data_8UJI
# 
_entry.id   8UJI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UJI         pdb_00008uji 10.2210/pdb8uji/pdb 
WWPDB D_1000277248 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UJI 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              hunter@salk.edu 
_pdbx_contact_author.name_first         Tony 
_pdbx_contact_author.name_last          Hunter 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7691-6993 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kalagiri, R.'    1 0000-0002-4817-3563 
'Stanfield, R.L.' 2 0000-0001-9521-9184 
'Hunter, T.'      3 0000-0002-7691-6993 
'Wilson, I.A.'    4 0000-0002-6469-2419 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.11.04.621849 
_citation.pdbx_database_id_PubMed   39574610 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Martyn, G.D.'     1  ?                   
primary 'Kalagiri, R.'     2  ?                   
primary 'Veggiani, G.'     3  ?                   
primary 'Stanfield, R.L.'  4  ?                   
primary 'Choudhuri, I.'    5  ?                   
primary 'Sala, M.'         6  ?                   
primary 'Meisenhelder, J.' 7  ?                   
primary 'Chen, C.'         8  ?                   
primary 'Biswas, A.'       9  ?                   
primary 'Levy, R.M.'       10 ?                   
primary 'Lyumkis, D.'      11 ?                   
primary 'Wilson, I.A.'     12 ?                   
primary 'Hunter, T.'       13 0000-0002-7691-6993 
primary 'Sidhu, S.S.'      14 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'hSC44.CK Fab heavy chain' 23502.344 2   ? ? ? ? 
2 polymer     man 'hSC44.CK Fab light chain' 23879.383 2   ? ? ? ? 
3 polymer     syn '3-pTza peptide'           748.641   2   ? ? ? ? 
4 non-polymer syn 1,2-ETHANEDIOL             62.068    1   ? ? ? ? 
5 water       nat water                      18.015    219 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGSGNPVAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGSGNPVAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
H,A ? 
2 'polypeptide(L)' no no  
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
L,B ? 
3 'polypeptide(L)' no yes 'AGAG(UKD)AGAG' AGAGXAGAG C,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 1,2-ETHANEDIOL EDO 
5 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  THR n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  SER n 
1 29  ILE n 
1 30  ASP n 
1 31  SER n 
1 32  TYR n 
1 33  GLY n 
1 34  PHE n 
1 35  SER n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  HIS n 
1 48  ILE n 
1 49  GLY n 
1 50  TYR n 
1 51  LEU n 
1 52  THR n 
1 53  ALA n 
1 54  GLY n 
1 55  GLY n 
1 56  ARG n 
1 57  ALA n 
1 58  PHE n 
1 59  TYR n 
1 60  ALA n 
1 61  SER n 
1 62  TRP n 
1 63  ALA n 
1 64  LYS n 
1 65  SER n 
1 66  ARG n 
1 67  SER n 
1 68  THR n 
1 69  ILE n 
1 70  THR n 
1 71  ARG n 
1 72  ASN n 
1 73  THR n 
1 74  ASN n 
1 75  GLU n 
1 76  ASN n 
1 77  THR n 
1 78  VAL n 
1 79  THR n 
1 80  LEU n 
1 81  LYS n 
1 82  MET n 
1 83  ASN n 
1 84  SER n 
1 85  LEU n 
1 86  ARG n 
1 87  ALA n 
1 88  GLU n 
1 89  ASP n 
1 90  THR n 
1 91  ALA n 
1 92  VAL n 
1 93  TYR n 
1 94  TYR n 
1 95  CYS n 
1 96  ALA n 
1 97  LYS n 
1 98  LEU n 
1 99  GLY n 
1 100 SER n 
1 101 GLY n 
1 102 ASN n 
1 103 PRO n 
1 104 VAL n 
1 105 ALA n 
1 106 ILE n 
1 107 TRP n 
1 108 GLY n 
1 109 GLN n 
1 110 GLY n 
1 111 THR n 
1 112 LEU n 
1 113 VAL n 
1 114 THR n 
1 115 VAL n 
1 116 SER n 
1 117 SER n 
1 118 ALA n 
1 119 SER n 
1 120 THR n 
1 121 LYS n 
1 122 GLY n 
1 123 PRO n 
1 124 SER n 
1 125 VAL n 
1 126 PHE n 
1 127 PRO n 
1 128 LEU n 
1 129 ALA n 
1 130 PRO n 
1 131 SER n 
1 132 SER n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 SER n 
1 137 GLY n 
1 138 GLY n 
1 139 THR n 
1 140 ALA n 
1 141 ALA n 
1 142 LEU n 
1 143 GLY n 
1 144 CYS n 
1 145 LEU n 
1 146 VAL n 
1 147 LYS n 
1 148 ASP n 
1 149 TYR n 
1 150 PHE n 
1 151 PRO n 
1 152 GLU n 
1 153 PRO n 
1 154 VAL n 
1 155 THR n 
1 156 VAL n 
1 157 SER n 
1 158 TRP n 
1 159 ASN n 
1 160 SER n 
1 161 GLY n 
1 162 ALA n 
1 163 LEU n 
1 164 THR n 
1 165 SER n 
1 166 GLY n 
1 167 VAL n 
1 168 HIS n 
1 169 THR n 
1 170 PHE n 
1 171 PRO n 
1 172 ALA n 
1 173 VAL n 
1 174 LEU n 
1 175 GLN n 
1 176 SER n 
1 177 SER n 
1 178 GLY n 
1 179 LEU n 
1 180 TYR n 
1 181 SER n 
1 182 LEU n 
1 183 SER n 
1 184 SER n 
1 185 VAL n 
1 186 VAL n 
1 187 THR n 
1 188 VAL n 
1 189 PRO n 
1 190 SER n 
1 191 SER n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 THR n 
1 196 GLN n 
1 197 THR n 
1 198 TYR n 
1 199 ILE n 
1 200 CYS n 
1 201 ASN n 
1 202 VAL n 
1 203 ASN n 
1 204 HIS n 
1 205 LYS n 
1 206 PRO n 
1 207 SER n 
1 208 ASN n 
1 209 THR n 
1 210 LYS n 
1 211 VAL n 
1 212 ASP n 
1 213 LYS n 
1 214 LYS n 
1 215 VAL n 
1 216 GLU n 
1 217 PRO n 
1 218 LYS n 
1 219 SER n 
1 220 CYS n 
1 221 ASP n 
1 222 LYS n 
1 223 THR n 
1 224 HIS n 
1 225 THR n 
2 1   ASP n 
2 2   ILE n 
2 3   GLN n 
2 4   MET n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   SER n 
2 10  SER n 
2 11  LEU n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  VAL n 
2 16  GLY n 
2 17  ASP n 
2 18  ARG n 
2 19  VAL n 
2 20  THR n 
2 21  ILE n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  VAL n 
2 30  TRP n 
2 31  ARG n 
2 32  ASN n 
2 33  LYS n 
2 34  ASN n 
2 35  VAL n 
2 36  ALA n 
2 37  TRP n 
2 38  TYR n 
2 39  GLN n 
2 40  GLN n 
2 41  LYS n 
2 42  PRO n 
2 43  GLY n 
2 44  LYS n 
2 45  ALA n 
2 46  PRO n 
2 47  LYS n 
2 48  ARG n 
2 49  LEU n 
2 50  ILE n 
2 51  TYR n 
2 52  ALA n 
2 53  ILE n 
2 54  ALA n 
2 55  SER n 
2 56  LEU n 
2 57  TYR n 
2 58  SER n 
2 59  GLY n 
2 60  VAL n 
2 61  PRO n 
2 62  SER n 
2 63  ARG n 
2 64  PHE n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  SER n 
2 70  GLY n 
2 71  THR n 
2 72  ASP n 
2 73  PHE n 
2 74  THR n 
2 75  LEU n 
2 76  THR n 
2 77  ILE n 
2 78  SER n 
2 79  SER n 
2 80  LEU n 
2 81  GLN n 
2 82  PRO n 
2 83  GLU n 
2 84  ASP n 
2 85  PHE n 
2 86  ALA n 
2 87  THR n 
2 88  TYR n 
2 89  TYR n 
2 90  CYS n 
2 91  VAL n 
2 92  GLY n 
2 93  HIS n 
2 94  TYR n 
2 95  GLY n 
2 96  SER n 
2 97  GLU n 
2 98  ASN n 
2 99  ASP n 
2 100 ALA n 
2 101 TYR n 
2 102 TYR n 
2 103 ALA n 
2 104 PHE n 
2 105 GLY n 
2 106 GLN n 
2 107 GLY n 
2 108 THR n 
2 109 LYS n 
2 110 VAL n 
2 111 GLU n 
2 112 ILE n 
2 113 LYS n 
2 114 ARG n 
2 115 THR n 
2 116 VAL n 
2 117 ALA n 
2 118 ALA n 
2 119 PRO n 
2 120 SER n 
2 121 VAL n 
2 122 PHE n 
2 123 ILE n 
2 124 PHE n 
2 125 PRO n 
2 126 PRO n 
2 127 SER n 
2 128 ASP n 
2 129 GLU n 
2 130 GLN n 
2 131 LEU n 
2 132 LYS n 
2 133 SER n 
2 134 GLY n 
2 135 THR n 
2 136 ALA n 
2 137 SER n 
2 138 VAL n 
2 139 VAL n 
2 140 CYS n 
2 141 LEU n 
2 142 LEU n 
2 143 ASN n 
2 144 ASN n 
2 145 PHE n 
2 146 TYR n 
2 147 PRO n 
2 148 ARG n 
2 149 GLU n 
2 150 ALA n 
2 151 LYS n 
2 152 VAL n 
2 153 SER n 
2 154 TRP n 
2 155 TYR n 
2 156 VAL n 
2 157 ASP n 
2 158 ASN n 
2 159 ALA n 
2 160 LEU n 
2 161 GLN n 
2 162 SER n 
2 163 GLY n 
2 164 ASN n 
2 165 SER n 
2 166 GLN n 
2 167 GLU n 
2 168 SER n 
2 169 VAL n 
2 170 THR n 
2 171 GLU n 
2 172 GLN n 
2 173 ASP n 
2 174 SER n 
2 175 LYS n 
2 176 ASP n 
2 177 SER n 
2 178 THR n 
2 179 TYR n 
2 180 SER n 
2 181 LEU n 
2 182 SER n 
2 183 SER n 
2 184 THR n 
2 185 LEU n 
2 186 THR n 
2 187 LEU n 
2 188 SER n 
2 189 LYS n 
2 190 ALA n 
2 191 ASP n 
2 192 TYR n 
2 193 GLU n 
2 194 LYS n 
2 195 HIS n 
2 196 LYS n 
2 197 VAL n 
2 198 TYR n 
2 199 ALA n 
2 200 CYS n 
2 201 GLU n 
2 202 VAL n 
2 203 THR n 
2 204 GLN n 
2 205 GLY n 
2 206 THR n 
2 207 THR n 
2 208 SER n 
2 209 VAL n 
2 210 THR n 
2 211 LYS n 
2 212 SER n 
2 213 PHE n 
2 214 ASN n 
2 215 ARG n 
2 216 GLY n 
2 217 GLU n 
2 218 CYS n 
3 1   ALA n 
3 2   GLY n 
3 3   ALA n 
3 4   GLY n 
3 5   UKD n 
3 6   ALA n 
3 7   GLY n 
3 8   ALA n 
3 9   GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 225 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? expi293F ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 218 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? expi293F ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              3 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       9 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                           ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                          ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                        ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                   ?                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                          ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL                                    'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE                                         ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                   ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                           ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                         ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                             ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                        ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                           ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                            ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                        ?                 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                     ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                           ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                            ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                         ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                        ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                          ?                 'C9 H11 N O3'    181.189 
UKD 'L-peptide linking' . '3-(4-phosphono-1H-1,2,3-triazol-1-yl)-L-alanine' pHis              'C5 H9 N4 O5 P'  236.123 
VAL 'L-peptide linking' y VALINE                                            ?                 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   ?   ?   ?   H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  ARG 19  19  19  ARG ARG H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  THR 23  23  23  THR THR H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  ILE 29  29  29  ILE ILE H . n 
A 1 30  ASP 30  30  30  ASP ASP H . n 
A 1 31  SER 31  31  31  SER SER H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  GLY 33  33  33  GLY GLY H . n 
A 1 34  PHE 34  34  34  PHE PHE H . n 
A 1 35  SER 35  35  35  SER SER H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  ALA 40  40  40  ALA ALA H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  HIS 47  47  47  HIS HIS H . n 
A 1 48  ILE 48  48  48  ILE ILE H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  TYR 50  50  50  TYR TYR H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  THR 52  52  52  THR THR H . n 
A 1 53  ALA 53  53  53  ALA ALA H . n 
A 1 54  GLY 54  54  54  GLY GLY H . n 
A 1 55  GLY 55  55  55  GLY GLY H . n 
A 1 56  ARG 56  56  56  ARG ARG H . n 
A 1 57  ALA 57  57  57  ALA ALA H . n 
A 1 58  PHE 58  58  58  PHE PHE H . n 
A 1 59  TYR 59  59  59  TYR TYR H . n 
A 1 60  ALA 60  60  60  ALA ALA H . n 
A 1 61  SER 61  61  61  SER SER H . n 
A 1 62  TRP 62  62  62  TRP TRP H . n 
A 1 63  ALA 63  63  63  ALA ALA H . n 
A 1 64  LYS 64  64  64  LYS LYS H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  ARG 66  66  66  ARG ARG H . n 
A 1 67  SER 67  67  67  SER SER H . n 
A 1 68  THR 68  68  68  THR THR H . n 
A 1 69  ILE 69  69  69  ILE ILE H . n 
A 1 70  THR 70  70  70  THR THR H . n 
A 1 71  ARG 71  71  71  ARG ARG H . n 
A 1 72  ASN 72  72  72  ASN ASN H . n 
A 1 73  THR 73  73  73  THR THR H . n 
A 1 74  ASN 74  74  74  ASN ASN H . n 
A 1 75  GLU 75  75  75  GLU GLU H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  THR 77  77  77  THR THR H . n 
A 1 78  VAL 78  78  78  VAL VAL H . n 
A 1 79  THR 79  79  79  THR THR H . n 
A 1 80  LEU 80  80  80  LEU LEU H . n 
A 1 81  LYS 81  81  81  LYS LYS H . n 
A 1 82  MET 82  82  82  MET MET H . n 
A 1 83  ASN 83  82  82  ASN ASN H A n 
A 1 84  SER 84  82  82  SER SER H B n 
A 1 85  LEU 85  82  82  LEU LEU H C n 
A 1 86  ARG 86  83  83  ARG ARG H . n 
A 1 87  ALA 87  84  84  ALA ALA H . n 
A 1 88  GLU 88  85  85  GLU GLU H . n 
A 1 89  ASP 89  86  86  ASP ASP H . n 
A 1 90  THR 90  87  87  THR THR H . n 
A 1 91  ALA 91  88  88  ALA ALA H . n 
A 1 92  VAL 92  89  89  VAL VAL H . n 
A 1 93  TYR 93  90  90  TYR TYR H . n 
A 1 94  TYR 94  91  91  TYR TYR H . n 
A 1 95  CYS 95  92  92  CYS CYS H . n 
A 1 96  ALA 96  93  93  ALA ALA H . n 
A 1 97  LYS 97  94  94  LYS LYS H . n 
A 1 98  LEU 98  95  95  LEU LEU H . n 
A 1 99  GLY 99  96  96  GLY GLY H . n 
A 1 100 SER 100 97  97  SER SER H . n 
A 1 101 GLY 101 98  98  GLY GLY H . n 
A 1 102 ASN 102 99  99  ASN ASN H . n 
A 1 103 PRO 103 100 100 PRO PRO H . n 
A 1 104 VAL 104 100 100 VAL VAL H A n 
A 1 105 ALA 105 101 101 ALA ALA H . n 
A 1 106 ILE 106 102 102 ILE ILE H . n 
A 1 107 TRP 107 103 103 TRP TRP H . n 
A 1 108 GLY 108 104 104 GLY GLY H . n 
A 1 109 GLN 109 105 105 GLN GLN H . n 
A 1 110 GLY 110 106 106 GLY GLY H . n 
A 1 111 THR 111 107 107 THR THR H . n 
A 1 112 LEU 112 108 108 LEU LEU H . n 
A 1 113 VAL 113 109 109 VAL VAL H . n 
A 1 114 THR 114 110 110 THR THR H . n 
A 1 115 VAL 115 111 111 VAL VAL H . n 
A 1 116 SER 116 112 112 SER SER H . n 
A 1 117 SER 117 113 113 SER SER H . n 
A 1 118 ALA 118 114 114 ALA ALA H . n 
A 1 119 SER 119 115 115 SER SER H . n 
A 1 120 THR 120 116 116 THR THR H . n 
A 1 121 LYS 121 117 117 LYS LYS H . n 
A 1 122 GLY 122 118 118 GLY GLY H . n 
A 1 123 PRO 123 119 119 PRO PRO H . n 
A 1 124 SER 124 120 120 SER SER H . n 
A 1 125 VAL 125 121 121 VAL VAL H . n 
A 1 126 PHE 126 122 122 PHE PHE H . n 
A 1 127 PRO 127 123 123 PRO PRO H . n 
A 1 128 LEU 128 124 124 LEU LEU H . n 
A 1 129 ALA 129 125 125 ALA ALA H . n 
A 1 130 PRO 130 126 126 PRO PRO H . n 
A 1 131 SER 131 127 127 SER SER H . n 
A 1 132 SER 132 128 128 SER SER H . n 
A 1 133 LYS 133 129 129 LYS LYS H . n 
A 1 134 SER 134 130 130 SER SER H . n 
A 1 135 THR 135 131 131 THR THR H . n 
A 1 136 SER 136 132 132 SER SER H . n 
A 1 137 GLY 137 133 133 GLY GLY H . n 
A 1 138 GLY 138 134 134 GLY GLY H . n 
A 1 139 THR 139 135 135 THR THR H . n 
A 1 140 ALA 140 136 136 ALA ALA H . n 
A 1 141 ALA 141 137 137 ALA ALA H . n 
A 1 142 LEU 142 138 138 LEU LEU H . n 
A 1 143 GLY 143 139 139 GLY GLY H . n 
A 1 144 CYS 144 140 140 CYS CYS H . n 
A 1 145 LEU 145 141 141 LEU LEU H . n 
A 1 146 VAL 146 142 142 VAL VAL H . n 
A 1 147 LYS 147 143 143 LYS LYS H . n 
A 1 148 ASP 148 144 144 ASP ASP H . n 
A 1 149 TYR 149 145 145 TYR TYR H . n 
A 1 150 PHE 150 146 146 PHE PHE H . n 
A 1 151 PRO 151 147 147 PRO PRO H . n 
A 1 152 GLU 152 148 148 GLU GLU H . n 
A 1 153 PRO 153 149 149 PRO PRO H . n 
A 1 154 VAL 154 150 150 VAL VAL H . n 
A 1 155 THR 155 151 151 THR THR H . n 
A 1 156 VAL 156 152 152 VAL VAL H . n 
A 1 157 SER 157 153 153 SER SER H . n 
A 1 158 TRP 158 154 154 TRP TRP H . n 
A 1 159 ASN 159 155 155 ASN ASN H . n 
A 1 160 SER 160 156 156 SER SER H . n 
A 1 161 GLY 161 157 157 GLY GLY H . n 
A 1 162 ALA 162 158 158 ALA ALA H . n 
A 1 163 LEU 163 159 159 LEU LEU H . n 
A 1 164 THR 164 160 160 THR THR H . n 
A 1 165 SER 165 161 161 SER SER H . n 
A 1 166 GLY 166 162 162 GLY GLY H . n 
A 1 167 VAL 167 163 163 VAL VAL H . n 
A 1 168 HIS 168 164 164 HIS HIS H . n 
A 1 169 THR 169 165 165 THR THR H . n 
A 1 170 PHE 170 166 166 PHE PHE H . n 
A 1 171 PRO 171 167 167 PRO PRO H . n 
A 1 172 ALA 172 168 168 ALA ALA H . n 
A 1 173 VAL 173 169 169 VAL VAL H . n 
A 1 174 LEU 174 170 170 LEU LEU H . n 
A 1 175 GLN 175 171 171 GLN GLN H . n 
A 1 176 SER 176 172 172 SER SER H . n 
A 1 177 SER 177 173 173 SER SER H . n 
A 1 178 GLY 178 174 174 GLY GLY H . n 
A 1 179 LEU 179 175 175 LEU LEU H . n 
A 1 180 TYR 180 176 176 TYR TYR H . n 
A 1 181 SER 181 177 177 SER SER H . n 
A 1 182 LEU 182 178 178 LEU LEU H . n 
A 1 183 SER 183 179 179 SER SER H . n 
A 1 184 SER 184 180 180 SER SER H . n 
A 1 185 VAL 185 181 181 VAL VAL H . n 
A 1 186 VAL 186 182 182 VAL VAL H . n 
A 1 187 THR 187 183 183 THR THR H . n 
A 1 188 VAL 188 184 184 VAL VAL H . n 
A 1 189 PRO 189 185 185 PRO PRO H . n 
A 1 190 SER 190 186 186 SER SER H . n 
A 1 191 SER 191 187 187 SER SER H . n 
A 1 192 SER 192 188 188 SER SER H . n 
A 1 193 LEU 193 189 189 LEU LEU H . n 
A 1 194 GLY 194 190 190 GLY GLY H . n 
A 1 195 THR 195 191 191 THR THR H . n 
A 1 196 GLN 196 192 192 GLN GLN H . n 
A 1 197 THR 197 193 193 THR THR H . n 
A 1 198 TYR 198 194 194 TYR TYR H . n 
A 1 199 ILE 199 195 195 ILE ILE H . n 
A 1 200 CYS 200 196 196 CYS CYS H . n 
A 1 201 ASN 201 197 197 ASN ASN H . n 
A 1 202 VAL 202 198 198 VAL VAL H . n 
A 1 203 ASN 203 199 199 ASN ASN H . n 
A 1 204 HIS 204 200 200 HIS HIS H . n 
A 1 205 LYS 205 201 201 LYS LYS H . n 
A 1 206 PRO 206 202 202 PRO PRO H . n 
A 1 207 SER 207 203 203 SER SER H . n 
A 1 208 ASN 208 204 204 ASN ASN H . n 
A 1 209 THR 209 205 205 THR THR H . n 
A 1 210 LYS 210 206 206 LYS LYS H . n 
A 1 211 VAL 211 207 207 VAL VAL H . n 
A 1 212 ASP 212 208 208 ASP ASP H . n 
A 1 213 LYS 213 209 209 LYS LYS H . n 
A 1 214 LYS 214 210 210 LYS LYS H . n 
A 1 215 VAL 215 211 211 VAL VAL H . n 
A 1 216 GLU 216 212 212 GLU GLU H . n 
A 1 217 PRO 217 213 213 PRO PRO H . n 
A 1 218 LYS 218 214 214 LYS LYS H . n 
A 1 219 SER 219 215 ?   ?   ?   H . n 
A 1 220 CYS 220 216 ?   ?   ?   H . n 
A 1 221 ASP 221 217 ?   ?   ?   H . n 
A 1 222 LYS 222 218 ?   ?   ?   H . n 
A 1 223 THR 223 219 ?   ?   ?   H . n 
A 1 224 HIS 224 220 ?   ?   ?   H . n 
A 1 225 THR 225 221 ?   ?   ?   H . n 
B 2 1   ASP 1   1   1   ASP ASP L . n 
B 2 2   ILE 2   2   2   ILE ILE L . n 
B 2 3   GLN 3   3   3   GLN GLN L . n 
B 2 4   MET 4   4   4   MET MET L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   SER 9   9   9   SER SER L . n 
B 2 10  SER 10  10  10  SER SER L . n 
B 2 11  LEU 11  11  11  LEU LEU L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  VAL 15  15  15  VAL VAL L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  ASP 17  17  17  ASP ASP L . n 
B 2 18  ARG 18  18  18  ARG ARG L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  ILE 21  21  21  ILE ILE L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  GLN 27  27  27  GLN GLN L . n 
B 2 28  SER 28  27  27  SER SER L A n 
B 2 29  VAL 29  27  27  VAL VAL L B n 
B 2 30  TRP 30  28  28  TRP TRP L . n 
B 2 31  ARG 31  29  29  ARG ARG L . n 
B 2 32  ASN 32  30  30  ASN ASN L . n 
B 2 33  LYS 33  31  31  LYS LYS L . n 
B 2 34  ASN 34  32  32  ASN ASN L . n 
B 2 35  VAL 35  33  33  VAL VAL L . n 
B 2 36  ALA 36  34  34  ALA ALA L . n 
B 2 37  TRP 37  35  35  TRP TRP L . n 
B 2 38  TYR 38  36  36  TYR TYR L . n 
B 2 39  GLN 39  37  37  GLN GLN L . n 
B 2 40  GLN 40  38  38  GLN GLN L . n 
B 2 41  LYS 41  39  39  LYS LYS L . n 
B 2 42  PRO 42  40  40  PRO PRO L . n 
B 2 43  GLY 43  41  41  GLY GLY L . n 
B 2 44  LYS 44  42  42  LYS LYS L . n 
B 2 45  ALA 45  43  43  ALA ALA L . n 
B 2 46  PRO 46  44  44  PRO PRO L . n 
B 2 47  LYS 47  45  45  LYS LYS L . n 
B 2 48  ARG 48  46  46  ARG ARG L . n 
B 2 49  LEU 49  47  47  LEU LEU L . n 
B 2 50  ILE 50  48  48  ILE ILE L . n 
B 2 51  TYR 51  49  49  TYR TYR L . n 
B 2 52  ALA 52  50  50  ALA ALA L . n 
B 2 53  ILE 53  51  51  ILE ILE L . n 
B 2 54  ALA 54  52  52  ALA ALA L . n 
B 2 55  SER 55  53  53  SER SER L . n 
B 2 56  LEU 56  54  54  LEU LEU L . n 
B 2 57  TYR 57  55  55  TYR TYR L . n 
B 2 58  SER 58  56  56  SER SER L . n 
B 2 59  GLY 59  57  57  GLY GLY L . n 
B 2 60  VAL 60  58  58  VAL VAL L . n 
B 2 61  PRO 61  59  59  PRO PRO L . n 
B 2 62  SER 62  60  60  SER SER L . n 
B 2 63  ARG 63  61  61  ARG ARG L . n 
B 2 64  PHE 64  62  62  PHE PHE L . n 
B 2 65  SER 65  63  63  SER SER L . n 
B 2 66  GLY 66  64  64  GLY GLY L . n 
B 2 67  SER 67  65  65  SER SER L . n 
B 2 68  GLY 68  66  66  GLY GLY L . n 
B 2 69  SER 69  67  67  SER SER L . n 
B 2 70  GLY 70  68  68  GLY GLY L . n 
B 2 71  THR 71  69  69  THR THR L . n 
B 2 72  ASP 72  70  70  ASP ASP L . n 
B 2 73  PHE 73  71  71  PHE PHE L . n 
B 2 74  THR 74  72  72  THR THR L . n 
B 2 75  LEU 75  73  73  LEU LEU L . n 
B 2 76  THR 76  74  74  THR THR L . n 
B 2 77  ILE 77  75  75  ILE ILE L . n 
B 2 78  SER 78  76  76  SER SER L . n 
B 2 79  SER 79  77  77  SER SER L . n 
B 2 80  LEU 80  78  78  LEU LEU L . n 
B 2 81  GLN 81  79  79  GLN GLN L . n 
B 2 82  PRO 82  80  80  PRO PRO L . n 
B 2 83  GLU 83  81  81  GLU GLU L . n 
B 2 84  ASP 84  82  82  ASP ASP L . n 
B 2 85  PHE 85  83  83  PHE PHE L . n 
B 2 86  ALA 86  84  84  ALA ALA L . n 
B 2 87  THR 87  85  85  THR THR L . n 
B 2 88  TYR 88  86  86  TYR TYR L . n 
B 2 89  TYR 89  87  87  TYR TYR L . n 
B 2 90  CYS 90  88  88  CYS CYS L . n 
B 2 91  VAL 91  89  89  VAL VAL L . n 
B 2 92  GLY 92  90  90  GLY GLY L . n 
B 2 93  HIS 93  91  91  HIS HIS L . n 
B 2 94  TYR 94  92  92  TYR TYR L . n 
B 2 95  GLY 95  93  93  GLY GLY L . n 
B 2 96  SER 96  94  94  SER SER L . n 
B 2 97  GLU 97  95  95  GLU GLU L . n 
B 2 98  ASN 98  95  95  ASN ASN L A n 
B 2 99  ASP 99  95  95  ASP ASP L B n 
B 2 100 ALA 100 95  95  ALA ALA L C n 
B 2 101 TYR 101 95  95  TYR TYR L D n 
B 2 102 TYR 102 96  96  TYR TYR L . n 
B 2 103 ALA 103 97  97  ALA ALA L . n 
B 2 104 PHE 104 98  98  PHE PHE L . n 
B 2 105 GLY 105 99  99  GLY GLY L . n 
B 2 106 GLN 106 100 100 GLN GLN L . n 
B 2 107 GLY 107 101 101 GLY GLY L . n 
B 2 108 THR 108 102 102 THR THR L . n 
B 2 109 LYS 109 103 103 LYS LYS L . n 
B 2 110 VAL 110 104 104 VAL VAL L . n 
B 2 111 GLU 111 105 105 GLU GLU L . n 
B 2 112 ILE 112 106 106 ILE ILE L . n 
B 2 113 LYS 113 107 107 LYS LYS L . n 
B 2 114 ARG 114 108 108 ARG ARG L . n 
B 2 115 THR 115 109 109 THR THR L . n 
B 2 116 VAL 116 110 110 VAL VAL L . n 
B 2 117 ALA 117 111 111 ALA ALA L . n 
B 2 118 ALA 118 112 112 ALA ALA L . n 
B 2 119 PRO 119 113 113 PRO PRO L . n 
B 2 120 SER 120 114 114 SER SER L . n 
B 2 121 VAL 121 115 115 VAL VAL L . n 
B 2 122 PHE 122 116 116 PHE PHE L . n 
B 2 123 ILE 123 117 117 ILE ILE L . n 
B 2 124 PHE 124 118 118 PHE PHE L . n 
B 2 125 PRO 125 119 119 PRO PRO L . n 
B 2 126 PRO 126 120 120 PRO PRO L . n 
B 2 127 SER 127 121 121 SER SER L . n 
B 2 128 ASP 128 122 122 ASP ASP L . n 
B 2 129 GLU 129 123 123 GLU GLU L . n 
B 2 130 GLN 130 124 124 GLN GLN L . n 
B 2 131 LEU 131 125 125 LEU LEU L . n 
B 2 132 LYS 132 126 126 LYS LYS L . n 
B 2 133 SER 133 127 127 SER SER L . n 
B 2 134 GLY 134 128 128 GLY GLY L . n 
B 2 135 THR 135 129 129 THR THR L . n 
B 2 136 ALA 136 130 130 ALA ALA L . n 
B 2 137 SER 137 131 131 SER SER L . n 
B 2 138 VAL 138 132 132 VAL VAL L . n 
B 2 139 VAL 139 133 133 VAL VAL L . n 
B 2 140 CYS 140 134 134 CYS CYS L . n 
B 2 141 LEU 141 135 135 LEU LEU L . n 
B 2 142 LEU 142 136 136 LEU LEU L . n 
B 2 143 ASN 143 137 137 ASN ASN L . n 
B 2 144 ASN 144 138 138 ASN ASN L . n 
B 2 145 PHE 145 139 139 PHE PHE L . n 
B 2 146 TYR 146 140 140 TYR TYR L . n 
B 2 147 PRO 147 141 141 PRO PRO L . n 
B 2 148 ARG 148 142 142 ARG ARG L . n 
B 2 149 GLU 149 143 143 GLU GLU L . n 
B 2 150 ALA 150 144 144 ALA ALA L . n 
B 2 151 LYS 151 145 145 LYS LYS L . n 
B 2 152 VAL 152 146 146 VAL VAL L . n 
B 2 153 SER 153 147 147 SER SER L . n 
B 2 154 TRP 154 148 148 TRP TRP L . n 
B 2 155 TYR 155 149 149 TYR TYR L . n 
B 2 156 VAL 156 150 150 VAL VAL L . n 
B 2 157 ASP 157 151 151 ASP ASP L . n 
B 2 158 ASN 158 152 152 ASN ASN L . n 
B 2 159 ALA 159 153 153 ALA ALA L . n 
B 2 160 LEU 160 154 154 LEU LEU L . n 
B 2 161 GLN 161 155 155 GLN GLN L . n 
B 2 162 SER 162 156 156 SER SER L . n 
B 2 163 GLY 163 157 157 GLY GLY L . n 
B 2 164 ASN 164 158 158 ASN ASN L . n 
B 2 165 SER 165 159 159 SER SER L . n 
B 2 166 GLN 166 160 160 GLN GLN L . n 
B 2 167 GLU 167 161 161 GLU GLU L . n 
B 2 168 SER 168 162 162 SER SER L . n 
B 2 169 VAL 169 163 163 VAL VAL L . n 
B 2 170 THR 170 164 164 THR THR L . n 
B 2 171 GLU 171 165 165 GLU GLU L . n 
B 2 172 GLN 172 166 166 GLN GLN L . n 
B 2 173 ASP 173 167 167 ASP ASP L . n 
B 2 174 SER 174 168 168 SER SER L . n 
B 2 175 LYS 175 169 169 LYS LYS L . n 
B 2 176 ASP 176 170 170 ASP ASP L . n 
B 2 177 SER 177 171 171 SER SER L . n 
B 2 178 THR 178 172 172 THR THR L . n 
B 2 179 TYR 179 173 173 TYR TYR L . n 
B 2 180 SER 180 174 174 SER SER L . n 
B 2 181 LEU 181 175 175 LEU LEU L . n 
B 2 182 SER 182 176 176 SER SER L . n 
B 2 183 SER 183 177 177 SER SER L . n 
B 2 184 THR 184 178 178 THR THR L . n 
B 2 185 LEU 185 179 179 LEU LEU L . n 
B 2 186 THR 186 180 180 THR THR L . n 
B 2 187 LEU 187 181 181 LEU LEU L . n 
B 2 188 SER 188 182 182 SER SER L . n 
B 2 189 LYS 189 183 183 LYS LYS L . n 
B 2 190 ALA 190 184 184 ALA ALA L . n 
B 2 191 ASP 191 185 185 ASP ASP L . n 
B 2 192 TYR 192 186 186 TYR TYR L . n 
B 2 193 GLU 193 187 187 GLU GLU L . n 
B 2 194 LYS 194 188 188 LYS LYS L . n 
B 2 195 HIS 195 189 189 HIS HIS L . n 
B 2 196 LYS 196 190 190 LYS LYS L . n 
B 2 197 VAL 197 191 191 VAL VAL L . n 
B 2 198 TYR 198 192 192 TYR TYR L . n 
B 2 199 ALA 199 193 193 ALA ALA L . n 
B 2 200 CYS 200 194 194 CYS CYS L . n 
B 2 201 GLU 201 195 195 GLU GLU L . n 
B 2 202 VAL 202 196 196 VAL VAL L . n 
B 2 203 THR 203 197 197 THR THR L . n 
B 2 204 GLN 204 198 198 GLN GLN L . n 
B 2 205 GLY 205 199 199 GLY GLY L . n 
B 2 206 THR 206 200 200 THR THR L . n 
B 2 207 THR 207 201 201 THR THR L . n 
B 2 208 SER 208 202 202 SER SER L . n 
B 2 209 VAL 209 203 203 VAL VAL L . n 
B 2 210 THR 210 204 204 THR THR L . n 
B 2 211 LYS 211 205 205 LYS LYS L . n 
B 2 212 SER 212 206 206 SER SER L . n 
B 2 213 PHE 213 207 207 PHE PHE L . n 
B 2 214 ASN 214 208 208 ASN ASN L . n 
B 2 215 ARG 215 209 209 ARG ARG L . n 
B 2 216 GLY 216 210 210 GLY GLY L . n 
B 2 217 GLU 217 211 211 GLU GLU L . n 
B 2 218 CYS 218 212 212 CYS CYS L . n 
C 1 1   GLU 1   1   ?   ?   ?   A . n 
C 1 2   VAL 2   2   2   VAL VAL A . n 
C 1 3   GLN 3   3   3   GLN GLN A . n 
C 1 4   LEU 4   4   4   LEU LEU A . n 
C 1 5   VAL 5   5   5   VAL VAL A . n 
C 1 6   GLU 6   6   6   GLU GLU A . n 
C 1 7   SER 7   7   7   SER SER A . n 
C 1 8   GLY 8   8   8   GLY GLY A . n 
C 1 9   GLY 9   9   9   GLY GLY A . n 
C 1 10  GLY 10  10  10  GLY GLY A . n 
C 1 11  LEU 11  11  11  LEU LEU A . n 
C 1 12  VAL 12  12  12  VAL VAL A . n 
C 1 13  GLN 13  13  13  GLN GLN A . n 
C 1 14  PRO 14  14  14  PRO PRO A . n 
C 1 15  GLY 15  15  15  GLY GLY A . n 
C 1 16  GLY 16  16  16  GLY GLY A . n 
C 1 17  SER 17  17  17  SER SER A . n 
C 1 18  LEU 18  18  18  LEU LEU A . n 
C 1 19  ARG 19  19  19  ARG ARG A . n 
C 1 20  LEU 20  20  20  LEU LEU A . n 
C 1 21  SER 21  21  21  SER SER A . n 
C 1 22  CYS 22  22  22  CYS CYS A . n 
C 1 23  THR 23  23  23  THR THR A . n 
C 1 24  ALA 24  24  24  ALA ALA A . n 
C 1 25  SER 25  25  25  SER SER A . n 
C 1 26  GLY 26  26  26  GLY GLY A . n 
C 1 27  PHE 27  27  27  PHE PHE A . n 
C 1 28  SER 28  28  28  SER SER A . n 
C 1 29  ILE 29  29  29  ILE ILE A . n 
C 1 30  ASP 30  30  30  ASP ASP A . n 
C 1 31  SER 31  31  31  SER SER A . n 
C 1 32  TYR 32  32  32  TYR TYR A . n 
C 1 33  GLY 33  33  33  GLY GLY A . n 
C 1 34  PHE 34  34  34  PHE PHE A . n 
C 1 35  SER 35  35  35  SER SER A . n 
C 1 36  TRP 36  36  36  TRP TRP A . n 
C 1 37  VAL 37  37  37  VAL VAL A . n 
C 1 38  ARG 38  38  38  ARG ARG A . n 
C 1 39  GLN 39  39  39  GLN GLN A . n 
C 1 40  ALA 40  40  40  ALA ALA A . n 
C 1 41  PRO 41  41  41  PRO PRO A . n 
C 1 42  GLY 42  42  42  GLY GLY A . n 
C 1 43  LYS 43  43  43  LYS LYS A . n 
C 1 44  GLY 44  44  44  GLY GLY A . n 
C 1 45  LEU 45  45  45  LEU LEU A . n 
C 1 46  GLU 46  46  46  GLU GLU A . n 
C 1 47  HIS 47  47  47  HIS HIS A . n 
C 1 48  ILE 48  48  48  ILE ILE A . n 
C 1 49  GLY 49  49  49  GLY GLY A . n 
C 1 50  TYR 50  50  50  TYR TYR A . n 
C 1 51  LEU 51  51  51  LEU LEU A . n 
C 1 52  THR 52  52  52  THR THR A . n 
C 1 53  ALA 53  53  53  ALA ALA A . n 
C 1 54  GLY 54  54  54  GLY GLY A . n 
C 1 55  GLY 55  55  55  GLY GLY A . n 
C 1 56  ARG 56  56  56  ARG ARG A . n 
C 1 57  ALA 57  57  57  ALA ALA A . n 
C 1 58  PHE 58  58  58  PHE PHE A . n 
C 1 59  TYR 59  59  59  TYR TYR A . n 
C 1 60  ALA 60  60  60  ALA ALA A . n 
C 1 61  SER 61  61  61  SER SER A . n 
C 1 62  TRP 62  62  62  TRP TRP A . n 
C 1 63  ALA 63  63  63  ALA ALA A . n 
C 1 64  LYS 64  64  64  LYS LYS A . n 
C 1 65  SER 65  65  65  SER SER A . n 
C 1 66  ARG 66  66  66  ARG ARG A . n 
C 1 67  SER 67  67  67  SER SER A . n 
C 1 68  THR 68  68  68  THR THR A . n 
C 1 69  ILE 69  69  69  ILE ILE A . n 
C 1 70  THR 70  70  70  THR THR A . n 
C 1 71  ARG 71  71  71  ARG ARG A . n 
C 1 72  ASN 72  72  72  ASN ASN A . n 
C 1 73  THR 73  73  73  THR THR A . n 
C 1 74  ASN 74  74  74  ASN ASN A . n 
C 1 75  GLU 75  75  75  GLU GLU A . n 
C 1 76  ASN 76  76  76  ASN ASN A . n 
C 1 77  THR 77  77  77  THR THR A . n 
C 1 78  VAL 78  78  78  VAL VAL A . n 
C 1 79  THR 79  79  79  THR THR A . n 
C 1 80  LEU 80  80  80  LEU LEU A . n 
C 1 81  LYS 81  81  81  LYS LYS A . n 
C 1 82  MET 82  82  82  MET MET A . n 
C 1 83  ASN 83  82  82  ASN ASN A A n 
C 1 84  SER 84  82  82  SER SER A B n 
C 1 85  LEU 85  82  82  LEU LEU A C n 
C 1 86  ARG 86  83  83  ARG ARG A . n 
C 1 87  ALA 87  84  84  ALA ALA A . n 
C 1 88  GLU 88  85  85  GLU GLU A . n 
C 1 89  ASP 89  86  86  ASP ASP A . n 
C 1 90  THR 90  87  87  THR THR A . n 
C 1 91  ALA 91  88  88  ALA ALA A . n 
C 1 92  VAL 92  89  89  VAL VAL A . n 
C 1 93  TYR 93  90  90  TYR TYR A . n 
C 1 94  TYR 94  91  91  TYR TYR A . n 
C 1 95  CYS 95  92  92  CYS CYS A . n 
C 1 96  ALA 96  93  93  ALA ALA A . n 
C 1 97  LYS 97  94  94  LYS LYS A . n 
C 1 98  LEU 98  95  95  LEU LEU A . n 
C 1 99  GLY 99  96  96  GLY GLY A . n 
C 1 100 SER 100 97  97  SER SER A . n 
C 1 101 GLY 101 98  98  GLY GLY A . n 
C 1 102 ASN 102 99  99  ASN ASN A . n 
C 1 103 PRO 103 100 100 PRO PRO A . n 
C 1 104 VAL 104 100 100 VAL VAL A A n 
C 1 105 ALA 105 101 101 ALA ALA A . n 
C 1 106 ILE 106 102 102 ILE ILE A . n 
C 1 107 TRP 107 103 103 TRP TRP A . n 
C 1 108 GLY 108 104 104 GLY GLY A . n 
C 1 109 GLN 109 105 105 GLN GLN A . n 
C 1 110 GLY 110 106 106 GLY GLY A . n 
C 1 111 THR 111 107 107 THR THR A . n 
C 1 112 LEU 112 108 108 LEU LEU A . n 
C 1 113 VAL 113 109 109 VAL VAL A . n 
C 1 114 THR 114 110 110 THR THR A . n 
C 1 115 VAL 115 111 111 VAL VAL A . n 
C 1 116 SER 116 112 112 SER SER A . n 
C 1 117 SER 117 113 113 SER SER A . n 
C 1 118 ALA 118 114 114 ALA ALA A . n 
C 1 119 SER 119 115 115 SER SER A . n 
C 1 120 THR 120 116 116 THR THR A . n 
C 1 121 LYS 121 117 117 LYS LYS A . n 
C 1 122 GLY 122 118 118 GLY GLY A . n 
C 1 123 PRO 123 119 119 PRO PRO A . n 
C 1 124 SER 124 120 120 SER SER A . n 
C 1 125 VAL 125 121 121 VAL VAL A . n 
C 1 126 PHE 126 122 122 PHE PHE A . n 
C 1 127 PRO 127 123 123 PRO PRO A . n 
C 1 128 LEU 128 124 124 LEU LEU A . n 
C 1 129 ALA 129 125 125 ALA ALA A . n 
C 1 130 PRO 130 126 126 PRO PRO A . n 
C 1 131 SER 131 127 127 SER SER A . n 
C 1 132 SER 132 128 128 SER SER A . n 
C 1 133 LYS 133 129 129 LYS LYS A . n 
C 1 134 SER 134 130 130 SER SER A . n 
C 1 135 THR 135 131 131 THR THR A . n 
C 1 136 SER 136 132 132 SER SER A . n 
C 1 137 GLY 137 133 133 GLY GLY A . n 
C 1 138 GLY 138 134 134 GLY GLY A . n 
C 1 139 THR 139 135 135 THR THR A . n 
C 1 140 ALA 140 136 136 ALA ALA A . n 
C 1 141 ALA 141 137 137 ALA ALA A . n 
C 1 142 LEU 142 138 138 LEU LEU A . n 
C 1 143 GLY 143 139 139 GLY GLY A . n 
C 1 144 CYS 144 140 140 CYS CYS A . n 
C 1 145 LEU 145 141 141 LEU LEU A . n 
C 1 146 VAL 146 142 142 VAL VAL A . n 
C 1 147 LYS 147 143 143 LYS LYS A . n 
C 1 148 ASP 148 144 144 ASP ASP A . n 
C 1 149 TYR 149 145 145 TYR TYR A . n 
C 1 150 PHE 150 146 146 PHE PHE A . n 
C 1 151 PRO 151 147 147 PRO PRO A . n 
C 1 152 GLU 152 148 148 GLU GLU A . n 
C 1 153 PRO 153 149 149 PRO PRO A . n 
C 1 154 VAL 154 150 150 VAL VAL A . n 
C 1 155 THR 155 151 151 THR THR A . n 
C 1 156 VAL 156 152 152 VAL VAL A . n 
C 1 157 SER 157 153 153 SER SER A . n 
C 1 158 TRP 158 154 154 TRP TRP A . n 
C 1 159 ASN 159 155 155 ASN ASN A . n 
C 1 160 SER 160 156 156 SER SER A . n 
C 1 161 GLY 161 157 157 GLY GLY A . n 
C 1 162 ALA 162 158 158 ALA ALA A . n 
C 1 163 LEU 163 159 159 LEU LEU A . n 
C 1 164 THR 164 160 160 THR THR A . n 
C 1 165 SER 165 161 161 SER SER A . n 
C 1 166 GLY 166 162 162 GLY GLY A . n 
C 1 167 VAL 167 163 163 VAL VAL A . n 
C 1 168 HIS 168 164 164 HIS HIS A . n 
C 1 169 THR 169 165 165 THR THR A . n 
C 1 170 PHE 170 166 166 PHE PHE A . n 
C 1 171 PRO 171 167 167 PRO PRO A . n 
C 1 172 ALA 172 168 168 ALA ALA A . n 
C 1 173 VAL 173 169 169 VAL VAL A . n 
C 1 174 LEU 174 170 170 LEU LEU A . n 
C 1 175 GLN 175 171 171 GLN GLN A . n 
C 1 176 SER 176 172 172 SER SER A . n 
C 1 177 SER 177 173 173 SER SER A . n 
C 1 178 GLY 178 174 174 GLY GLY A . n 
C 1 179 LEU 179 175 175 LEU LEU A . n 
C 1 180 TYR 180 176 176 TYR TYR A . n 
C 1 181 SER 181 177 177 SER SER A . n 
C 1 182 LEU 182 178 178 LEU LEU A . n 
C 1 183 SER 183 179 179 SER SER A . n 
C 1 184 SER 184 180 180 SER SER A . n 
C 1 185 VAL 185 181 181 VAL VAL A . n 
C 1 186 VAL 186 182 182 VAL VAL A . n 
C 1 187 THR 187 183 183 THR THR A . n 
C 1 188 VAL 188 184 184 VAL VAL A . n 
C 1 189 PRO 189 185 185 PRO PRO A . n 
C 1 190 SER 190 186 186 SER SER A . n 
C 1 191 SER 191 187 187 SER SER A . n 
C 1 192 SER 192 188 188 SER SER A . n 
C 1 193 LEU 193 189 189 LEU LEU A . n 
C 1 194 GLY 194 190 190 GLY GLY A . n 
C 1 195 THR 195 191 191 THR THR A . n 
C 1 196 GLN 196 192 192 GLN GLN A . n 
C 1 197 THR 197 193 193 THR THR A . n 
C 1 198 TYR 198 194 194 TYR TYR A . n 
C 1 199 ILE 199 195 195 ILE ILE A . n 
C 1 200 CYS 200 196 196 CYS CYS A . n 
C 1 201 ASN 201 197 197 ASN ASN A . n 
C 1 202 VAL 202 198 198 VAL VAL A . n 
C 1 203 ASN 203 199 199 ASN ASN A . n 
C 1 204 HIS 204 200 200 HIS HIS A . n 
C 1 205 LYS 205 201 201 LYS LYS A . n 
C 1 206 PRO 206 202 202 PRO PRO A . n 
C 1 207 SER 207 203 203 SER SER A . n 
C 1 208 ASN 208 204 204 ASN ASN A . n 
C 1 209 THR 209 205 205 THR THR A . n 
C 1 210 LYS 210 206 206 LYS LYS A . n 
C 1 211 VAL 211 207 207 VAL VAL A . n 
C 1 212 ASP 212 208 208 ASP ASP A . n 
C 1 213 LYS 213 209 209 LYS LYS A . n 
C 1 214 LYS 214 210 210 LYS LYS A . n 
C 1 215 VAL 215 211 211 VAL VAL A . n 
C 1 216 GLU 216 212 212 GLU GLU A . n 
C 1 217 PRO 217 213 213 PRO PRO A . n 
C 1 218 LYS 218 214 214 LYS LYS A . n 
C 1 219 SER 219 215 ?   ?   ?   A . n 
C 1 220 CYS 220 216 ?   ?   ?   A . n 
C 1 221 ASP 221 217 ?   ?   ?   A . n 
C 1 222 LYS 222 218 ?   ?   ?   A . n 
C 1 223 THR 223 219 ?   ?   ?   A . n 
C 1 224 HIS 224 220 ?   ?   ?   A . n 
C 1 225 THR 225 221 ?   ?   ?   A . n 
D 2 1   ASP 1   1   1   ASP ASP B . n 
D 2 2   ILE 2   2   2   ILE ILE B . n 
D 2 3   GLN 3   3   3   GLN GLN B . n 
D 2 4   MET 4   4   4   MET MET B . n 
D 2 5   THR 5   5   5   THR THR B . n 
D 2 6   GLN 6   6   6   GLN GLN B . n 
D 2 7   SER 7   7   7   SER SER B . n 
D 2 8   PRO 8   8   8   PRO PRO B . n 
D 2 9   SER 9   9   9   SER SER B . n 
D 2 10  SER 10  10  10  SER SER B . n 
D 2 11  LEU 11  11  11  LEU LEU B . n 
D 2 12  SER 12  12  12  SER SER B . n 
D 2 13  ALA 13  13  13  ALA ALA B . n 
D 2 14  SER 14  14  14  SER SER B . n 
D 2 15  VAL 15  15  15  VAL VAL B . n 
D 2 16  GLY 16  16  16  GLY GLY B . n 
D 2 17  ASP 17  17  17  ASP ASP B . n 
D 2 18  ARG 18  18  18  ARG ARG B . n 
D 2 19  VAL 19  19  19  VAL VAL B . n 
D 2 20  THR 20  20  20  THR THR B . n 
D 2 21  ILE 21  21  21  ILE ILE B . n 
D 2 22  THR 22  22  22  THR THR B . n 
D 2 23  CYS 23  23  23  CYS CYS B . n 
D 2 24  ARG 24  24  24  ARG ARG B . n 
D 2 25  ALA 25  25  25  ALA ALA B . n 
D 2 26  SER 26  26  26  SER SER B . n 
D 2 27  GLN 27  27  27  GLN GLN B . n 
D 2 28  SER 28  27  27  SER SER B A n 
D 2 29  VAL 29  27  27  VAL VAL B B n 
D 2 30  TRP 30  28  28  TRP TRP B . n 
D 2 31  ARG 31  29  29  ARG ARG B . n 
D 2 32  ASN 32  30  30  ASN ASN B . n 
D 2 33  LYS 33  31  31  LYS LYS B . n 
D 2 34  ASN 34  32  32  ASN ASN B . n 
D 2 35  VAL 35  33  33  VAL VAL B . n 
D 2 36  ALA 36  34  34  ALA ALA B . n 
D 2 37  TRP 37  35  35  TRP TRP B . n 
D 2 38  TYR 38  36  36  TYR TYR B . n 
D 2 39  GLN 39  37  37  GLN GLN B . n 
D 2 40  GLN 40  38  38  GLN GLN B . n 
D 2 41  LYS 41  39  39  LYS LYS B . n 
D 2 42  PRO 42  40  40  PRO PRO B . n 
D 2 43  GLY 43  41  41  GLY GLY B . n 
D 2 44  LYS 44  42  42  LYS LYS B . n 
D 2 45  ALA 45  43  43  ALA ALA B . n 
D 2 46  PRO 46  44  44  PRO PRO B . n 
D 2 47  LYS 47  45  45  LYS LYS B . n 
D 2 48  ARG 48  46  46  ARG ARG B . n 
D 2 49  LEU 49  47  47  LEU LEU B . n 
D 2 50  ILE 50  48  48  ILE ILE B . n 
D 2 51  TYR 51  49  49  TYR TYR B . n 
D 2 52  ALA 52  50  50  ALA ALA B . n 
D 2 53  ILE 53  51  51  ILE ILE B . n 
D 2 54  ALA 54  52  52  ALA ALA B . n 
D 2 55  SER 55  53  53  SER SER B . n 
D 2 56  LEU 56  54  54  LEU LEU B . n 
D 2 57  TYR 57  55  55  TYR TYR B . n 
D 2 58  SER 58  56  56  SER SER B . n 
D 2 59  GLY 59  57  57  GLY GLY B . n 
D 2 60  VAL 60  58  58  VAL VAL B . n 
D 2 61  PRO 61  59  59  PRO PRO B . n 
D 2 62  SER 62  60  60  SER SER B . n 
D 2 63  ARG 63  61  61  ARG ARG B . n 
D 2 64  PHE 64  62  62  PHE PHE B . n 
D 2 65  SER 65  63  63  SER SER B . n 
D 2 66  GLY 66  64  64  GLY GLY B . n 
D 2 67  SER 67  65  65  SER SER B . n 
D 2 68  GLY 68  66  66  GLY GLY B . n 
D 2 69  SER 69  67  67  SER SER B . n 
D 2 70  GLY 70  68  68  GLY GLY B . n 
D 2 71  THR 71  69  69  THR THR B . n 
D 2 72  ASP 72  70  70  ASP ASP B . n 
D 2 73  PHE 73  71  71  PHE PHE B . n 
D 2 74  THR 74  72  72  THR THR B . n 
D 2 75  LEU 75  73  73  LEU LEU B . n 
D 2 76  THR 76  74  74  THR THR B . n 
D 2 77  ILE 77  75  75  ILE ILE B . n 
D 2 78  SER 78  76  76  SER SER B . n 
D 2 79  SER 79  77  77  SER SER B . n 
D 2 80  LEU 80  78  78  LEU LEU B . n 
D 2 81  GLN 81  79  79  GLN GLN B . n 
D 2 82  PRO 82  80  80  PRO PRO B . n 
D 2 83  GLU 83  81  81  GLU GLU B . n 
D 2 84  ASP 84  82  82  ASP ASP B . n 
D 2 85  PHE 85  83  83  PHE PHE B . n 
D 2 86  ALA 86  84  84  ALA ALA B . n 
D 2 87  THR 87  85  85  THR THR B . n 
D 2 88  TYR 88  86  86  TYR TYR B . n 
D 2 89  TYR 89  87  87  TYR TYR B . n 
D 2 90  CYS 90  88  88  CYS CYS B . n 
D 2 91  VAL 91  89  89  VAL VAL B . n 
D 2 92  GLY 92  90  90  GLY GLY B . n 
D 2 93  HIS 93  91  91  HIS HIS B . n 
D 2 94  TYR 94  92  92  TYR TYR B . n 
D 2 95  GLY 95  93  93  GLY GLY B . n 
D 2 96  SER 96  94  94  SER SER B . n 
D 2 97  GLU 97  95  95  GLU GLU B . n 
D 2 98  ASN 98  95  95  ASN ASN B A n 
D 2 99  ASP 99  95  95  ASP ASP B B n 
D 2 100 ALA 100 95  95  ALA ALA B C n 
D 2 101 TYR 101 95  95  TYR TYR B D n 
D 2 102 TYR 102 96  96  TYR TYR B . n 
D 2 103 ALA 103 97  97  ALA ALA B . n 
D 2 104 PHE 104 98  98  PHE PHE B . n 
D 2 105 GLY 105 99  99  GLY GLY B . n 
D 2 106 GLN 106 100 100 GLN GLN B . n 
D 2 107 GLY 107 101 101 GLY GLY B . n 
D 2 108 THR 108 102 102 THR THR B . n 
D 2 109 LYS 109 103 103 LYS LYS B . n 
D 2 110 VAL 110 104 104 VAL VAL B . n 
D 2 111 GLU 111 105 105 GLU GLU B . n 
D 2 112 ILE 112 106 106 ILE ILE B . n 
D 2 113 LYS 113 107 107 LYS LYS B . n 
D 2 114 ARG 114 108 108 ARG ARG B . n 
D 2 115 THR 115 109 109 THR THR B . n 
D 2 116 VAL 116 110 110 VAL VAL B . n 
D 2 117 ALA 117 111 111 ALA ALA B . n 
D 2 118 ALA 118 112 112 ALA ALA B . n 
D 2 119 PRO 119 113 113 PRO PRO B . n 
D 2 120 SER 120 114 114 SER SER B . n 
D 2 121 VAL 121 115 115 VAL VAL B . n 
D 2 122 PHE 122 116 116 PHE PHE B . n 
D 2 123 ILE 123 117 117 ILE ILE B . n 
D 2 124 PHE 124 118 118 PHE PHE B . n 
D 2 125 PRO 125 119 119 PRO PRO B . n 
D 2 126 PRO 126 120 120 PRO PRO B . n 
D 2 127 SER 127 121 121 SER SER B . n 
D 2 128 ASP 128 122 122 ASP ASP B . n 
D 2 129 GLU 129 123 123 GLU GLU B . n 
D 2 130 GLN 130 124 124 GLN GLN B . n 
D 2 131 LEU 131 125 125 LEU LEU B . n 
D 2 132 LYS 132 126 126 LYS LYS B . n 
D 2 133 SER 133 127 127 SER SER B . n 
D 2 134 GLY 134 128 128 GLY GLY B . n 
D 2 135 THR 135 129 129 THR THR B . n 
D 2 136 ALA 136 130 130 ALA ALA B . n 
D 2 137 SER 137 131 131 SER SER B . n 
D 2 138 VAL 138 132 132 VAL VAL B . n 
D 2 139 VAL 139 133 133 VAL VAL B . n 
D 2 140 CYS 140 134 134 CYS CYS B . n 
D 2 141 LEU 141 135 135 LEU LEU B . n 
D 2 142 LEU 142 136 136 LEU LEU B . n 
D 2 143 ASN 143 137 137 ASN ASN B . n 
D 2 144 ASN 144 138 138 ASN ASN B . n 
D 2 145 PHE 145 139 139 PHE PHE B . n 
D 2 146 TYR 146 140 140 TYR TYR B . n 
D 2 147 PRO 147 141 141 PRO PRO B . n 
D 2 148 ARG 148 142 142 ARG ARG B . n 
D 2 149 GLU 149 143 143 GLU GLU B . n 
D 2 150 ALA 150 144 144 ALA ALA B . n 
D 2 151 LYS 151 145 145 LYS LYS B . n 
D 2 152 VAL 152 146 146 VAL VAL B . n 
D 2 153 SER 153 147 147 SER SER B . n 
D 2 154 TRP 154 148 148 TRP TRP B . n 
D 2 155 TYR 155 149 149 TYR TYR B . n 
D 2 156 VAL 156 150 150 VAL VAL B . n 
D 2 157 ASP 157 151 151 ASP ASP B . n 
D 2 158 ASN 158 152 152 ASN ASN B . n 
D 2 159 ALA 159 153 153 ALA ALA B . n 
D 2 160 LEU 160 154 154 LEU LEU B . n 
D 2 161 GLN 161 155 155 GLN GLN B . n 
D 2 162 SER 162 156 156 SER SER B . n 
D 2 163 GLY 163 157 157 GLY GLY B . n 
D 2 164 ASN 164 158 158 ASN ASN B . n 
D 2 165 SER 165 159 159 SER SER B . n 
D 2 166 GLN 166 160 160 GLN GLN B . n 
D 2 167 GLU 167 161 161 GLU GLU B . n 
D 2 168 SER 168 162 162 SER SER B . n 
D 2 169 VAL 169 163 163 VAL VAL B . n 
D 2 170 THR 170 164 164 THR THR B . n 
D 2 171 GLU 171 165 165 GLU GLU B . n 
D 2 172 GLN 172 166 166 GLN GLN B . n 
D 2 173 ASP 173 167 167 ASP ASP B . n 
D 2 174 SER 174 168 168 SER SER B . n 
D 2 175 LYS 175 169 169 LYS LYS B . n 
D 2 176 ASP 176 170 170 ASP ASP B . n 
D 2 177 SER 177 171 171 SER SER B . n 
D 2 178 THR 178 172 172 THR THR B . n 
D 2 179 TYR 179 173 173 TYR TYR B . n 
D 2 180 SER 180 174 174 SER SER B . n 
D 2 181 LEU 181 175 175 LEU LEU B . n 
D 2 182 SER 182 176 176 SER SER B . n 
D 2 183 SER 183 177 177 SER SER B . n 
D 2 184 THR 184 178 178 THR THR B . n 
D 2 185 LEU 185 179 179 LEU LEU B . n 
D 2 186 THR 186 180 180 THR THR B . n 
D 2 187 LEU 187 181 181 LEU LEU B . n 
D 2 188 SER 188 182 182 SER SER B . n 
D 2 189 LYS 189 183 183 LYS LYS B . n 
D 2 190 ALA 190 184 184 ALA ALA B . n 
D 2 191 ASP 191 185 185 ASP ASP B . n 
D 2 192 TYR 192 186 186 TYR TYR B . n 
D 2 193 GLU 193 187 187 GLU GLU B . n 
D 2 194 LYS 194 188 188 LYS LYS B . n 
D 2 195 HIS 195 189 189 HIS HIS B . n 
D 2 196 LYS 196 190 190 LYS LYS B . n 
D 2 197 VAL 197 191 191 VAL VAL B . n 
D 2 198 TYR 198 192 192 TYR TYR B . n 
D 2 199 ALA 199 193 193 ALA ALA B . n 
D 2 200 CYS 200 194 194 CYS CYS B . n 
D 2 201 GLU 201 195 195 GLU GLU B . n 
D 2 202 VAL 202 196 196 VAL VAL B . n 
D 2 203 THR 203 197 197 THR THR B . n 
D 2 204 GLN 204 198 198 GLN GLN B . n 
D 2 205 GLY 205 199 199 GLY GLY B . n 
D 2 206 THR 206 200 200 THR THR B . n 
D 2 207 THR 207 201 201 THR THR B . n 
D 2 208 SER 208 202 202 SER SER B . n 
D 2 209 VAL 209 203 203 VAL VAL B . n 
D 2 210 THR 210 204 204 THR THR B . n 
D 2 211 LYS 211 205 205 LYS LYS B . n 
D 2 212 SER 212 206 206 SER SER B . n 
D 2 213 PHE 213 207 207 PHE PHE B . n 
D 2 214 ASN 214 208 208 ASN ASN B . n 
D 2 215 ARG 215 209 209 ARG ARG B . n 
D 2 216 GLY 216 210 210 GLY GLY B . n 
D 2 217 GLU 217 211 211 GLU GLU B . n 
D 2 218 CYS 218 212 212 CYS CYS B . n 
E 3 1   ALA 1   1   ?   ?   ?   C . n 
E 3 2   GLY 2   2   ?   ?   ?   C . n 
E 3 3   ALA 3   3   ?   ?   ?   C . n 
E 3 4   GLY 4   4   4   GLY GLY C . n 
E 3 5   UKD 5   5   5   UKD HP3 C . n 
E 3 6   ALA 6   6   6   ALA ALA C . n 
E 3 7   GLY 7   7   7   GLY GLY C . n 
E 3 8   ALA 8   8   8   ALA ALA C . n 
E 3 9   GLY 9   9   ?   ?   ?   C . n 
F 3 1   ALA 1   1   ?   ?   ?   D . n 
F 3 2   GLY 2   2   ?   ?   ?   D . n 
F 3 3   ALA 3   3   3   ALA ALA D . n 
F 3 4   GLY 4   4   4   GLY GLY D . n 
F 3 5   UKD 5   5   5   UKD HP3 D . n 
F 3 6   ALA 6   6   6   ALA ALA D . n 
F 3 7   GLY 7   7   7   GLY GLY D . n 
F 3 8   ALA 8   8   ?   ?   ?   D . n 
F 3 9   GLY 9   9   ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        UKD 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   UKD 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
G 4 EDO 1  301 301 EDO EDO H . 
H 5 HOH 1  401 229 HOH HOH H . 
H 5 HOH 2  402 233 HOH HOH H . 
H 5 HOH 3  403 14  HOH HOH H . 
H 5 HOH 4  404 224 HOH HOH H . 
H 5 HOH 5  405 27  HOH HOH H . 
H 5 HOH 6  406 67  HOH HOH H . 
H 5 HOH 7  407 66  HOH HOH H . 
H 5 HOH 8  408 129 HOH HOH H . 
H 5 HOH 9  409 65  HOH HOH H . 
H 5 HOH 10 410 124 HOH HOH H . 
H 5 HOH 11 411 16  HOH HOH H . 
H 5 HOH 12 412 4   HOH HOH H . 
H 5 HOH 13 413 134 HOH HOH H . 
H 5 HOH 14 414 123 HOH HOH H . 
H 5 HOH 15 415 18  HOH HOH H . 
H 5 HOH 16 416 133 HOH HOH H . 
H 5 HOH 17 417 56  HOH HOH H . 
H 5 HOH 18 418 116 HOH HOH H . 
H 5 HOH 19 419 197 HOH HOH H . 
H 5 HOH 20 420 93  HOH HOH H . 
H 5 HOH 21 421 159 HOH HOH H . 
H 5 HOH 22 422 200 HOH HOH H . 
H 5 HOH 23 423 195 HOH HOH H . 
H 5 HOH 24 424 64  HOH HOH H . 
H 5 HOH 25 425 38  HOH HOH H . 
H 5 HOH 26 426 63  HOH HOH H . 
H 5 HOH 27 427 144 HOH HOH H . 
H 5 HOH 28 428 199 HOH HOH H . 
H 5 HOH 29 429 230 HOH HOH H . 
H 5 HOH 30 430 47  HOH HOH H . 
H 5 HOH 31 431 102 HOH HOH H . 
H 5 HOH 32 432 43  HOH HOH H . 
H 5 HOH 33 433 50  HOH HOH H . 
H 5 HOH 34 434 145 HOH HOH H . 
H 5 HOH 35 435 111 HOH HOH H . 
H 5 HOH 36 436 190 HOH HOH H . 
H 5 HOH 37 437 85  HOH HOH H . 
H 5 HOH 38 438 161 HOH HOH H . 
H 5 HOH 39 439 28  HOH HOH H . 
H 5 HOH 40 440 23  HOH HOH H . 
H 5 HOH 41 441 152 HOH HOH H . 
H 5 HOH 42 442 131 HOH HOH H . 
H 5 HOH 43 443 212 HOH HOH H . 
H 5 HOH 44 444 97  HOH HOH H . 
H 5 HOH 45 445 49  HOH HOH H . 
H 5 HOH 46 446 13  HOH HOH H . 
H 5 HOH 47 447 71  HOH HOH H . 
H 5 HOH 48 448 92  HOH HOH H . 
H 5 HOH 49 449 149 HOH HOH H . 
H 5 HOH 50 450 211 HOH HOH H . 
H 5 HOH 51 451 119 HOH HOH H . 
H 5 HOH 52 452 69  HOH HOH H . 
H 5 HOH 53 453 78  HOH HOH H . 
H 5 HOH 54 454 192 HOH HOH H . 
H 5 HOH 55 455 225 HOH HOH H . 
H 5 HOH 56 456 140 HOH HOH H . 
H 5 HOH 57 457 96  HOH HOH H . 
H 5 HOH 58 458 205 HOH HOH H . 
H 5 HOH 59 459 204 HOH HOH H . 
H 5 HOH 60 460 186 HOH HOH H . 
H 5 HOH 61 461 185 HOH HOH H . 
I 5 HOH 1  301 54  HOH HOH L . 
I 5 HOH 2  302 17  HOH HOH L . 
I 5 HOH 3  303 178 HOH HOH L . 
I 5 HOH 4  304 60  HOH HOH L . 
I 5 HOH 5  305 73  HOH HOH L . 
I 5 HOH 6  306 127 HOH HOH L . 
I 5 HOH 7  307 148 HOH HOH L . 
I 5 HOH 8  308 61  HOH HOH L . 
I 5 HOH 9  309 176 HOH HOH L . 
I 5 HOH 10 310 98  HOH HOH L . 
I 5 HOH 11 311 10  HOH HOH L . 
I 5 HOH 12 312 22  HOH HOH L . 
I 5 HOH 13 313 221 HOH HOH L . 
I 5 HOH 14 314 53  HOH HOH L . 
I 5 HOH 15 315 6   HOH HOH L . 
I 5 HOH 16 316 57  HOH HOH L . 
I 5 HOH 17 317 32  HOH HOH L . 
I 5 HOH 18 318 30  HOH HOH L . 
I 5 HOH 19 319 79  HOH HOH L . 
I 5 HOH 20 320 5   HOH HOH L . 
I 5 HOH 21 321 33  HOH HOH L . 
I 5 HOH 22 322 222 HOH HOH L . 
I 5 HOH 23 323 181 HOH HOH L . 
I 5 HOH 24 324 35  HOH HOH L . 
I 5 HOH 25 325 76  HOH HOH L . 
I 5 HOH 26 326 59  HOH HOH L . 
I 5 HOH 27 327 177 HOH HOH L . 
I 5 HOH 28 328 113 HOH HOH L . 
I 5 HOH 29 329 37  HOH HOH L . 
I 5 HOH 30 330 8   HOH HOH L . 
I 5 HOH 31 331 147 HOH HOH L . 
I 5 HOH 32 332 29  HOH HOH L . 
I 5 HOH 33 333 51  HOH HOH L . 
I 5 HOH 34 334 139 HOH HOH L . 
I 5 HOH 35 335 154 HOH HOH L . 
I 5 HOH 36 336 158 HOH HOH L . 
I 5 HOH 37 337 12  HOH HOH L . 
I 5 HOH 38 338 110 HOH HOH L . 
I 5 HOH 39 339 226 HOH HOH L . 
I 5 HOH 40 340 20  HOH HOH L . 
I 5 HOH 41 341 91  HOH HOH L . 
I 5 HOH 42 342 1   HOH HOH L . 
I 5 HOH 43 343 168 HOH HOH L . 
I 5 HOH 44 344 115 HOH HOH L . 
I 5 HOH 45 345 80  HOH HOH L . 
I 5 HOH 46 346 26  HOH HOH L . 
I 5 HOH 47 347 179 HOH HOH L . 
I 5 HOH 48 348 126 HOH HOH L . 
I 5 HOH 49 349 75  HOH HOH L . 
I 5 HOH 50 350 172 HOH HOH L . 
I 5 HOH 51 351 62  HOH HOH L . 
I 5 HOH 52 352 191 HOH HOH L . 
I 5 HOH 53 353 142 HOH HOH L . 
I 5 HOH 54 354 31  HOH HOH L . 
I 5 HOH 55 355 206 HOH HOH L . 
I 5 HOH 56 356 74  HOH HOH L . 
I 5 HOH 57 357 203 HOH HOH L . 
I 5 HOH 58 358 107 HOH HOH L . 
I 5 HOH 59 359 45  HOH HOH L . 
I 5 HOH 60 360 184 HOH HOH L . 
I 5 HOH 61 361 223 HOH HOH L . 
I 5 HOH 62 362 201 HOH HOH L . 
I 5 HOH 63 363 106 HOH HOH L . 
I 5 HOH 64 364 2   HOH HOH L . 
I 5 HOH 65 365 187 HOH HOH L . 
I 5 HOH 66 366 151 HOH HOH L . 
I 5 HOH 67 367 86  HOH HOH L . 
I 5 HOH 68 368 202 HOH HOH L . 
J 5 HOH 1  301 46  HOH HOH A . 
J 5 HOH 2  302 217 HOH HOH A . 
J 5 HOH 3  303 48  HOH HOH A . 
J 5 HOH 4  304 11  HOH HOH A . 
J 5 HOH 5  305 87  HOH HOH A . 
J 5 HOH 6  306 214 HOH HOH A . 
J 5 HOH 7  307 114 HOH HOH A . 
J 5 HOH 8  308 112 HOH HOH A . 
J 5 HOH 9  309 70  HOH HOH A . 
J 5 HOH 10 310 169 HOH HOH A . 
J 5 HOH 11 311 95  HOH HOH A . 
J 5 HOH 12 312 164 HOH HOH A . 
J 5 HOH 13 313 72  HOH HOH A . 
J 5 HOH 14 314 108 HOH HOH A . 
J 5 HOH 15 315 58  HOH HOH A . 
J 5 HOH 16 316 156 HOH HOH A . 
J 5 HOH 17 317 180 HOH HOH A . 
J 5 HOH 18 318 81  HOH HOH A . 
J 5 HOH 19 319 128 HOH HOH A . 
J 5 HOH 20 320 89  HOH HOH A . 
J 5 HOH 21 321 132 HOH HOH A . 
J 5 HOH 22 322 15  HOH HOH A . 
J 5 HOH 23 323 165 HOH HOH A . 
J 5 HOH 24 324 198 HOH HOH A . 
J 5 HOH 25 325 189 HOH HOH A . 
J 5 HOH 26 326 25  HOH HOH A . 
J 5 HOH 27 327 42  HOH HOH A . 
J 5 HOH 28 328 34  HOH HOH A . 
J 5 HOH 29 329 83  HOH HOH A . 
J 5 HOH 30 330 9   HOH HOH A . 
J 5 HOH 31 331 41  HOH HOH A . 
J 5 HOH 32 332 157 HOH HOH A . 
J 5 HOH 33 333 166 HOH HOH A . 
J 5 HOH 34 334 146 HOH HOH A . 
J 5 HOH 35 335 171 HOH HOH A . 
J 5 HOH 36 336 232 HOH HOH A . 
J 5 HOH 37 337 174 HOH HOH A . 
J 5 HOH 38 338 150 HOH HOH A . 
J 5 HOH 39 339 160 HOH HOH A . 
J 5 HOH 40 340 117 HOH HOH A . 
J 5 HOH 41 341 218 HOH HOH A . 
J 5 HOH 42 342 213 HOH HOH A . 
J 5 HOH 43 343 19  HOH HOH A . 
J 5 HOH 44 344 173 HOH HOH A . 
J 5 HOH 45 345 182 HOH HOH A . 
J 5 HOH 46 346 153 HOH HOH A . 
K 5 HOH 1  301 121 HOH HOH B . 
K 5 HOH 2  302 236 HOH HOH B . 
K 5 HOH 3  303 136 HOH HOH B . 
K 5 HOH 4  304 220 HOH HOH B . 
K 5 HOH 5  305 228 HOH HOH B . 
K 5 HOH 6  306 122 HOH HOH B . 
K 5 HOH 7  307 118 HOH HOH B . 
K 5 HOH 8  308 94  HOH HOH B . 
K 5 HOH 9  309 44  HOH HOH B . 
K 5 HOH 10 310 99  HOH HOH B . 
K 5 HOH 11 311 138 HOH HOH B . 
K 5 HOH 12 312 193 HOH HOH B . 
K 5 HOH 13 313 135 HOH HOH B . 
K 5 HOH 14 314 188 HOH HOH B . 
K 5 HOH 15 315 84  HOH HOH B . 
K 5 HOH 16 316 167 HOH HOH B . 
K 5 HOH 17 317 109 HOH HOH B . 
K 5 HOH 18 318 209 HOH HOH B . 
K 5 HOH 19 319 196 HOH HOH B . 
K 5 HOH 20 320 52  HOH HOH B . 
K 5 HOH 21 321 219 HOH HOH B . 
K 5 HOH 22 322 103 HOH HOH B . 
K 5 HOH 23 323 194 HOH HOH B . 
K 5 HOH 24 324 90  HOH HOH B . 
K 5 HOH 25 325 170 HOH HOH B . 
K 5 HOH 26 326 82  HOH HOH B . 
K 5 HOH 27 327 77  HOH HOH B . 
K 5 HOH 28 328 21  HOH HOH B . 
K 5 HOH 29 329 175 HOH HOH B . 
K 5 HOH 30 330 155 HOH HOH B . 
K 5 HOH 31 331 55  HOH HOH B . 
K 5 HOH 32 332 130 HOH HOH B . 
K 5 HOH 33 333 40  HOH HOH B . 
K 5 HOH 34 334 68  HOH HOH B . 
K 5 HOH 35 335 39  HOH HOH B . 
K 5 HOH 36 336 120 HOH HOH B . 
K 5 HOH 37 337 137 HOH HOH B . 
K 5 HOH 38 338 24  HOH HOH B . 
K 5 HOH 39 339 162 HOH HOH B . 
K 5 HOH 40 340 100 HOH HOH B . 
K 5 HOH 41 341 215 HOH HOH B . 
K 5 HOH 42 342 210 HOH HOH B . 
K 5 HOH 43 343 101 HOH HOH B . 
L 5 HOH 1  101 163 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UJI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     92.498 
_cell.length_a_esd                 ? 
_cell.length_b                     139.615 
_cell.length_b_esd                 ? 
_cell.length_c                     73.616 
_cell.length_c_esd                 ? 
_cell.volume                       950684.994 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UJI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                18 
_symmetry.space_group_name_Hall            'P 2 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UJI 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.47 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          50.18 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M Lithium citrate, 20% PEG-3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-07-19 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          29.81 
_reflns.entry_id                                       8UJI 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.95 
_reflns.d_resolution_low                               39.34 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     68051 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     0.0 
_reflns.observed_criterion_sigma_I                     -3.0 
_reflns.percent_possible_obs                           97.5 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                10.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          17.6 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.35 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.149 
_reflns.pdbx_Rpim_I_all                                0.044 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.992 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.143 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                0.143 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.95 
_reflns_shell.d_res_low                                     1.98 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.2 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3151 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               7.8 
_reflns_shell.pdbx_chi_squared                              1.04 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               2.05 
_reflns_shell.pdbx_Rpim_I_all                               0.673 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.421 
_reflns_shell.pdbx_CC_star                                  0.77 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          91.3 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.93 
_reflns_shell.pdbx_Rsym_value                               1.93 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               37.81 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UJI 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.95 
_refine.ls_d_res_low                             39.34 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     68016 
_refine.ls_number_reflns_R_free                  3393 
_refine.ls_number_reflns_R_work                  64623 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.24 
_refine.ls_percent_reflns_R_free                 4.99 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2141 
_refine.ls_R_factor_R_free                       0.2599 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2117 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.5179 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2845 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.95 
_refine_hist.d_res_low                        39.34 
_refine_hist.number_atoms_solvent             219 
_refine_hist.number_atoms_total               6823 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        6600 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         4 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0056  ? 6765 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.9142  ? 9206 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0526  ? 1040 ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0057  ? 1174 ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.9092 ? 2397 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.95 1.98  . . 110 2274 82.95 . . . . 0.3499 . . . . . . . . . . . 0.3975 
'X-RAY DIFFRACTION' 1.98 2.01  . . 125 2675 96.92 . . . . 0.3200 . . . . . . . . . . . 0.4074 
'X-RAY DIFFRACTION' 2.01 2.04  . . 148 2644 97.08 . . . . 0.2865 . . . . . . . . . . . 0.3326 
'X-RAY DIFFRACTION' 2.04 2.07  . . 136 2672 98.18 . . . . 0.2674 . . . . . . . . . . . 0.3192 
'X-RAY DIFFRACTION' 2.07 2.11  . . 143 2709 98.96 . . . . 0.2571 . . . . . . . . . . . 0.2813 
'X-RAY DIFFRACTION' 2.11 2.15  . . 141 2724 98.83 . . . . 0.2585 . . . . . . . . . . . 0.3157 
'X-RAY DIFFRACTION' 2.15 2.19  . . 133 2713 99.13 . . . . 0.2630 . . . . . . . . . . . 0.3668 
'X-RAY DIFFRACTION' 2.19 2.23  . . 140 2723 98.93 . . . . 0.2528 . . . . . . . . . . . 0.3216 
'X-RAY DIFFRACTION' 2.23 2.28  . . 129 2687 98.50 . . . . 0.2500 . . . . . . . . . . . 0.2587 
'X-RAY DIFFRACTION' 2.28 2.34  . . 143 2703 98.89 . . . . 0.2595 . . . . . . . . . . . 0.3327 
'X-RAY DIFFRACTION' 2.34 2.40  . . 132 2735 99.07 . . . . 0.2429 . . . . . . . . . . . 0.2975 
'X-RAY DIFFRACTION' 2.40 2.46  . . 153 2672 97.35 . . . . 0.2415 . . . . . . . . . . . 0.3251 
'X-RAY DIFFRACTION' 2.46 2.53  . . 142 2535 92.02 . . . . 0.2422 . . . . . . . . . . . 0.3010 
'X-RAY DIFFRACTION' 2.53 2.61  . . 144 2707 98.79 . . . . 0.2348 . . . . . . . . . . . 0.2840 
'X-RAY DIFFRACTION' 2.61 2.71  . . 148 2723 99.24 . . . . 0.2311 . . . . . . . . . . . 0.2966 
'X-RAY DIFFRACTION' 2.71 2.82  . . 156 2738 99.04 . . . . 0.2291 . . . . . . . . . . . 0.2692 
'X-RAY DIFFRACTION' 2.82 2.94  . . 144 2734 98.83 . . . . 0.2304 . . . . . . . . . . . 0.2472 
'X-RAY DIFFRACTION' 2.94 3.10  . . 167 2730 98.74 . . . . 0.2274 . . . . . . . . . . . 0.2884 
'X-RAY DIFFRACTION' 3.10 3.29  . . 153 2701 98.14 . . . . 0.2107 . . . . . . . . . . . 0.2702 
'X-RAY DIFFRACTION' 3.29 3.55  . . 137 2711 97.30 . . . . 0.2079 . . . . . . . . . . . 0.2668 
'X-RAY DIFFRACTION' 3.55 3.90  . . 137 2628 93.41 . . . . 0.2008 . . . . . . . . . . . 0.2752 
'X-RAY DIFFRACTION' 3.90 4.47  . . 144 2801 99.53 . . . . 0.1689 . . . . . . . . . . . 0.2038 
'X-RAY DIFFRACTION' 4.47 5.63  . . 160 2831 99.20 . . . . 0.1550 . . . . . . . . . . . 0.1889 
'X-RAY DIFFRACTION' 5.63 39.34 . . 128 2853 94.94 . . . . 0.1670 . . . . . . . . . . . 0.1805 
# 
_struct.entry_id                     8UJI 
_struct.title                        'anti-Phosphohistidine Fab hSC44.ck with 3pTza peptide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UJI 
_struct_keywords.text            
'ANTI-PHOSPHOHISTIDINE ANTIBODY POST-TRANSLATIONAL MODIFICATION ANTIBODY HUMANIZATION, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 5 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8UJI 8UJI ? 1 ? 1 
2 PDB 8UJI 8UJI ? 2 ? 1 
3 PDB 8UJI 8UJI ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UJI H 1 ? 225 ? 8UJI 1 ? 221 ? 1 221 
2 2 8UJI L 1 ? 218 ? 8UJI 1 ? 212 ? 1 212 
3 1 8UJI A 1 ? 225 ? 8UJI 1 ? 221 ? 1 221 
4 2 8UJI B 1 ? 218 ? 8UJI 1 ? 212 ? 1 212 
5 3 8UJI C 1 ? 9   ? 8UJI 1 ? 9   ? 1 9   
6 3 8UJI D 1 ? 9   ? 8UJI 1 ? 9   ? 1 9   
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? trimeric 3 
2 author_defined_assembly ? trimeric 3 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,B,F,G,H,I,L 
2 1 C,D,E,J,K     
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? TYR A 32  ? SER H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2  AA2 SER A 61  ? LYS A 64  ? SER H 61  LYS H 64  5 ? 4 
HELX_P HELX_P3  AA3 ARG A 86  ? THR A 90  ? ARG H 83  THR H 87  5 ? 5 
HELX_P HELX_P4  AA4 SER A 160 ? ALA A 162 ? SER H 156 ALA H 158 5 ? 3 
HELX_P HELX_P5  AA5 SER A 191 ? LEU A 193 ? SER H 187 LEU H 189 5 ? 3 
HELX_P HELX_P6  AA6 LYS A 205 ? ASN A 208 ? LYS H 201 ASN H 204 5 ? 4 
HELX_P HELX_P7  AA7 VAL B 29  B LYS B 33  ? VAL L 27  LYS L 31  5 ? 5 
HELX_P HELX_P8  AA8 GLN B 81  ? PHE B 85  ? GLN L 79  PHE L 83  5 ? 5 
HELX_P HELX_P9  AA9 SER B 127 ? SER B 133 ? SER L 121 SER L 127 1 ? 7 
HELX_P HELX_P10 AB1 LYS B 189 ? LYS B 194 ? LYS L 183 LYS L 188 1 ? 6 
HELX_P HELX_P11 AB2 SER C 28  ? TYR C 32  ? SER A 28  TYR A 32  5 ? 5 
HELX_P HELX_P12 AB3 ALA C 60  ? SER C 65  ? ALA A 60  SER A 65  1 ? 6 
HELX_P HELX_P13 AB4 ARG C 86  ? THR C 90  ? ARG A 83  THR A 87  5 ? 5 
HELX_P HELX_P14 AB5 SER C 160 ? ALA C 162 ? SER A 156 ALA A 158 5 ? 3 
HELX_P HELX_P15 AB6 SER C 191 ? LEU C 193 ? SER A 187 LEU A 189 5 ? 3 
HELX_P HELX_P16 AB7 LYS C 205 ? ASN C 208 ? LYS A 201 ASN A 204 5 ? 4 
HELX_P HELX_P17 AB8 VAL D 29  B LYS D 33  ? VAL B 27  LYS B 31  5 ? 5 
HELX_P HELX_P18 AB9 GLN D 81  ? PHE D 85  ? GLN B 79  PHE B 83  5 ? 5 
HELX_P HELX_P19 AC1 SER D 127 ? LYS D 132 ? SER B 121 LYS B 126 1 ? 6 
HELX_P HELX_P20 AC2 LYS D 189 ? GLU D 193 ? LYS B 183 GLU B 187 1 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?    ? A CYS 22  SG ? ? ? 1_555 A CYS 95  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.023 ? ? 
disulf2  disulf ?    ? A CYS 144 SG A ? ? 1_555 A CYS 200 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.041 ? ? 
disulf3  disulf ?    ? A CYS 144 SG B ? ? 1_555 A CYS 200 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.070 ? ? 
disulf4  disulf ?    ? B CYS 23  SG ? ? ? 1_555 B CYS 90  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.052 ? ? 
disulf5  disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG A ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.017 ? ? 
disulf6  disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG B ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.057 ? ? 
disulf7  disulf ?    ? C CYS 22  SG ? ? ? 1_555 C CYS 95  SG ? ? A CYS 22  A CYS 92  1_555 ? ? ? ? ? ? ? 2.021 ? ? 
disulf8  disulf ?    ? C CYS 144 SG A ? ? 1_555 C CYS 200 SG ? ? A CYS 140 A CYS 196 1_555 ? ? ? ? ? ? ? 2.048 ? ? 
disulf9  disulf ?    ? C CYS 144 SG B ? ? 1_555 C CYS 200 SG ? ? A CYS 140 A CYS 196 1_555 ? ? ? ? ? ? ? 2.064 ? ? 
disulf10 disulf ?    ? D CYS 23  SG ? ? ? 1_555 D CYS 90  SG ? ? B CYS 23  B CYS 88  1_555 ? ? ? ? ? ? ? 2.055 ? ? 
disulf11 disulf ?    ? D CYS 140 SG ? ? ? 1_555 D CYS 200 SG A ? B CYS 134 B CYS 194 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf12 disulf ?    ? D CYS 140 SG ? ? ? 1_555 D CYS 200 SG B ? B CYS 134 B CYS 194 1_555 ? ? ? ? ? ? ? 2.059 ? ? 
covale1  covale both ? E GLY 4   C  ? ? ? 1_555 E UKD 5   N  ? ? C GLY 4   C UKD 5   1_555 ? ? ? ? ? ? ? 1.330 ? ? 
covale2  covale both ? E UKD 5   C  ? ? ? 1_555 E ALA 6   N  ? ? C UKD 5   C ALA 6   1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale3  covale both ? F GLY 4   C  ? ? ? 1_555 F UKD 5   N  ? ? D GLY 4   D UKD 5   1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale4  covale both ? F UKD 5   C  ? ? ? 1_555 F ALA 6   N  ? ? D UKD 5   D ALA 6   1_555 ? ? ? ? ? ? ? 1.328 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  UKD E 5   ? .   . .   . UKD C 5   ? 1_555 .   . .   . .     .  .  ? 1 UKD None 'Non-standard residue' 
2  UKD F 5   ? .   . .   . UKD D 5   ? 1_555 .   . .   . .     .  .  ? 1 UKD None 'Non-standard residue' 
3  CYS A 22  ? CYS A 95  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
4  CYS A 144 A CYS A 200 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
5  CYS A 144 B CYS A 200 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
6  CYS B 23  ? CYS B 90  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
7  CYS B 140 ? CYS B 200 A CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
8  CYS B 140 ? CYS B 200 B CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
9  CYS C 22  ? CYS C 95  ? CYS A 22  ? 1_555 CYS A 92  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
10 CYS C 144 A CYS C 200 ? CYS A 140 ? 1_555 CYS A 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
11 CYS C 144 B CYS C 200 ? CYS A 140 ? 1_555 CYS A 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
12 CYS D 23  ? CYS D 90  ? CYS B 23  ? 1_555 CYS B 88  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
13 CYS D 140 ? CYS D 200 A CYS B 134 ? 1_555 CYS B 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
14 CYS D 140 ? CYS D 200 B CYS B 134 ? 1_555 CYS B 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 150 A . ? PHE 146 H PRO 151 A ? PRO 147 H 1 -7.68 
2 GLU 152 A . ? GLU 148 H PRO 153 A ? PRO 149 H 1 -0.88 
3 SER 7   B . ? SER 7   L PRO 8   B ? PRO 8   L 1 -3.58 
4 TYR 146 B . ? TYR 140 L PRO 147 B ? PRO 141 L 1 1.19  
5 PHE 150 C . ? PHE 146 A PRO 151 C ? PRO 147 A 1 -5.89 
6 GLU 152 C . ? GLU 148 A PRO 153 C ? PRO 149 A 1 -4.02 
7 SER 7   D . ? SER 7   B PRO 8   D ? PRO 8   B 1 -7.90 
8 TYR 146 D . ? TYR 140 B PRO 147 D ? PRO 141 B 1 4.37  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 4 ? 
AB8 ? 3 ? 
AB9 ? 4 ? 
AC1 ? 6 ? 
AC2 ? 4 ? 
AC3 ? 4 ? 
AC4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? parallel      
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB7 3 4 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? parallel      
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC1 4 5 ? anti-parallel 
AC1 5 6 ? anti-parallel 
AC2 1 2 ? parallel      
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC3 3 4 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? SER A 7   ? GLN H 3   SER H 7   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 THR A 77  ? MET A 82  ? THR H 77  MET H 82  
AA1 4 SER A 67  ? ASN A 72  ? SER H 67  ASN H 72  
AA2 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA2 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA2 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA2 4 PHE A 34  ? GLN A 39  ? PHE H 34  GLN H 39  
AA2 5 GLU A 46  ? LEU A 51  ? GLU H 46  LEU H 51  
AA2 6 ALA A 57  ? TYR A 59  ? ALA H 57  TYR H 59  
AA3 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA3 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA3 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA3 4 ILE A 106 ? TRP A 107 ? ILE H 102 TRP H 103 
AA4 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA4 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA4 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA4 4 VAL A 167 ? THR A 169 ? VAL H 163 THR H 165 
AA5 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA5 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA5 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA5 4 VAL A 173 ? LEU A 174 ? VAL H 169 LEU H 170 
AA6 1 THR A 155 ? TRP A 158 ? THR H 151 TRP H 154 
AA6 2 ILE A 199 ? HIS A 204 ? ILE H 195 HIS H 200 
AA6 3 THR A 209 ? LYS A 214 ? THR H 205 LYS H 210 
AA7 1 MET B 4   ? SER B 7   ? MET L 4   SER L 7   
AA7 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA7 3 ASP B 72  ? ILE B 77  ? ASP L 70  ILE L 75  
AA7 4 PHE B 64  ? SER B 69  ? PHE L 62  SER L 67  
AA8 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA8 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA8 3 ALA B 86  ? TYR B 94  ? ALA L 84  TYR L 92  
AA8 4 VAL B 35  ? GLN B 40  ? VAL L 33  GLN L 38  
AA8 5 LYS B 47  ? TYR B 51  ? LYS L 45  TYR L 49  
AA8 6 SER B 55  ? LEU B 56  ? SER L 53  LEU L 54  
AA9 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA9 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA9 3 ALA B 86  ? TYR B 94  ? ALA L 84  TYR L 92  
AA9 4 TYR B 101 D PHE B 104 ? TYR L 95  PHE L 98  
AB1 1 SER B 120 ? PHE B 124 ? SER L 114 PHE L 118 
AB1 2 THR B 135 ? PHE B 145 ? THR L 129 PHE L 139 
AB1 3 TYR B 179 ? SER B 188 ? TYR L 173 SER L 182 
AB1 4 SER B 165 ? VAL B 169 ? SER L 159 VAL L 163 
AB2 1 ALA B 159 ? LEU B 160 ? ALA L 153 LEU L 154 
AB2 2 LYS B 151 ? VAL B 156 ? LYS L 145 VAL L 150 
AB2 3 VAL B 197 ? GLN B 204 ? VAL L 191 GLN L 198 
AB2 4 THR B 207 ? ASN B 214 ? THR L 201 ASN L 208 
AB3 1 GLN C 3   ? GLY C 8   ? GLN A 3   GLY A 8   
AB3 2 LEU C 18  ? SER C 25  ? LEU A 18  SER A 25  
AB3 3 THR C 77  ? MET C 82  ? THR A 77  MET A 82  
AB3 4 SER C 67  ? ASN C 72  ? SER A 67  ASN A 72  
AB4 1 GLY C 10  ? VAL C 12  ? GLY A 10  VAL A 12  
AB4 2 THR C 111 ? VAL C 115 ? THR A 107 VAL A 111 
AB4 3 ALA C 91  ? LYS C 97  ? ALA A 88  LYS A 94  
AB4 4 PHE C 34  ? GLN C 39  ? PHE A 34  GLN A 39  
AB4 5 GLU C 46  ? LEU C 51  ? GLU A 46  LEU A 51  
AB4 6 ALA C 57  ? TYR C 59  ? ALA A 57  TYR A 59  
AB5 1 GLY C 10  ? VAL C 12  ? GLY A 10  VAL A 12  
AB5 2 THR C 111 ? VAL C 115 ? THR A 107 VAL A 111 
AB5 3 ALA C 91  ? LYS C 97  ? ALA A 88  LYS A 94  
AB5 4 ILE C 106 ? TRP C 107 ? ILE A 102 TRP A 103 
AB6 1 SER C 124 ? LEU C 128 ? SER A 120 LEU A 124 
AB6 2 THR C 139 ? TYR C 149 ? THR A 135 TYR A 145 
AB6 3 TYR C 180 ? PRO C 189 ? TYR A 176 PRO A 185 
AB6 4 VAL C 167 ? THR C 169 ? VAL A 163 THR A 165 
AB7 1 SER C 124 ? LEU C 128 ? SER A 120 LEU A 124 
AB7 2 THR C 139 ? TYR C 149 ? THR A 135 TYR A 145 
AB7 3 TYR C 180 ? PRO C 189 ? TYR A 176 PRO A 185 
AB7 4 VAL C 173 ? LEU C 174 ? VAL A 169 LEU A 170 
AB8 1 THR C 155 ? TRP C 158 ? THR A 151 TRP A 154 
AB8 2 ILE C 199 ? HIS C 204 ? ILE A 195 HIS A 200 
AB8 3 THR C 209 ? LYS C 214 ? THR A 205 LYS A 210 
AB9 1 MET D 4   ? SER D 7   ? MET B 4   SER B 7   
AB9 2 VAL D 19  ? ALA D 25  ? VAL B 19  ALA B 25  
AB9 3 ASP D 72  ? ILE D 77  ? ASP B 70  ILE B 75  
AB9 4 PHE D 64  ? SER D 69  ? PHE B 62  SER B 67  
AC1 1 SER D 10  ? ALA D 13  ? SER B 10  ALA B 13  
AC1 2 THR D 108 ? ILE D 112 ? THR B 102 ILE B 106 
AC1 3 ALA D 86  ? TYR D 94  ? ALA B 84  TYR B 92  
AC1 4 VAL D 35  ? GLN D 40  ? VAL B 33  GLN B 38  
AC1 5 LYS D 47  ? TYR D 51  ? LYS B 45  TYR B 49  
AC1 6 SER D 55  ? LEU D 56  ? SER B 53  LEU B 54  
AC2 1 SER D 10  ? ALA D 13  ? SER B 10  ALA B 13  
AC2 2 THR D 108 ? ILE D 112 ? THR B 102 ILE B 106 
AC2 3 ALA D 86  ? TYR D 94  ? ALA B 84  TYR B 92  
AC2 4 TYR D 101 D PHE D 104 ? TYR B 95  PHE B 98  
AC3 1 SER D 120 ? PHE D 124 ? SER B 114 PHE B 118 
AC3 2 THR D 135 ? PHE D 145 ? THR B 129 PHE B 139 
AC3 3 TYR D 179 ? SER D 188 ? TYR B 173 SER B 182 
AC3 4 SER D 165 ? VAL D 169 ? SER B 159 VAL B 163 
AC4 1 ALA D 159 ? LEU D 160 ? ALA B 153 LEU B 154 
AC4 2 LYS D 151 ? VAL D 156 ? LYS B 145 VAL B 150 
AC4 3 VAL D 197 ? GLN D 204 ? VAL B 191 GLN B 198 
AC4 4 THR D 207 ? ASN D 214 ? THR B 201 ASN B 208 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N LEU A 20  ? N LEU H 20  O LEU A 80  ? O LEU H 80  
AA1 3 4 O THR A 79  ? O THR H 79  N THR A 70  ? N THR H 70  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA2 2 3 O VAL A 113 ? O VAL H 109 N ALA A 91  ? N ALA H 88  
AA2 3 4 O TYR A 94  ? O TYR H 91  N VAL A 37  ? N VAL H 37  
AA2 4 5 N TRP A 36  ? N TRP H 36  O ILE A 48  ? O ILE H 48  
AA2 5 6 N TYR A 50  ? N TYR H 50  O PHE A 58  ? O PHE H 58  
AA3 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA3 2 3 O VAL A 113 ? O VAL H 109 N ALA A 91  ? N ALA H 88  
AA3 3 4 N LYS A 97  ? N LYS H 94  O ILE A 106 ? O ILE H 102 
AA4 1 2 N PHE A 126 ? N PHE H 122 O LEU A 145 ? O LEU H 141 
AA4 2 3 N VAL A 146 ? N VAL H 142 O LEU A 182 ? O LEU H 178 
AA4 3 4 O VAL A 185 ? O VAL H 181 N HIS A 168 ? N HIS H 164 
AA5 1 2 N PHE A 126 ? N PHE H 122 O LEU A 145 ? O LEU H 141 
AA5 2 3 N VAL A 146 ? N VAL H 142 O LEU A 182 ? O LEU H 178 
AA5 3 4 O SER A 181 ? O SER H 177 N VAL A 173 ? N VAL H 169 
AA6 1 2 N SER A 157 ? N SER H 153 O ASN A 201 ? O ASN H 197 
AA6 2 3 N VAL A 202 ? N VAL H 198 O VAL A 211 ? O VAL H 207 
AA7 1 2 N THR B 5   ? N THR L 5   O ARG B 24  ? O ARG L 24  
AA7 2 3 N CYS B 23  ? N CYS L 23  O PHE B 73  ? O PHE L 71  
AA7 3 4 O THR B 74  ? O THR L 72  N SER B 67  ? N SER L 65  
AA8 1 2 N LEU B 11  ? N LEU L 11  O GLU B 111 ? O GLU L 105 
AA8 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA8 3 4 O TYR B 89  ? O TYR L 87  N TYR B 38  ? N TYR L 36  
AA8 4 5 N TRP B 37  ? N TRP L 35  O LEU B 49  ? O LEU L 47  
AA8 5 6 N TYR B 51  ? N TYR L 49  O SER B 55  ? O SER L 53  
AA9 1 2 N LEU B 11  ? N LEU L 11  O GLU B 111 ? O GLU L 105 
AA9 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA9 3 4 N TYR B 94  ? N TYR L 92  O TYR B 101 D O TYR L 95  
AB1 1 2 N PHE B 122 ? N PHE L 116 O LEU B 141 ? O LEU L 135 
AB1 2 3 N VAL B 138 ? N VAL L 132 O LEU B 185 ? O LEU L 179 
AB1 3 4 O SER B 182 ? O SER L 176 N SER B 168 ? N SER L 162 
AB2 1 2 O ALA B 159 ? O ALA L 153 N VAL B 156 ? N VAL L 150 
AB2 2 3 N SER B 153 ? N SER L 147 O GLU B 201 ? O GLU L 195 
AB2 3 4 N VAL B 202 ? N VAL L 196 O VAL B 209 ? O VAL L 203 
AB3 1 2 N GLN C 3   ? N GLN A 3   O SER C 25  ? O SER A 25  
AB3 2 3 N LEU C 20  ? N LEU A 20  O LEU C 80  ? O LEU A 80  
AB3 3 4 O THR C 79  ? O THR A 79  N THR C 70  ? N THR A 70  
AB4 1 2 N VAL C 12  ? N VAL A 12  O THR C 114 ? O THR A 110 
AB4 2 3 O THR C 111 ? O THR A 107 N TYR C 93  ? N TYR A 90  
AB4 3 4 O ALA C 96  ? O ALA A 93  N SER C 35  ? N SER A 35  
AB4 4 5 N PHE C 34  ? N PHE A 34  O LEU C 51  ? O LEU A 51  
AB4 5 6 N TYR C 50  ? N TYR A 50  O PHE C 58  ? O PHE A 58  
AB5 1 2 N VAL C 12  ? N VAL A 12  O THR C 114 ? O THR A 110 
AB5 2 3 O THR C 111 ? O THR A 107 N TYR C 93  ? N TYR A 90  
AB5 3 4 N LYS C 97  ? N LYS A 94  O ILE C 106 ? O ILE A 102 
AB6 1 2 N LEU C 128 ? N LEU A 124 O GLY C 143 ? O GLY A 139 
AB6 2 3 N VAL C 146 ? N VAL A 142 O LEU C 182 ? O LEU A 178 
AB6 3 4 O VAL C 185 ? O VAL A 181 N HIS C 168 ? N HIS A 164 
AB7 1 2 N LEU C 128 ? N LEU A 124 O GLY C 143 ? O GLY A 139 
AB7 2 3 N VAL C 146 ? N VAL A 142 O LEU C 182 ? O LEU A 178 
AB7 3 4 O SER C 181 ? O SER A 177 N VAL C 173 ? N VAL A 169 
AB8 1 2 N SER C 157 ? N SER A 153 O ASN C 201 ? O ASN A 197 
AB8 2 3 N VAL C 202 ? N VAL A 198 O VAL C 211 ? O VAL A 207 
AB9 1 2 N THR D 5   ? N THR B 5   O ARG D 24  ? O ARG B 24  
AB9 2 3 N ILE D 21  ? N ILE B 21  O LEU D 75  ? O LEU B 73  
AB9 3 4 O THR D 76  ? O THR B 74  N SER D 65  ? N SER B 63  
AC1 1 2 N LEU D 11  ? N LEU B 11  O GLU D 111 ? O GLU B 105 
AC1 2 3 O VAL D 110 ? O VAL B 104 N ALA D 86  ? N ALA B 84  
AC1 3 4 O TYR D 89  ? O TYR B 87  N TYR D 38  ? N TYR B 36  
AC1 4 5 N GLN D 39  ? N GLN B 37  O LYS D 47  ? O LYS B 45  
AC1 5 6 N TYR D 51  ? N TYR B 49  O SER D 55  ? O SER B 53  
AC2 1 2 N LEU D 11  ? N LEU B 11  O GLU D 111 ? O GLU B 105 
AC2 2 3 O VAL D 110 ? O VAL B 104 N ALA D 86  ? N ALA B 84  
AC2 3 4 N TYR D 94  ? N TYR B 92  O TYR D 101 D O TYR B 95  
AC3 1 2 N PHE D 124 ? N PHE B 118 O VAL D 139 ? O VAL B 133 
AC3 2 3 N VAL D 138 ? N VAL B 132 O LEU D 185 ? O LEU B 179 
AC3 3 4 O SER D 182 ? O SER B 176 N SER D 168 ? N SER B 162 
AC4 1 2 O ALA D 159 ? O ALA B 153 N VAL D 156 ? N VAL B 150 
AC4 2 3 N SER D 153 ? N SER B 147 O GLU D 201 ? O GLU B 195 
AC4 3 4 N VAL D 202 ? N VAL B 196 O VAL D 209 ? O VAL B 203 
# 
_pdbx_entry_details.entry_id                   8UJI 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA H CYS 140 ? B CB H CYS 140 ? B SG H CYS 140 ? B 123.00 114.20 8.80 1.10 N 
2 1 CA A CYS 140 ? B CB A CYS 140 ? B SG A CYS 140 ? B 123.22 114.20 9.02 1.10 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ILE H 48  ? ? -91.96  -61.60  
2  1 ARG L 29  ? ? 58.70   16.32   
3  1 ILE L 51  ? ? 70.55   -43.11  
4  1 SER L 94  ? ? -122.21 -164.24 
5  1 LEU A 4   ? ? -162.18 94.86   
6  1 SER A 130 ? ? 62.51   -3.20   
7  1 THR A 131 ? ? 39.02   -101.34 
8  1 SER A 132 ? ? 3.12    105.22  
9  1 ARG B 29  ? ? 56.61   19.10   
10 1 LYS B 31  ? ? -146.04 -26.98  
11 1 ILE B 51  ? ? 73.10   -48.84  
12 1 PHE B 83  ? ? -54.25  101.81  
13 1 SER B 94  ? ? -117.12 -167.15 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x+1/2,y+1/2,-z 
4 -x,-y,z         
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H GLU 1   ? A GLU 1   
2  1 Y 1 H SER 215 ? A SER 219 
3  1 Y 1 H CYS 216 ? A CYS 220 
4  1 Y 1 H ASP 217 ? A ASP 221 
5  1 Y 1 H LYS 218 ? A LYS 222 
6  1 Y 1 H THR 219 ? A THR 223 
7  1 Y 1 H HIS 220 ? A HIS 224 
8  1 Y 1 H THR 221 ? A THR 225 
9  1 Y 1 A GLU 1   ? C GLU 1   
10 1 Y 1 A SER 215 ? C SER 219 
11 1 Y 1 A CYS 216 ? C CYS 220 
12 1 Y 1 A ASP 217 ? C ASP 221 
13 1 Y 1 A LYS 218 ? C LYS 222 
14 1 Y 1 A THR 219 ? C THR 223 
15 1 Y 1 A HIS 220 ? C HIS 224 
16 1 Y 1 A THR 221 ? C THR 225 
17 1 Y 1 C ALA 1   ? E ALA 1   
18 1 Y 1 C GLY 2   ? E GLY 2   
19 1 Y 1 C ALA 3   ? E ALA 3   
20 1 Y 1 C GLY 9   ? E GLY 9   
21 1 Y 1 D ALA 1   ? F ALA 1   
22 1 Y 1 D GLY 2   ? F GLY 2   
23 1 Y 1 D ALA 8   ? F ALA 8   
24 1 Y 1 D GLY 9   ? F GLY 9   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
HIS N    N N N 147 
HIS CA   C N S 148 
HIS C    C N N 149 
HIS O    O N N 150 
HIS CB   C N N 151 
HIS CG   C Y N 152 
HIS ND1  N Y N 153 
HIS CD2  C Y N 154 
HIS CE1  C Y N 155 
HIS NE2  N Y N 156 
HIS OXT  O N N 157 
HIS H    H N N 158 
HIS H2   H N N 159 
HIS HA   H N N 160 
HIS HB2  H N N 161 
HIS HB3  H N N 162 
HIS HD1  H N N 163 
HIS HD2  H N N 164 
HIS HE1  H N N 165 
HIS HE2  H N N 166 
HIS HXT  H N N 167 
HOH O    O N N 168 
HOH H1   H N N 169 
HOH H2   H N N 170 
ILE N    N N N 171 
ILE CA   C N S 172 
ILE C    C N N 173 
ILE O    O N N 174 
ILE CB   C N S 175 
ILE CG1  C N N 176 
ILE CG2  C N N 177 
ILE CD1  C N N 178 
ILE OXT  O N N 179 
ILE H    H N N 180 
ILE H2   H N N 181 
ILE HA   H N N 182 
ILE HB   H N N 183 
ILE HG12 H N N 184 
ILE HG13 H N N 185 
ILE HG21 H N N 186 
ILE HG22 H N N 187 
ILE HG23 H N N 188 
ILE HD11 H N N 189 
ILE HD12 H N N 190 
ILE HD13 H N N 191 
ILE HXT  H N N 192 
LEU N    N N N 193 
LEU CA   C N S 194 
LEU C    C N N 195 
LEU O    O N N 196 
LEU CB   C N N 197 
LEU CG   C N N 198 
LEU CD1  C N N 199 
LEU CD2  C N N 200 
LEU OXT  O N N 201 
LEU H    H N N 202 
LEU H2   H N N 203 
LEU HA   H N N 204 
LEU HB2  H N N 205 
LEU HB3  H N N 206 
LEU HG   H N N 207 
LEU HD11 H N N 208 
LEU HD12 H N N 209 
LEU HD13 H N N 210 
LEU HD21 H N N 211 
LEU HD22 H N N 212 
LEU HD23 H N N 213 
LEU HXT  H N N 214 
LYS N    N N N 215 
LYS CA   C N S 216 
LYS C    C N N 217 
LYS O    O N N 218 
LYS CB   C N N 219 
LYS CG   C N N 220 
LYS CD   C N N 221 
LYS CE   C N N 222 
LYS NZ   N N N 223 
LYS OXT  O N N 224 
LYS H    H N N 225 
LYS H2   H N N 226 
LYS HA   H N N 227 
LYS HB2  H N N 228 
LYS HB3  H N N 229 
LYS HG2  H N N 230 
LYS HG3  H N N 231 
LYS HD2  H N N 232 
LYS HD3  H N N 233 
LYS HE2  H N N 234 
LYS HE3  H N N 235 
LYS HZ1  H N N 236 
LYS HZ2  H N N 237 
LYS HZ3  H N N 238 
LYS HXT  H N N 239 
MET N    N N N 240 
MET CA   C N S 241 
MET C    C N N 242 
MET O    O N N 243 
MET CB   C N N 244 
MET CG   C N N 245 
MET SD   S N N 246 
MET CE   C N N 247 
MET OXT  O N N 248 
MET H    H N N 249 
MET H2   H N N 250 
MET HA   H N N 251 
MET HB2  H N N 252 
MET HB3  H N N 253 
MET HG2  H N N 254 
MET HG3  H N N 255 
MET HE1  H N N 256 
MET HE2  H N N 257 
MET HE3  H N N 258 
MET HXT  H N N 259 
PHE N    N N N 260 
PHE CA   C N S 261 
PHE C    C N N 262 
PHE O    O N N 263 
PHE CB   C N N 264 
PHE CG   C Y N 265 
PHE CD1  C Y N 266 
PHE CD2  C Y N 267 
PHE CE1  C Y N 268 
PHE CE2  C Y N 269 
PHE CZ   C Y N 270 
PHE OXT  O N N 271 
PHE H    H N N 272 
PHE H2   H N N 273 
PHE HA   H N N 274 
PHE HB2  H N N 275 
PHE HB3  H N N 276 
PHE HD1  H N N 277 
PHE HD2  H N N 278 
PHE HE1  H N N 279 
PHE HE2  H N N 280 
PHE HZ   H N N 281 
PHE HXT  H N N 282 
PRO N    N N N 283 
PRO CA   C N S 284 
PRO C    C N N 285 
PRO O    O N N 286 
PRO CB   C N N 287 
PRO CG   C N N 288 
PRO CD   C N N 289 
PRO OXT  O N N 290 
PRO H    H N N 291 
PRO HA   H N N 292 
PRO HB2  H N N 293 
PRO HB3  H N N 294 
PRO HG2  H N N 295 
PRO HG3  H N N 296 
PRO HD2  H N N 297 
PRO HD3  H N N 298 
PRO HXT  H N N 299 
SER N    N N N 300 
SER CA   C N S 301 
SER C    C N N 302 
SER O    O N N 303 
SER CB   C N N 304 
SER OG   O N N 305 
SER OXT  O N N 306 
SER H    H N N 307 
SER H2   H N N 308 
SER HA   H N N 309 
SER HB2  H N N 310 
SER HB3  H N N 311 
SER HG   H N N 312 
SER HXT  H N N 313 
THR N    N N N 314 
THR CA   C N S 315 
THR C    C N N 316 
THR O    O N N 317 
THR CB   C N R 318 
THR OG1  O N N 319 
THR CG2  C N N 320 
THR OXT  O N N 321 
THR H    H N N 322 
THR H2   H N N 323 
THR HA   H N N 324 
THR HB   H N N 325 
THR HG1  H N N 326 
THR HG21 H N N 327 
THR HG22 H N N 328 
THR HG23 H N N 329 
THR HXT  H N N 330 
TRP N    N N N 331 
TRP CA   C N S 332 
TRP C    C N N 333 
TRP O    O N N 334 
TRP CB   C N N 335 
TRP CG   C Y N 336 
TRP CD1  C Y N 337 
TRP CD2  C Y N 338 
TRP NE1  N Y N 339 
TRP CE2  C Y N 340 
TRP CE3  C Y N 341 
TRP CZ2  C Y N 342 
TRP CZ3  C Y N 343 
TRP CH2  C Y N 344 
TRP OXT  O N N 345 
TRP H    H N N 346 
TRP H2   H N N 347 
TRP HA   H N N 348 
TRP HB2  H N N 349 
TRP HB3  H N N 350 
TRP HD1  H N N 351 
TRP HE1  H N N 352 
TRP HE3  H N N 353 
TRP HZ2  H N N 354 
TRP HZ3  H N N 355 
TRP HH2  H N N 356 
TRP HXT  H N N 357 
TYR N    N N N 358 
TYR CA   C N S 359 
TYR C    C N N 360 
TYR O    O N N 361 
TYR CB   C N N 362 
TYR CG   C Y N 363 
TYR CD1  C Y N 364 
TYR CD2  C Y N 365 
TYR CE1  C Y N 366 
TYR CE2  C Y N 367 
TYR CZ   C Y N 368 
TYR OH   O N N 369 
TYR OXT  O N N 370 
TYR H    H N N 371 
TYR H2   H N N 372 
TYR HA   H N N 373 
TYR HB2  H N N 374 
TYR HB3  H N N 375 
TYR HD1  H N N 376 
TYR HD2  H N N 377 
TYR HE1  H N N 378 
TYR HE2  H N N 379 
TYR HH   H N N 380 
TYR HXT  H N N 381 
UKD O3   O N N 382 
UKD O4   O N N 383 
UKD P    P N N 384 
UKD O1   O N N 385 
UKD CE2  C Y N 386 
UKD NE1  N Y N 387 
UKD ND1  N Y N 388 
UKD CD2  C Y N 389 
UKD NG   N Y N 390 
UKD CB   C N N 391 
UKD CA   C N S 392 
UKD N    N N N 393 
UKD C    C N N 394 
UKD O    O N N 395 
UKD H1   H N N 396 
UKD H11  H N N 397 
UKD H3   H N N 398 
UKD H4   H N N 399 
UKD H5   H N N 400 
UKD HA   H N N 401 
UKD H    H N N 402 
UKD H2   H N N 403 
UKD OXT  O N N 404 
UKD HXT  H N N 405 
VAL N    N N N 406 
VAL CA   C N S 407 
VAL C    C N N 408 
VAL O    O N N 409 
VAL CB   C N N 410 
VAL CG1  C N N 411 
VAL CG2  C N N 412 
VAL OXT  O N N 413 
VAL H    H N N 414 
VAL H2   H N N 415 
VAL HA   H N N 416 
VAL HB   H N N 417 
VAL HG11 H N N 418 
VAL HG12 H N N 419 
VAL HG13 H N N 420 
VAL HG21 H N N 421 
VAL HG22 H N N 422 
VAL HG23 H N N 423 
VAL HXT  H N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TRP N   CA   sing N N 315 
TRP N   H    sing N N 316 
TRP N   H2   sing N N 317 
TRP CA  C    sing N N 318 
TRP CA  CB   sing N N 319 
TRP CA  HA   sing N N 320 
TRP C   O    doub N N 321 
TRP C   OXT  sing N N 322 
TRP CB  CG   sing N N 323 
TRP CB  HB2  sing N N 324 
TRP CB  HB3  sing N N 325 
TRP CG  CD1  doub Y N 326 
TRP CG  CD2  sing Y N 327 
TRP CD1 NE1  sing Y N 328 
TRP CD1 HD1  sing N N 329 
TRP CD2 CE2  doub Y N 330 
TRP CD2 CE3  sing Y N 331 
TRP NE1 CE2  sing Y N 332 
TRP NE1 HE1  sing N N 333 
TRP CE2 CZ2  sing Y N 334 
TRP CE3 CZ3  doub Y N 335 
TRP CE3 HE3  sing N N 336 
TRP CZ2 CH2  doub Y N 337 
TRP CZ2 HZ2  sing N N 338 
TRP CZ3 CH2  sing Y N 339 
TRP CZ3 HZ3  sing N N 340 
TRP CH2 HH2  sing N N 341 
TRP OXT HXT  sing N N 342 
TYR N   CA   sing N N 343 
TYR N   H    sing N N 344 
TYR N   H2   sing N N 345 
TYR CA  C    sing N N 346 
TYR CA  CB   sing N N 347 
TYR CA  HA   sing N N 348 
TYR C   O    doub N N 349 
TYR C   OXT  sing N N 350 
TYR CB  CG   sing N N 351 
TYR CB  HB2  sing N N 352 
TYR CB  HB3  sing N N 353 
TYR CG  CD1  doub Y N 354 
TYR CG  CD2  sing Y N 355 
TYR CD1 CE1  sing Y N 356 
TYR CD1 HD1  sing N N 357 
TYR CD2 CE2  doub Y N 358 
TYR CD2 HD2  sing N N 359 
TYR CE1 CZ   doub Y N 360 
TYR CE1 HE1  sing N N 361 
TYR CE2 CZ   sing Y N 362 
TYR CE2 HE2  sing N N 363 
TYR CZ  OH   sing N N 364 
TYR OH  HH   sing N N 365 
TYR OXT HXT  sing N N 366 
UKD O   C    doub N N 367 
UKD C   CA   sing N N 368 
UKD N   CA   sing N N 369 
UKD CA  CB   sing N N 370 
UKD CB  NG   sing N N 371 
UKD NG  ND1  sing Y N 372 
UKD NG  CD2  sing Y N 373 
UKD ND1 NE1  doub Y N 374 
UKD CD2 CE2  doub Y N 375 
UKD NE1 CE2  sing Y N 376 
UKD CE2 P    sing N N 377 
UKD P   O4   doub N N 378 
UKD P   O3   sing N N 379 
UKD P   O1   sing N N 380 
UKD O3  H1   sing N N 381 
UKD O1  H11  sing N N 382 
UKD CD2 H3   sing N N 383 
UKD CB  H4   sing N N 384 
UKD CB  H5   sing N N 385 
UKD CA  HA   sing N N 386 
UKD N   H    sing N N 387 
UKD N   H2   sing N N 388 
UKD C   OXT  sing N N 389 
UKD OXT HXT  sing N N 390 
VAL N   CA   sing N N 391 
VAL N   H    sing N N 392 
VAL N   H2   sing N N 393 
VAL CA  C    sing N N 394 
VAL CA  CB   sing N N 395 
VAL CA  HA   sing N N 396 
VAL C   O    doub N N 397 
VAL C   OXT  sing N N 398 
VAL CB  CG1  sing N N 399 
VAL CB  CG2  sing N N 400 
VAL CB  HB   sing N N 401 
VAL CG1 HG11 sing N N 402 
VAL CG1 HG12 sing N N 403 
VAL CG1 HG13 sing N N 404 
VAL CG2 HG21 sing N N 405 
VAL CG2 HG22 sing N N 406 
VAL CG2 HG23 sing N N 407 
VAL OXT HXT  sing N N 408 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           CA242443 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6X1V 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 2' 
_space_group.name_Hall        'P 2 2ab' 
_space_group.IT_number        18 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8UJI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010811 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.007163 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.013584 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . VAL A 1 2   ? 14.74129  36.55353 10.53744  1.000 55.61258  ? 2   VAL H N   1 
ATOM   2    C CA  . VAL A 1 2   ? 15.58897  35.40806 10.23132  1.000 62.75097  ? 2   VAL H CA  1 
ATOM   3    C C   . VAL A 1 2   ? 14.85525  34.10704 10.55910  1.000 66.44540  ? 2   VAL H C   1 
ATOM   4    O O   . VAL A 1 2   ? 14.49041  33.86429 11.71017  1.000 67.77110  ? 2   VAL H O   1 
ATOM   5    C CB  . VAL A 1 2   ? 16.92614  35.48664 10.98989  1.000 58.61483  ? 2   VAL H CB  1 
ATOM   6    C CG1 . VAL A 1 2   ? 17.85965  34.39356 10.51855  1.000 55.72618  ? 2   VAL H CG1 1 
ATOM   7    C CG2 . VAL A 1 2   ? 17.56742  36.85474 10.80702  1.000 59.39206  ? 2   VAL H CG2 1 
ATOM   8    N N   . GLN A 1 3   ? 14.64353  33.27166 9.54237   1.000 67.82146  ? 3   GLN H N   1 
ATOM   9    C CA  . GLN A 1 3   ? 13.90415  32.02513 9.68480   1.000 66.38752  ? 3   GLN H CA  1 
ATOM   10   C C   . GLN A 1 3   ? 14.63544  30.89137 8.97886   1.000 62.96822  ? 3   GLN H C   1 
ATOM   11   O O   . GLN A 1 3   ? 15.53172  31.10307 8.15744   1.000 57.89087  ? 3   GLN H O   1 
ATOM   12   C CB  . GLN A 1 3   ? 12.47737  32.14346 9.13064   1.000 65.45954  ? 3   GLN H CB  1 
ATOM   13   C CG  . GLN A 1 3   ? 11.49678  32.84050 10.06062  1.000 69.76685  ? 3   GLN H CG  1 
ATOM   14   C CD  . GLN A 1 3   ? 10.06584  32.78759 9.54631   1.000 76.64049  ? 3   GLN H CD  1 
ATOM   15   O OE1 . GLN A 1 3   ? 9.74569   32.00977 8.64547   1.000 71.36147  ? 3   GLN H OE1 1 
ATOM   16   N NE2 . GLN A 1 3   ? 9.19806   33.62018 10.11689  1.000 77.04160  ? 3   GLN H NE2 1 
ATOM   17   N N   . LEU A 1 4   ? 14.22325  29.66693 9.31179   1.000 58.01712  ? 4   LEU H N   1 
ATOM   18   C CA  . LEU A 1 4   ? 14.77439  28.44164 8.75819   1.000 58.00729  ? 4   LEU H CA  1 
ATOM   19   C C   . LEU A 1 4   ? 13.61825  27.44632 8.65136   1.000 59.63263  ? 4   LEU H C   1 
ATOM   20   O O   . LEU A 1 4   ? 13.50351  26.50268 9.41961   1.000 61.23273  ? 4   LEU H O   1 
ATOM   21   C CB  . LEU A 1 4   ? 15.90715  27.89324 9.62829   1.000 50.92701  ? 4   LEU H CB  1 
ATOM   22   C CG  . LEU A 1 4   ? 17.03680  27.10058 8.98600   1.000 58.34464  ? 4   LEU H CG  1 
ATOM   23   C CD1 . LEU A 1 4   ? 17.75309  27.96133 7.96309   1.000 59.23454  ? 4   LEU H CD1 1 
ATOM   24   C CD2 . LEU A 1 4   ? 18.01314  26.62275 10.05382  1.000 47.79750  ? 4   LEU H CD2 1 
ATOM   25   N N   . VAL A 1 5   ? 12.72874  27.66444 7.68451   1.000 66.90255  ? 5   VAL H N   1 
ATOM   26   C CA  . VAL A 1 5   ? 11.54829  26.81623 7.54616   1.000 66.11043  ? 5   VAL H CA  1 
ATOM   27   C C   . VAL A 1 5   ? 11.93568  25.50017 6.88123   1.000 65.79483  ? 5   VAL H C   1 
ATOM   28   O O   . VAL A 1 5   ? 12.70848  25.47032 5.91210   1.000 63.06985  ? 5   VAL H O   1 
ATOM   29   C CB  . VAL A 1 5   ? 10.43939  27.54379 6.76471   1.000 66.95921  ? 5   VAL H CB  1 
ATOM   30   C CG1 . VAL A 1 5   ? 9.21349   26.65327 6.62495   1.000 67.40568  ? 5   VAL H CG1 1 
ATOM   31   C CG2 . VAL A 1 5   ? 10.06665  28.84791 7.46229   1.000 71.28754  ? 5   VAL H CG2 1 
ATOM   32   N N   . GLU A 1 6   ? 11.39340  24.40350 7.41074   1.000 71.54287  ? 6   GLU H N   1 
ATOM   33   C CA  . GLU A 1 6   ? 11.72504  23.04745 6.99931   1.000 62.92956  ? 6   GLU H CA  1 
ATOM   34   C C   . GLU A 1 6   ? 10.68018  22.49088 6.04104   1.000 61.93553  ? 6   GLU H C   1 
ATOM   35   O O   . GLU A 1 6   ? 9.52374   22.92339 6.01753   1.000 66.30886  ? 6   GLU H O   1 
ATOM   36   C CB  . GLU A 1 6   ? 11.82935  22.12300 8.21171   1.000 59.00842  ? 6   GLU H CB  1 
ATOM   37   C CG  . GLU A 1 6   ? 12.58751  22.69579 9.38643   1.000 58.61301  ? 6   GLU H CG  1 
ATOM   38   C CD  . GLU A 1 6   ? 13.09301  21.60686 10.29861  1.000 49.87108  ? 6   GLU H CD  1 
ATOM   39   O OE1 . GLU A 1 6   ? 12.55946  20.47725 10.20921  1.000 55.83776  ? 6   GLU H OE1 1 
ATOM   40   O OE2 . GLU A 1 6   ? 14.03488  21.86698 11.08237  1.000 51.79636  ? 6   GLU H OE2 1 
ATOM   41   N N   . SER A 1 7   ? 11.09836  21.49105 5.26880   1.000 54.52562  ? 7   SER H N   1 
ATOM   42   C CA  . SER A 1 7   ? 10.22066  20.89031 4.27607   1.000 57.63083  ? 7   SER H CA  1 
ATOM   43   C C   . SER A 1 7   ? 10.69192  19.47749 3.97826   1.000 51.06403  ? 7   SER H C   1 
ATOM   44   O O   . SER A 1 7   ? 11.89468  19.19688 3.98024   1.000 51.80857  ? 7   SER H O   1 
ATOM   45   C CB  . SER A 1 7   ? 10.20628  21.70801 2.98269   1.000 58.37076  ? 7   SER H CB  1 
ATOM   46   O OG  . SER A 1 7   ? 11.49454  21.68222 2.38959   1.000 52.45477  ? 7   SER H OG  1 
ATOM   47   N N   . GLY A 1 8   ? 9.73188   18.59953 3.70229   1.000 48.66333  ? 8   GLY H N   1 
ATOM   48   C CA  . GLY A 1 8   ? 10.02639  17.26712 3.22464   1.000 40.94237  ? 8   GLY H CA  1 
ATOM   49   C C   . GLY A 1 8   ? 9.67399   16.12866 4.15928   1.000 54.68867  ? 8   GLY H C   1 
ATOM   50   O O   . GLY A 1 8   ? 10.10211  14.99497 3.90501   1.000 59.59836  ? 8   GLY H O   1 
ATOM   51   N N   . GLY A 1 9   ? 8.91086   16.38084 5.22387   1.000 43.50205  ? 9   GLY H N   1 
ATOM   52   C CA  . GLY A 1 9   ? 8.60902   15.36516 6.20871   1.000 44.49560  ? 9   GLY H CA  1 
ATOM   53   C C   . GLY A 1 9   ? 7.38485   14.54666 5.85007   1.000 47.30679  ? 9   GLY H C   1 
ATOM   54   O O   . GLY A 1 9   ? 6.87446   14.58248 4.72887   1.000 44.21381  ? 9   GLY H O   1 
ATOM   55   N N   . GLY A 1 10  ? 6.92518   13.76980 6.83231   1.000 32.92149  ? 10  GLY H N   1 
ATOM   56   C CA  . GLY A 1 10  ? 5.63979   13.11040 6.75857   1.000 36.22147  ? 10  GLY H CA  1 
ATOM   57   C C   . GLY A 1 10  ? 5.77799   11.60068 6.82255   1.000 29.84877  ? 10  GLY H C   1 
ATOM   58   O O   . GLY A 1 10  ? 6.74701   11.07078 7.38240   1.000 27.34278  ? 10  GLY H O   1 
ATOM   59   N N   . LEU A 1 11  ? 4.80574   10.92057 6.22904   1.000 28.46950  ? 11  LEU H N   1 
ATOM   60   C CA  . LEU A 1 11  ? 4.72340   9.46602  6.26452   1.000 22.52418  ? 11  LEU H CA  1 
ATOM   61   C C   . LEU A 1 11  ? 5.58419   8.86940  5.15221   1.000 23.67743  ? 11  LEU H C   1 
ATOM   62   O O   . LEU A 1 11  ? 5.41516   9.22410  3.98200   1.000 25.42153  ? 11  LEU H O   1 
ATOM   63   C CB  . LEU A 1 11  ? 3.25951   9.05654  6.12513   1.000 26.10151  ? 11  LEU H CB  1 
ATOM   64   C CG  . LEU A 1 11  ? 2.85744   7.58410  6.13377   1.000 29.33636  ? 11  LEU H CG  1 
ATOM   65   C CD1 . LEU A 1 11  ? 3.15403   6.95307  7.48415   1.000 23.12774  ? 11  LEU H CD1 1 
ATOM   66   C CD2 . LEU A 1 11  ? 1.38456   7.47092  5.81546   1.000 25.61845  ? 11  LEU H CD2 1 
ATOM   67   N N   . VAL A 1 12  ? 6.50525   7.96509  5.51907   1.000 22.73086  ? 12  VAL H N   1 
ATOM   68   C CA  . VAL A 1 12  ? 7.45493   7.33248  4.60702   1.000 26.87250  ? 12  VAL H CA  1 
ATOM   69   C C   . VAL A 1 12  ? 7.39157   5.81831  4.78855   1.000 30.60561  ? 12  VAL H C   1 
ATOM   70   O O   . VAL A 1 12  ? 7.26646   5.32976  5.91515   1.000 24.39535  ? 12  VAL H O   1 
ATOM   71   C CB  . VAL A 1 12  ? 8.89643   7.82567  4.86987   1.000 27.41762  ? 12  VAL H CB  1 
ATOM   72   C CG1 . VAL A 1 12  ? 9.84341   7.25385  3.82178   1.000 36.23039  ? 12  VAL H CG1 1 
ATOM   73   C CG2 . VAL A 1 12  ? 8.94839   9.35039  4.88372   1.000 38.92987  ? 12  VAL H CG2 1 
ATOM   74   N N   . GLN A 1 13  ? 7.52031   5.06245  3.68877   1.000 22.23824  ? 13  GLN H N   1 
ATOM   75   C CA  . GLN A 1 13  ? 7.46068   3.61959  3.90967   1.000 21.22178  ? 13  GLN H CA  1 
ATOM   76   C C   . GLN A 1 13  ? 8.81283   3.05611  4.35278   1.000 19.21825  ? 13  GLN H C   1 
ATOM   77   O O   . GLN A 1 13  ? 9.86877   3.57886  3.98252   1.000 24.27670  ? 13  GLN H O   1 
ATOM   78   C CB  . GLN A 1 13  ? 6.99744   2.89576  2.64616   1.000 31.27921  ? 13  GLN H CB  1 
ATOM   79   C CG  . GLN A 1 13  ? 5.52739   3.09556  2.33962   1.000 34.17622  ? 13  GLN H CG  1 
ATOM   80   C CD  . GLN A 1 13  ? 4.88494   1.89828  1.64645   1.000 51.21595  ? 13  GLN H CD  1 
ATOM   81   O OE1 . GLN A 1 13  ? 5.55223   1.12494  0.95353   1.000 55.39012  ? 13  GLN H OE1 1 
ATOM   82   N NE2 . GLN A 1 13  ? 3.57552   1.74135  1.83689   1.000 51.72469  ? 13  GLN H NE2 1 
ATOM   83   N N   . PRO A 1 14  ? 8.80549   1.98944  5.14869   1.000 22.09492  ? 14  PRO H N   1 
ATOM   84   C CA  . PRO A 1 14  ? 10.06429  1.33008  5.49839   1.000 22.99486  ? 14  PRO H CA  1 
ATOM   85   C C   . PRO A 1 14  ? 10.77882  0.88892  4.23342   1.000 25.89681  ? 14  PRO H C   1 
ATOM   86   O O   . PRO A 1 14  ? 10.15084  0.59388  3.21331   1.000 25.88698  ? 14  PRO H O   1 
ATOM   87   C CB  . PRO A 1 14  ? 9.62332   0.12758  6.34093   1.000 29.01728  ? 14  PRO H CB  1 
ATOM   88   C CG  . PRO A 1 14  ? 8.21978   0.43726  6.76472   1.000 32.00995  ? 14  PRO H CG  1 
ATOM   89   C CD  . PRO A 1 14  ? 7.63557   1.25620  5.66414   1.000 28.00586  ? 14  PRO H CD  1 
ATOM   90   N N   . GLY A 1 15  ? 12.10893  0.88270  4.29729   1.000 22.56926  ? 15  GLY H N   1 
ATOM   91   C CA  . GLY A 1 15  ? 12.91203  0.62070  3.12523   1.000 28.51642  ? 15  GLY H CA  1 
ATOM   92   C C   . GLY A 1 15  ? 13.03987  1.78250  2.16682   1.000 31.61024  ? 15  GLY H C   1 
ATOM   93   O O   . GLY A 1 15  ? 13.87620  1.72444  1.26045   1.000 33.78801  ? 15  GLY H O   1 
ATOM   94   N N   . GLY A 1 16  ? 12.24866  2.83425  2.33072   1.000 32.74504  ? 16  GLY H N   1 
ATOM   95   C CA  . GLY A 1 16  ? 12.30254  3.99027  1.46324   1.000 32.12132  ? 16  GLY H CA  1 
ATOM   96   C C   . GLY A 1 16  ? 13.34536  4.98337  1.92723   1.000 36.48058  ? 16  GLY H C   1 
ATOM   97   O O   . GLY A 1 16  ? 14.27835  4.65135  2.66581   1.000 24.53853  ? 16  GLY H O   1 
ATOM   98   N N   . SER A 1 17  ? 13.17476  6.22949  1.48903   1.000 35.73091  ? 17  SER H N   1 
ATOM   99   C CA  . SER A 1 17  ? 14.12370  7.28871  1.80064   1.000 40.00363  ? 17  SER H CA  1 
ATOM   100  C C   . SER A 1 17  ? 13.39291  8.53549  2.26454   1.000 30.67443  ? 17  SER H C   1 
ATOM   101  O O   . SER A 1 17  ? 12.27585  8.82514  1.83066   1.000 29.02314  ? 17  SER H O   1 
ATOM   102  C CB  . SER A 1 17  ? 15.00470  7.63668  0.59009   1.000 48.03857  ? 17  SER H CB  1 
ATOM   103  O OG  . SER A 1 17  ? 15.91581  6.58959  0.31916   1.000 47.89596  ? 17  SER H OG  1 
ATOM   104  N N   . LEU A 1 18  ? 14.02477  9.26310  3.17435   1.000 35.05984  ? 18  LEU H N   1 
