data_8UL1
# 
_entry.id   8UL1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UL1         pdb_00008ul1 10.2210/pdb8ul1/pdb 
WWPDB D_1000278257 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_database_PDB_caveat.id 
_database_PDB_caveat.text 
1 
;Residues PHE 1 61 and PIA 1 64 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.03 A.
;
2 
;Residues PIA 1 64 and ASN 1 65 that are next to each other in the sample sequence are not properly linked: distance between C and N is 0.99 A.
;
3 
;Residues PIA 2 64 and ASN 2 65 that are next to each other in the sample sequence are not properly linked: distance between C and N is 1.67 A.
;
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UL1 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              j.vanthor@imperial.ac.uk 
_pdbx_contact_author.name_first         Jasper 
_pdbx_contact_author.name_last          'van Thor' 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6356-3116 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Baxter, J.M.'   1 0000-0002-4641-6760 
'van Thor, J.J.' 2 0000-0001-6356-3116 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Am.Chem.Soc. 
_citation.journal_id_ASTM           JACSAT 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           1520-5126 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            146 
_citation.language                  ? 
_citation.page_first                16394 
_citation.page_last                 16403 
_citation.title                     
;Power Density Titration of Reversible Photoisomerization of a Fluorescent Protein Chromophore in the Presence of Thermally Driven Barrier Crossing Shown by Quantitative Millisecond Serial Synchrotron X-ray Crystallography.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/jacs.3c12883 
_citation.pdbx_database_id_PubMed   38848551 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Baxter, J.M.'             1  ?                   
primary 'Hutchison, C.D.M.'        2  ?                   
primary 'Fadini, A.'               3  ?                   
primary 'Maghlaoui, K.'            4  ?                   
primary 'Cordon-Preciado, V.'      5  ?                   
primary 'Morgan, R.M.L.'           6  ?                   
primary 'Agthe, M.'                7  ?                   
primary 'Horrell, S.'              8  ?                   
primary 'Tellkamp, F.'             9  ?                   
primary 'Mehrabi, P.'              10 0000-0003-3211-6959 
primary 'Pfeifer, Y.'              11 ?                   
primary 'Muller-Werkmeister, H.M.' 12 0000-0001-9471-882X 
primary 'von Stetten, D.'          13 0000-0001-7906-9788 
primary 'Pearson, A.R.'            14 ?                   
primary 'van Thor, J.J.'           15 0000-0001-6356-3116 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'rsKiiro trans structure' 25152.490 2   ? ? ? ? 
2 non-polymer syn 'SULFATE ION'             96.063    4   ? ? ? ? 
3 non-polymer syn GLYCEROL                  92.094    1   ? ? ? ? 
4 water       nat water                     18.015    346 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   yes 
_entity_poly.pdbx_seq_one_letter_code       
;MSAIKPDMKIKLRMEGNVNGHHFVIDGDGTGKPFEGKQSMDLEVKEGGPLPFAFDILTTAF(PIA)NRVFAKYPDNIQDY
FKQSFPKGYSWERSLTFEDGGICNARNDITMEGDTFYNKVRFYGTNFPANGPVMQKKTLKWEPSTEKMYVRDGVLTGDVE
TALLLEGNAHYRCDFRTTYKAKEKGVKLPGAHFVDHCIEILSHDKDYNKVKLYEHAVAHSGLPN
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSAIKPDMKIKLRMEGNVNGHHFVIDGDGTGKPFEGKQSMDLEVKEGGPLPFAFDILTTAFAYGNRVFAKYPDNIQDYFK
QSFPKGYSWERSLTFEDGGICNARNDITMEGDTFYNKVRFYGTNFPANGPVMQKKTLKWEPSTEKMYVRDGVLTGDVETA
LLLEGNAHYRCDFRTTYKAKEKGVKLPGAHFVDHCIEILSHDKDYNKVKLYEHAVAHSGLPN
;
_entity_poly.pdbx_strand_id                 1,2 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION' SO4 
3 GLYCEROL      GOL 
4 water         HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   ALA n 
1 4   ILE n 
1 5   LYS n 
1 6   PRO n 
1 7   ASP n 
1 8   MET n 
1 9   LYS n 
1 10  ILE n 
1 11  LYS n 
1 12  LEU n 
1 13  ARG n 
1 14  MET n 
1 15  GLU n 
1 16  GLY n 
1 17  ASN n 
1 18  VAL n 
1 19  ASN n 
1 20  GLY n 
1 21  HIS n 
1 22  HIS n 
1 23  PHE n 
1 24  VAL n 
1 25  ILE n 
1 26  ASP n 
1 27  GLY n 
1 28  ASP n 
1 29  GLY n 
1 30  THR n 
1 31  GLY n 
1 32  LYS n 
1 33  PRO n 
1 34  PHE n 
1 35  GLU n 
1 36  GLY n 
1 37  LYS n 
1 38  GLN n 
1 39  SER n 
1 40  MET n 
1 41  ASP n 
1 42  LEU n 
1 43  GLU n 
1 44  VAL n 
1 45  LYS n 
1 46  GLU n 
1 47  GLY n 
1 48  GLY n 
1 49  PRO n 
1 50  LEU n 
1 51  PRO n 
1 52  PHE n 
1 53  ALA n 
1 54  PHE n 
1 55  ASP n 
1 56  ILE n 
1 57  LEU n 
1 58  THR n 
1 59  THR n 
1 60  ALA n 
1 61  PHE n 
1 62  PIA n 
1 63  ASN n 
1 64  ARG n 
1 65  VAL n 
1 66  PHE n 
1 67  ALA n 
1 68  LYS n 
1 69  TYR n 
1 70  PRO n 
1 71  ASP n 
1 72  ASN n 
1 73  ILE n 
1 74  GLN n 
1 75  ASP n 
1 76  TYR n 
1 77  PHE n 
1 78  LYS n 
1 79  GLN n 
1 80  SER n 
1 81  PHE n 
1 82  PRO n 
1 83  LYS n 
1 84  GLY n 
1 85  TYR n 
1 86  SER n 
1 87  TRP n 
1 88  GLU n 
1 89  ARG n 
1 90  SER n 
1 91  LEU n 
1 92  THR n 
1 93  PHE n 
1 94  GLU n 
1 95  ASP n 
1 96  GLY n 
1 97  GLY n 
1 98  ILE n 
1 99  CYS n 
1 100 ASN n 
1 101 ALA n 
1 102 ARG n 
1 103 ASN n 
1 104 ASP n 
1 105 ILE n 
1 106 THR n 
1 107 MET n 
1 108 GLU n 
1 109 GLY n 
1 110 ASP n 
1 111 THR n 
1 112 PHE n 
1 113 TYR n 
1 114 ASN n 
1 115 LYS n 
1 116 VAL n 
1 117 ARG n 
1 118 PHE n 
1 119 TYR n 
1 120 GLY n 
1 121 THR n 
1 122 ASN n 
1 123 PHE n 
1 124 PRO n 
1 125 ALA n 
1 126 ASN n 
1 127 GLY n 
1 128 PRO n 
1 129 VAL n 
1 130 MET n 
1 131 GLN n 
1 132 LYS n 
1 133 LYS n 
1 134 THR n 
1 135 LEU n 
1 136 LYS n 
1 137 TRP n 
1 138 GLU n 
1 139 PRO n 
1 140 SER n 
1 141 THR n 
1 142 GLU n 
1 143 LYS n 
1 144 MET n 
1 145 TYR n 
1 146 VAL n 
1 147 ARG n 
1 148 ASP n 
1 149 GLY n 
1 150 VAL n 
1 151 LEU n 
1 152 THR n 
1 153 GLY n 
1 154 ASP n 
1 155 VAL n 
1 156 GLU n 
1 157 THR n 
1 158 ALA n 
1 159 LEU n 
1 160 LEU n 
1 161 LEU n 
1 162 GLU n 
1 163 GLY n 
1 164 ASN n 
1 165 ALA n 
1 166 HIS n 
1 167 TYR n 
1 168 ARG n 
1 169 CYS n 
1 170 ASP n 
1 171 PHE n 
1 172 ARG n 
1 173 THR n 
1 174 THR n 
1 175 TYR n 
1 176 LYS n 
1 177 ALA n 
1 178 LYS n 
1 179 GLU n 
1 180 LYS n 
1 181 GLY n 
1 182 VAL n 
1 183 LYS n 
1 184 LEU n 
1 185 PRO n 
1 186 GLY n 
1 187 ALA n 
1 188 HIS n 
1 189 PHE n 
1 190 VAL n 
1 191 ASP n 
1 192 HIS n 
1 193 CYS n 
1 194 ILE n 
1 195 GLU n 
1 196 ILE n 
1 197 LEU n 
1 198 SER n 
1 199 HIS n 
1 200 ASP n 
1 201 LYS n 
1 202 ASP n 
1 203 TYR n 
1 204 ASN n 
1 205 LYS n 
1 206 VAL n 
1 207 LYS n 
1 208 LEU n 
1 209 TYR n 
1 210 GLU n 
1 211 HIS n 
1 212 ALA n 
1 213 VAL n 
1 214 ALA n 
1 215 HIS n 
1 216 SER n 
1 217 GLY n 
1 218 LEU n 
1 219 PRO n 
1 220 ASN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   220 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Lobophyllia hemprichii' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     46758 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                               ? 
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                              ? 
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                            ? 
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                       ? 
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                              ? 
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                             ? 
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                       ? 
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                               ? 
'C2 H5 N O2'     75.067  
GOL non-polymer         . GLYCEROL                                                                                              
'GLYCERIN; PROPANE-1,2,3-TRIOL' 'C3 H8 O3'       92.094  
HIS 'L-peptide linking' y HISTIDINE                                                                                             ? 
'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                                                                                 ? 
'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                                                                            ? 
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                               ? 
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                                ? 
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                            ? 
'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                                                                         ? 
'C9 H11 N O2'    165.189 
PIA 'L-peptide linking' n '[(4Z)-2-[(1S)-1-aminoethyl]-4-(4-hydroxybenzylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]acetic acid' ? 
'C14 H15 N3 O4'  289.287 
PRO 'L-peptide linking' y PROLINE                                                                                               ? 
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                                ? 
'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'                                                                                         ? 
'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE                                                                                             ? 
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                            ? 
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                              ? 
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                                ? 
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   1 . n 
A 1 2   SER 2   2   2   SER SER 1 . n 
A 1 3   ALA 3   3   3   ALA ALA 1 . n 
A 1 4   ILE 4   4   4   ILE ILE 1 . n 
A 1 5   LYS 5   5   5   LYS LYS 1 . n 
A 1 6   PRO 6   6   6   PRO PRO 1 . n 
A 1 7   ASP 7   7   7   ASP ASP 1 . n 
A 1 8   MET 8   8   8   MET MET 1 . n 
A 1 9   LYS 9   9   9   LYS LYS 1 . n 
A 1 10  ILE 10  10  10  ILE ILE 1 . n 
A 1 11  LYS 11  11  11  LYS LYS 1 . n 
A 1 12  LEU 12  12  12  LEU LEU 1 . n 
A 1 13  ARG 13  13  13  ARG ARG 1 . n 
A 1 14  MET 14  14  14  MET MET 1 . n 
A 1 15  GLU 15  15  15  GLU GLU 1 . n 
A 1 16  GLY 16  16  16  GLY GLY 1 . n 
A 1 17  ASN 17  17  17  ASN ASN 1 . n 
A 1 18  VAL 18  18  18  VAL VAL 1 . n 
A 1 19  ASN 19  19  19  ASN ASN 1 . n 
A 1 20  GLY 20  20  20  GLY GLY 1 . n 
A 1 21  HIS 21  21  21  HIS HIS 1 . n 
A 1 22  HIS 22  22  22  HIS HIS 1 . n 
A 1 23  PHE 23  23  23  PHE PHE 1 . n 
A 1 24  VAL 24  24  24  VAL VAL 1 . n 
A 1 25  ILE 25  25  25  ILE ILE 1 . n 
A 1 26  ASP 26  26  26  ASP ASP 1 . n 
A 1 27  GLY 27  27  27  GLY GLY 1 . n 
A 1 28  ASP 28  28  28  ASP ASP 1 . n 
A 1 29  GLY 29  29  29  GLY GLY 1 . n 
A 1 30  THR 30  30  30  THR THR 1 . n 
A 1 31  GLY 31  31  31  GLY GLY 1 . n 
A 1 32  LYS 32  32  32  LYS LYS 1 . n 
A 1 33  PRO 33  33  33  PRO PRO 1 . n 
A 1 34  PHE 34  34  34  PHE PHE 1 . n 
A 1 35  GLU 35  35  35  GLU GLU 1 . n 
A 1 36  GLY 36  36  36  GLY GLY 1 . n 
A 1 37  LYS 37  37  37  LYS LYS 1 . n 
A 1 38  GLN 38  38  38  GLN GLN 1 . n 
A 1 39  SER 39  39  39  SER SER 1 . n 
A 1 40  MET 40  40  40  MET MET 1 . n 
A 1 41  ASP 41  41  41  ASP ASP 1 . n 
A 1 42  LEU 42  42  42  LEU LEU 1 . n 
A 1 43  GLU 43  43  43  GLU GLU 1 . n 
A 1 44  VAL 44  44  44  VAL VAL 1 . n 
A 1 45  LYS 45  45  45  LYS LYS 1 . n 
A 1 46  GLU 46  46  46  GLU GLU 1 . n 
A 1 47  GLY 47  47  47  GLY GLY 1 . n 
A 1 48  GLY 48  48  48  GLY GLY 1 . n 
A 1 49  PRO 49  49  49  PRO PRO 1 . n 
A 1 50  LEU 50  50  50  LEU LEU 1 . n 
A 1 51  PRO 51  51  51  PRO PRO 1 . n 
A 1 52  PHE 52  52  52  PHE PHE 1 . n 
A 1 53  ALA 53  53  53  ALA ALA 1 . n 
A 1 54  PHE 54  54  54  PHE PHE 1 . n 
A 1 55  ASP 55  55  55  ASP ASP 1 . n 
A 1 56  ILE 56  56  56  ILE ILE 1 . n 
A 1 57  LEU 57  57  57  LEU LEU 1 . n 
A 1 58  THR 58  58  58  THR THR 1 . n 
A 1 59  THR 59  59  59  THR THR 1 . n 
A 1 60  ALA 60  60  60  ALA ALA 1 . n 
A 1 61  PHE 61  61  61  PHE PHE 1 . n 
A 1 62  PIA 62  64  64  PIA PIA 1 . n 
A 1 63  ASN 63  65  65  ASN ASN 1 . n 
A 1 64  ARG 64  66  66  ARG ARG 1 . n 
A 1 65  VAL 65  67  67  VAL VAL 1 . n 
A 1 66  PHE 66  68  68  PHE PHE 1 . n 
A 1 67  ALA 67  69  69  ALA ALA 1 . n 
A 1 68  LYS 68  70  70  LYS LYS 1 . n 
A 1 69  TYR 69  71  71  TYR TYR 1 . n 
A 1 70  PRO 70  72  72  PRO PRO 1 . n 
A 1 71  ASP 71  73  73  ASP ASP 1 . n 
A 1 72  ASN 72  74  74  ASN ASN 1 . n 
A 1 73  ILE 73  75  75  ILE ILE 1 . n 
A 1 74  GLN 74  76  76  GLN GLN 1 . n 
A 1 75  ASP 75  77  77  ASP ASP 1 . n 
A 1 76  TYR 76  78  78  TYR TYR 1 . n 
A 1 77  PHE 77  79  79  PHE PHE 1 . n 
A 1 78  LYS 78  80  80  LYS LYS 1 . n 
A 1 79  GLN 79  81  81  GLN GLN 1 . n 
A 1 80  SER 80  82  82  SER SER 1 . n 
A 1 81  PHE 81  83  83  PHE PHE 1 . n 
A 1 82  PRO 82  84  84  PRO PRO 1 . n 
A 1 83  LYS 83  85  85  LYS LYS 1 . n 
A 1 84  GLY 84  86  86  GLY GLY 1 . n 
A 1 85  TYR 85  87  87  TYR TYR 1 . n 
A 1 86  SER 86  88  88  SER SER 1 . n 
A 1 87  TRP 87  89  89  TRP TRP 1 . n 
A 1 88  GLU 88  90  90  GLU GLU 1 . n 
A 1 89  ARG 89  91  91  ARG ARG 1 . n 
A 1 90  SER 90  92  92  SER SER 1 . n 
A 1 91  LEU 91  93  93  LEU LEU 1 . n 
A 1 92  THR 92  94  94  THR THR 1 . n 
A 1 93  PHE 93  95  95  PHE PHE 1 . n 
A 1 94  GLU 94  96  96  GLU GLU 1 . n 
A 1 95  ASP 95  97  97  ASP ASP 1 . n 
A 1 96  GLY 96  98  98  GLY GLY 1 . n 
A 1 97  GLY 97  99  99  GLY GLY 1 . n 
A 1 98  ILE 98  100 100 ILE ILE 1 . n 
A 1 99  CYS 99  101 101 CYS CYS 1 . n 
A 1 100 ASN 100 102 102 ASN ASN 1 . n 
A 1 101 ALA 101 103 103 ALA ALA 1 . n 
A 1 102 ARG 102 104 104 ARG ARG 1 . n 
A 1 103 ASN 103 105 105 ASN ASN 1 . n 
A 1 104 ASP 104 106 106 ASP ASP 1 . n 
A 1 105 ILE 105 107 107 ILE ILE 1 . n 
A 1 106 THR 106 108 108 THR THR 1 . n 
A 1 107 MET 107 109 109 MET MET 1 . n 
A 1 108 GLU 108 110 110 GLU GLU 1 . n 
A 1 109 GLY 109 111 111 GLY GLY 1 . n 
A 1 110 ASP 110 112 112 ASP ASP 1 . n 
A 1 111 THR 111 113 113 THR THR 1 . n 
A 1 112 PHE 112 114 114 PHE PHE 1 . n 
A 1 113 TYR 113 115 115 TYR TYR 1 . n 
A 1 114 ASN 114 116 116 ASN ASN 1 . n 
A 1 115 LYS 115 117 117 LYS LYS 1 . n 
A 1 116 VAL 116 118 118 VAL VAL 1 . n 
A 1 117 ARG 117 119 119 ARG ARG 1 . n 
A 1 118 PHE 118 120 120 PHE PHE 1 . n 
A 1 119 TYR 119 121 121 TYR TYR 1 . n 
A 1 120 GLY 120 122 122 GLY GLY 1 . n 
A 1 121 THR 121 123 123 THR THR 1 . n 
A 1 122 ASN 122 124 124 ASN ASN 1 . n 
A 1 123 PHE 123 125 125 PHE PHE 1 . n 
A 1 124 PRO 124 126 126 PRO PRO 1 . n 
A 1 125 ALA 125 127 127 ALA ALA 1 . n 
A 1 126 ASN 126 128 128 ASN ASN 1 . n 
A 1 127 GLY 127 129 129 GLY GLY 1 . n 
A 1 128 PRO 128 130 130 PRO PRO 1 . n 
A 1 129 VAL 129 131 131 VAL VAL 1 . n 
A 1 130 MET 130 132 132 MET MET 1 . n 
A 1 131 GLN 131 133 133 GLN GLN 1 . n 
A 1 132 LYS 132 134 134 LYS LYS 1 . n 
A 1 133 LYS 133 135 135 LYS LYS 1 . n 
A 1 134 THR 134 136 136 THR THR 1 . n 
A 1 135 LEU 135 137 137 LEU LEU 1 . n 
A 1 136 LYS 136 138 138 LYS LYS 1 . n 
A 1 137 TRP 137 139 139 TRP TRP 1 . n 
A 1 138 GLU 138 140 140 GLU GLU 1 . n 
A 1 139 PRO 139 141 141 PRO PRO 1 . n 
A 1 140 SER 140 142 142 SER SER 1 . n 
A 1 141 THR 141 143 143 THR THR 1 . n 
A 1 142 GLU 142 144 144 GLU GLU 1 . n 
A 1 143 LYS 143 145 145 LYS LYS 1 . n 
A 1 144 MET 144 146 146 MET MET 1 . n 
A 1 145 TYR 145 147 147 TYR TYR 1 . n 
A 1 146 VAL 146 148 148 VAL VAL 1 . n 
A 1 147 ARG 147 149 149 ARG ARG 1 . n 
A 1 148 ASP 148 150 150 ASP ASP 1 . n 
A 1 149 GLY 149 151 151 GLY GLY 1 . n 
A 1 150 VAL 150 152 152 VAL VAL 1 . n 
A 1 151 LEU 151 153 153 LEU LEU 1 . n 
A 1 152 THR 152 154 154 THR THR 1 . n 
A 1 153 GLY 153 155 155 GLY GLY 1 . n 
A 1 154 ASP 154 156 156 ASP ASP 1 . n 
A 1 155 VAL 155 157 157 VAL VAL 1 . n 
A 1 156 GLU 156 158 158 GLU GLU 1 . n 
A 1 157 THR 157 159 159 THR THR 1 . n 
A 1 158 ALA 158 160 160 ALA ALA 1 . n 
A 1 159 LEU 159 161 161 LEU LEU 1 . n 
A 1 160 LEU 160 162 162 LEU LEU 1 . n 
A 1 161 LEU 161 163 163 LEU LEU 1 . n 
A 1 162 GLU 162 164 164 GLU GLU 1 . n 
A 1 163 GLY 163 165 165 GLY GLY 1 . n 
A 1 164 ASN 164 166 166 ASN ASN 1 . n 
A 1 165 ALA 165 167 167 ALA ALA 1 . n 
A 1 166 HIS 166 168 168 HIS HIS 1 . n 
A 1 167 TYR 167 169 169 TYR TYR 1 . n 
A 1 168 ARG 168 170 170 ARG ARG 1 . n 
A 1 169 CYS 169 171 171 CYS CYS 1 . n 
A 1 170 ASP 170 172 172 ASP ASP 1 . n 
A 1 171 PHE 171 173 173 PHE PHE 1 . n 
A 1 172 ARG 172 174 174 ARG ARG 1 . n 
A 1 173 THR 173 175 175 THR THR 1 . n 
A 1 174 THR 174 176 176 THR THR 1 . n 
A 1 175 TYR 175 177 177 TYR TYR 1 . n 
A 1 176 LYS 176 178 178 LYS LYS 1 . n 
A 1 177 ALA 177 179 179 ALA ALA 1 . n 
A 1 178 LYS 178 180 180 LYS LYS 1 . n 
A 1 179 GLU 179 181 181 GLU GLU 1 . n 
A 1 180 LYS 180 182 182 LYS LYS 1 . n 
A 1 181 GLY 181 183 183 GLY GLY 1 . n 
A 1 182 VAL 182 184 184 VAL VAL 1 . n 
A 1 183 LYS 183 185 185 LYS LYS 1 . n 
A 1 184 LEU 184 186 186 LEU LEU 1 . n 
A 1 185 PRO 185 187 187 PRO PRO 1 . n 
A 1 186 GLY 186 188 188 GLY GLY 1 . n 
A 1 187 ALA 187 189 189 ALA ALA 1 . n 
A 1 188 HIS 188 190 190 HIS HIS 1 . n 
A 1 189 PHE 189 191 191 PHE PHE 1 . n 
A 1 190 VAL 190 192 192 VAL VAL 1 . n 
A 1 191 ASP 191 193 193 ASP ASP 1 . n 
A 1 192 HIS 192 194 194 HIS HIS 1 . n 
A 1 193 CYS 193 195 195 CYS CYS 1 . n 
A 1 194 ILE 194 196 196 ILE ILE 1 . n 
A 1 195 GLU 195 197 197 GLU GLU 1 . n 
A 1 196 ILE 196 198 198 ILE ILE 1 . n 
A 1 197 LEU 197 199 199 LEU LEU 1 . n 
A 1 198 SER 198 200 200 SER SER 1 . n 
A 1 199 HIS 199 201 201 HIS HIS 1 . n 
A 1 200 ASP 200 202 202 ASP ASP 1 . n 
A 1 201 LYS 201 203 203 LYS LYS 1 . n 
A 1 202 ASP 202 204 204 ASP ASP 1 . n 
A 1 203 TYR 203 205 205 TYR TYR 1 . n 
A 1 204 ASN 204 206 206 ASN ASN 1 . n 
A 1 205 LYS 205 207 207 LYS LYS 1 . n 
A 1 206 VAL 206 208 208 VAL VAL 1 . n 
A 1 207 LYS 207 209 209 LYS LYS 1 . n 
A 1 208 LEU 208 210 210 LEU LEU 1 . n 
A 1 209 TYR 209 211 211 TYR TYR 1 . n 
A 1 210 GLU 210 212 212 GLU GLU 1 . n 
A 1 211 HIS 211 213 213 HIS HIS 1 . n 
A 1 212 ALA 212 214 214 ALA ALA 1 . n 
A 1 213 VAL 213 215 215 VAL VAL 1 . n 
A 1 214 ALA 214 216 216 ALA ALA 1 . n 
A 1 215 HIS 215 217 217 HIS HIS 1 . n 
A 1 216 SER 216 218 218 SER SER 1 . n 
A 1 217 GLY 217 219 219 GLY GLY 1 . n 
A 1 218 LEU 218 220 220 LEU LEU 1 . n 
A 1 219 PRO 219 221 221 PRO PRO 1 . n 
A 1 220 ASN 220 222 ?   ?   ?   1 . n 
B 1 1   MET 1   1   ?   ?   ?   2 . n 
B 1 2   SER 2   2   2   SER SER 2 . n 
B 1 3   ALA 3   3   3   ALA ALA 2 . n 
B 1 4   ILE 4   4   4   ILE ILE 2 . n 
B 1 5   LYS 5   5   5   LYS LYS 2 . n 
B 1 6   PRO 6   6   6   PRO PRO 2 . n 
B 1 7   ASP 7   7   7   ASP ASP 2 . n 
B 1 8   MET 8   8   8   MET MET 2 . n 
B 1 9   LYS 9   9   9   LYS LYS 2 . n 
B 1 10  ILE 10  10  10  ILE ILE 2 . n 
B 1 11  LYS 11  11  11  LYS LYS 2 . n 
B 1 12  LEU 12  12  12  LEU LEU 2 . n 
B 1 13  ARG 13  13  13  ARG ARG 2 . n 
B 1 14  MET 14  14  14  MET MET 2 . n 
B 1 15  GLU 15  15  15  GLU GLU 2 . n 
B 1 16  GLY 16  16  16  GLY GLY 2 . n 
B 1 17  ASN 17  17  17  ASN ASN 2 . n 
B 1 18  VAL 18  18  18  VAL VAL 2 . n 
B 1 19  ASN 19  19  19  ASN ASN 2 . n 
B 1 20  GLY 20  20  20  GLY GLY 2 . n 
B 1 21  HIS 21  21  21  HIS HIS 2 . n 
B 1 22  HIS 22  22  22  HIS HIS 2 . n 
B 1 23  PHE 23  23  23  PHE PHE 2 . n 
B 1 24  VAL 24  24  24  VAL VAL 2 . n 
B 1 25  ILE 25  25  25  ILE ILE 2 . n 
B 1 26  ASP 26  26  26  ASP ASP 2 . n 
B 1 27  GLY 27  27  27  GLY GLY 2 . n 
B 1 28  ASP 28  28  28  ASP ASP 2 . n 
B 1 29  GLY 29  29  29  GLY GLY 2 . n 
B 1 30  THR 30  30  30  THR THR 2 . n 
B 1 31  GLY 31  31  31  GLY GLY 2 . n 
B 1 32  LYS 32  32  32  LYS LYS 2 . n 
B 1 33  PRO 33  33  33  PRO PRO 2 . n 
B 1 34  PHE 34  34  34  PHE PHE 2 . n 
B 1 35  GLU 35  35  35  GLU GLU 2 . n 
B 1 36  GLY 36  36  36  GLY GLY 2 . n 
B 1 37  LYS 37  37  37  LYS LYS 2 . n 
B 1 38  GLN 38  38  38  GLN GLN 2 . n 
B 1 39  SER 39  39  39  SER SER 2 . n 
B 1 40  MET 40  40  40  MET MET 2 . n 
B 1 41  ASP 41  41  41  ASP ASP 2 . n 
B 1 42  LEU 42  42  42  LEU LEU 2 . n 
B 1 43  GLU 43  43  43  GLU GLU 2 . n 
B 1 44  VAL 44  44  44  VAL VAL 2 . n 
B 1 45  LYS 45  45  45  LYS LYS 2 . n 
B 1 46  GLU 46  46  46  GLU GLU 2 . n 
B 1 47  GLY 47  47  47  GLY GLY 2 . n 
B 1 48  GLY 48  48  48  GLY GLY 2 . n 
B 1 49  PRO 49  49  49  PRO PRO 2 . n 
B 1 50  LEU 50  50  50  LEU LEU 2 . n 
B 1 51  PRO 51  51  51  PRO PRO 2 . n 
B 1 52  PHE 52  52  52  PHE PHE 2 . n 
B 1 53  ALA 53  53  53  ALA ALA 2 . n 
B 1 54  PHE 54  54  54  PHE PHE 2 . n 
B 1 55  ASP 55  55  55  ASP ASP 2 . n 
B 1 56  ILE 56  56  56  ILE ILE 2 . n 
B 1 57  LEU 57  57  57  LEU LEU 2 . n 
B 1 58  THR 58  58  58  THR THR 2 . n 
B 1 59  THR 59  59  59  THR THR 2 . n 
B 1 60  ALA 60  60  60  ALA ALA 2 . n 
B 1 61  PHE 61  61  61  PHE PHE 2 . n 
B 1 62  PIA 62  64  64  PIA PIA 2 . n 
B 1 63  ASN 63  65  65  ASN ASN 2 . n 
B 1 64  ARG 64  66  66  ARG ARG 2 . n 
B 1 65  VAL 65  67  67  VAL VAL 2 . n 
B 1 66  PHE 66  68  68  PHE PHE 2 . n 
B 1 67  ALA 67  69  69  ALA ALA 2 . n 
B 1 68  LYS 68  70  70  LYS LYS 2 . n 
B 1 69  TYR 69  71  71  TYR TYR 2 . n 
B 1 70  PRO 70  72  72  PRO PRO 2 . n 
B 1 71  ASP 71  73  73  ASP ASP 2 . n 
B 1 72  ASN 72  74  74  ASN ASN 2 . n 
B 1 73  ILE 73  75  75  ILE ILE 2 . n 
B 1 74  GLN 74  76  76  GLN GLN 2 . n 
B 1 75  ASP 75  77  77  ASP ASP 2 . n 
B 1 76  TYR 76  78  78  TYR TYR 2 . n 
B 1 77  PHE 77  79  79  PHE PHE 2 . n 
B 1 78  LYS 78  80  80  LYS LYS 2 . n 
B 1 79  GLN 79  81  81  GLN GLN 2 . n 
B 1 80  SER 80  82  82  SER SER 2 . n 
B 1 81  PHE 81  83  83  PHE PHE 2 . n 
B 1 82  PRO 82  84  84  PRO PRO 2 . n 
B 1 83  LYS 83  85  85  LYS LYS 2 . n 
B 1 84  GLY 84  86  86  GLY GLY 2 . n 
B 1 85  TYR 85  87  87  TYR TYR 2 . n 
B 1 86  SER 86  88  88  SER SER 2 . n 
B 1 87  TRP 87  89  89  TRP TRP 2 . n 
B 1 88  GLU 88  90  90  GLU GLU 2 . n 
B 1 89  ARG 89  91  91  ARG ARG 2 . n 
B 1 90  SER 90  92  92  SER SER 2 . n 
B 1 91  LEU 91  93  93  LEU LEU 2 . n 
B 1 92  THR 92  94  94  THR THR 2 . n 
B 1 93  PHE 93  95  95  PHE PHE 2 . n 
B 1 94  GLU 94  96  96  GLU GLU 2 . n 
B 1 95  ASP 95  97  97  ASP ASP 2 . n 
B 1 96  GLY 96  98  98  GLY GLY 2 . n 
B 1 97  GLY 97  99  99  GLY GLY 2 . n 
B 1 98  ILE 98  100 100 ILE ILE 2 . n 
B 1 99  CYS 99  101 101 CYS CYS 2 . n 
B 1 100 ASN 100 102 102 ASN ASN 2 . n 
B 1 101 ALA 101 103 103 ALA ALA 2 . n 
B 1 102 ARG 102 104 104 ARG ARG 2 . n 
B 1 103 ASN 103 105 105 ASN ASN 2 . n 
B 1 104 ASP 104 106 106 ASP ASP 2 . n 
B 1 105 ILE 105 107 107 ILE ILE 2 . n 
B 1 106 THR 106 108 108 THR THR 2 . n 
B 1 107 MET 107 109 109 MET MET 2 . n 
B 1 108 GLU 108 110 110 GLU GLU 2 . n 
B 1 109 GLY 109 111 111 GLY GLY 2 . n 
B 1 110 ASP 110 112 112 ASP ASP 2 . n 
B 1 111 THR 111 113 113 THR THR 2 . n 
B 1 112 PHE 112 114 114 PHE PHE 2 . n 
B 1 113 TYR 113 115 115 TYR TYR 2 . n 
B 1 114 ASN 114 116 116 ASN ASN 2 . n 
B 1 115 LYS 115 117 117 LYS LYS 2 . n 
B 1 116 VAL 116 118 118 VAL VAL 2 . n 
B 1 117 ARG 117 119 119 ARG ARG 2 . n 
B 1 118 PHE 118 120 120 PHE PHE 2 . n 
B 1 119 TYR 119 121 121 TYR TYR 2 . n 
B 1 120 GLY 120 122 122 GLY GLY 2 . n 
B 1 121 THR 121 123 123 THR THR 2 . n 
B 1 122 ASN 122 124 124 ASN ASN 2 . n 
B 1 123 PHE 123 125 125 PHE PHE 2 . n 
B 1 124 PRO 124 126 126 PRO PRO 2 . n 
B 1 125 ALA 125 127 127 ALA ALA 2 . n 
B 1 126 ASN 126 128 128 ASN ASN 2 . n 
B 1 127 GLY 127 129 129 GLY GLY 2 . n 
B 1 128 PRO 128 130 130 PRO PRO 2 . n 
B 1 129 VAL 129 131 131 VAL VAL 2 . n 
B 1 130 MET 130 132 132 MET MET 2 . n 
B 1 131 GLN 131 133 133 GLN GLN 2 . n 
B 1 132 LYS 132 134 134 LYS LYS 2 . n 
B 1 133 LYS 133 135 135 LYS LYS 2 . n 
B 1 134 THR 134 136 136 THR THR 2 . n 
B 1 135 LEU 135 137 137 LEU LEU 2 . n 
B 1 136 LYS 136 138 138 LYS LYS 2 . n 
B 1 137 TRP 137 139 139 TRP TRP 2 . n 
B 1 138 GLU 138 140 140 GLU GLU 2 . n 
B 1 139 PRO 139 141 141 PRO PRO 2 . n 
B 1 140 SER 140 142 142 SER SER 2 . n 
B 1 141 THR 141 143 143 THR THR 2 . n 
B 1 142 GLU 142 144 144 GLU GLU 2 . n 
B 1 143 LYS 143 145 145 LYS LYS 2 . n 
B 1 144 MET 144 146 146 MET MET 2 . n 
B 1 145 TYR 145 147 147 TYR TYR 2 . n 
B 1 146 VAL 146 148 148 VAL VAL 2 . n 
B 1 147 ARG 147 149 149 ARG ARG 2 . n 
B 1 148 ASP 148 150 150 ASP ASP 2 . n 
B 1 149 GLY 149 151 151 GLY GLY 2 . n 
B 1 150 VAL 150 152 152 VAL VAL 2 . n 
B 1 151 LEU 151 153 153 LEU LEU 2 . n 
B 1 152 THR 152 154 154 THR THR 2 . n 
B 1 153 GLY 153 155 155 GLY GLY 2 . n 
B 1 154 ASP 154 156 156 ASP ASP 2 . n 
B 1 155 VAL 155 157 157 VAL VAL 2 . n 
B 1 156 GLU 156 158 158 GLU GLU 2 . n 
B 1 157 THR 157 159 159 THR THR 2 . n 
B 1 158 ALA 158 160 160 ALA ALA 2 . n 
B 1 159 LEU 159 161 161 LEU LEU 2 . n 
B 1 160 LEU 160 162 162 LEU LEU 2 . n 
B 1 161 LEU 161 163 163 LEU LEU 2 . n 
B 1 162 GLU 162 164 164 GLU GLU 2 . n 
B 1 163 GLY 163 165 165 GLY GLY 2 . n 
B 1 164 ASN 164 166 166 ASN ASN 2 . n 
B 1 165 ALA 165 167 167 ALA ALA 2 . n 
B 1 166 HIS 166 168 168 HIS HIS 2 . n 
B 1 167 TYR 167 169 169 TYR TYR 2 . n 
B 1 168 ARG 168 170 170 ARG ARG 2 . n 
B 1 169 CYS 169 171 171 CYS CYS 2 . n 
B 1 170 ASP 170 172 172 ASP ASP 2 . n 
B 1 171 PHE 171 173 173 PHE PHE 2 . n 
B 1 172 ARG 172 174 174 ARG ARG 2 . n 
B 1 173 THR 173 175 175 THR THR 2 . n 
B 1 174 THR 174 176 176 THR THR 2 . n 
B 1 175 TYR 175 177 177 TYR TYR 2 . n 
B 1 176 LYS 176 178 178 LYS LYS 2 . n 
B 1 177 ALA 177 179 179 ALA ALA 2 . n 
B 1 178 LYS 178 180 180 LYS LYS 2 . n 
B 1 179 GLU 179 181 181 GLU GLU 2 . n 
B 1 180 LYS 180 182 182 LYS LYS 2 . n 
B 1 181 GLY 181 183 183 GLY GLY 2 . n 
B 1 182 VAL 182 184 184 VAL VAL 2 . n 
B 1 183 LYS 183 185 185 LYS LYS 2 . n 
B 1 184 LEU 184 186 186 LEU LEU 2 . n 
B 1 185 PRO 185 187 187 PRO PRO 2 . n 
B 1 186 GLY 186 188 188 GLY GLY 2 . n 
B 1 187 ALA 187 189 189 ALA ALA 2 . n 
B 1 188 HIS 188 190 190 HIS HIS 2 . n 
B 1 189 PHE 189 191 191 PHE PHE 2 . n 
B 1 190 VAL 190 192 192 VAL VAL 2 . n 
B 1 191 ASP 191 193 193 ASP ASP 2 . n 
B 1 192 HIS 192 194 194 HIS HIS 2 . n 
B 1 193 CYS 193 195 195 CYS CYS 2 . n 
B 1 194 ILE 194 196 196 ILE ILE 2 . n 
B 1 195 GLU 195 197 197 GLU GLU 2 . n 
B 1 196 ILE 196 198 198 ILE ILE 2 . n 
B 1 197 LEU 197 199 199 LEU LEU 2 . n 
B 1 198 SER 198 200 200 SER SER 2 . n 
B 1 199 HIS 199 201 201 HIS HIS 2 . n 
B 1 200 ASP 200 202 202 ASP ASP 2 . n 
B 1 201 LYS 201 203 203 LYS LYS 2 . n 
B 1 202 ASP 202 204 204 ASP ASP 2 . n 
B 1 203 TYR 203 205 205 TYR TYR 2 . n 
B 1 204 ASN 204 206 206 ASN ASN 2 . n 
B 1 205 LYS 205 207 207 LYS LYS 2 . n 
B 1 206 VAL 206 208 208 VAL VAL 2 . n 
B 1 207 LYS 207 209 209 LYS LYS 2 . n 
B 1 208 LEU 208 210 210 LEU LEU 2 . n 
B 1 209 TYR 209 211 211 TYR TYR 2 . n 
B 1 210 GLU 210 212 212 GLU GLU 2 . n 
B 1 211 HIS 211 213 213 HIS HIS 2 . n 
B 1 212 ALA 212 214 214 ALA ALA 2 . n 
B 1 213 VAL 213 215 215 VAL VAL 2 . n 
B 1 214 ALA 214 216 216 ALA ALA 2 . n 
B 1 215 HIS 215 217 217 HIS HIS 2 . n 
B 1 216 SER 216 218 218 SER SER 2 . n 
B 1 217 GLY 217 219 219 GLY GLY 2 . n 
B 1 218 LEU 218 220 220 LEU LEU 2 . n 
B 1 219 PRO 219 221 221 PRO PRO 2 . n 
B 1 220 ASN 220 222 ?   ?   ?   2 . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        PIA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   PIA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 SO4 1   301 1   SO4 SO4 1 . 
D 2 SO4 1   302 2   SO4 SO4 1 . 
E 2 SO4 1   303 3   SO4 SO4 1 . 
F 2 SO4 1   304 1   SO4 SO4 1 . 
G 3 GOL 1   301 301 GOL GOL 2 . 
H 4 HOH 1   401 334 HOH HOH 1 . 
H 4 HOH 2   402 400 HOH HOH 1 . 
H 4 HOH 3   403 392 HOH HOH 1 . 
H 4 HOH 4   404 358 HOH HOH 1 . 
H 4 HOH 5   405 355 HOH HOH 1 . 
H 4 HOH 6   406 376 HOH HOH 1 . 
H 4 HOH 7   407 116 HOH HOH 1 . 
H 4 HOH 8   408 328 HOH HOH 1 . 
H 4 HOH 9   409 346 HOH HOH 1 . 
H 4 HOH 10  410 350 HOH HOH 1 . 
H 4 HOH 11  411 401 HOH HOH 1 . 
H 4 HOH 12  412 56  HOH HOH 1 . 
H 4 HOH 13  413 398 HOH HOH 1 . 
H 4 HOH 14  414 366 HOH HOH 1 . 
H 4 HOH 15  415 106 HOH HOH 1 . 
H 4 HOH 16  416 9   HOH HOH 1 . 
H 4 HOH 17  417 41  HOH HOH 1 . 
H 4 HOH 18  418 245 HOH HOH 1 . 
H 4 HOH 19  419 390 HOH HOH 1 . 
H 4 HOH 20  420 365 HOH HOH 1 . 
H 4 HOH 21  421 179 HOH HOH 1 . 
H 4 HOH 22  422 367 HOH HOH 1 . 
H 4 HOH 23  423 74  HOH HOH 1 . 
H 4 HOH 24  424 168 HOH HOH 1 . 
H 4 HOH 25  425 140 HOH HOH 1 . 
H 4 HOH 26  426 64  HOH HOH 1 . 
H 4 HOH 27  427 68  HOH HOH 1 . 
H 4 HOH 28  428 378 HOH HOH 1 . 
H 4 HOH 29  429 399 HOH HOH 1 . 
H 4 HOH 30  430 27  HOH HOH 1 . 
H 4 HOH 31  431 121 HOH HOH 1 . 
H 4 HOH 32  432 40  HOH HOH 1 . 
H 4 HOH 33  433 29  HOH HOH 1 . 
H 4 HOH 34  434 20  HOH HOH 1 . 
H 4 HOH 35  435 143 HOH HOH 1 . 
H 4 HOH 36  436 61  HOH HOH 1 . 
H 4 HOH 37  437 23  HOH HOH 1 . 
H 4 HOH 38  438 63  HOH HOH 1 . 
H 4 HOH 39  439 326 HOH HOH 1 . 
H 4 HOH 40  440 163 HOH HOH 1 . 
H 4 HOH 41  441 22  HOH HOH 1 . 
H 4 HOH 42  442 387 HOH HOH 1 . 
H 4 HOH 43  443 216 HOH HOH 1 . 
H 4 HOH 44  444 34  HOH HOH 1 . 
H 4 HOH 45  445 84  HOH HOH 1 . 
H 4 HOH 46  446 339 HOH HOH 1 . 
H 4 HOH 47  447 46  HOH HOH 1 . 
H 4 HOH 48  448 109 HOH HOH 1 . 
H 4 HOH 49  449 23  HOH HOH 1 . 
H 4 HOH 50  450 115 HOH HOH 1 . 
H 4 HOH 51  451 173 HOH HOH 1 . 
H 4 HOH 52  452 35  HOH HOH 1 . 
H 4 HOH 53  453 50  HOH HOH 1 . 
H 4 HOH 54  454 12  HOH HOH 1 . 
H 4 HOH 55  455 16  HOH HOH 1 . 
H 4 HOH 56  456 16  HOH HOH 1 . 
H 4 HOH 57  457 59  HOH HOH 1 . 
H 4 HOH 58  458 54  HOH HOH 1 . 
H 4 HOH 59  459 1   HOH HOH 1 . 
H 4 HOH 60  460 36  HOH HOH 1 . 
H 4 HOH 61  461 73  HOH HOH 1 . 
H 4 HOH 62  462 351 HOH HOH 1 . 
H 4 HOH 63  463 64  HOH HOH 1 . 
H 4 HOH 64  464 154 HOH HOH 1 . 
H 4 HOH 65  465 17  HOH HOH 1 . 
H 4 HOH 66  466 363 HOH HOH 1 . 
H 4 HOH 67  467 101 HOH HOH 1 . 
H 4 HOH 68  468 86  HOH HOH 1 . 
H 4 HOH 69  469 172 HOH HOH 1 . 
H 4 HOH 70  470 54  HOH HOH 1 . 
H 4 HOH 71  471 137 HOH HOH 1 . 
H 4 HOH 72  472 13  HOH HOH 1 . 
H 4 HOH 73  473 102 HOH HOH 1 . 
H 4 HOH 74  474 73  HOH HOH 1 . 
H 4 HOH 75  475 162 HOH HOH 1 . 
H 4 HOH 76  476 13  HOH HOH 1 . 
H 4 HOH 77  477 77  HOH HOH 1 . 
H 4 HOH 78  478 38  HOH HOH 1 . 
H 4 HOH 79  479 119 HOH HOH 1 . 
H 4 HOH 80  480 31  HOH HOH 1 . 
H 4 HOH 81  481 104 HOH HOH 1 . 
H 4 HOH 82  482 4   HOH HOH 1 . 
H 4 HOH 83  483 107 HOH HOH 1 . 
H 4 HOH 84  484 69  HOH HOH 1 . 
H 4 HOH 85  485 164 HOH HOH 1 . 
H 4 HOH 86  486 50  HOH HOH 1 . 
H 4 HOH 87  487 24  HOH HOH 1 . 
H 4 HOH 88  488 3   HOH HOH 1 . 
H 4 HOH 89  489 30  HOH HOH 1 . 
H 4 HOH 90  490 6   HOH HOH 1 . 
H 4 HOH 91  491 12  HOH HOH 1 . 
H 4 HOH 92  492 215 HOH HOH 1 . 
H 4 HOH 93  493 295 HOH HOH 1 . 
H 4 HOH 94  494 135 HOH HOH 1 . 
H 4 HOH 95  495 134 HOH HOH 1 . 
H 4 HOH 96  496 194 HOH HOH 1 . 
H 4 HOH 97  497 45  HOH HOH 1 . 
H 4 HOH 98  498 121 HOH HOH 1 . 
H 4 HOH 99  499 145 HOH HOH 1 . 
H 4 HOH 100 500 132 HOH HOH 1 . 
H 4 HOH 101 501 21  HOH HOH 1 . 
H 4 HOH 102 502 65  HOH HOH 1 . 
H 4 HOH 103 503 37  HOH HOH 1 . 
H 4 HOH 104 504 359 HOH HOH 1 . 
H 4 HOH 105 505 130 HOH HOH 1 . 
H 4 HOH 106 506 7   HOH HOH 1 . 
H 4 HOH 107 507 368 HOH HOH 1 . 
H 4 HOH 108 508 123 HOH HOH 1 . 
H 4 HOH 109 509 86  HOH HOH 1 . 
H 4 HOH 110 510 62  HOH HOH 1 . 
H 4 HOH 111 511 186 HOH HOH 1 . 
H 4 HOH 112 512 14  HOH HOH 1 . 
H 4 HOH 113 513 32  HOH HOH 1 . 
H 4 HOH 114 514 21  HOH HOH 1 . 
H 4 HOH 115 515 366 HOH HOH 1 . 
H 4 HOH 116 516 108 HOH HOH 1 . 
H 4 HOH 117 517 44  HOH HOH 1 . 
H 4 HOH 118 518 116 HOH HOH 1 . 
H 4 HOH 119 519 71  HOH HOH 1 . 
H 4 HOH 120 520 109 HOH HOH 1 . 
H 4 HOH 121 521 49  HOH HOH 1 . 
H 4 HOH 122 522 53  HOH HOH 1 . 
H 4 HOH 123 523 44  HOH HOH 1 . 
H 4 HOH 124 524 357 HOH HOH 1 . 
H 4 HOH 125 525 92  HOH HOH 1 . 
H 4 HOH 126 526 29  HOH HOH 1 . 
H 4 HOH 127 527 174 HOH HOH 1 . 
H 4 HOH 128 528 344 HOH HOH 1 . 
H 4 HOH 129 529 364 HOH HOH 1 . 
H 4 HOH 130 530 164 HOH HOH 1 . 
H 4 HOH 131 531 266 HOH HOH 1 . 
H 4 HOH 132 532 47  HOH HOH 1 . 
H 4 HOH 133 533 82  HOH HOH 1 . 
H 4 HOH 134 534 98  HOH HOH 1 . 
H 4 HOH 135 535 197 HOH HOH 1 . 
H 4 HOH 136 536 395 HOH HOH 1 . 
H 4 HOH 137 537 35  HOH HOH 1 . 
H 4 HOH 138 538 182 HOH HOH 1 . 
H 4 HOH 139 539 1   HOH HOH 1 . 
H 4 HOH 140 540 379 HOH HOH 1 . 
H 4 HOH 141 541 380 HOH HOH 1 . 
H 4 HOH 142 542 27  HOH HOH 1 . 
H 4 HOH 143 543 8   HOH HOH 1 . 
H 4 HOH 144 544 48  HOH HOH 1 . 
H 4 HOH 145 545 22  HOH HOH 1 . 
H 4 HOH 146 546 85  HOH HOH 1 . 
H 4 HOH 147 547 364 HOH HOH 1 . 
H 4 HOH 148 548 362 HOH HOH 1 . 
H 4 HOH 149 549 56  HOH HOH 1 . 
H 4 HOH 150 550 66  HOH HOH 1 . 
H 4 HOH 151 551 151 HOH HOH 1 . 
H 4 HOH 152 552 208 HOH HOH 1 . 
H 4 HOH 153 553 214 HOH HOH 1 . 
H 4 HOH 154 554 96  HOH HOH 1 . 
H 4 HOH 155 555 233 HOH HOH 1 . 
H 4 HOH 156 556 243 HOH HOH 1 . 
H 4 HOH 157 557 161 HOH HOH 1 . 
H 4 HOH 158 558 83  HOH HOH 1 . 
H 4 HOH 159 559 333 HOH HOH 1 . 
H 4 HOH 160 560 393 HOH HOH 1 . 
H 4 HOH 161 561 178 HOH HOH 1 . 
H 4 HOH 162 562 232 HOH HOH 1 . 
H 4 HOH 163 563 288 HOH HOH 1 . 
H 4 HOH 164 564 384 HOH HOH 1 . 
H 4 HOH 165 565 49  HOH HOH 1 . 
H 4 HOH 166 566 155 HOH HOH 1 . 
H 4 HOH 167 567 184 HOH HOH 1 . 
H 4 HOH 168 568 368 HOH HOH 1 . 
H 4 HOH 169 569 230 HOH HOH 1 . 
H 4 HOH 170 570 396 HOH HOH 1 . 
H 4 HOH 171 571 53  HOH HOH 1 . 
H 4 HOH 172 572 113 HOH HOH 1 . 
H 4 HOH 173 573 273 HOH HOH 1 . 
H 4 HOH 174 574 81  HOH HOH 1 . 
H 4 HOH 175 575 126 HOH HOH 1 . 
H 4 HOH 176 576 140 HOH HOH 1 . 
H 4 HOH 177 577 74  HOH HOH 1 . 
H 4 HOH 178 578 291 HOH HOH 1 . 
H 4 HOH 179 579 79  HOH HOH 1 . 
H 4 HOH 180 580 277 HOH HOH 1 . 
H 4 HOH 181 581 353 HOH HOH 1 . 
H 4 HOH 182 582 127 HOH HOH 1 . 
H 4 HOH 183 583 36  HOH HOH 1 . 
H 4 HOH 184 584 397 HOH HOH 1 . 
H 4 HOH 185 585 371 HOH HOH 1 . 
H 4 HOH 186 586 68  HOH HOH 1 . 
H 4 HOH 187 587 58  HOH HOH 1 . 
H 4 HOH 188 588 257 HOH HOH 1 . 
I 4 HOH 1   401 386 HOH HOH 2 . 
I 4 HOH 2   402 341 HOH HOH 2 . 
I 4 HOH 3   403 352 HOH HOH 2 . 
I 4 HOH 4   404 335 HOH HOH 2 . 
I 4 HOH 5   405 20  HOH HOH 2 . 
I 4 HOH 6   406 347 HOH HOH 2 . 
I 4 HOH 7   407 348 HOH HOH 2 . 
I 4 HOH 8   408 367 HOH HOH 2 . 
I 4 HOH 9   409 95  HOH HOH 2 . 
I 4 HOH 10  410 363 HOH HOH 2 . 
I 4 HOH 11  411 381 HOH HOH 2 . 
I 4 HOH 12  412 349 HOH HOH 2 . 
I 4 HOH 13  413 200 HOH HOH 2 . 
I 4 HOH 14  414 103 HOH HOH 2 . 
I 4 HOH 15  415 25  HOH HOH 2 . 
I 4 HOH 16  416 231 HOH HOH 2 . 
I 4 HOH 17  417 183 HOH HOH 2 . 
I 4 HOH 18  418 28  HOH HOH 2 . 
I 4 HOH 19  419 78  HOH HOH 2 . 
I 4 HOH 20  420 46  HOH HOH 2 . 
I 4 HOH 21  421 354 HOH HOH 2 . 
I 4 HOH 22  422 105 HOH HOH 2 . 
I 4 HOH 23  423 391 HOH HOH 2 . 
I 4 HOH 24  424 345 HOH HOH 2 . 
I 4 HOH 25  425 65  HOH HOH 2 . 
I 4 HOH 26  426 356 HOH HOH 2 . 
I 4 HOH 27  427 2   HOH HOH 2 . 
I 4 HOH 28  428 75  HOH HOH 2 . 
I 4 HOH 29  429 211 HOH HOH 2 . 
I 4 HOH 30  430 43  HOH HOH 2 . 
I 4 HOH 31  431 207 HOH HOH 2 . 
I 4 HOH 32  432 41  HOH HOH 2 . 
I 4 HOH 33  433 7   HOH HOH 2 . 
I 4 HOH 34  434 8   HOH HOH 2 . 
I 4 HOH 35  435 187 HOH HOH 2 . 
I 4 HOH 36  436 83  HOH HOH 2 . 
I 4 HOH 37  437 11  HOH HOH 2 . 
I 4 HOH 38  438 55  HOH HOH 2 . 
I 4 HOH 39  439 197 HOH HOH 2 . 
I 4 HOH 40  440 342 HOH HOH 2 . 
I 4 HOH 41  441 383 HOH HOH 2 . 
I 4 HOH 42  442 131 HOH HOH 2 . 
I 4 HOH 43  443 5   HOH HOH 2 . 
I 4 HOH 44  444 15  HOH HOH 2 . 
I 4 HOH 45  445 156 HOH HOH 2 . 
I 4 HOH 46  446 122 HOH HOH 2 . 
I 4 HOH 47  447 185 HOH HOH 2 . 
I 4 HOH 48  448 158 HOH HOH 2 . 
I 4 HOH 49  449 362 HOH HOH 2 . 
I 4 HOH 50  450 360 HOH HOH 2 . 
I 4 HOH 51  451 369 HOH HOH 2 . 
I 4 HOH 52  452 24  HOH HOH 2 . 
I 4 HOH 53  453 25  HOH HOH 2 . 
I 4 HOH 54  454 193 HOH HOH 2 . 
I 4 HOH 55  455 70  HOH HOH 2 . 
I 4 HOH 56  456 51  HOH HOH 2 . 
I 4 HOH 57  457 258 HOH HOH 2 . 
I 4 HOH 58  458 112 HOH HOH 2 . 
I 4 HOH 59  459 59  HOH HOH 2 . 
I 4 HOH 60  460 19  HOH HOH 2 . 
I 4 HOH 61  461 266 HOH HOH 2 . 
I 4 HOH 62  462 26  HOH HOH 2 . 
I 4 HOH 63  463 42  HOH HOH 2 . 
I 4 HOH 64  464 51  HOH HOH 2 . 
I 4 HOH 65  465 382 HOH HOH 2 . 
I 4 HOH 66  466 88  HOH HOH 2 . 
I 4 HOH 67  467 394 HOH HOH 2 . 
I 4 HOH 68  468 34  HOH HOH 2 . 
I 4 HOH 69  469 75  HOH HOH 2 . 
I 4 HOH 70  470 262 HOH HOH 2 . 
I 4 HOH 71  471 139 HOH HOH 2 . 
I 4 HOH 72  472 5   HOH HOH 2 . 
I 4 HOH 73  473 120 HOH HOH 2 . 
I 4 HOH 74  474 355 HOH HOH 2 . 
I 4 HOH 75  475 33  HOH HOH 2 . 
I 4 HOH 76  476 129 HOH HOH 2 . 
I 4 HOH 77  477 11  HOH HOH 2 . 
I 4 HOH 78  478 90  HOH HOH 2 . 
I 4 HOH 79  479 196 HOH HOH 2 . 
I 4 HOH 80  480 45  HOH HOH 2 . 
I 4 HOH 81  481 2   HOH HOH 2 . 
I 4 HOH 82  482 290 HOH HOH 2 . 
I 4 HOH 83  483 274 HOH HOH 2 . 
I 4 HOH 84  484 340 HOH HOH 2 . 
I 4 HOH 85  485 359 HOH HOH 2 . 
I 4 HOH 86  486 124 HOH HOH 2 . 
I 4 HOH 87  487 337 HOH HOH 2 . 
I 4 HOH 88  488 152 HOH HOH 2 . 
I 4 HOH 89  489 10  HOH HOH 2 . 
I 4 HOH 90  490 373 HOH HOH 2 . 
I 4 HOH 91  491 15  HOH HOH 2 . 
I 4 HOH 92  492 353 HOH HOH 2 . 
I 4 HOH 93  493 216 HOH HOH 2 . 
I 4 HOH 94  494 181 HOH HOH 2 . 
I 4 HOH 95  495 60  HOH HOH 2 . 
I 4 HOH 96  496 375 HOH HOH 2 . 
I 4 HOH 97  497 159 HOH HOH 2 . 
I 4 HOH 98  498 18  HOH HOH 2 . 
I 4 HOH 99  499 361 HOH HOH 2 . 
I 4 HOH 100 500 219 HOH HOH 2 . 
I 4 HOH 101 501 77  HOH HOH 2 . 
I 4 HOH 102 502 28  HOH HOH 2 . 
I 4 HOH 103 503 66  HOH HOH 2 . 
I 4 HOH 104 504 357 HOH HOH 2 . 
I 4 HOH 105 505 147 HOH HOH 2 . 
I 4 HOH 106 506 26  HOH HOH 2 . 
I 4 HOH 107 507 332 HOH HOH 2 . 
I 4 HOH 108 508 356 HOH HOH 2 . 
I 4 HOH 109 509 284 HOH HOH 2 . 
I 4 HOH 110 510 110 HOH HOH 2 . 
I 4 HOH 111 511 9   HOH HOH 2 . 
I 4 HOH 112 512 70  HOH HOH 2 . 
I 4 HOH 113 513 212 HOH HOH 2 . 
I 4 HOH 114 514 388 HOH HOH 2 . 
I 4 HOH 115 515 385 HOH HOH 2 . 
I 4 HOH 116 516 142 HOH HOH 2 . 
I 4 HOH 117 517 374 HOH HOH 2 . 
I 4 HOH 118 518 63  HOH HOH 2 . 
I 4 HOH 119 519 354 HOH HOH 2 . 
I 4 HOH 120 520 67  HOH HOH 2 . 
I 4 HOH 121 521 57  HOH HOH 2 . 
I 4 HOH 122 522 267 HOH HOH 2 . 
I 4 HOH 123 523 372 HOH HOH 2 . 
I 4 HOH 124 524 48  HOH HOH 2 . 
I 4 HOH 125 525 97  HOH HOH 2 . 
I 4 HOH 126 526 93  HOH HOH 2 . 
I 4 HOH 127 527 40  HOH HOH 2 . 
I 4 HOH 128 528 18  HOH HOH 2 . 
I 4 HOH 129 529 336 HOH HOH 2 . 
I 4 HOH 130 530 280 HOH HOH 2 . 
I 4 HOH 131 531 278 HOH HOH 2 . 
I 4 HOH 132 532 360 HOH HOH 2 . 
I 4 HOH 133 533 338 HOH HOH 2 . 
I 4 HOH 134 534 365 HOH HOH 2 . 
I 4 HOH 135 535 343 HOH HOH 2 . 
I 4 HOH 136 536 267 HOH HOH 2 . 
I 4 HOH 137 537 117 HOH HOH 2 . 
I 4 HOH 138 538 339 HOH HOH 2 . 
I 4 HOH 139 539 239 HOH HOH 2 . 
I 4 HOH 140 540 275 HOH HOH 2 . 
I 4 HOH 141 541 377 HOH HOH 2 . 
I 4 HOH 142 542 95  HOH HOH 2 . 
I 4 HOH 143 543 166 HOH HOH 2 . 
I 4 HOH 144 544 253 HOH HOH 2 . 
I 4 HOH 145 545 120 HOH HOH 2 . 
I 4 HOH 146 546 99  HOH HOH 2 . 
I 4 HOH 147 547 100 HOH HOH 2 . 
I 4 HOH 148 548 118 HOH HOH 2 . 
I 4 HOH 149 549 260 HOH HOH 2 . 
I 4 HOH 150 550 330 HOH HOH 2 . 
I 4 HOH 151 551 82  HOH HOH 2 . 
I 4 HOH 152 552 331 HOH HOH 2 . 
I 4 HOH 153 553 167 HOH HOH 2 . 
I 4 HOH 154 554 111 HOH HOH 2 . 
I 4 HOH 155 555 389 HOH HOH 2 . 
I 4 HOH 156 556 217 HOH HOH 2 . 
I 4 HOH 157 557 93  HOH HOH 2 . 
I 4 HOH 158 558 169 HOH HOH 2 . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? 5.8.0267 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .        2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? CrystFEL ? ? ? .        3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? REFMAC   ? ? ? .        4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UL1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     39.600 
_cell.length_a_esd                 ? 
_cell.length_b                     74.500 
_cell.length_b_esd                 ? 
_cell.length_c                     78.900 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UL1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UL1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.21 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          ? 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 44.29 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'BATCH MODE' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.4 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2 M lithium sulfate, 0.1 M Tris-Cl, 25 % PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            295 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     290 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 4M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2019-05-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9801 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PETRA III, EMBL c/o DESY BEAMLINE P14 (MX2)' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.9801 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   'P14 (MX2)' 
_diffrn_source.pdbx_synchrotron_site       'PETRA III, EMBL c/o DESY' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       8UL1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.70 
_reflns.d_resolution_low                               78.69 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     1223960 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.278 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                46.6 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          3.114 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.96 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.700 
_reflns_shell.d_res_low                                     1.761 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             14289 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.0486 
_reflns_shell.pdbx_CC_star                                  0.304 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.017 
_refine.aniso_B[1][2]                            -0.000 
_refine.aniso_B[1][3]                            0.000 
_refine.aniso_B[2][2]                            0.020 
_refine.aniso_B[2][3]                            -0.000 
_refine.aniso_B[3][3]                            -0.003 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               27.241 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.966 
_refine.correlation_coeff_Fo_to_Fc_free          0.964 
_refine.details                                  'Hydrogens have not been used' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UL1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.750 
_refine.ls_d_res_low                             54.227 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     23910 
_refine.ls_number_reflns_R_free                  1173 
_refine.ls_number_reflns_R_work                  22737 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.586 
_refine.ls_percent_reflns_R_free                 4.906 
_refine.ls_R_factor_all                          0.187 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       0.1840 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1872 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      0.193 
_refine.ls_wR_factor_R_work                      0.198 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'MASK BULK SOLVENT' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.138 
_refine.pdbx_overall_ESU_R_Free                  0.136 
_refine.pdbx_solvent_vdw_probe_radii             1.200 
_refine.pdbx_solvent_ion_probe_radii             0.800 
_refine.pdbx_solvent_shrinkage_radii             0.800 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             0.009 
_refine.overall_SU_ML                            0.000 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    0.8720 
_refine.pdbx_average_fsc_free                    0.8677 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.750 
_refine_hist.d_res_low                        54.227 
_refine_hist.number_atoms_solvent             346 
_refine_hist.number_atoms_total               3880 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3508 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         26 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.750 1.795  . . 69 1447 85.4566  . . . . 0.400 . . . . . . . . . . . 0.374 
'X-RAY DIFFRACTION' 1.795 1.845  . . 74 1568 96.8160  . . . . 0.359 . . . . . . . . . . . 0.365 
'X-RAY DIFFRACTION' 1.845 1.898  . . 89 1568 98.6897  . . . . 0.347 . . . . . . . . . . . 0.333 
'X-RAY DIFFRACTION' 1.898 1.956  . . 86 1526 99.8142  . . . . 0.309 . . . . . . . . . . . 0.330 
'X-RAY DIFFRACTION' 1.956 2.020  . . 74 1499 99.9365  . . . . 0.245 . . . . . . . . . . . 0.242 
'X-RAY DIFFRACTION' 2.020 2.091  . . 70 1472 100.0000 . . . . 0.222 . . . . . . . . . . . 0.202 
'X-RAY DIFFRACTION' 2.091 2.170  . . 81 1385 100.0000 . . . . 0.194 . . . . . . . . . . . 0.185 
'X-RAY DIFFRACTION' 2.170 2.259  . . 66 1356 100.0000 . . . . 0.197 . . . . . . . . . . . 0.203 
'X-RAY DIFFRACTION' 2.259 2.359  . . 65 1316 100.0000 . . . . 0.179 . . . . . . . . . . . 0.200 
'X-RAY DIFFRACTION' 2.359 2.474  . . 52 1259 100.0000 . . . . 0.181 . . . . . . . . . . . 0.188 
'X-RAY DIFFRACTION' 2.474 2.608  . . 63 1179 100.0000 . . . . 0.192 . . . . . . . . . . . 0.205 
'X-RAY DIFFRACTION' 2.608 2.766  . . 68 1117 100.0000 . . . . 0.179 . . . . . . . . . . . 0.151 
'X-RAY DIFFRACTION' 2.766 2.957  . . 39 1079 100.0000 . . . . 0.172 . . . . . . . . . . . 0.162 
'X-RAY DIFFRACTION' 2.957 3.193  . . 55 1000 100.0000 . . . . 0.165 . . . . . . . . . . . 0.144 
'X-RAY DIFFRACTION' 3.193 3.497  . . 43 928  100.0000 . . . . 0.139 . . . . . . . . . . . 0.144 
'X-RAY DIFFRACTION' 3.497 3.909  . . 59 822  100.0000 . . . . 0.136 . . . . . . . . . . . 0.137 
'X-RAY DIFFRACTION' 3.909 4.512  . . 31 753  100.0000 . . . . 0.132 . . . . . . . . . . . 0.113 
'X-RAY DIFFRACTION' 4.512 5.522  . . 42 640  100.0000 . . . . 0.132 . . . . . . . . . . . 0.144 
'X-RAY DIFFRACTION' 5.522 7.790  . . 28 518  100.0000 . . . . 0.185 . . . . . . . . . . . 0.256 
'X-RAY DIFFRACTION' 7.790 54.227 . . 19 305  100.0000 . . . . 0.227 . . . . . . . . . . . 0.158 
# 
_struct.entry_id                     8UL1 
_struct.title                        'Structure of rsKiiro using SSX after illumination with 0.1 mJ/mm^2 of 405 nm light' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UL1 
_struct_keywords.text            'rsKiiro, FLUORESCENT PROTEIN' 
_struct_keywords.pdbx_keywords   'FLUORESCENT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 2 ? 
F N N 2 ? 
G N N 3 ? 
H N N 4 ? 
I N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    8UL1 
_struct_ref.pdbx_db_accession          8UL1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UL1 1 1 ? 220 ? 8UL1 1 ? 222 ? 1 222 
2 1 8UL1 2 1 ? 220 ? 8UL1 1 ? 222 ? 1 222 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,D,E,F,H 
2 1 B,G,I       
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale both ? A PHE 61 C  ? ? ? 1_555 A PIA 62 N1 ? ? 1 PHE 61 1 PIA 64 1_555 ? ? ? ? ? ? ? 1.027 ? ? 
covale2 covale both ? A PIA 62 C3 ? ? ? 1_555 A ASN 63 N  ? ? 1 PIA 64 1 ASN 65 1_555 ? ? ? ? ? ? ? 0.987 ? ? 
covale3 covale both ? B PHE 61 C  ? ? ? 1_555 B PIA 62 N1 ? ? 2 PHE 61 2 PIA 64 1_555 ? ? ? ? ? ? ? 1.475 ? ? 
covale4 covale both ? B PIA 62 C3 ? ? ? 1_555 B ASN 63 N  ? ? 2 PIA 64 2 ASN 65 1_555 ? ? ? ? ? ? ? 1.668 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 PIA A 62 ? . . . . PIA 1 64 ? 1_555 . . . . . . . 'ALA, TYR, GLY' 1 PIA None Chromophore/chromophore-like 
2 PIA B 62 ? . . . . PIA 2 64 ? 1_555 . . . . . . . 'ALA, TYR, GLY' 1 PIA None Chromophore/chromophore-like 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLY 48 A . ? GLY 48 1 PRO 49 A ? PRO 49 1 1 -0.30 
2 PHE 81 A . ? PHE 83 1 PRO 82 A ? PRO 84 1 1 10.57 
3 GLY 48 B . ? GLY 48 2 PRO 49 B ? PRO 49 2 1 -3.85 
4 PHE 81 B . ? PHE 83 2 PRO 82 B ? PRO 84 2 1 13.01 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2  ? 
AA2 ? 10 ? 
AA3 ? 2  ? 
AA4 ? 2  ? 
AA5 ? 2  ? 
AA6 ? 2  ? 
AA7 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? parallel      
AA2 1 6  ? parallel      
AA2 1 7  ? anti-parallel 
AA2 2 6  ? anti-parallel 
AA2 2 7  ? parallel      
AA2 2 10 ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 3 8  ? parallel      
AA2 3 9  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA2 4 9  ? parallel      
AA2 5 7  ? anti-parallel 
AA2 5 9  ? anti-parallel 
AA2 5 10 ? parallel      
AA2 8 9  ? anti-parallel 
AA3 1 2  ? parallel      
AA4 1 2  ? parallel      
AA5 1 2  ? parallel      
AA6 1 2  ? parallel      
AA7 1 2  ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  ALA A 3   ? ILE A 4   ? ALA 1 3   ILE 1 4   
AA1 2  ALA B 3   ? ILE B 4   ? ALA 2 3   ILE 2 4   
AA2 1  ASP A 7   ? GLY A 31  ? ASP 1 7   GLY 1 31  
AA2 2  PHE A 34  ? GLY A 47  ? PHE 1 34  GLY 1 47  
AA2 3  LYS A 83  ? ASN A 122 ? LYS 1 85  ASN 1 124 
AA2 4  SER A 140 ? LYS A 183 ? SER 1 142 LYS 1 185 
AA2 5  GLY A 186 ? GLY A 217 ? GLY 1 188 GLY 1 219 
AA2 6  ASP B 7   ? GLY B 31  ? ASP 2 7   GLY 2 31  
AA2 7  PHE B 34  ? GLY B 47  ? PHE 2 34  GLY 2 47  
AA2 8  LYS B 83  ? ASN B 122 ? LYS 2 85  ASN 2 124 
AA2 9  SER B 140 ? LYS B 183 ? SER 2 142 LYS 2 185 
AA2 10 GLY B 186 ? GLY B 217 ? GLY 2 188 GLY 2 219 
AA3 1  PHE A 52  ? ALA A 60  ? PHE 1 52  ALA 1 60  
AA3 2  PHE B 52  ? ALA B 60  ? PHE 2 52  ALA 2 60  
AA4 1  ARG A 64  ? LYS A 68  ? ARG 1 66  LYS 1 70  
AA4 2  ARG B 64  ? LYS B 68  ? ARG 2 66  LYS 2 70  
AA5 1  ASP A 71  ? SER A 80  ? ASP 1 73  SER 1 82  
AA5 2  ASP B 71  ? SER B 80  ? ASP 2 73  SER 2 82  
AA6 1  ALA A 125 ? ASN A 126 ? ALA 1 127 ASN 1 128 
AA6 2  ALA B 125 ? ASN B 126 ? ALA 2 127 ASN 2 128 
AA7 1  VAL A 129 ? TRP A 137 ? VAL 1 131 TRP 1 139 
AA7 2  VAL B 129 ? TRP B 137 ? VAL 2 131 TRP 2 139 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  N ILE A 4   ? N ILE 1 4   O ALA B 3   ? O ALA 2 3   
AA2 1 6  N ASP A 7   ? N ASP 1 7   O MET B 8   ? O MET 2 8   
AA2 1 7  O ASP A 28  ? O ASP 1 28  N ASP B 41  ? N ASP 2 41  
AA2 2 6  O ASP A 41  ? O ASP 1 41  N ASP B 28  ? N ASP 2 28  
AA2 2 7  N GLU A 35  ? N GLU 1 35  O GLY B 36  ? O GLY 2 36  
AA2 2 10 O LEU A 42  ? O LEU 1 42  N VAL B 206 ? N VAL 2 208 
AA2 3 4  O GLU A 88  ? O GLU 1 90  N THR A 174 ? N THR 1 176 
AA2 3 8  N CYS A 99  ? N CYS 1 101 O ASN B 100 ? O ASN 2 102 
AA2 3 9  O SER A 86  ? O SER 1 88  N LYS B 176 ? N LYS 2 178 
AA2 4 5  N MET A 144 ? N MET 1 146 O HIS A 188 ? O HIS 1 190 
AA2 4 9  N GLY A 163 ? N GLY 1 165 O ASN B 164 ? O ASN 2 166 
AA2 5 7  O VAL A 206 ? O VAL 1 208 N LEU B 42  ? N LEU 2 42  
AA2 5 9  N VAL A 190 ? N VAL 1 192 O GLU B 142 ? O GLU 2 144 
AA2 5 10 N ILE A 194 ? N ILE 1 196 O CYS B 193 ? O CYS 2 195 
AA2 8 9  O SER B 86  ? O SER 2 88  N LYS B 176 ? N LYS 2 178 
AA3 1 2  N ALA A 60  ? N ALA 1 60  O THR B 59  ? O THR 2 59  
AA4 1 2  N VAL A 65  ? N VAL 1 67  O ARG B 64  ? O ARG 2 66  
AA5 1 2  N ASP A 75  ? N ASP 1 77  O TYR B 76  ? O TYR 2 78  
AA6 1 2  N ALA A 125 ? N ALA 1 127 O ASN B 126 ? O ASN 2 128 
AA7 1 2  N LYS A 132 ? N LYS 1 134 O LYS B 133 ? O LYS 2 135 
# 
_pdbx_entry_details.entry_id                   8UL1 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             O 
_pdbx_validate_rmsd_angle.auth_asym_id_1             2 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ALA 
_pdbx_validate_rmsd_angle.auth_seq_id_1              60 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             C 
_pdbx_validate_rmsd_angle.auth_asym_id_2             2 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ALA 
_pdbx_validate_rmsd_angle.auth_seq_id_2              60 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             N 
_pdbx_validate_rmsd_angle.auth_asym_id_3             2 
_pdbx_validate_rmsd_angle.auth_comp_id_3             PHE 
_pdbx_validate_rmsd_angle.auth_seq_id_3              61 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                132.81 
_pdbx_validate_rmsd_angle.angle_target_value         122.70 
_pdbx_validate_rmsd_angle.angle_deviation            10.11 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.60 
_pdbx_validate_rmsd_angle.linker_flag                Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASN 1 124 ? ? 82.52   14.51   
2 1 GLU 1 164 ? ? -39.38  130.00  
3 1 HIS 1 190 ? ? -172.17 -173.13 
4 1 LYS 2 182 ? ? -39.17  120.69  
# 
loop_
_pdbx_validate_polymer_linkage.id 
_pdbx_validate_polymer_linkage.PDB_model_num 
_pdbx_validate_polymer_linkage.auth_atom_id_1 
_pdbx_validate_polymer_linkage.auth_asym_id_1 
_pdbx_validate_polymer_linkage.auth_comp_id_1 
_pdbx_validate_polymer_linkage.auth_seq_id_1 
_pdbx_validate_polymer_linkage.PDB_ins_code_1 
_pdbx_validate_polymer_linkage.label_alt_id_1 
_pdbx_validate_polymer_linkage.auth_atom_id_2 
_pdbx_validate_polymer_linkage.auth_asym_id_2 
_pdbx_validate_polymer_linkage.auth_comp_id_2 
_pdbx_validate_polymer_linkage.auth_seq_id_2 
_pdbx_validate_polymer_linkage.PDB_ins_code_2 
_pdbx_validate_polymer_linkage.label_alt_id_2 
_pdbx_validate_polymer_linkage.dist 
1 1 C  1 PHE 61 ? ? N1 1 PIA 64 ? ? 1.03 
2 1 C3 1 PIA 64 ? ? N  1 ASN 65 ? ? 0.99 
3 1 C3 2 PIA 64 ? ? N  2 ASN 65 ? ? 1.67 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 1 MET 1   ? A MET 1   
2 1 Y 1 1 ASN 222 ? A ASN 220 
3 1 Y 1 2 MET 1   ? B MET 1   
4 1 Y 1 2 ASN 222 ? B ASN 220 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
GOL C1   C N N 137 
GOL O1   O N N 138 
GOL C2   C N N 139 
GOL O2   O N N 140 
GOL C3   C N N 141 
GOL O3   O N N 142 
GOL H11  H N N 143 
GOL H12  H N N 144 
GOL HO1  H N N 145 
GOL H2   H N N 146 
GOL HO2  H N N 147 
GOL H31  H N N 148 
GOL H32  H N N 149 
GOL HO3  H N N 150 
HIS N    N N N 151 
HIS CA   C N S 152 
HIS C    C N N 153 
HIS O    O N N 154 
HIS CB   C N N 155 
HIS CG   C Y N 156 
HIS ND1  N Y N 157 
HIS CD2  C Y N 158 
HIS CE1  C Y N 159 
HIS NE2  N Y N 160 
HIS OXT  O N N 161 
HIS H    H N N 162 
HIS H2   H N N 163 
HIS HA   H N N 164 
HIS HB2  H N N 165 
HIS HB3  H N N 166 
HIS HD1  H N N 167 
HIS HD2  H N N 168 
HIS HE1  H N N 169 
HIS HE2  H N N 170 
HIS HXT  H N N 171 
HOH O    O N N 172 
HOH H1   H N N 173 
HOH H2   H N N 174 
ILE N    N N N 175 
ILE CA   C N S 176 
ILE C    C N N 177 
ILE O    O N N 178 
ILE CB   C N S 179 
ILE CG1  C N N 180 
ILE CG2  C N N 181 
ILE CD1  C N N 182 
ILE OXT  O N N 183 
ILE H    H N N 184 
ILE H2   H N N 185 
ILE HA   H N N 186 
ILE HB   H N N 187 
ILE HG12 H N N 188 
ILE HG13 H N N 189 
ILE HG21 H N N 190 
ILE HG22 H N N 191 
ILE HG23 H N N 192 
ILE HD11 H N N 193 
ILE HD12 H N N 194 
ILE HD13 H N N 195 
ILE HXT  H N N 196 
LEU N    N N N 197 
LEU CA   C N S 198 
LEU C    C N N 199 
LEU O    O N N 200 
LEU CB   C N N 201 
LEU CG   C N N 202 
LEU CD1  C N N 203 
LEU CD2  C N N 204 
LEU OXT  O N N 205 
LEU H    H N N 206 
LEU H2   H N N 207 
LEU HA   H N N 208 
LEU HB2  H N N 209 
LEU HB3  H N N 210 
LEU HG   H N N 211 
LEU HD11 H N N 212 
LEU HD12 H N N 213 
LEU HD13 H N N 214 
LEU HD21 H N N 215 
LEU HD22 H N N 216 
LEU HD23 H N N 217 
LEU HXT  H N N 218 
LYS N    N N N 219 
LYS CA   C N S 220 
LYS C    C N N 221 
LYS O    O N N 222 
LYS CB   C N N 223 
LYS CG   C N N 224 
LYS CD   C N N 225 
LYS CE   C N N 226 
LYS NZ   N N N 227 
LYS OXT  O N N 228 
LYS H    H N N 229 
LYS H2   H N N 230 
LYS HA   H N N 231 
LYS HB2  H N N 232 
LYS HB3  H N N 233 
LYS HG2  H N N 234 
LYS HG3  H N N 235 
LYS HD2  H N N 236 
LYS HD3  H N N 237 
LYS HE2  H N N 238 
LYS HE3  H N N 239 
LYS HZ1  H N N 240 
LYS HZ2  H N N 241 
LYS HZ3  H N N 242 
LYS HXT  H N N 243 
MET N    N N N 244 
MET CA   C N S 245 
MET C    C N N 246 
MET O    O N N 247 
MET CB   C N N 248 
MET CG   C N N 249 
MET SD   S N N 250 
MET CE   C N N 251 
MET OXT  O N N 252 
MET H    H N N 253 
MET H2   H N N 254 
MET HA   H N N 255 
MET HB2  H N N 256 
MET HB3  H N N 257 
MET HG2  H N N 258 
MET HG3  H N N 259 
MET HE1  H N N 260 
MET HE2  H N N 261 
MET HE3  H N N 262 
MET HXT  H N N 263 
PHE N    N N N 264 
PHE CA   C N S 265 
PHE C    C N N 266 
PHE O    O N N 267 
PHE CB   C N N 268 
PHE CG   C Y N 269 
PHE CD1  C Y N 270 
PHE CD2  C Y N 271 
PHE CE1  C Y N 272 
PHE CE2  C Y N 273 
PHE CZ   C Y N 274 
PHE OXT  O N N 275 
PHE H    H N N 276 
PHE H2   H N N 277 
PHE HA   H N N 278 
PHE HB2  H N N 279 
PHE HB3  H N N 280 
PHE HD1  H N N 281 
PHE HD2  H N N 282 
PHE HE1  H N N 283 
PHE HE2  H N N 284 
PHE HZ   H N N 285 
PHE HXT  H N N 286 
PIA N1   N N N 287 
PIA CA1  C N S 288 
PIA CB1  C N N 289 
PIA C1   C N N 290 
PIA N2   N N N 291 
PIA N3   N N N 292 
PIA C2   C N N 293 
PIA O2   O N N 294 
PIA CA2  C N N 295 
PIA CA3  C N N 296 
PIA C3   C N N 297 
PIA O3   O N N 298 
PIA CB2  C N N 299 
PIA CG2  C Y N 300 
PIA CD1  C Y N 301 
PIA CD2  C Y N 302 
PIA CE1  C Y N 303 
PIA CE2  C Y N 304 
PIA CZ   C Y N 305 
PIA OH   O N N 306 
PIA OXT  O N N 307 
PIA H    H N N 308 
PIA H2   H N N 309 
PIA HA1  H N N 310 
PIA HB11 H N N 311 
PIA HB12 H N N 312 
PIA HB13 H N N 313 
PIA HA31 H N N 314 
PIA HA32 H N N 315 
PIA HB2  H N N 316 
PIA HD1  H N N 317 
PIA HD2  H N N 318 
PIA HE1  H N N 319 
PIA HE2  H N N 320 
PIA HH   H N N 321 
PIA HXT  H N N 322 
PRO N    N N N 323 
PRO CA   C N S 324 
PRO C    C N N 325 
PRO O    O N N 326 
PRO CB   C N N 327 
PRO CG   C N N 328 
PRO CD   C N N 329 
PRO OXT  O N N 330 
PRO H    H N N 331 
PRO HA   H N N 332 
PRO HB2  H N N 333 
PRO HB3  H N N 334 
PRO HG2  H N N 335 
PRO HG3  H N N 336 
PRO HD2  H N N 337 
PRO HD3  H N N 338 
PRO HXT  H N N 339 
SER N    N N N 340 
SER CA   C N S 341 
SER C    C N N 342 
SER O    O N N 343 
SER CB   C N N 344 
SER OG   O N N 345 
SER OXT  O N N 346 
SER H    H N N 347 
SER H2   H N N 348 
SER HA   H N N 349 
SER HB2  H N N 350 
SER HB3  H N N 351 
SER HG   H N N 352 
SER HXT  H N N 353 
SO4 S    S N N 354 
SO4 O1   O N N 355 
SO4 O2   O N N 356 
SO4 O3   O N N 357 
SO4 O4   O N N 358 
THR N    N N N 359 
THR CA   C N S 360 
THR C    C N N 361 
THR O    O N N 362 
THR CB   C N R 363 
THR OG1  O N N 364 
THR CG2  C N N 365 
THR OXT  O N N 366 
THR H    H N N 367 
THR H2   H N N 368 
THR HA   H N N 369 
THR HB   H N N 370 
THR HG1  H N N 371 
THR HG21 H N N 372 
THR HG22 H N N 373 
THR HG23 H N N 374 
THR HXT  H N N 375 
TRP N    N N N 376 
TRP CA   C N S 377 
TRP C    C N N 378 
TRP O    O N N 379 
TRP CB   C N N 380 
TRP CG   C Y N 381 
TRP CD1  C Y N 382 
TRP CD2  C Y N 383 
TRP NE1  N Y N 384 
TRP CE2  C Y N 385 
TRP CE3  C Y N 386 
TRP CZ2  C Y N 387 
TRP CZ3  C Y N 388 
TRP CH2  C Y N 389 
TRP OXT  O N N 390 
TRP H    H N N 391 
TRP H2   H N N 392 
TRP HA   H N N 393 
TRP HB2  H N N 394 
TRP HB3  H N N 395 
TRP HD1  H N N 396 
TRP HE1  H N N 397 
TRP HE3  H N N 398 
TRP HZ2  H N N 399 
TRP HZ3  H N N 400 
TRP HH2  H N N 401 
TRP HXT  H N N 402 
TYR N    N N N 403 
TYR CA   C N S 404 
TYR C    C N N 405 
TYR O    O N N 406 
TYR CB   C N N 407 
TYR CG   C Y N 408 
TYR CD1  C Y N 409 
TYR CD2  C Y N 410 
TYR CE1  C Y N 411 
TYR CE2  C Y N 412 
TYR CZ   C Y N 413 
TYR OH   O N N 414 
TYR OXT  O N N 415 
TYR H    H N N 416 
TYR H2   H N N 417 
TYR HA   H N N 418 
TYR HB2  H N N 419 
TYR HB3  H N N 420 
TYR HD1  H N N 421 
TYR HD2  H N N 422 
TYR HE1  H N N 423 
TYR HE2  H N N 424 
TYR HH   H N N 425 
TYR HXT  H N N 426 
VAL N    N N N 427 
VAL CA   C N S 428 
VAL C    C N N 429 
VAL O    O N N 430 
VAL CB   C N N 431 
VAL CG1  C N N 432 
VAL CG2  C N N 433 
VAL OXT  O N N 434 
VAL H    H N N 435 
VAL H2   H N N 436 
VAL HA   H N N 437 
VAL HB   H N N 438 
VAL HG11 H N N 439 
VAL HG12 H N N 440 
VAL HG13 H N N 441 
VAL HG21 H N N 442 
VAL HG22 H N N 443 
VAL HG23 H N N 444 
VAL HXT  H N N 445 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
GOL C1  O1   sing N N 129 
GOL C1  C2   sing N N 130 
GOL C1  H11  sing N N 131 
GOL C1  H12  sing N N 132 
GOL O1  HO1  sing N N 133 
GOL C2  O2   sing N N 134 
GOL C2  C3   sing N N 135 
GOL C2  H2   sing N N 136 
GOL O2  HO2  sing N N 137 
GOL C3  O3   sing N N 138 
GOL C3  H31  sing N N 139 
GOL C3  H32  sing N N 140 
GOL O3  HO3  sing N N 141 
HIS N   CA   sing N N 142 
HIS N   H    sing N N 143 
HIS N   H2   sing N N 144 
HIS CA  C    sing N N 145 
HIS CA  CB   sing N N 146 
HIS CA  HA   sing N N 147 
HIS C   O    doub N N 148 
HIS C   OXT  sing N N 149 
HIS CB  CG   sing N N 150 
HIS CB  HB2  sing N N 151 
HIS CB  HB3  sing N N 152 
HIS CG  ND1  sing Y N 153 
HIS CG  CD2  doub Y N 154 
HIS ND1 CE1  doub Y N 155 
HIS ND1 HD1  sing N N 156 
HIS CD2 NE2  sing Y N 157 
HIS CD2 HD2  sing N N 158 
HIS CE1 NE2  sing Y N 159 
HIS CE1 HE1  sing N N 160 
HIS NE2 HE2  sing N N 161 
HIS OXT HXT  sing N N 162 
HOH O   H1   sing N N 163 
HOH O   H2   sing N N 164 
ILE N   CA   sing N N 165 
ILE N   H    sing N N 166 
ILE N   H2   sing N N 167 
ILE CA  C    sing N N 168 
ILE CA  CB   sing N N 169 
ILE CA  HA   sing N N 170 
ILE C   O    doub N N 171 
ILE C   OXT  sing N N 172 
ILE CB  CG1  sing N N 173 
ILE CB  CG2  sing N N 174 
ILE CB  HB   sing N N 175 
ILE CG1 CD1  sing N N 176 
ILE CG1 HG12 sing N N 177 
ILE CG1 HG13 sing N N 178 
ILE CG2 HG21 sing N N 179 
ILE CG2 HG22 sing N N 180 
ILE CG2 HG23 sing N N 181 
ILE CD1 HD11 sing N N 182 
ILE CD1 HD12 sing N N 183 
ILE CD1 HD13 sing N N 184 
ILE OXT HXT  sing N N 185 
LEU N   CA   sing N N 186 
LEU N   H    sing N N 187 
LEU N   H2   sing N N 188 
LEU CA  C    sing N N 189 
LEU CA  CB   sing N N 190 
LEU CA  HA   sing N N 191 
LEU C   O    doub N N 192 
LEU C   OXT  sing N N 193 
LEU CB  CG   sing N N 194 
LEU CB  HB2  sing N N 195 
LEU CB  HB3  sing N N 196 
LEU CG  CD1  sing N N 197 
LEU CG  CD2  sing N N 198 
LEU CG  HG   sing N N 199 
LEU CD1 HD11 sing N N 200 
LEU CD1 HD12 sing N N 201 
LEU CD1 HD13 sing N N 202 
LEU CD2 HD21 sing N N 203 
LEU CD2 HD22 sing N N 204 
LEU CD2 HD23 sing N N 205 
LEU OXT HXT  sing N N 206 
LYS N   CA   sing N N 207 
LYS N   H    sing N N 208 
LYS N   H2   sing N N 209 
LYS CA  C    sing N N 210 
LYS CA  CB   sing N N 211 
LYS CA  HA   sing N N 212 
LYS C   O    doub N N 213 
LYS C   OXT  sing N N 214 
LYS CB  CG   sing N N 215 
LYS CB  HB2  sing N N 216 
LYS CB  HB3  sing N N 217 
LYS CG  CD   sing N N 218 
LYS CG  HG2  sing N N 219 
LYS CG  HG3  sing N N 220 
LYS CD  CE   sing N N 221 
LYS CD  HD2  sing N N 222 
LYS CD  HD3  sing N N 223 
LYS CE  NZ   sing N N 224 
LYS CE  HE2  sing N N 225 
LYS CE  HE3  sing N N 226 
LYS NZ  HZ1  sing N N 227 
LYS NZ  HZ2  sing N N 228 
LYS NZ  HZ3  sing N N 229 
LYS OXT HXT  sing N N 230 
MET N   CA   sing N N 231 
MET N   H    sing N N 232 
MET N   H2   sing N N 233 
MET CA  C    sing N N 234 
MET CA  CB   sing N N 235 
MET CA  HA   sing N N 236 
MET C   O    doub N N 237 
MET C   OXT  sing N N 238 
MET CB  CG   sing N N 239 
MET CB  HB2  sing N N 240 
MET CB  HB3  sing N N 241 
MET CG  SD   sing N N 242 
MET CG  HG2  sing N N 243 
MET CG  HG3  sing N N 244 
MET SD  CE   sing N N 245 
MET CE  HE1  sing N N 246 
MET CE  HE2  sing N N 247 
MET CE  HE3  sing N N 248 
MET OXT HXT  sing N N 249 
PHE N   CA   sing N N 250 
PHE N   H    sing N N 251 
PHE N   H2   sing N N 252 
PHE CA  C    sing N N 253 
PHE CA  CB   sing N N 254 
PHE CA  HA   sing N N 255 
PHE C   O    doub N N 256 
PHE C   OXT  sing N N 257 
PHE CB  CG   sing N N 258 
PHE CB  HB2  sing N N 259 
PHE CB  HB3  sing N N 260 
PHE CG  CD1  doub Y N 261 
PHE CG  CD2  sing Y N 262 
PHE CD1 CE1  sing Y N 263 
PHE CD1 HD1  sing N N 264 
PHE CD2 CE2  doub Y N 265 
PHE CD2 HD2  sing N N 266 
PHE CE1 CZ   doub Y N 267 
PHE CE1 HE1  sing N N 268 
PHE CE2 CZ   sing Y N 269 
PHE CE2 HE2  sing N N 270 
PHE CZ  HZ   sing N N 271 
PHE OXT HXT  sing N N 272 
PIA N1  CA1  sing N N 273 
PIA N1  H    sing N N 274 
PIA N1  H2   sing N N 275 
PIA CA1 CB1  sing N N 276 
PIA CA1 C1   sing N N 277 
PIA CA1 HA1  sing N N 278 
PIA CB1 HB11 sing N N 279 
PIA CB1 HB12 sing N N 280 
PIA CB1 HB13 sing N N 281 
PIA C1  N2   doub N N 282 
PIA C1  N3   sing N N 283 
PIA N2  CA2  sing N N 284 
PIA N3  C2   sing N N 285 
PIA N3  CA3  sing N N 286 
PIA C2  O2   doub N N 287 
PIA C2  CA2  sing N N 288 
PIA CA2 CB2  doub N Z 289 
PIA CA3 C3   sing N N 290 
PIA CA3 HA31 sing N N 291 
PIA CA3 HA32 sing N N 292 
PIA C3  O3   doub N N 293 
PIA C3  OXT  sing N N 294 
PIA CB2 CG2  sing N N 295 
PIA CB2 HB2  sing N N 296 
PIA CG2 CD1  doub Y N 297 
PIA CG2 CD2  sing Y N 298 
PIA CD1 CE1  sing Y N 299 
PIA CD1 HD1  sing N N 300 
PIA CD2 CE2  doub Y N 301 
PIA CD2 HD2  sing N N 302 
PIA CE1 CZ   doub Y N 303 
PIA CE1 HE1  sing N N 304 
PIA CE2 CZ   sing Y N 305 
PIA CE2 HE2  sing N N 306 
PIA CZ  OH   sing N N 307 
PIA OH  HH   sing N N 308 
PIA OXT HXT  sing N N 309 
PRO N   CA   sing N N 310 
PRO N   CD   sing N N 311 
PRO N   H    sing N N 312 
PRO CA  C    sing N N 313 
PRO CA  CB   sing N N 314 
PRO CA  HA   sing N N 315 
PRO C   O    doub N N 316 
PRO C   OXT  sing N N 317 
PRO CB  CG   sing N N 318 
PRO CB  HB2  sing N N 319 
PRO CB  HB3  sing N N 320 
PRO CG  CD   sing N N 321 
PRO CG  HG2  sing N N 322 
PRO CG  HG3  sing N N 323 
PRO CD  HD2  sing N N 324 
PRO CD  HD3  sing N N 325 
PRO OXT HXT  sing N N 326 
SER N   CA   sing N N 327 
SER N   H    sing N N 328 
SER N   H2   sing N N 329 
SER CA  C    sing N N 330 
SER CA  CB   sing N N 331 
SER CA  HA   sing N N 332 
SER C   O    doub N N 333 
SER C   OXT  sing N N 334 
SER CB  OG   sing N N 335 
SER CB  HB2  sing N N 336 
SER CB  HB3  sing N N 337 
SER OG  HG   sing N N 338 
SER OXT HXT  sing N N 339 
SO4 S   O1   doub N N 340 
SO4 S   O2   doub N N 341 
SO4 S   O3   sing N N 342 
SO4 S   O4   sing N N 343 
THR N   CA   sing N N 344 
THR N   H    sing N N 345 
THR N   H2   sing N N 346 
THR CA  C    sing N N 347 
THR CA  CB   sing N N 348 
THR CA  HA   sing N N 349 
THR C   O    doub N N 350 
THR C   OXT  sing N N 351 
THR CB  OG1  sing N N 352 
THR CB  CG2  sing N N 353 
THR CB  HB   sing N N 354 
THR OG1 HG1  sing N N 355 
THR CG2 HG21 sing N N 356 
THR CG2 HG22 sing N N 357 
THR CG2 HG23 sing N N 358 
THR OXT HXT  sing N N 359 
TRP N   CA   sing N N 360 
TRP N   H    sing N N 361 
TRP N   H2   sing N N 362 
TRP CA  C    sing N N 363 
TRP CA  CB   sing N N 364 
TRP CA  HA   sing N N 365 
TRP C   O    doub N N 366 
TRP C   OXT  sing N N 367 
TRP CB  CG   sing N N 368 
TRP CB  HB2  sing N N 369 
TRP CB  HB3  sing N N 370 
TRP CG  CD1  doub Y N 371 
TRP CG  CD2  sing Y N 372 
TRP CD1 NE1  sing Y N 373 
TRP CD1 HD1  sing N N 374 
TRP CD2 CE2  doub Y N 375 
TRP CD2 CE3  sing Y N 376 
TRP NE1 CE2  sing Y N 377 
TRP NE1 HE1  sing N N 378 
TRP CE2 CZ2  sing Y N 379 
TRP CE3 CZ3  doub Y N 380 
TRP CE3 HE3  sing N N 381 
TRP CZ2 CH2  doub Y N 382 
TRP CZ2 HZ2  sing N N 383 
TRP CZ3 CH2  sing Y N 384 
TRP CZ3 HZ3  sing N N 385 
TRP CH2 HH2  sing N N 386 
TRP OXT HXT  sing N N 387 
TYR N   CA   sing N N 388 
TYR N   H    sing N N 389 
TYR N   H2   sing N N 390 
TYR CA  C    sing N N 391 
TYR CA  CB   sing N N 392 
TYR CA  HA   sing N N 393 
TYR C   O    doub N N 394 
TYR C   OXT  sing N N 395 
TYR CB  CG   sing N N 396 
TYR CB  HB2  sing N N 397 
TYR CB  HB3  sing N N 398 
TYR CG  CD1  doub Y N 399 
TYR CG  CD2  sing Y N 400 
TYR CD1 CE1  sing Y N 401 
TYR CD1 HD1  sing N N 402 
TYR CD2 CE2  doub Y N 403 
TYR CD2 HD2  sing N N 404 
TYR CE1 CZ   doub Y N 405 
TYR CE1 HE1  sing N N 406 
TYR CE2 CZ   sing Y N 407 
TYR CE2 HE2  sing N N 408 
TYR CZ  OH   sing N N 409 
TYR OH  HH   sing N N 410 
TYR OXT HXT  sing N N 411 
VAL N   CA   sing N N 412 
VAL N   H    sing N N 413 
VAL N   H2   sing N N 414 
VAL CA  C    sing N N 415 
VAL CA  CB   sing N N 416 
VAL CA  HA   sing N N 417 
VAL C   O    doub N N 418 
VAL C   OXT  sing N N 419 
VAL CB  CG1  sing N N 420 
VAL CB  CG2  sing N N 421 
VAL CB  HB   sing N N 422 
VAL CG1 HG11 sing N N 423 
VAL CG1 HG12 sing N N 424 
VAL CG1 HG13 sing N N 425 
VAL CG2 HG21 sing N N 426 
VAL CG2 HG22 sing N N 427 
VAL CG2 HG23 sing N N 428 
VAL OXT HXT  sing N N 429 
# 
_pdbx_audit_support.funding_organization   'Biotechnology and Biological Sciences Research Council (BBSRC)' 
_pdbx_audit_support.country                'United Kingdom' 
_pdbx_audit_support.grant_number           BB/P00752X/1 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7QLJ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    8UL1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.025253 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013423 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012674 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.pdbx_scat_Z 
_atom_type.pdbx_N_electrons 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
C 6  6  2.310  20.844 1.020 10.208 1.589 0.569  0.865 51.651 0.216   
H 1  1  0.493  10.511 0.323 26.126 0.140 3.142  0.041 57.800 0.003   
N 7  7  12.222 0.006  3.135 9.893  2.014 28.997 1.167 0.583  -11.538 
O 8  8  3.049  13.277 2.287 5.701  1.546 0.324  0.867 32.909 0.251   
S 16 16 6.905  1.468  5.203 22.215 1.438 0.254  1.586 56.172 0.867   
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
_atom_site.calc_flag 
ATOM   1    N N   . SER A 1 2   ? -21.968 4.853   -36.608 0.330 57.650  0 2   SER 1 N   1 ? 
