE2 1 
ATOM 572  N N   . SER A 1 74  ? -60.656  39.228  -13.594 1.00 118.05 ? 99  SER A N   1 
ATOM 573  C CA  . SER A 1 74  ? -61.099  39.409  -12.214 1.00 123.95 ? 99  SER A CA  1 
ATOM 574  C C   . SER A 1 74  ? -62.060  38.272  -11.879 1.00 124.48 ? 99  SER A C   1 
ATOM 575  O O   . SER A 1 74  ? -63.171  38.216  -12.417 1.00 110.77 ? 99  SER A O   1 
ATOM 576  C CB  . SER A 1 74  ? -61.772  40.769  -12.028 1.00 112.55 ? 99  SER A CB  1 
ATOM 577  O OG  . SER A 1 74  ? -60.999  41.812  -12.596 1.00 102.08 ? 99  SER A OG  1 
ATOM 578  N N   . THR A 1 75  ? -61.639  37.379  -10.985 1.00 140.95 ? 100 THR A N   1 
ATOM 579  C CA  . THR A 1 75  ? -62.423  36.191  -10.676 1.00 136.59 ? 100 THR A CA  1 
ATOM 580  C C   . THR A 1 75  ? -63.748  36.567  -10.009 1.00 144.53 ? 100 THR A C   1 
ATOM 581  O O   . THR A 1 75  ? -63.823  37.552  -9.268  1.00 141.87 ? 100 THR A O   1 
ATOM 582  C CB  . THR A 1 75  ? -61.631  35.251  -9.768  1.00 130.65 ? 100 THR A CB  1 
ATOM 583  O OG1 . THR A 1 75  ? -61.082  35.991  -8.670  1.00 120.43 ? 100 THR A OG1 1 
ATOM 584  C CG2 . THR A 1 75  ? -60.502  34.587  -10.545 1.00 116.44 ? 100 THR A CG2 1 
ATOM 585  N N   . PRO A 1 76  ? -64.810  35.796  -10.258 1.00 146.27 ? 101 PRO A N   1 
ATOM 586  C CA  . PRO A 1 76  ? -66.129  36.171  -9.730  1.00 142.03 ? 101 PRO A CA  1 
ATOM 587  C C   . PRO A 1 76  ? -66.202  36.048  -8.216  1.00 140.16 ? 101 PRO A C   1 
ATOM 588  O O   . PRO A 1 76  ? -65.678  35.102  -7.622  1.00 140.97 ? 101 PRO A O   1 
ATOM 589  C CB  . PRO A 1 76  ? -67.078  35.179  -10.415 1.00 127.16 ? 101 PRO A CB  1 
ATOM 590  C CG  . PRO A 1 76  ? -66.226  33.995  -10.716 1.00 114.96 ? 101 PRO A CG  1 
ATOM 591  C CD  . PRO A 1 76  ? -64.860  34.542  -11.031 1.00 135.35 ? 101 PRO A CD  1 
ATOM 592  N N   . ALA A 1 77  ? -66.875  37.020  -7.598  1.00 148.36 ? 102 ALA A N   1 
ATOM 593  C CA  . ALA A 1 77  ? -67.111  37.036  -6.159  1.00 151.82 ? 102 ALA A CA  1 
ATOM 594  C C   . ALA A 1 77  ? -68.163  38.082  -5.814  1.00 145.12 ? 102 ALA A C   1 
ATOM 595  O O   . ALA A 1 77  ? -68.069  39.231  -6.258  1.00 147.95 ? 102 ALA A O   1 
ATOM 596  C CB  . ALA A 1 77  ? -65.815  37.314  -5.393  1.00 137.26 ? 102 ALA A CB  1 
ATOM 597  N N   . THR A 1 78  ? -69.167  37.703  -5.027  1.00 137.12 ? 103 THR A N   1 
ATOM 598  C CA  . THR A 1 78  ? -70.227  38.616  -4.622  1.00 144.31 ? 103 THR A CA  1 
ATOM 599  C C   . THR A 1 78  ? -70.031  39.019  -3.164  1.00 152.49 ? 103 THR A C   1 
ATOM 600  O O   . THR A 1 78  ? -69.673  38.189  -2.320  1.00 153.20 ? 103 THR A O   1 
ATOM 601  C CB  . THR A 1 78  ? -71.615  37.988  -4.833  1.00 129.77 ? 103 THR A CB  1 
ATOM 602  O OG1 . THR A 1 78  ? -72.633  38.957  -4.551  1.00 127.81 ? 103 THR A OG1 1 
ATOM 603  C CG2 . THR A 1 78  ? -71.819  36.763  -3.944  1.00 134.22 ? 103 THR A CG2 1 
ATOM 604  N N   . ASN A 1 79  ? -70.233  40.303  -2.882  1.00 143.66 ? 104 ASN A N   1 
ATOM 605  C CA  . ASN A 1 79  ? -70.088  40.832  -1.527  1.00 135.76 ? 104 ASN A CA  1 
ATOM 606  C C   . ASN A 1 79  ? -70.746  42.204  -1.409  1.00 119.62 ? 104 ASN A C   1 
ATOM 607  O O   . ASN A 1 79  ? -70.697  43.010  -2.339  1.00 115.23 ? 104 ASN A O   1 
ATOM 608  C CB  . ASN A 1 79  ? -68.608  40.917  -1.133  1.00 119.51 ? 104 ASN A CB  1 
ATOM 609  C CG  . ASN A 1 79  ? -68.397  40.873  0.375   1.00 118.79 ? 104 ASN A CG  1 
ATOM 610  O OD1 . ASN A 1 79  ? -68.134  39.815  0.946   1.00 105.22 ? 104 ASN A OD1 1 
ATOM 611  N ND2 . ASN A 1 79  ? -68.498  42.029  1.022   1.00 106.70 ? 104 ASN A ND2 1 
ATOM 612  N N   . GLU B 2 1   ? -59.448  7.905   -31.950 1.00 75.79  ? 2   GLU L N   1 
ATOM 613  C CA  . GLU B 2 1   ? -59.798  8.508   -33.233 1.00 86.79  ? 2   GLU L CA  1 
ATOM 614  C C   . GLU B 2 1   ? -59.803  7.473   -34.359 1.00 79.49  ? 2   GLU L C   1 
ATOM 615  O O   . GLU B 2 1   ? -60.591  7.573   -35.297 1.00 90.37  ? 2   GLU L O   1 
ATOM 616  C CB  . GLU B 2 1   ? -58.830  9.645   -33.568 1.00 84.08  ? 2   GLU L CB  1 
ATOM 617  C CG  . GLU B 2 1   ? -59.110  10.325  -34.896 1.00 81.07  ? 2   GLU L CG  1 
ATOM 618  C CD  . GLU B 2 1   ? -57.856  10.854  -35.556 1.00 95.39  ? 2   GLU L CD  1 
ATOM 619  O OE1 . GLU B 2 1   ? -56.761  10.676  -34.982 1.00 108.34 ? 2   GLU L OE1 1 
ATOM 620  O OE2 . GLU B 2 1   ? -57.968  11.451  -36.649 1.00 98.78  ? 2   GLU L OE2 1 
ATOM 621  N N   . ILE B 2 2   ? -58.923  6.479   -34.261 1.00 86.44  ? 3   ILE L N   1 
ATOM 622  C CA  . ILE B 2 2   ? -58.838  5.432   -35.278 1.00 91.98  ? 3   ILE L CA  1 
ATOM 623  C C   . ILE B 2 2   ? -59.850  4.320   -35.025 1.00 94.84  ? 3   ILE L C   1 
ATOM 624  O O   . ILE B 2 2   ? -60.506  3.858   -35.962 1.00 97.52  ? 3   ILE L O   1 
ATOM 625  C CB  . ILE B 2 2   ? -57.397  4.887   -35.348 1.00 99.20  ? 3   ILE L CB  1 
ATOM 626  C CG1 . ILE B 2 2   ? -56.470  5.920   -35.991 1.00 101.81 ? 3   ILE L CG1 1 
ATOM 627  C CG2 . ILE B 2 2   ? -57.344  3.580   -36.128 1.00 98.02  ? 3   ILE L CG2 1 
ATOM 628  C CD1 . ILE B 2 2   ? -56.924  6.370   -37.362 1.00 102.86 ? 3   ILE L CD1 1 
ATOM 629  N N   . VAL B 2 3   ? -59.998  3.914   -33.757 1.00 86.51  ? 4   VAL L N   1 
ATOM 630  C CA  . VAL B 2 3   ? -60.886  2.852   -33.265 1.00 88.90  ? 4   VAL L CA  1 
ATOM 631  C C   . VAL B 2 3   ? -61.029  1.689   -34.248 1.00 80.19  ? 4   VAL L C   1 
ATOM 632  O O   . VAL B 2 3   ? -61.851  1.726   -35.171 1.00 67.23  ? 4   VAL L O   1 
ATOM 633  C CB  . VAL B 2 3   ? -62.273  3.409   -32.854 1.00 76.98  ? 4   VAL L CB  1 
ATOM 634  C CG1 . VAL B 2 3   ? -62.188  4.122   -31.502 1.00 46.47  ? 4   VAL L CG1 1 
ATOM 635  C CG2 . VAL B 2 3   ? -62.868  4.344   -33.900 1.00 77.45  ? 4   VAL L CG2 1 
ATOM 636  N N   . THR B 2 4   ? -60.239  0.636   -34.036 1.00 86.33  ? 5   THR L N   1 
ATOM 637  C CA  . THR B 2 4   ? -60.304  -0.591  -34.819 1.00 82.90  ? 5   THR L CA  1 
ATOM 638  C C   . THR B 2 4   ? -60.899  -1.717  -33.980 1.00 84.62  ? 5   THR L C   1 
ATOM 639  O O   . THR B 2 4   ? -60.618  -1.831  -32.782 1.00 78.37  ? 5   THR L O   1 
ATOM 640  C CB  . THR B 2 4   ? -58.916  -1.002  -35.325 1.00 79.68  ? 5   THR L CB  1 
ATOM 641  O OG1 . THR B 2 4   ? -57.990  -1.025  -34.231 1.00 80.05  ? 5   THR L OG1 1 
ATOM 642  C CG2 . THR B 2 4   ? -58.421  -0.025  -36.380 1.00 96.83  ? 5   THR L CG2 1 
ATOM 643  N N   . GLN B 2 5   ? -61.718  -2.550  -34.615 1.00 74.87  ? 6   GLN L N   1 
ATOM 644  C CA  . GLN B 2 5   ? -62.419  -3.634  -33.942 1.00 73.15  ? 6   GLN L CA  1 
ATOM 645  C C   . GLN B 2 5   ? -61.717  -4.968  -34.168 1.00 88.98  ? 6   GLN L C   1 
ATOM 646  O O   . GLN B 2 5   ? -60.938  -5.142  -35.109 1.00 89.28  ? 6   GLN L O   1 
ATOM 647  C CB  . GLN B 2 5   ? -63.870  -3.725  -34.422 1.00 77.88  ? 6   GLN L CB  1 
ATOM 648  C CG  . GLN B 2 5   ? -64.698  -2.490  -34.127 1.00 68.06  ? 6   GLN L CG  1 
ATOM 649  C CD  . GLN B 2 5   ? -66.179  -2.717  -34.351 1.00 73.41  ? 6   GLN L CD  1 
ATOM 650  O OE1 . GLN B 2 5   ? -66.874  -1.859  -34.894 1.00 78.28  ? 6   GLN L OE1 1 
ATOM 651  N NE2 . GLN B 2 5   ? -66.670  -3.880  -33.936 1.00 67.48  ? 6   GLN L NE2 1 
ATOM 652  N N   . SER B 2 6   ? -62.012  -5.920  -33.279 1.00 101.15 ? 7   SER L N   1 
ATOM 653  C CA  . SER B 2 6   ? -61.401  -7.239  -33.300 1.00 84.08  ? 7   SER L CA  1 
ATOM 654  C C   . SER B 2 6   ? -62.375  -8.273  -32.754 1.00 92.48  ? 7   SER L C   1 
ATOM 655  O O   . SER B 2 6   ? -63.087  -7.995  -31.774 1.00 87.43  ? 7   SER L O   1 
ATOM 656  C CB  . SER B 2 6   ? -60.107  -7.274  -32.480 1.00 75.16  ? 7   SER L CB  1 
ATOM 657  O OG  . SER B 2 6   ? -59.203  -6.268  -32.902 1.00 102.60 ? 7   SER L OG  1 
ATOM 658  N N   . PRO B 2 7   ? -62.446  -9.457  -33.369 1.00 97.16  ? 8   PRO L N   1 
ATOM 659  C CA  . PRO B 2 7   ? -61.801  -9.833  -34.631 1.00 74.50  ? 8   PRO L CA  1 
ATOM 660  C C   . PRO B 2 7   ? -62.687  -9.439  -35.803 1.00 82.61  ? 8   PRO L C   1 
ATOM 661  O O   . PRO B 2 7   ? -63.767  -8.893  -35.593 1.00 78.11  ? 8   PRO L O   1 
ATOM 662  C CB  . PRO B 2 7   ? -61.644  -11.350 -34.497 1.00 73.70  ? 8   PRO L CB  1 
ATOM 663  C CG  . PRO B 2 7   ? -62.823  -11.760 -33.669 1.00 90.70  ? 8   PRO L CG  1 
ATOM 664  C CD  . PRO B 2 7   ? -63.084  -10.615 -32.716 1.00 93.92  ? 8   PRO L CD  1 
ATOM 665  N N   . GLY B 2 8   ? -62.259  -9.689  -37.042 1.00 78.90  ? 9   GLY L N   1 
ATOM 666  C CA  . GLY B 2 8   ? -63.104  -9.362  -38.179 1.00 68.05  ? 9   GLY L CA  1 
ATOM 667  C C   . GLY B 2 8   ? -64.393  -10.160 -38.189 1.00 66.36  ? 9   GLY L C   1 
ATOM 668  O O   . GLY B 2 8   ? -65.480  -9.610  -38.381 1.00 54.50  ? 9   GLY L O   1 
ATOM 669  N N   . THR B 2 9   ? -64.289  -11.469 -37.970 1.00 80.51  ? 10  THR L N   1 
ATOM 670  C CA  . THR B 2 9   ? -65.447  -12.349 -37.909 1.00 78.21  ? 10  THR L CA  1 
ATOM 671  C C   . THR B 2 9   ? -65.341  -13.236 -36.679 1.00 75.54  ? 10  THR L C   1 
ATOM 672  O O   . THR B 2 9   ? -64.267  -13.765 -36.373 1.00 74.92  ? 10  THR L O   1 
ATOM 673  C CB  . THR B 2 9   ? -65.569  -13.215 -39.167 1.00 66.86  ? 10  THR L CB  1 
ATOM 674  O OG1 . THR B 2 9   ? -65.609  -12.373 -40.326 1.00 90.84  ? 10  THR L OG1 1 
ATOM 675  C CG2 . THR B 2 9   ? -66.840  -14.055 -39.116 1.00 65.44  ? 10  THR L CG2 1 
ATOM 676  N N   . LEU B 2 10  ? -66.457  -13.390 -35.975 1.00 76.79  ? 11  LEU L N   1 
ATOM 677  C CA  . LEU B 2 10  ? -66.526  -14.204 -34.770 1.00 71.26  ? 11  LEU L CA  1 
ATOM 678  C C   . LEU B 2 10  ? -67.420  -15.406 -35.051 1.00 64.53  ? 11  LEU L C   1 
ATOM 679  O O   . LEU B 2 10  ? -68.580  -15.242 -35.449 1.00 48.02  ? 11  LEU L O   1 
ATOM 680  C CB  . LEU B 2 10  ? -67.060  -13.385 -33.595 1.00 73.10  ? 11  LEU L CB  1 
ATOM 681  C CG  . LEU B 2 10  ? -66.653  -13.835 -32.195 1.00 65.68  ? 11  LEU L CG  1 
ATOM 682  C CD1 . LEU B 2 10  ? -65.143  -13.923 -32.096 1.00 55.65  ? 11  LEU L CD1 1 
ATOM 683  C CD2 . LEU B 2 10  ? -67.205  -12.880 -31.150 1.00 79.79  ? 11  LEU L CD2 1 
ATOM 684  N N   . SER B 2 11  ? -66.880  -16.606 -34.851 1.00 56.77  ? 12  SER L N   1 
ATOM 685  C CA  . SER B 2 11  ? -67.603  -17.853 -35.085 1.00 69.62  ? 12  SER L CA  1 
ATOM 686  C C   . SER B 2 11  ? -67.904  -18.494 -33.735 1.00 74.36  ? 12  SER L C   1 
ATOM 687  O O   . SER B 2 11  ? -66.988  -18.943 -33.037 1.00 66.62  ? 12  SER L O   1 
ATOM 688  C CB  . SER B 2 11  ? -66.793  -18.795 -35.974 1.00 66.05  ? 12  SER L CB  1 
ATOM 689  O OG  . SER B 2 11  ? -66.505  -18.194 -37.225 1.00 77.55  ? 12  SER L OG  1 
ATOM 690  N N   . LEU B 2 12  ? -69.185  -18.533 -33.371 1.00 67.20  ? 13  LEU L N   1 
ATOM 691  C CA  . LEU B 2 12  ? -69.606  -19.069 -32.085 1.00 57.81  ? 13  LEU L CA  1 
ATOM 692  C C   . LEU B 2 12  ? -70.951  -19.765 -32.238 1.00 62.89  ? 13  LEU L C   1 
ATOM 693  O O   . LEU B 2 12  ? -71.812  -19.310 -32.997 1.00 56.11  ? 13  LEU L O   1 
ATOM 694  C CB  . LEU B 2 12  ? -69.704  -17.966 -31.024 1.00 60.06  ? 13  LEU L CB  1 
ATOM 695  C CG  . LEU B 2 12  ? -68.396  -17.305 -30.584 1.00 67.76  ? 13  LEU L CG  1 
ATOM 696  C CD1 . LEU B 2 12  ? -68.682  -16.059 -29.781 1.00 67.57  ? 13  LEU L CD1 1 
ATOM 697  C CD2 . LEU B 2 12  ? -67.546  -18.277 -29.778 1.00 63.23  ? 13  LEU L CD2 1 
ATOM 698  N N   . SER B 2 13  ? -71.124  -20.862 -31.504 1.00 65.63  ? 14  SER L N   1 
ATOM 699  C CA  . SER B 2 13  ? -72.387  -21.578 -31.496 1.00 60.05  ? 14  SER L CA  1 
ATOM 700  C C   . SER B 2 13  ? -73.452  -20.757 -30.773 1.00 63.62  ? 14  SER L C   1 
ATOM 701  O O   . SER B 2 13  ? -73.133  -19.897 -29.949 1.00 60.01  ? 14  SER L O   1 
ATOM 702  C CB  . SER B 2 13  ? -72.223  -22.936 -30.817 1.00 71.32  ? 14  SER L CB  1 
ATOM 703  O OG  . SER B 2 13  ? -71.041  -23.589 -31.248 1.00 85.41  ? 14  SER L OG  1 
ATOM 704  N N   . PRO B 2 14  ? -74.728  -20.993 -31.078 1.00 53.80  ? 15  PRO L N   1 
ATOM 705  C CA  . PRO B 2 14  ? -75.795  -20.299 -30.346 1.00 55.07  ? 15  PRO L CA  1 
ATOM 706  C C   . PRO B 2 14  ? -75.750  -20.632 -28.861 1.00 56.28  ? 15  PRO L C   1 
ATOM 707  O O   . PRO B 2 14  ? -75.460  -21.762 -28.465 1.00 62.83  ? 15  PRO L O   1 
ATOM 708  C CB  . PRO B 2 14  ? -77.079  -20.823 -31.002 1.00 51.94  ? 15  PRO L CB  1 
ATOM 709  C CG  . PRO B 2 14  ? -76.651  -21.321 -32.339 1.00 46.43  ? 15  PRO L CG  1 
ATOM 710  C CD  . PRO B 2 14  ? -75.260  -21.845 -32.155 1.00 45.19  ? 15  PRO L CD  1 
ATOM 711  N N   . GLY B 2 15  ? -76.041  -19.627 -28.039 1.00 68.43  ? 16  GLY L N   1 
ATOM 712  C CA  . GLY B 2 15  ? -76.024  -19.782 -26.601 1.00 56.12  ? 16  GLY L CA  1 
ATOM 713  C C   . GLY B 2 15  ? -74.668  -19.633 -25.949 1.00 53.30  ? 16  GLY L C   1 
ATOM 714  O O   . GLY B 2 15  ? -74.587  -19.683 -24.715 1.00 69.55  ? 16  GLY L O   1 
ATOM 715  N N   . GLU B 2 16  ? -73.605  -19.451 -26.726 1.00 44.56  ? 17  GLU L N   1 
ATOM 716  C CA  . GLU B 2 16  ? -72.278  -19.220 -26.181 1.00 52.74  ? 17  GLU L CA  1 
ATOM 717  C C   . GLU B 2 16  ? -72.075  -17.736 -25.887 1.00 58.41  ? 17  GLU L C   1 
ATOM 718  O O   . GLU B 2 16  ? -72.878  -16.881 -26.268 1.00 57.08  ? 17  GLU L O   1 
ATOM 719  C CB  . GLU B 2 16  ? -71.206  -19.727 -27.145 1.00 54.28  ? 17  GLU L CB  1 
ATOM 720  C CG  . GLU B 2 16  ? -71.255  -21.226 -27.392 1.00 64.21  ? 17  GLU L CG  1 
ATOM 721  C CD  . GLU B 2 16  ? -70.120  -21.711 -28.276 1.00 76.74  ? 17  GLU L CD  1 
ATOM 722  O OE1 . GLU B 2 16  ? -69.445  -20.866 -28.900 1.00 76.04  ? 17  GLU L OE1 1 
ATOM 723  O OE2 . GLU B 2 16  ? -69.905  -22.940 -28.347 1.00 89.16  ? 17  GLU L OE2 1 
ATOM 724  N N   . ARG B 2 17  ? -70.979  -17.433 -25.198 1.00 63.19  ? 18  ARG L N   1 
ATOM 725  C CA  . ARG B 2 17  ? -70.660  -16.064 -24.818 1.00 55.07  ? 18  ARG L CA  1 
ATOM 726  C C   . ARG B 2 17  ? -69.758  -15.437 -25.875 1.00 62.24  ? 18  ARG L C   1 
ATOM 727  O O   . ARG B 2 17  ? -68.751  -16.030 -26.274 1.00 70.72  ? 18  ARG L O   1 
ATOM 728  C CB  . ARG B 2 17  ? -69.988  -16.030 -23.442 1.00 49.56  ? 18  ARG L CB  1 
ATOM 729  C CG  . ARG B 2 17  ? -68.957  -14.925 -23.260 1.00 55.82  ? 18  ARG L CG  1 
ATOM 730  C CD  . ARG B 2 17  ? -68.239  -15.060 -21.928 1.00 59.93  ? 18  ARG L CD  1 
ATOM 731  N NE  . ARG B 2 17  ? -68.963  -14.399 -20.848 1.00 70.67  ? 18  ARG L NE  1 
ATOM 732  C CZ  . ARG B 2 17  ? -68.623  -13.230 -20.322 1.00 71.54  ? 18  ARG L CZ  1 
ATOM 733  N NH1 . ARG B 2 17  ? -67.553  -12.571 -20.735 1.00 78.74  ? 18  ARG L NH1 1 
ATOM 734  N NH2 . ARG B 2 17  ? -69.376  -12.709 -19.357 1.00 62.83  ? 18  ARG L NH2 1 
ATOM 735  N N   . ALA B 2 18  ? -70.126  -14.241 -26.327 1.00 60.57  ? 19  ALA L N   1 
ATOM 736  C CA  . ALA B 2 18  ? -69.393  -13.527 -27.364 1.00 65.39  ? 19  ALA L CA  1 
ATOM 737  C C   . ALA B 2 18  ? -68.675  -12.333 -26.753 1.00 58.07  ? 19  ALA L C   1 
ATOM 738  O O   . ALA B 2 18  ? -69.261  -11.596 -25.953 1.00 58.41  ? 19  ALA L O   1 
ATOM 739  C CB  . ALA B 2 18  ? -70.331  -13.066 -28.483 1.00 61.13  ? 19  ALA L CB  1 
ATOM 740  N N   . THR B 2 19  ? -67.413  -12.146 -27.136 1.00 57.26  ? 20  THR L N   1 
ATOM 741  C CA  . THR B 2 19  ? -66.593  -11.036 -26.666 1.00 53.74  ? 20  THR L CA  1 
ATOM 742  C C   . THR B 2 19  ? -66.017  -10.305 -27.871 1.00 60.38  ? 20  THR L C   1 
ATOM 743  O O   . THR B 2 19  ? -65.227  -10.880 -28.628 1.00 66.51  ? 20  THR L O   1 
ATOM 744  C CB  . THR B 2 19  ? -65.472  -11.532 -25.746 1.00 60.14  ? 20  THR L CB  1 
ATOM 745  O OG1 . THR B 2 19  ? -66.028  -11.943 -24.490 1.00 75.13  ? 20  THR L OG1 1 
ATOM 746  C CG2 . THR B 2 19  ? -64.436  -10.444 -25.515 1.00 51.21  ? 20  THR L CG2 1 
ATOM 747  N N   . LEU B 2 20  ? -66.406  -9.044  -28.044 1.00 60.90  ? 21  LEU L N   1 
ATOM 748  C CA  . LEU B 2 20  ? -65.960  -8.211  -29.153 1.00 61.73  ? 21  LEU L CA  1 
ATOM 749  C C   . LEU B 2 20  ? -65.110  -7.074  -28.604 1.00 62.50  ? 21  LEU L C   1 
ATOM 750  O O   . LEU B 2 20  ? -65.499  -6.427  -27.627 1.00 66.80  ? 21  LEU L O   1 
ATOM 751  C CB  . LEU B 2 20  ? -67.155  -7.650  -29.931 1.00 53.14  ? 21  LEU L CB  1 
ATOM 752  C CG  . LEU B 2 20  ? -68.130  -8.624  -30.602 1.00 65.00  ? 21  LEU L CG  1 
ATOM 753  C CD1 . LEU B 2 20  ? -69.162  -9.154  -29.620 1.00 46.82  ? 21  LEU L CD1 1 
ATOM 754  C CD2 . LEU B 2 20  ? -68.823  -7.961  -31.784 1.00 76.93  ? 21  LEU L CD2 1 
ATOM 755  N N   . SER B 2 21  ? -63.957  -6.827  -29.224 1.00 63.96  ? 22  SER L N   1 
ATOM 756  C CA  . SER B 2 21  ? -63.030  -5.811  -28.755 1.00 67.96  ? 22  SER L CA  1 
ATOM 757  C C   . SER B 2 21  ? -63.035  -4.614  -29.698 1.00 67.68  ? 22  SER L C   1 
ATOM 758  O O   . SER B 2 21  ? -63.195  -4.761  -30.911 1.00 76.52  ? 22  SER L O   1 
ATOM 759  C CB  . SER B 2 21  ? -61.611  -6.379  -28.640 1.00 68.18  ? 22  SER L CB  1 
ATOM 760  O OG  . SER B 2 21  ? -60.650  -5.346  -28.506 1.00 88.55  ? 22  SER L OG  1 
ATOM 761  N N   . CYS B 2 22  ? -62.861  -3.424  -29.122 1.00 66.79  ? 23  CYS L N   1 
ATOM 762  C CA  . CYS B 2 22  ? -62.739  -2.181  -29.880 1.00 58.96  ? 23  CYS L CA  1 
ATOM 763  C C   . CYS B 2 22  ? -61.625  -1.370  -29.232 1.00 70.62  ? 23  CYS L C   1 
ATOM 764  O O   . CYS B 2 22  ? -61.755  -0.941  -28.080 1.00 71.20  ? 23  CYS L O   1 
ATOM 765  C CB  . CYS B 2 22  ? -64.063  -1.407  -29.898 1.00 56.71  ? 23  CYS L CB  1 
ATOM 766  S SG  . CYS B 2 22  ? -64.003  0.294   -30.546 1.00 91.19  ? 23  CYS L SG  1 
ATOM 767  N N   . ARG B 2 23  ? -60.522  -1.186  -29.950 1.00 87.95  ? 24  ARG L N   1 
ATOM 768  C CA  . ARG B 2 23  ? -59.372  -0.453  -29.445 1.00 86.16  ? 24  ARG L CA  1 
ATOM 769  C C   . ARG B 2 23  ? -59.284  0.896   -30.145 1.00 81.30  ? 24  ARG L C   1 
ATOM 770  O O   . ARG B 2 23  ? -59.833  1.090   -31.231 1.00 80.52  ? 24  ARG L O   1 
ATOM 771  C CB  . ARG B 2 23  ? -58.080  -1.251  -29.656 1.00 88.08  ? 24  ARG L CB  1 
ATOM 772  C CG  . ARG B 2 23  ? -58.210  -2.728  -29.304 1.00 99.69  ? 24  ARG L CG  1 
ATOM 773  C CD  . ARG B 2 23  ? -56.991  -3.269  -28.570 1.00 103.92 ? 24  ARG L CD  1 
ATOM 774  N NE  . ARG B 2 23  ? -56.765  -2.612  -27.288 1.00 98.84  ? 24  ARG L NE  1 
ATOM 775  C CZ  . ARG B 2 23  ? -55.605  -2.099  -26.902 1.00 110.51 ? 24  ARG L CZ  1 
ATOM 776  N NH1 . ARG B 2 23  ? -54.542  -2.123  -27.689 1.00 117.17 ? 24  ARG L NH1 1 
ATOM 777  N NH2 . ARG B 2 23  ? -55.507  -1.555  -25.692 1.00 105.93 ? 24  ARG L NH2 1 
ATOM 778  N N   . ALA B 2 24  ? -58.589  1.836   -29.511 1.00 76.74  ? 25  ALA L N   1 
ATOM 779  C CA  . ALA B 2 24  ? -58.493  3.195   -30.023 1.00 83.27  ? 25  ALA L CA  1 
ATOM 780  C C   . ALA B 2 24  ? -57.035  3.614   -30.137 1.00 93.32  ? 25  ALA L C   1 
ATOM 781  O O   . ALA B 2 24  ? -56.176  3.152   -29.380 1.00 86.35  ? 25  ALA L O   1 
ATOM 782  C CB  . ALA B 2 24  ? -59.251  4.183   -29.128 1.00 73.39  ? 25  ALA L CB  1 
ATOM 783  N N   . SER B 2 25  ? -56.763  4.497   -31.102 1.00 92.92  ? 26  SER L N   1 
ATOM 784  C CA  . SER B 2 25  ? -55.410  5.018   -31.267 1.00 81.28  ? 26  SER L CA  1 
ATOM 785  C C   . SER B 2 25  ? -54.973  5.811   -30.043 1.00 79.24  ? 26  SER L C   1 
ATOM 786  O O   . SER B 2 25  ? -53.820  5.713   -29.608 1.00 89.06  ? 26  SER L O   1 
ATOM 787  C CB  . SER B 2 25  ? -55.327  5.883   -32.525 1.00 78.69  ? 26  SER L CB  1 
ATOM 788  O OG  . SER B 2 25  ? -56.485  6.686   -32.669 1.00 86.41  ? 26  SER L OG  1 
ATOM 789  N N   . GLN B 2 26  ? -55.878  6.605   -29.477 1.00 83.99  ? 27  GLN L N   1 
ATOM 790  C CA  . GLN B 2 26  ? -55.611  7.382   -28.277 1.00 84.31  ? 27  GLN L CA  1 
ATOM 791  C C   . GLN B 2 26  ? -56.767  7.203   -27.304 1.00 76.65  ? 27  GLN L C   1 
ATOM 792  O O   . GLN B 2 26  ? -57.809  6.634   -27.641 1.00 78.04  ? 27  GLN L O   1 
ATOM 793  C CB  . GLN B 2 26  ? -55.402  8.866   -28.609 1.00 87.88  ? 27  GLN L CB  1 
ATOM 794  C CG  . GLN B 2 26  ? -56.551  9.498   -29.375 1.00 94.50  ? 27  GLN L CG  1 
ATOM 795  C CD  . GLN B 2 26  ? -56.231  10.903  -29.841 1.00 106.37 ? 27  GLN L CD  1 
ATOM 796  O OE1 . GLN B 2 26  ? -56.701  11.884  -29.264 1.00 110.01 ? 27  GLN L OE1 1 
ATOM 797  N NE2 . GLN B 2 26  ? -55.427  11.008  -30.895 1.00 107.50 ? 27  GLN L NE2 1 
ATOM 798  N N   . ASN B 2 27  ? -56.572  7.690   -26.080 1.00 72.80  ? 28  ASN L N   1 
ATOM 799  C CA  . ASN B 2 27  ? -57.605  7.574   -25.059 1.00 81.31  ? 28  ASN L CA  1 
ATOM 800  C C   . ASN B 2 27  ? -58.870  8.306   -25.488 1.00 75.12  ? 28  ASN L C   1 
ATOM 801  O O   . ASN B 2 27  ? -58.817  9.449   -25.953 1.00 70.04  ? 28  ASN L O   1 
ATOM 802  C CB  . ASN B 2 27  ? -57.098  8.125   -23.726 1.00 78.83  ? 28  ASN L CB  1 
ATOM 803  C CG  . ASN B 2 27  ? -56.129  7.186   -23.040 1.00 92.65  ? 28  ASN L CG  1 
ATOM 804  O OD1 . ASN B 2 27  ? -56.268  5.965   -23.122 1.00 93.51  ? 28  ASN L OD1 1 
ATOM 805  N ND2 . ASN B 2 27  ? -55.137  7.750   -22.359 1.00 96.68  ? 28  ASN L ND2 1 
ATOM 806  N N   . VAL B 2 28  ? -60.010  7.639   -25.333 1.00 74.18  ? 29  VAL L N   1 
ATOM 807  C CA  . VAL B 2 28  ? -61.298  8.234   -25.670 1.00 69.87  ? 29  VAL L CA  1 
ATOM 808  C C   . VAL B 2 28  ? -61.756  9.107   -24.510 1.00 75.40  ? 29  VAL L C   1 
ATOM 809  O O   . VAL B 2 28  ? -61.843  8.646   -23.365 1.00 78.24  ? 29  VAL L O   1 
ATOM 810  C CB  . VAL B 2 28  ? -62.334  7.146   -25.990 1.00 67.55  ? 29  VAL L CB  1 
ATOM 811  C CG1 . VAL B 2 28  ? -63.707  7.768   -26.208 1.00 68.58  ? 29  VAL L CG1 1 
ATOM 812  C CG2 . VAL B 2 28  ? -61.903  6.351   -27.210 1.00 51.66  ? 29  VAL L CG2 1 
ATOM 813  N N   . GLY B 2 29  ? -62.042  10.373  -24.805 1.00 76.18  ? 30  GLY L N   1 
ATOM 814  C CA  . GLY B 2 29  ? -62.453  11.318  -23.786 1.00 78.40  ? 30  GLY L CA  1 
ATOM 815  C C   . GLY B 2 29  ? -63.729  10.924  -23.073 1.00 73.43  ? 30  GLY L C   1 
ATOM 816  O O   . GLY B 2 29  ? -64.737  10.610  -23.715 1.00 72.19  ? 30  GLY L O   1 
ATOM 817  N N   . SER B 2 30  ? -63.684  10.925  -21.740 1.00 57.21  ? 31  SER L N   1 
ATOM 818  C CA  . SER B 2 30  ? -64.837  10.651  -20.884 1.00 64.28  ? 31  SER L CA  1 
ATOM 819  C C   . SER B 2 30  ? -65.424  9.262   -21.114 1.00 62.66  ? 31  SER L C   1 
ATOM 820  O O   . SER B 2 30  ? -66.588  9.020   -20.778 1.00 61.32  ? 31  SER L O   1 
ATOM 821  C CB  . SER B 2 30  ? -65.924  11.717  -21.066 1.00 57.31  ? 31  SER L CB  1 
ATOM 822  O OG  . SER B 2 30  ? -65.461  12.990  -20.653 1.00 67.92  ? 31  SER L OG  1 
ATOM 823  N N   . ASN B 2 31  ? -64.633  8.345   -21.677 1.00 69.48  ? 32  ASN L N   1 
ATOM 824  C CA  . ASN B 2 31  ? -65.089  6.988   -21.991 1.00 69.12  ? 32  ASN L CA  1 
ATOM 825  C C   . ASN B 2 31  ? -66.366  7.014   -22.826 1.00 61.73  ? 32  ASN L C   1 
ATOM 826  O O   . ASN B 2 31  ? -67.281  6.212   -22.632 1.00 65.04  ? 32  ASN L O   1 
ATOM 827  C CB  . ASN B 2 31  ? -65.287  6.160   -20.719 1.00 61.67  ? 32  ASN L CB  1 
ATOM 828  C CG  . ASN B 2 31  ? -63.993  5.562   -20.207 1.00 78.45  ? 32  ASN L CG  1 
ATOM 829  O OD1 . ASN B 2 31  ? -63.019  5.431   -20.949 1.00 78.72  ? 32  ASN L OD1 1 
ATOM 830  N ND2 . ASN B 2 31  ? -63.978  5.192   -18.933 1.00 80.21  ? 32  ASN L ND2 1 
ATOM 831  N N   . LEU B 2 32  ? -66.427  7.955   -23.769 1.00 53.79  ? 33  LEU L N   1 
ATOM 832  C CA  . LEU B 2 32  ? -67.606  8.131   -24.614 1.00 49.72  ? 33  LEU L CA  1 
ATOM 833  C C   . LEU B 2 32  ? -67.520  7.142   -25.775 1.00 59.26  ? 33  LEU L C   1 
ATOM 834  O O   . LEU B 2 32  ? -67.132  7.469   -26.899 1.00 50.01  ? 33  LEU L O   1 
ATOM 835  C CB  . LEU B 2 32  ? -67.709  9.573   -25.090 1.00 58.67  ? 33  LEU L CB  1 
ATOM 836  C CG  . LEU B 2 32  ? -67.988  10.614  -24.002 1.00 58.13  ? 33  LEU L CG  1 
ATOM 837  C CD1 . LEU B 2 32  ? -68.201  11.990  -24.609 1.00 61.04  ? 33  LEU L CD1 1 
ATOM 838  C CD2 . LEU B 2 32  ? -69.187  10.214  -23.151 1.00 45.19  ? 33  LEU L CD2 1 
ATOM 839  N N   . LEU B 2 33  ? -67.888  5.899   -25.478 1.00 57.90  ? 34  LEU L N   1 
ATOM 840  C CA  . LEU B 2 33  ? -67.846  4.798   -26.429 1.00 49.20  ? 34  LEU L CA  1 
ATOM 841  C C   . LEU B 2 33  ? -69.236  4.185   -26.517 1.00 53.06  ? 34  LEU L C   1 
ATOM 842  O O   . LEU B 2 33  ? -69.848  3.881   -25.488 1.00 58.53  ? 34  LEU L O   1 
ATOM 843  C CB  . LEU B 2 33  ? -66.812  3.750   -25.992 1.00 54.08  ? 34  LEU L CB  1 
ATOM 844  C CG  . LEU B 2 33  ? -66.244  2.741   -26.996 1.00 53.74  ? 34  LEU L CG  1 
ATOM 845  C CD1 . LEU B 2 33  ? -67.258  1.665   -27.363 1.00 53.93  ? 34  LEU L CD1 1 
ATOM 846  C CD2 . LEU B 2 33  ? -65.740  3.459   -28.237 1.00 60.51  ? 34  LEU L CD2 1 
ATOM 847  N N   . ALA B 2 34  ? -69.727  3.996   -27.739 1.00 43.36  ? 35  ALA L N   1 
ATOM 848  C CA  . ALA B 2 34  ? -71.040  3.421   -27.975 1.00 38.31  ? 35  ALA L CA  1 
ATOM 849  C C   . ALA B 2 34  ? -70.914  2.166   -28.824 1.00 43.58  ? 35  ALA L C   1 
ATOM 850  O O   . ALA B 2 34  ? -70.001  2.037   -29.643 1.00 51.16  ? 35  ALA L O   1 
ATOM 851  C CB  . ALA B 2 34  ? -71.980  4.417   -28.664 1.00 45.92  ? 35  ALA L CB  1 
ATOM 852  N N   . TRP B 2 35  ? -71.835  1.237   -28.599 1.00 41.51  ? 36  TRP L N   1 
ATOM 853  C CA  . TRP B 2 35  ? -71.941  0.007   -29.371 1.00 40.45  ? 36  TRP L CA  1 
ATOM 854  C C   . TRP B 2 35  ? -73.310  -0.042  -30.031 1.00 44.08  ? 36  TRP L C   1 
ATOM 855  O O   . TRP B 2 35  ? -74.332  0.140   -29.357 1.00 49.66  ? 36  TRP L O   1 
ATOM 856  C CB  . TRP B 2 35  ? -71.745  -1.230  -28.490 1.00 46.11  ? 36  TRP L CB  1 
ATOM 857  C CG  . TRP B 2 35  ? -70.337  -1.454  -28.031 1.00 44.61  ? 36  TRP L CG  1 
ATOM 858  C CD1 . TRP B 2 35  ? -69.779  -1.033  -26.858 1.00 54.00  ? 36  TRP L CD1 1 
ATOM 859  C CD2 . TRP B 2 35  ? -69.310  -2.161  -28.732 1.00 44.38  ? 36  TRP L CD2 1 
ATOM 860  N NE1 . TRP B 2 35  ? -68.466  -1.434  -26.788 1.00 56.01  ? 36  TRP L NE1 1 
ATOM 861  C CE2 . TRP B 2 35  ? -68.154  -2.128  -27.927 1.00 42.68  ? 36  TRP L CE2 1 
ATOM 862  C CE3 . TRP B 2 35  ? -69.254  -2.818  -29.965 1.00 46.96  ? 36  TRP L CE3 1 
ATOM 863  C CZ2 . TRP B 2 35  ? -66.958  -2.726  -28.314 1.00 51.71  ? 36  TRP L CZ2 1 
ATOM 864  C CZ3 . TRP B 2 35  ? -68.065  -3.412  -30.349 1.00 48.05  ? 36  TRP L CZ3 1 
ATOM 865  C CH2 . TRP B 2 35  ? -66.934  -3.362  -29.526 1.00 54.22  ? 36  TRP L CH2 1 
ATOM 866  N N   . TYR B 2 36  ? -73.316  -0.292  -31.341 1.00 52.86  ? 37  TYR L N   1 
ATOM 867  C CA  . TYR B 2 36  ? -74.517  -0.470  -32.141 1.00 54.29  ? 37  TYR L CA  1 
ATOM 868  C C   . TYR B 2 36  ? -74.575  -1.891  -32.690 1.00 57.18  ? 37  TYR L C   1 
ATOM 869  O O   . TYR B 2 36  ? -73.549  -2.480  -33.043 1.00 45.99  ? 37  TYR L O   1 
ATOM 870  C CB  . TYR B 2 36  ? -74.562  0.504   -33.325 1.00 39.17  ? 37  TYR L CB  1 
ATOM 871  C CG  . TYR B 2 36  ? -74.523  1.970   -32.969 1.00 40.90  ? 37  TYR L CG  1 
ATOM 872  C CD1 . TYR B 2 36  ? -75.695  2.678   -32.729 1.00 46.06  ? 37  TYR L CD1 1 
ATOM 873  C CD2 . TYR B 2 36  ? -73.317  2.657   -32.917 1.00 34.02  ? 37  TYR L CD2 1 
ATOM 874  C CE1 . TYR B 2 36  ? -75.667  4.024   -32.418 1.00 37.61  ? 37  TYR L CE1 1 
ATOM 875  C CE2 . TYR B 2 36  ? -73.278  4.002   -32.609 1.00 41.38  ? 37  TYR L CE2 1 
ATOM 876  C CZ  . TYR B 2 36  ? -74.456  4.682   -32.360 1.00 48.47  ? 37  TYR L CZ  1 
ATOM 877  O OH  . TYR B 2 36  ? -74.424  6.023   -32.048 1.00 52.03  ? 37  TYR L OH  1 
ATOM 878  N N   . GLN B 2 37  ? -75.789  -2.426  -32.778 1.00 55.08  ? 38  GLN L N   1 
ATOM 879  C CA  . GLN B 2 37  ? -76.060  -3.675  -33.476 1.00 53.64  ? 38  GLN L CA  1 
ATOM 880  C C   . GLN B 2 37  ? -76.789  -3.358  -34.773 1.00 60.40  ? 38  GLN L C   1 
ATOM 881  O O   . GLN B 2 37  ? -77.753  -2.585  -34.771 1.00 60.40  ? 38  GLN L O   1 
ATOM 882  C CB  . GLN B 2 37  ? -76.903  -4.618  -32.617 1.00 53.62  ? 38  GLN L CB  1 
ATOM 883  C CG  . GLN B 2 37  ? -77.752  -5.591  -33.420 1.00 53.09  ? 38  GLN L CG  1 
ATOM 884  C CD  . GLN B 2 37  ? -78.612  -6.476  -32.540 1.00 73.84  ? 38  GLN L CD  1 
ATOM 885  O OE1 . GLN B 2 37  ? -79.803  -6.218  -32.355 1.00 81.01  ? 38  GLN L OE1 1 
ATOM 886  N NE2 . GLN B 2 37  ? -78.011  -7.529  -31.988 1.00 55.96  ? 38  GLN L NE2 1 
ATOM 887  N N   . GLN B 2 38  ? -76.326  -3.940  -35.879 1.00 59.05  ? 39  GLN L N   1 
ATOM 888  C CA  . GLN B 2 38  ? -76.949  -3.747  -37.183 1.00 65.98  ? 39  GLN L CA  1 
ATOM 889  C C   . GLN B 2 38  ? -77.268  -5.105  -37.791 1.00 62.23  ? 39  GLN L C   1 
ATOM 890  O O   . GLN B 2 38  ? -76.369  -5.937  -37.977 1.00 48.90  ? 39  GLN L O   1 
ATOM 891  C CB  . GLN B 2 38  ? -76.043  -2.939  -38.117 1.00 64.60  ? 39  GLN L CB  1 
ATOM 892  C CG  . GLN B 2 38  ? -76.657  -2.632  -39.474 1.00 70.81  ? 39  GLN L CG  1 
ATOM 893  C CD  . GLN B 2 38  ? -75.736  -1.815  -40.363 1.00 66.15  ? 39  GLN L CD  1 
ATOM 894  O OE1 . GLN B 2 38  ? -74.531  -1.735  -40.122 1.00 72.58  ? 39  GLN L OE1 1 
ATOM 895  N NE2 . GLN B 2 38  ? -76.300  -1.200  -41.395 1.00 57.56  ? 39  GLN L NE2 1 
ATOM 896  N N   . LYS B 2 39  ? -78.550  -5.326  -38.083 1.00 53.30  ? 40  LYS L N   1 
ATOM 897  C CA  . LYS B 2 39  ? -79.008  -6.481  -38.833 1.00 68.28  ? 40  LYS L CA  1 
ATOM 898  C C   . LYS B 2 39  ? -78.710  -6.288  -40.316 1.00 78.21  ? 40  LYS L C   1 
ATOM 899  O O   . LYS B 2 39  ? -78.484  -5.162  -40.769 1.00 77.97  ? 40  LYS L O   1 
ATOM 900  C CB  . LYS B 2 39  ? -80.507  -6.684  -38.625 1.00 67.58  ? 40  LYS L CB  1 
ATOM 901  C CG  . LYS B 2 39  ? -80.882  -7.600  -37.470 1.00 88.16  ? 40  LYS L CG  1 
ATOM 902  C CD  . LYS B 2 39  ? -80.762  -6.883  -36.133 1.00 95.00  ? 40  LYS L CD  1 
ATOM 903  C CE  . LYS B 2 39  ? -81.194  -7.776  -34.983 1.00 83.85  ? 40  LYS L CE  1 
ATOM 904  N NZ  . LYS B 2 39  ? -82.590  -8.267  -35.158 1.00 72.75  ? 40  LYS L NZ  1 
ATOM 905  N N   . PRO B 2 40  ? -78.688  -7.370  -41.095 1.00 85.90  ? 41  PRO L N   1 
ATOM 906  C CA  . PRO B 2 40  ? -78.472  -7.228  -42.544 1.00 78.71  ? 41  PRO L CA  1 
ATOM 907  C C   . PRO B 2 40  ? -79.532  -6.344  -43.185 1.00 79.95  ? 41  PRO L C   1 
ATOM 908  O O   . PRO B 2 40  ? -80.732  -6.621  -43.109 1.00 69.41  ? 41  PRO L O   1 
ATOM 909  C CB  . PRO B 2 40  ? -78.551  -8.672  -43.052 1.00 85.69  ? 41  PRO L CB  1 
ATOM 910  C CG  . PRO B 2 40  ? -78.147  -9.500  -41.881 1.00 93.75  ? 41  PRO L CG  1 
ATOM 911  C CD  . PRO B 2 40  ? -78.675  -8.782  -40.672 1.00 81.34  ? 41  PRO L CD  1 
ATOM 912  N N   . GLY B 2 41  ? -79.074  -5.266  -43.815 1.00 76.29  ? 42  GLY L N   1 
ATOM 913  C CA  . GLY B 2 41  ? -79.951  -4.383  -44.565 1.00 63.09  ? 42  GLY L CA  1 
ATOM 914  C C   . GLY B 2 41  ? -80.978  -3.608  -43.766 1.00 69.54  ? 42  GLY L C   1 
ATOM 915  O O   . GLY B 2 41  ? -82.143  -3.533  -44.178 1.00 61.89  ? 42  GLY L O   1 
ATOM 916  N N   . GLN B 2 42  ? -80.584  -3.031  -42.634 1.00 84.94  ? 43  GLN L N   1 
ATOM 917  C CA  . GLN B 2 42  ? -81.451  -2.105  -41.913 1.00 74.83  ? 43  GLN L CA  1 
ATOM 918  C C   . GLN B 2 42  ? -80.581  -1.208  -41.040 1.00 62.13  ? 43  GLN L C   1 
ATOM 919  O O   . GLN B 2 42  ? -79.359  -1.369  -40.970 1.00 51.14  ? 43  GLN L O   1 
ATOM 920  C CB  . GLN B 2 42  ? -82.516  -2.840  -41.093 1.00 65.41  ? 43  GLN L CB  1 
ATOM 921  C CG  . GLN B 2 42  ? -81.996  -3.670  -39.940 1.00 71.47  ? 43  GLN L CG  1 
ATOM 922  C CD  . GLN B 2 42  ? -83.121  -4.340  -39.170 1.00 83.09  ? 43  GLN L CD  1 
ATOM 923  O OE1 . GLN B 2 42  ? -84.195  -4.596  -39.716 1.00 69.43  ? 43  GLN L OE1 1 
ATOM 924  N NE2 . GLN B 2 42  ? -82.888  -4.609  -37.890 1.00 94.99  ? 43  GLN L NE2 1 
ATOM 925  N N   . ALA B 2 43  ? -81.227  -0.245  -40.386 1.00 59.78  ? 44  ALA L N   1 
ATOM 926  C CA  . ALA B 2 43  ? -80.504  0.762   -39.627 1.00 64.95  ? 44  ALA L CA  1 
ATOM 927  C C   . ALA B 2 43  ? -79.887  0.161   -38.364 1.00 57.92  ? 44  ALA L C   1 
ATOM 928  O O   . ALA B 2 43  ? -80.433  -0.779  -37.780 1.00 59.48  ? 44  ALA L O   1 
ATOM 929  C CB  . ALA B 2 43  ? -81.432  1.913   -39.251 1.00 67.48  ? 44  ALA L CB  1 
ATOM 930  N N   . PRO B 2 44  ? -78.747  0.690   -37.923 1.00 50.85  ? 45  PRO L N   1 
ATOM 931  C CA  . PRO B 2 44  ? -78.153  0.219   -36.667 1.00 62.79  ? 45  PRO L CA  1 
ATOM 932  C C   . PRO B 2 44  ? -79.051  0.508   -35.472 1.00 56.64  ? 45  PRO L C   1 
ATOM 933  O O   . PRO B 2 44  ? -79.811  1.479   -35.454 1.00 55.01  ? 45  PRO L O   1 
ATOM 934  C CB  . PRO B 2 44  ? -76.836  1.003   -36.579 1.00 55.20  ? 45  PRO L CB  1 
ATOM 935  C CG  . PRO B 2 44  ? -76.542  1.409   -37.993 1.00 51.75  ? 45  PRO L CG  1 
ATOM 936  C CD  . PRO B 2 44  ? -77.883  1.666   -38.610 1.00 51.99  ? 45  PRO L CD  1 
ATOM 937  N N   . ARG B 2 45  ? -78.962  -0.366  -34.473 1.00 54.56  ? 46  ARG L N   1 
ATOM 938  C CA  . ARG B 2 45  ? -79.682  -0.228  -33.214 1.00 54.13  ? 46  ARG L CA  1 
ATOM 939  C C   . ARG B 2 45  ? -78.677  0.026   -32.100 1.00 46.20  ? 46  ARG L C   1 
ATOM 940  O O   . ARG B 2 45  ? -77.703  -0.720  -31.959 1.00 48.25  ? 46  ARG L O   1 
ATOM 941  C CB  . ARG B 2 45  ? -80.509  -1.484  -32.916 1.00 56.35  ? 46  ARG L CB  1 
ATOM 942  C CG  . ARG B 2 45  ? -81.568  -1.312  -31.831 1.00 68.98  ? 46  ARG L CG  1 
ATOM 943  C CD  . ARG B 2 45  ? -82.336  -2.610  -31.586 1.00 79.64  ? 46  ARG L CD  1 
ATOM 944  N NE  . ARG B 2 45  ? -81.585  -3.551  -30.762 1.00 100.16 ? 46  ARG L NE  1 
ATOM 945  C CZ  . ARG B 2 45  ? -82.080  -4.676  -30.261 1.00 93.59  ? 46  ARG L CZ  1 
ATOM 946  N NH1 . ARG B 2 45  ? -83.339  -5.029  -30.465 1.00 106.12 ? 46  ARG L NH1 1 
ATOM 947  N NH2 . ARG B 2 45  ? -81.293  -5.466  -29.536 1.00 64.61  ? 46  ARG L NH2 1 
ATOM 948  N N   . LEU B 2 46  ? -78.907  1.081   -31.322 1.00 50.64  ? 47  LEU L N   1 
ATOM 949  C CA  . LEU B 2 46  ? -77.986  1.423   -30.244 1.00 57.45  ? 47  LEU L CA  1 
ATOM 950  C C   . LEU B 2 46  ? -78.086  0.411   -29.110 1.00 49.14  ? 47  LEU L C   1 
ATOM 951  O O   . LEU B 2 46  ? -79.171  0.160   -28.577 1.00 46.79  ? 47  LEU L O   1 
ATOM 952  C CB  . LEU B 2 46  ? -78.274  2.825   -29.714 1.00 55.05  ? 47  LEU L CB  1 
ATOM 953  C CG  . LEU B 2 46  ? -77.401  3.269   -28.538 1.00 39.99  ? 47  LEU L CG  1 
ATOM 954  C CD1 . LEU B 2 46  ? -75.923  3.273   -28.911 1.00 35.18  ? 47  LEU L CD1 1 
ATOM 955  C CD2 . LEU B 2 46  ? -77.836  4.637   -28.040 1.00 46.98  ? 47  LEU L CD2 1 
ATOM 956  N N   . LEU B 2 47  ? -76.943  -0.160  -28.737 1.00 43.95  ? 48  LEU L N   1 
ATOM 957  C CA  . LEU B 2 47  ? -76.860  -1.124  -27.648 1.00 40.81  ? 48  LEU L CA  1 
ATOM 958  C C   . LEU B 2 47  ? -76.292  -0.510  -26.377 1.00 56.24  ? 48  LEU L C   1 
ATOM 959  O O   . LEU B 2 47  ? -76.926  -0.573  -25.318 1.00 48.95  ? 48  LEU L O   1 
ATOM 960  C CB  . LEU B 2 47  ? -75.995  -2.319  -28.063 1.00 43.59  ? 48  LEU L CB  1 
ATOM 961  C CG  . LEU B 2 47  ? -76.539  -3.310  -29.088 1.00 41.88  ? 48  LEU L CG  1 
ATOM 962  C CD1 . LEU B 2 47  ? -75.524  -4.418  -29.302 1.00 50.72  ? 48  LEU L CD1 1 
ATOM 963  C CD2 . LEU B 2 47  ? -77.878  -3.873  -28.645 1.00 47.93  ? 48  LEU L CD2 1 
ATOM 964  N N   . ILE B 2 48  ? -75.105  0.087   -26.464 1.00 46.24  ? 49  ILE L N   1 
ATOM 965  C CA  . ILE B 2 48  ? -74.405  0.610   -25.294 1.00 56.03  ? 49  ILE L CA  1 
ATOM 966  C C   . ILE B 2 48  ? -74.016  2.059   -25.547 1.00 49.03  ? 49  ILE L C   1 
ATOM 967  O O   . ILE B 2 48  ? -73.597  2.409   -26.654 1.00 61.16  ? 49  ILE L O   1 
ATOM 968  C CB  . ILE B 2 48  ? -73.153  -0.229  -24.950 1.00 59.25  ? 49  ILE L CB  1 
ATOM 969  C CG1 . ILE B 2 48  ? -73.498  -1.716  -24.864 1.00 56.92  ? 49  ILE L CG1 1 
ATOM 970  C CG2 . ILE B 2 48  ? -72.547  0.227   -23.631 1.00 54.25  ? 49  ILE L CG2 1 
ATOM 971  C CD1 . ILE B 2 48  ? -74.424  -2.049  -23.718 1.00 37.49  ? 49  ILE L CD1 1 
ATOM 972  N N   . TYR B 2 49  ? -74.152  2.898   -24.519 1.00 52.22  ? 50  TYR L N   1 
ATOM 973  C CA  . TYR B 2 49  ? -73.632  4.258   -24.536 1.00 51.67  ? 50  TYR L CA  1 
ATOM 974  C C   . TYR B 2 49  ? -72.807  4.491   -23.278 1.00 49.89  ? 50  TYR L C   1 
ATOM 975  O O   . TYR B 2 49  ? -73.085  3.921   -22.221 1.00 59.99  ? 50  TYR L O   1 
ATOM 976  C CB  . TYR B 2 49  ? -74.754  5.310   -24.633 1.00 40.85  ? 50  TYR L CB  1 
ATOM 977  C CG  . TYR B 2 49  ? -75.593  5.460   -23.383 1.00 50.42  ? 50  TYR L CG  1 
ATOM 978  C CD1 . TYR B 2 49  ? -76.678  4.627   -23.146 1.00 54.87  ? 50  TYR L CD1 1 
ATOM 979  C CD2 . TYR B 2 49  ? -75.302  6.442   -22.442 1.00 61.69  ? 50  TYR L CD2 1 
ATOM 980  C CE1 . TYR B 2 49  ? -77.449  4.766   -22.005 1.00 60.57  ? 50  TYR L CE1 1 
ATOM 981  C CE2 . TYR B 2 49  ? -76.066  6.587   -21.297 1.00 53.81  ? 50  TYR L CE2 1 
ATOM 982  C CZ  . TYR B 2 49  ? -77.138  5.748   -21.086 1.00 59.39  ? 50  TYR L CZ  1 
ATOM 983  O OH  . TYR B 2 49  ? -77.898  5.889   -19.949 1.00 72.17  ? 50  TYR L OH  1 
ATOM 984  N N   . GLY B 2 50  ? -71.782  5.331   -23.402 1.00 44.75  ? 51  GLY L N   1 
ATOM 985  C CA  . GLY B 2 50  ? -70.881  5.560   -22.292 1.00 44.73  ? 51  GLY L CA  1 
ATOM 986  C C   . GLY B 2 50  ? -69.963  4.405   -21.969 1.00 55.99  ? 51  GLY L C   1 
ATOM 987  O O   . GLY B 2 50  ? -69.380  4.386   -20.882 1.00 62.92  ? 51  GLY L O   1 
ATOM 988  N N   . ALA B 2 51  ? -69.857  3.423   -22.869 1.00 59.62  ? 52  ALA L N   1 
ATOM 989  C CA  . ALA B 2 51  ? -68.964  2.269   -22.769 1.00 58.87  ? 52  ALA L CA  1 
ATOM 990  C C   . ALA B 2 51  ? -69.426  1.246   -21.739 1.00 51.84  ? 52  ALA L C   1 
ATOM 991  O O   . ALA B 2 51  ? -68.883  0.140   -21.683 1.00 73.40  ? 52  ALA L O   1 
ATOM 992  C CB  . ALA B 2 51  ? -67.532  2.709   -22.447 1.00 49.11  ? 52  ALA L CB  1 
ATOM 993  N N   . SER B 2 52  ? -70.424  1.591   -20.925 1.00 53.07  ? 53  SER L N   1 
ATOM 994  C CA  . SER B 2 52  ? -70.954  0.638   -19.954 1.00 49.67  ? 53  SER L CA  1 
ATOM 995  C C   . SER B 2 52  ? -72.464  0.679   -19.777 1.00 44.67  ? 53  SER L C   1 
ATOM 996  O O   . SER B 2 52  ? -73.021  -0.289  -19.249 1.00 55.49  ? 53  SER L O   1 
ATOM 997  C CB  . SER B 2 52  ? -70.282  0.839   -18.587 1.00 45.65  ? 53  SER L CB  1 
ATOM 998  O OG  . SER B 2 52  ? -70.431  2.169   -18.122 1.00 80.19  ? 53  SER L OG  1 
ATOM 999  N N   . ASN B 2 53  ? -73.157  1.725   -20.217 1.00 43.41  ? 54  ASN L N   1 
ATOM 1000 C CA  . ASN B 2 53  ? -74.586  1.885   -19.972 1.00 42.22  ? 54  ASN L CA  1 
ATOM 1001 C C   . ASN B 2 53  ? -75.368  1.350   -21.163 1.00 51.14  ? 54  ASN L C   1 
ATOM 1002 O O   . ASN B 2 53  ? -75.141  1.773   -22.302 1.00 54.75  ? 54  ASN L O   1 
ATOM 1003 C CB  . ASN B 2 53  ? -74.938  3.351   -19.721 1.00 46.63  ? 54  ASN L CB  1 
ATOM 1004 C CG  . ASN B 2 53  ? -74.109  3.966   -18.618 1.00 54.51  ? 54  ASN L CG  1 
ATOM 1005 O OD1 . ASN B 2 53  ? -74.410  3.799   -17.436 1.00 73.09  ? 54  ASN L OD1 1 
ATOM 1006 N ND2 . ASN B 2 53  ? -73.051  4.675   -18.996 1.00 51.33  ? 54  ASN L ND2 1 
ATOM 1007 N N   . ARG B 2 54  ? -76.287  0.428   -20.900 1.00 37.32  ? 55  ARG L N   1 
ATOM 1008 C CA  . ARG B 2 54  ? -77.097  -0.142  -21.962 1.00 54.10  ? 55  ARG L CA  1 
ATOM 1009 C C   . ARG B 2 54  ? -78.363  0.685   -22.155 1.00 50.12  ? 55  ARG L C   1 
ATOM 1010 O O   . ARG B 2 54  ? -78.913  1.252   -21.208 1.00 46.65  ? 55  ARG L O   1 
ATOM 1011 C CB  . ARG B 2 54  ? -77.426  -1.607  -21.660 1.00 41.02  ? 55  ARG L CB  1 
ATOM 1012 C CG  . ARG B 2 54  ? -78.753  -1.866  -20.999 1.00 54.07  ? 55  ARG L CG  1 
ATOM 1013 C CD  . ARG B 2 54  ? -79.080  -3.351  -21.059 1.00 64.16  ? 55  ARG L CD  1 
ATOM 1014 N NE  . ARG B 2 54  ? -78.042  -4.153  -20.421 1.00 67.35  ? 55  ARG L NE  1 
ATOM 1015 C CZ  . ARG B 2 54  ? -77.942  -4.349  -19.112 1.00 75.31  ? 55  ARG L CZ  1 
ATOM 1016 N NH1 . ARG B 2 54  ? -78.797  -3.803  -18.261 1.00 57.13  ? 55  ARG L NH1 1 
ATOM 1017 N NH2 . ARG B 2 54  ? -76.954  -5.109  -18.644 1.00 62.88  ? 55  ARG L NH2 1 
ATOM 1018 N N   . ALA B 2 55  ? -78.802  0.774   -23.407 1.00 66.61  ? 56  ALA L N   1 
ATOM 1019 C CA  . ALA B 2 55  ? -79.892  1.663   -23.774 1.00 53.26  ? 56  ALA L CA  1 
ATOM 1020 C C   . ALA B 2 55  ? -81.231  1.088   -23.316 1.00 57.19  ? 56  ALA L C   1 
ATOM 1021 O O   . ALA B 2 55  ? -81.310  0.009   -22.721 1.00 68.97  ? 56  ALA L O   1 
ATOM 1022 C CB  . ALA B 2 55  ? -79.884  1.915   -25.280 1.00 51.98  ? 56  ALA L CB  1 
ATOM 1023 N N   . THR B 2 56  ? -82.300  1.827   -23.598 1.00 62.76  ? 57  THR L N   1 
ATOM 1024 C CA  . THR B 2 56  ? -83.636  1.415   -23.187 1.00 65.30  ? 57  THR L CA  1 
ATOM 1025 C C   . THR B 2 56  ? -84.111  0.241   -24.033 1.00 69.57  ? 57  THR L C   1 
ATOM 1026 O O   . THR B 2 56  ? -83.963  0.244   -25.259 1.00 65.94  ? 57  THR L O   1 
ATOM 1027 C CB  . THR B 2 56  ? -84.615  2.581   -23.315 1.00 59.74  ? 57  THR L CB  1 
ATOM 1028 O OG1 . THR B 2 56  ? -84.062  3.747   -22.693 1.00 80.01  ? 57  THR L OG1 1 
ATOM 1029 C CG2 . THR B 2 56  ? -85.938  2.238   -22.649 1.00 65.01  ? 57  THR L CG2 1 
ATOM 1030 N N   . GLY B 2 57  ? -84.682  -0.768  -23.374 1.00 66.19  ? 58  GLY L N   1 
ATOM 1031 C CA  . GLY B 2 57  ? -85.243  -1.914  -24.055 1.00 66.83  ? 58  GLY L CA  1 
ATOM 1032 C C   . GLY B 2 57  ? -84.245  -2.957  -24.500 1.00 64.83  ? 58  GLY L C   1 
ATOM 1033 O O   . GLY B 2 57  ? -84.660  -4.023  -24.972 1.00 74.63  ? 58  GLY L O   1 
ATOM 1034 N N   . ILE B 2 58  ? -82.953  -2.697  -24.367 1.00 64.44  ? 59  ILE L N   1 
ATOM 1035 C CA  . ILE B 2 58  ? -81.939  -3.669  -24.775 1.00 67.16  ? 59  ILE L CA  1 
ATOM 1036 C C   . ILE B 2 58  ? -81.872  -4.777  -23.729 1.00 61.02  ? 59  ILE L C   1 
ATOM 1037 O O   . ILE B 2 58  ? -81.773  -4.477  -22.529 1.00 74.83  ? 59  ILE L O   1 
ATOM 1038 C CB  . ILE B 2 58  ? -80.583  -2.991  -24.945 1.00 72.67  ? 59  ILE L CB  1 
ATOM 1039 C CG1 . ILE B 2 58  ? -80.626  -2.012  -26.122 1.00 62.11  ? 59  ILE L CG1 1 
ATOM 1040 C CG2 . ILE B 2 58  ? -79.485  -4.028  -25.142 1.00 61.57  ? 59  ILE L CG2 1 
ATOM 1041 C CD1 . ILE B 2 58  ? -81.101  -2.633  -27.418 1.00 58.42  ? 59  ILE L CD1 1 
ATOM 1042 N N   . PRO B 2 59  ? -81.935  -6.047  -24.129 1.00 65.86  ? 60  PRO L N   1 
ATOM 1043 C CA  . PRO B 2 59  ? -81.822  -7.135  -23.152 1.00 78.12  ? 60  PRO L CA  1 
ATOM 1044 C C   . PRO B 2 59  ? -80.501  -7.072  -22.401 1.00 72.48  ? 60  PRO L C   1 
ATOM 1045 O O   . PRO B 2 59  ? -79.474  -6.646  -22.934 1.00 75.93  ? 60  PRO L O   1 
ATOM 1046 C CB  . PRO B 2 59  ? -81.916  -8.399  -24.013 1.00 74.92  ? 60  PRO L CB  1 
ATOM 1047 C CG  . PRO B 2 59  ? -82.640  -7.966  -25.241 1.00 64.85  ? 60  PRO L CG  1 
ATOM 1048 C CD  . PRO B 2 59  ? -82.208  -6.549  -25.486 1.00 69.60  ? 60  PRO L CD  1 
ATOM 1049 N N   . ASP B 2 60  ? -80.539  -7.499  -21.139 1.00 75.54  ? 61  ASP L N   1 
ATOM 1050 C CA  . ASP B 2 60  ? -79.358  -7.426  -20.287 1.00 81.62  ? 61  ASP L CA  1 
ATOM 1051 C C   . ASP B 2 60  ? -78.260  -8.398  -20.701 1.00 74.87  ? 61  ASP L C   1 
ATOM 1052 O O   . ASP B 2 60  ? -77.181  -8.366  -20.099 1.00 81.34  ? 61  ASP L O   1 
ATOM 1053 C CB  . ASP B 2 60  ? -79.747  -7.663  -18.824 1.00 80.62  ? 61  ASP L CB  1 
ATOM 1054 C CG  . ASP B 2 60  ? -80.717  -8.813  -18.654 1.00 97.30  ? 61  ASP L CG  1 
ATOM 1055 O OD1 . ASP B 2 60  ? -81.339  -9.222  -19.658 1.00 104.40 ? 61  ASP L OD1 1 
ATOM 1056 O OD2 . ASP B 2 60  ? -80.861  -9.305  -17.514 1.00 102.52 ? 61  ASP L OD2 1 
ATOM 1057 N N   . ARG B 2 61  ? -78.499  -9.258  -21.697 1.00 62.30  ? 62  ARG L N   1 
ATOM 1058 C CA  . ARG B 2 61  ? -77.428  -10.104 -22.210 1.00 56.88  ? 62  ARG L CA  1 
ATOM 1059 C C   . ARG B 2 61  ? -76.324  -9.293  -22.880 1.00 59.09  ? 62  ARG L C   1 
ATOM 1060 O O   . ARG B 2 61  ? -75.203  -9.794  -23.019 1.00 59.44  ? 62  ARG L O   1 
ATOM 1061 C CB  . ARG B 2 61  ? -77.987  -11.143 -23.189 1.00 58.10  ? 62  ARG L CB  1 
ATOM 1062 C CG  . ARG B 2 61  ? -78.235  -10.620 -24.599 1.00 66.08  ? 62  ARG L CG  1 
ATOM 1063 C CD  . ARG B 2 61  ? -78.631  -11.738 -25.557 1.00 51.09  ? 62  ARG L CD  1 
ATOM 1064 N NE  . ARG B 2 61  ? -80.078  -11.834 -25.708 1.00 69.34  ? 62  ARG L NE  1 
ATOM 1065 C CZ  . ARG B 2 61  ? -80.757  -11.393 -26.757 1.00 56.42  ? 62  ARG L CZ  1 
ATOM 1066 N NH1 . ARG B 2 61  ? -80.148  -10.821 -27.782 1.00 77.93  ? 62  ARG L NH1 1 
ATOM 1067 N NH2 . ARG B 2 61  ? -82.079  -11.529 -26.779 1.00 61.62  ? 62  ARG L NH2 1 
ATOM 1068 N N   . PHE B 2 62  ? -76.611  -8.060  -23.294 1.00 51.70  ? 63  PHE L N   1 
ATOM 1069 C CA  . PHE B 2 62  ? -75.600  -7.174  -23.855 1.00 47.79  ? 63  PHE L CA  1 
ATOM 1070 C C   . PHE B 2 62  ? -75.016  -6.312  -22.746 1.00 47.39  ? 63  PHE L C   1 
ATOM 1071 O O   . PHE B 2 62  ? -75.758  -5.667  -22.000 1.00 52.48  ? 63  PHE L O   1 
ATOM 1072 C CB  . PHE B 2 62  ? -76.192  -6.278  -24.944 1.00 52.33  ? 63  PHE L CB  1 
ATOM 1073 C CG  . PHE B 2 62  ? -76.790  -7.030  -26.091 1.00 54.47  ? 63  PHE L CG  1 
ATOM 1074 C CD1 . PHE B 2 62  ? -76.013  -7.403  -27.175 1.00 52.64  ? 63  PHE L CD1 1 
ATOM 1075 C CD2 . PHE B 2 62  ? -78.135  -7.356  -26.091 1.00 54.75  ? 63  PHE L CD2 1 
ATOM 1076 C CE1 . PHE B 2 62  ? -76.566  -8.097  -28.230 1.00 52.25  ? 63  PHE L CE1 1 
ATOM 1077 C CE2 . PHE B 2 62  ? -78.692  -8.046  -27.146 1.00 60.66  ? 63  PHE L CE2 1 
ATOM 1078 C CZ  . PHE B 2 62  ? -77.908  -8.418  -28.217 1.00 47.75  ? 63  PHE L CZ  1 
ATOM 1079 N N   . SER B 2 63  ? -73.690  -6.293  -22.645 1.00 50.08  ? 64  SER L N   1 
ATOM 1080 C CA  . SER B 2 63  ? -73.026  -5.467  -21.650 1.00 49.20  ? 64  SER L CA  1 
ATOM 1081 C C   . SER B 2 63  ? -71.760  -4.876  -22.254 1.00 53.88  ? 64  SER L C   1 
ATOM 1082 O O   . SER B 2 63  ? -71.192  -5.412  -23.209 1.00 50.69  ? 64  SER L O   1 
ATOM 1083 C CB  . SER B 2 63  ? -72.707  -6.263  -20.372 1.00 46.03  ? 64  SER L CB  1 
ATOM 1084 O OG  . SER B 2 63  ? -71.735  -7.266  -20.605 1.00 57.83  ? 64  SER L OG  1 
ATOM 1085 N N   . GLY B 2 64  ? -71.333  -3.753  -21.692 1.00 46.95  ? 65  GLY L N   1 
ATOM 1086 C CA  . GLY B 2 64  ? -70.131  -3.088  -22.147 1.00 45.99  ? 65  GLY L CA  1 
ATOM 1087 C C   . GLY B 2 64  ? -69.181  -2.829  -20.998 1.00 52.27  ? 65  GLY L C   1 
ATOM 1088 O O   . GLY B 2 64  ? -69.592  -2.611  -19.859 1.00 75.85  ? 65  GLY L O   1 
ATOM 1089 N N   . SER B 2 65  ? -67.891  -2.853  -21.318 1.00 49.48  ? 66  SER L N   1 
ATOM 1090 C CA  . SER B 2 65  ? -66.854  -2.594  -20.331 1.00 54.67  ? 66  SER L CA  1 
ATOM 1091 C C   . SER B 2 65  ? -65.651  -1.987  -21.036 1.00 51.76  ? 66  SER L C   1 
ATOM 1092 O O   . SER B 2 65  ? -65.599  -1.913  -22.263 1.00 69.15  ? 66  SER L O   1 
ATOM 1093 C CB  . SER B 2 65  ? -66.461  -3.872  -19.584 1.00 58.10  ? 66  SER L CB  1 
ATOM 1094 O OG  . SER B 2 65  ? -66.156  -4.913  -20.494 1.00 78.88  ? 66  SER L OG  1 
ATOM 1095 N N   . GLY B 2 66  ? -64.682  -1.550  -20.246 1.00 62.26  ? 67  GLY L N   1 
ATOM 1096 C CA  . GLY B 2 66  ? -63.429  -1.039  -20.767 1.00 71.19  ? 67  GLY L CA  1 
ATOM 1097 C C   . GLY B 2 66  ? -63.227  0.430   -20.438 1.00 67.79  ? 67  GLY L C   1 
ATOM 1098 O O   . GLY B 2 66  ? -64.103  1.113   -19.907 1.00 73.53  ? 67  GLY L O   1 
ATOM 1099 N N   . SER B 2 67  ? -62.034  0.904   -20.784 1.00 61.25  ? 68  SER L N   1 
ATOM 1100 C CA  . SER B 2 67  ? -61.655  2.282   -20.509 1.00 69.95  ? 68  SER L CA  1 
ATOM 1101 C C   . SER B 2 67  ? -60.507  2.676   -21.428 1.00 75.14  ? 68  SER L C   1 
ATOM 1102 O O   . SER B 2 67  ? -59.875  1.832   -22.074 1.00 82.14  ? 68  SER L O   1 
ATOM 1103 C CB  . SER B 2 67  ? -61.267  2.474   -19.040 1.00 75.39  ? 68  SER L CB  1 
ATOM 1104 O OG  . SER B 2 67  ? -60.840  3.803   -18.800 1.00 94.92  ? 68  SER L OG  1 
ATOM 1105 N N   . GLY B 2 68  ? -60.270  3.986   -21.496 1.00 76.29  ? 69  GLY L N   1 
ATOM 1106 C CA  . GLY B 2 68  ? -59.129  4.529   -22.202 1.00 77.91  ? 69  GLY L CA  1 
ATOM 1107 C C   . GLY B 2 68  ? -59.057  4.110   -23.653 1.00 81.00  ? 69  GLY L C   1 
ATOM 1108 O O   . GLY B 2 68  ? -59.829  4.578   -24.495 1.00 76.08  ? 69  GLY L O   1 
ATOM 1109 N N   . THR B 2 69  ? -58.116  3.217   -23.947 1.00 86.16  ? 70  THR L N   1 
ATOM 1110 C CA  . THR B 2 69  ? -57.895  2.716   -25.295 1.00 74.34  ? 70  THR L CA  1 
ATOM 1111 C C   . THR B 2 69  ? -58.787  1.526   -25.633 1.00 77.91  ? 70  THR L C   1 
ATOM 1112 O O   . THR B 2 69  ? -59.267  1.418   -26.767 1.00 86.12  ? 70  THR L O   1 
ATOM 1113 C CB  . THR B 2 69  ? -56.418  2.336   -25.465 1.00 83.37  ? 70  THR L CB  1 
ATOM 1114 O OG1 . THR B 2 69  ? -55.628  3.525   -25.587 1.00 96.70  ? 70  THR L OG1 1 
ATOM 1115 C CG2 . THR B 2 69  ? -56.208  1.472   -26.697 1.00 96.81  ? 70  THR L CG2 1 
ATOM 1116 N N   . ASP B 2 70  ? -59.051  0.642   -24.672 1.00 76.53  ? 71  ASP L N   1 
ATOM 1117 C CA  . ASP B 2 70  ? -59.634  -0.664  -24.961 1.00 78.76  ? 71  ASP L CA  1 
ATOM 1118 C C   . ASP B 2 70  ? -61.035  -0.777  -24.374 1.00 65.99  ? 71  ASP L C   1 
ATOM 1119 O O   . ASP B 2 70  ? -61.239  -0.489  -23.191 1.00 81.15  ? 71  ASP L O   1 
ATOM 1120 C CB  . ASP B 2 70  ? -58.747  -1.784  -24.414 1.00 78.14  ? 71  ASP L CB  1 
ATOM 1121 C CG  . ASP B 2 70  ? -59.410  -3.146  -24.500 1.00 102.78 ? 71  ASP L CG  1 
ATOM 1122 O OD1 . ASP B 2 70  ? -59.539  -3.678  -25.624 1.00 105.60 ? 71  ASP L OD1 1 
ATOM 1123 O OD2 . ASP B 2 70  ? -59.806  -3.682  -23.443 1.00 111.39 ? 71  ASP L OD2 1 
ATOM 1124 N N   . PHE B 2 71  ? -61.986  -1.232  -25.192 1.00 64.62  ? 72  PHE L N   1 
ATOM 1125 C CA  . PHE B 2 71  ? -63.360  -1.448  -24.765 1.00 63.14  ? 72  PHE L CA  1 
ATOM 1126 C C   . PHE B 2 71  ? -63.845  -2.793  -25.290 1.00 65.89  ? 72  PHE L C   1 
ATOM 1127 O O   . PHE B 2 71  ? -63.331  -3.321  -26.278 1.00 62.99  ? 72  PHE L O   1 
ATOM 1128 C CB  . PHE B 2 71  ? -64.286  -0.329  -25.256 1.00 69.19  ? 72  PHE L CB  1 
ATOM 1129 C CG  . PHE B 2 71  ? -63.852  1.042   -24.832 1.00 70.28  ? 72  PHE L CG  1 
ATOM 1130 C CD1 . PHE B 2 71  ? -64.253  1.566   -23.616 1.00 57.52  ? 72  PHE L CD1 1 
ATOM 1131 C CD2 . PHE B 2 71  ? -63.038  1.808   -25.652 1.00 67.61  ? 72  PHE L CD2 1 
ATOM 1132 C CE1 . PHE B 2 71  ? -63.853  2.829   -23.225 1.00 63.30  ? 72  PHE L CE1 1 
ATOM 1133 C CE2 . PHE B 2 71  ? -62.632  3.069   -25.265 1.00 69.42  ? 72  PHE L CE2 1 
ATOM 1134 C CZ  . PHE B 2 71  ? -63.041  3.580   -24.049 1.00 67.86  ? 72  PHE L CZ  1 
ATOM 1135 N N   . THR B 2 72  ? -64.853  -3.342  -24.617 1.00 68.89  ? 73  THR L N   1 
ATOM 1136 C CA  . THR B 2 72  ? -65.335  -4.684  -24.898 1.00 61.53  ? 73  THR L CA  1 
ATOM 1137 C C   . THR B 2 72  ? -66.851  -4.731  -24.802 1.00 57.96  ? 73  THR L C   1 
ATOM 1138 O O   . THR B 2 72  ? -67.443  -4.180  -23.869 1.00 72.73  ? 73  THR L O   1 
ATOM 1139 C CB  . THR B 2 72  ? -64.731  -5.703  -23.923 1.00 65.51  ? 73  THR L CB  1 
ATOM 1140 O OG1 . THR B 2 72  ? -63.302  -5.600  -23.944 1.00 89.49  ? 73  THR L OG1 1 
ATOM 1141 C CG2 . THR B 2 72  ? -65.138  -7.113  -24.311 1.00 64.56  ? 73  THR L CG2 1 
ATOM 1142 N N   . LEU B 2 73  ? -67.470  -5.398  -25.771 1.00 52.32  ? 74  LEU L N   1 
ATOM 1143 C CA  . LEU B 2 73  ? -68.894  -5.706  -25.747 1.00 48.53  ? 74  LEU L CA  1 
ATOM 1144 C C   . LEU B 2 73  ? -69.060  -7.207  -25.552 1.00 59.55  ? 74  LEU L C   1 
ATOM 1145 O O   . LEU B 2 73  ? -68.497  -8.003  -26.312 1.00 63.86  ? 74  LEU L O   1 
ATOM 1146 C CB  . LEU B 2 73  ? -69.583  -5.259  -27.040 1.00 47.62  ? 74  LEU L CB  1 
ATOM 1147 C CG  . LEU B 2 73  ? -71.036  -5.709  -27.232 1.00 36.59  ? 74  LEU L CG  1 
ATOM 1148 C CD1 . LEU B 2 73  ? -71.957  -4.934  -26.309 1.00 51.02  ? 74  LEU L CD1 1 
ATOM 1149 C CD2 . LEU B 2 73  ? -71.480  -5.548  -28.675 1.00 47.48  ? 74  LEU L CD2 1 
ATOM 1150 N N   . THR B 2 74  ? -69.822  -7.593  -24.532 1.00 52.64  ? 75  THR L N   1 
ATOM 1151 C CA  . THR B 2 74  ? -70.033  -8.997  -24.213 1.00 55.59  ? 75  THR L CA  1 
ATOM 1152 C C   . THR B 2 74  ? -71.507  -9.348  -24.354 1.00 59.64  ? 75  THR L C   1 
ATOM 1153 O O   . THR B 2 74  ? -72.382  -8.606  -23.891 1.00 46.60  ? 75  THR L O   1 
ATOM 1154 C CB  . THR B 2 74  ? -69.541  -9.340  -22.802 1.00 38.20  ? 75  THR L CB  1 
ATOM 1155 O OG1 . THR B 2 74  ? -70.198  -8.504  -21.844 1.00 73.23  ? 75  THR L OG1 1 
ATOM 1156 C CG2 . THR B 2 74  ? -68.033  -9.150  -22.700 1.00 45.45  ? 75  THR L CG2 1 
ATOM 1157 N N   . ILE B 2 75  ? -71.766  -10.468 -25.021 1.00 67.70  ? 76  ILE L N   1 
ATOM 1158 C CA  . ILE B 2 75  ? -73.083  -11.089 -25.080 1.00 62.59  ? 76  ILE L CA  1 
ATOM 1159 C C   . ILE B 2 75  ? -73.004  -12.366 -24.255 1.00 59.82  ? 76  ILE L C   1 
ATOM 1160 O O   . ILE B 2 75  ? -72.256  -13.289 -24.601 1.00 70.02  ? 76  ILE L O   1 
ATOM 1161 C CB  . ILE B 2 75  ? -73.511  -11.377 -26.528 1.00 55.74  ? 76  ILE L CB  1 
ATOM 1162 C CG1 . ILE B 2 75  ? -73.404  -10.107 -27.374 1.00 52.54  ? 76  ILE L CG1 1 
ATOM 1163 C CG2 . ILE B 2 75  ? -74.931  -11.916 -26.574 1.00 54.84  ? 76  ILE L CG2 1 
ATOM 1164 C CD1 . ILE B 2 75  ? -73.789  -10.302 -28.827 1.00 61.23  ? 76  ILE L CD1 1 
ATOM 1165 N N   . SER B 2 76  ? -73.762  -12.414 -23.155 1.00 56.27  ? 77  SER L N   1 
ATOM 1166 C CA  . SER B 2 76  ? -73.614  -13.511 -22.200 1.00 62.62  ? 77  SER L CA  1 
ATOM 1167 C C   . SER B 2 76  ? -73.956  -14.856 -22.833 1.00 69.80  ? 77  SER L C   1 
ATOM 1168 O O   . SER B 2 76  ? -73.226  -15.839 -22.652 1.00 69.71  ? 77  SER L O   1 
ATOM 1169 C CB  . SER B 2 76  ? -74.480  -13.253 -20.967 1.00 58.66  ? 77  SER L CB  1 
ATOM 1170 O OG  . SER B 2 76  ? -75.765  -12.781 -21.331 1.00 68.17  ? 77  SER L OG  1 
ATOM 1171 N N   . ARG B 2 77  ? -75.054  -14.923 -23.583 1.00 52.03  ? 78  ARG L N   1 
ATOM 1172 C CA  . ARG B 2 77  ? -75.378  -16.127 -24.341 1.00 58.06  ? 78  ARG L CA  1 
ATOM 1173 C C   . ARG B 2 77  ? -76.115  -15.717 -25.605 1.00 61.18  ? 78  ARG L C   1 
ATOM 1174 O O   . ARG B 2 77  ? -77.145  -15.038 -25.533 1.00 63.36  ? 78  ARG L O   1 
ATOM 1175 C CB  . ARG B 2 77  ? -76.204  -17.112 -23.509 1.00 57.54  ? 78  ARG L CB  1 
ATOM 1176 C CG  . ARG B 2 77  ? -77.455  -16.541 -22.883 1.00 61.31  ? 78  ARG L CG  1 
ATOM 1177 C CD  . ARG B 2 77  ? -78.427  -17.651 -22.529 1.00 59.28  ? 78  ARG L CD  1 
ATOM 1178 N NE  . ARG B 2 77  ? -79.325  -17.269 -21.446 1.00 73.16  ? 78  ARG L NE  1 
ATOM 1179 C CZ  . ARG B 2 77  ? -79.238  -17.728 -20.205 1.00 82.79  ? 78  ARG L CZ  1 
ATOM 1180 N NH1 . ARG B 2 77  ? -78.303  -18.597 -19.852 1.00 80.28  ? 78  ARG L NH1 1 
ATOM 1181 N NH2 . ARG B 2 77  ? -80.110  -17.306 -19.294 1.00 93.27  ? 78  ARG L NH2 1 
ATOM 1182 N N   . LEU B 2 78  ? -75.585  -16.133 -26.756 1.00 56.06  ? 79  LEU L N   1 
ATOM 1183 C CA  . LEU B 2 78  ? -76.070  -15.645 -28.041 1.00 52.44  ? 79  LEU L CA  1 
ATOM 1184 C C   . LEU B 2 78  ? -77.419  -16.259 -28.392 1.00 54.38  ? 79  LEU L C   1 
ATOM 1185 O O   . LEU B 2 78  ? -77.599  -17.478 -28.316 1.00 62.98  ? 79  LEU L O   1 
ATOM 1186 C CB  . LEU B 2 78  ? -75.053  -15.957 -29.140 1.00 49.44  ? 79  LEU L CB  1 
ATOM 1187 C CG  . LEU B 2 78  ? -73.688  -15.268 -29.052 1.00 53.99  ? 79  LEU L CG  1 
ATOM 1188 C CD1 . LEU B 2 78  ? -72.619  -16.045 -29.811 1.00 40.30  ? 79  LEU L CD1 1 
ATOM 1189 C CD2 . LEU B 2 78  ? -73.789  -13.851 -29.586 1.00 58.24  ? 79  LEU L CD2 1 
ATOM 1190 N N   . GLU B 2 79  ? -78.366  -15.407 -28.776 1.00 57.91  ? 80  GLU L N   1 
ATOM 1191 C CA  . GLU B 2 79  ? -79.630  -15.828 -29.359 1.00 58.43  ? 80  GLU L CA  1 
ATOM 1192 C C   . GLU B 2 79  ? -79.478  -15.982 -30.866 1.00 65.61  ? 80  GLU L C   1 
ATOM 1193 O O   . GLU B 2 79  ? -78.523  -15.469 -31.457 1.00 76.06  ? 80  GLU L O   1 
ATOM 1194 C CB  . GLU B 2 79  ? -80.722  -14.811 -29.033 1.00 69.75  ? 80  GLU L CB  1 
ATOM 1195 C CG  . GLU B 2 79  ? -81.047  -14.703 -27.552 1.00 66.27  ? 80  GLU L CG  1 
ATOM 1196 C CD  . GLU B 2 79  ? -81.734  -15.940 -27.006 1.00 78.74  ? 80  GLU L CD  1 
ATOM 1197 O OE1 . GLU B 2 79  ? -82.390  -16.659 -27.790 1.00 77.79  ? 80  GLU L OE1 1 
ATOM 1198 O OE2 . GLU B 2 79  ? -81.617  -16.196 -25.789 1.00 96.68  ? 80  GLU L OE2 1 
ATOM 1199 N N   . PRO B 2 80  ? -80.388  -16.710 -31.522 1.00 79.24  ? 81  PRO L N   1 
ATOM 1200 C CA  . PRO B 2 80  ? -80.296  -16.824 -32.989 1.00 77.43  ? 81  PRO L CA  1 
ATOM 1201 C C   . PRO B 2 80  ? -80.346  -15.482 -33.700 1.00 62.62  ? 81  PRO L C   1 
ATOM 1202 O O   . PRO B 2 80  ? -79.703  -15.316 -34.744 1.00 67.27  ? 81  PRO L O   1 
ATOM 1203 C CB  . PRO B 2 80  ? -81.503  -17.702 -33.346 1.00 70.43  ? 81  PRO L CB  1 
ATOM 1204 C CG  . PRO B 2 80  ? -81.760  -18.498 -32.111 1.00 75.11  ? 81  PRO L CG  1 
ATOM 1205 C CD  . PRO B 2 80  ? -81.447  -17.572 -30.970 1.00 75.51  ? 81  PRO L CD  1 
ATOM 1206 N N   . GLU B 2 81  ? -81.069  -14.512 -33.147 1.00 68.35  ? 82  GLU L N   1 
ATOM 1207 C CA  . GLU B 2 81  ? -81.174  -13.178 -33.722 1.00 59.93  ? 82  GLU L CA  1 
ATOM 1208 C C   . GLU B 2 81  ? -79.933  -12.320 -33.487 1.00 61.02  ? 82  GLU L C   1 
ATOM 1209 O O   . GLU B 2 81  ? -79.869  -11.202 -34.007 1.00 72.14  ? 82  GLU L O   1 
ATOM 1210 C CB  . GLU B 2 81  ? -82.409  -12.472 -33.152 1.00 63.98  ? 82  GLU L CB  1 
ATOM 1211 C CG  . GLU B 2 81  ? -82.665  -12.782 -31.681 1.00 87.75  ? 82  GLU L CG  1 
ATOM 1212 C CD  . GLU B 2 81  ? -83.750  -11.913 -31.071 1.00 111.26 ? 82  GLU L CD  1 
ATOM 1213 O OE1 . GLU B 2 81  ? -84.388  -11.141 -31.820 1.00 113.95 ? 82  GLU L OE1 1 
ATOM 1214 O OE2 . GLU B 2 81  ? -83.961  -11.998 -29.841 1.00 90.74  ? 82  GLU L OE2 1 
ATOM 1215 N N   . ASP B 2 82  ? -78.954  -12.801 -32.723 1.00 66.02  ? 83  ASP L N   1 
ATOM 1216 C CA  . ASP B 2 82  ? -77.785  -12.005 -32.365 1.00 63.37  ? 83  ASP L CA  1 
ATOM 1217 C C   . ASP B 2 82  ? -76.645  -12.112 -33.370 1.00 52.04  ? 83  ASP L C   1 
ATOM 1218 O O   . ASP B 2 82  ? -75.622  -11.440 -33.195 1.00 47.67  ? 83  ASP L O   1 
ATOM 1219 C CB  . ASP B 2 82  ? -77.266  -12.415 -30.980 1.00 64.28  ? 83  ASP L CB  1 
ATOM 1220 C CG  . ASP B 2 82  ? -78.221  -12.047 -29.864 1.00 66.15  ? 83  ASP L CG  1 
ATOM 1221 O OD1 . ASP B 2 82  ? -79.120  -11.211 -30.095 1.00 63.85  ? 83  ASP L OD1 1 
ATOM 1222 O OD2 . ASP B 2 82  ? -78.064  -12.588 -28.747 1.00 71.52  ? 83  ASP L OD2 1 
ATOM 1223 N N   . PHE B 2 83  ? -76.784  -12.936 -34.408 1.00 65.99  ? 84  PHE L N   1 
ATOM 1224 C CA  . PHE B 2 83  ? -75.692  -13.174 -35.355 1.00 71.28  ? 84  PHE L CA  1 
ATOM 1225 C C   . PHE B 2 83  ? -75.758  -12.150 -36.491 1.00 60.80  ? 84  PHE L C   1 
ATOM 1226 O O   . PHE B 2 83  ? -76.116  -12.440 -37.634 1.00 68.25  ? 84  PHE L O   1 
ATOM 1227 C CB  . PHE B 2 83  ? -75.740  -14.608 -35.862 1.00 57.19  ? 84  PHE L CB  1 
ATOM 1228 C CG  . PHE B 2 83  ? -75.479  -15.629 -34.792 1.00 62.35  ? 84  PHE L CG  1 
ATOM 1229 C CD1 . PHE B 2 83  ? -74.186  -16.037 -34.509 1.00 67.59  ? 84  PHE L CD1 1 
ATOM 1230 C CD2 . PHE B 2 83  ? -76.524  -16.174 -34.062 1.00 61.11  ? 84  PHE L CD2 1 
ATOM 1231 C CE1 . PHE B 2 83  ? -73.937  -16.970 -33.519 1.00 44.86  ? 84  PHE L CE1 1 
ATOM 1232 C CE2 . PHE B 2 83  ? -76.280  -17.110 -33.073 1.00 57.84  ? 84  PHE L CE2 1 
ATOM 1233 C CZ  . PHE B 2 83  ? -74.984  -17.510 -32.805 1.00 41.45  ? 84  PHE L CZ  1 
ATOM 1234 N N   . VAL B 2 84  ? -75.392  -10.919 -36.139 1.00 60.52  ? 85  VAL L N   1 
ATOM 1235 C CA  . VAL B 2 84  ? -75.459  -9.765  -37.029 1.00 35.30  ? 85  VAL L CA  1 
ATOM 1236 C C   . VAL B 2 84  ? -74.158  -8.988  -36.871 1.00 49.92  ? 85  VAL L C   1 
ATOM 1237 O O   . VAL B 2 84  ? -73.198  -9.495  -36.280 1.00 55.02  ? 85  VAL L O   1 
ATOM 1238 C CB  . VAL B 2 84  ? -76.694  -8.898  -36.727 1.00 46.60  ? 85  VAL L CB  1 
ATOM 1239 C CG1 . VAL B 2 84  ? -77.967  -9.651  -37.098 1.00 41.87  ? 85  VAL L CG1 1 
ATOM 1240 C CG2 . VAL B 2 84  ? -76.715  -8.494  -35.262 1.00 57.85  ? 85  VAL L CG2 1 
ATOM 1241 N N   . VAL B 2 85  ? -74.081  -7.777  -37.434 1.00 54.69  ? 86  VAL L N   1 
ATOM 1242 C CA  . VAL B 2 85  ? -72.837  -7.019  -37.333 1.00 58.88  ? 86  VAL L CA  1 
ATOM 1243 C C   . VAL B 2 85  ? -72.927  -6.062  -36.149 1.00 50.34  ? 86  VAL L C   1 
ATOM 1244 O O   . VAL B 2 85  ? -74.017  -5.658  -35.731 1.00 56.27  ? 86  VAL L O   1 
ATOM 1245 C CB  . VAL B 2 85  ? -72.517  -6.285  -38.655 1.00 50.94  ? 86  VAL L CB  1 
ATOM 1246 C CG1 . VAL B 2 85  ? -73.454  -5.123  -38.869 1.00 52.98  ? 86  VAL L CG1 1 
ATOM 1247 C CG2 . VAL B 2 85  ? -71.065  -5.824  -38.684 1.00 55.88  ? 86  VAL L CG2 1 
ATOM 1248 N N   . TYR B 2 86  ? -71.772  -5.714  -35.580 1.00 43.48  ? 87  TYR L N   1 
ATOM 1249 C CA  . TYR B 2 86  ? -71.695  -4.846  -34.410 1.00 54.21  ? 87  TYR L CA  1 
ATOM 1250 C C   . TYR B 2 86  ? -70.630  -3.782  -34.634 1.00 50.79  ? 87  TYR L C   1 
ATOM 1251 O O   . TYR B 2 86  ? -69.497  -4.103  -35.003 1.00 57.06  ? 87  TYR L O   1 
ATOM 1252 C CB  . TYR B 2 86  ? -71.389  -5.663  -33.144 1.00 60.12  ? 87  TYR L CB  1 
ATOM 1253 C CG  . TYR B 2 86  ? -72.496  -6.628  -32.778 1.00 46.06  ? 87  TYR L CG  1 
ATOM 1254 C CD1 . TYR B 2 86  ? -73.620  -6.192  -32.088 1.00 49.00  ? 87  TYR L CD1 1 
ATOM 1255 C CD2 . TYR B 2 86  ? -72.437  -7.964  -33.157 1.00 48.63  ? 87  TYR L CD2 1 
ATOM 1256 C CE1 . TYR B 2 86  ? -74.642  -7.064  -31.759 1.00 53.25  ? 87  TYR L CE1 1 
ATOM 1257 C CE2 . TYR B 2 86  ? -73.459  -8.844  -32.840 1.00 53.31  ? 87  TYR L CE2 1 
ATOM 1258 C CZ  . TYR B 2 86  ? -74.560  -8.386  -32.138 1.00 63.98  ? 87  TYR L CZ  1 
ATOM 1259 O OH  . TYR B 2 86  ? -75.583  -9.246  -31.809 1.00 60.35  ? 87  TYR L OH  1 
ATOM 1260 N N   . HIS B 2 87  ? -70.991  -2.522  -34.395 1.00 55.11  ? 88  HIS L N   1 
ATOM 1261 C CA  . HIS B 2 87  ? -70.097  -1.392  -34.609 1.00 57.54  ? 88  HIS L CA  1 
ATOM 1262 C C   . HIS B 2 87  ? -69.803  -0.681  -33.294 1.00 58.57  ? 88  HIS L C   1 
ATOM 1263 O O   . HIS B 2 87  ? -70.659  -0.607  -32.408 1.00 60.41  ? 88  HIS L O   1 
ATOM 1264 C CB  . HIS B 2 87  ? -70.693  -0.382  -35.602 1.00 60.19  ? 88  HIS L CB  1 
ATOM 1265 C CG  . HIS B 2 87  ? -71.223  -1.002  -36.857 1.00 68.78  ? 88  HIS L CG  1 
ATOM 1266 N ND1 . HIS B 2 87  ? -70.418  -1.303  -37.935 1.00 59.40  ? 88  HIS L ND1 1 
ATOM 1267 C CD2 . HIS B 2 87  ? -72.480  -1.357  -37.215 1.00 64.11  ? 88  HIS L CD2 1 
ATOM 1268 C CE1 . HIS B 2 87  ? -71.155  -1.831  -38.897 1.00 69.79  ? 88  HIS L CE1 1 
ATOM 1269 N NE2 . HIS B 2 87  ? -72.409  -1.874  -38.486 1.00 55.53  ? 88  HIS L NE2 1 
ATOM 1270 N N   . CYS B 2 88  ? -68.585  -0.150  -33.176 1.00 60.25  ? 89  CYS L N   1 
ATOM 1271 C CA  . CYS B 2 88  ? -68.202  0.689   -32.046 1.00 65.22  ? 89  CYS L CA  1 
ATOM 1272 C C   . CYS B 2 88  ? -67.920  2.097   -32.551 1.00 57.81  ? 89  CYS L C   1 
ATOM 1273 O O   . CYS B 2 88  ? -67.238  2.275   -33.564 1.00 69.14  ? 89  CYS L O   1 
ATOM 1274 C CB  . CYS B 2 88  ? -66.983  0.129   -31.291 1.00 53.45  ? 89  CYS L CB  1 
ATOM 1275 S SG  . CYS B 2 88  ? -65.356  0.347   -32.076 1.00 86.29  ? 89  CYS L SG  1 
ATOM 1276 N N   . GLN B 2 89  ? -68.464  3.087   -31.852 1.00 66.31  ? 90  GLN L N   1 
ATOM 1277 C CA  . GLN B 2 89  ? -68.293  4.493   -32.183 1.00 61.49  ? 90  GLN L CA  1 
ATOM 1278 C C   . GLN B 2 89  ? -67.706  5.232   -30.991 1.00 61.09  ? 90  GLN L C   1 
ATOM 1279 O O   . GLN B 2 89  ? -68.081  4.975   -29.844 1.00 54.68  ? 90  GLN L O   1 
ATOM 1280 C CB  . GLN B 2 89  ? -69.626  5.137   -32.568 1.00 59.40  ? 90  GLN L CB  1 
ATOM 1281 C CG  . GLN B 2 89  ? -69.554  6.646   -32.726 1.00 58.84  ? 90  GLN L CG  1 
ATOM 1282 C CD  . GLN B 2 89  ? -70.882  7.322   -32.468 1.00 60.87  ? 90  GLN L CD  1 
ATOM 1283 O OE1 . GLN B 2 89  ? -71.921  6.668   -32.403 1.00 56.00  ? 90  GLN L OE1 1 
ATOM 1284 N NE2 . GLN B 2 89  ? -70.854  8.641   -32.314 1.00 62.20  ? 90  GLN L NE2 1 
ATOM 1285 N N   . GLN B 2 90  ? -66.788  6.152   -31.257 1.00 52.91  ? 91  GLN L N   1 
ATOM 1286 C CA  . GLN B 2 90  ? -66.286  7.054   -30.233 1.00 57.26  ? 91  GLN L CA  1 
ATOM 1287 C C   . GLN B 2 90  ? -66.867  8.445   -30.458 1.00 65.20  ? 91  GLN L C   1 
ATOM 1288 O O   . GLN B 2 90  ? -66.970  8.911   -31.598 1.00 58.87  ? 91  GLN L O   1 
ATOM 1289 C CB  . GLN B 2 90  ? -64.753  7.090   -30.225 1.00 44.75  ? 91  GLN L CB  1 
ATOM 1290 C CG  . GLN B 2 90  ? -64.123  7.858   -31.373 1.00 71.00  ? 91  GLN L CG  1 
ATOM 1291 C CD  . GLN B 2 90  ? -63.864  9.311   -31.038 1.00 62.37  ? 91  GLN L CD  1 
ATOM 1292 O OE1 . GLN B 2 90  ? -63.978  9.725   -29.884 1.00 70.10  ? 91  GLN L OE1 1 
ATOM 1293 N NE2 . GLN B 2 90  ? -63.519  10.097  -32.050 1.00 69.29  ? 91  GLN L NE2 1 
ATOM 1294 N N   . TYR B 2 91  ? -67.283  9.091   -29.367 1.00 58.78  ? 92  TYR L N   1 
ATOM 1295 C CA  . TYR B 2 91  ? -67.809  10.448  -29.448 1.00 54.10  ? 92  TYR L CA  1 
ATOM 1296 C C   . TYR B 2 91  ? -67.262  11.321  -28.328 1.00 53.42  ? 92  TYR L C   1 
ATOM 1297 O O   . TYR B 2 91  ? -67.934  12.257  -27.879 1.00 61.74  ? 92  TYR L O   1 
ATOM 1298 C CB  . TYR B 2 91  ? -69.342  10.460  -29.436 1.00 53.90  ? 92  TYR L CB  1 
ATOM 1299 C CG  . TYR B 2 91  ? -69.990  9.659   -28.326 1.00 67.42  ? 92  TYR L CG  1 
ATOM 1300 C CD1 . TYR B 2 91  ? -70.165  8.285   -28.443 1.00 53.83  ? 92  TYR L CD1 1 
ATOM 1301 C CD2 . TYR B 2 91  ? -70.442  10.280  -27.166 1.00 60.84  ? 92  TYR L CD2 1 
ATOM 1302 C CE1 . TYR B 2 91  ? -70.760  7.552   -27.433 1.00 56.00  ? 92  TYR L CE1 1 
ATOM 1303 C CE2 . TYR B 2 91  ? -71.039  9.556   -26.153 1.00 55.69  ? 92  TYR L CE2 1 
ATOM 1304 C CZ  . TYR B 2 91  ? -71.195  8.192   -26.290 1.00 62.89  ? 92  TYR L CZ  1 
ATOM 1305 O OH  . TYR B 2 91  ? -71.792  7.467   -25.283 1.00 62.56  ? 92  TYR L OH  1 
ATOM 1306 N N   . GLY B 2 92  ? -66.053  11.028  -27.862 1.00 52.03  ? 93  GLY L N   1 
ATOM 1307 C CA  . GLY B 2 92  ? -65.358  11.877  -26.921 1.00 65.24  ? 93  GLY L CA  1 
ATOM 1308 C C   . GLY B 2 92  ? -64.483  12.930  -27.553 1.00 58.60  ? 93  GLY L C   1 
ATOM 1309 O O   . GLY B 2 92  ? -63.797  13.670  -26.840 1.00 61.51  ? 93  GLY L O   1 
ATOM 1310 N N   . SER B 2 93  ? -64.481  13.017  -28.880 1.00 68.19  ? 94  SER L N   1 
ATOM 1311 C CA  . SER B 2 93  ? -63.650  13.973  -29.598 1.00 67.13  ? 94  SER L CA  1 
ATOM 1312 C C   . SER B 2 93  ? -64.247  14.181  -30.981 1.00 64.53  ? 94  SER L C   1 
ATOM 1313 O O   . SER B 2 93  ? -65.099  13.411  -31.434 1.00 64.59  ? 94  SER L O   1 
ATOM 1314 C CB  . SER B 2 93  ? -62.200  13.494  -29.693 1.00 66.64  ? 94  SER L CB  1 
ATOM 1315 O OG  . SER B 2 93  ? -62.081  12.434  -30.626 1.00 100.08 ? 94  SER L OG  1 
ATOM 1316 N N   . SER B 2 94  ? -63.791  15.243  -31.649 1.00 63.84  ? 95  SER L N   1 
ATOM 1317 C CA  . SER B 2 94  ? -64.269  15.524  -32.990 1.00 67.49  ? 95  SER L CA  1 
ATOM 1318 C C   . SER B 2 94  ? -63.167  15.270  -34.012 1.00 73.06  ? 95  SER L C   1 
ATOM 1319 O O   . SER B 2 94  ? -62.009  15.631  -33.775 1.00 79.52  ? 95  SER L O   1 
ATOM 1320 C CB  . SER B 2 94  ? -64.752  16.975  -33.111 1.00 60.79  ? 95  SER L CB  1 
ATOM 1321 O OG  . SER B 2 94  ? -65.430  17.192  -34.337 1.00 71.70  ? 95  SER L OG  1 
ATOM 1322 N N   . PRO B 2 95  ? -63.488  14.643  -35.151 1.00 62.30  ? 96  PRO L N   1 
ATOM 1323 C CA  . PRO B 2 95  ? -64.802  14.125  -35.556 1.00 69.83  ? 96  PRO L CA  1 
ATOM 1324 C C   . PRO B 2 95  ? -65.136  12.799  -34.884 1.00 66.67  ? 96  PRO L C   1 
ATOM 1325 O O   . PRO B 2 95  ? -64.250  12.105  -34.392 1.00 61.27  ? 96  PRO L O   1 
ATOM 1326 C CB  . PRO B 2 95  ? -64.645  13.969  -37.072 1.00 52.41  ? 96  PRO L CB  1 
ATOM 1327 C CG  . PRO B 2 95  ? -63.203  13.574  -37.229 1.00 59.80  ? 96  PRO L CG  1 
ATOM 1328 C CD  . PRO B 2 95  ? -62.461  14.369  -36.175 1.00 52.39  ? 96  PRO L CD  1 
ATOM 1329 N N   . ARG B 2 96  ? -66.409  12.421  -34.845 1.00 62.08  ? 97  ARG L N   1 
ATOM 1330 C CA  . ARG B 2 96  ? -66.792  11.128  -34.301 1.00 63.47  ? 97  ARG L CA  1 
ATOM 1331 C C   . ARG B 2 96  ? -66.437  10.049  -35.311 1.00 58.05  ? 97  ARG L C   1 
ATOM 1332 O O   . ARG B 2 96  ? -66.750  10.178  -36.497 1.00 78.26  ? 97  ARG L O   1 
ATOM 1333 C CB  . ARG B 2 96  ? -68.287  11.097  -33.981 1.00 65.24  ? 97  ARG L CB  1 
ATOM 1334 C CG  . ARG B 2 96  ? -68.844  12.448  -33.581 1.00 56.67  ? 97  ARG L CG  1 
ATOM 1335 C CD  . ARG B 2 96  ? -68.285  12.935  -32.254 1.00 49.35  ? 97  ARG L CD  1 
ATOM 1336 N NE  . ARG B 2 96  ? -69.137  13.967  -31.679 1.00 55.27  ? 97  ARG L NE  1 
ATOM 1337 C CZ  . ARG B 2 96  ? -68.983  14.483  -30.470 1.00 41.72  ? 97  ARG L CZ  1 
ATOM 1338 N NH1 . ARG B 2 96  ? -67.983  14.118  -29.687 1.00 66.33  ? 97  ARG L NH1 1 
ATOM 1339 N NH2 . ARG B 2 96  ? -69.852  15.392  -30.038 1.00 49.61  ? 97  ARG L NH2 1 
ATOM 1340 N N   . THR B 2 97  ? -65.776  8.991   -34.852 1.00 66.92  ? 98  THR L N   1 
ATOM 1341 C CA  . THR B 2 97  ? -65.299  7.940   -35.739 1.00 66.96  ? 98  THR L CA  1 
ATOM 1342 C C   . THR B 2 97  ? -65.855  6.590   -35.308 1.00 67.48  ? 98  THR L C   1 
ATOM 1343 O O   . THR B 2 97  ? -65.898  6.276   -34.114 1.00 61.58  ? 98  THR L O   1 
ATOM 1344 C CB  . THR B 2 97  ? -63.769  7.888   -35.763 1.00 62.52  ? 98  THR L CB  1 
ATOM 1345 O OG1 . THR B 2 97  ? -63.261  7.943   -34.425 1.00 53.97  ? 98  THR L OG1 1 
ATOM 1346 C CG2 . THR B 2 97  ? -63.218  9.067   -36.545 1.00 68.26  ? 98  THR L CG2 1 
ATOM 1347 N N   . PHE B 2 98  ? -66.276  5.797   -36.292 1.00 64.58  ? 99  PHE L N   1 
ATOM 1348 C CA  . PHE B 2 98  ? -66.792  4.457   -36.074 1.00 54.08  ? 99  PHE L CA  1 
ATOM 1349 C C   . PHE B 2 98  ? -65.677  3.427   -36.243 1.00 65.57  ? 99  PHE L C   1 
ATOM 1350 O O   . PHE B 2 98  ? -64.527  3.752   -36.552 1.00 63.48  ? 99  PHE L O   1 
ATOM 1351 C CB  . PHE B 2 98  ? -67.941  4.161   -37.039 1.00 57.62  ? 99  PHE L CB  1 
ATOM 1352 C CG  . PHE B 2 98  ? -69.193  4.931   -36.748 1.00 64.89  ? 99  PHE L CG  1 
ATOM 1353 C CD1 . PHE B 2 98  ? -69.376  6.202   -37.265 1.00 58.20  ? 99  PHE L CD1 1 
ATOM 1354 C CD2 . PHE B 2 98  ? -70.191  4.381   -35.963 1.00 64.44  ? 99  PHE L CD2 1 
ATOM 1355 C CE1 . PHE B 2 98  ? -70.531  6.911   -37.001 1.00 71.63  ? 99  PHE L CE1 1 
ATOM 1356 C CE2 . PHE B 2 98  ? -71.349  5.086   -35.694 1.00 69.91  ? 99  PHE L CE2 1 
ATOM 1357 C CZ  . PHE B 2 98  ? -71.520  6.353   -36.213 1.00 71.93  ? 99  PHE L CZ  1 
ATOM 1358 N N   . GLY B 2 99  ? -66.030  2.160   -36.031 1.00 63.29  ? 100 GLY L N   1 
ATOM 1359 C CA  . GLY B 2 99  ? -65.142  1.056   -36.310 1.00 59.25  ? 100 GLY L CA  1 
ATOM 1360 C C   . GLY B 2 99  ? -65.529  0.337   -37.597 1.00 80.76  ? 100 GLY L C   1 
ATOM 1361 O O   . GLY B 2 99  ? -66.564  0.602   -38.205 1.00 71.78  ? 100 GLY L O   1 
ATOM 1362 N N   . GLN B 2 100 ? -64.665  -0.597  -38.003 1.00 74.46  ? 101 GLN L N   1 