ATOM   105  C CA  . LEU A 1 18  ? 13.57101  10.60219 3.50696   1.000 39.58035  ? 18  LEU H CA  1 
ATOM   106  C C   . LEU A 1 18  ? 14.51241  11.60480 2.85943   1.000 38.23693  ? 18  LEU H C   1 
ATOM   107  O O   . LEU A 1 18  ? 15.72777  11.37881 2.78677   1.000 34.90068  ? 18  LEU H O   1 
ATOM   108  C CB  . LEU A 1 18  ? 13.50488  10.83208 5.02281   1.000 31.39933  ? 18  LEU H CB  1 
ATOM   109  C CG  . LEU A 1 18  ? 14.75437  10.85174 5.90087   1.000 36.39236  ? 18  LEU H CG  1 
ATOM   110  C CD1 . LEU A 1 18  ? 15.48492  12.19217 5.87671   1.000 40.85085  ? 18  LEU H CD1 1 
ATOM   111  C CD2 . LEU A 1 18  ? 14.35543  10.50408 7.32385   1.000 36.50432  ? 18  LEU H CD2 1 
ATOM   112  N N   . ARG A 1 19  ? 13.94452  12.70829 2.38991   1.000 34.23594  ? 19  ARG H N   1 
ATOM   113  C CA  . ARG A 1 19  ? 14.73007  13.84132 1.92448   1.000 43.07576  ? 19  ARG H CA  1 
ATOM   114  C C   . ARG A 1 19  ? 14.18933  15.07945 2.61440   1.000 41.11459  ? 19  ARG H C   1 
ATOM   115  O O   . ARG A 1 19  ? 12.99976  15.38917 2.49576   1.000 36.87932  ? 19  ARG H O   1 
ATOM   116  C CB  . ARG A 1 19  ? 14.66828  13.98310 0.40021   1.000 49.92491  ? 19  ARG H CB  1 
ATOM   117  C CG  . ARG A 1 19  ? 15.76659  14.86496 -0.17715  1.000 63.01959  ? 19  ARG H CG  1 
ATOM   118  C CD  . ARG A 1 19  ? 16.04302  14.52416 -1.64035  1.000 75.77645  ? 19  ARG H CD  1 
ATOM   119  N NE  . ARG A 1 19  ? 15.65532  15.59762 -2.54927  1.000 79.46897  ? 19  ARG H NE  1 
ATOM   120  C CZ  . ARG A 1 19  ? 16.49340  16.49495 -3.05083  1.000 76.76075  ? 19  ARG H CZ  1 
ATOM   121  N NH1 . ARG A 1 19  ? 17.78417  16.47340 -2.76122  1.000 74.48338  ? 19  ARG H NH1 1 
ATOM   122  N NH2 . ARG A 1 19  ? 16.02481  17.43648 -3.86444  1.000 79.84361  ? 19  ARG H NH2 1 
ATOM   123  N N   . LEU A 1 20  ? 15.04771  15.76983 3.35366   1.000 34.42064  ? 20  LEU H N   1 
ATOM   124  C CA  . LEU A 1 20  ? 14.62643  16.93925 4.10409   1.000 37.05149  ? 20  LEU H CA  1 
ATOM   125  C C   . LEU A 1 20  ? 15.44338  18.14104 3.67068   1.000 34.78069  ? 20  LEU H C   1 
ATOM   126  O O   . LEU A 1 20  ? 16.65261  18.02847 3.45549   1.000 36.84710  ? 20  LEU H O   1 
ATOM   127  C CB  . LEU A 1 20  ? 14.78307  16.71787 5.60596   1.000 36.57769  ? 20  LEU H CB  1 
ATOM   128  C CG  . LEU A 1 20  ? 13.90885  15.59846 6.16438   1.000 43.89956  ? 20  LEU H CG  1 
ATOM   129  C CD1 . LEU A 1 20  ? 14.28860  15.36447 7.60260   1.000 39.40661  ? 20  LEU H CD1 1 
ATOM   130  C CD2 . LEU A 1 20  ? 12.43282  15.95148 6.03890   1.000 42.33897  ? 20  LEU H CD2 1 
ATOM   131  N N   . SER A 1 21  ? 14.77706  19.28920 3.56801   1.000 33.97282  ? 21  SER H N   1 
ATOM   132  C CA  . SER A 1 21  ? 15.42790  20.52784 3.17195   1.000 52.19813  ? 21  SER H CA  1 
ATOM   133  C C   . SER A 1 21  ? 14.94367  21.67674 4.04320   1.000 56.66760  ? 21  SER H C   1 
ATOM   134  O O   . SER A 1 21  ? 13.75870  21.76205 4.38174   1.000 52.94997  ? 21  SER H O   1 
ATOM   135  C CB  . SER A 1 21  ? 15.17662  20.84824 1.68942   1.000 39.51575  ? 21  SER H CB  1 
ATOM   136  O OG  . SER A 1 21  ? 16.08669  20.13578 0.86265   1.000 52.03034  ? 21  SER H OG  1 
ATOM   137  N N   . CYS A 1 22  ? 15.87849  22.55173 4.40681   1.000 58.21295  ? 22  CYS H N   1 
ATOM   138  C CA  . CYS A 1 22  ? 15.58505  23.78520 5.12019   1.000 61.47190  ? 22  CYS H CA  1 
ATOM   139  C C   . CYS A 1 22  ? 16.01305  24.95253 4.25294   1.000 59.19223  ? 22  CYS H C   1 
ATOM   140  O O   . CYS A 1 22  ? 17.15214  24.98545 3.78016   1.000 52.48365  ? 22  CYS H O   1 
ATOM   141  C CB  . CYS A 1 22  ? 16.31222  23.83932 6.46013   1.000 58.64146  ? 22  CYS H CB  1 
ATOM   142  S SG  . CYS A 1 22  ? 15.60294  22.75501 7.69259   1.000 77.58377  ? 22  CYS H SG  1 
ATOM   143  N N   . THR A 1 23  ? 15.10716  25.90163 4.04608   1.000 56.64182  ? 23  THR H N   1 
ATOM   144  C CA  . THR A 1 23  ? 15.38592  27.07282 3.22493   1.000 69.84079  ? 23  THR H CA  1 
ATOM   145  C C   . THR A 1 23  ? 15.63144  28.26902 4.13821   1.000 69.25813  ? 23  THR H C   1 
ATOM   146  O O   . THR A 1 23  ? 14.71255  28.74162 4.81790   1.000 62.28433  ? 23  THR H O   1 
ATOM   147  C CB  . THR A 1 23  ? 14.24396  27.34843 2.25094   1.000 68.53725  ? 23  THR H CB  1 
ATOM   148  O OG1 . THR A 1 23  ? 14.08970  26.22549 1.37384   1.000 68.77290  ? 23  THR H OG1 1 
ATOM   149  C CG2 . THR A 1 23  ? 14.55331  28.59036 1.42569   1.000 62.44402  ? 23  THR H CG2 1 
ATOM   150  N N   . ALA A 1 24  ? 16.87341  28.75238 4.14730   1.000 64.58897  ? 24  ALA H N   1 
ATOM   151  C CA  . ALA A 1 24  ? 17.22315  29.93744 4.91800   1.000 63.04654  ? 24  ALA H CA  1 
ATOM   152  C C   . ALA A 1 24  ? 16.50631  31.16729 4.37159   1.000 62.91881  ? 24  ALA H C   1 
ATOM   153  O O   . ALA A 1 24  ? 16.62044  31.49278 3.18423   1.000 63.42853  ? 24  ALA H O   1 
ATOM   154  C CB  . ALA A 1 24  ? 18.73345  30.15598 4.89142   1.000 55.46931  ? 24  ALA H CB  1 
ATOM   155  N N   . SER A 1 25  ? 15.77248  31.85363 5.24693   1.000 60.01828  ? 25  SER H N   1 
ATOM   156  C CA  . SER A 1 25  ? 15.04734  33.07466 4.90915   1.000 64.51726  ? 25  SER H CA  1 
ATOM   157  C C   . SER A 1 25  ? 15.66539  34.23114 5.68669   1.000 65.75076  ? 25  SER H C   1 
ATOM   158  O O   . SER A 1 25  ? 15.47469  34.33862 6.90345   1.000 68.87729  ? 25  SER H O   1 
ATOM   159  C CB  . SER A 1 25  ? 13.55898  32.92847 5.22423   1.000 62.00026  ? 25  SER H CB  1 
ATOM   160  O OG  . SER A 1 25  ? 12.86994  34.14695 5.00568   1.000 70.09930  ? 25  SER H OG  1 
ATOM   161  N N   . GLY A 1 26  ? 16.41110  35.08664 4.99089   1.000 59.16627  ? 26  GLY H N   1 
ATOM   162  C CA  . GLY A 1 26  ? 17.03700  36.23424 5.60885   1.000 53.08747  ? 26  GLY H CA  1 
ATOM   163  C C   . GLY A 1 26  ? 18.54119  36.16350 5.76746   1.000 47.31141  ? 26  GLY H C   1 
ATOM   164  O O   . GLY A 1 26  ? 19.09732  36.97114 6.52317   1.000 58.20284  ? 26  GLY H O   1 
ATOM   165  N N   . PHE A 1 27  ? 19.21618  35.23716 5.07826   1.000 45.95914  ? 27  PHE H N   1 
ATOM   166  C CA  . PHE A 1 27  ? 20.66993  35.08932 5.15045   1.000 54.45754  ? 27  PHE H CA  1 
ATOM   167  C C   . PHE A 1 27  ? 21.15133  33.99320 4.20220   1.000 49.42292  ? 27  PHE H C   1 
ATOM   168  O O   . PHE A 1 27  ? 20.33833  33.29644 3.58824   1.000 58.45718  ? 27  PHE H O   1 
ATOM   169  C CB  . PHE A 1 27  ? 21.11931  34.78108 6.58194   1.000 50.26690  ? 27  PHE H CB  1 
ATOM   170  C CG  . PHE A 1 27  ? 20.59675  33.47684 7.11119   1.000 50.46592  ? 27  PHE H CG  1 
ATOM   171  C CD1 . PHE A 1 27  ? 19.24647  33.31919 7.40059   1.000 47.77839  ? 27  PHE H CD1 1 
ATOM   172  C CD2 . PHE A 1 27  ? 21.45598  32.40721 7.31875   1.000 51.06810  ? 27  PHE H CD2 1 
ATOM   173  C CE1 . PHE A 1 27  ? 18.75918  32.11952 7.88230   1.000 51.77710  ? 27  PHE H CE1 1 
ATOM   174  C CE2 . PHE A 1 27  ? 20.97629  31.20403 7.80787   1.000 56.99615  ? 27  PHE H CE2 1 
ATOM   175  C CZ  . PHE A 1 27  ? 19.62498  31.06165 8.09077   1.000 44.86951  ? 27  PHE H CZ  1 
ATOM   176  N N   . SER A 1 28  ? 22.46461  33.82706 4.07858   1.000 51.71702  ? 28  SER H N   1 
ATOM   177  C CA  . SER A 1 28  ? 23.04920  32.85504 3.16391   1.000 62.58713  ? 28  SER H CA  1 
ATOM   178  C C   . SER A 1 28  ? 23.41746  31.58182 3.91468   1.000 62.37009  ? 28  SER H C   1 
ATOM   179  O O   . SER A 1 28  ? 23.99502  31.63962 5.00434   1.000 53.73802  ? 28  SER H O   1 
ATOM   180  C CB  . SER A 1 28  ? 24.28964  33.43092 2.47291   1.000 55.98777  ? 28  SER H CB  1 
ATOM   181  O OG  . SER A 1 28  ? 24.79447  32.53654 1.49071   1.000 50.24884  ? 28  SER H OG  1 
ATOM   182  N N   . ILE A 1 29  ? 23.09704  30.43013 3.31260   1.000 56.92053  ? 29  ILE H N   1 
ATOM   183  C CA  . ILE A 1 29  ? 23.28224  29.15224 3.99995   1.000 58.17124  ? 29  ILE H CA  1 
ATOM   184  C C   . ILE A 1 29  ? 24.75482  28.82884 4.21047   1.000 59.47359  ? 29  ILE H C   1 
ATOM   185  O O   . ILE A 1 29  ? 25.10312  28.09674 5.14558   1.000 58.83221  ? 29  ILE H O   1 
ATOM   186  C CB  . ILE A 1 29  ? 22.59414  28.00901 3.23438   1.000 65.23350  ? 29  ILE H CB  1 
ATOM   187  C CG1 . ILE A 1 29  ? 22.92539  28.09724 1.74438   1.000 62.55308  ? 29  ILE H CG1 1 
ATOM   188  C CG2 . ILE A 1 29  ? 21.10627  28.00637 3.49533   1.000 66.75102  ? 29  ILE H CG2 1 
ATOM   189  C CD1 . ILE A 1 29  ? 23.27380  26.76218 1.13119   1.000 67.64906  ? 29  ILE H CD1 1 
ATOM   190  N N   . ASP A 1 30  ? 25.64077  29.32461 3.34818   1.000 57.53151  ? 30  ASP H N   1 
ATOM   191  C CA  . ASP A 1 30  ? 27.05757  29.05347 3.55507   1.000 61.34863  ? 30  ASP H CA  1 
ATOM   192  C C   . ASP A 1 30  ? 27.68477  29.98641 4.58406   1.000 57.58934  ? 30  ASP H C   1 
ATOM   193  O O   . ASP A 1 30  ? 28.88180  29.84998 4.86828   1.000 55.75753  ? 30  ASP H O   1 
ATOM   194  C CB  . ASP A 1 30  ? 27.81833  29.12924 2.22677   1.000 64.84924  ? 30  ASP H CB  1 
ATOM   195  C CG  . ASP A 1 30  ? 27.87762  30.53028 1.66618   1.000 65.67807  ? 30  ASP H CG  1 
ATOM   196  O OD1 . ASP A 1 30  ? 28.82402  31.26557 2.02109   1.000 63.16170  ? 30  ASP H OD1 1 
ATOM   197  O OD2 . ASP A 1 30  ? 26.98099  30.89388 0.87191   1.000 74.07875  ? 30  ASP H OD2 1 
ATOM   198  N N   . SER A 1 31  ? 26.89953  30.91076 5.15408   1.000 53.27270  ? 31  SER H N   1 
ATOM   199  C CA  . SER A 1 31  ? 27.38898  31.74824 6.24635   1.000 51.05013  ? 31  SER H CA  1 
ATOM   200  C C   . SER A 1 31  ? 27.74855  30.91692 7.47126   1.000 53.29820  ? 31  SER H C   1 
ATOM   201  O O   . SER A 1 31  ? 28.76779  31.17244 8.12131   1.000 51.14170  ? 31  SER H O   1 
ATOM   202  C CB  . SER A 1 31  ? 26.34284  32.79418 6.62354   1.000 49.33032  ? 31  SER H CB  1 
ATOM   203  O OG  . SER A 1 31  ? 25.75645  33.37652 5.47395   1.000 53.91460  ? 31  SER H OG  1 
ATOM   204  N N   . TYR A 1 32  ? 26.92789  29.92327 7.80758   1.000 51.66304  ? 32  TYR H N   1 
ATOM   205  C CA  . TYR A 1 32  ? 27.09824  29.17173 9.04177   1.000 49.88243  ? 32  TYR H CA  1 
ATOM   206  C C   . TYR A 1 32  ? 27.14540  27.67773 8.75780   1.000 52.55880  ? 32  TYR H C   1 
ATOM   207  O O   . TYR A 1 32  ? 26.60631  27.19948 7.75814   1.000 49.35610  ? 32  TYR H O   1 
ATOM   208  C CB  . TYR A 1 32  ? 25.95911  29.44546 10.02711  1.000 45.60660  ? 32  TYR H CB  1 
ATOM   209  C CG  . TYR A 1 32  ? 25.58533  30.89877 10.20190  1.000 44.68547  ? 32  TYR H CG  1 
ATOM   210  C CD1 . TYR A 1 32  ? 26.43313  31.78323 10.86269  1.000 41.03978  ? 32  TYR H CD1 1 
ATOM   211  C CD2 . TYR A 1 32  ? 24.36442  31.38205 9.73908   1.000 40.24552  ? 32  TYR H CD2 1 
ATOM   212  C CE1 . TYR A 1 32  ? 26.08240  33.11738 11.03747  1.000 38.77633  ? 32  TYR H CE1 1 
ATOM   213  C CE2 . TYR A 1 32  ? 24.00690  32.70687 9.91676   1.000 41.48359  ? 32  TYR H CE2 1 
ATOM   214  C CZ  . TYR A 1 32  ? 24.86999  33.56832 10.56700  1.000 46.71433  ? 32  TYR H CZ  1 
ATOM   215  O OH  . TYR A 1 32  ? 24.51925  34.88727 10.74433  1.000 53.82606  ? 32  TYR H OH  1 
ATOM   216  N N   . GLY A 1 33  ? 27.79476  26.94330 9.66153   1.000 43.91446  ? 33  GLY H N   1 
ATOM   217  C CA  . GLY A 1 33  ? 27.65710  25.49537 9.67890   1.000 49.33004  ? 33  GLY H CA  1 
ATOM   218  C C   . GLY A 1 33  ? 26.30555  25.08628 10.25393  1.000 48.94334  ? 33  GLY H C   1 
ATOM   219  O O   . GLY A 1 33  ? 25.78834  25.70620 11.18540  1.000 43.08310  ? 33  GLY H O   1 
ATOM   220  N N   . PHE A 1 34  ? 25.73134  24.02419 9.67670   1.000 48.15044  ? 34  PHE H N   1 
ATOM   221  C CA  . PHE A 1 34  ? 24.40038  23.54356 10.03937  1.000 40.74257  ? 34  PHE H CA  1 
ATOM   222  C C   . PHE A 1 34  ? 24.42154  22.06237 10.37740  1.000 47.78570  ? 34  PHE H C   1 
ATOM   223  O O   . PHE A 1 34  ? 25.00528  21.25420 9.64419   1.000 41.84665  ? 34  PHE H O   1 
ATOM   224  C CB  . PHE A 1 34  ? 23.39118  23.78352 8.92691   1.000 36.00467  ? 34  PHE H CB  1 
ATOM   225  C CG  . PHE A 1 34  ? 22.90558  25.18933 8.86375   1.000 49.82503  ? 34  PHE H CG  1 
ATOM   226  C CD1 . PHE A 1 34  ? 21.89891  25.62263 9.70969   1.000 43.83136  ? 34  PHE H CD1 1 
ATOM   227  C CD2 . PHE A 1 34  ? 23.46233  26.08955 7.96944   1.000 50.27004  ? 34  PHE H CD2 1 
ATOM   228  C CE1 . PHE A 1 34  ? 21.44538  26.92693 9.65886   1.000 48.58251  ? 34  PHE H CE1 1 
ATOM   229  C CE2 . PHE A 1 34  ? 23.01307  27.39558 7.91008   1.000 49.82433  ? 34  PHE H CE2 1 
ATOM   230  C CZ  . PHE A 1 34  ? 22.00214  27.81563 8.75726   1.000 52.19893  ? 34  PHE H CZ  1 
ATOM   231  N N   . SER A 1 35  ? 23.76017  21.71668 11.47490  1.000 40.14805  ? 35  SER H N   1 
ATOM   232  C CA  . SER A 1 35  ? 23.59128  20.34116 11.90338  1.000 35.37913  ? 35  SER H CA  1 
ATOM   233  C C   . SER A 1 35  ? 22.21272  19.82170 11.50945  1.000 30.23779  ? 35  SER H C   1 
ATOM   234  O O   . SER A 1 35  ? 21.27799  20.58076 11.24757  1.000 31.45504  ? 35  SER H O   1 
ATOM   235  C CB  . SER A 1 35  ? 23.77110  20.22254 13.41601  1.000 32.09360  ? 35  SER H CB  1 
ATOM   236  O OG  . SER A 1 35  ? 25.12831  20.29605 13.78780  1.000 34.61670  ? 35  SER H OG  1 
ATOM   237  N N   . TRP A 1 36  ? 22.09763  18.50182 11.46495  1.000 34.85666  ? 36  TRP H N   1 
ATOM   238  C CA  . TRP A 1 36  ? 20.80112  17.84707 11.43692  1.000 31.06642  ? 36  TRP H CA  1 
ATOM   239  C C   . TRP A 1 36  ? 20.67908  17.04769 12.71651  1.000 23.56252  ? 36  TRP H C   1 
ATOM   240  O O   . TRP A 1 36  ? 21.63629  16.39297 13.13823  1.000 27.80057  ? 36  TRP H O   1 
ATOM   241  C CB  . TRP A 1 36  ? 20.62425  16.94660 10.21578  1.000 34.69513  ? 36  TRP H CB  1 
ATOM   242  C CG  . TRP A 1 36  ? 20.31810  17.70813 8.96320   1.000 34.78837  ? 36  TRP H CG  1 
ATOM   243  C CD1 . TRP A 1 36  ? 21.21016  18.10096 8.00271   1.000 34.21780  ? 36  TRP H CD1 1 
ATOM   244  C CD2 . TRP A 1 36  ? 19.03568  18.18706 8.53740   1.000 30.06823  ? 36  TRP H CD2 1 
ATOM   245  N NE1 . TRP A 1 36  ? 20.55731  18.77856 7.00366   1.000 37.79733  ? 36  TRP H NE1 1 
ATOM   246  C CE2 . TRP A 1 36  ? 19.22535  18.85278 7.30952   1.000 29.39146  ? 36  TRP H CE2 1 
ATOM   247  C CE3 . TRP A 1 36  ? 17.74554  18.10957 9.06799   1.000 28.91622  ? 36  TRP H CE3 1 
ATOM   248  C CZ2 . TRP A 1 36  ? 18.17478  19.42099 6.59955   1.000 29.28100  ? 36  TRP H CZ2 1 
ATOM   249  C CZ3 . TRP A 1 36  ? 16.70388  18.68720 8.36971   1.000 25.10325  ? 36  TRP H CZ3 1 
ATOM   250  C CH2 . TRP A 1 36  ? 16.92484  19.33797 7.14630   1.000 32.10788  ? 36  TRP H CH2 1 
ATOM   251  N N   . VAL A 1 37  ? 19.51932  17.15072 13.35214  1.000 26.38980  ? 37  VAL H N   1 
ATOM   252  C CA  . VAL A 1 37  ? 19.26771  16.54787 14.65058  1.000 29.09010  ? 37  VAL H CA  1 
ATOM   253  C C   . VAL A 1 37  ? 17.91238  15.86365 14.58056  1.000 23.18681  ? 37  VAL H C   1 
ATOM   254  O O   . VAL A 1 37  ? 17.02091  16.30301 13.85456  1.000 21.23228  ? 37  VAL H O   1 
ATOM   255  C CB  . VAL A 1 37  ? 19.29783  17.60448 15.78310  1.000 30.67449  ? 37  VAL H CB  1 
ATOM   256  C CG1 . VAL A 1 37  ? 18.92817  16.97373 17.12280  1.000 31.63506  ? 37  VAL H CG1 1 
ATOM   257  C CG2 . VAL A 1 37  ? 20.67698  18.26018 15.86906  1.000 26.29578  ? 37  VAL H CG2 1 
ATOM   258  N N   . ARG A 1 38  ? 17.74822  14.78534 15.33958  1.000 24.37893  ? 38  ARG H N   1 
ATOM   259  C CA  . ARG A 1 38  ? 16.44141  14.15068 15.38009  1.000 24.17439  ? 38  ARG H CA  1 
ATOM   260  C C   . ARG A 1 38  ? 16.13399  13.70865 16.80152  1.000 21.77931  ? 38  ARG H C   1 
ATOM   261  O O   . ARG A 1 38  ? 17.02335  13.56640 17.64267  1.000 22.82526  ? 38  ARG H O   1 
ATOM   262  C CB  . ARG A 1 38  ? 16.36652  12.96671 14.41548  1.000 22.53933  ? 38  ARG H CB  1 
ATOM   263  C CG  . ARG A 1 38  ? 17.19270  11.77342 14.84620  1.000 26.31255  ? 38  ARG H CG  1 
ATOM   264  C CD  . ARG A 1 38  ? 17.04098  10.63498 13.85351  1.000 28.58130  ? 38  ARG H CD  1 
ATOM   265  N NE  . ARG A 1 38  ? 17.51788  9.36669  14.39379  1.000 32.31431  ? 38  ARG H NE  1 
ATOM   266  C CZ  . ARG A 1 38  ? 17.53651  8.23310  13.70735  1.000 31.30273  ? 38  ARG H CZ  1 
ATOM   267  N NH1 . ARG A 1 38  ? 17.16526  8.19138  12.43711  1.000 32.19595  ? 38  ARG H NH1 1 
ATOM   268  N NH2 . ARG A 1 38  ? 17.92256  7.11403  14.31323  1.000 31.80156  ? 38  ARG H NH2 1 
ATOM   269  N N   . GLN A 1 39  ? 14.85156  13.47604 17.04619  1.000 25.88053  ? 39  GLN H N   1 
ATOM   270  C CA  . GLN A 1 39  ? 14.34262  13.13553 18.37053  1.000 21.72119  ? 39  GLN H CA  1 
ATOM   271  C C   . GLN A 1 39  ? 13.18879  12.16514 18.17307  1.000 21.14759  ? 39  GLN H C   1 
ATOM   272  O O   . GLN A 1 39  ? 12.11448  12.57637 17.72543  1.000 17.64652  ? 39  GLN H O   1 
ATOM   273  C CB  . GLN A 1 39  ? 13.87438  14.39030 19.10650  1.000 19.39952  ? 39  GLN H CB  1 
ATOM   274  C CG  . GLN A 1 39  ? 13.25297  14.14601 20.46531  1.000 21.67484  ? 39  GLN H CG  1 
ATOM   275  C CD  . GLN A 1 39  ? 13.13179  15.42292 21.26022  1.000 27.53845  ? 39  GLN H CD  1 
ATOM   276  O OE1 . GLN A 1 39  ? 12.69924  16.44989 20.73625  1.000 20.28845  ? 39  GLN H OE1 1 
ATOM   277  N NE2 . GLN A 1 39  ? 13.51240  15.36982 22.53581  1.000 24.68340  ? 39  GLN H NE2 1 
ATOM   278  N N   . ALA A 1 40  ? 13.40618  10.88896 18.47821  1.000 22.10940  ? 40  ALA H N   1 
ATOM   279  C CA  . ALA A 1 40  ? 12.30495  9.93779  18.41450  1.000 25.01604  ? 40  ALA H CA  1 
ATOM   280  C C   . ALA A 1 40  ? 11.28276  10.25479 19.51146  1.000 25.50983  ? 40  ALA H C   1 
ATOM   281  O O   . ALA A 1 40  ? 11.63463  10.79834 20.56414  1.000 25.72473  ? 40  ALA H O   1 
ATOM   282  C CB  . ALA A 1 40  ? 12.81876  8.50287  18.54719  1.000 22.39159  ? 40  ALA H CB  1 
ATOM   283  N N   . PRO A 1 41  ? 10.00646  9.95489  19.28108  1.000 31.02120  ? 41  PRO H N   1 
ATOM   284  C CA  . PRO A 1 41  ? 8.98127   10.31050 20.27236  1.000 28.70537  ? 41  PRO H CA  1 
ATOM   285  C C   . PRO A 1 41  ? 9.33121   9.79174  21.66578  1.000 30.93320  ? 41  PRO H C   1 
ATOM   286  O O   . PRO A 1 41  ? 9.69335   8.62632  21.84691  1.000 28.69569  ? 41  PRO H O   1 
ATOM   287  C CB  . PRO A 1 41  ? 7.71724   9.64939  19.71510  1.000 34.26229  ? 41  PRO H CB  1 
ATOM   288  C CG  . PRO A 1 41  ? 7.96340   9.60890  18.21345  1.000 33.88951  ? 41  PRO H CG  1 
ATOM   289  C CD  . PRO A 1 41  ? 9.42731   9.31365  18.07913  1.000 32.55705  ? 41  PRO H CD  1 
ATOM   290  N N   . GLY A 1 42  ? 9.28250   10.69063 22.64655  1.000 30.81930  ? 42  GLY H N   1 
ATOM   291  C CA  . GLY A 1 42  ? 9.62245   10.36697 24.01552  1.000 32.74685  ? 42  GLY H CA  1 
ATOM   292  C C   . GLY A 1 42  ? 11.09774  10.22831 24.33894  1.000 32.91076  ? 42  GLY H C   1 
ATOM   293  O O   . GLY A 1 42  ? 11.42744  9.94145  25.49388  1.000 32.09672  ? 42  GLY H O   1 
ATOM   294  N N   . LYS A 1 43  ? 11.99922  10.40718 23.38100  1.000 27.71576  ? 43  LYS H N   1 
ATOM   295  C CA  . LYS A 1 43  ? 13.41817  10.16336 23.61693  1.000 28.16729  ? 43  LYS H CA  1 
ATOM   296  C C   . LYS A 1 43  ? 14.19084  11.47476 23.53872  1.000 21.83233  ? 43  LYS H C   1 
ATOM   297  O O   . LYS A 1 43  ? 13.61242  12.54971 23.34786  1.000 25.64943  ? 43  LYS H O   1 
ATOM   298  C CB  . LYS A 1 43  ? 13.97267  9.14365  22.61842  1.000 22.76188  ? 43  LYS H CB  1 
ATOM   299  C CG  . LYS A 1 43  ? 13.13014  7.87333  22.47079  1.000 32.04947  ? 43  LYS H CG  1 
ATOM   300  C CD  . LYS A 1 43  ? 13.19094  6.98098  23.70204  1.000 35.95922  ? 43  LYS H CD  1 
ATOM   301  C CE  . LYS A 1 43  ? 12.39736  5.68363  23.49932  1.000 43.39243  ? 43  LYS H CE  1 
ATOM   302  N NZ  . LYS A 1 43  ? 11.94704  5.07598  24.80292  1.000 48.01481  ? 43  LYS H NZ  1 
ATOM   303  N N   . GLY A 1 44  ? 15.51962  11.36729 23.66231  1.000 26.86714  ? 44  GLY H N   1 
ATOM   304  C CA  . GLY A 1 44  ? 16.39224  12.52573 23.66503  1.000 28.38542  ? 44  GLY H CA  1 
ATOM   305  C C   . GLY A 1 44  ? 16.85131  12.94899 22.27334  1.000 29.20826  ? 44  GLY H C   1 
ATOM   306  O O   . GLY A 1 44  ? 16.47888  12.37280 21.25031  1.000 30.26471  ? 44  GLY H O   1 
ATOM   307  N N   . LEU A 1 45  ? 17.67987  13.99377 22.25674  1.000 26.92426  ? 45  LEU H N   1 
ATOM   308  C CA  . LEU A 1 45  ? 18.17308  14.58488 21.01745  1.000 25.23266  ? 45  LEU H CA  1 
ATOM   309  C C   . LEU A 1 45  ? 19.38451  13.82263 20.49964  1.000 29.42558  ? 45  LEU H C   1 
ATOM   310  O O   . LEU A 1 45  ? 20.26601  13.43671 21.26728  1.000 31.37009  ? 45  LEU H O   1 
ATOM   311  C CB  . LEU A 1 45  ? 18.54023  16.05380 21.24127  1.000 23.31940  ? 45  LEU H CB  1 
ATOM   312  C CG  . LEU A 1 45  ? 17.38028  16.98311 21.61760  1.000 34.97312  ? 45  LEU H CG  1 
ATOM   313  C CD1 . LEU A 1 45  ? 17.87558  18.34086 22.12452  1.000 27.60771  ? 45  LEU H CD1 1 
ATOM   314  C CD2 . LEU A 1 45  ? 16.45784  17.16175 20.43078  1.000 28.98985  ? 45  LEU H CD2 1 
ATOM   315  N N   . GLU A 1 46  ? 19.42092  13.60609 19.18654  1.000 28.05468  ? 46  GLU H N   1 
ATOM   316  C CA  . GLU A 1 46  ? 20.45632  12.80945 18.53688  1.000 30.63382  ? 46  GLU H CA  1 
ATOM   317  C C   . GLU A 1 46  ? 21.04045  13.61756 17.38309  1.000 30.75913  ? 46  GLU H C   1 
ATOM   318  O O   . GLU A 1 46  ? 20.30272  14.05781 16.49522  1.000 24.72619  ? 46  GLU H O   1 
ATOM   319  C CB  . GLU A 1 46  ? 19.86559  11.48526 18.03070  1.000 38.54820  ? 46  GLU H CB  1 
ATOM   320  C CG  . GLU A 1 46  ? 20.85970  10.43346 17.55937  1.000 41.44775  ? 46  GLU H CG  1 
ATOM   321  C CD  . GLU A 1 46  ? 20.17970  9.10091  17.19291  1.000 55.29397  ? 46  GLU H CD  1 
ATOM   322  O OE1 . GLU A 1 46  ? 18.92900  9.06149  17.10373  1.000 43.45996  ? 46  GLU H OE1 1 
ATOM   323  O OE2 . GLU A 1 46  ? 20.89869  8.09348  16.99801  1.000 56.86758  ? 46  GLU H OE2 1 
ATOM   324  N N   . HIS A 1 47  ? 22.35840  13.80915 17.39000  1.000 29.81192  ? 47  HIS H N   1 
ATOM   325  C CA  . HIS A 1 47  ? 23.01617  14.53090 16.30747  1.000 29.88981  ? 47  HIS H CA  1 
ATOM   326  C C   . HIS A 1 47  ? 23.24028  13.58708 15.13104  1.000 30.31573  ? 47  HIS H C   1 
ATOM   327  O O   . HIS A 1 47  ? 23.74834  12.47464 15.30081  1.000 39.97740  ? 47  HIS H O   1 
ATOM   328  C CB  . HIS A 1 47  ? 24.34397  15.12979 16.78895  1.000 34.28329  ? 47  HIS H CB  1 
ATOM   329  C CG  . HIS A 1 47  ? 25.02963  15.98988 15.76863  1.000 38.78092  ? 47  HIS H CG  1 
ATOM   330  N ND1 . HIS A 1 47  ? 26.21794  15.62880 15.16616  1.000 42.71584  ? 47  HIS H ND1 1 
ATOM   331  C CD2 . HIS A 1 47  ? 24.70017  17.19925 15.25432  1.000 35.60536  ? 47  HIS H CD2 1 
ATOM   332  C CE1 . HIS A 1 47  ? 26.58454  16.57367 14.31840  1.000 39.80684  ? 47  HIS H CE1 1 
ATOM   333  N NE2 . HIS A 1 47  ? 25.68156  17.53778 14.35383  1.000 41.86911  ? 47  HIS H NE2 1 
ATOM   334  N N   . ILE A 1 48  ? 22.82989  14.01910 13.94532  1.000 31.21468  ? 48  ILE H N   1 
ATOM   335  C CA  . ILE A 1 48  ? 22.95161  13.20592 12.74201  1.000 31.18919  ? 48  ILE H CA  1 
ATOM   336  C C   . ILE A 1 48  ? 24.27703  13.52556 12.05806  1.000 42.46143  ? 48  ILE H C   1 
ATOM   337  O O   . ILE A 1 48  ? 25.14796  12.65880 11.92045  1.000 38.23426  ? 48  ILE H O   1 
ATOM   338  C CB  . ILE A 1 48  ? 21.75300  13.44610 11.80895  1.000 32.30511  ? 48  ILE H CB  1 
ATOM   339  C CG1 . ILE A 1 48  ? 20.44662  13.04820 12.52703  1.000 25.97126  ? 48  ILE H CG1 1 
ATOM   340  C CG2 . ILE A 1 48  ? 21.93212  12.70812 10.47309  1.000 34.46115  ? 48  ILE H CG2 1 
ATOM   341  C CD1 . ILE A 1 48  ? 19.22327  13.13436 11.63577  1.000 25.27494  ? 48  ILE H CD1 1 
ATOM   342  N N   . GLY A 1 49  ? 24.44470  14.77452 11.64290  1.000 40.56221  ? 49  GLY H N   1 
ATOM   343  C CA  . GLY A 1 49  ? 25.71367  15.20152 11.08137  1.000 41.59671  ? 49  GLY H CA  1 
ATOM   344  C C   . GLY A 1 49  ? 25.77451  16.70605 10.94332  1.000 40.54512  ? 49  GLY H C   1 
ATOM   345  O O   . GLY A 1 49  ? 24.76235  17.40788 11.04213  1.000 40.53405  ? 49  GLY H O   1 
ATOM   346  N N   . TYR A 1 50  ? 26.99177  17.18447 10.67732  1.000 42.87317  ? 50  TYR H N   1 
ATOM   347  C CA  . TYR A 1 50  ? 27.30840  18.60478 10.59366  1.000 40.34851  ? 50  TYR H CA  1 
ATOM   348  C C   . TYR A 1 50  ? 27.88963  18.92383 9.22200   1.000 42.36327  ? 50  TYR H C   1 
ATOM   349  O O   . TYR A 1 50  ? 28.81741  18.24749 8.76519   1.000 44.44104  ? 50  TYR H O   1 
ATOM   350  C CB  . TYR A 1 50  ? 28.30923  18.98626 11.68951  1.000 40.17697  ? 50  TYR H CB  1 
ATOM   351  C CG  . TYR A 1 50  ? 28.58130  20.47043 11.83219  1.000 43.30496  ? 50  TYR H CG  1 
ATOM   352  C CD1 . TYR A 1 50  ? 27.53548  21.38752 11.89400  1.000 43.41036  ? 50  TYR H CD1 1 
ATOM   353  C CD2 . TYR A 1 50  ? 29.88571  20.95243 11.94340  1.000 43.41830  ? 50  TYR H CD2 1 
ATOM   354  C CE1 . TYR A 1 50  ? 27.77249  22.74314 12.04481  1.000 34.95386  ? 50  TYR H CE1 1 
ATOM   355  C CE2 . TYR A 1 50  ? 30.13254  22.30985 12.09852  1.000 41.94049  ? 50  TYR H CE2 1 
ATOM   356  C CZ  . TYR A 1 50  ? 29.07032  23.19674 12.14191  1.000 46.42619  ? 50  TYR H CZ  1 
ATOM   357  O OH  . TYR A 1 50  ? 29.30487  24.54252 12.29744  1.000 56.76633  ? 50  TYR H OH  1 
ATOM   358  N N   . LEU A 1 51  ? 27.35113  19.94713 8.57086   1.000 40.67451  ? 51  LEU H N   1 
ATOM   359  C CA  . LEU A 1 51  ? 27.94131  20.50563 7.35550   1.000 41.67971  ? 51  LEU H CA  1 
ATOM   360  C C   . LEU A 1 51  ? 28.60897  21.83708 7.71651   1.000 45.94411  ? 51  LEU H C   1 
ATOM   361  O O   . LEU A 1 51  ? 27.92901  22.86045 7.84618   1.000 45.84570  ? 51  LEU H O   1 
ATOM   362  C CB  . LEU A 1 51  ? 26.88693  20.68962 6.26869   1.000 36.39595  ? 51  LEU H CB  1 
ATOM   363  C CG  . LEU A 1 51  ? 27.44934  21.17093 4.93086   1.000 49.68065  ? 51  LEU H CG  1 
ATOM   364  C CD1 . LEU A 1 51  ? 28.40700  20.12836 4.35361   1.000 49.42414  ? 51  LEU H CD1 1 
ATOM   365  C CD2 . LEU A 1 51  ? 26.33316  21.49277 3.95222   1.000 43.60496  ? 51  LEU H CD2 1 
ATOM   366  N N   . THR A 1 52  ? 29.93801  21.82371 7.87844   1.000 43.99265  ? 52  THR H N   1 
ATOM   367  C CA  . THR A 1 52  ? 30.65473  23.04159 8.24965   1.000 48.20527  ? 52  THR H CA  1 
ATOM   368  C C   . THR A 1 52  ? 30.50729  24.09619 7.16208   1.000 41.45453  ? 52  THR H C   1 
ATOM   369  O O   . THR A 1 52  ? 30.38507  23.78163 5.97728   1.000 46.83686  ? 52  THR H O   1 
ATOM   370  C CB  . THR A 1 52  ? 32.14559  22.77448 8.48231   1.000 47.65613  ? 52  THR H CB  1 
ATOM   371  O OG1 . THR A 1 52  ? 32.78156  22.47063 7.23700   1.000 52.49297  ? 52  THR H OG1 1 
ATOM   372  C CG2 . THR A 1 52  ? 32.36258  21.62632 9.45613   1.000 59.37786  ? 52  THR H CG2 1 
ATOM   373  N N   . ALA A 1 53  ? 30.52332  25.36409 7.57991   1.000 45.74166  ? 53  ALA H N   1 
ATOM   374  C CA  . ALA A 1 53  ? 30.41743  26.46542 6.62858   1.000 56.41632  ? 53  ALA H CA  1 
ATOM   375  C C   . ALA A 1 53  ? 31.50606  26.40280 5.56209   1.000 52.43655  ? 53  ALA H C   1 
ATOM   376  O O   . ALA A 1 53  ? 31.30057  26.90850 4.45112   1.000 49.61280  ? 53  ALA H O   1 
ATOM   377  C CB  . ALA A 1 53  ? 30.46198  27.80553 7.36783   1.000 58.40854  ? 53  ALA H CB  1 
ATOM   378  N N   . GLY A 1 54  ? 32.64548  25.77616 5.87147   1.000 46.52274  ? 54  GLY H N   1 
ATOM   379  C CA  . GLY A 1 54  ? 33.65820  25.44729 4.88066   1.000 61.76868  ? 54  GLY H CA  1 
ATOM   380  C C   . GLY A 1 54  ? 33.23892  24.40001 3.86035   1.000 63.35386  ? 54  GLY H C   1 
ATOM   381  O O   . GLY A 1 54  ? 33.93856  24.23546 2.85531   1.000 69.84557  ? 54  GLY H O   1 
ATOM   382  N N   . GLY A 1 55  ? 32.13509  23.68154 4.09839   1.000 63.91743  ? 55  GLY H N   1 
ATOM   383  C CA  . GLY A 1 55  ? 31.55465  22.78503 3.11623   1.000 55.43573  ? 55  GLY H CA  1 
ATOM   384  C C   . GLY A 1 55  ? 31.80509  21.30581 3.33772   1.000 51.98407  ? 55  GLY H C   1 
ATOM   385  O O   . GLY A 1 55  ? 31.24464  20.49152 2.59630   1.000 50.66483  ? 55  GLY H O   1 
ATOM   386  N N   . ARG A 1 56  ? 32.63130  20.93371 4.31740   1.000 44.27998  ? 56  ARG H N   1 
ATOM   387  C CA  . ARG A 1 56  ? 32.89551  19.52795 4.60609   1.000 50.37464  ? 56  ARG H CA  1 
ATOM   388  C C   . ARG A 1 56  ? 31.80112  18.95885 5.50610   1.000 56.44059  ? 56  ARG H C   1 
ATOM   389  O O   . ARG A 1 56  ? 31.45432  19.55206 6.53270   1.000 59.77086  ? 56  ARG H O   1 
ATOM   390  C CB  . ARG A 1 56  ? 34.26504  19.35140 5.27064   1.000 46.63009  ? 56  ARG H CB  1 
ATOM   391  C CG  . ARG A 1 56  ? 35.45745  19.63389 4.36420   1.000 46.77952  ? 56  ARG H CG  1 
ATOM   392  C CD  . ARG A 1 56  ? 36.77932  19.24636 5.02562   1.000 36.66197  ? 56  ARG H CD  1 
ATOM   393  N NE  . ARG A 1 56  ? 37.20625  20.22270 6.02085   1.000 53.36877  ? 56  ARG H NE  1 
ATOM   394  C CZ  . ARG A 1 56  ? 38.23451  20.06137 6.84485   1.000 64.88408  ? 56  ARG H CZ  1 
ATOM   395  N NH1 . ARG A 1 56  ? 38.98118  18.96756 6.81659   1.000 64.65264  ? 56  ARG H NH1 1 
ATOM   396  N NH2 . ARG A 1 56  ? 38.51908  21.02060 7.72295   1.000 59.36229  ? 56  ARG H NH2 1 
ATOM   397  N N   . ALA A 1 57  ? 31.25869  17.80861 5.12325   1.000 50.09251  ? 57  ALA H N   1 
ATOM   398  C CA  . ALA A 1 57  ? 30.21436  17.14715 5.89320   1.000 51.34996  ? 57  ALA H CA  1 
ATOM   399  C C   . ALA A 1 57  ? 30.83744  16.07250 6.77494   1.000 56.00923  ? 57  ALA H C   1 
ATOM   400  O O   . ALA A 1 57  ? 31.66285  15.28007 6.30779   1.000 54.89704  ? 57  ALA H O   1 
ATOM   401  C CB  . ALA A 1 57  ? 29.15982  16.53801 4.96866   1.000 46.52432  ? 57  ALA H CB  1 
ATOM   402  N N   . PHE A 1 58  ? 30.45650  16.05831 8.04842   1.000 41.82836  ? 58  PHE H N   1 
ATOM   403  C CA  . PHE A 1 58  ? 30.86796  15.01378 8.97127   1.000 51.80492  ? 58  PHE H CA  1 
ATOM   404  C C   . PHE A 1 58  ? 29.63295  14.39272 9.61057   1.000 52.96356  ? 58  PHE H C   1 
ATOM   405  O O   . PHE A 1 58  ? 28.62754  15.07001 9.84305   1.000 48.86135  ? 58  PHE H O   1 
ATOM   406  C CB  . PHE A 1 58  ? 31.81482  15.55854 10.05150  1.000 57.80980  ? 58  PHE H CB  1 
ATOM   407  C CG  . PHE A 1 58  ? 33.07164  16.18016 9.49975   1.000 60.25479  ? 58  PHE H CG  1 
ATOM   408  C CD1 . PHE A 1 58  ? 33.09874  17.51671 9.13725   1.000 56.92939  ? 58  PHE H CD1 1 
ATOM   409  C CD2 . PHE A 1 58  ? 34.22255  15.42720 9.34075   1.000 60.31687  ? 58  PHE H CD2 1 
ATOM   410  C CE1 . PHE A 1 58  ? 34.25111  18.09143 8.63055   1.000 58.01161  ? 58  PHE H CE1 1 
ATOM   411  C CE2 . PHE A 1 58  ? 35.37635  15.99834 8.83109   1.000 65.36194  ? 58  PHE H CE2 1 
ATOM   412  C CZ  . PHE A 1 58  ? 35.38994  17.33143 8.47840   1.000 60.43583  ? 58  PHE H CZ  1 
ATOM   413  N N   . TYR A 1 59  ? 29.71619  13.09591 9.89333   1.000 49.74830  ? 59  TYR H N   1 
ATOM   414  C CA  . TYR A 1 59  ? 28.57387  12.32951 10.35898  1.000 49.61483  ? 59  TYR H CA  1 
ATOM   415  C C   . TYR A 1 59  ? 28.93396  11.60464 11.64250  1.000 51.20159  ? 59  TYR H C   1 
ATOM   416  O O   . TYR A 1 59  ? 30.08113  11.19535 11.84116  1.000 59.40328  ? 59  TYR H O   1 
ATOM   417  C CB  . TYR A 1 59  ? 28.11941  11.31272 9.30396   1.000 47.37540  ? 59  TYR H CB  1 
ATOM   418  C CG  . TYR A 1 59  ? 27.86373  11.92863 7.95218   1.000 45.43623  ? 59  TYR H CG  1 
ATOM   419  C CD1 . TYR A 1 59  ? 28.88038  12.04435 7.01234   1.000 52.58333  ? 59  TYR H CD1 1 
ATOM   420  C CD2 . TYR A 1 59  ? 26.60877  12.40270 7.61744   1.000 39.25546  ? 59  TYR H CD2 1 
ATOM   421  C CE1 . TYR A 1 59  ? 28.64409  12.62059 5.76922   1.000 44.45928  ? 59  TYR H CE1 1 
ATOM   422  C CE2 . TYR A 1 59  ? 26.36325  12.98041 6.39050   1.000 39.65803  ? 59  TYR H CE2 1 
ATOM   423  C CZ  . TYR A 1 59  ? 27.38529  13.08616 5.46416   1.000 44.28647  ? 59  TYR H CZ  1 
ATOM   424  O OH  . TYR A 1 59  ? 27.12837  13.66280 4.23558   1.000 43.69982  ? 59  TYR H OH  1 
ATOM   425  N N   . ALA A 1 60  ? 27.94647  11.45889 12.52167  1.000 47.90898  ? 60  ALA H N   1 
ATOM   426  C CA  . ALA A 1 60  ? 28.11046  10.54429 13.64085  1.000 51.76633  ? 60  ALA H CA  1 
ATOM   427  C C   . ALA A 1 60  ? 28.24335  9.12250  13.10742  1.000 51.79587  ? 60  ALA H C   1 
ATOM   428  O O   . ALA A 1 60  ? 27.72008  8.78530  12.03986  1.000 44.96305  ? 60  ALA H O   1 
ATOM   429  C CB  . ALA A 1 60  ? 26.92801  10.65102 14.60813  1.000 52.82680  ? 60  ALA H CB  1 
ATOM   430  N N   . SER A 1 61  ? 28.97305  8.28719  13.84930  1.000 49.20310  ? 61  SER H N   1 
ATOM   431  C CA  . SER A 1 61  ? 29.27082  6.94919  13.34775  1.000 56.85897  ? 61  SER H CA  1 
ATOM   432  C C   . SER A 1 61  ? 27.99778  6.15094  13.08637  1.000 59.17606  ? 61  SER H C   1 
ATOM   433  O O   . SER A 1 61  ? 27.92339  5.40554  12.10076  1.000 56.88963  ? 61  SER H O   1 
ATOM   434  C CB  . SER A 1 61  ? 30.18616  6.21554  14.32923  1.000 60.60003  ? 61  SER H CB  1 
ATOM   435  O OG  . SER A 1 61  ? 29.73105  6.35626  15.66594  1.000 70.37230  ? 61  SER H OG  1 
ATOM   436  N N   . TRP A 1 62  ? 26.97422  6.32205  13.93018  1.000 56.30349  ? 62  TRP H N   1 
ATOM   437  C CA  . TRP A 1 62  ? 25.72108  5.60384  13.72941  1.000 53.13997  ? 62  TRP H CA  1 
ATOM   438  C C   . TRP A 1 62  ? 25.05098  5.94941  12.40567  1.000 41.51481  ? 62  TRP H C   1 
ATOM   439  O O   . TRP A 1 62  ? 24.27995  5.13353  11.89056  1.000 57.47379  ? 62  TRP H O   1 
ATOM   440  C CB  . TRP A 1 62  ? 24.74730  5.87305  14.88842  1.000 54.34809  ? 62  TRP H CB  1 
ATOM   441  C CG  . TRP A 1 62  ? 24.08779  7.24151  14.88831  1.000 49.26741  ? 62  TRP H CG  1 
ATOM   442  C CD1 . TRP A 1 62  ? 24.43661  8.31774  15.65533  1.000 52.63059  ? 62  TRP H CD1 1 
ATOM   443  C CD2 . TRP A 1 62  ? 22.95880  7.66284  14.10263  1.000 47.05452  ? 62  TRP H CD2 1 
ATOM   444  N NE1 . TRP A 1 62  ? 23.59976  9.37998  15.39465  1.000 48.27285  ? 62  TRP H NE1 1 
ATOM   445  C CE2 . TRP A 1 62  ? 22.68584  9.00248  14.44579  1.000 45.45507  ? 62  TRP H CE2 1 
ATOM   446  C CE3 . TRP A 1 62  ? 22.15293  7.03816  13.14636  1.000 43.19165  ? 62  TRP H CE3 1 
ATOM   447  C CZ2 . TRP A 1 62  ? 21.64650  9.72678  13.86003  1.000 41.68673  ? 62  TRP H CZ2 1 
ATOM   448  C CZ3 . TRP A 1 62  ? 21.12281  7.76358  12.56153  1.000 38.51591  ? 62  TRP H CZ3 1 
ATOM   449  C CH2 . TRP A 1 62  ? 20.88313  9.09280  12.91921  1.000 37.15146  ? 62  TRP H CH2 1 
ATOM   450  N N   . ALA A 1 63  ? 25.31285  7.12869  11.84328  1.000 45.27038  ? 63  ALA H N   1 
ATOM   451  C CA  . ALA A 1 63  ? 24.57806  7.60157  10.67708  1.000 39.91874  ? 63  ALA H CA  1 
ATOM   452  C C   . ALA A 1 63  ? 25.39470  7.60775  9.39472   1.000 47.85921  ? 63  ALA H C   1 
ATOM   453  O O   . ALA A 1 63  ? 24.83984  7.90519  8.32802   1.000 44.49667  ? 63  ALA H O   1 
ATOM   454  C CB  . ALA A 1 63  ? 24.02995  9.01081  10.93050  1.000 48.10077  ? 63  ALA H CB  1 
ATOM   455  N N   . LYS A 1 64  ? 26.68952  7.28481  9.46066   1.000 57.29854  ? 64  LYS H N   1 
ATOM   456  C CA  . LYS A 1 64  ? 27.55118  7.45315  8.29175   1.000 54.76786  ? 64  LYS H CA  1 
ATOM   457  C C   . LYS A 1 64  ? 27.10492  6.57362  7.12615   1.000 47.89767  ? 64  LYS H C   1 
ATOM   458  O O   . LYS A 1 64  ? 27.16152  6.99622  5.96594   1.000 53.61944  ? 64  LYS H O   1 
ATOM   459  C CB  . LYS A 1 64  ? 29.00473  7.16037  8.66902   1.000 50.54513  ? 64  LYS H CB  1 
ATOM   460  C CG  . LYS A 1 64  ? 29.99987  7.51242  7.57020   1.000 58.38615  ? 64  LYS H CG  1 
ATOM   461  C CD  . LYS A 1 64  ? 31.39683  7.75257  8.11833   1.000 61.85500  ? 64  LYS H CD  1 
ATOM   462  C CE  . LYS A 1 64  ? 32.29648  8.36909  7.05485   1.000 68.38723  ? 64  LYS H CE  1 
ATOM   463  N NZ  . LYS A 1 64  ? 31.69285  9.60448  6.46701   1.000 59.21679  ? 64  LYS H NZ  1 
ATOM   464  N N   . SER A 1 65  ? 26.62900  5.35934  7.41688   1.000 51.91888  ? 65  SER H N   1 
ATOM   465  C CA  . SER A 1 65  ? 26.29496  4.41264  6.35405   1.000 58.57994  ? 65  SER H CA  1 
ATOM   466  C C   . SER A 1 65  ? 25.18802  4.93624  5.44444   1.000 56.35818  ? 65  SER H C   1 
ATOM   467  O O   . SER A 1 65  ? 25.24644  4.75759  4.22098   1.000 46.47474  ? 65  SER H O   1 
ATOM   468  C CB  . SER A 1 65  ? 25.88400  3.06737  6.95684   1.000 54.88967  ? 65  SER H CB  1 
ATOM   469  O OG  . SER A 1 65  ? 26.96691  2.45026  7.62940   1.000 66.15671  ? 65  SER H OG  1 
ATOM   470  N N   . ARG A 1 66  ? 24.17030  5.58367  6.01626   1.000 56.44166  ? 66  ARG H N   1 
ATOM   471  C CA  . ARG A 1 66  ? 22.93219  5.85193  5.29115   1.000 57.02581  ? 66  ARG H CA  1 
ATOM   472  C C   . ARG A 1 66  ? 22.68920  7.32044  4.97119   1.000 55.20423  ? 66  ARG H C   1 
ATOM   473  O O   . ARG A 1 66  ? 21.74319  7.62177  4.23189   1.000 48.39448  ? 66  ARG H O   1 
ATOM   474  C CB  . ARG A 1 66  ? 21.72866  5.31741  6.08886   1.000 55.23167  ? 66  ARG H CB  1 
ATOM   475  C CG  . ARG A 1 66  ? 21.89981  3.88996  6.58239   1.000 54.84313  ? 66  ARG H CG  1 
ATOM   476  C CD  . ARG A 1 66  ? 20.62853  3.33875  7.22418   1.000 53.09845  ? 66  ARG H CD  1 
ATOM   477  N NE  . ARG A 1 66  ? 20.39737  3.84570  8.57223   1.000 48.15427  ? 66  ARG H NE  1 
ATOM   478  C CZ  . ARG A 1 66  ? 19.26761  4.41033  8.98006   1.000 41.96010  ? 66  ARG H CZ  1 
ATOM   479  N NH1 . ARG A 1 66  ? 18.23428  4.55719  8.16563   1.000 39.23406  ? 66  ARG H NH1 1 
ATOM   480  N NH2 . ARG A 1 66  ? 19.16713  4.82553  10.24212  1.000 36.23262  ? 66  ARG H NH2 1 
ATOM   481  N N   . SER A 1 67  ? 23.50554  8.23483  5.49001   1.000 57.39709  ? 67  SER H N   1 
ATOM   482  C CA  . SER A 1 67  ? 23.18783  9.65496  5.48237   1.000 51.84631  ? 67  SER H CA  1 
ATOM   483  C C   . SER A 1 67  ? 24.11689  10.42536 4.55535   1.000 50.11407  ? 67  SER H C   1 
ATOM   484  O O   . SER A 1 67  ? 25.31403  10.13891 4.47709   1.000 48.46579  ? 67  SER H O   1 
ATOM   485  C CB  . SER A 1 67  ? 23.28406  10.23401 6.89284   1.000 51.40753  ? 67  SER H CB  1 
ATOM   486  O OG  . SER A 1 67  ? 22.53506  9.45793  7.80921   1.000 60.45651  ? 67  SER H OG  1 
ATOM   487  N N   . THR A 1 68  ? 23.55176  11.39977 3.84723   1.000 47.91069  ? 68  THR H N   1 
ATOM   488  C CA  . THR A 1 68  ? 24.32575  12.37018 3.08381   1.000 48.69728  ? 68  THR H CA  1 
ATOM   489  C C   . THR A 1 68  ? 23.72651  13.74559 3.33064   1.000 49.50046  ? 68  THR H C   1 
ATOM   490  O O   . THR A 1 68  ? 22.53001  13.94845 3.09566   1.000 48.56902  ? 68  THR H O   1 
ATOM   491  C CB  . THR A 1 68  ? 24.31949  12.05794 1.58049   1.000 56.48724  ? 68  THR H CB  1 
ATOM   492  O OG1 . THR A 1 68  ? 23.21052  12.72168 0.95514   1.000 52.41370  ? 68  THR H OG1 1 
ATOM   493  C CG2 . THR A 1 68  ? 24.21896  10.55398 1.32807   1.000 52.24469  ? 68  THR H CG2 1 
ATOM   494  N N   . ILE A 1 69  ? 24.54655  14.68933 3.79597   1.000 51.97714  ? 69  ILE H N   1 
ATOM   495  C CA  . ILE A 1 69  ? 24.12387  16.07629 3.98083   1.000 45.44798  ? 69  ILE H CA  1 
ATOM   496  C C   . ILE A 1 69  ? 24.83157  16.94401 2.95051   1.000 43.30832  ? 69  ILE H C   1 
ATOM   497  O O   . ILE A 1 69  ? 26.05022  16.83642 2.77103   1.000 43.52042  ? 69  ILE H O   1 
ATOM   498  C CB  . ILE A 1 69  ? 24.41258  16.58744 5.40132   1.000 45.59319  ? 69  ILE H CB  1 
ATOM   499  C CG1 . ILE A 1 69  ? 23.73702  15.69479 6.44443   1.000 42.95651  ? 69  ILE H CG1 1 
ATOM   500  C CG2 . ILE A 1 69  ? 23.93294  18.02993 5.53915   1.000 37.87848  ? 69  ILE H CG2 1 
ATOM   501  C CD1 . ILE A 1 69  ? 24.17420  15.98720 7.84133   1.000 41.73699  ? 69  ILE H CD1 1 
ATOM   502  N N   . THR A 1 70  ? 24.06583  17.80854 2.28687   1.000 44.07716  ? 70  THR H N   1 
ATOM   503  C CA  . THR A 1 70  ? 24.56919  18.70808 1.26125   1.000 55.28740  ? 70  THR H CA  1 
ATOM   504  C C   . THR A 1 70  ? 23.93135  20.07597 1.44952   1.000 62.48102  ? 70  THR H C   1 
ATOM   505  O O   . THR A 1 70  ? 22.97982  20.24128 2.21835   1.000 57.71371  ? 70  THR H O   1 
ATOM   506  C CB  . THR A 1 70  ? 24.25067  18.20923 -0.15543  1.000 49.46963  ? 70  THR H CB  1 
ATOM   507  O OG1 . THR A 1 70  ? 22.83776  18.30470 -0.38528  1.000 50.21073  ? 70  THR H OG1 1 
ATOM   508  C CG2 . THR A 1 70  ? 24.70740  16.77350 -0.34978  1.000 49.18497  ? 70  THR H CG2 1 
ATOM   509  N N   . ARG A 1 71  ? 24.45078  21.05912 0.71205   1.000 65.14365  ? 71  ARG H N   1 
ATOM   510  C CA  . ARG A 1 71  ? 23.83497  22.37596 0.63318   1.000 60.98757  ? 71  ARG H CA  1 
ATOM   511  C C   . ARG A 1 71  ? 23.86208  22.84960 -0.80987  1.000 55.47292  ? 71  ARG H C   1 
ATOM   512  O O   . ARG A 1 71  ? 24.75704  22.49510 -1.58274  1.000 52.56886  ? 71  ARG H O   1 
ATOM   513  C CB  . ARG A 1 71  ? 24.53749  23.40904 1.53863   1.000 60.56784  ? 71  ARG H CB  1 
ATOM   514  C CG  . ARG A 1 71  ? 25.94039  23.82243 1.09283   1.000 50.30202  ? 71  ARG H CG  1 
ATOM   515  C CD  . ARG A 1 71  ? 26.58344  24.77537 2.09880   1.000 57.52100  ? 71  ARG H CD  1 
ATOM   516  N NE  . ARG A 1 71  ? 27.99305  25.01545 1.81059   1.000 52.22154  ? 71  ARG H NE  1 
ATOM   517  C CZ  . ARG A 1 71  ? 28.85845  25.54379 2.66584   1.000 58.16099  ? 71  ARG H CZ  1 
ATOM   518  N NH1 . ARG A 1 71  ? 28.49394  25.90519 3.88632   1.000 60.57508  ? 71  ARG H NH1 1 
ATOM   519  N NH2 . ARG A 1 71  ? 30.12512  25.70296 2.29151   1.000 55.21239  ? 71  ARG H NH2 1 
ATOM   520  N N   . ASN A 1 72  ? 22.86824  23.64821 -1.17182  1.000 60.05728  ? 72  ASN H N   1 
ATOM   521  C CA  . ASN A 1 72  ? 22.85581  24.30458 -2.47218  1.000 63.51519  ? 72  ASN H CA  1 
ATOM   522  C C   . ASN A 1 72  ? 22.83079  25.81048 -2.23684  1.000 70.78411  ? 72  ASN H C   1 
ATOM   523  O O   . ASN A 1 72  ? 21.78221  26.37986 -1.91274  1.000 68.44645  ? 72  ASN H O   1 
ATOM   524  C CB  . ASN A 1 72  ? 21.68424  23.84453 -3.32537  1.000 68.49590  ? 72  ASN H CB  1 
ATOM   525  C CG  . ASN A 1 72  ? 21.97992  23.96797 -4.80556  1.000 70.49188  ? 72  ASN H CG  1 
ATOM   526  O OD1 . ASN A 1 72  ? 21.59060  24.94361 -5.44562  1.000 71.07034  ? 72  ASN H OD1 1 
ATOM   527  N ND2 . ASN A 1 72  ? 22.70952  22.99268 -5.35005  1.000 61.36053  ? 72  ASN H ND2 1 
ATOM   528  N N   . THR A 1 73  ? 24.00050  26.43938 -2.40307  1.000 70.68204  ? 73  THR H N   1 
ATOM   529  C CA  . THR A 1 73  ? 24.12540  27.88122 -2.20612  1.000 66.17173  ? 73  THR H CA  1 
ATOM   530  C C   . THR A 1 73  ? 23.16813  28.64915 -3.10758  1.000 62.76732  ? 73  THR H C   1 
ATOM   531  O O   . THR A 1 73  ? 22.58427  29.65589 -2.69156  1.000 58.93848  ? 73  THR H O   1 
ATOM   532  C CB  . THR A 1 73  ? 25.56937  28.31438 -2.46070  1.000 65.20845  ? 73  THR H CB  1 
ATOM   533  O OG1 . THR A 1 73  ? 25.92023  28.03250 -3.82341  1.000 71.02626  ? 73  THR H OG1 1 
ATOM   534  C CG2 . THR A 1 73  ? 26.52108  27.55991 -1.53205  1.000 59.02137  ? 73  THR H CG2 1 
ATOM   535  N N   . ASN A 1 74  ? 22.98771  28.18343 -4.34555  1.000 70.51199  ? 74  ASN H N   1 
ATOM   536  C CA  . ASN A 1 74  ? 22.02850  28.82253 -5.24051  1.000 76.41671  ? 74  ASN H CA  1 
ATOM   537  C C   . ASN A 1 74  ? 20.60851  28.70854 -4.69545  1.000 69.98975  ? 74  ASN H C   1 
ATOM   538  O O   . ASN A 1 74  ? 19.80831  29.64517 -4.81564  1.000 65.54413  ? 74  ASN H O   1 
ATOM   539  C CB  . ASN A 1 74  ? 22.12827  28.20189 -6.63511  1.000 77.63882  ? 74  ASN H CB  1 
ATOM   540  C CG  . ASN A 1 74  ? 21.46527  29.05214 -7.70240  1.000 76.78350  ? 74  ASN H CG  1 
ATOM   541  O OD1 . ASN A 1 74  ? 22.12033  29.86122 -8.36120  1.000 75.11940  ? 74  ASN H OD1 1 
ATOM   542  N ND2 . ASN A 1 74  ? 20.15838  28.87413 -7.87707  1.000 69.84008  ? 74  ASN H ND2 1 
ATOM   543  N N   . GLU A 1 75  ? 20.28485  27.57144 -4.07722  1.000 68.82649  ? 75  GLU H N   1 
ATOM   544  C CA  . GLU A 1 75  ? 18.95475  27.35091 -3.52575  1.000 71.91881  ? 75  GLU H CA  1 
ATOM   545  C C   . GLU A 1 75  ? 18.76045  27.98615 -2.15720  1.000 67.06550  ? 75  GLU H C   1 
ATOM   546  O O   . GLU A 1 75  ? 17.61043  28.15930 -1.73225  1.000 65.01913  ? 75  GLU H O   1 
ATOM   547  C CB  . GLU A 1 75  ? 18.67002  25.85135 -3.42254  1.000 72.40041  ? 75  GLU H CB  1 
ATOM   548  C CG  . GLU A 1 75  ? 18.52882  25.13834 -4.75527  1.000 75.06739  ? 75  GLU H CG  1 
ATOM   549  C CD  . GLU A 1 75  ? 17.24516  25.48971 -5.47983  1.000 77.43365  ? 75  GLU H CD  1 
ATOM   550  O OE1 . GLU A 1 75  ? 17.02275  26.68584 -5.78136  1.000 75.14995  ? 75  GLU H OE1 1 
ATOM   551  O OE2 . GLU A 1 75  ? 16.45330  24.55961 -5.74322  1.000 79.43089  ? 75  GLU H OE2 1 
ATOM   552  N N   . ASN A 1 76  ? 19.84982  28.33606 -1.46808  1.000 62.02557  ? 76  ASN H N   1 
ATOM   553  C CA  . ASN A 1 76  ? 19.78968  28.81525 -0.08602  1.000 65.81516  ? 76  ASN H CA  1 
ATOM   554  C C   . ASN A 1 76  ? 19.16632  27.74942 0.81665   1.000 68.00029  ? 76  ASN H C   1 
ATOM   555  O O   . ASN A 1 76  ? 18.38924  28.04992 1.72660   1.000 62.60126  ? 76  ASN H O   1 
ATOM   556  C CB  . ASN A 1 76  ? 19.03014  30.14367 0.00970   1.000 58.58511  ? 76  ASN H CB  1 
ATOM   557  C CG  . ASN A 1 76  ? 19.56973  31.05631 1.09327   1.000 52.15281  ? 76  ASN H CG  1 
ATOM   558  O OD1 . ASN A 1 76  ? 20.71185  30.92041 1.53264   1.000 62.27854  ? 76  ASN H OD1 1 
ATOM   559  N ND2 . ASN A 1 76  ? 18.74388  31.99638 1.52796   1.000 55.03874  ? 76  ASN H ND2 1 
ATOM   560  N N   . THR A 1 77  ? 19.50741  26.48595 0.55102   1.000 54.59829  ? 77  THR H N   1 
ATOM   561  C CA  . THR A 1 77  ? 18.96914  25.35254 1.28404   1.000 56.85051  ? 77  THR H CA  1 
ATOM   562  C C   . THR A 1 77  ? 20.09153  24.41807 1.71176   1.000 52.52271  ? 77  THR H C   1 
ATOM   563  O O   . THR A 1 77  ? 21.16048  24.36755 1.09376   1.000 49.00335  ? 77  THR H O   1 
ATOM   564  C CB  . THR A 1 77  ? 17.95191  24.55007 0.45383   1.000 56.26815  ? 77  THR H CB  1 
ATOM   565  O OG1 . THR A 1 77  ? 18.60232  24.00517 -0.70021  1.000 62.06468  ? 77  THR H OG1 1 
ATOM   566  C CG2 . THR A 1 77  ? 16.79195  25.42362 0.01312   1.000 58.98305  ? 77  THR H CG2 1 
ATOM   567  N N   . VAL A 1 78  ? 19.82768  23.68583 2.79104   1.000 56.08533  ? 78  VAL H N   1 
ATOM   568  C CA  . VAL A 1 78  ? 20.63899  22.56355 3.24405   1.000 55.45016  ? 78  VAL H CA  1 
ATOM   569  C C   . VAL A 1 78  ? 19.74217  21.32883 3.21102   1.000 52.42517  ? 78  VAL H C   1 
ATOM   570  O O   . VAL A 1 78  ? 18.51896  21.43957 3.34986   1.000 53.43775  ? 78  VAL H O   1 
ATOM   571  C CB  . VAL A 1 78  ? 21.22627  22.82633 4.65295   1.000 50.94655  ? 78  VAL H CB  1 
ATOM   572  C CG1 . VAL A 1 78  ? 20.11593  22.91763 5.69818   1.000 53.02170  ? 78  VAL H CG1 1 
ATOM   573  C CG2 . VAL A 1 78  ? 22.27363  21.77907 5.02658   1.000 43.29320  ? 78  VAL H CG2 1 
ATOM   574  N N   . THR A 1 79  ? 20.33849  20.15288 2.98810   1.000 43.34588  ? 79  THR H N   1 
ATOM   575  C CA  . THR A 1 79  ? 19.54275  18.96139 2.70205   1.000 40.47516  ? 79  THR H CA  1 
ATOM   576  C C   . THR A 1 79  ? 20.07183  17.73470 3.43494   1.000 47.07668  ? 79  THR H C   1 
ATOM   577  O O   . THR A 1 79  ? 21.28216  17.48608 3.44836   1.000 42.52354  ? 79  THR H O   1 
ATOM   578  C CB  . THR A 1 79  ? 19.49409  18.69647 1.18883   1.000 47.84865  ? 79  THR H CB  1 
ATOM   579  O OG1 . THR A 1 79  ? 18.59360  19.62982 0.57618   1.000 51.35677  ? 79  THR H OG1 1 
ATOM   580  C CG2 . THR A 1 79  ? 19.01696  17.27763 0.89331   1.000 49.67127  ? 79  THR H CG2 1 
ATOM   581  N N   . LEU A 1 80  ? 19.15546  16.98069 4.05310   1.000 45.98633  ? 80  LEU H N   1 
ATOM   582  C CA  . LEU A 1 80  ? 19.44669  15.67410 4.63775   1.000 46.73111  ? 80  LEU H CA  1 
ATOM   583  C C   . LEU A 1 80  ? 18.81394  14.58701 3.77770   1.000 44.20845  ? 80  LEU H C   1 
ATOM   584  O O   . LEU A 1 80  ? 17.61517  14.64189 3.47199   1.000 37.91912  ? 80  LEU H O   1 
ATOM   585  C CB  . LEU A 1 80  ? 18.92927  15.55525 6.07828   1.000 37.13591  ? 80  LEU H CB  1 
ATOM   586  C CG  . LEU A 1 80  ? 19.06107  14.15995 6.71759   1.000 32.63401  ? 80  LEU H CG  1 
ATOM   587  C CD1 . LEU A 1 80  ? 20.50813  13.71439 6.81902   1.000 29.84731  ? 80  LEU H CD1 1 
ATOM   588  C CD2 . LEU A 1 80  ? 18.39466  14.10455 8.11342   1.000 35.67142  ? 80  LEU H CD2 1 
ATOM   589  N N   . LYS A 1 81  ? 19.62728  13.61341 3.38261   1.000 43.05053  ? 81  LYS H N   1 
ATOM   590  C CA  . LYS A 1 81  ? 19.16970  12.44245 2.65562   1.000 43.43764  ? 81  LYS H CA  1 
ATOM   591  C C   . LYS A 1 81  ? 19.47959  11.21184 3.48979   1.000 33.30500  ? 81  LYS H C   1 
ATOM   592  O O   . LYS A 1 81  ? 20.62639  11.00890 3.90676   1.000 40.31853  ? 81  LYS H O   1 
ATOM   593  C CB  . LYS A 1 81  ? 19.83827  12.35058 1.28152   1.000 49.94662  ? 81  LYS H CB  1 
ATOM   594  C CG  . LYS A 1 81  ? 19.36457  11.18872 0.43146   1.000 61.85377  ? 81  LYS H CG  1 
ATOM   595  C CD  . LYS A 1 81  ? 17.86083  11.25240 0.18415   1.000 51.12479  ? 81  LYS H CD  1 
ATOM   596  C CE  . LYS A 1 81  ? 17.44993  10.23543 -0.86272  1.000 56.08995  ? 81  LYS H CE  1 
ATOM   597  N NZ  . LYS A 1 81  ? 17.97004  8.88015  -0.52655  1.000 54.01550  ? 81  LYS H NZ  1 
ATOM   598  N N   . MET A 1 82  ? 18.45588  10.40672 3.75091   1.000 35.30330  ? 82  MET H N   1 
ATOM   599  C CA  . MET A 1 82  ? 18.62936  9.18810  4.52648   1.000 39.49189  ? 82  MET H CA  1 
ATOM   600  C C   . MET A 1 82  ? 17.82610  8.08417  3.85396   1.000 45.22093  ? 82  MET H C   1 
ATOM   601  O O   . MET A 1 82  ? 16.67240  8.30213  3.46900   1.000 39.63991  ? 82  MET H O   1 
ATOM   602  C CB  . MET A 1 82  ? 18.19026  9.39155  5.98140   1.000 34.28860  ? 82  MET H CB  1 
ATOM   603  C CG  . MET A 1 82  ? 18.62960  8.26035  6.89747   1.000 52.13750  ? 82  MET H CG  1 
ATOM   604  S SD  . MET A 1 82  ? 18.27352  8.53738  8.64372   1.000 63.49626  ? 82  MET H SD  1 
ATOM   605  C CE  . MET A 1 82  ? 19.36455  9.89961  9.00468   1.000 37.99568  ? 82  MET H CE  1 
ATOM   606  N N   . ASN A 1 83  A 18.44485  6.92038  3.67925   1.000 42.37494  ? 82  ASN H N   1 
ATOM   607  C CA  . ASN A 1 83  A 17.83742  5.82059  2.93659   1.000 43.55387  ? 82  ASN H CA  1 
ATOM   608  C C   . ASN A 1 83  A 17.80441  4.57615  3.81718   1.000 40.02146  ? 82  ASN H C   1 
ATOM   609  O O   . ASN A 1 83  A 18.32854  4.56811  4.94113   1.000 37.79783  ? 82  ASN H O   1 
ATOM   610  C CB  . ASN A 1 83  A 18.57590  5.56583  1.60873   1.000 39.50258  ? 82  ASN H CB  1 
ATOM   611  C CG  . ASN A 1 83  A 20.06204  5.28976  1.79445   1.000 51.61495  ? 82  ASN H CG  1 
ATOM   612  O OD1 . ASN A 1 83  A 20.46171  4.49551  2.64962   1.000 54.16365  ? 82  ASN H OD1 1 
ATOM   613  N ND2 . ASN A 1 83  A 20.88966  5.94417  0.98466   1.000 53.77894  ? 82  ASN H ND2 1 
ATOM   614  N N   . SER A 1 84  B 17.17952  3.51889  3.28921   1.000 36.08065  ? 82  SER H N   1 
ATOM   615  C CA  . SER A 1 84  B 16.97926  2.27377  4.02986   1.000 36.53093  ? 82  SER H CA  1 
ATOM   616  C C   . SER A 1 84  B 16.29485  2.54166  5.37288   1.000 28.82418  ? 82  SER H C   1 
ATOM   617  O O   . SER A 1 84  B 16.77314  2.13996  6.43423   1.000 36.82585  ? 82  SER H O   1 
ATOM   618  C CB  . SER A 1 84  B 18.30548  1.53658  4.23907   1.000 46.40494  ? 82  SER H CB  1 
ATOM   619  O OG  . SER A 1 84  B 19.03538  1.41854  3.03044   1.000 47.96862  ? 82  SER H OG  1 
ATOM   620  N N   . LEU A 1 85  C 15.16618  3.24020  5.32291   1.000 27.29474  ? 82  LEU H N   1 
ATOM   621  C CA  . LEU A 1 85  C 14.50508  3.65587  6.55703   1.000 31.27629  ? 82  LEU H CA  1 
ATOM   622  C C   . LEU A 1 85  C 13.85080  2.47604  7.27109   1.000 27.93150  ? 82  LEU H C   1 
ATOM   623  O O   . LEU A 1 85  C 13.26550  1.59095  6.64242   1.000 27.45740  ? 82  LEU H O   1 
ATOM   624  C CB  . LEU A 1 85  C 13.46361  4.72894  6.25476   1.000 25.18532  ? 82  LEU H CB  1 
ATOM   625  C CG  . LEU A 1 85  C 14.05516  6.05177  5.76321   1.000 34.60343  ? 82  LEU H CG  1 
ATOM   626  C CD1 . LEU A 1 85  C 12.95860  7.03253  5.43631   1.000 35.34551  ? 82  LEU H CD1 1 
ATOM   627  C CD2 . LEU A 1 85  C 15.00465  6.64069  6.81207   1.000 34.61916  ? 82  LEU H CD2 1 
ATOM   628  N N   . ARG A 1 86  ? 13.96072  2.46850  8.59473   1.000 27.69804  ? 83  ARG H N   1 
ATOM   629  C CA  . ARG A 1 86  ? 13.32327  1.49019  9.46685   1.000 33.51736  ? 83  ARG H CA  1 
ATOM   630  C C   . ARG A 1 86  ? 12.39366  2.21669  10.43269  1.000 33.61927  ? 83  ARG H C   1 
ATOM   631  O O   . ARG A 1 86  ? 12.36202  3.45025  10.49061  1.000 25.09949  ? 83  ARG H O   1 
ATOM   632  C CB  . ARG A 1 86  ? 14.36455  0.67193  10.25068  1.000 36.06152  ? 83  ARG H CB  1 
ATOM   633  C CG  . ARG A 1 86  ? 15.24014  -0.23033 9.38993   1.000 42.90836  ? 83  ARG H CG  1 
ATOM   634  C CD  . ARG A 1 86  ? 16.42955  -0.79663 10.16563  1.000 47.88861  ? 83  ARG H CD  1 
ATOM   635  N NE  . ARG A 1 86  ? 17.37390  0.22989  10.60239  1.000 60.34974  ? 83  ARG H NE  1 
ATOM   636  C CZ  . ARG A 1 86  ? 18.37467  0.70287  9.86492   1.000 64.71891  ? 83  ARG H CZ  1 
ATOM   637  N NH1 . ARG A 1 86  ? 18.56650  0.30717  8.61243   1.000 54.29061  ? 83  ARG H NH1 1 
ATOM   638  N NH2 . ARG A 1 86  ? 19.20559  1.59662  10.39547  1.000 56.23101  ? 83  ARG H NH2 1 
ATOM   639  N N   . ALA A 1 87  ? 11.63340  1.44079  11.21000  1.000 26.57117  ? 84  ALA H N   1 
ATOM   640  C CA  . ALA A 1 87  ? 10.72285  2.06608  12.16981  1.000 30.64191  ? 84  ALA H CA  1 
ATOM   641  C C   . ALA A 1 87  ? 11.47731  2.92455  13.17672  1.000 26.66758  ? 84  ALA H C   1 
ATOM   642  O O   . ALA A 1 87  ? 10.97117  3.96421  13.61272  1.000 27.88875  ? 84  ALA H O   1 
ATOM   643  C CB  . ALA A 1 87  ? 9.89452   1.00490  12.88793  1.000 31.12243  ? 84  ALA H CB  1 
ATOM   644  N N   . GLU A 1 88  ? 12.69794  2.52463  13.52893  1.000 32.60515  ? 85  GLU H N   1 
ATOM   645  C CA  . GLU A 1 88  ? 13.52715  3.24731  14.48585  1.000 35.63164  ? 85  GLU H CA  1 
ATOM   646  C C   . GLU A 1 88  ? 13.94625  4.63581  13.99958  1.000 27.78363  ? 85  GLU H C   1 
ATOM   647  O O   . GLU A 1 88  ? 14.46167  5.41491  14.80345  1.000 36.59858  ? 85  GLU H O   1 
ATOM   648  C CB  . GLU A 1 88  ? 14.77484  2.41318  14.81466  1.000 42.57274  ? 85  GLU H CB  1 
ATOM   649  C CG  . GLU A 1 88  ? 14.50173  1.01032  15.39565  1.000 46.73035  ? 85  GLU H CG  1 
ATOM   650  C CD  . GLU A 1 88  ? 14.23979  -0.07018 14.33255  1.000 53.15998  ? 85  GLU H CD  1 
ATOM   651  O OE1 . GLU A 1 88  ? 13.28352  0.07237  13.54129  1.000 50.80181  ? 85  GLU H OE1 1 
ATOM   652  O OE2 . GLU A 1 88  ? 14.99412  -1.06968 14.29277  1.000 65.33266  ? 85  GLU H OE2 1 
ATOM   653  N N   . ASP A 1 89  ? 13.73805  4.97096  12.72364  1.000 26.33128  ? 86  ASP H N   1 
ATOM   654  C CA  . ASP A 1 89  ? 14.03301  6.30433  12.20986  1.000 22.37277  ? 86  ASP H CA  1 
ATOM   655  C C   . ASP A 1 89  ? 12.85677  7.26997  12.32972  1.000 25.77592  ? 86  ASP H C   1 
ATOM   656  O O   . ASP A 1 89  ? 12.98376  8.43415  11.92348  1.000 20.95672  ? 86  ASP H O   1 
ATOM   657  C CB  . ASP A 1 89  ? 14.46534  6.23004  10.73564  1.000 22.97338  ? 86  ASP H CB  1 
ATOM   658  C CG  . ASP A 1 89  ? 15.66560  5.29550  10.51378  1.000 36.38319  ? 86  ASP H CG  1 
ATOM   659  O OD1 . ASP A 1 89  ? 16.70788  5.48181  11.18220  1.000 28.48375  ? 86  ASP H OD1 1 
ATOM   660  O OD2 . ASP A 1 89  ? 15.55720  4.36978  9.67546   1.000 27.16761  ? 86  ASP H OD2 1 
ATOM   661  N N   . THR A 1 90  ? 11.71064  6.82080  12.83360  1.000 19.61577  ? 87  THR H N   1 
ATOM   662  C CA  . THR A 1 90  ? 10.61376  7.74167  13.09406  1.000 17.92009  ? 87  THR H CA  1 
ATOM   663  C C   . THR A 1 90  ? 11.05110  8.74464  14.15323  1.000 14.87933  ? 87  THR H C   1 
ATOM   664  O O   . THR A 1 90  ? 11.49767  8.35705  15.23585  1.000 17.32590  ? 87  THR H O   1 
ATOM   665  C CB  . THR A 1 90  ? 9.37202   6.97976  13.58266  1.000 20.52959  ? 87  THR H CB  1 
ATOM   666  O OG1 . THR A 1 90  ? 8.87325   6.12767  12.54306  1.000 15.72122  ? 87  THR H OG1 1 
ATOM   667  C CG2 . THR A 1 90  ? 8.28152   7.95567  14.00850  1.000 20.24551  ? 87  THR H CG2 1 
ATOM   668  N N   . ALA A 1 91  ? 10.90597  10.03291 13.84942  1.000 21.15618  ? 88  ALA H N   1 
ATOM   669  C CA  . ALA A 1 91  ? 11.42492  11.07484 14.73137  1.000 22.31549  ? 88  ALA H CA  1 
ATOM   670  C C   . ALA A 1 91  ? 11.01067  12.43085 14.18373  1.000 22.16670  ? 88  ALA H C   1 
ATOM   671  O O   . ALA A 1 91  ? 10.65339  12.56335 13.00930  1.000 18.37266  ? 88  ALA H O   1 
ATOM   672  C CB  . ALA A 1 91  ? 12.95946  11.01212 14.86063  1.000 16.67158  ? 88  ALA H CB  1 
ATOM   673  N N   . VAL A 1 92  ? 11.06729  13.43843 15.05282  1.000 19.58767  ? 89  VAL H N   1 
ATOM   674  C CA  . VAL A 1 92  ? 11.05563  14.82921 14.60282  1.000 22.67266  ? 89  VAL H CA  1 
ATOM   675  C C   . VAL A 1 92  ? 12.47211  15.22685 14.20460  1.000 21.89516  ? 89  VAL H C   1 
ATOM   676  O O   . VAL A 1 92  ? 13.41308  15.11818 15.00237  1.000 22.33681  ? 89  VAL H O   1 
ATOM   677  C CB  . VAL A 1 92  ? 10.51054  15.75900 15.69961  1.000 24.41544  ? 89  VAL H CB  1 
ATOM   678  C CG1 . VAL A 1 92  ? 10.50406  17.22299 15.19423  1.000 22.59936  ? 89  VAL H CG1 1 
ATOM   679  C CG2 . VAL A 1 92  ? 9.11389   15.33461 16.10644  1.000 22.56956  ? 89  VAL H CG2 1 
ATOM   680  N N   . TYR A 1 93  ? 12.62336  15.70700 12.97924  1.000 22.77796  ? 90  TYR H N   1 
ATOM   681  C CA  . TYR A 1 93  ? 13.92077  16.03824 12.41064  1.000 28.55821  ? 90  TYR H CA  1 
ATOM   682  C C   . TYR A 1 93  ? 14.06690  17.55109 12.38225  1.000 27.53194  ? 90  TYR H C   1 
ATOM   683  O O   . TYR A 1 93  ? 13.13317  18.25164 11.98647  1.000 26.53415  ? 90  TYR H O   1 
ATOM   684  C CB  . TYR A 1 93  ? 14.06143  15.46294 10.99866  1.000 24.00379  ? 90  TYR H CB  1 
ATOM   685  C CG  . TYR A 1 93  ? 14.32920  13.97382 10.99615  1.000 27.28592  ? 90  TYR H CG  1 
ATOM   686  C CD1 . TYR A 1 93  ? 13.30590  13.06163 11.22237  1.000 28.38559  ? 90  TYR H CD1 1 
ATOM   687  C CD2 . TYR A 1 93  ? 15.61180  13.48381 10.78634  1.000 22.97767  ? 90  TYR H CD2 1 
ATOM   688  C CE1 . TYR A 1 93  ? 13.56298  11.69700 11.24485  1.000 25.17425  ? 90  TYR H CE1 1 
ATOM   689  C CE2 . TYR A 1 93  ? 15.87295  12.13385 10.80047  1.000 29.19366  ? 90  TYR H CE2 1 
ATOM   690  C CZ  . TYR A 1 93  ? 14.84126  11.24462 11.04157  1.000 26.02629  ? 90  TYR H CZ  1 
ATOM   691  O OH  . TYR A 1 93  ? 15.10582  9.90187  11.06087  1.000 23.47154  ? 90  TYR H OH  1 
ATOM   692  N N   . TYR A 1 94  ? 15.23189  18.04489 12.80328  1.000 25.66398  ? 91  TYR H N   1 
ATOM   693  C CA  . TYR A 1 94  ? 15.49968  19.47795 12.86461  1.000 27.56155  ? 91  TYR H CA  1 
ATOM   694  C C   . TYR A 1 94  ? 16.78862  19.80873 12.12140  1.000 22.44623  ? 91  TYR H C   1 
ATOM   695  O O   . TYR A 1 94  ? 17.77957  19.07597 12.21702  1.000 28.23915  ? 91  TYR H O   1 
ATOM   696  C CB  . TYR A 1 94  ? 15.66918  19.98866 14.31486  1.000 27.02854  ? 91  TYR H CB  1 
ATOM   697  C CG  . TYR A 1 94  ? 14.53318  19.79618 15.30242  1.000 24.96931  ? 91  TYR H CG  1 
ATOM   698  C CD1 . TYR A 1 94  ? 13.54600  20.76377 15.46042  1.000 25.09323  ? 91  TYR H CD1 1 
ATOM   699  C CD2 . TYR A 1 94  ? 14.49461  18.68476 16.13326  1.000 20.98002  ? 91  TYR H CD2 1 
ATOM   700  C CE1 . TYR A 1 94  ? 12.52290  20.60881 16.39703  1.000 24.87517  ? 91  TYR H CE1 1 
ATOM   701  C CE2 . TYR A 1 94  ? 13.47833  18.52116 17.06037  1.000 22.97468  ? 91  TYR H CE2 1 
ATOM   702  C CZ  . TYR A 1 94  ? 12.49615  19.48290 17.19383  1.000 25.45281  ? 91  TYR H CZ  1 
ATOM   703  O OH  . TYR A 1 94  ? 11.49049  19.30776 18.12937  1.000 25.01384  ? 91  TYR H OH  1 
ATOM   704  N N   . CYS A 1 95  ? 16.79062  20.93892 11.42793  1.000 27.89261  ? 92  CYS H N   1 
ATOM   705  C CA  . CYS A 1 95  ? 18.02567  21.56360 10.96707  0.850 32.42936  ? 92  CYS H CA  1 
ATOM   706  C C   . CYS A 1 95  ? 18.32736  22.74626 11.88164  1.000 20.10351  ? 92  CYS H C   1 
ATOM   707  O O   . CYS A 1 95  ? 17.42673  23.53213 12.19581  1.000 30.01892  ? 92  CYS H O   1 
ATOM   708  C CB  . CYS A 1 95  ? 17.88419  22.03042 9.51680   1.000 27.27436  ? 92  CYS H CB  1 
ATOM   709  S SG  . CYS A 1 95  ? 16.60313  23.26205 9.37616   0.579 36.19128  ? 92  CYS H SG  1 
ATOM   710  N N   . ALA A 1 96  ? 19.58052  22.87519 12.30936  1.000 29.48979  ? 93  ALA H N   1 
ATOM   711  C CA  . ALA A 1 96  ? 19.88630  23.95040 13.23981  1.000 36.20494  ? 93  ALA H CA  1 
ATOM   712  C C   . ALA A 1 96  ? 21.37126  24.26431 13.25076  1.000 31.35990  ? 93  ALA H C   1 
ATOM   713  O O   . ALA A 1 96  ? 22.20355  23.35656 13.25423  1.000 33.37233  ? 93  ALA H O   1 
ATOM   714  C CB  . ALA A 1 96  ? 19.43914  23.59366 14.66419  1.000 32.61822  ? 93  ALA H CB  1 
ATOM   715  N N   . LYS A 1 97  ? 21.68906  25.55841 13.30379  1.000 34.73679  ? 94  LYS H N   1 
ATOM   716  C CA  . LYS A 1 97  ? 22.99800  25.99875 13.77303  1.000 28.05769  ? 94  LYS H CA  1 
ATOM   717  C C   . LYS A 1 97  ? 22.95589  25.97751 15.29499  1.000 27.02244  ? 94  LYS H C   1 
ATOM   718  O O   . LYS A 1 97  ? 22.21990  26.75453 15.90959  1.000 28.17758  ? 94  LYS H O   1 
ATOM   719  C CB  . LYS A 1 97  ? 23.33328  27.39311 13.24483  1.000 35.96332  ? 94  LYS H CB  1 
ATOM   720  C CG  . LYS A 1 97  ? 24.60845  27.97314 13.84889  1.000 34.99933  ? 94  LYS H CG  1 
ATOM   721  C CD  . LYS A 1 97  ? 24.82962  29.44118 13.46042  1.000 40.48068  ? 94  LYS H CD  1 
ATOM   722  C CE  . LYS A 1 97  ? 25.85561  30.09517 14.37903  1.000 32.99721  ? 94  LYS H CE  1 
ATOM   723  N NZ  . LYS A 1 97  ? 26.92195  29.15265 14.80901  1.000 42.47784  ? 94  LYS H NZ  1 
ATOM   724  N N   . LEU A 1 98  ? 23.72750  25.07731 15.90536  1.000 32.21542  ? 95  LEU H N   1 
ATOM   725  C CA  . LEU A 1 98  ? 23.48473  24.74359 17.30383  1.000 30.28895  ? 95  LEU H CA  1 
ATOM   726  C C   . LEU A 1 98  ? 23.96202  25.83264 18.26240  1.000 40.63756  ? 95  LEU H C   1 
ATOM   727  O O   . LEU A 1 98  ? 23.47549  25.89351 19.39932  1.000 30.61189  ? 95  LEU H O   1 
ATOM   728  C CB  . LEU A 1 98  ? 24.14503  23.40816 17.63498  1.000 31.13386  ? 95  LEU H CB  1 
ATOM   729  C CG  . LEU A 1 98  ? 23.40025  22.19774 17.04855  1.000 35.70904  ? 95  LEU H CG  1 
ATOM   730  C CD1 . LEU A 1 98  ? 24.14471  20.90797 17.32452  1.000 32.25589  ? 95  LEU H CD1 1 
ATOM   731  C CD2 . LEU A 1 98  ? 21.99818  22.12667 17.63032  1.000 33.32280  ? 95  LEU H CD2 1 
ATOM   732  N N   . GLY A 1 99  ? 24.89508  26.68861 17.83281  1.000 40.15249  ? 96  GLY H N   1 
ATOM   733  C CA  . GLY A 1 99  ? 25.39774  27.75974 18.67314  1.000 30.91891  ? 96  GLY H CA  1 
ATOM   734  C C   . GLY A 1 99  ? 25.99900  27.26768 19.96787  1.000 32.74303  ? 96  GLY H C   1 
ATOM   735  O O   . GLY A 1 99  ? 25.69785  27.78646 21.04969  1.000 39.32545  ? 96  GLY H O   1 
ATOM   736  N N   . SER A 1 100 ? 26.84648  26.24873 19.87440  1.000 29.53621  ? 97  SER H N   1 
ATOM   737  C CA  . SER A 1 100 ? 27.54548  25.78421 21.06195  1.000 37.61410  ? 97  SER H CA  1 
ATOM   738  C C   . SER A 1 100 ? 28.53657  26.81364 21.58441  1.000 37.06250  ? 97  SER H C   1 
ATOM   739  O O   . SER A 1 100 ? 28.91137  26.74366 22.75651  1.000 35.97194  ? 97  SER H O   1 
ATOM   740  C CB  . SER A 1 100 ? 28.28746  24.48386 20.76526  1.000 36.80351  ? 97  SER H CB  1 
ATOM   741  O OG  . SER A 1 100 ? 29.28908  24.71269 19.78557  1.000 42.69226  ? 97  SER H OG  1 
ATOM   742  N N   . GLY A 1 101 ? 28.98113  27.74956 20.74342  1.000 42.98231  ? 98  GLY H N   1 
ATOM   743  C CA  . GLY A 1 101 ? 30.04076  28.66506 21.14163  1.000 40.24110  ? 98  GLY H CA  1 
ATOM   744  C C   . GLY A 1 101 ? 29.92058  30.07845 20.61145  1.000 33.87178  ? 98  GLY H C   1 
ATOM   745  O O   . GLY A 1 101 ? 30.73335  30.93772 20.96073  1.000 45.11404  ? 98  GLY H O   1 
ATOM   746  N N   . ASN A 1 102 ? 28.91910  30.33256 19.77658  1.000 35.36058  ? 99  ASN H N   1 
ATOM   747  C CA  . ASN A 1 102 ? 28.67759  31.60725 19.12159  1.000 41.86759  ? 99  ASN H CA  1 
ATOM   748  C C   . ASN A 1 102 ? 27.31829  32.15381 19.53747  1.000 45.31681  ? 99  ASN H C   1 
ATOM   749  O O   . ASN A 1 102 ? 26.42672  31.38930 19.92292  1.000 43.30969  ? 99  ASN H O   1 
ATOM   750  C CB  . ASN A 1 102 ? 28.71982  31.46615 17.58949  1.000 38.58323  ? 99  ASN H CB  1 
ATOM   751  C CG  . ASN A 1 102 ? 30.07140  30.98114 17.07521  1.000 58.84843  ? 99  ASN H CG  1 
ATOM   752  O OD1 . ASN A 1 102 ? 30.13971  30.15946 16.14900  1.000 54.21167  ? 99  ASN H OD1 1 
ATOM   753  N ND2 . ASN A 1 102 ? 31.15522  31.49507 17.66521  1.000 54.16731  ? 99  ASN H ND2 1 
ATOM   754  N N   . PRO A 1 103 ? 27.12048  33.47517 19.47004  1.000 47.45582  ? 100 PRO H N   1 
ATOM   755  C CA  . PRO A 1 103 ? 25.81649  34.04059 19.85939  1.000 40.75218  ? 100 PRO H CA  1 
ATOM   756  C C   . PRO A 1 103 ? 24.69215  33.71108 18.89540  1.000 40.05871  ? 100 PRO H C   1 
ATOM   757  O O   . PRO A 1 103 ? 23.51773  33.85246 19.26005  1.000 38.05666  ? 100 PRO H O   1 
ATOM   758  C CB  . PRO A 1 103 ? 26.08791  35.55109 19.90003  1.000 45.89041  ? 100 PRO H CB  1 
ATOM   759  C CG  . PRO A 1 103 ? 27.24735  35.74349 18.97429  1.000 44.62096  ? 100 PRO H CG  1 
ATOM   760  C CD  . PRO A 1 103 ? 28.10772  34.52855 19.17871  1.000 47.45635  ? 100 PRO H CD  1 
ATOM   761  N N   . VAL A 1 104 A 25.00095  33.28618 17.68487  1.000 36.24426  ? 100 VAL H N   1 
ATOM   762  C CA  . VAL A 1 104 A 23.97530  32.95260 16.71061  1.000 33.66832  ? 100 VAL H CA  1 
ATOM   763  C C   . VAL A 1 104 A 23.56414  31.49785 16.90022  1.000 32.88216  ? 100 VAL H C   1 
ATOM   764  O O   . VAL A 1 104 A 24.41325  30.60602 17.02262  1.000 34.35325  ? 100 VAL H O   1 
ATOM   765  C CB  . VAL A 1 104 A 24.47418  33.20700 15.28070  1.000 45.51743  ? 100 VAL H CB  1 
ATOM   766  C CG1 . VAL A 1 104 A 23.31709  33.12134 14.30178  1.000 37.96417  ? 100 VAL H CG1 1 
ATOM   767  C CG2 . VAL A 1 104 A 25.17373  34.56346 15.20256  1.000 48.86182  ? 100 VAL H CG2 1 
ATOM   768  N N   . ALA A 1 105 ? 22.25720  31.27054 16.95703  1.000 42.16204  ? 101 ALA H N   1 
ATOM   769  C CA  . ALA A 1 105 ? 21.66647  29.94016 16.97978  1.000 33.82559  ? 101 ALA H CA  1 
ATOM   770  C C   . ALA A 1 105 ? 20.31878  30.05574 16.29304  1.000 33.76602  ? 101 ALA H C   1 
ATOM   771  O O   . ALA A 1 105 ? 19.55416  30.98622 16.57235  1.000 29.44807  ? 101 ALA H O   1 
ATOM   772  C CB  . ALA A 1 105 ? 21.50792  29.40238 18.40973  1.000 33.31183  ? 101 ALA H CB  1 
ATOM   773  N N   . ILE A 1 106 ? 20.02818  29.11802 15.39648  1.000 29.87332  ? 102 ILE H N   1 
ATOM   774  C CA  . ILE A 1 106 ? 18.82215  29.18829 14.58441  1.000 34.95624  ? 102 ILE H CA  1 
ATOM   775  C C   . ILE A 1 106 ? 18.32277  27.76691 14.36017  1.000 36.40473  ? 102 ILE H C   1 
ATOM   776  O O   . ILE A 1 106 ? 19.10523  26.88142 14.00235  1.000 37.08882  ? 102 ILE H O   1 
ATOM   777  C CB  . ILE A 1 106 ? 19.10804  29.91903 13.25277  1.000 39.41111  ? 102 ILE H CB  1 
ATOM   778  C CG1 . ILE A 1 106 ? 17.94496  29.78026 12.27829  1.000 40.71991  ? 102 ILE H CG1 1 
ATOM   779  C CG2 . ILE A 1 106 ? 20.41972  29.43417 12.65684  1.000 40.55397  ? 102 ILE H CG2 1 
ATOM   780  C CD1 . ILE A 1 106 ? 16.72866  30.59033 12.66541  1.000 55.72147  ? 102 ILE H CD1 1 
ATOM   781  N N   . TRP A 1 107 ? 17.03197  27.54400 14.59391  1.000 35.89676  ? 103 TRP H N   1 
ATOM   782  C CA  . TRP A 1 107 ? 16.43611  26.22059 14.50917  1.000 36.93480  ? 103 TRP H CA  1 
ATOM   783  C C   . TRP A 1 107 ? 15.20969  26.28065 13.62073  1.000 36.57987  ? 103 TRP H C   1 
ATOM   784  O O   . TRP A 1 107 ? 14.38269  27.18660 13.75865  1.000 32.05285  ? 103 TRP H O   1 
ATOM   785  C CB  . TRP A 1 107 ? 16.01378  25.67840 15.90588  1.000 30.18547  ? 103 TRP H CB  1 
ATOM   786  C CG  . TRP A 1 107 ? 17.11676  25.03819 16.73087  1.000 25.96615  ? 103 TRP H CG  1 
ATOM   787  C CD1 . TRP A 1 107 ? 18.24889  25.64227 17.19401  1.000 26.83609  ? 103 TRP H CD1 1 
ATOM   788  C CD2 . TRP A 1 107 ? 17.16196  23.68209 17.21894  1.000 28.13013  ? 103 TRP H CD2 1 
ATOM   789  N NE1 . TRP A 1 107 ? 19.00951  24.74630 17.90883  1.000 30.10170  ? 103 TRP H NE1 1 
ATOM   790  C CE2 . TRP A 1 107 ? 18.35868  23.54044 17.94871  1.000 25.07103  ? 103 TRP H CE2 1 
ATOM   791  C CE3 . TRP A 1 107 ? 16.31510  22.57500 17.09216  1.000 23.51986  ? 103 TRP H CE3 1 
ATOM   792  C CZ2 . TRP A 1 107 ? 18.72412  22.34440 18.56651  1.000 25.68568  ? 103 TRP H CZ2 1 
ATOM   793  C CZ3 . TRP A 1 107 ? 16.68537  21.38396 17.70053  1.000 22.07335  ? 103 TRP H CZ3 1 
ATOM   794  C CH2 . TRP A 1 107 ? 17.87861  21.27740 18.42449  1.000 27.22737  ? 103 TRP H CH2 1 
ATOM   795  N N   . GLY A 1 108 ? 15.08473  25.30280 12.72319  1.000 41.54928  ? 104 GLY H N   1 
ATOM   796  C CA  . GLY A 1 108 ? 13.81019  25.05611 12.08418  1.000 33.31430  ? 104 GLY H CA  1 
ATOM   797  C C   . GLY A 1 108 ? 12.76846  24.61544 13.09532  1.000 39.83272  ? 104 GLY H C   1 
ATOM   798  O O   . GLY A 1 108 ? 13.07230  24.30236 14.24458  1.000 37.40402  ? 104 GLY H O   1 
ATOM   799  N N   . GLN A 1 109 ? 11.50530  24.58581 12.66136  1.000 33.34019  ? 105 GLN H N   1 
ATOM   800  C CA  . GLN A 1 109 ? 10.43683  24.18676 13.57098  1.000 35.23747  ? 105 GLN H CA  1 
ATOM   801  C C   . GLN A 1 109 ? 10.34664  22.67553 13.74828  1.000 37.60775  ? 105 GLN H C   1 
ATOM   802  O O   . GLN A 1 109 ? 9.62451   22.21262 14.63947  1.000 32.56344  ? 105 GLN H O   1 
ATOM   803  C CB  . GLN A 1 109 ? 9.08627   24.73412 13.09193  1.000 42.87276  ? 105 GLN H CB  1 
ATOM   804  C CG  . GLN A 1 109 ? 8.40125   23.93696 11.96114  1.000 52.61501  ? 105 GLN H CG  1 
ATOM   805  C CD  . GLN A 1 109 ? 9.04363   24.12640 10.59145  1.000 55.44849  ? 105 GLN H CD  1 
ATOM   806  O OE1 . GLN A 1 109 ? 9.93454   24.95862 10.41359  1.000 63.26385  ? 105 GLN H OE1 1 
ATOM   807  N NE2 . GLN A 1 109 ? 8.58638   23.34847 9.61335   1.000 62.54146  ? 105 GLN H NE2 1 
ATOM   808  N N   . GLY A 1 110 ? 11.08070  21.90665 12.94807  1.000 38.66067  ? 106 GLY H N   1 
ATOM   809  C CA  . GLY A 1 110 ? 11.04169  20.46214 13.01792  1.000 37.84602  ? 106 GLY H CA  1 
ATOM   810  C C   . GLY A 1 110 ? 9.88123   19.88259 12.23603  1.000 38.99409  ? 106 GLY H C   1 
ATOM   811  O O   . GLY A 1 110 ? 8.79139   20.46404 12.20762  1.000 40.55988  ? 106 GLY H O   1 
ATOM   812  N N   . THR A 1 111 ? 10.09484  18.73805 11.59697  1.000 34.53520  ? 107 THR H N   1 
ATOM   813  C CA  . THR A 1 111 ? 9.00891   18.01253 10.95783  1.000 34.31714  ? 107 THR H CA  1 
ATOM   814  C C   . THR A 1 111 ? 9.08694   16.55257 11.35330  1.000 28.08761  ? 107 THR H C   1 
ATOM   815  O O   . THR A 1 111 ? 10.17190  15.95651 11.37759  1.000 25.73797  ? 107 THR H O   1 
ATOM   816  C CB  . THR A 1 111 ? 9.03713   18.12310 9.42519   1.000 36.25998  ? 107 THR H CB  1 
ATOM   817  O OG1 . THR A 1 111 ? 10.34705  17.80402 8.94449   1.000 43.47586  ? 107 THR H OG1 1 
ATOM   818  C CG2 . THR A 1 111 ? 8.64471   19.53197 8.97956   1.000 55.66692  ? 107 THR H CG2 1 
ATOM   819  N N   . LEU A 1 112 ? 7.92515   15.98462 11.63689  1.000 29.12166  ? 108 LEU H N   1 
ATOM   820  C CA  . LEU A 1 112 ? 7.82882   14.58121 11.98637  1.000 29.63047  ? 108 LEU H CA  1 
ATOM   821  C C   . LEU A 1 112 ? 7.96587   13.71641 10.73729  1.000 26.18272  ? 108 LEU H C   1 
ATOM   822  O O   . LEU A 1 112 ? 7.33565   13.97116 9.70766   1.000 32.67075  ? 108 LEU H O   1 
ATOM   823  C CB  . LEU A 1 112 ? 6.50457   14.29848 12.68625  1.000 23.61690  ? 108 LEU H CB  1 
ATOM   824  C CG  . LEU A 1 112 ? 6.32593   12.84670 13.12608  1.000 26.92359  ? 108 LEU H CG  1 
ATOM   825  C CD1 . LEU A 1 112 ? 7.31260   12.48071 14.24855  1.000 28.20099  ? 108 LEU H CD1 1 
ATOM   826  C CD2 . LEU A 1 112 ? 4.88672   12.55910 13.53179  1.000 25.94346  ? 108 LEU H CD2 1 
ATOM   827  N N   . VAL A 1 113 ? 8.80515   12.69994 10.82469  1.000 25.44255  ? 109 VAL H N   1 
ATOM   828  C CA  . VAL A 1 113 ? 8.89004   11.67502 9.79694   1.000 24.20666  ? 109 VAL H CA  1 
ATOM   829  C C   . VAL A 1 113 ? 8.42831   10.38173 10.44614  1.000 24.19737  ? 109 VAL H C   1 
ATOM   830  O O   . VAL A 1 113 ? 9.02359   9.93628  11.43145  1.000 21.10014  ? 109 VAL H O   1 
ATOM   831  C CB  . VAL A 1 113 ? 10.31380  11.55182 9.23515   1.000 28.92279  ? 109 VAL H CB  1 
ATOM   832  C CG1 . VAL A 1 113 ? 10.39132  10.41996 8.21615   1.000 32.02593  ? 109 VAL H CG1 1 
ATOM   833  C CG2 . VAL A 1 113 ? 10.75403  12.87943 8.61379   1.000 26.98185  ? 109 VAL H CG2 1 
ATOM   834  N N   . THR A 1 114 ? 7.35858   9.79683  9.91819   1.000 19.49945  ? 110 THR H N   1 
ATOM   835  C CA  . THR A 1 114 ? 6.81581   8.54047  10.41965  1.000 17.40123  ? 110 THR H CA  1 
ATOM   836  C C   . THR A 1 114 ? 7.11666   7.44754  9.40439   1.000 20.64532  ? 110 THR H C   1 
ATOM   837  O O   . THR A 1 114 ? 6.67208   7.52873  8.25493   1.000 19.36418  ? 110 THR H O   1 
ATOM   838  C CB  . THR A 1 114 ? 5.30810   8.64812  10.65276  1.000 19.04707  ? 110 THR H CB  1 
ATOM   839  O OG1 . THR A 1 114 ? 5.04489   9.71628  11.57382  1.000 26.30088  ? 110 THR H OG1 1 
ATOM   840  C CG2 . THR A 1 114 ? 4.77714   7.34406  11.24536  1.000 21.98517  ? 110 THR H CG2 1 
ATOM   841  N N   . VAL A 1 115 ? 7.88153   6.44330  9.81581   1.000 16.88563  ? 111 VAL H N   1 
ATOM   842  C CA  . VAL A 1 115 ? 8.26600   5.34757  8.93115   1.000 17.80913  ? 111 VAL H CA  1 
ATOM   843  C C   . VAL A 1 115 ? 7.27854   4.21441  9.17545   1.000 21.55133  ? 111 VAL H C   1 
ATOM   844  O O   . VAL A 1 115 ? 7.32211   3.55550  10.21838  1.000 17.58715  ? 111 VAL H O   1 
ATOM   845  C CB  . VAL A 1 115 ? 9.71165   4.90040  9.17994   1.000 21.22462  ? 111 VAL H CB  1 
ATOM   846  C CG1 . VAL A 1 115 ? 10.12934  3.82733  8.15473   1.000 19.67531  ? 111 VAL H CG1 1 
ATOM   847  C CG2 . VAL A 1 115 ? 10.63598  6.09936  9.11930   1.000 26.89097  ? 111 VAL H CG2 1 
ATOM   848  N N   . SER A 1 116 ? 6.36778   4.00264  8.23285   1.000 22.88960  ? 112 SER H N   1 
ATOM   849  C CA  . SER A 1 116 ? 5.32810   3.00248  8.42410   1.000 20.49025  ? 112 SER H CA  1 
ATOM   850  C C   . SER A 1 116 ? 4.73811   2.64153  7.07329   1.000 19.78020  ? 112 SER H C   1 
ATOM   851  O O   . SER A 1 116 ? 4.66662   3.47965  6.17566   1.000 25.12969  ? 112 SER H O   1 
ATOM   852  C CB  . SER A 1 116 ? 4.22734   3.52497  9.35587   1.000 29.19712  ? 112 SER H CB  1 
ATOM   853  O OG  . SER A 1 116 ? 3.08859   2.68267  9.34055   1.000 22.58415  ? 112 SER H OG  1 
ATOM   854  N N   . SER A 1 117 ? 4.30159   1.38920  6.94253   1.000 21.58963  ? 113 SER H N   1 
ATOM   855  C CA  . SER A 1 117 ? 3.63109   0.94752  5.72592   1.000 22.87864  ? 113 SER H CA  1 
ATOM   856  C C   . SER A 1 117 ? 2.12696   1.21074  5.75172   1.000 20.79945  ? 113 SER H C   1 
ATOM   857  O O   . SER A 1 117 ? 1.45362   1.00833  4.73388   1.000 23.58573  ? 113 SER H O   1 
ATOM   858  C CB  . SER A 1 117 ? 3.88807   -0.55438 5.50338   1.000 20.24510  ? 113 SER H CB  1 
ATOM   859  O OG  . SER A 1 117 ? 3.46408   -1.28862 6.63932   1.000 21.79669  ? 113 SER H OG  1 
ATOM   860  N N   . ALA A 1 118 ? 1.58760   1.65307  6.88326   1.000 17.86444  ? 114 ALA H N   1 
ATOM   861  C CA  . ALA A 1 118 ? 0.16658   1.93304  6.99612   1.000 16.37958  ? 114 ALA H CA  1 
ATOM   862  C C   . ALA A 1 118 ? -0.19540  3.19771  6.21319   1.000 22.26074  ? 114 ALA H C   1 
ATOM   863  O O   . ALA A 1 118 ? 0.63677   4.07502  5.99232   1.000 22.73743  ? 114 ALA H O   1 
ATOM   864  C CB  . ALA A 1 118 ? -0.22180  2.08001  8.47657   1.000 16.68932  ? 114 ALA H CB  1 
ATOM   865  N N   . SER A 1 119 ? -1.46380  3.28986  5.81137   1.000 20.15807  ? 115 SER H N   1 
ATOM   866  C CA  . SER A 1 119 ? -1.98060  4.41406  5.04129   1.000 24.25630  ? 115 SER H CA  1 
ATOM   867  C C   . SER A 1 119 ? -2.49617  5.52075  5.95746   1.000 21.29493  ? 115 SER H C   1 
ATOM   868  O O   . SER A 1 119 ? -2.80275  5.30079  7.12586   1.000 21.94638  ? 115 SER H O   1 
ATOM   869  C CB  . SER A 1 119 ? -3.11505  3.96393  4.11681   1.000 24.62067  ? 115 SER H CB  1 
ATOM   870  O OG  . SER A 1 119 ? -2.65415  3.05453  3.13751   1.000 33.24489  ? 115 SER H OG  1 
ATOM   871  N N   . THR A 1 120 ? -2.61217  6.71795  5.39265   1.000 22.02613  ? 116 THR H N   1 
ATOM   872  C CA  . THR A 1 120 ? -3.14117  7.86794  6.11323   1.000 22.76594  ? 116 THR H CA  1 
ATOM   873  C C   . THR A 1 120 ? -4.64322  7.71571  6.35565   1.000 26.54878  ? 116 THR H C   1 
ATOM   874  O O   . THR A 1 120 ? -5.38009  7.20088  5.51059   1.000 23.15007  ? 116 THR H O   1 
ATOM   875  C CB  . THR A 1 120 ? -2.83722  9.13978  5.31602   1.000 25.73025  ? 116 THR H CB  1 
ATOM   876  O OG1 . THR A 1 120 ? -1.41555  9.28194  5.18268   1.000 28.93129  ? 116 THR H OG1 1 
ATOM   877  C CG2 . THR A 1 120 ? -3.37100  10.35749 6.01668   1.000 25.57217  ? 116 THR H CG2 1 
ATOM   878  N N   . LYS A 1 121 ? -5.10088  8.14106  7.53120   1.000 21.77237  ? 117 LYS H N   1 
ATOM   879  C CA  . LYS A 1 121 ? -6.52069  8.08477  7.87709   1.000 17.00844  ? 117 LYS H CA  1 
ATOM   880  C C   . LYS A 1 121 ? -6.88528  9.32068  8.69302   1.000 24.09225  ? 117 LYS H C   1 
ATOM   881  O O   . LYS A 1 121 ? -6.24996  9.58804  9.71434   1.000 19.65580  ? 117 LYS H O   1 
ATOM   882  C CB  . LYS A 1 121 ? -6.85034  6.82190  8.68380   1.000 20.93939  ? 117 LYS H CB  1 
ATOM   883  C CG  . LYS A 1 121 ? -8.33462  6.67186  8.99202   1.000 20.49122  ? 117 LYS H CG  1 
ATOM   884  C CD  . LYS A 1 121 ? -8.60955  5.40225  9.75039   1.000 24.68266  ? 117 LYS H CD  1 
ATOM   885  C CE  . LYS A 1 121 ? -10.08620 5.21044  9.93870   1.000 32.89038  ? 117 LYS H CE  1 
ATOM   886  N NZ  . LYS A 1 121 ? -10.62984 6.35992  10.69956  1.000 36.65540  ? 117 LYS H NZ  1 
ATOM   887  N N   . GLY A 1 122 ? -7.90626  10.06410 8.25367   1.000 17.63183  ? 118 GLY H N   1 
ATOM   888  C CA  . GLY A 1 122 ? -8.37867  11.22813 8.98214   1.000 21.32423  ? 118 GLY H CA  1 
ATOM   889  C C   . GLY A 1 122 ? -9.13505  10.85501 10.24929  1.000 17.30927  ? 118 GLY H C   1 
ATOM   890  O O   . GLY A 1 122 ? -9.65542  9.74569  10.37557  1.000 22.49713  ? 118 GLY H O   1 
ATOM   891  N N   . PRO A 1 123 ? -9.20116  11.77237 11.21511  1.000 20.40789  ? 119 PRO H N   1 
ATOM   892  C CA  . PRO A 1 123 ? -9.89709  11.48739 12.47501  1.000 18.02790  ? 119 PRO H CA  1 
ATOM   893  C C   . PRO A 1 123 ? -11.40947 11.63318 12.37575  1.000 22.00355  ? 119 PRO H C   1 
ATOM   894  O O   . PRO A 1 123 ? -11.95330 12.37067 11.55160  1.000 21.28481  ? 119 PRO H O   1 
ATOM   895  C CB  . PRO A 1 123 ? -9.33930  12.54500 13.43067  1.000 18.97739  ? 119 PRO H CB  1 
ATOM   896  C CG  . PRO A 1 123 ? -9.10260  13.72014 12.53403  1.000 24.11597  ? 119 PRO H CG  1 
ATOM   897  C CD  . PRO A 1 123 ? -8.63684  13.13276 11.19470  1.000 22.18368  ? 119 PRO H CD  1 
ATOM   898  N N   . SER A 1 124 ? -12.08195 10.90510 13.25183  1.000 20.70797  ? 120 SER H N   1 
ATOM   899  C CA  . SER A 1 124 ? -13.45838 11.19385 13.61798  1.000 25.05208  ? 120 SER H CA  1 
ATOM   900  C C   . SER A 1 124 ? -13.43280 12.02545 14.89294  1.000 23.11749  ? 120 SER H C   1 
ATOM   901  O O   . SER A 1 124 ? -12.65368 11.74376 15.80511  1.000 27.00209  ? 120 SER H O   1 
ATOM   902  C CB  . SER A 1 124 ? -14.25552 9.90899  13.82508  1.000 18.65525  ? 120 SER H CB  1 
ATOM   903  O OG  . SER A 1 124 ? -14.28142 9.17936  12.61451  1.000 31.76889  ? 120 SER H OG  1 
ATOM   904  N N   . VAL A 1 125 ? -14.25766 13.05992 14.94201  1.000 20.37705  ? 121 VAL H N   1 
ATOM   905  C CA  . VAL A 1 125 ? -14.27969 13.99971 16.05534  1.000 20.21785  ? 121 VAL H CA  1 
ATOM   906  C C   . VAL A 1 125 ? -15.66049 13.92616 16.68882  1.000 23.24146  ? 121 VAL H C   1 
ATOM   907  O O   . VAL A 1 125 ? -16.67543 14.11648 16.00872  1.000 23.00934  ? 121 VAL H O   1 
ATOM   908  C CB  . VAL A 1 125 ? -13.94854 15.42883 15.60140  1.000 20.80027  ? 121 VAL H CB  1 
ATOM   909  C CG1 . VAL A 1 125 ? -13.94444 16.38024 16.78624  1.000 18.02236  ? 121 VAL H CG1 1 
ATOM   910  C CG2 . VAL A 1 125 ? -12.60328 15.45803 14.88389  1.000 20.94624  ? 121 VAL H CG2 1 
ATOM   911  N N   . PHE A 1 126 ? -15.70094 13.62839 17.97429  1.000 20.31107  ? 122 PHE H N   1 
ATOM   912  C CA  . PHE A 1 126 ? -16.96021 13.55314 18.67883  1.000 21.10658  ? 122 PHE H CA  1 
ATOM   913  C C   . PHE A 1 126 ? -16.94685 14.51416 19.86012  1.000 23.09388  ? 122 PHE H C   1 
ATOM   914  O O   . PHE A 1 126 ? -15.89605 14.73767 20.46761  1.000 20.35409  ? 122 PHE H O   1 
ATOM   915  C CB  . PHE A 1 126 ? -17.23224 12.13017 19.18355  1.000 19.49186  ? 122 PHE H CB  1 
ATOM   916  C CG  . PHE A 1 126 ? -17.18978 11.08891 18.09164  1.000 25.17492  ? 122 PHE H CG  1 
ATOM   917  C CD1 . PHE A 1 126 ? -18.17068 11.05701 17.10089  1.000 25.94447  ? 122 PHE H CD1 1 
ATOM   918  C CD2 . PHE A 1 126 ? -16.17313 10.13538 18.06131  1.000 27.82877  ? 122 PHE H CD2 1 
ATOM   919  C CE1 . PHE A 1 126 ? -18.13611 10.09532 16.08812  1.000 26.52583  ? 122 PHE H CE1 1 
ATOM   920  C CE2 . PHE A 1 126 ? -16.13249 9.16664  17.05625  1.000 24.73110  ? 122 PHE H CE2 1 
ATOM   921  C CZ  . PHE A 1 126 ? -17.11844 9.15244  16.06855  1.000 23.81073  ? 122 PHE H CZ  1 
ATOM   922  N N   . PRO A 1 127 ? -18.09624 15.08361 20.21789  1.000 21.18507  ? 123 PRO H N   1 
ATOM   923  C CA  . PRO A 1 127 ? -18.13391 16.01579 21.34321  1.000 22.10075  ? 123 PRO H CA  1 
ATOM   924  C C   . PRO A 1 127 ? -18.09784 15.26703 22.65723  1.000 21.68003  ? 123 PRO H C   1 
ATOM   925  O O   . PRO A 1 127 ? -18.62743 14.16213 22.78612  1.000 23.73006  ? 123 PRO H O   1 
ATOM   926  C CB  . PRO A 1 127 ? -19.47709 16.73717 21.16198  1.000 22.47319  ? 123 PRO H CB  1 
ATOM   927  C CG  . PRO A 1 127 ? -20.35124 15.69068 20.55410  1.000 23.52424  ? 123 PRO H CG  1 
ATOM   928  C CD  . PRO A 1 127 ? -19.43339 14.86639 19.64118  1.000 19.78504  ? 123 PRO H CD  1 
ATOM   929  N N   . LEU A 1 128 ? -17.42758 15.87674 23.63110  1.000 20.10127  ? 124 LEU H N   1 
ATOM   930  C CA  . LEU A 1 128 ? -17.54924 15.51652 25.04392  1.000 21.07042  ? 124 LEU H CA  1 
ATOM   931  C C   . LEU A 1 128 ? -18.36009 16.66188 25.65832  1.000 28.65873  ? 124 LEU H C   1 
ATOM   932  O O   . LEU A 1 128 ? -17.80982 17.68484 26.07310  1.000 20.28874  ? 124 LEU H O   1 
ATOM   933  C CB  . LEU A 1 128 ? -16.18763 15.34538 25.70867  1.000 18.94202  ? 124 LEU H CB  1 
ATOM   934  C CG  . LEU A 1 128 ? -15.29030 14.24131 25.13272  1.000 22.06588  ? 124 LEU H CG  1 
ATOM   935  C CD1 . LEU A 1 128 ? -13.83897 14.50732 25.51742  1.000 19.76593  ? 124 LEU H CD1 1 
ATOM   936  C CD2 . LEU A 1 128 ? -15.71597 12.86320 25.64787  1.000 17.43434  ? 124 LEU H CD2 1 
ATOM   937  N N   . ALA A 1 129 ? -19.67032 16.48837 25.69593  1.000 26.55732  ? 125 ALA H N   1 
ATOM   938  C CA  . ALA A 1 129 ? -20.54030 17.61983 25.97752  1.000 19.74185  ? 125 ALA H CA  1 
ATOM   939  C C   . ALA A 1 129 ? -20.63840 17.85745 27.48510  1.000 24.81845  ? 125 ALA H C   1 
ATOM   940  O O   . ALA A 1 129 ? -20.64100 16.90587 28.26580  1.000 24.03853  ? 125 ALA H O   1 
ATOM   941  C CB  . ALA A 1 129 ? -21.93036 17.37902 25.38831  1.000 24.46437  ? 125 ALA H CB  1 
ATOM   942  N N   . PRO A 1 130 ? -20.70209 19.11050 27.92231  1.000 22.26015  ? 126 PRO H N   1 
ATOM   943  C CA  . PRO A 1 130 ? -20.94911 19.37485 29.33982  1.000 25.88178  ? 126 PRO H CA  1 
ATOM   944  C C   . PRO A 1 130 ? -22.41111 19.11707 29.66419  1.000 33.05501  ? 126 PRO H C   1 
ATOM   945  O O   . PRO A 1 130 ? -23.29515 19.26050 28.81724  1.000 32.65215  ? 126 PRO H O   1 
ATOM   946  C CB  . PRO A 1 130 ? -20.60011 20.86097 29.48308  1.000 23.48175  ? 126 PRO H CB  1 
ATOM   947  C CG  . PRO A 1 130 ? -21.00387 21.44074 28.14490  1.000 29.81108  ? 126 PRO H CG  1 
ATOM   948  C CD  . PRO A 1 130 ? -20.74954 20.34546 27.11197  1.000 26.19218  ? 126 PRO H CD  1 
ATOM   949  N N   . SER A 1 131 ? -22.66260 18.69798 30.89684  1.000 33.88003  ? 127 SER H N   1 
ATOM   950  C CA  . SER A 1 131 ? -24.04360 18.63626 31.36208  1.000 47.82130  ? 127 SER H CA  1 
ATOM   951  C C   . SER A 1 131 ? -24.62602 20.04518 31.47191  1.000 49.05345  ? 127 SER H C   1 
ATOM   952  O O   . SER A 1 131 ? -23.91836 21.01335 31.77681  1.000 40.52312  ? 127 SER H O   1 
ATOM   953  C CB  . SER A 1 131 ? -24.13288 17.92450 32.71192  1.000 40.77427  ? 127 SER H CB  1 
ATOM   954  O OG  . SER A 1 131 ? -23.26439 18.53007 33.65375  1.000 49.07431  ? 127 SER H OG  1 
ATOM   955  N N   . SER A 1 132 ? -25.93528 20.15276 31.21085  1.000 54.49332  ? 128 SER H N   1 
ATOM   956  C CA  . SER A 1 132 ? -26.59976 21.45566 31.24065  1.000 54.98728  ? 128 SER H CA  1 
ATOM   957  C C   . SER A 1 132 ? -26.47479 22.11807 32.61188  1.000 55.49590  ? 128 SER H C   1 
ATOM   958  O O   . SER A 1 132 ? -26.15821 23.31147 32.70847  1.000 55.23800  ? 128 SER H O   1 
ATOM   959  C CB  . SER A 1 132 ? -28.06897 21.29992 30.84426  1.000 59.87159  ? 128 SER H CB  1 
ATOM   960  O OG  . SER A 1 132 ? -28.72773 22.55405 30.81126  1.000 60.44742  ? 128 SER H OG  1 
ATOM   961  N N   . LYS A 1 133 ? -26.72351 21.36780 33.68090  1.000 58.24056  ? 129 LYS H N   1 
ATOM   962  C CA  . LYS A 1 133 ? -26.43486 21.82719 35.03288  1.000 56.30101  ? 129 LYS H CA  1 
ATOM   963  C C   . LYS A 1 133 ? -25.15656 21.15619 35.51742  1.000 52.31443  ? 129 LYS H C   1 
ATOM   964  O O   . LYS A 1 133 ? -25.01812 19.93218 35.42256  1.000 50.86140  ? 129 LYS H O   1 
ATOM   965  C CB  . LYS A 1 133 ? -27.59953 21.53705 35.98372  1.000 57.93304  ? 129 LYS H CB  1 
ATOM   966  C CG  . LYS A 1 133 ? -28.68302 22.61557 35.98154  1.000 62.12222  ? 129 LYS H CG  1 
ATOM   967  C CD  . LYS A 1 133 ? -28.15994 23.95432 36.51022  1.000 68.20098  ? 129 LYS H CD  1 
ATOM   968  C CE  . LYS A 1 133 ? -28.03372 23.95463 38.03479  1.000 59.29324  ? 129 LYS H CE  1 
ATOM   969  N NZ  . LYS A 1 133 ? -27.56128 25.27079 38.56900  1.000 63.70655  ? 129 LYS H NZ  1 
ATOM   970  N N   . SER A 1 134 ? -24.21996 21.96242 36.01215  1.000 52.34096  ? 130 SER H N   1 
ATOM   971  C CA  . SER A 1 134 ? -22.93638 21.44019 36.45660  1.000 53.57527  ? 130 SER H CA  1 
ATOM   972  C C   . SER A 1 134 ? -23.08311 20.67750 37.76958  1.000 54.08705  ? 130 SER H C   1 
ATOM   973  O O   . SER A 1 134 ? -24.01736 20.89927 38.54837  1.000 40.69402  ? 130 SER H O   1 
ATOM   974  C CB  . SER A 1 134 ? -21.92377 22.57469 36.63096  1.000 56.45031  ? 130 SER H CB  1 
ATOM   975  O OG  . SER A 1 134 ? -20.84842 22.19131 37.48407  1.000 53.26583  ? 130 SER H OG  1 
ATOM   976  N N   . THR A 1 135 ? -22.14263 19.76072 38.00559  1.000 36.57458  ? 131 THR H N   1 
ATOM   977  C CA  . THR A 1 135 ? -22.05003 19.05253 39.27539  1.000 39.41361  ? 131 THR H CA  1 
ATOM   978  C C   . THR A 1 135 ? -20.63338 19.14057 39.83925  1.000 40.24932  ? 131 THR H C   1 
ATOM   979  O O   . THR A 1 135 ? -20.17736 18.22302 40.52983  1.000 35.77744  ? 131 THR H O   1 
ATOM   980  C CB  . THR A 1 135 ? -22.49288 17.59178 39.13399  1.000 34.91735  ? 131 THR H CB  1 
ATOM   981  O OG1 . THR A 1 135 ? -21.75115 16.94587 38.08348  1.000 42.43642  ? 131 THR H OG1 1 
ATOM   982  C CG2 . THR A 1 135 ? -24.00526 17.50476 38.83987  1.000 32.19739  ? 131 THR H CG2 1 
ATOM   983  N N   . SER A 1 136 ? -19.93613 20.24697 39.56773  1.000 34.09096  ? 132 SER H N   1 
ATOM   984  C CA  . SER A 1 136 ? -18.54522 20.43123 39.97576  1.000 36.52858  ? 132 SER H CA  1 
ATOM   985  C C   . SER A 1 136 ? -18.29714 21.85455 40.47722  1.000 38.96155  ? 132 SER H C   1 
ATOM   986  O O   . SER A 1 136 ? -17.31761 22.50663 40.10792  1.000 38.11656  ? 132 SER H O   1 
ATOM   987  C CB  . SER A 1 136 ? -17.60471 20.09591 38.82206  1.000 40.27335  ? 132 SER H CB  1 
ATOM   988  O OG  . SER A 1 136 ? -17.91474 18.81939 38.28540  1.000 52.54859  ? 132 SER H OG  1 
ATOM   989  N N   . GLY A 1 137 ? -19.18138 22.34400 41.34318  1.000 34.12725  ? 133 GLY H N   1 
ATOM   990  C CA  . GLY A 1 137 ? -18.93809 23.60614 42.03996  1.000 28.75681  ? 133 GLY H CA  1 
ATOM   991  C C   . GLY A 1 137 ? -18.80159 24.83018 41.15639  1.000 36.93971  ? 133 GLY H C   1 
ATOM   992  O O   . GLY A 1 137 ? -18.00656 25.72765 41.46436  1.000 42.49298  ? 133 GLY H O   1 
ATOM   993  N N   . GLY A 1 138 ? -19.56305 24.89787 40.06723  1.000 29.03992  ? 134 GLY H N   1 
ATOM   994  C CA  . GLY A 1 138 ? -19.52769 26.06574 39.20910  1.000 35.75705  ? 134 GLY H CA  1 
ATOM   995  C C   . GLY A 1 138 ? -18.56267 25.98854 38.04718  1.000 31.98896  ? 134 GLY H C   1 
ATOM   996  O O   . GLY A 1 138 ? -18.50479 26.93385 37.24890  1.000 37.44306  ? 134 GLY H O   1 
ATOM   997  N N   . THR A 1 139 ? -17.81430 24.89642 37.91736  1.000 29.58980  ? 135 THR H N   1 
ATOM   998  C CA  . THR A 1 139 ? -16.93962 24.65754 36.77516  1.000 29.05559  ? 135 THR H CA  1 
ATOM   999  C C   . THR A 1 139 ? -17.51291 23.53442 35.91762  1.000 36.96863  ? 135 THR H C   1 
ATOM   1000 O O   . THR A 1 139 ? -17.97604 22.51711 36.44261  1.000 36.05355  ? 135 THR H O   1 
ATOM   1001 C CB  . THR A 1 139 ? -15.53478 24.28068 37.23893  1.000 31.59985  ? 135 THR H CB  1 
ATOM   1002 O OG1 . THR A 1 139 ? -14.91690 25.41454 37.85607  1.000 27.62629  ? 135 THR H OG1 1 
ATOM   1003 C CG2 . THR A 1 139 ? -14.68817 23.81922 36.07154  1.000 39.60593  ? 135 THR H CG2 1 
ATOM   1004 N N   . ALA A 1 140 ? -17.48050 23.71359 34.60169  1.000 25.13198  ? 136 ALA H N   1 
ATOM   1005 C CA  . ALA A 1 140 ? -17.92677 22.69315 33.66595  1.000 25.94471  ? 136 ALA H CA  1 
ATOM   1006 C C   . ALA A 1 140 ? -16.73885 22.20150 32.85066  1.000 26.38496  ? 136 ALA H C   1 
ATOM   1007 O O   . ALA A 1 140 ? -15.85090 22.98460 32.50285  1.000 28.81061  ? 136 ALA H O   1 
ATOM   1008 C CB  . ALA A 1 140 ? -19.00904 23.23472 32.73535  1.000 24.44496  ? 136 ALA H CB  1 
ATOM   1009 N N   . ALA A 1 141 ? -16.70971 20.90651 32.56337  1.000 27.26588  ? 137 ALA H N   1 
ATOM   1010 C CA  . ALA A 1 141 ? -15.71764 20.34162 31.65950  1.000 26.46043  ? 137 ALA H CA  1 
ATOM   1011 C C   . ALA A 1 141 ? -16.38477 20.00462 30.33742  1.000 19.16101  ? 137 ALA H C   1 
ATOM   1012 O O   . ALA A 1 141 ? -17.52374 19.52636 30.30227  1.000 23.54063  ? 137 ALA H O   1 
ATOM   1013 C CB  . ALA A 1 141 ? -15.05364 19.09379 32.26078  1.000 21.68130  ? 137 ALA H CB  1 
ATOM   1014 N N   . LEU A 1 142 ? -15.69593 20.29839 29.24239  1.000 19.40482  ? 138 LEU H N   1 
ATOM   1015 C CA  . LEU A 1 142 ? -16.18108 19.92612 27.92722  1.000 20.71323  ? 138 LEU H CA  1 
ATOM   1016 C C   . LEU A 1 142 ? -14.96019 19.62837 27.06935  1.000 19.06064  ? 138 LEU H C   1 
ATOM   1017 O O   . LEU A 1 142 ? -13.82283 19.87764 27.46848  1.000 20.69514  ? 138 LEU H O   1 
ATOM   1018 C CB  . LEU A 1 142 ? -17.05378 21.02468 27.31226  1.000 18.73172  ? 138 LEU H CB  1 
ATOM   1019 C CG  . LEU A 1 142 ? -16.29416 22.33087 27.11204  1.000 24.47470  ? 138 LEU H CG  1 
ATOM   1020 C CD1 . LEU A 1 142 ? -16.10958 22.56265 25.64026  1.000 26.34449  ? 138 LEU H CD1 1 
ATOM   1021 C CD2 . LEU A 1 142 ? -17.03477 23.49480 27.75835  1.000 27.12207  ? 138 LEU H CD2 1 
ATOM   1022 N N   . GLY A 1 143 ? -15.19231 19.08698 25.88395  1.000 21.20434  ? 139 GLY H N   1 
ATOM   1023 C CA  . GLY A 1 143 ? -14.05317 18.72966 25.06772  1.000 16.55765  ? 139 GLY H CA  1 
ATOM   1024 C C   . GLY A 1 143 ? -14.47882 18.07169 23.77731  1.000 16.38994  ? 139 GLY H C   1 
ATOM   1025 O O   . GLY A 1 143 ? -15.65418 18.06766 23.40779  1.000 19.02599  ? 139 GLY H O   1 
ATOM   1026 N N   . CYS A 1 144 ? -13.49029 17.53114 23.07521  1.000 18.43032  ? 140 CYS H N   1 
ATOM   1027 C CA  A CYS A 1 144 ? -13.71317 16.76867 21.85433  0.755 19.41636  ? 140 CYS H CA  1 
ATOM   1028 C CA  B CYS A 1 144 ? -13.81728 16.69191 21.94261  0.245 19.36927  ? 140 CYS H CA  1 
ATOM   1029 C C   . CYS A 1 144 ? -12.84802 15.52034 21.88270  1.000 20.56751  ? 140 CYS H C   1 
ATOM   1030 O O   . CYS A 1 144 ? -11.67111 15.60767 22.24876  1.000 17.86862  ? 140 CYS H O   1 
ATOM   1031 C CB  A CYS A 1 144 ? -13.36526 17.59204 20.61752  0.755 18.45987  ? 140 CYS H CB  1 
ATOM   1032 C CB  B CYS A 1 144 ? -13.90541 17.48993 20.60579  0.245 19.69037  ? 140 CYS H CB  1 
ATOM   1033 S SG  A CYS A 1 144 ? -14.46439 18.99463 20.24664  0.755 23.62228  ? 140 CYS H SG  1 
ATOM   1034 S SG  B CYS A 1 144 ? -12.51426 18.46033 19.93431  0.245 24.23611  ? 140 CYS H SG  1 
ATOM   1035 N N   . LEU A 1 145 ? -13.41297 14.39262 21.48729  1.000 20.24648  ? 141 LEU H N   1 
ATOM   1036 C CA  . LEU A 1 145 ? -12.70516 13.13580 21.35217  1.000 20.97479  ? 141 LEU H CA  1 
ATOM   1037 C C   . LEU A 1 145 ? -12.29109 13.00256 19.89271  1.000 17.00142  ? 141 LEU H C   1 
ATOM   1038 O O   . LEU A 1 145 ? -13.13084 13.13995 18.99174  1.000 17.74793  ? 141 LEU H O   1 
ATOM   1039 C CB  . LEU A 1 145 ? -13.60288 11.97359 21.78635  1.000 17.53652  ? 141 LEU H CB  1 
ATOM   1040 C CG  . LEU A 1 145 ? -13.10397 10.55851 21.47862  1.000 23.26086  ? 141 LEU H CG  1 
ATOM   1041 C CD1 . LEU A 1 145 ? -11.80335 10.33059 22.17074  1.000 20.36204  ? 141 LEU H CD1 1 
ATOM   1042 C CD2 . LEU A 1 145 ? -14.11867 9.48503  21.90218  1.000 24.13900  ? 141 LEU H CD2 1 
ATOM   1043 N N   . VAL A 1 146 ? -11.00180 12.78589 19.65716  1.000 14.03209  ? 142 VAL H N   1 
ATOM   1044 C CA  . VAL A 1 146 ? -10.44528 12.74745 18.30613  1.000 21.99320  ? 142 VAL H CA  1 
ATOM   1045 C C   . VAL A 1 146 ? -9.96874  11.31776 18.07247  1.000 23.69421  ? 142 VAL H C   1 
ATOM   1046 O O   . VAL A 1 146 ? -8.91244  10.92033 18.57677  1.000 24.88865  ? 142 VAL H O   1 
ATOM   1047 C CB  . VAL A 1 146 ? -9.30885  13.76019 18.12693  1.000 21.25405  ? 142 VAL H CB  1 
ATOM   1048 C CG1 . VAL A 1 146 ? -8.75016  13.68106 16.70741  1.000 28.03687  ? 142 VAL H CG1 1 
ATOM   1049 C CG2 . VAL A 1 146 ? -9.79241  15.17372 18.40403  1.000 23.36676  ? 142 VAL H CG2 1 
ATOM   1050 N N   . LYS A 1 147 ? -10.72858 10.53446 17.30444  1.000 24.45840  ? 143 LYS H N   1 
ATOM   1051 C CA  . LYS A 1 147 ? -10.56829 9.08447  17.30780  1.000 25.50821  ? 143 LYS H CA  1 
ATOM   1052 C C   . LYS A 1 147 ? -10.14723 8.55060  15.94134  1.000 24.17792  ? 143 LYS H C   1 
ATOM   1053 O O   . LYS A 1 147 ? -10.61503 9.02573  14.89889  1.000 21.99013  ? 143 LYS H O   1 
ATOM   1054 C CB  . LYS A 1 147 ? -11.86742 8.40103  17.76228  1.000 30.62448  ? 143 LYS H CB  1 
ATOM   1055 C CG  . LYS A 1 147 ? -11.65298 7.12454  18.54649  1.000 30.18643  ? 143 LYS H CG  1 
ATOM   1056 C CD  . LYS A 1 147 ? -12.96781 6.52785  19.00186  1.000 35.52160  ? 143 LYS H CD  1 
ATOM   1057 C CE  . LYS A 1 147 ? -12.99410 5.02777  18.75432  1.000 40.02933  ? 143 LYS H CE  1 
ATOM   1058 N NZ  . LYS A 1 147 ? -11.76891 4.36618  19.26108  1.000 40.98381  ? 143 LYS H NZ  1 
ATOM   1059 N N   . ASP A 1 148 ? -9.23280  7.57781  15.96378  1.000 20.64631  ? 144 ASP H N   1 
ATOM   1060 C CA  . ASP A 1 148 ? -8.93447  6.71791  14.81925  1.000 19.39055  ? 144 ASP H CA  1 
ATOM   1061 C C   . ASP A 1 148 ? -8.23886  7.41326  13.65221  1.000 23.79316  ? 144 ASP H C   1 
ATOM   1062 O O   . ASP A 1 148 ? -8.68848  7.31192  12.50041  1.000 24.49974  ? 144 ASP H O   1 
ATOM   1063 C CB  . ASP A 1 148 ? -10.22909 6.05754  14.33814  1.000 20.30135  ? 144 ASP H CB  1 
ATOM   1064 C CG  . ASP A 1 148 ? -10.74623 5.04556  15.32451  1.000 27.42111  ? 144 ASP H CG  1 
ATOM   1065 O OD1 . ASP A 1 148 ? -9.95904  4.63113  16.20354  1.000 34.51804  ? 144 ASP H OD1 1 
ATOM   1066 O OD2 . ASP A 1 148 ? -11.93146 4.65725  15.24176  1.000 30.54543  ? 144 ASP H OD2 1 