ATOM   2    C CA  . SER A 1 2   ? -21.064 5.117   -35.447 0.330 56.660  0 2   SER 1 CA  1 ? 
ATOM   3    C C   . SER A 1 2   ? -21.826 5.886   -34.356 0.330 53.480  0 2   SER 1 C   1 ? 
ATOM   4    O O   . SER A 1 2   ? -22.289 7.014   -34.630 0.330 52.730  0 2   SER 1 O   1 ? 
ATOM   5    C CB  . SER A 1 2   ? -19.820 5.863   -35.893 0.330 58.330  0 2   SER 1 CB  1 ? 
ATOM   6    O OG  . SER A 1 2   ? -18.784 5.778   -34.922 0.330 57.470  0 2   SER 1 OG  1 ? 
ATOM   7    N N   . ALA A 1 3   ? -21.967 5.288   -33.168 0.330 50.410  0 3   ALA 1 N   1 ? 
ATOM   8    C CA  . ALA A 1 3   ? -22.539 5.934   -31.962 0.330 48.640  0 3   ALA 1 CA  1 ? 
ATOM   9    C C   . ALA A 1 3   ? -21.653 7.124   -31.574 0.330 46.440  0 3   ALA 1 C   1 ? 
ATOM   10   O O   . ALA A 1 3   ? -22.193 8.142   -31.093 0.330 50.230  0 3   ALA 1 O   1 ? 
ATOM   11   C CB  . ALA A 1 3   ? -22.638 4.928   -30.842 0.330 48.900  0 3   ALA 1 CB  1 ? 
ATOM   12   N N   . ILE A 1 4   ? -20.347 6.998   -31.825 0.330 42.010  0 4   ILE 1 N   1 ? 
ATOM   13   C CA  . ILE A 1 4   ? -19.286 7.961   -31.410 0.330 40.280  0 4   ILE 1 CA  1 ? 
ATOM   14   C C   . ILE A 1 4   ? -19.103 9.039   -32.483 0.330 39.200  0 4   ILE 1 C   1 ? 
ATOM   15   O O   . ILE A 1 4   ? -18.852 8.692   -33.644 0.330 39.710  0 4   ILE 1 O   1 ? 
ATOM   16   C CB  . ILE A 1 4   ? -17.977 7.205   -31.131 0.330 38.620  0 4   ILE 1 CB  1 ? 
ATOM   17   C CG1 . ILE A 1 4   ? -18.167 6.190   -30.000 0.330 38.800  0 4   ILE 1 CG1 1 ? 
ATOM   18   C CG2 . ILE A 1 4   ? -16.854 8.182   -30.844 0.330 38.210  0 4   ILE 1 CG2 1 ? 
ATOM   19   C CD1 . ILE A 1 4   ? -16.919 5.446   -29.630 0.330 38.430  0 4   ILE 1 CD1 1 ? 
ATOM   20   N N   . LYS A 1 5   ? -19.203 10.307  -32.083 0.330 38.670  0 5   LYS 1 N   1 ? 
ATOM   21   C CA  . LYS A 1 5   ? -19.053 11.483  -32.973 0.330 39.100  0 5   LYS 1 CA  1 ? 
ATOM   22   C C   . LYS A 1 5   ? -17.587 11.904  -32.981 0.330 36.610  0 5   LYS 1 C   1 ? 
ATOM   23   O O   . LYS A 1 5   ? -16.831 11.520  -32.096 0.330 34.460  0 5   LYS 1 O   1 ? 
ATOM   24   C CB  . LYS A 1 5   ? -19.941 12.624  -32.476 0.330 41.950  0 5   LYS 1 CB  1 ? 
ATOM   25   C CG  . LYS A 1 5   ? -21.276 12.194  -31.880 0.330 46.360  0 5   LYS 1 CG  1 ? 
ATOM   26   C CD  . LYS A 1 5   ? -22.295 11.762  -32.906 0.330 48.700  0 5   LYS 1 CD  1 ? 
ATOM   27   C CE  . LYS A 1 5   ? -22.221 10.285  -33.242 0.330 49.610  0 5   LYS 1 CE  1 ? 
ATOM   28   N NZ  . LYS A 1 5   ? -23.100 9.931   -34.387 0.330 48.780  0 5   LYS 1 NZ  1 ? 
ATOM   29   N N   . PRO A 1 6   ? -17.153 12.719  -33.966 0.330 35.010  0 6   PRO 1 N   1 ? 
ATOM   30   C CA  . PRO A 1 6   ? -15.771 13.197  -34.033 0.330 34.160  0 6   PRO 1 CA  1 ? 
ATOM   31   C C   . PRO A 1 6   ? -15.381 14.094  -32.849 0.330 33.000  0 6   PRO 1 C   1 ? 
ATOM   32   O O   . PRO A 1 6   ? -14.203 14.198  -32.564 0.330 32.400  0 6   PRO 1 O   1 ? 
ATOM   33   C CB  . PRO A 1 6   ? -15.715 14.012  -35.333 0.330 35.070  0 6   PRO 1 CB  1 ? 
ATOM   34   C CG  . PRO A 1 6   ? -16.912 13.539  -36.127 0.330 35.830  0 6   PRO 1 CG  1 ? 
ATOM   35   C CD  . PRO A 1 6   ? -17.964 13.187  -35.099 0.330 36.290  0 6   PRO 1 CD  1 ? 
ATOM   36   N N   . ASP A 1 7   ? -16.374 14.714  -32.201 0.330 32.440  0 7   ASP 1 N   1 ? 
ATOM   37   C CA  . ASP A 1 7   ? -16.196 15.623  -31.037 0.330 31.780  0 7   ASP 1 CA  1 ? 
ATOM   38   C C   . ASP A 1 7   ? -17.114 15.169  -29.901 0.330 31.290  0 7   ASP 1 C   1 ? 
ATOM   39   O O   . ASP A 1 7   ? -18.330 15.344  -30.032 0.330 31.040  0 7   ASP 1 O   1 ? 
ATOM   40   C CB  . ASP A 1 7   ? -16.482 17.075  -31.417 0.330 33.030  0 7   ASP 1 CB  1 ? 
ATOM   41   C CG  . ASP A 1 7   ? -15.588 17.552  -32.546 0.330 34.470  0 7   ASP 1 CG  1 ? 
ATOM   42   O OD1 . ASP A 1 7   ? -14.356 17.548  -32.356 0.330 34.160  0 7   ASP 1 OD1 1 ? 
ATOM   43   O OD2 . ASP A 1 7   ? -16.128 17.877  -33.612 0.330 35.940  0 7   ASP 1 OD2 1 ? 
ATOM   44   N N   . MET A 1 8   ? -16.539 14.607  -28.836 0.330 28.750  0 8   MET 1 N   1 ? 
ATOM   45   C CA  . MET A 1 8   ? -17.283 14.077  -27.670 0.330 28.720  0 8   MET 1 CA  1 ? 
ATOM   46   C C   . MET A 1 8   ? -16.885 14.882  -26.430 0.330 27.700  0 8   MET 1 C   1 ? 
ATOM   47   O O   . MET A 1 8   ? -15.681 15.171  -26.264 0.330 28.030  0 8   MET 1 O   1 ? 
ATOM   48   C CB  . MET A 1 8   ? -16.973 12.596  -27.423 0.330 30.140  0 8   MET 1 CB  1 ? 
ATOM   49   C CG  . MET A 1 8   ? -17.155 11.685  -28.641 0.330 32.040  0 8   MET 1 CG  1 ? 
ATOM   50   S SD  . MET A 1 8   ? -18.862 11.151  -28.954 0.330 32.690  0 8   MET 1 SD  1 ? 
ATOM   51   C CE  . MET A 1 8   ? -19.292 10.312  -27.431 0.330 30.470  0 8   MET 1 CE  1 ? 
ATOM   52   N N   . LYS A 1 9   ? -17.860 15.196  -25.580 0.330 27.300  0 9   LYS 1 N   1 ? 
ATOM   53   C CA  . LYS A 1 9   ? -17.632 15.869  -24.277 0.330 26.230  0 9   LYS 1 CA  1 ? 
ATOM   54   C C   . LYS A 1 9   ? -17.267 14.809  -23.243 0.330 25.230  0 9   LYS 1 C   1 ? 
ATOM   55   O O   . LYS A 1 9   ? -17.610 13.632  -23.454 0.330 23.550  0 9   LYS 1 O   1 ? 
ATOM   56   C CB  . LYS A 1 9   ? -18.873 16.655  -23.852 0.330 28.030  0 9   LYS 1 CB  1 ? 
ATOM   57   C CG  . LYS A 1 9   ? -19.280 17.755  -24.815 0.330 29.240  0 9   LYS 1 CG  1 ? 
ATOM   58   C CD  . LYS A 1 9   ? -20.339 18.684  -24.262 0.330 31.650  0 9   LYS 1 CD  1 ? 
ATOM   59   C CE  . LYS A 1 9   ? -20.705 19.785  -25.241 0.330 33.110  0 9   LYS 1 CE  1 ? 
ATOM   60   N NZ  . LYS A 1 9   ? -21.859 20.589  -24.774 0.330 32.450  0 9   LYS 1 NZ  1 ? 
ATOM   61   N N   . ILE A 1 10  ? -16.607 15.229  -22.165 0.330 24.650  0 10  ILE 1 N   1 ? 
ATOM   62   C CA  . ILE A 1 10  ? -16.148 14.338  -21.065 0.330 24.530  0 10  ILE 1 CA  1 ? 
ATOM   63   C C   . ILE A 1 10  ? -16.660 14.918  -19.744 0.330 24.590  0 10  ILE 1 C   1 ? 
ATOM   64   O O   . ILE A 1 10  ? -16.420 16.118  -19.499 0.330 24.050  0 10  ILE 1 O   1 ? 
ATOM   65   C CB  . ILE A 1 10  ? -14.611 14.208  -21.079 0.330 24.790  0 10  ILE 1 CB  1 ? 
ATOM   66   C CG1 . ILE A 1 10  ? -14.078 13.737  -22.433 0.330 25.770  0 10  ILE 1 CG1 1 ? 
ATOM   67   C CG2 . ILE A 1 10  ? -14.140 13.295  -19.960 0.330 24.880  0 10  ILE 1 CG2 1 ? 
ATOM   68   C CD1 . ILE A 1 10  ? -12.602 14.057  -22.645 0.330 26.440  0 10  ILE 1 CD1 1 ? 
ATOM   69   N N   . LYS A 1 11  ? -17.331 14.088  -18.939 0.330 24.350  0 11  LYS 1 N   1 ? 
ATOM   70   C CA  . LYS A 1 11  ? -17.725 14.396  -17.540 0.330 25.420  0 11  LYS 1 CA  1 ? 
ATOM   71   C C   . LYS A 1 11  ? -17.121 13.323  -16.641 0.330 25.020  0 11  LYS 1 C   1 ? 
ATOM   72   O O   . LYS A 1 11  ? -17.131 12.152  -17.042 0.330 23.930  0 11  LYS 1 O   1 ? 
ATOM   73   C CB  . LYS A 1 11  ? -19.244 14.427  -17.369 0.330 26.490  0 11  LYS 1 CB  1 ? 
ATOM   74   C CG  . LYS A 1 11  ? -19.960 15.487  -18.191 0.330 28.850  0 11  LYS 1 CG  1 ? 
ATOM   75   C CD  . LYS A 1 11  ? -19.630 16.879  -17.777 0.330 31.410  0 11  LYS 1 CD  1 ? 
ATOM   76   C CE  . LYS A 1 11  ? -20.320 17.909  -18.645 0.330 35.310  0 11  LYS 1 CE  1 ? 
ATOM   77   N NZ  . LYS A 1 11  ? -19.915 19.278  -18.256 0.330 38.630  0 11  LYS 1 NZ  1 ? 
ATOM   78   N N   . LEU A 1 12  ? -16.628 13.722  -15.469 0.330 25.680  0 12  LEU 1 N   1 ? 
ATOM   79   C CA  . LEU A 1 12  ? -15.723 12.888  -14.653 0.330 25.960  0 12  LEU 1 CA  1 ? 
ATOM   80   C C   . LEU A 1 12  ? -15.838 13.286  -13.177 0.330 24.300  0 12  LEU 1 C   1 ? 
ATOM   81   O O   . LEU A 1 12  ? -15.748 14.487  -12.864 0.330 23.530  0 12  LEU 1 O   1 ? 
ATOM   82   C CB  . LEU A 1 12  ? -14.311 13.110  -15.199 0.330 28.680  0 12  LEU 1 CB  1 ? 
ATOM   83   C CG  . LEU A 1 12  ? -13.225 12.208  -14.631 0.330 32.760  0 12  LEU 1 CG  1 ? 
ATOM   84   C CD1 . LEU A 1 12  ? -12.123 11.994  -15.665 0.330 34.300  0 12  LEU 1 CD1 1 ? 
ATOM   85   C CD2 . LEU A 1 12  ? -12.667 12.792  -13.336 0.330 32.050  0 12  LEU 1 CD2 1 ? 
ATOM   86   N N   . ARG A 1 13  ? -16.019 12.299  -12.304 0.330 23.220  0 13  ARG 1 N   1 ? 
ATOM   87   C CA  . ARG A 1 13  ? -15.864 12.474  -10.842 0.330 24.710  0 13  ARG 1 CA  1 ? 
ATOM   88   C C   . ARG A 1 13  ? -14.977 11.346  -10.327 0.330 23.740  0 13  ARG 1 C   1 ? 
ATOM   89   O O   . ARG A 1 13  ? -15.276 10.169  -10.617 0.330 23.470  0 13  ARG 1 O   1 ? 
ATOM   90   C CB  . ARG A 1 13  ? -17.209 12.494  -10.108 0.330 26.960  0 13  ARG 1 CB  1 ? 
ATOM   91   C CG  . ARG A 1 13  ? -17.049 12.406  -8.597  0.330 29.540  0 13  ARG 1 CG  1 ? 
ATOM   92   C CD  . ARG A 1 13  ? -18.209 12.990  -7.829  0.330 33.540  0 13  ARG 1 CD  1 ? 
ATOM   93   N NE  . ARG A 1 13  ? -18.234 14.439  -7.943  0.330 36.180  0 13  ARG 1 NE  1 ? 
ATOM   94   C CZ  . ARG A 1 13  ? -18.924 15.236  -7.139  0.330 38.190  0 13  ARG 1 CZ  1 ? 
ATOM   95   N NH1 . ARG A 1 13  ? -18.893 16.542  -7.325  0.330 38.960  0 13  ARG 1 NH1 1 ? 
ATOM   96   N NH2 . ARG A 1 13  ? -19.622 14.719  -6.142  0.330 39.420  0 13  ARG 1 NH2 1 ? 
ATOM   97   N N   . MET A 1 14  ? -13.890 11.713  -9.656  0.330 23.420  0 14  MET 1 N   1 ? 
ATOM   98   C CA  . MET A 1 14  ? -12.956 10.775  -8.987  0.330 23.150  0 14  MET 1 CA  1 ? 
ATOM   99   C C   . MET A 1 14  ? -13.108 10.960  -7.478  0.330 23.910  0 14  MET 1 C   1 ? 
ATOM   100  O O   . MET A 1 14  ? -13.012 12.121  -7.010  0.330 23.330  0 14  MET 1 O   1 ? 
ATOM   101  C CB  . MET A 1 14  ? -11.496 11.039  -9.373  0.330 23.550  0 14  MET 1 CB  1 ? 
ATOM   102  C CG  . MET A 1 14  ? -10.511 10.231  -8.544  0.330 23.300  0 14  MET 1 CG  1 ? 
ATOM   103  S SD  . MET A 1 14  ? -8.782  10.686  -8.802  0.330 25.000  0 14  MET 1 SD  1 ? 
ATOM   104  C CE  . MET A 1 14  ? -8.408  9.820   -10.324 0.330 24.730  0 14  MET 1 CE  1 ? 
ATOM   105  N N   . GLU A 1 15  ? -13.386 9.867   -6.768  0.330 23.560  0 15  GLU 1 N   1 ? 
ATOM   106  C CA  . GLU A 1 15  ? -13.290 9.798   -5.287  0.330 24.210  0 15  GLU 1 CA  1 ? 
ATOM   107  C C   . GLU A 1 15  ? -12.130 8.862   -4.959  0.330 23.210  0 15  GLU 1 C   1 ? 
ATOM   108  O O   . GLU A 1 15  ? -12.055 7.769   -5.574  0.330 22.750  0 15  GLU 1 O   1 ? 
ATOM   109  C CB  . GLU A 1 15  ? -14.606 9.323   -4.674  0.330 25.190  0 15  GLU 1 CB  1 ? 
ATOM   110  C CG  . GLU A 1 15  ? -15.811 10.000  -5.289  0.330 27.420  0 15  GLU 1 CG  1 ? 
ATOM   111  C CD  . GLU A 1 15  ? -17.093 9.949   -4.475  0.330 28.970  0 15  GLU 1 CD  1 ? 
ATOM   112  O OE1 . GLU A 1 15  ? -17.405 8.863   -3.901  0.330 29.390  0 15  GLU 1 OE1 1 ? 
ATOM   113  O OE2 . GLU A 1 15  ? -17.779 10.995  -4.434  0.330 29.170  0 15  GLU 1 OE2 1 ? 
ATOM   114  N N   . GLY A 1 16  ? -11.246 9.281   -4.059  0.330 21.730  0 16  GLY 1 N   1 ? 
ATOM   115  C CA  . GLY A 1 16  ? -9.980  8.565   -3.817  0.330 23.560  0 16  GLY 1 CA  1 ? 
ATOM   116  C C   . GLY A 1 16  ? -9.452  8.735   -2.410  0.330 22.300  0 16  GLY 1 C   1 ? 
ATOM   117  O O   . GLY A 1 16  ? -9.925  9.618   -1.667  0.330 21.190  0 16  GLY 1 O   1 ? 
ATOM   118  N N   . ASN A 1 17  ? -8.477  7.909   -2.059  0.330 23.380  0 17  ASN 1 N   1 ? 
ATOM   119  C CA  . ASN A 1 17  ? -7.714  8.063   -0.803  0.330 24.610  0 17  ASN 1 CA  1 ? 
ATOM   120  C C   . ASN A 1 17  ? -6.282  7.584   -1.039  0.330 24.560  0 17  ASN 1 C   1 ? 
ATOM   121  O O   . ASN A 1 17  ? -6.100  6.395   -1.383  0.330 24.500  0 17  ASN 1 O   1 ? 
ATOM   122  C CB  . ASN A 1 17  ? -8.393  7.324   0.350   0.330 26.310  0 17  ASN 1 CB  1 ? 
ATOM   123  C CG  . ASN A 1 17  ? -7.652  7.581   1.641   0.330 28.430  0 17  ASN 1 CG  1 ? 
ATOM   124  O OD1 . ASN A 1 17  ? -6.436  7.395   1.702   0.330 29.770  0 17  ASN 1 OD1 1 ? 
ATOM   125  N ND2 . ASN A 1 17  ? -8.361  8.059   2.649   0.330 32.310  0 17  ASN 1 ND2 1 ? 
ATOM   126  N N   . VAL A 1 18  ? -5.311  8.474   -0.833  0.330 24.320  0 18  VAL 1 N   1 ? 
ATOM   127  C CA  . VAL A 1 18  ? -3.858  8.154   -0.904  0.330 24.330  0 18  VAL 1 CA  1 ? 
ATOM   128  C C   . VAL A 1 18  ? -3.263  8.323   0.496   0.330 24.330  0 18  VAL 1 C   1 ? 
ATOM   129  O O   . VAL A 1 18  ? -3.383  9.424   1.068   0.330 23.970  0 18  VAL 1 O   1 ? 
ATOM   130  C CB  . VAL A 1 18  ? -3.141  9.027   -1.947  0.330 25.430  0 18  VAL 1 CB  1 ? 
ATOM   131  C CG1 . VAL A 1 18  ? -1.627  8.892   -1.866  0.330 26.710  0 18  VAL 1 CG1 1 ? 
ATOM   132  C CG2 . VAL A 1 18  ? -3.632  8.719   -3.348  0.330 25.540  0 18  VAL 1 CG2 1 ? 
ATOM   133  N N   . ASN A 1 19  ? -2.683  7.246   1.032   0.330 24.280  0 19  ASN 1 N   1 ? 
ATOM   134  C CA  . ASN A 1 19  ? -2.023  7.230   2.360   0.330 25.070  0 19  ASN 1 CA  1 ? 
ATOM   135  C C   . ASN A 1 19  ? -2.981  7.806   3.407   0.330 25.250  0 19  ASN 1 C   1 ? 
ATOM   136  O O   . ASN A 1 19  ? -2.506  8.530   4.287   0.330 25.420  0 19  ASN 1 O   1 ? 
ATOM   137  C CB  . ASN A 1 19  ? -0.701  7.999   2.328   0.330 25.820  0 19  ASN 1 CB  1 ? 
ATOM   138  C CG  . ASN A 1 19  ? 0.476   7.134   1.926   0.330 26.310  0 19  ASN 1 CG  1 ? 
ATOM   139  O OD1 . ASN A 1 19  ? 0.309   6.093   1.288   0.330 24.730  0 19  ASN 1 OD1 1 ? 
ATOM   140  N ND2 . ASN A 1 19  ? 1.671   7.554   2.307   0.330 25.580  0 19  ASN 1 ND2 1 ? 
ATOM   141  N N   . GLY A 1 20  ? -4.280  7.510   3.298   0.330 24.410  0 20  GLY 1 N   1 ? 
ATOM   142  C CA  . GLY A 1 20  ? -5.297  7.952   4.272   0.330 25.220  0 20  GLY 1 CA  1 ? 
ATOM   143  C C   . GLY A 1 20  ? -6.059  9.188   3.817   0.330 25.540  0 20  GLY 1 C   1 ? 
ATOM   144  O O   . GLY A 1 20  ? -7.246  9.308   4.184   0.330 26.490  0 20  GLY 1 O   1 ? 
ATOM   145  N N   . HIS A 1 21  ? -5.418  10.074  3.043   0.330 25.820  0 21  HIS 1 N   1 ? 
ATOM   146  C CA  . HIS A 1 21  ? -5.975  11.388  2.630   0.330 26.340  0 21  HIS 1 CA  1 ? 
ATOM   147  C C   . HIS A 1 21  ? -7.139  11.167  1.658   0.330 25.420  0 21  HIS 1 C   1 ? 
ATOM   148  O O   . HIS A 1 21  ? -6.927  10.534  0.608   0.330 26.600  0 21  HIS 1 O   1 ? 
ATOM   149  C CB  . HIS A 1 21  ? -4.861  12.276  2.058   0.330 28.770  0 21  HIS 1 CB  1 ? 
ATOM   150  C CG  . HIS A 1 21  ? -3.654  12.377  2.935   0.330 31.600  0 21  HIS 1 CG  1 ? 
ATOM   151  N ND1 . HIS A 1 21  ? -3.574  13.286  3.978   0.330 33.620  0 21  HIS 1 ND1 1 ? 
ATOM   152  C CD2 . HIS A 1 21  ? -2.477  11.709  2.926   0.330 33.980  0 21  HIS 1 CD2 1 ? 
ATOM   153  C CE1 . HIS A 1 21  ? -2.398  13.173  4.566   0.330 35.300  0 21  HIS 1 CE1 1 ? 
ATOM   154  N NE2 . HIS A 1 21  ? -1.708  12.202  3.947   0.330 34.580  0 21  HIS 1 NE2 1 ? 
ATOM   155  N N   . HIS A 1 22  ? -8.325  11.669  2.004   0.330 25.060  0 22  HIS 1 N   1 ? 
ATOM   156  C CA  . HIS A 1 22  ? -9.571  11.582  1.197   0.330 25.840  0 22  HIS 1 CA  1 ? 
ATOM   157  C C   . HIS A 1 22  ? -9.666  12.812  0.294   0.330 25.030  0 22  HIS 1 C   1 ? 
ATOM   158  O O   . HIS A 1 22  ? -9.304  13.919  0.746   0.330 23.500  0 22  HIS 1 O   1 ? 
ATOM   159  C CB  . HIS A 1 22  ? -10.809 11.468  2.108   0.330 29.110  0 22  HIS 1 CB  1 ? 
ATOM   160  C CG  . HIS A 1 22  ? -12.108 11.612  1.384   0.330 31.090  0 22  HIS 1 CG  1 ? 
ATOM   161  N ND1 . HIS A 1 22  ? -12.658 10.580  0.630   0.330 34.300  0 22  HIS 1 ND1 1 ? 
ATOM   162  C CD2 . HIS A 1 22  ? -12.966 12.653  1.286   0.330 33.810  0 22  HIS 1 CD2 1 ? 
ATOM   163  C CE1 . HIS A 1 22  ? -13.793 10.989  0.092   0.330 34.150  0 22  HIS 1 CE1 1 ? 
ATOM   164  N NE2 . HIS A 1 22  ? -14.012 12.254  0.493   0.330 34.130  0 22  HIS 1 NE2 1 ? 
ATOM   165  N N   . PHE A 1 23  ? -10.142 12.629  -0.936  0.330 22.670  0 23  PHE 1 N   1 ? 
ATOM   166  C CA  . PHE A 1 23  ? -10.309 13.742  -1.901  0.330 23.080  0 23  PHE 1 CA  1 ? 
ATOM   167  C C   . PHE A 1 23  ? -11.389 13.394  -2.916  0.330 21.850  0 23  PHE 1 C   1 ? 
ATOM   168  O O   . PHE A 1 23  ? -11.669 12.188  -3.145  0.330 21.860  0 23  PHE 1 O   1 ? 
ATOM   169  C CB  . PHE A 1 23  ? -8.985  14.059  -2.593  0.330 22.880  0 23  PHE 1 CB  1 ? 
ATOM   170  C CG  . PHE A 1 23  ? -8.415  12.888  -3.348  0.330 23.230  0 23  PHE 1 CG  1 ? 
ATOM   171  C CD1 . PHE A 1 23  ? -8.763  12.668  -4.672  0.330 24.330  0 23  PHE 1 CD1 1 ? 
ATOM   172  C CD2 . PHE A 1 23  ? -7.560  11.997  -2.728  0.330 23.100  0 23  PHE 1 CD2 1 ? 
ATOM   173  C CE1 . PHE A 1 23  ? -8.248  11.581  -5.361  0.330 24.330  0 23  PHE 1 CE1 1 ? 
ATOM   174  C CE2 . PHE A 1 23  ? -7.044  10.912  -3.418  0.330 23.970  0 23  PHE 1 CE2 1 ? 
ATOM   175  C CZ  . PHE A 1 23  ? -7.394  10.705  -4.732  0.330 23.910  0 23  PHE 1 CZ  1 ? 
ATOM   176  N N   . VAL A 1 24  ? -11.977 14.446  -3.494  0.330 21.360  0 24  VAL 1 N   1 ? 
ATOM   177  C CA  . VAL A 1 24  ? -12.996 14.377  -4.574  0.330 20.900  0 24  VAL 1 CA  1 ? 
ATOM   178  C C   . VAL A 1 24  ? -12.598 15.395  -5.642  0.330 21.920  0 24  VAL 1 C   1 ? 
ATOM   179  O O   . VAL A 1 24  ? -12.395 16.582  -5.287  0.330 20.700  0 24  VAL 1 O   1 ? 
ATOM   180  C CB  . VAL A 1 24  ? -14.420 14.647  -4.049  0.330 21.610  0 24  VAL 1 CB  1 ? 
ATOM   181  C CG1 . VAL A 1 24  ? -15.427 14.663  -5.186  0.330 23.030  0 24  VAL 1 CG1 1 ? 
ATOM   182  C CG2 . VAL A 1 24  ? -14.835 13.651  -2.970  0.330 21.670  0 24  VAL 1 CG2 1 ? 
ATOM   183  N N   . ILE A 1 25  ? -12.483 14.941  -6.892  0.330 21.000  0 25  ILE 1 N   1 ? 
ATOM   184  C CA  . ILE A 1 25  ? -12.049 15.787  -8.041  0.330 22.200  0 25  ILE 1 CA  1 ? 
ATOM   185  C C   . ILE A 1 25  ? -13.072 15.633  -9.170  0.330 21.910  0 25  ILE 1 C   1 ? 
ATOM   186  O O   . ILE A 1 25  ? -13.391 14.481  -9.517  0.330 22.380  0 25  ILE 1 O   1 ? 
ATOM   187  C CB  . ILE A 1 25  ? -10.622 15.422  -8.507  0.330 23.290  0 25  ILE 1 CB  1 ? 
ATOM   188  C CG1 . ILE A 1 25  ? -9.614  15.494  -7.362  0.330 23.720  0 25  ILE 1 CG1 1 ? 
ATOM   189  C CG2 . ILE A 1 25  ? -10.210 16.302  -9.683  0.330 23.140  0 25  ILE 1 CG2 1 ? 
ATOM   190  C CD1 . ILE A 1 25  ? -8.269  14.877  -7.677  0.330 23.770  0 25  ILE 1 CD1 1 ? 
ATOM   191  N N   . ASP A 1 26  ? -13.553 16.755  -9.714  0.330 21.240  0 26  ASP 1 N   1 ? 
ATOM   192  C CA  . ASP A 1 26  ? -14.502 16.792  -10.856 0.330 22.160  0 26  ASP 1 CA  1 ? 
ATOM   193  C C   . ASP A 1 26  ? -13.732 17.154  -12.126 0.330 22.740  0 26  ASP 1 C   1 ? 
ATOM   194  O O   . ASP A 1 26  ? -12.781 17.953  -12.040 0.330 22.500  0 26  ASP 1 O   1 ? 
ATOM   195  C CB  . ASP A 1 26  ? -15.647 17.781  -10.619 0.330 23.700  0 26  ASP 1 CB  1 ? 
ATOM   196  C CG  . ASP A 1 26  ? -16.556 17.338  -9.490  0.330 25.080  0 26  ASP 1 CG  1 ? 
ATOM   197  O OD1 . ASP A 1 26  ? -16.296 16.249  -8.948  0.330 24.360  0 26  ASP 1 OD1 1 ? 
ATOM   198  O OD2 . ASP A 1 26  ? -17.515 18.078  -9.167  0.330 26.540  0 26  ASP 1 OD2 1 ? 
ATOM   199  N N   . GLY A 1 27  ? -14.115 16.548  -13.248 0.330 22.560  0 27  GLY 1 N   1 ? 
ATOM   200  C CA  . GLY A 1 27  ? -13.515 16.817  -14.565 0.330 22.120  0 27  GLY 1 CA  1 ? 
ATOM   201  C C   . GLY A 1 27  ? -14.569 17.221  -15.578 0.330 22.060  0 27  GLY 1 C   1 ? 
ATOM   202  O O   . GLY A 1 27  ? -15.667 16.645  -15.559 0.330 21.960  0 27  GLY 1 O   1 ? 
ATOM   203  N N   . ASP A 1 28  ? -14.206 18.147  -16.465 0.330 21.220  0 28  ASP 1 N   1 ? 
ATOM   204  C CA  . ASP A 1 28  ? -15.046 18.668  -17.566 0.330 20.680  0 28  ASP 1 CA  1 ? 
ATOM   205  C C   . ASP A 1 28  ? -14.122 18.906  -18.763 0.330 20.350  0 28  ASP 1 C   1 ? 
ATOM   206  O O   . ASP A 1 28  ? -13.203 19.747  -18.642 0.330 20.940  0 28  ASP 1 O   1 ? 
ATOM   207  C CB  . ASP A 1 28  ? -15.776 19.934  -17.106 0.330 22.140  0 28  ASP 1 CB  1 ? 
ATOM   208  C CG  . ASP A 1 28  ? -16.728 20.492  -18.144 0.330 22.120  0 28  ASP 1 CG  1 ? 
ATOM   209  O OD1 . ASP A 1 28  ? -16.448 20.318  -19.355 0.330 22.020  0 28  ASP 1 OD1 1 ? 
ATOM   210  O OD2 . ASP A 1 28  ? -17.749 21.074  -17.745 0.330 23.670  0 28  ASP 1 OD2 1 ? 
ATOM   211  N N   . GLY A 1 29  ? -14.313 18.191  -19.871 0.330 19.760  0 29  GLY 1 N   1 ? 
ATOM   212  C CA  . GLY A 1 29  ? -13.397 18.323  -21.020 0.330 20.170  0 29  GLY 1 CA  1 ? 
ATOM   213  C C   . GLY A 1 29  ? -14.037 17.945  -22.338 0.330 21.140  0 29  GLY 1 C   1 ? 
ATOM   214  O O   . GLY A 1 29  ? -15.263 17.711  -22.374 0.330 21.500  0 29  GLY 1 O   1 ? 
ATOM   215  N N   . THR A 1 30  ? -13.219 17.862  -23.387 0.330 21.350  0 30  THR 1 N   1 ? 
ATOM   216  C CA  . THR A 1 30  ? -13.641 17.532  -24.771 0.330 22.600  0 30  THR 1 CA  1 ? 
ATOM   217  C C   . THR A 1 30  ? -12.540 16.684  -25.409 0.330 23.450  0 30  THR 1 C   1 ? 
ATOM   218  O O   . THR A 1 30  ? -11.384 16.769  -24.947 0.330 22.260  0 30  THR 1 O   1 ? 
ATOM   219  C CB  . THR A 1 30  ? -13.920 18.796  -25.593 0.330 23.400  0 30  THR 1 CB  1 ? 
ATOM   220  O OG1 . THR A 1 30  ? -12.761 19.619  -25.496 0.330 23.750  0 30  THR 1 OG1 1 ? 
ATOM   221  C CG2 . THR A 1 30  ? -15.124 19.569  -25.105 0.330 24.570  0 30  THR 1 CG2 1 ? 
ATOM   222  N N   . GLY A 1 31  ? -12.883 15.886  -26.417 0.330 23.650  0 31  GLY 1 N   1 ? 
ATOM   223  C CA  . GLY A 1 31  ? -11.900 15.015  -27.082 0.330 25.110  0 31  GLY 1 CA  1 ? 
ATOM   224  C C   . GLY A 1 31  ? -12.341 14.642  -28.480 0.330 24.270  0 31  GLY 1 C   1 ? 
ATOM   225  O O   . GLY A 1 31  ? -13.551 14.724  -28.767 0.330 23.560  0 31  GLY 1 O   1 ? 
ATOM   226  N N   . LYS A 1 32  ? -11.372 14.276  -29.312 0.330 25.150  0 32  LYS 1 N   1 ? 
ATOM   227  C CA  . LYS A 1 32  ? -11.567 13.821  -30.713 0.330 26.450  0 32  LYS 1 CA  1 ? 
ATOM   228  C C   . LYS A 1 32  ? -11.191 12.347  -30.784 0.330 25.160  0 32  LYS 1 C   1 ? 
ATOM   229  O O   . LYS A 1 32  ? -10.029 12.018  -30.983 0.330 25.220  0 32  LYS 1 O   1 ? 
ATOM   230  C CB  . LYS A 1 32  ? -10.710 14.676  -31.654 0.330 26.810  0 32  LYS 1 CB  1 ? 
ATOM   231  C CG  . LYS A 1 32  ? -11.068 16.154  -31.664 0.330 30.760  0 32  LYS 1 CG  1 ? 
ATOM   232  C CD  . LYS A 1 32  ? -10.070 17.016  -32.417 0.330 33.260  0 32  LYS 1 CD  1 ? 
ATOM   233  C CE  . LYS A 1 32  ? -10.360 18.499  -32.299 0.330 36.240  0 32  LYS 1 CE  1 ? 
ATOM   234  N NZ  . LYS A 1 32  ? -11.656 18.858  -32.922 0.330 37.770  0 32  LYS 1 NZ  1 ? 
ATOM   235  N N   . PRO A 1 33  ? -12.153 11.421  -30.593 0.330 26.920  0 33  PRO 1 N   1 ? 
ATOM   236  C CA  . PRO A 1 33  ? -11.837 9.998   -30.454 0.330 27.210  0 33  PRO 1 CA  1 ? 
ATOM   237  C C   . PRO A 1 33  ? -10.989 9.454   -31.611 0.330 28.370  0 33  PRO 1 C   1 ? 
ATOM   238  O O   . PRO A 1 33  ? -10.090 8.666   -31.361 0.330 28.890  0 33  PRO 1 O   1 ? 
ATOM   239  C CB  . PRO A 1 33  ? -13.220 9.334   -30.387 0.330 27.010  0 33  PRO 1 CB  1 ? 
ATOM   240  C CG  . PRO A 1 33  ? -14.106 10.423  -29.809 0.330 27.660  0 33  PRO 1 CG  1 ? 
ATOM   241  C CD  . PRO A 1 33  ? -13.591 11.698  -30.446 0.330 27.110  0 33  PRO 1 CD  1 ? 
ATOM   242  N N   . PHE A 1 34  ? -11.265 9.912   -32.837 0.330 29.810  0 34  PHE 1 N   1 ? 
ATOM   243  C CA  . PHE A 1 34  ? -10.650 9.392   -34.090 0.330 29.240  0 34  PHE 1 CA  1 ? 
ATOM   244  C C   . PHE A 1 34  ? -9.247  9.974   -34.302 0.330 30.270  0 34  PHE 1 C   1 ? 
ATOM   245  O O   . PHE A 1 34  ? -8.481  9.394   -35.105 0.330 31.680  0 34  PHE 1 O   1 ? 
ATOM   246  C CB  . PHE A 1 34  ? -11.586 9.671   -35.268 0.330 30.010  0 34  PHE 1 CB  1 ? 
ATOM   247  C CG  . PHE A 1 34  ? -12.892 8.932   -35.155 0.330 31.060  0 34  PHE 1 CG  1 ? 
ATOM   248  C CD1 . PHE A 1 34  ? -12.945 7.561   -35.365 0.330 31.020  0 34  PHE 1 CD1 1 ? 
ATOM   249  C CD2 . PHE A 1 34  ? -14.051 9.592   -34.777 0.330 31.250  0 34  PHE 1 CD2 1 ? 
ATOM   250  C CE1 . PHE A 1 34  ? -14.138 6.872   -35.234 0.330 31.640  0 34  PHE 1 CE1 1 ? 
ATOM   251  C CE2 . PHE A 1 34  ? -15.242 8.896   -34.641 0.330 32.600  0 34  PHE 1 CE2 1 ? 
ATOM   252  C CZ  . PHE A 1 34  ? -15.285 7.540   -34.875 0.330 31.110  0 34  PHE 1 CZ  1 ? 
ATOM   253  N N   . GLU A 1 35  ? -8.903  11.066  -33.611 0.330 28.690  0 35  GLU 1 N   1 ? 
ATOM   254  C CA  . GLU A 1 35  ? -7.567  11.707  -33.713 0.330 29.020  0 35  GLU 1 CA  1 ? 
ATOM   255  C C   . GLU A 1 35  ? -6.719  11.286  -32.507 0.330 28.270  0 35  GLU 1 C   1 ? 
ATOM   256  O O   . GLU A 1 35  ? -5.497  11.520  -32.535 0.330 28.870  0 35  GLU 1 O   1 ? 
ATOM   257  C CB  . GLU A 1 35  ? -7.703  13.227  -33.792 0.330 32.620  0 35  GLU 1 CB  1 ? 
ATOM   258  C CG  . GLU A 1 35  ? -8.493  13.698  -34.999 0.330 36.150  0 35  GLU 1 CG  1 ? 
ATOM   259  C CD  . GLU A 1 35  ? -8.856  15.175  -34.980 0.330 39.330  0 35  GLU 1 CD  1 ? 
ATOM   260  O OE1 . GLU A 1 35  ? -10.023 15.491  -35.315 0.330 40.980  0 35  GLU 1 OE1 1 ? 
ATOM   261  O OE2 . GLU A 1 35  ? -7.976  16.004  -34.646 0.330 40.070  0 35  GLU 1 OE2 1 ? 
ATOM   262  N N   . GLY A 1 36  ? -7.355  10.706  -31.486 0.330 26.400  0 36  GLY 1 N   1 ? 
ATOM   263  C CA  . GLY A 1 36  ? -6.680  10.172  -30.286 0.330 26.280  0 36  GLY 1 CA  1 ? 
ATOM   264  C C   . GLY A 1 36  ? -6.245  11.275  -29.337 0.330 25.240  0 36  GLY 1 C   1 ? 
ATOM   265  O O   . GLY A 1 36  ? -5.211  11.103  -28.663 0.330 25.770  0 36  GLY 1 O   1 ? 
ATOM   266  N N   . LYS A 1 37  ? -7.022  12.357  -29.258 0.330 25.130  0 37  LYS 1 N   1 ? 
ATOM   267  C CA  . LYS A 1 37  ? -6.671  13.565  -28.466 0.330 26.060  0 37  LYS 1 CA  1 ? 
ATOM   268  C C   . LYS A 1 37  ? -7.820  13.908  -27.518 0.330 25.220  0 37  LYS 1 C   1 ? 
ATOM   269  O O   . LYS A 1 37  ? -8.979  13.793  -27.948 0.330 25.780  0 37  LYS 1 O   1 ? 
ATOM   270  C CB  . LYS A 1 37  ? -6.372  14.735  -29.404 0.330 27.950  0 37  LYS 1 CB  1 ? 
ATOM   271  C CG  . LYS A 1 37  ? -5.131  14.533  -30.261 0.330 31.510  0 37  LYS 1 CG  1 ? 
ATOM   272  C CD  . LYS A 1 37  ? -4.935  15.574  -31.345 0.330 34.420  0 37  LYS 1 CD  1 ? 
ATOM   273  C CE  . LYS A 1 37  ? -3.616  15.387  -32.072 0.330 36.540  0 37  LYS 1 CE  1 ? 
ATOM   274  N NZ  . LYS A 1 37  ? -3.497  16.285  -33.247 0.330 39.600  0 37  LYS 1 NZ  1 ? 
ATOM   275  N N   . GLN A 1 38  ? -7.490  14.319  -26.286 0.330 24.230  0 38  GLN 1 N   1 ? 
ATOM   276  C CA  . GLN A 1 38  ? -8.469  14.768  -25.264 0.330 23.400  0 38  GLN 1 CA  1 ? 
ATOM   277  C C   . GLN A 1 38  ? -7.793  15.793  -24.343 0.330 23.620  0 38  GLN 1 C   1 ? 
ATOM   278  O O   . GLN A 1 38  ? -6.577  15.693  -24.103 0.330 23.320  0 38  GLN 1 O   1 ? 
ATOM   279  C CB  . GLN A 1 38  ? -9.017  13.572  -24.485 0.330 23.610  0 38  GLN 1 CB  1 ? 
ATOM   280  C CG  . GLN A 1 38  ? -8.001  12.908  -23.560 0.330 23.920  0 38  GLN 1 CG  1 ? 
ATOM   281  C CD  . GLN A 1 38  ? -8.601  11.762  -22.778 0.330 23.990  0 38  GLN 1 CD  1 ? 
ATOM   282  O OE1 . GLN A 1 38  ? -8.081  10.652  -22.762 0.330 26.250  0 38  GLN 1 OE1 1 ? 
ATOM   283  N NE2 . GLN A 1 38  ? -9.716  12.018  -22.123 0.330 23.860  0 38  GLN 1 NE2 1 ? 
ATOM   284  N N   . SER A 1 39  ? -8.556  16.776  -23.879 0.330 23.800  0 39  SER 1 N   1 ? 
ATOM   285  C CA  . SER A 1 39  ? -8.114  17.786  -22.893 0.330 25.000  0 39  SER 1 CA  1 ? 
ATOM   286  C C   . SER A 1 39  ? -9.283  18.084  -21.960 0.330 25.300  0 39  SER 1 C   1 ? 
ATOM   287  O O   . SER A 1 39  ? -10.412 18.241  -22.463 0.330 25.910  0 39  SER 1 O   1 ? 
ATOM   288  C CB  . SER A 1 39  ? -7.615  19.024  -23.574 0.330 26.600  0 39  SER 1 CB  1 ? 
ATOM   289  O OG  . SER A 1 39  ? -8.571  19.480  -24.514 0.330 29.470  0 39  SER 1 OG  1 ? 
ATOM   290  N N   . MET A 1 40  ? -9.024  18.123  -20.656 0.330 23.930  0 40  MET 1 N   1 ? 
ATOM   291  C CA  . MET A 1 40  ? -10.077 18.324  -19.641 0.330 24.740  0 40  MET 1 CA  1 ? 
ATOM   292  C C   . MET A 1 40  ? -9.565  19.253  -18.542 0.330 22.950  0 40  MET 1 C   1 ? 
ATOM   293  O O   . MET A 1 40  ? -8.337  19.324  -18.323 0.330 22.430  0 40  MET 1 O   1 ? 
ATOM   294  C CB  . MET A 1 40  ? -10.525 16.995  -19.028 0.330 26.200  0 40  MET 1 CB  1 ? 
ATOM   295  C CG  . MET A 1 40  ? -9.444  16.231  -18.325 0.330 28.640  0 40  MET 1 CG  1 ? 
ATOM   296  S SD  . MET A 1 40  ? -10.068 14.573  -17.895 0.330 32.720  0 40  MET 1 SD  1 ? 
ATOM   297  C CE  . MET A 1 40  ? -9.870  13.740  -19.467 0.330 30.700  0 40  MET 1 CE  1 ? 
ATOM   298  N N   . ASP A 1 41  ? -10.502 19.952  -17.911 0.330 21.450  0 41  ASP 1 N   1 ? 
ATOM   299  C CA  . ASP A 1 41  ? -10.252 20.849  -16.759 0.330 22.150  0 41  ASP 1 CA  1 ? 
ATOM   300  C C   . ASP A 1 41  ? -10.663 20.107  -15.489 0.330 22.130  0 41  ASP 1 C   1 ? 
ATOM   301  O O   . ASP A 1 41  ? -11.803 19.612  -15.435 0.330 22.060  0 41  ASP 1 O   1 ? 
ATOM   302  C CB  . ASP A 1 41  ? -10.971 22.177  -16.969 0.330 22.140  0 41  ASP 1 CB  1 ? 
ATOM   303  C CG  . ASP A 1 41  ? -10.318 22.948  -18.096 0.330 22.810  0 41  ASP 1 CG  1 ? 
ATOM   304  O OD1 . ASP A 1 41  ? -10.525 22.547  -19.257 0.330 20.290  0 41  ASP 1 OD1 1 ? 
ATOM   305  O OD2 . ASP A 1 41  ? -9.551  23.898  -17.783 0.330 22.610  0 41  ASP 1 OD2 1 ? 
ATOM   306  N N   . LEU A 1 42  ? -9.737  20.017  -14.534 0.330 21.570  0 42  LEU 1 N   1 ? 
ATOM   307  C CA  . LEU A 1 42  ? -9.897  19.245  -13.281 0.330 22.340  0 42  LEU 1 CA  1 ? 
ATOM   308  C C   . LEU A 1 42  ? -9.908  20.220  -12.101 0.330 21.640  0 42  LEU 1 C   1 ? 
ATOM   309  O O   . LEU A 1 42  ? -9.083  21.160  -12.096 0.330 22.070  0 42  LEU 1 O   1 ? 
ATOM   310  C CB  . LEU A 1 42  ? -8.743  18.248  -13.179 0.330 24.100  0 42  LEU 1 CB  1 ? 
ATOM   311  C CG  . LEU A 1 42  ? -8.592  17.319  -14.384 0.330 25.030  0 42  LEU 1 CG  1 ? 
ATOM   312  C CD1 . LEU A 1 42  ? -7.264  16.584  -14.337 0.330 25.810  0 42  LEU 1 CD1 1 ? 
ATOM   313  C CD2 . LEU A 1 42  ? -9.757  16.343  -14.439 0.330 25.430  0 42  LEU 1 CD2 1 ? 
ATOM   314  N N   . GLU A 1 43  ? -10.822 20.005  -11.157 0.330 21.800  0 43  GLU 1 N   1 ? 
ATOM   315  C CA  . GLU A 1 43  ? -11.043 20.883  -9.978  0.330 22.080  0 43  GLU 1 CA  1 ? 
ATOM   316  C C   . GLU A 1 43  ? -11.167 19.995  -8.741  0.330 21.270  0 43  GLU 1 C   1 ? 
ATOM   317  O O   . GLU A 1 43  ? -12.091 19.153  -8.708  0.330 21.590  0 43  GLU 1 O   1 ? 
ATOM   318  C CB  . GLU A 1 43  ? -12.301 21.736  -10.185 0.330 23.760  0 43  GLU 1 CB  1 ? 
ATOM   319  C CG  . GLU A 1 43  ? -12.517 22.803  -9.113  0.330 24.850  0 43  GLU 1 CG  1 ? 
ATOM   320  C CD  . GLU A 1 43  ? -13.877 23.499  -9.161  0.330 24.790  0 43  GLU 1 CD  1 ? 
ATOM   321  O OE1 . GLU A 1 43  ? -14.536 23.416  -10.215 0.330 22.930  0 43  GLU 1 OE1 1 ? 
ATOM   322  O OE2 . GLU A 1 43  ? -14.264 24.142  -8.151  0.330 24.140  0 43  GLU 1 OE2 1 ? 
ATOM   323  N N   . VAL A 1 44  ? -10.255 20.149  -7.782  0.330 21.400  0 44  VAL 1 N   1 ? 
ATOM   324  C CA  . VAL A 1 44  ? -10.335 19.469  -6.462  0.330 21.020  0 44  VAL 1 CA  1 ? 
ATOM   325  C C   . VAL A 1 44  ? -11.533 20.068  -5.720  0.330 21.370  0 44  VAL 1 C   1 ? 
ATOM   326  O O   . VAL A 1 44  ? -11.528 21.284  -5.487  0.330 21.030  0 44  VAL 1 O   1 ? 
ATOM   327  C CB  . VAL A 1 44  ? -9.030  19.620  -5.659  0.330 21.640  0 44  VAL 1 CB  1 ? 
ATOM   328  C CG1 . VAL A 1 44  ? -9.164  18.986  -4.288  0.330 22.330  0 44  VAL 1 CG1 1 ? 
ATOM   329  C CG2 . VAL A 1 44  ? -7.839  19.050  -6.402  0.330 22.140  0 44  VAL 1 CG2 1 ? 
ATOM   330  N N   . LYS A 1 45  ? -12.528 19.245  -5.377  0.330 22.030  0 45  LYS 1 N   1 ? 
ATOM   331  C CA  . LYS A 1 45  ? -13.796 19.692  -4.738  0.330 22.440  0 45  LYS 1 CA  1 ? 
ATOM   332  C C   . LYS A 1 45  ? -13.722 19.472  -3.222  0.330 23.070  0 45  LYS 1 C   1 ? 
ATOM   333  O O   . LYS A 1 45  ? -14.343 20.256  -2.481  0.330 24.740  0 45  LYS 1 O   1 ? 
ATOM   334  C CB  . LYS A 1 45  ? -14.981 18.951  -5.365  0.330 23.750  0 45  LYS 1 CB  1 ? 
ATOM   335  C CG  . LYS A 1 45  ? -15.365 19.436  -6.756  0.330 26.070  0 45  LYS 1 CG  1 ? 
ATOM   336  C CD  . LYS A 1 45  ? -15.684 20.917  -6.796  0.330 28.860  0 45  LYS 1 CD  1 ? 
ATOM   337  C CE  . LYS A 1 45  ? -15.960 21.439  -8.191  0.330 32.330  0 45  LYS 1 CE  1 ? 
ATOM   338  N NZ  . LYS A 1 45  ? -17.009 20.642  -8.873  0.330 34.870  0 45  LYS 1 NZ  1 ? 
ATOM   339  N N   . GLU A 1 46  ? -12.990 18.453  -2.776  0.330 23.110  0 46  GLU 1 N   1 ? 
ATOM   340  C CA  . GLU A 1 46  ? -12.790 18.150  -1.333  0.330 24.590  0 46  GLU 1 CA  1 ? 
ATOM   341  C C   . GLU A 1 46  ? -11.370 17.650  -1.085  0.330 24.390  0 46  GLU 1 C   1 ? 
ATOM   342  O O   . GLU A 1 46  ? -10.830 16.987  -1.990  0.330 24.370  0 46  GLU 1 O   1 ? 
ATOM   343  C CB  . GLU A 1 46  ? -13.752 17.059  -0.864  0.330 25.660  0 46  GLU 1 CB  1 ? 
ATOM   344  C CG  . GLU A 1 46  ? -15.191 17.393  -1.133  0.330 27.790  0 46  GLU 1 CG  1 ? 
ATOM   345  C CD  . GLU A 1 46  ? -16.184 16.590  -0.309  0.330 28.900  0 46  GLU 1 CD  1 ? 
ATOM   346  O OE1 . GLU A 1 46  ? -17.383 16.731  -0.585  0.330 31.090  0 46  GLU 1 OE1 1 ? 
ATOM   347  O OE2 . GLU A 1 46  ? -15.754 15.841  0.596   0.330 28.290  0 46  GLU 1 OE2 1 ? 
ATOM   348  N N   . GLY A 1 47  ? -10.824 17.923  0.107   0.330 25.070  0 47  GLY 1 N   1 ? 
ATOM   349  C CA  . GLY A 1 47  ? -9.525  17.400  0.590   0.330 25.220  0 47  GLY 1 CA  1 ? 
ATOM   350  C C   . GLY A 1 47  ? -8.329  18.262  0.196   0.330 27.900  0 47  GLY 1 C   1 ? 
ATOM   351  O O   . GLY A 1 47  ? -7.202  17.924  0.626   0.330 28.390  0 47  GLY 1 O   1 ? 
ATOM   352  N N   . GLY A 1 48  ? -8.548  19.322  -0.600  0.330 25.800  0 48  GLY 1 N   1 ? 
ATOM   353  C CA  . GLY A 1 48  ? -7.491  20.241  -1.065  0.330 25.100  0 48  GLY 1 CA  1 ? 
ATOM   354  C C   . GLY A 1 48  ? -6.989  21.149  0.055   0.330 25.670  0 48  GLY 1 C   1 ? 
ATOM   355  O O   . GLY A 1 48  ? -7.736  21.503  0.966   0.330 25.060  0 48  GLY 1 O   1 ? 
ATOM   356  N N   . PRO A 1 49  ? -5.708  21.573  0.012   0.330 25.540  0 49  PRO 1 N   1 ? 
ATOM   357  C CA  . PRO A 1 49  ? -4.794  21.186  -1.063  0.330 25.420  0 49  PRO 1 CA  1 ? 
ATOM   358  C C   . PRO A 1 49  ? -4.259  19.765  -0.841  0.330 23.700  0 49  PRO 1 C   1 ? 
ATOM   359  O O   . PRO A 1 49  ? -4.014  19.394  0.284   0.330 24.250  0 49  PRO 1 O   1 ? 
ATOM   360  C CB  . PRO A 1 49  ? -3.675  22.234  -0.957  0.330 25.570  0 49  PRO 1 CB  1 ? 
ATOM   361  C CG  . PRO A 1 49  ? -3.635  22.574  0.525   0.330 26.730  0 49  PRO 1 CG  1 ? 
ATOM   362  C CD  . PRO A 1 49  ? -5.078  22.482  0.982   0.330 27.300  0 49  PRO 1 CD  1 ? 
ATOM   363  N N   . LEU A 1 50  ? -4.100  19.008  -1.923  0.330 23.460  0 50  LEU 1 N   1 ? 
ATOM   364  C CA  . LEU A 1 50  ? -3.626  17.602  -1.894  0.330 23.250  0 50  LEU 1 CA  1 ? 
ATOM   365  C C   . LEU A 1 50  ? -2.206  17.557  -1.352  0.330 22.280  0 50  LEU 1 C   1 ? 
ATOM   366  O O   . LEU A 1 50  ? -1.337  18.295  -1.807  0.330 22.360  0 50  LEU 1 O   1 ? 
ATOM   367  C CB  . LEU A 1 50  ? -3.673  17.020  -3.308  0.330 23.330  0 50  LEU 1 CB  1 ? 
ATOM   368  C CG  . LEU A 1 50  ? -5.064  16.823  -3.902  0.330 23.660  0 50  LEU 1 CG  1 ? 
ATOM   369  C CD1 . LEU A 1 50  ? -4.970  16.071  -5.218  0.330 25.290  0 50  LEU 1 CD1 1 ? 
ATOM   370  C CD2 . LEU A 1 50  ? -5.975  16.095  -2.928  0.330 23.440  0 50  LEU 1 CD2 1 ? 
ATOM   371  N N   . PRO A 1 51  ? -1.942  16.685  -0.354  0.330 23.530  0 51  PRO 1 N   1 ? 
ATOM   372  C CA  . PRO A 1 51  ? -0.606  16.549  0.230   0.330 23.530  0 51  PRO 1 CA  1 ? 
ATOM   373  C C   . PRO A 1 51  ? 0.302   15.541  -0.489  0.330 23.130  0 51  PRO 1 C   1 ? 
ATOM   374  O O   . PRO A 1 51  ? 1.248   15.081  0.120   0.330 23.940  0 51  PRO 1 O   1 ? 
ATOM   375  C CB  . PRO A 1 51  ? -0.923  16.047  1.643   0.330 23.840  0 51  PRO 1 CB  1 ? 
ATOM   376  C CG  . PRO A 1 51  ? -2.172  15.211  1.460   0.330 24.440  0 51  PRO 1 CG  1 ? 
ATOM   377  C CD  . PRO A 1 51  ? -2.940  15.846  0.320   0.330 24.740  0 51  PRO 1 CD  1 ? 
ATOM   378  N N   . PHE A 1 52  ? 0.006   15.230  -1.752  0.330 22.090  0 52  PHE 1 N   1 ? 
ATOM   379  C CA  . PHE A 1 52  ? 0.813   14.305  -2.585  0.330 21.490  0 52  PHE 1 CA  1 ? 
ATOM   380  C C   . PHE A 1 52  ? 0.843   14.812  -4.031  0.330 20.380  0 52  PHE 1 C   1 ? 
ATOM   381  O O   . PHE A 1 52  ? -0.027  15.627  -4.415  0.330 20.220  0 52  PHE 1 O   1 ? 
ATOM   382  C CB  . PHE A 1 52  ? 0.263   12.882  -2.499  0.330 21.140  0 52  PHE 1 CB  1 ? 
ATOM   383  C CG  . PHE A 1 52  ? -1.153  12.738  -2.984  0.330 21.570  0 52  PHE 1 CG  1 ? 
ATOM   384  C CD1 . PHE A 1 52  ? -1.441  12.740  -4.335  0.330 21.880  0 52  PHE 1 CD1 1 ? 
ATOM   385  C CD2 . PHE A 1 52  ? -2.208  12.631  -2.090  0.330 22.810  0 52  PHE 1 CD2 1 ? 
ATOM   386  C CE1 . PHE A 1 52  ? -2.747  12.628  -4.785  0.330 22.690  0 52  PHE 1 CE1 1 ? 
ATOM   387  C CE2 . PHE A 1 52  ? -3.513  12.530  -2.539  0.330 22.700  0 52  PHE 1 CE2 1 ? 
ATOM   388  C CZ  . PHE A 1 52  ? -3.783  12.527  -3.887  0.330 22.930  0 52  PHE 1 CZ  1 ? 
ATOM   389  N N   . ALA A 1 53  ? 1.823   14.335  -4.802  0.330 20.230  0 53  ALA 1 N   1 ? 
ATOM   390  C CA  . ALA A 1 53  ? 2.073   14.726  -6.208  0.330 20.250  0 53  ALA 1 CA  1 ? 
ATOM   391  C C   . ALA A 1 53  ? 0.831   14.422  -7.049  0.330 21.320  0 53  ALA 1 C   1 ? 
ATOM   392  O O   . ALA A 1 53  ? 0.436   13.238  -7.138  0.330 22.360  0 53  ALA 1 O   1 ? 
ATOM   393  C CB  . ALA A 1 53  ? 3.293   14.008  -6.729  0.330 20.610  0 53  ALA 1 CB  1 ? 
ATOM   394  N N   . PHE A 1 54  ? 0.244   15.457  -7.655  0.330 20.890  0 54  PHE 1 N   1 ? 
ATOM   395  C CA  . PHE A 1 54  ? -0.955  15.355  -8.521  0.330 21.160  0 54  PHE 1 CA  1 ? 
ATOM   396  C C   . PHE A 1 54  ? -0.692  14.316  -9.616  0.330 20.450  0 54  PHE 1 C   1 ? 
ATOM   397  O O   . PHE A 1 54  ? -1.627  13.624  -10.024 0.330 19.950  0 54  PHE 1 O   1 ? 
ATOM   398  C CB  . PHE A 1 54  ? -1.301  16.708  -9.149  0.330 20.600  0 54  PHE 1 CB  1 ? 
ATOM   399  C CG  . PHE A 1 54  ? -2.716  16.807  -9.662  0.330 21.670  0 54  PHE 1 CG  1 ? 
ATOM   400  C CD1 . PHE A 1 54  ? -3.745  17.232  -8.832  0.330 21.940  0 54  PHE 1 CD1 1 ? 
ATOM   401  C CD2 . PHE A 1 54  ? -3.032  16.432  -10.960 0.330 20.980  0 54  PHE 1 CD2 1 ? 
ATOM   402  C CE1 . PHE A 1 54  ? -5.046  17.318  -9.301  0.330 21.890  0 54  PHE 1 CE1 1 ? 
ATOM   403  C CE2 . PHE A 1 54  ? -4.330  16.531  -11.429 0.330 21.360  0 54  PHE 1 CE2 1 ? 
ATOM   404  C CZ  . PHE A 1 54  ? -5.334  16.960  -10.598 0.330 21.830  0 54  PHE 1 CZ  1 ? 
ATOM   405  N N   . ASP A 1 55  ? 0.563   14.215  -10.063 0.330 21.100  0 55  ASP 1 N   1 ? 
ATOM   406  C CA  . ASP A 1 55  ? 0.965   13.412  -11.248 0.330 20.340  0 55  ASP 1 CA  1 ? 
ATOM   407  C C   . ASP A 1 55  ? 0.522   11.951  -11.107 0.330 20.400  0 55  ASP 1 C   1 ? 
ATOM   408  O O   . ASP A 1 55  ? 0.290   11.328  -12.144 0.330 20.900  0 55  ASP 1 O   1 ? 
ATOM   409  C CB  . ASP A 1 55  ? 2.474   13.499  -11.480 0.330 20.400  0 55  ASP 1 CB  1 ? 
ATOM   410  C CG  . ASP A 1 55  ? 2.897   14.767  -12.200 0.330 20.550  0 55  ASP 1 CG  1 ? 
ATOM   411  O OD1 . ASP A 1 55  ? 2.166   15.187  -13.127 0.330 20.870  0 55  ASP 1 OD1 1 ? 
ATOM   412  O OD2 . ASP A 1 55  ? 3.942   15.324  -11.829 0.330 21.190  0 55  ASP 1 OD2 1 ? 
ATOM   413  N N   . ILE A 1 56  ? 0.444   11.401  -9.892  0.330 20.410  0 56  ILE 1 N   1 ? 
ATOM   414  C CA  . ILE A 1 56  ? 0.114   9.957   -9.690  0.330 20.970  0 56  ILE 1 CA  1 ? 
ATOM   415  C C   . ILE A 1 56  ? -1.352  9.714   -10.059 0.330 20.750  0 56  ILE 1 C   1 ? 
ATOM   416  O O   . ILE A 1 56  ? -1.736  8.553   -10.214 0.330 22.580  0 56  ILE 1 O   1 ? 
ATOM   417  C CB  . ILE A 1 56  ? 0.420   9.462   -8.263  0.330 21.310  0 56  ILE 1 CB  1 ? 
ATOM   418  C CG1 . ILE A 1 56  ? -0.494  10.094  -7.210  0.330 22.580  0 56  ILE 1 CG1 1 ? 
ATOM   419  C CG2 . ILE A 1 56  ? 1.892   9.657   -7.939  0.330 22.560  0 56  ILE 1 CG2 1 ? 
ATOM   420  C CD1 . ILE A 1 56  ? -0.553  9.312   -5.914  0.330 22.510  0 56  ILE 1 CD1 1 ? 
ATOM   421  N N   . LEU A 1 57  ? -2.135  10.771  -10.241 0.330 19.590  0 57  LEU 1 N   1 ? 
ATOM   422  C CA  . LEU A 1 57  ? -3.583  10.652  -10.517 0.330 19.950  0 57  LEU 1 CA  1 ? 
ATOM   423  C C   . LEU A 1 57  ? -3.849  10.635  -12.026 0.330 19.850  0 57  LEU 1 C   1 ? 
ATOM   424  O O   . LEU A 1 57  ? -4.872  10.069  -12.429 0.330 19.940  0 57  LEU 1 O   1 ? 
ATOM   425  C CB  . LEU A 1 57  ? -4.304  11.838  -9.869  0.330 20.020  0 57  LEU 1 CB  1 ? 
ATOM   426  C CG  . LEU A 1 57  ? -4.306  11.874  -8.347  0.330 20.700  0 57  LEU 1 CG  1 ? 
ATOM   427  C CD1 . LEU A 1 57  ? -5.230  12.980  -7.871  0.330 21.400  0 57  LEU 1 CD1 1 ? 
ATOM   428  C CD2 . LEU A 1 57  ? -4.721  10.541  -7.751  0.330 20.840  0 57  LEU 1 CD2 1 ? 
ATOM   429  N N   . THR A 1 58  ? -2.991  11.265  -12.825 0.330 19.090  0 58  THR 1 N   1 ? 
ATOM   430  C CA  . THR A 1 58  ? -3.379  11.802  -14.157 0.330 19.920  0 58  THR 1 CA  1 ? 
ATOM   431  C C   . THR A 1 58  ? -3.821  10.664  -15.089 0.330 20.100  0 58  THR 1 C   1 ? 
ATOM   432  O O   . THR A 1 58  ? -4.812  10.860  -15.820 0.330 21.730  0 58  THR 1 O   1 ? 
ATOM   433  C CB  . THR A 1 58  ? -2.265  12.688  -14.734 0.330 19.600  0 58  THR 1 CB  1 ? 
ATOM   434  O OG1 . THR A 1 58  ? -1.003  12.027  -14.621 0.330 20.190  0 58  THR 1 OG1 1 ? 
ATOM   435  C CG2 . THR A 1 58  ? -2.187  14.023  -14.029 0.330 19.890  0 58  THR 1 CG2 1 ? 
ATOM   436  N N   . THR A 1 59  ? -3.122  9.528   -15.105 0.330 21.230  0 59  THR 1 N   1 ? 
ATOM   437  C CA  . THR A 1 59  ? -3.448  8.414   -16.036 0.330 21.750  0 59  THR 1 CA  1 ? 
ATOM   438  C C   . THR A 1 59  ? -4.828  7.832   -15.699 0.330 20.790  0 59  THR 1 C   1 ? 
ATOM   439  O O   . THR A 1 59  ? -5.408  7.151   -16.573 0.330 20.390  0 59  THR 1 O   1 ? 
ATOM   440  C CB  . THR A 1 59  ? -2.362  7.336   -16.057 0.330 23.010  0 59  THR 1 CB  1 ? 
ATOM   441  O OG1 . THR A 1 59  ? -2.468  6.611   -14.836 0.330 23.120  0 59  THR 1 OG1 1 ? 
ATOM   442  C CG2 . THR A 1 59  ? -0.968  7.899   -16.237 0.330 23.240  0 59  THR 1 CG2 1 ? 
ATOM   443  N N   . ALA A 1 60  ? -5.364  8.110   -14.505 0.330 20.040  0 60  ALA 1 N   1 ? 
ATOM   444  C CA  . ALA A 1 60  ? -6.720  7.666   -14.107 0.330 19.740  0 60  ALA 1 CA  1 ? 
ATOM   445  C C   . ALA A 1 60  ? -7.757  8.598   -14.736 0.330 19.390  0 60  ALA 1 C   1 ? 
ATOM   446  O O   . ALA A 1 60  ? -8.853  8.109   -15.053 0.330 19.120  0 60  ALA 1 O   1 ? 
ATOM   447  C CB  . ALA A 1 60  ? -6.870  7.586   -12.609 0.330 20.490  0 60  ALA 1 CB  1 ? 
ATOM   448  N N   . PHE A 1 61  ? -7.411  9.875   -14.939 0.330 18.720  0 61  PHE 1 N   1 ? 
ATOM   449  C CA  . PHE A 1 61  ? -8.244  10.857  -15.676 0.330 18.360  0 61  PHE 1 CA  1 ? 
ATOM   450  C C   . PHE A 1 61  ? -8.153  10.562  -17.176 0.330 17.510  0 61  PHE 1 C   1 ? 
ATOM   451  O O   . PHE A 1 61  ? -9.161  10.720  -17.849 0.330 16.760  0 61  PHE 1 O   1 ? 
ATOM   452  C CB  . PHE A 1 61  ? -7.815  12.295  -15.375 0.330 19.830  0 61  PHE 1 CB  1 ? 
ATOM   453  C CG  . PHE A 1 61  ? -7.935  12.659  -13.919 0.330 19.970  0 61  PHE 1 CG  1 ? 
ATOM   454  C CD1 . PHE A 1 61  ? -9.134  12.498  -13.253 0.330 21.540  0 61  PHE 1 CD1 1 ? 
ATOM   455  C CD2 . PHE A 1 61  ? -6.859  13.175  -13.223 0.330 21.300  0 61  PHE 1 CD2 1 ? 
ATOM   456  C CE1 . PHE A 1 61  ? -9.250  12.846  -11.915 0.330 21.540  0 61  PHE 1 CE1 1 ? 
ATOM   457  C CE2 . PHE A 1 61  ? -6.979  13.525  -11.889 0.330 20.870  0 61  PHE 1 CE2 1 ? 
ATOM   458  C CZ  . PHE A 1 61  ? -8.169  13.342  -11.239 0.330 20.600  0 61  PHE 1 CZ  1 ? 
HETATM 459  N N1  . PIA A 1 62  ? -7.328  10.266  -17.711 0.330 17.410  0 64  PIA 1 N1  1 ? 
HETATM 460  C CA1 . PIA A 1 62  ? -6.850  10.021  -19.093 0.330 17.810  0 64  PIA 1 CA1 1 ? 
HETATM 461  C CB1 . PIA A 1 62  ? -5.867  11.097  -19.557 0.330 17.670  0 64  PIA 1 CB1 1 ? 
HETATM 462  C C1  . PIA A 1 62  ? -6.270  8.641   -19.200 0.330 17.800  0 64  PIA 1 C1  1 ? 
HETATM 463  N N2  . PIA A 1 62  ? -4.999  8.354   -19.488 0.330 17.800  0 64  PIA 1 N2  1 ? 
HETATM 464  N N3  . PIA A 1 62  ? -7.030  7.505   -18.988 0.330 18.520  0 64  PIA 1 N3  1 ? 
HETATM 465  C C2  . PIA A 1 62  ? -6.215  6.400   -19.102 0.330 18.520  0 64  PIA 1 C2  1 ? 
HETATM 466  O O2  . PIA A 1 62  ? -6.580  5.248   -18.937 0.330 18.910  0 64  PIA 1 O2  1 ? 
HETATM 467  C CA2 . PIA A 1 62  ? -4.881  6.951   -19.450 0.330 18.520  0 64  PIA 1 CA2 1 ? 
HETATM 468  C CA3 . PIA A 1 62  ? -8.439  7.522   -18.599 0.330 17.740  0 64  PIA 1 CA3 1 ? 
HETATM 469  C C3  . PIA A 1 62  ? -9.375  6.662   -19.445 0.330 17.550  0 64  PIA 1 C3  1 ? 
HETATM 470  O O3  . PIA A 1 62  ? -10.056 5.809   -18.819 0.330 15.830  0 64  PIA 1 O3  1 ? 
HETATM 471  C CB2 . PIA A 1 62  ? -3.812  6.168   -19.696 0.330 18.790  0 64  PIA 1 CB2 1 ? 
HETATM 472  C CG2 . PIA A 1 62  ? -2.412  6.517   -19.896 0.330 18.890  0 64  PIA 1 CG2 1 ? 
HETATM 473  C CD1 . PIA A 1 62  ? -2.026  7.847   -20.097 0.330 20.260  0 64  PIA 1 CD1 1 ? 
HETATM 474  C CD2 . PIA A 1 62  ? -1.408  5.546   -19.916 0.330 19.910  0 64  PIA 1 CD2 1 ? 
HETATM 475  C CE1 . PIA A 1 62  ? -0.707  8.196   -20.296 0.330 19.810  0 64  PIA 1 CE1 1 ? 
HETATM 476  C CE2 . PIA A 1 62  ? -0.085  5.886   -20.108 0.330 19.570  0 64  PIA 1 CE2 1 ? 
HETATM 477  C CZ  . PIA A 1 62  ? 0.272   7.218   -20.287 0.330 19.870  0 64  PIA 1 CZ  1 ? 
HETATM 478  O OH  . PIA A 1 62  ? 1.564   7.586   -20.502 0.330 20.800  0 64  PIA 1 OH  1 ? 
ATOM   479  N N   . ASN A 1 63  ? -9.376  6.733   -20.429 0.330 18.030  0 65  ASN 1 N   1 ? 
ATOM   480  C CA  . ASN A 1 63  ? -10.351 6.253   -21.423 0.330 18.330  0 65  ASN 1 CA  1 ? 
ATOM   481  C C   . ASN A 1 63  ? -9.640  6.077   -22.772 0.330 19.290  0 65  ASN 1 C   1 ? 
ATOM   482  O O   . ASN A 1 63  ? -9.339  7.094   -23.424 0.330 18.900  0 65  ASN 1 O   1 ? 
ATOM   483  C CB  . ASN A 1 63  ? -11.523 7.234   -21.507 0.330 18.060  0 65  ASN 1 CB  1 ? 
ATOM   484  C CG  . ASN A 1 63  ? -12.605 6.812   -22.474 0.330 17.790  0 65  ASN 1 CG  1 ? 
ATOM   485  O OD1 . ASN A 1 63  ? -12.445 5.848   -23.223 0.330 17.590  0 65  ASN 1 OD1 1 ? 
ATOM   486  N ND2 . ASN A 1 63  ? -13.696 7.560   -22.491 0.330 18.110  0 65  ASN 1 ND2 1 ? 