ATOM 1363 C CA  . GLN B 2 100 ? -64.914  -1.342  -39.232 1.00 64.45  ? 101 GLN L CA  1 
ATOM 1364 C C   . GLN B 2 100 ? -66.095  -2.294  -39.084 1.00 69.47  ? 101 GLN L C   1 
ATOM 1365 O O   . GLN B 2 100 ? -66.759  -2.614  -40.076 1.00 60.54  ? 101 GLN L O   1 
ATOM 1366 C CB  . GLN B 2 100 ? -63.662  -2.116  -39.643 1.00 66.18  ? 101 GLN L CB  1 
ATOM 1367 C CG  . GLN B 2 100 ? -63.182  -3.120  -38.608 1.00 82.57  ? 101 GLN L CG  1 
ATOM 1368 C CD  . GLN B 2 100 ? -62.021  -2.600  -37.788 1.00 97.44  ? 101 GLN L CD  1 
ATOM 1369 O OE1 . GLN B 2 100 ? -62.057  -1.476  -37.287 1.00 102.22 ? 101 GLN L OE1 1 
ATOM 1370 N NE2 . GLN B 2 100 ? -60.980  -3.415  -37.651 1.00 99.83  ? 101 GLN L NE2 1 
ATOM 1371 N N   . GLY B 2 101 ? -66.371  -2.747  -37.867 1.00 79.98  ? 102 GLY L N   1 
ATOM 1372 C CA  . GLY B 2 101 ? -67.445  -3.681  -37.610 1.00 72.03  ? 102 GLY L CA  1 
ATOM 1373 C C   . GLY B 2 101 ? -66.937  -5.100  -37.408 1.00 76.62  ? 102 GLY L C   1 
ATOM 1374 O O   . GLY B 2 101 ? -65.864  -5.488  -37.876 1.00 89.01  ? 102 GLY L O   1 
ATOM 1375 N N   . THR B 2 102 ? -67.733  -5.888  -36.687 1.00 69.09  ? 103 THR L N   1 
ATOM 1376 C CA  . THR B 2 102 ? -67.422  -7.284  -36.411 1.00 61.15  ? 103 THR L CA  1 
ATOM 1377 C C   . THR B 2 102 ? -68.644  -8.129  -36.735 1.00 64.81  ? 103 THR L C   1 
ATOM 1378 O O   . THR B 2 102 ? -69.764  -7.774  -36.355 1.00 61.71  ? 103 THR L O   1 
ATOM 1379 C CB  . THR B 2 102 ? -67.006  -7.488  -34.947 1.00 78.26  ? 103 THR L CB  1 
ATOM 1380 O OG1 . THR B 2 102 ? -65.782  -6.786  -34.689 1.00 85.14  ? 103 THR L OG1 1 
ATOM 1381 C CG2 . THR B 2 102 ? -66.806  -8.967  -34.641 1.00 77.12  ? 103 THR L CG2 1 
ATOM 1382 N N   . LYS B 2 103 ? -68.430  -9.235  -37.441 1.00 72.02  ? 104 LYS L N   1 
ATOM 1383 C CA  . LYS B 2 103 ? -69.498  -10.162 -37.789 1.00 69.85  ? 104 LYS L CA  1 
ATOM 1384 C C   . LYS B 2 103 ? -69.490  -11.337 -36.820 1.00 73.69  ? 104 LYS L C   1 
ATOM 1385 O O   . LYS B 2 103 ? -68.439  -11.936 -36.570 1.00 71.00  ? 104 LYS L O   1 
ATOM 1386 C CB  . LYS B 2 103 ? -69.345  -10.659 -39.228 1.00 64.88  ? 104 LYS L CB  1 
ATOM 1387 C CG  . LYS B 2 103 ? -70.252  -11.829 -39.587 1.00 58.85  ? 104 LYS L CG  1 
ATOM 1388 C CD  . LYS B 2 103 ? -71.714  -11.417 -39.616 1.00 66.28  ? 104 LYS L CD  1 
ATOM 1389 C CE  . LYS B 2 103 ? -72.616  -12.610 -39.888 1.00 60.75  ? 104 LYS L CE  1 
ATOM 1390 N NZ  . LYS B 2 103 ? -74.056  -12.225 -39.901 1.00 57.88  ? 104 LYS L NZ  1 
ATOM 1391 N N   . VAL B 2 104 ? -70.657  -11.653 -36.266 1.00 60.06  ? 105 VAL L N   1 
ATOM 1392 C CA  . VAL B 2 104 ? -70.842  -12.830 -35.425 1.00 70.26  ? 105 VAL L CA  1 
ATOM 1393 C C   . VAL B 2 104 ? -71.643  -13.840 -36.234 1.00 68.41  ? 105 VAL L C   1 
ATOM 1394 O O   . VAL B 2 104 ? -72.763  -13.546 -36.672 1.00 59.73  ? 105 VAL L O   1 
ATOM 1395 C CB  . VAL B 2 104 ? -71.544  -12.484 -34.102 1.00 65.74  ? 105 VAL L CB  1 
ATOM 1396 C CG1 . VAL B 2 104 ? -71.796  -13.741 -33.289 1.00 55.41  ? 105 VAL L CG1 1 
ATOM 1397 C CG2 . VAL B 2 104 ? -70.709  -11.495 -33.302 1.00 51.68  ? 105 VAL L CG2 1 
ATOM 1398 N N   . GLU B 2 105 ? -71.067  -15.024 -36.443 1.00 68.57  ? 106 GLU L N   1 
ATOM 1399 C CA  . GLU B 2 105 ? -71.662  -16.040 -37.299 1.00 85.75  ? 106 GLU L CA  1 
ATOM 1400 C C   . GLU B 2 105 ? -71.812  -17.351 -36.543 1.00 71.80  ? 106 GLU L C   1 
ATOM 1401 O O   . GLU B 2 105 ? -71.030  -17.665 -35.640 1.00 57.42  ? 106 GLU L O   1 
ATOM 1402 C CB  . GLU B 2 105 ? -70.828  -16.274 -38.571 1.00 77.26  ? 106 GLU L CB  1 
ATOM 1403 C CG  . GLU B 2 105 ? -69.492  -16.960 -38.323 1.00 75.80  ? 106 GLU L CG  1 
ATOM 1404 C CD  . GLU B 2 105 ? -69.127  -17.953 -39.411 1.00 98.92  ? 106 GLU L CD  1 
ATOM 1405 O OE1 . GLU B 2 105 ? -69.777  -17.941 -40.478 1.00 118.21 ? 106 GLU L OE1 1 
ATOM 1406 O OE2 . GLU B 2 105 ? -68.186  -18.748 -39.198 1.00 102.33 ? 106 GLU L OE2 1 
ATOM 1407 N N   . ILE B 2 106 ? -72.828  -18.118 -36.939 1.00 53.74  ? 107 ILE L N   1 
ATOM 1408 C CA  . ILE B 2 106 ? -73.110  -19.399 -36.304 1.00 58.97  ? 107 ILE L CA  1 
ATOM 1409 C C   . ILE B 2 106 ? -72.020  -20.397 -36.666 1.00 61.26  ? 107 ILE L C   1 
ATOM 1410 O O   . ILE B 2 106 ? -71.704  -20.591 -37.846 1.00 75.11  ? 107 ILE L O   1 
ATOM 1411 C CB  . ILE B 2 106 ? -74.491  -19.913 -36.734 1.00 59.49  ? 107 ILE L CB  1 
ATOM 1412 C CG1 . ILE B 2 106 ? -75.590  -18.989 -36.203 1.00 55.21  ? 107 ILE L CG1 1 
ATOM 1413 C CG2 . ILE B 2 106 ? -74.699  -21.350 -36.269 1.00 66.28  ? 107 ILE L CG2 1 
ATOM 1414 C CD1 . ILE B 2 106 ? -76.991  -19.493 -36.461 1.00 59.64  ? 107 ILE L CD1 1 
ATOM 1415 N N   . ARG B 2 107 ? -71.462  -21.060 -35.647 1.00 64.71  ? 108 ARG L N   1 
ATOM 1416 C CA  . ARG B 2 107 ? -70.464  -22.133 -35.898 1.00 75.30  ? 108 ARG L CA  1 
ATOM 1417 C C   . ARG B 2 107 ? -71.220  -23.455 -35.988 1.00 78.13  ? 108 ARG L C   1 
ATOM 1418 O O   . ARG B 2 107 ? -72.186  -23.625 -35.230 1.00 65.37  ? 108 ARG L O   1 
ATOM 1419 C CB  . ARG B 2 107 ? -69.401  -22.203 -34.803 1.00 66.05  ? 108 ARG L CB  1 
ATOM 1420 C CG  . ARG B 2 107 ? -68.204  -23.072 -35.158 1.00 61.41  ? 108 ARG L CG  1 
ATOM 1421 C CD  . ARG B 2 107 ? -67.148  -23.067 -34.071 1.00 87.08  ? 108 ARG L CD  1 
ATOM 1422 N NE  . ARG B 2 107 ? -67.646  -22.541 -32.810 1.00 99.73  ? 108 ARG L NE  1 
ATOM 1423 C CZ  . ARG B 2 107 ? -68.031  -23.288 -31.782 1.00 89.83  ? 108 ARG L CZ  1 
ATOM 1424 N NH1 . ARG B 2 107 ? -68.490  -24.508 -31.989 1.00 86.12  ? 108 ARG L NH1 1 
ATOM 1425 N NH2 . ARG B 2 107 ? -67.962  -22.808 -30.553 1.00 71.54  ? 108 ARG L NH2 1 
ATOM 1426 N N   . ARG B 2 108 ? -70.796  -24.348 -36.881 1.00 80.84  ? 109 ARG L N   1 
ATOM 1427 C CA  . ARG B 2 108 ? -71.563  -25.597 -37.112 1.00 75.01  ? 109 ARG L CA  1 
ATOM 1428 C C   . ARG B 2 108 ? -70.614  -26.733 -37.483 1.00 83.65  ? 109 ARG L C   1 
ATOM 1429 O O   . ARG B 2 108 ? -69.389  -26.522 -37.442 1.00 76.21  ? 109 ARG L O   1 
ATOM 1430 C CB  . ARG B 2 108 ? -72.565  -25.379 -38.246 1.00 80.19  ? 109 ARG L CB  1 
ATOM 1431 C CG  . ARG B 2 108 ? -73.854  -26.176 -38.110 1.00 92.98  ? 109 ARG L CG  1 
ATOM 1432 C CD  . ARG B 2 108 ? -74.634  -26.191 -39.409 1.00 89.85  ? 109 ARG L CD  1 
ATOM 1433 N NE  . ARG B 2 108 ? -74.494  -27.436 -40.150 1.00 85.02  ? 109 ARG L NE  1 
ATOM 1434 C CZ  . ARG B 2 108 ? -73.378  -27.834 -40.746 1.00 92.17  ? 109 ARG L CZ  1 
ATOM 1435 N NH1 . ARG B 2 108 ? -72.515  -26.942 -41.196 1.00 84.26  ? 109 ARG L NH1 1 
ATOM 1436 N NH2 . ARG B 2 108 ? -73.127  -29.123 -40.891 1.00 103.63 ? 109 ARG L NH2 1 
ATOM 1437 N N   . THR B 2 109 ? -71.175  -27.893 -37.821 1.00 86.58  ? 110 THR L N   1 
ATOM 1438 C CA  . THR B 2 109 ? -70.341  -29.039 -38.261 1.00 88.44  ? 110 THR L CA  1 
ATOM 1439 C C   . THR B 2 109 ? -69.701  -28.660 -39.597 1.00 111.56 ? 110 THR L C   1 
ATOM 1440 O O   . THR B 2 109 ? -70.279  -27.815 -40.299 1.00 104.87 ? 110 THR L O   1 
ATOM 1441 C CB  . THR B 2 109 ? -71.163  -30.331 -38.275 1.00 86.38  ? 110 THR L CB  1 
ATOM 1442 O OG1 . THR B 2 109 ? -72.284  -30.148 -37.411 1.00 87.93  ? 110 THR L OG1 1 
ATOM 1443 C CG2 . THR B 2 109 ? -70.366  -31.536 -37.828 1.00 91.89  ? 110 THR L CG2 1 
ATOM 1444 N N   . VAL B 2 110 ? -68.584  -29.287 -39.957 1.00 118.57 ? 111 VAL L N   1 
ATOM 1445 C CA  . VAL B 2 110 ? -67.828  -28.893 -41.140 1.00 105.97 ? 111 VAL L CA  1 
ATOM 1446 C C   . VAL B 2 110 ? -68.533  -29.350 -42.412 1.00 96.90  ? 111 VAL L C   1 
ATOM 1447 O O   . VAL B 2 110 ? -68.418  -30.512 -42.819 1.00 115.59 ? 111 VAL L O   1 
ATOM 1448 C CB  . VAL B 2 110 ? -66.390  -29.445 -41.070 1.00 100.02 ? 111 VAL L CB  1 
ATOM 1449 C CG1 . VAL B 2 110 ? -65.638  -29.183 -42.365 1.00 82.72  ? 111 VAL L CG1 1 
ATOM 1450 C CG2 . VAL B 2 110 ? -65.650  -28.840 -39.884 1.00 107.05 ? 111 VAL L CG2 1 
ATOM 1451 N N   . ALA B 2 111 ? -69.288  -28.434 -43.024 1.00 113.22 ? 112 ALA L N   1 
ATOM 1452 C CA  . ALA B 2 111 ? -69.730  -28.513 -44.415 1.00 130.02 ? 112 ALA L CA  1 
ATOM 1453 C C   . ALA B 2 111 ? -70.669  -29.671 -44.742 1.00 139.13 ? 112 ALA L C   1 
ATOM 1454 O O   . ALA B 2 111 ? -70.833  -30.608 -43.954 1.00 148.77 ? 112 ALA L O   1 
ATOM 1455 C CB  . ALA B 2 111 ? -68.512  -28.577 -45.339 1.00 121.16 ? 112 ALA L CB  1 
ATOM 1456 N N   . ALA B 2 112 ? -71.312  -29.584 -45.911 1.00 134.78 ? 113 ALA L N   1 
ATOM 1457 C CA  . ALA B 2 112 ? -72.114  -30.640 -46.518 1.00 137.63 ? 113 ALA L CA  1 
ATOM 1458 C C   . ALA B 2 112 ? -72.322  -30.318 -47.995 1.00 133.82 ? 113 ALA L C   1 
ATOM 1459 O O   . ALA B 2 112 ? -73.457  -30.067 -48.420 1.00 141.70 ? 113 ALA L O   1 
ATOM 1460 C CB  . ALA B 2 112 ? -73.458  -30.790 -45.803 1.00 122.47 ? 113 ALA L CB  1 
ATOM 1461 N N   . PRO B 2 113 ? -71.261  -30.312 -48.806 1.00 133.32 ? 114 PRO L N   1 
ATOM 1462 C CA  . PRO B 2 113 ? -71.363  -29.764 -50.170 1.00 145.16 ? 114 PRO L CA  1 
ATOM 1463 C C   . PRO B 2 113 ? -72.193  -30.655 -51.084 1.00 146.42 ? 114 PRO L C   1 
ATOM 1464 O O   . PRO B 2 113 ? -71.888  -31.836 -51.268 1.00 163.12 ? 114 PRO L O   1 
ATOM 1465 C CB  . PRO B 2 113 ? -69.901  -29.682 -50.634 1.00 144.25 ? 114 PRO L CB  1 
ATOM 1466 C CG  . PRO B 2 113 ? -69.070  -29.946 -49.400 1.00 143.49 ? 114 PRO L CG  1 
ATOM 1467 C CD  . PRO B 2 113 ? -69.909  -30.815 -48.528 1.00 130.52 ? 114 PRO L CD  1 
ATOM 1468 N N   . SER B 2 114 ? -73.238  -30.075 -51.667 1.00 125.92 ? 115 SER L N   1 
ATOM 1469 C CA  . SER B 2 114 ? -74.097  -30.788 -52.606 1.00 112.53 ? 115 SER L CA  1 
ATOM 1470 C C   . SER B 2 114 ? -73.847  -30.320 -54.035 1.00 121.97 ? 115 SER L C   1 
ATOM 1471 O O   . SER B 2 114 ? -74.484  -29.380 -54.510 1.00 125.06 ? 115 SER L O   1 
ATOM 1472 C CB  . SER B 2 114 ? -75.571  -30.596 -52.243 1.00 95.72  ? 115 SER L CB  1 
ATOM 1473 N N   . PRO B 2 119 ? -66.715  -26.349 -68.714 1.00 167.74 ? 120 PRO L N   1 
ATOM 1474 C CA  . PRO B 2 119 ? -66.813  -26.064 -70.148 1.00 143.20 ? 120 PRO L CA  1 
ATOM 1475 C C   . PRO B 2 119 ? -67.307  -24.629 -70.379 1.00 133.87 ? 120 PRO L C   1 
ATOM 1476 O O   . PRO B 2 119 ? -67.708  -23.984 -69.432 1.00 139.66 ? 120 PRO L O   1 
ATOM 1477 C CB  . PRO B 2 119 ? -67.854  -27.051 -70.697 1.00 152.63 ? 120 PRO L CB  1 
ATOM 1478 C CG  . PRO B 2 119 ? -68.044  -28.056 -69.590 1.00 165.28 ? 120 PRO L CG  1 
ATOM 1479 C CD  . PRO B 2 119 ? -67.794  -27.262 -68.328 1.00 167.53 ? 120 PRO L CD  1 
ATOM 1480 N N   . PRO B 2 120 ? -67.294  -24.120 -71.629 1.00 134.56 ? 121 PRO L N   1 
ATOM 1481 C CA  . PRO B 2 120 ? -67.835  -22.783 -71.888 1.00 136.45 ? 121 PRO L CA  1 
ATOM 1482 C C   . PRO B 2 120 ? -69.214  -22.849 -72.565 1.00 136.42 ? 121 PRO L C   1 
ATOM 1483 O O   . PRO B 2 120 ? -69.519  -23.879 -73.145 1.00 128.06 ? 121 PRO L O   1 
ATOM 1484 C CB  . PRO B 2 120 ? -66.787  -22.189 -72.837 1.00 117.29 ? 121 PRO L CB  1 
ATOM 1485 N N   . SER B 2 121 ? -70.003  -21.771 -72.486 1.00 133.37 ? 122 SER L N   1 
ATOM 1486 C CA  . SER B 2 121 ? -71.358  -21.717 -73.095 1.00 130.01 ? 122 SER L CA  1 
ATOM 1487 C C   . SER B 2 121 ? -71.263  -21.406 -74.590 1.00 129.44 ? 122 SER L C   1 
ATOM 1488 O O   . SER B 2 121 ? -70.205  -20.937 -75.043 1.00 116.86 ? 122 SER L O   1 
ATOM 1489 C CB  . SER B 2 121 ? -72.230  -20.711 -72.395 1.00 120.29 ? 122 SER L CB  1 
ATOM 1490 N N   . ASP B 2 122 ? -72.352  -21.641 -75.315 1.00 129.38 ? 123 ASP L N   1 
ATOM 1491 C CA  . ASP B 2 122 ? -72.353  -21.386 -76.775 1.00 137.02 ? 123 ASP L CA  1 
ATOM 1492 C C   . ASP B 2 122 ? -72.730  -19.926 -77.027 1.00 145.62 ? 123 ASP L C   1 
ATOM 1493 O O   . ASP B 2 122 ? -71.843  -19.150 -77.415 1.00 152.77 ? 123 ASP L O   1 
ATOM 1494 C CB  . ASP B 2 122 ? -73.310  -22.337 -77.493 1.00 134.84 ? 123 ASP L CB  1 
ATOM 1495 N N   . GLU B 2 123 ? -73.997  -19.573 -76.804 1.00 138.64 ? 124 GLU L N   1 
ATOM 1496 C CA  . GLU B 2 123 ? -74.470  -18.193 -77.092 1.00 145.11 ? 124 GLU L CA  1 
ATOM 1497 C C   . GLU B 2 123 ? -73.411  -17.167 -76.667 1.00 152.60 ? 124 GLU L C   1 
ATOM 1498 O O   . GLU B 2 123 ? -73.063  -16.321 -77.494 1.00 144.91 ? 124 GLU L O   1 
ATOM 1499 C CB  . GLU B 2 123 ? -75.808  -17.955 -76.391 1.00 138.50 ? 124 GLU L CB  1 
ATOM 1500 C CG  . GLU B 2 123 ? -76.541  -19.234 -76.039 1.00 120.94 ? 124 GLU L CG  1 
ATOM 1501 C CD  . GLU B 2 123 ? -78.013  -19.031 -75.730 1.00 139.40 ? 124 GLU L CD  1 
ATOM 1502 O OE1 . GLU B 2 123 ? -78.461  -17.867 -75.738 1.00 139.71 ? 124 GLU L OE1 1 
ATOM 1503 O OE2 . GLU B 2 123 ? -78.708  -20.035 -75.484 1.00 144.83 ? 124 GLU L OE2 1 
ATOM 1504 N N   . GLN B 2 124 ? -72.934  -17.237 -75.423 1.00 160.35 ? 125 GLN L N   1 
ATOM 1505 C CA  . GLN B 2 124 ? -71.926  -16.273 -74.908 1.00 152.47 ? 125 GLN L CA  1 
ATOM 1506 C C   . GLN B 2 124 ? -70.687  -16.284 -75.807 1.00 143.27 ? 125 GLN L C   1 
ATOM 1507 O O   . GLN B 2 124 ? -70.253  -15.202 -76.220 1.00 135.00 ? 125 GLN L O   1 
ATOM 1508 C CB  . GLN B 2 124 ? -71.548  -16.646 -73.476 1.00 145.23 ? 125 GLN L CB  1 
ATOM 1509 C CG  . GLN B 2 124 ? -71.124  -15.468 -72.621 1.00 134.40 ? 125 GLN L CG  1 
ATOM 1510 C CD  . GLN B 2 124 ? -70.691  -15.921 -71.251 1.00 129.54 ? 125 GLN L CD  1 
ATOM 1511 O OE1 . GLN B 2 124 ? -69.940  -15.238 -70.562 1.00 129.83 ? 125 GLN L OE1 1 
ATOM 1512 N NE2 . GLN B 2 124 ? -71.165  -17.088 -70.847 1.00 131.03 ? 125 GLN L NE2 1 
ATOM 1513 N N   . LEU B 2 125 ? -70.125  -17.468 -76.071 1.00 141.07 ? 126 LEU L N   1 
ATOM 1514 C CA  . LEU B 2 125 ? -68.946  -17.567 -76.969 1.00 135.20 ? 126 LEU L CA  1 
ATOM 1515 C C   . LEU B 2 125 ? -69.342  -16.961 -78.315 1.00 137.14 ? 126 LEU L C   1 
ATOM 1516 O O   . LEU B 2 125 ? -68.578  -16.134 -78.837 1.00 131.58 ? 126 LEU L O   1 
ATOM 1517 C CB  . LEU B 2 125 ? -68.550  -19.038 -77.118 1.00 118.22 ? 126 LEU L CB  1 
ATOM 1518 C CG  . LEU B 2 125 ? -67.058  -19.312 -77.289 1.00 119.82 ? 126 LEU L CG  1 
ATOM 1519 C CD1 . LEU B 2 125 ? -66.242  -18.045 -77.089 1.00 118.11 ? 126 LEU L CD1 1 
ATOM 1520 C CD2 . LEU B 2 125 ? -66.601  -20.399 -76.331 1.00 127.68 ? 126 LEU L CD2 1 
ATOM 1521 N N   . LYS B 2 126 ? -70.499  -17.361 -78.842 1.00 134.03 ? 127 LYS L N   1 
ATOM 1522 C CA  . LYS B 2 126 ? -70.986  -16.768 -80.111 1.00 133.60 ? 127 LYS L CA  1 
ATOM 1523 C C   . LYS B 2 126 ? -71.055  -15.255 -79.913 1.00 138.99 ? 127 LYS L C   1 
ATOM 1524 O O   . LYS B 2 126 ? -70.686  -14.518 -80.844 1.00 133.04 ? 127 LYS L O   1 
ATOM 1525 C CB  . LYS B 2 126 ? -72.348  -17.362 -80.479 1.00 135.58 ? 127 LYS L CB  1 
ATOM 1526 C CG  . LYS B 2 126 ? -73.432  -16.360 -80.849 1.00 139.36 ? 127 LYS L CG  1 
ATOM 1527 C CD  . LYS B 2 126 ? -74.639  -16.998 -81.497 1.00 134.06 ? 127 LYS L CD  1 
ATOM 1528 C CE  . LYS B 2 126 ? -75.243  -18.107 -80.665 1.00 128.39 ? 127 LYS L CE  1 
ATOM 1529 N NZ  . LYS B 2 126 ? -76.591  -17.742 -80.168 1.00 110.38 ? 127 LYS L NZ  1 
ATOM 1530 N N   . SER B 2 127 ? -71.493  -14.819 -78.732 1.00 145.20 ? 128 SER L N   1 
ATOM 1531 C CA  . SER B 2 127 ? -71.583  -13.394 -78.448 1.00 142.62 ? 128 SER L CA  1 
ATOM 1532 C C   . SER B 2 127 ? -70.230  -12.782 -78.108 1.00 140.99 ? 128 SER L C   1 
ATOM 1533 O O   . SER B 2 127 ? -70.171  -11.604 -77.738 1.00 134.61 ? 128 SER L O   1 
ATOM 1534 C CB  . SER B 2 127 ? -72.571  -13.143 -77.304 1.00 133.06 ? 128 SER L CB  1 
ATOM 1535 O OG  . SER B 2 127 ? -73.857  -13.651 -77.616 1.00 124.08 ? 128 SER L OG  1 
ATOM 1536 N N   . GLY B 2 128 ? -69.150  -13.552 -78.220 1.00 134.25 ? 129 GLY L N   1 
ATOM 1537 C CA  . GLY B 2 128 ? -67.827  -13.055 -77.901 1.00 128.76 ? 129 GLY L CA  1 
ATOM 1538 C C   . GLY B 2 128 ? -67.271  -13.619 -76.610 1.00 147.63 ? 129 GLY L C   1 
ATOM 1539 O O   . GLY B 2 128 ? -66.853  -14.781 -76.561 1.00 139.98 ? 129 GLY L O   1 
ATOM 1540 N N   . THR B 2 129 ? -67.269  -12.804 -75.557 1.00 155.36 ? 130 THR L N   1 
ATOM 1541 C CA  . THR B 2 129 ? -66.679  -13.200 -74.287 1.00 151.91 ? 130 THR L CA  1 
ATOM 1542 C C   . THR B 2 129 ? -67.424  -14.390 -73.686 1.00 146.65 ? 130 THR L C   1 
ATOM 1543 O O   . THR B 2 129 ? -68.574  -14.678 -74.025 1.00 140.33 ? 130 THR L O   1 
ATOM 1544 C CB  . THR B 2 129 ? -66.687  -12.029 -73.303 1.00 147.18 ? 130 THR L CB  1 
ATOM 1545 O OG1 . THR B 2 129 ? -66.105  -12.441 -72.061 1.00 150.56 ? 130 THR L OG1 1 
ATOM 1546 C CG2 . THR B 2 129 ? -68.112  -11.547 -73.053 1.00 126.00 ? 130 THR L CG2 1 
ATOM 1547 N N   . ALA B 2 130 ? -66.738  -15.092 -72.786 1.00 145.04 ? 131 ALA L N   1 
ATOM 1548 C CA  . ALA B 2 130 ? -67.282  -16.262 -72.116 1.00 145.36 ? 131 ALA L CA  1 
ATOM 1549 C C   . ALA B 2 130 ? -66.889  -16.227 -70.645 1.00 156.39 ? 131 ALA L C   1 
ATOM 1550 O O   . ALA B 2 130 ? -65.899  -15.597 -70.257 1.00 161.09 ? 131 ALA L O   1 
ATOM 1551 C CB  . ALA B 2 130 ? -66.798  -17.566 -72.767 1.00 134.18 ? 131 ALA L CB  1 
ATOM 1552 N N   . SER B 2 131 ? -67.689  -16.909 -69.825 1.00 158.72 ? 132 SER L N   1 
ATOM 1553 C CA  . SER B 2 131 ? -67.469  -16.968 -68.384 1.00 150.54 ? 132 SER L CA  1 
ATOM 1554 C C   . SER B 2 131 ? -67.784  -18.369 -67.883 1.00 139.87 ? 132 SER L C   1 
ATOM 1555 O O   . SER B 2 131 ? -68.919  -18.838 -68.012 1.00 125.18 ? 132 SER L O   1 
ATOM 1556 C CB  . SER B 2 131 ? -68.323  -15.934 -67.648 1.00 143.80 ? 132 SER L CB  1 
ATOM 1557 O OG  . SER B 2 131 ? -67.781  -14.635 -67.796 1.00 142.53 ? 132 SER L OG  1 
ATOM 1558 N N   . VAL B 2 132 ? -66.784  -19.017 -67.295 1.00 139.97 ? 133 VAL L N   1 
ATOM 1559 C CA  . VAL B 2 132 ? -66.916  -20.366 -66.753 1.00 143.54 ? 133 VAL L CA  1 
ATOM 1560 C C   . VAL B 2 132 ? -67.132  -20.269 -65.250 1.00 148.51 ? 133 VAL L C   1 
ATOM 1561 O O   . VAL B 2 132 ? -66.407  -19.545 -64.556 1.00 146.44 ? 133 VAL L O   1 
ATOM 1562 C CB  . VAL B 2 132 ? -65.680  -21.221 -67.078 1.00 134.33 ? 133 VAL L CB  1 
ATOM 1563 N N   . VAL B 2 133 ? -68.119  -21.002 -64.742 1.00 133.02 ? 134 VAL L N   1 
ATOM 1564 C CA  . VAL B 2 133 ? -68.523  -20.926 -63.344 1.00 115.84 ? 134 VAL L CA  1 
ATOM 1565 C C   . VAL B 2 133 ? -68.003  -22.148 -62.601 1.00 144.44 ? 134 VAL L C   1 
ATOM 1566 O O   . VAL B 2 133 ? -68.014  -23.264 -63.133 1.00 147.35 ? 134 VAL L O   1 
ATOM 1567 C CB  . VAL B 2 133 ? -70.054  -20.815 -63.209 1.00 117.94 ? 134 VAL L CB  1 
ATOM 1568 N N   . CYS B 2 134 ? -67.540  -21.930 -61.370 1.00 171.22 ? 135 CYS L N   1 
ATOM 1569 C CA  . CYS B 2 134 ? -67.129  -22.987 -60.445 1.00 159.88 ? 135 CYS L CA  1 
ATOM 1570 C C   . CYS B 2 134 ? -67.959  -22.815 -59.177 1.00 138.71 ? 135 CYS L C   1 
ATOM 1571 O O   . CYS B 2 134 ? -67.572  -22.082 -58.263 1.00 136.88 ? 135 CYS L O   1 
ATOM 1572 C CB  . CYS B 2 134 ? -65.632  -22.926 -60.150 1.00 149.93 ? 135 CYS L CB  1 
ATOM 1573 S SG  . CYS B 2 134 ? -64.960  -24.441 -59.439 1.00 149.63 ? 135 CYS L SG  1 
ATOM 1574 N N   . LEU B 2 135 ? -69.094  -23.501 -59.118 1.00 140.36 ? 136 LEU L N   1 
ATOM 1575 C CA  . LEU B 2 135 ? -70.094  -23.279 -58.086 1.00 139.94 ? 136 LEU L CA  1 
ATOM 1576 C C   . LEU B 2 135 ? -70.095  -24.410 -57.063 1.00 138.72 ? 136 LEU L C   1 
ATOM 1577 O O   . LEU B 2 135 ? -69.634  -25.523 -57.329 1.00 151.78 ? 136 LEU L O   1 
ATOM 1578 C CB  . LEU B 2 135 ? -71.480  -23.130 -58.718 1.00 138.45 ? 136 LEU L CB  1 
ATOM 1579 C CG  . LEU B 2 135 ? -71.991  -21.691 -58.786 1.00 149.22 ? 136 LEU L CG  1 
ATOM 1580 C CD1 . LEU B 2 135 ? -72.182  -21.134 -57.384 1.00 153.42 ? 136 LEU L CD1 1 
ATOM 1581 C CD2 . LEU B 2 135 ? -71.046  -20.814 -59.599 1.00 139.53 ? 136 LEU L CD2 1 
ATOM 1582 N N   . LEU B 2 136 ? -70.621  -24.101 -55.875 1.00 141.83 ? 137 LEU L N   1 
ATOM 1583 C CA  . LEU B 2 136 ? -70.667  -25.028 -54.749 1.00 130.74 ? 137 LEU L CA  1 
ATOM 1584 C C   . LEU B 2 136 ? -72.008  -24.858 -54.042 1.00 125.23 ? 137 LEU L C   1 
ATOM 1585 O O   . LEU B 2 136 ? -72.874  -24.100 -54.491 1.00 138.61 ? 137 LEU L O   1 
ATOM 1586 C CB  . LEU B 2 136 ? -69.489  -24.792 -53.793 1.00 92.73  ? 137 LEU L CB  1 
ATOM 1587 C CG  . LEU B 2 136 ? -68.104  -24.669 -54.440 1.00 118.34 ? 137 LEU L CG  1 
ATOM 1588 C CD1 . LEU B 2 136 ? -67.604  -23.232 -54.384 1.00 128.83 ? 137 LEU L CD1 1 
ATOM 1589 C CD2 . LEU B 2 136 ? -67.098  -25.615 -53.805 1.00 123.37 ? 137 LEU L CD2 1 
ATOM 1590 N N   . ASN B 2 137 ? -72.214  -25.549 -52.919 1.00 127.86 ? 138 ASN L N   1 
ATOM 1591 C CA  . ASN B 2 137 ? -73.495  -25.300 -52.199 1.00 140.48 ? 138 ASN L CA  1 
ATOM 1592 C C   . ASN B 2 137 ? -73.353  -25.524 -50.688 1.00 151.87 ? 138 ASN L C   1 
ATOM 1593 O O   . ASN B 2 137 ? -72.209  -25.492 -50.192 1.00 145.12 ? 138 ASN L O   1 
ATOM 1594 C CB  . ASN B 2 137 ? -74.662  -26.098 -52.791 1.00 126.29 ? 138 ASN L CB  1 
ATOM 1595 C CG  . ASN B 2 137 ? -75.955  -25.310 -52.803 1.00 122.56 ? 138 ASN L CG  1 
ATOM 1596 O OD1 . ASN B 2 137 ? -75.936  -24.082 -52.827 1.00 118.13 ? 138 ASN L OD1 1 
ATOM 1597 N ND2 . ASN B 2 137 ? -77.080  -26.005 -52.777 1.00 119.49 ? 138 ASN L ND2 1 
ATOM 1598 N N   . ASN B 2 138 ? -74.476  -25.747 -49.993 1.00 147.28 ? 139 ASN L N   1 
ATOM 1599 C CA  . ASN B 2 138 ? -74.476  -25.866 -48.509 1.00 124.72 ? 139 ASN L CA  1 
ATOM 1600 C C   . ASN B 2 138 ? -73.098  -26.275 -47.984 1.00 127.59 ? 139 ASN L C   1 
ATOM 1601 O O   . ASN B 2 138 ? -72.772  -27.459 -48.060 1.00 143.15 ? 139 ASN L O   1 
ATOM 1602 C CB  . ASN B 2 138 ? -75.601  -26.791 -48.044 1.00 113.81 ? 139 ASN L CB  1 
ATOM 1603 C CG  . ASN B 2 138 ? -76.935  -26.407 -48.645 1.00 115.56 ? 139 ASN L CG  1 
ATOM 1604 O OD1 . ASN B 2 138 ? -77.076  -26.346 -49.863 1.00 122.51 ? 139 ASN L OD1 1 
ATOM 1605 N ND2 . ASN B 2 138 ? -77.917  -26.136 -47.801 1.00 96.04  ? 139 ASN L ND2 1 
ATOM 1606 N N   . PHE B 2 139 ? -72.328  -25.321 -47.466 1.00 132.81 ? 140 PHE L N   1 
ATOM 1607 C CA  . PHE B 2 139 ? -71.019  -25.638 -46.838 1.00 133.28 ? 140 PHE L CA  1 
ATOM 1608 C C   . PHE B 2 139 ? -70.791  -24.606 -45.729 1.00 131.72 ? 140 PHE L C   1 
ATOM 1609 O O   . PHE B 2 139 ? -71.312  -23.485 -45.860 1.00 139.67 ? 140 PHE L O   1 
ATOM 1610 C CB  . PHE B 2 139 ? -69.889  -25.635 -47.868 1.00 120.73 ? 140 PHE L CB  1 
ATOM 1611 C CG  . PHE B 2 139 ? -69.148  -24.328 -47.987 1.00 142.93 ? 140 PHE L CG  1 
ATOM 1612 C CD1 . PHE B 2 139 ? -69.639  -23.309 -48.783 1.00 137.15 ? 140 PHE L CD1 1 
ATOM 1613 C CD2 . PHE B 2 139 ? -67.964  -24.112 -47.304 1.00 141.66 ? 140 PHE L CD2 1 
ATOM 1614 C CE1 . PHE B 2 139 ? -68.970  -22.101 -48.891 1.00 141.36 ? 140 PHE L CE1 1 
ATOM 1615 C CE2 . PHE B 2 139 ? -67.292  -22.906 -47.423 1.00 141.11 ? 140 PHE L CE2 1 
ATOM 1616 C CZ  . PHE B 2 139 ? -67.796  -21.900 -48.208 1.00 135.79 ? 140 PHE L CZ  1 
ATOM 1617 N N   . TYR B 2 140 ? -70.077  -24.968 -44.665 1.00 103.13 ? 141 TYR L N   1 
ATOM 1618 C CA  . TYR B 2 140 ? -69.898  -24.021 -43.571 1.00 122.91 ? 141 TYR L CA  1 
ATOM 1619 C C   . TYR B 2 140 ? -68.536  -23.316 -43.568 1.00 128.77 ? 141 TYR L C   1 
ATOM 1620 O O   . TYR B 2 140 ? -68.501  -22.084 -43.679 1.00 147.39 ? 141 TYR L O   1 
ATOM 1621 C CB  . TYR B 2 140 ? -70.142  -24.685 -42.212 1.00 113.55 ? 141 TYR L CB  1 
ATOM 1622 C CG  . TYR B 2 140 ? -69.673  -23.797 -41.090 1.00 93.66  ? 141 TYR L CG  1 
ATOM 1623 C CD1 . TYR B 2 140 ? -70.243  -22.548 -40.883 1.00 85.36  ? 141 TYR L CD1 1 
ATOM 1624 C CD2 . TYR B 2 140 ? -68.615  -24.180 -40.277 1.00 92.22  ? 141 TYR L CD2 1 
ATOM 1625 C CE1 . TYR B 2 140 ? -69.793  -21.720 -39.877 1.00 99.85  ? 141 TYR L CE1 1 
ATOM 1626 C CE2 . TYR B 2 140 ? -68.160  -23.361 -39.266 1.00 98.44  ? 141 TYR L CE2 1 
ATOM 1627 C CZ  . TYR B 2 140 ? -68.752  -22.132 -39.069 1.00 95.71  ? 141 TYR L CZ  1 
ATOM 1628 O OH  . TYR B 2 140 ? -68.298  -21.313 -38.063 1.00 91.37  ? 141 TYR L OH  1 
ATOM 1629 N N   . PRO B 2 141 ? -67.404  -24.023 -43.449 1.00 111.44 ? 142 PRO L N   1 
ATOM 1630 C CA  . PRO B 2 141 ? -66.138  -23.329 -43.139 1.00 111.56 ? 142 PRO L CA  1 
ATOM 1631 C C   . PRO B 2 141 ? -65.695  -22.456 -44.301 1.00 143.71 ? 142 PRO L C   1 
ATOM 1632 O O   . PRO B 2 141 ? -65.386  -22.964 -45.380 1.00 160.60 ? 142 PRO L O   1 
ATOM 1633 C CB  . PRO B 2 141 ? -65.155  -24.479 -42.894 1.00 92.61  ? 142 PRO L CB  1 
ATOM 1634 C CG  . PRO B 2 141 ? -66.010  -25.642 -42.549 1.00 99.83  ? 142 PRO L CG  1 
ATOM 1635 C CD  . PRO B 2 141 ? -67.207  -25.483 -43.443 1.00 89.97  ? 142 PRO L CD  1 
ATOM 1636 N N   . ARG B 2 142 ? -65.566  -21.149 -44.051 1.00 137.75 ? 143 ARG L N   1 
ATOM 1637 C CA  . ARG B 2 142 ? -65.541  -20.146 -45.119 1.00 125.18 ? 143 ARG L CA  1 
ATOM 1638 C C   . ARG B 2 142 ? -64.252  -20.260 -45.929 1.00 132.97 ? 143 ARG L C   1 
ATOM 1639 O O   . ARG B 2 142 ? -63.309  -19.478 -45.787 1.00 121.52 ? 143 ARG L O   1 
ATOM 1640 C CB  . ARG B 2 142 ? -65.689  -18.741 -44.543 1.00 125.47 ? 143 ARG L CB  1 
ATOM 1641 C CG  . ARG B 2 142 ? -66.723  -18.596 -43.440 1.00 148.15 ? 143 ARG L CG  1 
ATOM 1642 C CD  . ARG B 2 142 ? -67.722  -17.503 -43.790 1.00 148.34 ? 143 ARG L CD  1 
ATOM 1643 N NE  . ARG B 2 142 ? -68.348  -16.924 -42.607 1.00 127.19 ? 143 ARG L NE  1 
ATOM 1644 C CZ  . ARG B 2 142 ? -68.788  -15.675 -42.530 1.00 121.69 ? 143 ARG L CZ  1 
ATOM 1645 N NH1 . ARG B 2 142 ? -68.673  -14.838 -43.548 1.00 140.43 ? 143 ARG L NH1 1 
ATOM 1646 N NH2 . ARG B 2 142 ? -69.354  -15.255 -41.403 1.00 123.98 ? 143 ARG L NH2 1 
ATOM 1647 N N   . GLU B 2 143 ? -64.223  -21.270 -46.801 1.00 150.63 ? 144 GLU L N   1 
ATOM 1648 C CA  . GLU B 2 143 ? -63.177  -21.391 -47.815 1.00 154.07 ? 144 GLU L CA  1 
ATOM 1649 C C   . GLU B 2 143 ? -63.746  -22.264 -48.936 1.00 164.27 ? 144 GLU L C   1 
ATOM 1650 O O   . GLU B 2 143 ? -63.801  -23.489 -48.796 1.00 174.00 ? 144 GLU L O   1 
ATOM 1651 C CB  . GLU B 2 143 ? -61.902  -21.983 -47.234 1.00 149.33 ? 144 GLU L CB  1 
ATOM 1652 C CG  . GLU B 2 143 ? -60.755  -22.085 -48.229 1.00 160.81 ? 144 GLU L CG  1 
ATOM 1653 C CD  . GLU B 2 143 ? -60.715  -20.918 -49.199 1.00 157.03 ? 144 GLU L CD  1 
ATOM 1654 O OE1 . GLU B 2 143 ? -60.561  -19.766 -48.741 1.00 163.09 ? 144 GLU L OE1 1 
ATOM 1655 O OE2 . GLU B 2 143 ? -60.841  -21.154 -50.419 1.00 145.62 ? 144 GLU L OE2 1 
ATOM 1656 N N   . ALA B 2 144 ? -64.170  -21.628 -50.028 1.00 172.53 ? 145 ALA L N   1 
ATOM 1657 C CA  . ALA B 2 144 ? -64.785  -22.325 -51.153 1.00 165.68 ? 145 ALA L CA  1 
ATOM 1658 C C   . ALA B 2 144 ? -64.175  -21.826 -52.454 1.00 168.98 ? 145 ALA L C   1 
ATOM 1659 O O   . ALA B 2 144 ? -64.189  -20.619 -52.721 1.00 175.54 ? 145 ALA L O   1 
ATOM 1660 C CB  . ALA B 2 144 ? -66.302  -22.124 -51.167 1.00 147.23 ? 145 ALA L CB  1 
ATOM 1661 N N   . LYS B 2 145 ? -63.644  -22.759 -53.251 1.00 162.53 ? 146 LYS L N   1 
ATOM 1662 C CA  . LYS B 2 145 ? -63.077  -22.512 -54.576 1.00 159.48 ? 146 LYS L CA  1 
ATOM 1663 C C   . LYS B 2 145 ? -61.786  -21.704 -54.466 1.00 170.26 ? 146 LYS L C   1 
ATOM 1664 O O   . LYS B 2 145 ? -61.768  -20.633 -53.852 1.00 186.48 ? 146 LYS L O   1 
ATOM 1665 C CB  . LYS B 2 145 ? -64.095  -21.807 -55.481 1.00 153.43 ? 146 LYS L CB  1 
ATOM 1666 C CG  . LYS B 2 145 ? -63.878  -22.036 -56.971 1.00 156.00 ? 146 LYS L CG  1 
ATOM 1667 C CD  . LYS B 2 145 ? -62.750  -21.184 -57.523 1.00 165.30 ? 146 LYS L CD  1 
ATOM 1668 C CE  . LYS B 2 145 ? -62.402  -21.583 -58.941 1.00 156.87 ? 146 LYS L CE  1 
ATOM 1669 N NZ  . LYS B 2 145 ? -61.106  -20.986 -59.346 1.00 164.92 ? 146 LYS L NZ  1 
ATOM 1670 N N   . VAL B 2 146 ? -60.700  -22.200 -55.060 1.00 167.47 ? 147 VAL L N   1 
ATOM 1671 C CA  . VAL B 2 146 ? -59.401  -21.548 -54.911 1.00 175.66 ? 147 VAL L CA  1 
ATOM 1672 C C   . VAL B 2 146 ? -58.790  -21.170 -56.257 1.00 174.96 ? 147 VAL L C   1 
ATOM 1673 O O   . VAL B 2 146 ? -58.588  -19.985 -56.543 1.00 163.86 ? 147 VAL L O   1 
ATOM 1674 C CB  . VAL B 2 146 ? -58.431  -22.438 -54.112 1.00 169.82 ? 147 VAL L CB  1 
ATOM 1675 C CG1 . VAL B 2 146 ? -57.139  -21.688 -53.818 1.00 159.30 ? 147 VAL L CG1 1 
ATOM 1676 C CG2 . VAL B 2 146 ? -59.079  -22.898 -52.821 1.00 157.78 ? 147 VAL L CG2 1 
ATOM 1677 N N   . GLN B 2 147 ? -58.495  -22.164 -57.095 1.00 180.28 ? 148 GLN L N   1 
ATOM 1678 C CA  . GLN B 2 147 ? -57.660  -21.953 -58.271 1.00 166.28 ? 148 GLN L CA  1 
ATOM 1679 C C   . GLN B 2 147 ? -58.342  -22.473 -59.530 1.00 163.41 ? 148 GLN L C   1 
ATOM 1680 O O   . GLN B 2 147 ? -59.196  -23.362 -59.484 1.00 159.89 ? 148 GLN L O   1 
ATOM 1681 C CB  . GLN B 2 147 ? -56.291  -22.632 -58.112 1.00 143.35 ? 148 GLN L CB  1 
ATOM 1682 N N   . TRP B 2 148 ? -57.942  -21.899 -60.662 1.00 169.68 ? 149 TRP L N   1 
ATOM 1683 C CA  . TRP B 2 148 ? -58.398  -22.297 -61.986 1.00 170.80 ? 149 TRP L CA  1 
ATOM 1684 C C   . TRP B 2 148 ? -57.264  -23.019 -62.706 1.00 170.86 ? 149 TRP L C   1 
ATOM 1685 O O   . TRP B 2 148 ? -56.117  -23.030 -62.253 1.00 172.84 ? 149 TRP L O   1 
ATOM 1686 C CB  . TRP B 2 148 ? -58.855  -21.076 -62.795 1.00 157.74 ? 149 TRP L CB  1 
ATOM 1687 C CG  . TRP B 2 148 ? -60.316  -20.748 -62.648 1.00 147.73 ? 149 TRP L CG  1 
ATOM 1688 C CD1 . TRP B 2 148 ? -60.845  -19.658 -62.020 1.00 132.72 ? 149 TRP L CD1 1 
ATOM 1689 C CD2 . TRP B 2 148 ? -61.431  -21.510 -63.135 1.00 147.05 ? 149 TRP L CD2 1 
ATOM 1690 N NE1 . TRP B 2 148 ? -62.216  -19.695 -62.080 1.00 134.49 ? 149 TRP L NE1 1 
ATOM 1691 C CE2 . TRP B 2 148 ? -62.602  -20.820 -62.760 1.00 134.70 ? 149 TRP L CE2 1 
ATOM 1692 C CE3 . TRP B 2 148 ? -61.553  -22.705 -63.851 1.00 146.39 ? 149 TRP L CE3 1 
ATOM 1693 C CZ2 . TRP B 2 148 ? -63.877  -21.285 -63.078 1.00 126.82 ? 149 TRP L CZ2 1 
ATOM 1694 C CZ3 . TRP B 2 148 ? -62.822  -23.165 -64.164 1.00 135.34 ? 149 TRP L CZ3 1 
ATOM 1695 C CH2 . TRP B 2 148 ? -63.966  -22.456 -63.778 1.00 126.22 ? 149 TRP L CH2 1 
ATOM 1696 N N   . LYS B 2 149 ? -57.591  -23.629 -63.847 1.00 172.35 ? 150 LYS L N   1 
ATOM 1697 C CA  . LYS B 2 149 ? -56.583  -24.354 -64.623 1.00 174.76 ? 150 LYS L CA  1 
ATOM 1698 C C   . LYS B 2 149 ? -56.961  -24.267 -66.099 1.00 181.14 ? 150 LYS L C   1 
ATOM 1699 O O   . LYS B 2 149 ? -57.894  -24.941 -66.546 1.00 181.01 ? 150 LYS L O   1 
ATOM 1700 C CB  . LYS B 2 149 ? -56.466  -25.799 -64.159 1.00 166.06 ? 150 LYS L CB  1 
ATOM 1701 N N   . VAL B 2 150 ? -56.231  -23.441 -66.843 1.00 181.23 ? 151 VAL L N   1 
ATOM 1702 C CA  . VAL B 2 150 ? -56.406  -23.304 -68.283 1.00 173.95 ? 151 VAL L CA  1 
ATOM 1703 C C   . VAL B 2 150 ? -55.253  -24.057 -68.939 1.00 184.74 ? 151 VAL L C   1 
ATOM 1704 O O   . VAL B 2 150 ? -54.128  -23.552 -69.011 1.00 187.68 ? 151 VAL L O   1 
ATOM 1705 C CB  . VAL B 2 150 ? -56.446  -21.836 -68.714 1.00 166.41 ? 151 VAL L CB  1 
ATOM 1706 N N   . ASP B 2 151 ? -55.537  -25.267 -69.423 1.00 188.80 ? 152 ASP L N   1 
ATOM 1707 C CA  . ASP B 2 151 ? -54.532  -26.146 -70.024 1.00 193.58 ? 152 ASP L CA  1 
ATOM 1708 C C   . ASP B 2 151 ? -53.349  -26.354 -69.079 1.00 197.57 ? 152 ASP L C   1 
ATOM 1709 O O   . ASP B 2 151 ? -52.184  -26.185 -69.449 1.00 200.80 ? 152 ASP L O   1 
ATOM 1710 C CB  . ASP B 2 151 ? -54.067  -25.605 -71.379 1.00 188.98 ? 152 ASP L CB  1 
ATOM 1711 C CG  . ASP B 2 151 ? -55.026  -25.947 -72.504 1.00 171.60 ? 152 ASP L CG  1 
ATOM 1712 O OD1 . ASP B 2 151 ? -55.572  -27.070 -72.503 1.00 164.90 ? 152 ASP L OD1 1 
ATOM 1713 O OD2 . ASP B 2 151 ? -55.233  -25.092 -73.391 1.00 156.97 ? 152 ASP L OD2 1 
ATOM 1714 N N   . ASN B 2 152 ? -53.668  -26.726 -67.836 1.00 198.12 ? 153 ASN L N   1 
ATOM 1715 C CA  . ASN B 2 152 ? -52.672  -26.976 -66.791 1.00 198.66 ? 153 ASN L CA  1 
ATOM 1716 C C   . ASN B 2 152 ? -51.820  -25.733 -66.529 1.00 197.45 ? 153 ASN L C   1 
ATOM 1717 O O   . ASN B 2 152 ? -50.589  -25.772 -66.574 1.00 202.22 ? 153 ASN L O   1 
ATOM 1718 C CB  . ASN B 2 152 ? -51.797  -28.184 -67.141 1.00 199.71 ? 153 ASN L CB  1 
ATOM 1719 C CG  . ASN B 2 152 ? -51.065  -28.745 -65.936 1.00 191.14 ? 153 ASN L CG  1 
ATOM 1720 O OD1 . ASN B 2 152 ? -51.495  -28.568 -64.796 1.00 189.55 ? 153 ASN L OD1 1 
ATOM 1721 N ND2 . ASN B 2 152 ? -49.952  -29.427 -66.184 1.00 180.53 ? 153 ASN L ND2 1 
ATOM 1722 N N   . ALA B 2 153 ? -52.494  -24.618 -66.251 1.00 187.91 ? 154 ALA L N   1 
ATOM 1723 C CA  . ALA B 2 153 ? -51.820  -23.363 -65.951 1.00 178.95 ? 154 ALA L CA  1 
ATOM 1724 C C   . ALA B 2 153 ? -52.731  -22.498 -65.092 1.00 179.66 ? 154 ALA L C   1 
ATOM 1725 O O   . ALA B 2 153 ? -53.939  -22.429 -65.333 1.00 181.25 ? 154 ALA L O   1 
ATOM 1726 C CB  . ALA B 2 153 ? -51.432  -22.613 -67.231 1.00 175.59 ? 154 ALA L CB  1 
ATOM 1727 N N   . LEU B 2 154 ? -52.144  -21.841 -64.096 1.00 173.69 ? 155 LEU L N   1 
ATOM 1728 C CA  . LEU B 2 154 ? -52.887  -20.974 -63.194 1.00 159.24 ? 155 LEU L CA  1 
ATOM 1729 C C   . LEU B 2 154 ? -52.940  -19.550 -63.738 1.00 158.75 ? 155 LEU L C   1 
ATOM 1730 O O   . LEU B 2 154 ? -52.036  -19.099 -64.446 1.00 152.77 ? 155 LEU L O   1 
ATOM 1731 C CB  . LEU B 2 154 ? -52.257  -20.976 -61.800 1.00 137.10 ? 155 LEU L CB  1 
ATOM 1732 N N   . GLN B 2 155 ? -54.013  -18.843 -63.392 1.00 160.98 ? 156 GLN L N   1 
ATOM 1733 C CA  . GLN B 2 155 ? -54.234  -17.476 -63.839 1.00 156.65 ? 156 GLN L CA  1 
ATOM 1734 C C   . GLN B 2 155 ? -54.686  -16.620 -62.665 1.00 153.30 ? 156 GLN L C   1 
ATOM 1735 O O   . GLN B 2 155 ? -55.223  -17.121 -61.673 1.00 154.69 ? 156 GLN L O   1 
ATOM 1736 C CB  . GLN B 2 155 ? -55.274  -17.413 -64.968 1.00 145.44 ? 156 GLN L CB  1 
ATOM 1737 N N   . SER B 2 156 ? -54.457  -15.313 -62.787 1.00 152.42 ? 157 SER L N   1 
ATOM 1738 C CA  . SER B 2 156 ? -54.837  -14.358 -61.757 1.00 151.48 ? 157 SER L CA  1 
ATOM 1739 C C   . SER B 2 156 ? -55.331  -13.076 -62.410 1.00 152.05 ? 157 SER L C   1 
ATOM 1740 O O   . SER B 2 156 ? -54.841  -12.669 -63.467 1.00 153.94 ? 157 SER L O   1 
ATOM 1741 C CB  . SER B 2 156 ? -53.668  -14.048 -60.812 1.00 138.36 ? 157 SER L CB  1 
ATOM 1742 N N   . GLY B 2 157 ? -56.310  -12.443 -61.768 1.00 146.33 ? 158 GLY L N   1 
ATOM 1743 C CA  . GLY B 2 157 ? -56.861  -11.193 -62.246 1.00 138.80 ? 158 GLY L CA  1 
ATOM 1744 C C   . GLY B 2 157 ? -57.995  -11.314 -63.243 1.00 142.33 ? 158 GLY L C   1 
ATOM 1745 O O   . GLY B 2 157 ? -58.582  -10.287 -63.609 1.00 138.31 ? 158 GLY L O   1 
ATOM 1746 N N   . ASN B 2 158 ? -58.325  -12.527 -63.692 1.00 146.89 ? 159 ASN L N   1 
ATOM 1747 C CA  . ASN B 2 158 ? -59.406  -12.742 -64.649 1.00 135.69 ? 159 ASN L CA  1 
ATOM 1748 C C   . ASN B 2 158 ? -60.543  -13.572 -64.067 1.00 136.62 ? 159 ASN L C   1 
ATOM 1749 O O   . ASN B 2 158 ? -61.389  -14.065 -64.824 1.00 116.01 ? 159 ASN L O   1 
ATOM 1750 C CB  . ASN B 2 158 ? -58.871  -13.404 -65.923 1.00 142.25 ? 159 ASN L CB  1 
ATOM 1751 C CG  . ASN B 2 158 ? -58.180  -14.726 -65.649 1.00 136.20 ? 159 ASN L CG  1 
ATOM 1752 O OD1 . ASN B 2 158 ? -57.667  -14.956 -64.556 1.00 125.16 ? 159 ASN L OD1 1 
ATOM 1753 N ND2 . ASN B 2 158 ? -58.161  -15.602 -66.647 1.00 147.68 ? 159 ASN L ND2 1 
ATOM 1754 N N   . SER B 2 159 ? -60.587  -13.740 -62.745 1.00 144.66 ? 160 SER L N   1 
ATOM 1755 C CA  . SER B 2 159 ? -61.653  -14.467 -62.072 1.00 131.97 ? 160 SER L CA  1 
ATOM 1756 C C   . SER B 2 159 ? -62.158  -13.647 -60.894 1.00 124.21 ? 160 SER L C   1 
ATOM 1757 O O   . SER B 2 159 ? -61.399  -12.908 -60.261 1.00 133.30 ? 160 SER L O   1 
ATOM 1758 C CB  . SER B 2 159 ? -61.180  -15.842 -61.582 1.00 113.87 ? 160 SER L CB  1 
ATOM 1759 N N   . GLN B 2 160 ? -63.450  -13.781 -60.608 1.00 124.89 ? 161 GLN L N   1 
ATOM 1760 C CA  . GLN B 2 160 ? -64.088  -13.039 -59.528 1.00 122.48 ? 161 GLN L CA  1 
ATOM 1761 C C   . GLN B 2 160 ? -64.894  -13.987 -58.654 1.00 123.01 ? 161 GLN L C   1 
ATOM 1762 O O   . GLN B 2 160 ? -65.636  -14.834 -59.164 1.00 120.04 ? 161 GLN L O   1 
ATOM 1763 C CB  . GLN B 2 160 ? -64.990  -11.928 -60.075 1.00 125.96 ? 161 GLN L CB  1 
ATOM 1764 C CG  . GLN B 2 160 ? -64.238  -10.673 -60.485 1.00 124.64 ? 161 GLN L CG  1 
ATOM 1765 C CD  . GLN B 2 160 ? -65.163  -9.563  -60.937 1.00 133.17 ? 161 GLN L CD  1 
ATOM 1766 O OE1 . GLN B 2 160 ? -66.334  -9.798  -61.233 1.00 143.43 ? 161 GLN L OE1 1 
ATOM 1767 N NE2 . GLN B 2 160 ? -64.639  -8.345  -60.997 1.00 138.16 ? 161 GLN L NE2 1 
ATOM 1768 N N   . GLU B 2 161 ? -64.753  -13.832 -57.341 1.00 129.64 ? 162 GLU L N   1 
ATOM 1769 C CA  . GLU B 2 161 ? -65.481  -14.624 -56.362 1.00 119.47 ? 162 GLU L CA  1 
ATOM 1770 C C   . GLU B 2 161 ? -66.608  -13.797 -55.758 1.00 108.89 ? 162 GLU L C   1 
ATOM 1771 O O   . GLU B 2 161 ? -66.531  -12.568 -55.685 1.00 104.01 ? 162 GLU L O   1 
ATOM 1772 C CB  . GLU B 2 161 ? -64.547  -15.111 -55.253 1.00 119.35 ? 162 GLU L CB  1 
ATOM 1773 C CG  . GLU B 2 161 ? -63.556  -16.170 -55.692 1.00 125.71 ? 162 GLU L CG  1 
ATOM 1774 C CD  . GLU B 2 161 ? -63.050  -16.997 -54.529 1.00 143.59 ? 162 GLU L CD  1 
ATOM 1775 O OE1 . GLU B 2 161 ? -63.288  -16.602 -53.368 1.00 140.38 ? 162 GLU L OE1 1 
ATOM 1776 O OE2 . GLU B 2 161 ? -62.414  -18.043 -54.777 1.00 149.91 ? 162 GLU L OE2 1 
ATOM 1777 N N   . SER B 2 162 ? -67.663  -14.487 -55.327 1.00 98.86  ? 163 SER L N   1 
ATOM 1778 C CA  . SER B 2 162 ? -68.810  -13.807 -54.729 1.00 123.00 ? 163 SER L CA  1 
ATOM 1779 C C   . SER B 2 162 ? -69.586  -14.826 -53.903 1.00 140.40 ? 163 SER L C   1 
ATOM 1780 O O   . SER B 2 162 ? -70.157  -15.765 -54.464 1.00 138.03 ? 163 SER L O   1 
ATOM 1781 C CB  . SER B 2 162 ? -69.674  -13.183 -55.813 1.00 95.99  ? 163 SER L CB  1 
ATOM 1782 N N   . VAL B 2 163 ? -69.628  -14.623 -52.591 1.00 144.42 ? 164 VAL L N   1 
ATOM 1783 C CA  A VAL B 2 163 ? -70.193  -15.594 -51.673 0.71 171.75 ? 164 VAL L CA  1 
ATOM 1784 C CA  B VAL B 2 163 ? -70.193  -15.595 -51.673 0.29 157.06 ? 164 VAL L CA  1 
ATOM 1785 C C   . VAL B 2 163 ? -71.574  -15.133 -51.221 1.00 127.53 ? 164 VAL L C   1 
ATOM 1786 O O   . VAL B 2 163 ? -71.987  -14.001 -51.459 1.00 134.35 ? 164 VAL L O   1 
ATOM 1787 C CB  A VAL B 2 163 ? -69.265  -15.842 -50.459 0.71 144.06 ? 164 VAL L CB  1 
ATOM 1788 C CB  B VAL B 2 163 ? -69.265  -15.843 -50.459 0.29 150.64 ? 164 VAL L CB  1 
ATOM 1789 N N   . THR B 2 164 ? -72.302  -16.030 -50.561 1.00 101.81 ? 165 THR L N   1 
ATOM 1790 C CA  . THR B 2 164 ? -73.636  -15.772 -50.047 1.00 118.12 ? 165 THR L CA  1 
ATOM 1791 C C   . THR B 2 164 ? -73.581  -15.552 -48.533 1.00 125.99 ? 165 THR L C   1 
ATOM 1792 O O   . THR B 2 164 ? -72.507  -15.433 -47.933 1.00 121.94 ? 165 THR L O   1 
ATOM 1793 C CB  . THR B 2 164 ? -74.568  -16.929 -50.408 1.00 108.95 ? 165 THR L CB  1 
ATOM 1794 O OG1 . THR B 2 164 ? -75.879  -16.669 -49.893 1.00 110.79 ? 165 THR L OG1 1 
ATOM 1795 C CG2 . THR B 2 164 ? -74.051  -18.215 -49.798 1.00 114.77 ? 165 THR L CG2 1 
ATOM 1796 N N   . GLU B 2 165 ? -74.751  -15.487 -47.908 1.00 111.11 ? 166 GLU L N   1 
ATOM 1797 C CA  . GLU B 2 165 ? -74.874  -15.352 -46.464 1.00 103.96 ? 166 GLU L CA  1 
ATOM 1798 C C   . GLU B 2 165 ? -75.191  -16.705 -45.833 1.00 116.79 ? 166 GLU L C   1 
ATOM 1799 O O   . GLU B 2 165 ? -75.563  -17.666 -46.510 1.00 129.78 ? 166 GLU L O   1 
ATOM 1800 C CB  . GLU B 2 165 ? -75.957  -14.328 -46.113 1.00 111.53 ? 166 GLU L CB  1 
ATOM 1801 C CG  . GLU B 2 165 ? -75.460  -12.892 -46.074 1.00 117.53 ? 166 GLU L CG  1 
ATOM 1802 C CD  . GLU B 2 165 ? -76.204  -12.045 -45.060 1.00 122.18 ? 166 GLU L CD  1 
ATOM 1803 O OE1 . GLU B 2 165 ? -77.416  -11.813 -45.252 1.00 115.58 ? 166 GLU L OE1 1 
ATOM 1804 O OE2 . GLU B 2 165 ? -75.575  -11.610 -44.071 1.00 121.97 ? 166 GLU L OE2 1 
ATOM 1805 N N   . GLN B 2 166 ? -75.008  -16.785 -44.511 1.00 101.05 ? 167 GLN L N   1 
ATOM 1806 C CA  . GLN B 2 166 ? -75.274  -18.049 -43.777 1.00 95.07  ? 167 GLN L CA  1 
ATOM 1807 C C   . GLN B 2 166 ? -76.762  -18.388 -43.866 1.00 97.57  ? 167 GLN L C   1 
ATOM 1808 O O   . GLN B 2 166 ? -77.579  -17.454 -43.869 1.00 85.30  ? 167 GLN L O   1 
ATOM 1809 C CB  . GLN B 2 166 ? -74.838  -17.923 -42.318 1.00 102.82 ? 167 GLN L CB  1 
ATOM 1810 C CG  . GLN B 2 166 ? -73.422  -18.411 -42.059 1.00 99.90  ? 167 GLN L CG  1 
ATOM 1811 C CD  . GLN B 2 166 ? -73.208  -18.704 -40.595 1.00 92.41  ? 167 GLN L CD  1 
ATOM 1812 O OE1 . GLN B 2 166 ? -74.073  -18.448 -39.761 1.00 84.14  ? 167 GLN L OE1 1 
ATOM 1813 N NE2 . GLN B 2 166 ? -72.049  -19.251 -40.273 1.00 98.17  ? 167 GLN L NE2 1 
ATOM 1814 N N   . ASP B 2 167 ? -77.089  -19.680 -43.902 1.00 96.20  ? 168 ASP L N   1 
ATOM 1815 C CA  . ASP B 2 167 ? -78.499  -20.108 -44.088 1.00 104.17 ? 168 ASP L CA  1 
ATOM 1816 C C   . ASP B 2 167 ? -79.305  -19.916 -42.805 1.00 102.64 ? 168 ASP L C   1 
ATOM 1817 O O   . ASP B 2 167 ? -78.695  -19.664 -41.756 1.00 108.63 ? 168 ASP L O   1 
ATOM 1818 C CB  . ASP B 2 167 ? -78.571  -21.554 -44.572 1.00 114.16 ? 168 ASP L CB  1 
ATOM 1819 C CG  . ASP B 2 167 ? -79.711  -21.794 -45.546 1.00 126.24 ? 168 ASP L CG  1 
ATOM 1820 O OD1 . ASP B 2 167 ? -80.875  -21.603 -45.142 1.00 124.26 ? 168 ASP L OD1 1 
ATOM 1821 O OD2 . ASP B 2 167 ? -79.424  -22.169 -46.699 1.00 131.04 ? 168 ASP L OD2 1 
ATOM 1822 N N   . SER B 2 168 ? -80.628  -20.045 -42.899 1.00 101.20 ? 169 SER L N   1 
ATOM 1823 C CA  . SER B 2 168 ? -81.504  -19.794 -41.727 1.00 111.31 ? 169 SER L CA  1 
ATOM 1824 C C   . SER B 2 168 ? -81.548  -21.005 -40.798 1.00 108.62 ? 169 SER L C   1 
ATOM 1825 O O   . SER B 2 168 ? -81.419  -20.802 -39.580 1.00 114.32 ? 169 SER L O   1 
ATOM 1826 C CB  . SER B 2 168 ? -82.890  -19.434 -42.175 1.00 106.03 ? 169 SER L CB  1 
ATOM 1827 N N   . LYS B 2 169 ? -81.736  -22.208 -41.343 1.00 107.76 ? 170 LYS L N   1 
ATOM 1828 C CA  . LYS B 2 169 ? -81.910  -23.392 -40.460 1.00 108.25 ? 170 LYS L CA  1 
ATOM 1829 C C   . LYS B 2 169 ? -80.833  -24.442 -40.739 1.00 108.40 ? 170 LYS L C   1 
ATOM 1830 O O   . LYS B 2 169 ? -81.013  -25.585 -40.292 1.00 116.12 ? 170 LYS L O   1 
ATOM 1831 C CB  . LYS B 2 169 ? -83.308  -23.990 -40.645 1.00 108.58 ? 170 LYS L CB  1 
ATOM 1832 N N   . ASP B 2 170 ? -79.773  -24.078 -41.455 1.00 93.21  ? 171 ASP L N   1 
ATOM 1833 C CA  . ASP B 2 170 ? -78.656  -25.034 -41.658 1.00 87.49  ? 171 ASP L CA  1 
ATOM 1834 C C   . ASP B 2 170 ? -77.346  -24.256 -41.600 1.00 92.45  ? 171 ASP L C   1 
ATOM 1835 O O   . ASP B 2 170 ? -76.283  -24.891 -41.605 1.00 83.88  ? 171 ASP L O   1 
ATOM 1836 C CB  . ASP B 2 170 ? -78.810  -25.810 -42.965 1.00 106.36 ? 171 ASP L CB  1 
ATOM 1837 C CG  . ASP B 2 170 ? -79.290  -24.963 -44.129 1.00 118.22 ? 171 ASP L CG  1 
ATOM 1838 O OD1 . ASP B 2 170 ? -78.484  -24.725 -45.047 1.00 111.01 ? 171 ASP L OD1 1 
ATOM 1839 O OD2 . ASP B 2 170 ? -80.468  -24.560 -44.109 1.00 129.26 ? 171 ASP L OD2 1 
ATOM 1840 N N   . SER B 2 171 ? -77.439  -22.929 -41.571 1.00 93.90  ? 172 SER L N   1 
ATOM 1841 C CA  . SER B 2 171 ? -76.224  -22.090 -41.451 1.00 94.31  ? 172 SER L CA  1 
ATOM 1842 C C   . SER B 2 171 ? -75.163  -22.564 -42.446 1.00 102.07 ? 172 SER L C   1 
ATOM 1843 O O   . SER B 2 171 ? -74.081  -22.984 -41.993 1.00 76.65  ? 172 SER L O   1 
ATOM 1844 C CB  . SER B 2 171 ? -75.721  -22.125 -40.043 1.00 98.19  ? 172 SER L CB  1 
ATOM 1845 O OG  . SER B 2 171 ? -76.804  -22.102 -39.125 1.00 89.16  ? 172 SER L OG  1 
ATOM 1846 N N   . THR B 2 172 ? -75.462  -22.481 -43.748 1.00 114.23 ? 173 THR L N   1 
ATOM 1847 C CA  . THR B 2 172 ? -74.508  -22.969 -44.784 1.00 116.89 ? 173 THR L CA  1 
ATOM 1848 C C   . THR B 2 172 ? -74.623  -22.171 -46.090 1.00 123.74 ? 173 THR L C   1 
ATOM 1849 O O   . THR B 2 172 ? -74.711  -20.933 -45.996 1.00 112.69 ? 173 THR L O   1 
ATOM 1850 C CB  . THR B 2 172 ? -74.715  -24.464 -45.060 1.00 110.79 ? 173 THR L CB  1 
ATOM 1851 O OG1 . THR B 2 172 ? -76.055  -24.798 -44.701 1.00 114.00 ? 173 THR L OG1 1 
ATOM 1852 C CG2 . THR B 2 172 ? -73.752  -25.347 -44.299 1.00 112.25 ? 173 THR L CG2 1 
ATOM 1853 N N   . TYR B 2 173 ? -74.583  -22.854 -47.243 1.00 139.09 ? 174 TYR L N   1 
ATOM 1854 C CA  . TYR B 2 173 ? -74.660  -22.227 -48.603 1.00 136.29 ? 174 TYR L CA  1 
ATOM 1855 C C   . TYR B 2 173 ? -73.228  -21.962 -49.104 1.00 142.38 ? 174 TYR L C   1 
ATOM 1856 O O   . TYR B 2 173 ? -72.286  -22.163 -48.315 1.00 138.47 ? 174 TYR L O   1 
ATOM 1857 C CB  . TYR B 2 173 ? -75.619  -21.041 -48.743 1.00 125.40 ? 174 TYR L CB  1 
ATOM 1858 C CG  . TYR B 2 173 ? -76.523  -21.224 -49.954 1.00 133.50 ? 174 TYR L CG  1 
ATOM 1859 C CD1 . TYR B 2 173 ? -77.480  -22.229 -49.983 1.00 127.22 ? 174 TYR L CD1 1 
ATOM 1860 C CD2 . TYR B 2 173 ? -76.391  -20.422 -51.079 1.00 119.31 ? 174 TYR L CD2 1 
ATOM 1861 C CE1 . TYR B 2 173 ? -78.299  -22.414 -51.085 1.00 109.61 ? 174 TYR L CE1 1 
ATOM 1862 C CE2 . TYR B 2 173 ? -77.204  -20.595 -52.186 1.00 125.07 ? 174 TYR L CE2 1 
ATOM 1863 C CZ  . TYR B 2 173 ? -78.160  -21.593 -52.189 1.00 131.58 ? 174 TYR L CZ  1 
ATOM 1864 O OH  . TYR B 2 173 ? -78.964  -21.766 -53.278 1.00 145.70 ? 174 TYR L OH  1 
ATOM 1865 N N   . SER B 2 174 ? -73.061  -21.514 -50.357 1.00 136.85 ? 175 SER L N   1 
ATOM 1866 C CA  . SER B 2 174 ? -71.704  -21.412 -50.886 1.00 136.92 ? 175 SER L CA  1 
ATOM 1867 C C   . SER B 2 174 ? -71.434  -20.260 -51.847 1.00 127.34 ? 175 SER L C   1 
ATOM 1868 O O   . SER B 2 174 ? -72.284  -19.392 -52.067 1.00 140.86 ? 175 SER L O   1 
ATOM 1869 C CB  . SER B 2 174 ? -71.331  -22.718 -51.583 1.00 143.78 ? 175 SER L CB  1 
ATOM 1870 N N   . LEU B 2 175 ? -70.240  -20.280 -52.437 1.00 118.45 ? 176 LEU L N   1 
ATOM 1871 C CA  . LEU B 2 175 ? -69.681  -19.190 -53.222 1.00 130.53 ? 176 LEU L CA  1 
ATOM 1872 C C   . LEU B 2 175 ? -69.771  -19.488 -54.716 1.00 128.11 ? 176 LEU L C   1 
ATOM 1873 O O   . LEU B 2 175 ? -69.809  -20.646 -55.138 1.00 124.40 ? 176 LEU L O   1 
ATOM 1874 C CB  . LEU B 2 175 ? -68.218  -18.958 -52.823 1.00 129.28 ? 176 LEU L CB  1 
ATOM 1875 C CG  . LEU B 2 175 ? -67.342  -17.946 -53.569 1.00 133.01 ? 176 LEU L CG  1 
ATOM 1876 C CD1 . LEU B 2 175 ? -66.554  -17.083 -52.596 1.00 134.01 ? 176 LEU L CD1 1 
ATOM 1877 C CD2 . LEU B 2 175 ? -66.404  -18.656 -54.534 1.00 129.99 ? 176 LEU L CD2 1 
ATOM 1878 N N   . SER B 2 176 ? -69.800  -18.422 -55.511 1.00 137.22 ? 177 SER L N   1 
ATOM 1879 C CA  . SER B 2 176 ? -69.756  -18.499 -56.965 1.00 128.08 ? 177 SER L CA  1 
ATOM 1880 C C   . SER B 2 176 ? -68.453  -17.885 -57.457 1.00 127.39 ? 177 SER L C   1 
ATOM 1881 O O   . SER B 2 176 ? -68.081  -16.786 -57.033 1.00 128.38 ? 177 SER L O   1 
ATOM 1882 C CB  . SER B 2 176 ? -70.950  -17.774 -57.591 1.00 112.14 ? 177 SER L CB  1 
ATOM 1883 N N   . SER B 2 177 ? -67.764  -18.592 -58.349 1.00 136.14 ? 178 SER L N   1 
ATOM 1884 C CA  . SER B 2 177 ? -66.515  -18.119 -58.933 1.00 136.68 ? 178 SER L CA  1 
ATOM 1885 C C   . SER B 2 177 ? -66.664  -18.079 -60.446 1.00 141.86 ? 178 SER L C   1 
ATOM 1886 O O   . SER B 2 177 ? -66.857  -19.121 -61.081 1.00 147.99 ? 178 SER L O   1 
ATOM 1887 C CB  . SER B 2 177 ? -65.344  -19.015 -58.530 1.00 137.55 ? 178 SER L CB  1 
ATOM 1888 N N   . THR B 2 178 ? -66.568  -16.882 -61.019 1.00 146.61 ? 179 THR L N   1 
ATOM 1889 C CA  . THR B 2 178 ? -66.726  -16.677 -62.454 1.00 127.91 ? 179 THR L CA  1 
ATOM 1890 C C   . THR B 2 178 ? -65.377  -16.319 -63.061 1.00 127.79 ? 179 THR L C   1 
ATOM 1891 O O   . THR B 2 178 ? -64.764  -15.320 -62.672 1.00 126.10 ? 179 THR L O   1 
ATOM 1892 C CB  . THR B 2 178 ? -67.751  -15.578 -62.741 1.00 104.33 ? 179 THR L CB  1 
ATOM 1893 O OG1 . THR B 2 178 ? -69.063  -16.038 -62.394 1.00 118.53 ? 179 THR L OG1 1 
ATOM 1894 C CG2 . THR B 2 178 ? -67.724  -15.189 -64.208 1.00 116.95 ? 179 THR L CG2 1 
ATOM 1895 N N   . LEU B 2 179 ? -64.920  -17.134 -64.010 1.00 143.49 ? 180 LEU L N   1 
ATOM 1896 C CA  . LEU B 2 179 ? -63.706  -16.868 -64.771 1.00 141.63 ? 180 LEU L CA  1 
ATOM 1897 C C   . LEU B 2 179 ? -64.106  -16.270 -66.112 1.00 140.74 ? 180 LEU L C   1 
ATOM 1898 O O   . LEU B 2 179 ? -64.808  -16.917 -66.898 1.00 139.61 ? 180 LEU L O   1 
ATOM 1899 C CB  . LEU B 2 179 ? -62.894  -18.147 -64.975 1.00 138.42 ? 180 LEU L CB  1 
ATOM 1900 C CG  . LEU B 2 179 ? -61.652  -18.044 -65.863 1.00 121.16 ? 180 LEU L CG  1 
ATOM 1901 C CD1 . LEU B 2 179 ? -60.542  -17.291 -65.148 1.00 113.57 ? 180 LEU L CD1 1 
ATOM 1902 C CD2 . LEU B 2 179 ? -61.179  -19.423 -66.299 1.00 115.82 ? 180 LEU L CD2 1 
ATOM 1903 N N   . THR B 2 180 ? -63.657  -15.046 -66.369 1.00 138.32 ? 181 THR L N   1 
ATOM 1904 C CA  . THR B 2 180 ? -64.033  -14.288 -67.554 1.00 141.16 ? 181 THR L CA  1 
ATOM 1905 C C   . THR B 2 180 ? -62.873  -14.281 -68.540 1.00 152.41 ? 181 THR L C   1 
ATOM 1906 O O   . THR B 2 180 ? -61.746  -13.932 -68.172 1.00 150.70 ? 181 THR L O   1 
ATOM 1907 C CB  . THR B 2 180 ? -64.412  -12.853 -67.179 1.00 139.81 ? 181 THR L CB  1 
ATOM 1908 O OG1 . THR B 2 180 ? -63.350  -12.263 -66.418 1.00 136.19 ? 181 THR L OG1 1 
ATOM 1909 C CG2 . THR B 2 180 ? -65.681  -12.835 -66.343 1.00 124.81 ? 181 THR L CG2 1 
ATOM 1910 N N   . LEU B 2 181 ? -63.146  -14.667 -69.786 1.00 156.85 ? 182 LEU L N   1 
ATOM 1911 C CA  . LEU B 2 181 ? -62.129  -14.621 -70.828 1.00 151.46 ? 182 LEU L CA  1 
ATOM 1912 C C   . LEU B 2 181 ? -62.793  -14.297 -72.157 1.00 150.64 ? 182 LEU L C   1 
ATOM 1913 O O   . LEU B 2 181 ? -63.914  -14.738 -72.418 1.00 147.74 ? 182 LEU L O   1 
ATOM 1914 C CB  . LEU B 2 181 ? -61.359  -15.943 -70.927 1.00 144.48 ? 182 LEU L CB  1 
ATOM 1915 C CG  . LEU B 2 181 ? -60.096  -16.046 -70.069 1.00 134.79 ? 182 LEU L CG  1 
ATOM 1916 C CD1 . LEU B 2 181 ? -59.409  -17.387 -70.276 1.00 133.60 ? 182 LEU L CD1 1 
ATOM 1917 C CD2 . LEU B 2 181 ? -59.143  -14.896 -70.367 1.00 131.97 ? 182 LEU L CD2 1 
ATOM 1918 N N   . SER B 2 182 ? -62.091  -13.537 -72.995 1.00 157.70 ? 183 SER L N   1 
ATOM 1919 C CA  . SER B 2 182 ? -62.640  -13.121 -74.276 1.00 159.15 ? 183 SER L CA  1 
ATOM 1920 C C   . SER B 2 182 ? -62.776  -14.318 -75.219 1.00 157.28 ? 183 SER L C   1 
ATOM 1921 O O   . SER B 2 182 ? -62.357  -15.440 -74.917 1.00 167.21 ? 183 SER L O   1 
ATOM 1922 C CB  . SER B 2 182 ? -61.762  -12.042 -74.909 1.00 143.90 ? 183 SER L CB  1 
ATOM 1923 N N   . LYS B 2 183 ? -63.379  -14.063 -76.384 1.00 146.73 ? 184 LYS L N   1 
ATOM 1924 C CA  . LYS B 2 183 ? -63.566  -15.124 -77.369 1.00 152.43 ? 184 LYS L CA  1 
ATOM 1925 C C   . LYS B 2 183 ? -62.235  -15.663 -77.875 1.00 161.84 ? 184 LYS L C   1 
ATOM 1926 O O   . LYS B 2 183 ? -62.152  -16.827 -78.283 1.00 165.44 ? 184 LYS L O   1 
ATOM 1927 C CB  . LYS B 2 183 ? -64.410  -14.615 -78.538 1.00 142.11 ? 184 LYS L CB  1 
ATOM 1928 N N   . ALA B 2 184 ? -61.186  -14.837 -77.856 1.00 163.10 ? 185 ALA L N   1 
ATOM 1929 C CA  . ALA B 2 184 ? -59.867  -15.268 -78.303 1.00 167.96 ? 185 ALA L CA  1 
ATOM 1930 C C   . ALA B 2 184 ? -59.206  -16.249 -77.345 1.00 171.56 ? 185 ALA L C   1 
ATOM 1931 O O   . ALA B 2 184 ? -58.228  -16.899 -77.732 1.00 157.60 ? 185 ALA L O   1 
ATOM 1932 C CB  . ALA B 2 184 ? -58.959  -14.052 -78.502 1.00 163.29 ? 185 ALA L CB  1 
ATOM 1933 N N   . ASP B 2 185 ? -59.706  -16.372 -76.113 1.00 174.15 ? 186 ASP L N   1 
ATOM 1934 C CA  . ASP B 2 185 ? -59.140  -17.293 -75.138 1.00 165.92 ? 186 ASP L CA  1 
ATOM 1935 C C   . ASP B 2 185 ? -60.057  -18.454 -74.784 1.00 168.96 ? 186 ASP L C   1 
ATOM 1936 O O   . ASP B 2 185 ? -59.560  -19.497 -74.348 1.00 166.68 ? 186 ASP L O   1 
ATOM 1937 C CB  . ASP B 2 185 ? -58.771  -16.543 -73.848 1.00 153.36 ? 186 ASP L CB  1 
ATOM 1938 N N   . TYR B 2 186 ? -61.374  -18.302 -74.953 1.00 172.64 ? 187 TYR L N   1 
ATOM 1939 C CA  . TYR B 2 186 ? -62.286  -19.404 -74.660 1.00 168.06 ? 187 TYR L CA  1 
ATOM 1940 C C   . TYR B 2 186 ? -62.155  -20.519 -75.690 1.00 170.62 ? 187 TYR L C   1 
ATOM 1941 O O   . TYR B 2 186 ? -62.131  -21.703 -75.332 1.00 159.92 ? 187 TYR L O   1 
ATOM 1942 C CB  . TYR B 2 186 ? -63.725  -18.893 -74.599 1.00 153.10 ? 187 TYR L CB  1 
ATOM 1943 N N   . GLU B 2 187 ? -62.072  -20.163 -76.974 1.00 176.57 ? 188 GLU L N   1 
ATOM 1944 C CA  . GLU B 2 187 ? -61.878  -21.147 -78.032 1.00 177.87 ? 188 GLU L CA  1 
ATOM 1945 C C   . GLU B 2 187 ? -60.420  -21.547 -78.213 1.00 174.96 ? 188 GLU L C   1 
ATOM 1946 O O   . GLU B 2 187 ? -60.149  -22.534 -78.905 1.00 167.84 ? 188 GLU L O   1 
ATOM 1947 C CB  . GLU B 2 187 ? -62.431  -20.614 -79.359 1.00 165.40 ? 188 GLU L CB  1 
ATOM 1948 C CG  . GLU B 2 187 ? -63.952  -20.521 -79.429 1.00 160.79 ? 188 GLU L CG  1 
ATOM 1949 C CD  . GLU B 2 187 ? -64.618  -21.872 -79.642 1.00 157.99 ? 188 GLU L CD  1 
ATOM 1950 O OE1 . GLU B 2 187 ? -63.895  -22.874 -79.821 1.00 162.61 ? 188 GLU L OE1 1 
ATOM 1951 O OE2 . GLU B 2 187 ? -65.866  -21.930 -79.643 1.00 144.32 ? 188 GLU L OE2 1 
ATOM 1952 N N   . LYS B 2 188 ? -59.479  -20.811 -77.616 1.00 173.88 ? 189 LYS L N   1 
ATOM 1953 C CA  . LYS B 2 188 ? -58.070  -21.172 -77.716 1.00 164.42 ? 189 LYS L CA  1 
ATOM 1954 C C   . LYS B 2 188 ? -57.721  -22.390 -76.870 1.00 171.79 ? 189 LYS L C   1 
ATOM 1955 O O   . LYS B 2 188 ? -56.744  -23.082 -77.177 1.00 168.63 ? 189 LYS L O   1 
ATOM 1956 C CB  . LYS B 2 188 ? -57.192  -19.987 -77.310 1.00 148.23 ? 189 LYS L CB  1 
ATOM 1957 N N   . HIS B 2 189 ? -58.488  -22.666 -75.819 1.00 170.22 ? 190 HIS L N   1 
ATOM 1958 C CA  . HIS B 2 189 ? -58.268  -23.808 -74.945 1.00 160.94 ? 190 HIS L CA  1 
ATOM 1959 C C   . HIS B 2 189 ? -59.483  -24.727 -74.980 1.00 165.28 ? 190 HIS L C   1 
ATOM 1960 O O   . HIS B 2 189 ? -60.531  -24.393 -75.539 1.00 157.23 ? 190 HIS L O   1 
ATOM 1961 C CB  . HIS B 2 189 ? -57.981  -23.355 -73.507 1.00 155.10 ? 190 HIS L CB  1 
ATOM 1962 N N   . LYS B 2 190 ? -59.331  -25.906 -74.368 1.00 162.63 ? 191 LYS L N   1 
ATOM 1963 C CA  . LYS B 2 190 ? -60.407  -26.890 -74.361 1.00 156.36 ? 191 LYS L CA  1 
ATOM 1964 C C   . LYS B 2 190 ? -60.634  -27.525 -72.993 1.00 154.41 ? 191 LYS L C   1 
ATOM 1965 O O   . LYS B 2 190 ? -61.355  -28.528 -72.910 1.00 148.29 ? 191 LYS L O   1 
ATOM 1966 C CB  . LYS B 2 190 ? -60.134  -27.990 -75.396 1.00 144.66 ? 191 LYS L CB  1 
ATOM 1967 N N   . VAL B 2 191 ? -59.974  -26.990 -71.960 1.00 160.29 ? 192 VAL L N   1 
ATOM 1968 C CA  . VAL B 2 191 ? -60.168  -27.512 -70.574 1.00 156.85 ? 192 VAL L CA  1 
ATOM 1969 C C   . VAL B 2 191 ? -60.209  -26.341 -69.590 1.00 155.68 ? 192 VAL L C   1 
ATOM 1970 O O   . VAL B 2 191 ? -59.494  -25.341 -69.818 1.00 143.13 ? 192 VAL L O   1 
ATOM 1971 C CB  . VAL B 2 191 ? -59.100  -28.552 -70.181 1.00 151.76 ? 192 VAL L CB  1 
ATOM 1972 C CG1 . VAL B 2 191 ? -57.926  -27.941 -69.429 1.00 149.33 ? 192 VAL L CG1 1 
ATOM 1973 C CG2 . VAL B 2 191 ? -59.710  -29.692 -69.381 1.00 134.76 ? 192 VAL L CG2 1 
ATOM 1974 N N   . TYR B 2 192 ? -61.047  -26.457 -68.558 1.00 167.43 ? 193 TYR L N   1 
ATOM 1975 C CA  . TYR B 2 192 ? -61.183  -25.388 -67.532 1.00 167.34 ? 193 TYR L CA  1 
ATOM 1976 C C   . TYR B 2 192 ? -61.225  -26.067 -66.175 1.00 154.48 ? 193 TYR L C   1 
ATOM 1977 O O   . TYR B 2 192 ? -62.305  -26.116 -65.553 1.00 147.72 ? 193 TYR L O   1 
ATOM 1978 C CB  . TYR B 2 192 ? -62.449  -24.580 -67.837 1.00 165.84 ? 193 TYR L CB  1 
ATOM 1979 C CG  . TYR B 2 192 ? -62.665  -24.286 -69.316 1.00 158.05 ? 193 TYR L CG  1 
ATOM 1980 C CD1 . TYR B 2 192 ? -61.898  -23.336 -69.978 1.00 148.59 ? 193 TYR L CD1 1 
ATOM 1981 C CD2 . TYR B 2 192 ? -63.628  -24.967 -70.051 1.00 151.80 ? 193 TYR L CD2 1 
ATOM 1982 C CE1 . TYR B 2 192 ? -62.079  -23.075 -71.325 1.00 156.06 ? 193 TYR L CE1 1 
ATOM 1983 C CE2 . TYR B 2 192 ? -63.819  -24.715 -71.398 1.00 157.34 ? 193 TYR L CE2 1 
ATOM 1984 C CZ  . TYR B 2 192 ? -63.044  -23.764 -72.036 1.00 160.12 ? 193 TYR L CZ  1 
ATOM 1985 O OH  . TYR B 2 192 ? -63.227  -23.501 -73.363 1.00 156.24 ? 193 TYR L OH  1 
ATOM 1986 N N   . ALA B 2 193 ? -60.082  -26.583 -65.719 1.00 161.32 ? 194 ALA L N   1 
ATOM 1987 C CA  . ALA B 2 193 ? -60.067  -27.362 -64.458 1.00 166.59 ? 194 ALA L CA  1 
ATOM 1988 C C   . ALA B 2 193 ? -60.097  -26.446 -63.231 1.00 172.38 ? 194 ALA L C   1 
ATOM 1989 O O   . ALA B 2 193 ? -59.862  -25.235 -63.391 1.00 176.60 ? 194 ALA L O   1 
ATOM 1990 C CB  . ALA B 2 193 ? -58.873  -28.282 -64.434 1.00 152.42 ? 194 ALA L CB  1 
ATOM 1991 N N   . CYS B 2 194 ? -60.346  -27.018 -62.051 1.00 167.84 ? 195 CYS L N   1 
ATOM 1992 C CA  . CYS B 2 194 ? -60.467  -26.247 -60.821 1.00 166.19 ? 195 CYS L CA  1 
ATOM 1993 C C   . CYS B 2 194 ? -60.035  -27.101 -59.638 1.00 163.09 ? 195 CYS L C   1 
ATOM 1994 O O   . CYS B 2 194 ? -60.311  -28.302 -59.602 1.00 156.50 ? 195 CYS L O   1 
ATOM 1995 C CB  . CYS B 2 194 ? -61.907  -25.765 -60.618 1.00 157.33 ? 195 CYS L CB  1 
ATOM 1996 S SG  . CYS B 2 194 ? -63.120  -27.110 -60.535 1.00 207.20 ? 195 CYS L SG  1 
ATOM 1997 N N   . GLU B 2 195 ? -59.367  -26.475 -58.669 1.00 170.72 ? 196 GLU L N   1 
ATOM 1998 C CA  . GLU B 2 195 ? -58.938  -27.153 -57.450 1.00 169.34 ? 196 GLU L CA  1 
ATOM 1999 C C   . GLU B 2 195 ? -59.472  -26.391 -56.246 1.00 177.36 ? 196 GLU L C   1 
ATOM 2000 O O   . GLU B 2 195 ? -59.156  -25.211 -56.065 1.00 176.03 ? 196 GLU L O   1 
ATOM 2001 C CB  . GLU B 2 195 ? -57.411  -27.269 -57.379 1.00 163.19 ? 196 GLU L CB  1 
ATOM 2002 C CG  . GLU B 2 195 ? -56.910  -28.005 -56.142 1.00 162.24 ? 196 GLU L CG  1 
ATOM 2003 C CD  . GLU B 2 195 ? -55.400  -27.972 -56.005 1.00 152.48 ? 196 GLU L CD  1 
ATOM 2004 O OE1 . GLU B 2 195 ? -54.712  -27.822 -57.036 1.00 142.55 ? 196 GLU L OE1 1 
ATOM 2005 O OE2 . GLU B 2 195 ? -54.902  -28.096 -54.866 1.00 136.36 ? 196 GLU L OE2 1 
ATOM 2006 N N   . VAL B 2 196 ? -60.275  -27.066 -55.427 1.00 173.03 ? 197 VAL L N   1 
ATOM 2007 C CA  . VAL B 2 196 ? -60.840  -26.488 -54.214 1.00 159.73 ? 197 VAL L CA  1 
ATOM 2008 C C   . VAL B 2 196 ? -60.097  -27.058 -53.013 1.00 161.01 ? 197 VAL L C   1 
ATOM 2009 O O   . VAL B 2 196 ? -59.622  -28.199 -53.037 1.00 164.16 ? 197 VAL L O   1 
ATOM 2010 C CB  . VAL B 2 196 ? -62.356  -26.764 -54.119 1.00 143.17 ? 197 VAL L CB  1 
ATOM 2011 C CG1 . VAL B 2 196 ? -62.987  -25.903 -53.045 1.00 139.19 ? 197 VAL L CG1 1 
ATOM 2012 C CG2 . VAL B 2 196 ? -63.029  -26.534 -55.468 1.00 142.39 ? 197 VAL L CG2 1 
ATOM 2013 N N   . THR B 2 197 ? -59.984  -26.258 -51.953 1.00 169.64 ? 198 THR L N   1 
ATOM 2014 C CA  . THR B 2 197 ? -59.284  -26.658 -50.737 1.00 169.99 ? 198 THR L CA  1 
ATOM 2015 C C   . THR B 2 197 ? -60.209  -26.535 -49.534 1.00 159.47 ? 198 THR L C   1 
ATOM 2016 O O   . THR B 2 197 ? -60.848  -25.495 -49.338 1.00 154.35 ? 198 THR L O   1 
ATOM 2017 C CB  . THR B 2 197 ? -58.024  -25.812 -50.509 1.00 168.49 ? 198 THR L CB  1 
ATOM 2018 O OG1 . THR B 2 197 ? -58.397  -24.482 -50.125 1.00 178.07 ? 198 THR L OG1 1 
ATOM 2019 C CG2 . THR B 2 197 ? -57.164  -25.763 -51.767 1.00 160.46 ? 198 THR L CG2 1 
ATOM 2020 N N   . HIS B 2 198 ? -60.266  -27.597 -48.732 1.00 153.58 ? 199 HIS L N   1 
ATOM 2021 C CA  . HIS B 2 198 ? -61.001  -27.635 -47.467 1.00 153.62 ? 199 HIS L CA  1 
ATOM 2022 C C   . HIS B 2 198 ? -62.471  -27.253 -47.651 1.00 146.87 ? 199 HIS L C   1 
ATOM 2023 O O   . HIS B 2 198 ? -62.964  -26.262 -47.109 1.00 137.31 ? 199 HIS L O   1 
ATOM 2024 C CB  . HIS B 2 198 ? -60.330  -26.746 -46.416 1.00 152.69 ? 199 HIS L CB  1 
ATOM 2025 C CG  . HIS B 2 198 ? -60.591  -27.181 -45.007 1.00 142.46 ? 199 HIS L CG  1 
ATOM 2026 N ND1 . HIS B 2 198 ? -61.794  -27.723 -44.607 1.00 139.30 ? 199 HIS L ND1 1 
ATOM 2027 C CD2 . HIS B 2 198 ? -59.804  -27.157 -43.906 1.00 142.65 ? 199 HIS L CD2 1 
ATOM 2028 C CE1 . HIS B 2 198 ? -61.737  -28.011 -43.319 1.00 138.67 ? 199 HIS L CE1 1 
ATOM 2029 N NE2 . HIS B 2 198 ? -60.541  -27.678 -42.870 1.00 141.72 ? 199 HIS L NE2 1 
ATOM 2030 N N   . GLN B 2 199 ? -63.170  -28.073 -48.429 1.00 147.21 ? 200 GLN L N   1 
ATOM 2031 C CA  . GLN B 2 199 ? -64.615  -27.974 -48.573 1.00 140.20 ? 200 GLN L CA  1 
ATOM 2032 C C   . GLN B 2 199 ? -65.366  -28.843 -47.577 1.00 148.64 ? 200 GLN L C   1 
ATOM 2033 O O   . GLN B 2 199 ? -66.564  -29.075 -47.762 1.00 142.20 ? 200 GLN L O   1 
ATOM 2034 C CB  . GLN B 2 199 ? -65.041  -28.364 -49.989 1.00 119.17 ? 200 GLN L CB  1 
ATOM 2035 C CG  . GLN B 2 199 ? -65.392  -27.199 -50.879 1.00 132.08 ? 200 GLN L CG  1 
ATOM 2036 C CD  . GLN B 2 199 ? -66.705  -26.559 -50.490 1.00 150.14 ? 200 GLN L CD  1 
ATOM 2037 O OE1 . GLN B 2 199 ? -67.771  -26.960 -50.956 1.00 153.54 ? 200 GLN L OE1 1 
ATOM 2038 N NE2 . GLN B 2 199 ? -66.633  -25.543 -49.640 1.00 163.17 ? 200 GLN L NE2 1 
ATOM 2039 N N   . GLY B 2 200 ? -64.698  -29.328 -46.536 1.00 136.34 ? 201 GLY L N   1 
ATOM 2040 C CA  . GLY B 2 200 ? -65.283  -30.406 -45.758 1.00 117.17 ? 201 GLY L CA  1 
ATOM 2041 C C   . GLY B 2 200 ? -65.499  -31.636 -46.610 1.00 125.94 ? 201 GLY L C   1 
ATOM 2042 O O   . GLY B 2 200 ? -66.541  -32.294 -46.504 1.00 124.66 ? 201 GLY L O   1 
ATOM 2043 N N   . LEU B 2 201 ? -64.534  -31.949 -47.471 1.00 145.33 ? 202 LEU L N   1 
ATOM 2044 C CA  . LEU B 2 201 ? -64.668  -32.998 -48.470 1.00 148.11 ? 202 LEU L CA  1 
ATOM 2045 C C   . LEU B 2 201 ? -63.332  -33.731 -48.560 1.00 155.97 ? 202 LEU L C   1 
ATOM 2046 O O   . LEU B 2 201 ? -62.457  -33.574 -47.702 1.00 161.74 ? 202 LEU L O   1 
ATOM 2047 C CB  . LEU B 2 201 ? -65.115  -32.394 -49.809 1.00 135.18 ? 202 LEU L CB  1 
ATOM 2048 C CG  . LEU B 2 201 ? -65.928  -33.257 -50.775 1.00 131.94 ? 202 LEU L CG  1 
ATOM 2049 C CD1 . LEU B 2 201 ? -67.338  -33.461 -50.249 1.00 131.95 ? 202 LEU L CD1 1 
ATOM 2050 C CD2 . LEU B 2 201 ? -65.959  -32.613 -52.151 1.00 121.32 ? 202 LEU L CD2 1 
ATOM 2051 N N   . SER B 2 202 ? -63.167  -34.536 -49.610 1.00 151.64 ? 203 SER L N   1 
ATOM 2052 C CA  . SER B 2 202 ? -61.959  -35.328 -49.801 1.00 156.18 ? 203 SER L CA  1 
ATOM 2053 C C   . SER B 2 202 ? -61.104  -34.805 -50.948 1.00 165.05 ? 203 SER L C   1 
ATOM 2054 O O   . SER B 2 202 ? -59.920  -34.515 -50.754 1.00 165.94 ? 203 SER L O   1 
ATOM 2055 C CB  . SER B 2 202 ? -62.333  -36.798 -50.040 1.00 154.53 ? 203 SER L CB  1 
ATOM 2056 O OG  . SER B 2 202 ? -63.080  -36.945 -51.235 1.00 159.15 ? 203 SER L OG  1 
ATOM 2057 N N   . SER B 2 203 ? -61.673  -34.675 -52.142 1.00 160.45 ? 204 SER L N   1 
ATOM 2058 C CA  . SER B 2 203 ? -60.961  -34.180 -53.308 1.00 156.26 ? 204 SER L CA  1 
ATOM 2059 C C   . SER B 2 203 ? -61.806  -33.137 -54.022 1.00 153.60 ? 204 SER L C   1 
ATOM 2060 O O   . SER B 2 203 ? -63.036  -33.143 -53.901 1.00 152.13 ? 204 SER L O   1 
ATOM 2061 C CB  . SER B 2 203 ? -60.621  -35.320 -54.280 1.00 156.86 ? 204 SER L CB  1 
ATOM 2062 O OG  . SER B 2 203 ? -59.822  -36.306 -53.650 1.00 154.25 ? 204 SER L OG  1 
ATOM 2063 N N   . PRO B 2 204 ? -61.176  -32.217 -54.749 1.00 139.92 ? 205 PRO L N   1 
ATOM 2064 C CA  . PRO B 2 204 ? -61.945  -31.249 -55.537 1.00 132.63 ? 205 PRO L CA  1 
ATOM 2065 C C   . PRO B 2 204 ? -62.916  -31.958 -56.470 1.00 140.07 ? 205 PRO L C   1 
ATOM 2066 O O   . PRO B 2 204 ? -62.559  -32.924 -57.148 1.00 150.03 ? 205 PRO L O   1 
ATOM 2067 C CB  . PRO B 2 204 ? -60.860  -30.496 -56.306 1.00 140.33 ? 205 PRO L CB  1 
ATOM 2068 C CG  . PRO B 2 204 ? -59.695  -30.499 -55.369 1.00 134.96 ? 205 PRO L CG  1 
ATOM 2069 C CD  . PRO B 2 204 ? -59.758  -31.825 -54.631 1.00 130.74 ? 205 PRO L CD  1 
ATOM 2070 N N   . VAL B 2 205 ? -64.157  -31.475 -56.499 1.00 140.87 ? 206 VAL L N   1 
ATOM 2071 C CA  . VAL B 2 205 ? -65.252  -32.167 -57.171 1.00 156.47 ? 206 VAL L CA  1 
ATOM 2072 C C   . VAL B 2 205 ? -65.471  -31.581 -58.561 1.00 167.03 ? 206 VAL L C   1 
ATOM 2073 O O   . VAL B 2 205 ? -65.302  -30.376 -58.790 1.00 176.14 ? 206 VAL L O   1 
ATOM 2074 C CB  . VAL B 2 205 ? -66.541  -32.104 -56.318 1.00 137.62 ? 206 VAL L CB  1 
ATOM 2075 C CG1 . VAL B 2 205 ? -67.175  -30.718 -56.379 1.00 139.82 ? 206 VAL L CG1 1 
ATOM 2076 C CG2 . VAL B 2 205 ? -67.531  -33.180 -56.748 1.00 138.06 ? 206 VAL L CG2 1 
ATOM 2077 N N   . THR B 2 206 ? -65.833  -32.456 -59.502 1.00 160.32 ? 207 THR L N   1 
ATOM 2078 C CA  . THR B 2 206 ? -66.293  -32.090 -60.847 1.00 161.35 ? 207 THR L CA  1 
ATOM 2079 C C   . THR B 2 206 ? -65.341  -31.102 -61.533 1.00 165.19 ? 207 THR L C   1 
ATOM 2080 O O   . THR B 2 206 ? -65.674  -29.944 -61.784 1.00 169.80 ? 207 THR L O   1 
ATOM 2081 C CB  . THR B 2 206 ? -67.717  -31.524 -60.796 1.00 160.90 ? 207 THR L CB  1 
ATOM 2082 O OG1 . THR B 2 206 ? -67.739  -30.337 -59.991 1.00 181.54 ? 207 THR L OG1 1 
ATOM 2083 C CG2 . THR B 2 206 ? -68.680  -32.549 -60.213 1.00 148.85 ? 207 THR L CG2 1 
ATOM 2084 N N   . LYS B 2 207 ? -64.135  -31.593 -61.828 1.00 163.43 ? 208 LYS L N   1 
ATOM 2085 C CA  . LYS B 2 207 ? -63.097  -30.790 -62.465 1.00 169.23 ? 208 LYS L CA  1 
ATOM 2086 C C   . LYS B 2 207 ? -62.950  -31.085 -63.957 1.00 179.95 ? 208 LYS L C   1 
ATOM 2087 O O   . LYS B 2 207 ? -61.886  -30.830 -64.533 1.00 165.21 ? 208 LYS L O   1 
ATOM 2088 C CB  . LYS B 2 207 ? -61.758  -31.001 -61.756 1.00 154.29 ? 208 LYS L CB  1 
ATOM 2089 C CG  . LYS B 2 207 ? -61.839  -30.960 -60.240 1.00 137.09 ? 208 LYS L CG  1 
ATOM 2090 C CD  . LYS B 2 207 ? -60.735  -31.797 -59.609 1.00 117.18 ? 208 LYS L CD  1 
ATOM 2091 C CE  . LYS B 2 207 ? -59.367  -31.439 -60.164 1.00 118.66 ? 208 LYS L CE  1 
ATOM 2092 N NZ  . LYS B 2 207 ? -58.887  -30.125 -59.661 1.00 135.15 ? 208 LYS L NZ  1 
ATOM 2093 N N   . SER B 2 208 ? -63.985  -31.631 -64.590 1.00 187.16 ? 209 SER L N   1 
ATOM 2094 C CA  . SER B 2 208 ? -63.969  -31.930 -66.017 1.00 166.77 ? 209 SER L CA  1 
ATOM 2095 C C   . SER B 2 208 ? -64.718  -30.835 -66.770 1.00 164.57 ? 209 SER L C   1 
ATOM 2096 O O   . SER B 2 208 ? -65.895  -30.579 -66.492 1.00 161.36 ? 209 SER L O   1 
ATOM 2097 C CB  . SER B 2 208 ? -64.596  -33.297 -66.287 1.00 151.51 ? 209 SER L CB  1 
ATOM 2098 N N   . PHE B 2 209 ? -64.035  -30.187 -67.714 1.00 166.20 ? 210 PHE L N   1 
ATOM 2099 C CA  . PHE B 2 209 ? -64.580  -29.034 -68.429 1.00 163.42 ? 210 PHE L CA  1 
ATOM 2100 C C   . PHE B 2 209 ? -64.203  -29.062 -69.910 1.00 160.40 ? 210 PHE L C   1 
ATOM 2101 O O   . PHE B 2 209 ? -63.713  -28.078 -70.468 1.00 160.73 ? 210 PHE L O   1 
ATOM 2102 C CB  . PHE B 2 209 ? -64.120  -27.734 -67.780 1.00 156.54 ? 210 PHE L CB  1 
ATOM 2103 N N   . ASN B 2 210 ? -64.523  -30.181 -70.562 1.00 160.92 ? 211 ASN L N   1 
ATOM 2104 C CA  . ASN B 2 210 ? -64.242  -30.318 -72.015 1.00 159.79 ? 211 ASN L CA  1 
ATOM 2105 C C   . ASN B 2 210 ? -64.998  -29.242 -72.801 1.00 158.93 ? 211 ASN L C   1 
ATOM 2106 O O   . ASN B 2 210 ? -66.205  -29.062 -72.547 1.00 150.20 ? 211 ASN L O   1 
ATOM 2107 C CB  . ASN B 2 210 ? -64.613  -31.714 -72.514 1.00 151.32 ? 211 ASN L CB  1 
ATOM 2108 N N   . ARG B 2 211 ? -64.313  -28.572 -73.733 1.00 156.48 ? 212 ARG L N   1 
ATOM 2109 C CA  . ARG B 2 211 ? -64.956  -27.518 -74.562 1.00 148.74 ? 212 ARG L CA  1 
ATOM 2110 C C   . ARG B 2 211 ? -66.106  -28.138 -75.364 1.00 146.76 ? 212 ARG L C   1 
ATOM 2111 O O   . ARG B 2 211 ? -65.819  -28.941 -76.270 1.00 143.03 ? 212 ARG L O   1 
ATOM 2112 C CB  . ARG B 2 211 ? -63.907  -26.864 -75.466 1.00 137.36 ? 212 ARG L CB  1 
ATOM 2113 C CG  . ARG B 2 211 ? -64.479  -26.008 -76.586 1.00 139.26 ? 212 ARG L CG  1 
ATOM 2114 C CD  . ARG B 2 211 ? -64.128  -24.539 -76.453 1.00 137.34 ? 212 ARG L CD  1 
ATOM 2115 N NE  . ARG B 2 211 ? -65.304  -23.684 -76.534 1.00 138.24 ? 212 ARG L NE  1 
ATOM 2116 C CZ  . ARG B 2 211 ? -66.495  -24.076 -76.972 1.00 141.21 ? 212 ARG L CZ  1 
ATOM 2117 N NH1 . ARG B 2 211 ? -67.430  -24.443 -76.113 1.00 133.16 ? 212 ARG L NH1 1 
ATOM 2118 N NH2 . ARG B 2 211 ? -66.754  -24.087 -78.268 1.00 130.72 ? 212 ARG L NH2 1 
ATOM 2119 N N   . GLY B 2 212 ? -67.353  -27.792 -75.029 1.00 142.90 ? 213 GLY L N   1 
ATOM 2120 C CA  . GLY B 2 212 ? -68.520  -28.301 -75.778 1.00 144.74 ? 213 GLY L CA  1 
ATOM 2121 C C   . GLY B 2 212 ? -69.606  -28.832 -74.857 1.00 142.30 ? 213 GLY L C   1 
ATOM 2122 O O   . GLY B 2 212 ? -69.288  -29.115 -73.688 1.00 135.62 ? 213 GLY L O   1 
ATOM 2123 N N   . GLU B 2 213 ? -70.841  -28.972 -75.361 1.00 145.56 ? 214 GLU L N   1 
ATOM 2124 C CA  . GLU B 2 213 ? -71.933  -29.425 -74.506 1.00 148.86 ? 214 GLU L CA  1 
ATOM 2125 C C   . GLU B 2 213 ? -72.237  -30.901 -74.735 1.00 153.93 ? 214 GLU L C   1 
ATOM 2126 O O   . GLU B 2 213 ? -73.178  -31.247 -75.449 1.00 158.40 ? 214 GLU L O   1 
ATOM 2127 C CB  . GLU B 2 213 ? -73.190  -28.587 -74.752 1.00 143.30 ? 214 GLU L CB  1 
ATOM 2128 N N   . GLN C 3 1   ? -93.624  8.402   -30.235 1.00 94.66  ? 1   GLN H N   1 
ATOM 2129 C CA  . GLN C 3 1   ? -92.332  7.796   -30.532 1.00 95.62  ? 1   GLN H CA  1 
ATOM 2130 C C   . GLN C 3 1   ? -91.653  8.507   -31.697 1.00 88.60  ? 1   GLN H C   1 
ATOM 2131 O O   . GLN C 3 1   ? -92.202  8.577   -32.797 1.00 90.59  ? 1   GLN H O   1 
ATOM 2132 C CB  . GLN C 3 1   ? -92.494  6.305   -30.845 1.00 101.92 ? 1   GLN H CB  1 
ATOM 2133 C CG  . GLN C 3 1   ? -93.069  5.481   -29.699 1.00 121.27 ? 1   GLN H CG  1 
ATOM 2134 C CD  . GLN C 3 1   ? -94.586  5.517   -29.642 1.00 133.75 ? 1   GLN H CD  1 
ATOM 2135 O OE1 . GLN C 3 1   ? -95.213  6.497   -30.043 1.00 132.78 ? 1   GLN H OE1 1 
ATOM 2136 N NE2 . GLN C 3 1   ? -95.183  4.442   -29.137 1.00 129.27 ? 1   GLN H NE2 1 
ATOM 2137 N N   . VAL C 3 2   ? -90.454  9.034   -31.450 1.00 69.08  ? 2   VAL H N   1 
ATOM 2138 C CA  . VAL C 3 2   ? -89.731  9.767   -32.482 1.00 75.15  ? 2   VAL H CA  1 
ATOM 2139 C C   . VAL C 3 2   ? -89.165  8.787   -33.500 1.00 79.34  ? 2   VAL H C   1 
ATOM 2140 O O   . VAL C 3 2   ? -88.524  7.791   -33.139 1.00 89.25  ? 2   VAL H O   1 
ATOM 2141 C CB  . VAL C 3 2   ? -88.619  10.623  -31.860 1.00 71.90  ? 2   VAL H CB  1 
ATOM 2142 C CG1 . VAL C 3 2   ? -87.998  11.523  -32.915 1.00 69.18  ? 2   VAL H CG1 1 
ATOM 2143 C CG2 . VAL C 3 2   ? -89.165  11.445  -30.705 1.00 73.96  ? 2   VAL H CG2 1 
ATOM 2144 N N   . GLN C 3 3   ? -89.397  9.067   -34.780 1.00 74.05  ? 3   GLN H N   1 
ATOM 2145 C CA  . GLN C 3 3   ? -88.866  8.233   -35.849 1.00 84.21  ? 3   GLN H CA  1 
ATOM 2146 C C   . GLN C 3 3   ? -88.535  9.113   -37.044 1.00 75.19  ? 3   GLN H C   1 
ATOM 2147 O O   . GLN C 3 3   ? -89.011  10.244  -37.158 1.00 75.65  ? 3   GLN H O   1 
ATOM 2148 C CB  . GLN C 3 3   ? -89.847  7.123   -36.246 1.00 84.28  ? 3   GLN H CB  1 
ATOM 2149 C CG  . GLN C 3 3   ? -91.312  7.495   -36.094 1.00 88.81  ? 3   GLN H CG  1 
ATOM 2150 C CD  . GLN C 3 3   ? -92.238  6.327   -36.379 1.00 94.59  ? 3   GLN H CD  1 
ATOM 2151 O OE1 . GLN C 3 3   ? -92.336  5.860   -37.515 1.00 99.68  ? 3   GLN H OE1 1 
ATOM 2152 N NE2 . GLN C 3 3   ? -92.918  5.844   -35.345 1.00 86.96  ? 3   GLN H NE2 1 