ATOM   1067 N N   . TYR A 1 149 ? -7.11395  8.07548  13.90508  1.000 19.00783  ? 145 TYR H N   1 
ATOM   1068 C CA  . TYR A 1 149 ? -6.38144  8.72916  12.83366  1.000 16.28143  ? 145 TYR H CA  1 
ATOM   1069 C C   . TYR A 1 149 ? -4.96533  8.17069  12.73115  1.000 19.07109  ? 145 TYR H C   1 
ATOM   1070 O O   . TYR A 1 149 ? -4.43953  7.57923  13.67368  1.000 17.05530  ? 145 TYR H O   1 
ATOM   1071 C CB  . TYR A 1 149 ? -6.33326  10.24940 13.04573  1.000 18.47939  ? 145 TYR H CB  1 
ATOM   1072 C CG  . TYR A 1 149 ? -5.57635  10.67250 14.28558  1.000 16.87766  ? 145 TYR H CG  1 
ATOM   1073 C CD1 . TYR A 1 149 ? -4.21361  10.92890 14.24060  1.000 20.49679  ? 145 TYR H CD1 1 
ATOM   1074 C CD2 . TYR A 1 149 ? -6.22827  10.81223 15.50379  1.000 16.75867  ? 145 TYR H CD2 1 
ATOM   1075 C CE1 . TYR A 1 149 ? -3.52787  11.32163 15.37411  1.000 21.86006  ? 145 TYR H CE1 1 
ATOM   1076 C CE2 . TYR A 1 149 ? -5.55190  11.19591 16.62775  1.000 16.42570  ? 145 TYR H CE2 1 
ATOM   1077 C CZ  . TYR A 1 149 ? -4.21047  11.44824 16.55931  1.000 19.33745  ? 145 TYR H CZ  1 
ATOM   1078 O OH  . TYR A 1 149 ? -3.54743  11.81745 17.69254  1.000 19.96892  ? 145 TYR H OH  1 
ATOM   1079 N N   . PHE A 1 150 ? -4.33735  8.39110  11.56932  1.000 16.64807  ? 146 PHE H N   1 
ATOM   1080 C CA  . PHE A 1 150 ? -2.95484  7.98239  11.33308  1.000 16.50688  ? 146 PHE H CA  1 
ATOM   1081 C C   . PHE A 1 150 ? -2.41031  8.79295  10.16928  1.000 18.17957  ? 146 PHE H C   1 
ATOM   1082 O O   . PHE A 1 150 ? -3.16905  9.08184  9.23848   1.000 18.89141  ? 146 PHE H O   1 
ATOM   1083 C CB  . PHE A 1 150 ? -2.86217  6.47954  11.02426  1.000 21.46052  ? 146 PHE H CB  1 
ATOM   1084 C CG  . PHE A 1 150 ? -1.44820  5.95598  11.00755  1.000 20.42642  ? 146 PHE H CG  1 
ATOM   1085 C CD1 . PHE A 1 150 ? -0.85079  5.50138  12.17779  1.000 18.54661  ? 146 PHE H CD1 1 
ATOM   1086 C CD2 . PHE A 1 150 ? -0.70232  5.95397  9.83692   1.000 19.49436  ? 146 PHE H CD2 1 
ATOM   1087 C CE1 . PHE A 1 150 ? 0.45874   5.04199  12.18360  1.000 21.43204  ? 146 PHE H CE1 1 
ATOM   1088 C CE2 . PHE A 1 150 ? 0.62027   5.48402  9.82974   1.000 17.66268  ? 146 PHE H CE2 1 
ATOM   1089 C CZ  . PHE A 1 150 ? 1.19949   5.03567  11.00889  1.000 19.67710  ? 146 PHE H CZ  1 
ATOM   1090 N N   . PRO A 1 151 ? -1.13997  9.22328  10.19994  1.000 17.19114  ? 147 PRO H N   1 
ATOM   1091 C CA  . PRO A 1 151 ? -0.23904  9.11795  11.34988  1.000 15.53428  ? 147 PRO H CA  1 
ATOM   1092 C C   . PRO A 1 151 ? -0.42912  10.29643 12.30681  1.000 22.47185  ? 147 PRO H C   1 
ATOM   1093 O O   . PRO A 1 151 ? -1.37247  11.05641 12.14618  1.000 16.75717  ? 147 PRO H O   1 
ATOM   1094 C CB  . PRO A 1 151 ? 1.13557   9.19595  10.70198  1.000 16.21857  ? 147 PRO H CB  1 
ATOM   1095 C CG  . PRO A 1 151 ? 0.91381   10.17719 9.59706   1.000 22.27229  ? 147 PRO H CG  1 
ATOM   1096 C CD  . PRO A 1 151 ? -0.44446  9.79752  9.03355   1.000 16.92941  ? 147 PRO H CD  1 
ATOM   1097 N N   . GLU A 1 152 ? 0.48624   10.48690 13.25073  1.000 22.19405  ? 148 GLU H N   1 
ATOM   1098 C CA  . GLU A 1 152 ? 0.49311   11.72819 14.00358  1.000 24.08998  ? 148 GLU H CA  1 
ATOM   1099 C C   . GLU A 1 152 ? 1.02635   12.84896 13.11315  1.000 23.20299  ? 148 GLU H C   1 
ATOM   1100 O O   . GLU A 1 152 ? 1.61664   12.58769 12.06656  1.000 18.90655  ? 148 GLU H O   1 
ATOM   1101 C CB  . GLU A 1 152 ? 1.34261   11.57094 15.26335  1.000 24.71897  ? 148 GLU H CB  1 
ATOM   1102 C CG  . GLU A 1 152 ? 0.85050   10.46716 16.14319  1.000 24.29092  ? 148 GLU H CG  1 
ATOM   1103 C CD  . GLU A 1 152 ? 1.19578   10.68243 17.60739  1.000 46.61050  ? 148 GLU H CD  1 
ATOM   1104 O OE1 . GLU A 1 152 ? 0.69835   11.66475 18.20449  1.000 33.60923  ? 148 GLU H OE1 1 
ATOM   1105 O OE2 . GLU A 1 152 ? 1.96450   9.86634  18.16650  1.000 47.30927  ? 148 GLU H OE2 1 
ATOM   1106 N N   . PRO A 1 153 ? 0.81780   14.11680 13.49265  1.000 25.00739  ? 149 PRO H N   1 
ATOM   1107 C CA  . PRO A 1 153 ? 0.12033   14.65884 14.66018  1.000 24.90898  ? 149 PRO H CA  1 
ATOM   1108 C C   . PRO A 1 153 ? -1.25018  15.19927 14.29693  1.000 20.83358  ? 149 PRO H C   1 
ATOM   1109 O O   . PRO A 1 153 ? -1.50403  15.46236 13.12458  1.000 21.67334  ? 149 PRO H O   1 
ATOM   1110 C CB  . PRO A 1 153 ? 1.03927   15.80021 15.09368  1.000 22.26170  ? 149 PRO H CB  1 
ATOM   1111 C CG  . PRO A 1 153 ? 1.50247   16.37062 13.75892  1.000 23.85724  ? 149 PRO H CG  1 
ATOM   1112 C CD  . PRO A 1 153 ? 1.54118   15.17866 12.77016  1.000 16.85214  ? 149 PRO H CD  1 
ATOM   1113 N N   . VAL A 1 154 ? -2.13515  15.32696 15.27442  1.000 23.80362  ? 150 VAL H N   1 
ATOM   1114 C CA  . VAL A 1 154 ? -3.25778  16.24598 15.16976  1.000 21.16305  ? 150 VAL H CA  1 
ATOM   1115 C C   . VAL A 1 154 ? -2.96897  17.39015 16.12641  1.000 24.65841  ? 150 VAL H C   1 
ATOM   1116 O O   . VAL A 1 154 ? -2.34703  17.20000 17.17547  1.000 28.41992  ? 150 VAL H O   1 
ATOM   1117 C CB  . VAL A 1 154 ? -4.62735  15.59850 15.49250  1.000 26.67581  ? 150 VAL H CB  1 
ATOM   1118 C CG1 . VAL A 1 154 ? -4.92352  14.45517 14.56541  1.000 23.85917  ? 150 VAL H CG1 1 
ATOM   1119 C CG2 . VAL A 1 154 ? -4.66619  15.13042 16.90328  1.000 30.64548  ? 150 VAL H CG2 1 
ATOM   1120 N N   . THR A 1 155 ? -3.39224  18.59149 15.75582  1.000 26.08325  ? 151 THR H N   1 
ATOM   1121 C CA  . THR A 1 155 ? -3.37660  19.71037 16.68447  1.000 26.17023  ? 151 THR H CA  1 
ATOM   1122 C C   . THR A 1 155 ? -4.80772  20.11362 17.00378  1.000 23.20579  ? 151 THR H C   1 
ATOM   1123 O O   . THR A 1 155 ? -5.70690  19.98876 16.16663  1.000 24.06082  ? 151 THR H O   1 
ATOM   1124 C CB  . THR A 1 155 ? -2.60619  20.91142 16.12948  1.000 31.95904  ? 151 THR H CB  1 
ATOM   1125 O OG1 . THR A 1 155 ? -3.16712  21.30616 14.86672  1.000 28.93887  ? 151 THR H OG1 1 
ATOM   1126 C CG2 . THR A 1 155 ? -1.13742  20.55318 15.95170  1.000 29.53432  ? 151 THR H CG2 1 
ATOM   1127 N N   . VAL A 1 156 ? -5.02800  20.56253 18.23697  1.000 20.28624  ? 152 VAL H N   1 
ATOM   1128 C CA  . VAL A 1 156 ? -6.34571  21.03509 18.64796  1.000 20.53957  ? 152 VAL H CA  1 
ATOM   1129 C C   . VAL A 1 156 ? -6.22183  22.44505 19.21204  1.000 22.77846  ? 152 VAL H C   1 
ATOM   1130 O O   . VAL A 1 156 ? -5.34565  22.72162 20.04148  1.000 24.44023  ? 152 VAL H O   1 
ATOM   1131 C CB  . VAL A 1 156 ? -6.99889  20.09828 19.67580  1.000 19.40286  ? 152 VAL H CB  1 
ATOM   1132 C CG1 . VAL A 1 156 ? -8.46493  20.51066 19.90231  1.000 18.91481  ? 152 VAL H CG1 1 
ATOM   1133 C CG2 . VAL A 1 156 ? -6.91435  18.66183 19.20099  1.000 17.53250  ? 152 VAL H CG2 1 
ATOM   1134 N N   . SER A 1 157 ? -7.08929  23.33722 18.75955  1.000 21.14086  ? 153 SER H N   1 
ATOM   1135 C CA  . SER A 1 157 ? -7.24884  24.62869 19.41255  1.000 20.05360  ? 153 SER H CA  1 
ATOM   1136 C C   . SER A 1 157 ? -8.72137  24.80085 19.75658  1.000 24.02234  ? 153 SER H C   1 
ATOM   1137 O O   . SER A 1 157 ? -9.57497  24.00585 19.34717  1.000 25.94722  ? 153 SER H O   1 
ATOM   1138 C CB  . SER A 1 157 ? -6.73187  25.77775 18.53122  1.000 24.21803  ? 153 SER H CB  1 
ATOM   1139 O OG  . SER A 1 157 ? -7.46835  25.85834 17.31570  1.000 25.35281  ? 153 SER H OG  1 
ATOM   1140 N N   . TRP A 1 158 ? -9.01716  25.81641 20.56298  1.000 22.28925  ? 154 TRP H N   1 
ATOM   1141 C CA  . TRP A 1 158 ? -10.38702 26.12719 20.94133  1.000 23.70257  ? 154 TRP H CA  1 
ATOM   1142 C C   . TRP A 1 158 ? -10.71234 27.55681 20.53270  1.000 21.88900  ? 154 TRP H C   1 
ATOM   1143 O O   . TRP A 1 158 ? -9.90138  28.46527 20.73226  1.000 22.35155  ? 154 TRP H O   1 
ATOM   1144 C CB  . TRP A 1 158 ? -10.60439 25.91336 22.44154  1.000 19.25036  ? 154 TRP H CB  1 
ATOM   1145 C CG  . TRP A 1 158 ? -10.66710 24.46106 22.79142  1.000 16.98929  ? 154 TRP H CG  1 
ATOM   1146 C CD1 . TRP A 1 158 ? -9.61682  23.64120 23.10338  1.000 20.00972  ? 154 TRP H CD1 1 
ATOM   1147 C CD2 . TRP A 1 158 ? -11.84521 23.64114 22.82695  1.000 20.33731  ? 154 TRP H CD2 1 
ATOM   1148 N NE1 . TRP A 1 158 ? -10.07650 22.36076 23.35718  1.000 16.85747  ? 154 TRP H NE1 1 
ATOM   1149 C CE2 . TRP A 1 158 ? -11.43864 22.33723 23.18314  1.000 20.90318  ? 154 TRP H CE2 1 
ATOM   1150 C CE3 . TRP A 1 158 ? -13.20697 23.88536 22.59252  1.000 18.53578  ? 154 TRP H CE3 1 
ATOM   1151 C CZ2 . TRP A 1 158 ? -12.34980 21.28043 23.31868  1.000 20.16171  ? 154 TRP H CZ2 1 
ATOM   1152 C CZ3 . TRP A 1 158 ? -14.11475 22.83581 22.73060  1.000 22.94450  ? 154 TRP H CZ3 1 
ATOM   1153 C CH2 . TRP A 1 158 ? -13.68094 21.55230 23.09665  1.000 19.10030  ? 154 TRP H CH2 1 
ATOM   1154 N N   . ASN A 1 159 ? -11.89062 27.73843 19.94073  1.000 20.01548  ? 155 ASN H N   1 
ATOM   1155 C CA  . ASN A 1 159 ? -12.32410 29.03571 19.42859  1.000 26.20178  ? 155 ASN H CA  1 
ATOM   1156 C C   . ASN A 1 159 ? -11.20233 29.72540 18.64385  1.000 27.25254  ? 155 ASN H C   1 
ATOM   1157 O O   . ASN A 1 159 ? -10.86806 30.89270 18.86984  1.000 29.68560  ? 155 ASN H O   1 
ATOM   1158 C CB  . ASN A 1 159 ? -12.84561 29.89611 20.57676  1.000 24.01906  ? 155 ASN H CB  1 
ATOM   1159 C CG  . ASN A 1 159 ? -14.06569 29.27512 21.23621  1.000 28.13342  ? 155 ASN H CG  1 
ATOM   1160 O OD1 . ASN A 1 159 ? -14.70312 28.38959 20.66113  1.000 29.06071  ? 155 ASN H OD1 1 
ATOM   1161 N ND2 . ASN A 1 159 ? -14.40048 29.73045 22.43638  1.000 27.22716  ? 155 ASN H ND2 1 
ATOM   1162 N N   . SER A 1 160 ? -10.59543 28.95694 17.73045  1.000 25.59028  ? 156 SER H N   1 
ATOM   1163 C CA  . SER A 1 160 ? -9.53181  29.42535 16.83244  1.000 28.31987  ? 156 SER H CA  1 
ATOM   1164 C C   . SER A 1 160 ? -8.35884  30.04535 17.58809  1.000 35.81051  ? 156 SER H C   1 
ATOM   1165 O O   . SER A 1 160 ? -7.72253  30.98232 17.10061  1.000 34.91075  ? 156 SER H O   1 
ATOM   1166 C CB  . SER A 1 160 ? -10.07590 30.41801 15.80016  1.000 27.90548  ? 156 SER H CB  1 
ATOM   1167 O OG  . SER A 1 160 ? -11.17595 29.86193 15.09974  1.000 32.62790  ? 156 SER H OG  1 
ATOM   1168 N N   . GLY A 1 161 ? -8.05615  29.54019 18.78043  1.000 28.20514  ? 157 GLY H N   1 
ATOM   1169 C CA  . GLY A 1 161 ? -6.94008  30.05222 19.55148  1.000 27.36887  ? 157 GLY H CA  1 
ATOM   1170 C C   . GLY A 1 161 ? -7.28810  31.11764 20.57032  1.000 25.40685  ? 157 GLY H C   1 
ATOM   1171 O O   . GLY A 1 161 ? -6.40547  31.53643 21.32622  1.000 30.60156  ? 157 GLY H O   1 
ATOM   1172 N N   . ALA A 1 162 ? -8.54265  31.56825 20.62181  1.000 28.35928  ? 158 ALA H N   1 
ATOM   1173 C CA  . ALA A 1 162 ? -8.93909  32.56739 21.60588  1.000 30.20235  ? 158 ALA H CA  1 
ATOM   1174 C C   . ALA A 1 162 ? -9.11351  31.98252 23.00046  1.000 33.55900  ? 158 ALA H C   1 
ATOM   1175 O O   . ALA A 1 162 ? -9.14946  32.73672 23.97859  1.000 36.25388  ? 158 ALA H O   1 
ATOM   1176 C CB  . ALA A 1 162 ? -10.24004 33.24655 21.17126  1.000 25.53068  ? 158 ALA H CB  1 
ATOM   1177 N N   . LEU A 1 163 ? -9.23097  30.66589 23.11973  1.000 26.67158  ? 159 LEU H N   1 
ATOM   1178 C CA  . LEU A 1 163 ? -9.44266  30.01374 24.40434  1.000 20.27064  ? 159 LEU H CA  1 
ATOM   1179 C C   . LEU A 1 163 ? -8.25050  29.10469 24.65466  1.000 27.84564  ? 159 LEU H C   1 
ATOM   1180 O O   . LEU A 1 163 ? -8.06592  28.11177 23.93924  1.000 20.22503  ? 159 LEU H O   1 
ATOM   1181 C CB  . LEU A 1 163 ? -10.75415 29.23845 24.40209  1.000 25.05620  ? 159 LEU H CB  1 
ATOM   1182 C CG  . LEU A 1 163 ? -11.02533 28.36057 25.61998  1.000 26.31128  ? 159 LEU H CG  1 
ATOM   1183 C CD1 . LEU A 1 163 ? -11.01899 29.18488 26.90768  1.000 28.11671  ? 159 LEU H CD1 1 
ATOM   1184 C CD2 . LEU A 1 163 ? -12.35226 27.60620 25.44512  1.000 28.05040  ? 159 LEU H CD2 1 
ATOM   1185 N N   . THR A 1 164 ? -7.41921  29.46817 25.64009  1.000 23.28224  ? 160 THR H N   1 
ATOM   1186 C CA  . THR A 1 164 ? -6.21092  28.70808 25.94787  1.000 23.18255  ? 160 THR H CA  1 
ATOM   1187 C C   . THR A 1 164 ? -6.17087  28.31675 27.41654  1.000 25.52342  ? 160 THR H C   1 
ATOM   1188 O O   . THR A 1 164 ? -5.63948  27.25624 27.75861  1.000 24.63795  ? 160 THR H O   1 
ATOM   1189 C CB  . THR A 1 164 ? -4.93858  29.49641 25.60324  1.000 28.12182  ? 160 THR H CB  1 
ATOM   1190 O OG1 . THR A 1 164 ? -4.99254  30.78297 26.23220  1.000 34.81598  ? 160 THR H OG1 1 
ATOM   1191 C CG2 . THR A 1 164 ? -4.77525  29.66371 24.09187  1.000 30.77176  ? 160 THR H CG2 1 
ATOM   1192 N N   . SER A 1 165 ? -6.72419  29.16386 28.28919  1.000 26.61334  ? 161 SER H N   1 
ATOM   1193 C CA  . SER A 1 165 ? -6.70169  28.90152 29.72300  1.000 25.59310  ? 161 SER H CA  1 
ATOM   1194 C C   . SER A 1 165 ? -7.53937  27.67743 30.05660  1.000 20.13675  ? 161 SER H C   1 
ATOM   1195 O O   . SER A 1 165 ? -8.70939  27.59182 29.67667  1.000 27.15339  ? 161 SER H O   1 
ATOM   1196 C CB  . SER A 1 165 ? -7.23003  30.11397 30.49595  1.000 34.12460  ? 161 SER H CB  1 
ATOM   1197 O OG  . SER A 1 165 ? -6.37823  31.22766 30.31797  1.000 43.50998  ? 161 SER H OG  1 
ATOM   1198 N N   . GLY A 1 166 ? -6.94245  26.73341 30.77867  1.000 22.70185  ? 162 GLY H N   1 
ATOM   1199 C CA  . GLY A 1 166 ? -7.66442  25.55605 31.20972  1.000 27.28165  ? 162 GLY H CA  1 
ATOM   1200 C C   . GLY A 1 166 ? -7.79584  24.47050 30.16860  1.000 24.91563  ? 162 GLY H C   1 
ATOM   1201 O O   . GLY A 1 166 ? -8.50432  23.48434 30.41129  1.000 20.10194  ? 162 GLY H O   1 
ATOM   1202 N N   . VAL A 1 167 ? -7.15328  24.62622 29.01596  1.000 20.29789  ? 163 VAL H N   1 
ATOM   1203 C CA  . VAL A 1 167 ? -7.17455  23.60261 27.97625  1.000 21.50262  ? 163 VAL H CA  1 
ATOM   1204 C C   . VAL A 1 167 ? -6.16275  22.51263 28.31162  1.000 17.52480  ? 163 VAL H C   1 
ATOM   1205 O O   . VAL A 1 167 ? -5.01242  22.80185 28.64170  1.000 22.88279  ? 163 VAL H O   1 
ATOM   1206 C CB  . VAL A 1 167 ? -6.86944  24.22279 26.60009  1.000 23.30643  ? 163 VAL H CB  1 
ATOM   1207 C CG1 . VAL A 1 167 ? -6.74761  23.12010 25.54676  1.000 23.51326  ? 163 VAL H CG1 1 
ATOM   1208 C CG2 . VAL A 1 167 ? -7.93185  25.25536 26.21968  1.000 17.40314  ? 163 VAL H CG2 1 
ATOM   1209 N N   . HIS A 1 168 ? -6.57332  21.24972 28.19189  1.000 16.51154  ? 164 HIS H N   1 
ATOM   1210 C CA  . HIS A 1 168 ? -5.64181  20.12371 28.23997  1.000 18.28629  ? 164 HIS H CA  1 
ATOM   1211 C C   . HIS A 1 168 ? -5.83470  19.27014 26.99393  1.000 19.25561  ? 164 HIS H C   1 
ATOM   1212 O O   . HIS A 1 168 ? -6.86559  18.61130 26.84708  1.000 18.25571  ? 164 HIS H O   1 
ATOM   1213 C CB  . HIS A 1 168 ? -5.86040  19.27062 29.48427  1.000 17.18456  ? 164 HIS H CB  1 
ATOM   1214 C CG  . HIS A 1 168 ? -5.58541  19.99260 30.75959  1.000 25.48765  ? 164 HIS H CG  1 
ATOM   1215 N ND1 . HIS A 1 168 ? -4.30888  20.31514 31.16533  1.000 24.51664  ? 164 HIS H ND1 1 
ATOM   1216 C CD2 . HIS A 1 168 ? -6.41780  20.44000 31.73065  1.000 27.77248  ? 164 HIS H CD2 1 
ATOM   1217 C CE1 . HIS A 1 168 ? -4.36475  20.93330 32.33494  1.000 28.04823  ? 164 HIS H CE1 1 
ATOM   1218 N NE2 . HIS A 1 168 ? -5.63220  21.02406 32.69777  1.000 26.25809  ? 164 HIS H NE2 1 
ATOM   1219 N N   . THR A 1 169 ? -4.85041  19.25059 26.11234  1.000 20.47997  ? 165 THR H N   1 
ATOM   1220 C CA  . THR A 1 169 ? -4.87920  18.33562 24.97498  1.000 19.58196  ? 165 THR H CA  1 
ATOM   1221 C C   . THR A 1 169 ? -3.96883  17.16580 25.31982  1.000 17.09888  ? 165 THR H C   1 
ATOM   1222 O O   . THR A 1 169 ? -2.75417  17.33247 25.45670  1.000 21.26802  ? 165 THR H O   1 
ATOM   1223 C CB  . THR A 1 169 ? -4.47074  19.04586 23.68828  1.000 18.63708  ? 165 THR H CB  1 
ATOM   1224 O OG1 . THR A 1 169 ? -5.40799  20.09648 23.43011  1.000 21.56745  ? 165 THR H OG1 1 
ATOM   1225 C CG2 . THR A 1 169 ? -4.49482  18.07765 22.49712  1.000 21.21817  ? 165 THR H CG2 1 
ATOM   1226 N N   . PHE A 1 170 ? -4.56107  15.98668 25.49032  1.000 16.62013  ? 166 PHE H N   1 
ATOM   1227 C CA  . PHE A 1 170 ? -3.79207  14.85172 25.97381  1.000 16.73640  ? 166 PHE H CA  1 
ATOM   1228 C C   . PHE A 1 170 ? -2.91630  14.25944 24.87009  1.000 23.49964  ? 166 PHE H C   1 
ATOM   1229 O O   . PHE A 1 170 ? -3.29322  14.27922 23.69364  1.000 18.98828  ? 166 PHE H O   1 
ATOM   1230 C CB  . PHE A 1 170 ? -4.72898  13.77290 26.50876  1.000 16.66726  ? 166 PHE H CB  1 
ATOM   1231 C CG  . PHE A 1 170 ? -5.34679  14.13414 27.82955  1.000 16.99692  ? 166 PHE H CG  1 
ATOM   1232 C CD1 . PHE A 1 170 ? -4.68840  13.84815 29.01313  1.000 17.56515  ? 166 PHE H CD1 1 
ATOM   1233 C CD2 . PHE A 1 170 ? -6.57418  14.78184 27.88119  1.000 20.25721  ? 166 PHE H CD2 1 
ATOM   1234 C CE1 . PHE A 1 170 ? -5.23942  14.21406 30.23656  1.000 18.45845  ? 166 PHE H CE1 1 
ATOM   1235 C CE2 . PHE A 1 170 ? -7.13351  15.15399 29.09429  1.000 21.37712  ? 166 PHE H CE2 1 
ATOM   1236 C CZ  . PHE A 1 170 ? -6.46184  14.86659 30.27963  1.000 18.05908  ? 166 PHE H CZ  1 
ATOM   1237 N N   . PRO A 1 171 ? -1.75591  13.71159 25.24032  1.000 21.43024  ? 167 PRO H N   1 
ATOM   1238 C CA  . PRO A 1 171 ? -0.96541  12.93105 24.28522  1.000 22.81193  ? 167 PRO H CA  1 
ATOM   1239 C C   . PRO A 1 171 ? -1.79613  11.79627 23.71692  1.000 22.70461  ? 167 PRO H C   1 
ATOM   1240 O O   . PRO A 1 171 ? -2.58841  11.16085 24.42154  1.000 18.96782  ? 167 PRO H O   1 
ATOM   1241 C CB  . PRO A 1 171 ? 0.20069   12.39585 25.12516  1.000 19.19959  ? 167 PRO H CB  1 
ATOM   1242 C CG  . PRO A 1 171 ? 0.22290   13.21907 26.36088  1.000 24.73629  ? 167 PRO H CG  1 
ATOM   1243 C CD  . PRO A 1 171 ? -1.17733  13.69079 26.59966  1.000 20.51972  ? 167 PRO H CD  1 
ATOM   1244 N N   . ALA A 1 172 ? -1.61337  11.55448 22.42596  1.000 19.44641  ? 168 ALA H N   1 
ATOM   1245 C CA  . ALA A 1 172 ? -2.35561  10.49827 21.75798  1.000 23.37973  ? 168 ALA H CA  1 
ATOM   1246 C C   . ALA A 1 172 ? -1.90248  9.14440  22.27257  1.000 21.19468  ? 168 ALA H C   1 
ATOM   1247 O O   . ALA A 1 172 ? -0.76247  8.97330  22.71010  1.000 20.87441  ? 168 ALA H O   1 
ATOM   1248 C CB  . ALA A 1 172 ? -2.15093  10.57809 20.23655  1.000 18.48440  ? 168 ALA H CB  1 
ATOM   1249 N N   . VAL A 1 173 ? -2.80946  8.17396  22.22876  1.000 16.62902  ? 169 VAL H N   1 
ATOM   1250 C CA  . VAL A 1 173 ? -2.48930  6.80159  22.58862  1.000 19.15212  ? 169 VAL H CA  1 
ATOM   1251 C C   . VAL A 1 173 ? -2.64497  5.95475  21.33288  1.000 24.40072  ? 169 VAL H C   1 
ATOM   1252 O O   . VAL A 1 173 ? -3.51738  6.22097  20.49436  1.000 18.53985  ? 169 VAL H O   1 
ATOM   1253 C CB  . VAL A 1 173 ? -3.37360  6.27515  23.74007  1.000 25.28706  ? 169 VAL H CB  1 
ATOM   1254 C CG1 . VAL A 1 173 ? -3.21099  7.15163  24.97892  1.000 26.85867  ? 169 VAL H CG1 1 
ATOM   1255 C CG2 . VAL A 1 173 ? -4.82670  6.23453  23.33335  1.000 22.89653  ? 169 VAL H CG2 1 
ATOM   1256 N N   . LEU A 1 174 ? -1.76365  4.97641  21.17396  1.000 18.93166  ? 170 LEU H N   1 
ATOM   1257 C CA  . LEU A 1 174 ? -1.89326  4.03271  20.07439  1.000 18.56907  ? 170 LEU H CA  1 
ATOM   1258 C C   . LEU A 1 174 ? -2.90288  2.97425  20.48203  1.000 19.92135  ? 170 LEU H C   1 
ATOM   1259 O O   . LEU A 1 174 ? -2.74994  2.32880  21.52444  1.000 16.48388  ? 170 LEU H O   1 
ATOM   1260 C CB  . LEU A 1 174 ? -0.54732  3.40270  19.74238  1.000 23.96196  ? 170 LEU H CB  1 
ATOM   1261 C CG  . LEU A 1 174 ? -0.52586  2.42722  18.56932  1.000 17.82007  ? 170 LEU H CG  1 
ATOM   1262 C CD1 . LEU A 1 174 ? -0.85960  3.12786  17.27884  1.000 19.37113  ? 170 LEU H CD1 1 
ATOM   1263 C CD2 . LEU A 1 174 ? 0.85766   1.81410  18.47555  1.000 27.89662  ? 170 LEU H CD2 1 
ATOM   1264 N N   . GLN A 1 175 ? -3.93914  2.81182  19.68193  1.000 18.62827  ? 171 GLN H N   1 
ATOM   1265 C CA  . GLN A 1 175 ? -4.96083  1.81862  19.96184  1.000 23.69595  ? 171 GLN H CA  1 
ATOM   1266 C C   . GLN A 1 175 ? -4.54293  0.45989  19.39928  1.000 22.79827  ? 171 GLN H C   1 
ATOM   1267 O O   . GLN A 1 175 ? -3.62945  0.34739  18.57901  1.000 17.70871  ? 171 GLN H O   1 
ATOM   1268 C CB  . GLN A 1 175 ? -6.30509  2.27779  19.38737  1.000 21.35455  ? 171 GLN H CB  1 
ATOM   1269 C CG  . GLN A 1 175 ? -6.76352  3.63331  19.95578  1.000 25.38367  ? 171 GLN H CG  1 
ATOM   1270 C CD  . GLN A 1 175 ? -7.95402  4.21470  19.21159  1.000 29.18525  ? 171 GLN H CD  1 
ATOM   1271 O OE1 . GLN A 1 175 ? -9.03738  4.36782  19.77873  1.000 35.14696  ? 171 GLN H OE1 1 
ATOM   1272 N NE2 . GLN A 1 175 ? -7.76217  4.54052  17.93144  1.000 25.09272  ? 171 GLN H NE2 1 
ATOM   1273 N N   . SER A 1 176 ? -5.22986  -0.59209 19.85407  1.000 22.87947  ? 172 SER H N   1 
ATOM   1274 C CA  . SER A 1 176 ? -4.89275  -1.93363 19.38631  1.000 22.73619  ? 172 SER H CA  1 
ATOM   1275 C C   . SER A 1 176 ? -5.11101  -2.07663 17.88517  1.000 25.45959  ? 172 SER H C   1 
ATOM   1276 O O   . SER A 1 176 ? -4.50495  -2.94944 17.25262  1.000 24.78454  ? 172 SER H O   1 
ATOM   1277 C CB  . SER A 1 176 ? -5.70911  -2.97513 20.16933  1.000 27.16055  ? 172 SER H CB  1 
ATOM   1278 O OG  . SER A 1 176 ? -7.09101  -2.82656 19.90328  1.000 29.37261  ? 172 SER H OG  1 
ATOM   1279 N N   . SER A 1 177 ? -5.92332  -1.20179 17.29478  1.000 20.21898  ? 173 SER H N   1 
ATOM   1280 C CA  . SER A 1 177 ? -6.10922  -1.12975 15.85452  1.000 24.45789  ? 173 SER H CA  1 
ATOM   1281 C C   . SER A 1 177 ? -4.89526  -0.56800 15.13117  1.000 27.74033  ? 173 SER H C   1 
ATOM   1282 O O   . SER A 1 177 ? -4.85214  -0.62162 13.89848  1.000 25.63136  ? 173 SER H O   1 
ATOM   1283 C CB  . SER A 1 177 ? -7.31963  -0.24793 15.54555  1.000 26.47273  ? 173 SER H CB  1 
ATOM   1284 O OG  . SER A 1 177 ? -7.10004  1.05610  16.06076  1.000 23.11983  ? 173 SER H OG  1 
ATOM   1285 N N   . GLY A 1 178 ? -3.91743  -0.02523 15.85489  1.000 26.29337  ? 174 GLY H N   1 
ATOM   1286 C CA  . GLY A 1 178 ? -2.83016  0.69328  15.21989  1.000 24.18455  ? 174 GLY H CA  1 
ATOM   1287 C C   . GLY A 1 178 ? -3.15766  2.11438  14.80934  1.000 25.60374  ? 174 GLY H C   1 
ATOM   1288 O O   . GLY A 1 178 ? -2.32344  2.76245  14.16801  1.000 20.59592  ? 174 GLY H O   1 
ATOM   1289 N N   . LEU A 1 179 ? -4.33742  2.62173  15.15368  1.000 18.27999  ? 175 LEU H N   1 
ATOM   1290 C CA  . LEU A 1 179 ? -4.70105  4.01113  14.91318  1.000 16.61178  ? 175 LEU H CA  1 
ATOM   1291 C C   . LEU A 1 179 ? -4.58556  4.78404  16.22195  1.000 20.15125  ? 175 LEU H C   1 
ATOM   1292 O O   . LEU A 1 179 ? -4.69882  4.20831  17.30398  1.000 21.83835  ? 175 LEU H O   1 
ATOM   1293 C CB  . LEU A 1 179 ? -6.13143  4.11692  14.37410  1.000 18.29715  ? 175 LEU H CB  1 
ATOM   1294 C CG  . LEU A 1 179 ? -6.45734  3.21796  13.16989  1.000 23.56086  ? 175 LEU H CG  1 
ATOM   1295 C CD1 . LEU A 1 179 ? -7.96970  3.15551  12.86904  1.000 21.81138  ? 175 LEU H CD1 1 
ATOM   1296 C CD2 . LEU A 1 179 ? -5.68989  3.70216  11.96621  1.000 23.09180  ? 175 LEU H CD2 1 
ATOM   1297 N N   . TYR A 1 180 ? -4.37290  6.09061  16.11681  1.000 16.03796  ? 176 TYR H N   1 
ATOM   1298 C CA  . TYR A 1 180 ? -4.24057  6.94109  17.29202  1.000 16.51322  ? 176 TYR H CA  1 
ATOM   1299 C C   . TYR A 1 180 ? -5.58921  7.51107  17.72597  1.000 16.12361  ? 176 TYR H C   1 
ATOM   1300 O O   . TYR A 1 180 ? -6.53399  7.64041  16.93461  1.000 15.96591  ? 176 TYR H O   1 
ATOM   1301 C CB  . TYR A 1 180 ? -3.26085  8.08502  17.01585  1.000 13.19834  ? 176 TYR H CB  1 
ATOM   1302 C CG  . TYR A 1 180 ? -1.84647  7.57768  16.90304  1.000 17.04096  ? 176 TYR H CG  1 
ATOM   1303 C CD1 . TYR A 1 180 ? -1.10994  7.26548  18.03321  1.000 17.73111  ? 176 TYR H CD1 1 
ATOM   1304 C CD2 . TYR A 1 180 ? -1.26381  7.37132  15.65848  1.000 21.63300  ? 176 TYR H CD2 1 
ATOM   1305 C CE1 . TYR A 1 180 ? 0.17770   6.77976  17.92862  1.000 19.74574  ? 176 TYR H CE1 1 
ATOM   1306 C CE2 . TYR A 1 180 ? 0.02840   6.88838  15.54359  1.000 22.26409  ? 176 TYR H CE2 1 
ATOM   1307 C CZ  . TYR A 1 180 ? 0.73477   6.58857  16.66942  1.000 21.31251  ? 176 TYR H CZ  1 
ATOM   1308 O OH  . TYR A 1 180 ? 2.01136   6.10354  16.54239  1.000 25.57438  ? 176 TYR H OH  1 
ATOM   1309 N N   . SER A 1 181 ? -5.66167  7.86588  19.00510  1.000 17.90655  ? 177 SER H N   1 
ATOM   1310 C CA  . SER A 1 181 ? -6.81143  8.57656  19.54149  1.000 17.37284  ? 177 SER H CA  1 
ATOM   1311 C C   . SER A 1 181 ? -6.33592  9.56019  20.59926  1.000 21.44423  ? 177 SER H C   1 
ATOM   1312 O O   . SER A 1 181 ? -5.40191  9.27552  21.35258  1.000 20.93278  ? 177 SER H O   1 
ATOM   1313 C CB  . SER A 1 181 ? -7.83320  7.61248  20.14470  1.000 23.32889  ? 177 SER H CB  1 
ATOM   1314 O OG  . SER A 1 181 ? -8.94174  8.32145  20.65212  1.000 30.52414  ? 177 SER H OG  1 
ATOM   1315 N N   . LEU A 1 182 ? -6.99845  10.71167 20.67067  1.000 18.50600  ? 178 LEU H N   1 
ATOM   1316 C CA  . LEU A 1 182 ? -6.74477  11.60946 21.78777  1.000 22.46930  ? 178 LEU H CA  1 
ATOM   1317 C C   . LEU A 1 182 ? -8.01676  12.37155 22.13678  1.000 18.75245  ? 178 LEU H C   1 
ATOM   1318 O O   . LEU A 1 182 ? -9.00076  12.36481 21.39692  1.000 18.80831  ? 178 LEU H O   1 
ATOM   1319 C CB  . LEU A 1 182 ? -5.57700  12.56038 21.47736  1.000 13.41245  ? 178 LEU H CB  1 
ATOM   1320 C CG  . LEU A 1 182 ? -5.66562  13.65191 20.41440  1.000 21.75254  ? 178 LEU H CG  1 
ATOM   1321 C CD1 . LEU A 1 182 ? -6.55780  14.81924 20.86730  1.000 23.01244  ? 178 LEU H CD1 1 
ATOM   1322 C CD2 . LEU A 1 182 ? -4.24653  14.17210 20.17094  1.000 24.67688  ? 178 LEU H CD2 1 
ATOM   1323 N N   . SER A 1 183 ? -7.97856  13.02713 23.29200  1.000 20.89853  ? 179 SER H N   1 
ATOM   1324 C CA  . SER A 1 183 ? -8.99891  13.96679 23.71260  1.000 15.43546  ? 179 SER H CA  1 
ATOM   1325 C C   . SER A 1 183 ? -8.34455  15.30294 24.03068  1.000 17.56202  ? 179 SER H C   1 
ATOM   1326 O O   . SER A 1 183 ? -7.18065  15.36451 24.43651  1.000 15.89205  ? 179 SER H O   1 
ATOM   1327 C CB  . SER A 1 183 ? -9.76730  13.47368 24.94711  1.000 16.85569  ? 179 SER H CB  1 
ATOM   1328 O OG  . SER A 1 183 ? -10.69796 12.44782 24.58858  1.000 27.07673  ? 179 SER H OG  1 
ATOM   1329 N N   . SER A 1 184 ? -9.10932  16.37039 23.83470  1.000 20.43160  ? 180 SER H N   1 
ATOM   1330 C CA  . SER A 1 184 ? -8.75234  17.70630 24.29328  1.000 19.16600  ? 180 SER H CA  1 
ATOM   1331 C C   . SER A 1 184 ? -9.93873  18.23037 25.08316  1.000 16.49543  ? 180 SER H C   1 
ATOM   1332 O O   . SER A 1 184 ? -11.08263 18.13895 24.61496  1.000 19.20509  ? 180 SER H O   1 
ATOM   1333 C CB  . SER A 1 184 ? -8.42606  18.63779 23.12434  1.000 15.58682  ? 180 SER H CB  1 
ATOM   1334 O OG  . SER A 1 184 ? -8.18654  19.97580 23.56347  1.000 18.24563  ? 180 SER H OG  1 
ATOM   1335 N N   . VAL A 1 185 ? -9.67219  18.72962 26.28854  1.000 16.83148  ? 181 VAL H N   1 
ATOM   1336 C CA  . VAL A 1 185 ? -10.71746 19.17389 27.20160  1.000 15.66717  ? 181 VAL H CA  1 
ATOM   1337 C C   . VAL A 1 185 ? -10.37103 20.57803 27.66833  1.000 21.11704  ? 181 VAL H C   1 
ATOM   1338 O O   . VAL A 1 185 ? -9.21824  21.00869 27.62188  1.000 18.59042  ? 181 VAL H O   1 
ATOM   1339 C CB  . VAL A 1 185 ? -10.89825 18.24279 28.42780  1.000 16.56367  ? 181 VAL H CB  1 
ATOM   1340 C CG1 . VAL A 1 185 ? -11.35857 16.85458 28.00727  1.000 20.19185  ? 181 VAL H CG1 1 
ATOM   1341 C CG2 . VAL A 1 185 ? -9.61452  18.17475 29.27493  1.000 16.60485  ? 181 VAL H CG2 1 
ATOM   1342 N N   . VAL A 1 186 ? -11.39271 21.29272 28.12835  1.000 19.99839  ? 182 VAL H N   1 
ATOM   1343 C CA  . VAL A 1 186 ? -11.20871 22.60402 28.72999  1.000 19.91886  ? 182 VAL H CA  1 
ATOM   1344 C C   . VAL A 1 186 ? -12.22051 22.74750 29.86110  1.000 18.43619  ? 182 VAL H C   1 
ATOM   1345 O O   . VAL A 1 186 ? -13.34784 22.24615 29.77204  1.000 21.26011  ? 182 VAL H O   1 
ATOM   1346 C CB  . VAL A 1 186 ? -11.35700 23.73074 27.67795  1.000 24.47273  ? 182 VAL H CB  1 
ATOM   1347 C CG1 . VAL A 1 186 ? -12.72385 23.68282 27.01869  1.000 21.61844  ? 182 VAL H CG1 1 
ATOM   1348 C CG2 . VAL A 1 186 ? -11.13332 25.10297 28.30105  1.000 20.50117  ? 182 VAL H CG2 1 
ATOM   1349 N N   . THR A 1 187 ? -11.81701 23.41661 30.93267  1.000 22.54455  ? 183 THR H N   1 
ATOM   1350 C CA  . THR A 1 187 ? -12.73344 23.75372 32.01895  1.000 20.06361  ? 183 THR H CA  1 
ATOM   1351 C C   . THR A 1 187 ? -13.10020 25.23173 31.92459  1.000 23.09010  ? 183 THR H C   1 
ATOM   1352 O O   . THR A 1 187 ? -12.22459 26.09068 31.75567  1.000 24.40323  ? 183 THR H O   1 
ATOM   1353 C CB  . THR A 1 187 ? -12.11447 23.43767 33.37722  1.000 19.49183  ? 183 THR H CB  1 
ATOM   1354 O OG1 . THR A 1 187 ? -10.83318 24.05985 33.46572  1.000 23.87588  ? 183 THR H OG1 1 
ATOM   1355 C CG2 . THR A 1 187 ? -11.95322 21.93127 33.54417  1.000 22.04746  ? 183 THR H CG2 1 
ATOM   1356 N N   . VAL A 1 188 ? -14.39394 25.51332 32.01890  1.000 21.91304  ? 184 VAL H N   1 
ATOM   1357 C CA  . VAL A 1 188 ? -14.94281 26.85792 31.85468  1.000 26.00253  ? 184 VAL H CA  1 
ATOM   1358 C C   . VAL A 1 188 ? -15.97554 27.10060 32.94652  1.000 32.78465  ? 184 VAL H C   1 
ATOM   1359 O O   . VAL A 1 188 ? -16.48326 26.15492 33.56320  1.000 25.19940  ? 184 VAL H O   1 
ATOM   1360 C CB  . VAL A 1 188 ? -15.59864 27.03868 30.47211  1.000 27.55888  ? 184 VAL H CB  1 
ATOM   1361 C CG1 . VAL A 1 188 ? -14.61017 26.69484 29.34836  1.000 27.63451  ? 184 VAL H CG1 1 
ATOM   1362 C CG2 . VAL A 1 188 ? -16.84095 26.17761 30.35979  1.000 28.58333  ? 184 VAL H CG2 1 
ATOM   1363 N N   . PRO A 1 189 ? -16.29405 28.36393 33.21973  1.000 26.30744  ? 185 PRO H N   1 
ATOM   1364 C CA  . PRO A 1 189 ? -17.37213 28.64445 34.17901  1.000 32.55493  ? 185 PRO H CA  1 
ATOM   1365 C C   . PRO A 1 189 ? -18.69494 28.09742 33.66785  1.000 29.38199  ? 185 PRO H C   1 
ATOM   1366 O O   . PRO A 1 189 ? -19.04616 28.27648 32.49855  1.000 27.42732  ? 185 PRO H O   1 
ATOM   1367 C CB  . PRO A 1 189 ? -17.38267 30.17569 34.26415  1.000 31.73950  ? 185 PRO H CB  1 
ATOM   1368 C CG  . PRO A 1 189 ? -15.99515 30.57664 33.91952  1.000 31.24769  ? 185 PRO H CG  1 
ATOM   1369 C CD  . PRO A 1 189 ? -15.57188 29.59078 32.83920  1.000 29.51162  ? 185 PRO H CD  1 
ATOM   1370 N N   . SER A 1 190 ? -19.42309 27.40584 34.55377  1.000 24.74025  ? 186 SER H N   1 
ATOM   1371 C CA  . SER A 1 190 ? -20.71571 26.85308 34.16667  1.000 26.78702  ? 186 SER H CA  1 
ATOM   1372 C C   . SER A 1 190 ? -21.66542 27.94042 33.71390  1.000 33.77926  ? 186 SER H C   1 
ATOM   1373 O O   . SER A 1 190 ? -22.46701 27.72204 32.79770  1.000 33.34023  ? 186 SER H O   1 
ATOM   1374 C CB  . SER A 1 190 ? -21.35160 26.08796 35.32811  1.000 38.48001  ? 186 SER H CB  1 
ATOM   1375 O OG  . SER A 1 190 ? -20.41389 25.23343 35.93724  1.000 48.60497  ? 186 SER H OG  1 
ATOM   1376 N N   . SER A 1 191 ? -21.59291 29.11604 34.34079  1.000 33.10541  ? 187 SER H N   1 
ATOM   1377 C CA  . SER A 1 191 ? -22.49385 30.19920 33.96630  1.000 34.81210  ? 187 SER H CA  1 
ATOM   1378 C C   . SER A 1 191 ? -22.31810 30.61741 32.51239  1.000 38.11204  ? 187 SER H C   1 
ATOM   1379 O O   . SER A 1 191 ? -23.21677 31.25073 31.94924  1.000 43.69679  ? 187 SER H O   1 
ATOM   1380 C CB  . SER A 1 191 ? -22.28681 31.39290 34.89489  1.000 33.50635  ? 187 SER H CB  1 
ATOM   1381 O OG  . SER A 1 191 ? -20.95400 31.86586 34.83475  1.000 31.62034  ? 187 SER H OG  1 
ATOM   1382 N N   . SER A 1 192 ? -21.20333 30.24861 31.87861  1.000 37.71143  ? 188 SER H N   1 
ATOM   1383 C CA  . SER A 1 192 ? -20.95889 30.61777 30.49111  1.000 31.79249  ? 188 SER H CA  1 
ATOM   1384 C C   . SER A 1 192 ? -21.61525 29.68070 29.48118  1.000 37.07136  ? 188 SER H C   1 
ATOM   1385 O O   . SER A 1 192 ? -21.59953 29.98601 28.28508  1.000 43.79321  ? 188 SER H O   1 
ATOM   1386 C CB  . SER A 1 192 ? -19.45018 30.67064 30.22016  1.000 37.12184  ? 188 SER H CB  1 
ATOM   1387 O OG  . SER A 1 192 ? -18.87593 29.36747 30.20857  1.000 31.85863  ? 188 SER H OG  1 
ATOM   1388 N N   . LEU A 1 193 ? -22.20104 28.56214 29.91800  1.000 37.64375  ? 189 LEU H N   1 
ATOM   1389 C CA  . LEU A 1 193 ? -22.60906 27.54064 28.95606  1.000 39.61091  ? 189 LEU H CA  1 
ATOM   1390 C C   . LEU A 1 193 ? -23.73841 28.02342 28.04885  1.000 45.02227  ? 189 LEU H C   1 
ATOM   1391 O O   . LEU A 1 193 ? -23.77344 27.66837 26.86471  1.000 40.34324  ? 189 LEU H O   1 
ATOM   1392 C CB  . LEU A 1 193 ? -23.00481 26.25984 29.68832  1.000 34.88630  ? 189 LEU H CB  1 
ATOM   1393 C CG  . LEU A 1 193 ? -21.85213 25.53409 30.39390  1.000 38.31424  ? 189 LEU H CG  1 
ATOM   1394 C CD1 . LEU A 1 193 ? -22.34156 24.24576 31.06262  1.000 32.61515  ? 189 LEU H CD1 1 
ATOM   1395 C CD2 . LEU A 1 193 ? -20.71656 25.24528 29.41851  1.000 26.78050  ? 189 LEU H CD2 1 
ATOM   1396 N N   . GLY A 1 194 ? -24.65934 28.84164 28.56734  1.000 43.59663  ? 190 GLY H N   1 
ATOM   1397 C CA  . GLY A 1 194 ? -25.69687 29.40263 27.71242  1.000 51.15707  ? 190 GLY H CA  1 
ATOM   1398 C C   . GLY A 1 194 ? -25.24872 30.55765 26.84292  1.000 41.25119  ? 190 GLY H C   1 
ATOM   1399 O O   . GLY A 1 194 ? -25.86790 30.81665 25.80628  1.000 50.43466  ? 190 GLY H O   1 
ATOM   1400 N N   . THR A 1 195 ? -24.18197 31.24782 27.23540  1.000 49.29778  ? 191 THR H N   1 
ATOM   1401 C CA  . THR A 1 195 ? -23.73496 32.45086 26.54460  1.000 52.18944  ? 191 THR H CA  1 
ATOM   1402 C C   . THR A 1 195 ? -22.65794 32.15645 25.50870  1.000 48.71811  ? 191 THR H C   1 
ATOM   1403 O O   . THR A 1 195 ? -22.78215 32.54783 24.34569  1.000 52.65165  ? 191 THR H O   1 
ATOM   1404 C CB  . THR A 1 195 ? -23.19318 33.47063 27.55780  1.000 49.69693  ? 191 THR H CB  1 
ATOM   1405 O OG1 . THR A 1 195 ? -24.14220 33.64840 28.61337  1.000 59.82183  ? 191 THR H OG1 1 
ATOM   1406 C CG2 . THR A 1 195 ? -22.92716 34.81094 26.88682  1.000 58.46528  ? 191 THR H CG2 1 
ATOM   1407 N N   . GLN A 1 196 ? -21.60933 31.45484 25.91917  1.000 40.40076  ? 192 GLN H N   1 
ATOM   1408 C CA  . GLN A 1 196 ? -20.36650 31.39120 25.16994  1.000 38.61020  ? 192 GLN H CA  1 
ATOM   1409 C C   . GLN A 1 196 ? -20.34687 30.17168 24.25517  1.000 35.09846  ? 192 GLN H C   1 
ATOM   1410 O O   . GLN A 1 196 ? -20.64221 29.05417 24.68968  1.000 30.70806  ? 192 GLN H O   1 
ATOM   1411 C CB  . GLN A 1 196 ? -19.18480 31.34879 26.14005  1.000 38.84127  ? 192 GLN H CB  1 
ATOM   1412 C CG  . GLN A 1 196 ? -17.85422 31.16300 25.47495  1.000 32.83345  ? 192 GLN H CG  1 
ATOM   1413 C CD  . GLN A 1 196 ? -17.48891 32.33631 24.61122  1.000 39.87111  ? 192 GLN H CD  1 
ATOM   1414 O OE1 . GLN A 1 196 ? -17.43336 33.46909 25.08834  1.000 42.77903  ? 192 GLN H OE1 1 
ATOM   1415 N NE2 . GLN A 1 196 ? -17.25408 32.08173 23.32209  1.000 31.84773  ? 192 GLN H NE2 1 
ATOM   1416 N N   . THR A 1 197 ? -20.00387 30.39217 22.98821  1.000 33.48614  ? 193 THR H N   1 
ATOM   1417 C CA  . THR A 1 197 ? -19.80657 29.29361 22.05503  1.000 29.68898  ? 193 THR H CA  1 
ATOM   1418 C C   . THR A 1 197 ? -18.41303 28.70259 22.22625  1.000 25.33565  ? 193 THR H C   1 
ATOM   1419 O O   . THR A 1 197 ? -17.42940 29.42987 22.38194  1.000 24.90773  ? 193 THR H O   1 
ATOM   1420 C CB  . THR A 1 197 ? -20.00462 29.77232 20.61501  1.000 29.37111  ? 193 THR H CB  1 
ATOM   1421 O OG1 . THR A 1 197 ? -21.36189 30.18277 20.45218  1.000 33.66115  ? 193 THR H OG1 1 
ATOM   1422 C CG2 . THR A 1 197 ? -19.72115 28.65424 19.63810  1.000 31.22928  ? 193 THR H CG2 1 
ATOM   1423 N N   . TYR A 1 198 ? -18.34507 27.37132 22.21627  1.000 24.35431  ? 194 TYR H N   1 
ATOM   1424 C CA  . TYR A 1 198 ? -17.10462 26.61756 22.35194  1.000 23.51394  ? 194 TYR H CA  1 
ATOM   1425 C C   . TYR A 1 198 ? -16.96995 25.70084 21.14754  1.000 24.31140  ? 194 TYR H C   1 
ATOM   1426 O O   . TYR A 1 198 ? -17.82212 24.83444 20.92285  1.000 21.77457  ? 194 TYR H O   1 
ATOM   1427 C CB  . TYR A 1 198 ? -17.08430 25.80026 23.64189  1.000 22.31342  ? 194 TYR H CB  1 
ATOM   1428 C CG  . TYR A 1 198 ? -17.09253 26.67785 24.85959  1.000 22.35433  ? 194 TYR H CG  1 
ATOM   1429 C CD1 . TYR A 1 198 ? -15.96246 27.38380 25.22503  1.000 22.69646  ? 194 TYR H CD1 1 
ATOM   1430 C CD2 . TYR A 1 198 ? -18.23023 26.80815 25.63698  1.000 26.08063  ? 194 TYR H CD2 1 
ATOM   1431 C CE1 . TYR A 1 198 ? -15.96658 28.20899 26.33634  1.000 29.06142  ? 194 TYR H CE1 1 
ATOM   1432 C CE2 . TYR A 1 198 ? -18.23809 27.62224 26.75715  1.000 27.79884  ? 194 TYR H CE2 1 
ATOM   1433 C CZ  . TYR A 1 198 ? -17.10520 28.32589 27.09383  1.000 23.59359  ? 194 TYR H CZ  1 
ATOM   1434 O OH  . TYR A 1 198 ? -17.10474 29.15161 28.20165  1.000 24.97335  ? 194 TYR H OH  1 
ATOM   1435 N N   . ILE A 1 199 ? -15.90718 25.89751 20.38046  1.000 21.17507  ? 195 ILE H N   1 
ATOM   1436 C CA  . ILE A 1 199 ? -15.65611 25.14201 19.15969  1.000 25.27989  ? 195 ILE H CA  1 
ATOM   1437 C C   . ILE A 1 199 ? -14.23878 24.60274 19.23501  1.000 20.06221  ? 195 ILE H C   1 
ATOM   1438 O O   . ILE A 1 199 ? -13.29154 25.36845 19.44720  1.000 19.25021  ? 195 ILE H O   1 
ATOM   1439 C CB  . ILE A 1 199 ? -15.83120 26.01965 17.90306  1.000 23.63241  ? 195 ILE H CB  1 
ATOM   1440 C CG1 . ILE A 1 199 ? -17.26016 26.54797 17.79093  1.000 21.59033  ? 195 ILE H CG1 1 
ATOM   1441 C CG2 . ILE A 1 199 ? -15.41729 25.25376 16.64659  1.000 20.61419  ? 195 ILE H CG2 1 
ATOM   1442 C CD1 . ILE A 1 199 ? -17.37039 27.75385 16.84724  1.000 29.04129  ? 195 ILE H CD1 1 
ATOM   1443 N N   . CYS A 1 200 ? -14.07840 23.29092 19.06637  1.000 20.72687  ? 196 CYS H N   1 
ATOM   1444 C CA  . CYS A 1 200 ? -12.73123 22.75528 18.98083  1.000 17.64655  ? 196 CYS H CA  1 
ATOM   1445 C C   . CYS A 1 200 ? -12.32887 22.68632 17.50970  1.000 22.81800  ? 196 CYS H C   1 
ATOM   1446 O O   . CYS A 1 200 ? -13.13149 22.29857 16.65374  1.000 22.49810  ? 196 CYS H O   1 
ATOM   1447 C CB  . CYS A 1 200 ? -12.62917 21.39624 19.67202  1.000 23.87331  ? 196 CYS H CB  1 
ATOM   1448 S SG  . CYS A 1 200 ? -13.37385 19.99286 18.84008  1.000 33.47742  ? 196 CYS H SG  1 
ATOM   1449 N N   . ASN A 1 201 ? -11.10599 23.12058 17.21957  1.000 21.11994  ? 197 ASN H N   1 
ATOM   1450 C CA  . ASN A 1 201 ? -10.56138 23.14681 15.86468  1.000 21.59835  ? 197 ASN H CA  1 
ATOM   1451 C C   . ASN A 1 201 ? -9.51884  22.04185 15.77362  1.000 22.54159  ? 197 ASN H C   1 
ATOM   1452 O O   . ASN A 1 201 ? -8.43075  22.16001 16.34281  1.000 22.01882  ? 197 ASN H O   1 
ATOM   1453 C CB  . ASN A 1 201 ? -9.95974  24.51195 15.56197  1.000 23.26034  ? 197 ASN H CB  1 
ATOM   1454 C CG  . ASN A 1 201 ? -10.79915 25.64870 16.12829  1.000 32.32994  ? 197 ASN H CG  1 
ATOM   1455 O OD1 . ASN A 1 201 ? -10.41888 26.29098 17.11444  1.000 29.38411  ? 197 ASN H OD1 1 
ATOM   1456 N ND2 . ASN A 1 201 ? -11.95035 25.90312 15.50445  1.000 21.24799  ? 197 ASN H ND2 1 
ATOM   1457 N N   . VAL A 1 202 ? -9.85350  20.96159 15.07837  1.000 19.82237  ? 198 VAL H N   1 
ATOM   1458 C CA  . VAL A 1 202 ? -8.97361  19.80299 14.97702  1.000 18.11671  ? 198 VAL H CA  1 
ATOM   1459 C C   . VAL A 1 202 ? -8.33950  19.82297 13.59898  1.000 23.36452  ? 198 VAL H C   1 
ATOM   1460 O O   . VAL A 1 202 ? -9.05281  19.84198 12.59005  1.000 21.56043  ? 198 VAL H O   1 
ATOM   1461 C CB  . VAL A 1 202 ? -9.74497  18.49987 15.21703  1.000 18.59277  ? 198 VAL H CB  1 
ATOM   1462 C CG1 . VAL A 1 202 ? -8.81815  17.29290 15.08687  1.000 21.33439  ? 198 VAL H CG1 1 
ATOM   1463 C CG2 . VAL A 1 202 ? -10.42939 18.54683 16.58090  1.000 18.81560  ? 198 VAL H CG2 1 
ATOM   1464 N N   . ASN A 1 203 ? -7.00651  19.83576 13.55011  1.000 17.69976  ? 199 ASN H N   1 
ATOM   1465 C CA  . ASN A 1 203 ? -6.27741  19.81186 12.28957  1.000 20.53400  ? 199 ASN H CA  1 
ATOM   1466 C C   . ASN A 1 203 ? -5.45306  18.53919 12.19905  1.000 22.83955  ? 199 ASN H C   1 
ATOM   1467 O O   . ASN A 1 203 ? -4.63440  18.26274 13.08154  1.000 22.65716  ? 199 ASN H O   1 
ATOM   1468 C CB  . ASN A 1 203 ? -5.35594  21.02560 12.12277  1.000 23.44832  ? 199 ASN H CB  1 
ATOM   1469 C CG  . ASN A 1 203 ? -4.99180  21.26903 10.65672  1.000 33.11803  ? 199 ASN H CG  1 
ATOM   1470 O OD1 . ASN A 1 203 ? -5.61018  20.70314 9.75880   1.000 31.86841  ? 199 ASN H OD1 1 
ATOM   1471 N ND2 . ASN A 1 203 ? -4.00202  22.11273 10.41605  1.000 37.29307  ? 199 ASN H ND2 1 
ATOM   1472 N N   . HIS A 1 204 ? -5.65791  17.78233 11.12230  1.000 19.54663  ? 200 HIS H N   1 
ATOM   1473 C CA  . HIS A 1 204 ? -4.82899  16.62526 10.77486  1.000 18.56848  ? 200 HIS H CA  1 
ATOM   1474 C C   . HIS A 1 204 ? -4.18684  16.92438 9.42709   1.000 21.30885  ? 200 HIS H C   1 
ATOM   1475 O O   . HIS A 1 204 ? -4.70750  16.54259 8.37618   1.000 19.68114  ? 200 HIS H O   1 
ATOM   1476 C CB  . HIS A 1 204 ? -5.65553  15.34953 10.73689  1.000 22.05774  ? 200 HIS H CB  1 
ATOM   1477 C CG  . HIS A 1 204 ? -4.83568  14.09775 10.65059  1.000 22.21784  ? 200 HIS H CG  1 
ATOM   1478 N ND1 . HIS A 1 204 ? -5.05260  13.12877 9.69191   1.000 20.64513  ? 200 HIS H ND1 1 
ATOM   1479 C CD2 . HIS A 1 204 ? -3.79534  13.66036 11.40045  1.000 17.00228  ? 200 HIS H CD2 1 
ATOM   1480 C CE1 . HIS A 1 204 ? -4.19908  12.13507 9.87468   1.000 21.60537  ? 200 HIS H CE1 1 
ATOM   1481 N NE2 . HIS A 1 204 ? -3.42786  12.43142 10.90897  1.000 17.78296  ? 200 HIS H NE2 1 
ATOM   1482 N N   . LYS A 1 205 ? -3.06183  17.63539 9.46255   1.000 21.15054  ? 201 LYS H N   1 
ATOM   1483 C CA  . LYS A 1 205 ? -2.34499  17.94574 8.22844   1.000 26.67081  ? 201 LYS H CA  1 
ATOM   1484 C C   . LYS A 1 205 ? -1.94677  16.72144 7.40855   1.000 24.60390  ? 201 LYS H C   1 
ATOM   1485 O O   . LYS A 1 205 ? -2.00495  16.80951 6.16796   1.000 23.63323  ? 201 LYS H O   1 
ATOM   1486 C CB  . LYS A 1 205 ? -1.11177  18.80344 8.54809   1.000 31.39572  ? 201 LYS H CB  1 
ATOM   1487 C CG  . LYS A 1 205 ? -1.45166  20.15186 9.19635   1.000 41.82582  ? 201 LYS H CG  1 
ATOM   1488 C CD  . LYS A 1 205 ? -0.53951  21.27411 8.70476   1.000 48.51421  ? 201 LYS H CD  1 
ATOM   1489 C CE  . LYS A 1 205 ? -0.72709  22.55367 9.52123   1.000 52.23666  ? 201 LYS H CE  1 
ATOM   1490 N NZ  . LYS A 1 205 ? -0.08192  22.48257 10.87181  1.000 57.72848  ? 201 LYS H NZ  1 
ATOM   1491 N N   . PRO A 1 206 ? -1.54948  15.57555 7.98891   1.000 22.18203  ? 202 PRO H N   1 
ATOM   1492 C CA  . PRO A 1 206 ? -1.19227  14.43565 7.12519   1.000 22.45610  ? 202 PRO H CA  1 
ATOM   1493 C C   . PRO A 1 206 ? -2.31182  13.96455 6.22051   1.000 25.83625  ? 202 PRO H C   1 
ATOM   1494 O O   . PRO A 1 206 ? -2.02307  13.39355 5.16595   1.000 22.71158  ? 202 PRO H O   1 
ATOM   1495 C CB  . PRO A 1 206 ? -0.78164  13.34280 8.12249   1.000 20.20254  ? 202 PRO H CB  1 
ATOM   1496 C CG  . PRO A 1 206 ? -0.29966  14.10199 9.30652   1.000 16.37149  ? 202 PRO H CG  1 
ATOM   1497 C CD  . PRO A 1 206 ? -1.21366  15.29362 9.39757   1.000 21.68486  ? 202 PRO H CD  1 
ATOM   1498 N N   . SER A 1 207 ? -3.57965  14.17315 6.57284   1.000 20.66710  ? 203 SER H N   1 
ATOM   1499 C CA  . SER A 1 207 ? -4.66415  13.79873 5.66881   1.000 19.68200  ? 203 SER H CA  1 
ATOM   1500 C C   . SER A 1 207 ? -5.33538  15.01455 5.03624   1.000 21.33098  ? 203 SER H C   1 
ATOM   1501 O O   . SER A 1 207 ? -6.37426  14.86666 4.38058   1.000 19.69846  ? 203 SER H O   1 
ATOM   1502 C CB  . SER A 1 207 ? -5.70291  12.93544 6.39769   1.000 18.62738  ? 203 SER H CB  1 
ATOM   1503 O OG  . SER A 1 207 ? -6.42348  13.67929 7.37488   1.000 22.34935  ? 203 SER H OG  1 
ATOM   1504 N N   . ASN A 1 208 ? -4.77388  16.20928 5.23274   1.000 20.85361  ? 204 ASN H N   1 
ATOM   1505 C CA  . ASN A 1 208 ? -5.36632  17.46795 4.75699   1.000 25.09139  ? 204 ASN H CA  1 
ATOM   1506 C C   . ASN A 1 208 ? -6.83114  17.59039 5.17246   1.000 27.28548  ? 204 ASN H C   1 
ATOM   1507 O O   . ASN A 1 208 ? -7.69827  17.95672 4.37818   1.000 26.40980  ? 204 ASN H O   1 
ATOM   1508 C CB  . ASN A 1 208 ? -5.21883  17.61389 3.24024   1.000 23.88864  ? 204 ASN H CB  1 
ATOM   1509 C CG  . ASN A 1 208 ? -3.76199  17.69594 2.80065   1.000 33.17113  ? 204 ASN H CG  1 
ATOM   1510 O OD1 . ASN A 1 208 ? -3.07761  18.69840 3.02754   1.000 40.40845  ? 204 ASN H OD1 1 
ATOM   1511 N ND2 . ASN A 1 208 ? -3.28629  16.63873 2.17270   1.000 27.28250  ? 204 ASN H ND2 1 
ATOM   1512 N N   . THR A 1 209 ? -7.09723  17.29843 6.44768   1.000 20.96612  ? 205 THR H N   1 
ATOM   1513 C CA  . THR A 1 209 ? -8.43169  17.36192 7.02861   1.000 22.18699  ? 205 THR H CA  1 
ATOM   1514 C C   . THR A 1 209 ? -8.41509  18.31615 8.21682   1.000 27.44991  ? 205 THR H C   1 
ATOM   1515 O O   . THR A 1 209 ? -7.50756  18.25510 9.05378   1.000 21.00691  ? 205 THR H O   1 
ATOM   1516 C CB  . THR A 1 209 ? -8.89982  15.97339 7.47914   1.000 27.87503  ? 205 THR H CB  1 
ATOM   1517 O OG1 . THR A 1 209 ? -8.86797  15.07447 6.36257   1.000 34.12579  ? 205 THR H OG1 1 
ATOM   1518 C CG2 . THR A 1 209 ? -10.32088 16.02178 8.03968   1.000 24.67429  ? 205 THR H CG2 1 
ATOM   1519 N N   . LYS A 1 210 ? -9.40701  19.19970 8.27499   1.000 26.41263  ? 206 LYS H N   1 
ATOM   1520 C CA  . LYS A 1 210 ? -9.64493  20.07876 9.41159   1.000 21.25185  ? 206 LYS H CA  1 
ATOM   1521 C C   . LYS A 1 210 ? -11.09876 19.91664 9.81876   1.000 27.76243  ? 206 LYS H C   1 
ATOM   1522 O O   . LYS A 1 210 ? -11.98192 19.86837 8.95892   1.000 25.59184  ? 206 LYS H O   1 
ATOM   1523 C CB  . LYS A 1 210 ? -9.33595  21.56200 9.04947   1.000 21.74408  ? 206 LYS H CB  1 
ATOM   1524 C CG  . LYS A 1 210 ? -9.15388  22.46584 10.25032  1.000 36.28603  ? 206 LYS H CG  1 
ATOM   1525 C CD  . LYS A 1 210 ? -9.06997  23.93422 9.86937   1.000 38.86650  ? 206 LYS H CD  1 
ATOM   1526 C CE  . LYS A 1 210 ? -10.41912 24.45956 9.37510   1.000 43.59943  ? 206 LYS H CE  1 
ATOM   1527 N NZ  . LYS A 1 210 ? -10.54050 25.95384 9.45240   1.000 45.46066  ? 206 LYS H NZ  1 
ATOM   1528 N N   . VAL A 1 211 ? -11.35320 19.78120 11.12056  1.000 24.85361  ? 207 VAL H N   1 
ATOM   1529 C CA  . VAL A 1 211 ? -12.70681 19.59972 11.63253  1.000 19.87120  ? 207 VAL H CA  1 
ATOM   1530 C C   . VAL A 1 211 ? -12.95354 20.66287 12.69132  1.000 23.92332  ? 207 VAL H C   1 
ATOM   1531 O O   . VAL A 1 211 ? -12.17742 20.77004 13.64242  1.000 26.81853  ? 207 VAL H O   1 
ATOM   1532 C CB  . VAL A 1 211 ? -12.91908 18.19659 12.23829  1.000 22.26181  ? 207 VAL H CB  1 
ATOM   1533 C CG1 . VAL A 1 211 ? -14.36131 18.03836 12.73709  1.000 22.04968  ? 207 VAL H CG1 1 
ATOM   1534 C CG2 . VAL A 1 211 ? -12.55900 17.09609 11.25171  1.000 22.76046  ? 207 VAL H CG2 1 
ATOM   1535 N N   . ASP A 1 212 ? -14.01507 21.45397 12.52773  1.000 20.48582  ? 208 ASP H N   1 
ATOM   1536 C CA  . ASP A 1 212 ? -14.42098 22.43651 13.53164  1.000 25.24297  ? 208 ASP H CA  1 
ATOM   1537 C C   . ASP A 1 212 ? -15.76372 22.00067 14.09503  1.000 28.77812  ? 208 ASP H C   1 
ATOM   1538 O O   . ASP A 1 212 ? -16.73822 21.87237 13.34055  1.000 31.30580  ? 208 ASP H O   1 
ATOM   1539 C CB  . ASP A 1 212 ? -14.51853 23.85039 12.94698  1.000 22.38145  ? 208 ASP H CB  1 
ATOM   1540 C CG  . ASP A 1 212 ? -13.19120 24.34947 12.38991  1.000 34.94345  ? 208 ASP H CG  1 
ATOM   1541 O OD1 . ASP A 1 212 ? -12.24029 24.57870 13.16111  1.000 30.92535  ? 208 ASP H OD1 1 
ATOM   1542 O OD2 . ASP A 1 212 ? -13.08923 24.50657 11.16139  1.000 38.89141  ? 208 ASP H OD2 1 
ATOM   1543 N N   . LYS A 1 213 ? -15.81822 21.77243 15.41291  1.000 19.93917  ? 209 LYS H N   1 
ATOM   1544 C CA  . LYS A 1 213 ? -17.01394 21.21843 16.03424  1.000 23.23242  ? 209 LYS H CA  1 
ATOM   1545 C C   . LYS A 1 213 ? -17.47633 22.09426 17.18982  1.000 29.51716  ? 209 LYS H C   1 
ATOM   1546 O O   . LYS A 1 213 ? -16.71728 22.33567 18.13055  1.000 22.34023  ? 209 LYS H O   1 
ATOM   1547 C CB  . LYS A 1 213 ? -16.77508 19.79467 16.52764  1.000 22.58386  ? 209 LYS H CB  1 
ATOM   1548 C CG  . LYS A 1 213 ? -18.05947 19.16281 17.02630  1.000 29.87683  ? 209 LYS H CG  1 
ATOM   1549 C CD  . LYS A 1 213 ? -17.94873 17.66951 17.02338  1.000 32.89424  ? 209 LYS H CD  1 
ATOM   1550 C CE  . LYS A 1 213 ? -19.23599 17.05487 16.57742  1.000 40.29927  ? 209 LYS H CE  1 
ATOM   1551 N NZ  . LYS A 1 213 ? -19.16868 16.76401 15.13543  1.000 32.19519  ? 209 LYS H NZ  1 
ATOM   1552 N N   . LYS A 1 214 ? -18.72458 22.54489 17.12716  1.000 23.48567  ? 210 LYS H N   1 
ATOM   1553 C CA  . LYS A 1 214 ? -19.32811 23.27288 18.23177  1.000 30.66315  ? 210 LYS H CA  1 
ATOM   1554 C C   . LYS A 1 214 ? -19.80643 22.26635 19.27505  1.000 26.41306  ? 210 LYS H C   1 
ATOM   1555 O O   . LYS A 1 214 ? -20.57272 21.34920 18.96150  1.000 30.77682  ? 210 LYS H O   1 
ATOM   1556 C CB  . LYS A 1 214 ? -20.47821 24.14383 17.72290  1.000 34.67353  ? 210 LYS H CB  1 
ATOM   1557 C CG  . LYS A 1 214 ? -21.14135 25.03990 18.77569  1.000 31.93448  ? 210 LYS H CG  1 
ATOM   1558 C CD  . LYS A 1 214 ? -22.24893 25.88135 18.14869  1.000 35.41904  ? 210 LYS H CD  1 
ATOM   1559 C CE  . LYS A 1 214 ? -22.83160 26.92665 19.11659  1.000 49.36809  ? 210 LYS H CE  1 
ATOM   1560 N NZ  . LYS A 1 214 ? -23.48044 26.36101 20.33231  1.000 48.09429  ? 210 LYS H NZ  1 
ATOM   1561 N N   . VAL A 1 215 ? -19.34201 22.42374 20.50629  1.000 24.64371  ? 211 VAL H N   1 
ATOM   1562 C CA  . VAL A 1 215 ? -19.66697 21.51350 21.59763  1.000 20.59425  ? 211 VAL H CA  1 
ATOM   1563 C C   . VAL A 1 215 ? -20.72842 22.20003 22.45192  1.000 29.61016  ? 211 VAL H C   1 
ATOM   1564 O O   . VAL A 1 215 ? -20.43388 23.18012 23.14281  1.000 23.34616  ? 211 VAL H O   1 
ATOM   1565 C CB  . VAL A 1 215 ? -18.41811 21.16642 22.42679  1.000 19.28832  ? 211 VAL H CB  1 
ATOM   1566 C CG1 . VAL A 1 215 ? -18.78682 20.32639 23.64194  1.000 19.93481  ? 211 VAL H CG1 1 
ATOM   1567 C CG2 . VAL A 1 215 ? -17.37186 20.44591 21.58192  1.000 21.68503  ? 211 VAL H CG2 1 
ATOM   1568 N N   . GLU A 1 216 ? -21.96925 21.68600 22.41337  1.000 29.39479  ? 212 GLU H N   1 
ATOM   1569 C CA  . GLU A 1 216 ? -23.13467 22.26001 23.08473  1.000 34.45894  ? 212 GLU H CA  1 
ATOM   1570 C C   . GLU A 1 216 ? -23.51966 21.44657 24.31781  1.000 34.94020  ? 212 GLU H C   1 
ATOM   1571 O O   . GLU A 1 216 ? -23.29579 20.23212 24.36270  1.000 31.09648  ? 212 GLU H O   1 
ATOM   1572 C CB  . GLU A 1 216 ? -24.34123 22.30994 22.13484  1.000 34.11285  ? 212 GLU H CB  1 
ATOM   1573 C CG  . GLU A 1 216 ? -24.14284 23.19973 20.90912  1.000 47.79678  ? 212 GLU H CG  1 
ATOM   1574 C CD  . GLU A 1 216 ? -25.29036 23.11027 19.90746  1.000 51.40708  ? 212 GLU H CD  1 
ATOM   1575 O OE1 . GLU A 1 216 ? -26.01494 22.08921 19.90900  1.000 53.21424  ? 212 GLU H OE1 1 
ATOM   1576 O OE2 . GLU A 1 216 ? -25.46050 24.06487 19.11728  1.000 58.32639  ? 212 GLU H OE2 1 
ATOM   1577 N N   . PRO A 1 217 ? -24.13812 22.07677 25.31713  1.000 32.93317  ? 213 PRO H N   1 
ATOM   1578 C CA  . PRO A 1 217 ? -24.59557 21.32720 26.49528  1.000 35.25125  ? 213 PRO H CA  1 
ATOM   1579 C C   . PRO A 1 217 ? -25.62407 20.26560 26.13070  1.000 40.10517  ? 213 PRO H C   1 
ATOM   1580 O O   . PRO A 1 217 ? -26.27407 20.32272 25.08355  1.000 38.32695  ? 213 PRO H O   1 
ATOM   1581 C CB  . PRO A 1 217 ? -25.21223 22.40778 27.39058  1.000 39.26533  ? 213 PRO H CB  1 
ATOM   1582 C CG  . PRO A 1 217 ? -24.61084 23.70171 26.89938  1.000 36.21657  ? 213 PRO H CG  1 
ATOM   1583 C CD  . PRO A 1 217 ? -24.38903 23.52336 25.43884  1.000 35.78354  ? 213 PRO H CD  1 
ATOM   1584 N N   . LYS A 1 218 ? -25.77733 19.30369 27.04100  1.000 41.46802  ? 214 LYS H N   1 
ATOM   1585 C CA  . LYS A 1 218 ? -26.59162 18.09793 26.85785  1.000 52.29697  ? 214 LYS H CA  1 
ATOM   1586 C C   . LYS A 1 218 ? -26.02625 17.23124 25.74387  1.000 61.34780  ? 214 LYS H C   1 
ATOM   1587 O O   . LYS A 1 218 ? -25.49433 16.15076 26.00283  1.000 73.79403  ? 214 LYS H O   1 
ATOM   1588 C CB  . LYS A 1 218 ? -28.06173 18.43553 26.56700  1.000 53.02977  ? 214 LYS H CB  1 
ATOM   1589 C CG  . LYS A 1 218 ? -28.81744 19.01400 27.74575  1.000 54.32772  ? 214 LYS H CG  1 
ATOM   1590 C CD  . LYS A 1 218 ? -30.30984 19.09033 27.44148  1.000 60.17497  ? 214 LYS H CD  1 
ATOM   1591 C CE  . LYS A 1 218 ? -30.98984 20.15564 28.28203  1.000 63.83507  ? 214 LYS H CE  1 
ATOM   1592 N NZ  . LYS A 1 218 ? -30.87283 19.89177 29.74307  1.000 65.30189  ? 214 LYS H NZ  1 
ATOM   1593 N N   . ASP B 2 1   ? 30.75115  7.67932  18.54852  1.000 68.97765  ? 1   ASP L N   1 
ATOM   1594 C CA  . ASP B 2 1   ? 32.06242  8.19678  18.92697  1.000 80.10568  ? 1   ASP L CA  1 
ATOM   1595 C C   . ASP B 2 1   ? 32.02668  8.83939  20.32163  1.000 81.73389  ? 1   ASP L C   1 
ATOM   1596 O O   . ASP B 2 1   ? 32.17388  8.15699  21.33983  1.000 73.10182  ? 1   ASP L O   1 
ATOM   1597 C CB  . ASP B 2 1   ? 32.55217  9.20671  17.88004  1.000 84.04705  ? 1   ASP L CB  1 
ATOM   1598 C CG  . ASP B 2 1   ? 34.02063  9.57255  18.04950  1.000 89.45185  ? 1   ASP L CG  1 
ATOM   1599 O OD1 . ASP B 2 1   ? 34.66268  9.09184  19.01078  1.000 89.86599  ? 1   ASP L OD1 1 
ATOM   1600 O OD2 . ASP B 2 1   ? 34.53188  10.34610 17.20913  1.000 81.87497  ? 1   ASP L OD2 1 
ATOM   1601 N N   . ILE B 2 2   ? 31.82419  10.15567 20.35446  1.000 81.69403  ? 2   ILE L N   1 
ATOM   1602 C CA  . ILE B 2 2   ? 31.85449  10.91993 21.59720  1.000 69.23551  ? 2   ILE L CA  1 
ATOM   1603 C C   . ILE B 2 2   ? 30.59171  10.64729 22.40379  1.000 71.93634  ? 2   ILE L C   1 
ATOM   1604 O O   . ILE B 2 2   ? 29.52838  10.34338 21.85306  1.000 79.44283  ? 2   ILE L O   1 
ATOM   1605 C CB  . ILE B 2 2   ? 32.00912  12.42361 21.29277  1.000 71.08835  ? 2   ILE L CB  1 
ATOM   1606 C CG1 . ILE B 2 2   ? 33.18040  12.66814 20.34088  1.000 71.79319  ? 2   ILE L CG1 1 
ATOM   1607 C CG2 . ILE B 2 2   ? 32.20974  13.21705 22.56478  1.000 68.05907  ? 2   ILE L CG2 1 
ATOM   1608 C CD1 . ILE B 2 2   ? 32.76042  12.92217 18.91568  1.000 72.49998  ? 2   ILE L CD1 1 
ATOM   1609 N N   . GLN B 2 3   ? 30.70430  10.75486 23.72586  1.000 69.86382  ? 3   GLN L N   1 
ATOM   1610 C CA  . GLN B 2 3   ? 29.56088  10.64360 24.61829  1.000 67.03065  ? 3   GLN L CA  1 
ATOM   1611 C C   . GLN B 2 3   ? 29.48770  11.86493 25.52440  1.000 67.24344  ? 3   GLN L C   1 
ATOM   1612 O O   . GLN B 2 3   ? 30.47671  12.57423 25.73193  1.000 67.03829  ? 3   GLN L O   1 
ATOM   1613 C CB  . GLN B 2 3   ? 29.62743  9.38179  25.48693  1.000 72.47183  ? 3   GLN L CB  1 
ATOM   1614 C CG  . GLN B 2 3   ? 29.59333  8.06800  24.72926  1.000 71.19063  ? 3   GLN L CG  1 
ATOM   1615 C CD  . GLN B 2 3   ? 29.74912  6.89006  25.66661  1.000 68.08473  ? 3   GLN L CD  1 
ATOM   1616 O OE1 . GLN B 2 3   ? 30.12370  7.06097  26.82560  1.000 74.89795  ? 3   GLN L OE1 1 
ATOM   1617 N NE2 . GLN B 2 3   ? 29.45949  5.68984  25.17662  1.000 69.29925  ? 3   GLN L NE2 1 
ATOM   1618 N N   . MET B 2 4   ? 28.28928  12.09912 26.06045  1.000 61.51849  ? 4   MET L N   1 
ATOM   1619 C CA  . MET B 2 4   ? 28.04610  13.11037 27.08112  1.000 47.77699  ? 4   MET L CA  1 
ATOM   1620 C C   . MET B 2 4   ? 27.01130  12.56444 28.04867  1.000 52.44684  ? 4   MET L C   1 
ATOM   1621 O O   . MET B 2 4   ? 25.94011  12.11752 27.62768  1.000 55.02295  ? 4   MET L O   1 
ATOM   1622 C CB  . MET B 2 4   ? 27.54966  14.43021 26.48298  1.000 57.02071  ? 4   MET L CB  1 
ATOM   1623 C CG  . MET B 2 4   ? 28.44301  15.02337 25.41799  1.000 49.85179  ? 4   MET L CG  1 
ATOM   1624 S SD  . MET B 2 4   ? 28.18377  16.79369 25.23861  1.000 58.18200  ? 4   MET L SD  1 
ATOM   1625 C CE  . MET B 2 4   ? 29.17247  17.43166 26.58854  1.000 51.69442  ? 4   MET L CE  1 
ATOM   1626 N N   . THR B 2 5   ? 27.32554  12.60530 29.33806  1.000 51.39124  ? 5   THR L N   1 
ATOM   1627 C CA  . THR B 2 5   ? 26.47315  12.02808 30.37016  1.000 59.82484  ? 5   THR L CA  1 
ATOM   1628 C C   . THR B 2 5   ? 26.06939  13.11512 31.35519  1.000 55.22499  ? 5   THR L C   1 
ATOM   1629 O O   . THR B 2 5   ? 26.92940  13.76949 31.95406  1.000 52.13408  ? 5   THR L O   1 
ATOM   1630 C CB  . THR B 2 5   ? 27.18476  10.88764 31.09873  1.000 56.55909  ? 5   THR L CB  1 
ATOM   1631 O OG1 . THR B 2 5   ? 27.65545  9.93096  30.14034  1.000 55.30554  ? 5   THR L OG1 1 
ATOM   1632 C CG2 . THR B 2 5   ? 26.23232  10.20852 32.07828  1.000 45.76870  ? 5   THR L CG2 1 
ATOM   1633 N N   . GLN B 2 6   ? 24.76935  13.30260 31.52299  1.000 43.63932  ? 6   GLN L N   1 
ATOM   1634 C CA  . GLN B 2 6   ? 24.25253  14.26841 32.47186  1.000 45.18251  ? 6   GLN L CA  1 
ATOM   1635 C C   . GLN B 2 6   ? 23.85592  13.54596 33.74890  1.000 43.25999  ? 6   GLN L C   1 
ATOM   1636 O O   . GLN B 2 6   ? 23.52657  12.35861 33.73287  1.000 51.87158  ? 6   GLN L O   1 
ATOM   1637 C CB  . GLN B 2 6   ? 23.05418  15.02535 31.88892  1.000 32.58111  ? 6   GLN L CB  1 
ATOM   1638 C CG  . GLN B 2 6   ? 23.30574  15.56393 30.49060  1.000 34.22266  ? 6   GLN L CG  1 
ATOM   1639 C CD  . GLN B 2 6   ? 22.13408  16.35222 29.92566  1.000 32.18546  ? 6   GLN L CD  1 
ATOM   1640 O OE1 . GLN B 2 6   ? 22.00959  16.51144 28.70806  1.000 32.27658  ? 6   GLN L OE1 1 
ATOM   1641 N NE2 . GLN B 2 6   ? 21.27720  16.85695 30.80445  1.000 30.80885  ? 6   GLN L NE2 1 
ATOM   1642 N N   . SER B 2 7   ? 23.91342  14.26558 34.86486  1.000 39.13885  ? 7   SER L N   1 
ATOM   1643 C CA  . SER B 2 7   ? 23.46458  13.70618 36.12299  1.000 51.72509  ? 7   SER L CA  1 
ATOM   1644 C C   . SER B 2 7   ? 22.76094  14.81110 36.89619  1.000 38.14496  ? 7   SER L C   1 
ATOM   1645 O O   . SER B 2 7   ? 23.20724  15.96758 36.87354  1.000 47.47765  ? 7   SER L O   1 
ATOM   1646 C CB  . SER B 2 7   ? 24.61518  13.11441 36.95854  1.000 48.74100  ? 7   SER L CB  1 
ATOM   1647 O OG  . SER B 2 7   ? 25.64441  14.06369 37.16947  1.000 48.13294  ? 7   SER L OG  1 
ATOM   1648 N N   . PRO B 2 8   ? 21.63398  14.50047 37.54497  1.000 40.22809  ? 8   PRO L N   1 
ATOM   1649 C CA  . PRO B 2 8   ? 21.01051  13.17711 37.48378  1.000 43.32374  ? 8   PRO L CA  1 
ATOM   1650 C C   . PRO B 2 8   ? 20.20710  13.03243 36.20093  1.000 45.58311  ? 8   PRO L C   1 
ATOM   1651 O O   . PRO B 2 8   ? 20.24748  13.94772 35.37993  1.000 52.69504  ? 8   PRO L O   1 
ATOM   1652 C CB  . PRO B 2 8   ? 20.10918  13.16345 38.71704  1.000 48.46628  ? 8   PRO L CB  1 
ATOM   1653 C CG  . PRO B 2 8   ? 19.69885  14.60379 38.87403  1.000 44.17645  ? 8   PRO L CG  1 
ATOM   1654 C CD  . PRO B 2 8   ? 20.85054  15.44522 38.35991  1.000 40.17873  ? 8   PRO L CD  1 
ATOM   1655 N N   . SER B 2 9   ? 19.51198  11.91015 36.01084  1.000 47.03941  ? 9   SER L N   1 
ATOM   1656 C CA  . SER B 2 9   ? 18.66106  11.77359 34.83384  1.000 45.41733  ? 9   SER L CA  1 
ATOM   1657 C C   . SER B 2 9   ? 17.30380  12.42759 35.03593  1.000 41.71402  ? 9   SER L C   1 
ATOM   1658 O O   . SER B 2 9   ? 16.63666  12.76460 34.05270  1.000 37.60251  ? 9   SER L O   1 
ATOM   1659 C CB  . SER B 2 9   ? 18.47901  10.29834 34.47263  1.000 46.88336  ? 9   SER L CB  1 
ATOM   1660 O OG  . SER B 2 9   ? 19.68043  9.75248  33.95424  1.000 54.11919  ? 9   SER L OG  1 
ATOM   1661 N N   . SER B 2 10  ? 16.89303  12.61687 36.28743  1.000 42.52827  ? 10  SER L N   1 
ATOM   1662 C CA  . SER B 2 10  ? 15.64378  13.28475 36.61635  1.000 39.64611  ? 10  SER L CA  1 
ATOM   1663 C C   . SER B 2 10  ? 15.74567  13.80378 38.04039  1.000 41.94424  ? 10  SER L C   1 
ATOM   1664 O O   . SER B 2 10  ? 16.52555  13.29637 38.84965  1.000 44.34226  ? 10  SER L O   1 
ATOM   1665 C CB  . SER B 2 10  ? 14.43930  12.34756 36.46483  1.000 44.48985  ? 10  SER L CB  1 
ATOM   1666 O OG  . SER B 2 10  ? 14.66913  11.10203 37.10282  1.000 49.28815  ? 10  SER L OG  1 
ATOM   1667 N N   . LEU B 2 11  ? 14.94668  14.82290 38.33839  1.000 34.14061  ? 11  LEU L N   1 
ATOM   1668 C CA  . LEU B 2 11  ? 14.94904  15.37028 39.68186  1.000 39.71064  ? 11  LEU L CA  1 
ATOM   1669 C C   . LEU B 2 11  ? 13.64137  16.09816 39.92172  1.000 42.66209  ? 11  LEU L C   1 
ATOM   1670 O O   . LEU B 2 11  ? 12.98765  16.57161 38.98713  1.000 34.69379  ? 11  LEU L O   1 
ATOM   1671 C CB  . LEU B 2 11  ? 16.13235  16.31553 39.91488  1.000 38.30146  ? 11  LEU L CB  1 
ATOM   1672 C CG  . LEU B 2 11  ? 16.16676  17.60661 39.09692  1.000 42.48697  ? 11  LEU L CG  1 
ATOM   1673 C CD1 . LEU B 2 11  ? 15.54938  18.77681 39.85690  1.000 32.95489  ? 11  LEU L CD1 1 
ATOM   1674 C CD2 . LEU B 2 11  ? 17.59448  17.92105 38.67154  1.000 31.94598  ? 11  LEU L CD2 1 
ATOM   1675 N N   . SER B 2 12  ? 13.27911  16.17386 41.19327  1.000 34.83773  ? 12  SER L N   1 
ATOM   1676 C CA  . SER B 2 12  ? 12.13159  16.92682 41.66130  1.000 31.08359  ? 12  SER L CA  1 
ATOM   1677 C C   . SER B 2 12  ? 12.63061  17.94907 42.67365  1.000 40.80849  ? 12  SER L C   1 
ATOM   1678 O O   . SER B 2 12  ? 13.45192  17.62126 43.53448  1.000 40.77529  ? 12  SER L O   1 
ATOM   1679 C CB  . SER B 2 12  ? 11.09219  15.98786 42.28715  1.000 38.57087  ? 12  SER L CB  1 
ATOM   1680 O OG  . SER B 2 12  ? 9.99987   16.71273 42.82210  1.000 48.31431  ? 12  SER L OG  1 
ATOM   1681 N N   . ALA B 2 13  ? 12.15324  19.18531 42.56124  1.000 33.77497  ? 13  ALA L N   1 
ATOM   1682 C CA  . ALA B 2 13  ? 12.60596  20.25039 43.44134  1.000 35.08758  ? 13  ALA L CA  1 
ATOM   1683 C C   . ALA B 2 13  ? 11.48131  21.25574 43.58555  1.000 36.76142  ? 13  ALA L C   1 
ATOM   1684 O O   . ALA B 2 13  ? 10.56731  21.31304 42.75880  1.000 41.06037  ? 13  ALA L O   1 
ATOM   1685 C CB  . ALA B 2 13  ? 13.87563  20.92761 42.91140  1.000 35.73927  ? 13  ALA L CB  1 
ATOM   1686 N N   . SER B 2 14  ? 11.55455  22.04290 44.65042  1.000 31.73015  ? 14  SER L N   1 
ATOM   1687 C CA  . SER B 2 14  ? 10.50926  22.99255 44.99335  1.000 29.17663  ? 14  SER L CA  1 
ATOM   1688 C C   . SER B 2 14  ? 10.74404  24.32876 44.30865  1.000 30.39805  ? 14  SER L C   1 
ATOM   1689 O O   . SER B 2 14  ? 11.87564  24.70073 43.99271  1.000 31.51828  ? 14  SER L O   1 
ATOM   1690 C CB  . SER B 2 14  ? 10.44499  23.20544 46.51058  1.000 30.70912  ? 14  SER L CB  1 
ATOM   1691 O OG  . SER B 2 14  ? 9.87120   22.08423 47.15025  1.000 37.03254  ? 14  SER L OG  1 
ATOM   1692 N N   . VAL B 2 15  ? 9.64499   25.05482 44.09261  1.000 25.25898  ? 15  VAL L N   1 
ATOM   1693 C CA  . VAL B 2 15  ? 9.73038   26.41896 43.59898  1.000 33.79662  ? 15  VAL L CA  1 
ATOM   1694 C C   . VAL B 2 15  ? 10.61439  27.22685 44.53548  1.000 41.38476  ? 15  VAL L C   1 
ATOM   1695 O O   . VAL B 2 15  ? 10.42099  27.21740 45.75828  1.000 36.05949  ? 15  VAL L O   1 
ATOM   1696 C CB  . VAL B 2 15  ? 8.32837   27.03309 43.48426  1.000 29.68011  ? 15  VAL L CB  1 
ATOM   1697 C CG1 . VAL B 2 15  ? 8.42931   28.52375 43.27765  1.000 34.42179  ? 15  VAL L CG1 1 
ATOM   1698 C CG2 . VAL B 2 15  ? 7.53828   26.39146 42.33564  1.000 33.21480  ? 15  VAL L CG2 1 
ATOM   1699 N N   . GLY B 2 16  ? 11.59944  27.92281 43.96477  1.000 36.24045  ? 16  GLY L N   1 
ATOM   1700 C CA  . GLY B 2 16  ? 12.54324  28.70707 44.72666  1.000 31.90785  ? 16  GLY L CA  1 
ATOM   1701 C C   . GLY B 2 16  ? 13.83696  27.99096 45.03778  1.000 33.07747  ? 16  GLY L C   1 
ATOM   1702 O O   . GLY B 2 16  ? 14.79933  28.64172 45.46435  1.000 43.57990  ? 16  GLY L O   1 
ATOM   1703 N N   . ASP B 2 17  ? 13.88802  26.67695 44.83733  1.000 32.74585  ? 17  ASP L N   1 
ATOM   1704 C CA  . ASP B 2 17  ? 15.11668  25.92894 45.03464  1.000 36.52342  ? 17  ASP L CA  1 
ATOM   1705 C C   . ASP B 2 17  ? 16.16644  26.32506 44.00144  1.000 44.54364  ? 17  ASP L C   1 
ATOM   1706 O O   . ASP B 2 17  ? 15.86073  26.81181 42.91038  1.000 42.95222  ? 17  ASP L O   1 
ATOM   1707 C CB  . ASP B 2 17  ? 14.86552  24.42201 44.94100  1.000 39.70564  ? 17  ASP L CB  1 
ATOM   1708 C CG  . ASP B 2 17  ? 14.13239  23.86819 46.15490  1.000 36.79060  ? 17  ASP L CG  1 
ATOM   1709 O OD1 . ASP B 2 17  ? 13.66603  24.67436 46.99386  1.000 42.44816  ? 17  ASP L OD1 1 
ATOM   1710 O OD2 . ASP B 2 17  ? 14.02684  22.62256 46.25989  1.000 38.85102  ? 17  ASP L OD2 1 
ATOM   1711 N N   . ARG B 2 18  ? 17.42356  26.11563 44.36833  1.000 39.53478  ? 18  ARG L N   1 
ATOM   1712 C CA  . ARG B 2 18  ? 18.52490  26.20487 43.42581  1.000 45.87644  ? 18  ARG L CA  1 
ATOM   1713 C C   . ARG B 2 18  ? 18.75776  24.80697 42.87557  1.000 48.02004  ? 18  ARG L C   1 
ATOM   1714 O O   . ARG B 2 18  ? 18.81328  23.84032 43.64314  1.000 41.72880  ? 18  ARG L O   1 
ATOM   1715 C CB  . ARG B 2 18  ? 19.78501  26.74986 44.10390  1.000 52.92338  ? 18  ARG L CB  1 
ATOM   1716 C CG  . ARG B 2 18  ? 20.76135  27.47100 43.18087  1.000 54.61559  ? 18  ARG L CG  1 
ATOM   1717 C CD  . ARG B 2 18  ? 21.75420  28.30494 43.99465  1.000 64.87971  ? 18  ARG L CD  1 
ATOM   1718 N NE  . ARG B 2 18  ? 22.74906  28.98309 43.17099  1.000 80.99154  ? 18  ARG L NE  1 
ATOM   1719 C CZ  . ARG B 2 18  ? 22.85417  30.30114 43.05529  1.000 82.86144  ? 18  ARG L CZ  1 
ATOM   1720 N NH1 . ARG B 2 18  ? 22.06038  31.12112 43.72876  1.000 79.28162  ? 18  ARG L NH1 1 
ATOM   1721 N NH2 . ARG B 2 18  ? 23.78092  30.80957 42.24634  1.000 81.23355  ? 18  ARG L NH2 1 
ATOM   1722 N N   . VAL B 2 19  ? 18.85045  24.69871 41.54909  1.000 39.33039  ? 19  VAL L N   1 
ATOM   1723 C CA  . VAL B 2 19  ? 18.96277  23.41875 40.86069  1.000 38.67308  ? 19  VAL L CA  1 
ATOM   1724 C C   . VAL B 2 19  ? 20.26987  23.40886 40.08736  1.000 31.97473  ? 19  VAL L C   1 
ATOM   1725 O O   . VAL B 2 19  ? 20.64718  24.41485 39.47728  1.000 41.80124  ? 19  VAL L O   1 
ATOM   1726 C CB  . VAL B 2 19  ? 17.75868  23.17367 39.92113  1.000 39.54777  ? 19  VAL L CB  1 
ATOM   1727 C CG1 . VAL B 2 19  ? 18.07010  22.09564 38.88626  1.000 36.70286  ? 19  VAL L CG1 1 
ATOM   1728 C CG2 . VAL B 2 19  ? 16.53159  22.79858 40.72649  1.000 34.45197  ? 19  VAL L CG2 1 
ATOM   1729 N N   . THR B 2 20  ? 20.96616  22.27828 40.13100  1.000 30.50376  ? 20  THR L N   1 
ATOM   1730 C CA  . THR B 2 20  ? 22.24472  22.11529 39.45183  1.000 44.49031  ? 20  THR L CA  1 
ATOM   1731 C C   . THR B 2 20  ? 22.22863  20.82379 38.65085  1.000 36.80962  ? 20  THR L C   1 
ATOM   1732 O O   . THR B 2 20  ? 21.88483  19.76046 39.17914  1.000 43.33890  ? 20  THR L O   1 
ATOM   1733 C CB  . THR B 2 20  ? 23.41387  22.10227 40.44640  1.000 37.04252  ? 20  THR L CB  1 
ATOM   1734 O OG1 . THR B 2 20  ? 23.52079  23.38969 41.06329  1.000 41.38167  ? 20  THR L OG1 1 
ATOM   1735 C CG2 . THR B 2 20  ? 24.71426  21.77607 39.73243  1.000 43.02792  ? 20  THR L CG2 1 
ATOM   1736 N N   . ILE B 2 21  ? 22.60265  20.92128 37.38325  1.000 30.37513  ? 21  ILE L N   1 
ATOM   1737 C CA  . ILE B 2 21  ? 22.65950  19.78456 36.47773  1.000 37.39933  ? 21  ILE L CA  1 
ATOM   1738 C C   . ILE B 2 21  ? 24.07759  19.69863 35.93746  1.000 43.27359  ? 21  ILE L C   1 
ATOM   1739 O O   . ILE B 2 21  ? 24.60679  20.68327 35.40645  1.000 44.84459  ? 21  ILE L O   1 
ATOM   1740 C CB  . ILE B 2 21  ? 21.64427  19.91997 35.32851  1.000 39.84478  ? 21  ILE L CB  1 
ATOM   1741 C CG1 . ILE B 2 21  ? 20.23688  20.13146 35.88500  1.000 32.29958  ? 21  ILE L CG1 1 
ATOM   1742 C CG2 . ILE B 2 21  ? 21.70799  18.69689 34.41591  1.000 32.97039  ? 21  ILE L CG2 1 
ATOM   1743 C CD1 . ILE B 2 21  ? 19.19656  20.37788 34.81615  1.000 36.02785  ? 21  ILE L CD1 1 
ATOM   1744 N N   . THR B 2 22  ? 24.68723  18.52857 36.07015  1.000 40.30705  ? 22  THR L N   1 
ATOM   1745 C CA  . THR B 2 22  ? 26.07356  18.32905 35.68035  1.000 51.40814  ? 22  THR L CA  1 
ATOM   1746 C C   . THR B 2 22  ? 26.13023  17.61252 34.33783  1.000 49.41165  ? 22  THR L C   1 
ATOM   1747 O O   . THR B 2 22  ? 25.40559  16.64029 34.10773  1.000 55.11357  ? 22  THR L O   1 
ATOM   1748 C CB  . THR B 2 22  ? 26.82982  17.52004 36.74161  1.000 55.46236  ? 22  THR L CB  1 
ATOM   1749 O OG1 . THR B 2 22  ? 26.83905  16.13806 36.36991  1.000 57.89886  ? 22  THR L OG1 1 
ATOM   1750 C CG2 . THR B 2 22  ? 26.15236  17.64764 38.10948  1.000 44.48479  ? 22  THR L CG2 1 
ATOM   1751 N N   . CYS B 2 23  ? 26.97854  18.10934 33.44923  1.000 49.08217  ? 23  CYS L N   1 
ATOM   1752 C CA  . CYS B 2 23  ? 27.24451  17.47239 32.16976  1.000 53.05156  ? 23  CYS L CA  1 
ATOM   1753 C C   . CYS B 2 23  ? 28.71343  17.07408 32.12364  1.000 61.76221  ? 23  CYS L C   1 
ATOM   1754 O O   . CYS B 2 23  ? 29.56618  17.71232 32.75084  1.000 56.18286  ? 23  CYS L O   1 
ATOM   1755 C CB  . CYS B 2 23  ? 26.89796  18.40820 31.00353  1.000 53.91500  ? 23  CYS L CB  1 
ATOM   1756 S SG  . CYS B 2 23  ? 27.13207  17.77004 29.32824  1.000 73.61891  ? 23  CYS L SG  1 
ATOM   1757 N N   . ARG B 2 24  ? 29.00853  16.01836 31.37094  1.000 63.16818  ? 24  ARG L N   1 
ATOM   1758 C CA  . ARG B 2 24  ? 30.31184  15.37307 31.46722  1.000 57.32234  ? 24  ARG L CA  1 
ATOM   1759 C C   . ARG B 2 24  ? 30.65358  14.72885 30.13559  1.000 47.34782  ? 24  ARG L C   1 
ATOM   1760 O O   . ARG B 2 24  ? 29.99115  13.77291 29.72550  1.000 59.08789  ? 24  ARG L O   1 
ATOM   1761 C CB  . ARG B 2 24  ? 30.28847  14.33968 32.58262  1.000 64.22230  ? 24  ARG L CB  1 
ATOM   1762 C CG  . ARG B 2 24  ? 31.58572  13.65199 32.82763  1.000 72.21073  ? 24  ARG L CG  1 
ATOM   1763 C CD  . ARG B 2 24  ? 31.43605  12.76410 34.04301  1.000 79.04597  ? 24  ARG L CD  1 
ATOM   1764 N NE  . ARG B 2 24  ? 30.79844  11.48475 33.75260  1.000 81.65297  ? 24  ARG L NE  1 
ATOM   1765 C CZ  . ARG B 2 24  ? 31.36778  10.49163 33.07998  1.000 78.92309  ? 24  ARG L CZ  1 
ATOM   1766 N NH1 . ARG B 2 24  ? 32.55785  10.62667 32.51524  1.000 75.58654  ? 24  ARG L NH1 1 
ATOM   1767 N NH2 . ARG B 2 24  ? 30.72718  9.33179  32.97145  1.000 72.05833  ? 24  ARG L NH2 1 
ATOM   1768 N N   . ALA B 2 25  ? 31.68422  15.24108 29.47342  1.000 51.42166  ? 25  ALA L N   1 
ATOM   1769 C CA  . ALA B 2 25  ? 32.02740  14.83400 28.11933  1.000 52.68084  ? 25  ALA L CA  1 
ATOM   1770 C C   . ALA B 2 25  ? 33.09000  13.74124 28.11814  1.000 64.48802  ? 25  ALA L C   1 
ATOM   1771 O O   . ALA B 2 25  ? 33.90768  13.64344 29.03498  1.000 66.05607  ? 25  ALA L O   1 
ATOM   1772 C CB  . ALA B 2 25  ? 32.52486  16.02948 27.30763  1.000 56.43939  ? 25  ALA L CB  1 
ATOM   1773 N N   . SER B 2 26  ? 33.07497  12.92270 27.06224  1.000 68.52762  ? 26  SER L N   1 
ATOM   1774 C CA  . SER B 2 26  ? 34.06694  11.86931 26.88546  1.000 64.93725  ? 26  SER L CA  1 
ATOM   1775 C C   . SER B 2 26  ? 35.39339  12.39403 26.35290  1.000 65.38923  ? 26  SER L C   1 
ATOM   1776 O O   . SER B 2 26  ? 36.38385  11.65588 26.37184  1.000 67.92094  ? 26  SER L O   1 
ATOM   1777 C CB  . SER B 2 26  ? 33.53052  10.78398 25.94367  1.000 61.26522  ? 26  SER L CB  1 
ATOM   1778 O OG  . SER B 2 26  ? 33.54029  11.21979 24.59564  1.000 64.02433  ? 26  SER L OG  1 
ATOM   1779 N N   . GLN B 2 27  ? 35.43082  13.63590 25.87144  1.000 63.46505  ? 27  GLN L N   1 
ATOM   1780 C CA  . GLN B 2 27  ? 36.65094  14.28023 25.41055  1.000 60.44486  ? 27  GLN L CA  1 
ATOM   1781 C C   . GLN B 2 27  ? 36.59457  15.75226 25.78527  1.000 63.91341  ? 27  GLN L C   1 
ATOM   1782 O O   . GLN B 2 27  ? 35.58017  16.25424 26.27789  1.000 62.89829  ? 27  GLN L O   1 
ATOM   1783 C CB  . GLN B 2 27  ? 36.83836  14.15715 23.89343  1.000 59.72135  ? 27  GLN L CB  1 
ATOM   1784 C CG  . GLN B 2 27  ? 36.76889  12.75341 23.34150  1.000 66.88696  ? 27  GLN L CG  1 
ATOM   1785 C CD  . GLN B 2 27  ? 36.60949  12.75018 21.83566  1.000 71.18465  ? 27  GLN L CD  1 
ATOM   1786 O OE1 . GLN B 2 27  ? 36.78241  13.78224 21.18122  1.000 72.95077  ? 27  GLN L OE1 1 
ATOM   1787 N NE2 . GLN B 2 27  ? 36.26944  11.59302 21.27614  1.000 65.67457  ? 27  GLN L NE2 1 
ATOM   1788 N N   . SER B 2 28  A 37.69659  16.45060 25.53230  1.000 61.36262  ? 27  SER L N   1 
ATOM   1789 C CA  . SER B 2 28  A 37.69668  17.89980 25.65911  1.000 61.23240  ? 27  SER L CA  1 
ATOM   1790 C C   . SER B 2 28  A 36.91034  18.51291 24.51025  1.000 58.08734  ? 27  SER L C   1 
ATOM   1791 O O   . SER B 2 28  A 37.08901  18.13801 23.34642  1.000 55.52794  ? 27  SER L O   1 
ATOM   1792 C CB  . SER B 2 28  A 39.12490  18.44357 25.67700  1.000 61.99787  ? 27  SER L CB  1 
ATOM   1793 O OG  . SER B 2 28  A 39.70414  18.32288 26.96710  1.000 64.37919  ? 27  SER L OG  1 
ATOM   1794 N N   . VAL B 2 29  B 36.03205  19.45205 24.84084  1.000 59.06372  ? 27  VAL L N   1 
ATOM   1795 C CA  . VAL B 2 29  B 35.23646  20.11345 23.81870  1.000 56.04725  ? 27  VAL L CA  1 
ATOM   1796 C C   . VAL B 2 29  B 36.09783  21.12436 23.06988  1.000 55.31453  ? 27  VAL L C   1 
ATOM   1797 O O   . VAL B 2 29  B 37.14944  21.56228 23.54511  1.000 58.58138  ? 27  VAL L O   1 
ATOM   1798 C CB  . VAL B 2 29  B 33.99095  20.77672 24.43466  1.000 55.88807  ? 27  VAL L CB  1 
ATOM   1799 C CG1 . VAL B 2 29  B 33.12700  19.72824 25.12613  1.000 44.69101  ? 27  VAL L CG1 1 
ATOM   1800 C CG2 . VAL B 2 29  B 34.39044  21.86699 25.41960  1.000 46.97976  ? 27  VAL L CG2 1 
ATOM   1801 N N   . TRP B 2 30  ? 35.63526  21.48920 21.87792  1.000 50.63670  ? 28  TRP L N   1 
ATOM   1802 C CA  . TRP B 2 30  ? 36.34333  22.41483 21.00131  1.000 51.02635  ? 28  TRP L CA  1 
ATOM   1803 C C   . TRP B 2 30  ? 36.72596  23.69100 21.73511  1.000 57.92083  ? 28  TRP L C   1 
ATOM   1804 O O   . TRP B 2 30  ? 35.86501  24.39031 22.27683  1.000 58.45673  ? 28  TRP L O   1 
ATOM   1805 C CB  . TRP B 2 30  ? 35.46065  22.73580 19.79422  1.000 38.70134  ? 28  TRP L CB  1 
ATOM   1806 C CG  . TRP B 2 30  ? 36.06492  23.65577 18.78606  1.000 52.51207  ? 28  TRP L CG  1 
ATOM   1807 C CD1 . TRP B 2 30  ? 35.60792  24.89460 18.42839  1.000 53.43566  ? 28  TRP L CD1 1 
ATOM   1808 C CD2 . TRP B 2 30  ? 37.22291  23.40651 17.97698  1.000 58.43579  ? 28  TRP L CD2 1 
ATOM   1809 N NE1 . TRP B 2 30  ? 36.41284  25.43240 17.45315  1.000 60.69098  ? 28  TRP L NE1 1 
ATOM   1810 C CE2 . TRP B 2 30  ? 37.41067  24.54018 17.15637  1.000 60.58837  ? 28  TRP L CE2 1 
ATOM   1811 C CE3 . TRP B 2 30  ? 38.12074  22.33710 17.86818  1.000 60.24237  ? 28  TRP L CE3 1 
ATOM   1812 C CZ2 . TRP B 2 30  ? 38.46316  24.63672 16.24271  1.000 65.34172  ? 28  TRP L CZ2 1 
ATOM   1813 C CZ3 . TRP B 2 30  ? 39.16697  22.43347 16.95801  1.000 60.29978  ? 28  TRP L CZ3 1 
ATOM   1814 C CH2 . TRP B 2 30  ? 39.32743  23.57619 16.15791  1.000 62.17653  ? 28  TRP L CH2 1 
ATOM   1815 N N   . ARG B 2 31  ? 38.02916  23.97718 21.76176  1.000 61.00056  ? 29  ARG L N   1 
ATOM   1816 C CA  . ARG B 2 31  ? 38.59921  25.17048 22.38669  1.000 53.22518  ? 29  ARG L CA  1 
ATOM   1817 C C   . ARG B 2 31  ? 38.26746  25.27341 23.87830  1.000 59.14211  ? 29  ARG L C   1 
ATOM   1818 O O   . ARG B 2 31  ? 38.43524  26.34013 24.47907  1.000 52.69812  ? 29  ARG L O   1 
ATOM   1819 C CB  . ARG B 2 31  ? 38.15392  26.44618 21.65675  1.000 55.38402  ? 29  ARG L CB  1 
ATOM   1820 C CG  . ARG B 2 31  ? 38.27162  26.37911 20.14138  1.000 56.53010  ? 29  ARG L CG  1 
ATOM   1821 C CD  . ARG B 2 31  ? 38.85573  27.66233 19.56269  1.000 68.43241  ? 29  ARG L CD  1 
ATOM   1822 N NE  . ARG B 2 31  ? 37.96431  28.81099 19.69020  1.000 79.64944  ? 29  ARG L NE  1 
ATOM   1823 C CZ  . ARG B 2 31  ? 38.29926  30.05700 19.37336  1.000 81.77566  ? 29  ARG L CZ  1 
ATOM   1824 N NH1 . ARG B 2 31  ? 39.50749  30.35549 18.91871  1.000 77.26212  ? 29  ARG L NH1 1 
ATOM   1825 N NH2 . ARG B 2 31  ? 37.39983  31.02835 19.51497  1.000 79.43317  ? 29  ARG L NH2 1 
ATOM   1826 N N   . ASN B 2 32  ? 37.82591  24.17413 24.49622  1.000 61.45792  ? 30  ASN L N   1 
ATOM   1827 C CA  . ASN B 2 32  ? 37.26219  24.19303 25.85251  1.000 63.44401  ? 30  ASN L CA  1 
ATOM   1828 C C   . ASN B 2 32  ? 36.26667  25.34076 26.02175  1.000 54.46241  ? 30  ASN L C   1 
ATOM   1829 O O   . ASN B 2 32  ? 36.19137  25.97707 27.07469  1.000 61.92889  ? 30  ASN L O   1 
ATOM   1830 C CB  . ASN B 2 32  ? 38.36400  24.26470 26.91002  1.000 58.17814  ? 30  ASN L CB  1 
ATOM   1831 C CG  . ASN B 2 32  ? 39.24654  23.03612 26.91013  1.000 61.70280  ? 30  ASN L CG  1 
ATOM   1832 O OD1 . ASN B 2 32  ? 38.82614  21.96153 26.48551  1.000 71.08948  ? 30  ASN L OD1 1 
ATOM   1833 N ND2 . ASN B 2 32  ? 40.47747  23.18647 27.38458  1.000 60.20995  ? 30  ASN L ND2 1 
ATOM   1834 N N   . LYS B 2 33  ? 35.49680  25.60273 24.96958  1.000 50.48195  ? 31  LYS L N   1 
ATOM   1835 C CA  . LYS B 2 33  ? 34.56147  26.71883 24.87925  1.000 56.40464  ? 31  LYS L CA  1 
ATOM   1836 C C   . LYS B 2 33  ? 33.16178  26.30645 24.43111  1.000 61.80223  ? 31  LYS L C   1 
ATOM   1837 O O   . LYS B 2 33  ? 32.17868  26.83322 24.95730  1.000 53.07540  ? 31  LYS L O   1 
ATOM   1838 C CB  . LYS B 2 33  ? 35.12339  27.78455 23.91376  1.000 52.32003  ? 31  LYS L CB  1 
ATOM   1839 C CG  . LYS B 2 33  ? 34.41601  29.13575 23.97323  1.000 59.18794  ? 31  LYS L CG  1 
ATOM   1840 C CD  . LYS B 2 33  ? 34.82693  30.05270 22.81749  1.000 57.60576  ? 31  LYS L CD  1 
ATOM   1841 C CE  . LYS B 2 33  ? 34.60370  29.36829 21.46737  1.000 65.10790  ? 31  LYS L CE  1 
ATOM   1842 N NZ  . LYS B 2 33  ? 34.60835  30.30882 20.30357  1.000 62.81026  ? 31  LYS L NZ  1 
ATOM   1843 N N   . ASN B 2 34  ? 33.04067  25.37049 23.48315  1.000 53.42680  ? 32  ASN L N   1 
ATOM   1844 C CA  . ASN B 2 34  ? 31.76479  25.12065 22.80444  1.000 46.36692  ? 32  ASN L CA  1 
ATOM   1845 C C   . ASN B 2 34  ? 30.92629  24.09078 23.56143  1.000 44.96155  ? 32  ASN L C   1 
ATOM   1846 O O   . ASN B 2 34  ? 30.85051  22.91468 23.20491  1.000 45.66305  ? 32  ASN L O   1 
ATOM   1847 C CB  . ASN B 2 34  ? 32.00887  24.68156 21.36844  1.000 47.47353  ? 32  ASN L CB  1 
ATOM   1848 C CG  . ASN B 2 34  ? 32.59990  25.78193 20.51903  1.000 52.29202  ? 32  ASN L CG  1 
ATOM   1849 O OD1 . ASN B 2 34  ? 33.54896  26.44709 20.92538  1.000 52.81341  ? 32  ASN L OD1 1 
ATOM   1850 N ND2 . ASN B 2 34  ? 32.03110  25.99137 19.33842  1.000 38.31988  ? 32  ASN L ND2 1 
ATOM   1851 N N   . VAL B 2 35  ? 30.26771  24.55830 24.62110  1.000 45.17209  ? 33  VAL L N   1 
ATOM   1852 C CA  . VAL B 2 35  ? 29.19106  23.82551 25.28264  1.000 38.27614  ? 33  VAL L CA  1 
ATOM   1853 C C   . VAL B 2 35  ? 27.98995  24.75595 25.40204  1.000 41.02920  ? 33  VAL L C   1 
ATOM   1854 O O   . VAL B 2 35  ? 28.12953  25.90493 25.83636  1.000 37.19711  ? 33  VAL L O   1 
ATOM   1855 C CB  . VAL B 2 35  ? 29.60631  23.29451 26.66598  1.000 40.26999  ? 33  VAL L CB  1 
ATOM   1856 C CG1 . VAL B 2 35  ? 28.39117  22.86267 27.44951  1.000 45.33971  ? 33  VAL L CG1 1 
ATOM   1857 C CG2 . VAL B 2 35  ? 30.53084  22.12521 26.49982  1.000 46.51286  ? 33  VAL L CG2 1 
ATOM   1858 N N   . ALA B 2 36  ? 26.81972  24.27729 24.98528  1.000 34.79101  ? 34  ALA L N   1 
ATOM   1859 C CA  . ALA B 2 36  ? 25.57949  25.01281 25.16744  1.000 29.45833  ? 34  ALA L CA  1 
ATOM   1860 C C   . ALA B 2 36  ? 24.60695  24.18336 26.00347  1.000 35.87683  ? 34  ALA L C   1 
ATOM   1861 O O   . ALA B 2 36  ? 24.77033  22.97082 26.16130  1.000 34.45798  ? 34  ALA L O   1 
ATOM   1862 C CB  . ALA B 2 36  ? 24.95517  25.38631 23.81955  1.000 29.78713  ? 34  ALA L CB  1 
ATOM   1863 N N   . TRP B 2 37  ? 23.60591  24.85524 26.57401  1.000 32.70837  ? 35  TRP L N   1 
ATOM   1864 C CA  . TRP B 2 37  ? 22.51234  24.19346 27.27801  1.000 29.40415  ? 35  TRP L CA  1 
ATOM   1865 C C   . TRP B 2 37  ? 21.19874  24.53935 26.59300  1.000 31.74399  ? 35  TRP L C   1 
ATOM   1866 O O   . TRP B 2 37  ? 20.94627  25.71111 26.27514  1.000 29.32192  ? 35  TRP L O   1 
ATOM   1867 C CB  . TRP B 2 37  ? 22.46185  24.59302 28.75913  1.000 31.49662  ? 35  TRP L CB  1 
ATOM   1868 C CG  . TRP B 2 37  ? 23.60240  24.05264 29.53944  1.000 38.57376  ? 35  TRP L CG  1 
ATOM   1869 C CD1 . TRP B 2 37  ? 24.81077  24.65557 29.75459  1.000 42.23405  ? 35  TRP L CD1 1 
ATOM   1870 C CD2 . TRP B 2 37  ? 23.66283  22.78378 30.20660  1.000 35.04528  ? 35  TRP L CD2 1 
ATOM   1871 N NE1 . TRP B 2 37  ? 25.61636  23.84189 30.52170  1.000 37.51174  ? 35  TRP L NE1 1 
ATOM   1872 C CE2 . TRP B 2 37  ? 24.93748  22.68614 30.80600  1.000 36.79338  ? 35  TRP L CE2 1 
ATOM   1873 C CE3 . TRP B 2 37  ? 22.76331  21.72221 30.35540  1.000 30.97784  ? 35  TRP L CE3 1 
ATOM   1874 C CZ2 . TRP B 2 37  ? 25.33105  21.57400 31.54363  1.000 38.94118  ? 35  TRP L CZ2 1 
ATOM   1875 C CZ3 . TRP B 2 37  ? 23.15680  20.61660 31.08227  1.000 32.86077  ? 35  TRP L CZ3 1 
ATOM   1876 C CH2 . TRP B 2 37  ? 24.42783  20.55267 31.67371  1.000 40.42509  ? 35  TRP L CH2 1 
ATOM   1877 N N   . TYR B 2 38  ? 20.37432  23.51592 26.36034  1.000 26.42592  ? 36  TYR L N   1 
ATOM   1878 C CA  . TYR B 2 38  ? 19.07225  23.65839 25.72558  1.000 23.61267  ? 36  TYR L CA  1 
ATOM   1879 C C   . TYR B 2 38  ? 17.97346  23.25311 26.70605  1.000 25.53742  ? 36  TYR L C   1 
ATOM   1880 O O   . TYR B 2 38  ? 18.18642  22.42927 27.60199  1.000 24.32619  ? 36  TYR L O   1 
ATOM   1881 C CB  . TYR B 2 38  ? 18.99458  22.81062 24.44779  1.000 22.13621  ? 36  TYR L CB  1 
ATOM   1882 C CG  . TYR B 2 38  ? 19.52812  23.51969 23.22894  1.000 22.55207  ? 36  TYR L CG  1 
ATOM   1883 C CD1 . TYR B 2 38  ? 20.89465  23.59257 22.98335  1.000 29.37829  ? 36  TYR L CD1 1 
ATOM   1884 C CD2 . TYR B 2 38  ? 18.66453  24.13801 22.33248  1.000 21.78481  ? 36  TYR L CD2 1 
ATOM   1885 C CE1 . TYR B 2 38  ? 21.38277  24.25618 21.86745  1.000 25.08967  ? 36  TYR L CE1 1 
ATOM   1886 C CE2 . TYR B 2 38  ? 19.14275  24.79694 21.21890  1.000 25.58108  ? 36  TYR L CE2 1 
ATOM   1887 C CZ  . TYR B 2 38  ? 20.50447  24.85543 20.99461  1.000 26.00206  ? 36  TYR L CZ  1 
ATOM   1888 O OH  . TYR B 2 38  ? 20.98461  25.51717 19.87977  1.000 28.72419  ? 36  TYR L OH  1 
ATOM   1889 N N   . GLN B 2 39  ? 16.79801  23.84941 26.54154  1.000 27.29696  ? 37  GLN L N   1 
ATOM   1890 C CA  . GLN B 2 39  ? 15.63509  23.52891 27.35896  1.000 23.14198  ? 37  GLN L CA  1 
ATOM   1891 C C   . GLN B 2 39  ? 14.50204  23.12460 26.42991  1.000 24.22117  ? 37  GLN L C   1 
ATOM   1892 O O   . GLN B 2 39  ? 14.22003  23.82858 25.45858  1.000 21.21711  ? 37  GLN L O   1 
ATOM   1893 C CB  . GLN B 2 39  ? 15.22761  24.72791 28.21651  1.000 21.58900  ? 37  GLN L CB  1 
ATOM   1894 C CG  . GLN B 2 39  ? 13.89475  24.62250 28.92073  1.000 23.07944  ? 37  GLN L CG  1 
ATOM   1895 C CD  . GLN B 2 39  ? 13.39051  25.97765 29.38709  1.000 26.52383  ? 37  GLN L CD  1 
ATOM   1896 O OE1 . GLN B 2 39  ? 13.01923  26.82735 28.58110  1.000 21.28966  ? 37  GLN L OE1 1 
ATOM   1897 N NE2 . GLN B 2 39  ? 13.37909  26.18765 30.69569  1.000 25.99042  ? 37  GLN L NE2 1 
ATOM   1898 N N   . GLN B 2 40  ? 13.83931  22.00663 26.72546  1.000 20.74178  ? 38  GLN L N   1 
ATOM   1899 C CA  . GLN B 2 40  ? 12.72451  21.56526 25.89598  1.000 21.72641  ? 38  GLN L CA  1 
ATOM   1900 C C   . GLN B 2 40  ? 11.50196  21.33909 26.76777  1.000 19.16631  ? 38  GLN L C   1 
ATOM   1901 O O   . GLN B 2 40  ? 11.50426  20.45341 27.62989  1.000 23.15065  ? 38  GLN L O   1 
ATOM   1902 C CB  . GLN B 2 40  ? 13.07181  20.29463 25.11918  1.000 19.39974  ? 38  GLN L CB  1 
ATOM   1903 C CG  . GLN B 2 40  ? 11.96736  19.90856 24.14959  1.000 22.60519  ? 38  GLN L CG  1 
ATOM   1904 C CD  . GLN B 2 40  ? 12.35586  18.73771 23.27089  1.000 22.79766  ? 38  GLN L CD  1 
ATOM   1905 O OE1 . GLN B 2 40  ? 13.01431  17.80531 23.72735  1.000 26.65656  ? 38  GLN L OE1 1 
ATOM   1906 N NE2 . GLN B 2 40  ? 11.96416  18.78819 21.99963  1.000 19.07915  ? 38  GLN L NE2 1 
ATOM   1907 N N   . LYS B 2 41  ? 10.47584  22.13478 26.54022  1.000 21.80218  ? 39  LYS L N   1 
ATOM   1908 C CA  . LYS B 2 41  ? 9.17254   22.02947 27.16305  1.000 26.38126  ? 39  LYS L CA  1 
ATOM   1909 C C   . LYS B 2 41  ? 8.25839   21.14636 26.32728  1.000 28.44267  ? 39  LYS L C   1 
ATOM   1910 O O   . LYS B 2 41  ? 8.53696   20.87710 25.15138  1.000 27.65201  ? 39  LYS L O   1 
ATOM   1911 C CB  . LYS B 2 41  ? 8.58407   23.42426 27.35267  1.000 27.30644  ? 39  LYS L CB  1 
ATOM   1912 C CG  . LYS B 2 41  ? 9.40534   24.22338 28.34579  1.000 29.22948  ? 39  LYS L CG  1 
ATOM   1913 C CD  . LYS B 2 41  ? 8.91308   25.64379 28.53690  1.000 31.55873  ? 39  LYS L CD  1 
ATOM   1914 C CE  . LYS B 2 41  ? 9.89822   26.40372 29.41008  1.000 31.65684  ? 39  LYS L CE  1 
ATOM   1915 N NZ  . LYS B 2 41  ? 9.38900   27.71717 29.90284  1.000 34.67796  ? 39  LYS L NZ  1 
ATOM   1916 N N   . PRO B 2 42  ? 7.17298   20.64690 26.91550  1.000 30.93607  ? 40  PRO L N   1 
ATOM   1917 C CA  . PRO B 2 42  ? 6.36620   19.62549 26.22840  1.000 36.26922  ? 40  PRO L CA  1 
ATOM   1918 C C   . PRO B 2 42  ? 5.81994   20.10233 24.88883  1.000 30.89090  ? 40  PRO L C   1 
ATOM   1919 O O   . PRO B 2 42  ? 5.23421   21.17969 24.77669  1.000 37.33388  ? 40  PRO L O   1 
ATOM   1920 C CB  . PRO B 2 42  ? 5.24593   19.33847 27.23361  1.000 38.32064  ? 40  PRO L CB  1 
ATOM   1921 C CG  . PRO B 2 42  ? 5.89287   19.59609 28.55850  1.000 32.38612  ? 40  PRO L CG  1 
ATOM   1922 C CD  . PRO B 2 42  ? 6.77776   20.78862 28.32992  1.000 30.36929  ? 40  PRO L CD  1 
ATOM   1923 N N   . GLY B 2 43  ? 6.03323   19.29082 23.86105  1.000 34.68351  ? 41  GLY L N   1 
ATOM   1924 C CA  . GLY B 2 43  ? 5.51559   19.59330 22.53988  1.000 39.49285  ? 41  GLY L CA  1 
ATOM   1925 C C   . GLY B 2 43  ? 6.11450   20.82852 21.89316  1.000 48.31344  ? 41  GLY L C   1 
ATOM   1926 O O   . GLY B 2 43  ? 5.57717   21.33619 20.90254  1.000 41.29882  ? 41  GLY L O   1 
ATOM   1927 N N   . LYS B 2 44  ? 7.22918   21.31732 22.43296  1.000 33.32034  ? 42  LYS L N   1 
ATOM   1928 C CA  . LYS B 2 44  ? 7.92128   22.46701 21.87772  1.000 29.63611  ? 42  LYS L CA  1 
ATOM   1929 C C   . LYS B 2 44  ? 9.29041   22.05247 21.35600  1.000 24.12948  ? 42  LYS L C   1 
ATOM   1930 O O   . LYS B 2 44  ? 9.84633   21.01894 21.73961  1.000 29.06162  ? 42  LYS L O   1 
ATOM   1931 C CB  . LYS B 2 44  ? 8.07943   23.57634 22.92903  1.000 36.98760  ? 42  LYS L CB  1 
ATOM   1932 C CG  . LYS B 2 44  ? 6.77831   24.10929 23.49819  1.000 35.35070  ? 42  LYS L CG  1 
ATOM   1933 C CD  . LYS B 2 44  ? 6.08980   25.04252 22.50343  1.000 53.41529  ? 42  LYS L CD  1 
ATOM   1934 C CE  . LYS B 2 44  ? 4.77176   25.57354 23.04799  1.000 52.89320  ? 42  LYS L CE  1 
ATOM   1935 N NZ  . LYS B 2 44  ? 3.88698   26.10275 21.96389  1.000 49.70438  ? 42  LYS L NZ  1 
ATOM   1936 N N   . ALA B 2 45  ? 9.83002   22.88413 20.47484  1.000 27.46235  ? 43  ALA L N   1 
ATOM   1937 C CA  . ALA B 2 45  ? 11.18084  22.68995 19.99222  1.000 29.22334  ? 43  ALA L CA  1 
ATOM   1938 C C   . ALA B 2 45  ? 12.18158  23.05849 21.08874  1.000 30.13428  ? 43  ALA L C   1 
ATOM   1939 O O   . ALA B 2 45  ? 11.87030  23.85348 21.98411  1.000 29.22680  ? 43  ALA L O   1 
ATOM   1940 C CB  . ALA B 2 45  ? 11.42821  23.53814 18.74386  1.000 27.92330  ? 43  ALA L CB  1 
ATOM   1941 N N   . PRO B 2 46  ? 13.38392  22.48097 21.05185  1.000 26.76154  ? 44  PRO L N   1 
ATOM   1942 C CA  . PRO B 2 46  ? 14.39590  22.83744 22.05041  1.000 24.21344  ? 44  PRO L CA  1 
ATOM   1943 C C   . PRO B 2 46  ? 14.75842  24.30649 21.92664  1.000 32.58087  ? 44  PRO L C   1 
ATOM   1944 O O   . PRO B 2 46  ? 14.74946  24.88250 20.83765  1.000 23.31842  ? 44  PRO L O   1 
ATOM   1945 C CB  . PRO B 2 46  ? 15.58805  21.93854 21.70043  1.000 23.48841  ? 44  PRO L CB  1 
ATOM   1946 C CG  . PRO B 2 46  ? 15.01681  20.84324 20.84403  1.000 28.10348  ? 44  PRO L CG  1 
ATOM   1947 C CD  . PRO B 2 46  ? 13.86702  21.46078 20.10414  1.000 22.74442  ? 44  PRO L CD  1 
ATOM   1948 N N   . LYS B 2 47  ? 15.08116  24.91433 23.06110  1.000 27.75606  ? 45  LYS L N   1 
ATOM   1949 C CA  . LYS B 2 47  ? 15.38623  26.33657 23.11036  1.000 26.88277  ? 45  LYS L CA  1 
ATOM   1950 C C   . LYS B 2 47  ? 16.71958  26.52352 23.82210  1.000 25.82580  ? 45  LYS L C   1 
ATOM   1951 O O   . LYS B 2 47  ? 16.93528  25.96585 24.90082  1.000 23.68363  ? 45  LYS L O   1 
ATOM   1952 C CB  . LYS B 2 47  ? 14.25161  27.08833 23.81171  1.000 24.89014  ? 45  LYS L CB  1 
ATOM   1953 C CG  . LYS B 2 47  ? 14.57315  28.49726 24.28852  1.000 36.58612  ? 45  LYS L CG  1 
ATOM   1954 C CD  . LYS B 2 47  ? 13.59209  28.89357 25.41057  1.000 39.31398  ? 45  LYS L CD  1 
ATOM   1955 C CE  . LYS B 2 47  ? 13.68186  30.36432 25.78304  1.000 44.61073  ? 45  LYS L CE  1 
ATOM   1956 N NZ  . LYS B 2 47  ? 12.80591  30.68101 26.96408  1.000 48.42379  ? 45  LYS L NZ  1 
ATOM   1957 N N   . ARG B 2 48  ? 17.62412  27.28164 23.21036  1.000 27.80386  ? 46  ARG L N   1 
ATOM   1958 C CA  . ARG B 2 48  ? 18.94790  27.46510 23.79038  1.000 24.86375  ? 46  ARG L CA  1 
ATOM   1959 C C   . ARG B 2 48  ? 18.88876  28.48120 24.93014  1.000 23.10520  ? 46  ARG L C   1 
ATOM   1960 O O   . ARG B 2 48  ? 18.27716  29.54851 24.80060  1.000 28.76073  ? 46  ARG L O   1 
ATOM   1961 C CB  . ARG B 2 48  ? 19.95769  27.91097 22.72537  1.000 25.98157  ? 46  ARG L CB  1 
ATOM   1962 C CG  . ARG B 2 48  ? 21.41943  27.85441 23.19654  1.000 25.23187  ? 46  ARG L CG  1 
ATOM   1963 C CD  . ARG B 2 48  ? 22.39744  28.49595 22.18322  1.000 24.77638  ? 46  ARG L CD  1 
ATOM   1964 N NE  . ARG B 2 48  ? 22.00042  29.85771 21.84488  1.000 31.42284  ? 46  ARG L NE  1 
ATOM   1965 C CZ  . ARG B 2 48  ? 22.78396  30.74103 21.23909  1.000 38.77727  ? 46  ARG L CZ  1 
ATOM   1966 N NH1 . ARG B 2 48  ? 24.04214  30.45723 20.93728  1.000 27.88530  ? 46  ARG L NH1 1 
ATOM   1967 N NH2 . ARG B 2 48  ? 22.28812  31.93422 20.91679  1.000 33.31881  ? 46  ARG L NH2 1 
ATOM   1968 N N   . LEU B 2 49  ? 19.51152  28.13484 26.05322  1.000 22.35856  ? 47  LEU L N   1 
ATOM   1969 C CA  . LEU B 2 49  ? 19.60593  29.01861 27.21214  1.000 31.92967  ? 47  LEU L CA  1 
ATOM   1970 C C   . LEU B 2 49  ? 20.98874  29.63964 27.36096  1.000 30.14147  ? 47  LEU L C   1 
ATOM   1971 O O   . LEU B 2 49  ? 21.10737  30.84758 27.59006  1.000 28.96420  ? 47  LEU L O   1 
ATOM   1972 C CB  . LEU B 2 49  ? 19.27012  28.25151 28.49176  1.000 29.95610  ? 47  LEU L CB  1 
ATOM   1973 C CG  . LEU B 2 49  ? 17.95807  27.46876 28.55654  1.000 25.76047  ? 47  LEU L CG  1 
ATOM   1974 C CD1 . LEU B 2 49  ? 17.99533  26.62042 29.80507  1.000 31.76861  ? 47  LEU L CD1 1 
ATOM   1975 C CD2 . LEU B 2 49  ? 16.77236  28.40001 28.57734  1.000 26.37877  ? 47  LEU L CD2 1 
ATOM   1976 N N   . ILE B 2 50  ? 22.03219  28.81791 27.25236  1.000 35.07163  ? 48  ILE L N   1 
ATOM   1977 C CA  . ILE B 2 50  ? 23.41219  29.19597 27.53541  1.000 33.79290  ? 48  ILE L CA  1 
ATOM   1978 C C   . ILE B 2 50  ? 24.27418  28.74132 26.36741  1.000 39.32282  ? 48  ILE L C   1 
ATOM   1979 O O   . ILE B 2 50  ? 24.02969  27.68087 25.78605  1.000 35.12944  ? 48  ILE L O   1 
ATOM   1980 C CB  . ILE B 2 50  ? 23.91712  28.55001 28.84112  1.000 38.31836  ? 48  ILE L CB  1 
ATOM   1981 C CG1 . ILE B 2 50  ? 23.00302  28.89391 30.02024  1.000 33.02833  ? 48  ILE L CG1 1 
ATOM   1982 C CG2 . ILE B 2 50  ? 25.36539  28.94822 29.11866  1.000 42.91784  ? 48  ILE L CG2 1 
ATOM   1983 C CD1 . ILE B 2 50  ? 23.09822  30.31967 30.46216  1.000 35.92000  ? 48  ILE L CD1 1 
ATOM   1984 N N   . TYR B 2 51  ? 25.28095  29.53481 26.01944  1.000 37.47550  ? 49  TYR L N   1 
ATOM   1985 C CA  . TYR B 2 51  ? 26.24902  29.12543 25.01216  1.000 37.44033  ? 49  TYR L CA  1 
ATOM   1986 C C   . TYR B 2 51  ? 27.64412  29.50142 25.48696  1.000 40.22693  ? 49  TYR L C   1 
ATOM   1987 O O   . TYR B 2 51  ? 27.81218  30.37511 26.33960  1.000 39.07408  ? 49  TYR L O   1 
ATOM   1988 C CB  . TYR B 2 51  ? 25.96008  29.75794 23.64915  1.000 33.82349  ? 49  TYR L CB  1 
ATOM   1989 C CG  . TYR B 2 51  ? 26.01289  31.27433 23.61074  1.000 41.90479  ? 49  TYR L CG  1 
ATOM   1990 C CD1 . TYR B 2 51  ? 24.87978  32.03386 23.87666  1.000 41.56111  ? 49  TYR L CD1 1 
ATOM   1991 C CD2 . TYR B 2 51  ? 27.19203  31.94507 23.28030  1.000 42.18388  ? 49  TYR L CD2 1 
ATOM   1992 C CE1 . TYR B 2 51  ? 24.91617  33.42313 23.83006  1.000 41.39595  ? 49  TYR L CE1 1 
ATOM   1993 C CE2 . TYR B 2 51  ? 27.23894  33.33424 23.23179  1.000 42.77217  ? 49  TYR L CE2 1 
ATOM   1994 C CZ  . TYR B 2 51  ? 26.09876  34.06629 23.50389  1.000 49.81324  ? 49  TYR L CZ  1 
ATOM   1995 O OH  . TYR B 2 51  ? 26.13386  35.44459 23.45125  1.000 52.27441  ? 49  TYR L OH  1 
ATOM   1996 N N   . ALA B 2 52  ? 28.64768  28.81746 24.93782  1.000 39.79140  ? 50  ALA L N   1 
ATOM   1997 C CA  . ALA B 2 52  ? 30.03642  29.06180 25.31730  1.000 41.36943  ? 50  ALA L CA  1 
ATOM   1998 C C   . ALA B 2 52  ? 30.21827  28.88181 26.81681  1.000 46.51234  ? 50  ALA L C   1 
ATOM   1999 O O   . ALA B 2 52  ? 30.84207  29.70321 27.48722  1.000 48.70445  ? 50  ALA L O   1 
ATOM   2000 C CB  . ALA B 2 52  ? 30.49919  30.45200 24.87694  1.000 38.28169  ? 50  ALA L CB  1 
ATOM   2001 N N   . ILE B 2 53  ? 29.61672  27.81934 27.34368  1.000 40.05139  ? 51  ILE L N   1 
ATOM   2002 C CA  . ILE B 2 53  ? 29.70032  27.41350 28.74239  1.000 46.66589  ? 51  ILE L CA  1 
ATOM   2003 C C   . ILE B 2 53  ? 28.94817  28.35565 29.67668  1.000 42.95947  ? 51  ILE L C   1 
ATOM   2004 O O   . ILE B 2 53  ? 28.26133  27.89263 30.59156  1.000 40.91296  ? 51  ILE L O   1 
ATOM   2005 C CB  . ILE B 2 53  ? 31.16414  27.26263 29.18995  1.000 44.53804  ? 51  ILE L CB  1 
ATOM   2006 C CG1 . ILE B 2 53  ? 31.86231  26.22674 28.31467  1.000 51.78593  ? 51  ILE L CG1 1 
ATOM   2007 C CG2 . ILE B 2 53  ? 31.22532  26.86568 30.65848  1.000 42.03609  ? 51  ILE L CG2 1 
ATOM   2008 C CD1 . ILE B 2 53  ? 33.35520  26.17948 28.49299  1.000 59.57675  ? 51  ILE L CD1 1 
ATOM   2009 N N   . ALA B 2 54  ? 29.07039  29.67984 29.48014  1.000 41.77846  ? 52  ALA L N   1 
ATOM   2010 C CA  . ALA B 2 54  ? 28.54710  30.59908 30.48396  1.000 37.10612  ? 52  ALA L CA  1 
ATOM   2011 C C   . ALA B 2 54  ? 27.83885  31.83286 29.94530  1.000 37.12053  ? 52  ALA L C   1 
ATOM   2012 O O   . ALA B 2 54  ? 27.34568  32.62798 30.75341  1.000 39.38799  ? 52  ALA L O   1 
ATOM   2013 C CB  . ALA B 2 54  ? 29.67402  31.05228 31.43011  1.000 46.82783  ? 52  ALA L CB  1 
ATOM   2014 N N   . SER B 2 55  ? 27.76406  32.02979 28.63348  1.000 28.49760  ? 53  SER L N   1 
ATOM   2015 C CA  . SER B 2 55  ? 27.06403  33.19196 28.10652  1.000 38.89525  ? 53  SER L CA  1 
ATOM   2016 C C   . SER B 2 55  ? 25.56976  32.92018 28.05147  1.000 41.92333  ? 53  SER L C   1 
ATOM   2017 O O   . SER B 2 55  ? 25.12897  31.88328 27.54782  1.000 42.68573  ? 53  SER L O   1 
ATOM   2018 C CB  . SER B 2 55  ? 27.57203  33.57164 26.71757  1.000 35.12563  ? 53  SER L CB  1 
ATOM   2019 O OG  . SER B 2 55  ? 28.83808  34.19143 26.78761  1.000 50.30606  ? 53  SER L OG  1 
ATOM   2020 N N   . LEU B 2 56  ? 24.80041  33.87634 28.53491  1.000 32.38203  ? 54  LEU L N   1 
ATOM   2021 C CA  . LEU B 2 56  ? 23.36122  33.76619 28.65617  1.000 28.17597  ? 54  LEU L CA  1 
ATOM   2022 C C   . LEU B 2 56  ? 22.71187  34.48694 27.48548  1.000 30.22609  ? 54  LEU L C   1 
ATOM   2023 O O   . LEU B 2 56  ? 22.96418  35.67672 27.27131  1.000 32.92599  ? 54  LEU L O   1 
ATOM   2024 C CB  . LEU B 2 56  ? 22.91748  34.37558 29.98213  1.000 31.34002  ? 54  LEU L CB  1 
ATOM   2025 C CG  . LEU B 2 56  ? 21.41679  34.47080 30.19000  1.000 29.88318  ? 54  LEU L CG  1 
ATOM   2026 C CD1 . LEU B 2 56  ? 20.86644  33.06408 30.35638  1.000 25.74015  ? 54  LEU L CD1 1 
ATOM   2027 C CD2 . LEU B 2 56  ? 21.10108  35.34026 31.40805  1.000 25.59855  ? 54  LEU L CD2 1 