ATOM   487  N N   . ARG A 1 64  ? -9.398  4.830   -23.180 0.330 20.160  0 66  ARG 1 N   1 ? 
ATOM   488  C CA  . ARG A 1 64  ? -8.625  4.465   -24.395 0.330 21.030  0 66  ARG 1 CA  1 ? 
ATOM   489  C C   . ARG A 1 64  ? -9.505  4.616   -25.645 0.330 21.850  0 66  ARG 1 C   1 ? 
ATOM   490  O O   . ARG A 1 64  ? -9.002  4.338   -26.751 0.330 21.670  0 66  ARG 1 O   1 ? 
ATOM   491  C CB  . ARG A 1 64  ? -8.091  3.034   -24.245 0.330 21.380  0 66  ARG 1 CB  1 ? 
ATOM   492  C CG  . ARG A 1 64  ? -6.937  2.693   -25.179 0.330 22.080  0 66  ARG 1 CG  1 ? 
ATOM   493  C CD  . ARG A 1 64  ? -5.605  3.265   -24.729 0.330 22.380  0 66  ARG 1 CD  1 ? 
ATOM   494  N NE  . ARG A 1 64  ? -5.395  2.994   -23.316 0.330 22.280  0 66  ARG 1 NE  1 ? 
ATOM   495  C CZ  . ARG A 1 64  ? -5.805  3.788   -22.343 0.330 22.730  0 66  ARG 1 CZ  1 ? 
ATOM   496  N NH1 . ARG A 1 64  ? -6.410  4.924   -22.638 0.330 23.080  0 66  ARG 1 NH1 1 ? 
ATOM   497  N NH2 . ARG A 1 64  ? -5.593  3.450   -21.082 0.330 24.920  0 66  ARG 1 NH2 1 ? 
ATOM   498  N N   . VAL A 1 65  ? -10.768 5.038   -25.487 0.330 22.160  0 67  VAL 1 N   1 ? 
ATOM   499  C CA  . VAL A 1 65  ? -11.661 5.405   -26.625 0.330 22.090  0 67  VAL 1 CA  1 ? 
ATOM   500  C C   . VAL A 1 65  ? -11.034 6.601   -27.355 0.330 22.340  0 67  VAL 1 C   1 ? 
ATOM   501  O O   . VAL A 1 65  ? -11.278 6.750   -28.566 0.330 22.000  0 67  VAL 1 O   1 ? 
ATOM   502  C CB  . VAL A 1 65  ? -13.106 5.684   -26.161 0.330 23.390  0 67  VAL 1 CB  1 ? 
ATOM   503  C CG1 . VAL A 1 65  ? -13.357 7.167   -25.947 0.330 24.250  0 67  VAL 1 CG1 1 ? 
ATOM   504  C CG2 . VAL A 1 65  ? -14.129 5.110   -27.126 0.330 24.230  0 67  VAL 1 CG2 1 ? 
ATOM   505  N N   . PHE A 1 66  ? -10.235 7.407   -26.642 0.330 22.560  0 68  PHE 1 N   1 ? 
ATOM   506  C CA  . PHE A 1 66  ? -9.404  8.502   -27.208 0.330 22.390  0 68  PHE 1 CA  1 ? 
ATOM   507  C C   . PHE A 1 66  ? -8.026  7.928   -27.555 0.330 22.620  0 68  PHE 1 C   1 ? 
ATOM   508  O O   . PHE A 1 66  ? -7.086  8.006   -26.746 0.330 22.600  0 68  PHE 1 O   1 ? 
ATOM   509  C CB  . PHE A 1 66  ? -9.326  9.695   -26.248 0.330 22.500  0 68  PHE 1 CB  1 ? 
ATOM   510  C CG  . PHE A 1 66  ? -10.655 10.335  -25.944 0.330 23.100  0 68  PHE 1 CG  1 ? 
ATOM   511  C CD1 . PHE A 1 66  ? -11.276 11.159  -26.870 0.330 24.170  0 68  PHE 1 CD1 1 ? 
ATOM   512  C CD2 . PHE A 1 66  ? -11.291 10.103  -24.734 0.330 23.280  0 68  PHE 1 CD2 1 ? 
ATOM   513  C CE1 . PHE A 1 66  ? -12.504 11.738  -26.590 0.330 25.270  0 68  PHE 1 CE1 1 ? 
ATOM   514  C CE2 . PHE A 1 66  ? -12.520 10.679  -24.460 0.330 24.080  0 68  PHE 1 CE2 1 ? 
ATOM   515  C CZ  . PHE A 1 66  ? -13.122 11.496  -25.385 0.330 25.250  0 68  PHE 1 CZ  1 ? 
ATOM   516  N N   . ALA A 1 67  ? -7.933  7.320   -28.734 0.330 22.830  0 69  ALA 1 N   1 ? 
ATOM   517  C CA  . ALA A 1 67  ? -6.702  6.748   -29.320 0.330 23.770  0 69  ALA 1 CA  1 ? 
ATOM   518  C C   . ALA A 1 67  ? -6.968  6.513   -30.803 0.330 23.680  0 69  ALA 1 C   1 ? 
ATOM   519  O O   . ALA A 1 67  ? -8.038  5.979   -31.120 0.330 24.660  0 69  ALA 1 O   1 ? 
ATOM   520  C CB  . ALA A 1 67  ? -6.316  5.463   -28.633 0.330 24.350  0 69  ALA 1 CB  1 ? 
ATOM   521  N N   . LYS A 1 68  ? -6.045  6.936   -31.663 0.330 24.770  0 70  LYS 1 N   1 ? 
ATOM   522  C CA  . LYS A 1 68  ? -6.147  6.766   -33.134 0.330 25.750  0 70  LYS 1 CA  1 ? 
ATOM   523  C C   . LYS A 1 68  ? -5.799  5.315   -33.470 0.330 25.880  0 70  LYS 1 C   1 ? 
ATOM   524  O O   . LYS A 1 68  ? -4.613  4.936   -33.320 0.330 23.640  0 70  LYS 1 O   1 ? 
ATOM   525  C CB  . LYS A 1 68  ? -5.228  7.764   -33.843 0.330 28.880  0 70  LYS 1 CB  1 ? 
ATOM   526  C CG  . LYS A 1 68  ? -5.381  7.810   -35.358 0.330 32.540  0 70  LYS 1 CG  1 ? 
ATOM   527  C CD  . LYS A 1 68  ? -4.793  9.051   -36.003 0.330 36.000  0 70  LYS 1 CD  1 ? 
ATOM   528  C CE  . LYS A 1 68  ? -3.283  9.122   -35.896 0.330 40.170  0 70  LYS 1 CE  1 ? 
ATOM   529  N NZ  . LYS A 1 68  ? -2.723  10.284  -36.637 0.330 43.930  0 70  LYS 1 NZ  1 ? 
ATOM   530  N N   . TYR A 1 69  ? -6.803  4.542   -33.892 0.330 24.420  0 71  TYR 1 N   1 ? 
ATOM   531  C CA  . TYR A 1 69  ? -6.673  3.116   -34.276 0.330 25.070  0 71  TYR 1 CA  1 ? 
ATOM   532  C C   . TYR A 1 69  ? -6.684  3.001   -35.794 0.330 26.390  0 71  TYR 1 C   1 ? 
ATOM   533  O O   . TYR A 1 69  ? -7.610  3.490   -36.440 0.330 26.520  0 71  TYR 1 O   1 ? 
ATOM   534  C CB  . TYR A 1 69  ? -7.811  2.286   -33.687 0.330 24.860  0 71  TYR 1 CB  1 ? 
ATOM   535  C CG  . TYR A 1 69  ? -7.494  1.595   -32.390 0.330 24.930  0 71  TYR 1 CG  1 ? 
ATOM   536  C CD1 . TYR A 1 69  ? -7.603  2.265   -31.184 0.330 25.270  0 71  TYR 1 CD1 1 ? 
ATOM   537  C CD2 . TYR A 1 69  ? -7.119  0.259   -32.365 0.330 25.200  0 71  TYR 1 CD2 1 ? 
ATOM   538  C CE1 . TYR A 1 69  ? -7.318  1.635   -29.986 0.330 24.820  0 71  TYR 1 CE1 1 ? 
ATOM   539  C CE2 . TYR A 1 69  ? -6.840  -0.388  -31.172 0.330 25.130  0 71  TYR 1 CE2 1 ? 
ATOM   540  C CZ  . TYR A 1 69  ? -6.939  0.304   -29.979 0.330 24.970  0 71  TYR 1 CZ  1 ? 
ATOM   541  O OH  . TYR A 1 69  ? -6.652  -0.325  -28.801 0.330 24.590  0 71  TYR 1 OH  1 ? 
ATOM   542  N N   . PRO A 1 70  ? -5.657  2.352   -36.386 0.330 27.120  0 72  PRO 1 N   1 ? 
ATOM   543  C CA  . PRO A 1 70  ? -5.621  2.097   -37.826 0.330 27.600  0 72  PRO 1 CA  1 ? 
ATOM   544  C C   . PRO A 1 70  ? -6.655  1.024   -38.181 0.330 28.630  0 72  PRO 1 C   1 ? 
ATOM   545  O O   . PRO A 1 70  ? -7.105  0.338   -37.274 0.330 28.000  0 72  PRO 1 O   1 ? 
ATOM   546  C CB  . PRO A 1 70  ? -4.183  1.602   -38.052 0.330 27.850  0 72  PRO 1 CB  1 ? 
ATOM   547  C CG  . PRO A 1 70  ? -3.831  0.923   -36.753 0.330 28.330  0 72  PRO 1 CG  1 ? 
ATOM   548  C CD  . PRO A 1 70  ? -4.499  1.777   -35.689 0.330 27.420  0 72  PRO 1 CD  1 ? 
ATOM   549  N N   . ASP A 1 71  ? -7.005  0.901   -39.468 0.330 29.650  0 73  ASP 1 N   1 ? 
ATOM   550  C CA  . ASP A 1 71  ? -8.098  0.008   -39.946 0.330 30.500  0 73  ASP 1 CA  1 ? 
ATOM   551  C C   . ASP A 1 71  ? -7.735  -1.445  -39.637 0.330 28.880  0 73  ASP 1 C   1 ? 
ATOM   552  O O   . ASP A 1 71  ? -8.657  -2.257  -39.467 0.330 31.100  0 73  ASP 1 O   1 ? 
ATOM   553  C CB  . ASP A 1 71  ? -8.373  0.199   -41.439 0.330 33.370  0 73  ASP 1 CB  1 ? 
ATOM   554  C CG  . ASP A 1 71  ? -9.159  1.461   -41.773 0.330 34.580  0 73  ASP 1 CG  1 ? 
ATOM   555  O OD1 . ASP A 1 71  ? -10.083 1.797   -41.010 0.330 35.550  0 73  ASP 1 OD1 1 ? 
ATOM   556  O OD2 . ASP A 1 71  ? -8.852  2.094   -42.811 0.330 38.810  0 73  ASP 1 OD2 1 ? 
ATOM   557  N N   . ASN A 1 72  ? -6.444  -1.757  -39.525 0.330 29.900  0 74  ASN 1 N   1 ? 
ATOM   558  C CA  . ASN A 1 72  ? -5.955  -3.158  -39.442 0.330 29.630  0 74  ASN 1 CA  1 ? 
ATOM   559  C C   . ASN A 1 72  ? -5.736  -3.584  -37.987 0.330 29.100  0 74  ASN 1 C   1 ? 
ATOM   560  O O   . ASN A 1 72  ? -5.042  -4.602  -37.797 0.330 28.750  0 74  ASN 1 O   1 ? 
ATOM   561  C CB  . ASN A 1 72  ? -4.657  -3.352  -40.223 0.330 31.900  0 74  ASN 1 CB  1 ? 
ATOM   562  C CG  . ASN A 1 72  ? -3.481  -2.661  -39.577 0.330 33.330  0 74  ASN 1 CG  1 ? 
ATOM   563  O OD1 . ASN A 1 72  ? -3.662  -1.786  -38.735 0.330 32.940  0 74  ASN 1 OD1 1 ? 
ATOM   564  N ND2 . ASN A 1 72  ? -2.275  -3.046  -39.970 0.330 37.920  0 74  ASN 1 ND2 1 ? 
ATOM   565  N N   . ILE A 1 73  ? -6.275  -2.845  -37.011 0.330 26.910  0 75  ILE 1 N   1 ? 
ATOM   566  C CA  . ILE A 1 73  ? -6.360  -3.290  -35.583 0.330 26.300  0 75  ILE 1 CA  1 ? 
ATOM   567  C C   . ILE A 1 73  ? -7.810  -3.142  -35.105 0.330 26.670  0 75  ILE 1 C   1 ? 
ATOM   568  O O   . ILE A 1 73  ? -8.393  -2.059  -35.286 0.330 27.160  0 75  ILE 1 O   1 ? 
ATOM   569  C CB  . ILE A 1 73  ? -5.395  -2.503  -34.674 0.330 27.410  0 75  ILE 1 CB  1 ? 
ATOM   570  C CG1 . ILE A 1 73  ? -3.944  -2.542  -35.158 0.330 27.840  0 75  ILE 1 CG1 1 ? 
ATOM   571  C CG2 . ILE A 1 73  ? -5.508  -2.993  -33.237 0.330 28.200  0 75  ILE 1 CG2 1 ? 
ATOM   572  C CD1 . ILE A 1 73  ? -3.009  -1.646  -34.361 0.330 27.360  0 75  ILE 1 CD1 1 ? 
ATOM   573  N N   . GLN A 1 74  ? -8.361  -4.187  -34.485 0.330 25.240  0 76  GLN 1 N   1 ? 
ATOM   574  C CA  . GLN A 1 74  ? -9.727  -4.197  -33.901 0.330 24.670  0 76  GLN 1 CA  1 ? 
ATOM   575  C C   . GLN A 1 74  ? -9.803  -3.235  -32.701 0.330 25.270  0 76  GLN 1 C   1 ? 
ATOM   576  O O   . GLN A 1 74  ? -9.112  -3.474  -31.680 0.330 22.630  0 76  GLN 1 O   1 ? 
ATOM   577  C CB  . GLN A 1 74  ? -10.101 -5.621  -33.506 0.330 26.170  0 76  GLN 1 CB  1 ? 
ATOM   578  C CG  . GLN A 1 74  ? -11.213 -5.705  -32.474 0.330 26.830  0 76  GLN 1 CG  1 ? 
ATOM   579  C CD  . GLN A 1 74  ? -12.585 -5.394  -33.022 0.330 29.510  0 76  GLN 1 CD  1 ? 
ATOM   580  O OE1 . GLN A 1 74  ? -12.745 -4.773  -34.077 0.330 29.760  0 76  GLN 1 OE1 1 ? 
ATOM   581  N NE2 . GLN A 1 74  ? -13.598 -5.827  -32.288 0.330 28.990  0 76  GLN 1 NE2 1 ? 
ATOM   582  N N   . ASP A 1 75  ? -10.624 -2.187  -32.837 0.330 23.300  0 77  ASP 1 N   1 ? 
ATOM   583  C CA  . ASP A 1 75  ? -10.829 -1.121  -31.820 0.330 23.730  0 77  ASP 1 CA  1 ? 
ATOM   584  C C   . ASP A 1 75  ? -11.894 -1.582  -30.821 0.330 23.360  0 77  ASP 1 C   1 ? 
ATOM   585  O O   . ASP A 1 75  ? -13.099 -1.294  -31.034 0.330 24.950  0 77  ASP 1 O   1 ? 
ATOM   586  C CB  . ASP A 1 75  ? -11.232 0.191   -32.487 0.330 23.560  0 77  ASP 1 CB  1 ? 
ATOM   587  C CG  . ASP A 1 75  ? -11.221 1.380   -31.544 0.330 23.490  0 77  ASP 1 CG  1 ? 
ATOM   588  O OD1 . ASP A 1 75  ? -11.185 1.153   -30.324 0.330 22.640  0 77  ASP 1 OD1 1 ? 
ATOM   589  O OD2 . ASP A 1 75  ? -11.273 2.511   -32.048 0.330 23.800  0 77  ASP 1 OD2 1 ? 
ATOM   590  N N   . TYR A 1 76  ? -11.465 -2.309  -29.792 0.330 22.460  0 78  TYR 1 N   1 ? 
ATOM   591  C CA  . TYR A 1 76  ? -12.327 -2.846  -28.714 0.330 23.510  0 78  TYR 1 CA  1 ? 
ATOM   592  C C   . TYR A 1 76  ? -13.134 -1.703  -28.087 0.330 23.710  0 78  TYR 1 C   1 ? 
ATOM   593  O O   . TYR A 1 76  ? -14.330 -1.869  -27.787 0.330 25.000  0 78  TYR 1 O   1 ? 
ATOM   594  C CB  . TYR A 1 76  ? -11.431 -3.538  -27.687 0.330 24.290  0 78  TYR 1 CB  1 ? 
ATOM   595  C CG  . TYR A 1 76  ? -12.144 -4.335  -26.633 0.330 24.990  0 78  TYR 1 CG  1 ? 
ATOM   596  C CD1 . TYR A 1 76  ? -12.716 -5.558  -26.936 0.330 25.890  0 78  TYR 1 CD1 1 ? 
ATOM   597  C CD2 . TYR A 1 76  ? -12.202 -3.897  -25.320 0.330 24.890  0 78  TYR 1 CD2 1 ? 
ATOM   598  C CE1 . TYR A 1 76  ? -13.347 -6.316  -25.969 0.330 25.790  0 78  TYR 1 CE1 1 ? 
ATOM   599  C CE2 . TYR A 1 76  ? -12.820 -4.650  -24.337 0.330 25.150  0 78  TYR 1 CE2 1 ? 
ATOM   600  C CZ  . TYR A 1 76  ? -13.401 -5.861  -24.664 0.330 26.830  0 78  TYR 1 CZ  1 ? 
ATOM   601  O OH  . TYR A 1 76  ? -14.035 -6.611  -23.709 0.330 26.670  0 78  TYR 1 OH  1 ? 
ATOM   602  N N   . PHE A 1 77  ? -12.489 -0.551  -27.898 0.330 23.710  0 79  PHE 1 N   1 ? 
ATOM   603  C CA  . PHE A 1 77  ? -13.024 0.570   -27.082 0.330 23.520  0 79  PHE 1 CA  1 ? 
ATOM   604  C C   . PHE A 1 77  ? -14.204 1.200   -27.825 0.330 24.650  0 79  PHE 1 C   1 ? 
ATOM   605  O O   . PHE A 1 77  ? -15.312 1.222   -27.265 0.330 25.100  0 79  PHE 1 O   1 ? 
ATOM   606  C CB  . PHE A 1 77  ? -11.873 1.508   -26.702 0.330 23.040  0 79  PHE 1 CB  1 ? 
ATOM   607  C CG  . PHE A 1 77  ? -10.754 0.782   -25.997 0.330 22.790  0 79  PHE 1 CG  1 ? 
ATOM   608  C CD1 . PHE A 1 77  ? -10.942 0.283   -24.715 0.330 22.980  0 79  PHE 1 CD1 1 ? 
ATOM   609  C CD2 . PHE A 1 77  ? -9.550  0.530   -26.629 0.330 23.050  0 79  PHE 1 CD2 1 ? 
ATOM   610  C CE1 . PHE A 1 77  ? -9.938  -0.419  -24.074 0.330 22.910  0 79  PHE 1 CE1 1 ? 
ATOM   611  C CE2 . PHE A 1 77  ? -8.545  -0.174  -25.983 0.330 23.740  0 79  PHE 1 CE2 1 ? 
ATOM   612  C CZ  . PHE A 1 77  ? -8.741  -0.645  -24.708 0.330 23.850  0 79  PHE 1 CZ  1 ? 
ATOM   613  N N   . LYS A 1 78  ? -13.999 1.639   -29.069 0.330 25.830  0 80  LYS 1 N   1 ? 
ATOM   614  C CA  . LYS A 1 78  ? -15.050 2.328   -29.862 0.330 26.440  0 80  LYS 1 CA  1 ? 
ATOM   615  C C   . LYS A 1 78  ? -16.179 1.349   -30.213 0.330 27.920  0 80  LYS 1 C   1 ? 
ATOM   616  O O   . LYS A 1 78  ? -17.282 1.821   -30.524 0.330 29.450  0 80  LYS 1 O   1 ? 
ATOM   617  C CB  . LYS A 1 78  ? -14.450 2.953   -31.124 0.330 26.330  0 80  LYS 1 CB  1 ? 
ATOM   618  C CG  . LYS A 1 78  ? -13.525 4.132   -30.871 0.330 26.010  0 80  LYS 1 CG  1 ? 
ATOM   619  C CD  . LYS A 1 78  ? -13.146 4.887   -32.126 0.330 25.440  0 80  LYS 1 CD  1 ? 
ATOM   620  C CE  . LYS A 1 78  ? -12.140 5.992   -31.871 0.330 25.520  0 80  LYS 1 CE  1 ? 
ATOM   621  N NZ  . LYS A 1 78  ? -10.828 5.443   -31.449 0.330 24.750  0 80  LYS 1 NZ  1 ? 
ATOM   622  N N   . GLN A 1 79  ? -15.924 0.038   -30.174 0.330 28.950  0 81  GLN 1 N   1 ? 
ATOM   623  C CA  . GLN A 1 79  ? -16.956 -1.014  -30.412 0.330 29.590  0 81  GLN 1 CA  1 ? 
ATOM   624  C C   . GLN A 1 79  ? -17.733 -1.288  -29.119 0.330 28.130  0 81  GLN 1 C   1 ? 
ATOM   625  O O   . GLN A 1 79  ? -18.770 -1.957  -29.181 0.330 27.720  0 81  GLN 1 O   1 ? 
ATOM   626  C CB  . GLN A 1 79  ? -16.295 -2.303  -30.903 0.330 30.550  0 81  GLN 1 CB  1 ? 
ATOM   627  C CG  . GLN A 1 79  ? -15.657 -2.185  -32.273 0.330 33.030  0 81  GLN 1 CG  1 ? 
ATOM   628  C CD  . GLN A 1 79  ? -16.492 -2.884  -33.311 0.330 39.550  0 81  GLN 1 CD  1 ? 
ATOM   629  O OE1 . GLN A 1 79  ? -16.610 -4.118  -33.321 0.330 41.340  0 81  GLN 1 OE1 1 ? 
ATOM   630  N NE2 . GLN A 1 79  ? -17.089 -2.086  -34.186 0.330 40.790  0 81  GLN 1 NE2 1 ? 
ATOM   631  N N   . SER A 1 80  ? -17.252 -0.776  -27.987 0.330 26.930  0 82  SER 1 N   1 ? 
ATOM   632  C CA  . SER A 1 80  ? -17.835 -1.002  -26.638 0.330 28.430  0 82  SER 1 CA  1 ? 
ATOM   633  C C   . SER A 1 80  ? -19.094 -0.152  -26.433 0.330 27.570  0 82  SER 1 C   1 ? 
ATOM   634  O O   . SER A 1 80  ? -19.845 -0.449  -25.489 0.330 27.140  0 82  SER 1 O   1 ? 
ATOM   635  C CB  . SER A 1 80  ? -16.825 -0.703  -25.563 0.330 27.890  0 82  SER 1 CB  1 ? 
ATOM   636  O OG  . SER A 1 80  ? -15.755 -1.622  -25.640 0.330 31.350  0 82  SER 1 OG  1 ? 
ATOM   637  N N   . PHE A 1 81  ? -19.298 0.875   -27.260 0.330 27.510  0 83  PHE 1 N   1 ? 
ATOM   638  C CA  . PHE A 1 81  ? -20.360 1.891   -27.062 0.330 27.860  0 83  PHE 1 CA  1 ? 
ATOM   639  C C   . PHE A 1 81  ? -21.537 1.567   -27.972 0.330 30.270  0 83  PHE 1 C   1 ? 
ATOM   640  O O   . PHE A 1 81  ? -21.368 0.934   -29.007 0.330 30.290  0 83  PHE 1 O   1 ? 
ATOM   641  C CB  . PHE A 1 81  ? -19.789 3.295   -27.246 0.330 27.410  0 83  PHE 1 CB  1 ? 
ATOM   642  C CG  . PHE A 1 81  ? -18.849 3.671   -26.133 0.330 26.720  0 83  PHE 1 CG  1 ? 
ATOM   643  C CD1 . PHE A 1 81  ? -19.337 4.194   -24.949 0.330 26.780  0 83  PHE 1 CD1 1 ? 
ATOM   644  C CD2 . PHE A 1 81  ? -17.493 3.402   -26.227 0.330 27.640  0 83  PHE 1 CD2 1 ? 
ATOM   645  C CE1 . PHE A 1 81  ? -18.482 4.494   -23.904 0.330 27.210  0 83  PHE 1 CE1 1 ? 
ATOM   646  C CE2 . PHE A 1 81  ? -16.635 3.705   -25.181 0.330 26.520  0 83  PHE 1 CE2 1 ? 
ATOM   647  C CZ  . PHE A 1 81  ? -17.133 4.250   -24.021 0.330 28.690  0 83  PHE 1 CZ  1 ? 
ATOM   648  N N   . PRO A 1 82  ? -22.764 1.994   -27.608 0.330 30.840  0 84  PRO 1 N   1 ? 
ATOM   649  C CA  . PRO A 1 82  ? -22.968 2.938   -26.506 0.330 31.390  0 84  PRO 1 CA  1 ? 
ATOM   650  C C   . PRO A 1 82  ? -23.075 2.404   -25.065 0.330 28.570  0 84  PRO 1 C   1 ? 
ATOM   651  O O   . PRO A 1 82  ? -23.184 3.228   -24.166 0.330 29.620  0 84  PRO 1 O   1 ? 
ATOM   652  C CB  . PRO A 1 82  ? -24.322 3.573   -26.882 0.330 33.260  0 84  PRO 1 CB  1 ? 
ATOM   653  C CG  . PRO A 1 82  ? -25.070 2.479   -27.628 0.330 32.990  0 84  PRO 1 CG  1 ? 
ATOM   654  C CD  . PRO A 1 82  ? -24.010 1.639   -28.310 0.330 33.150  0 84  PRO 1 CD  1 ? 
ATOM   655  N N   . LYS A 1 83  ? -23.028 1.087   -24.859 0.330 26.110  0 85  LYS 1 N   1 ? 
ATOM   656  C CA  . LYS A 1 83  ? -23.194 0.457   -23.518 0.330 26.520  0 85  LYS 1 CA  1 ? 
ATOM   657  C C   . LYS A 1 83  ? -21.980 0.744   -22.626 0.330 25.900  0 85  LYS 1 C   1 ? 
ATOM   658  O O   . LYS A 1 83  ? -22.151 0.750   -21.399 0.330 27.310  0 85  LYS 1 O   1 ? 
ATOM   659  C CB  . LYS A 1 83  ? -23.398 -1.055  -23.630 0.330 27.270  0 85  LYS 1 CB  1 ? 
ATOM   660  C CG  . LYS A 1 83  ? -24.827 -1.489  -23.909 0.330 28.550  0 85  LYS 1 CG  1 ? 
ATOM   661  C CD  . LYS A 1 83  ? -25.088 -2.932  -23.564 0.330 30.380  0 85  LYS 1 CD  1 ? 
ATOM   662  C CE  . LYS A 1 83  ? -26.486 -3.376  -23.934 0.330 30.980  0 85  LYS 1 CE  1 ? 
ATOM   663  N NZ  . LYS A 1 83  ? -26.505 -4.815  -24.274 0.330 32.470  0 85  LYS 1 NZ  1 ? 
ATOM   664  N N   . GLY A 1 84  ? -20.804 0.949   -23.220 0.330 24.520  0 86  GLY 1 N   1 ? 
ATOM   665  C CA  . GLY A 1 84  ? -19.576 1.344   -22.505 0.330 23.330  0 86  GLY 1 CA  1 ? 
ATOM   666  C C   . GLY A 1 84  ? -18.747 0.169   -22.011 0.330 23.560  0 86  GLY 1 C   1 ? 
ATOM   667  O O   . GLY A 1 84  ? -18.997 -0.990  -22.418 0.330 22.560  0 86  GLY 1 O   1 ? 
ATOM   668  N N   . TYR A 1 85  ? -17.766 0.463   -21.157 0.330 22.840  0 87  TYR 1 N   1 ? 
ATOM   669  C CA  . TYR A 1 85  ? -16.754 -0.501  -20.657 0.330 22.040  0 87  TYR 1 CA  1 ? 
ATOM   670  C C   . TYR A 1 85  ? -16.177 0.012   -19.340 0.330 21.970  0 87  TYR 1 C   1 ? 
ATOM   671  O O   . TYR A 1 85  ? -16.354 1.198   -19.008 0.330 22.760  0 87  TYR 1 O   1 ? 
ATOM   672  C CB  . TYR A 1 85  ? -15.651 -0.742  -21.694 0.330 20.940  0 87  TYR 1 CB  1 ? 
ATOM   673  C CG  . TYR A 1 85  ? -14.597 0.331   -21.809 0.330 21.950  0 87  TYR 1 CG  1 ? 
ATOM   674  C CD1 . TYR A 1 85  ? -14.834 1.499   -22.517 0.330 22.360  0 87  TYR 1 CD1 1 ? 
ATOM   675  C CD2 . TYR A 1 85  ? -13.341 0.167   -21.245 0.330 21.830  0 87  TYR 1 CD2 1 ? 
ATOM   676  C CE1 . TYR A 1 85  ? -13.863 2.486   -22.635 0.330 23.350  0 87  TYR 1 CE1 1 ? 
ATOM   677  C CE2 . TYR A 1 85  ? -12.359 1.142   -21.357 0.330 21.710  0 87  TYR 1 CE2 1 ? 
ATOM   678  C CZ  . TYR A 1 85  ? -12.618 2.306   -22.056 0.330 23.070  0 87  TYR 1 CZ  1 ? 
ATOM   679  O OH  . TYR A 1 85  ? -11.655 3.272   -22.155 0.330 22.030  0 87  TYR 1 OH  1 ? 
ATOM   680  N N   . SER A 1 86  ? -15.521 -0.884  -18.610 0.330 21.720  0 88  SER 1 N   1 ? 
ATOM   681  C CA  . SER A 1 86  ? -14.796 -0.602  -17.347 0.330 22.850  0 88  SER 1 CA  1 ? 
ATOM   682  C C   . SER A 1 86  ? -13.326 -0.952  -17.561 0.330 22.790  0 88  SER 1 C   1 ? 
ATOM   683  O O   . SER A 1 86  ? -13.022 -1.706  -18.508 0.330 23.020  0 88  SER 1 O   1 ? 
ATOM   684  C CB  . SER A 1 86  ? -15.347 -1.396  -16.188 0.330 22.740  0 88  SER 1 CB  1 ? 
ATOM   685  O OG  . SER A 1 86  ? -16.700 -1.758  -16.410 0.330 24.150  0 88  SER 1 OG  1 ? 
ATOM   686  N N   . TRP A 1 87  ? -12.451 -0.399  -16.729 0.330 22.220  0 89  TRP 1 N   1 ? 
ATOM   687  C CA  . TRP A 1 87  ? -11.064 -0.891  -16.583 0.330 22.580  0 89  TRP 1 CA  1 ? 
ATOM   688  C C   . TRP A 1 87  ? -10.689 -0.864  -15.108 0.330 23.070  0 89  TRP 1 C   1 ? 
ATOM   689  O O   . TRP A 1 87  ? -11.264 -0.043  -14.340 0.330 22.440  0 89  TRP 1 O   1 ? 
ATOM   690  C CB  . TRP A 1 87  ? -10.086 -0.116  -17.469 0.330 22.430  0 89  TRP 1 CB  1 ? 
ATOM   691  C CG  . TRP A 1 87  ? -10.031 1.370   -17.266 0.330 22.720  0 89  TRP 1 CG  1 ? 
ATOM   692  C CD1 . TRP A 1 87  ? -10.526 2.324   -18.103 0.330 21.920  0 89  TRP 1 CD1 1 ? 
ATOM   693  C CD2 . TRP A 1 87  ? -9.340  2.077   -16.218 0.330 22.720  0 89  TRP 1 CD2 1 ? 
ATOM   694  N NE1 . TRP A 1 87  ? -10.228 3.573   -17.631 0.330 22.990  0 89  TRP 1 NE1 1 ? 
ATOM   695  C CE2 . TRP A 1 87  ? -9.508  3.455   -16.471 0.330 22.710  0 89  TRP 1 CE2 1 ? 
ATOM   696  C CE3 . TRP A 1 87  ? -8.634  1.682   -15.075 0.330 22.840  0 89  TRP 1 CE3 1 ? 
ATOM   697  C CZ2 . TRP A 1 87  ? -8.993  4.437   -15.630 0.330 22.840  0 89  TRP 1 CZ2 1 ? 
ATOM   698  C CZ3 . TRP A 1 87  ? -8.127  2.654   -14.242 0.330 23.290  0 89  TRP 1 CZ3 1 ? 
ATOM   699  C CH2 . TRP A 1 87  ? -8.308  4.013   -14.513 0.330 23.230  0 89  TRP 1 CH2 1 ? 
ATOM   700  N N   . GLU A 1 88  ? -9.793  -1.771  -14.731 0.330 24.270  0 90  GLU 1 N   1 ? 
ATOM   701  C CA  . GLU A 1 88  ? -9.149  -1.818  -13.397 0.330 24.580  0 90  GLU 1 CA  1 ? 
ATOM   702  C C   . GLU A 1 88  ? -7.641  -1.794  -13.611 0.330 23.160  0 90  GLU 1 C   1 ? 
ATOM   703  O O   . GLU A 1 88  ? -7.159  -2.466  -14.536 0.330 23.450  0 90  GLU 1 O   1 ? 
ATOM   704  C CB  . GLU A 1 88  ? -9.548  -3.085  -12.642 0.330 27.230  0 90  GLU 1 CB  1 ? 
ATOM   705  C CG  . GLU A 1 88  ? -11.016 -3.133  -12.290 0.330 31.280  0 90  GLU 1 CG  1 ? 
ATOM   706  C CD  . GLU A 1 88  ? -11.405 -4.389  -11.536 0.330 34.830  0 90  GLU 1 CD  1 ? 
ATOM   707  O OE1 . GLU A 1 88  ? -10.488 -5.221  -11.258 0.330 34.440  0 90  GLU 1 OE1 1 ? 
ATOM   708  O OE2 . GLU A 1 88  ? -12.613 -4.542  -11.245 0.330 36.840  0 90  GLU 1 OE2 1 ? 
ATOM   709  N N   . ARG A 1 89  ? -6.922  -1.022  -12.808 0.330 22.800  0 91  ARG 1 N   1 ? 
ATOM   710  C CA  . ARG A 1 89  ? -5.463  -0.841  -12.989 0.330 21.750  0 91  ARG 1 CA  1 ? 
ATOM   711  C C   . ARG A 1 89  ? -4.775  -1.025  -11.638 0.330 22.270  0 91  ARG 1 C   1 ? 
ATOM   712  O O   . ARG A 1 89  ? -5.327  -0.554  -10.626 0.330 21.880  0 91  ARG 1 O   1 ? 
ATOM   713  C CB  . ARG A 1 89  ? -5.185  0.547   -13.566 0.330 22.080  0 91  ARG 1 CB  1 ? 
ATOM   714  C CG  . ARG A 1 89  ? -3.717  0.837   -13.820 0.330 23.160  0 91  ARG 1 CG  1 ? 
ATOM   715  C CD  . ARG A 1 89  ? -3.539  2.111   -14.634 0.330 24.400  0 91  ARG 1 CD  1 ? 
ATOM   716  N NE  . ARG A 1 89  ? -4.387  2.104   -15.820 0.330 24.310  0 91  ARG 1 NE  1 ? 
ATOM   717  C CZ  . ARG A 1 89  ? -4.815  3.188   -16.457 0.330 25.120  0 91  ARG 1 CZ  1 ? 
ATOM   718  N NH1 . ARG A 1 89  ? -4.437  4.391   -16.053 0.330 25.100  0 91  ARG 1 NH1 1 ? 
ATOM   719  N NH2 . ARG A 1 89  ? -5.618  3.061   -17.499 0.330 23.420  0 91  ARG 1 NH2 1 ? 
ATOM   720  N N   . SER A 1 90  ? -3.629  -1.705  -11.616 0.330 22.680  0 92  SER 1 N   1 ? 
ATOM   721  C CA  . SER A 1 90  ? -2.712  -1.679  -10.452 0.330 22.020  0 92  SER 1 CA  1 ? 
ATOM   722  C C   . SER A 1 90  ? -1.408  -1.003  -10.891 0.330 22.580  0 92  SER 1 C   1 ? 
ATOM   723  O O   . SER A 1 90  ? -0.827  -1.424  -11.907 0.330 23.220  0 92  SER 1 O   1 ? 
ATOM   724  C CB  . SER A 1 90  ? -2.507  -3.052  -9.860  0.330 21.790  0 92  SER 1 CB  1 ? 
ATOM   725  O OG  . SER A 1 90  ? -1.167  -3.473  -10.026 0.330 21.390  0 92  SER 1 OG  1 ? 
ATOM   726  N N   . LEU A 1 91  ? -1.041  0.071   -10.195 0.330 21.570  0 93  LEU 1 N   1 ? 
ATOM   727  C CA  . LEU A 1 91  ? 0.252   0.792   -10.330 0.330 21.910  0 93  LEU 1 CA  1 ? 
ATOM   728  C C   . LEU A 1 91  ? 1.180   0.297   -9.221  0.330 21.970  0 93  LEU 1 C   1 ? 
ATOM   729  O O   . LEU A 1 91  ? 0.703   0.150   -8.074  0.330 21.220  0 93  LEU 1 O   1 ? 
ATOM   730  C CB  . LEU A 1 91  ? 0.006   2.300   -10.230 0.330 22.280  0 93  LEU 1 CB  1 ? 
ATOM   731  C CG  . LEU A 1 91  ? -0.955  2.867   -11.272 0.330 24.230  0 93  LEU 1 CG  1 ? 
ATOM   732  C CD1 . LEU A 1 91  ? -2.405  2.675   -10.842 0.330 25.140  0 93  LEU 1 CD1 1 ? 
ATOM   733  C CD2 . LEU A 1 91  ? -0.673  4.337   -11.533 0.330 24.430  0 93  LEU 1 CD2 1 ? 
ATOM   734  N N   . THR A 1 92  ? 2.424   -0.017  -9.575  0.330 21.970  0 94  THR 1 N   1 ? 
ATOM   735  C CA  . THR A 1 92  ? 3.486   -0.453  -8.639  0.330 23.710  0 94  THR 1 CA  1 ? 
ATOM   736  C C   . THR A 1 92  ? 4.705   0.441   -8.848  0.330 22.920  0 94  THR 1 C   1 ? 
ATOM   737  O O   . THR A 1 92  ? 5.272   0.400   -9.939  0.330 22.840  0 94  THR 1 O   1 ? 
ATOM   738  C CB  . THR A 1 92  ? 3.805   -1.941  -8.824  0.330 24.770  0 94  THR 1 CB  1 ? 
ATOM   739  O OG1 . THR A 1 92  ? 2.578   -2.654  -8.674  0.330 25.290  0 94  THR 1 OG1 1 ? 
ATOM   740  C CG2 . THR A 1 92  ? 4.819   -2.448  -7.826  0.330 26.730  0 94  THR 1 CG2 1 ? 
ATOM   741  N N   . PHE A 1 93  ? 5.072   1.213   -7.825  0.330 24.080  0 95  PHE 1 N   1 ? 
ATOM   742  C CA  . PHE A 1 93  ? 6.201   2.177   -7.852  0.330 24.550  0 95  PHE 1 CA  1 ? 
ATOM   743  C C   . PHE A 1 93  ? 7.425   1.514   -7.215  0.330 25.600  0 95  PHE 1 C   1 ? 
ATOM   744  O O   . PHE A 1 93  ? 7.256   0.610   -6.377  0.330 25.290  0 95  PHE 1 O   1 ? 
ATOM   745  C CB  . PHE A 1 93  ? 5.800   3.475   -7.157  0.330 24.970  0 95  PHE 1 CB  1 ? 
ATOM   746  C CG  . PHE A 1 93  ? 4.715   4.245   -7.864  0.330 24.380  0 95  PHE 1 CG  1 ? 
ATOM   747  C CD1 . PHE A 1 93  ? 5.031   5.189   -8.825  0.330 24.830  0 95  PHE 1 CD1 1 ? 
ATOM   748  C CD2 . PHE A 1 93  ? 3.382   4.035   -7.558  0.330 25.410  0 95  PHE 1 CD2 1 ? 
ATOM   749  C CE1 . PHE A 1 93  ? 4.036   5.911   -9.463  0.330 23.970  0 95  PHE 1 CE1 1 ? 
ATOM   750  C CE2 . PHE A 1 93  ? 2.387   4.757   -8.198  0.330 25.950  0 95  PHE 1 CE2 1 ? 
ATOM   751  C CZ  . PHE A 1 93  ? 2.719   5.695   -9.146  0.330 26.190  0 95  PHE 1 CZ  1 ? 
ATOM   752  N N   . GLU A 1 94  ? 8.618   1.944   -7.624  0.330 25.920  0 96  GLU 1 N   1 ? 
ATOM   753  C CA  . GLU A 1 94  ? 9.900   1.268   -7.295  0.330 27.150  0 96  GLU 1 CA  1 ? 
ATOM   754  C C   . GLU A 1 94  ? 10.144  1.252   -5.779  0.330 26.940  0 96  GLU 1 C   1 ? 
ATOM   755  O O   . GLU A 1 94  ? 10.933  0.399   -5.337  0.330 29.170  0 96  GLU 1 O   1 ? 
ATOM   756  C CB  . GLU A 1 94  ? 11.051  1.963   -8.024  0.330 26.680  0 96  GLU 1 CB  1 ? 
ATOM   757  C CG  . GLU A 1 94  ? 11.243  3.415   -7.622  0.330 26.960  0 96  GLU 1 CG  1 ? 
ATOM   758  C CD  . GLU A 1 94  ? 12.434  4.079   -8.294  0.330 26.150  0 96  GLU 1 CD  1 ? 
ATOM   759  O OE1 . GLU A 1 94  ? 13.173  4.818   -7.601  0.330 26.980  0 96  GLU 1 OE1 1 ? 
ATOM   760  O OE2 . GLU A 1 94  ? 12.640  3.833   -9.503  0.330 24.240  0 96  GLU 1 OE2 1 ? 
ATOM   761  N N   . ASP A 1 95  ? 9.507   2.153   -5.021  0.330 27.820  0 97  ASP 1 N   1 ? 
ATOM   762  C CA  . ASP A 1 95  ? 9.779   2.362   -3.572  0.330 26.900  0 97  ASP 1 CA  1 ? 
ATOM   763  C C   . ASP A 1 95  ? 8.621   1.834   -2.713  0.330 28.180  0 97  ASP 1 C   1 ? 
ATOM   764  O O   . ASP A 1 95  ? 8.476   2.317   -1.565  0.330 28.270  0 97  ASP 1 O   1 ? 
ATOM   765  C CB  . ASP A 1 95  ? 10.036  3.839   -3.268  0.330 27.210  0 97  ASP 1 CB  1 ? 
ATOM   766  C CG  . ASP A 1 95  ? 8.812   4.735   -3.383  0.330 26.410  0 97  ASP 1 CG  1 ? 
ATOM   767  O OD1 . ASP A 1 95  ? 7.768   4.259   -3.874  0.330 26.590  0 97  ASP 1 OD1 1 ? 
ATOM   768  O OD2 . ASP A 1 95  ? 8.910   5.904   -2.960  0.330 27.280  0 97  ASP 1 OD2 1 ? 
ATOM   769  N N   . GLY A 1 96  ? 7.822   0.898   -3.238  0.330 27.620  0 98  GLY 1 N   1 ? 
ATOM   770  C CA  . GLY A 1 96  ? 6.794   0.174   -2.464  0.330 28.120  0 98  GLY 1 CA  1 ? 
ATOM   771  C C   . GLY A 1 96  ? 5.403   0.772   -2.599  0.330 28.000  0 98  GLY 1 C   1 ? 
ATOM   772  O O   . GLY A 1 96  ? 4.423   0.076   -2.270  0.330 27.910  0 98  GLY 1 O   1 ? 
ATOM   773  N N   . GLY A 1 97  ? 5.302   2.023   -3.048  0.330 27.830  0 99  GLY 1 N   1 ? 
ATOM   774  C CA  . GLY A 1 97  ? 4.006   2.696   -3.266  0.330 26.700  0 99  GLY 1 CA  1 ? 
ATOM   775  C C   . GLY A 1 97  ? 3.171   1.897   -4.251  0.330 27.570  0 99  GLY 1 C   1 ? 
ATOM   776  O O   . GLY A 1 97  ? 3.671   1.621   -5.354  0.330 26.860  0 99  GLY 1 O   1 ? 
ATOM   777  N N   . ILE A 1 98  ? 1.962   1.497   -3.858  0.330 27.810  0 100 ILE 1 N   1 ? 
ATOM   778  C CA  . ILE A 1 98  ? 1.060   0.670   -4.707  0.330 30.060  0 100 ILE 1 CA  1 ? 
ATOM   779  C C   . ILE A 1 98  ? -0.314  1.340   -4.717  0.330 29.350  0 100 ILE 1 C   1 ? 
ATOM   780  O O   . ILE A 1 98  ? -0.685  1.930   -3.687  0.330 28.780  0 100 ILE 1 O   1 ? 
ATOM   781  C CB  . ILE A 1 98  ? 0.990   -0.779  -4.183  0.330 32.960  0 100 ILE 1 CB  1 ? 
ATOM   782  C CG1 . ILE A 1 98  ? -0.087  -1.589  -4.903  0.330 37.390  0 100 ILE 1 CG1 1 ? 
ATOM   783  C CG2 . ILE A 1 98  ? 0.793   -0.804  -2.679  0.330 34.130  0 100 ILE 1 CG2 1 ? 
ATOM   784  C CD1 . ILE A 1 98  ? 0.373   -2.182  -6.212  0.330 40.270  0 100 ILE 1 CD1 1 ? 
ATOM   785  N N   . CYS A 1 99  ? -1.055  1.260   -5.823  0.330 26.900  0 101 CYS 1 N   1 ? 
ATOM   786  C CA  . CYS A 1 99  ? -2.510  1.539   -5.763  0.330 26.460  0 101 CYS 1 CA  1 ? 
ATOM   787  C C   . CYS A 1 99  ? -3.284  0.874   -6.890  0.330 25.520  0 101 CYS 1 C   1 ? 
ATOM   788  O O   . CYS A 1 99  ? -2.679  0.268   -7.786  0.330 25.340  0 101 CYS 1 O   1 ? 
ATOM   789  C CB  . CYS A 1 99  ? -2.830  3.022   -5.743  0.330 27.090  0 101 CYS 1 CB  1 ? 
ATOM   790  S SG  . CYS A 1 99  ? -1.638  4.005   -4.802  0.330 31.490  0 101 CYS 1 SG  1 ? 
ATOM   791  N N   . ASN A 1 100 ? -4.601  0.973   -6.748  0.330 25.990  0 102 ASN 1 N   1 ? 
ATOM   792  C CA  . ASN A 1 100 ? -5.645  0.326   -7.573  0.330 26.510  0 102 ASN 1 CA  1 ? 
ATOM   793  C C   . ASN A 1 100 ? -6.613  1.427   -7.998  0.330 24.630  0 102 ASN 1 C   1 ? 
ATOM   794  O O   . ASN A 1 100 ? -7.156  2.109   -7.122  0.330 24.230  0 102 ASN 1 O   1 ? 
ATOM   795  C CB  . ASN A 1 100 ? -6.370  -0.775  -6.795  0.330 29.940  0 102 ASN 1 CB  1 ? 
ATOM   796  C CG  . ASN A 1 100 ? -5.415  -1.801  -6.223  0.330 33.510  0 102 ASN 1 CG  1 ? 
ATOM   797  O OD1 . ASN A 1 100 ? -4.680  -2.451  -6.967  0.330 37.270  0 102 ASN 1 OD1 1 ? 
ATOM   798  N ND2 . ASN A 1 100 ? -5.418  -1.950  -4.907  0.330 35.380  0 102 ASN 1 ND2 1 ? 
ATOM   799  N N   . ALA A 1 101 ? -6.764  1.623   -9.299  0.330 23.440  0 103 ALA 1 N   1 ? 
ATOM   800  C CA  . ALA A 1 101 ? -7.712  2.583   -9.899  0.330 23.140  0 103 ALA 1 CA  1 ? 
ATOM   801  C C   . ALA A 1 101 ? -8.713  1.817   -10.772 0.330 23.930  0 103 ALA 1 C   1 ? 
ATOM   802  O O   . ALA A 1 101 ? -8.343  0.795   -11.395 0.330 24.050  0 103 ALA 1 O   1 ? 
ATOM   803  C CB  . ALA A 1 101 ? -6.956  3.625   -10.677 0.330 23.120  0 103 ALA 1 CB  1 ? 
ATOM   804  N N   . ARG A 1 102 ? -9.952  2.285   -10.803 0.330 23.400  0 104 ARG 1 N   1 ? 
ATOM   805  C CA  . ARG A 1 102 ? -10.988 1.728   -11.701 0.330 24.350  0 104 ARG 1 CA  1 ? 
ATOM   806  C C   . ARG A 1 102 ? -11.809 2.884   -12.282 0.330 23.110  0 104 ARG 1 C   1 ? 
ATOM   807  O O   . ARG A 1 102 ? -11.973 3.921   -11.612 0.330 22.480  0 104 ARG 1 O   1 ? 
ATOM   808  C CB  . ARG A 1 102 ? -11.853 0.704   -10.962 0.330 26.030  0 104 ARG 1 CB  1 ? 
ATOM   809  C CG  . ARG A 1 102 ? -12.449 1.205   -9.660  0.330 29.630  0 104 ARG 1 CG  1 ? 
ATOM   810  C CD  . ARG A 1 102 ? -13.076 0.075   -8.858  0.330 33.360  0 104 ARG 1 CD  1 ? 
ATOM   811  N NE  . ARG A 1 102 ? -13.969 0.534   -7.792  0.330 36.250  0 104 ARG 1 NE  1 ? 
ATOM   812  C CZ  . ARG A 1 102 ? -13.646 0.548   -6.495  0.330 38.640  0 104 ARG 1 CZ  1 ? 
ATOM   813  N NH1 . ARG A 1 102 ? -14.513 0.979   -5.593  0.330 38.240  0 104 ARG 1 NH1 1 ? 
ATOM   814  N NH2 . ARG A 1 102 ? -12.452 0.135   -6.108  0.330 37.860  0 104 ARG 1 NH2 1 ? 
ATOM   815  N N   . ASN A 1 103 ? -12.288 2.698   -13.505 0.330 21.830  0 105 ASN 1 N   1 ? 
ATOM   816  C CA  . ASN A 1 103 ? -13.190 3.639   -14.209 0.330 21.970  0 105 ASN 1 CA  1 ? 
ATOM   817  C C   . ASN A 1 103 ? -14.316 2.831   -14.847 0.330 22.270  0 105 ASN 1 C   1 ? 
ATOM   818  O O   . ASN A 1 103 ? -14.011 1.875   -15.583 0.330 22.790  0 105 ASN 1 O   1 ? 
ATOM   819  C CB  . ASN A 1 103 ? -12.440 4.460   -15.253 0.330 21.870  0 105 ASN 1 CB  1 ? 
ATOM   820  C CG  . ASN A 1 103 ? -13.224 5.672   -15.695 0.330 22.570  0 105 ASN 1 CG  1 ? 
ATOM   821  O OD1 . ASN A 1 103 ? -14.322 5.910   -15.188 0.330 23.680  0 105 ASN 1 OD1 1 ? 
ATOM   822  N ND2 . ASN A 1 103 ? -12.678 6.432   -16.637 0.330 23.490  0 105 ASN 1 ND2 1 ? 
ATOM   823  N N   . ASP A 1 104 ? -15.562 3.186   -14.541 0.330 22.300  0 106 ASP 1 N   1 ? 
ATOM   824  C CA  . ASP A 1 104 ? -16.765 2.689   -15.247 0.330 23.340  0 106 ASP 1 CA  1 ? 
ATOM   825  C C   . ASP A 1 104 ? -17.195 3.807   -16.201 0.330 23.020  0 106 ASP 1 C   1 ? 
ATOM   826  O O   . ASP A 1 104 ? -17.546 4.895   -15.708 0.330 22.570  0 106 ASP 1 O   1 ? 
ATOM   827  C CB  . ASP A 1 104 ? -17.867 2.286   -14.260 0.330 24.630  0 106 ASP 1 CB  1 ? 
ATOM   828  C CG  . ASP A 1 104 ? -17.385 1.447   -13.082 0.330 26.220  0 106 ASP 1 CG  1 ? 
ATOM   829  O OD1 . ASP A 1 104 ? -16.598 0.491   -13.299 0.330 25.290  0 106 ASP 1 OD1 1 ? 
ATOM   830  O OD2 . ASP A 1 104 ? -17.810 1.754   -11.940 0.330 29.400  0 106 ASP 1 OD2 1 ? 
ATOM   831  N N   . ILE A 1 105 ? -17.103 3.567   -17.509 0.330 22.070  0 107 ILE 1 N   1 ? 
ATOM   832  C CA  . ILE A 1 105 ? -17.368 4.592   -18.555 0.330 22.350  0 107 ILE 1 CA  1 ? 
ATOM   833  C C   . ILE A 1 105 ? -18.711 4.294   -19.225 0.330 23.270  0 107 ILE 1 C   1 ? 
ATOM   834  O O   . ILE A 1 105 ? -18.929 3.142   -19.650 0.330 23.790  0 107 ILE 1 O   1 ? 
ATOM   835  C CB  . ILE A 1 105 ? -16.216 4.657   -19.568 0.330 22.100  0 107 ILE 1 CB  1 ? 
ATOM   836  C CG1 . ILE A 1 105 ? -14.865 4.807   -18.866 0.330 22.490  0 107 ILE 1 CG1 1 ? 
ATOM   837  C CG2 . ILE A 1 105 ? -16.460 5.769   -20.577 0.330 22.460  0 107 ILE 1 CG2 1 ? 
ATOM   838  C CD1 . ILE A 1 105 ? -13.728 5.098   -19.802 0.330 22.760  0 107 ILE 1 CD1 1 ? 
ATOM   839  N N   . THR A 1 106 ? -19.581 5.299   -19.280 0.330 23.290  0 108 THR 1 N   1 ? 
ATOM   840  C CA  . THR A 1 106 ? -20.920 5.247   -19.920 0.330 24.410  0 108 THR 1 CA  1 ? 
ATOM   841  C C   . THR A 1 106 ? -21.004 6.393   -20.933 0.330 26.050  0 108 THR 1 C   1 ? 
ATOM   842  O O   . THR A 1 106 ? -20.171 7.316   -20.870 0.330 24.240  0 108 THR 1 O   1 ? 
ATOM   843  C CB  . THR A 1 106 ? -22.041 5.309   -18.872 0.330 25.650  0 108 THR 1 CB  1 ? 
ATOM   844  O OG1 . THR A 1 106 ? -21.799 6.432   -18.020 0.330 25.710  0 108 THR 1 OG1 1 ? 
ATOM   845  C CG2 . THR A 1 106 ? -22.132 4.062   -18.015 0.330 26.180  0 108 THR 1 CG2 1 ? 
ATOM   846  N N   . MET A 1 107 ? -21.958 6.315   -21.851 0.330 25.720  0 109 MET 1 N   1 ? 
ATOM   847  C CA  . MET A 1 107 ? -22.201 7.369   -22.858 0.330 27.140  0 109 MET 1 CA  1 ? 
ATOM   848  C C   . MET A 1 107 ? -23.664 7.795   -22.719 0.330 26.660  0 109 MET 1 C   1 ? 
ATOM   849  O O   . MET A 1 107 ? -24.504 6.926   -22.409 0.330 25.540  0 109 MET 1 O   1 ? 
ATOM   850  C CB  . MET A 1 107 ? -21.918 6.849   -24.275 0.330 28.380  0 109 MET 1 CB  1 ? 
ATOM   851  C CG  . MET A 1 107 ? -21.628 7.941   -25.286 0.330 29.660  0 109 MET 1 CG  1 ? 
ATOM   852  S SD  . MET A 1 107 ? -21.428 7.305   -26.977 0.330 32.030  0 109 MET 1 SD  1 ? 
ATOM   853  C CE  . MET A 1 107 ? -23.118 6.835   -27.325 0.330 31.940  0 109 MET 1 CE  1 ? 
ATOM   854  N N   . GLU A 1 108 ? -23.922 9.095   -22.870 0.330 26.630  0 110 GLU 1 N   1 ? 
ATOM   855  C CA  . GLU A 1 108 ? -25.276 9.691   -22.991 0.330 26.720  0 110 GLU 1 CA  1 ? 
ATOM   856  C C   . GLU A 1 108 ? -25.193 10.800  -24.039 0.330 26.710  0 110 GLU 1 C   1 ? 
ATOM   857  O O   . GLU A 1 108 ? -24.577 11.836  -23.756 0.330 26.620  0 110 GLU 1 O   1 ? 
ATOM   858  C CB  . GLU A 1 108 ? -25.758 10.236  -21.643 0.330 28.040  0 110 GLU 1 CB  1 ? 
ATOM   859  C CG  . GLU A 1 108 ? -25.955 9.167   -20.587 0.330 27.530  0 110 GLU 1 CG  1 ? 
ATOM   860  C CD  . GLU A 1 108 ? -26.983 8.118   -20.974 0.330 29.470  0 110 GLU 1 CD  1 ? 
ATOM   861  O OE1 . GLU A 1 108 ? -27.247 7.213   -20.152 0.330 27.840  0 110 GLU 1 OE1 1 ? 
ATOM   862  O OE2 . GLU A 1 108 ? -27.506 8.206   -22.107 0.330 30.860  0 110 GLU 1 OE2 1 ? 
ATOM   863  N N   . GLY A 1 109 ? -25.784 10.579  -25.210 0.330 27.420  0 111 GLY 1 N   1 ? 
ATOM   864  C CA  . GLY A 1 109 ? -25.709 11.525  -26.337 0.330 28.000  0 111 GLY 1 CA  1 ? 
ATOM   865  C C   . GLY A 1 109 ? -24.267 11.774  -26.745 0.330 28.130  0 111 GLY 1 C   1 ? 
ATOM   866  O O   . GLY A 1 109 ? -23.606 10.836  -27.200 0.330 29.490  0 111 GLY 1 O   1 ? 
ATOM   867  N N   . ASP A 1 110 ? -23.783 12.998  -26.559 0.330 28.110  0 112 ASP 1 N   1 ? 
ATOM   868  C CA  . ASP A 1 110 ? -22.445 13.435  -27.024 0.330 29.430  0 112 ASP 1 CA  1 ? 
ATOM   869  C C   . ASP A 1 110 ? -21.463 13.468  -25.848 0.330 26.190  0 112 ASP 1 C   1 ? 
ATOM   870  O O   . ASP A 1 110 ? -20.470 14.198  -25.961 0.330 26.800  0 112 ASP 1 O   1 ? 
ATOM   871  C CB  . ASP A 1 110 ? -22.540 14.828  -27.646 0.330 30.520  0 112 ASP 1 CB  1 ? 
ATOM   872  C CG  . ASP A 1 110 ? -22.922 15.891  -26.634 0.330 32.440  0 112 ASP 1 CG  1 ? 
ATOM   873  O OD1 . ASP A 1 110 ? -23.418 15.519  -25.543 0.330 32.200  0 112 ASP 1 OD1 1 ? 
ATOM   874  O OD2 . ASP A 1 110 ? -22.698 17.088  -26.928 0.330 34.700  0 112 ASP 1 OD2 1 ? 
ATOM   875  N N   . THR A 1 111 ? -21.731 12.744  -24.754 0.330 25.400  0 113 THR 1 N   1 ? 
ATOM   876  C CA  . THR A 1 111 ? -20.938 12.853  -23.499 0.330 24.150  0 113 THR 1 CA  1 ? 
ATOM   877  C C   . THR A 1 111 ? -20.542 11.477  -22.947 0.330 23.710  0 113 THR 1 C   1 ? 
ATOM   878  O O   . THR A 1 111 ? -21.425 10.626  -22.761 0.330 23.420  0 113 THR 1 O   1 ? 
ATOM   879  C CB  . THR A 1 111 ? -21.690 13.672  -22.449 0.330 24.320  0 113 THR 1 CB  1 ? 
ATOM   880  O OG1 . THR A 1 111 ? -21.876 14.974  -22.996 0.330 23.860  0 113 THR 1 OG1 1 ? 
ATOM   881  C CG2 . THR A 1 111 ? -20.946 13.778  -21.139 0.330 24.990  0 113 THR 1 CG2 1 ? 
ATOM   882  N N   . PHE A 1 112 ? -19.248 11.289  -22.671 0.330 23.990  0 114 PHE 1 N   1 ? 
ATOM   883  C CA  . PHE A 1 112 ? -18.705 10.174  -21.852 0.330 22.970  0 114 PHE 1 CA  1 ? 
ATOM   884  C C   . PHE A 1 112 ? -18.740 10.567  -20.372 0.330 22.020  0 114 PHE 1 C   1 ? 
ATOM   885  O O   . PHE A 1 112 ? -18.115 11.576  -20.009 0.330 22.820  0 114 PHE 1 O   1 ? 
ATOM   886  C CB  . PHE A 1 112 ? -17.265 9.844   -22.237 0.330 23.040  0 114 PHE 1 CB  1 ? 
ATOM   887  C CG  . PHE A 1 112 ? -17.088 9.311   -23.633 0.330 23.280  0 114 PHE 1 CG  1 ? 
ATOM   888  C CD1 . PHE A 1 112 ? -17.627 8.091   -23.995 0.330 23.860  0 114 PHE 1 CD1 1 ? 
ATOM   889  C CD2 . PHE A 1 112 ? -16.385 10.032  -24.580 0.330 23.920  0 114 PHE 1 CD2 1 ? 
ATOM   890  C CE1 . PHE A 1 112 ? -17.463 7.597   -25.280 0.330 23.610  0 114 PHE 1 CE1 1 ? 
ATOM   891  C CE2 . PHE A 1 112 ? -16.219 9.534   -25.864 0.330 25.080  0 114 PHE 1 CE2 1 ? 
ATOM   892  C CZ  . PHE A 1 112 ? -16.751 8.314   -26.206 0.330 24.090  0 114 PHE 1 CZ  1 ? 
ATOM   893  N N   . TYR A 1 113 ? -19.420 9.771   -19.549 0.330 22.050  0 115 TYR 1 N   1 ? 
ATOM   894  C CA  . TYR A 1 113 ? -19.450 9.901   -18.071 0.330 22.280  0 115 TYR 1 CA  1 ? 
ATOM   895  C C   . TYR A 1 113 ? -18.468 8.892   -17.473 0.330 21.380  0 115 TYR 1 C   1 ? 
ATOM   896  O O   . TYR A 1 113 ? -18.451 7.727   -17.914 0.330 21.730  0 115 TYR 1 O   1 ? 
ATOM   897  C CB  . TYR A 1 113 ? -20.873 9.711   -17.544 0.330 23.000  0 115 TYR 1 CB  1 ? 
ATOM   898  C CG  . TYR A 1 113 ? -21.781 10.883  -17.809 0.330 23.370  0 115 TYR 1 CG  1 ? 
ATOM   899  C CD1 . TYR A 1 113 ? -22.523 10.968  -18.975 0.330 24.210  0 115 TYR 1 CD1 1 ? 
ATOM   900  C CD2 . TYR A 1 113 ? -21.858 11.936  -16.914 0.330 24.420  0 115 TYR 1 CD2 1 ? 
ATOM   901  C CE1 . TYR A 1 113 ? -23.339 12.058  -19.237 0.330 25.230  0 115 TYR 1 CE1 1 ? 
ATOM   902  C CE2 . TYR A 1 113 ? -22.677 13.029  -17.155 0.330 24.380  0 115 TYR 1 CE2 1 ? 
ATOM   903  C CZ  . TYR A 1 113 ? -23.409 13.095  -18.324 0.330 24.890  0 115 TYR 1 CZ  1 ? 
ATOM   904  O OH  . TYR A 1 113 ? -24.222 14.165  -18.557 0.330 26.750  0 115 TYR 1 OH  1 ? 
ATOM   905  N N   . ASN A 1 114 ? -17.654 9.349   -16.523 0.330 20.590  0 116 ASN 1 N   1 ? 
ATOM   906  C CA  . ASN A 1 114 ? -16.566 8.548   -15.913 0.330 19.930  0 116 ASN 1 CA  1 ? 
ATOM   907  C C   . ASN A 1 114 ? -16.761 8.520   -14.401 0.330 19.220  0 116 ASN 1 C   1 ? 
ATOM   908  O O   . ASN A 1 114 ? -16.678 9.587   -13.770 0.330 19.190  0 116 ASN 1 O   1 ? 
ATOM   909  C CB  . ASN A 1 114 ? -15.183 9.107   -16.256 0.330 20.430  0 116 ASN 1 CB  1 ? 
ATOM   910  C CG  . ASN A 1 114 ? -14.912 9.185   -17.743 0.330 20.330  0 116 ASN 1 CG  1 ? 
ATOM   911  O OD1 . ASN A 1 114 ? -14.081 8.447   -18.254 0.330 20.940  0 116 ASN 1 OD1 1 ? 
ATOM   912  N ND2 . ASN A 1 114 ? -15.569 10.104  -18.431 0.330 19.840  0 116 ASN 1 ND2 1 ? 
ATOM   913  N N   . LYS A 1 115 ? -16.975 7.330   -13.847 0.330 18.800  0 117 LYS 1 N   1 ? 
ATOM   914  C CA  . LYS A 1 115 ? -17.049 7.110   -12.385 0.330 19.250  0 117 LYS 1 CA  1 ? 
ATOM   915  C C   . LYS A 1 115 ? -15.718 6.496   -11.950 0.330 19.380  0 117 LYS 1 C   1 ? 
ATOM   916  O O   . LYS A 1 115 ? -15.548 5.270   -12.084 0.330 18.910  0 117 LYS 1 O   1 ? 
ATOM   917  C CB  . LYS A 1 115 ? -18.273 6.252   -12.049 0.330 20.280  0 117 LYS 1 CB  1 ? 
ATOM   918  C CG  . LYS A 1 115 ? -18.419 5.869   -10.588 0.330 20.430  0 117 LYS 1 CG  1 ? 
ATOM   919  C CD  . LYS A 1 115 ? -19.638 5.021   -10.340 0.330 20.370  0 117 LYS 1 CD  1 ? 
ATOM   920  C CE  . LYS A 1 115 ? -19.462 4.025   -9.215  0.330 20.720  0 117 LYS 1 CE  1 ? 
ATOM   921  N NZ  . LYS A 1 115 ? -20.696 3.221   -9.015  0.330 20.970  0 117 LYS 1 NZ  1 ? 
ATOM   922  N N   . VAL A 1 116 ? -14.798 7.331   -11.466 0.330 19.200  0 118 VAL 1 N   1 ? 
ATOM   923  C CA  . VAL A 1 116 ? -13.386 6.939   -11.205 0.330 20.700  0 118 VAL 1 CA  1 ? 
ATOM   924  C C   . VAL A 1 116 ? -13.170 6.785   -9.697  0.330 21.680  0 118 VAL 1 C   1 ? 
ATOM   925  O O   . VAL A 1 116 ? -13.630 7.657   -8.928  0.330 19.630  0 118 VAL 1 O   1 ? 
ATOM   926  C CB  . VAL A 1 116 ? -12.407 7.965   -11.804 0.330 21.640  0 118 VAL 1 CB  1 ? 
ATOM   927  C CG1 . VAL A 1 116 ? -10.983 7.446   -11.793 0.330 23.200  0 118 VAL 1 CG1 1 ? 
ATOM   928  C CG2 . VAL A 1 116 ? -12.813 8.369   -13.209 0.330 22.700  0 118 VAL 1 CG2 1 ? 
ATOM   929  N N   . ARG A 1 117 ? -12.454 5.734   -9.306  0.330 22.080  0 119 ARG 1 N   1 ? 
ATOM   930  C CA  . ARG A 1 117 ? -12.019 5.498   -7.908  0.330 24.190  0 119 ARG 1 CA  1 ? 
ATOM   931  C C   . ARG A 1 117 ? -10.513 5.266   -7.922  0.330 23.730  0 119 ARG 1 C   1 ? 
ATOM   932  O O   . ARG A 1 117 ? -10.036 4.501   -8.786  0.330 22.690  0 119 ARG 1 O   1 ? 
ATOM   933  C CB  . ARG A 1 117 ? -12.772 4.310   -7.305  0.330 26.060  0 119 ARG 1 CB  1 ? 
ATOM   934  C CG  . ARG A 1 117 ? -14.285 4.469   -7.324  0.330 28.620  0 119 ARG 1 CG  1 ? 
ATOM   935  C CD  . ARG A 1 117 ? -14.736 5.524   -6.334  0.330 30.620  0 119 ARG 1 CD  1 ? 
ATOM   936  N NE  . ARG A 1 117 ? -16.183 5.682   -6.296  0.330 32.010  0 119 ARG 1 NE  1 ? 
ATOM   937  C CZ  . ARG A 1 117 ? -16.861 6.650   -6.903  0.330 32.380  0 119 ARG 1 CZ  1 ? 
ATOM   938  N NH1 . ARG A 1 117 ? -16.232 7.569   -7.618  0.330 32.780  0 119 ARG 1 NH1 1 ? 
ATOM   939  N NH2 . ARG A 1 117 ? -18.175 6.691   -6.798  0.330 34.810  0 119 ARG 1 NH2 1 ? 
ATOM   940  N N   . PHE A 1 118 ? -9.788  5.917   -7.014  0.330 23.660  0 120 PHE 1 N   1 ? 
ATOM   941  C CA  . PHE A 1 118 ? -8.308  5.863   -6.933  0.330 23.490  0 120 PHE 1 CA  1 ? 
ATOM   942  C C   . PHE A 1 118 ? -7.890  5.681   -5.473  0.330 24.180  0 120 PHE 1 C   1 ? 
ATOM   943  O O   . PHE A 1 118 ? -8.170  6.593   -4.666  0.330 22.940  0 120 PHE 1 O   1 ? 
ATOM   944  C CB  . PHE A 1 118 ? -7.686  7.128   -7.538  0.330 23.150  0 120 PHE 1 CB  1 ? 
ATOM   945  C CG  . PHE A 1 118 ? -6.197  7.046   -7.762  0.330 23.440  0 120 PHE 1 CG  1 ? 
ATOM   946  C CD1 . PHE A 1 118 ? -5.310  7.171   -6.701  0.330 23.240  0 120 PHE 1 CD1 1 ? 
ATOM   947  C CD2 . PHE A 1 118 ? -5.681  6.834   -9.031  0.330 23.040  0 120 PHE 1 CD2 1 ? 
ATOM   948  C CE1 . PHE A 1 118 ? -3.942  7.066   -6.906  0.330 23.420  0 120 PHE 1 CE1 1 ? 
ATOM   949  C CE2 . PHE A 1 118 ? -4.314  6.730   -9.234  0.330 23.040  0 120 PHE 1 CE2 1 ? 
ATOM   950  C CZ  . PHE A 1 118 ? -3.448  6.844   -8.173  0.330 23.970  0 120 PHE 1 CZ  1 ? 
ATOM   951  N N   . TYR A 1 119 ? -7.208  4.568   -5.169  0.330 25.730  0 121 TYR 1 N   1 ? 
ATOM   952  C CA  . TYR A 1 119 ? -6.747  4.193   -3.803  0.330 25.980  0 121 TYR 1 CA  1 ? 
ATOM   953  C C   . TYR A 1 119 ? -5.251  3.899   -3.833  0.330 25.830  0 121 TYR 1 C   1 ? 
ATOM   954  O O   . TYR A 1 119 ? -4.815  2.964   -4.545  0.330 25.900  0 121 TYR 1 O   1 ? 
ATOM   955  C CB  . TYR A 1 119 ? -7.552  3.006   -3.262  0.330 26.050  0 121 TYR 1 CB  1 ? 
ATOM   956  C CG  . TYR A 1 119 ? -9.039  3.245   -3.296  0.330 27.850  0 121 TYR 1 CG  1 ? 
ATOM   957  C CD1 . TYR A 1 119 ? -9.620  4.214   -2.494  0.330 28.900  0 121 TYR 1 CD1 1 ? 
ATOM   958  C CD2 . TYR A 1 119 ? -9.858  2.545   -4.165  0.330 28.240  0 121 TYR 1 CD2 1 ? 
ATOM   959  C CE1 . TYR A 1 119 ? -10.979 4.472   -2.541  0.330 28.750  0 121 TYR 1 CE1 1 ? 
ATOM   960  C CE2 . TYR A 1 119 ? -11.219 2.786   -4.216  0.330 28.790  0 121 TYR 1 CE2 1 ? 
ATOM   961  C CZ  . TYR A 1 119 ? -11.781 3.755   -3.406  0.330 29.130  0 121 TYR 1 CZ  1 ? 
ATOM   962  O OH  . TYR A 1 119 ? -13.123 3.997   -3.454  0.330 31.630  0 121 TYR 1 OH  1 ? 
ATOM   963  N N   . GLY A 1 120 ? -4.489  4.700   -3.088  0.330 24.510  0 122 GLY 1 N   1 ? 
ATOM   964  C CA  . GLY A 1 120 ? -3.031  4.559   -2.947  0.330 25.850  0 122 GLY 1 CA  1 ? 
ATOM   965  C C   . GLY A 1 120 ? -2.631  4.342   -1.500  0.330 25.410  0 122 GLY 1 C   1 ? 
ATOM   966  O O   . GLY A 1 120 ? -3.318  4.876   -0.614  0.330 25.330  0 122 GLY 1 O   1 ? 
ATOM   967  N N   . THR A 1 121 ? -1.560  3.580   -1.278  0.330 26.160  0 123 THR 1 N   1 ? 
ATOM   968  C CA  . THR A 1 121 ? -1.036  3.231   0.067   0.330 26.470  0 123 THR 1 CA  1 ? 
ATOM   969  C C   . THR A 1 121 ? 0.436   2.835   -0.032  0.330 26.530  0 123 THR 1 C   1 ? 
ATOM   970  O O   . THR A 1 121 ? 0.887   2.478   -1.141  0.330 25.340  0 123 THR 1 O   1 ? 
ATOM   971  C CB  . THR A 1 121 ? -1.849  2.096   0.703   0.330 28.860  0 123 THR 1 CB  1 ? 
ATOM   972  O OG1 . THR A 1 121 ? -1.552  2.140   2.101   0.330 31.420  0 123 THR 1 OG1 1 ? 
ATOM   973  C CG2 . THR A 1 121 ? -1.535  0.744   0.100   0.330 27.840  0 123 THR 1 CG2 1 ? 
ATOM   974  N N   . ASN A 1 122 ? 1.160   2.950   1.087   0.330 26.920  0 124 ASN 1 N   1 ? 
ATOM   975  C CA  . ASN A 1 122 ? 2.521   2.388   1.268   0.330 28.530  0 124 ASN 1 CA  1 ? 
ATOM   976  C C   . ASN A 1 122 ? 3.546   3.346   0.662   0.330 26.850  0 124 ASN 1 C   1 ? 
ATOM   977  O O   . ASN A 1 122 ? 4.693   2.921   0.447   0.330 28.100  0 124 ASN 1 O   1 ? 
ATOM   978  C CB  . ASN A 1 122 ? 2.617   0.996   0.630   0.330 31.680  0 124 ASN 1 CB  1 ? 
ATOM   979  C CG  . ASN A 1 122 ? 3.335   -0.012  1.498   0.330 36.790  0 124 ASN 1 CG  1 ? 
ATOM   980  O OD1 . ASN A 1 122 ? 3.097   -0.078  2.706   0.330 40.810  0 124 ASN 1 OD1 1 ? 
ATOM   981  N ND2 . ASN A 1 122 ? 4.204   -0.806  0.891   0.330 39.510  0 124 ASN 1 ND2 1 ? 
ATOM   982  N N   . PHE A 1 123 ? 3.148   4.584   0.368   0.330 25.790  0 125 PHE 1 N   1 ? 
ATOM   983  C CA  . PHE A 1 123 ? 4.078   5.646   -0.103  0.330 25.460  0 125 PHE 1 CA  1 ? 
ATOM   984  C C   . PHE A 1 123 ? 4.891   6.122   1.094   0.330 24.710  0 125 PHE 1 C   1 ? 
ATOM   985  O O   . PHE A 1 123 ? 4.323   6.472   2.126   0.330 24.700  0 125 PHE 1 O   1 ? 
ATOM   986  C CB  . PHE A 1 123 ? 3.315   6.790   -0.770  0.330 24.990  0 125 PHE 1 CB  1 ? 
ATOM   987  C CG  . PHE A 1 123 ? 2.826   6.466   -2.157  0.330 25.040  0 125 PHE 1 CG  1 ? 
ATOM   988  C CD1 . PHE A 1 123 ? 3.713   6.397   -3.218  0.330 25.460  0 125 PHE 1 CD1 1 ? 
ATOM   989  C CD2 . PHE A 1 123 ? 1.483   6.245   -2.401  0.330 25.610  0 125 PHE 1 CD2 1 ? 
ATOM   990  C CE1 . PHE A 1 123 ? 3.270   6.077   -4.491  0.330 25.270  0 125 PHE 1 CE1 1 ? 
ATOM   991  C CE2 . PHE A 1 123 ? 1.042   5.927   -3.678  0.330 27.010  0 125 PHE 1 CE2 1 ? 
ATOM   992  C CZ  . PHE A 1 123 ? 1.936   5.858   -4.722  0.330 25.250  0 125 PHE 1 CZ  1 ? 
ATOM   993  N N   . PRO A 1 124 ? 6.240   6.099   1.001   0.330 25.630  0 126 PRO 1 N   1 ? 
ATOM   994  C CA  . PRO A 1 124 ? 7.098   6.535   2.099   0.330 25.300  0 126 PRO 1 CA  1 ? 
ATOM   995  C C   . PRO A 1 124 ? 6.982   8.054   2.298   0.330 24.750  0 126 PRO 1 C   1 ? 
ATOM   996  O O   . PRO A 1 124 ? 7.028   8.777   1.318   0.330 23.360  0 126 PRO 1 O   1 ? 
ATOM   997  C CB  . PRO A 1 124 ? 8.516   6.144   1.658   0.330 25.410  0 126 PRO 1 CB  1 ? 
ATOM   998  C CG  . PRO A 1 124 ? 8.316   5.200   0.482   0.330 25.670  0 126 PRO 1 CG  1 ? 
ATOM   999  C CD  . PRO A 1 124 ? 7.015   5.634   -0.159  0.330 25.390  0 126 PRO 1 CD  1 ? 
ATOM   1000 N N   . ALA A 1 125 ? 6.853   8.496   3.550   0.330 24.640  0 127 ALA 1 N   1 ? 
ATOM   1001 C CA  . ALA A 1 125 ? 6.660   9.916   3.920   0.330 25.360  0 127 ALA 1 CA  1 ? 
ATOM   1002 C C   . ALA A 1 125 ? 7.730   10.790  3.250   0.330 25.690  0 127 ALA 1 C   1 ? 
ATOM   1003 O O   . ALA A 1 125 ? 7.386   11.908  2.814   0.330 26.790  0 127 ALA 1 O   1 ? 
ATOM   1004 C CB  . ALA A 1 125 ? 6.686   10.057  5.417   0.330 27.510  0 127 ALA 1 CB  1 ? 
ATOM   1005 N N   . ASN A 1 126 ? 8.967   10.293  3.135   0.330 25.540  0 128 ASN 1 N   1 ? 
ATOM   1006 C CA  . ASN A 1 126 ? 10.136  11.060  2.625   0.330 27.070  0 128 ASN 1 CA  1 ? 
ATOM   1007 C C   . ASN A 1 126 ? 10.300  10.836  1.114   0.330 26.160  0 128 ASN 1 C   1 ? 
ATOM   1008 O O   . ASN A 1 126 ? 11.274  11.350  0.549   0.330 24.820  0 128 ASN 1 O   1 ? 
ATOM   1009 C CB  . ASN A 1 126 ? 11.412  10.702  3.382   0.330 29.280  0 128 ASN 1 CB  1 ? 
ATOM   1010 C CG  . ASN A 1 126 ? 11.749  9.233   3.271   0.330 32.190  0 128 ASN 1 CG  1 ? 
ATOM   1011 O OD1 . ASN A 1 126 ? 11.139  8.518   2.472   0.330 32.990  0 128 ASN 1 OD1 1 ? 
ATOM   1012 N ND2 . ASN A 1 126 ? 12.710  8.777   4.068   0.330 33.420  0 128 ASN 1 ND2 1 ? 
ATOM   1013 N N   . GLY A 1 127 ? 9.350   10.142  0.481   0.330 25.560  0 129 GLY 1 N   1 ? 
ATOM   1014 C CA  . GLY A 1 127 ? 9.400   9.782   -0.949  0.330 24.930  0 129 GLY 1 CA  1 ? 
ATOM   1015 C C   . GLY A 1 127 ? 8.937   10.922  -1.855  0.330 23.900  0 129 GLY 1 C   1 ? 
ATOM   1016 O O   . GLY A 1 127 ? 8.278   11.862  -1.414  0.330 22.670  0 129 GLY 1 O   1 ? 
ATOM   1017 N N   . PRO A 1 128 ? 9.295   10.881  -3.155  0.330 23.290  0 130 PRO 1 N   1 ? 
ATOM   1018 C CA  . PRO A 1 128 ? 8.987   11.968  -4.083  0.330 22.860  0 130 PRO 1 CA  1 ? 
ATOM   1019 C C   . PRO A 1 128 ? 7.491   12.294  -4.198  0.330 22.570  0 130 PRO 1 C   1 ? 
ATOM   1020 O O   . PRO A 1 128 ? 7.174   13.442  -4.469  0.330 22.830  0 130 PRO 1 O   1 ? 
ATOM   1021 C CB  . PRO A 1 128 ? 9.543   11.466  -5.431  0.330 23.300  0 130 PRO 1 CB  1 ? 
ATOM   1022 C CG  . PRO A 1 128 ? 9.719   9.973   -5.258  0.330 23.800  0 130 PRO 1 CG  1 ? 
ATOM   1023 C CD  . PRO A 1 128 ? 10.047  9.793   -3.796  0.330 24.120  0 130 PRO 1 CD  1 ? 
ATOM   1024 N N   . VAL A 1 129 ? 6.619   11.309  -3.966  0.330 21.380  0 131 VAL 1 N   1 ? 
ATOM   1025 C CA  . VAL A 1 129 ? 5.141   11.447  -4.103  0.330 22.050  0 131 VAL 1 CA  1 ? 
ATOM   1026 C C   . VAL A 1 129 ? 4.591   12.290  -2.941  0.330 20.940  0 131 VAL 1 C   1 ? 
ATOM   1027 O O   . VAL A 1 129 ? 3.894   13.277  -3.192  0.330 21.300  0 131 VAL 1 O   1 ? 
ATOM   1028 C CB  . VAL A 1 129 ? 4.456   10.073  -4.202  0.330 22.610  0 131 VAL 1 CB  1 ? 
ATOM   1029 C CG1 . VAL A 1 129 ? 2.957   10.185  -3.986  0.330 23.270  0 131 VAL 1 CG1 1 ? 
ATOM   1030 C CG2 . VAL A 1 129 ? 4.761   9.392   -5.527  0.330 23.720  0 131 VAL 1 CG2 1 ? 
ATOM   1031 N N   . MET A 1 130 ? 4.942   11.960  -1.705  0.330 21.270  0 132 MET 1 N   1 ? 
ATOM   1032 C CA  . MET A 1 130 ? 4.434   12.689  -0.512  0.330 22.120  0 132 MET 1 CA  1 ? 
ATOM   1033 C C   . MET A 1 130 ? 5.211   14.005  -0.306  0.330 21.950  0 132 MET 1 C   1 ? 
ATOM   1034 O O   . MET A 1 130 ? 4.717   14.849  0.456   0.330 24.390  0 132 MET 1 O   1 ? 
ATOM   1035 C CB  . MET A 1 130 ? 4.531   11.810  0.739   0.330 22.380  0 132 MET 1 CB  1 ? 
ATOM   1036 C CG  . MET A 1 130 ? 3.715   10.540  0.657   0.330 23.090  0 132 MET 1 CG  1 ? 
ATOM   1037 S SD  . MET A 1 130 ? 1.982   10.834  0.215   0.330 25.000  0 132 MET 1 SD  1 ? 
ATOM   1038 C CE  . MET A 1 130 ? 1.436   11.782  1.632   0.330 23.490  0 132 MET 1 CE  1 ? 
ATOM   1039 N N   . GLN A 1 131 ? 6.357   14.193  -0.972  0.330 21.300  0 133 GLN 1 N   1 ? 
ATOM   1040 C CA  . GLN A 1 131 ? 7.192   15.424  -0.854  0.330 21.170  0 133 GLN 1 CA  1 ? 
ATOM   1041 C C   . GLN A 1 131 ? 6.950   16.344  -2.062  0.330 21.830  0 133 GLN 1 C   1 ? 
ATOM   1042 O O   . GLN A 1 131 ? 7.454   17.490  -2.052  0.330 21.730  0 133 GLN 1 O   1 ? 
ATOM   1043 C CB  . GLN A 1 131 ? 8.672   15.071  -0.738  0.330 21.640  0 133 GLN 1 CB  1 ? 
ATOM   1044 C CG  . GLN A 1 131 ? 9.046   14.401  0.583   0.330 22.050  0 133 GLN 1 CG  1 ? 
ATOM   1045 C CD  . GLN A 1 131 ? 8.814   15.299  1.773   0.330 22.000  0 133 GLN 1 CD  1 ? 
ATOM   1046 O OE1 . GLN A 1 131 ? 8.977   16.512  1.695   0.330 21.650  0 133 GLN 1 OE1 1 ? 
ATOM   1047 N NE2 . GLN A 1 131 ? 8.432   14.704  2.892   0.330 22.360  0 133 GLN 1 NE2 1 ? 
ATOM   1048 N N   . LYS A 1 132 ? 6.210   15.849  -3.061  0.330 22.860  0 134 LYS 1 N   1 ? 
ATOM   1049 C CA  . LYS A 1 132 ? 5.790   16.609  -4.267  0.330 23.940  0 134 LYS 1 CA  1 ? 
ATOM   1050 C C   . LYS A 1 132 ? 7.016   17.001  -5.098  0.330 23.400  0 134 LYS 1 C   1 ? 
ATOM   1051 O O   . LYS A 1 132 ? 7.155   18.201  -5.389  0.330 23.520  0 134 LYS 1 O   1 ? 
ATOM   1052 C CB  . LYS A 1 132 ? 5.018   17.870  -3.872  0.330 24.240  0 134 LYS 1 CB  1 ? 
ATOM   1053 C CG  . LYS A 1 132 ? 3.714   17.615  -3.131  0.330 25.990  0 134 LYS 1 CG  1 ? 
ATOM   1054 C CD  . LYS A 1 132 ? 3.005   18.896  -2.742  0.330 27.020  0 134 LYS 1 CD  1 ? 
ATOM   1055 C CE  . LYS A 1 132 ? 1.964   18.701  -1.663  0.330 28.420  0 134 LYS 1 CE  1 ? 
ATOM   1056 N NZ  . LYS A 1 132 ? 1.167   19.935  -1.453  0.330 29.050  0 134 LYS 1 NZ  1 ? 
ATOM   1057 N N   . LYS A 1 133 ? 7.837   16.022  -5.485  0.330 22.690  0 135 LYS 1 N   1 ? 
ATOM   1058 C CA  . LYS A 1 133 ? 9.092   16.227  -6.256  0.330 23.370  0 135 LYS 1 CA  1 ? 