ATOM 2153 N N   . LEU C 3 4   ? -87.698  8.585   -37.931 1.00 65.16  ? 4   LEU H N   1 
ATOM 2154 C CA  . LEU C 3 4   ? -87.255  9.311   -39.112 1.00 73.78  ? 4   LEU H CA  1 
ATOM 2155 C C   . LEU C 3 4   ? -87.575  8.498   -40.359 1.00 83.19  ? 4   LEU H C   1 
ATOM 2156 O O   . LEU C 3 4   ? -87.275  7.300   -40.419 1.00 92.88  ? 4   LEU H O   1 
ATOM 2157 C CB  . LEU C 3 4   ? -85.756  9.617   -39.037 1.00 69.45  ? 4   LEU H CB  1 
ATOM 2158 C CG  . LEU C 3 4   ? -85.298  10.301  -37.744 1.00 59.04  ? 4   LEU H CG  1 
ATOM 2159 C CD1 . LEU C 3 4   ? -83.779  10.395  -37.677 1.00 49.97  ? 4   LEU H CD1 1 
ATOM 2160 C CD2 . LEU C 3 4   ? -85.935  11.674  -37.593 1.00 51.90  ? 4   LEU H CD2 1 
ATOM 2161 N N   . VAL C 3 5   ? -88.186  9.151   -41.344 1.00 79.26  ? 5   VAL H N   1 
ATOM 2162 C CA  . VAL C 3 5   ? -88.537  8.532   -42.618 1.00 88.44  ? 5   VAL H CA  1 
ATOM 2163 C C   . VAL C 3 5   ? -87.727  9.216   -43.710 1.00 71.93  ? 5   VAL H C   1 
ATOM 2164 O O   . VAL C 3 5   ? -87.806  10.439  -43.874 1.00 76.61  ? 5   VAL H O   1 
ATOM 2165 C CB  . VAL C 3 5   ? -90.042  8.634   -42.912 1.00 71.60  ? 5   VAL H CB  1 
ATOM 2166 C CG1 . VAL C 3 5   ? -90.345  8.072   -44.289 1.00 81.17  ? 5   VAL H CG1 1 
ATOM 2167 C CG2 . VAL C 3 5   ? -90.843  7.905   -41.845 1.00 57.80  ? 5   VAL H CG2 1 
ATOM 2168 N N   . GLU C 3 6   ? -86.957  8.432   -44.455 1.00 71.23  ? 6   GLU H N   1 
ATOM 2169 C CA  . GLU C 3 6   ? -86.081  8.964   -45.488 1.00 87.90  ? 6   GLU H CA  1 
ATOM 2170 C C   . GLU C 3 6   ? -86.725  8.834   -46.867 1.00 88.02  ? 6   GLU H C   1 
ATOM 2171 O O   . GLU C 3 6   ? -87.799  8.251   -47.035 1.00 83.06  ? 6   GLU H O   1 
ATOM 2172 C CB  . GLU C 3 6   ? -84.727  8.249   -45.462 1.00 82.91  ? 6   GLU H CB  1 
ATOM 2173 C CG  . GLU C 3 6   ? -83.987  8.372   -44.146 1.00 63.70  ? 6   GLU H CG  1 
ATOM 2174 C CD  . GLU C 3 6   ? -82.521  8.009   -44.269 1.00 77.74  ? 6   GLU H CD  1 
ATOM 2175 O OE1 . GLU C 3 6   ? -81.940  8.247   -45.349 1.00 68.91  ? 6   GLU H OE1 1 
ATOM 2176 O OE2 . GLU C 3 6   ? -81.951  7.485   -43.290 1.00 79.31  ? 6   GLU H OE2 1 
ATOM 2177 N N   . SER C 3 7   ? -86.043  9.395   -47.862 1.00 85.18  ? 7   SER H N   1 
ATOM 2178 C CA  . SER C 3 7   ? -86.516  9.366   -49.237 1.00 95.85  ? 7   SER H CA  1 
ATOM 2179 C C   . SER C 3 7   ? -86.148  8.037   -49.898 1.00 103.32 ? 7   SER H C   1 
ATOM 2180 O O   . SER C 3 7   ? -85.462  7.190   -49.319 1.00 101.00 ? 7   SER H O   1 
ATOM 2181 C CB  . SER C 3 7   ? -85.945  10.548  -50.016 1.00 79.92  ? 7   SER H CB  1 
ATOM 2182 O OG  . SER C 3 7   ? -84.535  10.612  -49.885 1.00 80.22  ? 7   SER H OG  1 
ATOM 2183 N N   . GLY C 3 8   ? -86.612  7.853   -51.139 1.00 90.40  ? 8   GLY H N   1 
ATOM 2184 C CA  . GLY C 3 8   ? -86.358  6.625   -51.862 1.00 81.62  ? 8   GLY H CA  1 
ATOM 2185 C C   . GLY C 3 8   ? -84.930  6.519   -52.368 1.00 91.44  ? 8   GLY H C   1 
ATOM 2186 O O   . GLY C 3 8   ? -84.138  7.458   -52.299 1.00 94.86  ? 8   GLY H O   1 
ATOM 2187 N N   . ALA C 3 9   ? -84.603  5.336   -52.883 1.00 85.63  ? 9   ALA H N   1 
ATOM 2188 C CA  . ALA C 3 9   ? -83.263  5.089   -53.397 1.00 90.14  ? 9   ALA H CA  1 
ATOM 2189 C C   . ALA C 3 9   ? -83.003  5.926   -54.646 1.00 95.41  ? 9   ALA H C   1 
ATOM 2190 O O   . ALA C 3 9   ? -83.911  6.212   -55.432 1.00 78.05  ? 9   ALA H O   1 
ATOM 2191 C CB  . ALA C 3 9   ? -83.072  3.604   -53.707 1.00 90.03  ? 9   ALA H CB  1 
ATOM 2192 N N   . GLU C 3 10  ? -81.744  6.325   -54.821 1.00 92.27  ? 10  GLU H N   1 
ATOM 2193 C CA  . GLU C 3 10  ? -81.348  7.212   -55.904 1.00 85.52  ? 10  GLU H CA  1 
ATOM 2194 C C   . GLU C 3 10  ? -80.137  6.646   -56.633 1.00 96.86  ? 10  GLU H C   1 
ATOM 2195 O O   . GLU C 3 10  ? -79.240  6.064   -56.014 1.00 95.67  ? 10  GLU H O   1 
ATOM 2196 C CB  . GLU C 3 10  ? -81.020  8.622   -55.380 1.00 95.71  ? 10  GLU H CB  1 
ATOM 2197 C CG  . GLU C 3 10  ? -82.090  9.240   -54.484 1.00 109.15 ? 10  GLU H CG  1 
ATOM 2198 C CD  . GLU C 3 10  ? -83.249  9.840   -55.262 1.00 113.50 ? 10  GLU H CD  1 
ATOM 2199 O OE1 . GLU C 3 10  ? -83.999  9.076   -55.906 1.00 117.78 ? 10  GLU H OE1 1 
ATOM 2200 O OE2 . GLU C 3 10  ? -83.414  11.078  -55.224 1.00 113.89 ? 10  GLU H OE2 1 
ATOM 2201 N N   . ALA C 3 11  ? -80.118  6.823   -57.952 1.00 112.13 ? 11  ALA H N   1 
ATOM 2202 C CA  . ALA C 3 11  ? -78.963  6.502   -58.780 1.00 103.25 ? 11  ALA H CA  1 
ATOM 2203 C C   . ALA C 3 11  ? -78.619  7.737   -59.596 1.00 93.70  ? 11  ALA H C   1 
ATOM 2204 O O   . ALA C 3 11  ? -79.480  8.274   -60.301 1.00 95.38  ? 11  ALA H O   1 
ATOM 2205 C CB  . ALA C 3 11  ? -79.244  5.306   -59.694 1.00 109.17 ? 11  ALA H CB  1 
ATOM 2206 N N   . LYS C 3 12  ? -77.374  8.194   -59.493 1.00 98.02  ? 12  LYS H N   1 
ATOM 2207 C CA  . LYS C 3 12  ? -76.955  9.436   -60.123 1.00 105.60 ? 12  LYS H CA  1 
ATOM 2208 C C   . LYS C 3 12  ? -75.631  9.243   -60.850 1.00 105.44 ? 12  LYS H C   1 
ATOM 2209 O O   . LYS C 3 12  ? -74.777  8.460   -60.425 1.00 105.28 ? 12  LYS H O   1 
ATOM 2210 C CB  . LYS C 3 12  ? -76.823  10.571  -59.092 1.00 112.04 ? 12  LYS H CB  1 
ATOM 2211 C CG  . LYS C 3 12  ? -78.084  10.825  -58.271 1.00 84.88  ? 12  LYS H CG  1 
ATOM 2212 C CD  . LYS C 3 12  ? -78.353  12.310  -58.115 1.00 83.76  ? 12  LYS H CD  1 
ATOM 2213 C CE  . LYS C 3 12  ? -78.604  12.968  -59.464 1.00 115.29 ? 12  LYS H CE  1 
ATOM 2214 N NZ  . LYS C 3 12  ? -78.704  14.451  -59.364 1.00 113.76 ? 12  LYS H NZ  1 
ATOM 2215 N N   . LYS C 3 13  ? -75.475  9.972   -61.955 1.00 94.17  ? 13  LYS H N   1 
ATOM 2216 C CA  . LYS C 3 13  ? -74.243  9.942   -62.725 1.00 92.43  ? 13  LYS H CA  1 
ATOM 2217 C C   . LYS C 3 13  ? -73.144  10.720  -62.000 1.00 88.79  ? 13  LYS H C   1 
ATOM 2218 O O   . LYS C 3 13  ? -73.431  11.617  -61.204 1.00 96.01  ? 13  LYS H O   1 
ATOM 2219 C CB  . LYS C 3 13  ? -74.485  10.518  -64.119 1.00 113.54 ? 13  LYS H CB  1 
ATOM 2220 C CG  . LYS C 3 13  ? -75.088  11.916  -64.123 1.00 123.66 ? 13  LYS H CG  1 
ATOM 2221 C CD  . LYS C 3 13  ? -74.966  12.575  -65.492 1.00 128.54 ? 13  LYS H CD  1 
ATOM 2222 C CE  . LYS C 3 13  ? -75.771  11.820  -66.542 1.00 128.60 ? 13  LYS H CE  1 
ATOM 2223 N NZ  . LYS C 3 13  ? -75.803  12.531  -67.854 1.00 92.11  ? 13  LYS H NZ  1 
ATOM 2224 N N   . PRO C 3 14  ? -71.875  10.393  -62.258 1.00 85.72  ? 14  PRO H N   1 
ATOM 2225 C CA  . PRO C 3 14  ? -70.780  11.050  -61.529 1.00 95.59  ? 14  PRO H CA  1 
ATOM 2226 C C   . PRO C 3 14  ? -70.736  12.550  -61.782 1.00 100.98 ? 14  PRO H C   1 
ATOM 2227 O O   . PRO C 3 14  ? -71.104  13.037  -62.853 1.00 118.55 ? 14  PRO H O   1 
ATOM 2228 C CB  . PRO C 3 14  ? -69.521  10.364  -62.075 1.00 75.77  ? 14  PRO H CB  1 
ATOM 2229 C CG  . PRO C 3 14  ? -69.991  9.077   -62.627 1.00 85.39  ? 14  PRO H CG  1 
ATOM 2230 C CD  . PRO C 3 14  ? -71.380  9.323   -63.141 1.00 86.58  ? 14  PRO H CD  1 
ATOM 2231 N N   . GLY C 3 15  ? -70.280  13.283  -60.769 1.00 87.21  ? 15  GLY H N   1 
ATOM 2232 C CA  . GLY C 3 15  ? -70.129  14.718  -60.865 1.00 84.75  ? 15  GLY H CA  1 
ATOM 2233 C C   . GLY C 3 15  ? -71.391  15.523  -60.646 1.00 98.58  ? 15  GLY H C   1 
ATOM 2234 O O   . GLY C 3 15  ? -71.335  16.757  -60.717 1.00 112.56 ? 15  GLY H O   1 
ATOM 2235 N N   . SER C 3 16  ? -72.523  14.875  -60.384 1.00 96.40  ? 16  SER H N   1 
ATOM 2236 C CA  . SER C 3 16  ? -73.784  15.563  -60.167 1.00 97.33  ? 16  SER H CA  1 
ATOM 2237 C C   . SER C 3 16  ? -74.057  15.691  -58.666 1.00 106.96 ? 16  SER H C   1 
ATOM 2238 O O   . SER C 3 16  ? -73.200  15.401  -57.823 1.00 90.61  ? 16  SER H O   1 
ATOM 2239 C CB  . SER C 3 16  ? -74.913  14.836  -60.904 1.00 97.16  ? 16  SER H CB  1 
ATOM 2240 O OG  . SER C 3 16  ? -74.770  13.430  -60.820 1.00 101.30 ? 16  SER H OG  1 
ATOM 2241 N N   . SER C 3 17  ? -75.259  16.148  -58.324 1.00 105.88 ? 17  SER H N   1 
ATOM 2242 C CA  . SER C 3 17  ? -75.645  16.409  -56.945 1.00 91.87  ? 17  SER H CA  1 
ATOM 2243 C C   . SER C 3 17  ? -76.832  15.539  -56.560 1.00 94.00  ? 17  SER H C   1 
ATOM 2244 O O   . SER C 3 17  ? -77.790  15.403  -57.328 1.00 92.99  ? 17  SER H O   1 
ATOM 2245 C CB  . SER C 3 17  ? -76.008  17.884  -56.740 1.00 99.51  ? 17  SER H CB  1 
ATOM 2246 O OG  . SER C 3 17  ? -77.187  18.223  -57.451 1.00 119.58 ? 17  SER H OG  1 
ATOM 2247 N N   . VAL C 3 18  ? -76.772  14.966  -55.361 1.00 102.77 ? 18  VAL H N   1 
ATOM 2248 C CA  . VAL C 3 18  ? -77.856  14.163  -54.810 1.00 95.46  ? 18  VAL H CA  1 
ATOM 2249 C C   . VAL C 3 18  ? -78.353  14.834  -53.537 1.00 78.85  ? 18  VAL H C   1 
ATOM 2250 O O   . VAL C 3 18  ? -77.560  15.360  -52.749 1.00 57.47  ? 18  VAL H O   1 
ATOM 2251 C CB  . VAL C 3 18  ? -77.412  12.706  -54.551 1.00 85.01  ? 18  VAL H CB  1 
ATOM 2252 C CG1 . VAL C 3 18  ? -76.276  12.649  -53.541 1.00 80.64  ? 18  VAL H CG1 1 
ATOM 2253 C CG2 . VAL C 3 18  ? -78.590  11.861  -54.091 1.00 72.97  ? 18  VAL H CG2 1 
ATOM 2254 N N   . LYS C 3 19  ? -79.674  14.862  -53.362 1.00 69.28  ? 19  LYS H N   1 
ATOM 2255 C CA  . LYS C 3 19  ? -80.299  15.498  -52.209 1.00 57.80  ? 19  LYS H CA  1 
ATOM 2256 C C   . LYS C 3 19  ? -81.254  14.508  -51.559 1.00 78.86  ? 19  LYS H C   1 
ATOM 2257 O O   . LYS C 3 19  ? -82.239  14.093  -52.177 1.00 73.22  ? 19  LYS H O   1 
ATOM 2258 C CB  . LYS C 3 19  ? -81.036  16.780  -52.613 1.00 72.29  ? 19  LYS H CB  1 
ATOM 2259 C CG  . LYS C 3 19  ? -81.656  17.532  -51.441 1.00 93.47  ? 19  LYS H CG  1 
ATOM 2260 C CD  . LYS C 3 19  ? -82.544  18.669  -51.910 1.00 78.89  ? 19  LYS H CD  1 
ATOM 2261 C CE  . LYS C 3 19  ? -81.715  19.783  -52.533 1.00 99.11  ? 19  LYS H CE  1 
ATOM 2262 N NZ  . LYS C 3 19  ? -80.902  20.516  -51.525 1.00 94.01  ? 19  LYS H NZ  1 
ATOM 2263 N N   . VAL C 3 20  ? -80.972  14.155  -50.307 1.00 95.07  ? 20  VAL H N   1 
ATOM 2264 C CA  . VAL C 3 20  ? -81.728  13.154  -49.562 1.00 88.30  ? 20  VAL H CA  1 
ATOM 2265 C C   . VAL C 3 20  ? -82.500  13.841  -48.445 1.00 75.61  ? 20  VAL H C   1 
ATOM 2266 O O   . VAL C 3 20  ? -81.993  14.767  -47.799 1.00 71.33  ? 20  VAL H O   1 
ATOM 2267 C CB  . VAL C 3 20  ? -80.807  12.053  -48.998 1.00 73.83  ? 20  VAL H CB  1 
ATOM 2268 C CG1 . VAL C 3 20  ? -81.632  10.940  -48.367 1.00 65.52  ? 20  VAL H CG1 1 
ATOM 2269 C CG2 . VAL C 3 20  ? -79.921  11.496  -50.097 1.00 86.56  ? 20  VAL H CG2 1 
ATOM 2270 N N   . SER C 3 21  ? -83.727  13.379  -48.220 1.00 60.39  ? 21  SER H N   1 
ATOM 2271 C CA  . SER C 3 21  ? -84.655  13.958  -47.263 1.00 58.92  ? 21  SER H CA  1 
ATOM 2272 C C   . SER C 3 21  ? -84.775  13.072  -46.027 1.00 91.13  ? 21  SER H C   1 
ATOM 2273 O O   . SER C 3 21  ? -84.479  11.875  -46.059 1.00 99.63  ? 21  SER H O   1 
ATOM 2274 C CB  . SER C 3 21  ? -86.031  14.153  -47.911 1.00 53.47  ? 21  SER H CB  1 
ATOM 2275 O OG  . SER C 3 21  ? -87.049  14.306  -46.941 1.00 71.06  ? 21  SER H OG  1 
ATOM 2276 N N   . CYS C 3 22  ? -85.208  13.688  -44.926 1.00 83.89  ? 22  CYS H N   1 
ATOM 2277 C CA  . CYS C 3 22  ? -85.433  12.972  -43.672 1.00 62.13  ? 22  CYS H CA  1 
ATOM 2278 C C   . CYS C 3 22  ? -86.513  13.724  -42.907 1.00 69.93  ? 22  CYS H C   1 
ATOM 2279 O O   . CYS C 3 22  ? -86.295  14.865  -42.492 1.00 72.95  ? 22  CYS H O   1 
ATOM 2280 C CB  . CYS C 3 22  ? -84.142  12.868  -42.859 1.00 76.29  ? 22  CYS H CB  1 
ATOM 2281 S SG  . CYS C 3 22  ? -84.286  11.998  -41.268 1.00 92.44  ? 22  CYS H SG  1 
ATOM 2282 N N   . LYS C 3 23  ? -87.677  13.101  -42.735 1.00 77.65  ? 23  LYS H N   1 
ATOM 2283 C CA  . LYS C 3 23  ? -88.804  13.706  -42.039 1.00 76.16  ? 23  LYS H CA  1 
ATOM 2284 C C   . LYS C 3 23  ? -88.976  13.065  -40.668 1.00 82.70  ? 23  LYS H C   1 
ATOM 2285 O O   . LYS C 3 23  ? -88.933  11.837  -40.536 1.00 90.34  ? 23  LYS H O   1 
ATOM 2286 C CB  . LYS C 3 23  ? -90.094  13.557  -42.849 1.00 67.36  ? 23  LYS H CB  1 
ATOM 2287 C CG  . LYS C 3 23  ? -91.325  14.147  -42.176 1.00 80.97  ? 23  LYS H CG  1 
ATOM 2288 C CD  . LYS C 3 23  ? -92.577  13.865  -42.990 1.00 97.49  ? 23  LYS H CD  1 
ATOM 2289 C CE  . LYS C 3 23  ? -93.806  14.484  -42.350 1.00 93.62  ? 23  LYS H CE  1 
ATOM 2290 N NZ  . LYS C 3 23  ? -93.748  15.970  -42.362 1.00 92.99  ? 23  LYS H NZ  1 
ATOM 2291 N N   . ILE C 3 24  ? -89.183  13.902  -39.652 1.00 80.08  ? 24  ILE H N   1 
ATOM 2292 C CA  . ILE C 3 24  ? -89.265  13.463  -38.263 1.00 79.63  ? 24  ILE H CA  1 
ATOM 2293 C C   . ILE C 3 24  ? -90.729  13.355  -37.860 1.00 83.95  ? 24  ILE H C   1 
ATOM 2294 O O   . ILE C 3 24  ? -91.535  14.245  -38.161 1.00 92.34  ? 24  ILE H O   1 
ATOM 2295 C CB  . ILE C 3 24  ? -88.504  14.421  -37.328 1.00 77.32  ? 24  ILE H CB  1 
ATOM 2296 C CG1 . ILE C 3 24  ? -88.743  14.046  -35.861 1.00 83.55  ? 24  ILE H CG1 1 
ATOM 2297 C CG2 . ILE C 3 24  ? -88.903  15.867  -37.595 1.00 82.06  ? 24  ILE H CG2 1 
ATOM 2298 C CD1 . ILE C 3 24  ? -87.988  14.907  -34.871 1.00 73.17  ? 24  ILE H CD1 1 
ATOM 2299 N N   . SER C 3 25  ? -91.075  12.260  -37.188 1.00 85.68  ? 25  SER H N   1 
ATOM 2300 C CA  . SER C 3 25  ? -92.411  12.027  -36.661 1.00 78.57  ? 25  SER H CA  1 
ATOM 2301 C C   . SER C 3 25  ? -92.328  11.829  -35.155 1.00 94.25  ? 25  SER H C   1 
ATOM 2302 O O   . SER C 3 25  ? -91.416  11.160  -34.656 1.00 99.88  ? 25  SER H O   1 
ATOM 2303 C CB  . SER C 3 25  ? -93.059  10.801  -37.314 1.00 90.76  ? 25  SER H CB  1 
ATOM 2304 O OG  . SER C 3 25  ? -92.845  10.794  -38.716 1.00 106.44 ? 25  SER H OG  1 
ATOM 2305 N N   . GLY C 3 26  ? -93.283  12.411  -34.433 1.00 90.04  ? 26  GLY H N   1 
ATOM 2306 C CA  . GLY C 3 26  ? -93.320  12.290  -32.990 1.00 65.18  ? 26  GLY H CA  1 
ATOM 2307 C C   . GLY C 3 26  ? -92.453  13.271  -32.236 1.00 79.53  ? 26  GLY H C   1 
ATOM 2308 O O   . GLY C 3 26  ? -92.347  13.161  -31.009 1.00 85.34  ? 26  GLY H O   1 
ATOM 2309 N N   . GLY C 3 27  ? -91.834  14.228  -32.922 1.00 79.58  ? 27  GLY H N   1 
ATOM 2310 C CA  . GLY C 3 27  ? -90.991  15.200  -32.252 1.00 84.11  ? 27  GLY H CA  1 
ATOM 2311 C C   . GLY C 3 27  ? -90.740  16.409  -33.121 1.00 82.44  ? 27  GLY H C   1 
ATOM 2312 O O   . GLY C 3 27  ? -90.907  16.370  -34.344 1.00 81.76  ? 27  GLY H O   1 
ATOM 2313 N N   . THR C 3 28  ? -90.327  17.491  -32.468 1.00 90.38  ? 28  THR H N   1 
ATOM 2314 C CA  . THR C 3 28  ? -90.058  18.756  -33.133 1.00 76.98  ? 28  THR H CA  1 
ATOM 2315 C C   . THR C 3 28  ? -88.632  18.782  -33.672 1.00 82.27  ? 28  THR H C   1 
ATOM 2316 O O   . THR C 3 28  ? -87.723  18.165  -33.109 1.00 74.65  ? 28  THR H O   1 
ATOM 2317 C CB  . THR C 3 28  ? -90.269  19.926  -32.170 1.00 81.21  ? 28  THR H CB  1 
ATOM 2318 O OG1 . THR C 3 28  ? -91.435  19.684  -31.374 1.00 120.64 ? 28  THR H OG1 1 
ATOM 2319 C CG2 . THR C 3 28  ? -90.459  21.226  -32.936 1.00 83.11  ? 28  THR H CG2 1 
ATOM 2320 N N   . LEU C 3 29  ? -88.446  19.504  -34.780 1.00 83.71  ? 29  LEU H N   1 
ATOM 2321 C CA  . LEU C 3 29  ? -87.114  19.654  -35.357 1.00 67.24  ? 29  LEU H CA  1 
ATOM 2322 C C   . LEU C 3 29  ? -86.177  20.385  -34.403 1.00 72.59  ? 29  LEU H C   1 
ATOM 2323 O O   . LEU C 3 29  ? -84.985  20.063  -34.322 1.00 62.94  ? 29  LEU H O   1 
ATOM 2324 C CB  . LEU C 3 29  ? -87.206  20.392  -36.692 1.00 80.11  ? 29  LEU H CB  1 
ATOM 2325 C CG  . LEU C 3 29  ? -86.213  19.980  -37.778 1.00 77.56  ? 29  LEU H CG  1 
ATOM 2326 C CD1 . LEU C 3 29  ? -86.310  18.489  -38.049 1.00 74.00  ? 29  LEU H CD1 1 
ATOM 2327 C CD2 . LEU C 3 29  ? -86.459  20.773  -39.053 1.00 73.64  ? 29  LEU H CD2 1 
ATOM 2328 N N   . ASN C 3 30  ? -86.696  21.381  -33.679 1.00 79.39  ? 30  ASN H N   1 
ATOM 2329 C CA  . ASN C 3 30  ? -85.893  22.107  -32.701 1.00 66.64  ? 30  ASN H CA  1 
ATOM 2330 C C   . ASN C 3 30  ? -85.522  21.248  -31.500 1.00 70.22  ? 30  ASN H C   1 
ATOM 2331 O O   . ASN C 3 30  ? -84.573  21.582  -30.782 1.00 64.51  ? 30  ASN H O   1 
ATOM 2332 C CB  . ASN C 3 30  ? -86.641  23.350  -32.220 1.00 68.85  ? 30  ASN H CB  1 
ATOM 2333 C CG  . ASN C 3 30  ? -86.774  24.402  -33.298 1.00 75.53  ? 30  ASN H CG  1 
ATOM 2334 O OD1 . ASN C 3 30  ? -85.805  24.736  -33.981 1.00 68.77  ? 30  ASN H OD1 1 
ATOM 2335 N ND2 . ASN C 3 30  ? -87.982  24.932  -33.460 1.00 89.58  ? 30  ASN H ND2 1 
ATOM 2336 N N   . ASP C 3 31  ? -86.257  20.168  -31.255 1.00 66.24  ? 31  ASP H N   1 
ATOM 2337 C CA  . ASP C 3 31  ? -85.973  19.277  -30.142 1.00 61.77  ? 31  ASP H CA  1 
ATOM 2338 C C   . ASP C 3 31  ? -85.024  18.145  -30.506 1.00 52.83  ? 31  ASP H C   1 
ATOM 2339 O O   . ASP C 3 31  ? -84.646  17.371  -29.619 1.00 59.58  ? 31  ASP H O   1 
ATOM 2340 C CB  . ASP C 3 31  ? -87.276  18.679  -29.605 1.00 74.77  ? 31  ASP H CB  1 
ATOM 2341 C CG  . ASP C 3 31  ? -87.905  19.526  -28.523 1.00 75.27  ? 31  ASP H CG  1 
ATOM 2342 O OD1 . ASP C 3 31  ? -87.250  20.477  -28.047 1.00 78.07  ? 31  ASP H OD1 1 
ATOM 2343 O OD2 . ASP C 3 31  ? -89.064  19.242  -28.156 1.00 96.14  ? 31  ASP H OD2 1 
ATOM 2344 N N   . TYR C 3 32  ? -84.629  18.020  -31.772 1.00 56.76  ? 32  TYR H N   1 
ATOM 2345 C CA  . TYR C 3 32  ? -83.907  16.835  -32.234 1.00 56.83  ? 32  TYR H CA  1 
ATOM 2346 C C   . TYR C 3 32  ? -82.945  17.202  -33.354 1.00 42.42  ? 32  TYR H C   1 
ATOM 2347 O O   . TYR C 3 32  ? -83.280  17.099  -34.541 1.00 61.36  ? 32  TYR H O   1 
ATOM 2348 C CB  . TYR C 3 32  ? -84.879  15.750  -32.694 1.00 48.37  ? 32  TYR H CB  1 
ATOM 2349 C CG  . TYR C 3 32  ? -85.726  15.182  -31.578 1.00 59.89  ? 32  TYR H CG  1 
ATOM 2350 C CD1 . TYR C 3 32  ? -85.212  14.230  -30.706 1.00 56.73  ? 32  TYR H CD1 1 
ATOM 2351 C CD2 . TYR C 3 32  ? -87.037  15.599  -31.393 1.00 67.97  ? 32  TYR H CD2 1 
ATOM 2352 C CE1 . TYR C 3 32  ? -85.982  13.710  -29.681 1.00 54.35  ? 32  TYR H CE1 1 
ATOM 2353 C CE2 . TYR C 3 32  ? -87.812  15.084  -30.371 1.00 71.99  ? 32  TYR H CE2 1 
ATOM 2354 C CZ  . TYR C 3 32  ? -87.281  14.141  -29.520 1.00 57.77  ? 32  TYR H CZ  1 
ATOM 2355 O OH  . TYR C 3 32  ? -88.054  13.629  -28.504 1.00 65.26  ? 32  TYR H OH  1 
ATOM 2356 N N   . PRO C 3 33  ? -81.726  17.625  -33.015 1.00 45.74  ? 33  PRO H N   1 
ATOM 2357 C CA  . PRO C 3 33  ? -80.712  17.848  -34.054 1.00 48.65  ? 33  PRO H CA  1 
ATOM 2358 C C   . PRO C 3 33  ? -80.411  16.554  -34.795 1.00 57.79  ? 33  PRO H C   1 
ATOM 2359 O O   . PRO C 3 33  ? -80.344  15.479  -34.195 1.00 54.71  ? 33  PRO H O   1 
ATOM 2360 C CB  . PRO C 3 33  ? -79.492  18.343  -33.265 1.00 47.75  ? 33  PRO H CB  1 
ATOM 2361 C CG  . PRO C 3 33  ? -80.037  18.796  -31.947 1.00 52.25  ? 33  PRO H CG  1 
ATOM 2362 C CD  . PRO C 3 33  ? -81.199  17.893  -31.667 1.00 54.83  ? 33  PRO H CD  1 
ATOM 2363 N N   . ILE C 3 34  ? -80.207  16.665  -36.107 1.00 67.79  ? 34  ILE H N   1 
ATOM 2364 C CA  . ILE C 3 34  ? -80.157  15.508  -36.998 1.00 58.61  ? 34  ILE H CA  1 
ATOM 2365 C C   . ILE C 3 34  ? -78.725  15.302  -37.469 1.00 57.43  ? 34  ILE H C   1 
ATOM 2366 O O   . ILE C 3 34  ? -78.112  16.220  -38.025 1.00 62.05  ? 34  ILE H O   1 
ATOM 2367 C CB  . ILE C 3 34  ? -81.098  15.683  -38.203 1.00 55.03  ? 34  ILE H CB  1 
ATOM 2368 C CG1 . ILE C 3 34  ? -82.560  15.715  -37.751 1.00 53.02  ? 34  ILE H CG1 1 
ATOM 2369 C CG2 . ILE C 3 34  ? -80.866  14.574  -39.221 1.00 56.68  ? 34  ILE H CG2 1 
ATOM 2370 C CD1 . ILE C 3 34  ? -83.153  14.352  -37.491 1.00 52.37  ? 34  ILE H CD1 1 
ATOM 2371 N N   . ARG C 3 35  ? -78.202  14.093  -37.274 1.00 54.97  ? 35  ARG H N   1 
ATOM 2372 C CA  . ARG C 3 35  ? -76.860  13.743  -37.717 1.00 58.02  ? 35  ARG H CA  1 
ATOM 2373 C C   . ARG C 3 35  ? -76.945  12.895  -38.981 1.00 58.06  ? 35  ARG H C   1 
ATOM 2374 O O   . ARG C 3 35  ? -77.810  12.023  -39.098 1.00 63.88  ? 35  ARG H O   1 
ATOM 2375 C CB  . ARG C 3 35  ? -76.102  12.978  -36.628 1.00 56.92  ? 35  ARG H CB  1 
ATOM 2376 C CG  . ARG C 3 35  ? -76.640  13.172  -35.217 1.00 54.78  ? 35  ARG H CG  1 
ATOM 2377 C CD  . ARG C 3 35  ? -76.447  14.594  -34.720 1.00 68.26  ? 35  ARG H CD  1 
ATOM 2378 N NE  . ARG C 3 35  ? -77.251  14.889  -33.539 1.00 57.14  ? 35  ARG H NE  1 
ATOM 2379 C CZ  . ARG C 3 35  ? -77.024  14.386  -32.333 1.00 60.79  ? 35  ARG H CZ  1 
ATOM 2380 N NH1 . ARG C 3 35  ? -76.009  13.569  -32.105 1.00 67.00  ? 35  ARG H NH1 1 
ATOM 2381 N NH2 . ARG C 3 35  ? -77.825  14.725  -31.327 1.00 71.63  ? 35  ARG H NH2 1 
ATOM 2382 N N   . TRP C 3 36  ? -76.051  13.160  -39.928 1.00 60.27  ? 36  TRP H N   1 
ATOM 2383 C CA  . TRP C 3 36  ? -75.993  12.443  -41.196 1.00 65.83  ? 36  TRP H CA  1 
ATOM 2384 C C   . TRP C 3 36  ? -74.747  11.567  -41.214 1.00 60.69  ? 36  TRP H C   1 
ATOM 2385 O O   . TRP C 3 36  ? -73.622  12.076  -41.096 1.00 65.91  ? 36  TRP H O   1 
ATOM 2386 C CB  . TRP C 3 36  ? -75.994  13.418  -42.375 1.00 60.08  ? 36  TRP H CB  1 
ATOM 2387 C CG  . TRP C 3 36  ? -77.334  14.035  -42.624 1.00 56.80  ? 36  TRP H CG  1 
ATOM 2388 C CD1 . TRP C 3 36  ? -77.751  15.276  -42.239 1.00 59.35  ? 36  TRP H CD1 1 
ATOM 2389 C CD2 . TRP C 3 36  ? -78.440  13.434  -43.308 1.00 67.79  ? 36  TRP H CD2 1 
ATOM 2390 N NE1 . TRP C 3 36  ? -79.048  15.486  -42.641 1.00 61.51  ? 36  TRP H NE1 1 
ATOM 2391 C CE2 . TRP C 3 36  ? -79.494  14.370  -43.300 1.00 66.29  ? 36  TRP H CE2 1 
ATOM 2392 C CE3 . TRP C 3 36  ? -78.640  12.197  -43.929 1.00 69.46  ? 36  TRP H CE3 1 
ATOM 2393 C CZ2 . TRP C 3 36  ? -80.730  14.108  -43.888 1.00 74.40  ? 36  TRP H CZ2 1 
ATOM 2394 C CZ3 . TRP C 3 36  ? -79.869  11.938  -44.515 1.00 65.28  ? 36  TRP H CZ3 1 
ATOM 2395 C CH2 . TRP C 3 36  ? -80.898  12.889  -44.489 1.00 78.06  ? 36  TRP H CH2 1 
ATOM 2396 N N   . VAL C 3 37  ? -74.959  10.256  -41.368 1.00 56.03  ? 37  VAL H N   1 
ATOM 2397 C CA  . VAL C 3 37  ? -73.907  9.249   -41.380 1.00 65.66  ? 37  VAL H CA  1 
ATOM 2398 C C   . VAL C 3 37  ? -74.069  8.430   -42.654 1.00 66.68  ? 37  VAL H C   1 
ATOM 2399 O O   . VAL C 3 37  ? -75.138  8.396   -43.263 1.00 61.91  ? 37  VAL H O   1 
ATOM 2400 C CB  . VAL C 3 37  ? -73.968  8.330   -40.134 1.00 64.37  ? 37  VAL H CB  1 
ATOM 2401 C CG1 . VAL C 3 37  ? -72.669  7.559   -39.950 1.00 63.63  ? 37  VAL H CG1 1 
ATOM 2402 C CG2 . VAL C 3 37  ? -74.298  9.134   -38.883 1.00 70.01  ? 37  VAL H CG2 1 
ATOM 2403 N N   . ARG C 3 38  ? -72.992  7.765   -43.064 1.00 64.37  ? 38  ARG H N   1 
ATOM 2404 C CA  . ARG C 3 38  ? -73.063  6.935   -44.258 1.00 73.09  ? 38  ARG H CA  1 
ATOM 2405 C C   . ARG C 3 38  ? -72.148  5.733   -44.106 1.00 78.48  ? 38  ARG H C   1 
ATOM 2406 O O   . ARG C 3 38  ? -71.196  5.742   -43.321 1.00 77.19  ? 38  ARG H O   1 
ATOM 2407 C CB  . ARG C 3 38  ? -72.680  7.715   -45.518 1.00 74.52  ? 38  ARG H CB  1 
ATOM 2408 C CG  . ARG C 3 38  ? -71.182  7.878   -45.716 1.00 74.43  ? 38  ARG H CG  1 
ATOM 2409 C CD  . ARG C 3 38  ? -70.867  8.242   -47.154 1.00 77.96  ? 38  ARG H CD  1 
ATOM 2410 N NE  . ARG C 3 38  ? -69.437  8.408   -47.381 1.00 83.01  ? 38  ARG H NE  1 
ATOM 2411 C CZ  . ARG C 3 38  ? -68.919  9.032   -48.430 1.00 82.39  ? 38  ARG H CZ  1 
ATOM 2412 N NH1 . ARG C 3 38  ? -69.688  9.562   -49.367 1.00 79.56  ? 38  ARG H NH1 1 
ATOM 2413 N NH2 . ARG C 3 38  ? -67.597  9.129   -48.539 1.00 80.48  ? 38  ARG H NH2 1 
ATOM 2414 N N   . GLN C 3 39  ? -72.454  4.690   -44.877 1.00 70.27  ? 39  GLN H N   1 
ATOM 2415 C CA  . GLN C 3 39  ? -71.561  3.542   -44.977 1.00 77.95  ? 39  GLN H CA  1 
ATOM 2416 C C   . GLN C 3 39  ? -71.602  2.977   -46.388 1.00 89.68  ? 39  GLN H C   1 
ATOM 2417 O O   . GLN C 3 39  ? -72.681  2.769   -46.953 1.00 83.46  ? 39  GLN H O   1 
ATOM 2418 C CB  . GLN C 3 39  ? -71.911  2.456   -43.949 1.00 67.69  ? 39  GLN H CB  1 
ATOM 2419 C CG  . GLN C 3 39  ? -73.246  1.756   -44.153 1.00 63.87  ? 39  GLN H CG  1 
ATOM 2420 C CD  . GLN C 3 39  ? -73.416  0.563   -43.230 1.00 76.28  ? 39  GLN H CD  1 
ATOM 2421 O OE1 . GLN C 3 39  ? -74.525  0.066   -43.034 1.00 71.19  ? 39  GLN H OE1 1 
ATOM 2422 N NE2 . GLN C 3 39  ? -72.309  0.089   -42.668 1.00 78.21  ? 39  GLN H NE2 1 
ATOM 2423 N N   . ALA C 3 40  ? -70.420  2.759   -46.958 1.00 90.80  ? 40  ALA H N   1 
ATOM 2424 C CA  . ALA C 3 40  ? -70.314  2.042   -48.214 1.00 76.43  ? 40  ALA H CA  1 
ATOM 2425 C C   . ALA C 3 40  ? -70.644  0.567   -47.991 1.00 94.61  ? 40  ALA H C   1 
ATOM 2426 O O   . ALA C 3 40  ? -70.475  0.050   -46.883 1.00 112.35 ? 40  ALA H O   1 
ATOM 2427 C CB  . ALA C 3 40  ? -68.909  2.186   -48.792 1.00 68.02  ? 40  ALA H CB  1 
ATOM 2428 N N   . PRO C 3 41  ? -71.137  -0.128  -49.017 1.00 101.55 ? 41  PRO H N   1 
ATOM 2429 C CA  . PRO C 3 41  ? -71.435  -1.558  -48.854 1.00 105.42 ? 41  PRO H CA  1 
ATOM 2430 C C   . PRO C 3 41  ? -70.198  -2.336  -48.423 1.00 102.08 ? 41  PRO H C   1 
ATOM 2431 O O   . PRO C 3 41  ? -69.121  -2.204  -49.009 1.00 88.36  ? 41  PRO H O   1 
ATOM 2432 C CB  . PRO C 3 41  ? -71.922  -1.981  -50.247 1.00 105.41 ? 41  PRO H CB  1 
ATOM 2433 C CG  . PRO C 3 41  ? -71.484  -0.883  -51.174 1.00 90.51  ? 41  PRO H CG  1 
ATOM 2434 C CD  . PRO C 3 41  ? -71.517  0.362   -50.352 1.00 93.97  ? 41  PRO H CD  1 
ATOM 2435 N N   . GLY C 3 42  ? -70.362  -3.146  -47.377 1.00 112.90 ? 42  GLY H N   1 
ATOM 2436 C CA  . GLY C 3 42  ? -69.290  -3.937  -46.820 1.00 111.12 ? 42  GLY H CA  1 
ATOM 2437 C C   . GLY C 3 42  ? -68.418  -3.212  -45.813 1.00 117.89 ? 42  GLY H C   1 
ATOM 2438 O O   . GLY C 3 42  ? -67.801  -3.860  -44.961 1.00 122.22 ? 42  GLY H O   1 
ATOM 2439 N N   . GLN C 3 43  ? -68.354  -1.885  -45.885 1.00 123.26 ? 43  GLN H N   1 
ATOM 2440 C CA  . GLN C 3 43  ? -67.495  -1.106  -45.007 1.00 111.41 ? 43  GLN H CA  1 
ATOM 2441 C C   . GLN C 3 43  ? -68.263  -0.632  -43.775 1.00 104.64 ? 43  GLN H C   1 
ATOM 2442 O O   . GLN C 3 43  ? -69.478  -0.808  -43.653 1.00 97.21  ? 43  GLN H O   1 
ATOM 2443 C CB  . GLN C 3 43  ? -66.904  0.090   -45.757 1.00 100.08 ? 43  GLN H CB  1 
ATOM 2444 C CG  . GLN C 3 43  ? -66.617  -0.168  -47.229 1.00 113.24 ? 43  GLN H CG  1 
ATOM 2445 C CD  . GLN C 3 43  ? -65.724  -1.373  -47.453 1.00 114.57 ? 43  GLN H CD  1 
ATOM 2446 O OE1 . GLN C 3 43  ? -64.779  -1.611  -46.700 1.00 113.68 ? 43  GLN H OE1 1 
ATOM 2447 N NE2 . GLN C 3 43  ? -66.025  -2.146  -48.490 1.00 104.45 ? 43  GLN H NE2 1 
ATOM 2448 N N   . GLY C 3 44  ? -67.528  -0.022  -42.848 1.00 100.48 ? 44  GLY H N   1 
ATOM 2449 C CA  . GLY C 3 44  ? -68.117  0.506   -41.639 1.00 89.24  ? 44  GLY H CA  1 
ATOM 2450 C C   . GLY C 3 44  ? -68.766  1.860   -41.851 1.00 90.65  ? 44  GLY H C   1 
ATOM 2451 O O   . GLY C 3 44  ? -68.726  2.451   -42.930 1.00 102.55 ? 44  GLY H O   1 
ATOM 2452 N N   . LEU C 3 45  ? -69.382  2.355   -40.782 1.00 81.47  ? 45  LEU H N   1 
ATOM 2453 C CA  . LEU C 3 45  ? -70.051  3.645   -40.827 1.00 62.90  ? 45  LEU H CA  1 
ATOM 2454 C C   . LEU C 3 45  ? -69.030  4.780   -40.906 1.00 69.59  ? 45  LEU H C   1 
ATOM 2455 O O   . LEU C 3 45  ? -67.871  4.642   -40.504 1.00 70.31  ? 45  LEU H O   1 
ATOM 2456 C CB  . LEU C 3 45  ? -70.948  3.817   -39.601 1.00 72.55  ? 45  LEU H CB  1 
ATOM 2457 C CG  . LEU C 3 45  ? -72.106  2.824   -39.493 1.00 63.59  ? 45  LEU H CG  1 
ATOM 2458 C CD1 . LEU C 3 45  ? -72.730  2.873   -38.106 1.00 73.46  ? 45  LEU H CD1 1 
ATOM 2459 C CD2 . LEU C 3 45  ? -73.150  3.123   -40.552 1.00 41.66  ? 45  LEU H CD2 1 
ATOM 2460 N N   . GLU C 3 46  ? -69.479  5.914   -41.443 1.00 72.88  ? 46  GLU H N   1 
ATOM 2461 C CA  . GLU C 3 46  ? -68.635  7.095   -41.605 1.00 58.66  ? 46  GLU H CA  1 
ATOM 2462 C C   . GLU C 3 46  ? -69.439  8.335   -41.245 1.00 70.32  ? 46  GLU H C   1 
ATOM 2463 O O   . GLU C 3 46  ? -70.442  8.638   -41.900 1.00 65.73  ? 46  GLU H O   1 
ATOM 2464 C CB  . GLU C 3 46  ? -68.103  7.195   -43.036 1.00 78.77  ? 46  GLU H CB  1 
ATOM 2465 C CG  . GLU C 3 46  ? -67.193  8.381   -43.290 1.00 80.24  ? 46  GLU H CG  1 
ATOM 2466 C CD  . GLU C 3 46  ? -66.705  8.431   -44.726 1.00 101.89 ? 46  GLU H CD  1 
ATOM 2467 O OE1 . GLU C 3 46  ? -67.439  7.955   -45.621 1.00 88.42  ? 46  GLU H OE1 1 
ATOM 2468 O OE2 . GLU C 3 46  ? -65.588  8.941   -44.958 1.00 108.35 ? 46  GLU H OE2 1 
ATOM 2469 N N   . TRP C 3 47  ? -68.996  9.050   -40.212 1.00 59.56  ? 47  TRP H N   1 
ATOM 2470 C CA  . TRP C 3 47  ? -69.680  10.260  -39.768 1.00 62.68  ? 47  TRP H CA  1 
ATOM 2471 C C   . TRP C 3 47  ? -69.517  11.363  -40.806 1.00 62.47  ? 47  TRP H C   1 
ATOM 2472 O O   . TRP C 3 47  ? -68.393  11.778  -41.109 1.00 66.92  ? 47  TRP H O   1 
ATOM 2473 C CB  . TRP C 3 47  ? -69.122  10.715  -38.423 1.00 76.54  ? 47  TRP H CB  1 
ATOM 2474 C CG  . TRP C 3 47  ? -70.015  11.649  -37.662 1.00 65.50  ? 47  TRP H CG  1 
ATOM 2475 C CD1 . TRP C 3 47  ? -70.105  13.003  -37.813 1.00 66.46  ? 47  TRP H CD1 1 
ATOM 2476 C CD2 . TRP C 3 47  ? -70.927  11.302  -36.613 1.00 72.74  ? 47  TRP H CD2 1 
ATOM 2477 N NE1 . TRP C 3 47  ? -71.027  13.518  -36.933 1.00 67.62  ? 47  TRP H NE1 1 
ATOM 2478 C CE2 . TRP C 3 47  ? -71.545  12.494  -36.185 1.00 70.24  ? 47  TRP H CE2 1 
ATOM 2479 C CE3 . TRP C 3 47  ? -71.285  10.098  -35.999 1.00 66.10  ? 47  TRP H CE3 1 
ATOM 2480 C CZ2 . TRP C 3 47  ? -72.499  12.516  -35.170 1.00 70.66  ? 47  TRP H CZ2 1 
ATOM 2481 C CZ3 . TRP C 3 47  ? -72.234  10.122  -34.993 1.00 65.50  ? 47  TRP H CZ3 1 
ATOM 2482 C CH2 . TRP C 3 47  ? -72.829  11.323  -34.588 1.00 66.09  ? 47  TRP H CH2 1 
ATOM 2483 N N   . MET C 3 48  ? -70.636  11.847  -41.344 1.00 57.84  ? 48  MET H N   1 
ATOM 2484 C CA  . MET C 3 48  ? -70.584  12.912  -42.342 1.00 76.29  ? 48  MET H CA  1 
ATOM 2485 C C   . MET C 3 48  ? -70.753  14.291  -41.711 1.00 78.45  ? 48  MET H C   1 
ATOM 2486 O O   . MET C 3 48  ? -69.882  15.156  -41.853 1.00 66.68  ? 48  MET H O   1 
ATOM 2487 C CB  . MET C 3 48  ? -71.654  12.689  -43.414 1.00 71.36  ? 48  MET H CB  1 
ATOM 2488 C CG  . MET C 3 48  ? -71.253  11.726  -44.502 1.00 57.88  ? 48  MET H CG  1 
ATOM 2489 S SD  . MET C 3 48  ? -72.507  11.683  -45.784 1.00 87.56  ? 48  MET H SD  1 
ATOM 2490 C CE  . MET C 3 48  ? -73.994  11.619  -44.794 1.00 53.62  ? 48  MET H CE  1 
ATOM 2491 N N   . GLY C 3 49  ? -71.866  14.514  -41.024 1.00 79.73  ? 49  GLY H N   1 
ATOM 2492 C CA  . GLY C 3 49  ? -72.083  15.831  -40.458 1.00 67.84  ? 49  GLY H CA  1 
ATOM 2493 C C   . GLY C 3 49  ? -73.329  15.885  -39.606 1.00 58.04  ? 49  GLY H C   1 
ATOM 2494 O O   . GLY C 3 49  ? -73.886  14.858  -39.223 1.00 65.55  ? 49  GLY H O   1 
ATOM 2495 N N   . GLY C 3 50  ? -73.764  17.107  -39.312 1.00 61.72  ? 50  GLY H N   1 
ATOM 2496 C CA  . GLY C 3 50  ? -74.949  17.276  -38.492 1.00 63.80  ? 50  GLY H CA  1 
ATOM 2497 C C   . GLY C 3 50  ? -75.524  18.669  -38.587 1.00 46.47  ? 50  GLY H C   1 
ATOM 2498 O O   . GLY C 3 50  ? -74.838  19.627  -38.956 1.00 52.60  ? 50  GLY H O   1 
ATOM 2499 N N   . ILE C 3 51  ? -76.805  18.773  -38.244 1.00 44.12  ? 51  ILE H N   1 
ATOM 2500 C CA  . ILE C 3 51  ? -77.539  20.030  -38.298 1.00 52.76  ? 51  ILE H CA  1 
ATOM 2501 C C   . ILE C 3 51  ? -78.274  20.230  -36.977 1.00 67.40  ? 51  ILE H C   1 
ATOM 2502 O O   . ILE C 3 51  ? -78.909  19.299  -36.463 1.00 70.20  ? 51  ILE H O   1 
ATOM 2503 C CB  . ILE C 3 51  ? -78.521  20.066  -39.486 1.00 59.55  ? 51  ILE H CB  1 
ATOM 2504 C CG1 . ILE C 3 51  ? -79.284  21.391  -39.517 1.00 66.16  ? 51  ILE H CG1 1 
ATOM 2505 C CG2 . ILE C 3 51  ? -79.491  18.887  -39.434 1.00 60.21  ? 51  ILE H CG2 1 
ATOM 2506 C CD1 . ILE C 3 51  ? -80.060  21.610  -40.789 1.00 63.13  ? 51  ILE H CD1 1 
ATOM 2507 N N   . ILE C 3 52  ? -78.171  21.437  -36.426 1.00 54.98  ? 52  ILE H N   1 
ATOM 2508 C CA  . ILE C 3 52  ? -78.897  21.842  -35.227 1.00 62.76  ? 52  ILE H CA  1 
ATOM 2509 C C   . ILE C 3 52  ? -79.864  22.947  -35.640 1.00 56.81  ? 52  ILE H C   1 
ATOM 2510 O O   . ILE C 3 52  ? -79.483  24.131  -35.678 1.00 55.63  ? 52  ILE H O   1 
ATOM 2511 C CB  . ILE C 3 52  ? -77.942  22.309  -34.115 1.00 58.47  ? 52  ILE H CB  1 
ATOM 2512 C CG1 . ILE C 3 52  ? -76.787  21.320  -33.942 1.00 49.85  ? 52  ILE H CG1 1 
ATOM 2513 C CG2 . ILE C 3 52  ? -78.686  22.479  -32.802 1.00 57.73  ? 52  ILE H CG2 1 
ATOM 2514 C CD1 . ILE C 3 52  ? -75.685  21.827  -33.035 1.00 58.77  ? 52  ILE H CD1 1 
ATOM 2515 N N   . PRO C 3 53  ? -81.109  22.598  -35.985 1.00 63.76  ? 53  PRO H N   1 
ATOM 2516 C CA  . PRO C 3 53  ? -82.064  23.626  -36.437 1.00 60.18  ? 53  PRO H CA  1 
ATOM 2517 C C   . PRO C 3 53  ? -82.349  24.703  -35.406 1.00 60.78  ? 53  PRO H C   1 
ATOM 2518 O O   . PRO C 3 53  ? -82.524  25.870  -35.779 1.00 61.32  ? 53  PRO H O   1 
ATOM 2519 C CB  . PRO C 3 53  ? -83.323  22.806  -36.757 1.00 53.76  ? 53  PRO H CB  1 
ATOM 2520 C CG  . PRO C 3 53  ? -82.809  21.444  -37.076 1.00 59.01  ? 53  PRO H CG  1 
ATOM 2521 C CD  . PRO C 3 53  ? -81.642  21.236  -36.151 1.00 68.88  ? 53  PRO H CD  1 
ATOM 2522 N N   . ILE C 3 54  ? -82.399  24.352  -34.118 1.00 66.90  ? 54  ILE H N   1 
ATOM 2523 C CA  . ILE C 3 54  ? -82.793  25.330  -33.106 1.00 59.57  ? 54  ILE H CA  1 
ATOM 2524 C C   . ILE C 3 54  ? -81.772  26.456  -33.013 1.00 53.16  ? 54  ILE H C   1 
ATOM 2525 O O   . ILE C 3 54  ? -82.121  27.592  -32.671 1.00 58.20  ? 54  ILE H O   1 
ATOM 2526 C CB  . ILE C 3 54  ? -83.022  24.641  -31.746 1.00 60.65  ? 54  ILE H CB  1 
ATOM 2527 C CG1 . ILE C 3 54  ? -83.849  25.538  -30.826 1.00 40.34  ? 54  ILE H CG1 1 
ATOM 2528 C CG2 . ILE C 3 54  ? -81.703  24.277  -31.083 1.00 54.12  ? 54  ILE H CG2 1 
ATOM 2529 C CD1 . ILE C 3 54  ? -84.394  24.819  -29.615 1.00 73.57  ? 54  ILE H CD1 1 
ATOM 2530 N N   . LEU C 3 55  ? -80.507  26.170  -33.309 1.00 61.24  ? 55  LEU H N   1 
ATOM 2531 C CA  . LEU C 3 55  ? -79.493  27.202  -33.451 1.00 53.09  ? 55  LEU H CA  1 
ATOM 2532 C C   . LEU C 3 55  ? -79.358  27.683  -34.886 1.00 68.26  ? 55  LEU H C   1 
ATOM 2533 O O   . LEU C 3 55  ? -78.606  28.631  -35.139 1.00 66.77  ? 55  LEU H O   1 
ATOM 2534 C CB  . LEU C 3 55  ? -78.135  26.684  -32.959 1.00 59.96  ? 55  LEU H CB  1 
ATOM 2535 C CG  . LEU C 3 55  ? -78.004  26.425  -31.456 1.00 47.10  ? 55  LEU H CG  1 
ATOM 2536 C CD1 . LEU C 3 55  ? -76.675  25.759  -31.139 1.00 51.29  ? 55  LEU H CD1 1 
ATOM 2537 C CD2 . LEU C 3 55  ? -78.150  27.720  -30.682 1.00 52.42  ? 55  LEU H CD2 1 
ATOM 2538 N N   . GLY C 3 56  ? -80.070  27.059  -35.819 1.00 68.56  ? 56  GLY H N   1 
ATOM 2539 C CA  . GLY C 3 56  ? -79.907  27.380  -37.226 1.00 72.70  ? 56  GLY H CA  1 
ATOM 2540 C C   . GLY C 3 56  ? -78.495  27.153  -37.717 1.00 62.29  ? 56  GLY H C   1 
ATOM 2541 O O   . GLY C 3 56  ? -77.984  27.947  -38.515 1.00 66.04  ? 56  GLY H O   1 
ATOM 2542 N N   . THR C 3 57  ? -77.843  26.090  -37.247 1.00 66.19  ? 57  THR H N   1 
ATOM 2543 C CA  . THR C 3 57  ? -76.441  25.860  -37.568 1.00 57.56  ? 57  THR H CA  1 
ATOM 2544 C C   . THR C 3 57  ? -76.256  24.462  -38.138 1.00 67.04  ? 57  THR H C   1 
ATOM 2545 O O   . THR C 3 57  ? -77.117  23.591  -38.001 1.00 64.11  ? 57  THR H O   1 
ATOM 2546 C CB  . THR C 3 57  ? -75.532  26.039  -36.342 1.00 66.61  ? 57  THR H CB  1 
ATOM 2547 O OG1 . THR C 3 57  ? -75.910  25.108  -35.320 1.00 80.20  ? 57  THR H OG1 1 
ATOM 2548 C CG2 . THR C 3 57  ? -75.630  27.457  -35.802 1.00 73.81  ? 57  THR H CG2 1 
ATOM 2549 N N   . SER C 3 58  ? -75.113  24.260  -38.787 1.00 65.21  ? 58  SER H N   1 
ATOM 2550 C CA  . SER C 3 58  ? -74.777  22.965  -39.353 1.00 54.23  ? 58  SER H CA  1 
ATOM 2551 C C   . SER C 3 58  ? -73.263  22.837  -39.417 1.00 59.68  ? 58  SER H C   1 
ATOM 2552 O O   . SER C 3 58  ? -72.534  23.831  -39.389 1.00 70.99  ? 58  SER H O   1 
ATOM 2553 C CB  . SER C 3 58  ? -75.401  22.781  -40.740 1.00 61.63  ? 58  SER H CB  1 
ATOM 2554 O OG  . SER C 3 58  ? -75.164  23.916  -41.553 1.00 86.24  ? 58  SER H OG  1 
ATOM 2555 N N   . TYR C 3 59  ? -72.797  21.594  -39.496 1.00 67.03  ? 59  TYR H N   1 
ATOM 2556 C CA  . TYR C 3 59  ? -71.372  21.318  -39.578 1.00 65.62  ? 59  TYR H CA  1 
ATOM 2557 C C   . TYR C 3 59  ? -71.162  20.046  -40.383 1.00 54.55  ? 59  TYR H C   1 
ATOM 2558 O O   . TYR C 3 59  ? -72.051  19.191  -40.472 1.00 54.27  ? 59  TYR H O   1 
ATOM 2559 C CB  . TYR C 3 59  ? -70.743  21.177  -38.185 1.00 64.40  ? 59  TYR H CB  1 
ATOM 2560 C CG  . TYR C 3 59  ? -70.952  19.816  -37.563 1.00 61.86  ? 59  TYR H CG  1 
ATOM 2561 C CD1 . TYR C 3 59  ? -72.178  19.467  -37.014 1.00 56.44  ? 59  TYR H CD1 1 
ATOM 2562 C CD2 . TYR C 3 59  ? -69.925  18.881  -37.519 1.00 64.46  ? 59  TYR H CD2 1 
ATOM 2563 C CE1 . TYR C 3 59  ? -72.380  18.227  -36.448 1.00 58.76  ? 59  TYR H CE1 1 
ATOM 2564 C CE2 . TYR C 3 59  ? -70.118  17.635  -36.952 1.00 64.54  ? 59  TYR H CE2 1 
ATOM 2565 C CZ  . TYR C 3 59  ? -71.350  17.315  -36.416 1.00 65.29  ? 59  TYR H CZ  1 
ATOM 2566 O OH  . TYR C 3 59  ? -71.559  16.079  -35.846 1.00 67.11  ? 59  TYR H OH  1 
ATOM 2567 N N   . GLU C 3 60  ? -69.974  19.933  -40.971 1.00 56.29  ? 60  GLU H N   1 
ATOM 2568 C CA  . GLU C 3 60  ? -69.572  18.746  -41.708 1.00 73.96  ? 60  GLU H CA  1 
ATOM 2569 C C   . GLU C 3 60  ? -68.139  18.401  -41.332 1.00 74.70  ? 60  GLU H C   1 
ATOM 2570 O O   . GLU C 3 60  ? -67.360  19.273  -40.934 1.00 78.98  ? 60  GLU H O   1 
ATOM 2571 C CB  . GLU C 3 60  ? -69.678  18.945  -43.232 1.00 72.45  ? 60  GLU H CB  1 
ATOM 2572 C CG  . GLU C 3 60  ? -71.052  19.382  -43.745 1.00 70.56  ? 60  GLU H CG  1 
ATOM 2573 C CD  . GLU C 3 60  ? -71.278  20.881  -43.628 1.00 73.97  ? 60  GLU H CD  1 
ATOM 2574 O OE1 . GLU C 3 60  ? -70.289  21.641  -43.707 1.00 70.53  ? 60  GLU H OE1 1 
ATOM 2575 O OE2 . GLU C 3 60  ? -72.446  21.301  -43.472 1.00 74.91  ? 60  GLU H OE2 1 
ATOM 2576 N N   . THR C 3 61  ? -67.795  17.122  -41.459 1.00 72.24  ? 61  THR H N   1 
ATOM 2577 C CA  . THR C 3 61  ? -66.423  16.706  -41.221 1.00 85.88  ? 61  THR H CA  1 
ATOM 2578 C C   . THR C 3 61  ? -65.513  17.249  -42.324 1.00 90.38  ? 61  THR H C   1 
ATOM 2579 O O   . THR C 3 61  ? -65.969  17.733  -43.364 1.00 96.63  ? 61  THR H O   1 
ATOM 2580 C CB  . THR C 3 61  ? -66.326  15.182  -41.138 1.00 81.75  ? 61  THR H CB  1 
ATOM 2581 O OG1 . THR C 3 61  ? -66.697  14.604  -42.396 1.00 97.29  ? 61  THR H OG1 1 
ATOM 2582 C CG2 . THR C 3 61  ? -67.244  14.649  -40.051 1.00 49.40  ? 61  THR H CG2 1 
ATOM 2583 N N   . GLN C 3 62  ? -64.201  17.173  -42.077 1.00 94.01  ? 62  GLN H N   1 
ATOM 2584 C CA  . GLN C 3 62  ? -63.234  17.743  -43.011 1.00 93.98  ? 62  GLN H CA  1 
ATOM 2585 C C   . GLN C 3 62  ? -63.313  17.086  -44.384 1.00 96.25  ? 62  GLN H C   1 
ATOM 2586 O O   . GLN C 3 62  ? -63.085  17.748  -45.403 1.00 98.29  ? 62  GLN H O   1 
ATOM 2587 C CB  . GLN C 3 62  ? -61.820  17.620  -42.440 1.00 94.61  ? 62  GLN H CB  1 
ATOM 2588 C CG  . GLN C 3 62  ? -60.725  18.142  -43.357 1.00 106.83 ? 62  GLN H CG  1 
ATOM 2589 C CD  . GLN C 3 62  ? -59.410  18.360  -42.632 1.00 120.99 ? 62  GLN H CD  1 
ATOM 2590 O OE1 . GLN C 3 62  ? -59.388  18.623  -41.429 1.00 108.77 ? 62  GLN H OE1 1 
ATOM 2591 N NE2 . GLN C 3 62  ? -58.306  18.251  -43.363 1.00 129.68 ? 62  GLN H NE2 1 
ATOM 2592 N N   . LYS C 3 63  ? -63.646  15.796  -44.436 1.00 95.20  ? 63  LYS H N   1 
ATOM 2593 C CA  . LYS C 3 63  ? -63.750  15.090  -45.708 1.00 88.60  ? 63  LYS H CA  1 
ATOM 2594 C C   . LYS C 3 63  ? -64.939  15.542  -46.548 1.00 76.89  ? 63  LYS H C   1 
ATOM 2595 O O   . LYS C 3 63  ? -65.009  15.182  -47.728 1.00 91.32  ? 63  LYS H O   1 
ATOM 2596 C CB  . LYS C 3 63  ? -63.842  13.581  -45.459 1.00 99.26  ? 63  LYS H CB  1 
ATOM 2597 C CG  . LYS C 3 63  ? -63.368  12.718  -46.620 1.00 100.82 ? 63  LYS H CG  1 
ATOM 2598 C CD  . LYS C 3 63  ? -63.714  11.253  -46.398 1.00 102.62 ? 63  LYS H CD  1 
ATOM 2599 C CE  . LYS C 3 63  ? -63.019  10.352  -47.409 1.00 118.64 ? 63  LYS H CE  1 
ATOM 2600 N NZ  . LYS C 3 63  ? -63.269  10.778  -48.815 1.00 111.47 ? 63  LYS H NZ  1 
ATOM 2601 N N   . PHE C 3 64  ? -65.869  16.318  -45.984 1.00 82.22  ? 64  PHE H N   1 
ATOM 2602 C CA  . PHE C 3 64  ? -67.087  16.689  -46.694 1.00 89.35  ? 64  PHE H CA  1 
ATOM 2603 C C   . PHE C 3 64  ? -67.333  18.193  -46.737 1.00 94.80  ? 64  PHE H C   1 
ATOM 2604 O O   . PHE C 3 64  ? -68.398  18.617  -47.205 1.00 82.87  ? 64  PHE H O   1 
ATOM 2605 C CB  . PHE C 3 64  ? -68.301  15.989  -46.073 1.00 86.65  ? 64  PHE H CB  1 
ATOM 2606 C CG  . PHE C 3 64  ? -68.292  14.496  -46.240 1.00 97.53  ? 64  PHE H CG  1 
ATOM 2607 C CD1 . PHE C 3 64  ? -68.872  13.906  -47.351 1.00 94.75  ? 64  PHE H CD1 1 
ATOM 2608 C CD2 . PHE C 3 64  ? -67.698  13.683  -45.289 1.00 98.53  ? 64  PHE H CD2 1 
ATOM 2609 C CE1 . PHE C 3 64  ? -68.865  12.533  -47.505 1.00 87.48  ? 64  PHE H CE1 1 
ATOM 2610 C CE2 . PHE C 3 64  ? -67.686  12.310  -45.440 1.00 94.14  ? 64  PHE H CE2 1 
ATOM 2611 C CZ  . PHE C 3 64  ? -68.270  11.735  -46.550 1.00 77.77  ? 64  PHE H CZ  1 
ATOM 2612 N N   . GLN C 3 65  ? -66.392  19.011  -46.268 1.00 90.60  ? 65  GLN H N   1 
ATOM 2613 C CA  . GLN C 3 65  ? -66.571  20.455  -46.343 1.00 101.56 ? 65  GLN H CA  1 
ATOM 2614 C C   . GLN C 3 65  ? -66.359  20.929  -47.777 1.00 102.01 ? 65  GLN H C   1 
ATOM 2615 O O   . GLN C 3 65  ? -65.358  20.591  -48.417 1.00 106.56 ? 65  GLN H O   1 
ATOM 2616 C CB  . GLN C 3 65  ? -65.614  21.169  -45.387 1.00 104.35 ? 65  GLN H CB  1 
ATOM 2617 C CG  . GLN C 3 65  ? -64.145  20.822  -45.564 1.00 115.67 ? 65  GLN H CG  1 
ATOM 2618 C CD  . GLN C 3 65  ? -63.259  21.509  -44.541 1.00 125.53 ? 65  GLN H CD  1 
ATOM 2619 O OE1 . GLN C 3 65  ? -63.525  21.459  -43.339 1.00 129.14 ? 65  GLN H OE1 1 
ATOM 2620 N NE2 . GLN C 3 65  ? -62.204  22.164  -45.015 1.00 117.67 ? 65  GLN H NE2 1 
ATOM 2621 N N   . GLY C 3 66  ? -67.313  21.708  -48.284 1.00 98.66  ? 66  GLY H N   1 
ATOM 2622 C CA  . GLY C 3 66  ? -67.310  22.160  -49.656 1.00 90.27  ? 66  GLY H CA  1 
ATOM 2623 C C   . GLY C 3 66  ? -68.155  21.321  -50.593 1.00 81.46  ? 66  GLY H C   1 
ATOM 2624 O O   . GLY C 3 66  ? -68.501  21.792  -51.683 1.00 88.74  ? 66  GLY H O   1 
ATOM 2625 N N   . ARG C 3 67  ? -68.502  20.096  -50.195 1.00 82.60  ? 67  ARG H N   1 
ATOM 2626 C CA  . ARG C 3 67  ? -69.346  19.222  -50.994 1.00 74.63  ? 67  ARG H CA  1 
ATOM 2627 C C   . ARG C 3 67  ? -70.677  18.886  -50.341 1.00 87.50  ? 67  ARG H C   1 
ATOM 2628 O O   . ARG C 3 67  ? -71.627  18.553  -51.059 1.00 74.13  ? 67  ARG H O   1 
ATOM 2629 C CB  . ARG C 3 67  ? -68.616  17.906  -51.306 1.00 87.34  ? 67  ARG H CB  1 
ATOM 2630 C CG  . ARG C 3 67  ? -67.189  18.074  -51.801 1.00 100.37 ? 67  ARG H CG  1 
ATOM 2631 C CD  . ARG C 3 67  ? -66.732  16.841  -52.565 1.00 103.75 ? 67  ARG H CD  1 
ATOM 2632 N NE  . ARG C 3 67  ? -66.681  15.660  -51.712 1.00 103.04 ? 67  ARG H NE  1 
ATOM 2633 C CZ  . ARG C 3 67  ? -67.488  14.613  -51.831 1.00 98.57  ? 67  ARG H CZ  1 
ATOM 2634 N NH1 . ARG C 3 67  ? -68.427  14.567  -52.763 1.00 77.73  ? 67  ARG H NH1 1 
ATOM 2635 N NH2 . ARG C 3 67  ? -67.351  13.589  -50.993 1.00 80.92  ? 67  ARG H NH2 1 
ATOM 2636 N N   . LEU C 3 68  ? -70.777  18.962  -49.017 1.00 91.83  ? 68  LEU H N   1 
ATOM 2637 C CA  . LEU C 3 68  ? -71.981  18.585  -48.290 1.00 74.29  ? 68  LEU H CA  1 
ATOM 2638 C C   . LEU C 3 68  ? -72.686  19.836  -47.784 1.00 70.92  ? 68  LEU H C   1 
ATOM 2639 O O   . LEU C 3 68  ? -72.049  20.722  -47.201 1.00 59.16  ? 68  LEU H O   1 
ATOM 2640 C CB  . LEU C 3 68  ? -71.641  17.649  -47.128 1.00 67.30  ? 68  LEU H CB  1 
ATOM 2641 C CG  . LEU C 3 68  ? -72.806  17.088  -46.306 1.00 74.78  ? 68  LEU H CG  1 
ATOM 2642 C CD1 . LEU C 3 68  ? -73.955  16.632  -47.195 1.00 61.17  ? 68  LEU H CD1 1 
ATOM 2643 C CD2 . LEU C 3 68  ? -72.321  15.944  -45.431 1.00 76.38  ? 68  LEU H CD2 1 
ATOM 2644 N N   . THR C 3 69  ? -73.994  19.911  -48.028 1.00 65.32  ? 69  THR H N   1 
ATOM 2645 C CA  . THR C 3 69  ? -74.827  21.026  -47.588 1.00 58.83  ? 69  THR H CA  1 
ATOM 2646 C C   . THR C 3 69  ? -76.021  20.473  -46.827 1.00 77.72  ? 69  THR H C   1 
ATOM 2647 O O   . THR C 3 69  ? -76.787  19.673  -47.373 1.00 79.67  ? 69  THR H O   1 
ATOM 2648 C CB  . THR C 3 69  ? -75.303  21.869  -48.776 1.00 80.27  ? 69  THR H CB  1 
ATOM 2649 O OG1 . THR C 3 69  ? -74.186  22.541  -49.372 1.00 105.18 ? 69  THR H OG1 1 
ATOM 2650 C CG2 . THR C 3 69  ? -76.339  22.894  -48.329 1.00 62.19  ? 69  THR H CG2 1 
ATOM 2651 N N   . LEU C 3 70  ? -76.189  20.908  -45.581 1.00 74.63  ? 70  LEU H N   1 
ATOM 2652 C CA  . LEU C 3 70  ? -77.293  20.474  -44.736 1.00 65.95  ? 70  LEU H CA  1 
ATOM 2653 C C   . LEU C 3 70  ? -78.253  21.637  -44.531 1.00 67.85  ? 70  LEU H C   1 
ATOM 2654 O O   . LEU C 3 70  ? -77.826  22.748  -44.203 1.00 74.55  ? 70  LEU H O   1 
ATOM 2655 C CB  . LEU C 3 70  ? -76.779  19.956  -43.391 1.00 72.02  ? 70  LEU H CB  1 
ATOM 2656 C CG  . LEU C 3 70  ? -75.606  18.976  -43.475 1.00 62.70  ? 70  LEU H CG  1 
ATOM 2657 C CD1 . LEU C 3 70  ? -75.134  18.573  -42.091 1.00 60.03  ? 70  LEU H CD1 1 
ATOM 2658 C CD2 . LEU C 3 70  ? -75.996  17.752  -44.284 1.00 73.82  ? 70  LEU H CD2 1 
ATOM 2659 N N   . THR C 3 71  ? -79.543  21.383  -44.740 1.00 65.25  ? 71  THR H N   1 
ATOM 2660 C CA  . THR C 3 71  ? -80.567  22.411  -44.628 1.00 63.42  ? 71  THR H CA  1 
ATOM 2661 C C   . THR C 3 71  ? -81.770  21.837  -43.895 1.00 68.28  ? 71  THR H C   1 
ATOM 2662 O O   . THR C 3 71  ? -81.969  20.622  -43.844 1.00 69.44  ? 71  THR H O   1 
ATOM 2663 C CB  . THR C 3 71  ? -81.000  22.938  -46.003 1.00 52.52  ? 71  THR H CB  1 
ATOM 2664 O OG1 . THR C 3 71  ? -81.297  21.833  -46.866 1.00 69.39  ? 71  THR H OG1 1 
ATOM 2665 C CG2 . THR C 3 71  ? -79.895  23.776  -46.627 1.00 75.10  ? 71  THR H CG2 1 
ATOM 2666 N N   . ALA C 3 72  ? -82.583  22.728  -43.335 1.00 62.13  ? 72  ALA H N   1 
ATOM 2667 C CA  . ALA C 3 72  ? -83.769  22.330  -42.595 1.00 61.25  ? 72  ALA H CA  1 
ATOM 2668 C C   . ALA C 3 72  ? -84.975  23.121  -43.076 1.00 60.87  ? 72  ALA H C   1 
ATOM 2669 O O   . ALA C 3 72  ? -84.855  24.272  -43.503 1.00 78.95  ? 72  ALA H O   1 
ATOM 2670 C CB  . ALA C 3 72  ? -83.587  22.532  -41.084 1.00 63.78  ? 72  ALA H CB  1 
ATOM 2671 N N   . ASP C 3 73  ? -86.143  22.486  -42.998 1.00 63.74  ? 73  ASP H N   1 
ATOM 2672 C CA  . ASP C 3 73  ? -87.422  23.108  -43.320 1.00 71.09  ? 73  ASP H CA  1 
ATOM 2673 C C   . ASP C 3 73  ? -88.373  22.782  -42.177 1.00 73.08  ? 73  ASP H C   1 
ATOM 2674 O O   . ASP C 3 73  ? -88.825  21.638  -42.049 1.00 71.27  ? 73  ASP H O   1 
ATOM 2675 C CB  . ASP C 3 73  ? -87.961  22.602  -44.659 1.00 89.09  ? 73  ASP H CB  1 
ATOM 2676 C CG  . ASP C 3 73  ? -89.326  23.167  -44.992 1.00 98.81  ? 73  ASP H CG  1 
ATOM 2677 O OD1 . ASP C 3 73  ? -90.310  22.809  -44.310 1.00 95.90  ? 73  ASP H OD1 1 
ATOM 2678 O OD2 . ASP C 3 73  ? -89.416  23.971  -45.945 1.00 98.56  ? 73  ASP H OD2 1 
ATOM 2679 N N   . GLU C 3 74  ? -88.675  23.787  -41.352 1.00 79.16  ? 74  GLU H N   1 
ATOM 2680 C CA  . GLU C 3 74  ? -89.420  23.556  -40.118 1.00 86.20  ? 74  GLU H CA  1 
ATOM 2681 C C   . GLU C 3 74  ? -90.910  23.337  -40.355 1.00 93.79  ? 74  GLU H C   1 
ATOM 2682 O O   . GLU C 3 74  ? -91.534  22.558  -39.625 1.00 88.68  ? 74  GLU H O   1 
ATOM 2683 C CB  . GLU C 3 74  ? -89.214  24.729  -39.158 1.00 91.92  ? 74  GLU H CB  1 
ATOM 2684 C CG  . GLU C 3 74  ? -87.784  24.877  -38.667 1.00 96.74  ? 74  GLU H CG  1 
ATOM 2685 C CD  . GLU C 3 74  ? -87.620  24.491  -37.208 1.00 102.31 ? 74  GLU H CD  1 
ATOM 2686 O OE1 . GLU C 3 74  ? -88.617  24.069  -36.582 1.00 98.79  ? 74  GLU H OE1 1 
ATOM 2687 O OE2 . GLU C 3 74  ? -86.488  24.604  -36.691 1.00 90.04  ? 74  GLU H OE2 1 
ATOM 2688 N N   . LEU C 3 75  ? -91.500  24.009  -41.347 1.00 92.02  ? 75  LEU H N   1 
ATOM 2689 C CA  . LEU C 3 75  ? -92.938  23.872  -41.563 1.00 98.51  ? 75  LEU H CA  1 
ATOM 2690 C C   . LEU C 3 75  ? -93.309  22.479  -42.061 1.00 97.91  ? 75  LEU H C   1 
ATOM 2691 O O   . LEU C 3 75  ? -94.389  21.976  -41.730 1.00 97.15  ? 75  LEU H O   1 
ATOM 2692 C CB  . LEU C 3 75  ? -93.448  24.949  -42.527 1.00 97.72  ? 75  LEU H CB  1 
ATOM 2693 C CG  . LEU C 3 75  ? -92.989  25.032  -43.985 1.00 103.44 ? 75  LEU H CG  1 
ATOM 2694 C CD1 . LEU C 3 75  ? -93.968  25.879  -44.775 1.00 109.20 ? 75  LEU H CD1 1 
ATOM 2695 C CD2 . LEU C 3 75  ? -91.608  25.650  -44.075 1.00 102.36 ? 75  LEU H CD2 1 
ATOM 2696 N N   . THR C 3 76  ? -92.444  21.841  -42.846 1.00 87.20  ? 76  THR H N   1 
ATOM 2697 C CA  . THR C 3 76  ? -92.649  20.455  -43.243 1.00 88.77  ? 76  THR H CA  1 
ATOM 2698 C C   . THR C 3 76  ? -91.926  19.467  -42.335 1.00 94.48  ? 76  THR H C   1 
ATOM 2699 O O   . THR C 3 76  ? -91.997  18.259  -42.583 1.00 92.71  ? 76  THR H O   1 
ATOM 2700 C CB  . THR C 3 76  ? -92.207  20.240  -44.696 1.00 86.60  ? 76  THR H CB  1 
ATOM 2701 O OG1 . THR C 3 76  ? -90.781  20.343  -44.788 1.00 88.74  ? 76  THR H OG1 1 
ATOM 2702 C CG2 . THR C 3 76  ? -92.851  21.274  -45.609 1.00 87.46  ? 76  THR H CG2 1 
ATOM 2703 N N   . SER C 3 77  ? -91.242  19.950  -41.295 1.00 93.43  ? 77  SER H N   1 
ATOM 2704 C CA  . SER C 3 77  ? -90.547  19.103  -40.321 1.00 77.93  ? 77  SER H CA  1 
ATOM 2705 C C   . SER C 3 77  ? -89.563  18.157  -41.006 1.00 81.98  ? 77  SER H C   1 
ATOM 2706 O O   . SER C 3 77  ? -89.545  16.950  -40.758 1.00 89.87  ? 77  SER H O   1 
ATOM 2707 C CB  . SER C 3 77  ? -91.546  18.322  -39.465 1.00 65.00  ? 77  SER H CB  1 
ATOM 2708 O OG  . SER C 3 77  ? -91.886  19.036  -38.291 1.00 94.27  ? 77  SER H OG  1 
ATOM 2709 N N   . THR C 3 78  ? -88.723  18.720  -41.872 1.00 60.69  ? 78  THR H N   1 
ATOM 2710 C CA  . THR C 3 78  ? -87.849  17.923  -42.719 1.00 65.92  ? 78  THR H CA  1 
ATOM 2711 C C   . THR C 3 78  ? -86.430  18.478  -42.690 1.00 71.24  ? 78  THR H C   1 
ATOM 2712 O O   . THR C 3 78  ? -86.213  19.667  -42.452 1.00 76.12  ? 78  THR H O   1 
ATOM 2713 C CB  . THR C 3 78  ? -88.385  17.886  -44.161 1.00 88.46  ? 78  THR H CB  1 
ATOM 2714 O OG1 . THR C 3 78  ? -89.802  17.675  -44.133 1.00 81.93  ? 78  THR H OG1 1 
ATOM 2715 C CG2 . THR C 3 78  ? -87.735  16.767  -44.959 1.00 82.82  ? 78  THR H CG2 1 
ATOM 2716 N N   . VAL C 3 79  ? -85.462  17.595  -42.922 1.00 69.92  ? 79  VAL H N   1 
ATOM 2717 C CA  . VAL C 3 79  ? -84.056  17.957  -43.036 1.00 73.21  ? 79  VAL H CA  1 
ATOM 2718 C C   . VAL C 3 79  ? -83.532  17.368  -44.339 1.00 69.31  ? 79  VAL H C   1 
ATOM 2719 O O   . VAL C 3 79  ? -83.821  16.211  -44.663 1.00 74.65  ? 79  VAL H O   1 
ATOM 2720 C CB  . VAL C 3 79  ? -83.238  17.455  -41.827 1.00 65.91  ? 79  VAL H CB  1 
ATOM 2721 C CG1 . VAL C 3 79  ? -81.742  17.504  -42.115 1.00 57.13  ? 79  VAL H CG1 1 
ATOM 2722 C CG2 . VAL C 3 79  ? -83.567  18.277  -40.588 1.00 63.03  ? 79  VAL H CG2 1 
ATOM 2723 N N   . TYR C 3 80  ? -82.787  18.164  -45.096 1.00 58.93  ? 80  TYR H N   1 
ATOM 2724 C CA  . TYR C 3 80  ? -82.235  17.737  -46.372 1.00 70.02  ? 80  TYR H CA  1 
ATOM 2725 C C   . TYR C 3 80  ? -80.717  17.797  -46.323 1.00 67.90  ? 80  TYR H C   1 
ATOM 2726 O O   . TYR C 3 80  ? -80.137  18.722  -45.745 1.00 81.55  ? 80  TYR H O   1 
ATOM 2727 C CB  . TYR C 3 80  ? -82.757  18.608  -47.528 1.00 73.41  ? 80  TYR H CB  1 
ATOM 2728 C CG  . TYR C 3 80  ? -84.264  18.730  -47.560 1.00 67.87  ? 80  TYR H CG  1 
ATOM 2729 C CD1 . TYR C 3 80  ? -85.044  17.773  -48.195 1.00 72.23  ? 80  TYR H CD1 1 
ATOM 2730 C CD2 . TYR C 3 80  ? -84.906  19.797  -46.948 1.00 73.37  ? 80  TYR H CD2 1 
ATOM 2731 C CE1 . TYR C 3 80  ? -86.423  17.877  -48.221 1.00 78.95  ? 80  TYR H CE1 1 
ATOM 2732 C CE2 . TYR C 3 80  ? -86.282  19.909  -46.967 1.00 80.32  ? 80  TYR H CE2 1 
ATOM 2733 C CZ  . TYR C 3 80  ? -87.037  18.948  -47.605 1.00 82.37  ? 80  TYR H CZ  1 
ATOM 2734 O OH  . TYR C 3 80  ? -88.409  19.058  -47.628 1.00 87.77  ? 80  TYR H OH  1 
ATOM 2735 N N   . MET C 3 81  ? -80.080  16.794  -46.911 1.00 80.01  ? 81  MET H N   1 
ATOM 2736 C CA  . MET C 3 81  ? -78.650  16.828  -47.166 1.00 75.31  ? 81  MET H CA  1 
ATOM 2737 C C   . MET C 3 81  ? -78.432  16.816  -48.671 1.00 77.87  ? 81  MET H C   1 
ATOM 2738 O O   . MET C 3 81  ? -79.245  16.275  -49.424 1.00 80.89  ? 81  MET H O   1 
ATOM 2739 C CB  . MET C 3 81  ? -77.921  15.645  -46.525 1.00 76.07  ? 81  MET H CB  1 
ATOM 2740 C CG  . MET C 3 81  ? -77.996  14.375  -47.347 1.00 85.94  ? 81  MET H CG  1 
ATOM 2741 S SD  . MET C 3 81  ? -76.624  13.260  -47.031 1.00 103.65 ? 81  MET H SD  1 
ATOM 2742 C CE  . MET C 3 81  ? -76.911  12.055  -48.318 1.00 85.59  ? 81  MET H CE  1 
ATOM 2743 N N   . GLU C 3 82  ? -77.346  17.443  -49.110 1.00 73.40  ? 82  GLU H N   1 
ATOM 2744 C CA  . GLU C 3 82  ? -77.022  17.503  -50.530 1.00 74.40  ? 82  GLU H CA  1 
ATOM 2745 C C   . GLU C 3 82  ? -75.526  17.310  -50.704 1.00 86.09  ? 82  GLU H C   1 
ATOM 2746 O O   . GLU C 3 82  ? -74.728  18.096  -50.183 1.00 76.64  ? 82  GLU H O   1 
ATOM 2747 C CB  . GLU C 3 82  ? -77.474  18.828  -51.152 1.00 75.30  ? 82  GLU H CB  1 
ATOM 2748 C CG  . GLU C 3 82  ? -77.346  18.868  -52.667 1.00 101.33 ? 82  GLU H CG  1 
ATOM 2749 C CD  . GLU C 3 82  ? -77.546  20.260  -53.238 1.00 107.58 ? 82  GLU H CD  1 
ATOM 2750 O OE1 . GLU C 3 82  ? -77.436  21.242  -52.473 1.00 112.75 ? 82  GLU H OE1 1 
ATOM 2751 O OE2 . GLU C 3 82  ? -77.802  20.372  -54.456 1.00 101.55 ? 82  GLU H OE2 1 
ATOM 2752 N N   . LEU C 3 83  ? -75.156  16.267  -51.439 1.00 89.13  ? 83  LEU H N   1 
ATOM 2753 C CA  . LEU C 3 83  ? -73.768  15.945  -51.726 1.00 89.42  ? 83  LEU H CA  1 
ATOM 2754 C C   . LEU C 3 83  ? -73.491  16.172  -53.206 1.00 96.32  ? 83  LEU H C   1 
ATOM 2755 O O   . LEU C 3 83  ? -74.289  15.781  -54.066 1.00 89.14  ? 83  LEU H O   1 
ATOM 2756 C CB  . LEU C 3 83  ? -73.445  14.498  -51.337 1.00 71.56  ? 83  LEU H CB  1 
ATOM 2757 C CG  . LEU C 3 83  ? -71.959  14.134  -51.291 1.00 85.06  ? 83  LEU H CG  1 
ATOM 2758 C CD1 . LEU C 3 83  ? -71.183  15.138  -50.453 1.00 77.20  ? 83  LEU H CD1 1 
ATOM 2759 C CD2 . LEU C 3 83  ? -71.763  12.724  -50.760 1.00 84.42  ? 83  LEU H CD2 1 
ATOM 2760 N N   . ARG C 3 84  ? -72.359  16.811  -53.493 1.00 94.48  ? 84  ARG H N   1 
ATOM 2761 C CA  . ARG C 3 84  ? -71.993  17.234  -54.837 1.00 101.66 ? 84  ARG H CA  1 
ATOM 2762 C C   . ARG C 3 84  ? -70.602  16.712  -55.172 1.00 113.27 ? 84  ARG H C   1 
ATOM 2763 O O   . ARG C 3 84  ? -69.850  16.276  -54.295 1.00 106.81 ? 84  ARG H O   1 
ATOM 2764 C CB  . ARG C 3 84  ? -72.041  18.764  -54.965 1.00 96.99  ? 84  ARG H CB  1 
ATOM 2765 C CG  . ARG C 3 84  ? -73.442  19.345  -54.846 1.00 99.19  ? 84  ARG H CG  1 
ATOM 2766 C CD  . ARG C 3 84  ? -73.467  20.837  -55.128 1.00 100.09 ? 84  ARG H CD  1 
ATOM 2767 N NE  . ARG C 3 84  ? -72.759  21.584  -54.095 1.00 110.18 ? 84  ARG H NE  1 
ATOM 2768 C CZ  . ARG C 3 84  ? -73.284  21.922  -52.925 1.00 121.09 ? 84  ARG H CZ  1 
ATOM 2769 N NH1 . ARG C 3 84  ? -74.525  21.592  -52.603 1.00 105.92 ? 84  ARG H NH1 1 
ATOM 2770 N NH2 . ARG C 3 84  ? -72.544  22.601  -52.053 1.00 114.66 ? 84  ARG H NH2 1 
ATOM 2771 N N   . TYR C 3 85  ? -70.269  16.761  -56.466 1.00 95.23  ? 85  TYR H N   1 
ATOM 2772 C CA  . TYR C 3 85  ? -68.993  16.268  -56.991 1.00 86.62  ? 85  TYR H CA  1 
ATOM 2773 C C   . TYR C 3 85  ? -68.820  14.778  -56.687 1.00 83.65  ? 85  TYR H C   1 
ATOM 2774 O O   . TYR C 3 85  ? -67.817  14.340  -56.120 1.00 76.29  ? 85  TYR H O   1 
ATOM 2775 C CB  . TYR C 3 85  ? -67.815  17.085  -56.444 1.00 101.33 ? 85  TYR H CB  1 
ATOM 2776 C CG  . TYR C 3 85  ? -67.798  18.530  -56.892 1.00 118.81 ? 85  TYR H CG  1 
ATOM 2777 C CD1 . TYR C 3 85  ? -67.977  18.868  -58.228 1.00 109.36 ? 85  TYR H CD1 1 
ATOM 2778 C CD2 . TYR C 3 85  ? -67.608  19.558  -55.976 1.00 122.96 ? 85  TYR H CD2 1 
ATOM 2779 C CE1 . TYR C 3 85  ? -67.962  20.188  -58.640 1.00 109.72 ? 85  TYR H CE1 1 
ATOM 2780 C CE2 . TYR C 3 85  ? -67.593  20.881  -56.378 1.00 126.81 ? 85  TYR H CE2 1 
ATOM 2781 C CZ  . TYR C 3 85  ? -67.770  21.190  -57.711 1.00 124.50 ? 85  TYR H CZ  1 
ATOM 2782 O OH  . TYR C 3 85  ? -67.756  22.505  -58.115 1.00 132.92 ? 85  TYR H OH  1 
ATOM 2783 N N   . LEU C 3 86  ? -69.815  14.000  -57.110 1.00 82.79  ? 86  LEU H N   1 
ATOM 2784 C CA  . LEU C 3 86  ? -69.881  12.587  -56.761 1.00 85.43  ? 86  LEU H CA  1 
ATOM 2785 C C   . LEU C 3 86  ? -68.726  11.800  -57.376 1.00 86.02  ? 86  LEU H C   1 
ATOM 2786 O O   . LEU C 3 86  ? -68.146  12.184  -58.394 1.00 107.92 ? 86  LEU H O   1 
ATOM 2787 C CB  . LEU C 3 86  ? -71.214  11.989  -57.211 1.00 76.88  ? 86  LEU H CB  1 
ATOM 2788 C CG  . LEU C 3 86  ? -72.465  12.520  -56.507 1.00 91.60  ? 86  LEU H CG  1 
ATOM 2789 C CD1 . LEU C 3 86  ? -73.730  12.014  -57.187 1.00 82.23  ? 86  LEU H CD1 1 
ATOM 2790 C CD2 . LEU C 3 86  ? -72.456  12.137  -55.033 1.00 85.79  ? 86  LEU H CD2 1 
ATOM 2791 N N   . THR C 3 87  ? -68.395  10.685  -56.729 1.00 96.31  ? 87  THR H N   1 
ATOM 2792 C CA  . THR C 3 87  ? -67.301  9.812   -57.131 1.00 86.97  ? 87  THR H CA  1 
ATOM 2793 C C   . THR C 3 87  ? -67.720  8.379   -56.830 1.00 99.53  ? 87  THR H C   1 
ATOM 2794 O O   . THR C 3 87  ? -68.674  8.141   -56.086 1.00 101.32 ? 87  THR H O   1 
ATOM 2795 C CB  . THR C 3 87  ? -65.996  10.179  -56.400 1.00 91.13  ? 87  THR H CB  1 
ATOM 2796 O OG1 . THR C 3 87  ? -65.804  11.599  -56.453 1.00 108.64 ? 87  THR H OG1 1 
ATOM 2797 C CG2 . THR C 3 87  ? -64.787  9.506   -57.039 1.00 94.23  ? 87  THR H CG2 1 
ATOM 2798 N N   . SER C 3 88  ? -67.009  7.419   -57.429 1.00 112.49 ? 88  SER H N   1 
ATOM 2799 C CA  . SER C 3 88  ? -67.328  6.011   -57.209 1.00 113.99 ? 88  SER H CA  1 
ATOM 2800 C C   . SER C 3 88  ? -67.306  5.647   -55.728 1.00 111.83 ? 88  SER H C   1 
ATOM 2801 O O   . SER C 3 88  ? -68.038  4.746   -55.302 1.00 120.19 ? 88  SER H O   1 
ATOM 2802 C CB  . SER C 3 88  ? -66.356  5.125   -57.991 1.00 100.19 ? 88  SER H CB  1 
ATOM 2803 O OG  . SER C 3 88  ? -65.013  5.388   -57.622 1.00 109.87 ? 88  SER H OG  1 
ATOM 2804 N N   . GLU C 3 89  ? -66.488  6.334   -54.929 1.00 102.37 ? 89  GLU H N   1 
ATOM 2805 C CA  . GLU C 3 89  ? -66.422  6.109   -53.491 1.00 100.08 ? 89  GLU H CA  1 
ATOM 2806 C C   . GLU C 3 89  ? -67.476  6.900   -52.716 1.00 86.69  ? 89  GLU H C   1 
ATOM 2807 O O   . GLU C 3 89  ? -67.332  7.082   -51.502 1.00 85.23  ? 89  GLU H O   1 
ATOM 2808 C CB  . GLU C 3 89  ? -65.022  6.441   -52.968 1.00 96.42  ? 89  GLU H CB  1 
ATOM 2809 C CG  . GLU C 3 89  ? -64.675  7.919   -53.004 1.00 102.61 ? 89  GLU H CG  1 
ATOM 2810 C CD  . GLU C 3 89  ? -63.313  8.209   -52.405 1.00 117.15 ? 89  GLU H CD  1 
ATOM 2811 O OE1 . GLU C 3 89  ? -62.320  7.611   -52.870 1.00 111.42 ? 89  GLU H OE1 1 
ATOM 2812 O OE2 . GLU C 3 89  ? -63.237  9.036   -51.472 1.00 132.45 ? 89  GLU H OE2 1 
ATOM 2813 N N   . ASP C 3 90  ? -68.524  7.376   -53.389 1.00 91.35  ? 90  ASP H N   1 
ATOM 2814 C CA  . ASP C 3 90  ? -69.627  8.074   -52.739 1.00 77.23  ? 90  ASP H CA  1 
ATOM 2815 C C   . ASP C 3 90  ? -70.951  7.338   -52.900 1.00 83.75  ? 90  ASP H C   1 
ATOM 2816 O O   . ASP C 3 90  ? -72.000  7.881   -52.531 1.00 79.28  ? 90  ASP H O   1 
ATOM 2817 C CB  . ASP C 3 90  ? -69.761  9.500   -53.280 1.00 90.98  ? 90  ASP H CB  1 
ATOM 2818 C CG  . ASP C 3 90  ? -68.691  10.432  -52.746 1.00 100.74 ? 90  ASP H CG  1 
ATOM 2819 O OD1 . ASP C 3 90  ? -68.330  10.310  -51.555 1.00 89.77  ? 90  ASP H OD1 1 
ATOM 2820 O OD2 . ASP C 3 90  ? -68.214  11.289  -53.520 1.00 91.95  ? 90  ASP H OD2 1 
ATOM 2821 N N   . ALA C 3 91  ? -70.936  6.134   -53.465 1.00 92.53  ? 91  ALA H N   1 
ATOM 2822 C CA  . ALA C 3 91  ? -72.124  5.295   -53.540 1.00 88.39  ? 91  ALA H CA  1 
ATOM 2823 C C   . ALA C 3 91  ? -72.201  4.474   -52.260 1.00 91.83  ? 91  ALA H C   1 
ATOM 2824 O O   . ALA C 3 91  ? -71.283  3.703   -51.958 1.00 80.59  ? 91  ALA H O   1 
ATOM 2825 C CB  . ALA C 3 91  ? -72.077  4.388   -54.768 1.00 90.91  ? 91  ALA H CB  1 
ATOM 2826 N N   . ALA C 3 92  ? -73.282  4.642   -51.510 1.00 84.14  ? 92  ALA H N   1 
ATOM 2827 C CA  . ALA C 3 92  ? -73.338  4.106   -50.155 1.00 66.13  ? 92  ALA H CA  1 
ATOM 2828 C C   . ALA C 3 92  ? -74.772  4.207   -49.653 1.00 70.53  ? 92  ALA H C   1 
ATOM 2829 O O   . ALA C 3 92  ? -75.667  4.687   -50.355 1.00 60.19  ? 92  ALA H O   1 
ATOM 2830 C CB  . ALA C 3 92  ? -72.373  4.855   -49.234 1.00 71.98  ? 92  ALA H CB  1 
ATOM 2831 N N   . VAL C 3 93  ? -74.982  3.752   -48.421 1.00 62.03  ? 93  VAL H N   1 
ATOM 2832 C CA  . VAL C 3 93  ? -76.255  3.918   -47.735 1.00 60.59  ? 93  VAL H CA  1 
ATOM 2833 C C   . VAL C 3 93  ? -76.112  5.075   -46.757 1.00 67.93  ? 93  VAL H C   1 
ATOM 2834 O O   . VAL C 3 93  ? -75.144  5.134   -45.984 1.00 73.48  ? 93  VAL H O   1 
ATOM 2835 C CB  . VAL C 3 93  ? -76.681  2.627   -47.017 1.00 71.67  ? 93  VAL H CB  1 
ATOM 2836 C CG1 . VAL C 3 93  ? -78.149  2.712   -46.617 1.00 64.64  ? 93  VAL H CG1 1 
ATOM 2837 C CG2 . VAL C 3 93  ? -76.426  1.418   -47.905 1.00 72.07  ? 93  VAL H CG2 1 
ATOM 2838 N N   . TYR C 3 94  ? -77.065  6.003   -46.807 1.00 63.47  ? 94  TYR H N   1 
ATOM 2839 C CA  . TYR C 3 94  ? -77.040  7.231   -46.026 1.00 69.79  ? 94  TYR H CA  1 
ATOM 2840 C C   . TYR C 3 94  ? -78.146  7.187   -44.982 1.00 70.80  ? 94  TYR H C   1 
ATOM 2841 O O   . TYR C 3 94  ? -79.295  6.858   -45.301 1.00 64.90  ? 94  TYR H O   1 
ATOM 2842 C CB  . TYR C 3 94  ? -77.219  8.452   -46.929 1.00 70.72  ? 94  TYR H CB  1 
ATOM 2843 C CG  . TYR C 3 94  ? -76.037  8.711   -47.830 1.00 83.74  ? 94  TYR H CG  1 
ATOM 2844 C CD1 . TYR C 3 94  ? -74.943  9.431   -47.375 1.00 78.41  ? 94  TYR H CD1 1 
ATOM 2845 C CD2 . TYR C 3 94  ? -76.017  8.248   -49.142 1.00 70.17  ? 94  TYR H CD2 1 
ATOM 2846 C CE1 . TYR C 3 94  ? -73.858  9.677   -48.190 1.00 78.93  ? 94  TYR H CE1 1 
ATOM 2847 C CE2 . TYR C 3 94  ? -74.931  8.490   -49.967 1.00 64.04  ? 94  TYR H CE2 1 
ATOM 2848 C CZ  . TYR C 3 94  ? -73.854  9.205   -49.480 1.00 74.14  ? 94  TYR H CZ  1 
ATOM 2849 O OH  . TYR C 3 94  ? -72.763  9.456   -50.277 1.00 73.40  ? 94  TYR H OH  1 
ATOM 2850 N N   . PHE C 3 95  ? -77.798  7.526   -43.744 1.00 60.38  ? 95  PHE H N   1 
ATOM 2851 C CA  . PHE C 3 95  ? -78.709  7.488   -42.614 1.00 59.20  ? 95  PHE H CA  1 
ATOM 2852 C C   . PHE C 3 95  ? -78.785  8.860   -41.959 1.00 61.71  ? 95  PHE H C   1 
ATOM 2853 O O   . PHE C 3 95  ? -77.772  9.563   -41.839 1.00 52.49  ? 95  PHE H O   1 
ATOM 2854 C CB  . PHE C 3 95  ? -78.254  6.460   -41.571 1.00 64.25  ? 95  PHE H CB  1 
ATOM 2855 C CG  . PHE C 3 95  ? -78.200  5.049   -42.082 1.00 54.56  ? 95  PHE H CG  1 
ATOM 2856 C CD1 . PHE C 3 95  ? -79.344  4.270   -42.121 1.00 53.36  ? 95  PHE H CD1 1 
ATOM 2857 C CD2 . PHE C 3 95  ? -77.002  4.497   -42.507 1.00 41.08  ? 95  PHE H CD2 1 
ATOM 2858 C CE1 . PHE C 3 95  ? -79.299  2.969   -42.582 1.00 44.75  ? 95  PHE H CE1 1 
ATOM 2859 C CE2 . PHE C 3 95  ? -76.950  3.196   -42.971 1.00 49.43  ? 95  PHE H CE2 1 
ATOM 2860 C CZ  . PHE C 3 95  ? -78.100  2.431   -43.007 1.00 56.19  ? 95  PHE H CZ  1 
ATOM 2861 N N   . CYS C 3 96  ? -79.992  9.232   -41.544 1.00 58.89  ? 96  CYS H N   1 
ATOM 2862 C CA  . CYS C 3 96  ? -80.214  10.341  -40.628 1.00 62.28  ? 96  CYS H CA  1 
ATOM 2863 C C   . CYS C 3 96  ? -80.566  9.759   -39.265 1.00 63.51  ? 96  CYS H C   1 
ATOM 2864 O O   . CYS C 3 96  ? -81.369  8.824   -39.177 1.00 67.62  ? 96  CYS H O   1 
ATOM 2865 C CB  . CYS C 3 96  ? -81.327  11.269  -41.125 1.00 61.73  ? 96  CYS H CB  1 
ATOM 2866 S SG  . CYS C 3 96  ? -82.935  10.478  -41.377 1.00 79.76  ? 96  CYS H SG  1 
ATOM 2867 N N   . ALA C 3 97  ? -79.950  10.290  -38.212 1.00 63.03  ? 97  ALA H N   1 
ATOM 2868 C CA  . ALA C 3 97  ? -80.124  9.745   -36.873 1.00 67.65  ? 97  ALA H CA  1 
ATOM 2869 C C   . ALA C 3 97  ? -80.235  10.872  -35.857 1.00 57.06  ? 97  ALA H C   1 
ATOM 2870 O O   . ALA C 3 97  ? -79.883  12.024  -36.127 1.00 54.12  ? 97  ALA H O   1 
ATOM 2871 C CB  . ALA C 3 97  ? -78.975  8.804   -36.491 1.00 61.22  ? 97  ALA H CB  1 
ATOM 2872 N N   . THR C 3 98  ? -80.738  10.521  -34.676 1.00 56.82  ? 98  THR H N   1 
ATOM 2873 C CA  . THR C 3 98  ? -80.953  11.483  -33.602 1.00 61.36  ? 98  THR H CA  1 
ATOM 2874 C C   . THR C 3 98  ? -80.718  10.774  -32.271 1.00 63.76  ? 98  THR H C   1 
ATOM 2875 O O   . THR C 3 98  ? -80.158  9.675   -32.222 1.00 67.05  ? 98  THR H O   1 
ATOM 2876 C CB  . THR C 3 98  ? -82.361  12.086  -33.687 1.00 51.62  ? 98  THR H CB  1 
ATOM 2877 O OG1 . THR C 3 98  ? -82.743  12.222  -35.060 1.00 86.06  ? 98  THR H OG1 1 
ATOM 2878 C CG2 . THR C 3 98  ? -82.385  13.459  -33.056 1.00 45.59  ? 98  THR H CG2 1 
ATOM 2879 N N   . MET C 3 99  ? -81.147  11.413  -31.185 1.00 59.03  ? 99  MET H N   1 
ATOM 2880 C CA  . MET C 3 99  ? -81.044  10.860  -29.846 1.00 53.51  ? 99  MET H CA  1 
ATOM 2881 C C   . MET C 3 99  ? -82.201  11.384  -29.011 1.00 54.51  ? 99  MET H C   1 
ATOM 2882 O O   . MET C 3 99  ? -82.703  12.487  -29.244 1.00 55.01  ? 99  MET H O   1 
ATOM 2883 C CB  . MET C 3 99  ? -79.710  11.223  -29.195 1.00 42.28  ? 99  MET H CB  1 
ATOM 2884 C CG  . MET C 3 99  ? -79.519  12.715  -29.002 1.00 52.26  ? 99  MET H CG  1 
ATOM 2885 S SD  . MET C 3 99  ? -77.931  13.049  -28.243 1.00 76.33  ? 99  MET H SD  1 
ATOM 2886 C CE  . MET C 3 99  ? -76.952  11.829  -29.102 1.00 55.91  ? 99  MET H CE  1 
ATOM 2887 N N   . THR C 3 100 ? -82.608  10.590  -28.024 1.00 55.29  ? 100 THR H N   1 
ATOM 2888 C CA  . THR C 3 100 ? -83.770  10.912  -27.210 1.00 60.10  ? 100 THR H CA  1 
ATOM 2889 C C   . THR C 3 100 ? -83.426  11.594  -25.890 1.00 56.98  ? 100 THR H C   1 
ATOM 2890 O O   . THR C 3 100 ? -84.341  12.062  -25.204 1.00 59.42  ? 100 THR H O   1 
ATOM 2891 C CB  . THR C 3 100 ? -84.578  9.638   -26.927 1.00 69.73  ? 100 THR H CB  1 
ATOM 2892 O OG1 . THR C 3 100 ? -83.790  8.735   -26.140 1.00 71.15  ? 100 THR H OG1 1 
ATOM 2893 C CG2 . THR C 3 100 ? -84.962  8.956   -28.232 1.00 64.73  ? 100 THR H CG2 1 
ATOM 2894 N N   . SER C 3 101 ? -82.150  11.671  -25.517 1.00 49.21  ? 101 SER H N   1 
ATOM 2895 C CA  . SER C 3 101 ? -81.776  12.240  -24.229 1.00 49.55  ? 101 SER H CA  1 
ATOM 2896 C C   . SER C 3 101 ? -80.443  12.962  -24.350 1.00 54.33  ? 101 SER H C   1 
ATOM 2897 O O   . SER C 3 101 ? -79.609  12.585  -25.182 1.00 51.13  ? 101 SER H O   1 
ATOM 2898 C CB  . SER C 3 101 ? -81.689  11.154  -23.147 1.00 54.30  ? 101 SER H CB  1 
ATOM 2899 O OG  . SER C 3 101 ? -80.735  11.498  -22.160 1.00 57.19  ? 101 SER H OG  1 
ATOM 2900 N N   . PRO C 3 102 ? -80.210  13.997  -23.533 1.00 47.98  ? 102 PRO H N   1 
ATOM 2901 C CA  . PRO C 3 102 ? -78.922  14.710  -23.587 1.00 47.98  ? 102 PRO H CA  1 
ATOM 2902 C C   . PRO C 3 102 ? -77.756  13.925  -23.013 1.00 46.73  ? 102 PRO H C   1 
ATOM 2903 O O   . PRO C 3 102 ? -76.609  14.363  -23.166 1.00 51.26  ? 102 PRO H O   1 
ATOM 2904 C CB  . PRO C 3 102 ? -79.185  15.977  -22.759 1.00 33.68  ? 102 PRO H CB  1 
ATOM 2905 C CG  . PRO C 3 102 ? -80.674  16.093  -22.673 1.00 42.08  ? 102 PRO H CG  1 
ATOM 2906 C CD  . PRO C 3 102 ? -81.180  14.686  -22.669 1.00 44.15  ? 102 PRO H CD  1 
ATOM 2907 N N   . VAL C 3 103 ? -78.006  12.802  -22.338 1.00 48.64  ? 103 VAL H N   1 
ATOM 2908 C CA  . VAL C 3 103 ? -76.910  12.010  -21.794 1.00 66.21  ? 103 VAL H CA  1 
ATOM 2909 C C   . VAL C 3 103 ? -76.139  11.286  -22.892 1.00 58.04  ? 103 VAL H C   1 
ATOM 2910 O O   . VAL C 3 103 ? -74.978  10.911  -22.686 1.00 61.09  ? 103 VAL H O   1 
ATOM 2911 C CB  . VAL C 3 103 ? -77.445  11.014  -20.746 1.00 58.12  ? 103 VAL H CB  1 
ATOM 2912 C CG1 . VAL C 3 103 ? -76.309  10.487  -19.879 1.00 56.99  ? 103 VAL H CG1 1 
ATOM 2913 C CG2 . VAL C 3 103 ? -78.508  11.676  -19.886 1.00 47.27  ? 103 VAL H CG2 1 
ATOM 2914 N N   . PHE C 3 104 ? -76.746  11.086  -24.062 1.00 54.55  ? 104 PHE H N   1 
ATOM 2915 C CA  . PHE C 3 104 ? -76.078  10.335  -25.119 1.00 56.03  ? 104 PHE H CA  1 
ATOM 2916 C C   . PHE C 3 104 ? -74.988  11.145  -25.815 1.00 64.18  ? 104 PHE H C   1 
ATOM 2917 O O   . PHE C 3 104 ? -74.037  10.557  -26.341 1.00 67.73  ? 104 PHE H O   1 
ATOM 2918 C CB  . PHE C 3 104 ? -77.105  9.842   -26.137 1.00 51.93  ? 104 PHE H CB  1 
ATOM 2919 C CG  . PHE C 3 104 ? -78.144  8.924   -25.556 1.00 50.93  ? 104 PHE H CG  1 
ATOM 2920 C CD1 . PHE C 3 104 ? -77.837  8.080   -24.503 1.00 64.67  ? 104 PHE H CD1 1 
ATOM 2921 C CD2 . PHE C 3 104 ? -79.436  8.923   -26.051 1.00 61.07  ? 104 PHE H CD2 1 
ATOM 2922 C CE1 . PHE C 3 104 ? -78.799  7.240   -23.968 1.00 76.90  ? 104 PHE H CE1 1 
ATOM 2923 C CE2 . PHE C 3 104 ? -80.401  8.090   -25.518 1.00 38.77  ? 104 PHE H CE2 1 
ATOM 2924 C CZ  . PHE C 3 104 ? -80.082  7.247   -24.480 1.00 55.72  ? 104 PHE H CZ  1 
ATOM 2925 N N   . ILE C 3 105 ? -75.111  12.476  -25.835 1.00 59.46  ? 105 ILE H N   1 
ATOM 2926 C CA  . ILE C 3 105 ? -74.139  13.382  -26.453 1.00 59.50  ? 105 ILE H CA  1 
ATOM 2927 C C   . ILE C 3 105 ? -74.069  13.144  -27.960 1.00 60.75  ? 105 ILE H C   1 
ATOM 2928 O O   . ILE C 3 105 ? -74.528  13.978  -28.750 1.00 72.14  ? 105 ILE H O   1 
ATOM 2929 C CB  . ILE C 3 105 ? -72.747  13.246  -25.803 1.00 59.53  ? 105 ILE H CB  1 
ATOM 2930 C CG1 . ILE C 3 105 ? -72.811  13.621  -24.320 1.00 49.02  ? 105 ILE H CG1 1 
ATOM 2931 C CG2 . ILE C 3 105 ? -71.732  14.123  -26.523 1.00 56.37  ? 105 ILE H CG2 1 
ATOM 2932 C CD1 . ILE C 3 105 ? -71.450  13.763  -23.667 1.00 63.24  ? 105 ILE H CD1 1 
ATOM 2933 N N   . ASP C 3 106 ? -73.485  12.012  -28.376 1.00 59.48  ? 106 ASP H N   1 
ATOM 2934 C CA  . ASP C 3 106 ? -73.530  11.604  -29.778 1.00 56.13  ? 106 ASP H CA  1 
ATOM 2935 C C   . ASP C 3 106 ? -73.748  10.102  -29.945 1.00 55.99  ? 106 ASP H C   1 
ATOM 2936 O O   . ASP C 3 106 ? -73.402  9.549   -30.995 1.00 57.72  ? 106 ASP H O   1 
ATOM 2937 C CB  . ASP C 3 106 ? -72.269  12.038  -30.536 1.00 62.51  ? 106 ASP H CB  1 
ATOM 2938 C CG  . ASP C 3 106 ? -72.519  13.229  -31.451 1.00 58.15  ? 106 ASP H CG  1 
ATOM 2939 O OD1 . ASP C 3 106 ? -73.700  13.552  -31.695 1.00 50.98  ? 106 ASP H OD1 1 
ATOM 2940 O OD2 . ASP C 3 106 ? -71.542  13.847  -31.921 1.00 57.66  ? 106 ASP H OD2 1 
ATOM 2941 N N   . ALA C 3 107 ? -74.314  9.430   -28.945 1.00 59.45  ? 107 ALA H N   1 
ATOM 2942 C CA  . ALA C 3 107 ? -74.775  8.055   -29.109 1.00 56.73  ? 107 ALA H CA  1 
ATOM 2943 C C   . ALA C 3 107 ? -76.161  8.099   -29.742 1.00 53.51  ? 107 ALA H C   1 