ATOM   2028 N N   . TYR B 2 57  ? 21.88380  33.77399 26.72510  1.000 29.89317  ? 55  TYR L N   1 
ATOM   2029 C CA  . TYR B 2 57  ? 21.19320  34.40280 25.60926  1.000 30.34040  ? 55  TYR L CA  1 
ATOM   2030 C C   . TYR B 2 57  ? 20.22088  35.46645 26.11123  1.000 32.19061  ? 55  TYR L C   1 
ATOM   2031 O O   . TYR B 2 57  ? 19.55354  35.28998 27.13645  1.000 31.48323  ? 55  TYR L O   1 
ATOM   2032 C CB  . TYR B 2 57  ? 20.44860  33.35468 24.78023  1.000 30.38939  ? 55  TYR L CB  1 
ATOM   2033 C CG  . TYR B 2 57  ? 19.69526  33.94805 23.60840  1.000 31.70026  ? 55  TYR L CG  1 
ATOM   2034 C CD1 . TYR B 2 57  ? 20.37286  34.58703 22.57911  1.000 29.58167  ? 55  TYR L CD1 1 
ATOM   2035 C CD2 . TYR B 2 57  ? 18.30904  33.86061 23.52749  1.000 30.51839  ? 55  TYR L CD2 1 
ATOM   2036 C CE1 . TYR B 2 57  ? 19.69266  35.12666 21.50526  1.000 34.31876  ? 55  TYR L CE1 1 
ATOM   2037 C CE2 . TYR B 2 57  ? 17.61990  34.40473 22.45393  1.000 33.36627  ? 55  TYR L CE2 1 
ATOM   2038 C CZ  . TYR B 2 57  ? 18.32321  35.03105 21.44896  1.000 33.33206  ? 55  TYR L CZ  1 
ATOM   2039 O OH  . TYR B 2 57  ? 17.65390  35.56856 20.37761  1.000 51.02213  ? 55  TYR L OH  1 
ATOM   2040 N N   . SER B 2 58  ? 20.13685  36.57088 25.36166  1.000 27.69231  ? 56  SER L N   1 
ATOM   2041 C CA  . SER B 2 58  ? 19.38798  37.75047 25.79944  1.000 31.37861  ? 56  SER L CA  1 
ATOM   2042 C C   . SER B 2 58  ? 17.90207  37.46909 25.98778  1.000 25.76181  ? 56  SER L C   1 
ATOM   2043 O O   . SER B 2 58  ? 17.22569  38.19340 26.72328  1.000 28.87550  ? 56  SER L O   1 
ATOM   2044 C CB  . SER B 2 58  ? 19.56532  38.87635 24.78292  1.000 29.31200  ? 56  SER L CB  1 
ATOM   2045 O OG  . SER B 2 58  ? 20.92827  39.23574 24.69094  1.000 42.94332  ? 56  SER L OG  1 
ATOM   2046 N N   . GLY B 2 59  ? 17.36187  36.44620 25.31290  1.000 28.09184  ? 57  GLY L N   1 
ATOM   2047 C CA  . GLY B 2 59  ? 15.95859  36.11270 25.50087  1.000 25.75060  ? 57  GLY L CA  1 
ATOM   2048 C C   . GLY B 2 59  ? 15.62662  35.29073 26.72961  1.000 28.56156  ? 57  GLY L C   1 
ATOM   2049 O O   . GLY B 2 59  ? 14.44905  35.01900 26.97055  1.000 27.15776  ? 57  GLY L O   1 
ATOM   2050 N N   . VAL B 2 60  ? 16.62410  34.92415 27.53352  1.000 24.13519  ? 58  VAL L N   1 
ATOM   2051 C CA  . VAL B 2 60  ? 16.49605  33.95479 28.62654  1.000 22.97419  ? 58  VAL L CA  1 
ATOM   2052 C C   . VAL B 2 60  ? 16.64207  34.66780 29.97082  1.000 29.45733  ? 58  VAL L C   1 
ATOM   2053 O O   . VAL B 2 60  ? 17.49241  35.56043 30.09672  1.000 29.92820  ? 58  VAL L O   1 
ATOM   2054 C CB  . VAL B 2 60  ? 17.55186  32.83927 28.47195  1.000 25.46409  ? 58  VAL L CB  1 
ATOM   2055 C CG1 . VAL B 2 60  ? 17.56840  31.89617 29.66892  1.000 27.23276  ? 58  VAL L CG1 1 
ATOM   2056 C CG2 . VAL B 2 60  ? 17.33174  32.05880 27.16300  1.000 27.71047  ? 58  VAL L CG2 1 
ATOM   2057 N N   . PRO B 2 61  ? 15.87594  34.29844 31.00202  1.000 28.30347  ? 59  PRO L N   1 
ATOM   2058 C CA  . PRO B 2 61  ? 16.00587  34.97516 32.30256  1.000 28.44923  ? 59  PRO L CA  1 
ATOM   2059 C C   . PRO B 2 61  ? 17.36980  34.74362 32.93842  1.000 28.52667  ? 59  PRO L C   1 
ATOM   2060 O O   . PRO B 2 61  ? 18.00663  33.71010 32.74291  1.000 24.93745  ? 59  PRO L O   1 
ATOM   2061 C CB  . PRO B 2 61  ? 14.88984  34.34228 33.15087  1.000 30.67204  ? 59  PRO L CB  1 
ATOM   2062 C CG  . PRO B 2 61  ? 13.91710  33.79705 32.17052  1.000 31.53770  ? 59  PRO L CG  1 
ATOM   2063 C CD  . PRO B 2 61  ? 14.74405  33.35127 30.98776  1.000 28.61922  ? 59  PRO L CD  1 
ATOM   2064 N N   . SER B 2 62  ? 17.80490  35.72189 33.73606  1.000 31.88261  ? 60  SER L N   1 
ATOM   2065 C CA  . SER B 2 62  ? 19.13272  35.67482 34.34738  1.000 32.16141  ? 60  SER L CA  1 
ATOM   2066 C C   . SER B 2 62  ? 19.25542  34.65621 35.47667  1.000 37.22508  ? 60  SER L C   1 
ATOM   2067 O O   . SER B 2 62  ? 20.37572  34.41282 35.94441  1.000 31.25764  ? 60  SER L O   1 
ATOM   2068 C CB  . SER B 2 62  ? 19.52330  37.06485 34.86607  1.000 38.63556  ? 60  SER L CB  1 
ATOM   2069 O OG  . SER B 2 62  ? 18.64877  37.47933 35.89974  1.000 42.10748  ? 60  SER L OG  1 
ATOM   2070 N N   . ARG B 2 63  ? 18.15908  34.04092 35.92415  1.000 26.70098  ? 61  ARG L N   1 
ATOM   2071 C CA  . ARG B 2 63  ? 18.32651  32.95216 36.87929  1.000 29.27814  ? 61  ARG L CA  1 
ATOM   2072 C C   . ARG B 2 63  ? 19.00341  31.72326 36.27226  1.000 33.11419  ? 61  ARG L C   1 
ATOM   2073 O O   . ARG B 2 63  ? 19.36830  30.80709 37.01566  1.000 32.87275  ? 61  ARG L O   1 
ATOM   2074 C CB  . ARG B 2 63  ? 16.98077  32.55304 37.48090  1.000 33.32441  ? 61  ARG L CB  1 
ATOM   2075 C CG  . ARG B 2 63  ? 16.11822  31.70277 36.57089  1.000 39.43403  ? 61  ARG L CG  1 
ATOM   2076 C CD  . ARG B 2 63  ? 15.01447  30.99845 37.37232  1.000 42.96185  ? 61  ARG L CD  1 
ATOM   2077 N NE  . ARG B 2 63  ? 13.91202  30.61548 36.50878  1.000 31.27082  ? 61  ARG L NE  1 
ATOM   2078 C CZ  . ARG B 2 63  ? 13.04284  31.48078 36.00816  1.000 33.18293  ? 61  ARG L CZ  1 
ATOM   2079 N NH1 . ARG B 2 63  ? 13.07861  32.76099 36.33760  1.000 32.79232  ? 61  ARG L NH1 1 
ATOM   2080 N NH2 . ARG B 2 63  ? 12.12638  31.05512 35.14495  1.000 38.55773  ? 61  ARG L NH2 1 
ATOM   2081 N N   . PHE B 2 64  ? 19.17845  31.66204 34.95573  1.000 28.95197  ? 62  PHE L N   1 
ATOM   2082 C CA  . PHE B 2 64  ? 19.96901  30.59157 34.36572  1.000 30.32406  ? 62  PHE L CA  1 
ATOM   2083 C C   . PHE B 2 64  ? 21.42306  31.03938 34.27211  1.000 30.06744  ? 62  PHE L C   1 
ATOM   2084 O O   . PHE B 2 64  ? 21.69933  32.19392 33.94394  1.000 32.89070  ? 62  PHE L O   1 
ATOM   2085 C CB  . PHE B 2 64  ? 19.42529  30.21404 32.98161  1.000 27.40898  ? 62  PHE L CB  1 
ATOM   2086 C CG  . PHE B 2 64  ? 18.05266  29.58138 33.02135  1.000 25.95396  ? 62  PHE L CG  1 
ATOM   2087 C CD1 . PHE B 2 64  ? 16.91111  30.36900 33.01885  1.000 25.39905  ? 62  PHE L CD1 1 
ATOM   2088 C CD2 . PHE B 2 64  ? 17.91094  28.20484 33.08817  1.000 24.68377  ? 62  PHE L CD2 1 
ATOM   2089 C CE1 . PHE B 2 64  ? 15.64170  29.79760 33.06363  1.000 27.00854  ? 62  PHE L CE1 1 
ATOM   2090 C CE2 . PHE B 2 64  ? 16.64452  27.62511 33.14753  1.000 23.39958  ? 62  PHE L CE2 1 
ATOM   2091 C CZ  . PHE B 2 64  ? 15.51144  28.42638 33.12764  1.000 20.14408  ? 62  PHE L CZ  1 
ATOM   2092 N N   . SER B 2 65  ? 22.34726  30.12136 34.56014  1.000 29.56377  ? 63  SER L N   1 
ATOM   2093 C CA  . SER B 2 65  ? 23.77472  30.39676 34.43547  1.000 38.32731  ? 63  SER L CA  1 
ATOM   2094 C C   . SER B 2 65  ? 24.52867  29.08961 34.24384  1.000 37.00788  ? 63  SER L C   1 
ATOM   2095 O O   . SER B 2 65  ? 24.12880  28.04505 34.76797  1.000 38.01984  ? 63  SER L O   1 
ATOM   2096 C CB  . SER B 2 65  ? 24.32177  31.11996 35.67113  1.000 33.39107  ? 63  SER L CB  1 
ATOM   2097 O OG  . SER B 2 65  ? 24.40344  30.21641 36.76022  1.000 41.14252  ? 63  SER L OG  1 
ATOM   2098 N N   . GLY B 2 66  ? 25.64500  29.16386 33.51970  1.000 39.35886  ? 64  GLY L N   1 
ATOM   2099 C CA  . GLY B 2 66  ? 26.48541  27.99204 33.34335  1.000 41.91644  ? 64  GLY L CA  1 
ATOM   2100 C C   . GLY B 2 66  ? 27.91635  28.14856 33.82932  1.000 43.86446  ? 64  GLY L C   1 
ATOM   2101 O O   . GLY B 2 66  ? 28.40855  29.26934 33.98038  1.000 44.56582  ? 64  GLY L O   1 
ATOM   2102 N N   . SER B 2 67  ? 28.59482  27.02756 34.06754  1.000 50.12427  ? 65  SER L N   1 
ATOM   2103 C CA  . SER B 2 67  ? 29.99883  27.02195 34.46243  1.000 49.32612  ? 65  SER L CA  1 
ATOM   2104 C C   . SER B 2 67  ? 30.59363  25.66141 34.12040  1.000 52.08875  ? 65  SER L C   1 
ATOM   2105 O O   . SER B 2 67  ? 29.88659  24.73586 33.71652  1.000 58.80217  ? 65  SER L O   1 
ATOM   2106 C CB  . SER B 2 67  ? 30.16237  27.33068 35.95376  1.000 48.16288  ? 65  SER L CB  1 
ATOM   2107 O OG  . SER B 2 67  ? 29.52472  26.34541 36.74257  1.000 57.64403  ? 65  SER L OG  1 
ATOM   2108 N N   . GLY B 2 68  ? 31.90645  25.54896 34.28669  1.000 53.63221  ? 66  GLY L N   1 
ATOM   2109 C CA  . GLY B 2 68  ? 32.61806  24.30971 34.04049  1.000 57.81159  ? 66  GLY L CA  1 
ATOM   2110 C C   . GLY B 2 68  ? 33.88427  24.52572 33.23430  1.000 61.72746  ? 66  GLY L C   1 
ATOM   2111 O O   . GLY B 2 68  ? 34.12689  25.59009 32.66394  1.000 64.35101  ? 66  GLY L O   1 
ATOM   2112 N N   . SER B 2 69  ? 34.69887  23.47076 33.18952  1.000 65.95562  ? 67  SER L N   1 
ATOM   2113 C CA  . SER B 2 69  ? 35.98890  23.54559 32.51326  1.000 71.74022  ? 67  SER L CA  1 
ATOM   2114 C C   . SER B 2 69  ? 36.34090  22.20821 31.87711  1.000 65.46495  ? 67  SER L C   1 
ATOM   2115 O O   . SER B 2 69  ? 36.26866  21.16318 32.53307  1.000 63.35989  ? 67  SER L O   1 
ATOM   2116 C CB  . SER B 2 69  ? 37.09574  23.96273 33.49012  1.000 73.81107  ? 67  SER L CB  1 
ATOM   2117 O OG  . SER B 2 69  ? 36.74450  25.13602 34.20657  1.000 78.23679  ? 67  SER L OG  1 
ATOM   2118 N N   . GLY B 2 70  ? 36.72733  22.25595 30.60453  1.000 59.38313  ? 68  GLY L N   1 
ATOM   2119 C CA  . GLY B 2 70  ? 37.33327  21.12512 29.93205  1.000 62.29902  ? 68  GLY L CA  1 
ATOM   2120 C C   . GLY B 2 70  ? 36.38591  20.01829 29.52397  1.000 62.52018  ? 68  GLY L C   1 
ATOM   2121 O O   . GLY B 2 70  ? 36.01305  19.91335 28.34869  1.000 52.00121  ? 68  GLY L O   1 
ATOM   2122 N N   . THR B 2 71  ? 36.01218  19.16795 30.48917  1.000 65.20368  ? 69  THR L N   1 
ATOM   2123 C CA  . THR B 2 71  ? 35.15287  18.01845 30.23439  1.000 64.64527  ? 69  THR L CA  1 
ATOM   2124 C C   . THR B 2 71  ? 33.96124  17.92133 31.18110  1.000 58.96775  ? 69  THR L C   1 
ATOM   2125 O O   . THR B 2 71  ? 33.12142  17.03435 30.99331  1.000 67.14331  ? 69  THR L O   1 
ATOM   2126 C CB  . THR B 2 71  ? 35.95065  16.69898 30.32164  1.000 62.82485  ? 69  THR L CB  1 
ATOM   2127 O OG1 . THR B 2 71  ? 36.47181  16.52746 31.65071  1.000 61.53451  ? 69  THR L OG1 1 
ATOM   2128 C CG2 . THR B 2 71  ? 37.09363  16.67243 29.31140  1.000 54.40437  ? 69  THR L CG2 1 
ATOM   2129 N N   . ASP B 2 72  ? 33.86965  18.77720 32.19650  1.000 58.62923  ? 70  ASP L N   1 
ATOM   2130 C CA  . ASP B 2 72  ? 32.75733  18.76658 33.13986  1.000 59.77993  ? 70  ASP L CA  1 
ATOM   2131 C C   . ASP B 2 72  ? 32.11290  20.14458 33.16369  1.000 60.90360  ? 70  ASP L C   1 
ATOM   2132 O O   . ASP B 2 72  ? 32.81441  21.15832 33.24303  1.000 60.17833  ? 70  ASP L O   1 
ATOM   2133 C CB  . ASP B 2 72  ? 33.21613  18.36969 34.54704  1.000 54.64741  ? 70  ASP L CB  1 
ATOM   2134 C CG  . ASP B 2 72  ? 33.58760  16.89427 34.65593  1.000 65.46015  ? 70  ASP L CG  1 
ATOM   2135 O OD1 . ASP B 2 72  ? 34.05600  16.30369 33.65791  1.000 63.81172  ? 70  ASP L OD1 1 
ATOM   2136 O OD2 . ASP B 2 72  ? 33.40367  16.31781 35.75049  1.000 70.89427  ? 70  ASP L OD2 1 
ATOM   2137 N N   . PHE B 2 73  ? 30.78139  20.17902 33.09614  1.000 59.14041  ? 71  PHE L N   1 
ATOM   2138 C CA  . PHE B 2 73  ? 30.04669  21.42556 32.93093  1.000 54.66820  ? 71  PHE L CA  1 
ATOM   2139 C C   . PHE B 2 73  ? 28.82273  21.42309 33.83273  1.000 55.67913  ? 71  PHE L C   1 
ATOM   2140 O O   . PHE B 2 73  ? 28.35199  20.37487 34.28016  1.000 50.73975  ? 71  PHE L O   1 
ATOM   2141 C CB  . PHE B 2 73  ? 29.63081  21.64231 31.47296  1.000 49.29122  ? 71  PHE L CB  1 
ATOM   2142 C CG  . PHE B 2 73  ? 30.75639  21.48345 30.50517  1.000 57.86990  ? 71  PHE L CG  1 
ATOM   2143 C CD1 . PHE B 2 73  ? 31.62727  22.53481 30.25882  1.000 61.92630  ? 71  PHE L CD1 1 
ATOM   2144 C CD2 . PHE B 2 73  ? 30.96155  20.27716 29.85513  1.000 62.99996  ? 71  PHE L CD2 1 
ATOM   2145 C CE1 . PHE B 2 73  ? 32.67869  22.38948 29.37408  1.000 60.94704  ? 71  PHE L CE1 1 
ATOM   2146 C CE2 . PHE B 2 73  ? 32.01269  20.12135 28.96702  1.000 56.36781  ? 71  PHE L CE2 1 
ATOM   2147 C CZ  . PHE B 2 73  ? 32.87451  21.17846 28.72747  1.000 60.25983  ? 71  PHE L CZ  1 
ATOM   2148 N N   . THR B 2 74  ? 28.30309  22.61965 34.08543  1.000 47.44558  ? 72  THR L N   1 
ATOM   2149 C CA  . THR B 2 74  ? 27.24855  22.80300 35.06952  1.000 47.69166  ? 72  THR L CA  1 
ATOM   2150 C C   . THR B 2 74  ? 26.23994  23.81732 34.55867  1.000 39.87887  ? 72  THR L C   1 
ATOM   2151 O O   . THR B 2 74  ? 26.61974  24.86821 34.03565  1.000 42.18108  ? 72  THR L O   1 
ATOM   2152 C CB  . THR B 2 74  ? 27.83405  23.25848 36.41836  1.000 48.60723  ? 72  THR L CB  1 
ATOM   2153 O OG1 . THR B 2 74  ? 28.44875  22.14110 37.07243  1.000 59.59384  ? 72  THR L OG1 1 
ATOM   2154 C CG2 . THR B 2 74  ? 26.76034  23.83967 37.32075  1.000 49.04851  ? 72  THR L CG2 1 
ATOM   2155 N N   . LEU B 2 75  ? 24.95948  23.47666 34.68252  1.000 47.36720  ? 73  LEU L N   1 
ATOM   2156 C CA  . LEU B 2 75  ? 23.86030  24.41573 34.52145  1.000 32.76336  ? 73  LEU L CA  1 
ATOM   2157 C C   . LEU B 2 75  ? 23.25321  24.64148 35.89531  1.000 29.26430  ? 73  LEU L C   1 
ATOM   2158 O O   . LEU B 2 75  ? 23.02634  23.68179 36.64196  1.000 37.16287  ? 73  LEU L O   1 
ATOM   2159 C CB  . LEU B 2 75  ? 22.80149  23.88963 33.53994  1.000 33.68776  ? 73  LEU L CB  1 
ATOM   2160 C CG  . LEU B 2 75  ? 21.55404  24.75402 33.26768  1.000 30.79012  ? 73  LEU L CG  1 
ATOM   2161 C CD1 . LEU B 2 75  ? 21.91223  26.07319 32.59660  1.000 28.49014  ? 73  LEU L CD1 1 
ATOM   2162 C CD2 . LEU B 2 75  ? 20.51040  24.01535 32.40761  1.000 31.10065  ? 73  LEU L CD2 1 
ATOM   2163 N N   . THR B 2 76  ? 23.01205  25.90240 36.23597  1.000 32.81768  ? 74  THR L N   1 
ATOM   2164 C CA  . THR B 2 76  ? 22.40117  26.26061 37.50775  1.000 40.66013  ? 74  THR L CA  1 
ATOM   2165 C C   . THR B 2 76  ? 21.14284  27.07188 37.23972  1.000 35.59791  ? 74  THR L C   1 
ATOM   2166 O O   . THR B 2 76  ? 21.19229  28.07778 36.52386  1.000 39.15917  ? 74  THR L O   1 
ATOM   2167 C CB  . THR B 2 76  ? 23.37631  27.05051 38.39012  1.000 42.56695  ? 74  THR L CB  1 
ATOM   2168 O OG1 . THR B 2 76  ? 24.53704  26.25314 38.66120  1.000 51.12015  ? 74  THR L OG1 1 
ATOM   2169 C CG2 . THR B 2 76  ? 22.71600  27.42766 39.71955  1.000 43.90455  ? 74  THR L CG2 1 
ATOM   2170 N N   . ILE B 2 77  ? 20.01672  26.62869 37.79463  1.000 31.96614  ? 75  ILE L N   1 
ATOM   2171 C CA  . ILE B 2 77  ? 18.81697  27.45197 37.86909  1.000 28.05189  ? 75  ILE L CA  1 
ATOM   2172 C C   . ILE B 2 77  ? 18.76298  27.98639 39.28890  1.000 37.79472  ? 75  ILE L C   1 
ATOM   2173 O O   . ILE B 2 77  ? 18.61185  27.21391 40.23833  1.000 40.79818  ? 75  ILE L O   1 
ATOM   2174 C CB  . ILE B 2 77  ? 17.54434  26.67202 37.52013  1.000 33.81955  ? 75  ILE L CB  1 
ATOM   2175 C CG1 . ILE B 2 77  ? 17.70921  25.94611 36.18527  1.000 36.05149  ? 75  ILE L CG1 1 
ATOM   2176 C CG2 . ILE B 2 77  ? 16.34915  27.62987 37.48950  1.000 31.00719  ? 75  ILE L CG2 1 
ATOM   2177 C CD1 . ILE B 2 77  ? 16.57239  24.96877 35.85533  1.000 33.83965  ? 75  ILE L CD1 1 
ATOM   2178 N N   . SER B 2 78  ? 18.88457  29.30580 39.44099  1.000 36.14112  ? 76  SER L N   1 
ATOM   2179 C CA  . SER B 2 78  ? 19.13472  29.86367 40.76789  1.000 48.15687  ? 76  SER L CA  1 
ATOM   2180 C C   . SER B 2 78  ? 17.87787  29.86573 41.62984  1.000 54.28393  ? 76  SER L C   1 
ATOM   2181 O O   . SER B 2 78  ? 17.95657  29.66017 42.84887  1.000 59.70114  ? 76  SER L O   1 
ATOM   2182 C CB  . SER B 2 78  ? 19.68801  31.27520 40.64714  1.000 39.37936  ? 76  SER L CB  1 
ATOM   2183 O OG  . SER B 2 78  ? 18.67632  32.14821 40.18647  1.000 46.65938  ? 76  SER L OG  1 
ATOM   2184 N N   . SER B 2 79  ? 16.71233  30.10424 41.02691  1.000 44.01831  ? 77  SER L N   1 
ATOM   2185 C CA  . SER B 2 79  ? 15.44873  30.14485 41.76982  1.000 40.12835  ? 77  SER L CA  1 
ATOM   2186 C C   . SER B 2 79  ? 14.37262  29.47533 40.91161  1.000 39.03393  ? 77  SER L C   1 
ATOM   2187 O O   . SER B 2 79  ? 13.71292  30.13142 40.10308  1.000 40.97071  ? 77  SER L O   1 
ATOM   2188 C CB  . SER B 2 79  ? 15.08473  31.57402 42.12916  1.000 35.15218  ? 77  SER L CB  1 
ATOM   2189 O OG  . SER B 2 79  ? 13.74168  31.66055 42.55700  1.000 40.99370  ? 77  SER L OG  1 
ATOM   2190 N N   . LEU B 2 80  ? 14.18631  28.17328 41.11959  1.000 36.09428  ? 78  LEU L N   1 
ATOM   2191 C CA  . LEU B 2 80  ? 13.30808  27.37742 40.26822  1.000 33.27260  ? 78  LEU L CA  1 
ATOM   2192 C C   . LEU B 2 80  ? 11.89634  27.95166 40.21372  1.000 38.72764  ? 78  LEU L C   1 
ATOM   2193 O O   . LEU B 2 80  ? 11.30306  28.29526 41.24286  1.000 32.82433  ? 78  LEU L O   1 
ATOM   2194 C CB  . LEU B 2 80  ? 13.26392  25.93505 40.77121  1.000 35.26089  ? 78  LEU L CB  1 
ATOM   2195 C CG  . LEU B 2 80  ? 12.61733  24.95881 39.79566  1.000 29.53543  ? 78  LEU L CG  1 
ATOM   2196 C CD1 . LEU B 2 80  ? 13.50087  24.82278 38.58170  1.000 26.52860  ? 78  LEU L CD1 1 
ATOM   2197 C CD2 . LEU B 2 80  ? 12.40504  23.61756 40.46314  1.000 32.16494  ? 78  LEU L CD2 1 
ATOM   2198 N N   . GLN B 2 81  ? 11.35241  28.04121 39.00008  1.000 30.53116  ? 79  GLN L N   1 
ATOM   2199 C CA  . GLN B 2 81  ? 10.00227  28.53502 38.80927  1.000 31.47280  ? 79  GLN L CA  1 
ATOM   2200 C C   . GLN B 2 81  ? 9.13997   27.46336 38.15247  1.000 31.60332  ? 79  GLN L C   1 
ATOM   2201 O O   . GLN B 2 81  ? 9.66807   26.57122 37.47368  1.000 27.24387  ? 79  GLN L O   1 
ATOM   2202 C CB  . GLN B 2 81  ? 10.00462  29.80267 37.94790  1.000 29.44255  ? 79  GLN L CB  1 
ATOM   2203 C CG  . GLN B 2 81  ? 10.73965  30.96732 38.59369  1.000 36.00398  ? 79  GLN L CG  1 
ATOM   2204 C CD  . GLN B 2 81  ? 10.07963  31.43547 39.87723  1.000 37.29304  ? 79  GLN L CD  1 
ATOM   2205 O OE1 . GLN B 2 81  ? 10.67189  31.36831 40.95134  1.000 43.98357  ? 79  GLN L OE1 1 
ATOM   2206 N NE2 . GLN B 2 81  ? 8.84737   31.91541 39.76857  1.000 44.08495  ? 79  GLN L NE2 1 
ATOM   2207 N N   . PRO B 2 82  ? 7.81537   27.51986 38.33675  1.000 26.58848  ? 80  PRO L N   1 
ATOM   2208 C CA  . PRO B 2 82  ? 6.95153   26.50050 37.71780  1.000 24.38417  ? 80  PRO L CA  1 
ATOM   2209 C C   . PRO B 2 82  ? 7.20624   26.33189 36.22779  1.000 28.41053  ? 80  PRO L C   1 
ATOM   2210 O O   . PRO B 2 82  ? 7.28531   25.19618 35.74876  1.000 26.19485  ? 80  PRO L O   1 
ATOM   2211 C CB  . PRO B 2 82  ? 5.53671   27.02898 38.00181  1.000 24.26210  ? 80  PRO L CB  1 
ATOM   2212 C CG  . PRO B 2 82  ? 5.69511   27.84484 39.26444  1.000 26.59853  ? 80  PRO L CG  1 
ATOM   2213 C CD  . PRO B 2 82  ? 7.03806   28.51037 39.10884  1.000 32.67304  ? 80  PRO L CD  1 
ATOM   2214 N N   . GLU B 2 83  ? 7.40187   27.43211 35.49187  1.000 24.37063  ? 81  GLU L N   1 
ATOM   2215 C CA  . GLU B 2 83  ? 7.60465   27.34545 34.05138  1.000 23.42453  ? 81  GLU L CA  1 
ATOM   2216 C C   . GLU B 2 83  ? 8.94659   26.73208 33.67084  1.000 29.10794  ? 81  GLU L C   1 
ATOM   2217 O O   . GLU B 2 83  ? 9.18698   26.51837 32.47821  1.000 27.51740  ? 81  GLU L O   1 
ATOM   2218 C CB  . GLU B 2 83  ? 7.45531   28.73228 33.40677  1.000 31.37473  ? 81  GLU L CB  1 
ATOM   2219 C CG  . GLU B 2 83  ? 8.46190   29.78607 33.86671  1.000 34.21631  ? 81  GLU L CG  1 
ATOM   2220 C CD  . GLU B 2 83  ? 7.96907   30.63250 35.04969  1.000 47.53564  ? 81  GLU L CD  1 
ATOM   2221 O OE1 . GLU B 2 83  ? 7.33244   30.08469 35.98910  1.000 38.76201  ? 81  GLU L OE1 1 
ATOM   2222 O OE2 . GLU B 2 83  ? 8.21772   31.85984 35.03197  1.000 54.13946  ? 81  GLU L OE2 1 
ATOM   2223 N N   . ASP B 2 84  ? 9.81683   26.42792 34.63367  1.000 21.53244  ? 82  ASP L N   1 
ATOM   2224 C CA  . ASP B 2 84  ? 11.06759  25.76177 34.30938  1.000 27.28022  ? 82  ASP L CA  1 
ATOM   2225 C C   . ASP B 2 84  ? 10.90809  24.25695 34.17434  1.000 24.48138  ? 82  ASP L C   1 
ATOM   2226 O O   . ASP B 2 84  ? 11.90057  23.57168 33.91759  1.000 24.71725  ? 82  ASP L O   1 
ATOM   2227 C CB  . ASP B 2 84  ? 12.14277  26.05572 35.36496  1.000 23.60842  ? 82  ASP L CB  1 
ATOM   2228 C CG  . ASP B 2 84  ? 12.44469  27.53416 35.50048  1.000 28.18958  ? 82  ASP L CG  1 
ATOM   2229 O OD1 . ASP B 2 84  ? 12.22460  28.29509 34.52886  1.000 27.82077  ? 82  ASP L OD1 1 
ATOM   2230 O OD2 . ASP B 2 84  ? 12.90088  27.93354 36.59568  1.000 30.01711  ? 82  ASP L OD2 1 
ATOM   2231 N N   . PHE B 2 85  ? 9.70475   23.71785 34.36527  1.000 24.94306  ? 83  PHE L N   1 
ATOM   2232 C CA  . PHE B 2 85  ? 9.50535   22.30164 34.09101  1.000 23.53794  ? 83  PHE L CA  1 
ATOM   2233 C C   . PHE B 2 85  ? 9.89450   22.00794 32.64438  1.000 19.18274  ? 83  PHE L C   1 
ATOM   2234 O O   . PHE B 2 85  ? 9.30498   22.56498 31.71521  1.000 23.88311  ? 83  PHE L O   1 
ATOM   2235 C CB  . PHE B 2 85  ? 8.05792   21.88328 34.32202  1.000 21.41482  ? 83  PHE L CB  1 
ATOM   2236 C CG  . PHE B 2 85  ? 7.74992   20.52048 33.74872  1.000 26.33202  ? 83  PHE L CG  1 
ATOM   2237 C CD1 . PHE B 2 85  ? 8.10513   19.37303 34.43962  1.000 35.05776  ? 83  PHE L CD1 1 
ATOM   2238 C CD2 . PHE B 2 85  ? 7.14806   20.38770 32.50940  1.000 32.47242  ? 83  PHE L CD2 1 
ATOM   2239 C CE1 . PHE B 2 85  ? 7.85288   18.12173 33.92055  1.000 35.72265  ? 83  PHE L CE1 1 
ATOM   2240 C CE2 . PHE B 2 85  ? 6.89003   19.12774 31.98664  1.000 30.68453  ? 83  PHE L CE2 1 
ATOM   2241 C CZ  . PHE B 2 85  ? 7.25190   18.00193 32.69373  1.000 27.56090  ? 83  PHE L CZ  1 
ATOM   2242 N N   . ALA B 2 86  ? 10.86179  21.11890 32.45656  1.000 22.51730  ? 84  ALA L N   1 
ATOM   2243 C CA  . ALA B 2 86  ? 11.37283  20.84811 31.12038  1.000 24.06816  ? 84  ALA L CA  1 
ATOM   2244 C C   . ALA B 2 86  ? 12.40454  19.73803 31.21487  1.000 20.87187  ? 84  ALA L C   1 
ATOM   2245 O O   . ALA B 2 86  ? 12.78757  19.30090 32.30424  1.000 23.76368  ? 84  ALA L O   1 
ATOM   2246 C CB  . ALA B 2 86  ? 12.00885  22.09019 30.48888  1.000 17.66864  ? 84  ALA L CB  1 
ATOM   2247 N N   . THR B 2 87  ? 12.85583  19.29376 30.05033  1.000 19.12106  ? 85  THR L N   1 
ATOM   2248 C CA  . THR B 2 87  ? 14.03978  18.46435 29.94088  1.000 20.65530  ? 85  THR L CA  1 
ATOM   2249 C C   . THR B 2 87  ? 15.18499  19.32460 29.43273  1.000 22.41624  ? 85  THR L C   1 
ATOM   2250 O O   . THR B 2 87  ? 15.04572  20.00423 28.41182  1.000 24.96557  ? 85  THR L O   1 
ATOM   2251 C CB  . THR B 2 87  ? 13.80331  17.27727 29.01035  1.000 25.77987  ? 85  THR L CB  1 
ATOM   2252 O OG1 . THR B 2 87  ? 12.73727  16.48916 29.54835  1.000 23.82845  ? 85  THR L OG1 1 
ATOM   2253 C CG2 . THR B 2 87  ? 15.07068  16.41158 28.92960  1.000 24.44903  ? 85  THR L CG2 1 
ATOM   2254 N N   . TYR B 2 88  ? 16.29963  19.30480 30.15833  1.000 25.06145  ? 86  TYR L N   1 
ATOM   2255 C CA  . TYR B 2 88  ? 17.47015  20.11852 29.85655  1.000 26.07462  ? 86  TYR L CA  1 
ATOM   2256 C C   . TYR B 2 88  ? 18.55238  19.23777 29.25554  1.000 27.11368  ? 86  TYR L C   1 
ATOM   2257 O O   . TYR B 2 88  ? 18.83824  18.15683 29.78288  1.000 28.35942  ? 86  TYR L O   1 
ATOM   2258 C CB  . TYR B 2 88  ? 17.98131  20.82418 31.12288  1.000 24.93346  ? 86  TYR L CB  1 
ATOM   2259 C CG  . TYR B 2 88  ? 16.97140  21.82052 31.65385  1.000 25.29775  ? 86  TYR L CG  1 
ATOM   2260 C CD1 . TYR B 2 88  ? 15.95797  21.42463 32.53008  1.000 25.17915  ? 86  TYR L CD1 1 
ATOM   2261 C CD2 . TYR B 2 88  ? 17.00036  23.14205 31.24902  1.000 22.58426  ? 86  TYR L CD2 1 
ATOM   2262 C CE1 . TYR B 2 88  ? 15.00609  22.32713 32.99031  1.000 24.20906  ? 86  TYR L CE1 1 
ATOM   2263 C CE2 . TYR B 2 88  ? 16.06403  24.05338 31.71511  1.000 24.14150  ? 86  TYR L CE2 1 
ATOM   2264 C CZ  . TYR B 2 88  ? 15.07216  23.63573 32.58426  1.000 18.40418  ? 86  TYR L CZ  1 
ATOM   2265 O OH  . TYR B 2 88  ? 14.14110  24.53545 33.01627  1.000 24.45394  ? 86  TYR L OH  1 
ATOM   2266 N N   . TYR B 2 89  ? 19.14202  19.70121 28.15318  1.000 24.43164  ? 87  TYR L N   1 
ATOM   2267 C CA  . TYR B 2 89  ? 20.19477  18.99583 27.43436  1.000 23.76569  ? 87  TYR L CA  1 
ATOM   2268 C C   . TYR B 2 89  ? 21.42830  19.88223 27.35023  1.000 30.36798  ? 87  TYR L C   1 
ATOM   2269 O O   . TYR B 2 89  ? 21.32711  21.05841 26.97986  1.000 33.31995  ? 87  TYR L O   1 
ATOM   2270 C CB  . TYR B 2 89  ? 19.77123  18.63530 25.99923  1.000 22.90107  ? 87  TYR L CB  1 
ATOM   2271 C CG  . TYR B 2 89  ? 18.56762  17.71054 25.89274  1.000 28.33228  ? 87  TYR L CG  1 
ATOM   2272 C CD1 . TYR B 2 89  ? 17.28263  18.21889 25.85093  1.000 24.63738  ? 87  TYR L CD1 1 
ATOM   2273 C CD2 . TYR B 2 89  ? 18.73051  16.33496 25.83337  1.000 25.17317  ? 87  TYR L CD2 1 
ATOM   2274 C CE1 . TYR B 2 89  ? 16.18143  17.38234 25.76052  1.000 27.16116  ? 87  TYR L CE1 1 
ATOM   2275 C CE2 . TYR B 2 89  ? 17.63232  15.48324 25.74448  1.000 26.08344  ? 87  TYR L CE2 1 
ATOM   2276 C CZ  . TYR B 2 89  ? 16.36599  16.01832 25.70384  1.000 27.54959  ? 87  TYR L CZ  1 
ATOM   2277 O OH  . TYR B 2 89  ? 15.27185  15.19333 25.61608  1.000 31.61509  ? 87  TYR L OH  1 
ATOM   2278 N N   . CYS B 2 90  ? 22.58827  19.31618 27.64731  1.000 26.66671  ? 88  CYS L N   1 
ATOM   2279 C CA  . CYS B 2 90  ? 23.82694  19.94005 27.21048  1.000 35.37942  ? 88  CYS L CA  1 
ATOM   2280 C C   . CYS B 2 90  ? 24.15790  19.44541 25.81431  1.000 33.83317  ? 88  CYS L C   1 
ATOM   2281 O O   . CYS B 2 90  ? 23.81932  18.32093 25.43392  1.000 33.84750  ? 88  CYS L O   1 
ATOM   2282 C CB  . CYS B 2 90  ? 24.99582  19.63568 28.15315  1.000 41.06461  ? 88  CYS L CB  1 
ATOM   2283 S SG  . CYS B 2 90  ? 25.28854  17.87647 28.43298  1.000 50.80762  ? 88  CYS L SG  1 
ATOM   2284 N N   . VAL B 2 91  ? 24.79813  20.30504 25.04158  1.000 26.78706  ? 89  VAL L N   1 
ATOM   2285 C CA  . VAL B 2 91  ? 25.29585  19.93567 23.72773  1.000 31.77976  ? 89  VAL L CA  1 
ATOM   2286 C C   . VAL B 2 91  ? 26.73496  20.41425 23.62805  1.000 40.51754  ? 89  VAL L C   1 
ATOM   2287 O O   . VAL B 2 91  ? 27.06488  21.52015 24.07178  1.000 37.49220  ? 89  VAL L O   1 
ATOM   2288 C CB  . VAL B 2 91  ? 24.42580  20.51094 22.58845  1.000 28.21421  ? 89  VAL L CB  1 
ATOM   2289 C CG1 . VAL B 2 91  ? 24.42540  22.03367 22.58793  1.000 33.36203  ? 89  VAL L CG1 1 
ATOM   2290 C CG2 . VAL B 2 91  ? 24.89496  19.97373 21.25363  1.000 36.36059  ? 89  VAL L CG2 1 
ATOM   2291 N N   . GLY B 2 92  ? 27.59710  19.56490 23.08311  1.000 41.98568  ? 90  GLY L N   1 
ATOM   2292 C CA  . GLY B 2 92  ? 29.01075  19.86502 22.97672  1.000 49.80356  ? 90  GLY L CA  1 
ATOM   2293 C C   . GLY B 2 92  ? 29.48436  19.76501 21.54095  1.000 48.55615  ? 90  GLY L C   1 
ATOM   2294 O O   . GLY B 2 92  ? 29.00724  18.93128 20.76978  1.000 43.97707  ? 90  GLY L O   1 
ATOM   2295 N N   . HIS B 2 93  ? 30.42150  20.63750 21.18345  1.000 47.00517  ? 91  HIS L N   1 
ATOM   2296 C CA  . HIS B 2 93  ? 31.08369  20.59224 19.89048  1.000 42.34332  ? 91  HIS L CA  1 
ATOM   2297 C C   . HIS B 2 93  ? 32.48268  20.00699 20.05957  1.000 49.08254  ? 91  HIS L C   1 
ATOM   2298 O O   . HIS B 2 93  ? 33.16165  20.27415 21.05742  1.000 47.66850  ? 91  HIS L O   1 
ATOM   2299 C CB  . HIS B 2 93  ? 31.15276  21.98778 19.27791  1.000 47.62810  ? 91  HIS L CB  1 
ATOM   2300 C CG  . HIS B 2 93  ? 31.51662  21.99642 17.83015  1.000 49.59222  ? 91  HIS L CG  1 
ATOM   2301 N ND1 . HIS B 2 93  ? 30.83037  21.26414 16.88759  1.000 50.38779  ? 91  HIS L ND1 1 
ATOM   2302 C CD2 . HIS B 2 93  ? 32.49124  22.65505 17.15969  1.000 53.67868  ? 91  HIS L CD2 1 
ATOM   2303 C CE1 . HIS B 2 93  ? 31.36402  21.47136 15.69723  1.000 51.08233  ? 91  HIS L CE1 1 
ATOM   2304 N NE2 . HIS B 2 93  ? 32.37654  22.30865 15.83521  1.000 52.56036  ? 91  HIS L NE2 1 
ATOM   2305 N N   . TYR B 2 94  ? 32.89744  19.18664 19.09343  1.000 47.24146  ? 92  TYR L N   1 
ATOM   2306 C CA  . TYR B 2 94  ? 34.15679  18.45876 19.16658  1.000 44.69625  ? 92  TYR L CA  1 
ATOM   2307 C C   . TYR B 2 94  ? 34.81073  18.43229 17.79702  1.000 52.53690  ? 92  TYR L C   1 
ATOM   2308 O O   . TYR B 2 94  ? 34.16406  18.68051 16.77804  1.000 48.48799  ? 92  TYR L O   1 
ATOM   2309 C CB  . TYR B 2 94  ? 33.96598  17.01179 19.62792  1.000 47.30685  ? 92  TYR L CB  1 
ATOM   2310 C CG  . TYR B 2 94  ? 33.23916  16.85349 20.93092  1.000 53.43509  ? 92  TYR L CG  1 
ATOM   2311 C CD1 . TYR B 2 94  ? 31.85479  16.95030 20.99107  1.000 55.46995  ? 92  TYR L CD1 1 
ATOM   2312 C CD2 . TYR B 2 94  ? 33.93078  16.57905 22.10010  1.000 54.09868  ? 92  TYR L CD2 1 
ATOM   2313 C CE1 . TYR B 2 94  ? 31.18394  16.80089 22.18297  1.000 48.65511  ? 92  TYR L CE1 1 
ATOM   2314 C CE2 . TYR B 2 94  ? 33.26830  16.42527 23.29530  1.000 56.20027  ? 92  TYR L CE2 1 
ATOM   2315 C CZ  . TYR B 2 94  ? 31.89458  16.53722 23.32753  1.000 58.36498  ? 92  TYR L CZ  1 
ATOM   2316 O OH  . TYR B 2 94  ? 31.22489  16.38120 24.51066  1.000 61.13870  ? 92  TYR L OH  1 
ATOM   2317 N N   . GLY B 2 95  ? 36.10924  18.10781 17.78387  1.000 56.11356  ? 93  GLY L N   1 
ATOM   2318 C CA  . GLY B 2 95  ? 36.81712  17.78599 16.56295  1.000 64.28821  ? 93  GLY L CA  1 
ATOM   2319 C C   . GLY B 2 95  ? 38.16333  18.47765 16.47256  1.000 68.78537  ? 93  GLY L C   1 
ATOM   2320 O O   . GLY B 2 95  ? 38.67409  19.04849 17.44418  1.000 66.08102  ? 93  GLY L O   1 
ATOM   2321 N N   . SER B 2 96  ? 38.74979  18.41083 15.27625  1.000 68.87470  ? 94  SER L N   1 
ATOM   2322 C CA  . SER B 2 96  ? 40.01190  19.07144 14.96853  1.000 67.23592  ? 94  SER L CA  1 
ATOM   2323 C C   . SER B 2 96  ? 39.80550  20.01784 13.79553  1.000 68.73940  ? 94  SER L C   1 
ATOM   2324 O O   . SER B 2 96  ? 38.66473  20.33968 13.44778  1.000 61.26476  ? 94  SER L O   1 
ATOM   2325 C CB  . SER B 2 96  ? 41.10206  18.04944 14.63081  1.000 64.74207  ? 94  SER L CB  1 
ATOM   2326 O OG  . SER B 2 96  ? 40.88130  16.80920 15.28216  1.000 68.99926  ? 94  SER L OG  1 
ATOM   2327 N N   . GLU B 2 97  ? 40.89899  20.46173 13.16986  1.000 71.04103  ? 95  GLU L N   1 
ATOM   2328 C CA  . GLU B 2 97  ? 40.77318  21.20962 11.92573  1.000 68.81789  ? 95  GLU L CA  1 
ATOM   2329 C C   . GLU B 2 97  ? 40.23432  20.33841 10.80137  1.000 61.56726  ? 95  GLU L C   1 
ATOM   2330 O O   . GLU B 2 97  ? 39.78569  20.87283 9.78018   1.000 58.49285  ? 95  GLU L O   1 
ATOM   2331 C CB  . GLU B 2 97  ? 42.12337  21.80559 11.52157  1.000 72.00635  ? 95  GLU L CB  1 
ATOM   2332 C CG  . GLU B 2 97  ? 42.99928  22.21010 12.69167  1.000 71.66601  ? 95  GLU L CG  1 
ATOM   2333 C CD  . GLU B 2 97  ? 43.88627  21.07289 13.17830  1.000 85.85789  ? 95  GLU L CD  1 
ATOM   2334 O OE1 . GLU B 2 97  ? 44.81933  20.68276 12.44081  1.000 85.19819  ? 95  GLU L OE1 1 
ATOM   2335 O OE2 . GLU B 2 97  ? 43.64324  20.56223 14.29400  1.000 82.41529  ? 95  GLU L OE2 1 
ATOM   2336 N N   . ASN B 2 98  A 40.26524  19.01285 10.97833  1.000 62.35943  ? 95  ASN L N   1 
ATOM   2337 C CA  . ASN B 2 98  A 39.80350  18.04867 9.98438   1.000 75.18293  ? 95  ASN L CA  1 
ATOM   2338 C C   . ASN B 2 98  A 38.65437  17.18684 10.49162  1.000 74.70404  ? 95  ASN L C   1 
ATOM   2339 O O   . ASN B 2 98  A 38.29509  16.20495 9.83139   1.000 74.66345  ? 95  ASN L O   1 
ATOM   2340 C CB  . ASN B 2 98  A 40.95725  17.14068 9.54899   1.000 76.27652  ? 95  ASN L CB  1 
ATOM   2341 C CG  . ASN B 2 98  A 42.23708  17.90495 9.31666   1.000 77.56851  ? 95  ASN L CG  1 
ATOM   2342 O OD1 . ASN B 2 98  A 43.20618  17.76471 10.06986  1.000 74.23733  ? 95  ASN L OD1 1 
ATOM   2343 N ND2 . ASN B 2 98  A 42.24855  18.72990 8.27307   1.000 64.81341  ? 95  ASN L ND2 1 
ATOM   2344 N N   . ASP B 2 99  B 38.08147  17.51641 11.64867  1.000 70.34889  ? 95  ASP L N   1 
ATOM   2345 C CA  . ASP B 2 99  B 37.01577  16.73770 12.26448  1.000 71.18553  ? 95  ASP L CA  1 
ATOM   2346 C C   . ASP B 2 99  B 36.01054  17.67841 12.90767  1.000 66.44934  ? 95  ASP L C   1 
ATOM   2347 O O   . ASP B 2 99  B 36.39948  18.67111 13.52775  1.000 63.37948  ? 95  ASP L O   1 
ATOM   2348 C CB  . ASP B 2 99  B 37.56395  15.77538 13.32794  1.000 68.72623  ? 95  ASP L CB  1 
ATOM   2349 C CG  . ASP B 2 99  B 38.08773  14.49070 12.73417  1.000 72.26443  ? 95  ASP L CG  1 
ATOM   2350 O OD1 . ASP B 2 99  B 37.38107  13.89364 11.89391  1.000 78.79483  ? 95  ASP L OD1 1 
ATOM   2351 O OD2 . ASP B 2 99  B 39.20687  14.08135 13.10307  1.000 75.99348  ? 95  ASP L OD2 1 
ATOM   2352 N N   . ALA B 2 100 C 34.72201  17.35349 12.76956  1.000 69.41886  ? 95  ALA L N   1 
ATOM   2353 C CA  . ALA B 2 100 C 33.64008  18.14827 13.34881  1.000 61.39934  ? 95  ALA L CA  1 
ATOM   2354 C C   . ALA B 2 100 C 32.55362  17.20979 13.85017  1.000 58.87733  ? 95  ALA L C   1 
ATOM   2355 O O   . ALA B 2 100 C 31.99669  16.43263 13.07050  1.000 58.97844  ? 95  ALA L O   1 
ATOM   2356 C CB  . ALA B 2 100 C 33.06437  19.13609 12.32778  1.000 58.82635  ? 95  ALA L CB  1 
ATOM   2357 N N   . TYR B 2 101 D 32.24811  17.28428 15.14389  1.000 49.34385  ? 95  TYR L N   1 
ATOM   2358 C CA  . TYR B 2 101 D 31.25223  16.41569 15.75343  1.000 45.04544  ? 95  TYR L CA  1 
ATOM   2359 C C   . TYR B 2 101 D 30.47007  17.18053 16.81119  1.000 47.45568  ? 95  TYR L C   1 
ATOM   2360 O O   . TYR B 2 101 D 30.97979  18.11785 17.43214  1.000 47.03223  ? 95  TYR L O   1 
ATOM   2361 C CB  . TYR B 2 101 D 31.89498  15.17577 16.39043  1.000 50.08686  ? 95  TYR L CB  1 
ATOM   2362 C CG  . TYR B 2 101 D 32.74662  14.37844 15.43585  1.000 65.98074  ? 95  TYR L CG  1 
ATOM   2363 C CD1 . TYR B 2 101 D 32.16453  13.58665 14.45224  1.000 66.52508  ? 95  TYR L CD1 1 
ATOM   2364 C CD2 . TYR B 2 101 D 34.13363  14.41855 15.51115  1.000 65.61769  ? 95  TYR L CD2 1 
ATOM   2365 C CE1 . TYR B 2 101 D 32.93963  12.85774 13.56685  1.000 63.76244  ? 95  TYR L CE1 1 
ATOM   2366 C CE2 . TYR B 2 101 D 34.91789  13.68924 14.63071  1.000 64.27993  ? 95  TYR L CE2 1 
ATOM   2367 C CZ  . TYR B 2 101 D 34.31347  12.91141 13.66091  1.000 68.33989  ? 95  TYR L CZ  1 
ATOM   2368 O OH  . TYR B 2 101 D 35.08231  12.18427 12.77981  1.000 73.80422  ? 95  TYR L OH  1 
ATOM   2369 N N   . TYR B 2 102 ? 29.21923  16.76573 17.00441  1.000 50.16394  ? 96  TYR L N   1 
ATOM   2370 C CA  . TYR B 2 102 ? 28.35937  17.26451 18.06744  1.000 38.41090  ? 96  TYR L CA  1 
ATOM   2371 C C   . TYR B 2 102 ? 27.77929  16.09104 18.83414  1.000 39.01405  ? 96  TYR L C   1 
ATOM   2372 O O   . TYR B 2 102 ? 27.44412  15.05938 18.24866  1.000 40.28080  ? 96  TYR L O   1 
ATOM   2373 C CB  . TYR B 2 102 ? 27.19843  18.06925 17.54107  1.000 37.25628  ? 96  TYR L CB  1 
ATOM   2374 C CG  . TYR B 2 102 ? 27.49356  19.46503 17.10780  1.000 37.50866  ? 96  TYR L CG  1 
ATOM   2375 C CD1 . TYR B 2 102 ? 27.49219  20.51054 18.02163  1.000 41.10690  ? 96  TYR L CD1 1 
ATOM   2376 C CD2 . TYR B 2 102 ? 27.71565  19.75518 15.77700  1.000 38.25699  ? 96  TYR L CD2 1 
ATOM   2377 C CE1 . TYR B 2 102 ? 27.72481  21.80616 17.61349  1.000 37.10427  ? 96  TYR L CE1 1 
ATOM   2378 C CE2 . TYR B 2 102 ? 27.95763  21.03699 15.36383  1.000 42.11233  ? 96  TYR L CE2 1 
ATOM   2379 C CZ  . TYR B 2 102 ? 27.96084  22.06036 16.27935  1.000 43.28860  ? 96  TYR L CZ  1 
ATOM   2380 O OH  . TYR B 2 102 ? 28.19733  23.34593 15.84359  1.000 37.24187  ? 96  TYR L OH  1 
ATOM   2381 N N   . ALA B 2 103 ? 27.62456  16.26637 20.14099  1.000 38.46785  ? 97  ALA L N   1 
ATOM   2382 C CA  . ALA B 2 103 ? 26.99901  15.24328 20.96437  1.000 39.35529  ? 97  ALA L CA  1 
ATOM   2383 C C   . ALA B 2 103 ? 26.05481  15.89097 21.96285  1.000 44.25037  ? 97  ALA L C   1 
ATOM   2384 O O   . ALA B 2 103 ? 26.31525  16.99390 22.45328  1.000 46.50236  ? 97  ALA L O   1 
ATOM   2385 C CB  . ALA B 2 103 ? 28.03980  14.40048 21.70245  1.000 42.17686  ? 97  ALA L CB  1 
ATOM   2386 N N   . PHE B 2 104 ? 24.95720  15.19629 22.25251  1.000 40.82883  ? 98  PHE L N   1 
ATOM   2387 C CA  . PHE B 2 104 ? 23.98039  15.60810 23.24696  1.000 31.37581  ? 98  PHE L CA  1 
ATOM   2388 C C   . PHE B 2 104 ? 24.07104  14.68381 24.45616  1.000 40.51484  ? 98  PHE L C   1 
ATOM   2389 O O   . PHE B 2 104 ? 24.24796  13.47139 24.30825  1.000 41.25475  ? 98  PHE L O   1 
ATOM   2390 C CB  . PHE B 2 104 ? 22.55313  15.55265 22.68212  1.000 32.03305  ? 98  PHE L CB  1 
ATOM   2391 C CG  . PHE B 2 104 ? 22.26995  16.54655 21.58429  1.000 31.89573  ? 98  PHE L CG  1 
ATOM   2392 C CD1 . PHE B 2 104 ? 21.83957  17.82928 21.87998  1.000 32.44303  ? 98  PHE L CD1 1 
ATOM   2393 C CD2 . PHE B 2 104 ? 22.39516  16.18753 20.25562  1.000 34.21673  ? 98  PHE L CD2 1 
ATOM   2394 C CE1 . PHE B 2 104 ? 21.55963  18.74045 20.86729  1.000 25.63945  ? 98  PHE L CE1 1 
ATOM   2395 C CE2 . PHE B 2 104 ? 22.11883  17.09529 19.24631  1.000 29.98185  ? 98  PHE L CE2 1 
ATOM   2396 C CZ  . PHE B 2 104 ? 21.70058  18.36788 19.55580  1.000 34.81227  ? 98  PHE L CZ  1 
ATOM   2397 N N   . GLY B 2 105 ? 23.94361  15.25232 25.65182  1.000 36.79203  ? 99  GLY L N   1 
ATOM   2398 C CA  . GLY B 2 105 ? 23.65061  14.44482 26.81406  1.000 37.50360  ? 99  GLY L CA  1 
ATOM   2399 C C   . GLY B 2 105 ? 22.27206  13.81381 26.70446  1.000 35.92479  ? 99  GLY L C   1 
ATOM   2400 O O   . GLY B 2 105 ? 21.45954  14.15371 25.84505  1.000 29.69818  ? 99  GLY L O   1 
ATOM   2401 N N   . GLN B 2 106 ? 21.99550  12.87161 27.60211  1.000 32.26886  ? 100 GLN L N   1 
ATOM   2402 C CA  . GLN B 2 106 ? 20.74082  12.13882 27.49868  1.000 35.51908  ? 100 GLN L CA  1 
ATOM   2403 C C   . GLN B 2 106 ? 19.54673  12.92829 28.02119  1.000 30.49536  ? 100 GLN L C   1 
ATOM   2404 O O   . GLN B 2 106 ? 18.40888  12.47668 27.86610  1.000 31.17360  ? 100 GLN L O   1 
ATOM   2405 C CB  . GLN B 2 106 ? 20.85019  10.79740 28.22919  1.000 28.73804  ? 100 GLN L CB  1 
ATOM   2406 C CG  . GLN B 2 106 ? 20.52969  10.84104 29.71336  1.000 36.37792  ? 100 GLN L CG  1 
ATOM   2407 C CD  . GLN B 2 106 ? 21.72640  11.20731 30.59061  1.000 44.38795  ? 100 GLN L CD  1 
ATOM   2408 O OE1 . GLN B 2 106 ? 22.71858  11.78719 30.12650  1.000 38.78185  ? 100 GLN L OE1 1 
ATOM   2409 N NE2 . GLN B 2 106 ? 21.63039  10.86528 31.87078  1.000 40.85966  ? 100 GLN L NE2 1 
ATOM   2410 N N   . GLY B 2 107 ? 19.76878  14.09749 28.60739  1.000 27.78570  ? 101 GLY L N   1 
ATOM   2411 C CA  . GLY B 2 107 ? 18.67656  14.89952 29.10569  1.000 26.13551  ? 101 GLY L CA  1 
ATOM   2412 C C   . GLY B 2 107 ? 18.42325  14.70806 30.58494  1.000 34.06349  ? 101 GLY L C   1 
ATOM   2413 O O   . GLY B 2 107 ? 18.58275  13.60698 31.11720  1.000 35.34361  ? 101 GLY L O   1 
ATOM   2414 N N   . THR B 2 108 ? 18.05616  15.79081 31.26406  1.000 28.09957  ? 102 THR L N   1 
ATOM   2415 C CA  . THR B 2 108 ? 17.67373  15.76382 32.66604  1.000 28.12524  ? 102 THR L CA  1 
ATOM   2416 C C   . THR B 2 108 ? 16.28613  16.37192 32.78137  1.000 26.87596  ? 102 THR L C   1 
ATOM   2417 O O   . THR B 2 108 ? 16.09791  17.55159 32.47143  1.000 26.25692  ? 102 THR L O   1 
ATOM   2418 C CB  . THR B 2 108 ? 18.66584  16.54641 33.53555  1.000 29.65029  ? 102 THR L CB  1 
ATOM   2419 O OG1 . THR B 2 108 ? 19.98401  16.01846 33.36327  1.000 33.04824  ? 102 THR L OG1 1 
ATOM   2420 C CG2 . THR B 2 108 ? 18.26673  16.46528 34.99878  1.000 31.60588  ? 102 THR L CG2 1 
ATOM   2421 N N   . LYS B 2 109 ? 15.32095  15.57207 33.21551  1.000 27.42985  ? 103 LYS L N   1 
ATOM   2422 C CA  . LYS B 2 109 ? 13.96984  16.06626 33.39878  1.000 25.04708  ? 103 LYS L CA  1 
ATOM   2423 C C   . LYS B 2 109 ? 13.88126  16.73391 34.76050  1.000 27.69453  ? 103 LYS L C   1 
ATOM   2424 O O   . LYS B 2 109 ? 14.28855  16.15491 35.76687  1.000 31.20012  ? 103 LYS L O   1 
ATOM   2425 C CB  . LYS B 2 109 ? 12.96536  14.92176 33.28082  1.000 28.43784  ? 103 LYS L CB  1 
ATOM   2426 C CG  . LYS B 2 109 ? 11.54248  15.36345 33.00594  1.000 37.57951  ? 103 LYS L CG  1 
ATOM   2427 C CD  . LYS B 2 109 ? 10.65628  14.14266 32.74291  1.000 43.46390  ? 103 LYS L CD  1 
ATOM   2428 C CE  . LYS B 2 109 ? 9.33653   14.52143 32.06923  1.000 53.43125  ? 103 LYS L CE  1 
ATOM   2429 N NZ  . LYS B 2 109 ? 8.35436   13.38905 32.04196  1.000 57.77996  ? 103 LYS L NZ  1 
ATOM   2430 N N   . VAL B 2 110 ? 13.40175  17.97017 34.78858  1.000 27.37529  ? 104 VAL L N   1 
ATOM   2431 C CA  . VAL B 2 110 ? 13.24821  18.71334 36.02783  1.000 28.32416  ? 104 VAL L CA  1 
ATOM   2432 C C   . VAL B 2 110 ? 11.76235  18.78970 36.33287  1.000 36.86095  ? 104 VAL L C   1 
ATOM   2433 O O   . VAL B 2 110 ? 11.00055  19.39052 35.56806  1.000 33.30960  ? 104 VAL L O   1 
ATOM   2434 C CB  . VAL B 2 110 ? 13.86901  20.11428 35.93506  1.000 28.31057  ? 104 VAL L CB  1 
ATOM   2435 C CG1 . VAL B 2 110 ? 13.51926  20.91944 37.16068  1.000 28.05426  ? 104 VAL L CG1 1 
ATOM   2436 C CG2 . VAL B 2 110 ? 15.38836  20.01641 35.78182  1.000 35.05432  ? 104 VAL L CG2 1 
ATOM   2437 N N   . GLU B 2 111 ? 11.35066  18.18820 37.44914  1.000 33.44633  ? 105 GLU L N   1 
ATOM   2438 C CA  . GLU B 2 111 ? 9.96103   18.19405 37.88265  1.000 32.34033  ? 105 GLU L CA  1 
ATOM   2439 C C   . GLU B 2 111 ? 9.79860   19.12636 39.07376  1.000 33.64663  ? 105 GLU L C   1 
ATOM   2440 O O   . GLU B 2 111 ? 10.72607  19.32598 39.86055  1.000 29.28245  ? 105 GLU L O   1 
ATOM   2441 C CB  . GLU B 2 111 ? 9.48785   16.78747 38.26023  1.000 41.96215  ? 105 GLU L CB  1 
ATOM   2442 C CG  . GLU B 2 111 ? 9.70405   15.74285 37.16412  1.000 52.78466  ? 105 GLU L CG  1 
ATOM   2443 C CD  . GLU B 2 111 ? 10.65477  14.62669 37.58972  1.000 51.82359  ? 105 GLU L CD  1 
ATOM   2444 O OE1 . GLU B 2 111 ? 10.52200  14.11465 38.72563  1.000 53.52218  ? 105 GLU L OE1 1 
ATOM   2445 O OE2 . GLU B 2 111 ? 11.54209  14.26223 36.78844  1.000 48.97159  ? 105 GLU L OE2 1 
ATOM   2446 N N   . ILE B 2 112 ? 8.61574   19.70466 39.19556  1.000 28.10859  ? 106 ILE L N   1 
ATOM   2447 C CA  . ILE B 2 112 ? 8.32830   20.67120 40.24437  1.000 30.13707  ? 106 ILE L CA  1 
ATOM   2448 C C   . ILE B 2 112 ? 7.53383   19.98119 41.34313  1.000 37.64294  ? 106 ILE L C   1 
ATOM   2449 O O   . ILE B 2 112 ? 6.39725   19.54369 41.11740  1.000 28.50338  ? 106 ILE L O   1 
ATOM   2450 C CB  . ILE B 2 112 ? 7.55071   21.87636 39.70766  1.000 29.97902  ? 106 ILE L CB  1 
ATOM   2451 C CG1 . ILE B 2 112 ? 8.19536   22.41998 38.42878  1.000 34.86186  ? 106 ILE L CG1 1 
ATOM   2452 C CG2 . ILE B 2 112 ? 7.43912   22.92875 40.79769  1.000 34.14219  ? 106 ILE L CG2 1 
ATOM   2453 C CD1 . ILE B 2 112 ? 9.66453   22.67784 38.53627  1.000 37.48295  ? 106 ILE L CD1 1 
ATOM   2454 N N   . LYS B 2 113 ? 8.12665   19.89734 42.53225  1.000 34.23659  ? 107 LYS L N   1 
ATOM   2455 C CA  . LYS B 2 113 ? 7.41011   19.44218 43.71590  1.000 28.22233  ? 107 LYS L CA  1 
ATOM   2456 C C   . LYS B 2 113 ? 6.50206   20.56019 44.21743  1.000 32.74059  ? 107 LYS L C   1 
ATOM   2457 O O   . LYS B 2 113 ? 6.94758   21.69678 44.39864  1.000 41.10253  ? 107 LYS L O   1 
ATOM   2458 C CB  . LYS B 2 113 ? 8.40126   19.02431 44.79901  1.000 31.74611  ? 107 LYS L CB  1 
ATOM   2459 C CG  . LYS B 2 113 ? 7.74476   18.67773 46.11512  1.000 43.99922  ? 107 LYS L CG  1 
ATOM   2460 C CD  . LYS B 2 113 ? 8.50354   19.26624 47.30226  1.000 51.06135  ? 107 LYS L CD  1 
ATOM   2461 C CE  . LYS B 2 113 ? 7.57085   19.50293 48.48637  1.000 48.96345  ? 107 LYS L CE  1 
ATOM   2462 N NZ  . LYS B 2 113 ? 6.59366   20.61128 48.22540  1.000 42.45862  ? 107 LYS L NZ  1 
ATOM   2463 N N   . ARG B 2 114 ? 5.21961   20.24834 44.40633  1.000 32.78571  ? 108 ARG L N   1 
ATOM   2464 C CA  . ARG B 2 114 ? 4.24710   21.20351 44.92029  1.000 25.27837  ? 108 ARG L CA  1 
ATOM   2465 C C   . ARG B 2 114 ? 3.36773   20.49378 45.94924  1.000 32.91645  ? 108 ARG L C   1 
ATOM   2466 O O   . ARG B 2 114 ? 3.55182   19.30685 46.23556  1.000 32.37578  ? 108 ARG L O   1 
ATOM   2467 C CB  . ARG B 2 114 ? 3.41533   21.80762 43.78896  1.000 30.68039  ? 108 ARG L CB  1 
ATOM   2468 C CG  . ARG B 2 114 ? 2.69374   20.75262 42.94184  1.000 31.36370  ? 108 ARG L CG  1 
ATOM   2469 C CD  . ARG B 2 114 ? 1.39789   21.29890 42.42611  1.000 29.16874  ? 108 ARG L CD  1 
ATOM   2470 N NE  . ARG B 2 114 ? 0.46400   21.54792 43.51716  1.000 30.62729  ? 108 ARG L NE  1 
ATOM   2471 C CZ  . ARG B 2 114 ? -0.51530  22.43981 43.47902  1.000 26.64089  ? 108 ARG L CZ  1 
ATOM   2472 N NH1 . ARG B 2 114 ? -0.69678  23.22126 42.43147  1.000 31.08135  ? 108 ARG L NH1 1 
ATOM   2473 N NH2 . ARG B 2 114 ? -1.32911  22.55674 44.52588  1.000 30.36344  ? 108 ARG L NH2 1 
ATOM   2474 N N   . THR B 2 115 ? 2.40449   21.22588 46.50450  1.000 30.37898  ? 109 THR L N   1 
ATOM   2475 C CA  . THR B 2 115 ? 1.51018   20.66325 47.50569  1.000 36.47179  ? 109 THR L CA  1 
ATOM   2476 C C   . THR B 2 115 ? 0.45795   19.75568 46.86391  1.000 40.41404  ? 109 THR L C   1 
ATOM   2477 O O   . THR B 2 115 ? 0.08920   19.92009 45.69593  1.000 36.07627  ? 109 THR L O   1 
ATOM   2478 C CB  . THR B 2 115 ? 0.82452   21.78079 48.29087  1.000 36.79458  ? 109 THR L CB  1 
ATOM   2479 O OG1 . THR B 2 115 ? 0.00285   22.54606 47.41027  1.000 48.58280  ? 109 THR L OG1 1 
ATOM   2480 C CG2 . THR B 2 115 ? 1.85505   22.71160 48.91656  1.000 31.06669  ? 109 THR L CG2 1 
ATOM   2481 N N   . VAL B 2 116 ? -0.02386  18.78830 47.65185  1.000 36.19950  ? 110 VAL L N   1 
ATOM   2482 C CA  . VAL B 2 116 ? -1.03025  17.84503 47.18189  1.000 26.76739  ? 110 VAL L CA  1 
ATOM   2483 C C   . VAL B 2 116 ? -2.27275  18.58794 46.71275  1.000 31.77541  ? 110 VAL L C   1 
ATOM   2484 O O   . VAL B 2 116 ? -2.70451  19.56737 47.33381  1.000 33.48498  ? 110 VAL L O   1 
ATOM   2485 C CB  . VAL B 2 116 ? -1.36420  16.84726 48.30311  1.000 35.51331  ? 110 VAL L CB  1 
ATOM   2486 C CG1 . VAL B 2 116 ? -2.65853  16.10150 48.00198  1.000 32.34588  ? 110 VAL L CG1 1 
ATOM   2487 C CG2 . VAL B 2 116 ? -0.21215  15.87357 48.50376  1.000 40.18634  ? 110 VAL L CG2 1 
ATOM   2488 N N   . ALA B 2 117 ? -2.85268  18.13294 45.59377  1.000 26.00219  ? 111 ALA L N   1 
ATOM   2489 C CA  . ALA B 2 117 ? -4.09502  18.70781 45.07955  1.000 21.79307  ? 111 ALA L CA  1 
ATOM   2490 C C   . ALA B 2 117 ? -4.98862  17.58374 44.57569  1.000 24.21870  ? 111 ALA L C   1 
ATOM   2491 O O   . ALA B 2 117 ? -4.57388  16.79105 43.72635  1.000 24.46629  ? 111 ALA L O   1 
ATOM   2492 C CB  . ALA B 2 117 ? -3.82161  19.72147 43.95926  1.000 25.32345  ? 111 ALA L CB  1 
ATOM   2493 N N   . ALA B 2 118 ? -6.20275  17.49832 45.10861  1.000 23.10347  ? 112 ALA L N   1 
ATOM   2494 C CA  . ALA B 2 118 ? -7.11773  16.45702 44.68437  1.000 26.17030  ? 112 ALA L CA  1 
ATOM   2495 C C   . ALA B 2 118 ? -7.69399  16.80842 43.31196  1.000 21.18062  ? 112 ALA L C   1 
ATOM   2496 O O   . ALA B 2 118 ? -7.94163  17.97988 43.01154  1.000 22.34656  ? 112 ALA L O   1 
ATOM   2497 C CB  . ALA B 2 118 ? -8.24585  16.27846 45.69986  1.000 29.22262  ? 112 ALA L CB  1 
ATOM   2498 N N   . PRO B 2 119 ? -7.92063  15.81666 42.45975  1.000 20.87971  ? 113 PRO L N   1 
ATOM   2499 C CA  . PRO B 2 119 ? -8.46504  16.11720 41.13516  1.000 19.43666  ? 113 PRO L CA  1 
ATOM   2500 C C   . PRO B 2 119 ? -9.94109  16.44747 41.20834  1.000 22.02802  ? 113 PRO L C   1 
ATOM   2501 O O   . PRO B 2 119 ? -10.67385 15.94912 42.06433  1.000 21.01974  ? 113 PRO L O   1 
ATOM   2502 C CB  . PRO B 2 119 ? -8.23206  14.81930 40.35471  1.000 21.70316  ? 113 PRO L CB  1 
ATOM   2503 C CG  . PRO B 2 119 ? -8.28379  13.76323 41.39070  1.000 19.59437  ? 113 PRO L CG  1 
ATOM   2504 C CD  . PRO B 2 119 ? -7.69651  14.36857 42.65067  1.000 19.25374  ? 113 PRO L CD  1 
ATOM   2505 N N   . SER B 2 120 ? -10.37319 17.31605 40.30019  1.000 19.92619  ? 114 SER L N   1 
ATOM   2506 C CA  . SER B 2 120 ? -11.78170 17.37929 39.94325  1.000 21.79784  ? 114 SER L CA  1 
ATOM   2507 C C   . SER B 2 120 ? -12.02327 16.27900 38.92192  1.000 19.41543  ? 114 SER L C   1 
ATOM   2508 O O   . SER B 2 120 ? -11.27145 16.16093 37.94866  1.000 20.38625  ? 114 SER L O   1 
ATOM   2509 C CB  . SER B 2 120 ? -12.14712 18.74553 39.35503  1.000 27.79952  ? 114 SER L CB  1 
ATOM   2510 O OG  . SER B 2 120 ? -11.77737 19.78642 40.23196  1.000 32.17360  ? 114 SER L OG  1 
ATOM   2511 N N   . VAL B 2 121 ? -13.04583 15.46118 39.15223  1.000 23.39706  ? 115 VAL L N   1 
ATOM   2512 C CA  . VAL B 2 121 ? -13.30859 14.27533 38.34275  1.000 22.94867  ? 115 VAL L CA  1 
ATOM   2513 C C   . VAL B 2 121 ? -14.59249 14.47766 37.54590  1.000 23.05882  ? 115 VAL L C   1 
ATOM   2514 O O   . VAL B 2 121 ? -15.64015 14.82120 38.10816  1.000 25.10387  ? 115 VAL L O   1 
ATOM   2515 C CB  . VAL B 2 121 ? -13.38149 13.01124 39.21241  1.000 18.64824  ? 115 VAL L CB  1 
ATOM   2516 C CG1 . VAL B 2 121 ? -13.57713 11.77832 38.32299  1.000 24.15724  ? 115 VAL L CG1 1 
ATOM   2517 C CG2 . VAL B 2 121 ? -12.11424 12.87053 40.03729  1.000 20.00195  ? 115 VAL L CG2 1 
ATOM   2518 N N   . PHE B 2 122 ? -14.50571 14.27103 36.23109  1.000 20.00228  ? 116 PHE L N   1 
ATOM   2519 C CA  . PHE B 2 122 ? -15.62637 14.42918 35.31605  1.000 16.72240  ? 116 PHE L CA  1 
ATOM   2520 C C   . PHE B 2 122 ? -15.79092 13.13303 34.53807  1.000 23.17269  ? 116 PHE L C   1 
ATOM   2521 O O   . PHE B 2 122 ? -14.79167 12.49314 34.18778  1.000 17.87434  ? 116 PHE L O   1 
ATOM   2522 C CB  . PHE B 2 122 ? -15.38128 15.58282 34.33437  1.000 20.85139  ? 116 PHE L CB  1 
ATOM   2523 C CG  . PHE B 2 122 ? -15.17004 16.92021 34.99546  1.000 16.95635  ? 116 PHE L CG  1 
ATOM   2524 C CD1 . PHE B 2 122 ? -13.90104 17.34032 35.35488  1.000 17.15846  ? 116 PHE L CD1 1 
ATOM   2525 C CD2 . PHE B 2 122 ? -16.24483 17.75977 35.24215  1.000 19.57347  ? 116 PHE L CD2 1 
ATOM   2526 C CE1 . PHE B 2 122 ? -13.71025 18.57454 35.96121  1.000 20.21917  ? 116 PHE L CE1 1 
ATOM   2527 C CE2 . PHE B 2 122 ? -16.06037 19.00635 35.83871  1.000 21.82094  ? 116 PHE L CE2 1 
ATOM   2528 C CZ  . PHE B 2 122 ? -14.79769 19.41037 36.20929  1.000 22.03995  ? 116 PHE L CZ  1 
ATOM   2529 N N   . ILE B 2 123 ? -17.03397 12.74232 34.25207  1.000 23.30291  ? 117 ILE L N   1 
ATOM   2530 C CA  . ILE B 2 123 ? -17.28198 11.54000 33.45935  1.000 20.64316  ? 117 ILE L CA  1 
ATOM   2531 C C   . ILE B 2 123 ? -18.20843 11.89135 32.30298  1.000 22.75335  ? 117 ILE L C   1 
ATOM   2532 O O   . ILE B 2 123 ? -19.20844 12.59656 32.48490  1.000 22.01945  ? 117 ILE L O   1 
ATOM   2533 C CB  . ILE B 2 123 ? -17.83599 10.37972 34.32130  1.000 19.00814  ? 117 ILE L CB  1 
ATOM   2534 C CG1 . ILE B 2 123 ? -17.98998 9.10492  33.47389  1.000 23.60259  ? 117 ILE L CG1 1 
ATOM   2535 C CG2 . ILE B 2 123 ? -19.16801 10.74977 35.01632  1.000 19.96292  ? 117 ILE L CG2 1 
ATOM   2536 C CD1 . ILE B 2 123 ? -18.29152 7.84705  34.30528  1.000 20.36840  ? 117 ILE L CD1 1 
ATOM   2537 N N   . PHE B 2 124 ? -17.85456 11.43060 31.10494  1.000 16.96182  ? 118 PHE L N   1 
ATOM   2538 C CA  . PHE B 2 124 ? -18.55499 11.80364 29.88280  1.000 14.52021  ? 118 PHE L CA  1 
ATOM   2539 C C   . PHE B 2 124 ? -19.16509 10.55745 29.25908  1.000 23.20853  ? 118 PHE L C   1 
ATOM   2540 O O   . PHE B 2 124 ? -18.43165 9.59547  28.96878  1.000 21.67344  ? 118 PHE L O   1 
ATOM   2541 C CB  . PHE B 2 124 ? -17.61828 12.45293 28.85824  1.000 18.97387  ? 118 PHE L CB  1 
ATOM   2542 C CG  . PHE B 2 124 ? -17.07917 13.78842 29.25800  1.000 21.12550  ? 118 PHE L CG  1 
ATOM   2543 C CD1 . PHE B 2 124 ? -17.82746 14.94421 29.05629  1.000 18.44349  ? 118 PHE L CD1 1 
ATOM   2544 C CD2 . PHE B 2 124 ? -15.80546 13.89868 29.76572  1.000 17.66920  ? 118 PHE L CD2 1 
ATOM   2545 C CE1 . PHE B 2 124 ? -17.32603 16.18225 29.41312  1.000 23.14558  ? 118 PHE L CE1 1 
ATOM   2546 C CE2 . PHE B 2 124 ? -15.29184 15.14238 30.12578  1.000 32.77156  ? 118 PHE L CE2 1 
ATOM   2547 C CZ  . PHE B 2 124 ? -16.05639 16.28939 29.94530  1.000 23.31674  ? 118 PHE L CZ  1 
ATOM   2548 N N   . PRO B 2 125 ? -20.46408 10.52587 29.00961  1.000 19.23177  ? 119 PRO L N   1 
ATOM   2549 C CA  . PRO B 2 125 ? -21.03800 9.41694  28.27031  1.000 21.86053  ? 119 PRO L CA  1 
ATOM   2550 C C   . PRO B 2 125 ? -20.60435 9.48343  26.82031  1.000 20.51396  ? 119 PRO L C   1 
ATOM   2551 O O   . PRO B 2 125 ? -20.14565 10.53686 26.35256  1.000 19.43556  ? 119 PRO L O   1 
ATOM   2552 C CB  . PRO B 2 125 ? -22.55423 9.63849  28.41588  1.000 26.91436  ? 119 PRO L CB  1 
ATOM   2553 C CG  . PRO B 2 125 ? -22.69701 10.43042 29.68202  1.000 23.26099  ? 119 PRO L CG  1 
ATOM   2554 C CD  . PRO B 2 125 ? -21.49949 11.36956 29.63501  1.000 20.72101  ? 119 PRO L CD  1 
ATOM   2555 N N   . PRO B 2 126 ? -20.69814 8.38284  26.08467  1.000 22.87992  ? 120 PRO L N   1 
ATOM   2556 C CA  . PRO B 2 126 ? -20.47632 8.46215  24.63491  1.000 22.54891  ? 120 PRO L CA  1 
ATOM   2557 C C   . PRO B 2 126 ? -21.48823 9.39768  23.99623  1.000 26.73133  ? 120 PRO L C   1 
ATOM   2558 O O   . PRO B 2 126 ? -22.63502 9.50461  24.43875  1.000 20.77555  ? 120 PRO L O   1 
ATOM   2559 C CB  . PRO B 2 126 ? -20.67521 7.01922  24.16206  1.000 22.63953  ? 120 PRO L CB  1 
ATOM   2560 C CG  . PRO B 2 126 ? -21.53219 6.39625  25.21323  1.000 28.95865  ? 120 PRO L CG  1 
ATOM   2561 C CD  . PRO B 2 126 ? -21.12392 7.03854  26.50985  1.000 26.64695  ? 120 PRO L CD  1 
ATOM   2562 N N   . SER B 2 127 ? -21.05154 10.08325 22.94705  1.000 26.87133  ? 121 SER L N   1 
ATOM   2563 C CA  . SER B 2 127 ? -21.96321 10.94166 22.21398  1.000 31.28174  ? 121 SER L CA  1 
ATOM   2564 C C   . SER B 2 127 ? -22.90487 10.09645 21.36142  1.000 27.90504  ? 121 SER L C   1 
ATOM   2565 O O   . SER B 2 127 ? -22.54520 9.01569  20.88559  1.000 30.88764  ? 121 SER L O   1 
ATOM   2566 C CB  . SER B 2 127 ? -21.18389 11.92003 21.34047  1.000 19.61537  ? 121 SER L CB  1 
ATOM   2567 O OG  . SER B 2 127 ? -20.60343 11.25976 20.21729  1.000 22.86148  ? 121 SER L OG  1 
ATOM   2568 N N   . ASP B 2 128 ? -24.13223 10.59584 21.18367  1.000 32.49616  ? 122 ASP L N   1 
ATOM   2569 C CA  . ASP B 2 128 ? -25.06389 9.95574  20.25834  1.000 35.72448  ? 122 ASP L CA  1 
ATOM   2570 C C   . ASP B 2 128 ? -24.44077 9.80604  18.87894  1.000 29.30999  ? 122 ASP L C   1 
ATOM   2571 O O   . ASP B 2 128 ? -24.60796 8.77725  18.21396  1.000 34.51386  ? 122 ASP L O   1 
ATOM   2572 C CB  . ASP B 2 128 ? -26.36149 10.76044 20.17636  1.000 37.74533  ? 122 ASP L CB  1 
ATOM   2573 C CG  . ASP B 2 128 ? -27.14451 10.73576 21.47850  1.000 45.54720  ? 122 ASP L CG  1 
ATOM   2574 O OD1 . ASP B 2 128 ? -27.00652 9.75405  22.24698  1.000 42.75076  ? 122 ASP L OD1 1 
ATOM   2575 O OD2 . ASP B 2 128 ? -27.89896 11.69760 21.73507  1.000 49.41816  ? 122 ASP L OD2 1 
ATOM   2576 N N   . GLU B 2 129 ? -23.68812 10.81752 18.45169  1.000 32.49616  ? 123 GLU L N   1 
ATOM   2577 C CA  . GLU B 2 129 ? -22.98828 10.75961 17.17451  1.000 29.35954  ? 123 GLU L CA  1 
ATOM   2578 C C   . GLU B 2 129 ? -22.10427 9.51111  17.07691  1.000 38.45784  ? 123 GLU L C   1 
ATOM   2579 O O   . GLU B 2 129 ? -22.16732 8.76440  16.08960  1.000 30.20709  ? 123 GLU L O   1 
ATOM   2580 C CB  . GLU B 2 129 ? -22.18026 12.04672 17.01530  1.000 31.97767  ? 123 GLU L CB  1 
ATOM   2581 C CG  . GLU B 2 129 ? -21.49993 12.28332 15.69219  1.000 49.81807  ? 123 GLU L CG  1 
ATOM   2582 C CD  . GLU B 2 129 ? -20.79406 13.63449 15.67540  1.000 54.77123  ? 123 GLU L CD  1 
ATOM   2583 O OE1 . GLU B 2 129 ? -21.17811 14.50747 16.49645  1.000 53.67862  ? 123 GLU L OE1 1 
ATOM   2584 O OE2 . GLU B 2 129 ? -19.85622 13.81524 14.85965  1.000 58.00506  ? 123 GLU L OE2 1 
ATOM   2585 N N   . GLN B 2 130 ? -21.29322 9.24601  18.10963  1.000 28.86593  ? 124 GLN L N   1 
ATOM   2586 C CA  . GLN B 2 130 ? -20.41648 8.07804  18.06368  1.000 26.50486  ? 124 GLN L CA  1 
ATOM   2587 C C   . GLN B 2 130 ? -21.20923 6.77674  18.11957  1.000 28.01378  ? 124 GLN L C   1 
ATOM   2588 O O   . GLN B 2 130 ? -20.85467 5.79762  17.45188  1.000 25.90136  ? 124 GLN L O   1 
ATOM   2589 C CB  . GLN B 2 130 ? -19.39930 8.11099  19.20871  1.000 28.71826  ? 124 GLN L CB  1 
ATOM   2590 C CG  . GLN B 2 130 ? -18.39679 6.94682  19.12080  1.000 27.31482  ? 124 GLN L CG  1 
ATOM   2591 C CD  . GLN B 2 130 ? -17.51383 6.81776  20.34334  1.000 27.49783  ? 124 GLN L CD  1 
ATOM   2592 O OE1 . GLN B 2 130 ? -17.84237 7.33290  21.41343  1.000 20.47167  ? 124 GLN L OE1 1 
ATOM   2593 N NE2 . GLN B 2 130 ? -16.38652 6.10934  20.19523  1.000 20.59926  ? 124 GLN L NE2 1 
ATOM   2594 N N   . LEU B 2 131 ? -22.26944 6.73720  18.92629  1.000 26.50102  ? 125 LEU L N   1 
ATOM   2595 C CA  . LEU B 2 131 ? -23.04554 5.50764  19.05440  1.000 34.04224  ? 125 LEU L CA  1 
ATOM   2596 C C   . LEU B 2 131 ? -23.61828 5.05698  17.71525  1.000 41.19582  ? 125 LEU L C   1 
ATOM   2597 O O   . LEU B 2 131 ? -23.70732 3.84984  17.45823  1.000 40.14776  ? 125 LEU L O   1 
ATOM   2598 C CB  . LEU B 2 131 ? -24.15784 5.69674  20.08058  1.000 38.47213  ? 125 LEU L CB  1 
ATOM   2599 C CG  . LEU B 2 131 ? -23.65261 5.76452  21.51777  1.000 29.97618  ? 125 LEU L CG  1 
ATOM   2600 C CD1 . LEU B 2 131 ? -24.80222 6.07756  22.46899  1.000 29.02118  ? 125 LEU L CD1 1 
ATOM   2601 C CD2 . LEU B 2 131 ? -22.97406 4.44437  21.89134  1.000 28.42341  ? 125 LEU L CD2 1 
ATOM   2602 N N   . LYS B 2 132 ? -23.97737 6.00362  16.83958  1.000 36.74423  ? 126 LYS L N   1 
ATOM   2603 C CA  . LYS B 2 132 ? -24.45508 5.62892  15.51099  1.000 41.16372  ? 126 LYS L CA  1 
ATOM   2604 C C   . LYS B 2 132 ? -23.40332 4.84804  14.72549  1.000 46.68541  ? 126 LYS L C   1 
ATOM   2605 O O   . LYS B 2 132 ? -23.75286 4.01567  13.88219  1.000 49.84332  ? 126 LYS L O   1 
ATOM   2606 C CB  . LYS B 2 132 ? -24.88720 6.87742  14.73862  1.000 45.58417  ? 126 LYS L CB  1 
ATOM   2607 C CG  . LYS B 2 132 ? -26.33699 7.29853  14.99652  1.000 44.99125  ? 126 LYS L CG  1 
ATOM   2608 C CD  . LYS B 2 132 ? -26.48816 8.81859  15.00418  1.000 39.09656  ? 126 LYS L CD  1 
ATOM   2609 C CE  . LYS B 2 132 ? -25.87013 9.45460  13.75987  1.000 45.65134  ? 126 LYS L CE  1 
ATOM   2610 N NZ  . LYS B 2 132 ? -25.76868 10.94477 13.87305  1.000 45.21956  ? 126 LYS L NZ  1 
ATOM   2611 N N   . SER B 2 133 ? -22.11854 5.08856  14.99126  1.000 42.83336  ? 127 SER L N   1 
ATOM   2612 C CA  . SER B 2 133 ? -21.03608 4.38746  14.30944  1.000 38.23343  ? 127 SER L CA  1 
ATOM   2613 C C   . SER B 2 133 ? -20.81317 2.96691  14.81889  1.000 39.32039  ? 127 SER L C   1 
ATOM   2614 O O   . SER B 2 133 ? -20.00542 2.24360  14.23057  1.000 44.34076  ? 127 SER L O   1 
ATOM   2615 C CB  . SER B 2 133 ? -19.72564 5.16922  14.45374  1.000 41.41670  ? 127 SER L CB  1 
ATOM   2616 O OG  . SER B 2 133 ? -19.07354 4.83955  15.68179  1.000 47.72923  ? 127 SER L OG  1 
ATOM   2617 N N   . GLY B 2 134 ? -21.46439 2.55982  15.90231  1.000 32.30459  ? 128 GLY L N   1 
ATOM   2618 C CA  . GLY B 2 134 ? -21.27764 1.23104  16.45055  1.000 36.12628  ? 128 GLY L CA  1 
ATOM   2619 C C   . GLY B 2 134 ? -20.29049 1.09176  17.59711  1.000 37.51273  ? 128 GLY L C   1 
ATOM   2620 O O   . GLY B 2 134 ? -20.01831 -0.04200 18.01691  1.000 36.84594  ? 128 GLY L O   1 
ATOM   2621 N N   . THR B 2 135 ? -19.75473 2.19405  18.12512  1.000 35.79078  ? 129 THR L N   1 
ATOM   2622 C CA  . THR B 2 135 ? -18.75604 2.14873  19.18612  1.000 33.22607  ? 129 THR L CA  1 
ATOM   2623 C C   . THR B 2 135 ? -19.12170 3.14603  20.27327  1.000 28.27616  ? 129 THR L C   1 
ATOM   2624 O O   . THR B 2 135 ? -19.76879 4.16132  20.00638  1.000 36.60230  ? 129 THR L O   1 
ATOM   2625 C CB  . THR B 2 135 ? -17.33751 2.45442  18.64715  1.000 28.22897  ? 129 THR L CB  1 
ATOM   2626 O OG1 . THR B 2 135 ? -17.03011 1.54487  17.58813  1.000 43.71197  ? 129 THR L OG1 1 
ATOM   2627 C CG2 . THR B 2 135 ? -16.27927 2.28902  19.74381  1.000 31.87207  ? 129 THR L CG2 1 
ATOM   2628 N N   . ALA B 2 136 ? -18.70677 2.85033  21.50685  1.000 24.98693  ? 130 ALA L N   1 
ATOM   2629 C CA  . ALA B 2 136 ? -18.95757 3.73054  22.64352  1.000 26.73154  ? 130 ALA L CA  1 
ATOM   2630 C C   . ALA B 2 136 ? -17.66281 3.93849  23.41054  1.000 27.80412  ? 130 ALA L C   1 
ATOM   2631 O O   . ALA B 2 136 ? -17.11542 2.98126  23.96204  1.000 25.05891  ? 130 ALA L O   1 
ATOM   2632 C CB  . ALA B 2 136 ? -20.02769 3.15253  23.57198  1.000 25.98793  ? 130 ALA L CB  1 
ATOM   2633 N N   . SER B 2 137 ? -17.19899 5.18864  23.46617  1.000 21.69132  ? 131 SER L N   1 
ATOM   2634 C CA  . SER B 2 137 ? -16.08493 5.60425  24.30853  1.000 23.77541  ? 131 SER L CA  1 
ATOM   2635 C C   . SER B 2 137 ? -16.62813 6.36716  25.51486  1.000 23.61049  ? 131 SER L C   1 
ATOM   2636 O O   . SER B 2 137 ? -17.26658 7.41574  25.35290  1.000 22.47514  ? 131 SER L O   1 
ATOM   2637 C CB  . SER B 2 137 ? -15.11607 6.49432  23.52896  1.000 25.12002  ? 131 SER L CB  1 
ATOM   2638 O OG  . SER B 2 137 ? -14.70155 5.90037  22.31976  1.000 23.88718  ? 131 SER L OG  1 
ATOM   2639 N N   . VAL B 2 138 ? -16.36249 5.85736  26.71615  1.000 18.11713  ? 132 VAL L N   1 
ATOM   2640 C CA  . VAL B 2 138 ? -16.67249 6.55837  27.96109  1.000 21.01428  ? 132 VAL L CA  1 
ATOM   2641 C C   . VAL B 2 138 ? -15.38387 7.15587  28.50087  1.000 20.08565  ? 132 VAL L C   1 
ATOM   2642 O O   . VAL B 2 138 ? -14.39847 6.43393  28.69699  1.000 16.92819  ? 132 VAL L O   1 
ATOM   2643 C CB  . VAL B 2 138 ? -17.30526 5.61274  28.99744  1.000 20.01474  ? 132 VAL L CB  1 
ATOM   2644 C CG1 . VAL B 2 138 ? -17.91685 6.42968  30.12306  1.000 19.82909  ? 132 VAL L CG1 1 
ATOM   2645 C CG2 . VAL B 2 138 ? -18.35946 4.75056  28.32294  1.000 23.07860  ? 132 VAL L CG2 1 
ATOM   2646 N N   . VAL B 2 139 ? -15.38024 8.46802  28.74888  1.000 20.18843  ? 133 VAL L N   1 
ATOM   2647 C CA  . VAL B 2 139 ? -14.16343 9.18397  29.13501  1.000 14.85665  ? 133 VAL L CA  1 
ATOM   2648 C C   . VAL B 2 139 ? -14.30435 9.66903  30.56771  1.000 20.62004  ? 133 VAL L C   1 
ATOM   2649 O O   . VAL B 2 139 ? -15.29479 10.32542 30.91415  1.000 20.52172  ? 133 VAL L O   1 
ATOM   2650 C CB  . VAL B 2 139 ? -13.86037 10.36909 28.20083  1.000 18.30207  ? 133 VAL L CB  1 
ATOM   2651 C CG1 . VAL B 2 139 ? -12.60339 11.09813 28.68200  1.000 18.92672  ? 133 VAL L CG1 1 
ATOM   2652 C CG2 . VAL B 2 139 ? -13.68387 9.90508  26.75857  1.000 15.46729  ? 133 VAL L CG2 1 
ATOM   2653 N N   . CYS B 2 140 ? -13.30409 9.35418  31.38934  1.000 19.32307  ? 134 CYS L N   1 
ATOM   2654 C CA  . CYS B 2 140 ? -13.15235 9.87530  32.74044  1.000 17.61764  ? 134 CYS L CA  1 
ATOM   2655 C C   . CYS B 2 140 ? -11.99200 10.85621 32.72478  1.000 18.38510  ? 134 CYS L C   1 
ATOM   2656 O O   . CYS B 2 140 ? -10.91432 10.53073 32.21819  1.000 21.95180  ? 134 CYS L O   1 
ATOM   2657 C CB  . CYS B 2 140 ? -12.86955 8.73339  33.72065  1.000 16.15509  ? 134 CYS L CB  1 
ATOM   2658 S SG  . CYS B 2 140 ? -12.79473 9.13849  35.50697  1.000 28.00953  ? 134 CYS L SG  1 
ATOM   2659 N N   . LEU B 2 141 ? -12.20619 12.04722 33.26478  1.000 17.59581  ? 135 LEU L N   1 
ATOM   2660 C CA  . LEU B 2 141 ? -11.18947 13.09003 33.29958  1.000 15.12480  ? 135 LEU L CA  1 
ATOM   2661 C C   . LEU B 2 141 ? -10.84768 13.45452 34.74083  1.000 21.14257  ? 135 LEU L C   1 
ATOM   2662 O O   . LEU B 2 141 ? -11.74126 13.74566 35.54241  1.000 20.18485  ? 135 LEU L O   1 
ATOM   2663 C CB  . LEU B 2 141 ? -11.66626 14.34253 32.56180  1.000 16.57005  ? 135 LEU L CB  1 
ATOM   2664 C CG  . LEU B 2 141 ? -10.89697 15.62791 32.86025  1.000 17.07932  ? 135 LEU L CG  1 
ATOM   2665 C CD1 . LEU B 2 141 ? -9.47774  15.57117 32.31643  1.000 15.39446  ? 135 LEU L CD1 1 
ATOM   2666 C CD2 . LEU B 2 141 ? -11.65365 16.80618 32.28753  1.000 14.77992  ? 135 LEU L CD2 1 
ATOM   2667 N N   . LEU B 2 142 ? -9.55488  13.45806 35.04832  1.000 16.05067  ? 136 LEU L N   1 
ATOM   2668 C CA  . LEU B 2 142 ? -9.00536  13.87276 36.33868  1.000 18.91047  ? 136 LEU L CA  1 
ATOM   2669 C C   . LEU B 2 142 ? -8.26133  15.16659 36.07533  1.000 19.87000  ? 136 LEU L C   1 
ATOM   2670 O O   . LEU B 2 142 ? -7.20362  15.15559 35.43269  1.000 19.50191  ? 136 LEU L O   1 
ATOM   2671 C CB  . LEU B 2 142 ? -8.04989  12.82398 36.90745  1.000 18.17274  ? 136 LEU L CB  1 
ATOM   2672 C CG  . LEU B 2 142 ? -8.58506  11.54294 37.54230  1.000 20.51750  ? 136 LEU L CG  1 
ATOM   2673 C CD1 . LEU B 2 142 ? -9.38919  10.70930 36.55379  1.000 23.64157  ? 136 LEU L CD1 1 
ATOM   2674 C CD2 . LEU B 2 142 ? -7.42814  10.72172 38.10332  1.000 20.22841  ? 136 LEU L CD2 1 
ATOM   2675 N N   . ASN B 2 143 ? -8.79697  16.27642 36.55445  1.000 17.43249  ? 137 ASN L N   1 
ATOM   2676 C CA  . ASN B 2 143 ? -8.28717  17.58404 36.16642  1.000 22.21496  ? 137 ASN L CA  1 
ATOM   2677 C C   . ASN B 2 143 ? -7.49467  18.21976 37.30742  1.000 27.57834  ? 137 ASN L C   1 
ATOM   2678 O O   . ASN B 2 143 ? -8.00240  18.34084 38.42691  1.000 21.17702  ? 137 ASN L O   1 
ATOM   2679 C CB  . ASN B 2 143 ? -9.44035  18.48557 35.73810  1.000 19.75841  ? 137 ASN L CB  1 
ATOM   2680 C CG  . ASN B 2 143 ? -8.98576  19.62544 34.84630  1.000 28.88081  ? 137 ASN L CG  1 
ATOM   2681 O OD1 . ASN B 2 143 ? -8.28555  19.41481 33.86227  1.000 29.33601  ? 137 ASN L OD1 1 
ATOM   2682 N ND2 . ASN B 2 143 ? -9.36397  20.83759 35.20553  1.000 34.30994  ? 137 ASN L ND2 1 
ATOM   2683 N N   . ASN B 2 144 ? -6.24475  18.59835 37.01501  1.000 19.93686  ? 138 ASN L N   1 
ATOM   2684 C CA  . ASN B 2 144 ? -5.39614  19.46069 37.84921  1.000 22.80651  ? 138 ASN L CA  1 
ATOM   2685 C C   . ASN B 2 144 ? -5.15962  18.86161 39.24112  1.000 24.71457  ? 138 ASN L C   1 
ATOM   2686 O O   . ASN B 2 144 ? -5.58561  19.40250 40.26360  1.000 27.80617  ? 138 ASN L O   1 
ATOM   2687 C CB  . ASN B 2 144 ? -5.99905  20.86685 37.96835  1.000 20.75153  ? 138 ASN L CB  1 
ATOM   2688 C CG  . ASN B 2 144 ? -6.18961  21.53180 36.62860  1.000 33.46544  ? 138 ASN L CG  1 
ATOM   2689 O OD1 . ASN B 2 144 ? -5.62899  21.10407 35.62288  1.000 32.26049  ? 138 ASN L OD1 1 
ATOM   2690 N ND2 . ASN B 2 144 ? -6.99545  22.58734 36.60420  1.000 38.15344  ? 138 ASN L ND2 1 
ATOM   2691 N N   . PHE B 2 145 ? -4.43639  17.74492 39.26283  1.000 17.07088  ? 139 PHE L N   1 
ATOM   2692 C CA  . PHE B 2 145 ? -4.11752  17.06793 40.51412  1.000 21.08875  ? 139 PHE L CA  1 
ATOM   2693 C C   . PHE B 2 145 ? -2.60597  16.88790 40.65943  1.000 22.09212  ? 139 PHE L C   1 
ATOM   2694 O O   . PHE B 2 145 ? -1.83673  17.01642 39.69737  1.000 21.95865  ? 139 PHE L O   1 
ATOM   2695 C CB  . PHE B 2 145 ? -4.83573  15.70446 40.63237  1.000 19.92001  ? 139 PHE L CB  1 
ATOM   2696 C CG  . PHE B 2 145 ? -4.38996  14.66674 39.61482  1.000 22.31191  ? 139 PHE L CG  1 
ATOM   2697 C CD1 . PHE B 2 145 ? -4.96037  14.61856 38.35584  1.000 21.31407  ? 139 PHE L CD1 1 
ATOM   2698 C CD2 . PHE B 2 145 ? -3.41814  13.72982 39.93913  1.000 25.34375  ? 139 PHE L CD2 1 
ATOM   2699 C CE1 . PHE B 2 145 ? -4.54397  13.66536 37.41318  1.000 17.82626  ? 139 PHE L CE1 1 
ATOM   2700 C CE2 . PHE B 2 145 ? -3.00413  12.77065 39.02243  1.000 24.03732  ? 139 PHE L CE2 1 
ATOM   2701 C CZ  . PHE B 2 145 ? -3.57056  12.74266 37.75206  1.000 21.39015  ? 139 PHE L CZ  1 
ATOM   2702 N N   . TYR B 2 146 ? -2.19060  16.59807 41.89647  1.000 22.42104  ? 140 TYR L N   1 
ATOM   2703 C CA  . TYR B 2 146 ? -0.81131  16.31488 42.29841  1.000 25.09283  ? 140 TYR L CA  1 
ATOM   2704 C C   . TYR B 2 146 ? -0.87081  15.46836 43.56516  1.000 25.65317  ? 140 TYR L C   1 
ATOM   2705 O O   . TYR B 2 146 ? -1.69017  15.75536 44.44295  1.000 26.53342  ? 140 TYR L O   1 
ATOM   2706 C CB  . TYR B 2 146 ? -0.02083  17.60395 42.55993  1.000 19.38751  ? 140 TYR L CB  1 
ATOM   2707 C CG  . TYR B 2 146 ? 1.44365   17.34100 42.72168  1.000 28.61559  ? 140 TYR L CG  1 
ATOM   2708 C CD1 . TYR B 2 146 ? 2.29354   17.33533 41.61366  1.000 23.79749  ? 140 TYR L CD1 1 
ATOM   2709 C CD2 . TYR B 2 146 ? 1.98585   17.06664 43.97247  1.000 25.29448  ? 140 TYR L CD2 1 
ATOM   2710 C CE1 . TYR B 2 146 ? 3.63429   17.08121 41.75052  1.000 26.50086  ? 140 TYR L CE1 1 
ATOM   2711 C CE2 . TYR B 2 146 ? 3.31974   16.80685 44.11694  1.000 25.58456  ? 140 TYR L CE2 1 
ATOM   2712 C CZ  . TYR B 2 146 ? 4.14454   16.81874 43.01561  1.000 32.91848  ? 140 TYR L CZ  1 
ATOM   2713 O OH  . TYR B 2 146 ? 5.48055   16.55184 43.17498  1.000 31.44519  ? 140 TYR L OH  1 
ATOM   2714 N N   . PRO B 2 147 ? -0.03382  14.43567 43.70337  1.000 28.53483  ? 141 PRO L N   1 
ATOM   2715 C CA  . PRO B 2 147 ? 0.99492   14.01288 42.75479  1.000 26.09373  ? 141 PRO L CA  1 
ATOM   2716 C C   . PRO B 2 147 ? 0.41804   13.19792 41.61783  1.000 26.77131  ? 141 PRO L C   1 
ATOM   2717 O O   . PRO B 2 147 ? -0.79631  13.00078 41.54017  1.000 21.25852  ? 141 PRO L O   1 
ATOM   2718 C CB  . PRO B 2 147 ? 1.93260   13.16508 43.61772  1.000 24.36591  ? 141 PRO L CB  1 
ATOM   2719 C CG  . PRO B 2 147 ? 1.02099   12.55503 44.63605  1.000 33.20589  ? 141 PRO L CG  1 
ATOM   2720 C CD  . PRO B 2 147 ? -0.04693  13.58247 44.90794  1.000 28.15607  ? 141 PRO L CD  1 
ATOM   2721 N N   . ARG B 2 148 ? 1.31299   12.68726 40.77294  1.000 24.85754  ? 142 ARG L N   1 
ATOM   2722 C CA  . ARG B 2 148 ? 0.89843   12.05530 39.52239  1.000 32.37740  ? 142 ARG L CA  1 
ATOM   2723 C C   . ARG B 2 148 ? 0.28103   10.67956 39.75354  1.000 29.20869  ? 142 ARG L C   1 
ATOM   2724 O O   . ARG B 2 148 ? -0.67656  10.29687 39.06976  1.000 23.83411  ? 142 ARG L O   1 
ATOM   2725 C CB  . ARG B 2 148 ? 2.10795   11.95845 38.59907  1.000 36.61195  ? 142 ARG L CB  1 
ATOM   2726 C CG  . ARG B 2 148 ? 1.82635   11.57309 37.16183  1.000 34.95132  ? 142 ARG L CG  1 
ATOM   2727 C CD  . ARG B 2 148 ? 3.14308   11.63017 36.38291  1.000 46.37253  ? 142 ARG L CD  1 
ATOM   2728 N NE  . ARG B 2 148 ? 3.03423   11.02126 35.06621  1.000 49.78094  ? 142 ARG L NE  1 
ATOM   2729 C CZ  . ARG B 2 148 ? 3.11537   9.71683  34.84505  1.000 62.69739  ? 142 ARG L CZ  1 
ATOM   2730 N NH1 . ARG B 2 148 ? 3.33316   8.86196  35.83254  1.000 64.88327  ? 142 ARG L NH1 1 
ATOM   2731 N NH2 . ARG B 2 148 ? 2.96474   9.25770  33.60409  1.000 65.47592  ? 142 ARG L NH2 1 
ATOM   2732 N N   . GLU B 2 149 ? 0.81487   9.92034  40.69970  1.000 31.41128  ? 143 GLU L N   1 
ATOM   2733 C CA  . GLU B 2 149 ? 0.36681   8.54995  40.90632  1.000 31.89468  ? 143 GLU L CA  1 
ATOM   2734 C C   . GLU B 2 149 ? -1.10075  8.53475  41.30672  1.000 33.49065  ? 143 GLU L C   1 
ATOM   2735 O O   . GLU B 2 149 ? -1.49633  9.18236  42.28087  1.000 27.34866  ? 143 GLU L O   1 
ATOM   2736 C CB  . GLU B 2 149 ? 1.22142   7.86834  41.97792  1.000 37.42980  ? 143 GLU L CB  1 
ATOM   2737 C CG  . GLU B 2 149 ? 2.71674   8.05313  41.78015  1.000 48.98017  ? 143 GLU L CG  1 
ATOM   2738 C CD  . GLU B 2 149 ? 3.24176   9.33196  42.42695  1.000 53.35724  ? 143 GLU L CD  1 
ATOM   2739 O OE1 . GLU B 2 149 ? 3.47272   9.32572  43.66125  1.000 58.68874  ? 143 GLU L OE1 1 
ATOM   2740 O OE2 . GLU B 2 149 ? 3.40880   10.34203 41.70207  1.000 49.28550  ? 143 GLU L OE2 1 
ATOM   2741 N N   . ALA B 2 150 ? -1.90955  7.82094  40.52988  1.000 27.97209  ? 144 ALA L N   1 
ATOM   2742 C CA  . ALA B 2 150 ? -3.31021  7.60461  40.85384  1.000 26.40615  ? 144 ALA L CA  1 
ATOM   2743 C C   . ALA B 2 150 ? -3.73160  6.29052  40.22342  1.000 31.28803  ? 144 ALA L C   1 
ATOM   2744 O O   . ALA B 2 150 ? -3.18532  5.88045  39.19567  1.000 28.70294  ? 144 ALA L O   1 
ATOM   2745 C CB  . ALA B 2 150 ? -4.19582  8.75341  40.36293  1.000 26.96535  ? 144 ALA L CB  1 
ATOM   2746 N N   . LYS B 2 151 ? -4.67383  5.61311  40.86774  1.000 21.53255  ? 145 LYS L N   1 
ATOM   2747 C CA  . LYS B 2 151 ? -5.24602  4.38180  40.34580  1.000 21.07154  ? 145 LYS L CA  1 
ATOM   2748 C C   . LYS B 2 151 ? -6.67331  4.66673  39.90037  1.000 25.54969  ? 145 LYS L C   1 
ATOM   2749 O O   . LYS B 2 151 ? -7.49390  5.15365  40.69056  1.000 22.55557  ? 145 LYS L O   1 
ATOM   2750 C CB  . LYS B 2 151 ? -5.19910  3.26658  41.38719  1.000 23.85165  ? 145 LYS L CB  1 
ATOM   2751 C CG  . LYS B 2 151 ? -6.10931  2.09170  41.09930  1.000 30.88010  ? 145 LYS L CG  1 
ATOM   2752 C CD  . LYS B 2 151 ? -5.68559  0.88080  41.92492  1.000 41.58767  ? 145 LYS L CD  1 
ATOM   2753 C CE  . LYS B 2 151 ? -6.87274  0.04198  42.39158  1.000 50.85655  ? 145 LYS L CE  1 
ATOM   2754 N NZ  . LYS B 2 151 ? -7.46672  0.54672  43.67515  1.000 51.45696  ? 145 LYS L NZ  1 
ATOM   2755 N N   . VAL B 2 152 ? -6.96058  4.38335  38.63268  1.000 22.91599  ? 146 VAL L N   1 
ATOM   2756 C CA  . VAL B 2 152 ? -8.25727  4.67452  38.03306  1.000 17.28992  ? 146 VAL L CA  1 
ATOM   2757 C C   . VAL B 2 152 ? -8.86855  3.36537  37.55406  1.000 25.61601  ? 146 VAL L C   1 
ATOM   2758 O O   . VAL B 2 152 ? -8.29561  2.68307  36.69409  1.000 28.63269  ? 146 VAL L O   1 
ATOM   2759 C CB  . VAL B 2 152 ? -8.12966  5.68402  36.88642  1.000 26.41304  ? 146 VAL L CB  1 
ATOM   2760 C CG1 . VAL B 2 152 ? -9.49799  6.05717  36.36832  1.000 21.90827  ? 146 VAL L CG1 1 
ATOM   2761 C CG2 . VAL B 2 152 ? -7.37200  6.94092  37.36928  1.000 23.77935  ? 146 VAL L CG2 1 
ATOM   2762 N N   . SER B 2 153 ? -10.03062 3.01832  38.09843  1.000 21.45322  ? 147 SER L N   1 
ATOM   2763 C CA  . SER B 2 153 ? -10.71532 1.77769  37.75182  1.000 24.13219  ? 147 SER L CA  1 
ATOM   2764 C C   . SER B 2 153 ? -12.10043 2.08260  37.20582  1.000 22.24774  ? 147 SER L C   1 
ATOM   2765 O O   . SER B 2 153 ? -12.76826 3.00020  37.68499  1.000 24.43237  ? 147 SER L O   1 
ATOM   2766 C CB  . SER B 2 153 ? -10.84852 0.85928  38.97040  1.000 24.63424  ? 147 SER L CB  1 
ATOM   2767 O OG  . SER B 2 153 ? -9.63753  0.79904  39.69055  1.000 32.96533  ? 147 SER L OG  1 
ATOM   2768 N N   . TRP B 2 154 ? -12.52989 1.30200  36.20935  1.000 18.76249  ? 148 TRP L N   1 
ATOM   2769 C CA  . TRP B 2 154 ? -13.87018 1.39786  35.65654  1.000 21.48536  ? 148 TRP L CA  1 
ATOM   2770 C C   . TRP B 2 154 ? -14.78470 0.33120  36.24427  1.000 26.62181  ? 148 TRP L C   1 
ATOM   2771 O O   . TRP B 2 154 ? -14.37869 -0.82023 36.42809  1.000 23.08856  ? 148 TRP L O   1 
ATOM   2772 C CB  . TRP B 2 154 ? -13.84207 1.25858  34.13514  1.000 21.12725  ? 148 TRP L CB  1 
ATOM   2773 C CG  . TRP B 2 154 ? -13.35850 2.47934  33.46015  1.000 16.12923  ? 148 TRP L CG  1 
ATOM   2774 C CD1 . TRP B 2 154 ? -12.08977 2.73360  33.04838  1.000 20.98009  ? 148 TRP L CD1 1 
ATOM   2775 C CD2 . TRP B 2 154 ? -14.13147 3.63684  33.13223  1.000 19.18656  ? 148 TRP L CD2 1 
ATOM   2776 N NE1 . TRP B 2 154 ? -12.02155 3.97410  32.47038  1.000 20.45537  ? 148 TRP L NE1 1 
ATOM   2777 C CE2 . TRP B 2 154 ? -13.26106 4.55554  32.51704  1.000 21.06711  ? 148 TRP L CE2 1 
ATOM   2778 C CE3 . TRP B 2 154 ? -15.47275 3.98940  33.30896  1.000 18.99362  ? 148 TRP L CE3 1 
ATOM   2779 C CZ2 . TRP B 2 154 ? -13.68710 5.80090  32.06265  1.000 22.78587  ? 148 TRP L CZ2 1 
ATOM   2780 C CZ3 . TRP B 2 154 ? -15.89880 5.22755  32.86283  1.000 23.16071  ? 148 TRP L CZ3 1 
ATOM   2781 C CH2 . TRP B 2 154 ? -15.00728 6.12141  32.24378  1.000 21.45189  ? 148 TRP L CH2 1 
ATOM   2782 N N   . TYR B 2 155 ? -16.02880 0.72408  36.51574  1.000 23.65206  ? 149 TYR L N   1 
ATOM   2783 C CA  . TYR B 2 155 ? -17.08322 -0.17539 36.97254  1.000 28.52593  ? 149 TYR L CA  1 
ATOM   2784 C C   . TYR B 2 155 ? -18.31084 -0.00253 36.09219  1.000 30.89048  ? 149 TYR L C   1 
ATOM   2785 O O   . TYR B 2 155 ? -18.79442 1.11964  35.91247  1.000 30.66342  ? 149 TYR L O   1 
ATOM   2786 C CB  . TYR B 2 155 ? -17.46275 0.09764  38.43170  1.000 26.03334  ? 149 TYR L CB  1 
ATOM   2787 C CG  . TYR B 2 155 ? -16.40765 -0.34120 39.41020  1.000 28.81136  ? 149 TYR L CG  1 
ATOM   2788 C CD1 . TYR B 2 155 ? -16.39804 -1.63802 39.90974  1.000 32.27119  ? 149 TYR L CD1 1 
ATOM   2789 C CD2 . TYR B 2 155 ? -15.41037 0.52892  39.82375  1.000 25.18280  ? 149 TYR L CD2 1 
ATOM   2790 C CE1 . TYR B 2 155 ? -15.42342 -2.05708 40.80549  1.000 36.48845  ? 149 TYR L CE1 1 
ATOM   2791 C CE2 . TYR B 2 155 ? -14.42516 0.11788  40.71723  1.000 31.48309  ? 149 TYR L CE2 1 
ATOM   2792 C CZ  . TYR B 2 155 ? -14.44472 -1.17565 41.20514  1.000 30.67555  ? 149 TYR L CZ  1 
ATOM   2793 O OH  . TYR B 2 155 ? -13.48280 -1.58507 42.09083  1.000 41.66428  ? 149 TYR L OH  1 
ATOM   2794 N N   . VAL B 2 156 ? -18.81773 -1.11026 35.56047  1.000 25.97338  ? 150 VAL L N   1 
ATOM   2795 C CA  . VAL B 2 156 ? -20.04555 -1.13233 34.77849  1.000 28.23336  ? 150 VAL L CA  1 
ATOM   2796 C C   . VAL B 2 156 ? -21.03025 -2.04280 35.50867  1.000 40.09425  ? 150 VAL L C   1 
ATOM   2797 O O   . VAL B 2 156 ? -20.79226 -3.25493 35.63010  1.000 31.96914  ? 150 VAL L O   1 
ATOM   2798 C CB  . VAL B 2 156 ? -19.79892 -1.61402 33.34546  1.000 24.58329  ? 150 VAL L CB  1 
ATOM   2799 C CG1 . VAL B 2 156 ? -21.10562 -1.68440 32.56542  1.000 30.22343  ? 150 VAL L CG1 1 
ATOM   2800 C CG2 . VAL B 2 156 ? -18.79891 -0.69155 32.63088  1.000 25.91893  ? 150 VAL L CG2 1 
ATOM   2801 N N   . ASP B 2 157 ? -22.13872 -1.45875 35.98388  1.000 37.62074  ? 151 ASP L N   1 
ATOM   2802 C CA  . ASP B 2 157 ? -23.11279 -2.15105 36.84148  1.000 37.49920  ? 151 ASP L CA  1 
ATOM   2803 C C   . ASP B 2 157 ? -22.41160 -2.91147 37.97103  1.000 45.12639  ? 151 ASP L C   1 
ATOM   2804 O O   . ASP B 2 157 ? -22.75731 -4.05092 38.29586  1.000 41.83541  ? 151 ASP L O   1 
ATOM   2805 C CB  . ASP B 2 157 ? -24.02137 -3.08278 36.02726  1.000 34.71208  ? 151 ASP L CB  1 
ATOM   2806 C CG  . ASP B 2 157 ? -25.08650 -2.31972 35.20547  1.000 41.14411  ? 151 ASP L CG  1 
ATOM   2807 O OD1 . ASP B 2 157 ? -25.47373 -1.18701 35.57923  1.000 39.30049  ? 151 ASP L OD1 1 
ATOM   2808 O OD2 . ASP B 2 157 ? -25.54523 -2.85993 34.18181  1.000 47.14964  ? 151 ASP L OD2 1 
ATOM   2809 N N   . ASN B 2 158 ? -21.39876 -2.26756 38.56071  1.000 45.44220  ? 152 ASN L N   1 
ATOM   2810 C CA  . ASN B 2 158 ? -20.64575 -2.70459 39.73983  1.000 43.78642  ? 152 ASN L CA  1 
ATOM   2811 C C   . ASN B 2 158 ? -19.70207 -3.86689 39.47217  1.000 38.29859  ? 152 ASN L C   1 
ATOM   2812 O O   . ASN B 2 158 ? -19.14807 -4.43323 40.41905  1.000 43.13317  ? 152 ASN L O   1 
ATOM   2813 C CB  . ASN B 2 158 ? -21.57603 -3.04286 40.90743  1.000 39.91486  ? 152 ASN L CB  1 
ATOM   2814 C CG  . ASN B 2 158 ? -22.27708 -1.81790 41.43355  1.000 47.06198  ? 152 ASN L CG  1 
ATOM   2815 O OD1 . ASN B 2 158 ? -23.50201 -1.70150 41.35179  1.000 56.53494  ? 152 ASN L OD1 1 
ATOM   2816 N ND2 . ASN B 2 158 ? -21.49562 -0.86683 41.94110  1.000 40.07112  ? 152 ASN L ND2 1 
ATOM   2817 N N   . ALA B 2 159 ? -19.47890 -4.21688 38.21381  1.000 36.14594  ? 153 ALA L N   1 
ATOM   2818 C CA  . ALA B 2 159 ? -18.45564 -5.17753 37.82724  1.000 32.56853  ? 153 ALA L CA  1 
ATOM   2819 C C   . ALA B 2 159 ? -17.20050 -4.43390 37.39075  1.000 34.59720  ? 153 ALA L C   1 
ATOM   2820 O O   . ALA B 2 159 ? -17.26742 -3.55335 36.52376  1.000 33.83590  ? 153 ALA L O   1 
ATOM   2821 C CB  . ALA B 2 159 ? -18.95515 -6.07136 36.68995  1.000 33.75810  ? 153 ALA L CB  1 
ATOM   2822 N N   . LEU B 2 160 ? -16.06121 -4.80365 37.97494  1.000 34.71741  ? 154 LEU L N   1 
ATOM   2823 C CA  . LEU B 2 160 ? -14.79221 -4.16929 37.64118  1.000 33.94516  ? 154 LEU L CA  1 
ATOM   2824 C C   . LEU B 2 160 ? -14.34484 -4.56008 36.23753  1.000 34.43252  ? 154 LEU L C   1 
ATOM   2825 O O   . LEU B 2 160 ? -14.30708 -5.74463 35.89457  1.000 35.17190  ? 154 LEU L O   1 
ATOM   2826 C CB  . LEU B 2 160 ? -13.73062 -4.56337 38.66363  1.000 28.19962  ? 154 LEU L CB  1 
ATOM   2827 C CG  . LEU B 2 160 ? -12.26315 -4.22494 38.37525  1.000 32.80995  ? 154 LEU L CG  1 
ATOM   2828 C CD1 . LEU B 2 160 ? -12.00063 -2.72774 38.42021  1.000 28.35711  ? 154 LEU L CD1 1 
ATOM   2829 C CD2 . LEU B 2 160 ? -11.38328 -4.93451 39.39456  1.000 28.19341  ? 154 LEU L CD2 1 
ATOM   2830 N N   . GLN B 2 161 ? -13.98762 -3.56141 35.43051  1.000 23.46455  ? 155 GLN L N   1 
ATOM   2831 C CA  . GLN B 2 161 ? -13.54908 -3.77850 34.05905  1.000 28.02955  ? 155 GLN L CA  1 
ATOM   2832 C C   . GLN B 2 161 ? -12.04268 -3.99100 34.00176  1.000 30.23508  ? 155 GLN L C   1 
ATOM   2833 O O   . GLN B 2 161 ? -11.28986 -3.43487 34.79707  1.000 28.07893  ? 155 GLN L O   1 
ATOM   2834 C CB  . GLN B 2 161 ? -13.92649 -2.58571 33.17257  1.000 24.50754  ? 155 GLN L CB  1 
ATOM   2835 C CG  . GLN B 2 161 ? -15.41319 -2.27265 33.20330  1.000 27.49958  ? 155 GLN L CG  1 
ATOM   2836 C CD  . GLN B 2 161 ? -16.23759 -3.45005 32.70879  1.000 29.91081  ? 155 GLN L CD  1 
ATOM   2837 O OE1 . GLN B 2 161 ? -16.21197 -3.77435 31.52431  1.000 31.59525  ? 155 GLN L OE1 1 
ATOM   2838 N NE2 . GLN B 2 161 ? -16.94503 -4.11356 33.62099  1.000 28.47342  ? 155 GLN L NE2 1 
ATOM   2839 N N   . SER B 2 162 ? -11.60870 -4.79029 33.03150  1.000 29.76089  ? 156 SER L N   1 
ATOM   2840 C CA  . SER B 2 162 ? -10.19705 -5.06915 32.81367  1.000 33.00399  ? 156 SER L CA  1 
ATOM   2841 C C   . SER B 2 162 ? -9.93763  -5.16547 31.31634  1.000 34.70252  ? 156 SER L C   1 
ATOM   2842 O O   . SER B 2 162 ? -10.72516 -5.77290 30.59013  1.000 33.32998  ? 156 SER L O   1 
ATOM   2843 C CB  . SER B 2 162 ? -9.78050  -6.37721 33.50632  1.000 37.78773  ? 156 SER L CB  1 
ATOM   2844 O OG  . SER B 2 162 ? -8.38149  -6.57102 33.43470  1.000 56.52522  ? 156 SER L OG  1 
ATOM   2845 N N   . GLY B 2 163 ? -8.85899  -4.53057 30.84921  1.000 27.92892  ? 157 GLY L N   1 
ATOM   2846 C CA  . GLY B 2 163 ? -8.40050  -4.70910 29.48371  1.000 26.45696  ? 157 GLY L CA  1 
ATOM   2847 C C   . GLY B 2 163 ? -9.12564  -3.92139 28.41072  1.000 34.32716  ? 157 GLY L C   1 
ATOM   2848 O O   . GLY B 2 163 ? -8.73871  -4.01112 27.23674  1.000 33.84285  ? 157 GLY L O   1 
ATOM   2849 N N   . ASN B 2 164 ? -10.16383 -3.16218 28.75338  1.000 25.57297  ? 158 ASN L N   1 
ATOM   2850 C CA  . ASN B 2 164 ? -10.90536 -2.37986 27.77182  1.000 28.40070  ? 158 ASN L CA  1 
ATOM   2851 C C   . ASN B 2 164 ? -10.76776 -0.86862 27.99891  1.000 24.98356  ? 158 ASN L C   1 
ATOM   2852 O O   . ASN B 2 164 ? -11.63722 -0.10240 27.57813  1.000 24.82061  ? 158 ASN L O   1 
ATOM   2853 C CB  . ASN B 2 164 ? -12.38188 -2.78965 27.76123  1.000 26.02772  ? 158 ASN L CB  1 
ATOM   2854 C CG  . ASN B 2 164 ? -13.00881 -2.78769 29.15280  1.000 29.69936  ? 158 ASN L CG  1 
ATOM   2855 O OD1 . ASN B 2 164 ? -12.36733 -2.42681 30.14309  1.000 28.40325  ? 158 ASN L OD1 1 
ATOM   2856 N ND2 . ASN B 2 164 ? -14.27344 -3.19570 29.23157  1.000 26.35380  ? 158 ASN L ND2 1 
ATOM   2857 N N   . SER B 2 165 ? -9.67057  -0.40983 28.61841  1.000 22.78569  ? 159 SER L N   1 
ATOM   2858 C CA  . SER B 2 165 ? -9.46940  1.02498  28.82181  1.000 21.90632  ? 159 SER L CA  1 
ATOM   2859 C C   . SER B 2 165 ? -8.01180  1.41735  28.60317  1.000 23.27174  ? 159 SER L C   1 
ATOM   2860 O O   . SER B 2 165 ? -7.09773  0.60496  28.74352  1.000 22.45772  ? 159 SER L O   1 
ATOM   2861 C CB  . SER B 2 165 ? -9.92892  1.47186  30.22124  1.000 20.15491  ? 159 SER L CB  1 
ATOM   2862 O OG  . SER B 2 165 ? -9.16185  0.85515  31.23949  1.000 22.48257  ? 159 SER L OG  1 
ATOM   2863 N N   . GLN B 2 166 ? -7.80850  2.68446  28.24663  1.000 21.95524  ? 160 GLN L N   1 
ATOM   2864 C CA  . GLN B 2 166 ? -6.48814  3.26004  28.04201  1.000 18.82243  ? 160 GLN L CA  1 
ATOM   2865 C C   . GLN B 2 166 ? -6.39998  4.60718  28.74642  1.000 23.78638  ? 160 GLN L C   1 
ATOM   2866 O O   . GLN B 2 166 ? -7.36455  5.37905  28.74502  1.000 19.87593  ? 160 GLN L O   1 
ATOM   2867 C CB  . GLN B 2 166 ? -6.18186  3.44912  26.54099  1.000 21.82104  ? 160 GLN L CB  1 
ATOM   2868 C CG  . GLN B 2 166 ? -5.77685  2.16292  25.83535  1.000 25.99894  ? 160 GLN L CG  1 
ATOM   2869 C CD  . GLN B 2 166 ? -5.33648  2.40540  24.40794  1.000 27.21005  ? 160 GLN L CD  1 
ATOM   2870 O OE1 . GLN B 2 166 ? -6.13657  2.78891  23.56486  1.000 29.65572  ? 160 GLN L OE1 1 
ATOM   2871 N NE2 . GLN B 2 166 ? -4.04956  2.19694  24.13514  1.000 28.32170  ? 160 GLN L NE2 1 
ATOM   2872 N N   . GLU B 2 167 ? -5.22620  4.90463  29.29507  1.000 17.58386  ? 161 GLU L N   1 
ATOM   2873 C CA  . GLU B 2 167 ? -4.97014  6.15626  29.99743  1.000 19.74337  ? 161 GLU L CA  1 
ATOM   2874 C C   . GLU B 2 167 ? -4.00907  7.03434  29.22208  1.000 18.25526  ? 161 GLU L C   1 
ATOM   2875 O O   . GLU B 2 167 ? -3.12204  6.54538  28.52200  1.000 19.36817  ? 161 GLU L O   1 
ATOM   2876 C CB  . GLU B 2 167 ? -4.36436  5.92174  31.38663  1.000 20.95717  ? 161 GLU L CB  1 
ATOM   2877 C CG  . GLU B 2 167 ? -5.34476  5.40979  32.36795  1.000 23.73044  ? 161 GLU L CG  1 
ATOM   2878 C CD  . GLU B 2 167 ? -4.74449  5.27038  33.75200  1.000 35.59044  ? 161 GLU L CD  1 
ATOM   2879 O OE1 . GLU B 2 167 ? -3.57643  5.68474  33.93767  1.000 28.38278  ? 161 GLU L OE1 1 
ATOM   2880 O OE2 . GLU B 2 167 ? -5.45189  4.75225  34.64404  1.000 28.70861  ? 161 GLU L OE2 1 
ATOM   2881 N N   . SER B 2 168 ? -4.18257  8.34320  29.38227  1.000 19.91864  ? 162 SER L N   1 
ATOM   2882 C CA  . SER B 2 168 ? -3.23861  9.33268  28.89093  1.000 17.27451  ? 162 SER L CA  1 
ATOM   2883 C C   . SER B 2 168 ? -3.06699  10.39153 29.97403  1.000 20.15288  ? 162 SER L C   1 
ATOM   2884 O O   . SER B 2 168 ? -4.03994  10.78090 30.62066  1.000 17.93809  ? 162 SER L O   1 
ATOM   2885 C CB  . SER B 2 168 ? -3.72529  9.96240  27.58231  1.000 19.89363  ? 162 SER L CB  1 
ATOM   2886 O OG  . SER B 2 168 ? -2.72495  10.82213 27.05455  1.000 20.22538  ? 162 SER L OG  1 
ATOM   2887 N N   . VAL B 2 169 ? -1.83068  10.82859 30.19636  1.000 18.78158  ? 163 VAL L N   1 
ATOM   2888 C CA  . VAL B 2 169 ? -1.52214  11.81051 31.23164  1.000 22.04315  ? 163 VAL L CA  1 
ATOM   2889 C C   . VAL B 2 169 ? -0.79923  12.98511 30.59456  1.000 21.55744  ? 163 VAL L C   1 
ATOM   2890 O O   . VAL B 2 169 ? 0.07755   12.79116 29.74336  1.000 21.16254  ? 163 VAL L O   1 
ATOM   2891 C CB  . VAL B 2 169 ? -0.65310  11.19539 32.34684  1.000 24.31909  ? 163 VAL L CB  1 
ATOM   2892 C CG1 . VAL B 2 169 ? -0.61422  12.11984 33.55401  1.000 21.40372  ? 163 VAL L CG1 1 
ATOM   2893 C CG2 . VAL B 2 169 ? -1.18908  9.82609  32.73944  1.000 30.99835  ? 163 VAL L CG2 1 
ATOM   2894 N N   . THR B 2 170 ? -1.16113  14.20193 31.00026  1.000 22.20228  ? 164 THR L N   1 
ATOM   2895 C CA  . THR B 2 170 ? -0.40085  15.34907 30.53955  1.000 19.15923  ? 164 THR L CA  1 
ATOM   2896 C C   . THR B 2 170 ? 0.94065   15.41060 31.26148  1.000 22.10874  ? 164 THR L C   1 
ATOM   2897 O O   . THR B 2 170 ? 1.19806   14.69280 32.23033  1.000 28.74714  ? 164 THR L O   1 
ATOM   2898 C CB  . THR B 2 170 ? -1.15038  16.65791 30.77239  1.000 21.56978  ? 164 THR L CB  1 
ATOM   2899 O OG1 . THR B 2 170 ? -1.41854  16.80313 32.17558  1.000 27.68741  ? 164 THR L OG1 1 
ATOM   2900 C CG2 . THR B 2 170 ? -2.44957  16.68308 29.99613  1.000 25.47129  ? 164 THR L CG2 1 
ATOM   2901 N N   . GLU B 2 171 ? 1.81879   16.26141 30.75175  1.000 23.74133  ? 165 GLU L N   1 
ATOM   2902 C CA  . GLU B 2 171 ? 3.00886   16.61882 31.49948  1.000 29.48710  ? 165 GLU L CA  1 
ATOM   2903 C C   . GLU B 2 171 ? 2.64901   17.72424 32.49219  1.000 22.51242  ? 165 GLU L C   1 
ATOM   2904 O O   . GLU B 2 171 ? 1.59897   18.36818 32.38194  1.000 23.34279  ? 165 GLU L O   1 
ATOM   2905 C CB  . GLU B 2 171 ? 4.12330   17.05715 30.54163  1.000 33.00534  ? 165 GLU L CB  1 
ATOM   2906 C CG  . GLU B 2 171 ? 4.40346   16.07819 29.38276  1.000 38.03978  ? 165 GLU L CG  1 
ATOM   2907 C CD  . GLU B 2 171 ? 3.37668   16.15944 28.22677  1.000 57.67020  ? 165 GLU L CD  1 
ATOM   2908 O OE1 . GLU B 2 171 ? 2.29801   16.79515 28.39388  1.000 51.18967  ? 165 GLU L OE1 1 
ATOM   2909 O OE2 . GLU B 2 171 ? 3.64894   15.57818 27.14415  1.000 53.21260  ? 165 GLU L OE2 1 
ATOM   2910 N N   . GLN B 2 172 ? 3.52174   17.93803 33.47289  1.000 22.54213  ? 166 GLN L N   1 
ATOM   2911 C CA  . GLN B 2 172 ? 3.28434   18.96228 34.48757  1.000 24.91445  ? 166 GLN L CA  1 
ATOM   2912 C C   . GLN B 2 172 ? 2.94387   20.30332 33.86128  1.000 27.64645  ? 166 GLN L C   1 
ATOM   2913 O O   . GLN B 2 172 ? 3.64601   20.78079 32.96442  1.000 30.34030  ? 166 GLN L O   1 
ATOM   2914 C CB  . GLN B 2 172 ? 4.51087   19.12325 35.38297  1.000 24.66573  ? 166 GLN L CB  1 
ATOM   2915 C CG  . GLN B 2 172 ? 4.43819   18.33298 36.64469  1.000 39.11466  ? 166 GLN L CG  1 
ATOM   2916 C CD  . GLN B 2 172 ? 5.49569   18.72067 37.65293  1.000 38.23230  ? 166 GLN L CD  1 
ATOM   2917 O OE1 . GLN B 2 172 ? 6.65745   18.33358 37.52838  1.000 39.86018  ? 166 GLN L OE1 1 
ATOM   2918 N NE2 . GLN B 2 172 ? 5.09224   19.47867 38.67160  1.000 27.20504  ? 166 GLN L NE2 1 
ATOM   2919 N N   . ASP B 2 173 ? 1.85951   20.90331 34.34560  1.000 24.63877  ? 167 ASP L N   1 
ATOM   2920 C CA  . ASP B 2 173 ? 1.41205   22.20618 33.86369  1.000 24.24820  ? 167 ASP L CA  1 
ATOM   2921 C C   . ASP B 2 173 ? 2.45683   23.27526 34.17125  1.000 35.36000  ? 167 ASP L C   1 
ATOM   2922 O O   . ASP B 2 173 ? 2.96958   23.35193 35.29092  1.000 26.56054  ? 167 ASP L O   1 
ATOM   2923 C CB  . ASP B 2 173 ? 0.08068   22.55946 34.52462  1.000 22.65747  ? 167 ASP L CB  1 
ATOM   2924 C CG  . ASP B 2 173 ? -0.48134  23.89444 34.06269  1.000 33.36833  ? 167 ASP L CG  1 
ATOM   2925 O OD1 . ASP B 2 173 ? -1.12609  23.92515 32.98544  1.000 35.95822  ? 167 ASP L OD1 1 
ATOM   2926 O OD2 . ASP B 2 173 ? -0.30253  24.90813 34.78942  1.000 30.79357  ? 167 ASP L OD2 1 
ATOM   2927 N N   . SER B 2 174 ? 2.74595   24.12490 33.18068  1.000 28.28948  ? 168 SER L N   1 
ATOM   2928 C CA  . SER B 2 174 ? 3.77161   25.15105 33.33079  1.000 23.55177  ? 168 SER L CA  1 
ATOM   2929 C C   . SER B 2 174 ? 3.38142   26.27284 34.28742  1.000 27.22579  ? 168 SER L C   1 
ATOM   2930 O O   . SER B 2 174 ? 4.24726   27.07183 34.64634  1.000 27.42108  ? 168 SER L O   1 
ATOM   2931 C CB  . SER B 2 174 ? 4.10563   25.75640 31.96881  1.000 23.27187  ? 168 SER L CB  1 
ATOM   2932 O OG  . SER B 2 174 ? 3.01854   26.55097 31.51888  1.000 37.05383  ? 168 SER L OG  1 
ATOM   2933 N N   . LYS B 2 175 ? 2.11946   26.36968 34.70197  1.000 28.37661  ? 169 LYS L N   1 
ATOM   2934 C CA  . LYS B 2 175 ? 1.69731   27.41764 35.62478  1.000 29.04874  ? 169 LYS L CA  1 
ATOM   2935 C C   . LYS B 2 175 ? 1.43574   26.90032 37.03559  1.000 34.78493  ? 169 LYS L C   1 
ATOM   2936 O O   . LYS B 2 175 ? 2.00520   27.43321 37.99372  1.000 26.64573  ? 169 LYS L O   1 
ATOM   2937 C CB  . LYS B 2 175 ? 0.45901   28.14290 35.07492  1.000 29.04858  ? 169 LYS L CB  1 
ATOM   2938 C CG  . LYS B 2 175 ? 0.60595   28.55245 33.59381  1.000 41.13881  ? 169 LYS L CG  1 
ATOM   2939 C CD  . LYS B 2 175 ? 0.22293   30.00809 33.32294  1.000 44.28275  ? 169 LYS L CD  1 
ATOM   2940 C CE  . LYS B 2 175 ? -1.20018  30.30587 33.77607  1.000 58.42495  ? 169 LYS L CE  1 
ATOM   2941 N NZ  . LYS B 2 175 ? -2.19209  29.41954 33.11286  1.000 61.31449  ? 169 LYS L NZ  1 
ATOM   2942 N N   . ASP B 2 176 ? 0.62131   25.84976 37.20886  1.000 31.32814  ? 170 ASP L N   1 
ATOM   2943 C CA  . ASP B 2 176 ? 0.30798   25.36095 38.55041  1.000 21.35871  ? 170 ASP L CA  1 
ATOM   2944 C C   . ASP B 2 176 ? 1.01153   24.05954 38.91679  1.000 28.49747  ? 170 ASP L C   1 
ATOM   2945 O O   . ASP B 2 176 ? 0.83728   23.58197 40.04099  1.000 28.94484  ? 170 ASP L O   1 
ATOM   2946 C CB  . ASP B 2 176 ? -1.22097  25.23599 38.73830  1.000 29.23251  ? 170 ASP L CB  1 
ATOM   2947 C CG  . ASP B 2 176 ? -1.87958  24.17645 37.83064  1.000 36.59537  ? 170 ASP L CG  1 
ATOM   2948 O OD1 . ASP B 2 176 ? -1.19172  23.27226 37.30439  1.000 34.28932  ? 170 ASP L OD1 1 
ATOM   2949 O OD2 . ASP B 2 176 ? -3.11677  24.25313 37.65638  1.000 37.19952  ? 170 ASP L OD2 1 
ATOM   2950 N N   . SER B 2 177 ? 1.81132   23.49168 38.01107  1.000 19.94685  ? 171 SER L N   1 
ATOM   2951 C CA  . SER B 2 177 ? 2.60916   22.27913 38.22362  1.000 23.22248  ? 171 SER L CA  1 
ATOM   2952 C C   . SER B 2 177 ? 1.76271   21.03814 38.52195  1.000 22.77197  ? 171 SER L C   1 
ATOM   2953 O O   . SER B 2 177 ? 2.28737   20.05210 39.04905  1.000 25.08743  ? 171 SER L O   1 
ATOM   2954 C CB  . SER B 2 177 ? 3.65762   22.47901 39.32931  1.000 25.19828  ? 171 SER L CB  1 
ATOM   2955 O OG  . SER B 2 177 ? 4.22536   23.77920 39.24450  1.000 25.93369  ? 171 SER L OG  1 
ATOM   2956 N N   . THR B 2 178 ? 0.47967   21.03769 38.15766  1.000 19.44652  ? 172 THR L N   1 
ATOM   2957 C CA  . THR B 2 178 ? -0.35245  19.85290 38.30443  1.000 23.79090  ? 172 THR L CA  1 
ATOM   2958 C C   . THR B 2 178 ? -0.30057  18.96260 37.06108  1.000 28.43649  ? 172 THR L C   1 
ATOM   2959 O O   . THR B 2 178 ? 0.32508   19.28501 36.04318  1.000 21.24290  ? 172 THR L O   1 
ATOM   2960 C CB  . THR B 2 178 ? -1.79957  20.24413 38.58771  1.000 28.52991  ? 172 THR L CB  1 
ATOM   2961 O OG1 . THR B 2 178 ? -2.27945  21.09396 37.53659  1.000 27.27613  ? 172 THR L OG1 1 
ATOM   2962 C CG2 . THR B 2 178 ? -1.89765  20.97287 39.92703  1.000 25.82432  ? 172 THR L CG2 1 
ATOM   2963 N N   . TYR B 2 179 ? -0.95095  17.80868 37.17359  1.000 22.56766  ? 173 TYR L N   1 
ATOM   2964 C CA  . TYR B 2 179 ? -1.17925  16.89270 36.06576  1.000 23.48171  ? 173 TYR L CA  1 
ATOM   2965 C C   . TYR B 2 179 ? -2.67306  16.78776 35.77942  1.000 23.84835  ? 173 TYR L C   1 
ATOM   2966 O O   . TYR B 2 179 ? -3.51441  17.09830 36.62825  1.000 16.92978  ? 173 TYR L O   1 
ATOM   2967 C CB  . TYR B 2 179 ? -0.62864  15.50121 36.37597  1.000 18.27202  ? 173 TYR L CB  1 
ATOM   2968 C CG  . TYR B 2 179 ? 0.84478   15.45645 36.73982  1.000 29.56217  ? 173 TYR L CG  1 
ATOM   2969 C CD1 . TYR B 2 179 ? 1.25988   15.57945 38.05894  1.000 29.32996  ? 173 TYR L CD1 1 
ATOM   2970 C CD2 . TYR B 2 179 ? 1.81734   15.27006 35.76142  1.000 27.04377  ? 173 TYR L CD2 1 
ATOM   2971 C CE1 . TYR B 2 179 ? 2.60984   15.52608 38.39477  1.000 36.01413  ? 173 TYR L CE1 1 
ATOM   2972 C CE2 . TYR B 2 179 ? 3.15641   15.20547 36.08518  1.000 33.37806  ? 173 TYR L CE2 1 
ATOM   2973 C CZ  . TYR B 2 179 ? 3.54794   15.33431 37.39866  1.000 39.44548  ? 173 TYR L CZ  1 
ATOM   2974 O OH  . TYR B 2 179 ? 4.88350   15.28237 37.70544  1.000 47.17829  ? 173 TYR L OH  1 
ATOM   2975 N N   . SER B 2 180 ? -3.00811  16.34481 34.56354  1.000 19.13490  ? 174 SER L N   1 
ATOM   2976 C CA  . SER B 2 180 ? -4.36518  15.90406 34.28443  1.000 16.53135  ? 174 SER L CA  1 
ATOM   2977 C C   . SER B 2 180 ? -4.29001  14.53383 33.62790  1.000 18.40357  ? 174 SER L C   1 
ATOM   2978 O O   . SER B 2 180 ? -3.26681  14.16639 33.05542  1.000 19.13370  ? 174 SER L O   1 
ATOM   2979 C CB  . SER B 2 180 ? -5.12343  16.90865 33.42022  1.000 18.59393  ? 174 SER L CB  1 
ATOM   2980 O OG  . SER B 2 180 ? -5.19337  18.17897 34.07751  1.000 24.39268  ? 174 SER L OG  1 
ATOM   2981 N N   . LEU B 2 181 ? -5.35663  13.75195 33.76918  1.000 19.69386  ? 175 LEU L N   1 
ATOM   2982 C CA  . LEU B 2 181 ? -5.36439  12.38760 33.26561  1.000 18.25614  ? 175 LEU L CA  1 
ATOM   2983 C C   . LEU B 2 181 ? -6.72104  12.09197 32.63873  1.000 19.88405  ? 175 LEU L C   1 
ATOM   2984 O O   . LEU B 2 181 ? -7.76502  12.49210 33.16333  1.000 18.35068  ? 175 LEU L O   1 
ATOM   2985 C CB  . LEU B 2 181 ? -5.03313  11.38414 34.39650  1.000 17.83974  ? 175 LEU L CB  1 
ATOM   2986 C CG  . LEU B 2 181 ? -4.97358  9.87279  34.10357  1.000 17.98139  ? 175 LEU L CG  1 
ATOM   2987 C CD1 . LEU B 2 181 ? -4.06152  9.13139  35.08327  1.000 22.98793  ? 175 LEU L CD1 1 
ATOM   2988 C CD2 . LEU B 2 181 ? -6.37500  9.24846  34.14241  1.000 21.07508  ? 175 LEU L CD2 1 
ATOM   2989 N N   . SER B 2 182 ? -6.70784  11.38337 31.51676  1.000 18.36329  ? 176 SER L N   1 
