data_8UIH
# 
_entry.id   8UIH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UIH         pdb_00008uih 10.2210/pdb8uih/pdb 
WWPDB D_1000277373 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UIH 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              hunter@salk.edu 
_pdbx_contact_author.name_first         Tony 
_pdbx_contact_author.name_last          Hunter 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7691-6993 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kalagiri, R.'    1 0000-0002-4817-3563 
'Stanfield, R.L.' 2 0000-0001-9521-9184 
'Hunter, T.'      3 0000-0002-7691-6993 
'Wilson, I.A.'    4 0000-0002-6469-2419 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.11.04.621849 
_citation.pdbx_database_id_PubMed   39574610 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Martyn, G.D.'     1  ?                   
primary 'Kalagiri, R.'     2  ?                   
primary 'Veggiani, G.'     3  ?                   
primary 'Stanfield, R.L.'  4  ?                   
primary 'Choudhuri, I.'    5  ?                   
primary 'Sala, M.'         6  ?                   
primary 'Meisenhelder, J.' 7  ?                   
primary 'Chen, C.'         8  ?                   
primary 'Biswas, A.'       9  ?                   
primary 'Levy, R.M.'       10 ?                   
primary 'Lyumkis, D.'      11 ?                   
primary 'Wilson, I.A.'     12 ?                   
primary 'Hunter, T.'       13 0000-0002-7691-6993 
primary 'Sidhu, S.S.'      14 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'hSC44.ck.20 Fab heavy chain' 23597.467 1   ? ? ? 'Fab heavy chain' 
2 polymer     man 'hSC44.ck.20 Fab light chain' 23879.383 1   ? ? ? 'Fab light chain' 
3 polymer     syn '3ptza peptide'               748.641   1   ? ? ? ?                 
4 non-polymer syn 1,2-ETHANEDIOL                62.068    2   ? ? ? ?                 
5 water       nat water                         18.015    263 ? ? ? ?                 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGTGSRFAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGTGSRFAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
H ? 
2 'polypeptide(L)' no no  
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
L ? 
3 'polypeptide(L)' no yes 'AGAG(UKD)AGAG' AGAGXAGAG D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
4 1,2-ETHANEDIOL EDO 
5 water          HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  THR n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  SER n 
1 29  ILE n 
1 30  ASP n 
1 31  SER n 
1 32  TYR n 
1 33  GLY n 
1 34  PHE n 
1 35  SER n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  HIS n 
1 48  ILE n 
1 49  GLY n 
1 50  TYR n 
1 51  LEU n 
1 52  THR n 
1 53  ALA n 
1 54  GLY n 
1 55  GLY n 
1 56  ARG n 
1 57  ALA n 
1 58  PHE n 
1 59  TYR n 
1 60  ALA n 
1 61  SER n 
1 62  TRP n 
1 63  ALA n 
1 64  LYS n 
1 65  SER n 
1 66  ARG n 
1 67  SER n 
1 68  THR n 
1 69  ILE n 
1 70  THR n 
1 71  ARG n 
1 72  ASN n 
1 73  THR n 
1 74  ASN n 
1 75  GLU n 
1 76  ASN n 
1 77  THR n 
1 78  VAL n 
1 79  THR n 
1 80  LEU n 
1 81  LYS n 
1 82  MET n 
1 83  ASN n 
1 84  SER n 
1 85  LEU n 
1 86  ARG n 
1 87  ALA n 
1 88  GLU n 
1 89  ASP n 
1 90  THR n 
1 91  ALA n 
1 92  VAL n 
1 93  TYR n 
1 94  TYR n 
1 95  CYS n 
1 96  ALA n 
1 97  LYS n 
1 98  LEU n 
1 99  GLY n 
1 100 THR n 
1 101 GLY n 
1 102 SER n 
1 103 ARG n 
1 104 PHE n 
1 105 ALA n 
1 106 ILE n 
1 107 TRP n 
1 108 GLY n 
1 109 GLN n 
1 110 GLY n 
1 111 THR n 
1 112 LEU n 
1 113 VAL n 
1 114 THR n 
1 115 VAL n 
1 116 SER n 
1 117 SER n 
1 118 ALA n 
1 119 SER n 
1 120 THR n 
1 121 LYS n 
1 122 GLY n 
1 123 PRO n 
1 124 SER n 
1 125 VAL n 
1 126 PHE n 
1 127 PRO n 
1 128 LEU n 
1 129 ALA n 
1 130 PRO n 
1 131 SER n 
1 132 SER n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 SER n 
1 137 GLY n 
1 138 GLY n 
1 139 THR n 
1 140 ALA n 
1 141 ALA n 
1 142 LEU n 
1 143 GLY n 
1 144 CYS n 
1 145 LEU n 
1 146 VAL n 
1 147 LYS n 
1 148 ASP n 
1 149 TYR n 
1 150 PHE n 
1 151 PRO n 
1 152 GLU n 
1 153 PRO n 
1 154 VAL n 
1 155 THR n 
1 156 VAL n 
1 157 SER n 
1 158 TRP n 
1 159 ASN n 
1 160 SER n 
1 161 GLY n 
1 162 ALA n 
1 163 LEU n 
1 164 THR n 
1 165 SER n 
1 166 GLY n 
1 167 VAL n 
1 168 HIS n 
1 169 THR n 
1 170 PHE n 
1 171 PRO n 
1 172 ALA n 
1 173 VAL n 
1 174 LEU n 
1 175 GLN n 
1 176 SER n 
1 177 SER n 
1 178 GLY n 
1 179 LEU n 
1 180 TYR n 
1 181 SER n 
1 182 LEU n 
1 183 SER n 
1 184 SER n 
1 185 VAL n 
1 186 VAL n 
1 187 THR n 
1 188 VAL n 
1 189 PRO n 
1 190 SER n 
1 191 SER n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 THR n 
1 196 GLN n 
1 197 THR n 
1 198 TYR n 
1 199 ILE n 
1 200 CYS n 
1 201 ASN n 
1 202 VAL n 
1 203 ASN n 
1 204 HIS n 
1 205 LYS n 
1 206 PRO n 
1 207 SER n 
1 208 ASN n 
1 209 THR n 
1 210 LYS n 
1 211 VAL n 
1 212 ASP n 
1 213 LYS n 
1 214 LYS n 
1 215 VAL n 
1 216 GLU n 
1 217 PRO n 
1 218 LYS n 
1 219 SER n 
1 220 CYS n 
1 221 ASP n 
1 222 LYS n 
1 223 THR n 
1 224 HIS n 
1 225 THR n 
2 1   ASP n 
2 2   ILE n 
2 3   GLN n 
2 4   MET n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   SER n 
2 10  SER n 
2 11  LEU n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  VAL n 
2 16  GLY n 
2 17  ASP n 
2 18  ARG n 
2 19  VAL n 
2 20  THR n 
2 21  ILE n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  VAL n 
2 30  TRP n 
2 31  ARG n 
2 32  ASN n 
2 33  LYS n 
2 34  ASN n 
2 35  VAL n 
2 36  ALA n 
2 37  TRP n 
2 38  TYR n 
2 39  GLN n 
2 40  GLN n 
2 41  LYS n 
2 42  PRO n 
2 43  GLY n 
2 44  LYS n 
2 45  ALA n 
2 46  PRO n 
2 47  LYS n 
2 48  ARG n 
2 49  LEU n 
2 50  ILE n 
2 51  TYR n 
2 52  ALA n 
2 53  ILE n 
2 54  ALA n 
2 55  SER n 
2 56  LEU n 
2 57  TYR n 
2 58  SER n 
2 59  GLY n 
2 60  VAL n 
2 61  PRO n 
2 62  SER n 
2 63  ARG n 
2 64  PHE n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  SER n 
2 70  GLY n 
2 71  THR n 
2 72  ASP n 
2 73  PHE n 
2 74  THR n 
2 75  LEU n 
2 76  THR n 
2 77  ILE n 
2 78  SER n 
2 79  SER n 
2 80  LEU n 
2 81  GLN n 
2 82  PRO n 
2 83  GLU n 
2 84  ASP n 
2 85  PHE n 
2 86  ALA n 
2 87  THR n 
2 88  TYR n 
2 89  TYR n 
2 90  CYS n 
2 91  VAL n 
2 92  GLY n 
2 93  HIS n 
2 94  TYR n 
2 95  GLY n 
2 96  SER n 
2 97  GLU n 
2 98  ASN n 
2 99  ASP n 
2 100 ALA n 
2 101 TYR n 
2 102 TYR n 
2 103 ALA n 
2 104 PHE n 
2 105 GLY n 
2 106 GLN n 
2 107 GLY n 
2 108 THR n 
2 109 LYS n 
2 110 VAL n 
2 111 GLU n 
2 112 ILE n 
2 113 LYS n 
2 114 ARG n 
2 115 THR n 
2 116 VAL n 
2 117 ALA n 
2 118 ALA n 
2 119 PRO n 
2 120 SER n 
2 121 VAL n 
2 122 PHE n 
2 123 ILE n 
2 124 PHE n 
2 125 PRO n 
2 126 PRO n 
2 127 SER n 
2 128 ASP n 
2 129 GLU n 
2 130 GLN n 
2 131 LEU n 
2 132 LYS n 
2 133 SER n 
2 134 GLY n 
2 135 THR n 
2 136 ALA n 
2 137 SER n 
2 138 VAL n 
2 139 VAL n 
2 140 CYS n 
2 141 LEU n 
2 142 LEU n 
2 143 ASN n 
2 144 ASN n 
2 145 PHE n 
2 146 TYR n 
2 147 PRO n 
2 148 ARG n 
2 149 GLU n 
2 150 ALA n 
2 151 LYS n 
2 152 VAL n 
2 153 SER n 
2 154 TRP n 
2 155 TYR n 
2 156 VAL n 
2 157 ASP n 
2 158 ASN n 
2 159 ALA n 
2 160 LEU n 
2 161 GLN n 
2 162 SER n 
2 163 GLY n 
2 164 ASN n 
2 165 SER n 
2 166 GLN n 
2 167 GLU n 
2 168 SER n 
2 169 VAL n 
2 170 THR n 
2 171 GLU n 
2 172 GLN n 
2 173 ASP n 
2 174 SER n 
2 175 LYS n 
2 176 ASP n 
2 177 SER n 
2 178 THR n 
2 179 TYR n 
2 180 SER n 
2 181 LEU n 
2 182 SER n 
2 183 SER n 
2 184 THR n 
2 185 LEU n 
2 186 THR n 
2 187 LEU n 
2 188 SER n 
2 189 LYS n 
2 190 ALA n 
2 191 ASP n 
2 192 TYR n 
2 193 GLU n 
2 194 LYS n 
2 195 HIS n 
2 196 LYS n 
2 197 VAL n 
2 198 TYR n 
2 199 ALA n 
2 200 CYS n 
2 201 GLU n 
2 202 VAL n 
2 203 THR n 
2 204 GLN n 
2 205 GLY n 
2 206 THR n 
2 207 THR n 
2 208 SER n 
2 209 VAL n 
2 210 THR n 
2 211 LYS n 
2 212 SER n 
2 213 PHE n 
2 214 ASN n 
2 215 ARG n 
2 216 GLY n 
2 217 GLU n 
2 218 CYS n 
3 1   ALA n 
3 2   GLY n 
3 3   ALA n 
3 4   GLY n 
3 5   UKD n 
3 6   ALA n 
3 7   GLY n 
3 8   ALA n 
3 9   GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 225 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 218 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              3 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       9 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                           ?                 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                          ?                 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                        ?                 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                   ?                 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                          ?                 'C3 H7 N O2 S'   121.158 
EDO non-polymer         . 1,2-ETHANEDIOL                                    'ETHYLENE GLYCOL' 'C2 H6 O2'       62.068  
GLN 'L-peptide linking' y GLUTAMINE                                         ?                 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                   ?                 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                           ?                 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                         ?                 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                                             ?                 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE                                        ?                 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                           ?                 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                            ?                 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                        ?                 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                                     ?                 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                           ?                 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                            ?                 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                         ?                 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                        ?                 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                          ?                 'C9 H11 N O3'    181.189 
UKD 'L-peptide linking' . '3-(4-phosphono-1H-1,2,3-triazol-1-yl)-L-alanine' pHis              'C5 H9 N4 O5 P'  236.123 
VAL 'L-peptide linking' y VALINE                                            ?                 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  ARG 19  19  19  ARG ARG H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  THR 23  23  23  THR THR H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  ILE 29  29  29  ILE ILE H . n 
A 1 30  ASP 30  30  30  ASP ASP H . n 
A 1 31  SER 31  31  31  SER SER H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  GLY 33  33  33  GLY GLY H . n 
A 1 34  PHE 34  34  34  PHE PHE H . n 
A 1 35  SER 35  35  35  SER SER H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  ALA 40  40  40  ALA ALA H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  HIS 47  47  47  HIS HIS H . n 
A 1 48  ILE 48  48  48  ILE ILE H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  TYR 50  50  50  TYR TYR H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  THR 52  52  52  THR THR H . n 
A 1 53  ALA 53  53  53  ALA ALA H . n 
A 1 54  GLY 54  54  54  GLY GLY H . n 
A 1 55  GLY 55  55  55  GLY GLY H . n 
A 1 56  ARG 56  56  56  ARG ARG H . n 
A 1 57  ALA 57  57  57  ALA ALA H . n 
A 1 58  PHE 58  58  58  PHE PHE H . n 
A 1 59  TYR 59  59  59  TYR TYR H . n 
A 1 60  ALA 60  60  60  ALA ALA H . n 
A 1 61  SER 61  61  61  SER SER H . n 
A 1 62  TRP 62  62  62  TRP TRP H . n 
A 1 63  ALA 63  63  63  ALA ALA H . n 
A 1 64  LYS 64  64  64  LYS LYS H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  ARG 66  66  66  ARG ARG H . n 
A 1 67  SER 67  67  67  SER SER H . n 
A 1 68  THR 68  68  68  THR THR H . n 
A 1 69  ILE 69  69  69  ILE ILE H . n 
A 1 70  THR 70  70  70  THR THR H . n 
A 1 71  ARG 71  71  71  ARG ARG H . n 
A 1 72  ASN 72  72  72  ASN ASN H . n 
A 1 73  THR 73  73  73  THR THR H . n 
A 1 74  ASN 74  74  74  ASN ASN H . n 
A 1 75  GLU 75  75  75  GLU GLU H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  THR 77  77  77  THR THR H . n 
A 1 78  VAL 78  78  78  VAL VAL H . n 
A 1 79  THR 79  79  79  THR THR H . n 
A 1 80  LEU 80  80  80  LEU LEU H . n 
A 1 81  LYS 81  81  81  LYS LYS H . n 
A 1 82  MET 82  82  82  MET MET H . n 
A 1 83  ASN 83  82  82  ASN ASN H A n 
A 1 84  SER 84  82  82  SER SER H B n 
A 1 85  LEU 85  82  82  LEU LEU H C n 
A 1 86  ARG 86  83  83  ARG ARG H . n 
A 1 87  ALA 87  84  84  ALA ALA H . n 
A 1 88  GLU 88  85  85  GLU GLU H . n 
A 1 89  ASP 89  86  86  ASP ASP H . n 
A 1 90  THR 90  87  87  THR THR H . n 
A 1 91  ALA 91  88  88  ALA ALA H . n 
A 1 92  VAL 92  89  89  VAL VAL H . n 
A 1 93  TYR 93  90  90  TYR TYR H . n 
A 1 94  TYR 94  91  91  TYR TYR H . n 
A 1 95  CYS 95  92  92  CYS CYS H . n 
A 1 96  ALA 96  93  93  ALA ALA H . n 
A 1 97  LYS 97  94  94  LYS LYS H . n 
A 1 98  LEU 98  95  95  LEU LEU H . n 
A 1 99  GLY 99  96  96  GLY GLY H . n 
A 1 100 THR 100 97  97  THR THR H . n 
A 1 101 GLY 101 98  98  GLY GLY H . n 
A 1 102 SER 102 99  99  SER SER H . n 
A 1 103 ARG 103 100 100 ARG ARG H . n 
A 1 104 PHE 104 100 100 PHE PHE H A n 
A 1 105 ALA 105 101 101 ALA ALA H . n 
A 1 106 ILE 106 102 102 ILE ILE H . n 
A 1 107 TRP 107 103 103 TRP TRP H . n 
A 1 108 GLY 108 104 104 GLY GLY H . n 
A 1 109 GLN 109 105 105 GLN GLN H . n 
A 1 110 GLY 110 106 106 GLY GLY H . n 
A 1 111 THR 111 107 107 THR THR H . n 
A 1 112 LEU 112 108 108 LEU LEU H . n 
A 1 113 VAL 113 109 109 VAL VAL H . n 
A 1 114 THR 114 110 110 THR THR H . n 
A 1 115 VAL 115 111 111 VAL VAL H . n 
A 1 116 SER 116 112 112 SER SER H . n 
A 1 117 SER 117 113 113 SER SER H . n 
A 1 118 ALA 118 114 114 ALA ALA H . n 
A 1 119 SER 119 115 115 SER SER H . n 
A 1 120 THR 120 116 116 THR THR H . n 
A 1 121 LYS 121 117 117 LYS LYS H . n 
A 1 122 GLY 122 118 118 GLY GLY H . n 
A 1 123 PRO 123 119 119 PRO PRO H . n 
A 1 124 SER 124 120 120 SER SER H . n 
A 1 125 VAL 125 121 121 VAL VAL H . n 
A 1 126 PHE 126 122 122 PHE PHE H . n 
A 1 127 PRO 127 123 123 PRO PRO H . n 
A 1 128 LEU 128 124 124 LEU LEU H . n 
A 1 129 ALA 129 125 125 ALA ALA H . n 
A 1 130 PRO 130 126 126 PRO PRO H . n 
A 1 131 SER 131 127 127 SER SER H . n 
A 1 132 SER 132 128 128 SER SER H . n 
A 1 133 LYS 133 129 129 LYS LYS H . n 
A 1 134 SER 134 130 130 SER SER H . n 
A 1 135 THR 135 131 131 THR THR H . n 
A 1 136 SER 136 132 132 SER SER H . n 
A 1 137 GLY 137 133 133 GLY GLY H . n 
A 1 138 GLY 138 134 134 GLY GLY H . n 
A 1 139 THR 139 135 135 THR THR H . n 
A 1 140 ALA 140 136 136 ALA ALA H . n 
A 1 141 ALA 141 137 137 ALA ALA H . n 
A 1 142 LEU 142 138 138 LEU LEU H . n 
A 1 143 GLY 143 139 139 GLY GLY H . n 
A 1 144 CYS 144 140 140 CYS CYS H . n 
A 1 145 LEU 145 141 141 LEU LEU H . n 
A 1 146 VAL 146 142 142 VAL VAL H . n 
A 1 147 LYS 147 143 143 LYS LYS H . n 
A 1 148 ASP 148 144 144 ASP ASP H . n 
A 1 149 TYR 149 145 145 TYR TYR H . n 
A 1 150 PHE 150 146 146 PHE PHE H . n 
A 1 151 PRO 151 147 147 PRO PRO H . n 
A 1 152 GLU 152 148 148 GLU GLU H . n 
A 1 153 PRO 153 149 149 PRO PRO H . n 
A 1 154 VAL 154 150 150 VAL VAL H . n 
A 1 155 THR 155 151 151 THR THR H . n 
A 1 156 VAL 156 152 152 VAL VAL H . n 
A 1 157 SER 157 153 153 SER SER H . n 
A 1 158 TRP 158 154 154 TRP TRP H . n 
A 1 159 ASN 159 155 155 ASN ASN H . n 
A 1 160 SER 160 156 156 SER SER H . n 
A 1 161 GLY 161 157 157 GLY GLY H . n 
A 1 162 ALA 162 158 158 ALA ALA H . n 
A 1 163 LEU 163 159 159 LEU LEU H . n 
A 1 164 THR 164 160 160 THR THR H . n 
A 1 165 SER 165 161 161 SER SER H . n 
A 1 166 GLY 166 162 162 GLY GLY H . n 
A 1 167 VAL 167 163 163 VAL VAL H . n 
A 1 168 HIS 168 164 164 HIS HIS H . n 
A 1 169 THR 169 165 165 THR THR H . n 
A 1 170 PHE 170 166 166 PHE PHE H . n 
A 1 171 PRO 171 167 167 PRO PRO H . n 
A 1 172 ALA 172 168 168 ALA ALA H . n 
A 1 173 VAL 173 169 169 VAL VAL H . n 
A 1 174 LEU 174 170 170 LEU LEU H . n 
A 1 175 GLN 175 171 171 GLN GLN H . n 
A 1 176 SER 176 172 172 SER SER H . n 
A 1 177 SER 177 173 173 SER SER H . n 
A 1 178 GLY 178 174 174 GLY GLY H . n 
A 1 179 LEU 179 175 175 LEU LEU H . n 
A 1 180 TYR 180 176 176 TYR TYR H . n 
A 1 181 SER 181 177 177 SER SER H . n 
A 1 182 LEU 182 178 178 LEU LEU H . n 
A 1 183 SER 183 179 179 SER SER H . n 
A 1 184 SER 184 180 180 SER SER H . n 
A 1 185 VAL 185 181 181 VAL VAL H . n 
A 1 186 VAL 186 182 182 VAL VAL H . n 
A 1 187 THR 187 183 183 THR THR H . n 
A 1 188 VAL 188 184 184 VAL VAL H . n 
A 1 189 PRO 189 185 185 PRO PRO H . n 
A 1 190 SER 190 186 186 SER SER H . n 
A 1 191 SER 191 187 187 SER SER H . n 
A 1 192 SER 192 188 188 SER SER H . n 
A 1 193 LEU 193 189 189 LEU LEU H . n 
A 1 194 GLY 194 190 190 GLY GLY H . n 