ATOM 2944 O O   . ALA C 3 107 ? -77.126  8.548   -29.114 1.00 51.32  ? 107 ALA H O   1 
ATOM 2945 C CB  . ALA C 3 107 ? -74.792  7.325   -27.769 1.00 48.31  ? 107 ALA H CB  1 
ATOM 2946 N N   . LEU C 3 108 ? -76.262  7.638   -30.985 1.00 54.54  ? 108 LEU H N   1 
ATOM 2947 C CA  . LEU C 3 108 ? -77.456  7.870   -31.788 1.00 57.73  ? 108 LEU H CA  1 
ATOM 2948 C C   . LEU C 3 108 ? -78.536  6.851   -31.438 1.00 48.57  ? 108 LEU H C   1 
ATOM 2949 O O   . LEU C 3 108 ? -78.340  5.641   -31.595 1.00 37.83  ? 108 LEU H O   1 
ATOM 2950 C CB  . LEU C 3 108 ? -77.095  7.825   -33.270 1.00 50.37  ? 108 LEU H CB  1 
ATOM 2951 C CG  . LEU C 3 108 ? -76.019  8.869   -33.594 1.00 54.11  ? 108 LEU H CG  1 
ATOM 2952 C CD1 . LEU C 3 108 ? -75.664  8.910   -35.077 1.00 60.16  ? 108 LEU H CD1 1 
ATOM 2953 C CD2 . LEU C 3 108 ? -76.443  10.245  -33.091 1.00 47.23  ? 108 LEU H CD2 1 
ATOM 2954 N N   . ASP C 3 109 ? -79.680  7.353   -30.977 1.00 59.95  ? 109 ASP H N   1 
ATOM 2955 C CA  . ASP C 3 109 ? -80.752  6.525   -30.433 1.00 63.57  ? 109 ASP H CA  1 
ATOM 2956 C C   . ASP C 3 109 ? -81.733  6.091   -31.522 1.00 54.67  ? 109 ASP H C   1 
ATOM 2957 O O   . ASP C 3 109 ? -82.003  4.896   -31.675 1.00 56.19  ? 109 ASP H O   1 
ATOM 2958 C CB  . ASP C 3 109 ? -81.471  7.297   -29.317 1.00 53.83  ? 109 ASP H CB  1 
ATOM 2959 C CG  . ASP C 3 109 ? -82.448  6.437   -28.527 1.00 73.23  ? 109 ASP H CG  1 
ATOM 2960 O OD1 . ASP C 3 109 ? -83.025  5.481   -29.086 1.00 104.36 ? 109 ASP H OD1 1 
ATOM 2961 O OD2 . ASP C 3 109 ? -82.656  6.738   -27.333 1.00 75.55  ? 109 ASP H OD2 1 
ATOM 2962 N N   . VAL C 3 110 ? -82.284  7.047   -32.271 1.00 49.51  ? 110 VAL H N   1 
ATOM 2963 C CA  . VAL C 3 110 ? -83.277  6.766   -33.303 1.00 68.21  ? 110 VAL H CA  1 
ATOM 2964 C C   . VAL C 3 110 ? -82.642  6.993   -34.670 1.00 67.68  ? 110 VAL H C   1 
ATOM 2965 O O   . VAL C 3 110 ? -81.851  7.926   -34.856 1.00 60.41  ? 110 VAL H O   1 
ATOM 2966 C CB  . VAL C 3 110 ? -84.550  7.621   -33.130 1.00 77.84  ? 110 VAL H CB  1 
ATOM 2967 C CG1 . VAL C 3 110 ? -85.078  7.507   -31.702 1.00 62.33  ? 110 VAL H CG1 1 
ATOM 2968 C CG2 . VAL C 3 110 ? -84.314  9.071   -33.520 1.00 67.94  ? 110 VAL H CG2 1 
ATOM 2969 N N   . TRP C 3 111 ? -82.985  6.131   -35.625 1.00 60.69  ? 111 TRP H N   1 
ATOM 2970 C CA  . TRP C 3 111 ? -82.367  6.133   -36.941 1.00 56.14  ? 111 TRP H CA  1 
ATOM 2971 C C   . TRP C 3 111 ? -83.435  6.137   -38.024 1.00 62.37  ? 111 TRP H C   1 
ATOM 2972 O O   . TRP C 3 111 ? -84.561  5.677   -37.814 1.00 53.71  ? 111 TRP H O   1 
ATOM 2973 C CB  . TRP C 3 111 ? -81.451  4.915   -37.128 1.00 50.51  ? 111 TRP H CB  1 
ATOM 2974 C CG  . TRP C 3 111 ? -80.178  4.985   -36.344 1.00 46.69  ? 111 TRP H CG  1 
ATOM 2975 C CD1 . TRP C 3 111 ? -80.036  4.824   -34.998 1.00 46.08  ? 111 TRP H CD1 1 
ATOM 2976 C CD2 . TRP C 3 111 ? -78.861  5.211   -36.863 1.00 49.94  ? 111 TRP H CD2 1 
ATOM 2977 N NE1 . TRP C 3 111 ? -78.714  4.950   -34.643 1.00 57.30  ? 111 TRP H NE1 1 
ATOM 2978 C CE2 . TRP C 3 111 ? -77.972  5.186   -35.770 1.00 47.73  ? 111 TRP H CE2 1 
ATOM 2979 C CE3 . TRP C 3 111 ? -78.348  5.433   -38.146 1.00 44.47  ? 111 TRP H CE3 1 
ATOM 2980 C CZ2 . TRP C 3 111 ? -76.600  5.377   -35.919 1.00 47.74  ? 111 TRP H CZ2 1 
ATOM 2981 C CZ3 . TRP C 3 111 ? -76.986  5.624   -38.292 1.00 48.38  ? 111 TRP H CZ3 1 
ATOM 2982 C CH2 . TRP C 3 111 ? -76.128  5.596   -37.185 1.00 57.65  ? 111 TRP H CH2 1 
ATOM 2983 N N   . GLY C 3 112 ? -83.074  6.681   -39.187 1.00 65.88  ? 112 GLY H N   1 
ATOM 2984 C CA  . GLY C 3 112 ? -83.920  6.568   -40.353 1.00 77.50  ? 112 GLY H CA  1 
ATOM 2985 C C   . GLY C 3 112 ? -83.780  5.212   -41.019 1.00 83.38  ? 112 GLY H C   1 
ATOM 2986 O O   . GLY C 3 112 ? -82.881  4.428   -40.715 1.00 83.88  ? 112 GLY H O   1 
ATOM 2987 N N   . GLN C 3 113 ? -84.693  4.938   -41.952 1.00 80.68  ? 113 GLN H N   1 
ATOM 2988 C CA  . GLN C 3 113 ? -84.675  3.656   -42.647 1.00 73.76  ? 113 GLN H CA  1 
ATOM 2989 C C   . GLN C 3 113 ? -83.450  3.488   -43.537 1.00 77.14  ? 113 GLN H C   1 
ATOM 2990 O O   . GLN C 3 113 ? -83.097  2.352   -43.871 1.00 67.79  ? 113 GLN H O   1 
ATOM 2991 C CB  . GLN C 3 113 ? -85.950  3.487   -43.475 1.00 73.88  ? 113 GLN H CB  1 
ATOM 2992 C CG  . GLN C 3 113 ? -86.017  4.370   -44.713 1.00 83.18  ? 113 GLN H CG  1 
ATOM 2993 C CD  . GLN C 3 113 ? -87.388  4.988   -44.908 1.00 84.77  ? 113 GLN H CD  1 
ATOM 2994 O OE1 . GLN C 3 113 ? -88.058  5.361   -43.943 1.00 78.06  ? 113 GLN H OE1 1 
ATOM 2995 N NE2 . GLN C 3 113 ? -87.816  5.097   -46.161 1.00 99.77  ? 113 GLN H NE2 1 
ATOM 2996 N N   . GLY C 3 114 ? -82.792  4.576   -43.908 1.00 87.40  ? 114 GLY H N   1 
ATOM 2997 C CA  . GLY C 3 114 ? -81.655  4.541   -44.806 1.00 80.63  ? 114 GLY H CA  1 
ATOM 2998 C C   . GLY C 3 114 ? -82.055  4.835   -46.241 1.00 71.50  ? 114 GLY H C   1 
ATOM 2999 O O   . GLY C 3 114 ? -83.198  4.614   -46.657 1.00 76.41  ? 114 GLY H O   1 
ATOM 3000 N N   . THR C 3 115 ? -81.098  5.349   -47.014 1.00 77.36  ? 115 THR H N   1 
ATOM 3001 C CA  . THR C 3 115 ? -81.316  5.658   -48.425 1.00 77.91  ? 115 THR H CA  1 
ATOM 3002 C C   . THR C 3 115 ? -80.093  5.220   -49.216 1.00 87.48  ? 115 THR H C   1 
ATOM 3003 O O   . THR C 3 115 ? -78.975  5.643   -48.910 1.00 76.52  ? 115 THR H O   1 
ATOM 3004 C CB  . THR C 3 115 ? -81.581  7.155   -48.636 1.00 80.02  ? 115 THR H CB  1 
ATOM 3005 O OG1 . THR C 3 115 ? -82.932  7.463   -48.271 1.00 74.18  ? 115 THR H OG1 1 
ATOM 3006 C CG2 . THR C 3 115 ? -81.354  7.543   -50.092 1.00 96.99  ? 115 THR H CG2 1 
ATOM 3007 N N   . ARG C 3 116 ? -80.301  4.381   -50.228 1.00 84.01  ? 116 ARG H N   1 
ATOM 3008 C CA  . ARG C 3 116 ? -79.207  3.886   -51.054 1.00 81.17  ? 116 ARG H CA  1 
ATOM 3009 C C   . ARG C 3 116 ? -78.935  4.863   -52.192 1.00 90.96  ? 116 ARG H C   1 
ATOM 3010 O O   . ARG C 3 116 ? -79.863  5.287   -52.888 1.00 76.90  ? 116 ARG H O   1 
ATOM 3011 C CB  . ARG C 3 116 ? -79.532  2.499   -51.610 1.00 93.94  ? 116 ARG H CB  1 
ATOM 3012 C CG  . ARG C 3 116 ? -78.412  1.884   -52.443 1.00 101.87 ? 116 ARG H CG  1 
ATOM 3013 C CD  . ARG C 3 116 ? -78.756  0.468   -52.883 1.00 106.62 ? 116 ARG H CD  1 
ATOM 3014 N NE  . ARG C 3 116 ? -79.301  -0.324  -51.786 1.00 127.16 ? 116 ARG H NE  1 
ATOM 3015 C CZ  . ARG C 3 116 ? -78.571  -0.913  -50.849 1.00 117.97 ? 116 ARG H CZ  1 
ATOM 3016 N NH1 . ARG C 3 116 ? -77.250  -0.825  -50.844 1.00 109.75 ? 116 ARG H NH1 1 
ATOM 3017 N NH2 . ARG C 3 116 ? -79.180  -1.606  -49.891 1.00 119.42 ? 116 ARG H NH2 1 
ATOM 3018 N N   . VAL C 3 117 ? -77.666  5.222   -52.373 1.00 83.40  ? 117 VAL H N   1 
ATOM 3019 C CA  . VAL C 3 117 ? -77.237  6.142   -53.419 1.00 77.30  ? 117 VAL H CA  1 
ATOM 3020 C C   . VAL C 3 117 ? -76.188  5.435   -54.263 1.00 91.88  ? 117 VAL H C   1 
ATOM 3021 O O   . VAL C 3 117 ? -75.136  5.029   -53.749 1.00 64.12  ? 117 VAL H O   1 
ATOM 3022 C CB  . VAL C 3 117 ? -76.687  7.454   -52.840 1.00 80.41  ? 117 VAL H CB  1 
ATOM 3023 C CG1 . VAL C 3 117 ? -75.828  8.174   -53.866 1.00 75.30  ? 117 VAL H CG1 1 
ATOM 3024 C CG2 . VAL C 3 117 ? -77.831  8.347   -52.388 1.00 92.99  ? 117 VAL H CG2 1 
ATOM 3025 N N   . THR C 3 118 ? -76.473  5.303   -55.558 1.00 112.25 ? 118 THR H N   1 
ATOM 3026 C CA  . THR C 3 118 ? -75.612  4.602   -56.503 1.00 103.17 ? 118 THR H CA  1 
ATOM 3027 C C   . THR C 3 118 ? -74.957  5.628   -57.418 1.00 100.12 ? 118 THR H C   1 
ATOM 3028 O O   . THR C 3 118 ? -75.623  6.218   -58.276 1.00 107.35 ? 118 THR H O   1 
ATOM 3029 C CB  . THR C 3 118 ? -76.408  3.584   -57.319 1.00 95.33  ? 118 THR H CB  1 
ATOM 3030 O OG1 . THR C 3 118 ? -77.379  2.945   -56.481 1.00 104.62 ? 118 THR H OG1 1 
ATOM 3031 C CG2 . THR C 3 118 ? -75.480  2.528   -57.902 1.00 79.74  ? 118 THR H CG2 1 
ATOM 3032 N N   . VAL C 3 119 ? -73.655  5.836   -57.239 1.00 95.51  ? 119 VAL H N   1 
ATOM 3033 C CA  . VAL C 3 119 ? -72.869  6.632   -58.175 1.00 107.50 ? 119 VAL H CA  1 
ATOM 3034 C C   . VAL C 3 119 ? -72.651  5.777   -59.420 1.00 104.56 ? 119 VAL H C   1 
ATOM 3035 O O   . VAL C 3 119 ? -71.882  4.812   -59.401 1.00 96.03  ? 119 VAL H O   1 
ATOM 3036 C CB  . VAL C 3 119 ? -71.540  7.085   -57.557 1.00 90.25  ? 119 VAL H CB  1 
ATOM 3037 C CG1 . VAL C 3 119 ? -70.570  7.544   -58.638 1.00 91.93  ? 119 VAL H CG1 1 
ATOM 3038 C CG2 . VAL C 3 119 ? -71.788  8.200   -56.555 1.00 84.76  ? 119 VAL H CG2 1 
ATOM 3039 N N   . SER C 3 120 ? -73.342  6.123   -60.503 1.00 97.69  ? 120 SER H N   1 
ATOM 3040 C CA  . SER C 3 120 ? -73.431  5.267   -61.673 1.00 117.97 ? 120 SER H CA  1 
ATOM 3041 C C   . SER C 3 120 ? -72.282  5.537   -62.643 1.00 116.07 ? 120 SER H C   1 
ATOM 3042 O O   . SER C 3 120 ? -71.359  6.305   -62.369 1.00 118.16 ? 120 SER H O   1 
ATOM 3043 C CB  . SER C 3 120 ? -74.780  5.462   -62.366 1.00 117.42 ? 120 SER H CB  1 
ATOM 3044 O OG  . SER C 3 120 ? -74.772  6.602   -63.210 1.00 91.20  ? 120 SER H OG  1 
ATOM 3045 N N   . SER C 3 121 ? -72.325  4.847   -63.783 1.00 113.91 ? 121 SER H N   1 
ATOM 3046 C CA  . SER C 3 121 ? -71.499  5.180   -64.936 1.00 125.74 ? 121 SER H CA  1 
ATOM 3047 C C   . SER C 3 121 ? -72.293  5.016   -66.226 1.00 118.54 ? 121 SER H C   1 
ATOM 3048 O O   . SER C 3 121 ? -71.710  5.103   -67.314 1.00 101.53 ? 121 SER H O   1 
ATOM 3049 C CB  . SER C 3 121 ? -70.232  4.314   -64.977 1.00 131.55 ? 121 SER H CB  1 
ATOM 3050 O OG  . SER C 3 121 ? -69.263  4.778   -64.051 1.00 109.05 ? 121 SER H OG  1 
ATOM 3051 N N   . ALA C 3 122 ? -73.597  4.778   -66.128 1.00 115.32 ? 122 ALA H N   1 
ATOM 3052 C CA  . ALA C 3 122 ? -74.473  4.456   -67.245 1.00 116.60 ? 122 ALA H CA  1 
ATOM 3053 C C   . ALA C 3 122 ? -75.905  4.774   -66.812 1.00 113.99 ? 122 ALA H C   1 
ATOM 3054 O O   . ALA C 3 122 ? -76.120  5.490   -65.829 1.00 112.63 ? 122 ALA H O   1 
ATOM 3055 C CB  . ALA C 3 122 ? -74.282  2.991   -67.673 1.00 112.56 ? 122 ALA H CB  1 
ATOM 3056 N N   . SER C 3 123 ? -76.881  4.248   -67.550 1.00 126.94 ? 123 SER H N   1 
ATOM 3057 C CA  . SER C 3 123 ? -78.286  4.377   -67.177 1.00 108.66 ? 123 SER H CA  1 
ATOM 3058 C C   . SER C 3 123 ? -78.966  3.018   -67.286 1.00 103.82 ? 123 SER H C   1 
ATOM 3059 O O   . SER C 3 123 ? -78.284  1.994   -67.396 1.00 109.32 ? 123 SER H O   1 
ATOM 3060 C CB  . SER C 3 123 ? -78.995  5.413   -68.053 1.00 126.84 ? 123 SER H CB  1 
ATOM 3061 O OG  . SER C 3 123 ? -78.570  6.729   -67.739 1.00 116.10 ? 123 SER H OG  1 
ATOM 3062 N N   . THR C 3 124 ? -80.299  2.998   -67.234 1.00 87.82  ? 124 THR H N   1 
ATOM 3063 C CA  . THR C 3 124 ? -81.059  1.754   -67.323 1.00 99.28  ? 124 THR H CA  1 
ATOM 3064 C C   . THR C 3 124 ? -80.601  0.920   -68.513 1.00 121.27 ? 124 THR H C   1 
ATOM 3065 O O   . THR C 3 124 ? -80.732  1.341   -69.667 1.00 137.75 ? 124 THR H O   1 
ATOM 3066 C CB  . THR C 3 124 ? -82.553  2.064   -67.444 1.00 89.86  ? 124 THR H CB  1 
ATOM 3067 O OG1 . THR C 3 124 ? -83.000  2.758   -66.274 1.00 79.92  ? 124 THR H OG1 1 
ATOM 3068 C CG2 . THR C 3 124 ? -83.350  0.778   -67.589 1.00 98.93  ? 124 THR H CG2 1 
ATOM 3069 N N   . LYS C 3 125 ? -80.061  -0.265  -68.229 1.00 126.75 ? 125 LYS H N   1 
ATOM 3070 C CA  . LYS C 3 125 ? -79.469  -1.109  -69.260 1.00 143.27 ? 125 LYS H CA  1 
ATOM 3071 C C   . LYS C 3 125 ? -79.663  -2.569  -68.880 1.00 150.39 ? 125 LYS H C   1 
ATOM 3072 O O   . LYS C 3 125 ? -79.343  -2.963  -67.755 1.00 155.36 ? 125 LYS H O   1 
ATOM 3073 C CB  . LYS C 3 125 ? -77.980  -0.784  -69.434 1.00 138.60 ? 125 LYS H CB  1 
ATOM 3074 C CG  . LYS C 3 125 ? -77.703  0.232   -70.530 1.00 138.34 ? 125 LYS H CG  1 
ATOM 3075 C CD  . LYS C 3 125 ? -76.600  1.200   -70.127 1.00 124.67 ? 125 LYS H CD  1 
ATOM 3076 C CE  . LYS C 3 125 ? -76.528  2.372   -71.093 1.00 129.56 ? 125 LYS H CE  1 
ATOM 3077 N NZ  . LYS C 3 125 ? -75.583  3.429   -70.636 1.00 110.67 ? 125 LYS H NZ  1 
ATOM 3078 N N   . GLY C 3 126 ? -80.171  -3.365  -69.821 1.00 158.36 ? 126 GLY H N   1 
ATOM 3079 C CA  . GLY C 3 126 ? -80.581  -4.724  -69.548 1.00 166.24 ? 126 GLY H CA  1 
ATOM 3080 C C   . GLY C 3 126 ? -79.444  -5.715  -69.386 1.00 169.33 ? 126 GLY H C   1 
ATOM 3081 O O   . GLY C 3 126 ? -78.287  -5.439  -69.719 1.00 162.56 ? 126 GLY H O   1 
ATOM 3082 N N   . PRO C 3 127 ? -79.765  -6.908  -68.860 1.00 169.99 ? 127 PRO H N   1 
ATOM 3083 C CA  . PRO C 3 127 ? -78.737  -7.927  -68.621 1.00 170.84 ? 127 PRO H CA  1 
ATOM 3084 C C   . PRO C 3 127 ? -78.536  -8.862  -69.803 1.00 176.22 ? 127 PRO H C   1 
ATOM 3085 O O   . PRO C 3 127 ? -79.156  -8.690  -70.857 1.00 179.44 ? 127 PRO H O   1 
ATOM 3086 C CB  . PRO C 3 127 ? -79.299  -8.678  -67.413 1.00 155.68 ? 127 PRO H CB  1 
ATOM 3087 C CG  . PRO C 3 127 ? -80.779  -8.687  -67.693 1.00 155.49 ? 127 PRO H CG  1 
ATOM 3088 C CD  . PRO C 3 127 ? -81.092  -7.384  -68.431 1.00 162.36 ? 127 PRO H CD  1 
ATOM 3089 N N   . SER C 3 128 ? -77.667  -9.859  -69.634 1.00 179.89 ? 128 SER H N   1 
ATOM 3090 C CA  . SER C 3 128 ? -77.521  -10.943 -70.595 1.00 180.36 ? 128 SER H CA  1 
ATOM 3091 C C   . SER C 3 128 ? -77.561  -12.270 -69.848 1.00 181.62 ? 128 SER H C   1 
ATOM 3092 O O   . SER C 3 128 ? -77.088  -12.371 -68.713 1.00 178.11 ? 128 SER H O   1 
ATOM 3093 C CB  . SER C 3 128 ? -76.220  -10.819 -71.398 1.00 179.13 ? 128 SER H CB  1 
ATOM 3094 O OG  . SER C 3 128 ? -76.243  -11.666 -72.533 1.00 174.74 ? 128 SER H OG  1 
ATOM 3095 N N   . VAL C 3 129 ? -78.130  -13.289 -70.496 1.00 179.96 ? 129 VAL H N   1 
ATOM 3096 C CA  . VAL C 3 129 ? -78.441  -14.563 -69.854 1.00 167.01 ? 129 VAL H CA  1 
ATOM 3097 C C   . VAL C 3 129 ? -77.791  -15.695 -70.640 1.00 159.00 ? 129 VAL H C   1 
ATOM 3098 O O   . VAL C 3 129 ? -77.844  -15.713 -71.874 1.00 164.71 ? 129 VAL H O   1 
ATOM 3099 C CB  . VAL C 3 129 ? -79.967  -14.777 -69.744 1.00 154.52 ? 129 VAL H CB  1 
ATOM 3100 C CG1 . VAL C 3 129 ? -80.600  -13.593 -69.061 1.00 160.87 ? 129 VAL H CG1 1 
ATOM 3101 C CG2 . VAL C 3 129 ? -80.607  -14.995 -71.111 1.00 151.20 ? 129 VAL H CG2 1 
ATOM 3102 N N   . PHE C 3 130 ? -77.175  -16.644 -69.925 1.00 162.28 ? 130 PHE H N   1 
ATOM 3103 C CA  . PHE C 3 130 ? -76.492  -17.758 -70.588 1.00 164.52 ? 130 PHE H CA  1 
ATOM 3104 C C   . PHE C 3 130 ? -76.558  -19.028 -69.745 1.00 170.96 ? 130 PHE H C   1 
ATOM 3105 O O   . PHE C 3 130 ? -76.268  -18.972 -68.539 1.00 160.12 ? 130 PHE H O   1 
ATOM 3106 C CB  . PHE C 3 130 ? -75.033  -17.401 -70.882 1.00 151.10 ? 130 PHE H CB  1 
ATOM 3107 C CG  . PHE C 3 130 ? -74.877  -16.242 -71.826 1.00 152.52 ? 130 PHE H CG  1 
ATOM 3108 C CD1 . PHE C 3 130 ? -75.336  -16.325 -73.132 1.00 151.68 ? 130 PHE H CD1 1 
ATOM 3109 C CD2 . PHE C 3 130 ? -74.293  -15.061 -71.400 1.00 149.74 ? 130 PHE H CD2 1 
ATOM 3110 C CE1 . PHE C 3 130 ? -75.212  -15.252 -73.994 1.00 147.65 ? 130 PHE H CE1 1 
ATOM 3111 C CE2 . PHE C 3 130 ? -74.157  -13.989 -72.262 1.00 156.94 ? 130 PHE H CE2 1 
ATOM 3112 C CZ  . PHE C 3 130 ? -74.614  -14.086 -73.561 1.00 153.82 ? 130 PHE H CZ  1 
ATOM 3113 N N   . PRO C 3 131 ? -76.923  -20.174 -70.341 1.00 172.92 ? 131 PRO H N   1 
ATOM 3114 C CA  . PRO C 3 131 ? -77.066  -21.409 -69.555 1.00 176.59 ? 131 PRO H CA  1 
ATOM 3115 C C   . PRO C 3 131 ? -75.752  -22.148 -69.342 1.00 185.74 ? 131 PRO H C   1 
ATOM 3116 O O   . PRO C 3 131 ? -74.683  -21.655 -69.713 1.00 185.01 ? 131 PRO H O   1 
ATOM 3117 C CB  . PRO C 3 131 ? -78.037  -22.239 -70.401 1.00 161.13 ? 131 PRO H CB  1 
ATOM 3118 C CG  . PRO C 3 131 ? -77.740  -21.817 -71.804 1.00 136.82 ? 131 PRO H CG  1 
ATOM 3119 C CD  . PRO C 3 131 ? -77.314  -20.366 -71.749 1.00 148.37 ? 131 PRO H CD  1 
ATOM 3120 N N   . LEU C 3 132 ? -75.828  -23.333 -68.740 1.00 184.65 ? 132 LEU H N   1 
ATOM 3121 C CA  . LEU C 3 132 ? -74.675  -24.184 -68.480 1.00 184.47 ? 132 LEU H CA  1 
ATOM 3122 C C   . LEU C 3 132 ? -74.731  -25.430 -69.363 1.00 184.36 ? 132 LEU H C   1 
ATOM 3123 O O   . LEU C 3 132 ? -75.661  -25.627 -70.150 1.00 179.15 ? 132 LEU H O   1 
ATOM 3124 C CB  . LEU C 3 132 ? -74.608  -24.566 -66.999 1.00 179.13 ? 132 LEU H CB  1 
ATOM 3125 C CG  . LEU C 3 132 ? -74.320  -23.451 -65.991 1.00 178.44 ? 132 LEU H CG  1 
ATOM 3126 C CD1 . LEU C 3 132 ? -73.871  -24.038 -64.660 1.00 172.39 ? 132 LEU H CD1 1 
ATOM 3127 C CD2 . LEU C 3 132 ? -73.277  -22.484 -66.532 1.00 168.08 ? 132 LEU H CD2 1 
ATOM 3128 N N   . ALA C 3 133 ? -73.719  -26.276 -69.217 1.00 189.11 ? 133 ALA H N   1 
ATOM 3129 C CA  . ALA C 3 133 ? -73.559  -27.509 -69.970 1.00 195.28 ? 133 ALA H CA  1 
ATOM 3130 C C   . ALA C 3 133 ? -73.165  -28.632 -69.024 1.00 206.09 ? 133 ALA H C   1 
ATOM 3131 O O   . ALA C 3 133 ? -72.702  -28.375 -67.906 1.00 208.07 ? 133 ALA H O   1 
ATOM 3132 C CB  . ALA C 3 133 ? -72.496  -27.351 -71.069 1.00 178.62 ? 133 ALA H CB  1 
ATOM 3133 N N   . PRO C 3 134 ? -73.373  -29.902 -69.429 1.00 210.99 ? 134 PRO H N   1 
ATOM 3134 C CA  . PRO C 3 134 ? -72.929  -31.033 -68.598 1.00 208.55 ? 134 PRO H CA  1 
ATOM 3135 C C   . PRO C 3 134 ? -71.479  -30.903 -68.156 1.00 199.04 ? 134 PRO H C   1 
ATOM 3136 O O   . PRO C 3 134 ? -70.588  -30.770 -69.002 1.00 198.34 ? 134 PRO H O   1 
ATOM 3137 C CB  . PRO C 3 134 ? -73.108  -32.245 -69.523 1.00 205.37 ? 134 PRO H CB  1 
ATOM 3138 C CG  . PRO C 3 134 ? -74.019  -31.798 -70.634 1.00 184.02 ? 134 PRO H CG  1 
ATOM 3139 C CD  . PRO C 3 134 ? -74.282  -30.328 -70.507 1.00 192.55 ? 134 PRO H CD  1 
ATOM 3140 N N   . SER C 3 135 ? -71.218  -30.930 -66.846 1.00 186.32 ? 135 SER H N   1 
ATOM 3141 C CA  . SER C 3 135 ? -69.849  -30.724 -66.356 1.00 178.69 ? 135 SER H CA  1 
ATOM 3142 C C   . SER C 3 135 ? -69.117  -32.044 -66.129 1.00 178.39 ? 135 SER H C   1 
ATOM 3143 O O   . SER C 3 135 ? -68.165  -32.364 -66.845 1.00 172.87 ? 135 SER H O   1 
ATOM 3144 C CB  . SER C 3 135 ? -69.877  -29.888 -65.075 1.00 177.64 ? 135 SER H CB  1 
ATOM 3145 N N   . SER C 3 136 ? -69.548  -32.819 -65.131 1.00 186.20 ? 136 SER H N   1 
ATOM 3146 C CA  . SER C 3 136 ? -69.011  -34.164 -64.952 1.00 180.63 ? 136 SER H CA  1 
ATOM 3147 C C   . SER C 3 136 ? -70.108  -35.217 -64.855 1.00 174.05 ? 136 SER H C   1 
ATOM 3148 O O   . SER C 3 136 ? -70.112  -36.193 -65.614 1.00 175.08 ? 136 SER H O   1 
ATOM 3149 C CB  . SER C 3 136 ? -68.122  -34.220 -63.707 1.00 172.16 ? 136 SER H CB  1 
ATOM 3150 N N   . LYS C 3 137 ? -71.058  -34.998 -63.947 1.00 168.02 ? 137 LYS H N   1 
ATOM 3151 C CA  . LYS C 3 137 ? -72.063  -35.994 -63.579 1.00 160.94 ? 137 LYS H CA  1 
ATOM 3152 C C   . LYS C 3 137 ? -73.000  -35.439 -62.510 1.00 153.72 ? 137 LYS H C   1 
ATOM 3153 O O   . LYS C 3 137 ? -72.819  -35.696 -61.318 1.00 133.60 ? 137 LYS H O   1 
ATOM 3154 C CB  . LYS C 3 137 ? -71.399  -37.275 -63.079 1.00 159.41 ? 137 LYS H CB  1 
ATOM 3155 N N   . GLY C 3 142 ? -73.662  -38.098 -56.259 1.00 129.31 ? 142 GLY H N   1 
ATOM 3156 C CA  . GLY C 3 142 ? -74.988  -38.123 -55.669 1.00 134.84 ? 142 GLY H CA  1 
ATOM 3157 C C   . GLY C 3 142 ? -75.996  -37.278 -56.422 1.00 154.20 ? 142 GLY H C   1 
ATOM 3158 O O   . GLY C 3 142 ? -76.650  -37.755 -57.351 1.00 147.33 ? 142 GLY H O   1 
ATOM 3159 N N   . THR C 3 143 ? -76.123  -36.016 -56.020 1.00 165.86 ? 143 THR H N   1 
ATOM 3160 C CA  . THR C 3 143 ? -77.045  -35.087 -56.654 1.00 160.91 ? 143 THR H CA  1 
ATOM 3161 C C   . THR C 3 143 ? -76.331  -34.352 -57.789 1.00 163.85 ? 143 THR H C   1 
ATOM 3162 O O   . THR C 3 143 ? -75.205  -34.689 -58.166 1.00 161.31 ? 143 THR H O   1 
ATOM 3163 C CB  . THR C 3 143 ? -77.617  -34.118 -55.621 1.00 150.58 ? 143 THR H CB  1 
ATOM 3164 O OG1 . THR C 3 143 ? -76.551  -33.373 -55.019 1.00 143.98 ? 143 THR H OG1 1 
ATOM 3165 C CG2 . THR C 3 143 ? -78.372  -34.877 -54.539 1.00 146.47 ? 143 THR H CG2 1 
ATOM 3166 N N   . ALA C 3 144 ? -76.984  -33.336 -58.350 1.00 173.87 ? 144 ALA H N   1 
ATOM 3167 C CA  . ALA C 3 144 ? -76.404  -32.548 -59.427 1.00 166.70 ? 144 ALA H CA  1 
ATOM 3168 C C   . ALA C 3 144 ? -76.936  -31.126 -59.340 1.00 174.22 ? 144 ALA H C   1 
ATOM 3169 O O   . ALA C 3 144 ? -78.124  -30.914 -59.075 1.00 176.50 ? 144 ALA H O   1 
ATOM 3170 C CB  . ALA C 3 144 ? -76.721  -33.152 -60.799 1.00 139.06 ? 144 ALA H CB  1 
ATOM 3171 N N   . ALA C 3 145 ? -76.051  -30.159 -59.573 1.00 169.71 ? 145 ALA H N   1 
ATOM 3172 C CA  . ALA C 3 145 ? -76.381  -28.743 -59.491 1.00 162.16 ? 145 ALA H CA  1 
ATOM 3173 C C   . ALA C 3 145 ? -76.123  -28.084 -60.837 1.00 167.78 ? 145 ALA H C   1 
ATOM 3174 O O   . ALA C 3 145 ? -75.079  -28.315 -61.456 1.00 162.52 ? 145 ALA H O   1 
ATOM 3175 C CB  . ALA C 3 145 ? -75.565  -28.052 -58.395 1.00 150.44 ? 145 ALA H CB  1 
ATOM 3176 N N   . LEU C 3 146 ? -77.074  -27.268 -61.287 1.00 180.37 ? 146 LEU H N   1 
ATOM 3177 C CA  . LEU C 3 146 ? -76.945  -26.529 -62.535 1.00 178.40 ? 146 LEU H CA  1 
ATOM 3178 C C   . LEU C 3 146 ? -77.388  -25.089 -62.314 1.00 188.13 ? 146 LEU H C   1 
ATOM 3179 O O   . LEU C 3 146 ? -78.158  -24.788 -61.398 1.00 197.40 ? 146 LEU H O   1 
ATOM 3180 C CB  . LEU C 3 146 ? -77.754  -27.177 -63.671 1.00 171.40 ? 146 LEU H CB  1 
ATOM 3181 C CG  . LEU C 3 146 ? -79.272  -26.992 -63.709 1.00 165.82 ? 146 LEU H CG  1 
ATOM 3182 C CD1 . LEU C 3 146 ? -79.799  -27.323 -65.090 1.00 169.45 ? 146 LEU H CD1 1 
ATOM 3183 C CD2 . LEU C 3 146 ? -79.944  -27.878 -62.678 1.00 171.23 ? 146 LEU H CD2 1 
ATOM 3184 N N   . GLY C 3 147 ? -76.884  -24.189 -63.168 1.00 189.41 ? 147 GLY H N   1 
ATOM 3185 C CA  . GLY C 3 147 ? -77.065  -22.770 -62.955 1.00 189.70 ? 147 GLY H CA  1 
ATOM 3186 C C   . GLY C 3 147 ? -77.413  -22.029 -64.231 1.00 182.58 ? 147 GLY H C   1 
ATOM 3187 O O   . GLY C 3 147 ? -77.436  -22.597 -65.324 1.00 186.02 ? 147 GLY H O   1 
ATOM 3188 N N   . CYS C 3 148 ? -77.688  -20.733 -64.058 1.00 172.68 ? 148 CYS H N   1 
ATOM 3189 C CA  . CYS C 3 148 ? -78.064  -19.837 -65.153 1.00 186.16 ? 148 CYS H CA  1 
ATOM 3190 C C   . CYS C 3 148 ? -77.326  -18.518 -64.933 1.00 182.70 ? 148 CYS H C   1 
ATOM 3191 O O   . CYS C 3 148 ? -77.708  -17.725 -64.067 1.00 172.92 ? 148 CYS H O   1 
ATOM 3192 C CB  . CYS C 3 148 ? -79.575  -19.631 -65.203 1.00 191.44 ? 148 CYS H CB  1 
ATOM 3193 S SG  . CYS C 3 148 ? -80.548  -21.159 -65.097 1.00 213.00 ? 148 CYS H SG  1 
ATOM 3194 N N   . LEU C 3 149 ? -76.278  -18.285 -65.721 1.00 187.27 ? 149 LEU H N   1 
ATOM 3195 C CA  . LEU C 3 149 ? -75.414  -17.127 -65.525 1.00 179.45 ? 149 LEU H CA  1 
ATOM 3196 C C   . LEU C 3 149 ? -76.051  -15.862 -66.091 1.00 178.62 ? 149 LEU H C   1 
ATOM 3197 O O   . LEU C 3 149 ? -76.675  -15.884 -67.156 1.00 187.18 ? 149 LEU H O   1 
ATOM 3198 C CB  . LEU C 3 149 ? -74.054  -17.368 -66.181 1.00 179.35 ? 149 LEU H CB  1 
ATOM 3199 C CG  . LEU C 3 149 ? -72.873  -16.525 -65.692 1.00 166.13 ? 149 LEU H CG  1 
ATOM 3200 C CD1 . LEU C 3 149 ? -72.682  -16.682 -64.191 1.00 149.09 ? 149 LEU H CD1 1 
ATOM 3201 C CD2 . LEU C 3 149 ? -71.603  -16.901 -66.439 1.00 145.20 ? 149 LEU H CD2 1 
ATOM 3202 N N   . VAL C 3 150 ? -75.882  -14.751 -65.368 1.00 179.69 ? 150 VAL H N   1 
ATOM 3203 C CA  . VAL C 3 150 ? -76.425  -13.451 -65.747 1.00 178.85 ? 150 VAL H CA  1 
ATOM 3204 C C   . VAL C 3 150 ? -75.307  -12.418 -65.708 1.00 174.11 ? 150 VAL H C   1 
ATOM 3205 O O   . VAL C 3 150 ? -74.343  -12.547 -64.946 1.00 169.82 ? 150 VAL H O   1 
ATOM 3206 C CB  . VAL C 3 150 ? -77.588  -13.019 -64.824 1.00 162.06 ? 150 VAL H CB  1 
ATOM 3207 C CG1 . VAL C 3 150 ? -78.424  -11.926 -65.478 1.00 170.55 ? 150 VAL H CG1 1 
ATOM 3208 C CG2 . VAL C 3 150 ? -78.451  -14.216 -64.445 1.00 157.28 ? 150 VAL H CG2 1 
ATOM 3209 N N   . LYS C 3 151 ? -75.446  -11.377 -66.531 1.00 175.76 ? 151 LYS H N   1 
ATOM 3210 C CA  . LYS C 3 151 ? -74.402  -10.368 -66.657 1.00 167.76 ? 151 LYS H CA  1 
ATOM 3211 C C   . LYS C 3 151 ? -75.006  -8.995  -66.919 1.00 168.01 ? 151 LYS H C   1 
ATOM 3212 O O   . LYS C 3 151 ? -76.163  -8.865  -67.330 1.00 170.70 ? 151 LYS H O   1 
ATOM 3213 C CB  . LYS C 3 151 ? -73.420  -10.706 -67.784 1.00 144.22 ? 151 LYS H CB  1 
ATOM 3214 C CG  . LYS C 3 151 ? -72.482  -11.850 -67.481 1.00 144.07 ? 151 LYS H CG  1 
ATOM 3215 C CD  . LYS C 3 151 ? -71.288  -11.828 -68.410 1.00 128.58 ? 151 LYS H CD  1 
ATOM 3216 C CE  . LYS C 3 151 ? -70.371  -12.992 -68.118 1.00 129.61 ? 151 LYS H CE  1 
ATOM 3217 N NZ  . LYS C 3 151 ? -71.012  -14.289 -68.466 1.00 120.86 ? 151 LYS H NZ  1 
ATOM 3218 N N   . ASP C 3 152 ? -74.177  -7.971  -66.695 1.00 170.58 ? 152 ASP H N   1 
ATOM 3219 C CA  . ASP C 3 152 ? -74.437  -6.584  -67.090 1.00 158.82 ? 152 ASP H CA  1 
ATOM 3220 C C   . ASP C 3 152 ? -75.681  -6.019  -66.396 1.00 158.10 ? 152 ASP H C   1 
ATOM 3221 O O   . ASP C 3 152 ? -76.697  -5.695  -67.015 1.00 156.97 ? 152 ASP H O   1 
ATOM 3222 C CB  . ASP C 3 152 ? -74.545  -6.478  -68.615 1.00 143.43 ? 152 ASP H CB  1 
ATOM 3223 C CG  . ASP C 3 152 ? -73.384  -7.150  -69.323 1.00 150.91 ? 152 ASP H CG  1 
ATOM 3224 O OD1 . ASP C 3 152 ? -72.221  -6.842  -68.986 1.00 137.41 ? 152 ASP H OD1 1 
ATOM 3225 O OD2 . ASP C 3 152 ? -73.633  -7.990  -70.212 1.00 171.48 ? 152 ASP H OD2 1 
ATOM 3226 N N   . TYR C 3 153 ? -75.560  -5.905  -65.075 1.00 155.21 ? 153 TYR H N   1 
ATOM 3227 C CA  . TYR C 3 153 ? -76.560  -5.231  -64.260 1.00 147.46 ? 153 TYR H CA  1 
ATOM 3228 C C   . TYR C 3 153 ? -76.511  -3.722  -64.494 1.00 140.97 ? 153 TYR H C   1 
ATOM 3229 O O   . TYR C 3 153 ? -75.686  -3.207  -65.252 1.00 119.25 ? 153 TYR H O   1 
ATOM 3230 C CB  . TYR C 3 153 ? -76.317  -5.509  -62.780 1.00 140.42 ? 153 TYR H CB  1 
ATOM 3231 C CG  . TYR C 3 153 ? -77.137  -6.617  -62.175 1.00 145.80 ? 153 TYR H CG  1 
ATOM 3232 C CD1 . TYR C 3 153 ? -76.889  -7.943  -62.496 1.00 147.41 ? 153 TYR H CD1 1 
ATOM 3233 C CD2 . TYR C 3 153 ? -78.147  -6.338  -61.264 1.00 149.15 ? 153 TYR H CD2 1 
ATOM 3234 C CE1 . TYR C 3 153 ? -77.635  -8.958  -61.941 1.00 150.43 ? 153 TYR H CE1 1 
ATOM 3235 C CE2 . TYR C 3 153 ? -78.899  -7.349  -60.702 1.00 160.18 ? 153 TYR H CE2 1 
ATOM 3236 C CZ  . TYR C 3 153 ? -78.638  -8.658  -61.043 1.00 161.47 ? 153 TYR H CZ  1 
ATOM 3237 O OH  . TYR C 3 153 ? -79.383  -9.672  -60.486 1.00 165.86 ? 153 TYR H OH  1 
ATOM 3238 N N   . PHE C 3 154 ? -77.430  -3.008  -63.824 1.00 152.56 ? 154 PHE H N   1 
ATOM 3239 C CA  . PHE C 3 154 ? -77.254  -1.598  -63.483 1.00 152.80 ? 154 PHE H CA  1 
ATOM 3240 C C   . PHE C 3 154 ? -78.363  -1.065  -62.574 1.00 158.28 ? 154 PHE H C   1 
ATOM 3241 O O   . PHE C 3 154 ? -78.064  -0.617  -61.460 1.00 166.85 ? 154 PHE H O   1 
ATOM 3242 C CB  . PHE C 3 154 ? -77.138  -0.710  -64.724 1.00 130.20 ? 154 PHE H CB  1 
ATOM 3243 C CG  . PHE C 3 154 ? -76.189  0.425   -64.540 1.00 133.01 ? 154 PHE H CG  1 
ATOM 3244 C CD1 . PHE C 3 154 ? -74.831  0.187   -64.415 1.00 133.30 ? 154 PHE H CD1 1 
ATOM 3245 C CD2 . PHE C 3 154 ? -76.651  1.723   -64.441 1.00 137.64 ? 154 PHE H CD2 1 
ATOM 3246 C CE1 . PHE C 3 154 ? -73.949  1.225   -64.227 1.00 140.25 ? 154 PHE H CE1 1 
ATOM 3247 C CE2 . PHE C 3 154 ? -75.775  2.763   -64.252 1.00 140.76 ? 154 PHE H CE2 1 
ATOM 3248 C CZ  . PHE C 3 154 ? -74.422  2.514   -64.144 1.00 142.89 ? 154 PHE H CZ  1 
ATOM 3249 N N   . PRO C 3 155 ? -79.649  -1.080  -62.985 1.00 150.56 ? 155 PRO H N   1 
ATOM 3250 C CA  . PRO C 3 155 ? -80.669  -0.405  -62.170 1.00 148.15 ? 155 PRO H CA  1 
ATOM 3251 C C   . PRO C 3 155 ? -81.014  -1.144  -60.884 1.00 167.48 ? 155 PRO H C   1 
ATOM 3252 O O   . PRO C 3 155 ? -82.165  -1.558  -60.708 1.00 174.72 ? 155 PRO H O   1 
ATOM 3253 C CB  . PRO C 3 155 ? -81.885  -0.339  -63.108 1.00 135.29 ? 155 PRO H CB  1 
ATOM 3254 C CG  . PRO C 3 155 ? -81.364  -0.698  -64.470 1.00 131.98 ? 155 PRO H CG  1 
ATOM 3255 C CD  . PRO C 3 155 ? -80.252  -1.648  -64.200 1.00 135.88 ? 155 PRO H CD  1 
ATOM 3256 N N   . GLU C 3 156 ? -80.024  -1.325  -59.990 1.00 169.93 ? 156 GLU H N   1 
ATOM 3257 C CA  . GLU C 3 156 ? -80.209  -1.837  -58.632 1.00 162.30 ? 156 GLU H CA  1 
ATOM 3258 C C   . GLU C 3 156 ? -80.578  -3.320  -58.658 1.00 170.16 ? 156 GLU H C   1 
ATOM 3259 O O   . GLU C 3 156 ? -81.131  -3.800  -59.656 1.00 172.12 ? 156 GLU H O   1 
ATOM 3260 C CB  . GLU C 3 156 ? -81.260  -0.977  -57.910 1.00 158.61 ? 156 GLU H CB  1 
ATOM 3261 C CG  . GLU C 3 156 ? -81.739  -1.442  -56.544 1.00 163.20 ? 156 GLU H CG  1 
ATOM 3262 C CD  . GLU C 3 156 ? -83.072  -2.157  -56.601 1.00 158.21 ? 156 GLU H CD  1 
ATOM 3263 O OE1 . GLU C 3 156 ? -83.721  -2.131  -57.668 1.00 150.68 ? 156 GLU H OE1 1 
ATOM 3264 O OE2 . GLU C 3 156 ? -83.480  -2.740  -55.574 1.00 166.10 ? 156 GLU H OE2 1 
ATOM 3265 N N   . PRO C 3 157 ? -80.241  -4.090  -57.622 1.00 176.35 ? 157 PRO H N   1 
ATOM 3266 C CA  . PRO C 3 157 ? -80.640  -5.504  -57.593 1.00 177.75 ? 157 PRO H CA  1 
ATOM 3267 C C   . PRO C 3 157 ? -82.143  -5.669  -57.775 1.00 178.98 ? 157 PRO H C   1 
ATOM 3268 O O   . PRO C 3 157 ? -82.945  -4.985  -57.137 1.00 173.24 ? 157 PRO H O   1 
ATOM 3269 C CB  . PRO C 3 157 ? -80.183  -5.962  -56.206 1.00 160.62 ? 157 PRO H CB  1 
ATOM 3270 C CG  . PRO C 3 157 ? -78.970  -5.137  -55.945 1.00 145.83 ? 157 PRO H CG  1 
ATOM 3271 C CD  . PRO C 3 157 ? -79.220  -3.793  -56.598 1.00 168.61 ? 157 PRO H CD  1 
ATOM 3272 N N   . VAL C 3 158 ? -82.527  -6.608  -58.638 1.00 174.87 ? 158 VAL H N   1 
ATOM 3273 C CA  . VAL C 3 158 ? -83.887  -6.676  -59.152 1.00 173.90 ? 158 VAL H CA  1 
ATOM 3274 C C   . VAL C 3 158 ? -84.507  -8.038  -58.865 1.00 172.30 ? 158 VAL H C   1 
ATOM 3275 O O   . VAL C 3 158 ? -83.818  -9.036  -58.639 1.00 172.06 ? 158 VAL H O   1 
ATOM 3276 C CB  . VAL C 3 158 ? -83.931  -6.370  -60.661 1.00 169.72 ? 158 VAL H CB  1 
ATOM 3277 C CG1 . VAL C 3 158 ? -83.836  -4.882  -60.889 1.00 175.94 ? 158 VAL H CG1 1 
ATOM 3278 C CG2 . VAL C 3 158 ? -82.771  -7.057  -61.349 1.00 164.31 ? 158 VAL H CG2 1 
ATOM 3279 N N   . THR C 3 159 ? -85.840  -8.058  -58.883 1.00 169.19 ? 159 THR H N   1 
ATOM 3280 C CA  . THR C 3 159 ? -86.631  -9.257  -58.648 1.00 165.81 ? 159 THR H CA  1 
ATOM 3281 C C   . THR C 3 159 ? -87.756  -9.326  -59.672 1.00 171.58 ? 159 THR H C   1 
ATOM 3282 O O   . THR C 3 159 ? -88.354  -8.303  -60.017 1.00 168.45 ? 159 THR H O   1 
ATOM 3283 C CB  . THR C 3 159 ? -87.209  -9.276  -57.223 1.00 143.68 ? 159 THR H CB  1 
ATOM 3284 O OG1 . THR C 3 159 ? -88.166  -10.336 -57.101 1.00 140.83 ? 159 THR H OG1 1 
ATOM 3285 C CG2 . THR C 3 159 ? -87.875  -7.945  -56.891 1.00 131.29 ? 159 THR H CG2 1 
ATOM 3286 N N   . VAL C 3 160 ? -88.033  -10.536 -60.160 1.00 178.06 ? 160 VAL H N   1 
ATOM 3287 C CA  . VAL C 3 160 ? -89.104  -10.757 -61.127 1.00 173.13 ? 160 VAL H CA  1 
ATOM 3288 C C   . VAL C 3 160 ? -89.514  -12.225 -61.086 1.00 175.05 ? 160 VAL H C   1 
ATOM 3289 O O   . VAL C 3 160 ? -88.661  -13.119 -61.080 1.00 180.33 ? 160 VAL H O   1 
ATOM 3290 C CB  . VAL C 3 160 ? -88.675  -10.330 -62.544 1.00 168.91 ? 160 VAL H CB  1 
ATOM 3291 C CG1 . VAL C 3 160 ? -87.294  -10.883 -62.882 1.00 165.10 ? 160 VAL H CG1 1 
ATOM 3292 C CG2 . VAL C 3 160 ? -89.706  -10.765 -63.570 1.00 164.68 ? 160 VAL H CG2 1 
ATOM 3293 N N   . SER C 3 161 ? -90.821  -12.485 -61.053 1.00 169.16 ? 161 SER H N   1 
ATOM 3294 C CA  . SER C 3 161 ? -91.344  -13.839 -60.916 1.00 175.26 ? 161 SER H CA  1 
ATOM 3295 C C   . SER C 3 161 ? -92.367  -14.124 -62.006 1.00 187.08 ? 161 SER H C   1 
ATOM 3296 O O   . SER C 3 161 ? -93.335  -13.375 -62.167 1.00 201.00 ? 161 SER H O   1 
ATOM 3297 C CB  . SER C 3 161 ? -91.978  -14.045 -59.536 1.00 165.97 ? 161 SER H CB  1 
ATOM 3298 O OG  . SER C 3 161 ? -92.563  -15.332 -59.430 1.00 161.80 ? 161 SER H OG  1 
ATOM 3299 N N   . TRP C 3 162 ? -92.146  -15.211 -62.745 1.00 194.27 ? 162 TRP H N   1 
ATOM 3300 C CA  . TRP C 3 162 ? -93.107  -15.722 -63.716 1.00 195.06 ? 162 TRP H CA  1 
ATOM 3301 C C   . TRP C 3 162 ? -92.812  -17.199 -63.932 1.00 202.75 ? 162 TRP H C   1 
ATOM 3302 O O   . TRP C 3 162 ? -91.663  -17.565 -64.190 1.00 206.91 ? 162 TRP H O   1 
ATOM 3303 C CB  . TRP C 3 162 ? -93.040  -14.952 -65.041 1.00 178.22 ? 162 TRP H CB  1 
ATOM 3304 C CG  . TRP C 3 162 ? -94.002  -13.799 -65.115 1.00 167.92 ? 162 TRP H CG  1 
ATOM 3305 C CD1 . TRP C 3 162 ? -95.356  -13.851 -64.945 1.00 166.89 ? 162 TRP H CD1 1 
ATOM 3306 C CD2 . TRP C 3 162 ? -93.685  -12.425 -65.374 1.00 165.18 ? 162 TRP H CD2 1 
ATOM 3307 N NE1 . TRP C 3 162 ? -95.900  -12.597 -65.084 1.00 170.11 ? 162 TRP H NE1 1 
ATOM 3308 C CE2 . TRP C 3 162 ? -94.896  -11.704 -65.347 1.00 166.91 ? 162 TRP H CE2 1 
ATOM 3309 C CE3 . TRP C 3 162 ? -92.496  -11.735 -65.626 1.00 161.91 ? 162 TRP H CE3 1 
ATOM 3310 C CZ2 . TRP C 3 162 ? -94.950  -10.327 -65.563 1.00 150.20 ? 162 TRP H CZ2 1 
ATOM 3311 C CZ3 . TRP C 3 162 ? -92.553  -10.369 -65.840 1.00 158.06 ? 162 TRP H CZ3 1 
ATOM 3312 C CH2 . TRP C 3 162 ? -93.771  -9.680  -65.807 1.00 144.82 ? 162 TRP H CH2 1 
ATOM 3313 N N   . ASN C 3 163 ? -93.847  -18.035 -63.816 1.00 204.11 ? 163 ASN H N   1 
ATOM 3314 C CA  . ASN C 3 163 ? -93.744  -19.498 -63.816 1.00 197.35 ? 163 ASN H CA  1 
ATOM 3315 C C   . ASN C 3 163 ? -92.854  -20.014 -62.682 1.00 189.73 ? 163 ASN H C   1 
ATOM 3316 O O   . ASN C 3 163 ? -92.452  -21.182 -62.678 1.00 180.09 ? 163 ASN H O   1 
ATOM 3317 C CB  . ASN C 3 163 ? -93.286  -20.038 -65.187 1.00 192.98 ? 163 ASN H CB  1 
ATOM 3318 C CG  . ASN C 3 163 ? -91.775  -20.214 -65.301 1.00 192.16 ? 163 ASN H CG  1 
ATOM 3319 O OD1 . ASN C 3 163 ? -91.246  -21.305 -65.084 1.00 188.52 ? 163 ASN H OD1 1 
ATOM 3320 N ND2 . ASN C 3 163 ? -91.081  -19.145 -65.673 1.00 191.26 ? 163 ASN H ND2 1 
ATOM 3321 N N   . SER C 3 164 ? -92.596  -19.176 -61.680 1.00 185.97 ? 164 SER H N   1 
ATOM 3322 C CA  . SER C 3 164 ? -91.766  -19.548 -60.542 1.00 180.88 ? 164 SER H CA  1 
ATOM 3323 C C   . SER C 3 164 ? -92.578  -20.416 -59.581 1.00 175.54 ? 164 SER H C   1 
ATOM 3324 O O   . SER C 3 164 ? -93.684  -20.866 -59.892 1.00 180.69 ? 164 SER H O   1 
ATOM 3325 C CB  . SER C 3 164 ? -91.213  -18.299 -59.861 1.00 185.55 ? 164 SER H CB  1 
ATOM 3326 O OG  . SER C 3 164 ? -90.676  -17.397 -60.812 1.00 180.80 ? 164 SER H OG  1 
ATOM 3327 N N   . GLY C 3 165 ? -92.036  -20.660 -58.390 1.00 161.88 ? 165 GLY H N   1 
ATOM 3328 C CA  . GLY C 3 165 ? -92.659  -21.599 -57.480 1.00 154.93 ? 165 GLY H CA  1 
ATOM 3329 C C   . GLY C 3 165 ? -92.993  -21.081 -56.095 1.00 155.81 ? 165 GLY H C   1 
ATOM 3330 O O   . GLY C 3 165 ? -92.974  -19.874 -55.834 1.00 143.17 ? 165 GLY H O   1 
ATOM 3331 N N   . ALA C 3 166 ? -93.311  -22.017 -55.205 1.00 167.07 ? 166 ALA H N   1 
ATOM 3332 C CA  . ALA C 3 166 ? -93.734  -21.753 -53.837 1.00 163.70 ? 166 ALA H CA  1 
ATOM 3333 C C   . ALA C 3 166 ? -92.517  -21.771 -52.907 1.00 173.34 ? 166 ALA H C   1 
ATOM 3334 O O   . ALA C 3 166 ? -91.373  -21.647 -53.355 1.00 180.78 ? 166 ALA H O   1 
ATOM 3335 C CB  . ALA C 3 166 ? -94.804  -22.767 -53.421 1.00 147.78 ? 166 ALA H CB  1 
ATOM 3336 N N   . LEU C 3 167 ? -92.761  -21.900 -51.602 1.00 175.87 ? 167 LEU H N   1 
ATOM 3337 C CA  . LEU C 3 167 ? -91.725  -21.921 -50.579 1.00 171.34 ? 167 LEU H CA  1 
ATOM 3338 C C   . LEU C 3 167 ? -90.697  -23.019 -50.883 1.00 178.93 ? 167 LEU H C   1 
ATOM 3339 O O   . LEU C 3 167 ? -90.885  -23.864 -51.762 1.00 192.68 ? 167 LEU H O   1 
ATOM 3340 C CB  . LEU C 3 167 ? -92.376  -22.116 -49.203 1.00 159.84 ? 167 LEU H CB  1 
ATOM 3341 C CG  . LEU C 3 167 ? -91.821  -21.671 -47.838 1.00 160.95 ? 167 LEU H CG  1 
ATOM 3342 C CD1 . LEU C 3 167 ? -92.938  -21.778 -46.812 1.00 152.65 ? 167 LEU H CD1 1 
ATOM 3343 C CD2 . LEU C 3 167 ? -90.632  -22.476 -47.342 1.00 153.87 ? 167 LEU H CD2 1 
ATOM 3344 N N   . THR C 3 168 ? -89.591  -22.984 -50.130 1.00 172.63 ? 168 THR H N   1 
ATOM 3345 C CA  . THR C 3 168 ? -88.375  -23.780 -50.316 1.00 165.23 ? 168 THR H CA  1 
ATOM 3346 C C   . THR C 3 168 ? -88.009  -23.946 -51.788 1.00 173.65 ? 168 THR H C   1 
ATOM 3347 O O   . THR C 3 168 ? -87.997  -22.961 -52.535 1.00 174.00 ? 168 THR H O   1 
ATOM 3348 C CB  . THR C 3 168 ? -88.460  -25.153 -49.610 1.00 153.77 ? 168 THR H CB  1 
ATOM 3349 O OG1 . THR C 3 168 ? -87.357  -25.972 -50.021 1.00 156.19 ? 168 THR H OG1 1 
ATOM 3350 C CG2 . THR C 3 168 ? -89.767  -25.904 -49.871 1.00 144.60 ? 168 THR H CG2 1 
ATOM 3351 N N   . SER C 3 169 ? -87.692  -25.174 -52.210 1.00 177.06 ? 169 SER H N   1 
ATOM 3352 C CA  . SER C 3 169 ? -87.089  -25.430 -53.521 1.00 178.09 ? 169 SER H CA  1 
ATOM 3353 C C   . SER C 3 169 ? -85.784  -24.652 -53.675 1.00 174.35 ? 169 SER H C   1 
ATOM 3354 O O   . SER C 3 169 ? -85.455  -24.155 -54.755 1.00 173.17 ? 169 SER H O   1 
ATOM 3355 C CB  . SER C 3 169 ? -88.057  -25.107 -54.664 1.00 162.39 ? 169 SER H CB  1 
ATOM 3356 O OG  . SER C 3 169 ? -87.403  -25.161 -55.920 1.00 129.65 ? 169 SER H OG  1 
ATOM 3357 N N   . GLY C 3 170 ? -85.034  -24.551 -52.580 1.00 158.93 ? 170 GLY H N   1 
ATOM 3358 C CA  . GLY C 3 170 ? -83.797  -23.802 -52.562 1.00 163.39 ? 170 GLY H CA  1 
ATOM 3359 C C   . GLY C 3 170 ? -84.018  -22.323 -52.299 1.00 158.84 ? 170 GLY H C   1 
ATOM 3360 O O   . GLY C 3 170 ? -85.142  -21.821 -52.229 1.00 149.24 ? 170 GLY H O   1 
ATOM 3361 N N   . VAL C 3 171 ? -82.905  -21.611 -52.148 1.00 154.21 ? 171 VAL H N   1 
ATOM 3362 C CA  . VAL C 3 171 ? -82.901  -20.165 -51.962 1.00 151.48 ? 171 VAL H CA  1 
ATOM 3363 C C   . VAL C 3 171 ? -82.084  -19.542 -53.086 1.00 156.58 ? 171 VAL H C   1 
ATOM 3364 O O   . VAL C 3 171 ? -81.053  -20.089 -53.494 1.00 163.02 ? 171 VAL H O   1 
ATOM 3365 C CB  . VAL C 3 171 ? -82.352  -19.765 -50.574 1.00 155.52 ? 171 VAL H CB  1 
ATOM 3366 C CG1 . VAL C 3 171 ? -83.156  -20.443 -49.474 1.00 150.77 ? 171 VAL H CG1 1 
ATOM 3367 C CG2 . VAL C 3 171 ? -80.882  -20.128 -50.442 1.00 144.92 ? 171 VAL H CG2 1 
ATOM 3368 N N   . HIS C 3 172 ? -82.568  -18.417 -53.614 1.00 154.06 ? 172 HIS H N   1 
ATOM 3369 C CA  . HIS C 3 172 ? -81.941  -17.753 -54.757 1.00 155.06 ? 172 HIS H CA  1 
ATOM 3370 C C   . HIS C 3 172 ? -81.850  -16.259 -54.450 1.00 142.67 ? 172 HIS H C   1 
ATOM 3371 O O   . HIS C 3 172 ? -82.746  -15.487 -54.804 1.00 133.89 ? 172 HIS H O   1 
ATOM 3372 C CB  . HIS C 3 172 ? -82.735  -18.026 -56.036 1.00 162.61 ? 172 HIS H CB  1 
ATOM 3373 C CG  . HIS C 3 172 ? -82.776  -19.473 -56.423 1.00 165.66 ? 172 HIS H CG  1 
ATOM 3374 N ND1 . HIS C 3 172 ? -81.680  -20.304 -56.326 1.00 160.24 ? 172 HIS H ND1 1 
ATOM 3375 C CD2 . HIS C 3 172 ? -83.787  -20.240 -56.898 1.00 161.05 ? 172 HIS H CD2 1 
ATOM 3376 C CE1 . HIS C 3 172 ? -82.012  -21.518 -56.730 1.00 143.20 ? 172 HIS H CE1 1 
ATOM 3377 N NE2 . HIS C 3 172 ? -83.285  -21.506 -57.081 1.00 143.47 ? 172 HIS H NE2 1 
ATOM 3378 N N   . THR C 3 173 ? -80.767  -15.859 -53.788 1.00 143.95 ? 173 THR H N   1 
ATOM 3379 C CA  . THR C 3 173 ? -80.483  -14.459 -53.470 1.00 149.62 ? 173 THR H CA  1 
ATOM 3380 C C   . THR C 3 173 ? -78.997  -14.177 -53.684 1.00 143.08 ? 173 THR H C   1 
ATOM 3381 O O   . THR C 3 173 ? -78.326  -13.568 -52.849 1.00 156.01 ? 173 THR H O   1 
ATOM 3382 C CB  . THR C 3 173 ? -80.909  -14.111 -52.042 1.00 162.06 ? 173 THR H CB  1 
ATOM 3383 O OG1 . THR C 3 173 ? -80.428  -15.112 -51.136 1.00 163.20 ? 173 THR H OG1 1 
ATOM 3384 C CG2 . THR C 3 173 ? -82.428  -14.013 -51.935 1.00 144.97 ? 173 THR H CG2 1 
ATOM 3385 N N   . PHE C 3 174 ? -78.473  -14.623 -54.822 1.00 124.35 ? 174 PHE H N   1 
ATOM 3386 C CA  . PHE C 3 174 ? -77.037  -14.678 -55.042 1.00 123.53 ? 174 PHE H CA  1 
ATOM 3387 C C   . PHE C 3 174 ? -76.421  -13.279 -55.143 1.00 133.37 ? 174 PHE H C   1 
ATOM 3388 O O   . PHE C 3 174 ? -77.118  -12.295 -55.393 1.00 131.27 ? 174 PHE H O   1 
ATOM 3389 C CB  . PHE C 3 174 ? -76.742  -15.517 -56.284 1.00 123.52 ? 174 PHE H CB  1 
ATOM 3390 C CG  . PHE C 3 174 ? -76.899  -16.998 -56.060 1.00 125.89 ? 174 PHE H CG  1 
ATOM 3391 C CD1 . PHE C 3 174 ? -78.132  -17.542 -55.733 1.00 109.53 ? 174 PHE H CD1 1 
ATOM 3392 C CD2 . PHE C 3 174 ? -75.806  -17.845 -56.161 1.00 134.28 ? 174 PHE H CD2 1 
ATOM 3393 C CE1 . PHE C 3 174 ? -78.274  -18.900 -55.522 1.00 111.94 ? 174 PHE H CE1 1 
ATOM 3394 C CE2 . PHE C 3 174 ? -75.942  -19.205 -55.952 1.00 128.35 ? 174 PHE H CE2 1 
ATOM 3395 C CZ  . PHE C 3 174 ? -77.178  -19.732 -55.631 1.00 117.63 ? 174 PHE H CZ  1 
ATOM 3396 N N   . PRO C 3 175 ? -75.099  -13.180 -54.943 1.00 133.27 ? 175 PRO H N   1 
ATOM 3397 C CA  . PRO C 3 175 ? -74.486  -11.886 -54.572 1.00 135.45 ? 175 PRO H CA  1 
ATOM 3398 C C   . PRO C 3 175 ? -74.673  -10.722 -55.539 1.00 136.35 ? 175 PRO H C   1 
ATOM 3399 O O   . PRO C 3 175 ? -74.960  -9.610  -55.079 1.00 132.85 ? 175 PRO H O   1 
ATOM 3400 C CB  . PRO C 3 175 ? -73.008  -12.303 -54.446 1.00 135.50 ? 175 PRO H CB  1 
ATOM 3401 C CG  . PRO C 3 175 ? -72.956  -13.348 -55.544 1.00 117.32 ? 175 PRO H CG  1 
ATOM 3402 C CD  . PRO C 3 175 ? -74.026  -14.187 -54.961 1.00 109.74 ? 175 PRO H CD  1 
ATOM 3403 N N   . ALA C 3 176 ? -74.510  -10.929 -56.849 1.00 143.59 ? 176 ALA H N   1 
ATOM 3404 C CA  . ALA C 3 176 ? -74.516  -9.856  -57.851 1.00 139.69 ? 176 ALA H CA  1 
ATOM 3405 C C   . ALA C 3 176 ? -73.394  -8.843  -57.589 1.00 135.52 ? 176 ALA H C   1 
ATOM 3406 O O   . ALA C 3 176 ? -73.622  -7.673  -57.271 1.00 139.74 ? 176 ALA H O   1 
ATOM 3407 C CB  . ALA C 3 176 ? -75.885  -9.167  -57.916 1.00 132.49 ? 176 ALA H CB  1 
ATOM 3408 N N   . VAL C 3 177 ? -72.161  -9.334  -57.740 1.00 140.10 ? 177 VAL H N   1 
ATOM 3409 C CA  . VAL C 3 177 ? -70.965  -8.522  -57.542 1.00 147.83 ? 177 VAL H CA  1 
ATOM 3410 C C   . VAL C 3 177 ? -70.627  -7.787  -58.837 1.00 148.94 ? 177 VAL H C   1 
ATOM 3411 O O   . VAL C 3 177 ? -71.006  -8.199  -59.936 1.00 147.59 ? 177 VAL H O   1 
ATOM 3412 C CB  . VAL C 3 177 ? -69.781  -9.392  -57.061 1.00 151.10 ? 177 VAL H CB  1 
ATOM 3413 C CG1 . VAL C 3 177 ? -69.278  -10.293 -58.185 1.00 138.46 ? 177 VAL H CG1 1 
ATOM 3414 C CG2 . VAL C 3 177 ? -68.656  -8.530  -56.490 1.00 150.33 ? 177 VAL H CG2 1 
ATOM 3415 N N   . LEU C 3 178 ? -69.899  -6.678  -58.703 1.00 151.84 ? 178 LEU H N   1 
ATOM 3416 C CA  . LEU C 3 178 ? -69.535  -5.834  -59.832 1.00 147.23 ? 178 LEU H CA  1 
ATOM 3417 C C   . LEU C 3 178 ? -68.289  -6.366  -60.540 1.00 158.18 ? 178 LEU H C   1 
ATOM 3418 O O   . LEU C 3 178 ? -67.616  -7.289  -60.074 1.00 163.57 ? 178 LEU H O   1 
ATOM 3419 C CB  . LEU C 3 178 ? -69.298  -4.394  -59.373 1.00 140.61 ? 178 LEU H CB  1 
ATOM 3420 C CG  . LEU C 3 178 ? -67.909  -4.023  -58.846 1.00 144.31 ? 178 LEU H CG  1 
ATOM 3421 C CD1 . LEU C 3 178 ? -67.705  -2.517  -58.905 1.00 132.76 ? 178 LEU H CD1 1 
ATOM 3422 C CD2 . LEU C 3 178 ? -67.702  -4.538  -57.429 1.00 140.67 ? 178 LEU H CD2 1 
ATOM 3423 N N   . GLN C 3 179 ? -67.985  -5.760  -61.685 1.00 157.41 ? 179 GLN H N   1 
ATOM 3424 C CA  . GLN C 3 179 ? -66.798  -6.056  -62.477 1.00 159.57 ? 179 GLN H CA  1 
ATOM 3425 C C   . GLN C 3 179 ? -65.985  -4.780  -62.685 1.00 153.76 ? 179 GLN H C   1 
ATOM 3426 O O   . GLN C 3 179 ? -66.375  -3.689  -62.263 1.00 148.80 ? 179 GLN H O   1 
ATOM 3427 C CB  . GLN C 3 179 ? -67.174  -6.675  -63.827 1.00 150.61 ? 179 GLN H CB  1 
ATOM 3428 C CG  . GLN C 3 179 ? -67.650  -8.116  -63.760 1.00 155.49 ? 179 GLN H CG  1 
ATOM 3429 C CD  . GLN C 3 179 ? -67.877  -8.712  -65.137 1.00 149.36 ? 179 GLN H CD  1 
ATOM 3430 O OE1 . GLN C 3 179 ? -67.863  -8.002  -66.143 1.00 144.48 ? 179 GLN H OE1 1 
ATOM 3431 N NE2 . GLN C 3 179 ? -68.084  -10.024 -65.188 1.00 145.22 ? 179 GLN H NE2 1 
ATOM 3432 N N   . SER C 3 180 ? -64.837  -4.930  -63.352 1.00 154.32 ? 180 SER H N   1 
ATOM 3433 C CA  . SER C 3 180 ? -64.018  -3.781  -63.717 1.00 148.91 ? 180 SER H CA  1 
ATOM 3434 C C   . SER C 3 180 ? -64.627  -2.967  -64.851 1.00 145.46 ? 180 SER H C   1 
ATOM 3435 O O   . SER C 3 180 ? -64.148  -1.861  -65.125 1.00 143.18 ? 180 SER H O   1 
ATOM 3436 C CB  . SER C 3 180 ? -62.610  -4.239  -64.106 1.00 141.46 ? 180 SER H CB  1 
ATOM 3437 O OG  . SER C 3 180 ? -62.648  -5.182  -65.163 1.00 133.18 ? 180 SER H OG  1 
ATOM 3438 N N   . SER C 3 181 ? -65.664  -3.483  -65.508 1.00 151.41 ? 181 SER H N   1 
ATOM 3439 C CA  . SER C 3 181 ? -66.350  -2.789  -66.588 1.00 149.89 ? 181 SER H CA  1 
ATOM 3440 C C   . SER C 3 181 ? -67.527  -1.954  -66.097 1.00 144.25 ? 181 SER H C   1 
ATOM 3441 O O   . SER C 3 181 ? -68.286  -1.431  -66.919 1.00 138.67 ? 181 SER H O   1 
ATOM 3442 C CB  . SER C 3 181 ? -66.832  -3.795  -67.636 1.00 139.54 ? 181 SER H CB  1 
ATOM 3443 O OG  . SER C 3 181 ? -67.984  -4.489  -67.185 1.00 125.39 ? 181 SER H OG  1 
ATOM 3444 N N   . GLY C 3 182 ? -67.699  -1.824  -64.785 1.00 142.63 ? 182 GLY H N   1 
ATOM 3445 C CA  . GLY C 3 182 ? -68.836  -1.101  -64.245 1.00 131.12 ? 182 GLY H CA  1 
ATOM 3446 C C   . GLY C 3 182 ? -70.165  -1.766  -64.528 1.00 129.84 ? 182 GLY H C   1 
ATOM 3447 O O   . GLY C 3 182 ? -71.153  -1.075  -64.807 1.00 120.45 ? 182 GLY H O   1 
ATOM 3448 N N   . LEU C 3 183 ? -70.215  -3.094  -64.457 1.00 143.90 ? 183 LEU H N   1 
ATOM 3449 C CA  . LEU C 3 183 ? -71.421  -3.848  -64.785 1.00 138.62 ? 183 LEU H CA  1 
ATOM 3450 C C   . LEU C 3 183 ? -71.447  -5.089  -63.907 1.00 126.46 ? 183 LEU H C   1 
ATOM 3451 O O   . LEU C 3 183 ? -70.547  -5.929  -64.007 1.00 122.38 ? 183 LEU H O   1 
ATOM 3452 C CB  . LEU C 3 183 ? -71.435  -4.230  -66.268 1.00 134.13 ? 183 LEU H CB  1 
ATOM 3453 C CG  . LEU C 3 183 ? -71.836  -3.147  -67.275 1.00 105.92 ? 183 LEU H CG  1 
ATOM 3454 C CD1 . LEU C 3 183 ? -71.851  -3.701  -68.687 1.00 106.36 ? 183 LEU H CD1 1 
ATOM 3455 C CD2 . LEU C 3 183 ? -73.180  -2.534  -66.929 1.00 111.12 ? 183 LEU H CD2 1 
ATOM 3456 N N   . TYR C 3 184 ? -72.462  -5.209  -63.051 1.00 134.82 ? 184 TYR H N   1 
ATOM 3457 C CA  . TYR C 3 184 ? -72.495  -6.323  -62.114 1.00 148.60 ? 184 TYR H CA  1 
ATOM 3458 C C   . TYR C 3 184 ? -72.845  -7.622  -62.844 1.00 154.21 ? 184 TYR H C   1 
ATOM 3459 O O   . TYR C 3 184 ? -73.228  -7.629  -64.018 1.00 138.62 ? 184 TYR H O   1 
ATOM 3460 C CB  . TYR C 3 184 ? -73.511  -6.088  -60.991 1.00 133.59 ? 184 TYR H CB  1 
ATOM 3461 C CG  . TYR C 3 184 ? -73.589  -4.686  -60.414 1.00 124.80 ? 184 TYR H CG  1 
ATOM 3462 C CD1 . TYR C 3 184 ? -72.478  -3.854  -60.368 1.00 115.33 ? 184 TYR H CD1 1 
ATOM 3463 C CD2 . TYR C 3 184 ? -74.790  -4.200  -59.910 1.00 119.53 ? 184 TYR H CD2 1 
ATOM 3464 C CE1 . TYR C 3 184 ? -72.561  -2.578  -59.840 1.00 105.47 ? 184 TYR H CE1 1 
ATOM 3465 C CE2 . TYR C 3 184 ? -74.884  -2.929  -59.381 1.00 110.42 ? 184 TYR H CE2 1 
ATOM 3466 C CZ  . TYR C 3 184 ? -73.768  -2.121  -59.348 1.00 115.94 ? 184 TYR H CZ  1 
ATOM 3467 O OH  . TYR C 3 184 ? -73.862  -0.854  -58.819 1.00 125.41 ? 184 TYR H OH  1 
ATOM 3468 N N   . SER C 3 185 ? -72.714  -8.734  -62.121 1.00 156.63 ? 185 SER H N   1 
ATOM 3469 C CA  . SER C 3 185 ? -73.031  -10.051 -62.663 1.00 149.98 ? 185 SER H CA  1 
ATOM 3470 C C   . SER C 3 185 ? -73.175  -11.031 -61.509 1.00 149.72 ? 185 SER H C   1 
ATOM 3471 O O   . SER C 3 185 ? -72.291  -11.108 -60.651 1.00 154.40 ? 185 SER H O   1 
ATOM 3472 C CB  . SER C 3 185 ? -71.943  -10.525 -63.634 1.00 148.72 ? 185 SER H CB  1 
ATOM 3473 O OG  . SER C 3 185 ? -70.671  -10.531 -63.008 1.00 151.43 ? 185 SER H OG  1 
ATOM 3474 N N   . LEU C 3 186 ? -74.278  -11.775 -61.490 1.00 147.58 ? 186 LEU H N   1 
ATOM 3475 C CA  . LEU C 3 186 ? -74.524  -12.777 -60.463 1.00 143.69 ? 186 LEU H CA  1 
ATOM 3476 C C   . LEU C 3 186 ? -74.659  -14.156 -61.093 1.00 144.51 ? 186 LEU H C   1 
ATOM 3477 O O   . LEU C 3 186 ? -74.758  -14.308 -62.313 1.00 160.72 ? 186 LEU H O   1 
ATOM 3478 C CB  . LEU C 3 186 ? -75.781  -12.452 -59.641 1.00 142.90 ? 186 LEU H CB  1 
ATOM 3479 C CG  . LEU C 3 186 ? -77.167  -12.933 -60.075 1.00 138.69 ? 186 LEU H CG  1 
ATOM 3480 C CD1 . LEU C 3 186 ? -78.194  -12.582 -59.012 1.00 133.58 ? 186 LEU H CD1 1 
ATOM 3481 C CD2 . LEU C 3 186 ? -77.563  -12.321 -61.393 1.00 151.63 ? 186 LEU H CD2 1 
ATOM 3482 N N   . SER C 3 187 ? -74.658  -15.166 -60.233 1.00 144.00 ? 187 SER H N   1 
ATOM 3483 C CA  . SER C 3 187 ? -74.880  -16.552 -60.615 1.00 148.70 ? 187 SER H CA  1 
ATOM 3484 C C   . SER C 3 187 ? -76.129  -17.066 -59.897 1.00 145.65 ? 187 SER H C   1 
ATOM 3485 O O   . SER C 3 187 ? -76.876  -16.301 -59.281 1.00 149.71 ? 187 SER H O   1 
ATOM 3486 C CB  . SER C 3 187 ? -73.644  -17.400 -60.302 1.00 154.49 ? 187 SER H CB  1 
ATOM 3487 O OG  . SER C 3 187 ? -72.493  -16.885 -60.953 1.00 132.73 ? 187 SER H OG  1 
ATOM 3488 N N   . SER C 3 188 ? -76.361  -18.371 -60.002 1.00 145.22 ? 188 SER H N   1 
ATOM 3489 C CA  . SER C 3 188 ? -77.458  -19.049 -59.323 1.00 141.76 ? 188 SER H CA  1 
ATOM 3490 C C   . SER C 3 188 ? -77.234  -20.547 -59.452 1.00 159.31 ? 188 SER H C   1 
ATOM 3491 O O   . SER C 3 188 ? -76.671  -21.011 -60.446 1.00 188.19 ? 188 SER H O   1 
ATOM 3492 C CB  . SER C 3 188 ? -78.824  -18.658 -59.908 1.00 128.67 ? 188 SER H CB  1 
ATOM 3493 O OG  . SER C 3 188 ? -79.399  -17.574 -59.198 1.00 117.32 ? 188 SER H OG  1 
ATOM 3494 N N   . VAL C 3 189 ? -77.661  -21.294 -58.436 1.00 157.57 ? 189 VAL H N   1 
ATOM 3495 C CA  . VAL C 3 189 ? -77.532  -22.747 -58.424 1.00 150.43 ? 189 VAL H CA  1 
ATOM 3496 C C   . VAL C 3 189 ? -78.850  -23.364 -57.987 1.00 155.51 ? 189 VAL H C   1 
ATOM 3497 O O   . VAL C 3 189 ? -79.397  -22.998 -56.941 1.00 148.60 ? 189 VAL H O   1 
ATOM 3498 C CB  . VAL C 3 189 ? -76.387  -23.218 -57.506 1.00 132.82 ? 189 VAL H CB  1 
ATOM 3499 C CG1 . VAL C 3 189 ? -76.594  -24.663 -57.088 1.00 128.15 ? 189 VAL H CG1 1 
ATOM 3500 C CG2 . VAL C 3 189 ? -75.080  -23.099 -58.231 1.00 125.50 ? 189 VAL H CG2 1 
ATOM 3501 N N   . VAL C 3 190 ? -79.355  -24.299 -58.788 1.00 184.24 ? 190 VAL H N   1 
ATOM 3502 C CA  . VAL C 3 190 ? -80.445  -25.180 -58.393 1.00 191.91 ? 190 VAL H CA  1 
ATOM 3503 C C   . VAL C 3 190 ? -79.909  -26.606 -58.398 1.00 192.70 ? 190 VAL H C   1 
ATOM 3504 O O   . VAL C 3 190 ? -79.300  -27.047 -59.382 1.00 193.44 ? 190 VAL H O   1 
ATOM 3505 C CB  . VAL C 3 190 ? -81.677  -25.027 -59.308 1.00 195.65 ? 190 VAL H CB  1 
ATOM 3506 C CG1 . VAL C 3 190 ? -81.296  -25.145 -60.775 1.00 191.35 ? 190 VAL H CG1 1 
ATOM 3507 C CG2 . VAL C 3 190 ? -82.741  -26.054 -58.946 1.00 197.04 ? 190 VAL H CG2 1 
ATOM 3508 N N   . THR C 3 191 ? -80.102  -27.307 -57.284 1.00 190.91 ? 191 THR H N   1 
ATOM 3509 C CA  . THR C 3 191 ? -79.591  -28.655 -57.090 1.00 180.13 ? 191 THR H CA  1 
ATOM 3510 C C   . THR C 3 191 ? -80.758  -29.623 -56.962 1.00 185.40 ? 191 THR H C   1 
ATOM 3511 O O   . THR C 3 191 ? -81.795  -29.287 -56.381 1.00 193.96 ? 191 THR H O   1 
ATOM 3512 C CB  . THR C 3 191 ? -78.699  -28.740 -55.843 1.00 176.99 ? 191 THR H CB  1 
ATOM 3513 O OG1 . THR C 3 191 ? -77.895  -27.557 -55.746 1.00 174.94 ? 191 THR H OG1 1 
ATOM 3514 C CG2 . THR C 3 191 ? -77.788  -29.957 -55.917 1.00 171.31 ? 191 THR H CG2 1 
ATOM 3515 N N   . VAL C 3 192 ? -80.585  -30.821 -57.510 1.00 182.18 ? 192 VAL H N   1 
ATOM 3516 C CA  . VAL C 3 192 ? -81.654  -31.816 -57.531 1.00 173.52 ? 192 VAL H CA  1 
ATOM 3517 C C   . VAL C 3 192 ? -81.011  -33.197 -57.612 1.00 169.86 ? 192 VAL H C   1 
ATOM 3518 O O   . VAL C 3 192 ? -79.868  -33.313 -58.080 1.00 175.50 ? 192 VAL H O   1 
ATOM 3519 C CB  . VAL C 3 192 ? -82.616  -31.556 -58.705 1.00 155.98 ? 192 VAL H CB  1 
ATOM 3520 C CG1 . VAL C 3 192 ? -81.964  -31.922 -60.034 1.00 164.11 ? 192 VAL H CG1 1 
ATOM 3521 C CG2 . VAL C 3 192 ? -83.946  -32.281 -58.518 1.00 154.07 ? 192 VAL H CG2 1 
ATOM 3522 N N   . PRO C 3 193 ? -81.672  -34.257 -57.147 1.00 160.77 ? 193 PRO H N   1 
ATOM 3523 C CA  . PRO C 3 193 ? -81.170  -35.607 -57.416 1.00 164.14 ? 193 PRO H CA  1 
ATOM 3524 C C   . PRO C 3 193 ? -80.921  -35.821 -58.904 1.00 161.21 ? 193 PRO H C   1 
ATOM 3525 O O   . PRO C 3 193 ? -81.705  -35.393 -59.754 1.00 165.61 ? 193 PRO H O   1 
ATOM 3526 C CB  . PRO C 3 193 ? -82.296  -36.499 -56.893 1.00 164.97 ? 193 PRO H CB  1 
ATOM 3527 C CG  . PRO C 3 193 ? -82.817  -35.737 -55.714 1.00 141.43 ? 193 PRO H CG  1 
ATOM 3528 C CD  . PRO C 3 193 ? -82.657  -34.261 -56.047 1.00 146.65 ? 193 PRO H CD  1 
ATOM 3529 N N   . SER C 3 194 ? -79.804  -36.488 -59.212 1.00 156.38 ? 194 SER H N   1 
ATOM 3530 C CA  . SER C 3 194 ? -79.318  -36.573 -60.586 1.00 162.76 ? 194 SER H CA  1 
ATOM 3531 C C   . SER C 3 194 ? -80.278  -37.308 -61.514 1.00 177.46 ? 194 SER H C   1 
ATOM 3532 O O   . SER C 3 194 ? -80.247  -37.069 -62.727 1.00 172.51 ? 194 SER H O   1 
ATOM 3533 C CB  . SER C 3 194 ? -77.950  -37.259 -60.615 1.00 158.98 ? 194 SER H CB  1 
ATOM 3534 O OG  . SER C 3 194 ? -76.998  -36.540 -59.851 1.00 160.16 ? 194 SER H OG  1 
ATOM 3535 N N   . SER C 3 195 ? -81.124  -38.192 -60.978 1.00 186.43 ? 195 SER H N   1 
ATOM 3536 C CA  . SER C 3 195 ? -82.025  -38.966 -61.829 1.00 176.78 ? 195 SER H CA  1 
ATOM 3537 C C   . SER C 3 195 ? -82.970  -38.058 -62.606 1.00 179.88 ? 195 SER H C   1 
ATOM 3538 O O   . SER C 3 195 ? -83.158  -38.232 -63.818 1.00 174.99 ? 195 SER H O   1 
ATOM 3539 C CB  . SER C 3 195 ? -82.814  -39.963 -60.981 1.00 160.68 ? 195 SER H CB  1 
ATOM 3540 O OG  . SER C 3 195 ? -81.946  -40.777 -60.211 1.00 151.99 ? 195 SER H OG  1 
ATOM 3541 N N   . SER C 3 196 ? -83.548  -37.061 -61.933 1.00 189.68 ? 196 SER H N   1 
ATOM 3542 C CA  . SER C 3 196 ? -84.435  -36.112 -62.594 1.00 182.16 ? 196 SER H CA  1 
ATOM 3543 C C   . SER C 3 196 ? -83.732  -35.314 -63.685 1.00 175.24 ? 196 SER H C   1 
ATOM 3544 O O   . SER C 3 196 ? -84.401  -34.568 -64.409 1.00 175.04 ? 196 SER H O   1 
ATOM 3545 C CB  . SER C 3 196 ? -85.048  -35.162 -61.562 1.00 189.49 ? 196 SER H CB  1 
ATOM 3546 O OG  . SER C 3 196 ? -85.795  -35.877 -60.592 1.00 184.67 ? 196 SER H OG  1 
ATOM 3547 N N   . LEU C 3 197 ? -82.409  -35.446 -63.818 1.00 173.52 ? 197 LEU H N   1 
ATOM 3548 C CA  . LEU C 3 197 ? -81.718  -34.853 -64.957 1.00 163.07 ? 197 LEU H CA  1 
ATOM 3549 C C   . LEU C 3 197 ? -82.222  -35.427 -66.273 1.00 171.17 ? 197 LEU H C   1 
ATOM 3550 O O   . LEU C 3 197 ? -82.226  -34.730 -67.294 1.00 168.63 ? 197 LEU H O   1 
ATOM 3551 C CB  . LEU C 3 197 ? -80.210  -35.074 -64.834 1.00 152.69 ? 197 LEU H CB  1 
ATOM 3552 C CG  . LEU C 3 197 ? -79.386  -34.009 -64.111 1.00 151.57 ? 197 LEU H CG  1 
ATOM 3553 C CD1 . LEU C 3 197 ? -77.943  -34.468 -63.979 1.00 146.20 ? 197 LEU H CD1 1 
ATOM 3554 C CD2 . LEU C 3 197 ? -79.462  -32.682 -64.847 1.00 146.71 ? 197 LEU H CD2 1 
ATOM 3555 N N   . GLY C 3 198 ? -82.652  -36.690 -66.271 1.00 180.15 ? 198 GLY H N   1 
ATOM 3556 C CA  . GLY C 3 198 ? -83.084  -37.334 -67.496 1.00 176.63 ? 198 GLY H CA  1 
ATOM 3557 C C   . GLY C 3 198 ? -84.522  -37.103 -67.906 1.00 172.67 ? 198 GLY H C   1 
ATOM 3558 O O   . GLY C 3 198 ? -84.888  -37.445 -69.034 1.00 156.70 ? 198 GLY H O   1 
ATOM 3559 N N   . THR C 3 199 ? -85.352  -36.532 -67.032 1.00 181.40 ? 199 THR H N   1 
ATOM 3560 C CA  . THR C 3 199 ? -86.773  -36.383 -67.320 1.00 180.38 ? 199 THR H CA  1 
ATOM 3561 C C   . THR C 3 199 ? -87.355  -35.013 -67.001 1.00 182.63 ? 199 THR H C   1 
ATOM 3562 O O   . THR C 3 199 ? -88.399  -34.669 -67.569 1.00 182.22 ? 199 THR H O   1 
ATOM 3563 C CB  . THR C 3 199 ? -87.587  -37.440 -66.558 1.00 183.35 ? 199 THR H CB  1 
ATOM 3564 O OG1 . THR C 3 199 ? -88.983  -37.124 -66.639 1.00 184.10 ? 199 THR H OG1 1 
ATOM 3565 C CG2 . THR C 3 199 ? -87.166  -37.485 -65.097 1.00 181.20 ? 199 THR H CG2 1 
ATOM 3566 N N   . GLN C 3 200 ? -86.736  -34.224 -66.128 1.00 191.07 ? 200 GLN H N   1 
ATOM 3567 C CA  . GLN C 3 200 ? -87.310  -32.964 -65.676 1.00 188.44 ? 200 GLN H CA  1 
ATOM 3568 C C   . GLN C 3 200 ? -86.678  -31.790 -66.413 1.00 184.95 ? 200 GLN H C   1 
ATOM 3569 O O   . GLN C 3 200 ? -85.459  -31.742 -66.600 1.00 189.89 ? 200 GLN H O   1 
ATOM 3570 C CB  . GLN C 3 200 ? -87.125  -32.792 -64.167 1.00 175.45 ? 200 GLN H CB  1 
ATOM 3571 C CG  . GLN C 3 200 ? -88.234  -32.000 -63.491 1.00 164.94 ? 200 GLN H CG  1 
ATOM 3572 C CD  . GLN C 3 200 ? -89.466  -32.840 -63.210 1.00 155.24 ? 200 GLN H CD  1 
ATOM 3573 O OE1 . GLN C 3 200 ? -89.414  -34.070 -63.239 1.00 158.99 ? 200 GLN H OE1 1 
ATOM 3574 N NE2 . GLN C 3 200 ? -90.584  -32.177 -62.940 1.00 142.84 ? 200 GLN H NE2 1 
ATOM 3575 N N   . THR C 3 201 ? -87.518  -30.845 -66.829 1.00 178.16 ? 201 THR H N   1 
ATOM 3576 C CA  . THR C 3 201 ? -87.058  -29.636 -67.497 1.00 173.51 ? 201 THR H CA  1 
ATOM 3577 C C   . THR C 3 201 ? -86.728  -28.560 -66.470 1.00 185.11 ? 201 THR H C   1 
ATOM 3578 O O   . THR C 3 201 ? -87.455  -28.373 -65.490 1.00 183.02 ? 201 THR H O   1 
ATOM 3579 C CB  . THR C 3 201 ? -88.113  -29.122 -68.482 1.00 156.35 ? 201 THR H CB  1 
ATOM 3580 O OG1 . THR C 3 201 ? -87.701  -27.856 -69.012 1.00 159.75 ? 201 THR H OG1 1 
ATOM 3581 C CG2 . THR C 3 201 ? -89.470  -28.975 -67.803 1.00 144.90 ? 201 THR H CG2 1 
ATOM 3582 N N   . TYR C 3 202 ? -85.618  -27.863 -66.696 1.00 188.44 ? 202 TYR H N   1 
ATOM 3583 C CA  . TYR C 3 202 ? -85.134  -26.823 -65.791 1.00 176.59 ? 202 TYR H CA  1 
ATOM 3584 C C   . TYR C 3 202 ? -85.323  -25.466 -66.461 1.00 188.66 ? 202 TYR H C   1 
ATOM 3585 O O   . TYR C 3 202 ? -84.476  -25.026 -67.245 1.00 193.20 ? 202 TYR H O   1 
ATOM 3586 C CB  . TYR C 3 202 ? -83.675  -27.065 -65.417 1.00 158.81 ? 202 TYR H CB  1 
ATOM 3587 C CG  . TYR C 3 202 ? -83.414  -28.445 -64.862 1.00 157.29 ? 202 TYR H CG  1 
ATOM 3588 C CD1 . TYR C 3 202 ? -83.931  -28.825 -63.631 1.00 162.05 ? 202 TYR H CD1 1 
ATOM 3589 C CD2 . TYR C 3 202 ? -82.654  -29.367 -65.568 1.00 167.28 ? 202 TYR H CD2 1 
ATOM 3590 C CE1 . TYR C 3 202 ? -83.697  -30.085 -63.118 1.00 170.74 ? 202 TYR H CE1 1 
ATOM 3591 C CE2 . TYR C 3 202 ? -82.414  -30.630 -65.062 1.00 171.38 ? 202 TYR H CE2 1 
ATOM 3592 C CZ  . TYR C 3 202 ? -82.939  -30.983 -63.836 1.00 179.58 ? 202 TYR H CZ  1 
ATOM 3593 O OH  . TYR C 3 202 ? -82.705  -32.238 -63.325 1.00 185.27 ? 202 TYR H OH  1 
ATOM 3594 N N   . ILE C 3 203 ? -86.435  -24.810 -66.146 1.00 188.07 ? 203 ILE H N   1 
ATOM 3595 C CA  . ILE C 3 203 ? -86.729  -23.465 -66.626 1.00 183.15 ? 203 ILE H CA  1 
ATOM 3596 C C   . ILE C 3 203 ? -86.467  -22.501 -65.476 1.00 177.48 ? 203 ILE H C   1 
ATOM 3597 O O   . ILE C 3 203 ? -87.230  -22.449 -64.505 1.00 170.09 ? 203 ILE H O   1 
ATOM 3598 C CB  . ILE C 3 203 ? -88.169  -23.351 -67.147 1.00 178.90 ? 203 ILE H CB  1 
ATOM 3599 C CG1 . ILE C 3 203 ? -89.135  -24.132 -66.250 1.00 168.06 ? 203 ILE H CG1 1 
ATOM 3600 C CG2 . ILE C 3 203 ? -88.253  -23.842 -68.586 1.00 166.56 ? 203 ILE H CG2 1 
ATOM 3601 C CD1 . ILE C 3 203 ? -90.560  -24.160 -66.760 1.00 163.32 ? 203 ILE H CD1 1 
ATOM 3602 N N   . CYS C 3 204 ? -85.385  -21.736 -65.579 1.00 187.80 ? 204 CYS H N   1 
ATOM 3603 C CA  . CYS C 3 204 ? -84.964  -20.828 -64.524 1.00 194.49 ? 204 CYS H CA  1 
ATOM 3604 C C   . CYS C 3 204 ? -85.313  -19.391 -64.884 1.00 191.06 ? 204 CYS H C   1 
ATOM 3605 O O   . CYS C 3 204 ? -85.129  -18.957 -66.029 1.00 184.51 ? 204 CYS H O   1 
ATOM 3606 C CB  . CYS C 3 204 ? -83.460  -20.944 -64.264 1.00 191.91 ? 204 CYS H CB  1 
ATOM 3607 S SG  . CYS C 3 204 ? -82.412  -20.627 -65.706 1.00 212.29 ? 204 CYS H SG  1 
ATOM 3608 N N   . ASN C 3 205 ? -85.834  -18.665 -63.899 1.00 183.99 ? 205 ASN H N   1 
ATOM 3609 C CA  . ASN C 3 205 ? -86.021  -17.231 -64.022 1.00 173.62 ? 205 ASN H CA  1 
ATOM 3610 C C   . ASN C 3 205 ? -84.670  -16.527 -63.979 1.00 179.44 ? 205 ASN H C   1 
ATOM 3611 O O   . ASN C 3 205 ? -83.690  -17.040 -63.430 1.00 178.60 ? 205 ASN H O   1 
ATOM 3612 C CB  . ASN C 3 205 ? -86.907  -16.703 -62.895 1.00 164.92 ? 205 ASN H CB  1 
ATOM 3613 C CG  . ASN C 3 205 ? -88.112  -17.581 -62.640 1.00 167.00 ? 205 ASN H CG  1 
ATOM 3614 O OD1 . ASN C 3 205 ? -89.186  -17.348 -63.186 1.00 167.23 ? 205 ASN H OD1 1 
ATOM 3615 N ND2 . ASN C 3 205 ? -87.940  -18.596 -61.800 1.00 173.16 ? 205 ASN H ND2 1 
ATOM 3616 N N   . VAL C 3 206 ? -84.621  -15.333 -64.563 1.00 180.12 ? 206 VAL H N   1 
ATOM 3617 C CA  . VAL C 3 206 ? -83.431  -14.495 -64.503 1.00 175.86 ? 206 VAL H CA  1 
ATOM 3618 C C   . VAL C 3 206 ? -83.863  -13.056 -64.262 1.00 176.19 ? 206 VAL H C   1 
ATOM 3619 O O   . VAL C 3 206 ? -84.830  -12.576 -64.862 1.00 180.04 ? 206 VAL H O   1 
ATOM 3620 C CB  . VAL C 3 206 ? -82.586  -14.604 -65.787 1.00 173.43 ? 206 VAL H CB  1 
ATOM 3621 C CG1 . VAL C 3 206 ? -81.617  -13.453 -65.855 1.00 178.92 ? 206 VAL H CG1 1 
ATOM 3622 C CG2 . VAL C 3 206 ? -81.839  -15.930 -65.826 1.00 162.89 ? 206 VAL H CG2 1 
ATOM 3623 N N   . ASN C 3 207 ? -83.143  -12.372 -63.375 1.00 182.31 ? 207 ASN H N   1 
ATOM 3624 C CA  . ASN C 3 207 ? -83.428  -10.977 -63.079 1.00 192.27 ? 207 ASN H CA  1 
ATOM 3625 C C   . ASN C 3 207 ? -83.259  -10.111 -64.324 1.00 200.89 ? 207 ASN H C   1 
ATOM 3626 O O   . ASN C 3 207 ? -82.279  -10.249 -65.063 1.00 204.67 ? 207 ASN H O   1 
ATOM 3627 C CB  . ASN C 3 207 ? -82.498  -10.490 -61.967 1.00 192.20 ? 207 ASN H CB  1 
ATOM 3628 C CG  . ASN C 3 207 ? -82.687  -11.253 -60.667 1.00 183.73 ? 207 ASN H CG  1 
ATOM 3629 O OD1 . ASN C 3 207 ? -83.346  -12.293 -60.633 1.00 182.72 ? 207 ASN H OD1 1 
ATOM 3630 N ND2 . ASN C 3 207 ? -82.102  -10.741 -59.590 1.00 163.81 ? 207 ASN H ND2 1 
ATOM 3631 N N   . HIS C 3 208 ? -84.222  -9.219  -64.556 1.00 202.85 ? 208 HIS H N   1 
ATOM 3632 C CA  . HIS C 3 208 ? -84.138  -8.204  -65.597 1.00 192.27 ? 208 HIS H CA  1 
ATOM 3633 C C   . HIS C 3 208 ? -84.017  -6.825  -64.960 1.00 181.67 ? 208 HIS H C   1 
ATOM 3634 O O   . HIS C 3 208 ? -84.547  -6.574  -63.875 1.00 176.07 ? 208 HIS H O   1 
ATOM 3635 C CB  . HIS C 3 208 ? -85.351  -8.249  -66.528 1.00 186.58 ? 208 HIS H CB  1 
ATOM 3636 C CG  . HIS C 3 208 ? -85.024  -7.952  -67.960 1.00 180.65 ? 208 HIS H CG  1 
ATOM 3637 N ND1 . HIS C 3 208 ? -85.397  -8.779  -68.997 1.00 177.16 ? 208 HIS H ND1 1 
ATOM 3638 C CD2 . HIS C 3 208 ? -84.367  -6.912  -68.527 1.00 171.44 ? 208 HIS H CD2 1 
ATOM 3639 C CE1 . HIS C 3 208 ? -84.977  -8.266  -70.140 1.00 174.72 ? 208 HIS H CE1 1 
ATOM 3640 N NE2 . HIS C 3 208 ? -84.350  -7.133  -69.882 1.00 172.57 ? 208 HIS H NE2 1 
ATOM 3641 N N   . LYS C 3 209 ? -83.340  -5.924  -65.665 1.00 180.20 ? 209 LYS H N   1 
ATOM 3642 C CA  . LYS C 3 209 ? -82.677  -4.801  -65.009 1.00 168.90 ? 209 LYS H CA  1 
ATOM 3643 C C   . LYS C 3 209 ? -83.563  -3.620  -64.612 1.00 164.56 ? 209 LYS H C   1 
ATOM 3644 O O   . LYS C 3 209 ? -83.428  -3.138  -63.481 1.00 160.77 ? 209 LYS H O   1 
ATOM 3645 C CB  . LYS C 3 209 ? -81.525  -4.318  -65.891 1.00 168.48 ? 209 LYS H CB  1 
ATOM 3646 C CG  . LYS C 3 209 ? -80.344  -5.248  -65.816 1.00 165.35 ? 209 LYS H CG  1 
ATOM 3647 C CD  . LYS C 3 209 ? -80.050  -5.606  -64.377 1.00 164.58 ? 209 LYS H CD  1 
ATOM 3648 C CE  . LYS C 3 209 ? -79.671  -7.068  -64.272 1.00 174.28 ? 209 LYS H CE  1 
ATOM 3649 N NZ  . LYS C 3 209 ? -80.857  -7.964  -64.335 1.00 194.35 ? 209 LYS H NZ  1 
ATOM 3650 N N   . PRO C 3 210 ? -84.449  -3.086  -65.487 1.00 171.45 ? 210 PRO H N   1 
ATOM 3651 C CA  . PRO C 3 210 ? -85.218  -1.898  -65.080 1.00 160.79 ? 210 PRO H CA  1 
ATOM 3652 C C   . PRO C 3 210 ? -86.030  -2.107  -63.809 1.00 163.38 ? 210 PRO H C   1 
ATOM 3653 O O   . PRO C 3 210 ? -85.751  -1.466  -62.790 1.00 155.85 ? 210 PRO H O   1 
ATOM 3654 C CB  . PRO C 3 210 ? -86.132  -1.642  -66.283 1.00 142.39 ? 210 PRO H CB  1 
ATOM 3655 C CG  . PRO C 3 210 ? -85.405  -2.207  -67.436 1.00 127.46 ? 210 PRO H CG  1 
ATOM 3656 C CD  . PRO C 3 210 ? -84.620  -3.380  -66.924 1.00 156.13 ? 210 PRO H CD  1 
ATOM 3657 N N   . SER C 3 211 ? -86.983  -3.044  -63.852 1.00 172.41 ? 211 SER H N   1 
ATOM 3658 C CA  . SER C 3 211 ? -87.873  -3.394  -62.745 1.00 169.28 ? 211 SER H CA  1 
ATOM 3659 C C   . SER C 3 211 ? -89.020  -4.252  -63.262 1.00 178.40 ? 211 SER H C   1 
ATOM 3660 O O   . SER C 3 211 ? -89.374  -5.264  -62.649 1.00 171.79 ? 211 SER H O   1 
ATOM 3661 C CB  . SER C 3 211 ? -88.443  -2.156  -62.042 1.00 164.38 ? 211 SER H CB  1 
ATOM 3662 O OG  . SER C 3 211 ? -88.948  -1.219  -62.976 1.00 171.30 ? 211 SER H OG  1 
ATOM 3663 N N   . ASN C 3 212 ? -89.602  -3.850  -64.391 1.00 184.61 ? 212 ASN H N   1 
ATOM 3664 C CA  . ASN C 3 212 ? -90.771  -4.503  -64.983 1.00 180.12 ? 212 ASN H CA  1 
ATOM 3665 C C   . ASN C 3 212 ? -90.386  -5.057  -66.353 1.00 185.45 ? 212 ASN H C   1 
ATOM 3666 O O   . ASN C 3 212 ? -90.617  -4.424  -67.387 1.00 180.87 ? 212 ASN H O   1 
ATOM 3667 C CB  . ASN C 3 212 ? -91.935  -3.508  -65.070 1.00 164.59 ? 212 ASN H CB  1 
ATOM 3668 C CG  . ASN C 3 212 ? -91.483  -2.115  -65.479 1.00 149.59 ? 212 ASN H CG  1 
ATOM 3669 O OD1 . ASN C 3 212 ? -90.370  -1.930  -65.974 1.00 146.99 ? 212 ASN H OD1 1 
ATOM 3670 N ND2 . ASN C 3 212 ? -92.345  -1.129  -65.268 1.00 125.72 ? 212 ASN H ND2 1 
ATOM 3671 N N   . THR C 3 213 ? -89.812  -6.260  -66.343 1.00 193.80 ? 213 THR H N   1 
ATOM 3672 C CA  . THR C 3 213 ? -89.350  -7.014  -67.506 1.00 195.42 ? 213 THR H CA  1 
ATOM 3673 C C   . THR C 3 213 ? -88.721  -8.299  -66.975 1.00 198.04 ? 213 THR H C   1 
ATOM 3674 O O   . THR C 3 213 ? -88.450  -8.423  -65.777 1.00 193.73 ? 213 THR H O   1 
ATOM 3675 C CB  . THR C 3 213 ? -88.372  -6.214  -68.377 1.00 183.14 ? 213 THR H CB  1 
ATOM 3676 O OG1 . THR C 3 213 ? -87.775  -7.069  -69.362 1.00 191.72 ? 213 THR H OG1 1 
ATOM 3677 C CG2 . THR C 3 213 ? -87.308  -5.535  -67.529 1.00 166.51 ? 213 THR H CG2 1 
ATOM 3678 N N   . LYS C 3 214 ? -88.492  -9.256  -67.875 1.00 199.87 ? 214 LYS H N   1 
ATOM 3679 C CA  . LYS C 3 214 ? -88.148  -10.605 -67.443 1.00 190.16 ? 214 LYS H CA  1 
ATOM 3680 C C   . LYS C 3 214 ? -87.333  -11.327 -68.507 1.00 183.37 ? 214 LYS H C   1 
ATOM 3681 O O   . LYS C 3 214 ? -87.414  -11.011 -69.698 1.00 183.00 ? 214 LYS H O   1 
ATOM 3682 C CB  . LYS C 3 214 ? -89.419  -11.407 -67.130 1.00 178.11 ? 214 LYS H CB  1 
ATOM 3683 C CG  . LYS C 3 214 ? -89.192  -12.776 -66.509 1.00 168.76 ? 214 LYS H CG  1 
ATOM 3684 C CD  . LYS C 3 214 ? -89.450  -13.886 -67.515 1.00 163.58 ? 214 LYS H CD  1 
ATOM 3685 C CE  . LYS C 3 214 ? -90.884  -13.861 -68.016 1.00 163.21 ? 214 LYS H CE  1 
ATOM 3686 N NZ  . LYS C 3 214 ? -91.196  -15.043 -68.866 1.00 168.24 ? 214 LYS H NZ  1 
ATOM 3687 N N   . VAL C 3 215 ? -86.537  -12.300 -68.056 1.00 179.03 ? 215 VAL H N   1 
ATOM 3688 C CA  . VAL C 3 215 ? -85.934  -13.312 -68.916 1.00 174.09 ? 215 VAL H CA  1 
ATOM 3689 C C   . VAL C 3 215 ? -86.153  -14.678 -68.278 1.00 172.03 ? 215 VAL H C   1 
ATOM 3690 O O   . VAL C 3 215 ? -86.040  -14.832 -67.056 1.00 175.50 ? 215 VAL H O   1 
ATOM 3691 C CB  . VAL C 3 215 ? -84.426  -13.077 -69.155 1.00 167.18 ? 215 VAL H CB  1 
ATOM 3692 C CG1 . VAL C 3 215 ? -83.931  -13.997 -70.258 1.00 149.04 ? 215 VAL H CG1 1 
ATOM 3693 C CG2 . VAL C 3 215 ? -84.145  -11.634 -69.515 1.00 163.39 ? 215 VAL H CG2 1 
ATOM 3694 N N   . ASP C 3 216 ? -86.477  -15.666 -69.106 1.00 170.87 ? 216 ASP H N   1 
ATOM 3695 C CA  . ASP C 3 216 ? -86.559  -17.059 -68.694 1.00 177.18 ? 216 ASP H CA  1 
ATOM 3696 C C   . ASP C 3 216 ? -85.609  -17.879 -69.555 1.00 181.06 ? 216 ASP H C   1 
ATOM 3697 O O   . ASP C 3 216 ? -85.375  -17.551 -70.722 1.00 186.65 ? 216 ASP H O   1 
ATOM 3698 C CB  . ASP C 3 216 ? -87.988  -17.603 -68.828 1.00 177.19 ? 216 ASP H CB  1 
ATOM 3699 C CG  . ASP C 3 216 ? -88.800  -17.433 -67.559 1.00 183.05 ? 216 ASP H CG  1 
ATOM 3700 O OD1 . ASP C 3 216 ? -88.242  -17.642 -66.461 1.00 195.10 ? 216 ASP H OD1 1 
ATOM 3701 O OD2 . ASP C 3 216 ? -89.999  -17.096 -67.659 1.00 171.39 ? 216 ASP H OD2 1 
ATOM 3702 N N   . LYS C 3 217 ? -85.049  -18.943 -68.981 1.00 185.48 ? 217 LYS H N   1 
ATOM 3703 C CA  . LYS C 3 217 ? -84.124  -19.776 -69.740 1.00 189.24 ? 217 LYS H CA  1 
ATOM 3704 C C   . LYS C 3 217 ? -84.316  -21.245 -69.396 1.00 195.21 ? 217 LYS H C   1 
ATOM 3705 O O   . LYS C 3 217 ? -84.278  -21.621 -68.223 1.00 194.54 ? 217 LYS H O   1 
ATOM 3706 C CB  . LYS C 3 217 ? -82.668  -19.366 -69.485 1.00 176.99 ? 217 LYS H CB  1 
ATOM 3707 C CG  . LYS C 3 217 ? -81.677  -20.051 -70.413 1.00 170.54 ? 217 LYS H CG  1 
ATOM 3708 C CD  . LYS C 3 217 ? -82.037  -19.796 -71.870 1.00 170.60 ? 217 LYS H CD  1 
ATOM 3709 C CE  . LYS C 3 217 ? -81.138  -20.577 -72.815 1.00 153.82 ? 217 LYS H CE  1 
ATOM 3710 N NZ  . LYS C 3 217 ? -81.523  -20.369 -74.240 1.00 132.62 ? 217 LYS H NZ  1 
ATOM 3711 N N   . ARG C 3 218 ? -84.513  -22.067 -70.424 1.00 205.13 ? 218 ARG H N   1 
ATOM 3712 C CA  . ARG C 3 218 ? -84.551  -23.514 -70.268 1.00 197.79 ? 218 ARG H CA  1 
ATOM 3713 C C   . ARG C 3 218 ? -83.153  -24.084 -70.470 1.00 198.07 ? 218 ARG H C   1 
ATOM 3714 O O   . ARG C 3 218 ? -82.431  -23.677 -71.385 1.00 196.16 ? 218 ARG H O   1 
ATOM 3715 C CB  . ARG C 3 218 ? -85.523  -24.146 -71.267 1.00 191.47 ? 218 ARG H CB  1 
ATOM 3716 C CG  . ARG C 3 218 ? -85.339  -25.648 -71.444 1.00 181.62 ? 218 ARG H CG  1 
ATOM 3717 C CD  . ARG C 3 218 ? -85.760  -26.109 -72.832 1.00 179.80 ? 218 ARG H CD  1 
ATOM 3718 N NE  . ARG C 3 218 ? -87.178  -26.439 -72.902 1.00 175.85 ? 218 ARG H NE  1 
ATOM 3719 C CZ  . ARG C 3 218 ? -87.661  -27.674 -72.888 1.00 168.07 ? 218 ARG H CZ  1 
ATOM 3720 N NH1 . ARG C 3 218 ? -86.863  -28.726 -72.801 1.00 167.54 ? 218 ARG H NH1 1 
ATOM 3721 N NH2 . ARG C 3 218 ? -88.976  -27.858 -72.964 1.00 157.95 ? 218 ARG H NH2 1 
ATOM 3722 N N   . VAL C 3 219 ? -82.773  -25.023 -69.611 1.00 197.80 ? 219 VAL H N   1 
ATOM 3723 C CA  . VAL C 3 219 ? -81.462  -25.659 -69.677 1.00 193.48 ? 219 VAL H CA  1 
ATOM 3724 C C   . VAL C 3 219 ? -81.652  -27.072 -70.213 1.00 195.44 ? 219 VAL H C   1 
ATOM 3725 O O   . VAL C 3 219 ? -82.268  -27.921 -69.555 1.00 185.69 ? 219 VAL H O   1 
ATOM 3726 C CB  . VAL C 3 219 ? -80.761  -25.671 -68.313 1.00 186.24 ? 219 VAL H CB  1 
ATOM 3727 C CG1 . VAL C 3 219 ? -79.311  -26.106 -68.471 1.00 184.53 ? 219 VAL H CG1 1 
ATOM 3728 C CG2 . VAL C 3 219 ? -80.844  -24.299 -67.661 1.00 188.00 ? 219 VAL H CG2 1 
ATOM 3729 N N   . GLU C 3 220 ? -81.125  -27.324 -71.410 1.00 201.36 ? 220 GLU H N   1 
ATOM 3730 C CA  . GLU C 3 220 ? -81.123  -28.654 -72.012 1.00 186.88 ? 220 GLU H CA  1 
ATOM 3731 C C   . GLU C 3 220 ? -79.683  -28.995 -72.372 1.00 185.40 ? 220 GLU H C   1 
ATOM 3732 O O   . GLU C 3 220 ? -79.050  -28.251 -73.148 1.00 183.00 ? 220 GLU H O   1 
ATOM 3733 C CB  . GLU C 3 220 ? -82.027  -28.717 -73.246 1.00 174.30 ? 220 GLU H CB  1 