ATOM   2990 C CA  . SER B 2 182 ? -7.93058  10.82320 30.97372  1.000 14.05636  ? 176 SER L CA  1 
ATOM   2991 C C   . SER B 2 182 ? -7.82125  9.31195  30.98978  1.000 18.27169  ? 176 SER L C   1 
ATOM   2992 O O   . SER B 2 182 ? -6.73721  8.75256  30.80318  1.000 19.34233  ? 176 SER L O   1 
ATOM   2993 C CB  . SER B 2 182 ? -8.21136  11.30898 29.54380  1.000 15.91550  ? 176 SER L CB  1 
ATOM   2994 O OG  . SER B 2 182 ? -7.17495  10.90435 28.65156  1.000 21.49094  ? 176 SER L OG  1 
ATOM   2995 N N   . SER B 2 183 ? -8.94592  8.65631  31.24716  1.000 17.51341  ? 177 SER L N   1 
ATOM   2996 C CA  . SER B 2 183 ? -9.07157  7.22278  31.06873  1.000 19.23660  ? 177 SER L CA  1 
ATOM   2997 C C   . SER B 2 183 ? -10.27169 6.99160  30.16482  1.000 19.99116  ? 177 SER L C   1 
ATOM   2998 O O   . SER B 2 183 ? -11.33896 7.56273  30.39767  1.000 22.02605  ? 177 SER L O   1 
ATOM   2999 C CB  . SER B 2 183 ? -9.24339  6.51863  32.41991  1.000 18.88443  ? 177 SER L CB  1 
ATOM   3000 O OG  . SER B 2 183 ? -9.26282  5.12388  32.24923  1.000 19.45366  ? 177 SER L OG  1 
ATOM   3001 N N   . THR B 2 184 ? -10.09680 6.19153  29.12089  1.000 17.40531  ? 178 THR L N   1 
ATOM   3002 C CA  . THR B 2 184 ? -11.13123 5.99142  28.11729  1.000 22.12289  ? 178 THR L CA  1 
ATOM   3003 C C   . THR B 2 184 ? -11.52676 4.52396  28.08414  1.000 22.48422  ? 178 THR L C   1 
ATOM   3004 O O   . THR B 2 184 ? -10.70601 3.66244  27.75187  1.000 21.78602  ? 178 THR L O   1 
ATOM   3005 C CB  . THR B 2 184 ? -10.66915 6.44239  26.73297  1.000 18.51585  ? 178 THR L CB  1 
ATOM   3006 O OG1 . THR B 2 184 ? -10.26496 7.81567  26.79501  1.000 22.26267  ? 178 THR L OG1 1 
ATOM   3007 C CG2 . THR B 2 184 ? -11.82342 6.29908  25.73867  1.000 16.66958  ? 178 THR L CG2 1 
ATOM   3008 N N   . LEU B 2 185 ? -12.78282 4.26228  28.42897  1.000 19.45238  ? 179 LEU L N   1 
ATOM   3009 C CA  . LEU B 2 185 ? -13.40354 2.95088  28.35263  1.000 21.81882  ? 179 LEU L CA  1 
ATOM   3010 C C   . LEU B 2 185 ? -14.05691 2.78702  26.98507  1.000 23.10088  ? 179 LEU L C   1 
ATOM   3011 O O   . LEU B 2 185 ? -14.94960 3.56343  26.62560  1.000 22.38625  ? 179 LEU L O   1 
ATOM   3012 C CB  . LEU B 2 185 ? -14.45702 2.81730  29.44757  1.000 19.74366  ? 179 LEU L CB  1 
ATOM   3013 C CG  . LEU B 2 185 ? -15.20839 1.49070  29.48703  1.000 23.18520  ? 179 LEU L CG  1 
ATOM   3014 C CD1 . LEU B 2 185 ? -14.22682 0.40314  29.87172  1.000 25.24422  ? 179 LEU L CD1 1 
ATOM   3015 C CD2 . LEU B 2 185 ? -16.35111 1.55354  30.48742  1.000 24.49462  ? 179 LEU L CD2 1 
ATOM   3016 N N   . THR B 2 186 ? -13.63650 1.77287  26.23390  1.000 25.12568  ? 180 THR L N   1 
ATOM   3017 C CA  . THR B 2 186 ? -14.12288 1.55020  24.87543  1.000 22.52602  ? 180 THR L CA  1 
ATOM   3018 C C   . THR B 2 186 ? -14.94532 0.26735  24.84376  1.000 26.55481  ? 180 THR L C   1 
ATOM   3019 O O   . THR B 2 186 ? -14.43019 -0.80887 25.15266  1.000 24.78058  ? 180 THR L O   1 
ATOM   3020 C CB  . THR B 2 186 ? -12.95154 1.49102  23.89205  1.000 24.31453  ? 180 THR L CB  1 
ATOM   3021 O OG1 . THR B 2 186 ? -12.27628 2.75229  23.91876  1.000 35.34968  ? 180 THR L OG1 1 
ATOM   3022 C CG2 . THR B 2 186 ? -13.43305 1.22273  22.44574  1.000 30.21087  ? 180 THR L CG2 1 
ATOM   3023 N N   . LEU B 2 187 ? -16.22404 0.38901  24.49037  1.000 27.51244  ? 181 LEU L N   1 
ATOM   3024 C CA  . LEU B 2 187 ? -17.13307 -0.74578 24.39258  1.000 26.06844  ? 181 LEU L CA  1 
ATOM   3025 C C   . LEU B 2 187 ? -17.85146 -0.68214 23.05535  1.000 31.50378  ? 181 LEU L C   1 
ATOM   3026 O O   . LEU B 2 187 ? -17.95035 0.37872  22.43758  1.000 26.91122  ? 181 LEU L O   1 
ATOM   3027 C CB  . LEU B 2 187 ? -18.18411 -0.73970 25.50076  1.000 27.88311  ? 181 LEU L CB  1 
ATOM   3028 C CG  . LEU B 2 187 ? -17.72484 -0.67867 26.94535  1.000 35.22666  ? 181 LEU L CG  1 
ATOM   3029 C CD1 . LEU B 2 187 ? -18.94367 -0.68479 27.86287  1.000 38.06527  ? 181 LEU L CD1 1 
ATOM   3030 C CD2 . LEU B 2 187 ? -16.81337 -1.84994 27.24458  1.000 31.79804  ? 181 LEU L CD2 1 
ATOM   3031 N N   . SER B 2 188 ? -18.38843 -1.81629 22.61748  1.000 34.77960  ? 182 SER L N   1 
ATOM   3032 C CA  . SER B 2 188 ? -19.24401 -1.74198 21.44566  1.000 38.36134  ? 182 SER L CA  1 
ATOM   3033 C C   . SER B 2 188 ? -20.58221 -1.12653 21.84554  1.000 29.03607  ? 182 SER L C   1 
ATOM   3034 O O   . SER B 2 188 ? -20.95976 -1.11090 23.02203  1.000 30.12943  ? 182 SER L O   1 
ATOM   3035 C CB  . SER B 2 188 ? -19.43068 -3.12387 20.80864  1.000 30.20631  ? 182 SER L CB  1 
ATOM   3036 O OG  . SER B 2 188 ? -19.82344 -4.07357 21.78172  1.000 35.71923  ? 182 SER L OG  1 
ATOM   3037 N N   . LYS B 2 189 ? -21.27795 -0.55976 20.85685  1.000 28.63212  ? 183 LYS L N   1 
ATOM   3038 C CA  . LYS B 2 189 ? -22.61569 -0.03387 21.11226  1.000 34.14957  ? 183 LYS L CA  1 
ATOM   3039 C C   . LYS B 2 189 ? -23.49218 -1.08095 21.78105  1.000 38.31260  ? 183 LYS L C   1 
ATOM   3040 O O   . LYS B 2 189 ? -24.21419 -0.78486 22.74232  1.000 32.33175  ? 183 LYS L O   1 
ATOM   3041 C CB  . LYS B 2 189 ? -23.25851 0.43737  19.80664  1.000 41.53236  ? 183 LYS L CB  1 
ATOM   3042 C CG  . LYS B 2 189 ? -24.70382 0.91548  19.97072  1.000 46.66584  ? 183 LYS L CG  1 
ATOM   3043 C CD  . LYS B 2 189 ? -25.34876 1.20462  18.62107  1.000 46.34216  ? 183 LYS L CD  1 
ATOM   3044 C CE  . LYS B 2 189 ? -26.69401 1.90172  18.77376  1.000 47.91489  ? 183 LYS L CE  1 
ATOM   3045 N NZ  . LYS B 2 189 ? -27.74951 0.99721  19.30163  1.000 54.80799  ? 183 LYS L NZ  1 
ATOM   3046 N N   . ALA B 2 190 ? -23.42335 -2.32029 21.29418  1.000 41.12718  ? 184 ALA L N   1 
ATOM   3047 C CA  . ALA B 2 190 ? -24.21755 -3.39514 21.87425  1.000 42.27097  ? 184 ALA L CA  1 
ATOM   3048 C C   . ALA B 2 190 ? -23.91354 -3.56482 23.35928  1.000 41.32020  ? 184 ALA L C   1 
ATOM   3049 O O   . ALA B 2 190 ? -24.82916 -3.61706 24.19123  1.000 36.49551  ? 184 ALA L O   1 
ATOM   3050 C CB  . ALA B 2 190 ? -23.96181 -4.69414 21.10808  1.000 49.12025  ? 184 ALA L CB  1 
ATOM   3051 N N   . ASP B 2 191 ? -22.62691 -3.63617 23.71413  1.000 39.91728  ? 185 ASP L N   1 
ATOM   3052 C CA  . ASP B 2 191 ? -22.24978 -3.74827 25.12263  1.000 41.27836  ? 185 ASP L CA  1 
ATOM   3053 C C   . ASP B 2 191 ? -22.75148 -2.55285 25.92540  1.000 36.04832  ? 185 ASP L C   1 
ATOM   3054 O O   . ASP B 2 191 ? -23.37551 -2.71511 26.98348  1.000 40.38876  ? 185 ASP L O   1 
ATOM   3055 C CB  . ASP B 2 191 ? -20.72899 -3.87459 25.25649  1.000 43.64325  ? 185 ASP L CB  1 
ATOM   3056 C CG  . ASP B 2 191 ? -20.18884 -5.18311 24.69977  1.000 55.85970  ? 185 ASP L CG  1 
ATOM   3057 O OD1 . ASP B 2 191 ? -20.98852 -6.02708 24.23344  1.000 48.76960  ? 185 ASP L OD1 1 
ATOM   3058 O OD2 . ASP B 2 191 ? -18.95144 -5.36230 24.72370  1.000 60.59388  ? 185 ASP L OD2 1 
ATOM   3059 N N   . TYR B 2 192 ? -22.48267 -1.33882 25.43176  1.000 33.77089  ? 186 TYR L N   1 
ATOM   3060 C CA  . TYR B 2 192 ? -22.85510 -0.12653 26.15522  1.000 30.46028  ? 186 TYR L CA  1 
ATOM   3061 C C   . TYR B 2 192 ? -24.34336 -0.09946 26.50158  1.000 40.06521  ? 186 TYR L C   1 
ATOM   3062 O O   . TYR B 2 192 ? -24.72008 0.21846  27.63782  1.000 35.95750  ? 186 TYR L O   1 
ATOM   3063 C CB  . TYR B 2 192 ? -22.48168 1.10824  25.33256  1.000 25.28524  ? 186 TYR L CB  1 
ATOM   3064 C CG  . TYR B 2 192 ? -22.91681 2.39671  25.98102  1.000 31.15182  ? 186 TYR L CG  1 
ATOM   3065 C CD1 . TYR B 2 192 ? -22.29587 2.85649  27.14425  1.000 28.48762  ? 186 TYR L CD1 1 
ATOM   3066 C CD2 . TYR B 2 192 ? -23.94781 3.15577  25.43917  1.000 28.27746  ? 186 TYR L CD2 1 
ATOM   3067 C CE1 . TYR B 2 192 ? -22.70053 4.03525  27.74661  1.000 26.90039  ? 186 TYR L CE1 1 
ATOM   3068 C CE2 . TYR B 2 192 ? -24.35911 4.33640  26.03237  1.000 24.68413  ? 186 TYR L CE2 1 
ATOM   3069 C CZ  . TYR B 2 192 ? -23.73023 4.76456  27.19241  1.000 31.98782  ? 186 TYR L CZ  1 
ATOM   3070 O OH  . TYR B 2 192 ? -24.13260 5.92578  27.79111  1.000 25.85334  ? 186 TYR L OH  1 
ATOM   3071 N N   . GLU B 2 193 ? -25.20750 -0.42187 25.54026  1.000 34.31947  ? 187 GLU L N   1 
ATOM   3072 C CA  . GLU B 2 193 ? -26.64504 -0.36661 25.78351  1.000 40.92743  ? 187 GLU L CA  1 
ATOM   3073 C C   . GLU B 2 193 ? -27.18022 -1.52327 26.62984  1.000 38.24485  ? 187 GLU L C   1 
ATOM   3074 O O   . GLU B 2 193 ? -28.36825 -1.50723 26.97158  1.000 39.31934  ? 187 GLU L O   1 
ATOM   3075 C CB  . GLU B 2 193 ? -27.38990 -0.30096 24.44850  1.000 37.55191  ? 187 GLU L CB  1 
ATOM   3076 C CG  . GLU B 2 193 ? -27.34207 1.08443  23.83734  1.000 39.03656  ? 187 GLU L CG  1 
ATOM   3077 C CD  . GLU B 2 193 ? -27.82076 1.12689  22.40102  1.000 57.38128  ? 187 GLU L CD  1 
ATOM   3078 O OE1 . GLU B 2 193 ? -28.11616 0.05244  21.82572  1.000 54.24213  ? 187 GLU L OE1 1 
ATOM   3079 O OE2 . GLU B 2 193 ? -27.89299 2.24601  21.84181  1.000 61.09646  ? 187 GLU L OE2 1 
ATOM   3080 N N   . LYS B 2 194 ? -26.35261 -2.50366 26.99637  1.000 35.51103  ? 188 LYS L N   1 
ATOM   3081 C CA  . LYS B 2 194 ? -26.77010 -3.58445 27.88869  1.000 41.89275  ? 188 LYS L CA  1 
ATOM   3082 C C   . LYS B 2 194 ? -26.60624 -3.25849 29.37074  1.000 41.86578  ? 188 LYS L C   1 
ATOM   3083 O O   . LYS B 2 194 ? -26.92894 -4.10545 30.21141  1.000 43.07659  ? 188 LYS L O   1 
ATOM   3084 C CB  . LYS B 2 194 ? -25.98198 -4.87224 27.60327  1.000 40.27192  ? 188 LYS L CB  1 
ATOM   3085 C CG  . LYS B 2 194 ? -26.30760 -5.57469 26.29561  1.000 55.27102  ? 188 LYS L CG  1 
ATOM   3086 C CD  . LYS B 2 194 ? -25.43103 -6.82183 26.10311  1.000 49.54183  ? 188 LYS L CD  1 
ATOM   3087 C CE  . LYS B 2 194 ? -25.21321 -7.12039 24.61765  1.000 62.58275  ? 188 LYS L CE  1 
ATOM   3088 N NZ  . LYS B 2 194 ? -24.30340 -8.27882 24.37030  1.000 54.43044  ? 188 LYS L NZ  1 
ATOM   3089 N N   . HIS B 2 195 ? -26.09949 -2.08269 29.72974  1.000 40.01706  ? 189 HIS L N   1 
ATOM   3090 C CA  . HIS B 2 195 ? -25.85439 -1.79204 31.13670  1.000 36.09103  ? 189 HIS L CA  1 
ATOM   3091 C C   . HIS B 2 195 ? -26.34100 -0.39019 31.46674  1.000 33.36990  ? 189 HIS L C   1 
ATOM   3092 O O   . HIS B 2 195 ? -26.56789 0.43480  30.57565  1.000 33.22586  ? 189 HIS L O   1 
ATOM   3093 C CB  . HIS B 2 195 ? -24.37127 -1.94938 31.48222  1.000 37.38462  ? 189 HIS L CB  1 
ATOM   3094 C CG  . HIS B 2 195 ? -23.82074 -3.30349 31.15844  1.000 38.67559  ? 189 HIS L CG  1 
ATOM   3095 N ND1 . HIS B 2 195 ? -23.14615 -3.57324 29.98664  1.000 46.39021  ? 189 HIS L ND1 1 
ATOM   3096 C CD2 . HIS B 2 195 ? -23.86354 -4.46969 31.84410  1.000 35.71941  ? 189 HIS L CD2 1 
ATOM   3097 C CE1 . HIS B 2 195 ? -22.78902 -4.84482 29.96869  1.000 37.41286  ? 189 HIS L CE1 1 
ATOM   3098 N NE2 . HIS B 2 195 ? -23.21375 -5.41115 31.08308  1.000 48.22080  ? 189 HIS L NE2 1 
ATOM   3099 N N   . LYS B 2 196 ? -26.49375 -0.12304 32.76674  1.000 29.22683  ? 190 LYS L N   1 
ATOM   3100 C CA  . LYS B 2 196 ? -27.01985 1.15861  33.22463  1.000 35.63226  ? 190 LYS L CA  1 
ATOM   3101 C C   . LYS B 2 196 ? -25.98324 2.04620  33.89706  1.000 31.93075  ? 190 LYS L C   1 
ATOM   3102 O O   . LYS B 2 196 ? -25.88980 3.23384  33.57211  1.000 33.17805  ? 190 LYS L O   1 
ATOM   3103 C CB  . LYS B 2 196 ? -28.19946 0.94831  34.18969  1.000 33.94828  ? 190 LYS L CB  1 
ATOM   3104 C CG  . LYS B 2 196 ? -28.98317 2.23599  34.46823  1.000 43.51594  ? 190 LYS L CG  1 
ATOM   3105 C CD  . LYS B 2 196 ? -30.10918 2.02765  35.47971  1.000 53.32922  ? 190 LYS L CD  1 
ATOM   3106 C CE  . LYS B 2 196 ? -30.91596 3.30644  35.68471  1.000 53.35173  ? 190 LYS L CE  1 
ATOM   3107 N NZ  . LYS B 2 196 ? -31.92261 3.18469  36.78063  1.000 53.78254  ? 190 LYS L NZ  1 
ATOM   3108 N N   . VAL B 2 197 ? -25.21624 1.52149  34.84722  1.000 31.09020  ? 191 VAL L N   1 
ATOM   3109 C CA  . VAL B 2 197 ? -24.38480 2.34958  35.71839  1.000 32.54590  ? 191 VAL L CA  1 
ATOM   3110 C C   . VAL B 2 197 ? -22.94432 2.29680  35.23560  1.000 26.23847  ? 191 VAL L C   1 
ATOM   3111 O O   . VAL B 2 197 ? -22.32494 1.22848  35.17953  1.000 28.05356  ? 191 VAL L O   1 
ATOM   3112 C CB  . VAL B 2 197 ? -24.48111 1.91329  37.18839  1.000 29.05014  ? 191 VAL L CB  1 
ATOM   3113 C CG1 . VAL B 2 197 ? -23.63537 2.83186  38.05617  1.000 23.01338  ? 191 VAL L CG1 1 
ATOM   3114 C CG2 . VAL B 2 197 ? -25.93799 1.93271  37.64838  1.000 36.98570  ? 191 VAL L CG2 1 
ATOM   3115 N N   . TYR B 2 198 ? -22.40094 3.45958  34.91871  1.000 26.44350  ? 192 TYR L N   1 
ATOM   3116 C CA  . TYR B 2 198 ? -21.02352 3.58368  34.47567  1.000 18.55863  ? 192 TYR L CA  1 
ATOM   3117 C C   . TYR B 2 198 ? -20.30797 4.42408  35.51197  1.000 26.04870  ? 192 TYR L C   1 
ATOM   3118 O O   . TYR B 2 198 ? -20.76602 5.52397  35.83560  1.000 23.16237  ? 192 TYR L O   1 
ATOM   3119 C CB  . TYR B 2 198 ? -20.96561 4.20568  33.08125  1.000 20.50655  ? 192 TYR L CB  1 
ATOM   3120 C CG  . TYR B 2 198 ? -21.44084 3.21471  32.04514  1.000 23.87398  ? 192 TYR L CG  1 
ATOM   3121 C CD1 . TYR B 2 198 ? -22.79855 3.06066  31.76397  1.000 27.19552  ? 192 TYR L CD1 1 
ATOM   3122 C CD2 . TYR B 2 198 ? -20.54100 2.38387  31.40083  1.000 26.17846  ? 192 TYR L CD2 1 
ATOM   3123 C CE1 . TYR B 2 198 ? -23.23223 2.13135  30.84105  1.000 24.85314  ? 192 TYR L CE1 1 
ATOM   3124 C CE2 . TYR B 2 198 ? -20.96356 1.45685  30.48064  1.000 27.63986  ? 192 TYR L CE2 1 
ATOM   3125 C CZ  . TYR B 2 198 ? -22.30420 1.33417  30.20505  1.000 30.60427  ? 192 TYR L CZ  1 
ATOM   3126 O OH  . TYR B 2 198 ? -22.69975 0.40512  29.28022  1.000 28.93700  ? 192 TYR L OH  1 
ATOM   3127 N N   . ALA B 2 199 ? -19.21836 3.89995  36.06266  1.000 20.56616  ? 193 ALA L N   1 
ATOM   3128 C CA  . ALA B 2 199 ? -18.53755 4.62538  37.12552  1.000 20.16625  ? 193 ALA L CA  1 
ATOM   3129 C C   . ALA B 2 199 ? -17.02794 4.54499  36.95342  1.000 24.51499  ? 193 ALA L C   1 
ATOM   3130 O O   . ALA B 2 199 ? -16.48210 3.51059  36.56302  1.000 21.05001  ? 193 ALA L O   1 
ATOM   3131 C CB  . ALA B 2 199 ? -18.94483 4.07970  38.50035  1.000 19.72587  ? 193 ALA L CB  1 
ATOM   3132 N N   . CYS B 2 200 ? -16.35469 5.64892  37.23055  1.000 19.18504  ? 194 CYS L N   1 
ATOM   3133 C CA  A CYS B 2 200 ? -14.90413 5.72651  37.24976  0.548 21.29788  ? 194 CYS L CA  1 
ATOM   3134 C CA  B CYS B 2 200 ? -14.90342 5.64632  37.27557  0.452 19.73230  ? 194 CYS L CA  1 
ATOM   3135 C C   . CYS B 2 200 ? -14.46032 6.03921  38.67525  1.000 22.50576  ? 194 CYS L C   1 
ATOM   3136 O O   . CYS B 2 200 ? -14.88382 7.05894  39.23087  1.000 19.65314  ? 194 CYS L O   1 
ATOM   3137 C CB  A CYS B 2 200 ? -14.45329 6.80882  36.27321  0.548 22.92624  ? 194 CYS L CB  1 
ATOM   3138 C CB  B CYS B 2 200 ? -14.25314 6.53819  36.20418  0.452 22.70419  ? 194 CYS L CB  1 
ATOM   3139 S SG  A CYS B 2 200 ? -12.76929 7.31956  36.37851  0.548 23.54018  ? 194 CYS L SG  1 
ATOM   3140 S SG  B CYS B 2 200 ? -14.51759 8.31387  36.27083  0.452 22.89788  ? 194 CYS L SG  1 
ATOM   3141 N N   . GLU B 2 201 ? -13.62303 5.18716  39.25135  1.000 24.16594  ? 195 GLU L N   1 
ATOM   3142 C CA  . GLU B 2 201 ? -13.16440 5.32089  40.62986  1.000 21.35263  ? 195 GLU L CA  1 
ATOM   3143 C C   . GLU B 2 201 ? -11.68975 5.70639  40.64628  1.000 22.98916  ? 195 GLU L C   1 
ATOM   3144 O O   . GLU B 2 201 ? -10.85419 5.03693  40.02827  1.000 23.32114  ? 195 GLU L O   1 
ATOM   3145 C CB  . GLU B 2 201 ? -13.38778 4.01540  41.39399  1.000 23.25387  ? 195 GLU L CB  1 
ATOM   3146 C CG  . GLU B 2 201 ? -12.84012 3.98952  42.83076  1.000 21.56304  ? 195 GLU L CG  1 
ATOM   3147 C CD  . GLU B 2 201 ? -12.76941 2.56609  43.37223  1.000 34.72709  ? 195 GLU L CD  1 
ATOM   3148 O OE1 . GLU B 2 201 ? -11.82268 1.83716  43.01414  1.000 35.94511  ? 195 GLU L OE1 1 
ATOM   3149 O OE2 . GLU B 2 201 ? -13.67750 2.16705  44.12451  1.000 40.95811  ? 195 GLU L OE2 1 
ATOM   3150 N N   . VAL B 2 202 ? -11.37598 6.77781  41.36118  1.000 21.14583  ? 196 VAL L N   1 
ATOM   3151 C CA  . VAL B 2 202 ? -10.03202 7.33298  41.43508  1.000 18.14231  ? 196 VAL L CA  1 
ATOM   3152 C C   . VAL B 2 202 ? -9.54919  7.19207  42.86906  1.000 21.33664  ? 196 VAL L C   1 
ATOM   3153 O O   . VAL B 2 202 ? -10.18401 7.71730  43.79509  1.000 21.30544  ? 196 VAL L O   1 
ATOM   3154 C CB  . VAL B 2 202 ? -10.00538 8.80784  41.00781  1.000 21.49885  ? 196 VAL L CB  1 
ATOM   3155 C CG1 . VAL B 2 202 ? -8.59287  9.35504  41.09612  1.000 23.94575  ? 196 VAL L CG1 1 
ATOM   3156 C CG2 . VAL B 2 202 ? -10.59672 8.96296  39.61398  1.000 21.88093  ? 196 VAL L CG2 1 
ATOM   3157 N N   . THR B 2 203 ? -8.42006  6.51529  43.05078  1.000 22.42810  ? 197 THR L N   1 
ATOM   3158 C CA  . THR B 2 203 ? -7.82004  6.30489  44.36448  1.000 19.79843  ? 197 THR L CA  1 
ATOM   3159 C C   . THR B 2 203 ? -6.44810  6.96295  44.41383  1.000 22.20308  ? 197 THR L C   1 
ATOM   3160 O O   . THR B 2 203 ? -5.61292  6.72458  43.53531  1.000 22.97104  ? 197 THR L O   1 
ATOM   3161 C CB  . THR B 2 203 ? -7.70816  4.80729  44.67330  1.000 19.89469  ? 197 THR L CB  1 
ATOM   3162 O OG1 . THR B 2 203 ? -8.99664  4.20560  44.52574  1.000 30.29913  ? 197 THR L OG1 1 
ATOM   3163 C CG2 . THR B 2 203 ? -7.20181  4.56830  46.11036  1.000 27.19807  ? 197 THR L CG2 1 
ATOM   3164 N N   . GLN B 2 204 ? -6.24325  7.81905  45.42156  1.000 23.30322  ? 198 GLN L N   1 
ATOM   3165 C CA  . GLN B 2 204 ? -4.93533  8.35797  45.79091  1.000 24.74845  ? 198 GLN L CA  1 
ATOM   3166 C C   . GLN B 2 204 ? -4.81986  8.31498  47.30761  1.000 24.22629  ? 198 GLN L C   1 
ATOM   3167 O O   . GLN B 2 204 ? -5.65743  8.89525  48.00602  1.000 22.33550  ? 198 GLN L O   1 
ATOM   3168 C CB  . GLN B 2 204 ? -4.74553  9.79681  45.31209  1.000 27.12701  ? 198 GLN L CB  1 
ATOM   3169 C CG  . GLN B 2 204 ? -4.52578  9.94271  43.82495  1.000 25.05213  ? 198 GLN L CG  1 
ATOM   3170 C CD  . GLN B 2 204 ? -4.09764  11.33889 43.45833  1.000 27.60919  ? 198 GLN L CD  1 
ATOM   3171 O OE1 . GLN B 2 204 ? -4.81781  12.30486 43.71407  1.000 29.01927  ? 198 GLN L OE1 1 
ATOM   3172 N NE2 . GLN B 2 204 ? -2.90929  11.46262 42.85939  1.000 34.14848  ? 198 GLN L NE2 1 
ATOM   3173 N N   . GLY B 2 205 ? -3.79187  7.64773  47.81208  1.000 31.40376  ? 199 GLY L N   1 
ATOM   3174 C CA  . GLY B 2 205 ? -3.62199  7.57446  49.25930  1.000 29.09324  ? 199 GLY L CA  1 
ATOM   3175 C C   . GLY B 2 205 ? -4.81545  6.90599  49.91700  1.000 22.91137  ? 199 GLY L C   1 
ATOM   3176 O O   . GLY B 2 205 ? -5.26682  5.83361  49.50101  1.000 28.68553  ? 199 GLY L O   1 
ATOM   3177 N N   . THR B 2 206 ? -5.37490  7.56907  50.92559  1.000 20.69912  ? 200 THR L N   1 
ATOM   3178 C CA  . THR B 2 206 ? -6.46140  7.00816  51.71260  1.000 25.23332  ? 200 THR L CA  1 
ATOM   3179 C C   . THR B 2 206 ? -7.84903  7.39056  51.19838  1.000 29.25012  ? 200 THR L C   1 
ATOM   3180 O O   . THR B 2 206 ? -8.84085  7.07602  51.86332  1.000 26.58075  ? 200 THR L O   1 
ATOM   3181 C CB  . THR B 2 206 ? -6.29859  7.43817  53.17272  1.000 25.26386  ? 200 THR L CB  1 
ATOM   3182 O OG1 . THR B 2 206 ? -6.00666  8.83816  53.21747  1.000 26.38002  ? 200 THR L OG1 1 
ATOM   3183 C CG2 . THR B 2 206 ? -5.14064  6.68347  53.79653  1.000 29.33343  ? 200 THR L CG2 1 
ATOM   3184 N N   . THR B 2 207 ? -7.94558  8.01815  50.02219  1.000 24.54915  ? 201 THR L N   1 
ATOM   3185 C CA  . THR B 2 207 ? -9.19873  8.54519  49.48978  1.000 22.97016  ? 201 THR L CA  1 
ATOM   3186 C C   . THR B 2 207 ? -9.50359  7.89986  48.14513  1.000 24.32919  ? 201 THR L C   1 
ATOM   3187 O O   . THR B 2 207 ? -8.63181  7.84643  47.27578  1.000 22.08483  ? 201 THR L O   1 
ATOM   3188 C CB  . THR B 2 207 ? -9.12317  10.06415 49.29678  1.000 27.03519  ? 201 THR L CB  1 
ATOM   3189 O OG1 . THR B 2 207 ? -8.89547  10.70121 50.55116  1.000 30.94520  ? 201 THR L OG1 1 
ATOM   3190 C CG2 . THR B 2 207 ? -10.41152 10.61016 48.67573  1.000 24.61887  ? 201 THR L CG2 1 
ATOM   3191 N N   . SER B 2 208 ? -10.73704 7.41907  47.97282  1.000 21.29094  ? 202 SER L N   1 
ATOM   3192 C CA  . SER B 2 208 ? -11.25856 7.06573  46.65600  1.000 24.05408  ? 202 SER L CA  1 
ATOM   3193 C C   . SER B 2 208 ? -12.42273 7.98619  46.33718  1.000 24.29632  ? 202 SER L C   1 
ATOM   3194 O O   . SER B 2 208 ? -13.24489 8.27643  47.21234  1.000 24.50775  ? 202 SER L O   1 
ATOM   3195 C CB  . SER B 2 208 ? -11.72942 5.60949  46.59232  1.000 25.23607  ? 202 SER L CB  1 
ATOM   3196 O OG  . SER B 2 208 ? -10.66685 4.71983  46.86356  1.000 29.06065  ? 202 SER L OG  1 
ATOM   3197 N N   . VAL B 2 209 ? -12.48244 8.46585  45.09649  1.000 19.83742  ? 203 VAL L N   1 
ATOM   3198 C CA  . VAL B 2 209 ? -13.60905 9.25984  44.62268  1.000 19.11822  ? 203 VAL L CA  1 
ATOM   3199 C C   . VAL B 2 209 ? -14.19267 8.53530  43.42091  1.000 19.41814  ? 203 VAL L C   1 
ATOM   3200 O O   . VAL B 2 209 ? -13.45622 8.16756  42.50134  1.000 18.08856  ? 203 VAL L O   1 
ATOM   3201 C CB  . VAL B 2 209 ? -13.19452 10.70025 44.25526  1.000 23.00650  ? 203 VAL L CB  1 
ATOM   3202 C CG1 . VAL B 2 209 ? -14.35483 11.43405 43.57801  1.000 18.20105  ? 203 VAL L CG1 1 
ATOM   3203 C CG2 . VAL B 2 209 ? -12.74695 11.46855 45.48208  1.000 22.47290  ? 203 VAL L CG2 1 
ATOM   3204 N N   . THR B 2 210 ? -15.49945 8.30315  43.43637  1.000 19.04677  ? 204 THR L N   1 
ATOM   3205 C CA  . THR B 2 210 ? -16.18690 7.66456  42.31798  1.000 20.33254  ? 204 THR L CA  1 
ATOM   3206 C C   . THR B 2 210 ? -17.19942 8.62251  41.69702  1.000 22.11826  ? 204 THR L C   1 
ATOM   3207 O O   . THR B 2 210 ? -18.06828 9.16539  42.39233  1.000 20.91102  ? 204 THR L O   1 
ATOM   3208 C CB  . THR B 2 210 ? -16.86099 6.36772  42.77295  1.000 26.20910  ? 204 THR L CB  1 
ATOM   3209 O OG1 . THR B 2 210 ? -15.86057 5.50155  43.32334  1.000 25.76152  ? 204 THR L OG1 1 
ATOM   3210 C CG2 . THR B 2 210 ? -17.54339 5.65535  41.60488  1.000 23.75889  ? 204 THR L CG2 1 
ATOM   3211 N N   . LYS B 2 211 ? -17.09265 8.82205  40.38703  1.000 21.41527  ? 205 LYS L N   1 
ATOM   3212 C CA  . LYS B 2 211 ? -18.06626 9.59876  39.62724  1.000 20.49515  ? 205 LYS L CA  1 
ATOM   3213 C C   . LYS B 2 211 ? -18.80030 8.65072  38.70025  1.000 28.48712  ? 205 LYS L C   1 
ATOM   3214 O O   . LYS B 2 211 ? -18.17149 7.79396  38.06860  1.000 20.22346  ? 205 LYS L O   1 
ATOM   3215 C CB  . LYS B 2 211 ? -17.39679 10.70746 38.81276  1.000 23.65727  ? 205 LYS L CB  1 
ATOM   3216 C CG  . LYS B 2 211 ? -16.90861 11.87844 39.63125  1.000 38.56386  ? 205 LYS L CG  1 
ATOM   3217 C CD  . LYS B 2 211 ? -18.03800 12.84482 39.95227  1.000 31.50310  ? 205 LYS L CD  1 
ATOM   3218 C CE  . LYS B 2 211 ? -18.80599 13.19649 38.70510  1.000 33.84034  ? 205 LYS L CE  1 
ATOM   3219 N NZ  . LYS B 2 211 ? -19.66108 14.41800 38.89680  1.000 51.19083  ? 205 LYS L NZ  1 
ATOM   3220 N N   . SER B 2 212 ? -20.12153 8.78986  38.61300  1.000 23.01258  ? 206 SER L N   1 
ATOM   3221 C CA  . SER B 2 212 ? -20.87006 7.85907  37.78466  1.000 25.45156  ? 206 SER L CA  1 
ATOM   3222 C C   . SER B 2 212 ? -21.96234 8.58069  37.01082  1.000 28.61682  ? 206 SER L C   1 
ATOM   3223 O O   . SER B 2 212 ? -22.23932 9.76590  37.22752  1.000 21.40477  ? 206 SER L O   1 
ATOM   3224 C CB  . SER B 2 212 ? -21.47345 6.72869  38.62770  1.000 26.31266  ? 206 SER L CB  1 
ATOM   3225 O OG  . SER B 2 212 ? -22.30780 7.25863  39.63077  1.000 38.57033  ? 206 SER L OG  1 
ATOM   3226 N N   . PHE B 2 213 ? -22.56785 7.84004  36.08041  1.000 26.34142  ? 207 PHE L N   1 
ATOM   3227 C CA  . PHE B 2 213 ? -23.81021 8.25840  35.44432  1.000 29.48936  ? 207 PHE L CA  1 
ATOM   3228 C C   . PHE B 2 213 ? -24.65448 7.02280  35.17928  1.000 28.79228  ? 207 PHE L C   1 
ATOM   3229 O O   . PHE B 2 213 ? -24.14740 5.89810  35.14295  1.000 25.68599  ? 207 PHE L O   1 
ATOM   3230 C CB  . PHE B 2 213 ? -23.57563 9.04823  34.14557  1.000 23.22631  ? 207 PHE L CB  1 
ATOM   3231 C CG  . PHE B 2 213 ? -22.98198 8.23722  33.01851  1.000 26.84886  ? 207 PHE L CG  1 
ATOM   3232 C CD1 . PHE B 2 213 ? -23.79429 7.49737  32.16535  1.000 25.38842  ? 207 PHE L CD1 1 
ATOM   3233 C CD2 . PHE B 2 213 ? -21.60732 8.26270  32.77537  1.000 26.89384  ? 207 PHE L CD2 1 
ATOM   3234 C CE1 . PHE B 2 213 ? -23.24022 6.75971  31.11477  1.000 23.83047  ? 207 PHE L CE1 1 
ATOM   3235 C CE2 . PHE B 2 213 ? -21.04690 7.53034  31.72824  1.000 21.35874  ? 207 PHE L CE2 1 
ATOM   3236 C CZ  . PHE B 2 213 ? -21.86657 6.78293  30.89322  1.000 18.07402  ? 207 PHE L CZ  1 
ATOM   3237 N N   . ASN B 2 214 ? -25.96030 7.24699  35.01183  1.000 30.80737  ? 208 ASN L N   1 
ATOM   3238 C CA  . ASN B 2 214 ? -26.89834 6.19843  34.63048  1.000 35.35694  ? 208 ASN L CA  1 
ATOM   3239 C C   . ASN B 2 214 ? -27.25412 6.39709  33.16616  1.000 31.66773  ? 208 ASN L C   1 
ATOM   3240 O O   . ASN B 2 214 ? -27.72476 7.47019  32.78539  1.000 37.43635  ? 208 ASN L O   1 
ATOM   3241 C CB  . ASN B 2 214 ? -28.14937 6.23664  35.50585  1.000 42.08943  ? 208 ASN L CB  1 
ATOM   3242 C CG  . ASN B 2 214 ? -27.85849 5.85619  36.93964  1.000 47.87041  ? 208 ASN L CG  1 
ATOM   3243 O OD1 . ASN B 2 214 ? -27.26249 4.81257  37.20598  1.000 44.49535  ? 208 ASN L OD1 1 
ATOM   3244 N ND2 . ASN B 2 214 ? -28.25370 6.71496  37.87353  1.000 57.47242  ? 208 ASN L ND2 1 
ATOM   3245 N N   . ARG B 2 215 ? -27.01572 5.37687  32.35187  1.000 30.54584  ? 209 ARG L N   1 
ATOM   3246 C CA  . ARG B 2 215 ? -27.10649 5.54635  30.90779  1.000 38.13779  ? 209 ARG L CA  1 
ATOM   3247 C C   . ARG B 2 215 ? -28.49764 6.01958  30.51784  1.000 46.55532  ? 209 ARG L C   1 
ATOM   3248 O O   . ARG B 2 215 ? -29.49037 5.32888  30.76523  1.000 47.63375  ? 209 ARG L O   1 
ATOM   3249 C CB  . ARG B 2 215 ? -26.76442 4.24306  30.18536  1.000 30.96680  ? 209 ARG L CB  1 
ATOM   3250 C CG  . ARG B 2 215 ? -26.99403 4.34027  28.68973  1.000 34.83305  ? 209 ARG L CG  1 
ATOM   3251 C CD  . ARG B 2 215 ? -26.81302 3.01112  27.99559  1.000 34.71714  ? 209 ARG L CD  1 
ATOM   3252 N NE  . ARG B 2 215 ? -27.57116 1.93868  28.62968  1.000 40.01578  ? 209 ARG L NE  1 
ATOM   3253 C CZ  . ARG B 2 215 ? -28.79468 1.57406  28.27433  1.000 46.84351  ? 209 ARG L CZ  1 
ATOM   3254 N NH1 . ARG B 2 215 ? -29.43997 2.18312  27.29097  1.000 45.58767  ? 209 ARG L NH1 1 
ATOM   3255 N NH2 . ARG B 2 215 ? -29.38617 0.57338  28.92215  1.000 55.78014  ? 209 ARG L NH2 1 
ATOM   3256 N N   . GLY B 2 216 ? -28.56240 7.21752  29.93811  1.000 51.54767  ? 210 GLY L N   1 
ATOM   3257 C CA  . GLY B 2 216 ? -29.81224 7.78793  29.48414  1.000 56.15778  ? 210 GLY L CA  1 
ATOM   3258 C C   . GLY B 2 216 ? -30.65948 8.36957  30.59451  1.000 63.60853  ? 210 GLY L C   1 
ATOM   3259 O O   . GLY B 2 216 ? -31.77785 7.90466  30.82967  1.000 69.55194  ? 210 GLY L O   1 
ATOM   3260 N N   . GLU B 2 217 ? -30.14177 9.39619  31.29092  1.000 69.79113  ? 211 GLU L N   1 
ATOM   3261 C CA  . GLU B 2 217 ? -30.90059 10.09236 32.33739  1.000 73.18207  ? 211 GLU L CA  1 
ATOM   3262 C C   . GLU B 2 217 ? -30.58196 11.59166 32.26515  1.000 81.10260  ? 211 GLU L C   1 
ATOM   3263 O O   . GLU B 2 217 ? -29.73010 12.10083 32.99681  1.000 85.74442  ? 211 GLU L O   1 
ATOM   3264 C CB  . GLU B 2 217 ? -30.60526 9.51257  33.72185  1.000 59.35606  ? 211 GLU L CB  1 
ATOM   3265 C CG  . GLU B 2 217 ? -31.20098 8.12474  33.95529  1.000 52.12312  ? 211 GLU L CG  1 
ATOM   3266 C CD  . GLU B 2 217 ? -31.23054 7.72466  35.42412  1.000 66.63593  ? 211 GLU L CD  1 
ATOM   3267 O OE1 . GLU B 2 217 ? -30.99782 8.59629  36.29383  1.000 62.85780  ? 211 GLU L OE1 1 
ATOM   3268 O OE2 . GLU B 2 217 ? -31.48645 6.53238  35.70846  1.000 60.63676  ? 211 GLU L OE2 1 
ATOM   3269 N N   . CYS B 2 218 ? -31.28357 12.29478 31.37332  1.000 90.68333  ? 212 CYS L N   1 
ATOM   3270 C CA  . CYS B 2 218 ? -31.18290 13.75337 31.24511  1.000 95.16222  ? 212 CYS L CA  1 
ATOM   3271 C C   . CYS B 2 218 ? -32.27533 14.30855 30.32789  1.000 98.67165  ? 212 CYS L C   1 
ATOM   3272 O O   . CYS B 2 218 ? -32.40263 15.52558 30.15395  1.000 91.94075  ? 212 CYS L O   1 
ATOM   3273 C CB  . CYS B 2 218 ? -29.80415 14.16844 30.71696  1.000 95.63770  ? 212 CYS L CB  1 
ATOM   3274 S SG  . CYS B 2 218 ? -28.75608 15.02951 31.92953  1.000 99.91407  ? 212 CYS L SG  1 
ATOM   3275 N N   . VAL C 1 2   ? -5.45222  69.57169 26.66251  1.000 66.36383  ? 2   VAL A N   1 
ATOM   3276 C CA  . VAL C 1 2   ? -5.81735  68.17613 26.87585  1.000 65.53813  ? 2   VAL A CA  1 
ATOM   3277 C C   . VAL C 1 2   ? -4.60167  67.28002 26.62823  1.000 68.99662  ? 2   VAL A C   1 
ATOM   3278 O O   . VAL C 1 2   ? -4.10498  67.16214 25.50438  1.000 61.94855  ? 2   VAL A O   1 
ATOM   3279 C CB  . VAL C 1 2   ? -7.01438  67.77934 25.99047  1.000 61.80065  ? 2   VAL A CB  1 
ATOM   3280 C CG1 . VAL C 1 2   ? -6.89541  68.41971 24.61203  1.000 62.88898  ? 2   VAL A CG1 1 
ATOM   3281 C CG2 . VAL C 1 2   ? -7.12745  66.26838 25.88186  1.000 56.17272  ? 2   VAL A CG2 1 
ATOM   3282 N N   . GLN C 1 3   ? -4.11913  66.65430 27.69455  1.000 65.03867  ? 3   GLN A N   1 
ATOM   3283 C CA  . GLN C 1 3   ? -2.87718  65.90098 27.66814  1.000 64.34255  ? 3   GLN A CA  1 
ATOM   3284 C C   . GLN C 1 3   ? -3.10067  64.46789 28.13195  1.000 67.78486  ? 3   GLN A C   1 
ATOM   3285 O O   . GLN C 1 3   ? -4.15636  64.10533 28.66030  1.000 64.30474  ? 3   GLN A O   1 
ATOM   3286 C CB  . GLN C 1 3   ? -1.81091  66.56225 28.54854  1.000 70.48223  ? 3   GLN A CB  1 
ATOM   3287 C CG  . GLN C 1 3   ? -1.08671  67.71949 27.90185  1.000 76.08648  ? 3   GLN A CG  1 
ATOM   3288 C CD  . GLN C 1 3   ? 0.36655   67.78977 28.33189  1.000 87.08541  ? 3   GLN A CD  1 
ATOM   3289 O OE1 . GLN C 1 3   ? 0.77481   67.13026 29.28960  1.000 92.16179  ? 3   GLN A OE1 1 
ATOM   3290 N NE2 . GLN C 1 3   ? 1.15925   68.58067 27.61681  1.000 90.53878  ? 3   GLN A NE2 1 
ATOM   3291 N N   . LEU C 1 4   ? -2.05851  63.65876 27.94523  1.000 60.95486  ? 4   LEU A N   1 
ATOM   3292 C CA  . LEU C 1 4   ? -2.10476  62.24459 28.31162  1.000 60.22999  ? 4   LEU A CA  1 
ATOM   3293 C C   . LEU C 1 4   ? -0.64849  61.77348 28.38075  1.000 58.45761  ? 4   LEU A C   1 
ATOM   3294 O O   . LEU C 1 4   ? -0.05895  61.41542 27.36117  1.000 58.73045  ? 4   LEU A O   1 
ATOM   3295 C CB  . LEU C 1 4   ? -2.91151  61.44277 27.31388  1.000 59.47272  ? 4   LEU A CB  1 
ATOM   3296 C CG  . LEU C 1 4   ? -3.27886  60.01901 27.70233  1.000 61.42731  ? 4   LEU A CG  1 
ATOM   3297 C CD1 . LEU C 1 4   ? -3.89942  59.99042 29.09792  1.000 55.61326  ? 4   LEU A CD1 1 
ATOM   3298 C CD2 . LEU C 1 4   ? -4.22802  59.43639 26.65515  1.000 49.90375  ? 4   LEU A CD2 1 
ATOM   3299 N N   . VAL C 1 5   ? -0.08203  61.79836 29.58859  1.000 60.23431  ? 5   VAL A N   1 
ATOM   3300 C CA  . VAL C 1 5   ? 1.34385   61.56577 29.79163  1.000 59.25593  ? 5   VAL A CA  1 
ATOM   3301 C C   . VAL C 1 5   ? 1.55550   60.15136 30.31045  1.000 63.71561  ? 5   VAL A C   1 
ATOM   3302 O O   . VAL C 1 5   ? 0.82464   59.67275 31.18901  1.000 52.97961  ? 5   VAL A O   1 
ATOM   3303 C CB  . VAL C 1 5   ? 1.95288   62.61230 30.74387  1.000 54.27297  ? 5   VAL A CB  1 
ATOM   3304 C CG1 . VAL C 1 5   ? 1.27758   62.56875 32.10242  1.000 64.38828  ? 5   VAL A CG1 1 
ATOM   3305 C CG2 . VAL C 1 5   ? 3.45508   62.40377 30.86740  1.000 58.30288  ? 5   VAL A CG2 1 
ATOM   3306 N N   . GLU C 1 6   ? 2.56605   59.48369 29.76617  1.000 59.74290  ? 6   GLU A N   1 
ATOM   3307 C CA  . GLU C 1 6   ? 2.78767   58.06232 29.96913  1.000 52.20817  ? 6   GLU A CA  1 
ATOM   3308 C C   . GLU C 1 6   ? 3.94342   57.83635 30.93448  1.000 51.03185  ? 6   GLU A C   1 
ATOM   3309 O O   . GLU C 1 6   ? 4.92726   58.58125 30.91957  1.000 55.27628  ? 6   GLU A O   1 
ATOM   3310 C CB  . GLU C 1 6   ? 3.08142   57.39326 28.63392  1.000 54.88829  ? 6   GLU A CB  1 
ATOM   3311 C CG  . GLU C 1 6   ? 2.53569   56.01006 28.51054  1.000 48.44540  ? 6   GLU A CG  1 
ATOM   3312 C CD  . GLU C 1 6   ? 2.12059   55.69661 27.09202  1.000 55.30304  ? 6   GLU A CD  1 
ATOM   3313 O OE1 . GLU C 1 6   ? 1.81151   56.64617 26.32768  1.000 48.95022  ? 6   GLU A OE1 1 
ATOM   3314 O OE2 . GLU C 1 6   ? 2.11326   54.49607 26.74249  1.000 54.88901  ? 6   GLU A OE2 1 
ATOM   3315 N N   . SER C 1 7   ? 3.83137   56.79683 31.76340  1.000 39.58363  ? 7   SER A N   1 
ATOM   3316 C CA  . SER C 1 7   ? 4.82187   56.54196 32.80013  1.000 51.10345  ? 7   SER A CA  1 
ATOM   3317 C C   . SER C 1 7   ? 5.07225   55.05006 32.92836  1.000 43.62606  ? 7   SER A C   1 
ATOM   3318 O O   . SER C 1 7   ? 4.25983   54.21473 32.52319  1.000 43.26183  ? 7   SER A O   1 
ATOM   3319 C CB  . SER C 1 7   ? 4.38603   57.09930 34.15845  1.000 41.69835  ? 7   SER A CB  1 
ATOM   3320 O OG  . SER C 1 7   ? 3.24969   56.39984 34.62701  1.000 49.20007  ? 7   SER A OG  1 
ATOM   3321 N N   . GLY C 1 8   ? 6.19288   54.72945 33.54796  1.000 38.45293  ? 8   GLY A N   1 
ATOM   3322 C CA  . GLY C 1 8   ? 6.62464   53.36355 33.65814  1.000 33.45376  ? 8   GLY A CA  1 
ATOM   3323 C C   . GLY C 1 8   ? 7.47647   52.99779 32.46679  1.000 48.10803  ? 8   GLY A C   1 
ATOM   3324 O O   . GLY C 1 8   ? 7.83330   53.82942 31.62457  1.000 54.70334  ? 8   GLY A O   1 
ATOM   3325 N N   . GLY C 1 9   ? 7.81205   51.72436 32.39215  1.000 38.66718  ? 9   GLY A N   1 
ATOM   3326 C CA  . GLY C 1 9   ? 8.57514   51.24359 31.26522  1.000 49.46319  ? 9   GLY A CA  1 
ATOM   3327 C C   . GLY C 1 9   ? 10.05761  51.49175 31.43862  1.000 47.32618  ? 9   GLY A C   1 
ATOM   3328 O O   . GLY C 1 9   ? 10.51633  52.21338 32.32492  1.000 37.62598  ? 9   GLY A O   1 
ATOM   3329 N N   . GLY C 1 10  ? 10.81949  50.88993 30.54513  1.000 36.90964  ? 10  GLY A N   1 
ATOM   3330 C CA  . GLY C 1 10  ? 12.21357  50.65659 30.81921  1.000 37.80546  ? 10  GLY A CA  1 
ATOM   3331 C C   . GLY C 1 10  ? 12.51197  49.19913 30.56427  1.000 29.21612  ? 10  GLY A C   1 
ATOM   3332 O O   . GLY C 1 10  ? 11.88685  48.58597 29.69793  1.000 39.19565  ? 10  GLY A O   1 
ATOM   3333 N N   . LEU C 1 11  ? 13.44607  48.63230 31.31252  1.000 32.35722  ? 11  LEU A N   1 
ATOM   3334 C CA  . LEU C 1 11  ? 14.00180  47.31920 31.01940  1.000 36.61372  ? 11  LEU A CA  1 
ATOM   3335 C C   . LEU C 1 11  ? 13.37532  46.27585 31.93883  1.000 38.80897  ? 11  LEU A C   1 
ATOM   3336 O O   . LEU C 1 11  ? 13.25895  46.50228 33.14714  1.000 38.42536  ? 11  LEU A O   1 
ATOM   3337 C CB  . LEU C 1 11  ? 15.52414  47.35283 31.17730  1.000 27.55411  ? 11  LEU A CB  1 
ATOM   3338 C CG  . LEU C 1 11  ? 16.31137  46.04798 31.09624  1.000 34.38955  ? 11  LEU A CG  1 
ATOM   3339 C CD1 . LEU C 1 11  ? 16.11845  45.35518 29.73989  1.000 27.79303  ? 11  LEU A CD1 1 
ATOM   3340 C CD2 . LEU C 1 11  ? 17.79548  46.29536 31.38672  1.000 32.71036  ? 11  LEU A CD2 1 
ATOM   3341 N N   . VAL C 1 12  ? 12.95732  45.14239 31.36095  1.000 32.02456  ? 12  VAL A N   1 
ATOM   3342 C CA  . VAL C 1 12  ? 12.35393  44.03734 32.10306  1.000 36.27212  ? 12  VAL A CA  1 
ATOM   3343 C C   . VAL C 1 12  ? 13.02436  42.73601 31.67287  1.000 34.38954  ? 12  VAL A C   1 
ATOM   3344 O O   . VAL C 1 12  ? 13.40933  42.57250 30.51213  1.000 34.71449  ? 12  VAL A O   1 
ATOM   3345 C CB  . VAL C 1 12  ? 10.81843  43.96332 31.87213  1.000 36.06198  ? 12  VAL A CB  1 
ATOM   3346 C CG1 . VAL C 1 12  ? 10.18606  42.89125 32.74599  1.000 46.30004  ? 12  VAL A CG1 1 
ATOM   3347 C CG2 . VAL C 1 12  ? 10.15765  45.31570 32.12639  1.000 38.92506  ? 12  VAL A CG2 1 
ATOM   3348 N N   . GLN C 1 13  ? 13.15453  41.80063 32.61427  1.000 32.01104  ? 13  GLN A N   1 
ATOM   3349 C CA  . GLN C 1 13  ? 13.72741  40.49432 32.31428  1.000 32.94588  ? 13  GLN A CA  1 
ATOM   3350 C C   . GLN C 1 13  ? 12.74332  39.63307 31.52421  1.000 30.09115  ? 13  GLN A C   1 
ATOM   3351 O O   . GLN C 1 13  ? 11.53142  39.74665 31.70455  1.000 30.65880  ? 13  GLN A O   1 
ATOM   3352 C CB  . GLN C 1 13  ? 14.09328  39.76361 33.60035  1.000 34.97005  ? 13  GLN A CB  1 
ATOM   3353 C CG  . GLN C 1 13  ? 15.32135  40.29689 34.28616  1.000 33.55264  ? 13  GLN A CG  1 
ATOM   3354 C CD  . GLN C 1 13  ? 16.57592  39.57132 33.85839  1.000 42.15164  ? 13  GLN A CD  1 
ATOM   3355 O OE1 . GLN C 1 13  ? 16.58359  38.34382 33.72335  1.000 39.97516  ? 13  GLN A OE1 1 
ATOM   3356 N NE2 . GLN C 1 13  ? 17.65009  40.32448 33.64378  1.000 35.59941  ? 13  GLN A NE2 1 
ATOM   3357 N N   . PRO C 1 14  ? 13.24101  38.76779 30.63866  1.000 27.81783  ? 14  PRO A N   1 
ATOM   3358 C CA  . PRO C 1 14  ? 12.37672  37.73430 30.05580  1.000 31.45404  ? 14  PRO A CA  1 
ATOM   3359 C C   . PRO C 1 14  ? 11.64021  36.98185 31.15448  1.000 33.77542  ? 14  PRO A C   1 
ATOM   3360 O O   . PRO C 1 14  ? 12.21213  36.65225 32.19536  1.000 28.23958  ? 14  PRO A O   1 
ATOM   3361 C CB  . PRO C 1 14  ? 13.36092  36.82990 29.30937  1.000 31.93860  ? 14  PRO A CB  1 
ATOM   3362 C CG  . PRO C 1 14  ? 14.49840  37.75714 28.94270  1.000 32.13786  ? 14  PRO A CG  1 
ATOM   3363 C CD  . PRO C 1 14  ? 14.61351  38.70793 30.10586  1.000 29.64816  ? 14  PRO A CD  1 
ATOM   3364 N N   . GLY C 1 15  ? 10.35268  36.73296 30.92421  1.000 35.00643  ? 15  GLY A N   1 
ATOM   3365 C CA  . GLY C 1 15  ? 9.51077   36.14227 31.94179  1.000 36.22700  ? 15  GLY A CA  1 
ATOM   3366 C C   . GLY C 1 15  ? 8.98967   37.10555 32.98519  1.000 39.36457  ? 15  GLY A C   1 
ATOM   3367 O O   . GLY C 1 15  ? 8.25024   36.68250 33.87685  1.000 38.46046  ? 15  GLY A O   1 
ATOM   3368 N N   . GLY C 1 16  ? 9.34104   38.38202 32.91207  1.000 41.26862  ? 16  GLY A N   1 
ATOM   3369 C CA  . GLY C 1 16  ? 8.93054   39.35608 33.90336  1.000 31.65637  ? 16  GLY A CA  1 
ATOM   3370 C C   . GLY C 1 16  ? 7.60585   40.00259 33.57054  1.000 37.65685  ? 16  GLY A C   1 
ATOM   3371 O O   . GLY C 1 16  ? 6.84334   39.52570 32.72441  1.000 38.18165  ? 16  GLY A O   1 
ATOM   3372 N N   . SER C 1 17  ? 7.33803   41.12273 34.24496  1.000 30.63317  ? 17  SER A N   1 
ATOM   3373 C CA  . SER C 1 17  ? 6.09202   41.85647 34.07594  1.000 39.63245  ? 17  SER A CA  1 
ATOM   3374 C C   . SER C 1 17  ? 6.37106   43.32147 33.78221  1.000 37.89107  ? 17  SER A C   1 
ATOM   3375 O O   . SER C 1 17  ? 7.39705   43.86949 34.18265  1.000 32.24150  ? 17  SER A O   1 
ATOM   3376 C CB  . SER C 1 17  ? 5.20321   41.75350 35.32116  1.000 40.27597  ? 17  SER A CB  1 
ATOM   3377 O OG  . SER C 1 17  ? 4.72743   40.43037 35.47862  1.000 51.71209  ? 17  SER A OG  1 
ATOM   3378 N N   . LEU C 1 18  ? 5.45237   43.94949 33.06348  1.000 35.46573  ? 18  LEU A N   1 
ATOM   3379 C CA  . LEU C 1 18  ? 5.50901   45.38008 32.83003  1.000 33.76794  ? 18  LEU A CA  1 
ATOM   3380 C C   . LEU C 1 18  ? 4.31028   46.02968 33.50133  1.000 36.47086  ? 18  LEU A C   1 
ATOM   3381 O O   . LEU C 1 18  ? 3.25358   45.41103 33.65002  1.000 35.62677  ? 18  LEU A O   1 
ATOM   3382 C CB  . LEU C 1 18  ? 5.54090   45.71296 31.32494  1.000 31.36357  ? 18  LEU A CB  1 
ATOM   3383 C CG  . LEU C 1 18  ? 4.36858   45.37161 30.38930  1.000 38.63211  ? 18  LEU A CG  1 
ATOM   3384 C CD1 . LEU C 1 18  ? 3.20067   46.35436 30.51510  1.000 36.83096  ? 18  LEU A CD1 1 
ATOM   3385 C CD2 . LEU C 1 18  ? 4.83828   45.31241 28.93729  1.000 27.40007  ? 18  LEU A CD2 1 
ATOM   3386 N N   . ARG C 1 19  ? 4.48744   47.28063 33.91330  1.000 35.57264  ? 19  ARG A N   1 
ATOM   3387 C CA  . ARG C 1 19  ? 3.40926   48.06937 34.49268  1.000 36.79439  ? 19  ARG A CA  1 
ATOM   3388 C C   . ARG C 1 19  ? 3.55584   49.47364 33.93736  1.000 34.30930  ? 19  ARG A C   1 
ATOM   3389 O O   . ARG C 1 19  ? 4.54696   50.15263 34.21912  1.000 36.27060  ? 19  ARG A O   1 
ATOM   3390 C CB  . ARG C 1 19  ? 3.46266   48.07196 36.02211  1.000 39.21522  ? 19  ARG A CB  1 
ATOM   3391 C CG  . ARG C 1 19  ? 2.25472   48.73784 36.69173  1.000 45.36305  ? 19  ARG A CG  1 
ATOM   3392 C CD  . ARG C 1 19  ? 2.63625   49.59386 37.90610  1.000 61.13522  ? 19  ARG A CD  1 
ATOM   3393 N NE  . ARG C 1 19  ? 3.55724   50.67338 37.55674  1.000 74.69757  ? 19  ARG A NE  1 
ATOM   3394 C CZ  . ARG C 1 19  ? 3.20053   51.81815 36.98457  1.000 66.83200  ? 19  ARG A CZ  1 
ATOM   3395 N NH1 . ARG C 1 19  ? 1.93825   52.07491 36.67655  1.000 63.77646  ? 19  ARG A NH1 1 
ATOM   3396 N NH2 . ARG C 1 19  ? 4.13521   52.72669 36.70847  1.000 54.32391  ? 19  ARG A NH2 1 
ATOM   3397 N N   . LEU C 1 20  ? 2.58903   49.89943 33.13760  1.000 36.93839  ? 20  LEU A N   1 
ATOM   3398 C CA  . LEU C 1 20  ? 2.59278   51.22995 32.55867  1.000 42.94072  ? 20  LEU A CA  1 
ATOM   3399 C C   . LEU C 1 20  ? 1.34338   51.98152 32.98625  1.000 47.03479  ? 20  LEU A C   1 
ATOM   3400 O O   . LEU C 1 20  ? 0.27399   51.38982 33.16610  1.000 47.53493  ? 20  LEU A O   1 
ATOM   3401 C CB  . LEU C 1 20  ? 2.65232   51.17263 31.03677  1.000 35.73002  ? 20  LEU A CB  1 
ATOM   3402 C CG  . LEU C 1 20  ? 3.73103   50.24951 30.48931  1.000 39.65765  ? 20  LEU A CG  1 
ATOM   3403 C CD1 . LEU C 1 20  ? 3.63109   50.21713 28.98200  1.000 33.53502  ? 20  LEU A CD1 1 
ATOM   3404 C CD2 . LEU C 1 20  ? 5.10501   50.71569 30.93276  1.000 31.37756  ? 20  LEU A CD2 1 
ATOM   3405 N N   . SER C 1 21  ? 1.48157   53.29599 33.12368  1.000 41.42020  ? 21  SER A N   1 
ATOM   3406 C CA  . SER C 1 21  ? 0.38444   54.14449 33.55301  1.000 50.52406  ? 21  SER A CA  1 
ATOM   3407 C C   . SER C 1 21  ? 0.28283   55.34789 32.63018  1.000 48.98780  ? 21  SER A C   1 
ATOM   3408 O O   . SER C 1 21  ? 1.27692   55.78585 32.04737  1.000 44.45933  ? 21  SER A O   1 
ATOM   3409 C CB  . SER C 1 21  ? 0.57983   54.59830 35.00930  1.000 52.29454  ? 21  SER A CB  1 
ATOM   3410 O OG  . SER C 1 21  ? -0.66473  54.72855 35.66994  1.000 58.26311  ? 21  SER A OG  1 
ATOM   3411 N N   . CYS C 1 22  ? -0.93588  55.86584 32.48682  1.000 46.23978  ? 22  CYS A N   1 
ATOM   3412 C CA  . CYS C 1 22  ? -1.19442  57.06946 31.70629  1.000 51.28709  ? 22  CYS A CA  1 
ATOM   3413 C C   . CYS C 1 22  ? -2.03902  58.02359 32.53141  1.000 51.13398  ? 22  CYS A C   1 
ATOM   3414 O O   . CYS C 1 22  ? -3.14351  57.66583 32.95037  1.000 49.71613  ? 22  CYS A O   1 
ATOM   3415 C CB  . CYS C 1 22  ? -1.90300  56.74494 30.39118  1.000 51.40229  ? 22  CYS A CB  1 
ATOM   3416 S SG  . CYS C 1 22  ? -0.78246  56.77816 28.99623  1.000 71.94543  ? 22  CYS A SG  1 
ATOM   3417 N N   . THR C 1 23  ? -1.53340  59.23744 32.73592  1.000 48.61435  ? 23  THR A N   1 
ATOM   3418 C CA  . THR C 1 23  ? -2.19250  60.24442 33.55989  1.000 55.34826  ? 23  THR A CA  1 
ATOM   3419 C C   . THR C 1 23  ? -2.82564  61.29744 32.65744  1.000 47.30549  ? 23  THR A C   1 
ATOM   3420 O O   . THR C 1 23  ? -2.13937  61.90620 31.83075  1.000 53.95537  ? 23  THR A O   1 
ATOM   3421 C CB  . THR C 1 23  ? -1.19714  60.89333 34.52321  1.000 54.82711  ? 23  THR A CB  1 
ATOM   3422 O OG1 . THR C 1 23  ? -0.35379  59.88347 35.08804  1.000 63.52088  ? 23  THR A OG1 1 
ATOM   3423 C CG2 . THR C 1 23  ? -1.92594  61.61126 35.64823  1.000 49.94776  ? 23  THR A CG2 1 
ATOM   3424 N N   . ALA C 1 24  ? -4.12817  61.50471 32.81317  1.000 53.94082  ? 24  ALA A N   1 
ATOM   3425 C CA  . ALA C 1 24  ? -4.82167  62.53998 32.06556  1.000 56.51154  ? 24  ALA A CA  1 
ATOM   3426 C C   . ALA C 1 24  ? -4.55070  63.91039 32.66822  1.000 59.94370  ? 24  ALA A C   1 
ATOM   3427 O O   . ALA C 1 24  ? -4.32930  64.05344 33.87306  1.000 57.70847  ? 24  ALA A O   1 
ATOM   3428 C CB  . ALA C 1 24  ? -6.32497  62.28051 32.04709  1.000 57.38077  ? 24  ALA A CB  1 
ATOM   3429 N N   . SER C 1 25  ? -4.57046  64.92546 31.81098  1.000 61.86499  ? 25  SER A N   1 
ATOM   3430 C CA  . SER C 1 25  ? -4.46182  66.31306 32.24341  1.000 58.78252  ? 25  SER A CA  1 
ATOM   3431 C C   . SER C 1 25  ? -5.37179  67.14888 31.36381  1.000 64.36212  ? 25  SER A C   1 
ATOM   3432 O O   . SER C 1 25  ? -5.21976  67.15109 30.13939  1.000 62.29860  ? 25  SER A O   1 
ATOM   3433 C CB  . SER C 1 25  ? -3.02060  66.81727 32.16471  1.000 64.10565  ? 25  SER A CB  1 
ATOM   3434 O OG  . SER C 1 25  ? -2.28822  66.39024 33.29779  1.000 79.95418  ? 25  SER A OG  1 
ATOM   3435 N N   . GLY C 1 26  ? -6.31674  67.84717 31.98433  1.000 56.98884  ? 26  GLY A N   1 
ATOM   3436 C CA  . GLY C 1 26  ? -7.29180  68.62897 31.25923  1.000 60.88393  ? 26  GLY A CA  1 
ATOM   3437 C C   . GLY C 1 26  ? -8.64818  67.97948 31.13259  1.000 65.32966  ? 26  GLY A C   1 
ATOM   3438 O O   . GLY C 1 26  ? -9.53337  68.55475 30.48838  1.000 74.20424  ? 26  GLY A O   1 
ATOM   3439 N N   . PHE C 1 27  ? -8.83729  66.80773 31.72348  1.000 61.68775  ? 27  PHE A N   1 
ATOM   3440 C CA  . PHE C 1 27  ? -10.10870 66.09286 31.69330  1.000 62.15424  ? 27  PHE A CA  1 
ATOM   3441 C C   . PHE C 1 27  ? -9.99771  64.93202 32.67555  1.000 61.40436  ? 27  PHE A C   1 
ATOM   3442 O O   . PHE C 1 27  ? -8.94686  64.70811 33.28563  1.000 53.89194  ? 27  PHE A O   1 
ATOM   3443 C CB  . PHE C 1 27  ? -10.45601 65.61106 30.28103  1.000 62.27302  ? 27  PHE A CB  1 
ATOM   3444 C CG  . PHE C 1 27  ? -9.52966  64.55203 29.75620  1.000 61.86221  ? 27  PHE A CG  1 
ATOM   3445 C CD1 . PHE C 1 27  ? -8.21893  64.86012 29.41651  1.000 62.45030  ? 27  PHE A CD1 1 
ATOM   3446 C CD2 . PHE C 1 27  ? -9.97032  63.24925 29.59793  1.000 55.75895  ? 27  PHE A CD2 1 
ATOM   3447 C CE1 . PHE C 1 27  ? -7.36379  63.88680 28.93754  1.000 61.21328  ? 27  PHE A CE1 1 
ATOM   3448 C CE2 . PHE C 1 27  ? -9.12026  62.27255 29.11748  1.000 51.48601  ? 27  PHE A CE2 1 
ATOM   3449 C CZ  . PHE C 1 27  ? -7.81469  62.59075 28.78597  1.000 54.96724  ? 27  PHE A CZ  1 
ATOM   3450 N N   . SER C 1 28  ? -11.09619 64.19878 32.82882  1.000 65.49750  ? 28  SER A N   1 
ATOM   3451 C CA  . SER C 1 28  ? -11.14478 63.02224 33.68369  1.000 62.28736  ? 28  SER A CA  1 
ATOM   3452 C C   . SER C 1 28  ? -11.07058 61.77359 32.81804  1.000 56.69209  ? 28  SER A C   1 
ATOM   3453 O O   . SER C 1 28  ? -11.74939 61.68334 31.79170  1.000 46.58962  ? 28  SER A O   1 
ATOM   3454 C CB  . SER C 1 28  ? -12.42788 63.00430 34.51967  1.000 67.40856  ? 28  SER A CB  1 
ATOM   3455 O OG  . SER C 1 28  ? -12.70818 64.28470 35.06104  1.000 68.66988  ? 28  SER A OG  1 
ATOM   3456 N N   . ILE C 1 29  ? -10.24464 60.80924 33.23655  1.000 56.83907  ? 29  ILE A N   1 
ATOM   3457 C CA  . ILE C 1 29  ? -10.07150 59.59319 32.44720  1.000 54.91838  ? 29  ILE A CA  1 
ATOM   3458 C C   . ILE C 1 29  ? -11.34998 58.77877 32.37764  1.000 56.48341  ? 29  ILE A C   1 
ATOM   3459 O O   . ILE C 1 29  ? -11.50712 57.95647 31.46789  1.000 51.40730  ? 29  ILE A O   1 
ATOM   3460 C CB  . ILE C 1 29  ? -8.91777  58.73540 33.00207  1.000 54.02027  ? 29  ILE A CB  1 
ATOM   3461 C CG1 . ILE C 1 29  ? -8.76002  58.97533 34.49453  1.000 51.60905  ? 29  ILE A CG1 1 
ATOM   3462 C CG2 . ILE C 1 29  ? -7.62139  59.00339 32.25081  1.000 60.20207  ? 29  ILE A CG2 1 
ATOM   3463 C CD1 . ILE C 1 29  ? -9.73003  58.20136 35.31789  1.000 59.51726  ? 29  ILE A CD1 1 
ATOM   3464 N N   . ASP C 1 30  ? -12.27522 58.98205 33.31879  1.000 58.91434  ? 30  ASP A N   1 
ATOM   3465 C CA  . ASP C 1 30  ? -13.56239 58.29829 33.26758  1.000 59.98611  ? 30  ASP A CA  1 
ATOM   3466 C C   . ASP C 1 30  ? -14.53416 58.94504 32.29109  1.000 57.24899  ? 30  ASP A C   1 
ATOM   3467 O O   . ASP C 1 30  ? -15.65841 58.45196 32.14814  1.000 56.34057  ? 30  ASP A O   1 
ATOM   3468 C CB  . ASP C 1 30  ? -14.19741 58.23839 34.66121  1.000 60.13392  ? 30  ASP A CB  1 
ATOM   3469 C CG  . ASP C 1 30  ? -14.21659 59.58953 35.35497  1.000 64.45658  ? 30  ASP A CG  1 
ATOM   3470 O OD1 . ASP C 1 30  ? -14.92699 60.50206 34.88230  1.000 73.57106  ? 30  ASP A OD1 1 
ATOM   3471 O OD2 . ASP C 1 30  ? -13.51716 59.73928 36.37622  1.000 71.81044  ? 30  ASP A OD2 1 
ATOM   3472 N N   . SER C 1 31  ? -14.13698 60.03497 31.62606  1.000 51.28597  ? 31  SER A N   1 
ATOM   3473 C CA  . SER C 1 31  ? -15.00770 60.64058 30.62269  1.000 53.93323  ? 31  SER A CA  1 
ATOM   3474 C C   . SER C 1 31  ? -15.05764 59.80513 29.35032  1.000 46.04151  ? 31  SER A C   1 
ATOM   3475 O O   . SER C 1 31  ? -16.09430 59.76152 28.67933  1.000 44.20597  ? 31  SER A O   1 
ATOM   3476 C CB  . SER C 1 31  ? -14.54257 62.06339 30.29507  1.000 51.50666  ? 31  SER A CB  1 
ATOM   3477 O OG  . SER C 1 31  ? -14.73193 62.94513 31.38714  1.000 59.60247  ? 31  SER A OG  1 
ATOM   3478 N N   . TYR C 1 32  ? -13.95739 59.13857 29.00596  1.000 50.73352  ? 32  TYR A N   1 
ATOM   3479 C CA  . TYR C 1 32  ? -13.84896 58.39489 27.76062  1.000 47.41950  ? 32  TYR A CA  1 
ATOM   3480 C C   . TYR C 1 32  ? -13.27376 57.01042 28.03088  1.000 47.38706  ? 32  TYR A C   1 
ATOM   3481 O O   . TYR C 1 32  ? -12.65224 56.76179 29.07032  1.000 47.33718  ? 32  TYR A O   1 
ATOM   3482 C CB  . TYR C 1 32  ? -12.94994 59.10837 26.74446  1.000 46.90138  ? 32  TYR A CB  1 
ATOM   3483 C CG  . TYR C 1 32  ? -13.15628 60.59815 26.58906  1.000 45.31233  ? 32  TYR A CG  1 
ATOM   3484 C CD1 . TYR C 1 32  ? -14.24364 61.10422 25.88346  1.000 57.07049  ? 32  TYR A CD1 1 
ATOM   3485 C CD2 . TYR C 1 32  ? -12.23313 61.50083 27.10763  1.000 50.35743  ? 32  TYR A CD2 1 
ATOM   3486 C CE1 . TYR C 1 32  ? -14.42020 62.47708 25.71842  1.000 48.55913  ? 32  TYR A CE1 1 
ATOM   3487 C CE2 . TYR C 1 32  ? -12.39849 62.86913 26.95462  1.000 53.49908  ? 32  TYR A CE2 1 
ATOM   3488 C CZ  . TYR C 1 32  ? -13.49135 63.35392 26.25689  1.000 56.30899  ? 32  TYR A CZ  1 
ATOM   3489 O OH  . TYR C 1 32  ? -13.64561 64.71701 26.10323  1.000 54.53163  ? 32  TYR A OH  1 
ATOM   3490 N N   . GLY C 1 33  ? -13.48086 56.10833 27.07030  1.000 41.19411  ? 33  GLY A N   1 
ATOM   3491 C CA  . GLY C 1 33  ? -12.74693 54.85943 27.06474  1.000 43.60676  ? 33  GLY A CA  1 
ATOM   3492 C C   . GLY C 1 33  ? -11.35788 55.02443 26.46286  1.000 41.53729  ? 33  GLY A C   1 
ATOM   3493 O O   . GLY C 1 33  ? -11.12725 55.84953 25.57279  1.000 39.96325  ? 33  GLY A O   1 
ATOM   3494 N N   . PHE C 1 34  ? -10.41446 54.21624 26.95856  1.000 33.15111  ? 34  PHE A N   1 
ATOM   3495 C CA  . PHE C 1 34  ? -9.01841  54.28088 26.52819  1.000 34.08709  ? 34  PHE A CA  1 
ATOM   3496 C C   . PHE C 1 34  ? -8.48190  52.89595 26.18751  1.000 32.45050  ? 34  PHE A C   1 
ATOM   3497 O O   . PHE C 1 34  ? -8.75002  51.92106 26.90169  1.000 36.53979  ? 34  PHE A O   1 
ATOM   3498 C CB  . PHE C 1 34  ? -8.12672  54.91217 27.59499  1.000 38.99338  ? 34  PHE A CB  1 
ATOM   3499 C CG  . PHE C 1 34  ? -8.33672  56.38314 27.75383  1.000 43.31436  ? 34  PHE A CG  1 
ATOM   3500 C CD1 . PHE C 1 34  ? -7.63116  57.28318 26.97488  1.000 42.32681  ? 34  PHE A CD1 1 
ATOM   3501 C CD2 . PHE C 1 34  ? -9.25865  56.86710 28.66825  1.000 48.25773  ? 34  PHE A CD2 1 
ATOM   3502 C CE1 . PHE C 1 34  ? -7.82959  58.63373 27.11215  1.000 47.15641  ? 34  PHE A CE1 1 
ATOM   3503 C CE2 . PHE C 1 34  ? -9.46255  58.22251 28.81055  1.000 50.60931  ? 34  PHE A CE2 1 
ATOM   3504 C CZ  . PHE C 1 34  ? -8.74527  59.10689 28.03246  1.000 52.06258  ? 34  PHE A CZ  1 
ATOM   3505 N N   . SER C 1 35  ? -7.71957  52.82980 25.09426  1.000 28.71352  ? 35  SER A N   1 
ATOM   3506 C CA  . SER C 1 35  ? -7.03466  51.63779 24.61591  1.000 33.22675  ? 35  SER A CA  1 
ATOM   3507 C C   . SER C 1 35  ? -5.55416  51.68048 24.97700  1.000 30.34374  ? 35  SER A C   1 
ATOM   3508 O O   . SER C 1 35  ? -4.97733  52.74194 25.21910  1.000 33.51994  ? 35  SER A O   1 
ATOM   3509 C CB  . SER C 1 35  ? -7.15540  51.50541 23.09382  1.000 29.04570  ? 35  SER A CB  1 
ATOM   3510 O OG  . SER C 1 35  ? -8.49992  51.52548 22.66252  1.000 32.33917  ? 35  SER A OG  1 
ATOM   3511 N N   . TRP C 1 36  ? -4.94147  50.50289 24.98616  1.000 30.00869  ? 36  TRP A N   1 
ATOM   3512 C CA  . TRP C 1 36  ? -3.49417  50.35590 24.96705  1.000 33.17279  ? 36  TRP A CA  1 
ATOM   3513 C C   . TRP C 1 36  ? -3.10234  49.73376 23.63547  1.000 31.53962  ? 36  TRP A C   1 
ATOM   3514 O O   . TRP C 1 36  ? -3.73903  48.77816 23.18061  1.000 31.02951  ? 36  TRP A O   1 
ATOM   3515 C CB  . TRP C 1 36  ? -2.99283  49.49984 26.13227  1.000 28.96573  ? 36  TRP A CB  1 
ATOM   3516 C CG  . TRP C 1 36  ? -2.98053  50.21920 27.44100  1.000 30.20089  ? 36  TRP A CG  1 
ATOM   3517 C CD1 . TRP C 1 36  ? -3.95928  50.20859 28.39202  1.000 32.40958  ? 36  TRP A CD1 1 
ATOM   3518 C CD2 . TRP C 1 36  ? -1.93993  51.05754 27.94682  1.000 39.37797  ? 36  TRP A CD2 1 
ATOM   3519 N NE1 . TRP C 1 36  ? -3.58867  50.98623 29.46217  1.000 38.33195  ? 36  TRP A NE1 1 
ATOM   3520 C CE2 . TRP C 1 36  ? -2.35359  51.52271 29.21072  1.000 45.30522  ? 36  TRP A CE2 1 
ATOM   3521 C CE3 . TRP C 1 36  ? -0.69435  51.46066 27.45450  1.000 41.05202  ? 36  TRP A CE3 1 
ATOM   3522 C CZ2 . TRP C 1 36  ? -1.56327  52.36710 29.99029  1.000 45.93654  ? 36  TRP A CZ2 1 
ATOM   3523 C CZ3 . TRP C 1 36  ? 0.08203   52.29720 28.22296  1.000 30.44310  ? 36  TRP A CZ3 1 
ATOM   3524 C CH2 . TRP C 1 36  ? -0.35201  52.74366 29.47706  1.000 44.24369  ? 36  TRP A CH2 1 
ATOM   3525 N N   . VAL C 1 37  ? -2.08136  50.30527 23.00084  1.000 27.60634  ? 37  VAL A N   1 
ATOM   3526 C CA  . VAL C 1 37  ? -1.57809  49.88384 21.69878  1.000 27.33515  ? 37  VAL A CA  1 
ATOM   3527 C C   . VAL C 1 37  ? -0.06605  49.76833 21.81663  1.000 31.07979  ? 37  VAL A C   1 
ATOM   3528 O O   . VAL C 1 37  ? 0.55754   50.43564 22.64864  1.000 34.30864  ? 37  VAL A O   1 
ATOM   3529 C CB  . VAL C 1 37  ? -1.97278  50.89515 20.59082  1.000 35.77087  ? 37  VAL A CB  1 
ATOM   3530 C CG1 . VAL C 1 37  ? -1.40544  50.49475 19.22182  1.000 35.78553  ? 37  VAL A CG1 1 
ATOM   3531 C CG2 . VAL C 1 37  ? -3.49373  51.05409 20.53022  1.000 34.11307  ? 37  VAL A CG2 1 
ATOM   3532 N N   . ARG C 1 38  ? 0.53244   48.90233 21.00668  1.000 28.66684  ? 38  ARG A N   1 
ATOM   3533 C CA  . ARG C 1 38  ? 1.98352   48.81728 20.99430  1.000 29.21655  ? 38  ARG A CA  1 
ATOM   3534 C C   . ARG C 1 38  ? 2.48397   48.71519 19.56069  1.000 30.36850  ? 38  ARG A C   1 
ATOM   3535 O O   . ARG C 1 38  ? 1.71674   48.47106 18.62576  1.000 30.43639  ? 38  ARG A O   1 
ATOM   3536 C CB  . ARG C 1 38  ? 2.48774   47.63828 21.83002  1.000 29.26238  ? 38  ARG A CB  1 
ATOM   3537 C CG  . ARG C 1 38  ? 2.31709   46.29347 21.16248  1.000 35.87553  ? 38  ARG A CG  1 
ATOM   3538 C CD  . ARG C 1 38  ? 2.81334   45.19486 22.06762  1.000 29.49937  ? 38  ARG A CD  1 
ATOM   3539 N NE  . ARG C 1 38  ? 2.74544   43.89498 21.41762  1.000 34.17805  ? 38  ARG A NE  1 
ATOM   3540 C CZ  . ARG C 1 38  ? 3.13828   42.76301 21.98160  1.000 33.16518  ? 38  ARG A CZ  1 
ATOM   3541 N NH1 . ARG C 1 38  ? 3.60248   42.73443 23.22020  1.000 29.29853  ? 38  ARG A NH1 1 
ATOM   3542 N NH2 . ARG C 1 38  ? 3.06335   41.63265 21.28617  1.000 39.35011  ? 38  ARG A NH2 1 
ATOM   3543 N N   . GLN C 1 39  ? 3.78953   48.93942 19.39880  1.000 28.14952  ? 39  GLN A N   1 
ATOM   3544 C CA  . GLN C 1 39  ? 4.43913   48.88645 18.08866  1.000 27.15648  ? 39  GLN A CA  1 
ATOM   3545 C C   . GLN C 1 39  ? 5.87728   48.43889 18.30829  1.000 34.12999  ? 39  GLN A C   1 
ATOM   3546 O O   . GLN C 1 39  ? 6.69398   49.20591 18.83016  1.000 27.70063  ? 39  GLN A O   1 
ATOM   3547 C CB  . GLN C 1 39  ? 4.38719   50.24575 17.38872  1.000 32.17129  ? 39  GLN A CB  1 
ATOM   3548 C CG  . GLN C 1 39  ? 4.97905   50.26415 15.97185  1.000 29.14460  ? 39  GLN A CG  1 
ATOM   3549 C CD  . GLN C 1 39  ? 4.78842   51.59823 15.26735  1.000 39.09704  ? 39  GLN A CD  1 
ATOM   3550 O OE1 . GLN C 1 39  ? 4.90029   52.66573 15.88399  1.000 32.70102  ? 39  GLN A OE1 1 
ATOM   3551 N NE2 . GLN C 1 39  ? 4.49354   51.54658 13.96512  1.000 34.41006  ? 39  GLN A NE2 1 
ATOM   3552 N N   . ALA C 1 40  ? 6.18179   47.20037 17.93734  1.000 33.06574  ? 40  ALA A N   1 
ATOM   3553 C CA  . ALA C 1 40  ? 7.55627   46.72813 17.99870  1.000 31.35503  ? 40  ALA A CA  1 
ATOM   3554 C C   . ALA C 1 40  ? 8.39520   47.44791 16.93965  1.000 39.28255  ? 40  ALA A C   1 
ATOM   3555 O O   . ALA C 1 40  ? 7.85825   47.94872 15.94762  1.000 36.41837  ? 40  ALA A O   1 
ATOM   3556 C CB  . ALA C 1 40  ? 7.60559   45.21453 17.80921  1.000 29.30460  ? 40  ALA A CB  1 
ATOM   3557 N N   . PRO C 1 41  ? 9.71313   47.53894 17.13648  1.000 38.25096  ? 41  PRO A N   1 
ATOM   3558 C CA  . PRO C 1 41  ? 10.52791  48.37009 16.23107  1.000 40.11903  ? 41  PRO A CA  1 
ATOM   3559 C C   . PRO C 1 41  ? 10.46410  47.85838 14.79767  1.000 37.23895  ? 41  PRO A C   1 
ATOM   3560 O O   . PRO C 1 41  ? 10.70939  46.67899 14.52246  1.000 40.39380  ? 41  PRO A O   1 
ATOM   3561 C CB  . PRO C 1 41  ? 11.93869  48.26941 16.82814  1.000 39.87316  ? 41  PRO A CB  1 
ATOM   3562 C CG  . PRO C 1 41  ? 11.92417  47.02487 17.66626  1.000 44.08260  ? 41  PRO A CG  1 
ATOM   3563 C CD  . PRO C 1 41  ? 10.52641  46.92695 18.20677  1.000 35.46846  ? 41  PRO A CD  1 
ATOM   3564 N N   . GLY C 1 42  ? 10.08625  48.75494 13.88671  1.000 40.11223  ? 42  GLY A N   1 
ATOM   3565 C CA  . GLY C 1 42  ? 9.91924   48.42253 12.48672  1.000 45.23502  ? 42  GLY A CA  1 
ATOM   3566 C C   . GLY C 1 42  ? 8.63384   47.70399 12.11130  1.000 46.23446  ? 42  GLY A C   1 
ATOM   3567 O O   . GLY C 1 42  ? 8.46364   47.36900 10.93209  1.000 48.46222  ? 42  GLY A O   1 
ATOM   3568 N N   . LYS C 1 43  ? 7.71341   47.46144 13.05453  1.000 38.18785  ? 43  LYS A N   1 
ATOM   3569 C CA  . LYS C 1 43  ? 6.49491   46.71710 12.76469  1.000 35.77998  ? 43  LYS A CA  1 
ATOM   3570 C C   . LYS C 1 43  ? 5.28040   47.64087 12.84718  1.000 36.99599  ? 43  LYS A C   1 
ATOM   3571 O O   . LYS C 1 43  ? 5.40282   48.86004 13.00149  1.000 32.51101  ? 43  LYS A O   1 
ATOM   3572 C CB  . LYS C 1 43  ? 6.34773   45.53062 13.71891  1.000 36.11383  ? 43  LYS A CB  1 
ATOM   3573 C CG  . LYS C 1 43  ? 7.64670   44.84186 14.07382  1.000 42.74196  ? 43  LYS A CG  1 
ATOM   3574 C CD  . LYS C 1 43  ? 8.27905   44.17981 12.86687  1.000 47.52387  ? 43  LYS A CD  1 
ATOM   3575 C CE  . LYS C 1 43  ? 9.61391   43.53597 13.23664  1.000 55.26199  ? 43  LYS A CE  1 
ATOM   3576 N NZ  . LYS C 1 43  ? 9.50289   42.67701 14.46576  1.000 60.58509  ? 43  LYS A NZ  1 
ATOM   3577 N N   . GLY C 1 44  ? 4.08699   47.04819 12.76116  1.000 35.40129  ? 44  GLY A N   1 
ATOM   3578 C CA  . GLY C 1 44  ? 2.85746   47.81475 12.74053  1.000 29.57644  ? 44  GLY A CA  1 
ATOM   3579 C C   . GLY C 1 44  ? 2.24613   48.01568 14.11561  1.000 33.30660  ? 44  GLY A C   1 
ATOM   3580 O O   . GLY C 1 44  ? 2.74078   47.53606 15.13552  1.000 34.91475  ? 44  GLY A O   1 
ATOM   3581 N N   . LEU C 1 45  ? 1.14143   48.75699 14.12769  1.000 33.78426  ? 45  LEU A N   1 
ATOM   3582 C CA  . LEU C 1 45  ? 0.39261   48.99966 15.35380  1.000 34.92321  ? 45  LEU A CA  1 
ATOM   3583 C C   . LEU C 1 45  ? -0.44655  47.78011 15.72180  1.000 39.23392  ? 45  LEU A C   1 
ATOM   3584 O O   . LEU C 1 45  ? -1.05531  47.14210 14.85987  1.000 36.70070  ? 45  LEU A O   1 
ATOM   3585 C CB  . LEU C 1 45  ? -0.50748  50.22271 15.18611  1.000 33.37476  ? 45  LEU A CB  1 
ATOM   3586 C CG  . LEU C 1 45  ? 0.21827   51.50038 14.77040  1.000 31.01943  ? 45  LEU A CG  1 
ATOM   3587 C CD1 . LEU C 1 45  ? -0.77416  52.58843 14.42093  1.000 34.29287  ? 45  LEU A CD1 1 
ATOM   3588 C CD2 . LEU C 1 45  ? 1.14706   51.96567 15.87954  1.000 35.70340  ? 45  LEU A CD2 1 
ATOM   3589 N N   . GLU C 1 46  ? -0.49124  47.46736 17.01526  1.000 35.92682  ? 46  GLU A N   1 
ATOM   3590 C CA  . GLU C 1 46  ? -1.14886  46.26273 17.50856  1.000 34.16734  ? 46  GLU A CA  1 
ATOM   3591 C C   . GLU C 1 46  ? -2.01180  46.61646 18.71314  1.000 34.84629  ? 46  GLU A C   1 
ATOM   3592 O O   . GLU C 1 46  ? -1.50299  47.13114 19.71703  1.000 30.61800  ? 46  GLU A O   1 
ATOM   3593 C CB  . GLU C 1 46  ? -0.10874  45.19900 17.87022  1.000 38.22614  ? 46  GLU A CB  1 
ATOM   3594 C CG  . GLU C 1 46  ? -0.69296  43.86863 18.29974  1.000 40.17403  ? 46  GLU A CG  1 
ATOM   3595 C CD  . GLU C 1 46  ? 0.32632   42.74442 18.25381  1.000 52.53928  ? 46  GLU A CD  1 
ATOM   3596 O OE1 . GLU C 1 46  ? 1.54528   43.03167 18.31787  1.000 54.65219  ? 46  GLU A OE1 1 
ATOM   3597 O OE2 . GLU C 1 46  ? -0.09555  41.57224 18.14277  1.000 60.01146  ? 46  GLU A OE2 1 
ATOM   3598 N N   . HIS C 1 47  ? -3.31349  46.34381 18.61667  1.000 30.89936  ? 47  HIS A N   1 
ATOM   3599 C CA  . HIS C 1 47  ? -4.22458  46.66618 19.70471  1.000 33.91252  ? 47  HIS A CA  1 
ATOM   3600 C C   . HIS C 1 47  ? -4.08364  45.63064 20.80778  1.000 38.59470  ? 47  HIS A C   1 
ATOM   3601 O O   . HIS C 1 47  ? -3.98878  44.42907 20.54195  1.000 45.42294  ? 47  HIS A O   1 
ATOM   3602 C CB  . HIS C 1 47  ? -5.67887  46.73025 19.21961  1.000 32.76425  ? 47  HIS A CB  1 
ATOM   3603 C CG  . HIS C 1 47  ? -6.61530  47.32637 20.22761  1.000 37.65826  ? 47  HIS A CG  1 
ATOM   3604 N ND1 . HIS C 1 47  ? -7.49561  46.56713 20.96879  1.000 26.88865  ? 47  HIS A ND1 1 
ATOM   3605 C CD2 . HIS C 1 47  ? -6.77807  48.60560 20.64653  1.000 40.55388  ? 47  HIS A CD2 1 
ATOM   3606 C CE1 . HIS C 1 47  ? -8.17783  47.35547 21.78244  1.000 33.86074  ? 47  HIS A CE1 1 
ATOM   3607 N NE2 . HIS C 1 47  ? -7.76063  48.59757 21.60879  1.000 36.33257  ? 47  HIS A NE2 1 
ATOM   3608 N N   . ILE C 1 48  ? -4.05272  46.10316 22.04853  1.000 32.44649  ? 48  ILE A N   1 
ATOM   3609 C CA  . ILE C 1 48  ? -3.89506  45.23509 23.20579  1.000 32.42845  ? 48  ILE A CA  1 
ATOM   3610 C C   . ILE C 1 48  ? -5.20951  45.05083 23.94937  1.000 34.41160  ? 48  ILE A C   1 
ATOM   3611 O O   . ILE C 1 48  ? -5.64392  43.92219 24.18392  1.000 38.21291  ? 48  ILE A O   1 
ATOM   3612 C CB  . ILE C 1 48  ? -2.79583  45.78130 24.14241  1.000 36.52779  ? 48  ILE A CB  1 
ATOM   3613 C CG1 . ILE C 1 48  ? -1.43136  45.75337 23.43872  1.000 26.68613  ? 48  ILE A CG1 1 
ATOM   3614 C CG2 . ILE C 1 48  ? -2.77600  44.97537 25.42616  1.000 28.76830  ? 48  ILE A CG2 1 
ATOM   3615 C CD1 . ILE C 1 48  ? -0.34142  46.47972 24.21919  1.000 30.15449  ? 48  ILE A CD1 1 
ATOM   3616 N N   . GLY C 1 49  ? -5.84955  46.14818 24.34127  1.000 35.29017  ? 49  GLY A N   1 
ATOM   3617 C CA  . GLY C 1 49  ? -7.08721  46.05195 25.09389  1.000 35.91253  ? 49  GLY A CA  1 
ATOM   3618 C C   . GLY C 1 49  ? -7.70706  47.41772 25.27012  1.000 39.90757  ? 49  GLY A C   1 
ATOM   3619 O O   . GLY C 1 49  ? -7.05458  48.45078 25.08637  1.000 30.41516  ? 49  GLY A O   1 
ATOM   3620 N N   . TYR C 1 50  ? -8.98201  47.40130 25.66254  1.000 32.11469  ? 50  TYR A N   1 
ATOM   3621 C CA  . TYR C 1 50  ? -9.81311  48.59757 25.74329  1.000 34.54921  ? 50  TYR A CA  1 
ATOM   3622 C C   . TYR C 1 50  ? -10.55967 48.61735 27.07299  1.000 35.52380  ? 50  TYR A C   1 
ATOM   3623 O O   . TYR C 1 50  ? -11.21571 47.63738 27.43482  1.000 41.94406  ? 50  TYR A O   1 
ATOM   3624 C CB  . TYR C 1 50  ? -10.79826 48.63046 24.56967  1.000 30.98687  ? 50  TYR A CB  1 
ATOM   3625 C CG  . TYR C 1 50  ? -11.66951 49.87484 24.47657  1.000 36.62715  ? 50  TYR A CG  1 
ATOM   3626 C CD1 . TYR C 1 50  ? -11.10574 51.13532 24.32369  1.000 33.55789  ? 50  TYR A CD1 1 
ATOM   3627 C CD2 . TYR C 1 50  ? -13.05777 49.77680 24.50508  1.000 37.97515  ? 50  TYR A CD2 1 
ATOM   3628 C CE1 . TYR C 1 50  ? -11.89219 52.26797 24.22761  1.000 37.02336  ? 50  TYR A CE1 1 
ATOM   3629 C CE2 . TYR C 1 50  ? -13.85540 50.89968 24.40026  1.000 39.54690  ? 50  TYR A CE2 1 
ATOM   3630 C CZ  . TYR C 1 50  ? -13.26753 52.14189 24.26323  1.000 37.83017  ? 50  TYR A CZ  1 
ATOM   3631 O OH  . TYR C 1 50  ? -14.06037 53.25704 24.15525  1.000 49.25568  ? 50  TYR A OH  1 
ATOM   3632 N N   . LEU C 1 51  ? -10.46279 49.72881 27.79726  1.000 40.45396  ? 51  LEU A N   1 
ATOM   3633 C CA  . LEU C 1 51  ? -11.18569 49.92537 29.05092  1.000 41.32995  ? 51  LEU A CA  1 
ATOM   3634 C C   . LEU C 1 51  ? -12.30981 50.92259 28.78171  1.000 45.77433  ? 51  LEU A C   1 
ATOM   3635 O O   . LEU C 1 51  ? -12.04785 52.11383 28.57437  1.000 42.09312  ? 51  LEU A O   1 
ATOM   3636 C CB  . LEU C 1 51  ? -10.24456 50.42253 30.14892  1.000 37.88024  ? 51  LEU A CB  1 
ATOM   3637 C CG  . LEU C 1 51  ? -10.86704 50.67389 31.52442  1.000 47.03377  ? 51  LEU A CG  1 
ATOM   3638 C CD1 . LEU C 1 51  ? -11.47303 49.38466 32.07028  1.000 47.35767  ? 51  LEU A CD1 1 
ATOM   3639 C CD2 . LEU C 1 51  ? -9.84164  51.24763 32.49892  1.000 47.02889  ? 51  LEU A CD2 1 
ATOM   3640 N N   . THR C 1 52  ? -13.55520 50.44278 28.77728  1.000 38.36745  ? 52  THR A N   1 
ATOM   3641 C CA  . THR C 1 52  ? -14.65690 51.29617 28.35714  1.000 39.86526  ? 52  THR A CA  1 
ATOM   3642 C C   . THR C 1 52  ? -14.81840 52.47827 29.31103  1.000 51.78105  ? 52  THR A C   1 
ATOM   3643 O O   . THR C 1 52  ? -14.31494 52.47717 30.44154  1.000 49.03759  ? 52  THR A O   1 
ATOM   3644 C CB  . THR C 1 52  ? -15.96126 50.50570 28.28097  1.000 47.48657  ? 52  THR A CB  1 
ATOM   3645 O OG1 . THR C 1 52  ? -16.41741 50.19275 29.60726  1.000 49.50473  ? 52  THR A OG1 1 
ATOM   3646 C CG2 . THR C 1 52  ? -15.75264 49.21344 27.48580  1.000 40.00241  ? 52  THR A CG2 1 
ATOM   3647 N N   . ALA C 1 53  ? -15.51663 53.51357 28.82618  1.000 42.79687  ? 53  ALA A N   1 
ATOM   3648 C CA  . ALA C 1 53  ? -15.85767 54.64149 29.68762  1.000 50.14518  ? 53  ALA A CA  1 
ATOM   3649 C C   . ALA C 1 53  ? -16.59849 54.18253 30.93937  1.000 53.95016  ? 53  ALA A C   1 
ATOM   3650 O O   . ALA C 1 53  ? -16.48865 54.81926 31.99577  1.000 50.53896  ? 53  ALA A O   1 
ATOM   3651 C CB  . ALA C 1 53  ? -16.69353 55.66018 28.91200  1.000 50.73517  ? 53  ALA A CB  1 
ATOM   3652 N N   . GLY C 1 54  ? -17.33656 53.07296 30.84616  1.000 48.78914  ? 54  GLY A N   1 
ATOM   3653 C CA  . GLY C 1 54  ? -18.02788 52.47669 31.97133  1.000 52.82287  ? 54  GLY A CA  1 
ATOM   3654 C C   . GLY C 1 54  ? -17.17947 51.62662 32.89107  1.000 54.71878  ? 54  GLY A C   1 
ATOM   3655 O O   . GLY C 1 54  ? -17.71326 51.02164 33.82717  1.000 49.06253  ? 54  GLY A O   1 
ATOM   3656 N N   . GLY C 1 55  ? -15.87229 51.54724 32.65082  1.000 47.48375  ? 55  GLY A N   1 
ATOM   3657 C CA  . GLY C 1 55  ? -14.97327 50.85403 33.55225  1.000 51.94554  ? 55  GLY A CA  1 
ATOM   3658 C C   . GLY C 1 55  ? -14.82769 49.36021 33.34568  1.000 53.26550  ? 55  GLY A C   1 
ATOM   3659 O O   . GLY C 1 55  ? -14.28606 48.68224 34.22969  1.000 53.88695  ? 55  GLY A O   1 
ATOM   3660 N N   . ARG C 1 56  ? -15.28471 48.81999 32.22077  1.000 38.85892  ? 56  ARG A N   1 
ATOM   3661 C CA  . ARG C 1 56  ? -15.11426 47.40486 31.93022  1.000 42.52043  ? 56  ARG A CA  1 
ATOM   3662 C C   . ARG C 1 56  ? -14.01379 47.21867 30.89323  1.000 48.78230  ? 56  ARG A C   1 
ATOM   3663 O O   . ARG C 1 56  ? -13.93440 47.96686 29.91394  1.000 43.31445  ? 56  ARG A O   1 
ATOM   3664 C CB  . ARG C 1 56  ? -16.42295 46.78189 31.43998  1.000 47.66032  ? 56  ARG A CB  1 
ATOM   3665 C CG  . ARG C 1 56  ? -17.49366 46.65810 32.52255  1.000 49.15022  ? 56  ARG A CG  1 
ATOM   3666 C CD  . ARG C 1 56  ? -18.66210 45.81107 32.04695  1.000 51.35595  ? 56  ARG A CD  1 
ATOM   3667 N NE  . ARG C 1 56  ? -19.47232 46.50492 31.05097  1.000 54.16526  ? 56  ARG A NE  1 
ATOM   3668 C CZ  . ARG C 1 56  ? -20.30036 45.90080 30.20895  1.000 58.71280  ? 56  ARG A CZ  1 
ATOM   3669 N NH1 . ARG C 1 56  ? -20.41750 44.58014 30.18081  1.000 51.47885  ? 56  ARG A NH1 1 
ATOM   3670 N NH2 . ARG C 1 56  ? -21.02527 46.63862 29.37199  1.000 48.49514  ? 56  ARG A NH2 1 
ATOM   3671 N N   . ALA C 1 57  ? -13.16430 46.21913 31.11757  1.000 43.00538  ? 57  ALA A N   1 
ATOM   3672 C CA  . ALA C 1 57  ? -11.98008 45.99576 30.29904  1.000 44.04149  ? 57  ALA A CA  1 
ATOM   3673 C C   . ALA C 1 57  ? -12.20381 44.83026 29.34658  1.000 48.33020  ? 57  ALA A C   1 
ATOM   3674 O O   . ALA C 1 57  ? -12.70067 43.77638 29.75472  1.000 41.83945  ? 57  ALA A O   1 
ATOM   3675 C CB  . ALA C 1 57  ? -10.76058 45.72428 31.17706  1.000 46.86267  ? 57  ALA A CB  1 
ATOM   3676 N N   . PHE C 1 58  ? -11.81917 45.01992 28.08551  1.000 37.12602  ? 58  PHE A N   1 
ATOM   3677 C CA  . PHE C 1 58  ? -11.87941 43.98183 27.06957  1.000 38.20992  ? 58  PHE A CA  1 
ATOM   3678 C C   . PHE C 1 58  ? -10.53495 43.91464 26.36062  1.000 44.97908  ? 58  PHE A C   1 
ATOM   3679 O O   . PHE C 1 58  ? -9.90897  44.95226 26.10956  1.000 37.98284  ? 58  PHE A O   1 
ATOM   3680 C CB  . PHE C 1 58  ? -13.00868 44.25824 26.06584  1.000 46.26805  ? 58  PHE A CB  1 
ATOM   3681 C CG  . PHE C 1 58  ? -14.37371 44.33693 26.70031  1.000 49.54493  ? 58  PHE A CG  1 
ATOM   3682 C CD1 . PHE C 1 58  ? -14.87660 45.54942 27.14743  1.000 50.69400  ? 58  PHE A CD1 1 
ATOM   3683 C CD2 . PHE C 1 58  ? -15.14600 43.19594 26.86249  1.000 46.17334  ? 58  PHE A CD2 1 
ATOM   3684 C CE1 . PHE C 1 58  ? -16.13394 45.62632 27.73669  1.000 50.20132  ? 58  PHE A CE1 1 
ATOM   3685 C CE2 . PHE C 1 58  ? -16.39887 43.26416 27.45535  1.000 55.81745  ? 58  PHE A CE2 1 
ATOM   3686 C CZ  . PHE C 1 58  ? -16.89284 44.48247 27.89465  1.000 56.35811  ? 58  PHE A CZ  1 
ATOM   3687 N N   . TYR C 1 59  ? -10.09705 42.69296 26.04062  1.000 39.62325  ? 59  TYR A N   1 
ATOM   3688 C CA  . TYR C 1 59  ? -8.74660  42.42691 25.56059  1.000 43.16441  ? 59  TYR A CA  1 
ATOM   3689 C C   . TYR C 1 59  ? -8.79461  41.75344 24.19934  1.000 40.93439  ? 59  TYR A C   1 
ATOM   3690 O O   . TYR C 1 59  ? -9.73473  41.01709 23.88994  1.000 33.79836  ? 59  TYR A O   1 
ATOM   3691 C CB  . TYR C 1 59  ? -7.95787  41.52355 26.54155  1.000 38.10240  ? 59  TYR A CB  1 
ATOM   3692 C CG  . TYR C 1 59  ? -7.95397  42.03612 27.95986  1.000 48.44812  ? 59  TYR A CG  1 
ATOM   3693 C CD1 . TYR C 1 59  ? -6.96189  42.90111 28.39969  1.000 44.42249  ? 59  TYR A CD1 1 
ATOM   3694 C CD2 . TYR C 1 59  ? -8.95236  41.67285 28.85762  1.000 45.23555  ? 59  TYR A CD2 1 
ATOM   3695 C CE1 . TYR C 1 59  ? -6.95332  43.38638 29.69403  1.000 41.93600  ? 59  TYR A CE1 1 
ATOM   3696 C CE2 . TYR C 1 59  ? -8.95387  42.15914 30.15840  1.000 45.49659  ? 59  TYR A CE2 1 
ATOM   3697 C CZ  . TYR C 1 59  ? -7.95325  43.01707 30.56546  1.000 45.06943  ? 59  TYR A CZ  1 
ATOM   3698 O OH  . TYR C 1 59  ? -7.94578  43.51018 31.84637  1.000 49.06909  ? 59  TYR A OH  1 
ATOM   3699 N N   . ALA C 1 60  ? -7.78407  42.03731 23.37676  1.000 39.97857  ? 60  ALA A N   1 
ATOM   3700 C CA  . ALA C 1 60  ? -7.55621  41.23505 22.18705  1.000 37.51199  ? 60  ALA A CA  1 
ATOM   3701 C C   . ALA C 1 60  ? -7.16101  39.82657 22.60435  1.000 41.75173  ? 60  ALA A C   1 
ATOM   3702 O O   . ALA C 1 60  ? -6.71561  39.59009 23.73227  1.000 41.03476  ? 60  ALA A O   1 
ATOM   3703 C CB  . ALA C 1 60  ? -6.47153  41.84933 21.30350  1.000 37.64941  ? 60  ALA A CB  1 
ATOM   3704 N N   . SER C 1 61  ? -7.33365  38.88312 21.67825  1.000 42.43809  ? 61  SER A N   1 
ATOM   3705 C CA  . SER C 1 61  ? -7.15518  37.47416 22.01757  1.000 46.11609  ? 61  SER A CA  1 
ATOM   3706 C C   . SER C 1 61  ? -5.71751  37.17945 22.42453  1.000 48.85743  ? 61  SER A C   1 
ATOM   3707 O O   . SER C 1 61  ? -5.47008  36.55934 23.46662  1.000 48.90834  ? 61  SER A O   1 
ATOM   3708 C CB  . SER C 1 61  ? -7.57810  36.60106 20.83895  1.000 52.90222  ? 61  SER A CB  1 
ATOM   3709 O OG  . SER C 1 61  ? -8.90818  36.91145 20.45645  1.000 54.76905  ? 61  SER A OG  1 
ATOM   3710 N N   . TRP C 1 62  ? -4.75366  37.65264 21.63093  1.000 42.71753  ? 62  TRP A N   1 
ATOM   3711 C CA  . TRP C 1 62  ? -3.34519  37.34102 21.86586  1.000 49.88642  ? 62  TRP A CA  1 
ATOM   3712 C C   . TRP C 1 62  ? -2.84029  37.84062 23.21297  1.000 47.35980  ? 62  TRP A C   1 
ATOM   3713 O O   . TRP C 1 62  ? -1.77970  37.39763 23.66495  1.000 51.03668  ? 62  TRP A O   1 
ATOM   3714 C CB  . TRP C 1 62  ? -2.48491  37.94411 20.75446  1.000 47.73529  ? 62  TRP A CB  1 
ATOM   3715 C CG  . TRP C 1 62  ? -2.47786  39.45447 20.75994  1.000 48.27777  ? 62  TRP A CG  1 
ATOM   3716 C CD1 . TRP C 1 62  ? -3.33306  40.28305 20.09045  1.000 46.26808  ? 62  TRP A CD1 1 
ATOM   3717 C CD2 . TRP C 1 62  ? -1.56725  40.30777 21.46879  1.000 48.92220  ? 62  TRP A CD2 1 
ATOM   3718 N NE1 . TRP C 1 62  ? -3.01283  41.59841 20.33755  1.000 42.18237  ? 62  TRP A NE1 1 
ATOM   3719 C CE2 . TRP C 1 62  ? -1.93459  41.64091 21.18270  1.000 49.33040  ? 62  TRP A CE2 1 
ATOM   3720 C CE3 . TRP C 1 62  ? -0.48018  40.07428 22.32104  1.000 46.39685  ? 62  TRP A CE3 1 
ATOM   3721 C CZ2 . TRP C 1 62  ? -1.24918  42.73710 21.71529  1.000 35.37686  ? 62  TRP A CZ2 1 
ATOM   3722 C CZ3 . TRP C 1 62  ? 0.19985   41.16344 22.84802  1.000 44.57750  ? 62  TRP A CZ3 1 
ATOM   3723 C CH2 . TRP C 1 62  ? -0.18975  42.47747 22.54441  1.000 43.77613  ? 62  TRP A CH2 1 
ATOM   3724 N N   . ALA C 1 63  ? -3.56607  38.75131 23.85905  1.000 43.53648  ? 63  ALA A N   1 
ATOM   3725 C CA  . ALA C 1 63  ? -3.12353  39.36527 25.09552  1.000 39.42551  ? 63  ALA A CA  1 
ATOM   3726 C C   . ALA C 1 63  ? -4.01609  39.05442 26.28073  1.000 46.22195  ? 63  ALA A C   1 
ATOM   3727 O O   . ALA C 1 63  ? -3.68261  39.45938 27.40405  1.000 41.36668  ? 63  ALA A O   1 
ATOM   3728 C CB  . ALA C 1 63  ? -3.04546  40.89383 24.93522  1.000 40.32960  ? 63  ALA A CB  1 
ATOM   3729 N N   . LYS C 1 64  ? -5.13800  38.36178 26.07038  1.000 44.88116  ? 64  LYS A N   1 
ATOM   3730 C CA  . LYS C 1 64  ? -6.11097  38.19733 27.14562  1.000 50.60373  ? 64  LYS A CA  1 
ATOM   3731 C C   . LYS C 1 64  ? -5.51721  37.44809 28.33322  1.000 39.37753  ? 64  LYS A C   1 
ATOM   3732 O O   . LYS C 1 64  ? -5.82561  37.76783 29.48932  1.000 38.98857  ? 64  LYS A O   1 
ATOM   3733 C CB  . LYS C 1 64  ? -7.35607  37.47801 26.61446  1.000 41.93820  ? 64  LYS A CB  1 
ATOM   3734 C CG  . LYS C 1 64  ? -8.49279  37.40478 27.62302  1.000 45.21588  ? 64  LYS A CG  1 
ATOM   3735 C CD  . LYS C 1 64  ? -9.80550  36.97851 26.98234  1.000 52.50524  ? 64  LYS A CD  1 
ATOM   3736 C CE  . LYS C 1 64  ? -10.93583 37.00629 28.00827  1.000 59.61023  ? 64  LYS A CE  1 
ATOM   3737 N NZ  . LYS C 1 64  ? -12.27238 36.71345 27.41650  1.000 63.48173  ? 64  LYS A NZ  1 
ATOM   3738 N N   . SER C 1 65  ? -4.63193  36.48478 28.06969  1.000 37.61200  ? 65  SER A N   1 
ATOM   3739 C CA  . SER C 1 65  ? -4.11464  35.60664 29.11150  1.000 46.89323  ? 65  SER A CA  1 
ATOM   3740 C C   . SER C 1 65  ? -3.08280  36.27780 30.00560  1.000 48.78132  ? 65  SER A C   1 
ATOM   3741 O O   . SER C 1 65  ? -2.84781  35.80215 31.12112  1.000 41.42983  ? 65  SER A O   1 
ATOM   3742 C CB  . SER C 1 65  ? -3.49996  34.35534 28.47818  1.000 43.91929  ? 65  SER A CB  1 
ATOM   3743 O OG  . SER C 1 65  ? -2.52699  34.69383 27.50125  1.000 51.20764  ? 65  SER A OG  1 
ATOM   3744 N N   . ARG C 1 66  ? -2.46615  37.36481 29.55234  1.000 44.17153  ? 66  ARG A N   1 
ATOM   3745 C CA  . ARG C 1 66  ? -1.37568  37.98465 30.28638  1.000 43.69110  ? 66  ARG A CA  1 
ATOM   3746 C C   . ARG C 1 66  ? -1.63705  39.42141 30.71249  1.000 43.77613  ? 66  ARG A C   1 
ATOM   3747 O O   . ARG C 1 66  ? -0.86462  39.95104 31.52021  1.000 47.40576  ? 66  ARG A O   1 
ATOM   3748 C CB  . ARG C 1 66  ? -0.08789  37.95025 29.44850  1.000 43.75499  ? 66  ARG A CB  1 
ATOM   3749 C CG  . ARG C 1 66  ? 0.35009   36.55724 29.02273  1.000 46.53069  ? 66  ARG A CG  1 
ATOM   3750 C CD  . ARG C 1 66  ? 1.71720   36.59489 28.34908  1.000 49.05596  ? 66  ARG A CD  1 
ATOM   3751 N NE  . ARG C 1 66  ? 1.69234   37.36073 27.10998  1.000 51.72891  ? 66  ARG A NE  1 
ATOM   3752 C CZ  . ARG C 1 66  ? 2.76097   37.90668 26.54443  1.000 54.97259  ? 66  ARG A CZ  1 
ATOM   3753 N NH1 . ARG C 1 66  ? 3.95949   37.80575 27.09196  1.000 52.64305  ? 66  ARG A NH1 1 
ATOM   3754 N NH2 . ARG C 1 66  ? 2.62205   38.57780 25.40476  1.000 49.80371  ? 66  ARG A NH2 1 
ATOM   3755 N N   . SER C 1 67  ? -2.69891  40.05937 30.22775  1.000 39.98777  ? 67  SER A N   1 
ATOM   3756 C CA  . SER C 1 67  ? -2.85317  41.49884 30.36179  1.000 32.94945  ? 67  SER A CA  1 
ATOM   3757 C C   . SER C 1 67  ? -3.99450  41.86796 31.30021  1.000 40.69059  ? 67  SER A C   1 
ATOM   3758 O O   . SER C 1 67  ? -4.98258  41.14154 31.43135  1.000 45.94075  ? 67  SER A O   1 
ATOM   3759 C CB  . SER C 1 67  ? -3.09278  42.14258 28.99686  1.000 32.84222  ? 67  SER A CB  1 
ATOM   3760 O OG  . SER C 1 67  ? -2.16444  41.64801 28.04354  1.000 35.18786  ? 67  SER A OG  1 
ATOM   3761 N N   . THR C 1 68  ? -3.84697  43.02869 31.93311  1.000 35.28118  ? 68  THR A N   1 
ATOM   3762 C CA  . THR C 1 68  ? -4.87213  43.61982 32.78078  1.000 40.92331  ? 68  THR A CA  1 
ATOM   3763 C C   . THR C 1 68  ? -4.85077  45.12918 32.58806  1.000 44.43951  ? 68  THR A C   1 
ATOM   3764 O O   . THR C 1 68  ? -3.78354  45.74824 32.64704  1.000 40.61212  ? 68  THR A O   1 
ATOM   3765 C CB  . THR C 1 68  ? -4.64580  43.27596 34.25999  1.000 39.37760  ? 68  THR A CB  1 
ATOM   3766 O OG1 . THR C 1 68  ? -4.61665  41.85132 34.42532  1.000 51.77357  ? 68  THR A OG1 1 
ATOM   3767 C CG2 . THR C 1 68  ? -5.75468  43.85572 35.11351  1.000 40.15193  ? 68  THR A CG2 1 
ATOM   3768 N N   . ILE C 1 69  ? -6.02356  45.71860 32.36086  1.000 45.49313  ? 69  ILE A N   1 
ATOM   3769 C CA  . ILE C 1 69  ? -6.17188  47.16290 32.20119  1.000 37.28354  ? 69  ILE A CA  1 
ATOM   3770 C C   . ILE C 1 69  ? -7.17265  47.65428 33.24115  1.000 46.58981  ? 69  ILE A C   1 
ATOM   3771 O O   . ILE C 1 69  ? -8.32589  47.20466 33.26214  1.000 56.38152  ? 69  ILE A O   1 
ATOM   3772 C CB  . ILE C 1 69  ? -6.62129  47.52900 30.77822  1.000 43.21343  ? 69  ILE A CB  1 
ATOM   3773 C CG1 . ILE C 1 69  ? -5.60229  47.01623 29.75554  1.000 30.35733  ? 69  ILE A CG1 1 
ATOM   3774 C CG2 . ILE C 1 69  ? -6.79819  49.02910 30.63530  1.000 35.90388  ? 69  ILE A CG2 1 
ATOM   3775 C CD1 . ILE C 1 69  ? -6.03986  47.20374 28.33009  1.000 38.25411  ? 69  ILE A CD1 1 
ATOM   3776 N N   . THR C 1 70  ? -6.73346  48.56367 34.10771  1.000 47.46184  ? 70  THR A N   1 
ATOM   3777 C CA  . THR C 1 70  ? -7.58804  49.15179 35.13191  1.000 50.44212  ? 70  THR A CA  1 
ATOM   3778 C C   . THR C 1 70  ? -7.48644  50.66982 35.06015  1.000 50.59004  ? 70  THR A C   1 
ATOM   3779 O O   . THR C 1 70  ? -6.74446  51.22553 34.24621  1.000 52.60526  ? 70  THR A O   1 
ATOM   3780 C CB  . THR C 1 70  ? -7.20483  48.66505 36.53486  1.000 54.73325  ? 70  THR A CB  1 
ATOM   3781 O OG1 . THR C 1 70  ? -5.83283  48.98791 36.79141  1.000 51.57525  ? 70  THR A OG1 1 
ATOM   3782 C CG2 . THR C 1 70  ? -7.41255  47.16652 36.66087  1.000 51.70117  ? 70  THR A CG2 1 
ATOM   3783 N N   . ARG C 1 71  ? -8.24307  51.34925 35.92235  1.000 54.22991  ? 71  ARG A N   1 
ATOM   3784 C CA  . ARG C 1 71  ? -8.08722  52.78690 36.08721  1.000 52.38741  ? 71  ARG A CA  1 
ATOM   3785 C C   . ARG C 1 71  ? -8.29093  53.17292 37.54536  1.000 55.44808  ? 71  ARG A C   1 
ATOM   3786 O O   . ARG C 1 71  ? -8.85963  52.42711 38.34679  1.000 48.27491  ? 71  ARG A O   1 
ATOM   3787 C CB  . ARG C 1 71  ? -9.03904  53.59141 35.18886  1.000 51.30324  ? 71  ARG A CB  1 
ATOM   3788 C CG  . ARG C 1 71  ? -10.50441 53.54655 35.55017  1.000 52.07572  ? 71  ARG A CG  1 
ATOM   3789 C CD  . ARG C 1 71  ? -11.18084 54.80810 35.02870  1.000 53.63143  ? 71  ARG A CD  1 
ATOM   3790 N NE  . ARG C 1 71  ? -12.63343 54.70504 34.95941  1.000 57.75297  ? 71  ARG A NE  1 
ATOM   3791 C CZ  . ARG C 1 71  ? -13.32843 54.70272 33.83070  1.000 57.58673  ? 71  ARG A CZ  1 
ATOM   3792 N NH1 . ARG C 1 71  ? -12.73157 54.77135 32.65201  1.000 63.07914  ? 71  ARG A NH1 1 
ATOM   3793 N NH2 . ARG C 1 71  ? -14.65550 54.64429 33.88646  1.000 63.25200  ? 71  ARG A NH2 1 
ATOM   3794 N N   . ASN C 1 72  ? -7.79709  54.36134 37.87221  1.000 55.27010  ? 72  ASN A N   1 
ATOM   3795 C CA  . ASN C 1 72  ? -7.88091  54.92363 39.21551  1.000 61.51582  ? 72  ASN A CA  1 
ATOM   3796 C C   . ASN C 1 72  ? -8.19338  56.40304 39.02131  1.000 63.08421  ? 72  ASN A C   1 
ATOM   3797 O O   . ASN C 1 72  ? -7.29962  57.20023 38.71890  1.000 56.63424  ? 72  ASN A O   1 
ATOM   3798 C CB  . ASN C 1 72  ? -6.58549  54.70296 39.98796  1.000 58.19918  ? 72  ASN A CB  1 
ATOM   3799 C CG  . ASN C 1 72  ? -6.69753  55.09300 41.44794  1.000 71.12656  ? 72  ASN A CG  1 
ATOM   3800 O OD1 . ASN C 1 72  ? -7.18438  56.17499 41.78458  1.000 69.49867  ? 72  ASN A OD1 1 
ATOM   3801 N ND2 . ASN C 1 72  ? -6.24732  54.20531 42.32790  1.000 74.60637  ? 72  ASN A ND2 1 
ATOM   3802 N N   . THR C 1 73  ? -9.47014  56.75599 39.17494  1.000 61.62597  ? 73  THR A N   1 
ATOM   3803 C CA  . THR C 1 73  ? -9.90848  58.11722 38.89415  1.000 57.58729  ? 73  THR A CA  1 
ATOM   3804 C C   . THR C 1 73  ? -9.37560  59.11067 39.91590  1.000 67.70022  ? 73  THR A C   1 
ATOM   3805 O O   . THR C 1 73  ? -9.16081  60.28292 39.58277  1.000 63.10571  ? 73  THR A O   1 
ATOM   3806 C CB  . THR C 1 73  ? -11.42484 58.15782 38.85583  1.000 65.78853  ? 73  THR A CB  1 
ATOM   3807 O OG1 . THR C 1 73  ? -11.91762 57.77877 40.14392  1.000 76.94017  ? 73  THR A OG1 1 
ATOM   3808 C CG2 . THR C 1 73  ? -11.93380 57.17148 37.81258  1.000 57.74874  ? 73  THR A CG2 1 
ATOM   3809 N N   . ASN C 1 74  ? -9.17130  58.67346 41.16163  1.000 68.32830  ? 74  ASN A N   1 
ATOM   3810 C CA  . ASN C 1 74  ? -8.46118  59.51523 42.11837  1.000 68.21785  ? 74  ASN A CA  1 
ATOM   3811 C C   . ASN C 1 74  ? -7.05286  59.80252 41.62783  1.000 69.38473  ? 74  ASN A C   1 
ATOM   3812 O O   . ASN C 1 74  ? -6.54167  60.91708 41.79222  1.000 70.21745  ? 74  ASN A O   1 
ATOM   3813 C CB  . ASN C 1 74  ? -8.41769  58.84404 43.48837  1.000 70.84182  ? 74  ASN A CB  1 
ATOM   3814 C CG  . ASN C 1 74  ? -9.72784  58.19616 43.85323  1.000 74.20462  ? 74  ASN A CG  1 
ATOM   3815 O OD1 . ASN C 1 74  ? -9.78307  56.99729 44.13838  1.000 72.76275  ? 74  ASN A OD1 1 
ATOM   3816 N ND2 . ASN C 1 74  ? -10.79869 58.98245 43.83773  1.000 72.86400  ? 74  ASN A ND2 1 
ATOM   3817 N N   . GLU C 1 75  ? -6.41258  58.80038 41.02116  1.000 64.49575  ? 75  GLU A N   1 
ATOM   3818 C CA  . GLU C 1 75  ? -5.13115  58.98610 40.35477  1.000 69.08963  ? 75  GLU A CA  1 
ATOM   3819 C C   . GLU C 1 75  ? -5.26699  59.69738 39.01298  1.000 57.57008  ? 75  GLU A C   1 
ATOM   3820 O O   . GLU C 1 75  ? -4.27935  60.25512 38.52211  1.000 58.81940  ? 75  GLU A O   1 
ATOM   3821 C CB  . GLU C 1 75  ? -4.45430  57.62802 40.14475  1.000 70.20928  ? 75  GLU A CB  1 
ATOM   3822 C CG  . GLU C 1 75  ? -2.95416  57.63467 40.34991  1.000 72.53209  ? 75  GLU A CG  1 
ATOM   3823 C CD  . GLU C 1 75  ? -2.57715  57.83557 41.79697  1.000 74.70597  ? 75  GLU A CD  1 
ATOM   3824 O OE1 . GLU C 1 75  ? -3.37545  57.45210 42.67710  1.000 75.97639  ? 75  GLU A OE1 1 
ATOM   3825 O OE2 . GLU C 1 75  ? -1.48613  58.38323 42.05351  1.000 85.85668  ? 75  GLU A OE2 1 
ATOM   3826 N N   . ASN C 1 76  ? -6.46608  59.70098 38.42399  1.000 57.98046  ? 76  ASN A N   1 
ATOM   3827 C CA  . ASN C 1 76  ? -6.68548  60.19274 37.06154  1.000 61.15014  ? 76  ASN A CA  1 
ATOM   3828 C C   . ASN C 1 76  ? -5.81379  59.43070 36.06209  1.000 58.52368  ? 76  ASN A C   1 
ATOM   3829 O O   . ASN C 1 76  ? -5.27884  60.00209 35.11008  1.000 60.05146  ? 76  ASN A O   1 
ATOM   3830 C CB  . ASN C 1 76  ? -6.44539  61.70423 36.95805  1.000 56.28582  ? 76  ASN A CB  1 
ATOM   3831 C CG  . ASN C 1 76  ? -7.31662  62.36537 35.90062  1.000 58.44864  ? 76  ASN A CG  1 
ATOM   3832 O OD1 . ASN C 1 76  ? -8.43155  61.91668 35.62809  1.000 65.00944  ? 76  ASN A OD1 1 
ATOM   3833 N ND2 . ASN C 1 76  ? -6.81079  63.43856 35.29993  1.000 61.15620  ? 76  ASN A ND2 1 
ATOM   3834 N N   . THR C 1 77  ? -5.67557  58.12441 36.27397  1.000 53.49292  ? 77  THR A N   1 
ATOM   3835 C CA  . THR C 1 77  ? -4.78650  57.30192 35.47057  1.000 56.97452  ? 77  THR A CA  1 
ATOM   3836 C C   . THR C 1 77  ? -5.51700  56.07788 34.94448  1.000 51.93513  ? 77  THR A C   1 
ATOM   3837 O O   . THR C 1 77  ? -6.53162  55.64417 35.49328  1.000 53.05222  ? 77  THR A O   1 
ATOM   3838 C CB  . THR C 1 77  ? -3.56240  56.82781 36.25898  1.000 54.08843  ? 77  THR A CB  1 
ATOM   3839 O OG1 . THR C 1 77  ? -3.99515  55.99647 37.33945  1.000 59.18522  ? 77  THR A OG1 1 
ATOM   3840 C CG2 . THR C 1 77  ? -2.77116  58.00768 36.80066  1.000 55.92046  ? 77  THR A CG2 1 
ATOM   3841 N N   . VAL C 1 78  ? -4.97956  55.53488 33.85515  1.000 50.92758  ? 78  VAL A N   1 
ATOM   3842 C CA  . VAL C 1 78  ? -5.29395  54.19358 33.38411  1.000 46.46229  ? 78  VAL A CA  1 
ATOM   3843 C C   . VAL C 1 78  ? -3.98349  53.41551 33.35547  1.000 47.83363  ? 78  VAL A C   1 
ATOM   3844 O O   . VAL C 1 78  ? -2.91835  53.98975 33.10492  1.000 42.60019  ? 78  VAL A O   1 
ATOM   3845 C CB  . VAL C 1 78  ? -5.98896  54.21665 32.00145  1.000 52.91024  ? 78  VAL A CB  1 
ATOM   3846 C CG1 . VAL C 1 78  ? -5.15627  54.98153 30.97255  1.000 51.11283  ? 78  VAL A CG1 1 
ATOM   3847 C CG2 . VAL C 1 78  ? -6.30151  52.80917 31.51811  1.000 44.13254  ? 78  VAL A CG2 1 
ATOM   3848 N N   . THR C 1 79  ? -4.04797  52.12370 33.65304  1.000 46.24235  ? 79  THR A N   1 
ATOM   3849 C CA  . THR C 1 79  ? -2.84050  51.33469 33.85098  1.000 46.89879  ? 79  THR A CA  1 
ATOM   3850 C C   . THR C 1 79  ? -2.92339  50.03638 33.05999  1.000 42.81242  ? 79  THR A C   1 
ATOM   3851 O O   . THR C 1 79  ? -3.99406  49.43136 32.94810  1.000 40.69607  ? 79  THR A O   1 
ATOM   3852 C CB  . THR C 1 79  ? -2.61725  51.06280 35.36069  1.000 53.04101  ? 79  THR A CB  1 
ATOM   3853 O OG1 . THR C 1 79  ? -2.23270  52.28586 36.00968  1.000 53.51159  ? 79  THR A OG1 1 
ATOM   3854 C CG2 . THR C 1 79  ? -1.53419  50.01174 35.60082  1.000 42.77708  ? 79  THR A CG2 1 
ATOM   3855 N N   . LEU C 1 80  ? -1.79403  49.63488 32.47793  1.000 40.72465  ? 80  LEU A N   1 
ATOM   3856 C CA  . LEU C 1 80  ? -1.65587  48.34467 31.81884  1.000 38.78610  ? 80  LEU A CA  1 
ATOM   3857 C C   . LEU C 1 80  ? -0.62990  47.50725 32.56547  1.000 37.51497  ? 80  LEU A C   1 
ATOM   3858 O O   . LEU C 1 80  ? 0.45580   47.99807 32.88818  1.000 36.73847  ? 80  LEU A O   1 
ATOM   3859 C CB  . LEU C 1 80  ? -1.22145  48.50412 30.36203  1.000 38.35356  ? 80  LEU A CB  1 
ATOM   3860 C CG  . LEU C 1 80  ? -0.80085  47.22178 29.63706  1.000 37.73665  ? 80  LEU A CG  1 
ATOM   3861 C CD1 . LEU C 1 80  ? -1.98631  46.29733 29.44868  1.000 32.43058  ? 80  LEU A CD1 1 
ATOM   3862 C CD2 . LEU C 1 80  ? -0.15373  47.55147 28.28273  1.000 28.54944  ? 80  LEU A CD2 1 
ATOM   3863 N N   . LYS C 1 81  ? -0.97694  46.24897 32.83220  1.000 37.03385  ? 81  LYS A N   1 
ATOM   3864 C CA  . LYS C 1 81  ? -0.05681  45.24853 33.36291  1.000 36.63272  ? 81  LYS A CA  1 
ATOM   3865 C C   . LYS C 1 81  ? -0.03232  44.05353 32.42142  1.000 37.07781  ? 81  LYS A C   1 
ATOM   3866 O O   . LYS C 1 81  ? -1.08731  43.59448 31.96708  1.000 34.06363  ? 81  LYS A O   1 
ATOM   3867 C CB  . LYS C 1 81  ? -0.46265  44.78678 34.77071  1.000 36.85555  ? 81  LYS A CB  1 
ATOM   3868 C CG  . LYS C 1 81  ? -0.24733  45.82575 35.86815  1.000 43.96825  ? 81  LYS A CG  1 
ATOM   3869 C CD  . LYS C 1 81  ? -0.50287  45.24581 37.25873  1.000 46.62226  ? 81  LYS A CD  1 
ATOM   3870 C CE  . LYS C 1 81  ? -0.21154  46.27794 38.34366  1.000 53.25811  ? 81  LYS A CE  1 
ATOM   3871 N NZ  . LYS C 1 81  ? -0.42654  45.73390 39.71749  1.000 58.08121  ? 81  LYS A NZ  1 
ATOM   3872 N N   . MET C 1 82  ? 1.16687   43.55076 32.13180  1.000 31.52801  ? 82  MET A N   1 
ATOM   3873 C CA  . MET C 1 82  ? 1.34068   42.35102 31.32305  1.000 31.30406  ? 82  MET A CA  1 
ATOM   3874 C C   . MET C 1 82  ? 2.43187   41.49608 31.94555  1.000 39.86392  ? 82  MET A C   1 
ATOM   3875 O O   . MET C 1 82  ? 3.47582   42.01883 32.33933  1.000 41.97073  ? 82  MET A O   1 
ATOM   3876 C CB  . MET C 1 82  ? 1.72192   42.68153 29.87184  1.000 37.94828  ? 82  MET A CB  1 
ATOM   3877 C CG  . MET C 1 82  ? 0.61900   43.31459 29.05397  1.000 45.95735  ? 82  MET A CG  1 
ATOM   3878 S SD  . MET C 1 82  ? 1.06477   43.62164 27.32897  1.000 49.55416  ? 82  MET A SD  1 
ATOM   3879 C CE  . MET C 1 82  ? 1.75786   42.03748 26.83765  1.000 30.44185  ? 82  MET A CE  1 
ATOM   3880 N N   . ASN C 1 83  A 2.20314   40.19012 32.03211  1.000 40.49062  ? 82  ASN A N   1 
ATOM   3881 C CA  . ASN C 1 83  A 3.18064   39.29031 32.63831  1.000 38.41721  ? 82  ASN A CA  1 
ATOM   3882 C C   . ASN C 1 83  A 3.68694   38.29795 31.59654  1.000 41.00689  ? 82  ASN A C   1 
ATOM   3883 O O   . ASN C 1 83  A 3.26909   38.31832 30.43471  1.000 42.52086  ? 82  ASN A O   1 
ATOM   3884 C CB  . ASN C 1 83  A 2.59181   38.58090 33.86761  1.000 49.28517  ? 82  ASN A CB  1 
ATOM   3885 C CG  . ASN C 1 83  A 1.27979   37.85539 33.57313  1.000 59.13422  ? 82  ASN A CG  1 
ATOM   3886 O OD1 . ASN C 1 83  A 1.14901   37.14627 32.57097  1.000 53.82343  ? 82  ASN A OD1 1 
ATOM   3887 N ND2 . ASN C 1 83  A 0.30184   38.03036 34.45751  1.000 65.41412  ? 82  ASN A ND2 1 
ATOM   3888 N N   . SER C 1 84  B 4.62031   37.44470 32.02735  1.000 43.34910  ? 82  SER A N   1 
ATOM   3889 C CA  . SER C 1 84  B 5.18622   36.38531 31.19264  1.000 40.36800  ? 82  SER A CA  1 
ATOM   3890 C C   . SER C 1 84  B 5.72012   36.95249 29.88209  1.000 41.42700  ? 82  SER A C   1 
ATOM   3891 O O   . SER C 1 84  B 5.44381   36.45000 28.79088  1.000 42.75149  ? 82  SER A O   1 
ATOM   3892 C CB  . SER C 1 84  B 4.15729   35.28608 30.93863  1.000 51.54899  ? 82  SER A CB  1 
ATOM   3893 O OG  . SER C 1 84  B 3.73634   34.71601 32.16236  1.000 58.46617  ? 82  SER A OG  1 
ATOM   3894 N N   . LEU C 1 85  C 6.49521   38.02269 30.00616  1.000 48.28251  ? 82  LEU A N   1 
ATOM   3895 C CA  . LEU C 1 85  C 6.98037   38.76035 28.85270  1.000 39.66203  ? 82  LEU A CA  1 
ATOM   3896 C C   . LEU C 1 85  C 8.09337   37.99872 28.14848  1.000 36.84045  ? 82  LEU A C   1 
ATOM   3897 O O   . LEU C 1 85  C 8.88131   37.28482 28.77041  1.000 32.87341  ? 82  LEU A O   1 
ATOM   3898 C CB  . LEU C 1 85  C 7.47935   40.14245 29.28043  1.000 34.51814  ? 82  LEU A CB  1 
ATOM   3899 C CG  . LEU C 1 85  C 6.39627   41.10194 29.79442  1.000 35.88114  ? 82  LEU A CG  1 
ATOM   3900 C CD1 . LEU C 1 85  C 7.00008   42.43235 30.21478  1.000 34.50435  ? 82  LEU A CD1 1 
ATOM   3901 C CD2 . LEU C 1 85  C 5.34383   41.31732 28.73303  1.000 37.14061  ? 82  LEU A CD2 1 
ATOM   3902 N N   . ARG C 1 86  ? 8.13968   38.14973 26.82979  1.000 35.18435  ? 83  ARG A N   1 
ATOM   3903 C CA  . ARG C 1 86  ? 9.20914   37.60879 26.01208  1.000 36.81129  ? 83  ARG A CA  1 
ATOM   3904 C C   . ARG C 1 86  ? 9.80646   38.73821 25.18579  1.000 33.50737  ? 83  ARG A C   1 
ATOM   3905 O O   . ARG C 1 86  ? 9.24489   39.83283 25.09581  1.000 31.08632  ? 83  ARG A O   1 
ATOM   3906 C CB  . ARG C 1 86  ? 8.71336   36.48655 25.08842  1.000 41.18220  ? 83  ARG A CB  1 
ATOM   3907 C CG  . ARG C 1 86  ? 8.24316   35.22539 25.79602  1.000 50.01288  ? 83  ARG A CG  1 
ATOM   3908 C CD  . ARG C 1 86  ? 6.74078   35.24411 26.03958  1.000 52.83452  ? 83  ARG A CD  1 
ATOM   3909 N NE  . ARG C 1 86  ? 6.02000   35.95649 24.98880  1.000 61.90067  ? 83  ARG A NE  1 
ATOM   3910 C CZ  . ARG C 1 86  ? 4.76749   35.70177 24.63265  1.000 65.31070  ? 83  ARG A CZ  1 
ATOM   3911 N NH1 . ARG C 1 86  ? 4.08335   34.70694 25.17658  1.000 65.80027  ? 83  ARG A NH1 1 
ATOM   3912 N NH2 . ARG C 1 86  ? 4.18951   36.45999 23.70372  1.000 58.98828  ? 83  ARG A NH2 1 
ATOM   3913 N N   . ALA C 1 87  ? 10.95019  38.44105 24.56200  1.000 31.21616  ? 84  ALA A N   1 
ATOM   3914 C CA  . ALA C 1 87  ? 11.63734  39.40603 23.70608  1.000 41.57872  ? 84  ALA A CA  1 
ATOM   3915 C C   . ALA C 1 87  ? 10.71059  40.06687 22.68581  1.000 43.79655  ? 84  ALA A C   1 
ATOM   3916 O O   . ALA C 1 87  ? 10.88221  41.25221 22.37151  1.000 42.41395  ? 84  ALA A O   1 
ATOM   3917 C CB  . ALA C 1 87  ? 12.79722  38.71280 22.98783  1.000 35.80433  ? 84  ALA A CB  1 
ATOM   3918 N N   . GLU C 1 88  ? 9.72954   39.32461 22.15322  1.000 41.02537  ? 85  GLU A N   1 
ATOM   3919 C CA  . GLU C 1 88  ? 8.82038   39.88126 21.14921  1.000 33.46037  ? 85  GLU A CA  1 
ATOM   3920 C C   . GLU C 1 88  ? 7.89477   40.94476 21.72464  1.000 34.20174  ? 85  GLU A C   1 
ATOM   3921 O O   . GLU C 1 88  ? 7.26454   41.68136 20.95489  1.000 38.67231  ? 85  GLU A O   1 
ATOM   3922 C CB  . GLU C 1 88  ? 7.95912   38.78626 20.51027  1.000 46.40896  ? 85  GLU A CB  1 
ATOM   3923 C CG  . GLU C 1 88  ? 8.71005   37.55436 20.05009  1.000 48.84903  ? 85  GLU A CG  1 
ATOM   3924 C CD  . GLU C 1 88  ? 9.02816   36.60647 21.19540  1.000 64.65376  ? 85  GLU A CD  1 
ATOM   3925 O OE1 . GLU C 1 88  ? 8.08064   36.08871 21.83507  1.000 69.19648  ? 85  GLU A OE1 1 
ATOM   3926 O OE2 . GLU C 1 88  ? 10.23044  36.39867 21.46776  1.000 56.12940  ? 85  GLU A OE2 1 
ATOM   3927 N N   . ASP C 1 89  ? 7.77463   41.02372 23.04934  1.000 27.89377  ? 86  ASP A N   1 
ATOM   3928 C CA  . ASP C 1 89  ? 6.98648   42.07517 23.67990  1.000 33.39224  ? 86  ASP A CA  1 
ATOM   3929 C C   . ASP C 1 89  ? 7.73563   43.39758 23.75269  1.000 30.84132  ? 86  ASP A C   1 
ATOM   3930 O O   . ASP C 1 89  ? 7.15216   44.39628 24.19272  1.000 31.64796  ? 86  ASP A O   1 
ATOM   3931 C CB  . ASP C 1 89  ? 6.55702   41.64024 25.08447  1.000 30.60478  ? 86  ASP A CB  1 
ATOM   3932 C CG  . ASP C 1 89  ? 5.66957   40.39069 25.06894  1.000 38.10021  ? 86  ASP A CG  1 
ATOM   3933 O OD1 . ASP C 1 89  ? 4.68341   40.35915 24.30757  1.000 37.35689  ? 86  ASP A OD1 1 
ATOM   3934 O OD2 . ASP C 1 89  ? 5.96930   39.43726 25.81402  1.000 40.56200  ? 86  ASP A OD2 1 
ATOM   3935 N N   . THR C 1 90  ? 9.00528   43.41643 23.34033  1.000 30.19858  ? 87  THR A N   1 
ATOM   3936 C CA  . THR C 1 90  ? 9.76601   44.65565 23.22530  1.000 27.64403  ? 87  THR A CA  1 
ATOM   3937 C C   . THR C 1 90  ? 9.10369   45.58846 22.21746  1.000 27.84927  ? 87  THR A C   1 
ATOM   3938 O O   . THR C 1 90  ? 8.99978   45.26278 21.02917  1.000 29.27923  ? 87  THR A O   1 
ATOM   3939 C CB  . THR C 1 90  ? 11.20280  44.33416 22.80608  1.000 30.35100  ? 87  THR A CB  1 
ATOM   3940 O OG1 . THR C 1 90  ? 11.84508  43.56618 23.83910  1.000 26.28199  ? 87  THR A OG1 1 
ATOM   3941 C CG2 . THR C 1 90  ? 11.99924  45.60935 22.54126  1.000 30.72700  ? 87  THR A CG2 1 
ATOM   3942 N N   . ALA C 1 91  ? 8.66226   46.75148 22.68726  1.000 28.20266  ? 88  ALA A N   1 
ATOM   3943 C CA  . ALA C 1 91  ? 7.89505   47.65282 21.83855  1.000 27.44368  ? 88  ALA A CA  1 
ATOM   3944 C C   . ALA C 1 91  ? 7.71424   48.98080 22.55044  1.000 30.07349  ? 88  ALA A C   1 
ATOM   3945 O O   . ALA C 1 91  ? 7.93476   49.10461 23.76059  1.000 30.61790  ? 88  ALA A O   1 
ATOM   3946 C CB  . ALA C 1 91  ? 6.52518   47.07010 21.47565  1.000 28.86908  ? 88  ALA A CB  1 
ATOM   3947 N N   . VAL C 1 92  ? 7.29505   49.97021 21.77344  1.000 23.74812  ? 89  VAL A N   1 
ATOM   3948 C CA  . VAL C 1 92  ? 6.80698   51.23272 22.30470  1.000 25.38124  ? 89  VAL A CA  1 
ATOM   3949 C C   . VAL C 1 92  ? 5.32270   51.06175 22.59760  1.000 31.01305  ? 89  VAL A C   1 
ATOM   3950 O O   . VAL C 1 92  ? 4.53942   50.72859 21.69994  1.000 28.04666  ? 89  VAL A O   1 