A 1 195 THR 195 191 191 THR THR H . n 
A 1 196 GLN 196 192 192 GLN GLN H . n 
A 1 197 THR 197 193 193 THR THR H . n 
A 1 198 TYR 198 194 194 TYR TYR H . n 
A 1 199 ILE 199 195 195 ILE ILE H . n 
A 1 200 CYS 200 196 196 CYS CYS H . n 
A 1 201 ASN 201 197 197 ASN ASN H . n 
A 1 202 VAL 202 198 198 VAL VAL H . n 
A 1 203 ASN 203 199 199 ASN ASN H . n 
A 1 204 HIS 204 200 200 HIS HIS H . n 
A 1 205 LYS 205 201 201 LYS LYS H . n 
A 1 206 PRO 206 202 202 PRO PRO H . n 
A 1 207 SER 207 203 203 SER SER H . n 
A 1 208 ASN 208 204 204 ASN ASN H . n 
A 1 209 THR 209 205 205 THR THR H . n 
A 1 210 LYS 210 206 206 LYS LYS H . n 
A 1 211 VAL 211 207 207 VAL VAL H . n 
A 1 212 ASP 212 208 208 ASP ASP H . n 
A 1 213 LYS 213 209 209 LYS LYS H . n 
A 1 214 LYS 214 210 210 LYS LYS H . n 
A 1 215 VAL 215 211 211 VAL VAL H . n 
A 1 216 GLU 216 212 212 GLU GLU H . n 
A 1 217 PRO 217 213 213 PRO PRO H . n 
A 1 218 LYS 218 214 214 LYS LYS H . n 
A 1 219 SER 219 215 ?   ?   ?   H . n 
A 1 220 CYS 220 216 ?   ?   ?   H . n 
A 1 221 ASP 221 217 ?   ?   ?   H . n 
A 1 222 LYS 222 218 ?   ?   ?   H . n 
A 1 223 THR 223 219 ?   ?   ?   H . n 
A 1 224 HIS 224 220 ?   ?   ?   H . n 
A 1 225 THR 225 221 ?   ?   ?   H . n 
B 2 1   ASP 1   1   1   ASP ASP L . n 
B 2 2   ILE 2   2   2   ILE ILE L . n 
B 2 3   GLN 3   3   3   GLN GLN L . n 
B 2 4   MET 4   4   4   MET MET L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   SER 9   9   9   SER SER L . n 
B 2 10  SER 10  10  10  SER SER L . n 
B 2 11  LEU 11  11  11  LEU LEU L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  VAL 15  15  15  VAL VAL L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  ASP 17  17  17  ASP ASP L . n 
B 2 18  ARG 18  18  18  ARG ARG L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  ILE 21  21  21  ILE ILE L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  GLN 27  27  27  GLN GLN L . n 
B 2 28  SER 28  27  27  SER SER L A n 
B 2 29  VAL 29  27  27  VAL VAL L B n 
B 2 30  TRP 30  28  28  TRP TRP L . n 
B 2 31  ARG 31  29  29  ARG ARG L . n 
B 2 32  ASN 32  30  30  ASN ASN L . n 
B 2 33  LYS 33  31  31  LYS LYS L . n 
B 2 34  ASN 34  32  32  ASN ASN L . n 
B 2 35  VAL 35  33  33  VAL VAL L . n 
B 2 36  ALA 36  34  34  ALA ALA L . n 
B 2 37  TRP 37  35  35  TRP TRP L . n 
B 2 38  TYR 38  36  36  TYR TYR L . n 
B 2 39  GLN 39  37  37  GLN GLN L . n 
B 2 40  GLN 40  38  38  GLN GLN L . n 
B 2 41  LYS 41  39  39  LYS LYS L . n 
B 2 42  PRO 42  40  40  PRO PRO L . n 
B 2 43  GLY 43  41  41  GLY GLY L . n 
B 2 44  LYS 44  42  42  LYS LYS L . n 
B 2 45  ALA 45  43  43  ALA ALA L . n 
B 2 46  PRO 46  44  44  PRO PRO L . n 
B 2 47  LYS 47  45  45  LYS LYS L . n 
B 2 48  ARG 48  46  46  ARG ARG L . n 
B 2 49  LEU 49  47  47  LEU LEU L . n 
B 2 50  ILE 50  48  48  ILE ILE L . n 
B 2 51  TYR 51  49  49  TYR TYR L . n 
B 2 52  ALA 52  50  50  ALA ALA L . n 
B 2 53  ILE 53  51  51  ILE ILE L . n 
B 2 54  ALA 54  52  52  ALA ALA L . n 
B 2 55  SER 55  53  53  SER SER L . n 
B 2 56  LEU 56  54  54  LEU LEU L . n 
B 2 57  TYR 57  55  55  TYR TYR L . n 
B 2 58  SER 58  56  56  SER SER L . n 
B 2 59  GLY 59  57  57  GLY GLY L . n 
B 2 60  VAL 60  58  58  VAL VAL L . n 
B 2 61  PRO 61  59  59  PRO PRO L . n 
B 2 62  SER 62  60  60  SER SER L . n 
B 2 63  ARG 63  61  61  ARG ARG L . n 
B 2 64  PHE 64  62  62  PHE PHE L . n 
B 2 65  SER 65  63  63  SER SER L . n 
B 2 66  GLY 66  64  64  GLY GLY L . n 
B 2 67  SER 67  65  65  SER SER L . n 
B 2 68  GLY 68  66  66  GLY GLY L . n 
B 2 69  SER 69  67  67  SER SER L . n 
B 2 70  GLY 70  68  68  GLY GLY L . n 
B 2 71  THR 71  69  69  THR THR L . n 
B 2 72  ASP 72  70  70  ASP ASP L . n 
B 2 73  PHE 73  71  71  PHE PHE L . n 
B 2 74  THR 74  72  72  THR THR L . n 
B 2 75  LEU 75  73  73  LEU LEU L . n 
B 2 76  THR 76  74  74  THR THR L . n 
B 2 77  ILE 77  75  75  ILE ILE L . n 
B 2 78  SER 78  76  76  SER SER L . n 
B 2 79  SER 79  77  77  SER SER L . n 
B 2 80  LEU 80  78  78  LEU LEU L . n 
B 2 81  GLN 81  79  79  GLN GLN L . n 
B 2 82  PRO 82  80  80  PRO PRO L . n 
B 2 83  GLU 83  81  81  GLU GLU L . n 
B 2 84  ASP 84  82  82  ASP ASP L . n 
B 2 85  PHE 85  83  83  PHE PHE L . n 
B 2 86  ALA 86  84  84  ALA ALA L . n 
B 2 87  THR 87  85  85  THR THR L . n 
B 2 88  TYR 88  86  86  TYR TYR L . n 
B 2 89  TYR 89  87  87  TYR TYR L . n 
B 2 90  CYS 90  88  88  CYS CYS L . n 
B 2 91  VAL 91  89  89  VAL VAL L . n 
B 2 92  GLY 92  90  90  GLY GLY L . n 
B 2 93  HIS 93  91  91  HIS HIS L . n 
B 2 94  TYR 94  92  92  TYR TYR L . n 
B 2 95  GLY 95  93  93  GLY GLY L . n 
B 2 96  SER 96  94  94  SER SER L . n 
B 2 97  GLU 97  95  95  GLU GLU L . n 
B 2 98  ASN 98  95  95  ASN ASN L A n 
B 2 99  ASP 99  95  95  ASP ASP L B n 
B 2 100 ALA 100 95  95  ALA ALA L C n 
B 2 101 TYR 101 95  95  TYR TYR L D n 
B 2 102 TYR 102 96  96  TYR TYR L . n 
B 2 103 ALA 103 97  97  ALA ALA L . n 
B 2 104 PHE 104 98  98  PHE PHE L . n 
B 2 105 GLY 105 99  99  GLY GLY L . n 
B 2 106 GLN 106 100 100 GLN GLN L . n 
B 2 107 GLY 107 101 101 GLY GLY L . n 
B 2 108 THR 108 102 102 THR THR L . n 
B 2 109 LYS 109 103 103 LYS LYS L . n 
B 2 110 VAL 110 104 104 VAL VAL L . n 
B 2 111 GLU 111 105 105 GLU GLU L . n 
B 2 112 ILE 112 106 106 ILE ILE L . n 
B 2 113 LYS 113 107 107 LYS LYS L . n 
B 2 114 ARG 114 108 108 ARG ARG L . n 
B 2 115 THR 115 109 109 THR THR L . n 
B 2 116 VAL 116 110 110 VAL VAL L . n 
B 2 117 ALA 117 111 111 ALA ALA L . n 
B 2 118 ALA 118 112 112 ALA ALA L . n 
B 2 119 PRO 119 113 113 PRO PRO L . n 
B 2 120 SER 120 114 114 SER SER L . n 
B 2 121 VAL 121 115 115 VAL VAL L . n 
B 2 122 PHE 122 116 116 PHE PHE L . n 
B 2 123 ILE 123 117 117 ILE ILE L . n 
B 2 124 PHE 124 118 118 PHE PHE L . n 
B 2 125 PRO 125 119 119 PRO PRO L . n 
B 2 126 PRO 126 120 120 PRO PRO L . n 
B 2 127 SER 127 121 121 SER SER L . n 
B 2 128 ASP 128 122 122 ASP ASP L . n 
B 2 129 GLU 129 123 123 GLU GLU L . n 
B 2 130 GLN 130 124 124 GLN GLN L . n 
B 2 131 LEU 131 125 125 LEU LEU L . n 
B 2 132 LYS 132 126 126 LYS LYS L . n 
B 2 133 SER 133 127 127 SER SER L . n 
B 2 134 GLY 134 128 128 GLY GLY L . n 
B 2 135 THR 135 129 129 THR THR L . n 
B 2 136 ALA 136 130 130 ALA ALA L . n 
B 2 137 SER 137 131 131 SER SER L . n 
B 2 138 VAL 138 132 132 VAL VAL L . n 
B 2 139 VAL 139 133 133 VAL VAL L . n 
B 2 140 CYS 140 134 134 CYS CYS L . n 
B 2 141 LEU 141 135 135 LEU LEU L . n 
B 2 142 LEU 142 136 136 LEU LEU L . n 
B 2 143 ASN 143 137 137 ASN ASN L . n 
B 2 144 ASN 144 138 138 ASN ASN L . n 
B 2 145 PHE 145 139 139 PHE PHE L . n 
B 2 146 TYR 146 140 140 TYR TYR L . n 
B 2 147 PRO 147 141 141 PRO PRO L . n 
B 2 148 ARG 148 142 142 ARG ARG L . n 
B 2 149 GLU 149 143 143 GLU GLU L . n 
B 2 150 ALA 150 144 144 ALA ALA L . n 
B 2 151 LYS 151 145 145 LYS LYS L . n 
B 2 152 VAL 152 146 146 VAL VAL L . n 
B 2 153 SER 153 147 147 SER SER L . n 
B 2 154 TRP 154 148 148 TRP TRP L . n 
B 2 155 TYR 155 149 149 TYR TYR L . n 
B 2 156 VAL 156 150 150 VAL VAL L . n 
B 2 157 ASP 157 151 151 ASP ASP L . n 
B 2 158 ASN 158 152 152 ASN ASN L . n 
B 2 159 ALA 159 153 153 ALA ALA L . n 
B 2 160 LEU 160 154 154 LEU LEU L . n 
B 2 161 GLN 161 155 155 GLN GLN L . n 
B 2 162 SER 162 156 156 SER SER L . n 
B 2 163 GLY 163 157 157 GLY GLY L . n 
B 2 164 ASN 164 158 158 ASN ASN L . n 
B 2 165 SER 165 159 159 SER SER L . n 
B 2 166 GLN 166 160 160 GLN GLN L . n 
B 2 167 GLU 167 161 161 GLU GLU L . n 
B 2 168 SER 168 162 162 SER SER L . n 
B 2 169 VAL 169 163 163 VAL VAL L . n 
B 2 170 THR 170 164 164 THR THR L . n 
B 2 171 GLU 171 165 165 GLU GLU L . n 
B 2 172 GLN 172 166 166 GLN GLN L . n 
B 2 173 ASP 173 167 167 ASP ASP L . n 
B 2 174 SER 174 168 168 SER SER L . n 
B 2 175 LYS 175 169 169 LYS LYS L . n 
B 2 176 ASP 176 170 170 ASP ASP L . n 
B 2 177 SER 177 171 171 SER SER L . n 
B 2 178 THR 178 172 172 THR THR L . n 
B 2 179 TYR 179 173 173 TYR TYR L . n 
B 2 180 SER 180 174 174 SER SER L . n 
B 2 181 LEU 181 175 175 LEU LEU L . n 
B 2 182 SER 182 176 176 SER SER L . n 
B 2 183 SER 183 177 177 SER SER L . n 
B 2 184 THR 184 178 178 THR THR L . n 
B 2 185 LEU 185 179 179 LEU LEU L . n 
B 2 186 THR 186 180 180 THR THR L . n 
B 2 187 LEU 187 181 181 LEU LEU L . n 
B 2 188 SER 188 182 182 SER SER L . n 
B 2 189 LYS 189 183 183 LYS LYS L . n 
B 2 190 ALA 190 184 184 ALA ALA L . n 
B 2 191 ASP 191 185 185 ASP ASP L . n 
B 2 192 TYR 192 186 186 TYR TYR L . n 
B 2 193 GLU 193 187 187 GLU GLU L . n 
B 2 194 LYS 194 188 188 LYS LYS L . n 
B 2 195 HIS 195 189 189 HIS HIS L . n 
B 2 196 LYS 196 190 190 LYS LYS L . n 
B 2 197 VAL 197 191 191 VAL VAL L . n 
B 2 198 TYR 198 192 192 TYR TYR L . n 
B 2 199 ALA 199 193 193 ALA ALA L . n 
B 2 200 CYS 200 194 194 CYS CYS L . n 
B 2 201 GLU 201 195 195 GLU GLU L . n 
B 2 202 VAL 202 196 196 VAL VAL L . n 
B 2 203 THR 203 197 197 THR THR L . n 
B 2 204 GLN 204 198 198 GLN GLN L . n 
B 2 205 GLY 205 199 199 GLY GLY L . n 
B 2 206 THR 206 200 200 THR THR L . n 
B 2 207 THR 207 201 201 THR THR L . n 
B 2 208 SER 208 202 202 SER SER L . n 
B 2 209 VAL 209 203 203 VAL VAL L . n 
B 2 210 THR 210 204 204 THR THR L . n 
B 2 211 LYS 211 205 205 LYS LYS L . n 
B 2 212 SER 212 206 206 SER SER L . n 
B 2 213 PHE 213 207 207 PHE PHE L . n 
B 2 214 ASN 214 208 208 ASN ASN L . n 
B 2 215 ARG 215 209 209 ARG ARG L . n 
B 2 216 GLY 216 210 210 GLY GLY L . n 
B 2 217 GLU 217 211 211 GLU GLU L . n 
B 2 218 CYS 218 212 212 CYS CYS L . n 
C 3 1   ALA 1   1   ?   ?   ?   D . n 
C 3 2   GLY 2   2   ?   ?   ?   D . n 
C 3 3   ALA 3   3   3   ALA ALA D . n 
C 3 4   GLY 4   4   4   GLY GLY D . n 
C 3 5   UKD 5   5   5   UKD UNK D . n 
C 3 6   ALA 6   6   6   ALA ALA D . n 
C 3 7   GLY 7   7   7   GLY GLY D . n 
C 3 8   ALA 8   8   8   ALA ALA D . n 
C 3 9   GLY 9   9   ?   ?   ?   D . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 EDO 1   301 308 EDO EDO H . 
E 4 EDO 1   301 302 EDO EDO L . 
F 5 HOH 1   401 328 HOH HOH H . 
F 5 HOH 2   402 329 HOH HOH H . 
F 5 HOH 3   403 327 HOH HOH H . 
F 5 HOH 4   404 20  HOH HOH H . 
F 5 HOH 5   405 343 HOH HOH H . 
F 5 HOH 6   406 126 HOH HOH H . 
F 5 HOH 7   407 115 HOH HOH H . 
F 5 HOH 8   408 326 HOH HOH H . 
F 5 HOH 9   409 113 HOH HOH H . 
F 5 HOH 10  410 17  HOH HOH H . 
F 5 HOH 11  411 244 HOH HOH H . 
F 5 HOH 12  412 178 HOH HOH H . 
F 5 HOH 13  413 97  HOH HOH H . 
F 5 HOH 14  414 12  HOH HOH H . 
F 5 HOH 15  415 78  HOH HOH H . 
F 5 HOH 16  416 283 HOH HOH H . 
F 5 HOH 17  417 1   HOH HOH H . 
F 5 HOH 18  418 32  HOH HOH H . 
F 5 HOH 19  419 15  HOH HOH H . 
F 5 HOH 20  420 350 HOH HOH H . 
F 5 HOH 21  421 105 HOH HOH H . 
F 5 HOH 22  422 158 HOH HOH H . 
F 5 HOH 23  423 64  HOH HOH H . 
F 5 HOH 24  424 84  HOH HOH H . 
F 5 HOH 25  425 174 HOH HOH H . 
F 5 HOH 26  426 35  HOH HOH H . 
F 5 HOH 27  427 110 HOH HOH H . 
F 5 HOH 28  428 268 HOH HOH H . 
F 5 HOH 29  429 101 HOH HOH H . 
F 5 HOH 30  430 83  HOH HOH H . 
F 5 HOH 31  431 6   HOH HOH H . 
F 5 HOH 32  432 75  HOH HOH H . 
F 5 HOH 33  433 229 HOH HOH H . 
F 5 HOH 34  434 164 HOH HOH H . 
F 5 HOH 35  435 142 HOH HOH H . 
F 5 HOH 36  436 90  HOH HOH H . 
F 5 HOH 37  437 191 HOH HOH H . 
F 5 HOH 38  438 313 HOH HOH H . 
F 5 HOH 39  439 129 HOH HOH H . 
F 5 HOH 40  440 7   HOH HOH H . 
F 5 HOH 41  441 86  HOH HOH H . 
F 5 HOH 42  442 284 HOH HOH H . 
F 5 HOH 43  443 28  HOH HOH H . 
F 5 HOH 44  444 100 HOH HOH H . 
F 5 HOH 45  445 102 HOH HOH H . 
F 5 HOH 46  446 144 HOH HOH H . 
F 5 HOH 47  447 10  HOH HOH H . 
F 5 HOH 48  448 11  HOH HOH H . 
F 5 HOH 49  449 353 HOH HOH H . 
F 5 HOH 50  450 160 HOH HOH H . 
F 5 HOH 51  451 173 HOH HOH H . 
F 5 HOH 52  452 112 HOH HOH H . 
F 5 HOH 53  453 109 HOH HOH H . 
F 5 HOH 54  454 188 HOH HOH H . 
F 5 HOH 55  455 233 HOH HOH H . 
F 5 HOH 56  456 186 HOH HOH H . 
F 5 HOH 57  457 87  HOH HOH H . 
F 5 HOH 58  458 104 HOH HOH H . 
F 5 HOH 59  459 150 HOH HOH H . 
F 5 HOH 60  460 192 HOH HOH H . 
F 5 HOH 61  461 153 HOH HOH H . 
F 5 HOH 62  462 98  HOH HOH H . 
F 5 HOH 63  463 176 HOH HOH H . 
F 5 HOH 64  464 77  HOH HOH H . 
F 5 HOH 65  465 122 HOH HOH H . 
F 5 HOH 66  466 127 HOH HOH H . 
F 5 HOH 67  467 76  HOH HOH H . 
F 5 HOH 68  468 60  HOH HOH H . 
F 5 HOH 69  469 308 HOH HOH H . 
F 5 HOH 70  470 24  HOH HOH H . 
F 5 HOH 71  471 317 HOH HOH H . 
F 5 HOH 72  472 351 HOH HOH H . 
F 5 HOH 73  473 58  HOH HOH H . 
F 5 HOH 74  474 187 HOH HOH H . 
F 5 HOH 75  475 46  HOH HOH H . 
F 5 HOH 76  476 81  HOH HOH H . 
F 5 HOH 77  477 39  HOH HOH H . 
F 5 HOH 78  478 306 HOH HOH H . 
F 5 HOH 79  479 121 HOH HOH H . 
F 5 HOH 80  480 269 HOH HOH H . 
F 5 HOH 81  481 111 HOH HOH H . 
F 5 HOH 82  482 194 HOH HOH H . 
F 5 HOH 83  483 251 HOH HOH H . 
F 5 HOH 84  484 184 HOH HOH H . 
F 5 HOH 85  485 242 HOH HOH H . 
F 5 HOH 86  486 25  HOH HOH H . 
F 5 HOH 87  487 216 HOH HOH H . 
F 5 HOH 88  488 34  HOH HOH H . 
F 5 HOH 89  489 54  HOH HOH H . 
F 5 HOH 90  490 238 HOH HOH H . 
F 5 HOH 91  491 106 HOH HOH H . 
F 5 HOH 92  492 287 HOH HOH H . 
F 5 HOH 93  493 49  HOH HOH H . 
F 5 HOH 94  494 141 HOH HOH H . 
F 5 HOH 95  495 33  HOH HOH H . 
F 5 HOH 96  496 137 HOH HOH H . 
F 5 HOH 97  497 344 HOH HOH H . 
F 5 HOH 98  498 135 HOH HOH H . 
F 5 HOH 99  499 36  HOH HOH H . 
F 5 HOH 100 500 298 HOH HOH H . 
F 5 HOH 101 501 123 HOH HOH H . 
F 5 HOH 102 502 175 HOH HOH H . 
F 5 HOH 103 503 107 HOH HOH H . 
F 5 HOH 104 504 311 HOH HOH H . 
F 5 HOH 105 505 332 HOH HOH H . 
F 5 HOH 106 506 88  HOH HOH H . 
F 5 HOH 107 507 198 HOH HOH H . 
F 5 HOH 108 508 323 HOH HOH H . 
F 5 HOH 109 509 128 HOH HOH H . 
F 5 HOH 110 510 68  HOH HOH H . 
F 5 HOH 111 511 339 HOH HOH H . 
F 5 HOH 112 512 209 HOH HOH H . 
F 5 HOH 113 513 177 HOH HOH H . 
F 5 HOH 114 514 347 HOH HOH H . 
F 5 HOH 115 515 296 HOH HOH H . 
F 5 HOH 116 516 228 HOH HOH H . 
F 5 HOH 117 517 335 HOH HOH H . 
F 5 HOH 118 518 316 HOH HOH H . 
F 5 HOH 119 519 155 HOH HOH H . 
F 5 HOH 120 520 201 HOH HOH H . 
F 5 HOH 121 521 260 HOH HOH H . 
F 5 HOH 122 522 225 HOH HOH H . 
F 5 HOH 123 523 299 HOH HOH H . 
F 5 HOH 124 524 285 HOH HOH H . 
F 5 HOH 125 525 261 HOH HOH H . 
F 5 HOH 126 526 149 HOH HOH H . 
F 5 HOH 127 527 116 HOH HOH H . 
F 5 HOH 128 528 255 HOH HOH H . 
G 5 HOH 1   401 279 HOH HOH L . 
G 5 HOH 2   402 348 HOH HOH L . 
G 5 HOH 3   403 66  HOH HOH L . 
G 5 HOH 4   404 161 HOH HOH L . 
G 5 HOH 5   405 47  HOH HOH L . 
G 5 HOH 6   406 250 HOH HOH L . 
G 5 HOH 7   407 322 HOH HOH L . 
G 5 HOH 8   408 148 HOH HOH L . 
G 5 HOH 9   409 219 HOH HOH L . 
G 5 HOH 10  410 270 HOH HOH L . 
G 5 HOH 11  411 114 HOH HOH L . 
G 5 HOH 12  412 23  HOH HOH L . 
G 5 HOH 13  413 117 HOH HOH L . 
G 5 HOH 14  414 45  HOH HOH L . 
G 5 HOH 15  415 165 HOH HOH L . 
G 5 HOH 16  416 3   HOH HOH L . 
G 5 HOH 17  417 340 HOH HOH L . 
G 5 HOH 18  418 4   HOH HOH L . 
G 5 HOH 19  419 206 HOH HOH L . 
G 5 HOH 20  420 44  HOH HOH L . 
G 5 HOH 21  421 288 HOH HOH L . 
G 5 HOH 22  422 2   HOH HOH L . 
G 5 HOH 23  423 314 HOH HOH L . 
G 5 HOH 24  424 301 HOH HOH L . 
G 5 HOH 25  425 182 HOH HOH L . 
G 5 HOH 26  426 325 HOH HOH L . 
G 5 HOH 27  427 281 HOH HOH L . 
G 5 HOH 28  428 169 HOH HOH L . 
G 5 HOH 29  429 71  HOH HOH L . 
G 5 HOH 30  430 8   HOH HOH L . 
G 5 HOH 31  431 14  HOH HOH L . 
G 5 HOH 32  432 221 HOH HOH L . 
G 5 HOH 33  433 154 HOH HOH L . 
G 5 HOH 34  434 85  HOH HOH L . 
G 5 HOH 35  435 304 HOH HOH L . 
G 5 HOH 36  436 29  HOH HOH L . 
G 5 HOH 37  437 303 HOH HOH L . 
G 5 HOH 38  438 37  HOH HOH L . 
G 5 HOH 39  439 338 HOH HOH L . 
G 5 HOH 40  440 185 HOH HOH L . 
G 5 HOH 41  441 146 HOH HOH L . 
G 5 HOH 42  442 349 HOH HOH L . 
G 5 HOH 43  443 170 HOH HOH L . 
G 5 HOH 44  444 157 HOH HOH L . 
G 5 HOH 45  445 96  HOH HOH L . 
G 5 HOH 46  446 18  HOH HOH L . 
G 5 HOH 47  447 119 HOH HOH L . 
G 5 HOH 48  448 189 HOH HOH L . 
G 5 HOH 49  449 275 HOH HOH L . 
G 5 HOH 50  450 59  HOH HOH L . 
G 5 HOH 51  451 50  HOH HOH L . 
G 5 HOH 52  452 125 HOH HOH L . 
G 5 HOH 53  453 352 HOH HOH L . 
G 5 HOH 54  454 79  HOH HOH L . 
G 5 HOH 55  455 147 HOH HOH L . 
G 5 HOH 56  456 91  HOH HOH L . 
G 5 HOH 57  457 318 HOH HOH L . 
G 5 HOH 58  458 51  HOH HOH L . 
G 5 HOH 59  459 42  HOH HOH L . 
G 5 HOH 60  460 134 HOH HOH L . 
G 5 HOH 61  461 95  HOH HOH L . 
G 5 HOH 62  462 220 HOH HOH L . 
G 5 HOH 63  463 156 HOH HOH L . 
G 5 HOH 64  464 93  HOH HOH L . 
G 5 HOH 65  465 52  HOH HOH L . 
G 5 HOH 66  466 151 HOH HOH L . 
G 5 HOH 67  467 56  HOH HOH L . 
G 5 HOH 68  468 38  HOH HOH L . 
G 5 HOH 69  469 80  HOH HOH L . 
G 5 HOH 70  470 99  HOH HOH L . 
G 5 HOH 71  471 63  HOH HOH L . 
G 5 HOH 72  472 300 HOH HOH L . 
G 5 HOH 73  473 70  HOH HOH L . 
G 5 HOH 74  474 5   HOH HOH L . 
G 5 HOH 75  475 55  HOH HOH L . 
G 5 HOH 76  476 291 HOH HOH L . 
G 5 HOH 77  477 48  HOH HOH L . 
G 5 HOH 78  478 345 HOH HOH L . 
G 5 HOH 79  479 103 HOH HOH L . 
G 5 HOH 80  480 274 HOH HOH L . 
G 5 HOH 81  481 240 HOH HOH L . 
G 5 HOH 82  482 133 HOH HOH L . 
G 5 HOH 83  483 183 HOH HOH L . 
G 5 HOH 84  484 265 HOH HOH L . 
G 5 HOH 85  485 292 HOH HOH L . 
G 5 HOH 86  486 132 HOH HOH L . 