ATOM 3734 C CG  . GLU C 3 220 ? -83.429  -29.239 -72.968 1.00 174.04 ? 220 GLU H CG  1 
ATOM 3735 C CD  . GLU C 3 220 ? -84.063  -29.888 -74.186 1.00 173.95 ? 220 GLU H CD  1 
ATOM 3736 O OE1 . GLU C 3 220 ? -83.361  -30.060 -75.204 1.00 163.91 ? 220 GLU H OE1 1 
ATOM 3737 O OE2 . GLU C 3 220 ? -85.263  -30.230 -74.123 1.00 176.28 ? 220 GLU H OE2 1 
ATOM 3738 N N   . PRO C 3 221 ? -79.120  -30.093 -71.841 1.00 185.65 ? 221 PRO H N   1 
ATOM 3739 C CA  . PRO C 3 221 ? -77.725  -30.498 -72.063 1.00 177.01 ? 221 PRO H CA  1 
ATOM 3740 C C   . PRO C 3 221 ? -77.359  -30.630 -73.538 1.00 166.29 ? 221 PRO H C   1 
ATOM 3741 O O   . PRO C 3 221 ? -76.189  -30.444 -73.878 1.00 152.42 ? 221 PRO H O   1 
ATOM 3742 C CB  . PRO C 3 221 ? -77.644  -31.859 -71.366 1.00 173.65 ? 221 PRO H CB  1 
ATOM 3743 C CG  . PRO C 3 221 ? -78.710  -31.812 -70.329 1.00 170.80 ? 221 PRO H CG  1 
ATOM 3744 C CD  . PRO C 3 221 ? -79.825  -31.022 -70.942 1.00 175.62 ? 221 PRO H CD  1 
ATOM 3745 N N   . PHE D 4 1   ? -88.693  42.819  14.015  1.00 70.04  ? 137 PHE B N   1 
ATOM 3746 C CA  . PHE D 4 1   ? -88.294  41.861  12.992  1.00 106.92 ? 137 PHE B CA  1 
ATOM 3747 C C   . PHE D 4 1   ? -87.069  41.089  13.439  1.00 90.78  ? 137 PHE B C   1 
ATOM 3748 O O   . PHE D 4 1   ? -86.057  41.655  13.832  1.00 75.32  ? 137 PHE B O   1 
ATOM 3749 C CB  . PHE D 4 1   ? -88.029  42.558  11.658  1.00 112.99 ? 137 PHE B CB  1 
ATOM 3750 C CG  . PHE D 4 1   ? -89.243  43.226  11.071  1.00 109.45 ? 137 PHE B CG  1 
ATOM 3751 C CD1 . PHE D 4 1   ? -90.152  42.495  10.330  1.00 105.14 ? 137 PHE B CD1 1 
ATOM 3752 C CD2 . PHE D 4 1   ? -89.470  44.586  11.250  1.00 98.58  ? 137 PHE B CD2 1 
ATOM 3753 C CE1 . PHE D 4 1   ? -91.269  43.096  9.778   1.00 101.71 ? 137 PHE B CE1 1 
ATOM 3754 C CE2 . PHE D 4 1   ? -90.593  45.195  10.697  1.00 90.39  ? 137 PHE B CE2 1 
ATOM 3755 C CZ  . PHE D 4 1   ? -91.491  44.450  9.963   1.00 90.77  ? 137 PHE B CZ  1 
ATOM 3756 N N   . LEU D 4 2   ? -87.171  39.774  13.371  1.00 82.59  ? 138 LEU B N   1 
ATOM 3757 C CA  . LEU D 4 2   ? -86.151  38.900  13.918  1.00 82.66  ? 138 LEU B CA  1 
ATOM 3758 C C   . LEU D 4 2   ? -85.048  38.582  12.915  1.00 82.17  ? 138 LEU B C   1 
ATOM 3759 O O   . LEU D 4 2   ? -84.381  37.551  13.053  1.00 90.65  ? 138 LEU B O   1 
ATOM 3760 C CB  . LEU D 4 2   ? -86.814  37.622  14.420  1.00 74.65  ? 138 LEU B CB  1 
ATOM 3761 C CG  . LEU D 4 2   ? -87.549  37.742  15.762  1.00 77.40  ? 138 LEU B CG  1 
ATOM 3762 C CD1 . LEU D 4 2   ? -87.861  36.371  16.330  1.00 76.43  ? 138 LEU B CD1 1 
ATOM 3763 C CD2 . LEU D 4 2   ? -86.741  38.570  16.785  1.00 73.08  ? 138 LEU B CD2 1 
ATOM 3764 N N   . GLY D 4 3   ? -84.848  39.443  11.911  1.00 96.79  ? 139 GLY B N   1 
ATOM 3765 C CA  . GLY D 4 3   ? -83.867  39.205  10.863  1.00 86.96  ? 139 GLY B CA  1 
ATOM 3766 C C   . GLY D 4 3   ? -82.425  39.223  11.329  1.00 95.56  ? 139 GLY B C   1 
ATOM 3767 O O   . GLY D 4 3   ? -81.565  38.648  10.653  1.00 89.91  ? 139 GLY B O   1 
ATOM 3768 N N   . PHE D 4 4   ? -82.137  39.874  12.460  1.00 93.39  ? 140 PHE B N   1 
ATOM 3769 C CA  . PHE D 4 4   ? -80.769  39.905  12.969  1.00 86.60  ? 140 PHE B CA  1 
ATOM 3770 C C   . PHE D 4 4   ? -80.329  38.560  13.532  1.00 80.89  ? 140 PHE B C   1 
ATOM 3771 O O   . PHE D 4 4   ? -79.127  38.346  13.727  1.00 81.51  ? 140 PHE B O   1 
ATOM 3772 C CB  . PHE D 4 4   ? -80.619  40.995  14.036  1.00 77.56  ? 140 PHE B CB  1 
ATOM 3773 C CG  . PHE D 4 4   ? -81.584  40.866  15.182  1.00 89.28  ? 140 PHE B CG  1 
ATOM 3774 C CD1 . PHE D 4 4   ? -82.853  41.421  15.107  1.00 85.03  ? 140 PHE B CD1 1 
ATOM 3775 C CD2 . PHE D 4 4   ? -81.223  40.187  16.335  1.00 92.96  ? 140 PHE B CD2 1 
ATOM 3776 C CE1 . PHE D 4 4   ? -83.742  41.301  16.160  1.00 88.93  ? 140 PHE B CE1 1 
ATOM 3777 C CE2 . PHE D 4 4   ? -82.109  40.062  17.390  1.00 86.62  ? 140 PHE B CE2 1 
ATOM 3778 C CZ  . PHE D 4 4   ? -83.369  40.621  17.303  1.00 92.47  ? 140 PHE B CZ  1 
ATOM 3779 N N   . LEU D 4 5   ? -81.269  37.655  13.800  1.00 78.79  ? 141 LEU B N   1 
ATOM 3780 C CA  . LEU D 4 5   ? -80.951  36.314  14.270  1.00 74.01  ? 141 LEU B CA  1 
ATOM 3781 C C   . LEU D 4 5   ? -80.643  35.349  13.132  1.00 68.47  ? 141 LEU B C   1 
ATOM 3782 O O   . LEU D 4 5   ? -80.291  34.195  13.399  1.00 72.20  ? 141 LEU B O   1 
ATOM 3783 C CB  . LEU D 4 5   ? -82.110  35.763  15.106  1.00 64.61  ? 141 LEU B CB  1 
ATOM 3784 C CG  . LEU D 4 5   ? -82.506  36.565  16.345  1.00 68.79  ? 141 LEU B CG  1 
ATOM 3785 C CD1 . LEU D 4 5   ? -83.887  36.148  16.812  1.00 69.95  ? 141 LEU B CD1 1 
ATOM 3786 C CD2 . LEU D 4 5   ? -81.479  36.388  17.456  1.00 79.86  ? 141 LEU B CD2 1 
ATOM 3787 N N   . LEU D 4 6   ? -80.779  35.781  11.882  1.00 75.67  ? 142 LEU B N   1 
ATOM 3788 C CA  . LEU D 4 6   ? -80.506  34.905  10.755  1.00 71.67  ? 142 LEU B CA  1 
ATOM 3789 C C   . LEU D 4 6   ? -79.002  34.706  10.582  1.00 73.10  ? 142 LEU B C   1 
ATOM 3790 O O   . LEU D 4 6   ? -78.181  35.509  11.036  1.00 65.94  ? 142 LEU B O   1 
ATOM 3791 C CB  . LEU D 4 6   ? -81.116  35.476  9.475   1.00 51.12  ? 142 LEU B CB  1 
ATOM 3792 C CG  . LEU D 4 6   ? -82.639  35.381  9.338   1.00 60.21  ? 142 LEU B CG  1 
ATOM 3793 C CD1 . LEU D 4 6   ? -83.101  36.013  8.035   1.00 73.72  ? 142 LEU B CD1 1 
ATOM 3794 C CD2 . LEU D 4 6   ? -83.114  33.938  9.432   1.00 57.16  ? 142 LEU B CD2 1 
ATOM 3795 N N   . GLY D 4 7   ? -78.646  33.609  9.919   1.00 72.24  ? 143 GLY B N   1 
ATOM 3796 C CA  . GLY D 4 7   ? -77.262  33.301  9.637   1.00 56.15  ? 143 GLY B CA  1 
ATOM 3797 C C   . GLY D 4 7   ? -76.751  34.064  8.430   1.00 56.13  ? 143 GLY B C   1 
ATOM 3798 O O   . GLY D 4 7   ? -77.419  34.932  7.866   1.00 69.64  ? 143 GLY B O   1 
ATOM 3799 N N   . VAL D 4 8   ? -75.523  33.734  8.039   1.00 48.88  ? 144 VAL B N   1 
ATOM 3800 C CA  . VAL D 4 8   ? -74.869  34.350  6.891   1.00 44.94  ? 144 VAL B CA  1 
ATOM 3801 C C   . VAL D 4 8   ? -74.385  33.229  5.983   1.00 55.20  ? 144 VAL B C   1 
ATOM 3802 O O   . VAL D 4 8   ? -73.478  32.472  6.352   1.00 51.41  ? 144 VAL B O   1 
ATOM 3803 C CB  . VAL D 4 8   ? -73.704  35.261  7.303   1.00 43.40  ? 144 VAL B CB  1 
ATOM 3804 C CG1 . VAL D 4 8   ? -72.898  35.682  6.084   1.00 50.88  ? 144 VAL B CG1 1 
ATOM 3805 C CG2 . VAL D 4 8   ? -74.222  36.478  8.055   1.00 50.04  ? 144 VAL B CG2 1 
ATOM 3806 N N   . GLY D 4 9   ? -74.983  33.122  4.795   1.00 56.31  ? 145 GLY B N   1 
ATOM 3807 C CA  . GLY D 4 9   ? -74.578  32.146  3.810   1.00 47.34  ? 145 GLY B CA  1 
ATOM 3808 C C   . GLY D 4 9   ? -73.787  32.778  2.674   1.00 60.63  ? 145 GLY B C   1 
ATOM 3809 O O   . GLY D 4 9   ? -73.480  33.968  2.670   1.00 67.16  ? 145 GLY B O   1 
ATOM 3810 N N   . SER D 4 10  ? -73.447  31.941  1.697   1.00 58.22  ? 146 SER B N   1 
ATOM 3811 C CA  . SER D 4 10  ? -72.760  32.384  0.487   1.00 49.71  ? 146 SER B CA  1 
ATOM 3812 C C   . SER D 4 10  ? -73.595  31.934  -0.704  1.00 58.84  ? 146 SER B C   1 
ATOM 3813 O O   . SER D 4 10  ? -73.622  30.743  -1.035  1.00 70.40  ? 146 SER B O   1 
ATOM 3814 C CB  . SER D 4 10  ? -71.339  31.829  0.423   1.00 39.68  ? 146 SER B CB  1 
ATOM 3815 O OG  . SER D 4 10  ? -70.693  32.228  -0.769  1.00 59.48  ? 146 SER B OG  1 
ATOM 3816 N N   . ALA D 4 11  ? -74.265  32.891  -1.350  1.00 55.67  ? 147 ALA B N   1 
ATOM 3817 C CA  . ALA D 4 11  ? -75.322  32.557  -2.301  1.00 42.84  ? 147 ALA B CA  1 
ATOM 3818 C C   . ALA D 4 11  ? -74.787  31.771  -3.492  1.00 51.98  ? 147 ALA B C   1 
ATOM 3819 O O   . ALA D 4 11  ? -75.383  30.768  -3.900  1.00 65.96  ? 147 ALA B O   1 
ATOM 3820 C CB  . ALA D 4 11  ? -76.023  33.832  -2.768  1.00 49.78  ? 147 ALA B CB  1 
ATOM 3821 N N   . ILE D 4 12  ? -73.660  32.201  -4.058  1.00 57.29  ? 148 ILE B N   1 
ATOM 3822 C CA  . ILE D 4 12  ? -73.186  31.616  -5.309  1.00 58.05  ? 148 ILE B CA  1 
ATOM 3823 C C   . ILE D 4 12  ? -71.964  30.741  -5.061  1.00 53.01  ? 148 ILE B C   1 
ATOM 3824 O O   . ILE D 4 12  ? -71.147  30.525  -5.963  1.00 55.00  ? 148 ILE B O   1 
ATOM 3825 C CB  . ILE D 4 12  ? -72.879  32.709  -6.351  1.00 45.84  ? 148 ILE B CB  1 
ATOM 3826 C CG1 . ILE D 4 12  ? -71.695  33.569  -5.905  1.00 53.21  ? 148 ILE B CG1 1 
ATOM 3827 C CG2 . ILE D 4 12  ? -74.098  33.585  -6.565  1.00 40.38  ? 148 ILE B CG2 1 
ATOM 3828 C CD1 . ILE D 4 12  ? -71.316  34.633  -6.899  1.00 29.45  ? 148 ILE B CD1 1 
ATOM 3829 N N   . ALA D 4 13  ? -71.840  30.216  -3.840  1.00 59.97  ? 149 ALA B N   1 
ATOM 3830 C CA  . ALA D 4 13  ? -70.705  29.356  -3.520  1.00 65.57  ? 149 ALA B CA  1 
ATOM 3831 C C   . ALA D 4 13  ? -70.674  28.120  -4.413  1.00 52.67  ? 149 ALA B C   1 
ATOM 3832 O O   . ALA D 4 13  ? -69.612  27.738  -4.918  1.00 53.99  ? 149 ALA B O   1 
ATOM 3833 C CB  . ALA D 4 13  ? -70.751  28.955  -2.044  1.00 50.69  ? 149 ALA B CB  1 
ATOM 3834 N N   . SER D 4 14  ? -71.829  27.481  -4.622  1.00 43.57  ? 150 SER B N   1 
ATOM 3835 C CA  . SER D 4 14  ? -71.869  26.301  -5.482  1.00 53.04  ? 150 SER B CA  1 
ATOM 3836 C C   . SER D 4 14  ? -71.546  26.656  -6.929  1.00 61.39  ? 150 SER B C   1 
ATOM 3837 O O   . SER D 4 14  ? -70.794  25.938  -7.597  1.00 70.58  ? 150 SER B O   1 
ATOM 3838 C CB  . SER D 4 14  ? -73.236  25.623  -5.390  1.00 58.81  ? 150 SER B CB  1 
ATOM 3839 O OG  . SER D 4 14  ? -74.286  26.576  -5.389  1.00 63.92  ? 150 SER B OG  1 
ATOM 3840 N N   . GLY D 4 15  ? -72.105  27.760  -7.430  1.00 57.05  ? 151 GLY B N   1 
ATOM 3841 C CA  . GLY D 4 15  ? -71.813  28.172  -8.793  1.00 48.96  ? 151 GLY B CA  1 
ATOM 3842 C C   . GLY D 4 15  ? -70.357  28.542  -9.001  1.00 52.80  ? 151 GLY B C   1 
ATOM 3843 O O   . GLY D 4 15  ? -69.767  28.215  -10.035 1.00 51.28  ? 151 GLY B O   1 
ATOM 3844 N N   . VAL D 4 16  ? -69.758  29.234  -8.027  1.00 51.15  ? 152 VAL B N   1 
ATOM 3845 C CA  . VAL D 4 16  ? -68.350  29.606  -8.140  1.00 49.92  ? 152 VAL B CA  1 
ATOM 3846 C C   . VAL D 4 16  ? -67.474  28.360  -8.130  1.00 51.05  ? 152 VAL B C   1 
ATOM 3847 O O   . VAL D 4 16  ? -66.432  28.309  -8.796  1.00 61.49  ? 152 VAL B O   1 
ATOM 3848 C CB  . VAL D 4 16  ? -67.961  30.592  -7.022  1.00 44.58  ? 152 VAL B CB  1 
ATOM 3849 C CG1 . VAL D 4 16  ? -66.445  30.665  -6.861  1.00 49.56  ? 152 VAL B CG1 1 
ATOM 3850 C CG2 . VAL D 4 16  ? -68.536  31.970  -7.308  1.00 50.56  ? 152 VAL B CG2 1 
ATOM 3851 N N   . ALA D 4 17  ? -67.882  27.334  -7.380  1.00 53.68  ? 153 ALA B N   1 
ATOM 3852 C CA  . ALA D 4 17  ? -67.147  26.074  -7.395  1.00 63.47  ? 153 ALA B CA  1 
ATOM 3853 C C   . ALA D 4 17  ? -67.168  25.440  -8.782  1.00 54.75  ? 153 ALA B C   1 
ATOM 3854 O O   . ALA D 4 17  ? -66.158  24.888  -9.236  1.00 52.12  ? 153 ALA B O   1 
ATOM 3855 C CB  . ALA D 4 17  ? -67.725  25.117  -6.352  1.00 59.57  ? 153 ALA B CB  1 
ATOM 3856 N N   . VAL D 4 18  ? -68.307  25.510  -9.473  1.00 55.17  ? 154 VAL B N   1 
ATOM 3857 C CA  . VAL D 4 18  ? -68.385  24.959  -10.823 1.00 64.05  ? 154 VAL B CA  1 
ATOM 3858 C C   . VAL D 4 18  ? -67.537  25.784  -11.787 1.00 56.93  ? 154 VAL B C   1 
ATOM 3859 O O   . VAL D 4 18  ? -66.911  25.239  -12.705 1.00 46.77  ? 154 VAL B O   1 
ATOM 3860 C CB  . VAL D 4 18  ? -69.850  24.872  -11.286 1.00 61.14  ? 154 VAL B CB  1 
ATOM 3861 C CG1 . VAL D 4 18  ? -69.929  24.291  -12.697 1.00 55.29  ? 154 VAL B CG1 1 
ATOM 3862 C CG2 . VAL D 4 18  ? -70.666  24.043  -10.312 1.00 43.54  ? 154 VAL B CG2 1 
ATOM 3863 N N   . CYS D 4 19  ? -67.509  27.109  -11.603 1.00 48.83  ? 155 CYS B N   1 
ATOM 3864 C CA  . CYS D 4 19  ? -66.630  27.948  -12.411 1.00 57.75  ? 155 CYS B CA  1 
ATOM 3865 C C   . CYS D 4 19  ? -65.173  27.539  -12.236 1.00 63.46  ? 155 CYS B C   1 
ATOM 3866 O O   . CYS D 4 19  ? -64.433  27.408  -13.219 1.00 61.76  ? 155 CYS B O   1 
ATOM 3867 C CB  . CYS D 4 19  ? -66.806  29.422  -12.040 1.00 54.04  ? 155 CYS B CB  1 
ATOM 3868 S SG  . CYS D 4 19  ? -68.162  30.320  -12.845 1.00 95.56  ? 155 CYS B SG  1 
ATOM 3869 N N   . LYS D 4 20  ? -64.746  27.324  -10.991 1.00 64.75  ? 156 LYS B N   1 
ATOM 3870 C CA  . LYS D 4 20  ? -63.360  26.944  -10.742 1.00 68.10  ? 156 LYS B CA  1 
ATOM 3871 C C   . LYS D 4 20  ? -63.045  25.585  -11.357 1.00 66.51  ? 156 LYS B C   1 
ATOM 3872 O O   . LYS D 4 20  ? -61.952  25.381  -11.901 1.00 56.02  ? 156 LYS B O   1 
ATOM 3873 C CB  . LYS D 4 20  ? -63.082  26.950  -9.239  1.00 49.16  ? 156 LYS B CB  1 
ATOM 3874 C CG  . LYS D 4 20  ? -62.963  28.352  -8.656  1.00 64.73  ? 156 LYS B CG  1 
ATOM 3875 C CD  . LYS D 4 20  ? -62.501  28.333  -7.208  1.00 104.34 ? 156 LYS B CD  1 
ATOM 3876 C CE  . LYS D 4 20  ? -62.518  29.734  -6.610  1.00 100.37 ? 156 LYS B CE  1 
ATOM 3877 N NZ  . LYS D 4 20  ? -61.997  30.754  -7.566  1.00 100.26 ? 156 LYS B NZ  1 
ATOM 3878 N N   . VAL D 4 21  ? -63.995  24.647  -11.291 1.00 69.32  ? 157 VAL B N   1 
ATOM 3879 C CA  . VAL D 4 21  ? -63.807  23.341  -11.919 1.00 61.48  ? 157 VAL B CA  1 
ATOM 3880 C C   . VAL D 4 21  ? -63.656  23.497  -13.425 1.00 62.70  ? 157 VAL B C   1 
ATOM 3881 O O   . VAL D 4 21  ? -62.865  22.792  -14.064 1.00 65.67  ? 157 VAL B O   1 
ATOM 3882 C CB  . VAL D 4 21  ? -64.976  22.403  -11.562 1.00 63.04  ? 157 VAL B CB  1 
ATOM 3883 C CG1 . VAL D 4 21  ? -64.970  21.170  -12.456 1.00 62.99  ? 157 VAL B CG1 1 
ATOM 3884 C CG2 . VAL D 4 21  ? -64.912  22.004  -10.097 1.00 57.11  ? 157 VAL B CG2 1 
ATOM 3885 N N   . LEU D 4 22  ? -64.406  24.431  -14.014 1.00 69.01  ? 158 LEU B N   1 
ATOM 3886 C CA  . LEU D 4 22  ? -64.382  24.638  -15.457 1.00 61.55  ? 158 LEU B CA  1 
ATOM 3887 C C   . LEU D 4 22  ? -63.041  25.163  -15.952 1.00 60.15  ? 158 LEU B C   1 
ATOM 3888 O O   . LEU D 4 22  ? -62.755  25.059  -17.150 1.00 64.58  ? 158 LEU B O   1 
ATOM 3889 C CB  . LEU D 4 22  ? -65.492  25.610  -15.855 1.00 54.12  ? 158 LEU B CB  1 
ATOM 3890 C CG  . LEU D 4 22  ? -66.808  24.965  -16.277 1.00 49.26  ? 158 LEU B CG  1 
ATOM 3891 C CD1 . LEU D 4 22  ? -67.763  26.013  -16.824 1.00 54.45  ? 158 LEU B CD1 1 
ATOM 3892 C CD2 . LEU D 4 22  ? -66.545  23.872  -17.297 1.00 82.54  ? 158 LEU B CD2 1 
ATOM 3893 N N   . HIS D 4 23  ? -62.222  25.734  -15.069 1.00 61.17  ? 159 HIS B N   1 
ATOM 3894 C CA  . HIS D 4 23  ? -60.919  26.255  -15.458 1.00 59.04  ? 159 HIS B CA  1 
ATOM 3895 C C   . HIS D 4 23  ? -59.839  25.184  -15.511 1.00 70.22  ? 159 HIS B C   1 
ATOM 3896 O O   . HIS D 4 23  ? -58.724  25.476  -15.955 1.00 78.45  ? 159 HIS B O   1 
ATOM 3897 C CB  . HIS D 4 23  ? -60.490  27.365  -14.497 1.00 66.03  ? 159 HIS B CB  1 
ATOM 3898 C CG  . HIS D 4 23  ? -61.115  28.692  -14.789 1.00 54.86  ? 159 HIS B CG  1 
ATOM 3899 N ND1 . HIS D 4 23  ? -62.413  28.995  -14.440 1.00 63.12  ? 159 HIS B ND1 1 
ATOM 3900 C CD2 . HIS D 4 23  ? -60.618  29.799  -15.388 1.00 58.67  ? 159 HIS B CD2 1 
ATOM 3901 C CE1 . HIS D 4 23  ? -62.691  30.230  -14.818 1.00 70.60  ? 159 HIS B CE1 1 
ATOM 3902 N NE2 . HIS D 4 23  ? -61.619  30.740  -15.395 1.00 66.19  ? 159 HIS B NE2 1 
ATOM 3903 N N   . LEU D 4 24  ? -60.139  23.964  -15.077 1.00 65.54  ? 160 LEU B N   1 
ATOM 3904 C CA  . LEU D 4 24  ? -59.156  22.895  -15.109 1.00 54.29  ? 160 LEU B CA  1 
ATOM 3905 C C   . LEU D 4 24  ? -58.846  22.509  -16.555 1.00 78.51  ? 160 LEU B C   1 
ATOM 3906 O O   . LEU D 4 24  ? -59.599  22.813  -17.485 1.00 77.55  ? 160 LEU B O   1 
ATOM 3907 C CB  . LEU D 4 24  ? -59.664  21.684  -14.326 1.00 70.75  ? 160 LEU B CB  1 
ATOM 3908 C CG  . LEU D 4 24  ? -59.894  21.896  -12.822 1.00 68.67  ? 160 LEU B CG  1 
ATOM 3909 C CD1 . LEU D 4 24  ? -60.207  20.575  -12.136 1.00 75.04  ? 160 LEU B CD1 1 
ATOM 3910 C CD2 . LEU D 4 24  ? -58.712  22.589  -12.154 1.00 50.16  ? 160 LEU B CD2 1 
ATOM 3911 N N   . GLU D 4 25  ? -57.709  21.841  -16.738 1.00 83.48  ? 161 GLU B N   1 
ATOM 3912 C CA  . GLU D 4 25  ? -57.252  21.494  -18.077 1.00 74.82  ? 161 GLU B CA  1 
ATOM 3913 C C   . GLU D 4 25  ? -58.189  20.480  -18.725 1.00 79.96  ? 161 GLU B C   1 
ATOM 3914 O O   . GLU D 4 25  ? -58.512  19.447  -18.131 1.00 78.96  ? 161 GLU B O   1 
ATOM 3915 C CB  . GLU D 4 25  ? -55.828  20.940  -18.022 1.00 75.62  ? 161 GLU B CB  1 
ATOM 3916 C CG  . GLU D 4 25  ? -55.282  20.473  -19.369 1.00 95.66  ? 161 GLU B CG  1 
ATOM 3917 C CD  . GLU D 4 25  ? -55.006  21.610  -20.344 1.00 102.32 ? 161 GLU B CD  1 
ATOM 3918 O OE1 . GLU D 4 25  ? -55.162  22.792  -19.967 1.00 106.26 ? 161 GLU B OE1 1 
ATOM 3919 O OE2 . GLU D 4 25  ? -54.639  21.315  -21.500 1.00 100.83 ? 161 GLU B OE2 1 
ATOM 3920 N N   . GLY D 4 26  ? -58.623  20.780  -19.950 1.00 79.56  ? 162 GLY B N   1 
ATOM 3921 C CA  . GLY D 4 26  ? -59.465  19.889  -20.716 1.00 70.04  ? 162 GLY B CA  1 
ATOM 3922 C C   . GLY D 4 26  ? -60.949  19.993  -20.435 1.00 73.06  ? 162 GLY B C   1 
ATOM 3923 O O   . GLY D 4 26  ? -61.741  19.357  -21.143 1.00 75.42  ? 162 GLY B O   1 
ATOM 3924 N N   . GLU D 4 27  ? -61.356  20.774  -19.431 1.00 75.21  ? 163 GLU B N   1 
ATOM 3925 C CA  . GLU D 4 27  ? -62.776  20.887  -19.111 1.00 68.75  ? 163 GLU B CA  1 
ATOM 3926 C C   . GLU D 4 27  ? -63.539  21.630  -20.198 1.00 69.31  ? 163 GLU B C   1 
ATOM 3927 O O   . GLU D 4 27  ? -64.634  21.212  -20.591 1.00 75.43  ? 163 GLU B O   1 
ATOM 3928 C CB  . GLU D 4 27  ? -62.958  21.578  -17.760 1.00 72.66  ? 163 GLU B CB  1 
ATOM 3929 C CG  . GLU D 4 27  ? -62.487  20.743  -16.590 1.00 77.31  ? 163 GLU B CG  1 
ATOM 3930 C CD  . GLU D 4 27  ? -63.215  19.416  -16.507 1.00 93.26  ? 163 GLU B CD  1 
ATOM 3931 O OE1 . GLU D 4 27  ? -64.406  19.411  -16.131 1.00 91.13  ? 163 GLU B OE1 1 
ATOM 3932 O OE2 . GLU D 4 27  ? -62.597  18.379  -16.830 1.00 103.59 ? 163 GLU B OE2 1 
ATOM 3933 N N   . VAL D 4 28  ? -62.985  22.740  -20.688 1.00 71.54  ? 164 VAL B N   1 
ATOM 3934 C CA  . VAL D 4 28  ? -63.653  23.489  -21.747 1.00 68.56  ? 164 VAL B CA  1 
ATOM 3935 C C   . VAL D 4 28  ? -63.665  22.686  -23.041 1.00 63.63  ? 164 VAL B C   1 
ATOM 3936 O O   . VAL D 4 28  ? -64.646  22.710  -23.793 1.00 69.93  ? 164 VAL B O   1 
ATOM 3937 C CB  . VAL D 4 28  ? -62.988  24.864  -21.928 1.00 57.98  ? 164 VAL B CB  1 
ATOM 3938 C CG1 . VAL D 4 28  ? -63.792  25.718  -22.887 1.00 55.70  ? 164 VAL B CG1 1 
ATOM 3939 C CG2 . VAL D 4 28  ? -62.865  25.557  -20.582 1.00 62.41  ? 164 VAL B CG2 1 
ATOM 3940 N N   . ASN D 4 29  ? -62.581  21.955  -23.319 1.00 71.35  ? 165 ASN B N   1 
ATOM 3941 C CA  . ASN D 4 29  ? -62.544  21.114  -24.511 1.00 70.92  ? 165 ASN B CA  1 
ATOM 3942 C C   . ASN D 4 29  ? -63.582  20.002  -24.431 1.00 69.28  ? 165 ASN B C   1 
ATOM 3943 O O   . ASN D 4 29  ? -64.193  19.637  -25.442 1.00 62.13  ? 165 ASN B O   1 
ATOM 3944 C CB  . ASN D 4 29  ? -61.143  20.533  -24.698 1.00 81.52  ? 165 ASN B CB  1 
ATOM 3945 C CG  . ASN D 4 29  ? -60.119  21.591  -25.056 1.00 109.05 ? 165 ASN B CG  1 
ATOM 3946 O OD1 . ASN D 4 29  ? -59.569  22.262  -24.178 1.00 125.80 ? 165 ASN B OD1 1 
ATOM 3947 N ND2 . ASN D 4 29  ? -59.859  21.749  -26.349 1.00 89.40  ? 165 ASN B ND2 1 
ATOM 3948 N N   . LYS D 4 30  ? -63.790  19.448  -23.234 1.00 69.32  ? 166 LYS B N   1 
ATOM 3949 C CA  . LYS D 4 30  ? -64.826  18.436  -23.054 1.00 57.68  ? 166 LYS B CA  1 
ATOM 3950 C C   . LYS D 4 30  ? -66.205  18.999  -23.373 1.00 64.24  ? 166 LYS B C   1 
ATOM 3951 O O   . LYS D 4 30  ? -67.007  18.351  -24.058 1.00 68.21  ? 166 LYS B O   1 
ATOM 3952 C CB  . LYS D 4 30  ? -64.784  17.899  -21.623 1.00 59.80  ? 166 LYS B CB  1 
ATOM 3953 C CG  . LYS D 4 30  ? -65.462  16.555  -21.436 1.00 75.55  ? 166 LYS B CG  1 
ATOM 3954 C CD  . LYS D 4 30  ? -65.511  16.165  -19.969 1.00 64.58  ? 166 LYS B CD  1 
ATOM 3955 C CE  . LYS D 4 30  ? -64.120  16.113  -19.360 1.00 68.18  ? 166 LYS B CE  1 
ATOM 3956 N NZ  . LYS D 4 30  ? -64.171  15.827  -17.898 1.00 72.46  ? 166 LYS B NZ  1 
ATOM 3957 N N   . ILE D 4 31  ? -66.497  20.207  -22.886 1.00 64.51  ? 167 ILE B N   1 
ATOM 3958 C CA  . ILE D 4 31  ? -67.783  20.842  -23.160 1.00 67.58  ? 167 ILE B CA  1 
ATOM 3959 C C   . ILE D 4 31  ? -67.925  21.163  -24.643 1.00 54.35  ? 167 ILE B C   1 
ATOM 3960 O O   . ILE D 4 31  ? -68.990  20.958  -25.237 1.00 47.98  ? 167 ILE B O   1 
ATOM 3961 C CB  . ILE D 4 31  ? -67.949  22.102  -22.293 1.00 57.60  ? 167 ILE B CB  1 
ATOM 3962 C CG1 . ILE D 4 31  ? -68.002  21.725  -20.811 1.00 63.90  ? 167 ILE B CG1 1 
ATOM 3963 C CG2 . ILE D 4 31  ? -69.179  22.892  -22.724 1.00 51.11  ? 167 ILE B CG2 1 
ATOM 3964 C CD1 . ILE D 4 31  ? -68.728  22.732  -19.947 1.00 66.39  ? 167 ILE B CD1 1 
ATOM 3965 N N   . LYS D 4 32  ? -66.863  21.683  -25.261 1.00 54.93  ? 168 LYS B N   1 
ATOM 3966 C CA  . LYS D 4 32  ? -66.942  22.044  -26.673 1.00 58.51  ? 168 LYS B CA  1 
ATOM 3967 C C   . LYS D 4 32  ? -67.207  20.820  -27.540 1.00 54.47  ? 168 LYS B C   1 
ATOM 3968 O O   . LYS D 4 32  ? -68.043  20.864  -28.449 1.00 51.90  ? 168 LYS B O   1 
ATOM 3969 C CB  . LYS D 4 32  ? -65.658  22.753  -27.104 1.00 44.97  ? 168 LYS B CB  1 
ATOM 3970 C CG  . LYS D 4 32  ? -65.804  23.561  -28.379 1.00 65.19  ? 168 LYS B CG  1 
ATOM 3971 C CD  . LYS D 4 32  ? -64.667  24.564  -28.529 1.00 74.03  ? 168 LYS B CD  1 
ATOM 3972 C CE  . LYS D 4 32  ? -63.315  23.874  -28.557 1.00 72.51  ? 168 LYS B CE  1 
ATOM 3973 N NZ  . LYS D 4 32  ? -62.216  24.835  -28.835 1.00 72.67  ? 168 LYS B NZ  1 
ATOM 3974 N N   . SER D 4 33  ? -66.520  19.709  -27.259 1.00 63.94  ? 169 SER B N   1 
ATOM 3975 C CA  . SER D 4 33  ? -66.743  18.488  -28.026 1.00 60.20  ? 169 SER B CA  1 
ATOM 3976 C C   . SER D 4 33  ? -68.136  17.919  -27.771 1.00 58.26  ? 169 SER B C   1 
ATOM 3977 O O   . SER D 4 33  ? -68.778  17.398  -28.689 1.00 58.02  ? 169 SER B O   1 
ATOM 3978 C CB  . SER D 4 33  ? -65.664  17.457  -27.693 1.00 57.74  ? 169 SER B CB  1 
ATOM 3979 O OG  . SER D 4 33  ? -66.039  16.161  -28.127 1.00 58.23  ? 169 SER B OG  1 
ATOM 3980 N N   . ALA D 4 34  ? -68.617  18.006  -26.529 1.00 68.90  ? 170 ALA B N   1 
ATOM 3981 C CA  . ALA D 4 34  ? -69.945  17.489  -26.209 1.00 65.82  ? 170 ALA B CA  1 
ATOM 3982 C C   . ALA D 4 34  ? -71.034  18.269  -26.935 1.00 58.34  ? 170 ALA B C   1 
ATOM 3983 O O   . ALA D 4 34  ? -72.033  17.690  -27.377 1.00 71.04  ? 170 ALA B O   1 
ATOM 3984 C CB  . ALA D 4 34  ? -70.174  17.527  -24.699 1.00 61.31  ? 170 ALA B CB  1 
ATOM 3985 N N   . LEU D 4 35  ? -70.869  19.582  -27.052 1.00 60.22  ? 171 LEU B N   1 
ATOM 3986 C CA  . LEU D 4 35  ? -71.830  20.431  -27.757 1.00 63.46  ? 171 LEU B CA  1 
ATOM 3987 C C   . LEU D 4 35  ? -71.441  20.628  -29.220 1.00 65.96  ? 171 LEU B C   1 
ATOM 3988 O O   . LEU D 4 35  ? -71.350  21.751  -29.712 1.00 77.49  ? 171 LEU B O   1 
ATOM 3989 C CB  . LEU D 4 35  ? -71.953  21.769  -27.041 1.00 59.96  ? 171 LEU B CB  1 
ATOM 3990 C CG  . LEU D 4 35  ? -72.733  21.772  -25.728 1.00 44.03  ? 171 LEU B CG  1 
ATOM 3991 C CD1 . LEU D 4 35  ? -72.728  23.160  -25.123 1.00 50.11  ? 171 LEU B CD1 1 
ATOM 3992 C CD2 . LEU D 4 35  ? -74.157  21.289  -25.956 1.00 52.26  ? 171 LEU B CD2 1 
ATOM 3993 N N   . LEU D 4 36  ? -71.205  19.526  -29.931 1.00 62.83  ? 172 LEU B N   1 
ATOM 3994 C CA  . LEU D 4 36  ? -70.834  19.564  -31.342 1.00 54.92  ? 172 LEU B CA  1 
ATOM 3995 C C   . LEU D 4 36  ? -72.019  19.299  -32.261 1.00 60.27  ? 172 LEU B C   1 
ATOM 3996 O O   . LEU D 4 36  ? -72.206  20.005  -33.257 1.00 63.05  ? 172 LEU B O   1 
ATOM 3997 C CB  . LEU D 4 36  ? -69.722  18.547  -31.626 1.00 51.01  ? 172 LEU B CB  1 
ATOM 3998 C CG  . LEU D 4 36  ? -69.376  18.326  -33.103 1.00 63.32  ? 172 LEU B CG  1 
ATOM 3999 C CD1 . LEU D 4 36  ? -68.391  19.375  -33.601 1.00 66.96  ? 172 LEU B CD1 1 
ATOM 4000 C CD2 . LEU D 4 36  ? -68.832  16.923  -33.339 1.00 61.51  ? 172 LEU B CD2 1 
ATOM 4001 N N   . SER D 4 37  ? -72.823  18.287  -31.944 1.00 55.11  ? 173 SER B N   1 
ATOM 4002 C CA  . SER D 4 37  ? -73.971  17.904  -32.750 1.00 45.21  ? 173 SER B CA  1 
ATOM 4003 C C   . SER D 4 37  ? -75.300  18.279  -32.111 1.00 51.28  ? 173 SER B C   1 
ATOM 4004 O O   . SER D 4 37  ? -76.354  17.950  -32.665 1.00 58.49  ? 173 SER B O   1 
ATOM 4005 C CB  . SER D 4 37  ? -73.939  16.397  -33.014 1.00 51.42  ? 173 SER B CB  1 
ATOM 4006 O OG  . SER D 4 37  ? -72.652  15.984  -33.438 1.00 65.05  ? 173 SER B OG  1 
ATOM 4007 N N   . THR D 4 38  ? -75.283  18.951  -30.962 1.00 58.30  ? 174 THR B N   1 
ATOM 4008 C CA  . THR D 4 38  ? -76.509  19.289  -30.256 1.00 54.29  ? 174 THR B CA  1 
ATOM 4009 C C   . THR D 4 38  ? -76.289  20.568  -29.463 1.00 50.15  ? 174 THR B C   1 
ATOM 4010 O O   . THR D 4 38  ? -75.154  20.970  -29.194 1.00 57.54  ? 174 THR B O   1 
ATOM 4011 C CB  . THR D 4 38  ? -76.958  18.156  -29.321 1.00 53.52  ? 174 THR B CB  1 
ATOM 4012 O OG1 . THR D 4 38  ? -78.144  18.552  -28.621 1.00 43.98  ? 174 THR B OG1 1 
ATOM 4013 C CG2 . THR D 4 38  ? -75.866  17.825  -28.313 1.00 45.20  ? 174 THR B CG2 1 
ATOM 4014 N N   . ASN D 4 39  ? -77.395  21.210  -29.099 1.00 39.89  ? 175 ASN B N   1 
ATOM 4015 C CA  . ASN D 4 39  ? -77.347  22.391  -28.250 1.00 52.05  ? 175 ASN B CA  1 
ATOM 4016 C C   . ASN D 4 39  ? -77.467  22.063  -26.766 1.00 60.34  ? 175 ASN B C   1 
ATOM 4017 O O   . ASN D 4 39  ? -77.375  22.974  -25.938 1.00 55.22  ? 175 ASN B O   1 
ATOM 4018 C CB  . ASN D 4 39  ? -78.456  23.372  -28.637 1.00 46.46  ? 175 ASN B CB  1 
ATOM 4019 C CG  . ASN D 4 39  ? -79.838  22.841  -28.313 1.00 55.72  ? 175 ASN B CG  1 
ATOM 4020 O OD1 . ASN D 4 39  ? -80.069  21.633  -28.338 1.00 56.40  ? 175 ASN B OD1 1 
ATOM 4021 N ND2 . ASN D 4 39  ? -80.751  23.739  -27.958 1.00 47.58  ? 175 ASN B ND2 1 
ATOM 4022 N N   . LYS D 4 40  ? -77.659  20.796  -26.408 1.00 52.86  ? 176 LYS B N   1 
ATOM 4023 C CA  . LYS D 4 40  ? -77.939  20.432  -25.025 1.00 43.74  ? 176 LYS B CA  1 
ATOM 4024 C C   . LYS D 4 40  ? -77.404  19.032  -24.762 1.00 44.63  ? 176 LYS B C   1 
ATOM 4025 O O   . LYS D 4 40  ? -77.824  18.078  -25.422 1.00 55.91  ? 176 LYS B O   1 
ATOM 4026 C CB  . LYS D 4 40  ? -79.444  20.505  -24.752 1.00 45.58  ? 176 LYS B CB  1 
ATOM 4027 C CG  . LYS D 4 40  ? -79.879  19.883  -23.440 1.00 68.49  ? 176 LYS B CG  1 
ATOM 4028 C CD  . LYS D 4 40  ? -81.382  19.999  -23.245 1.00 45.42  ? 176 LYS B CD  1 
ATOM 4029 C CE  . LYS D 4 40  ? -82.139  19.193  -24.283 1.00 70.69  ? 176 LYS B CE  1 
ATOM 4030 N NZ  . LYS D 4 40  ? -83.609  19.371  -24.131 1.00 75.20  ? 176 LYS B NZ  1 
ATOM 4031 N N   . ALA D 4 41  ? -76.488  18.908  -23.801 1.00 55.65  ? 177 ALA B N   1 
ATOM 4032 C CA  . ALA D 4 41  ? -75.899  17.619  -23.465 1.00 51.95  ? 177 ALA B CA  1 
ATOM 4033 C C   . ALA D 4 41  ? -75.491  17.612  -21.997 1.00 58.00  ? 177 ALA B C   1 
ATOM 4034 O O   . ALA D 4 41  ? -75.327  18.664  -21.373 1.00 58.79  ? 177 ALA B O   1 
ATOM 4035 C CB  . ALA D 4 41  ? -74.691  17.304  -24.356 1.00 54.39  ? 177 ALA B CB  1 
ATOM 4036 N N   . VAL D 4 42  ? -75.329  16.407  -21.450 1.00 55.65  ? 178 VAL B N   1 
ATOM 4037 C CA  . VAL D 4 42  ? -74.907  16.216  -20.065 1.00 52.07  ? 178 VAL B CA  1 
ATOM 4038 C C   . VAL D 4 42  ? -73.424  15.880  -20.047 1.00 47.38  ? 178 VAL B C   1 
ATOM 4039 O O   . VAL D 4 42  ? -72.979  14.950  -20.732 1.00 55.55  ? 178 VAL B O   1 
ATOM 4040 C CB  . VAL D 4 42  ? -75.724  15.114  -19.370 1.00 40.55  ? 178 VAL B CB  1 
ATOM 4041 C CG1 . VAL D 4 42  ? -75.449  15.132  -17.877 1.00 51.46  ? 178 VAL B CG1 1 
ATOM 4042 C CG2 . VAL D 4 42  ? -77.208  15.301  -19.634 1.00 44.01  ? 178 VAL B CG2 1 
ATOM 4043 N N   . VAL D 4 43  ? -72.661  16.626  -19.255 1.00 45.93  ? 179 VAL B N   1 
ATOM 4044 C CA  . VAL D 4 43  ? -71.210  16.505  -19.206 1.00 51.29  ? 179 VAL B CA  1 
ATOM 4045 C C   . VAL D 4 43  ? -70.794  16.188  -17.775 1.00 60.08  ? 179 VAL B C   1 
ATOM 4046 O O   . VAL D 4 43  ? -71.270  16.823  -16.826 1.00 57.01  ? 179 VAL B O   1 
ATOM 4047 C CB  . VAL D 4 43  ? -70.523  17.788  -19.709 1.00 46.65  ? 179 VAL B CB  1 
ATOM 4048 C CG1 . VAL D 4 43  ? -69.018  17.710  -19.507 1.00 52.44  ? 179 VAL B CG1 1 
ATOM 4049 C CG2 . VAL D 4 43  ? -70.857  18.016  -21.170 1.00 59.62  ? 179 VAL B CG2 1 
ATOM 4050 N N   . SER D 4 44  ? -69.921  15.197  -17.623 1.00 60.38  ? 180 SER B N   1 
ATOM 4051 C CA  . SER D 4 44  ? -69.335  14.850  -16.336 1.00 59.07  ? 180 SER B CA  1 
ATOM 4052 C C   . SER D 4 44  ? -67.987  15.549  -16.216 1.00 67.81  ? 180 SER B C   1 
ATOM 4053 O O   . SER D 4 44  ? -67.088  15.317  -17.032 1.00 69.50  ? 180 SER B O   1 
ATOM 4054 C CB  . SER D 4 44  ? -69.176  13.336  -16.195 1.00 67.61  ? 180 SER B CB  1 
ATOM 4055 O OG  . SER D 4 44  ? -70.389  12.731  -15.781 1.00 86.06  ? 180 SER B OG  1 
ATOM 4056 N N   . LEU D 4 45  ? -67.852  16.405  -15.207 1.00 69.57  ? 181 LEU B N   1 
ATOM 4057 C CA  . LEU D 4 45  ? -66.631  17.170  -15.016 1.00 68.95  ? 181 LEU B CA  1 
ATOM 4058 C C   . LEU D 4 45  ? -65.579  16.316  -14.307 1.00 76.88  ? 181 LEU B C   1 
ATOM 4059 O O   . LEU D 4 45  ? -65.824  15.168  -13.923 1.00 76.47  ? 181 LEU B O   1 
ATOM 4060 C CB  . LEU D 4 45  ? -66.933  18.451  -14.242 1.00 64.07  ? 181 LEU B CB  1 
ATOM 4061 C CG  . LEU D 4 45  ? -68.059  19.311  -14.826 1.00 50.43  ? 181 LEU B CG  1 
ATOM 4062 C CD1 . LEU D 4 45  ? -68.422  20.453  -13.889 1.00 66.63  ? 181 LEU B CD1 1 
ATOM 4063 C CD2 . LEU D 4 45  ? -67.678  19.840  -16.196 1.00 61.52  ? 181 LEU B CD2 1 
ATOM 4064 N N   . SER D 4 46  ? -64.384  16.889  -14.130 1.00 72.88  ? 182 SER B N   1 
ATOM 4065 C CA  . SER D 4 46  ? -63.276  16.156  -13.524 1.00 65.81  ? 182 SER B CA  1 
ATOM 4066 C C   . SER D 4 46  ? -63.526  15.806  -12.064 1.00 63.05  ? 182 SER B C   1 
ATOM 4067 O O   . SER D 4 46  ? -62.889  14.883  -11.547 1.00 72.12  ? 182 SER B O   1 
ATOM 4068 C CB  . SER D 4 46  ? -61.982  16.962  -13.635 1.00 66.15  ? 182 SER B CB  1 
ATOM 4069 O OG  . SER D 4 46  ? -61.723  17.335  -14.976 1.00 98.42  ? 182 SER B OG  1 
ATOM 4070 N N   . ASN D 4 47  ? -64.423  16.518  -11.389 1.00 68.29  ? 183 ASN B N   1 
ATOM 4071 C CA  . ASN D 4 47  ? -64.715  16.266  -9.986  1.00 68.52  ? 183 ASN B CA  1 
ATOM 4072 C C   . ASN D 4 47  ? -65.888  15.311  -9.787  1.00 71.76  ? 183 ASN B C   1 
ATOM 4073 O O   . ASN D 4 47  ? -66.334  15.125  -8.650  1.00 77.91  ? 183 ASN B O   1 
ATOM 4074 C CB  . ASN D 4 47  ? -64.961  17.592  -9.255  1.00 70.54  ? 183 ASN B CB  1 
ATOM 4075 C CG  . ASN D 4 47  ? -66.297  18.217  -9.600  1.00 73.75  ? 183 ASN B CG  1 
ATOM 4076 O OD1 . ASN D 4 47  ? -66.867  17.959  -10.661 1.00 70.52  ? 183 ASN B OD1 1 
ATOM 4077 N ND2 . ASN D 4 47  ? -66.801  19.059  -8.703  1.00 89.87  ? 183 ASN B ND2 1 
ATOM 4078 N N   . GLY D 4 48  ? -66.388  14.700  -10.858 1.00 65.35  ? 184 GLY B N   1 
ATOM 4079 C CA  . GLY D 4 48  ? -67.426  13.695  -10.755 1.00 64.43  ? 184 GLY B CA  1 
ATOM 4080 C C   . GLY D 4 48  ? -68.847  14.207  -10.798 1.00 69.28  ? 184 GLY B C   1 
ATOM 4081 O O   . GLY D 4 48  ? -69.777  13.411  -10.621 1.00 78.64  ? 184 GLY B O   1 
ATOM 4082 N N   . VAL D 4 49  ? -69.051  15.500  -11.031 1.00 72.95  ? 185 VAL B N   1 
ATOM 4083 C CA  . VAL D 4 49  ? -70.382  16.096  -11.074 1.00 69.65  ? 185 VAL B CA  1 
ATOM 4084 C C   . VAL D 4 49  ? -70.849  16.169  -12.521 1.00 72.09  ? 185 VAL B C   1 
ATOM 4085 O O   . VAL D 4 49  ? -70.102  16.609  -13.406 1.00 62.79  ? 185 VAL B O   1 
ATOM 4086 C CB  . VAL D 4 49  ? -70.392  17.490  -10.425 1.00 59.67  ? 185 VAL B CB  1 
ATOM 4087 C CG1 . VAL D 4 49  ? -71.814  18.027  -10.353 1.00 68.05  ? 185 VAL B CG1 1 
ATOM 4088 C CG2 . VAL D 4 49  ? -69.766  17.434  -9.044  1.00 66.23  ? 185 VAL B CG2 1 
ATOM 4089 N N   . SER D 4 50  ? -72.084  15.738  -12.761 1.00 71.42  ? 186 SER B N   1 
ATOM 4090 C CA  . SER D 4 50  ? -72.705  15.790  -14.078 1.00 49.53  ? 186 SER B CA  1 
ATOM 4091 C C   . SER D 4 50  ? -73.586  17.030  -14.156 1.00 53.79  ? 186 SER B C   1 
ATOM 4092 O O   . SER D 4 50  ? -74.518  17.183  -13.360 1.00 55.98  ? 186 SER B O   1 
ATOM 4093 C CB  . SER D 4 50  ? -73.532  14.531  -14.335 1.00 41.58  ? 186 SER B CB  1 
ATOM 4094 O OG  . SER D 4 50  ? -72.763  13.367  -14.095 1.00 76.47  ? 186 SER B OG  1 
ATOM 4095 N N   . VAL D 4 51  ? -73.305  17.901  -15.119 1.00 50.41  ? 187 VAL B N   1 
ATOM 4096 C CA  . VAL D 4 51  ? -74.011  19.168  -15.253 1.00 57.88  ? 187 VAL B CA  1 
ATOM 4097 C C   . VAL D 4 51  ? -74.580  19.274  -16.660 1.00 47.67  ? 187 VAL B C   1 
ATOM 4098 O O   . VAL D 4 51  ? -73.921  18.902  -17.637 1.00 56.49  ? 187 VAL B O   1 
ATOM 4099 C CB  . VAL D 4 51  ? -73.091  20.367  -14.943 1.00 54.75  ? 187 VAL B CB  1 
ATOM 4100 C CG1 . VAL D 4 51  ? -72.912  20.512  -13.439 1.00 70.33  ? 187 VAL B CG1 1 
ATOM 4101 C CG2 . VAL D 4 51  ? -71.744  20.195  -15.626 1.00 46.31  ? 187 VAL B CG2 1 
ATOM 4102 N N   . LEU D 4 52  ? -75.816  19.758  -16.757 1.00 49.08  ? 188 LEU B N   1 
ATOM 4103 C CA  . LEU D 4 52  ? -76.407  20.037  -18.059 1.00 49.49  ? 188 LEU B CA  1 
ATOM 4104 C C   . LEU D 4 52  ? -75.698  21.215  -18.713 1.00 49.73  ? 188 LEU B C   1 
ATOM 4105 O O   . LEU D 4 52  ? -75.321  22.184  -18.047 1.00 54.79  ? 188 LEU B O   1 
ATOM 4106 C CB  . LEU D 4 52  ? -77.898  20.336  -17.920 1.00 38.70  ? 188 LEU B CB  1 
ATOM 4107 C CG  . LEU D 4 52  ? -78.840  19.157  -18.150 1.00 53.94  ? 188 LEU B CG  1 
ATOM 4108 C CD1 . LEU D 4 52  ? -80.211  19.442  -17.556 1.00 56.00  ? 188 LEU B CD1 1 
ATOM 4109 C CD2 . LEU D 4 52  ? -78.944  18.856  -19.636 1.00 72.44  ? 188 LEU B CD2 1 
ATOM 4110 N N   . THR D 4 53  ? -75.516  21.131  -20.027 1.00 51.20  ? 189 THR B N   1 
ATOM 4111 C CA  . THR D 4 53  ? -74.801  22.159  -20.768 1.00 48.30  ? 189 THR B CA  1 
ATOM 4112 C C   . THR D 4 53  ? -75.629  22.581  -21.972 1.00 49.57  ? 189 THR B C   1 
ATOM 4113 O O   . THR D 4 53  ? -76.147  21.732  -22.703 1.00 52.59  ? 189 THR B O   1 
ATOM 4114 C CB  . THR D 4 53  ? -73.426  21.666  -21.220 1.00 38.82  ? 189 THR B CB  1 
ATOM 4115 O OG1 . THR D 4 53  ? -72.788  20.981  -20.137 1.00 58.99  ? 189 THR B OG1 1 
ATOM 4116 C CG2 . THR D 4 53  ? -72.562  22.843  -21.605 1.00 52.69  ? 189 THR B CG2 1 
ATOM 4117 N N   . PHE D 4 54  ? -75.747  23.890  -22.172 1.00 51.51  ? 190 PHE B N   1 
ATOM 4118 C CA  . PHE D 4 54  ? -76.485  24.462  -23.287 1.00 52.02  ? 190 PHE B CA  1 
ATOM 4119 C C   . PHE D 4 54  ? -75.557  25.288  -24.165 1.00 59.39  ? 190 PHE B C   1 
ATOM 4120 O O   . PHE D 4 54  ? -74.685  26.005  -23.662 1.00 55.18  ? 190 PHE B O   1 
ATOM 4121 C CB  . PHE D 4 54  ? -77.630  25.356  -22.808 1.00 54.21  ? 190 PHE B CB  1 
ATOM 4122 C CG  . PHE D 4 54  ? -78.930  24.640  -22.629 1.00 52.53  ? 190 PHE B CG  1 
ATOM 4123 C CD1 . PHE D 4 54  ? -79.114  23.765  -21.573 1.00 57.20  ? 190 PHE B CD1 1 
ATOM 4124 C CD2 . PHE D 4 54  ? -79.977  24.854  -23.513 1.00 53.98  ? 190 PHE B CD2 1 
ATOM 4125 C CE1 . PHE D 4 54  ? -80.318  23.113  -21.400 1.00 72.64  ? 190 PHE B CE1 1 
ATOM 4126 C CE2 . PHE D 4 54  ? -81.183  24.200  -23.349 1.00 63.10  ? 190 PHE B CE2 1 
ATOM 4127 C CZ  . PHE D 4 54  ? -81.354  23.329  -22.290 1.00 74.60  ? 190 PHE B CZ  1 
ATOM 4128 N N   . LYS D 4 55  ? -75.756  25.181  -25.476 1.00 51.83  ? 191 LYS B N   1 
ATOM 4129 C CA  . LYS D 4 55  ? -75.198  26.109  -26.456 1.00 43.53  ? 191 LYS B CA  1 
ATOM 4130 C C   . LYS D 4 55  ? -76.374  26.930  -26.974 1.00 51.59  ? 191 LYS B C   1 
ATOM 4131 O O   . LYS D 4 55  ? -77.169  26.447  -27.784 1.00 54.65  ? 191 LYS B O   1 
ATOM 4132 C CB  . LYS D 4 55  ? -74.481  25.369  -27.583 1.00 51.73  ? 191 LYS B CB  1 
ATOM 4133 C CG  . LYS D 4 55  ? -73.799  26.278  -28.596 1.00 55.02  ? 191 LYS B CG  1 
ATOM 4134 C CD  . LYS D 4 55  ? -72.717  25.541  -29.382 1.00 62.72  ? 191 LYS B CD  1 
ATOM 4135 C CE  . LYS D 4 55  ? -73.311  24.521  -30.339 1.00 87.52  ? 191 LYS B CE  1 
ATOM 4136 N NZ  . LYS D 4 55  ? -72.258  23.799  -31.108 1.00 91.62  ? 191 LYS B NZ  1 
ATOM 4137 N N   . VAL D 4 56  ? -76.496  28.166  -26.487 1.00 44.34  ? 192 VAL B N   1 
ATOM 4138 C CA  . VAL D 4 56  ? -77.644  28.997  -26.835 1.00 52.62  ? 192 VAL B CA  1 
ATOM 4139 C C   . VAL D 4 56  ? -77.414  29.861  -28.069 1.00 47.94  ? 192 VAL B C   1 
ATOM 4140 O O   . VAL D 4 56  ? -78.387  30.344  -28.666 1.00 44.56  ? 192 VAL B O   1 
ATOM 4141 C CB  . VAL D 4 56  ? -78.033  29.902  -25.655 1.00 34.88  ? 192 VAL B CB  1 
ATOM 4142 C CG1 . VAL D 4 56  ? -78.520  29.064  -24.489 1.00 43.30  ? 192 VAL B CG1 1 
ATOM 4143 C CG2 . VAL D 4 56  ? -76.845  30.758  -25.246 1.00 32.19  ? 192 VAL B CG2 1 
ATOM 4144 N N   . LEU D 4 57  ? -76.164  30.074  -28.467 1.00 43.77  ? 193 LEU B N   1 
ATOM 4145 C CA  . LEU D 4 57  ? -75.864  30.951  -29.588 1.00 47.02  ? 193 LEU B CA  1 
ATOM 4146 C C   . LEU D 4 57  ? -74.542  30.519  -30.198 1.00 60.87  ? 193 LEU B C   1 
ATOM 4147 O O   . LEU D 4 57  ? -73.575  30.263  -29.472 1.00 51.09  ? 193 LEU B O   1 
ATOM 4148 C CB  . LEU D 4 57  ? -75.806  32.416  -29.141 1.00 41.70  ? 193 LEU B CB  1 
ATOM 4149 C CG  . LEU D 4 57  ? -75.559  33.466  -30.223 1.00 57.48  ? 193 LEU B CG  1 
ATOM 4150 C CD1 . LEU D 4 57  ? -76.636  33.396  -31.294 1.00 70.97  ? 193 LEU B CD1 1 
ATOM 4151 C CD2 . LEU D 4 57  ? -75.499  34.855  -29.612 1.00 57.53  ? 193 LEU B CD2 1 
ATOM 4152 N N   . ASP D 4 58  ? -74.510  30.426  -31.526 1.00 57.70  ? 194 ASP B N   1 
ATOM 4153 C CA  . ASP D 4 58  ? -73.323  30.015  -32.272 1.00 60.15  ? 194 ASP B CA  1 
ATOM 4154 C C   . ASP D 4 58  ? -72.931  31.164  -33.194 1.00 67.57  ? 194 ASP B C   1 
ATOM 4155 O O   . ASP D 4 58  ? -73.312  31.201  -34.366 1.00 72.58  ? 194 ASP B O   1 
ATOM 4156 C CB  . ASP D 4 58  ? -73.592  28.709  -33.052 1.00 66.23  ? 194 ASP B CB  1 
ATOM 4157 C CG  . ASP D 4 58  ? -72.314  27.982  -33.441 1.00 81.73  ? 194 ASP B CG  1 
ATOM 4158 O OD1 . ASP D 4 58  ? -71.250  28.633  -33.515 1.00 72.68  ? 194 ASP B OD1 1 
ATOM 4159 O OD2 . ASP D 4 58  ? -72.373  26.752  -33.661 1.00 92.94  ? 194 ASP B OD2 1 
ATOM 4160 N N   . LEU D 4 59  ? -72.164  32.110  -32.651 1.00 71.45  ? 195 LEU B N   1 
ATOM 4161 C CA  . LEU D 4 59  ? -71.643  33.201  -33.465 1.00 64.49  ? 195 LEU B CA  1 
ATOM 4162 C C   . LEU D 4 59  ? -70.470  32.746  -34.323 1.00 63.70  ? 195 LEU B C   1 
ATOM 4163 O O   . LEU D 4 59  ? -70.229  33.325  -35.387 1.00 73.80  ? 195 LEU B O   1 
ATOM 4164 C CB  . LEU D 4 59  ? -71.233  34.374  -32.571 1.00 57.96  ? 195 LEU B CB  1 
ATOM 4165 C CG  . LEU D 4 59  ? -72.403  35.206  -32.037 1.00 67.74  ? 195 LEU B CG  1 
ATOM 4166 C CD1 . LEU D 4 59  ? -71.912  36.395  -31.230 1.00 60.58  ? 195 LEU B CD1 1 
ATOM 4167 C CD2 . LEU D 4 59  ? -73.301  35.665  -33.179 1.00 73.19  ? 195 LEU B CD2 1 
ATOM 4168 N N   . LYS D 4 60  ? -69.738  31.719  -33.884 1.00 60.08  ? 196 LYS B N   1 
ATOM 4169 C CA  . LYS D 4 60  ? -68.649  31.182  -34.695 1.00 70.85  ? 196 LYS B CA  1 
ATOM 4170 C C   . LYS D 4 60  ? -69.168  30.658  -36.026 1.00 77.97  ? 196 LYS B C   1 
ATOM 4171 O O   . LYS D 4 60  ? -68.617  30.969  -37.089 1.00 66.38  ? 196 LYS B O   1 
ATOM 4172 C CB  . LYS D 4 60  ? -67.927  30.072  -33.931 1.00 73.52  ? 196 LYS B CB  1 
ATOM 4173 C CG  . LYS D 4 60  ? -66.764  29.446  -34.687 1.00 70.10  ? 196 LYS B CG  1 
ATOM 4174 C CD  . LYS D 4 60  ? -66.163  28.296  -33.894 1.00 87.50  ? 196 LYS B CD  1 
ATOM 4175 C CE  . LYS D 4 60  ? -64.844  27.833  -34.488 1.00 93.73  ? 196 LYS B CE  1 
ATOM 4176 N NZ  . LYS D 4 60  ? -64.211  26.777  -33.646 1.00 93.71  ? 196 LYS B NZ  1 
ATOM 4177 N N   . ASN D 4 61  ? -70.237  29.861  -35.986 1.00 84.69  ? 197 ASN B N   1 
ATOM 4178 C CA  . ASN D 4 61  ? -70.817  29.333  -37.215 1.00 73.95  ? 197 ASN B CA  1 
ATOM 4179 C C   . ASN D 4 61  ? -71.380  30.459  -38.076 1.00 72.99  ? 197 ASN B C   1 
ATOM 4180 O O   . ASN D 4 61  ? -71.161  30.486  -39.292 1.00 78.90  ? 197 ASN B O   1 
ATOM 4181 C CB  . ASN D 4 61  ? -71.887  28.291  -36.867 1.00 78.57  ? 197 ASN B CB  1 
ATOM 4182 C CG  . ASN D 4 61  ? -72.553  27.666  -38.094 1.00 77.90  ? 197 ASN B CG  1 
ATOM 4183 O OD1 . ASN D 4 61  ? -72.860  28.335  -39.079 1.00 68.32  ? 197 ASN B OD1 1 
ATOM 4184 N ND2 . ASN D 4 61  ? -72.769  26.357  -38.030 1.00 85.94  ? 197 ASN B ND2 1 
ATOM 4185 N N   . TYR D 4 62  ? -72.071  31.423  -37.481 1.00 82.88  ? 198 TYR B N   1 
ATOM 4186 C CA  . TYR D 4 62  ? -72.733  32.454  -38.329 1.00 80.62  ? 198 TYR B CA  1 
ATOM 4187 C C   . TYR D 4 62  ? -71.709  33.397  -38.947 1.00 76.29  ? 198 TYR B C   1 
ATOM 4188 O O   . TYR D 4 62  ? -72.037  33.995  -39.967 1.00 79.89  ? 198 TYR B O   1 
ATOM 4189 C CB  . TYR D 4 62  ? -73.771  33.289  -37.574 1.00 77.89  ? 198 TYR B CB  1 
ATOM 4190 C CG  . TYR D 4 62  ? -74.449  34.355  -38.422 1.00 69.39  ? 198 TYR B CG  1 
ATOM 4191 C CD1 . TYR D 4 62  ? -75.521  34.041  -39.246 1.00 69.77  ? 198 TYR B CD1 1 
ATOM 4192 C CD2 . TYR D 4 62  ? -74.004  35.670  -38.410 1.00 71.47  ? 198 TYR B CD2 1 
ATOM 4193 C CE1 . TYR D 4 62  ? -76.134  35.004  -40.029 1.00 76.42  ? 198 TYR B CE1 1 
ATOM 4194 C CE2 . TYR D 4 62  ? -74.603  36.639  -39.193 1.00 74.44  ? 198 TYR B CE2 1 
ATOM 4195 C CZ  . TYR D 4 62  ? -75.673  36.307  -40.001 1.00 80.50  ? 198 TYR B CZ  1 
ATOM 4196 O OH  . TYR D 4 62  ? -76.267  37.264  -40.769 1.00 86.45  ? 198 TYR B OH  1 
ATOM 4197 N N   . ILE D 4 63  ? -70.544  33.573  -38.335 1.00 79.12  ? 199 ILE B N   1 
ATOM 4198 C CA  . ILE D 4 63  ? -69.579  34.576  -38.870 1.00 67.02  ? 199 ILE B CA  1 
ATOM 4199 C C   . ILE D 4 63  ? -68.690  33.885  -39.898 1.00 74.64  ? 199 ILE B C   1 
ATOM 4200 O O   . ILE D 4 63  ? -68.370  34.515  -40.908 1.00 83.23  ? 199 ILE B O   1 
ATOM 4201 C CB  . ILE D 4 63  ? -68.743  35.195  -37.735 1.00 76.99  ? 199 ILE B CB  1 
ATOM 4202 C CG1 . ILE D 4 63  ? -69.566  36.161  -36.881 1.00 66.49  ? 199 ILE B CG1 1 
ATOM 4203 C CG2 . ILE D 4 63  ? -67.491  35.861  -38.281 1.00 59.73  ? 199 ILE B CG2 1 
ATOM 4204 C CD1 . ILE D 4 63  ? -68.855  36.618  -35.632 1.00 55.05  ? 199 ILE B CD1 1 
ATOM 4205 N N   . ASP D 4 64  ? -68.331  32.629  -39.648 1.00 84.14  ? 200 ASP B N   1 
ATOM 4206 C CA  . ASP D 4 64  ? -67.396  31.912  -40.549 1.00 69.22  ? 200 ASP B CA  1 
ATOM 4207 C C   . ASP D 4 64  ? -68.152  31.353  -41.755 1.00 77.41  ? 200 ASP B C   1 
ATOM 4208 O O   . ASP D 4 64  ? -67.641  31.498  -42.872 1.00 91.22  ? 200 ASP B O   1 
ATOM 4209 C CB  . ASP D 4 64  ? -66.637  30.833  -39.781 1.00 75.14  ? 200 ASP B CB  1 
ATOM 4210 C CG  . ASP D 4 64  ? -65.670  31.397  -38.757 1.00 85.06  ? 200 ASP B CG  1 
ATOM 4211 O OD1 . ASP D 4 64  ? -65.487  32.628  -38.743 1.00 84.88  ? 200 ASP B OD1 1 
ATOM 4212 O OD2 . ASP D 4 64  ? -65.110  30.601  -37.982 1.00 96.45  ? 200 ASP B OD2 1 
ATOM 4213 N N   . LYS D 4 65  ? -69.312  30.736  -41.539 1.00 83.61  ? 201 LYS B N   1 
ATOM 4214 C CA  . LYS D 4 65  ? -70.131  30.242  -42.678 1.00 81.51  ? 201 LYS B CA  1 
ATOM 4215 C C   . LYS D 4 65  ? -70.764  31.442  -43.378 1.00 76.01  ? 201 LYS B C   1 
ATOM 4216 O O   . LYS D 4 65  ? -70.116  32.006  -44.267 1.00 95.81  ? 201 LYS B O   1 
ATOM 4217 C CB  . LYS D 4 65  ? -71.200  29.259  -42.198 1.00 83.31  ? 201 LYS B CB  1 
ATOM 4218 C CG  . LYS D 4 65  ? -70.953  27.800  -42.559 1.00 93.39  ? 201 LYS B CG  1 
ATOM 4219 C CD  . LYS D 4 65  ? -71.977  26.844  -41.982 1.00 85.66  ? 201 LYS B CD  1 
ATOM 4220 C CE  . LYS D 4 65  ? -73.406  27.215  -42.320 1.00 92.80  ? 201 LYS B CE  1 
ATOM 4221 N NZ  . LYS D 4 65  ? -74.377  26.555  -41.416 1.00 79.54  ? 201 LYS B NZ  1 
ATOM 4222 N N   . GLN D 4 66  ? -71.985  31.813  -42.999 1.00 82.03  ? 202 GLN B N   1 
ATOM 4223 C CA  . GLN D 4 66  ? -72.566  33.053  -43.572 1.00 82.73  ? 202 GLN B CA  1 
ATOM 4224 C C   . GLN D 4 66  ? -71.617  34.189  -43.193 1.00 90.09  ? 202 GLN B C   1 
ATOM 4225 O O   . GLN D 4 66  ? -70.925  34.036  -42.184 1.00 109.36 ? 202 GLN B O   1 
ATOM 4226 C CB  . GLN D 4 66  ? -73.977  33.292  -43.038 1.00 74.84  ? 202 GLN B CB  1 
ATOM 4227 C CG  . GLN D 4 66  ? -74.965  32.197  -43.404 1.00 78.92  ? 202 GLN B CG  1 
ATOM 4228 C CD  . GLN D 4 66  ? -75.248  31.287  -42.235 1.00 99.43  ? 202 GLN B CD  1 
ATOM 4229 O OE1 . GLN D 4 66  ? -74.368  30.583  -41.747 1.00 100.88 ? 202 GLN B OE1 1 
ATOM 4230 N NE2 . GLN D 4 66  ? -76.488  31.297  -41.775 1.00 100.06 ? 202 GLN B NE2 1 
ATOM 4231 N N   . LEU D 4 67  ? -71.524  35.242  -44.003 1.00 66.78  ? 203 LEU B N   1 
ATOM 4232 C CA  . LEU D 4 67  ? -70.566  36.348  -43.738 1.00 78.88  ? 203 LEU B CA  1 
ATOM 4233 C C   . LEU D 4 67  ? -69.135  35.816  -43.838 1.00 94.88  ? 203 LEU B C   1 
ATOM 4234 O O   . LEU D 4 67  ? -68.944  34.594  -43.797 1.00 106.97 ? 203 LEU B O   1 
ATOM 4235 C CB  . LEU D 4 67  ? -70.835  36.944  -42.355 1.00 77.55  ? 203 LEU B CB  1 
ATOM 4236 C CG  . LEU D 4 67  ? -71.169  38.433  -42.318 1.00 76.59  ? 203 LEU B CG  1 
ATOM 4237 C CD1 . LEU D 4 67  ? -71.112  38.957  -40.893 1.00 80.39  ? 203 LEU B CD1 1 
ATOM 4238 C CD2 . LEU D 4 67  ? -70.222  39.220  -43.209 1.00 90.39  ? 203 LEU B CD2 1 
ATOM 4239 N N   . LEU D 4 68  ? -68.169  36.703  -44.057 1.00 92.70  ? 204 LEU B N   1 
ATOM 4240 C CA  . LEU D 4 68  ? -66.735  36.308  -44.149 1.00 111.26 ? 204 LEU B CA  1 
ATOM 4241 C C   . LEU D 4 68  ? -66.401  35.382  -45.329 1.00 114.02 ? 204 LEU B C   1 
ATOM 4242 O O   . LEU D 4 68  ? -65.381  34.684  -45.210 1.00 107.37 ? 204 LEU B O   1 
ATOM 4243 C CB  . LEU D 4 68  ? -66.305  35.674  -42.824 1.00 103.43 ? 204 LEU B CB  1 
ATOM 4244 C CG  . LEU D 4 68  ? -65.294  36.490  -42.024 1.00 111.22 ? 204 LEU B CG  1 
ATOM 4245 C CD1 . LEU D 4 68  ? -65.959  37.707  -41.400 1.00 77.79  ? 204 LEU B CD1 1 
ATOM 4246 C CD2 . LEU D 4 68  ? -64.626  35.634  -40.960 1.00 114.46 ? 204 LEU B CD2 1 
ATOM 4247 N N   . PRO D 4 69  ? -67.158  35.292  -46.448 1.00 127.42 ? 205 PRO B N   1 
ATOM 4248 C CA  . PRO D 4 69  ? -66.764  34.564  -47.641 1.00 126.20 ? 205 PRO B CA  1 
ATOM 4249 C C   . PRO D 4 69  ? -66.873  35.724  -48.635 1.00 128.95 ? 205 PRO B C   1 
ATOM 4250 O O   . PRO D 4 69  ? -67.546  35.575  -49.638 1.00 138.98 ? 205 PRO B O   1 
ATOM 4251 C CB  . PRO D 4 69  ? -67.935  33.589  -47.712 1.00 133.16 ? 205 PRO B CB  1 
ATOM 4252 C CG  . PRO D 4 69  ? -69.129  34.413  -47.250 1.00 124.11 ? 205 PRO B CG  1 
ATOM 4253 C CD  . PRO D 4 69  ? -68.542  35.695  -46.692 1.00 128.38 ? 205 PRO B CD  1 
ATOM 4254 N N   . ILE D 4 70  ? -66.186  36.838  -48.356 1.00 129.00 ? 206 ILE B N   1 
ATOM 4255 C CA  . ILE D 4 70  ? -66.385  38.078  -49.166 1.00 145.66 ? 206 ILE B CA  1 
ATOM 4256 C C   . ILE D 4 70  ? -65.310  38.286  -50.242 1.00 159.70 ? 206 ILE B C   1 
ATOM 4257 O O   . ILE D 4 70  ? -65.321  39.377  -50.843 1.00 160.69 ? 206 ILE B O   1 
ATOM 4258 C CB  . ILE D 4 70  ? -66.448  39.285  -48.211 1.00 133.65 ? 206 ILE B CB  1 
ATOM 4259 C CG1 . ILE D 4 70  ? -65.233  39.323  -47.281 1.00 114.40 ? 206 ILE B CG1 1 
ATOM 4260 C CG2 . ILE D 4 70  ? -67.752  39.291  -47.431 1.00 110.75 ? 206 ILE B CG2 1 
ATOM 4261 C CD1 . ILE D 4 70  ? -65.567  39.670  -45.852 1.00 122.04 ? 206 ILE B CD1 1 
ATOM 4262 N N   . LEU D 4 71  ? -64.434  37.309  -50.488 1.00 158.72 ? 207 LEU B N   1 
ATOM 4263 C CA  . LEU D 4 71  ? -63.451  37.449  -51.597 1.00 158.24 ? 207 LEU B CA  1 
ATOM 4264 C C   . LEU D 4 71  ? -62.754  38.804  -51.472 1.00 170.72 ? 207 LEU B C   1 
ATOM 4265 O O   . LEU D 4 71  ? -62.998  39.671  -52.338 1.00 163.48 ? 207 LEU B O   1 
ATOM 4266 C CB  . LEU D 4 71  ? -64.205  37.344  -52.925 1.00 153.86 ? 207 LEU B CB  1 
ATOM 4267 C CG  . LEU D 4 71  ? -63.434  36.689  -54.070 1.00 150.80 ? 207 LEU B CG  1 
ATOM 4268 C CD1 . LEU D 4 71  ? -62.717  35.436  -53.593 1.00 143.87 ? 207 LEU B CD1 1 
ATOM 4269 C CD2 . LEU D 4 71  ? -64.362  36.365  -55.230 1.00 112.81 ? 207 LEU B CD2 1 
ATOM 4270 N N   . ASN D 4 72  ? -61.884  38.965  -50.471 1.00 179.79 ? 208 ASN B N   1 
ATOM 4271 C CA  . ASN D 4 72  ? -61.282  40.269  -50.221 1.00 176.96 ? 208 ASN B CA  1 
ATOM 4272 C C   . ASN D 4 72  ? -60.136  40.538  -51.189 1.00 183.29 ? 208 ASN B C   1 
ATOM 4273 O O   . ASN D 4 72  ? -58.989  40.734  -50.771 1.00 187.46 ? 208 ASN B O   1 
ATOM 4274 C CB  . ASN D 4 72  ? -60.792  40.365  -48.773 1.00 154.82 ? 208 ASN B CB  1 
ATOM 4275 C CG  . ASN D 4 72  ? -60.490  41.793  -48.353 1.00 159.02 ? 208 ASN B CG  1 
ATOM 4276 O OD1 . ASN D 4 72  ? -60.845  42.745  -49.049 1.00 166.52 ? 208 ASN B OD1 1 
ATOM 4277 N ND2 . ASN D 4 72  ? -59.824  41.947  -47.215 1.00 154.45 ? 208 ASN B ND2 1 
ATOM 4278 N N   . LYS D 4 73  ? -60.445  40.546  -52.488 1.00 181.28 ? 209 LYS B N   1 
ATOM 4279 C CA  . LYS D 4 73  ? -59.520  41.003  -53.524 1.00 182.93 ? 209 LYS B CA  1 
ATOM 4280 C C   . LYS D 4 73  ? -59.615  42.530  -53.580 1.00 192.83 ? 209 LYS B C   1 
ATOM 4281 O O   . LYS D 4 73  ? -60.154  43.130  -54.512 1.00 194.52 ? 209 LYS B O   1 
ATOM 4282 C CB  . LYS D 4 73  ? -59.856  40.356  -54.863 1.00 160.82 ? 209 LYS B CB  1 
ATOM 4283 C CG  . LYS D 4 73  ? -58.808  40.512  -55.971 1.00 148.21 ? 209 LYS B CG  1 
ATOM 4284 C CD  . LYS D 4 73  ? -59.057  41.734  -56.853 1.00 143.48 ? 209 LYS B CD  1 
ATOM 4285 C CE  . LYS D 4 73  ? -60.214  41.512  -57.819 1.00 131.62 ? 209 LYS B CE  1 
ATOM 4286 N NZ  . LYS D 4 73  ? -60.494  42.703  -58.674 1.00 107.81 ? 209 LYS B NZ  1 
ATOM 4287 N N   . GLN D 4 74  ? -59.148  43.160  -52.500 1.00 190.91 ? 210 GLN B N   1 
ATOM 4288 C CA  . GLN D 4 74  ? -59.201  44.603  -52.261 1.00 186.20 ? 210 GLN B CA  1 
ATOM 4289 C C   . GLN D 4 74  ? -60.643  45.086  -52.091 1.00 186.01 ? 210 GLN B C   1 
ATOM 4290 O O   . GLN D 4 74  ? -60.859  46.223  -51.660 1.00 187.00 ? 210 GLN B O   1 
ATOM 4291 C CB  . GLN D 4 74  ? -58.456  45.386  -53.362 1.00 180.97 ? 210 GLN B CB  1 
ATOM 4292 C CG  . GLN D 4 74  ? -58.852  46.834  -53.646 1.00 172.54 ? 210 GLN B CG  1 
ATOM 4293 C CD  . GLN D 4 74  ? -58.050  47.412  -54.798 1.00 164.74 ? 210 GLN B CD  1 
ATOM 4294 O OE1 . GLN D 4 74  ? -57.200  46.727  -55.368 1.00 165.11 ? 210 GLN B OE1 1 
ATOM 4295 N NE2 . GLN D 4 74  ? -58.315  48.669  -55.149 1.00 152.04 ? 210 GLN B NE2 1 
ATOM 4296 N N   . SER D 4 75  ? -61.635  44.221  -52.308 1.00 188.04 ? 211 SER B N   1 
ATOM 4297 C CA  . SER D 4 75  ? -63.035  44.624  -52.275 1.00 186.01 ? 211 SER B CA  1 
ATOM 4298 C C   . SER D 4 75  ? -63.726  44.262  -50.964 1.00 180.36 ? 211 SER B C   1 
ATOM 4299 O O   . SER D 4 75  ? -64.244  45.145  -50.273 1.00 174.83 ? 211 SER B O   1 
ATOM 4300 C CB  . SER D 4 75  ? -63.784  43.980  -53.446 1.00 172.80 ? 211 SER B CB  1 
ATOM 4301 O OG  . SER D 4 75  ? -63.671  42.567  -53.391 1.00 160.73 ? 211 SER B OG  1 
ATOM 4302 N N   . CYS D 4 76  ? -63.777  42.967  -50.632 1.00 175.88 ? 212 CYS B N   1 
ATOM 4303 C CA  . CYS D 4 76  ? -64.520  42.453  -49.481 1.00 165.71 ? 212 CYS B CA  1 
ATOM 4304 C C   . CYS D 4 76  ? -66.009  42.784  -49.589 1.00 161.74 ? 212 CYS B C   1 
ATOM 4305 O O   . CYS D 4 76  ? -66.802  42.419  -48.713 1.00 155.11 ? 212 CYS B O   1 
ATOM 4306 C CB  . CYS D 4 76  ? -63.919  42.987  -48.171 1.00 156.25 ? 212 CYS B CB  1 
ATOM 4307 S SG  . CYS D 4 76  ? -64.937  44.140  -47.211 1.00 186.29 ? 212 CYS B SG  1 
ATOM 4308 N N   . SER D 4 77  ? -66.405  43.416  -50.694 1.00 170.22 ? 213 SER B N   1 
ATOM 4309 C CA  . SER D 4 77  ? -67.726  44.032  -50.828 1.00 165.07 ? 213 SER B CA  1 
ATOM 4310 C C   . SER D 4 77  ? -68.766  43.018  -51.309 1.00 164.33 ? 213 SER B C   1 
ATOM 4311 O O   . SER D 4 77  ? -69.439  43.199  -52.323 1.00 160.87 ? 213 SER B O   1 
ATOM 4312 C CB  . SER D 4 77  ? -67.648  45.228  -51.769 1.00 159.03 ? 213 SER B CB  1 
ATOM 4313 O OG  . SER D 4 77  ? -67.129  44.845  -53.031 1.00 158.48 ? 213 SER B OG  1 
ATOM 4314 N N   . ILE D 4 78  ? -68.891  41.936  -50.548 1.00 160.65 ? 214 ILE B N   1 
ATOM 4315 C CA  . ILE D 4 78  ? -69.960  40.961  -50.727 1.00 155.86 ? 214 ILE B CA  1 
ATOM 4316 C C   . ILE D 4 78  ? -70.906  41.134  -49.551 1.00 146.84 ? 214 ILE B C   1 
ATOM 4317 O O   . ILE D 4 78  ? -70.539  40.852  -48.403 1.00 151.04 ? 214 ILE B O   1 
ATOM 4318 C CB  . ILE D 4 78  ? -69.426  39.525  -50.804 1.00 154.50 ? 214 ILE B CB  1 
ATOM 4319 C CG1 . ILE D 4 78  ? -68.495  39.368  -52.006 1.00 146.72 ? 214 ILE B CG1 1 
ATOM 4320 C CG2 . ILE D 4 78  ? -70.583  38.539  -50.874 1.00 142.88 ? 214 ILE B CG2 1 
ATOM 4321 C CD1 . ILE D 4 78  ? -68.308  37.935  -52.455 1.00 138.06 ? 214 ILE B CD1 1 
ATOM 4322 N N   . SER D 4 79  ? -72.123  41.595  -49.824 1.00 139.19 ? 215 SER B N   1 
ATOM 4323 C CA  . SER D 4 79  ? -73.017  41.950  -48.735 1.00 137.45 ? 215 SER B CA  1 
ATOM 4324 C C   . SER D 4 79  ? -74.452  42.025  -49.236 1.00 134.14 ? 215 SER B C   1 
ATOM 4325 O O   . SER D 4 79  ? -74.706  42.256  -50.422 1.00 125.75 ? 215 SER B O   1 
ATOM 4326 C CB  . SER D 4 79  ? -72.592  43.279  -48.094 1.00 132.51 ? 215 SER B CB  1 
ATOM 4327 O OG  . SER D 4 79  ? -72.265  44.247  -49.079 1.00 122.17 ? 215 SER B OG  1 
ATOM 4328 N N   . ASN D 4 80  ? -75.382  41.815  -48.306 1.00 132.10 ? 216 ASN B N   1 
ATOM 4329 C CA  . ASN D 4 80  ? -76.813  41.977  -48.521 1.00 120.39 ? 216 ASN B CA  1 
ATOM 4330 C C   . ASN D 4 80  ? -77.386  42.557  -47.239 1.00 110.80 ? 216 ASN B C   1 
ATOM 4331 O O   . ASN D 4 80  ? -77.070  42.066  -46.152 1.00 111.24 ? 216 ASN B O   1 
ATOM 4332 C CB  . ASN D 4 80  ? -77.479  40.636  -48.863 1.00 106.47 ? 216 ASN B CB  1 
ATOM 4333 C CG  . ASN D 4 80  ? -78.919  40.789  -49.309 1.00 108.14 ? 216 ASN B CG  1 
ATOM 4334 O OD1 . ASN D 4 80  ? -79.433  41.902  -49.420 1.00 108.99 ? 216 ASN B OD1 1 
ATOM 4335 N ND2 . ASN D 4 80  ? -79.577  39.665  -49.578 1.00 105.97 ? 216 ASN B ND2 1 
ATOM 4336 N N   . ILE D 4 81  ? -78.215  43.599  -47.352 1.00 92.31  ? 217 ILE B N   1 
ATOM 4337 C CA  . ILE D 4 81  ? -78.713  44.262  -46.149 1.00 87.42  ? 217 ILE B CA  1 
ATOM 4338 C C   . ILE D 4 81  ? -79.435  43.286  -45.232 1.00 88.94  ? 217 ILE B C   1 
ATOM 4339 O O   . ILE D 4 81  ? -79.560  43.545  -44.030 1.00 93.71  ? 217 ILE B O   1 
ATOM 4340 C CB  . ILE D 4 81  ? -79.614  45.463  -46.505 1.00 82.00  ? 217 ILE B CB  1 
ATOM 4341 C CG1 . ILE D 4 81  ? -79.431  46.580  -45.479 1.00 63.18  ? 217 ILE B CG1 1 
ATOM 4342 C CG2 . ILE D 4 81  ? -81.076  45.070  -46.521 1.00 77.31  ? 217 ILE B CG2 1 
ATOM 4343 C CD1 . ILE D 4 81  ? -78.006  47.036  -45.313 1.00 86.81  ? 217 ILE B CD1 1 
ATOM 4344 N N   . GLU D 4 82  ? -79.899  42.155  -45.766 1.00 92.70  ? 218 GLU B N   1 
ATOM 4345 C CA  . GLU D 4 82  ? -80.513  41.138  -44.920 1.00 86.55  ? 218 GLU B CA  1 
ATOM 4346 C C   . GLU D 4 82  ? -79.505  40.566  -43.931 1.00 97.42  ? 218 GLU B C   1 
ATOM 4347 O O   . GLU D 4 82  ? -79.777  40.483  -42.727 1.00 99.80  ? 218 GLU B O   1 
ATOM 4348 C CB  . GLU D 4 82  ? -81.099  40.017  -45.774 1.00 100.44 ? 218 GLU B CB  1 
ATOM 4349 C CG  . GLU D 4 82  ? -81.557  40.404  -47.173 1.00 113.48 ? 218 GLU B CG  1 
ATOM 4350 C CD  . GLU D 4 82  ? -82.519  41.566  -47.185 1.00 113.25 ? 218 GLU B CD  1 
ATOM 4351 O OE1 . GLU D 4 82  ? -83.584  41.451  -46.550 1.00 112.11 ? 218 GLU B OE1 1 
ATOM 4352 O OE2 . GLU D 4 82  ? -82.234  42.570  -47.868 1.00 114.21 ? 218 GLU B OE2 1 
ATOM 4353 N N   . THR D 4 83  ? -78.332  40.157  -44.423 1.00 96.65  ? 219 THR B N   1 
ATOM 4354 C CA  . THR D 4 83  ? -77.341  39.564  -43.534 1.00 105.54 ? 219 THR B CA  1 
ATOM 4355 C C   . THR D 4 83  ? -76.726  40.599  -42.599 1.00 97.22  ? 219 THR B C   1 
ATOM 4356 O O   . THR D 4 83  ? -76.184  40.225  -41.553 1.00 91.01  ? 219 THR B O   1 
ATOM 4357 C CB  . THR D 4 83  ? -76.251  38.847  -44.342 1.00 104.18 ? 219 THR B CB  1 
ATOM 4358 O OG1 . THR D 4 83  ? -75.491  37.993  -43.476 1.00 91.50  ? 219 THR B OG1 1 
ATOM 4359 C CG2 . THR D 4 83  ? -75.307  39.842  -44.990 1.00 102.74 ? 219 THR B CG2 1 
ATOM 4360 N N   . VAL D 4 84  ? -76.801  41.887  -42.948 1.00 83.85  ? 220 VAL B N   1 
ATOM 4361 C CA  . VAL D 4 84  ? -76.415  42.935  -42.007 1.00 85.86  ? 220 VAL B CA  1 
ATOM 4362 C C   . VAL D 4 84  ? -77.393  42.978  -40.837 1.00 77.25  ? 220 VAL B C   1 
ATOM 4363 O O   . VAL D 4 84  ? -76.991  43.034  -39.669 1.00 64.91  ? 220 VAL B O   1 
ATOM 4364 C CB  . VAL D 4 84  ? -76.330  44.295  -42.723 1.00 74.08  ? 220 VAL B CB  1 
ATOM 4365 C CG1 . VAL D 4 84  ? -76.519  45.441  -41.734 1.00 77.29  ? 220 VAL B CG1 1 
ATOM 4366 C CG2 . VAL D 4 84  ? -75.005  44.431  -43.443 1.00 81.35  ? 220 VAL B CG2 1 
ATOM 4367 N N   . ILE D 4 85  ? -78.694  42.945  -41.138 1.00 70.88  ? 221 ILE B N   1 
ATOM 4368 C CA  . ILE D 4 85  ? -79.709  42.918  -40.089 1.00 62.24  ? 221 ILE B CA  1 
ATOM 4369 C C   . ILE D 4 85  ? -79.620  41.617  -39.299 1.00 74.64  ? 221 ILE B C   1 
ATOM 4370 O O   . ILE D 4 85  ? -79.692  41.618  -38.064 1.00 70.94  ? 221 ILE B O   1 
ATOM 4371 C CB  . ILE D 4 85  ? -81.113  43.117  -40.694 1.00 62.94  ? 221 ILE B CB  1 
ATOM 4372 C CG1 . ILE D 4 85  ? -81.488  44.603  -40.777 1.00 61.84  ? 221 ILE B CG1 1 
ATOM 4373 C CG2 . ILE D 4 85  ? -82.162  42.371  -39.881 1.00 71.94  ? 221 ILE B CG2 1 
ATOM 4374 C CD1 . ILE D 4 85  ? -80.475  45.491  -41.466 1.00 56.37  ? 221 ILE B CD1 1 
ATOM 4375 N N   . GLU D 4 86  ? -79.451  40.489  -39.998 1.00 74.00  ? 222 GLU B N   1 
ATOM 4376 C CA  . GLU D 4 86  ? -79.371  39.197  -39.323 1.00 80.15  ? 222 GLU B CA  1 
ATOM 4377 C C   . GLU D 4 86  ? -78.185  39.140  -38.367 1.00 70.86  ? 222 GLU B C   1 
ATOM 4378 O O   . GLU D 4 86  ? -78.298  38.598  -37.261 1.00 73.23  ? 222 GLU B O   1 
ATOM 4379 C CB  . GLU D 4 86  ? -79.283  38.070  -40.354 1.00 89.46  ? 222 GLU B CB  1 
ATOM 4380 C CG  . GLU D 4 86  ? -80.497  37.147  -40.413 1.00 102.41 ? 222 GLU B CG  1 
ATOM 4381 C CD  . GLU D 4 86  ? -80.604  36.198  -39.226 1.00 115.26 ? 222 GLU B CD  1 
ATOM 4382 O OE1 . GLU D 4 86  ? -79.822  36.332  -38.261 1.00 107.75 ? 222 GLU B OE1 1 
ATOM 4383 O OE2 . GLU D 4 86  ? -81.477  35.307  -39.263 1.00 127.94 ? 222 GLU B OE2 1 
ATOM 4384 N N   . PHE D 4 87  ? -77.037  39.684  -38.778 1.00 71.61  ? 223 PHE B N   1 
ATOM 4385 C CA  . PHE D 4 87  ? -75.878  39.705  -37.891 1.00 64.67  ? 223 PHE B CA  1 
ATOM 4386 C C   . PHE D 4 87  ? -76.124  40.602  -36.685 1.00 68.36  ? 223 PHE B C   1 
ATOM 4387 O O   . PHE D 4 87  ? -75.691  40.285  -35.572 1.00 71.65  ? 223 PHE B O   1 
ATOM 4388 C CB  . PHE D 4 87  ? -74.635  40.155  -38.657 1.00 68.77  ? 223 PHE B CB  1 
ATOM 4389 C CG  . PHE D 4 87  ? -73.373  40.117  -37.841 1.00 68.51  ? 223 PHE B CG  1 
ATOM 4390 C CD1 . PHE D 4 87  ? -73.113  39.054  -36.991 1.00 67.04  ? 223 PHE B CD1 1 
ATOM 4391 C CD2 . PHE D 4 87  ? -72.437  41.131  -37.942 1.00 67.20  ? 223 PHE B CD2 1 
ATOM 4392 C CE1 . PHE D 4 87  ? -71.952  39.014  -36.243 1.00 57.96  ? 223 PHE B CE1 1 
ATOM 4393 C CE2 . PHE D 4 87  ? -71.271  41.096  -37.197 1.00 61.49  ? 223 PHE B CE2 1 
ATOM 4394 C CZ  . PHE D 4 87  ? -71.030  40.036  -36.347 1.00 55.03  ? 223 PHE B CZ  1 
ATOM 4395 N N   . GLN D 4 88  ? -76.819  41.723  -36.887 1.00 65.87  ? 224 GLN B N   1 
ATOM 4396 C CA  . GLN D 4 88  ? -77.181  42.582  -35.765 1.00 50.24  ? 224 GLN B CA  1 
ATOM 4397 C C   . GLN D 4 88  ? -78.085  41.848  -34.783 1.00 58.65  ? 224 GLN B C   1 
ATOM 4398 O O   . GLN D 4 88  ? -77.929  41.983  -33.564 1.00 67.33  ? 224 GLN B O   1 
ATOM 4399 C CB  . GLN D 4 88  ? -77.861  43.851  -36.277 1.00 49.53  ? 224 GLN B CB  1 
ATOM 4400 C CG  . GLN D 4 88  ? -76.900  44.877  -36.853 1.00 68.33  ? 224 GLN B CG  1 
ATOM 4401 C CD  . GLN D 4 88  ? -77.609  46.102  -37.403 1.00 80.76  ? 224 GLN B CD  1 
ATOM 4402 O OE1 . GLN D 4 88  ? -78.839  46.172  -37.408 1.00 80.61  ? 224 GLN B OE1 1 
ATOM 4403 N NE2 . GLN D 4 88  ? -76.834  47.079  -37.860 1.00 70.64  ? 224 GLN B NE2 1 
ATOM 4404 N N   . GLN D 4 89  ? -79.040  41.067  -35.295 1.00 64.28  ? 225 GLN B N   1 
ATOM 4405 C CA  . GLN D 4 89  ? -79.925  40.306  -34.419 1.00 57.05  ? 225 GLN B CA  1 
ATOM 4406 C C   . GLN D 4 89  ? -79.152  39.264  -33.619 1.00 64.12  ? 225 GLN B C   1 
ATOM 4407 O O   . GLN D 4 89  ? -79.370  39.110  -32.412 1.00 77.66  ? 225 GLN B O   1 
ATOM 4408 C CB  . GLN D 4 89  ? -81.029  39.634  -35.237 1.00 64.81  ? 225 GLN B CB  1 
ATOM 4409 C CG  . GLN D 4 89  ? -81.965  40.592  -35.959 1.00 72.31  ? 225 GLN B CG  1 
ATOM 4410 C CD  . GLN D 4 89  ? -82.393  41.764  -35.099 1.00 83.21  ? 225 GLN B CD  1 
ATOM 4411 O OE1 . GLN D 4 89  ? -83.052  41.591  -34.074 1.00 100.51 ? 225 GLN B OE1 1 
ATOM 4412 N NE2 . GLN D 4 89  ? -82.024  42.971  -35.519 1.00 76.83  ? 225 GLN B NE2 1 
ATOM 4413 N N   . LYS D 4 90  ? -78.246  38.534  -34.277 1.00 66.58  ? 226 LYS B N   1 
ATOM 4414 C CA  . LYS D 4 90  ? -77.471  37.512  -33.578 1.00 63.98  ? 226 LYS B CA  1 
ATOM 4415 C C   . LYS D 4 90  ? -76.487  38.135  -32.599 1.00 66.48  ? 226 LYS B C   1 
ATOM 4416 O O   . LYS D 4 90  ? -76.325  37.645  -31.475 1.00 77.55  ? 226 LYS B O   1 
ATOM 4417 C CB  . LYS D 4 90  ? -76.729  36.630  -34.583 1.00 74.96  ? 226 LYS B CB  1 
ATOM 4418 C CG  . LYS D 4 90  ? -77.594  35.562  -35.229 1.00 78.75  ? 226 LYS B CG  1 
ATOM 4419 C CD  . LYS D 4 90  ? -76.930  34.198  -35.161 1.00 73.92  ? 226 LYS B CD  1 
ATOM 4420 C CE  . LYS D 4 90  ? -77.833  33.121  -35.739 1.00 88.52  ? 226 LYS B CE  1 
ATOM 4421 N NZ  . LYS D 4 90  ? -78.967  32.810  -34.823 1.00 92.34  ? 226 LYS B NZ  1 
ATOM 4422 N N   . ASN D 4 91  ? -75.824  39.218  -33.005 1.00 63.95  ? 227 ASN B N   1 
ATOM 4423 C CA  . ASN D 4 91  ? -74.802  39.827  -32.165 1.00 57.03  ? 227 ASN B CA  1 
ATOM 4424 C C   . ASN D 4 91  ? -75.400  40.590  -30.990 1.00 63.54  ? 227 ASN B C   1 
ATOM 4425 O O   . ASN D 4 91  ? -74.702  40.812  -29.995 1.00 62.82  ? 227 ASN B O   1 
ATOM 4426 C CB  . ASN D 4 91  ? -73.930  40.754  -33.012 1.00 56.16  ? 227 ASN B CB  1 
ATOM 4427 C CG  . ASN D 4 91  ? -72.642  41.136  -32.323 1.00 62.44  ? 227 ASN B CG  1 
ATOM 4428 O OD1 . ASN D 4 91  ? -71.819  40.277  -32.000 1.00 60.65  ? 227 ASN B OD1 1 
ATOM 4429 N ND2 . ASN D 4 91  ? -72.448  42.432  -32.111 1.00 75.98  ? 227 ASN B ND2 1 
ATOM 4430 N N   . ASN D 4 92  ? -76.675  40.981  -31.076 1.00 61.91  ? 228 ASN B N   1 
ATOM 4431 C CA  . ASN D 4 92  ? -77.264  41.820  -30.036 1.00 64.40  ? 228 ASN B CA  1 
ATOM 4432 C C   . ASN D 4 92  ? -77.343  41.084  -28.704 1.00 65.21  ? 228 ASN B C   1 
ATOM 4433 O O   . ASN D 4 92  ? -77.131  41.686  -27.645 1.00 60.52  ? 228 ASN B O   1 
ATOM 4434 C CB  . ASN D 4 92  ? -78.647  42.307  -30.469 1.00 58.27  ? 228 ASN B CB  1 
ATOM 4435 C CG  . ASN D 4 92  ? -79.328  43.144  -29.404 1.00 79.08  ? 228 ASN B CG  1 
ATOM 4436 O OD1 . ASN D 4 92  ? -80.311  42.719  -28.797 1.00 91.94  ? 228 ASN B OD1 1 
ATOM 4437 N ND2 . ASN D 4 92  ? -78.799  44.340  -29.164 1.00 84.16  ? 228 ASN B ND2 1 
ATOM 4438 N N   . ARG D 4 93  ? -77.647  39.783  -28.734 1.00 66.06  ? 229 ARG B N   1 
ATOM 4439 C CA  . ARG D 4 93  ? -77.741  39.022  -27.491 1.00 52.12  ? 229 ARG B CA  1 
ATOM 4440 C C   . ARG D 4 93  ? -76.402  38.987  -26.767 1.00 49.44  ? 229 ARG B C   1 
ATOM 4441 O O   . ARG D 4 93  ? -76.349  39.111  -25.538 1.00 50.69  ? 229 ARG B O   1 
ATOM 4442 C CB  . ARG D 4 93  ? -78.234  37.604  -27.775 1.00 60.72  ? 229 ARG B CB  1 
ATOM 4443 C CG  . ARG D 4 93  ? -78.426  36.757  -26.525 1.00 28.24  ? 229 ARG B CG  1 
ATOM 4444 C CD  . ARG D 4 93  ? -79.119  35.450  -26.852 1.00 31.50  ? 229 ARG B CD  1 
ATOM 4445 N NE  . ARG D 4 93  ? -79.393  34.660  -25.659 1.00 44.61  ? 229 ARG B NE  1 
ATOM 4446 C CZ  . ARG D 4 93  ? -79.942  33.452  -25.667 1.00 51.02  ? 229 ARG B CZ  1 
ATOM 4447 N NH1 . ARG D 4 93  ? -80.266  32.847  -26.798 1.00 54.27  ? 229 ARG B NH1 1 
ATOM 4448 N NH2 . ARG D 4 93  ? -80.176  32.839  -24.511 1.00 52.00  ? 229 ARG B NH2 1 
ATOM 4449 N N   . LEU D 4 94  ? -75.307  38.816  -27.513 1.00 50.98  ? 230 LEU B N   1 
ATOM 4450 C CA  . LEU D 4 94  ? -73.986  38.883  -26.898 1.00 46.10  ? 230 LEU B CA  1 
ATOM 4451 C C   . LEU D 4 94  ? -73.723  40.262  -26.308 1.00 50.79  ? 230 LEU B C   1 
ATOM 4452 O O   . LEU D 4 94  ? -73.168  40.381  -25.210 1.00 57.39  ? 230 LEU B O   1 
ATOM 4453 C CB  . LEU D 4 94  ? -72.909  38.524  -27.919 1.00 44.88  ? 230 LEU B CB  1 
ATOM 4454 C CG  . LEU D 4 94  ? -71.481  38.574  -27.380 1.00 42.01  ? 230 LEU B CG  1 
ATOM 4455 C CD1 . LEU D 4 94  ? -71.270  37.488  -26.350 1.00 34.94  ? 230 LEU B CD1 1 
ATOM 4456 C CD2 . LEU D 4 94  ? -70.480  38.431  -28.517 1.00 47.38  ? 230 LEU B CD2 1 
ATOM 4457 N N   . LEU D 4 95  ? -74.121  41.316  -27.022 1.00 54.46  ? 231 LEU B N   1 
ATOM 4458 C CA  . LEU D 4 95  ? -73.918  42.671  -26.521 1.00 48.04  ? 231 LEU B CA  1 
ATOM 4459 C C   . LEU D 4 95  ? -74.701  42.909  -25.234 1.00 55.61  ? 231 LEU B C   1 
ATOM 4460 O O   . LEU D 4 95  ? -74.187  43.526  -24.293 1.00 59.65  ? 231 LEU B O   1 
ATOM 4461 C CB  . LEU D 4 95  ? -74.314  43.684  -27.595 1.00 51.71  ? 231 LEU B CB  1 
ATOM 4462 C CG  . LEU D 4 95  ? -73.461  43.666  -28.866 1.00 52.66  ? 231 LEU B CG  1 
ATOM 4463 C CD1 . LEU D 4 95  ? -73.950  44.705  -29.863 1.00 73.89  ? 231 LEU B CD1 1 
ATOM 4464 C CD2 . LEU D 4 95  ? -71.989  43.881  -28.540 1.00 50.41  ? 231 LEU B CD2 1 
ATOM 4465 N N   . GLU D 4 96  ? -75.948  42.430  -25.174 1.00 50.33  ? 232 GLU B N   1 
ATOM 4466 C CA  . GLU D 4 96  ? -76.761  42.619  -23.974 1.00 52.14  ? 232 GLU B CA  1 
ATOM 4467 C C   . GLU D 4 96  ? -76.208  41.831  -22.793 1.00 52.57  ? 232 GLU B C   1 
ATOM 4468 O O   . GLU D 4 96  ? -76.225  42.314  -21.655 1.00 53.47  ? 232 GLU B O   1 
ATOM 4469 C CB  . GLU D 4 96  ? -78.211  42.221  -24.251 1.00 55.16  ? 232 GLU B CB  1 
ATOM 4470 C CG  . GLU D 4 96  ? -78.954  43.180  -25.165 1.00 71.77  ? 232 GLU B CG  1 
ATOM 4471 C CD  . GLU D 4 96  ? -79.121  44.559  -24.551 1.00 87.77  ? 232 GLU B CD  1 
ATOM 4472 O OE1 . GLU D 4 96  ? -79.217  44.650  -23.307 1.00 92.43  ? 232 GLU B OE1 1 
ATOM 4473 O OE2 . GLU D 4 96  ? -79.151  45.551  -25.311 1.00 79.77  ? 232 GLU B OE2 1 
ATOM 4474 N N   . ILE D 4 97  ? -75.730  40.609  -23.040 1.00 51.04  ? 233 ILE B N   1 
ATOM 4475 C CA  . ILE D 4 97  ? -75.102  39.827  -21.978 1.00 43.22  ? 233 ILE B CA  1 
ATOM 4476 C C   . ILE D 4 97  ? -73.847  40.528  -21.472 1.00 55.46  ? 233 ILE B C   1 
ATOM 4477 O O   . ILE D 4 97  ? -73.608  40.607  -20.261 1.00 60.71  ? 233 ILE B O   1 
ATOM 4478 C CB  . ILE D 4 97  ? -74.805  38.399  -22.475 1.00 46.58  ? 233 ILE B CB  1 
ATOM 4479 C CG1 . ILE D 4 97  ? -76.104  37.601  -22.609 1.00 42.98  ? 233 ILE B CG1 1 
ATOM 4480 C CG2 . ILE D 4 97  ? -73.827  37.688  -21.554 1.00 44.30  ? 233 ILE B CG2 1 
ATOM 4481 C CD1 . ILE D 4 97  ? -75.892  36.173  -23.053 1.00 50.65  ? 233 ILE B CD1 1 
ATOM 4482 N N   . THR D 4 98  ? -73.033  41.058  -22.389 1.00 52.72  ? 234 THR B N   1 
ATOM 4483 C CA  . THR D 4 98  ? -71.843  41.798  -21.978 1.00 53.66  ? 234 THR B CA  1 
ATOM 4484 C C   . THR D 4 98  ? -72.214  43.053  -21.196 1.00 54.23  ? 234 THR B C   1 
ATOM 4485 O O   . THR D 4 98  ? -71.534  43.409  -20.226 1.00 50.76  ? 234 THR B O   1 
ATOM 4486 C CB  . THR D 4 98  ? -70.994  42.157  -23.197 1.00 47.91  ? 234 THR B CB  1 
ATOM 4487 O OG1 . THR D 4 98  ? -70.814  40.994  -24.014 1.00 60.89  ? 234 THR B OG1 1 
ATOM 4488 C CG2 . THR D 4 98  ? -69.633  42.676  -22.761 1.00 63.95  ? 234 THR B CG2 1 
ATOM 4489 N N   . ARG D 4 99  ? -73.283  43.744  -21.608 1.00 54.53  ? 235 ARG B N   1 
ATOM 4490 C CA  . ARG D 4 99  ? -73.726  44.930  -20.879 1.00 58.06  ? 235 ARG B CA  1 
ATOM 4491 C C   . ARG D 4 99  ? -74.101  44.584  -19.446 1.00 55.00  ? 235 ARG B C   1 
ATOM 4492 O O   . ARG D 4 99  ? -73.672  45.253  -18.500 1.00 55.26  ? 235 ARG B O   1 
ATOM 4493 C CB  . ARG D 4 99  ? -74.916  45.578  -21.586 1.00 53.13  ? 235 ARG B CB  1 
ATOM 4494 C CG  . ARG D 4 99  ? -74.554  46.577  -22.662 1.00 74.80  ? 235 ARG B CG  1 
ATOM 4495 C CD  . ARG D 4 99  ? -75.802  47.285  -23.176 1.00 76.31  ? 235 ARG B CD  1 
ATOM 4496 N NE  . ARG D 4 99  ? -76.092  46.946  -24.565 1.00 72.17  ? 235 ARG B NE  1 
ATOM 4497 C CZ  . ARG D 4 99  ? -75.523  47.530  -25.610 1.00 92.61  ? 235 ARG B CZ  1 
ATOM 4498 N NH1 . ARG D 4 99  ? -74.624  48.490  -25.460 1.00 99.37  ? 235 ARG B NH1 1 
ATOM 4499 N NH2 . ARG D 4 99  ? -75.864  47.144  -26.837 1.00 89.99  ? 235 ARG B NH2 1 
ATOM 4500 N N   . GLU D 4 100 ? -74.907  43.533  -19.272 1.00 54.32  ? 236 GLU B N   1 
ATOM 4501 C CA  . GLU D 4 100 ? -75.398  43.171  -17.947 1.00 50.77  ? 236 GLU B CA  1 
ATOM 4502 C C   . GLU D 4 100 ? -74.257  42.771  -17.019 1.00 58.66  ? 236 GLU B C   1 
ATOM 4503 O O   . GLU D 4 100 ? -74.224  43.177  -15.851 1.00 56.30  ? 236 GLU B O   1 
ATOM 4504 C CB  . GLU D 4 100 ? -76.417  42.039  -18.069 1.00 49.75  ? 236 GLU B CB  1 
ATOM 4505 C CG  . GLU D 4 100 ? -77.852  42.507  -18.217 1.00 56.63  ? 236 GLU B CG  1 
ATOM 4506 C CD  . GLU D 4 100 ? -78.827  41.353  -18.356 1.00 76.28  ? 236 GLU B CD  1 
ATOM 4507 O OE1 . GLU D 4 100 ? -79.075  40.655  -17.348 1.00 82.51  ? 236 GLU B OE1 1 
ATOM 4508 O OE2 . GLU D 4 100 ? -79.348  41.147  -19.473 1.00 67.01  ? 236 GLU B OE2 1 
ATOM 4509 N N   . PHE D 4 101 ? -73.308  41.978  -17.519 1.00 51.63  ? 237 PHE B N   1 
ATOM 4510 C CA  . PHE D 4 101 ? -72.195  41.568  -16.675 1.00 51.81  ? 237 PHE B CA  1 
ATOM 4511 C C   . PHE D 4 101 ? -71.252  42.727  -16.377 1.00 55.06  ? 237 PHE B C   1 
ATOM 4512 O O   . PHE D 4 101 ? -70.594  42.724  -15.331 1.00 61.84  ? 237 PHE B O   1 
ATOM 4513 C CB  . PHE D 4 101 ? -71.451  40.399  -17.328 1.00 38.86  ? 237 PHE B CB  1 
ATOM 4514 C CG  . PHE D 4 101 ? -72.129  39.067  -17.128 1.00 48.53  ? 237 PHE B CG  1 
ATOM 4515 C CD1 . PHE D 4 101 ? -72.615  38.703  -15.883 1.00 54.12  ? 237 PHE B CD1 1 
ATOM 4516 C CD2 . PHE D 4 101 ? -72.310  38.194  -18.190 1.00 52.96  ? 237 PHE B CD2 1 
ATOM 4517 C CE1 . PHE D 4 101 ? -73.248  37.485  -15.693 1.00 51.18  ? 237 PHE B CE1 1 
ATOM 4518 C CE2 . PHE D 4 101 ? -72.948  36.976  -18.007 1.00 46.74  ? 237 PHE B CE2 1 
ATOM 4519 C CZ  . PHE D 4 101 ? -73.414  36.622  -16.756 1.00 58.14  ? 237 PHE B CZ  1 
ATOM 4520 N N   . SER D 4 102 ? -71.198  43.733  -17.254 1.00 59.41  ? 238 SER B N   1 
ATOM 4521 C CA  . SER D 4 102 ? -70.345  44.892  -17.006 1.00 62.72  ? 238 SER B CA  1 
ATOM 4522 C C   . SER D 4 102 ? -70.845  45.714  -15.823 1.00 61.04  ? 238 SER B C   1 
ATOM 4523 O O   . SER D 4 102 ? -70.041  46.261  -15.059 1.00 59.44  ? 238 SER B O   1 
ATOM 4524 C CB  . SER D 4 102 ? -70.261  45.760  -18.260 1.00 52.35  ? 238 SER B CB  1 