ATOM   1059 C C   . LYS A 1 133 ? 8.945   15.765  -7.713  0.330 23.730  0 135 LYS 1 C   1 ? 
ATOM   1060 O O   . LYS A 1 133 ? 9.974   15.730  -8.421  0.330 25.570  0 135 LYS 1 O   1 ? 
ATOM   1061 C CB  . LYS A 1 133 ? 10.233  15.452  -5.592  0.330 24.430  0 135 LYS 1 CB  1 ? 
ATOM   1062 C CG  . LYS A 1 133 ? 10.434  15.776  -4.124  0.330 25.830  0 135 LYS 1 CG  1 ? 
ATOM   1063 C CD  . LYS A 1 133 ? 10.635  17.255  -3.872  0.330 26.180  0 135 LYS 1 CD  1 ? 
ATOM   1064 C CE  . LYS A 1 133 ? 12.019  17.733  -4.245  0.330 26.470  0 135 LYS 1 CE  1 ? 
ATOM   1065 N NZ  . LYS A 1 133 ? 12.150  19.201  -4.076  0.330 26.270  0 135 LYS 1 NZ  1 ? 
ATOM   1066 N N   . THR A 1 134 ? 7.743   15.392  -8.153  0.330 23.450  0 136 THR 1 N   1 ? 
ATOM   1067 C CA  . THR A 1 134 ? 7.514   14.855  -9.521  0.330 23.190  0 136 THR 1 CA  1 ? 
ATOM   1068 C C   . THR A 1 134 ? 7.318   16.013  -10.505 0.330 24.980  0 136 THR 1 C   1 ? 
ATOM   1069 O O   . THR A 1 134 ? 6.696   17.030  -10.116 0.330 24.890  0 136 THR 1 O   1 ? 
ATOM   1070 C CB  . THR A 1 134 ? 6.321   13.898  -9.544  0.330 23.040  0 136 THR 1 CB  1 ? 
ATOM   1071 O OG1 . THR A 1 134 ? 5.150   14.682  -9.328  0.330 24.520  0 136 THR 1 OG1 1 ? 
ATOM   1072 C CG2 . THR A 1 134 ? 6.431   12.803  -8.510  0.330 22.550  0 136 THR 1 CG2 1 ? 
ATOM   1073 N N   . LEU A 1 135 ? 7.816   15.855  -11.737 0.330 25.110  0 137 LEU 1 N   1 ? 
ATOM   1074 C CA  . LEU A 1 135 ? 7.741   16.894  -12.799 0.330 24.550  0 137 LEU 1 CA  1 ? 
ATOM   1075 C C   . LEU A 1 135 ? 6.761   16.445  -13.888 0.330 24.310  0 137 LEU 1 C   1 ? 
ATOM   1076 O O   . LEU A 1 135 ? 5.988   17.293  -14.378 0.330 22.720  0 137 LEU 1 O   1 ? 
ATOM   1077 C CB  . LEU A 1 135 ? 9.141   17.129  -13.375 0.330 25.430  0 137 LEU 1 CB  1 ? 
ATOM   1078 C CG  . LEU A 1 135 ? 10.135  17.796  -12.426 0.330 27.780  0 137 LEU 1 CG  1 ? 
ATOM   1079 C CD1 . LEU A 1 135 ? 11.422  18.157  -13.158 0.330 28.730  0 137 LEU 1 CD1 1 ? 
ATOM   1080 C CD2 . LEU A 1 135 ? 9.525   19.033  -11.791 0.330 28.550  0 137 LEU 1 CD2 1 ? 
ATOM   1081 N N   . LYS A 1 136 ? 6.782   15.163  -14.267 0.330 23.900  0 138 LYS 1 N   1 ? 
ATOM   1082 C CA  . LYS A 1 136 ? 5.896   14.661  -15.345 0.330 24.560  0 138 LYS 1 CA  1 ? 
ATOM   1083 C C   . LYS A 1 136 ? 6.079   13.163  -15.572 0.330 23.820  0 138 LYS 1 C   1 ? 
ATOM   1084 O O   . LYS A 1 136 ? 7.079   12.614  -15.101 0.330 25.850  0 138 LYS 1 O   1 ? 
ATOM   1085 C CB  . LYS A 1 136 ? 6.202   15.385  -16.656 0.330 25.920  0 138 LYS 1 CB  1 ? 
ATOM   1086 C CG  . LYS A 1 136 ? 7.582   15.123  -17.230 0.330 27.210  0 138 LYS 1 CG  1 ? 
ATOM   1087 C CD  . LYS A 1 136 ? 7.684   15.485  -18.695 0.330 29.560  0 138 LYS 1 CD  1 ? 
ATOM   1088 C CE  . LYS A 1 136 ? 9.034   15.141  -19.281 0.330 31.990  0 138 LYS 1 CE  1 ? 
ATOM   1089 N NZ  . LYS A 1 136 ? 8.918   14.660  -20.679 0.330 33.070  0 138 LYS 1 NZ  1 ? 
ATOM   1090 N N   . TRP A 1 137 ? 5.136   12.554  -16.292 0.330 23.220  0 139 TRP 1 N   1 ? 
ATOM   1091 C CA  . TRP A 1 137 ? 5.252   11.192  -16.872 0.330 23.130  0 139 TRP 1 CA  1 ? 
ATOM   1092 C C   . TRP A 1 137 ? 6.063   11.285  -18.166 0.330 23.560  0 139 TRP 1 C   1 ? 
ATOM   1093 O O   . TRP A 1 137 ? 5.827   12.215  -18.944 0.330 24.990  0 139 TRP 1 O   1 ? 
ATOM   1094 C CB  . TRP A 1 137 ? 3.868   10.578  -17.137 0.330 23.450  0 139 TRP 1 CB  1 ? 
ATOM   1095 C CG  . TRP A 1 137 ? 3.070   10.277  -15.903 0.330 23.890  0 139 TRP 1 CG  1 ? 
ATOM   1096 C CD1 . TRP A 1 137 ? 2.117   11.068  -15.328 0.330 23.020  0 139 TRP 1 CD1 1 ? 
ATOM   1097 C CD2 . TRP A 1 137 ? 3.144   9.091   -15.092 0.330 23.160  0 139 TRP 1 CD2 1 ? 
ATOM   1098 N NE1 . TRP A 1 137 ? 1.602   10.460  -14.217 0.330 23.730  0 139 TRP 1 NE1 1 ? 
ATOM   1099 C CE2 . TRP A 1 137 ? 2.211   9.249   -14.044 0.330 22.960  0 139 TRP 1 CE2 1 ? 
ATOM   1100 C CE3 . TRP A 1 137 ? 3.904   7.921   -15.144 0.330 23.370  0 139 TRP 1 CE3 1 ? 
ATOM   1101 C CZ2 . TRP A 1 137 ? 2.012   8.277   -13.068 0.330 23.330  0 139 TRP 1 CZ2 1 ? 
ATOM   1102 C CZ3 . TRP A 1 137 ? 3.716   6.966   -14.171 0.330 23.630  0 139 TRP 1 CZ3 1 ? 
ATOM   1103 C CH2 . TRP A 1 137 ? 2.784   7.141   -13.150 0.330 22.870  0 139 TRP 1 CH2 1 ? 
ATOM   1104 N N   . GLU A 1 138 ? 6.983   10.354  -18.387 0.330 23.170  0 140 GLU 1 N   1 ? 
ATOM   1105 C CA  . GLU A 1 138 ? 7.668   10.206  -19.690 0.330 23.540  0 140 GLU 1 CA  1 ? 
ATOM   1106 C C   . GLU A 1 138 ? 6.689   9.562   -20.667 0.330 23.790  0 140 GLU 1 C   1 ? 
ATOM   1107 O O   . GLU A 1 138 ? 5.844   8.757   -20.273 0.330 23.980  0 140 GLU 1 O   1 ? 
ATOM   1108 C CB  . GLU A 1 138 ? 8.948   9.385   -19.534 0.330 23.460  0 140 GLU 1 CB  1 ? 
ATOM   1109 C CG  . GLU A 1 138 ? 10.001  10.079  -18.686 0.330 24.480  0 140 GLU 1 CG  1 ? 
ATOM   1110 C CD  . GLU A 1 138 ? 10.617  11.324  -19.302 0.330 24.280  0 140 GLU 1 CD  1 ? 
ATOM   1111 O OE1 . GLU A 1 138 ? 9.958   11.976  -20.140 0.330 25.230  0 140 GLU 1 OE1 1 ? 
ATOM   1112 O OE2 . GLU A 1 138 ? 11.759  11.631  -18.940 0.330 25.030  0 140 GLU 1 OE2 1 ? 
ATOM   1113 N N   . PRO A 1 139 ? 6.782   9.890   -21.971 0.330 23.270  0 141 PRO 1 N   1 ? 
ATOM   1114 C CA  . PRO A 1 139 ? 5.988   9.203   -22.985 0.330 23.600  0 141 PRO 1 CA  1 ? 
ATOM   1115 C C   . PRO A 1 139 ? 6.174   7.696   -22.767 0.330 23.010  0 141 PRO 1 C   1 ? 
ATOM   1116 O O   . PRO A 1 139 ? 7.241   7.308   -22.310 0.330 22.720  0 141 PRO 1 O   1 ? 
ATOM   1117 C CB  . PRO A 1 139 ? 6.566   9.712   -24.316 0.330 24.140  0 141 PRO 1 CB  1 ? 
ATOM   1118 C CG  . PRO A 1 139 ? 7.180   11.048  -23.967 0.330 24.950  0 141 PRO 1 CG  1 ? 
ATOM   1119 C CD  . PRO A 1 139 ? 7.651   10.933  -22.533 0.330 24.430  0 141 PRO 1 CD  1 ? 
ATOM   1120 N N   . SER A 1 140 ? 5.144   6.900   -23.056 0.330 22.830  0 142 SER 1 N   1 ? 
ATOM   1121 C CA  . SER A 1 140 ? 5.107   5.448   -22.767 0.330 23.740  0 142 SER 1 CA  1 ? 
ATOM   1122 C C   . SER A 1 140 ? 4.534   4.688   -23.963 0.330 24.290  0 142 SER 1 C   1 ? 
ATOM   1123 O O   . SER A 1 140 ? 3.945   5.327   -24.852 0.330 23.410  0 142 SER 1 O   1 ? 
ATOM   1124 C CB  . SER A 1 140 ? 4.310   5.159   -21.519 0.330 24.680  0 142 SER 1 CB  1 ? 
ATOM   1125 O OG  . SER A 1 140 ? 2.923   5.389   -21.731 0.330 24.530  0 142 SER 1 OG  1 ? 
ATOM   1126 N N   . THR A 1 141 ? 4.725   3.369   -23.963 0.330 23.150  0 143 THR 1 N   1 ? 
ATOM   1127 C CA  . THR A 1 141 ? 4.114   2.420   -24.925 0.330 23.980  0 143 THR 1 CA  1 ? 
ATOM   1128 C C   . THR A 1 141 ? 3.383   1.339   -24.130 0.330 23.110  0 143 THR 1 C   1 ? 
ATOM   1129 O O   . THR A 1 141 ? 4.049   0.640   -23.343 0.330 24.670  0 143 THR 1 O   1 ? 
ATOM   1130 C CB  . THR A 1 141 ? 5.154   1.791   -25.859 0.330 23.900  0 143 THR 1 CB  1 ? 
ATOM   1131 O OG1 . THR A 1 141 ? 5.726   2.829   -26.660 0.330 23.440  0 143 THR 1 OG1 1 ? 
ATOM   1132 C CG2 . THR A 1 141 ? 4.543   0.736   -26.754 0.330 23.630  0 143 THR 1 CG2 1 ? 
ATOM   1133 N N   . GLU A 1 142 ? 2.066   1.248   -24.304 0.330 23.150  0 144 GLU 1 N   1 ? 
ATOM   1134 C CA  . GLU A 1 142 ? 1.200   0.252   -23.625 0.330 22.100  0 144 GLU 1 CA  1 ? 
ATOM   1135 C C   . GLU A 1 142 ? 1.096   -0.986  -24.520 0.330 22.920  0 144 GLU 1 C   1 ? 
ATOM   1136 O O   . GLU A 1 142 ? 0.577   -0.854  -25.645 0.330 23.010  0 144 GLU 1 O   1 ? 
ATOM   1137 C CB  . GLU A 1 142 ? -0.175  0.854   -23.332 0.330 22.560  0 144 GLU 1 CB  1 ? 
ATOM   1138 C CG  . GLU A 1 142 ? -1.147  -0.129  -22.703 0.330 21.870  0 144 GLU 1 CG  1 ? 
ATOM   1139 C CD  . GLU A 1 142 ? -2.439  0.473   -22.180 0.330 23.740  0 144 GLU 1 CD  1 ? 
ATOM   1140 O OE1 . GLU A 1 142 ? -2.828  1.560   -22.664 0.330 25.530  0 144 GLU 1 OE1 1 ? 
ATOM   1141 O OE2 . GLU A 1 142 ? -3.043  -0.144  -21.274 0.330 24.850  0 144 GLU 1 OE2 1 ? 
ATOM   1142 N N   . LYS A 1 143 ? 1.596   -2.130  -24.052 0.330 22.530  0 145 LYS 1 N   1 ? 
ATOM   1143 C CA  . LYS A 1 143 ? 1.497   -3.425  -24.778 0.330 23.260  0 145 LYS 1 CA  1 ? 
ATOM   1144 C C   . LYS A 1 143 ? 0.119   -4.023  -24.506 0.330 22.720  0 145 LYS 1 C   1 ? 
ATOM   1145 O O   . LYS A 1 143 ? -0.178  -4.311  -23.330 0.330 23.840  0 145 LYS 1 O   1 ? 
ATOM   1146 C CB  . LYS A 1 143 ? 2.581   -4.418  -24.349 0.330 24.400  0 145 LYS 1 CB  1 ? 
ATOM   1147 C CG  . LYS A 1 143 ? 4.010   -4.030  -24.704 0.330 26.670  0 145 LYS 1 CG  1 ? 
ATOM   1148 C CD  . LYS A 1 143 ? 5.055   -4.983  -24.105 0.330 27.900  0 145 LYS 1 CD  1 ? 
ATOM   1149 C CE  . LYS A 1 143 ? 4.824   -5.276  -22.632 0.330 27.280  0 145 LYS 1 CE  1 ? 
ATOM   1150 N NZ  . LYS A 1 143 ? 6.039   -5.805  -21.960 0.330 26.430  0 145 LYS 1 NZ  1 ? 
ATOM   1151 N N   . MET A 1 144 ? -0.679  -4.207  -25.556 0.330 23.880  0 146 MET 1 N   1 ? 
ATOM   1152 C CA  . MET A 1 144 ? -2.055  -4.771  -25.495 0.330 24.160  0 146 MET 1 CA  1 ? 
ATOM   1153 C C   . MET A 1 144 ? -2.037  -6.240  -25.926 0.330 23.410  0 146 MET 1 C   1 ? 
ATOM   1154 O O   . MET A 1 144 ? -1.584  -6.528  -27.047 0.330 23.120  0 146 MET 1 O   1 ? 
ATOM   1155 C CB  . MET A 1 144 ? -2.993  -4.003  -26.426 0.330 26.170  0 146 MET 1 CB  1 ? 
ATOM   1156 C CG  . MET A 1 144 ? -3.168  -2.548  -26.035 0.330 28.200  0 146 MET 1 CG  1 ? 
ATOM   1157 S SD  . MET A 1 144 ? -4.102  -2.379  -24.494 0.330 29.240  0 146 MET 1 SD  1 ? 
ATOM   1158 C CE  . MET A 1 144 ? -4.953  -0.828  -24.780 0.330 30.550  0 146 MET 1 CE  1 ? 
ATOM   1159 N N   . TYR A 1 145 ? -2.567  -7.126  -25.090 0.330 22.810  0 147 TYR 1 N   1 ? 
ATOM   1160 C CA  . TYR A 1 145 ? -2.646  -8.580  -25.369 0.330 24.050  0 147 TYR 1 CA  1 ? 
ATOM   1161 C C   . TYR A 1 145 ? -3.779  -9.187  -24.539 0.330 24.990  0 147 TYR 1 C   1 ? 
ATOM   1162 O O   . TYR A 1 145 ? -4.281  -8.543  -23.611 0.330 24.860  0 147 TYR 1 O   1 ? 
ATOM   1163 C CB  . TYR A 1 145 ? -1.297  -9.252  -25.076 0.330 24.290  0 147 TYR 1 CB  1 ? 
ATOM   1164 C CG  . TYR A 1 145 ? -0.876  -9.162  -23.631 0.330 23.160  0 147 TYR 1 CG  1 ? 
ATOM   1165 C CD1 . TYR A 1 145 ? -0.194  -8.056  -23.158 0.330 23.580  0 147 TYR 1 CD1 1 ? 
ATOM   1166 C CD2 . TYR A 1 145 ? -1.190  -10.166 -22.730 0.330 23.580  0 147 TYR 1 CD2 1 ? 
ATOM   1167 C CE1 . TYR A 1 145 ? 0.165   -7.943  -21.826 0.330 23.390  0 147 TYR 1 CE1 1 ? 
ATOM   1168 C CE2 . TYR A 1 145 ? -0.839  -10.070 -21.394 0.330 23.440  0 147 TYR 1 CE2 1 ? 
ATOM   1169 C CZ  . TYR A 1 145 ? -0.158  -8.955  -20.940 0.330 23.510  0 147 TYR 1 CZ  1 ? 
ATOM   1170 O OH  . TYR A 1 145 ? 0.224   -8.853  -19.636 0.330 22.990  0 147 TYR 1 OH  1 ? 
ATOM   1171 N N   . VAL A 1 146 ? -4.125  -10.436 -24.842 0.330 25.970  0 148 VAL 1 N   1 ? 
ATOM   1172 C CA  . VAL A 1 146 ? -5.211  -11.178 -24.154 0.330 28.360  0 148 VAL 1 CA  1 ? 
ATOM   1173 C C   . VAL A 1 146 ? -4.574  -12.177 -23.192 0.330 29.810  0 148 VAL 1 C   1 ? 
ATOM   1174 O O   . VAL A 1 146 ? -3.713  -12.956 -23.631 0.330 30.230  0 148 VAL 1 O   1 ? 
ATOM   1175 C CB  . VAL A 1 146 ? -6.131  -11.866 -25.173 0.330 28.820  0 148 VAL 1 CB  1 ? 
ATOM   1176 C CG1 . VAL A 1 146 ? -7.225  -12.657 -24.489 0.330 29.770  0 148 VAL 1 CG1 1 ? 
ATOM   1177 C CG2 . VAL A 1 146 ? -6.713  -10.862 -26.155 0.330 29.150  0 148 VAL 1 CG2 1 ? 
ATOM   1178 N N   . ARG A 1 147 ? -4.997  -12.135 -21.931 0.330 31.290  0 149 ARG 1 N   1 ? 
ATOM   1179 C CA  . ARG A 1 147 ? -4.551  -13.044 -20.849 0.330 32.190  0 149 ARG 1 CA  1 ? 
ATOM   1180 C C   . ARG A 1 147 ? -5.802  -13.650 -20.204 0.330 33.900  0 149 ARG 1 C   1 ? 
ATOM   1181 O O   . ARG A 1 147 ? -6.611  -12.883 -19.647 0.330 32.150  0 149 ARG 1 O   1 ? 
ATOM   1182 C CB  . ARG A 1 147 ? -3.700  -12.256 -19.854 0.330 35.090  0 149 ARG 1 CB  1 ? 
ATOM   1183 C CG  . ARG A 1 147 ? -3.104  -13.087 -18.724 0.330 37.970  0 149 ARG 1 CG  1 ? 
ATOM   1184 C CD  . ARG A 1 147 ? -2.685  -12.148 -17.612 0.330 39.130  0 149 ARG 1 CD  1 ? 
ATOM   1185 N NE  . ARG A 1 147 ? -1.501  -12.554 -16.864 0.330 43.530  0 149 ARG 1 NE  1 ? 
ATOM   1186 C CZ  . ARG A 1 147 ? -0.282  -12.066 -17.087 0.330 43.010  0 149 ARG 1 CZ  1 ? 
ATOM   1187 N NH1 . ARG A 1 147 ? -0.096  -11.188 -18.060 0.330 41.040  0 149 ARG 1 NH1 1 ? 
ATOM   1188 N NH2 . ARG A 1 147 ? 0.743   -12.459 -16.350 0.330 42.050  0 149 ARG 1 NH2 1 ? 
ATOM   1189 N N   . ASP A 1 148 ? -5.958  -14.970 -20.325 0.330 34.630  0 150 ASP 1 N   1 ? 
ATOM   1190 C CA  . ASP A 1 148 ? -7.155  -15.744 -19.898 0.330 34.450  0 150 ASP 1 CA  1 ? 
ATOM   1191 C C   . ASP A 1 148 ? -8.429  -14.982 -20.275 0.330 32.070  0 150 ASP 1 C   1 ? 
ATOM   1192 O O   . ASP A 1 148 ? -9.219  -14.657 -19.365 0.330 31.960  0 150 ASP 1 O   1 ? 
ATOM   1193 C CB  . ASP A 1 148 ? -7.113  -16.058 -18.402 0.330 35.140  0 150 ASP 1 CB  1 ? 
ATOM   1194 C CG  . ASP A 1 148 ? -7.805  -17.363 -18.051 0.330 35.740  0 150 ASP 1 CG  1 ? 
ATOM   1195 O OD1 . ASP A 1 148 ? -8.268  -18.058 -18.984 0.330 32.950  0 150 ASP 1 OD1 1 ? 
ATOM   1196 O OD2 . ASP A 1 148 ? -7.862  -17.679 -16.850 0.330 35.230  0 150 ASP 1 OD2 1 ? 
ATOM   1197 N N   . GLY A 1 149 ? -8.611  -14.710 -21.571 0.330 28.550  0 151 GLY 1 N   1 ? 
ATOM   1198 C CA  . GLY A 1 149 ? -9.856  -14.167 -22.139 0.330 26.760  0 151 GLY 1 CA  1 ? 
ATOM   1199 C C   . GLY A 1 149 ? -10.166 -12.753 -21.665 0.330 27.260  0 151 GLY 1 C   1 ? 
ATOM   1200 O O   . GLY A 1 149 ? -11.341 -12.334 -21.778 0.330 26.680  0 151 GLY 1 O   1 ? 
ATOM   1201 N N   . VAL A 1 150 ? -9.162  -12.003 -21.201 0.330 26.000  0 152 VAL 1 N   1 ? 
ATOM   1202 C CA  . VAL A 1 150 ? -9.352  -10.579 -20.798 0.330 25.650  0 152 VAL 1 CA  1 ? 
ATOM   1203 C C   . VAL A 1 150 ? -8.317  -9.695  -21.501 0.330 23.890  0 152 VAL 1 C   1 ? 
ATOM   1204 O O   . VAL A 1 150 ? -7.129  -10.012 -21.448 0.330 24.780  0 152 VAL 1 O   1 ? 
ATOM   1205 C CB  . VAL A 1 150 ? -9.278  -10.418 -19.270 0.330 25.840  0 152 VAL 1 CB  1 ? 
ATOM   1206 C CG1 . VAL A 1 150 ? -9.407  -8.960  -18.864 0.330 26.850  0 152 VAL 1 CG1 1 ? 
ATOM   1207 C CG2 . VAL A 1 150 ? -10.325 -11.256 -18.566 0.330 27.970  0 152 VAL 1 CG2 1 ? 
ATOM   1208 N N   . LEU A 1 151 ? -8.760  -8.602  -22.120 0.330 23.270  0 153 LEU 1 N   1 ? 
ATOM   1209 C CA  . LEU A 1 151 ? -7.866  -7.615  -22.769 0.330 21.970  0 153 LEU 1 CA  1 ? 
ATOM   1210 C C   . LEU A 1 151 ? -7.051  -6.918  -21.678 0.330 21.720  0 153 LEU 1 C   1 ? 
ATOM   1211 O O   . LEU A 1 151 ? -7.671  -6.330  -20.765 0.330 22.870  0 153 LEU 1 O   1 ? 
ATOM   1212 C CB  . LEU A 1 151 ? -8.696  -6.614  -23.567 0.330 22.370  0 153 LEU 1 CB  1 ? 
ATOM   1213 C CG  . LEU A 1 151 ? -7.870  -5.561  -24.296 0.330 22.860  0 153 LEU 1 CG  1 ? 
ATOM   1214 C CD1 . LEU A 1 151 ? -6.900  -6.224  -25.259 0.330 23.230  0 153 LEU 1 CD1 1 ? 
ATOM   1215 C CD2 . LEU A 1 151 ? -8.776  -4.570  -25.009 0.330 23.690  0 153 LEU 1 CD2 1 ? 
ATOM   1216 N N   . THR A 1 152 ? -5.723  -7.015  -21.768 0.330 22.220  0 154 THR 1 N   1 ? 
ATOM   1217 C CA  . THR A 1 152 ? -4.744  -6.575  -20.739 0.330 21.920  0 154 THR 1 CA  1 ? 
ATOM   1218 C C   . THR A 1 152 ? -3.736  -5.632  -21.388 0.330 22.340  0 154 THR 1 C   1 ? 
ATOM   1219 O O   . THR A 1 152 ? -3.287  -5.923  -22.524 0.330 21.340  0 154 THR 1 O   1 ? 
ATOM   1220 C CB  . THR A 1 152 ? -4.049  -7.774  -20.075 0.330 22.160  0 154 THR 1 CB  1 ? 
ATOM   1221 O OG1 . THR A 1 152 ? -5.081  -8.658  -19.642 0.330 22.350  0 154 THR 1 OG1 1 ? 
ATOM   1222 C CG2 . THR A 1 152 ? -3.178  -7.383  -18.902 0.330 21.950  0 154 THR 1 CG2 1 ? 
ATOM   1223 N N   . GLY A 1 153 ? -3.420  -4.530  -20.702 0.330 22.180  0 155 GLY 1 N   1 ? 
ATOM   1224 C CA  . GLY A 1 153 ? -2.382  -3.561  -21.110 0.330 21.790  0 155 GLY 1 CA  1 ? 
ATOM   1225 C C   . GLY A 1 153 ? -1.302  -3.442  -20.052 0.330 21.410  0 155 GLY 1 C   1 ? 
ATOM   1226 O O   . GLY A 1 153 ? -1.640  -3.235  -18.877 0.330 22.360  0 155 GLY 1 O   1 ? 
ATOM   1227 N N   . ASP A 1 154 ? -0.042  -3.604  -20.453 0.330 22.270  0 156 ASP 1 N   1 ? 
ATOM   1228 C CA  . ASP A 1 154 ? 1.144   -3.449  -19.572 0.330 23.010  0 156 ASP 1 CA  1 ? 
ATOM   1229 C C   . ASP A 1 154 ? 1.905   -2.187  -19.994 0.330 22.870  0 156 ASP 1 C   1 ? 
ATOM   1230 O O   . ASP A 1 154 ? 2.080   -1.967  -21.206 0.330 22.730  0 156 ASP 1 O   1 ? 
ATOM   1231 C CB  . ASP A 1 154 ? 2.039   -4.687  -19.626 0.330 23.780  0 156 ASP 1 CB  1 ? 
ATOM   1232 C CG  . ASP A 1 154 ? 1.461   -5.890  -18.904 0.330 24.590  0 156 ASP 1 CG  1 ? 
ATOM   1233 O OD1 . ASP A 1 154 ? 0.504   -5.714  -18.134 0.330 24.790  0 156 ASP 1 OD1 1 ? 
ATOM   1234 O OD2 . ASP A 1 154 ? 1.969   -6.994  -19.127 0.330 25.520  0 156 ASP 1 OD2 1 ? 
ATOM   1235 N N   . VAL A 1 155 ? 2.319   -1.377  -19.024 0.330 22.350  0 157 VAL 1 N   1 ? 
ATOM   1236 C CA  . VAL A 1 155 ? 3.139   -0.152  -19.252 0.330 22.770  0 157 VAL 1 CA  1 ? 
ATOM   1237 C C   . VAL A 1 155 ? 4.308   -0.178  -18.264 0.330 23.200  0 157 VAL 1 C   1 ? 
ATOM   1238 O O   . VAL A 1 155 ? 4.029   -0.219  -17.072 0.330 23.210  0 157 VAL 1 O   1 ? 
ATOM   1239 C CB  . VAL A 1 155 ? 2.309   1.131   -19.048 0.330 21.890  0 157 VAL 1 CB  1 ? 
ATOM   1240 C CG1 . VAL A 1 155 ? 3.084   2.353   -19.486 0.330 22.280  0 157 VAL 1 CG1 1 ? 
ATOM   1241 C CG2 . VAL A 1 155 ? 0.956   1.073   -19.743 0.330 21.340  0 157 VAL 1 CG2 1 ? 
ATOM   1242 N N   . GLU A 1 156 ? 5.549   -0.168  -18.754 0.330 25.040  0 158 GLU 1 N   1 ? 
ATOM   1243 C CA  . GLU A 1 156 ? 6.777   0.072   -17.943 0.330 27.260  0 158 GLU 1 CA  1 ? 
ATOM   1244 C C   . GLU A 1 156 ? 7.223   1.515   -18.196 0.330 25.730  0 158 GLU 1 C   1 ? 
ATOM   1245 O O   . GLU A 1 156 ? 7.686   1.808   -19.303 0.330 25.830  0 158 GLU 1 O   1 ? 
ATOM   1246 C CB  . GLU A 1 156 ? 7.878   -0.941  -18.297 0.330 29.690  0 158 GLU 1 CB  1 ? 
ATOM   1247 C CG  . GLU A 1 156 ? 7.419   -2.393  -18.214 0.330 32.200  0 158 GLU 1 CG  1 ? 
ATOM   1248 C CD  . GLU A 1 156 ? 8.476   -3.449  -18.522 0.330 35.530  0 158 GLU 1 CD  1 ? 
ATOM   1249 O OE1 . GLU A 1 156 ? 9.385   -3.173  -19.356 0.330 36.910  0 158 GLU 1 OE1 1 ? 
ATOM   1250 O OE2 . GLU A 1 156 ? 8.399   -4.552  -17.910 0.330 36.610  0 158 GLU 1 OE2 1 ? 
ATOM   1251 N N   . THR A 1 157 ? 7.037   2.404   -17.222 0.330 25.490  0 159 THR 1 N   1 ? 
ATOM   1252 C CA  . THR A 1 157 ? 7.198   3.869   -17.411 0.330 25.440  0 159 THR 1 CA  1 ? 
ATOM   1253 C C   . THR A 1 157 ? 7.907   4.451   -16.183 0.330 24.230  0 159 THR 1 C   1 ? 
ATOM   1254 O O   . THR A 1 157 ? 8.392   3.677   -15.338 0.330 23.980  0 159 THR 1 O   1 ? 
ATOM   1255 C CB  . THR A 1 157 ? 5.840   4.519   -17.720 0.330 25.960  0 159 THR 1 CB  1 ? 
ATOM   1256 O OG1 . THR A 1 157 ? 5.997   5.899   -18.068 0.330 24.700  0 159 THR 1 OG1 1 ? 
ATOM   1257 C CG2 . THR A 1 157 ? 4.871   4.401   -16.562 0.330 27.090  0 159 THR 1 CG2 1 ? 
ATOM   1258 N N   . ALA A 1 158 ? 7.982   5.774   -16.110 0.330 24.070  0 160 ALA 1 N   1 ? 
ATOM   1259 C CA  . ALA A 1 158 ? 8.691   6.507   -15.044 0.330 24.470  0 160 ALA 1 CA  1 ? 
ATOM   1260 C C   . ALA A 1 158 ? 8.154   7.931   -14.965 0.330 23.810  0 160 ALA 1 C   1 ? 
ATOM   1261 O O   . ALA A 1 158 ? 7.740   8.471   -16.008 0.330 25.300  0 160 ALA 1 O   1 ? 
ATOM   1262 C CB  . ALA A 1 158 ? 10.173  6.509   -15.325 0.330 26.220  0 160 ALA 1 CB  1 ? 
ATOM   1263 N N   . LEU A 1 159 ? 8.160   8.494   -13.759 0.330 23.270  0 161 LEU 1 N   1 ? 
ATOM   1264 C CA  . LEU A 1 159 ? 7.976   9.945   -13.510 0.330 23.330  0 161 LEU 1 CA  1 ? 
ATOM   1265 C C   . LEU A 1 159 ? 9.360   10.583  -13.438 0.330 22.220  0 161 LEU 1 C   1 ? 
ATOM   1266 O O   . LEU A 1 159 ? 10.224  10.046  -12.709 0.330 22.920  0 161 LEU 1 O   1 ? 
ATOM   1267 C CB  . LEU A 1 159 ? 7.215   10.138  -12.194 0.330 24.150  0 161 LEU 1 CB  1 ? 
ATOM   1268 C CG  . LEU A 1 159 ? 5.728   9.804   -12.232 0.330 24.240  0 161 LEU 1 CG  1 ? 
ATOM   1269 C CD1 . LEU A 1 159 ? 5.277   9.218   -10.905 0.330 25.220  0 161 LEU 1 CD1 1 ? 
ATOM   1270 C CD2 . LEU A 1 159 ? 4.910   11.028  -12.588 0.330 23.790  0 161 LEU 1 CD2 1 ? 
ATOM   1271 N N   . LEU A 1 160 ? 9.578   11.648  -14.208 0.330 22.960  0 162 LEU 1 N   1 ? 
ATOM   1272 C CA  . LEU A 1 160 ? 10.778  12.514  -14.086 0.330 23.170  0 162 LEU 1 CA  1 ? 
ATOM   1273 C C   . LEU A 1 160 ? 10.666  13.296  -12.775 0.330 23.300  0 162 LEU 1 C   1 ? 
ATOM   1274 O O   . LEU A 1 160 ? 9.596   13.886  -12.526 0.330 23.140  0 162 LEU 1 O   1 ? 
ATOM   1275 C CB  . LEU A 1 160 ? 10.866  13.455  -15.288 0.330 23.370  0 162 LEU 1 CB  1 ? 
ATOM   1276 C CG  . LEU A 1 160 ? 12.037  14.438  -15.262 0.330 24.070  0 162 LEU 1 CG  1 ? 
ATOM   1277 C CD1 . LEU A 1 160 ? 13.365  13.711  -15.387 0.330 24.800  0 162 LEU 1 CD1 1 ? 
ATOM   1278 C CD2 . LEU A 1 160 ? 11.889  15.471  -16.363 0.330 24.890  0 162 LEU 1 CD2 1 ? 
ATOM   1279 N N   . LEU A 1 161 ? 11.720  13.267  -11.960 0.330 22.560  0 163 LEU 1 N   1 ? 
ATOM   1280 C CA  . LEU A 1 161 ? 11.786  13.973  -10.655 0.330 24.000  0 163 LEU 1 CA  1 ? 
ATOM   1281 C C   . LEU A 1 161 ? 12.698  15.196  -10.765 0.330 24.400  0 163 LEU 1 C   1 ? 
ATOM   1282 O O   . LEU A 1 161 ? 13.631  15.172  -11.582 0.330 24.240  0 163 LEU 1 O   1 ? 
ATOM   1283 C CB  . LEU A 1 161 ? 12.352  13.031  -9.595  0.330 23.900  0 163 LEU 1 CB  1 ? 
ATOM   1284 C CG  . LEU A 1 161 ? 11.616  11.714  -9.399  0.330 24.670  0 163 LEU 1 CG  1 ? 
ATOM   1285 C CD1 . LEU A 1 161 ? 12.268  10.936  -8.273  0.330 25.380  0 163 LEU 1 CD1 1 ? 
ATOM   1286 C CD2 . LEU A 1 161 ? 10.135  11.951  -9.112  0.330 25.270  0 163 LEU 1 CD2 1 ? 
ATOM   1287 N N   . GLU A 1 162 ? 12.467  16.196  -9.916  0.330 25.790  0 164 GLU 1 N   1 ? 
ATOM   1288 C CA  . GLU A 1 162 ? 13.455  17.265  -9.609  0.330 28.090  0 164 GLU 1 CA  1 ? 
ATOM   1289 C C   . GLU A 1 162 ? 14.848  16.634  -9.523  0.330 27.740  0 164 GLU 1 C   1 ? 
ATOM   1290 O O   . GLU A 1 162 ? 14.988  15.615  -8.822  0.330 29.040  0 164 GLU 1 O   1 ? 
ATOM   1291 C CB  . GLU A 1 162 ? 13.100  17.945  -8.282  0.330 28.800  0 164 GLU 1 CB  1 ? 
ATOM   1292 C CG  . GLU A 1 162 ? 12.084  19.062  -8.411  0.330 31.400  0 164 GLU 1 CG  1 ? 
ATOM   1293 C CD  . GLU A 1 162 ? 11.680  19.721  -7.097  0.330 32.410  0 164 GLU 1 CD  1 ? 
ATOM   1294 O OE1 . GLU A 1 162 ? 12.572  19.917  -6.227  0.330 32.440  0 164 GLU 1 OE1 1 ? 
ATOM   1295 O OE2 . GLU A 1 162 ? 10.471  20.040  -6.943  0.330 31.950  0 164 GLU 1 OE2 1 ? 
ATOM   1296 N N   . GLY A 1 163 ? 15.838  17.196  -10.219 0.330 29.540  0 165 GLY 1 N   1 ? 
ATOM   1297 C CA  . GLY A 1 163 ? 17.245  16.766  -10.098 0.330 29.780  0 165 GLY 1 CA  1 ? 
ATOM   1298 C C   . GLY A 1 163 ? 17.606  15.601  -11.012 0.330 28.960  0 165 GLY 1 C   1 ? 
ATOM   1299 O O   . GLY A 1 163 ? 18.498  14.801  -10.641 0.330 29.000  0 165 GLY 1 O   1 ? 
ATOM   1300 N N   . ASN A 1 164 ? 16.972  15.507  -12.178 0.330 31.300  0 166 ASN 1 N   1 ? 
ATOM   1301 C CA  . ASN A 1 164 ? 17.458  14.643  -13.294 0.330 32.240  0 166 ASN 1 CA  1 ? 
ATOM   1302 C C   . ASN A 1 164 ? 17.203  13.160  -12.995 0.330 29.820  0 166 ASN 1 C   1 ? 
ATOM   1303 O O   . ASN A 1 164 ? 17.801  12.327  -13.689 0.330 31.810  0 166 ASN 1 O   1 ? 
ATOM   1304 C CB  . ASN A 1 164 ? 18.973  14.782  -13.507 0.330 34.420  0 166 ASN 1 CB  1 ? 
ATOM   1305 C CG  . ASN A 1 164 ? 19.443  16.202  -13.746 0.330 35.240  0 166 ASN 1 CG  1 ? 
ATOM   1306 O OD1 . ASN A 1 164 ? 18.657  17.061  -14.129 0.330 37.770  0 166 ASN 1 OD1 1 ? 
ATOM   1307 N ND2 . ASN A 1 164 ? 20.731  16.447  -13.544 0.330 33.840  0 166 ASN 1 ND2 1 ? 
ATOM   1308 N N   . ALA A 1 165 ? 16.421  12.833  -11.963 0.330 29.250  0 167 ALA 1 N   1 ? 
ATOM   1309 C CA  . ALA A 1 165 ? 16.201  11.435  -11.526 0.330 29.180  0 167 ALA 1 CA  1 ? 
ATOM   1310 C C   . ALA A 1 165 ? 14.856  10.937  -12.074 0.330 28.640  0 167 ALA 1 C   1 ? 
ATOM   1311 O O   . ALA A 1 165 ? 14.020  11.770  -12.469 0.330 26.860  0 167 ALA 1 O   1 ? 
ATOM   1312 C CB  . ALA A 1 165 ? 16.290  11.326  -10.023 0.330 30.090  0 167 ALA 1 CB  1 ? 
ATOM   1313 N N   . HIS A 1 166 ? 14.690  9.617   -12.166 0.330 28.100  0 168 HIS 1 N   1 ? 
ATOM   1314 C CA  . HIS A 1 166 ? 13.432  8.962   -12.600 0.330 26.620  0 168 HIS 1 CA  1 ? 
ATOM   1315 C C   . HIS A 1 166 ? 12.900  8.113   -11.445 0.330 26.400  0 168 HIS 1 C   1 ? 
ATOM   1316 O O   . HIS A 1 166 ? 13.715  7.652   -10.617 0.330 27.990  0 168 HIS 1 O   1 ? 
ATOM   1317 C CB  . HIS A 1 166 ? 13.645  8.132   -13.872 0.330 26.270  0 168 HIS 1 CB  1 ? 
ATOM   1318 C CG  . HIS A 1 166 ? 13.613  8.939   -15.120 0.330 27.180  0 168 HIS 1 CG  1 ? 
ATOM   1319 N ND1 . HIS A 1 166 ? 14.760  9.256   -15.820 0.330 27.590  0 168 HIS 1 ND1 1 ? 
ATOM   1320 C CD2 . HIS A 1 166 ? 12.583  9.493   -15.797 0.330 27.560  0 168 HIS 1 CD2 1 ? 
ATOM   1321 C CE1 . HIS A 1 166 ? 14.436  9.972   -16.880 0.330 28.100  0 168 HIS 1 CE1 1 ? 
ATOM   1322 N NE2 . HIS A 1 166 ? 13.106  10.136  -16.887 0.330 27.360  0 168 HIS 1 NE2 1 ? 
ATOM   1323 N N   . TYR A 1 167 ? 11.581  7.937   -11.411 0.330 25.890  0 169 TYR 1 N   1 ? 
ATOM   1324 C CA  . TYR A 1 167 ? 10.820  7.163   -10.401 0.330 24.930  0 169 TYR 1 CA  1 ? 
ATOM   1325 C C   . TYR A 1 167 ? 9.906   6.201   -11.162 0.330 25.800  0 169 TYR 1 C   1 ? 
ATOM   1326 O O   . TYR A 1 167 ? 8.931   6.682   -11.781 0.330 23.500  0 169 TYR 1 O   1 ? 
ATOM   1327 C CB  . TYR A 1 167 ? 10.060  8.148   -9.517  0.330 24.460  0 169 TYR 1 CB  1 ? 
ATOM   1328 C CG  . TYR A 1 167 ? 9.163   7.551   -8.467  0.330 24.750  0 169 TYR 1 CG  1 ? 
ATOM   1329 C CD1 . TYR A 1 167 ? 9.674   6.757   -7.454  0.330 24.090  0 169 TYR 1 CD1 1 ? 
ATOM   1330 C CD2 . TYR A 1 167 ? 7.810   7.834   -8.452  0.330 23.640  0 169 TYR 1 CD2 1 ? 
ATOM   1331 C CE1 . TYR A 1 167 ? 8.860   6.244   -6.464  0.330 24.300  0 169 TYR 1 CE1 1 ? 
ATOM   1332 C CE2 . TYR A 1 167 ? 6.982   7.325   -7.473  0.330 23.890  0 169 TYR 1 CE2 1 ? 
ATOM   1333 C CZ  . TYR A 1 167 ? 7.509   6.531   -6.473  0.330 23.680  0 169 TYR 1 CZ  1 ? 
ATOM   1334 O OH  . TYR A 1 167 ? 6.694   6.038   -5.504  0.330 23.700  0 169 TYR 1 OH  1 ? 
ATOM   1335 N N   . ARG A 1 168 ? 10.243  4.906   -11.148 0.330 25.620  0 170 ARG 1 N   1 ? 
ATOM   1336 C CA  . ARG A 1 168 ? 9.750   3.898   -12.121 0.330 27.600  0 170 ARG 1 CA  1 ? 
ATOM   1337 C C   . ARG A 1 168 ? 8.340   3.421   -11.751 0.330 26.410  0 170 ARG 1 C   1 ? 
ATOM   1338 O O   . ARG A 1 168 ? 8.071   3.183   -10.552 0.330 26.620  0 170 ARG 1 O   1 ? 
ATOM   1339 C CB  . ARG A 1 168 ? 10.740  2.736   -12.220 0.330 31.260  0 170 ARG 1 CB  1 ? 
ATOM   1340 C CG  . ARG A 1 168 ? 11.821  2.924   -13.273 0.330 34.960  0 170 ARG 1 CG  1 ? 
ATOM   1341 C CD  . ARG A 1 168 ? 11.390  2.440   -14.657 0.330 41.790  0 170 ARG 1 CD  1 ? 
ATOM   1342 N NE  . ARG A 1 168 ? 11.289  0.981   -14.764 0.330 44.840  0 170 ARG 1 NE  1 ? 
ATOM   1343 C CZ  . ARG A 1 168 ? 10.149  0.294   -14.869 0.330 45.260  0 170 ARG 1 CZ  1 ? 
ATOM   1344 N NH1 . ARG A 1 168 ? 8.987   0.924   -14.900 0.330 41.990  0 170 ARG 1 NH1 1 ? 
ATOM   1345 N NH2 . ARG A 1 168 ? 10.177  -1.028  -14.943 0.330 47.540  0 170 ARG 1 NH2 1 ? 
ATOM   1346 N N   . CYS A 1 169 ? 7.498   3.291   -12.782 0.330 26.310  0 171 CYS 1 N   1 ? 
ATOM   1347 C CA  . CYS A 1 169 ? 6.073   2.864   -12.772 0.330 27.230  0 171 CYS 1 CA  1 ? 
ATOM   1348 C C   . CYS A 1 169 ? 5.913   1.555   -13.551 0.330 26.640  0 171 CYS 1 C   1 ? 
ATOM   1349 O O   . CYS A 1 169 ? 6.334   1.546   -14.714 0.330 26.720  0 171 CYS 1 O   1 ? 
ATOM   1350 C CB  . CYS A 1 169 ? 5.178   3.850   -13.518 0.330 28.610  0 171 CYS 1 CB  1 ? 
ATOM   1351 S SG  . CYS A 1 169 ? 3.436   3.351   -13.484 0.330 33.490  0 171 CYS 1 SG  1 ? 
ATOM   1352 N N   . ASP A 1 170 ? 5.250   0.542   -12.985 0.330 24.760  0 172 ASP 1 N   1 ? 
ATOM   1353 C CA  . ASP A 1 170 ? 4.679   -0.584  -13.774 0.330 24.180  0 172 ASP 1 CA  1 ? 
ATOM   1354 C C   . ASP A 1 170 ? 3.152   -0.578  -13.616 0.330 23.990  0 172 ASP 1 C   1 ? 
ATOM   1355 O O   . ASP A 1 170 ? 2.679   -0.860  -12.493 0.330 23.710  0 172 ASP 1 O   1 ? 
ATOM   1356 C CB  . ASP A 1 170 ? 5.293   -1.926  -13.370 0.330 24.590  0 172 ASP 1 CB  1 ? 
ATOM   1357 C CG  . ASP A 1 170 ? 6.801   -1.990  -13.555 0.330 25.270  0 172 ASP 1 CG  1 ? 
ATOM   1358 O OD1 . ASP A 1 170 ? 7.273   -1.633  -14.657 0.330 27.100  0 172 ASP 1 OD1 1 ? 
ATOM   1359 O OD2 . ASP A 1 170 ? 7.489   -2.398  -12.605 0.330 23.950  0 172 ASP 1 OD2 1 ? 
ATOM   1360 N N   . PHE A 1 171 ? 2.415   -0.266  -14.692 0.330 23.820  0 173 PHE 1 N   1 ? 
ATOM   1361 C CA  . PHE A 1 171 ? 0.930   -0.369  -14.756 0.330 24.240  0 173 PHE 1 CA  1 ? 
ATOM   1362 C C   . PHE A 1 171 ? 0.539   -1.722  -15.353 0.330 23.660  0 173 PHE 1 C   1 ? 
ATOM   1363 O O   . PHE A 1 171 ? 1.192   -2.163  -16.313 0.330 23.890  0 173 PHE 1 O   1 ? 
ATOM   1364 C CB  . PHE A 1 171 ? 0.241   0.636   -15.692 0.330 24.340  0 173 PHE 1 CB  1 ? 
ATOM   1365 C CG  . PHE A 1 171 ? 0.653   2.082   -15.646 0.330 25.290  0 173 PHE 1 CG  1 ? 
ATOM   1366 C CD1 . PHE A 1 171 ? 1.172   2.656   -14.497 0.330 24.820  0 173 PHE 1 CD1 1 ? 
ATOM   1367 C CD2 . PHE A 1 171 ? 0.479   2.883   -16.769 0.330 25.050  0 173 PHE 1 CD2 1 ? 
ATOM   1368 C CE1 . PHE A 1 171 ? 1.526   3.999   -14.483 0.330 26.000  0 173 PHE 1 CE1 1 ? 
ATOM   1369 C CE2 . PHE A 1 171 ? 0.836   4.222   -16.750 0.330 25.450  0 173 PHE 1 CE2 1 ? 
ATOM   1370 C CZ  . PHE A 1 171 ? 1.373   4.774   -15.612 0.330 24.970  0 173 PHE 1 CZ  1 ? 
ATOM   1371 N N   . ARG A 1 172 ? -0.536  -2.317  -14.836 0.330 24.360  0 174 ARG 1 N   1 ? 
ATOM   1372 C CA  . ARG A 1 172 ? -1.302  -3.376  -15.542 0.330 24.800  0 174 ARG 1 CA  1 ? 
ATOM   1373 C C   . ARG A 1 172 ? -2.790  -3.014  -15.515 0.330 23.900  0 174 ARG 1 C   1 ? 
ATOM   1374 O O   . ARG A 1 172 ? -3.363  -2.902  -14.423 0.330 24.050  0 174 ARG 1 O   1 ? 
ATOM   1375 C CB  . ARG A 1 172 ? -1.108  -4.766  -14.930 0.330 25.930  0 174 ARG 1 CB  1 ? 
ATOM   1376 C CG  . ARG A 1 172 ? -2.063  -5.792  -15.527 0.330 27.480  0 174 ARG 1 CG  1 ? 
ATOM   1377 C CD  . ARG A 1 172 ? -1.569  -7.223  -15.449 0.330 29.060  0 174 ARG 1 CD  1 ? 
ATOM   1378 N NE  . ARG A 1 172 ? -0.233  -7.329  -15.998 0.330 29.600  0 174 ARG 1 NE  1 ? 
ATOM   1379 C CZ  . ARG A 1 172 ? 0.595   -8.324  -15.725 0.330 30.640  0 174 ARG 1 CZ  1 ? 
ATOM   1380 N NH1 . ARG A 1 172 ? 0.198   -9.295  -14.923 0.330 29.560  0 174 ARG 1 NH1 1 ? 
ATOM   1381 N NH2 . ARG A 1 172 ? 1.801   -8.345  -16.251 0.330 29.040  0 174 ARG 1 NH2 1 ? 
ATOM   1382 N N   . THR A 1 173 ? -3.406  -2.877  -16.683 0.330 23.360  0 175 THR 1 N   1 ? 
ATOM   1383 C CA  . THR A 1 173 ? -4.842  -2.521  -16.817 0.330 23.430  0 175 THR 1 CA  1 ? 
ATOM   1384 C C   . THR A 1 173 ? -5.580  -3.674  -17.490 0.330 23.860  0 175 THR 1 C   1 ? 
ATOM   1385 O O   . THR A 1 173 ? -5.079  -4.171  -18.511 0.330 24.910  0 175 THR 1 O   1 ? 
ATOM   1386 C CB  . THR A 1 173 ? -5.029  -1.233  -17.628 0.330 23.500  0 175 THR 1 CB  1 ? 
ATOM   1387 O OG1 . THR A 1 173 ? -4.166  -0.241  -17.077 0.330 23.400  0 175 THR 1 OG1 1 ? 
ATOM   1388 C CG2 . THR A 1 173 ? -6.455  -0.732  -17.618 0.330 23.740  0 175 THR 1 CG2 1 ? 
ATOM   1389 N N   . THR A 1 174 ? -6.724  -4.067  -16.935 0.330 23.450  0 176 THR 1 N   1 ? 
ATOM   1390 C CA  . THR A 1 174 ? -7.674  -5.017  -17.556 0.330 24.270  0 176 THR 1 CA  1 ? 
ATOM   1391 C C   . THR A 1 174 ? -8.900  -4.229  -18.026 0.330 25.280  0 176 THR 1 C   1 ? 
ATOM   1392 O O   . THR A 1 174 ? -9.463  -3.431  -17.233 0.330 23.670  0 176 THR 1 O   1 ? 
ATOM   1393 C CB  . THR A 1 174 ? -8.014  -6.173  -16.608 0.330 25.010  0 176 THR 1 CB  1 ? 
ATOM   1394 O OG1 . THR A 1 174 ? -8.438  -5.613  -15.366 0.330 26.380  0 176 THR 1 OG1 1 ? 
ATOM   1395 C CG2 . THR A 1 174 ? -6.842  -7.097  -16.365 0.330 25.880  0 176 THR 1 CG2 1 ? 
ATOM   1396 N N   . TYR A 1 175 ? -9.285  -4.445  -19.280 0.330 25.180  0 177 TYR 1 N   1 ? 
ATOM   1397 C CA  . TYR A 1 175 ? -10.401 -3.741  -19.960 0.330 25.800  0 177 TYR 1 CA  1 ? 
ATOM   1398 C C   . TYR A 1 175 ? -11.531 -4.742  -20.218 0.330 25.990  0 177 TYR 1 C   1 ? 
ATOM   1399 O O   . TYR A 1 175 ? -11.240 -5.851  -20.705 0.330 25.680  0 177 TYR 1 O   1 ? 
ATOM   1400 C CB  . TYR A 1 175 ? -9.902  -3.121  -21.264 0.330 24.720  0 177 TYR 1 CB  1 ? 
ATOM   1401 C CG  . TYR A 1 175 ? -8.738  -2.166  -21.140 0.330 24.950  0 177 TYR 1 CG  1 ? 
ATOM   1402 C CD1 . TYR A 1 175 ? -8.944  -0.826  -20.862 0.330 24.800  0 177 TYR 1 CD1 1 ? 
ATOM   1403 C CD2 . TYR A 1 175 ? -7.432  -2.579  -21.354 0.330 25.190  0 177 TYR 1 CD2 1 ? 
ATOM   1404 C CE1 . TYR A 1 175 ? -7.893  0.070   -20.788 0.330 23.510  0 177 TYR 1 CE1 1 ? 
ATOM   1405 C CE2 . TYR A 1 175 ? -6.363  -1.697  -21.276 0.330 24.960  0 177 TYR 1 CE2 1 ? 
ATOM   1406 C CZ  . TYR A 1 175 ? -6.596  -0.361  -20.991 0.330 25.460  0 177 TYR 1 CZ  1 ? 
ATOM   1407 O OH  . TYR A 1 175 ? -5.573  0.543   -20.914 0.330 24.540  0 177 TYR 1 OH  1 ? 
ATOM   1408 N N   . LYS A 1 176 ? -12.777 -4.367  -19.916 0.330 25.800  0 178 LYS 1 N   1 ? 
ATOM   1409 C CA  . LYS A 1 176 ? -13.955 -5.253  -20.100 0.330 27.990  0 178 LYS 1 CA  1 ? 
ATOM   1410 C C   . LYS A 1 176 ? -15.148 -4.448  -20.623 0.330 26.610  0 178 LYS 1 C   1 ? 
ATOM   1411 O O   . LYS A 1 176 ? -15.654 -3.566  -19.887 0.330 24.900  0 178 LYS 1 O   1 ? 
ATOM   1412 C CB  . LYS A 1 176 ? -14.306 -5.958  -18.787 0.330 30.590  0 178 LYS 1 CB  1 ? 
ATOM   1413 C CG  . LYS A 1 176 ? -13.204 -6.846  -18.230 0.330 34.780  0 178 LYS 1 CG  1 ? 
ATOM   1414 C CD  . LYS A 1 176 ? -13.678 -7.837  -17.177 0.330 36.190  0 178 LYS 1 CD  1 ? 
ATOM   1415 C CE  . LYS A 1 176 ? -12.570 -8.744  -16.677 0.330 37.740  0 178 LYS 1 CE  1 ? 
ATOM   1416 N NZ  . LYS A 1 176 ? -13.104 -10.013 -16.113 0.330 38.780  0 178 LYS 1 NZ  1 ? 
ATOM   1417 N N   . ALA A 1 177 ? -15.584 -4.766  -21.845 0.330 27.420  0 179 ALA 1 N   1 ? 
ATOM   1418 C CA  . ALA A 1 177 ? -16.840 -4.277  -22.457 0.330 28.390  0 179 ALA 1 CA  1 ? 
ATOM   1419 C C   . ALA A 1 177 ? -18.024 -4.743  -21.600 0.330 29.860  0 179 ALA 1 C   1 ? 
ATOM   1420 O O   . ALA A 1 177 ? -17.955 -5.872  -21.069 0.330 29.380  0 179 ALA 1 O   1 ? 
ATOM   1421 C CB  . ALA A 1 177 ? -16.942 -4.794  -23.871 0.330 29.200  0 179 ALA 1 CB  1 ? 
ATOM   1422 N N   . LYS A 1 178 ? -19.058 -3.909  -21.456 0.330 30.530  0 180 LYS 1 N   1 ? 
ATOM   1423 C CA  . LYS A 1 178 ? -20.311 -4.258  -20.734 0.330 33.080  0 180 LYS 1 CA  1 ? 
ATOM   1424 C C   . LYS A 1 178 ? -21.091 -5.292  -21.554 0.330 33.570  0 180 LYS 1 C   1 ? 
ATOM   1425 O O   . LYS A 1 178 ? -21.720 -6.171  -20.948 0.330 35.600  0 180 LYS 1 O   1 ? 
ATOM   1426 C CB  . LYS A 1 178 ? -21.177 -3.020  -20.486 0.330 34.970  0 180 LYS 1 CB  1 ? 
ATOM   1427 C CG  . LYS A 1 178 ? -21.078 -2.442  -19.078 0.330 37.350  0 180 LYS 1 CG  1 ? 
ATOM   1428 C CD  . LYS A 1 178 ? -22.080 -1.334  -18.790 0.330 38.970  0 180 LYS 1 CD  1 ? 
ATOM   1429 C CE  . LYS A 1 178 ? -23.528 -1.763  -18.926 0.330 39.350  0 180 LYS 1 CE  1 ? 
ATOM   1430 N NZ  . LYS A 1 178 ? -24.042 -2.393  -17.687 0.330 38.370  0 180 LYS 1 NZ  1 ? 
ATOM   1431 N N   . GLU A 1 179 ? -21.036 -5.173  -22.881 0.330 35.030  0 181 GLU 1 N   1 ? 
ATOM   1432 C CA  . GLU A 1 179 ? -21.778 -6.023  -23.846 0.330 38.640  0 181 GLU 1 CA  1 ? 
ATOM   1433 C C   . GLU A 1 179 ? -20.961 -7.283  -24.121 0.330 39.420  0 181 GLU 1 C   1 ? 
ATOM   1434 O O   . GLU A 1 179 ? -19.868 -7.164  -24.689 0.330 38.180  0 181 GLU 1 O   1 ? 
ATOM   1435 C CB  . GLU A 1 179 ? -22.036 -5.251  -25.142 0.330 41.150  0 181 GLU 1 CB  1 ? 
ATOM   1436 C CG  . GLU A 1 179 ? -23.156 -5.817  -25.999 0.330 43.570  0 181 GLU 1 CG  1 ? 
ATOM   1437 C CD  . GLU A 1 179 ? -23.431 -5.004  -27.258 0.330 44.570  0 181 GLU 1 CD  1 ? 
ATOM   1438 O OE1 . GLU A 1 179 ? -24.601 -4.624  -27.483 0.330 44.420  0 181 GLU 1 OE1 1 ? 
ATOM   1439 O OE2 . GLU A 1 179 ? -22.471 -4.759  -28.018 0.330 42.790  0 181 GLU 1 OE2 1 ? 
ATOM   1440 N N   . LYS A 1 180 ? -21.478 -8.441  -23.706 0.330 44.270  0 182 LYS 1 N   1 ? 
ATOM   1441 C CA  . LYS A 1 180 ? -20.918 -9.775  -24.037 0.330 44.120  0 182 LYS 1 CA  1 ? 
ATOM   1442 C C   . LYS A 1 180 ? -20.773 -9.846  -25.559 0.330 42.830  0 182 LYS 1 C   1 ? 
ATOM   1443 O O   . LYS A 1 180 ? -21.658 -9.310  -26.256 0.330 42.480  0 182 LYS 1 O   1 ? 
ATOM   1444 C CB  . LYS A 1 180 ? -21.835 -10.884 -23.504 0.330 47.720  0 182 LYS 1 CB  1 ? 
ATOM   1445 C CG  . LYS A 1 180 ? -23.178 -11.031 -24.220 0.330 48.890  0 182 LYS 1 CG  1 ? 
ATOM   1446 C CD  . LYS A 1 180 ? -24.232 -10.013 -23.812 0.330 50.290  0 182 LYS 1 CD  1 ? 
ATOM   1447 C CE  . LYS A 1 180 ? -24.405 -8.898  -24.821 0.330 50.450  0 182 LYS 1 CE  1 ? 
ATOM   1448 N NZ  . LYS A 1 180 ? -25.425 -7.919  -24.383 0.330 50.540  0 182 LYS 1 NZ  1 ? 
ATOM   1449 N N   . GLY A 1 181 ? -19.686 -10.451 -26.048 0.330 41.320  0 183 GLY 1 N   1 ? 
ATOM   1450 C CA  . GLY A 1 181 ? -19.479 -10.716 -27.484 0.330 40.120  0 183 GLY 1 CA  1 ? 
ATOM   1451 C C   . GLY A 1 181 ? -19.051 -9.482  -28.265 0.330 39.580  0 183 GLY 1 C   1 ? 
ATOM   1452 O O   . GLY A 1 181 ? -19.371 -9.411  -29.461 0.330 41.270  0 183 GLY 1 O   1 ? 
ATOM   1453 N N   . VAL A 1 182 ? -18.359 -8.530  -27.634 0.330 37.190  0 184 VAL 1 N   1 ? 
ATOM   1454 C CA  . VAL A 1 182 ? -17.467 -7.581  -28.360 0.330 34.930  0 184 VAL 1 CA  1 ? 
ATOM   1455 C C   . VAL A 1 182 ? -16.139 -8.313  -28.563 0.330 33.460  0 184 VAL 1 C   1 ? 
ATOM   1456 O O   . VAL A 1 182 ? -15.498 -8.634  -27.550 0.330 32.120  0 184 VAL 1 O   1 ? 
ATOM   1457 C CB  . VAL A 1 182 ? -17.257 -6.257  -27.604 0.330 36.730  0 184 VAL 1 CB  1 ? 
ATOM   1458 C CG1 . VAL A 1 182 ? -16.257 -5.362  -28.325 0.330 36.720  0 184 VAL 1 CG1 1 ? 
ATOM   1459 C CG2 . VAL A 1 182 ? -18.568 -5.529  -27.367 0.330 37.320  0 184 VAL 1 CG2 1 ? 
ATOM   1460 N N   . LYS A 1 183 ? -15.764 -8.591  -29.815 0.330 31.820  0 185 LYS 1 N   1 ? 
ATOM   1461 C CA  . LYS A 1 183 ? -14.590 -9.434  -30.161 0.330 32.250  0 185 LYS 1 CA  1 ? 
ATOM   1462 C C   . LYS A 1 183 ? -13.308 -8.783  -29.640 0.330 31.590  0 185 LYS 1 C   1 ? 
ATOM   1463 O O   . LYS A 1 183 ? -13.090 -7.577  -29.888 0.330 32.110  0 185 LYS 1 O   1 ? 
ATOM   1464 C CB  . LYS A 1 183 ? -14.546 -9.673  -31.673 0.330 34.710  0 185 LYS 1 CB  1 ? 
ATOM   1465 C CG  . LYS A 1 183 ? -15.817 -10.288 -32.247 0.330 36.480  0 185 LYS 1 CG  1 ? 
ATOM   1466 C CD  . LYS A 1 183 ? -16.045 -11.727 -31.815 0.330 39.280  0 185 LYS 1 CD  1 ? 
ATOM   1467 C CE  . LYS A 1 183 ? -14.985 -12.678 -32.338 0.330 41.150  0 185 LYS 1 CE  1 ? 
ATOM   1468 N NZ  . LYS A 1 183 ? -15.261 -14.083 -31.946 0.330 42.230  0 185 LYS 1 NZ  1 ? 
ATOM   1469 N N   . LEU A 1 184 ? -12.502 -9.563  -28.924 0.330 30.740  0 186 LEU 1 N   1 ? 
ATOM   1470 C CA  . LEU A 1 184 ? -11.151 -9.163  -28.464 0.330 30.300  0 186 LEU 1 CA  1 ? 
ATOM   1471 C C   . LEU A 1 184 ? -10.297 -8.835  -29.681 0.330 30.120  0 186 LEU 1 C   1 ? 
ATOM   1472 O O   . LEU A 1 184 ? -10.428 -9.455  -30.738 0.330 27.320  0 186 LEU 1 O   1 ? 
ATOM   1473 C CB  . LEU A 1 184 ? -10.542 -10.304 -27.650 0.330 30.880  0 186 LEU 1 CB  1 ? 
ATOM   1474 C CG  . LEU A 1 184 ? -11.271 -10.651 -26.356 0.330 32.050  0 186 LEU 1 CG  1 ? 
ATOM   1475 C CD1 . LEU A 1 184 ? -10.736 -11.950 -25.776 0.330 32.890  0 186 LEU 1 CD1 1 ? 
ATOM   1476 C CD2 . LEU A 1 184 ? -11.147 -9.527  -25.342 0.330 33.280  0 186 LEU 1 CD2 1 ? 
ATOM   1477 N N   . PRO A 1 185 ? -9.417  -7.817  -29.570 0.330 28.370  0 187 PRO 1 N   1 ? 
ATOM   1478 C CA  . PRO A 1 185 ? -8.464  -7.507  -30.621 0.330 27.490  0 187 PRO 1 CA  1 ? 
ATOM   1479 C C   . PRO A 1 185 ? -7.264  -8.454  -30.531 0.330 26.960  0 187 PRO 1 C   1 ? 
ATOM   1480 O O   . PRO A 1 185 ? -7.123  -9.129  -29.525 0.330 28.160  0 187 PRO 1 O   1 ? 
ATOM   1481 C CB  . PRO A 1 185 ? -8.059  -6.063  -30.284 0.330 27.320  0 187 PRO 1 CB  1 ? 
ATOM   1482 C CG  . PRO A 1 185 ? -8.122  -6.028  -28.779 0.330 26.910  0 187 PRO 1 CG  1 ? 
ATOM   1483 C CD  . PRO A 1 185 ? -9.299  -6.906  -28.418 0.330 28.310  0 187 PRO 1 CD  1 ? 
ATOM   1484 N N   . GLY A 1 186 ? -6.438  -8.479  -31.574 0.330 26.780  0 188 GLY 1 N   1 ? 
ATOM   1485 C CA  . GLY A 1 186 ? -5.098  -9.082  -31.517 0.330 26.070  0 188 GLY 1 CA  1 ? 
ATOM   1486 C C   . GLY A 1 186 ? -4.159  -8.170  -30.745 0.330 25.250  0 188 GLY 1 C   1 ? 
ATOM   1487 O O   . GLY A 1 186 ? -4.408  -6.945  -30.710 0.330 26.020  0 188 GLY 1 O   1 ? 
ATOM   1488 N N   . ALA A 1 187 ? -3.129  -8.738  -30.134 0.330 24.180  0 189 ALA 1 N   1 ? 
ATOM   1489 C CA  . ALA A 1 187 ? -2.036  -7.988  -29.482 0.330 23.870  0 189 ALA 1 CA  1 ? 
ATOM   1490 C C   . ALA A 1 187 ? -1.692  -6.789  -30.366 0.330 23.310  0 189 ALA 1 C   1 ? 
ATOM   1491 O O   . ALA A 1 187 ? -1.873  -6.886  -31.600 0.330 22.560  0 189 ALA 1 O   1 ? 
ATOM   1492 C CB  . ALA A 1 187 ? -0.860  -8.901  -29.257 0.330 23.360  0 189 ALA 1 CB  1 ? 
ATOM   1493 N N   . HIS A 1 188 ? -1.263  -5.688  -29.746 0.330 22.610  0 190 HIS 1 N   1 ? 
ATOM   1494 C CA  . HIS A 1 188 ? -0.832  -4.435  -30.418 0.330 22.180  0 190 HIS 1 CA  1 ? 
ATOM   1495 C C   . HIS A 1 188 ? -0.228  -3.478  -29.378 0.330 21.910  0 190 HIS 1 C   1 ? 
ATOM   1496 O O   . HIS A 1 188 ? -0.013  -3.897  -28.214 0.330 21.230  0 190 HIS 1 O   1 ? 
ATOM   1497 C CB  . HIS A 1 188 ? -1.987  -3.799  -31.206 0.330 22.250  0 190 HIS 1 CB  1 ? 
ATOM   1498 C CG  . HIS A 1 188 ? -3.151  -3.353  -30.377 0.330 22.910  0 190 HIS 1 CG  1 ? 
ATOM   1499 N ND1 . HIS A 1 188 ? -4.073  -4.243  -29.857 0.330 21.990  0 190 HIS 1 ND1 1 ? 
ATOM   1500 C CD2 . HIS A 1 188 ? -3.554  -2.119  -29.988 0.330 22.210  0 190 HIS 1 CD2 1 ? 
ATOM   1501 C CE1 . HIS A 1 188 ? -5.001  -3.574  -29.193 0.330 22.870  0 190 HIS 1 CE1 1 ? 
ATOM   1502 N NE2 . HIS A 1 188 ? -4.707  -2.273  -29.259 0.330 21.350  0 190 HIS 1 NE2 1 ? 
ATOM   1503 N N   . PHE A 1 189 ? 0.075   -2.257  -29.804 0.330 22.060  0 191 PHE 1 N   1 ? 
ATOM   1504 C CA  . PHE A 1 189 ? 0.713   -1.210  -28.970 0.330 23.550  0 191 PHE 1 CA  1 ? 
ATOM   1505 C C   . PHE A 1 189 ? -0.125  0.066   -29.028 0.330 23.590  0 191 PHE 1 C   1 ? 
ATOM   1506 O O   . PHE A 1 189 ? -0.767  0.319   -30.062 0.330 24.920  0 191 PHE 1 O   1 ? 
ATOM   1507 C CB  . PHE A 1 189 ? 2.129   -0.911  -29.463 0.330 25.030  0 191 PHE 1 CB  1 ? 
ATOM   1508 C CG  . PHE A 1 189 ? 3.044   -2.108  -29.502 0.330 27.140  0 191 PHE 1 CG  1 ? 
ATOM   1509 C CD1 . PHE A 1 189 ? 3.623   -2.594  -28.342 0.330 28.180  0 191 PHE 1 CD1 1 ? 
ATOM   1510 C CD2 . PHE A 1 189 ? 3.315   -2.751  -30.696 0.330 29.480  0 191 PHE 1 CD2 1 ? 
ATOM   1511 C CE1 . PHE A 1 189 ? 4.454   -3.702  -28.377 0.330 30.170  0 191 PHE 1 CE1 1 ? 
ATOM   1512 C CE2 . PHE A 1 189 ? 4.154   -3.851  -30.732 0.330 30.950  0 191 PHE 1 CE2 1 ? 
ATOM   1513 C CZ  . PHE A 1 189 ? 4.722   -4.325  -29.572 0.330 31.300  0 191 PHE 1 CZ  1 ? 
ATOM   1514 N N   . VAL A 1 190 ? -0.082  0.850   -27.951 0.330 23.080  0 192 VAL 1 N   1 ? 
ATOM   1515 C CA  . VAL A 1 190 ? -0.608  2.239   -27.905 0.330 22.370  0 192 VAL 1 CA  1 ? 
ATOM   1516 C C   . VAL A 1 190 ? 0.475   3.133   -27.296 0.330 22.870  0 192 VAL 1 C   1 ? 
ATOM   1517 O O   . VAL A 1 190 ? 0.814   2.941   -26.106 0.330 21.910  0 192 VAL 1 O   1 ? 
ATOM   1518 C CB  . VAL A 1 190 ? -1.921  2.321   -27.105 0.330 22.800  0 192 VAL 1 CB  1 ? 
ATOM   1519 C CG1 . VAL A 1 190 ? -2.532  3.717   -27.189 0.330 22.880  0 192 VAL 1 CG1 1 ? 
ATOM   1520 C CG2 . VAL A 1 190 ? -2.920  1.271   -27.551 0.330 22.580  0 192 VAL 1 CG2 1 ? 
ATOM   1521 N N   . ASP A 1 191 ? 0.987   4.075   -28.085 0.330 22.060  0 193 ASP 1 N   1 ? 
ATOM   1522 C CA  . ASP A 1 191 ? 1.924   5.124   -27.614 0.330 22.190  0 193 ASP 1 CA  1 ? 
ATOM   1523 C C   . ASP A 1 191 ? 1.104   6.213   -26.917 0.330 21.540  0 193 ASP 1 C   1 ? 
ATOM   1524 O O   . ASP A 1 191 ? 0.031   6.579   -27.445 0.330 20.030  0 193 ASP 1 O   1 ? 
ATOM   1525 C CB  . ASP A 1 191 ? 2.757   5.673   -28.770 0.330 23.140  0 193 ASP 1 CB  1 ? 
ATOM   1526 C CG  . ASP A 1 191 ? 3.807   4.696   -29.269 0.330 24.200  0 193 ASP 1 CG  1 ? 
ATOM   1527 O OD1 . ASP A 1 191 ? 3.750   3.504   -28.890 0.330 25.890  0 193 ASP 1 OD1 1 ? 
ATOM   1528 O OD2 . ASP A 1 191 ? 4.658   5.130   -30.056 0.330 28.030  0 193 ASP 1 OD2 1 ? 
ATOM   1529 N N   . HIS A 1 192 ? 1.585   6.701   -25.770 0.330 21.040  0 194 HIS 1 N   1 ? 
ATOM   1530 C CA  . HIS A 1 192 ? 0.867   7.688   -24.928 0.330 22.040  0 194 HIS 1 CA  1 ? 
ATOM   1531 C C   . HIS A 1 192 ? 1.732   8.935   -24.739 0.330 21.450  0 194 HIS 1 C   1 ? 
ATOM   1532 O O   . HIS A 1 192 ? 2.966   8.776   -24.602 0.330 21.070  0 194 HIS 1 O   1 ? 
ATOM   1533 C CB  . HIS A 1 192 ? 0.450   7.054   -23.600 0.330 22.750  0 194 HIS 1 CB  1 ? 
ATOM   1534 C CG  . HIS A 1 192 ? -0.640  6.046   -23.722 0.330 24.280  0 194 HIS 1 CG  1 ? 
ATOM   1535 N ND1 . HIS A 1 192 ? -1.982  6.392   -23.716 0.330 25.190  0 194 HIS 1 ND1 1 ? 
ATOM   1536 C CD2 . HIS A 1 192 ? -0.598  4.702   -23.817 0.330 24.280  0 194 HIS 1 CD2 1 ? 
ATOM   1537 C CE1 . HIS A 1 192 ? -2.710  5.297   -23.827 0.330 25.990  0 194 HIS 1 CE1 1 ? 
ATOM   1538 N NE2 . HIS A 1 192 ? -1.883  4.250   -23.885 0.330 23.820  0 194 HIS 1 NE2 1 ? 
ATOM   1539 N N   . CYS A 1 193 ? 1.088   10.110  -24.765 0.330 21.690  0 195 CYS 1 N   1 ? 
ATOM   1540 C CA  . CYS A 1 193 ? 1.690   11.457  -24.548 0.330 23.840  0 195 CYS 1 CA  1 ? 
ATOM   1541 C C   . CYS A 1 193 ? 0.843   12.252  -23.550 0.330 23.180  0 195 CYS 1 C   1 ? 
ATOM   1542 O O   . CYS A 1 193 ? 0.016   13.030  -24.034 0.330 25.430  0 195 CYS 1 O   1 ? 
ATOM   1543 C CB  . CYS A 1 193 ? 1.720   12.295  -25.823 0.330 24.490  0 195 CYS 1 CB  1 ? 
ATOM   1544 S SG  . CYS A 1 193 ? 2.287   13.976  -25.477 0.330 34.450  0 195 CYS 1 SG  1 ? 
ATOM   1545 N N   . ILE A 1 194 ? 1.032   12.094  -22.234 0.330 21.960  0 196 ILE 1 N   1 ? 
ATOM   1546 C CA  . ILE A 1 194 ? 0.193   12.805  -21.220 0.330 22.280  0 196 ILE 1 CA  1 ? 
ATOM   1547 C C   . ILE A 1 194 ? 0.977   13.981  -20.621 0.330 21.070  0 196 ILE 1 C   1 ? 
ATOM   1548 O O   . ILE A 1 194 ? 2.144   13.785  -20.232 0.330 20.430  0 196 ILE 1 O   1 ? 
ATOM   1549 C CB  . ILE A 1 194 ? -0.323  11.839  -20.132 0.330 22.270  0 196 ILE 1 CB  1 ? 
ATOM   1550 C CG1 . ILE A 1 194 ? -1.540  12.418  -19.409 0.330 22.910  0 196 ILE 1 CG1 1 ? 
ATOM   1551 C CG2 . ILE A 1 194 ? 0.787   11.470  -19.171 0.330 22.260  0 196 ILE 1 CG2 1 ? 
ATOM   1552 C CD1 . ILE A 1 194 ? -2.229  11.444  -18.468 0.330 23.210  0 196 ILE 1 CD1 1 ? 
ATOM   1553 N N   . GLU A 1 195 ? 0.342   15.154  -20.537 0.330 21.300  0 197 GLU 1 N   1 ? 
ATOM   1554 C CA  . GLU A 1 195 ? 0.978   16.400  -20.018 0.330 21.840  0 197 GLU 1 CA  1 ? 
ATOM   1555 C C   . GLU A 1 195 ? -0.037  17.256  -19.262 0.330 21.050  0 197 GLU 1 C   1 ? 
ATOM   1556 O O   . GLU A 1 195 ? -1.195  17.348  -19.707 0.330 21.130  0 197 GLU 1 O   1 ? 
ATOM   1557 C CB  . GLU A 1 195 ? 1.543   17.254  -21.153 0.330 22.790  0 197 GLU 1 CB  1 ? 
ATOM   1558 C CG  . GLU A 1 195 ? 2.709   16.617  -21.882 0.330 25.120  0 197 GLU 1 CG  1 ? 
ATOM   1559 C CD  . GLU A 1 195 ? 3.384   17.530  -22.903 0.330 24.030  0 197 GLU 1 CD  1 ? 
ATOM   1560 O OE1 . GLU A 1 195 ? 4.018   17.000  -23.817 0.330 23.460  0 197 GLU 1 OE1 1 ? 
ATOM   1561 O OE2 . GLU A 1 195 ? 3.249   18.765  -22.771 0.330 26.510  0 197 GLU 1 OE2 1 ? 
ATOM   1562 N N   . ILE A 1 196 ? 0.408   17.887  -18.174 0.330 20.770  0 198 ILE 1 N   1 ? 
ATOM   1563 C CA  . ILE A 1 196 ? -0.331  18.989  -17.496 0.330 21.550  0 198 ILE 1 CA  1 ? 
ATOM   1564 C C   . ILE A 1 196 ? -0.010  20.292  -18.236 0.330 22.170  0 198 ILE 1 C   1 ? 
ATOM   1565 O O   . ILE A 1 196 ? 1.163   20.692  -18.264 0.330 22.280  0 198 ILE 1 O   1 ? 
ATOM   1566 C CB  . ILE A 1 196 ? 0.022   19.070  -16.002 0.330 22.310  0 198 ILE 1 CB  1 ? 
ATOM   1567 C CG1 . ILE A 1 196 ? -0.462  17.827  -15.250 0.330 22.710  0 198 ILE 1 CG1 1 ? 
ATOM   1568 C CG2 . ILE A 1 196 ? -0.534  20.353  -15.407 0.330 22.140  0 198 ILE 1 CG2 1 ? 
ATOM   1569 C CD1 . ILE A 1 196 ? -0.094  17.816  -13.780 0.330 24.810  0 198 ILE 1 CD1 1 ? 
ATOM   1570 N N   . LEU A 1 197 ? -1.017  20.906  -18.843 0.330 22.660  0 199 LEU 1 N   1 ? 
ATOM   1571 C CA  . LEU A 1 197 ? -0.849  22.106  -19.703 0.330 23.890  0 199 LEU 1 CA  1 ? 
ATOM   1572 C C   . LEU A 1 197 ? -0.806  23.364  -18.830 0.330 23.820  0 199 LEU 1 C   1 ? 
ATOM   1573 O O   . LEU A 1 197 ? -0.080  24.303  -19.182 0.330 24.030  0 199 LEU 1 O   1 ? 
ATOM   1574 C CB  . LEU A 1 197 ? -2.021  22.164  -20.680 0.330 24.550  0 199 LEU 1 CB  1 ? 
ATOM   1575 C CG  . LEU A 1 197 ? -1.982  21.131  -21.805 0.330 24.180  0 199 LEU 1 CG  1 ? 
ATOM   1576 C CD1 . LEU A 1 197 ? -3.035  21.452  -22.848 0.330 24.740  0 199 LEU 1 CD1 1 ? 
ATOM   1577 C CD2 . LEU A 1 197 ? -0.607  21.062  -22.435 0.330 25.440  0 199 LEU 1 CD2 1 ? 
ATOM   1578 N N   . SER A 1 198 ? -1.573  23.386  -17.745 0.330 23.740  0 200 SER 1 N   1 ? 
ATOM   1579 C CA  . SER A 1 198 ? -1.589  24.502  -16.767 0.330 23.640  0 200 SER 1 CA  1 ? 
ATOM   1580 C C   . SER A 1 198 ? -2.096  24.005  -15.415 0.330 22.950  0 200 SER 1 C   1 ? 
ATOM   1581 O O   . SER A 1 198 ? -2.715  22.913  -15.362 0.330 23.070  0 200 SER 1 O   1 ? 
ATOM   1582 C CB  . SER A 1 198 ? -2.406  25.671  -17.259 0.330 23.880  0 200 SER 1 CB  1 ? 
ATOM   1583 O OG  . SER A 1 198 ? -3.712  25.254  -17.621 0.330 25.470  0 200 SER 1 OG  1 ? 
ATOM   1584 N N   . HIS A 1 199 ? -1.831  24.794  -14.374 0.330 22.430  0 201 HIS 1 N   1 ? 
ATOM   1585 C CA  . HIS A 1 199 ? -2.134  24.486  -12.956 0.330 22.700  0 201 HIS 1 CA  1 ? 
ATOM   1586 C C   . HIS A 1 199 ? -2.076  25.786  -12.148 0.330 24.070  0 201 HIS 1 C   1 ? 
ATOM   1587 O O   . HIS A 1 199 ? -1.388  26.732  -12.586 0.330 23.590  0 201 HIS 1 O   1 ? 
ATOM   1588 C CB  . HIS A 1 199 ? -1.128  23.470  -12.415 0.330 22.620  0 201 HIS 1 CB  1 ? 
ATOM   1589 C CG  . HIS A 1 199 ? 0.262   24.005  -12.372 0.330 24.480  0 201 HIS 1 CG  1 ? 
ATOM   1590 N ND1 . HIS A 1 199 ? 0.805   24.553  -11.225 0.330 24.300  0 201 HIS 1 ND1 1 ? 
ATOM   1591 C CD2 . HIS A 1 199 ? 1.213   24.098  -13.331 0.330 25.470  0 201 HIS 1 CD2 1 ? 
ATOM   1592 C CE1 . HIS A 1 199 ? 2.033   24.956  -11.477 0.330 25.550  0 201 HIS 1 CE1 1 ? 
ATOM   1593 N NE2 . HIS A 1 199 ? 2.307   24.685  -12.764 0.330 25.700  0 201 HIS 1 NE2 1 ? 
ATOM   1594 N N   . ASP A 1 200 ? -2.806  25.837  -11.036 0.330 24.390  0 202 ASP 1 N   1 ? 
ATOM   1595 C CA  . ASP A 1 200 ? -2.684  26.915  -10.025 0.330 25.030  0 202 ASP 1 CA  1 ? 
ATOM   1596 C C   . ASP A 1 200 ? -1.745  26.412  -8.919  0.330 27.650  0 202 ASP 1 C   1 ? 
ATOM   1597 O O   . ASP A 1 200 ? -1.211  25.298  -9.053  0.330 26.540  0 202 ASP 1 O   1 ? 
ATOM   1598 C CB  . ASP A 1 200 ? -4.053  27.326  -9.489  0.330 25.990  0 202 ASP 1 CB  1 ? 
ATOM   1599 C CG  . ASP A 1 200 ? -4.593  26.344  -8.477  0.330 25.710  0 202 ASP 1 CG  1 ? 
ATOM   1600 O OD1 . ASP A 1 200 ? -4.135  25.174  -8.511  0.330 23.910  0 202 ASP 1 OD1 1 ? 
ATOM   1601 O OD2 . ASP A 1 200 ? -5.435  26.758  -7.648  0.330 26.860  0 202 ASP 1 OD2 1 ? 
ATOM   1602 N N   . LYS A 1 201 ? -1.556  27.209  -7.863  0.330 28.120  0 203 LYS 1 N   1 ? 
ATOM   1603 C CA  . LYS A 1 201 ? -0.431  27.068  -6.903  0.330 29.850  0 203 LYS 1 CA  1 ? 
ATOM   1604 C C   . LYS A 1 201 ? -0.338  25.625  -6.379  0.330 29.860  0 203 LYS 1 C   1 ? 
ATOM   1605 O O   . LYS A 1 201 ? 0.765   25.015  -6.468  0.330 32.520  0 203 LYS 1 O   1 ? 
ATOM   1606 C CB  . LYS A 1 201 ? -0.609  28.079  -5.769  0.330 30.310  0 203 LYS 1 CB  1 ? 
ATOM   1607 C CG  . LYS A 1 201 ? 0.463   28.032  -4.689  0.330 33.000  0 203 LYS 1 CG  1 ? 
ATOM   1608 C CD  . LYS A 1 201 ? 0.278   29.128  -3.652  0.330 32.890  0 203 LYS 1 CD  1 ? 
ATOM   1609 C CE  . LYS A 1 201 ? 0.725   28.744  -2.259  0.330 33.240  0 203 LYS 1 CE  1 ? 
ATOM   1610 N NZ  . LYS A 1 201 ? 0.252   29.734  -1.259  0.330 30.800  0 203 LYS 1 NZ  1 ? 
ATOM   1611 N N   . ASP A 1 202 ? -1.430  25.088  -5.849  0.330 27.460  0 204 ASP 1 N   1 ? 
ATOM   1612 C CA  . ASP A 1 202 ? -1.419  23.771  -5.153  0.330 28.750  0 204 ASP 1 CA  1 ? 
ATOM   1613 C C   . ASP A 1 202 ? -2.153  22.715  -5.985  0.330 27.450  0 204 ASP 1 C   1 ? 
ATOM   1614 O O   . ASP A 1 202 ? -2.668  21.743  -5.399  0.330 28.410  0 204 ASP 1 O   1 ? 
ATOM   1615 C CB  . ASP A 1 202 ? -2.024  23.898  -3.757  0.330 29.700  0 204 ASP 1 CB  1 ? 
ATOM   1616 C CG  . ASP A 1 202 ? -1.058  24.516  -2.761  0.330 31.560  0 204 ASP 1 CG  1 ? 
ATOM   1617 O OD1 . ASP A 1 202 ? 0.115   24.060  -2.713  0.330 30.850  0 204 ASP 1 OD1 1 ? 
ATOM   1618 O OD2 . ASP A 1 202 ? -1.475  25.451  -2.059  0.330 31.420  0 204 ASP 1 OD2 1 ? 
ATOM   1619 N N   . TYR A 1 203 ? -2.185  22.873  -7.303  0.330 25.650  0 205 TYR 1 N   1 ? 