G 5 HOH 87  487 152 HOH HOH L . 
G 5 HOH 88  488 290 HOH HOH L . 
G 5 HOH 89  489 67  HOH HOH L . 
G 5 HOH 90  490 276 HOH HOH L . 
G 5 HOH 91  491 13  HOH HOH L . 
G 5 HOH 92  492 204 HOH HOH L . 
G 5 HOH 93  493 16  HOH HOH L . 
G 5 HOH 94  494 200 HOH HOH L . 
G 5 HOH 95  495 341 HOH HOH L . 
G 5 HOH 96  496 27  HOH HOH L . 
G 5 HOH 97  497 190 HOH HOH L . 
G 5 HOH 98  498 138 HOH HOH L . 
G 5 HOH 99  499 282 HOH HOH L . 
G 5 HOH 100 500 130 HOH HOH L . 
G 5 HOH 101 501 319 HOH HOH L . 
G 5 HOH 102 502 61  HOH HOH L . 
G 5 HOH 103 503 293 HOH HOH L . 
G 5 HOH 104 504 57  HOH HOH L . 
G 5 HOH 105 505 181 HOH HOH L . 
G 5 HOH 106 506 159 HOH HOH L . 
G 5 HOH 107 507 136 HOH HOH L . 
G 5 HOH 108 508 120 HOH HOH L . 
G 5 HOH 109 509 237 HOH HOH L . 
G 5 HOH 110 510 245 HOH HOH L . 
G 5 HOH 111 511 30  HOH HOH L . 
G 5 HOH 112 512 203 HOH HOH L . 
G 5 HOH 113 513 262 HOH HOH L . 
G 5 HOH 114 514 295 HOH HOH L . 
G 5 HOH 115 515 337 HOH HOH L . 
G 5 HOH 116 516 315 HOH HOH L . 
G 5 HOH 117 517 294 HOH HOH L . 
G 5 HOH 118 518 302 HOH HOH L . 
G 5 HOH 119 519 246 HOH HOH L . 
G 5 HOH 120 520 289 HOH HOH L . 
G 5 HOH 121 521 330 HOH HOH L . 
G 5 HOH 122 522 232 HOH HOH L . 
G 5 HOH 123 523 346 HOH HOH L . 
G 5 HOH 124 524 336 HOH HOH L . 
G 5 HOH 125 525 212 HOH HOH L . 
G 5 HOH 126 526 218 HOH HOH L . 
G 5 HOH 127 527 305 HOH HOH L . 
G 5 HOH 128 528 243 HOH HOH L . 
G 5 HOH 129 529 280 HOH HOH L . 
G 5 HOH 130 530 227 HOH HOH L . 
H 5 HOH 1   101 213 HOH HOH D . 
H 5 HOH 2   102 69  HOH HOH D . 
H 5 HOH 3   103 72  HOH HOH D . 
H 5 HOH 4   104 168 HOH HOH D . 
H 5 HOH 5   105 333 HOH HOH D . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   111.244 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UIH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     79.958 
_cell.length_a_esd                 ? 
_cell.length_b                     73.115 
_cell.length_b_esd                 ? 
_cell.length_c                     88.071 
_cell.length_c_esd                 ? 
_cell.volume                       479886.571 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UIH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            'C 2y' 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UIH 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.49 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          50.69 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M tri-potassium citrate, 20% PEG3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-04-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.03320 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 23-ID-D' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.03320 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   23-ID-D 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          22.27 
_reflns.entry_id                                       8UIH 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.85 
_reflns.d_resolution_low                               41.04 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     40163 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     0.0 
_reflns.observed_criterion_sigma_I                     -3.0 
_reflns.percent_possible_obs                           99.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.001 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.151 
_reflns.pdbx_Rpim_I_all                                0.074 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.991 
_reflns.pdbx_CC_star                                   0.998 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.131 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                0.131 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.85 
_reflns_shell.d_res_low                                     1.88 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           0.98 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1984 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.3 
_reflns_shell.pdbx_chi_squared                              0.96 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.51 
_reflns_shell.pdbx_Rpim_I_all                               0.79 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.362 
_reflns_shell.pdbx_CC_star                                  0.729 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.4 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.28 
_reflns_shell.pdbx_Rsym_value                               1.28 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               28.97 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UIH 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.85 
_refine.ls_d_res_low                             41.04 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     40152 
_refine.ls_number_reflns_R_free                  1978 
_refine.ls_number_reflns_R_work                  38174 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.28 
_refine.ls_percent_reflns_R_free                 4.93 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2069 
_refine.ls_R_factor_R_free                       0.2434 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2050 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.0275 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2842 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.85 
_refine_hist.d_res_low                        41.04 
_refine_hist.number_atoms_solvent             263 
_refine_hist.number_atoms_total               3592 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3321 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         8 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0032  ? 3420 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7461  ? 4652 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0471  ? 525  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0041  ? 593  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 12.2507 ? 1213 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.85 1.90  . . 138 2482 92.29  . . . . 0.3819 . . . . . . . . . . . 0.4207 
'X-RAY DIFFRACTION' 1.90 1.95  . . 150 2725 99.58  . . . . 0.3263 . . . . . . . . . . . 0.3233 
'X-RAY DIFFRACTION' 1.95 2.00  . . 161 2765 99.86  . . . . 0.2899 . . . . . . . . . . . 0.2983 
'X-RAY DIFFRACTION' 2.00 2.07  . . 132 2669 99.54  . . . . 0.2537 . . . . . . . . . . . 0.2979 
'X-RAY DIFFRACTION' 2.07 2.14  . . 133 2750 99.65  . . . . 0.2492 . . . . . . . . . . . 0.3112 
'X-RAY DIFFRACTION' 2.14 2.23  . . 121 2728 99.69  . . . . 0.2344 . . . . . . . . . . . 0.2774 
'X-RAY DIFFRACTION' 2.23 2.33  . . 133 2754 99.76  . . . . 0.2476 . . . . . . . . . . . 0.2878 
'X-RAY DIFFRACTION' 2.33 2.45  . . 135 2771 100.00 . . . . 0.2135 . . . . . . . . . . . 0.2389 
'X-RAY DIFFRACTION' 2.45 2.61  . . 135 2731 99.97  . . . . 0.2160 . . . . . . . . . . . 0.2677 
'X-RAY DIFFRACTION' 2.61 2.81  . . 132 2755 99.86  . . . . 0.2109 . . . . . . . . . . . 0.2449 
'X-RAY DIFFRACTION' 2.81 3.09  . . 143 2740 99.93  . . . . 0.2097 . . . . . . . . . . . 0.2428 
'X-RAY DIFFRACTION' 3.09 3.54  . . 173 2720 99.93  . . . . 0.1828 . . . . . . . . . . . 0.2491 
'X-RAY DIFFRACTION' 3.54 4.46  . . 136 2785 99.93  . . . . 0.1503 . . . . . . . . . . . 0.2067 
'X-RAY DIFFRACTION' 4.46 41.04 . . 156 2799 99.80  . . . . 0.1598 . . . . . . . . . . . 0.1686 
# 
_struct.entry_id                     8UIH 
_struct.title                        'anti-Phosphohistidine Fab hSC44.ck.20 with 3pTza peptide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UIH 
_struct_keywords.text            
'ANTI-PHOSPHOHISTIDINE ANTIBODY POST-TRANSLATIONAL MODIFICATION ANTIBODY HUMANIZATION, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 5 ? 
G N N 5 ? 
H N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8UIH 8UIH ? 1 ? 1 
2 PDB 8UIH 8UIH ? 2 ? 1 
3 PDB 8UIH 8UIH ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UIH H 1 ? 225 ? 8UIH 1 ? 221 ? 1 221 
2 2 8UIH L 1 ? 218 ? 8UIH 1 ? 212 ? 1 212 
3 3 8UIH D 1 ? 9   ? 8UIH 1 ? 9   ? 1 9   
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 28  ? TYR A 32  ? SER H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2  AA2 SER A 61  ? LYS A 64  ? SER H 61  LYS H 64  5 ? 4 
HELX_P HELX_P3  AA3 ARG A 86  ? THR A 90  ? ARG H 83  THR H 87  5 ? 5 
HELX_P HELX_P4  AA4 SER A 160 ? ALA A 162 ? SER H 156 ALA H 158 5 ? 3 
HELX_P HELX_P5  AA5 SER A 191 ? GLY A 194 ? SER H 187 GLY H 190 5 ? 4 
HELX_P HELX_P6  AA6 LYS A 205 ? ASN A 208 ? LYS H 201 ASN H 204 5 ? 4 
HELX_P HELX_P7  AA7 VAL B 29  B LYS B 33  ? VAL L 27  LYS L 31  5 ? 5 
HELX_P HELX_P8  AA8 GLN B 81  ? PHE B 85  ? GLN L 79  PHE L 83  5 ? 5 
HELX_P HELX_P9  AA9 SER B 127 ? LYS B 132 ? SER L 121 LYS L 126 1 ? 6 
HELX_P HELX_P10 AB1 LYS B 189 ? LYS B 194 ? LYS L 183 LYS L 188 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 22  SG ? ? ? 1_555 A CYS 95  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.023 ? ? 
disulf2 disulf ?    ? A CYS 144 SG A ? ? 1_555 A CYS 200 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.028 ? ? 
disulf3 disulf ?    ? A CYS 144 SG B ? ? 1_555 A CYS 200 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.053 ? ? 
disulf4 disulf ?    ? B CYS 23  SG ? ? ? 1_555 B CYS 90  SG ? ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.050 ? ? 
disulf5 disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG A ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.025 ? ? 
disulf6 disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG B ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.046 ? ? 
covale1 covale both ? C GLY 4   C  ? ? ? 1_555 C UKD 5   N  ? ? D GLY 4   D UKD 5   1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? C UKD 5   C  ? ? ? 1_555 C ALA 6   N  ? ? D UKD 5   D ALA 6   1_555 ? ? ? ? ? ? ? 1.327 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 UKD C 5   ? .   . .   . UKD D 5   ? 1_555 .   . .   . .     .  .  ? 1 UKD None 'Non-standard residue' 
2 CYS A 22  ? CYS A 95  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
3 CYS A 144 A CYS A 200 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
4 CYS A 144 B CYS A 200 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
5 CYS B 23  ? CYS B 90  ? CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG . . .   None 'Disulfide bridge'     
6 CYS B 140 ? CYS B 200 A CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
7 CYS B 140 ? CYS B 200 B CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG . . .   None 'Disulfide bridge'     
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 150 A . ? PHE 146 H PRO 151 A ? PRO 147 H 1 -6.56 
2 GLU 152 A . ? GLU 148 H PRO 153 A ? PRO 149 H 1 -3.28 
3 SER 7   B . ? SER 7   L PRO 8   B ? PRO 8   L 1 -5.44 
4 TYR 146 B . ? TYR 140 L PRO 147 B ? PRO 141 L 1 0.46  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? GLY A 8   ? GLN H 3   GLY H 8   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 THR A 77  ? MET A 82  ? THR H 77  MET H 82  
AA1 4 SER A 67  ? ASN A 72  ? SER H 67  ASN H 72  
AA2 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA2 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA2 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA2 4 PHE A 34  ? GLN A 39  ? PHE H 34  GLN H 39  
AA2 5 LEU A 45  ? LEU A 51  ? LEU H 45  LEU H 51  
AA2 6 ALA A 57  ? TYR A 59  ? ALA H 57  TYR H 59  
AA3 1 LEU A 11  ? VAL A 12  ? LEU H 11  VAL H 12  
AA3 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA3 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA3 4 ILE A 106 ? TRP A 107 ? ILE H 102 TRP H 103 
AA4 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA4 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA4 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA4 4 VAL A 167 ? THR A 169 ? VAL H 163 THR H 165 
AA5 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA5 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA5 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA5 4 VAL A 173 ? LEU A 174 ? VAL H 169 LEU H 170 
AA6 1 THR A 155 ? TRP A 158 ? THR H 151 TRP H 154 
AA6 2 ILE A 199 ? HIS A 204 ? ILE H 195 HIS H 200 
AA6 3 THR A 209 ? LYS A 214 ? THR H 205 LYS H 210 
AA7 1 MET B 4   ? SER B 7   ? MET L 4   SER L 7   
AA7 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA7 3 ASP B 72  ? ILE B 77  ? ASP L 70  ILE L 75  
AA7 4 PHE B 64  ? SER B 69  ? PHE L 62  SER L 67  
AA8 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA8 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA8 3 ALA B 86  ? SER B 96  ? ALA L 84  SER L 94  
AA8 4 VAL B 35  ? GLN B 40  ? VAL L 33  GLN L 38  
AA8 5 LYS B 47  ? TYR B 51  ? LYS L 45  TYR L 49  
AA8 6 SER B 55  ? LEU B 56  ? SER L 53  LEU L 54  
AA9 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA9 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA9 3 ALA B 86  ? SER B 96  ? ALA L 84  SER L 94  
AA9 4 ASP B 99  B PHE B 104 ? ASP L 95  PHE L 98  
AB1 1 SER B 120 ? PHE B 124 ? SER L 114 PHE L 118 
AB1 2 THR B 135 ? PHE B 145 ? THR L 129 PHE L 139 
AB1 3 TYR B 179 ? SER B 188 ? TYR L 173 SER L 182 
AB1 4 SER B 165 ? VAL B 169 ? SER L 159 VAL L 163 
AB2 1 ALA B 159 ? LEU B 160 ? ALA L 153 LEU L 154 
AB2 2 LYS B 151 ? VAL B 156 ? LYS L 145 VAL L 150 
AB2 3 VAL B 197 ? GLN B 204 ? VAL L 191 GLN L 198 
AB2 4 THR B 207 ? ASN B 214 ? THR L 201 ASN L 208 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N LEU A 20  ? N LEU H 20  O LEU A 80  ? O LEU H 80  
AA1 3 4 O THR A 79  ? O THR H 79  N THR A 70  ? N THR H 70  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA2 2 3 O THR A 111 ? O THR H 107 N TYR A 93  ? N TYR H 90  
AA2 3 4 O TYR A 94  ? O TYR H 91  N VAL A 37  ? N VAL H 37  
AA2 4 5 N TRP A 36  ? N TRP H 36  O ILE A 48  ? O ILE H 48  
AA2 5 6 N TYR A 50  ? N TYR H 50  O PHE A 58  ? O PHE H 58  
AA3 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA3 2 3 O THR A 111 ? O THR H 107 N TYR A 93  ? N TYR H 90  
AA3 3 4 N LYS A 97  ? N LYS H 94  O ILE A 106 ? O ILE H 102 
AA4 1 2 N LEU A 128 ? N LEU H 124 O GLY A 143 ? O GLY H 139 
AA4 2 3 N ALA A 140 ? N ALA H 136 O VAL A 188 ? O VAL H 184 
AA4 3 4 O VAL A 185 ? O VAL H 181 N HIS A 168 ? N HIS H 164 
AA5 1 2 N LEU A 128 ? N LEU H 124 O GLY A 143 ? O GLY H 139 
AA5 2 3 N ALA A 140 ? N ALA H 136 O VAL A 188 ? O VAL H 184 
AA5 3 4 O SER A 181 ? O SER H 177 N VAL A 173 ? N VAL H 169 
AA6 1 2 N SER A 157 ? N SER H 153 O ASN A 201 ? O ASN H 197 
AA6 2 3 N VAL A 202 ? N VAL H 198 O VAL A 211 ? O VAL H 207 
AA7 1 2 N THR B 5   ? N THR L 5   O ARG B 24  ? O ARG L 24  
AA7 2 3 N ILE B 21  ? N ILE L 21  O LEU B 75  ? O LEU L 73  
AA7 3 4 O THR B 76  ? O THR L 74  N SER B 65  ? N SER L 63  
AA8 1 2 N ALA B 13  ? N ALA L 13  O LYS B 113 ? O LYS L 107 
AA8 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA8 3 4 O TYR B 89  ? O TYR L 87  N TYR B 38  ? N TYR L 36  
AA8 4 5 N TRP B 37  ? N TRP L 35  O LEU B 49  ? O LEU L 47  
AA8 5 6 N TYR B 51  ? N TYR L 49  O SER B 55  ? O SER L 53  
AA9 1 2 N ALA B 13  ? N ALA L 13  O LYS B 113 ? O LYS L 107 
AA9 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA9 3 4 N TYR B 94  ? N TYR L 92  O TYR B 101 D O TYR L 95  
AB1 1 2 N PHE B 122 ? N PHE L 116 O LEU B 141 ? O LEU L 135 
AB1 2 3 N VAL B 138 ? N VAL L 132 O LEU B 185 ? O LEU L 179 
AB1 3 4 O SER B 182 ? O SER L 176 N SER B 168 ? N SER L 162 
AB2 1 2 O ALA B 159 ? O ALA L 153 N VAL B 156 ? N VAL L 150 
AB2 2 3 N SER B 153 ? N SER L 147 O GLU B 201 ? O GLU L 195 
AB2 3 4 N VAL B 202 ? N VAL L 196 O VAL B 209 ? O VAL L 203 
# 
_pdbx_entry_details.entry_id                   8UIH 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CA 
_pdbx_validate_rmsd_angle.auth_asym_id_1             H 
_pdbx_validate_rmsd_angle.auth_comp_id_1             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_1              140 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             B 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_2             H 
_pdbx_validate_rmsd_angle.auth_comp_id_2             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_2              140 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             B 
_pdbx_validate_rmsd_angle.auth_atom_id_3             SG 
_pdbx_validate_rmsd_angle.auth_asym_id_3             H 
_pdbx_validate_rmsd_angle.auth_comp_id_3             CYS 
_pdbx_validate_rmsd_angle.auth_seq_id_3              140 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             B 
_pdbx_validate_rmsd_angle.angle_value                121.30 
_pdbx_validate_rmsd_angle.angle_target_value         114.20 
_pdbx_validate_rmsd_angle.angle_deviation            7.10 
_pdbx_validate_rmsd_angle.angle_standard_deviation   1.10 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LYS H 43  ? ? -112.62 -169.02 
2 1 LYS L 31  ? ? -133.43 -32.77  
3 1 ILE L 51  ? ? 74.36   -48.23  
4 1 ALA L 84  ? ? 177.18  171.80  
5 1 ASN L 138 ? ? 62.55   69.23   
6 1 PRO L 141 ? ? -77.74  -168.80 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 -x,y,-z         
3 x+1/2,y+1/2,z   