ATOM   3951 C CB  . VAL C 1 92  ? 7.03954   52.37818 21.31208  1.000 29.01837  ? 89  VAL A CB  1 
ATOM   3952 C CG1 . VAL C 1 92  ? 6.49372   53.67361 21.87901  1.000 29.46971  ? 89  VAL A CG1 1 
ATOM   3953 C CG2 . VAL C 1 92  ? 8.51830   52.49240 20.97325  1.000 33.78404  ? 89  VAL A CG2 1 
ATOM   3954 N N   . TYR C 1 93  ? 4.93120   51.27616 23.84900  1.000 23.61862  ? 90  TYR A N   1 
ATOM   3955 C CA  . TYR C 1 93  ? 3.53924   51.12825 24.24547  1.000 28.28263  ? 90  TYR A CA  1 
ATOM   3956 C C   . TYR C 1 93  ? 2.88535   52.49617 24.30873  1.000 30.94059  ? 90  TYR A C   1 
ATOM   3957 O O   . TYR C 1 93  ? 3.52354   53.48228 24.68604  1.000 32.12933  ? 90  TYR A O   1 
ATOM   3958 C CB  . TYR C 1 93  ? 3.42135   50.41204 25.59443  1.000 29.07269  ? 90  TYR A CB  1 
ATOM   3959 C CG  . TYR C 1 93  ? 3.77741   48.94417 25.50333  1.000 28.39177  ? 90  TYR A CG  1 
ATOM   3960 C CD1 . TYR C 1 93  ? 5.08594   48.54395 25.25462  1.000 32.29518  ? 90  TYR A CD1 1 
ATOM   3961 C CD2 . TYR C 1 93  ? 2.79899   47.95917 25.63863  1.000 27.94850  ? 90  TYR A CD2 1 
ATOM   3962 C CE1 . TYR C 1 93  ? 5.41729   47.20295 25.14238  1.000 29.75605  ? 90  TYR A CE1 1 
ATOM   3963 C CE2 . TYR C 1 93  ? 3.12032   46.60756 25.53476  1.000 29.51635  ? 90  TYR A CE2 1 
ATOM   3964 C CZ  . TYR C 1 93  ? 4.43267   46.24005 25.28969  1.000 26.16252  ? 90  TYR A CZ  1 
ATOM   3965 O OH  . TYR C 1 93  ? 4.77705   44.91541 25.16622  1.000 29.06078  ? 90  TYR A OH  1 
ATOM   3966 N N   . TYR C 1 94  ? 1.61539   52.55137 23.91572  1.000 32.91643  ? 91  TYR A N   1 
ATOM   3967 C CA  . TYR C 1 94  ? 0.84433   53.78431 23.89077  1.000 32.45205  ? 91  TYR A CA  1 
ATOM   3968 C C   . TYR C 1 94  ? -0.47989  53.55844 24.59881  1.000 35.91046  ? 91  TYR A C   1 
ATOM   3969 O O   . TYR C 1 94  ? -1.07897  52.49035 24.47319  1.000 33.42368  ? 91  TYR A O   1 
ATOM   3970 C CB  . TYR C 1 94  ? 0.53251   54.25769 22.45593  1.000 30.96284  ? 91  TYR A CB  1 
ATOM   3971 C CG  . TYR C 1 94  ? 1.69038   54.56443 21.52849  1.000 33.54073  ? 91  TYR A CG  1 
ATOM   3972 C CD1 . TYR C 1 94  ? 2.23606   53.57531 20.71195  1.000 36.02754  ? 91  TYR A CD1 1 
ATOM   3973 C CD2 . TYR C 1 94  ? 2.17978   55.86242 21.40419  1.000 33.19224  ? 91  TYR A CD2 1 
ATOM   3974 C CE1 . TYR C 1 94  ? 3.27254   53.85978 19.83183  1.000 33.63710  ? 91  TYR A CE1 1 
ATOM   3975 C CE2 . TYR C 1 94  ? 3.22029   56.16229 20.52833  1.000 37.61096  ? 91  TYR A CE2 1 
ATOM   3976 C CZ  . TYR C 1 94  ? 3.75710   55.15860 19.74566  1.000 37.92329  ? 91  TYR A CZ  1 
ATOM   3977 O OH  . TYR C 1 94  ? 4.77875   55.44318 18.87865  1.000 36.42583  ? 91  TYR A OH  1 
ATOM   3978 N N   . CYS C 1 95  ? -0.94621  54.56671 25.32350  1.000 38.18531  ? 92  CYS A N   1 
ATOM   3979 C CA  . CYS C 1 95  ? -2.34830  54.64964 25.70278  1.000 38.19962  ? 92  CYS A CA  1 
ATOM   3980 C C   . CYS C 1 95  ? -3.03086  55.62780 24.75534  1.000 39.81307  ? 92  CYS A C   1 
ATOM   3981 O O   . CYS C 1 95  ? -2.43745  56.63954 24.37025  1.000 40.03481  ? 92  CYS A O   1 
ATOM   3982 C CB  . CYS C 1 95  ? -2.49864  55.10970 27.14835  1.000 38.93363  ? 92  CYS A CB  1 
ATOM   3983 S SG  . CYS C 1 95  ? -1.97984  56.80863 27.36841  0.485 44.47301  ? 92  CYS A SG  1 
ATOM   3984 N N   . ALA C 1 96  ? -4.27095  55.32416 24.36526  1.000 29.56751  ? 93  ALA A N   1 
ATOM   3985 C CA  . ALA C 1 96  ? -4.94113  56.15502 23.37017  1.000 35.09717  ? 93  ALA A CA  1 
ATOM   3986 C C   . ALA C 1 96  ? -6.45099  56.03403 23.48924  1.000 35.42802  ? 93  ALA A C   1 
ATOM   3987 O O   . ALA C 1 96  ? -6.97695  54.92416 23.59704  1.000 38.62544  ? 93  ALA A O   1 
ATOM   3988 C CB  . ALA C 1 96  ? -4.51228  55.75817 21.94865  1.000 31.50509  ? 93  ALA A CB  1 
ATOM   3989 N N   . LYS C 1 97  ? -7.14392  57.17034 23.45823  1.000 37.27456  ? 94  LYS A N   1 
ATOM   3990 C CA  . LYS C 1 97  ? -8.51667  57.16808 22.97295  1.000 37.46378  ? 94  LYS A CA  1 
ATOM   3991 C C   . LYS C 1 97  ? -8.43160  57.25731 21.45327  1.000 44.68957  ? 94  LYS A C   1 
ATOM   3992 O O   . LYS C 1 97  ? -8.06956  58.30441 20.90443  1.000 38.68126  ? 94  LYS A O   1 
ATOM   3993 C CB  . LYS C 1 97  ? -9.33688  58.31220 23.56039  1.000 35.01742  ? 94  LYS A CB  1 
ATOM   3994 C CG  . LYS C 1 97  ? -10.73431 58.39255 22.96532  1.000 41.19458  ? 94  LYS A CG  1 
ATOM   3995 C CD  . LYS C 1 97  ? -11.50387 59.59915 23.45369  1.000 48.50589  ? 94  LYS A CD  1 
ATOM   3996 C CE  . LYS C 1 97  ? -12.96680 59.49078 23.05543  1.000 49.12921  ? 94  LYS A CE  1 
ATOM   3997 N NZ  . LYS C 1 97  ? -13.12783 59.37239 21.57861  1.000 45.17627  ? 94  LYS A NZ  1 
ATOM   3998 N N   . LEU C 1 98  ? -8.74594  56.15231 20.77510  1.000 37.68844  ? 95  LEU A N   1 
ATOM   3999 C CA  . LEU C 1 98  ? -8.41607  56.02090 19.36454  1.000 34.92996  ? 95  LEU A CA  1 
ATOM   4000 C C   . LEU C 1 98  ? -9.26774  56.90390 18.45439  1.000 44.94894  ? 95  LEU A C   1 
ATOM   4001 O O   . LEU C 1 98  ? -8.82791  57.22564 17.34668  1.000 36.50907  ? 95  LEU A O   1 
ATOM   4002 C CB  . LEU C 1 98  ? -8.54538  54.55831 18.95493  1.000 32.33005  ? 95  LEU A CB  1 
ATOM   4003 C CG  . LEU C 1 98  ? -7.43808  53.65674 19.50027  1.000 37.56611  ? 95  LEU A CG  1 
ATOM   4004 C CD1 . LEU C 1 98  ? -7.62529  52.21990 19.04575  1.000 33.58963  ? 95  LEU A CD1 1 
ATOM   4005 C CD2 . LEU C 1 98  ? -6.08869  54.18386 19.03551  1.000 36.25152  ? 95  LEU A CD2 1 
ATOM   4006 N N   . GLY C 1 99  ? -10.46707 57.29374 18.87599  1.000 37.27660  ? 96  GLY A N   1 
ATOM   4007 C CA  . GLY C 1 99  ? -11.29332 58.14171 18.02918  1.000 43.79396  ? 96  GLY A CA  1 
ATOM   4008 C C   . GLY C 1 99  ? -11.70822 57.49577 16.72305  1.000 41.10157  ? 96  GLY A C   1 
ATOM   4009 O O   . GLY C 1 99  ? -11.71641 58.15751 15.67718  1.000 42.15675  ? 96  GLY A O   1 
ATOM   4010 N N   . SER C 1 100 ? -12.07000 56.21307 16.76776  1.000 31.95863  ? 97  SER A N   1 
ATOM   4011 C CA  . SER C 1 100 ? -12.48666 55.48525 15.57442  1.000 37.02120  ? 97  SER A CA  1 
ATOM   4012 C C   . SER C 1 100 ? -13.75146 56.06648 14.95003  1.000 47.91154  ? 97  SER A C   1 
ATOM   4013 O O   . SER C 1 100 ? -13.92529 56.00172 13.72520  1.000 41.59086  ? 97  SER A O   1 
ATOM   4014 C CB  . SER C 1 100 ? -12.71879 54.01947 15.93542  1.000 45.09549  ? 97  SER A CB  1 
ATOM   4015 O OG  . SER C 1 100 ? -13.61020 53.92009 17.04372  1.000 38.36688  ? 97  SER A OG  1 
ATOM   4016 N N   . GLY C 1 101 ? -14.65459 56.61186 15.76476  1.000 45.65017  ? 98  GLY A N   1 
ATOM   4017 C CA  . GLY C 1 101 ? -15.92914 57.07512 15.24728  1.000 44.18272  ? 98  GLY A CA  1 
ATOM   4018 C C   . GLY C 1 101 ? -16.40657 58.37705 15.85717  1.000 48.53847  ? 98  GLY A C   1 
ATOM   4019 O O   . GLY C 1 101 ? -17.52842 58.81980 15.59517  1.000 48.16785  ? 98  GLY A O   1 
ATOM   4020 N N   . ASN C 1 102 ? -15.55984 59.00568 16.66168  1.000 47.05882  ? 99  ASN A N   1 
ATOM   4021 C CA  . ASN C 1 102 ? -15.92412 60.21683 17.37139  1.000 52.46365  ? 99  ASN A CA  1 
ATOM   4022 C C   . ASN C 1 102 ? -14.84800 61.27442 17.17445  1.000 50.94968  ? 99  ASN A C   1 
ATOM   4023 O O   . ASN C 1 102 ? -13.68739 60.94267 16.91575  1.000 45.27905  ? 99  ASN A O   1 
ATOM   4024 C CB  . ASN C 1 102 ? -16.12623 59.91817 18.86592  1.000 42.84507  ? 99  ASN A CB  1 
ATOM   4025 C CG  . ASN C 1 102 ? -17.23380 58.89413 19.10501  1.000 58.28726  ? 99  ASN A CG  1 
ATOM   4026 O OD1 . ASN C 1 102 ? -18.41739 59.23733 19.13270  1.000 55.79755  ? 99  ASN A OD1 1 
ATOM   4027 N ND2 . ASN C 1 102 ? -16.85267 57.62890 19.26407  1.000 48.46819  ? 99  ASN A ND2 1 
ATOM   4028 N N   . PRO C 1 103 ? -15.20414 62.55920 17.28425  1.000 55.37157  ? 100 PRO A N   1 
ATOM   4029 C CA  . PRO C 1 103 ? -14.22198 63.61631 16.98536  1.000 48.56530  ? 100 PRO A CA  1 
ATOM   4030 C C   . PRO C 1 103 ? -13.07988 63.71756 17.98911  1.000 50.18493  ? 100 PRO A C   1 
ATOM   4031 O O   . PRO C 1 103 ? -12.03209 64.27947 17.64820  1.000 53.11834  ? 100 PRO A O   1 
ATOM   4032 C CB  . PRO C 1 103 ? -15.07326 64.89347 16.98132  1.000 57.33728  ? 100 PRO A CB  1 
ATOM   4033 C CG  . PRO C 1 103 ? -16.24530 64.56705 17.85271  1.000 53.92669  ? 100 PRO A CG  1 
ATOM   4034 C CD  . PRO C 1 103 ? -16.52686 63.11263 17.63202  1.000 50.56215  ? 100 PRO A CD  1 
ATOM   4035 N N   . VAL C 1 104 A -13.22939 63.20187 19.20320  1.000 48.47673  ? 100 VAL A N   1 
ATOM   4036 C CA  . VAL C 1 104 A -12.19026 63.32736 20.22031  1.000 46.42954  ? 100 VAL A CA  1 
ATOM   4037 C C   . VAL C 1 104 A -11.24305 62.13660 20.11767  1.000 49.63987  ? 100 VAL A C   1 
ATOM   4038 O O   . VAL C 1 104 A -11.66392 60.98095 20.24305  1.000 42.43962  ? 100 VAL A O   1 
ATOM   4039 C CB  . VAL C 1 104 A -12.79963 63.42861 21.62556  1.000 55.04902  ? 100 VAL A CB  1 
ATOM   4040 C CG1 . VAL C 1 104 A -13.02422 64.88735 21.99811  1.000 48.50268  ? 100 VAL A CG1 1 
ATOM   4041 C CG2 . VAL C 1 104 A -14.11260 62.65495 21.68102  1.000 54.55750  ? 100 VAL A CG2 1 
ATOM   4042 N N   . ALA C 1 105 ? -9.96314  62.41904 19.89078  1.000 41.63789  ? 101 ALA A N   1 
ATOM   4043 C CA  . ALA C 1 105 ? -8.92862  61.39884 19.90520  1.000 41.67521  ? 101 ALA A CA  1 
ATOM   4044 C C   . ALA C 1 105 ? -7.72082  61.94667 20.64765  1.000 46.61082  ? 101 ALA A C   1 
ATOM   4045 O O   . ALA C 1 105 ? -7.34545  63.10887 20.46533  1.000 52.67655  ? 101 ALA A O   1 
ATOM   4046 C CB  . ALA C 1 105 ? -8.54343  60.96142 18.48691  1.000 41.74555  ? 101 ALA A CB  1 
ATOM   4047 N N   . ILE C 1 106 ? -7.12149  61.11212 21.49554  1.000 47.17034  ? 102 ILE A N   1 
ATOM   4048 C CA  . ILE C 1 106 ? -6.01577  61.53310 22.34823  1.000 45.88005  ? 102 ILE A CA  1 
ATOM   4049 C C   . ILE C 1 106 ? -5.02739  60.37894 22.46616  1.000 44.19032  ? 102 ILE A C   1 
ATOM   4050 O O   . ILE C 1 106 ? -5.42129  59.23295 22.71110  1.000 39.24227  ? 102 ILE A O   1 
ATOM   4051 C CB  . ILE C 1 106 ? -6.50964  62.00109 23.73755  1.000 45.95963  ? 102 ILE A CB  1 
ATOM   4052 C CG1 . ILE C 1 106 ? -5.34153  62.38440 24.64086  1.000 51.58528  ? 102 ILE A CG1 1 
ATOM   4053 C CG2 . ILE C 1 106 ? -7.35852  60.95430 24.40135  1.000 50.35561  ? 102 ILE A CG2 1 
ATOM   4054 C CD1 . ILE C 1 106 ? -4.82972  63.77894 24.39719  1.000 64.78271  ? 102 ILE A CD1 1 
ATOM   4055 N N   . TRP C 1 107 ? -3.74731  60.67988 22.26699  1.000 39.68570  ? 103 TRP A N   1 
ATOM   4056 C CA  . TRP C 1 107 ? -2.67976  59.69422 22.31808  1.000 42.69085  ? 103 TRP A CA  1 
ATOM   4057 C C   . TRP C 1 107 ? -1.63216  60.12441 23.32447  1.000 42.29599  ? 103 TRP A C   1 
ATOM   4058 O O   . TRP C 1 107 ? -1.33166  61.31295 23.44706  1.000 44.19303  ? 103 TRP A O   1 
ATOM   4059 C CB  . TRP C 1 107 ? -2.01072  59.51552 20.95630  1.000 32.38838  ? 103 TRP A CB  1 
ATOM   4060 C CG  . TRP C 1 107 ? -2.73261  58.58369 20.06355  1.000 39.26652  ? 103 TRP A CG  1 
ATOM   4061 C CD1 . TRP C 1 107 ? -3.99834  58.73013 19.57870  1.000 41.51674  ? 103 TRP A CD1 1 
ATOM   4062 C CD2 . TRP C 1 107 ? -2.23347  57.35119 19.52535  1.000 35.78708  ? 103 TRP A CD2 1 
ATOM   4063 N NE1 . TRP C 1 107 ? -4.32119  57.65899 18.77709  1.000 35.89406  ? 103 TRP A NE1 1 
ATOM   4064 C CE2 . TRP C 1 107 ? -3.25285  56.80171 18.72677  1.000 28.29919  ? 103 TRP A CE2 1 
ATOM   4065 C CE3 . TRP C 1 107 ? -1.02440  56.65881 19.64586  1.000 30.70971  ? 103 TRP A CE3 1 
ATOM   4066 C CZ2 . TRP C 1 107 ? -3.10014  55.59300 18.04709  1.000 28.03144  ? 103 TRP A CZ2 1 
ATOM   4067 C CZ3 . TRP C 1 107 ? -0.87403  55.45800 18.96992  1.000 29.46036  ? 103 TRP A CZ3 1 
ATOM   4068 C CH2 . TRP C 1 107 ? -1.90710  54.93596 18.18519  1.000 34.30884  ? 103 TRP A CH2 1 
ATOM   4069 N N   . GLY C 1 108 ? -1.08807  59.15259 24.04982  1.000 47.05572  ? 104 GLY A N   1 
ATOM   4070 C CA  . GLY C 1 108 ? 0.13501   59.38385 24.77954  1.000 50.48737  ? 104 GLY A CA  1 
ATOM   4071 C C   . GLY C 1 108 ? 1.34310   59.36141 23.86224  1.000 49.51771  ? 104 GLY A C   1 
ATOM   4072 O O   . GLY C 1 108 ? 1.28378   58.89572 22.72481  1.000 40.61318  ? 104 GLY A O   1 
ATOM   4073 N N   . GLN C 1 109 ? 2.46200   59.87487 24.37535  1.000 47.27851  ? 105 GLN A N   1 
ATOM   4074 C CA  . GLN C 1 109 ? 3.66284   60.00488 23.55502  1.000 47.05202  ? 105 GLN A CA  1 
ATOM   4075 C C   . GLN C 1 109 ? 4.33874   58.66391 23.29612  1.000 39.22217  ? 105 GLN A C   1 
ATOM   4076 O O   . GLN C 1 109 ? 5.15894   58.56283 22.37644  1.000 45.39645  ? 105 GLN A O   1 
ATOM   4077 C CB  . GLN C 1 109 ? 4.64812   60.97703 24.21794  1.000 50.91578  ? 105 GLN A CB  1 
ATOM   4078 C CG  . GLN C 1 109 ? 5.48408   60.38906 25.36282  1.000 49.56870  ? 105 GLN A CG  1 
ATOM   4079 C CD  . GLN C 1 109 ? 4.71081   60.19854 26.67029  1.000 61.20978  ? 105 GLN A CD  1 
ATOM   4080 O OE1 . GLN C 1 109 ? 3.59925   60.70757 26.84543  1.000 56.00613  ? 105 GLN A OE1 1 
ATOM   4081 N NE2 . GLN C 1 109 ? 5.30986   59.45925 27.59804  1.000 58.97594  ? 105 GLN A NE2 1 
ATOM   4082 N N   . GLY C 1 110 ? 4.00870   57.63784 24.07699  1.000 39.54776  ? 106 GLY A N   1 
ATOM   4083 C CA  . GLY C 1 110 ? 4.60579   56.32490 23.92427  1.000 41.72048  ? 106 GLY A CA  1 
ATOM   4084 C C   . GLY C 1 110 ? 5.77909   56.10019 24.85551  1.000 39.38943  ? 106 GLY A C   1 
ATOM   4085 O O   . GLY C 1 110 ? 6.61863   56.98717 25.02351  1.000 37.50486  ? 106 GLY A O   1 
ATOM   4086 N N   . THR C 1 111 ? 5.85833   54.92423 25.46789  1.000 32.27564  ? 107 THR A N   1 
ATOM   4087 C CA  . THR C 1 111 ? 6.98162   54.58726 26.33125  1.000 36.69647  ? 107 THR A CA  1 
ATOM   4088 C C   . THR C 1 111 ? 7.58475   53.26508 25.86737  1.000 38.98225  ? 107 THR A C   1 
ATOM   4089 O O   . THR C 1 111 ? 6.85453   52.30986 25.57653  1.000 36.09520  ? 107 THR A O   1 
ATOM   4090 C CB  . THR C 1 111 ? 6.54618   54.53428 27.81442  1.000 41.45473  ? 107 THR A CB  1 
ATOM   4091 O OG1 . THR C 1 111 ? 7.60976   54.01650 28.62694  1.000 45.30427  ? 107 THR A OG1 1 
ATOM   4092 C CG2 . THR C 1 111 ? 5.29325   53.68406 28.00913  1.000 46.12297  ? 107 THR A CG2 1 
ATOM   4093 N N   . LEU C 1 112 ? 8.91365   53.22131 25.77526  1.000 28.79379  ? 108 LEU A N   1 
ATOM   4094 C CA  . LEU C 1 112 ? 9.60958   52.02184 25.32884  1.000 29.27241  ? 108 LEU A CA  1 
ATOM   4095 C C   . LEU C 1 112 ? 9.75674   51.02075 26.46676  1.000 31.47566  ? 108 LEU A C   1 
ATOM   4096 O O   . LEU C 1 112 ? 10.18139  51.38071 27.56945  1.000 32.63201  ? 108 LEU A O   1 
ATOM   4097 C CB  . LEU C 1 112 ? 10.98561  52.38717 24.77656  1.000 30.37093  ? 108 LEU A CB  1 
ATOM   4098 C CG  . LEU C 1 112 ? 11.85753  51.23335 24.28053  1.000 29.59526  ? 108 LEU A CG  1 
ATOM   4099 C CD1 . LEU C 1 112 ? 11.13769  50.39757 23.23459  1.000 26.60850  ? 108 LEU A CD1 1 
ATOM   4100 C CD2 . LEU C 1 112 ? 13.14959  51.77709 23.70144  1.000 37.11683  ? 108 LEU A CD2 1 
ATOM   4101 N N   . VAL C 1 113 ? 9.41008   49.76158 26.19774  1.000 28.81126  ? 109 VAL A N   1 
ATOM   4102 C CA  . VAL C 1 113 ? 9.64783   48.65600 27.12200  1.000 25.70843  ? 109 VAL A CA  1 
ATOM   4103 C C   . VAL C 1 113 ? 10.52084  47.63598 26.41339  1.000 26.10170  ? 109 VAL A C   1 
ATOM   4104 O O   . VAL C 1 113 ? 10.15198  47.12150 25.34918  1.000 28.50223  ? 109 VAL A O   1 
ATOM   4105 C CB  . VAL C 1 113 ? 8.34355   48.00122 27.60683  1.000 30.89989  ? 109 VAL A CB  1 
ATOM   4106 C CG1 . VAL C 1 113 ? 8.65575   46.81601 28.52966  1.000 24.89328  ? 109 VAL A CG1 1 
ATOM   4107 C CG2 . VAL C 1 113 ? 7.46640   49.01617 28.30894  1.000 30.65939  ? 109 VAL A CG2 1 
ATOM   4108 N N   . THR C 1 114 ? 11.67840  47.35133 26.98643  1.000 20.24765  ? 110 THR A N   1 
ATOM   4109 C CA  . THR C 1 114 ? 12.58860  46.36287 26.42806  1.000 25.75938  ? 110 THR A CA  1 
ATOM   4110 C C   . THR C 1 114 ? 12.56325  45.13733 27.32727  1.000 30.63869  ? 110 THR A C   1 
ATOM   4111 O O   . THR C 1 114 ? 12.63772  45.25793 28.55484  1.000 31.64422  ? 110 THR A O   1 
ATOM   4112 C CB  . THR C 1 114 ? 14.00701  46.92957 26.29176  1.000 22.81413  ? 110 THR A CB  1 
ATOM   4113 O OG1 . THR C 1 114 ? 13.96867  48.08966 25.45480  1.000 24.02192  ? 110 THR A OG1 1 
ATOM   4114 C CG2 . THR C 1 114 ? 14.96471  45.90870 25.68414  1.000 23.05431  ? 110 THR A CG2 1 
ATOM   4115 N N   . VAL C 1 115 ? 12.41139  43.97144 26.71920  1.000 28.30509  ? 111 VAL A N   1 
ATOM   4116 C CA  . VAL C 1 115 ? 12.39322  42.69770 27.42974  1.000 30.05896  ? 111 VAL A CA  1 
ATOM   4117 C C   . VAL C 1 115 ? 13.66425  41.97131 27.03542  1.000 29.40913  ? 111 VAL A C   1 
ATOM   4118 O O   . VAL C 1 115 ? 13.78686  41.48507 25.90431  1.000 29.25224  ? 111 VAL A O   1 
ATOM   4119 C CB  . VAL C 1 115 ? 11.15172  41.86247 27.09146  1.000 32.50512  ? 111 VAL A CB  1 
ATOM   4120 C CG1 . VAL C 1 115 ? 11.21139  40.51801 27.80460  1.000 30.12779  ? 111 VAL A CG1 1 
ATOM   4121 C CG2 . VAL C 1 115 ? 9.88132   42.62880 27.44407  1.000 31.38338  ? 111 VAL A CG2 1 
ATOM   4122 N N   . SER C 1 116 ? 14.61695  41.90830 27.95602  1.000 23.79746  ? 112 SER A N   1 
ATOM   4123 C CA  . SER C 1 116 ? 15.91233  41.32607 27.64764  1.000 25.89305  ? 112 SER A CA  1 
ATOM   4124 C C   . SER C 1 116 ? 16.63373  41.06786 28.95464  1.000 25.10251  ? 112 SER A C   1 
ATOM   4125 O O   . SER C 1 116 ? 16.38121  41.75191 29.94906  1.000 27.39969  ? 112 SER A O   1 
ATOM   4126 C CB  . SER C 1 116 ? 16.73957  42.26225 26.75329  1.000 22.52205  ? 112 SER A CB  1 
ATOM   4127 O OG  . SER C 1 116 ? 18.04526  41.74832 26.54627  1.000 23.11363  ? 112 SER A OG  1 
ATOM   4128 N N   . SER C 1 117 ? 17.52943  40.08361 28.95331  1.000 25.54374  ? 113 SER A N   1 
ATOM   4129 C CA  . SER C 1 117 ? 18.40340  39.88158 30.10315  1.000 28.30660  ? 113 SER A CA  1 
ATOM   4130 C C   . SER C 1 117 ? 19.79508  40.47130 29.90146  1.000 29.37516  ? 113 SER A C   1 
ATOM   4131 O O   . SER C 1 117 ? 20.66321  40.26372 30.75424  1.000 24.97267  ? 113 SER A O   1 
ATOM   4132 C CB  . SER C 1 117 ? 18.52608  38.39158 30.44266  1.000 25.99622  ? 113 SER A CB  1 
ATOM   4133 O OG  . SER C 1 117 ? 19.18588  37.68082 29.40942  1.000 23.82928  ? 113 SER A OG  1 
ATOM   4134 N N   . ALA C 1 118 ? 20.03702  41.17126 28.79110  1.000 26.03985  ? 114 ALA A N   1 
ATOM   4135 C CA  . ALA C 1 118 ? 21.29110  41.89081 28.62858  1.000 29.59312  ? 114 ALA A CA  1 
ATOM   4136 C C   . ALA C 1 118 ? 21.35287  43.03783 29.63390  1.000 28.39366  ? 114 ALA A C   1 
ATOM   4137 O O   . ALA C 1 118 ? 20.32556  43.56966 30.05785  1.000 23.40561  ? 114 ALA A O   1 
ATOM   4138 C CB  . ALA C 1 118 ? 21.42766  42.41927 27.19584  1.000 24.30459  ? 114 ALA A CB  1 
ATOM   4139 N N   . SER C 1 119 ? 22.56758  43.41187 30.02913  1.000 29.48408  ? 115 SER A N   1 
ATOM   4140 C CA  . SER C 1 119 ? 22.74630  44.44471 31.04991  1.000 30.20806  ? 115 SER A CA  1 
ATOM   4141 C C   . SER C 1 119 ? 22.87858  45.84152 30.44044  1.000 26.79802  ? 115 SER A C   1 
ATOM   4142 O O   . SER C 1 119 ? 23.53087  46.02679 29.40613  1.000 25.64512  ? 115 SER A O   1 
ATOM   4143 C CB  . SER C 1 119 ? 23.97989  44.14155 31.90337  1.000 35.88920  ? 115 SER A CB  1 
ATOM   4144 O OG  . SER C 1 119 ? 23.80562  42.94884 32.66232  1.000 36.65595  ? 115 SER A OG  1 
ATOM   4145 N N   . THR C 1 120 ? 22.27157  46.82317 31.11203  1.000 25.79103  ? 116 THR A N   1 
ATOM   4146 C CA  . THR C 1 120 ? 22.37353  48.21932 30.70420  1.000 22.82002  ? 116 THR A CA  1 
ATOM   4147 C C   . THR C 1 120 ? 23.83408  48.64686 30.59794  1.000 24.77260  ? 116 THR A C   1 
ATOM   4148 O O   . THR C 1 120 ? 24.63995  48.39253 31.49599  1.000 20.93124  ? 116 THR A O   1 
ATOM   4149 C CB  . THR C 1 120 ? 21.62065  49.09936 31.69441  1.000 24.66541  ? 116 THR A CB  1 
ATOM   4150 O OG1 . THR C 1 120 ? 20.22414  48.79707 31.60626  1.000 25.55747  ? 116 THR A OG1 1 
ATOM   4151 C CG2 . THR C 1 120 ? 21.84674  50.59202 31.39967  1.000 20.19874  ? 116 THR A CG2 1 
ATOM   4152 N N   . LYS C 1 121 ? 24.18632  49.26498 29.47165  1.000 19.07916  ? 117 LYS A N   1 
ATOM   4153 C CA  . LYS C 1 121 ? 25.58253  49.56200 29.17736  1.000 18.83294  ? 117 LYS A CA  1 
ATOM   4154 C C   . LYS C 1 121 ? 25.63633  50.74910 28.22225  1.000 26.23242  ? 117 LYS A C   1 
ATOM   4155 O O   . LYS C 1 121 ? 24.94267  50.74413 27.19971  1.000 22.15563  ? 117 LYS A O   1 
ATOM   4156 C CB  . LYS C 1 121 ? 26.26252  48.33602 28.55378  1.000 23.09484  ? 117 LYS A CB  1 
ATOM   4157 C CG  . LYS C 1 121 ? 27.71668  48.51216 28.17551  1.000 29.63675  ? 117 LYS A CG  1 
ATOM   4158 C CD  . LYS C 1 121 ? 28.21252  47.30210 27.41224  1.000 32.52557  ? 117 LYS A CD  1 
ATOM   4159 C CE  . LYS C 1 121 ? 29.54942  47.57432 26.71580  1.000 42.78490  ? 117 LYS A CE  1 
ATOM   4160 N NZ  . LYS C 1 121 ? 29.50794  48.73623 25.74816  1.000 35.15261  ? 117 LYS A NZ  1 
ATOM   4161 N N   . GLY C 1 122 ? 26.45087  51.75465 28.54772  1.000 20.31005  ? 118 GLY A N   1 
ATOM   4162 C CA  . GLY C 1 122 ? 26.65915  52.87743 27.65218  1.000 20.40627  ? 118 GLY A CA  1 
ATOM   4163 C C   . GLY C 1 122 ? 27.51345  52.46973 26.46684  1.000 19.34931  ? 118 GLY A C   1 
ATOM   4164 O O   . GLY C 1 122 ? 28.18695  51.43515 26.48996  1.000 17.92430  ? 118 GLY A O   1 
ATOM   4165 N N   . PRO C 1 123 ? 27.50299  53.26886 25.40062  1.000 25.90525  ? 119 PRO A N   1 
ATOM   4166 C CA  . PRO C 1 123 ? 28.21158  52.86965 24.18280  1.000 22.13650  ? 119 PRO A CA  1 
ATOM   4167 C C   . PRO C 1 123 ? 29.70344  53.13459 24.25555  1.000 18.82192  ? 119 PRO A C   1 
ATOM   4168 O O   . PRO C 1 123 ? 30.17085  54.02111 24.97216  1.000 19.29460  ? 119 PRO A O   1 
ATOM   4169 C CB  . PRO C 1 123 ? 27.57329  53.74860 23.10496  1.000 18.85052  ? 119 PRO A CB  1 
ATOM   4170 C CG  . PRO C 1 123 ? 27.27210  55.02785 23.84790  1.000 20.63604  ? 119 PRO A CG  1 
ATOM   4171 C CD  . PRO C 1 123 ? 26.87883  54.59970 25.26279  1.000 21.25043  ? 119 PRO A CD  1 
ATOM   4172 N N   . SER C 1 124 ? 30.44404  52.33489 23.49104  1.000 18.29624  ? 120 SER A N   1 
ATOM   4173 C CA  . SER C 1 124 ? 31.78225  52.69135 23.04102  1.000 21.03729  ? 120 SER A CA  1 
ATOM   4174 C C   . SER C 1 124 ? 31.63858  53.47264 21.73883  1.000 24.96901  ? 120 SER A C   1 
ATOM   4175 O O   . SER C 1 124 ? 30.91587  53.03829 20.83704  1.000 28.59923  ? 120 SER A O   1 
ATOM   4176 C CB  . SER C 1 124 ? 32.62501  51.43418 22.81790  1.000 29.77217  ? 120 SER A CB  1 
ATOM   4177 O OG  . SER C 1 124 ? 32.54454  50.55390 23.92406  1.000 31.96596  ? 120 SER A OG  1 
ATOM   4178 N N   . VAL C 1 125 ? 32.31009  54.62114 21.63853  1.000 23.08425  ? 121 VAL A N   1 
ATOM   4179 C CA  . VAL C 1 125 ? 32.19602  55.49058 20.47008  1.000 22.38238  ? 121 VAL A CA  1 
ATOM   4180 C C   . VAL C 1 125 ? 33.54808  55.54567 19.77254  1.000 23.86593  ? 121 VAL A C   1 
ATOM   4181 O O   . VAL C 1 125 ? 34.53590  56.01201 20.34749  1.000 25.38423  ? 121 VAL A O   1 
ATOM   4182 C CB  . VAL C 1 125 ? 31.71539  56.89745 20.84816  1.000 24.79201  ? 121 VAL A CB  1 
ATOM   4183 C CG1 . VAL C 1 125 ? 31.60351  57.76609 19.59512  1.000 19.37687  ? 121 VAL A CG1 1 
ATOM   4184 C CG2 . VAL C 1 125 ? 30.37643  56.82498 21.58407  1.000 18.98290  ? 121 VAL A CG2 1 
ATOM   4185 N N   . PHE C 1 126 ? 33.59173  55.06961 18.54012  1.000 16.97462  ? 122 PHE A N   1 
ATOM   4186 C CA  . PHE C 1 126 ? 34.80757  55.01122 17.76054  1.000 23.09100  ? 122 PHE A CA  1 
ATOM   4187 C C   . PHE C 1 126 ? 34.71638  55.96091 16.57365  1.000 21.65239  ? 122 PHE A C   1 
ATOM   4188 O O   . PHE C 1 126 ? 33.63238  56.16087 16.02463  1.000 19.79220  ? 122 PHE A O   1 
ATOM   4189 C CB  . PHE C 1 126 ? 35.04979  53.58485 17.25689  1.000 17.94409  ? 122 PHE A CB  1 
ATOM   4190 C CG  . PHE C 1 126 ? 35.15009  52.56919 18.37004  1.000 22.62198  ? 122 PHE A CG  1 
ATOM   4191 C CD1 . PHE C 1 126 ? 36.20553  52.61378 19.26521  1.000 22.37203  ? 122 PHE A CD1 1 
ATOM   4192 C CD2 . PHE C 1 126 ? 34.20865  51.55454 18.49357  1.000 20.89971  ? 122 PHE A CD2 1 
ATOM   4193 C CE1 . PHE C 1 126 ? 36.30725  51.68536 20.28911  1.000 28.30659  ? 122 PHE A CE1 1 
ATOM   4194 C CE2 . PHE C 1 126 ? 34.31471  50.61462 19.51380  1.000 25.01602  ? 122 PHE A CE2 1 
ATOM   4195 C CZ  . PHE C 1 126 ? 35.36212  50.68421 20.40603  1.000 22.06742  ? 122 PHE A CZ  1 
ATOM   4196 N N   . PRO C 1 127 ? 35.82692  56.56452 16.15706  1.000 22.15101  ? 123 PRO A N   1 
ATOM   4197 C CA  . PRO C 1 127 ? 35.78141  57.48472 15.00942  1.000 19.46284  ? 123 PRO A CA  1 
ATOM   4198 C C   . PRO C 1 127 ? 35.68170  56.73115 13.68918  1.000 22.70879  ? 123 PRO A C   1 
ATOM   4199 O O   . PRO C 1 127 ? 36.29763  55.68114 13.50397  1.000 23.17790  ? 123 PRO A O   1 
ATOM   4200 C CB  . PRO C 1 127 ? 37.11713  58.23606 15.11555  1.000 23.11621  ? 123 PRO A CB  1 
ATOM   4201 C CG  . PRO C 1 127 ? 38.04465  57.22100 15.75460  1.000 26.25485  ? 123 PRO A CG  1 
ATOM   4202 C CD  . PRO C 1 127 ? 37.17103  56.48587 16.76040  1.000 18.55262  ? 123 PRO A CD  1 
ATOM   4203 N N   . LEU C 1 128 ? 34.87451  57.25993 12.77366  1.000 22.06051  ? 124 LEU A N   1 
ATOM   4204 C CA  . LEU C 1 128 ? 34.91812  56.85668 11.36393  1.000 23.58170  ? 124 LEU A CA  1 
ATOM   4205 C C   . LEU C 1 128 ? 35.69854  57.95282 10.64210  1.000 27.02223  ? 124 LEU A C   1 
ATOM   4206 O O   . LEU C 1 128 ? 35.15236  59.01046 10.31133  1.000 19.16569  ? 124 LEU A O   1 
ATOM   4207 C CB  . LEU C 1 128 ? 33.52152  56.67567 10.79133  1.000 22.28654  ? 124 LEU A CB  1 
ATOM   4208 C CG  . LEU C 1 128 ? 32.72738  55.53111 11.43456  1.000 21.74173  ? 124 LEU A CG  1 
ATOM   4209 C CD1 . LEU C 1 128 ? 31.25918  55.65567 11.10898  1.000 16.51652  ? 124 LEU A CD1 1 
ATOM   4210 C CD2 . LEU C 1 128 ? 33.27149  54.16641 11.00361  1.000 20.48346  ? 124 LEU A CD2 1 
ATOM   4211 N N   . ALA C 1 129 ? 36.97878  57.70019 10.42124  1.000 28.30663  ? 125 ALA A N   1 
ATOM   4212 C CA  . ALA C 1 129 ? 37.82945  58.85193 10.16239  1.000 41.25257  ? 125 ALA A CA  1 
ATOM   4213 C C   . ALA C 1 129 ? 37.98784  59.07526 8.66604   1.000 38.95224  ? 125 ALA A C   1 
ATOM   4214 O O   . ALA C 1 129 ? 38.10090  58.10935 7.90337   1.000 39.77958  ? 125 ALA A O   1 
ATOM   4215 C CB  . ALA C 1 129 ? 39.20915  58.66302 10.78987  1.000 36.73191  ? 125 ALA A CB  1 
ATOM   4216 N N   . PRO C 1 130 ? 38.00004  60.34101 8.24316   1.000 42.30264  ? 126 PRO A N   1 
ATOM   4217 C CA  . PRO C 1 130 ? 38.37230  60.65005 6.85739   1.000 48.59795  ? 126 PRO A CA  1 
ATOM   4218 C C   . PRO C 1 130 ? 39.88660  60.54405 6.72017   1.000 58.01568  ? 126 PRO A C   1 
ATOM   4219 O O   . PRO C 1 130 ? 40.63374  61.08778 7.53886   1.000 51.82925  ? 126 PRO A O   1 
ATOM   4220 C CB  . PRO C 1 130 ? 37.87310  62.08711 6.66817   1.000 33.08776  ? 126 PRO A CB  1 
ATOM   4221 C CG  . PRO C 1 130 ? 37.99197  62.69739 8.05468   1.000 38.81724  ? 126 PRO A CG  1 
ATOM   4222 C CD  . PRO C 1 130 ? 37.84297  61.55805 9.06227   1.000 37.06304  ? 126 PRO A CD  1 
ATOM   4223 N N   . SER C 1 131 ? 40.33552  59.81609 5.69618   1.000 73.17324  ? 127 SER A N   1 
ATOM   4224 C CA  . SER C 1 131 ? 41.74131  59.44103 5.56910   1.000 78.44523  ? 127 SER A CA  1 
ATOM   4225 C C   . SER C 1 131 ? 42.63001  60.66713 5.31824   1.000 84.94456  ? 127 SER A C   1 
ATOM   4226 O O   . SER C 1 131 ? 42.15489  61.78781 5.09710   1.000 77.47075  ? 127 SER A O   1 
ATOM   4227 C CB  . SER C 1 131 ? 41.91344  58.41565 4.44400   1.000 86.30758  ? 127 SER A CB  1 
ATOM   4228 O OG  . SER C 1 131 ? 43.19654  57.80657 4.47041   1.000 77.09681  ? 127 SER A OG  1 
ATOM   4229 N N   . SER C 1 132 ? 43.95030  60.43339 5.36811   1.000 86.06573  ? 128 SER A N   1 
ATOM   4230 C CA  . SER C 1 132 ? 44.91601  61.48402 5.04754   1.000 83.61776  ? 128 SER A CA  1 
ATOM   4231 C C   . SER C 1 132 ? 44.73650  61.98011 3.61864   1.000 90.54408  ? 128 SER A C   1 
ATOM   4232 O O   . SER C 1 132 ? 44.87803  63.17838 3.34444   1.000 90.02504  ? 128 SER A O   1 
ATOM   4233 C CB  . SER C 1 132 ? 46.34199  60.96838 5.24920   1.000 86.39965  ? 128 SER A CB  1 
ATOM   4234 O OG  . SER C 1 132 ? 47.30764  61.96009 4.93127   1.000 85.96679  ? 128 SER A OG  1 
ATOM   4235 N N   . LYS C 1 133 ? 44.43379  61.06871 2.69381   1.000 85.82806  ? 129 LYS A N   1 
ATOM   4236 C CA  . LYS C 1 133 ? 44.16369  61.41540 1.30513   1.000 83.83579  ? 129 LYS A CA  1 
ATOM   4237 C C   . LYS C 1 133 ? 42.67531  61.64062 1.05137   1.000 86.62183  ? 129 LYS A C   1 
ATOM   4238 O O   . LYS C 1 133 ? 42.30413  62.56745 0.31839   1.000 82.07100  ? 129 LYS A O   1 
ATOM   4239 C CB  . LYS C 1 133 ? 44.68947  60.31024 0.38182   1.000 82.28030  ? 129 LYS A CB  1 
ATOM   4240 C CG  . LYS C 1 133 ? 44.64094  60.65398 -1.10020  1.000 80.60793  ? 129 LYS A CG  1 
ATOM   4241 C CD  . LYS C 1 133 ? 45.65336  61.74333 -1.44919  1.000 70.82064  ? 129 LYS A CD  1 
ATOM   4242 C CE  . LYS C 1 133 ? 45.24112  62.47696 -2.70888  1.000 37.98550  ? 129 LYS A CE  1 
ATOM   4243 N NZ  . LYS C 1 133 ? 43.81450  62.89027 -2.58317  1.000 46.27705  ? 129 LYS A NZ  1 
ATOM   4244 N N   . SER C 1 134 ? 41.82143  60.79199 1.63906   1.000 90.06974  ? 130 SER A N   1 
ATOM   4245 C CA  . SER C 1 134 ? 40.36731  60.82631 1.48409   1.000 84.09400  ? 130 SER A CA  1 
ATOM   4246 C C   . SER C 1 134 ? 39.94531  60.58403 0.04052   1.000 79.31599  ? 130 SER A C   1 
ATOM   4247 O O   . SER C 1 134 ? 38.74589  60.49606 -0.24592  1.000 77.84342  ? 130 SER A O   1 
ATOM   4248 C CB  . SER C 1 134 ? 39.78788  62.15552 1.98658   1.000 81.39552  ? 130 SER A CB  1 
ATOM   4249 O OG  . SER C 1 134 ? 39.81815  62.23451 3.40187   1.000 71.10288  ? 130 SER A OG  1 
ATOM   4250 N N   . THR C 1 135 ? 40.92522  60.44767 -0.85899  1.000 76.29995  ? 131 THR A N   1 
ATOM   4251 C CA  . THR C 1 135 ? 40.70793  60.31872 -2.29704  1.000 73.46296  ? 131 THR A CA  1 
ATOM   4252 C C   . THR C 1 135 ? 39.57727  61.23162 -2.76792  1.000 69.84337  ? 131 THR A C   1 
ATOM   4253 O O   . THR C 1 135 ? 39.79100  62.44023 -2.91731  1.000 70.90736  ? 131 THR A O   1 
ATOM   4254 C CB  . THR C 1 135 ? 40.44653  58.85247 -2.67609  1.000 66.94754  ? 131 THR A CB  1 
ATOM   4255 O OG1 . THR C 1 135 ? 39.37347  58.31379 -1.88928  1.000 76.58290  ? 131 THR A OG1 1 
ATOM   4256 C CG2 . THR C 1 135 ? 41.71241  58.01765 -2.44988  1.000 56.07493  ? 131 THR A CG2 1 
ATOM   4257 N N   . SER C 1 136 ? 38.38415  60.65484 -2.98050  1.000 67.34061  ? 132 SER A N   1 
ATOM   4258 C CA  . SER C 1 136 ? 37.12644  61.30982 -3.36502  1.000 57.75121  ? 132 SER A CA  1 
ATOM   4259 C C   . SER C 1 136 ? 37.17853  62.81589 -3.62077  1.000 60.15217  ? 132 SER A C   1 
ATOM   4260 O O   . SER C 1 136 ? 37.21564  63.61653 -2.67570  1.000 57.82100  ? 132 SER A O   1 
ATOM   4261 C CB  . SER C 1 136 ? 36.06244  61.04988 -2.29696  1.000 62.96405  ? 132 SER A CB  1 
ATOM   4262 O OG  . SER C 1 136 ? 34.87309  61.76856 -2.59585  1.000 59.59541  ? 132 SER A OG  1 
ATOM   4263 N N   . GLY C 1 137 ? 37.12910  63.20286 -4.89754  1.000 57.94399  ? 133 GLY A N   1 
ATOM   4264 C CA  . GLY C 1 137 ? 37.12630  64.59546 -5.30973  1.000 49.40153  ? 133 GLY A CA  1 
ATOM   4265 C C   . GLY C 1 137 ? 36.12993  65.51058 -4.61878  1.000 49.87391  ? 133 GLY A C   1 
ATOM   4266 O O   . GLY C 1 137 ? 34.97494  65.63159 -5.04130  1.000 61.39207  ? 133 GLY A O   1 
ATOM   4267 N N   . GLY C 1 138 ? 36.57092  66.15290 -3.54182  1.000 37.63199  ? 134 GLY A N   1 
ATOM   4268 C CA  . GLY C 1 138 ? 35.85115  67.28419 -2.99740  1.000 37.03209  ? 134 GLY A CA  1 
ATOM   4269 C C   . GLY C 1 138 ? 35.12929  67.06292 -1.68524  1.000 35.54475  ? 134 GLY A C   1 
ATOM   4270 O O   . GLY C 1 138 ? 35.25459  67.86952 -0.75896  1.000 35.06078  ? 134 GLY A O   1 
ATOM   4271 N N   . THR C 1 139 ? 34.36688  65.97991 -1.60369  1.000 29.34672  ? 135 THR A N   1 
ATOM   4272 C CA  . THR C 1 139 ? 33.46384  65.71741 -0.49420  1.000 34.74830  ? 135 THR A CA  1 
ATOM   4273 C C   . THR C 1 139 ? 33.99061  64.52890 0.30104   1.000 33.63318  ? 135 THR A C   1 
ATOM   4274 O O   . THR C 1 139 ? 34.17590  63.44210 -0.25663  1.000 28.57420  ? 135 THR A O   1 
ATOM   4275 C CB  . THR C 1 139 ? 32.05046  65.45401 -1.01257  1.000 32.73753  ? 135 THR A CB  1 
ATOM   4276 O OG1 . THR C 1 139 ? 31.55033  66.64569 -1.63237  1.000 39.33990  ? 135 THR A OG1 1 
ATOM   4277 C CG2 . THR C 1 139 ? 31.11930  65.04594 0.11661   1.000 33.55974  ? 135 THR A CG2 1 
ATOM   4278 N N   . ALA C 1 140 ? 34.25137  64.75069 1.59276   1.000 32.02000  ? 136 ALA A N   1 
ATOM   4279 C CA  . ALA C 1 140 ? 34.73750  63.73438 2.51642   1.000 27.60095  ? 136 ALA A CA  1 
ATOM   4280 C C   . ALA C 1 140 ? 33.59989  63.26672 3.41359   1.000 28.79844  ? 136 ALA A C   1 
ATOM   4281 O O   . ALA C 1 140 ? 32.63797  63.99767 3.65814   1.000 27.63268  ? 136 ALA A O   1 
ATOM   4282 C CB  . ALA C 1 140 ? 35.87992  64.27860 3.37932   1.000 20.06701  ? 136 ALA A CB  1 
ATOM   4283 N N   . ALA C 1 141 ? 33.70443  62.03461 3.89400   1.000 21.29132  ? 137 ALA A N   1 
ATOM   4284 C CA  . ALA C 1 141 ? 32.74058  61.50945 4.84888   1.000 25.40631  ? 137 ALA A CA  1 
ATOM   4285 C C   . ALA C 1 141 ? 33.46709  61.19555 6.14935   1.000 16.88273  ? 137 ALA A C   1 
ATOM   4286 O O   . ALA C 1 141 ? 34.59943  60.70870 6.14118   1.000 19.85571  ? 137 ALA A O   1 
ATOM   4287 C CB  . ALA C 1 141 ? 32.02002  60.26445 4.31574   1.000 21.31718  ? 137 ALA A CB  1 
ATOM   4288 N N   . LEU C 1 142 ? 32.83843  61.52140 7.26483   1.000 18.39312  ? 138 LEU A N   1 
ATOM   4289 C CA  . LEU C 1 142 ? 33.39662  61.18076 8.56256   1.000 17.02133  ? 138 LEU A CA  1 
ATOM   4290 C C   . LEU C 1 142 ? 32.23342  60.78343 9.45226   1.000 20.76858  ? 138 LEU A C   1 
ATOM   4291 O O   . LEU C 1 142 ? 31.07408  61.00968 9.10702   1.000 17.71720  ? 138 LEU A O   1 
ATOM   4292 C CB  . LEU C 1 142 ? 34.20269  62.34501 9.14516   1.000 19.25369  ? 138 LEU A CB  1 
ATOM   4293 C CG  . LEU C 1 142 ? 33.40066  63.62095 9.40276   1.000 29.08230  ? 138 LEU A CG  1 
ATOM   4294 C CD1 . LEU C 1 142 ? 33.04295  63.75006 10.88279  1.000 25.83210  ? 138 LEU A CD1 1 
ATOM   4295 C CD2 . LEU C 1 142 ? 34.17254  64.84436 8.91750   1.000 36.18881  ? 138 LEU A CD2 1 
ATOM   4296 N N   . GLY C 1 143 ? 32.52728  60.17021 10.59516  1.000 23.52041  ? 139 GLY A N   1 
ATOM   4297 C CA  . GLY C 1 143 ? 31.43016  59.81406 11.47211  1.000 21.20114  ? 139 GLY A CA  1 
ATOM   4298 C C   . GLY C 1 143 ? 31.88984  59.18742 12.77214  1.000 20.94636  ? 139 GLY A C   1 
ATOM   4299 O O   . GLY C 1 143 ? 33.07505  59.16703 13.10545  1.000 13.63049  ? 139 GLY A O   1 
ATOM   4300 N N   . CYS C 1 144 ? 30.91643  58.68045 13.51802  1.000 15.88825  ? 140 CYS A N   1 
ATOM   4301 C CA  A CYS C 1 144 ? 31.16053  57.94976 14.75449  0.714 21.51679  ? 140 CYS A CA  1 
ATOM   4302 C CA  B CYS C 1 144 ? 31.27735  57.87941 14.66723  0.286 21.35569  ? 140 CYS A CA  1 
ATOM   4303 C C   . CYS C 1 144 ? 30.40402  56.63524 14.73233  1.000 19.39973  ? 140 CYS A C   1 
ATOM   4304 O O   . CYS C 1 144 ? 29.21869  56.62900 14.38343  1.000 21.25135  ? 140 CYS A O   1 
ATOM   4305 C CB  A CYS C 1 144 ? 30.68577  58.73847 15.95298  0.714 18.00546  ? 140 CYS A CB  1 
ATOM   4306 C CB  B CYS C 1 144 ? 31.26977  58.69282 15.98943  0.286 19.06762  ? 140 CYS A CB  1 
ATOM   4307 S SG  A CYS C 1 144 ? 31.69435  60.12262 16.40075  0.714 22.56982  ? 140 CYS A SG  1 
ATOM   4308 S SG  B CYS C 1 144 ? 29.77946  59.48767 16.66105  0.286 19.09708  ? 140 CYS A SG  1 
ATOM   4309 N N   . LEU C 1 145 ? 31.06616  55.56271 15.11716  1.000 17.58937  ? 141 LEU A N   1 
ATOM   4310 C CA  . LEU C 1 145 ? 30.46829  54.25342 15.28265  1.000 19.45233  ? 141 LEU A CA  1 
ATOM   4311 C C   . LEU C 1 145 ? 30.08877  54.10915 16.75661  1.000 19.82951  ? 141 LEU A C   1 
ATOM   4312 O O   . LEU C 1 145 ? 30.95598  54.19787 17.63274  1.000 18.61001  ? 141 LEU A O   1 
ATOM   4313 C CB  . LEU C 1 145 ? 31.47522  53.18765 14.86235  1.000 18.81617  ? 141 LEU A CB  1 
ATOM   4314 C CG  . LEU C 1 145 ? 31.10145  51.74171 15.15278  1.000 19.60743  ? 141 LEU A CG  1 
ATOM   4315 C CD1 . LEU C 1 145 ? 29.79553  51.40592 14.46367  1.000 21.67333  ? 141 LEU A CD1 1 
ATOM   4316 C CD2 . LEU C 1 145 ? 32.22539  50.80753 14.73485  1.000 22.97424  ? 141 LEU A CD2 1 
ATOM   4317 N N   . VAL C 1 146 ? 28.80028  53.94803 17.03272  1.000 18.59682  ? 142 VAL A N   1 
ATOM   4318 C CA  . VAL C 1 146 ? 28.29100  53.94791 18.40514  1.000 21.13885  ? 142 VAL A CA  1 
ATOM   4319 C C   . VAL C 1 146 ? 27.93734  52.50293 18.73153  1.000 24.55624  ? 142 VAL A C   1 
ATOM   4320 O O   . VAL C 1 146 ? 26.84653  52.03054 18.38542  1.000 24.36184  ? 142 VAL A O   1 
ATOM   4321 C CB  . VAL C 1 146 ? 27.08554  54.87957 18.56783  1.000 21.38792  ? 142 VAL A CB  1 
ATOM   4322 C CG1 . VAL C 1 146 ? 26.51862  54.78027 19.97945  1.000 20.47670  ? 142 VAL A CG1 1 
ATOM   4323 C CG2 . VAL C 1 146 ? 27.47927  56.32829 18.24164  1.000 17.82625  ? 142 VAL A CG2 1 
ATOM   4324 N N   . LYS C 1 147 ? 28.85415  51.79878 19.39437  1.000 20.17898  ? 143 LYS A N   1 
ATOM   4325 C CA  . LYS C 1 147 ? 28.83245  50.34078 19.46424  1.000 20.19690  ? 143 LYS A CA  1 
ATOM   4326 C C   . LYS C 1 147 ? 28.48740  49.82369 20.86300  1.000 21.91892  ? 143 LYS A C   1 
ATOM   4327 O O   . LYS C 1 147 ? 28.93930  50.37317 21.87257  1.000 20.17941  ? 143 LYS A O   1 
ATOM   4328 C CB  . LYS C 1 147 ? 30.19404  49.78086 19.03202  1.000 22.70912  ? 143 LYS A CB  1 
ATOM   4329 C CG  . LYS C 1 147 ? 30.22985  48.26995 18.85120  1.000 31.63352  ? 143 LYS A CG  1 
ATOM   4330 C CD  . LYS C 1 147 ? 31.02697  47.87812 17.62768  1.000 31.93002  ? 143 LYS A CD  1 
ATOM   4331 C CE  . LYS C 1 147 ? 31.48603  46.42976 17.70724  1.000 37.67918  ? 143 LYS A CE  1 
ATOM   4332 N NZ  . LYS C 1 147 ? 30.35422  45.49623 17.58157  1.000 35.29307  ? 143 LYS A NZ  1 
ATOM   4333 N N   . ASP C 1 148 ? 27.69458  48.74776 20.90273  1.000 21.61104  ? 144 ASP A N   1 
ATOM   4334 C CA  . ASP C 1 148 ? 27.51937  47.90599 22.09370  1.000 22.14530  ? 144 ASP A CA  1 
ATOM   4335 C C   . ASP C 1 148 ? 26.91210  48.66900 23.26879  1.000 25.60359  ? 144 ASP A C   1 
ATOM   4336 O O   . ASP C 1 148 ? 27.42456  48.64743 24.38915  1.000 28.43344  ? 144 ASP A O   1 
ATOM   4337 C CB  . ASP C 1 148 ? 28.83897  47.25653 22.50393  1.000 25.49805  ? 144 ASP A CB  1 
ATOM   4338 C CG  . ASP C 1 148 ? 29.30895  46.22866 21.50606  1.000 33.68589  ? 144 ASP A CG  1 
ATOM   4339 O OD1 . ASP C 1 148 ? 28.46973  45.72418 20.72752  1.000 31.97534  ? 144 ASP A OD1 1 
ATOM   4340 O OD2 . ASP C 1 148 ? 30.51679  45.92392 21.50696  1.000 27.58515  ? 144 ASP A OD2 1 
ATOM   4341 N N   . TYR C 1 149 ? 25.79298  49.32390 23.02238  1.000 18.00786  ? 145 TYR A N   1 
ATOM   4342 C CA  . TYR C 1 149 ? 25.04104  49.92008 24.10981  1.000 23.16312  ? 145 TYR A CA  1 
ATOM   4343 C C   . TYR C 1 149 ? 23.72165  49.18198 24.29497  1.000 25.54575  ? 145 TYR A C   1 
ATOM   4344 O O   . TYR C 1 149 ? 23.29219  48.40272 23.44007  1.000 22.29931  ? 145 TYR A O   1 
ATOM   4345 C CB  . TYR C 1 149 ? 24.78336  51.40101 23.84634  1.000 19.92094  ? 145 TYR A CB  1 
ATOM   4346 C CG  . TYR C 1 149 ? 23.85801  51.66157 22.68038  1.000 22.58084  ? 145 TYR A CG  1 
ATOM   4347 C CD1 . TYR C 1 149 ? 24.36045  51.79402 21.38396  1.000 21.50614  ? 145 TYR A CD1 1 
ATOM   4348 C CD2 . TYR C 1 149 ? 22.48940  51.80253 22.87188  1.000 20.49435  ? 145 TYR A CD2 1 
ATOM   4349 C CE1 . TYR C 1 149 ? 23.51620  52.04600 20.31485  1.000 19.65917  ? 145 TYR A CE1 1 
ATOM   4350 C CE2 . TYR C 1 149 ? 21.63891  52.05499 21.81127  1.000 21.13852  ? 145 TYR A CE2 1 
ATOM   4351 C CZ  . TYR C 1 149 ? 22.17009  52.18020 20.53532  1.000 21.29813  ? 145 TYR A CZ  1 
ATOM   4352 O OH  . TYR C 1 149 ? 21.34428  52.43995 19.48357  1.000 20.86323  ? 145 TYR A OH  1 
ATOM   4353 N N   . PHE C 1 150 ? 23.05411  49.47946 25.41459  1.000 22.36404  ? 146 PHE A N   1 
ATOM   4354 C CA  . PHE C 1 150 ? 21.81291  48.80152 25.75062  1.000 25.37241  ? 146 PHE A CA  1 
ATOM   4355 C C   . PHE C 1 150 ? 21.11212  49.47223 26.92744  1.000 23.60795  ? 146 PHE A C   1 
ATOM   4356 O O   . PHE C 1 150 ? 21.76826  49.81605 27.91434  1.000 22.58558  ? 146 PHE A O   1 
ATOM   4357 C CB  . PHE C 1 150 ? 22.08054  47.32676 26.08494  1.000 26.87495  ? 146 PHE A CB  1 
ATOM   4358 C CG  . PHE C 1 150 ? 20.82492  46.53942 26.30197  1.000 29.16772  ? 146 PHE A CG  1 
ATOM   4359 C CD1 . PHE C 1 150 ? 20.13736  46.00713 25.22017  1.000 23.75362  ? 146 PHE A CD1 1 
ATOM   4360 C CD2 . PHE C 1 150 ? 20.30342  46.37440 27.57735  1.000 33.28781  ? 146 PHE A CD2 1 
ATOM   4361 C CE1 . PHE C 1 150 ? 18.97433  45.30462 25.40684  1.000 29.47806  ? 146 PHE A CE1 1 
ATOM   4362 C CE2 . PHE C 1 150 ? 19.13510  45.66859 27.76971  1.000 30.15251  ? 146 PHE A CE2 1 
ATOM   4363 C CZ  . PHE C 1 150 ? 18.47330  45.13402 26.68428  1.000 24.65709  ? 146 PHE A CZ  1 
ATOM   4364 N N   . PRO C 1 151 ? 19.77976  49.65891 26.87785  1.000 22.34676  ? 147 PRO A N   1 
ATOM   4365 C CA  . PRO C 1 151 ? 18.91768  49.38361 25.72747  1.000 22.59620  ? 147 PRO A CA  1 
ATOM   4366 C C   . PRO C 1 151 ? 18.84403  50.62456 24.85749  1.000 25.48973  ? 147 PRO A C   1 
ATOM   4367 O O   . PRO C 1 151 ? 19.62103  51.55103 25.09252  1.000 21.36868  ? 147 PRO A O   1 
ATOM   4368 C CB  . PRO C 1 151 ? 17.57038  49.09183 26.37779  1.000 26.19749  ? 147 PRO A CB  1 
ATOM   4369 C CG  . PRO C 1 151 ? 17.56222  50.07678 27.54904  1.000 26.12945  ? 147 PRO A CG  1 
ATOM   4370 C CD  . PRO C 1 151 ? 18.99503  50.14156 28.03033  1.000 22.11635  ? 147 PRO A CD  1 
ATOM   4371 N N   . GLU C 1 152 ? 17.92289  50.65641 23.88971  1.000 24.60328  ? 148 GLU A N   1 
ATOM   4372 C CA  . GLU C 1 152 ? 17.62083  51.88884 23.18443  1.000 22.82662  ? 148 GLU A CA  1 
ATOM   4373 C C   . GLU C 1 152 ? 17.02301  52.89940 24.16251  1.000 24.62404  ? 148 GLU A C   1 
ATOM   4374 O O   . GLU C 1 152 ? 16.53583  52.52271 25.22687  1.000 25.73820  ? 148 GLU A O   1 
ATOM   4375 C CB  . GLU C 1 152 ? 16.63992  51.60745 22.03773  1.000 20.77648  ? 148 GLU A CB  1 
ATOM   4376 C CG  . GLU C 1 152 ? 17.24387  50.85193 20.86042  1.000 25.86662  ? 148 GLU A CG  1 
ATOM   4377 C CD  . GLU C 1 152 ? 17.78464  51.78759 19.77922  1.000 29.71537  ? 148 GLU A CD  1 
ATOM   4378 O OE1 . GLU C 1 152 ? 18.71556  52.58245 20.05856  1.000 28.86563  ? 148 GLU A OE1 1 
ATOM   4379 O OE2 . GLU C 1 152 ? 17.26004  51.73982 18.64690  1.000 32.10321  ? 148 GLU A OE2 1 
ATOM   4380 N N   . PRO C 1 153 ? 17.03324  54.20223 23.82060  1.000 25.47514  ? 149 PRO A N   1 
ATOM   4381 C CA  . PRO C 1 153 ? 17.63354  54.80640 22.62723  1.000 28.38536  ? 149 PRO A CA  1 
ATOM   4382 C C   . PRO C 1 153 ? 18.91226  55.60368 22.93037  1.000 26.11304  ? 149 PRO A C   1 
ATOM   4383 O O   . PRO C 1 153 ? 19.20117  55.88063 24.10594  1.000 20.77700  ? 149 PRO A O   1 
ATOM   4384 C CB  . PRO C 1 153 ? 16.53039  55.74100 22.15051  1.000 25.23062  ? 149 PRO A CB  1 
ATOM   4385 C CG  . PRO C 1 153 ? 15.96320  56.28715 23.48533  1.000 24.39365  ? 149 PRO A CG  1 
ATOM   4386 C CD  . PRO C 1 153 ? 16.14048  55.15594 24.50710  1.000 24.97857  ? 149 PRO A CD  1 
ATOM   4387 N N   . VAL C 1 154 ? 19.66745  55.93920 21.88207  1.000 24.13685  ? 150 VAL A N   1 
ATOM   4388 C CA  . VAL C 1 154 ? 20.69666  56.97440 21.93955  1.000 21.12118  ? 150 VAL A CA  1 
ATOM   4389 C C   . VAL C 1 154 ? 20.24175  58.11106 21.04403  1.000 26.98876  ? 150 VAL A C   1 
ATOM   4390 O O   . VAL C 1 154 ? 19.49153  57.90217 20.08276  1.000 21.36393  ? 150 VAL A O   1 
ATOM   4391 C CB  . VAL C 1 154 ? 22.09509  56.49608 21.48289  1.000 25.50594  ? 150 VAL A CB  1 
ATOM   4392 C CG1 . VAL C 1 154 ? 22.69544  55.48880 22.45405  1.000 23.02508  ? 150 VAL A CG1 1 
ATOM   4393 C CG2 . VAL C 1 154 ? 22.01488  55.92926 20.08464  1.000 25.92423  ? 150 VAL A CG2 1 
ATOM   4394 N N   . THR C 1 155 ? 20.69436  59.32175 21.35557  1.000 23.29389  ? 151 THR A N   1 
ATOM   4395 C CA  . THR C 1 155 ? 20.61396  60.41982 20.40065  1.000 27.76834  ? 151 THR A CA  1 
ATOM   4396 C C   . THR C 1 155 ? 22.02499  60.87415 20.05793  1.000 28.19214  ? 151 THR A C   1 
ATOM   4397 O O   . THR C 1 155 ? 22.93689  60.78639 20.88842  1.000 21.51499  ? 151 THR A O   1 
ATOM   4398 C CB  . THR C 1 155 ? 19.80077  61.60447 20.93017  1.000 28.57489  ? 151 THR A CB  1 
ATOM   4399 O OG1 . THR C 1 155 ? 20.37114  62.06603 22.15430  1.000 26.93686  ? 151 THR A OG1 1 
ATOM   4400 C CG2 . THR C 1 155 ? 18.33986  61.20823 21.15691  1.000 36.74249  ? 151 THR A CG2 1 
ATOM   4401 N N   . VAL C 1 156 ? 22.19829  61.35051 18.82269  1.000 19.76335  ? 152 VAL A N   1 
ATOM   4402 C CA  . VAL C 1 156 ? 23.48633  61.80351 18.31191  1.000 20.03139  ? 152 VAL A CA  1 
ATOM   4403 C C   . VAL C 1 156 ? 23.32176  63.21282 17.74428  1.000 21.90875  ? 152 VAL A C   1 
ATOM   4404 O O   . VAL C 1 156 ? 22.40892  63.46396 16.95407  1.000 23.41215  ? 152 VAL A O   1 
ATOM   4405 C CB  . VAL C 1 156 ? 24.03981  60.84861 17.23162  1.000 21.08501  ? 152 VAL A CB  1 
ATOM   4406 C CG1 . VAL C 1 156 ? 25.43607  61.26796 16.82307  1.000 21.96532  ? 152 VAL A CG1 1 
ATOM   4407 C CG2 . VAL C 1 156 ? 24.06640  59.38571 17.73766  1.000 19.57406  ? 152 VAL A CG2 1 
ATOM   4408 N N   . SER C 1 157 ? 24.19603  64.13090 18.14840  1.000 24.76558  ? 153 SER A N   1 
ATOM   4409 C CA  . SER C 1 157 ? 24.31793  65.42584 17.49057  1.000 24.99895  ? 153 SER A CA  1 
ATOM   4410 C C   . SER C 1 157 ? 25.77112  65.62564 17.09056  1.000 26.39536  ? 153 SER A C   1 
ATOM   4411 O O   . SER C 1 157 ? 26.65731  64.85942 17.48288  1.000 20.33471  ? 153 SER A O   1 
ATOM   4412 C CB  . SER C 1 157 ? 23.83814  66.58255 18.38319  1.000 21.71437  ? 153 SER A CB  1 
ATOM   4413 O OG  . SER C 1 157 ? 24.71560  66.79109 19.47473  1.000 29.78800  ? 153 SER A OG  1 
ATOM   4414 N N   . TRP C 1 158 ? 26.01779  66.65136 16.27556  1.000 24.60963  ? 154 TRP A N   1 
ATOM   4415 C CA  . TRP C 1 158 ? 27.36449  66.98439 15.82867  1.000 21.74709  ? 154 TRP A CA  1 
ATOM   4416 C C   . TRP C 1 158 ? 27.67384  68.42386 16.21349  1.000 26.27379  ? 154 TRP A C   1 
ATOM   4417 O O   . TRP C 1 158 ? 26.85194  69.32230 15.98536  1.000 28.58377  ? 154 TRP A O   1 
ATOM   4418 C CB  . TRP C 1 158 ? 27.51013  66.77569 14.31165  1.000 24.35213  ? 154 TRP A CB  1 
ATOM   4419 C CG  . TRP C 1 158 ? 27.67515  65.33692 13.94706  1.000 22.30356  ? 154 TRP A CG  1 
ATOM   4420 C CD1 . TRP C 1 158 ? 26.68682  64.45479 13.62120  1.000 20.43740  ? 154 TRP A CD1 1 
ATOM   4421 C CD2 . TRP C 1 158 ? 28.90342  64.60021 13.90089  1.000 20.03849  ? 154 TRP A CD2 1 
ATOM   4422 N NE1 . TRP C 1 158 ? 27.22541  63.21257 13.36592  1.000 19.23487  ? 154 TRP A NE1 1 
ATOM   4423 C CE2 . TRP C 1 158 ? 28.58292  63.27505 13.53887  1.000 23.26725  ? 154 TRP A CE2 1 
ATOM   4424 C CE3 . TRP C 1 158 ? 30.24188  64.92977 14.13413  1.000 24.14628  ? 154 TRP A CE3 1 
ATOM   4425 C CZ2 . TRP C 1 158 ? 29.55526  62.28635 13.38779  1.000 18.55237  ? 154 TRP A CZ2 1 
ATOM   4426 C CZ3 . TRP C 1 158 ? 31.21041  63.94023 13.98841  1.000 24.54401  ? 154 TRP A CZ3 1 
ATOM   4427 C CH2 . TRP C 1 158 ? 30.86194  62.63960 13.60892  1.000 19.17845  ? 154 TRP A CH2 1 
ATOM   4428 N N   . ASN C 1 159 ? 28.85418  68.63542 16.79684  1.000 27.85115  ? 155 ASN A N   1 
ATOM   4429 C CA  . ASN C 1 159 ? 29.29591  69.96205 17.23307  1.000 31.04862  ? 155 ASN A CA  1 
ATOM   4430 C C   . ASN C 1 159 ? 28.21733  70.64943 18.06340  1.000 30.51623  ? 155 ASN A C   1 
ATOM   4431 O O   . ASN C 1 159 ? 27.87605  71.81401 17.84916  1.000 31.03833  ? 155 ASN A O   1 
ATOM   4432 C CB  . ASN C 1 159 ? 29.71120  70.81654 16.03417  1.000 28.25186  ? 155 ASN A CB  1 
ATOM   4433 C CG  . ASN C 1 159 ? 30.97213  70.29782 15.38920  1.000 27.40325  ? 155 ASN A CG  1 
ATOM   4434 O OD1 . ASN C 1 159 ? 31.66474  69.48865 15.97988  1.000 26.07370  ? 155 ASN A OD1 1 
ATOM   4435 N ND2 . ASN C 1 159 ? 31.28072  70.76429 14.19189  1.000 29.40538  ? 155 ASN A ND2 1 
ATOM   4436 N N   . SER C 1 160 ? 27.65541  69.88549 19.00510  1.000 29.42720  ? 156 SER A N   1 
ATOM   4437 C CA  . SER C 1 160 ? 26.63532  70.35880 19.94555  1.000 25.61925  ? 156 SER A CA  1 
ATOM   4438 C C   . SER C 1 160 ? 25.40834  70.91994 19.23783  1.000 33.19328  ? 156 SER A C   1 
ATOM   4439 O O   . SER C 1 160 ? 24.75723  71.83639 19.74528  1.000 37.00681  ? 156 SER A O   1 
ATOM   4440 C CB  . SER C 1 160 ? 27.20395  71.39864 20.91688  1.000 31.64165  ? 156 SER A CB  1 
ATOM   4441 O OG  . SER C 1 160 ? 28.30147  70.87766 21.64340  1.000 30.51223  ? 156 SER A OG  1 
ATOM   4442 N N   . GLY C 1 161 ? 25.07275  70.37798 18.07169  1.000 29.30769  ? 157 GLY A N   1 
ATOM   4443 C CA  . GLY C 1 161 ? 23.90549  70.80342 17.33132  1.000 25.44885  ? 157 GLY A CA  1 
ATOM   4444 C C   . GLY C 1 161 ? 24.16857  71.83332 16.24914  1.000 35.81434  ? 157 GLY A C   1 
ATOM   4445 O O   . GLY C 1 161 ? 23.27483  72.08383 15.42827  1.000 35.22184  ? 157 GLY A O   1 
ATOM   4446 N N   . ALA C 1 162 ? 25.36026  72.43650 16.21954  1.000 35.80951  ? 158 ALA A N   1 
ATOM   4447 C CA  . ALA C 1 162 ? 25.66828  73.43217 15.19682  1.000 32.04934  ? 158 ALA A CA  1 
ATOM   4448 C C   . ALA C 1 162 ? 25.82800  72.81756 13.81512  1.000 38.21994  ? 158 ALA A C   1 
ATOM   4449 O O   . ALA C 1 162 ? 25.68101  73.52339 12.81546  1.000 40.07187  ? 158 ALA A O   1 
ATOM   4450 C CB  . ALA C 1 162 ? 26.93910  74.19331 15.56983  1.000 30.00876  ? 158 ALA A CB  1 
ATOM   4451 N N   . LEU C 1 163 ? 26.12229  71.52610 13.72666  1.000 32.33307  ? 159 LEU A N   1 
ATOM   4452 C CA  . LEU C 1 163 ? 26.30346  70.85665 12.44443  1.000 27.02322  ? 159 LEU A CA  1 
ATOM   4453 C C   . LEU C 1 163 ? 25.12546  69.91684 12.22207  1.000 33.12468  ? 159 LEU A C   1 
ATOM   4454 O O   . LEU C 1 163 ? 24.98157  68.91044 12.92587  1.000 30.18303  ? 159 LEU A O   1 
ATOM   4455 C CB  . LEU C 1 163 ? 27.63529  70.11393 12.41458  1.000 28.01379  ? 159 LEU A CB  1 
ATOM   4456 C CG  . LEU C 1 163 ? 27.93313  69.31633 11.14821  1.000 33.79407  ? 159 LEU A CG  1 
ATOM   4457 C CD1 . LEU C 1 163 ? 27.86548  70.21873 9.91264   1.000 31.81394  ? 159 LEU A CD1 1 
ATOM   4458 C CD2 . LEU C 1 163 ? 29.30493  68.66954 11.27340  1.000 24.94937  ? 159 LEU A CD2 1 
ATOM   4459 N N   . THR C 1 164 ? 24.26310  70.26783 11.26772  1.000 29.82836  ? 160 THR A N   1 
ATOM   4460 C CA  . THR C 1 164 ? 23.10915  69.44915 10.91116  1.000 27.30948  ? 160 THR A CA  1 
ATOM   4461 C C   . THR C 1 164 ? 23.03487  69.14226 9.42871   1.000 27.26226  ? 160 THR A C   1 
ATOM   4462 O O   . THR C 1 164 ? 22.43871  68.12426 9.05416   1.000 30.32752  ? 160 THR A O   1 
ATOM   4463 C CB  . THR C 1 164 ? 21.79781  70.13555 11.32607  1.000 36.20277  ? 160 THR A CB  1 
ATOM   4464 O OG1 . THR C 1 164 ? 21.63803  71.34486 10.57726  1.000 42.73454  ? 160 THR A OG1 1 
ATOM   4465 C CG2 . THR C 1 164 ? 21.80331  70.47259 12.81390  1.000 33.72593  ? 160 THR A CG2 1 
ATOM   4466 N N   . SER C 1 165 ? 23.62306  69.97219 8.57695   1.000 29.89106  ? 161 SER A N   1 
ATOM   4467 C CA  . SER C 1 165 ? 23.54401  69.74932 7.14404   1.000 32.56258  ? 161 SER A CA  1 
ATOM   4468 C C   . SER C 1 165 ? 24.39266  68.54711 6.74756   1.000 29.63692  ? 161 SER A C   1 
ATOM   4469 O O   . SER C 1 165 ? 25.58718  68.48666 7.05800   1.000 35.07839  ? 161 SER A O   1 
ATOM   4470 C CB  . SER C 1 165 ? 24.00941  71.00307 6.39970   1.000 38.84711  ? 161 SER A CB  1 
ATOM   4471 O OG  . SER C 1 165 ? 23.91111  70.81247 5.00540   1.000 44.37363  ? 161 SER A OG  1 
ATOM   4472 N N   . GLY C 1 166 ? 23.77239  67.59047 6.06011   1.000 30.26918  ? 162 GLY A N   1 
ATOM   4473 C CA  . GLY C 1 166 ? 24.46930  66.41790 5.56641   1.000 27.54822  ? 162 GLY A CA  1 
ATOM   4474 C C   . GLY C 1 166 ? 24.66727  65.30549 6.57878   1.000 32.35885  ? 162 GLY A C   1 
ATOM   4475 O O   . GLY C 1 166 ? 25.39799  64.35280 6.28060   1.000 27.57065  ? 162 GLY A O   1 
ATOM   4476 N N   . VAL C 1 167 ? 24.05379  65.39871 7.76462   1.000 25.23685  ? 163 VAL A N   1 
ATOM   4477 C CA  . VAL C 1 167 ? 24.18801  64.36386 8.79563   1.000 24.92031  ? 163 VAL A CA  1 
ATOM   4478 C C   . VAL C 1 167 ? 23.23998  63.21209 8.49401   1.000 25.38032  ? 163 VAL A C   1 
ATOM   4479 O O   . VAL C 1 167 ? 22.06261  63.42054 8.18803   1.000 28.92465  ? 163 VAL A O   1 
ATOM   4480 C CB  . VAL C 1 167 ? 23.90406  64.94184 10.19134  1.000 23.29870  ? 163 VAL A CB  1 
ATOM   4481 C CG1 . VAL C 1 167 ? 23.94450  63.81216 11.26091  1.000 16.92474  ? 163 VAL A CG1 1 
ATOM   4482 C CG2 . VAL C 1 167 ? 24.89391  66.04231 10.51857  1.000 20.63190  ? 163 VAL A CG2 1 
ATOM   4483 N N   . HIS C 1 168 ? 23.73938  61.98729 8.59200   1.000 23.60531  ? 164 HIS A N   1 
ATOM   4484 C CA  . HIS C 1 168 ? 22.87726  60.81049 8.57118   1.000 26.30705  ? 164 HIS A CA  1 
ATOM   4485 C C   . HIS C 1 168 ? 23.15810  59.98756 9.81786   1.000 23.07151  ? 164 HIS A C   1 
ATOM   4486 O O   . HIS C 1 168 ? 24.24962  59.42639 9.95667   1.000 19.76276  ? 164 HIS A O   1 
ATOM   4487 C CB  . HIS C 1 168 ? 23.09841  59.96663 7.31556   1.000 24.63834  ? 164 HIS A CB  1 
ATOM   4488 C CG  . HIS C 1 168 ? 22.65460  60.64064 6.05507   1.000 29.44759  ? 164 HIS A CG  1 
ATOM   4489 N ND1 . HIS C 1 168 ? 21.33068  60.92380 5.79112   1.000 36.08124  ? 164 HIS A ND1 1 
ATOM   4490 C CD2 . HIS C 1 168 ? 23.35733  61.09286 4.98903   1.000 34.13519  ? 164 HIS A CD2 1 
ATOM   4491 C CE1 . HIS C 1 168 ? 21.23736  61.51882 4.61340   1.000 39.72356  ? 164 HIS A CE1 1 
ATOM   4492 N NE2 . HIS C 1 168 ? 22.45159  61.62745 4.10320   1.000 28.69881  ? 164 HIS A NE2 1 
ATOM   4493 N N   . THR C 1 169 ? 22.17237  59.89918 10.70475  1.000 21.80592  ? 165 THR A N   1 
ATOM   4494 C CA  . THR C 1 169 ? 22.23617  59.01369 11.86366  1.000 21.30618  ? 165 THR A CA  1 
ATOM   4495 C C   . THR C 1 169 ? 21.33155  57.82027 11.57280  1.000 22.97417  ? 165 THR A C   1 
ATOM   4496 O O   . THR C 1 169 ? 20.10657  57.96487 11.49523  1.000 26.43384  ? 165 THR A O   1 
ATOM   4497 C CB  . THR C 1 169 ? 21.82469  59.74394 13.14232  1.000 22.22731  ? 165 THR A CB  1 
ATOM   4498 O OG1 . THR C 1 169 ? 22.73817  60.82282 13.39685  1.000 24.27656  ? 165 THR A OG1 1 
ATOM   4499 C CG2 . THR C 1 169 ? 21.85738  58.79629 14.33050  1.000 28.44413  ? 165 THR A CG2 1 
ATOM   4500 N N   . PHE C 1 170 ? 21.93365  56.65626 11.39572  1.000 22.61400  ? 166 PHE A N   1 
ATOM   4501 C CA  . PHE C 1 170 ? 21.22847  55.44423 10.99666  1.000 22.68675  ? 166 PHE A CA  1 
ATOM   4502 C C   . PHE C 1 170 ? 20.43797  54.83192 12.15526  1.000 33.04515  ? 166 PHE A C   1 
ATOM   4503 O O   . PHE C 1 170 ? 20.86938  54.90294 13.30951  1.000 27.15986  ? 166 PHE A O   1 
ATOM   4504 C CB  . PHE C 1 170 ? 22.21659  54.41865 10.47867  1.000 19.79218  ? 166 PHE A CB  1 
ATOM   4505 C CG  . PHE C 1 170 ? 22.80106  54.77876 9.15270   1.000 27.21368  ? 166 PHE A CG  1 
ATOM   4506 C CD1 . PHE C 1 170 ? 22.13177  54.46027 7.98320   1.000 24.08252  ? 166 PHE A CD1 1 
ATOM   4507 C CD2 . PHE C 1 170 ? 24.00118  55.46124 9.07211   1.000 23.85351  ? 166 PHE A CD2 1 
ATOM   4508 C CE1 . PHE C 1 170 ? 22.66158  54.80333 6.75274   1.000 26.21984  ? 166 PHE A CE1 1 
ATOM   4509 C CE2 . PHE C 1 170 ? 24.53913  55.80408 7.83939   1.000 27.89710  ? 166 PHE A CE2 1 
ATOM   4510 C CZ  . PHE C 1 170 ? 23.87012  55.47605 6.68199   1.000 23.78251  ? 166 PHE A CZ  1 
ATOM   4511 N N   . PRO C 1 171 ? 19.28572  54.21123 11.86258  1.000 30.78214  ? 167 PRO A N   1 
ATOM   4512 C CA  . PRO C 1 171 ? 18.60707  53.39044 12.87873  1.000 27.74165  ? 167 PRO A CA  1 
ATOM   4513 C C   . PRO C 1 171 ? 19.56148  52.36093 13.45040  1.000 26.07468  ? 167 PRO A C   1 
ATOM   4514 O O   . PRO C 1 171 ? 20.42901  51.83588 12.74670  1.000 25.15086  ? 167 PRO A O   1 
ATOM   4515 C CB  . PRO C 1 171 ? 17.46931  52.71235 12.09884  1.000 26.61651  ? 167 PRO A CB  1 
ATOM   4516 C CG  . PRO C 1 171 ? 17.24184  53.58183 10.90484  1.000 26.18077  ? 167 PRO A CG  1 
ATOM   4517 C CD  . PRO C 1 171 ? 18.57641  54.19890 10.56480  1.000 23.40532  ? 167 PRO A CD  1 
ATOM   4518 N N   . ALA C 1 172 ? 19.39773  52.06787 14.73791  1.000 19.07926  ? 168 ALA A N   1 
ATOM   4519 C CA  . ALA C 1 172 ? 20.24563  51.07079 15.36726  1.000 20.06942  ? 168 ALA A CA  1 
ATOM   4520 C C   . ALA C 1 172 ? 19.89913  49.67055 14.87436  1.000 18.08722  ? 168 ALA A C   1 
ATOM   4521 O O   . ALA C 1 172 ? 18.75604  49.36522 14.53907  1.000 23.04084  ? 168 ALA A O   1 
ATOM   4522 C CB  . ALA C 1 172 ? 20.10068  51.13177 16.89228  1.000 20.49744  ? 168 ALA A CB  1 
ATOM   4523 N N   . VAL C 1 173 ? 20.89872  48.80728 14.85119  1.000 19.71139  ? 169 VAL A N   1 
ATOM   4524 C CA  . VAL C 1 173 ? 20.69692  47.38493 14.61233  1.000 25.37170  ? 169 VAL A CA  1 
ATOM   4525 C C   . VAL C 1 173 ? 20.93477  46.63746 15.92096  1.000 27.68260  ? 169 VAL A C   1 
ATOM   4526 O O   . VAL C 1 173 ? 21.85904  46.96189 16.68196  1.000 29.81575  ? 169 VAL A O   1 
ATOM   4527 C CB  . VAL C 1 173 ? 21.61488  46.85387 13.49183  1.000 29.31484  ? 169 VAL A CB  1 
ATOM   4528 C CG1 . VAL C 1 173 ? 21.31922  47.58084 12.18275  1.000 28.65740  ? 169 VAL A CG1 1 
ATOM   4529 C CG2 . VAL C 1 173 ? 23.06872  47.00873 13.86464  1.000 28.19328  ? 169 VAL A CG2 1 
ATOM   4530 N N   . LEU C 1 174 ? 20.07766  45.66185 16.20111  1.000 25.41403  ? 170 LEU A N   1 
ATOM   4531 C CA  . LEU C 1 174 ? 20.30139  44.75888 17.32792  1.000 25.58970  ? 170 LEU A CA  1 
ATOM   4532 C C   . LEU C 1 174 ? 21.32306  43.71650 16.90227  1.000 33.99515  ? 170 LEU A C   1 
ATOM   4533 O O   . LEU C 1 174 ? 21.09176  42.97273 15.94186  1.000 31.20425  ? 170 LEU A O   1 
ATOM   4534 C CB  . LEU C 1 174 ? 18.99186  44.09876 17.75619  1.000 26.75475  ? 170 LEU A CB  1 
ATOM   4535 C CG  . LEU C 1 174 ? 18.97198  43.27092 19.05078  1.000 37.38495  ? 170 LEU A CG  1 
ATOM   4536 C CD1 . LEU C 1 174 ? 19.43039  44.09679 20.24142  1.000 28.03992  ? 170 LEU A CD1 1 
ATOM   4537 C CD2 . LEU C 1 174 ? 17.57651  42.72135 19.30764  1.000 30.22355  ? 170 LEU A CD2 1 
ATOM   4538 N N   . GLN C 1 175 ? 22.46038  43.67808 17.58667  1.000 26.73073  ? 171 GLN A N   1 
ATOM   4539 C CA  . GLN C 1 175 ? 23.48598  42.72053 17.21893  1.000 31.74551  ? 171 GLN A CA  1 
ATOM   4540 C C   . GLN C 1 175 ? 23.15136  41.35003 17.79906  1.000 36.17363  ? 171 GLN A C   1 
ATOM   4541 O O   . GLN C 1 175 ? 22.23474  41.19148 18.60915  1.000 35.97623  ? 171 GLN A O   1 
ATOM   4542 C CB  . GLN C 1 175 ? 24.86009  43.18936 17.69140  1.000 39.68649  ? 171 GLN A CB  1 
ATOM   4543 C CG  . GLN C 1 175 ? 25.35170  44.47154 17.01921  1.000 36.57565  ? 171 GLN A CG  1 
ATOM   4544 C CD  . GLN C 1 175 ? 26.50245  45.11469 17.77939  1.000 40.99261  ? 171 GLN A CD  1 
ATOM   4545 O OE1 . GLN C 1 175 ? 27.54535  45.42116 17.20409  1.000 38.51624  ? 171 GLN A OE1 1 
ATOM   4546 N NE2 . GLN C 1 175 ? 26.31683  45.31531 19.08607  1.000 32.66707  ? 171 GLN A NE2 1 
ATOM   4547 N N   . SER C 1 176 ? 23.89937  40.34180 17.35065  1.000 41.55044  ? 172 SER A N   1 
ATOM   4548 C CA  . SER C 1 176 ? 23.66452  38.98485 17.82332  1.000 49.22836  ? 172 SER A CA  1 
ATOM   4549 C C   . SER C 1 176 ? 24.00859  38.84105 19.29684  1.000 40.90003  ? 172 SER A C   1 
ATOM   4550 O O   . SER C 1 176 ? 23.47751  37.95006 19.96583  1.000 43.91134  ? 172 SER A O   1 
ATOM   4551 C CB  . SER C 1 176 ? 24.46367  37.98600 16.97471  1.000 45.23061  ? 172 SER A CB  1 
ATOM   4552 O OG  . SER C 1 176 ? 25.84566  38.32552 16.93351  1.000 54.81995  ? 172 SER A OG  1 
ATOM   4553 N N   . SER C 1 177 ? 24.86003  39.72045 19.81944  1.000 39.12282  ? 173 SER A N   1 
ATOM   4554 C CA  . SER C 1 177 ? 25.16697  39.74641 21.24102  1.000 31.62609  ? 173 SER A CA  1 
ATOM   4555 C C   . SER C 1 177 ? 23.99487  40.19795 22.10242  1.000 33.27699  ? 173 SER A C   1 
ATOM   4556 O O   . SER C 1 177 ? 24.05514  40.04365 23.32582  1.000 35.14726  ? 173 SER A O   1 
ATOM   4557 C CB  . SER C 1 177 ? 26.35976  40.66891 21.48612  1.000 35.80925  ? 173 SER A CB  1 
ATOM   4558 O OG  . SER C 1 177 ? 26.11634  41.95568 20.94107  1.000 37.55525  ? 173 SER A OG  1 
ATOM   4559 N N   . GLY C 1 178 ? 22.94015  40.74849 21.51541  1.000 34.83853  ? 174 GLY A N   1 
ATOM   4560 C CA  . GLY C 1 178 ? 21.90123  41.37897 22.30166  1.000 30.84650  ? 174 GLY A CA  1 
ATOM   4561 C C   . GLY C 1 178 ? 22.12241  42.85130 22.58349  1.000 27.43592  ? 174 GLY A C   1 
ATOM   4562 O O   . GLY C 1 178 ? 21.27683  43.47311 23.24003  1.000 25.69603  ? 174 GLY A O   1 
ATOM   4563 N N   . LEU C 1 179 ? 23.23212  43.42420 22.12733  1.000 25.72136  ? 175 LEU A N   1 
ATOM   4564 C CA  . LEU C 1 179 ? 23.51728  44.84338 22.28868  1.000 21.26632  ? 175 LEU A CA  1 
ATOM   4565 C C   . LEU C 1 179 ? 23.25417  45.59583 20.98074  1.000 29.12627  ? 175 LEU A C   1 
ATOM   4566 O O   . LEU C 1 179 ? 23.29878  45.01952 19.88999  1.000 30.92960  ? 175 LEU A O   1 
ATOM   4567 C CB  . LEU C 1 179 ? 24.96823  45.04177 22.72749  1.000 25.24484  ? 175 LEU A CB  1 
ATOM   4568 C CG  . LEU C 1 179 ? 25.38567  44.27485 23.98628  1.000 25.00227  ? 175 LEU A CG  1 
ATOM   4569 C CD1 . LEU C 1 179 ? 26.87767  44.45796 24.26046  1.000 24.70916  ? 175 LEU A CD1 1 
ATOM   4570 C CD2 . LEU C 1 179 ? 24.55192  44.67676 25.20642  1.000 22.57808  ? 175 LEU A CD2 1 
ATOM   4571 N N   . TYR C 1 180 ? 22.97980  46.89184 21.09571  1.000 22.51239  ? 176 TYR A N   1 
ATOM   4572 C CA  . TYR C 1 180 ? 22.66915  47.70510 19.92701  1.000 22.67732  ? 176 TYR A CA  1 
ATOM   4573 C C   . TYR C 1 180 ? 23.90995  48.43059 19.42940  1.000 26.31055  ? 176 TYR A C   1 
ATOM   4574 O O   . TYR C 1 180 ? 24.86488  48.67785 20.17744  1.000 21.14542  ? 176 TYR A O   1 
ATOM   4575 C CB  . TYR C 1 180 ? 21.58327  48.73421 20.23219  1.000 19.30410  ? 176 TYR A CB  1 
ATOM   4576 C CG  . TYR C 1 180 ? 20.24780  48.13900 20.58126  1.000 29.85759  ? 176 TYR A CG  1 
ATOM   4577 C CD1 . TYR C 1 180 ? 19.29824  47.87985 19.59160  1.000 24.04736  ? 176 TYR A CD1 1 
ATOM   4578 C CD2 . TYR C 1 180 ? 19.92155  47.85030 21.90818  1.000 25.34600  ? 176 TYR A CD2 1 
ATOM   4579 C CE1 . TYR C 1 180 ? 18.06004  47.33885 19.91259  1.000 25.87940  ? 176 TYR A CE1 1 
ATOM   4580 C CE2 . TYR C 1 180 ? 18.69295  47.30519 22.23947  1.000 26.04567  ? 176 TYR A CE2 1 
ATOM   4581 C CZ  . TYR C 1 180 ? 17.76575  47.05168 21.23434  1.000 37.46343  ? 176 TYR A CZ  1 
ATOM   4582 O OH  . TYR C 1 180 ? 16.54489  46.51588 21.56667  1.000 33.74536  ? 176 TYR A OH  1 
ATOM   4583 N N   . SER C 1 181 ? 23.87335  48.79962 18.15097  1.000 24.70901  ? 177 SER A N   1 
ATOM   4584 C CA  . SER C 1 181 ? 24.96798  49.55162 17.55962  1.000 23.51769  ? 177 SER A CA  1 
ATOM   4585 C C   . SER C 1 181 ? 24.42667  50.39385 16.40997  1.000 25.90404  ? 177 SER A C   1 
ATOM   4586 O O   . SER C 1 181 ? 23.48448  49.98733 15.71979  1.000 27.78161  ? 177 SER A O   1 
ATOM   4587 C CB  . SER C 1 181 ? 26.07953  48.59849 17.11016  1.000 21.24638  ? 177 SER A CB  1 
ATOM   4588 O OG  . SER C 1 181 ? 26.93640  49.18900 16.15697  1.000 31.71133  ? 177 SER A OG  1 
ATOM   4589 N N   . LEU C 1 182 ? 24.99535  51.58507 16.23504  1.000 22.87555  ? 178 LEU A N   1 
ATOM   4590 C CA  . LEU C 1 182 ? 24.61591  52.42857 15.11438  1.000 25.19368  ? 178 LEU A CA  1 
ATOM   4591 C C   . LEU C 1 182 ? 25.80227  53.27523 14.68249  1.000 25.11780  ? 178 LEU A C   1 
ATOM   4592 O O   . LEU C 1 182 ? 26.80536  53.39133 15.38678  1.000 19.05272  ? 178 LEU A O   1 
ATOM   4593 C CB  . LEU C 1 182 ? 23.41639  53.31228 15.45109  1.000 24.94018  ? 178 LEU A CB  1 
ATOM   4594 C CG  . LEU C 1 182 ? 23.41445  54.42364 16.49451  1.000 28.06550  ? 178 LEU A CG  1 
ATOM   4595 C CD1 . LEU C 1 182 ? 24.18045  55.67174 16.04176  1.000 24.43181  ? 178 LEU A CD1 1 
ATOM   4596 C CD2 . LEU C 1 182 ? 21.95037  54.76452 16.74761  1.000 27.09556  ? 178 LEU A CD2 1 
ATOM   4597 N N   . SER C 1 183 ? 25.65847  53.88478 13.51304  1.000 18.32552  ? 179 SER A N   1 
ATOM   4598 C CA  . SER C 1 183 ? 26.61000  54.86175 13.02068  1.000 23.77908  ? 179 SER A CA  1 
ATOM   4599 C C   . SER C 1 183 ? 25.89358  56.16760 12.73590  1.000 22.43047  ? 179 SER A C   1 
ATOM   4600 O O   . SER C 1 183 ? 24.71118  56.18221 12.38096  1.000 21.78564  ? 179 SER A O   1 
ATOM   4601 C CB  . SER C 1 183 ? 27.30817  54.38037 11.75396  1.000 25.14273  ? 179 SER A CB  1 
ATOM   4602 O OG  . SER C 1 183 ? 28.34496  53.48885 12.09743  1.000 31.92130  ? 179 SER A OG  1 
ATOM   4603 N N   . SER C 1 184 ? 26.62485  57.26296 12.92085  1.000 18.93410  ? 180 SER A N   1 
ATOM   4604 C CA  . SER C 1 184 ? 26.20868  58.58887 12.49887  1.000 20.36315  ? 180 SER A CA  1 
ATOM   4605 C C   . SER C 1 184 ? 27.31769  59.11842 11.61420  1.000 20.69511  ? 180 SER A C   1 
ATOM   4606 O O   . SER C 1 184 ? 28.49576  58.99711 11.96507  1.000 21.04515  ? 180 SER A O   1 
ATOM   4607 C CB  . SER C 1 184 ? 25.98370  59.52575 13.68502  1.000 20.45658  ? 180 SER A CB  1 
ATOM   4608 O OG  . SER C 1 184 ? 25.48124  60.77766 13.23873  1.000 22.37921  ? 180 SER A OG  1 
ATOM   4609 N N   . VAL C 1 185 ? 26.94930  59.68152 10.46706  1.000 19.46427  ? 181 VAL A N   1 
ATOM   4610 C CA  . VAL C 1 185 ? 27.92940  60.12108 9.48393   1.000 21.18904  ? 181 VAL A CA  1 
ATOM   4611 C C   . VAL C 1 185 ? 27.54110  61.50351 8.98757   1.000 22.61621  ? 181 VAL A C   1 
ATOM   4612 O O   . VAL C 1 185 ? 26.39058  61.92548 9.08584   1.000 22.43109  ? 181 VAL A O   1 
ATOM   4613 C CB  . VAL C 1 185 ? 28.06526  59.14591 8.29508   1.000 17.43018  ? 181 VAL A CB  1 
ATOM   4614 C CG1 . VAL C 1 185 ? 28.57374  57.78103 8.76534   1.000 22.39731  ? 181 VAL A CG1 1 
ATOM   4615 C CG2 . VAL C 1 185 ? 26.75079  59.01937 7.52789   1.000 20.33382  ? 181 VAL A CG2 1 
ATOM   4616 N N   . VAL C 1 186 ? 28.53113  62.22282 8.47715   1.000 21.29205  ? 182 VAL A N   1 
ATOM   4617 C CA  . VAL C 1 186 ? 28.28399  63.52223 7.86699   1.000 24.30611  ? 182 VAL A CA  1 
ATOM   4618 C C   . VAL C 1 186 ? 29.25455  63.69489 6.70311   1.000 23.42688  ? 182 VAL A C   1 
ATOM   4619 O O   . VAL C 1 186 ? 30.41948  63.29257 6.78276   1.000 22.55356  ? 182 VAL A O   1 
ATOM   4620 C CB  . VAL C 1 186 ? 28.40257  64.66032 8.90785   1.000 27.31476  ? 182 VAL A CB  1 
ATOM   4621 C CG1 . VAL C 1 186 ? 29.76756  64.65390 9.55548   1.000 29.25853  ? 182 VAL A CG1 1 
ATOM   4622 C CG2 . VAL C 1 186 ? 28.09218  66.02256 8.26404   1.000 27.41016  ? 182 VAL A CG2 1 
ATOM   4623 N N   . THR C 1 187 ? 28.75943  64.24800 5.59696   1.000 23.04729  ? 183 THR A N   1 
ATOM   4624 C CA  . THR C 1 187 ? 29.62415  64.63297 4.48886   1.000 24.31091  ? 183 THR A CA  1 
ATOM   4625 C C   . THR C 1 187 ? 29.95866  66.11228 4.62634   1.000 27.56876  ? 183 THR A C   1 
ATOM   4626 O O   . THR C 1 187 ? 29.07867  66.93772 4.88939   1.000 26.56753  ? 183 THR A O   1 
ATOM   4627 C CB  . THR C 1 187 ? 28.98701  64.34910 3.13224   1.000 25.02475  ? 183 THR A CB  1 
ATOM   4628 O OG1 . THR C 1 187 ? 27.65752  64.87655 3.11439   1.000 28.84637  ? 183 THR A OG1 1 
ATOM   4629 C CG2 . THR C 1 187 ? 28.95139  62.83961 2.86367   1.000 26.33781  ? 183 THR A CG2 1 
ATOM   4630 N N   . VAL C 1 188 ? 31.23732  66.42654 4.47401   1.000 24.09213  ? 184 VAL A N   1 
ATOM   4631 C CA  . VAL C 1 188 ? 31.77305  67.77505 4.63356   1.000 29.60969  ? 184 VAL A CA  1 
ATOM   4632 C C   . VAL C 1 188 ? 32.70444  68.03517 3.45988   1.000 30.25371  ? 184 VAL A C   1 
ATOM   4633 O O   . VAL C 1 188 ? 33.18993  67.08876 2.82137   1.000 22.93123  ? 184 VAL A O   1 
ATOM   4634 C CB  . VAL C 1 188 ? 32.53060  67.92820 5.97135   1.000 31.43311  ? 184 VAL A CB  1 
ATOM   4635 C CG1 . VAL C 1 188 ? 31.60248  67.59486 7.17282   1.000 24.10557  ? 184 VAL A CG1 1 
ATOM   4636 C CG2 . VAL C 1 188 ? 33.76666  67.02306 5.97239   1.000 27.61944  ? 184 VAL A CG2 1 
ATOM   4637 N N   . PRO C 1 189 ? 32.98221  69.29984 3.15314   1.000 29.23176  ? 185 PRO A N   1 
ATOM   4638 C CA  . PRO C 1 189 ? 34.05328  69.59493 2.18921   1.000 34.54759  ? 185 PRO A CA  1 
ATOM   4639 C C   . PRO C 1 189 ? 35.38943  69.05294 2.68192   1.000 29.70230  ? 185 PRO A C   1 
ATOM   4640 O O   . PRO C 1 189 ? 35.74124  69.20360 3.85405   1.000 29.85357  ? 185 PRO A O   1 
ATOM   4641 C CB  . PRO C 1 189 ? 34.05792  71.12890 2.11633   1.000 31.62834  ? 185 PRO A CB  1 
ATOM   4642 C CG  . PRO C 1 189 ? 32.69051  71.53784 2.57596   1.000 38.14502  ? 185 PRO A CG  1 
ATOM   4643 C CD  . PRO C 1 189 ? 32.29703  70.51923 3.61046   1.000 24.86706  ? 185 PRO A CD  1 
ATOM   4644 N N   . SER C 1 190 ? 36.12785  68.40295 1.76909   1.000 31.16866  ? 186 SER A N   1 
ATOM   4645 C CA  . SER C 1 190 ? 37.44971  67.86327 2.09878   1.000 28.23296  ? 186 SER A CA  1 
ATOM   4646 C C   . SER C 1 190 ? 38.41964  68.95120 2.53705   1.000 35.09236  ? 186 SER A C   1 
ATOM   4647 O O   . SER C 1 190 ? 39.35902  68.67664 3.29386   1.000 37.15151  ? 186 SER A O   1 
ATOM   4648 C CB  . SER C 1 190 ? 38.04310  67.12677 0.89550   1.000 43.14769  ? 186 SER A CB  1 
ATOM   4649 O OG  . SER C 1 190 ? 37.12742  66.20739 0.32452   1.000 44.49566  ? 186 SER A OG  1 
ATOM   4650 N N   . SER C 1 191 ? 38.23335  70.18278 2.05501   1.000 33.88491  ? 187 SER A N   1 
ATOM   4651 C CA  . SER C 1 191 ? 39.14067  71.26341 2.42376   1.000 36.53905  ? 187 SER A CA  1 
ATOM   4652 C C   . SER C 1 191 ? 38.96466  71.71737 3.86879   1.000 45.39426  ? 187 SER A C   1 
ATOM   4653 O O   . SER C 1 191 ? 39.82515  72.44029 4.38021   1.000 48.36075  ? 187 SER A O   1 
ATOM   4654 C CB  . SER C 1 191 ? 38.95846  72.45455 1.47906   1.000 42.96648  ? 187 SER A CB  1 
ATOM   4655 O OG  . SER C 1 191 ? 37.68032  73.05668 1.62444   1.000 37.62514  ? 187 SER A OG  1 
ATOM   4656 N N   . SER C 1 192 ? 37.88901  71.31020 4.54140   1.000 45.41265  ? 188 SER A N   1 
ATOM   4657 C CA  . SER C 1 192 ? 37.64635  71.72185 5.91972   1.000 48.25350  ? 188 SER A CA  1 
ATOM   4658 C C   . SER C 1 192 ? 38.26078  70.77766 6.94468   1.000 43.59735  ? 188 SER A C   1 
ATOM   4659 O O   . SER C 1 192 ? 38.30299  71.12428 8.12960   1.000 48.03063  ? 188 SER A O   1 
ATOM   4660 C CB  . SER C 1 192 ? 36.14283  71.82712 6.18129   1.000 45.24511  ? 188 SER A CB  1 
ATOM   4661 O OG  . SER C 1 192 ? 35.57841  70.53109 6.29400   1.000 42.67498  ? 188 SER A OG  1 
ATOM   4662 N N   . LEU C 1 193 ? 38.74457  69.60722 6.51617   1.000 37.38659  ? 189 LEU A N   1 
ATOM   4663 C CA  . LEU C 1 193 ? 39.28089  68.61722 7.43980   1.000 42.00622  ? 189 LEU A CA  1 
ATOM   4664 C C   . LEU C 1 193 ? 40.44918  69.14446 8.25969   1.000 52.88437  ? 189 LEU A C   1 
ATOM   4665 O O   . LEU C 1 193 ? 40.78583  68.54613 9.28372   1.000 44.78203  ? 189 LEU A O   1 
ATOM   4666 C CB  . LEU C 1 193 ? 39.71594  67.36790 6.67602   1.000 37.46519  ? 189 LEU A CB  1 
ATOM   4667 C CG  . LEU C 1 193 ? 38.57759  66.60295 6.00568   1.000 35.69035  ? 189 LEU A CG  1 
ATOM   4668 C CD1 . LEU C 1 193 ? 39.07428  65.32106 5.33337   1.000 36.37374  ? 189 LEU A CD1 1 
ATOM   4669 C CD2 . LEU C 1 193 ? 37.48048  66.30615 7.02613   1.000 33.37120  ? 189 LEU A CD2 1 
ATOM   4670 N N   . GLY C 1 194 ? 41.07574  70.23980 7.84279   1.000 52.85617  ? 190 GLY A N   1 
ATOM   4671 C CA  . GLY C 1 194 ? 42.17451  70.79362 8.60842   1.000 54.28427  ? 190 GLY A CA  1 
ATOM   4672 C C   . GLY C 1 194 ? 41.74426  71.85752 9.59828   1.000 56.22231  ? 190 GLY A C   1 
ATOM   4673 O O   . GLY C 1 194 ? 42.24519  71.91192 10.72427  1.000 55.62044  ? 190 GLY A O   1 
ATOM   4674 N N   . THR C 1 195 ? 40.81033  72.71337 9.19452   1.000 52.34295  ? 191 THR A N   1 
ATOM   4675 C CA  . THR C 1 195 ? 40.39761  73.80848 10.06058  1.000 56.44915  ? 191 THR A CA  1 
ATOM   4676 C C   . THR C 1 195 ? 39.26654  73.41237 11.01029  1.000 59.13045  ? 191 THR A C   1 
ATOM   4677 O O   . THR C 1 195 ? 39.37003  73.62453 12.22508  1.000 60.83276  ? 191 THR A O   1 
ATOM   4678 C CB  . THR C 1 195 ? 39.98346  75.01050 9.20763   1.000 55.23411  ? 191 THR A CB  1 
ATOM   4679 O OG1 . THR C 1 195 ? 39.04127  74.58724 8.21217   1.000 65.49067  ? 191 THR A OG1 1 
ATOM   4680 C CG2 . THR C 1 195 ? 41.19992  75.61555 8.52843   1.000 53.36148  ? 191 THR A CG2 1 
ATOM   4681 N N   . GLN C 1 196 ? 38.19785  72.81832 10.47947  1.000 52.62992  ? 192 GLN A N   1 
ATOM   4682 C CA  . GLN C 1 196 ? 36.96939  72.61615 11.23928  1.000 42.05563  ? 192 GLN A CA  1 
ATOM   4683 C C   . GLN C 1 196 ? 37.06996  71.40249 12.16425  1.000 41.34073  ? 192 GLN A C   1 
ATOM   4684 O O   . GLN C 1 196 ? 37.42870  70.30492 11.72639  1.000 33.97739  ? 192 GLN A O   1 
ATOM   4685 C CB  . GLN C 1 196 ? 35.79102  72.45258 10.27809  1.000 41.56370  ? 192 GLN A CB  1 
ATOM   4686 C CG  . GLN C 1 196 ? 34.43632  72.33729 10.96509  1.000 40.19149  ? 192 GLN A CG  1 
ATOM   4687 C CD  . GLN C 1 196 ? 34.17367  73.49827 11.90395  1.000 51.53529  ? 192 GLN A CD  1 
ATOM   4688 O OE1 . GLN C 1 196 ? 34.02600  73.31115 13.11726  1.000 43.70959  ? 192 GLN A OE1 1 
ATOM   4689 N NE2 . GLN C 1 196 ? 34.13105  74.71065 11.34985  1.000 47.10122  ? 192 GLN A NE2 1 
ATOM   4690 N N   . THR C 1 197 ? 36.74077  71.60211 13.44464  1.000 37.80218  ? 193 THR A N   1 
ATOM   4691 C CA  . THR C 1 197 ? 36.66030  70.50055 14.40255  1.000 30.60328  ? 193 THR A CA  1 
ATOM   4692 C C   . THR C 1 197 ? 35.29672  69.81990 14.30015  1.000 25.70808  ? 193 THR A C   1 
ATOM   4693 O O   . THR C 1 197 ? 34.26144  70.49210 14.23913  1.000 26.69441  ? 193 THR A O   1 
ATOM   4694 C CB  . THR C 1 197 ? 36.88710  71.01357 15.82634  1.000 33.01475  ? 193 THR A CB  1 
ATOM   4695 O OG1 . THR C 1 197 ? 38.17879  71.62390 15.91428  1.000 34.32511  ? 193 THR A OG1 1 
ATOM   4696 C CG2 . THR C 1 197 ? 36.80678  69.86873 16.84354  1.000 31.62179  ? 193 THR A CG2 1 
ATOM   4697 N N   . TYR C 1 198 ? 35.29860  68.48796 14.26299  1.000 22.72336  ? 194 TYR A N   1 
ATOM   4698 C CA  . TYR C 1 198 ? 34.07741  67.68710 14.23196  1.000 21.39313  ? 194 TYR A CA  1 
ATOM   4699 C C   . TYR C 1 198 ? 34.03117  66.82060 15.48609  1.000 25.63721  ? 194 TYR A C   1 
ATOM   4700 O O   . TYR C 1 198 ? 34.93439  66.00879 15.71589  1.000 23.91359  ? 194 TYR A O   1 
ATOM   4701 C CB  . TYR C 1 198 ? 34.01361  66.82465 12.96670  1.000 23.97202  ? 194 TYR A CB  1 
ATOM   4702 C CG  . TYR C 1 198 ? 33.96200  67.66326 11.70251  1.000 23.52976  ? 194 TYR A CG  1 
ATOM   4703 C CD1 . TYR C 1 198 ? 32.78767  68.30473 11.32473  1.000 26.11184  ? 194 TYR A CD1 1 
ATOM   4704 C CD2 . TYR C 1 198 ? 35.08661  67.83335 10.91149  1.000 26.82663  ? 194 TYR A CD2 1 
ATOM   4705 C CE1 . TYR C 1 198 ? 32.73433  69.08910 10.17970  1.000 30.45742  ? 194 TYR A CE1 1 
ATOM   4706 C CE2 . TYR C 1 198 ? 35.04563  68.61915 9.76500   1.000 28.53118  ? 194 TYR A CE2 1 
ATOM   4707 C CZ  . TYR C 1 198 ? 33.86954  69.24238 9.40642   1.000 31.66000  ? 194 TYR A CZ  1 
ATOM   4708 O OH  . TYR C 1 198 ? 33.81687  70.02308 8.26943   1.000 34.27609  ? 194 TYR A OH  1 
ATOM   4709 N N   . ILE C 1 199 ? 32.99787  67.01667 16.29895  1.000 19.76394  ? 195 ILE A N   1 
ATOM   4710 C CA  . ILE C 1 199 ? 32.77936  66.25631 17.52804  1.000 25.68940  ? 195 ILE A CA  1 
ATOM   4711 C C   . ILE C 1 199 ? 31.38453  65.66271 17.46993  1.000 20.31982  ? 195 ILE A C   1 
ATOM   4712 O O   . ILE C 1 199 ? 30.41073  66.39788 17.27837  1.000 26.19468  ? 195 ILE A O   1 
ATOM   4713 C CB  . ILE C 1 199 ? 32.92070  67.13736 18.78312  1.000 28.33997  ? 195 ILE A CB  1 
ATOM   4714 C CG1 . ILE C 1 199 ? 34.32919  67.73382 18.85978  1.000 30.60131  ? 195 ILE A CG1 1 
ATOM   4715 C CG2 . ILE C 1 199 ? 32.56184  66.33333 20.05730  1.000 23.30741  ? 195 ILE A CG2 1 
ATOM   4716 C CD1 . ILE C 1 199 ? 34.45702  68.87094 19.85414  1.000 30.35070  ? 195 ILE A CD1 1 
ATOM   4717 N N   . CYS C 1 200 ? 31.27372  64.34266 17.63838  1.000 20.70841  ? 196 CYS A N   1 
ATOM   4718 C CA  . CYS C 1 200 ? 29.94446  63.77691 17.78490  1.000 25.12792  ? 196 CYS A CA  1 
ATOM   4719 C C   . CYS C 1 200 ? 29.57526  63.67307 19.26084  1.000 25.75742  ? 196 CYS A C   1 
ATOM   4720 O O   . CYS C 1 200 ? 30.39526  63.29410 20.09923  1.000 22.91962  ? 196 CYS A O   1 
ATOM   4721 C CB  . CYS C 1 200 ? 29.81870  62.42242 17.08208  1.000 22.09018  ? 196 CYS A CB  1 
ATOM   4722 S SG  . CYS C 1 200 ? 30.54439  60.98154 17.86190  1.000 30.76242  ? 196 CYS A SG  1 
ATOM   4723 N N   . ASN C 1 201 ? 28.33319  64.04302 19.56628  1.000 21.49688  ? 197 ASN A N   1 
ATOM   4724 C CA  . ASN C 1 201 ? 27.79438  64.07882 20.92426  1.000 24.42163  ? 197 ASN A CA  1 
ATOM   4725 C C   . ASN C 1 201 ? 26.75307  62.97217 21.04107  1.000 23.69132  ? 197 ASN A C   1 
ATOM   4726 O O   . ASN C 1 201 ? 25.68369  63.05160 20.42407  1.000 24.65149  ? 197 ASN A O   1 
ATOM   4727 C CB  . ASN C 1 201 ? 27.15443  65.43218 21.23882  1.000 24.11850  ? 197 ASN A CB  1 
ATOM   4728 C CG  . ASN C 1 201 ? 27.93066  66.60375 20.67646  1.000 28.41867  ? 197 ASN A CG  1 
ATOM   4729 O OD1 . ASN C 1 201 ? 27.47002  67.27659 19.75284  1.000 27.67277  ? 197 ASN A OD1 1 
ATOM   4730 N ND2 . ASN C 1 201 ? 29.09294  66.88043 21.25362  1.000 21.97050  ? 197 ASN A ND2 1 
ATOM   4731 N N   . VAL C 1 202 ? 27.04064  61.96081 21.85155  1.000 20.87626  ? 198 VAL A N   1 
ATOM   4732 C CA  . VAL C 1 202 ? 26.19351  60.77597 21.95732  1.000 18.41427  ? 198 VAL A CA  1 
ATOM   4733 C C   . VAL C 1 202 ? 25.58299  60.73433 23.35242  1.000 23.74627  ? 198 VAL A C   1 
ATOM   4734 O O   . VAL C 1 202 ? 26.30269  60.65590 24.35473  1.000 20.13073  ? 198 VAL A O   1 
ATOM   4735 C CB  . VAL C 1 202 ? 26.99792  59.50477 21.65743  1.000 20.00534  ? 198 VAL A CB  1 
ATOM   4736 C CG1 . VAL C 1 202 ? 26.12453  58.25441 21.77472  1.000 18.68013  ? 198 VAL A CG1 1 
ATOM   4737 C CG2 . VAL C 1 202 ? 27.61615  59.60727 20.26521  1.000 19.13030  ? 198 VAL A CG2 1 
ATOM   4738 N N   . ASN C 1 203 ? 24.26107  60.77930 23.42859  1.000 20.71919  ? 199 ASN A N   1 
ATOM   4739 C CA  . ASN C 1 203 ? 23.58138  60.75160 24.71168  1.000 25.08617  ? 199 ASN A CA  1 
ATOM   4740 C C   . ASN C 1 203 ? 22.86715  59.41916 24.87506  1.000 24.03359  ? 199 ASN A C   1 
ATOM   4741 O O   . ASN C 1 203 ? 22.14571  58.98240 23.97658  1.000 20.24006  ? 199 ASN A O   1 
ATOM   4742 C CB  . ASN C 1 203 ? 22.58965  61.91031 24.84703  1.000 23.90299  ? 199 ASN A CB  1 
ATOM   4743 C CG  . ASN C 1 203 ? 22.30040  62.24288 26.31453  1.000 42.28078  ? 199 ASN A CG  1 
ATOM   4744 O OD1 . ASN C 1 203 ? 23.16293  62.76567 27.01823  1.000 36.26106  ? 199 ASN A OD1 1 
ATOM   4745 N ND2 . ASN C 1 203 ? 21.09752  61.92635 26.77677  1.000 39.72815  ? 199 ASN A ND2 1 
ATOM   4746 N N   . HIS C 1 204 ? 23.06690  58.77373 26.01785  1.000 24.03895  ? 200 HIS A N   1 
ATOM   4747 C CA  . HIS C 1 204 ? 22.42113  57.49157 26.31423  1.000 20.30459  ? 200 HIS A CA  1 
ATOM   4748 C C   . HIS C 1 204 ? 21.78990  57.62855 27.69687  1.000 22.84289  ? 200 HIS A C   1 
ATOM   4749 O O   . HIS C 1 204 ? 22.39532  57.29203 28.70914  1.000 19.97308  ? 200 HIS A O   1 
ATOM   4750 C CB  . HIS C 1 204 ? 23.43178  56.33434 26.21912  1.000 18.99110  ? 200 HIS A CB  1 
ATOM   4751 C CG  . HIS C 1 204 ? 22.82115  54.97874 26.37371  1.000 24.09753  ? 200 HIS A CG  1 
ATOM   4752 N ND1 . HIS C 1 204 ? 23.21758  54.09032 27.35344  1.000 23.82978  ? 200 HIS A ND1 1 
ATOM   4753 C CD2 . HIS C 1 204 ? 21.83729  54.35793 25.67525  1.000 19.76791  ? 200 HIS A CD2 1 
ATOM   4754 C CE1 . HIS C 1 204 ? 22.50435  52.98000 27.25213  1.000 23.17549  ? 200 HIS A CE1 1 
ATOM   4755 N NE2 . HIS C 1 204 ? 21.66728  53.11362 26.23675  1.000 21.76669  ? 200 HIS A NE2 1 
ATOM   4756 N N   . LYS C 1 205 ? 20.57815  58.17764 27.72651  1.000 21.90781  ? 201 LYS A N   1 
ATOM   4757 C CA  . LYS C 1 205 ? 19.86683  58.36847 28.98911  1.000 24.53318  ? 201 LYS A CA  1 
ATOM   4758 C C   . LYS C 1 205 ? 19.68035  57.08904 29.80243  1.000 26.99238  ? 201 LYS A C   1 
ATOM   4759 O O   . LYS C 1 205 ? 19.78941  57.16773 31.04232  1.000 25.69696  ? 201 LYS A O   1 
ATOM   4760 C CB  . LYS C 1 205 ? 18.51679  59.04749 28.71629  1.000 27.36952  ? 201 LYS A CB  1 
ATOM   4761 C CG  . LYS C 1 205 ? 17.59201  59.12826 29.93454  1.000 38.15960  ? 201 LYS A CG  1 
ATOM   4762 C CD  . LYS C 1 205 ? 18.18318  59.94205 31.09974  1.000 45.62110  ? 201 LYS A CD  1 
ATOM   4763 C CE  . LYS C 1 205 ? 17.98354  61.44889 30.91289  1.000 58.49509  ? 201 LYS A CE  1 
ATOM   4764 N NZ  . LYS C 1 205 ? 18.36066  62.25444 32.12585  1.000 49.05421  ? 201 LYS A NZ  1 
ATOM   4765 N N   . PRO C 1 206 ? 19.43253  55.90891 29.21210  1.000 23.93531  ? 202 PRO A N   1 
ATOM   4766 C CA  . PRO C 1 206 ? 19.27419  54.70841 30.05194  1.000 27.15055  ? 202 PRO A CA  1 
ATOM   4767 C C   . PRO C 1 206 ? 20.46823  54.36897 30.93245  1.000 25.61738  ? 202 PRO A C   1 
ATOM   4768 O O   . PRO C 1 206 ? 20.25879  53.78089 31.99658  1.000 23.64522  ? 202 PRO A O   1 
ATOM   4769 C CB  . PRO C 1 206 ? 19.01336  53.59415 29.02987  1.000 24.70102  ? 202 PRO A CB  1 
ATOM   4770 C CG  . PRO C 1 206 ? 18.39298  54.28737 27.87574  1.000 22.84637  ? 202 PRO A CG  1 
ATOM   4771 C CD  . PRO C 1 206 ? 19.09964  55.61660 27.79635  1.000 25.21139  ? 202 PRO A CD  1 
ATOM   4772 N N   . SER C 1 207 ? 21.70764  54.65038 30.52228  1.000 21.93762  ? 203 SER A N   1 
ATOM   4773 C CA  . SER C 1 207 ? 22.85453  54.42688 31.39808  1.000 23.28888  ? 203 SER A CA  1 
ATOM   4774 C C   . SER C 1 207 ? 23.38332  55.72830 31.98624  1.000 22.90804  ? 203 SER A C   1 
ATOM   4775 O O   . SER C 1 207 ? 24.45847  55.73452 32.59507  1.000 23.84140  ? 203 SER A O   1 
ATOM   4776 C CB  . SER C 1 207 ? 23.98148  53.70166 30.66131  1.000 21.07518  ? 203 SER A CB  1 
ATOM   4777 O OG  . SER C 1 207 ? 24.57948  54.55477 29.70148  1.000 23.23769  ? 203 SER A OG  1 
ATOM   4778 N N   . ASN C 1 208 ? 22.65731  56.82311 31.80284  1.000 18.27200  ? 204 ASN A N   1 
ATOM   4779 C CA  . ASN C 1 208 ? 23.07935  58.14372 32.28439  1.000 22.99846  ? 204 ASN A CA  1 
ATOM   4780 C C   . ASN C 1 208 ? 24.46831  58.50799 31.77234  1.000 23.69558  ? 204 ASN A C   1 
ATOM   4781 O O   . ASN C 1 208 ? 25.28162  59.07648 32.49824  1.000 23.25749  ? 204 ASN A O   1 
ATOM   4782 C CB  . ASN C 1 208 ? 23.02994  58.21111 33.81405  1.000 25.85336  ? 204 ASN A CB  1 
ATOM   4783 C CG  . ASN C 1 208 ? 21.63069  58.03737 34.34933  1.000 34.62222  ? 204 ASN A CG  1 
ATOM   4784 O OD1 . ASN C 1 208 ? 20.77232  58.90217 34.15845  1.000 38.27244  ? 204 ASN A OD1 1 
ATOM   4785 N ND2 . ASN C 1 208 ? 21.38816  56.91707 35.03181  1.000 36.71563  ? 204 ASN A ND2 1 
ATOM   4786 N N   . THR C 1 209 ? 24.74925  58.16873 30.51005  1.000 23.28897  ? 205 THR A N   1 
ATOM   4787 C CA  . THR C 1 209 ? 26.06099  58.37151 29.91323  1.000 22.16048  ? 205 THR A CA  1 
ATOM   4788 C C   . THR C 1 209 ? 25.94114  59.34576 28.75422  1.000 22.81481  ? 205 THR A C   1 
ATOM   4789 O O   . THR C 1 209 ? 24.99138  59.28284 27.97551  1.000 23.99999  ? 205 THR A O   1 
ATOM   4790 C CB  . THR C 1 209 ? 26.66620  57.04997 29.40109  1.000 26.85990  ? 205 THR A CB  1 
ATOM   4791 O OG1 . THR C 1 209 ? 26.55430  56.03795 30.41378  1.000 29.29338  ? 205 THR A OG1 1 
ATOM   4792 C CG2 . THR C 1 209 ? 28.13238  57.22720 29.04607  1.000 24.65067  ? 205 THR A CG2 1 
ATOM   4793 N N   . LYS C 1 210 ? 26.88780  60.26383 28.66790  1.000 24.01946  ? 206 LYS A N   1 
ATOM   4794 C CA  . LYS C 1 210 ? 27.08244  61.10133 27.49600  1.000 20.90663  ? 206 LYS A CA  1 
ATOM   4795 C C   . LYS C 1 210 ? 28.52600  60.93091 27.05754  1.000 24.91454  ? 206 LYS A C   1 
ATOM   4796 O O   . LYS C 1 210 ? 29.43461  60.90172 27.89644  1.000 20.36596  ? 206 LYS A O   1 
ATOM   4797 C CB  . LYS C 1 210 ? 26.76277  62.57561 27.80771  1.000 18.21104  ? 206 LYS A CB  1 
ATOM   4798 C CG  . LYS C 1 210 ? 27.01020  63.56494 26.67037  1.000 39.18161  ? 206 LYS A CG  1 
ATOM   4799 C CD  . LYS C 1 210 ? 26.57882  64.97043 27.09689  1.000 39.37666  ? 206 LYS A CD  1 
ATOM   4800 C CE  . LYS C 1 210 ? 27.61397  66.03400 26.73533  1.000 55.30074  ? 206 LYS A CE  1 
ATOM   4801 N NZ  . LYS C 1 210 ? 28.89035  65.90235 27.49375  1.000 45.90018  ? 206 LYS A NZ  1 
ATOM   4802 N N   . VAL C 1 211 ? 28.73089  60.77019 25.75034  1.000 19.91902  ? 207 VAL A N   1 
ATOM   4803 C CA  . VAL C 1 211 ? 30.05761  60.58348 25.18122  1.000 18.75283  ? 207 VAL A CA  1 
ATOM   4804 C C   . VAL C 1 211 ? 30.25749  61.63873 24.10609  1.000 24.38435  ? 207 VAL A C   1 
ATOM   4805 O O   . VAL C 1 211 ? 29.37880  61.83557 23.25952  1.000 26.87565  ? 207 VAL A O   1 
ATOM   4806 C CB  . VAL C 1 211 ? 30.24424  59.16777 24.60136  1.000 18.20413  ? 207 VAL A CB  1 
ATOM   4807 C CG1 . VAL C 1 211 ? 31.67969  58.99305 24.07678  1.000 20.90215  ? 207 VAL A CG1 1 
ATOM   4808 C CG2 . VAL C 1 211 ? 29.94347  58.11684 25.65967  1.000 16.28680  ? 207 VAL A CG2 1 
ATOM   4809 N N   . ASP C 1 212 ? 31.37846  62.35229 24.16884  1.000 23.75522  ? 208 ASP A N   1 
ATOM   4810 C CA  . ASP C 1 212 ? 31.76902  63.30303 23.12911  1.000 25.99769  ? 208 ASP A CA  1 
ATOM   4811 C C   . ASP C 1 212 ? 33.06958  62.81141 22.51563  1.000 31.71517  ? 208 ASP A C   1 
ATOM   4812 O O   . ASP C 1 212 ? 34.04623  62.56532 23.23664  1.000 26.08023  ? 208 ASP A O   1 
ATOM   4813 C CB  . ASP C 1 212 ? 31.95817  64.72359 23.68431  1.000 24.33485  ? 208 ASP A CB  1 
ATOM   4814 C CG  . ASP C 1 212 ? 30.67976  65.30912 24.26263  1.000 35.52278  ? 208 ASP A CG  1 
ATOM   4815 O OD1 . ASP C 1 212 ? 29.69305  65.50546 23.51554  1.000 33.93963  ? 208 ASP A OD1 1 
ATOM   4816 O OD2 . ASP C 1 212 ? 30.65335  65.57447 25.48430  1.000 44.24999  ? 208 ASP A OD2 1 
ATOM   4817 N N   . LYS C 1 213 ? 33.08379  62.65625 21.19278  1.000 21.51580  ? 209 LYS A N   1 
ATOM   4818 C CA  . LYS C 1 213 ? 34.22736  62.07712 20.50666  1.000 19.37554  ? 209 LYS A CA  1 
ATOM   4819 C C   . LYS C 1 213 ? 34.65389  63.01623 19.39130  1.000 27.66483  ? 209 LYS A C   1 
ATOM   4820 O O   . LYS C 1 213 ? 33.85653  63.30233 18.49229  1.000 18.86641  ? 209 LYS A O   1 
ATOM   4821 C CB  . LYS C 1 213 ? 33.87283  60.70411 19.93214  1.000 20.01888  ? 209 LYS A CB  1 
ATOM   4822 C CG  . LYS C 1 213 ? 35.01993  60.05293 19.21960  1.000 25.85991  ? 209 LYS A CG  1 
ATOM   4823 C CD  . LYS C 1 213 ? 36.12028  59.76882 20.20880  1.000 27.40965  ? 209 LYS A CD  1 
ATOM   4824 C CE  . LYS C 1 213 ? 37.16781  58.88536 19.58577  1.000 29.85492  ? 209 LYS A CE  1 
ATOM   4825 N NZ  . LYS C 1 213 ? 38.29458  58.62237 20.52715  1.000 34.61632  ? 209 LYS A NZ  1 
ATOM   4826 N N   . LYS C 1 214 ? 35.89546  63.49489 19.45000  1.000 23.31787  ? 210 LYS A N   1 
ATOM   4827 C CA  . LYS C 1 214 ? 36.43468  64.32259 18.37763  1.000 24.94844  ? 210 LYS A CA  1 
ATOM   4828 C C   . LYS C 1 214 ? 36.98416  63.40488 17.29985  1.000 22.50689  ? 210 LYS A C   1 
ATOM   4829 O O   . LYS C 1 214 ? 37.81961  62.54403 17.57380  1.000 23.31125  ? 210 LYS A O   1 
ATOM   4830 C CB  . LYS C 1 214 ? 37.52988  65.26031 18.88450  1.000 31.91407  ? 210 LYS A CB  1 
ATOM   4831 C CG  . LYS C 1 214 ? 38.20245  66.07665 17.76765  1.000 33.02004  ? 210 LYS A CG  1 
ATOM   4832 C CD  . LYS C 1 214 ? 39.47507  66.76257 18.23078  1.000 32.21363  ? 210 LYS A CD  1 
ATOM   4833 C CE  . LYS C 1 214 ? 39.20016  67.69898 19.39066  1.000 46.96111  ? 210 LYS A CE  1 
ATOM   4834 N NZ  . LYS C 1 214 ? 40.43966  68.00904 20.17362  1.000 51.98095  ? 210 LYS A NZ  1 
ATOM   4835 N N   . VAL C 1 215 ? 36.50593  63.57506 16.08324  1.000 24.53889  ? 211 VAL A N   1 
ATOM   4836 C CA  . VAL C 1 215 ? 36.86625  62.70699 14.97535  1.000 21.19696  ? 211 VAL A CA  1 
ATOM   4837 C C   . VAL C 1 215 ? 37.92503  63.44609 14.16360  1.000 31.61719  ? 211 VAL A C   1 
ATOM   4838 O O   . VAL C 1 215 ? 37.64550  64.49350 13.56941  1.000 22.39850  ? 211 VAL A O   1 
ATOM   4839 C CB  . VAL C 1 215 ? 35.62843  62.34633 14.14649  1.000 23.41644  ? 211 VAL A CB  1 
ATOM   4840 C CG1 . VAL C 1 215 ? 35.98838  61.45848 12.95706  1.000 19.01223  ? 211 VAL A CG1 1 
ATOM   4841 C CG2 . VAL C 1 215 ? 34.57873  61.66673 15.05192  1.000 21.24837  ? 211 VAL A CG2 1 
ATOM   4842 N N   . GLU C 1 216 ? 39.15862  62.92914 14.17449  1.000 26.83561  ? 212 GLU A N   1 
ATOM   4843 C CA  . GLU C 1 216 ? 40.27087  63.58963 13.50209  1.000 34.17346  ? 212 GLU A CA  1 
ATOM   4844 C C   . GLU C 1 216 ? 40.66506  62.84689 12.22277  1.000 32.34510  ? 212 GLU A C   1 
ATOM   4845 O O   . GLU C 1 216 ? 40.52698  61.62321 12.13929  1.000 29.28431  ? 212 GLU A O   1 
ATOM   4846 C CB  . GLU C 1 216 ? 41.48978  63.69365 14.43236  1.000 31.70469  ? 212 GLU A CB  1 
ATOM   4847 C CG  . GLU C 1 216 ? 41.28223  64.66167 15.61101  1.000 41.12215  ? 212 GLU A CG  1 
ATOM   4848 C CD  . GLU C 1 216 ? 42.41532  64.63180 16.64637  1.000 60.11395  ? 212 GLU A CD  1 
ATOM   4849 O OE1 . GLU C 1 216 ? 43.06572  63.57552 16.81274  1.000 56.71190  ? 212 GLU A OE1 1 
ATOM   4850 O OE2 . GLU C 1 216 ? 42.65344  65.67291 17.30038  1.000 63.38237  ? 212 GLU A OE2 1 
ATOM   4851 N N   . PRO C 1 217 ? 41.16640  63.56171 11.21448  1.000 36.94916  ? 213 PRO A N   1 
ATOM   4852 C CA  . PRO C 1 217 ? 41.61274  62.90055 9.98158   1.000 38.89993  ? 213 PRO A CA  1 
ATOM   4853 C C   . PRO C 1 217 ? 42.66198  61.83078 10.25294  1.000 43.67333  ? 213 PRO A C   1 
ATOM   4854 O O   . PRO C 1 217 ? 43.33160  61.82704 11.28989  1.000 41.30244  ? 213 PRO A O   1 
ATOM   4855 C CB  . PRO C 1 217 ? 42.20359  64.04935 9.15337   1.000 41.30716  ? 213 PRO A CB  1 
ATOM   4856 C CG  . PRO C 1 217 ? 41.57913  65.28037 9.69693   1.000 42.01939  ? 213 PRO A CG  1 
ATOM   4857 C CD  . PRO C 1 217 ? 41.33831  65.02361 11.15766  1.000 39.20933  ? 213 PRO A CD  1 
ATOM   4858 N N   . LYS C 1 218 ? 42.80526  60.93275 9.27528   1.000 48.17208  ? 214 LYS A N   1 
ATOM   4859 C CA  . LYS C 1 218 ? 43.66031  59.73532 9.33491   1.000 59.54363  ? 214 LYS A CA  1 
ATOM   4860 C C   . LYS C 1 218 ? 43.08673  58.69379 10.28382  1.000 51.26033  ? 214 LYS A C   1 
ATOM   4861 O O   . LYS C 1 218 ? 43.79749  57.78256 10.71331  1.000 59.64220  ? 214 LYS A O   1 
ATOM   4862 C CB  . LYS C 1 218 ? 45.09566  60.06492 9.75863   1.000 58.30557  ? 214 LYS A CB  1 
ATOM   4863 C CG  . LYS C 1 218 ? 46.00799  60.56101 8.66091   1.000 63.63860  ? 214 LYS A CG  1 
ATOM   4864 C CD  . LYS C 1 218 ? 47.37297  60.91318 9.25013   1.000 64.64516  ? 214 LYS A CD  1 
ATOM   4865 C CE  . LYS C 1 218 ? 48.38550  61.29623 8.18491   1.000 67.75526  ? 214 LYS A CE  1 
ATOM   4866 N NZ  . LYS C 1 218 ? 48.82583  60.10752 7.40591   1.000 67.78510  ? 214 LYS A NZ  1 
ATOM   4867 N N   . ASP D 2 1   ? -10.20349 38.79454 17.91325  1.000 69.92288  ? 1   ASP B N   1 
ATOM   4868 C CA  . ASP D 2 1   ? -10.30061 37.79691 16.84987  1.000 80.88989  ? 1   ASP B CA  1 
ATOM   4869 C C   . ASP D 2 1   ? -10.49105 38.45558 15.47598  1.000 79.34716  ? 1   ASP B C   1 
ATOM   4870 O O   . ASP D 2 1   ? -10.30639 37.82294 14.43366  1.000 79.11187  ? 1   ASP B O   1 
ATOM   4871 C CB  . ASP D 2 1   ? -11.44909 36.81635 17.13864  1.000 90.47709  ? 1   ASP B CB  1 
ATOM   4872 C CG  . ASP D 2 1   ? -12.82941 37.42939 16.90786  1.000 94.28293  ? 1   ASP B CG  1 
ATOM   4873 O OD1 . ASP D 2 1   ? -13.32106 37.39121 15.75740  1.000 96.84650  ? 1   ASP B OD1 1 
ATOM   4874 O OD2 . ASP D 2 1   ? -13.42827 37.94177 17.87824  1.000 93.68895  ? 1   ASP B OD2 1 
ATOM   4875 N N   . ILE D 2 2   ? -10.84831 39.74098 15.49008  1.000 74.23638  ? 2   ILE B N   1 
ATOM   4876 C CA  . ILE D 2 2   ? -11.15934 40.45573 14.25660  1.000 58.96503  ? 2   ILE B CA  1 
ATOM   4877 C C   . ILE D 2 2   ? -9.88067  40.72323 13.46087  1.000 61.89905  ? 2   ILE B C   1 
ATOM   4878 O O   . ILE D 2 2   ? -8.76494  40.72587 13.99234  1.000 65.19070  ? 2   ILE B O   1 
ATOM   4879 C CB  . ILE D 2 2   ? -11.90587 41.76199 14.58004  1.000 62.86597  ? 2   ILE B CB  1 
ATOM   4880 C CG1 . ILE D 2 2   ? -12.96544 41.52630 15.66298  1.000 70.02900  ? 2   ILE B CG1 1 
ATOM   4881 C CG2 . ILE D 2 2   ? -12.57586 42.32246 13.34682  1.000 63.62375  ? 2   ILE B CG2 1 
ATOM   4882 C CD1 . ILE D 2 2   ? -12.53973 41.94585 17.06462  1.000 66.61928  ? 2   ILE B CD1 1 
ATOM   4883 N N   . GLN D 2 3   ? -10.04798 40.94011 12.15601  1.000 51.50443  ? 3   GLN B N   1 
ATOM   4884 C CA  . GLN D 2 3   ? -8.93023  41.26175 11.28118  1.000 55.57905  ? 3   GLN B CA  1 
ATOM   4885 C C   . GLN D 2 3   ? -9.31715  42.36680 10.30920  1.000 52.10337  ? 3   GLN B C   1 
ATOM   4886 O O   . GLN D 2 3   ? -10.46006 42.44229 9.84941   1.000 51.24646  ? 3   GLN B O   1 
ATOM   4887 C CB  . GLN D 2 3   ? -8.46024  40.04636 10.48844  1.000 52.90485  ? 3   GLN B CB  1 
ATOM   4888 C CG  . GLN D 2 3   ? -7.80387  38.98644 11.32760  1.000 70.55108  ? 3   GLN B CG  1 
ATOM   4889 C CD  . GLN D 2 3   ? -7.09262  37.97461 10.46944  1.000 74.87374  ? 3   GLN B CD  1 
ATOM   4890 O OE1 . GLN D 2 3   ? -7.02403  38.12856 9.24818   1.000 73.93892  ? 3   GLN B OE1 1 
ATOM   4891 N NE2 . GLN D 2 3   ? -6.55332  36.93336 11.09623  1.000 75.65585  ? 3   GLN B NE2 1 
ATOM   4892 N N   . MET D 2 4   ? -8.34417  43.22468 10.00098  1.000 51.35565  ? 4   MET B N   1 
ATOM   4893 C CA  . MET D 2 4   ? -8.47333  44.23315 8.95466   1.000 43.86755  ? 4   MET B CA  1 
ATOM   4894 C C   . MET D 2 4   ? -7.30658  44.07184 7.99504   1.000 42.35541  ? 4   MET B C   1 
ATOM   4895 O O   . MET D 2 4   ? -6.14592  44.11132 8.41839   1.000 42.14450  ? 4   MET B O   1 
ATOM   4896 C CB  . MET D 2 4   ? -8.49395  45.64721 9.53496   1.000 41.99233  ? 4   MET B CB  1 
ATOM   4897 C CG  . MET D 2 4   ? -9.58935  45.88622 10.54436  1.000 44.80171  ? 4   MET B CG  1 
ATOM   4898 S SD  . MET D 2 4   ? -9.98517  47.63440 10.76624  1.000 60.91863  ? 4   MET B SD  1 
ATOM   4899 C CE  . MET D 2 4   ? -11.14233 47.92334 9.42954   1.000 43.39897  ? 4   MET B CE  1 
ATOM   4900 N N   . THR D 2 5   ? -7.61392  43.90811 6.71148   1.000 34.74737  ? 5   THR B N   1 
ATOM   4901 C CA  . THR D 2 5   ? -6.62535  43.62502 5.67444   1.000 46.88497  ? 5   THR B CA  1 
ATOM   4902 C C   . THR D 2 5   ? -6.47134  44.83507 4.76290   1.000 39.90279  ? 5   THR B C   1 
ATOM   4903 O O   . THR D 2 5   ? -7.42199  45.21501 4.07210   1.000 41.80120  ? 5   THR B O   1 
ATOM   4904 C CB  . THR D 2 5   ? -7.04192  42.40676 4.85214   1.000 49.08431  ? 5   THR B CB  1 
ATOM   4905 O OG1 . THR D 2 5   ? -7.51958  41.38561 5.73568   1.000 42.34024  ? 5   THR B OG1 1 
ATOM   4906 C CG2 . THR D 2 5   ? -5.86105  41.88274 4.03864   1.000 40.34008  ? 5   THR B CG2 1 
ATOM   4907 N N   . GLN D 2 6   ? -5.26759  45.40566 4.73513   1.000 35.16900  ? 6   GLN B N   1 
ATOM   4908 C CA  . GLN D 2 6   ? -4.96099  46.61557 3.97963   1.000 41.95762  ? 6   GLN B CA  1 
ATOM   4909 C C   . GLN D 2 6   ? -4.25984  46.27844 2.66925   1.000 39.89434  ? 6   GLN B C   1 
ATOM   4910 O O   . GLN D 2 6   ? -3.40821  45.38627 2.62719   1.000 44.86367  ? 6   GLN B O   1 
ATOM   4911 C CB  . GLN D 2 6   ? -4.06274  47.53865 4.80306   1.000 41.65561  ? 6   GLN B CB  1 
ATOM   4912 C CG  . GLN D 2 6   ? -4.61762  48.90905 5.05578   1.000 41.89624  ? 6   GLN B CG  1 