ATOM 4525 O OG  . SER D 4 102 ? -69.404  45.172  -19.221 1.00 95.44  ? 238 SER B OG  1 
ATOM 4526 N N   . VAL D 4 103 ? -72.167  45.828  -15.659 1.00 50.18  ? 239 VAL B N   1 
ATOM 4527 C CA  . VAL D 4 103 ? -72.718  46.640  -14.577 1.00 52.40  ? 239 VAL B CA  1 
ATOM 4528 C C   . VAL D 4 103 ? -72.976  45.843  -13.307 1.00 59.04  ? 239 VAL B C   1 
ATOM 4529 O O   . VAL D 4 103 ? -73.345  46.436  -12.282 1.00 49.37  ? 239 VAL B O   1 
ATOM 4530 C CB  . VAL D 4 103 ? -74.028  47.331  -15.002 1.00 47.55  ? 239 VAL B CB  1 
ATOM 4531 C CG1 . VAL D 4 103 ? -73.728  48.574  -15.821 1.00 55.81  ? 239 VAL B CG1 1 
ATOM 4532 C CG2 . VAL D 4 103 ? -74.914  46.367  -15.773 1.00 46.63  ? 239 VAL B CG2 1 
ATOM 4533 N N   . ASN D 4 104 ? -72.796  44.522  -13.336 1.00 58.60  ? 240 ASN B N   1 
ATOM 4534 C CA  . ASN D 4 104 ? -73.056  43.676  -12.177 1.00 44.44  ? 240 ASN B CA  1 
ATOM 4535 C C   . ASN D 4 104 ? -71.842  42.850  -11.771 1.00 49.79  ? 240 ASN B C   1 
ATOM 4536 O O   . ASN D 4 104 ? -71.987  41.899  -10.994 1.00 53.91  ? 240 ASN B O   1 
ATOM 4537 C CB  . ASN D 4 104 ? -74.248  42.756  -12.449 1.00 45.53  ? 240 ASN B CB  1 
ATOM 4538 C CG  . ASN D 4 104 ? -75.559  43.509  -12.534 1.00 54.30  ? 240 ASN B CG  1 
ATOM 4539 O OD1 . ASN D 4 104 ? -75.969  43.945  -13.609 1.00 63.97  ? 240 ASN B OD1 1 
ATOM 4540 N ND2 . ASN D 4 104 ? -76.224  43.669  -11.396 1.00 66.81  ? 240 ASN B ND2 1 
ATOM 4541 N N   . ALA D 4 105 ? -70.656  43.182  -12.284 1.00 51.63  ? 241 ALA B N   1 
ATOM 4542 C CA  . ALA D 4 105 ? -69.402  42.538  -11.884 1.00 42.17  ? 241 ALA B CA  1 
ATOM 4543 C C   . ALA D 4 105 ? -69.456  41.021  -12.059 1.00 48.80  ? 241 ALA B C   1 
ATOM 4544 O O   . ALA D 4 105 ? -68.955  40.265  -11.225 1.00 58.08  ? 241 ALA B O   1 
ATOM 4545 C CB  . ALA D 4 105 ? -69.029  42.904  -10.446 1.00 48.00  ? 241 ALA B CB  1 
ATOM 4546 N N   . GLY D 4 106 ? -70.074  40.570  -13.148 1.00 42.71  ? 242 GLY B N   1 
ATOM 4547 C CA  . GLY D 4 106 ? -70.056  39.167  -13.504 1.00 47.11  ? 242 GLY B CA  1 
ATOM 4548 C C   . GLY D 4 106 ? -71.064  38.285  -12.798 1.00 47.32  ? 242 GLY B C   1 
ATOM 4549 O O   . GLY D 4 106 ? -71.079  37.073  -13.050 1.00 48.64  ? 242 GLY B O   1 
ATOM 4550 N N   . VAL D 4 107 ? -71.893  38.833  -11.912 1.00 39.27  ? 243 VAL B N   1 
ATOM 4551 C CA  . VAL D 4 107 ? -72.930  38.066  -11.229 1.00 40.16  ? 243 VAL B CA  1 
ATOM 4552 C C   . VAL D 4 107 ? -74.231  38.849  -11.325 1.00 42.87  ? 243 VAL B C   1 
ATOM 4553 O O   . VAL D 4 107 ? -74.285  40.017  -10.922 1.00 53.67  ? 243 VAL B O   1 
ATOM 4554 C CB  . VAL D 4 107 ? -72.577  37.785  -9.759  1.00 36.08  ? 243 VAL B CB  1 
ATOM 4555 C CG1 . VAL D 4 107 ? -73.698  37.005  -9.093  1.00 38.67  ? 243 VAL B CG1 1 
ATOM 4556 C CG2 . VAL D 4 107 ? -71.258  37.033  -9.656  1.00 43.80  ? 243 VAL B CG2 1 
ATOM 4557 N N   . THR D 4 108 ? -75.277  38.212  -11.846 1.00 43.52  ? 244 THR B N   1 
ATOM 4558 C CA  . THR D 4 108 ? -76.561  38.868  -12.044 1.00 47.32  ? 244 THR B CA  1 
ATOM 4559 C C   . THR D 4 108 ? -77.670  38.052  -11.398 1.00 48.10  ? 244 THR B C   1 
ATOM 4560 O O   . THR D 4 108 ? -77.586  36.825  -11.295 1.00 49.07  ? 244 THR B O   1 
ATOM 4561 C CB  . THR D 4 108 ? -76.877  39.077  -13.541 1.00 61.41  ? 244 THR B CB  1 
ATOM 4562 O OG1 . THR D 4 108 ? -77.127  37.812  -14.169 1.00 51.46  ? 244 THR B OG1 1 
ATOM 4563 C CG2 . THR D 4 108 ? -75.721  39.777  -14.249 1.00 57.68  ? 244 THR B CG2 1 
ATOM 4564 N N   . THR D 4 109 ? -78.707  38.757  -10.951 1.00 50.87  ? 245 THR B N   1 
ATOM 4565 C CA  . THR D 4 109 ? -79.910  38.156  -10.392 1.00 47.38  ? 245 THR B CA  1 
ATOM 4566 C C   . THR D 4 109 ? -81.014  39.208  -10.374 1.00 44.20  ? 245 THR B C   1 
ATOM 4567 O O   . THR D 4 109 ? -80.797  40.323  -9.885  1.00 61.48  ? 245 THR B O   1 
ATOM 4568 C CB  . THR D 4 109 ? -79.654  37.601  -8.987  1.00 54.30  ? 245 THR B CB  1 
ATOM 4569 O OG1 . THR D 4 109 ? -80.902  37.275  -8.361  1.00 55.70  ? 245 THR B OG1 1 
ATOM 4570 C CG2 . THR D 4 109 ? -78.902  38.614  -8.128  1.00 55.10  ? 245 THR B CG2 1 
ATOM 4571 N N   . PRO D 4 110 ? -82.201  38.911  -10.913 1.00 42.68  ? 246 PRO B N   1 
ATOM 4572 C CA  . PRO D 4 110 ? -82.639  37.648  -11.530 1.00 52.49  ? 246 PRO B CA  1 
ATOM 4573 C C   . PRO D 4 110 ? -81.975  37.367  -12.868 1.00 52.58  ? 246 PRO B C   1 
ATOM 4574 O O   . PRO D 4 110 ? -81.434  38.264  -13.509 1.00 61.79  ? 246 PRO B O   1 
ATOM 4575 C CB  . PRO D 4 110 ? -84.151  37.857  -11.711 1.00 49.52  ? 246 PRO B CB  1 
ATOM 4576 C CG  . PRO D 4 110 ? -84.309  39.339  -11.844 1.00 48.76  ? 246 PRO B CG  1 
ATOM 4577 C CD  . PRO D 4 110 ? -83.275  39.920  -10.917 1.00 53.29  ? 246 PRO B CD  1 
ATOM 4578 N N   . VAL D 4 111 ? -82.007  36.110  -13.303 1.00 51.03  ? 247 VAL B N   1 
ATOM 4579 C CA  . VAL D 4 111 ? -81.472  35.750  -14.609 1.00 43.83  ? 247 VAL B CA  1 
ATOM 4580 C C   . VAL D 4 111 ? -82.375  36.342  -15.684 1.00 53.58  ? 247 VAL B C   1 
ATOM 4581 O O   . VAL D 4 111 ? -83.560  36.001  -15.780 1.00 49.18  ? 247 VAL B O   1 
ATOM 4582 C CB  . VAL D 4 111 ? -81.352  34.228  -14.747 1.00 41.59  ? 247 VAL B CB  1 
ATOM 4583 C CG1 . VAL D 4 111 ? -80.914  33.852  -16.155 1.00 51.14  ? 247 VAL B CG1 1 
ATOM 4584 C CG2 . VAL D 4 111 ? -80.372  33.690  -13.721 1.00 42.52  ? 247 VAL B CG2 1 
ATOM 4585 N N   . SER D 4 112 ? -81.820  37.246  -16.488 1.00 50.56  ? 248 SER B N   1 
ATOM 4586 C CA  . SER D 4 112 ? -82.606  37.936  -17.496 1.00 47.71  ? 248 SER B CA  1 
ATOM 4587 C C   . SER D 4 112 ? -82.943  36.994  -18.647 1.00 50.42  ? 248 SER B C   1 
ATOM 4588 O O   . SER D 4 112 ? -82.424  35.879  -18.753 1.00 50.16  ? 248 SER B O   1 
ATOM 4589 C CB  . SER D 4 112 ? -81.855  39.160  -18.015 1.00 56.32  ? 248 SER B CB  1 
ATOM 4590 O OG  . SER D 4 112 ? -80.635  38.782  -18.628 1.00 54.14  ? 248 SER B OG  1 
ATOM 4591 N N   . THR D 4 113 ? -83.844  37.456  -19.518 1.00 59.25  ? 249 THR B N   1 
ATOM 4592 C CA  . THR D 4 113 ? -84.197  36.666  -20.693 1.00 61.20  ? 249 THR B CA  1 
ATOM 4593 C C   . THR D 4 113 ? -83.052  36.606  -21.696 1.00 47.86  ? 249 THR B C   1 
ATOM 4594 O O   . THR D 4 113 ? -82.958  35.643  -22.463 1.00 55.51  ? 249 THR B O   1 
ATOM 4595 C CB  . THR D 4 113 ? -85.457  37.227  -21.353 1.00 66.59  ? 249 THR B CB  1 
ATOM 4596 O OG1 . THR D 4 113 ? -85.238  38.593  -21.724 1.00 80.01  ? 249 THR B OG1 1 
ATOM 4597 C CG2 . THR D 4 113 ? -86.641  37.142  -20.397 1.00 53.78  ? 249 THR B CG2 1 
ATOM 4598 N N   . TYR D 4 114 ? -82.186  37.625  -21.719 1.00 44.10  ? 250 TYR B N   1 
ATOM 4599 C CA  . TYR D 4 114 ? -80.985  37.552  -22.547 1.00 46.98  ? 250 TYR B CA  1 
ATOM 4600 C C   . TYR D 4 114 ? -80.052  36.454  -22.058 1.00 50.97  ? 250 TYR B C   1 
ATOM 4601 O O   . TYR D 4 114 ? -79.425  35.751  -22.862 1.00 45.08  ? 250 TYR B O   1 
ATOM 4602 C CB  . TYR D 4 114 ? -80.254  38.895  -22.550 1.00 42.30  ? 250 TYR B CB  1 
ATOM 4603 C CG  . TYR D 4 114 ? -81.038  40.046  -23.129 1.00 48.02  ? 250 TYR B CG  1 
ATOM 4604 C CD1 . TYR D 4 114 ? -81.366  40.082  -24.477 1.00 61.23  ? 250 TYR B CD1 1 
ATOM 4605 C CD2 . TYR D 4 114 ? -81.444  41.101  -22.328 1.00 68.98  ? 250 TYR B CD2 1 
ATOM 4606 C CE1 . TYR D 4 114 ? -82.079  41.141  -25.009 1.00 72.66  ? 250 TYR B CE1 1 
ATOM 4607 C CE2 . TYR D 4 114 ? -82.159  42.159  -22.849 1.00 76.73  ? 250 TYR B CE2 1 
ATOM 4608 C CZ  . TYR D 4 114 ? -82.472  42.176  -24.187 1.00 61.52  ? 250 TYR B CZ  1 
ATOM 4609 O OH  . TYR D 4 114 ? -83.183  43.236  -24.701 1.00 88.74  ? 250 TYR B OH  1 
ATOM 4610 N N   . MET D 4 115 ? -79.928  36.310  -20.738 1.00 55.30  ? 251 MET B N   1 
ATOM 4611 C CA  . MET D 4 115 ? -79.079  35.267  -20.175 1.00 50.41  ? 251 MET B CA  1 
ATOM 4612 C C   . MET D 4 115 ? -79.667  33.882  -20.422 1.00 46.46  ? 251 MET B C   1 
ATOM 4613 O O   . MET D 4 115 ? -78.930  32.926  -20.690 1.00 44.97  ? 251 MET B O   1 
ATOM 4614 C CB  . MET D 4 115 ? -78.885  35.518  -18.682 1.00 36.89  ? 251 MET B CB  1 
ATOM 4615 C CG  . MET D 4 115 ? -77.473  35.288  -18.197 1.00 57.70  ? 251 MET B CG  1 
ATOM 4616 S SD  . MET D 4 115 ? -76.359  36.631  -18.642 1.00 49.57  ? 251 MET B SD  1 
ATOM 4617 C CE  . MET D 4 115 ? -77.078  37.997  -17.738 1.00 56.74  ? 251 MET B CE  1 
ATOM 4618 N N   . LEU D 4 116 ? -80.989  33.755  -20.334 1.00 52.99  ? 252 LEU B N   1 
ATOM 4619 C CA  . LEU D 4 116 ? -81.663  32.480  -20.562 1.00 47.19  ? 252 LEU B CA  1 
ATOM 4620 C C   . LEU D 4 116 ? -83.094  32.781  -20.983 1.00 45.97  ? 252 LEU B C   1 
ATOM 4621 O O   . LEU D 4 116 ? -83.874  33.317  -20.192 1.00 52.98  ? 252 LEU B O   1 
ATOM 4622 C CB  . LEU D 4 116 ? -81.631  31.608  -19.311 1.00 46.25  ? 252 LEU B CB  1 
ATOM 4623 C CG  . LEU D 4 116 ? -81.526  30.097  -19.527 1.00 47.19  ? 252 LEU B CG  1 
ATOM 4624 C CD1 . LEU D 4 116 ? -80.240  29.746  -20.251 1.00 58.46  ? 252 LEU B CD1 1 
ATOM 4625 C CD2 . LEU D 4 116 ? -81.614  29.361  -18.197 1.00 54.04  ? 252 LEU B CD2 1 
ATOM 4626 N N   . THR D 4 117 ? -83.436  32.447  -22.221 1.00 50.25  ? 253 THR B N   1 
ATOM 4627 C CA  . THR D 4 117 ? -84.785  32.687  -22.697 1.00 54.03  ? 253 THR B CA  1 
ATOM 4628 C C   . THR D 4 117 ? -85.752  31.704  -22.041 1.00 49.59  ? 253 THR B C   1 
ATOM 4629 O O   . THR D 4 117 ? -85.353  30.732  -21.394 1.00 55.19  ? 253 THR B O   1 
ATOM 4630 C CB  . THR D 4 117 ? -84.845  32.573  -24.220 1.00 46.29  ? 253 THR B CB  1 
ATOM 4631 O OG1 . THR D 4 117 ? -84.784  31.193  -24.601 1.00 47.62  ? 253 THR B OG1 1 
ATOM 4632 C CG2 . THR D 4 117 ? -83.668  33.307  -24.841 1.00 38.15  ? 253 THR B CG2 1 
ATOM 4633 N N   . ASN D 4 118 ? -87.048  31.978  -22.206 1.00 53.96  ? 254 ASN B N   1 
ATOM 4634 C CA  . ASN D 4 118 ? -88.064  31.129  -21.592 1.00 48.34  ? 254 ASN B CA  1 
ATOM 4635 C C   . ASN D 4 118 ? -88.004  29.708  -22.132 1.00 54.57  ? 254 ASN B C   1 
ATOM 4636 O O   . ASN D 4 118 ? -88.127  28.742  -21.368 1.00 59.92  ? 254 ASN B O   1 
ATOM 4637 C CB  . ASN D 4 118 ? -89.452  31.720  -21.816 1.00 47.31  ? 254 ASN B CB  1 
ATOM 4638 C CG  . ASN D 4 118 ? -90.087  32.195  -20.539 1.00 62.02  ? 254 ASN B CG  1 
ATOM 4639 O OD1 . ASN D 4 118 ? -89.396  32.505  -19.569 1.00 78.66  ? 254 ASN B OD1 1 
ATOM 4640 N ND2 . ASN D 4 118 ? -91.413  32.247  -20.523 1.00 89.04  ? 254 ASN B ND2 1 
ATOM 4641 N N   . SER D 4 119 ? -87.827  29.559  -23.448 1.00 54.34  ? 255 SER B N   1 
ATOM 4642 C CA  . SER D 4 119 ? -87.773  28.224  -24.034 1.00 48.93  ? 255 SER B CA  1 
ATOM 4643 C C   . SER D 4 119 ? -86.551  27.460  -23.542 1.00 53.80  ? 255 SER B C   1 
ATOM 4644 O O   . SER D 4 119 ? -86.635  26.261  -23.248 1.00 63.23  ? 255 SER B O   1 
ATOM 4645 C CB  . SER D 4 119 ? -87.773  28.313  -25.559 1.00 53.02  ? 255 SER B CB  1 
ATOM 4646 O OG  . SER D 4 119 ? -86.668  29.064  -26.029 1.00 82.38  ? 255 SER B OG  1 
ATOM 4647 N N   . GLU D 4 120 ? -85.404  28.136  -23.450 1.00 41.55  ? 256 GLU B N   1 
ATOM 4648 C CA  . GLU D 4 120 ? -84.205  27.478  -22.945 1.00 47.29  ? 256 GLU B CA  1 
ATOM 4649 C C   . GLU D 4 120 ? -84.366  27.099  -21.477 1.00 56.05  ? 256 GLU B C   1 
ATOM 4650 O O   . GLU D 4 120 ? -83.987  25.995  -21.071 1.00 61.66  ? 256 GLU B O   1 
ATOM 4651 C CB  . GLU D 4 120 ? -82.986  28.380  -23.144 1.00 43.40  ? 256 GLU B CB  1 
ATOM 4652 C CG  . GLU D 4 120 ? -82.683  28.699  -24.597 1.00 56.04  ? 256 GLU B CG  1 
ATOM 4653 C CD  . GLU D 4 120 ? -81.907  29.992  -24.769 1.00 60.30  ? 256 GLU B CD  1 
ATOM 4654 O OE1 . GLU D 4 120 ? -81.862  30.792  -23.812 1.00 60.86  ? 256 GLU B OE1 1 
ATOM 4655 O OE2 . GLU D 4 120 ? -81.353  30.215  -25.869 1.00 62.33  ? 256 GLU B OE2 1 
ATOM 4656 N N   . LEU D 4 121 ? -84.935  28.000  -20.669 1.00 50.83  ? 257 LEU B N   1 
ATOM 4657 C CA  . LEU D 4 121 ? -85.133  27.705  -19.253 1.00 44.97  ? 257 LEU B CA  1 
ATOM 4658 C C   . LEU D 4 121 ? -86.122  26.563  -19.057 1.00 55.08  ? 257 LEU B C   1 
ATOM 4659 O O   . LEU D 4 121 ? -85.915  25.697  -18.197 1.00 54.74  ? 257 LEU B O   1 
ATOM 4660 C CB  . LEU D 4 121 ? -85.601  28.959  -18.511 1.00 51.31  ? 257 LEU B CB  1 
ATOM 4661 C CG  . LEU D 4 121 ? -85.926  28.774  -17.021 1.00 47.62  ? 257 LEU B CG  1 
ATOM 4662 C CD1 . LEU D 4 121 ? -84.727  28.228  -16.266 1.00 41.58  ? 257 LEU B CD1 1 
ATOM 4663 C CD2 . LEU D 4 121 ? -86.408  30.075  -16.397 1.00 42.42  ? 257 LEU B CD2 1 
ATOM 4664 N N   . LEU D 4 122 ? -87.207  26.546  -19.837 1.00 41.11  ? 258 LEU B N   1 
ATOM 4665 C CA  . LEU D 4 122 ? -88.165  25.450  -19.734 1.00 43.09  ? 258 LEU B CA  1 
ATOM 4666 C C   . LEU D 4 122 ? -87.538  24.127  -20.153 1.00 52.66  ? 258 LEU B C   1 
ATOM 4667 O O   . LEU D 4 122 ? -87.790  23.087  -19.532 1.00 54.56  ? 258 LEU B O   1 
ATOM 4668 C CB  . LEU D 4 122 ? -89.399  25.748  -20.580 1.00 31.46  ? 258 LEU B CB  1 
ATOM 4669 C CG  . LEU D 4 122 ? -90.379  26.730  -19.948 1.00 30.61  ? 258 LEU B CG  1 
ATOM 4670 C CD1 . LEU D 4 122 ? -91.492  27.071  -20.906 1.00 31.64  ? 258 LEU B CD1 1 
ATOM 4671 C CD2 . LEU D 4 122 ? -90.925  26.155  -18.645 1.00 57.61  ? 258 LEU B CD2 1 
ATOM 4672 N N   . SER D 4 123 ? -86.731  24.144  -21.218 1.00 55.48  ? 259 SER B N   1 
ATOM 4673 C CA  . SER D 4 123 ? -86.010  22.941  -21.621 1.00 53.12  ? 259 SER B CA  1 
ATOM 4674 C C   . SER D 4 123 ? -85.030  22.504  -20.542 1.00 52.60  ? 259 SER B C   1 
ATOM 4675 O O   . SER D 4 123 ? -84.899  21.308  -20.255 1.00 53.62  ? 259 SER B O   1 
ATOM 4676 C CB  . SER D 4 123 ? -85.277  23.186  -22.939 1.00 45.11  ? 259 SER B CB  1 
ATOM 4677 O OG  . SER D 4 123 ? -84.674  21.994  -23.411 1.00 63.41  ? 259 SER B OG  1 
ATOM 4678 N N   . LEU D 4 124 ? -84.335  23.465  -19.932 1.00 55.71  ? 260 LEU B N   1 
ATOM 4679 C CA  . LEU D 4 124 ? -83.430  23.150  -18.834 1.00 54.58  ? 260 LEU B CA  1 
ATOM 4680 C C   . LEU D 4 124 ? -84.180  22.500  -17.678 1.00 52.72  ? 260 LEU B C   1 
ATOM 4681 O O   . LEU D 4 124 ? -83.723  21.498  -17.118 1.00 48.32  ? 260 LEU B O   1 
ATOM 4682 C CB  . LEU D 4 124 ? -82.722  24.426  -18.378 1.00 53.75  ? 260 LEU B CB  1 
ATOM 4683 C CG  . LEU D 4 124 ? -81.494  24.311  -17.480 1.00 59.00  ? 260 LEU B CG  1 
ATOM 4684 C CD1 . LEU D 4 124 ? -80.668  23.103  -17.864 1.00 76.97  ? 260 LEU B CD1 1 
ATOM 4685 C CD2 . LEU D 4 124 ? -80.669  25.578  -17.606 1.00 43.75  ? 260 LEU B CD2 1 
ATOM 4686 N N   . ILE D 4 125 ? -85.351  23.042  -17.332 1.00 51.38  ? 261 ILE B N   1 
ATOM 4687 C CA  . ILE D 4 125 ? -86.162  22.469  -16.260 1.00 47.84  ? 261 ILE B CA  1 
ATOM 4688 C C   . ILE D 4 125 ? -86.589  21.051  -16.614 1.00 53.42  ? 261 ILE B C   1 
ATOM 4689 O O   . ILE D 4 125 ? -86.595  20.156  -15.759 1.00 56.54  ? 261 ILE B O   1 
ATOM 4690 C CB  . ILE D 4 125 ? -87.378  23.370  -15.975 1.00 43.02  ? 261 ILE B CB  1 
ATOM 4691 C CG1 . ILE D 4 125 ? -86.936  24.687  -15.338 1.00 43.97  ? 261 ILE B CG1 1 
ATOM 4692 C CG2 . ILE D 4 125 ? -88.382  22.663  -15.078 1.00 37.85  ? 261 ILE B CG2 1 
ATOM 4693 C CD1 . ILE D 4 125 ? -88.061  25.679  -15.170 1.00 42.83  ? 261 ILE B CD1 1 
ATOM 4694 N N   . ASN D 4 126 ? -86.948  20.822  -17.881 1.00 58.82  ? 262 ASN B N   1 
ATOM 4695 C CA  . ASN D 4 126 ? -87.450  19.511  -18.284 1.00 64.20  ? 262 ASN B CA  1 
ATOM 4696 C C   . ASN D 4 126 ? -86.392  18.428  -18.103 1.00 64.52  ? 262 ASN B C   1 
ATOM 4697 O O   . ASN D 4 126 ? -86.718  17.281  -17.774 1.00 70.26  ? 262 ASN B O   1 
ATOM 4698 C CB  . ASN D 4 126 ? -87.929  19.557  -19.734 1.00 57.79  ? 262 ASN B CB  1 
ATOM 4699 C CG  . ASN D 4 126 ? -88.987  18.509  -20.037 1.00 65.47  ? 262 ASN B CG  1 
ATOM 4700 O OD1 . ASN D 4 126 ? -89.799  18.679  -20.947 1.00 85.38  ? 262 ASN B OD1 1 
ATOM 4701 N ND2 . ASN D 4 126 ? -88.988  17.423  -19.272 1.00 63.85  ? 262 ASN B ND2 1 
ATOM 4702 N N   . ASP D 4 127 ? -85.124  18.765  -18.319 1.00 68.77  ? 263 ASP B N   1 
ATOM 4703 C CA  . ASP D 4 127 ? -84.045  17.789  -18.260 1.00 69.89  ? 263 ASP B CA  1 
ATOM 4704 C C   . ASP D 4 127 ? -83.313  17.777  -16.923 1.00 59.59  ? 263 ASP B C   1 
ATOM 4705 O O   . ASP D 4 127 ? -82.354  17.015  -16.769 1.00 69.38  ? 263 ASP B O   1 
ATOM 4706 C CB  . ASP D 4 127 ? -83.052  18.039  -19.399 1.00 71.48  ? 263 ASP B CB  1 
ATOM 4707 C CG  . ASP D 4 127 ? -83.586  17.583  -20.745 1.00 74.22  ? 263 ASP B CG  1 
ATOM 4708 O OD1 . ASP D 4 127 ? -83.859  16.374  -20.902 1.00 76.77  ? 263 ASP B OD1 1 
ATOM 4709 O OD2 . ASP D 4 127 ? -83.746  18.436  -21.642 1.00 73.90  ? 263 ASP B OD2 1 
ATOM 4710 N N   . MET D 4 128 ? -83.734  18.591  -15.958 1.00 68.69  ? 264 MET B N   1 
ATOM 4711 C CA  . MET D 4 128 ? -83.113  18.560  -14.643 1.00 65.22  ? 264 MET B CA  1 
ATOM 4712 C C   . MET D 4 128 ? -83.462  17.258  -13.922 1.00 55.60  ? 264 MET B C   1 
ATOM 4713 O O   . MET D 4 128 ? -84.564  16.727  -14.079 1.00 69.59  ? 264 MET B O   1 
ATOM 4714 C CB  . MET D 4 128 ? -83.564  19.752  -13.803 1.00 52.59  ? 264 MET B CB  1 
ATOM 4715 C CG  . MET D 4 128 ? -82.790  21.026  -14.083 1.00 51.39  ? 264 MET B CG  1 
ATOM 4716 S SD  . MET D 4 128 ? -83.320  22.440  -13.098 1.00 63.44  ? 264 MET B SD  1 
ATOM 4717 C CE  . MET D 4 128 ? -83.679  21.675  -11.520 1.00 66.21  ? 264 MET B CE  1 
ATOM 4718 N N   . PRO D 4 129 ? -82.542  16.727  -13.116 1.00 65.73  ? 265 PRO B N   1 
ATOM 4719 C CA  . PRO D 4 129 ? -82.816  15.458  -12.406 1.00 70.00  ? 265 PRO B CA  1 
ATOM 4720 C C   . PRO D 4 129 ? -83.676  15.668  -11.166 1.00 58.41  ? 265 PRO B C   1 
ATOM 4721 O O   . PRO D 4 129 ? -83.234  15.542  -10.020 1.00 66.49  ? 265 PRO B O   1 
ATOM 4722 C CB  . PRO D 4 129 ? -81.405  14.964  -12.072 1.00 67.82  ? 265 PRO B CB  1 
ATOM 4723 C CG  . PRO D 4 129 ? -80.623  16.222  -11.867 1.00 57.90  ? 265 PRO B CG  1 
ATOM 4724 C CD  . PRO D 4 129 ? -81.188  17.237  -12.836 1.00 76.46  ? 265 PRO B CD  1 
ATOM 4725 N N   . ILE D 4 130 ? -84.949  15.997  -11.388 1.00 62.13  ? 266 ILE B N   1 
ATOM 4726 C CA  . ILE D 4 130 ? -85.877  16.303  -10.309 1.00 69.30  ? 266 ILE B CA  1 
ATOM 4727 C C   . ILE D 4 130 ? -87.194  15.578  -10.565 1.00 59.07  ? 266 ILE B C   1 
ATOM 4728 O O   . ILE D 4 130 ? -87.424  15.009  -11.633 1.00 61.03  ? 266 ILE B O   1 
ATOM 4729 C CB  . ILE D 4 130 ? -86.123  17.818  -10.156 1.00 62.18  ? 266 ILE B CB  1 
ATOM 4730 C CG1 . ILE D 4 130 ? -86.489  18.437  -11.504 1.00 66.65  ? 266 ILE B CG1 1 
ATOM 4731 C CG2 . ILE D 4 130 ? -84.891  18.502  -9.587  1.00 61.29  ? 266 ILE B CG2 1 
ATOM 4732 C CD1 . ILE D 4 130 ? -86.830  19.906  -11.428 1.00 63.37  ? 266 ILE B CD1 1 
ATOM 4733 N N   . THR D 4 131 ? -88.063  15.615  -9.559  1.00 63.97  ? 267 THR B N   1 
ATOM 4734 C CA  . THR D 4 131 ? -89.365  14.970  -9.650  1.00 67.79  ? 267 THR B CA  1 
ATOM 4735 C C   . THR D 4 131 ? -90.245  15.689  -10.667 1.00 70.20  ? 267 THR B C   1 
ATOM 4736 O O   . THR D 4 131 ? -90.076  16.882  -10.933 1.00 86.11  ? 267 THR B O   1 
ATOM 4737 C CB  . THR D 4 131 ? -90.044  14.966  -8.278  1.00 77.37  ? 267 THR B CB  1 
ATOM 4738 O OG1 . THR D 4 131 ? -89.083  14.621  -7.274  1.00 72.04  ? 267 THR B OG1 1 
ATOM 4739 C CG2 . THR D 4 131 ? -91.177  13.947  -8.235  1.00 87.97  ? 267 THR B CG2 1 
ATOM 4740 N N   . ASN D 4 132 ? -91.188  14.944  -11.253 1.00 73.88  ? 268 ASN B N   1 
ATOM 4741 C CA  . ASN D 4 132 ? -92.162  15.565  -12.147 1.00 76.77  ? 268 ASN B CA  1 
ATOM 4742 C C   . ASN D 4 132 ? -92.996  16.611  -11.422 1.00 74.61  ? 268 ASN B C   1 
ATOM 4743 O O   . ASN D 4 132 ? -93.458  17.575  -12.043 1.00 76.43  ? 268 ASN B O   1 
ATOM 4744 C CB  . ASN D 4 132 ? -93.069  14.503  -12.768 1.00 74.33  ? 268 ASN B CB  1 
ATOM 4745 C CG  . ASN D 4 132 ? -92.345  13.638  -13.776 1.00 79.02  ? 268 ASN B CG  1 
ATOM 4746 O OD1 . ASN D 4 132 ? -91.356  12.981  -13.454 1.00 100.37 ? 268 ASN B OD1 1 
ATOM 4747 N ND2 . ASN D 4 132 ? -92.835  13.635  -15.009 1.00 99.10  ? 268 ASN B ND2 1 
ATOM 4748 N N   . ASP D 4 133 ? -93.207  16.436  -10.116 1.00 72.32  ? 269 ASP B N   1 
ATOM 4749 C CA  . ASP D 4 133 ? -93.862  17.475  -9.330  1.00 74.92  ? 269 ASP B CA  1 
ATOM 4750 C C   . ASP D 4 133 ? -93.033  18.753  -9.321  1.00 75.03  ? 269 ASP B C   1 
ATOM 4751 O O   . ASP D 4 133 ? -93.572  19.856  -9.466  1.00 79.55  ? 269 ASP B O   1 
ATOM 4752 C CB  . ASP D 4 133 ? -94.097  16.985  -7.901  1.00 84.69  ? 269 ASP B CB  1 
ATOM 4753 C CG  . ASP D 4 133 ? -95.023  15.787  -7.839  1.00 100.01 ? 269 ASP B CG  1 
ATOM 4754 O OD1 . ASP D 4 133 ? -96.255  15.987  -7.781  1.00 102.91 ? 269 ASP B OD1 1 
ATOM 4755 O OD2 . ASP D 4 133 ? -94.516  14.645  -7.842  1.00 107.00 ? 269 ASP B OD2 1 
ATOM 4756 N N   . GLN D 4 134 ? -91.715  18.621  -9.151  1.00 69.91  ? 270 GLN B N   1 
ATOM 4757 C CA  . GLN D 4 134 ? -90.852  19.797  -9.130  1.00 66.42  ? 270 GLN B CA  1 
ATOM 4758 C C   . GLN D 4 134 ? -90.726  20.417  -10.516 1.00 64.73  ? 270 GLN B C   1 
ATOM 4759 O O   . GLN D 4 134 ? -90.666  21.645  -10.649 1.00 69.07  ? 270 GLN B O   1 
ATOM 4760 C CB  . GLN D 4 134 ? -89.480  19.432  -8.563  1.00 69.95  ? 270 GLN B CB  1 
ATOM 4761 C CG  . GLN D 4 134 ? -89.541  18.908  -7.136  1.00 74.54  ? 270 GLN B CG  1 
ATOM 4762 C CD  . GLN D 4 134 ? -88.178  18.579  -6.556  1.00 68.57  ? 270 GLN B CD  1 
ATOM 4763 O OE1 . GLN D 4 134 ? -87.159  18.675  -7.236  1.00 71.80  ? 270 GLN B OE1 1 
ATOM 4764 N NE2 . GLN D 4 134 ? -88.155  18.200  -5.284  1.00 88.79  ? 270 GLN B NE2 1 
ATOM 4765 N N   . LYS D 4 135 ? -90.686  19.586  -11.562 1.00 77.86  ? 271 LYS B N   1 
ATOM 4766 C CA  . LYS D 4 135 ? -90.675  20.118  -12.921 1.00 55.13  ? 271 LYS B CA  1 
ATOM 4767 C C   . LYS D 4 135 ? -91.947  20.900  -13.212 1.00 49.54  ? 271 LYS B C   1 
ATOM 4768 O O   . LYS D 4 135 ? -91.898  21.980  -13.813 1.00 57.45  ? 271 LYS B O   1 
ATOM 4769 C CB  . LYS D 4 135 ? -90.504  18.983  -13.930 1.00 52.45  ? 271 LYS B CB  1 
ATOM 4770 C CG  . LYS D 4 135 ? -89.139  18.328  -13.895 1.00 64.39  ? 271 LYS B CG  1 
ATOM 4771 C CD  . LYS D 4 135 ? -89.010  17.239  -14.945 1.00 65.13  ? 271 LYS B CD  1 
ATOM 4772 C CE  . LYS D 4 135 ? -87.689  16.503  -14.804 1.00 62.41  ? 271 LYS B CE  1 
ATOM 4773 N NZ  . LYS D 4 135 ? -87.565  15.382  -15.773 1.00 81.15  ? 271 LYS B NZ  1 
ATOM 4774 N N   . LYS D 4 136 ? -93.098  20.371  -12.792 1.00 51.18  ? 272 LYS B N   1 
ATOM 4775 C CA  . LYS D 4 136 ? -94.358  21.072  -13.010 1.00 54.78  ? 272 LYS B CA  1 
ATOM 4776 C C   . LYS D 4 136 ? -94.387  22.393  -12.253 1.00 50.67  ? 272 LYS B C   1 
ATOM 4777 O O   . LYS D 4 136 ? -94.860  23.410  -12.776 1.00 49.26  ? 272 LYS B O   1 
ATOM 4778 C CB  . LYS D 4 136 ? -95.528  20.181  -12.594 1.00 52.30  ? 272 LYS B CB  1 
ATOM 4779 C CG  . LYS D 4 136 ? -96.876  20.877  -12.593 1.00 61.46  ? 272 LYS B CG  1 
ATOM 4780 C CD  . LYS D 4 136 ? -97.987  19.916  -12.207 1.00 82.17  ? 272 LYS B CD  1 
ATOM 4781 C CE  . LYS D 4 136 ? -99.098  20.627  -11.450 1.00 101.22 ? 272 LYS B CE  1 
ATOM 4782 N NZ  . LYS D 4 136 ? -100.403 19.924  -11.598 1.00 104.70 ? 272 LYS B NZ  1 
ATOM 4783 N N   . LEU D 4 137 ? -93.880  22.397  -11.020 1.00 63.53  ? 273 LEU B N   1 
ATOM 4784 C CA  . LEU D 4 137 ? -93.887  23.611  -10.212 1.00 54.75  ? 273 LEU B CA  1 
ATOM 4785 C C   . LEU D 4 137 ? -92.996  24.692  -10.816 1.00 54.39  ? 273 LEU B C   1 
ATOM 4786 O O   . LEU D 4 137 ? -93.392  25.861  -10.897 1.00 51.32  ? 273 LEU B O   1 
ATOM 4787 C CB  . LEU D 4 137 ? -93.451  23.282  -8.786  1.00 45.59  ? 273 LEU B CB  1 
ATOM 4788 C CG  . LEU D 4 137 ? -93.270  24.502  -7.892  1.00 59.07  ? 273 LEU B CG  1 
ATOM 4789 C CD1 . LEU D 4 137 ? -94.601  25.197  -7.720  1.00 63.08  ? 273 LEU B CD1 1 
ATOM 4790 C CD2 . LEU D 4 137 ? -92.700  24.094  -6.549  1.00 48.83  ? 273 LEU B CD2 1 
ATOM 4791 N N   . MET D 4 138 ? -91.786  24.322  -11.244 1.00 49.58  ? 274 MET B N   1 
ATOM 4792 C CA  . MET D 4 138 ? -90.868  25.307  -11.809 1.00 42.45  ? 274 MET B CA  1 
ATOM 4793 C C   . MET D 4 138 ? -91.387  25.850  -13.135 1.00 52.11  ? 274 MET B C   1 
ATOM 4794 O O   . MET D 4 138 ? -91.239  27.044  -13.427 1.00 50.62  ? 274 MET B O   1 
ATOM 4795 C CB  . MET D 4 138 ? -89.487  24.687  -11.996 1.00 37.92  ? 274 MET B CB  1 
ATOM 4796 C CG  . MET D 4 138 ? -88.813  24.263  -10.717 1.00 42.59  ? 274 MET B CG  1 
ATOM 4797 S SD  . MET D 4 138 ? -87.143  23.659  -11.008 1.00 57.20  ? 274 MET B SD  1 
ATOM 4798 C CE  . MET D 4 138 ? -86.359  25.153  -11.607 1.00 54.59  ? 274 MET B CE  1 
ATOM 4799 N N   . SER D 4 139 ? -91.984  24.982  -13.956 1.00 50.21  ? 275 SER B N   1 
ATOM 4800 C CA  . SER D 4 139 ? -92.503  25.406  -15.252 1.00 48.08  ? 275 SER B CA  1 
ATOM 4801 C C   . SER D 4 139 ? -93.669  26.375  -15.096 1.00 52.66  ? 275 SER B C   1 
ATOM 4802 O O   . SER D 4 139 ? -93.799  27.330  -15.871 1.00 58.64  ? 275 SER B O   1 
ATOM 4803 C CB  . SER D 4 139 ? -92.924  24.184  -16.063 1.00 51.96  ? 275 SER B CB  1 
ATOM 4804 O OG  . SER D 4 139 ? -91.837  23.291  -16.233 1.00 56.46  ? 275 SER B OG  1 
ATOM 4805 N N   . ASN D 4 140 ? -94.534  26.140  -14.105 1.00 54.91  ? 276 ASN B N   1 
ATOM 4806 C CA  . ASN D 4 140 ? -95.696  26.999  -13.907 1.00 53.48  ? 276 ASN B CA  1 
ATOM 4807 C C   . ASN D 4 140 ? -95.334  28.343  -13.288 1.00 58.77  ? 276 ASN B C   1 
ATOM 4808 O O   . ASN D 4 140 ? -96.140  29.278  -13.354 1.00 65.50  ? 276 ASN B O   1 
ATOM 4809 C CB  . ASN D 4 140 ? -96.723  26.289  -13.027 1.00 57.29  ? 276 ASN B CB  1 
ATOM 4810 C CG  . ASN D 4 140 ? -97.399  25.141  -13.738 1.00 61.66  ? 276 ASN B CG  1 
ATOM 4811 O OD1 . ASN D 4 140 ? -97.355  25.044  -14.963 1.00 69.58  ? 276 ASN B OD1 1 
ATOM 4812 N ND2 . ASN D 4 140 ? -98.021  24.252  -12.969 1.00 76.03  ? 276 ASN B ND2 1 
ATOM 4813 N N   . ASN D 4 141 ? -94.148  28.462  -12.699 1.00 49.30  ? 277 ASN B N   1 
ATOM 4814 C CA  . ASN D 4 141 ? -93.717  29.654  -11.975 1.00 53.76  ? 277 ASN B CA  1 
ATOM 4815 C C   . ASN D 4 141 ? -92.330  30.085  -12.440 1.00 54.14  ? 277 ASN B C   1 
ATOM 4816 O O   . ASN D 4 141 ? -91.420  30.326  -11.641 1.00 51.93  ? 277 ASN B O   1 
ATOM 4817 C CB  . ASN D 4 141 ? -93.753  29.403  -10.470 1.00 50.08  ? 277 ASN B CB  1 
ATOM 4818 C CG  . ASN D 4 141 ? -95.153  29.103  -9.964  1.00 49.71  ? 277 ASN B CG  1 
ATOM 4819 O OD1 . ASN D 4 141 ? -95.936  30.015  -9.695  1.00 64.35  ? 277 ASN B OD1 1 
ATOM 4820 N ND2 . ASN D 4 141 ? -95.478  27.822  -9.841  1.00 45.35  ? 277 ASN B ND2 1 
ATOM 4821 N N   . VAL D 4 142 ? -92.165  30.184  -13.764 1.00 48.59  ? 278 VAL B N   1 
ATOM 4822 C CA  . VAL D 4 142 ? -90.873  30.528  -14.356 1.00 43.83  ? 278 VAL B CA  1 
ATOM 4823 C C   . VAL D 4 142 ? -90.383  31.882  -13.850 1.00 47.15  ? 278 VAL B C   1 
ATOM 4824 O O   . VAL D 4 142 ? -89.185  32.071  -13.601 1.00 47.07  ? 278 VAL B O   1 
ATOM 4825 C CB  . VAL D 4 142 ? -90.975  30.494  -15.895 1.00 49.04  ? 278 VAL B CB  1 
ATOM 4826 C CG1 . VAL D 4 142 ? -89.883  31.338  -16.538 1.00 54.07  ? 278 VAL B CG1 1 
ATOM 4827 C CG2 . VAL D 4 142 ? -90.899  29.062  -16.401 1.00 46.23  ? 278 VAL B CG2 1 
ATOM 4828 N N   . GLN D 4 143 ? -91.296  32.846  -13.689 1.00 48.40  ? 279 GLN B N   1 
ATOM 4829 C CA  . GLN D 4 143 ? -90.886  34.178  -13.249 1.00 55.85  ? 279 GLN B CA  1 
ATOM 4830 C C   . GLN D 4 143 ? -90.297  34.143  -11.841 1.00 52.16  ? 279 GLN B C   1 
ATOM 4831 O O   . GLN D 4 143 ? -89.345  34.875  -11.544 1.00 52.37  ? 279 GLN B O   1 
ATOM 4832 C CB  . GLN D 4 143 ? -92.065  35.152  -13.321 1.00 59.18  ? 279 GLN B CB  1 
ATOM 4833 C CG  . GLN D 4 143 ? -93.165  34.899  -12.303 1.00 67.83  ? 279 GLN B CG  1 
ATOM 4834 C CD  . GLN D 4 143 ? -94.168  33.871  -12.769 1.00 71.92  ? 279 GLN B CD  1 
ATOM 4835 O OE1 . GLN D 4 143 ? -93.971  33.213  -13.790 1.00 76.49  ? 279 GLN B OE1 1 
ATOM 4836 N NE2 . GLN D 4 143 ? -95.248  33.714  -12.013 1.00 86.33  ? 279 GLN B NE2 1 
ATOM 4837 N N   . ILE D 4 144 ? -90.855  33.311  -10.956 1.00 46.35  ? 280 ILE B N   1 
ATOM 4838 C CA  . ILE D 4 144 ? -90.275  33.151  -9.626  1.00 40.37  ? 280 ILE B CA  1 
ATOM 4839 C C   . ILE D 4 144 ? -88.938  32.427  -9.715  1.00 46.86  ? 280 ILE B C   1 
ATOM 4840 O O   . ILE D 4 144 ? -87.983  32.771  -9.008  1.00 52.69  ? 280 ILE B O   1 
ATOM 4841 C CB  . ILE D 4 144 ? -91.257  32.419  -8.690  1.00 45.51  ? 280 ILE B CB  1 
ATOM 4842 C CG1 . ILE D 4 144 ? -92.635  33.084  -8.717  1.00 48.10  ? 280 ILE B CG1 1 
ATOM 4843 C CG2 . ILE D 4 144 ? -90.708  32.369  -7.270  1.00 38.25  ? 280 ILE B CG2 1 
ATOM 4844 C CD1 . ILE D 4 144 ? -92.653  34.485  -8.135  1.00 53.14  ? 280 ILE B CD1 1 
ATOM 4845 N N   . VAL D 4 145 ? -88.844  31.421  -10.592 1.00 40.03  ? 281 VAL B N   1 
ATOM 4846 C CA  . VAL D 4 145 ? -87.585  30.699  -10.773 1.00 41.08  ? 281 VAL B CA  1 
ATOM 4847 C C   . VAL D 4 145 ? -86.479  31.657  -11.200 1.00 48.94  ? 281 VAL B C   1 
ATOM 4848 O O   . VAL D 4 145 ? -85.350  31.589  -10.698 1.00 50.60  ? 281 VAL B O   1 
ATOM 4849 C CB  . VAL D 4 145 ? -87.766  29.553  -11.787 1.00 35.96  ? 281 VAL B CB  1 
ATOM 4850 C CG1 . VAL D 4 145 ? -86.415  29.009  -12.234 1.00 23.42  ? 281 VAL B CG1 1 
ATOM 4851 C CG2 . VAL D 4 145 ? -88.624  28.444  -11.193 1.00 39.56  ? 281 VAL B CG2 1 
ATOM 4852 N N   . ARG D 4 146 ? -86.787  32.575  -12.122 1.00 48.81  ? 282 ARG B N   1 
ATOM 4853 C CA  . ARG D 4 146 ? -85.796  33.567  -12.527 1.00 46.95  ? 282 ARG B CA  1 
ATOM 4854 C C   . ARG D 4 146 ? -85.367  34.429  -11.351 1.00 42.85  ? 282 ARG B C   1 
ATOM 4855 O O   . ARG D 4 146 ? -84.177  34.717  -11.186 1.00 41.50  ? 282 ARG B O   1 
ATOM 4856 C CB  . ARG D 4 146 ? -86.348  34.451  -13.641 1.00 48.52  ? 282 ARG B CB  1 
ATOM 4857 C CG  . ARG D 4 146 ? -86.372  33.795  -14.994 1.00 49.16  ? 282 ARG B CG  1 
ATOM 4858 C CD  . ARG D 4 146 ? -86.812  34.783  -16.046 1.00 44.32  ? 282 ARG B CD  1 
ATOM 4859 N NE  . ARG D 4 146 ? -87.062  34.121  -17.318 1.00 56.77  ? 282 ARG B NE  1 
ATOM 4860 C CZ  . ARG D 4 146 ? -86.119  33.786  -18.186 1.00 44.79  ? 282 ARG B CZ  1 
ATOM 4861 N NH1 . ARG D 4 146 ? -84.840  34.024  -17.943 1.00 41.96  ? 282 ARG B NH1 1 
ATOM 4862 N NH2 . ARG D 4 146 ? -86.467  33.192  -19.323 1.00 62.85  ? 282 ARG B NH2 1 
ATOM 4863 N N   . GLN D 4 147 ? -86.328  34.850  -10.525 1.00 45.25  ? 283 GLN B N   1 
ATOM 4864 C CA  . GLN D 4 147 ? -86.027  35.733  -9.405  1.00 36.66  ? 283 GLN B CA  1 
ATOM 4865 C C   . GLN D 4 147 ? -85.132  35.059  -8.371  1.00 37.11  ? 283 GLN B C   1 
ATOM 4866 O O   . GLN D 4 147 ? -84.364  35.740  -7.684  1.00 47.84  ? 283 GLN B O   1 
ATOM 4867 C CB  . GLN D 4 147 ? -87.332  36.211  -8.770  1.00 32.25  ? 283 GLN B CB  1 
ATOM 4868 C CG  . GLN D 4 147 ? -88.009  37.339  -9.534  1.00 37.01  ? 283 GLN B CG  1 
ATOM 4869 C CD  . GLN D 4 147 ? -89.114  38.013  -8.743  1.00 52.69  ? 283 GLN B CD  1 
ATOM 4870 O OE1 . GLN D 4 147 ? -89.989  37.348  -8.188  1.00 56.53  ? 283 GLN B OE1 1 
ATOM 4871 N NE2 . GLN D 4 147 ? -89.077  39.340  -8.684  1.00 69.43  ? 283 GLN B NE2 1 
ATOM 4872 N N   . GLN D 4 148 ? -85.197  33.732  -8.256  1.00 35.10  ? 284 GLN B N   1 
ATOM 4873 C CA  . GLN D 4 148 ? -84.392  32.995  -7.291  1.00 38.59  ? 284 GLN B CA  1 
ATOM 4874 C C   . GLN D 4 148 ? -83.198  32.307  -7.946  1.00 37.86  ? 284 GLN B C   1 
ATOM 4875 O O   . GLN D 4 148 ? -82.820  31.200  -7.548  1.00 38.99  ? 284 GLN B O   1 
ATOM 4876 C CB  . GLN D 4 148 ? -85.256  31.971  -6.556  1.00 42.87  ? 284 GLN B CB  1 
ATOM 4877 C CG  . GLN D 4 148 ? -86.558  32.538  -6.006  1.00 48.28  ? 284 GLN B CG  1 
ATOM 4878 C CD  . GLN D 4 148 ? -87.261  31.571  -5.077  1.00 54.27  ? 284 GLN B CD  1 
ATOM 4879 O OE1 . GLN D 4 148 ? -87.843  30.581  -5.520  1.00 57.79  ? 284 GLN B OE1 1 
ATOM 4880 N NE2 . GLN D 4 148 ? -87.237  31.869  -3.782  1.00 48.46  ? 284 GLN B NE2 1 
ATOM 4881 N N   . SER D 4 149 ? -82.600  32.937  -8.954  1.00 46.73  ? 285 SER B N   1 
ATOM 4882 C CA  . SER D 4 149 ? -81.501  32.343  -9.702  1.00 48.04  ? 285 SER B CA  1 
ATOM 4883 C C   . SER D 4 149 ? -80.379  33.353  -9.880  1.00 45.00  ? 285 SER B C   1 
ATOM 4884 O O   . SER D 4 149 ? -80.607  34.565  -9.918  1.00 48.65  ? 285 SER B O   1 
ATOM 4885 C CB  . SER D 4 149 ? -81.956  31.845  -11.078 1.00 34.82  ? 285 SER B CB  1 
ATOM 4886 O OG  . SER D 4 149 ? -82.888  30.788  -10.966 1.00 42.95  ? 285 SER B OG  1 
ATOM 4887 N N   . TYR D 4 150 ? -79.162  32.836  -9.999  1.00 35.31  ? 286 TYR B N   1 
ATOM 4888 C CA  . TYR D 4 150 ? -77.987  33.651  -10.253 1.00 42.84  ? 286 TYR B CA  1 
ATOM 4889 C C   . TYR D 4 150 ? -77.353  33.236  -11.574 1.00 51.32  ? 286 TYR B C   1 
ATOM 4890 O O   . TYR D 4 150 ? -77.448  32.078  -11.992 1.00 48.06  ? 286 TYR B O   1 
ATOM 4891 C CB  . TYR D 4 150 ? -76.953  33.525  -9.127  1.00 44.52  ? 286 TYR B CB  1 
ATOM 4892 C CG  . TYR D 4 150 ? -77.396  34.061  -7.781  1.00 49.30  ? 286 TYR B CG  1 
ATOM 4893 C CD1 . TYR D 4 150 ? -78.085  33.255  -6.882  1.00 40.11  ? 286 TYR B CD1 1 
ATOM 4894 C CD2 . TYR D 4 150 ? -77.105  35.365  -7.401  1.00 45.62  ? 286 TYR B CD2 1 
ATOM 4895 C CE1 . TYR D 4 150 ? -78.482  33.735  -5.651  1.00 39.94  ? 286 TYR B CE1 1 
ATOM 4896 C CE2 . TYR D 4 150 ? -77.498  35.854  -6.169  1.00 48.78  ? 286 TYR B CE2 1 
ATOM 4897 C CZ  . TYR D 4 150 ? -78.187  35.035  -5.298  1.00 50.49  ? 286 TYR B CZ  1 
ATOM 4898 O OH  . TYR D 4 150 ? -78.580  35.519  -4.067  1.00 58.64  ? 286 TYR B OH  1 
ATOM 4899 N N   . SER D 4 151 ? -76.711  34.197  -12.232 1.00 44.24  ? 287 SER B N   1 
ATOM 4900 C CA  . SER D 4 151 ? -75.935  33.945  -13.440 1.00 40.77  ? 287 SER B CA  1 
ATOM 4901 C C   . SER D 4 151 ? -74.507  34.397  -13.169 1.00 40.91  ? 287 SER B C   1 
ATOM 4902 O O   . SER D 4 151 ? -74.252  35.596  -13.011 1.00 47.87  ? 287 SER B O   1 
ATOM 4903 C CB  . SER D 4 151 ? -76.530  34.676  -14.642 1.00 50.73  ? 287 SER B CB  1 
ATOM 4904 O OG  . SER D 4 151 ? -75.693  34.542  -15.774 1.00 56.02  ? 287 SER B OG  1 
ATOM 4905 N N   . ILE D 4 152 ? -73.582  33.443  -13.109 1.00 38.36  ? 288 ILE B N   1 
ATOM 4906 C CA  . ILE D 4 152 ? -72.183  33.715  -12.804 1.00 48.25  ? 288 ILE B CA  1 
ATOM 4907 C C   . ILE D 4 152 ? -71.365  33.456  -14.060 1.00 38.62  ? 288 ILE B C   1 
ATOM 4908 O O   . ILE D 4 152 ? -71.464  32.383  -14.665 1.00 43.55  ? 288 ILE B O   1 
ATOM 4909 C CB  . ILE D 4 152 ? -71.678  32.860  -11.628 1.00 41.33  ? 288 ILE B CB  1 
ATOM 4910 C CG1 . ILE D 4 152 ? -72.526  33.109  -10.382 1.00 39.67  ? 288 ILE B CG1 1 
ATOM 4911 C CG2 . ILE D 4 152 ? -70.221  33.167  -11.332 1.00 44.59  ? 288 ILE B CG2 1 
ATOM 4912 C CD1 . ILE D 4 152 ? -73.522  32.011  -10.103 1.00 40.87  ? 288 ILE B CD1 1 
ATOM 4913 N N   . MET D 4 153 ? -70.564  34.441  -14.451 1.00 44.70  ? 289 MET B N   1 
ATOM 4914 C CA  . MET D 4 153 ? -69.723  34.335  -15.636 1.00 45.46  ? 289 MET B CA  1 
ATOM 4915 C C   . MET D 4 153 ? -68.436  33.592  -15.288 1.00 52.48  ? 289 MET B C   1 
ATOM 4916 O O   . MET D 4 153 ? -67.693  34.020  -14.397 1.00 67.91  ? 289 MET B O   1 
ATOM 4917 C CB  . MET D 4 153 ? -69.423  35.732  -16.174 1.00 38.59  ? 289 MET B CB  1 
ATOM 4918 C CG  . MET D 4 153 ? -68.245  35.794  -17.119 1.00 79.95  ? 289 MET B CG  1 
ATOM 4919 S SD  . MET D 4 153 ? -68.512  35.003  -18.723 1.00 82.08  ? 289 MET B SD  1 
ATOM 4920 C CE  . MET D 4 153 ? -70.218  35.410  -19.042 1.00 51.91  ? 289 MET B CE  1 
ATOM 4921 N N   . CYS D 4 154 ? -68.171  32.479  -15.980 1.00 51.76  ? 290 CYS B N   1 
ATOM 4922 C CA  . CYS D 4 154 ? -67.027  31.633  -15.636 1.00 62.85  ? 290 CYS B CA  1 
ATOM 4923 C C   . CYS D 4 154 ? -65.777  31.951  -16.453 1.00 58.75  ? 290 CYS B C   1 
ATOM 4924 O O   . CYS D 4 154 ? -64.747  32.343  -15.896 1.00 70.06  ? 290 CYS B O   1 
ATOM 4925 C CB  . CYS D 4 154 ? -67.368  30.147  -15.819 1.00 39.08  ? 290 CYS B CB  1 
ATOM 4926 S SG  . CYS D 4 154 ? -68.485  29.377  -14.618 1.00 114.97 ? 290 CYS B SG  1 
ATOM 4927 N N   . ILE D 4 155 ? -65.842  31.772  -17.772 1.00 55.47  ? 291 ILE B N   1 
ATOM 4928 C CA  . ILE D 4 155 ? -64.627  31.670  -18.571 1.00 59.40  ? 291 ILE B CA  1 
ATOM 4929 C C   . ILE D 4 155 ? -64.945  32.070  -20.001 1.00 54.19  ? 291 ILE B C   1 
ATOM 4930 O O   . ILE D 4 155 ? -66.068  31.888  -20.478 1.00 60.16  ? 291 ILE B O   1 
ATOM 4931 C CB  . ILE D 4 155 ? -64.041  30.236  -18.496 1.00 64.94  ? 291 ILE B CB  1 
ATOM 4932 C CG1 . ILE D 4 155 ? -62.666  30.164  -19.164 1.00 65.62  ? 291 ILE B CG1 1 
ATOM 4933 C CG2 . ILE D 4 155 ? -64.995  29.236  -19.140 1.00 52.41  ? 291 ILE B CG2 1 
ATOM 4934 C CD1 . ILE D 4 155 ? -61.676  31.178  -18.633 1.00 82.25  ? 291 ILE B CD1 1 
ATOM 4935 N N   . ILE D 4 156 ? -63.943  32.620  -20.687 1.00 62.87  ? 292 ILE B N   1 
ATOM 4936 C CA  . ILE D 4 156 ? -64.019  32.830  -22.128 1.00 68.36  ? 292 ILE B CA  1 
ATOM 4937 C C   . ILE D 4 156 ? -62.697  32.396  -22.755 1.00 54.32  ? 292 ILE B C   1 
ATOM 4938 O O   . ILE D 4 156 ? -61.702  33.129  -22.730 1.00 58.43  ? 292 ILE B O   1 
ATOM 4939 C CB  . ILE D 4 156 ? -64.382  34.292  -22.465 1.00 56.99  ? 292 ILE B CB  1 
ATOM 4940 C CG1 . ILE D 4 156 ? -64.390  34.519  -23.971 1.00 54.60  ? 292 ILE B CG1 1 
ATOM 4941 C CG2 . ILE D 4 156 ? -63.469  35.291  -21.756 1.00 65.96  ? 292 ILE B CG2 1 
ATOM 4942 C CD1 . ILE D 4 156 ? -64.761  35.932  -24.338 1.00 79.66  ? 292 ILE B CD1 1 
ATOM 4943 N N   . LYS D 4 157 ? -62.669  31.182  -23.298 1.00 56.65  ? 293 LYS B N   1 
ATOM 4944 C CA  . LYS D 4 157 ? -61.446  30.657  -23.886 1.00 59.33  ? 293 LYS B CA  1 
ATOM 4945 C C   . LYS D 4 157 ? -61.797  29.556  -24.875 1.00 61.88  ? 293 LYS B C   1 
ATOM 4946 O O   . LYS D 4 157 ? -62.892  28.986  -24.837 1.00 64.21  ? 293 LYS B O   1 
ATOM 4947 C CB  . LYS D 4 157 ? -60.490  30.131  -22.811 1.00 63.46  ? 293 LYS B CB  1 
ATOM 4948 C CG  . LYS D 4 157 ? -60.759  28.701  -22.373 1.00 54.55  ? 293 LYS B CG  1 
ATOM 4949 C CD  . LYS D 4 157 ? -59.576  28.158  -21.589 1.00 60.12  ? 293 LYS B CD  1 
ATOM 4950 C CE  . LYS D 4 157 ? -59.604  26.647  -21.520 1.00 58.75  ? 293 LYS B CE  1 
ATOM 4951 N NZ  . LYS D 4 157 ? -58.880  26.131  -20.328 1.00 72.95  ? 293 LYS B NZ  1 
ATOM 4952 N N   . GLU D 4 158 ? -60.843  29.267  -25.762 1.00 71.79  ? 294 GLU B N   1 
ATOM 4953 C CA  . GLU D 4 158 ? -60.980  28.206  -26.763 1.00 73.54  ? 294 GLU B CA  1 
ATOM 4954 C C   . GLU D 4 158 ? -62.229  28.402  -27.620 1.00 61.05  ? 294 GLU B C   1 
ATOM 4955 O O   . GLU D 4 158 ? -62.945  27.447  -27.932 1.00 60.89  ? 294 GLU B O   1 
ATOM 4956 C CB  . GLU D 4 158 ? -60.986  26.827  -26.100 1.00 72.76  ? 294 GLU B CB  1 
ATOM 4957 C CG  . GLU D 4 158 ? -59.611  26.331  -25.687 1.00 76.10  ? 294 GLU B CG  1 
ATOM 4958 C CD  . GLU D 4 158 ? -58.922  25.554  -26.789 1.00 101.26 ? 294 GLU B CD  1 
ATOM 4959 O OE1 . GLU D 4 158 ? -59.606  25.171  -27.762 1.00 108.24 ? 294 GLU B OE1 1 
ATOM 4960 O OE2 . GLU D 4 158 ? -57.697  25.329  -26.687 1.00 123.76 ? 294 GLU B OE2 1 
ATOM 4961 N N   . GLU D 4 159 ? -62.492  29.654  -28.001 1.00 51.11  ? 295 GLU B N   1 
ATOM 4962 C CA  . GLU D 4 159 ? -63.664  30.019  -28.799 1.00 55.42  ? 295 GLU B CA  1 
ATOM 4963 C C   . GLU D 4 159 ? -64.966  29.649  -28.096 1.00 55.81  ? 295 GLU B C   1 
ATOM 4964 O O   . GLU D 4 159 ? -65.974  29.356  -28.742 1.00 59.16  ? 295 GLU B O   1 
ATOM 4965 C CB  . GLU D 4 159 ? -63.612  29.382  -30.191 1.00 66.86  ? 295 GLU B CB  1 
ATOM 4966 C CG  . GLU D 4 159 ? -62.494  29.912  -31.068 1.00 82.23  ? 295 GLU B CG  1 
ATOM 4967 C CD  . GLU D 4 159 ? -62.074  28.922  -32.136 1.00 94.10  ? 295 GLU B CD  1 
ATOM 4968 O OE1 . GLU D 4 159 ? -61.623  27.814  -31.775 1.00 98.13  ? 295 GLU B OE1 1 
ATOM 4969 O OE2 . GLU D 4 159 ? -62.188  29.254  -33.336 1.00 94.60  ? 295 GLU B OE2 1 
ATOM 4970 N N   . VAL D 4 160 ? -64.958  29.657  -26.766 1.00 68.12  ? 296 VAL B N   1 
ATOM 4971 C CA  . VAL D 4 160 ? -66.134  29.325  -25.973 1.00 57.45  ? 296 VAL B CA  1 
ATOM 4972 C C   . VAL D 4 160 ? -66.311  30.392  -24.903 1.00 53.05  ? 296 VAL B C   1 
ATOM 4973 O O   . VAL D 4 160 ? -65.365  30.713  -24.176 1.00 51.14  ? 296 VAL B O   1 
ATOM 4974 C CB  . VAL D 4 160 ? -66.020  27.926  -25.336 1.00 51.43  ? 296 VAL B CB  1 
ATOM 4975 C CG1 . VAL D 4 160 ? -66.851  27.843  -24.061 1.00 57.97  ? 296 VAL B CG1 1 
ATOM 4976 C CG2 . VAL D 4 160 ? -66.457  26.858  -26.325 1.00 64.48  ? 296 VAL B CG2 1 
ATOM 4977 N N   . LEU D 4 161 ? -67.515  30.948  -24.820 1.00 52.38  ? 297 LEU B N   1 
ATOM 4978 C CA  . LEU D 4 161 ? -67.911  31.837  -23.738 1.00 51.06  ? 297 LEU B CA  1 
ATOM 4979 C C   . LEU D 4 161 ? -68.901  31.084  -22.863 1.00 50.18  ? 297 LEU B C   1 
ATOM 4980 O O   . LEU D 4 161 ? -69.983  30.712  -23.331 1.00 55.39  ? 297 LEU B O   1 
ATOM 4981 C CB  . LEU D 4 161 ? -68.533  33.122  -24.283 1.00 49.56  ? 297 LEU B CB  1 
ATOM 4982 C CG  . LEU D 4 161 ? -69.383  33.917  -23.291 1.00 56.37  ? 297 LEU B CG  1 
ATOM 4983 C CD1 . LEU D 4 161 ? -68.527  34.422  -22.149 1.00 67.01  ? 297 LEU B CD1 1 
ATOM 4984 C CD2 . LEU D 4 161 ? -70.089  35.064  -23.986 1.00 58.86  ? 297 LEU B CD2 1 
ATOM 4985 N N   . ALA D 4 162 ? -68.532  30.857  -21.602 1.00 44.96  ? 298 ALA B N   1 
ATOM 4986 C CA  . ALA D 4 162 ? -69.304  30.015  -20.696 1.00 40.66  ? 298 ALA B CA  1 
ATOM 4987 C C   . ALA D 4 162 ? -69.646  30.772  -19.423 1.00 46.26  ? 298 ALA B C   1 
ATOM 4988 O O   . ALA D 4 162 ? -68.771  31.386  -18.804 1.00 58.15  ? 298 ALA B O   1 
ATOM 4989 C CB  . ALA D 4 162 ? -68.538  28.739  -20.339 1.00 41.61  ? 298 ALA B CB  1 
ATOM 4990 N N   . TYR D 4 163 ? -70.915  30.714  -19.033 1.00 50.60  ? 299 TYR B N   1 
ATOM 4991 C CA  . TYR D 4 163 ? -71.359  31.189  -17.732 1.00 48.21  ? 299 TYR B CA  1 
ATOM 4992 C C   . TYR D 4 163 ? -72.296  30.150  -17.134 1.00 46.42  ? 299 TYR B C   1 
ATOM 4993 O O   . TYR D 4 163 ? -73.026  29.466  -17.856 1.00 47.31  ? 299 TYR B O   1 
ATOM 4994 C CB  . TYR D 4 163 ? -72.050  32.557  -17.831 1.00 39.88  ? 299 TYR B CB  1 
ATOM 4995 C CG  . TYR D 4 163 ? -73.170  32.618  -18.845 1.00 47.41  ? 299 TYR B CG  1 
ATOM 4996 C CD1 . TYR D 4 163 ? -72.894  32.865  -20.186 1.00 48.81  ? 299 TYR B CD1 1 
ATOM 4997 C CD2 . TYR D 4 163 ? -74.501  32.468  -18.464 1.00 38.16  ? 299 TYR B CD2 1 
ATOM 4998 C CE1 . TYR D 4 163 ? -73.899  32.928  -21.126 1.00 40.21  ? 299 TYR B CE1 1 
ATOM 4999 C CE2 . TYR D 4 163 ? -75.523  32.537  -19.402 1.00 44.61  ? 299 TYR B CE2 1 
ATOM 5000 C CZ  . TYR D 4 163 ? -75.211  32.767  -20.734 1.00 56.86  ? 299 TYR B CZ  1 
ATOM 5001 O OH  . TYR D 4 163 ? -76.206  32.837  -21.685 1.00 39.40  ? 299 TYR B OH  1 
ATOM 5002 N N   . VAL D 4 164 ? -72.264  30.025  -15.810 1.00 49.26  ? 300 VAL B N   1 
ATOM 5003 C CA  . VAL D 4 164 ? -73.116  29.077  -15.097 1.00 54.07  ? 300 VAL B CA  1 
ATOM 5004 C C   . VAL D 4 164 ? -74.385  29.787  -14.656 1.00 37.29  ? 300 VAL B C   1 
ATOM 5005 O O   . VAL D 4 164 ? -74.332  30.903  -14.125 1.00 37.71  ? 300 VAL B O   1 
ATOM 5006 C CB  . VAL D 4 164 ? -72.395  28.447  -13.891 1.00 43.67  ? 300 VAL B CB  1 
ATOM 5007 C CG1 . VAL D 4 164 ? -71.433  27.357  -14.351 1.00 57.56  ? 300 VAL B CG1 1 
ATOM 5008 C CG2 . VAL D 4 164 ? -71.673  29.505  -13.082 1.00 56.82  ? 300 VAL B CG2 1 
ATOM 5009 N N   . VAL D 4 165 ? -75.525  29.147  -14.893 1.00 37.34  ? 301 VAL B N   1 
ATOM 5010 C CA  . VAL D 4 165 ? -76.804  29.587  -14.354 1.00 40.15  ? 301 VAL B CA  1 
ATOM 5011 C C   . VAL D 4 165 ? -77.141  28.682  -13.179 1.00 51.85  ? 301 VAL B C   1 
ATOM 5012 O O   . VAL D 4 165 ? -77.284  27.464  -13.339 1.00 55.95  ? 301 VAL B O   1 
ATOM 5013 C CB  . VAL D 4 165 ? -77.910  29.554  -15.418 1.00 42.23  ? 301 VAL B CB  1 
ATOM 5014 C CG1 . VAL D 4 165 ? -79.274  29.702  -14.759 1.00 49.90  ? 301 VAL B CG1 1 
ATOM 5015 C CG2 . VAL D 4 165 ? -77.686  30.650  -16.439 1.00 53.81  ? 301 VAL B CG2 1 
ATOM 5016 N N   . GLN D 4 166 ? -77.264  29.277  -12.000 1.00 48.17  ? 302 GLN B N   1 
ATOM 5017 C CA  . GLN D 4 166 ? -77.485  28.550  -10.754 1.00 36.44  ? 302 GLN B CA  1 
ATOM 5018 C C   . GLN D 4 166 ? -78.974  28.626  -10.431 1.00 42.86  ? 302 GLN B C   1 
ATOM 5019 O O   . GLN D 4 166 ? -79.474  29.666  -9.995  1.00 43.23  ? 302 GLN B O   1 
ATOM 5020 C CB  . GLN D 4 166 ? -76.615  29.151  -9.656  1.00 37.61  ? 302 GLN B CB  1 
ATOM 5021 C CG  . GLN D 4 166 ? -76.787  28.567  -8.281  1.00 55.56  ? 302 GLN B CG  1 
ATOM 5022 C CD  . GLN D 4 166 ? -75.805  29.167  -7.292  1.00 55.12  ? 302 GLN B CD  1 
ATOM 5023 O OE1 . GLN D 4 166 ? -74.670  29.489  -7.648  1.00 53.73  ? 302 GLN B OE1 1 
ATOM 5024 N NE2 . GLN D 4 166 ? -76.245  29.347  -6.051  1.00 47.75  ? 302 GLN B NE2 1 
ATOM 5025 N N   . LEU D 4 167 ? -79.714  27.483  -10.680 1.00 42.95  ? 303 LEU B N   1 
ATOM 5026 C CA  . LEU D 4 167 ? -81.159  27.359  -10.547 1.00 44.29  ? 303 LEU B CA  1 
ATOM 5027 C C   . LEU D 4 167 ? -81.545  26.833  -9.165  1.00 45.99  ? 303 LEU B C   1 
ATOM 5028 O O   . LEU D 4 167 ? -80.779  26.096  -8.535  1.00 47.63  ? 303 LEU B O   1 
ATOM 5029 C CB  . LEU D 4 167 ? -81.714  26.430  -11.631 1.00 44.72  ? 303 LEU B CB  1 
ATOM 5030 C CG  . LEU D 4 167 ? -81.536  26.906  -13.083 1.00 54.04  ? 303 LEU B CG  1 
ATOM 5031 C CD1 . LEU D 4 167 ? -81.962  25.847  -14.091 1.00 44.33  ? 303 LEU B CD1 1 
ATOM 5032 C CD2 . LEU D 4 167 ? -82.321  28.186  -13.313 1.00 45.37  ? 303 LEU B CD2 1 
ATOM 5033 N N   . PRO D 4 168 ? -82.722  27.214  -8.671  1.00 50.90  ? 304 PRO B N   1 
ATOM 5034 C CA  . PRO D 4 168 ? -83.182  26.715  -7.372  1.00 42.57  ? 304 PRO B CA  1 
ATOM 5035 C C   . PRO D 4 168 ? -83.680  25.279  -7.433  1.00 38.96  ? 304 PRO B C   1 
ATOM 5036 O O   . PRO D 4 168 ? -84.192  24.809  -8.450  1.00 45.61  ? 304 PRO B O   1 
ATOM 5037 C CB  . PRO D 4 168 ? -84.329  27.670  -7.022  1.00 37.67  ? 304 PRO B CB  1 
ATOM 5038 C CG  . PRO D 4 168 ? -84.855  28.114  -8.334  1.00 44.41  ? 304 PRO B CG  1 
ATOM 5039 C CD  . PRO D 4 168 ? -83.665  28.182  -9.259  1.00 44.75  ? 304 PRO B CD  1 
ATOM 5040 N N   . LEU D 4 169 ? -83.530  24.584  -6.307  1.00 51.15  ? 305 LEU B N   1 
ATOM 5041 C CA  . LEU D 4 169 ? -84.106  23.260  -6.102  1.00 51.55  ? 305 LEU B CA  1 
ATOM 5042 C C   . LEU D 4 169 ? -85.124  23.348  -4.975  1.00 53.12  ? 305 LEU B C   1 
ATOM 5043 O O   . LEU D 4 169 ? -84.760  23.626  -3.827  1.00 58.17  ? 305 LEU B O   1 
ATOM 5044 C CB  . LEU D 4 169 ? -83.033  22.223  -5.766  1.00 51.20  ? 305 LEU B CB  1 
ATOM 5045 C CG  . LEU D 4 169 ? -81.956  21.964  -6.815  1.00 60.09  ? 305 LEU B CG  1 
ATOM 5046 C CD1 . LEU D 4 169 ? -80.799  21.203  -6.191  1.00 54.90  ? 305 LEU B CD1 1 
ATOM 5047 C CD2 . LEU D 4 169 ? -82.541  21.202  -7.994  1.00 49.89  ? 305 LEU B CD2 1 
ATOM 5048 N N   . TYR D 4 170 ? -86.392  23.106  -5.300  1.00 51.77  ? 306 TYR B N   1 
ATOM 5049 C CA  . TYR D 4 170 ? -87.468  23.171  -4.312  1.00 45.46  ? 306 TYR B CA  1 
ATOM 5050 C C   . TYR D 4 170 ? -87.673  21.778  -3.731  1.00 50.91  ? 306 TYR B C   1 
ATOM 5051 O O   . TYR D 4 170 ? -88.502  20.996  -4.200  1.00 44.97  ? 306 TYR B O   1 
ATOM 5052 C CB  . TYR D 4 170 ? -88.739  23.730  -4.937  1.00 37.72  ? 306 TYR B CB  1 
ATOM 5053 C CG  . TYR D 4 170 ? -88.538  25.093  -5.562  1.00 49.12  ? 306 TYR B CG  1 
ATOM 5054 C CD1 . TYR D 4 170 ? -88.531  26.242  -4.781  1.00 45.44  ? 306 TYR B CD1 1 
ATOM 5055 C CD2 . TYR D 4 170 ? -88.351  25.230  -6.932  1.00 56.13  ? 306 TYR B CD2 1 
ATOM 5056 C CE1 . TYR D 4 170 ? -88.345  27.489  -5.345  1.00 43.86  ? 306 TYR B CE1 1 
ATOM 5057 C CE2 . TYR D 4 170 ? -88.163  26.474  -7.507  1.00 49.78  ? 306 TYR B CE2 1 
ATOM 5058 C CZ  . TYR D 4 170 ? -88.162  27.600  -6.707  1.00 54.78  ? 306 TYR B CZ  1 
ATOM 5059 O OH  . TYR D 4 170 ? -87.976  28.840  -7.277  1.00 49.05  ? 306 TYR B OH  1 
ATOM 5060 N N   . GLY D 4 171 ? -86.899  21.467  -2.685  1.00 50.71  ? 307 GLY B N   1 
ATOM 5061 C CA  . GLY D 4 171 ? -86.984  20.165  -2.046  1.00 56.21  ? 307 GLY B CA  1 
ATOM 5062 C C   . GLY D 4 171 ? -88.142  20.003  -1.088  1.00 52.34  ? 307 GLY B C   1 
ATOM 5063 O O   . GLY D 4 171 ? -88.497  18.870  -0.750  1.00 73.98  ? 307 GLY B O   1 
ATOM 5064 N N   . VAL D 4 172 ? -88.738  21.103  -0.641  1.00 45.52  ? 308 VAL B N   1 
ATOM 5065 C CA  . VAL D 4 172 ? -89.918  21.073  0.214   1.00 51.46  ? 308 VAL B CA  1 
ATOM 5066 C C   . VAL D 4 172 ? -91.060  21.695  -0.574  1.00 57.36  ? 308 VAL B C   1 
ATOM 5067 O O   . VAL D 4 172 ? -90.975  22.859  -0.986  1.00 57.81  ? 308 VAL B O   1 
ATOM 5068 C CB  . VAL D 4 172 ? -89.683  21.810  1.543   1.00 52.86  ? 308 VAL B CB  1 
ATOM 5069 C CG1 . VAL D 4 172 ? -90.965  21.864  2.361   1.00 35.89  ? 308 VAL B CG1 1 
ATOM 5070 C CG2 . VAL D 4 172 ? -88.568  21.137  2.325   1.00 30.69  ? 308 VAL B CG2 1 
ATOM 5071 N N   . ILE D 4 173 ? -92.115  20.917  -0.801  1.00 66.73  ? 309 ILE B N   1 
ATOM 5072 C CA  . ILE D 4 173 ? -93.224  21.315  -1.662  1.00 63.53  ? 309 ILE B CA  1 
ATOM 5073 C C   . ILE D 4 173 ? -94.533  20.882  -1.016  1.00 67.23  ? 309 ILE B C   1 
ATOM 5074 O O   . ILE D 4 173 ? -94.618  19.801  -0.423  1.00 68.98  ? 309 ILE B O   1 
ATOM 5075 C CB  . ILE D 4 173 ? -93.080  20.714  -3.079  1.00 58.91  ? 309 ILE B CB  1 
ATOM 5076 C CG1 . ILE D 4 173 ? -91.860  21.300  -3.794  1.00 60.04  ? 309 ILE B CG1 1 
ATOM 5077 C CG2 . ILE D 4 173 ? -94.340  20.937  -3.903  1.00 65.55  ? 309 ILE B CG2 1 
ATOM 5078 C CD1 . ILE D 4 173 ? -91.762  20.903  -5.252  1.00 79.18  ? 309 ILE B CD1 1 
ATOM 5079 N N   . ASP D 4 174 ? -95.545  21.747  -1.109  1.00 64.74  ? 310 ASP B N   1 
ATOM 5080 C CA  . ASP D 4 174 ? -96.920  21.459  -0.712  1.00 61.48  ? 310 ASP B CA  1 
ATOM 5081 C C   . ASP D 4 174 ? -97.077  21.208  0.782   1.00 64.41  ? 310 ASP B C   1 
ATOM 5082 O O   . ASP D 4 174 ? -98.067  20.604  1.205   1.00 81.81  ? 310 ASP B O   1 
ATOM 5083 C CB  . ASP D 4 174 ? -97.492  20.276  -1.504  1.00 70.92  ? 310 ASP B CB  1 
ATOM 5084 C CG  . ASP D 4 174 ? -97.696  20.603  -2.972  1.00 86.72  ? 310 ASP B CG  1 
ATOM 5085 O OD1 . ASP D 4 174 ? -97.445  21.764  -3.362  1.00 83.39  ? 310 ASP B OD1 1 
ATOM 5086 O OD2 . ASP D 4 174 ? -98.105  19.703  -3.737  1.00 91.68  ? 310 ASP B OD2 1 
ATOM 5087 N N   . THR D 4 175 ? -96.129  21.654  1.601   1.00 59.87  ? 311 THR B N   1 
ATOM 5088 C CA  . THR D 4 175 ? -96.395  21.614  3.029   1.00 51.42  ? 311 THR B CA  1 
ATOM 5089 C C   . THR D 4 175 ? -97.183  22.862  3.430   1.00 59.50  ? 311 THR B C   1 
ATOM 5090 O O   . THR D 4 175 ? -97.078  23.905  2.777   1.00 55.53  ? 311 THR B O   1 
ATOM 5091 C CB  . THR D 4 175 ? -95.094  21.533  3.825   1.00 44.85  ? 311 THR B CB  1 
ATOM 5092 O OG1 . THR D 4 175 ? -94.365  22.759  3.700   1.00 50.04  ? 311 THR B OG1 1 
ATOM 5093 C CG2 . THR D 4 175 ? -94.228  20.402  3.295   1.00 43.12  ? 311 THR B CG2 1 
ATOM 5094 N N   . PRO D 4 176 ? -98.009  22.772  4.472   1.00 58.41  ? 312 PRO B N   1 
ATOM 5095 C CA  . PRO D 4 176 ? -98.815  23.934  4.868   1.00 60.13  ? 312 PRO B CA  1 
ATOM 5096 C C   . PRO D 4 176 ? -97.952  25.084  5.369   1.00 54.34  ? 312 PRO B C   1 
ATOM 5097 O O   . PRO D 4 176 ? -96.951  24.883  6.059   1.00 56.29  ? 312 PRO B O   1 
ATOM 5098 C CB  . PRO D 4 176 ? -99.717  23.379  5.976   1.00 40.04  ? 312 PRO B CB  1 
ATOM 5099 C CG  . PRO D 4 176 ? -98.979  22.196  6.502   1.00 50.07  ? 312 PRO B CG  1 
ATOM 5100 C CD  . PRO D 4 176 ? -98.290  21.597  5.314   1.00 57.47  ? 312 PRO B CD  1 
ATOM 5101 N N   . CYS D 4 177 ? -98.360  26.301  5.016   1.00 57.46  ? 313 CYS B N   1 
ATOM 5102 C CA  . CYS D 4 177 ? -97.688  27.519  5.439   1.00 50.01  ? 313 CYS B CA  1 
ATOM 5103 C C   . CYS D 4 177 ? -98.714  28.507  5.969   1.00 56.80  ? 313 CYS B C   1 
ATOM 5104 O O   . CYS D 4 177 ? -99.882  28.494  5.568   1.00 63.12  ? 313 CYS B O   1 
ATOM 5105 C CB  . CYS D 4 177 ? -96.902  28.181  4.294   1.00 48.96  ? 313 CYS B CB  1 
ATOM 5106 S SG  . CYS D 4 177 ? -95.516  27.228  3.654   1.00 77.84  ? 313 CYS B SG  1 
ATOM 5107 N N   . TRP D 4 178 ? -98.265  29.372  6.873   1.00 42.47  ? 314 TRP B N   1 
ATOM 5108 C CA  . TRP D 4 178 ? -99.123  30.419  7.398   1.00 49.94  ? 314 TRP B CA  1 
ATOM 5109 C C   . TRP D 4 178 ? -98.285  31.660  7.657   1.00 52.12  ? 314 TRP B C   1 
ATOM 5110 O O   . TRP D 4 178 ? -97.070  31.577  7.859   1.00 46.09  ? 314 TRP B O   1 
ATOM 5111 C CB  . TRP D 4 178 ? -99.862  29.957  8.662   1.00 57.52  ? 314 TRP B CB  1 
ATOM 5112 C CG  . TRP D 4 178 ? -98.980  29.630  9.826   1.00 51.71  ? 314 TRP B CG  1 
ATOM 5113 C CD1 . TRP D 4 178 ? -98.675  30.444  10.875  1.00 60.87  ? 314 TRP B CD1 1 
ATOM 5114 C CD2 . TRP D 4 178 ? -98.301  28.390  10.069  1.00 57.73  ? 314 TRP B CD2 1 
ATOM 5115 N NE1 . TRP D 4 178 ? -97.844  29.792  11.756  1.00 70.32  ? 314 TRP B NE1 1 
ATOM 5116 C CE2 . TRP D 4 178 ? -97.601  28.529  11.285  1.00 66.83  ? 314 TRP B CE2 1 
ATOM 5117 C CE3 . TRP D 4 178 ? -98.216  27.178  9.377   1.00 57.68  ? 314 TRP B CE3 1 
ATOM 5118 C CZ2 . TRP D 4 178 ? -96.822  27.504  11.822  1.00 59.03  ? 314 TRP B CZ2 1 
ATOM 5119 C CZ3 . TRP D 4 178 ? -97.443  26.161  9.911   1.00 58.93  ? 314 TRP B CZ3 1 
ATOM 5120 C CH2 . TRP D 4 178 ? -96.755  26.331  11.122  1.00 64.60  ? 314 TRP B CH2 1 
ATOM 5121 N N   . LYS D 4 179 ? -98.944  32.814  7.617   1.00 43.25  ? 315 LYS B N   1 
ATOM 5122 C CA  . LYS D 4 179 ? -98.299  34.103  7.812   1.00 44.07  ? 315 LYS B CA  1 
ATOM 5123 C C   . LYS D 4 179 ? -98.815  34.739  9.094   1.00 50.47  ? 315 LYS B C   1 
ATOM 5124 O O   . LYS D 4 179 ? -100.020 34.730  9.359   1.00 60.36  ? 315 LYS B O   1 
ATOM 5125 C CB  . LYS D 4 179 ? -98.559  35.035  6.626   1.00 41.49  ? 315 LYS B CB  1 
ATOM 5126 C CG  . LYS D 4 179 ? -97.728  36.305  6.646   1.00 41.59  ? 315 LYS B CG  1 
ATOM 5127 C CD  . LYS D 4 179 ? -97.901  37.102  5.362   1.00 46.06  ? 315 LYS B CD  1 
ATOM 5128 C CE  . LYS D 4 179 ? -97.148  38.421  5.428   1.00 43.48  ? 315 LYS B CE  1 
ATOM 5129 N NZ  . LYS D 4 179 ? -97.401  39.275  4.240   1.00 55.96  ? 315 LYS B NZ  1 
ATOM 5130 N N   . LEU D 4 180 ? -97.900  35.288  9.887   1.00 42.21  ? 316 LEU B N   1 
ATOM 5131 C CA  . LEU D 4 180 ? -98.234  35.929  11.151  1.00 41.24  ? 316 LEU B CA  1 
ATOM 5132 C C   . LEU D 4 180 ? -98.027  37.431  11.021  1.00 53.15  ? 316 LEU B C   1 
ATOM 5133 O O   . LEU D 4 180 ? -96.915  37.883  10.726  1.00 58.72  ? 316 LEU B O   1 
ATOM 5134 C CB  . LEU D 4 180 ? -97.377  35.368  12.286  1.00 53.07  ? 316 LEU B CB  1 
ATOM 5135 C CG  . LEU D 4 180 ? -97.472  36.093  13.630  1.00 43.08  ? 316 LEU B CG  1 
ATOM 5136 C CD1 . LEU D 4 180 ? -98.883  36.012  14.190  1.00 43.75  ? 316 LEU B CD1 1 
ATOM 5137 C CD2 . LEU D 4 180 ? -96.467  35.514  14.604  1.00 55.45  ? 316 LEU B CD2 1 
ATOM 5138 N N   . HIS D 4 181 ? -99.092  38.198  11.245  1.00 50.00  ? 317 HIS B N   1 
ATOM 5139 C CA  . HIS D 4 181 ? -99.032  39.655  11.274  1.00 53.72  ? 317 HIS B CA  1 
ATOM 5140 C C   . HIS D 4 181 ? -99.173  40.133  12.711  1.00 46.89  ? 317 HIS B C   1 
ATOM 5141 O O   . HIS D 4 181 ? -100.025 39.635  13.454  1.00 48.34  ? 317 HIS B O   1 
ATOM 5142 C CB  . HIS D 4 181 ? -100.127 40.282  10.405  1.00 44.51  ? 317 HIS B CB  1 
ATOM 5143 C CG  . HIS D 4 181 ? -100.277 39.650  9.057   1.00 42.30  ? 317 HIS B CG  1 
ATOM 5144 N ND1 . HIS D 4 181 ? -100.858 38.414  8.871   1.00 55.77  ? 317 HIS B ND1 1 
ATOM 5145 C CD2 . HIS D 4 181 ? -99.937  40.095  7.824   1.00 48.97  ? 317 HIS B CD2 1 
ATOM 5146 C CE1 . HIS D 4 181 ? -100.861 38.120  7.583   1.00 56.18  ? 317 HIS B CE1 1 
ATOM 5147 N NE2 . HIS D 4 181 ? -100.309 39.125  6.925   1.00 60.92  ? 317 HIS B NE2 1 
ATOM 5148 N N   . THR D 4 182 ? -98.336  41.091  13.106  1.00 51.65  ? 318 THR B N   1 
ATOM 5149 C CA  . THR D 4 182 ? -98.360  41.623  14.460  1.00 39.36  ? 318 THR B CA  1 
ATOM 5150 C C   . THR D 4 182 ? -98.419  43.142  14.420  1.00 42.55  ? 318 THR B C   1 
ATOM 5151 O O   . THR D 4 182 ? -97.857  43.782  13.528  1.00 55.24  ? 318 THR B O   1 
ATOM 5152 C CB  . THR D 4 182 ? -97.136  41.188  15.276  1.00 40.60  ? 318 THR B CB  1 
ATOM 5153 O OG1 . THR D 4 182 ? -95.967  41.850  14.780  1.00 50.93  ? 318 THR B OG1 1 
ATOM 5154 C CG2 . THR D 4 182 ? -96.932  39.685  15.175  1.00 42.52  ? 318 THR B CG2 1 
ATOM 5155 N N   . SER D 4 183 ? -99.107  43.713  15.400  1.00 46.83  ? 319 SER B N   1 
ATOM 5156 C CA  . SER D 4 183 ? -99.253  45.151  15.537  1.00 44.59  ? 319 SER B CA  1 
ATOM 5157 C C   . SER D 4 183 ? -99.054  45.502  17.004  1.00 50.70  ? 319 SER B C   1 
ATOM 5158 O O   . SER D 4 183 ? -99.295  44.660  17.880  1.00 46.82  ? 319 SER B O   1 
ATOM 5159 C CB  . SER D 4 183 ? -100.638 45.610  15.049  1.00 50.18  ? 319 SER B CB  1 
ATOM 5160 O OG  . SER D 4 183 ? -100.667 46.994  14.747  1.00 60.76  ? 319 SER B OG  1 
ATOM 5161 N N   . PRO D 4 184 ? -98.587  46.717  17.307  1.00 46.69  ? 320 PRO B N   1 
ATOM 5162 C CA  . PRO D 4 184 ? -98.357  47.078  18.712  1.00 57.57  ? 320 PRO B CA  1 
ATOM 5163 C C   . PRO D 4 184 ? -99.649  47.076  19.513  1.00 40.03  ? 320 PRO B C   1 
ATOM 5164 O O   . PRO D 4 184 ? -100.720 47.425  19.014  1.00 53.49  ? 320 PRO B O   1 
ATOM 5165 C CB  . PRO D 4 184 ? -97.751  48.486  18.631  1.00 49.44  ? 320 PRO B CB  1 
ATOM 5166 C CG  . PRO D 4 184 ? -97.296  48.638  17.221  1.00 54.62  ? 320 PRO B CG  1 
ATOM 5167 C CD  . PRO D 4 184 ? -98.216  47.810  16.395  1.00 47.51  ? 320 PRO B CD  1 
ATOM 5168 N N   . LEU D 4 185 ? -99.529  46.688  20.780  1.00 43.39  ? 321 LEU B N   1 
ATOM 5169 C CA  . LEU D 4 185 ? -100.669 46.568  21.688  1.00 55.78  ? 321 LEU B CA  1 
ATOM 5170 C C   . LEU D 4 185 ? -100.377 47.430  22.916  1.00 45.40  ? 321 LEU B C   1 
ATOM 5171 O O   . LEU D 4 185 ? -99.753  46.963  23.872  1.00 39.10  ? 321 LEU B O   1 
ATOM 5172 C CB  . LEU D 4 185 ? -100.901 45.109  22.058  1.00 45.27  ? 321 LEU B CB  1 
ATOM 5173 C CG  . LEU D 4 185 ? -101.983 44.814  23.087  1.00 54.93  ? 321 LEU B CG  1 
ATOM 5174 C CD1 . LEU D 4 185 ? -103.349 45.120  22.493  1.00 48.84  ? 321 LEU B CD1 1 
ATOM 5175 C CD2 . LEU D 4 185 ? -101.887 43.369  23.536  1.00 53.91  ? 321 LEU B CD2 1 
ATOM 5176 N N   . CYS D 4 186 ? -100.802 48.693  22.878  1.00 44.12  ? 322 CYS B N   1 
ATOM 5177 C CA  . CYS D 4 186 ? -100.622 49.617  23.989  1.00 54.01  ? 322 CYS B CA  1 
ATOM 5178 C C   . CYS D 4 186 ? -101.896 49.726  24.822  1.00 52.91  ? 322 CYS B C   1 
ATOM 5179 O O   . CYS D 4 186 ? -102.956 49.204  24.468  1.00 48.48  ? 322 CYS B O   1 
ATOM 5180 C CB  . CYS D 4 186 ? -100.228 51.017  23.500  1.00 56.79  ? 322 CYS B CB  1 
ATOM 5181 S SG  . CYS D 4 186 ? -98.912  51.156  22.281  1.00 73.79  ? 322 CYS B SG  1 
ATOM 5182 N N   . THR D 4 187 ? -101.774 50.426  25.948  1.00 54.48  ? 323 THR B N   1 
ATOM 5183 C CA  . THR D 4 187 ? -102.947 50.847  26.697  1.00 59.55  ? 323 THR B CA  1 
ATOM 5184 C C   . THR D 4 187 ? -103.579 52.061  26.021  1.00 58.30  ? 323 THR B C   1 
ATOM 5185 O O   . THR D 4 187 ? -102.931 52.797  25.271  1.00 66.17  ? 323 THR B O   1 
ATOM 5186 C CB  . THR D 4 187 ? -102.592 51.170  28.152  1.00 49.20  ? 323 THR B CB  1 
ATOM 5187 O OG1 . THR D 4 187 ? -101.613 52.215  28.194  1.00 57.75  ? 323 THR B OG1 1 
ATOM 5188 C CG2 . THR D 4 187 ? -102.037 49.938  28.849  1.00 39.34  ? 323 THR B CG2 1 
ATOM 5189 N N   . THR D 4 188 ? -104.862 52.271  26.307  1.00 57.92  ? 324 THR B N   1 
ATOM 5190 C CA  . THR D 4 188 ? -105.698 53.166  25.521  1.00 52.15  ? 324 THR B CA  1 
ATOM 5191 C C   . THR D 4 188 ? -105.761 54.587  26.079  1.00 62.26  ? 324 THR B C   1 
ATOM 5192 O O   . THR D 4 188 ? -106.647 55.354  25.686  1.00 58.48  ? 324 THR B O   1 
ATOM 5193 C CB  . THR D 4 188 ? -107.107 52.581  25.405  1.00 52.38  ? 324 THR B CB  1 
ATOM 5194 O OG1 . THR D 4 188 ? -107.659 52.390  26.715  1.00 59.47  ? 324 THR B OG1 1 
ATOM 5195 C CG2 . THR D 4 188 ? -107.062 51.242  24.686  1.00 48.74  ? 324 THR B CG2 1 
ATOM 5196 N N   . ASN D 4 189 ? -104.838 54.962  26.964  1.00 67.95  ? 325 ASN B N   1 
ATOM 5197 C CA  . ASN D 4 189 ? -104.890 56.284  27.576  1.00 65.71  ? 325 ASN B CA  1 
ATOM 5198 C C   . ASN D 4 189 ? -104.700 57.375  26.525  1.00 66.16  ? 325 ASN B C   1 
ATOM 5199 O O   . ASN D 4 189 ? -103.954 57.218  25.555  1.00 68.90  ? 325 ASN B O   1 
ATOM 5200 C CB  . ASN D 4 189 ? -103.826 56.411  28.668  1.00 66.34  ? 325 ASN B CB  1 
ATOM 5201 C CG  . ASN D 4 189 ? -104.063 57.599  29.585  1.00 71.77  ? 325 ASN B CG  1 
ATOM 5202 O OD1 . ASN D 4 189 ? -104.258 58.729  29.131  1.00 55.99  ? 325 ASN B OD1 1 
ATOM 5203 N ND2 . ASN D 4 189 ? -104.045 57.344  30.891  1.00 75.88  ? 325 ASN B ND2 1 
ATOM 5204 N N   . THR D 4 190 ? -105.398 58.493  26.730  1.00 78.53  ? 326 THR B N   1 
ATOM 5205 C CA  . THR D 4 190 ? -105.359 59.606  25.788  1.00 62.74  ? 326 THR B CA  1 
ATOM 5206 C C   . THR D 4 190 ? -104.074 60.418  25.899  1.00 71.89  ? 326 THR B C   1 
ATOM 5207 O O   . THR D 4 190 ? -103.631 61.006  24.906  1.00 73.21  ? 326 THR B O   1 
ATOM 5208 C CB  . THR D 4 190 ? -106.566 60.520  26.009  1.00 79.16  ? 326 THR B CB  1 
ATOM 5209 O OG1 . THR D 4 190 ? -107.739 59.723  26.218  1.00 95.79  ? 326 THR B OG1 1 
ATOM 5210 C CG2 . THR D 4 190 ? -106.787 61.411  24.805  1.00 63.56  ? 326 THR B CG2 1 
ATOM 5211 N N   . LYS D 4 191 ? -103.474 60.477  27.086  1.00 93.12  ? 327 LYS B N   1 
ATOM 5212 C CA  . LYS D 4 191 ? -102.272 61.271  27.291  1.00 91.78  ? 327 LYS B CA  1 
ATOM 5213 C C   . LYS D 4 191 ? -101.070 60.636  26.596  1.00 95.16  ? 327 LYS B C   1 
ATOM 5214 O O   . LYS D 4 191 ? -101.046 59.438  26.299  1.00 106.31 ? 327 LYS B O   1 
ATOM 5215 C CB  . LYS D 4 191 ? -101.985 61.436  28.784  1.00 92.50  ? 327 LYS B CB  1 
ATOM 5216 C CG  . LYS D 4 191 ? -101.761 62.876  29.220  1.00 109.12 ? 327 LYS B CG  1 
ATOM 5217 C CD  . LYS D 4 191 ? -103.069 63.647  29.301  1.00 128.17 ? 327 LYS B CD  1 
ATOM 5218 C CE  . LYS D 4 191 ? -102.871 65.004  29.961  1.00 133.33 ? 327 LYS B CE  1 
ATOM 5219 N NZ  . LYS D 4 191 ? -104.156 65.744  30.107  1.00 130.29 ? 327 LYS B NZ  1 
ATOM 5220 N N   . GLU D 4 192 ? -100.060 61.463  26.337  1.00 97.63  ? 328 GLU B N   1 
ATOM 5221 C CA  . GLU D 4 192 ? -98.844  61.015  25.674  1.00 114.22 ? 328 GLU B CA  1 
ATOM 5222 C C   . GLU D 4 192 ? -97.845  60.509  26.707  1.00 114.19 ? 328 GLU B C   1 
ATOM 5223 O O   . GLU D 4 192 ? -97.752  61.043  27.817  1.00 108.61 ? 328 GLU B O   1 
ATOM 5224 C CB  . GLU D 4 192 ? -98.222  62.145  24.848  1.00 122.40 ? 328 GLU B CB  1 
ATOM 5225 C CG  . GLU D 4 192 ? -97.476  63.206  25.656  1.00 135.18 ? 328 GLU B CG  1 
ATOM 5226 C CD  . GLU D 4 192 ? -98.386  64.039  26.541  1.00 146.53 ? 328 GLU B CD  1 
ATOM 5227 O OE1 . GLU D 4 192 ? -99.617  64.018  26.326  1.00 150.14 ? 328 GLU B OE1 1 
ATOM 5228 O OE2 . GLU D 4 192 ? -97.868  64.712  27.458  1.00 134.10 ? 328 GLU B OE2 1 
ATOM 5229 N N   . GLY D 4 193 ? -97.119  59.454  26.346  1.00 111.01 ? 329 GLY B N   1 
ATOM 5230 C CA  . GLY D 4 193 ? -96.111  58.895  27.221  1.00 114.84 ? 329 GLY B CA  1 
ATOM 5231 C C   . GLY D 4 193 ? -96.636  58.255  28.486  1.00 104.00 ? 329 GLY B C   1 
ATOM 5232 O O   . GLY D 4 193 ? -95.831  57.822  29.319  1.00 122.84 ? 329 GLY B O   1 
ATOM 5233 N N   . SER D 4 194 ? -97.955  58.178  28.660  1.00 76.12  ? 330 SER B N   1 
ATOM 5234 C CA  . SER D 4 194 ? -98.570  57.576  29.836  1.00 66.95  ? 330 SER B CA  1 
ATOM 5235 C C   . SER D 4 194 ? -99.083  56.171  29.556  1.00 70.71  ? 330 SER B C   1 
ATOM 5236 O O   . SER D 4 194 ? -100.051 55.726  30.181  1.00 78.48  ? 330 SER B O   1 
ATOM 5237 C CB  . SER D 4 194 ? -99.706  58.460  30.344  1.00 85.34  ? 330 SER B CB  1 
ATOM 5238 O OG  . SER D 4 194 ? -100.781 58.465  29.423  1.00 77.30  ? 330 SER B OG  1 
ATOM 5239 N N   . ASN D 4 195 ? -98.451  55.466  28.625  1.00 82.01  ? 331 ASN B N   1 
ATOM 5240 C CA  . ASN D 4 195 ? -98.922  54.170  28.170  1.00 62.08  ? 331 ASN B CA  1 
ATOM 5241 C C   . ASN D 4 195 ? -97.781  53.166  28.191  1.00 58.41  ? 331 ASN B C   1 
ATOM 5242 O O   . ASN D 4 195 ? -96.616  53.517  27.985  1.00 66.75  ? 331 ASN B O   1 
ATOM 5243 C CB  . ASN D 4 195 ? -99.505  54.264  26.758  1.00 70.72  ? 331 ASN B CB  1 
ATOM 5244 C CG  . ASN D 4 195 ? -100.909 54.818  26.750  1.00 68.31  ? 331 ASN B CG  1 
ATOM 5245 O OD1 . ASN D 4 195 ? -101.752 54.405  27.544  1.00 58.84  ? 331 ASN B OD1 1 
ATOM 5246 N ND2 . ASN D 4 195 ? -101.163 55.776  25.868  1.00 80.68  ? 331 ASN B ND2 1 
ATOM 5247 N N   . ILE D 4 196 ? -98.133  51.912  28.454  1.00 47.76  ? 332 ILE B N   1 
ATOM 5248 C CA  . ILE D 4 196 ? -97.220  50.786  28.318  1.00 52.49  ? 332 ILE B CA  1 
ATOM 5249 C C   . ILE D 4 196 ? -97.662  49.970  27.112  1.00 59.97  ? 332 ILE B C   1 
ATOM 5250 O O   . ILE D 4 196 ? -98.862  49.759  26.898  1.00 46.43  ? 332 ILE B O   1 
ATOM 5251 C CB  . ILE D 4 196 ? -97.171  49.921  29.594  1.00 45.15  ? 332 ILE B CB  1 
ATOM 5252 C CG1 . ILE D 4 196 ? -98.562  49.399  29.957  1.00 40.06  ? 332 ILE B CG1 1 
ATOM 5253 C CG2 . ILE D 4 196 ? -96.567  50.706  30.742  1.00 56.01  ? 332 ILE B CG2 1 
ATOM 5254 C CD1 . ILE D 4 196 ? -98.534  48.224  30.909  1.00 51.83  ? 332 ILE B CD1 1 
ATOM 5255 N N   . CYS D 4 197 ? -96.698  49.539  26.306  1.00 55.10  ? 333 CYS B N   1 
ATOM 5256 C CA  . CYS D 4 197 ? -97.010  48.881  25.049  1.00 53.54  ? 333 CYS B CA  1 
ATOM 5257 C C   . CYS D 4 197 ? -96.209  47.596  24.901  1.00 45.02  ? 333 CYS B C   1 
ATOM 5258 O O   . CYS D 4 197 ? -95.099  47.468  25.426  1.00 37.14  ? 333 CYS B O   1 
ATOM 5259 C CB  . CYS D 4 197 ? -96.742  49.804  23.861  1.00 42.79  ? 333 CYS B CB  1 
ATOM 5260 S SG  . CYS D 4 197 ? -97.816  49.462  22.481  1.00 96.31  ? 333 CYS B SG  1 
ATOM 5261 N N   . LEU D 4 198 ? -96.793  46.647  24.169  1.00 38.82  ? 334 LEU B N   1 
ATOM 5262 C CA  . LEU D 4 198 ? -96.189  45.348  23.912  1.00 48.38  ? 334 LEU B CA  1 
ATOM 5263 C C   . LEU D 4 198 ? -96.483  44.952  22.468  1.00 58.21  ? 334 LEU B C   1 
ATOM 5264 O O   . LEU D 4 198 ? -97.535  45.293  21.922  1.00 56.06  ? 334 LEU B O   1 
ATOM 5265 C CB  . LEU D 4 198 ? -96.717  44.303  24.914  1.00 35.83  ? 334 LEU B CB  1 
ATOM 5266 C CG  . LEU D 4 198 ? -96.457  42.795  24.827  1.00 62.36  ? 334 LEU B CG  1 
ATOM 5267 C CD1 . LEU D 4 198 ? -96.711  42.181  26.196  1.00 61.45  ? 334 LEU B CD1 1 
ATOM 5268 C CD2 . LEU D 4 198 ? -97.352  42.115  23.802  1.00 61.24  ? 334 LEU B CD2 1 
ATOM 5269 N N   . THR D 4 199 ? -95.544  44.235  21.849  1.00 52.56  ? 335 THR B N   1 
ATOM 5270 C CA  . THR D 4 199 ? -95.696  43.829  20.454  1.00 53.00  ? 335 THR B CA  1 
ATOM 5271 C C   . THR D 4 199 ? -95.036  42.479  20.224  1.00 54.52  ? 335 THR B C   1 
ATOM 5272 O O   . THR D 4 199 ? -93.886  42.275  20.623  1.00 53.50  ? 335 THR B O   1 
ATOM 5273 C CB  . THR D 4 199 ? -95.083  44.859  19.496  1.00 54.52  ? 335 THR B CB  1 
ATOM 5274 O OG1 . THR D 4 199 ? -95.441  46.183  19.910  1.00 84.61  ? 335 THR B OG1 1 
ATOM 5275 C CG2 . THR D 4 199 ? -95.577  44.623  18.073  1.00 47.14  ? 335 THR B CG2 1 
ATOM 5276 N N   . ARG D 4 200 ? -95.753  41.573  19.560  1.00 47.34  ? 336 ARG B N   1 
ATOM 5277 C CA  . ARG D 4 200 ? -95.159  40.305  19.158  1.00 52.68  ? 336 ARG B CA  1 
ATOM 5278 C C   . ARG D 4 200 ? -94.155  40.537  18.035  1.00 56.22  ? 336 ARG B C   1 
ATOM 5279 O O   . ARG D 4 200 ? -94.456  41.213  17.048  1.00 56.47  ? 336 ARG B O   1 
ATOM 5280 C CB  . ARG D 4 200 ? -96.242  39.325  18.710  1.00 48.36  ? 336 ARG B CB  1 
ATOM 5281 C CG  . ARG D 4 200 ? -97.274  39.015  19.777  1.00 47.71  ? 336 ARG B CG  1 
ATOM 5282 C CD  . ARG D 4 200 ? -98.215  37.911  19.328  1.00 56.88  ? 336 ARG B CD  1 
ATOM 5283 N NE  . ARG D 4 200 ? -97.497  36.747  18.821  1.00 68.12  ? 336 ARG B NE  1 
ATOM 5284 C CZ  . ARG D 4 200 ? -98.073  35.720  18.212  1.00 60.10  ? 336 ARG B CZ  1 
ATOM 5285 N NH1 . ARG D 4 200 ? -99.382  35.672  18.026  1.00 55.30  ? 336 ARG B NH1 1 
ATOM 5286 N NH2 . ARG D 4 200 ? -97.317  34.715  17.779  1.00 62.45  ? 336 ARG B NH2 1 
ATOM 5287 N N   . THR D 4 201 ? -92.956  39.977  18.188  1.00 53.19  ? 337 THR B N   1 
ATOM 5288 C CA  . THR D 4 201 ? -91.862  40.217  17.256  1.00 64.71  ? 337 THR B CA  1 
ATOM 5289 C C   . THR D 4 201 ? -91.613  39.049  16.311  1.00 67.93  ? 337 THR B C   1 
ATOM 5290 O O   . THR D 4 201 ? -90.655  39.091  15.532  1.00 75.89  ? 337 THR B O   1 
ATOM 5291 C CB  . THR D 4 201 ? -90.582  40.555  18.027  1.00 54.41  ? 337 THR B CB  1 
ATOM 5292 O OG1 . THR D 4 201 ? -90.346  39.560  19.032  1.00 55.68  ? 337 THR B OG1 1 
ATOM 5293 C CG2 . THR D 4 201 ? -90.691  41.928  18.674  1.00 48.61  ? 337 THR B CG2 1 
ATOM 5294 N N   . ASP D 4 202 ? -92.461  38.021  16.337  1.00 59.46  ? 338 ASP B N   1 
ATOM 5295 C CA  . ASP D 4 202 ? -92.254  36.816  15.541  1.00 75.02  ? 338 ASP B CA  1 
ATOM 5296 C C   . ASP D 4 202 ? -93.027  36.839  14.222  1.00 63.84  ? 338 ASP B C   1 
ATOM 5297 O O   . ASP D 4 202 ? -93.321  35.778  13.658  1.00 54.93  ? 338 ASP B O   1 
ATOM 5298 C CB  . ASP D 4 202 ? -92.632  35.580  16.355  1.00 71.14  ? 338 ASP B CB  1 
ATOM 5299 C CG  . ASP D 4 202 ? -93.869  35.798  17.199  1.00 65.87  ? 338 ASP B CG  1 
ATOM 5300 O OD1 . ASP D 4 202 ? -94.311  36.960  17.315  1.00 67.06  ? 338 ASP B OD1 1 
ATOM 5301 O OD2 . ASP D 4 202 ? -94.409  34.809  17.735  1.00 86.89  ? 338 ASP B OD2 1 
ATOM 5302 N N   . ARG D 4 203 ? -93.358  38.024  13.716  1.00 59.42  ? 339 ARG B N   1 
ATOM 5303 C CA  . ARG D 4 203 ? -94.099  38.125  12.465  1.00 61.64  ? 339 ARG B CA  1 
ATOM 5304 C C   . ARG D 4 203 ? -93.258  37.612  11.298  1.00 53.57  ? 339 ARG B C   1 
ATOM 5305 O O   . ARG D 4 203 ? -92.031  37.743  11.282  1.00 61.88  ? 339 ARG B O   1 
ATOM 5306 C CB  . ARG D 4 203 ? -94.518  39.574  12.206  1.00 40.74  ? 339 ARG B CB  1 
ATOM 5307 C CG  . ARG D 4 203 ? -93.350  40.543  12.116  1.00 56.29  ? 339 ARG B CG  1 
ATOM 5308 C CD  . ARG D 4 203 ? -93.763  41.906  11.582  1.00 59.44  ? 339 ARG B CD  1 
ATOM 5309 N NE  . ARG D 4 203 ? -93.983  42.885  12.639  1.00 73.16  ? 339 ARG B NE  1 
ATOM 5310 C CZ  . ARG D 4 203 ? -94.942  43.801  12.627  1.00 84.80  ? 339 ARG B CZ  1 
ATOM 5311 N NH1 . ARG D 4 203 ? -95.793  43.897  11.618  1.00 82.92  ? 339 ARG B NH1 1 
ATOM 5312 N NH2 . ARG D 4 203 ? -95.051  44.639  13.653  1.00 83.45  ? 339 ARG B NH2 1 
ATOM 5313 N N   . GLY D 4 204 ? -93.928  37.026  10.317  1.00 47.02  ? 340 GLY B N   1 
ATOM 5314 C CA  . GLY D 4 204 ? -93.257  36.497  9.145   1.00 46.86  ? 340 GLY B CA  1 
ATOM 5315 C C   . GLY D 4 204 ? -93.993  35.285  8.607   1.00 40.77  ? 340 GLY B C   1 