4 -x+1/2,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H SER 215 ? A SER 219 
2  1 Y 1 H CYS 216 ? A CYS 220 
3  1 Y 1 H ASP 217 ? A ASP 221 
4  1 Y 1 H LYS 218 ? A LYS 222 
5  1 Y 1 H THR 219 ? A THR 223 
6  1 Y 1 H HIS 220 ? A HIS 224 
7  1 Y 1 H THR 221 ? A THR 225 
8  1 Y 1 D ALA 1   ? C ALA 1   
9  1 Y 1 D GLY 2   ? C GLY 2   
10 1 Y 1 D GLY 9   ? C GLY 9   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
EDO C1   C N N 88  
EDO O1   O N N 89  
EDO C2   C N N 90  
EDO O2   O N N 91  
EDO H11  H N N 92  
EDO H12  H N N 93  
EDO HO1  H N N 94  
EDO H21  H N N 95  
EDO H22  H N N 96  
EDO HO2  H N N 97  
GLN N    N N N 98  
GLN CA   C N S 99  
GLN C    C N N 100 
GLN O    O N N 101 
GLN CB   C N N 102 
GLN CG   C N N 103 
GLN CD   C N N 104 
GLN OE1  O N N 105 
GLN NE2  N N N 106 
GLN OXT  O N N 107 
GLN H    H N N 108 
GLN H2   H N N 109 
GLN HA   H N N 110 
GLN HB2  H N N 111 
GLN HB3  H N N 112 
GLN HG2  H N N 113 
GLN HG3  H N N 114 
GLN HE21 H N N 115 
GLN HE22 H N N 116 
GLN HXT  H N N 117 
GLU N    N N N 118 
GLU CA   C N S 119 
GLU C    C N N 120 
GLU O    O N N 121 
GLU CB   C N N 122 
GLU CG   C N N 123 
GLU CD   C N N 124 
GLU OE1  O N N 125 
GLU OE2  O N N 126 
GLU OXT  O N N 127 
GLU H    H N N 128 
GLU H2   H N N 129 
GLU HA   H N N 130 
GLU HB2  H N N 131 
GLU HB3  H N N 132 
GLU HG2  H N N 133 
GLU HG3  H N N 134 
GLU HE2  H N N 135 
GLU HXT  H N N 136 
GLY N    N N N 137 
GLY CA   C N N 138 
GLY C    C N N 139 
GLY O    O N N 140 
GLY OXT  O N N 141 
GLY H    H N N 142 
GLY H2   H N N 143 
GLY HA2  H N N 144 
GLY HA3  H N N 145 
GLY HXT  H N N 146 
HIS N    N N N 147 
HIS CA   C N S 148 
HIS C    C N N 149 
HIS O    O N N 150 
HIS CB   C N N 151 
HIS CG   C Y N 152 
HIS ND1  N Y N 153 
HIS CD2  C Y N 154 
HIS CE1  C Y N 155 
HIS NE2  N Y N 156 
HIS OXT  O N N 157 
HIS H    H N N 158 
HIS H2   H N N 159 
HIS HA   H N N 160 
HIS HB2  H N N 161 
HIS HB3  H N N 162 
HIS HD1  H N N 163 
HIS HD2  H N N 164 
HIS HE1  H N N 165 
HIS HE2  H N N 166 
HIS HXT  H N N 167 
HOH O    O N N 168 
HOH H1   H N N 169 
HOH H2   H N N 170 
ILE N    N N N 171 
ILE CA   C N S 172 
ILE C    C N N 173 
ILE O    O N N 174 
ILE CB   C N S 175 
ILE CG1  C N N 176 
ILE CG2  C N N 177 
ILE CD1  C N N 178 
ILE OXT  O N N 179 
ILE H    H N N 180 
ILE H2   H N N 181 
ILE HA   H N N 182 
ILE HB   H N N 183 
ILE HG12 H N N 184 
ILE HG13 H N N 185 
ILE HG21 H N N 186 
ILE HG22 H N N 187 
ILE HG23 H N N 188 
ILE HD11 H N N 189 
ILE HD12 H N N 190 
ILE HD13 H N N 191 
ILE HXT  H N N 192 
LEU N    N N N 193 
LEU CA   C N S 194 
LEU C    C N N 195 
LEU O    O N N 196 
LEU CB   C N N 197 
LEU CG   C N N 198 
LEU CD1  C N N 199 
LEU CD2  C N N 200 
LEU OXT  O N N 201 
LEU H    H N N 202 
LEU H2   H N N 203 
LEU HA   H N N 204 
LEU HB2  H N N 205 
LEU HB3  H N N 206 
LEU HG   H N N 207 
LEU HD11 H N N 208 
LEU HD12 H N N 209 
LEU HD13 H N N 210 
LEU HD21 H N N 211 
LEU HD22 H N N 212 
LEU HD23 H N N 213 
LEU HXT  H N N 214 
LYS N    N N N 215 
LYS CA   C N S 216 
LYS C    C N N 217 
LYS O    O N N 218 
LYS CB   C N N 219 
LYS CG   C N N 220 
LYS CD   C N N 221 
LYS CE   C N N 222 
LYS NZ   N N N 223 
LYS OXT  O N N 224 
LYS H    H N N 225 
LYS H2   H N N 226 
LYS HA   H N N 227 
LYS HB2  H N N 228 
LYS HB3  H N N 229 
LYS HG2  H N N 230 
LYS HG3  H N N 231 
LYS HD2  H N N 232 
LYS HD3  H N N 233 
LYS HE2  H N N 234 
LYS HE3  H N N 235 
LYS HZ1  H N N 236 
LYS HZ2  H N N 237 
LYS HZ3  H N N 238 
LYS HXT  H N N 239 
MET N    N N N 240 
MET CA   C N S 241 
MET C    C N N 242 
MET O    O N N 243 
MET CB   C N N 244 
MET CG   C N N 245 
MET SD   S N N 246 
MET CE   C N N 247 
MET OXT  O N N 248 
MET H    H N N 249 
MET H2   H N N 250 
MET HA   H N N 251 
MET HB2  H N N 252 
MET HB3  H N N 253 
MET HG2  H N N 254 
MET HG3  H N N 255 
MET HE1  H N N 256 
MET HE2  H N N 257 
MET HE3  H N N 258 
MET HXT  H N N 259 
PHE N    N N N 260 
PHE CA   C N S 261 
PHE C    C N N 262 
PHE O    O N N 263 
PHE CB   C N N 264 
PHE CG   C Y N 265 
PHE CD1  C Y N 266 
PHE CD2  C Y N 267 
PHE CE1  C Y N 268 
PHE CE2  C Y N 269 
PHE CZ   C Y N 270 
PHE OXT  O N N 271 
PHE H    H N N 272 
PHE H2   H N N 273 
PHE HA   H N N 274 
PHE HB2  H N N 275 
PHE HB3  H N N 276 
PHE HD1  H N N 277 
PHE HD2  H N N 278 
PHE HE1  H N N 279 
PHE HE2  H N N 280 
PHE HZ   H N N 281 
PHE HXT  H N N 282 
PRO N    N N N 283 
PRO CA   C N S 284 
PRO C    C N N 285 
PRO O    O N N 286 
PRO CB   C N N 287 
PRO CG   C N N 288 
PRO CD   C N N 289 
PRO OXT  O N N 290 
PRO H    H N N 291 
PRO HA   H N N 292 
PRO HB2  H N N 293 
PRO HB3  H N N 294 
PRO HG2  H N N 295 
PRO HG3  H N N 296 
PRO HD2  H N N 297 
PRO HD3  H N N 298 
PRO HXT  H N N 299 
SER N    N N N 300 
SER CA   C N S 301 
SER C    C N N 302 
SER O    O N N 303 
SER CB   C N N 304 
SER OG   O N N 305 
SER OXT  O N N 306 
SER H    H N N 307 
SER H2   H N N 308 
SER HA   H N N 309 
SER HB2  H N N 310 
SER HB3  H N N 311 
SER HG   H N N 312 
SER HXT  H N N 313 
THR N    N N N 314 
THR CA   C N S 315 
THR C    C N N 316 
THR O    O N N 317 
THR CB   C N R 318 
THR OG1  O N N 319 
THR CG2  C N N 320 
THR OXT  O N N 321 
THR H    H N N 322 
THR H2   H N N 323 
THR HA   H N N 324 
THR HB   H N N 325 
THR HG1  H N N 326 
THR HG21 H N N 327 
THR HG22 H N N 328 
THR HG23 H N N 329 
THR HXT  H N N 330 
TRP N    N N N 331 
TRP CA   C N S 332 
TRP C    C N N 333 
TRP O    O N N 334 
TRP CB   C N N 335 
TRP CG   C Y N 336 
TRP CD1  C Y N 337 
TRP CD2  C Y N 338 
TRP NE1  N Y N 339 
TRP CE2  C Y N 340 
TRP CE3  C Y N 341 
TRP CZ2  C Y N 342 
TRP CZ3  C Y N 343 
TRP CH2  C Y N 344 
TRP OXT  O N N 345 
TRP H    H N N 346 
TRP H2   H N N 347 
TRP HA   H N N 348 
TRP HB2  H N N 349 
TRP HB3  H N N 350 
TRP HD1  H N N 351 
TRP HE1  H N N 352 
TRP HE3  H N N 353 
TRP HZ2  H N N 354 
TRP HZ3  H N N 355 
TRP HH2  H N N 356 
TRP HXT  H N N 357 
TYR N    N N N 358 
TYR CA   C N S 359 
TYR C    C N N 360 
TYR O    O N N 361 
TYR CB   C N N 362 
TYR CG   C Y N 363 
TYR CD1  C Y N 364 
TYR CD2  C Y N 365 
TYR CE1  C Y N 366 
TYR CE2  C Y N 367 
TYR CZ   C Y N 368 
TYR OH   O N N 369 
TYR OXT  O N N 370 
TYR H    H N N 371 
TYR H2   H N N 372 
TYR HA   H N N 373 
TYR HB2  H N N 374 
TYR HB3  H N N 375 
TYR HD1  H N N 376 
TYR HD2  H N N 377 
TYR HE1  H N N 378 
TYR HE2  H N N 379 
TYR HH   H N N 380 
TYR HXT  H N N 381 
UKD O3   O N N 382 
UKD O4   O N N 383 
UKD P    P N N 384 
UKD O1   O N N 385 
UKD CE2  C Y N 386 
UKD NE1  N Y N 387 
UKD ND1  N Y N 388 
UKD CD2  C Y N 389 
UKD NG   N Y N 390 
UKD CB   C N N 391 
UKD CA   C N S 392 
UKD N    N N N 393 
UKD C    C N N 394 
UKD O    O N N 395 
UKD H1   H N N 396 
UKD H11  H N N 397 
UKD H3   H N N 398 
UKD H4   H N N 399 
UKD H5   H N N 400 
UKD HA   H N N 401 
UKD H    H N N 402 
UKD H2   H N N 403 
UKD OXT  O N N 404 
UKD HXT  H N N 405 
VAL N    N N N 406 
VAL CA   C N S 407 
VAL C    C N N 408 
VAL O    O N N 409 
VAL CB   C N N 410 
VAL CG1  C N N 411 
VAL CG2  C N N 412 
VAL OXT  O N N 413 
VAL H    H N N 414 
VAL H2   H N N 415 
VAL HA   H N N 416 
VAL HB   H N N 417 
VAL HG11 H N N 418 
VAL HG12 H N N 419 
VAL HG13 H N N 420 
VAL HG21 H N N 421 
VAL HG22 H N N 422 
VAL HG23 H N N 423 
VAL HXT  H N N 424 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
EDO C1  O1   sing N N 83  
EDO C1  C2   sing N N 84  
EDO C1  H11  sing N N 85  
EDO C1  H12  sing N N 86  
EDO O1  HO1  sing N N 87  
EDO C2  O2   sing N N 88  
EDO C2  H21  sing N N 89  
EDO C2  H22  sing N N 90  
EDO O2  HO2  sing N N 91  
GLN N   CA   sing N N 92  
GLN N   H    sing N N 93  
GLN N   H2   sing N N 94  
GLN CA  C    sing N N 95  
GLN CA  CB   sing N N 96  
GLN CA  HA   sing N N 97  
GLN C   O    doub N N 98  
GLN C   OXT  sing N N 99  
GLN CB  CG   sing N N 100 
GLN CB  HB2  sing N N 101 
GLN CB  HB3  sing N N 102 
GLN CG  CD   sing N N 103 
GLN CG  HG2  sing N N 104 
GLN CG  HG3  sing N N 105 
GLN CD  OE1  doub N N 106 
GLN CD  NE2  sing N N 107 
GLN NE2 HE21 sing N N 108 
GLN NE2 HE22 sing N N 109 
GLN OXT HXT  sing N N 110 
GLU N   CA   sing N N 111 
GLU N   H    sing N N 112 
GLU N   H2   sing N N 113 
GLU CA  C    sing N N 114 
GLU CA  CB   sing N N 115 
GLU CA  HA   sing N N 116 
GLU C   O    doub N N 117 
GLU C   OXT  sing N N 118 
GLU CB  CG   sing N N 119 
GLU CB  HB2  sing N N 120 
GLU CB  HB3  sing N N 121 
GLU CG  CD   sing N N 122 
GLU CG  HG2  sing N N 123 
GLU CG  HG3  sing N N 124 
GLU CD  OE1  doub N N 125 
GLU CD  OE2  sing N N 126 
GLU OE2 HE2  sing N N 127 
GLU OXT HXT  sing N N 128 
GLY N   CA   sing N N 129 
GLY N   H    sing N N 130 
GLY N   H2   sing N N 131 
GLY CA  C    sing N N 132 
GLY CA  HA2  sing N N 133 
GLY CA  HA3  sing N N 134 
GLY C   O    doub N N 135 
GLY C   OXT  sing N N 136 
GLY OXT HXT  sing N N 137 
HIS N   CA   sing N N 138 
HIS N   H    sing N N 139 
HIS N   H2   sing N N 140 
HIS CA  C    sing N N 141 
HIS CA  CB   sing N N 142 
HIS CA  HA   sing N N 143 
HIS C   O    doub N N 144 
HIS C   OXT  sing N N 145 
HIS CB  CG   sing N N 146 
HIS CB  HB2  sing N N 147 
HIS CB  HB3  sing N N 148 
HIS CG  ND1  sing Y N 149 
HIS CG  CD2  doub Y N 150 
HIS ND1 CE1  doub Y N 151 
HIS ND1 HD1  sing N N 152 
HIS CD2 NE2  sing Y N 153 
HIS CD2 HD2  sing N N 154 
HIS CE1 NE2  sing Y N 155 
HIS CE1 HE1  sing N N 156 
HIS NE2 HE2  sing N N 157 
HIS OXT HXT  sing N N 158 
HOH O   H1   sing N N 159 
HOH O   H2   sing N N 160 
ILE N   CA   sing N N 161 
ILE N   H    sing N N 162 
ILE N   H2   sing N N 163 
ILE CA  C    sing N N 164 
ILE CA  CB   sing N N 165 
ILE CA  HA   sing N N 166 
ILE C   O    doub N N 167 
ILE C   OXT  sing N N 168 
ILE CB  CG1  sing N N 169 
ILE CB  CG2  sing N N 170 
ILE CB  HB   sing N N 171 
ILE CG1 CD1  sing N N 172 
ILE CG1 HG12 sing N N 173 
ILE CG1 HG13 sing N N 174 
ILE CG2 HG21 sing N N 175 
ILE CG2 HG22 sing N N 176 
ILE CG2 HG23 sing N N 177 
ILE CD1 HD11 sing N N 178 
ILE CD1 HD12 sing N N 179 
ILE CD1 HD13 sing N N 180 
ILE OXT HXT  sing N N 181 
LEU N   CA   sing N N 182 
LEU N   H    sing N N 183 
LEU N   H2   sing N N 184 
LEU CA  C    sing N N 185 
LEU CA  CB   sing N N 186 
LEU CA  HA   sing N N 187 
LEU C   O    doub N N 188 
LEU C   OXT  sing N N 189 
LEU CB  CG   sing N N 190 
LEU CB  HB2  sing N N 191 
LEU CB  HB3  sing N N 192 
LEU CG  CD1  sing N N 193 
LEU CG  CD2  sing N N 194 
LEU CG  HG   sing N N 195 
LEU CD1 HD11 sing N N 196 
LEU CD1 HD12 sing N N 197 
LEU CD1 HD13 sing N N 198 
LEU CD2 HD21 sing N N 199 
LEU CD2 HD22 sing N N 200 
LEU CD2 HD23 sing N N 201 
LEU OXT HXT  sing N N 202 
LYS N   CA   sing N N 203 
LYS N   H    sing N N 204 
LYS N   H2   sing N N 205 
LYS CA  C    sing N N 206 
LYS CA  CB   sing N N 207 
LYS CA  HA   sing N N 208 
LYS C   O    doub N N 209 
LYS C   OXT  sing N N 210 
LYS CB  CG   sing N N 211 
LYS CB  HB2  sing N N 212 
LYS CB  HB3  sing N N 213 
LYS CG  CD   sing N N 214 
LYS CG  HG2  sing N N 215 
LYS CG  HG3  sing N N 216 
LYS CD  CE   sing N N 217 
LYS CD  HD2  sing N N 218 
LYS CD  HD3  sing N N 219 
LYS CE  NZ   sing N N 220 
LYS CE  HE2  sing N N 221 
LYS CE  HE3  sing N N 222 
LYS NZ  HZ1  sing N N 223 
LYS NZ  HZ2  sing N N 224 
LYS NZ  HZ3  sing N N 225 
LYS OXT HXT  sing N N 226 
MET N   CA   sing N N 227 
MET N   H    sing N N 228 
MET N   H2   sing N N 229 
MET CA  C    sing N N 230 
MET CA  CB   sing N N 231 
MET CA  HA   sing N N 232 
MET C   O    doub N N 233 
MET C   OXT  sing N N 234 
MET CB  CG   sing N N 235 
MET CB  HB2  sing N N 236 
MET CB  HB3  sing N N 237 
MET CG  SD   sing N N 238 
MET CG  HG2  sing N N 239 
MET CG  HG3  sing N N 240 
MET SD  CE   sing N N 241 
MET CE  HE1  sing N N 242 
MET CE  HE2  sing N N 243 
MET CE  HE3  sing N N 244 
MET OXT HXT  sing N N 245 
PHE N   CA   sing N N 246 
PHE N   H    sing N N 247 
PHE N   H2   sing N N 248 
PHE CA  C    sing N N 249 
PHE CA  CB   sing N N 250 
PHE CA  HA   sing N N 251 
PHE C   O    doub N N 252 
PHE C   OXT  sing N N 253 
PHE CB  CG   sing N N 254 
PHE CB  HB2  sing N N 255 
PHE CB  HB3  sing N N 256 
PHE CG  CD1  doub Y N 257 
PHE CG  CD2  sing Y N 258 
PHE CD1 CE1  sing Y N 259 
PHE CD1 HD1  sing N N 260 
PHE CD2 CE2  doub Y N 261 
PHE CD2 HD2  sing N N 262 
PHE CE1 CZ   doub Y N 263 
PHE CE1 HE1  sing N N 264 
PHE CE2 CZ   sing Y N 265 
PHE CE2 HE2  sing N N 266 
PHE CZ  HZ   sing N N 267 
PHE OXT HXT  sing N N 268 
PRO N   CA   sing N N 269 
PRO N   CD   sing N N 270 
PRO N   H    sing N N 271 
PRO CA  C    sing N N 272 
PRO CA  CB   sing N N 273 
PRO CA  HA   sing N N 274 
PRO C   O    doub N N 275 
PRO C   OXT  sing N N 276 
PRO CB  CG   sing N N 277 
PRO CB  HB2  sing N N 278 
PRO CB  HB3  sing N N 279 
PRO CG  CD   sing N N 280 
PRO CG  HG2  sing N N 281 
PRO CG  HG3  sing N N 282 
PRO CD  HD2  sing N N 283 
PRO CD  HD3  sing N N 284 
PRO OXT HXT  sing N N 285 
SER N   CA   sing N N 286 
SER N   H    sing N N 287 
SER N   H2   sing N N 288 
SER CA  C    sing N N 289 
SER CA  CB   sing N N 290 
SER CA  HA   sing N N 291 
SER C   O    doub N N 292 
SER C   OXT  sing N N 293 
SER CB  OG   sing N N 294 
SER CB  HB2  sing N N 295 
SER CB  HB3  sing N N 296 
SER OG  HG   sing N N 297 
SER OXT HXT  sing N N 298 
THR N   CA   sing N N 299 
THR N   H    sing N N 300 
THR N   H2   sing N N 301 
THR CA  C    sing N N 302 
THR CA  CB   sing N N 303 
THR CA  HA   sing N N 304 
THR C   O    doub N N 305 
THR C   OXT  sing N N 306 
THR CB  OG1  sing N N 307 
THR CB  CG2  sing N N 308 
THR CB  HB   sing N N 309 
THR OG1 HG1  sing N N 310 
THR CG2 HG21 sing N N 311 
THR CG2 HG22 sing N N 312 
THR CG2 HG23 sing N N 313 
THR OXT HXT  sing N N 314 
TRP N   CA   sing N N 315 
TRP N   H    sing N N 316 
TRP N   H2   sing N N 317 
TRP CA  C    sing N N 318 
TRP CA  CB   sing N N 319 
TRP CA  HA   sing N N 320 
TRP C   O    doub N N 321 
TRP C   OXT  sing N N 322 
TRP CB  CG   sing N N 323 
TRP CB  HB2  sing N N 324 
TRP CB  HB3  sing N N 325 
TRP CG  CD1  doub Y N 326 
TRP CG  CD2  sing Y N 327 
TRP CD1 NE1  sing Y N 328 
TRP CD1 HD1  sing N N 329 
TRP CD2 CE2  doub Y N 330 
TRP CD2 CE3  sing Y N 331 
TRP NE1 CE2  sing Y N 332 
TRP NE1 HE1  sing N N 333 
TRP CE2 CZ2  sing Y N 334 
TRP CE3 CZ3  doub Y N 335 
TRP CE3 HE3  sing N N 336 
TRP CZ2 CH2  doub Y N 337 
TRP CZ2 HZ2  sing N N 338 
TRP CZ3 CH2  sing Y N 339 
TRP CZ3 HZ3  sing N N 340 
TRP CH2 HH2  sing N N 341 
TRP OXT HXT  sing N N 342 
TYR N   CA   sing N N 343 
TYR N   H    sing N N 344 
TYR N   H2   sing N N 345 
TYR CA  C    sing N N 346 
TYR CA  CB   sing N N 347 
TYR CA  HA   sing N N 348 
TYR C   O    doub N N 349 
TYR C   OXT  sing N N 350 
TYR CB  CG   sing N N 351 
TYR CB  HB2  sing N N 352 
TYR CB  HB3  sing N N 353 
TYR CG  CD1  doub Y N 354 
TYR CG  CD2  sing Y N 355 
TYR CD1 CE1  sing Y N 356 
TYR CD1 HD1  sing N N 357 
TYR CD2 CE2  doub Y N 358 
TYR CD2 HD2  sing N N 359 
TYR CE1 CZ   doub Y N 360 
TYR CE1 HE1  sing N N 361 
TYR CE2 CZ   sing Y N 362 
TYR CE2 HE2  sing N N 363 
TYR CZ  OH   sing N N 364 
TYR OH  HH   sing N N 365 
TYR OXT HXT  sing N N 366 
UKD O   C    doub N N 367 
UKD C   CA   sing N N 368 
UKD N   CA   sing N N 369 
UKD CA  CB   sing N N 370 
UKD CB  NG   sing N N 371 
UKD NG  ND1  sing Y N 372 
UKD NG  CD2  sing Y N 373 
UKD ND1 NE1  doub Y N 374 
UKD CD2 CE2  doub Y N 375 
UKD NE1 CE2  sing Y N 376 
UKD CE2 P    sing N N 377 
UKD P   O4   doub N N 378 
UKD P   O3   sing N N 379 
UKD P   O1   sing N N 380 
UKD O3  H1   sing N N 381 
UKD O1  H11  sing N N 382 
UKD CD2 H3   sing N N 383 
UKD CB  H4   sing N N 384 
UKD CB  H5   sing N N 385 
UKD CA  HA   sing N N 386 
UKD N   H    sing N N 387 
UKD N   H2   sing N N 388 
UKD C   OXT  sing N N 389 
UKD OXT HXT  sing N N 390 
VAL N   CA   sing N N 391 
VAL N   H    sing N N 392 
VAL N   H2   sing N N 393 
VAL CA  C    sing N N 394 
VAL CA  CB   sing N N 395 
VAL CA  HA   sing N N 396 
VAL C   O    doub N N 397 
VAL C   OXT  sing N N 398 
VAL CB  CG1  sing N N 399 
VAL CB  CG2  sing N N 400 
VAL CB  HB   sing N N 401 
VAL CG1 HG11 sing N N 402 
VAL CG1 HG12 sing N N 403 
VAL CG1 HG13 sing N N 404 
VAL CG2 HG21 sing N N 405 
VAL CG2 HG22 sing N N 406 
VAL CG2 HG23 sing N N 407 
VAL OXT HXT  sing N N 408 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           CA242443 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6X1V 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'C 1 2 1' 
_space_group.name_Hall        'C 2y' 
_space_group.IT_number        5 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8UIH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.012507 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004862 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013677 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.012182 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . GLU A 1 1   ? 59.61800 -18.42100 35.66000  1.000 65.89869  ? 1   GLU H N    1 
ATOM   2    C CA   . GLU A 1 1   ? 58.40900 -17.82000 36.20800  1.000 67.67832  ? 1   GLU H CA   1 
ATOM   3    C C    . GLU A 1 1   ? 57.18000 -18.60900 35.76800  1.000 62.36797  ? 1   GLU H C    1 