ATOM   1620 C CA  . TYR A 1 203 ? -2.875  21.920  -8.205  0.330 25.500  0 205 TYR 1 CA  1 ? 
ATOM   1621 C C   . TYR A 1 203 ? -4.272  21.639  -7.640  0.330 26.050  0 205 TYR 1 C   1 ? 
ATOM   1622 O O   . TYR A 1 203 ? -4.599  20.453  -7.367  0.330 25.400  0 205 TYR 1 O   1 ? 
ATOM   1623 C CB  . TYR A 1 203 ? -2.034  20.651  -8.365  0.330 26.300  0 205 TYR 1 CB  1 ? 
ATOM   1624 C CG  . TYR A 1 203 ? -0.720  20.833  -9.080  0.330 26.740  0 205 TYR 1 CG  1 ? 
ATOM   1625 C CD1 . TYR A 1 203 ? 0.372   21.411  -8.454  0.330 28.600  0 205 TYR 1 CD1 1 ? 
ATOM   1626 C CD2 . TYR A 1 203 ? -0.555  20.389  -10.379 0.330 27.730  0 205 TYR 1 CD2 1 ? 
ATOM   1627 C CE1 . TYR A 1 203 ? 1.580   21.575  -9.111  0.330 28.460  0 205 TYR 1 CE1 1 ? 
ATOM   1628 C CE2 . TYR A 1 203 ? 0.646   20.544  -11.050 0.330 28.180  0 205 TYR 1 CE2 1 ? 
ATOM   1629 C CZ  . TYR A 1 203 ? 1.721   21.127  -10.410 0.330 28.480  0 205 TYR 1 CZ  1 ? 
ATOM   1630 O OH  . TYR A 1 203 ? 2.896   21.266  -11.083 0.330 30.260  0 205 TYR 1 OH  1 ? 
ATOM   1631 N N   . ASN A 1 204 ? -5.048  22.707  -7.416  0.330 24.800  0 206 ASN 1 N   1 ? 
ATOM   1632 C CA  . ASN A 1 204 ? -6.509  22.641  -7.140  0.330 26.430  0 206 ASN 1 CA  1 ? 
ATOM   1633 C C   . ASN A 1 204 ? -7.265  22.717  -8.469  0.330 24.380  0 206 ASN 1 C   1 ? 
ATOM   1634 O O   . ASN A 1 204 ? -8.397  22.206  -8.530  0.330 26.130  0 206 ASN 1 O   1 ? 
ATOM   1635 C CB  . ASN A 1 204 ? -6.972  23.742  -6.184  0.330 27.640  0 206 ASN 1 CB  1 ? 
ATOM   1636 C CG  . ASN A 1 204 ? -6.491  23.508  -4.768  0.330 30.630  0 206 ASN 1 CG  1 ? 
ATOM   1637 O OD1 . ASN A 1 204 ? -6.565  22.390  -4.248  0.330 31.210  0 206 ASN 1 OD1 1 ? 
ATOM   1638 N ND2 . ASN A 1 204 ? -5.977  24.560  -4.151  0.330 31.570  0 206 ASN 1 ND2 1 ? 
ATOM   1639 N N   . LYS A 1 205 ? -6.660  23.365  -9.467  0.330 23.730  0 207 LYS 1 N   1 ? 
ATOM   1640 C CA  . LYS A 1 205 ? -7.171  23.466  -10.858 0.330 24.450  0 207 LYS 1 CA  1 ? 
ATOM   1641 C C   . LYS A 1 205 ? -6.050  23.039  -11.807 0.330 23.330  0 207 LYS 1 C   1 ? 
ATOM   1642 O O   . LYS A 1 205 ? -4.923  23.563  -11.694 0.330 23.270  0 207 LYS 1 O   1 ? 
ATOM   1643 C CB  . LYS A 1 205 ? -7.614  24.891  -11.201 0.330 27.470  0 207 LYS 1 CB  1 ? 
ATOM   1644 C CG  . LYS A 1 205 ? -8.937  25.336  -10.594 0.330 29.990  0 207 LYS 1 CG  1 ? 
ATOM   1645 C CD  . LYS A 1 205 ? -9.386  26.697  -11.094 0.330 33.360  0 207 LYS 1 CD  1 ? 
ATOM   1646 C CE  . LYS A 1 205 ? -10.882 26.904  -10.980 0.330 35.970  0 207 LYS 1 CE  1 ? 
ATOM   1647 N NZ  . LYS A 1 205 ? -11.274 27.320  -9.607  0.330 37.750  0 207 LYS 1 NZ  1 ? 
ATOM   1648 N N   . VAL A 1 206 ? -6.351  22.120  -12.714 0.330 22.520  0 208 VAL 1 N   1 ? 
ATOM   1649 C CA  . VAL A 1 206 ? -5.349  21.514  -13.633 0.330 22.280  0 208 VAL 1 CA  1 ? 
ATOM   1650 C C   . VAL A 1 206 ? -6.018  21.329  -14.997 0.330 22.210  0 208 VAL 1 C   1 ? 
ATOM   1651 O O   . VAL A 1 206 ? -7.144  20.782  -15.044 0.330 21.030  0 208 VAL 1 O   1 ? 
ATOM   1652 C CB  . VAL A 1 206 ? -4.817  20.179  -13.076 0.330 23.450  0 208 VAL 1 CB  1 ? 
ATOM   1653 C CG1 . VAL A 1 206 ? -3.928  19.467  -14.079 0.330 23.840  0 208 VAL 1 CG1 1 ? 
ATOM   1654 C CG2 . VAL A 1 206 ? -4.088  20.351  -11.745 0.330 24.070  0 208 VAL 1 CG2 1 ? 
ATOM   1655 N N   . LYS A 1 207 ? -5.329  21.746  -16.061 0.330 20.580  0 209 LYS 1 N   1 ? 
ATOM   1656 C CA  . LYS A 1 207 ? -5.678  21.398  -17.456 0.330 20.900  0 209 LYS 1 CA  1 ? 
ATOM   1657 C C   . LYS A 1 207 ? -4.789  20.222  -17.877 0.330 20.770  0 209 LYS 1 C   1 ? 
ATOM   1658 O O   . LYS A 1 207 ? -3.564  20.316  -17.709 0.330 20.980  0 209 LYS 1 O   1 ? 
ATOM   1659 C CB  . LYS A 1 207 ? -5.512  22.609  -18.382 0.330 20.790  0 209 LYS 1 CB  1 ? 
ATOM   1660 C CG  . LYS A 1 207 ? -5.994  22.384  -19.803 0.330 20.710  0 209 LYS 1 CG  1 ? 
ATOM   1661 C CD  . LYS A 1 207 ? -5.864  23.602  -20.685 0.330 21.430  0 209 LYS 1 CD  1 ? 
ATOM   1662 C CE  . LYS A 1 207 ? -6.757  24.745  -20.256 0.330 20.970  0 209 LYS 1 CE  1 ? 
ATOM   1663 N NZ  . LYS A 1 207 ? -8.187  24.380  -20.385 0.330 21.090  0 209 LYS 1 NZ  1 ? 
ATOM   1664 N N   . LEU A 1 208 ? -5.404  19.145  -18.364 0.330 21.040  0 210 LEU 1 N   1 ? 
ATOM   1665 C CA  . LEU A 1 208 ? -4.732  17.869  -18.697 0.330 22.010  0 210 LEU 1 CA  1 ? 
ATOM   1666 C C   . LEU A 1 208 ? -4.954  17.577  -20.180 0.330 21.990  0 210 LEU 1 C   1 ? 
ATOM   1667 O O   . LEU A 1 208 ? -6.052  17.850  -20.680 0.330 23.830  0 210 LEU 1 O   1 ? 
ATOM   1668 C CB  . LEU A 1 208 ? -5.309  16.762  -17.811 0.330 24.110  0 210 LEU 1 CB  1 ? 
ATOM   1669 C CG  . LEU A 1 208 ? -4.562  15.435  -17.830 0.330 26.040  0 210 LEU 1 CG  1 ? 
ATOM   1670 C CD1 . LEU A 1 208 ? -3.142  15.606  -17.319 0.330 28.010  0 210 LEU 1 CD1 1 ? 
ATOM   1671 C CD2 . LEU A 1 208 ? -5.300  14.394  -16.993 0.330 26.940  0 210 LEU 1 CD2 1 ? 
ATOM   1672 N N   . TYR A 1 209 ? -3.931  17.051  -20.842 0.330 22.180  0 211 TYR 1 N   1 ? 
ATOM   1673 C CA  . TYR A 1 209 ? -3.940  16.707  -22.279 0.330 22.880  0 211 TYR 1 CA  1 ? 
ATOM   1674 C C   . TYR A 1 209 ? -3.320  15.318  -22.443 0.330 21.860  0 211 TYR 1 C   1 ? 
ATOM   1675 O O   . TYR A 1 209 ? -2.361  14.989  -21.737 0.330 20.480  0 211 TYR 1 O   1 ? 
ATOM   1676 C CB  . TYR A 1 209 ? -3.192  17.783  -23.061 0.330 25.270  0 211 TYR 1 CB  1 ? 
ATOM   1677 C CG  . TYR A 1 209 ? -3.029  17.496  -24.527 0.330 26.470  0 211 TYR 1 CG  1 ? 
ATOM   1678 C CD1 . TYR A 1 209 ? -4.021  17.825  -25.432 0.330 29.550  0 211 TYR 1 CD1 1 ? 
ATOM   1679 C CD2 . TYR A 1 209 ? -1.868  16.923  -25.012 0.330 28.640  0 211 TYR 1 CD2 1 ? 
ATOM   1680 C CE1 . TYR A 1 209 ? -3.872  17.574  -26.785 0.330 29.750  0 211 TYR 1 CE1 1 ? 
ATOM   1681 C CE2 . TYR A 1 209 ? -1.697  16.672  -26.363 0.330 30.340  0 211 TYR 1 CE2 1 ? 
ATOM   1682 C CZ  . TYR A 1 209 ? -2.707  16.994  -27.250 0.330 31.420  0 211 TYR 1 CZ  1 ? 
ATOM   1683 O OH  . TYR A 1 209 ? -2.558  16.740  -28.582 0.330 33.190  0 211 TYR 1 OH  1 ? 
ATOM   1684 N N   . GLU A 1 210 ? -3.903  14.505  -23.316 0.330 22.800  0 212 GLU 1 N   1 ? 
ATOM   1685 C CA  . GLU A 1 210 ? -3.347  13.180  -23.673 0.330 22.950  0 212 GLU 1 CA  1 ? 
ATOM   1686 C C   . GLU A 1 210 ? -3.498  13.003  -25.180 0.330 23.590  0 212 GLU 1 C   1 ? 
ATOM   1687 O O   . GLU A 1 210 ? -4.585  13.333  -25.703 0.330 24.050  0 212 GLU 1 O   1 ? 
ATOM   1688 C CB  . GLU A 1 210 ? -4.040  12.036  -22.927 0.330 23.490  0 212 GLU 1 CB  1 ? 
ATOM   1689 C CG  . GLU A 1 210 ? -3.277  10.726  -23.068 0.330 24.490  0 212 GLU 1 CG  1 ? 
ATOM   1690 C CD  . GLU A 1 210 ? -4.038  9.405   -23.062 0.330 24.150  0 212 GLU 1 CD  1 ? 
ATOM   1691 O OE1 . GLU A 1 210 ? -5.267  9.386   -22.852 0.330 24.420  0 212 GLU 1 OE1 1 ? 
ATOM   1692 O OE2 . GLU A 1 210 ? -3.377  8.390   -23.286 0.330 23.690  0 212 GLU 1 OE2 1 ? 
ATOM   1693 N N   . HIS A 1 211 ? -2.438  12.512  -25.829 0.330 26.000  0 213 HIS 1 N   1 ? 
ATOM   1694 C CA  . HIS A 1 211 ? -2.422  12.042  -27.242 0.330 26.070  0 213 HIS 1 CA  1 ? 
ATOM   1695 C C   . HIS A 1 211 ? -1.990  10.572  -27.262 0.330 25.050  0 213 HIS 1 C   1 ? 
ATOM   1696 O O   . HIS A 1 211 ? -0.944  10.266  -26.657 0.330 24.850  0 213 HIS 1 O   1 ? 
ATOM   1697 C CB  . HIS A 1 211 ? -1.484  12.887  -28.104 0.330 26.750  0 213 HIS 1 CB  1 ? 
ATOM   1698 C CG  . HIS A 1 211 ? -1.424  12.424  -29.522 0.330 29.400  0 213 HIS 1 CG  1 ? 
ATOM   1699 N ND1 . HIS A 1 211 ? -0.280  11.872  -30.082 0.330 30.850  0 213 HIS 1 ND1 1 ? 
ATOM   1700 C CD2 . HIS A 1 211 ? -2.363  12.428  -30.498 0.330 31.160  0 213 HIS 1 CD2 1 ? 
ATOM   1701 C CE1 . HIS A 1 211 ? -0.515  11.571  -31.347 0.330 31.180  0 213 HIS 1 CE1 1 ? 
ATOM   1702 N NE2 . HIS A 1 211 ? -1.791  11.891  -31.622 0.330 30.110  0 213 HIS 1 NE2 1 ? 
ATOM   1703 N N   . ALA A 1 212 ? -2.769  9.711   -27.922 0.330 24.560  0 214 ALA 1 N   1 ? 
ATOM   1704 C CA  . ALA A 1 212 ? -2.545  8.250   -27.959 0.330 24.180  0 214 ALA 1 CA  1 ? 
ATOM   1705 C C   . ALA A 1 212 ? -2.754  7.727   -29.378 0.330 24.420  0 214 ALA 1 C   1 ? 
ATOM   1706 O O   . ALA A 1 212 ? -3.742  8.126   -30.025 0.330 25.600  0 214 ALA 1 O   1 ? 
ATOM   1707 C CB  . ALA A 1 212 ? -3.458  7.558   -26.988 0.330 24.720  0 214 ALA 1 CB  1 ? 
ATOM   1708 N N   . VAL A 1 213 ? -1.869  6.833   -29.815 0.330 24.840  0 215 VAL 1 N   1 ? 
ATOM   1709 C CA  . VAL A 1 213 ? -1.882  6.230   -31.181 0.330 25.460  0 215 VAL 1 CA  1 ? 
ATOM   1710 C C   . VAL A 1 213 ? -1.601  4.728   -31.077 0.330 25.040  0 215 VAL 1 C   1 ? 
ATOM   1711 O O   . VAL A 1 213 ? -0.570  4.351   -30.474 0.330 24.800  0 215 VAL 1 O   1 ? 
ATOM   1712 C CB  . VAL A 1 213 ? -0.858  6.922   -32.098 0.330 26.410  0 215 VAL 1 CB  1 ? 
ATOM   1713 C CG1 . VAL A 1 213 ? -0.853  6.309   -33.485 0.330 28.430  0 215 VAL 1 CG1 1 ? 
ATOM   1714 C CG2 . VAL A 1 213 ? -1.101  8.415   -32.185 0.330 27.370  0 215 VAL 1 CG2 1 ? 
ATOM   1715 N N   . ALA A 1 214 ? -2.472  3.910   -31.675 0.330 24.670  0 216 ALA 1 N   1 ? 
ATOM   1716 C CA  . ALA A 1 214 ? -2.326  2.438   -31.749 0.330 25.990  0 216 ALA 1 CA  1 ? 
ATOM   1717 C C   . ALA A 1 214 ? -1.506  2.076   -32.995 0.330 26.780  0 216 ALA 1 C   1 ? 
ATOM   1718 O O   . ALA A 1 214 ? -1.723  2.707   -34.050 0.330 26.270  0 216 ALA 1 O   1 ? 
ATOM   1719 C CB  . ALA A 1 214 ? -3.682  1.792   -31.751 0.330 26.180  0 216 ALA 1 CB  1 ? 
ATOM   1720 N N   . HIS A 1 215 ? -0.574  1.128   -32.863 0.330 28.470  0 217 HIS 1 N   1 ? 
ATOM   1721 C CA  . HIS A 1 215 ? 0.312   0.648   -33.960 0.330 29.450  0 217 HIS 1 CA  1 ? 
ATOM   1722 C C   . HIS A 1 215 ? 0.732   -0.803  -33.703 0.330 31.650  0 217 HIS 1 C   1 ? 
ATOM   1723 O O   . HIS A 1 215 ? 0.545   -1.284  -32.571 0.330 29.110  0 217 HIS 1 O   1 ? 
ATOM   1724 C CB  . HIS A 1 215 ? 1.526   1.574   -34.119 0.330 29.130  0 217 HIS 1 CB  1 ? 
ATOM   1725 C CG  . HIS A 1 215 ? 2.405   1.624   -32.915 0.330 29.300  0 217 HIS 1 CG  1 ? 
ATOM   1726 N ND1 . HIS A 1 215 ? 3.399   0.697   -32.690 0.330 30.030  0 217 HIS 1 ND1 1 ? 
ATOM   1727 C CD2 . HIS A 1 215 ? 2.414   2.458   -31.855 0.330 29.160  0 217 HIS 1 CD2 1 ? 
ATOM   1728 C CE1 . HIS A 1 215 ? 4.000   0.966   -31.549 0.330 30.400  0 217 HIS 1 CE1 1 ? 
ATOM   1729 N NE2 . HIS A 1 215 ? 3.417   2.048   -31.020 0.330 31.080  0 217 HIS 1 NE2 1 ? 
ATOM   1730 N N   . SER A 1 216 ? 1.288   -1.464  -34.726 0.330 34.160  0 218 SER 1 N   1 ? 
ATOM   1731 C CA  . SER A 1 216 ? 1.688   -2.897  -34.713 0.330 37.960  0 218 SER 1 CA  1 ? 
ATOM   1732 C C   . SER A 1 216 ? 3.160   -3.033  -34.303 0.330 41.850  0 218 SER 1 C   1 ? 
ATOM   1733 O O   . SER A 1 216 ? 3.609   -4.176  -34.092 0.330 41.920  0 218 SER 1 O   1 ? 
ATOM   1734 C CB  . SER A 1 216 ? 1.456   -3.541  -36.061 0.330 37.690  0 218 SER 1 CB  1 ? 
ATOM   1735 O OG  . SER A 1 216 ? 0.401   -2.902  -36.778 0.330 35.310  0 218 SER 1 OG  1 ? 
ATOM   1736 N N   . GLY A 1 217 ? 3.880   -1.910  -34.213 0.330 45.670  0 219 GLY 1 N   1 ? 
ATOM   1737 C CA  . GLY A 1 217 ? 5.293   -1.855  -33.792 0.330 52.260  0 219 GLY 1 CA  1 ? 
ATOM   1738 C C   . GLY A 1 217 ? 6.177   -1.246  -34.866 0.330 58.360  0 219 GLY 1 C   1 ? 
ATOM   1739 O O   . GLY A 1 217 ? 7.256   -0.737  -34.517 0.330 60.500  0 219 GLY 1 O   1 ? 
ATOM   1740 N N   . LEU A 1 218 ? 5.726   -1.300  -36.124 0.330 67.430  0 220 LEU 1 N   1 ? 
ATOM   1741 C CA  . LEU A 1 218 ? 6.447   -0.775  -37.316 0.330 74.620  0 220 LEU 1 CA  1 ? 
ATOM   1742 C C   . LEU A 1 218 ? 6.226   0.734   -37.420 0.330 82.840  0 220 LEU 1 C   1 ? 
ATOM   1743 O O   . LEU A 1 218 ? 5.349   1.293   -36.761 0.330 82.770  0 220 LEU 1 O   1 ? 
ATOM   1744 C CB  . LEU A 1 218 ? 5.946   -1.521  -38.559 0.330 75.360  0 220 LEU 1 CB  1 ? 
ATOM   1745 C CG  . LEU A 1 218 ? 6.208   -3.028  -38.557 0.330 75.420  0 220 LEU 1 CG  1 ? 
ATOM   1746 C CD1 . LEU A 1 218 ? 5.454   -3.726  -39.681 0.330 73.870  0 220 LEU 1 CD1 1 ? 
ATOM   1747 C CD2 . LEU A 1 218 ? 7.701   -3.319  -38.646 0.330 74.690  0 220 LEU 1 CD2 1 ? 
ATOM   1748 N N   . PRO A 1 219 ? 7.024   1.445   -38.249 0.330 92.470  0 221 PRO 1 N   1 ? 
ATOM   1749 C CA  . PRO A 1 219 ? 6.981   2.908   -38.295 0.330 94.970  0 221 PRO 1 CA  1 ? 
ATOM   1750 C C   . PRO A 1 219 ? 5.673   3.441   -38.905 0.330 97.060  0 221 PRO 1 C   1 ? 
ATOM   1751 O O   . PRO A 1 219 ? 5.596   3.846   -40.069 0.330 99.260  0 221 PRO 1 O   1 ? 
ATOM   1752 C CB  . PRO A 1 219 ? 8.205   3.273   -39.154 0.330 96.450  0 221 PRO 1 CB  1 ? 
ATOM   1753 C CG  . PRO A 1 219 ? 8.437   2.054   -40.031 0.330 96.250  0 221 PRO 1 CG  1 ? 
ATOM   1754 C CD  . PRO A 1 219 ? 7.997   0.870   -39.193 0.330 95.150  0 221 PRO 1 CD  1 ? 
ATOM   1755 N N   . SER B 1 2   ? -21.720 5.867   -37.029 0.670 89.940  0 2   SER 2 N   1 ? 
ATOM   1756 C CA  . SER B 1 2   ? -21.181 5.346   -35.740 0.670 85.300  0 2   SER 2 CA  1 ? 
ATOM   1757 C C   . SER B 1 2   ? -21.885 6.045   -34.561 0.670 74.780  0 2   SER 2 C   1 ? 
ATOM   1758 O O   . SER B 1 2   ? -22.337 7.197   -34.740 0.670 71.960  0 2   SER 2 O   1 ? 
ATOM   1759 C CB  . SER B 1 2   ? -19.674 5.534   -35.679 0.670 88.720  0 2   SER 2 CB  1 ? 
ATOM   1760 O OG  . SER B 1 2   ? -19.138 5.071   -34.445 0.670 88.490  0 2   SER 2 OG  1 ? 
ATOM   1761 N N   . ALA B 1 3   ? -21.970 5.374   -33.405 0.670 64.350  0 3   ALA 2 N   1 ? 
ATOM   1762 C CA  . ALA B 1 3   ? -22.454 5.941   -32.120 0.670 58.030  0 3   ALA 2 CA  1 ? 
ATOM   1763 C C   . ALA B 1 3   ? -21.555 7.119   -31.709 0.670 52.100  0 3   ALA 2 C   1 ? 
ATOM   1764 O O   . ALA B 1 3   ? -22.079 8.105   -31.150 0.670 57.760  0 3   ALA 2 O   1 ? 
ATOM   1765 C CB  . ALA B 1 3   ? -22.470 4.865   -31.062 0.670 57.590  0 3   ALA 2 CB  1 ? 
ATOM   1766 N N   . ILE B 1 4   ? -20.264 7.037   -32.048 0.670 42.510  0 4   ILE 2 N   1 ? 
ATOM   1767 C CA  . ILE B 1 4   ? -19.176 7.960   -31.618 0.670 37.910  0 4   ILE 2 CA  1 ? 
ATOM   1768 C C   . ILE B 1 4   ? -18.967 9.072   -32.654 0.670 34.970  0 4   ILE 2 C   1 ? 
ATOM   1769 O O   . ILE B 1 4   ? -18.616 8.777   -33.795 0.670 35.070  0 4   ILE 2 O   1 ? 
ATOM   1770 C CB  . ILE B 1 4   ? -17.905 7.132   -31.365 0.670 34.510  0 4   ILE 2 CB  1 ? 
ATOM   1771 C CG1 . ILE B 1 4   ? -18.045 6.346   -30.055 0.670 36.200  0 4   ILE 2 CG1 1 ? 
ATOM   1772 C CG2 . ILE B 1 4   ? -16.664 8.002   -31.388 0.670 35.020  0 4   ILE 2 CG2 1 ? 
ATOM   1773 C CD1 . ILE B 1 4   ? -17.141 5.180   -29.965 0.670 34.870  0 4   ILE 2 CD1 1 ? 
ATOM   1774 N N   . LYS B 1 5   ? -19.133 10.327  -32.239 0.670 33.720  0 5   LYS 2 N   1 ? 
ATOM   1775 C CA  . LYS B 1 5   ? -19.010 11.509  -33.122 0.670 34.980  0 5   LYS 2 CA  1 ? 
ATOM   1776 C C   . LYS B 1 5   ? -17.550 11.948  -33.127 0.670 30.220  0 5   LYS 2 C   1 ? 
ATOM   1777 O O   . LYS B 1 5   ? -16.806 11.572  -32.230 0.670 27.000  0 5   LYS 2 O   1 ? 
ATOM   1778 C CB  . LYS B 1 5   ? -19.907 12.639  -32.615 0.670 39.840  0 5   LYS 2 CB  1 ? 
ATOM   1779 C CG  . LYS B 1 5   ? -21.361 12.258  -32.360 0.670 47.890  0 5   LYS 2 CG  1 ? 
ATOM   1780 C CD  . LYS B 1 5   ? -22.024 11.618  -33.549 0.670 55.520  0 5   LYS 2 CD  1 ? 
ATOM   1781 C CE  . LYS B 1 5   ? -23.541 11.614  -33.487 0.670 58.070  0 5   LYS 2 CE  1 ? 
ATOM   1782 N NZ  . LYS B 1 5   ? -24.119 10.907  -34.658 0.670 57.780  0 5   LYS 2 NZ  1 ? 
ATOM   1783 N N   . PRO B 1 6   ? -17.117 12.785  -34.093 0.670 28.880  0 6   PRO 2 N   1 ? 
ATOM   1784 C CA  . PRO B 1 6   ? -15.740 13.285  -34.142 0.670 27.220  0 6   PRO 2 CA  1 ? 
ATOM   1785 C C   . PRO B 1 6   ? -15.357 14.221  -32.986 0.670 25.940  0 6   PRO 2 C   1 ? 
ATOM   1786 O O   . PRO B 1 6   ? -14.187 14.337  -32.714 0.670 24.710  0 6   PRO 2 O   1 ? 
ATOM   1787 C CB  . PRO B 1 6   ? -15.654 14.101  -35.435 0.670 29.170  0 6   PRO 2 CB  1 ? 
ATOM   1788 C CG  . PRO B 1 6   ? -16.858 13.674  -36.234 0.670 30.170  0 6   PRO 2 CG  1 ? 
ATOM   1789 C CD  . PRO B 1 6   ? -17.914 13.258  -35.237 0.670 30.420  0 6   PRO 2 CD  1 ? 
ATOM   1790 N N   . ASP B 1 7   ? -16.355 14.877  -32.385 0.670 26.200  0 7   ASP 2 N   1 ? 
ATOM   1791 C CA  . ASP B 1 7   ? -16.227 15.784  -31.214 0.670 26.380  0 7   ASP 2 CA  1 ? 
ATOM   1792 C C   . ASP B 1 7   ? -17.120 15.256  -30.105 0.670 25.860  0 7   ASP 2 C   1 ? 
ATOM   1793 O O   . ASP B 1 7   ? -18.298 15.094  -30.349 0.670 24.250  0 7   ASP 2 O   1 ? 
ATOM   1794 C CB  . ASP B 1 7   ? -16.636 17.213  -31.563 0.670 29.030  0 7   ASP 2 CB  1 ? 
ATOM   1795 C CG  . ASP B 1 7   ? -15.561 17.897  -32.374 0.670 32.170  0 7   ASP 2 CG  1 ? 
ATOM   1796 O OD1 . ASP B 1 7   ? -14.447 18.029  -31.842 0.670 31.670  0 7   ASP 2 OD1 1 ? 
ATOM   1797 O OD2 . ASP B 1 7   ? -15.828 18.231  -33.541 0.670 36.630  0 7   ASP 2 OD2 1 ? 
ATOM   1798 N N   . MET B 1 8   ? -16.551 14.960  -28.943 0.670 23.270  0 8   MET 2 N   1 ? 
ATOM   1799 C CA  . MET B 1 8   ? -17.294 14.370  -27.823 0.670 23.190  0 8   MET 2 CA  1 ? 
ATOM   1800 C C   . MET B 1 8   ? -16.913 15.133  -26.564 0.670 22.480  0 8   MET 2 C   1 ? 
ATOM   1801 O O   . MET B 1 8   ? -15.803 15.665  -26.511 0.670 24.050  0 8   MET 2 O   1 ? 
ATOM   1802 C CB  . MET B 1 8   ? -16.969 12.884  -27.671 0.670 25.490  0 8   MET 2 CB  1 ? 
ATOM   1803 C CG  . MET B 1 8   ? -17.484 12.032  -28.826 0.670 28.420  0 8   MET 2 CG  1 ? 
ATOM   1804 S SD  . MET B 1 8   ? -19.293 11.853  -28.818 0.670 30.160  0 8   MET 2 SD  1 ? 
ATOM   1805 C CE  . MET B 1 8   ? -19.568 10.719  -27.453 0.670 26.720  0 8   MET 2 CE  1 ? 
ATOM   1806 N N   . LYS B 1 9   ? -17.819 15.172  -25.603 0.670 23.200  0 9   LYS 2 N   1 ? 
ATOM   1807 C CA  . LYS B 1 9   ? -17.590 15.848  -24.308 0.670 22.400  0 9   LYS 2 CA  1 ? 
ATOM   1808 C C   . LYS B 1 9   ? -17.246 14.786  -23.282 0.670 20.590  0 9   LYS 2 C   1 ? 
ATOM   1809 O O   . LYS B 1 9   ? -17.612 13.618  -23.482 0.670 17.860  0 9   LYS 2 O   1 ? 
ATOM   1810 C CB  . LYS B 1 9   ? -18.821 16.645  -23.893 0.670 26.930  0 9   LYS 2 CB  1 ? 
ATOM   1811 C CG  . LYS B 1 9   ? -19.224 17.704  -24.895 0.670 30.680  0 9   LYS 2 CG  1 ? 
ATOM   1812 C CD  . LYS B 1 9   ? -20.406 18.495  -24.426 0.670 38.150  0 9   LYS 2 CD  1 ? 
ATOM   1813 C CE  . LYS B 1 9   ? -21.139 19.180  -25.562 0.670 43.730  0 9   LYS 2 CE  1 ? 
ATOM   1814 N NZ  . LYS B 1 9   ? -22.603 19.130  -25.344 0.670 47.150  0 9   LYS 2 NZ  1 ? 
ATOM   1815 N N   . ILE B 1 10  ? -16.592 15.211  -22.212 0.670 19.670  0 10  ILE 2 N   1 ? 
ATOM   1816 C CA  . ILE B 1 10  ? -16.152 14.326  -21.107 0.670 19.320  0 10  ILE 2 CA  1 ? 
ATOM   1817 C C   . ILE B 1 10  ? -16.666 14.958  -19.817 0.670 19.340  0 10  ILE 2 C   1 ? 
ATOM   1818 O O   . ILE B 1 10  ? -16.378 16.153  -19.605 0.670 18.690  0 10  ILE 2 O   1 ? 
ATOM   1819 C CB  . ILE B 1 10  ? -14.613 14.191  -21.108 0.670 19.510  0 10  ILE 2 CB  1 ? 
ATOM   1820 C CG1 . ILE B 1 10  ? -14.046 13.671  -22.431 0.670 20.860  0 10  ILE 2 CG1 1 ? 
ATOM   1821 C CG2 . ILE B 1 10  ? -14.162 13.300  -19.965 0.670 19.610  0 10  ILE 2 CG2 1 ? 
ATOM   1822 C CD1 . ILE B 1 10  ? -12.547 14.016  -22.605 0.670 21.820  0 10  ILE 2 CD1 1 ? 
ATOM   1823 N N   . LYS B 1 11  ? -17.345 14.161  -18.983 0.670 19.110  0 11  LYS 2 N   1 ? 
ATOM   1824 C CA  . LYS B 1 11  ? -17.716 14.520  -17.592 0.670 20.470  0 11  LYS 2 CA  1 ? 
ATOM   1825 C C   . LYS B 1 11  ? -17.173 13.434  -16.685 0.670 19.750  0 11  LYS 2 C   1 ? 
ATOM   1826 O O   . LYS B 1 11  ? -17.302 12.269  -17.029 0.670 17.690  0 11  LYS 2 O   1 ? 
ATOM   1827 C CB  . LYS B 1 11  ? -19.227 14.597  -17.379 0.670 21.950  0 11  LYS 2 CB  1 ? 
ATOM   1828 C CG  . LYS B 1 11  ? -19.947 15.627  -18.229 0.670 25.290  0 11  LYS 2 CG  1 ? 
ATOM   1829 C CD  . LYS B 1 11  ? -19.766 17.012  -17.776 0.670 30.810  0 11  LYS 2 CD  1 ? 
ATOM   1830 C CE  . LYS B 1 11  ? -20.519 17.965  -18.683 0.670 37.710  0 11  LYS 2 CE  1 ? 
ATOM   1831 N NZ  . LYS B 1 11  ? -20.048 19.355  -18.505 0.670 45.550  0 11  LYS 2 NZ  1 ? 
ATOM   1832 N N   . LEU B 1 12  ? -16.623 13.823  -15.539 0.670 20.570  0 12  LEU 2 N   1 ? 
ATOM   1833 C CA  . LEU B 1 12  ? -15.913 12.867  -14.683 0.670 20.660  0 12  LEU 2 CA  1 ? 
ATOM   1834 C C   . LEU B 1 12  ? -16.061 13.274  -13.216 0.670 18.370  0 12  LEU 2 C   1 ? 
ATOM   1835 O O   . LEU B 1 12  ? -16.086 14.472  -12.910 0.670 17.020  0 12  LEU 2 O   1 ? 
ATOM   1836 C CB  . LEU B 1 12  ? -14.460 12.863  -15.151 0.670 24.470  0 12  LEU 2 CB  1 ? 
ATOM   1837 C CG  . LEU B 1 12  ? -13.546 11.905  -14.408 0.670 31.100  0 12  LEU 2 CG  1 ? 
ATOM   1838 C CD1 . LEU B 1 12  ? -12.538 11.278  -15.378 0.670 36.590  0 12  LEU 2 CD1 1 ? 
ATOM   1839 C CD2 . LEU B 1 12  ? -12.847 12.639  -13.256 0.670 29.920  0 12  LEU 2 CD2 1 ? 
ATOM   1840 N N   . ARG B 1 13  ? -16.112 12.278  -12.348 0.670 17.930  0 13  ARG 2 N   1 ? 
ATOM   1841 C CA  . ARG B 1 13  ? -15.984 12.467  -10.892 0.670 20.430  0 13  ARG 2 CA  1 ? 
ATOM   1842 C C   . ARG B 1 13  ? -15.085 11.354  -10.392 0.670 19.040  0 13  ARG 2 C   1 ? 
ATOM   1843 O O   . ARG B 1 13  ? -15.299 10.178  -10.769 0.670 17.990  0 13  ARG 2 O   1 ? 
ATOM   1844 C CB  . ARG B 1 13  ? -17.335 12.477  -10.163 0.670 23.940  0 13  ARG 2 CB  1 ? 
ATOM   1845 C CG  . ARG B 1 13  ? -17.159 12.447  -8.651  0.670 28.600  0 13  ARG 2 CG  1 ? 
ATOM   1846 C CD  . ARG B 1 13  ? -18.363 12.860  -7.844  0.670 36.770  0 13  ARG 2 CD  1 ? 
ATOM   1847 N NE  . ARG B 1 13  ? -18.556 14.297  -7.951  0.670 44.390  0 13  ARG 2 NE  1 ? 
ATOM   1848 C CZ  . ARG B 1 13  ? -19.068 15.073  -7.005  0.670 46.790  0 13  ARG 2 CZ  1 ? 
ATOM   1849 N NH1 . ARG B 1 13  ? -19.199 16.367  -7.239  0.670 47.170  0 13  ARG 2 NH1 1 ? 
ATOM   1850 N NH2 . ARG B 1 13  ? -19.416 14.567  -5.830  0.670 48.800  0 13  ARG 2 NH2 1 ? 
ATOM   1851 N N   . MET B 1 14  ? -14.055 11.738  -9.669  0.670 18.550  0 14  MET 2 N   1 ? 
ATOM   1852 C CA  . MET B 1 14  ? -13.092 10.819  -9.023  0.670 18.730  0 14  MET 2 CA  1 ? 
ATOM   1853 C C   . MET B 1 14  ? -13.298 10.992  -7.521  0.670 20.710  0 14  MET 2 C   1 ? 
ATOM   1854 O O   . MET B 1 14  ? -13.353 12.167  -7.048  0.670 18.950  0 14  MET 2 O   1 ? 
ATOM   1855 C CB  . MET B 1 14  ? -11.636 11.134  -9.393  0.670 19.520  0 14  MET 2 CB  1 ? 
ATOM   1856 C CG  . MET B 1 14  ? -10.624 10.294  -8.620  0.670 19.030  0 14  MET 2 CG  1 ? 
ATOM   1857 S SD  . MET B 1 14  ? -8.916  10.753  -8.897  0.670 21.700  0 14  MET 2 SD  1 ? 
ATOM   1858 C CE  . MET B 1 14  ? -8.530  9.898   -10.421 0.670 21.820  0 14  MET 2 CE  1 ? 
ATOM   1859 N N   . GLU B 1 15  ? -13.505 9.878   -6.822  0.670 20.850  0 15  GLU 2 N   1 ? 
ATOM   1860 C CA  . GLU B 1 15  ? -13.357 9.842   -5.346  0.670 23.050  0 15  GLU 2 CA  1 ? 
ATOM   1861 C C   . GLU B 1 15  ? -12.157 8.957   -5.048  0.670 20.630  0 15  GLU 2 C   1 ? 
ATOM   1862 O O   . GLU B 1 15  ? -11.916 7.986   -5.816  0.670 20.300  0 15  GLU 2 O   1 ? 
ATOM   1863 C CB  . GLU B 1 15  ? -14.613 9.310   -4.667  0.670 26.640  0 15  GLU 2 CB  1 ? 
ATOM   1864 C CG  . GLU B 1 15  ? -15.837 10.153  -4.935  0.670 33.600  0 15  GLU 2 CG  1 ? 
ATOM   1865 C CD  . GLU B 1 15  ? -17.075 9.741   -4.153  0.670 39.550  0 15  GLU 2 CD  1 ? 
ATOM   1866 O OE1 . GLU B 1 15  ? -18.178 9.795   -4.754  0.670 44.440  0 15  GLU 2 OE1 1 ? 
ATOM   1867 O OE2 . GLU B 1 15  ? -16.924 9.353   -2.955  0.670 42.350  0 15  GLU 2 OE2 1 ? 
ATOM   1868 N N   . GLY B 1 16  ? -11.427 9.254   -3.990  0.670 17.160  0 16  GLY 2 N   1 ? 
ATOM   1869 C CA  . GLY B 1 16  ? -10.292 8.386   -3.645  0.670 19.630  0 16  GLY 2 CA  1 ? 
ATOM   1870 C C   . GLY B 1 16  ? -9.600  8.702   -2.351  0.670 17.410  0 16  GLY 2 C   1 ? 
ATOM   1871 O O   . GLY B 1 16  ? -9.999  9.604   -1.597  0.670 15.520  0 16  GLY 2 O   1 ? 
ATOM   1872 N N   . ASN B 1 17  ? -8.555  7.948   -2.120  0.670 18.470  0 17  ASN 2 N   1 ? 
ATOM   1873 C CA  . ASN B 1 17  ? -7.824  7.984   -0.846  0.670 20.720  0 17  ASN 2 CA  1 ? 
ATOM   1874 C C   . ASN B 1 17  ? -6.380  7.632   -1.185  0.670 19.700  0 17  ASN 2 C   1 ? 
ATOM   1875 O O   . ASN B 1 17  ? -6.173  6.556   -1.766  0.670 20.130  0 17  ASN 2 O   1 ? 
ATOM   1876 C CB  . ASN B 1 17  ? -8.561  7.047   0.114   0.670 23.030  0 17  ASN 2 CB  1 ? 
ATOM   1877 C CG  . ASN B 1 17  ? -8.001  7.149   1.506   0.670 28.200  0 17  ASN 2 CG  1 ? 
ATOM   1878 O OD1 . ASN B 1 17  ? -6.838  6.806   1.727   0.670 32.370  0 17  ASN 2 OD1 1 ? 
ATOM   1879 N ND2 . ASN B 1 17  ? -8.805  7.677   2.412   0.670 32.710  0 17  ASN 2 ND2 1 ? 
ATOM   1880 N N   . VAL B 1 18  ? -5.424  8.487   -0.833  0.670 19.270  0 18  VAL 2 N   1 ? 
ATOM   1881 C CA  . VAL B 1 18  ? -3.975  8.169   -0.954  0.670 19.010  0 18  VAL 2 CA  1 ? 
ATOM   1882 C C   . VAL B 1 18  ? -3.337  8.339   0.424   0.670 19.080  0 18  VAL 2 C   1 ? 
ATOM   1883 O O   . VAL B 1 18  ? -3.411  9.444   0.981   0.670 18.890  0 18  VAL 2 O   1 ? 
ATOM   1884 C CB  . VAL B 1 18  ? -3.300  9.023   -2.038  0.670 20.520  0 18  VAL 2 CB  1 ? 
ATOM   1885 C CG1 . VAL B 1 18  ? -1.783  8.885   -2.038  0.670 22.710  0 18  VAL 2 CG1 1 ? 
ATOM   1886 C CG2 . VAL B 1 18  ? -3.865  8.690   -3.400  0.670 20.700  0 18  VAL 2 CG2 1 ? 
ATOM   1887 N N   . ASN B 1 19  ? -2.804  7.242   0.976   0.670 18.940  0 19  ASN 2 N   1 ? 
ATOM   1888 C CA  . ASN B 1 19  ? -2.119  7.226   2.287   0.670 19.870  0 19  ASN 2 CA  1 ? 
ATOM   1889 C C   . ASN B 1 19  ? -3.088  7.724   3.366   0.670 19.840  0 19  ASN 2 C   1 ? 
ATOM   1890 O O   . ASN B 1 19  ? -2.620  8.356   4.300   0.670 18.860  0 19  ASN 2 O   1 ? 
ATOM   1891 C CB  . ASN B 1 19  ? -0.823  8.032   2.213   0.670 20.810  0 19  ASN 2 CB  1 ? 
ATOM   1892 C CG  . ASN B 1 19  ? 0.389   7.189   1.870   0.670 21.690  0 19  ASN 2 CG  1 ? 
ATOM   1893 O OD1 . ASN B 1 19  ? 0.294   6.176   1.164   0.670 19.350  0 19  ASN 2 OD1 1 ? 
ATOM   1894 N ND2 . ASN B 1 19  ? 1.536   7.600   2.386   0.670 20.140  0 19  ASN 2 ND2 1 ? 
ATOM   1895 N N   . GLY B 1 20  ? -4.395  7.471   3.228   0.670 18.600  0 20  GLY 2 N   1 ? 
ATOM   1896 C CA  . GLY B 1 20  ? -5.400  7.937   4.206   0.670 20.500  0 20  GLY 2 CA  1 ? 
ATOM   1897 C C   . GLY B 1 20  ? -5.968  9.328   3.923   0.670 21.240  0 20  GLY 2 C   1 ? 
ATOM   1898 O O   . GLY B 1 20  ? -6.872  9.734   4.674   0.670 24.120  0 20  GLY 2 O   1 ? 
ATOM   1899 N N   . HIS B 1 21  ? -5.495  10.047  2.895   0.670 21.670  0 21  HIS 2 N   1 ? 
ATOM   1900 C CA  . HIS B 1 21  ? -5.992  11.400  2.548   0.670 22.430  0 21  HIS 2 CA  1 ? 
ATOM   1901 C C   . HIS B 1 21  ? -7.143  11.279  1.544   0.670 21.110  0 21  HIS 2 C   1 ? 
ATOM   1902 O O   . HIS B 1 21  ? -6.886  10.854  0.400   0.670 21.740  0 21  HIS 2 O   1 ? 
ATOM   1903 C CB  . HIS B 1 21  ? -4.832  12.263  2.042   0.670 26.580  0 21  HIS 2 CB  1 ? 
ATOM   1904 C CG  . HIS B 1 21  ? -3.681  12.406  2.985   0.670 31.550  0 21  HIS 2 CG  1 ? 
ATOM   1905 N ND1 . HIS B 1 21  ? -3.707  13.302  4.049   0.670 35.350  0 21  HIS 2 ND1 1 ? 
ATOM   1906 C CD2 . HIS B 1 21  ? -2.449  11.836  3.001   0.670 35.820  0 21  HIS 2 CD2 1 ? 
ATOM   1907 C CE1 . HIS B 1 21  ? -2.544  13.262  4.677   0.670 39.010  0 21  HIS 2 CE1 1 ? 
ATOM   1908 N NE2 . HIS B 1 21  ? -1.757  12.357  4.061   0.670 37.270  0 21  HIS 2 NE2 1 ? 
ATOM   1909 N N   . HIS B 1 22  ? -8.354  11.679  1.925   0.670 20.580  0 22  HIS 2 N   1 ? 
ATOM   1910 C CA  . HIS B 1 22  ? -9.599  11.569  1.115   0.670 21.830  0 22  HIS 2 CA  1 ? 
ATOM   1911 C C   . HIS B 1 22  ? -9.705  12.776  0.179   0.670 21.040  0 22  HIS 2 C   1 ? 
ATOM   1912 O O   . HIS B 1 22  ? -9.336  13.909  0.585   0.670 18.230  0 22  HIS 2 O   1 ? 
ATOM   1913 C CB  . HIS B 1 22  ? -10.848 11.470  2.029   0.670 27.410  0 22  HIS 2 CB  1 ? 
ATOM   1914 C CG  . HIS B 1 22  ? -12.155 11.564  1.306   0.670 30.820  0 22  HIS 2 CG  1 ? 
ATOM   1915 N ND1 . HIS B 1 22  ? -12.654 10.520  0.513   0.670 36.580  0 22  HIS 2 ND1 1 ? 
ATOM   1916 C CD2 . HIS B 1 22  ? -13.072 12.558  1.243   0.670 35.840  0 22  HIS 2 CD2 1 ? 
ATOM   1917 C CE1 . HIS B 1 22  ? -13.806 10.891  -0.023  0.670 35.990  0 22  HIS 2 CE1 1 ? 
ATOM   1918 N NE2 . HIS B 1 22  ? -14.100 12.126  0.439   0.670 36.060  0 22  HIS 2 NE2 1 ? 
ATOM   1919 N N   . PHE B 1 23  ? -10.213 12.556  -1.026  0.670 17.890  0 23  PHE 2 N   1 ? 
ATOM   1920 C CA  . PHE B 1 23  ? -10.434 13.672  -1.975  0.670 18.700  0 23  PHE 2 CA  1 ? 
ATOM   1921 C C   . PHE B 1 23  ? -11.519 13.332  -2.979  0.670 17.450  0 23  PHE 2 C   1 ? 
ATOM   1922 O O   . PHE B 1 23  ? -11.817 12.114  -3.229  0.670 16.750  0 23  PHE 2 O   1 ? 
ATOM   1923 C CB  . PHE B 1 23  ? -9.130  14.053  -2.671  0.670 18.850  0 23  PHE 2 CB  1 ? 
ATOM   1924 C CG  . PHE B 1 23  ? -8.511  12.888  -3.387  0.670 19.740  0 23  PHE 2 CG  1 ? 
ATOM   1925 C CD1 . PHE B 1 23  ? -7.643  12.040  -2.732  0.670 19.320  0 23  PHE 2 CD1 1 ? 
ATOM   1926 C CD2 . PHE B 1 23  ? -8.860  12.612  -4.702  0.670 21.730  0 23  PHE 2 CD2 1 ? 
ATOM   1927 C CE1 . PHE B 1 23  ? -7.094  10.944  -3.379  0.670 21.070  0 23  PHE 2 CE1 1 ? 
ATOM   1928 C CE2 . PHE B 1 23  ? -8.309  11.516  -5.350  0.670 21.640  0 23  PHE 2 CE2 1 ? 
ATOM   1929 C CZ  . PHE B 1 23  ? -7.436  10.681  -4.685  0.670 20.860  0 23  PHE 2 CZ  1 ? 
ATOM   1930 N N   . VAL B 1 24  ? -12.089 14.410  -3.537  0.670 16.690  0 24  VAL 2 N   1 ? 
ATOM   1931 C CA  . VAL B 1 24  ? -13.097 14.391  -4.620  0.670 16.170  0 24  VAL 2 CA  1 ? 
ATOM   1932 C C   . VAL B 1 24  ? -12.631 15.400  -5.660  0.670 17.590  0 24  VAL 2 C   1 ? 
ATOM   1933 O O   . VAL B 1 24  ? -12.320 16.565  -5.271  0.670 15.650  0 24  VAL 2 O   1 ? 
ATOM   1934 C CB  . VAL B 1 24  ? -14.526 14.727  -4.150  0.670 16.980  0 24  VAL 2 CB  1 ? 
ATOM   1935 C CG1 . VAL B 1 24  ? -15.490 14.753  -5.331  0.670 19.230  0 24  VAL 2 CG1 1 ? 
ATOM   1936 C CG2 . VAL B 1 24  ? -15.036 13.786  -3.056  0.670 17.100  0 24  VAL 2 CG2 1 ? 
ATOM   1937 N N   . ILE B 1 25  ? -12.585 14.966  -6.924  0.670 16.090  0 25  ILE 2 N   1 ? 
ATOM   1938 C CA  . ILE B 1 25  ? -12.128 15.820  -8.055  0.670 18.040  0 25  ILE 2 CA  1 ? 
ATOM   1939 C C   . ILE B 1 25  ? -13.146 15.670  -9.188  0.670 18.240  0 25  ILE 2 C   1 ? 
ATOM   1940 O O   . ILE B 1 25  ? -13.476 14.514  -9.522  0.670 18.780  0 25  ILE 2 O   1 ? 
ATOM   1941 C CB  . ILE B 1 25  ? -10.685 15.482  -8.507  0.670 19.550  0 25  ILE 2 CB  1 ? 
ATOM   1942 C CG1 . ILE B 1 25  ? -9.695  15.579  -7.351  0.670 20.080  0 25  ILE 2 CG1 1 ? 
ATOM   1943 C CG2 . ILE B 1 25  ? -10.279 16.383  -9.684  0.670 18.780  0 25  ILE 2 CG2 1 ? 
ATOM   1944 C CD1 . ILE B 1 25  ? -8.331  14.972  -7.610  0.670 20.080  0 25  ILE 2 CD1 1 ? 
ATOM   1945 N N   . ASP B 1 26  ? -13.599 16.794  -9.743  0.670 18.190  0 26  ASP 2 N   1 ? 
ATOM   1946 C CA  . ASP B 1 26  ? -14.549 16.851  -10.882 0.670 20.480  0 26  ASP 2 CA  1 ? 
ATOM   1947 C C   . ASP B 1 26  ? -13.781 17.236  -12.138 0.670 21.320  0 26  ASP 2 C   1 ? 
ATOM   1948 O O   . ASP B 1 26  ? -12.787 17.977  -12.028 0.670 20.410  0 26  ASP 2 O   1 ? 
ATOM   1949 C CB  . ASP B 1 26  ? -15.675 17.871  -10.681 0.670 24.150  0 26  ASP 2 CB  1 ? 
ATOM   1950 C CG  . ASP B 1 26  ? -16.789 17.336  -9.813  0.670 28.170  0 26  ASP 2 CG  1 ? 
ATOM   1951 O OD1 . ASP B 1 26  ? -16.850 16.096  -9.657  0.670 29.400  0 26  ASP 2 OD1 1 ? 
ATOM   1952 O OD2 . ASP B 1 26  ? -17.587 18.160  -9.294  0.670 30.720  0 26  ASP 2 OD2 1 ? 
ATOM   1953 N N   . GLY B 1 27  ? -14.213 16.699  -13.271 0.670 21.510  0 27  GLY 2 N   1 ? 
ATOM   1954 C CA  . GLY B 1 27  ? -13.581 16.963  -14.566 0.670 20.850  0 27  GLY 2 CA  1 ? 
ATOM   1955 C C   . GLY B 1 27  ? -14.630 17.289  -15.604 0.670 21.060  0 27  GLY 2 C   1 ? 
ATOM   1956 O O   . GLY B 1 27  ? -15.701 16.671  -15.589 0.670 20.150  0 27  GLY 2 O   1 ? 
ATOM   1957 N N   . ASP B 1 28  ? -14.259 18.147  -16.542 0.670 20.770  0 28  ASP 2 N   1 ? 
ATOM   1958 C CA  . ASP B 1 28  ? -15.096 18.583  -17.666 0.670 21.340  0 28  ASP 2 CA  1 ? 
ATOM   1959 C C   . ASP B 1 28  ? -14.159 18.788  -18.857 0.670 18.860  0 28  ASP 2 C   1 ? 
ATOM   1960 O O   . ASP B 1 28  ? -13.169 19.548  -18.718 0.670 19.350  0 28  ASP 2 O   1 ? 
ATOM   1961 C CB  . ASP B 1 28  ? -15.867 19.831  -17.243 0.670 27.880  0 28  ASP 2 CB  1 ? 
ATOM   1962 C CG  . ASP B 1 28  ? -16.686 20.378  -18.382 0.670 32.490  0 28  ASP 2 CG  1 ? 
ATOM   1963 O OD1 . ASP B 1 28  ? -17.663 19.696  -18.765 0.670 41.030  0 28  ASP 2 OD1 1 ? 
ATOM   1964 O OD2 . ASP B 1 28  ? -16.287 21.416  -18.934 0.670 41.840  0 28  ASP 2 OD2 1 ? 
ATOM   1965 N N   . GLY B 1 29  ? -14.415 18.144  -19.988 0.670 16.880  0 29  GLY 2 N   1 ? 
ATOM   1966 C CA  . GLY B 1 29  ? -13.504 18.336  -21.131 0.670 16.940  0 29  GLY 2 CA  1 ? 
ATOM   1967 C C   . GLY B 1 29  ? -14.118 17.944  -22.448 0.670 18.010  0 29  GLY 2 C   1 ? 
ATOM   1968 O O   . GLY B 1 29  ? -15.334 17.639  -22.506 0.670 17.410  0 29  GLY 2 O   1 ? 
ATOM   1969 N N   . THR B 1 30  ? -13.283 17.894  -23.480 0.670 18.140  0 30  THR 2 N   1 ? 
ATOM   1970 C CA  . THR B 1 30  ? -13.719 17.544  -24.852 0.670 19.630  0 30  THR 2 CA  1 ? 
ATOM   1971 C C   . THR B 1 30  ? -12.609 16.708  -25.478 0.670 20.260  0 30  THR 2 C   1 ? 
ATOM   1972 O O   . THR B 1 30  ? -11.452 16.766  -24.999 0.670 17.920  0 30  THR 2 O   1 ? 
ATOM   1973 C CB  . THR B 1 30  ? -13.994 18.765  -25.738 0.670 21.480  0 30  THR 2 CB  1 ? 
ATOM   1974 O OG1 . THR B 1 30  ? -12.720 19.349  -25.950 0.670 24.550  0 30  THR 2 OG1 1 ? 
ATOM   1975 C CG2 . THR B 1 30  ? -14.916 19.788  -25.121 0.670 23.220  0 30  THR 2 CG2 1 ? 
ATOM   1976 N N   . GLY B 1 31  ? -12.945 15.950  -26.505 0.670 19.650  0 31  GLY 2 N   1 ? 
ATOM   1977 C CA  . GLY B 1 31  ? -11.906 15.196  -27.212 0.670 21.470  0 31  GLY 2 CA  1 ? 
ATOM   1978 C C   . GLY B 1 31  ? -12.363 14.819  -28.593 0.670 20.140  0 31  GLY 2 C   1 ? 
ATOM   1979 O O   . GLY B 1 31  ? -13.525 15.125  -28.961 0.670 19.080  0 31  GLY 2 O   1 ? 
ATOM   1980 N N   . LYS B 1 32  ? -11.437 14.225  -29.318 0.670 20.860  0 32  LYS 2 N   1 ? 
ATOM   1981 C CA  . LYS B 1 32  ? -11.565 13.844  -30.744 0.670 22.570  0 32  LYS 2 CA  1 ? 
ATOM   1982 C C   . LYS B 1 32  ? -11.223 12.365  -30.826 0.670 20.390  0 32  LYS 2 C   1 ? 
ATOM   1983 O O   . LYS B 1 32  ? -10.060 12.030  -30.947 0.670 20.260  0 32  LYS 2 O   1 ? 
ATOM   1984 C CB  . LYS B 1 32  ? -10.632 14.731  -31.579 0.670 22.810  0 32  LYS 2 CB  1 ? 
ATOM   1985 C CG  . LYS B 1 32  ? -11.065 16.185  -31.648 0.670 29.790  0 32  LYS 2 CG  1 ? 
ATOM   1986 C CD  . LYS B 1 32  ? -10.092 17.078  -32.400 0.670 34.220  0 32  LYS 2 CD  1 ? 
ATOM   1987 C CE  . LYS B 1 32  ? -10.552 18.522  -32.464 0.670 39.870  0 32  LYS 2 CE  1 ? 
ATOM   1988 N NZ  . LYS B 1 32  ? -11.860 18.647  -33.153 0.670 42.850  0 32  LYS 2 NZ  1 ? 
ATOM   1989 N N   . PRO B 1 33  ? -12.208 11.454  -30.690 0.670 22.900  0 33  PRO 2 N   1 ? 
ATOM   1990 C CA  . PRO B 1 33  ? -11.923 10.017  -30.612 0.670 23.030  0 33  PRO 2 CA  1 ? 
ATOM   1991 C C   . PRO B 1 33  ? -11.041 9.488   -31.748 0.670 25.000  0 33  PRO 2 C   1 ? 
ATOM   1992 O O   . PRO B 1 33  ? -10.143 8.694   -31.471 0.670 25.320  0 33  PRO 2 O   1 ? 
ATOM   1993 C CB  . PRO B 1 33  ? -13.321 9.389   -30.619 0.670 23.350  0 33  PRO 2 CB  1 ? 
ATOM   1994 C CG  . PRO B 1 33  ? -14.171 10.448  -29.938 0.670 24.650  0 33  PRO 2 CG  1 ? 
ATOM   1995 C CD  . PRO B 1 33  ? -13.637 11.753  -30.486 0.670 23.500  0 33  PRO 2 CD  1 ? 
ATOM   1996 N N   . PHE B 1 34  ? -11.260 9.981   -32.974 0.670 26.610  0 34  PHE 2 N   1 ? 
ATOM   1997 C CA  . PHE B 1 34  ? -10.589 9.500   -34.215 0.670 25.600  0 34  PHE 2 CA  1 ? 
ATOM   1998 C C   . PHE B 1 34  ? -9.204  10.135  -34.418 0.670 27.760  0 34  PHE 2 C   1 ? 
ATOM   1999 O O   . PHE B 1 34  ? -8.429  9.589   -35.251 0.670 29.110  0 34  PHE 2 O   1 ? 
ATOM   2000 C CB  . PHE B 1 34  ? -11.499 9.757   -35.417 0.670 26.820  0 34  PHE 2 CB  1 ? 
ATOM   2001 C CG  . PHE B 1 34  ? -12.806 9.029   -35.303 0.670 28.140  0 34  PHE 2 CG  1 ? 
ATOM   2002 C CD1 . PHE B 1 34  ? -12.852 7.642   -35.442 0.670 28.520  0 34  PHE 2 CD1 1 ? 
ATOM   2003 C CD2 . PHE B 1 34  ? -13.967 9.709   -34.973 0.670 28.360  0 34  PHE 2 CD2 1 ? 
ATOM   2004 C CE1 . PHE B 1 34  ? -14.047 6.959   -35.296 0.670 29.300  0 34  PHE 2 CE1 1 ? 
ATOM   2005 C CE2 . PHE B 1 34  ? -15.160 9.015   -34.817 0.670 31.550  0 34  PHE 2 CE2 1 ? 
ATOM   2006 C CZ  . PHE B 1 34  ? -15.200 7.645   -34.987 0.670 28.420  0 34  PHE 2 CZ  1 ? 
ATOM   2007 N N   . GLU B 1 35  ? -8.883  11.234  -33.728 0.670 25.060  0 35  GLU 2 N   1 ? 
ATOM   2008 C CA  . GLU B 1 35  ? -7.546  11.877  -33.807 0.670 25.480  0 35  GLU 2 CA  1 ? 
ATOM   2009 C C   . GLU B 1 35  ? -6.693  11.418  -32.617 0.670 24.410  0 35  GLU 2 C   1 ? 
ATOM   2010 O O   . GLU B 1 35  ? -5.480  11.709  -32.621 0.670 24.400  0 35  GLU 2 O   1 ? 
ATOM   2011 C CB  . GLU B 1 35  ? -7.656  13.404  -33.817 0.670 32.590  0 35  GLU 2 CB  1 ? 
ATOM   2012 C CG  . GLU B 1 35  ? -8.186  13.976  -35.126 0.670 40.360  0 35  GLU 2 CG  1 ? 
ATOM   2013 C CD  . GLU B 1 35  ? -7.906  15.460  -35.355 0.670 46.070  0 35  GLU 2 CD  1 ? 
ATOM   2014 O OE1 . GLU B 1 35  ? -6.979  16.009  -34.712 0.670 50.700  0 35  GLU 2 OE1 1 ? 
ATOM   2015 O OE2 . GLU B 1 35  ? -8.612  16.071  -36.193 0.670 53.730  0 35  GLU 2 OE2 1 ? 
ATOM   2016 N N   . GLY B 1 36  ? -7.310  10.793  -31.612 0.670 20.890  0 36  GLY 2 N   1 ? 
ATOM   2017 C CA  . GLY B 1 36  ? -6.606  10.269  -30.427 0.670 20.920  0 36  GLY 2 CA  1 ? 
ATOM   2018 C C   . GLY B 1 36  ? -6.160  11.387  -29.503 0.670 19.670  0 36  GLY 2 C   1 ? 
ATOM   2019 O O   . GLY B 1 36  ? -5.016  11.331  -29.015 0.670 21.030  0 36  GLY 2 O   1 ? 
ATOM   2020 N N   . LYS B 1 37  ? -7.027  12.366  -29.267 0.670 20.030  0 37  LYS 2 N   1 ? 
ATOM   2021 C CA  . LYS B 1 37  ? -6.685  13.576  -28.475 0.670 21.580  0 37  LYS 2 CA  1 ? 
ATOM   2022 C C   . LYS B 1 37  ? -7.824  13.880  -27.512 0.670 20.320  0 37  LYS 2 C   1 ? 
ATOM   2023 O O   . LYS B 1 37  ? -8.972  13.750  -27.948 0.670 21.020  0 37  LYS 2 O   1 ? 
ATOM   2024 C CB  . LYS B 1 37  ? -6.484  14.789  -29.385 0.670 24.690  0 37  LYS 2 CB  1 ? 
ATOM   2025 C CG  . LYS B 1 37  ? -5.371  14.615  -30.404 0.670 31.560  0 37  LYS 2 CG  1 ? 
ATOM   2026 C CD  . LYS B 1 37  ? -5.109  15.844  -31.253 0.670 37.090  0 37  LYS 2 CD  1 ? 
ATOM   2027 C CE  . LYS B 1 37  ? -3.790  15.731  -31.997 0.670 44.140  0 37  LYS 2 CE  1 ? 
ATOM   2028 N NZ  . LYS B 1 37  ? -3.505  16.954  -32.789 0.670 50.370  0 37  LYS 2 NZ  1 ? 
ATOM   2029 N N   . GLN B 1 38  ? -7.496  14.292  -26.280 0.670 19.090  0 38  GLN 2 N   1 ? 
ATOM   2030 C CA  . GLN B 1 38  ? -8.488  14.745  -25.280 0.670 17.800  0 38  GLN 2 CA  1 ? 
ATOM   2031 C C   . GLN B 1 38  ? -7.833  15.819  -24.400 0.670 18.300  0 38  GLN 2 C   1 ? 
ATOM   2032 O O   . GLN B 1 38  ? -6.595  15.842  -24.242 0.670 17.170  0 38  GLN 2 O   1 ? 
ATOM   2033 C CB  . GLN B 1 38  ? -9.016  13.548  -24.485 0.670 18.070  0 38  GLN 2 CB  1 ? 
ATOM   2034 C CG  . GLN B 1 38  ? -7.988  12.884  -23.563 0.670 18.390  0 38  GLN 2 CG  1 ? 
ATOM   2035 C CD  . GLN B 1 38  ? -8.521  11.624  -22.919 0.670 18.660  0 38  GLN 2 CD  1 ? 
ATOM   2036 O OE1 . GLN B 1 38  ? -8.058  10.520  -23.183 0.670 22.580  0 38  GLN 2 OE1 1 ? 
ATOM   2037 N NE2 . GLN B 1 38  ? -9.489  11.764  -22.045 0.670 16.860  0 38  GLN 2 NE2 1 ? 
ATOM   2038 N N   . SER B 1 39  ? -8.631  16.744  -23.903 0.670 18.990  0 39  SER 2 N   1 ? 
ATOM   2039 C CA  . SER B 1 39  ? -8.200  17.662  -22.838 0.670 20.970  0 39  SER 2 CA  1 ? 
ATOM   2040 C C   . SER B 1 39  ? -9.370  17.880  -21.883 0.670 20.940  0 39  SER 2 C   1 ? 
ATOM   2041 O O   . SER B 1 39  ? -10.540 17.622  -22.243 0.670 21.040  0 39  SER 2 O   1 ? 
ATOM   2042 C CB  . SER B 1 39  ? -7.654  18.930  -23.400 0.670 24.530  0 39  SER 2 CB  1 ? 
ATOM   2043 O OG  . SER B 1 39  ? -8.698  19.788  -23.752 0.670 30.930  0 39  SER 2 OG  1 ? 
ATOM   2044 N N   . MET B 1 40  ? -9.052  18.286  -20.672 0.670 18.890  0 40  MET 2 N   1 ? 
ATOM   2045 C CA  . MET B 1 40  ? -10.082 18.420  -19.641 0.670 20.320  0 40  MET 2 CA  1 ? 
ATOM   2046 C C   . MET B 1 40  ? -9.564  19.362  -18.566 0.670 18.190  0 40  MET 2 C   1 ? 
ATOM   2047 O O   . MET B 1 40  ? -8.329  19.456  -18.374 0.670 17.390  0 40  MET 2 O   1 ? 
ATOM   2048 C CB  . MET B 1 40  ? -10.435 17.061  -19.032 0.670 21.880  0 40  MET 2 CB  1 ? 
ATOM   2049 C CG  . MET B 1 40  ? -9.301  16.360  -18.387 0.670 25.060  0 40  MET 2 CG  1 ? 
ATOM   2050 S SD  . MET B 1 40  ? -9.784  14.635  -18.018 0.670 32.470  0 40  MET 2 SD  1 ? 
ATOM   2051 C CE  . MET B 1 40  ? -9.668  13.880  -19.633 0.670 29.350  0 40  MET 2 CE  1 ? 
ATOM   2052 N N   . ASP B 1 41  ? -10.501 20.072  -17.970 0.670 17.050  0 41  ASP 2 N   1 ? 
ATOM   2053 C CA  . ASP B 1 41  ? -10.269 20.938  -16.799 0.670 18.870  0 41  ASP 2 CA  1 ? 
ATOM   2054 C C   . ASP B 1 41  ? -10.691 20.143  -15.575 0.670 18.290  0 41  ASP 2 C   1 ? 
ATOM   2055 O O   . ASP B 1 41  ? -11.810 19.602  -15.592 0.670 17.170  0 41  ASP 2 O   1 ? 
ATOM   2056 C CB  . ASP B 1 41  ? -11.046 22.233  -16.946 0.670 20.430  0 41  ASP 2 CB  1 ? 
ATOM   2057 C CG  . ASP B 1 41  ? -10.525 23.015  -18.125 0.670 23.360  0 41  ASP 2 CG  1 ? 
ATOM   2058 O OD1 . ASP B 1 41  ? -9.264  23.119  -18.286 0.670 22.320  0 41  ASP 2 OD1 1 ? 
ATOM   2059 O OD2 . ASP B 1 41  ? -11.361 23.482  -18.860 0.670 24.530  0 41  ASP 2 OD2 1 ? 
ATOM   2060 N N   . LEU B 1 42  ? -9.798  20.069  -14.591 0.670 17.420  0 42  LEU 2 N   1 ? 
ATOM   2061 C CA  . LEU B 1 42  ? -10.016 19.310  -13.352 0.670 18.520  0 42  LEU 2 CA  1 ? 
ATOM   2062 C C   . LEU B 1 42  ? -10.094 20.307  -12.197 0.670 17.610  0 42  LEU 2 C   1 ? 
ATOM   2063 O O   . LEU B 1 42  ? -9.356  21.308  -12.221 0.670 17.920  0 42  LEU 2 O   1 ? 
ATOM   2064 C CB  . LEU B 1 42  ? -8.856  18.335  -13.190 0.670 20.670  0 42  LEU 2 CB  1 ? 
ATOM   2065 C CG  . LEU B 1 42  ? -8.692  17.355  -14.354 0.670 22.260  0 42  LEU 2 CG  1 ? 
ATOM   2066 C CD1 . LEU B 1 42  ? -7.356  16.641  -14.264 0.670 23.450  0 42  LEU 2 CD1 1 ? 
ATOM   2067 C CD2 . LEU B 1 42  ? -9.856  16.370  -14.357 0.670 22.410  0 42  LEU 2 CD2 1 ? 
ATOM   2068 N N   . GLU B 1 43  ? -10.979 20.051  -11.244 0.670 18.610  0 43  GLU 2 N   1 ? 
ATOM   2069 C CA  . GLU B 1 43  ? -11.156 20.906  -10.047 0.670 19.740  0 43  GLU 2 CA  1 ? 
ATOM   2070 C C   . GLU B 1 43  ? -11.240 20.010  -8.818  0.670 17.530  0 43  GLU 2 C   1 ? 
ATOM   2071 O O   . GLU B 1 43  ? -12.138 19.134  -8.784  0.670 17.650  0 43  GLU 2 O   1 ? 
ATOM   2072 C CB  . GLU B 1 43  ? -12.414 21.762  -10.190 0.670 24.400  0 43  GLU 2 CB  1 ? 
ATOM   2073 C CG  . GLU B 1 43  ? -12.583 22.729  -9.025  0.670 28.680  0 43  GLU 2 CG  1 ? 
ATOM   2074 C CD  . GLU B 1 43  ? -13.138 24.106  -9.368  0.670 31.090  0 43  GLU 2 CD  1 ? 
ATOM   2075 O OE1 . GLU B 1 43  ? -13.627 24.290  -10.515 0.670 30.980  0 43  GLU 2 OE1 1 ? 
ATOM   2076 O OE2 . GLU B 1 43  ? -13.083 24.980  -8.474  0.670 33.100  0 43  GLU 2 OE2 1 ? 
ATOM   2077 N N   . VAL B 1 44  ? -10.347 20.214  -7.852  0.670 17.100  0 44  VAL 2 N   1 ? 
ATOM   2078 C CA  . VAL B 1 44  ? -10.398 19.512  -6.549  0.670 16.020  0 44  VAL 2 CA  1 ? 
ATOM   2079 C C   . VAL B 1 44  ? -11.594 20.103  -5.796  0.670 16.200  0 44  VAL 2 C   1 ? 
ATOM   2080 O O   . VAL B 1 44  ? -11.596 21.311  -5.561  0.670 15.690  0 44  VAL 2 O   1 ? 
ATOM   2081 C CB  . VAL B 1 44  ? -9.083  19.632  -5.758  0.670 16.950  0 44  VAL 2 CB  1 ? 
ATOM   2082 C CG1 . VAL B 1 44  ? -9.220  18.931  -4.423  0.670 17.820  0 44  VAL 2 CG1 1 ? 
ATOM   2083 C CG2 . VAL B 1 44  ? -7.897  19.095  -6.523  0.670 17.650  0 44  VAL 2 CG2 1 ? 
ATOM   2084 N N   . LYS B 1 45  ? -12.583 19.280  -5.436  0.670 16.720  0 45  LYS 2 N   1 ? 
ATOM   2085 C CA  . LYS B 1 45  ? -13.847 19.719  -4.777  0.670 17.030  0 45  LYS 2 CA  1 ? 
ATOM   2086 C C   . LYS B 1 45  ? -13.781 19.486  -3.264  0.670 17.720  0 45  LYS 2 C   1 ? 
ATOM   2087 O O   . LYS B 1 45  ? -14.390 20.278  -2.521  0.670 19.850  0 45  LYS 2 O   1 ? 
ATOM   2088 C CB  . LYS B 1 45  ? -15.033 18.980  -5.398  0.670 19.040  0 45  LYS 2 CB  1 ? 
ATOM   2089 C CG  . LYS B 1 45  ? -15.378 19.420  -6.814  0.670 22.690  0 45  LYS 2 CG  1 ? 
ATOM   2090 C CD  . LYS B 1 45  ? -15.581 20.917  -6.931  0.670 27.390  0 45  LYS 2 CD  1 ? 
ATOM   2091 C CE  . LYS B 1 45  ? -15.842 21.411  -8.341  0.670 34.130  0 45  LYS 2 CE  1 ? 
ATOM   2092 N NZ  . LYS B 1 45  ? -17.245 21.179  -8.749  0.670 40.360  0 45  LYS 2 NZ  1 ? 
ATOM   2093 N N   . GLU B 1 46  ? -13.092 18.450  -2.814  0.670 17.090  0 46  GLU 2 N   1 ? 
ATOM   2094 C CA  . GLU B 1 46  ? -12.895 18.173  -1.365  0.670 19.310  0 46  GLU 2 CA  1 ? 
ATOM   2095 C C   . GLU B 1 46  ? -11.500 17.644  -1.100  0.670 18.350  0 46  GLU 2 C   1 ? 
ATOM   2096 O O   . GLU B 1 46  ? -11.033 16.891  -1.959  0.670 17.910  0 46  GLU 2 O   1 ? 
ATOM   2097 C CB  . GLU B 1 46  ? -13.811 17.051  -0.881  0.670 20.830  0 46  GLU 2 CB  1 ? 
ATOM   2098 C CG  . GLU B 1 46  ? -15.244 17.425  -0.936  0.670 25.200  0 46  GLU 2 CG  1 ? 
ATOM   2099 C CD  . GLU B 1 46  ? -16.186 16.380  -0.364  0.670 26.600  0 46  GLU 2 CD  1 ? 
ATOM   2100 O OE1 . GLU B 1 46  ? -15.720 15.411  0.286   0.670 25.580  0 46  GLU 2 OE1 1 ? 
ATOM   2101 O OE2 . GLU B 1 46  ? -17.374 16.542  -0.626  0.670 31.740  0 46  GLU 2 OE2 1 ? 
ATOM   2102 N N   . GLY B 1 47  ? -10.935 17.926  0.088   0.670 19.400  0 47  GLY 2 N   1 ? 
ATOM   2103 C CA  . GLY B 1 47  ? -9.614  17.423  0.548   0.670 19.980  0 47  GLY 2 CA  1 ? 
ATOM   2104 C C   . GLY B 1 47  ? -8.399  18.221  0.052   0.670 25.020  0 47  GLY 2 C   1 ? 
ATOM   2105 O O   . GLY B 1 47  ? -7.252  17.779  0.353   0.670 26.090  0 47  GLY 2 O   1 ? 
ATOM   2106 N N   . GLY B 1 48  ? -8.604  19.343  -0.676  0.670 21.040  0 48  GLY 2 N   1 ? 
ATOM   2107 C CA  . GLY B 1 48  ? -7.521  20.229  -1.136  0.670 20.280  0 48  GLY 2 CA  1 ? 
ATOM   2108 C C   . GLY B 1 48  ? -6.990  21.132  -0.022  0.670 21.360  0 48  GLY 2 C   1 ? 
ATOM   2109 O O   . GLY B 1 48  ? -7.716  21.473  0.917   0.670 20.360  0 48  GLY 2 O   1 ? 
ATOM   2110 N N   . PRO B 1 49  ? -5.722  21.588  -0.086  0.670 21.590  0 49  PRO 2 N   1 ? 
ATOM   2111 C CA  . PRO B 1 49  ? -4.773  21.202  -1.136  0.670 21.500  0 49  PRO 2 CA  1 ? 
ATOM   2112 C C   . PRO B 1 49  ? -4.268  19.776  -0.892  0.670 19.290  0 49  PRO 2 C   1 ? 
ATOM   2113 O O   . PRO B 1 49  ? -4.006  19.416  0.224   0.670 20.080  0 49  PRO 2 O   1 ? 
ATOM   2114 C CB  . PRO B 1 49  ? -3.642  22.232  -0.979  0.670 21.640  0 49  PRO 2 CB  1 ? 
ATOM   2115 C CG  . PRO B 1 49  ? -3.653  22.533  0.513   0.670 23.450  0 49  PRO 2 CG  1 ? 
ATOM   2116 C CD  . PRO B 1 49  ? -5.134  22.574  0.836   0.670 24.120  0 49  PRO 2 CD  1 ? 
ATOM   2117 N N   . LEU B 1 50  ? -4.156  18.996  -1.954  0.670 19.470  0 50  LEU 2 N   1 ? 
ATOM   2118 C CA  . LEU B 1 50  ? -3.720  17.582  -1.889  0.670 19.490  0 50  LEU 2 CA  1 ? 
ATOM   2119 C C   . LEU B 1 50  ? -2.300  17.527  -1.355  0.670 18.180  0 50  LEU 2 C   1 ? 
ATOM   2120 O O   . LEU B 1 50  ? -1.445  18.277  -1.811  0.670 18.770  0 50  LEU 2 O   1 ? 
ATOM   2121 C CB  . LEU B 1 50  ? -3.755  16.946  -3.281  0.670 19.540  0 50  LEU 2 CB  1 ? 
ATOM   2122 C CG  . LEU B 1 50  ? -5.103  16.908  -3.987  0.670 20.150  0 50  LEU 2 CG  1 ? 
ATOM   2123 C CD1 . LEU B 1 50  ? -4.925  16.318  -5.376  0.670 22.850  0 50  LEU 2 CD1 1 ? 
ATOM   2124 C CD2 . LEU B 1 50  ? -6.126  16.130  -3.184  0.670 19.760  0 50  LEU 2 CD2 1 ? 
ATOM   2125 N N   . PRO B 1 51  ? -2.021  16.649  -0.369  0.670 20.560  0 51  PRO 2 N   1 ? 
ATOM   2126 C CA  . PRO B 1 51  ? -0.671  16.502  0.189   0.670 20.900  0 51  PRO 2 CA  1 ? 
ATOM   2127 C C   . PRO B 1 51  ? 0.267   15.548  -0.560  0.670 20.580  0 51  PRO 2 C   1 ? 
ATOM   2128 O O   . PRO B 1 51  ? 1.284   15.179  -0.001  0.670 21.740  0 51  PRO 2 O   1 ? 
ATOM   2129 C CB  . PRO B 1 51  ? -0.968  15.940  1.582   0.670 21.260  0 51  PRO 2 CB  1 ? 
ATOM   2130 C CG  . PRO B 1 51  ? -2.183  15.083  1.350   0.670 22.310  0 51  PRO 2 CG  1 ? 
ATOM   2131 C CD  . PRO B 1 51  ? -3.019  15.846  0.349   0.670 22.790  0 51  PRO 2 CD  1 ? 
ATOM   2132 N N   . PHE B 1 52  ? -0.059  15.192  -1.801  0.670 19.260  0 52  PHE 2 N   1 ? 
ATOM   2133 C CA  . PHE B 1 52  ? 0.777   14.296  -2.631  0.670 18.560  0 52  PHE 2 CA  1 ? 
ATOM   2134 C C   . PHE B 1 52  ? 0.831   14.842  -4.065  0.670 16.720  0 52  PHE 2 C   1 ? 
ATOM   2135 O O   . PHE B 1 52  ? 0.009   15.723  -4.423  0.670 16.130  0 52  PHE 2 O   1 ? 
ATOM   2136 C CB  . PHE B 1 52  ? 0.236   12.869  -2.567  0.670 18.170  0 52  PHE 2 CB  1 ? 
ATOM   2137 C CG  . PHE B 1 52  ? -1.182  12.741  -3.041  0.670 18.930  0 52  PHE 2 CG  1 ? 
ATOM   2138 C CD1 . PHE B 1 52  ? -1.467  12.672  -4.386  0.670 19.520  0 52  PHE 2 CD1 1 ? 
ATOM   2139 C CD2 . PHE B 1 52  ? -2.245  12.760  -2.148  0.670 21.230  0 52  PHE 2 CD2 1 ? 
ATOM   2140 C CE1 . PHE B 1 52  ? -2.776  12.595  -4.835  0.670 20.960  0 52  PHE 2 CE1 1 ? 
ATOM   2141 C CE2 . PHE B 1 52  ? -3.554  12.710  -2.596  0.670 20.800  0 52  PHE 2 CE2 1 ? 
ATOM   2142 C CZ  . PHE B 1 52  ? -3.823  12.626  -3.943  0.670 21.190  0 52  PHE 2 CZ  1 ? 
ATOM   2143 N N   . ALA B 1 53  ? 1.764   14.321  -4.860  0.670 16.690  0 53  ALA 2 N   1 ? 
ATOM   2144 C CA  . ALA B 1 53  ? 2.032   14.753  -6.250  0.670 16.730  0 53  ALA 2 CA  1 ? 
ATOM   2145 C C   . ALA B 1 53  ? 0.801   14.475  -7.113  0.670 18.460  0 53  ALA 2 C   1 ? 
ATOM   2146 O O   . ALA B 1 53  ? 0.378   13.297  -7.208  0.670 19.950  0 53  ALA 2 O   1 ? 
ATOM   2147 C CB  . ALA B 1 53  ? 3.259   14.059  -6.781  0.670 17.450  0 53  ALA 2 CB  1 ? 
ATOM   2148 N N   . PHE B 1 54  ? 0.271   15.509  -7.768  0.670 17.670  0 54  PHE 2 N   1 ? 
ATOM   2149 C CA  . PHE B 1 54  ? -0.933  15.416  -8.630  0.670 18.200  0 54  PHE 2 CA  1 ? 
ATOM   2150 C C   . PHE B 1 54  ? -0.670  14.386  -9.733  0.670 17.050  0 54  PHE 2 C   1 ? 
ATOM   2151 O O   . PHE B 1 54  ? -1.577  13.651  -10.075 0.670 16.220  0 54  PHE 2 O   1 ? 
ATOM   2152 C CB  . PHE B 1 54  ? -1.316  16.759  -9.257  0.670 17.100  0 54  PHE 2 CB  1 ? 
ATOM   2153 C CG  . PHE B 1 54  ? -2.751  16.805  -9.718  0.670 18.860  0 54  PHE 2 CG  1 ? 
ATOM   2154 C CD1 . PHE B 1 54  ? -3.783  17.057  -8.816  0.670 19.050  0 54  PHE 2 CD1 1 ? 
ATOM   2155 C CD2 . PHE B 1 54  ? -3.091  16.498  -11.029 0.670 17.720  0 54  PHE 2 CD2 1 ? 
ATOM   2156 C CE1 . PHE B 1 54  ? -5.102  17.086  -9.238  0.670 19.090  0 54  PHE 2 CE1 1 ? 
ATOM   2157 C CE2 . PHE B 1 54  ? -4.405  16.559  -11.453 0.670 18.370  0 54  PHE 2 CE2 1 ? 
ATOM   2158 C CZ  . PHE B 1 54  ? -5.408  16.821  -10.555 0.670 19.030  0 54  PHE 2 CZ  1 ? 
ATOM   2159 N N   . ASP B 1 55  ? 0.572   14.322  -10.229 0.670 17.880  0 55  ASP 2 N   1 ? 
ATOM   2160 C CA  . ASP B 1 55  ? 0.969   13.439  -11.357 0.670 16.710  0 55  ASP 2 CA  1 ? 
ATOM   2161 C C   . ASP B 1 55  ? 0.526   11.987  -11.144 0.670 16.770  0 55  ASP 2 C   1 ? 
ATOM   2162 O O   . ASP B 1 55  ? 0.282   11.344  -12.143 0.670 17.410  0 55  ASP 2 O   1 ? 
ATOM   2163 C CB  . ASP B 1 55  ? 2.479   13.489  -11.601 0.670 16.810  0 55  ASP 2 CB  1 ? 
ATOM   2164 C CG  . ASP B 1 55  ? 2.957   14.789  -12.232 0.670 17.130  0 55  ASP 2 CG  1 ? 
ATOM   2165 O OD1 . ASP B 1 55  ? 2.295   15.263  -13.191 0.670 17.950  0 55  ASP 2 OD1 1 ? 
ATOM   2166 O OD2 . ASP B 1 55  ? 3.979   15.307  -11.771 0.670 18.340  0 55  ASP 2 OD2 1 ? 
ATOM   2167 N N   . ILE B 1 56  ? 0.466   11.447  -9.924  0.670 16.730  0 56  ILE 2 N   1 ? 
ATOM   2168 C CA  . ILE B 1 56  ? 0.102   10.006  -9.743  0.670 17.570  0 56  ILE 2 CA  1 ? 
ATOM   2169 C C   . ILE B 1 56  ? -1.335  9.762   -10.222 0.670 17.370  0 56  ILE 2 C   1 ? 
ATOM   2170 O O   . ILE B 1 56  ? -1.608  8.650   -10.681 0.670 19.090  0 56  ILE 2 O   1 ? 
ATOM   2171 C CB  . ILE B 1 56  ? 0.329   9.459   -8.320  0.670 18.020  0 56  ILE 2 CB  1 ? 
ATOM   2172 C CG1 . ILE B 1 56  ? -0.539  10.122  -7.247  0.670 20.260  0 56  ILE 2 CG1 1 ? 
ATOM   2173 C CG2 . ILE B 1 56  ? 1.811   9.510   -7.993  0.670 20.090  0 56  ILE 2 CG2 1 ? 
ATOM   2174 C CD1 . ILE B 1 56  ? -0.673  9.286   -5.986  0.670 20.170  0 56  ILE 2 CD1 1 ? 
ATOM   2175 N N   . LEU B 1 57  ? -2.180  10.781  -10.231 0.670 15.460  0 57  LEU 2 N   1 ? 
ATOM   2176 C CA  . LEU B 1 57  ? -3.603  10.644  -10.579 0.670 16.080  0 57  LEU 2 CA  1 ? 
ATOM   2177 C C   . LEU B 1 57  ? -3.854  10.685  -12.093 0.670 15.710  0 57  LEU 2 C   1 ? 
ATOM   2178 O O   . LEU B 1 57  ? -4.958  10.299  -12.483 0.670 15.280  0 57  LEU 2 O   1 ? 
ATOM   2179 C CB  . LEU B 1 57  ? -4.367  11.802  -9.928  0.670 16.380  0 57  LEU 2 CB  1 ? 
ATOM   2180 C CG  . LEU B 1 57  ? -4.315  11.906  -8.419  0.670 17.460  0 57  LEU 2 CG  1 ? 
ATOM   2181 C CD1 . LEU B 1 57  ? -5.130  13.123  -8.018  0.670 18.460  0 57  LEU 2 CD1 1 ? 
ATOM   2182 C CD2 . LEU B 1 57  ? -4.833  10.659  -7.729  0.670 17.770  0 57  LEU 2 CD2 1 ? 
ATOM   2183 N N   . THR B 1 58  ? -2.974  11.248  -12.911 0.670 14.680  0 58  THR 2 N   1 ? 
ATOM   2184 C CA  . THR B 1 58  ? -3.448  11.838  -14.198 0.670 15.660  0 58  THR 2 CA  1 ? 
ATOM   2185 C C   . THR B 1 58  ? -3.857  10.747  -15.198 0.670 15.980  0 58  THR 2 C   1 ? 