ATOM   4913 C CD  . GLN D 2 6   ? -3.69904  49.73443 5.92361   1.000 37.56555  ? 6   GLN B CD  1 
ATOM   4914 O OE1 . GLN D 2 6   ? -3.74075  49.64460 7.14811   1.000 32.93679  ? 6   GLN B OE1 1 
ATOM   4915 N NE2 . GLN D 2 6   ? -2.85608  50.53908 5.29294   1.000 34.23290  ? 6   GLN B NE2 1 
ATOM   4916 N N   . SER D 2 7   ? -4.59653  47.01811 1.60693   1.000 43.80015  ? 7   SER B N   1 
ATOM   4917 C CA  . SER D 2 7   ? -3.96467  46.83632 0.29793   1.000 47.09275  ? 7   SER B CA  1 
ATOM   4918 C C   . SER D 2 7   ? -3.67822  48.18301 -0.35193  1.000 45.13687  ? 7   SER B C   1 
ATOM   4919 O O   . SER D 2 7   ? -4.51110  49.09730 -0.26990  1.000 48.87375  ? 7   SER B O   1 
ATOM   4920 C CB  . SER D 2 7   ? -4.84667  46.00915 -0.64729  1.000 38.49938  ? 7   SER B CB  1 
ATOM   4921 O OG  . SER D 2 7   ? -5.40000  44.90022 0.03145   1.000 55.84056  ? 7   SER B OG  1 
ATOM   4922 N N   . PRO D 2 8   ? -2.50828  48.34245 -1.00002  1.000 43.36710  ? 8   PRO B N   1 
ATOM   4923 C CA  . PRO D 2 8   ? -1.40499  47.37382 -0.99571  1.000 38.69711  ? 8   PRO B CA  1 
ATOM   4924 C C   . PRO D 2 8   ? -0.58655  47.49399 0.28588   1.000 42.01175  ? 8   PRO B C   1 
ATOM   4925 O O   . PRO D 2 8   ? -0.91602  48.33190 1.12307   1.000 42.40303  ? 8   PRO B O   1 
ATOM   4926 C CB  . PRO D 2 8   ? -0.58084  47.78885 -2.20751  1.000 32.14304  ? 8   PRO B CB  1 
ATOM   4927 C CG  . PRO D 2 8   ? -0.75337  49.27967 -2.22476  1.000 32.30357  ? 8   PRO B CG  1 
ATOM   4928 C CD  . PRO D 2 8   ? -2.19635  49.50902 -1.84417  1.000 40.01558  ? 8   PRO B CD  1 
ATOM   4929 N N   . SER D 2 9   ? 0.46240   46.68305 0.43852   1.000 44.07535  ? 9   SER B N   1 
ATOM   4930 C CA  . SER D 2 9   ? 1.30775   46.78403 1.62582   1.000 48.36406  ? 9   SER B CA  1 
ATOM   4931 C C   . SER D 2 9   ? 2.30580   47.93198 1.51505   1.000 49.50132  ? 9   SER B C   1 
ATOM   4932 O O   . SER D 2 9   ? 2.70398   48.51044 2.53431   1.000 45.92806  ? 9   SER B O   1 
ATOM   4933 C CB  . SER D 2 9   ? 2.03992   45.46188 1.86708   1.000 46.03604  ? 9   SER B CB  1 
ATOM   4934 O OG  . SER D 2 9   ? 1.15020   44.47038 2.37064   1.000 46.58824  ? 9   SER B OG  1 
ATOM   4935 N N   . SER D 2 10  ? 2.70943   48.27749 0.29677   1.000 34.73743  ? 10  SER B N   1 
ATOM   4936 C CA  . SER D 2 10  ? 3.56973   49.42340 0.06278   1.000 41.60588  ? 10  SER B CA  1 
ATOM   4937 C C   . SER D 2 10  ? 3.26749   49.96131 -1.32050  1.000 42.16708  ? 10  SER B C   1 
ATOM   4938 O O   . SER D 2 10  ? 2.69355   49.26520 -2.16093  1.000 44.74917  ? 10  SER B O   1 
ATOM   4939 C CB  . SER D 2 10  ? 5.05522   49.06736 0.16606   1.000 39.98754  ? 10  SER B CB  1 
ATOM   4940 O OG  . SER D 2 10  ? 5.45875   48.32221 -0.96173  1.000 46.61540  ? 10  SER B OG  1 
ATOM   4941 N N   . LEU D 2 11  ? 3.66300   51.20987 -1.55322  1.000 40.23462  ? 11  LEU B N   1 
ATOM   4942 C CA  . LEU D 2 11  ? 3.48947   51.79029 -2.87600  1.000 42.34502  ? 11  LEU B CA  1 
ATOM   4943 C C   . LEU D 2 11  ? 4.41110   52.98648 -3.02295  1.000 46.42571  ? 11  LEU B C   1 
ATOM   4944 O O   . LEU D 2 11  ? 4.72142   53.67835 -2.04768  1.000 43.11089  ? 11  LEU B O   1 
ATOM   4945 C CB  . LEU D 2 11  ? 2.03244   52.19321 -3.14139  1.000 47.49154  ? 11  LEU B CB  1 
ATOM   4946 C CG  . LEU D 2 11  ? 1.35532   53.31326 -2.35577  1.000 42.15594  ? 11  LEU B CG  1 
ATOM   4947 C CD1 . LEU D 2 11  ? 1.54013   54.65841 -3.04505  1.000 39.30586  ? 11  LEU B CD1 1 
ATOM   4948 C CD2 . LEU D 2 11  ? -0.12163  52.98915 -2.21010  1.000 41.53721  ? 11  LEU B CD2 1 
ATOM   4949 N N   . SER D 2 12  ? 4.84928   53.20608 -4.25509  1.000 34.53249  ? 12  SER B N   1 
ATOM   4950 C CA  . SER D 2 12  ? 5.65156   54.35708 -4.62749  1.000 36.05427  ? 12  SER B CA  1 
ATOM   4951 C C   . SER D 2 12  ? 4.89630   55.15201 -5.68229  1.000 43.54225  ? 12  SER B C   1 
ATOM   4952 O O   . SER D 2 12  ? 4.24708   54.57364 -6.55597  1.000 43.64101  ? 12  SER B O   1 
ATOM   4953 C CB  . SER D 2 12  ? 7.01796   53.91967 -5.15666  1.000 38.87451  ? 12  SER B CB  1 
ATOM   4954 O OG  . SER D 2 12  ? 7.83475   55.04106 -5.42174  1.000 49.95632  ? 12  SER B OG  1 
ATOM   4955 N N   . ALA D 2 13  ? 4.96446   56.47574 -5.58833  1.000 37.12698  ? 13  ALA B N   1 
ATOM   4956 C CA  . ALA D 2 13  ? 4.20702   57.33799 -6.47987  1.000 37.92248  ? 13  ALA B CA  1 
ATOM   4957 C C   . ALA D 2 13  ? 4.91194   58.68212 -6.56747  1.000 43.43017  ? 13  ALA B C   1 
ATOM   4958 O O   . ALA D 2 13  ? 5.67959   59.05566 -5.67921  1.000 36.85876  ? 13  ALA B O   1 
ATOM   4959 C CB  . ALA D 2 13  ? 2.76138   57.50831 -5.99604  1.000 36.62968  ? 13  ALA B CB  1 
ATOM   4960 N N   . SER D 2 14  ? 4.65126   59.40458 -7.65229  1.000 40.77110  ? 14  SER B N   1 
ATOM   4961 C CA  . SER D 2 14  ? 5.24111   60.71984 -7.84573  1.000 38.04614  ? 14  SER B CA  1 
ATOM   4962 C C   . SER D 2 14  ? 4.34649   61.79124 -7.23589  1.000 31.31673  ? 14  SER B C   1 
ATOM   4963 O O   . SER D 2 14  ? 3.17681   61.55418 -6.92699  1.000 42.36119  ? 14  SER B O   1 
ATOM   4964 C CB  . SER D 2 14  ? 5.46561   60.99544 -9.33370  1.000 37.92030  ? 14  SER B CB  1 
ATOM   4965 O OG  . SER D 2 14  ? 6.27930   59.98961 -9.91597  1.000 51.01112  ? 14  SER B OG  1 
ATOM   4966 N N   . VAL D 2 15  ? 4.91072   62.98584 -7.06253  1.000 35.88344  ? 15  VAL B N   1 
ATOM   4967 C CA  . VAL D 2 15  ? 4.14930   64.08591 -6.47567  1.000 37.34229  ? 15  VAL B CA  1 
ATOM   4968 C C   . VAL D 2 15  ? 3.01713   64.47779 -7.41459  1.000 45.64121  ? 15  VAL B C   1 
ATOM   4969 O O   . VAL D 2 15  ? 3.21338   64.62505 -8.62803  1.000 45.77625  ? 15  VAL B O   1 
ATOM   4970 C CB  . VAL D 2 15  ? 5.06360   65.28303 -6.16703  1.000 49.82259  ? 15  VAL B CB  1 
ATOM   4971 C CG1 . VAL D 2 15  ? 4.23291   66.51846 -5.76833  1.000 35.92945  ? 15  VAL B CG1 1 
ATOM   4972 C CG2 . VAL D 2 15  ? 6.04618   64.92397 -5.06269  1.000 45.34571  ? 15  VAL B CG2 1 
ATOM   4973 N N   . GLY D 2 16  ? 1.82340   64.64996 -6.85544  1.000 48.31383  ? 16  GLY B N   1 
ATOM   4974 C CA  . GLY D 2 16  ? 0.64450   64.96859 -7.62600  1.000 41.54557  ? 16  GLY B CA  1 
ATOM   4975 C C   . GLY D 2 16  ? -0.20537  63.77419 -7.98721  1.000 48.65187  ? 16  GLY B C   1 
ATOM   4976 O O   . GLY D 2 16  ? -1.35592  63.96002 -8.40756  1.000 46.72875  ? 16  GLY B O   1 
ATOM   4977 N N   . ASP D 2 17  ? 0.32397   62.56010 -7.83925  1.000 44.15450  ? 17  ASP B N   1 
ATOM   4978 C CA  . ASP D 2 17  ? -0.44560  61.36829 -8.15764  1.000 42.19630  ? 17  ASP B CA  1 
ATOM   4979 C C   . ASP D 2 17  ? -1.61360  61.21522 -7.19297  1.000 45.79298  ? 17  ASP B C   1 
ATOM   4980 O O   . ASP D 2 17  ? -1.58598  61.70372 -6.05955  1.000 45.25824  ? 17  ASP B O   1 
ATOM   4981 C CB  . ASP D 2 17  ? 0.43519   60.11512 -8.11173  1.000 42.59011  ? 17  ASP B CB  1 
ATOM   4982 C CG  . ASP D 2 17  ? 1.36308   59.99867 -9.31393  1.000 44.07536  ? 17  ASP B CG  1 
ATOM   4983 O OD1 . ASP D 2 17  ? 1.40171   60.93075 -10.14813 1.000 44.18749  ? 17  ASP B OD1 1 
ATOM   4984 O OD2 . ASP D 2 17  ? 2.05856   58.96582 -9.43041  1.000 44.63414  ? 17  ASP B OD2 1 
ATOM   4985 N N   . ARG D 2 18  ? -2.66112  60.55832 -7.67668  1.000 38.83100  ? 18  ARG B N   1 
ATOM   4986 C CA  . ARG D 2 18  ? -3.78933  60.15166 -6.85636  1.000 45.05582  ? 18  ARG B CA  1 
ATOM   4987 C C   . ARG D 2 18  ? -3.52650  58.74686 -6.33407  1.000 52.99551  ? 18  ARG B C   1 
ATOM   4988 O O   . ARG D 2 18  ? -3.23762  57.83473 -7.11315  1.000 44.41271  ? 18  ARG B O   1 
ATOM   4989 C CB  . ARG D 2 18  ? -5.08414  60.18965 -7.66515  1.000 51.42212  ? 18  ARG B CB  1 
ATOM   4990 C CG  . ARG D 2 18  ? -6.16147  59.25315 -7.16625  1.000 49.89415  ? 18  ARG B CG  1 
ATOM   4991 C CD  . ARG D 2 18  ? -7.43121  59.43202 -7.97071  1.000 53.17106  ? 18  ARG B CD  1 
ATOM   4992 N NE  . ARG D 2 18  ? -7.97110  60.77256 -7.78281  1.000 65.44765  ? 18  ARG B NE  1 
ATOM   4993 C CZ  . ARG D 2 18  ? -9.02816  61.05794 -7.03363  1.000 70.26242  ? 18  ARG B CZ  1 
ATOM   4994 N NH1 . ARG D 2 18  ? -9.73841  60.10713 -6.44664  1.000 62.23478  ? 18  ARG B NH1 1 
ATOM   4995 N NH2 . ARG D 2 18  ? -9.38252  62.32931 -6.86955  1.000 63.04780  ? 18  ARG B NH2 1 
ATOM   4996 N N   . VAL D 2 19  ? -3.60855  58.58066 -5.01820  1.000 49.71883  ? 19  VAL B N   1 
ATOM   4997 C CA  . VAL D 2 19  ? -3.25988  57.33047 -4.35810  1.000 47.45873  ? 19  VAL B CA  1 
ATOM   4998 C C   . VAL D 2 19  ? -4.47453  56.81979 -3.59727  1.000 50.85358  ? 19  VAL B C   1 
ATOM   4999 O O   . VAL D 2 19  ? -5.19101  57.59520 -2.95403  1.000 47.14958  ? 19  VAL B O   1 
ATOM   5000 C CB  . VAL D 2 19  ? -2.04844  57.51053 -3.41844  1.000 52.48793  ? 19  VAL B CB  1 
ATOM   5001 C CG1 . VAL D 2 19  ? -1.93951  56.34763 -2.44561  1.000 45.13207  ? 19  VAL B CG1 1 
ATOM   5002 C CG2 . VAL D 2 19  ? -0.77189  57.63516 -4.24129  1.000 57.15381  ? 19  VAL B CG2 1 
ATOM   5003 N N   . THR D 2 20  ? -4.70609  55.51266 -3.68323  1.000 48.81945  ? 20  THR B N   1 
ATOM   5004 C CA  . THR D 2 20  ? -5.82235  54.84992 -3.02788  1.000 47.87386  ? 20  THR B CA  1 
ATOM   5005 C C   . THR D 2 20  ? -5.29462  53.72796 -2.14241  1.000 48.10032  ? 20  THR B C   1 
ATOM   5006 O O   . THR D 2 20  ? -4.47765  52.91809 -2.58902  1.000 44.82949  ? 20  THR B O   1 
ATOM   5007 C CB  . THR D 2 20  ? -6.79977  54.29905 -4.07150  1.000 48.54010  ? 20  THR B CB  1 
ATOM   5008 O OG1 . THR D 2 20  ? -7.68294  55.34391 -4.49567  1.000 52.34599  ? 20  THR B OG1 1 
ATOM   5009 C CG2 . THR D 2 20  ? -7.60721  53.15853 -3.50131  1.000 55.46411  ? 20  THR B CG2 1 
ATOM   5010 N N   . ILE D 2 21  ? -5.75210  53.68792 -0.88972  1.000 42.48322  ? 21  ILE B N   1 
ATOM   5011 C CA  . ILE D 2 21  ? -5.45415  52.60073 0.03765   1.000 39.05147  ? 21  ILE B CA  1 
ATOM   5012 C C   . ILE D 2 21  ? -6.77465  52.03392 0.53442   1.000 41.96721  ? 21  ILE B C   1 
ATOM   5013 O O   . ILE D 2 21  ? -7.67405  52.79086 0.91992   1.000 39.76118  ? 21  ILE B O   1 
ATOM   5014 C CB  . ILE D 2 21  ? -4.58605  53.06853 1.22037   1.000 47.81729  ? 21  ILE B CB  1 
ATOM   5015 C CG1 . ILE D 2 21  ? -3.30453  53.73036 0.72012   1.000 47.07000  ? 21  ILE B CG1 1 
ATOM   5016 C CG2 . ILE D 2 21  ? -4.23199  51.89188 2.12888   1.000 47.90051  ? 21  ILE B CG2 1 
ATOM   5017 C CD1 . ILE D 2 21  ? -2.53528  54.42732 1.81222   1.000 46.36506  ? 21  ILE B CD1 1 
ATOM   5018 N N   . THR D 2 22  ? -6.89158  50.70867 0.53112   1.000 47.40032  ? 22  THR B N   1 
ATOM   5019 C CA  . THR D 2 22  ? -8.12712  50.04882 0.92218   1.000 49.43686  ? 22  THR B CA  1 
ATOM   5020 C C   . THR D 2 22  ? -7.90494  49.16506 2.14219   1.000 46.00178  ? 22  THR B C   1 
ATOM   5021 O O   . THR D 2 22  ? -6.79763  48.69683 2.41648   1.000 39.99863  ? 22  THR B O   1 
ATOM   5022 C CB  . THR D 2 22  ? -8.71109  49.21378 -0.22604  1.000 43.96129  ? 22  THR B CB  1 
ATOM   5023 O OG1 . THR D 2 22  ? -7.83319  48.12253 -0.52825  1.000 44.42441  ? 22  THR B OG1 1 
ATOM   5024 C CG2 . THR D 2 22  ? -8.87500  50.07925 -1.45705  1.000 34.80588  ? 22  THR B CG2 1 
ATOM   5025 N N   . CYS D 2 23  ? -8.99272  48.94744 2.87506   1.000 43.55762  ? 23  CYS B N   1 
ATOM   5026 C CA  . CYS D 2 23  ? -8.96973  48.18019 4.11079   1.000 44.17992  ? 23  CYS B CA  1 
ATOM   5027 C C   . CYS D 2 23  ? -10.22349 47.31891 4.14644   1.000 46.15688  ? 23  CYS B C   1 
ATOM   5028 O O   . CYS D 2 23  ? -11.34051 47.84327 4.06475   1.000 43.52679  ? 23  CYS B O   1 
ATOM   5029 C CB  . CYS D 2 23  ? -8.90023  49.11969 5.31980   1.000 52.89886  ? 23  CYS B CB  1 
ATOM   5030 S SG  . CYS D 2 23  ? -8.79003  48.36012 6.94915   1.000 74.17555  ? 23  CYS B SG  1 
ATOM   5031 N N   . ARG D 2 24  ? -10.03792 46.00431 4.23972   1.000 53.02636  ? 24  ARG B N   1 
ATOM   5032 C CA  . ARG D 2 24  ? -11.13461 45.04509 4.26938   1.000 45.74487  ? 24  ARG B CA  1 
ATOM   5033 C C   . ARG D 2 24  ? -11.21405 44.43371 5.66030   1.000 44.44164  ? 24  ARG B C   1 
ATOM   5034 O O   . ARG D 2 24  ? -10.25157 43.81501 6.12512   1.000 40.77985  ? 24  ARG B O   1 
ATOM   5035 C CB  . ARG D 2 24  ? -10.94324 43.95802 3.21527   1.000 38.76389  ? 24  ARG B CB  1 
ATOM   5036 C CG  . ARG D 2 24  ? -12.05590 42.92871 3.19916   1.000 55.20559  ? 24  ARG B CG  1 
ATOM   5037 C CD  . ARG D 2 24  ? -12.64574 42.77547 1.80269   1.000 71.05888  ? 24  ARG B CD  1 
ATOM   5038 N NE  . ARG D 2 24  ? -11.68763 42.24028 0.84005   1.000 80.56357  ? 24  ARG B NE  1 
ATOM   5039 C CZ  . ARG D 2 24  ? -11.96492 41.99698 -0.43474  1.000 75.61301  ? 24  ARG B CZ  1 
ATOM   5040 N NH1 . ARG D 2 24  ? -13.16145 42.24694 -0.94090  1.000 71.18086  ? 24  ARG B NH1 1 
ATOM   5041 N NH2 . ARG D 2 24  ? -11.01904 41.48727 -1.22029  1.000 67.23264  ? 24  ARG B NH2 1 
ATOM   5042 N N   . ALA D 2 25  ? -12.35202 44.60989 6.31821   1.000 34.79772  ? 25  ALA B N   1 
ATOM   5043 C CA  . ALA D 2 25  ? -12.54773 44.06912 7.65331   1.000 44.00900  ? 25  ALA B CA  1 
ATOM   5044 C C   . ALA D 2 25  ? -13.18649 42.68529 7.57963   1.000 46.17870  ? 25  ALA B C   1 
ATOM   5045 O O   . ALA D 2 25  ? -13.75242 42.28531 6.56015   1.000 40.51889  ? 25  ALA B O   1 
ATOM   5046 C CB  . ALA D 2 25  ? -13.41034 45.00820 8.49522   1.000 45.62436  ? 25  ALA B CB  1 
ATOM   5047 N N   . SER D 2 26  ? -13.07748 41.94477 8.67801   1.000 38.54832  ? 26  SER B N   1 
ATOM   5048 C CA  . SER D 2 26  ? -13.66275 40.61276 8.73531   1.000 43.98749  ? 26  SER B CA  1 
ATOM   5049 C C   . SER D 2 26  ? -15.08059 40.62105 9.29006   1.000 44.96238  ? 26  SER B C   1 
ATOM   5050 O O   . SER D 2 26  ? -15.75166 39.58630 9.24273   1.000 46.51310  ? 26  SER B O   1 
ATOM   5051 C CB  . SER D 2 26  ? -12.77591 39.67564 9.56779   1.000 41.76729  ? 26  SER B CB  1 
ATOM   5052 O OG  . SER D 2 26  ? -12.69108 40.09164 10.92296  1.000 45.75683  ? 26  SER B OG  1 
ATOM   5053 N N   . GLN D 2 27  ? -15.54399 41.76315 9.79798   1.000 49.51769  ? 27  GLN B N   1 
ATOM   5054 C CA  . GLN D 2 27  ? -16.87171 41.92438 10.37700  1.000 50.66526  ? 27  GLN B CA  1 
ATOM   5055 C C   . GLN D 2 27  ? -17.28970 43.37785 10.23740  1.000 50.97616  ? 27  GLN B C   1 
ATOM   5056 O O   . GLN D 2 27  ? -16.45602 44.26802 10.04660  1.000 50.16395  ? 27  GLN B O   1 
ATOM   5057 C CB  . GLN D 2 27  ? -16.91535 41.53986 11.86275  1.000 47.66572  ? 27  GLN B CB  1 
ATOM   5058 C CG  . GLN D 2 27  ? -16.86431 40.05673 12.13105  1.000 59.93264  ? 27  GLN B CG  1 
ATOM   5059 C CD  . GLN D 2 27  ? -15.89712 39.71372 13.23433  1.000 60.50779  ? 27  GLN B CD  1 
ATOM   5060 O OE1 . GLN D 2 27  ? -15.93394 40.31236 14.31004  1.000 61.94470  ? 27  GLN B OE1 1 
ATOM   5061 N NE2 . GLN D 2 27  ? -15.00726 38.75723 12.96934  1.000 59.83412  ? 27  GLN B NE2 1 
ATOM   5062 N N   . SER D 2 28  A -18.59395 43.61021 10.35631  1.000 45.28528  ? 27  SER B N   1 
ATOM   5063 C CA  . SER D 2 28  A -19.10322 44.97212 10.43508  1.000 48.46423  ? 27  SER B CA  1 
ATOM   5064 C C   . SER D 2 28  A -18.43519 45.71514 11.58674  1.000 43.18414  ? 27  SER B C   1 
ATOM   5065 O O   . SER D 2 28  A -18.07709 45.12458 12.61005  1.000 42.67896  ? 27  SER B O   1 
ATOM   5066 C CB  . SER D 2 28  A -20.62103 44.95951 10.63823  1.000 48.83312  ? 27  SER B CB  1 
ATOM   5067 O OG  . SER D 2 28  A -21.19816 43.78612 10.09538  1.000 52.66466  ? 27  SER B OG  1 
ATOM   5068 N N   . VAL D 2 29  B -18.25539 47.01704 11.41324  1.000 34.08477  ? 27  VAL B N   1 
ATOM   5069 C CA  . VAL D 2 29  B -17.71336 47.84285 12.47898  1.000 36.43939  ? 27  VAL B CA  1 
ATOM   5070 C C   . VAL D 2 29  B -18.86794 48.46157 13.25570  1.000 42.34263  ? 27  VAL B C   1 
ATOM   5071 O O   . VAL D 2 29  B -19.98454 48.59532 12.75125  1.000 36.04535  ? 27  VAL B O   1 
ATOM   5072 C CB  . VAL D 2 29  B -16.76105 48.93357 11.94949  1.000 41.34937  ? 27  VAL B CB  1 
ATOM   5073 C CG1 . VAL D 2 29  B -15.62658 48.30952 11.14327  1.000 47.35736  ? 27  VAL B CG1 1 
ATOM   5074 C CG2 . VAL D 2 29  B -17.53225 49.95889 11.13373  1.000 37.17001  ? 27  VAL B CG2 1 
ATOM   5075 N N   . TRP D 2 30  ? -18.57859 48.84845 14.49980  1.000 42.06574  ? 28  TRP B N   1 
ATOM   5076 C CA  . TRP D 2 30  ? -19.57852 49.40346 15.40940  1.000 49.45956  ? 28  TRP B CA  1 
ATOM   5077 C C   . TRP D 2 30  ? -20.38505 50.52186 14.76134  1.000 50.98318  ? 28  TRP B C   1 
ATOM   5078 O O   . TRP D 2 30  ? -19.82394 51.50227 14.25929  1.000 45.32450  ? 28  TRP B O   1 
ATOM   5079 C CB  . TRP D 2 30  ? -18.89071 49.93085 16.66669  1.000 44.10887  ? 28  TRP B CB  1 
ATOM   5080 C CG  . TRP D 2 30  ? -19.83486 50.51697 17.66087  1.000 48.29712  ? 28  TRP B CG  1 
ATOM   5081 C CD1 . TRP D 2 30  ? -19.91503 51.82466 18.04975  1.000 53.86848  ? 28  TRP B CD1 1 
ATOM   5082 C CD2 . TRP D 2 30  ? -20.83954 49.81506 18.39755  1.000 49.04589  ? 28  TRP B CD2 1 
ATOM   5083 N NE1 . TRP D 2 30  ? -20.90330 51.97765 18.99265  1.000 55.13477  ? 28  TRP B NE1 1 
ATOM   5084 C CE2 . TRP D 2 30  ? -21.48908 50.75991 19.22198  1.000 57.72776  ? 28  TRP B CE2 1 
ATOM   5085 C CE3 . TRP D 2 30  ? -21.25040 48.47724 18.44513  1.000 46.84837  ? 28  TRP B CE3 1 
ATOM   5086 C CZ2 . TRP D 2 30  ? -22.52733 50.40903 20.08645  1.000 50.64914  ? 28  TRP B CZ2 1 
ATOM   5087 C CZ3 . TRP D 2 30  ? -22.27868 48.12870 19.30000  1.000 44.01341  ? 28  TRP B CZ3 1 
ATOM   5088 C CH2 . TRP D 2 30  ? -22.90610 49.09200 20.11120  1.000 52.24327  ? 28  TRP B CH2 1 
ATOM   5089 N N   . ARG D 2 31  ? -21.71220 50.36458 14.78461  1.000 48.63312  ? 29  ARG B N   1 
ATOM   5090 C CA  . ARG D 2 31  ? -22.65732 51.31937 14.20785  1.000 48.44386  ? 29  ARG B CA  1 
ATOM   5091 C C   . ARG D 2 31  ? -22.38648 51.57307 12.72974  1.000 49.91146  ? 29  ARG B C   1 
ATOM   5092 O O   . ARG D 2 31  ? -22.84410 52.57946 12.17843  1.000 47.50438  ? 29  ARG B O   1 
ATOM   5093 C CB  . ARG D 2 31  ? -22.65544 52.64316 14.98600  1.000 56.10695  ? 29  ARG B CB  1 
ATOM   5094 C CG  . ARG D 2 31  ? -23.66183 52.70539 16.14018  1.000 68.78608  ? 29  ARG B CG  1 
ATOM   5095 C CD  . ARG D 2 31  ? -23.09114 53.41038 17.36742  1.000 66.79336  ? 29  ARG B CD  1 
ATOM   5096 N NE  . ARG D 2 31  ? -22.55042 54.73488 17.08014  1.000 77.28383  ? 29  ARG B NE  1 
ATOM   5097 C CZ  . ARG D 2 31  ? -23.08191 55.87224 17.51009  1.000 84.70714  ? 29  ARG B CZ  1 
ATOM   5098 N NH1 . ARG D 2 31  ? -24.17582 55.88601 18.25768  1.000 85.62714  ? 29  ARG B NH1 1 
ATOM   5099 N NH2 . ARG D 2 31  ? -22.49782 57.02438 17.18746  1.000 80.52041  ? 29  ARG B NH2 1 
ATOM   5100 N N   . ASN D 2 32  ? -21.65053 50.66129 12.08628  1.000 46.76983  ? 30  ASN B N   1 
ATOM   5101 C CA  . ASN D 2 32  ? -21.18666 50.81482 10.71046  1.000 52.66478  ? 30  ASN B CA  1 
ATOM   5102 C C   . ASN D 2 32  ? -20.62717 52.21293 10.47003  1.000 54.93695  ? 30  ASN B C   1 
ATOM   5103 O O   . ASN D 2 32  ? -20.92945 52.84399 9.45126   1.000 56.37318  ? 30  ASN B O   1 
ATOM   5104 C CB  . ASN D 2 32  ? -22.31524 50.51867 9.71932   1.000 50.24964  ? 30  ASN B CB  1 
ATOM   5105 C CG  . ASN D 2 32  ? -21.79412 50.12575 8.34975   1.000 57.66311  ? 30  ASN B CG  1 
ATOM   5106 O OD1 . ASN D 2 32  ? -20.64192 50.40148 8.00809   1.000 57.39240  ? 30  ASN B OD1 1 
ATOM   5107 N ND2 . ASN D 2 32  ? -22.63791 49.47344 7.55916   1.000 66.15780  ? 30  ASN B ND2 1 
ATOM   5108 N N   . LYS D 2 33  ? -19.82030 52.71355 11.40412  1.000 48.06559  ? 31  LYS B N   1 
ATOM   5109 C CA  . LYS D 2 33  ? -19.29993 54.06653 11.26460  1.000 50.15792  ? 31  LYS B CA  1 
ATOM   5110 C C   . LYS D 2 33  ? -17.89355 54.19267 11.83314  1.000 47.05467  ? 31  LYS B C   1 
ATOM   5111 O O   . LYS D 2 33  ? -17.12201 55.03982 11.37565  1.000 44.23533  ? 31  LYS B O   1 
ATOM   5112 C CB  . LYS D 2 33  ? -20.23860 55.07167 11.94467  1.000 51.35985  ? 31  LYS B CB  1 
ATOM   5113 C CG  . LYS D 2 33  ? -20.19559 56.49197 11.35897  1.000 62.63867  ? 31  LYS B CG  1 
ATOM   5114 C CD  . LYS D 2 33  ? -20.43720 56.48974 9.84459   1.000 63.09157  ? 31  LYS B CD  1 
ATOM   5115 C CE  . LYS D 2 33  ? -21.02560 57.81515 9.33791   1.000 68.24308  ? 31  LYS B CE  1 
ATOM   5116 N NZ  . LYS D 2 33  ? -20.10781 58.98161 9.48498   1.000 60.47273  ? 31  LYS B NZ  1 
ATOM   5117 N N   . ASN D 2 34  ? -17.54237 53.35102 12.81130  1.000 47.76716  ? 32  ASN B N   1 
ATOM   5118 C CA  . ASN D 2 34  ? -16.32118 53.54557 13.59574  1.000 43.39306  ? 32  ASN B CA  1 
ATOM   5119 C C   . ASN D 2 34  ? -15.12170 52.96161 12.84974  1.000 40.04990  ? 32  ASN B C   1 
ATOM   5120 O O   . ASN D 2 34  ? -14.66841 51.84347 13.10122  1.000 40.81512  ? 32  ASN B O   1 
ATOM   5121 C CB  . ASN D 2 34  ? -16.47747 52.94143 14.98799  1.000 36.31263  ? 32  ASN B CB  1 
ATOM   5122 C CG  . ASN D 2 34  ? -17.38799 53.77452 15.89576  1.000 46.94088  ? 32  ASN B CG  1 
ATOM   5123 O OD1 . ASN D 2 34  ? -18.51953 54.10700 15.52981  1.000 45.16818  ? 32  ASN B OD1 1 
ATOM   5124 N ND2 . ASN D 2 34  ? -16.88725 54.12134 17.08499  1.000 40.83898  ? 32  ASN B ND2 1 
ATOM   5125 N N   . VAL D 2 35  ? -14.59651 53.75449 11.91477  1.000 43.00860  ? 33  VAL B N   1 
ATOM   5126 C CA  . VAL D 2 35  ? -13.34896 53.46467 11.21166  1.000 38.70611  ? 33  VAL B CA  1 
ATOM   5127 C C   . VAL D 2 35  ? -12.54047 54.75102 11.15788  1.000 40.76621  ? 33  VAL B C   1 
ATOM   5128 O O   . VAL D 2 35  ? -13.07243 55.80593 10.79573  1.000 44.38914  ? 33  VAL B O   1 
ATOM   5129 C CB  . VAL D 2 35  ? -13.58579 52.92809 9.78389   1.000 39.26818  ? 33  VAL B CB  1 
ATOM   5130 C CG1 . VAL D 2 35  ? -12.27083 52.86928 9.00502   1.000 37.88804  ? 33  VAL B CG1 1 
ATOM   5131 C CG2 . VAL D 2 35  ? -14.23616 51.56634 9.81955   1.000 38.90541  ? 33  VAL B CG2 1 
ATOM   5132 N N   . ALA D 2 36  ? -11.26498 54.67414 11.52468  1.000 37.79049  ? 34  ALA B N   1 
ATOM   5133 C CA  . ALA D 2 36  ? -10.35983 55.80844 11.41968  1.000 31.80953  ? 34  ALA B CA  1 
ATOM   5134 C C   . ALA D 2 36  ? -9.16849  55.44300 10.54628  1.000 32.96437  ? 34  ALA B C   1 
ATOM   5135 O O   . ALA D 2 36  ? -8.89548  54.26635 10.29102  1.000 35.53119  ? 34  ALA B O   1 
ATOM   5136 C CB  . ALA D 2 36  ? -9.86988  56.28110 12.80434  1.000 31.05237  ? 34  ALA B CB  1 
ATOM   5137 N N   . TRP D 2 37  ? -8.47169  56.47537 10.07039  1.000 37.93723  ? 35  TRP B N   1 
ATOM   5138 C CA  . TRP D 2 37  ? -7.24332  56.32491 9.29685   1.000 34.02911  ? 35  TRP B CA  1 
ATOM   5139 C C   . TRP D 2 37  ? -6.12951  57.11624 9.96832   1.000 32.66955  ? 35  TRP B C   1 
ATOM   5140 O O   . TRP D 2 37  ? -6.30531  58.29770 10.29412  1.000 39.50581  ? 35  TRP B O   1 
ATOM   5141 C CB  . TRP D 2 37  ? -7.42605  56.80306 7.85906   1.000 32.55692  ? 35  TRP B CB  1 
ATOM   5142 C CG  . TRP D 2 37  ? -8.23688  55.89272 6.99648   1.000 37.40697  ? 35  TRP B CG  1 
ATOM   5143 C CD1 . TRP D 2 37  ? -9.55747  56.01831 6.69465   1.000 37.09003  ? 35  TRP B CD1 1 
ATOM   5144 C CD2 . TRP D 2 37  ? -7.77585  54.72327 6.30357   1.000 33.33518  ? 35  TRP B CD2 1 
ATOM   5145 N NE1 . TRP D 2 37  ? -9.95208  54.99907 5.86238   1.000 42.62919  ? 35  TRP B NE1 1 
ATOM   5146 C CE2 . TRP D 2 37  ? -8.87625  54.19329 5.60273   1.000 31.86834  ? 35  TRP B CE2 1 
ATOM   5147 C CE3 . TRP D 2 37  ? -6.54063  54.07254 6.21122   1.000 32.61592  ? 35  TRP B CE3 1 
ATOM   5148 C CZ2 . TRP D 2 37  ? -8.78247  53.04025 4.82028   1.000 32.41893  ? 35  TRP B CZ2 1 
ATOM   5149 C CZ3 . TRP D 2 37  ? -6.44499  52.93309 5.41744   1.000 40.46503  ? 35  TRP B CZ3 1 
ATOM   5150 C CH2 . TRP D 2 37  ? -7.56118  52.42997 4.73624   1.000 38.39469  ? 35  TRP B CH2 1 
ATOM   5151 N N   . TYR D 2 38  ? -4.98735  56.46864 10.16201  1.000 30.05950  ? 36  TYR B N   1 
ATOM   5152 C CA  . TYR D 2 38  ? -3.86141  57.04032 10.88091  1.000 33.53251  ? 36  TYR B CA  1 
ATOM   5153 C C   . TYR D 2 38  ? -2.64403  57.14013 9.97385   1.000 36.97009  ? 36  TYR B C   1 
ATOM   5154 O O   . TYR D 2 38  ? -2.42066  56.28890 9.11145   1.000 35.42698  ? 36  TYR B O   1 
ATOM   5155 C CB  . TYR D 2 38  ? -3.51793  56.20130 12.11069  1.000 31.36874  ? 36  TYR B CB  1 
ATOM   5156 C CG  . TYR D 2 38  ? -4.31056  56.57791 13.33983  1.000 29.79267  ? 36  TYR B CG  1 
ATOM   5157 C CD1 . TYR D 2 38  ? -5.59005  56.08028 13.54933  1.000 31.77348  ? 36  TYR B CD1 1 
ATOM   5158 C CD2 . TYR D 2 38  ? -3.77064  57.43202 14.29263  1.000 29.98600  ? 36  TYR B CD2 1 
ATOM   5159 C CE1 . TYR D 2 38  ? -6.31509  56.42943 14.68293  1.000 30.75459  ? 36  TYR B CE1 1 
ATOM   5160 C CE2 . TYR D 2 38  ? -4.48054  57.79563 15.41727  1.000 35.05554  ? 36  TYR B CE2 1 
ATOM   5161 C CZ  . TYR D 2 38  ? -5.75071  57.29236 15.61420  1.000 37.19479  ? 36  TYR B CZ  1 
ATOM   5162 O OH  . TYR D 2 38  ? -6.44573  57.65456 16.75068  1.000 36.22969  ? 36  TYR B OH  1 
ATOM   5163 N N   . GLN D 2 39  ? -1.84876  58.18617 10.18880  1.000 36.57511  ? 37  GLN B N   1 
ATOM   5164 C CA  . GLN D 2 39  ? -0.61061  58.41454 9.45112   1.000 37.79656  ? 37  GLN B CA  1 
ATOM   5165 C C   . GLN D 2 39  ? 0.55629   58.43108 10.42748  1.000 33.31513  ? 37  GLN B C   1 
ATOM   5166 O O   . GLN D 2 39  ? 0.50970   59.13437 11.44237  1.000 36.44917  ? 37  GLN B O   1 
ATOM   5167 C CB  . GLN D 2 39  ? -0.67501  59.73472 8.68361   1.000 37.47391  ? 37  GLN B CB  1 
ATOM   5168 C CG  . GLN D 2 39  ? 0.61664   60.15320 8.02502   1.000 37.53772  ? 37  GLN B CG  1 
ATOM   5169 C CD  . GLN D 2 39  ? 0.54429   61.58265 7.55184   1.000 46.73633  ? 37  GLN B CD  1 
ATOM   5170 O OE1 . GLN D 2 39  ? 0.21329   62.49195 8.32690   1.000 45.47871  ? 37  GLN B OE1 1 
ATOM   5171 N NE2 . GLN D 2 39  ? 0.82382   61.79626 6.26863   1.000 46.09780  ? 37  GLN B NE2 1 
ATOM   5172 N N   . GLN D 2 40  ? 1.59624   57.65751 10.13351  1.000 30.96971  ? 38  GLN B N   1 
ATOM   5173 C CA  . GLN D 2 40  ? 2.78925   57.64816 10.96538  1.000 34.34102  ? 38  GLN B CA  1 
ATOM   5174 C C   . GLN D 2 40  ? 4.00401   58.02164 10.13332  1.000 44.75229  ? 38  GLN B C   1 
ATOM   5175 O O   . GLN D 2 40  ? 4.40276   57.27260 9.23658   1.000 42.26194  ? 38  GLN B O   1 
ATOM   5176 C CB  . GLN D 2 40  ? 3.01351   56.29261 11.62372  1.000 34.06316  ? 38  GLN B CB  1 
ATOM   5177 C CG  . GLN D 2 40  ? 4.07087   56.37942 12.70508  1.000 33.82507  ? 38  GLN B CG  1 
ATOM   5178 C CD  . GLN D 2 40  ? 4.14670   55.12987 13.52012  1.000 34.75654  ? 38  GLN B CD  1 
ATOM   5179 O OE1 . GLN D 2 40  ? 3.86738   54.04355 13.01933  1.000 38.33220  ? 38  GLN B OE1 1 
ATOM   5180 N NE2 . GLN D 2 40  ? 4.52581   55.26590 14.79085  1.000 34.91280  ? 38  GLN B NE2 1 
ATOM   5181 N N   . LYS D 2 41  ? 4.59517   59.14938 10.44918  1.000 36.11398  ? 39  LYS B N   1 
ATOM   5182 C CA  . LYS D 2 41  ? 5.84905   59.55926 9.84945   1.000 35.45076  ? 39  LYS B CA  1 
ATOM   5183 C C   . LYS D 2 41  ? 7.01324   58.94167 10.61345  1.000 43.23717  ? 39  LYS B C   1 
ATOM   5184 O O   . LYS D 2 41  ? 6.84833   58.48661 11.74917  1.000 47.06715  ? 39  LYS B O   1 
ATOM   5185 C CB  . LYS D 2 41  ? 5.92825   61.08661 9.83537   1.000 36.80672  ? 39  LYS B CB  1 
ATOM   5186 C CG  . LYS D 2 41  ? 4.72705   61.69431 9.12375   1.000 43.75362  ? 39  LYS B CG  1 
ATOM   5187 C CD  . LYS D 2 41  ? 4.93633   63.13386 8.69956   1.000 58.35269  ? 39  LYS B CD  1 
ATOM   5188 C CE  . LYS D 2 41  ? 3.81832   63.57161 7.75632   1.000 51.80278  ? 39  LYS B CE  1 
ATOM   5189 N NZ  . LYS D 2 41  ? 3.99191   64.95593 7.21110   1.000 50.47433  ? 39  LYS B NZ  1 
ATOM   5190 N N   . PRO D 2 42  ? 8.19686   58.86764 10.00290  1.000 50.00599  ? 40  PRO B N   1 
ATOM   5191 C CA  . PRO D 2 42  ? 9.33911   58.22879 10.67580  1.000 46.54959  ? 40  PRO B CA  1 
ATOM   5192 C C   . PRO D 2 42  ? 9.68013   58.91084 11.99295  1.000 45.69271  ? 40  PRO B C   1 
ATOM   5193 O O   . PRO D 2 42  ? 9.72533   60.14015 12.08497  1.000 45.00782  ? 40  PRO B O   1 
ATOM   5194 C CB  . PRO D 2 42  ? 10.47392  58.37577 9.65660   1.000 42.94080  ? 40  PRO B CB  1 
ATOM   5195 C CG  . PRO D 2 42  ? 9.78557   58.45072 8.35255   1.000 34.40730  ? 40  PRO B CG  1 
ATOM   5196 C CD  . PRO D 2 42  ? 8.50828   59.20623 8.60311   1.000 46.71304  ? 40  PRO B CD  1 
ATOM   5197 N N   . GLY D 2 43  ? 9.91577   58.09448 13.01896  1.000 46.33871  ? 41  GLY B N   1 
ATOM   5198 C CA  . GLY D 2 43  ? 10.24519  58.59215 14.33812  1.000 40.04065  ? 41  GLY B CA  1 
ATOM   5199 C C   . GLY D 2 43  ? 9.11461   59.25497 15.09320  1.000 45.65486  ? 41  GLY B C   1 
ATOM   5200 O O   . GLY D 2 43  ? 9.33831   59.73444 16.21065  1.000 42.57980  ? 41  GLY B O   1 
ATOM   5201 N N   . LYS D 2 44  ? 7.90968   59.30257 14.54049  1.000 42.29606  ? 42  LYS B N   1 
ATOM   5202 C CA  . LYS D 2 44  ? 6.83495   60.05911 15.15565  1.000 33.10004  ? 42  LYS B CA  1 
ATOM   5203 C C   . LYS D 2 44  ? 5.71129   59.12602 15.57880  1.000 38.06571  ? 42  LYS B C   1 
ATOM   5204 O O   . LYS D 2 44  ? 5.65654   57.95866 15.19014  1.000 35.87202  ? 42  LYS B O   1 
ATOM   5205 C CB  . LYS D 2 44  ? 6.32013   61.14418 14.20701  1.000 39.51650  ? 42  LYS B CB  1 
ATOM   5206 C CG  . LYS D 2 44  ? 7.41427   62.09060 13.76477  1.000 44.32837  ? 42  LYS B CG  1 
ATOM   5207 C CD  . LYS D 2 44  ? 7.00747   63.54051 13.95625  1.000 55.77908  ? 42  LYS B CD  1 
ATOM   5208 C CE  . LYS D 2 44  ? 8.20621   64.47319 13.78989  1.000 57.73559  ? 42  LYS B CE  1 
ATOM   5209 N NZ  . LYS D 2 44  ? 8.92996   64.24640 12.50052  1.000 62.87705  ? 42  LYS B NZ  1 
ATOM   5210 N N   . ALA D 2 45  ? 4.82088   59.65029 16.40607  1.000 32.42751  ? 43  ALA B N   1 
ATOM   5211 C CA  . ALA D 2 45  ? 3.69063   58.86001 16.84852  1.000 41.03168  ? 43  ALA B CA  1 
ATOM   5212 C C   . ALA D 2 45  ? 2.58347   58.91068 15.80309  1.000 39.62570  ? 43  ALA B C   1 
ATOM   5213 O O   . ALA D 2 45  ? 2.53505   59.83104 14.97944  1.000 36.09152  ? 43  ALA B O   1 
ATOM   5214 C CB  . ALA D 2 45  ? 3.18514   59.36763 18.19343  1.000 36.18744  ? 43  ALA B CB  1 
ATOM   5215 N N   . PRO D 2 46  ? 1.69301   57.91961 15.79966  1.000 39.67465  ? 44  PRO B N   1 
ATOM   5216 C CA  . PRO D 2 46  ? 0.58946   57.92986 14.83575  1.000 34.07328  ? 44  PRO B CA  1 
ATOM   5217 C C   . PRO D 2 46  ? -0.30808  59.14399 15.01372  1.000 40.08921  ? 44  PRO B C   1 
ATOM   5218 O O   . PRO D 2 46  ? -0.55607  59.61122 16.12804  1.000 40.53229  ? 44  PRO B O   1 
ATOM   5219 C CB  . PRO D 2 46  ? -0.15757  56.62733 15.14558  1.000 34.65242  ? 44  PRO B CB  1 
ATOM   5220 C CG  . PRO D 2 46  ? 0.89626   55.73935 15.69718  1.000 30.70027  ? 44  PRO B CG  1 
ATOM   5221 C CD  . PRO D 2 46  ? 1.73944   56.64941 16.54730  1.000 36.95982  ? 44  PRO B CD  1 
ATOM   5222 N N   . LYS D 2 47  ? -0.80570  59.64279 13.88637  1.000 28.55369  ? 45  LYS B N   1 
ATOM   5223 C CA  . LYS D 2 47  ? -1.59111  60.86732 13.81289  1.000 36.09888  ? 45  LYS B CA  1 
ATOM   5224 C C   . LYS D 2 47  ? -2.88465  60.55816 13.07561  1.000 39.06866  ? 45  LYS B C   1 
ATOM   5225 O O   . LYS D 2 47  ? -2.84831  59.98801 11.97925  1.000 36.82950  ? 45  LYS B O   1 
ATOM   5226 C CB  . LYS D 2 47  ? -0.78183  61.95541 13.09087  1.000 40.69832  ? 45  LYS B CB  1 
ATOM   5227 C CG  . LYS D 2 47  ? -1.50372  63.25400 12.73688  1.000 48.84079  ? 45  LYS B CG  1 
ATOM   5228 C CD  . LYS D 2 47  ? -0.62468  64.05720 11.75012  1.000 60.77961  ? 45  LYS B CD  1 
ATOM   5229 C CE  . LYS D 2 47  ? -0.87097  65.56352 11.79319  1.000 57.36161  ? 45  LYS B CE  1 
ATOM   5230 N NZ  . LYS D 2 47  ? -2.21944  65.96193 11.30430  1.000 60.54765  ? 45  LYS B NZ  1 
ATOM   5231 N N   . ARG D 2 48  ? -4.02320  60.91403 13.67296  1.000 29.52156  ? 46  ARG B N   1 
ATOM   5232 C CA  . ARG D 2 48  ? -5.31189  60.56558 13.08035  1.000 36.88490  ? 46  ARG B CA  1 
ATOM   5233 C C   . ARG D 2 48  ? -5.70789  61.57103 12.00486  1.000 40.02104  ? 46  ARG B C   1 
ATOM   5234 O O   . ARG D 2 48  ? -5.77268  62.77648 12.26231  1.000 40.37068  ? 46  ARG B O   1 
ATOM   5235 C CB  . ARG D 2 48  ? -6.40561  60.50197 14.14374  1.000 37.81152  ? 46  ARG B CB  1 
ATOM   5236 C CG  . ARG D 2 48  ? -7.72409  59.98750 13.58243  1.000 38.23216  ? 46  ARG B CG  1 
ATOM   5237 C CD  . ARG D 2 48  ? -8.85823  60.09523 14.57266  1.000 39.25755  ? 46  ARG B CD  1 
ATOM   5238 N NE  . ARG D 2 48  ? -9.18748  61.48370 14.86883  1.000 39.20583  ? 46  ARG B NE  1 
ATOM   5239 C CZ  . ARG D 2 48  ? -10.30407 61.87291 15.46839  1.000 46.48573  ? 46  ARG B CZ  1 
ATOM   5240 N NH1 . ARG D 2 48  ? -11.22516 61.00209 15.84435  1.000 38.62487  ? 46  ARG B NH1 1 
ATOM   5241 N NH2 . ARG D 2 48  ? -10.50218 63.16910 15.69380  1.000 43.19239  ? 46  ARG B NH2 1 
ATOM   5242 N N   . LEU D 2 49  ? -5.99555  61.07305 10.80486  1.000 37.36927  ? 47  LEU B N   1 
ATOM   5243 C CA  . LEU D 2 49  ? -6.44095  61.91526 9.69911   1.000 40.92918  ? 47  LEU B CA  1 
ATOM   5244 C C   . LEU D 2 49  ? -7.95514  61.92052 9.54193   1.000 42.79545  ? 47  LEU B C   1 
ATOM   5245 O O   . LEU D 2 49  ? -8.56452  62.98239 9.38607   1.000 48.81407  ? 47  LEU B O   1 
ATOM   5246 C CB  . LEU D 2 49  ? -5.79997  61.44037 8.39251   1.000 41.79073  ? 47  LEU B CB  1 
ATOM   5247 C CG  . LEU D 2 49  ? -4.28534  61.28243 8.45151   1.000 38.54674  ? 47  LEU B CG  1 
ATOM   5248 C CD1 . LEU D 2 49  ? -3.77584  60.68705 7.15995   1.000 45.76606  ? 47  LEU B CD1 1 
ATOM   5249 C CD2 . LEU D 2 49  ? -3.62395  62.62265 8.74155   1.000 43.98515  ? 47  LEU B CD2 1 
ATOM   5250 N N   . ILE D 2 50  ? -8.56819  60.74099 9.58283   1.000 36.81376  ? 48  ILE B N   1 
ATOM   5251 C CA  . ILE D 2 50  ? -9.97474  60.53517 9.26382   1.000 41.17382  ? 48  ILE B CA  1 
ATOM   5252 C C   . ILE D 2 50  ? -10.60755 59.77430 10.41515  1.000 39.67789  ? 48  ILE B C   1 
ATOM   5253 O O   . ILE D 2 50  ? -9.95963  58.92094 11.02988  1.000 39.81373  ? 48  ILE B O   1 
ATOM   5254 C CB  . ILE D 2 50  ? -10.14441 59.74177 7.94721   1.000 45.04976  ? 48  ILE B CB  1 
ATOM   5255 C CG1 . ILE D 2 50  ? -9.48001  60.47204 6.77211   1.000 48.70738  ? 48  ILE B CG1 1 
ATOM   5256 C CG2 . ILE D 2 50  ? -11.61989 59.45959 7.65588   1.000 39.16510  ? 48  ILE B CG2 1 
ATOM   5257 C CD1 . ILE D 2 50  ? -10.28240 61.62883 6.24418   1.000 49.85386  ? 48  ILE B CD1 1 
ATOM   5258 N N   . TYR D 2 51  ? -11.86706 60.08004 10.70988  1.000 37.17887  ? 49  TYR B N   1 
ATOM   5259 C CA  . TYR D 2 51  ? -12.62596 59.32567 11.69212  1.000 41.08594  ? 49  TYR B CA  1 
ATOM   5260 C C   . TYR D 2 51  ? -14.05557 59.19470 11.19523  1.000 45.41201  ? 49  TYR B C   1 
ATOM   5261 O O   . TYR D 2 51  ? -14.49457 59.93589 10.31131  1.000 49.65856  ? 49  TYR B O   1 
ATOM   5262 C CB  . TYR D 2 51  ? -12.58358 59.98508 13.08012  1.000 46.60715  ? 49  TYR B CB  1 
ATOM   5263 C CG  . TYR D 2 51  ? -13.29883 61.32072 13.15794  1.000 45.34181  ? 49  TYR B CG  1 
ATOM   5264 C CD1 . TYR D 2 51  ? -12.66349 62.49611 12.77465  1.000 44.33966  ? 49  TYR B CD1 1 
ATOM   5265 C CD2 . TYR D 2 51  ? -14.60563 61.40325 13.62487  1.000 45.54200  ? 49  TYR B CD2 1 
ATOM   5266 C CE1 . TYR D 2 51  ? -13.31441 63.71615 12.84661  1.000 48.82682  ? 49  TYR B CE1 1 
ATOM   5267 C CE2 . TYR D 2 51  ? -15.26427 62.61586 13.70010  1.000 48.29301  ? 49  TYR B CE2 1 
ATOM   5268 C CZ  . TYR D 2 51  ? -14.61488 63.76838 13.31113  1.000 48.67751  ? 49  TYR B CZ  1 
ATOM   5269 O OH  . TYR D 2 51  ? -15.26633 64.97628 13.38219  1.000 51.60884  ? 49  TYR B OH  1 
ATOM   5270 N N   . ALA D 2 52  ? -14.77851 58.23304 11.76894  1.000 43.35906  ? 50  ALA B N   1 
ATOM   5271 C CA  . ALA D 2 52  ? -16.16311 57.96809 11.38350  1.000 43.03629  ? 50  ALA B CA  1 
ATOM   5272 C C   . ALA D 2 52  ? -16.27281 57.71545 9.87933   1.000 50.28952  ? 50  ALA B C   1 
ATOM   5273 O O   . ALA D 2 52  ? -17.17677 58.21858 9.20630   1.000 50.13637  ? 50  ALA B O   1 
ATOM   5274 C CB  . ALA D 2 52  ? -17.08359 59.10859 11.82440  1.000 40.20637  ? 50  ALA B CB  1 
ATOM   5275 N N   . ILE D 2 53  ? -15.31740 56.94149 9.35295   1.000 45.00002  ? 51  ILE B N   1 
ATOM   5276 C CA  . ILE D 2 53  ? -15.22653 56.54337 7.94958   1.000 39.26376  ? 51  ILE B CA  1 
ATOM   5277 C C   . ILE D 2 53  ? -14.78852 57.69836 7.05508   1.000 50.47772  ? 51  ILE B C   1 
ATOM   5278 O O   . ILE D 2 53  ? -13.88563 57.54348 6.22048   1.000 46.23836  ? 51  ILE B O   1 
ATOM   5279 C CB  . ILE D 2 53  ? -16.55080 55.95514 7.43694   1.000 45.08485  ? 51  ILE B CB  1 
ATOM   5280 C CG1 . ILE D 2 53  ? -16.90485 54.68923 8.21558   1.000 47.86048  ? 51  ILE B CG1 1 
ATOM   5281 C CG2 . ILE D 2 53  ? -16.46547 55.70417 5.92313   1.000 45.95714  ? 51  ILE B CG2 1 
ATOM   5282 C CD1 . ILE D 2 53  ? -18.19709 54.04000 7.77650   1.000 46.12314  ? 51  ILE B CD1 1 
ATOM   5283 N N   . ALA D 2 54  ? -15.42902 58.85802 7.20012   1.000 46.98736  ? 52  ALA B N   1 
ATOM   5284 C CA  . ALA D 2 54  ? -15.23284 59.92777 6.23180   1.000 43.61365  ? 52  ALA B CA  1 
ATOM   5285 C C   . ALA D 2 54  ? -15.06711 61.31791 6.82763   1.000 47.87590  ? 52  ALA B C   1 
ATOM   5286 O O   . ALA D 2 54  ? -14.90815 62.27229 6.06186   1.000 39.90874  ? 52  ALA B O   1 
ATOM   5287 C CB  . ALA D 2 54  ? -16.40652 59.95549 5.23799   1.000 42.39796  ? 52  ALA B CB  1 
ATOM   5288 N N   . SER D 2 55  ? -15.11041 61.47865 8.14566   1.000 41.55948  ? 53  SER B N   1 
ATOM   5289 C CA  . SER D 2 55  ? -14.98797 62.80618 8.73636   1.000 40.16989  ? 53  SER B CA  1 
ATOM   5290 C C   . SER D 2 55  ? -13.51766 63.20009 8.80195   1.000 47.93569  ? 53  SER B C   1 
ATOM   5291 O O   . SER D 2 55  ? -12.69700 62.48176 9.38683   1.000 46.46285  ? 53  SER B O   1 
ATOM   5292 C CB  . SER D 2 55  ? -15.62168 62.84079 10.12861  1.000 40.16133  ? 53  SER B CB  1 
ATOM   5293 O OG  . SER D 2 55  ? -17.01732 62.62189 10.06109  1.000 39.08114  ? 53  SER B OG  1 
ATOM   5294 N N   . LEU D 2 56  ? -13.18073 64.33405 8.20215   1.000 45.00371  ? 54  LEU B N   1 
ATOM   5295 C CA  . LEU D 2 56  ? -11.82523 64.84947 8.26650   1.000 40.00974  ? 54  LEU B CA  1 
ATOM   5296 C C   . LEU D 2 56  ? -11.68022 65.70217 9.51832   1.000 52.79628  ? 54  LEU B C   1 
ATOM   5297 O O   . LEU D 2 56  ? -12.47962 66.61367 9.75608   1.000 56.95235  ? 54  LEU B O   1 
ATOM   5298 C CB  . LEU D 2 56  ? -11.49289 65.66465 7.01404   1.000 54.59546  ? 54  LEU B CB  1 
ATOM   5299 C CG  . LEU D 2 56  ? -10.04253 66.13563 6.85039   1.000 59.77546  ? 54  LEU B CG  1 
ATOM   5300 C CD1 . LEU D 2 56  ? -9.10144  64.95105 6.72516   1.000 54.02323  ? 54  LEU B CD1 1 
ATOM   5301 C CD2 . LEU D 2 56  ? -9.89606  67.06643 5.64618   1.000 56.15031  ? 54  LEU B CD2 1 
ATOM   5302 N N   . TYR D 2 57  ? -10.67984 65.38576 10.32883  1.000 49.37048  ? 55  TYR B N   1 
ATOM   5303 C CA  . TYR D 2 57  ? -10.38630 66.20872 11.49014  1.000 51.08785  ? 55  TYR B CA  1 
ATOM   5304 C C   . TYR D 2 57  ? -9.87002  67.56712 11.02804  1.000 52.89907  ? 55  TYR B C   1 
ATOM   5305 O O   . TYR D 2 57  ? -9.17586  67.66824 10.01234  1.000 53.86710  ? 55  TYR B O   1 
ATOM   5306 C CB  . TYR D 2 57  ? -9.36232  65.50750 12.38303  1.000 47.69672  ? 55  TYR B CB  1 
ATOM   5307 C CG  . TYR D 2 57  ? -9.09468  66.22542 13.68497  1.000 55.01813  ? 55  TYR B CG  1 
ATOM   5308 C CD1 . TYR D 2 57  ? -10.07997 66.31770 14.66540  1.000 51.43766  ? 55  TYR B CD1 1 
ATOM   5309 C CD2 . TYR D 2 57  ? -7.86001  66.80829 13.93567  1.000 47.74116  ? 55  TYR B CD2 1 
ATOM   5310 C CE1 . TYR D 2 57  ? -9.84256  66.97011 15.85688  1.000 47.60519  ? 55  TYR B CE1 1 
ATOM   5311 C CE2 . TYR D 2 57  ? -7.61476  67.46906 15.12319  1.000 60.61630  ? 55  TYR B CE2 1 
ATOM   5312 C CZ  . TYR D 2 57  ? -8.60939  67.54553 16.08083  1.000 54.10747  ? 55  TYR B CZ  1 
ATOM   5313 O OH  . TYR D 2 57  ? -8.36545  68.20300 17.26629  1.000 61.95801  ? 55  TYR B OH  1 
ATOM   5314 N N   . SER D 2 58  ? -10.22498 68.61912 11.76301  1.000 48.56465  ? 56  SER B N   1 
ATOM   5315 C CA  . SER D 2 58  ? -9.84248  69.96153 11.34558  1.000 49.25025  ? 56  SER B CA  1 
ATOM   5316 C C   . SER D 2 58  ? -8.32443  70.10665 11.34597  1.000 55.67288  ? 56  SER B C   1 
ATOM   5317 O O   . SER D 2 58  ? -7.62694  69.55930 12.20600  1.000 46.94967  ? 56  SER B O   1 
ATOM   5318 C CB  . SER D 2 58  ? -10.47574 71.01272 12.25802  1.000 67.24984  ? 56  SER B CB  1 
ATOM   5319 O OG  . SER D 2 58  ? -9.66679  71.25771 13.39868  1.000 64.81986  ? 56  SER B OG  1 
ATOM   5320 N N   . GLY D 2 59  ? -7.81099  70.83484 10.35544  1.000 62.80310  ? 57  GLY B N   1 
ATOM   5321 C CA  . GLY D 2 59  ? -6.38461  71.03626 10.22244  1.000 60.79713  ? 57  GLY B CA  1 
ATOM   5322 C C   . GLY D 2 59  ? -5.63750  69.91300 9.54035   1.000 54.43295  ? 57  GLY B C   1 
ATOM   5323 O O   . GLY D 2 59  ? -4.40052  69.95545 9.48702   1.000 51.02698  ? 57  GLY B O   1 
ATOM   5324 N N   . VAL D 2 60  ? -6.33582  68.90566 9.04150   1.000 51.34890  ? 58  VAL B N   1 
ATOM   5325 C CA  . VAL D 2 60  ? -5.73717  67.84004 8.24218   1.000 51.51411  ? 58  VAL B CA  1 
ATOM   5326 C C   . VAL D 2 60  ? -5.92475  68.20353 6.77228   1.000 49.51821  ? 58  VAL B C   1 
ATOM   5327 O O   . VAL D 2 60  ? -7.03830  68.59005 6.38485   1.000 43.81964  ? 58  VAL B O   1 
ATOM   5328 C CB  . VAL D 2 60  ? -6.37018  66.47135 8.55854   1.000 55.40361  ? 58  VAL B CB  1 
ATOM   5329 C CG1 . VAL D 2 60  ? -5.73295  65.36855 7.71742   1.000 46.51807  ? 58  VAL B CG1 1 
ATOM   5330 C CG2 . VAL D 2 60  ? -6.24044  66.15082 10.04562  1.000 54.25125  ? 58  VAL B CG2 1 
ATOM   5331 N N   . PRO D 2 61  ? -4.88373  68.11469 5.94195   1.000 50.56075  ? 59  PRO B N   1 
ATOM   5332 C CA  . PRO D 2 61  ? -5.00146  68.55868 4.54279   1.000 48.73597  ? 59  PRO B CA  1 
ATOM   5333 C C   . PRO D 2 61  ? -6.18188  67.91496 3.82824   1.000 52.10062  ? 59  PRO B C   1 
ATOM   5334 O O   . PRO D 2 61  ? -6.39641  66.70178 3.90700   1.000 59.16517  ? 59  PRO B O   1 
ATOM   5335 C CB  . PRO D 2 61  ? -3.66512  68.12920 3.92420   1.000 48.83012  ? 59  PRO B CB  1 
ATOM   5336 C CG  . PRO D 2 61  ? -2.71151  68.08755 5.07121   1.000 50.48852  ? 59  PRO B CG  1 
ATOM   5337 C CD  . PRO D 2 61  ? -3.51905  67.65966 6.27189   1.000 48.40905  ? 59  PRO B CD  1 
ATOM   5338 N N   . SER D 2 62  ? -6.95463  68.74250 3.12342   1.000 44.60602  ? 60  SER B N   1 
ATOM   5339 C CA  . SER D 2 62  ? -8.16162  68.28357 2.44058   1.000 52.44517  ? 60  SER B CA  1 
ATOM   5340 C C   . SER D 2 62  ? -7.87731  67.41806 1.21490   1.000 50.68983  ? 60  SER B C   1 
ATOM   5341 O O   . SER D 2 62  ? -8.83007  67.03677 0.52269   1.000 44.70616  ? 60  SER B O   1 
ATOM   5342 C CB  . SER D 2 62  ? -9.01775  69.48165 2.02691   1.000 51.56247  ? 60  SER B CB  1 
ATOM   5343 O OG  . SER D 2 62  ? -8.35495  70.26047 1.04268   1.000 65.37149  ? 60  SER B OG  1 
ATOM   5344 N N   . ARG D 2 63  ? -6.61256  67.10868 0.91373   1.000 56.50039  ? 61  ARG B N   1 
ATOM   5345 C CA  . ARG D 2 63  ? -6.31628  66.12480 -0.12305  1.000 53.41456  ? 61  ARG B CA  1 
ATOM   5346 C C   . ARG D 2 63  ? -6.46482  64.69259 0.37909   1.000 53.61453  ? 61  ARG B C   1 
ATOM   5347 O O   . ARG D 2 63  ? -6.33305  63.75289 -0.41320  1.000 49.09684  ? 61  ARG B O   1 
ATOM   5348 C CB  . ARG D 2 63  ? -4.90734  66.34269 -0.67876  1.000 49.80353  ? 61  ARG B CB  1 
ATOM   5349 C CG  . ARG D 2 63  ? -3.79454  66.19685 0.33813   1.000 49.49599  ? 61  ARG B CG  1 
ATOM   5350 C CD  . ARG D 2 63  ? -2.45329  66.03921 -0.36131  1.000 56.89404  ? 61  ARG B CD  1 
ATOM   5351 N NE  . ARG D 2 63  ? -1.36726  65.81124 0.58084   1.000 56.23483  ? 61  ARG B NE  1 
ATOM   5352 C CZ  . ARG D 2 63  ? -0.80623  66.76972 1.30506   1.000 55.35567  ? 61  ARG B CZ  1 
ATOM   5353 N NH1 . ARG D 2 63  ? -1.19374  68.03080 1.19760   1.000 46.89286  ? 61  ARG B NH1 1 
ATOM   5354 N NH2 . ARG D 2 63  ? 0.15893   66.45362 2.16501   1.000 54.17943  ? 61  ARG B NH2 1 
ATOM   5355 N N   . PHE D 2 64  ? -6.73247  64.51293 1.67029   1.000 56.09623  ? 62  PHE B N   1 
ATOM   5356 C CA  . PHE D 2 64  ? -7.06983  63.22152 2.24636   1.000 49.49700  ? 62  PHE B CA  1 
ATOM   5357 C C   . PHE D 2 64  ? -8.58308  63.07077 2.31905   1.000 48.62724  ? 62  PHE B C   1 
ATOM   5358 O O   . PHE D 2 64  ? -9.29646  64.02606 2.63573   1.000 55.36690  ? 62  PHE B O   1 
ATOM   5359 C CB  . PHE D 2 64  ? -6.46028  63.07825 3.63844   1.000 45.05551  ? 62  PHE B CB  1 
ATOM   5360 C CG  . PHE D 2 64  ? -4.96980  62.97530 3.62972   1.000 45.31928  ? 62  PHE B CG  1 
ATOM   5361 C CD1 . PHE D 2 64  ? -4.18216  64.11392 3.66234   1.000 41.44447  ? 62  PHE B CD1 1 
ATOM   5362 C CD2 . PHE D 2 64  ? -4.35425  61.73752 3.58230   1.000 37.08809  ? 62  PHE B CD2 1 
ATOM   5363 C CE1 . PHE D 2 64  ? -2.80507  64.02013 3.65114   1.000 48.40600  ? 62  PHE B CE1 1 
ATOM   5364 C CE2 . PHE D 2 64  ? -2.97707  61.63240 3.56961   1.000 50.41759  ? 62  PHE B CE2 1 
ATOM   5365 C CZ  . PHE D 2 64  ? -2.19856  62.77743 3.60107   1.000 52.54493  ? 62  PHE B CZ  1 
ATOM   5366 N N   . SER D 2 65  ? -9.07049  61.86844 2.01881   1.000 46.83928  ? 63  SER B N   1 
ATOM   5367 C CA  . SER D 2 65  ? -10.50146 61.59740 2.03273   1.000 47.72724  ? 63  SER B CA  1 
ATOM   5368 C C   . SER D 2 65  ? -10.73113 60.12526 2.34693   1.000 46.74952  ? 63  SER B C   1 
ATOM   5369 O O   . SER D 2 65  ? -9.93456  59.26208 1.97205   1.000 46.23691  ? 63  SER B O   1 
ATOM   5370 C CB  . SER D 2 65  ? -11.15577 61.96495 0.69578   1.000 44.36685  ? 63  SER B CB  1 
ATOM   5371 O OG  . SER D 2 65  ? -10.34119 61.56138 -0.39495  1.000 52.00058  ? 63  SER B OG  1 
ATOM   5372 N N   . GLY D 2 66  ? -11.83235 59.85182 3.03714   1.000 43.56669  ? 64  GLY B N   1 
ATOM   5373 C CA  . GLY D 2 66  ? -12.19601 58.49825 3.40814   1.000 45.98734  ? 64  GLY B CA  1 
ATOM   5374 C C   . GLY D 2 66  ? -13.57756 58.14180 2.89738   1.000 48.39672  ? 64  GLY B C   1 
ATOM   5375 O O   . GLY D 2 66  ? -14.45100 59.00232 2.77215   1.000 44.05141  ? 64  GLY B O   1 
ATOM   5376 N N   . SER D 2 67  ? -13.76724 56.85760 2.59235   1.000 42.30682  ? 65  SER B N   1 
ATOM   5377 C CA  . SER D 2 67  ? -15.05893 56.36003 2.14154   1.000 43.70434  ? 65  SER B CA  1 
ATOM   5378 C C   . SER D 2 67  ? -15.22074 54.91424 2.59166   1.000 49.03233  ? 65  SER B C   1 
ATOM   5379 O O   . SER D 2 67  ? -14.28417 54.29274 3.10326   1.000 42.16347  ? 65  SER B O   1 
ATOM   5380 C CB  . SER D 2 67  ? -15.20411 56.47553 0.61746   1.000 46.20457  ? 65  SER B CB  1 
ATOM   5381 O OG  . SER D 2 67  ? -14.11767 55.85036 -0.04558  1.000 51.45770  ? 65  SER B OG  1 
ATOM   5382 N N   . GLY D 2 68  ? -16.43266 54.39040 2.41306   1.000 41.71315  ? 66  GLY B N   1 
ATOM   5383 C CA  . GLY D 2 68  ? -16.69496 52.97733 2.54745   1.000 42.34223  ? 66  GLY B CA  1 
ATOM   5384 C C   . GLY D 2 68  ? -17.93532 52.69796 3.36388   1.000 43.64046  ? 66  GLY B C   1 
ATOM   5385 O O   . GLY D 2 68  ? -18.60126 53.59702 3.87361   1.000 44.65806  ? 66  GLY B O   1 
ATOM   5386 N N   . SER D 2 69  ? -18.23867 51.40683 3.48400   1.000 49.23916  ? 67  SER B N   1 
ATOM   5387 C CA  . SER D 2 69  ? -19.35527 50.91451 4.27951   1.000 46.20612  ? 67  SER B CA  1 
ATOM   5388 C C   . SER D 2 69  ? -19.21910 49.40531 4.42032   1.000 48.33128  ? 67  SER B C   1 
ATOM   5389 O O   . SER D 2 69  ? -18.58832 48.73834 3.59119   1.000 40.43533  ? 67  SER B O   1 
ATOM   5390 C CB  . SER D 2 69  ? -20.70643 51.27312 3.64796   1.000 56.78684  ? 67  SER B CB  1 
ATOM   5391 O OG  . SER D 2 69  ? -21.77652 51.00783 4.54123   1.000 53.49743  ? 67  SER B OG  1 
ATOM   5392 N N   . GLY D 2 70  ? -19.82674 48.87823 5.48401   1.000 48.21860  ? 68  GLY B N   1 
ATOM   5393 C CA  . GLY D 2 70  ? -19.85479 47.45024 5.73188   1.000 44.85754  ? 68  GLY B CA  1 
ATOM   5394 C C   . GLY D 2 70  ? -18.51421 46.87165 6.13220   1.000 47.92810  ? 68  GLY B C   1 
ATOM   5395 O O   . GLY D 2 70  ? -18.08999 46.99113 7.28585   1.000 47.39258  ? 68  GLY B O   1 
ATOM   5396 N N   . THR D 2 71  ? -17.83724 46.23756 5.17788   1.000 42.60854  ? 69  THR B N   1 
ATOM   5397 C CA  . THR D 2 71  ? -16.51932 45.66290 5.40754   1.000 46.98500  ? 69  THR B CA  1 
ATOM   5398 C C   . THR D 2 71  ? -15.46100 46.22765 4.46425   1.000 46.99248  ? 69  THR B C   1 
ATOM   5399 O O   . THR D 2 71  ? -14.33269 45.72061 4.44647   1.000 47.40590  ? 69  THR B O   1 
ATOM   5400 C CB  . THR D 2 71  ? -16.58324 44.13429 5.28142   1.000 53.10990  ? 69  THR B CB  1 
ATOM   5401 O OG1 . THR D 2 71  ? -17.07979 43.77776 3.98384   1.000 47.59325  ? 69  THR B OG1 1 
ATOM   5402 C CG2 . THR D 2 71  ? -17.51097 43.54436 6.34687   1.000 45.76629  ? 69  THR B CG2 1 
ATOM   5403 N N   . ASP D 2 72  ? -15.78432 47.26889 3.69235   1.000 39.40962  ? 70  ASP B N   1 
ATOM   5404 C CA  . ASP D 2 72  ? -14.88162 47.82285 2.68491   1.000 49.49558  ? 70  ASP B CA  1 
ATOM   5405 C C   . ASP D 2 72  ? -14.71511 49.31954 2.91061   1.000 50.54828  ? 70  ASP B C   1 
ATOM   5406 O O   . ASP D 2 72  ? -15.69445 50.07142 2.84774   1.000 44.12004  ? 70  ASP B O   1 
ATOM   5407 C CB  . ASP D 2 72  ? -15.41137 47.55421 1.27295   1.000 48.78249  ? 70  ASP B CB  1 
ATOM   5408 C CG  . ASP D 2 72  ? -15.48877 46.07328 0.95517   1.000 55.97366  ? 70  ASP B CG  1 
ATOM   5409 O OD1 . ASP D 2 72  ? -14.46278 45.37551 1.10600   1.000 66.79269  ? 70  ASP B OD1 1 
ATOM   5410 O OD2 . ASP D 2 72  ? -16.58010 45.60353 0.57045   1.000 56.62508  ? 70  ASP B OD2 1 
ATOM   5411 N N   . PHE D 2 73  ? -13.47692 49.75321 3.15046   1.000 41.99505  ? 71  PHE B N   1 
ATOM   5412 C CA  . PHE D 2 73  ? -13.18247 51.15801 3.39261   1.000 41.91099  ? 71  PHE B CA  1 
ATOM   5413 C C   . PHE D 2 73  ? -11.94933 51.55757 2.59420   1.000 41.76859  ? 71  PHE B C   1 
ATOM   5414 O O   . PHE D 2 73  ? -11.08692 50.72374 2.30405   1.000 42.65353  ? 71  PHE B O   1 
ATOM   5415 C CB  . PHE D 2 73  ? -12.98687 51.41702 4.89192   1.000 38.63689  ? 71  PHE B CB  1 
ATOM   5416 C CG  . PHE D 2 73  ? -14.06850 50.81413 5.74518   1.000 35.79748  ? 71  PHE B CG  1 
ATOM   5417 C CD1 . PHE D 2 73  ? -15.26137 51.48767 5.95144   1.000 38.10232  ? 71  PHE B CD1 1 
ATOM   5418 C CD2 . PHE D 2 73  ? -13.90115 49.56459 6.31995   1.000 37.65117  ? 71  PHE B CD2 1 
ATOM   5419 C CE1 . PHE D 2 73  ? -16.26053 50.93273 6.73131   1.000 42.49936  ? 71  PHE B CE1 1 
ATOM   5420 C CE2 . PHE D 2 73  ? -14.89367 49.00013 7.09560   1.000 36.40569  ? 71  PHE B CE2 1 
ATOM   5421 C CZ  . PHE D 2 73  ? -16.07551 49.68330 7.30434   1.000 50.87060  ? 71  PHE B CZ  1 
ATOM   5422 N N   . THR D 2 74  ? -11.86892 52.84316 2.23988   1.000 32.45612  ? 72  THR B N   1 
ATOM   5423 C CA  . THR D 2 74  ? -10.83880 53.32649 1.32756   1.000 32.55071  ? 72  THR B CA  1 
ATOM   5424 C C   . THR D 2 74  ? -10.34144 54.69877 1.75797   1.000 37.86729  ? 72  THR B C   1 
ATOM   5425 O O   . THR D 2 74  ? -11.13382 55.56284 2.14195   1.000 40.04791  ? 72  THR B O   1 
ATOM   5426 C CB  . THR D 2 74  ? -11.36900 53.41097 -0.11248  1.000 44.69294  ? 72  THR B CB  1 
ATOM   5427 O OG1 . THR D 2 74  ? -11.85434 52.12517 -0.52269  1.000 50.10056  ? 72  THR B OG1 1 
ATOM   5428 C CG2 . THR D 2 74  ? -10.27147 53.87367 -1.07651  1.000 45.69534  ? 72  THR B CG2 1 
ATOM   5429 N N   . LEU D 2 75  ? -9.02810  54.89476 1.68009   1.000 42.58559  ? 73  LEU B N   1 
ATOM   5430 C CA  . LEU D 2 75  ? -8.39729  56.18325 1.93416   1.000 41.55557  ? 73  LEU B CA  1 
ATOM   5431 C C   . LEU D 2 75  ? -7.82991  56.73295 0.63436   1.000 43.13430  ? 73  LEU B C   1 
ATOM   5432 O O   . LEU D 2 75  ? -7.09948  56.03266 -0.07306  1.000 38.98673  ? 73  LEU B O   1 
ATOM   5433 C CB  . LEU D 2 75  ? -7.28535  56.05884 2.97585   1.000 37.66633  ? 73  LEU B CB  1 
ATOM   5434 C CG  . LEU D 2 75  ? -6.46601  57.33205 3.19789   1.000 35.04554  ? 73  LEU B CG  1 
ATOM   5435 C CD1 . LEU D 2 75  ? -7.31858  58.44929 3.78439   1.000 36.44580  ? 73  LEU B CD1 1 
ATOM   5436 C CD2 . LEU D 2 75  ? -5.26641  57.04148 4.07909   1.000 34.88510  ? 73  LEU B CD2 1 
ATOM   5437 N N   . THR D 2 76  ? -8.14406  57.98955 0.33227   1.000 45.98146  ? 74  THR B N   1 
ATOM   5438 C CA  . THR D 2 76  ? -7.75778  58.60442 -0.93321  1.000 49.34377  ? 74  THR B CA  1 
ATOM   5439 C C   . THR D 2 76  ? -6.91239  59.84357 -0.67203  1.000 50.25930  ? 74  THR B C   1 
ATOM   5440 O O   . THR D 2 76  ? -7.33656  60.74718 0.05861   1.000 47.88450  ? 74  THR B O   1 
ATOM   5441 C CB  . THR D 2 76  ? -8.99025  58.96772 -1.76583  1.000 49.06070  ? 74  THR B CB  1 
ATOM   5442 O OG1 . THR D 2 76  ? -9.75516  57.78275 -2.03183  1.000 46.17781  ? 74  THR B OG1 1 
ATOM   5443 C CG2 . THR D 2 76  ? -8.56766  59.60255 -3.08212  1.000 42.23155  ? 74  THR B CG2 1 
ATOM   5444 N N   . ILE D 2 77  ? -5.71716  59.87290 -1.25937  1.000 43.41482  ? 75  ILE B N   1 
ATOM   5445 C CA  . ILE D 2 77  ? -4.87309  61.06062 -1.32408  1.000 47.17706  ? 75  ILE B CA  1 
ATOM   5446 C C   . ILE D 2 77  ? -4.94782  61.56197 -2.76118  1.000 57.21083  ? 75  ILE B C   1 
ATOM   5447 O O   . ILE D 2 77  ? -4.35171  60.96157 -3.66451  1.000 52.51937  ? 75  ILE B O   1 
ATOM   5448 C CB  . ILE D 2 77  ? -3.42269  60.76371 -0.91674  1.000 47.45203  ? 75  ILE B CB  1 
ATOM   5449 C CG1 . ILE D 2 77  ? -3.36887  60.06100 0.43751   1.000 40.28905  ? 75  ILE B CG1 1 
ATOM   5450 C CG2 . ILE D 2 77  ? -2.59696  62.04621 -0.87733  1.000 49.56752  ? 75  ILE B CG2 1 
ATOM   5451 C CD1 . ILE D 2 77  ? -1.98359  59.59185 0.81104   1.000 41.87936  ? 75  ILE B CD1 1 
ATOM   5452 N N   . SER D 2 78  ? -5.67908  62.66094 -2.98078  1.000 54.24511  ? 76  SER B N   1 
ATOM   5453 C CA  . SER D 2 78  ? -5.95278  63.10787 -4.34627  1.000 55.44878  ? 76  SER B CA  1 
ATOM   5454 C C   . SER D 2 78  ? -4.71526  63.67644 -5.04129  1.000 59.17282  ? 76  SER B C   1 
ATOM   5455 O O   . SER D 2 78  ? -4.62219  63.60033 -6.27286  1.000 59.47592  ? 76  SER B O   1 
ATOM   5456 C CB  . SER D 2 78  ? -7.07927  64.14055 -4.34686  1.000 53.79481  ? 76  SER B CB  1 
ATOM   5457 O OG  . SER D 2 78  ? -6.69656  65.30262 -3.63103  1.000 62.67245  ? 76  SER B OG  1 
ATOM   5458 N N   . SER D 2 79  ? -3.75763  64.24609 -4.29090  1.000 51.39106  ? 77  SER B N   1 
ATOM   5459 C CA  . SER D 2 79  ? -2.55948  64.82731 -4.91347  1.000 51.64203  ? 77  SER B CA  1 
ATOM   5460 C C   . SER D 2 79  ? -1.37327  64.67460 -3.95619  1.000 54.47663  ? 77  SER B C   1 
ATOM   5461 O O   . SER D 2 79  ? -1.11892  65.54124 -3.11863  1.000 58.72493  ? 77  SER B O   1 
ATOM   5462 C CB  . SER D 2 79  ? -2.78075  66.28349 -5.28815  1.000 57.29397  ? 77  SER B CB  1 
ATOM   5463 O OG  . SER D 2 79  ? -1.61424  66.81879 -5.88738  1.000 62.10472  ? 77  SER B OG  1 
ATOM   5464 N N   . LEU D 2 80  ? -0.62195  63.59298 -4.13888  1.000 51.36558  ? 78  LEU B N   1 
ATOM   5465 C CA  . LEU D 2 80  ? 0.45553   63.23474 -3.22511  1.000 53.28787  ? 78  LEU B CA  1 
ATOM   5466 C C   . LEU D 2 80  ? 1.52248   64.32421 -3.15344  1.000 58.25115  ? 78  LEU B C   1 
ATOM   5467 O O   . LEU D 2 80  ? 1.78624   65.03583 -4.12747  1.000 55.26176  ? 78  LEU B O   1 
ATOM   5468 C CB  . LEU D 2 80  ? 1.09295   61.91747 -3.66609  1.000 50.12477  ? 78  LEU B CB  1 
ATOM   5469 C CG  . LEU D 2 80  ? 1.96503   61.19117 -2.64984  1.000 54.91103  ? 78  LEU B CG  1 
ATOM   5470 C CD1 . LEU D 2 80  ? 1.15455   60.87369 -1.39707  1.000 50.76530  ? 78  LEU B CD1 1 
ATOM   5471 C CD2 . LEU D 2 80  ? 2.52944   59.92980 -3.27111  1.000 51.07570  ? 78  LEU B CD2 1 
ATOM   5472 N N   . GLN D 2 81  ? 2.15317   64.43052 -1.98758  1.000 52.26016  ? 79  GLN B N   1 
ATOM   5473 C CA  . GLN D 2 81  ? 3.14888   65.44469 -1.67957  1.000 52.01320  ? 79  GLN B CA  1 
ATOM   5474 C C   . GLN D 2 81  ? 4.37511   64.80464 -1.04790  1.000 54.87872  ? 79  GLN B C   1 
ATOM   5475 O O   . GLN D 2 81  ? 4.30411   63.68426 -0.52909  1.000 50.61273  ? 79  GLN B O   1 
ATOM   5476 C CB  . GLN D 2 81  ? 2.56707   66.50875 -0.73800  1.000 46.23738  ? 79  GLN B CB  1 
ATOM   5477 C CG  . GLN D 2 81  ? 1.32523   67.19307 -1.28007  1.000 53.99162  ? 79  GLN B CG  1 
ATOM   5478 C CD  . GLN D 2 81  ? 1.60246   68.02083 -2.52391  1.000 65.33581  ? 79  GLN B CD  1 
ATOM   5479 O OE1 . GLN D 2 81  ? 2.75676   68.24766 -2.89278  1.000 63.47234  ? 79  GLN B OE1 1 
ATOM   5480 N NE2 . GLN D 2 81  ? 0.53956   68.47982 -3.17543  1.000 62.29588  ? 79  GLN B NE2 1 
ATOM   5481 N N   . PRO D 2 82  ? 5.52760   65.48627 -1.09037  1.000 58.38284  ? 80  PRO B N   1 
ATOM   5482 C CA  . PRO D 2 82  ? 6.75170   64.88395 -0.52727  1.000 57.02153  ? 80  PRO B CA  1 
ATOM   5483 C C   . PRO D 2 82  ? 6.65910   64.58282 0.95876   1.000 59.97804  ? 80  PRO B C   1 
ATOM   5484 O O   . PRO D 2 82  ? 7.33473   63.66055 1.43599   1.000 56.32846  ? 80  PRO B O   1 
ATOM   5485 C CB  . PRO D 2 82  ? 7.82935   65.94169 -0.81359  1.000 54.25342  ? 80  PRO B CB  1 
ATOM   5486 C CG  . PRO D 2 82  ? 7.29101   66.73841 -1.94546  1.000 61.38942  ? 80  PRO B CG  1 
ATOM   5487 C CD  . PRO D 2 82  ? 5.80404   66.76979 -1.76030  1.000 58.39528  ? 80  PRO B CD  1 
ATOM   5488 N N   . GLU D 2 83  ? 5.84488   65.32986 1.70599   1.000 50.50287  ? 81  GLU B N   1 
ATOM   5489 C CA  . GLU D 2 83  ? 5.76631   65.15160 3.14928   1.000 58.11934  ? 81  GLU B CA  1 
ATOM   5490 C C   . GLU D 2 83  ? 4.89312   63.97053 3.55086   1.000 65.86865  ? 81  GLU B C   1 
ATOM   5491 O O   . GLU D 2 83  ? 4.75740   63.70185 4.75030   1.000 61.57077  ? 81  GLU B O   1 
ATOM   5492 C CB  . GLU D 2 83  ? 5.25591   66.43640 3.81858   1.000 55.37587  ? 81  GLU B CB  1 
ATOM   5493 C CG  . GLU D 2 83  ? 3.87920   66.91477 3.37040   1.000 45.34679  ? 81  GLU B CG  1 
ATOM   5494 C CD  . GLU D 2 83  ? 3.93398   67.80238 2.12858   1.000 60.83562  ? 81  GLU B CD  1 
ATOM   5495 O OE1 . GLU D 2 83  ? 4.85432   67.60326 1.30328   1.000 61.22169  ? 81  GLU B OE1 1 
ATOM   5496 O OE2 . GLU D 2 83  ? 3.06010   68.69702 1.97494   1.000 48.21486  ? 81  GLU B OE2 1 
ATOM   5497 N N   . ASP D 2 84  ? 4.32019   63.24945 2.58735   1.000 59.65189  ? 82  ASP B N   1 
ATOM   5498 C CA  . ASP D 2 84  ? 3.44457   62.12417 2.87998   1.000 52.24735  ? 82  ASP B CA  1 
ATOM   5499 C C   . ASP D 2 84  ? 4.18943   60.79852 2.98741   1.000 58.91721  ? 82  ASP B C   1 
ATOM   5500 O O   . ASP D 2 84  ? 3.55009   59.76192 3.20819   1.000 46.22800  ? 82  ASP B O   1 
ATOM   5501 C CB  . ASP D 2 84  ? 2.35030   62.03589 1.81996   1.000 49.28432  ? 82  ASP B CB  1 
ATOM   5502 C CG  . ASP D 2 84  ? 1.56812   63.32863 1.69704   1.000 55.20211  ? 82  ASP B CG  1 
ATOM   5503 O OD1 . ASP D 2 84  ? 1.79104   64.22652 2.54016   1.000 43.66921  ? 82  ASP B OD1 1 
ATOM   5504 O OD2 . ASP D 2 84  ? 0.74289   63.45193 0.76427   1.000 47.97161  ? 82  ASP B OD2 1 
ATOM   5505 N N   . PHE D 2 85  ? 5.51713   60.80327 2.84475   1.000 58.50213  ? 83  PHE B N   1 
ATOM   5506 C CA  . PHE D 2 85  ? 6.29960   59.60155 3.11555   1.000 52.93071  ? 83  PHE B CA  1 
ATOM   5507 C C   . PHE D 2 85  ? 5.98233   59.10519 4.51685   1.000 59.98363  ? 83  PHE B C   1 
ATOM   5508 O O   . PHE D 2 85  ? 6.47381   59.65376 5.51018   1.000 50.86396  ? 83  PHE B O   1 
ATOM   5509 C CB  . PHE D 2 85  ? 7.80120   59.85605 2.97298   1.000 56.20815  ? 83  PHE B CB  1 
ATOM   5510 C CG  . PHE D 2 85  ? 8.65500   58.68673 3.39537   1.000 51.19212  ? 83  PHE B CG  1 
ATOM   5511 C CD1 . PHE D 2 85  ? 8.79245   57.57726 2.57156   1.000 56.23421  ? 83  PHE B CD1 1 
ATOM   5512 C CD2 . PHE D 2 85  ? 9.32229   58.69723 4.61530   1.000 51.50802  ? 83  PHE B CD2 1 
ATOM   5513 C CE1 . PHE D 2 85  ? 9.57876   56.49445 2.95363   1.000 58.07667  ? 83  PHE B CE1 1 
ATOM   5514 C CE2 . PHE D 2 85  ? 10.11113  57.61768 5.00594   1.000 54.81485  ? 83  PHE B CE2 1 
ATOM   5515 C CZ  . PHE D 2 85  ? 10.24219  56.51531 4.17421   1.000 47.52446  ? 83  PHE B CZ  1 
ATOM   5516 N N   . ALA D 2 86  ? 5.15463   58.07191 4.60007   1.000 53.79978  ? 84  ALA B N   1 
ATOM   5517 C CA  . ALA D 2 86  ? 4.63086   57.62821 5.87800   1.000 50.58476  ? 84  ALA B CA  1 
ATOM   5518 C C   . ALA D 2 86  ? 4.00966   56.25926 5.68151   1.000 49.15328  ? 84  ALA B C   1 
ATOM   5519 O O   . ALA D 2 86  ? 3.75250   55.83325 4.55071   1.000 46.23016  ? 84  ALA B O   1 
ATOM   5520 C CB  . ALA D 2 86  ? 3.59591   58.61573 6.42872   1.000 44.59388  ? 84  ALA B CB  1 
ATOM   5521 N N   . THR D 2 87  ? 3.78289   55.57241 6.79527   1.000 39.54652  ? 85  THR B N   1 
ATOM   5522 C CA  . THR D 2 87  ? 2.94900   54.37869 6.81150   1.000 39.57988  ? 85  THR B CA  1 
ATOM   5523 C C   . THR D 2 87  ? 1.55658   54.77055 7.30475   1.000 45.45702  ? 85  THR B C   1 
ATOM   5524 O O   . THR D 2 87  ? 1.42690   55.51265 8.28733   1.000 39.14596  ? 85  THR B O   1 
ATOM   5525 C CB  . THR D 2 87  ? 3.56386   53.28631 7.68757   1.000 41.30220  ? 85  THR B CB  1 
ATOM   5526 O OG1 . THR D 2 87  ? 4.93887   53.09048 7.31988   1.000 42.69280  ? 85  THR B OG1 1 
ATOM   5527 C CG2 . THR D 2 87  ? 2.81491   51.97367 7.49992   1.000 38.95478  ? 85  THR B CG2 1 
ATOM   5528 N N   . TYR D 2 88  ? 0.52373   54.30822 6.59648   1.000 39.38280  ? 86  TYR B N   1 
ATOM   5529 C CA  . TYR D 2 88  ? -0.86664  54.62516 6.90302   1.000 32.78598  ? 86  TYR B CA  1 
ATOM   5530 C C   . TYR D 2 88  ? -1.56248  53.38897 7.45996   1.000 31.95606  ? 86  TYR B C   1 
ATOM   5531 O O   . TYR D 2 88  ? -1.32135  52.27269 6.99561   1.000 29.21416  ? 86  TYR B O   1 
ATOM   5532 C CB  . TYR D 2 88  ? -1.59878  55.13927 5.65226   1.000 39.56555  ? 86  TYR B CB  1 
ATOM   5533 C CG  . TYR D 2 88  ? -1.02806  56.44230 5.11862   1.000 41.79587  ? 86  TYR B CG  1 
ATOM   5534 C CD1 . TYR D 2 88  ? 0.13451   56.45449 4.35663   1.000 37.83512  ? 86  TYR B CD1 1 
ATOM   5535 C CD2 . TYR D 2 88  ? -1.64222  57.66005 5.39939   1.000 44.33259  ? 86  TYR B CD2 1 
ATOM   5536 C CE1 . TYR D 2 88  ? 0.67381   57.64462 3.88482   1.000 38.14314  ? 86  TYR B CE1 1 
ATOM   5537 C CE2 . TYR D 2 88  ? -1.11382  58.85543 4.93153   1.000 48.79300  ? 86  TYR B CE2 1 
ATOM   5538 C CZ  . TYR D 2 88  ? 0.04483   58.83889 4.17441   1.000 46.17136  ? 86  TYR B CZ  1 
ATOM   5539 O OH  . TYR D 2 88  ? 0.57527   60.01926 3.70596   1.000 55.44617  ? 86  TYR B OH  1 
ATOM   5540 N N   . TYR D 2 89  ? -2.41588  53.58383 8.46634   1.000 28.71861  ? 87  TYR B N   1 
ATOM   5541 C CA  . TYR D 2 89  ? -3.10804  52.47967 9.11981   1.000 31.96386  ? 87  TYR B CA  1 
ATOM   5542 C C   . TYR D 2 89  ? -4.60445  52.76094 9.16357   1.000 35.17708  ? 87  TYR B C   1 
ATOM   5543 O O   . TYR D 2 89  ? -5.01659  53.85816 9.55902   1.000 29.71565  ? 87  TYR B O   1 
ATOM   5544 C CB  . TYR D 2 89  ? -2.58422  52.25740 10.55081  1.000 28.96171  ? 87  TYR B CB  1 
ATOM   5545 C CG  . TYR D 2 89  ? -1.10958  51.89036 10.66028  1.000 35.90426  ? 87  TYR B CG  1 
ATOM   5546 C CD1 . TYR D 2 89  ? -0.13071  52.86969 10.80624  1.000 28.72074  ? 87  TYR B CD1 1 
ATOM   5547 C CD2 . TYR D 2 89  ? -0.70210  50.56287 10.64347  1.000 28.24978  ? 87  TYR B CD2 1 
ATOM   5548 C CE1 . TYR D 2 89  ? 1.21899   52.52628 10.92276  1.000 30.03674  ? 87  TYR B CE1 1 
ATOM   5549 C CE2 . TYR D 2 89  ? 0.63651   50.21560 10.75495  1.000 30.41981  ? 87  TYR B CE2 1 
ATOM   5550 C CZ  . TYR D 2 89  ? 1.58882   51.20303 10.89339  1.000 32.44107  ? 87  TYR B CZ  1 
ATOM   5551 O OH  . TYR D 2 89  ? 2.91340   50.85235 11.00428  1.000 33.94058  ? 87  TYR B OH  1 
ATOM   5552 N N   . CYS D 2 90  ? -5.41569  51.77977 8.75224   1.000 35.43589  ? 88  CYS B N   1 
ATOM   5553 C CA  . CYS D 2 90  ? -6.81890  51.78057 9.15090   1.000 28.87864  ? 88  CYS B CA  1 
ATOM   5554 C C   . CYS D 2 90  ? -6.95508  51.15343 10.53094  1.000 32.90699  ? 88  CYS B C   1 
ATOM   5555 O O   . CYS D 2 90  ? -6.14098  50.32385 10.94563  1.000 34.78224  ? 88  CYS B O   1 
ATOM   5556 C CB  . CYS D 2 90  ? -7.70468  51.02205 8.15400   1.000 37.37264  ? 88  CYS B CB  1 
ATOM   5557 S SG  . CYS D 2 90  ? -7.21933  49.29266 7.88970   1.000 50.75274  ? 88  CYS B SG  1 
ATOM   5558 N N   . VAL D 2 91  ? -7.98685  51.57611 11.25318  1.000 30.45473  ? 89  VAL B N   1 
ATOM   5559 C CA  . VAL D 2 91  ? -8.31156  50.99626 12.54706  1.000 36.56849  ? 89  VAL B CA  1 
ATOM   5560 C C   . VAL D 2 91  ? -9.83097  50.94830 12.66277  1.000 42.86189  ? 89  VAL B C   1 
ATOM   5561 O O   . VAL D 2 91  ? -10.51628 51.94127 12.38606  1.000 36.58370  ? 89  VAL B O   1 
ATOM   5562 C CB  . VAL D 2 91  ? -7.65817  51.77616 13.71196  1.000 35.54227  ? 89  VAL B CB  1 
ATOM   5563 C CG1 . VAL D 2 91  ? -8.20767  53.20623 13.82940  1.000 32.16550  ? 89  VAL B CG1 1 
ATOM   5564 C CG2 . VAL D 2 91  ? -7.80040  51.01332 15.03326  1.000 28.74834  ? 89  VAL B CG2 1 
ATOM   5565 N N   . GLY D 2 92  ? -10.35730 49.77425 13.01272  1.000 33.70501  ? 90  GLY B N   1 
ATOM   5566 C CA  . GLY D 2 92  ? -11.78721 49.57859 13.14409  1.000 37.43721  ? 90  GLY B CA  1 
ATOM   5567 C C   . GLY D 2 92  ? -12.17937 49.26767 14.57263  1.000 41.03452  ? 90  GLY B C   1 
ATOM   5568 O O   . GLY D 2 92  ? -11.35832 48.76252 15.34644  1.000 39.98057  ? 90  GLY B O   1 
ATOM   5569 N N   . HIS D 2 93  ? -13.42657 49.57184 14.93506  1.000 36.30111  ? 91  HIS B N   1 
ATOM   5570 C CA  . HIS D 2 93  ? -13.96608 49.31730 16.26722  1.000 39.31229  ? 91  HIS B CA  1 
ATOM   5571 C C   . HIS D 2 93  ? -15.13875 48.35287 16.14043  1.000 40.90272  ? 91  HIS B C   1 
ATOM   5572 O O   . HIS D 2 93  ? -15.96851 48.49911 15.23565  1.000 37.50599  ? 91  HIS B O   1 
ATOM   5573 C CB  . HIS D 2 93  ? -14.40313 50.63219 16.93191  1.000 37.79167  ? 91  HIS B CB  1 
ATOM   5574 C CG  . HIS D 2 93  ? -14.83658 50.48384 18.35855  1.000 39.80139  ? 91  HIS B CG  1 
ATOM   5575 N ND1 . HIS D 2 93  ? -14.03313 49.91999 19.32749  1.000 37.26401  ? 91  HIS B ND1 1 
ATOM   5576 C CD2 . HIS D 2 93  ? -15.98168 50.84929 18.98441  1.000 42.56409  ? 91  HIS B CD2 1 
ATOM   5577 C CE1 . HIS D 2 93  ? -14.66985 49.93467 20.48654  1.000 41.38730  ? 91  HIS B CE1 1 
ATOM   5578 N NE2 . HIS D 2 93  ? -15.85446 50.49381 20.30604  1.000 41.20295  ? 91  HIS B NE2 1 
ATOM   5579 N N   . TYR D 2 94  ? -15.20159 47.36221 17.03731  1.000 37.98555  ? 92  TYR B N   1 
ATOM   5580 C CA  . TYR D 2 94  ? -16.10086 46.22325 16.88016  1.000 38.71379  ? 92  TYR B CA  1 
ATOM   5581 C C   . TYR D 2 94  ? -16.73660 45.85005 18.20911  1.000 40.96727  ? 92  TYR B C   1 
ATOM   5582 O O   . TYR D 2 94  ? -16.26251 46.23444 19.27954  1.000 41.51206  ? 92  TYR B O   1 
ATOM   5583 C CB  . TYR D 2 94  ? -15.37262 44.98566 16.34879  1.000 38.29584  ? 92  TYR B CB  1 
ATOM   5584 C CG  . TYR D 2 94  ? -14.59907 45.21679 15.09040  1.000 45.73764  ? 92  TYR B CG  1 
ATOM   5585 C CD1 . TYR D 2 94  ? -13.32281 45.76715 15.12844  1.000 46.08677  ? 92  TYR B CD1 1 
ATOM   5586 C CD2 . TYR D 2 94  ? -15.13706 44.87534 13.85682  1.000 51.07971  ? 92  TYR B CD2 1 
ATOM   5587 C CE1 . TYR D 2 94  ? -12.60440 45.98053 13.96805  1.000 52.44291  ? 92  TYR B CE1 1 
ATOM   5588 C CE2 . TYR D 2 94  ? -14.43399 45.08752 12.69153  1.000 51.72989  ? 92  TYR B CE2 1 
ATOM   5589 C CZ  . TYR D 2 94  ? -13.16500 45.63843 12.75193  1.000 55.73981  ? 92  TYR B CZ  1 
ATOM   5590 O OH  . TYR D 2 94  ? -12.45953 45.84544 11.59061  1.000 57.02009  ? 92  TYR B OH  1 
ATOM   5591 N N   . GLY D 2 95  ? -17.81396 45.05603 18.12706  1.000 39.52115  ? 93  GLY B N   1 
ATOM   5592 C CA  . GLY D 2 95  ? -18.37196 44.38022 19.27604  1.000 49.13998  ? 93  GLY B CA  1 
ATOM   5593 C C   . GLY D 2 95  ? -19.86886 44.58307 19.38166  1.000 54.76609  ? 93  GLY B C   1 
ATOM   5594 O O   . GLY D 2 95  ? -20.54119 44.95451 18.41254  1.000 41.70490  ? 93  GLY B O   1 
ATOM   5595 N N   . SER D 2 96  ? -20.38266 44.32410 20.58050  1.000 51.06403  ? 94  SER B N   1 
ATOM   5596 C CA  . SER D 2 96  ? -21.78242 44.49137 20.94272  1.000 58.07146  ? 94  SER B CA  1 
ATOM   5597 C C   . SER D 2 96  ? -21.89680 45.55142 22.04374  1.000 61.96853  ? 94  SER B C   1 
ATOM   5598 O O   . SER D 2 96  ? -20.94643 46.28381 22.33665  1.000 53.36198  ? 94  SER B O   1 
ATOM   5599 C CB  . SER D 2 96  ? -22.37215 43.15484 21.39226  1.000 55.91269  ? 94  SER B CB  1 
ATOM   5600 O OG  . SER D 2 96  ? -21.75050 42.71591 22.58937  1.000 57.83972  ? 94  SER B OG  1 
ATOM   5601 N N   . GLU D 2 97  ? -23.07465 45.62994 22.66777  1.000 59.66663  ? 95  GLU B N   1 
ATOM   5602 C CA  . GLU D 2 97  ? -23.22026 46.52604 23.80926  1.000 63.20127  ? 95  GLU B CA  1 
ATOM   5603 C C   . GLU D 2 97  ? -22.49659 46.01137 25.04581  1.000 60.87613  ? 95  GLU B C   1 
ATOM   5604 O O   . GLU D 2 97  ? -22.31728 46.77531 26.00083  1.000 56.12527  ? 95  GLU B O   1 
ATOM   5605 C CB  . GLU D 2 97  ? -24.70018 46.76796 24.13150  1.000 72.12350  ? 95  GLU B CB  1 
ATOM   5606 C CG  . GLU D 2 97  ? -25.62403 45.56672 23.95433  1.000 75.54425  ? 95  GLU B CG  1 
ATOM   5607 C CD  . GLU D 2 97  ? -26.15374 45.44101 22.53388  1.000 80.96087  ? 95  GLU B CD  1 
ATOM   5608 O OE1 . GLU D 2 97  ? -25.45095 44.84363 21.68927  1.000 74.17863  ? 95  GLU B OE1 1 
ATOM   5609 O OE2 . GLU D 2 97  ? -27.26454 45.95156 22.26001  1.000 84.59633  ? 95  GLU B OE2 1 
ATOM   5610 N N   . ASN D 2 98  A -22.06903 44.74656 25.04515  1.000 57.17273  ? 95  ASN B N   1 
ATOM   5611 C CA  . ASN D 2 98  A -21.28372 44.17935 26.13497  1.000 62.36762  ? 95  ASN B CA  1 
ATOM   5612 C C   . ASN D 2 98  A -19.96138 43.60516 25.64071  1.000 62.75666  ? 95  ASN B C   1 
ATOM   5613 O O   . ASN D 2 98  A -19.37617 42.73810 26.29902  1.000 54.90530  ? 95  ASN B O   1 
ATOM   5614 C CB  . ASN D 2 98  A -22.09458 43.11652 26.87312  1.000 65.25543  ? 95  ASN B CB  1 
ATOM   5615 C CG  . ASN D 2 98  A -23.34483 43.68881 27.50639  1.000 71.85206  ? 95  ASN B CG  1 
ATOM   5616 O OD1 . ASN D 2 98  A -23.29777 44.23039 28.61715  1.000 67.80606  ? 95  ASN B OD1 1 
ATOM   5617 N ND2 . ASN D 2 98  A -24.47571 43.57672 26.80342  1.000 59.18003  ? 95  ASN B ND2 1 
ATOM   5618 N N   . ASP D 2 99  B -19.48393 44.08532 24.49345  1.000 61.96293  ? 95  ASP B N   1 
ATOM   5619 C CA  . ASP D 2 99  B -18.21558 43.68041 23.90576  1.000 60.32557  ? 95  ASP B CA  1 
ATOM   5620 C C   . ASP D 2 99  B -17.61535 44.88330 23.19362  1.000 51.38614  ? 95  ASP B C   1 
ATOM   5621 O O   . ASP D 2 99  B -18.33887 45.62928 22.53366  1.000 53.57447  ? 95  ASP B O   1 
ATOM   5622 C CB  . ASP D 2 99  B -18.40560 42.52305 22.91805  1.000 56.56583  ? 95  ASP B CB  1 
ATOM   5623 C CG  . ASP D 2 99  B -17.80754 41.24296 23.41936  1.000 54.22627  ? 95  ASP B CG  1 
ATOM   5624 O OD1 . ASP D 2 99  B -17.27322 41.25646 24.54696  1.000 61.85276  ? 95  ASP B OD1 1 
ATOM   5625 O OD2 . ASP D 2 99  B -17.86120 40.22822 22.69238  1.000 70.28184  ? 95  ASP B OD2 1 
ATOM   5626 N N   . ALA D 2 100 C -16.30113 45.07311 23.32091  1.000 46.50954  ? 95  ALA B N   1 
ATOM   5627 C CA  . ALA D 2 100 C -15.65492 46.18326 22.62709  1.000 48.89595  ? 95  ALA B CA  1 
ATOM   5628 C C   . ALA D 2 100 C -14.24009 45.79788 22.22704  1.000 46.30023  ? 95  ALA B C   1 
ATOM   5629 O O   . ALA D 2 100 C -13.44141 45.40579 23.08157  1.000 43.94372  ? 95  ALA B O   1 
ATOM   5630 C CB  . ALA D 2 100 C -15.63192 47.44721 23.49551  1.000 47.85362  ? 95  ALA B CB  1 
ATOM   5631 N N   . TYR D 2 101 D -13.93110 45.94358 20.93621  1.000 46.91131  ? 95  TYR B N   1 
ATOM   5632 C CA  . TYR D 2 101 D -12.62234 45.60181 20.39474  1.000 47.34807  ? 95  TYR B CA  1 
ATOM   5633 C C   . TYR D 2 101 D -12.19226 46.62654 19.34833  1.000 42.05647  ? 95  TYR B C   1 
ATOM   5634 O O   . TYR D 2 101 D -13.01120 47.36672 18.78905  1.000 37.49687  ? 95  TYR B O   1 
ATOM   5635 C CB  . TYR D 2 101 D -12.62533 44.19943 19.77415  1.000 35.08960  ? 95  TYR B CB  1 
ATOM   5636 C CG  . TYR D 2 101 D -13.18013 43.14816 20.70002  1.000 44.58373  ? 95  TYR B CG  1 
ATOM   5637 C CD1 . TYR D 2 101 D -12.38834 42.57856 21.68675  1.000 45.47676  ? 95  TYR B CD1 1 
ATOM   5638 C CD2 . TYR D 2 101 D -14.50105 42.73090 20.59197  1.000 46.56915  ? 95  TYR B CD2 1 
ATOM   5639 C CE1 . TYR D 2 101 D -12.89758 41.61186 22.54419  1.000 59.03920  ? 95  TYR B CE1 1 
ATOM   5640 C CE2 . TYR D 2 101 D -15.02080 41.77028 21.43493  1.000 54.56067  ? 95  TYR B CE2 1 
ATOM   5641 C CZ  . TYR D 2 101 D -14.21772 41.20999 22.41345  1.000 63.79749  ? 95  TYR B CZ  1 
ATOM   5642 O OH  . TYR D 2 101 D -14.73383 40.24688 23.25769  1.000 55.17856  ? 95  TYR B OH  1 
ATOM   5643 N N   . TYR D 2 102 ? -10.87939 46.66286 19.10572  1.000 31.69552  ? 96  TYR B N   1 
ATOM   5644 C CA  . TYR D 2 102 ? -10.28157 47.39402 17.99786  1.000 38.09494  ? 96  TYR B CA  1 
ATOM   5645 C C   . TYR D 2 102 ? -9.30451  46.49148 17.26331  1.000 34.13166  ? 96  TYR B C   1 
ATOM   5646 O O   . TYR D 2 102 ? -8.77520  45.52901 17.82477  1.000 32.62510  ? 96  TYR B O   1 
ATOM   5647 C CB  . TYR D 2 102 ? -9.51077  48.62949 18.44065  1.000 28.79263  ? 96  TYR B CB  1 
ATOM   5648 C CG  . TYR D 2 102 ? -10.32057 49.74625 19.01207  1.000 31.26411  ? 96  TYR B CG  1 
ATOM   5649 C CD1 . TYR D 2 102 ? -10.63651 49.76631 20.36110  1.000 30.18884  ? 96  TYR B CD1 1 
ATOM   5650 C CD2 . TYR D 2 102 ? -10.73023 50.80868 18.21926  1.000 29.89779  ? 96  TYR B CD2 1 
ATOM   5651 C CE1 . TYR D 2 102 ? -11.35038 50.80343 20.90722  1.000 37.75634  ? 96  TYR B CE1 1 
ATOM   5652 C CE2 . TYR D 2 102 ? -11.44601 51.86176 18.75782  1.000 34.76115  ? 96  TYR B CE2 1 
ATOM   5653 C CZ  . TYR D 2 102 ? -11.75976 51.84987 20.10595  1.000 35.47573  ? 96  TYR B CZ  1 
ATOM   5654 O OH  . TYR D 2 102 ? -12.47431 52.88035 20.67181  1.000 34.89514  ? 96  TYR B OH  1 
ATOM   5655 N N   . ALA D 2 103 ? -9.03906  46.84582 16.00741  1.000 37.35733  ? 97  ALA B N   1 
ATOM   5656 C CA  . ALA D 2 103 ? -8.06758  46.12881 15.19017  1.000 32.89016  ? 97  ALA B CA  1 
ATOM   5657 C C   . ALA D 2 103 ? -7.46057  47.08770 14.17734  1.000 34.51344  ? 97  ALA B C   1 
ATOM   5658 O O   . ALA D 2 103 ? -8.18975  47.83229 13.51574  1.000 36.42439  ? 97  ALA B O   1 
ATOM   5659 C CB  . ALA D 2 103 ? -8.72018  44.94367 14.47677  1.000 34.21868  ? 97  ALA B CB  1 
ATOM   5660 N N   . PHE D 2 104 ? -6.13405  47.07641 14.06707  1.000 32.86178  ? 98  PHE B N   1 
ATOM   5661 C CA  . PHE D 2 104 ? -5.42422  47.84219 13.04643  1.000 35.51438  ? 98  PHE B CA  1 
ATOM   5662 C C   . PHE D 2 104 ? -5.18857  46.98814 11.81089  1.000 32.11295  ? 98  PHE B C   1 
ATOM   5663 O O   . PHE D 2 104 ? -4.96466  45.78098 11.90833  1.000 37.33427  ? 98  PHE B O   1 
ATOM   5664 C CB  . PHE D 2 104 ? -4.06515  48.33886 13.56057  1.000 29.42473  ? 98  PHE B CB  1 
ATOM   5665 C CG  . PHE D 2 104 ? -4.16353  49.34249 14.66711  1.000 33.54277  ? 98  PHE B CG  1 
ATOM   5666 C CD1 . PHE D 2 104 ? -4.22806  48.92860 15.99011  1.000 28.49107  ? 98  PHE B CD1 1 
ATOM   5667 C CD2 . PHE D 2 104 ? -4.17651  50.69919 14.38706  1.000 31.05005  ? 98  PHE B CD2 1 
ATOM   5668 C CE1 . PHE D 2 104 ? -4.32212  49.84224 17.01026  1.000 31.95417  ? 98  PHE B CE1 1 
ATOM   5669 C CE2 . PHE D 2 104 ? -4.26188  51.61946 15.40511  1.000 35.11788  ? 98  PHE B CE2 1 
ATOM   5670 C CZ  . PHE D 2 104 ? -4.33655  51.18994 16.72457  1.000 31.47169  ? 98  PHE B CZ  1 
ATOM   5671 N N   . GLY D 2 105 ? -5.23604  47.62596 10.64372  1.000 35.46079  ? 99  GLY B N   1 
ATOM   5672 C CA  . GLY D 2 105 ? -4.66552  47.02537 9.45426   1.000 35.91403  ? 99  GLY B CA  1 
ATOM   5673 C C   . GLY D 2 105 ? -3.15181  46.95167 9.56193   1.000 34.52574  ? 99  GLY B C   1 
ATOM   5674 O O   . GLY D 2 105 ? -2.52670  47.55351 10.43781  1.000 32.82701  ? 99  GLY B O   1 
ATOM   5675 N N   . GLN D 2 106 ? -2.53554  46.21249 8.64157   1.000 29.42850  ? 100 GLN B N   1 
ATOM   5676 C CA  . GLN D 2 106 ? -1.09973  45.96739 8.76371   1.000 32.02375  ? 100 GLN B CA  1 
ATOM   5677 C C   . GLN D 2 106 ? -0.23264  47.14748 8.32840   1.000 33.36184  ? 100 GLN B C   1 
ATOM   5678 O O   . GLN D 2 106 ? 0.99053   47.07581 8.48728   1.000 37.11734  ? 100 GLN B O   1 
ATOM   5679 C CB  . GLN D 2 106 ? -0.69406  44.72066 7.96866   1.000 26.72245  ? 100 GLN B CB  1 
ATOM   5680 C CG  . GLN D 2 106 ? -0.42396  44.96527 6.49702   1.000 41.96942  ? 100 GLN B CG  1 
ATOM   5681 C CD  . GLN D 2 106 ? -1.69878  45.00819 5.68005   1.000 48.35483  ? 100 GLN B CD  1 
ATOM   5682 O OE1 . GLN D 2 106 ? -2.79601  44.77896 6.20484   1.000 43.36590  ? 100 GLN B OE1 1 
ATOM   5683 N NE2 . GLN D 2 106 ? -1.56485  45.30102 4.38772   1.000 48.17674  ? 100 GLN B NE2 1 
ATOM   5684 N N   . GLY D 2 107 ? -0.81750  48.20730 7.79187   1.000 33.68062  ? 101 GLY B N   1 
ATOM   5685 C CA  . GLY D 2 107 ? -0.10789  49.40338 7.37392   1.000 31.02735  ? 101 GLY B CA  1 
ATOM   5686 C C   . GLY D 2 107 ? 0.23680   49.39524 5.89124   1.000 39.92413  ? 101 GLY B C   1 
ATOM   5687 O O   . GLY D 2 107 ? 0.42791   48.34330 5.27032   1.000 38.80299  ? 101 GLY B O   1 
ATOM   5688 N N   . THR D 2 108 ? 0.31605   50.59418 5.31117   1.000 31.85490  ? 102 THR B N   1 
ATOM   5689 C CA  . THR D 2 108 ? 0.72548   50.79870 3.91963   1.000 35.26811  ? 102 THR B CA  1 
ATOM   5690 C C   . THR D 2 108 ? 1.82465   51.85472 3.89653   1.000 35.94752  ? 102 THR B C   1 
ATOM   5691 O O   . THR D 2 108 ? 1.57500   53.01469 4.24047   1.000 31.96663  ? 102 THR B O   1 
ATOM   5692 C CB  . THR D 2 108 ? -0.45264  51.25271 3.04730   1.000 40.28025  ? 102 THR B CB  1 
ATOM   5693 O OG1 . THR D 2 108 ? -1.52607  50.31331 3.14803   1.000 32.82201  ? 102 THR B OG1 1 
ATOM   5694 C CG2 . THR D 2 108 ? -0.02797  51.40077 1.57876   1.000 36.49154  ? 102 THR B CG2 1 
ATOM   5695 N N   . LYS D 2 109 ? 3.02980   51.47262 3.47852   1.000 30.93182  ? 103 LYS B N   1 
ATOM   5696 C CA  . LYS D 2 109 ? 4.12210   52.43375 3.37710   1.000 35.39019  ? 103 LYS B CA  1 
ATOM   5697 C C   . LYS D 2 109 ? 4.04900   53.15064 2.03620   1.000 41.16290  ? 103 LYS B C   1 
ATOM   5698 O O   . LYS D 2 109 ? 3.86343   52.51328 0.99479   1.000 34.21898  ? 103 LYS B O   1 
ATOM   5699 C CB  . LYS D 2 109 ? 5.47636   51.74373 3.52761   1.000 36.80305  ? 103 LYS B CB  1 
ATOM   5700 C CG  . LYS D 2 109 ? 6.62388   52.71492 3.81752   1.000 49.55570  ? 103 LYS B CG  1 
ATOM   5701 C CD  . LYS D 2 109 ? 7.97318   52.01886 3.70172   1.000 61.84666  ? 103 LYS B CD  1 
ATOM   5702 C CE  . LYS D 2 109 ? 9.07453   52.79512 4.40869   1.000 64.79237  ? 103 LYS B CE  1 
ATOM   5703 N NZ  . LYS D 2 109 ? 9.01724   52.61683 5.88775   1.000 65.45504  ? 103 LYS B NZ  1 
ATOM   5704 N N   . VAL D 2 110 ? 4.19047   54.47441 2.06463   1.000 38.10718  ? 104 VAL B N   1 
ATOM   5705 C CA  . VAL D 2 110 ? 4.07556   55.31946 0.87806   1.000 40.08718  ? 104 VAL B CA  1 
ATOM   5706 C C   . VAL D 2 110 ? 5.41354   56.00039 0.64731   1.000 49.01714  ? 104 VAL B C   1 
ATOM   5707 O O   . VAL D 2 110 ? 5.89939   56.73749 1.51363   1.000 52.32363  ? 104 VAL B O   1 
ATOM   5708 C CB  . VAL D 2 110 ? 2.96370   56.36855 1.01702   1.000 39.43123  ? 104 VAL B CB  1 
ATOM   5709 C CG1 . VAL D 2 110 ? 3.06654   57.38726 -0.11038  1.000 46.35297  ? 104 VAL B CG1 1 
ATOM   5710 C CG2 . VAL D 2 110 ? 1.59398   55.70535 1.02104   1.000 40.31579  ? 104 VAL B CG2 1 
ATOM   5711 N N   . GLU D 2 111 ? 5.99852   55.76286 -0.51900  1.000 42.17855  ? 105 GLU B N   1 
ATOM   5712 C CA  . GLU D 2 111 ? 7.26970   56.34346 -0.91307  1.000 47.07931  ? 105 GLU B CA  1 
ATOM   5713 C C   . GLU D 2 111 ? 7.03877   57.29961 -2.08202  1.000 48.21575  ? 105 GLU B C   1 
ATOM   5714 O O   . GLU D 2 111 ? 6.07735   57.15146 -2.84495  1.000 40.38264  ? 105 GLU B O   1 
ATOM   5715 C CB  . GLU D 2 111 ? 8.26557   55.23401 -1.29276  1.000 41.64633  ? 105 GLU B CB  1 
ATOM   5716 C CG  . GLU D 2 111 ? 9.65421   55.71476 -1.68200  1.000 52.11074  ? 105 GLU B CG  1 
ATOM   5717 C CD  . GLU D 2 111 ? 10.36939  54.76747 -2.64317  1.000 51.51645  ? 105 GLU B CD  1 
ATOM   5718 O OE1 . GLU D 2 111 ? 9.94590   54.66767 -3.81834  1.000 49.26534  ? 105 GLU B OE1 1 
ATOM   5719 O OE2 . GLU D 2 111 ? 11.35720  54.12105 -2.22885  1.000 53.50460  ? 105 GLU B OE2 1 
ATOM   5720 N N   . ILE D 2 112 ? 7.91060   58.29956 -2.19946  1.000 36.38644  ? 106 ILE B N   1 
ATOM   5721 C CA  . ILE D 2 112 ? 7.83472   59.31037 -3.25271  1.000 44.61140  ? 106 ILE B CA  1 
ATOM   5722 C C   . ILE D 2 112 ? 8.85852   58.96849 -4.32689  1.000 40.39219  ? 106 ILE B C   1 
ATOM   5723 O O   . ILE D 2 112 ? 10.04478  58.80424 -4.02495  1.000 36.23175  ? 106 ILE B O   1 
ATOM   5724 C CB  . ILE D 2 112 ? 8.09122   60.72015 -2.68840  1.000 45.69960  ? 106 ILE B CB  1 
ATOM   5725 C CG1 . ILE D 2 112 ? 7.19870   60.99598 -1.46641  1.000 49.51332  ? 106 ILE B CG1 1 
ATOM   5726 C CG2 . ILE D 2 112 ? 7.90480   61.77113 -3.76476  1.000 45.13349  ? 106 ILE B CG2 1 
ATOM   5727 C CD1 . ILE D 2 112 ? 5.69885   60.85603 -1.71632  1.000 53.21456  ? 106 ILE B CD1 1 
ATOM   5728 N N   . LYS D 2 113 ? 8.41065   58.86412 -5.57712  1.000 37.75110  ? 107 LYS B N   1 
ATOM   5729 C CA  . LYS D 2 113 ? 9.32354   58.56465 -6.67738  1.000 36.39246  ? 107 LYS B CA  1 
ATOM   5730 C C   . LYS D 2 113 ? 10.21538  59.75960 -6.99762  1.000 42.86126  ? 107 LYS B C   1 
ATOM   5731 O O   . LYS D 2 113 ? 9.82009   60.91858 -6.85078  1.000 46.70948  ? 107 LYS B O   1 
ATOM   5732 C CB  . LYS D 2 113 ? 8.55023   58.16956 -7.93755  1.000 46.45341  ? 107 LYS B CB  1 
ATOM   5733 C CG  . LYS D 2 113 ? 8.11713   56.71504 -7.99824  1.000 44.81356  ? 107 LYS B CG  1 
ATOM   5734 C CD  . LYS D 2 113 ? 7.54347   56.36274 -9.36969  1.000 45.21252  ? 107 LYS B CD  1 
ATOM   5735 C CE  . LYS D 2 113 ? 6.85955   54.99909 -9.35160  1.000 43.20791  ? 107 LYS B CE  1 
ATOM   5736 N NZ  . LYS D 2 113 ? 7.68922   53.94593 -8.67708  1.000 52.30986  ? 107 LYS B NZ  1 
ATOM   5737 N N   . ARG D 2 114 ? 11.43378  59.46526 -7.44875  1.000 41.04114  ? 108 ARG B N   1 
ATOM   5738 C CA  . ARG D 2 114 ? 12.30474  60.47509 -8.03089  1.000 33.83953  ? 108 ARG B CA  1 
ATOM   5739 C C   . ARG D 2 114 ? 13.17404  59.81387 -9.09200  1.000 34.79582  ? 108 ARG B C   1 
ATOM   5740 O O   . ARG D 2 114 ? 13.08704  58.60660 -9.33565  1.000 40.30961  ? 108 ARG B O   1 
ATOM   5741 C CB  . ARG D 2 114 ? 13.16021  61.17840 -6.97068  1.000 39.51016  ? 108 ARG B CB  1 
ATOM   5742 C CG  . ARG D 2 114 ? 14.09255  60.27047 -6.18168  1.000 36.26370  ? 108 ARG B CG  1 
ATOM   5743 C CD  . ARG D 2 114 ? 15.24682  61.07924 -5.64560  1.000 38.92119  ? 108 ARG B CD  1 
ATOM   5744 N NE  . ARG D 2 114 ? 16.19541  61.37863 -6.70618  1.000 38.24590  ? 108 ARG B NE  1 
ATOM   5745 C CZ  . ARG D 2 114 ? 17.05434  62.38764 -6.69885  1.000 35.24760  ? 108 ARG B CZ  1 
ATOM   5746 N NH1 . ARG D 2 114 ? 17.10142  63.25060 -5.69962  1.000 31.15790  ? 108 ARG B NH1 1 
ATOM   5747 N NH2 . ARG D 2 114 ? 17.88639  62.53557 -7.72589  1.000 36.38212  ? 108 ARG B NH2 1 
ATOM   5748 N N   . THR D 2 115 ? 14.00938  60.62484 -9.73354  1.000 42.07629  ? 109 THR B N   1 
ATOM   5749 C CA  . THR D 2 115 ? 14.96767  60.10866 -10.69759 1.000 41.99426  ? 109 THR B CA  1 
ATOM   5750 C C   . THR D 2 115 ? 16.01358  59.25581 -9.99373  1.000 39.35982  ? 109 THR B C   1 
ATOM   5751 O O   . THR D 2 115 ? 16.30151  59.44576 -8.81121  1.000 41.75431  ? 109 THR B O   1 
ATOM   5752 C CB  . THR D 2 115 ? 15.65573  61.25569 -11.43277 1.000 44.11435  ? 109 THR B CB  1 
ATOM   5753 O OG1 . THR D 2 115 ? 16.28165  62.11952 -10.47894 1.000 41.26828  ? 109 THR B OG1 1 
ATOM   5754 C CG2 . THR D 2 115 ? 14.64499  62.05382 -12.23972 1.000 49.94950  ? 109 THR B CG2 1 
ATOM   5755 N N   . VAL D 2 116 ? 16.58293  58.30300 -10.73519 1.000 37.48392  ? 110 VAL B N   1 
ATOM   5756 C CA  . VAL D 2 116 ? 17.64729  57.47808 -10.18235 1.000 33.32276  ? 110 VAL B CA  1 
ATOM   5757 C C   . VAL D 2 116 ? 18.82521  58.36632 -9.80133  1.000 37.12547  ? 110 VAL B C   1 
ATOM   5758 O O   . VAL D 2 116 ? 19.11125  59.37345 -10.46288 1.000 38.12371  ? 110 VAL B O   1 
ATOM   5759 C CB  . VAL D 2 116 ? 18.04732  56.38999 -11.19307 1.000 37.73016  ? 110 VAL B CB  1 
ATOM   5760 C CG1 . VAL D 2 116 ? 19.22184  55.57873 -10.69217 1.000 39.73402  ? 110 VAL B CG1 1 
ATOM   5761 C CG2 . VAL D 2 116 ? 16.86964  55.47297 -11.46333 1.000 38.79317  ? 110 VAL B CG2 1 
ATOM   5762 N N   . ALA D 2 117 ? 19.49630  58.01568 -8.70181  1.000 34.27991  ? 111 ALA B N   1 
ATOM   5763 C CA  . ALA D 2 117 ? 20.70662  58.71126 -8.27614  1.000 29.84726  ? 111 ALA B CA  1 
ATOM   5764 C C   . ALA D 2 117 ? 21.67716  57.69961 -7.68111  1.000 33.43933  ? 111 ALA B C   1 
ATOM   5765 O O   . ALA D 2 117 ? 21.34352  57.00223 -6.71568  1.000 30.40145  ? 111 ALA B O   1 
ATOM   5766 C CB  . ALA D 2 117 ? 20.37871  59.81708 -7.27005  1.000 35.69609  ? 111 ALA B CB  1 
ATOM   5767 N N   . ALA D 2 118 ? 22.87000  57.61589 -8.26018  1.000 27.78060  ? 112 ALA B N   1 
ATOM   5768 C CA  . ALA D 2 118 ? 23.88095  56.69884 -7.76999  1.000 23.96970  ? 112 ALA B CA  1 
ATOM   5769 C C   . ALA D 2 118 ? 24.42626  57.16925 -6.41661  1.000 29.08634  ? 112 ALA B C   1 
ATOM   5770 O O   . ALA D 2 118 ? 24.52297  58.36910 -6.15489  1.000 25.41113  ? 112 ALA B O   1 
ATOM   5771 C CB  . ALA D 2 118 ? 25.02537  56.57582 -8.77115  1.000 29.12840  ? 112 ALA B CB  1 
ATOM   5772 N N   . PRO D 2 119 ? 24.79603  56.24307 -5.53877  1.000 32.76142  ? 113 PRO B N   1 
ATOM   5773 C CA  . PRO D 2 119 ? 25.37848  56.64512 -4.25353  1.000 28.22957  ? 113 PRO B CA  1 
ATOM   5774 C C   . PRO D 2 119 ? 26.84400  57.02600 -4.38036  1.000 26.60888  ? 113 PRO B C   1 
ATOM   5775 O O   . PRO D 2 119 ? 27.59117  56.47490 -5.19077  1.000 27.22254  ? 113 PRO B O   1 
ATOM   5776 C CB  . PRO D 2 119 ? 25.22497  55.38803 -3.39126  1.000 25.53266  ? 113 PRO B CB  1 
ATOM   5777 C CG  . PRO D 2 119 ? 25.34089  54.27118 -4.38937  1.000 30.24336  ? 113 PRO B CG  1 
ATOM   5778 C CD  . PRO D 2 119 ? 24.67261  54.77957 -5.66103  1.000 27.31451  ? 113 PRO B CD  1 
ATOM   5779 N N   . SER D 2 120 ? 27.24297  57.99807 -3.56810  1.000 23.52612  ? 114 SER B N   1 
ATOM   5780 C CA  . SER D 2 120 ? 28.64811  58.17616 -3.23320  1.000 25.32319  ? 114 SER B CA  1 
ATOM   5781 C C   . SER D 2 120 ? 29.00781  57.12488 -2.18891  1.000 27.67054  ? 114 SER B C   1 
ATOM   5782 O O   . SER D 2 120 ? 28.31108  56.98835 -1.17928  1.000 27.07247  ? 114 SER B O   1 
ATOM   5783 C CB  . SER D 2 120 ? 28.90656  59.57911 -2.67592  1.000 26.91024  ? 114 SER B CB  1 
ATOM   5784 O OG  . SER D 2 120 ? 28.45224  60.58212 -3.56362  1.000 40.18123  ? 114 SER B OG  1 
ATOM   5785 N N   . VAL D 2 121 ? 30.07752  56.37634 -2.43090  1.000 25.42717  ? 115 VAL B N   1 
ATOM   5786 C CA  . VAL D 2 121 ? 30.42907  55.21865 -1.61333  1.000 23.50322  ? 115 VAL B CA  1 
ATOM   5787 C C   . VAL D 2 121 ? 31.73462  55.50699 -0.88631  1.000 28.43885  ? 115 VAL B C   1 
ATOM   5788 O O   . VAL D 2 121 ? 32.72354  55.90637 -1.50873  1.000 25.33985  ? 115 VAL B O   1 
ATOM   5789 C CB  . VAL D 2 121 ? 30.54473  53.94016 -2.46324  1.000 22.18980  ? 115 VAL B CB  1 
ATOM   5790 C CG1 . VAL D 2 121 ? 30.85921  52.73180 -1.56245  1.000 21.73176  ? 115 VAL B CG1 1 
ATOM   5791 C CG2 . VAL D 2 121 ? 29.26364  53.70996 -3.24126  1.000 23.54958  ? 115 VAL B CG2 1 
ATOM   5792 N N   . PHE D 2 122 ? 31.73664  55.29777 0.43251   1.000 19.04758  ? 116 PHE B N   1 
ATOM   5793 C CA  . PHE D 2 122 ? 32.90741  55.51415 1.26636   1.000 18.34441  ? 116 PHE B CA  1 
ATOM   5794 C C   . PHE D 2 122 ? 33.14991  54.25044 2.07201   1.000 22.26585  ? 116 PHE B C   1 
ATOM   5795 O O   . PHE D 2 122 ? 32.19981  53.61939 2.52720   1.000 21.70895  ? 116 PHE B O   1 
ATOM   5796 C CB  . PHE D 2 122 ? 32.70160  56.68908 2.22727   1.000 24.61108  ? 116 PHE B CB  1 
ATOM   5797 C CG  . PHE D 2 122 ? 32.37002  57.99063 1.55726   1.000 21.75802  ? 116 PHE B CG  1 
ATOM   5798 C CD1 . PHE D 2 122 ? 31.06456  58.29065 1.20458   1.000 22.56057  ? 116 PHE B CD1 1 
ATOM   5799 C CD2 . PHE D 2 122 ? 33.36337  58.92451 1.31361   1.000 21.95296  ? 116 PHE B CD2 1 
ATOM   5800 C CE1 . PHE D 2 122 ? 30.75078  59.49864 0.61671   1.000 24.57762  ? 116 PHE B CE1 1 
ATOM   5801 C CE2 . PHE D 2 122 ? 33.06346  60.12857 0.70966   1.000 27.43090  ? 116 PHE B CE2 1 
ATOM   5802 C CZ  . PHE D 2 122 ? 31.75045  60.41415 0.35865   1.000 24.20756  ? 116 PHE B CZ  1 
ATOM   5803 N N   . ILE D 2 123 ? 34.40558  53.87048 2.25800   1.000 20.30950  ? 117 ILE B N   1 
ATOM   5804 C CA  . ILE D 2 123 ? 34.71194  52.73216 3.11042   1.000 19.79708  ? 117 ILE B CA  1 
ATOM   5805 C C   . ILE D 2 123 ? 35.63648  53.20142 4.22829   1.000 23.64069  ? 117 ILE B C   1 
ATOM   5806 O O   . ILE D 2 123 ? 36.55283  53.99713 3.99771   1.000 24.30667  ? 117 ILE B O   1 
ATOM   5807 C CB  . ILE D 2 123 ? 35.30466  51.56462 2.29349   1.000 19.15502  ? 117 ILE B CB  1 
ATOM   5808 C CG1 . ILE D 2 123 ? 35.51642  50.32733 3.17824   1.000 18.37243  ? 117 ILE B CG1 1 
ATOM   5809 C CG2 . ILE D 2 123 ? 36.58232  51.97151 1.54553   1.000 25.53688  ? 117 ILE B CG2 1 
ATOM   5810 C CD1 . ILE D 2 123 ? 36.05140  49.11606 2.35138   1.000 20.48496  ? 117 ILE B CD1 1 
ATOM   5811 N N   . PHE D 2 124 ? 35.35588  52.75061 5.45272   1.000 22.15075  ? 118 PHE B N   1 
ATOM   5812 C CA  . PHE D 2 124 ? 36.09466  53.16644 6.64506   1.000 18.21841  ? 118 PHE B CA  1 
ATOM   5813 C C   . PHE D 2 124 ? 36.76844  51.95827 7.28894   1.000 23.98234  ? 118 PHE B C   1 
ATOM   5814 O O   . PHE D 2 124 ? 36.06716  51.01757 7.70627   1.000 21.82344  ? 118 PHE B O   1 
ATOM   5815 C CB  . PHE D 2 124 ? 35.15700  53.81342 7.66313   1.000 19.81810  ? 118 PHE B CB  1 
ATOM   5816 C CG  . PHE D 2 124 ? 34.50408  55.07665 7.20199   1.000 16.52042  ? 118 PHE B CG  1 
ATOM   5817 C CD1 . PHE D 2 124 ? 35.15057  56.29462 7.32590   1.000 20.29726  ? 118 PHE B CD1 1 
ATOM   5818 C CD2 . PHE D 2 124 ? 33.21723  55.05982 6.71385   1.000 19.57857  ? 118 PHE B CD2 1 
ATOM   5819 C CE1 . PHE D 2 124 ? 34.52540  57.47584 6.93477   1.000 19.10967  ? 118 PHE B CE1 1 
ATOM   5820 C CE2 . PHE D 2 124 ? 32.58756  56.23523 6.32586   1.000 25.91109  ? 118 PHE B CE2 1 
ATOM   5821 C CZ  . PHE D 2 124 ? 33.25210  57.44202 6.43268   1.000 21.63839  ? 118 PHE B CZ  1 
ATOM   5822 N N   . PRO D 2 125 ? 38.08752  51.93039 7.43096   1.000 23.92194  ? 119 PRO B N   1 
ATOM   5823 C CA  . PRO D 2 125 ? 38.73590  50.82484 8.16394   1.000 22.40474  ? 119 PRO B CA  1 
ATOM   5824 C C   . PRO D 2 125 ? 38.40225  50.90733 9.64474   1.000 26.00954  ? 119 PRO B C   1 
ATOM   5825 O O   . PRO D 2 125 ? 37.87186  51.92650 10.10799  1.000 18.08025  ? 119 PRO B O   1 
ATOM   5826 C CB  . PRO D 2 125 ? 40.23735  51.06138 7.92071   1.000 25.29879  ? 119 PRO B CB  1 
ATOM   5827 C CG  . PRO D 2 125 ? 40.32102  52.11067 6.82570   1.000 27.82333  ? 119 PRO B CG  1 
ATOM   5828 C CD  . PRO D 2 125 ? 39.05816  52.91028 6.90926   1.000 29.34831  ? 119 PRO B CD  1 
ATOM   5829 N N   . PRO D 2 126 ? 38.66929  49.86482 10.42366  1.000 25.41384  ? 120 PRO B N   1 
ATOM   5830 C CA  . PRO D 2 126 ? 38.47690  49.98926 11.87630  1.000 28.32397  ? 120 PRO B CA  1 
ATOM   5831 C C   . PRO D 2 126 ? 39.45888  50.98927 12.46528  1.000 28.89360  ? 120 PRO B C   1 
ATOM   5832 O O   . PRO D 2 126 ? 40.57971  51.15371 11.98042  1.000 26.30974  ? 120 PRO B O   1 
ATOM   5833 C CB  . PRO D 2 126 ? 38.73653  48.57334 12.40135  1.000 23.85648  ? 120 PRO B CB  1 
ATOM   5834 C CG  . PRO D 2 126 ? 39.56738  47.91317 11.33756  1.000 29.44430  ? 120 PRO B CG  1 
ATOM   5835 C CD  . PRO D 2 126 ? 39.10193  48.51131 10.03298  1.000 30.27404  ? 120 PRO B CD  1 
ATOM   5836 N N   . SER D 2 127 ? 39.01324  51.68905 13.50256  1.000 26.21100  ? 121 SER B N   1 
ATOM   5837 C CA  . SER D 2 127 ? 39.89817  52.62747 14.17474  1.000 31.62099  ? 121 SER B CA  1 
ATOM   5838 C C   . SER D 2 127 ? 40.92199  51.86387 14.99642  1.000 26.84561  ? 121 SER B C   1 
ATOM   5839 O O   . SER D 2 127 ? 40.66242  50.75767 15.47486  1.000 27.71671  ? 121 SER B O   1 
ATOM   5840 C CB  . SER D 2 127 ? 39.11232  53.55635 15.09289  1.000 28.35138  ? 121 SER B CB  1 
ATOM   5841 O OG  . SER D 2 127 ? 38.56932  52.81063 16.17723  1.000 25.33422  ? 121 SER B OG  1 
ATOM   5842 N N   . ASP D 2 128 ? 42.10296  52.45943 15.14885  1.000 29.70037  ? 122 ASP B N   1 
ATOM   5843 C CA  . ASP D 2 128 ? 43.09883  51.86479 16.03465  1.000 36.30671  ? 122 ASP B CA  1 
ATOM   5844 C C   . ASP D 2 128 ? 42.54996  51.70133 17.44902  1.000 37.90979  ? 122 ASP B C   1 
ATOM   5845 O O   . ASP D 2 128 ? 42.84092  50.69949 18.11619  1.000 39.76307  ? 122 ASP B O   1 
ATOM   5846 C CB  . ASP D 2 128 ? 44.36816  52.71650 16.03900  1.000 39.38954  ? 122 ASP B CB  1 
ATOM   5847 C CG  . ASP D 2 128 ? 45.12066  52.65108 14.71929  1.000 52.52767  ? 122 ASP B CG  1 
ATOM   5848 O OD1 . ASP D 2 128 ? 44.89008  51.69450 13.94155  1.000 43.09322  ? 122 ASP B OD1 1 
ATOM   5849 O OD2 . ASP D 2 128 ? 45.94778  53.55688 14.46026  1.000 58.97966  ? 122 ASP B OD2 1 
ATOM   5850 N N   . GLU D 2 129 ? 41.72462  52.65305 17.90383  1.000 27.36760  ? 123 GLU B N   1 
ATOM   5851 C CA  . GLU D 2 129 ? 41.15351  52.56380 19.24510  1.000 29.76751  ? 123 GLU B CA  1 
ATOM   5852 C C   . GLU D 2 129 ? 40.32724  51.29500 19.40763  1.000 34.22301  ? 123 GLU B C   1 
ATOM   5853 O O   . GLU D 2 129 ? 40.46799  50.58511 20.40692  1.000 36.36294  ? 123 GLU B O   1 
ATOM   5854 C CB  . GLU D 2 129 ? 40.31026  53.80425 19.54117  1.000 33.76211  ? 123 GLU B CB  1 
ATOM   5855 C CG  . GLU D 2 129 ? 39.66897  53.81702 20.92324  1.000 34.41216  ? 123 GLU B CG  1 
ATOM   5856 C CD  . GLU D 2 129 ? 38.72296  54.99892 21.12918  1.000 46.19541  ? 123 GLU B CD  1 
ATOM   5857 O OE1 . GLU D 2 129 ? 38.65719  55.89085 20.24706  1.000 45.64813  ? 123 GLU B OE1 1 
ATOM   5858 O OE2 . GLU D 2 129 ? 38.04164  55.03322 22.17982  1.000 43.38591  ? 123 GLU B OE2 1 
ATOM   5859 N N   . GLN D 2 130 ? 39.48890  50.96521 18.41503  1.000 29.60554  ? 124 GLN B N   1 
ATOM   5860 C CA  . GLN D 2 130 ? 38.65303  49.76924 18.52735  1.000 29.42393  ? 124 GLN B CA  1 
ATOM   5861 C C   . GLN D 2 130 ? 39.46790  48.48709 18.39923  1.000 32.49900  ? 124 GLN B C   1 
ATOM   5862 O O   . GLN D 2 130 ? 39.11521  47.47088 19.00987  1.000 37.28507  ? 124 GLN B O   1 
ATOM   5863 C CB  . GLN D 2 130 ? 37.53108  49.77146 17.47382  1.000 28.29436  ? 124 GLN B CB  1 
ATOM   5864 C CG  . GLN D 2 130 ? 36.62213  48.53657 17.58858  1.000 29.62014  ? 124 GLN B CG  1 
ATOM   5865 C CD  . GLN D 2 130 ? 35.68906  48.33108 16.40723  1.000 32.36231  ? 124 GLN B CD  1 
ATOM   5866 O OE1 . GLN D 2 130 ? 35.99431  48.69585 15.25703  1.000 20.66877  ? 124 GLN B OE1 1 
ATOM   5867 N NE2 . GLN D 2 130 ? 34.54350  47.71890 16.68371  1.000 29.66095  ? 124 GLN B NE2 1 
ATOM   5868 N N   . LEU D 2 131 ? 40.54202  48.50268 17.60714  1.000 31.59469  ? 125 LEU B N   1 
ATOM   5869 C CA  . LEU D 2 131 ? 41.32673  47.28460 17.41554  1.000 41.34935  ? 125 LEU B CA  1 
ATOM   5870 C C   . LEU D 2 131 ? 41.94476  46.80591 18.72851  1.000 40.55753  ? 125 LEU B C   1 
ATOM   5871 O O   . LEU D 2 131 ? 42.05180  45.59811 18.97288  1.000 42.40353  ? 125 LEU B O   1 
ATOM   5872 C CB  . LEU D 2 131 ? 42.40262  47.52134 16.35769  1.000 34.16123  ? 125 LEU B CB  1 
ATOM   5873 C CG  . LEU D 2 131 ? 41.84209  47.45397 14.93902  1.000 35.25635  ? 125 LEU B CG  1 