ATOM   4    O O    . GLU A 1 1   ? 57.28700 -19.55900 34.99000  1.000 60.45844  ? 1   GLU H O    1 
ATOM   5    C CB   . GLU A 1 1   ? 58.28100 -16.35500 35.77100  1.000 63.85852  ? 1   GLU H CB   1 
ATOM   6    C CG   . GLU A 1 1   ? 59.60800 -15.61500 35.63800  1.000 65.12847  ? 1   GLU H CG   1 
ATOM   7    C CD   . GLU A 1 1   ? 60.30500 -15.89500 34.31700  1.000 81.51827  ? 1   GLU H CD   1 
ATOM   8    O OE1  . GLU A 1 1   ? 59.61100 -16.25700 33.34300  1.000 75.69829  ? 1   GLU H OE1  1 
ATOM   9    O OE2  . GLU A 1 1   ? 61.54500 -15.76000 34.25400  1.000 90.24819  ? 1   GLU H OE2  1 
ATOM   10   N N    . VAL A 1 2   ? 56.01000 -18.22200 36.28100  1.000 55.87793  ? 2   VAL H N    1 
ATOM   11   C CA   . VAL A 1 2   ? 54.77200 -18.82700 35.81200  1.000 50.42819  ? 2   VAL H CA   1 
ATOM   12   C C    . VAL A 1 2   ? 54.62000 -18.55000 34.32600  1.000 51.79800  ? 2   VAL H C    1 
ATOM   13   O O    . VAL A 1 2   ? 55.00200 -17.48300 33.82700  1.000 46.35813  ? 2   VAL H O    1 
ATOM   14   C CB   . VAL A 1 2   ? 53.56600 -18.29300 36.60200  1.000 46.66887  ? 2   VAL H CB   1 
ATOM   15   C CG1  . VAL A 1 2   ? 53.56800 -18.84600 38.01700  1.000 45.00902  ? 2   VAL H CG1  1 
ATOM   16   C CG2  . VAL A 1 2   ? 53.57900 -16.77400 36.61800  1.000 41.32875  ? 2   VAL H CG2  1 
ATOM   17   N N    . GLN A 1 3   ? 54.06800 -19.52000 33.60600  1.000 46.50832  ? 3   GLN H N    1 
ATOM   18   C CA   . GLN A 1 3   ? 53.82400 -19.34300 32.18700  1.000 42.89771  ? 3   GLN H CA   1 
ATOM   19   C C    . GLN A 1 3   ? 52.57700 -20.12000 31.80600  1.000 42.80852  ? 3   GLN H C    1 
ATOM   20   O O    . GLN A 1 3   ? 52.19000 -21.08500 32.46800  1.000 38.60633  ? 3   GLN H O    1 
ATOM   21   C CB   . GLN A 1 3   ? 55.01200 -19.80300 31.33900  1.000 49.80861  ? 3   GLN H CB   1 
ATOM   22   C CG   . GLN A 1 3   ? 55.35600 -18.83900 30.21600  1.000 54.30863  ? 3   GLN H CG   1 
ATOM   23   C CD   . GLN A 1 3   ? 56.04400 -19.52000 29.05400  1.000 54.98854  ? 3   GLN H CD   1 
ATOM   24   O OE1  . GLN A 1 3   ? 56.76400 -20.50300 29.23400  1.000 54.45853  ? 3   GLN H OE1  1 
ATOM   25   N NE2  . GLN A 1 3   ? 55.81500 -19.01000 27.84800  1.000 52.33872  ? 3   GLN H NE2  1 
ATOM   26   H HA   . GLN A 1 3   ? 53.67400 -18.40200 32.00600  1.000 51.48082  ? 3   GLN H HA   1 
ATOM   27   H HB2  . GLN A 1 3   ? 55.79200 -19.88600 31.91000  1.000 59.77390  ? 3   GLN H HB2  1 
ATOM   28   H HB3  . GLN A 1 3   ? 54.80000 -20.66200 30.94100  1.000 59.77390  ? 3   GLN H HB3  1 
ATOM   29   H HG2  . GLN A 1 3   ? 54.53800 -18.43400 29.88600  1.000 65.17393  ? 3   GLN H HG2  1 
ATOM   30   H HG3  . GLN A 1 3   ? 55.95000 -18.15400 30.55900  1.000 65.17393  ? 3   GLN H HG3  1 
ATOM   31   H HE21 . GLN A 1 3   ? 55.29800 -18.32800 27.76100  1.000 62.81003  ? 3   GLN H HE21 1 
ATOM   32   H HE22 . GLN A 1 3   ? 56.18300 -19.36100 27.15500  1.000 62.81003  ? 3   GLN H HE22 1 
ATOM   33   N N    . LEU A 1 4   ? 51.96200 -19.69300 30.71300  1.000 40.18743  ? 4   LEU H N    1 
ATOM   34   C CA   . LEU A 1 4   ? 50.71300 -20.28200 30.23800  1.000 37.22682  ? 4   LEU H CA   1 
ATOM   35   C C    . LEU A 1 4   ? 50.83600 -20.36100 28.72100  1.000 37.08818  ? 4   LEU H C    1 
ATOM   36   O O    . LEU A 1 4   ? 50.63900 -19.36200 28.02500  1.000 34.07712  ? 4   LEU H O    1 
ATOM   37   C CB   . LEU A 1 4   ? 49.53000 -19.44100 30.69000  1.000 37.58898  ? 4   LEU H CB   1 
ATOM   38   C CG   . LEU A 1 4   ? 48.11600 -19.99000 30.53400  1.000 41.59876  ? 4   LEU H CG   1 
ATOM   39   C CD1  . LEU A 1 4   ? 47.96300 -21.32000 31.24800  1.000 38.75839  ? 4   LEU H CD1  1 
ATOM   40   C CD2  . LEU A 1 4   ? 47.11100 -18.96500 31.06700  1.000 31.98791  ? 4   LEU H CD2  1 
ATOM   41   H H    . LEU A 1 4   ? 52.25100 -19.05200 30.21800  1.000 48.22849  ? 4   LEU H H    1 
ATOM   42   H HA   . LEU A 1 4   ? 50.58500 -21.18000 30.58100  1.000 44.67575  ? 4   LEU H HA   1 
ATOM   43   H HB2  . LEU A 1 4   ? 49.64900 -19.26000 31.63600  1.000 45.11035  ? 4   LEU H HB2  1 
ATOM   44   H HB3  . LEU A 1 4   ? 49.55700 -18.61100 30.18800  1.000 45.11035  ? 4   LEU H HB3  1 
ATOM   45   H HG   . LEU A 1 4   ? 47.93300 -20.14900 29.59500  1.000 49.92209  ? 4   LEU H HG   1 
ATOM   46   H HD11 . LEU A 1 4   ? 47.04400 -21.41700 31.54200  1.000 46.51364  ? 4   LEU H HD11 1 
ATOM   47   H HD12 . LEU A 1 4   ? 48.19200 -22.03600 30.63500  1.000 46.51364  ? 4   LEU H HD12 1 
ATOM   48   H HD13 . LEU A 1 4   ? 48.55800 -21.33800 32.01400  1.000 46.51364  ? 4   LEU H HD13 1 
ATOM   49   H HD21 . LEU A 1 4   ? 46.35400 -18.92100 30.46200  1.000 38.38907  ? 4   LEU H HD21 1 
ATOM   50   H HD22 . LEU A 1 4   ? 46.81500 -19.24200 31.94800  1.000 38.38907  ? 4   LEU H HD22 1 
ATOM   51   H HD23 . LEU A 1 4   ? 47.54300 -18.09800 31.12000  1.000 38.38907  ? 4   LEU H HD23 1 
ATOM   52   N N    . VAL A 1 5   ? 51.19400 -21.53800 28.21500  1.000 35.88748  ? 5   VAL H N    1 
ATOM   53   C CA   . VAL A 1 5   ? 51.57200 -21.71200 26.81700  1.000 34.69805  ? 5   VAL H CA   1 
ATOM   54   C C    . VAL A 1 5   ? 50.38500 -22.26900 26.04500  1.000 32.89833  ? 5   VAL H C    1 
ATOM   55   O O    . VAL A 1 5   ? 49.86400 -23.34200 26.37400  1.000 33.31853  ? 5   VAL H O    1 
ATOM   56   C CB   . VAL A 1 5   ? 52.79700 -22.62900 26.68200  1.000 35.79873  ? 5   VAL H CB   1 
ATOM   57   C CG1  . VAL A 1 5   ? 53.04800 -22.95600 25.22300  1.000 32.93904  ? 5   VAL H CG1  1 
ATOM   58   C CG2  . VAL A 1 5   ? 54.01500 -21.97200 27.31500  1.000 40.18868  ? 5   VAL H CG2  1 
ATOM   59   H H    . VAL A 1 5   ? 51.22500 -22.26500 28.67200  1.000 43.06854  ? 5   VAL H H    1 
ATOM   60   H HA   . VAL A 1 5   ? 51.78600 -20.84300 26.44200  1.000 41.64123  ? 5   VAL H HA   1 
ATOM   61   H HB   . VAL A 1 5   ? 52.63000 -23.46300 27.14900  1.000 42.96204  ? 5   VAL H HB   1 
ATOM   62   H HG11 . VAL A 1 5   ? 53.98800 -23.16100 25.10300  1.000 39.53042  ? 5   VAL H HG11 1 
ATOM   63   H HG12 . VAL A 1 5   ? 52.50700 -23.72200 24.97400  1.000 39.53042  ? 5   VAL H HG12 1 
ATOM   64   H HG13 . VAL A 1 5   ? 52.80400 -22.18900 24.68100  1.000 39.53042  ? 5   VAL H HG13 1 
ATOM   65   H HG21 . VAL A 1 5   ? 54.78300 -22.55400 27.20100  1.000 48.22998  ? 5   VAL H HG21 1 
ATOM   66   H HG22 . VAL A 1 5   ? 54.17800 -21.12100 26.87800  1.000 48.22998  ? 5   VAL H HG22 1 
ATOM   67   H HG23 . VAL A 1 5   ? 53.84400 -21.83100 28.25900  1.000 48.22998  ? 5   VAL H HG23 1 
ATOM   68   N N    . GLU A 1 6   ? 49.97900 -21.55300 25.00300  1.000 30.68775  ? 6   GLU H N    1 
ATOM   69   C CA   . GLU A 1 6   ? 48.80900 -21.88900 24.20900  1.000 31.00831  ? 6   GLU H CA   1 
ATOM   70   C C    . GLU A 1 6   ? 49.22200 -22.67700 22.97300  1.000 27.56708  ? 6   GLU H C    1 
ATOM   71   O O    . GLU A 1 6   ? 50.31300 -22.49000 22.43200  1.000 29.99872  ? 6   GLU H O    1 
ATOM   72   C CB   . GLU A 1 6   ? 48.06800 -20.61600 23.80100  1.000 29.21775  ? 6   GLU H CB   1 
ATOM   73   C CG   . GLU A 1 6   ? 46.67400 -20.82900 23.26700  1.000 29.40835  ? 6   GLU H CG   1 
ATOM   74   C CD   . GLU A 1 6   ? 45.93000 -19.51900 23.12000  1.000 24.90695  ? 6   GLU H CD   1 
ATOM   75   O OE1  . GLU A 1 6   ? 46.48800 -18.47400 23.51900  1.000 25.70762  ? 6   GLU H OE1  1 
ATOM   76   O OE2  . GLU A 1 6   ? 44.78900 -19.53600 22.61500  1.000 24.76813  ? 6   GLU H OE2  1 
ATOM   77   H H    . GLU A 1 6   ? 50.38000 -20.84300 24.72800  1.000 36.82887  ? 6   GLU H H    1 
ATOM   78   H HA   . GLU A 1 6   ? 48.20300 -22.44400 24.72500  1.000 37.21354  ? 6   GLU H HA   1 
ATOM   79   H HB2  . GLU A 1 6   ? 47.99600 -20.04100 24.58000  1.000 35.06487  ? 6   GLU H HB2  1 
ATOM   80   H HB3  . GLU A 1 6   ? 48.58000 -20.17200 23.10800  1.000 35.06487  ? 6   GLU H HB3  1 
ATOM   81   H HG2  . GLU A 1 6   ? 46.72600 -21.25000 22.39500  1.000 35.29360  ? 6   GLU H HG2  1 
ATOM   82   H HG3  . GLU A 1 6   ? 46.17800 -21.39500 23.88000  1.000 35.29360  ? 6   GLU H HG3  1 
ATOM   83   N N    . SER A 1 7   ? 48.34000 -23.57200 22.53800  1.000 27.33677  ? 7   SER H N    1 
ATOM   84   C CA   . SER A 1 7   ? 48.60500 -24.38000 21.35900  1.000 31.65904  ? 7   SER H CA   1 
ATOM   85   C C    . SER A 1 7   ? 47.28200 -24.80200 20.74100  1.000 33.30909  ? 7   SER H C    1 
ATOM   86   O O    . SER A 1 7   ? 46.22300 -24.71100 21.36600  1.000 30.17821  ? 7   SER H O    1 
ATOM   87   C CB   . SER A 1 7   ? 49.45000 -25.61200 21.70000  1.000 33.68927  ? 7   SER H CB   1 
ATOM   88   O OG   . SER A 1 7   ? 48.81200 -26.39900 22.68900  1.000 32.97743  ? 7   SER H OG   1 
ATOM   89   H H    . SER A 1 7   ? 47.58100 -23.72700 22.91000  1.000 32.80770  ? 7   SER H H    1 
ATOM   90   H HA   . SER A 1 7   ? 49.08900 -23.84900 20.70800  1.000 37.99442  ? 7   SER H HA   1 
ATOM   91   H HB2  . SER A 1 7   ? 49.56900 -26.14600 20.89900  1.000 40.43069  ? 7   SER H HB2  1 
ATOM   92   H HB3  . SER A 1 7   ? 50.31300 -25.32100 22.03500  1.000 40.43069  ? 7   SER H HB3  1 
ATOM   93   H HG   . SER A 1 7   ? 47.98100 -26.39300 22.56900  1.000 39.57649  ? 7   SER H HG   1 
ATOM   94   N N    . GLY A 1 8   ? 47.35700 -25.27000 19.50000  1.000 29.54680  ? 8   GLY H N    1 
ATOM   95   C CA   . GLY A 1 8   ? 46.16500 -25.69000 18.79500  1.000 32.69755  ? 8   GLY H CA   1 
ATOM   96   C C    . GLY A 1 8   ? 46.10200 -25.14300 17.38700  1.000 36.79843  ? 8   GLY H C    1 
ATOM   97   O O    . GLY A 1 8   ? 46.69700 -24.10200 17.08800  1.000 31.16668  ? 8   GLY H O    1 
ATOM   98   H H    . GLY A 1 8   ? 48.08600 -25.35300 19.05100  1.000 35.45973  ? 8   GLY H H    1 
ATOM   99   H HA2  . GLY A 1 8   ? 46.14500 -26.65800 18.74800  1.000 39.24063  ? 8   GLY H HA2  1 
ATOM   100  H HA3  . GLY A 1 8   ? 45.38200 -25.38100 19.27800  1.000 39.24063  ? 8   GLY H HA3  1 
ATOM   101  N N    . GLY A 1 9   ? 45.36000 -25.83000 16.52000  1.000 40.33827  ? 9   GLY H N    1 
ATOM   102  C CA   . GLY A 1 9   ? 45.39000 -25.50400 15.10700  1.000 38.08759  ? 9   GLY H CA   1 
ATOM   103  C C    . GLY A 1 9   ? 44.91600 -24.09100 14.82400  1.000 31.88684  ? 9   GLY H C    1 
ATOM   104  O O    . GLY A 1 9   ? 44.02700 -23.55700 15.48800  1.000 31.14799  ? 9   GLY H O    1 
ATOM   105  H H    . GLY A 1 9   ? 44.83800 -26.48100 16.72600  1.000 48.40950  ? 9   GLY H H    1 
ATOM   106  H HA2  . GLY A 1 9   ? 46.29800 -25.59300 14.77700  1.000 45.70868  ? 9   GLY H HA2  1 
ATOM   107  H HA3  . GLY A 1 9   ? 44.81700 -26.12000 14.62400  1.000 45.70868  ? 9   GLY H HA3  1 
ATOM   108  N N    . GLY A 1 10  ? 45.52000 -23.48900 13.80200  1.000 35.50007  ? 10  GLY H N    1 
ATOM   109  C CA   . GLY A 1 10  ? 45.16600 -22.14700 13.38900  1.000 28.22911  ? 10  GLY H CA   1 
ATOM   110  C C    . GLY A 1 10  ? 44.14000 -22.10300 12.27500  1.000 25.38864  ? 10  GLY H C    1 
ATOM   111  O O    . GLY A 1 10  ? 43.27700 -21.22200 12.26400  1.000 27.40124  ? 10  GLY H O    1 
ATOM   112  H H    . GLY A 1 10  ? 46.14400 -23.84600 13.33000  1.000 42.60365  ? 10  GLY H H    1 
ATOM   113  H HA2  . GLY A 1 10  ? 44.80400 -21.66800 14.15000  1.000 33.87850  ? 10  GLY H HA2  1 
ATOM   114  H HA3  . GLY A 1 10  ? 45.96500 -21.69200 13.08000  1.000 33.87850  ? 10  GLY H HA3  1 
ATOM   115  N N    . LEU A 1 11  ? 44.22300 -23.03500 11.32800  1.000 25.44848  ? 11  LEU H N    1 
ATOM   116  C CA   . LEU A 1 11  ? 43.32500 -23.07500 10.17800  1.000 22.80793  ? 11  LEU H CA   1 
ATOM   117  C C    . LEU A 1 11  ? 42.27600 -24.16300 10.38400  1.000 22.79807  ? 11  LEU H C    1 
ATOM   118  O O    . LEU A 1 11  ? 42.62300 -25.33100 10.58700  1.000 21.45620  ? 11  LEU H O    1 
ATOM   119  C CB   . LEU A 1 11  ? 44.11000 -23.32900 8.89200   1.000 21.99771  ? 11  LEU H CB   1 
ATOM   120  C CG   . LEU A 1 11  ? 43.27100 -23.40400 7.61700   1.000 20.82801  ? 11  LEU H CG   1 
ATOM   121  C CD1  . LEU A 1 11  ? 42.44100 -22.13900 7.44800   1.000 20.43857  ? 11  LEU H CD1  1 
ATOM   122  C CD2  . LEU A 1 11  ? 44.16200 -23.63400 6.40100   1.000 21.50862  ? 11  LEU H CD2  1 
ATOM   123  H H    . LEU A 1 11  ? 44.80500 -23.66900 11.33100  1.000 30.54174  ? 11  LEU H H    1 
ATOM   124  H HA   . LEU A 1 11  ? 42.86600 -22.22400 10.10400  1.000 27.37308  ? 11  LEU H HA   1 
ATOM   125  H HB2  . LEU A 1 11  ? 44.74800 -22.60800 8.77600   1.000 26.40082  ? 11  LEU H HB2  1 
ATOM   126  H HB3  . LEU A 1 11  ? 44.57800 -24.17500 8.98100   1.000 26.40082  ? 11  LEU H HB3  1 
ATOM   127  H HG   . LEU A 1 11  ? 42.65900 -24.15500 7.68400   1.000 24.99719  ? 11  LEU H HG   1 
ATOM   128  H HD11 . LEU A 1 11  ? 42.00000 -22.16300 6.58500   1.000 24.52986  ? 11  LEU H HD11 1 
ATOM   129  H HD12 . LEU A 1 11  ? 41.77900 -22.09800 8.15700   1.000 24.52986  ? 11  LEU H HD12 1 
ATOM   130  H HD13 . LEU A 1 11  ? 43.02700 -21.36800 7.49900   1.000 24.52986  ? 11  LEU H HD13 1 
ATOM   131  H HD21 . LEU A 1 11  ? 43.60400 -23.72000 5.61200   1.000 25.81392  ? 11  LEU H HD21 1 
ATOM   132  H HD22 . LEU A 1 11  ? 44.76200 -22.87800 6.30200   1.000 25.81392  ? 11  LEU H HD22 1 
ATOM   133  H HD23 . LEU A 1 11  ? 44.67300 -24.44800 6.53400   1.000 25.81392  ? 11  LEU H HD23 1 
ATOM   134  N N    . VAL A 1 12  ? 41.00000 -23.78200 10.31500  1.000 21.24698  ? 12  VAL H N    1 
ATOM   135  C CA   . VAL A 1 12  ? 39.87900 -24.69500 10.50800  1.000 23.13805  ? 12  VAL H CA   1 
ATOM   136  C C    . VAL A 1 12  ? 38.85800 -24.44100 9.40700   1.000 23.30914  ? 12  VAL H C    1 
ATOM   137  O O    . VAL A 1 12  ? 38.65100 -23.29500 8.99700   1.000 19.61547  ? 12  VAL H O    1 
ATOM   138  C CB   . VAL A 1 12  ? 39.23200 -24.51700 11.89800  1.000 25.24915  ? 12  VAL H CB   1 
ATOM   139  C CG1  . VAL A 1 12  ? 37.99700 -25.39600 12.02900  1.000 30.83133  ? 12  VAL H CG1  1 
ATOM   140  C CG2  . VAL A 1 12  ? 40.23500 -24.83500 12.99100  1.000 24.08797  ? 12  VAL H CG2  1 
ATOM   141  H H    . VAL A 1 12  ? 40.75400 -22.97400 10.15300  1.000 25.49995  ? 12  VAL H H    1 
ATOM   142  H HA   . VAL A 1 12  ? 40.19200 -25.61000 10.43300  1.000 27.76923  ? 12  VAL H HA   1 
ATOM   143  H HB   . VAL A 1 12  ? 38.95500 -23.59300 12.00000  1.000 30.30255  ? 12  VAL H HB   1 
ATOM   144  H HG11 . VAL A 1 12  ? 37.76600 -25.47800 12.96800  1.000 37.00117  ? 12  VAL H HG11 1 
ATOM   145  H HG12 . VAL A 1 12  ? 37.26400 -24.98600 11.54300  1.000 37.00117  ? 12  VAL H HG12 1 
ATOM   146  H HG13 . VAL A 1 12  ? 38.19100 -26.27100 11.65800  1.000 37.00117  ? 12  VAL H HG13 1 
ATOM   147  H HG21 . VAL A 1 12  ? 39.81000 -24.71500 13.85500  1.000 28.90914  ? 12  VAL H HG21 1 
ATOM   148  H HG22 . VAL A 1 12  ? 40.52900 -25.75400 12.89200  1.000 28.90914  ? 12  VAL H HG22 1 
ATOM   149  H HG23 . VAL A 1 12  ? 40.99300 -24.23500 12.91000  1.000 28.90914  ? 12  VAL H HG23 1 
ATOM   150  N N    . GLN A 1 13  ? 38.20100 -25.52900 8.92400   1.000 22.11705  ? 13  GLN H N    1 
ATOM   151  C CA   . GLN A 1 13  ? 37.28000 -25.33200 7.81000   1.000 24.24783  ? 13  GLN H CA   1 
ATOM   152  C C    . GLN A 1 13  ? 35.88800 -24.94300 8.30200   1.000 22.97671  ? 13  GLN H C    1 
ATOM   153  O O    . GLN A 1 13  ? 35.46300 -25.36600 9.38100   1.000 21.65480  ? 13  GLN H O    1 
ATOM   154  C CB   . GLN A 1 13  ? 37.18000 -26.60600 6.97000   1.000 31.82970  ? 13  GLN H CB   1 
ATOM   155  C CG   . GLN A 1 13  ? 38.48900 -27.02100 6.31000   1.000 30.93753  ? 13  GLN H CG   1 
ATOM   156  C CD   . GLN A 1 13  ? 38.33700 -27.35200 4.83200   1.000 35.81938  ? 13  GLN H CD   1 
ATOM   157  O OE1  . GLN A 1 13  ? 37.22600 -27.54200 4.32800   1.000 37.11986  ? 13  GLN H OE1  1 
ATOM   158  N NE2  . GLN A 1 13  ? 39.46000 -27.41900 4.13000   1.000 34.55933  ? 13  GLN H NE2  1 
ATOM   159  H H    . GLN A 1 13  ? 38.27700 -26.33400 9.21500   1.000 26.54403  ? 13  GLN H H    1 
ATOM   160  H HA   . GLN A 1 13  ? 37.61100 -24.61400 7.24800   1.000 29.10097  ? 13  GLN H HA   1 
ATOM   161  H HB2  . GLN A 1 13  ? 36.89600 -27.33500 7.54400   1.000 38.19921  ? 13  GLN H HB2  1 
ATOM   162  H HB3  . GLN A 1 13  ? 36.52700 -26.46400 6.26700   1.000 38.19921  ? 13  GLN H HB3  1 
ATOM   163  H HG2  . GLN A 1 13  ? 39.12500 -26.29200 6.38800   1.000 37.12861  ? 13  GLN H HG2  1 
ATOM   164  H HG3  . GLN A 1 13  ? 38.83200 -27.81000 6.75800   1.000 37.12861  ? 13  GLN H HG3  1 
ATOM   165  H HE21 . GLN A 1 13  ? 40.21700 -27.27900 4.51400   1.000 41.47476  ? 13  GLN H HE21 1 
ATOM   166  H HE22 . GLN A 1 13  ? 39.43200 -27.60200 3.29000   1.000 41.47476  ? 13  GLN H HE22 1 
ATOM   167  N N    . PRO A 1 14  ? 35.14900 -24.14600 7.52700   1.000 21.54639  ? 14  PRO H N    1 
ATOM   168  C CA   . PRO A 1 14  ? 33.75600 -23.86000 7.89100   1.000 23.33654  ? 14  PRO H CA   1 
ATOM   169  C C    . PRO A 1 14  ? 32.99900 -25.15200 8.15500   1.000 26.51671  ? 14  PRO H C    1 
ATOM   170  O O    . PRO A 1 14  ? 33.18800 -26.15600 7.46500   1.000 28.80786  ? 14  PRO H O    1 
ATOM   171  C CB   . PRO A 1 14  ? 33.20600 -23.12700 6.66200   1.000 27.62934  ? 14  PRO H CB   1 
ATOM   172  C CG   . PRO A 1 14  ? 34.40300 -22.60300 5.94900   1.000 25.60959  ? 14  PRO H CG   1 