ATOM   2186 O O   . THR B 1 58  ? -4.702  11.034  -16.079 0.670 17.970  0 58  THR 2 O   1 ? 
ATOM   2187 C CB  . THR B 1 58  ? -2.430  12.815  -14.800 0.670 15.180  0 58  THR 2 CB  1 ? 
ATOM   2188 O OG1 . THR B 1 58  ? -1.155  12.191  -14.950 0.670 15.970  0 58  THR 2 OG1 1 ? 
ATOM   2189 C CG2 . THR B 1 58  ? -2.312  14.068  -13.968 0.670 15.440  0 58  THR 2 CG2 1 ? 
ATOM   2190 N N   . THR B 1 59  ? -3.267  9.560   -15.164 0.670 17.330  0 59  THR 2 N   1 ? 
ATOM   2191 C CA  . THR B 1 59  ? -3.683  8.505   -16.131 0.670 17.840  0 59  THR 2 CA  1 ? 
ATOM   2192 C C   . THR B 1 59  ? -5.058  7.946   -15.753 0.670 17.130  0 59  THR 2 C   1 ? 
ATOM   2193 O O   . THR B 1 59  ? -5.694  7.343   -16.647 0.670 15.800  0 59  THR 2 O   1 ? 
ATOM   2194 C CB  . THR B 1 59  ? -2.631  7.416   -16.326 0.670 18.920  0 59  THR 2 CB  1 ? 
ATOM   2195 O OG1 . THR B 1 59  ? -2.590  6.657   -15.122 0.670 18.480  0 59  THR 2 OG1 1 ? 
ATOM   2196 C CG2 . THR B 1 59  ? -1.296  8.009   -16.720 0.670 18.100  0 59  THR 2 CG2 1 ? 
ATOM   2197 N N   . ALA B 1 60  ? -5.554  8.195   -14.534 0.670 16.550  0 60  ALA 2 N   1 ? 
ATOM   2198 C CA  . ALA B 1 60  ? -6.919  7.768   -14.159 0.670 16.770  0 60  ALA 2 CA  1 ? 
ATOM   2199 C C   . ALA B 1 60  ? -7.956  8.723   -14.754 0.670 17.400  0 60  ALA 2 C   1 ? 
ATOM   2200 O O   . ALA B 1 60  ? -9.027  8.207   -15.059 0.670 17.480  0 60  ALA 2 O   1 ? 
ATOM   2201 C CB  . ALA B 1 60  ? -7.102  7.582   -12.673 0.670 17.370  0 60  ALA 2 CB  1 ? 
ATOM   2202 N N   . PHE B 1 61  ? -7.435  9.949   -14.968 0.670 17.040  0 61  PHE 2 N   1 ? 
ATOM   2203 C CA  . PHE B 1 61  ? -8.362  10.921  -15.612 0.670 18.050  0 61  PHE 2 CA  1 ? 
ATOM   2204 C C   . PHE B 1 61  ? -8.450  10.669  -17.116 0.670 18.490  0 61  PHE 2 C   1 ? 
ATOM   2205 O O   . PHE B 1 61  ? -9.468  10.672  -17.764 0.670 19.870  0 61  PHE 2 O   1 ? 
ATOM   2206 C CB  . PHE B 1 61  ? -7.914  12.366  -15.377 0.670 20.170  0 61  PHE 2 CB  1 ? 
ATOM   2207 C CG  . PHE B 1 61  ? -7.977  12.743  -13.922 0.670 20.780  0 61  PHE 2 CG  1 ? 
ATOM   2208 C CD1 . PHE B 1 61  ? -9.173  12.656  -13.241 0.670 24.100  0 61  PHE 2 CD1 1 ? 
ATOM   2209 C CD2 . PHE B 1 61  ? -6.867  13.206  -13.247 0.670 23.020  0 61  PHE 2 CD2 1 ? 
ATOM   2210 C CE1 . PHE B 1 61  ? -9.248  13.020  -11.904 0.670 22.800  0 61  PHE 2 CE1 1 ? 
ATOM   2211 C CE2 . PHE B 1 61  ? -6.949  13.580  -11.917 0.670 21.880  0 61  PHE 2 CE2 1 ? 
ATOM   2212 C CZ  . PHE B 1 61  ? -8.132  13.452  -11.248 0.670 21.800  0 61  PHE 2 CZ  1 ? 
HETATM 2213 N N1  . PIA B 1 62  ? -7.105  10.431  -17.674 0.670 16.700  0 64  PIA 2 N1  1 ? 
HETATM 2214 C CA1 . PIA B 1 62  ? -7.156  10.208  -19.139 0.670 16.990  0 64  PIA 2 CA1 1 ? 
HETATM 2215 C CB1 . PIA B 1 62  ? -6.455  11.325  -19.917 0.670 16.170  0 64  PIA 2 CB1 1 ? 
HETATM 2216 C C1  . PIA B 1 62  ? -6.550  8.871   -19.361 0.670 17.930  0 64  PIA 2 C1  1 ? 
HETATM 2217 N N2  . PIA B 1 62  ? -5.341  8.768   -19.820 0.670 17.650  0 64  PIA 2 N2  1 ? 
HETATM 2218 N N3  . PIA B 1 62  ? -7.124  7.651   -19.050 0.670 19.050  0 64  PIA 2 N3  1 ? 
HETATM 2219 C C2  . PIA B 1 62  ? -6.203  6.666   -19.326 0.670 19.830  0 64  PIA 2 C2  1 ? 
HETATM 2220 O O2  . PIA B 1 62  ? -6.416  5.472   -19.192 0.670 18.920  0 64  PIA 2 O2  1 ? 
HETATM 2221 C CA2 . PIA B 1 62  ? -4.978  7.417   -19.724 0.670 19.490  0 64  PIA 2 CA2 1 ? 
HETATM 2222 C CA3 . PIA B 1 62  ? -8.415  7.442   -18.396 0.670 18.400  0 64  PIA 2 CA3 1 ? 
HETATM 2223 C C3  . PIA B 1 62  ? -9.507  6.868   -19.292 0.670 17.250  0 64  PIA 2 C3  1 ? 
HETATM 2224 O O3  . PIA B 1 62  ? -10.571 6.425   -18.838 0.670 16.520  0 64  PIA 2 O3  1 ? 
HETATM 2225 C CB2 . PIA B 1 62  ? -3.774  6.885   -20.000 0.670 21.000  0 64  PIA 2 CB2 1 ? 
HETATM 2226 C CG2 . PIA B 1 62  ? -3.190  5.564   -19.830 0.670 22.590  0 64  PIA 2 CG2 1 ? 
HETATM 2227 C CD1 . PIA B 1 62  ? -1.821  5.521   -19.572 0.670 25.400  0 64  PIA 2 CD1 1 ? 
HETATM 2228 C CD2 . PIA B 1 62  ? -3.847  4.346   -20.020 0.670 24.220  0 64  PIA 2 CD2 1 ? 
HETATM 2229 C CE1 . PIA B 1 62  ? -1.148  4.323   -19.453 0.670 25.710  0 64  PIA 2 CE1 1 ? 
HETATM 2230 C CE2 . PIA B 1 62  ? -3.180  3.144   -19.919 0.670 25.800  0 64  PIA 2 CE2 1 ? 
HETATM 2231 C CZ  . PIA B 1 62  ? -1.830  3.133   -19.616 0.670 27.160  0 64  PIA 2 CZ  1 ? 
HETATM 2232 O OH  . PIA B 1 62  ? -1.160  1.955   -19.517 0.670 33.880  0 64  PIA 2 OH  1 ? 
ATOM   2233 N N   . ASN B 1 63  ? -9.261  6.974   -20.938 0.670 15.230  0 65  ASN 2 N   1 ? 
ATOM   2234 C CA  . ASN B 1 63  ? -10.330 6.415   -21.716 0.670 16.120  0 65  ASN 2 CA  1 ? 
ATOM   2235 C C   . ASN B 1 63  ? -9.746  6.197   -23.117 0.670 16.330  0 65  ASN 2 C   1 ? 
ATOM   2236 O O   . ASN B 1 63  ? -9.585  7.177   -23.876 0.670 15.620  0 65  ASN 2 O   1 ? 
ATOM   2237 C CB  . ASN B 1 63  ? -11.548 7.342   -21.682 0.670 15.570  0 65  ASN 2 CB  1 ? 
ATOM   2238 C CG  . ASN B 1 63  ? -12.708 6.852   -22.510 0.670 15.370  0 65  ASN 2 CG  1 ? 
ATOM   2239 O OD1 . ASN B 1 63  ? -12.635 5.786   -23.125 0.670 15.560  0 65  ASN 2 OD1 1 ? 
ATOM   2240 N ND2 . ASN B 1 63  ? -13.741 7.673   -22.612 0.670 15.740  0 65  ASN 2 ND2 1 ? 
ATOM   2241 N N   . ARG B 1 64  ? -9.406  4.948   -23.420 0.670 16.660  0 66  ARG 2 N   1 ? 
ATOM   2242 C CA  . ARG B 1 64  ? -8.683  4.545   -24.643 0.670 17.350  0 66  ARG 2 CA  1 ? 
ATOM   2243 C C   . ARG B 1 64  ? -9.620  4.633   -25.866 0.670 18.990  0 66  ARG 2 C   1 ? 
ATOM   2244 O O   . ARG B 1 64  ? -9.151  4.308   -26.966 0.670 17.970  0 66  ARG 2 O   1 ? 
ATOM   2245 C CB  . ARG B 1 64  ? -8.086  3.143   -24.408 0.670 17.810  0 66  ARG 2 CB  1 ? 
ATOM   2246 C CG  . ARG B 1 64  ? -6.761  3.139   -23.656 0.670 17.960  0 66  ARG 2 CG  1 ? 
ATOM   2247 C CD  . ARG B 1 64  ? -5.601  3.638   -24.530 0.670 18.370  0 66  ARG 2 CD  1 ? 
ATOM   2248 N NE  . ARG B 1 64  ? -4.256  3.589   -23.942 0.670 18.180  0 66  ARG 2 NE  1 ? 
ATOM   2249 C CZ  . ARG B 1 64  ? -3.533  4.632   -23.553 0.670 17.580  0 66  ARG 2 CZ  1 ? 
ATOM   2250 N NH1 . ARG B 1 64  ? -3.995  5.874   -23.669 0.670 17.460  0 66  ARG 2 NH1 1 ? 
ATOM   2251 N NH2 . ARG B 1 64  ? -2.308  4.427   -23.083 0.670 18.670  0 66  ARG 2 NH2 1 ? 
ATOM   2252 N N   . VAL B 1 65  ? -10.882 5.090   -25.711 0.670 19.100  0 67  VAL 2 N   1 ? 
ATOM   2253 C CA  . VAL B 1 65  ? -11.707 5.571   -26.859 0.670 19.940  0 67  VAL 2 CA  1 ? 
ATOM   2254 C C   . VAL B 1 65  ? -10.979 6.717   -27.583 0.670 19.730  0 67  VAL 2 C   1 ? 
ATOM   2255 O O   . VAL B 1 65  ? -11.105 6.788   -28.809 0.670 19.200  0 67  VAL 2 O   1 ? 
ATOM   2256 C CB  . VAL B 1 65  ? -13.155 5.955   -26.482 0.670 22.810  0 67  VAL 2 CB  1 ? 
ATOM   2257 C CG1 . VAL B 1 65  ? -13.270 7.322   -25.845 0.670 24.880  0 67  VAL 2 CG1 1 ? 
ATOM   2258 C CG2 . VAL B 1 65  ? -14.058 5.901   -27.704 0.670 26.610  0 67  VAL 2 CG2 1 ? 
ATOM   2259 N N   . PHE B 1 66  ? -10.234 7.563   -26.859 0.670 19.810  0 68  PHE 2 N   1 ? 
ATOM   2260 C CA  . PHE B 1 66  ? -9.474  8.714   -27.413 0.670 19.580  0 68  PHE 2 CA  1 ? 
ATOM   2261 C C   . PHE B 1 66  ? -8.087  8.224   -27.848 0.670 19.980  0 68  PHE 2 C   1 ? 
ATOM   2262 O O   . PHE B 1 66  ? -7.071  8.653   -27.322 0.670 21.680  0 68  PHE 2 O   1 ? 
ATOM   2263 C CB  . PHE B 1 66  ? -9.423  9.879   -26.416 0.670 18.900  0 68  PHE 2 CB  1 ? 
ATOM   2264 C CG  . PHE B 1 66  ? -10.773 10.456  -26.088 0.670 20.080  0 68  PHE 2 CG  1 ? 
ATOM   2265 C CD1 . PHE B 1 66  ? -11.468 11.217  -27.022 0.670 21.080  0 68  PHE 2 CD1 1 ? 
ATOM   2266 C CD2 . PHE B 1 66  ? -11.365 10.209  -24.860 0.670 20.190  0 68  PHE 2 CD2 1 ? 
ATOM   2267 C CE1 . PHE B 1 66  ? -12.723 11.727  -26.723 0.670 23.200  0 68  PHE 2 CE1 1 ? 
ATOM   2268 C CE2 . PHE B 1 66  ? -12.621 10.715  -24.568 0.670 21.280  0 68  PHE 2 CE2 1 ? 
ATOM   2269 C CZ  . PHE B 1 66  ? -13.299 11.470  -25.496 0.670 23.140  0 68  PHE 2 CZ  1 ? 
ATOM   2270 N N   . ALA B 1 67  ? -8.058  7.331   -28.825 0.670 20.120  0 69  ALA 2 N   1 ? 
ATOM   2271 C CA  . ALA B 1 67  ? -6.831  6.749   -29.410 0.670 21.250  0 69  ALA 2 CA  1 ? 
ATOM   2272 C C   . ALA B 1 67  ? -7.077  6.571   -30.900 0.670 20.470  0 69  ALA 2 C   1 ? 
ATOM   2273 O O   . ALA B 1 67  ? -8.165  6.109   -31.247 0.670 22.480  0 69  ALA 2 O   1 ? 
ATOM   2274 C CB  . ALA B 1 67  ? -6.495  5.432   -28.774 0.670 22.270  0 69  ALA 2 CB  1 ? 
ATOM   2275 N N   . LYS B 1 68  ? -6.124  6.976   -31.733 0.670 21.550  0 70  LYS 2 N   1 ? 
ATOM   2276 C CA  . LYS B 1 68  ? -6.215  6.807   -33.204 0.670 22.170  0 70  LYS 2 CA  1 ? 
ATOM   2277 C C   . LYS B 1 68  ? -5.838  5.362   -33.517 0.670 22.540  0 70  LYS 2 C   1 ? 
ATOM   2278 O O   . LYS B 1 68  ? -4.635  4.998   -33.342 0.670 19.100  0 70  LYS 2 O   1 ? 
ATOM   2279 C CB  . LYS B 1 68  ? -5.309  7.810   -33.921 0.670 26.740  0 70  LYS 2 CB  1 ? 
ATOM   2280 C CG  . LYS B 1 68  ? -5.388  7.762   -35.446 0.670 32.720  0 70  LYS 2 CG  1 ? 
ATOM   2281 C CD  . LYS B 1 68  ? -4.646  8.875   -36.172 0.670 38.240  0 70  LYS 2 CD  1 ? 
ATOM   2282 C CE  . LYS B 1 68  ? -3.189  8.994   -35.764 0.670 46.240  0 70  LYS 2 CE  1 ? 
ATOM   2283 N NZ  . LYS B 1 68  ? -2.382  9.805   -36.719 0.670 52.480  0 70  LYS 2 NZ  1 ? 
ATOM   2284 N N   . TYR B 1 69  ? -6.826  4.579   -33.954 0.670 19.790  0 71  TYR 2 N   1 ? 
ATOM   2285 C CA  . TYR B 1 69  ? -6.643  3.176   -34.378 0.670 20.530  0 71  TYR 2 CA  1 ? 
ATOM   2286 C C   . TYR B 1 69  ? -6.635  3.137   -35.897 0.670 22.840  0 71  TYR 2 C   1 ? 
ATOM   2287 O O   . TYR B 1 69  ? -7.525  3.733   -36.512 0.670 22.640  0 71  TYR 2 O   1 ? 
ATOM   2288 C CB  . TYR B 1 69  ? -7.731  2.278   -33.804 0.670 19.930  0 71  TYR 2 CB  1 ? 
ATOM   2289 C CG  . TYR B 1 69  ? -7.363  1.643   -32.500 0.670 19.470  0 71  TYR 2 CG  1 ? 
ATOM   2290 C CD1 . TYR B 1 69  ? -7.463  2.364   -31.322 0.670 20.120  0 71  TYR 2 CD1 1 ? 
ATOM   2291 C CD2 . TYR B 1 69  ? -6.922  0.324   -32.440 0.670 19.800  0 71  TYR 2 CD2 1 ? 
ATOM   2292 C CE1 . TYR B 1 69  ? -7.109  1.799   -30.110 0.670 19.310  0 71  TYR 2 CE1 1 ? 
ATOM   2293 C CE2 . TYR B 1 69  ? -6.582  -0.259  -31.225 0.670 19.690  0 71  TYR 2 CE2 1 ? 
ATOM   2294 C CZ  . TYR B 1 69  ? -6.670  0.488   -30.059 0.670 19.310  0 71  TYR 2 CZ  1 ? 
ATOM   2295 O OH  . TYR B 1 69  ? -6.304  -0.040  -28.847 0.670 18.000  0 71  TYR 2 OH  1 ? 
ATOM   2296 N N   . PRO B 1 70  ? -5.622  2.481   -36.509 0.670 23.930  0 72  PRO 2 N   1 ? 
ATOM   2297 C CA  . PRO B 1 70  ? -5.608  2.218   -37.949 0.670 24.560  0 72  PRO 2 CA  1 ? 
ATOM   2298 C C   . PRO B 1 70  ? -6.631  1.122   -38.257 0.670 26.110  0 72  PRO 2 C   1 ? 
ATOM   2299 O O   . PRO B 1 70  ? -7.117  0.512   -37.300 0.670 25.630  0 72  PRO 2 O   1 ? 
ATOM   2300 C CB  . PRO B 1 70  ? -4.158  1.755   -38.191 0.670 25.510  0 72  PRO 2 CB  1 ? 
ATOM   2301 C CG  . PRO B 1 70  ? -3.784  1.058   -36.921 0.670 26.050  0 72  PRO 2 CG  1 ? 
ATOM   2302 C CD  . PRO B 1 70  ? -4.466  1.874   -35.831 0.670 24.510  0 72  PRO 2 CD  1 ? 
ATOM   2303 N N   . ASP B 1 71  ? -6.954  0.884   -39.542 0.670 27.510  0 73  ASP 2 N   1 ? 
ATOM   2304 C CA  . ASP B 1 71  ? -8.046  -0.058  -39.937 0.670 29.170  0 73  ASP 2 CA  1 ? 
ATOM   2305 C C   . ASP B 1 71  ? -7.655  -1.483  -39.590 0.670 26.350  0 73  ASP 2 C   1 ? 
ATOM   2306 O O   . ASP B 1 71  ? -8.548  -2.293  -39.320 0.670 29.140  0 73  ASP 2 O   1 ? 
ATOM   2307 C CB  . ASP B 1 71  ? -8.332  -0.119  -41.433 0.670 34.590  0 73  ASP 2 CB  1 ? 
ATOM   2308 C CG  . ASP B 1 71  ? -8.348  1.222   -42.130 0.670 38.000  0 73  ASP 2 CG  1 ? 
ATOM   2309 O OD1 . ASP B 1 71  ? -8.867  2.195   -41.537 0.670 38.610  0 73  ASP 2 OD1 1 ? 
ATOM   2310 O OD2 . ASP B 1 71  ? -7.862  1.260   -43.283 0.670 43.020  0 73  ASP 2 OD2 1 ? 
ATOM   2311 N N   . ASN B 1 72  ? -6.366  -1.788  -39.609 0.670 29.080  0 74  ASN 2 N   1 ? 
ATOM   2312 C CA  . ASN B 1 72  ? -5.886  -3.187  -39.513 0.670 28.780  0 74  ASN 2 CA  1 ? 
ATOM   2313 C C   . ASN B 1 72  ? -5.756  -3.628  -38.053 0.670 28.210  0 74  ASN 2 C   1 ? 
ATOM   2314 O O   . ASN B 1 72  ? -5.247  -4.747  -37.848 0.670 28.110  0 74  ASN 2 O   1 ? 
ATOM   2315 C CB  . ASN B 1 72  ? -4.554  -3.375  -40.232 0.670 33.150  0 74  ASN 2 CB  1 ? 
ATOM   2316 C CG  . ASN B 1 72  ? -3.433  -2.576  -39.618 0.670 35.930  0 74  ASN 2 CG  1 ? 
ATOM   2317 O OD1 . ASN B 1 72  ? -3.647  -1.466  -39.150 0.670 35.870  0 74  ASN 2 OD1 1 ? 
ATOM   2318 N ND2 . ASN B 1 72  ? -2.232  -3.130  -39.633 0.670 45.320  0 74  ASN 2 ND2 1 ? 
ATOM   2319 N N   . ILE B 1 73  ? -6.153  -2.806  -37.075 0.670 24.330  0 75  ILE 2 N   1 ? 
ATOM   2320 C CA  . ILE B 1 73  ? -6.287  -3.273  -35.656 0.670 23.810  0 75  ILE 2 CA  1 ? 
ATOM   2321 C C   . ILE B 1 73  ? -7.744  -3.100  -35.215 0.670 24.800  0 75  ILE 2 C   1 ? 
ATOM   2322 O O   . ILE B 1 73  ? -8.300  -1.997  -35.358 0.670 25.790  0 75  ILE 2 O   1 ? 
ATOM   2323 C CB  . ILE B 1 73  ? -5.318  -2.539  -34.712 0.670 25.640  0 75  ILE 2 CB  1 ? 
ATOM   2324 C CG1 . ILE B 1 73  ? -3.860  -2.602  -35.176 0.670 26.610  0 75  ILE 2 CG1 1 ? 
ATOM   2325 C CG2 . ILE B 1 73  ? -5.458  -3.071  -33.292 0.670 27.090  0 75  ILE 2 CG2 1 ? 
ATOM   2326 C CD1 . ILE B 1 73  ? -2.955  -1.571  -34.505 0.670 25.940  0 75  ILE 2 CD1 1 ? 
ATOM   2327 N N   . GLN B 1 74  ? -8.330  -4.156  -34.668 0.670 22.380  0 76  GLN 2 N   1 ? 
ATOM   2328 C CA  . GLN B 1 74  ? -9.639  -4.129  -33.982 0.670 21.620  0 76  GLN 2 CA  1 ? 
ATOM   2329 C C   . GLN B 1 74  ? -9.592  -3.053  -32.876 0.670 23.280  0 76  GLN 2 C   1 ? 
ATOM   2330 O O   . GLN B 1 74  ? -8.624  -3.031  -32.085 0.670 19.240  0 76  GLN 2 O   1 ? 
ATOM   2331 C CB  . GLN B 1 74  ? -9.940  -5.540  -33.500 0.670 24.060  0 76  GLN 2 CB  1 ? 
ATOM   2332 C CG  . GLN B 1 74  ? -11.124 -5.686  -32.559 0.670 25.260  0 76  GLN 2 CG  1 ? 
ATOM   2333 C CD  . GLN B 1 74  ? -12.474 -5.453  -33.189 0.670 30.850  0 76  GLN 2 CD  1 ? 
ATOM   2334 O OE1 . GLN B 1 74  ? -12.594 -5.121  -34.378 0.670 31.680  0 76  GLN 2 OE1 1 ? 
ATOM   2335 N NE2 . GLN B 1 74  ? -13.505 -5.636  -32.374 0.670 29.710  0 76  GLN 2 NE2 1 ? 
ATOM   2336 N N   . ASP B 1 75  ? -10.561 -2.132  -32.906 0.670 19.220  0 77  ASP 2 N   1 ? 
ATOM   2337 C CA  . ASP B 1 75  ? -10.722 -1.042  -31.909 0.670 19.640  0 77  ASP 2 CA  1 ? 
ATOM   2338 C C   . ASP B 1 75  ? -11.798 -1.470  -30.915 0.670 18.460  0 77  ASP 2 C   1 ? 
ATOM   2339 O O   . ASP B 1 75  ? -13.008 -1.195  -31.158 0.670 21.310  0 77  ASP 2 O   1 ? 
ATOM   2340 C CB  . ASP B 1 75  ? -11.069 0.259   -32.613 0.670 19.840  0 77  ASP 2 CB  1 ? 
ATOM   2341 C CG  . ASP B 1 75  ? -10.999 1.475   -31.713 0.670 19.390  0 77  ASP 2 CG  1 ? 
ATOM   2342 O OD1 . ASP B 1 75  ? -10.989 1.295   -30.491 0.670 18.090  0 77  ASP 2 OD1 1 ? 
ATOM   2343 O OD2 . ASP B 1 75  ? -10.993 2.571   -32.269 0.670 20.370  0 77  ASP 2 OD2 1 ? 
ATOM   2344 N N   . TYR B 1 76  ? -11.387 -2.198  -29.884 0.670 16.760  0 78  TYR 2 N   1 ? 
ATOM   2345 C CA  . TYR B 1 76  ? -12.276 -2.714  -28.822 0.670 17.470  0 78  TYR 2 CA  1 ? 
ATOM   2346 C C   . TYR B 1 76  ? -13.063 -1.554  -28.183 0.670 17.520  0 78  TYR 2 C   1 ? 
ATOM   2347 O O   . TYR B 1 76  ? -14.249 -1.703  -27.847 0.670 17.940  0 78  TYR 2 O   1 ? 
ATOM   2348 C CB  . TYR B 1 76  ? -11.396 -3.434  -27.807 0.670 18.760  0 78  TYR 2 CB  1 ? 
ATOM   2349 C CG  . TYR B 1 76  ? -12.117 -4.217  -26.756 0.670 18.970  0 78  TYR 2 CG  1 ? 
ATOM   2350 C CD1 . TYR B 1 76  ? -12.733 -5.415  -27.077 0.670 20.750  0 78  TYR 2 CD1 1 ? 
ATOM   2351 C CD2 . TYR B 1 76  ? -12.113 -3.824  -25.425 0.670 19.030  0 78  TYR 2 CD2 1 ? 
ATOM   2352 C CE1 . TYR B 1 76  ? -13.348 -6.185  -26.110 0.670 20.230  0 78  TYR 2 CE1 1 ? 
ATOM   2353 C CE2 . TYR B 1 76  ? -12.700 -4.602  -24.442 0.670 19.280  0 78  TYR 2 CE2 1 ? 
ATOM   2354 C CZ  . TYR B 1 76  ? -13.333 -5.781  -24.788 0.670 21.680  0 78  TYR 2 CZ  1 ? 
ATOM   2355 O OH  . TYR B 1 76  ? -13.967 -6.545  -23.834 0.670 22.210  0 78  TYR 2 OH  1 ? 
ATOM   2356 N N   . PHE B 1 77  ? -12.420 -0.400  -28.013 0.670 17.840  0 79  PHE 2 N   1 ? 
ATOM   2357 C CA  . PHE B 1 77  ? -12.957 0.698   -27.164 0.670 18.010  0 79  PHE 2 CA  1 ? 
ATOM   2358 C C   . PHE B 1 77  ? -14.133 1.334   -27.899 0.670 19.690  0 79  PHE 2 C   1 ? 
ATOM   2359 O O   . PHE B 1 77  ? -15.218 1.441   -27.312 0.670 20.240  0 79  PHE 2 O   1 ? 
ATOM   2360 C CB  . PHE B 1 77  ? -11.826 1.647   -26.747 0.670 17.590  0 79  PHE 2 CB  1 ? 
ATOM   2361 C CG  . PHE B 1 77  ? -10.681 0.919   -26.088 0.670 17.340  0 79  PHE 2 CG  1 ? 
ATOM   2362 C CD1 . PHE B 1 77  ? -10.846 0.369   -24.823 0.670 18.080  0 79  PHE 2 CD1 1 ? 
ATOM   2363 C CD2 . PHE B 1 77  ? -9.487  0.695   -26.749 0.670 18.500  0 79  PHE 2 CD2 1 ? 
ATOM   2364 C CE1 . PHE B 1 77  ? -9.835  -0.358  -24.231 0.670 17.770  0 79  PHE 2 CE1 1 ? 
ATOM   2365 C CE2 . PHE B 1 77  ? -8.468  -0.020  -26.143 0.670 19.510  0 79  PHE 2 CE2 1 ? 
ATOM   2366 C CZ  . PHE B 1 77  ? -8.645  -0.545  -24.888 0.670 19.600  0 79  PHE 2 CZ  1 ? 
ATOM   2367 N N   . LYS B 1 78  ? -13.958 1.711   -29.166 0.670 20.980  0 80  LYS 2 N   1 ? 
ATOM   2368 C CA  . LYS B 1 78  ? -15.056 2.354   -29.927 0.670 21.840  0 80  LYS 2 CA  1 ? 
ATOM   2369 C C   . LYS B 1 78  ? -16.202 1.345   -30.131 0.670 23.660  0 80  LYS 2 C   1 ? 
ATOM   2370 O O   . LYS B 1 78  ? -17.363 1.769   -30.049 0.670 25.250  0 80  LYS 2 O   1 ? 
ATOM   2371 C CB  . LYS B 1 78  ? -14.523 2.957   -31.230 0.670 21.660  0 80  LYS 2 CB  1 ? 
ATOM   2372 C CG  . LYS B 1 78  ? -13.552 4.106   -31.013 0.670 21.280  0 80  LYS 2 CG  1 ? 
ATOM   2373 C CD  . LYS B 1 78  ? -13.180 4.857   -32.271 0.670 20.470  0 80  LYS 2 CD  1 ? 
ATOM   2374 C CE  . LYS B 1 78  ? -12.188 5.983   -32.028 0.670 20.730  0 80  LYS 2 CE  1 ? 
ATOM   2375 N NZ  . LYS B 1 78  ? -10.888 5.477   -31.520 0.670 19.550  0 80  LYS 2 NZ  1 ? 
ATOM   2376 N N   . GLN B 1 79  ? -15.916 0.054   -30.329 0.670 24.830  0 81  GLN 2 N   1 ? 
ATOM   2377 C CA  . GLN B 1 79  ? -16.968 -1.000  -30.507 0.670 26.090  0 81  GLN 2 CA  1 ? 
ATOM   2378 C C   . GLN B 1 79  ? -17.711 -1.299  -29.194 0.670 23.600  0 81  GLN 2 C   1 ? 
ATOM   2379 O O   . GLN B 1 79  ? -18.756 -1.934  -29.254 0.670 22.730  0 81  GLN 2 O   1 ? 
ATOM   2380 C CB  . GLN B 1 79  ? -16.339 -2.294  -31.020 0.670 27.480  0 81  GLN 2 CB  1 ? 
ATOM   2381 C CG  . GLN B 1 79  ? -15.608 -2.140  -32.337 0.670 32.760  0 81  GLN 2 CG  1 ? 
ATOM   2382 C CD  . GLN B 1 79  ? -16.426 -2.719  -33.457 0.670 45.810  0 81  GLN 2 CD  1 ? 
ATOM   2383 O OE1 . GLN B 1 79  ? -15.970 -3.616  -34.179 0.670 58.730  0 81  GLN 2 OE1 1 ? 
ATOM   2384 N NE2 . GLN B 1 79  ? -17.671 -2.262  -33.549 0.670 47.250  0 81  GLN 2 NE2 1 ? 
ATOM   2385 N N   . SER B 1 80  ? -17.220 -0.846  -28.045 0.670 21.430  0 82  SER 2 N   1 ? 
ATOM   2386 C CA  . SER B 1 80  ? -17.887 -1.032  -26.725 0.670 24.030  0 82  SER 2 CA  1 ? 
ATOM   2387 C C   . SER B 1 80  ? -19.113 -0.122  -26.561 0.670 23.100  0 82  SER 2 C   1 ? 
ATOM   2388 O O   . SER B 1 80  ? -19.870 -0.369  -25.611 0.670 22.690  0 82  SER 2 O   1 ? 
ATOM   2389 C CB  . SER B 1 80  ? -16.919 -0.792  -25.592 0.670 23.230  0 82  SER 2 CB  1 ? 
ATOM   2390 O OG  . SER B 1 80  ? -15.857 -1.703  -25.701 0.670 28.190  0 82  SER 2 OG  1 ? 
ATOM   2391 N N   . PHE B 1 81  ? -19.278 0.910   -27.393 0.670 23.470  0 83  PHE 2 N   1 ? 
ATOM   2392 C CA  . PHE B 1 81  ? -20.324 1.943   -27.216 0.670 24.530  0 83  PHE 2 CA  1 ? 
ATOM   2393 C C   . PHE B 1 81  ? -21.476 1.641   -28.163 0.670 29.450  0 83  PHE 2 C   1 ? 
ATOM   2394 O O   . PHE B 1 81  ? -21.252 1.102   -29.234 0.670 30.150  0 83  PHE 2 O   1 ? 
ATOM   2395 C CB  . PHE B 1 81  ? -19.739 3.343   -27.392 0.670 23.750  0 83  PHE 2 CB  1 ? 
ATOM   2396 C CG  . PHE B 1 81  ? -18.820 3.706   -26.259 0.670 22.250  0 83  PHE 2 CG  1 ? 
ATOM   2397 C CD1 . PHE B 1 81  ? -19.336 4.157   -25.060 0.670 22.190  0 83  PHE 2 CD1 1 ? 
ATOM   2398 C CD2 . PHE B 1 81  ? -17.462 3.462   -26.349 0.670 23.840  0 83  PHE 2 CD2 1 ? 
ATOM   2399 C CE1 . PHE B 1 81  ? -18.498 4.420   -23.990 0.670 22.770  0 83  PHE 2 CE1 1 ? 
ATOM   2400 C CE2 . PHE B 1 81  ? -16.616 3.734   -25.283 0.670 21.720  0 83  PHE 2 CE2 1 ? 
ATOM   2401 C CZ  . PHE B 1 81  ? -17.140 4.213   -24.104 0.670 25.400  0 83  PHE 2 CZ  1 ? 
ATOM   2402 N N   . PRO B 1 82  ? -22.735 1.976   -27.811 0.670 33.220  0 84  PRO 2 N   1 ? 
ATOM   2403 C CA  . PRO B 1 82  ? -23.036 2.867   -26.683 0.670 35.220  0 84  PRO 2 CA  1 ? 
ATOM   2404 C C   . PRO B 1 82  ? -23.076 2.382   -25.219 0.670 31.170  0 84  PRO 2 C   1 ? 
ATOM   2405 O O   . PRO B 1 82  ? -23.111 3.256   -24.360 0.670 32.810  0 84  PRO 2 O   1 ? 
ATOM   2406 C CB  . PRO B 1 82  ? -24.463 3.347   -27.042 0.670 38.120  0 84  PRO 2 CB  1 ? 
ATOM   2407 C CG  . PRO B 1 82  ? -25.076 2.195   -27.806 0.670 37.590  0 84  PRO 2 CG  1 ? 
ATOM   2408 C CD  . PRO B 1 82  ? -23.930 1.594   -28.590 0.670 36.840  0 84  PRO 2 CD  1 ? 
ATOM   2409 N N   . LYS B 1 83  ? -23.068 1.079   -24.935 0.670 28.370  0 85  LYS 2 N   1 ? 
ATOM   2410 C CA  . LYS B 1 83  ? -23.230 0.565   -23.542 0.670 30.810  0 85  LYS 2 CA  1 ? 
ATOM   2411 C C   . LYS B 1 83  ? -22.003 0.910   -22.687 0.670 28.300  0 85  LYS 2 C   1 ? 
ATOM   2412 O O   . LYS B 1 83  ? -22.193 1.271   -21.519 0.670 30.020  0 85  LYS 2 O   1 ? 
ATOM   2413 C CB  . LYS B 1 83  ? -23.545 -0.936  -23.484 0.670 35.700  0 85  LYS 2 CB  1 ? 
ATOM   2414 C CG  . LYS B 1 83  ? -24.949 -1.232  -22.972 0.670 44.970  0 85  LYS 2 CG  1 ? 
ATOM   2415 C CD  . LYS B 1 83  ? -25.359 -2.686  -22.930 0.670 50.640  0 85  LYS 2 CD  1 ? 
ATOM   2416 C CE  . LYS B 1 83  ? -26.861 -2.844  -22.764 0.670 54.590  0 85  LYS 2 CE  1 ? 
ATOM   2417 N NZ  . LYS B 1 83  ? -27.289 -4.261  -22.895 0.670 52.700  0 85  LYS 2 NZ  1 ? 
ATOM   2418 N N   . GLY B 1 84  ? -20.802 0.832   -23.250 0.670 24.840  0 86  GLY 2 N   1 ? 
ATOM   2419 C CA  . GLY B 1 84  ? -19.553 1.245   -22.590 0.670 21.660  0 86  GLY 2 CA  1 ? 
ATOM   2420 C C   . GLY B 1 84  ? -18.703 0.094   -22.080 0.670 21.710  0 86  GLY 2 C   1 ? 
ATOM   2421 O O   . GLY B 1 84  ? -18.890 -1.087  -22.477 0.670 18.900  0 86  GLY 2 O   1 ? 
ATOM   2422 N N   . TYR B 1 85  ? -17.752 0.433   -21.220 0.670 20.120  0 87  TYR 2 N   1 ? 
ATOM   2423 C CA  . TYR B 1 85  ? -16.687 -0.486  -20.750 0.670 18.660  0 87  TYR 2 CA  1 ? 
ATOM   2424 C C   . TYR B 1 85  ? -16.159 0.026   -19.422 0.670 18.820  0 87  TYR 2 C   1 ? 
ATOM   2425 O O   . TYR B 1 85  ? -16.501 1.146   -19.000 0.670 19.520  0 87  TYR 2 O   1 ? 
ATOM   2426 C CB  . TYR B 1 85  ? -15.576 -0.675  -21.789 0.670 16.660  0 87  TYR 2 CB  1 ? 
ATOM   2427 C CG  . TYR B 1 85  ? -14.553 0.427   -21.920 0.670 17.960  0 87  TYR 2 CG  1 ? 
ATOM   2428 C CD1 . TYR B 1 85  ? -14.829 1.591   -22.624 0.670 18.280  0 87  TYR 2 CD1 1 ? 
ATOM   2429 C CD2 . TYR B 1 85  ? -13.277 0.291   -21.388 0.670 17.430  0 87  TYR 2 CD2 1 ? 
ATOM   2430 C CE1 . TYR B 1 85  ? -13.880 2.602   -22.755 0.670 19.580  0 87  TYR 2 CE1 1 ? 
ATOM   2431 C CE2 . TYR B 1 85  ? -12.315 1.288   -21.517 0.670 16.850  0 87  TYR 2 CE2 1 ? 
ATOM   2432 C CZ  . TYR B 1 85  ? -12.616 2.452   -22.203 0.670 19.170  0 87  TYR 2 CZ  1 ? 
ATOM   2433 O OH  . TYR B 1 85  ? -11.694 3.456   -22.299 0.670 17.250  0 87  TYR 2 OH  1 ? 
ATOM   2434 N N   . SER B 1 86  ? -15.361 -0.806  -18.782 0.670 18.680  0 88  SER 2 N   1 ? 
ATOM   2435 C CA  . SER B 1 86  ? -14.718 -0.517  -17.482 0.670 21.710  0 88  SER 2 CA  1 ? 
ATOM   2436 C C   . SER B 1 86  ? -13.272 -0.971  -17.572 0.670 20.370  0 88  SER 2 C   1 ? 
ATOM   2437 O O   . SER B 1 86  ? -12.971 -1.871  -18.370 0.670 20.430  0 88  SER 2 O   1 ? 
ATOM   2438 C CB  . SER B 1 86  ? -15.417 -1.208  -16.351 0.670 23.330  0 88  SER 2 CB  1 ? 
ATOM   2439 O OG  . SER B 1 86  ? -16.588 -0.498  -16.009 0.670 31.480  0 88  SER 2 OG  1 ? 
ATOM   2440 N N   . TRP B 1 87  ? -12.401 -0.297  -16.846 0.670 18.480  0 89  TRP 2 N   1 ? 
ATOM   2441 C CA  . TRP B 1 87  ? -11.023 -0.777  -16.684 0.670 18.270  0 89  TRP 2 CA  1 ? 
ATOM   2442 C C   . TRP B 1 87  ? -10.704 -0.820  -15.201 0.670 18.730  0 89  TRP 2 C   1 ? 
ATOM   2443 O O   . TRP B 1 87  ? -11.377 -0.094  -14.383 0.670 17.470  0 89  TRP 2 O   1 ? 
ATOM   2444 C CB  . TRP B 1 87  ? -10.050 0.033   -17.524 0.670 18.260  0 89  TRP 2 CB  1 ? 
ATOM   2445 C CG  . TRP B 1 87  ? -10.027 1.520   -17.318 0.670 17.900  0 89  TRP 2 CG  1 ? 
ATOM   2446 C CD1 . TRP B 1 87  ? -10.494 2.460   -18.181 0.670 16.760  0 89  TRP 2 CD1 1 ? 
ATOM   2447 C CD2 . TRP B 1 87  ? -9.327  2.242   -16.284 0.670 17.870  0 89  TRP 2 CD2 1 ? 
ATOM   2448 N NE1 . TRP B 1 87  ? -10.195 3.713   -17.729 0.670 18.140  0 89  TRP 2 NE1 1 ? 
ATOM   2449 C CE2 . TRP B 1 87  ? -9.491  3.616   -16.556 0.670 17.700  0 89  TRP 2 CE2 1 ? 
ATOM   2450 C CE3 . TRP B 1 87  ? -8.647  1.864   -15.122 0.670 18.070  0 89  TRP 2 CE3 1 ? 
ATOM   2451 C CZ2 . TRP B 1 87  ? -8.995  4.614   -15.719 0.670 17.680  0 89  TRP 2 CZ2 1 ? 
ATOM   2452 C CZ3 . TRP B 1 87  ? -8.164  2.849   -14.286 0.670 18.730  0 89  TRP 2 CZ3 1 ? 
ATOM   2453 C CH2 . TRP B 1 87  ? -8.344  4.209   -14.576 0.670 18.070  0 89  TRP 2 CH2 1 ? 
ATOM   2454 N N   . GLU B 1 88  ? -9.733  -1.663  -14.875 0.670 20.410  0 90  GLU 2 N   1 ? 
ATOM   2455 C CA  . GLU B 1 88  ? -9.126  -1.774  -13.529 0.670 20.820  0 90  GLU 2 CA  1 ? 
ATOM   2456 C C   . GLU B 1 88  ? -7.619  -1.719  -13.698 0.670 19.270  0 90  GLU 2 C   1 ? 
ATOM   2457 O O   . GLU B 1 88  ? -7.104  -2.381  -14.616 0.670 19.590  0 90  GLU 2 O   1 ? 
ATOM   2458 C CB  . GLU B 1 88  ? -9.468  -3.126  -12.903 0.670 25.670  0 90  GLU 2 CB  1 ? 
ATOM   2459 C CG  . GLU B 1 88  ? -10.903 -3.256  -12.490 0.670 33.280  0 90  GLU 2 CG  1 ? 
ATOM   2460 C CD  . GLU B 1 88  ? -11.089 -4.463  -11.590 0.670 41.870  0 90  GLU 2 CD  1 ? 
ATOM   2461 O OE1 . GLU B 1 88  ? -11.228 -5.600  -12.145 0.670 43.570  0 90  GLU 2 OE1 1 ? 
ATOM   2462 O OE2 . GLU B 1 88  ? -11.032 -4.269  -10.343 0.670 44.100  0 90  GLU 2 OE2 1 ? 
ATOM   2463 N N   . ARG B 1 89  ? -6.917  -0.929  -12.903 0.670 18.800  0 91  ARG 2 N   1 ? 
ATOM   2464 C CA  . ARG B 1 89  ? -5.475  -0.698  -13.158 0.670 17.230  0 91  ARG 2 CA  1 ? 
ATOM   2465 C C   . ARG B 1 89  ? -4.682  -0.811  -11.860 0.670 18.650  0 91  ARG 2 C   1 ? 
ATOM   2466 O O   . ARG B 1 89  ? -5.163  -0.289  -10.842 0.670 18.170  0 91  ARG 2 O   1 ? 
ATOM   2467 C CB  . ARG B 1 89  ? -5.252  0.690   -13.744 0.670 17.930  0 91  ARG 2 CB  1 ? 
ATOM   2468 C CG  . ARG B 1 89  ? -3.807  0.997   -14.077 0.670 19.480  0 91  ARG 2 CG  1 ? 
ATOM   2469 C CD  . ARG B 1 89  ? -3.638  2.283   -14.891 0.670 21.110  0 91  ARG 2 CD  1 ? 
ATOM   2470 N NE  . ARG B 1 89  ? -4.447  2.233   -16.101 0.670 20.340  0 91  ARG 2 NE  1 ? 
ATOM   2471 C CZ  . ARG B 1 89  ? -5.058  3.269   -16.680 0.670 22.210  0 91  ARG 2 CZ  1 ? 
ATOM   2472 N NH1 . ARG B 1 89  ? -4.853  4.513   -16.269 0.670 22.510  0 91  ARG 2 NH1 1 ? 
ATOM   2473 N NH2 . ARG B 1 89  ? -5.833  3.051   -17.719 0.670 19.600  0 91  ARG 2 NH2 1 ? 
ATOM   2474 N N   . SER B 1 90  ? -3.519  -1.465  -11.909 0.670 19.280  0 92  SER 2 N   1 ? 
ATOM   2475 C CA  . SER B 1 90  ? -2.523  -1.450  -10.810 0.670 19.480  0 92  SER 2 CA  1 ? 
ATOM   2476 C C   . SER B 1 90  ? -1.353  -0.556  -11.241 0.670 18.450  0 92  SER 2 C   1 ? 
ATOM   2477 O O   . SER B 1 90  ? -0.905  -0.660  -12.391 0.670 17.650  0 92  SER 2 O   1 ? 
ATOM   2478 C CB  . SER B 1 90  ? -2.061  -2.827  -10.480 0.670 20.540  0 92  SER 2 CB  1 ? 
ATOM   2479 O OG  . SER B 1 90  ? -1.554  -3.398  -11.666 0.670 23.500  0 92  SER 2 OG  1 ? 
ATOM   2480 N N   . LEU B 1 91  ? -0.908  0.310   -10.347 0.670 18.430  0 93  LEU 2 N   1 ? 
ATOM   2481 C CA  . LEU B 1 91  ? 0.335   1.114   -10.466 0.670 19.890  0 93  LEU 2 CA  1 ? 
ATOM   2482 C C   . LEU B 1 91  ? 1.267   0.669   -9.352  0.670 19.830  0 93  LEU 2 C   1 ? 
ATOM   2483 O O   . LEU B 1 91  ? 0.898   0.884   -8.191  0.670 22.650  0 93  LEU 2 O   1 ? 
ATOM   2484 C CB  . LEU B 1 91  ? 0.033   2.601   -10.314 0.670 21.030  0 93  LEU 2 CB  1 ? 
ATOM   2485 C CG  . LEU B 1 91  ? -0.754  3.253   -11.447 0.670 25.250  0 93  LEU 2 CG  1 ? 
ATOM   2486 C CD1 . LEU B 1 91  ? -2.244  3.002   -11.280 0.670 27.700  0 93  LEU 2 CD1 1 ? 
ATOM   2487 C CD2 . LEU B 1 91  ? -0.487  4.741   -11.465 0.670 25.840  0 93  LEU 2 CD2 1 ? 
ATOM   2488 N N   . THR B 1 92  ? 2.375   0.028   -9.706  0.670 19.390  0 94  THR 2 N   1 ? 
ATOM   2489 C CA  . THR B 1 92  ? 3.414   -0.436  -8.766  0.670 21.260  0 94  THR 2 CA  1 ? 
ATOM   2490 C C   . THR B 1 92  ? 4.642   0.448   -8.929  0.670 19.440  0 94  THR 2 C   1 ? 
ATOM   2491 O O   . THR B 1 92  ? 5.223   0.404   -9.985  0.670 19.250  0 94  THR 2 O   1 ? 
ATOM   2492 C CB  . THR B 1 92  ? 3.708   -1.920  -9.012  0.670 22.960  0 94  THR 2 CB  1 ? 
ATOM   2493 O OG1 . THR B 1 92  ? 2.437   -2.572  -9.030  0.670 23.180  0 94  THR 2 OG1 1 ? 
ATOM   2494 C CG2 . THR B 1 92  ? 4.569   -2.521  -7.933  0.670 25.860  0 94  THR 2 CG2 1 ? 
ATOM   2495 N N   . PHE B 1 93  ? 5.021   1.186   -7.885  0.670 21.090  0 95  PHE 2 N   1 ? 
ATOM   2496 C CA  . PHE B 1 93  ? 6.169   2.127   -7.897  0.670 21.580  0 95  PHE 2 CA  1 ? 
ATOM   2497 C C   . PHE B 1 93  ? 7.377   1.418   -7.282  0.670 23.340  0 95  PHE 2 C   1 ? 
ATOM   2498 O O   . PHE B 1 93  ? 7.192   0.447   -6.532  0.670 21.680  0 95  PHE 2 O   1 ? 
ATOM   2499 C CB  . PHE B 1 93  ? 5.794   3.421   -7.187  0.670 22.060  0 95  PHE 2 CB  1 ? 
ATOM   2500 C CG  . PHE B 1 93  ? 4.767   4.252   -7.908  0.670 20.910  0 95  PHE 2 CG  1 ? 
ATOM   2501 C CD1 . PHE B 1 93  ? 5.154   5.205   -8.833  0.670 21.790  0 95  PHE 2 CD1 1 ? 
ATOM   2502 C CD2 . PHE B 1 93  ? 3.421   4.119   -7.625  0.670 22.190  0 95  PHE 2 CD2 1 ? 
ATOM   2503 C CE1 . PHE B 1 93  ? 4.213   6.000   -9.465  0.670 20.470  0 95  PHE 2 CE1 1 ? 
ATOM   2504 C CE2 . PHE B 1 93  ? 2.481   4.916   -8.262  0.670 23.050  0 95  PHE 2 CE2 1 ? 
ATOM   2505 C CZ  . PHE B 1 93  ? 2.887   5.864   -9.172  0.670 23.170  0 95  PHE 2 CZ  1 ? 
ATOM   2506 N N   . GLU B 1 94  ? 8.580   1.860   -7.629  0.670 24.020  0 96  GLU 2 N   1 ? 
ATOM   2507 C CA  . GLU B 1 94  ? 9.821   1.118   -7.275  0.670 26.630  0 96  GLU 2 CA  1 ? 
ATOM   2508 C C   . GLU B 1 94  ? 10.111  1.167   -5.763  0.670 25.350  0 96  GLU 2 C   1 ? 
ATOM   2509 O O   . GLU B 1 94  ? 10.873  0.294   -5.320  0.670 29.610  0 96  GLU 2 O   1 ? 
ATOM   2510 C CB  . GLU B 1 94  ? 11.002  1.628   -8.103  0.670 27.400  0 96  GLU 2 CB  1 ? 
ATOM   2511 C CG  . GLU B 1 94  ? 11.202  3.127   -8.058  0.670 29.560  0 96  GLU 2 CG  1 ? 
ATOM   2512 C CD  . GLU B 1 94  ? 12.544  3.546   -8.636  0.670 29.120  0 96  GLU 2 CD  1 ? 
ATOM   2513 O OE1 . GLU B 1 94  ? 13.569  3.150   -8.065  0.670 34.980  0 96  GLU 2 OE1 1 ? 
ATOM   2514 O OE2 . GLU B 1 94  ? 12.565  4.240   -9.657  0.670 25.770  0 96  GLU 2 OE2 1 ? 
ATOM   2515 N N   . ASP B 1 95  ? 9.546   2.121   -5.007  0.670 25.980  0 97  ASP 2 N   1 ? 
ATOM   2516 C CA  . ASP B 1 95  ? 9.755   2.258   -3.537  0.670 23.620  0 97  ASP 2 CA  1 ? 
ATOM   2517 C C   . ASP B 1 95  ? 8.605   1.612   -2.736  0.670 24.770  0 97  ASP 2 C   1 ? 
ATOM   2518 O O   . ASP B 1 95  ? 8.497   1.895   -1.515  0.670 25.360  0 97  ASP 2 O   1 ? 
ATOM   2519 C CB  . ASP B 1 95  ? 9.959   3.723   -3.143  0.670 23.850  0 97  ASP 2 CB  1 ? 
ATOM   2520 C CG  . ASP B 1 95  ? 8.790   4.678   -3.362  0.670 22.570  0 97  ASP 2 CG  1 ? 
ATOM   2521 O OD1 . ASP B 1 95  ? 7.744   4.263   -3.910  0.670 22.800  0 97  ASP 2 OD1 1 ? 
ATOM   2522 O OD2 . ASP B 1 95  ? 8.927   5.841   -2.949  0.670 23.290  0 97  ASP 2 OD2 1 ? 
ATOM   2523 N N   . GLY B 1 96  ? 7.746   0.804   -3.371  0.670 23.420  0 98  GLY 2 N   1 ? 
ATOM   2524 C CA  . GLY B 1 96  ? 6.692   0.052   -2.662  0.670 24.190  0 98  GLY 2 CA  1 ? 
ATOM   2525 C C   . GLY B 1 96  ? 5.327   0.730   -2.663  0.670 23.010  0 98  GLY 2 C   1 ? 
ATOM   2526 O O   . GLY B 1 96  ? 4.366   0.126   -2.151  0.670 22.930  0 98  GLY 2 O   1 ? 
ATOM   2527 N N   . GLY B 1 97  ? 5.223   1.947   -3.189  0.670 21.270  0 99  GLY 2 N   1 ? 
ATOM   2528 C CA  . GLY B 1 97  ? 3.926   2.649   -3.294  0.670 19.650  0 99  GLY 2 CA  1 ? 
ATOM   2529 C C   . GLY B 1 97  ? 3.047   1.846   -4.236  0.670 20.390  0 99  GLY 2 C   1 ? 
ATOM   2530 O O   . GLY B 1 97  ? 3.584   1.355   -5.249  0.670 19.370  0 99  GLY 2 O   1 ? 
ATOM   2531 N N   . ILE B 1 98  ? 1.777   1.629   -3.895  0.670 19.860  0 100 ILE 2 N   1 ? 
ATOM   2532 C CA  . ILE B 1 98  ? 0.866   0.876   -4.794  0.670 22.540  0 100 ILE 2 CA  1 ? 
ATOM   2533 C C   . ILE B 1 98  ? -0.418  1.689   -4.953  0.670 20.850  0 100 ILE 2 C   1 ? 
ATOM   2534 O O   . ILE B 1 98  ? -0.954  2.186   -3.938  0.670 18.920  0 100 ILE 2 O   1 ? 
ATOM   2535 C CB  . ILE B 1 98  ? 0.617   -0.564  -4.299  0.670 25.990  0 100 ILE 2 CB  1 ? 
ATOM   2536 C CG1 . ILE B 1 98  ? -0.326  -1.328  -5.229  0.670 33.280  0 100 ILE 2 CG1 1 ? 
ATOM   2537 C CG2 . ILE B 1 98  ? 0.130   -0.588  -2.876  0.670 28.810  0 100 ILE 2 CG2 1 ? 
ATOM   2538 C CD1 . ILE B 1 98  ? 0.381   -2.001  -6.380  0.670 39.010  0 100 ILE 2 CD1 1 ? 
ATOM   2539 N N   . CYS B 1 99  ? -0.900  1.806   -6.184  0.670 17.780  0 101 CYS 2 N   1 ? 
ATOM   2540 C CA  . CYS B 1 99  ? -2.237  2.381   -6.481  0.670 16.700  0 101 CYS 2 CA  1 ? 
ATOM   2541 C C   . CYS B 1 99  ? -3.119  1.363   -7.185  0.670 17.270  0 101 CYS 2 C   1 ? 
ATOM   2542 O O   . CYS B 1 99  ? -2.615  0.619   -8.036  0.670 20.150  0 101 CYS 2 O   1 ? 
ATOM   2543 C CB  . CYS B 1 99  ? -2.096  3.613   -7.338  0.670 17.080  0 101 CYS 2 CB  1 ? 
ATOM   2544 S SG  . CYS B 1 99  ? -1.143  4.839   -6.444  0.670 16.140  0 101 CYS 2 SG  1 ? 
ATOM   2545 N N   . ASN B 1 100 ? -4.384  1.332   -6.810  0.670 18.370  0 102 ASN 2 N   1 ? 
ATOM   2546 C CA  . ASN B 1 100 ? -5.463  0.631   -7.545  0.670 20.590  0 102 ASN 2 CA  1 ? 
ATOM   2547 C C   . ASN B 1 100 ? -6.455  1.694   -8.007  0.670 18.570  0 102 ASN 2 C   1 ? 
ATOM   2548 O O   . ASN B 1 100 ? -6.810  2.569   -7.218  0.670 17.190  0 102 ASN 2 O   1 ? 
ATOM   2549 C CB  . ASN B 1 100 ? -6.126  -0.427  -6.673  0.670 25.260  0 102 ASN 2 CB  1 ? 
ATOM   2550 C CG  . ASN B 1 100 ? -5.105  -1.450  -6.230  0.670 31.260  0 102 ASN 2 CG  1 ? 
ATOM   2551 O OD1 . ASN B 1 100 ? -4.456  -2.082  -7.073  0.670 37.960  0 102 ASN 2 OD1 1 ? 
ATOM   2552 N ND2 . ASN B 1 100 ? -4.944  -1.597  -4.924  0.670 36.650  0 102 ASN 2 ND2 1 ? 
ATOM   2553 N N   . ALA B 1 101 ? -6.805  1.667   -9.277  0.670 17.730  0 103 ALA 2 N   1 ? 
ATOM   2554 C CA  . ALA B 1 101 ? -7.769  2.599   -9.898  0.670 18.160  0 103 ALA 2 CA  1 ? 
ATOM   2555 C C   . ALA B 1 101 ? -8.779  1.810   -10.743 0.670 20.030  0 103 ALA 2 C   1 ? 
ATOM   2556 O O   . ALA B 1 101 ? -8.468  0.722   -11.298 0.670 20.320  0 103 ALA 2 O   1 ? 
ATOM   2557 C CB  . ALA B 1 101 ? -7.035  3.635   -10.692 0.670 18.450  0 103 ALA 2 CB  1 ? 
ATOM   2558 N N   . ARG B 1 102 ? -9.978  2.337   -10.851 0.670 20.040  0 104 ARG 2 N   1 ? 
ATOM   2559 C CA  . ARG B 1 102 ? -10.943 1.808   -11.831 0.670 22.100  0 104 ARG 2 CA  1 ? 
ATOM   2560 C C   . ARG B 1 102 ? -11.783 2.968   -12.378 0.670 19.810  0 104 ARG 2 C   1 ? 
ATOM   2561 O O   . ARG B 1 102 ? -11.912 4.023   -11.727 0.670 18.250  0 104 ARG 2 O   1 ? 
ATOM   2562 C CB  . ARG B 1 102 ? -11.743 0.649   -11.228 0.670 26.440  0 104 ARG 2 CB  1 ? 
ATOM   2563 C CG  . ARG B 1 102 ? -12.678 1.009   -10.094 0.670 32.540  0 104 ARG 2 CG  1 ? 
ATOM   2564 C CD  . ARG B 1 102 ? -13.148 -0.251  -9.370  0.670 42.370  0 104 ARG 2 CD  1 ? 
ATOM   2565 N NE  . ARG B 1 102 ? -12.431 -0.476  -8.109  0.670 49.490  0 104 ARG 2 NE  1 ? 
ATOM   2566 C CZ  . ARG B 1 102 ? -12.867 -0.128  -6.890  0.670 59.210  0 104 ARG 2 CZ  1 ? 
ATOM   2567 N NH1 . ARG B 1 102 ? -12.123 -0.385  -5.829  0.670 62.850  0 104 ARG 2 NH1 1 ? 
ATOM   2568 N NH2 . ARG B 1 102 ? -14.035 0.479   -6.722  0.670 66.250  0 104 ARG 2 NH2 1 ? 
ATOM   2569 N N   . ASN B 1 103 ? -12.307 2.770   -13.569 0.670 17.870  0 105 ASN 2 N   1 ? 
ATOM   2570 C CA  . ASN B 1 103 ? -13.218 3.711   -14.263 0.670 18.090  0 105 ASN 2 CA  1 ? 
ATOM   2571 C C   . ASN B 1 103 ? -14.349 2.889   -14.868 0.670 18.980  0 105 ASN 2 C   1 ? 
ATOM   2572 O O   . ASN B 1 103 ? -14.051 1.860   -15.496 0.670 19.590  0 105 ASN 2 O   1 ? 
ATOM   2573 C CB  . ASN B 1 103 ? -12.480 4.513   -15.325 0.670 17.790  0 105 ASN 2 CB  1 ? 
ATOM   2574 C CG  . ASN B 1 103 ? -13.271 5.697   -15.824 0.670 18.900  0 105 ASN 2 CG  1 ? 
ATOM   2575 O OD1 . ASN B 1 103 ? -14.418 5.890   -15.403 0.670 20.000  0 105 ASN 2 OD1 1 ? 
ATOM   2576 N ND2 . ASN B 1 103 ? -12.684 6.476   -16.731 0.670 19.860  0 105 ASN 2 ND2 1 ? 
ATOM   2577 N N   . ASP B 1 104 ? -15.583 3.321   -14.643 0.670 19.710  0 106 ASP 2 N   1 ? 
ATOM   2578 C CA  . ASP B 1 104 ? -16.794 2.808   -15.320 0.670 22.390  0 106 ASP 2 CA  1 ? 
ATOM   2579 C C   . ASP B 1 104 ? -17.222 3.906   -16.291 0.670 20.980  0 106 ASP 2 C   1 ? 
ATOM   2580 O O   . ASP B 1 104 ? -17.505 5.015   -15.812 0.670 19.850  0 106 ASP 2 O   1 ? 
ATOM   2581 C CB  . ASP B 1 104 ? -17.869 2.452   -14.289 0.670 26.040  0 106 ASP 2 CB  1 ? 
ATOM   2582 C CG  . ASP B 1 104 ? -17.465 1.271   -13.414 0.670 31.180  0 106 ASP 2 CG  1 ? 
ATOM   2583 O OD1 . ASP B 1 104 ? -17.327 0.160   -13.956 0.670 34.420  0 106 ASP 2 OD1 1 ? 
ATOM   2584 O OD2 . ASP B 1 104 ? -17.257 1.473   -12.190 0.670 40.180  0 106 ASP 2 OD2 1 ? 
ATOM   2585 N N   . ILE B 1 105 ? -17.191 3.625   -17.592 0.670 18.750  0 107 ILE 2 N   1 ? 
ATOM   2586 C CA  . ILE B 1 105 ? -17.447 4.638   -18.647 0.670 18.980  0 107 ILE 2 CA  1 ? 
ATOM   2587 C C   . ILE B 1 105 ? -18.773 4.323   -19.343 0.670 19.500  0 107 ILE 2 C   1 ? 
ATOM   2588 O O   . ILE B 1 105 ? -18.963 3.169   -19.781 0.670 19.880  0 107 ILE 2 O   1 ? 
ATOM   2589 C CB  . ILE B 1 105 ? -16.274 4.739   -19.619 0.670 18.600  0 107 ILE 2 CB  1 ? 
ATOM   2590 C CG1 . ILE B 1 105 ? -14.955 4.911   -18.864 0.670 19.660  0 107 ILE 2 CG1 1 ? 
ATOM   2591 C CG2 . ILE B 1 105 ? -16.515 5.873   -20.611 0.670 18.930  0 107 ILE 2 CG2 1 ? 
ATOM   2592 C CD1 . ILE B 1 105 ? -13.758 4.574   -19.662 0.670 20.480  0 107 ILE 2 CD1 1 ? 
ATOM   2593 N N   . THR B 1 106 ? -19.669 5.299   -19.380 0.670 19.130  0 108 THR 2 N   1 ? 
ATOM   2594 C CA  . THR B 1 106 ? -20.965 5.247   -20.106 0.670 20.490  0 108 THR 2 CA  1 ? 
ATOM   2595 C C   . THR B 1 106 ? -21.005 6.424   -21.090 0.670 22.690  0 108 THR 2 C   1 ? 
ATOM   2596 O O   . THR B 1 106 ? -20.127 7.302   -21.051 0.670 19.230  0 108 THR 2 O   1 ? 
ATOM   2597 C CB  . THR B 1 106 ? -22.176 5.269   -19.163 0.670 22.100  0 108 THR 2 CB  1 ? 
ATOM   2598 O OG1 . THR B 1 106 ? -22.147 6.492   -18.422 0.670 23.670  0 108 THR 2 OG1 1 ? 
ATOM   2599 C CG2 . THR B 1 106 ? -22.213 4.103   -18.188 0.670 23.710  0 108 THR 2 CG2 1 ? 
ATOM   2600 N N   . MET B 1 107 ? -21.991 6.412   -21.965 0.670 21.970  0 109 MET 2 N   1 ? 
ATOM   2601 C CA  . MET B 1 107 ? -22.162 7.443   -23.001 0.670 24.940  0 109 MET 2 CA  1 ? 
ATOM   2602 C C   . MET B 1 107 ? -23.644 7.806   -22.971 0.670 24.870  0 109 MET 2 C   1 ? 
ATOM   2603 O O   . MET B 1 107 ? -24.454 6.886   -23.054 0.670 25.020  0 109 MET 2 O   1 ? 
ATOM   2604 C CB  . MET B 1 107 ? -21.759 6.884   -24.375 0.670 26.180  0 109 MET 2 CB  1 ? 
ATOM   2605 C CG  . MET B 1 107 ? -21.506 7.936   -25.425 0.670 28.580  0 109 MET 2 CG  1 ? 
ATOM   2606 S SD  . MET B 1 107 ? -21.394 7.245   -27.105 0.670 31.900  0 109 MET 2 SD  1 ? 
ATOM   2607 C CE  . MET B 1 107 ? -23.122 6.876   -27.370 0.670 32.050  0 109 MET 2 CE  1 ? 
ATOM   2608 N N   . GLU B 1 108 ? -23.966 9.080   -22.759 0.670 24.350  0 110 GLU 2 N   1 ? 
ATOM   2609 C CA  . GLU B 1 108 ? -25.333 9.622   -22.962 0.670 24.440  0 110 GLU 2 CA  1 ? 
ATOM   2610 C C   . GLU B 1 108 ? -25.218 10.695  -24.043 0.670 24.130  0 110 GLU 2 C   1 ? 
ATOM   2611 O O   . GLU B 1 108 ? -24.594 11.726  -23.799 0.670 23.300  0 110 GLU 2 O   1 ? 
ATOM   2612 C CB  . GLU B 1 108 ? -25.914 10.176  -21.653 0.670 26.940  0 110 GLU 2 CB  1 ? 
ATOM   2613 C CG  . GLU B 1 108 ? -25.863 9.222   -20.472 0.670 26.260  0 110 GLU 2 CG  1 ? 
ATOM   2614 C CD  . GLU B 1 108 ? -26.768 7.996   -20.535 0.670 30.080  0 110 GLU 2 CD  1 ? 
ATOM   2615 O OE1 . GLU B 1 108 ? -27.664 7.955   -21.405 0.670 33.640  0 110 GLU 2 OE1 1 ? 
ATOM   2616 O OE2 . GLU B 1 108 ? -26.546 7.061   -19.739 0.670 29.230  0 110 GLU 2 OE2 1 ? 
ATOM   2617 N N   . GLY B 1 109 ? -25.803 10.453  -25.208 0.670 25.230  0 111 GLY 2 N   1 ? 
ATOM   2618 C CA  . GLY B 1 109 ? -25.736 11.393  -26.339 0.670 26.400  0 111 GLY 2 CA  1 ? 
ATOM   2619 C C   . GLY B 1 109 ? -24.294 11.636  -26.750 0.670 26.630  0 111 GLY 2 C   1 ? 
ATOM   2620 O O   . GLY B 1 109 ? -23.607 10.681  -27.092 0.670 29.390  0 111 GLY 2 O   1 ? 
ATOM   2621 N N   . ASP B 1 110 ? -23.833 12.874  -26.663 0.670 26.520  0 112 ASP 2 N   1 ? 
ATOM   2622 C CA  . ASP B 1 110 ? -22.484 13.258  -27.129 0.670 28.560  0 112 ASP 2 CA  1 ? 
ATOM   2623 C C   . ASP B 1 110 ? -21.496 13.256  -25.950 0.670 22.820  0 112 ASP 2 C   1 ? 
ATOM   2624 O O   . ASP B 1 110 ? -20.394 13.704  -26.175 0.670 22.400  0 112 ASP 2 O   1 ? 
ATOM   2625 C CB  . ASP B 1 110 ? -22.564 14.622  -27.814 0.670 32.040  0 112 ASP 2 CB  1 ? 
ATOM   2626 C CG  . ASP B 1 110 ? -23.053 15.724  -26.905 0.670 35.130  0 112 ASP 2 CG  1 ? 
ATOM   2627 O OD1 . ASP B 1 110 ? -23.563 15.411  -25.799 0.670 37.410  0 112 ASP 2 OD1 1 ? 
ATOM   2628 O OD2 . ASP B 1 110 ? -22.893 16.896  -27.294 0.670 44.010  0 112 ASP 2 OD2 1 ? 
ATOM   2629 N N   . THR B 1 111 ? -21.867 12.771  -24.754 0.670 21.220  0 113 THR 2 N   1 ? 
ATOM   2630 C CA  . THR B 1 111 ? -21.022 12.879  -23.527 0.670 19.610  0 113 THR 2 CA  1 ? 
ATOM   2631 C C   . THR B 1 111 ? -20.588 11.506  -22.994 0.670 19.230  0 113 THR 2 C   1 ? 
ATOM   2632 O O   . THR B 1 111 ? -21.442 10.648  -22.763 0.670 18.990  0 113 THR 2 O   1 ? 
ATOM   2633 C CB  . THR B 1 111 ? -21.727 13.702  -22.455 0.670 20.100  0 113 THR 2 CB  1 ? 
ATOM   2634 O OG1 . THR B 1 111 ? -22.023 14.969  -23.026 0.670 19.290  0 113 THR 2 OG1 1 ? 
ATOM   2635 C CG2 . THR B 1 111 ? -20.877 13.928  -21.228 0.670 21.080  0 113 THR 2 CG2 1 ? 
ATOM   2636 N N   . PHE B 1 112 ? -19.286 11.318  -22.761 0.670 19.800  0 114 PHE 2 N   1 ? 
ATOM   2637 C CA  . PHE B 1 112 ? -18.742 10.207  -21.932 0.670 18.450  0 114 PHE 2 CA  1 ? 
ATOM   2638 C C   . PHE B 1 112 ? -18.795 10.604  -20.454 0.670 17.240  0 114 PHE 2 C   1 ? 
ATOM   2639 O O   . PHE B 1 112 ? -18.190 11.615  -20.098 0.670 18.360  0 114 PHE 2 O   1 ? 
ATOM   2640 C CB  . PHE B 1 112 ? -17.302 9.868   -22.308 0.670 18.370  0 114 PHE 2 CB  1 ? 
ATOM   2641 C CG  . PHE B 1 112 ? -17.143 9.352   -23.711 0.670 18.520  0 114 PHE 2 CG  1 ? 
ATOM   2642 C CD1 . PHE B 1 112 ? -17.618 8.104   -24.049 0.670 19.400  0 114 PHE 2 CD1 1 ? 
ATOM   2643 C CD2 . PHE B 1 112 ? -16.566 10.136  -24.693 0.670 19.170  0 114 PHE 2 CD2 1 ? 
ATOM   2644 C CE1 . PHE B 1 112 ? -17.488 7.620   -25.343 0.670 18.730  0 114 PHE 2 CE1 1 ? 
ATOM   2645 C CE2 . PHE B 1 112 ? -16.445 9.651   -25.988 0.670 20.710  0 114 PHE 2 CE2 1 ? 
ATOM   2646 C CZ  . PHE B 1 112 ? -16.880 8.385   -26.299 0.670 19.690  0 114 PHE 2 CZ  1 ? 
ATOM   2647 N N   . TYR B 1 113 ? -19.440 9.783   -19.633 0.670 17.810  0 115 TYR 2 N   1 ? 
ATOM   2648 C CA  . TYR B 1 113 ? -19.520 9.912   -18.158 0.670 18.440  0 115 TYR 2 CA  1 ? 
ATOM   2649 C C   . TYR B 1 113 ? -18.560 8.898   -17.533 0.670 17.680  0 115 TYR 2 C   1 ? 
ATOM   2650 O O   . TYR B 1 113 ? -18.479 7.758   -18.022 0.670 18.220  0 115 TYR 2 O   1 ? 
ATOM   2651 C CB  . TYR B 1 113 ? -20.961 9.720   -17.687 0.670 19.400  0 115 TYR 2 CB  1 ? 
ATOM   2652 C CG  . TYR B 1 113 ? -21.838 10.919  -17.921 0.670 19.680  0 115 TYR 2 CG  1 ? 
ATOM   2653 C CD1 . TYR B 1 113 ? -21.837 11.970  -17.022 0.670 21.220  0 115 TYR 2 CD1 1 ? 
ATOM   2654 C CD2 . TYR B 1 113 ? -22.598 11.050  -19.075 0.670 20.950  0 115 TYR 2 CD2 1 ? 
ATOM   2655 C CE1 . TYR B 1 113 ? -22.616 13.099  -17.234 0.670 20.950  0 115 TYR 2 CE1 1 ? 
ATOM   2656 C CE2 . TYR B 1 113 ? -23.366 12.183  -19.312 0.670 22.230  0 115 TYR 2 CE2 1 ? 
ATOM   2657 C CZ  . TYR B 1 113 ? -23.362 13.214  -18.389 0.670 21.510  0 115 TYR 2 CZ  1 ? 
ATOM   2658 O OH  . TYR B 1 113 ? -24.136 14.323  -18.574 0.670 24.340  0 115 TYR 2 OH  1 ? 
ATOM   2659 N N   . ASN B 1 114 ? -17.814 9.334   -16.521 0.670 17.160  0 116 ASN 2 N   1 ? 
ATOM   2660 C CA  . ASN B 1 114 ? -16.695 8.553   -15.948 0.670 16.830  0 116 ASN 2 CA  1 ? 
ATOM   2661 C C   . ASN B 1 114 ? -16.865 8.501   -14.441 0.670 16.670  0 116 ASN 2 C   1 ? 
ATOM   2662 O O   . ASN B 1 114 ? -16.813 9.554   -13.803 0.670 16.640  0 116 ASN 2 O   1 ? 
ATOM   2663 C CB  . ASN B 1 114 ? -15.342 9.168   -16.307 0.670 17.400  0 116 ASN 2 CB  1 ? 
ATOM   2664 C CG  . ASN B 1 114 ? -15.111 9.293   -17.797 0.670 17.210  0 116 ASN 2 CG  1 ? 
ATOM   2665 O OD1 . ASN B 1 114 ? -14.392 8.495   -18.363 0.670 17.710  0 116 ASN 2 OD1 1 ? 
ATOM   2666 N ND2 . ASN B 1 114 ? -15.626 10.345  -18.409 0.670 16.290  0 116 ASN 2 ND2 1 ? 
ATOM   2667 N N   . LYS B 1 115 ? -16.992 7.297   -13.901 0.670 17.560  0 117 LYS 2 N   1 ? 
ATOM   2668 C CA  . LYS B 1 115 ? -17.088 7.064   -12.450 0.670 19.520  0 117 LYS 2 CA  1 ? 
ATOM   2669 C C   . LYS B 1 115 ? -15.739 6.496   -12.021 0.670 18.170  0 117 LYS 2 C   1 ? 
ATOM   2670 O O   . LYS B 1 115 ? -15.519 5.287   -12.172 0.670 17.020  0 117 LYS 2 O   1 ? 
ATOM   2671 C CB  . LYS B 1 115 ? -18.294 6.162   -12.167 0.670 25.030  0 117 LYS 2 CB  1 ? 
ATOM   2672 C CG  . LYS B 1 115 ? -18.595 5.872   -10.711 0.670 28.790  0 117 LYS 2 CG  1 ? 
ATOM   2673 C CD  . LYS B 1 115 ? -19.670 4.822   -10.586 0.670 33.380  0 117 LYS 2 CD  1 ? 
ATOM   2674 C CE  . LYS B 1 115 ? -20.784 5.209   -9.639  0.670 40.260  0 117 LYS 2 CE  1 ? 
ATOM   2675 N NZ  . LYS B 1 115 ? -20.428 4.899   -8.226  0.670 45.880  0 117 LYS 2 NZ  1 ? 
ATOM   2676 N N   . VAL B 1 116 ? -14.849 7.358   -11.533 0.670 16.430  0 118 VAL 2 N   1 ? 
ATOM   2677 C CA  . VAL B 1 116 ? -13.443 6.975   -11.265 0.670 17.730  0 118 VAL 2 CA  1 ? 
ATOM   2678 C C   . VAL B 1 116 ? -13.260 6.783   -9.761  0.670 18.620  0 118 VAL 2 C   1 ? 
ATOM   2679 O O   . VAL B 1 116 ? -13.744 7.628   -8.974  0.670 15.400  0 118 VAL 2 O   1 ? 
ATOM   2680 C CB  . VAL B 1 116 ? -12.463 8.022   -11.828 0.670 19.150  0 118 VAL 2 CB  1 ? 
ATOM   2681 C CG1 . VAL B 1 116 ? -11.049 7.499   -11.830 0.670 21.530  0 118 VAL 2 CG1 1 ? 
ATOM   2682 C CG2 . VAL B 1 116 ? -12.862 8.454   -13.225 0.670 21.060  0 118 VAL 2 CG2 1 ? 
ATOM   2683 N N   . ARG B 1 117 ? -12.510 5.755   -9.389  0.670 18.190  0 119 ARG 2 N   1 ? 
ATOM   2684 C CA  . ARG B 1 117 ? -12.071 5.551   -7.992  0.670 21.060  0 119 ARG 2 CA  1 ? 
ATOM   2685 C C   . ARG B 1 117 ? -10.571 5.340   -8.028  0.670 19.630  0 119 ARG 2 C   1 ? 
ATOM   2686 O O   . ARG B 1 117 ? -10.073 4.661   -8.958  0.670 17.950  0 119 ARG 2 O   1 ? 
ATOM   2687 C CB  . ARG B 1 117 ? -12.822 4.387   -7.348  0.670 23.790  0 119 ARG 2 CB  1 ? 
ATOM   2688 C CG  . ARG B 1 117 ? -14.337 4.535   -7.390  0.670 28.150  0 119 ARG 2 CG  1 ? 
ATOM   2689 C CD  . ARG B 1 117 ? -14.797 5.542   -6.355  0.670 32.160  0 119 ARG 2 CD  1 ? 
ATOM   2690 N NE  . ARG B 1 117 ? -16.241 5.763   -6.344  0.670 35.030  0 119 ARG 2 NE  1 ? 
ATOM   2691 C CZ  . ARG B 1 117 ? -16.908 6.667   -7.064  0.670 36.360  0 119 ARG 2 CZ  1 ? 
ATOM   2692 N NH1 . ARG B 1 117 ? -16.299 7.477   -7.915  0.670 36.930  0 119 ARG 2 NH1 1 ? 
ATOM   2693 N NH2 . ARG B 1 117 ? -18.220 6.745   -6.932  0.670 41.820  0 119 ARG 2 NH2 1 ? 
ATOM   2694 N N   . PHE B 1 118 ? -9.859  5.927   -7.075  0.670 19.240  0 120 PHE 2 N   1 ? 
ATOM   2695 C CA  . PHE B 1 118 ? -8.381  5.856   -6.992  0.670 18.740  0 120 PHE 2 CA  1 ? 
ATOM   2696 C C   . PHE B 1 118 ? -7.986  5.627   -5.534  0.670 19.280  0 120 PHE 2 C   1 ? 
ATOM   2697 O O   . PHE B 1 118 ? -8.234  6.551   -4.730  0.670 17.880  0 120 PHE 2 O   1 ? 
ATOM   2698 C CB  . PHE B 1 118 ? -7.744  7.130   -7.569  0.670 18.480  0 120 PHE 2 CB  1 ? 
ATOM   2699 C CG  . PHE B 1 118 ? -6.260  7.038   -7.827  0.670 19.110  0 120 PHE 2 CG  1 ? 
ATOM   2700 C CD1 . PHE B 1 118 ? -5.347  7.122   -6.778  0.670 19.040  0 120 PHE 2 CD1 1 ? 
ATOM   2701 C CD2 . PHE B 1 118 ? -5.772  6.868   -9.114  0.670 18.750  0 120 PHE 2 CD2 1 ? 
ATOM   2702 C CE1 . PHE B 1 118 ? -3.985  6.980   -7.015  0.670 19.320  0 120 PHE 2 CE1 1 ? 
ATOM   2703 C CE2 . PHE B 1 118 ? -4.414  6.729   -9.349  0.670 18.630  0 120 PHE 2 CE2 1 ? 
ATOM   2704 C CZ  . PHE B 1 118 ? -3.523  6.778   -8.303  0.670 20.060  0 120 PHE 2 CZ  1 ? 
ATOM   2705 N N   . TYR B 1 119 ? -7.309  4.500   -5.241  0.670 21.560  0 121 TYR 2 N   1 ? 
ATOM   2706 C CA  . TYR B 1 119 ? -6.811  4.145   -3.880  0.670 21.700  0 121 TYR 2 CA  1 ? 
ATOM   2707 C C   . TYR B 1 119 ? -5.308  3.923   -3.944  0.670 20.930  0 121 TYR 2 C   1 ? 
ATOM   2708 O O   . TYR B 1 119 ? -4.826  3.154   -4.812  0.670 19.790  0 121 TYR 2 O   1 ? 
ATOM   2709 C CB  . TYR B 1 119 ? -7.574  2.946   -3.301  0.670 21.630  0 121 TYR 2 CB  1 ? 
ATOM   2710 C CG  . TYR B 1 119 ? -9.061  3.177   -3.338  0.670 24.590  0 121 TYR 2 CG  1 ? 
ATOM   2711 C CD1 . TYR B 1 119 ? -9.641  4.160   -2.551  0.670 26.290  0 121 TYR 2 CD1 1 ? 
ATOM   2712 C CD2 . TYR B 1 119 ? -9.873  2.496   -4.231  0.670 25.200  0 121 TYR 2 CD2 1 ? 
ATOM   2713 C CE1 . TYR B 1 119 ? -10.995 4.444   -2.622  0.670 25.980  0 121 TYR 2 CE1 1 ? 
ATOM   2714 C CE2 . TYR B 1 119 ? -11.230 2.756   -4.298  0.670 26.220  0 121 TYR 2 CE2 1 ? 
ATOM   2715 C CZ  . TYR B 1 119 ? -11.790 3.737   -3.500  0.670 26.600  0 121 TYR 2 CZ  1 ? 
ATOM   2716 O OH  . TYR B 1 119 ? -13.128 3.996   -3.568  0.670 30.700  0 121 TYR 2 OH  1 ? 
ATOM   2717 N N   . GLY B 1 120 ? -4.582  4.627   -3.080  0.670 18.820  0 122 GLY 2 N   1 ? 
ATOM   2718 C CA  . GLY B 1 120 ? -3.118  4.542   -2.989  0.670 20.840  0 122 GLY 2 CA  1 ? 
ATOM   2719 C C   . GLY B 1 120 ? -2.657  4.339   -1.556  0.670 20.420  0 122 GLY 2 C   1 ? 
ATOM   2720 O O   . GLY B 1 120 ? -3.293  4.902   -0.662  0.670 20.460  0 122 GLY 2 O   1 ? 
ATOM   2721 N N   . THR B 1 121 ? -1.592  3.563   -1.369  0.670 21.220  0 123 THR 2 N   1 ? 
ATOM   2722 C CA  . THR B 1 121 ? -1.058  3.191   -0.031  0.670 21.550  0 123 THR 2 CA  1 ? 
ATOM   2723 C C   . THR B 1 121 ? 0.428   2.846   -0.121  0.670 21.470  0 123 THR 2 C   1 ? 
ATOM   2724 O O   . THR B 1 121 ? 0.952   2.665   -1.251  0.670 19.200  0 123 THR 2 O   1 ? 
ATOM   2725 C CB  . THR B 1 121 ? -1.895  2.067   0.597   0.670 25.460  0 123 THR 2 CB  1 ? 
ATOM   2726 O OG1 . THR B 1 121 ? -1.561  2.090   1.989   0.670 30.460  0 123 THR 2 OG1 1 ? 
ATOM   2727 C CG2 . THR B 1 121 ? -1.657  0.725   -0.056  0.670 23.690  0 123 THR 2 CG2 1 ? 
ATOM   2728 N N   . ASN B 1 122 ? 1.098   2.895   1.037   0.670 22.130  0 124 ASN 2 N   1 ? 
ATOM   2729 C CA  . ASN B 1 122 ? 2.497   2.462   1.257   0.670 24.020  0 124 ASN 2 CA  1 ? 
ATOM   2730 C C   . ASN B 1 122 ? 3.465   3.417   0.575   0.670 22.090  0 124 ASN 2 C   1 ? 
ATOM   2731 O O   . ASN B 1 122 ? 4.584   2.986   0.249   0.670 23.480  0 124 ASN 2 O   1 ? 
ATOM   2732 C CB  . ASN B 1 122 ? 2.737   1.044   0.731   0.670 27.910  0 124 ASN 2 CB  1 ? 
ATOM   2733 C CG  . ASN B 1 122 ? 3.807   0.331   1.518   0.670 36.300  0 124 ASN 2 CG  1 ? 
ATOM   2734 O OD1 . ASN B 1 122 ? 3.786   0.372   2.753   0.670 42.140  0 124 ASN 2 OD1 1 ? 
ATOM   2735 N ND2 . ASN B 1 122 ? 4.728   -0.320  0.818   0.670 40.660  0 124 ASN 2 ND2 1 ? 
ATOM   2736 N N   . PHE B 1 123 ? 3.071   4.657   0.314   0.670 21.130  0 125 PHE 2 N   1 ? 
ATOM   2737 C CA  . PHE B 1 123 ? 4.034   5.688   -0.153  0.670 21.070  0 125 PHE 2 CA  1 ? 
ATOM   2738 C C   . PHE B 1 123 ? 4.848   6.103   1.067   0.670 20.150  0 125 PHE 2 C   1 ? 
ATOM   2739 O O   . PHE B 1 123 ? 4.261   6.405   2.106   0.670 19.960  0 125 PHE 2 O   1 ? 
ATOM   2740 C CB  . PHE B 1 123 ? 3.316   6.865   -0.806  0.670 20.600  0 125 PHE 2 CB  1 ? 
ATOM   2741 C CG  . PHE B 1 123 ? 2.822   6.556   -2.193  0.670 20.800  0 125 PHE 2 CG  1 ? 
ATOM   2742 C CD1 . PHE B 1 123 ? 3.718   6.418   -3.239  0.670 21.480  0 125 PHE 2 CD1 1 ? 
ATOM   2743 C CD2 . PHE B 1 123 ? 1.470   6.461   -2.460  0.670 21.430  0 125 PHE 2 CD2 1 ? 
ATOM   2744 C CE1 . PHE B 1 123 ? 3.279   6.094   -4.508  0.670 21.210  0 125 PHE 2 CE1 1 ? 
ATOM   2745 C CE2 . PHE B 1 123 ? 1.033   6.151   -3.740  0.670 24.280  0 125 PHE 2 CE2 1 ? 
ATOM   2746 C CZ  . PHE B 1 123 ? 1.939   5.992   -4.769  0.670 21.120  0 125 PHE 2 CZ  1 ? 
ATOM   2747 N N   . PRO B 1 124 ? 6.198   6.040   1.003   0.670 22.010  0 126 PRO 2 N   1 ? 