ATOM 5316 O O   . GLY D 4 204 ? -95.170  35.084  8.888   1.00 52.09  ? 340 GLY B O   1 
ATOM 5317 N N   . TRP D 4 205 ? -93.276  34.484  7.827   1.00 46.37  ? 341 TRP B N   1 
ATOM 5318 C CA  . TRP D 4 205 ? -93.826  33.270  7.240   1.00 43.82  ? 341 TRP B CA  1 
ATOM 5319 C C   . TRP D 4 205 ? -93.375  32.050  8.030   1.00 43.81  ? 341 TRP B C   1 
ATOM 5320 O O   . TRP D 4 205 ? -92.241  31.991  8.514   1.00 54.66  ? 341 TRP B O   1 
ATOM 5321 C CB  . TRP D 4 205 ? -93.415  33.120  5.771   1.00 47.67  ? 341 TRP B CB  1 
ATOM 5322 C CG  . TRP D 4 205 ? -94.263  33.925  4.824   1.00 43.16  ? 341 TRP B CG  1 
ATOM 5323 C CD1 . TRP D 4 205 ? -93.933  35.106  4.230   1.00 46.86  ? 341 TRP B CD1 1 
ATOM 5324 C CD2 . TRP D 4 205 ? -95.591  33.610  4.380   1.00 44.94  ? 341 TRP B CD2 1 
ATOM 5325 N NE1 . TRP D 4 205 ? -94.967  35.541  3.436   1.00 61.37  ? 341 TRP B NE1 1 
ATOM 5326 C CE2 . TRP D 4 205 ? -95.998  34.642  3.514   1.00 45.67  ? 341 TRP B CE2 1 
ATOM 5327 C CE3 . TRP D 4 205 ? -96.474  32.555  4.632   1.00 46.61  ? 341 TRP B CE3 1 
ATOM 5328 C CZ2 . TRP D 4 205 ? -97.248  34.652  2.897   1.00 48.51  ? 341 TRP B CZ2 1 
ATOM 5329 C CZ3 . TRP D 4 205 ? -97.716  32.566  4.019   1.00 45.21  ? 341 TRP B CZ3 1 
ATOM 5330 C CH2 . TRP D 4 205 ? -98.091  33.608  3.163   1.00 46.07  ? 341 TRP B CH2 1 
ATOM 5331 N N   . TYR D 4 206 ? -94.276  31.083  8.166   1.00 45.66  ? 342 TYR B N   1 
ATOM 5332 C CA  . TYR D 4 206 ? -93.986  29.821  8.826   1.00 42.01  ? 342 TYR B CA  1 
ATOM 5333 C C   . TYR D 4 206 ? -94.406  28.683  7.911   1.00 52.87  ? 342 TYR B C   1 
ATOM 5334 O O   . TYR D 4 206 ? -95.481  28.729  7.307   1.00 49.60  ? 342 TYR B O   1 
ATOM 5335 C CB  . TYR D 4 206 ? -94.721  29.702  10.161  1.00 45.45  ? 342 TYR B CB  1 
ATOM 5336 C CG  . TYR D 4 206 ? -94.280  30.686  11.219  1.00 58.65  ? 342 TYR B CG  1 
ATOM 5337 C CD1 . TYR D 4 206 ? -94.665  32.018  11.162  1.00 51.14  ? 342 TYR B CD1 1 
ATOM 5338 C CD2 . TYR D 4 206 ? -93.495  30.275  12.288  1.00 57.00  ? 342 TYR B CD2 1 
ATOM 5339 C CE1 . TYR D 4 206 ? -94.266  32.915  12.127  1.00 46.90  ? 342 TYR B CE1 1 
ATOM 5340 C CE2 . TYR D 4 206 ? -93.093  31.164  13.259  1.00 50.95  ? 342 TYR B CE2 1 
ATOM 5341 C CZ  . TYR D 4 206 ? -93.482  32.483  13.175  1.00 56.34  ? 342 TYR B CZ  1 
ATOM 5342 O OH  . TYR D 4 206 ? -93.080  33.372  14.145  1.00 61.91  ? 342 TYR B OH  1 
ATOM 5343 N N   . CYS D 4 207 ? -93.558  27.664  7.809   1.00 50.11  ? 343 CYS B N   1 
ATOM 5344 C CA  . CYS D 4 207 ? -93.847  26.517  6.963   1.00 52.07  ? 343 CYS B CA  1 
ATOM 5345 C C   . CYS D 4 207 ? -93.351  25.251  7.641   1.00 58.62  ? 343 CYS B C   1 
ATOM 5346 O O   . CYS D 4 207 ? -92.279  25.244  8.253   1.00 56.91  ? 343 CYS B O   1 
ATOM 5347 C CB  . CYS D 4 207 ? -93.202  26.663  5.573   1.00 61.51  ? 343 CYS B CB  1 
ATOM 5348 S SG  . CYS D 4 207 ? -93.871  28.014  4.560   1.00 88.80  ? 343 CYS B SG  1 
ATOM 5349 N N   . ASP D 4 208 ? -94.143  24.187  7.535   1.00 56.92  ? 344 ASP B N   1 
ATOM 5350 C CA  . ASP D 4 208 ? -93.756  22.896  8.087   1.00 47.60  ? 344 ASP B CA  1 
ATOM 5351 C C   . ASP D 4 208 ? -92.657  22.266  7.238   1.00 46.34  ? 344 ASP B C   1 
ATOM 5352 O O   . ASP D 4 208 ? -92.739  22.239  6.008   1.00 60.31  ? 344 ASP B O   1 
ATOM 5353 C CB  . ASP D 4 208 ? -94.967  21.970  8.149   1.00 54.62  ? 344 ASP B CB  1 
ATOM 5354 C CG  . ASP D 4 208 ? -95.848  22.249  9.345   1.00 61.74  ? 344 ASP B CG  1 
ATOM 5355 O OD1 . ASP D 4 208 ? -95.301  22.474  10.444  1.00 77.49  ? 344 ASP B OD1 1 
ATOM 5356 O OD2 . ASP D 4 208 ? -97.088  22.254  9.184   1.00 65.96  ? 344 ASP B OD2 1 
ATOM 5357 N N   . ASN D 4 209 ? -91.625  21.749  7.902   1.00 48.78  ? 345 ASN B N   1 
ATOM 5358 C CA  . ASN D 4 209 ? -90.469  21.212  7.187   1.00 56.56  ? 345 ASN B CA  1 
ATOM 5359 C C   . ASN D 4 209 ? -89.780  20.183  8.077   1.00 67.59  ? 345 ASN B C   1 
ATOM 5360 O O   . ASN D 4 209 ? -89.216  20.544  9.115   1.00 57.18  ? 345 ASN B O   1 
ATOM 5361 C CB  . ASN D 4 209 ? -89.511  22.336  6.804   1.00 43.66  ? 345 ASN B CB  1 
ATOM 5362 C CG  . ASN D 4 209 ? -88.461  21.896  5.803   1.00 51.62  ? 345 ASN B CG  1 
ATOM 5363 O OD1 . ASN D 4 209 ? -88.229  20.702  5.609   1.00 53.55  ? 345 ASN B OD1 1 
ATOM 5364 N ND2 . ASN D 4 209 ? -87.800  22.866  5.178   1.00 46.14  ? 345 ASN B ND2 1 
ATOM 5365 N N   . ALA D 4 210 ? -89.822  18.912  7.662   1.00 62.64  ? 346 ALA B N   1 
ATOM 5366 C CA  . ALA D 4 210 ? -89.077  17.826  8.310   1.00 47.97  ? 346 ALA B CA  1 
ATOM 5367 C C   . ALA D 4 210 ? -89.379  17.730  9.804   1.00 62.02  ? 346 ALA B C   1 
ATOM 5368 O O   . ALA D 4 210 ? -88.483  17.519  10.624  1.00 75.59  ? 346 ALA B O   1 
ATOM 5369 C CB  . ALA D 4 210 ? -87.571  17.974  8.076   1.00 47.60  ? 346 ALA B CB  1 
ATOM 5370 N N   . GLY D 4 211 ? -90.651  17.878  10.166  1.00 58.55  ? 347 GLY B N   1 
ATOM 5371 C CA  . GLY D 4 211 ? -91.041  17.805  11.558  1.00 63.75  ? 347 GLY B CA  1 
ATOM 5372 C C   . GLY D 4 211 ? -90.767  19.055  12.364  1.00 53.00  ? 347 GLY B C   1 
ATOM 5373 O O   . GLY D 4 211 ? -91.060  19.073  13.566  1.00 73.84  ? 347 GLY B O   1 
ATOM 5374 N N   . SER D 4 212 ? -90.217  20.092  11.745  1.00 55.38  ? 348 SER B N   1 
ATOM 5375 C CA  . SER D 4 212 ? -89.953  21.377  12.374  1.00 42.96  ? 348 SER B CA  1 
ATOM 5376 C C   . SER D 4 212 ? -90.748  22.452  11.638  1.00 61.59  ? 348 SER B C   1 
ATOM 5377 O O   . SER D 4 212 ? -91.575  22.160  10.769  1.00 65.03  ? 348 SER B O   1 
ATOM 5378 C CB  . SER D 4 212 ? -88.455  21.691  12.363  1.00 41.20  ? 348 SER B CB  1 
ATOM 5379 O OG  . SER D 4 212 ? -87.694  20.580  12.792  1.00 64.62  ? 348 SER B OG  1 
ATOM 5380 N N   . VAL D 4 213 ? -90.489  23.708  11.988  1.00 49.77  ? 349 VAL B N   1 
ATOM 5381 C CA  . VAL D 4 213 ? -91.095  24.853  11.321  1.00 44.85  ? 349 VAL B CA  1 
ATOM 5382 C C   . VAL D 4 213 ? -89.972  25.759  10.839  1.00 51.74  ? 349 VAL B C   1 
ATOM 5383 O O   . VAL D 4 213 ? -89.162  26.234  11.643  1.00 56.88  ? 349 VAL B O   1 
ATOM 5384 C CB  . VAL D 4 213 ? -92.059  25.610  12.247  1.00 48.01  ? 349 VAL B CB  1 
ATOM 5385 C CG1 . VAL D 4 213 ? -92.686  26.785  11.517  1.00 50.94  ? 349 VAL B CG1 1 
ATOM 5386 C CG2 . VAL D 4 213 ? -93.136  24.671  12.770  1.00 62.49  ? 349 VAL B CG2 1 
ATOM 5387 N N   . SER D 4 214 ? -89.913  25.989  9.530   1.00 58.25  ? 350 SER B N   1 
ATOM 5388 C CA  . SER D 4 214 ? -88.986  26.958  8.962   1.00 45.14  ? 350 SER B CA  1 
ATOM 5389 C C   . SER D 4 214 ? -89.640  28.332  9.020   1.00 48.90  ? 350 SER B C   1 
ATOM 5390 O O   . SER D 4 214 ? -90.734  28.530  8.480   1.00 44.04  ? 350 SER B O   1 
ATOM 5391 C CB  . SER D 4 214 ? -88.605  26.587  7.531   1.00 43.08  ? 350 SER B CB  1 
ATOM 5392 O OG  . SER D 4 214 ? -87.791  25.428  7.510   1.00 47.87  ? 350 SER B OG  1 
ATOM 5393 N N   . PHE D 4 215 ? -88.986  29.265  9.700   1.00 55.37  ? 351 PHE B N   1 
ATOM 5394 C CA  . PHE D 4 215 ? -89.550  30.575  9.981   1.00 50.82  ? 351 PHE B CA  1 
ATOM 5395 C C   . PHE D 4 215 ? -88.762  31.628  9.216   1.00 48.93  ? 351 PHE B C   1 
ATOM 5396 O O   . PHE D 4 215 ? -87.535  31.707  9.337   1.00 50.06  ? 351 PHE B O   1 
ATOM 5397 C CB  . PHE D 4 215 ? -89.530  30.854  11.488  1.00 49.24  ? 351 PHE B CB  1 
ATOM 5398 C CG  . PHE D 4 215 ? -89.611  32.310  11.846  1.00 52.90  ? 351 PHE B CG  1 
ATOM 5399 C CD1 . PHE D 4 215 ? -90.749  33.045  11.557  1.00 56.56  ? 351 PHE B CD1 1 
ATOM 5400 C CD2 . PHE D 4 215 ? -88.559  32.939  12.489  1.00 50.79  ? 351 PHE B CD2 1 
ATOM 5401 C CE1 . PHE D 4 215 ? -90.833  34.383  11.894  1.00 52.51  ? 351 PHE B CE1 1 
ATOM 5402 C CE2 . PHE D 4 215 ? -88.636  34.277  12.828  1.00 54.73  ? 351 PHE B CE2 1 
ATOM 5403 C CZ  . PHE D 4 215 ? -89.775  34.999  12.531  1.00 53.13  ? 351 PHE B CZ  1 
ATOM 5404 N N   . PHE D 4 216 ? -89.471  32.433  8.433   1.00 48.32  ? 352 PHE B N   1 
ATOM 5405 C CA  . PHE D 4 216 ? -88.851  33.464  7.609   1.00 57.24  ? 352 PHE B CA  1 
ATOM 5406 C C   . PHE D 4 216 ? -89.250  34.829  8.151   1.00 67.95  ? 352 PHE B C   1 
ATOM 5407 O O   . PHE D 4 216 ? -90.346  35.323  7.842   1.00 60.99  ? 352 PHE B O   1 
ATOM 5408 C CB  . PHE D 4 216 ? -89.279  33.310  6.145   1.00 54.89  ? 352 PHE B CB  1 
ATOM 5409 C CG  . PHE D 4 216 ? -89.173  31.898  5.629   1.00 42.02  ? 352 PHE B CG  1 
ATOM 5410 C CD1 . PHE D 4 216 ? -90.223  31.006  5.779   1.00 46.68  ? 352 PHE B CD1 1 
ATOM 5411 C CD2 . PHE D 4 216 ? -88.021  31.464  4.994   1.00 45.84  ? 352 PHE B CD2 1 
ATOM 5412 C CE1 . PHE D 4 216 ? -90.123  29.706  5.314   1.00 39.22  ? 352 PHE B CE1 1 
ATOM 5413 C CE2 . PHE D 4 216 ? -87.918  30.167  4.521   1.00 45.80  ? 352 PHE B CE2 1 
ATOM 5414 C CZ  . PHE D 4 216 ? -88.970  29.287  4.685   1.00 43.95  ? 352 PHE B CZ  1 
ATOM 5415 N N   . PRO D 4 217 ? -88.404  35.476  8.962   1.00 76.26  ? 353 PRO B N   1 
ATOM 5416 C CA  . PRO D 4 217 ? -88.819  36.753  9.568   1.00 61.32  ? 353 PRO B CA  1 
ATOM 5417 C C   . PRO D 4 217 ? -88.981  37.877  8.562   1.00 65.27  ? 353 PRO B C   1 
ATOM 5418 O O   . PRO D 4 217 ? -89.950  38.642  8.652   1.00 69.96  ? 353 PRO B O   1 
ATOM 5419 C CB  . PRO D 4 217 ? -87.702  37.044  10.580  1.00 59.12  ? 353 PRO B CB  1 
ATOM 5420 C CG  . PRO D 4 217 ? -86.524  36.266  10.113  1.00 60.99  ? 353 PRO B CG  1 
ATOM 5421 C CD  . PRO D 4 217 ? -87.011  35.116  9.283   1.00 66.52  ? 353 PRO B CD  1 
ATOM 5422 N N   . GLN D 4 218 ? -88.062  38.008  7.609   1.00 54.11  ? 354 GLN B N   1 
ATOM 5423 C CA  . GLN D 4 218 ? -88.181  39.028  6.571   1.00 74.87  ? 354 GLN B CA  1 
ATOM 5424 C C   . GLN D 4 218 ? -89.079  38.470  5.473   1.00 86.10  ? 354 GLN B C   1 
ATOM 5425 O O   . GLN D 4 218 ? -88.620  37.842  4.517   1.00 97.91  ? 354 GLN B O   1 
ATOM 5426 C CB  . GLN D 4 218 ? -86.808  39.429  6.045   1.00 75.34  ? 354 GLN B CB  1 
ATOM 5427 C CG  . GLN D 4 218 ? -85.794  38.299  6.048   1.00 92.38  ? 354 GLN B CG  1 
ATOM 5428 C CD  . GLN D 4 218 ? -84.363  38.798  6.003   1.00 99.78  ? 354 GLN B CD  1 
ATOM 5429 O OE1 . GLN D 4 218 ? -84.034  39.831  6.588   1.00 98.21  ? 354 GLN B OE1 1 
ATOM 5430 N NE2 . GLN D 4 218 ? -83.503  38.064  5.305   1.00 93.74  ? 354 GLN B NE2 1 
ATOM 5431 N N   . ALA D 4 219 ? -90.385  38.709  5.617   1.00 75.25  ? 355 ALA B N   1 
ATOM 5432 C CA  . ALA D 4 219 ? -91.372  38.174  4.686   1.00 86.23  ? 355 ALA B CA  1 
ATOM 5433 C C   . ALA D 4 219 ? -91.267  38.791  3.298   1.00 106.38 ? 355 ALA B C   1 
ATOM 5434 O O   . ALA D 4 219 ? -91.925  38.307  2.371   1.00 89.54  ? 355 ALA B O   1 
ATOM 5435 C CB  . ALA D 4 219 ? -92.783  38.380  5.242   1.00 65.76  ? 355 ALA B CB  1 
ATOM 5436 N N   . GLU D 4 220 ? -90.468  39.846  3.140   1.00 103.00 ? 356 GLU B N   1 
ATOM 5437 C CA  . GLU D 4 220 ? -90.247  40.476  1.848   1.00 88.61  ? 356 GLU B CA  1 
ATOM 5438 C C   . GLU D 4 220 ? -89.336  39.659  0.940   1.00 83.40  ? 356 GLU B C   1 
ATOM 5439 O O   . GLU D 4 220 ? -89.224  39.980  -0.248  1.00 121.73 ? 356 GLU B O   1 
ATOM 5440 C CB  . GLU D 4 220 ? -89.656  41.875  2.046   1.00 108.22 ? 356 GLU B CB  1 
ATOM 5441 C CG  . GLU D 4 220 ? -90.423  42.748  3.038   1.00 108.00 ? 356 GLU B CG  1 
ATOM 5442 C CD  . GLU D 4 220 ? -90.003  42.513  4.481   1.00 115.52 ? 356 GLU B CD  1 
ATOM 5443 O OE1 . GLU D 4 220 ? -88.785  42.535  4.760   1.00 115.16 ? 356 GLU B OE1 1 
ATOM 5444 O OE2 . GLU D 4 220 ? -90.890  42.301  5.334   1.00 124.60 ? 356 GLU B OE2 1 
ATOM 5445 N N   . THR D 4 221 ? -88.684  38.623  1.465   1.00 80.14  ? 357 THR B N   1 
ATOM 5446 C CA  . THR D 4 221 ? -87.871  37.715  0.667   1.00 86.04  ? 357 THR B CA  1 
ATOM 5447 C C   . THR D 4 221 ? -88.669  36.485  0.238   1.00 90.28  ? 357 THR B C   1 
ATOM 5448 O O   . THR D 4 221 ? -88.121  35.579  -0.399  1.00 103.07 ? 357 THR B O   1 
ATOM 5449 C CB  . THR D 4 221 ? -86.618  37.306  1.454   1.00 113.56 ? 357 THR B CB  1 
ATOM 5450 O OG1 . THR D 4 221 ? -86.031  38.471  2.044   1.00 124.93 ? 357 THR B OG1 1 
ATOM 5451 C CG2 . THR D 4 221 ? -85.565  36.694  0.533   1.00 97.24  ? 357 THR B CG2 1 
ATOM 5452 N N   . CYS D 4 222 ? -89.957  36.442  0.564   1.00 86.74  ? 358 CYS B N   1 
ATOM 5453 C CA  . CYS D 4 222 ? -90.835  35.344  0.185   1.00 79.37  ? 358 CYS B CA  1 
ATOM 5454 C C   . CYS D 4 222 ? -91.837  35.850  -0.845  1.00 68.98  ? 358 CYS B C   1 
ATOM 5455 O O   . CYS D 4 222 ? -92.489  36.877  -0.632  1.00 81.90  ? 358 CYS B O   1 
ATOM 5456 C CB  . CYS D 4 222 ? -91.560  34.769  1.406   1.00 55.14  ? 358 CYS B CB  1 
ATOM 5457 S SG  . CYS D 4 222 ? -90.544  33.685  2.458   1.00 63.00  ? 358 CYS B SG  1 
ATOM 5458 N N   . LYS D 4 223 ? -91.949  35.136  -1.960  1.00 59.81  ? 359 LYS B N   1 
ATOM 5459 C CA  . LYS D 4 223 ? -92.828  35.512  -3.058  1.00 68.74  ? 359 LYS B CA  1 
ATOM 5460 C C   . LYS D 4 223 ? -94.050  34.608  -3.058  1.00 54.68  ? 359 LYS B C   1 
ATOM 5461 O O   . LYS D 4 223 ? -93.921  33.382  -2.980  1.00 58.51  ? 359 LYS B O   1 
ATOM 5462 C CB  . LYS D 4 223 ? -92.090  35.424  -4.396  1.00 58.50  ? 359 LYS B CB  1 
ATOM 5463 C CG  . LYS D 4 223 ? -90.783  36.197  -4.403  1.00 62.61  ? 359 LYS B CG  1 
ATOM 5464 C CD  . LYS D 4 223 ? -89.709  35.483  -5.194  1.00 67.12  ? 359 LYS B CD  1 
ATOM 5465 C CE  . LYS D 4 223 ? -88.405  36.267  -5.167  1.00 72.86  ? 359 LYS B CE  1 
ATOM 5466 N NZ  . LYS D 4 223 ? -88.633  37.733  -5.301  1.00 72.38  ? 359 LYS B NZ  1 
ATOM 5467 N N   . VAL D 4 224 ? -95.230  35.213  -3.149  1.00 56.51  ? 360 VAL B N   1 
ATOM 5468 C CA  . VAL D 4 224 ? -96.496  34.497  -3.058  1.00 51.46  ? 360 VAL B CA  1 
ATOM 5469 C C   . VAL D 4 224 ? -97.141  34.478  -4.437  1.00 59.47  ? 360 VAL B C   1 
ATOM 5470 O O   . VAL D 4 224 ? -97.343  35.532  -5.054  1.00 73.65  ? 360 VAL B O   1 
ATOM 5471 C CB  . VAL D 4 224 ? -97.433  35.133  -2.019  1.00 50.18  ? 360 VAL B CB  1 
ATOM 5472 C CG1 . VAL D 4 224 ? -98.682  34.284  -1.845  1.00 55.33  ? 360 VAL B CG1 1 
ATOM 5473 C CG2 . VAL D 4 224 ? -96.711  35.315  -0.695  1.00 56.57  ? 360 VAL B CG2 1 
ATOM 5474 N N   . GLN D 4 225 ? -97.458  33.280  -4.919  1.00 75.07  ? 361 GLN B N   1 
ATOM 5475 C CA  . GLN D 4 225 ? -98.213  33.078  -6.154  1.00 64.57  ? 361 GLN B CA  1 
ATOM 5476 C C   . GLN D 4 225 ? -99.532  32.416  -5.767  1.00 71.97  ? 361 GLN B C   1 
ATOM 5477 O O   . GLN D 4 225 ? -99.580  31.201  -5.551  1.00 68.22  ? 361 GLN B O   1 
ATOM 5478 C CB  . GLN D 4 225 ? -97.429  32.227  -7.152  1.00 79.79  ? 361 GLN B CB  1 
ATOM 5479 C CG  . GLN D 4 225 ? -96.320  32.966  -7.897  1.00 86.48  ? 361 GLN B CG  1 
ATOM 5480 C CD  . GLN D 4 225 ? -96.764  34.303  -8.463  1.00 96.39  ? 361 GLN B CD  1 
ATOM 5481 O OE1 . GLN D 4 225 ? -96.033  35.292  -8.389  1.00 100.53 ? 361 GLN B OE1 1 
ATOM 5482 N NE2 . GLN D 4 225 ? -97.954  34.333  -9.057  1.00 100.89 ? 361 GLN B NE2 1 
ATOM 5483 N N   . SER D 4 226 ? -100.593 33.222  -5.676  1.00 76.90  ? 362 SER B N   1 
ATOM 5484 C CA  . SER D 4 226 ? -101.909 32.758  -5.248  1.00 78.58  ? 362 SER B CA  1 
ATOM 5485 C C   . SER D 4 226 ? -101.844 32.123  -3.863  1.00 85.52  ? 362 SER B C   1 
ATOM 5486 O O   . SER D 4 226 ? -101.742 32.828  -2.854  1.00 83.39  ? 362 SER B O   1 
ATOM 5487 C CB  . SER D 4 226 ? -102.493 31.770  -6.263  1.00 75.81  ? 362 SER B CB  1 
ATOM 5488 O OG  . SER D 4 226 ? -103.808 31.383  -5.904  1.00 89.13  ? 362 SER B OG  1 
ATOM 5489 N N   . ASN D 4 227 ? -101.907 30.795  -3.804  1.00 79.36  ? 363 ASN B N   1 
ATOM 5490 C CA  . ASN D 4 227 ? -101.840 30.066  -2.546  1.00 65.33  ? 363 ASN B CA  1 
ATOM 5491 C C   . ASN D 4 227 ? -100.461 29.484  -2.271  1.00 64.51  ? 363 ASN B C   1 
ATOM 5492 O O   . ASN D 4 227 ? -100.274 28.830  -1.240  1.00 62.38  ? 363 ASN B O   1 
ATOM 5493 C CB  . ASN D 4 227 ? -102.885 28.944  -2.528  1.00 72.22  ? 363 ASN B CB  1 
ATOM 5494 C CG  . ASN D 4 227 ? -102.759 28.009  -3.718  1.00 92.75  ? 363 ASN B CG  1 
ATOM 5495 O OD1 . ASN D 4 227 ? -102.197 28.373  -4.752  1.00 98.07  ? 363 ASN B OD1 1 
ATOM 5496 N ND2 . ASN D 4 227 ? -103.288 26.798  -3.578  1.00 92.52  ? 363 ASN B ND2 1 
ATOM 5497 N N   . ARG D 4 228 ? -99.494  29.704  -3.157  1.00 65.40  ? 364 ARG B N   1 
ATOM 5498 C CA  . ARG D 4 228 ? -98.162  29.137  -3.006  1.00 67.23  ? 364 ARG B CA  1 
ATOM 5499 C C   . ARG D 4 228 ? -97.192  30.185  -2.479  1.00 61.07  ? 364 ARG B C   1 
ATOM 5500 O O   . ARG D 4 228 ? -97.274  31.363  -2.838  1.00 57.41  ? 364 ARG B O   1 
ATOM 5501 C CB  . ARG D 4 228 ? -97.645  28.577  -4.331  1.00 61.34  ? 364 ARG B CB  1 
ATOM 5502 C CG  . ARG D 4 228 ? -96.447  27.665  -4.158  1.00 55.69  ? 364 ARG B CG  1 
ATOM 5503 C CD  . ARG D 4 228 ? -96.498  26.481  -5.098  1.00 59.36  ? 364 ARG B CD  1 
ATOM 5504 N NE  . ARG D 4 228 ? -97.094  25.298  -4.491  1.00 54.19  ? 364 ARG B NE  1 
ATOM 5505 C CZ  . ARG D 4 228 ? -98.173  24.686  -4.958  1.00 80.46  ? 364 ARG B CZ  1 
ATOM 5506 N NH1 . ARG D 4 228 ? -98.813  25.132  -6.028  1.00 78.84  ? 364 ARG B NH1 1 
ATOM 5507 N NH2 . ARG D 4 228 ? -98.619  23.596  -4.340  1.00 85.83  ? 364 ARG B NH2 1 
ATOM 5508 N N   . VAL D 4 229 ? -96.275  29.748  -1.623  1.00 55.56  ? 365 VAL B N   1 
ATOM 5509 C CA  . VAL D 4 229 ? -95.270  30.618  -1.027  1.00 55.75  ? 365 VAL B CA  1 
ATOM 5510 C C   . VAL D 4 229 ? -93.898  30.093  -1.426  1.00 55.52  ? 365 VAL B C   1 
ATOM 5511 O O   . VAL D 4 229 ? -93.580  28.922  -1.185  1.00 53.41  ? 365 VAL B O   1 
ATOM 5512 C CB  . VAL D 4 229 ? -95.415  30.689  0.501   1.00 48.86  ? 365 VAL B CB  1 
ATOM 5513 C CG1 . VAL D 4 229 ? -94.489  31.740  1.074   1.00 50.59  ? 365 VAL B CG1 1 
ATOM 5514 C CG2 . VAL D 4 229 ? -96.854  31.000  0.874   1.00 52.43  ? 365 VAL B CG2 1 
ATOM 5515 N N   . PHE D 4 230 ? -93.095  30.954  -2.043  1.00 58.31  ? 366 PHE B N   1 
ATOM 5516 C CA  . PHE D 4 230 ? -91.732  30.628  -2.440  1.00 53.53  ? 366 PHE B CA  1 
ATOM 5517 C C   . PHE D 4 230 ? -90.780  31.322  -1.477  1.00 53.16  ? 366 PHE B C   1 
ATOM 5518 O O   . PHE D 4 230 ? -90.806  32.550  -1.352  1.00 57.87  ? 366 PHE B O   1 
ATOM 5519 C CB  . PHE D 4 230 ? -91.460  31.055  -3.884  1.00 44.72  ? 366 PHE B CB  1 
ATOM 5520 C CG  . PHE D 4 230 ? -92.193  30.234  -4.913  1.00 46.19  ? 366 PHE B CG  1 
ATOM 5521 C CD1 . PHE D 4 230 ? -93.508  30.521  -5.245  1.00 49.76  ? 366 PHE B CD1 1 
ATOM 5522 C CD2 . PHE D 4 230 ? -91.558  29.184  -5.561  1.00 55.00  ? 366 PHE B CD2 1 
ATOM 5523 C CE1 . PHE D 4 230 ? -94.182  29.770  -6.193  1.00 51.60  ? 366 PHE B CE1 1 
ATOM 5524 C CE2 . PHE D 4 230 ? -92.227  28.428  -6.514  1.00 49.28  ? 366 PHE B CE2 1 
ATOM 5525 C CZ  . PHE D 4 230 ? -93.541  28.722  -6.828  1.00 48.70  ? 366 PHE B CZ  1 
ATOM 5526 N N   . CYS D 4 231 ? -89.951  30.537  -0.793  1.00 60.99  ? 367 CYS B N   1 
ATOM 5527 C CA  . CYS D 4 231 ? -89.056  31.067  0.223   1.00 57.80  ? 367 CYS B CA  1 
ATOM 5528 C C   . CYS D 4 231 ? -87.693  30.400  0.098   1.00 54.07  ? 367 CYS B C   1 
ATOM 5529 O O   . CYS D 4 231 ? -87.567  29.280  -0.403  1.00 60.89  ? 367 CYS B O   1 
ATOM 5530 C CB  . CYS D 4 231 ? -89.622  30.861  1.638   1.00 49.94  ? 367 CYS B CB  1 
ATOM 5531 S SG  . CYS D 4 231 ? -91.145  31.784  2.026   1.00 72.82  ? 367 CYS B SG  1 
ATOM 5532 N N   . ASP D 4 232 ? -86.672  31.114  0.560   1.00 50.38  ? 368 ASP B N   1 
ATOM 5533 C CA  . ASP D 4 232 ? -85.298  30.629  0.589   1.00 51.53  ? 368 ASP B CA  1 
ATOM 5534 C C   . ASP D 4 232 ? -84.956  30.199  2.011   1.00 60.34  ? 368 ASP B C   1 
ATOM 5535 O O   . ASP D 4 232 ? -85.119  30.980  2.954   1.00 60.75  ? 368 ASP B O   1 
ATOM 5536 C CB  . ASP D 4 232 ? -84.339  31.723  0.112   1.00 53.63  ? 368 ASP B CB  1 
ATOM 5537 C CG  . ASP D 4 232 ? -82.971  31.190  -0.264  1.00 64.20  ? 368 ASP B CG  1 
ATOM 5538 O OD1 . ASP D 4 232 ? -82.405  30.389  0.510   1.00 74.20  ? 368 ASP B OD1 1 
ATOM 5539 O OD2 . ASP D 4 232 ? -82.454  31.576  -1.335  1.00 65.32  ? 368 ASP B OD2 1 
ATOM 5540 N N   . THR D 4 233 ? -84.490  28.955  2.166   1.00 64.61  ? 369 THR B N   1 
ATOM 5541 C CA  . THR D 4 233 ? -84.153  28.466  3.501   1.00 55.04  ? 369 THR B CA  1 
ATOM 5542 C C   . THR D 4 233 ? -82.912  29.141  4.069   1.00 54.25  ? 369 THR B C   1 
ATOM 5543 O O   . THR D 4 233 ? -82.731  29.140  5.291   1.00 60.54  ? 369 THR B O   1 
ATOM 5544 C CB  . THR D 4 233 ? -83.948  26.948  3.496   1.00 50.70  ? 369 THR B CB  1 
ATOM 5545 O OG1 . THR D 4 233 ? -82.812  26.612  2.690   1.00 64.70  ? 369 THR B OG1 1 
ATOM 5546 C CG2 . THR D 4 233 ? -85.181  26.241  2.954   1.00 47.60  ? 369 THR B CG2 1 
ATOM 5547 N N   . MET D 4 234 ? -82.059  29.719  3.218   1.00 62.77  ? 370 MET B N   1 
ATOM 5548 C CA  . MET D 4 234 ? -80.894  30.448  3.709   1.00 68.69  ? 370 MET B CA  1 
ATOM 5549 C C   . MET D 4 234 ? -81.298  31.683  4.507   1.00 74.90  ? 370 MET B C   1 
ATOM 5550 O O   . MET D 4 234 ? -80.483  32.215  5.269   1.00 83.91  ? 370 MET B O   1 
ATOM 5551 C CB  . MET D 4 234 ? -79.995  30.843  2.533   1.00 67.70  ? 370 MET B CB  1 
ATOM 5552 C CG  . MET D 4 234 ? -78.600  31.330  2.911   1.00 74.36  ? 370 MET B CG  1 
ATOM 5553 S SD  . MET D 4 234 ? -77.758  32.165  1.536   1.00 115.32 ? 370 MET B SD  1 
ATOM 5554 C CE  . MET D 4 234 ? -77.858  30.931  0.237   1.00 58.79  ? 370 MET B CE  1 
ATOM 5555 N N   . ASN D 4 235 ? -82.538  32.141  4.353   1.00 78.67  ? 371 ASN B N   1 
ATOM 5556 C CA  . ASN D 4 235 ? -83.090  33.260  5.109   1.00 64.49  ? 371 ASN B CA  1 
ATOM 5557 C C   . ASN D 4 235 ? -84.142  32.780  6.103   1.00 53.66  ? 371 ASN B C   1 
ATOM 5558 O O   . ASN D 4 235 ? -85.164  33.436  6.318   1.00 60.22  ? 371 ASN B O   1 
ATOM 5559 C CB  . ASN D 4 235 ? -83.690  34.304  4.169   1.00 68.48  ? 371 ASN B CB  1 
ATOM 5560 C CG  . ASN D 4 235 ? -82.635  35.044  3.370   1.00 83.35  ? 371 ASN B CG  1 
ATOM 5561 O OD1 . ASN D 4 235 ? -81.448  34.730  3.446   1.00 102.72 ? 371 ASN B OD1 1 
ATOM 5562 N ND2 . ASN D 4 235 ? -83.066  36.032  2.596   1.00 99.90  ? 371 ASN B ND2 1 
ATOM 5563 N N   . SER D 4 236 ? -83.904  31.623  6.719   1.00 56.10  ? 372 SER B N   1 
ATOM 5564 C CA  . SER D 4 236 ? -84.883  30.991  7.589   1.00 61.39  ? 372 SER B CA  1 
ATOM 5565 C C   . SER D 4 236 ? -84.245  30.578  8.907   1.00 56.11  ? 372 SER B C   1 
ATOM 5566 O O   . SER D 4 236 ? -83.030  30.384  9.009   1.00 58.02  ? 372 SER B O   1 
ATOM 5567 C CB  . SER D 4 236 ? -85.511  29.755  6.934   1.00 54.98  ? 372 SER B CB  1 
ATOM 5568 O OG  . SER D 4 236 ? -84.555  28.720  6.794   1.00 58.76  ? 372 SER B OG  1 
ATOM 5569 N N   . LEU D 4 237 ? -85.096  30.438  9.916   1.00 50.69  ? 373 LEU B N   1 
ATOM 5570 C CA  . LEU D 4 237 ? -84.727  29.874  11.202  1.00 61.60  ? 373 LEU B CA  1 
ATOM 5571 C C   . LEU D 4 237 ? -85.557  28.618  11.427  1.00 56.46  ? 373 LEU B C   1 
ATOM 5572 O O   . LEU D 4 237 ? -86.751  28.591  11.113  1.00 59.08  ? 373 LEU B O   1 
ATOM 5573 C CB  . LEU D 4 237 ? -84.960  30.882  12.336  1.00 58.59  ? 373 LEU B CB  1 
ATOM 5574 C CG  . LEU D 4 237 ? -83.892  31.966  12.495  1.00 57.08  ? 373 LEU B CG  1 
ATOM 5575 C CD1 . LEU D 4 237 ? -84.128  32.775  13.755  1.00 58.12  ? 373 LEU B CD1 1 
ATOM 5576 C CD2 . LEU D 4 237 ? -82.494  31.361  12.492  1.00 71.86  ? 373 LEU B CD2 1 
ATOM 5577 N N   . THR D 4 238 ? -84.922  27.578  11.956  1.00 62.21  ? 374 THR B N   1 
ATOM 5578 C CA  . THR D 4 238 ? -85.599  26.314  12.223  1.00 58.02  ? 374 THR B CA  1 
ATOM 5579 C C   . THR D 4 238 ? -86.082  26.308  13.669  1.00 55.52  ? 374 THR B C   1 
ATOM 5580 O O   . THR D 4 238 ? -85.284  26.489  14.594  1.00 53.90  ? 374 THR B O   1 
ATOM 5581 C CB  . THR D 4 238 ? -84.669  25.133  11.957  1.00 48.77  ? 374 THR B CB  1 
ATOM 5582 O OG1 . THR D 4 238 ? -83.883  24.875  13.127  1.00 97.10  ? 374 THR B OG1 1 
ATOM 5583 C CG2 . THR D 4 238 ? -83.737  25.451  10.797  1.00 44.56  ? 374 THR B CG2 1 
ATOM 5584 N N   . LEU D 4 239 ? -87.380  26.094  13.859  1.00 49.81  ? 375 LEU B N   1 
ATOM 5585 C CA  . LEU D 4 239 ? -88.022  26.174  15.160  1.00 53.80  ? 375 LEU B CA  1 
ATOM 5586 C C   . LEU D 4 239 ? -88.834  24.918  15.435  1.00 62.17  ? 375 LEU B C   1 
ATOM 5587 O O   . LEU D 4 239 ? -89.280  24.245  14.500  1.00 60.95  ? 375 LEU B O   1 
ATOM 5588 C CB  . LEU D 4 239 ? -88.945  27.400  15.242  1.00 55.55  ? 375 LEU B CB  1 
ATOM 5589 C CG  . LEU D 4 239 ? -88.331  28.766  14.931  1.00 52.25  ? 375 LEU B CG  1 
ATOM 5590 C CD1 . LEU D 4 239 ? -89.354  29.863  15.158  1.00 47.93  ? 375 LEU B CD1 1 
ATOM 5591 C CD2 . LEU D 4 239 ? -87.092  29.007  15.778  1.00 56.83  ? 375 LEU B CD2 1 
ATOM 5592 N N   . PRO D 4 240 ? -89.033  24.573  16.708  1.00 67.24  ? 376 PRO B N   1 
ATOM 5593 C CA  . PRO D 4 240 ? -89.911  23.446  17.040  1.00 52.84  ? 376 PRO B CA  1 
ATOM 5594 C C   . PRO D 4 240 ? -91.362  23.760  16.714  1.00 63.89  ? 376 PRO B C   1 
ATOM 5595 O O   . PRO D 4 240 ? -91.784  24.918  16.671  1.00 67.72  ? 376 PRO B O   1 
ATOM 5596 C CB  . PRO D 4 240 ? -89.713  23.271  18.550  1.00 57.43  ? 376 PRO B CB  1 
ATOM 5597 C CG  . PRO D 4 240 ? -88.429  23.969  18.858  1.00 62.69  ? 376 PRO B CG  1 
ATOM 5598 C CD  . PRO D 4 240 ? -88.366  25.115  17.903  1.00 51.87  ? 376 PRO B CD  1 
ATOM 5599 N N   . SER D 4 241 ? -92.137  22.693  16.500  1.00 70.93  ? 377 SER B N   1 
ATOM 5600 C CA  . SER D 4 241 ? -93.543  22.854  16.144  1.00 61.35  ? 377 SER B CA  1 
ATOM 5601 C C   . SER D 4 241 ? -94.327  23.611  17.205  1.00 71.41  ? 377 SER B C   1 
ATOM 5602 O O   . SER D 4 241 ? -95.364  24.205  16.887  1.00 72.94  ? 377 SER B O   1 
ATOM 5603 C CB  . SER D 4 241 ? -94.187  21.487  15.907  1.00 61.00  ? 377 SER B CB  1 
ATOM 5604 O OG  . SER D 4 241 ? -93.489  20.762  14.911  1.00 77.74  ? 377 SER B OG  1 
ATOM 5605 N N   . GLU D 4 242 ? -93.848  23.623  18.451  1.00 83.35  ? 378 GLU B N   1 
ATOM 5606 C CA  . GLU D 4 242 ? -94.521  24.328  19.536  1.00 79.36  ? 378 GLU B CA  1 
ATOM 5607 C C   . GLU D 4 242 ? -94.502  25.842  19.370  1.00 76.50  ? 378 GLU B C   1 
ATOM 5608 O O   . GLU D 4 242 ? -95.075  26.540  20.213  1.00 84.74  ? 378 GLU B O   1 
ATOM 5609 C CB  . GLU D 4 242 ? -93.892  23.954  20.881  1.00 69.70  ? 378 GLU B CB  1 
ATOM 5610 C CG  . GLU D 4 242 ? -94.179  22.530  21.334  1.00 80.64  ? 378 GLU B CG  1 
ATOM 5611 C CD  . GLU D 4 242 ? -93.368  21.497  20.577  1.00 95.10  ? 378 GLU B CD  1 
ATOM 5612 O OE1 . GLU D 4 242 ? -92.317  21.864  20.008  1.00 81.79  ? 378 GLU B OE1 1 
ATOM 5613 O OE2 . GLU D 4 242 ? -93.786  20.319  20.549  1.00 105.58 ? 378 GLU B OE2 1 
ATOM 5614 N N   . VAL D 4 243 ? -93.857  26.370  18.327  1.00 75.83  ? 379 VAL B N   1 
ATOM 5615 C CA  . VAL D 4 243 ? -93.906  27.809  18.096  1.00 60.40  ? 379 VAL B CA  1 
ATOM 5616 C C   . VAL D 4 243 ? -95.315  28.242  17.713  1.00 64.02  ? 379 VAL B C   1 
ATOM 5617 O O   . VAL D 4 243 ? -95.695  29.400  17.926  1.00 74.43  ? 379 VAL B O   1 
ATOM 5618 C CB  . VAL D 4 243 ? -92.871  28.218  17.032  1.00 62.37  ? 379 VAL B CB  1 
ATOM 5619 C CG1 . VAL D 4 243 ? -93.302  27.747  15.647  1.00 65.76  ? 379 VAL B CG1 1 
ATOM 5620 C CG2 . VAL D 4 243 ? -92.656  29.721  17.054  1.00 52.71  ? 379 VAL B CG2 1 
ATOM 5621 N N   . ASN D 4 244 ? -96.115  27.329  17.154  1.00 69.46  ? 380 ASN B N   1 
ATOM 5622 C CA  . ASN D 4 244 ? -97.512  27.630  16.867  1.00 66.10  ? 380 ASN B CA  1 
ATOM 5623 C C   . ASN D 4 244 ? -98.345  27.792  18.133  1.00 76.80  ? 380 ASN B C   1 
ATOM 5624 O O   . ASN D 4 244 ? -99.453  28.333  18.065  1.00 79.43  ? 380 ASN B O   1 
ATOM 5625 C CB  . ASN D 4 244 ? -98.115  26.539  15.982  1.00 61.87  ? 380 ASN B CB  1 
ATOM 5626 C CG  . ASN D 4 244 ? -99.228  27.057  15.096  1.00 90.39  ? 380 ASN B CG  1 
ATOM 5627 O OD1 . ASN D 4 244 ? -99.785  28.127  15.341  1.00 84.18  ? 380 ASN B OD1 1 
ATOM 5628 N ND2 . ASN D 4 244 ? -99.553  26.303  14.051  1.00 113.27 ? 380 ASN B ND2 1 
ATOM 5629 N N   . LEU D 4 245 ? -97.841  27.334  19.283  1.00 72.19  ? 381 LEU B N   1 
ATOM 5630 C CA  . LEU D 4 245 ? -98.567  27.513  20.535  1.00 72.85  ? 381 LEU B CA  1 
ATOM 5631 C C   . LEU D 4 245 ? -98.699  28.981  20.914  1.00 69.06  ? 381 LEU B C   1 
ATOM 5632 O O   . LEU D 4 245 ? -99.627  29.340  21.647  1.00 77.62  ? 381 LEU B O   1 
ATOM 5633 C CB  . LEU D 4 245 ? -97.875  26.744  21.662  1.00 76.36  ? 381 LEU B CB  1 
ATOM 5634 C CG  . LEU D 4 245 ? -98.143  25.240  21.757  1.00 73.25  ? 381 LEU B CG  1 
ATOM 5635 C CD1 . LEU D 4 245 ? -97.702  24.717  23.111  1.00 80.26  ? 381 LEU B CD1 1 
ATOM 5636 C CD2 . LEU D 4 245 ? -99.613  24.928  21.512  1.00 75.38  ? 381 LEU B CD2 1 
ATOM 5637 N N   . CYS D 4 246 ? -97.800  29.838  20.426  1.00 61.18  ? 382 CYS B N   1 
ATOM 5638 C CA  . CYS D 4 246 ? -97.897  31.268  20.689  1.00 63.19  ? 382 CYS B CA  1 
ATOM 5639 C C   . CYS D 4 246 ? -99.136  31.895  20.065  1.00 60.21  ? 382 CYS B C   1 
ATOM 5640 O O   . CYS D 4 246 ? -99.481  33.029  20.414  1.00 63.09  ? 382 CYS B O   1 
ATOM 5641 C CB  . CYS D 4 246 ? -96.645  31.981  20.174  1.00 56.71  ? 382 CYS B CB  1 
ATOM 5642 S SG  . CYS D 4 246 ? -95.164  31.673  21.155  1.00 82.43  ? 382 CYS B SG  1 
ATOM 5643 N N   . ASN D 4 247 ? -99.803  31.196  19.151  1.00 65.13  ? 383 ASN B N   1 
ATOM 5644 C CA  . ASN D 4 247 ? -101.011 31.712  18.528  1.00 74.04  ? 383 ASN B CA  1 
ATOM 5645 C C   . ASN D 4 247 ? -102.277 31.295  19.258  1.00 75.35  ? 383 ASN B C   1 
ATOM 5646 O O   . ASN D 4 247 ? -103.312 31.953  19.102  1.00 74.64  ? 383 ASN B O   1 
ATOM 5647 C CB  . ASN D 4 247 ? -101.086 31.246  17.072  1.00 62.40  ? 383 ASN B CB  1 
ATOM 5648 C CG  . ASN D 4 247 ? -99.912  31.724  16.255  1.00 57.53  ? 383 ASN B CG  1 
ATOM 5649 O OD1 . ASN D 4 247 ? -99.400  32.822  16.470  1.00 54.95  ? 383 ASN B OD1 1 
ATOM 5650 N ND2 . ASN D 4 247 ? -99.470  30.898  15.314  1.00 79.96  ? 383 ASN B ND2 1 
ATOM 5651 N N   . VAL D 4 248 ? -102.222 30.225  20.049  1.00 72.95  ? 384 VAL B N   1 
ATOM 5652 C CA  . VAL D 4 248 ? -103.394 29.758  20.779  1.00 82.70  ? 384 VAL B CA  1 
ATOM 5653 C C   . VAL D 4 248 ? -103.314 30.246  22.220  1.00 73.87  ? 384 VAL B C   1 
ATOM 5654 O O   . VAL D 4 248 ? -104.341 30.512  22.853  1.00 91.04  ? 384 VAL B O   1 
ATOM 5655 C CB  . VAL D 4 248 ? -103.526 28.224  20.704  1.00 77.14  ? 384 VAL B CB  1 
ATOM 5656 C CG1 . VAL D 4 248 ? -103.808 27.790  19.272  1.00 84.34  ? 384 VAL B CG1 1 
ATOM 5657 C CG2 . VAL D 4 248 ? -102.268 27.546  21.219  1.00 71.01  ? 384 VAL B CG2 1 
ATOM 5658 N N   . ASP D 4 249 ? -102.096 30.381  22.741  1.00 72.63  ? 385 ASP B N   1 
ATOM 5659 C CA  . ASP D 4 249 ? -101.904 30.840  24.116  1.00 77.47  ? 385 ASP B CA  1 
ATOM 5660 C C   . ASP D 4 249 ? -100.501 31.422  24.224  1.00 82.51  ? 385 ASP B C   1 
ATOM 5661 O O   . ASP D 4 249 ? -99.520  30.672  24.223  1.00 87.59  ? 385 ASP B O   1 
ATOM 5662 C CB  . ASP D 4 249 ? -102.103 29.695  25.102  1.00 81.78  ? 385 ASP B CB  1 
ATOM 5663 C CG  . ASP D 4 249 ? -102.156 30.166  26.543  1.00 98.22  ? 385 ASP B CG  1 
ATOM 5664 O OD1 . ASP D 4 249 ? -102.023 31.386  26.786  1.00 91.42  ? 385 ASP B OD1 1 
ATOM 5665 O OD2 . ASP D 4 249 ? -102.326 29.310  27.437  1.00 113.00 ? 385 ASP B OD2 1 
ATOM 5666 N N   . ILE D 4 250 ? -100.409 32.750  24.332  1.00 81.29  ? 386 ILE B N   1 
ATOM 5667 C CA  . ILE D 4 250 ? -99.104  33.396  24.389  1.00 74.79  ? 386 ILE B CA  1 
ATOM 5668 C C   . ILE D 4 250 ? -98.396  33.126  25.710  1.00 62.17  ? 386 ILE B C   1 
ATOM 5669 O O   . ILE D 4 250 ? -97.184  33.345  25.816  1.00 76.79  ? 386 ILE B O   1 
ATOM 5670 C CB  . ILE D 4 250 ? -99.241  34.911  24.149  1.00 84.34  ? 386 ILE B CB  1 
ATOM 5671 C CG1 . ILE D 4 250 ? -97.929  35.485  23.602  1.00 68.03  ? 386 ILE B CG1 1 
ATOM 5672 C CG2 . ILE D 4 250 ? -99.635  35.621  25.440  1.00 61.42  ? 386 ILE B CG2 1 
ATOM 5673 C CD1 . ILE D 4 250 ? -98.023  36.926  23.152  1.00 62.03  ? 386 ILE B CD1 1 
ATOM 5674 N N   . PHE D 4 251 ? -99.113  32.649  26.724  1.00 72.93  ? 387 PHE B N   1 
ATOM 5675 C CA  . PHE D 4 251 ? -98.526  32.405  28.034  1.00 90.75  ? 387 PHE B CA  1 
ATOM 5676 C C   . PHE D 4 251 ? -98.183  30.938  28.259  1.00 89.27  ? 387 PHE B C   1 
ATOM 5677 O O   . PHE D 4 251 ? -97.888  30.548  29.393  1.00 88.72  ? 387 PHE B O   1 
ATOM 5678 C CB  . PHE D 4 251 ? -99.464  32.909  29.133  1.00 54.28  ? 387 PHE B CB  1 
ATOM 5679 C CG  . PHE D 4 251 ? -99.572  34.405  29.193  1.00 48.60  ? 387 PHE B CG  1 
ATOM 5680 C CD1 . PHE D 4 251 ? -98.445  35.186  29.385  1.00 47.30  ? 387 PHE B CD1 1 
ATOM 5681 C CD2 . PHE D 4 251 ? -100.800 35.032  29.058  1.00 52.74  ? 387 PHE B CD2 1 
ATOM 5682 C CE1 . PHE D 4 251 ? -98.539  36.566  29.439  1.00 53.37  ? 387 PHE B CE1 1 
ATOM 5683 C CE2 . PHE D 4 251 ? -100.902 36.411  29.112  1.00 46.49  ? 387 PHE B CE2 1 
ATOM 5684 C CZ  . PHE D 4 251 ? -99.769  37.180  29.301  1.00 43.34  ? 387 PHE B CZ  1 
ATOM 5685 N N   . ASN D 4 252 ? -98.208  30.124  27.207  1.00 98.44  ? 388 ASN B N   1 
ATOM 5686 C CA  . ASN D 4 252 ? -97.885  28.712  27.343  1.00 97.90  ? 388 ASN B CA  1 
ATOM 5687 C C   . ASN D 4 252 ? -96.424  28.542  27.756  1.00 99.65  ? 388 ASN B C   1 
ATOM 5688 O O   . ASN D 4 252 ? -95.558  29.302  27.310  1.00 107.87 ? 388 ASN B O   1 
ATOM 5689 C CB  . ASN D 4 252 ? -98.147  27.978  26.029  1.00 110.52 ? 388 ASN B CB  1 
ATOM 5690 C CG  . ASN D 4 252 ? -98.559  26.534  26.238  1.00 124.16 ? 388 ASN B CG  1 
ATOM 5691 O OD1 . ASN D 4 252 ? -97.716  25.639  26.311  1.00 122.97 ? 388 ASN B OD1 1 
ATOM 5692 N ND2 . ASN D 4 252 ? -99.864  26.300  26.332  1.00 126.23 ? 388 ASN B ND2 1 
ATOM 5693 N N   . PRO D 4 253 ? -96.118  27.563  28.613  1.00 99.48  ? 389 PRO B N   1 
ATOM 5694 C CA  . PRO D 4 253 ? -94.728  27.364  29.045  1.00 104.63 ? 389 PRO B CA  1 
ATOM 5695 C C   . PRO D 4 253 ? -93.897  26.500  28.110  1.00 98.32  ? 389 PRO B C   1 
ATOM 5696 O O   . PRO D 4 253 ? -92.672  26.436  28.285  1.00 97.59  ? 389 PRO B O   1 
ATOM 5697 C CB  . PRO D 4 253 ? -94.893  26.687  30.409  1.00 101.87 ? 389 PRO B CB  1 
ATOM 5698 C CG  . PRO D 4 253 ? -96.142  25.882  30.248  1.00 110.14 ? 389 PRO B CG  1 
ATOM 5699 C CD  . PRO D 4 253 ? -97.051  26.682  29.337  1.00 101.35 ? 389 PRO B CD  1 
ATOM 5700 N N   . LYS D 4 254 ? -94.515  25.835  27.130  1.00 98.10  ? 390 LYS B N   1 
ATOM 5701 C CA  . LYS D 4 254 ? -93.776  24.955  26.233  1.00 99.20  ? 390 LYS B CA  1 
ATOM 5702 C C   . LYS D 4 254 ? -92.949  25.713  25.201  1.00 87.72  ? 390 LYS B C   1 
ATOM 5703 O O   . LYS D 4 254 ? -91.998  25.144  24.654  1.00 84.80  ? 390 LYS B O   1 
ATOM 5704 C CB  . LYS D 4 254 ? -94.739  23.995  25.529  1.00 89.42  ? 390 LYS B CB  1 
ATOM 5705 C CG  . LYS D 4 254 ? -95.234  22.868  26.423  1.00 90.07  ? 390 LYS B CG  1 
ATOM 5706 C CD  . LYS D 4 254 ? -95.444  21.575  25.648  1.00 106.37 ? 390 LYS B CD  1 
ATOM 5707 C CE  . LYS D 4 254 ? -96.628  21.674  24.701  1.00 92.89  ? 390 LYS B CE  1 
ATOM 5708 N NZ  . LYS D 4 254 ? -96.855  20.395  23.975  1.00 81.68  ? 390 LYS B NZ  1 
ATOM 5709 N N   . TYR D 4 255 ? -93.284  26.972  24.919  1.00 85.65  ? 391 TYR B N   1 
ATOM 5710 C CA  . TYR D 4 255 ? -92.487  27.811  24.035  1.00 90.73  ? 391 TYR B CA  1 
ATOM 5711 C C   . TYR D 4 255 ? -92.487  29.235  24.569  1.00 72.83  ? 391 TYR B C   1 
ATOM 5712 O O   . TYR D 4 255 ? -93.537  29.764  24.945  1.00 76.64  ? 391 TYR B O   1 
ATOM 5713 C CB  . TYR D 4 255 ? -93.017  27.791  22.591  1.00 82.73  ? 391 TYR B CB  1 
ATOM 5714 C CG  . TYR D 4 255 ? -92.056  28.388  21.583  1.00 70.26  ? 391 TYR B CG  1 
ATOM 5715 C CD1 . TYR D 4 255 ? -92.023  29.757  21.351  1.00 70.48  ? 391 TYR B CD1 1 
ATOM 5716 C CD2 . TYR D 4 255 ? -91.182  27.582  20.867  1.00 74.84  ? 391 TYR B CD2 1 
ATOM 5717 C CE1 . TYR D 4 255 ? -91.144  30.307  20.438  1.00 71.33  ? 391 TYR B CE1 1 
ATOM 5718 C CE2 . TYR D 4 255 ? -90.299  28.123  19.948  1.00 78.44  ? 391 TYR B CE2 1 
ATOM 5719 C CZ  . TYR D 4 255 ? -90.286  29.487  19.737  1.00 86.09  ? 391 TYR B CZ  1 
ATOM 5720 O OH  . TYR D 4 255 ? -89.411  30.034  18.825  1.00 84.85  ? 391 TYR B OH  1 
ATOM 5721 N N   . ASP D 4 256 ? -91.309  29.857  24.587  1.00 77.01  ? 392 ASP B N   1 
ATOM 5722 C CA  . ASP D 4 256 ? -91.147  31.214  25.108  1.00 84.81  ? 392 ASP B CA  1 
ATOM 5723 C C   . ASP D 4 256 ? -91.401  32.201  23.974  1.00 75.55  ? 392 ASP B C   1 
ATOM 5724 O O   . ASP D 4 256 ? -90.522  32.454  23.144  1.00 70.61  ? 392 ASP B O   1 
ATOM 5725 C CB  . ASP D 4 256 ? -89.757  31.393  25.708  1.00 92.47  ? 392 ASP B CB  1 
ATOM 5726 C CG  . ASP D 4 256 ? -89.651  32.631  26.578  1.00 86.52  ? 392 ASP B CG  1 
ATOM 5727 O OD1 . ASP D 4 256 ? -90.703  33.194  26.949  1.00 87.85  ? 392 ASP B OD1 1 
ATOM 5728 O OD2 . ASP D 4 256 ? -88.512  33.040  26.891  1.00 91.24  ? 392 ASP B OD2 1 
ATOM 5729 N N   . CYS D 4 257 ? -92.604  32.770  23.947  1.00 68.49  ? 393 CYS B N   1 
ATOM 5730 C CA  . CYS D 4 257 ? -93.001  33.665  22.868  1.00 68.78  ? 393 CYS B CA  1 
ATOM 5731 C C   . CYS D 4 257 ? -92.181  34.951  22.884  1.00 73.95  ? 393 CYS B C   1 
ATOM 5732 O O   . CYS D 4 257 ? -91.808  35.466  23.939  1.00 74.27  ? 393 CYS B O   1 
ATOM 5733 C CB  . CYS D 4 257 ? -94.490  33.992  22.967  1.00 60.81  ? 393 CYS B CB  1 
ATOM 5734 S SG  . CYS D 4 257 ? -95.559  32.541  22.951  1.00 103.91 ? 393 CYS B SG  1 
ATOM 5735 N N   . LYS D 4 258 ? -91.913  35.471  21.688  1.00 71.39  ? 394 LYS B N   1 
ATOM 5736 C CA  . LYS D 4 258 ? -91.066  36.643  21.518  1.00 61.32  ? 394 LYS B CA  1 
ATOM 5737 C C   . LYS D 4 258 ? -91.913  37.907  21.448  1.00 67.96  ? 394 LYS B C   1 
ATOM 5738 O O   . LYS D 4 258 ? -92.848  37.993  20.645  1.00 65.39  ? 394 LYS B O   1 
ATOM 5739 C CB  . LYS D 4 258 ? -90.215  36.498  20.256  1.00 69.28  ? 394 LYS B CB  1 
ATOM 5740 C CG  . LYS D 4 258 ? -89.242  35.329  20.301  1.00 68.74  ? 394 LYS B CG  1 
ATOM 5741 C CD  . LYS D 4 258 ? -87.995  35.697  21.086  1.00 67.08  ? 394 LYS B CD  1 
ATOM 5742 C CE  . LYS D 4 258 ? -87.491  37.067  20.661  1.00 84.07  ? 394 LYS B CE  1 
ATOM 5743 N NZ  . LYS D 4 258 ? -86.345  37.540  21.482  1.00 90.58  ? 394 LYS B NZ  1 
ATOM 5744 N N   . ILE D 4 259 ? -91.588  38.882  22.300  1.00 68.91  ? 395 ILE B N   1 
ATOM 5745 C CA  . ILE D 4 259 ? -92.272  40.168  22.343  1.00 54.63  ? 395 ILE B CA  1 
ATOM 5746 C C   . ILE D 4 259 ? -91.233  41.270  22.504  1.00 49.68  ? 395 ILE B C   1 
ATOM 5747 O O   . ILE D 4 259 ? -90.063  41.020  22.793  1.00 61.31  ? 395 ILE B O   1 
ATOM 5748 C CB  . ILE D 4 259 ? -93.309  40.258  23.486  1.00 57.58  ? 395 ILE B CB  1 
ATOM 5749 C CG1 . ILE D 4 259 ? -92.618  40.110  24.844  1.00 60.77  ? 395 ILE B CG1 1 
ATOM 5750 C CG2 . ILE D 4 259 ? -94.410  39.220  23.309  1.00 56.65  ? 395 ILE B CG2 1 
ATOM 5751 C CD1 . ILE D 4 259 ? -93.543  40.298  26.028  1.00 50.31  ? 395 ILE B CD1 1 
ATOM 5752 N N   . MET D 4 260 ? -91.681  42.505  22.305  1.00 49.60  ? 396 MET B N   1 
ATOM 5753 C CA  . MET D 4 260 ? -90.904  43.688  22.637  1.00 52.78  ? 396 MET B CA  1 
ATOM 5754 C C   . MET D 4 260 ? -91.803  44.671  23.374  1.00 61.93  ? 396 MET B C   1 
ATOM 5755 O O   . MET D 4 260 ? -93.024  44.682  23.187  1.00 65.44  ? 396 MET B O   1 
ATOM 5756 C CB  . MET D 4 260 ? -90.290  44.335  21.385  1.00 46.80  ? 396 MET B CB  1 
ATOM 5757 C CG  . MET D 4 260 ? -91.205  45.303  20.655  1.00 62.01  ? 396 MET B CG  1 
ATOM 5758 S SD  . MET D 4 260 ? -90.360  46.260  19.378  1.00 78.38  ? 396 MET B SD  1 
ATOM 5759 C CE  . MET D 4 260 ? -89.716  47.631  20.334  1.00 58.28  ? 396 MET B CE  1 
ATOM 5760 N N   . THR D 4 261 ? -91.194  45.482  24.233  1.00 52.26  ? 397 THR B N   1 
ATOM 5761 C CA  . THR D 4 261 ? -91.928  46.417  25.070  1.00 52.50  ? 397 THR B CA  1 
ATOM 5762 C C   . THR D 4 261 ? -91.520  47.847  24.746  1.00 62.61  ? 397 THR B C   1 
ATOM 5763 O O   . THR D 4 261 ? -90.393  48.109  24.315  1.00 57.04  ? 397 THR B O   1 
ATOM 5764 C CB  . THR D 4 261 ? -91.692  46.145  26.553  1.00 53.99  ? 397 THR B CB  1 
ATOM 5765 O OG1 . THR D 4 261 ? -90.334  46.455  26.882  1.00 61.55  ? 397 THR B OG1 1 
ATOM 5766 C CG2 . THR D 4 261 ? -91.967  44.685  26.872  1.00 58.56  ? 397 THR B CG2 1 
ATOM 5767 N N   . SER D 4 262 ? -92.456  48.769  24.954  1.00 52.46  ? 398 SER B N   1 
ATOM 5768 C CA  . SER D 4 262 ? -92.230  50.172  24.641  1.00 57.61  ? 398 SER B CA  1 
ATOM 5769 C C   . SER D 4 262 ? -93.230  51.017  25.414  1.00 55.09  ? 398 SER B C   1 
ATOM 5770 O O   . SER D 4 262 ? -94.229  50.513  25.934  1.00 46.24  ? 398 SER B O   1 
ATOM 5771 C CB  . SER D 4 262 ? -92.350  50.431  23.135  1.00 70.16  ? 398 SER B CB  1 
ATOM 5772 O OG  . SER D 4 262 ? -92.844  51.733  22.871  1.00 81.27  ? 398 SER B OG  1 
ATOM 5773 N N   . LYS D 4 263 ? -92.938  52.314  25.488  1.00 57.04  ? 399 LYS B N   1 
ATOM 5774 C CA  . LYS D 4 263 ? -93.856  53.295  26.046  1.00 53.61  ? 399 LYS B CA  1 
ATOM 5775 C C   . LYS D 4 263 ? -94.380  54.266  24.999  1.00 61.59  ? 399 LYS B C   1 
ATOM 5776 O O   . LYS D 4 263 ? -95.107  55.202  25.351  1.00 72.74  ? 399 LYS B O   1 
ATOM 5777 C CB  . LYS D 4 263 ? -93.179  54.072  27.182  1.00 76.66  ? 399 LYS B CB  1 
ATOM 5778 C CG  . LYS D 4 263 ? -93.265  53.388  28.537  1.00 80.62  ? 399 LYS B CG  1 
ATOM 5779 C CD  . LYS D 4 263 ? -92.555  54.186  29.623  1.00 88.39  ? 399 LYS B CD  1 
ATOM 5780 C CE  . LYS D 4 263 ? -93.498  55.152  30.323  1.00 102.30 ? 399 LYS B CE  1 
ATOM 5781 N NZ  . LYS D 4 263 ? -93.841  56.318  29.462  1.00 99.12  ? 399 LYS B NZ  1 
ATOM 5782 N N   . THR D 4 264 ? -94.038  54.070  23.728  1.00 59.75  ? 400 THR B N   1 
ATOM 5783 C CA  . THR D 4 264 ? -94.486  54.953  22.656  1.00 74.61  ? 400 THR B CA  1 
ATOM 5784 C C   . THR D 4 264 ? -95.770  54.387  22.062  1.00 64.59  ? 400 THR B C   1 
ATOM 5785 O O   . THR D 4 264 ? -95.760  53.321  21.440  1.00 69.01  ? 400 THR B O   1 
ATOM 5786 C CB  . THR D 4 264 ? -93.409  55.106  21.584  1.00 84.44  ? 400 THR B CB  1 
ATOM 5787 O OG1 . THR D 4 264 ? -93.244  53.868  20.879  1.00 81.21  ? 400 THR B OG1 1 
ATOM 5788 C CG2 . THR D 4 264 ? -92.089  55.503  22.218  1.00 79.38  ? 400 THR B CG2 1 
ATOM 5789 N N   . ASP D 4 265 ? -96.874  55.102  22.256  1.00 71.40  ? 401 ASP B N   1 
ATOM 5790 C CA  . ASP D 4 265 ? -98.177  54.701  21.734  1.00 64.35  ? 401 ASP B CA  1 
ATOM 5791 C C   . ASP D 4 265 ? -98.418  55.485  20.450  1.00 72.28  ? 401 ASP B C   1 
ATOM 5792 O O   . ASP D 4 265 ? -98.762  56.669  20.484  1.00 73.67  ? 401 ASP B O   1 
ATOM 5793 C CB  . ASP D 4 265 ? -99.276  54.942  22.765  1.00 61.22  ? 401 ASP B CB  1 
ATOM 5794 C CG  . ASP D 4 265 ? -99.250  56.349  23.332  1.00 83.18  ? 401 ASP B CG  1 
ATOM 5795 O OD1 . ASP D 4 265 ? -98.143  56.898  23.522  1.00 95.47  ? 401 ASP B OD1 1 
ATOM 5796 O OD2 . ASP D 4 265 ? -100.339 56.909  23.580  1.00 91.86  ? 401 ASP B OD2 1 
ATOM 5797 N N   . VAL D 4 266 ? -98.229  54.821  19.312  1.00 60.49  ? 402 VAL B N   1 
ATOM 5798 C CA  . VAL D 4 266 ? -98.392  55.446  18.006  1.00 66.39  ? 402 VAL B CA  1 
ATOM 5799 C C   . VAL D 4 266 ? -99.358  54.605  17.183  1.00 55.15  ? 402 VAL B C   1 
ATOM 5800 O O   . VAL D 4 266 ? -99.337  53.371  17.247  1.00 60.59  ? 402 VAL B O   1 
ATOM 5801 C CB  . VAL D 4 266 ? -97.037  55.628  17.283  1.00 59.95  ? 402 VAL B CB  1 
ATOM 5802 C CG1 . VAL D 4 266 ? -96.431  54.284  16.877  1.00 62.90  ? 402 VAL B CG1 1 
ATOM 5803 C CG2 . VAL D 4 266 ? -97.191  56.549  16.085  1.00 61.27  ? 402 VAL B CG2 1 
ATOM 5804 N N   . SER D 4 267 ? -100.231 55.276  16.438  1.00 46.50  ? 403 SER B N   1 
ATOM 5805 C CA  . SER D 4 267 ? -101.259 54.599  15.663  1.00 43.72  ? 403 SER B CA  1 
ATOM 5806 C C   . SER D 4 267 ? -100.723 54.154  14.308  1.00 51.71  ? 403 SER B C   1 
ATOM 5807 O O   . SER D 4 267 ? -99.998  54.892  13.634  1.00 44.51  ? 403 SER B O   1 
ATOM 5808 C CB  . SER D 4 267 ? -102.474 55.506  15.464  1.00 42.70  ? 403 SER B CB  1 
ATOM 5809 O OG  . SER D 4 267 ? -103.000 55.939  16.698  1.00 40.49  ? 403 SER B OG  1 
ATOM 5810 N N   . SER D 4 268 ? -101.101 52.943  13.912  1.00 37.02  ? 404 SER B N   1 
ATOM 5811 C CA  . SER D 4 268 ? -100.679 52.376  12.641  1.00 48.57  ? 404 SER B CA  1 
ATOM 5812 C C   . SER D 4 268 ? -101.663 51.282  12.261  1.00 54.88  ? 404 SER B C   1 
ATOM 5813 O O   . SER D 4 268 ? -102.546 50.913  13.039  1.00 46.75  ? 404 SER B O   1 
ATOM 5814 C CB  . SER D 4 268 ? -99.254  51.822  12.718  1.00 59.25  ? 404 SER B CB  1 
ATOM 5815 O OG  . SER D 4 268 ? -99.200  50.699  13.582  1.00 65.59  ? 404 SER B OG  1 
ATOM 5816 N N   . SER D 4 269 ? -101.490 50.757  11.051  1.00 55.10  ? 405 SER B N   1 
ATOM 5817 C CA  . SER D 4 269 ? -102.308 49.656  10.572  1.00 49.25  ? 405 SER B CA  1 
ATOM 5818 C C   . SER D 4 269 ? -101.419 48.624  9.899   1.00 41.88  ? 405 SER B C   1 
ATOM 5819 O O   . SER D 4 269 ? -100.345 48.947  9.386   1.00 45.61  ? 405 SER B O   1 
ATOM 5820 C CB  . SER D 4 269 ? -103.389 50.135  9.598   1.00 49.73  ? 405 SER B CB  1 
ATOM 5821 O OG  . SER D 4 269 ? -104.131 49.042  9.089   1.00 48.60  ? 405 SER B OG  1 
ATOM 5822 N N   . VAL D 4 270 ? -101.868 47.373  9.930   1.00 41.86  ? 406 VAL B N   1 
ATOM 5823 C CA  . VAL D 4 270 ? -101.210 46.272  9.235   1.00 48.11  ? 406 VAL B CA  1 
ATOM 5824 C C   . VAL D 4 270 ? -102.236 45.623  8.319   1.00 50.29  ? 406 VAL B C   1 
ATOM 5825 O O   . VAL D 4 270 ? -103.267 45.126  8.787   1.00 55.59  ? 406 VAL B O   1 
ATOM 5826 C CB  . VAL D 4 270 ? -100.618 45.241  10.208  1.00 43.16  ? 406 VAL B CB  1 
ATOM 5827 C CG1 . VAL D 4 270 ? -100.233 43.974  9.457   1.00 45.28  ? 406 VAL B CG1 1 
ATOM 5828 C CG2 . VAL D 4 270 ? -99.410  45.819  10.920  1.00 45.66  ? 406 VAL B CG2 1 
ATOM 5829 N N   . ILE D 4 271 ? -101.955 45.626  7.020   1.00 50.97  ? 407 ILE B N   1 
ATOM 5830 C CA  . ILE D 4 271 ? -102.839 44.991  6.050   1.00 47.35  ? 407 ILE B CA  1 
ATOM 5831 C C   . ILE D 4 271 ? -102.503 43.507  5.991   1.00 43.05  ? 407 ILE B C   1 
ATOM 5832 O O   . ILE D 4 271 ? -101.377 43.128  5.655   1.00 59.20  ? 407 ILE B O   1 
ATOM 5833 C CB  . ILE D 4 271 ? -102.707 45.647  4.670   1.00 45.34  ? 407 ILE B CB  1 
ATOM 5834 C CG1 . ILE D 4 271 ? -103.013 47.144  4.766   1.00 49.82  ? 407 ILE B CG1 1 
ATOM 5835 C CG2 . ILE D 4 271 ? -103.623 44.961  3.667   1.00 46.45  ? 407 ILE B CG2 1 
ATOM 5836 C CD1 . ILE D 4 271 ? -104.379 47.457  5.333   1.00 39.99  ? 407 ILE B CD1 1 
ATOM 5837 N N   . THR D 4 272 ? -103.473 42.668  6.328   1.00 45.35  ? 408 THR B N   1 
ATOM 5838 C CA  . THR D 4 272 ? -103.287 41.229  6.329   1.00 42.85  ? 408 THR B CA  1 
ATOM 5839 C C   . THR D 4 272 ? -103.830 40.637  5.029   1.00 56.09  ? 408 THR B C   1 
ATOM 5840 O O   . THR D 4 272 ? -104.255 41.356  4.117   1.00 48.64  ? 408 THR B O   1 
ATOM 5841 C CB  . THR D 4 272 ? -103.961 40.610  7.555   1.00 54.62  ? 408 THR B CB  1 
ATOM 5842 O OG1 . THR D 4 272 ? -105.376 40.825  7.486   1.00 46.36  ? 408 THR B OG1 1 
ATOM 5843 C CG2 . THR D 4 272 ? -103.425 41.242  8.832   1.00 55.11  ? 408 THR B CG2 1 
ATOM 5844 N N   . SER D 4 273 ? -103.820 39.305  4.942   1.00 59.02  ? 409 SER B N   1 
ATOM 5845 C CA  . SER D 4 273 ? -104.264 38.633  3.725   1.00 47.46  ? 409 SER B CA  1 
ATOM 5846 C C   . SER D 4 273 ? -105.741 38.886  3.454   1.00 62.46  ? 409 SER B C   1 
ATOM 5847 O O   . SER D 4 273 ? -106.137 39.124  2.306   1.00 78.28  ? 409 SER B O   1 
ATOM 5848 C CB  . SER D 4 273 ? -103.992 37.133  3.827   1.00 49.60  ? 409 SER B CB  1 
ATOM 5849 O OG  . SER D 4 273 ? -102.640 36.878  4.166   1.00 62.01  ? 409 SER B OG  1 
ATOM 5850 N N   . LEU D 4 274 ? -106.573 38.842  4.495   1.00 58.59  ? 410 LEU B N   1 
ATOM 5851 C CA  . LEU D 4 274 ? -108.017 38.947  4.334   1.00 52.88  ? 410 LEU B CA  1 
ATOM 5852 C C   . LEU D 4 274 ? -108.626 40.073  5.158   1.00 55.13  ? 410 LEU B C   1 
ATOM 5853 O O   . LEU D 4 274 ? -109.851 40.111  5.323   1.00 60.52  ? 410 LEU B O   1 
ATOM 5854 C CB  . LEU D 4 274 ? -108.684 37.617  4.697   1.00 59.44  ? 410 LEU B CB  1 
ATOM 5855 C CG  . LEU D 4 274 ? -108.348 36.453  3.761   1.00 53.56  ? 410 LEU B CG  1 
ATOM 5856 C CD1 . LEU D 4 274 ? -108.710 35.114  4.395   1.00 58.31  ? 410 LEU B CD1 1 
ATOM 5857 C CD2 . LEU D 4 274 ? -109.025 36.628  2.413   1.00 70.06  ? 410 LEU B CD2 1 
ATOM 5858 N N   . GLY D 4 275 ? -107.817 40.983  5.678   1.00 68.69  ? 411 GLY B N   1 
ATOM 5859 C CA  . GLY D 4 275 ? -108.345 42.039  6.513   1.00 60.04  ? 411 GLY B CA  1 
ATOM 5860 C C   . GLY D 4 275 ? -107.282 43.049  6.874   1.00 50.94  ? 411 GLY B C   1 
ATOM 5861 O O   . GLY D 4 275 ? -106.229 43.122  6.240   1.00 72.63  ? 411 GLY B O   1 
ATOM 5862 N N   . ALA D 4 276 ? -107.574 43.834  7.906   1.00 48.81  ? 412 ALA B N   1 
ATOM 5863 C CA  . ALA D 4 276 ? -106.652 44.855  8.377   1.00 50.09  ? 412 ALA B CA  1 
ATOM 5864 C C   . ALA D 4 276 ? -106.692 44.920  9.895   1.00 54.43  ? 412 ALA B C   1 
ATOM 5865 O O   . ALA D 4 276 ? -107.767 44.898  10.500  1.00 47.48  ? 412 ALA B O   1 
ATOM 5866 C CB  . ALA D 4 276 ? -106.988 46.231  7.788   1.00 37.05  ? 412 ALA B CB  1 
ATOM 5867 N N   . ILE D 4 277 ? -105.510 44.991  10.502  1.00 53.57  ? 413 ILE B N   1 
ATOM 5868 C CA  . ILE D 4 277 ? -105.362 45.247  11.927  1.00 40.23  ? 413 ILE B CA  1 
ATOM 5869 C C   . ILE D 4 277 ? -105.161 46.743  12.114  1.00 50.94  ? 413 ILE B C   1 
ATOM 5870 O O   . ILE D 4 277 ? -104.318 47.350  11.442  1.00 50.27  ? 413 ILE B O   1 
ATOM 5871 C CB  . ILE D 4 277 ? -104.185 44.458  12.523  1.00 46.14  ? 413 ILE B CB  1 
ATOM 5872 C CG1 . ILE D 4 277 ? -104.348 42.962  12.262  1.00 43.21  ? 413 ILE B CG1 1 
ATOM 5873 C CG2 . ILE D 4 277 ? -104.055 44.740  14.018  1.00 40.72  ? 413 ILE B CG2 1 
ATOM 5874 C CD1 . ILE D 4 277 ? -103.236 42.122  12.857  1.00 34.97  ? 413 ILE B CD1 1 
ATOM 5875 N N   . VAL D 4 278 ? -105.932 47.340  13.017  1.00 56.00  ? 414 VAL B N   1 
ATOM 5876 C CA  . VAL D 4 278 ? -105.848 48.767  13.305  1.00 56.85  ? 414 VAL B CA  1 
ATOM 5877 C C   . VAL D 4 278 ? -105.444 48.940  14.762  1.00 55.59  ? 414 VAL B C   1 
ATOM 5878 O O   . VAL D 4 278 ? -106.135 48.453  15.665  1.00 57.93  ? 414 VAL B O   1 
ATOM 5879 C CB  . VAL D 4 278 ? -107.174 49.485  13.010  1.00 55.99  ? 414 VAL B CB  1 
ATOM 5880 C CG1 . VAL D 4 278 ? -107.143 50.902  13.553  1.00 52.30  ? 414 VAL B CG1 1 
ATOM 5881 C CG2 . VAL D 4 278 ? -107.434 49.502  11.512  1.00 32.81  ? 414 VAL B CG2 1 
ATOM 5882 N N   . SER D 4 279 ? -104.322 49.625  14.987  1.00 52.76  ? 415 SER B N   1 
ATOM 5883 C CA  . SER D 4 279 ? -103.867 50.014  16.321  1.00 44.67  ? 415 SER B CA  1 
ATOM 5884 C C   . SER D 4 279 ? -104.098 51.515  16.465  1.00 54.46  ? 415 SER B C   1 
ATOM 5885 O O   . SER D 4 279 ? -103.335 52.321  15.928  1.00 43.21  ? 415 SER B O   1 
ATOM 5886 C CB  . SER D 4 279 ? -102.397 49.660  16.536  1.00 45.02  ? 415 SER B CB  1 
ATOM 5887 O OG  . SER D 4 279 ? -102.183 48.261  16.506  1.00 62.42  ? 415 SER B OG  1 
ATOM 5888 N N   . CYS D 4 280 ? -105.138 51.888  17.205  1.00 58.29  ? 416 CYS B N   1 
ATOM 5889 C CA  . CYS D 4 280 ? -105.520 53.285  17.377  1.00 62.86  ? 416 CYS B CA  1 
ATOM 5890 C C   . CYS D 4 280 ? -105.201 53.698  18.809  1.00 55.77  ? 416 CYS B C   1 
ATOM 5891 O O   . CYS D 4 280 ? -105.643 53.041  19.758  1.00 50.23  ? 416 CYS B O   1 
ATOM 5892 C CB  . CYS D 4 280 ? -107.005 53.480  17.064  1.00 46.30  ? 416 CYS B CB  1 
ATOM 5893 S SG  . CYS D 4 280 ? -107.458 55.126  16.482  1.00 81.58  ? 416 CYS B SG  1 
ATOM 5894 N N   . TYR D 4 281 ? -104.428 54.773  18.964  1.00 42.94  ? 417 TYR B N   1 
ATOM 5895 C CA  . TYR D 4 281 ? -104.019 55.240  20.282  1.00 49.94  ? 417 TYR B CA  1 
ATOM 5896 C C   . TYR D 4 281 ? -103.982 56.762  20.306  1.00 59.63  ? 417 TYR B C   1 
ATOM 5897 O O   . TYR D 4 281 ? -103.877 57.420  19.268  1.00 62.40  ? 417 TYR B O   1 
ATOM 5898 C CB  . TYR D 4 281 ? -102.651 54.667  20.690  1.00 51.18  ? 417 TYR B CB  1 
ATOM 5899 C CG  . TYR D 4 281 ? -102.602 53.157  20.651  1.00 48.64  ? 417 TYR B CG  1 
ATOM 5900 C CD1 . TYR D 4 281 ? -103.245 52.399  21.621  1.00 49.31  ? 417 TYR B CD1 1 
ATOM 5901 C CD2 . TYR D 4 281 ? -101.895 52.490  19.661  1.00 46.16  ? 417 TYR B CD2 1 
ATOM 5902 C CE1 . TYR D 4 281 ? -103.209 51.019  21.589  1.00 45.35  ? 417 TYR B CE1 1 
ATOM 5903 C CE2 . TYR D 4 281 ? -101.846 51.109  19.626  1.00 43.53  ? 417 TYR B CE2 1 
ATOM 5904 C CZ  . TYR D 4 281 ? -102.505 50.379  20.590  1.00 45.62  ? 417 TYR B CZ  1 
ATOM 5905 O OH  . TYR D 4 281 ? -102.461 49.006  20.556  1.00 50.58  ? 417 TYR B OH  1 
ATOM 5906 N N   . GLY D 4 282 ? -104.069 57.315  21.517  1.00 54.12  ? 418 GLY B N   1 
ATOM 5907 C CA  . GLY D 4 282 ? -104.064 58.762  21.670  1.00 51.50  ? 418 GLY B CA  1 
ATOM 5908 C C   . GLY D 4 282 ? -105.353 59.377  21.160  1.00 58.66  ? 418 GLY B C   1 
ATOM 5909 O O   . GLY D 4 282 ? -106.456 58.899  21.448  1.00 69.46  ? 418 GLY B O   1 
ATOM 5910 N N   . LYS D 4 283 ? -105.218 60.460  20.391  1.00 59.89  ? 419 LYS B N   1 
ATOM 5911 C CA  . LYS D 4 283 ? -106.354 61.129  19.768  1.00 68.03  ? 419 LYS B CA  1 
ATOM 5912 C C   . LYS D 4 283 ? -106.372 60.958  18.251  1.00 63.99  ? 419 LYS B C   1 
ATOM 5913 O O   . LYS D 4 283 ? -106.951 61.789  17.543  1.00 56.88  ? 419 LYS B O   1 
ATOM 5914 C CB  . LYS D 4 283 ? -106.367 62.611  20.141  1.00 63.36  ? 419 LYS B CB  1 
ATOM 5915 C CG  . LYS D 4 283 ? -106.288 62.854  21.635  1.00 75.64  ? 419 LYS B CG  1 
ATOM 5916 C CD  . LYS D 4 283 ? -106.316 64.329  21.983  1.00 97.31  ? 419 LYS B CD  1 
ATOM 5917 C CE  . LYS D 4 283 ? -105.078 64.713  22.767  1.00 96.49  ? 419 LYS B CE  1 
ATOM 5918 N NZ  . LYS D 4 283 ? -105.226 66.036  23.427  1.00 108.60 ? 419 LYS B NZ  1 
ATOM 5919 N N   . THR D 4 284 ? -105.753 59.896  17.739  1.00 63.14  ? 420 THR B N   1 
ATOM 5920 C CA  . THR D 4 284 ? -105.759 59.639  16.304  1.00 62.55  ? 420 THR B CA  1 
ATOM 5921 C C   . THR D 4 284 ? -107.148 59.210  15.846  1.00 60.37  ? 420 THR B C   1 
ATOM 5922 O O   . THR D 4 284 ? -107.853 58.478  16.546  1.00 65.53  ? 420 THR B O   1 
ATOM 5923 C CB  . THR D 4 284 ? -104.736 58.558  15.951  1.00 51.60  ? 420 THR B CB  1 
ATOM 5924 O OG1 . THR D 4 284 ? -103.464 58.888  16.524  1.00 68.34  ? 420 THR B OG1 1 
ATOM 5925 C CG2 . THR D 4 284 ? -104.579 58.434  14.438  1.00 63.47  ? 420 THR B CG2 1 
ATOM 5926 N N   . LYS D 4 285 ? -107.542 59.667  14.657  1.00 54.36  ? 421 LYS B N   1 
ATOM 5927 C CA  . LYS D 4 285 ? -108.834 59.324  14.075  1.00 55.10  ? 421 LYS B CA  1 
ATOM 5928 C C   . LYS D 4 285 ? -108.635 58.158  13.111  1.00 48.24  ? 421 LYS B C   1 
ATOM 5929 O O   . LYS D 4 285 ? -108.078 58.331  12.022  1.00 63.70  ? 421 LYS B O   1 
ATOM 5930 C CB  . LYS D 4 285 ? -109.453 60.532  13.376  1.00 45.49  ? 421 LYS B CB  1 
ATOM 5931 C CG  . LYS D 4 285 ? -110.862 60.298  12.855  1.00 46.88  ? 421 LYS B CG  1 
ATOM 5932 C CD  . LYS D 4 285 ? -111.477 61.595  12.354  1.00 80.93  ? 421 LYS B CD  1 
ATOM 5933 C CE  . LYS D 4 285 ? -112.904 61.384  11.875  1.00 105.42 ? 421 LYS B CE  1 
ATOM 5934 N NZ  . LYS D 4 285 ? -112.972 61.196  10.397  1.00 81.77  ? 421 LYS B NZ  1 
ATOM 5935 N N   . CYS D 4 286 ? -109.091 56.975  13.514  1.00 54.14  ? 422 CYS B N   1 
ATOM 5936 C CA  . CYS D 4 286 ? -108.959 55.753  12.731  1.00 48.01  ? 422 CYS B CA  1 
ATOM 5937 C C   . CYS D 4 286 ? -110.338 55.315  12.253  1.00 53.95  ? 422 CYS B C   1 
ATOM 5938 O O   . CYS D 4 286 ? -111.254 55.146  13.065  1.00 65.66  ? 422 CYS B O   1 
ATOM 5939 C CB  . CYS D 4 286 ? -108.305 54.642  13.562  1.00 42.24  ? 422 CYS B CB  1 
ATOM 5940 S SG  . CYS D 4 286 ? -106.849 55.151  14.529  1.00 92.61  ? 422 CYS B SG  1 
ATOM 5941 N N   . THR D 4 287 ? -110.487 55.135  10.940  1.00 46.12  ? 423 THR B N   1 
ATOM 5942 C CA  . THR D 4 287 ? -111.779 54.799  10.357  1.00 51.25  ? 423 THR B CA  1 
ATOM 5943 C C   . THR D 4 287 ? -111.618 53.713  9.302   1.00 54.03  ? 423 THR B C   1 
ATOM 5944 O O   . THR D 4 287 ? -110.553 53.562  8.698   1.00 61.13  ? 423 THR B O   1 
ATOM 5945 C CB  . THR D 4 287 ? -112.456 56.022  9.715   1.00 56.83  ? 423 THR B CB  1 
ATOM 5946 O OG1 . THR D 4 287 ? -111.564 56.624  8.767   1.00 56.84  ? 423 THR B OG1 1 
ATOM 5947 C CG2 . THR D 4 287 ? -112.834 57.047  10.775  1.00 52.20  ? 423 THR B CG2 1 
ATOM 5948 N N   . ALA D 4 288 ? -112.692 52.958  9.089   1.00 50.56  ? 424 ALA B N   1 
ATOM 5949 C CA  . ALA D 4 288 ? -112.783 51.991  8.004   1.00 47.31  ? 424 ALA B CA  1 
ATOM 5950 C C   . ALA D 4 288 ? -113.834 52.474  7.018   1.00 59.62  ? 424 ALA B C   1 
ATOM 5951 O O   . ALA D 4 288 ? -114.959 52.800  7.413   1.00 52.00  ? 424 ALA B O   1 
ATOM 5952 C CB  . ALA D 4 288 ? -113.136 50.596  8.522   1.00 48.27  ? 424 ALA B CB  1 
ATOM 5953 N N   . SER D 4 289 ? -113.469 52.523  5.744   1.00 59.28  ? 425 SER B N   1 
ATOM 5954 C CA  . SER D 4 289 ? -114.281 53.186  4.741   1.00 52.20  ? 425 SER B CA  1 
ATOM 5955 C C   . SER D 4 289 ? -114.613 52.219  3.614   1.00 63.29  ? 425 SER B C   1 
ATOM 5956 O O   . SER D 4 289 ? -113.893 51.246  3.372   1.00 70.02  ? 425 SER B O   1 
ATOM 5957 C CB  . SER D 4 289 ? -113.558 54.426  4.196   1.00 70.39  ? 425 SER B CB  1 
ATOM 5958 O OG  . SER D 4 289 ? -114.468 55.345  3.620   1.00 78.93  ? 425 SER B OG  1 
ATOM 5959 N N   . ASN D 4 290 ? -115.730 52.486  2.946   1.00 75.40  ? 426 ASN B N   1 
ATOM 5960 C CA  . ASN D 4 290 ? -116.189 51.711  1.805   1.00 78.34  ? 426 ASN B CA  1 
ATOM 5961 C C   . ASN D 4 290 ? -116.257 52.623  0.587   1.00 77.18  ? 426 ASN B C   1 
ATOM 5962 O O   . ASN D 4 290 ? -116.528 53.822  0.708   1.00 75.02  ? 426 ASN B O   1 
ATOM 5963 C CB  . ASN D 4 290 ? -117.562 51.078  2.093   1.00 71.02  ? 426 ASN B CB  1 
ATOM 5964 C CG  . ASN D 4 290 ? -118.035 50.164  0.983   1.00 77.59  ? 426 ASN B CG  1 
ATOM 5965 O OD1 . ASN D 4 290 ? -118.210 50.588  -0.160  1.00 92.23  ? 426 ASN B OD1 1 
ATOM 5966 N ND2 . ASN D 4 290 ? -118.238 48.893  1.314   1.00 81.70  ? 426 ASN B ND2 1 
ATOM 5967 N N   . LYS D 4 291 ? -115.999 52.052  -0.593  1.00 83.72  ? 427 LYS B N   1 
ATOM 5968 C CA  . LYS D 4 291 ? -115.966 52.868  -1.803  1.00 81.45  ? 427 LYS B CA  1 
ATOM 5969 C C   . LYS D 4 291 ? -117.351 53.331  -2.236  1.00 76.60  ? 427 LYS B C   1 
ATOM 5970 O O   . LYS D 4 291 ? -117.457 54.337  -2.946  1.00 85.17  ? 427 LYS B O   1 
ATOM 5971 C CB  . LYS D 4 291 ? -115.286 52.110  -2.947  1.00 80.57  ? 427 LYS B CB  1 
ATOM 5972 C CG  . LYS D 4 291 ? -116.125 51.016  -3.591  1.00 87.16  ? 427 LYS B CG  1 
ATOM 5973 C CD  . LYS D 4 291 ? -115.254 50.073  -4.417  1.00 83.66  ? 427 LYS B CD  1 
ATOM 5974 C CE  . LYS D 4 291 ? -116.009 48.817  -4.824  1.00 80.98  ? 427 LYS B CE  1 
ATOM 5975 N NZ  . LYS D 4 291 ? -117.383 49.113  -5.312  1.00 96.66  ? 427 LYS B NZ  1 
ATOM 5976 N N   . ASN D 4 292 ? -118.412 52.635  -1.825  1.00 82.77  ? 428 ASN B N   1 
ATOM 5977 C CA  . ASN D 4 292 ? -119.771 53.021  -2.174  1.00 80.03  ? 428 ASN B CA  1 
ATOM 5978 C C   . ASN D 4 292 ? -120.550 53.618  -1.011  1.00 83.48  ? 428 ASN B C   1 
ATOM 5979 O O   . ASN D 4 292 ? -121.620 54.194  -1.238  1.00 84.28  ? 428 ASN B O   1 
ATOM 5980 C CB  . ASN D 4 292 ? -120.545 51.813  -2.728  1.00 75.49  ? 428 ASN B CB  1 
ATOM 5981 C CG  . ASN D 4 292 ? -120.127 51.448  -4.140  1.00 86.97  ? 428 ASN B CG  1 
ATOM 5982 O OD1 . ASN D 4 292 ? -119.719 50.317  -4.406  1.00 96.91  ? 428 ASN B OD1 1 
ATOM 5983 N ND2 . ASN D 4 292 ? -120.229 52.407  -5.054  1.00 85.74  ? 428 ASN B ND2 1 
ATOM 5984 N N   . ARG D 4 293 ? -120.048 53.505  0.221   1.00 90.78  ? 429 ARG B N   1 
ATOM 5985 C CA  . ARG D 4 293 ? -120.758 53.990  1.395   1.00 68.82  ? 429 ARG B CA  1 
ATOM 5986 C C   . ARG D 4 293 ? -120.003 55.037  2.199   1.00 73.47  ? 429 ARG B C   1 
ATOM 5987 O O   . ARG D 4 293 ? -120.623 55.701  3.038   1.00 81.67  ? 429 ARG B O   1 
ATOM 5988 C CB  . ARG D 4 293 ? -121.105 52.823  2.331   1.00 56.85  ? 429 ARG B CB  1 
ATOM 5989 C CG  . ARG D 4 293 ? -122.359 52.067  1.945   1.00 80.46  ? 429 ARG B CG  1 
ATOM 5990 C CD  . ARG D 4 293 ? -122.422 50.729  2.659   1.00 91.42  ? 429 ARG B CD  1 
ATOM 5991 N NE  . ARG D 4 293 ? -122.806 50.879  4.057   1.00 99.57  ? 429 ARG B NE  1 
ATOM 5992 C CZ  . ARG D 4 293 ? -122.566 49.978  4.998   1.00 100.69 ? 429 ARG B CZ  1 
ATOM 5993 N NH1 . ARG D 4 293 ? -121.946 48.842  4.724   1.00 105.24 ? 429 ARG B NH1 1 
ATOM 5994 N NH2 . ARG D 4 293 ? -122.960 50.221  6.245   1.00 95.63  ? 429 ARG B NH2 1 
ATOM 5995 N N   . GLY D 4 294 ? -118.702 55.208  1.977   1.00 69.16  ? 430 GLY B N   1 
ATOM 5996 C CA  . GLY D 4 294 ? -117.931 56.123  2.798   1.00 54.63  ? 430 GLY B CA  1 
ATOM 5997 C C   . GLY D 4 294 ? -117.483 55.474  4.099   1.00 69.50  ? 430 GLY B C   1 
ATOM 5998 O O   . GLY D 4 294 ? -117.304 54.258  4.187   1.00 65.99  ? 430 GLY B O   1 
ATOM 5999 N N   . ILE D 4 295 ? -117.297 56.308  5.121   1.00 67.82  ? 431 ILE B N   1 
ATOM 6000 C CA  . ILE D 4 295 ? -116.874 55.820  6.431   1.00 58.50  ? 431 ILE B CA  1 
ATOM 6001 C C   . ILE D 4 295 ? -117.996 54.993  7.043   1.00 54.86  ? 431 ILE B C   1 
ATOM 6002 O O   . ILE D 4 295 ? -119.106 55.492  7.261   1.00 67.36  ? 431 ILE B O   1 
ATOM 6003 C CB  . ILE D 4 295 ? -116.481 56.984  7.350   1.00 53.55  ? 431 ILE B CB  1 
ATOM 6004 C CG1 . ILE D 4 295 ? -115.345 57.797  6.725   1.00 59.46  ? 431 ILE B CG1 1 
ATOM 6005 C CG2 . ILE D 4 295 ? -116.099 56.471  8.731   1.00 52.53  ? 431 ILE B CG2 1 
ATOM 6006 C CD1 . ILE D 4 295 ? -114.980 59.031  7.513   1.00 48.22  ? 431 ILE B CD1 1 
ATOM 6007 N N   . ILE D 4 296 ? -117.708 53.727  7.334   1.00 59.41  ? 432 ILE B N   1 
ATOM 6008 C CA  . ILE D 4 296 ? -118.699 52.810  7.887   1.00 63.55  ? 432 ILE B CA  1 
ATOM 6009 C C   . ILE D 4 296 ? -118.335 52.310  9.275   1.00 50.93  ? 432 ILE B C   1 
ATOM 6010 O O   . ILE D 4 296 ? -119.155 51.621  9.900   1.00 60.34  ? 432 ILE B O   1 
ATOM 6011 C CB  . ILE D 4 296 ? -118.947 51.610  6.949   1.00 66.64  ? 432 ILE B CB  1 
ATOM 6012 C CG1 . ILE D 4 296 ? -117.665 50.792  6.783   1.00 55.97  ? 432 ILE B CG1 1 
ATOM 6013 C CG2 . ILE D 4 296 ? -119.478 52.084  5.607   1.00 58.27  ? 432 ILE B CG2 1 
ATOM 6014 C CD1 . ILE D 4 296 ? -117.794 49.655  5.801   1.00 65.67  ? 432 ILE B CD1 1 
ATOM 6015 N N   . LYS D 4 297 ? -117.134 52.604  9.768   1.00 61.28  ? 433 LYS B N   1 
ATOM 6016 C CA  . LYS D 4 297 ? -116.755 52.280  11.134  1.00 52.94  ? 433 LYS B CA  1 
ATOM 6017 C C   . LYS D 4 297 ? -115.721 53.289  11.605  1.00 54.24  ? 433 LYS B C   1 
ATOM 6018 O O   . LYS D 4 297 ? -114.840 53.685  10.838  1.00 53.78  ? 433 LYS B O   1 
ATOM 6019 C CB  . LYS D 4 297 ? -116.190 50.857  11.255  1.00 47.44  ? 433 LYS B CB  1 
ATOM 6020 C CG  . LYS D 4 297 ? -115.950 50.429  12.697  1.00 61.73  ? 433 LYS B CG  1 
ATOM 6021 C CD  . LYS D 4 297 ? -115.545 48.969  12.824  1.00 61.06  ? 433 LYS B CD  1 
ATOM 6022 C CE  . LYS D 4 297 ? -115.446 48.577  14.297  1.00 61.97  ? 433 LYS B CE  1 
ATOM 6023 N NZ  . LYS D 4 297 ? -115.186 47.126  14.506  1.00 68.20  ? 433 LYS B NZ  1 
ATOM 6024 N N   . THR D 4 298 ? -115.843 53.710  12.864  1.00 61.40  ? 434 THR B N   1 
ATOM 6025 C CA  . THR D 4 298 ? -114.844 54.548  13.519  1.00 43.34  ? 434 THR B CA  1 
ATOM 6026 C C   . THR D 4 298 ? -114.244 53.734  14.656  1.00 46.47  ? 434 THR B C   1 
ATOM 6027 O O   . THR D 4 298 ? -114.941 53.409  15.623  1.00 62.60  ? 434 THR B O   1 
ATOM 6028 C CB  . THR D 4 298 ? -115.448 55.850  14.043  1.00 40.21  ? 434 THR B CB  1 
ATOM 6029 O OG1 . THR D 4 298 ? -116.007 56.598  12.956  1.00 49.68  ? 434 THR B OG1 1 
ATOM 6030 C CG2 . THR D 4 298 ? -114.368 56.691  14.701  1.00 46.63  ? 434 THR B CG2 1 
ATOM 6031 N N   . PHE D 4 299 ? -112.963 53.398  14.537  1.00 56.03  ? 435 PHE B N   1 
ATOM 6032 C CA  . PHE D 4 299 ? -112.308 52.576  15.546  1.00 61.02  ? 435 PHE B CA  1 
ATOM 6033 C C   . PHE D 4 299 ? -112.115 53.352  16.843  1.00 49.59  ? 435 PHE B C   1 
ATOM 6034 O O   . PHE D 4 299 ? -111.825 54.551  16.833  1.00 63.30  ? 435 PHE B O   1 
ATOM 6035 C CB  . PHE D 4 299 ? -110.955 52.082  15.037  1.00 43.30  ? 435 PHE B CB  1 
ATOM 6036 C CG  . PHE D 4 299 ? -111.045 51.210  13.818  1.00 50.72  ? 435 PHE B CG  1 
ATOM 6037 C CD1 . PHE D 4 299 ? -111.324 49.859  13.938  1.00 40.58  ? 435 PHE B CD1 1 
ATOM 6038 C CD2 . PHE D 4 299 ? -110.842 51.740  12.553  1.00 58.65  ? 435 PHE B CD2 1 
ATOM 6039 C CE1 . PHE D 4 299 ? -111.404 49.053  12.819  1.00 51.63  ? 435 PHE B CE1 1 
ATOM 6040 C CE2 . PHE D 4 299 ? -110.919 50.937  11.430  1.00 41.50  ? 435 PHE B CE2 1 
ATOM 6041 C CZ  . PHE D 4 299 ? -111.201 49.593  11.563  1.00 43.95  ? 435 PHE B CZ  1 
ATOM 6042 N N   . SER D 4 300 ? -112.285 52.658  17.964  1.00 49.29  ? 436 SER B N   1 
ATOM 6043 C CA  . SER D 4 300 ? -111.935 53.202  19.267  1.00 59.47  ? 436 SER B CA  1 
ATOM 6044 C C   . SER D 4 300 ? -110.469 52.899  19.578  1.00 56.17  ? 436 SER B C   1 
ATOM 6045 O O   . SER D 4 300 ? -109.789 52.175  18.847  1.00 66.86  ? 436 SER B O   1 
ATOM 6046 C CB  . SER D 4 300 ? -112.853 52.639  20.354  1.00 54.99  ? 436 SER B CB  1 
ATOM 6047 O OG  . SER D 4 300 ? -112.998 51.235  20.232  1.00 61.29  ? 436 SER B OG  1 
ATOM 6048 N N   . ASN D 4 301 ? -109.979 53.474  20.673  1.00 55.47  ? 437 ASN B N   1 
ATOM 6049 C CA  . ASN D 4 301 ? -108.588 53.265  21.053  1.00 48.72  ? 437 ASN B CA  1 
ATOM 6050 C C   . ASN D 4 301 ? -108.343 51.802  21.401  1.00 48.01  ? 437 ASN B C   1 
ATOM 6051 O O   . ASN D 4 301 ? -109.201 51.129  21.979  1.00 54.30  ? 437 ASN B O   1 
ATOM 6052 C CB  . ASN D 4 301 ? -108.205 54.164  22.228  1.00 50.26  ? 437 ASN B CB  1 
ATOM 6053 C CG  . ASN D 4 301 ? -107.886 55.582  21.794  1.00 57.56  ? 437 ASN B CG  1 
ATOM 6054 O OD1 . ASN D 4 301 ? -108.202 55.985  20.675  1.00 71.52  ? 437 ASN B OD1 1 
ATOM 6055 N ND2 . ASN D 4 301 ? -107.242 56.341  22.671  1.00 62.35  ? 437 ASN B ND2 1 
ATOM 6056 N N   . GLY D 4 302 ? -107.168 51.307  21.026  1.00 51.90  ? 438 GLY B N   1 
ATOM 6057 C CA  . GLY D 4 302 ? -106.836 49.911  21.217  1.00 52.43  ? 438 GLY B CA  1 
ATOM 6058 C C   . GLY D 4 302 ? -106.498 49.221  19.912  1.00 56.88  ? 438 GLY B C   1 
ATOM 6059 O O   . GLY D 4 302 ? -106.217 49.882  18.906  1.00 60.22  ? 438 GLY B O   1 
ATOM 6060 N N   . CYS D 4 303 ? -106.528 47.892  19.911  1.00 52.70  ? 439 CYS B N   1 
ATOM 6061 C CA  . CYS D 4 303 ? -106.223 47.095  18.730  1.00 57.41  ? 439 CYS B CA  1 
ATOM 6062 C C   . CYS D 4 303 ? -107.498 46.410  18.256  1.00 57.23  ? 439 CYS B C   1 
ATOM 6063 O O   . CYS D 4 303 ? -108.149 45.700  19.030  1.00 85.11  ? 439 CYS B O   1 
ATOM 6064 C CB  . CYS D 4 303 ? -105.130 46.070  19.032  1.00 55.10  ? 439 CYS B CB  1 
ATOM 6065 S SG  . CYS D 4 303 ? -104.646 45.070  17.613  1.00 90.60  ? 439 CYS B SG  1 
ATOM 6066 N N   . ASP D 4 304 ? -107.850 46.626  16.990  1.00 52.97  ? 440 ASP B N   1 
ATOM 6067 C CA  . ASP D 4 304 ? -109.059 46.079  16.392  1.00 51.83  ? 440 ASP B CA  1 
ATOM 6068 C C   . ASP D 4 304 ? -108.738 45.497  15.021  1.00 52.89  ? 440 ASP B C   1 
ATOM 6069 O O   . ASP D 4 304 ? -107.677 45.746  14.440  1.00 39.97  ? 440 ASP B O   1 
ATOM 6070 C CB  . ASP D 4 304 ? -110.158 47.144  16.256  1.00 53.95  ? 440 ASP B CB  1 
ATOM 6071 C CG  . ASP D 4 304 ? -111.558 46.559  16.337  1.00 54.66  ? 440 ASP B CG  1 
ATOM 6072 O OD1 . ASP D 4 304 ? -111.700 45.318  16.285  1.00 52.85  ? 440 ASP B OD1 1 
ATOM 6073 O OD2 . ASP D 4 304 ? -112.524 47.346  16.422  1.00 55.47  ? 440 ASP B OD2 1 
ATOM 6074 N N   . TYR D 4 305 ? -109.684 44.723  14.498  1.00 50.89  ? 441 TYR B N   1 
ATOM 6075 C CA  . TYR D 4 305 ? -109.543 44.090  13.198  1.00 49.97  ? 441 TYR B CA  1 
ATOM 6076 C C   . TYR D 4 305 ? -110.849 44.225  12.430  1.00 48.78  ? 441 TYR B C   1 
ATOM 6077 O O   . TYR D 4 305 ? -111.934 44.230  13.016  1.00 56.47  ? 441 TYR B O   1 
ATOM 6078 C CB  . TYR D 4 305 ? -109.157 42.613  13.349  1.00 55.33  ? 441 TYR B CB  1 
ATOM 6079 C CG  . TYR D 4 305 ? -109.167 41.813  12.066  1.00 56.79  ? 441 TYR B CG  1 
ATOM 6080 C CD1 . TYR D 4 305 ? -108.034 41.733  11.266  1.00 53.96  ? 441 TYR B CD1 1 
ATOM 6081 C CD2 . TYR D 4 305 ? -110.304 41.122  11.663  1.00 56.61  ? 441 TYR B CD2 1 
ATOM 6082 C CE1 . TYR D 4 305 ? -108.038 40.998  10.096  1.00 62.96  ? 441 TYR B CE1 1 
ATOM 6083 C CE2 . TYR D 4 305 ? -110.316 40.386  10.497  1.00 55.94  ? 441 TYR B CE2 1 
ATOM 6084 C CZ  . TYR D 4 305 ? -109.181 40.326  9.718   1.00 57.86  ? 441 TYR B CZ  1 
ATOM 6085 O OH  . TYR D 4 305 ? -109.194 39.595  8.554   1.00 60.65  ? 441 TYR B OH  1 
ATOM 6086 N N   . VAL D 4 306 ? -110.735 44.339  11.109  1.00 54.72  ? 442 VAL B N   1 
ATOM 6087 C CA  . VAL D 4 306 ? -111.893 44.350  10.223  1.00 53.48  ? 442 VAL B CA  1 
ATOM 6088 C C   . VAL D 4 306 ? -111.563 43.512  8.995   1.00 49.65  ? 442 VAL B C   1 
ATOM 6089 O O   . VAL D 4 306 ? -110.438 43.552  8.487   1.00 63.30  ? 442 VAL B O   1 
ATOM 6090 C CB  . VAL D 4 306 ? -112.312 45.789  9.842   1.00 40.42  ? 442 VAL B CB  1 
ATOM 6091 C CG1 . VAL D 4 306 ? -111.303 46.434  8.898   1.00 44.38  ? 442 VAL B CG1 1 
ATOM 6092 C CG2 . VAL D 4 306 ? -113.704 45.793  9.240   1.00 70.23  ? 442 VAL B CG2 1 
ATOM 6093 N N   . SER D 4 307 ? -112.533 42.721  8.542   1.00 61.86  ? 443 SER B N   1 
ATOM 6094 C CA  . SER D 4 307 ? -112.313 41.883  7.372   1.00 64.13  ? 443 SER B CA  1 
ATOM 6095 C C   . SER D 4 307 ? -112.472 42.701  6.095   1.00 56.87  ? 443 SER B C   1 
ATOM 6096 O O   . SER D 4 307 ? -113.003 43.816  6.099   1.00 57.29  ? 443 SER B O   1 
ATOM 6097 C CB  . SER D 4 307 ? -113.280 40.701  7.348   1.00 58.38  ? 443 SER B CB  1 
ATOM 6098 O OG  . SER D 4 307 ? -114.496 41.059  6.716   1.00 67.51  ? 443 SER B OG  1 
ATOM 6099 N N   . ASN D 4 308 ? -112.007 42.123  4.986   1.00 65.37  ? 444 ASN B N   1 
ATOM 6100 C CA  . ASN D 4 308 ? -112.051 42.813  3.703   1.00 63.67  ? 444 ASN B CA  1 
ATOM 6101 C C   . ASN D 4 308 ? -113.427 42.777  3.048   1.00 57.26  ? 444 ASN B C   1 
ATOM 6102 O O   . ASN D 4 308 ? -113.653 43.521  2.089   1.00 67.12  ? 444 ASN B O   1 
ATOM 6103 C CB  . ASN D 4 308 ? -110.995 42.231  2.754   1.00 55.99  ? 444 ASN B CB  1 
ATOM 6104 C CG  . ASN D 4 308 ? -111.180 40.744  2.493   1.00 54.42  ? 444 ASN B CG  1 
ATOM 6105 O OD1 . ASN D 4 308 ? -112.132 40.123  2.968   1.00 59.17  ? 444 ASN B OD1 1 