ATOM   173  C CD   . PRO A 1 14  ? 35.50400 -23.58200 6.21100   1.000 24.08852  ? 14  PRO H CD   1 
ATOM   174  H HA   . PRO A 1 14  ? 33.70900 -23.27700 8.66400   1.000 28.00742  ? 14  PRO H HA   1 
ATOM   175  H HB2  . PRO A 1 14  ? 32.71300 -23.74700 6.10200   1.000 33.15878  ? 14  PRO H HB2  1 
ATOM   176  H HB3  . PRO A 1 14  ? 32.62700 -22.40100 6.94400   1.000 33.15878  ? 14  PRO H HB3  1 
ATOM   177  H HG2  . PRO A 1 14  ? 34.21600 -22.54400 4.99900   1.000 30.73507  ? 14  PRO H HG2  1 
ATOM   178  H HG3  . PRO A 1 14  ? 34.63300 -21.72700 6.29600   1.000 30.73507  ? 14  PRO H HG3  1 
ATOM   179  H HD2  . PRO A 1 14  ? 35.52100 -24.27400 5.53200   1.000 28.90980  ? 14  PRO H HD2  1 
ATOM   180  H HD3  . PRO A 1 14  ? 36.36400 -23.13300 6.24800   1.000 28.90980  ? 14  PRO H HD3  1 
ATOM   181  N N    . GLY A 1 15  ? 32.13000 -25.12000 9.16400   1.000 28.84809  ? 15  GLY H N    1 
ATOM   182  C CA   . GLY A 1 15  ? 31.41000 -26.29700 9.59500   1.000 31.43879  ? 15  GLY H CA   1 
ATOM   183  C C    . GLY A 1 15  ? 32.19400 -27.24100 10.47800  1.000 30.20833  ? 15  GLY H C    1 
ATOM   184  O O    . GLY A 1 15  ? 31.60500 -28.18200 11.02700  1.000 31.54846  ? 15  GLY H O    1 
ATOM   185  H H    . GLY A 1 15  ? 31.94300 -24.41400 9.61700   1.000 34.62128  ? 15  GLY H H    1 
ATOM   186  H HA2  . GLY A 1 15  ? 30.62400 -26.01600 10.08900  1.000 37.73012  ? 15  GLY H HA2  1 
ATOM   187  H HA3  . GLY A 1 15  ? 31.12900 -26.79300 8.81000   1.000 37.73012  ? 15  GLY H HA3  1 
ATOM   188  N N    . GLY A 1 16  ? 33.49600 -27.03200 10.63200  1.000 27.43716  ? 16  GLY H N    1 
ATOM   189  C CA   . GLY A 1 16  ? 34.32500 -27.86800 11.47100  1.000 26.65679  ? 16  GLY H CA   1 
ATOM   190  C C    . GLY A 1 16  ? 34.43300 -27.33600 12.88300  1.000 30.63944  ? 16  GLY H C    1 
ATOM   191  O O    . GLY A 1 16  ? 33.65700 -26.48200 13.31900  1.000 29.96784  ? 16  GLY H O    1 
ATOM   192  H H    . GLY A 1 16  ? 33.92800 -26.39500 10.24800  1.000 32.92817  ? 16  GLY H H    1 
ATOM   193  H HA2  . GLY A 1 16  ? 33.94800 -28.76100 11.50800  1.000 31.99172  ? 16  GLY H HA2  1 
ATOM   194  H HA3  . GLY A 1 16  ? 35.21800 -27.91800 11.09400  1.000 31.99172  ? 16  GLY H HA3  1 
ATOM   195  N N    . SER A 1 17  ? 35.42800 -27.85100 13.60300  1.000 28.72770  ? 17  SER H N    1 
ATOM   196  C CA   . SER A 1 17  ? 35.62700 -27.54200 15.00900  1.000 28.53760  ? 17  SER H CA   1 
ATOM   197  C C    . SER A 1 17  ? 37.04300 -27.03700 15.23900  1.000 29.41923  ? 17  SER H C    1 
ATOM   198  O O    . SER A 1 17  ? 37.98400 -27.44500 14.55500  1.000 27.60786  ? 17  SER H O    1 
ATOM   199  C CB   . SER A 1 17  ? 35.38600 -28.77800 15.89600  1.000 31.64870  ? 17  SER H CB   1 
ATOM   200  O OG   . SER A 1 17  ? 34.01900 -29.14600 15.91700  1.000 38.17893  ? 17  SER H OG   1 
ATOM   201  H H    . SER A 1 17  ? 36.01500 -28.39500 13.28700  1.000 34.47681  ? 17  SER H H    1 
ATOM   202  H HA   . SER A 1 17  ? 35.00700 -26.84300 15.26800  1.000 34.24870  ? 17  SER H HA   1 
ATOM   203  H HB2  . SER A 1 17  ? 35.90400 -29.52000 15.54600  1.000 37.98202  ? 17  SER H HB2  1 
ATOM   204  H HB3  . SER A 1 17  ? 35.66900 -28.57400 16.80100  1.000 37.98202  ? 17  SER H HB3  1 
ATOM   205  H HG   . SER A 1 17  ? 33.74100 -29.26500 15.13300  1.000 45.81828  ? 17  SER H HG   1 
ATOM   206  N N    . LEU A 1 18  ? 37.18500 -26.14300 16.21000  1.000 25.55610  ? 18  LEU H N    1 
ATOM   207  C CA   . LEU A 1 18  ? 38.49300 -25.74700 16.70700  1.000 25.88658  ? 18  LEU H CA   1 
ATOM   208  C C    . LEU A 1 18  ? 38.74800 -26.44200 18.03800  1.000 28.47806  ? 18  LEU H C    1 
ATOM   209  O O    . LEU A 1 18  ? 37.81500 -26.78100 18.77200  1.000 26.62642  ? 18  LEU H O    1 
ATOM   210  C CB   . LEU A 1 18  ? 38.59700 -24.23000 16.87300  1.000 26.27801  ? 18  LEU H CB   1 
ATOM   211  C CG   . LEU A 1 18  ? 37.80100 -23.55900 17.99200  1.000 27.84784  ? 18  LEU H CG   1 
ATOM   212  C CD1  . LEU A 1 18  ? 38.53600 -23.60700 19.32200  1.000 29.01858  ? 18  LEU H CD1  1 
ATOM   213  C CD2  . LEU A 1 18  ? 37.48900 -22.11500 17.62200  1.000 29.55902  ? 18  LEU H CD2  1 
ATOM   214  H H    . LEU A 1 18  ? 36.52900 -25.74800 16.60100  1.000 30.67089  ? 18  LEU H H    1 
ATOM   215  H HA   . LEU A 1 18  ? 39.18000 -26.00900 16.07400  1.000 31.06747  ? 18  LEU H HA   1 
ATOM   216  H HB2  . LEU A 1 18  ? 39.53000 -24.01700 17.03300  1.000 31.53719  ? 18  LEU H HB2  1 
ATOM   217  H HB3  . LEU A 1 18  ? 38.30200 -23.82400 16.04300  1.000 31.53719  ? 18  LEU H HB3  1 
ATOM   218  H HG   . LEU A 1 18  ? 36.97100 -24.04700 18.10300  1.000 33.42098  ? 18  LEU H HG   1 
ATOM   219  H HD11 . LEU A 1 18  ? 38.11200 -22.99100 19.93900  1.000 34.82586  ? 18  LEU H HD11 1 
ATOM   220  H HD12 . LEU A 1 18  ? 38.49300 -24.51000 19.67300  1.000 34.82586  ? 18  LEU H HD12 1 
ATOM   221  H HD13 . LEU A 1 18  ? 39.46100 -23.35000 19.18100  1.000 34.82586  ? 18  LEU H HD13 1 
ATOM   222  H HD21 . LEU A 1 18  ? 37.00000 -21.70100 18.35000  1.000 35.47440  ? 18  LEU H HD21 1 
ATOM   223  H HD22 . LEU A 1 18  ? 38.32200 -21.64000 17.47100  1.000 35.47440  ? 18  LEU H HD22 1 
ATOM   224  H HD23 . LEU A 1 18  ? 36.95200 -22.10500 16.81400  1.000 35.47440  ? 18  LEU H HD23 1 
ATOM   225  N N    . ARG A 1 19  ? 40.02500 -26.65200 18.34300  1.000 26.36628  ? 19  ARG H N    1 
ATOM   226  C CA   . ARG A 1 19  ? 40.43800 -27.26300 19.60300  1.000 28.90698  ? 19  ARG H CA   1 
ATOM   227  C C    . ARG A 1 19  ? 41.73200 -26.58900 20.03400  1.000 29.48757  ? 19  ARG H C    1 
ATOM   228  O O    . ARG A 1 19  ? 42.76800 -26.76600 19.38700  1.000 27.75631  ? 19  ARG H O    1 
ATOM   229  C CB   . ARG A 1 19  ? 40.62200 -28.77200 19.45100  1.000 36.95812  ? 19  ARG H CB   1 
ATOM   230  C CG   . ARG A 1 19  ? 41.09300 -29.48200 20.70800  1.000 43.33838  ? 19  ARG H CG   1 
ATOM   231  C CD   . ARG A 1 19  ? 41.16300 -30.98600 20.47900  1.000 62.12795  ? 19  ARG H CD   1 
ATOM   232  N NE   . ARG A 1 19  ? 41.65600 -31.70600 21.64600  1.000 72.18831  ? 19  ARG H NE   1 
ATOM   233  C CZ   . ARG A 1 19  ? 41.75000 -33.02700 21.72600  1.000 80.28834  ? 19  ARG H CZ   1 
ATOM   234  N NH1  . ARG A 1 19  ? 41.38600 -33.80800 20.72200  1.000 85.37818  ? 19  ARG H NH1  1 
ATOM   235  N NH2  . ARG A 1 19  ? 42.22000 -33.57700 22.84200  1.000 78.49855  ? 19  ARG H NH2  1 
ATOM   236  H H    . ARG A 1 19  ? 40.68100 -26.44500 17.82800  1.000 31.64311  ? 19  ARG H H    1 
ATOM   237  H HA   . ARG A 1 19  ? 39.76600 -27.10900 20.28500  1.000 34.69194  ? 19  ARG H HA   1 
ATOM   238  H HB2  . ARG A 1 19  ? 39.77200 -29.16200 19.19600  1.000 44.35331  ? 19  ARG H HB2  1 
ATOM   239  H HB3  . ARG A 1 19  ? 41.28200 -28.93300 18.75900  1.000 44.35331  ? 19  ARG H HB3  1 
ATOM   240  H HG2  . ARG A 1 19  ? 41.97800 -29.16500 20.94800  1.000 52.00963  ? 19  ARG H HG2  1 
ATOM   241  H HG3  . ARG A 1 19  ? 40.47100 -29.30900 21.43200  1.000 52.00963  ? 19  ARG H HG3  1 
ATOM   242  H HD2  . ARG A 1 19  ? 40.27400 -31.31700 20.27400  1.000 74.55711  ? 19  ARG H HD2  1 
ATOM   243  H HD3  . ARG A 1 19  ? 41.76300 -31.16600 19.73800  1.000 74.55711  ? 19  ARG H HD3  1 
ATOM   244  H HE   . ARG A 1 19  ? 41.90300 -31.24400 22.32800  1.000 86.62954  ? 19  ARG H HE   1 
ATOM   245  H HH11 . ARG A 1 19  ? 41.08000 -33.46200 19.99700  1.000 102.45739 ? 19  ARG H HH11 1 
ATOM   246  H HH12 . ARG A 1 19  ? 41.45500 -34.66200 20.79500  1.000 102.45739 ? 19  ARG H HH12 1 
ATOM   247  H HH21 . ARG A 1 19  ? 42.45900 -33.07800 23.50100  1.000 94.20183  ? 19  ARG H HH21 1 
ATOM   248  H HH22 . ARG A 1 19  ? 42.28600 -34.43200 22.90500  1.000 94.20183  ? 19  ARG H HH22 1 
ATOM   249  N N    . LEU A 1 20  ? 41.66800 -25.80400 21.10600  1.000 27.78671  ? 20  LEU H N    1 
ATOM   250  C CA   . LEU A 1 20  ? 42.82200 -25.10200 21.64100  1.000 26.04577  ? 20  LEU H CA   1 
ATOM   251  C C    . LEU A 1 20  ? 43.07700 -25.56700 23.06600  1.000 26.46685  ? 20  LEU H C    1 
ATOM   252  O O    . LEU A 1 20  ? 42.14500 -25.91400 23.79800  1.000 26.91692  ? 20  LEU H O    1 
ATOM   253  C CB   . LEU A 1 20  ? 42.61300 -23.58600 21.62600  1.000 26.79722  ? 20  LEU H CB   1 
ATOM   254  C CG   . LEU A 1 20  ? 42.35000 -22.96000 20.25800  1.000 27.43748  ? 20  LEU H CG   1 
ATOM   255  C CD1  . LEU A 1 20  ? 41.94800 -21.51100 20.41700  1.000 25.93825  ? 20  LEU H CD1  1 
ATOM   256  C CD2  . LEU A 1 20  ? 43.57700 -23.08400 19.37800  1.000 28.21676  ? 20  LEU H CD2  1 
ATOM   257  H H    . LEU A 1 20  ? 40.94500 -25.66100 21.55000  1.000 33.34762  ? 20  LEU H H    1 
ATOM   258  H HA   . LEU A 1 20  ? 43.60400 -25.30200 21.10200  1.000 31.25849  ? 20  LEU H HA   1 
ATOM   259  H HB2  . LEU A 1 20  ? 41.84900 -23.38000 22.18800  1.000 32.16024  ? 20  LEU H HB2  1 
ATOM   260  H HB3  . LEU A 1 20  ? 43.41100 -23.16700 21.98500  1.000 32.16024  ? 20  LEU H HB3  1 
ATOM   261  H HG   . LEU A 1 20  ? 41.62100 -23.42900 19.82200  1.000 32.92854  ? 20  LEU H HG   1 
ATOM   262  H HD11 . LEU A 1 20  ? 41.78700 -21.13000 19.54000  1.000 31.12948  ? 20  LEU H HD11 1 
ATOM   263  H HD12 . LEU A 1 20  ? 41.13900 -21.46500 20.95100  1.000 31.12948  ? 20  LEU H HD12 1 
ATOM   264  H HD13 . LEU A 1 20  ? 42.66500 -21.03200 20.86000  1.000 31.12948  ? 20  LEU H HD13 1 
ATOM   265  H HD21 . LEU A 1 20  ? 43.43600 -22.57400 18.56500  1.000 33.86368  ? 20  LEU H HD21 1 
ATOM   266  H HD22 . LEU A 1 20  ? 44.34500 -22.73600 19.85700  1.000 33.86368  ? 20  LEU H HD22 1 
ATOM   267  H HD23 . LEU A 1 20  ? 43.71800 -24.01900 19.16200  1.000 33.86368  ? 20  LEU H HD23 1 
ATOM   268  N N    . SER A 1 21  ? 44.35000 -25.56500 23.45500  1.000 26.60680  ? 21  SER H N    1 
ATOM   269  C CA   . SER A 1 21  ? 44.74800 -25.96500 24.79500  1.000 29.43858  ? 21  SER H CA   1 
ATOM   270  C C    . SER A 1 21  ? 45.76300 -24.97200 25.33800  1.000 31.17861  ? 21  SER H C    1 
ATOM   271  O O    . SER A 1 21  ? 46.45100 -24.27900 24.58600  1.000 30.84826  ? 21  SER H O    1 
ATOM   272  C CB   . SER A 1 21  ? 45.34200 -27.37800 24.81100  1.000 29.32866  ? 21  SER H CB   1 
ATOM   273  O OG   . SER A 1 21  ? 44.38000 -28.33000 24.39900  1.000 33.62008  ? 21  SER H OG   1 
ATOM   274  H H    . SER A 1 21  ? 45.00700 -25.33200 22.95200  1.000 31.93173  ? 21  SER H H    1 
ATOM   275  H HA   . SER A 1 21  ? 43.96900 -25.95100 25.37400  1.000 35.32987  ? 21  SER H HA   1 
ATOM   276  H HB2  . SER A 1 21  ? 46.09900 -27.41000 24.20500  1.000 35.19797  ? 21  SER H HB2  1 
ATOM   277  H HB3  . SER A 1 21  ? 45.63000 -27.59000 25.71300  1.000 35.19797  ? 21  SER H HB3  1 
ATOM   278  H HG   . SER A 1 21  ? 43.74600 -28.35500 24.94900  1.000 40.34767  ? 21  SER H HG   1 
ATOM   279  N N    . CYS A 1 22  ? 45.84200 -24.90900 26.66400  1.000 33.05844  ? 22  CYS H N    1 
ATOM   280  C CA   . CYS A 1 22  ? 46.83700 -24.10500 27.35700  1.000 31.99669  ? 22  CYS H CA   1 
ATOM   281  C C    . CYS A 1 22  ? 47.44700 -24.95000 28.45800  1.000 33.51843  ? 22  CYS H C    1 
ATOM   282  O O    . CYS A 1 22  ? 46.72100 -25.56500 29.24500  1.000 30.90681  ? 22  CYS H O    1 
ATOM   283  C CB   . CYS A 1 22  ? 46.23700 -22.82900 27.94100  1.000 33.16779  ? 22  CYS H CB   1 
ATOM   284  S SG   . CYS A 1 22  ? 46.10600 -21.52000 26.71900  1.000 35.69927  ? 22  CYS H SG   1 
ATOM   285  H H    . CYS A 1 22  ? 45.31600 -25.33500 27.19500  1.000 39.67370  ? 22  CYS H H    1 
ATOM   286  H HA   . CYS A 1 22  ? 47.53300 -23.84100 26.73400  1.000 38.39960  ? 22  CYS H HA   1 
ATOM   287  H HB2  . CYS A 1 22  ? 45.34700 -23.02000 28.27600  1.000 39.80491  ? 22  CYS H HB2  1 
ATOM   288  H HB3  . CYS A 1 22  ? 46.80200 -22.51300 28.66300  1.000 39.80491  ? 22  CYS H HB3  1 
ATOM   289  N N    . THR A 1 23  ? 48.77100 -24.98200 28.50300  1.000 34.75829  ? 23  THR H N    1 
ATOM   290  C CA   . THR A 1 23  ? 49.52100 -25.77700 29.46400  1.000 35.91859  ? 23  THR H CA   1 
ATOM   291  C C    . THR A 1 23  ? 50.20400 -24.82600 30.43500  1.000 35.01813  ? 23  THR H C    1 
ATOM   292  O O    . THR A 1 23  ? 50.92700 -23.91600 30.01400  1.000 32.68688  ? 23  THR H O    1 
ATOM   293  C CB   . THR A 1 23  ? 50.53900 -26.66400 28.74900  1.000 33.22814  ? 23  THR H CB   1 
ATOM   294  O OG1  . THR A 1 23  ? 49.87900 -27.38600 27.70100  1.000 33.48842  ? 23  THR H OG1  1 
ATOM   295  C CG2  . THR A 1 23  ? 51.17200 -27.64900 29.71700  1.000 35.03901  ? 23  THR H CG2  1 
ATOM   296  H H    . THR A 1 23  ? 49.27500 -24.53600 27.96700  1.000 41.71351  ? 23  THR H H    1 
ATOM   297  H HA   . THR A 1 23  ? 48.92500 -26.35200 29.96800  1.000 43.10587  ? 23  THR H HA   1 
ATOM   298  H HB   . THR A 1 23  ? 51.24500 -26.11300 28.37600  1.000 39.87733  ? 23  THR H HB   1 
ATOM   299  H HG1  . THR A 1 23  ? 50.43000 -27.87700 27.29900  1.000 40.18967  ? 23  THR H HG1  1 
ATOM   300  H HG21 . THR A 1 23  ? 51.78800 -28.23100 29.24400  1.000 42.05038  ? 23  THR H HG21 1 
ATOM   301  H HG22 . THR A 1 23  ? 51.65900 -27.17100 30.40700  1.000 42.05038  ? 23  THR H HG22 1 
ATOM   302  H HG23 . THR A 1 23  ? 50.48500 -28.19200 30.13500  1.000 42.05038  ? 23  THR H HG23 1 
ATOM   303  N N    . ALA A 1 24  ? 49.95500 -25.02300 31.72400  1.000 36.19856  ? 24  ALA H N    1 
ATOM   304  C CA   . ALA A 1 24  ? 50.54000 -24.18700 32.75800  1.000 36.91763  ? 24  ALA H CA   1 
ATOM   305  C C    . ALA A 1 24  ? 51.90700 -24.71800 33.16600  1.000 34.94780  ? 24  ALA H C    1 
ATOM   306  O O    . ALA A 1 24  ? 52.16900 -25.92200 33.11200  1.000 34.89813  ? 24  ALA H O    1 
ATOM   307  C CB   . ALA A 1 24  ? 49.62500 -24.12600 33.98200  1.000 39.53910  ? 24  ALA H CB   1 
ATOM   308  H H    . ALA A 1 24  ? 49.44300 -25.64400 32.02700  1.000 43.44184  ? 24  ALA H H    1 
ATOM   309  H HA   . ALA A 1 24  ? 50.65200 -23.28600 32.41600  1.000 44.30472  ? 24  ALA H HA   1 
ATOM   310  H HB1  . ALA A 1 24  ? 50.06900 -23.62600 34.68400  1.000 47.45049  ? 24  ALA H HB1  1 
ATOM   311  H HB2  . ALA A 1 24  ? 48.79600 -23.68500 33.73600  1.000 47.45049  ? 24  ALA H HB2  1 
ATOM   312  H HB3  . ALA A 1 24  ? 49.44100 -25.02900 34.28500  1.000 47.45049  ? 24  ALA H HB3  1 
ATOM   313  N N    . SER A 1 25  ? 52.77800 -23.80100 33.58100  1.000 37.46810  ? 25  SER H N    1 
ATOM   314  C CA   . SER A 1 25  ? 54.08800 -24.15000 34.11300  1.000 39.98850  ? 25  SER H CA   1 
ATOM   315  C C    . SER A 1 25  ? 54.39100 -23.23300 35.28700  1.000 39.88788  ? 25  SER H C    1 
ATOM   316  O O    . SER A 1 25  ? 54.27200 -22.01000 35.16600  1.000 45.00924  ? 25  SER H O    1 
ATOM   317  C CB   . SER A 1 25  ? 55.17700 -24.01900 33.04500  1.000 42.35888  ? 25  SER H CB   1 
ATOM   318  O OG   . SER A 1 25  ? 55.39000 -22.66100 32.70600  1.000 48.09936  ? 25  SER H OG   1 
ATOM   319  H H    . SER A 1 25  ? 52.62800 -22.95500 33.56300  1.000 44.96529  ? 25  SER H H    1 
ATOM   320  H HA   . SER A 1 25  ? 54.08300 -25.06800 34.42500  1.000 47.98977  ? 25  SER H HA   1 
ATOM   321  H HB2  . SER A 1 25  ? 56.00400 -24.39200 33.39000  1.000 50.83423  ? 25  SER H HB2  1 
ATOM   322  H HB3  . SER A 1 25  ? 54.90100 -24.50300 32.25100  1.000 50.83423  ? 25  SER H HB3  1 
ATOM   323  H HG   . SER A 1 25  ? 54.74700 -22.19300 32.97700  1.000 57.72280  ? 25  SER H HG   1 
ATOM   324  N N    . GLY A 1 26  ? 54.78400 -23.82300 36.41500  1.000 37.33881  ? 26  GLY H N    1 
ATOM   325  C CA   . GLY A 1 26  ? 55.02400 -23.07400 37.63000  1.000 39.36850  ? 26  GLY H CA   1 
ATOM   326  C C    . GLY A 1 26  ? 53.82900 -22.94900 38.54800  1.000 37.52911  ? 26  GLY H C    1 
ATOM   327  O O    . GLY A 1 26  ? 53.91700 -22.24600 39.56400  1.000 37.80971  ? 26  GLY H O    1 
ATOM   328  H H    . GLY A 1 26  ? 54.91800 -24.66800 36.49600  1.000 44.81014  ? 26  GLY H H    1 
ATOM   329  H HA2  . GLY A 1 26  ? 55.73400 -23.50900 38.12700  1.000 47.24577  ? 26  GLY H HA2  1 
ATOM   330  H HA3  . GLY A 1 26  ? 55.30800 -22.17800 37.39100  1.000 47.24577  ? 26  GLY H HA3  1 
ATOM   331  N N    . PHE A 1 27  ? 52.71700 -23.59500 38.22400  1.000 35.69762  ? 27  PHE H N    1 
ATOM   332  C CA   . PHE A 1 27  ? 51.51900 -23.57800 39.05700  1.000 38.27843  ? 27  PHE H CA   1 
ATOM   333  C C    . PHE A 1 27  ? 50.57000 -24.63100 38.49500  1.000 40.22883  ? 27  PHE H C    1 
ATOM   334  O O    . PHE A 1 27  ? 50.89600 -25.33800 37.53600  1.000 39.11800  ? 27  PHE H O    1 
ATOM   335  C CB   . PHE A 1 27  ? 50.88400 -22.18500 39.10300  1.000 38.64916  ? 27  PHE H CB   1 
ATOM   336  C CG   . PHE A 1 27  ? 50.33800 -21.71700 37.78400  1.000 39.02782  ? 27  PHE H CG   1 
ATOM   337  C CD1  . PHE A 1 27  ? 51.17400 -21.17000 36.82300  1.000 42.40923  ? 27  PHE H CD1  1 
ATOM   338  C CD2  . PHE A 1 27  ? 48.98500 -21.81600 37.50800  1.000 39.80752  ? 27  PHE H CD2  1 
ATOM   339  C CE1  . PHE A 1 27  ? 50.67100 -20.73900 35.60500  1.000 39.10774  ? 27  PHE H CE1  1 
ATOM   340  C CE2  . PHE A 1 27  ? 48.47600 -21.38500 36.29600  1.000 40.97851  ? 27  PHE H CE2  1 
ATOM   341  C CZ   . PHE A 1 27  ? 49.32100 -20.84500 35.34400  1.000 37.76633  ? 27  PHE H CZ   1 
ATOM   342  H H    . PHE A 1 27  ? 52.62800 -24.06400 37.50800  1.000 42.84072  ? 27  PHE H H    1 