ATOM   2748 C CA  . PRO B 1 124 ? 7.027   6.478   2.119   0.670 21.480  0 126 PRO 2 CA  1 ? 
ATOM   2749 C C   . PRO B 1 124 ? 6.855   7.992   2.306   0.670 20.390  0 126 PRO 2 C   1 ? 
ATOM   2750 O O   . PRO B 1 124 ? 6.803   8.714   1.319   0.670 19.050  0 126 PRO 2 O   1 ? 
ATOM   2751 C CB  . PRO B 1 124 ? 8.459   6.103   1.722   0.670 21.850  0 126 PRO 2 CB  1 ? 
ATOM   2752 C CG  . PRO B 1 124 ? 8.415   5.945   0.218   0.670 22.400  0 126 PRO 2 CG  1 ? 
ATOM   2753 C CD  . PRO B 1 124 ? 6.996   5.547   -0.135  0.670 21.740  0 126 PRO 2 CD  1 ? 
ATOM   2754 N N   . ALA B 1 125 ? 6.795   8.445   3.555   0.670 20.060  0 127 ALA 2 N   1 ? 
ATOM   2755 C CA  . ALA B 1 125 ? 6.534   9.863   3.888   0.670 20.930  0 127 ALA 2 CA  1 ? 
ATOM   2756 C C   . ALA B 1 125 ? 7.648   10.764  3.329   0.670 21.280  0 127 ALA 2 C   1 ? 
ATOM   2757 O O   . ALA B 1 125 ? 7.329   11.913  2.959   0.670 23.560  0 127 ALA 2 O   1 ? 
ATOM   2758 C CB  . ALA B 1 125 ? 6.362   10.013  5.366   0.670 24.030  0 127 ALA 2 CB  1 ? 
ATOM   2759 N N   . ASN B 1 126 ? 8.875   10.254  3.169   0.670 21.250  0 128 ASN 2 N   1 ? 
ATOM   2760 C CA  . ASN B 1 126 ? 10.051  11.013  2.656   0.670 23.890  0 128 ASN 2 CA  1 ? 
ATOM   2761 C C   . ASN B 1 126 ? 10.236  10.823  1.140   0.670 23.070  0 128 ASN 2 C   1 ? 
ATOM   2762 O O   . ASN B 1 126 ? 11.175  11.395  0.596   0.670 20.730  0 128 ASN 2 O   1 ? 
ATOM   2763 C CB  . ASN B 1 126 ? 11.321  10.632  3.397   0.670 27.390  0 128 ASN 2 CB  1 ? 
ATOM   2764 C CG  . ASN B 1 126 ? 11.712  9.198   3.139   0.670 32.430  0 128 ASN 2 CG  1 ? 
ATOM   2765 O OD1 . ASN B 1 126 ? 10.847  8.309   3.060   0.670 31.750  0 128 ASN 2 OD1 1 ? 
ATOM   2766 N ND2 . ASN B 1 126 ? 13.015  8.964   3.058   0.670 36.410  0 128 ASN 2 ND2 1 ? 
ATOM   2767 N N   . GLY B 1 127 ? 9.318   10.115  0.470   0.670 22.220  0 129 GLY 2 N   1 ? 
ATOM   2768 C CA  . GLY B 1 127 ? 9.424   9.792   -0.961  0.670 21.410  0 129 GLY 2 CA  1 ? 
ATOM   2769 C C   . GLY B 1 127 ? 8.904   10.916  -1.856  0.670 19.960  0 129 GLY 2 C   1 ? 
ATOM   2770 O O   . GLY B 1 127 ? 8.274   11.868  -1.395  0.670 18.040  0 129 GLY 2 O   1 ? 
ATOM   2771 N N   . PRO B 1 128 ? 9.219   10.879  -3.164  0.670 19.250  0 130 PRO 2 N   1 ? 
ATOM   2772 C CA  . PRO B 1 128 ? 8.898   11.985  -4.062  0.670 18.670  0 130 PRO 2 CA  1 ? 
ATOM   2773 C C   . PRO B 1 128 ? 7.398   12.244  -4.272  0.670 18.520  0 130 PRO 2 C   1 ? 
ATOM   2774 O O   . PRO B 1 128 ? 7.070   13.376  -4.601  0.670 19.080  0 130 PRO 2 O   1 ? 
ATOM   2775 C CB  . PRO B 1 128 ? 9.620   11.599  -5.372  0.670 19.550  0 130 PRO 2 CB  1 ? 
ATOM   2776 C CG  . PRO B 1 128 ? 9.814   10.110  -5.301  0.670 20.430  0 130 PRO 2 CG  1 ? 
ATOM   2777 C CD  . PRO B 1 128 ? 9.980   9.814   -3.836  0.670 20.630  0 130 PRO 2 CD  1 ? 
ATOM   2778 N N   . VAL B 1 129 ? 6.528   11.262  -4.008  0.670 16.700  0 131 VAL 2 N   1 ? 
ATOM   2779 C CA  . VAL B 1 129 ? 5.051   11.414  -4.113  0.670 17.850  0 131 VAL 2 CA  1 ? 
ATOM   2780 C C   . VAL B 1 129 ? 4.545   12.276  -2.939  0.670 15.960  0 131 VAL 2 C   1 ? 
ATOM   2781 O O   . VAL B 1 129 ? 3.984   13.345  -3.159  0.670 16.020  0 131 VAL 2 O   1 ? 
ATOM   2782 C CB  . VAL B 1 129 ? 4.352   10.048  -4.216  0.670 18.880  0 131 VAL 2 CB  1 ? 
ATOM   2783 C CG1 . VAL B 1 129 ? 2.864   10.165  -3.933  0.670 20.020  0 131 VAL 2 CG1 1 ? 
ATOM   2784 C CG2 . VAL B 1 129 ? 4.595   9.410   -5.573  0.670 20.720  0 131 VAL 2 CG2 1 ? 
ATOM   2785 N N   . MET B 1 130 ? 4.851   11.909  -1.718  0.670 16.660  0 132 MET 2 N   1 ? 
ATOM   2786 C CA  . MET B 1 130 ? 4.376   12.672  -0.532  0.670 18.040  0 132 MET 2 CA  1 ? 
ATOM   2787 C C   . MET B 1 130 ? 5.163   13.999  -0.343  0.670 17.750  0 132 MET 2 C   1 ? 
ATOM   2788 O O   . MET B 1 130 ? 4.622   14.871  0.336   0.670 21.260  0 132 MET 2 O   1 ? 
ATOM   2789 C CB  . MET B 1 130 ? 4.443   11.797  0.724   0.670 18.590  0 132 MET 2 CB  1 ? 
ATOM   2790 C CG  . MET B 1 130 ? 3.608   10.539  0.662   0.670 20.060  0 132 MET 2 CG  1 ? 
ATOM   2791 S SD  . MET B 1 130 ? 1.880   10.817  0.183   0.670 23.530  0 132 MET 2 SD  1 ? 
ATOM   2792 C CE  . MET B 1 130 ? 1.355   11.957  1.456   0.670 21.090  0 132 MET 2 CE  1 ? 
ATOM   2793 N N   . GLN B 1 131 ? 6.344   14.183  -0.949  0.670 16.750  0 133 GLN 2 N   1 ? 
ATOM   2794 C CA  . GLN B 1 131 ? 7.147   15.443  -0.837  0.670 16.440  0 133 GLN 2 CA  1 ? 
ATOM   2795 C C   . GLN B 1 131 ? 6.911   16.370  -2.046  0.670 17.290  0 133 GLN 2 C   1 ? 
ATOM   2796 O O   . GLN B 1 131 ? 7.458   17.506  -2.053  0.670 17.430  0 133 GLN 2 O   1 ? 
ATOM   2797 C CB  . GLN B 1 131 ? 8.631   15.132  -0.707  0.670 17.000  0 133 GLN 2 CB  1 ? 
ATOM   2798 C CG  . GLN B 1 131 ? 9.013   14.416  0.594   0.670 17.680  0 133 GLN 2 CG  1 ? 
ATOM   2799 C CD  . GLN B 1 131 ? 8.766   15.257  1.825   0.670 17.800  0 133 GLN 2 CD  1 ? 
ATOM   2800 O OE1 . GLN B 1 131 ? 8.964   16.463  1.815   0.670 16.970  0 133 GLN 2 OE1 1 ? 
ATOM   2801 N NE2 . GLN B 1 131 ? 8.330   14.618  2.901   0.670 18.150  0 133 GLN 2 NE2 1 ? 
ATOM   2802 N N   . LYS B 1 132 ? 6.138   15.899  -3.034  0.670 18.790  0 134 LYS 2 N   1 ? 
ATOM   2803 C CA  . LYS B 1 132 ? 5.734   16.655  -4.247  0.670 20.460  0 134 LYS 2 CA  1 ? 
ATOM   2804 C C   . LYS B 1 132 ? 6.967   17.066  -5.056  0.670 19.730  0 134 LYS 2 C   1 ? 
ATOM   2805 O O   . LYS B 1 132 ? 7.089   18.269  -5.346  0.670 18.990  0 134 LYS 2 O   1 ? 
ATOM   2806 C CB  . LYS B 1 132 ? 4.906   17.886  -3.881  0.670 21.050  0 134 LYS 2 CB  1 ? 
ATOM   2807 C CG  . LYS B 1 132 ? 3.610   17.558  -3.158  0.670 23.900  0 134 LYS 2 CG  1 ? 
ATOM   2808 C CD  . LYS B 1 132 ? 2.793   18.800  -2.904  0.670 26.060  0 134 LYS 2 CD  1 ? 
ATOM   2809 C CE  . LYS B 1 132 ? 1.590   18.557  -2.026  0.670 28.270  0 134 LYS 2 CE  1 ? 
ATOM   2810 N NZ  . LYS B 1 132 ? 0.836   19.818  -1.815  0.670 29.630  0 134 LYS 2 NZ  1 ? 
ATOM   2811 N N   . LYS B 1 133 ? 7.789   16.090  -5.443  0.670 18.810  0 135 LYS 2 N   1 ? 
ATOM   2812 C CA  . LYS B 1 133 ? 9.037   16.275  -6.223  0.670 20.490  0 135 LYS 2 CA  1 ? 
ATOM   2813 C C   . LYS B 1 133 ? 8.909   15.798  -7.678  0.670 20.230  0 135 LYS 2 C   1 ? 
ATOM   2814 O O   . LYS B 1 133 ? 9.961   15.702  -8.359  0.670 23.070  0 135 LYS 2 O   1 ? 
ATOM   2815 C CB  . LYS B 1 133 ? 10.155  15.492  -5.535  0.670 23.760  0 135 LYS 2 CB  1 ? 
ATOM   2816 C CG  . LYS B 1 133 ? 10.327  15.839  -4.074  0.670 28.250  0 135 LYS 2 CG  1 ? 
ATOM   2817 C CD  . LYS B 1 133 ? 10.905  17.220  -3.866  0.670 31.040  0 135 LYS 2 CD  1 ? 
ATOM   2818 C CE  . LYS B 1 133 ? 12.405  17.225  -4.019  0.670 34.600  0 135 LYS 2 CE  1 ? 
ATOM   2819 N NZ  . LYS B 1 133 ? 13.003  18.337  -3.255  0.670 38.030  0 135 LYS 2 NZ  1 ? 
ATOM   2820 N N   . THR B 1 134 ? 7.718   15.449  -8.155  0.670 19.270  0 136 THR 2 N   1 ? 
ATOM   2821 C CA  . THR B 1 134 ? 7.562   14.917  -9.534  0.670 18.290  0 136 THR 2 CA  1 ? 
ATOM   2822 C C   . THR B 1 134 ? 7.425   16.089  -10.515 0.670 20.710  0 136 THR 2 C   1 ? 
ATOM   2823 O O   . THR B 1 134 ? 6.905   17.165  -10.110 0.670 19.720  0 136 THR 2 O   1 ? 
ATOM   2824 C CB  . THR B 1 134 ? 6.397   13.928  -9.593  0.670 18.090  0 136 THR 2 CB  1 ? 
ATOM   2825 O OG1 . THR B 1 134 ? 5.197   14.670  -9.423  0.670 20.030  0 136 THR 2 OG1 1 ? 
ATOM   2826 C CG2 . THR B 1 134 ? 6.499   12.838  -8.557  0.670 17.200  0 136 THR 2 CG2 1 ? 
ATOM   2827 N N   . LEU B 1 135 ? 7.856   15.893  -11.768 0.670 20.910  0 137 LEU 2 N   1 ? 
ATOM   2828 C CA  . LEU B 1 135 ? 7.753   16.932  -12.831 0.670 20.140  0 137 LEU 2 CA  1 ? 
ATOM   2829 C C   . LEU B 1 135 ? 6.792   16.452  -13.923 0.670 19.750  0 137 LEU 2 C   1 ? 
ATOM   2830 O O   . LEU B 1 135 ? 5.974   17.274  -14.404 0.670 17.030  0 137 LEU 2 O   1 ? 
ATOM   2831 C CB  . LEU B 1 135 ? 9.147   17.212  -13.400 0.670 21.670  0 137 LEU 2 CB  1 ? 
ATOM   2832 C CG  . LEU B 1 135 ? 10.185  17.750  -12.411 0.670 25.790  0 137 LEU 2 CG  1 ? 
ATOM   2833 C CD1 . LEU B 1 135 ? 11.527  17.953  -13.107 0.670 27.920  0 137 LEU 2 CD1 1 ? 
ATOM   2834 C CD2 . LEU B 1 135 ? 9.723   19.054  -11.789 0.670 27.300  0 137 LEU 2 CD2 1 ? 
ATOM   2835 N N   . LYS B 1 136 ? 6.870   15.174  -14.328 0.670 19.080  0 138 LYS 2 N   1 ? 
ATOM   2836 C CA  . LYS B 1 136 ? 5.990   14.659  -15.398 0.670 19.990  0 138 LYS 2 CA  1 ? 
ATOM   2837 C C   . LYS B 1 136 ? 6.125   13.157  -15.593 0.670 19.000  0 138 LYS 2 C   1 ? 
ATOM   2838 O O   . LYS B 1 136 ? 7.106   12.605  -15.130 0.670 22.170  0 138 LYS 2 O   1 ? 
ATOM   2839 C CB  . LYS B 1 136 ? 6.326   15.301  -16.742 0.670 21.830  0 138 LYS 2 CB  1 ? 
ATOM   2840 C CG  . LYS B 1 136 ? 7.762   15.170  -17.205 0.670 24.230  0 138 LYS 2 CG  1 ? 
ATOM   2841 C CD  . LYS B 1 136 ? 7.949   15.781  -18.571 0.670 28.820  0 138 LYS 2 CD  1 ? 
ATOM   2842 C CE  . LYS B 1 136 ? 9.359   15.649  -19.096 0.670 32.950  0 138 LYS 2 CE  1 ? 
ATOM   2843 N NZ  . LYS B 1 136 ? 9.525   16.402  -20.369 0.670 34.400  0 138 LYS 2 NZ  1 ? 
ATOM   2844 N N   . TRP B 1 137 ? 5.188   12.562  -16.330 0.670 18.180  0 139 TRP 2 N   1 ? 
ATOM   2845 C CA  . TRP B 1 137 ? 5.319   11.203  -16.907 0.670 18.010  0 139 TRP 2 CA  1 ? 
ATOM   2846 C C   . TRP B 1 137 ? 6.181   11.297  -18.168 0.670 18.570  0 139 TRP 2 C   1 ? 
ATOM   2847 O O   . TRP B 1 137 ? 6.001   12.221  -18.947 0.670 19.880  0 139 TRP 2 O   1 ? 
ATOM   2848 C CB  . TRP B 1 137 ? 3.949   10.569  -17.213 0.670 18.690  0 139 TRP 2 CB  1 ? 
ATOM   2849 C CG  . TRP B 1 137 ? 3.167   10.205  -15.983 0.670 19.710  0 139 TRP 2 CG  1 ? 
ATOM   2850 C CD1 . TRP B 1 137 ? 2.094   10.872  -15.471 0.670 18.240  0 139 TRP 2 CD1 1 ? 
ATOM   2851 C CD2 . TRP B 1 137 ? 3.406   9.096   -15.098 0.670 18.720  0 139 TRP 2 CD2 1 ? 
ATOM   2852 N NE1 . TRP B 1 137 ? 1.655   10.257  -14.333 0.670 19.330  0 139 TRP 2 NE1 1 ? 
ATOM   2853 C CE2 . TRP B 1 137 ? 2.440   9.176   -14.072 0.670 18.920  0 139 TRP 2 CE2 1 ? 
ATOM   2854 C CE3 . TRP B 1 137 ? 4.339   8.059   -15.063 0.670 19.690  0 139 TRP 2 CE3 1 ? 
ATOM   2855 C CZ2 . TRP B 1 137 ? 2.363   8.247   -13.043 0.670 20.030  0 139 TRP 2 CZ2 1 ? 
ATOM   2856 C CZ3 . TRP B 1 137 ? 4.276   7.150   -14.031 0.670 20.530  0 139 TRP 2 CZ3 1 ? 
ATOM   2857 C CH2 . TRP B 1 137 ? 3.293   7.239   -13.045 0.670 19.080  0 139 TRP 2 CH2 1 ? 
ATOM   2858 N N   . GLU B 1 138 ? 7.096   10.365  -18.354 0.670 18.560  0 140 GLU 2 N   1 ? 
ATOM   2859 C CA  . GLU B 1 138 ? 7.759   10.186  -19.657 0.670 19.270  0 140 GLU 2 CA  1 ? 
ATOM   2860 C C   . GLU B 1 138 ? 6.752   9.524   -20.594 0.670 20.130  0 140 GLU 2 C   1 ? 
ATOM   2861 O O   . GLU B 1 138 ? 5.998   8.639   -20.179 0.670 19.490  0 140 GLU 2 O   1 ? 
ATOM   2862 C CB  . GLU B 1 138 ? 9.050   9.380   -19.514 0.670 19.430  0 140 GLU 2 CB  1 ? 
ATOM   2863 C CG  . GLU B 1 138 ? 10.111  10.103  -18.689 0.670 21.110  0 140 GLU 2 CG  1 ? 
ATOM   2864 C CD  . GLU B 1 138 ? 10.760  11.318  -19.336 0.670 20.920  0 140 GLU 2 CD  1 ? 
ATOM   2865 O OE1 . GLU B 1 138 ? 10.333  11.731  -20.435 0.670 22.730  0 140 GLU 2 OE1 1 ? 
ATOM   2866 O OE2 . GLU B 1 138 ? 11.693  11.845  -18.729 0.670 23.190  0 140 GLU 2 OE2 1 ? 
ATOM   2867 N N   . PRO B 1 139 ? 6.759   9.903   -21.888 0.670 19.220  0 141 PRO 2 N   1 ? 
ATOM   2868 C CA  . PRO B 1 139 ? 5.962   9.212   -22.900 0.670 20.000  0 141 PRO 2 CA  1 ? 
ATOM   2869 C C   . PRO B 1 139 ? 6.362   7.735   -22.924 0.670 19.670  0 141 PRO 2 C   1 ? 
ATOM   2870 O O   . PRO B 1 139 ? 7.530   7.456   -22.695 0.670 18.400  0 141 PRO 2 O   1 ? 
ATOM   2871 C CB  . PRO B 1 139 ? 6.344   9.914   -24.214 0.670 20.700  0 141 PRO 2 CB  1 ? 
ATOM   2872 C CG  . PRO B 1 139 ? 6.837   11.263  -23.767 0.670 22.000  0 141 PRO 2 CG  1 ? 
ATOM   2873 C CD  . PRO B 1 139 ? 7.513   11.040  -22.439 0.670 21.250  0 141 PRO 2 CD  1 ? 
ATOM   2874 N N   . SER B 1 140 ? 5.417   6.836   -23.172 0.670 20.000  0 142 SER 2 N   1 ? 
ATOM   2875 C CA  . SER B 1 140 ? 5.677   5.383   -23.111 0.670 22.440  0 142 SER 2 CA  1 ? 
ATOM   2876 C C   . SER B 1 140 ? 4.767   4.651   -24.094 0.670 22.760  0 142 SER 2 C   1 ? 
ATOM   2877 O O   . SER B 1 140 ? 3.906   5.298   -24.712 0.670 20.760  0 142 SER 2 O   1 ? 
ATOM   2878 C CB  . SER B 1 140 ? 5.508   4.887   -21.698 0.670 24.790  0 142 SER 2 CB  1 ? 
ATOM   2879 O OG  . SER B 1 140 ? 4.342   5.448   -21.112 0.670 29.430  0 142 SER 2 OG  1 ? 
ATOM   2880 N N   . THR B 1 141 ? 4.972   3.343   -24.212 0.670 20.700  0 143 THR 2 N   1 ? 
ATOM   2881 C CA  . THR B 1 141 ? 4.215   2.453   -25.117 0.670 21.450  0 143 THR 2 CA  1 ? 
ATOM   2882 C C   . THR B 1 141 ? 3.513   1.390   -24.278 0.670 19.610  0 143 THR 2 C   1 ? 
ATOM   2883 O O   . THR B 1 141 ? 4.205   0.688   -23.526 0.670 21.880  0 143 THR 2 O   1 ? 
ATOM   2884 C CB  . THR B 1 141 ? 5.123   1.815   -26.174 0.670 21.270  0 143 THR 2 CB  1 ? 
ATOM   2885 O OG1 . THR B 1 141 ? 5.715   2.873   -26.933 0.670 19.610  0 143 THR 2 OG1 1 ? 
ATOM   2886 C CG2 . THR B 1 141 ? 4.349   0.900   -27.098 0.670 20.140  0 143 THR 2 CG2 1 ? 
ATOM   2887 N N   . GLU B 1 142 ? 2.190   1.326   -24.381 0.670 19.240  0 144 GLU 2 N   1 ? 
ATOM   2888 C CA  . GLU B 1 142 ? 1.345   0.292   -23.737 0.670 17.820  0 144 GLU 2 CA  1 ? 
ATOM   2889 C C   . GLU B 1 142 ? 1.393   -0.941  -24.642 0.670 19.610  0 144 GLU 2 C   1 ? 
ATOM   2890 O O   . GLU B 1 142 ? 1.223   -0.771  -25.874 0.670 18.500  0 144 GLU 2 O   1 ? 
ATOM   2891 C CB  . GLU B 1 142 ? -0.063  0.843   -23.525 0.670 18.060  0 144 GLU 2 CB  1 ? 
ATOM   2892 C CG  . GLU B 1 142 ? -1.026  -0.105  -22.826 0.670 16.570  0 144 GLU 2 CG  1 ? 
ATOM   2893 C CD  . GLU B 1 142 ? -2.399  0.468   -22.548 0.670 18.770  0 144 GLU 2 CD  1 ? 
ATOM   2894 O OE1 . GLU B 1 142 ? -2.766  1.479   -23.206 0.670 20.530  0 144 GLU 2 OE1 1 ? 
ATOM   2895 O OE2 . GLU B 1 142 ? -3.107  -0.107  -21.695 0.670 20.600  0 144 GLU 2 OE2 1 ? 
ATOM   2896 N N   . LYS B 1 143 ? 1.697   -2.106  -24.080 0.670 20.400  0 145 LYS 2 N   1 ? 
ATOM   2897 C CA  . LYS B 1 143 ? 1.643   -3.397  -24.811 0.670 22.730  0 145 LYS 2 CA  1 ? 
ATOM   2898 C C   . LYS B 1 143 ? 0.280   -4.006  -24.536 0.670 19.950  0 145 LYS 2 C   1 ? 
ATOM   2899 O O   . LYS B 1 143 ? 0.012   -4.334  -23.370 0.670 21.390  0 145 LYS 2 O   1 ? 
ATOM   2900 C CB  . LYS B 1 143 ? 2.722   -4.391  -24.381 0.670 27.630  0 145 LYS 2 CB  1 ? 
ATOM   2901 C CG  . LYS B 1 143 ? 4.153   -3.974  -24.691 0.670 36.570  0 145 LYS 2 CG  1 ? 
ATOM   2902 C CD  . LYS B 1 143 ? 5.203   -4.861  -23.997 0.670 43.510  0 145 LYS 2 CD  1 ? 
ATOM   2903 C CE  . LYS B 1 143 ? 6.610   -4.289  -24.019 0.670 45.960  0 145 LYS 2 CE  1 ? 
ATOM   2904 N NZ  . LYS B 1 143 ? 7.268   -4.497  -25.331 0.670 49.750  0 145 LYS 2 NZ  1 ? 
ATOM   2905 N N   . MET B 1 144 ? -0.535  -4.169  -25.567 0.670 20.760  0 146 MET 2 N   1 ? 
ATOM   2906 C CA  . MET B 1 144 ? -1.911  -4.736  -25.479 0.670 20.810  0 146 MET 2 CA  1 ? 
ATOM   2907 C C   . MET B 1 144 ? -1.898  -6.215  -25.876 0.670 19.330  0 146 MET 2 C   1 ? 
ATOM   2908 O O   . MET B 1 144 ? -1.353  -6.552  -26.934 0.670 18.880  0 146 MET 2 O   1 ? 
ATOM   2909 C CB  . MET B 1 144 ? -2.853  -3.985  -26.418 0.670 23.880  0 146 MET 2 CB  1 ? 
ATOM   2910 C CG  . MET B 1 144 ? -3.038  -2.528  -26.017 0.670 27.070  0 146 MET 2 CG  1 ? 
ATOM   2911 S SD  . MET B 1 144 ? -4.131  -2.366  -24.577 0.670 28.740  0 146 MET 2 SD  1 ? 
ATOM   2912 C CE  . MET B 1 144 ? -4.723  -0.688  -24.784 0.670 31.680  0 146 MET 2 CE  1 ? 
ATOM   2913 N N   . TYR B 1 145 ? -2.546  -7.058  -25.097 0.670 18.050  0 147 TYR 2 N   1 ? 
ATOM   2914 C CA  . TYR B 1 145 ? -2.630  -8.504  -25.396 0.670 19.770  0 147 TYR 2 CA  1 ? 
ATOM   2915 C C   . TYR B 1 145 ? -3.793  -9.095  -24.606 0.670 20.500  0 147 TYR 2 C   1 ? 
ATOM   2916 O O   . TYR B 1 145 ? -4.337  -8.464  -23.720 0.670 21.260  0 147 TYR 2 O   1 ? 
ATOM   2917 C CB  . TYR B 1 145 ? -1.275  -9.183  -25.113 0.670 20.550  0 147 TYR 2 CB  1 ? 
ATOM   2918 C CG  . TYR B 1 145 ? -0.838  -9.095  -23.671 0.670 19.000  0 147 TYR 2 CG  1 ? 
ATOM   2919 C CD1 . TYR B 1 145 ? -0.138  -7.998  -23.207 0.670 20.030  0 147 TYR 2 CD1 1 ? 
ATOM   2920 C CD2 . TYR B 1 145 ? -1.164  -10.088 -22.761 0.670 20.030  0 147 TYR 2 CD2 1 ? 
ATOM   2921 C CE1 . TYR B 1 145 ? 0.207   -7.871  -21.869 0.670 19.780  0 147 TYR 2 CE1 1 ? 
ATOM   2922 C CE2 . TYR B 1 145 ? -0.833  -9.976  -21.421 0.670 19.890  0 147 TYR 2 CE2 1 ? 
ATOM   2923 C CZ  . TYR B 1 145 ? -0.137  -8.866  -20.975 0.670 20.090  0 147 TYR 2 CZ  1 ? 
ATOM   2924 O OH  . TYR B 1 145 ? 0.269   -8.762  -19.679 0.670 19.440  0 147 TYR 2 OH  1 ? 
ATOM   2925 N N   . VAL B 1 146 ? -4.082  -10.359 -24.878 0.670 21.610  0 148 VAL 2 N   1 ? 
ATOM   2926 C CA  . VAL B 1 146 ? -5.123  -11.123 -24.163 0.670 24.310  0 148 VAL 2 CA  1 ? 
ATOM   2927 C C   . VAL B 1 146 ? -4.425  -12.070 -23.193 0.670 26.280  0 148 VAL 2 C   1 ? 
ATOM   2928 O O   . VAL B 1 146 ? -3.493  -12.772 -23.605 0.670 27.110  0 148 VAL 2 O   1 ? 
ATOM   2929 C CB  . VAL B 1 146 ? -6.022  -11.842 -25.178 0.670 24.760  0 148 VAL 2 CB  1 ? 
ATOM   2930 C CG1 . VAL B 1 146 ? -7.049  -12.704 -24.496 0.670 25.470  0 148 VAL 2 CG1 1 ? 
ATOM   2931 C CG2 . VAL B 1 146 ? -6.671  -10.844 -26.125 0.670 25.060  0 148 VAL 2 CG2 1 ? 
ATOM   2932 N N   . ARG B 1 147 ? -4.865  -12.051 -21.940 0.670 29.680  0 149 ARG 2 N   1 ? 
ATOM   2933 C CA  . ARG B 1 147 ? -4.539  -13.069 -20.920 0.670 32.160  0 149 ARG 2 CA  1 ? 
ATOM   2934 C C   . ARG B 1 147 ? -5.858  -13.532 -20.295 0.670 35.320  0 149 ARG 2 C   1 ? 
ATOM   2935 O O   . ARG B 1 147 ? -6.645  -12.672 -19.871 0.670 30.380  0 149 ARG 2 O   1 ? 
ATOM   2936 C CB  . ARG B 1 147 ? -3.607  -12.463 -19.875 0.670 39.940  0 149 ARG 2 CB  1 ? 
ATOM   2937 C CG  . ARG B 1 147 ? -3.169  -13.441 -18.788 0.670 45.540  0 149 ARG 2 CG  1 ? 
ATOM   2938 C CD  . ARG B 1 147 ? -3.119  -12.747 -17.440 0.670 53.340  0 149 ARG 2 CD  1 ? 
ATOM   2939 N NE  . ARG B 1 147 ? -2.054  -13.236 -16.569 0.670 60.270  0 149 ARG 2 NE  1 ? 
ATOM   2940 C CZ  . ARG B 1 147 ? -0.909  -12.600 -16.329 0.670 66.760  0 149 ARG 2 CZ  1 ? 
ATOM   2941 N NH1 . ARG B 1 147 ? -0.636  -11.439 -16.912 0.670 74.010  0 149 ARG 2 NH1 1 ? 
ATOM   2942 N NH2 . ARG B 1 147 ? -0.028  -13.143 -15.510 0.670 67.510  0 149 ARG 2 NH2 1 ? 
ATOM   2943 N N   . ASP B 1 148 ? -6.099  -14.842 -20.293 0.670 37.750  0 150 ASP 2 N   1 ? 
ATOM   2944 C CA  . ASP B 1 148 ? -7.275  -15.496 -19.657 0.670 38.320  0 150 ASP 2 CA  1 ? 
ATOM   2945 C C   . ASP B 1 148 ? -8.577  -14.965 -20.274 0.670 34.540  0 150 ASP 2 C   1 ? 
ATOM   2946 O O   . ASP B 1 148 ? -9.580  -14.848 -19.549 0.670 33.550  0 150 ASP 2 O   1 ? 
ATOM   2947 C CB  . ASP B 1 148 ? -7.219  -15.324 -18.135 0.670 41.480  0 150 ASP 2 CB  1 ? 
ATOM   2948 C CG  . ASP B 1 148 ? -8.060  -16.335 -17.371 0.670 43.680  0 150 ASP 2 CG  1 ? 
ATOM   2949 O OD1 . ASP B 1 148 ? -8.404  -17.385 -17.964 0.670 45.630  0 150 ASP 2 OD1 1 ? 
ATOM   2950 O OD2 . ASP B 1 148 ? -8.377  -16.060 -16.191 0.670 47.360  0 150 ASP 2 OD2 1 ? 
ATOM   2951 N N   . GLY B 1 149 ? -8.579  -14.674 -21.578 0.670 28.610  0 151 GLY 2 N   1 ? 
ATOM   2952 C CA  . GLY B 1 149 ? -9.748  -14.133 -22.283 0.670 25.880  0 151 GLY 2 CA  1 ? 
ATOM   2953 C C   . GLY B 1 149 ? -10.039 -12.671 -21.942 0.670 28.160  0 151 GLY 2 C   1 ? 
ATOM   2954 O O   . GLY B 1 149 ? -11.167 -12.195 -22.267 0.670 26.310  0 151 GLY 2 O   1 ? 
ATOM   2955 N N   . VAL B 1 150 ? -9.068  -11.931 -21.391 0.670 25.070  0 152 VAL 2 N   1 ? 
ATOM   2956 C CA  . VAL B 1 150 ? -9.281  -10.512 -20.986 0.670 23.690  0 152 VAL 2 CA  1 ? 
ATOM   2957 C C   . VAL B 1 150 ? -8.247  -9.598  -21.653 0.670 20.670  0 152 VAL 2 C   1 ? 
ATOM   2958 O O   . VAL B 1 150 ? -7.064  -9.899  -21.608 0.670 20.870  0 152 VAL 2 O   1 ? 
ATOM   2959 C CB  . VAL B 1 150 ? -9.263  -10.393 -19.452 0.670 24.110  0 152 VAL 2 CB  1 ? 
ATOM   2960 C CG1 . VAL B 1 150 ? -9.276  -8.944  -18.996 0.670 25.900  0 152 VAL 2 CG1 1 ? 
ATOM   2961 C CG2 . VAL B 1 150 ? -10.432 -11.131 -18.857 0.670 27.210  0 152 VAL 2 CG2 1 ? 
ATOM   2962 N N   . LEU B 1 151 ? -8.682  -8.482  -22.229 0.670 19.800  0 153 LEU 2 N   1 ? 
ATOM   2963 C CA  . LEU B 1 151 ? -7.766  -7.518  -22.864 0.670 18.550  0 153 LEU 2 CA  1 ? 
ATOM   2964 C C   . LEU B 1 151 ? -6.965  -6.830  -21.760 0.670 18.190  0 153 LEU 2 C   1 ? 
ATOM   2965 O O   . LEU B 1 151 ? -7.600  -6.227  -20.863 0.670 20.570  0 153 LEU 2 O   1 ? 
ATOM   2966 C CB  . LEU B 1 151 ? -8.549  -6.515  -23.704 0.670 19.390  0 153 LEU 2 CB  1 ? 
ATOM   2967 C CG  . LEU B 1 151 ? -7.679  -5.451  -24.354 0.670 20.800  0 153 LEU 2 CG  1 ? 
ATOM   2968 C CD1 . LEU B 1 151 ? -6.606  -6.094  -25.214 0.670 21.860  0 153 LEU 2 CD1 1 ? 
ATOM   2969 C CD2 . LEU B 1 151 ? -8.536  -4.489  -25.158 0.670 22.520  0 153 LEU 2 CD2 1 ? 
ATOM   2970 N N   . THR B 1 152 ? -5.639  -6.967  -21.819 0.670 19.490  0 154 THR 2 N   1 ? 
ATOM   2971 C CA  . THR B 1 152 ? -4.649  -6.540  -20.793 0.670 18.990  0 154 THR 2 CA  1 ? 
ATOM   2972 C C   . THR B 1 152 ? -3.675  -5.583  -21.458 0.670 20.210  0 154 THR 2 C   1 ? 
ATOM   2973 O O   . THR B 1 152 ? -3.254  -5.851  -22.621 0.670 17.780  0 154 THR 2 O   1 ? 
ATOM   2974 C CB  . THR B 1 152 ? -3.913  -7.728  -20.145 0.670 19.610  0 154 THR 2 CB  1 ? 
ATOM   2975 O OG1 . THR B 1 152 ? -4.918  -8.643  -19.715 0.670 20.000  0 154 THR 2 OG1 1 ? 
ATOM   2976 C CG2 . THR B 1 152 ? -3.078  -7.332  -18.947 0.670 19.360  0 154 THR 2 CG2 1 ? 
ATOM   2977 N N   . GLY B 1 153 ? -3.351  -4.481  -20.768 0.670 19.750  0 155 GLY 2 N   1 ? 
ATOM   2978 C CA  . GLY B 1 153 ? -2.345  -3.491  -21.203 0.670 19.080  0 155 GLY 2 CA  1 ? 
ATOM   2979 C C   . GLY B 1 153 ? -1.277  -3.299  -20.146 0.670 18.590  0 155 GLY 2 C   1 ? 
ATOM   2980 O O   . GLY B 1 153 ? -1.630  -2.947  -19.017 0.670 19.770  0 155 GLY 2 O   1 ? 
ATOM   2981 N N   . ASP B 1 154 ? -0.016  -3.546  -20.502 0.670 20.300  0 156 ASP 2 N   1 ? 
ATOM   2982 C CA  . ASP B 1 154 ? 1.176   -3.376  -19.627 0.670 21.790  0 156 ASP 2 CA  1 ? 
ATOM   2983 C C   . ASP B 1 154 ? 1.999   -2.166  -20.092 0.670 21.990  0 156 ASP 2 C   1 ? 
ATOM   2984 O O   . ASP B 1 154 ? 2.205   -2.001  -21.300 0.670 21.680  0 156 ASP 2 O   1 ? 
ATOM   2985 C CB  . ASP B 1 154 ? 2.050   -4.628  -19.647 0.670 22.860  0 156 ASP 2 CB  1 ? 
ATOM   2986 C CG  . ASP B 1 154 ? 1.484   -5.794  -18.862 0.670 24.090  0 156 ASP 2 CG  1 ? 
ATOM   2987 O OD1 . ASP B 1 154 ? 0.522   -5.599  -18.109 0.670 24.670  0 156 ASP 2 OD1 1 ? 
ATOM   2988 O OD2 . ASP B 1 154 ? 2.007   -6.891  -19.023 0.670 25.250  0 156 ASP 2 OD2 1 ? 
ATOM   2989 N N   . VAL B 1 155 ? 2.464   -1.347  -19.155 0.670 21.430  0 157 VAL 2 N   1 ? 
ATOM   2990 C CA  . VAL B 1 155 ? 3.407   -0.217  -19.407 0.670 22.430  0 157 VAL 2 CA  1 ? 
ATOM   2991 C C   . VAL B 1 155 ? 4.538   -0.325  -18.381 0.670 21.550  0 157 VAL 2 C   1 ? 
ATOM   2992 O O   . VAL B 1 155 ? 4.238   -0.608  -17.242 0.670 21.060  0 157 VAL 2 O   1 ? 
ATOM   2993 C CB  . VAL B 1 155 ? 2.704   1.146   -19.265 0.670 23.370  0 157 VAL 2 CB  1 ? 
ATOM   2994 C CG1 . VAL B 1 155 ? 3.688   2.277   -19.104 0.670 25.670  0 157 VAL 2 CG1 1 ? 
ATOM   2995 C CG2 . VAL B 1 155 ? 1.774   1.419   -20.411 0.670 24.930  0 157 VAL 2 CG2 1 ? 
ATOM   2996 N N   . GLU B 1 156 ? 5.781   -0.107  -18.787 0.670 23.600  0 158 GLU 2 N   1 ? 
ATOM   2997 C CA  . GLU B 1 156 ? 6.915   0.182   -17.867 0.670 25.960  0 158 GLU 2 CA  1 ? 
ATOM   2998 C C   . GLU B 1 156 ? 7.358   1.609   -18.162 0.670 22.480  0 158 GLU 2 C   1 ? 
ATOM   2999 O O   . GLU B 1 156 ? 7.741   1.891   -19.288 0.670 21.470  0 158 GLU 2 O   1 ? 
ATOM   3000 C CB  . GLU B 1 156 ? 8.102   -0.776  -18.061 0.670 29.610  0 158 GLU 2 CB  1 ? 
ATOM   3001 C CG  . GLU B 1 156 ? 7.735   -2.251  -17.979 0.670 35.660  0 158 GLU 2 CG  1 ? 
ATOM   3002 C CD  . GLU B 1 156 ? 8.941   -3.179  -18.073 0.670 42.410  0 158 GLU 2 CD  1 ? 
ATOM   3003 O OE1 . GLU B 1 156 ? 10.031  -2.783  -17.562 0.670 41.720  0 158 GLU 2 OE1 1 ? 
ATOM   3004 O OE2 . GLU B 1 156 ? 8.804   -4.275  -18.697 0.670 50.260  0 158 GLU 2 OE2 1 ? 
ATOM   3005 N N   . THR B 1 157 ? 7.214   2.513   -17.214 0.670 22.060  0 159 THR 2 N   1 ? 
ATOM   3006 C CA  . THR B 1 157 ? 7.525   3.942   -17.467 0.670 22.050  0 159 THR 2 CA  1 ? 
ATOM   3007 C C   . THR B 1 157 ? 8.035   4.556   -16.164 0.670 19.540  0 159 THR 2 C   1 ? 
ATOM   3008 O O   . THR B 1 157 ? 8.350   3.821   -15.211 0.670 18.860  0 159 THR 2 O   1 ? 
ATOM   3009 C CB  . THR B 1 157 ? 6.338   4.649   -18.148 0.670 23.080  0 159 THR 2 CB  1 ? 
ATOM   3010 O OG1 . THR B 1 157 ? 6.731   5.968   -18.556 0.670 22.540  0 159 THR 2 OG1 1 ? 
ATOM   3011 C CG2 . THR B 1 157 ? 5.104   4.750   -17.275 0.670 23.930  0 159 THR 2 CG2 1 ? 
ATOM   3012 N N   . ALA B 1 158 ? 8.174   5.863   -16.162 0.670 19.240  0 160 ALA 2 N   1 ? 
ATOM   3013 C CA  . ALA B 1 158 ? 8.841   6.608   -15.084 0.670 19.870  0 160 ALA 2 CA  1 ? 
ATOM   3014 C C   . ALA B 1 158 ? 8.235   7.993   -14.973 0.670 18.970  0 160 ALA 2 C   1 ? 
ATOM   3015 O O   . ALA B 1 158 ? 7.862   8.558   -16.013 0.670 21.150  0 160 ALA 2 O   1 ? 
ATOM   3016 C CB  . ALA B 1 158 ? 10.311  6.714   -15.401 0.670 21.860  0 160 ALA 2 CB  1 ? 
ATOM   3017 N N   . LEU B 1 159 ? 8.166   8.503   -13.750 0.670 18.360  0 161 LEU 2 N   1 ? 
ATOM   3018 C CA  . LEU B 1 159 ? 8.017   9.954   -13.485 0.670 18.680  0 161 LEU 2 CA  1 ? 
ATOM   3019 C C   . LEU B 1 159 ? 9.418   10.553  -13.462 0.670 17.250  0 161 LEU 2 C   1 ? 
ATOM   3020 O O   . LEU B 1 159 ? 10.325  9.948   -12.817 0.670 18.070  0 161 LEU 2 O   1 ? 
ATOM   3021 C CB  . LEU B 1 159 ? 7.310   10.160  -12.142 0.670 20.140  0 161 LEU 2 CB  1 ? 
ATOM   3022 C CG  . LEU B 1 159 ? 5.801   9.955   -12.143 0.670 20.020  0 161 LEU 2 CG  1 ? 
ATOM   3023 C CD1 . LEU B 1 159 ? 5.305   9.738   -10.731 0.670 21.660  0 161 LEU 2 CD1 1 ? 
ATOM   3024 C CD2 . LEU B 1 159 ? 5.081   11.113  -12.789 0.670 19.640  0 161 LEU 2 CD2 1 ? 
ATOM   3025 N N   . LEU B 1 160 ? 9.619   11.630  -14.214 0.670 18.190  0 162 LEU 2 N   1 ? 
ATOM   3026 C CA  . LEU B 1 160 ? 10.808  12.505  -14.061 0.670 18.510  0 162 LEU 2 CA  1 ? 
ATOM   3027 C C   . LEU B 1 160 ? 10.652  13.270  -12.745 0.670 18.860  0 162 LEU 2 C   1 ? 
ATOM   3028 O O   . LEU B 1 160 ? 9.541   13.788  -12.475 0.670 18.070  0 162 LEU 2 O   1 ? 
ATOM   3029 C CB  . LEU B 1 160 ? 10.938  13.462  -15.244 0.670 18.480  0 162 LEU 2 CB  1 ? 
ATOM   3030 C CG  . LEU B 1 160 ? 12.110  14.448  -15.159 0.670 19.310  0 162 LEU 2 CG  1 ? 
ATOM   3031 C CD1 . LEU B 1 160 ? 13.442  13.737  -15.308 0.670 20.600  0 162 LEU 2 CD1 1 ? 
ATOM   3032 C CD2 . LEU B 1 160 ? 11.967  15.531  -16.205 0.670 20.580  0 162 LEU 2 CD2 1 ? 
ATOM   3033 N N   . LEU B 1 161 ? 11.710  13.299  -11.948 0.670 18.050  0 163 LEU 2 N   1 ? 
ATOM   3034 C CA  . LEU B 1 161 ? 11.766  14.046  -10.667 0.670 20.800  0 163 LEU 2 CA  1 ? 
ATOM   3035 C C   . LEU B 1 161 ? 12.689  15.254  -10.804 0.670 22.150  0 163 LEU 2 C   1 ? 
ATOM   3036 O O   . LEU B 1 161 ? 13.577  15.231  -11.653 0.670 21.930  0 163 LEU 2 O   1 ? 
ATOM   3037 C CB  . LEU B 1 161 ? 12.331  13.153  -9.573  0.670 20.120  0 163 LEU 2 CB  1 ? 
ATOM   3038 C CG  . LEU B 1 161 ? 11.725  11.771  -9.417  0.670 20.930  0 163 LEU 2 CG  1 ? 
ATOM   3039 C CD1 . LEU B 1 161 ? 12.464  11.066  -8.302  0.670 21.820  0 163 LEU 2 CD1 1 ? 
ATOM   3040 C CD2 . LEU B 1 161 ? 10.220  11.854  -9.128  0.670 22.540  0 163 LEU 2 CD2 1 ? 
ATOM   3041 N N   . GLU B 1 162 ? 12.554  16.216  -9.898  0.670 25.860  0 164 GLU 2 N   1 ? 
ATOM   3042 C CA  . GLU B 1 162 ? 13.586  17.263  -9.641  0.670 30.980  0 164 GLU 2 CA  1 ? 
ATOM   3043 C C   . GLU B 1 162 ? 14.935  16.588  -9.378  0.670 30.670  0 164 GLU 2 C   1 ? 
ATOM   3044 O O   . GLU B 1 162 ? 14.947  15.537  -8.713  0.670 31.930  0 164 GLU 2 O   1 ? 
ATOM   3045 C CB  . GLU B 1 162 ? 13.141  18.150  -8.471  0.670 34.630  0 164 GLU 2 CB  1 ? 
ATOM   3046 C CG  . GLU B 1 162 ? 12.128  19.209  -8.881  0.670 42.310  0 164 GLU 2 CG  1 ? 
ATOM   3047 C CD  . GLU B 1 162 ? 11.788  20.279  -7.850  0.670 46.130  0 164 GLU 2 CD  1 ? 
ATOM   3048 O OE1 . GLU B 1 162 ? 12.704  20.698  -7.086  0.670 47.770  0 164 GLU 2 OE1 1 ? 
ATOM   3049 O OE2 . GLU B 1 162 ? 10.592  20.674  -7.801  0.670 48.810  0 164 GLU 2 OE2 1 ? 
ATOM   3050 N N   . GLY B 1 163 ? 16.030  17.131  -9.909  0.670 34.100  0 165 GLY 2 N   1 ? 
ATOM   3051 C CA  . GLY B 1 163 ? 17.391  16.633  -9.625  0.670 36.470  0 165 GLY 2 CA  1 ? 
ATOM   3052 C C   . GLY B 1 163 ? 17.831  15.469  -10.517 0.670 37.340  0 165 GLY 2 C   1 ? 
ATOM   3053 O O   . GLY B 1 163 ? 18.645  14.620  -10.047 0.670 35.260  0 165 GLY 2 O   1 ? 
ATOM   3054 N N   . ASN B 1 164 ? 17.364  15.426  -11.759 0.670 35.740  0 166 ASN 2 N   1 ? 
ATOM   3055 C CA  . ASN B 1 164 ? 17.901  14.499  -12.804 0.670 41.140  0 166 ASN 2 CA  1 ? 
ATOM   3056 C C   . ASN B 1 164 ? 17.724  13.035  -12.369 0.670 35.540  0 166 ASN 2 C   1 ? 
ATOM   3057 O O   . ASN B 1 164 ? 18.700  12.259  -12.491 0.670 32.350  0 166 ASN 2 O   1 ? 
ATOM   3058 C CB  . ASN B 1 164 ? 19.398  14.739  -13.078 0.670 42.150  0 166 ASN 2 CB  1 ? 
ATOM   3059 C CG  . ASN B 1 164 ? 19.706  16.103  -13.656 0.670 42.750  0 166 ASN 2 CG  1 ? 
ATOM   3060 O OD1 . ASN B 1 164 ? 18.813  16.787  -14.147 0.670 43.770  0 166 ASN 2 OD1 1 ? 
ATOM   3061 N ND2 . ASN B 1 164 ? 20.977  16.483  -13.639 0.670 36.670  0 166 ASN 2 ND2 1 ? 
ATOM   3062 N N   . ALA B 1 165 ? 16.566  12.683  -11.810 0.670 30.460  0 167 ALA 2 N   1 ? 
ATOM   3063 C CA  . ALA B 1 165 ? 16.267  11.295  -11.402 0.670 29.280  0 167 ALA 2 CA  1 ? 
ATOM   3064 C C   . ALA B 1 165 ? 14.905  10.883  -11.974 0.670 27.140  0 167 ALA 2 C   1 ? 
ATOM   3065 O O   . ALA B 1 165 ? 14.083  11.753  -12.312 0.670 24.320  0 167 ALA 2 O   1 ? 
ATOM   3066 C CB  . ALA B 1 165 ? 16.353  11.139  -9.902  0.670 30.360  0 167 ALA 2 CB  1 ? 
ATOM   3067 N N   . HIS B 1 166 ? 14.732  9.584   -12.198 0.670 25.180  0 168 HIS 2 N   1 ? 
ATOM   3068 C CA  . HIS B 1 166 ? 13.447  8.980   -12.601 0.670 22.060  0 168 HIS 2 CA  1 ? 
ATOM   3069 C C   . HIS B 1 166 ? 12.961  8.127   -11.438 0.670 21.370  0 168 HIS 2 C   1 ? 
ATOM   3070 O O   . HIS B 1 166 ? 13.809  7.616   -10.657 0.670 23.110  0 168 HIS 2 O   1 ? 
ATOM   3071 C CB  . HIS B 1 166 ? 13.589  8.186   -13.903 0.670 21.260  0 168 HIS 2 CB  1 ? 
ATOM   3072 C CG  . HIS B 1 166 ? 13.583  9.068   -15.090 0.670 22.580  0 168 HIS 2 CG  1 ? 
ATOM   3073 N ND1 . HIS B 1 166 ? 14.745  9.495   -15.688 0.670 23.240  0 168 HIS 2 ND1 1 ? 
ATOM   3074 C CD2 . HIS B 1 166 ? 12.563  9.631   -15.773 0.670 22.960  0 168 HIS 2 CD2 1 ? 
ATOM   3075 C CE1 . HIS B 1 166 ? 14.438  10.277  -16.710 0.670 24.070  0 168 HIS 2 CE1 1 ? 
ATOM   3076 N NE2 . HIS B 1 166 ? 13.103  10.381  -16.781 0.670 22.740  0 168 HIS 2 NE2 1 ? 
ATOM   3077 N N   . TYR B 1 167 ? 11.646  8.020   -11.328 0.670 20.370  0 169 TYR 2 N   1 ? 
ATOM   3078 C CA  . TYR B 1 167 ? 10.907  7.202   -10.344 0.670 18.890  0 169 TYR 2 CA  1 ? 
ATOM   3079 C C   . TYR B 1 167 ? 10.031  6.253   -11.152 0.670 19.730  0 169 TYR 2 C   1 ? 
ATOM   3080 O O   . TYR B 1 167 ? 9.091   6.752   -11.833 0.670 16.220  0 169 TYR 2 O   1 ? 
ATOM   3081 C CB  . TYR B 1 167 ? 10.108  8.157   -9.474  0.670 18.630  0 169 TYR 2 CB  1 ? 
ATOM   3082 C CG  . TYR B 1 167 ? 9.202   7.544   -8.447  0.670 19.610  0 169 TYR 2 CG  1 ? 
ATOM   3083 C CD1 . TYR B 1 167 ? 9.680   6.654   -7.499  0.670 18.720  0 169 TYR 2 CD1 1 ? 
ATOM   3084 C CD2 . TYR B 1 167 ? 7.879   7.932   -8.372  0.670 18.470  0 169 TYR 2 CD2 1 ? 
ATOM   3085 C CE1 . TYR B 1 167 ? 8.865   6.162   -6.504  0.670 19.320  0 169 TYR 2 CE1 1 ? 
ATOM   3086 C CE2 . TYR B 1 167 ? 7.051   7.439   -7.392  0.670 18.660  0 169 TYR 2 CE2 1 ? 
ATOM   3087 C CZ  . TYR B 1 167 ? 7.541   6.561   -6.454  0.670 18.310  0 169 TYR 2 CZ  1 ? 
ATOM   3088 O OH  . TYR B 1 167 ? 6.704   6.107   -5.494  0.670 18.000  0 169 TYR 2 OH  1 ? 
ATOM   3089 N N   . ARG B 1 168 ? 10.399  4.965   -11.147 0.670 18.890  0 170 ARG 2 N   1 ? 
ATOM   3090 C CA  . ARG B 1 168 ? 9.878   3.929   -12.060 0.670 21.060  0 170 ARG 2 CA  1 ? 
ATOM   3091 C C   . ARG B 1 168 ? 8.561   3.370   -11.526 0.670 19.060  0 170 ARG 2 C   1 ? 
ATOM   3092 O O   . ARG B 1 168 ? 8.386   3.220   -10.297 0.670 20.640  0 170 ARG 2 O   1 ? 
ATOM   3093 C CB  . ARG B 1 168 ? 10.909  2.819   -12.247 0.670 26.900  0 170 ARG 2 CB  1 ? 
ATOM   3094 C CG  . ARG B 1 168 ? 11.986  3.100   -13.282 0.670 33.670  0 170 ARG 2 CG  1 ? 
ATOM   3095 C CD  . ARG B 1 168 ? 11.662  2.436   -14.625 0.670 48.160  0 170 ARG 2 CD  1 ? 
ATOM   3096 N NE  . ARG B 1 168 ? 11.383  0.990   -14.519 0.670 56.570  0 170 ARG 2 NE  1 ? 
ATOM   3097 C CZ  . ARG B 1 168 ? 10.200  0.382   -14.726 0.670 58.510  0 170 ARG 2 CZ  1 ? 
ATOM   3098 N NH1 . ARG B 1 168 ? 9.121   1.063   -15.085 0.670 53.150  0 170 ARG 2 NH1 1 ? 
ATOM   3099 N NH2 . ARG B 1 168 ? 10.109  -0.933  -14.574 0.670 62.850  0 170 ARG 2 NH2 1 ? 
ATOM   3100 N N   . CYS B 1 169 ? 7.650   3.048   -12.430 0.670 16.550  0 171 CYS 2 N   1 ? 
ATOM   3101 C CA  . CYS B 1 169 ? 6.309   2.523   -12.097 0.670 17.380  0 171 CYS 2 CA  1 ? 
ATOM   3102 C C   . CYS B 1 169 ? 5.893   1.594   -13.231 0.670 18.450  0 171 CYS 2 C   1 ? 
ATOM   3103 O O   . CYS B 1 169 ? 6.046   2.019   -14.426 0.670 16.610  0 171 CYS 2 O   1 ? 
ATOM   3104 C CB  . CYS B 1 169 ? 5.337   3.681   -11.879 0.670 17.730  0 171 CYS 2 CB  1 ? 
ATOM   3105 S SG  . CYS B 1 169 ? 3.616   3.199   -11.617 0.670 18.140  0 171 CYS 2 SG  1 ? 
ATOM   3106 N N   . ASP B 1 170 ? 5.413   0.403   -12.864 0.670 18.000  0 172 ASP 2 N   1 ? 
ATOM   3107 C CA  . ASP B 1 170 ? 4.788   -0.567  -13.800 0.670 19.500  0 172 ASP 2 CA  1 ? 
ATOM   3108 C C   . ASP B 1 170 ? 3.271   -0.432  -13.714 0.670 19.170  0 172 ASP 2 C   1 ? 
ATOM   3109 O O   . ASP B 1 170 ? 2.732   -0.401  -12.589 0.670 19.570  0 172 ASP 2 O   1 ? 
ATOM   3110 C CB  . ASP B 1 170 ? 5.198   -2.001  -13.487 0.670 22.120  0 172 ASP 2 CB  1 ? 
ATOM   3111 C CG  . ASP B 1 170 ? 6.632   -2.319  -13.862 0.670 25.790  0 172 ASP 2 CG  1 ? 
ATOM   3112 O OD1 . ASP B 1 170 ? 7.334   -1.419  -14.384 0.670 27.920  0 172 ASP 2 OD1 1 ? 
ATOM   3113 O OD2 . ASP B 1 170 ? 7.026   -3.457  -13.629 0.670 31.600  0 172 ASP 2 OD2 1 ? 
ATOM   3114 N N   . PHE B 1 171 ? 2.621   -0.393  -14.878 0.670 19.260  0 173 PHE 2 N   1 ? 
ATOM   3115 C CA  . PHE B 1 171 ? 1.150   -0.352  -15.031 0.670 20.390  0 173 PHE 2 CA  1 ? 
ATOM   3116 C C   . PHE B 1 171 ? 0.675   -1.688  -15.589 0.670 18.720  0 173 PHE 2 C   1 ? 
ATOM   3117 O O   . PHE B 1 171 ? 1.252   -2.164  -16.577 0.670 18.830  0 173 PHE 2 O   1 ? 
ATOM   3118 C CB  . PHE B 1 171 ? 0.694   0.696   -16.048 0.670 22.020  0 173 PHE 2 CB  1 ? 
ATOM   3119 C CG  . PHE B 1 171 ? 0.824   2.147   -15.678 0.670 26.300  0 173 PHE 2 CG  1 ? 
ATOM   3120 C CD1 . PHE B 1 171 ? 1.933   2.628   -15.002 0.670 26.960  0 173 PHE 2 CD1 1 ? 
ATOM   3121 C CD2 . PHE B 1 171 ? -0.120  3.059   -16.123 0.670 28.770  0 173 PHE 2 CD2 1 ? 
ATOM   3122 C CE1 . PHE B 1 171 ? 2.062   3.984   -14.730 0.670 30.020  0 173 PHE 2 CE1 1 ? 
ATOM   3123 C CE2 . PHE B 1 171 ? 0.003   4.406   -15.828 0.670 28.640  0 173 PHE 2 CE2 1 ? 
ATOM   3124 C CZ  . PHE B 1 171 ? 1.096   4.864   -15.139 0.670 28.700  0 173 PHE 2 CZ  1 ? 
ATOM   3125 N N   . ARG B 1 172 ? -0.399  -2.220  -15.021 0.670 18.860  0 174 ARG 2 N   1 ? 
ATOM   3126 C CA  . ARG B 1 172 ? -1.200  -3.277  -15.677 0.670 19.310  0 174 ARG 2 CA  1 ? 
ATOM   3127 C C   . ARG B 1 172 ? -2.668  -2.850  -15.638 0.670 17.770  0 174 ARG 2 C   1 ? 
ATOM   3128 O O   . ARG B 1 172 ? -3.185  -2.594  -14.556 0.670 17.670  0 174 ARG 2 O   1 ? 
ATOM   3129 C CB  . ARG B 1 172 ? -1.009  -4.649  -15.026 0.670 21.100  0 174 ARG 2 CB  1 ? 
ATOM   3130 C CG  . ARG B 1 172 ? -1.849  -5.720  -15.717 0.670 23.620  0 174 ARG 2 CG  1 ? 
ATOM   3131 C CD  . ARG B 1 172 ? -1.372  -7.137  -15.478 0.670 26.640  0 174 ARG 2 CD  1 ? 
ATOM   3132 N NE  . ARG B 1 172 ? -0.090  -7.328  -16.120 0.670 28.290  0 174 ARG 2 NE  1 ? 
ATOM   3133 C CZ  . ARG B 1 172 ? 0.812   -8.221  -15.742 0.670 30.180  0 174 ARG 2 CZ  1 ? 
ATOM   3134 N NH1 . ARG B 1 172 ? 0.566   -9.042  -14.736 0.670 29.670  0 174 ARG 2 NH1 1 ? 
ATOM   3135 N NH2 . ARG B 1 172 ? 1.951   -8.305  -16.385 0.670 28.620  0 174 ARG 2 NH2 1 ? 
ATOM   3136 N N   . THR B 1 173 ? -3.335  -2.824  -16.782 0.670 17.250  0 175 THR 2 N   1 ? 
ATOM   3137 C CA  . THR B 1 173 ? -4.782  -2.476  -16.874 0.670 17.410  0 175 THR 2 CA  1 ? 
ATOM   3138 C C   . THR B 1 173 ? -5.521  -3.631  -17.531 0.670 18.140  0 175 THR 2 C   1 ? 
ATOM   3139 O O   . THR B 1 173 ? -5.029  -4.107  -18.562 0.670 19.360  0 175 THR 2 O   1 ? 
ATOM   3140 C CB  . THR B 1 173 ? -5.040  -1.236  -17.742 0.670 17.400  0 175 THR 2 CB  1 ? 
ATOM   3141 O OG1 . THR B 1 173 ? -4.140  -0.210  -17.344 0.670 17.270  0 175 THR 2 OG1 1 ? 
ATOM   3142 C CG2 . THR B 1 173 ? -6.461  -0.733  -17.651 0.670 17.740  0 175 THR 2 CG2 1 ? 
ATOM   3143 N N   . THR B 1 174 ? -6.668  -4.017  -16.986 0.670 17.680  0 176 THR 2 N   1 ? 
ATOM   3144 C CA  . THR B 1 174 ? -7.618  -4.914  -17.658 0.670 18.690  0 176 THR 2 CA  1 ? 
ATOM   3145 C C   . THR B 1 174 ? -8.787  -4.069  -18.169 0.670 19.740  0 176 THR 2 C   1 ? 
ATOM   3146 O O   . THR B 1 174 ? -9.289  -3.188  -17.438 0.670 17.500  0 176 THR 2 O   1 ? 
ATOM   3147 C CB  . THR B 1 174 ? -8.026  -6.090  -16.766 0.670 20.250  0 176 THR 2 CB  1 ? 
ATOM   3148 O OG1 . THR B 1 174 ? -8.753  -5.583  -15.648 0.670 23.730  0 176 THR 2 OG1 1 ? 
ATOM   3149 C CG2 . THR B 1 174 ? -6.829  -6.876  -16.289 0.670 21.340  0 176 THR 2 CG2 1 ? 
ATOM   3150 N N   . TYR B 1 175 ? -9.229  -4.369  -19.378 0.670 19.800  0 177 TYR 2 N   1 ? 
ATOM   3151 C CA  . TYR B 1 175 ? -10.321 -3.639  -20.070 0.670 20.420  0 177 TYR 2 CA  1 ? 
ATOM   3152 C C   . TYR B 1 175 ? -11.469 -4.619  -20.344 0.670 20.890  0 177 TYR 2 C   1 ? 
ATOM   3153 O O   . TYR B 1 175 ? -11.192 -5.674  -20.946 0.670 20.480  0 177 TYR 2 O   1 ? 
ATOM   3154 C CB  . TYR B 1 175 ? -9.761  -3.037  -21.351 0.670 19.160  0 177 TYR 2 CB  1 ? 
ATOM   3155 C CG  . TYR B 1 175 ? -8.598  -2.073  -21.217 0.670 18.870  0 177 TYR 2 CG  1 ? 
ATOM   3156 C CD1 . TYR B 1 175 ? -8.810  -0.752  -20.870 0.670 18.520  0 177 TYR 2 CD1 1 ? 
ATOM   3157 C CD2 . TYR B 1 175 ? -7.294  -2.438  -21.526 0.670 19.200  0 177 TYR 2 CD2 1 ? 
ATOM   3158 C CE1 . TYR B 1 175 ? -7.778  0.166   -20.826 0.670 16.650  0 177 TYR 2 CE1 1 ? 
ATOM   3159 C CE2 . TYR B 1 175 ? -6.233  -1.536  -21.468 0.670 18.730  0 177 TYR 2 CE2 1 ? 
ATOM   3160 C CZ  . TYR B 1 175 ? -6.480  -0.216  -21.114 0.670 19.260  0 177 TYR 2 CZ  1 ? 
ATOM   3161 O OH  . TYR B 1 175 ? -5.498  0.737   -21.051 0.670 17.630  0 177 TYR 2 OH  1 ? 
ATOM   3162 N N   . LYS B 1 176 ? -12.704 -4.283  -19.954 0.670 19.990  0 178 LYS 2 N   1 ? 
ATOM   3163 C CA  . LYS B 1 176 ? -13.882 -5.165  -20.163 0.670 23.060  0 178 LYS 2 CA  1 ? 
ATOM   3164 C C   . LYS B 1 176 ? -15.061 -4.380  -20.736 0.670 20.050  0 178 LYS 2 C   1 ? 
ATOM   3165 O O   . LYS B 1 176 ? -15.607 -3.483  -20.025 0.670 17.800  0 178 LYS 2 O   1 ? 
ATOM   3166 C CB  . LYS B 1 176 ? -14.321 -5.818  -18.850 0.670 28.350  0 178 LYS 2 CB  1 ? 
ATOM   3167 C CG  . LYS B 1 176 ? -13.354 -6.841  -18.292 0.670 37.120  0 178 LYS 2 CG  1 ? 
ATOM   3168 C CD  . LYS B 1 176 ? -13.783 -7.374  -16.932 0.670 41.430  0 178 LYS 2 CD  1 ? 
ATOM   3169 C CE  . LYS B 1 176 ? -12.687 -8.149  -16.227 0.670 47.130  0 178 LYS 2 CE  1 ? 
ATOM   3170 N NZ  . LYS B 1 176 ? -13.236 -8.985  -15.130 0.670 51.050  0 178 LYS 2 NZ  1 ? 
ATOM   3171 N N   . ALA B 1 177 ? -15.470 -4.753  -21.954 0.670 20.530  0 179 ALA 2 N   1 ? 
ATOM   3172 C CA  . ALA B 1 177 ? -16.733 -4.327  -22.597 0.670 21.440  0 179 ALA 2 CA  1 ? 
ATOM   3173 C C   . ALA B 1 177 ? -17.907 -4.791  -21.727 0.670 23.940  0 179 ALA 2 C   1 ? 
ATOM   3174 O O   . ALA B 1 177 ? -17.845 -5.928  -21.194 0.670 22.810  0 179 ALA 2 O   1 ? 
ATOM   3175 C CB  . ALA B 1 177 ? -16.816 -4.908  -23.986 0.670 22.800  0 179 ALA 2 CB  1 ? 
ATOM   3176 N N   . LYS B 1 178 ? -18.933 -3.955  -21.587 0.670 24.540  0 180 LYS 2 N   1 ? 
ATOM   3177 C CA  . LYS B 1 178 ? -20.172 -4.289  -20.836 0.670 29.320  0 180 LYS 2 CA  1 ? 
ATOM   3178 C C   . LYS B 1 178 ? -21.025 -5.260  -21.658 0.670 30.360  0 180 LYS 2 C   1 ? 
ATOM   3179 O O   . LYS B 1 178 ? -21.757 -6.041  -21.051 0.670 33.890  0 180 LYS 2 O   1 ? 
ATOM   3180 C CB  . LYS B 1 178 ? -20.925 -3.005  -20.494 0.670 33.030  0 180 LYS 2 CB  1 ? 
ATOM   3181 C CG  . LYS B 1 178 ? -20.246 -2.223  -19.378 0.670 37.140  0 180 LYS 2 CG  1 ? 
ATOM   3182 C CD  . LYS B 1 178 ? -20.632 -0.774  -19.283 0.670 41.630  0 180 LYS 2 CD  1 ? 
ATOM   3183 C CE  . LYS B 1 178 ? -19.995 -0.127  -18.073 0.670 44.740  0 180 LYS 2 CE  1 ? 
ATOM   3184 N NZ  . LYS B 1 178 ? -20.209 1.337   -18.057 0.670 44.510  0 180 LYS 2 NZ  1 ? 
ATOM   3185 N N   . GLU B 1 179 ? -20.920 -5.192  -22.981 0.670 34.150  0 181 GLU 2 N   1 ? 
ATOM   3186 C CA  . GLU B 1 179 ? -21.633 -6.090  -23.916 0.670 41.870  0 181 GLU 2 CA  1 ? 
ATOM   3187 C C   . GLU B 1 179 ? -20.846 -7.388  -24.026 0.670 44.650  0 181 GLU 2 C   1 ? 
ATOM   3188 O O   . GLU B 1 179 ? -19.680 -7.360  -24.425 0.670 42.170  0 181 GLU 2 O   1 ? 
ATOM   3189 C CB  . GLU B 1 179 ? -21.821 -5.469  -25.300 0.670 48.560  0 181 GLU 2 CB  1 ? 
ATOM   3190 C CG  . GLU B 1 179 ? -23.022 -6.023  -26.042 0.670 54.640  0 181 GLU 2 CG  1 ? 
ATOM   3191 C CD  . GLU B 1 179 ? -24.320 -5.335  -25.652 0.670 59.720  0 181 GLU 2 CD  1 ? 
ATOM   3192 O OE1 . GLU B 1 179 ? -24.514 -4.151  -26.040 0.670 62.400  0 181 GLU 2 OE1 1 ? 
ATOM   3193 O OE2 . GLU B 1 179 ? -25.109 -5.971  -24.935 0.670 61.550  0 181 GLU 2 OE2 1 ? 
ATOM   3194 N N   . LYS B 1 180 ? -21.478 -8.471  -23.592 0.670 56.250  0 182 LYS 2 N   1 ? 
ATOM   3195 C CA  . LYS B 1 180 ? -21.237 -9.851  -24.071 0.670 58.030  0 182 LYS 2 CA  1 ? 
ATOM   3196 C C   . LYS B 1 180 ? -21.012 -9.794  -25.587 0.670 52.230  0 182 LYS 2 C   1 ? 
ATOM   3197 O O   . LYS B 1 180 ? -21.913 -9.281  -26.293 0.670 54.310  0 182 LYS 2 O   1 ? 
ATOM   3198 C CB  . LYS B 1 180 ? -22.475 -10.684 -23.714 0.670 65.670  0 182 LYS 2 CB  1 ? 
ATOM   3199 C CG  . LYS B 1 180 ? -22.268 -12.183 -23.602 0.670 70.210  0 182 LYS 2 CG  1 ? 
ATOM   3200 C CD  . LYS B 1 180 ? -23.549 -12.960 -23.826 0.670 72.110  0 182 LYS 2 CD  1 ? 
ATOM   3201 C CE  . LYS B 1 180 ? -23.453 -14.397 -23.372 0.670 70.770  0 182 LYS 2 CE  1 ? 
ATOM   3202 N NZ  . LYS B 1 180 ? -22.110 -14.965 -23.642 0.670 71.230  0 182 LYS 2 NZ  1 ? 
ATOM   3203 N N   . GLY B 1 181 ? -19.845 -10.250 -26.059 0.670 47.300  0 183 GLY 2 N   1 ? 
ATOM   3204 C CA  . GLY B 1 181 ? -19.609 -10.590 -27.476 0.670 42.630  0 183 GLY 2 CA  1 ? 
ATOM   3205 C C   . GLY B 1 181 ? -19.008 -9.470  -28.316 0.670 40.330  0 183 GLY 2 C   1 ? 
ATOM   3206 O O   . GLY B 1 181 ? -19.017 -9.619  -29.544 0.670 43.960  0 183 GLY 2 O   1 ? 
ATOM   3207 N N   . VAL B 1 182 ? -18.474 -8.393  -27.733 0.670 34.400  0 184 VAL 2 N   1 ? 
ATOM   3208 C CA  . VAL B 1 182 ? -17.499 -7.535  -28.469 0.670 29.590  0 184 VAL 2 CA  1 ? 
ATOM   3209 C C   . VAL B 1 182 ? -16.235 -8.376  -28.641 0.670 27.500  0 184 VAL 2 C   1 ? 
ATOM   3210 O O   . VAL B 1 182 ? -15.737 -8.857  -27.621 0.670 24.880  0 184 VAL 2 O   1 ? 
ATOM   3211 C CB  . VAL B 1 182 ? -17.178 -6.223  -27.734 0.670 31.650  0 184 VAL 2 CB  1 ? 
ATOM   3212 C CG1 . VAL B 1 182 ? -16.059 -5.455  -28.427 0.670 30.720  0 184 VAL 2 CG1 1 ? 
ATOM   3213 C CG2 . VAL B 1 182 ? -18.413 -5.362  -27.564 0.670 32.480  0 184 VAL 2 CG2 1 ? 
ATOM   3214 N N   . LYS B 1 183 ? -15.750 -8.556  -29.877 0.670 25.250  0 185 LYS 2 N   1 ? 
ATOM   3215 C CA  . LYS B 1 183 ? -14.554 -9.377  -30.191 0.670 26.220  0 185 LYS 2 CA  1 ? 
ATOM   3216 C C   . LYS B 1 183 ? -13.284 -8.721  -29.656 0.670 25.500  0 185 LYS 2 C   1 ? 
ATOM   3217 O O   . LYS B 1 183 ? -13.097 -7.493  -29.813 0.670 25.920  0 185 LYS 2 O   1 ? 
ATOM   3218 C CB  . LYS B 1 183 ? -14.449 -9.621  -31.698 0.670 30.610  0 185 LYS 2 CB  1 ? 
ATOM   3219 C CG  . LYS B 1 183 ? -15.496 -10.585 -32.239 0.670 34.150  0 185 LYS 2 CG  1 ? 
ATOM   3220 C CD  . LYS B 1 183 ? -15.082 -12.048 -32.130 0.670 39.160  0 185 LYS 2 CD  1 ? 
ATOM   3221 C CE  . LYS B 1 183 ? -13.877 -12.407 -32.985 0.670 40.620  0 185 LYS 2 CE  1 ? 
ATOM   3222 N NZ  . LYS B 1 183 ? -13.513 -13.844 -32.875 0.670 44.520  0 185 LYS 2 NZ  1 ? 
ATOM   3223 N N   . LEU B 1 184 ? -12.431 -9.537  -29.049 0.670 24.140  0 186 LEU 2 N   1 ? 
ATOM   3224 C CA  . LEU B 1 184 ? -11.098 -9.122  -28.576 0.670 23.660  0 186 LEU 2 CA  1 ? 
ATOM   3225 C C   . LEU B 1 184 ? -10.205 -8.839  -29.779 0.670 24.140  0 186 LEU 2 C   1 ? 
ATOM   3226 O O   . LEU B 1 184 ? -10.342 -9.452  -30.842 0.670 19.410  0 186 LEU 2 O   1 ? 
ATOM   3227 C CB  . LEU B 1 184 ? -10.540 -10.215 -27.670 0.670 24.140  0 186 LEU 2 CB  1 ? 
ATOM   3228 C CG  . LEU B 1 184 ? -11.329 -10.444 -26.387 0.670 25.760  0 186 LEU 2 CG  1 ? 
ATOM   3229 C CD1 . LEU B 1 184 ? -10.840 -11.690 -25.673 0.670 26.960  0 186 LEU 2 CD1 1 ? 
ATOM   3230 C CD2 . LEU B 1 184 ? -11.218 -9.245  -25.467 0.670 28.220  0 186 LEU 2 CD2 1 ? 
ATOM   3231 N N   . PRO B 1 185 ? -9.326  -7.818  -29.664 0.670 21.790  0 187 PRO 2 N   1 ? 
ATOM   3232 C CA  . PRO B 1 185 ? -8.377  -7.498  -30.704 0.670 21.820  0 187 PRO 2 CA  1 ? 
ATOM   3233 C C   . PRO B 1 185 ? -7.166  -8.426  -30.635 0.670 21.400  0 187 PRO 2 C   1 ? 
ATOM   3234 O O   . PRO B 1 185 ? -6.956  -9.078  -29.620 0.670 23.120  0 187 PRO 2 O   1 ? 
ATOM   3235 C CB  . PRO B 1 185 ? -7.961  -6.053  -30.358 0.670 21.250  0 187 PRO 2 CB  1 ? 
ATOM   3236 C CG  . PRO B 1 185 ? -8.046  -6.022  -28.868 0.670 20.410  0 187 PRO 2 CG  1 ? 
ATOM   3237 C CD  . PRO B 1 185 ? -9.242  -6.871  -28.533 0.670 22.230  0 187 PRO 2 CD  1 ? 
ATOM   3238 N N   . GLY B 1 186 ? -6.387  -8.435  -31.707 0.670 22.710  0 188 GLY 2 N   1 ? 
ATOM   3239 C CA  . GLY B 1 186 ? -5.030  -8.997  -31.686 0.670 22.390  0 188 GLY 2 CA  1 ? 
ATOM   3240 C C   . GLY B 1 186 ? -4.129  -8.112  -30.835 0.670 21.650  0 188 GLY 2 C   1 ? 
ATOM   3241 O O   . GLY B 1 186 ? -4.510  -6.960  -30.512 0.670 22.930  0 188 GLY 2 O   1 ? 
ATOM   3242 N N   . ALA B 1 187 ? -2.950  -8.608  -30.531 0.670 19.960  0 189 ALA 2 N   1 ? 
ATOM   3243 C CA  . ALA B 1 187 ? -1.940  -7.895  -29.734 0.670 20.240  0 189 ALA 2 CA  1 ? 
ATOM   3244 C C   . ALA B 1 187 ? -1.478  -6.706  -30.568 0.670 20.250  0 189 ALA 2 C   1 ? 
ATOM   3245 O O   . ALA B 1 187 ? -1.428  -6.816  -31.823 0.670 18.680  0 189 ALA 2 O   1 ? 
ATOM   3246 C CB  . ALA B 1 187 ? -0.842  -8.845  -29.352 0.670 19.520  0 189 ALA 2 CB  1 ? 
ATOM   3247 N N   . HIS B 1 188 ? -1.225  -5.584  -29.899 0.670 18.920  0 190 HIS 2 N   1 ? 
ATOM   3248 C CA  . HIS B 1 188 ? -0.805  -4.311  -30.526 0.670 18.580  0 190 HIS 2 CA  1 ? 
ATOM   3249 C C   . HIS B 1 188 ? -0.187  -3.392  -29.456 0.670 17.880  0 190 HIS 2 C   1 ? 
ATOM   3250 O O   . HIS B 1 188 ? 0.062   -3.845  -28.295 0.670 17.140  0 190 HIS 2 O   1 ? 
ATOM   3251 C CB  . HIS B 1 188 ? -1.960  -3.666  -31.305 0.670 18.810  0 190 HIS 2 CB  1 ? 
ATOM   3252 C CG  . HIS B 1 188 ? -3.146  -3.248  -30.484 0.670 20.120  0 190 HIS 2 CG  1 ? 
ATOM   3253 N ND1 . HIS B 1 188 ? -4.130  -4.144  -30.095 0.670 19.020  0 190 HIS 2 ND1 1 ? 
ATOM   3254 C CD2 . HIS B 1 188 ? -3.506  -2.043  -29.974 0.670 18.870  0 190 HIS 2 CD2 1 ? 
ATOM   3255 C CE1 . HIS B 1 188 ? -5.070  -3.495  -29.410 0.670 20.070  0 190 HIS 2 CE1 1 ? 
ATOM   3256 N NE2 . HIS B 1 188 ? -4.707  -2.217  -29.318 0.670 17.630  0 190 HIS 2 NE2 1 ? 
ATOM   3257 N N   . PHE B 1 189 ? 0.163   -2.194  -29.873 0.670 18.650  0 191 PHE 2 N   1 ? 
ATOM   3258 C CA  . PHE B 1 189 ? 0.806   -1.165  -29.027 0.670 20.650  0 191 PHE 2 CA  1 ? 
ATOM   3259 C C   . PHE B 1 189 ? -0.011  0.117   -29.102 0.670 20.860  0 191 PHE 2 C   1 ? 
ATOM   3260 O O   . PHE B 1 189 ? -0.556  0.402   -30.175 0.670 22.210  0 191 PHE 2 O   1 ? 
ATOM   3261 C CB  . PHE B 1 189 ? 2.220   -0.875  -29.519 0.670 23.230  0 191 PHE 2 CB  1 ? 
ATOM   3262 C CG  . PHE B 1 189 ? 3.089   -2.100  -29.609 0.670 26.590  0 191 PHE 2 CG  1 ? 
ATOM   3263 C CD1 . PHE B 1 189 ? 3.787   -2.554  -28.505 0.670 28.440  0 191 PHE 2 CD1 1 ? 
ATOM   3264 C CD2 . PHE B 1 189 ? 3.151   -2.826  -30.784 0.670 30.770  0 191 PHE 2 CD2 1 ? 
ATOM   3265 C CE1 . PHE B 1 189 ? 4.556   -3.704  -28.582 0.670 32.400  0 191 PHE 2 CE1 1 ? 
ATOM   3266 C CE2 . PHE B 1 189 ? 3.930   -3.967  -30.867 0.670 33.640  0 191 PHE 2 CE2 1 ? 
ATOM   3267 C CZ  . PHE B 1 189 ? 4.633   -4.403  -29.764 0.670 34.540  0 191 PHE 2 CZ  1 ? 
ATOM   3268 N N   . VAL B 1 190 ? -0.008  0.887   -28.020 0.670 19.760  0 192 VAL 2 N   1 ? 
ATOM   3269 C CA  . VAL B 1 190 ? -0.512  2.278   -27.999 0.670 18.690  0 192 VAL 2 CA  1 ? 
ATOM   3270 C C   . VAL B 1 190 ? 0.614   3.173   -27.468 0.670 19.560  0 192 VAL 2 C   1 ? 
ATOM   3271 O O   . VAL B 1 190 ? 0.978   3.048   -26.280 0.670 18.000  0 192 VAL 2 O   1 ? 
ATOM   3272 C CB  . VAL B 1 190 ? -1.791  2.380   -27.146 0.670 19.390  0 192 VAL 2 CB  1 ? 
ATOM   3273 C CG1 . VAL B 1 190 ? -2.416  3.776   -27.251 0.670 19.330  0 192 VAL 2 CG1 1 ? 
ATOM   3274 C CG2 . VAL B 1 190 ? -2.799  1.316   -27.518 0.670 18.710  0 192 VAL 2 CG2 1 ? 
ATOM   3275 N N   . ASP B 1 191 ? 1.122   4.061   -28.310 0.670 19.740  0 193 ASP 2 N   1 ? 
ATOM   3276 C CA  . ASP B 1 191 ? 2.045   5.134   -27.873 0.670 20.380  0 193 ASP 2 CA  1 ? 
ATOM   3277 C C   . ASP B 1 191 ? 1.200   6.232   -27.240 0.670 20.560  0 193 ASP 2 C   1 ? 
ATOM   3278 O O   . ASP B 1 191 ? 0.181   6.623   -27.834 0.670 18.780  0 193 ASP 2 O   1 ? 
ATOM   3279 C CB  . ASP B 1 191 ? 2.851   5.738   -29.014 0.670 22.450  0 193 ASP 2 CB  1 ? 
ATOM   3280 C CG  . ASP B 1 191 ? 3.800   4.753   -29.660 0.670 24.850  0 193 ASP 2 CG  1 ? 
ATOM   3281 O OD1 . ASP B 1 191 ? 4.220   3.779   -29.000 0.670 25.990  0 193 ASP 2 OD1 1 ? 
ATOM   3282 O OD2 . ASP B 1 191 ? 4.086   4.976   -30.846 0.670 29.660  0 193 ASP 2 OD2 1 ? 
ATOM   3283 N N   . HIS B 1 192 ? 1.609   6.708   -26.072 0.670 20.410  0 194 HIS 2 N   1 ? 
ATOM   3284 C CA  . HIS B 1 192 ? 0.818   7.722   -25.353 0.670 22.450  0 194 HIS 2 CA  1 ? 
ATOM   3285 C C   . HIS B 1 192 ? 1.746   8.667   -24.620 0.670 19.020  0 194 HIS 2 C   1 ? 
ATOM   3286 O O   . HIS B 1 192 ? 2.885   8.267   -24.249 0.670 18.120  0 194 HIS 2 O   1 ? 
ATOM   3287 C CB  . HIS B 1 192 ? -0.184  7.055   -24.421 0.670 26.150  0 194 HIS 2 CB  1 ? 
ATOM   3288 C CG  . HIS B 1 192 ? 0.441   6.562   -23.175 0.670 32.830  0 194 HIS 2 CG  1 ? 
ATOM   3289 N ND1 . HIS B 1 192 ? 1.100   5.347   -23.120 0.670 39.760  0 194 HIS 2 ND1 1 ? 
ATOM   3290 C CD2 . HIS B 1 192 ? 0.507   7.116   -21.947 0.670 34.730  0 194 HIS 2 CD2 1 ? 
ATOM   3291 C CE1 . HIS B 1 192 ? 1.547   5.178   -21.894 0.670 41.360  0 194 HIS 2 CE1 1 ? 
ATOM   3292 N NE2 . HIS B 1 192 ? 1.220   6.263   -21.172 0.670 39.040  0 194 HIS 2 NE2 1 ? 
ATOM   3293 N N   . CYS B 1 193 ? 1.256   9.888   -24.453 0.670 18.360  0 195 CYS 2 N   1 ? 
ATOM   3294 C CA  . CYS B 1 193 ? 1.965   10.920  -23.680 0.670 17.780  0 195 CYS 2 CA  1 ? 
ATOM   3295 C C   . CYS B 1 193 ? 0.903   11.778  -23.000 0.670 16.700  0 195 CYS 2 C   1 ? 
ATOM   3296 O O   . CYS B 1 193 ? -0.157  12.048  -23.590 0.670 15.940  0 195 CYS 2 O   1 ? 
ATOM   3297 C CB  . CYS B 1 193 ? 2.958   11.632  -24.605 0.670 22.750  0 195 CYS 2 CB  1 ? 
ATOM   3298 S SG  . CYS B 1 193 ? 3.460   13.295  -24.104 0.670 26.160  0 195 CYS 2 SG  1 ? 
ATOM   3299 N N   . ILE B 1 194 ? 1.135   12.107  -21.744 0.670 15.840  0 196 ILE 2 N   1 ? 
ATOM   3300 C CA  . ILE B 1 194 ? 0.141   12.871  -20.951 0.670 18.110  0 196 ILE 2 CA  1 ? 
ATOM   3301 C C   . ILE B 1 194 ? 0.873   14.076  -20.376 0.670 17.340  0 196 ILE 2 C   1 ? 
ATOM   3302 O O   . ILE B 1 194 ? 2.029   13.905  -19.954 0.670 16.850  0 196 ILE 2 O   1 ? 
ATOM   3303 C CB  . ILE B 1 194 ? -0.540  11.958  -19.913 0.670 17.580  0 196 ILE 2 CB  1 ? 
ATOM   3304 C CG1 . ILE B 1 194 ? -1.715  12.661  -19.237 0.670 19.320  0 196 ILE 2 CG1 1 ? 
ATOM   3305 C CG2 . ILE B 1 194 ? 0.467   11.408  -18.931 0.670 18.220  0 196 ILE 2 CG2 1 ? 
ATOM   3306 C CD1 . ILE B 1 194 ? -2.659  11.705  -18.514 0.670 18.890  0 196 ILE 2 CD1 1 ? 
ATOM   3307 N N   . GLU B 1 195 ? 0.234   15.239  -20.456 0.670 19.320  0 197 GLU 2 N   1 ? 
ATOM   3308 C CA  . GLU B 1 195 ? 0.836   16.546  -20.078 0.670 21.390  0 197 GLU 2 CA  1 ? 
ATOM   3309 C C   . GLU B 1 195 ? -0.137  17.335  -19.219 0.670 19.080  0 197 GLU 2 C   1 ? 