ATOM 6106 N ND2 . ASN D 4 308 ? -110.251 40.164  1.740   1.00 53.96  ? 444 ASN B ND2 1 
ATOM 6107 N N   . LYS D 4 309 ? -114.350 41.953  3.541   1.00 54.40  ? 445 LYS B N   1 
ATOM 6108 C CA  . LYS D 4 309 ? -115.713 41.940  3.020   1.00 57.75  ? 445 LYS B CA  1 
ATOM 6109 C C   . LYS D 4 309 ? -116.455 43.179  3.504   1.00 62.78  ? 445 LYS B C   1 
ATOM 6110 O O   . LYS D 4 309 ? -116.646 43.365  4.711   1.00 70.73  ? 445 LYS B O   1 
ATOM 6111 C CB  . LYS D 4 309 ? -116.454 40.677  3.455   1.00 61.73  ? 445 LYS B CB  1 
ATOM 6112 C CG  . LYS D 4 309 ? -115.657 39.396  3.322   1.00 78.50  ? 445 LYS B CG  1 
ATOM 6113 C CD  . LYS D 4 309 ? -116.309 38.267  4.103   1.00 76.97  ? 445 LYS B CD  1 
ATOM 6114 C CE  . LYS D 4 309 ? -115.580 36.957  3.878   1.00 92.64  ? 445 LYS B CE  1 
ATOM 6115 N NZ  . LYS D 4 309 ? -115.477 36.621  2.428   1.00 90.88  ? 445 LYS B NZ  1 
ATOM 6116 N N   . GLY D 4 310 ? -116.879 44.021  2.564   1.00 59.81  ? 446 GLY B N   1 
ATOM 6117 C CA  . GLY D 4 310 ? -117.569 45.250  2.887   1.00 60.37  ? 446 GLY B CA  1 
ATOM 6118 C C   . GLY D 4 310 ? -116.674 46.430  3.195   1.00 67.56  ? 446 GLY B C   1 
ATOM 6119 O O   . GLY D 4 310 ? -117.187 47.544  3.365   1.00 84.33  ? 446 GLY B O   1 
ATOM 6120 N N   . VAL D 4 311 ? -115.359 46.231  3.263   1.00 65.67  ? 447 VAL B N   1 
ATOM 6121 C CA  . VAL D 4 311 ? -114.406 47.292  3.567   1.00 65.18  ? 447 VAL B CA  1 
ATOM 6122 C C   . VAL D 4 311 ? -113.369 47.339  2.454   1.00 56.72  ? 447 VAL B C   1 
ATOM 6123 O O   . VAL D 4 311 ? -112.774 46.310  2.114   1.00 64.79  ? 447 VAL B O   1 
ATOM 6124 C CB  . VAL D 4 311 ? -113.724 47.072  4.933   1.00 61.49  ? 447 VAL B CB  1 
ATOM 6125 C CG1 . VAL D 4 311 ? -112.566 48.042  5.115   1.00 61.93  ? 447 VAL B CG1 1 
ATOM 6126 C CG2 . VAL D 4 311 ? -114.730 47.222  6.060   1.00 46.79  ? 447 VAL B CG2 1 
ATOM 6127 N N   . ASP D 4 312 ? -113.151 48.528  1.888   1.00 56.72  ? 448 ASP B N   1 
ATOM 6128 C CA  . ASP D 4 312 ? -112.157 48.713  0.840   1.00 55.62  ? 448 ASP B CA  1 
ATOM 6129 C C   . ASP D 4 312 ? -111.023 49.648  1.229   1.00 56.19  ? 448 ASP B C   1 
ATOM 6130 O O   . ASP D 4 312 ? -110.040 49.742  0.486   1.00 65.29  ? 448 ASP B O   1 
ATOM 6131 C CB  . ASP D 4 312 ? -112.811 49.248  -0.445  1.00 69.48  ? 448 ASP B CB  1 
ATOM 6132 C CG  . ASP D 4 312 ? -113.904 48.338  -0.970  1.00 80.25  ? 448 ASP B CG  1 
ATOM 6133 O OD1 . ASP D 4 312 ? -113.721 47.102  -0.925  1.00 76.93  ? 448 ASP B OD1 1 
ATOM 6134 O OD2 . ASP D 4 312 ? -114.937 48.859  -1.444  1.00 66.65  ? 448 ASP B OD2 1 
ATOM 6135 N N   . THR D 4 313 ? -111.122 50.333  2.362   1.00 64.75  ? 449 THR B N   1 
ATOM 6136 C CA  . THR D 4 313 ? -110.148 51.348  2.727   1.00 49.83  ? 449 THR B CA  1 
ATOM 6137 C C   . THR D 4 313 ? -110.140 51.504  4.240   1.00 54.67  ? 449 THR B C   1 
ATOM 6138 O O   . THR D 4 313 ? -111.199 51.546  4.870   1.00 56.28  ? 449 THR B O   1 
ATOM 6139 C CB  . THR D 4 313 ? -110.467 52.683  2.038   1.00 43.56  ? 449 THR B CB  1 
ATOM 6140 O OG1 . THR D 4 313 ? -110.091 52.607  0.658   1.00 73.80  ? 449 THR B OG1 1 
ATOM 6141 C CG2 . THR D 4 313 ? -109.743 53.840  2.703   1.00 56.14  ? 449 THR B CG2 1 
ATOM 6142 N N   . VAL D 4 314 ? -108.940 51.559  4.811   1.00 46.76  ? 450 VAL B N   1 
ATOM 6143 C CA  . VAL D 4 314 ? -108.736 51.866  6.220   1.00 51.74  ? 450 VAL B CA  1 
ATOM 6144 C C   . VAL D 4 314 ? -107.828 53.083  6.300   1.00 46.28  ? 450 VAL B C   1 
ATOM 6145 O O   . VAL D 4 314 ? -106.763 53.110  5.674   1.00 48.36  ? 450 VAL B O   1 
ATOM 6146 C CB  . VAL D 4 314 ? -108.135 50.672  6.985   1.00 43.91  ? 450 VAL B CB  1 
ATOM 6147 C CG1 . VAL D 4 314 ? -107.538 51.134  8.292   1.00 52.25  ? 450 VAL B CG1 1 
ATOM 6148 C CG2 . VAL D 4 314 ? -109.205 49.623  7.245   1.00 35.31  ? 450 VAL B CG2 1 
ATOM 6149 N N   . SER D 4 315 ? -108.258 54.093  7.050   1.00 53.15  ? 451 SER B N   1 
ATOM 6150 C CA  . SER D 4 315 ? -107.490 55.316  7.244   1.00 45.34  ? 451 SER B CA  1 
ATOM 6151 C C   . SER D 4 315 ? -107.091 55.424  8.710   1.00 52.33  ? 451 SER B C   1 
ATOM 6152 O O   . SER D 4 315 ? -107.948 55.353  9.598   1.00 38.01  ? 451 SER B O   1 
ATOM 6153 C CB  . SER D 4 315 ? -108.291 56.543  6.809   1.00 46.47  ? 451 SER B CB  1 
ATOM 6154 O OG  . SER D 4 315 ? -108.991 56.292  5.602   1.00 77.15  ? 451 SER B OG  1 
ATOM 6155 N N   . VAL D 4 316 ? -105.793 55.589  8.955   1.00 51.53  ? 452 VAL B N   1 
ATOM 6156 C CA  . VAL D 4 316 ? -105.239 55.756  10.293  1.00 33.38  ? 452 VAL B CA  1 
ATOM 6157 C C   . VAL D 4 316 ? -104.488 57.079  10.310  1.00 39.29  ? 452 VAL B C   1 
ATOM 6158 O O   . VAL D 4 316 ? -103.369 57.172  9.789   1.00 44.40  ? 452 VAL B O   1 
ATOM 6159 C CB  . VAL D 4 316 ? -104.311 54.598  10.682  1.00 41.92  ? 452 VAL B CB  1 
ATOM 6160 C CG1 . VAL D 4 316 ? -103.663 54.866  12.035  1.00 36.16  ? 452 VAL B CG1 1 
ATOM 6161 C CG2 . VAL D 4 316 ? -105.073 53.281  10.695  1.00 38.87  ? 452 VAL B CG2 1 
ATOM 6162 N N   . GLY D 4 317 ? -105.078 58.091  10.937  1.00 46.98  ? 453 GLY B N   1 
ATOM 6163 C CA  . GLY D 4 317 ? -104.470 59.413  10.904  1.00 51.95  ? 453 GLY B CA  1 
ATOM 6164 C C   . GLY D 4 317 ? -104.516 59.975  9.496   1.00 46.80  ? 453 GLY B C   1 
ATOM 6165 O O   . GLY D 4 317 ? -105.574 60.012  8.858   1.00 53.21  ? 453 GLY B O   1 
ATOM 6166 N N   . ASN D 4 318 ? -103.363 60.418  8.995   1.00 38.58  ? 454 ASN B N   1 
ATOM 6167 C CA  . ASN D 4 318 ? -103.257 60.933  7.637   1.00 52.78  ? 454 ASN B CA  1 
ATOM 6168 C C   . ASN D 4 318 ? -102.801 59.874  6.641   1.00 48.17  ? 454 ASN B C   1 
ATOM 6169 O O   . ASN D 4 318 ? -102.482 60.210  5.495   1.00 64.44  ? 454 ASN B O   1 
ATOM 6170 C CB  . ASN D 4 318 ? -102.310 62.135  7.585   1.00 51.92  ? 454 ASN B CB  1 
ATOM 6171 C CG  . ASN D 4 318 ? -102.736 63.254  8.510   1.00 47.02  ? 454 ASN B CG  1 
ATOM 6172 O OD1 . ASN D 4 318 ? -103.921 63.560  8.625   1.00 57.84  ? 454 ASN B OD1 1 
ATOM 6173 N ND2 . ASN D 4 318 ? -101.764 63.913  9.126   1.00 53.38  ? 454 ASN B ND2 1 
ATOM 6174 N N   . THR D 4 319 ? -102.764 58.611  7.048   1.00 44.49  ? 455 THR B N   1 
ATOM 6175 C CA  . THR D 4 319 ? -102.341 57.508  6.199   1.00 36.87  ? 455 THR B CA  1 
ATOM 6176 C C   . THR D 4 319 ? -103.557 56.694  5.782   1.00 51.27  ? 455 THR B C   1 
ATOM 6177 O O   . THR D 4 319 ? -104.341 56.259  6.633   1.00 38.51  ? 455 THR B O   1 
ATOM 6178 C CB  . THR D 4 319 ? -101.330 56.618  6.925   1.00 49.44  ? 455 THR B CB  1 
ATOM 6179 O OG1 . THR D 4 319 ? -100.207 57.407  7.339   1.00 64.34  ? 455 THR B OG1 1 
ATOM 6180 C CG2 . THR D 4 319 ? -100.862 55.489  6.026   1.00 38.46  ? 455 THR B CG2 1 
ATOM 6181 N N   . LEU D 4 320 ? -103.708 56.491  4.476   1.00 59.40  ? 456 LEU B N   1 
ATOM 6182 C CA  . LEU D 4 320 ? -104.818 55.738  3.912   1.00 42.89  ? 456 LEU B CA  1 
ATOM 6183 C C   . LEU D 4 320 ? -104.297 54.436  3.320   1.00 40.78  ? 456 LEU B C   1 
ATOM 6184 O O   . LEU D 4 320 ? -103.364 54.447  2.512   1.00 63.80  ? 456 LEU B O   1 
ATOM 6185 C CB  . LEU D 4 320 ? -105.542 56.562  2.848   1.00 57.69  ? 456 LEU B CB  1 
ATOM 6186 C CG  . LEU D 4 320 ? -106.778 55.944  2.196   1.00 47.82  ? 456 LEU B CG  1 
ATOM 6187 C CD1 . LEU D 4 320 ? -107.956 56.903  2.278   1.00 55.59  ? 456 LEU B CD1 1 
ATOM 6188 C CD2 . LEU D 4 320 ? -106.470 55.605  0.755   1.00 46.37  ? 456 LEU B CD2 1 
ATOM 6189 N N   . TYR D 4 321 ? -104.899 53.322  3.727   1.00 49.48  ? 457 TYR B N   1 
ATOM 6190 C CA  . TYR D 4 321 ? -104.502 51.990  3.292   1.00 42.08  ? 457 TYR B CA  1 
ATOM 6191 C C   . TYR D 4 321 ? -105.612 51.345  2.479   1.00 43.99  ? 457 TYR B C   1 
ATOM 6192 O O   . TYR D 4 321 ? -106.784 51.394  2.863   1.00 60.05  ? 457 TYR B O   1 
ATOM 6193 C CB  . TYR D 4 321 ? -104.180 51.084  4.485   1.00 40.61  ? 457 TYR B CB  1 
ATOM 6194 C CG  . TYR D 4 321 ? -102.950 51.462  5.277   1.00 56.81  ? 457 TYR B CG  1 
ATOM 6195 C CD1 . TYR D 4 321 ? -101.676 51.300  4.743   1.00 70.25  ? 457 TYR B CD1 1 
ATOM 6196 C CD2 . TYR D 4 321 ? -103.061 51.972  6.562   1.00 53.03  ? 457 TYR B CD2 1 
ATOM 6197 C CE1 . TYR D 4 321 ? -100.550 51.637  5.473   1.00 84.16  ? 457 TYR B CE1 1 
ATOM 6198 C CE2 . TYR D 4 321 ? -101.946 52.314  7.296   1.00 55.38  ? 457 TYR B CE2 1 
ATOM 6199 C CZ  . TYR D 4 321 ? -100.693 52.142  6.752   1.00 74.90  ? 457 TYR B CZ  1 
ATOM 6200 O OH  . TYR D 4 321 ? -99.582  52.488  7.491   1.00 69.08  ? 457 TYR B OH  1 
ATOM 6201 N N   . TYR D 4 322 ? -105.239 50.726  1.363   1.00 52.96  ? 458 TYR B N   1 
ATOM 6202 C CA  . TYR D 4 322 ? -106.154 49.865  0.630   1.00 49.06  ? 458 TYR B CA  1 
ATOM 6203 C C   . TYR D 4 322 ? -105.978 48.436  1.130   1.00 49.74  ? 458 TYR B C   1 
ATOM 6204 O O   . TYR D 4 322 ? -104.851 47.940  1.227   1.00 50.94  ? 458 TYR B O   1 
ATOM 6205 C CB  . TYR D 4 322 ? -105.910 49.940  -0.880  1.00 43.20  ? 458 TYR B CB  1 
ATOM 6206 C CG  . TYR D 4 322 ? -106.357 51.240  -1.519  1.00 48.54  ? 458 TYR B CG  1 
ATOM 6207 C CD1 . TYR D 4 322 ? -105.578 52.386  -1.429  1.00 58.41  ? 458 TYR B CD1 1 
ATOM 6208 C CD2 . TYR D 4 322 ? -107.572 51.328  -2.184  1.00 43.82  ? 458 TYR B CD2 1 
ATOM 6209 C CE1 . TYR D 4 322 ? -105.982 53.577  -2.013  1.00 42.74  ? 458 TYR B CE1 1 
ATOM 6210 C CE2 . TYR D 4 322 ? -107.989 52.518  -2.762  1.00 53.90  ? 458 TYR B CE2 1 
ATOM 6211 C CZ  . TYR D 4 322 ? -107.191 53.640  -2.670  1.00 51.51  ? 458 TYR B CZ  1 
ATOM 6212 O OH  . TYR D 4 322 ? -107.599 54.827  -3.241  1.00 52.65  ? 458 TYR B OH  1 
ATOM 6213 N N   . VAL D 4 323 ? -107.086 47.792  1.475   1.00 46.29  ? 459 VAL B N   1 
ATOM 6214 C CA  . VAL D 4 323 ? -107.042 46.407  1.924   1.00 45.82  ? 459 VAL B CA  1 
ATOM 6215 C C   . VAL D 4 323 ? -107.068 45.484  0.713   1.00 47.74  ? 459 VAL B C   1 
ATOM 6216 O O   . VAL D 4 323 ? -107.611 45.821  -0.345  1.00 52.11  ? 459 VAL B O   1 
ATOM 6217 C CB  . VAL D 4 323 ? -108.205 46.101  2.889   1.00 50.35  ? 459 VAL B CB  1 
ATOM 6218 C CG1 . VAL D 4 323 ? -108.060 46.911  4.169   1.00 55.52  ? 459 VAL B CG1 1 
ATOM 6219 C CG2 . VAL D 4 323 ? -109.540 46.375  2.222   1.00 52.35  ? 459 VAL B CG2 1 
ATOM 6220 N N   . ASN D 4 324 ? -106.458 44.312  0.868   1.00 55.43  ? 460 ASN B N   1 
ATOM 6221 C CA  . ASN D 4 324 ? -106.478 43.308  -0.185  1.00 46.92  ? 460 ASN B CA  1 
ATOM 6222 C C   . ASN D 4 324 ? -107.886 42.749  -0.353  1.00 46.06  ? 460 ASN B C   1 
ATOM 6223 O O   . ASN D 4 324 ? -108.593 42.499  0.627   1.00 49.20  ? 460 ASN B O   1 
ATOM 6224 C CB  . ASN D 4 324 ? -105.497 42.178  0.139   1.00 38.50  ? 460 ASN B CB  1 
ATOM 6225 C CG  . ASN D 4 324 ? -104.048 42.628  0.078   1.00 38.84  ? 460 ASN B CG  1 
ATOM 6226 O OD1 . ASN D 4 324 ? -103.637 43.310  -0.857  1.00 63.16  ? 460 ASN B OD1 1 
ATOM 6227 N ND2 . ASN D 4 324 ? -103.263 42.234  1.069   1.00 56.29  ? 460 ASN B ND2 1 
ATOM 6228 N N   . LYS D 4 325 ? -108.296 42.545  -1.606  1.00 48.81  ? 461 LYS B N   1 
ATOM 6229 C CA  . LYS D 4 325 ? -109.632 42.044  -1.901  1.00 53.96  ? 461 LYS B CA  1 
ATOM 6230 C C   . LYS D 4 325 ? -109.657 40.537  -2.141  1.00 46.49  ? 461 LYS B C   1 
ATOM 6231 O O   . LYS D 4 325 ? -110.613 40.027  -2.732  1.00 82.36  ? 461 LYS B O   1 
ATOM 6232 C CB  . LYS D 4 325 ? -110.226 42.784  -3.099  1.00 43.07  ? 461 LYS B CB  1 
ATOM 6233 C CG  . LYS D 4 325 ? -110.222 44.299  -2.959  1.00 35.47  ? 461 LYS B CG  1 
ATOM 6234 C CD  . LYS D 4 325 ? -111.061 44.761  -1.769  1.00 53.20  ? 461 LYS B CD  1 
ATOM 6235 C CE  . LYS D 4 325 ? -112.475 44.193  -1.796  1.00 67.26  ? 461 LYS B CE  1 
ATOM 6236 N NZ  . LYS D 4 325 ? -113.233 44.491  -0.542  1.00 44.75  ? 461 LYS B NZ  1 
ATOM 6237 N N   . GLN D 4 326 ? -108.640 39.817  -1.672  1.00 55.38  ? 462 GLN B N   1 
ATOM 6238 C CA  . GLN D 4 326 ? -108.582 38.374  -1.859  1.00 58.14  ? 462 GLN B CA  1 
ATOM 6239 C C   . GLN D 4 326 ? -109.786 37.704  -1.205  1.00 66.73  ? 462 GLN B C   1 
ATOM 6240 O O   . GLN D 4 326 ? -110.267 38.140  -0.157  1.00 82.78  ? 462 GLN B O   1 
ATOM 6241 C CB  . GLN D 4 326 ? -107.276 37.826  -1.271  1.00 63.70  ? 462 GLN B CB  1 
ATOM 6242 C CG  . GLN D 4 326 ? -107.204 36.309  -1.140  1.00 63.78  ? 462 GLN B CG  1 
ATOM 6243 C CD  . GLN D 4 326 ? -106.896 35.616  -2.457  1.00 92.85  ? 462 GLN B CD  1 
ATOM 6244 O OE1 . GLN D 4 326 ? -106.782 36.260  -3.502  1.00 111.44 ? 462 GLN B OE1 1 
ATOM 6245 N NE2 . GLN D 4 326 ? -106.758 34.295  -2.412  1.00 83.32  ? 462 GLN B NE2 1 
ATOM 6246 N N   . GLU D 4 327 ? -110.289 36.653  -1.847  1.00 80.50  ? 463 GLU B N   1 
ATOM 6247 C CA  . GLU D 4 327 ? -111.427 35.914  -1.320  1.00 81.34  ? 463 GLU B CA  1 
ATOM 6248 C C   . GLU D 4 327 ? -110.983 34.936  -0.238  1.00 71.79  ? 463 GLU B C   1 
ATOM 6249 O O   . GLU D 4 327 ? -109.971 34.244  -0.379  1.00 78.73  ? 463 GLU B O   1 
ATOM 6250 C CB  . GLU D 4 327 ? -112.141 35.165  -2.447  1.00 88.02  ? 463 GLU B CB  1 
ATOM 6251 C CG  . GLU D 4 327 ? -113.187 34.155  -1.986  1.00 101.17 ? 463 GLU B CG  1 
ATOM 6252 C CD  . GLU D 4 327 ? -114.315 34.788  -1.189  1.00 114.22 ? 463 GLU B CD  1 
ATOM 6253 O OE1 . GLU D 4 327 ? -114.136 35.018  0.029   1.00 99.73  ? 463 GLU B OE1 1 
ATOM 6254 O OE2 . GLU D 4 327 ? -115.381 35.059  -1.782  1.00 122.75 ? 463 GLU B OE2 1 
ATOM 6255 N N   . GLY D 4 328 ? -111.750 34.885  0.844   1.00 71.29  ? 464 GLY B N   1 
ATOM 6256 C CA  . GLY D 4 328 ? -111.453 33.982  1.940   1.00 75.56  ? 464 GLY B CA  1 
ATOM 6257 C C   . GLY D 4 328 ? -112.311 34.312  3.138   1.00 61.12  ? 464 GLY B C   1 
ATOM 6258 O O   . GLY D 4 328 ? -113.017 35.322  3.172   1.00 76.23  ? 464 GLY B O   1 
ATOM 6259 N N   . LYS D 4 329 ? -112.230 33.439  4.138   1.00 65.27  ? 465 LYS B N   1 
ATOM 6260 C CA  . LYS D 4 329 ? -113.025 33.558  5.353   1.00 73.38  ? 465 LYS B CA  1 
ATOM 6261 C C   . LYS D 4 329 ? -112.161 34.057  6.505   1.00 64.02  ? 465 LYS B C   1 
ATOM 6262 O O   . LYS D 4 329 ? -111.047 33.567  6.716   1.00 64.38  ? 465 LYS B O   1 
ATOM 6263 C CB  . LYS D 4 329 ? -113.661 32.216  5.727   1.00 78.95  ? 465 LYS B CB  1 
ATOM 6264 C CG  . LYS D 4 329 ? -114.485 32.260  7.006   1.00 100.64 ? 465 LYS B CG  1 
ATOM 6265 C CD  . LYS D 4 329 ? -115.124 30.913  7.310   1.00 107.87 ? 465 LYS B CD  1 
ATOM 6266 C CE  . LYS D 4 329 ? -114.136 29.969  7.979   1.00 104.98 ? 465 LYS B CE  1 
ATOM 6267 N NZ  . LYS D 4 329 ? -114.772 28.672  8.347   1.00 97.69  ? 465 LYS B NZ  1 
ATOM 6268 N N   . SER D 4 330 ? -112.683 35.027  7.251   1.00 62.61  ? 466 SER B N   1 
ATOM 6269 C CA  . SER D 4 330 ? -111.985 35.619  8.381   1.00 65.35  ? 466 SER B CA  1 
ATOM 6270 C C   . SER D 4 330 ? -112.728 35.301  9.674   1.00 54.27  ? 466 SER B C   1 
ATOM 6271 O O   . SER D 4 330 ? -113.951 35.137  9.680   1.00 65.87  ? 466 SER B O   1 
ATOM 6272 C CB  . SER D 4 330 ? -111.851 37.138  8.209   1.00 59.93  ? 466 SER B CB  1 
ATOM 6273 O OG  . SER D 4 330 ? -110.814 37.655  9.020   1.00 78.45  ? 466 SER B OG  1 
ATOM 6274 N N   . LEU D 4 331 ? -111.979 35.212  10.772  1.00 58.14  ? 467 LEU B N   1 
ATOM 6275 C CA  . LEU D 4 331 ? -112.549 34.866  12.069  1.00 63.70  ? 467 LEU B CA  1 
ATOM 6276 C C   . LEU D 4 331 ? -111.968 35.763  13.152  1.00 58.44  ? 467 LEU B C   1 
ATOM 6277 O O   . LEU D 4 331 ? -110.746 35.848  13.299  1.00 60.36  ? 467 LEU B O   1 
ATOM 6278 C CB  . LEU D 4 331 ? -112.281 33.398  12.411  1.00 67.09  ? 467 LEU B CB  1 
ATOM 6279 C CG  . LEU D 4 331 ? -112.895 32.894  13.714  1.00 64.89  ? 467 LEU B CG  1 
ATOM 6280 C CD1 . LEU D 4 331 ? -114.411 32.957  13.624  1.00 64.91  ? 467 LEU B CD1 1 
ATOM 6281 C CD2 . LEU D 4 331 ? -112.429 31.478  14.001  1.00 74.46  ? 467 LEU B CD2 1 
ATOM 6282 N N   . TYR D 4 332 ? -112.844 36.413  13.915  1.00 60.62  ? 468 TYR B N   1 
ATOM 6283 C CA  . TYR D 4 332 ? -112.441 37.249  15.041  1.00 61.52  ? 468 TYR B CA  1 
ATOM 6284 C C   . TYR D 4 332 ? -112.472 36.415  16.318  1.00 54.52  ? 468 TYR B C   1 
ATOM 6285 O O   . TYR D 4 332 ? -113.517 35.861  16.677  1.00 65.71  ? 468 TYR B O   1 
ATOM 6286 C CB  . TYR D 4 332 ? -113.367 38.460  15.164  1.00 52.47  ? 468 TYR B CB  1 
ATOM 6287 C CG  . TYR D 4 332 ? -112.854 39.580  16.049  1.00 52.83  ? 468 TYR B CG  1 
ATOM 6288 C CD1 . TYR D 4 332 ? -112.739 39.409  17.426  1.00 62.46  ? 468 TYR B CD1 1 
ATOM 6289 C CD2 . TYR D 4 332 ? -112.527 40.821  15.514  1.00 52.22  ? 468 TYR B CD2 1 
ATOM 6290 C CE1 . TYR D 4 332 ? -112.285 40.431  18.241  1.00 55.07  ? 468 TYR B CE1 1 
ATOM 6291 C CE2 . TYR D 4 332 ? -112.074 41.853  16.325  1.00 57.48  ? 468 TYR B CE2 1 
ATOM 6292 C CZ  . TYR D 4 332 ? -111.956 41.649  17.687  1.00 61.06  ? 468 TYR B CZ  1 
ATOM 6293 O OH  . TYR D 4 332 ? -111.507 42.663  18.498  1.00 73.88  ? 468 TYR B OH  1 
ATOM 6294 N N   . VAL D 4 333 ? -111.338 36.342  17.012  1.00 54.81  ? 469 VAL B N   1 
ATOM 6295 C CA  . VAL D 4 333 ? -111.201 35.543  18.228  1.00 59.91  ? 469 VAL B CA  1 
ATOM 6296 C C   . VAL D 4 333 ? -111.119 36.500  19.410  1.00 47.63  ? 469 VAL B C   1 
ATOM 6297 O O   . VAL D 4 333 ? -110.077 37.123  19.647  1.00 59.37  ? 469 VAL B O   1 
ATOM 6298 C CB  . VAL D 4 333 ? -109.971 34.628  18.173  1.00 53.13  ? 469 VAL B CB  1 
ATOM 6299 C CG1 . VAL D 4 333 ? -109.855 33.824  19.454  1.00 36.39  ? 469 VAL B CG1 1 
ATOM 6300 C CG2 . VAL D 4 333 ? -110.037 33.715  16.956  1.00 56.44  ? 469 VAL B CG2 1 
ATOM 6301 N N   . LYS D 4 334 ? -112.208 36.600  20.169  1.00 70.77  ? 470 LYS B N   1 
ATOM 6302 C CA  . LYS D 4 334 ? -112.299 37.576  21.247  1.00 62.76  ? 470 LYS B CA  1 
ATOM 6303 C C   . LYS D 4 334 ? -111.398 37.202  22.421  1.00 56.90  ? 470 LYS B C   1 
ATOM 6304 O O   . LYS D 4 334 ? -111.204 36.026  22.741  1.00 53.13  ? 470 LYS B O   1 
ATOM 6305 C CB  . LYS D 4 334 ? -113.743 37.701  21.731  1.00 61.90  ? 470 LYS B CB  1 
ATOM 6306 C CG  . LYS D 4 334 ? -114.715 38.178  20.669  1.00 67.31  ? 470 LYS B CG  1 
ATOM 6307 C CD  . LYS D 4 334 ? -115.671 39.220  21.213  1.00 62.72  ? 470 LYS B CD  1 
ATOM 6308 C CE  . LYS D 4 334 ? -117.011 38.590  21.566  1.00 89.63  ? 470 LYS B CE  1 
ATOM 6309 N NZ  . LYS D 4 334 ? -117.641 37.902  20.404  1.00 69.47  ? 470 LYS B NZ  1 
ATOM 6310 N N   . GLY D 4 335 ? -110.857 38.224  23.069  1.00 55.83  ? 471 GLY B N   1 
ATOM 6311 C CA  . GLY D 4 335 ? -110.031 38.016  24.242  1.00 52.35  ? 471 GLY B CA  1 
ATOM 6312 C C   . GLY D 4 335 ? -109.603 39.346  24.826  1.00 62.41  ? 471 GLY B C   1 
ATOM 6313 O O   . GLY D 4 335 ? -109.578 40.375  24.142  1.00 65.38  ? 471 GLY B O   1 
ATOM 6314 N N   . GLU D 4 336 ? -109.266 39.303  26.108  1.00 64.73  ? 472 GLU B N   1 
ATOM 6315 C CA  . GLU D 4 336 ? -108.808 40.504  26.797  1.00 61.51  ? 472 GLU B CA  1 
ATOM 6316 C C   . GLU D 4 336 ? -107.369 40.818  26.402  1.00 63.60  ? 472 GLU B C   1 
ATOM 6317 O O   . GLU D 4 336 ? -106.520 39.920  26.420  1.00 51.46  ? 472 GLU B O   1 
ATOM 6318 C CB  . GLU D 4 336 ? -108.904 40.328  28.306  1.00 63.17  ? 472 GLU B CB  1 
ATOM 6319 C CG  . GLU D 4 336 ? -108.390 41.518  29.093  1.00 68.42  ? 472 GLU B CG  1 
ATOM 6320 C CD  . GLU D 4 336 ? -108.644 41.379  30.578  1.00 86.01  ? 472 GLU B CD  1 
ATOM 6321 O OE1 . GLU D 4 336 ? -109.165 40.321  30.994  1.00 91.13  ? 472 GLU B OE1 1 
ATOM 6322 O OE2 . GLU D 4 336 ? -108.321 42.323  31.329  1.00 91.41  ? 472 GLU B OE2 1 
ATOM 6323 N N   . PRO D 4 337 ? -107.062 42.065  26.037  1.00 61.74  ? 473 PRO B N   1 
ATOM 6324 C CA  . PRO D 4 337 ? -105.675 42.424  25.711  1.00 50.32  ? 473 PRO B CA  1 
ATOM 6325 C C   . PRO D 4 337 ? -104.739 42.111  26.868  1.00 54.18  ? 473 PRO B C   1 
ATOM 6326 O O   . PRO D 4 337 ? -104.983 42.508  28.010  1.00 69.95  ? 473 PRO B O   1 
ATOM 6327 C CB  . PRO D 4 337 ? -105.756 43.931  25.447  1.00 48.62  ? 473 PRO B CB  1 
ATOM 6328 C CG  . PRO D 4 337 ? -107.164 44.156  25.021  1.00 53.42  ? 473 PRO B CG  1 
ATOM 6329 C CD  . PRO D 4 337 ? -107.986 43.191  25.826  1.00 59.62  ? 473 PRO B CD  1 
ATOM 6330 N N   . ILE D 4 338 ? -103.645 41.411  26.558  1.00 47.02  ? 474 ILE B N   1 
ATOM 6331 C CA  . ILE D 4 338 ? -102.734 40.971  27.607  1.00 59.63  ? 474 ILE B CA  1 
ATOM 6332 C C   . ILE D 4 338 ? -102.014 42.140  28.266  1.00 59.82  ? 474 ILE B C   1 
ATOM 6333 O O   . ILE D 4 338 ? -101.531 42.002  29.397  1.00 64.60  ? 474 ILE B O   1 
ATOM 6334 C CB  . ILE D 4 338 ? -101.723 39.949  27.053  1.00 47.38  ? 474 ILE B CB  1 
ATOM 6335 C CG1 . ILE D 4 338 ? -100.684 40.643  26.170  1.00 56.56  ? 474 ILE B CG1 1 
ATOM 6336 C CG2 . ILE D 4 338 ? -102.448 38.864  26.277  1.00 50.04  ? 474 ILE B CG2 1 
ATOM 6337 C CD1 . ILE D 4 338 ? -99.551  39.734  25.733  1.00 54.47  ? 474 ILE B CD1 1 
ATOM 6338 N N   . ILE D 4 339 ? -101.943 43.299  27.602  1.00 47.38  ? 475 ILE B N   1 
ATOM 6339 C CA  . ILE D 4 339 ? -101.303 44.461  28.209  1.00 55.70  ? 475 ILE B CA  1 
ATOM 6340 C C   . ILE D 4 339 ? -102.052 44.927  29.451  1.00 59.26  ? 475 ILE B C   1 
ATOM 6341 O O   . ILE D 4 339 ? -101.466 45.605  30.305  1.00 67.87  ? 475 ILE B O   1 
ATOM 6342 C CB  . ILE D 4 339 ? -101.167 45.604  27.183  1.00 52.35  ? 475 ILE B CB  1 
ATOM 6343 C CG1 . ILE D 4 339 ? -100.133 46.634  27.651  1.00 47.02  ? 475 ILE B CG1 1 
ATOM 6344 C CG2 . ILE D 4 339 ? -102.510 46.273  26.934  1.00 60.83  ? 475 ILE B CG2 1 
ATOM 6345 C CD1 . ILE D 4 339 ? -98.702  46.143  27.596  1.00 38.84  ? 475 ILE B CD1 1 
ATOM 6346 N N   . ASN D 4 340 ? -103.333 44.567  29.585  1.00 68.27  ? 476 ASN B N   1 
ATOM 6347 C CA  . ASN D 4 340 ? -104.093 44.927  30.778  1.00 68.51  ? 476 ASN B CA  1 
ATOM 6348 C C   . ASN D 4 340 ? -103.554 44.247  32.030  1.00 55.82  ? 476 ASN B C   1 
ATOM 6349 O O   . ASN D 4 340 ? -103.710 44.778  33.134  1.00 69.25  ? 476 ASN B O   1 
ATOM 6350 C CB  . ASN D 4 340 ? -105.567 44.570  30.589  1.00 65.89  ? 476 ASN B CB  1 
ATOM 6351 C CG  . ASN D 4 340 ? -106.269 45.501  29.629  1.00 66.61  ? 476 ASN B CG  1 
ATOM 6352 O OD1 . ASN D 4 340 ? -105.664 46.432  29.097  1.00 81.33  ? 476 ASN B OD1 1 
ATOM 6353 N ND2 . ASN D 4 340 ? -107.552 45.251  29.392  1.00 69.04  ? 476 ASN B ND2 1 
ATOM 6354 N N   . PHE D 4 341 ? -102.918 43.085  31.881  1.00 59.76  ? 477 PHE B N   1 
ATOM 6355 C CA  . PHE D 4 341 ? -102.469 42.293  33.020  1.00 59.34  ? 477 PHE B CA  1 
ATOM 6356 C C   . PHE D 4 341 ? -101.201 42.832  33.669  1.00 52.58  ? 477 PHE B C   1 
ATOM 6357 O O   . PHE D 4 341 ? -100.839 42.371  34.756  1.00 78.90  ? 477 PHE B O   1 
ATOM 6358 C CB  . PHE D 4 341 ? -102.225 40.841  32.593  1.00 54.44  ? 477 PHE B CB  1 
ATOM 6359 C CG  . PHE D 4 341 ? -103.441 40.148  32.038  1.00 70.76  ? 477 PHE B CG  1 
ATOM 6360 C CD1 . PHE D 4 341 ? -104.716 40.634  32.284  1.00 71.43  ? 477 PHE B CD1 1 
ATOM 6361 C CD2 . PHE D 4 341 ? -103.305 39.004  31.269  1.00 69.12  ? 477 PHE B CD2 1 
ATOM 6362 C CE1 . PHE D 4 341 ? -105.827 39.993  31.770  1.00 76.74  ? 477 PHE B CE1 1 
ATOM 6363 C CE2 . PHE D 4 341 ? -104.412 38.358  30.755  1.00 70.95  ? 477 PHE B CE2 1 
ATOM 6364 C CZ  . PHE D 4 341 ? -105.676 38.853  31.005  1.00 75.88  ? 477 PHE B CZ  1 
ATOM 6365 N N   . TYR D 4 342 ? -100.522 43.786  33.043  1.00 55.05  ? 478 TYR B N   1 
ATOM 6366 C CA  . TYR D 4 342 ? -99.206  44.229  33.481  1.00 64.66  ? 478 TYR B CA  1 
ATOM 6367 C C   . TYR D 4 342 ? -99.319  45.509  34.301  1.00 67.90  ? 478 TYR B C   1 
ATOM 6368 O O   . TYR D 4 342 ? -99.991  46.461  33.890  1.00 72.45  ? 478 TYR B O   1 
ATOM 6369 C CB  . TYR D 4 342 ? -98.283  44.438  32.276  1.00 65.13  ? 478 TYR B CB  1 
ATOM 6370 C CG  . TYR D 4 342 ? -97.823  43.137  31.650  1.00 47.82  ? 478 TYR B CG  1 
ATOM 6371 C CD1 . TYR D 4 342 ? -98.650  42.417  30.798  1.00 49.30  ? 478 TYR B CD1 1 
ATOM 6372 C CD2 . TYR D 4 342 ? -96.570  42.616  31.936  1.00 46.19  ? 478 TYR B CD2 1 
ATOM 6373 C CE1 . TYR D 4 342 ? -98.234  41.221  30.238  1.00 58.74  ? 478 TYR B CE1 1 
ATOM 6374 C CE2 . TYR D 4 342 ? -96.145  41.424  31.384  1.00 53.03  ? 478 TYR B CE2 1 
ATOM 6375 C CZ  . TYR D 4 342 ? -96.979  40.729  30.535  1.00 60.81  ? 478 TYR B CZ  1 
ATOM 6376 O OH  . TYR D 4 342 ? -96.554  39.538  29.984  1.00 61.98  ? 478 TYR B OH  1 
ATOM 6377 N N   . ASP D 4 343 ? -98.666  45.521  35.460  1.00 64.04  ? 479 ASP B N   1 
ATOM 6378 C CA  . ASP D 4 343 ? -98.616  46.717  36.291  1.00 58.58  ? 479 ASP B CA  1 
ATOM 6379 C C   . ASP D 4 343 ? -97.597  47.685  35.700  1.00 56.66  ? 479 ASP B C   1 
ATOM 6380 O O   . ASP D 4 343 ? -96.417  47.333  35.592  1.00 67.20  ? 479 ASP B O   1 
ATOM 6381 C CB  . ASP D 4 343 ? -98.240  46.351  37.726  1.00 84.59  ? 479 ASP B CB  1 
ATOM 6382 C CG  . ASP D 4 343 ? -98.374  47.522  38.700  1.00 86.24  ? 479 ASP B CG  1 
ATOM 6383 O OD1 . ASP D 4 343 ? -98.399  48.694  38.268  1.00 73.06  ? 479 ASP B OD1 1 
ATOM 6384 O OD2 . ASP D 4 343 ? -98.446  47.260  39.920  1.00 102.70 ? 479 ASP B OD2 1 
ATOM 6385 N N   . PRO D 4 344 ? -98.003  48.893  35.306  1.00 52.48  ? 480 PRO B N   1 
ATOM 6386 C CA  . PRO D 4 344 ? -97.047  49.824  34.679  1.00 61.37  ? 480 PRO B CA  1 
ATOM 6387 C C   . PRO D 4 344 ? -95.886  50.228  35.574  1.00 70.01  ? 480 PRO B C   1 
ATOM 6388 O O   . PRO D 4 344 ? -94.822  50.592  35.056  1.00 74.22  ? 480 PRO B O   1 
ATOM 6389 C CB  . PRO D 4 344 ? -97.924  51.032  34.321  1.00 46.56  ? 480 PRO B CB  1 
ATOM 6390 C CG  . PRO D 4 344 ? -99.310  50.479  34.219  1.00 54.37  ? 480 PRO B CG  1 
ATOM 6391 C CD  . PRO D 4 344 ? -99.391  49.378  35.233  1.00 40.19  ? 480 PRO B CD  1 
ATOM 6392 N N   . LEU D 4 345 ? -96.056  50.187  36.899  1.00 75.72  ? 481 LEU B N   1 
ATOM 6393 C CA  . LEU D 4 345 ? -95.001  50.640  37.803  1.00 77.18  ? 481 LEU B CA  1 
ATOM 6394 C C   . LEU D 4 345 ? -93.763  49.754  37.718  1.00 73.77  ? 481 LEU B C   1 
ATOM 6395 O O   . LEU D 4 345 ? -92.633  50.254  37.747  1.00 86.92  ? 481 LEU B O   1 
ATOM 6396 C CB  . LEU D 4 345 ? -95.526  50.687  39.238  1.00 94.52  ? 481 LEU B CB  1 
ATOM 6397 C CG  . LEU D 4 345 ? -96.901  51.328  39.434  1.00 88.73  ? 481 LEU B CG  1 
ATOM 6398 C CD1 . LEU D 4 345 ? -97.407  51.098  40.851  1.00 79.83  ? 481 LEU B CD1 1 
ATOM 6399 C CD2 . LEU D 4 345 ? -96.848  52.815  39.111  1.00 83.23  ? 481 LEU B CD2 1 
ATOM 6400 N N   . VAL D 4 346 ? -93.952  48.441  37.625  1.00 66.68  ? 482 VAL B N   1 
ATOM 6401 C CA  . VAL D 4 346 ? -92.846  47.497  37.543  1.00 73.36  ? 482 VAL B CA  1 
ATOM 6402 C C   . VAL D 4 346 ? -92.720  46.905  36.139  1.00 74.45  ? 482 VAL B C   1 
ATOM 6403 O O   . VAL D 4 346 ? -92.172  45.815  35.974  1.00 71.11  ? 482 VAL B O   1 
ATOM 6404 C CB  . VAL D 4 346 ? -92.980  46.391  38.602  1.00 67.55  ? 482 VAL B CB  1 
ATOM 6405 C CG1 . VAL D 4 346 ? -92.497  46.887  39.956  1.00 72.45  ? 482 VAL B CG1 1 
ATOM 6406 C CG2 . VAL D 4 346 ? -94.422  45.912  38.686  1.00 60.14  ? 482 VAL B CG2 1 
ATOM 6407 N N   . PHE D 4 347 ? -93.217  47.610  35.123  1.00 66.24  ? 483 PHE B N   1 
ATOM 6408 C CA  . PHE D 4 347 ? -93.234  47.087  33.762  1.00 54.94  ? 483 PHE B CA  1 
ATOM 6409 C C   . PHE D 4 347 ? -91.939  47.451  33.046  1.00 51.68  ? 483 PHE B C   1 
ATOM 6410 O O   . PHE D 4 347 ? -91.642  48.644  32.899  1.00 59.70  ? 483 PHE B O   1 
ATOM 6411 C CB  . PHE D 4 347 ? -94.425  47.637  32.995  1.00 66.61  ? 483 PHE B CB  1 
ATOM 6412 C CG  . PHE D 4 347 ? -94.529  47.133  31.582  1.00 64.24  ? 483 PHE B CG  1 
ATOM 6413 C CD1 . PHE D 4 347 ? -95.099  45.898  31.312  1.00 57.20  ? 483 PHE B CD1 1 
ATOM 6414 C CD2 . PHE D 4 347 ? -94.073  47.901  30.521  1.00 50.95  ? 483 PHE B CD2 1 
ATOM 6415 C CE1 . PHE D 4 347 ? -95.200  45.434  30.012  1.00 59.72  ? 483 PHE B CE1 1 
ATOM 6416 C CE2 . PHE D 4 347 ? -94.174  47.442  29.221  1.00 50.55  ? 483 PHE B CE2 1 
ATOM 6417 C CZ  . PHE D 4 347 ? -94.740  46.208  28.965  1.00 45.39  ? 483 PHE B CZ  1 
ATOM 6418 N N   . PRO D 4 348 ? -91.148  46.475  32.588  1.00 42.51  ? 484 PRO B N   1 
ATOM 6419 C CA  . PRO D 4 348 ? -89.939  46.803  31.819  1.00 64.76  ? 484 PRO B CA  1 
ATOM 6420 C C   . PRO D 4 348 ? -90.288  47.329  30.434  1.00 68.42  ? 484 PRO B C   1 
ATOM 6421 O O   . PRO D 4 348 ? -90.750  46.574  29.574  1.00 62.26  ? 484 PRO B O   1 
ATOM 6422 C CB  . PRO D 4 348 ? -89.193  45.465  31.752  1.00 61.03  ? 484 PRO B CB  1 
ATOM 6423 C CG  . PRO D 4 348 ? -90.273  44.434  31.860  1.00 56.56  ? 484 PRO B CG  1 
ATOM 6424 C CD  . PRO D 4 348 ? -91.316  45.022  32.773  1.00 56.39  ? 484 PRO B CD  1 
ATOM 6425 N N   . SER D 4 349 ? -90.066  48.622  30.203  1.00 66.54  ? 485 SER B N   1 
ATOM 6426 C CA  . SER D 4 349 ? -90.629  49.308  29.047  1.00 64.58  ? 485 SER B CA  1 
ATOM 6427 C C   . SER D 4 349 ? -89.612  49.597  27.949  1.00 77.64  ? 485 SER B C   1 
ATOM 6428 O O   . SER D 4 349 ? -89.920  50.363  27.029  1.00 82.71  ? 485 SER B O   1 
ATOM 6429 C CB  . SER D 4 349 ? -91.302  50.608  29.493  1.00 73.93  ? 485 SER B CB  1 
ATOM 6430 O OG  . SER D 4 349 ? -90.356  51.524  30.018  1.00 92.09  ? 485 SER B OG  1 
ATOM 6431 N N   . ASP D 4 350 ? -88.412  49.023  28.016  1.00 80.50  ? 486 ASP B N   1 
ATOM 6432 C CA  . ASP D 4 350 ? -87.440  49.146  26.929  1.00 74.63  ? 486 ASP B CA  1 
ATOM 6433 C C   . ASP D 4 350 ? -86.793  47.798  26.627  1.00 65.06  ? 486 ASP B C   1 
ATOM 6434 O O   . ASP D 4 350 ? -85.571  47.674  26.528  1.00 72.24  ? 486 ASP B O   1 
ATOM 6435 C CB  . ASP D 4 350 ? -86.379  50.201  27.226  1.00 89.78  ? 486 ASP B CB  1 
ATOM 6436 C CG  . ASP D 4 350 ? -86.060  51.044  26.008  1.00 106.48 ? 486 ASP B CG  1 
ATOM 6437 O OD1 . ASP D 4 350 ? -86.875  51.028  25.062  1.00 113.15 ? 486 ASP B OD1 1 
ATOM 6438 O OD2 . ASP D 4 350 ? -85.001  51.702  25.978  1.00 109.99 ? 486 ASP B OD2 1 
ATOM 6439 N N   . GLU D 4 351 ? -87.615  46.766  26.481  1.00 62.75  ? 487 GLU B N   1 
ATOM 6440 C CA  . GLU D 4 351 ? -87.143  45.426  26.145  1.00 68.52  ? 487 GLU B CA  1 
ATOM 6441 C C   . GLU D 4 351 ? -87.255  45.283  24.628  1.00 76.60  ? 487 GLU B C   1 
ATOM 6442 O O   . GLU D 4 351 ? -88.330  44.988  24.100  1.00 73.02  ? 487 GLU B O   1 
ATOM 6443 C CB  . GLU D 4 351 ? -87.965  44.370  26.875  1.00 71.22  ? 487 GLU B CB  1 
ATOM 6444 C CG  . GLU D 4 351 ? -87.873  44.428  28.397  1.00 78.30  ? 487 GLU B CG  1 
ATOM 6445 C CD  . GLU D 4 351 ? -86.460  44.294  28.928  1.00 81.70  ? 487 GLU B CD  1 
ATOM 6446 O OE1 . GLU D 4 351 ? -85.687  43.473  28.395  1.00 83.65  ? 487 GLU B OE1 1 
ATOM 6447 O OE2 . GLU D 4 351 ? -86.122  45.019  29.886  1.00 96.21  ? 487 GLU B OE2 1 
ATOM 6448 N N   . PHE D 4 352 ? -86.142  45.506  23.921  1.00 77.03  ? 488 PHE B N   1 
ATOM 6449 C CA  . PHE D 4 352 ? -86.192  45.527  22.461  1.00 76.41  ? 488 PHE B CA  1 
ATOM 6450 C C   . PHE D 4 352 ? -86.316  44.127  21.867  1.00 80.02  ? 488 PHE B C   1 
ATOM 6451 O O   . PHE D 4 352 ? -87.104  43.916  20.939  1.00 76.08  ? 488 PHE B O   1 
ATOM 6452 C CB  . PHE D 4 352 ? -84.957  46.230  21.897  1.00 82.96  ? 488 PHE B CB  1 
ATOM 6453 C CG  . PHE D 4 352 ? -85.172  46.821  20.533  1.00 88.87  ? 488 PHE B CG  1 
ATOM 6454 C CD1 . PHE D 4 352 ? -85.841  48.025  20.383  1.00 87.53  ? 488 PHE B CD1 1 
ATOM 6455 C CD2 . PHE D 4 352 ? -84.719  46.166  19.399  1.00 89.84  ? 488 PHE B CD2 1 
ATOM 6456 C CE1 . PHE D 4 352 ? -86.045  48.570  19.130  1.00 99.42  ? 488 PHE B CE1 1 
ATOM 6457 C CE2 . PHE D 4 352 ? -84.921  46.706  18.143  1.00 89.16  ? 488 PHE B CE2 1 
ATOM 6458 C CZ  . PHE D 4 352 ? -85.585  47.909  18.008  1.00 93.63  ? 488 PHE B CZ  1 
ATOM 6459 N N   . ASP D 4 353 ? -85.547  43.161  22.376  1.00 81.13  ? 489 ASP B N   1 
ATOM 6460 C CA  . ASP D 4 353 ? -85.585  41.776  21.893  1.00 85.97  ? 489 ASP B CA  1 
ATOM 6461 C C   . ASP D 4 353 ? -85.789  40.881  23.112  1.00 79.29  ? 489 ASP B C   1 
ATOM 6462 O O   . ASP D 4 353 ? -84.833  40.331  23.663  1.00 90.70  ? 489 ASP B O   1 
ATOM 6463 C CB  . ASP D 4 353 ? -84.305  41.422  21.128  1.00 101.45 ? 489 ASP B CB  1 
ATOM 6464 C CG  . ASP D 4 353 ? -84.318  40.002  20.590  1.00 103.60 ? 489 ASP B CG  1 
ATOM 6465 O OD1 . ASP D 4 353 ? -85.417  39.420  20.472  1.00 101.42 ? 489 ASP B OD1 1 
ATOM 6466 O OD2 . ASP D 4 353 ? -83.229  39.462  20.299  1.00 104.86 ? 489 ASP B OD2 1 
ATOM 6467 N N   . ALA D 4 354 ? -87.046  40.713  23.516  1.00 75.32  ? 490 ALA B N   1 
ATOM 6468 C CA  . ALA D 4 354 ? -87.347  40.012  24.756  1.00 70.86  ? 490 ALA B CA  1 
ATOM 6469 C C   . ALA D 4 354 ? -88.343  38.883  24.542  1.00 66.91  ? 490 ALA B C   1 
ATOM 6470 O O   . ALA D 4 354 ? -88.665  38.531  23.403  1.00 68.23  ? 490 ALA B O   1 
ATOM 6471 C CB  . ALA D 4 354 ? -87.883  40.987  25.804  1.00 68.90  ? 490 ALA B CB  1 
ATOM 6472 N N   . SER D 4 355 ? -88.833  38.311  25.637  1.00 65.06  ? 491 SER B N   1 
ATOM 6473 C CA  . SER D 4 355 ? -89.763  37.196  25.571  1.00 71.59  ? 491 SER B CA  1 
ATOM 6474 C C   . SER D 4 355 ? -90.712  37.277  26.757  1.00 74.40  ? 491 SER B C   1 
ATOM 6475 O O   . SER D 4 355 ? -90.511  38.062  27.687  1.00 70.72  ? 491 SER B O   1 
ATOM 6476 C CB  . SER D 4 355 ? -89.021  35.857  25.546  1.00 76.87  ? 491 SER B CB  1 
ATOM 6477 O OG  . SER D 4 355 ? -87.948  35.851  26.471  1.00 87.75  ? 491 SER B OG  1 
ATOM 6478 N N   . ILE D 4 356 ? -91.761  36.453  26.708  1.00 71.53  ? 492 ILE B N   1 
ATOM 6479 C CA  . ILE D 4 356 ? -92.760  36.458  27.774  1.00 76.85  ? 492 ILE B CA  1 
ATOM 6480 C C   . ILE D 4 356 ? -92.118  36.081  29.103  1.00 79.15  ? 492 ILE B C   1 
ATOM 6481 O O   . ILE D 4 356 ? -92.336  36.739  30.128  1.00 74.17  ? 492 ILE B O   1 
ATOM 6482 C CB  . ILE D 4 356 ? -93.925  35.516  27.422  1.00 67.33  ? 492 ILE B CB  1 
ATOM 6483 C CG1 . ILE D 4 356 ? -94.775  36.117  26.303  1.00 69.28  ? 492 ILE B CG1 1 
ATOM 6484 C CG2 . ILE D 4 356 ? -94.783  35.246  28.650  1.00 69.97  ? 492 ILE B CG2 1 
ATOM 6485 C CD1 . ILE D 4 356 ? -95.553  37.342  26.720  1.00 64.02  ? 492 ILE B CD1 1 
ATOM 6486 N N   . SER D 4 357 ? -91.309  35.019  29.102  1.00 84.25  ? 493 SER B N   1 
ATOM 6487 C CA  . SER D 4 357 ? -90.639  34.597  30.328  1.00 75.83  ? 493 SER B CA  1 
ATOM 6488 C C   . SER D 4 357 ? -89.640  35.643  30.805  1.00 70.18  ? 493 SER B C   1 
ATOM 6489 O O   . SER D 4 357 ? -89.555  35.924  32.006  1.00 74.70  ? 493 SER B O   1 
ATOM 6490 C CB  . SER D 4 357 ? -89.947  33.253  30.109  1.00 85.53  ? 493 SER B CB  1 
ATOM 6491 O OG  . SER D 4 357 ? -90.862  32.285  29.624  1.00 101.13 ? 493 SER B OG  1 
ATOM 6492 N N   . GLN D 4 358 ? -88.879  36.232  29.880  1.00 67.64  ? 494 GLN B N   1 
ATOM 6493 C CA  . GLN D 4 358 ? -87.885  37.227  30.269  1.00 74.20  ? 494 GLN B CA  1 
ATOM 6494 C C   . GLN D 4 358 ? -88.541  38.442  30.913  1.00 68.55  ? 494 GLN B C   1 
ATOM 6495 O O   . GLN D 4 358 ? -88.037  38.973  31.910  1.00 74.55  ? 494 GLN B O   1 
ATOM 6496 C CB  . GLN D 4 358 ? -87.058  37.645  29.056  1.00 78.97  ? 494 GLN B CB  1 
ATOM 6497 C CG  . GLN D 4 358 ? -85.864  38.516  29.394  1.00 78.00  ? 494 GLN B CG  1 
ATOM 6498 C CD  . GLN D 4 358 ? -84.916  38.664  28.226  1.00 90.29  ? 494 GLN B CD  1 
ATOM 6499 O OE1 . GLN D 4 358 ? -85.158  38.126  27.144  1.00 83.21  ? 494 GLN B OE1 1 
ATOM 6500 N NE2 . GLN D 4 358 ? -83.829  39.398  28.435  1.00 94.07  ? 494 GLN B NE2 1 
ATOM 6501 N N   . VAL D 4 359 ? -89.661  38.901  30.352  1.00 73.42  ? 495 VAL B N   1 
ATOM 6502 C CA  . VAL D 4 359 ? -90.387  40.022  30.945  1.00 80.55  ? 495 VAL B CA  1 
ATOM 6503 C C   . VAL D 4 359 ? -90.938  39.636  32.313  1.00 68.67  ? 495 VAL B C   1 
ATOM 6504 O O   . VAL D 4 359 ? -90.882  40.422  33.267  1.00 64.65  ? 495 VAL B O   1 
ATOM 6505 C CB  . VAL D 4 359 ? -91.498  40.500  29.991  1.00 66.78  ? 495 VAL B CB  1 
ATOM 6506 C CG1 . VAL D 4 359 ? -92.446  41.452  30.703  1.00 72.27  ? 495 VAL B CG1 1 
ATOM 6507 C CG2 . VAL D 4 359 ? -90.888  41.170  28.771  1.00 59.61  ? 495 VAL B CG2 1 
ATOM 6508 N N   . ASN D 4 360 ? -91.472  38.417  32.432  1.00 67.90  ? 496 ASN B N   1 
ATOM 6509 C CA  . ASN D 4 360 ? -91.976  37.945  33.718  1.00 77.90  ? 496 ASN B CA  1 
ATOM 6510 C C   . ASN D 4 360 ? -90.858  37.856  34.751  1.00 80.00  ? 496 ASN B C   1 
ATOM 6511 O O   . ASN D 4 360 ? -91.060  38.186  35.926  1.00 72.38  ? 496 ASN B O   1 
ATOM 6512 C CB  . ASN D 4 360 ? -92.661  36.590  33.538  1.00 69.12  ? 496 ASN B CB  1 
ATOM 6513 C CG  . ASN D 4 360 ? -94.058  36.718  32.962  1.00 71.03  ? 496 ASN B CG  1 
ATOM 6514 O OD1 . ASN D 4 360 ? -94.415  37.752  32.397  1.00 73.52  ? 496 ASN B OD1 1 
ATOM 6515 N ND2 . ASN D 4 360 ? -94.849  35.657  33.081  1.00 65.12  ? 496 ASN B ND2 1 
ATOM 6516 N N   . GLU D 4 361 ? -89.672  37.411  34.331  1.00 81.12  ? 497 GLU B N   1 
ATOM 6517 C CA  . GLU D 4 361 ? -88.536  37.345  35.245  1.00 74.09  ? 497 GLU B CA  1 
ATOM 6518 C C   . GLU D 4 361 ? -88.146  38.728  35.749  1.00 73.66  ? 497 GLU B C   1 
ATOM 6519 O O   . GLU D 4 361 ? -87.877  38.909  36.942  1.00 89.46  ? 497 GLU B O   1 
ATOM 6520 C CB  . GLU D 4 361 ? -87.351  36.671  34.554  1.00 80.52  ? 497 GLU B CB  1 
ATOM 6521 C CG  . GLU D 4 361 ? -86.072  36.667  35.373  1.00 94.93  ? 497 GLU B CG  1 
ATOM 6522 C CD  . GLU D 4 361 ? -84.915  36.012  34.643  1.00 121.62 ? 497 GLU B CD  1 
ATOM 6523 O OE1 . GLU D 4 361 ? -84.946  35.961  33.393  1.00 109.31 ? 497 GLU B OE1 1 
ATOM 6524 O OE2 . GLU D 4 361 ? -83.975  35.546  35.322  1.00 134.33 ? 497 GLU B OE2 1 
ATOM 6525 N N   . LYS D 4 362 ? -88.111  39.720  34.856  1.00 67.61  ? 498 LYS B N   1 
ATOM 6526 C CA  . LYS D 4 362 ? -87.742  41.069  35.274  1.00 77.24  ? 498 LYS B CA  1 
ATOM 6527 C C   . LYS D 4 362 ? -88.777  41.654  36.228  1.00 82.71  ? 498 LYS B C   1 
ATOM 6528 O O   . LYS D 4 362 ? -88.422  42.344  37.192  1.00 82.29  ? 498 LYS B O   1 
ATOM 6529 C CB  . LYS D 4 362 ? -87.555  41.963  34.049  1.00 71.25  ? 498 LYS B CB  1 
ATOM 6530 C CG  . LYS D 4 362 ? -86.745  43.219  34.318  1.00 79.61  ? 498 LYS B CG  1 
ATOM 6531 C CD  . LYS D 4 362 ? -86.228  43.825  33.023  1.00 76.66  ? 498 LYS B CD  1 
ATOM 6532 C CE  . LYS D 4 362 ? -85.456  45.111  33.280  1.00 95.50  ? 498 LYS B CE  1 
ATOM 6533 N NZ  . LYS D 4 362 ? -83.985  44.890  33.348  1.00 95.26  ? 498 LYS B NZ  1 
ATOM 6534 N N   . ILE D 4 363 ? -90.062  41.392  35.976  1.00 74.88  ? 499 ILE B N   1 
ATOM 6535 C CA  . ILE D 4 363 ? -91.107  41.825  36.900  1.00 69.81  ? 499 ILE B CA  1 
ATOM 6536 C C   . ILE D 4 363 ? -90.937  41.138  38.248  1.00 84.19  ? 499 ILE B C   1 
ATOM 6537 O O   . ILE D 4 363 ? -91.090  41.761  39.307  1.00 83.60  ? 499 ILE B O   1 
ATOM 6538 C CB  . ILE D 4 363 ? -92.498  41.556  36.297  1.00 70.70  ? 499 ILE B CB  1 
ATOM 6539 C CG1 . ILE D 4 363 ? -92.718  42.429  35.060  1.00 74.51  ? 499 ILE B CG1 1 
ATOM 6540 C CG2 . ILE D 4 363 ? -93.587  41.801  37.333  1.00 67.66  ? 499 ILE B CG2 1 
ATOM 6541 C CD1 . ILE D 4 363 ? -94.123  42.360  34.500  1.00 64.55  ? 499 ILE B CD1 1 
ATOM 6542 N N   . ASN D 4 364 ? -90.615  39.842  38.229  1.00 84.83  ? 500 ASN B N   1 
ATOM 6543 C CA  . ASN D 4 364 ? -90.379  39.112  39.469  1.00 71.57  ? 500 ASN B CA  1 
ATOM 6544 C C   . ASN D 4 364 ? -89.209  39.707  40.244  1.00 80.36  ? 500 ASN B C   1 
ATOM 6545 O O   . ASN D 4 364 ? -89.282  39.864  41.468  1.00 87.36  ? 500 ASN B O   1 
ATOM 6546 C CB  . ASN D 4 364 ? -90.131  37.636  39.158  1.00 74.66  ? 500 ASN B CB  1 
ATOM 6547 C CG  . ASN D 4 364 ? -91.419  36.847  39.006  1.00 80.33  ? 500 ASN B CG  1 
ATOM 6548 O OD1 . ASN D 4 364 ? -92.511  37.416  39.009  1.00 85.71  ? 500 ASN B OD1 1 
ATOM 6549 N ND2 . ASN D 4 364 ? -91.296  35.533  38.846  1.00 69.36  ? 500 ASN B ND2 1 
ATOM 6550 N N   . GLN D 4 365 ? -88.125  40.056  39.546  1.00 82.74  ? 501 GLN B N   1 
ATOM 6551 C CA  . GLN D 4 365 ? -86.976  40.665  40.211  1.00 83.55  ? 501 GLN B CA  1 
ATOM 6552 C C   . GLN D 4 365 ? -87.344  42.007  40.834  1.00 81.01  ? 501 GLN B C   1 
ATOM 6553 O O   . GLN D 4 365 ? -86.917  42.317  41.951  1.00 90.84  ? 501 GLN B O   1 
ATOM 6554 C CB  . GLN D 4 365 ? -85.824  40.837  39.221  1.00 100.99 ? 501 GLN B CB  1 
ATOM 6555 C CG  . GLN D 4 365 ? -85.215  39.535  38.729  1.00 106.20 ? 501 GLN B CG  1 
ATOM 6556 C CD  . GLN D 4 365 ? -83.952  39.753  37.916  1.00 121.11 ? 501 GLN B CD  1 
ATOM 6557 O OE1 . GLN D 4 365 ? -83.336  40.818  37.977  1.00 135.40 ? 501 GLN B OE1 1 
ATOM 6558 N NE2 . GLN D 4 365 ? -83.564  38.745  37.142  1.00 112.85 ? 501 GLN B NE2 1 
ATOM 6559 N N   . SER D 4 366 ? -88.122  42.824  40.118  1.00 88.61  ? 502 SER B N   1 
ATOM 6560 C CA  . SER D 4 366 ? -88.524  44.124  40.651  1.00 91.22  ? 502 SER B CA  1 
ATOM 6561 C C   . SER D 4 366 ? -89.431  43.969  41.865  1.00 85.28  ? 502 SER B C   1 
ATOM 6562 O O   . SER D 4 366 ? -89.319  44.729  42.834  1.00 82.28  ? 502 SER B O   1 
ATOM 6563 C CB  . SER D 4 366 ? -89.219  44.947  39.566  1.00 81.62  ? 502 SER B CB  1 
ATOM 6564 O OG  . SER D 4 366 ? -88.353  45.187  38.473  1.00 78.63  ? 502 SER B OG  1 
ATOM 6565 N N   . LEU D 4 367 ? -90.355  43.006  41.820  1.00 84.72  ? 503 LEU B N   1 
ATOM 6566 C CA  . LEU D 4 367 ? -91.211  42.752  42.972  1.00 82.72  ? 503 LEU B CA  1 
ATOM 6567 C C   . LEU D 4 367 ? -90.427  42.137  44.125  1.00 89.88  ? 503 LEU B C   1 
ATOM 6568 O O   . LEU D 4 367 ? -90.722  42.418  45.293  1.00 86.82  ? 503 LEU B O   1 
ATOM 6569 C CB  . LEU D 4 367 ? -92.376  41.847  42.568  1.00 79.30  ? 503 LEU B CB  1 
ATOM 6570 C CG  . LEU D 4 367 ? -93.406  42.454  41.609  1.00 74.39  ? 503 LEU B CG  1 
ATOM 6571 C CD1 . LEU D 4 367 ? -94.611  41.538  41.459  1.00 68.55  ? 503 LEU B CD1 1 
ATOM 6572 C CD2 . LEU D 4 367 ? -93.838  43.843  42.064  1.00 51.70  ? 503 LEU B CD2 1 
ATOM 6573 N N   . ALA D 4 368 ? -89.432  41.299  43.820  1.00 94.63  ? 504 ALA B N   1 
ATOM 6574 C CA  . ALA D 4 368 ? -88.589  40.738  44.872  1.00 84.65  ? 504 ALA B CA  1 
ATOM 6575 C C   . ALA D 4 368 ? -87.809  41.831  45.591  1.00 93.74  ? 504 ALA B C   1 
ATOM 6576 O O   . ALA D 4 368 ? -87.657  41.790  46.817  1.00 100.66 ? 504 ALA B O   1 
ATOM 6577 C CB  . ALA D 4 368 ? -87.638  39.694  44.287  1.00 77.09  ? 504 ALA B CB  1 
ATOM 6578 N N   . PHE D 4 369 ? -87.305  42.816  44.843  1.00 85.32  ? 505 PHE B N   1 
ATOM 6579 C CA  . PHE D 4 369 ? -86.631  43.948  45.470  1.00 88.43  ? 505 PHE B CA  1 
ATOM 6580 C C   . PHE D 4 369 ? -87.585  44.714  46.377  1.00 92.11  ? 505 PHE B C   1 
ATOM 6581 O O   . PHE D 4 369 ? -87.201  45.152  47.468  1.00 103.53 ? 505 PHE B O   1 
ATOM 6582 C CB  . PHE D 4 369 ? -86.052  44.877  44.401  1.00 95.91  ? 505 PHE B CB  1 
ATOM 6583 C CG  . PHE D 4 369 ? -84.834  44.330  43.708  1.00 116.59 ? 505 PHE B CG  1 
ATOM 6584 C CD1 . PHE D 4 369 ? -84.193  43.196  44.181  1.00 114.50 ? 505 PHE B CD1 1 
ATOM 6585 C CD2 . PHE D 4 369 ? -84.332  44.952  42.574  1.00 107.81 ? 505 PHE B CD2 1 
ATOM 6586 C CE1 . PHE D 4 369 ? -83.075  42.695  43.539  1.00 114.25 ? 505 PHE B CE1 1 
ATOM 6587 C CE2 . PHE D 4 369 ? -83.215  44.456  41.929  1.00 103.29 ? 505 PHE B CE2 1 
ATOM 6588 C CZ  . PHE D 4 369 ? -82.586  43.326  42.412  1.00 107.53 ? 505 PHE B CZ  1 
ATOM 6589 N N   . ILE D 4 370 ? -88.833  44.891  45.937  1.00 90.61  ? 506 ILE B N   1 
ATOM 6590 C CA  . ILE D 4 370 ? -89.820  45.600  46.745  1.00 96.18  ? 506 ILE B CA  1 
ATOM 6591 C C   . ILE D 4 370 ? -90.127  44.822  48.020  1.00 100.39 ? 506 ILE B C   1 
ATOM 6592 O O   . ILE D 4 370 ? -90.178  45.391  49.117  1.00 105.81 ? 506 ILE B O   1 
ATOM 6593 C CB  . ILE D 4 370 ? -91.094  45.864  45.921  1.00 89.56  ? 506 ILE B CB  1 
ATOM 6594 C CG1 . ILE D 4 370 ? -90.804  46.863  44.798  1.00 103.01 ? 506 ILE B CG1 1 
ATOM 6595 C CG2 . ILE D 4 370 ? -92.212  46.378  46.813  1.00 91.14  ? 506 ILE B CG2 1 
ATOM 6596 C CD1 . ILE D 4 370 ? -91.999  47.164  43.917  1.00 96.73  ? 506 ILE B CD1 1 
ATOM 6597 N N   . ARG D 4 371 ? -90.339  43.509  47.895  1.00 104.70 ? 507 ARG B N   1 
ATOM 6598 C CA  . ARG D 4 371 ? -90.635  42.692  49.069  1.00 110.01 ? 507 ARG B CA  1 
ATOM 6599 C C   . ARG D 4 371 ? -89.447  42.637  50.024  1.00 112.02 ? 507 ARG B C   1 
ATOM 6600 O O   . ARG D 4 371 ? -89.624  42.705  51.247  1.00 105.79 ? 507 ARG B O   1 
ATOM 6601 C CB  . ARG D 4 371 ? -91.049  41.284  48.640  1.00 105.46 ? 507 ARG B CB  1 
ATOM 6602 C CG  . ARG D 4 371 ? -91.078  40.274  49.776  1.00 104.58 ? 507 ARG B CG  1 
ATOM 6603 C CD  . ARG D 4 371 ? -91.173  38.850  49.259  1.00 105.48 ? 507 ARG B CD  1 
ATOM 6604 N NE  . ARG D 4 371 ? -92.457  38.591  48.619  1.00 119.67 ? 507 ARG B NE  1 
ATOM 6605 C CZ  . ARG D 4 371 ? -92.927  37.382  48.347  1.00 139.40 ? 507 ARG B CZ  1 
ATOM 6606 N NH1 . ARG D 4 371 ? -92.243  36.290  48.648  1.00 136.84 ? 507 ARG B NH1 1 
ATOM 6607 N NH2 . ARG D 4 371 ? -94.115  37.264  47.761  1.00 156.15 ? 507 ARG B NH2 1 
ATOM 6608 N N   . LYS D 4 372 ? -88.230  42.514  49.486  1.00 106.70 ? 508 LYS B N   1 
ATOM 6609 C CA  . LYS D 4 372 ? -87.044  42.461  50.335  1.00 99.53  ? 508 LYS B CA  1 
ATOM 6610 C C   . LYS D 4 372 ? -86.888  43.743  51.145  1.00 100.54 ? 508 LYS B C   1 
ATOM 6611 O O   . LYS D 4 372 ? -86.574  43.698  52.340  1.00 106.45 ? 508 LYS B O   1 
ATOM 6612 C CB  . LYS D 4 372 ? -85.800  42.214  49.481  1.00 98.98  ? 508 LYS B CB  1 
ATOM 6613 C CG  . LYS D 4 372 ? -84.749  41.325  50.129  1.00 88.44  ? 508 LYS B CG  1 
ATOM 6614 C CD  . LYS D 4 372 ? -83.461  41.326  49.315  1.00 87.06  ? 508 LYS B CD  1 
ATOM 6615 C CE  . LYS D 4 372 ? -82.474  40.284  49.818  1.00 88.77  ? 508 LYS B CE  1 
ATOM 6616 N NZ  . LYS D 4 372 ? -82.785  38.927  49.286  1.00 76.43  ? 508 LYS B NZ  1 
ATOM 6617 N N   . SER D 4 373 ? -87.103  44.897  50.509  1.00 105.38 ? 509 SER B N   1 
ATOM 6618 C CA  . SER D 4 373 ? -87.016  46.165  51.226  1.00 99.59  ? 509 SER B CA  1 
ATOM 6619 C C   . SER D 4 373 ? -88.109  46.281  52.280  1.00 98.91  ? 509 SER B C   1 
ATOM 6620 O O   . SER D 4 373 ? -87.870  46.800  53.376  1.00 109.31 ? 509 SER B O   1 
ATOM 6621 C CB  . SER D 4 373 ? -87.093  47.332  50.243  1.00 91.06  ? 509 SER B CB  1 
ATOM 6622 O OG  . SER D 4 373 ? -87.189  48.566  50.931  1.00 104.22 ? 509 SER B OG  1 
ATOM 6623 N N   . ASP D 4 374 ? -89.320  45.815  51.961  1.00 107.19 ? 510 ASP B N   1 
ATOM 6624 C CA  . ASP D 4 374 ? -90.421  45.886  52.917  1.00 115.44 ? 510 ASP B CA  1 
ATOM 6625 C C   . ASP D 4 374 ? -90.196  44.953  54.101  1.00 117.80 ? 510 ASP B C   1 
ATOM 6626 O O   . ASP D 4 374 ? -90.537  45.296  55.240  1.00 109.54 ? 510 ASP B O   1 
ATOM 6627 C CB  . ASP D 4 374 ? -91.742  45.561  52.220  1.00 117.91 ? 510 ASP B CB  1 
ATOM 6628 C CG  . ASP D 4 374 ? -92.152  46.627  51.222  1.00 131.12 ? 510 ASP B CG  1 
ATOM 6629 O OD1 . ASP D 4 374 ? -91.783  47.805  51.420  1.00 122.74 ? 510 ASP B OD1 1 
ATOM 6630 O OD2 . ASP D 4 374 ? -92.841  46.288  50.237  1.00 139.77 ? 510 ASP B OD2 1 
ATOM 6631 N N   . GLU D 4 375 ? -89.647  43.761  53.852  1.00 117.35 ? 511 GLU B N   1 
ATOM 6632 C CA  . GLU D 4 375 ? -89.348  42.847  54.950  1.00 110.75 ? 511 GLU B CA  1 
ATOM 6633 C C   . GLU D 4 375 ? -88.295  43.432  55.883  1.00 113.43 ? 511 GLU B C   1 
ATOM 6634 O O   . GLU D 4 375 ? -88.430  43.353  57.110  1.00 109.78 ? 511 GLU B O   1 
ATOM 6635 C CB  . GLU D 4 375 ? -88.886  41.497  54.402  1.00 108.68 ? 511 GLU B CB  1 
ATOM 6636 C CG  . GLU D 4 375 ? -90.007  40.621  53.872  1.00 112.38 ? 511 GLU B CG  1 
ATOM 6637 C CD  . GLU D 4 375 ? -89.509  39.267  53.413  1.00 123.13 ? 511 GLU B CD  1 
ATOM 6638 O OE1 . GLU D 4 375 ? -88.305  38.988  53.589  1.00 121.66 ? 511 GLU B OE1 1 
ATOM 6639 O OE2 . GLU D 4 375 ? -90.319  38.482  52.876  1.00 128.90 ? 511 GLU B OE2 1 
ATOM 6640 N N   . LEU D 4 376 ? -87.239  44.023  55.319  1.00 103.42 ? 512 LEU B N   1 
ATOM 6641 C CA  . LEU D 4 376 ? -86.238  44.690  56.144  1.00 93.69  ? 512 LEU B CA  1 
ATOM 6642 C C   . LEU D 4 376 ? -86.856  45.850  56.910  1.00 93.89  ? 512 LEU B C   1 
ATOM 6643 O O   . LEU D 4 376 ? -86.581  46.037  58.100  1.00 108.30 ? 512 LEU B O   1 
ATOM 6644 C CB  . LEU D 4 376 ? -85.083  45.186  55.275  1.00 91.84  ? 512 LEU B CB  1 
ATOM 6645 C CG  . LEU D 4 376 ? -83.990  44.181  54.906  1.00 100.67 ? 512 LEU B CG  1 
ATOM 6646 C CD1 . LEU D 4 376 ? -82.910  44.845  54.059  1.00 96.48  ? 512 LEU B CD1 1 
ATOM 6647 C CD2 . LEU D 4 376 ? -83.393  43.550  56.151  1.00 94.47  ? 512 LEU B CD2 1 
ATOM 6648 N N   . LEU D 4 377 ? -87.704  46.632  56.242  1.00 98.85  ? 513 LEU B N   1 
ATOM 6649 C CA  . LEU D 4 377 ? -88.337  47.778  56.883  1.00 99.74  ? 513 LEU B CA  1 
ATOM 6650 C C   . LEU D 4 377 ? -89.266  47.339  58.009  1.00 101.07 ? 513 LEU B C   1 
ATOM 6651 O O   . LEU D 4 377 ? -89.362  48.011  59.043  1.00 105.63 ? 513 LEU B O   1 
ATOM 6652 C CB  . LEU D 4 377 ? -89.096  48.589  55.833  1.00 105.45 ? 513 LEU B CB  1 
ATOM 6653 C CG  . LEU D 4 377 ? -89.886  49.829  56.243  1.00 109.31 ? 513 LEU B CG  1 
ATOM 6654 C CD1 . LEU D 4 377 ? -88.968  50.882  56.846  1.00 93.16  ? 513 LEU B CD1 1 
ATOM 6655 C CD2 . LEU D 4 377 ? -90.628  50.375  55.033  1.00 125.96 ? 513 LEU B CD2 1 
ATOM 6656 N N   . SER D 4 378 ? -89.964  46.216  57.824  1.00 106.71 ? 514 SER B N   1 
ATOM 6657 C CA  . SER D 4 378 ? -90.878  45.732  58.855  1.00 120.10 ? 514 SER B CA  1 
ATOM 6658 C C   . SER D 4 378 ? -90.122  45.113  60.025  1.00 115.00 ? 514 SER B C   1 
ATOM 6659 O O   . SER D 4 378 ? -90.512  45.290  61.185  1.00 99.25  ? 514 SER B O   1 
ATOM 6660 C CB  . SER D 4 378 ? -91.856  44.723  58.256  1.00 127.35 ? 514 SER B CB  1 
ATOM 6661 O OG  . SER D 4 378 ? -91.174  43.575  57.778  1.00 122.17 ? 514 SER B OG  1 
ATOM 6662 N N   . ALA D 4 379 ? -89.046  44.374  59.740  1.00 109.82 ? 515 ALA B N   1 
ATOM 6663 C CA  . ALA D 4 379 ? -88.276  43.743  60.808  1.00 102.03 ? 515 ALA B CA  1 
ATOM 6664 C C   . ALA D 4 379 ? -87.579  44.773  61.688  1.00 108.76 ? 515 ALA B C   1 
ATOM 6665 O O   . ALA D 4 379 ? -87.406  44.543  62.890  1.00 102.28 ? 515 ALA B O   1 
ATOM 6666 C CB  . ALA D 4 379 ? -87.255  42.770  60.218  1.00 84.27  ? 515 ALA B CB  1 
ATOM 6667 N N   . ILE D 4 380 ? -87.180  45.909  61.110  1.00 110.17 ? 516 ILE B N   1 
ATOM 6668 C CA  . ILE D 4 380 ? -86.514  46.959  61.877  1.00 94.38  ? 516 ILE B CA  1 
ATOM 6669 C C   . ILE D 4 380 ? -87.456  47.529  62.931  1.00 97.73  ? 516 ILE B C   1 
ATOM 6670 O O   . ILE D 4 380 ? -87.030  47.890  64.035  1.00 105.16 ? 516 ILE B O   1 
ATOM 6671 C CB  . ILE D 4 380 ? -85.987  48.054  60.929  1.00 106.91 ? 516 ILE B CB  1 
ATOM 6672 C CG1 . ILE D 4 380 ? -84.763  47.554  60.166  1.00 102.30 ? 516 ILE B CG1 1 
ATOM 6673 C CG2 . ILE D 4 380 ? -85.647  49.320  61.686  1.00 117.32 ? 516 ILE B CG2 1 
ATOM 6674 C CD1 . ILE D 4 380 ? -84.352  48.458  59.029  1.00 106.19 ? 516 ILE B CD1 1 
ATOM 6675 N N   . GLY D 4 381 ? -88.750  47.609  62.614  1.00 109.49 ? 517 GLY B N   1 
ATOM 6676 C CA  . GLY D 4 381 ? -89.718  48.170  63.543  1.00 119.65 ? 517 GLY B CA  1 
ATOM 6677 C C   . GLY D 4 381 ? -89.876  47.386  64.830  1.00 106.44 ? 517 GLY B C   1 
ATOM 6678 O O   . GLY D 4 381 ? -90.451  47.902  65.793  1.00 116.46 ? 517 GLY B O   1 
ATOM 6679 N N   . GLY D 4 382 ? -89.384  46.152  64.870  1.00 112.92 ? 518 GLY B N   1 
ATOM 6680 C CA  . GLY D 4 382 ? -89.460  45.313  66.046  1.00 112.70 ? 518 GLY B CA  1 
ATOM 6681 C C   . GLY D 4 382 ? -88.348  45.504  67.054  1.00 101.72 ? 518 GLY B C   1 
ATOM 6682 O O   . GLY D 4 382 ? -88.271  44.745  68.026  1.00 94.64  ? 518 GLY B O   1 
ATOM 6683 N N   . TYR D 4 383 ? -87.480  46.490  66.855  1.00 102.02 ? 519 TYR B N   1 
ATOM 6684 C CA  . TYR D 4 383 ? -86.368  46.756  67.753  1.00 101.70 ? 519 TYR B CA  1 
ATOM 6685 C C   . TYR D 4 383 ? -86.666  47.972  68.626  1.00 98.51  ? 519 TYR B C   1 
ATOM 6686 O O   . TYR D 4 383 ? -87.673  48.663  68.456  1.00 102.95 ? 519 TYR B O   1 
ATOM 6687 C CB  . TYR D 4 383 ? -85.076  46.956  66.954  1.00 90.94  ? 519 TYR B CB  1 
ATOM 6688 C CG  . TYR D 4 383 ? -84.629  45.706  66.232  1.00 74.38  ? 519 TYR B CG  1 
ATOM 6689 C CD1 . TYR D 4 383 ? -83.931  44.708  66.897  1.00 85.53  ? 519 TYR B CD1 1 
ATOM 6690 C CD2 . TYR D 4 383 ? -84.925  45.514  64.891  1.00 104.33 ? 519 TYR B CD2 1 
ATOM 6691 C CE1 . TYR D 4 383 ? -83.527  43.560  66.244  1.00 91.06  ? 519 TYR B CE1 1 
ATOM 6692 C CE2 . TYR D 4 383 ? -84.529  44.369  64.229  1.00 106.62 ? 519 TYR B CE2 1 
ATOM 6693 C CZ  . TYR D 4 383 ? -83.830  43.395  64.909  1.00 108.11 ? 519 TYR B CZ  1 
ATOM 6694 O OH  . TYR D 4 383 ? -83.432  42.252  64.251  1.00 106.28 ? 519 TYR B OH  1 
ATOM 6695 N N   . ILE D 4 384 ? -85.772  48.225  69.577  1.00 80.54  ? 520 ILE B N   1 
ATOM 6696 C CA  . ILE D 4 384 ? -86.019  49.236  70.603  1.00 99.70  ? 520 ILE B CA  1 
ATOM 6697 C C   . ILE D 4 384 ? -85.094  50.434  70.418  1.00 100.25 ? 520 ILE B C   1 
ATOM 6698 O O   . ILE D 4 384 ? -83.924  50.268  70.044  1.00 97.98  ? 520 ILE B O   1 
ATOM 6699 C CB  . ILE D 4 384 ? -85.866  48.637  72.009  1.00 108.49 ? 520 ILE B CB  1 
ATOM 6700 C CG1 . ILE D 4 384 ? -84.570  47.833  72.112  1.00 103.40 ? 520 ILE B CG1 1 
ATOM 6701 C CG2 . ILE D 4 384 ? -87.053  47.753  72.336  1.00 107.89 ? 520 ILE B CG2 1 
ATOM 6702 C CD1 . ILE D 4 384 ? -84.432  47.078  73.413  1.00 92.29  ? 520 ILE B CD1 1 
ATOM 6703 N N   . PRO D 4 385 ? -85.574  51.657  70.680  1.00 97.15  ? 521 PRO B N   1 
ATOM 6704 C CA  . PRO D 4 385 ? -84.724  52.845  70.519  1.00 96.95  ? 521 PRO B CA  1 
ATOM 6705 C C   . PRO D 4 385 ? -83.715  53.013  71.645  1.00 102.04 ? 521 PRO B C   1 
ATOM 6706 O O   . PRO D 4 385 ? -83.591  52.151  72.520  1.00 109.30 ? 521 PRO B O   1 
ATOM 6707 C CB  . PRO D 4 385 ? -85.733  54.004  70.506  1.00 101.91 ? 521 PRO B CB  1 
ATOM 6708 C CG  . PRO D 4 385 ? -87.093  53.364  70.377  1.00 109.47 ? 521 PRO B CG  1 
ATOM 6709 C CD  . PRO D 4 385 ? -86.964  52.017  70.997  1.00 99.45  ? 521 PRO B CD  1 
ATOM 6710 N N   . GLU D 4 386 ? -82.988  54.128  71.623  1.00 97.76  ? 522 GLU B N   1 
ATOM 6711 C CA  . GLU D 4 386 ? -81.992  54.433  72.640  1.00 103.96 ? 522 GLU B CA  1 
ATOM 6712 C C   . GLU D 4 386 ? -82.645  55.154  73.813  1.00 115.66 ? 522 GLU B C   1 
ATOM 6713 O O   . GLU D 4 386 ? -83.445  56.075  73.618  1.00 115.02 ? 522 GLU B O   1 
ATOM 6714 C CB  . GLU D 4 386 ? -80.868  55.288  72.049  1.00 100.20 ? 522 GLU B CB  1 
ATOM 6715 C CG  . GLU D 4 386 ? -79.936  55.906  73.082  1.00 109.60 ? 522 GLU B CG  1 
ATOM 6716 C CD  . GLU D 4 386 ? -79.029  54.890  73.751  1.00 118.21 ? 522 GLU B CD  1 
ATOM 6717 O OE1 . GLU D 4 386 ? -78.283  54.190  73.035  1.00 121.81 ? 522 GLU B OE1 1 
ATOM 6718 O OE2 . GLU D 4 386 ? -79.067  54.786  74.995  1.00 121.97 ? 522 GLU B OE2 1 
ATOM 6719 N N   . ALA D 4 387 ? -82.306  54.726  75.027  1.00 116.47 ? 523 ALA B N   1 
ATOM 6720 C CA  . ALA D 4 387 ? -82.787  55.399  76.221  1.00 110.70 ? 523 ALA B CA  1 
ATOM 6721 C C   . ALA D 4 387 ? -82.169  56.794  76.318  1.00 116.10 ? 523 ALA B C   1 
ATOM 6722 O O   . ALA D 4 387 ? -81.074  57.030  75.801  1.00 120.25 ? 523 ALA B O   1 
ATOM 6723 C CB  . ALA D 4 387 ? -82.446  54.585  77.465  1.00 111.69 ? 523 ALA B CB  1 
ATOM 6724 N N   . PRO D 4 388 ? -82.855  57.738  76.965  1.00 116.25 ? 524 PRO B N   1 
ATOM 6725 C CA  . PRO D 4 388 ? -82.338  59.112  77.022  1.00 123.65 ? 524 PRO B CA  1 
ATOM 6726 C C   . PRO D 4 388 ? -80.945  59.171  77.633  1.00 126.97 ? 524 PRO B C   1 
ATOM 6727 O O   . PRO D 4 388 ? -80.641  58.482  78.609  1.00 126.52 ? 524 PRO B O   1 
ATOM 6728 C CB  . PRO D 4 388 ? -83.366  59.840  77.895  1.00 117.87 ? 524 PRO B CB  1 
ATOM 6729 C CG  . PRO D 4 388 ? -84.625  59.069  77.707  1.00 114.13 ? 524 PRO B CG  1 
ATOM 6730 C CD  . PRO D 4 388 ? -84.210  57.633  77.537  1.00 107.77 ? 524 PRO B CD  1 
ATOM 6731 N N   . ARG D 4 389 ? -80.093  60.005  77.036  1.00 134.96 ? 525 ARG B N   1 
ATOM 6732 C CA  . ARG D 4 389 ? -78.717  60.191  77.496  1.00 133.22 ? 525 ARG B CA  1 
ATOM 6733 C C   . ARG D 4 389 ? -78.705  61.380  78.449  1.00 138.95 ? 525 ARG B C   1 
ATOM 6734 O O   . ARG D 4 389 ? -78.536  62.531  78.043  1.00 131.88 ? 525 ARG B O   1 
ATOM 6735 C CB  . ARG D 4 389 ? -77.779  60.398  76.313  1.00 132.55 ? 525 ARG B CB  1 
ATOM 6736 C CG  . ARG D 4 389 ? -76.329  60.642  76.697  1.00 137.17 ? 525 ARG B CG  1 
ATOM 6737 C CD  . ARG D 4 389 ? -75.511  61.114  75.506  1.00 140.91 ? 525 ARG B CD  1 
ATOM 6738 N NE  . ARG D 4 389 ? -74.133  61.405  75.880  1.00 148.13 ? 525 ARG B NE  1 
ATOM 6739 C CZ  . ARG D 4 389 ? -73.107  60.597  75.651  1.00 148.20 ? 525 ARG B CZ  1 
ATOM 6740 N NH1 . ARG D 4 389 ? -73.262  59.444  75.020  1.00 137.72 ? 525 ARG B NH1 1 
ATOM 6741 N NH2 . ARG D 4 389 ? -71.895  60.956  76.063  1.00 153.00 ? 525 ARG B NH2 1 
ATOM 6742 N N   . ASP D 4 390 ? -78.891  61.094  79.743  1.00 147.94 ? 526 ASP B N   1 
ATOM 6743 C CA  . ASP D 4 390 ? -78.996  62.151  80.743  1.00 142.93 ? 526 ASP B CA  1 
ATOM 6744 C C   . ASP D 4 390 ? -78.231  61.832  82.026  1.00 138.72 ? 526 ASP B C   1 
ATOM 6745 O O   . ASP D 4 390 ? -78.456  62.491  83.049  1.00 141.79 ? 526 ASP B O   1 
ATOM 6746 C CB  . ASP D 4 390 ? -80.470  62.433  81.069  1.00 139.82 ? 526 ASP B CB  1 
ATOM 6747 C CG  . ASP D 4 390 ? -81.197  61.212  81.604  1.00 130.11 ? 526 ASP B CG  1 
ATOM 6748 O OD1 . ASP D 4 390 ? -80.599  60.115  81.622  1.00 125.18 ? 526 ASP B OD1 1 
ATOM 6749 O OD2 . ASP D 4 390 ? -82.374  61.348  82.001  1.00 127.94 ? 526 ASP B OD2 1 
ATOM 6750 N N   . GLY D 4 391 ? -77.338  60.845  82.005  1.00 132.64 ? 527 GLY B N   1 
ATOM 6751 C CA  . GLY D 4 391 ? -76.532  60.523  83.164  1.00 133.69 ? 527 GLY B CA  1 
ATOM 6752 C C   . GLY D 4 391 ? -77.182  59.617  84.187  1.00 136.24 ? 527 GLY B C   1 
ATOM 6753 O O   . GLY D 4 391 ? -76.555  59.328  85.215  1.00 135.89 ? 527 GLY B O   1 
ATOM 6754 N N   . GLN D 4 392 ? -78.408  59.157  83.949  1.00 136.88 ? 528 GLN B N   1 
ATOM 6755 C CA  . GLN D 4 392 ? -79.108  58.270  84.866  1.00 126.65 ? 528 GLN B CA  1 
ATOM 6756 C C   . GLN D 4 392 ? -79.544  57.008  84.135  1.00 117.84 ? 528 GLN B C   1 
ATOM 6757 O O   . GLN D 4 392 ? -79.912  57.058  82.957  1.00 129.45 ? 528 GLN B O   1 
ATOM 6758 C CB  . GLN D 4 392 ? -80.327  58.959  85.490  1.00 122.69 ? 528 GLN B CB  1 
ATOM 6759 C CG  . GLN D 4 392 ? -80.180  59.236  86.978  1.00 131.09 ? 528 GLN B CG  1 
ATOM 6760 C CD  . GLN D 4 392 ? -81.503  59.548  87.648  1.00 137.90 ? 528 GLN B CD  1 
ATOM 6761 O OE1 . GLN D 4 392 ? -82.510  59.786  86.981  1.00 140.21 ? 528 GLN B OE1 1 
ATOM 6762 N NE2 . GLN D 4 392 ? -81.507  59.548  88.977  1.00 118.81 ? 528 GLN B NE2 1 
ATOM 6763 N N   . ALA D 4 393 ? -79.504  55.881  84.840  1.00 110.61 ? 529 ALA B N   1 
ATOM 6764 C CA  . ALA D 4 393 ? -79.851  54.604  84.237  1.00 105.97 ? 529 ALA B CA  1 
ATOM 6765 C C   . ALA D 4 393 ? -81.349  54.516  83.961  1.00 106.89 ? 529 ALA B C   1 
ATOM 6766 O O   . ALA D 4 393 ? -82.172  55.123  84.652  1.00 100.43 ? 529 ALA B O   1 
ATOM 6767 C CB  . ALA D 4 393 ? -79.418  53.450  85.141  1.00 103.20 ? 529 ALA B CB  1 
ATOM 6768 N N   . TYR D 4 394 ? -81.695  53.741  82.933  1.00 101.79 ? 530 TYR B N   1 
ATOM 6769 C CA  . TYR D 4 394 ? -83.075  53.542  82.520  1.00 99.17  ? 530 TYR B CA  1 
ATOM 6770 C C   . TYR D 4 394 ? -83.357  52.055  82.370  1.00 87.57  ? 530 TYR B C   1 
ATOM 6771 O O   . TYR D 4 394 ? -82.462  51.262  82.066  1.00 70.36  ? 530 TYR B O   1 
ATOM 6772 C CB  . TYR D 4 394 ? -83.384  54.258  81.197  1.00 93.98  ? 530 TYR B CB  1 
ATOM 6773 C CG  . TYR D 4 394 ? -83.641  55.739  81.337  1.00 101.22 ? 530 TYR B CG  1 
ATOM 6774 C CD1 . TYR D 4 394 ? -82.591  56.646  81.358  1.00 107.30 ? 530 TYR B CD1 1 
ATOM 6775 C CD2 . TYR D 4 394 ? -84.936  56.231  81.440  1.00 105.29 ? 530 TYR B CD2 1 
ATOM 6776 C CE1 . TYR D 4 394 ? -82.821  58.002  81.483  1.00 116.44 ? 530 TYR B CE1 1 
ATOM 6777 C CE2 . TYR D 4 394 ? -85.176  57.587  81.564  1.00 120.89 ? 530 TYR B CE2 1 
ATOM 6778 C CZ  . TYR D 4 394 ? -84.114  58.468  81.585  1.00 126.45 ? 530 TYR B CZ  1 
ATOM 6779 O OH  . TYR D 4 394 ? -84.345  59.820  81.710  1.00 126.76 ? 530 TYR B OH  1 
ATOM 6780 N N   . VAL D 4 395 ? -84.620  51.688  82.581  1.00 94.23  ? 531 VAL B N   1 
ATOM 6781 C CA  . VAL D 4 395 ? -85.071  50.310  82.470  1.00 88.68  ? 531 VAL B CA  1 
ATOM 6782 C C   . VAL D 4 395 ? -86.281  50.278  81.544  1.00 92.28  ? 531 VAL B C   1 
ATOM 6783 O O   . VAL D 4 395 ? -86.967  51.282  81.341  1.00 95.89  ? 531 VAL B O   1 
ATOM 6784 C CB  . VAL D 4 395 ? -85.405  49.699  83.851  1.00 92.17  ? 531 VAL B CB  1 
ATOM 6785 C CG1 . VAL D 4 395 ? -86.789  50.130  84.314  1.00 89.79  ? 531 VAL B CG1 1 
ATOM 6786 C CG2 . VAL D 4 395 ? -85.277  48.186  83.822  1.00 96.87  ? 531 VAL B CG2 1 
ATOM 6787 N N   . ARG D 4 396 ? -86.528  49.106  80.964  1.00 85.45  ? 532 ARG B N   1 
ATOM 6788 C CA  . ARG D 4 396 ? -87.580  48.926  79.969  1.00 95.89  ? 532 ARG B CA  1 
ATOM 6789 C C   . ARG D 4 396 ? -88.809  48.337  80.653  1.00 94.31  ? 532 ARG B C   1 
ATOM 6790 O O   . ARG D 4 396 ? -88.823  47.150  80.998  1.00 93.80  ? 532 ARG B O   1 
ATOM 6791 C CB  . ARG D 4 396 ? -87.097  48.023  78.836  1.00 109.77 ? 532 ARG B CB  1 
ATOM 6792 C CG  . ARG D 4 396 ? -87.942  48.089  77.576  1.00 112.78 ? 532 ARG B CG  1 
ATOM 6793 C CD  . ARG D 4 396 ? -87.221  48.865  76.488  1.00 107.67 ? 532 ARG B CD  1 
ATOM 6794 N NE  . ARG D 4 396 ? -88.023  48.984  75.276  1.00 113.04 ? 532 ARG B NE  1 
ATOM 6795 C CZ  . ARG D 4 396 ? -88.391  50.135  74.733  1.00 107.99 ? 532 ARG B CZ  1 
ATOM 6796 N NH1 . ARG D 4 396 ? -88.047  51.295  75.268  1.00 109.52 ? 532 ARG B NH1 1 
ATOM 6797 N NH2 . ARG D 4 396 ? -89.128  50.123  73.626  1.00 107.97 ? 532 ARG B NH2 1 
ATOM 6798 N N   . LYS D 4 397 ? -89.843  49.160  80.840  1.00 102.26 ? 533 LYS B N   1 
ATOM 6799 C CA  . LYS D 4 397 ? -91.033  48.696  81.557  1.00 120.74 ? 533 LYS B CA  1 
ATOM 6800 C C   . LYS D 4 397 ? -91.987  47.924  80.646  1.00 133.46 ? 533 LYS B C   1 
ATOM 6801 O O   . LYS D 4 397 ? -92.190  46.719  80.822  1.00 139.33 ? 533 LYS B O   1 
ATOM 6802 C CB  . LYS D 4 397 ? -91.745  49.889  82.203  1.00 121.04 ? 533 LYS B CB  1 
ATOM 6803 C CG  . LYS D 4 397 ? -92.622  49.531  83.394  1.00 119.60 ? 533 LYS B CG  1 
ATOM 6804 C CD  . LYS D 4 397 ? -93.388  50.749  83.893  1.00 121.73 ? 533 LYS B CD  1 
ATOM 6805 C CE  . LYS D 4 397 ? -93.838  50.567  85.330  1.00 121.57 ? 533 LYS B CE  1 
ATOM 6806 N NZ  . LYS D 4 397 ? -94.674  49.349  85.495  1.00 127.66 ? 533 LYS B NZ  1 
ATOM 6807 N N   . ASP D 4 398 ? -92.588  48.606  79.667  1.00 136.90 ? 534 ASP B N   1 
ATOM 6808 C CA  . ASP D 4 398 ? -93.497  47.960  78.723  1.00 138.33 ? 534 ASP B CA  1 
ATOM 6809 C C   . ASP D 4 398 ? -93.016  48.087  77.285  1.00 128.57 ? 534 ASP B C   1 
ATOM 6810 O O   . ASP D 4 398 ? -92.708  47.076  76.645  1.00 122.71 ? 534 ASP B O   1 
ATOM 6811 C CB  . ASP D 4 398 ? -94.903  48.558  78.869  1.00 136.89 ? 534 ASP B CB  1 
ATOM 6812 C CG  . ASP D 4 398 ? -95.658  47.990  80.054  1.00 143.92 ? 534 ASP B CG  1 
ATOM 6813 O OD1 . ASP D 4 398 ? -95.266  48.282  81.205  1.00 141.46 ? 534 ASP B OD1 1 
ATOM 6814 O OD2 . ASP D 4 398 ? -96.639  47.244  79.833  1.00 156.07 ? 534 ASP B OD2 1 
ATOM 6815 N N   . GLY D 4 399 ? -92.914  49.311  76.777  1.00 124.15 ? 535 GLY B N   1 
ATOM 6816 C CA  . GLY D 4 399 ? -92.340  49.594  75.480  1.00 128.65 ? 535 GLY B CA  1 
ATOM 6817 C C   . GLY D 4 399 ? -91.569  50.896  75.529  1.00 126.94 ? 535 GLY B C   1 
ATOM 6818 O O   . GLY D 4 399 ? -91.095  51.390  74.502  1.00 123.11 ? 535 GLY B O   1 
ATOM 6819 N N   . GLU D 4 400 ? -91.421  51.449  76.732  1.00 134.22 ? 536 GLU B N   1 
ATOM 6820 C CA  . GLU D 4 400 ? -90.785  52.741  76.945  1.00 131.91 ? 536 GLU B CA  1 
ATOM 6821 C C   . GLU D 4 400 ? -89.735  52.617  78.043  1.00 110.45 ? 536 GLU B C   1 
ATOM 6822 O O   . GLU D 4 400 ? -89.658  51.608  78.749  1.00 103.45 ? 536 GLU B O   1 
ATOM 6823 C CB  . GLU D 4 400 ? -91.824  53.812  77.308  1.00 129.86 ? 536 GLU B CB  1 
ATOM 6824 C CG  . GLU D 4 400 ? -92.906  54.011  76.252  1.00 122.41 ? 536 GLU B CG  1 
ATOM 6825 C CD  . GLU D 4 400 ? -94.071  54.841  76.759  1.00 132.56 ? 536 GLU B CD  1 
ATOM 6826 O OE1 . GLU D 4 400 ? -94.856  54.320  77.578  1.00 130.11 ? 536 GLU B OE1 1 
ATOM 6827 O OE2 . GLU D 4 400 ? -94.205  56.010  76.340  1.00 137.94 ? 536 GLU B OE2 1 
ATOM 6828 N N   . TRP D 4 401 ? -88.923  53.660  78.189  1.00 108.51 ? 537 TRP B N   1 
ATOM 6829 C CA  . TRP D 4 401 ? -87.841  53.680  79.166  1.00 114.69 ? 537 TRP B CA  1 
ATOM 6830 C C   . TRP D 4 401 ? -88.284  54.427  80.419  1.00 119.76 ? 537 TRP B C   1 
ATOM 6831 O O   . TRP D 4 401 ? -88.720  55.581  80.340  1.00 130.99 ? 537 TRP B O   1 
ATOM 6832 C CB  . TRP D 4 401 ? -86.587  54.330  78.579  1.00 117.11 ? 537 TRP B CB  1 
ATOM 6833 C CG  . TRP D 4 401 ? -86.017  53.586  77.408  1.00 111.92 ? 537 TRP B CG  1 
ATOM 6834 C CD1 . TRP D 4 401 ? -86.156  53.906  76.090  1.00 117.14 ? 537 TRP B CD1 1 
ATOM 6835 C CD2 . TRP D 4 401 ? -85.213  52.399  77.450  1.00 112.09 ? 537 TRP B CD2 1 
ATOM 6836 N NE1 . TRP D 4 401 ? -85.494  52.991  75.308  1.00 116.52 ? 537 TRP B NE1 1 
ATOM 6837 C CE2 . TRP D 4 401 ? -84.905  52.057  76.119  1.00 106.81 ? 537 TRP B CE2 1 
ATOM 6838 C CE3 . TRP D 4 401 ? -84.724  51.594  78.483  1.00 107.08 ? 537 TRP B CE3 1 
ATOM 6839 C CZ2 . TRP D 4 401 ? -84.132  50.944  75.794  1.00 106.75 ? 537 TRP B CZ2 1 
ATOM 6840 C CZ3 . TRP D 4 401 ? -83.957  50.489  78.158  1.00 93.21  ? 537 TRP B CZ3 1 
ATOM 6841 C CH2 . TRP D 4 401 ? -83.669  50.174  76.825  1.00 104.89 ? 537 TRP B CH2 1 
ATOM 6842 N N   . VAL D 4 402 ? -88.173  53.765  81.569  1.00 112.37 ? 538 VAL B N   1 
ATOM 6843 C CA  . VAL D 4 402 ? -88.495  54.360  82.859  1.00 112.11 ? 538 VAL B CA  1 
ATOM 6844 C C   . VAL D 4 402 ? -87.248  54.315  83.730  1.00 109.13 ? 538 VAL B C   1 
ATOM 6845 O O   . VAL D 4 402 ? -86.416  53.409  83.610  1.00 99.10  ? 538 VAL B O   1 
ATOM 6846 C CB  . VAL D 4 402 ? -89.677  53.645  83.553  1.00 107.34 ? 538 VAL B CB  1 
ATOM 6847 C CG1 . VAL D 4 402 ? -90.226  54.494  84.693  1.00 109.12 ? 538 VAL B CG1 1 
ATOM 6848 C CG2 . VAL D 4 402 ? -90.773  53.332  82.548  1.00 105.11 ? 538 VAL B CG2 1 
ATOM 6849 N N   . LEU D 4 403 ? -87.118  55.310  84.606  1.00 115.67 ? 539 LEU B N   1 
ATOM 6850 C CA  . LEU D 4 403 ? -85.947  55.406  85.466  1.00 106.48 ? 539 LEU B CA  1 
ATOM 6851 C C   . LEU D 4 403 ? -85.834  54.187  86.373  1.00 107.68 ? 539 LEU B C   1 
ATOM 6852 O O   . LEU D 4 403 ? -86.831  53.690  86.905  1.00 109.72 ? 539 LEU B O   1 
ATOM 6853 C CB  . LEU D 4 403 ? -86.012  56.679  86.311  1.00 111.81 ? 539 LEU B CB  1 
ATOM 6854 C CG  . LEU D 4 403 ? -85.962  58.011  85.564  1.00 114.21 ? 539 LEU B CG  1 
ATOM 6855 C CD1 . LEU D 4 403 ? -86.380  59.154  86.476  1.00 105.20 ? 539 LEU B CD1 1 
ATOM 6856 C CD2 . LEU D 4 403 ? -84.567  58.243  85.016  1.00 108.57 ? 539 LEU B CD2 1 
ATOM 6857 N N   . LEU D 4 404 ? -84.601  53.702  86.541  1.00 103.37 ? 540 LEU B N   1 
ATOM 6858 C CA  . LEU D 4 404 ? -84.357  52.607  87.474  1.00 100.85 ? 540 LEU B CA  1 
ATOM 6859 C C   . LEU D 4 404 ? -84.679  53.015  88.906  1.00 112.12 ? 540 LEU B C   1 
ATOM 6860 O O   . LEU D 4 404 ? -85.049  52.166  89.725  1.00 119.33 ? 540 LEU B O   1 
ATOM 6861 C CB  . LEU D 4 404 ? -82.905  52.138  87.358  1.00 87.82  ? 540 LEU B CB  1 
ATOM 6862 C CG  . LEU D 4 404 ? -82.399  51.059  88.322  1.00 88.08  ? 540 LEU B CG  1 
ATOM 6863 C CD1 . LEU D 4 404 ? -83.272  49.808  88.291  1.00 68.21  ? 540 LEU B CD1 1 
ATOM 6864 C CD2 . LEU D 4 404 ? -80.948  50.712  88.017  1.00 68.27  ? 540 LEU B CD2 1 
ATOM 6865 N N   . SER D 4 405 ? -84.559  54.309  89.220  1.00 123.91 ? 541 SER B N   1 
ATOM 6866 C CA  . SER D 4 405 ? -84.805  54.781  90.580  1.00 116.93 ? 541 SER B CA  1 
ATOM 6867 C C   . SER D 4 405 ? -86.249  54.553  91.013  1.00 108.71 ? 541 SER B C   1 
ATOM 6868 O O   . SER D 4 405 ? -86.521  54.423  92.211  1.00 116.20 ? 541 SER B O   1 
ATOM 6869 C CB  . SER D 4 405 ? -84.447  56.263  90.689  1.00 121.50 ? 541 SER B CB  1 
ATOM 6870 O OG  . SER D 4 405 ? -85.143  57.030  89.721  1.00 112.20 ? 541 SER B OG  1 
ATOM 6871 N N   . THR D 4 406 ? -87.184  54.508  90.061  1.00 107.98 ? 542 THR B N   1 
ATOM 6872 C CA  . THR D 4 406 ? -88.584  54.280  90.408  1.00 110.50 ? 542 THR B CA  1 
ATOM 6873 C C   . THR D 4 406 ? -88.788  52.912  91.046  1.00 106.65 ? 542 THR B C   1 
ATOM 6874 O O   . THR D 4 406 ? -89.675  52.745  91.891  1.00 114.11 ? 542 THR B O   1 
ATOM 6875 C CB  . THR D 4 406 ? -89.462  54.420  89.162  1.00 105.74 ? 542 THR B CB  1 
ATOM 6876 O OG1 . THR D 4 406 ? -89.098  55.610  88.451  1.00 117.36 ? 542 THR B OG1 1 
ATOM 6877 C CG2 . THR D 4 406 ? -90.932  54.502  89.545  1.00 89.53  ? 542 THR B CG2 1 
ATOM 6878 N N   . PHE D 4 407 ? -87.973  51.929  90.670  1.00 103.56 ? 543 PHE B N   1 
ATOM 6879 C CA  . PHE D 4 407 ? -88.118  50.559  91.139  1.00 109.88 ? 543 PHE B CA  1 
ATOM 6880 C C   . PHE D 4 407 ? -87.145  50.207  92.259  1.00 115.51 ? 543 PHE B C   1 
ATOM 6881 O O   . PHE D 4 407 ? -87.025  49.030  92.615  1.00 111.33 ? 543 PHE B O   1 
ATOM 6882 C CB  . PHE D 4 407 ? -87.953  49.591  89.966  1.00 106.69 ? 543 PHE B CB  1 
ATOM 6883 C CG  . PHE D 4 407 ? -88.830  49.918  88.790  1.00 109.66 ? 543 PHE B CG  1 
ATOM 6884 C CD1 . PHE D 4 407 ? -90.126  49.434  88.723  1.00 112.95 ? 543 PHE B CD1 1 
ATOM 6885 C CD2 . PHE D 4 407 ? -88.366  50.723  87.763  1.00 109.05 ? 543 PHE B CD2 1 
ATOM 6886 C CE1 . PHE D 4 407 ? -90.940  49.737  87.647  1.00 111.52 ? 543 PHE B CE1 1 
ATOM 6887 C CE2 . PHE D 4 407 ? -89.177  51.032  86.687  1.00 108.62 ? 543 PHE B CE2 1 
ATOM 6888 C CZ  . PHE D 4 407 ? -90.464  50.537  86.628  1.00 113.74 ? 543 PHE B CZ  1 
ATOM 6889 N N   . LEU D 4 408 ? -86.453  51.193  92.822  1.00 114.78 ? 544 LEU B N   1 
ATOM 6890 C CA  . LEU D 4 408 ? -85.544  50.949  93.937  1.00 120.08 ? 544 LEU B CA  1 
ATOM 6891 C C   . LEU D 4 408 ? -86.032  51.632  95.214  1.00 113.75 ? 544 LEU B C   1 
ATOM 6892 O O   . LEU D 4 408 ? -87.180  52.068  95.303  1.00 101.41 ? 544 LEU B O   1 
ATOM 6893 C CB  . LEU D 4 408 ? -84.130  51.425  93.592  1.00 113.77 ? 544 LEU B CB  1 
ATOM 6894 C CG  . LEU D 4 408 ? -83.484  50.803  92.350  1.00 100.91 ? 544 LEU B CG  1 
ATOM 6895 C CD1 . LEU D 4 408 ? -82.019  51.200  92.242  1.00 81.71  ? 544 LEU B CD1 1 
ATOM 6896 C CD2 . LEU D 4 408 ? -83.627  49.288  92.374  1.00 83.39  ? 544 LEU B CD2 1 
# 