ATOM   343  H HA   . PHE A 1 27  ? 51.74600 -23.82500 39.96700  1.000 45.93769  ? 27  PHE H HA   1 
ATOM   344  H HB2  . PHE A 1 27  ? 50.15100 -22.19900 39.73800  1.000 46.38256  ? 27  PHE H HB2  1 
ATOM   345  H HB3  . PHE A 1 27  ? 51.55700 -21.54600 39.38700  1.000 46.38256  ? 27  PHE H HB3  1 
ATOM   346  H HD1  . PHE A 1 27  ? 52.08400 -21.09100 36.99700  1.000 50.89464  ? 27  PHE H HD1  1 
ATOM   347  H HD2  . PHE A 1 27  ? 48.41200 -22.17600 38.14500  1.000 47.77260  ? 27  PHE H HD2  1 
ATOM   348  H HE1  . PHE A 1 27  ? 51.24200 -20.37900 34.96600  1.000 46.93286  ? 27  PHE H HE1  1 
ATOM   349  H HE2  . PHE A 1 27  ? 47.56600 -21.45800 36.12100  1.000 49.17778  ? 27  PHE H HE2  1 
ATOM   350  H HZ   . PHE A 1 27  ? 48.98000 -20.55400 34.52900  1.000 45.32317  ? 27  PHE H HZ   1 
ATOM   351  N N    . SER A 1 28  ? 49.38900 -24.73100 39.09900  1.000 37.66759  ? 28  SER H N    1 
ATOM   352  C CA   . SER A 1 28  ? 48.41800 -25.76200 38.76100  1.000 38.56848  ? 28  SER H CA   1 
ATOM   353  C C    . SER A 1 28  ? 47.14700 -25.12700 38.21900  1.000 39.00804  ? 28  SER H C    1 
ATOM   354  O O    . SER A 1 28  ? 46.60000 -24.20300 38.83100  1.000 38.73753  ? 28  SER H O    1 
ATOM   355  C CB   . SER A 1 28  ? 48.09500 -26.62500 39.98500  1.000 39.43839  ? 28  SER H CB   1 
ATOM   356  O OG   . SER A 1 28  ? 49.26700 -27.23300 40.49600  1.000 49.14696  ? 28  SER H OG   1 
ATOM   357  H H    . SER A 1 28  ? 49.12400 -24.20000 39.72200  1.000 45.20467  ? 28  SER H H    1 
ATOM   358  H HA   . SER A 1 28  ? 48.78600 -26.32900 38.06400  1.000 46.28575  ? 28  SER H HA   1 
ATOM   359  H HB2  . SER A 1 28  ? 47.70500 -26.06300 40.67300  1.000 47.32964  ? 28  SER H HB2  1 
ATOM   360  H HB3  . SER A 1 28  ? 47.46700 -27.31700 39.72600  1.000 47.32964  ? 28  SER H HB3  1 
ATOM   361  H HG   . SER A 1 28  ? 49.07100 -27.74600 41.13200  1.000 58.97992  ? 28  SER H HG   1 
ATOM   362  N N    . ILE A 1 29  ? 46.67400 -25.63500 37.07700  1.000 40.15750  ? 29  ILE H N    1 
ATOM   363  C CA   . ILE A 1 29  ? 45.41100 -25.15300 36.52800  1.000 41.47824  ? 29  ILE H CA   1 
ATOM   364  C C    . ILE A 1 29  ? 44.23000 -25.67500 37.33800  1.000 42.09854  ? 29  ILE H C    1 
ATOM   365  O O    . ILE A 1 29  ? 43.18500 -25.01700 37.41500  1.000 42.78860  ? 29  ILE H O    1 
ATOM   366  C CB   . ILE A 1 29  ? 45.26400 -25.53800 35.04000  1.000 41.94784  ? 29  ILE H CB   1 
ATOM   367  C CG1  . ILE A 1 29  ? 45.42800 -27.04900 34.82200  1.000 47.15851  ? 29  ILE H CG1  1 
ATOM   368  C CG2  . ILE A 1 29  ? 46.25700 -24.75500 34.19200  1.000 41.94837  ? 29  ILE H CG2  1 
ATOM   369  C CD1  . ILE A 1 29  ? 44.12700 -27.84300 34.89300  1.000 43.88821  ? 29  ILE H CD1  1 
ATOM   370  H H    A ILE A 1 29  ? 47.05900 -26.24600 36.61100  0.530 48.19257  ? 29  ILE H H    1 
ATOM   371  H H    B ILE A 1 29  ? 47.05900 -26.24600 36.61100  0.470 48.19257  ? 29  ILE H H    1 
ATOM   372  H HA   . ILE A 1 29  ? 45.42300 -24.18500 36.58600  1.000 49.77745  ? 29  ILE H HA   1 
ATOM   373  H HB   . ILE A 1 29  ? 44.36400 -25.30600 34.76300  1.000 50.34098  ? 29  ILE H HB   1 
ATOM   374  H HG12 . ILE A 1 29  ? 45.81300 -27.19500 33.94400  1.000 56.59379  ? 29  ILE H HG12 1 
ATOM   375  H HG13 . ILE A 1 29  ? 46.02100 -27.39700 35.50600  1.000 56.59379  ? 29  ILE H HG13 1 
ATOM   376  H HG21 . ILE A 1 29  ? 46.12100 -24.97800 33.25800  1.000 50.34162  ? 29  ILE H HG21 1 
ATOM   377  H HG22 . ILE A 1 29  ? 46.11000 -23.80600 34.33000  1.000 50.34162  ? 29  ILE H HG22 1 
ATOM   378  H HG23 . ILE A 1 29  ? 47.15800 -24.99300 34.46100  1.000 50.34162  ? 29  ILE H HG23 1 
ATOM   379  H HD11 . ILE A 1 29  ? 44.28700 -28.74200 34.56500  1.000 52.66943  ? 29  ILE H HD11 1 
ATOM   380  H HD12 . ILE A 1 29  ? 43.82600 -27.87600 35.81400  1.000 52.66943  ? 29  ILE H HD12 1 
ATOM   381  H HD13 . ILE A 1 29  ? 43.45900 -27.40500 34.34200  1.000 52.66943  ? 29  ILE H HD13 1 
ATOM   382  N N    . ASP A 1 30  ? 44.36200 -26.85100 37.95100  1.000 40.14690  ? 30  ASP H N    1 
ATOM   383  C CA   . ASP A 1 30  ? 43.24100 -27.42700 38.68500  1.000 42.36822  ? 30  ASP H CA   1 
ATOM   384  C C    . ASP A 1 30  ? 42.95900 -26.70500 39.99700  1.000 42.32863  ? 30  ASP H C    1 
ATOM   385  O O    . ASP A 1 30  ? 42.02200 -27.09700 40.70300  1.000 42.85868  ? 30  ASP H O    1 
ATOM   386  C CB   . ASP A 1 30  ? 43.49500 -28.91700 38.94700  1.000 41.94813  ? 30  ASP H CB   1 
ATOM   387  C CG   . ASP A 1 30  ? 44.80200 -29.17500 39.68000  1.000 43.90767  ? 30  ASP H CG   1 
ATOM   388  O OD1  . ASP A 1 30  ? 45.35300 -28.22900 40.28200  1.000 42.16791  ? 30  ASP H OD1  1 
ATOM   389  O OD2  . ASP A 1 30  ? 45.28400 -30.33000 39.64900  1.000 45.20928  ? 30  ASP H OD2  1 
ATOM   390  H H    . ASP A 1 30  ? 45.07900 -27.32600 37.95500  1.000 48.17985  ? 30  ASP H H    1 
ATOM   391  H HA   . ASP A 1 30  ? 42.44400 -27.35700 38.13700  1.000 50.84543  ? 30  ASP H HA   1 
ATOM   392  H HB2  . ASP A 1 30  ? 42.77200 -29.26900 39.49000  1.000 50.34132  ? 30  ASP H HB2  1 
ATOM   393  H HB3  . ASP A 1 30  ? 43.53000 -29.38500 38.09800  1.000 50.34132  ? 30  ASP H HB3  1 
ATOM   394  N N    . SER A 1 31  ? 43.72300 -25.66200 40.33000  1.000 38.47723  ? 31  SER H N    1 
ATOM   395  C CA   . SER A 1 31  ? 43.54000 -24.92500 41.57400  1.000 39.80755  ? 31  SER H CA   1 
ATOM   396  C C    . SER A 1 31  ? 43.15400 -23.46600 41.35000  1.000 42.98868  ? 31  SER H C    1 
ATOM   397  O O    . SER A 1 31  ? 43.10700 -22.69500 42.31700  1.000 40.12698  ? 31  SER H O    1 
ATOM   398  C CB   . SER A 1 31  ? 44.81700 -25.00000 42.41900  1.000 40.67824  ? 31  SER H CB   1 
ATOM   399  O OG   . SER A 1 31  ? 45.80600 -24.10600 41.93600  1.000 40.76736  ? 31  SER H OG   1 
ATOM   400  H H    . SER A 1 31  ? 44.36300 -25.36000 39.84100  1.000 46.17624  ? 31  SER H H    1 
ATOM   401  H HA   . SER A 1 31  ? 42.81900 -25.34100 42.07200  1.000 47.77263  ? 31  SER H HA   1 
ATOM   402  H HB2  . SER A 1 31  ? 44.60200 -24.76500 43.33500  1.000 48.81745  ? 31  SER H HB2  1 
ATOM   403  H HB3  . SER A 1 31  ? 45.16600 -25.90400 42.38100  1.000 48.81745  ? 31  SER H HB3  1 
ATOM   404  H HG   . SER A 1 31  ? 46.57200 -24.42500 42.06900  1.000 48.92440  ? 31  SER H HG   1 
ATOM   405  N N    . TYR A 1 32  ? 42.87800 -23.06600 40.10900  1.000 40.11690  ? 32  TYR H N    1 
ATOM   406  C CA   . TYR A 1 32  ? 42.45400 -21.70900 39.80400  1.000 38.12846  ? 32  TYR H CA   1 
ATOM   407  C C    . TYR A 1 32  ? 41.37200 -21.73900 38.73400  1.000 36.68887  ? 32  TYR H C    1 
ATOM   408  O O    . TYR A 1 32  ? 41.16800 -22.74600 38.05000  1.000 34.46748  ? 32  TYR H O    1 
ATOM   409  C CB   . TYR A 1 32  ? 43.61100 -20.83700 39.30600  1.000 38.99901  ? 32  TYR H CB   1 
ATOM   410  C CG   . TYR A 1 32  ? 44.68800 -20.56300 40.31900  1.000 40.82780  ? 32  TYR H CG   1 
ATOM   411  C CD1  . TYR A 1 32  ? 44.61500 -19.45600 41.15100  1.000 41.03818  ? 32  TYR H CD1  1 
ATOM   412  C CD2  . TYR A 1 32  ? 45.79300 -21.39600 40.42800  1.000 41.09746  ? 32  TYR H CD2  1 
ATOM   413  C CE1  . TYR A 1 32  ? 45.60300 -19.19200 42.07200  1.000 43.12827  ? 32  TYR H CE1  1 
ATOM   414  C CE2  . TYR A 1 32  ? 46.78800 -21.14000 41.34700  1.000 45.13806  ? 32  TYR H CE2  1 
ATOM   415  C CZ   . TYR A 1 32  ? 46.68700 -20.03600 42.16700  1.000 45.79787  ? 32  TYR H CZ   1 
ATOM   416  O OH   . TYR A 1 32  ? 47.67400 -19.77200 43.08700  1.000 51.18857  ? 32  TYR H OH   1 
ATOM   417  H H    . TYR A 1 32  ? 42.93000 -23.57500 39.41700  1.000 48.14385  ? 32  TYR H H    1 
ATOM   418  H HA   . TYR A 1 32  ? 42.09200 -21.32500 40.61800  1.000 45.75772  ? 32  TYR H HA   1 
ATOM   419  H HB2  . TYR A 1 32  ? 44.02800 -21.28400 38.55300  1.000 46.80238  ? 32  TYR H HB2  1 
ATOM   420  H HB3  . TYR A 1 32  ? 43.25100 -19.98100 39.02600  1.000 46.80238  ? 32  TYR H HB3  1 
ATOM   421  H HD1  . TYR A 1 32  ? 43.88600 -18.88200 41.08500  1.000 49.24939  ? 32  TYR H HD1  1 
ATOM   422  H HD2  . TYR A 1 32  ? 45.86300 -22.13800 39.87200  1.000 49.32052  ? 32  TYR H HD2  1 
ATOM   423  H HE1  . TYR A 1 32  ? 45.53900 -18.44800 42.62600  1.000 51.75749  ? 32  TYR H HE1  1 
ATOM   424  H HE2  . TYR A 1 32  ? 47.52200 -21.70800 41.41400  1.000 54.16925  ? 32  TYR H HE2  1 
ATOM   425  H HH   . TYR A 1 32  ? 47.51400 -19.04700 43.47900  1.000 61.42985  ? 32  TYR H HH   1 
ATOM   426  N N    . GLY A 1 33  ? 40.68800 -20.60800 38.58300  1.000 32.41749  ? 33  GLY H N    1 
ATOM   427  C CA   . GLY A 1 33  ? 39.70400 -20.45100 37.53000  1.000 31.07813  ? 33  GLY H CA   1 
ATOM   428  C C    . GLY A 1 33  ? 40.33200 -19.78600 36.31600  1.000 29.06780  ? 33  GLY H C    1 
ATOM   429  O O    . GLY A 1 33  ? 41.14500 -18.87300 36.44200  1.000 27.96693  ? 33  GLY H O    1 
ATOM   430  H H    . GLY A 1 33  ? 40.78000 -19.91500 39.08400  1.000 38.90456  ? 33  GLY H H    1 
ATOM   431  H HA2  . GLY A 1 33  ? 39.35800 -21.31900 37.26900  1.000 37.29733  ? 33  GLY H HA2  1 
ATOM   432  H HA3  . GLY A 1 33  ? 38.97000 -19.90000 37.84400  1.000 37.29733  ? 33  GLY H HA3  1 
ATOM   433  N N    . PHE A 1 34  ? 39.94500 -20.26400 35.13400  1.000 30.38944  ? 34  PHE H N    1 
ATOM   434  C CA   . PHE A 1 34  ? 40.50600 -19.78700 33.87900  1.000 24.72643  ? 34  PHE H CA   1 
ATOM   435  C C    . PHE A 1 34  ? 39.39900 -19.53300 32.87200  1.000 25.22756  ? 34  PHE H C    1 
ATOM   436  O O    . PHE A 1 34  ? 38.46100 -20.32500 32.74900  1.000 24.86735  ? 34  PHE H O    1 
ATOM   437  C CB   . PHE A 1 34  ? 41.51100 -20.78800 33.30900  1.000 28.39874  ? 34  PHE H CB   1 
ATOM   438  C CG   . PHE A 1 34  ? 42.75600 -20.89800 34.12400  1.000 29.91797  ? 34  PHE H CG   1 
ATOM   439  C CD1  . PHE A 1 34  ? 43.79800 -20.00800 33.93900  1.000 29.05758  ? 34  PHE H CD1  1 
ATOM   440  C CD2  . PHE A 1 34  ? 42.87200 -21.86800 35.10200  1.000 35.32879  ? 34  PHE H CD2  1 
ATOM   441  C CE1  . PHE A 1 34  ? 44.94100 -20.09500 34.70200  1.000 31.56809  ? 34  PHE H CE1  1 
ATOM   442  C CE2  . PHE A 1 34  ? 44.01100 -21.96000 35.86700  1.000 34.49747  ? 34  PHE H CE2  1 
ATOM   443  C CZ   . PHE A 1 34  ? 45.04600 -21.07200 35.66900  1.000 34.80844  ? 34  PHE H CZ   1 
ATOM   444  H H    . PHE A 1 34  ? 39.34800 -20.87600 35.03500  1.000 36.47089  ? 34  PHE H H    1 
ATOM   445  H HA   . PHE A 1 34  ? 40.96100 -18.94500 34.03300  1.000 29.67528  ? 34  PHE H HA   1 
ATOM   446  H HB2  . PHE A 1 34  ? 41.09700 -21.66500 33.27600  1.000 34.08206  ? 34  PHE H HB2  1 
ATOM   447  H HB3  . PHE A 1 34  ? 41.76300 -20.50700 32.41600  1.000 34.08206  ? 34  PHE H HB3  1 
ATOM   448  H HD1  . PHE A 1 34  ? 43.72600 -19.34300 33.29300  1.000 34.87267  ? 34  PHE H HD1  1 
ATOM   449  H HD2  . PHE A 1 34  ? 42.17300 -22.46400 35.24400  1.000 42.39812  ? 34  PHE H HD2  1 
ATOM   450  H HE1  . PHE A 1 34  ? 45.63900 -19.49700 34.56600  1.000 37.88528  ? 34  PHE H HE1  1 
ATOM   451  H HE2  . PHE A 1 34  ? 44.08200 -22.62100 36.51700  1.000 41.40053  ? 34  PHE H HE2  1 
ATOM   452  H HZ   . PHE A 1 34  ? 45.81600 -21.13200 36.18800  1.000 41.77370  ? 34  PHE H HZ   1 
ATOM   453  N N    . SER A 1 35  ? 39.52400 -18.42500 32.15400  1.000 23.15702  ? 35  SER H N    1 
ATOM   454  C CA   . SER A 1 35  ? 38.59000 -18.04000 31.11100  1.000 24.55836  ? 35  SER H CA   1 
ATOM   455  C C    . SER A 1 35  ? 39.18300 -18.33300 29.73700  1.000 22.62704  ? 35  SER H C    1 
ATOM   456  O O    . SER A 1 35  ? 40.39400 -18.50100 29.57600  1.000 22.63658  ? 35  SER H O    1 
ATOM   457  C CB   . SER A 1 35  ? 38.24600 -16.55100 31.22100  1.000 23.99869  ? 35  SER H CB   1 
ATOM   458  O OG   . SER A 1 35  ? 37.55800 -16.26000 32.42500  1.000 26.31985  ? 35  SER H OG   1 
ATOM   459  H H    . SER A 1 35  ? 40.16500 -17.86100 32.25800  1.000 27.79200  ? 35  SER H H    1 
ATOM   460  H HA   . SER A 1 35  ? 37.77100 -18.55100 31.20700  1.000 29.47360  ? 35  SER H HA   1 
ATOM   461  H HB2  . SER A 1 35  ? 39.06900 -16.03800 31.19900  1.000 28.80200  ? 35  SER H HB2  1 
ATOM   462  H HB3  . SER A 1 35  ? 37.68200 -16.30500 30.47100  1.000 28.80200  ? 35  SER H HB3  1 
ATOM   463  H HG   . SER A 1 35  ? 36.79800 -16.61800 32.41500  1.000 31.58739  ? 35  SER H HG   1 
ATOM   464  N N    . TRP A 1 36  ? 38.30300 -18.41500 28.74600  1.000 23.75899  ? 36  TRP H N    1 
ATOM   465  C CA   . TRP A 1 36  ? 38.68200 -18.33500 27.34300  1.000 22.84801  ? 36  TRP H CA   1 
ATOM   466  C C    . TRP A 1 36  ? 38.08200 -17.06000 26.77500  1.000 20.52719  ? 36  TRP H C    1 
ATOM   467  O O    . TRP A 1 36  ? 36.90600 -16.76000 27.01500  1.000 19.76661  ? 36  TRP H O    1 
ATOM   468  C CB   . TRP A 1 36  ? 38.21200 -19.55800 26.55900  1.000 23.32739  ? 36  TRP H CB   1 
ATOM   469  C CG   . TRP A 1 36  ? 39.09200 -20.74500 26.78600  1.000 24.53769  ? 36  TRP H CG   1 
ATOM   470  C CD1  . TRP A 1 36  ? 38.91000 -21.73600 27.70600  1.000 25.14753  ? 36  TRP H CD1  1 
ATOM   471  C CD2  . TRP A 1 36  ? 40.30700 -21.05800 26.09400  1.000 24.00677  ? 36  TRP H CD2  1 
ATOM   472  N NE1  . TRP A 1 36  ? 39.93100 -22.65000 27.62400  1.000 25.62743  ? 36  TRP H NE1  1 
ATOM   473  C CE2  . TRP A 1 36  ? 40.80300 -22.25600 26.64400  1.000 25.94774  ? 36  TRP H CE2  1 
ATOM   474  C CE3  . TRP A 1 36  ? 41.02300 -20.44200 25.06300  1.000 26.24887  ? 36  TRP H CE3  1 
ATOM   475  C CZ2  . TRP A 1 36  ? 41.98000 -22.85300 26.19600  1.000 26.46702  ? 36  TRP H CZ2  1 
ATOM   476  C CZ3  . TRP A 1 36  ? 42.18900 -21.03800 24.61600  1.000 25.08697  ? 36  TRP H CZ3  1 
ATOM   477  C CH2  . TRP A 1 36  ? 42.65600 -22.23100 25.18300  1.000 26.71714  ? 36  TRP H CH2  1 
ATOM   478  H H    . TRP A 1 36  ? 37.45800 -18.52000 28.86600  1.000 28.51436  ? 36  TRP H H    1 
ATOM   479  H HA   . TRP A 1 36  ? 39.64700 -18.30200 27.25500  1.000 27.42118  ? 36  TRP H HA   1 
ATOM   480  H HB2  . TRP A 1 36  ? 37.31300 -19.78900 26.83900  1.000 27.99644  ? 36  TRP H HB2  1 
ATOM   481  H HB3  . TRP A 1 36  ? 38.22200 -19.35000 25.61100  1.000 27.99644  ? 36  TRP H HB3  1 
ATOM   482  H HD1  . TRP A 1 36  ? 38.19800 -21.78500 28.30200  1.000 30.18061  ? 36  TRP H HD1  1 
ATOM   483  H HE1  . TRP A 1 36  ? 40.01100 -23.35600 28.11000  1.000 30.75648  ? 36  TRP H HE1  1 
ATOM   484  H HE3  . TRP A 1 36  ? 40.72100 -19.64800 24.68400  1.000 31.50222  ? 36  TRP H HE3  1 
ATOM   485  H HZ2  . TRP A 1 36  ? 42.29300 -23.64400 26.57100  1.000 31.76399  ? 36  TRP H HZ2  1 
ATOM   486  H HZ3  . TRP A 1 36  ? 42.67100 -20.63900 23.92800  1.000 30.10793  ? 36  TRP H HZ3  1 
ATOM   487  H HH2  . TRP A 1 36  ? 43.44400 -22.60800 24.86400  1.000 32.06414  ? 36  TRP H HH2  1 
ATOM   488  N N    A VAL A 1 37  ? 38.89300 -16.31900 26.02300  0.380 20.01170  ? 37  VAL H N    1 
ATOM   489  N N    B VAL A 1 37  ? 38.89300 -16.29700 26.05200  0.620 20.39386  ? 37  VAL H N    1 
ATOM   490  C CA   A VAL A 1 37  ? 38.52000 -15.02400 25.46200  0.380 19.06687  ? 37  VAL H CA   1 
ATOM   491  C CA   B VAL A 1 37  ? 38.45600 -15.05100 25.44300  0.620 18.99761  ? 37  VAL H CA   1 
ATOM   492  C C    A VAL A 1 37  ? 38.98300 -14.99300 24.01300  0.380 17.88512  ? 37  VAL H C    1 
ATOM   493  C C    B VAL A 1 37  ? 38.94600 -15.03400 24.00500  0.620 17.69769  ? 37  VAL H C    1 
ATOM   494  O O    A VAL A 1 37  ? 40.04000 -15.53800 23.68000  0.380 18.63451  ? 37  VAL H O    1 
ATOM   495  O O    B VAL A 1 37  ? 39.97900 -15.62200 23.67400  0.620 17.42888  ? 37  VAL H O    1 
ATOM   496  C CB   A VAL A 1 37  ? 39.15400 -13.86800 26.26300  0.380 19.69789  ? 37  VAL H CB   1 
ATOM   497  C CB   B VAL A 1 37  ? 38.97400 -13.81400 26.20700  0.620 19.72789  ? 37  VAL H CB   1 
ATOM   498  C CG1  A VAL A 1 37  ? 38.81100 -12.52500 25.64300  0.380 19.36773  ? 37  VAL H CG1  1 
ATOM   499  C CG1  B VAL A 1 37  ? 38.45600 -13.81400 27.64000  0.620 20.28786  ? 37  VAL H CG1  1 
ATOM   500  C CG2  A VAL A 1 37  ? 38.70800 -13.91800 27.71800  0.380 20.27788  ? 37  VAL H CG2  1 
ATOM   501  C CG2  B VAL A 1 37  ? 40.48900 -13.77400 26.18400  0.620 18.52668  ? 37  VAL H CG2  1 
ATOM   502  H H    A VAL A 1 37  ? 39.69400 -16.55500 25.81600  0.380 24.01761  ? 37  VAL H H    1 
ATOM   503  H H    B VAL A 1 37  ? 39.71800 -16.48600 25.89800  0.620 24.47620  ? 37  VAL H H    1 
ATOM   504  H HA   A VAL A 1 37  ? 37.55600 -14.91900 25.48400  0.380 22.88381  ? 37  VAL H HA   1 
ATOM   505  H HA   B VAL A 1 37  ? 37.48600 -15.01400 25.44600  0.620 22.80071  ? 37  VAL H HA   1 
ATOM   506  H HB   A VAL A 1 37  ? 40.11900 -13.96800 26.23800  0.380 23.64104  ? 37  VAL H HB   1 
ATOM   507  H HB   B VAL A 1 37  ? 38.64500 -13.01300 25.77000  0.620 23.67704  ? 37  VAL H HB   1 
ATOM   508  H HG11 A VAL A 1 37  ? 39.15200 -11.81800 26.21200  0.380 23.24484  ? 37  VAL H HG11 1 
ATOM   509  H HG11 B VAL A 1 37  ? 38.84100 -13.06100 28.11500  0.620 24.34901  ? 37  VAL H HG11 1 
ATOM   510  H HG12 A VAL A 1 37  ? 39.21800 -12.46900 24.76500  0.380 23.24484  ? 37  VAL H HG12 1 
ATOM   511  H HG12 B VAL A 1 37  ? 37.48900 -13.73700 27.62600  0.620 24.34901  ? 37  VAL H HG12 1 