ATOM   3310 O O   . GLU B 1 195 ? -1.309  17.468  -19.626 0.670 18.590  0 197 GLU 2 O   1 ? 
ATOM   3311 C CB  . GLU B 1 195 ? 1.058   17.444  -21.291 0.670 26.260  0 197 GLU 2 CB  1 ? 
ATOM   3312 C CG  . GLU B 1 195 ? 2.283   17.134  -22.118 0.670 32.930  0 197 GLU 2 CG  1 ? 
ATOM   3313 C CD  . GLU B 1 195 ? 2.355   17.984  -23.384 0.670 33.000  0 197 GLU 2 CD  1 ? 
ATOM   3314 O OE1 . GLU B 1 195 ? 2.555   19.217  -23.249 0.670 33.820  0 197 GLU 2 OE1 1 ? 
ATOM   3315 O OE2 . GLU B 1 195 ? 2.119   17.428  -24.483 0.670 34.400  0 197 GLU 2 OE2 1 ? 
ATOM   3316 N N   . ILE B 1 196 ? 0.354   17.914  -18.128 0.670 17.470  0 198 ILE 2 N   1 ? 
ATOM   3317 C CA  . ILE B 1 196 ? -0.351  19.030  -17.453 0.670 18.120  0 198 ILE 2 CA  1 ? 
ATOM   3318 C C   . ILE B 1 196 ? -0.020  20.317  -18.218 0.670 18.550  0 198 ILE 2 C   1 ? 
ATOM   3319 O O   . ILE B 1 196 ? 1.151   20.706  -18.286 0.670 18.400  0 198 ILE 2 O   1 ? 
ATOM   3320 C CB  . ILE B 1 196 ? -0.018  19.097  -15.958 0.670 19.220  0 198 ILE 2 CB  1 ? 
ATOM   3321 C CG1 . ILE B 1 196 ? -0.540  17.843  -15.251 0.670 19.740  0 198 ILE 2 CG1 1 ? 
ATOM   3322 C CG2 . ILE B 1 196 ? -0.575  20.388  -15.379 0.670 19.010  0 198 ILE 2 CG2 1 ? 
ATOM   3323 C CD1 . ILE B 1 196 ? -0.213  17.762  -13.764 0.670 23.310  0 198 ILE 2 CD1 1 ? 
ATOM   3324 N N   . LEU B 1 197 ? -1.018  20.914  -18.841 0.670 18.820  0 199 LEU 2 N   1 ? 
ATOM   3325 C CA  . LEU B 1 197 ? -0.846  22.119  -19.695 0.670 20.570  0 199 LEU 2 CA  1 ? 
ATOM   3326 C C   . LEU B 1 197 ? -0.823  23.377  -18.819 0.670 20.130  0 199 LEU 2 C   1 ? 
ATOM   3327 O O   . LEU B 1 197 ? -0.182  24.353  -19.195 0.670 19.600  0 199 LEU 2 O   1 ? 
ATOM   3328 C CB  . LEU B 1 197 ? -2.028  22.200  -20.648 0.670 21.440  0 199 LEU 2 CB  1 ? 
ATOM   3329 C CG  . LEU B 1 197 ? -2.113  21.117  -21.721 0.670 20.980  0 199 LEU 2 CG  1 ? 
ATOM   3330 C CD1 . LEU B 1 197 ? -3.254  21.439  -22.669 0.670 21.650  0 199 LEU 2 CD1 1 ? 
ATOM   3331 C CD2 . LEU B 1 197 ? -0.818  20.955  -22.471 0.670 22.290  0 199 LEU 2 CD2 1 ? 
ATOM   3332 N N   . SER B 1 198 ? -1.579  23.381  -17.735 0.670 20.240  0 200 SER 2 N   1 ? 
ATOM   3333 C CA  . SER B 1 198 ? -1.603  24.507  -16.772 0.670 20.060  0 200 SER 2 CA  1 ? 
ATOM   3334 C C   . SER B 1 198 ? -2.113  24.022  -15.424 0.670 19.030  0 200 SER 2 C   1 ? 
ATOM   3335 O O   . SER B 1 198 ? -2.726  22.914  -15.354 0.670 19.320  0 200 SER 2 O   1 ? 
ATOM   3336 C CB  . SER B 1 198 ? -2.415  25.681  -17.266 0.670 20.470  0 200 SER 2 CB  1 ? 
ATOM   3337 O OG  . SER B 1 198 ? -3.740  25.278  -17.567 0.670 23.090  0 200 SER 2 OG  1 ? 
ATOM   3338 N N   . HIS B 1 199 ? -1.851  24.831  -14.402 0.670 18.420  0 201 HIS 2 N   1 ? 
ATOM   3339 C CA  . HIS B 1 199 ? -2.180  24.536  -12.993 0.670 18.840  0 201 HIS 2 CA  1 ? 
ATOM   3340 C C   . HIS B 1 199 ? -2.141  25.846  -12.197 0.670 21.100  0 201 HIS 2 C   1 ? 
ATOM   3341 O O   . HIS B 1 199 ? -1.540  26.844  -12.676 0.670 19.760  0 201 HIS 2 O   1 ? 
ATOM   3342 C CB  . HIS B 1 199 ? -1.201  23.509  -12.439 0.670 18.710  0 201 HIS 2 CB  1 ? 
ATOM   3343 C CG  . HIS B 1 199 ? 0.166   24.067  -12.247 0.670 21.820  0 201 HIS 2 CG  1 ? 
ATOM   3344 N ND1 . HIS B 1 199 ? 1.121   24.057  -13.256 0.670 24.250  0 201 HIS 2 ND1 1 ? 
ATOM   3345 C CD2 . HIS B 1 199 ? 0.740   24.656  -11.177 0.670 21.760  0 201 HIS 2 CD2 1 ? 
ATOM   3346 C CE1 . HIS B 1 199 ? 2.222   24.611  -12.808 0.670 24.000  0 201 HIS 2 CE1 1 ? 
ATOM   3347 N NE2 . HIS B 1 199 ? 2.009   25.005  -11.537 0.670 23.980  0 201 HIS 2 NE2 1 ? 
ATOM   3348 N N   . ASP B 1 200 ? -2.836  25.859  -11.067 0.670 21.430  0 202 ASP 2 N   1 ? 
ATOM   3349 C CA  . ASP B 1 200 ? -2.762  26.942  -10.062 0.670 22.490  0 202 ASP 2 CA  1 ? 
ATOM   3350 C C   . ASP B 1 200 ? -1.903  26.442  -8.895  0.670 26.340  0 202 ASP 2 C   1 ? 
ATOM   3351 O O   . ASP B 1 200 ? -1.368  25.331  -8.987  0.670 23.180  0 202 ASP 2 O   1 ? 
ATOM   3352 C CB  . ASP B 1 200 ? -4.163  27.371  -9.645  0.670 25.580  0 202 ASP 2 CB  1 ? 
ATOM   3353 C CG  . ASP B 1 200 ? -4.920  26.293  -8.918  0.670 26.020  0 202 ASP 2 CG  1 ? 
ATOM   3354 O OD1 . ASP B 1 200 ? -4.341  25.182  -8.740  0.670 22.880  0 202 ASP 2 OD1 1 ? 
ATOM   3355 O OD2 . ASP B 1 200 ? -6.069  26.573  -8.544  0.670 32.130  0 202 ASP 2 OD2 1 ? 
ATOM   3356 N N   . LYS B 1 201 ? -1.794  27.248  -7.831  0.670 26.060  0 203 LYS 2 N   1 ? 
ATOM   3357 C CA  . LYS B 1 201 ? -0.726  27.162  -6.804  0.670 29.560  0 203 LYS 2 CA  1 ? 
ATOM   3358 C C   . LYS B 1 201 ? -0.590  25.731  -6.244  0.670 28.200  0 203 LYS 2 C   1 ? 
ATOM   3359 O O   . LYS B 1 201 ? 0.549   25.198  -6.190  0.670 36.400  0 203 LYS 2 O   1 ? 
ATOM   3360 C CB  . LYS B 1 201 ? -1.022  28.223  -5.740  0.670 30.100  0 203 LYS 2 CB  1 ? 
ATOM   3361 C CG  . LYS B 1 201 ? -0.117  28.176  -4.521  0.670 36.990  0 203 LYS 2 CG  1 ? 
ATOM   3362 C CD  . LYS B 1 201 ? -0.251  29.395  -3.625  0.670 37.570  0 203 LYS 2 CD  1 ? 
ATOM   3363 C CE  . LYS B 1 201 ? 0.601   29.291  -2.379  0.670 39.590  0 203 LYS 2 CE  1 ? 
ATOM   3364 N NZ  . LYS B 1 201 ? 0.290   28.051  -1.620  0.670 41.400  0 203 LYS 2 NZ  1 ? 
ATOM   3365 N N   . ASP B 1 202 ? -1.675  25.101  -5.846  0.670 25.900  0 204 ASP 2 N   1 ? 
ATOM   3366 C CA  . ASP B 1 202 ? -1.584  23.771  -5.168  0.670 27.230  0 204 ASP 2 CA  1 ? 
ATOM   3367 C C   . ASP B 1 202 ? -2.216  22.663  -6.026  0.670 24.530  0 204 ASP 2 C   1 ? 
ATOM   3368 O O   . ASP B 1 202 ? -2.564  21.586  -5.485  0.670 24.890  0 204 ASP 2 O   1 ? 
ATOM   3369 C CB  . ASP B 1 202 ? -2.191  23.868  -3.773  0.670 29.160  0 204 ASP 2 CB  1 ? 
ATOM   3370 C CG  . ASP B 1 202 ? -1.345  24.715  -2.837  0.670 32.530  0 204 ASP 2 CG  1 ? 
ATOM   3371 O OD1 . ASP B 1 202 ? -0.091  24.508  -2.792  0.670 32.210  0 204 ASP 2 OD1 1 ? 
ATOM   3372 O OD2 . ASP B 1 202 ? -1.934  25.572  -2.182  0.670 32.620  0 204 ASP 2 OD2 1 ? 
ATOM   3373 N N   . TYR B 1 203 ? -2.307  22.879  -7.330  0.670 21.400  0 205 TYR 2 N   1 ? 
ATOM   3374 C CA  . TYR B 1 203 ? -2.945  21.941  -8.288  0.670 20.950  0 205 TYR 2 CA  1 ? 
ATOM   3375 C C   . TYR B 1 203 ? -4.404  21.698  -7.898  0.670 22.130  0 205 TYR 2 C   1 ? 
ATOM   3376 O O   . TYR B 1 203 ? -4.895  20.554  -8.065  0.670 22.500  0 205 TYR 2 O   1 ? 
ATOM   3377 C CB  . TYR B 1 203 ? -2.096  20.673  -8.424  0.670 21.960  0 205 TYR 2 CB  1 ? 
ATOM   3378 C CG  . TYR B 1 203 ? -0.764  20.869  -9.095  0.670 22.450  0 205 TYR 2 CG  1 ? 
ATOM   3379 C CD1 . TYR B 1 203 ? 0.290   21.490  -8.443  0.670 25.710  0 205 TYR 2 CD1 1 ? 
ATOM   3380 C CD2 . TYR B 1 203 ? -0.539  20.391  -10.371 0.670 23.940  0 205 TYR 2 CD2 1 ? 
ATOM   3381 C CE1 . TYR B 1 203 ? 1.513   21.678  -9.065  0.670 25.350  0 205 TYR 2 CE1 1 ? 
ATOM   3382 C CE2 . TYR B 1 203 ? 0.680   20.570  -11.003 0.670 24.540  0 205 TYR 2 CE2 1 ? 
ATOM   3383 C CZ  . TYR B 1 203 ? 1.716   21.190  -10.338 0.670 25.210  0 205 TYR 2 CZ  1 ? 
ATOM   3384 O OH  . TYR B 1 203 ? 2.910   21.347  -10.970 0.670 28.590  0 205 TYR 2 OH  1 ? 
ATOM   3385 N N   . ASN B 1 204 ? -5.095  22.734  -7.401  0.670 20.110  0 206 ASN 2 N   1 ? 
ATOM   3386 C CA  . ASN B 1 204 ? -6.566  22.675  -7.170  0.670 22.820  0 206 ASN 2 CA  1 ? 
ATOM   3387 C C   . ASN B 1 204 ? -7.317  22.739  -8.500  0.670 20.150  0 206 ASN 2 C   1 ? 
ATOM   3388 O O   . ASN B 1 204 ? -8.447  22.237  -8.534  0.670 23.200  0 206 ASN 2 O   1 ? 
ATOM   3389 C CB  . ASN B 1 204 ? -7.050  23.737  -6.183  0.670 24.120  0 206 ASN 2 CB  1 ? 
ATOM   3390 C CG  . ASN B 1 204 ? -6.595  23.392  -4.782  0.670 28.900  0 206 ASN 2 CG  1 ? 
ATOM   3391 O OD1 . ASN B 1 204 ? -6.922  22.320  -4.255  0.670 28.260  0 206 ASN 2 OD1 1 ? 
ATOM   3392 N ND2 . ASN B 1 204 ? -5.766  24.258  -4.219  0.670 30.170  0 206 ASN 2 ND2 1 ? 
ATOM   3393 N N   . LYS B 1 205 ? -6.733  23.380  -9.513  0.670 19.950  0 207 LYS 2 N   1 ? 
ATOM   3394 C CA  . LYS B 1 205 ? -7.281  23.468  -10.888 0.670 21.380  0 207 LYS 2 CA  1 ? 
ATOM   3395 C C   . LYS B 1 205 ? -6.155  23.113  -11.854 0.670 19.910  0 207 LYS 2 C   1 ? 
ATOM   3396 O O   . LYS B 1 205 ? -5.036  23.663  -11.746 0.670 20.110  0 207 LYS 2 O   1 ? 
ATOM   3397 C CB  . LYS B 1 205 ? -7.832  24.854  -11.235 0.670 26.550  0 207 LYS 2 CB  1 ? 
ATOM   3398 C CG  . LYS B 1 205 ? -9.001  25.331  -10.383 0.670 31.630  0 207 LYS 2 CG  1 ? 
ATOM   3399 C CD  . LYS B 1 205 ? -9.518  26.704  -10.781 0.670 38.650  0 207 LYS 2 CD  1 ? 
ATOM   3400 C CE  . LYS B 1 205 ? -10.747 27.111  -9.990  0.670 46.260  0 207 LYS 2 CE  1 ? 
ATOM   3401 N NZ  . LYS B 1 205 ? -11.458 28.270  -10.592 0.670 49.570  0 207 LYS 2 NZ  1 ? 
ATOM   3402 N N   . VAL B 1 206 ? -6.435  22.203  -12.760 0.670 19.110  0 208 VAL 2 N   1 ? 
ATOM   3403 C CA  . VAL B 1 206 ? -5.415  21.589  -13.645 0.670 19.220  0 208 VAL 2 CA  1 ? 
ATOM   3404 C C   . VAL B 1 206 ? -6.069  21.454  -15.022 0.670 19.990  0 208 VAL 2 C   1 ? 
ATOM   3405 O O   . VAL B 1 206 ? -7.242  21.024  -15.092 0.670 18.970  0 208 VAL 2 O   1 ? 
ATOM   3406 C CB  . VAL B 1 206 ? -4.935  20.235  -13.079 0.670 20.490  0 208 VAL 2 CB  1 ? 
ATOM   3407 C CG1 . VAL B 1 206 ? -4.031  19.501  -14.046 0.670 20.700  0 208 VAL 2 CG1 1 ? 
ATOM   3408 C CG2 . VAL B 1 206 ? -4.250  20.368  -11.712 0.670 21.520  0 208 VAL 2 CG2 1 ? 
ATOM   3409 N N   . LYS B 1 207 ? -5.303  21.734  -16.074 0.670 18.900  0 209 LYS 2 N   1 ? 
ATOM   3410 C CA  . LYS B 1 207 ? -5.679  21.413  -17.464 0.670 20.660  0 209 LYS 2 CA  1 ? 
ATOM   3411 C C   . LYS B 1 207 ? -4.766  20.276  -17.940 0.670 18.890  0 209 LYS 2 C   1 ? 
ATOM   3412 O O   . LYS B 1 207 ? -3.554  20.417  -17.833 0.670 18.820  0 209 LYS 2 O   1 ? 
ATOM   3413 C CB  . LYS B 1 207 ? -5.571  22.661  -18.344 0.670 23.410  0 209 LYS 2 CB  1 ? 
ATOM   3414 C CG  . LYS B 1 207 ? -6.215  22.526  -19.705 0.670 26.560  0 209 LYS 2 CG  1 ? 
ATOM   3415 C CD  . LYS B 1 207 ? -6.038  23.778  -20.511 0.670 31.920  0 209 LYS 2 CD  1 ? 
ATOM   3416 C CE  . LYS B 1 207 ? -6.963  23.884  -21.698 0.670 37.080  0 209 LYS 2 CE  1 ? 
ATOM   3417 N NZ  . LYS B 1 207 ? -6.638  25.112  -22.469 0.670 41.230  0 209 LYS 2 NZ  1 ? 
ATOM   3418 N N   . LEU B 1 208 ? -5.362  19.187  -18.415 0.670 17.840  0 210 LEU 2 N   1 ? 
ATOM   3419 C CA  . LEU B 1 208 ? -4.694  17.908  -18.725 0.670 18.370  0 210 LEU 2 CA  1 ? 
ATOM   3420 C C   . LEU B 1 208 ? -4.940  17.603  -20.197 0.670 17.650  0 210 LEU 2 C   1 ? 
ATOM   3421 O O   . LEU B 1 208 ? -6.024  17.892  -20.682 0.670 20.020  0 210 LEU 2 O   1 ? 
ATOM   3422 C CB  . LEU B 1 208 ? -5.279  16.841  -17.798 0.670 21.440  0 210 LEU 2 CB  1 ? 
ATOM   3423 C CG  . LEU B 1 208 ? -4.610  15.478  -17.799 0.670 24.270  0 210 LEU 2 CG  1 ? 
ATOM   3424 C CD1 . LEU B 1 208 ? -3.206  15.555  -17.228 0.670 27.470  0 210 LEU 2 CD1 1 ? 
ATOM   3425 C CD2 . LEU B 1 208 ? -5.450  14.497  -16.973 0.670 25.370  0 210 LEU 2 CD2 1 ? 
ATOM   3426 N N   . TYR B 1 209 ? -3.939  17.066  -20.870 0.670 17.280  0 211 TYR 2 N   1 ? 
ATOM   3427 C CA  . TYR B 1 209 ? -3.986  16.713  -22.295 0.670 17.820  0 211 TYR 2 CA  1 ? 
ATOM   3428 C C   . TYR B 1 209 ? -3.356  15.332  -22.463 0.670 16.560  0 211 TYR 2 C   1 ? 
ATOM   3429 O O   . TYR B 1 209 ? -2.410  14.992  -21.774 0.670 14.350  0 211 TYR 2 O   1 ? 
ATOM   3430 C CB  . TYR B 1 209 ? -3.278  17.784  -23.112 0.670 20.770  0 211 TYR 2 CB  1 ? 
ATOM   3431 C CG  . TYR B 1 209 ? -3.073  17.392  -24.540 0.670 21.760  0 211 TYR 2 CG  1 ? 
ATOM   3432 C CD1 . TYR B 1 209 ? -4.094  17.525  -25.458 0.670 26.610  0 211 TYR 2 CD1 1 ? 
ATOM   3433 C CD2 . TYR B 1 209 ? -1.869  16.871  -24.971 0.670 24.900  0 211 TYR 2 CD2 1 ? 
ATOM   3434 C CE1 . TYR B 1 209 ? -3.922  17.164  -26.781 0.670 26.620  0 211 TYR 2 CE1 1 ? 
ATOM   3435 C CE2 . TYR B 1 209 ? -1.674  16.509  -26.296 0.670 28.000  0 211 TYR 2 CE2 1 ? 
ATOM   3436 C CZ  . TYR B 1 209 ? -2.712  16.649  -27.198 0.670 29.590  0 211 TYR 2 CZ  1 ? 
ATOM   3437 O OH  . TYR B 1 209 ? -2.564  16.277  -28.505 0.670 31.870  0 211 TYR 2 OH  1 ? 
ATOM   3438 N N   . GLU B 1 210 ? -3.942  14.522  -23.320 0.670 18.390  0 212 GLU 2 N   1 ? 
ATOM   3439 C CA  . GLU B 1 210 ? -3.383  13.189  -23.616 0.670 18.820  0 212 GLU 2 CA  1 ? 
ATOM   3440 C C   . GLU B 1 210 ? -3.555  12.983  -25.111 0.670 19.140  0 212 GLU 2 C   1 ? 
ATOM   3441 O O   . GLU B 1 210 ? -4.604  13.405  -25.646 0.670 19.510  0 212 GLU 2 O   1 ? 
ATOM   3442 C CB  . GLU B 1 210 ? -4.066  12.095  -22.792 0.670 20.510  0 212 GLU 2 CB  1 ? 
ATOM   3443 C CG  . GLU B 1 210 ? -3.217  10.835  -22.663 0.670 23.950  0 212 GLU 2 CG  1 ? 
ATOM   3444 C CD  . GLU B 1 210 ? -3.774  9.515   -23.187 0.670 23.970  0 212 GLU 2 CD  1 ? 
ATOM   3445 O OE1 . GLU B 1 210 ? -4.835  9.523   -23.830 0.670 27.230  0 212 GLU 2 OE1 1 ? 
ATOM   3446 O OE2 . GLU B 1 210 ? -3.120  8.489   -22.950 0.670 22.700  0 212 GLU 2 OE2 1 ? 
ATOM   3447 N N   . HIS B 1 211 ? -2.562  12.336  -25.720 0.670 22.250  0 213 HIS 2 N   1 ? 
ATOM   3448 C CA  . HIS B 1 211 ? -2.507  11.972  -27.165 0.670 23.730  0 213 HIS 2 CA  1 ? 
ATOM   3449 C C   . HIS B 1 211 ? -2.125  10.489  -27.221 0.670 20.790  0 213 HIS 2 C   1 ? 
ATOM   3450 O O   . HIS B 1 211 ? -1.223  10.088  -26.462 0.670 19.120  0 213 HIS 2 O   1 ? 
ATOM   3451 C CB  . HIS B 1 211 ? -1.529  12.884  -27.916 0.670 25.970  0 213 HIS 2 CB  1 ? 
ATOM   3452 C CG  . HIS B 1 211 ? -1.441  12.643  -29.387 0.670 33.310  0 213 HIS 2 CG  1 ? 
ATOM   3453 N ND1 . HIS B 1 211 ? -0.342  13.046  -30.140 0.670 41.780  0 213 HIS 2 ND1 1 ? 
ATOM   3454 C CD2 . HIS B 1 211 ? -2.303  12.079  -30.264 0.670 37.970  0 213 HIS 2 CD2 1 ? 
ATOM   3455 C CE1 . HIS B 1 211 ? -0.531  12.727  -31.409 0.670 38.600  0 213 HIS 2 CE1 1 ? 
ATOM   3456 N NE2 . HIS B 1 211 ? -1.731  12.131  -31.511 0.670 36.310  0 213 HIS 2 NE2 1 ? 
ATOM   3457 N N   . ALA B 1 212 ? -2.843  9.689   -28.001 0.670 19.650  0 214 ALA 2 N   1 ? 
ATOM   3458 C CA  . ALA B 1 212 ? -2.619  8.231   -28.039 0.670 18.750  0 214 ALA 2 CA  1 ? 
ATOM   3459 C C   . ALA B 1 212 ? -2.799  7.726   -29.458 0.670 19.180  0 214 ALA 2 C   1 ? 
ATOM   3460 O O   . ALA B 1 212 ? -3.818  8.065   -30.096 0.670 20.820  0 214 ALA 2 O   1 ? 
ATOM   3461 C CB  . ALA B 1 212 ? -3.536  7.519   -27.099 0.670 19.630  0 214 ALA 2 CB  1 ? 
ATOM   3462 N N   . VAL B 1 213 ? -1.858  6.903   -29.903 0.670 19.500  0 215 VAL 2 N   1 ? 
ATOM   3463 C CA  . VAL B 1 213 ? -1.886  6.285   -31.263 0.670 19.890  0 215 VAL 2 CA  1 ? 
ATOM   3464 C C   . VAL B 1 213 ? -1.606  4.787   -31.150 0.670 18.810  0 215 VAL 2 C   1 ? 
ATOM   3465 O O   . VAL B 1 213 ? -0.531  4.415   -30.606 0.670 18.450  0 215 VAL 2 O   1 ? 
ATOM   3466 C CB  . VAL B 1 213 ? -0.881  6.958   -32.209 0.670 21.610  0 215 VAL 2 CB  1 ? 
ATOM   3467 C CG1 . VAL B 1 213 ? -1.035  6.436   -33.623 0.670 24.860  0 215 VAL 2 CG1 1 ? 
ATOM   3468 C CG2 . VAL B 1 213 ? -1.023  8.459   -32.207 0.670 23.340  0 215 VAL 2 CG2 1 ? 
ATOM   3469 N N   . ALA B 1 214 ? -2.493  3.975   -31.732 0.670 17.430  0 216 ALA 2 N   1 ? 
ATOM   3470 C CA  . ALA B 1 214 ? -2.350  2.504   -31.795 0.670 18.780  0 216 ALA 2 CA  1 ? 
ATOM   3471 C C   . ALA B 1 214 ? -1.515  2.156   -33.036 0.670 19.450  0 216 ALA 2 C   1 ? 
ATOM   3472 O O   . ALA B 1 214 ? -1.620  2.891   -34.047 0.670 17.790  0 216 ALA 2 O   1 ? 
ATOM   3473 C CB  . ALA B 1 214 ? -3.699  1.868   -31.791 0.670 19.010  0 216 ALA 2 CB  1 ? 
ATOM   3474 N N   . HIS B 1 215 ? -0.651  1.147   -32.931 0.670 21.240  0 217 HIS 2 N   1 ? 
ATOM   3475 C CA  . HIS B 1 215 ? 0.202   0.661   -34.049 0.670 22.180  0 217 HIS 2 CA  1 ? 
ATOM   3476 C C   . HIS B 1 215 ? 0.657   -0.780  -33.800 0.670 25.150  0 217 HIS 2 C   1 ? 
ATOM   3477 O O   . HIS B 1 215 ? 0.446   -1.300  -32.686 0.670 21.490  0 217 HIS 2 O   1 ? 
ATOM   3478 C CB  . HIS B 1 215 ? 1.395   1.603   -34.276 0.670 21.370  0 217 HIS 2 CB  1 ? 
ATOM   3479 C CG  . HIS B 1 215 ? 2.370   1.641   -33.150 0.670 21.840  0 217 HIS 2 CG  1 ? 
ATOM   3480 N ND1 . HIS B 1 215 ? 3.362   0.707   -33.001 0.670 22.920  0 217 HIS 2 ND1 1 ? 
ATOM   3481 C CD2 . HIS B 1 215 ? 2.450   2.446   -32.076 0.670 21.270  0 217 HIS 2 CD2 1 ? 
ATOM   3482 C CE1 . HIS B 1 215 ? 4.045   0.955   -31.905 0.670 23.730  0 217 HIS 2 CE1 1 ? 
ATOM   3483 N NE2 . HIS B 1 215 ? 3.509   2.030   -31.330 0.670 23.990  0 217 HIS 2 NE2 1 ? 
ATOM   3484 N N   . SER B 1 216 ? 1.280   -1.390  -34.817 0.670 27.730  0 218 SER 2 N   1 ? 
ATOM   3485 C CA  . SER B 1 216 ? 1.709   -2.814  -34.847 0.670 34.630  0 218 SER 2 CA  1 ? 
ATOM   3486 C C   . SER B 1 216 ? 3.228   -2.941  -34.681 0.670 37.360  0 218 SER 2 C   1 ? 
ATOM   3487 O O   . SER B 1 216 ? 3.731   -4.066  -34.802 0.670 35.350  0 218 SER 2 O   1 ? 
ATOM   3488 C CB  . SER B 1 216 ? 1.237   -3.462  -36.118 0.670 36.740  0 218 SER 2 CB  1 ? 
ATOM   3489 O OG  . SER B 1 216 ? -0.145  -3.755  -36.000 0.670 41.390  0 218 SER 2 OG  1 ? 
ATOM   3490 N N   . GLY B 1 217 ? 3.919   -1.832  -34.410 0.670 40.740  0 219 GLY 2 N   1 ? 
ATOM   3491 C CA  . GLY B 1 217 ? 5.345   -1.786  -34.030 0.670 50.320  0 219 GLY 2 CA  1 ? 
ATOM   3492 C C   . GLY B 1 217 ? 6.252   -1.442  -35.199 0.670 60.060  0 219 GLY 2 C   1 ? 
ATOM   3493 O O   . GLY B 1 217 ? 7.474   -1.592  -35.041 0.670 63.780  0 219 GLY 2 O   1 ? 
ATOM   3494 N N   . LEU B 1 218 ? 5.678   -0.994  -36.324 0.670 75.270  0 220 LEU 2 N   1 ? 
ATOM   3495 C CA  . LEU B 1 218 ? 6.392   -0.654  -37.587 0.670 85.840  0 220 LEU 2 CA  1 ? 
ATOM   3496 C C   . LEU B 1 218 ? 6.234   0.841   -37.877 0.670 99.110  0 220 LEU 2 C   1 ? 
ATOM   3497 O O   . LEU B 1 218 ? 5.402   1.520   -37.269 0.670 94.760  0 220 LEU 2 O   1 ? 
ATOM   3498 C CB  . LEU B 1 218 ? 5.823   -1.521  -38.720 0.670 86.300  0 220 LEU 2 CB  1 ? 
ATOM   3499 C CG  . LEU B 1 218 ? 6.235   -2.995  -38.693 0.670 86.740  0 220 LEU 2 CG  1 ? 
ATOM   3500 C CD1 . LEU B 1 218 ? 5.441   -3.806  -39.711 0.670 82.930  0 220 LEU 2 CD1 1 ? 
ATOM   3501 C CD2 . LEU B 1 218 ? 7.735   -3.152  -38.925 0.670 85.270  0 220 LEU 2 CD2 1 ? 
ATOM   3502 N N   . PRO B 1 219 ? 7.051   1.410   -38.799 0.670 116.030 0 221 PRO 2 N   1 ? 
ATOM   3503 C CA  . PRO B 1 219 ? 6.961   2.831   -39.146 0.670 118.600 0 221 PRO 2 CA  1 ? 
ATOM   3504 C C   . PRO B 1 219 ? 5.860   3.146   -40.177 0.670 113.850 0 221 PRO 2 C   1 ? 
ATOM   3505 O O   . PRO B 1 219 ? 5.260   4.210   -40.091 0.670 111.910 0 221 PRO 2 O   1 ? 
ATOM   3506 C CB  . PRO B 1 219 ? 8.363   3.115   -39.715 0.670 121.420 0 221 PRO 2 CB  1 ? 
ATOM   3507 C CG  . PRO B 1 219 ? 8.767   1.810   -40.378 0.670 118.960 0 221 PRO 2 CG  1 ? 
ATOM   3508 C CD  . PRO B 1 219 ? 8.123   0.720   -39.542 0.670 118.980 0 221 PRO 2 CD  1 ? 
HETATM 3509 S S   . SO4 C 2 .   ? -1.592  -3.394  -44.101 0.330 101.520 0 301 SO4 1 S   1 ? 
HETATM 3510 O O1  . SO4 C 2 .   ? -1.318  -3.592  -45.501 0.330 101.560 0 301 SO4 1 O1  1 ? 
HETATM 3511 O O2  . SO4 C 2 .   ? -3.015  -3.321  -43.893 0.330 100.890 0 301 SO4 1 O2  1 ? 
HETATM 3512 O O3  . SO4 C 2 .   ? -1.053  -4.494  -43.343 0.330 97.380  0 301 SO4 1 O3  1 ? 
HETATM 3513 O O4  . SO4 C 2 .   ? -0.982  -2.165  -43.664 0.330 101.980 0 301 SO4 1 O4  1 ? 
HETATM 3514 S S   . SO4 D 2 .   ? 3.591   -11.357 -15.492 0.330 57.550  0 302 SO4 1 S   1 ? 
HETATM 3515 O O1  . SO4 D 2 .   ? 5.011   -11.572 -15.400 0.330 55.270  0 302 SO4 1 O1  1 ? 
HETATM 3516 O O2  . SO4 D 2 .   ? 3.243   -10.144 -14.795 0.330 51.750  0 302 SO4 1 O2  1 ? 
HETATM 3517 O O3  . SO4 D 2 .   ? 3.221   -11.246 -16.884 0.330 53.820  0 302 SO4 1 O3  1 ? 
HETATM 3518 O O4  . SO4 D 2 .   ? 2.894   -12.464 -14.894 0.330 51.750  0 302 SO4 1 O4  1 ? 
HETATM 3519 S S   . SO4 E 2 .   ? -26.438 -0.798  -11.699 0.330 60.390  0 303 SO4 1 S   1 ? 
HETATM 3520 O O1  . SO4 E 2 .   ? -25.934 -2.066  -11.243 0.330 61.360  0 303 SO4 1 O1  1 ? 
HETATM 3521 O O2  . SO4 E 2 .   ? -25.669 0.263   -11.105 0.330 60.540  0 303 SO4 1 O2  1 ? 
HETATM 3522 O O3  . SO4 E 2 .   ? -26.330 -0.737  -13.137 0.330 59.780  0 303 SO4 1 O3  1 ? 
HETATM 3523 O O4  . SO4 E 2 .   ? -27.817 -0.655  -11.313 0.330 58.480  0 303 SO4 1 O4  1 ? 
HETATM 3524 S S   . SO4 F 2 .   ? -1.770  -3.098  -44.038 0.670 230.400 0 304 SO4 1 S   1 ? 
HETATM 3525 O O1  . SO4 F 2 .   ? -0.632  -3.923  -44.346 0.670 227.560 0 304 SO4 1 O1  1 ? 
HETATM 3526 O O2  . SO4 F 2 .   ? -2.320  -2.565  -45.257 0.670 230.470 0 304 SO4 1 O2  1 ? 
HETATM 3527 O O3  . SO4 F 2 .   ? -2.766  -3.888  -43.365 0.670 232.960 0 304 SO4 1 O3  1 ? 
HETATM 3528 O O4  . SO4 F 2 .   ? -1.361  -2.017  -43.182 0.670 234.400 0 304 SO4 1 O4  1 ? 
HETATM 3529 C C1  . GOL G 3 .   ? -4.922  26.781  -13.729 0.330 38.010  0 301 GOL 2 C1  1 ? 
HETATM 3530 O O1  . GOL G 3 .   ? -5.469  25.787  -14.590 0.330 40.560  0 301 GOL 2 O1  1 ? 
HETATM 3531 C C2  . GOL G 3 .   ? -5.937  27.848  -13.374 0.330 40.010  0 301 GOL 2 C2  1 ? 
HETATM 3532 O O2  . GOL G 3 .   ? -6.631  28.278  -14.545 0.330 40.250  0 301 GOL 2 O2  1 ? 
HETATM 3533 C C3  . GOL G 3 .   ? -5.310  29.051  -12.700 0.330 40.820  0 301 GOL 2 C3  1 ? 
HETATM 3534 O O3  . GOL G 3 .   ? -6.225  29.709  -11.828 0.330 40.810  0 301 GOL 2 O3  1 ? 
HETATM 3535 O O   . HOH H 4 .   ? -5.056  7.932   -13.532 0.330 36.920  0 401 HOH 1 O   1 ? 
HETATM 3536 O O   . HOH H 4 .   ? -9.149  -18.255 -19.592 0.670 47.380  0 402 HOH 1 O   1 ? 
HETATM 3537 O O   . HOH H 4 .   ? -6.090  9.743   -21.987 0.670 98.940  0 403 HOH 1 O   1 ? 
HETATM 3538 O O   . HOH H 4 .   ? -15.653 -2.629  -16.470 0.330 14.110  0 404 HOH 1 O   1 ? 
HETATM 3539 O O   . HOH H 4 .   ? -20.849 -9.723  -27.378 0.330 20.660  0 405 HOH 1 O   1 ? 
HETATM 3540 O O   . HOH H 4 .   ? 1.354   -11.215 -18.522 0.670 35.610  0 406 HOH 1 O   1 ? 
HETATM 3541 O O   . HOH H 4 .   ? -2.548  -1.972  -37.705 0.330 37.690  0 407 HOH 1 O   1 ? 
HETATM 3542 O O   . HOH H 4 .   ? -8.536  25.604  -19.523 0.670 41.070  0 408 HOH 1 O   1 ? 
HETATM 3543 O O   . HOH H 4 .   ? 1.663   0.431   2.253   0.330 15.870  0 409 HOH 1 O   1 ? 
HETATM 3544 O O   . HOH H 4 .   ? -13.837 -3.746  -33.456 0.330 36.950  0 410 HOH 1 O   1 ? 
HETATM 3545 O O   . HOH H 4 .   ? -14.783 2.064   -4.322  0.670 31.570  0 411 HOH 1 O   1 ? 
HETATM 3546 O O   . HOH H 4 .   ? 3.973   19.489  -21.358 0.330 32.000  0 412 HOH 1 O   1 ? 
HETATM 3547 O O   . HOH H 4 .   ? -23.431 8.545   -33.374 0.670 61.280  0 413 HOH 1 O   1 ? 
HETATM 3548 O O   . HOH H 4 .   ? 20.079  15.712  -10.886 0.330 51.960  0 414 HOH 1 O   1 ? 
HETATM 3549 O O   . HOH H 4 .   ? -11.539 14.810  -36.148 0.330 29.740  0 415 HOH 1 O   1 ? 
HETATM 3550 O O   . HOH H 4 .   ? 2.811   9.045   -20.741 0.330 24.730  0 416 HOH 1 O   1 ? 
HETATM 3551 O O   . HOH H 4 .   ? 3.199   20.179  -12.672 0.330 25.620  0 417 HOH 1 O   1 ? 
HETATM 3552 O O   . HOH H 4 .   ? 5.035   2.744   -35.455 0.330 36.280  0 418 HOH 1 O   1 ? 
HETATM 3553 O O   . HOH H 4 .   ? -19.278 12.343  -4.646  0.670 43.490  0 419 HOH 1 O   1 ? 
HETATM 3554 O O   . HOH H 4 .   ? 15.353  16.415  -13.036 0.670 29.280  0 420 HOH 1 O   1 ? 
HETATM 3555 O O   . HOH H 4 .   ? -13.649 23.621  -6.266  0.330 22.110  0 421 HOH 1 O   1 ? 
HETATM 3556 O O   . HOH H 4 .   ? -4.749  26.967  -5.719  0.670 43.390  0 422 HOH 1 O   1 ? 
HETATM 3557 O O   . HOH H 4 .   ? -13.847 5.775   -2.678  0.330 39.320  0 423 HOH 1 O   1 ? 
HETATM 3558 O O   . HOH H 4 .   ? -1.464  -10.178 -14.015 0.330 37.710  0 424 HOH 1 O   1 ? 
HETATM 3559 O O   . HOH H 4 .   ? -15.740 25.522  -7.613  0.330 23.380  0 425 HOH 1 O   1 ? 
HETATM 3560 O O   . HOH H 4 .   ? -16.741 19.898  -21.410 0.330 23.030  0 426 HOH 1 O   1 ? 
HETATM 3561 O O   . HOH H 4 .   ? -21.249 -3.384  -26.948 0.330 44.480  0 427 HOH 1 O   1 ? 
HETATM 3562 O O   . HOH H 4 .   ? 1.374   -1.232  2.225   0.670 78.620  0 428 HOH 1 O   1 ? 
HETATM 3563 O O   . HOH H 4 .   ? -13.610 -2.858  -34.523 0.670 73.800  0 429 HOH 1 O   1 ? 
HETATM 3564 O O   . HOH H 4 .   ? -1.799  7.711   -13.100 0.330 34.420  0 430 HOH 1 O   1 ? 
HETATM 3565 O O   . HOH H 4 .   ? -8.735  8.828   5.676   0.330 40.210  0 431 HOH 1 O   1 ? 
HETATM 3566 O O   . HOH H 4 .   ? -5.191  20.649  -4.486  0.330 30.690  0 432 HOH 1 O   1 ? 
HETATM 3567 O O   . HOH H 4 .   ? -8.260  24.315  -16.003 0.670 34.720  0 433 HOH 1 O   1 ? 
HETATM 3568 O O   . HOH H 4 .   ? -6.262  7.345   -24.754 0.670 21.100  0 434 HOH 1 O   1 ? 
HETATM 3569 O O   . HOH H 4 .   ? 14.005  6.880   -8.011  0.330 16.330  0 435 HOH 1 O   1 ? 
HETATM 3570 O O   . HOH H 4 .   ? 5.535   6.526   -25.971 0.330 28.180  0 436 HOH 1 O   1 ? 
HETATM 3571 O O   . HOH H 4 .   ? -23.747 4.017   -22.075 0.670 32.400  0 437 HOH 1 O   1 ? 
HETATM 3572 O O   . HOH H 4 .   ? 5.299   15.595  -22.446 0.670 56.170  0 438 HOH 1 O   1 ? 
HETATM 3573 O O   . HOH H 4 .   ? 1.920   -5.706  -33.478 0.330 16.670  0 439 HOH 1 O   1 ? 
HETATM 3574 O O   . HOH H 4 .   ? 3.779   7.275   -19.698 0.670 26.530  0 440 HOH 1 O   1 ? 
HETATM 3575 O O   . HOH H 4 .   ? -12.706 12.620  -33.606 0.330 17.960  0 441 HOH 1 O   1 ? 
HETATM 3576 O O   . HOH H 4 .   ? 18.171  9.953   -13.937 0.670 130.060 0 442 HOH 1 O   1 ? 
HETATM 3577 O O   . HOH H 4 .   ? 2.422   25.898  -7.990  0.670 27.270  0 443 HOH 1 O   1 ? 
HETATM 3578 O O   . HOH H 4 .   ? -15.196 -8.634  -24.377 0.330 36.510  0 444 HOH 1 O   1 ? 
HETATM 3579 O O   . HOH H 4 .   ? 15.226  7.509   -17.462 0.330 34.630  0 445 HOH 1 O   1 ? 
HETATM 3580 O O   . HOH H 4 .   ? -19.286 2.611   -31.689 0.670 41.570  0 446 HOH 1 O   1 ? 
HETATM 3581 O O   . HOH H 4 .   ? 3.871   -7.284  -20.644 0.670 38.630  0 447 HOH 1 O   1 ? 
HETATM 3582 O O   . HOH H 4 .   ? -6.680  -11.880 -17.391 0.670 36.060  0 448 HOH 1 O   1 ? 
HETATM 3583 O O   . HOH H 4 .   ? -7.280  8.213   -22.031 0.330 15.350  0 449 HOH 1 O   1 ? 
HETATM 3584 O O   . HOH H 4 .   ? -6.794  -11.540 -29.034 0.330 35.190  0 450 HOH 1 O   1 ? 
HETATM 3585 O O   . HOH H 4 .   ? -20.839 -2.935  -27.596 0.670 30.490  0 451 HOH 1 O   1 ? 
HETATM 3586 O O   . HOH H 4 .   ? 6.839   1.732   0.845   0.670 36.120  0 452 HOH 1 O   1 ? 
HETATM 3587 O O   . HOH H 4 .   ? -17.183 -3.897  -17.940 0.670 39.320  0 453 HOH 1 O   1 ? 
HETATM 3588 O O   . HOH H 4 .   ? -1.226  19.976  -3.652  0.670 26.460  0 454 HOH 1 O   1 ? 
HETATM 3589 O O   . HOH H 4 .   ? -8.237  23.702  2.042   0.330 23.400  0 455 HOH 1 O   1 ? 
HETATM 3590 O O   . HOH H 4 .   ? 1.292   -2.823  -11.798 0.670 26.240  0 456 HOH 1 O   1 ? 
HETATM 3591 O O   . HOH H 4 .   ? 4.177   7.589   -18.382 0.330 25.510  0 457 HOH 1 O   1 ? 
HETATM 3592 O O   . HOH H 4 .   ? -1.016  -1.180  -37.927 0.670 43.650  0 458 HOH 1 O   1 ? 
HETATM 3593 O O   . HOH H 4 .   ? -8.432  -2.463  -29.468 0.670 17.360  0 459 HOH 1 O   1 ? 
HETATM 3594 O O   . HOH H 4 .   ? 5.796   -0.333  -21.797 0.330 26.350  0 460 HOH 1 O   1 ? 
HETATM 3595 O O   . HOH H 4 .   ? -29.328 5.789   -19.907 0.330 36.990  0 461 HOH 1 O   1 ? 
HETATM 3596 O O   . HOH H 4 .   ? 2.796   -2.140  -37.154 0.330 17.090  0 462 HOH 1 O   1 ? 
HETATM 3597 O O   . HOH H 4 .   ? -11.191 -2.077  -39.367 0.670 38.350  0 463 HOH 1 O   1 ? 
HETATM 3598 O O   . HOH H 4 .   ? 4.160   6.964   4.628   0.330 27.720  0 464 HOH 1 O   1 ? 
HETATM 3599 O O   . HOH H 4 .   ? -15.253 -8.560  -24.833 0.670 25.490  0 465 HOH 1 O   1 ? 
HETATM 3600 O O   . HOH H 4 .   ? 2.614   16.199  1.975   0.670 27.180  0 466 HOH 1 O   1 ? 
HETATM 3601 O O   . HOH H 4 .   ? -0.586  9.930   5.255   0.670 38.730  0 467 HOH 1 O   1 ? 
HETATM 3602 O O   . HOH H 4 .   ? -4.799  26.993  -19.166 0.330 18.160  0 468 HOH 1 O   1 ? 
HETATM 3603 O O   . HOH H 4 .   ? -20.141 -2.781  -24.449 0.670 26.840  0 469 HOH 1 O   1 ? 
HETATM 3604 O O   . HOH H 4 .   ? -8.299  24.079  -15.545 0.330 49.200  0 470 HOH 1 O   1 ? 
HETATM 3605 O O   . HOH H 4 .   ? -16.581 -6.436  -32.205 0.330 49.440  0 471 HOH 1 O   1 ? 
HETATM 3606 O O   . HOH H 4 .   ? 4.373   13.120  -21.348 0.330 29.490  0 472 HOH 1 O   1 ? 
HETATM 3607 O O   . HOH H 4 .   ? -23.520 9.877   -29.594 0.330 27.680  0 473 HOH 1 O   1 ? 
HETATM 3608 O O   . HOH H 4 .   ? -7.087  -11.711 -29.701 0.670 40.590  0 474 HOH 1 O   1 ? 
HETATM 3609 O O   . HOH H 4 .   ? -17.734 18.403  -2.538  0.330 32.710  0 475 HOH 1 O   1 ? 
HETATM 3610 O O   . HOH H 4 .   ? -6.978  7.501   -22.296 0.670 17.760  0 476 HOH 1 O   1 ? 
HETATM 3611 O O   . HOH H 4 .   ? -16.109 6.747   -3.099  0.670 52.240  0 477 HOH 1 O   1 ? 
HETATM 3612 O O   . HOH H 4 .   ? -9.242  9.274   5.862   0.670 43.280  0 478 HOH 1 O   1 ? 
HETATM 3613 O O   . HOH H 4 .   ? -17.721 -3.701  -17.819 0.330 32.560  0 479 HOH 1 O   1 ? 
HETATM 3614 O O   . HOH H 4 .   ? -9.224  7.385   -36.595 0.670 28.060  0 480 HOH 1 O   1 ? 
HETATM 3615 O O   . HOH H 4 .   ? -5.745  -16.025 -22.715 0.330 18.450  0 481 HOH 1 O   1 ? 
HETATM 3616 O O   . HOH H 4 .   ? -10.346 3.801   -29.457 0.670 19.390  0 482 HOH 1 O   1 ? 
HETATM 3617 O O   . HOH H 4 .   ? 7.603   18.869  -7.890  0.330 40.040  0 483 HOH 1 O   1 ? 
HETATM 3618 O O   . HOH H 4 .   ? 6.737   14.861  -22.133 0.330 34.150  0 484 HOH 1 O   1 ? 
HETATM 3619 O O   . HOH H 4 .   ? 4.779   14.153  -20.382 0.670 26.480  0 485 HOH 1 O   1 ? 
HETATM 3620 O O   . HOH H 4 .   ? -20.125 -2.852  -24.454 0.330 30.480  0 486 HOH 1 O   1 ? 
HETATM 3621 O O   . HOH H 4 .   ? 6.545   3.282   -22.063 0.330 16.020  0 487 HOH 1 O   1 ? 
HETATM 3622 O O   . HOH H 4 .   ? 7.182   7.848   -3.400  0.670 20.490  0 488 HOH 1 O   1 ? 
HETATM 3623 O O   . HOH H 4 .   ? 5.009   16.733  -7.674  0.330 29.810  0 489 HOH 1 O   1 ? 
HETATM 3624 O O   . HOH H 4 .   ? -11.652 -7.993  -22.203 0.670 18.840  0 490 HOH 1 O   1 ? 
HETATM 3625 O O   . HOH H 4 .   ? -10.304 3.786   -29.448 0.330 23.200  0 491 HOH 1 O   1 ? 
HETATM 3626 O O   . HOH H 4 .   ? 0.882   14.086  -15.173 0.670 21.770  0 492 HOH 1 O   1 ? 
HETATM 3627 O O   . HOH H 4 .   ? -18.294 18.722  -2.087  0.670 45.840  0 493 HOH 1 O   1 ? 
HETATM 3628 O O   . HOH H 4 .   ? -0.520  21.684  -0.368  0.330 35.800  0 494 HOH 1 O   1 ? 
HETATM 3629 O O   . HOH H 4 .   ? -3.002  11.624  -34.002 0.330 22.450  0 495 HOH 1 O   1 ? 
HETATM 3630 O O   . HOH H 4 .   ? -3.099  -15.560 -23.416 0.670 31.850  0 496 HOH 1 O   1 ? 
HETATM 3631 O O   . HOH H 4 .   ? -28.861 5.566   -18.765 0.670 31.390  0 497 HOH 1 O   1 ? 
HETATM 3632 O O   . HOH H 4 .   ? -4.835  20.333  -4.465  0.670 23.960  0 498 HOH 1 O   1 ? 
HETATM 3633 O O   . HOH H 4 .   ? 3.059   -0.092  -37.132 0.670 37.860  0 499 HOH 1 O   1 ? 
HETATM 3634 O O   . HOH H 4 .   ? -24.388 1.025   -19.895 0.670 34.710  0 500 HOH 1 O   1 ? 
HETATM 3635 O O   . HOH H 4 .   ? 7.186   7.955   -3.372  0.330 25.840  0 501 HOH 1 O   1 ? 
HETATM 3636 O O   . HOH H 4 .   ? -4.955  -9.994  -17.282 0.670 37.180  0 502 HOH 1 O   1 ? 
HETATM 3637 O O   . HOH H 4 .   ? -11.667 -8.081  -22.199 0.330 19.350  0 503 HOH 1 O   1 ? 
HETATM 3638 O O   . HOH H 4 .   ? 3.656   8.773   -27.231 0.330 31.650  0 504 HOH 1 O   1 ? 
HETATM 3639 O O   . HOH H 4 .   ? 1.989   22.839  -5.370  0.670 47.960  0 505 HOH 1 O   1 ? 
HETATM 3640 O O   . HOH H 4 .   ? 11.514  12.926  -1.665  0.670 20.280  0 506 HOH 1 O   1 ? 
HETATM 3641 O O   . HOH H 4 .   ? 3.635   20.652  -19.444 0.670 24.940  0 507 HOH 1 O   1 ? 
HETATM 3642 O O   . HOH H 4 .   ? -21.526 17.377  -21.704 0.670 35.350  0 508 HOH 1 O   1 ? 
HETATM 3643 O O   . HOH H 4 .   ? -1.736  -9.529  -12.981 0.670 52.700  0 509 HOH 1 O   1 ? 
HETATM 3644 O O   . HOH H 4 .   ? 17.371  9.708   -14.412 0.330 11.760  0 510 HOH 1 O   1 ? 
HETATM 3645 O O   . HOH H 4 .   ? -22.482 10.643  -29.718 0.670 47.210  0 511 HOH 1 O   1 ? 
HETATM 3646 O O   . HOH H 4 .   ? -8.540  -2.342  -28.959 0.330 24.350  0 512 HOH 1 O   1 ? 
HETATM 3647 O O   . HOH H 4 .   ? 11.293  6.887   -1.936  0.670 28.690  0 513 HOH 1 O   1 ? 
HETATM 3648 O O   . HOH H 4 .   ? -20.195 6.069   -15.784 0.670 22.870  0 514 HOH 1 O   1 ? 
HETATM 3649 O O   . HOH H 4 .   ? 4.058   18.054  -11.302 0.670 32.860  0 515 HOH 1 O   1 ? 
HETATM 3650 O O   . HOH H 4 .   ? 5.598   18.024  -21.467 0.330 27.300  0 516 HOH 1 O   1 ? 
HETATM 3651 O O   . HOH H 4 .   ? 6.236   0.294   -21.650 0.670 26.820  0 517 HOH 1 O   1 ? 
HETATM 3652 O O   . HOH H 4 .   ? 2.634   -4.498  -15.823 0.670 39.420  0 518 HOH 1 O   1 ? 
HETATM 3653 O O   . HOH H 4 .   ? -13.213 -10.287 -21.456 0.670 37.690  0 519 HOH 1 O   1 ? 
HETATM 3654 O O   . HOH H 4 .   ? -9.667  21.572  -21.739 0.330 18.270  0 520 HOH 1 O   1 ? 
HETATM 3655 O O   . HOH H 4 .   ? -26.011 13.842  -22.416 0.670 32.140  0 521 HOH 1 O   1 ? 
HETATM 3656 O O   . HOH H 4 .   ? -13.623 6.582   -2.467  0.670 33.250  0 522 HOH 1 O   1 ? 
HETATM 3657 O O   . HOH H 4 .   ? -23.709 4.150   -21.430 0.330 38.740  0 523 HOH 1 O   1 ? 
HETATM 3658 O O   . HOH H 4 .   ? -9.771  0.212   -36.371 0.670 36.650  0 524 HOH 1 O   1 ? 
HETATM 3659 O O   . HOH H 4 .   ? -25.198 13.891  -21.930 0.330 26.980  0 525 HOH 1 O   1 ? 
HETATM 3660 O O   . HOH H 4 .   ? -20.190 5.877   -15.632 0.330 25.150  0 526 HOH 1 O   1 ? 
HETATM 3661 O O   . HOH H 4 .   ? -3.475  -6.491  -33.891 0.670 36.050  0 527 HOH 1 O   1 ? 
HETATM 3662 O O   . HOH H 4 .   ? 2.344   14.979  2.725   0.330 28.670  0 528 HOH 1 O   1 ? 
HETATM 3663 O O   . HOH H 4 .   ? -25.031 -1.339  -20.125 0.330 47.710  0 529 HOH 1 O   1 ? 
HETATM 3664 O O   . HOH H 4 .   ? 0.669   3.811   3.745   0.330 9.000   0 530 HOH 1 O   1 ? 
HETATM 3665 O O   . HOH H 4 .   ? 7.798   -0.894  -9.961  0.670 39.120  0 531 HOH 1 O   1 ? 
HETATM 3666 O O   . HOH H 4 .   ? 3.873   20.811  -17.366 0.330 21.230  0 532 HOH 1 O   1 ? 
HETATM 3667 O O   . HOH H 4 .   ? -11.803 13.494  -36.354 0.670 28.480  0 533 HOH 1 O   1 ? 
HETATM 3668 O O   . HOH H 4 .   ? -5.820  3.829   0.337   0.330 20.530  0 534 HOH 1 O   1 ? 
HETATM 3669 O O   . HOH H 4 .   ? -17.777 19.260  -21.679 0.670 38.720  0 535 HOH 1 O   1 ? 
HETATM 3670 O O   . HOH H 4 .   ? -4.375  5.243   -13.167 0.670 59.110  0 536 HOH 1 O   1 ? 
HETATM 3671 O O   . HOH H 4 .   ? -2.841  -11.529 -30.807 0.330 22.510  0 537 HOH 1 O   1 ? 
HETATM 3672 O O   . HOH H 4 .   ? 3.054   17.096  -17.307 0.670 17.350  0 538 HOH 1 O   1 ? 
HETATM 3673 O O   . HOH H 4 .   ? 3.085   17.241  -17.173 0.330 14.620  0 539 HOH 1 O   1 ? 
HETATM 3674 O O   . HOH H 4 .   ? 3.563   10.506  -20.842 0.670 20.490  0 540 HOH 1 O   1 ? 
HETATM 3675 O O   . HOH H 4 .   ? -8.465  3.484   -20.431 0.670 27.050  0 541 HOH 1 O   1 ? 
HETATM 3676 O O   . HOH H 4 .   ? 2.779   20.125  -13.810 0.670 25.690  0 542 HOH 1 O   1 ? 
HETATM 3677 O O   . HOH H 4 .   ? 4.927   16.883  -7.359  0.670 22.060  0 543 HOH 1 O   1 ? 
HETATM 3678 O O   . HOH H 4 .   ? -13.048 -12.484 -28.924 0.670 28.260  0 544 HOH 1 O   1 ? 
HETATM 3679 O O   . HOH H 4 .   ? -6.675  -6.604  -34.076 0.670 24.720  0 545 HOH 1 O   1 ? 
HETATM 3680 O O   . HOH H 4 .   ? -9.033  12.344  4.821   0.670 34.920  0 546 HOH 1 O   1 ? 
HETATM 3681 O O   . HOH H 4 .   ? -16.785 -6.943  -32.371 0.670 39.900  0 547 HOH 1 O   1 ? 
HETATM 3682 O O   . HOH H 4 .   ? 16.367  16.564  -15.986 0.670 29.690  0 548 HOH 1 O   1 ? 
HETATM 3683 O O   . HOH H 4 .   ? 4.954   7.386   -26.773 0.670 26.650  0 549 HOH 1 O   1 ? 
HETATM 3684 O O   . HOH H 4 .   ? 3.969   18.252  -11.193 0.330 28.520  0 550 HOH 1 O   1 ? 
HETATM 3685 O O   . HOH H 4 .   ? -0.849  19.872  0.842   0.670 44.540  0 551 HOH 1 O   1 ? 
HETATM 3686 O O   . HOH H 4 .   ? -5.708  -5.032  -13.546 0.670 37.170  0 552 HOH 1 O   1 ? 
HETATM 3687 O O   . HOH H 4 .   ? -3.990  0.613   -2.656  0.670 32.000  0 553 HOH 1 O   1 ? 
HETATM 3688 O O   . HOH H 4 .   ? 3.901   -8.582  -21.109 0.330 37.010  0 554 HOH 1 O   1 ? 
HETATM 3689 O O   . HOH H 4 .   ? -18.986 18.043  -28.459 0.330 25.660  0 555 HOH 1 O   1 ? 
HETATM 3690 O O   . HOH H 4 .   ? 15.113  19.153  -12.688 0.330 22.020  0 556 HOH 1 O   1 ? 
HETATM 3691 O O   . HOH H 4 .   ? -12.779 0.081   -41.697 0.330 23.820  0 557 HOH 1 O   1 ? 
HETATM 3692 O O   . HOH H 4 .   ? 2.900   -5.841  -14.384 0.330 44.790  0 558 HOH 1 O   1 ? 
HETATM 3693 O O   . HOH H 4 .   ? 5.055   17.556  -20.197 0.330 33.340  0 559 HOH 1 O   1 ? 
HETATM 3694 O O   . HOH H 4 .   ? -18.226 9.241   -29.015 0.670 78.080  0 560 HOH 1 O   1 ? 
HETATM 3695 O O   . HOH H 4 .   ? 13.108  7.695   -5.804  0.330 29.810  0 561 HOH 1 O   1 ? 
HETATM 3696 O O   . HOH H 4 .   ? -9.723  -18.555 -22.012 0.330 20.190  0 562 HOH 1 O   1 ? 
HETATM 3697 O O   . HOH H 4 .   ? -7.292  18.098  -27.388 0.330 25.540  0 563 HOH 1 O   1 ? 
HETATM 3698 O O   . HOH H 4 .   ? -5.899  14.457  0.923   0.670 44.150  0 564 HOH 1 O   1 ? 
HETATM 3699 O O   . HOH H 4 .   ? -14.456 -12.129 -27.617 0.330 26.950  0 565 HOH 1 O   1 ? 
HETATM 3700 O O   . HOH H 4 .   ? 2.080   9.912   -28.384 0.670 35.150  0 566 HOH 1 O   1 ? 
HETATM 3701 O O   . HOH H 4 .   ? -5.629  30.262  -7.500  0.670 42.840  0 567 HOH 1 O   1 ? 
HETATM 3702 O O   . HOH H 4 .   ? -14.939 -7.743  -20.035 0.330 40.710  0 568 HOH 1 O   1 ? 
HETATM 3703 O O   . HOH H 4 .   ? 11.258  4.134   -17.384 0.330 15.800  0 569 HOH 1 O   1 ? 
HETATM 3704 O O   . HOH H 4 .   ? -16.323 -5.350  -16.064 0.670 42.970  0 570 HOH 1 O   1 ? 
HETATM 3705 O O   . HOH H 4 .   ? 12.459  6.826   -3.407  0.330 20.790  0 571 HOH 1 O   1 ? 
HETATM 3706 O O   . HOH H 4 .   ? 2.576   22.116  -5.056  0.330 26.700  0 572 HOH 1 O   1 ? 
HETATM 3707 O O   . HOH H 4 .   ? -5.495  1.233   -1.335  0.330 28.100  0 573 HOH 1 O   1 ? 
HETATM 3708 O O   . HOH H 4 .   ? 12.515  12.659  -4.186  0.330 34.390  0 574 HOH 1 O   1 ? 
HETATM 3709 O O   . HOH H 4 .   ? -5.048  -18.912 -20.867 0.670 34.760  0 575 HOH 1 O   1 ? 
HETATM 3710 O O   . HOH H 4 .   ? 6.574   21.429  -12.182 0.670 39.270  0 576 HOH 1 O   1 ? 
HETATM 3711 O O   . HOH H 4 .   ? -21.081 4.285   -14.313 0.670 52.590  0 577 HOH 1 O   1 ? 
HETATM 3712 O O   . HOH H 4 .   ? -14.192 0.368   -34.969 0.670 44.280  0 578 HOH 1 O   1 ? 
HETATM 3713 O O   . HOH H 4 .   ? -5.083  -18.746 -21.137 0.330 26.990  0 579 HOH 1 O   1 ? 
HETATM 3714 O O   . HOH H 4 .   ? 2.421   9.068   -30.792 0.330 27.210  0 580 HOH 1 O   1 ? 
HETATM 3715 O O   . HOH H 4 .   ? -5.553  19.419  -28.917 0.670 46.740  0 581 HOH 1 O   1 ? 
HETATM 3716 O O   . HOH H 4 .   ? -14.433 -9.797  -19.951 0.330 53.280  0 582 HOH 1 O   1 ? 
HETATM 3717 O O   . HOH H 4 .   ? -16.736 25.058  -4.985  0.670 40.920  0 583 HOH 1 O   1 ? 
HETATM 3718 O O   . HOH H 4 .   ? -1.916  20.298  -26.412 0.670 43.390  0 584 HOH 1 O   1 ? 
HETATM 3719 O O   . HOH H 4 .   ? 14.067  4.980   -15.713 0.670 37.680  0 585 HOH 1 O   1 ? 
HETATM 3720 O O   . HOH H 4 .   ? 2.534   -5.137  -13.237 0.670 35.840  0 586 HOH 1 O   1 ? 
HETATM 3721 O O   . HOH H 4 .   ? 13.288  12.443  -4.177  0.670 39.990  0 587 HOH 1 O   1 ? 
HETATM 3722 O O   . HOH H 4 .   ? -8.019  -10.469 -15.428 0.670 33.060  0 588 HOH 1 O   1 ? 
HETATM 3723 O O   . HOH I 4 .   ? -5.499  25.359  -15.301 0.670 41.540  0 401 HOH 2 O   1 ? 
HETATM 3724 O O   . HOH I 4 .   ? -2.473  -14.346 -15.794 0.330 39.520  0 402 HOH 2 O   1 ? 
HETATM 3725 O O   . HOH I 4 .   ? -3.459  26.233  -2.562  0.330 21.480  0 403 HOH 2 O   1 ? 
HETATM 3726 O O   . HOH I 4 .   ? -6.847  0.073   -42.421 0.330 23.370  0 404 HOH 2 O   1 ? 
HETATM 3727 O O   . HOH I 4 .   ? -5.539  6.534   -24.499 0.330 19.620  0 405 HOH 2 O   1 ? 
HETATM 3728 O O   . HOH I 4 .   ? 17.241  16.050  -15.008 0.330 20.230  0 406 HOH 2 O   1 ? 
HETATM 3729 O O   . HOH I 4 .   ? -3.447  26.014  -5.659  0.330 29.610  0 407 HOH 2 O   1 ? 
HETATM 3730 O O   . HOH I 4 .   ? -13.097 27.943  -11.756 0.330 25.840  0 408 HOH 2 O   1 ? 
HETATM 3731 O O   . HOH I 4 .   ? -1.313  -5.797  -33.599 0.330 81.500  0 409 HOH 2 O   1 ? 
HETATM 3732 O O   . HOH I 4 .   ? 9.775   7.773   4.734   0.330 13.590  0 410 HOH 2 O   1 ? 
HETATM 3733 O O   . HOH I 4 .   ? 3.019   20.816  -22.001 0.670 51.260  0 411 HOH 2 O   1 ? 
HETATM 3734 O O   . HOH I 4 .   ? -5.177  14.337  2.970   0.330 25.540  0 412 HOH 2 O   1 ? 
HETATM 3735 O O   . HOH I 4 .   ? -12.296 -4.909  -36.445 0.330 27.840  0 413 HOH 2 O   1 ? 
HETATM 3736 O O   . HOH I 4 .   ? -0.647  4.088   -35.638 0.330 37.800  0 414 HOH 2 O   1 ? 
HETATM 3737 O O   . HOH I 4 .   ? 8.256   5.628   -20.131 0.330 15.710  0 415 HOH 2 O   1 ? 
HETATM 3738 O O   . HOH I 4 .   ? 15.151  18.119  -2.689  0.670 28.610  0 416 HOH 2 O   1 ? 
HETATM 3739 O O   . HOH I 4 .   ? -16.523 -3.944  -36.340 0.670 40.470  0 417 HOH 2 O   1 ? 
HETATM 3740 O O   . HOH I 4 .   ? -2.059  -0.292  -18.219 0.330 20.080  0 418 HOH 2 O   1 ? 
HETATM 3741 O O   . HOH I 4 .   ? 1.165   -2.827  -10.888 0.330 22.540  0 419 HOH 2 O   1 ? 
HETATM 3742 O O   . HOH I 4 .   ? -5.908  10.403  -25.649 0.330 18.200  0 420 HOH 2 O   1 ? 
HETATM 3743 O O   . HOH I 4 .   ? -6.632  15.787  1.357   0.670 29.540  0 421 HOH 2 O   1 ? 
HETATM 3744 O O   . HOH I 4 .   ? 6.679   1.252   -0.171  0.330 31.800  0 422 HOH 2 O   1 ? 
HETATM 3745 O O   . HOH I 4 .   ? -1.703  -14.903 -14.918 0.670 51.280  0 423 HOH 2 O   1 ? 
HETATM 3746 O O   . HOH I 4 .   ? -15.165 22.449  -3.144  0.330 27.420  0 424 HOH 2 O   1 ? 
HETATM 3747 O O   . HOH I 4 .   ? -6.996  -7.087  -33.601 0.330 37.610  0 425 HOH 2 O   1 ? 
HETATM 3748 O O   . HOH I 4 .   ? -18.451 12.422  -6.365  0.330 23.120  0 426 HOH 2 O   1 ? 
HETATM 3749 O O   . HOH I 4 .   ? 2.739   14.104  -17.655 0.330 22.330  0 427 HOH 2 O   1 ? 
HETATM 3750 O O   . HOH I 4 .   ? 14.667  4.439   -10.836 0.670 44.530  0 428 HOH 2 O   1 ? 
HETATM 3751 O O   . HOH I 4 .   ? -1.957  -0.249  -18.919 0.670 24.160  0 429 HOH 2 O   1 ? 
HETATM 3752 O O   . HOH I 4 .   ? 10.988  13.375  -22.112 0.670 37.690  0 430 HOH 2 O   1 ? 
HETATM 3753 O O   . HOH I 4 .   ? -9.236  -4.334  -38.172 0.670 36.020  0 431 HOH 2 O   1 ? 
HETATM 3754 O O   . HOH I 4 .   ? -15.561 2.859   -11.084 0.670 29.770  0 432 HOH 2 O   1 ? 
HETATM 3755 O O   . HOH I 4 .   ? -10.746 10.368  -20.424 0.330 21.470  0 433 HOH 2 O   1 ? 
HETATM 3756 O O   . HOH I 4 .   ? 0.259   14.215  -15.222 0.330 20.210  0 434 HOH 2 O   1 ? 
HETATM 3757 O O   . HOH I 4 .   ? 3.912   7.321   -31.668 0.330 36.270  0 435 HOH 2 O   1 ? 
HETATM 3758 O O   . HOH I 4 .   ? -5.291  4.848   1.344   0.670 30.800  0 436 HOH 2 O   1 ? 
HETATM 3759 O O   . HOH I 4 .   ? -10.892 10.619  -20.283 0.670 18.790  0 437 HOH 2 O   1 ? 
HETATM 3760 O O   . HOH I 4 .   ? -0.687  3.544   -36.305 0.670 33.910  0 438 HOH 2 O   1 ? 
HETATM 3761 O O   . HOH I 4 .   ? -0.830  -5.567  -34.372 0.330 22.590  0 439 HOH 2 O   1 ? 
HETATM 3762 O O   . HOH I 4 .   ? -10.034 -0.433  -36.334 0.330 24.260  0 440 HOH 2 O   1 ? 
HETATM 3763 O O   . HOH I 4 .   ? -4.369  26.205  -2.505  0.670 43.070  0 441 HOH 2 O   1 ? 
HETATM 3764 O O   . HOH I 4 .   ? -4.153  0.146   -41.050 0.330 33.050  0 442 HOH 2 O   1 ? 
HETATM 3765 O O   . HOH I 4 .   ? 3.252   17.232  -14.494 0.330 20.020  0 443 HOH 2 O   1 ? 
HETATM 3766 O O   . HOH I 4 .   ? -1.285  8.167   -13.162 0.670 20.910  0 444 HOH 2 O   1 ? 
HETATM 3767 O O   . HOH I 4 .   ? -13.758 27.439  -8.468  0.670 53.990  0 445 HOH 2 O   1 ? 
HETATM 3768 O O   . HOH I 4 .   ? -17.777 -4.640  -35.666 0.330 36.560  0 446 HOH 2 O   1 ? 
HETATM 3769 O O   . HOH I 4 .   ? -6.679  29.180  -9.368  0.670 41.760  0 447 HOH 2 O   1 ? 
HETATM 3770 O O   . HOH I 4 .   ? -11.876 18.731  -28.292 0.330 17.010  0 448 HOH 2 O   1 ? 
HETATM 3771 O O   . HOH I 4 .   ? -11.225 -5.866  -14.721 0.330 27.430  0 449 HOH 2 O   1 ? 
HETATM 3772 O O   . HOH I 4 .   ? 2.020   18.169  -3.432  0.330 28.240  0 450 HOH 2 O   1 ? 
HETATM 3773 O O   . HOH I 4 .   ? -11.265 -5.120  -16.115 0.670 37.540  0 451 HOH 2 O   1 ? 
HETATM 3774 O O   . HOH I 4 .   ? 13.004  13.704  -19.984 0.670 24.220  0 452 HOH 2 O   1 ? 
HETATM 3775 O O   . HOH I 4 .   ? -11.062 2.904   -34.854 0.670 25.810  0 453 HOH 2 O   1 ? 
HETATM 3776 O O   . HOH I 4 .   ? 3.198   17.351  -14.468 0.670 18.280  0 454 HOH 2 O   1 ? 
HETATM 3777 O O   . HOH I 4 .   ? 1.823   -0.601  -37.244 0.330 15.010  0 455 HOH 2 O   1 ? 
HETATM 3778 O O   . HOH I 4 .   ? 12.775  14.140  -19.342 0.330 22.900  0 456 HOH 2 O   1 ? 
HETATM 3779 O O   . HOH I 4 .   ? 0.570   8.980   -28.955 0.330 30.280  0 457 HOH 2 O   1 ? 
HETATM 3780 O O   . HOH I 4 .   ? -13.292 18.359  -29.479 0.670 26.000  0 458 HOH 2 O   1 ? 
HETATM 3781 O O   . HOH I 4 .   ? 5.534   -1.241  -5.336  0.670 36.780  0 459 HOH 2 O   1 ? 
HETATM 3782 O O   . HOH I 4 .   ? -0.830  19.881  -4.421  0.330 20.900  0 460 HOH 2 O   1 ? 
HETATM 3783 O O   . HOH I 4 .   ? -15.679 2.987   -10.684 0.330 38.950  0 461 HOH 2 O   1 ? 
HETATM 3784 O O   . HOH I 4 .   ? -24.553 7.144   -17.505 0.670 30.700  0 462 HOH 2 O   1 ? 
HETATM 3785 O O   . HOH I 4 .   ? -11.965 3.037   -34.711 0.330 34.180  0 463 HOH 2 O   1 ? 
HETATM 3786 O O   . HOH I 4 .   ? -7.232  5.958   -37.962 0.670 47.590  0 464 HOH 2 O   1 ? 
HETATM 3787 O O   . HOH I 4 .   ? -19.653 0.234   -15.269 0.670 72.100  0 465 HOH 2 O   1 ? 
HETATM 3788 O O   . HOH I 4 .   ? 3.481   5.018   4.256   0.670 32.190  0 466 HOH 2 O   1 ? 
HETATM 3789 O O   . HOH I 4 .   ? -22.251 -8.080  -28.668 0.670 49.950  0 467 HOH 2 O   1 ? 
HETATM 3790 O O   . HOH I 4 .   ? -6.237  10.745  -25.864 0.670 32.810  0 468 HOH 2 O   1 ? 
HETATM 3791 O O   . HOH I 4 .   ? 15.419  5.485   -10.983 0.330 26.980  0 469 HOH 2 O   1 ? 
HETATM 3792 O O   . HOH I 4 .   ? 2.997   14.242  -17.451 0.670 17.710  0 470 HOH 2 O   1 ? 
HETATM 3793 O O   . HOH I 4 .   ? -13.226 -13.539 -23.405 0.670 40.940  0 471 HOH 2 O   1 ? 
HETATM 3794 O O   . HOH I 4 .   ? -13.680 9.690   -20.692 0.670 16.870  0 472 HOH 2 O   1 ? 
HETATM 3795 O O   . HOH I 4 .   ? -15.045 7.622   -2.042  0.330 40.540  0 473 HOH 2 O   1 ? 
HETATM 3796 O O   . HOH I 4 .   ? 2.245   16.652  -9.240  0.670 23.490  0 474 HOH 2 O   1 ? 
HETATM 3797 O O   . HOH I 4 .   ? -9.217  23.454  -13.883 0.330 32.830  0 475 HOH 2 O   1 ? 
HETATM 3798 O O   . HOH I 4 .   ? -25.848 4.554   -20.524 0.670 35.460  0 476 HOH 2 O   1 ? 
HETATM 3799 O O   . HOH I 4 .   ? 6.112   9.318   -1.253  0.330 23.390  0 477 HOH 2 O   1 ? 
HETATM 3800 O O   . HOH I 4 .   ? 3.242   -3.980  -16.130 0.330 26.660  0 478 HOH 2 O   1 ? 
HETATM 3801 O O   . HOH I 4 .   ? -2.568  29.358  -12.976 0.670 41.180  0 479 HOH 2 O   1 ? 
HETATM 3802 O O   . HOH I 4 .   ? -22.889 -1.953  -26.112 0.330 34.860  0 480 HOH 2 O   1 ? 
HETATM 3803 O O   . HOH I 4 .   ? 6.112   9.280   -1.267  0.670 19.820  0 481 HOH 2 O   1 ? 
HETATM 3804 O O   . HOH I 4 .   ? 7.184   2.596   -22.774 0.670 49.660  0 482 HOH 2 O   1 ? 
HETATM 3805 O O   . HOH I 4 .   ? -16.204 -8.118  -21.475 0.670 47.350  0 483 HOH 2 O   1 ? 
HETATM 3806 O O   . HOH I 4 .   ? 0.400   18.043  -5.852  0.330 20.640  0 484 HOH 2 O   1 ? 
HETATM 3807 O O   . HOH I 4 .   ? -0.796  18.060  -5.645  0.670 28.300  0 485 HOH 2 O   1 ? 
HETATM 3808 O O   . HOH I 4 .   ? -23.133 16.839  -21.301 0.330 22.280  0 486 HOH 2 O   1 ? 
HETATM 3809 O O   . HOH I 4 .   ? -6.407  15.304  1.308   0.330 27.400  0 487 HOH 2 O   1 ? 
HETATM 3810 O O   . HOH I 4 .   ? -18.219 9.326   -8.723  0.330 18.960  0 488 HOH 2 O   1 ? 
HETATM 3811 O O   . HOH I 4 .   ? -12.071 12.882  -33.794 0.670 25.150  0 489 HOH 2 O   1 ? 
HETATM 3812 O O   . HOH I 4 .   ? -17.391 13.191  0.075   0.670 32.450  0 490 HOH 2 O   1 ? 
HETATM 3813 O O   . HOH I 4 .   ? -13.291 9.849   -20.542 0.330 22.620  0 491 HOH 2 O   1 ? 
HETATM 3814 O O   . HOH I 4 .   ? -4.400  8.275   -37.914 0.330 30.640  0 492 HOH 2 O   1 ? 
HETATM 3815 O O   . HOH I 4 .   ? 12.274  16.344  -19.837 0.330 22.770  0 493 HOH 2 O   1 ? 
HETATM 3816 O O   . HOH I 4 .   ? 6.532   2.495   -29.928 0.330 25.500  0 494 HOH 2 O   1 ? 
HETATM 3817 O O   . HOH I 4 .   ? -8.841  6.246   -36.383 0.330 39.050  0 495 HOH 2 O   1 ? 
HETATM 3818 O O   . HOH I 4 .   ? 19.993  9.727   -12.126 0.670 27.100  0 496 HOH 2 O   1 ? 
HETATM 3819 O O   . HOH I 4 .   ? 7.925   20.181  -3.380  0.330 28.020  0 497 HOH 2 O   1 ? 
HETATM 3820 O O   . HOH I 4 .   ? -10.084 23.632  -13.739 0.670 26.150  0 498 HOH 2 O   1 ? 
HETATM 3821 O O   . HOH I 4 .   ? 5.846   -2.089  -24.679 0.330 30.010  0 499 HOH 2 O   1 ? 
HETATM 3822 O O   . HOH I 4 .   ? -2.418  30.037  -8.189  0.670 39.510  0 500 HOH 2 O   1 ? 
HETATM 3823 O O   . HOH I 4 .   ? 2.838   9.255   4.358   0.330 32.500  0 501 HOH 2 O   1 ? 
HETATM 3824 O O   . HOH I 4 .   ? 7.426   6.393   5.496   0.670 29.770  0 502 HOH 2 O   1 ? 
HETATM 3825 O O   . HOH I 4 .   ? 7.873   19.081  -8.160  0.670 36.650  0 503 HOH 2 O   1 ? 
HETATM 3826 O O   . HOH I 4 .   ? -19.647 22.119  -7.423  0.330 22.380  0 504 HOH 2 O   1 ? 
HETATM 3827 O O   . HOH I 4 .   ? -22.881 -1.006  -26.949 0.670 36.110  0 505 HOH 2 O   1 ? 
HETATM 3828 O O   . HOH I 4 .   ? -10.240 5.131   -34.334 0.330 24.840  0 506 HOH 2 O   1 ? 
HETATM 3829 O O   . HOH I 4 .   ? 4.022   11.636  -21.582 0.330 15.400  0 507 HOH 2 O   1 ? 
HETATM 3830 O O   . HOH I 4 .   ? 5.078   13.663  3.635   0.670 19.220  0 508 HOH 2 O   1 ? 
HETATM 3831 O O   . HOH I 4 .   ? -5.692  2.815   -41.351 0.670 42.430  0 509 HOH 2 O   1 ? 
HETATM 3832 O O   . HOH I 4 .   ? 5.427   19.699  -10.233 0.670 34.050  0 510 HOH 2 O   1 ? 
HETATM 3833 O O   . HOH I 4 .   ? -9.471  5.622   -34.688 0.670 21.520  0 511 HOH 2 O   1 ? 
HETATM 3834 O O   . HOH I 4 .   ? -5.281  0.415   -42.153 0.670 44.700  0 512 HOH 2 O   1 ? 
HETATM 3835 O O   . HOH I 4 .   ? -11.888 -1.479  -35.464 0.670 28.350  0 513 HOH 2 O   1 ? 
HETATM 3836 O O   . HOH I 4 .   ? -3.919  29.189  -15.316 0.670 78.290  0 514 HOH 2 O   1 ? 
HETATM 3837 O O   . HOH I 4 .   ? 1.614   13.940  -28.098 0.670 72.680  0 515 HOH 2 O   1 ? 
HETATM 3838 O O   . HOH I 4 .   ? -10.811 -3.574  -37.893 0.330 43.680  0 516 HOH 2 O   1 ? 
HETATM 3839 O O   . HOH I 4 .   ? 1.872   -6.181  -28.619 0.670 42.030  0 517 HOH 2 O   1 ? 
HETATM 3840 O O   . HOH I 4 .   ? -2.745  30.046  -8.165  0.330 26.910  0 518 HOH 2 O   1 ? 
HETATM 3841 O O   . HOH I 4 .   ? -19.503 1.982   -14.881 0.330 23.110  0 519 HOH 2 O   1 ? 
HETATM 3842 O O   . HOH I 4 .   ? 7.665   20.411  -2.723  0.670 39.660  0 520 HOH 2 O   1 ? 
HETATM 3843 O O   . HOH I 4 .   ? 17.122  7.884   -11.553 0.670 38.330  0 521 HOH 2 O   1 ? 
HETATM 3844 O O   . HOH I 4 .   ? -3.126  28.877  -14.256 0.330 31.220  0 522 HOH 2 O   1 ? 
HETATM 3845 O O   . HOH I 4 .   ? -5.670  15.460  3.182   0.670 25.700  0 523 HOH 2 O   1 ? 
HETATM 3846 O O   . HOH I 4 .   ? -12.484 -1.591  -35.202 0.330 32.020  0 524 HOH 2 O   1 ? 
HETATM 3847 O O   . HOH I 4 .   ? -11.216 -12.493 -34.362 0.330 46.410  0 525 HOH 2 O   1 ? 
HETATM 3848 O O   . HOH I 4 .   ? -5.408  5.547   -37.796 0.330 43.970  0 526 HOH 2 O   1 ? 
HETATM 3849 O O   . HOH I 4 .   ? 1.490   10.065  4.220   0.670 34.080  0 527 HOH 2 O   1 ? 
HETATM 3850 O O   . HOH I 4 .   ? 6.195   6.453   5.826   0.330 21.110  0 528 HOH 2 O   1 ? 
HETATM 3851 O O   . HOH I 4 .   ? 1.639   -6.460  -27.661 0.330 32.390  0 529 HOH 2 O   1 ? 
HETATM 3852 O O   . HOH I 4 .   ? 4.887   -3.645  -16.802 0.670 41.170  0 530 HOH 2 O   1 ? 
HETATM 3853 O O   . HOH I 4 .   ? -4.114  -5.124  -12.275 0.330 33.010  0 531 HOH 2 O   1 ? 
HETATM 3854 O O   . HOH I 4 .   ? 1.742   18.240  -7.220  0.670 36.090  0 532 HOH 2 O   1 ? 
HETATM 3855 O O   . HOH I 4 .   ? 2.070   17.191  -10.041 0.330 19.070  0 533 HOH 2 O   1 ? 
HETATM 3856 O O   . HOH I 4 .   ? 1.209   13.466  4.595   0.330 33.070  0 534 HOH 2 O   1 ? 
HETATM 3857 O O   . HOH I 4 .   ? 14.598  17.429  -13.770 0.330 20.340  0 535 HOH 2 O   1 ? 
HETATM 3858 O O   . HOH I 4 .   ? 7.046   19.194  -16.862 0.670 36.480  0 536 HOH 2 O   1 ? 
HETATM 3859 O O   . HOH I 4 .   ? 7.218   5.789   -26.527 0.330 21.270  0 537 HOH 2 O   1 ? 
HETATM 3860 O O   . HOH I 4 .   ? 2.113   18.241  -7.458  0.330 27.800  0 538 HOH 2 O   1 ? 
HETATM 3861 O O   . HOH I 4 .   ? 17.236  7.299   -11.999 0.330 46.820  0 539 HOH 2 O   1 ? 
HETATM 3862 O O   . HOH I 4 .   ? -0.040  19.414  -26.325 0.330 30.640  0 540 HOH 2 O   1 ? 
HETATM 3863 O O   . HOH I 4 .   ? 0.563   0.765   -37.567 0.670 41.290  0 541 HOH 2 O   1 ? 
HETATM 3864 O O   . HOH I 4 .   ? -11.530 8.553   4.545   0.670 56.080  0 542 HOH 2 O   1 ? 
HETATM 3865 O O   . HOH I 4 .   ? 4.680   3.410   4.439   0.330 20.770  0 543 HOH 2 O   1 ? 
HETATM 3866 O O   . HOH I 4 .   ? 6.793   -2.826  -5.108  0.330 43.330  0 544 HOH 2 O   1 ? 
HETATM 3867 O O   . HOH I 4 .   ? 1.227   14.311  4.595   0.670 36.000  0 545 HOH 2 O   1 ? 
HETATM 3868 O O   . HOH I 4 .   ? -11.480 8.892   4.594   0.330 29.060  0 546 HOH 2 O   1 ? 
HETATM 3869 O O   . HOH I 4 .   ? 2.262   14.474  -27.948 0.330 32.040  0 547 HOH 2 O   1 ? 
HETATM 3870 O O   . HOH I 4 .   ? -4.713  3.212   -41.491 0.330 34.140  0 548 HOH 2 O   1 ? 
HETATM 3871 O O   . HOH I 4 .   ? 3.887   11.714  4.610   0.330 69.300  0 549 HOH 2 O   1 ? 
HETATM 3872 O O   . HOH I 4 .   ? -3.639  -6.816  -12.417 0.330 19.510  0 550 HOH 2 O   1 ? 
HETATM 3873 O O   . HOH I 4 .   ? -22.004 3.167   -14.862 0.330 22.760  0 551 HOH 2 O   1 ? 
HETATM 3874 O O   . HOH I 4 .   ? -20.989 8.220   -13.933 0.330 22.650  0 552 HOH 2 O   1 ? 
HETATM 3875 O O   . HOH I 4 .   ? -3.749  5.619   -38.528 0.330 32.120  0 553 HOH 2 O   1 ? 
HETATM 3876 O O   . HOH I 4 .   ? -13.536 3.225   -35.520 0.330 26.560  0 554 HOH 2 O   1 ? 
HETATM 3877 O O   . HOH I 4 .   ? -12.217 13.842  -17.161 0.670 83.210  0 555 HOH 2 O   1 ? 
HETATM 3878 O O   . HOH I 4 .   ? -3.963  4.052   -40.585 0.330 48.190  0 556 HOH 2 O   1 ? 
HETATM 3879 O O   . HOH I 4 .   ? 8.807   23.137  -11.468 0.670 45.490  0 557 HOH 2 O   1 ? 
HETATM 3880 O O   . HOH I 4 .   ? 7.512   22.521  -11.403 0.330 31.170  0 558 HOH 2 O   1 ? 
# 