ATOM   5874 C CD1 . LEU D 2 131 ? 42.85766  47.95622 13.91233  1.000 29.98736  ? 125 LEU B CD1 1 
ATOM   5875 C CD2 . LEU D 2 131 ? 41.41035  46.02005 14.62921  1.000 25.29109  ? 125 LEU B CD2 1 
ATOM   5876 N N   . LYS D 2 132 ? 42.34754  47.73955 19.58827  1.000 40.97652  ? 126 LYS B N   1 
ATOM   5877 C CA  . LYS D 2 132 ? 42.89015  47.38217 20.89453  1.000 46.29257  ? 126 LYS B CA  1 
ATOM   5878 C C   . LYS D 2 132 ? 41.88518  46.61851 21.74721  1.000 48.38901  ? 126 LYS B C   1 
ATOM   5879 O O   . LYS D 2 132 ? 42.29325  45.89589 22.65974  1.000 55.11336  ? 126 LYS B O   1 
ATOM   5880 C CB  . LYS D 2 132 ? 43.35125  48.64744 21.61011  1.000 39.26619  ? 126 LYS B CB  1 
ATOM   5881 C CG  . LYS D 2 132 ? 44.44618  49.38949 20.85843  1.000 43.99719  ? 126 LYS B CG  1 
ATOM   5882 C CD  . LYS D 2 132 ? 44.82657  50.69460 21.55040  1.000 55.16631  ? 126 LYS B CD  1 
ATOM   5883 C CE  . LYS D 2 132 ? 44.19080  51.89933 20.86733  1.000 49.43316  ? 126 LYS B CE  1 
ATOM   5884 N NZ  . LYS D 2 132 ? 44.43110  53.19246 21.59763  1.000 51.75223  ? 126 LYS B NZ  1 
ATOM   5885 N N   . SER D 2 133 ? 40.58566  46.75020 21.45448  1.000 49.76797  ? 127 SER B N   1 
ATOM   5886 C CA  . SER D 2 133 ? 39.51268  46.02902 22.13092  1.000 49.46339  ? 127 SER B CA  1 
ATOM   5887 C C   . SER D 2 133 ? 39.31801  44.60998 21.61386  1.000 46.77499  ? 127 SER B C   1 
ATOM   5888 O O   . SER D 2 133 ? 38.51759  43.86496 22.18856  1.000 48.14406  ? 127 SER B O   1 
ATOM   5889 C CB  . SER D 2 133 ? 38.18968  46.78608 21.97547  1.000 46.84751  ? 127 SER B CB  1 
ATOM   5890 O OG  . SER D 2 133 ? 38.39857  48.19111 21.94349  1.000 57.60285  ? 127 SER B OG  1 
ATOM   5891 N N   . GLY D 2 134 ? 39.99508  44.22400 20.53894  1.000 43.05737  ? 128 GLY B N   1 
ATOM   5892 C CA  . GLY D 2 134 ? 39.87698  42.87745 20.01372  1.000 38.78062  ? 128 GLY B CA  1 
ATOM   5893 C C   . GLY D 2 134 ? 38.81898  42.67850 18.95353  1.000 43.98031  ? 128 GLY B C   1 
ATOM   5894 O O   . GLY D 2 134 ? 38.57327  41.53280 18.55199  1.000 38.55618  ? 128 GLY B O   1 
ATOM   5895 N N   . THR D 2 135 ? 38.18336  43.75028 18.48999  1.000 40.03289  ? 129 THR B N   1 
ATOM   5896 C CA  . THR D 2 135 ? 37.13898  43.67368 17.48190  1.000 33.24230  ? 129 THR B CA  1 
ATOM   5897 C C   . THR D 2 135 ? 37.42887  44.70362 16.40006  1.000 30.57664  ? 129 THR B C   1 
ATOM   5898 O O   . THR D 2 135 ? 38.00761  45.76214 16.66359  1.000 30.66222  ? 129 THR B O   1 
ATOM   5899 C CB  . THR D 2 135 ? 35.75062  43.91052 18.10243  1.000 36.02761  ? 129 THR B CB  1 
ATOM   5900 O OG1 . THR D 2 135 ? 35.63622  43.13808 19.30348  1.000 47.36802  ? 129 THR B OG1 1 
ATOM   5901 C CG2 . THR D 2 135 ? 34.64637  43.49394 17.13738  1.000 37.42643  ? 129 THR B CG2 1 
ATOM   5902 N N   . ALA D 2 136 ? 37.03830  44.37759 15.17270  1.000 31.16710  ? 130 ALA B N   1 
ATOM   5903 C CA  . ALA D 2 136 ? 37.25405  45.25648 14.03221  1.000 25.46929  ? 130 ALA B CA  1 
ATOM   5904 C C   . ALA D 2 136 ? 35.93475  45.40489 13.30077  1.000 32.93547  ? 130 ALA B C   1 
ATOM   5905 O O   . ALA D 2 136 ? 35.38465  44.41448 12.80787  1.000 30.62864  ? 130 ALA B O   1 
ATOM   5906 C CB  . ALA D 2 136 ? 38.32786  44.69373 13.10088  1.000 24.36564  ? 130 ALA B CB  1 
ATOM   5907 N N   . SER D 2 137 ? 35.41883  46.62596 13.24586  1.000 20.76292  ? 131 SER B N   1 
ATOM   5908 C CA  . SER D 2 137 ? 34.23577  46.92895 12.45606  1.000 18.88610  ? 131 SER B CA  1 
ATOM   5909 C C   . SER D 2 137 ? 34.67150  47.71653 11.22681  1.000 27.73621  ? 131 SER B C   1 
ATOM   5910 O O   . SER D 2 137 ? 35.29751  48.77658 11.35231  1.000 22.87421  ? 131 SER B O   1 
ATOM   5911 C CB  . SER D 2 137 ? 33.20486  47.71589 13.26551  1.000 23.59602  ? 131 SER B CB  1 
ATOM   5912 O OG  . SER D 2 137 ? 32.79464  47.02017 14.43505  1.000 31.36743  ? 131 SER B OG  1 
ATOM   5913 N N   . VAL D 2 138 ? 34.33573  47.19647 10.04945  1.000 21.42427  ? 132 VAL B N   1 
ATOM   5914 C CA  . VAL D 2 138 ? 34.58181  47.86117 8.77709   1.000 22.40217  ? 132 VAL B CA  1 
ATOM   5915 C C   . VAL D 2 138 ? 33.24607  48.38478 8.28950   1.000 21.29034  ? 132 VAL B C   1 
ATOM   5916 O O   . VAL D 2 138 ? 32.26986  47.62911 8.22837   1.000 23.57338  ? 132 VAL B O   1 
ATOM   5917 C CB  . VAL D 2 138 ? 35.19412  46.89687 7.74869   1.000 22.09018  ? 132 VAL B CB  1 
ATOM   5918 C CG1 . VAL D 2 138 ? 35.80771  47.68180 6.61112   1.000 21.19456  ? 132 VAL B CG1 1 
ATOM   5919 C CG2 . VAL D 2 138 ? 36.22554  46.00344 8.39936   1.000 22.94722  ? 132 VAL B CG2 1 
ATOM   5920 N N   . VAL D 2 139 ? 33.18377  49.67090 7.95723   1.000 18.19385  ? 133 VAL B N   1 
ATOM   5921 C CA  . VAL D 2 139 ? 31.91443  50.29010 7.59929   1.000 19.47980  ? 133 VAL B CA  1 
ATOM   5922 C C   . VAL D 2 139 ? 31.97371  50.75911 6.15358   1.000 23.29425  ? 133 VAL B C   1 
ATOM   5923 O O   . VAL D 2 139 ? 32.97191  51.34465 5.71418   1.000 23.12673  ? 133 VAL B O   1 
ATOM   5924 C CB  . VAL D 2 139 ? 31.53983  51.45688 8.53463   1.000 21.76010  ? 133 VAL B CB  1 
ATOM   5925 C CG1 . VAL D 2 139 ? 30.25615  52.11888 8.04398   1.000 18.62169  ? 133 VAL B CG1 1 
ATOM   5926 C CG2 . VAL D 2 139 ? 31.33147  50.94909 9.96405   1.000 24.02629  ? 133 VAL B CG2 1 
ATOM   5927 N N   . CYS D 2 140 ? 30.89081  50.49629 5.42718   1.000 18.07583  ? 134 CYS B N   1 
ATOM   5928 C CA  . CYS D 2 140 ? 30.67755  50.95586 4.06477   1.000 21.21480  ? 134 CYS B CA  1 
ATOM   5929 C C   . CYS D 2 140 ? 29.44763  51.85306 4.06843   1.000 27.05354  ? 134 CYS B C   1 
ATOM   5930 O O   . CYS D 2 140 ? 28.39509  51.46189 4.58394   1.000 25.32816  ? 134 CYS B O   1 
ATOM   5931 C CB  . CYS D 2 140 ? 30.49267  49.75272 3.13595   1.000 21.20233  ? 134 CYS B CB  1 
ATOM   5932 S SG  . CYS D 2 140 ? 30.36110  50.10170 1.36629   1.000 33.27201  ? 134 CYS B SG  1 
ATOM   5933 N N   . LEU D 2 141 ? 29.58780  53.06728 3.54131   1.000 20.51923  ? 135 LEU B N   1 
ATOM   5934 C CA  . LEU D 2 141 ? 28.49809  54.03336 3.49641   1.000 15.70630  ? 135 LEU B CA  1 
ATOM   5935 C C   . LEU D 2 141 ? 28.09374  54.29941 2.05258   1.000 21.73902  ? 135 LEU B C   1 
ATOM   5936 O O   . LEU D 2 141 ? 28.95189  54.56166 1.20670   1.000 20.16566  ? 135 LEU B O   1 
ATOM   5937 C CB  . LEU D 2 141 ? 28.91614  55.34016 4.16652   1.000 19.78604  ? 135 LEU B CB  1 
ATOM   5938 C CG  . LEU D 2 141 ? 28.06992  56.58153 3.87319   1.000 23.30332  ? 135 LEU B CG  1 
ATOM   5939 C CD1 . LEU D 2 141 ? 26.67471  56.49268 4.49544   1.000 26.00307  ? 135 LEU B CD1 1 
ATOM   5940 C CD2 . LEU D 2 141 ? 28.79369  57.81880 4.35354   1.000 21.34777  ? 135 LEU B CD2 1 
ATOM   5941 N N   . LEU D 2 142 ? 26.79578  54.21695 1.78240   1.000 24.94038  ? 136 LEU B N   1 
ATOM   5942 C CA  . LEU D 2 142 ? 26.18097  54.60015 0.50917   1.000 24.25517  ? 136 LEU B CA  1 
ATOM   5943 C C   . LEU D 2 142 ? 25.35388  55.84267 0.79492   1.000 21.21722  ? 136 LEU B C   1 
ATOM   5944 O O   . LEU D 2 142 ? 24.34146  55.77054 1.49785   1.000 23.72917  ? 136 LEU B O   1 
ATOM   5945 C CB  . LEU D 2 142 ? 25.28929  53.49223 -0.04857  1.000 20.29074  ? 136 LEU B CB  1 
ATOM   5946 C CG  . LEU D 2 142 ? 25.84150  52.18507 -0.63623  1.000 23.28987  ? 136 LEU B CG  1 
ATOM   5947 C CD1 . LEU D 2 142 ? 26.74031  51.46343 0.33044   1.000 24.60884  ? 136 LEU B CD1 1 
ATOM   5948 C CD2 . LEU D 2 142 ? 24.67327  51.28147 -1.00800  1.000 22.94570  ? 136 LEU B CD2 1 
ATOM   5949 N N   . ASN D 2 143 ? 25.77162  56.97726 0.25895   1.000 19.29940  ? 137 ASN B N   1 
ATOM   5950 C CA  . ASN D 2 143 ? 25.18246  58.25847 0.61667   1.000 21.94596  ? 137 ASN B CA  1 
ATOM   5951 C C   . ASN D 2 143 ? 24.27014  58.78366 -0.49232  1.000 28.27266  ? 137 ASN B C   1 
ATOM   5952 O O   . ASN D 2 143 ? 24.68447  58.87658 -1.65169  1.000 27.10994  ? 137 ASN B O   1 
ATOM   5953 C CB  . ASN D 2 143 ? 26.28845  59.27026 0.91015   1.000 25.13552  ? 137 ASN B CB  1 
ATOM   5954 C CG  . ASN D 2 143 ? 25.81615  60.39561 1.77587   1.000 32.48320  ? 137 ASN B CG  1 
ATOM   5955 O OD1 . ASN D 2 143 ? 25.38071  60.17539 2.90293   1.000 38.00275  ? 137 ASN B OD1 1 
ATOM   5956 N ND2 . ASN D 2 143 ? 25.89604  61.61765 1.25949   1.000 41.97914  ? 137 ASN B ND2 1 
ATOM   5957 N N   . ASN D 2 144 ? 23.02858  59.11404 -0.13101  1.000 28.66485  ? 138 ASN B N   1 
ATOM   5958 C CA  . ASN D 2 144 ? 22.12105  59.92604 -0.95843  1.000 30.91989  ? 138 ASN B CA  1 
ATOM   5959 C C   . ASN D 2 144 ? 21.85305  59.30213 -2.33043  1.000 28.26670  ? 138 ASN B C   1 
ATOM   5960 O O   . ASN D 2 144 ? 22.13035  59.90330 -3.36488  1.000 32.57566  ? 138 ASN B O   1 
ATOM   5961 C CB  . ASN D 2 144 ? 22.66885  61.34892 -1.13484  1.000 27.43439  ? 138 ASN B CB  1 
ATOM   5962 C CG  . ASN D 2 144 ? 22.61936  62.16959 0.14682   1.000 40.19591  ? 138 ASN B CG  1 
ATOM   5963 O OD1 . ASN D 2 144 ? 22.57592  61.62862 1.25050   1.000 35.19269  ? 138 ASN B OD1 1 
ATOM   5964 N ND2 . ASN D 2 144 ? 22.62597  63.49005 -0.00269  1.000 45.72808  ? 138 ASN B ND2 1 
ATOM   5965 N N   . PHE D 2 145 ? 21.27928  58.10151 -2.33282  1.000 25.13710  ? 139 PHE B N   1 
ATOM   5966 C CA  . PHE D 2 145 ? 20.97006  57.40096 -3.56902  1.000 24.04903  ? 139 PHE B CA  1 
ATOM   5967 C C   . PHE D 2 145 ? 19.47132  57.12699 -3.67302  1.000 30.35897  ? 139 PHE B C   1 
ATOM   5968 O O   . PHE D 2 145 ? 18.71594  57.26177 -2.70729  1.000 31.66822  ? 139 PHE B O   1 
ATOM   5969 C CB  . PHE D 2 145 ? 21.76639  56.09003 -3.67647  1.000 28.87089  ? 139 PHE B CB  1 
ATOM   5970 C CG  . PHE D 2 145 ? 21.42303  55.07331 -2.62130  1.000 32.59071  ? 139 PHE B CG  1 
ATOM   5971 C CD1 . PHE D 2 145 ? 22.00151  55.13875 -1.35360  1.000 27.28923  ? 139 PHE B CD1 1 
ATOM   5972 C CD2 . PHE D 2 145 ? 20.54484  54.03614 -2.90024  1.000 26.01560  ? 139 PHE B CD2 1 
ATOM   5973 C CE1 . PHE D 2 145 ? 21.68767  54.19574 -0.37261  1.000 29.44029  ? 139 PHE B CE1 1 
ATOM   5974 C CE2 . PHE D 2 145 ? 20.22657  53.08960 -1.92929  1.000 29.36589  ? 139 PHE B CE2 1 
ATOM   5975 C CZ  . PHE D 2 145 ? 20.80950  53.16896 -0.65468  1.000 26.82296  ? 139 PHE B CZ  1 
ATOM   5976 N N   . TYR D 2 146 ? 19.03918  56.75733 -4.88709  1.000 29.31331  ? 140 TYR B N   1 
ATOM   5977 C CA  . TYR D 2 146 ? 17.67356  56.33790 -5.18093  1.000 24.92070  ? 140 TYR B CA  1 
ATOM   5978 C C   . TYR D 2 146 ? 17.74979  55.44247 -6.40203  1.000 33.21699  ? 140 TYR B C   1 
ATOM   5979 O O   . TYR D 2 146 ? 18.44952  55.80263 -7.35816  1.000 31.04036  ? 140 TYR B O   1 
ATOM   5980 C CB  . TYR D 2 146 ? 16.72876  57.51375 -5.45737  1.000 27.14116  ? 140 TYR B CB  1 
ATOM   5981 C CG  . TYR D 2 146 ? 15.29878  57.04353 -5.61267  1.000 33.71627  ? 140 TYR B CG  1 
ATOM   5982 C CD1 . TYR D 2 146 ? 14.46511  56.92399 -4.49880  1.000 36.71364  ? 140 TYR B CD1 1 
ATOM   5983 C CD2 . TYR D 2 146 ? 14.79030  56.67160 -6.85274  1.000 31.74938  ? 140 TYR B CD2 1 
ATOM   5984 C CE1 . TYR D 2 146 ? 13.16210  56.46719 -4.61877  1.000 34.17887  ? 140 TYR B CE1 1 
ATOM   5985 C CE2 . TYR D 2 146 ? 13.48343  56.20370 -6.97888  1.000 31.31853  ? 140 TYR B CE2 1 
ATOM   5986 C CZ  . TYR D 2 146 ? 12.67831  56.10874 -5.86028  1.000 36.00454  ? 140 TYR B CZ  1 
ATOM   5987 O OH  . TYR D 2 146 ? 11.38798  55.65436 -5.97189  1.000 36.21505  ? 140 TYR B OH  1 
ATOM   5988 N N   . PRO D 2 147 ? 17.03157  54.30195 -6.43770  1.000 28.79089  ? 141 PRO B N   1 
ATOM   5989 C CA  . PRO D 2 147 ? 16.06772  53.80563 -5.45253  1.000 31.28076  ? 141 PRO B CA  1 
ATOM   5990 C C   . PRO D 2 147 ? 16.69971  53.06191 -4.26975  1.000 31.70925  ? 141 PRO B C   1 
ATOM   5991 O O   . PRO D 2 147 ? 17.91736  52.86282 -4.25510  1.000 26.81814  ? 141 PRO B O   1 
ATOM   5992 C CB  . PRO D 2 147 ? 15.20285  52.85712 -6.28508  1.000 32.52397  ? 141 PRO B CB  1 
ATOM   5993 C CG  . PRO D 2 147 ? 16.15138  52.30129 -7.26551  1.000 34.06117  ? 141 PRO B CG  1 
ATOM   5994 C CD  . PRO D 2 147 ? 17.04449  53.45019 -7.64318  1.000 34.77387  ? 141 PRO B CD  1 
ATOM   5995 N N   . ARG D 2 148 ? 15.87722  52.63711 -3.30220  1.000 32.97918  ? 142 ARG B N   1 
ATOM   5996 C CA  . ARG D 2 148 ? 16.42903  52.06966 -2.06914  1.000 36.94883  ? 142 ARG B CA  1 
ATOM   5997 C C   . ARG D 2 148 ? 17.13562  50.73668 -2.31694  1.000 37.28464  ? 142 ARG B C   1 
ATOM   5998 O O   . ARG D 2 148 ? 18.14296  50.43847 -1.66711  1.000 30.43155  ? 142 ARG B O   1 
ATOM   5999 C CB  . ARG D 2 148 ? 15.33739  51.89358 -1.00816  1.000 35.85740  ? 142 ARG B CB  1 
ATOM   6000 C CG  . ARG D 2 148 ? 15.87527  51.29097 0.30332   1.000 32.74608  ? 142 ARG B CG  1 
ATOM   6001 C CD  . ARG D 2 148 ? 14.81553  51.10058 1.38121   1.000 47.39472  ? 142 ARG B CD  1 
ATOM   6002 N NE  . ARG D 2 148 ? 13.60314  50.49495 0.84749   1.000 55.82531  ? 142 ARG B NE  1 
ATOM   6003 C CZ  . ARG D 2 148 ? 12.40883  51.07204 0.86474   1.000 69.28417  ? 142 ARG B CZ  1 
ATOM   6004 N NH1 . ARG D 2 148 ? 12.21434  52.24475 1.44938   1.000 64.93101  ? 142 ARG B NH1 1 
ATOM   6005 N NH2 . ARG D 2 148 ? 11.38213  50.45623 0.28402   1.000 75.01733  ? 142 ARG B NH2 1 
ATOM   6006 N N   . GLU D 2 149 ? 16.64376  49.92818 -3.25334  1.000 32.41512  ? 143 GLU B N   1 
ATOM   6007 C CA  . GLU D 2 149 ? 17.18229  48.58155 -3.41207  1.000 35.49023  ? 143 GLU B CA  1 
ATOM   6008 C C   . GLU D 2 149 ? 18.62434  48.62105 -3.91159  1.000 40.35033  ? 143 GLU B C   1 
ATOM   6009 O O   . GLU D 2 149 ? 18.94368  49.30947 -4.88871  1.000 36.96442  ? 143 GLU B O   1 
ATOM   6010 C CB  . GLU D 2 149 ? 16.32077  47.75942 -4.37044  1.000 37.57949  ? 143 GLU B CB  1 
ATOM   6011 C CG  . GLU D 2 149 ? 16.64361  46.26487 -4.31173  1.000 49.96949  ? 143 GLU B CG  1 
ATOM   6012 C CD  . GLU D 2 149 ? 15.95141  45.43817 -5.39029  1.000 73.12544  ? 143 GLU B CD  1 
ATOM   6013 O OE1 . GLU D 2 149 ? 15.58393  45.99413 -6.45404  1.000 66.12800  ? 143 GLU B OE1 1 
ATOM   6014 O OE2 . GLU D 2 149 ? 15.78012  44.21929 -5.16573  1.000 79.84106  ? 143 GLU B OE2 1 
ATOM   6015 N N   . ALA D 2 150 ? 19.49492  47.87394 -3.23627  1.000 31.14615  ? 144 ALA B N   1 
ATOM   6016 C CA  . ALA D 2 150 ? 20.88846  47.74832 -3.63943  1.000 35.05038  ? 144 ALA B CA  1 
ATOM   6017 C C   . ALA D 2 150 ? 21.46805  46.49445 -3.00764  1.000 34.17455  ? 144 ALA B C   1 
ATOM   6018 O O   . ALA D 2 150 ? 21.03812  46.06646 -1.93271  1.000 31.96491  ? 144 ALA B O   1 
ATOM   6019 C CB  . ALA D 2 150 ? 21.71743  48.97346 -3.23843  1.000 28.39031  ? 144 ALA B CB  1 
ATOM   6020 N N   . LYS D 2 151 ? 22.43754  45.90366 -3.69318  1.000 33.03135  ? 145 LYS B N   1 
ATOM   6021 C CA  . LYS D 2 151 ? 23.16054  44.75113 -3.18416  1.000 25.56327  ? 145 LYS B CA  1 
ATOM   6022 C C   . LYS D 2 151 ? 24.53394  45.21772 -2.72172  1.000 30.09941  ? 145 LYS B C   1 
ATOM   6023 O O   . LYS D 2 151 ? 25.29687  45.78564 -3.50651  1.000 30.78009  ? 145 LYS B O   1 
ATOM   6024 C CB  . LYS D 2 151 ? 23.28482  43.65943 -4.25069  1.000 25.15922  ? 145 LYS B CB  1 
ATOM   6025 C CG  . LYS D 2 151 ? 24.05337  42.42760 -3.76996  1.000 32.99045  ? 145 LYS B CG  1 
ATOM   6026 C CD  . LYS D 2 151 ? 23.65178  41.14558 -4.52847  1.000 45.14885  ? 145 LYS B CD  1 
ATOM   6027 C CE  . LYS D 2 151 ? 24.17230  41.13148 -5.97279  1.000 51.15025  ? 145 LYS B CE  1 
ATOM   6028 N NZ  . LYS D 2 151 ? 25.66137  40.97272 -6.06684  1.000 51.68409  ? 145 LYS B NZ  1 
ATOM   6029 N N   . VAL D 2 152 ? 24.84362  44.99166 -1.45249  1.000 22.35620  ? 146 VAL B N   1 
ATOM   6030 C CA  . VAL D 2 152 ? 26.11794  45.39397 -0.87150  1.000 24.70129  ? 146 VAL B CA  1 
ATOM   6031 C C   . VAL D 2 152 ? 26.82462  44.13406 -0.41037  1.000 30.26057  ? 146 VAL B C   1 
ATOM   6032 O O   . VAL D 2 152 ? 26.36162  43.46371 0.51823   1.000 29.10714  ? 146 VAL B O   1 
ATOM   6033 C CB  . VAL D 2 152 ? 25.93611  46.37597 0.29093   1.000 31.93263  ? 146 VAL B CB  1 
ATOM   6034 C CG1 . VAL D 2 152 ? 27.27016  46.63401 0.95660   1.000 26.19242  ? 146 VAL B CG1 1 
ATOM   6035 C CG2 . VAL D 2 152 ? 25.30275  47.67627 -0.20610  1.000 27.09358  ? 146 VAL B CG2 1 
ATOM   6036 N N   . SER D 2 153 ? 27.94539  43.80848 -1.04651  1.000 25.38101  ? 147 SER B N   1 
ATOM   6037 C CA  . SER D 2 153 ? 28.70695  42.61248 -0.71763  1.000 26.33558  ? 147 SER B CA  1 
ATOM   6038 C C   . SER D 2 153 ? 30.10663  42.98837 -0.25418  1.000 30.74973  ? 147 SER B C   1 
ATOM   6039 O O   . SER D 2 153 ? 30.73617  43.89477 -0.81289  1.000 25.32218  ? 147 SER B O   1 
ATOM   6040 C CB  . SER D 2 153 ? 28.80603  41.67088 -1.92338  1.000 28.19598  ? 147 SER B CB  1 
ATOM   6041 O OG  . SER D 2 153 ? 27.54288  41.52330 -2.54886  1.000 29.60579  ? 147 SER B OG  1 
ATOM   6042 N N   . TRP D 2 154 ? 30.59313  42.26966 0.75535   1.000 24.16490  ? 148 TRP B N   1 
ATOM   6043 C CA  . TRP D 2 154 ? 31.93555  42.45153 1.28258   1.000 23.86176  ? 148 TRP B CA  1 
ATOM   6044 C C   . TRP D 2 154 ? 32.88712  41.41131 0.70952   1.000 29.25552  ? 148 TRP B C   1 
ATOM   6045 O O   . TRP D 2 154 ? 32.52876  40.24003 0.56656   1.000 28.82376  ? 148 TRP B O   1 
ATOM   6046 C CB  . TRP D 2 154 ? 31.92715  42.35229 2.80789   1.000 25.26732  ? 148 TRP B CB  1 
ATOM   6047 C CG  . TRP D 2 154 ? 31.34561  43.54743 3.45967   1.000 22.22873  ? 148 TRP B CG  1 
ATOM   6048 C CD1 . TRP D 2 154 ? 30.05289  43.72573 3.85417   1.000 26.15172  ? 148 TRP B CD1 1 
ATOM   6049 C CD2 . TRP D 2 154 ? 32.03806  44.75039 3.78530   1.000 21.70751  ? 148 TRP B CD2 1 
ATOM   6050 N NE1 . TRP D 2 154 ? 29.89435  44.97521 4.40435   1.000 24.77535  ? 148 TRP B NE1 1 
ATOM   6051 C CE2 . TRP D 2 154 ? 31.10310  45.62435 4.37428   1.000 24.46855  ? 148 TRP B CE2 1 
ATOM   6052 C CE3 . TRP D 2 154 ? 33.35738  45.18065 3.62448   1.000 21.42722  ? 148 TRP B CE3 1 
ATOM   6053 C CZ2 . TRP D 2 154 ? 31.45445  46.89251 4.83061   1.000 23.84832  ? 148 TRP B CZ2 1 
ATOM   6054 C CZ3 . TRP D 2 154 ? 33.70285  46.45125 4.07268   1.000 25.37454  ? 148 TRP B CZ3 1 
ATOM   6055 C CH2 . TRP D 2 154 ? 32.75597  47.29029 4.66085   1.000 22.13077  ? 148 TRP B CH2 1 
ATOM   6056 N N   . TYR D 2 155 ? 34.11132  41.83931 0.39837   1.000 25.53718  ? 149 TYR B N   1 
ATOM   6057 C CA  . TYR D 2 155 ? 35.17213  40.93203 -0.01535  1.000 29.67419  ? 149 TYR B CA  1 
ATOM   6058 C C   . TYR D 2 155 ? 36.39692  41.14953 0.85601   1.000 32.32646  ? 149 TYR B C   1 
ATOM   6059 O O   . TYR D 2 155 ? 36.77721  42.29013 1.13630   1.000 27.55826  ? 149 TYR B O   1 
ATOM   6060 C CB  . TYR D 2 155 ? 35.54485  41.12298 -1.49834  1.000 28.89579  ? 149 TYR B CB  1 
ATOM   6061 C CG  . TYR D 2 155 ? 34.45609  40.66912 -2.43923  1.000 33.08391  ? 149 TYR B CG  1 
ATOM   6062 C CD1 . TYR D 2 155 ? 33.41689  41.52238 -2.78014  1.000 30.61857  ? 149 TYR B CD1 1 
ATOM   6063 C CD2 . TYR D 2 155 ? 34.46063  39.38448 -2.97902  1.000 37.13694  ? 149 TYR B CD2 1 
ATOM   6064 C CE1 . TYR D 2 155 ? 32.41043  41.11864 -3.63126  1.000 32.40941  ? 149 TYR B CE1 1 
ATOM   6065 C CE2 . TYR D 2 155 ? 33.45334  38.96598 -3.83821  1.000 33.45830  ? 149 TYR B CE2 1 
ATOM   6066 C CZ  . TYR D 2 155 ? 32.43176  39.83746 -4.15869  1.000 34.15348  ? 149 TYR B CZ  1 
ATOM   6067 O OH  . TYR D 2 155 ? 31.42020  39.45568 -5.00857  1.000 47.40156  ? 149 TYR B OH  1 
ATOM   6068 N N   . VAL D 2 156 ? 37.00812  40.05182 1.28933   1.000 30.37857  ? 150 VAL B N   1 
ATOM   6069 C CA  . VAL D 2 156 ? 38.22428  40.09216 2.09667   1.000 30.79734  ? 150 VAL B CA  1 
ATOM   6070 C C   . VAL D 2 156 ? 39.25783  39.22723 1.38960   1.000 35.04100  ? 150 VAL B C   1 
ATOM   6071 O O   . VAL D 2 156 ? 39.09548  38.00258 1.30963   1.000 37.87419  ? 150 VAL B O   1 
ATOM   6072 C CB  . VAL D 2 156 ? 37.99223  39.60702 3.53678   1.000 30.84380  ? 150 VAL B CB  1 
ATOM   6073 C CG1 . VAL D 2 156 ? 39.23378  39.82519 4.36973   1.000 36.14298  ? 150 VAL B CG1 1 
ATOM   6074 C CG2 . VAL D 2 156 ? 36.80754  40.32512 4.16764   1.000 28.38226  ? 150 VAL B CG2 1 
ATOM   6075 N N   . ASP D 2 157 ? 40.32525  39.85541 0.89566   1.000 36.53454  ? 151 ASP B N   1 
ATOM   6076 C CA  . ASP D 2 157 ? 41.27386  39.21240 -0.01831  1.000 32.43378  ? 151 ASP B CA  1 
ATOM   6077 C C   . ASP D 2 157 ? 40.53993  38.45922 -1.12664  1.000 34.23610  ? 151 ASP B C   1 
ATOM   6078 O O   . ASP D 2 157 ? 40.84351  37.30246 -1.43453  1.000 40.58252  ? 151 ASP B O   1 
ATOM   6079 C CB  . ASP D 2 157 ? 42.22770  38.28411 0.73199   1.000 35.62011  ? 151 ASP B CB  1 
ATOM   6080 C CG  . ASP D 2 157 ? 43.33157  39.03677 1.45140   1.000 38.73174  ? 151 ASP B CG  1 
ATOM   6081 O OD1 . ASP D 2 157 ? 43.65045  40.17082 1.03471   1.000 36.99615  ? 151 ASP B OD1 1 
ATOM   6082 O OD2 . ASP D 2 157 ? 43.89044  38.48345 2.42320   1.000 40.66244  ? 151 ASP B OD2 1 
ATOM   6083 N N   . ASN D 2 158 ? 39.54012  39.12660 -1.70845  1.000 34.68958  ? 152 ASN B N   1 
ATOM   6084 C CA  . ASN D 2 158 ? 38.73643  38.65457 -2.84025  1.000 39.80186  ? 152 ASN B CA  1 
ATOM   6085 C C   . ASN D 2 158 ? 37.79598  37.50741 -2.50223  1.000 39.97296  ? 152 ASN B C   1 
ATOM   6086 O O   . ASN D 2 158 ? 37.19301  36.93616 -3.41160  1.000 41.98836  ? 152 ASN B O   1 
ATOM   6087 C CB  . ASN D 2 158 ? 39.60446  38.23614 -4.02870  1.000 33.15521  ? 152 ASN B CB  1 
ATOM   6088 C CG  . ASN D 2 158 ? 40.43607  39.37199 -4.55097  1.000 47.09115  ? 152 ASN B CG  1 
ATOM   6089 O OD1 . ASN D 2 158 ? 39.90099  40.34591 -5.08405  1.000 51.46646  ? 152 ASN B OD1 1 
ATOM   6090 N ND2 . ASN D 2 158 ? 41.75491  39.26794 -4.39639  1.000 49.30538  ? 152 ASN B ND2 1 
ATOM   6091 N N   . ALA D 2 159 ? 37.63425  37.15829 -1.23058  1.000 40.36382  ? 153 ALA B N   1 
ATOM   6092 C CA  . ALA D 2 159 ? 36.68558  36.12815 -0.83119  1.000 33.24204  ? 153 ALA B CA  1 
ATOM   6093 C C   . ALA D 2 159 ? 35.38826  36.79465 -0.39442  1.000 33.97718  ? 153 ALA B C   1 
ATOM   6094 O O   . ALA D 2 159 ? 35.39755  37.66070 0.48704   1.000 38.12527  ? 153 ALA B O   1 
ATOM   6095 C CB  . ALA D 2 159 ? 37.25779  35.26274 0.29216   1.000 36.89548  ? 153 ALA B CB  1 
ATOM   6096 N N   . LEU D 2 160 ? 34.28108  36.39774 -1.01343  1.000 30.72655  ? 154 LEU B N   1 
ATOM   6097 C CA  . LEU D 2 160 ? 32.98374  36.96534 -0.67881  1.000 36.79583  ? 154 LEU B CA  1 
ATOM   6098 C C   . LEU D 2 160 ? 32.57812  36.54323 0.73138   1.000 40.00236  ? 154 LEU B C   1 
ATOM   6099 O O   . LEU D 2 160 ? 32.69134  35.37179 1.09694   1.000 36.13572  ? 154 LEU B O   1 
ATOM   6100 C CB  . LEU D 2 160 ? 31.93508  36.52146 -1.70540  1.000 28.85660  ? 154 LEU B CB  1 
ATOM   6101 C CG  . LEU D 2 160 ? 30.46534  36.79145 -1.36089  1.000 40.96707  ? 154 LEU B CG  1 
ATOM   6102 C CD1 . LEU D 2 160 ? 30.18495  38.28441 -1.34332  1.000 35.78468  ? 154 LEU B CD1 1 
ATOM   6103 C CD2 . LEU D 2 160 ? 29.50684  36.07258 -2.31132  1.000 36.83920  ? 154 LEU B CD2 1 
ATOM   6104 N N   . GLN D 2 161 ? 32.12682  37.50096 1.53258   1.000 33.67759  ? 155 GLN B N   1 
ATOM   6105 C CA  . GLN D 2 161 ? 31.74063  37.24263 2.90921   1.000 32.16267  ? 155 GLN B CA  1 
ATOM   6106 C C   . GLN D 2 161 ? 30.24002  37.01627 3.00028   1.000 33.44375  ? 155 GLN B C   1 
ATOM   6107 O O   . GLN D 2 161 ? 29.46647  37.51579 2.17990   1.000 38.36315  ? 155 GLN B O   1 
ATOM   6108 C CB  . GLN D 2 161 ? 32.13560  38.41100 3.80813   1.000 36.12957  ? 155 GLN B CB  1 
ATOM   6109 C CG  . GLN D 2 161 ? 33.59086  38.77673 3.68421   1.000 32.21198  ? 155 GLN B CG  1 
ATOM   6110 C CD  . GLN D 2 161 ? 34.49000  37.70496 4.23861   1.000 37.81625  ? 155 GLN B CD  1 
ATOM   6111 O OE1 . GLN D 2 161 ? 34.50379  37.45401 5.44714   1.000 39.06075  ? 155 GLN B OE1 1 
ATOM   6112 N NE2 . GLN D 2 161 ? 35.24849  37.05626 3.35983   1.000 42.39110  ? 155 GLN B NE2 1 
ATOM   6113 N N   . SER D 2 162 ? 29.82875  36.25756 4.01068   1.000 38.56196  ? 156 SER B N   1 
ATOM   6114 C CA  . SER D 2 162 ? 28.40806  36.14153 4.30080   1.000 39.86153  ? 156 SER B CA  1 
ATOM   6115 C C   . SER D 2 162 ? 28.21843  35.92273 5.79350   1.000 39.15865  ? 156 SER B C   1 
ATOM   6116 O O   . SER D 2 162 ? 29.06475  35.32210 6.46288   1.000 34.64128  ? 156 SER B O   1 
ATOM   6117 C CB  . SER D 2 162 ? 27.74343  35.01501 3.49450   1.000 42.30884  ? 156 SER B CB  1 
ATOM   6118 O OG  . SER D 2 162 ? 28.53559  33.84069 3.49946   1.000 52.82253  ? 156 SER B OG  1 
ATOM   6119 N N   . GLY D 2 163 ? 27.10596  36.45235 6.30810   1.000 39.25730  ? 157 GLY B N   1 
ATOM   6120 C CA  . GLY D 2 163 ? 26.71530  36.26432 7.68591   1.000 45.46855  ? 157 GLY B CA  1 
ATOM   6121 C C   . GLY D 2 163 ? 27.44464  37.10111 8.71579   1.000 44.65333  ? 157 GLY B C   1 
ATOM   6122 O O   . GLY D 2 163 ? 27.09906  37.02216 9.90283   1.000 38.73861  ? 157 GLY B O   1 
ATOM   6123 N N   . ASN D 2 164 ? 28.44631  37.88936 8.32880   1.000 34.07028  ? 158 ASN B N   1 
ATOM   6124 C CA  . ASN D 2 164 ? 29.19082  38.67513 9.30737   1.000 28.45921  ? 158 ASN B CA  1 
ATOM   6125 C C   . ASN D 2 164 ? 29.02275  40.16816 9.05680   1.000 30.26768  ? 158 ASN B C   1 
ATOM   6126 O O   . ASN D 2 164 ? 29.87291  40.97045 9.45097   1.000 29.58250  ? 158 ASN B O   1 
ATOM   6127 C CB  . ASN D 2 164 ? 30.67070  38.28000 9.33039   1.000 26.20661  ? 158 ASN B CB  1 
ATOM   6128 C CG  . ASN D 2 164 ? 31.30960  38.28532 7.94461   1.000 30.00168  ? 158 ASN B CG  1 
ATOM   6129 O OD1 . ASN D 2 164 ? 30.63047  38.44715 6.93580   1.000 37.27465  ? 158 ASN B OD1 1 
ATOM   6130 N ND2 . ASN D 2 164 ? 32.61549  38.08901 7.89690   1.000 28.68809  ? 158 ASN B ND2 1 
ATOM   6131 N N   . SER D 2 165 ? 27.90618  40.55520 8.43670   1.000 26.29852  ? 159 SER B N   1 
ATOM   6132 C CA  . SER D 2 165 ? 27.64794  41.95141 8.13941   1.000 25.75054  ? 159 SER B CA  1 
ATOM   6133 C C   . SER D 2 165 ? 26.18798  42.26518 8.42224   1.000 24.33609  ? 159 SER B C   1 
ATOM   6134 O O   . SER D 2 165 ? 25.32811  41.38146 8.41239   1.000 29.74476  ? 159 SER B O   1 
ATOM   6135 C CB  . SER D 2 165 ? 28.02689  42.30194 6.68475   1.000 25.08278  ? 159 SER B CB  1 
ATOM   6136 O OG  . SER D 2 165 ? 27.18223  41.66039 5.74245   1.000 28.36133  ? 159 SER B OG  1 
ATOM   6137 N N   . GLN D 2 166 ? 25.92490  43.53645 8.70607   1.000 23.55619  ? 160 GLN B N   1 
ATOM   6138 C CA  . GLN D 2 166 ? 24.60140  44.02089 9.06487   1.000 31.82201  ? 160 GLN B CA  1 
ATOM   6139 C C   . GLN D 2 166 ? 24.36830  45.35470 8.37529   1.000 29.14720  ? 160 GLN B C   1 
ATOM   6140 O O   . GLN D 2 166 ? 25.28755  46.17077 8.28596   1.000 25.67690  ? 160 GLN B O   1 
ATOM   6141 C CB  . GLN D 2 166 ? 24.45496  44.20456 10.58525  1.000 26.80596  ? 160 GLN B CB  1 
ATOM   6142 C CG  . GLN D 2 166 ? 24.31616  42.93166 11.38488  1.000 33.89842  ? 160 GLN B CG  1 
ATOM   6143 C CD  . GLN D 2 166 ? 23.87497  43.21830 12.80566  1.000 38.87446  ? 160 GLN B CD  1 
ATOM   6144 O OE1 . GLN D 2 166 ? 24.70399  43.41402 13.69595  1.000 41.39227  ? 160 GLN B OE1 1 
ATOM   6145 N NE2 . GLN D 2 166 ? 22.55986  43.27498 13.01992  1.000 31.38442  ? 160 GLN B NE2 1 
ATOM   6146 N N   . GLU D 2 167 ? 23.13970  45.58039 7.90999   1.000 27.45967  ? 161 GLU B N   1 
ATOM   6147 C CA  . GLU D 2 167 ? 22.79188  46.77703 7.15575   1.000 29.68647  ? 161 GLU B CA  1 
ATOM   6148 C C   . GLU D 2 167 ? 21.80961  47.63546 7.92906   1.000 25.83118  ? 161 GLU B C   1 
ATOM   6149 O O   . GLU D 2 167 ? 20.98891  47.13038 8.69944   1.000 28.57853  ? 161 GLU B O   1 
ATOM   6150 C CB  . GLU D 2 167 ? 22.16814  46.43558 5.79817   1.000 26.59794  ? 161 GLU B CB  1 
ATOM   6151 C CG  . GLU D 2 167 ? 23.14639  45.81790 4.83313   1.000 28.86389  ? 161 GLU B CG  1 
ATOM   6152 C CD  . GLU D 2 167 ? 22.58797  45.72138 3.41784   1.000 37.94870  ? 161 GLU B CD  1 
ATOM   6153 O OE1 . GLU D 2 167 ? 21.40434  46.07668 3.21454   1.000 31.20684  ? 161 GLU B OE1 1 
ATOM   6154 O OE2 . GLU D 2 167 ? 23.34144  45.29597 2.51472   1.000 36.90145  ? 161 GLU B OE2 1 
ATOM   6155 N N   . SER D 2 168 ? 21.89609  48.94396 7.70455   1.000 21.14319  ? 162 SER B N   1 
ATOM   6156 C CA  . SER D 2 168 ? 20.92712  49.88453 8.24378   1.000 22.39200  ? 162 SER B CA  1 
ATOM   6157 C C   . SER D 2 168 ? 20.64540  50.95042 7.18957   1.000 22.28039  ? 162 SER B C   1 
ATOM   6158 O O   . SER D 2 168 ? 21.55695  51.40063 6.49328   1.000 20.92987  ? 162 SER B O   1 
ATOM   6159 C CB  . SER D 2 168 ? 21.43883  50.51357 9.55100   1.000 23.02976  ? 162 SER B CB  1 
ATOM   6160 O OG  . SER D 2 168 ? 20.48938  51.43213 10.06753  1.000 26.95354  ? 162 SER B OG  1 
ATOM   6161 N N   . VAL D 2 169 ? 19.38533  51.34944 7.06531   1.000 22.27141  ? 163 VAL B N   1 
ATOM   6162 C CA  . VAL D 2 169 ? 18.96481  52.25819 6.00650   1.000 27.08110  ? 163 VAL B CA  1 
ATOM   6163 C C   . VAL D 2 169 ? 18.22862  53.43208 6.62911   1.000 26.11576  ? 163 VAL B C   1 
ATOM   6164 O O   . VAL D 2 169 ? 17.47000  53.26023 7.58863   1.000 29.10682  ? 163 VAL B O   1 
ATOM   6165 C CB  . VAL D 2 169 ? 18.06470  51.54332 4.96981   1.000 31.93615  ? 163 VAL B CB  1 
ATOM   6166 C CG1 . VAL D 2 169 ? 17.83186  52.42894 3.75619   1.000 33.51507  ? 163 VAL B CG1 1 
ATOM   6167 C CG2 . VAL D 2 169 ? 18.68189  50.21681 4.54273   1.000 33.49986  ? 163 VAL B CG2 1 
ATOM   6168 N N   . THR D 2 170 ? 18.44155  54.62248 6.08134   1.000 25.24798  ? 164 THR B N   1 
ATOM   6169 C CA  . THR D 2 170 ? 17.69619  55.77915 6.54634   1.000 31.74519  ? 164 THR B CA  1 
ATOM   6170 C C   . THR D 2 170 ? 16.33398  55.83160 5.87275   1.000 29.69668  ? 164 THR B C   1 
ATOM   6171 O O   . THR D 2 170 ? 16.07387  55.15402 4.87440   1.000 32.98289  ? 164 THR B O   1 
ATOM   6172 C CB  . THR D 2 170 ? 18.44543  57.07611 6.25485   1.000 33.45093  ? 164 THR B CB  1 
ATOM   6173 O OG1 . THR D 2 170 ? 18.56025  57.24116 4.82919   1.000 33.35478  ? 164 THR B OG1 1 
ATOM   6174 C CG2 . THR D 2 170 ? 19.81372  57.02071 6.87630   1.000 31.65036  ? 164 THR B CG2 1 
ATOM   6175 N N   . GLU D 2 171 ? 15.44929  56.63304 6.44691   1.000 29.68979  ? 165 GLU B N   1 
ATOM   6176 C CA  . GLU D 2 171 ? 14.19427  56.87593 5.76725   1.000 41.35299  ? 165 GLU B CA  1 
ATOM   6177 C C   . GLU D 2 171 ? 14.41807  57.88103 4.64314   1.000 32.75045  ? 165 GLU B C   1 
ATOM   6178 O O   . GLU D 2 171 ? 15.47147  58.52519 4.54257   1.000 26.24520  ? 165 GLU B O   1 
ATOM   6179 C CB  . GLU D 2 171 ? 13.13439  57.35764 6.75609   1.000 42.86580  ? 165 GLU B CB  1 
ATOM   6180 C CG  . GLU D 2 171 ? 13.65616  58.33405 7.80037   1.000 55.88874  ? 165 GLU B CG  1 
ATOM   6181 C CD  . GLU D 2 171 ? 13.37589  59.79044 7.45684   1.000 55.17416  ? 165 GLU B CD  1 
ATOM   6182 O OE1 . GLU D 2 171 ? 12.33876  60.07609 6.81646   1.000 63.55012  ? 165 GLU B OE1 1 
ATOM   6183 O OE2 . GLU D 2 171 ? 14.19603  60.65372 7.83537   1.000 62.27714  ? 165 GLU B OE2 1 
ATOM   6184 N N   . GLN D 2 172 ? 13.41692  58.00198 3.77836   1.000 35.40707  ? 166 GLN B N   1 
ATOM   6185 C CA  . GLN D 2 172 ? 13.54506  58.88653 2.63072   1.000 34.91069  ? 166 GLN B CA  1 
ATOM   6186 C C   . GLN D 2 172 ? 13.74781  60.32536 3.09647   1.000 34.54896  ? 166 GLN B C   1 
ATOM   6187 O O   . GLN D 2 172 ? 12.97480  60.84737 3.90631   1.000 33.54808  ? 166 GLN B O   1 
ATOM   6188 C CB  . GLN D 2 172 ? 12.31073  58.76826 1.72846   1.000 30.77411  ? 166 GLN B CB  1 
ATOM   6189 C CG  . GLN D 2 172 ? 12.66885  58.63752 0.25191   1.000 35.26203  ? 166 GLN B CG  1 
ATOM   6190 C CD  . GLN D 2 172 ? 11.46913  58.70238 -0.68937  1.000 38.64012  ? 166 GLN B CD  1 
ATOM   6191 O OE1 . GLN D 2 172 ? 10.31570  58.60409 -0.27351  1.000 40.42199  ? 166 GLN B OE1 1 
ATOM   6192 N NE2 . GLN D 2 172 ? 11.74996  58.87012 -1.96883  1.000 34.72400  ? 166 GLN B NE2 1 
ATOM   6193 N N   . ASP D 2 173 ? 14.80133  60.95946 2.58758   1.000 32.86767  ? 167 ASP B N   1 
ATOM   6194 C CA  . ASP D 2 173 ? 15.13946  62.31495 3.00316   1.000 32.68990  ? 167 ASP B CA  1 
ATOM   6195 C C   . ASP D 2 173 ? 14.01253  63.28260 2.64822   1.000 45.14782  ? 167 ASP B C   1 
ATOM   6196 O O   . ASP D 2 173 ? 13.32220  63.12662 1.63645   1.000 40.77050  ? 167 ASP B O   1 
ATOM   6197 C CB  . ASP D 2 173 ? 16.45128  62.75409 2.34713   1.000 31.70511  ? 167 ASP B CB  1 
ATOM   6198 C CG  . ASP D 2 173 ? 16.94803  64.10346 2.85765   1.000 44.58574  ? 167 ASP B CG  1 
ATOM   6199 O OD1 . ASP D 2 173 ? 17.43252  64.16798 4.00993   1.000 57.50956  ? 167 ASP B OD1 1 
ATOM   6200 O OD2 . ASP D 2 173 ? 16.86164  65.09829 2.10220   1.000 45.88123  ? 167 ASP B OD2 1 
ATOM   6201 N N   . SER D 2 174 ? 13.82276  64.29111 3.50539   1.000 51.24755  ? 168 SER B N   1 
ATOM   6202 C CA  . SER D 2 174 ? 12.74899  65.26063 3.30187   1.000 54.95329  ? 168 SER B CA  1 
ATOM   6203 C C   . SER D 2 174 ? 13.05355  66.26093 2.18824   1.000 53.34780  ? 168 SER B C   1 
ATOM   6204 O O   . SER D 2 174 ? 12.11959  66.82833 1.61193   1.000 49.82091  ? 168 SER B O   1 
ATOM   6205 C CB  . SER D 2 174 ? 12.47405  66.00455 4.60848   1.000 50.46312  ? 168 SER B CB  1 
ATOM   6206 O OG  . SER D 2 174 ? 13.66746  66.57773 5.11329   1.000 55.31373  ? 168 SER B OG  1 
ATOM   6207 N N   . LYS D 2 175 ? 14.32932  66.48627 1.86894   1.000 50.50607  ? 169 LYS B N   1 
ATOM   6208 C CA  . LYS D 2 175 ? 14.71712  67.46309 0.85271   1.000 50.25709  ? 169 LYS B CA  1 
ATOM   6209 C C   . LYS D 2 175 ? 14.80071  66.84605 -0.54355  1.000 49.04471  ? 169 LYS B C   1 
ATOM   6210 O O   . LYS D 2 175 ? 14.11169  67.29615 -1.46424  1.000 59.14000  ? 169 LYS B O   1 
ATOM   6211 C CB  . LYS D 2 175 ? 16.05787  68.10379 1.22620   1.000 48.42174  ? 169 LYS B CB  1 
ATOM   6212 C CG  . LYS D 2 175 ? 16.15191  68.49140 2.68331   1.000 69.96854  ? 169 LYS B CG  1 
ATOM   6213 C CD  . LYS D 2 175 ? 17.55391  68.93582 3.07635   1.000 69.03902  ? 169 LYS B CD  1 
ATOM   6214 C CE  . LYS D 2 175 ? 17.56203  69.33619 4.53947   1.000 64.46840  ? 169 LYS B CE  1 
ATOM   6215 N NZ  . LYS D 2 175 ? 16.72966  68.37910 5.33070   1.000 74.07906  ? 169 LYS B NZ  1 
ATOM   6216 N N   . ASP D 2 176 ? 15.64755  65.82493 -0.72103  1.000 44.48140  ? 170 ASP B N   1 
ATOM   6217 C CA  . ASP D 2 176 ? 15.91892  65.27181 -2.04553  1.000 33.14223  ? 170 ASP B CA  1 
ATOM   6218 C C   . ASP D 2 176 ? 15.34811  63.87509 -2.26353  1.000 39.41040  ? 170 ASP B C   1 
ATOM   6219 O O   . ASP D 2 176 ? 15.59450  63.28519 -3.32398  1.000 39.18735  ? 170 ASP B O   1 
ATOM   6220 C CB  . ASP D 2 176 ? 17.43135  65.26843 -2.33394  1.000 34.04300  ? 170 ASP B CB  1 
ATOM   6221 C CG  . ASP D 2 176 ? 18.23084  64.40326 -1.36623  1.000 46.85600  ? 170 ASP B CG  1 
ATOM   6222 O OD1 . ASP D 2 176 ? 17.64104  63.75617 -0.47406  1.000 45.33737  ? 170 ASP B OD1 1 
ATOM   6223 O OD2 . ASP D 2 176 ? 19.47530  64.37895 -1.49371  1.000 55.25483  ? 170 ASP B OD2 1 
ATOM   6224 N N   . SER D 2 177 ? 14.59870  63.33143 -1.29978  1.000 31.40759  ? 171 SER B N   1 
ATOM   6225 C CA  . SER D 2 177 ? 13.90622  62.04963 -1.45271  1.000 37.29329  ? 171 SER B CA  1 
ATOM   6226 C C   . SER D 2 177 ? 14.86241  60.89513 -1.74872  1.000 33.73345  ? 171 SER B C   1 
ATOM   6227 O O   . SER D 2 177 ? 14.48012  59.90153 -2.37588  1.000 33.51236  ? 171 SER B O   1 
ATOM   6228 C CB  . SER D 2 177 ? 12.82414  62.13031 -2.53322  1.000 36.91676  ? 171 SER B CB  1 
ATOM   6229 O OG  . SER D 2 177 ? 11.78164  62.98228 -2.10559  1.000 47.62174  ? 171 SER B OG  1 
ATOM   6230 N N   . THR D 2 178 ? 16.10196  60.99986 -1.29007  1.000 31.96957  ? 172 THR B N   1 
ATOM   6231 C CA  . THR D 2 178 ? 17.04491  59.90024 -1.38169  1.000 29.19195  ? 172 THR B CA  1 
ATOM   6232 C C   . THR D 2 178 ? 17.10705  59.11327 -0.07292  1.000 34.39932  ? 172 THR B C   1 
ATOM   6233 O O   . THR D 2 178 ? 16.55412  59.50128 0.96404   1.000 31.80497  ? 172 THR B O   1 
ATOM   6234 C CB  . THR D 2 178 ? 18.44272  60.40773 -1.72402  1.000 32.67731  ? 172 THR B CB  1 
ATOM   6235 O OG1 . THR D 2 178 ? 18.87255  61.32648 -0.70514  1.000 30.35777  ? 172 THR B OG1 1 
ATOM   6236 C CG2 . THR D 2 178 ? 18.44616  61.08923 -3.09494  1.000 30.16413  ? 172 THR B CG2 1 
ATOM   6237 N N   . TYR D 2 179 ? 17.83715  58.00728 -0.14251  1.000 26.50317  ? 173 TYR B N   1 
ATOM   6238 C CA  . TYR D 2 179 ? 18.13985  57.13213 0.97349   1.000 29.18311  ? 173 TYR B CA  1 
ATOM   6239 C C   . TYR D 2 179 ? 19.63888  57.14468 1.23153   1.000 33.97879  ? 173 TYR B C   1 
ATOM   6240 O O   . TYR D 2 179 ? 20.43745  57.50172 0.35968   1.000 26.02127  ? 173 TYR B O   1 
ATOM   6241 C CB  . TYR D 2 179 ? 17.69719  55.69281 0.68549   1.000 25.13218  ? 173 TYR B CB  1 
ATOM   6242 C CG  . TYR D 2 179 ? 16.21423  55.52621 0.47661   1.000 27.84193  ? 173 TYR B CG  1 
ATOM   6243 C CD1 . TYR D 2 179 ? 15.36510  55.34716 1.56483   1.000 28.61106  ? 173 TYR B CD1 1 
ATOM   6244 C CD2 . TYR D 2 179 ? 15.65939  55.53806 -0.80499  1.000 31.34810  ? 173 TYR B CD2 1 
ATOM   6245 C CE1 . TYR D 2 179 ? 14.00685  55.18995 1.39744   1.000 34.67873  ? 173 TYR B CE1 1 
ATOM   6246 C CE2 . TYR D 2 179 ? 14.28577  55.37567 -0.99126  1.000 33.03159  ? 173 TYR B CE2 1 
ATOM   6247 C CZ  . TYR D 2 179 ? 13.46885  55.20235 0.12158   1.000 39.77918  ? 173 TYR B CZ  1 
ATOM   6248 O OH  . TYR D 2 179 ? 12.11166  55.04521 -0.01279  1.000 43.87526  ? 173 TYR B OH  1 
ATOM   6249 N N   . SER D 2 180 ? 20.01836  56.75484 2.44899   1.000 30.78068  ? 174 SER B N   1 
ATOM   6250 C CA  . SER D 2 180 ? 21.40192  56.43116 2.75184   1.000 17.59852  ? 174 SER B CA  1 
ATOM   6251 C C   . SER D 2 180 ? 21.44618  55.07850 3.44698   1.000 22.59579  ? 174 SER B C   1 
ATOM   6252 O O   . SER D 2 180 ? 20.49619  54.66772 4.12113   1.000 25.63351  ? 174 SER B O   1 
ATOM   6253 C CB  . SER D 2 180 ? 22.06308  57.49517 3.59507   1.000 26.70731  ? 174 SER B CB  1 
ATOM   6254 O OG  . SER D 2 180 ? 22.18657  58.68501 2.84569   1.000 22.63348  ? 174 SER B OG  1 
ATOM   6255 N N   . LEU D 2 181 ? 22.54679  54.37159 3.25263   1.000 21.18565  ? 175 LEU B N   1 
ATOM   6256 C CA  . LEU D 2 181 ? 22.64531  53.01118 3.74423   1.000 24.85467  ? 175 LEU B CA  1 
ATOM   6257 C C   . LEU D 2 181 ? 24.03109  52.78422 4.32026   1.000 23.20100  ? 175 LEU B C   1 
ATOM   6258 O O   . LEU D 2 181 ? 25.03370  53.20285 3.73005   1.000 19.91798  ? 175 LEU B O   1 
ATOM   6259 C CB  . LEU D 2 181 ? 22.35042  52.00879 2.61776   1.000 23.96440  ? 175 LEU B CB  1 
ATOM   6260 C CG  . LEU D 2 181 ? 22.35685  50.51913 2.97504   1.000 23.36161  ? 175 LEU B CG  1 
ATOM   6261 C CD1 . LEU D 2 181 ? 21.40872  49.76642 2.06181   1.000 28.91289  ? 175 LEU B CD1 1 
ATOM   6262 C CD2 . LEU D 2 181 ? 23.75958  49.94495 2.87136   1.000 24.37484  ? 175 LEU B CD2 1 
ATOM   6263 N N   . SER D 2 182 ? 24.09400  52.10284 5.46626   1.000 19.55133  ? 176 SER B N   1 
ATOM   6264 C CA  . SER D 2 182 ? 25.37406  51.65757 5.99559   1.000 19.33492  ? 176 SER B CA  1 
ATOM   6265 C C   . SER D 2 182 ? 25.42238  50.13968 5.97446   1.000 23.99698  ? 176 SER B C   1 
ATOM   6266 O O   . SER D 2 182 ? 24.41611  49.47173 6.22753   1.000 26.43560  ? 176 SER B O   1 
ATOM   6267 C CB  . SER D 2 182 ? 25.62788  52.16926 7.43903   1.000 23.55229  ? 176 SER B CB  1 
ATOM   6268 O OG  . SER D 2 182 ? 24.73284  51.55465 8.35715   1.000 23.19274  ? 176 SER B OG  1 
ATOM   6269 N N   . SER D 2 183 ? 26.59749  49.59529 5.68814   1.000 24.08318  ? 177 SER B N   1 
ATOM   6270 C CA  . SER D 2 183 ? 26.86427  48.18579 5.91184   1.000 22.94878  ? 177 SER B CA  1 
ATOM   6271 C C   . SER D 2 183 ? 28.09958  48.05309 6.78491   1.000 23.62996  ? 177 SER B C   1 
ATOM   6272 O O   . SER D 2 183 ? 29.12012  48.69859 6.52457   1.000 25.50527  ? 177 SER B O   1 
ATOM   6273 C CB  . SER D 2 183 ? 27.06908  47.43821 4.60299   1.000 24.58246  ? 177 SER B CB  1 
ATOM   6274 O OG  . SER D 2 183 ? 27.30792  46.07265 4.89600   1.000 27.89195  ? 177 SER B OG  1 
ATOM   6275 N N   . THR D 2 184 ? 28.00762  47.22201 7.82224   1.000 23.60818  ? 178 THR B N   1 
ATOM   6276 C CA  . THR D 2 184 ? 29.07877  47.07831 8.79898   1.000 18.65444  ? 178 THR B CA  1 
ATOM   6277 C C   . THR D 2 184 ? 29.50550  45.61809 8.85482   1.000 27.37192  ? 178 THR B C   1 
ATOM   6278 O O   . THR D 2 184 ? 28.69050  44.74200 9.16795   1.000 20.51461  ? 178 THR B O   1 
ATOM   6279 C CB  . THR D 2 184 ? 28.63650  47.55066 10.18622  1.000 20.05969  ? 178 THR B CB  1 
ATOM   6280 O OG1 . THR D 2 184 ? 27.99069  48.82884 10.09028  1.000 27.42897  ? 178 THR B OG1 1 
ATOM   6281 C CG2 . THR D 2 184 ? 29.83022  47.64310 11.11680  1.000 23.33959  ? 178 THR B CG2 1 
ATOM   6282 N N   . LEU D 2 185 ? 30.77425  45.36971 8.54551   1.000 24.21997  ? 179 LEU B N   1 
ATOM   6283 C CA  . LEU D 2 185 ? 31.38825  44.05315 8.59966   1.000 25.19029  ? 179 LEU B CA  1 
ATOM   6284 C C   . LEU D 2 185 ? 32.12895  43.92093 9.92152   1.000 28.68417  ? 179 LEU B C   1 
ATOM   6285 O O   . LEU D 2 185 ? 32.95850  44.77257 10.25165  1.000 24.89626  ? 179 LEU B O   1 
ATOM   6286 C CB  . LEU D 2 185 ? 32.36399  43.87235 7.43795   1.000 20.38949  ? 179 LEU B CB  1 
ATOM   6287 C CG  . LEU D 2 185 ? 33.25498  42.63388 7.46139   1.000 26.08490  ? 179 LEU B CG  1 
ATOM   6288 C CD1 . LEU D 2 185 ? 32.40333  41.40792 7.19032   1.000 30.56940  ? 179 LEU B CD1 1 
ATOM   6289 C CD2 . LEU D 2 185 ? 34.38501  42.72755 6.45082   1.000 27.62703  ? 179 LEU B CD2 1 
ATOM   6290 N N   . THR D 2 186 ? 31.83618  42.86526 10.67586  1.000 27.59118  ? 180 THR B N   1 
ATOM   6291 C CA  . THR D 2 186 ? 32.43172  42.67911 11.99709  1.000 28.70395  ? 180 THR B CA  1 
ATOM   6292 C C   . THR D 2 186 ? 33.31596  41.43953 11.99216  1.000 28.25074  ? 180 THR B C   1 
ATOM   6293 O O   . THR D 2 186 ? 32.83803  40.32846 11.73489  1.000 32.08665  ? 180 THR B O   1 
ATOM   6294 C CB  . THR D 2 186 ? 31.36021  42.57687 13.08133  1.000 33.65051  ? 180 THR B CB  1 
ATOM   6295 O OG1 . THR D 2 186 ? 30.58476  43.78064 13.08942  1.000 35.68363  ? 180 THR B OG1 1 
ATOM   6296 C CG2 . THR D 2 186 ? 32.00811  42.40320 14.45187  1.000 36.02826  ? 180 THR B CG2 1 
ATOM   6297 N N   . LEU D 2 187 ? 34.60078  41.64275 12.26236  1.000 28.37929  ? 181 LEU B N   1 
ATOM   6298 C CA  . LEU D 2 187 ? 35.58893  40.58432 12.36084  1.000 32.23579  ? 181 LEU B CA  1 
ATOM   6299 C C   . LEU D 2 187 ? 36.27374  40.67074 13.71339  1.000 33.64522  ? 181 LEU B C   1 
ATOM   6300 O O   . LEU D 2 187 ? 36.29762  41.72583 14.34992  1.000 25.27919  ? 181 LEU B O   1 
ATOM   6301 C CB  . LEU D 2 187 ? 36.65066  40.69686 11.26444  1.000 32.21262  ? 181 LEU B CB  1 
ATOM   6302 C CG  . LEU D 2 187 ? 36.11495  40.72746 9.84284   1.000 35.48746  ? 181 LEU B CG  1 
ATOM   6303 C CD1 . LEU D 2 187 ? 37.24732  40.98272 8.84996   1.000 35.66400  ? 181 LEU B CD1 1 
ATOM   6304 C CD2 . LEU D 2 187 ? 35.43303  39.40412 9.56450   1.000 33.57562  ? 181 LEU B CD2 1 
ATOM   6305 N N   . SER D 2 188 ? 36.84163  39.54835 14.14183  1.000 35.90411  ? 182 SER B N   1 
ATOM   6306 C CA  . SER D 2 188 ? 37.77700  39.58537 15.25050  1.000 32.80647  ? 182 SER B CA  1 
ATOM   6307 C C   . SER D 2 188 ? 39.05279  40.28870 14.81220  1.000 33.02810  ? 182 SER B C   1 
ATOM   6308 O O   . SER D 2 188 ? 39.42273  40.26274 13.63387  1.000 41.67291  ? 182 SER B O   1 
ATOM   6309 C CB  . SER D 2 188 ? 38.09947  38.17048 15.72205  1.000 37.00968  ? 182 SER B CB  1 
ATOM   6310 O OG  . SER D 2 188 ? 38.78375  37.45405 14.70546  1.000 35.43117  ? 182 SER B OG  1 
ATOM   6311 N N   . LYS D 2 189 ? 39.72903  40.92850 15.76947  1.000 28.22453  ? 183 LYS B N   1 
ATOM   6312 C CA  . LYS D 2 189 ? 41.02364  41.53161 15.46499  1.000 31.49941  ? 183 LYS B CA  1 
ATOM   6313 C C   . LYS D 2 189 ? 41.94980  40.52114 14.80150  1.000 42.14914  ? 183 LYS B C   1 
ATOM   6314 O O   . LYS D 2 189 ? 42.64985  40.84638 13.83071  1.000 37.98096  ? 183 LYS B O   1 
ATOM   6315 C CB  . LYS D 2 189 ? 41.66610  42.09148 16.73613  1.000 35.03327  ? 183 LYS B CB  1 
ATOM   6316 C CG  . LYS D 2 189 ? 43.07031  42.63685 16.51542  1.000 41.64743  ? 183 LYS B CG  1 
ATOM   6317 C CD  . LYS D 2 189 ? 43.78478  42.97678 17.81872  1.000 46.41191  ? 183 LYS B CD  1 
ATOM   6318 C CE  . LYS D 2 189 ? 45.17634  43.53210 17.53632  1.000 48.94097  ? 183 LYS B CE  1 
ATOM   6319 N NZ  . LYS D 2 189 ? 45.89048  43.99149 18.75735  1.000 60.92964  ? 183 LYS B NZ  1 
ATOM   6320 N N   . ALA D 2 190 ? 41.92939  39.27316 15.28429  1.000 37.03751  ? 184 ALA B N   1 
ATOM   6321 C CA  . ALA D 2 190 ? 42.81279  38.24613 14.73911  1.000 33.96008  ? 184 ALA B CA  1 
ATOM   6322 C C   . ALA D 2 190 ? 42.51378  37.98185 13.27021  1.000 32.37452  ? 184 ALA B C   1 
ATOM   6323 O O   . ALA D 2 190 ? 43.42897  37.93777 12.44140  1.000 37.38572  ? 184 ALA B O   1 
ATOM   6324 C CB  . ALA D 2 190 ? 42.69017  36.95845 15.55437  1.000 43.66931  ? 184 ALA B CB  1 
ATOM   6325 N N   . ASP D 2 191 ? 41.23444  37.79498 12.92595  1.000 36.28736  ? 185 ASP B N   1 
ATOM   6326 C CA  . ASP D 2 191 ? 40.87469  37.61131 11.51965  1.000 39.07008  ? 185 ASP B CA  1 
ATOM   6327 C C   . ASP D 2 191 ? 41.18234  38.85887 10.69883  1.000 37.74062  ? 185 ASP B C   1 
ATOM   6328 O O   . ASP D 2 191 ? 41.66481  38.76046 9.56522   1.000 40.27436  ? 185 ASP B O   1 
ATOM   6329 C CB  . ASP D 2 191 ? 39.39672  37.24701 11.38318  1.000 41.11596  ? 185 ASP B CB  1 
ATOM   6330 C CG  . ASP D 2 191 ? 39.09658  35.83212 11.84249  1.000 55.36965  ? 185 ASP B CG  1 
ATOM   6331 O OD1 . ASP D 2 191 ? 39.83028  34.89925 11.44443  1.000 56.33755  ? 185 ASP B OD1 1 
ATOM   6332 O OD2 . ASP D 2 191 ? 38.12731  35.65843 12.61181  1.000 53.67910  ? 185 ASP B OD2 1 
ATOM   6333 N N   . TYR D 2 192 ? 40.91603  40.04292 11.25294  1.000 37.26545  ? 186 TYR B N   1 
ATOM   6334 C CA  . TYR D 2 192 ? 41.17385  41.26576 10.49969  1.000 38.93949  ? 186 TYR B CA  1 
ATOM   6335 C C   . TYR D 2 192 ? 42.65257  41.39606 10.15290  1.000 37.18673  ? 186 TYR B C   1 
ATOM   6336 O O   . TYR D 2 192 ? 43.00473  41.78237 9.03079   1.000 34.40110  ? 186 TYR B O   1 
ATOM   6337 C CB  . TYR D 2 192 ? 40.68822  42.49043 11.27905  1.000 32.26528  ? 186 TYR B CB  1 
ATOM   6338 C CG  . TYR D 2 192 ? 41.05357  43.80662 10.61336  1.000 30.74116  ? 186 TYR B CG  1 
ATOM   6339 C CD1 . TYR D 2 192 ? 40.38331  44.25106 9.47342   1.000 30.14048  ? 186 TYR B CD1 1 
ATOM   6340 C CD2 . TYR D 2 192 ? 42.06934  44.59244 11.11335  1.000 30.47423  ? 186 TYR B CD2 1 
ATOM   6341 C CE1 . TYR D 2 192 ? 40.73314  45.44983 8.85087   1.000 27.93819  ? 186 TYR B CE1 1 
ATOM   6342 C CE2 . TYR D 2 192 ? 42.41556  45.79227 10.50726  1.000 31.37038  ? 186 TYR B CE2 1 
ATOM   6343 C CZ  . TYR D 2 192 ? 41.74172  46.21653 9.38106   1.000 30.63693  ? 186 TYR B CZ  1 
ATOM   6344 O OH  . TYR D 2 192 ? 42.10363  47.41455 8.80207   1.000 28.18725  ? 186 TYR B OH  1 
ATOM   6345 N N   . GLU D 2 193 ? 43.53229  41.05271 11.08951  1.000 36.84331  ? 187 GLU B N   1 
ATOM   6346 C CA  . GLU D 2 193 ? 44.96777  41.17267 10.86759  1.000 40.26669  ? 187 GLU B CA  1 
ATOM   6347 C C   . GLU D 2 193 ? 45.54571  40.05651 10.00908  1.000 36.78399  ? 187 GLU B C   1 
ATOM   6348 O O   . GLU D 2 193 ? 46.74675  40.08425 9.71676   1.000 41.48705  ? 187 GLU B O   1 
ATOM   6349 C CB  . GLU D 2 193 ? 45.69673  41.22002 12.20732  1.000 45.82094  ? 187 GLU B CB  1 
ATOM   6350 C CG  . GLU D 2 193 ? 45.55762  42.54595 12.91705  1.000 45.73714  ? 187 GLU B CG  1 
ATOM   6351 C CD  . GLU D 2 193 ? 46.44485  42.64143 14.14090  1.000 64.44296  ? 187 GLU B CD  1 
ATOM   6352 O OE1 . GLU D 2 193 ? 46.25102  41.84157 15.08058  1.000 57.33311  ? 187 GLU B OE1 1 
ATOM   6353 O OE2 . GLU D 2 193 ? 47.34679  43.50729 14.15573  1.000 75.29595  ? 187 GLU B OE2 1 
ATOM   6354 N N   . LYS D 2 194 ? 44.73811  39.08081 9.60019   1.000 41.03903  ? 188 LYS B N   1 
ATOM   6355 C CA  . LYS D 2 194 ? 45.22304  38.00675 8.74219   1.000 42.82455  ? 188 LYS B CA  1 
ATOM   6356 C C   . LYS D 2 194 ? 45.05955  38.30351 7.25776   1.000 46.07116  ? 188 LYS B C   1 
ATOM   6357 O O   . LYS D 2 194 ? 45.56889  37.53896 6.43160   1.000 46.91161  ? 188 LYS B O   1 
ATOM   6358 C CB  . LYS D 2 194 ? 44.50654  36.68996 9.06896   1.000 42.90080  ? 188 LYS B CB  1 
ATOM   6359 C CG  . LYS D 2 194 ? 45.02949  36.00129 10.32083  1.000 55.68869  ? 188 LYS B CG  1 
ATOM   6360 C CD  . LYS D 2 194 ? 44.84438  34.49106 10.24893  1.000 61.88808  ? 188 LYS B CD  1 
ATOM   6361 C CE  . LYS D 2 194 ? 43.80838  33.99087 11.24497  1.000 56.85268  ? 188 LYS B CE  1 
ATOM   6362 N NZ  . LYS D 2 194 ? 42.44263  34.54896 10.98622  1.000 60.39108  ? 188 LYS B NZ  1 
ATOM   6363 N N   . HIS D 2 195 ? 44.36791  39.38029 6.89135   1.000 40.25916  ? 189 HIS B N   1 
ATOM   6364 C CA  . HIS D 2 195 ? 44.11579  39.67522 5.48983   1.000 38.45666  ? 189 HIS B CA  1 
ATOM   6365 C C   . HIS D 2 195 ? 44.50826  41.11361 5.17953   1.000 36.68627  ? 189 HIS B C   1 
ATOM   6366 O O   . HIS D 2 195 ? 44.66468  41.94577 6.07508   1.000 35.53156  ? 189 HIS B O   1 
ATOM   6367 C CB  . HIS D 2 195 ? 42.64844  39.42097 5.13082   1.000 37.39844  ? 189 HIS B CB  1 
ATOM   6368 C CG  . HIS D 2 195 ? 42.20839  38.01158 5.37467   1.000 46.54311  ? 189 HIS B CG  1 
ATOM   6369 N ND1 . HIS D 2 195 ? 41.56965  37.62011 6.53215   1.000 44.59765  ? 189 HIS B ND1 1 
ATOM   6370 C CD2 . HIS D 2 195 ? 42.33357  36.89536 4.61763   1.000 42.13611  ? 189 HIS B CD2 1 
ATOM   6371 C CE1 . HIS D 2 195 ? 41.31270  36.32522 6.47485   1.000 47.38479  ? 189 HIS B CE1 1 
ATOM   6372 N NE2 . HIS D 2 195 ? 41.76787  35.86088 5.32436   1.000 51.29802  ? 189 HIS B NE2 1 
ATOM   6373 N N   . LYS D 2 196 ? 44.65365  41.40202 3.88851   1.000 31.52608  ? 190 LYS B N   1 
ATOM   6374 C CA  . LYS D 2 196 ? 45.15144  42.69363 3.43195   1.000 36.46142  ? 190 LYS B CA  1 
ATOM   6375 C C   . LYS D 2 196 ? 44.08038  43.57175 2.80170   1.000 31.58931  ? 190 LYS B C   1 
ATOM   6376 O O   . LYS D 2 196 ? 43.91649  44.72446 3.21143   1.000 25.69653  ? 190 LYS B O   1 
ATOM   6377 C CB  . LYS D 2 196 ? 46.29657  42.48219 2.43466   1.000 31.19891  ? 190 LYS B CB  1 
ATOM   6378 C CG  . LYS D 2 196 ? 47.45024  43.45806 2.59450   1.000 49.66538  ? 190 LYS B CG  1 
ATOM   6379 C CD  . LYS D 2 196 ? 47.40291  44.54199 1.53246   1.000 52.18182  ? 190 LYS B CD  1 
ATOM   6380 C CE  . LYS D 2 196 ? 48.76632  45.21002 1.37078   1.000 63.12081  ? 190 LYS B CE  1 
ATOM   6381 N NZ  . LYS D 2 196 ? 48.77691  46.25878 0.30971   1.000 64.26021  ? 190 LYS B NZ  1 
ATOM   6382 N N   . VAL D 2 197 ? 43.34313  43.06072 1.81688   1.000 25.97988  ? 191 VAL B N   1 
ATOM   6383 C CA  . VAL D 2 197 ? 42.45291  43.86628 0.98314   1.000 24.47895  ? 191 VAL B CA  1 
ATOM   6384 C C   . VAL D 2 197 ? 41.00841  43.70641 1.46293   1.000 27.53863  ? 191 VAL B C   1 
ATOM   6385 O O   . VAL D 2 197 ? 40.46048  42.59485 1.47272   1.000 27.39590  ? 191 VAL B O   1 
ATOM   6386 C CB  . VAL D 2 197 ? 42.59940  43.48003 -0.50032  1.000 28.74629  ? 191 VAL B CB  1 
ATOM   6387 C CG1 . VAL D 2 197 ? 41.67918  44.30664 -1.39157  1.000 29.08571  ? 191 VAL B CG1 1 
ATOM   6388 C CG2 . VAL D 2 197 ? 44.06747  43.62999 -0.93510  1.000 31.20427  ? 191 VAL B CG2 1 
ATOM   6389 N N   . TYR D 2 198 ? 40.38539  44.82594 1.83808   1.000 24.00292  ? 192 TYR B N   1 
ATOM   6390 C CA  . TYR D 2 198 ? 38.98083  44.89142 2.23310   1.000 20.96371  ? 192 TYR B CA  1 
ATOM   6391 C C   . TYR D 2 198 ? 38.21692  45.70712 1.20186   1.000 25.68363  ? 192 TYR B C   1 
ATOM   6392 O O   . TYR D 2 198 ? 38.63978  46.81112 0.85479   1.000 23.49363  ? 192 TYR B O   1 
ATOM   6393 C CB  . TYR D 2 198 ? 38.84086  45.50501 3.63070   1.000 22.59704  ? 192 TYR B CB  1 
ATOM   6394 C CG  . TYR D 2 198 ? 39.39175  44.55972 4.66201   1.000 23.65875  ? 192 TYR B CG  1 
ATOM   6395 C CD1 . TYR D 2 198 ? 40.76037  44.51481 4.92330   1.000 26.12903  ? 192 TYR B CD1 1 
ATOM   6396 C CD2 . TYR D 2 198 ? 38.56393  43.65930 5.31840   1.000 28.12179  ? 192 TYR B CD2 1 
ATOM   6397 C CE1 . TYR D 2 198 ? 41.28710  43.62974 5.83925   1.000 28.57237  ? 192 TYR B CE1 1 
ATOM   6398 C CE2 . TYR D 2 198 ? 39.08432  42.75793 6.23877   1.000 30.02825  ? 192 TYR B CE2 1 
ATOM   6399 C CZ  . TYR D 2 198 ? 40.44744  42.75267 6.49471   1.000 28.80895  ? 192 TYR B CZ  1 
ATOM   6400 O OH  . TYR D 2 198 ? 40.97607  41.86684 7.40520   1.000 33.31434  ? 192 TYR B OH  1 
ATOM   6401 N N   . ALA D 2 199 ? 37.10997  45.16209 0.69871   1.000 19.92209  ? 193 ALA B N   1 
ATOM   6402 C CA  . ALA D 2 199 ? 36.35004  45.82864 -0.34733  1.000 21.22162  ? 193 ALA B CA  1 
ATOM   6403 C C   . ALA D 2 199 ? 34.86508  45.69000 -0.09110  1.000 22.90536  ? 193 ALA B C   1 
ATOM   6404 O O   . ALA D 2 199 ? 34.38942  44.62868 0.32287   1.000 22.72016  ? 193 ALA B O   1 
ATOM   6405 C CB  . ALA D 2 199 ? 36.67839  45.25441 -1.73966  1.000 22.33612  ? 193 ALA B CB  1 
ATOM   6406 N N   . CYS D 2 200 ? 34.13336  46.76190 -0.35666  1.000 19.75973  ? 194 CYS B N   1 
ATOM   6407 C CA  A CYS D 2 200 ? 32.67945  46.77630 -0.35882  0.554 20.50070  ? 194 CYS B CA  1 
ATOM   6408 C CA  B CYS D 2 200 ? 32.68042  46.70094 -0.38278  0.446 20.54898  ? 194 CYS B CA  1 
ATOM   6409 C C   . CYS D 2 200 ? 32.20144  47.03042 -1.78796  1.000 27.04330  ? 194 CYS B C   1 
ATOM   6410 O O   . CYS D 2 200 ? 32.57564  48.05071 -2.37717  1.000 22.95655  ? 194 CYS B O   1 
ATOM   6411 C CB  A CYS D 2 200 ? 32.19426  47.86673 0.59168   0.554 22.04642  ? 194 CYS B CB  1 
ATOM   6412 C CB  B CYS D 2 200 ? 32.00975  47.60555 0.66800   0.446 22.30014  ? 194 CYS B CB  1 
ATOM   6413 S SG  A CYS D 2 200 ? 30.46058  48.25529 0.53672   0.554 25.78079  ? 194 CYS B SG  1 
ATOM   6414 S SG  B CYS D 2 200 ? 32.09505  49.40123 0.50357   0.446 27.64226  ? 194 CYS B SG  1 
ATOM   6415 N N   . GLU D 2 201 ? 31.39204  46.12473 -2.33217  1.000 23.62042  ? 195 GLU B N   1 
ATOM   6416 C CA  . GLU D 2 201 ? 30.88282  46.20369 -3.69870  1.000 22.28993  ? 195 GLU B CA  1 
ATOM   6417 C C   . GLU D 2 201 ? 29.39843  46.54287 -3.65463  1.000 23.92154  ? 195 GLU B C   1 
ATOM   6418 O O   . GLU D 2 201 ? 28.61556  45.83630 -3.00711  1.000 25.32906  ? 195 GLU B O   1 
ATOM   6419 C CB  . GLU D 2 201 ? 31.12818  44.87821 -4.41232  1.000 22.76299  ? 195 GLU B CB  1 
ATOM   6420 C CG  . GLU D 2 201 ? 30.56362  44.75279 -5.79998  1.000 26.08807  ? 195 GLU B CG  1 
ATOM   6421 C CD  . GLU D 2 201 ? 30.56470  43.30297 -6.23105  1.000 37.13229  ? 195 GLU B CD  1 
ATOM   6422 O OE1 . GLU D 2 201 ? 29.64263  42.56547 -5.82133  1.000 34.28310  ? 195 GLU B OE1 1 
ATOM   6423 O OE2 . GLU D 2 201 ? 31.51755  42.88806 -6.92529  1.000 40.47794  ? 195 GLU B OE2 1 
ATOM   6424 N N   . VAL D 2 202 ? 29.02153  47.63874 -4.30885  1.000 21.18212  ? 196 VAL B N   1 
ATOM   6425 C CA  . VAL D 2 202 ? 27.64893  48.13731 -4.33880  1.000 21.81656  ? 196 VAL B CA  1 
ATOM   6426 C C   . VAL D 2 202 ? 27.10314  47.95261 -5.74831  1.000 29.91596  ? 196 VAL B C   1 
ATOM   6427 O O   . VAL D 2 202 ? 27.65180  48.51928 -6.70037  1.000 25.80202  ? 196 VAL B O   1 
ATOM   6428 C CB  . VAL D 2 202 ? 27.57908  49.62131 -3.95881  1.000 20.49058  ? 196 VAL B CB  1 
ATOM   6429 C CG1 . VAL D 2 202 ? 26.14803  50.07916 -3.95286  1.000 16.48171  ? 196 VAL B CG1 1 
ATOM   6430 C CG2 . VAL D 2 202 ? 28.28525  49.89301 -2.62233  1.000 25.95434  ? 196 VAL B CG2 1 
ATOM   6431 N N   . THR D 2 203 ? 25.98863  47.23321 -5.88312  1.000 26.29501  ? 197 THR B N   1 
ATOM   6432 C CA  . THR D 2 203 ? 25.39044  46.95950 -7.18887  1.000 25.63303  ? 197 THR B CA  1 
ATOM   6433 C C   . THR D 2 203 ? 23.95911  47.47766 -7.23921  1.000 29.92031  ? 197 THR B C   1 
ATOM   6434 O O   . THR D 2 203 ? 23.16006  47.18936 -6.34017  1.000 26.06973  ? 197 THR B O   1 
ATOM   6435 C CB  . THR D 2 203 ? 25.40832  45.46031 -7.48910  1.000 32.89005  ? 197 THR B CB  1 
ATOM   6436 O OG1 . THR D 2 203 ? 26.76620  44.99246 -7.47997  1.000 29.10636  ? 197 THR B OG1 1 
ATOM   6437 C CG2 . THR D 2 203 ? 24.75936  45.17363 -8.84604  1.000 30.84466  ? 197 THR B CG2 1 
ATOM   6438 N N   . GLN D 2 204 ? 23.64393  48.25138 -8.28009  1.000 24.70931  ? 198 GLN B N   1 
ATOM   6439 C CA  . GLN D 2 204 ? 22.26612  48.61448 -8.60179  1.000 24.25440  ? 198 GLN B CA  1 
ATOM   6440 C C   . GLN D 2 204 ? 22.07941  48.47799 -10.10019 1.000 32.96449  ? 198 GLN B C   1 
ATOM   6441 O O   . GLN D 2 204 ? 22.74629  49.17558 -10.87373 1.000 27.09301  ? 198 GLN B O   1 
ATOM   6442 C CB  . GLN D 2 204 ? 21.91585  50.04427 -8.16556  1.000 25.06462  ? 198 GLN B CB  1 
ATOM   6443 C CG  . GLN D 2 204 ? 21.75623  50.23224 -6.64829  1.000 26.24201  ? 198 GLN B CG  1 
ATOM   6444 C CD  . GLN D 2 204 ? 21.21722  51.61429 -6.30419  1.000 32.13471  ? 198 GLN B CD  1 
ATOM   6445 O OE1 . GLN D 2 204 ? 21.83838  52.63155 -6.62760  1.000 28.28386  ? 198 GLN B OE1 1 
ATOM   6446 N NE2 . GLN D 2 204 ? 20.03867  51.65970 -5.67361  1.000 28.72118  ? 198 GLN B NE2 1 
ATOM   6447 N N   . GLY D 2 205 ? 21.15048  47.61845 -10.49669 1.000 33.91752  ? 199 GLY B N   1 
ATOM   6448 C CA  . GLY D 2 205 ? 20.91341  47.38553 -11.91255 1.000 33.16898  ? 199 GLY B CA  1 
ATOM   6449 C C   . GLY D 2 205 ? 22.18656  46.94204 -12.60874 1.000 29.35715  ? 199 GLY B C   1 
ATOM   6450 O O   . GLY D 2 205 ? 22.81707  45.94338 -12.23702 1.000 33.75957  ? 199 GLY B O   1 
ATOM   6451 N N   . THR D 2 206 ? 22.59200  47.70834 -13.61307 1.000 32.20129  ? 200 THR B N   1 
ATOM   6452 C CA  . THR D 2 206 ? 23.67735  47.31491 -14.49646 1.000 37.50152  ? 200 THR B CA  1 
ATOM   6453 C C   . THR D 2 206 ? 25.05166  47.80681 -14.05001 1.000 35.86656  ? 200 THR B C   1 
ATOM   6454 O O   . THR D 2 206 ? 26.02987  47.56415 -14.76467 1.000 39.83965  ? 200 THR B O   1 
ATOM   6455 C CB  . THR D 2 206 ? 23.38786  47.81446 -15.91908 1.000 41.78033  ? 200 THR B CB  1 
ATOM   6456 O OG1 . THR D 2 206 ? 23.49589  49.24672 -15.97365 1.000 40.20361  ? 200 THR B OG1 1 
ATOM   6457 C CG2 . THR D 2 206 ? 21.98113  47.40420 -16.33899 1.000 47.47191  ? 200 THR B CG2 1 
ATOM   6458 N N   . THR D 2 207 ? 25.16692  48.46935 -12.89485 1.000 30.38523  ? 201 THR B N   1 
ATOM   6459 C CA  . THR D 2 207 ? 26.42464  49.08505 -12.47976 1.000 28.28423  ? 201 THR B CA  1 
ATOM   6460 C C   . THR D 2 207 ? 26.82268  48.59383 -11.09681 1.000 34.12246  ? 201 THR B C   1 
ATOM   6461 O O   . THR D 2 207 ? 25.99038  48.56204 -10.18636 1.000 29.34492  ? 201 THR B O   1 
ATOM   6462 C CB  . THR D 2 207 ? 26.30786  50.61728 -12.46546 1.000 31.18578  ? 201 THR B CB  1 
ATOM   6463 O OG1 . THR D 2 207 ? 25.76405  51.06439 -13.71213 1.000 35.96475  ? 201 THR B OG1 1 
ATOM   6464 C CG2 . THR D 2 207 ? 27.67321  51.27218 -12.24157 1.000 33.91720  ? 201 THR B CG2 1 
ATOM   6465 N N   . SER D 2 208 ? 28.08817  48.20973 -10.94421 1.000 30.68035  ? 202 SER B N   1 
ATOM   6466 C CA  . SER D 2 208 ? 28.68786  47.93017 -9.64442  1.000 30.28643  ? 202 SER B CA  1 
ATOM   6467 C C   . SER D 2 208 ? 29.81984  48.91284 -9.39180  1.000 29.67066  ? 202 SER B C   1 
ATOM   6468 O O   . SER D 2 208 ? 30.57694  49.24337 -10.30970 1.000 29.65282  ? 202 SER B O   1 
ATOM   6469 C CB  . SER D 2 208 ? 29.23413  46.49932 -9.56389  1.000 26.49642  ? 202 SER B CB  1 
ATOM   6470 O OG  . SER D 2 208 ? 28.18584  45.55802 -9.68913  1.000 35.24016  ? 202 SER B OG  1 
ATOM   6471 N N   . VAL D 2 209 ? 29.92627  49.39361 -8.15547  1.000 18.38861  ? 203 VAL B N   1 
ATOM   6472 C CA  . VAL D 2 209 ? 31.05162  50.22123 -7.72948  1.000 21.52993  ? 203 VAL B CA  1 
ATOM   6473 C C   . VAL D 2 209 ? 31.66428  49.56649 -6.50753  1.000 21.06062  ? 203 VAL B C   1 
ATOM   6474 O O   . VAL D 2 209 ? 30.94171  49.17820 -5.57882  1.000 23.55101  ? 203 VAL B O   1 
ATOM   6475 C CB  . VAL D 2 209 ? 30.62946  51.66557 -7.41683  1.000 20.54486  ? 203 VAL B CB  1 
ATOM   6476 C CG1 . VAL D 2 209 ? 31.82669  52.45364 -6.88370  1.000 26.67855  ? 203 VAL B CG1 1 
ATOM   6477 C CG2 . VAL D 2 209 ? 30.06564  52.33794 -8.65774  1.000 30.84458  ? 203 VAL B CG2 1 
ATOM   6478 N N   . THR D 2 210 ? 32.98292  49.41218 -6.52329  1.000 17.29403  ? 204 THR B N   1 
ATOM   6479 C CA  . THR D 2 210 ? 33.72145  48.79594 -5.43274  1.000 22.31271  ? 204 THR B CA  1 
ATOM   6480 C C   . THR D 2 210 ? 34.73200  49.79769 -4.88548  1.000 29.77988  ? 204 THR B C   1 
ATOM   6481 O O   . THR D 2 210 ? 35.53744  50.35562 -5.64024  1.000 20.33634  ? 204 THR B O   1 
ATOM   6482 C CB  . THR D 2 210 ? 34.41978  47.51910 -5.89309  1.000 24.81804  ? 204 THR B CB  1 
ATOM   6483 O OG1 . THR D 2 210 ? 33.43113  46.59215 -6.36684  1.000 24.78512  ? 204 THR B OG1 1 
ATOM   6484 C CG2 . THR D 2 210 ? 35.17352  46.88497 -4.73770  1.000 21.19611  ? 204 THR B CG2 1 
ATOM   6485 N N   . LYS D 2 211 ? 34.66000  50.03907 -3.58176  1.000 20.22861  ? 205 LYS B N   1 
ATOM   6486 C CA  . LYS D 2 211 ? 35.63136  50.81927 -2.83740  1.000 21.02695  ? 205 LYS B CA  1 
ATOM   6487 C C   . LYS D 2 211 ? 36.38547  49.86336 -1.92899  1.000 27.99802  ? 205 LYS B C   1 
ATOM   6488 O O   . LYS D 2 211 ? 35.78721  48.97286 -1.31183  1.000 22.06692  ? 205 LYS B O   1 
ATOM   6489 C CB  . LYS D 2 211 ? 34.94783  51.91240 -2.00944  1.000 25.96532  ? 205 LYS B CB  1 
ATOM   6490 C CG  . LYS D 2 211 ? 34.14404  52.90143 -2.86023  1.000 30.26477  ? 205 LYS B CG  1 
ATOM   6491 C CD  . LYS D 2 211 ? 35.06434  53.83221 -3.66111  1.000 28.23067  ? 205 LYS B CD  1 
ATOM   6492 C CE  . LYS D 2 211 ? 36.02562  54.57440 -2.73200  1.000 39.73672  ? 205 LYS B CE  1 
ATOM   6493 N NZ  . LYS D 2 211 ? 36.80181  55.64481 -3.45006  1.000 48.22995  ? 205 LYS B NZ  1 
ATOM   6494 N N   . SER D 2 212 ? 37.69493  50.03439 -1.85727  1.000 22.43160  ? 206 SER B N   1 
ATOM   6495 C CA  . SER D 2 212 ? 38.51549  49.11818 -1.08868  1.000 21.91525  ? 206 SER B CA  1 
ATOM   6496 C C   . SER D 2 212 ? 39.56535  49.89216 -0.31234  1.000 29.35222  ? 206 SER B C   1 
ATOM   6497 O O   . SER D 2 212 ? 39.75624  51.09697 -0.50430  1.000 22.48375  ? 206 SER B O   1 
ATOM   6498 C CB  . SER D 2 212 ? 39.18756  48.08337 -1.99696  1.000 26.44155  ? 206 SER B CB  1 
ATOM   6499 O OG  . SER D 2 212 ? 39.99700  48.72258 -2.97128  1.000 28.53787  ? 206 SER B OG  1 
ATOM   6500 N N   . PHE D 2 213 ? 40.24538  49.18008 0.58237   1.000 23.20954  ? 207 PHE B N   1 
ATOM   6501 C CA  . PHE D 2 213 ? 41.49286  49.67046 1.14652   1.000 26.96070  ? 207 PHE B CA  1 
ATOM   6502 C C   . PHE D 2 213 ? 42.38803  48.47911 1.43162   1.000 24.53195  ? 207 PHE B C   1 
ATOM   6503 O O   . PHE D 2 213 ? 41.93074  47.33450 1.49617   1.000 28.27780  ? 207 PHE B O   1 
ATOM   6504 C CB  . PHE D 2 213 ? 41.27999  50.50529 2.42047   1.000 27.93334  ? 207 PHE B CB  1 
ATOM   6505 C CG  . PHE D 2 213 ? 40.68644  49.74311 3.56859   1.000 22.63090  ? 207 PHE B CG  1 
ATOM   6506 C CD1 . PHE D 2 213 ? 41.50044  49.05312 4.45899   1.000 28.68593  ? 207 PHE B CD1 1 
ATOM   6507 C CD2 . PHE D 2 213 ? 39.31372  49.73718 3.77645   1.000 25.55453  ? 207 PHE B CD2 1 
ATOM   6508 C CE1 . PHE D 2 213 ? 40.95848  48.35941 5.55402   1.000 28.35873  ? 207 PHE B CE1 1 
ATOM   6509 C CE2 . PHE D 2 213 ? 38.75620  49.04763 4.86083   1.000 26.78345  ? 207 PHE B CE2 1 
ATOM   6510 C CZ  . PHE D 2 213 ? 39.58914  48.35843 5.75500   1.000 22.49344  ? 207 PHE B CZ  1 
ATOM   6511 N N   . ASN D 2 214 ? 43.67417  48.76311 1.59675   1.000 23.69253  ? 208 ASN B N   1 
ATOM   6512 C CA  . ASN D 2 214 ? 44.66061  47.76616 1.98682   1.000 31.31347  ? 208 ASN B CA  1 
ATOM   6513 C C   . ASN D 2 214 ? 45.06844  48.03034 3.42783   1.000 34.51689  ? 208 ASN B C   1 
ATOM   6514 O O   . ASN D 2 214 ? 45.48055  49.14830 3.76051   1.000 36.43192  ? 208 ASN B O   1 
ATOM   6515 C CB  . ASN D 2 214 ? 45.88805  47.80878 1.07125   1.000 35.44222  ? 208 ASN B CB  1 
ATOM   6516 C CG  . ASN D 2 214 ? 45.58622  47.33236 -0.34547  1.000 43.48510  ? 208 ASN B CG  1 
ATOM   6517 O OD1 . ASN D 2 214 ? 46.44308  47.39084 -1.22824  1.000 61.55832  ? 208 ASN B OD1 1 
ATOM   6518 N ND2 . ASN D 2 214 ? 44.36671  46.86759 -0.56876  1.000 44.56200  ? 208 ASN B ND2 1 
ATOM   6519 N N   . ARG D 2 215 ? 44.94765  47.00578 4.27475   1.000 35.31355  ? 209 ARG B N   1 
ATOM   6520 C CA  . ARG D 2 215 ? 45.20266  47.16180 5.70441   1.000 38.64153  ? 209 ARG B CA  1 
ATOM   6521 C C   . ARG D 2 215 ? 46.62571  47.65152 5.94066   1.000 44.78327  ? 209 ARG B C   1 
ATOM   6522 O O   . ARG D 2 215 ? 47.57141  47.18196 5.30079   1.000 42.50486  ? 209 ARG B O   1 
ATOM   6523 C CB  . ARG D 2 215 ? 44.96294  45.83502 6.43960   1.000 32.01397  ? 209 ARG B CB  1 
ATOM   6524 C CG  . ARG D 2 215 ? 45.26043  45.87611 7.93808   1.000 36.95624  ? 209 ARG B CG  1 
ATOM   6525 C CD  . ARG D 2 215 ? 45.07965  44.50700 8.60113   1.000 35.09983  ? 209 ARG B CD  1 
ATOM   6526 N NE  . ARG D 2 215 ? 45.93152  43.47048 8.02453   1.000 35.51130  ? 209 ARG B NE  1 
ATOM   6527 C CZ  . ARG D 2 215 ? 47.22473  43.33705 8.28762   1.000 45.72730  ? 209 ARG B CZ  1 
ATOM   6528 N NH1 . ARG D 2 215 ? 47.84977  44.16428 9.10962   1.000 52.28201  ? 209 ARG B NH1 1 
ATOM   6529 N NH2 . ARG D 2 215 ? 47.90957  42.35282 7.70789   1.000 42.12283  ? 209 ARG B NH2 1 
ATOM   6530 N N   . GLY D 2 216 ? 46.76455  48.62622 6.83963   1.000 51.84373  ? 210 GLY B N   1 
ATOM   6531 C CA  . GLY D 2 216 ? 48.05234  49.21486 7.16485   1.000 56.41729  ? 210 GLY B CA  1 
ATOM   6532 C C   . GLY D 2 216 ? 48.67113  50.05513 6.06353   1.000 60.31141  ? 210 GLY B C   1 
ATOM   6533 O O   . GLY D 2 216 ? 49.75365  49.72155 5.57632   1.000 60.05147  ? 210 GLY B O   1 
ATOM   6534 N N   . GLU D 2 217 ? 48.00376  51.15971 5.66511   1.000 68.00031  ? 211 GLU B N   1 
ATOM   6535 C CA  . GLU D 2 217 ? 48.48591  52.02372 4.57445   1.000 70.22376  ? 211 GLU B CA  1 
ATOM   6536 C C   . GLU D 2 217 ? 48.06375  53.47570 4.84685   1.000 79.00288  ? 211 GLU B C   1 
ATOM   6537 O O   . GLU D 2 217 ? 47.11158  53.99526 4.25709   1.000 79.34663  ? 211 GLU B O   1 
ATOM   6538 C CB  . GLU D 2 217 ? 47.97431  51.55863 3.21067   1.000 59.75153  ? 211 GLU B CB  1 
ATOM   6539 C CG  . GLU D 2 217 ? 48.68079  50.33720 2.64925   1.000 46.59987  ? 211 GLU B CG  1 
ATOM   6540 C CD  . GLU D 2 217 ? 48.55307  50.24052 1.13452   1.000 70.05948  ? 211 GLU B CD  1 
ATOM   6541 O OE1 . GLU D 2 217 ? 48.03174  51.20149 0.51717   1.000 69.35985  ? 211 GLU B OE1 1 
ATOM   6542 O OE2 . GLU D 2 217 ? 48.97603  49.20722 0.56234   1.000 63.01585  ? 211 GLU B OE2 1 
ATOM   6543 N N   . CYS D 2 218 ? 48.80710  54.13962 5.73580   1.000 87.94041  ? 212 CYS B N   1 
ATOM   6544 C CA  . CYS D 2 218 ? 48.61845  55.56830 6.03440   1.000 91.26697  ? 212 CYS B CA  1 
ATOM   6545 C C   . CYS D 2 218 ? 49.72467  56.11150 6.94457   1.000 86.96996  ? 212 CYS B C   1 
ATOM   6546 O O   . CYS D 2 218 ? 49.60594  57.20603 7.50518   1.000 76.76624  ? 212 CYS B O   1 
ATOM   6547 C CB  . CYS D 2 218 ? 47.25367  55.82276 6.68490   1.000 99.65514  ? 212 CYS B CB  1 
ATOM   6548 S SG  . CYS D 2 218 ? 46.07023  56.68911 5.61755   1.000 105.80695 ? 212 CYS B SG  1 
ATOM   6549 N N   . GLY E 3 4   ? -21.64214 55.90620 20.79835  1.000 67.42213  ? 4   GLY C N   1 
ATOM   6550 C CA  . GLY E 3 4   ? -20.29908 56.30383 20.41706  1.000 57.03006  ? 4   GLY C CA  1 
ATOM   6551 C C   . GLY E 3 4   ? -19.30725 55.15502 20.36771  1.000 49.28027  ? 4   GLY C C   1 
ATOM   6552 O O   . GLY E 3 4   ? -18.45786 55.10461 19.48259  1.000 48.20109  ? 4   GLY C O   1 
HETATM 6553 O O3  . UKD E 3 5   ? -14.21983 56.99481 18.81853  1.000 44.52114  ? 5   UKD C O3  1 
HETATM 6554 O O4  . UKD E 3 5   ? -12.98615 54.89944 19.27061  1.000 37.24965  ? 5   UKD C O4  1 
HETATM 6555 P P   . UKD E 3 5   ? -13.65708 56.09578 19.90277  1.000 43.88496  ? 5   UKD C P   1 
HETATM 6556 O O1  . UKD E 3 5   ? -12.68702 56.86054 20.78113  1.000 39.50111  ? 5   UKD C O1  1 
HETATM 6557 C CE2 . UKD E 3 5   ? -15.03903 55.55258 20.89788  1.000 47.31857  ? 5   UKD C CE2 1 
HETATM 6558 N NE1 . UKD E 3 5   ? -15.77563 56.42521 21.62150  1.000 39.87620  ? 5   UKD C NE1 1 
HETATM 6559 N ND1 . UKD E 3 5   ? -16.72583 55.59093 22.23588  1.000 50.20652  ? 5   UKD C ND1 1 
HETATM 6560 C CD2 . UKD E 3 5   ? -15.40394 54.22105 20.96200  1.000 45.89086  ? 5   UKD C CD2 1 
HETATM 6561 N NG  . UKD E 3 5   ? -16.44609 54.27751 21.79909  1.000 47.37209  ? 5   UKD C NG  1 
HETATM 6562 C CB  . UKD E 3 5   ? -17.33901 53.25798 22.32914  1.000 38.02144  ? 5   UKD C CB  1 
HETATM 6563 C CA  . UKD E 3 5   ? -18.51857 53.05896 21.37803  1.000 48.49193  ? 5   UKD C CA  1 
HETATM 6564 N N   . UKD E 3 5   ? -19.41398 54.23388 21.32046  1.000 45.36054  ? 5   UKD C N   1 
HETATM 6565 C C   . UKD E 3 5   ? -19.28390 51.85516 21.84312  1.000 53.75308  ? 5   UKD C C   1 
HETATM 6566 O O   . UKD E 3 5   ? -20.29651 51.97737 22.51559  1.000 43.83427  ? 5   UKD C O   1 
ATOM   6567 N N   . ALA E 3 6   ? -18.76726 50.68326 21.48754  1.000 52.52749  ? 6   ALA C N   1 
ATOM   6568 C CA  . ALA E 3 6   ? -19.31666 49.41267 21.93652  1.000 51.73308  ? 6   ALA C CA  1 
ATOM   6569 C C   . ALA E 3 6   ? -18.99610 49.18160 23.42165  1.000 50.16707  ? 6   ALA C C   1 
ATOM   6570 O O   . ALA E 3 6   ? -18.16274 49.87888 23.99570  1.000 44.07975  ? 6   ALA C O   1 
ATOM   6571 C CB  . ALA E 3 6   ? -18.76812 48.27709 21.07755  1.000 42.72884  ? 6   ALA C CB  1 
ATOM   6572 N N   . GLY E 3 7   ? -19.66640 48.21178 24.04363  1.000 53.15912  ? 7   GLY C N   1 
ATOM   6573 C CA  . GLY E 3 7   ? -19.39401 47.87098 25.42934  1.000 57.46576  ? 7   GLY C CA  1 
ATOM   6574 C C   . GLY E 3 7   ? -19.95434 48.81947 26.46916  1.000 55.41288  ? 7   GLY C C   1 
ATOM   6575 O O   . GLY E 3 7   ? -19.59921 48.69603 27.64916  1.000 49.97601  ? 7   GLY C O   1 
ATOM   6576 N N   . ALA E 3 8   ? -20.81359 49.75807 26.07671  1.000 54.82694  ? 8   ALA C N   1 
ATOM   6577 C CA  . ALA E 3 8   ? -21.40309 50.71509 27.01208  1.000 55.88499  ? 8   ALA C CA  1 
ATOM   6578 C C   . ALA E 3 8   ? -22.65949 50.14260 27.66298  1.000 61.52442  ? 8   ALA C C   1 
ATOM   6579 O O   . ALA E 3 8   ? -22.68743 49.90077 28.86986  1.000 59.52758  ? 8   ALA C O   1 
ATOM   6580 C CB  . ALA E 3 8   ? -21.72278 52.02630 26.30325  1.000 56.85134  ? 8   ALA C CB  1 
ATOM   6581 N N   . ALA F 3 3   ? 39.42488  29.33169 15.97930  1.000 60.79588  ? 3   ALA D N   1 
ATOM   6582 C CA  . ALA F 3 3   ? 38.33422  29.19025 15.01630  1.000 75.63123  ? 3   ALA D CA  1 
ATOM   6583 C C   . ALA F 3 3   ? 36.99187  28.95709 15.71397  1.000 75.10891  ? 3   ALA D C   1 
ATOM   6584 O O   . ALA F 3 3   ? 36.92675  28.25507 16.72596  1.000 77.41272  ? 3   ALA D O   1 
ATOM   6585 C CB  . ALA F 3 3   ? 38.62975  28.05314 14.05113  1.000 72.74551  ? 3   ALA D CB  1 
ATOM   6586 N N   . GLY F 3 4   ? 35.92767  29.54160 15.16344  1.000 68.70432  ? 4   GLY D N   1 
ATOM   6587 C CA  . GLY F 3 4   ? 34.59591  29.43975 15.74404  1.000 67.96910  ? 4   GLY D CA  1 
ATOM   6588 C C   . GLY F 3 4   ? 34.09269  28.01553 15.92384  1.000 69.59133  ? 4   GLY D C   1 
ATOM   6589 O O   . GLY F 3 4   ? 33.46127  27.68248 16.93003  1.000 59.71533  ? 4   GLY D O   1 
HETATM 6590 O O3  . UKD F 3 5   ? 28.30638  25.30310 17.48162  1.000 35.51302  ? 5   UKD D O3  1 
HETATM 6591 O O4  . UKD F 3 5   ? 27.18318  27.00769 15.99335  1.000 23.31928  ? 5   UKD D O4  1 
HETATM 6592 P P   . UKD F 3 5   ? 28.40064  26.64746 16.80280  1.000 37.58633  ? 5   UKD D P   1 
HETATM 6593 O O1  . UKD F 3 5   ? 28.62390  27.68330 17.88931  1.000 40.29849  ? 5   UKD D O1  1 
HETATM 6594 C CE2 . UKD F 3 5   ? 29.77523  26.62050 15.64239  1.000 51.64879  ? 5   UKD D CE2 1 
HETATM 6595 N NE1 . UKD F 3 5   ? 29.86230  27.51781 14.64390  1.000 49.36862  ? 5   UKD D NE1 1 
HETATM 6596 N ND1 . UKD F 3 5   ? 31.04450  27.14632 13.96986  1.000 56.28763  ? 5   UKD D ND1 1 
HETATM 6597 C CD2 . UKD F 3 5   ? 30.78406  25.67341 15.69352  1.000 45.11207  ? 5   UKD D CD2 1 
HETATM 6598 N NG  . UKD F 3 5   ? 31.56367  26.03156 14.65967  1.000 52.33406  ? 5   UKD D NG  1 
HETATM 6599 C CB  . UKD F 3 5   ? 32.80227  25.47284 14.10286  1.000 46.22036  ? 5   UKD D CB  1 
HETATM 6600 C CA  . UKD F 3 5   ? 33.99759  25.74874 15.00840  1.000 57.34495  ? 5   UKD D CA  1 
HETATM 6601 N N   . UKD F 3 5   ? 34.38004  27.16887 14.94198  1.000 62.39432  ? 5   UKD D N   1 
HETATM 6602 C C   . UKD F 3 5   ? 35.18243  24.90482 14.60060  1.000 65.21428  ? 5   UKD D C   1 
HETATM 6603 O O   . UKD F 3 5   ? 36.17594  25.42344 14.12055  1.000 65.58726  ? 5   UKD D O   1 
ATOM   6604 N N   . ALA F 3 6   ? 35.07523  23.59631 14.80234  1.000 57.47555  ? 6   ALA D N   1 
ATOM   6605 C CA  . ALA F 3 6   ? 36.07362  22.66547 14.29687  1.000 64.78233  ? 6   ALA D CA  1 
ATOM   6606 C C   . ALA F 3 6   ? 35.85805  22.41728 12.79764  1.000 57.85783  ? 6   ALA D C   1 
ATOM   6607 O O   . ALA F 3 6   ? 34.88573  22.90457 12.21620  1.000 53.41414  ? 6   ALA D O   1 
ATOM   6608 C CB  . ALA F 3 6   ? 36.02274  21.36353 15.07361  1.000 52.60732  ? 6   ALA D CB  1 
ATOM   6609 N N   . GLY F 3 7   ? 36.78220  21.68349 12.17592  1.000 62.73328  ? 7   GLY D N   1 
ATOM   6610 C CA  . GLY F 3 7   ? 36.68186  21.32171 10.76765  1.000 58.65661  ? 7   GLY D CA  1 
ATOM   6611 C C   . GLY F 3 7   ? 36.58128  22.46611 9.77505   1.000 56.19123  ? 7   GLY D C   1 
ATOM   6612 O O   . GLY F 3 7   ? 37.47193  23.31083 9.68243   1.000 61.70029  ? 7   GLY D O   1 
HETATM 6613 C C1  . EDO G 4 .   ? -8.25817  8.11301  23.91571  1.000 29.10843  ? 301 EDO H C1  1 
HETATM 6614 O O1  . EDO G 4 .   ? -7.17352  8.02484  24.86221  1.000 35.31713  ? 301 EDO H O1  1 
HETATM 6615 C C2  . EDO G 4 .   ? -8.86945  9.51092  23.91451  1.000 28.78158  ? 301 EDO H C2  1 
HETATM 6616 O O2  . EDO G 4 .   ? -9.47246  9.86882  25.18168  1.000 27.21654  ? 301 EDO H O2  1 
HETATM 6617 O O   . HOH H 5 .   ? 3.166     5.076    18.219    1.000 29.08462  ? 401 HOH H O   1 
HETATM 6618 O O   . HOH H 5 .   ? 10.97913  16.84568 19.11902  1.000 31.76556  ? 402 HOH H O   1 
HETATM 6619 O O   . HOH H 5 .   ? -11.27648 28.07486 30.63077  1.000 30.76036  ? 403 HOH H O   1 
HETATM 6620 O O   . HOH H 5 .   ? -1.11257  13.21516 17.44650  1.000 32.55882  ? 404 HOH H O   1 
HETATM 6621 O O   . HOH H 5 .   ? 2.99106   4.18660  4.43616   1.000 23.88958  ? 405 HOH H O   1 
HETATM 6622 O O   . HOH H 5 .   ? -16.84071 16.87586 39.48006  1.000 37.20413  ? 406 HOH H O   1 
HETATM 6623 O O   . HOH H 5 .   ? -21.79188 26.91990 25.41710  1.000 35.25242  ? 407 HOH H O   1 
HETATM 6624 O O   . HOH H 5 .   ? 11.07847  12.75825 3.16930   1.000 43.43225  ? 408 HOH H O   1 
HETATM 6625 O O   . HOH H 5 .   ? -9.63707  2.11903  16.57990  1.000 35.02645  ? 409 HOH H O   1 
HETATM 6626 O O   . HOH H 5 .   ? -4.37492  22.32609 22.60167  1.000 35.47124  ? 410 HOH H O   1 
HETATM 6627 O O   . HOH H 5 .   ? 15.90222  10.37683 19.67960  1.000 28.45634  ? 411 HOH H O   1 
HETATM 6628 O O   . HOH H 5 .   ? 4.732     -3.080   8.045     1.000 37.28303  ? 412 HOH H O   1 
HETATM 6629 O O   . HOH H 5 .   ? 10.003    0.823    0.563     1.000 36.29746  ? 413 HOH H O   1 
HETATM 6630 O O   . HOH H 5 .   ? -18.48385 18.09211 42.58282  1.000 26.77065  ? 414 HOH H O   1 
HETATM 6631 O O   . HOH H 5 .   ? -15.03505 30.72439 28.79189  1.000 33.92645  ? 415 HOH H O   1 
HETATM 6632 O O   . HOH H 5 .   ? -20.78391 24.13261 25.61609  1.000 31.15601  ? 416 HOH H O   1 
HETATM 6633 O O   . HOH H 5 .   ? 11.56191  5.97839  16.47143  1.000 26.76768  ? 417 HOH H O   1 
HETATM 6634 O O   . HOH H 5 .   ? -0.44134  1.39828  2.87016   1.000 32.56358  ? 418 HOH H O   1 
HETATM 6635 O O   . HOH H 5 .   ? 19.19136  32.44829 18.82118  1.000 36.13309  ? 419 HOH H O   1 
HETATM 6636 O O   . HOH H 5 .   ? -6.78781  26.99555 21.82450  1.000 26.66037  ? 420 HOH H O   1 
HETATM 6637 O O   . HOH H 5 .   ? -3.539    -0.163   11.564    1.000 35.94418  ? 421 HOH H O   1 
HETATM 6638 O O   . HOH H 5 .   ? 12.38445  25.73510 16.46025  1.000 41.47389  ? 422 HOH H O   1 
HETATM 6639 O O   . HOH H 5 .   ? 1.65198   10.21721 22.43178  1.000 36.67609  ? 423 HOH H O   1 
HETATM 6640 O O   . HOH H 5 .   ? 7.53649   3.95187  13.55124  1.000 27.31618  ? 424 HOH H O   1 
HETATM 6641 O O   . HOH H 5 .   ? -2.65014  20.89612 26.41813  1.000 30.08033  ? 425 HOH H O   1 
HETATM 6642 O O   . HOH H 5 .   ? 19.75966  13.00904 23.95502  1.000 29.88412  ? 426 HOH H O   1 
HETATM 6643 O O   . HOH H 5 .   ? -5.47828  20.52162 6.98646   1.000 34.94090  ? 427 HOH H O   1 
HETATM 6644 O O   . HOH H 5 .   ? -4.01208  24.38518 30.73155  1.000 36.48781  ? 428 HOH H O   1 
HETATM 6645 O O   . HOH H 5 .   ? -5.33786  10.59772 24.60744  1.000 26.57661  ? 429 HOH H O   1 
HETATM 6646 O O   . HOH H 5 .   ? 0.40680   4.80145  22.97083  1.000 28.78971  ? 430 HOH H O   1 
HETATM 6647 O O   . HOH H 5 .   ? 10.90437  -1.21680 10.55838  1.000 36.40895  ? 431 HOH H O   1 
HETATM 6648 O O   . HOH H 5 .   ? -13.40065 28.41220 16.11421  1.000 25.58745  ? 432 HOH H O   1 
HETATM 6649 O O   . HOH H 5 .   ? -1.63138  18.03528 11.89157  1.000 25.66032  ? 433 HOH H O   1 
HETATM 6650 O O   . HOH H 5 .   ? -19.67915 33.10139 32.60648  1.000 42.88065  ? 434 HOH H O   1 
HETATM 6651 O O   . HOH H 5 .   ? -2.69593  20.68333 19.87300  1.000 22.49056  ? 435 HOH H O   1 
HETATM 6652 O O   . HOH H 5 .   ? 28.64849  14.13650 15.23860  1.000 45.08239  ? 436 HOH H O   1 
HETATM 6653 O O   . HOH H 5 .   ? -9.80119  5.74952  22.16295  1.000 30.80957  ? 437 HOH H O   1 
HETATM 6654 O O   . HOH H 5 .   ? -20.12310 19.25304 36.03887  1.000 41.97043  ? 438 HOH H O   1 
HETATM 6655 O O   . HOH H 5 .   ? -13.516   22.567   9.096     1.000 24.06668  ? 439 HOH H O   1 
HETATM 6656 O O   . HOH H 5 .   ? -20.89561 25.95029 22.54293  1.000 27.06453  ? 440 HOH H O   1 
HETATM 6657 O O   . HOH H 5 .   ? -19.70816 33.25600 22.37878  1.000 43.90666  ? 441 HOH H O   1 
HETATM 6658 O O   . HOH H 5 .   ? 0.36166   1.68559  14.26006  1.000 29.41283  ? 442 HOH H O   1 
HETATM 6659 O O   . HOH H 5 .   ? -2.09991  20.22864 29.27631  1.000 35.02610  ? 443 HOH H O   1 
HETATM 6660 O O   . HOH H 5 .   ? 27.06450  24.06863 -2.42550  1.000 37.87496  ? 444 HOH H O   1 
HETATM 6661 O O   . HOH H 5 .   ? 2.88643   8.86777  13.62522  1.000 23.23121  ? 445 HOH H O   1 
HETATM 6662 O O   . HOH H 5 .   ? -5.82307  23.06706 15.35611  1.000 29.20036  ? 446 HOH H O   1 
HETATM 6663 O O   . HOH H 5 .   ? -7.10548  -0.10629 22.05591  1.000 35.03314  ? 447 HOH H O   1 
HETATM 6664 O O   . HOH H 5 .   ? -1.47280  15.73634 21.89332  1.000 30.82910  ? 448 HOH H O   1 
HETATM 6665 O O   . HOH H 5 .   ? 0.00011   13.46641 20.73373  1.000 34.70215  ? 449 HOH H O   1 
HETATM 6666 O O   . HOH H 5 .   ? -12.94395 32.04678 23.75815  1.000 30.78424  ? 450 HOH H O   1 
HETATM 6667 O O   . HOH H 5 .   ? 9.19931   3.89092  16.08100  1.000 36.38476  ? 451 HOH H O   1 
HETATM 6668 O O   . HOH H 5 .   ? 4.73767   -0.48324 9.40767   1.000 32.76270  ? 452 HOH H O   1 
HETATM 6669 O O   . HOH H 5 .   ? -19.39664 19.36912 33.27096  1.000 39.81831  ? 453 HOH H O   1 
HETATM 6670 O O   . HOH H 5 .   ? 8.50505   20.49438 18.03190  1.000 38.78623  ? 454 HOH H O   1 
HETATM 6671 O O   . HOH H 5 .   ? -0.97799  14.88840 19.04505  1.000 34.42399  ? 455 HOH H O   1 
HETATM 6672 O O   . HOH H 5 .   ? 20.47458  33.94313 17.64271  1.000 35.37886  ? 456 HOH H O   1 
HETATM 6673 O O   . HOH H 5 .   ? -20.06912 17.06713 32.22166  1.000 44.26964  ? 457 HOH H O   1 
HETATM 6674 O O   . HOH H 5 .   ? -26.14907 25.35658 22.16877  1.000 50.73438  ? 458 HOH H O   1 
HETATM 6675 O O   . HOH H 5 .   ? -23.89112 29.00439 22.56058  1.000 42.20820  ? 459 HOH H O   1 
HETATM 6676 O O   . HOH H 5 .   ? 4.71734   9.41809  16.03310  1.000 37.20482  ? 460 HOH H O   1 
HETATM 6677 O O   . HOH H 5 .   ? -4.80565  25.27096 23.20726  1.000 35.43976  ? 461 HOH H O   1 
HETATM 6678 O O   . HOH I 5 .   ? 13.08988  16.03472 25.76003  1.000 29.41802  ? 301 HOH L O   1 
HETATM 6679 O O   . HOH I 5 .   ? -8.17374  4.17849  23.90133  1.000 26.47990  ? 302 HOH L O   1 
HETATM 6680 O O   . HOH I 5 .   ? 26.05995  32.27457 32.86159  1.000 42.57647  ? 303 HOH L O   1 
HETATM 6681 O O   . HOH I 5 .   ? -7.79042  19.94837 41.37934  1.000 31.13024  ? 304 HOH L O   1 
HETATM 6682 O O   . HOH I 5 .   ? 12.19442  29.35551 29.03790  1.000 36.20141  ? 305 HOH L O   1 
HETATM 6683 O O   . HOH I 5 .   ? -16.12058 3.06317  44.04844  1.000 33.54448  ? 306 HOH L O   1 
HETATM 6684 O O   . HOH I 5 .   ? 6.76151   15.56047 35.99212  1.000 42.44902  ? 307 HOH L O   1 
HETATM 6685 O O   . HOH I 5 .   ? -17.96152 -4.88576 30.02499  1.000 41.71332  ? 308 HOH L O   1 
HETATM 6686 O O   . HOH I 5 .   ? -12.33068 4.92840  22.28026  1.000 23.60716  ? 309 HOH L O   1 
HETATM 6687 O O   . HOH I 5 .   ? -6.93617  1.84640  32.04807  1.000 32.05340  ? 310 HOH L O   1 
HETATM 6688 O O   . HOH I 5 .   ? -4.71544  3.64245  36.84170  1.000 27.63679  ? 311 HOH L O   1 
HETATM 6689 O O   . HOH I 5 .   ? 6.92400   24.19386 45.02727  1.000 32.19695  ? 312 HOH L O   1 
HETATM 6690 O O   . HOH I 5 .   ? -7.26630  -3.19683 32.38312  1.000 40.70883  ? 313 HOH L O   1 
HETATM 6691 O O   . HOH I 5 .   ? -3.82300  14.05251 45.35521  1.000 28.02064  ? 314 HOH L O   1 
HETATM 6692 O O   . HOH I 5 .   ? -10.13913 2.50912  25.38501  1.000 24.05868  ? 315 HOH L O   1 
HETATM 6693 O O   . HOH I 5 .   ? -7.69346  3.61303  33.91848  1.000 25.87810  ? 316 HOH L O   1 
HETATM 6694 O O   . HOH I 5 .   ? -17.29774 10.02901 25.74515  1.000 23.10999  ? 317 HOH L O   1 
HETATM 6695 O O   . HOH I 5 .   ? 10.20872  17.04424 30.08978  1.000 38.73881  ? 318 HOH L O   1 
HETATM 6696 O O   . HOH I 5 .   ? -7.39658  11.43210 26.05776  1.000 20.94433  ? 319 HOH L O   1 
HETATM 6697 O O   . HOH I 5 .   ? -15.35659 6.08200  45.88400  1.000 23.71969  ? 320 HOH L O   1 
HETATM 6698 O O   . HOH I 5 .   ? 11.97616  28.43555 31.86681  1.000 28.25439  ? 321 HOH L O   1 
HETATM 6699 O O   . HOH I 5 .   ? 2.66877   12.34891 29.23375  1.000 46.61919  ? 322 HOH L O   1 
HETATM 6700 O O   . HOH I 5 .   ? -10.45767 -1.37704 31.96098  1.000 31.66549  ? 323 HOH L O   1 
HETATM 6701 O O   . HOH I 5 .   ? 7.32724   24.36992 31.54863  1.000 23.82186  ? 324 HOH L O   1 
HETATM 6702 O O   . HOH I 5 .   ? 3.40098   13.37364 33.10256  1.000 33.75077  ? 325 HOH L O   1 
HETATM 6703 O O   . HOH I 5 .   ? 3.88901   25.33853 41.43999  1.000 34.79004  ? 326 HOH L O   1 
HETATM 6704 O O   . HOH I 5 .   ? 22.06713  37.79635 28.72184  1.000 32.07172  ? 327 HOH L O   1 
HETATM 6705 O O   . HOH I 5 .   ? 21.79018  30.60389 38.26756  1.000 34.57374  ? 328 HOH L O   1 
HETATM 6706 O O   . HOH I 5 .   ? -11.28672 14.28730 44.14862  1.000 27.94140  ? 329 HOH L O   1 
HETATM 6707 O O   . HOH I 5 .   ? -10.82995 -0.74651 35.09239  1.000 24.81715  ? 330 HOH L O   1 
HETATM 6708 O O   . HOH I 5 .   ? -13.54335 2.41146  46.86193  1.000 42.76391  ? 331 HOH L O   1 
HETATM 6709 O O   . HOH I 5 .   ? 11.07979  24.05712 24.61717  1.000 25.60938  ? 332 HOH L O   1 
HETATM 6710 O O   . HOH I 5 .   ? -0.88126  19.44264 32.95892  1.000 26.55135  ? 333 HOH L O   1 
HETATM 6711 O O   . HOH I 5 .   ? 1.57957   23.81240 30.67727  1.000 28.41489  ? 334 HOH L O   1 
HETATM 6712 O O   . HOH I 5 .   ? -21.85400 12.65683 33.34499  1.000 30.24594  ? 335 HOH L O   1 
HETATM 6713 O O   . HOH I 5 .   ? 4.02346   13.25614 41.17979  1.000 37.65693  ? 336 HOH L O   1 
HETATM 6714 O O   . HOH I 5 .   ? -7.62496  8.04186  27.72143  1.000 22.78130  ? 337 HOH L O   1 
HETATM 6715 O O   . HOH I 5 .   ? 5.40708   23.33230 36.68842  1.000 23.01871  ? 338 HOH L O   1 
HETATM 6716 O O   . HOH I 5 .   ? -21.06063 0.45591  37.93691  1.000 34.04656  ? 339 HOH L O   1 
HETATM 6717 O O   . HOH I 5 .   ? -2.91207  19.73147 34.80132  1.000 21.77491  ? 340 HOH L O   1 
HETATM 6718 O O   . HOH I 5 .   ? -9.51076  3.04452  41.85202  1.000 33.47549  ? 341 HOH L O   1 
HETATM 6719 O O   . HOH I 5 .   ? -26.59720 9.09604  29.04956  1.000 37.06370  ? 342 HOH L O   1 
HETATM 6720 O O   . HOH I 5 .   ? -1.90162  6.61278  45.93089  1.000 43.93978  ? 343 HOH L O   1 
HETATM 6721 O O   . HOH I 5 .   ? 1.16500   18.58855 50.26985  1.000 31.86068  ? 344 HOH L O   1 
HETATM 6722 O O   . HOH I 5 .   ? -14.65614 16.09674 41.46010  1.000 30.23495  ? 345 HOH L O   1 
HETATM 6723 O O   . HOH I 5 .   ? -20.57048 7.78705  41.92966  1.000 25.83174  ? 346 HOH L O   1 
HETATM 6724 O O   . HOH I 5 .   ? -2.68871  26.41349 34.05278  1.000 38.81837  ? 347 HOH L O   1 
HETATM 6725 O O   . HOH I 5 .   ? -3.01706  2.98561  29.28440  1.000 33.70657  ? 348 HOH L O   1 
HETATM 6726 O O   . HOH I 5 .   ? 25.58264  23.17859 14.50051  1.000 35.62449  ? 349 HOH L O   1 
HETATM 6727 O O   . HOH I 5 .   ? 21.61696  33.00249 38.23504  1.000 40.51520  ? 350 HOH L O   1 
HETATM 6728 O O   . HOH I 5 .   ? 19.42769  31.33944 21.43204  1.000 31.22007  ? 351 HOH L O   1 
HETATM 6729 O O   . HOH I 5 .   ? 15.44633  12.67350 27.22443  1.000 34.26447  ? 352 HOH L O   1 
HETATM 6730 O O   . HOH I 5 .   ? 2.66671   24.18606 46.10866  1.000 35.88150  ? 353 HOH L O   1 
HETATM 6731 O O   . HOH I 5 .   ? -13.75319 -6.49060 31.73653  1.000 37.54830  ? 354 HOH L O   1 
HETATM 6732 O O   . HOH I 5 .   ? 16.78480  28.75279 20.65883  1.000 33.55566  ? 355 HOH L O   1 
HETATM 6733 O O   . HOH I 5 .   ? -19.23624 14.49621 35.49593  1.000 25.51022  ? 356 HOH L O   1 
HETATM 6734 O O   . HOH I 5 .   ? -26.98333 10.14392 35.47458  1.000 32.71533  ? 357 HOH L O   1 
HETATM 6735 O O   . HOH I 5 .   ? 17.98462  24.90023 47.18301  1.000 40.42698  ? 358 HOH L O   1 
HETATM 6736 O O   . HOH I 5 .   ? 9.63641   28.58383 26.91730  1.000 38.35693  ? 359 HOH L O   1 
HETATM 6737 O O   . HOH I 5 .   ? -21.76475 12.71457 36.23856  1.000 43.50743  ? 360 HOH L O   1 
HETATM 6738 O O   . HOH I 5 .   ? 0.37172   9.01017  28.83821  1.000 34.06365  ? 361 HOH L O   1 
HETATM 6739 O O   . HOH I 5 .   ? -0.86864  21.30866 31.09799  1.000 42.18270  ? 362 HOH L O   1 
HETATM 6740 O O   . HOH I 5 .   ? -15.66260 5.29058  17.14835  1.000 28.38051  ? 363 HOH L O   1 
HETATM 6741 O O   . HOH I 5 .   ? -9.76090  4.39233  49.96499  1.000 37.81408  ? 364 HOH L O   1 
HETATM 6742 O O   . HOH I 5 .   ? 5.64440   15.47659 33.54738  1.000 38.42124  ? 365 HOH L O   1 
HETATM 6743 O O   . HOH I 5 .   ? -2.79440  5.06152  44.24086  1.000 40.76027  ? 366 HOH L O   1 
HETATM 6744 O O   . HOH I 5 .   ? -9.17006  -0.01135 25.22047  1.000 29.24910  ? 367 HOH L O   1 
HETATM 6745 O O   . HOH I 5 .   ? -18.04629 1.27183  42.38552  1.000 36.25419  ? 368 HOH L O   1 
HETATM 6746 O O   . HOH J 5 .   ? 25.79845  63.68618 3.68298   1.000 27.68713  ? 301 HOH A O   1 
HETATM 6747 O O   . HOH J 5 .   ? 10.12779  43.48947 19.59628  1.000 30.83136  ? 302 HOH A O   1 
HETATM 6748 O O   . HOH J 5 .   ? 14.69036  46.55408 19.77965  1.000 27.27553  ? 303 HOH A O   1 
HETATM 6749 O O   . HOH J 5 .   ? 18.91751  58.22907 25.16320  1.000 25.06312  ? 304 HOH A O   1 
HETATM 6750 O O   . HOH J 5 .   ? -0.62735  46.90463 12.30589  1.000 29.77350  ? 305 HOH A O   1 
HETATM 6751 O O   . HOH J 5 .   ? 28.36961  43.13659 20.39356  1.000 38.26829  ? 306 HOH A O   1 
HETATM 6752 O O   . HOH J 5 .   ? 4.27947   45.82491 16.35365  1.000 33.36445  ? 307 HOH A O   1 
HETATM 6753 O O   . HOH J 5 .   ? 11.34326  53.59801 28.30769  1.000 35.74782  ? 308 HOH A O   1 
HETATM 6754 O O   . HOH J 5 .   ? -18.78111 49.36283 30.35693  1.000 44.66610  ? 309 HOH A O   1 
HETATM 6755 O O   . HOH J 5 .   ? 6.36253   53.60495 17.85310  1.000 33.16488  ? 310 HOH A O   1 
HETATM 6756 O O   . HOH J 5 .   ? 38.82597  68.18298 11.03295  1.000 32.79352  ? 311 HOH A O   1 
HETATM 6757 O O   . HOH J 5 .   ? 40.14914  59.88026 14.09850  1.000 37.36783  ? 312 HOH A O   1 
HETATM 6758 O O   . HOH J 5 .   ? 14.92452  52.44463 27.33275  1.000 28.63839  ? 313 HOH A O   1 
HETATM 6759 O O   . HOH J 5 .   ? 25.64163  44.54463 28.76913  1.000 28.50573  ? 314 HOH A O   1 
HETATM 6760 O O   . HOH J 5 .   ? 37.75131  67.11289 14.04499  1.000 35.39788  ? 315 HOH A O   1 
HETATM 6761 O O   . HOH J 5 .   ? 21.50097  62.98174 14.49326  1.000 32.83994  ? 316 HOH A O   1 
HETATM 6762 O O   . HOH J 5 .   ? 28.01238  69.14720 6.09206   1.000 36.58325  ? 317 HOH A O   1 
HETATM 6763 O O   . HOH J 5 .   ? 22.97243  50.96018 12.53358  1.000 31.72834  ? 318 HOH A O   1 
HETATM 6764 O O   . HOH J 5 .   ? -9.73442  53.87035 22.13435  1.000 34.94342  ? 319 HOH A O   1 
HETATM 6765 O O   . HOH J 5 .   ? 36.93825  74.13130 14.37560  1.000 41.35207  ? 320 HOH A O   1 
HETATM 6766 O O   . HOH J 5 .   ? -16.08454 53.57540 26.17764  1.000 35.97047  ? 321 HOH A O   1 
HETATM 6767 O O   . HOH J 5 .   ? 13.58630  50.08458 27.25550  1.000 30.29505  ? 322 HOH A O   1 
HETATM 6768 O O   . HOH J 5 .   ? 19.93254  61.40595 10.31495  1.000 39.33254  ? 323 HOH A O   1 
HETATM 6769 O O   . HOH J 5 .   ? 31.404    68.920   -0.126    1.000 40.59708  ? 324 HOH A O   1 
HETATM 6770 O O   . HOH J 5 .   ? 27.20986  40.38020 18.16032  1.000 43.35707  ? 325 HOH A O   1 
HETATM 6771 O O   . HOH J 5 .   ? 23.61493  68.01189 15.14729  1.000 24.22336  ? 326 HOH A O   1 
HETATM 6772 O O   . HOH J 5 .   ? 15.81180  48.53230 23.44635  1.000 24.18758  ? 327 HOH A O   1 
HETATM 6773 O O   . HOH J 5 .   ? 18.78816  42.38249 23.93897  1.000 24.57349  ? 328 HOH A O   1 
HETATM 6774 O O   . HOH J 5 .   ? 30.52265  69.54761 20.57343  1.000 27.28309  ? 329 HOH A O   1 
HETATM 6775 O O   . HOH J 5 .   ? 27.18686  50.90744 11.94845  1.000 28.05375  ? 330 HOH A O   1 
HETATM 6776 O O   . HOH J 5 .   ? 28.14111  46.92216 14.85686  1.000 31.56206  ? 331 HOH A O   1 
HETATM 6777 O O   . HOH J 5 .   ? 19.03112  60.84388 7.48882   1.000 35.84494  ? 332 HOH A O   1 
HETATM 6778 O O   . HOH J 5 .   ? 20.95793  64.97110 6.04121   1.000 35.42140  ? 333 HOH A O   1 
HETATM 6779 O O   . HOH J 5 .   ? 18.15511  45.02829 14.13198  1.000 29.81559  ? 334 HOH A O   1 
HETATM 6780 O O   . HOH J 5 .   ? 39.51015  60.67709 16.14098  1.000 33.37164  ? 335 HOH A O   1 
HETATM 6781 O O   . HOH J 5 .   ? 14.58135  42.22302 23.21384  1.000 35.08526  ? 336 HOH A O   1 
HETATM 6782 O O   . HOH J 5 .   ? 19.78812  61.16537 17.20792  1.000 27.95799  ? 337 HOH A O   1 
HETATM 6783 O O   . HOH J 5 .   ? 17.92328  50.57652 31.28104  1.000 35.30507  ? 338 HOH A O   1 
HETATM 6784 O O   . HOH J 5 .   ? 16.46948  43.93745 23.09415  1.000 31.83838  ? 339 HOH A O   1 
HETATM 6785 O O   . HOH J 5 .   ? 24.90432  42.06485 28.67012  1.000 33.56799  ? 340 HOH A O   1 
HETATM 6786 O O   . HOH J 5 .   ? 8.50416   57.55228 22.66192  1.000 44.49823  ? 341 HOH A O   1 
HETATM 6787 O O   . HOH J 5 .   ? 28.07578  36.70698 15.37288  1.000 44.91910  ? 342 HOH A O   1 
HETATM 6788 O O   . HOH J 5 .   ? 22.82051  63.99493 21.59529  1.000 28.66707  ? 343 HOH A O   1 
HETATM 6789 O O   . HOH J 5 .   ? 13.86169  48.69901 21.08883  1.000 35.39743  ? 344 HOH A O   1 
HETATM 6790 O O   . HOH J 5 .   ? 40.82568  56.88429 13.07325  1.000 37.68823  ? 345 HOH A O   1 
HETATM 6791 O O   . HOH J 5 .   ? 15.61304  48.16649 17.36025  1.000 41.69452  ? 346 HOH A O   1 
HETATM 6792 O O   . HOH K 5 .   ? 25.76421  37.91018 4.88703   1.000 46.83530  ? 301 HOH B O   1 
HETATM 6793 O O   . HOH K 5 .   ? 20.88294  54.25530 -8.18526  1.000 32.64228  ? 302 HOH B O   1 
HETATM 6794 O O   . HOH K 5 .   ? 25.59929  49.04548 9.40160   1.000 31.59713  ? 303 HOH B O   1 
HETATM 6795 O O   . HOH K 5 .   ? 36.10415  37.19148 12.34514  1.000 39.09133  ? 304 HOH B O   1 
HETATM 6796 O O   . HOH K 5 .   ? 30.46650  45.87928 14.54161  1.000 36.16795  ? 305 HOH B O   1 
HETATM 6797 O O   . HOH K 5 .   ? 17.62670  62.20144 5.66206   1.000 39.57568  ? 306 HOH B O   1 
HETATM 6798 O O   . HOH K 5 .   ? 43.71251  49.13626 9.95407   1.000 33.17905  ? 307 HOH B O   1 
HETATM 6799 O O   . HOH K 5 .   ? 25.14848  52.16745 10.87540  1.000 25.53214  ? 308 HOH B O   1 
HETATM 6800 O O   . HOH K 5 .   ? 41.64180  55.02138 16.76771  1.000 35.61011  ? 309 HOH B O   1 
HETATM 6801 O O   . HOH K 5 .   ? 21.70253  43.38150 7.82012   1.000 35.78818  ? 310 HOH B O   1 
HETATM 6802 O O   . HOH K 5 .   ? 13.11638  52.84637 -3.71287  1.000 39.54351  ? 311 HOH B O   1 
HETATM 6803 O O   . HOH K 5 .   ? 40.27241  53.59203 0.18628   1.000 32.03147  ? 312 HOH B O   1 
HETATM 6804 O O   . HOH K 5 .   ? -12.85664 55.24073 5.37648   1.000 33.89764  ? 313 HOH B O   1 
HETATM 6805 O O   . HOH K 5 .   ? 34.14140  44.08763 -6.98678  1.000 31.85174  ? 314 HOH B O   1 
HETATM 6806 O O   . HOH K 5 .   ? 36.42287  51.30274 14.81867  1.000 26.62857  ? 315 HOH B O   1 
HETATM 6807 O O   . HOH K 5 .   ? 28.27069  55.08384 -7.38200  1.000 34.20923  ? 316 HOH B O   1 
HETATM 6808 O O   . HOH K 5 .   ? 35.30893  51.43124 10.95430  1.000 25.24067  ? 317 HOH B O   1 
HETATM 6809 O O   . HOH K 5 .   ? 26.67212  45.12070 12.97067  1.000 34.69190  ? 318 HOH B O   1 
HETATM 6810 O O   . HOH K 5 .   ? 9.43995   62.53590 10.46540  1.000 45.21615  ? 319 HOH B O   1 
HETATM 6811 O O   . HOH K 5 .   ? 24.35943  60.68805 -4.72009  1.000 36.67394  ? 320 HOH B O   1 
HETATM 6812 O O   . HOH K 5 .   ? 28.25166  43.43289 11.55369  1.000 26.47914  ? 321 HOH B O   1 
HETATM 6813 O O   . HOH K 5 .   ? 3.25213   60.86516 12.52275  1.000 36.48850  ? 322 HOH B O   1 
HETATM 6814 O O   . HOH K 5 .   ? -7.96088  45.48369 0.90890   1.000 45.58178  ? 323 HOH B O   1 
HETATM 6815 O O   . HOH K 5 .   ? 44.66925  51.35368 1.29123   1.000 30.05457  ? 324 HOH B O   1 
HETATM 6816 O O   . HOH K 5 .   ? 26.35340  41.52358 14.92841  1.000 47.60992  ? 325 HOH B O   1 
HETATM 6817 O O   . HOH K 5 .   ? 39.18243  41.85751 -1.07900  1.000 31.13086  ? 326 HOH B O   1 
HETATM 6818 O O   . HOH K 5 .   ? 27.13985  43.96264 -4.87088  1.000 32.13299  ? 327 HOH B O   1 
HETATM 6819 O O   . HOH K 5 .   ? 36.16884  55.81158 0.98604   1.000 23.76936  ? 328 HOH B O   1 
HETATM 6820 O O   . HOH K 5 .   ? 2.46984   49.22638 -5.08467  1.000 39.39588  ? 329 HOH B O   1 
HETATM 6821 O O   . HOH K 5 .   ? 15.99762  58.25296 -13.62240 1.000 39.61265  ? 330 HOH B O   1 
HETATM 6822 O O   . HOH K 5 .   ? 31.66315  56.91157 -4.86259  1.000 29.15229  ? 331 HOH B O   1 
HETATM 6823 O O   . HOH K 5 .   ? 3.76865   51.01654 -5.94184  1.000 41.50582  ? 332 HOH B O   1 
HETATM 6824 O O   . HOH K 5 .   ? 19.75124  60.11010 1.86431   1.000 34.14501  ? 333 HOH B O   1 
HETATM 6825 O O   . HOH K 5 .   ? 38.37848  48.85419 -5.48417  1.000 32.67132  ? 334 HOH B O   1 
HETATM 6826 O O   . HOH K 5 .   ? 28.68326  40.41045 2.12723   1.000 29.09699  ? 335 HOH B O   1 
HETATM 6827 O O   . HOH K 5 .   ? 17.56982  49.74682 8.83630   1.000 40.10725  ? 336 HOH B O   1 
HETATM 6828 O O   . HOH K 5 .   ? 34.33543  46.54399 19.47990  1.000 37.19282  ? 337 HOH B O   1 
HETATM 6829 O O   . HOH K 5 .   ? -18.98658 49.55501 0.55707   1.000 45.74476  ? 338 HOH B O   1 
HETATM 6830 O O   . HOH K 5 .   ? -3.24324  58.98829 -10.43644 1.000 43.58017  ? 339 HOH B O   1 
HETATM 6831 O O   . HOH K 5 .   ? 36.40253  57.34752 3.77876   1.000 38.43948  ? 340 HOH B O   1 
HETATM 6832 O O   . HOH K 5 .   ? 32.93134  34.46594 5.61548   1.000 45.74875  ? 341 HOH B O   1 
HETATM 6833 O O   . HOH K 5 .   ? 27.31609  41.14297 11.93795  1.000 35.36893  ? 342 HOH B O   1 
HETATM 6834 O O   . HOH K 5 .   ? 24.75094  48.90632 12.00395  1.000 30.61216  ? 343 HOH B O   1 
HETATM 6835 O O   . HOH L 5 .   ? 39.25056  23.88032 8.32153   1.000 51.36336  ? 101 HOH D O   1 
# 