ATOM   512  H HG13 A VAL A 1 37  ? 37.84700 -12.45000 25.56600  0.380 23.24484  ? 37  VAL H HG13 1 
ATOM   513  H HG13 B VAL A 1 37  ? 38.71600 -14.64400 28.07000  0.620 24.34901  ? 37  VAL H HG13 1 
ATOM   514  H HG21 A VAL A 1 37  ? 39.13500 -13.19600 28.20500  0.380 24.33703  ? 37  VAL H HG21 1 
ATOM   515  H HG21 B VAL A 1 37  ? 40.79500 -13.04400 26.74500  0.620 22.23558  ? 37  VAL H HG21 1 
ATOM   516  H HG22 A VAL A 1 37  ? 37.74400 -13.81800 27.75700  0.380 24.33703  ? 37  VAL H HG22 1 
ATOM   517  H HG22 B VAL A 1 37  ? 40.83200 -14.61600 26.52200  0.620 22.23558  ? 37  VAL H HG22 1 
ATOM   518  H HG23 A VAL A 1 37  ? 38.96800 -14.77200 28.09900  0.380 24.33703  ? 37  VAL H HG23 1 
ATOM   519  H HG23 B VAL A 1 37  ? 40.78800 -13.63800 25.27100  0.620 22.23558  ? 37  VAL H HG23 1 
ATOM   520  N N    . ARG A 1 38  ? 38.19600 -14.35300 23.14700  1.000 17.68645  ? 38  ARG H N    1 
ATOM   521  C CA   . ARG A 1 38  ? 38.56500 -14.21600 21.74700  1.000 17.03723  ? 38  ARG H CA   1 
ATOM   522  C C    . ARG A 1 38  ? 38.38600 -12.77500 21.29800  1.000 15.18478  ? 38  ARG H C    1 
ATOM   523  O O    . ARG A 1 38  ? 37.62200 -12.00400 21.88000  1.000 17.81773  ? 38  ARG H O    1 
ATOM   524  C CB   . ARG A 1 38  ? 37.74900 -15.14400 20.83900  1.000 16.00682  ? 38  ARG H CB   1 
ATOM   525  C CG   . ARG A 1 38  ? 36.30500 -14.73600 20.63300  1.000 17.43568  ? 38  ARG H CG   1 
ATOM   526  C CD   . ARG A 1 38  ? 35.60500 -15.70800 19.69500  1.000 21.22862  ? 38  ARG H CD   1 
ATOM   527  N NE   . ARG A 1 38  ? 34.31000 -15.19700 19.26800  1.000 22.19748  ? 38  ARG H NE   1 
ATOM   528  C CZ   . ARG A 1 38  ? 33.47300 -15.84400 18.46900  1.000 24.97875  ? 38  ARG H CZ   1 
ATOM   529  N NH1  . ARG A 1 38  ? 33.76900 -17.03500 17.97400  1.000 23.51782  ? 38  ARG H NH1  1 
ATOM   530  N NH2  . ARG A 1 38  ? 32.30700 -15.28100 18.16300  1.000 28.63984  ? 38  ARG H NH2  1 
ATOM   531  H H    A ARG A 1 38  ? 37.44400 -13.99000 23.35200  0.380 21.22731  ? 38  ARG H H    1 
ATOM   532  H H    B ARG A 1 38  ? 37.46200 -13.95700 23.35600  0.620 21.22731  ? 38  ARG H H    1 
ATOM   533  H HA   . ARG A 1 38  ? 39.50200 -14.44900 21.65400  1.000 20.44825  ? 38  ARG H HA   1 
ATOM   534  H HB2  . ARG A 1 38  ? 38.17100 -15.16700 19.96600  1.000 19.21175  ? 38  ARG H HB2  1 
ATOM   535  H HB3  . ARG A 1 38  ? 37.74700 -16.03100 21.23100  1.000 19.21175  ? 38  ARG H HB3  1 
ATOM   536  H HG2  . ARG A 1 38  ? 35.84100 -14.74100 21.48500  1.000 20.92638  ? 38  ARG H HG2  1 
ATOM   537  H HG3  . ARG A 1 38  ? 36.27000 -13.85000 20.24100  1.000 20.92638  ? 38  ARG H HG3  1 
ATOM   538  H HD2  . ARG A 1 38  ? 36.15400 -15.84500 18.90700  1.000 25.47791  ? 38  ARG H HD2  1 
ATOM   539  H HD3  . ARG A 1 38  ? 35.46500 -16.55100 20.15300  1.000 25.47791  ? 38  ARG H HD3  1 
ATOM   540  H HE   . ARG A 1 38  ? 34.07100 -14.42300 19.55500  1.000 26.64055  ? 38  ARG H HE   1 
ATOM   541  H HH11 . ARG A 1 38  ? 34.51900 -17.40700 18.16900  1.000 28.22495  ? 38  ARG H HH11 1 
ATOM   542  H HH12 . ARG A 1 38  ? 33.21100 -17.43600 17.45700  1.000 28.22495  ? 38  ARG H HH12 1 
ATOM   543  H HH21 . ARG A 1 38  ? 32.10500 -14.50900 18.48300  1.000 34.37138  ? 38  ARG H HH21 1 
ATOM   544  H HH22 . ARG A 1 38  ? 31.75500 -15.69000 17.64600  1.000 34.37138  ? 38  ARG H HH22 1 
ATOM   545  N N    . GLN A 1 39  ? 39.09900 -12.43500 20.23000  1.000 15.84638  ? 39  GLN H N    1 
ATOM   546  C CA   . GLN A 1 39  ? 39.09400 -11.08600 19.67800  1.000 18.27874  ? 39  GLN H CA   1 
ATOM   547  C C    . GLN A 1 39  ? 39.18100 -11.21000 18.16600  1.000 17.32680  ? 39  GLN H C    1 
ATOM   548  O O    . GLN A 1 39  ? 40.20600 -11.64900 17.63700  1.000 15.78371  ? 39  GLN H O    1 
ATOM   549  C CB   . GLN A 1 39  ? 40.25800 -10.27100 20.23000  1.000 17.71616  ? 39  GLN H CB   1 
ATOM   550  C CG   . GLN A 1 39  ? 40.32700 -8.86300  19.70800  1.000 20.43860  ? 39  GLN H CG   1 
ATOM   551  C CD   . GLN A 1 39  ? 41.35100 -8.03800  20.45400  1.000 22.83879  ? 39  GLN H CD   1 
ATOM   552  O OE1  . GLN A 1 39  ? 42.44800 -8.51000  20.75500  1.000 21.81827  ? 39  GLN H OE1  1 
ATOM   553  N NE2  . GLN A 1 39  ? 40.99500 -6.79900  20.76600  1.000 21.47793  ? 39  GLN H NE2  1 
ATOM   554  H H    . GLN A 1 39  ? 39.60500 -12.98000 19.79900  1.000 19.01923  ? 39  GLN H H    1 
ATOM   555  H HA   . GLN A 1 39  ? 38.26700 -10.63400 19.90500  1.000 21.93805  ? 39  GLN H HA   1 
ATOM   556  H HB2  . GLN A 1 39  ? 40.17200 -10.22300 21.19500  1.000 21.26296  ? 39  GLN H HB2  1 
ATOM   557  H HB3  . GLN A 1 39  ? 41.08700 -10.71500 19.99200  1.000 21.26296  ? 39  GLN H HB3  1 
ATOM   558  H HG2  . GLN A 1 39  ? 40.57700 -8.88200  18.77000  1.000 24.52989  ? 39  GLN H HG2  1 
ATOM   559  H HG3  . GLN A 1 39  ? 39.46100 -8.44000  19.81200  1.000 24.52989  ? 39  GLN H HG3  1 
ATOM   560  H HE21 . GLN A 1 39  ? 40.21700 -6.50600  20.54300  1.000 25.77709  ? 39  GLN H HE21 1 
ATOM   561  H HE22 . GLN A 1 39  ? 41.54100 -6.28800  21.19100  1.000 25.77709  ? 39  GLN H HE22 1 
ATOM   562  N N    . ALA A 1 40  ? 38.10300 -10.85300 17.47700  1.000 17.32560  ? 40  ALA H N    1 
ATOM   563  C CA   . ALA A 1 40  ? 38.12500 -10.85600 16.02700  1.000 19.13758  ? 40  ALA H CA   1 
ATOM   564  C C    . ALA A 1 40  ? 39.04600 -9.74300  15.53200  1.000 22.03784  ? 40  ALA H C    1 
ATOM   565  O O    . ALA A 1 40  ? 39.21900 -8.72600  16.20800  1.000 20.06722  ? 40  ALA H O    1 
ATOM   566  C CB   . ALA A 1 40  ? 36.71900 -10.66600 15.47000  1.000 19.09720  ? 40  ALA H CB   1 
ATOM   567  H H    . ALA A 1 40  ? 37.35600 -10.60900 17.82500  1.000 20.79430  ? 40  ALA H H    1 
ATOM   568  H HA   . ALA A 1 40  ? 38.45800 -11.70500 15.69700  1.000 22.96867  ? 40  ALA H HA   1 
ATOM   569  H HB1  . ALA A 1 40  ? 36.76700 -10.61300 14.50300  1.000 22.92021  ? 40  ALA H HB1  1 
ATOM   570  H HB2  . ALA A 1 40  ? 36.17100 -11.42300 15.73300  1.000 22.92021  ? 40  ALA H HB2  1 
ATOM   571  H HB3  . ALA A 1 40  ? 36.34500 -9.84600  15.82900  1.000 22.92021  ? 40  ALA H HB3  1 
ATOM   572  N N    . PRO A 1 41  ? 39.65400 -9.91500  14.36100  1.000 22.01750  ? 41  PRO H N    1 
ATOM   573  C CA   . PRO A 1 41  ? 40.59200 -8.89700  13.86700  1.000 24.33798  ? 41  PRO H CA   1 
ATOM   574  C C    . PRO A 1 41  ? 39.98800 -7.50400  13.88400  1.000 22.81703  ? 41  PRO H C    1 
ATOM   575  O O    . PRO A 1 41  ? 38.91900 -7.27300  13.31300  1.000 22.38662  ? 41  PRO H O    1 
ATOM   576  C CB   . PRO A 1 41  ? 40.90000 -9.36600  12.43900  1.000 27.34772  ? 41  PRO H CB   1 
ATOM   577  C CG   . PRO A 1 41  ? 40.64000 -10.82500 12.45400  1.000 28.34889  ? 41  PRO H CG   1 
ATOM   578  C CD   . PRO A 1 41  ? 39.50300 -11.03400 13.41400  1.000 24.73877  ? 41  PRO H CD   1 
ATOM   579  H HA   . PRO A 1 41  ? 41.41000 -8.90200  14.38900  1.000 29.20915  ? 41  PRO H HA   1 
ATOM   580  H HB2  . PRO A 1 41  ? 40.31600 -8.91500  11.81000  1.000 32.82083  ? 41  PRO H HB2  1 
ATOM   581  H HB3  . PRO A 1 41  ? 41.82700 -9.18000  12.22200  1.000 32.82083  ? 41  PRO H HB3  1 
ATOM   582  H HG2  . PRO A 1 41  ? 40.39600 -11.12200 11.56300  1.000 34.02224  ? 41  PRO H HG2  1 
ATOM   583  H HG3  . PRO A 1 41  ? 41.43300 -11.29500 12.75500  1.000 34.02224  ? 41  PRO H HG3  1 
ATOM   584  H HD2  . PRO A 1 41  ? 38.64900 -10.98600 12.95500  1.000 29.69009  ? 41  PRO H HD2  1 
ATOM   585  H HD3  . PRO A 1 41  ? 39.58600 -11.88700 13.86900  1.000 29.69009  ? 41  PRO H HD3  1 
ATOM   586  N N    . GLY A 1 42  ? 40.65200 -6.57800  14.57000  1.000 24.28817  ? 42  GLY H N    1 
ATOM   587  C CA   . GLY A 1 42  ? 40.20300 -5.20600  14.63900  1.000 25.05868  ? 42  GLY H CA   1 
ATOM   588  C C    . GLY A 1 42  ? 39.01800 -4.94100  15.54200  1.000 28.27061  ? 42  GLY H C    1 
ATOM   589  O O    . GLY A 1 42  ? 38.54000 -3.79900  15.57800  1.000 25.19739  ? 42  GLY H O    1 
ATOM   590  H H    . GLY A 1 42  ? 41.37600 -6.72800  15.00800  1.000 29.14937  ? 42  GLY H H    1 
ATOM   591  H HA2  . GLY A 1 42  ? 40.93900 -4.65900  14.95600  1.000 30.07399  ? 42  GLY H HA2  1 
ATOM   592  H HA3  . GLY A 1 42  ? 39.95800 -4.91800  13.74600  1.000 30.07399  ? 42  GLY H HA3  1 
ATOM   593  N N    . LYS A 1 43  ? 38.53100 -5.94200  16.28100  1.000 22.73741  ? 43  LYS H N    1 
ATOM   594  C CA   . LYS A 1 43  ? 37.34000 -5.80700  17.10500  1.000 23.95851  ? 43  LYS H CA   1 
ATOM   595  C C    . LYS A 1 43  ? 37.70300 -5.89400  18.59100  1.000 21.77789  ? 43  LYS H C    1 
ATOM   596  O O    . LYS A 1 43  ? 38.87800 -5.87300  18.97500  1.000 22.06779  ? 43  LYS H O    1 
ATOM   597  C CB   . LYS A 1 43  ? 36.31000 -6.87600  16.72800  1.000 25.56973  ? 43  LYS H CB   1 
ATOM   598  C CG   . LYS A 1 43  ? 36.13200 -7.10500  15.24000  1.000 28.58033  ? 43  LYS H CG   1 
ATOM   599  C CD   . LYS A 1 43  ? 35.72500 -5.84500  14.49500  1.000 27.23740  ? 43  LYS H CD   1 
ATOM   600  C CE   . LYS A 1 43  ? 35.49100 -6.14700  13.01700  1.000 33.17889  ? 43  LYS H CE   1 
ATOM   601  N NZ   . LYS A 1 43  ? 35.34900 -4.91700  12.18500  1.000 34.10830  ? 43  LYS H NZ   1 
ATOM   602  H H    . LYS A 1 43  ? 38.88600 -6.72400  16.31800  1.000 27.28846  ? 43  LYS H H    1 
ATOM   603  H HA   . LYS A 1 43  ? 36.96100 -4.93100  16.93300  1.000 28.75379  ? 43  LYS H HA   1 
ATOM   604  H HB2  . LYS A 1 43  ? 36.58600 -7.71900  17.12100  1.000 30.68724  ? 43  LYS H HB2  1 
ATOM   605  H HB3  . LYS A 1 43  ? 35.44800 -6.61100  17.08600  1.000 30.68724  ? 43  LYS H HB3  1 
ATOM   606  H HG2  . LYS A 1 43  ? 36.97100 -7.41700  14.86500  1.000 34.29996  ? 43  LYS H HG2  1 
ATOM   607  H HG3  . LYS A 1 43  ? 35.44000 -7.77100  15.10200  1.000 34.29996  ? 43  LYS H HG3  1 
ATOM   608  H HD2  . LYS A 1 43  ? 34.90300 -5.49500  14.87300  1.000 32.68845  ? 43  LYS H HD2  1 
ATOM   609  H HD3  . LYS A 1 43  ? 36.43100 -5.18300  14.56700  1.000 32.68845  ? 43  LYS H HD3  1 
ATOM   610  H HE2  . LYS A 1 43  ? 36.24400 -6.65300  12.67500  1.000 39.81824  ? 43  LYS H HE2  1 
ATOM   611  H HE3  . LYS A 1 43  ? 34.67500 -6.66400  12.92700  1.000 39.81824  ? 43  LYS H HE3  1 
ATOM   612  H HZ1  . LYS A 1 43  ? 35.19100 -5.13800  11.33800  1.000 40.93353  ? 43  LYS H HZ1  1 
ATOM   613  H HZ2  . LYS A 1 43  ? 34.67200 -4.42300  12.48500  1.000 40.93353  ? 43  LYS H HZ2  1 
ATOM   614  H HZ3  . LYS A 1 43  ? 36.09700 -4.43500  12.22300  1.000 40.93353  ? 43  LYS H HZ3  1 
ATOM   615  N N    . GLY A 1 44  ? 36.67700 -6.01200  19.43700  1.000 22.55834  ? 44  GLY H N    1 
ATOM   616  C CA   . GLY A 1 44  ? 36.86800 -6.00700  20.87000  1.000 18.65652  ? 44  GLY H CA   1 
ATOM   617  C C    . GLY A 1 44  ? 37.05400 -7.39800  21.44500  1.000 20.47876  ? 44  GLY H C    1 
ATOM   618  O O    . GLY A 1 44  ? 37.03600 -8.40900  20.74600  1.000 19.59746  ? 44  GLY H O    1 
ATOM   619  H H    . GLY A 1 44  ? 35.85700 -6.09700  19.19400  1.000 27.07358  ? 44  GLY H H    1 
ATOM   620  H HA2  . GLY A 1 44  ? 37.65500 -5.48100  21.08500  1.000 22.39139  ? 44  GLY H HA2  1 
ATOM   621  H HA3  . GLY A 1 44  ? 36.09400 -5.60400  21.29300  1.000 22.39139  ? 44  GLY H HA3  1 
ATOM   622  N N    . LEU A 1 45  ? 37.24200 -7.43400  22.76000  1.000 17.90775  ? 45  LEU H N    1 
ATOM   623  C CA   . LEU A 1 45  ? 37.40500 -8.68200  23.48900  1.000 18.31579  ? 45  LEU H CA   1 
ATOM   624  C C    . LEU A 1 45  ? 36.04800 -9.25900  23.86300  1.000 19.91819  ? 45  LEU H C    1 
ATOM   625  O O    . LEU A 1 45  ? 35.14600 -8.53600  24.29400  1.000 21.55828  ? 45  LEU H O    1 
ATOM   626  C CB   . LEU A 1 45  ? 38.23600 -8.45300  24.74800  1.000 19.55938  ? 45  LEU H CB   1 
ATOM   627  C CG   . LEU A 1 45  ? 39.69800 -8.07900  24.51800  1.000 18.82789  ? 45  LEU H CG   1 
ATOM   628  C CD1  . LEU A 1 45  ? 40.29300 -7.48700  25.78600  1.000 18.36794  ? 45  LEU H CD1  1 
ATOM   629  C CD2  . LEU A 1 45  ? 40.48000 -9.30100  24.07700  1.000 20.89878  ? 45  LEU H CD2  1 
ATOM   630  H H    . LEU A 1 45  ? 37.28000 -6.73500  23.26000  1.000 21.49286  ? 45  LEU H H    1 
ATOM   631  H HA   . LEU A 1 45  ? 37.86300 -9.32600  22.92800  1.000 21.98252  ? 45  LEU H HA   1 
ATOM   632  H HB2  . LEU A 1 45  ? 37.83000 -7.73100  25.25300  1.000 23.47483  ? 45  LEU H HB2  1 
ATOM   633  H HB3  . LEU A 1 45  ? 38.22700 -9.27000  25.27100  1.000 23.47483  ? 45  LEU H HB3  1 
ATOM   634  H HG   . LEU A 1 45  ? 39.76000 -7.41000  23.81800  1.000 22.59704  ? 45  LEU H HG   1 
ATOM   635  H HD11 . LEU A 1 45  ? 41.22600 -7.27700  25.62900  1.000 22.04510  ? 45  LEU H HD11 1 
ATOM   636  H HD12 . LEU A 1 45  ? 39.80600 -6.68100  26.01700  1.000 22.04510  ? 45  LEU H HD12 1 
ATOM   637  H HD13 . LEU A 1 45  ? 40.21600 -8.13600  26.50300  1.000 22.04510  ? 45  LEU H HD13 1 
ATOM   638  H HD21 . LEU A 1 45  ? 41.38700 -9.03500  23.86100  1.000 25.08210  ? 45  LEU H HD21 1 
ATOM   639  H HD22 . LEU A 1 45  ? 40.48800 -9.94900  24.79900  1.000 25.08210  ? 45  LEU H HD22 1 
ATOM   640  H HD23 . LEU A 1 45  ? 40.05300 -9.68400  23.29400  1.000 25.08210  ? 45  LEU H HD23 1 
ATOM   641  N N    . GLU A 1 46  ? 35.91800 -10.57500 23.71500  1.000 19.89792  ? 46  GLU H N    1 
ATOM   642  C CA   . GLU A 1 46  ? 34.66800 -11.28100 23.96000  1.000 21.85807  ? 46  GLU H CA   1 
ATOM   643  C C    . GLU A 1 46  ? 34.94800 -12.46700 24.87100  1.000 20.10721  ? 46  GLU H C    1 
ATOM   644  O O    . GLU A 1 46  ? 35.83200 -13.27900 24.58200  1.000 19.97828  ? 46  GLU H O    1 
ATOM   645  C CB   . GLU A 1 46  ? 34.04200 -11.73300 22.63400  1.000 24.04888  ? 46  GLU H CB   1 
ATOM   646  C CG   . GLU A 1 46  ? 32.65200 -12.33200 22.75600  1.000 29.18925  ? 46  GLU H CG   1 
ATOM   647  C CD   . GLU A 1 46  ? 32.02900 -12.64400 21.40200  1.000 34.23954  ? 46  GLU H CD   1 
ATOM   648  O OE1  . GLU A 1 46  ? 32.78400 -12.82500 20.42400  1.000 32.49833  ? 46  GLU H OE1  1 
ATOM   649  O OE2  . GLU A 1 46  ? 30.78400 -12.70400 21.31500  1.000 37.03005  ? 46  GLU H OE2  1 
ATOM   650  H H    . GLU A 1 46  ? 36.55900 -11.09200 23.46700  1.000 23.88107  ? 46  GLU H H    1 
ATOM   651  H HA   . GLU A 1 46  ? 34.03200 -10.70700 24.41400  1.000 26.23326  ? 46  GLU H HA   1 
ATOM   652  H HB2  . GLU A 1 46  ? 33.97700 -10.96400 22.04700  1.000 28.86223  ? 46  GLU H HB2  1 
ATOM   653  H HB3  . GLU A 1 46  ? 34.61500 -12.40700 22.23700  1.000 28.86223  ? 46  GLU H HB3  1 
ATOM   654  H HG2  . GLU A 1 46  ? 32.70600 -13.15900 23.25900  1.000 35.03067  ? 46  GLU H HG2  1 
ATOM   655  H HG3  . GLU A 1 46  ? 32.07500 -11.70200 23.21400  1.000 35.03067  ? 46  GLU H HG3  1 
ATOM   656  N N    . HIS A 1 47  ? 34.22000 -12.54900 25.98200  1.000 20.16704  ? 47  HIS H N    1 
ATOM   657  C CA   . HIS A 1 47  ? 34.39100 -13.65300 26.91600  1.000 20.73735  ? 47  HIS H CA   1 
ATOM   658  C C    . HIS A 1 47  ? 33.57300 -14.84700 26.43800  1.000 20.33607  ? 47  HIS H C    1 
ATOM   659  O O    . HIS A 1 47  ? 32.39300 -14.70500 26.10600  1.000 23.17706  ? 47  HIS H O    1 
ATOM   660  C CB   . HIS A 1 47  ? 33.96500 -13.23700 28.32400  1.000 21.66779  ? 47  HIS H CB   1 
ATOM   661  C CG   . HIS A 1 47  ? 34.30300 -14.24600 29.37600  1.000 22.37780  ? 47  HIS H CG   1 
ATOM   662  N ND1  . HIS A 1 47  ? 33.35300 -15.04300 29.97700  1.000 24.20887  ? 47  HIS H ND1  1 
ATOM   663  C CD2  . HIS A 1 47  ? 35.49000 -14.59500 29.92800  1.000 23.09865  ? 47  HIS H CD2  1 
ATOM   664  C CE1  . HIS A 1 47  ? 33.93900 -15.83700 30.85500  1.000 22.78763  ? 47  HIS H CE1  1 
ATOM   665  N NE2  . HIS A 1 47  ? 35.23500 -15.58300 30.84600  1.000 23.38845  ? 47  HIS H NE2  1 
ATOM   666  H H    . HIS A 1 47  ? 33.62200 -11.97700 26.21600  1.000 24.20402  ? 47  HIS H H    1 
ATOM   667  H HA   . HIS A 1 47  ? 35.32500 -13.91100 26.95600  1.000 24.88839  ? 47  HIS H HA   1 
ATOM   668  H HB2  . HIS A 1 47  ? 34.41400 -12.40800 28.55400  1.000 26.00491  ? 47  HIS H HB2  1 
ATOM   669  H HB3  . HIS A 1 47  ? 33.00400 -13.10900 28.33400  1.000 26.00491  ? 47  HIS H HB3  1 
ATOM   670  H HD1  . HIS A 1 47  ? 32.51000 -15.02600 29.80700  1.000 29.05422  ? 47  HIS H HD1  1 
ATOM   671  H HD2  . HIS A 1 47  ? 36.32100 -14.23200 29.72300  1.000 27.72195  ? 47  HIS H HD2  1 
ATOM   672  H HE1  . HIS A 1 47  ? 33.51100 -16.46700 31.38900  1.000 27.34873  ? 47  HIS H HE1  1 
ATOM   673  N N    . ILE A 1 48  ? 34.20600 -16.02100 26.39400  1.000 20.92690  ? 48  ILE H N    1 
ATOM   674  C CA   . ILE A 1 48  ? 33.56300 -17.23700 25.90700  1.000 20.96638  ? 48  ILE H CA   1 
ATOM   675  C C    . ILE A 1 48  ? 32.98900 -18.03900 27.06900  1.000 25.42889  ? 48  ILE H C    1 
ATOM   676  O O    . ILE A 1 48  ? 31.78600 -18.31800 27.11600  1.000 24.50686  ? 48  ILE H O    1 
ATOM   677  C CB   . ILE A 1 48  ? 34.55800 -18.09400 25.09800  1.000 22.74809  ? 48  ILE H CB   1 
ATOM   678  C CG1  . ILE A 1 48  ? 35.04500 -17.32100 23.86900  1.000 22.59891  ? 48  ILE H CG1  1 
ATOM   679  C CG2  . ILE A 1 48  ? 33.91900 -19.42100 24.70100  1.000 24.32816  ? 48  ILE H CG2  1 
ATOM   680  C CD1  . ILE A 1 48  ? 36.14400 -18.03000 23.07600  1.000 21.15762  ? 48  ILE H CD1  1 
ATOM   681  H H    . ILE A 1 48  ? 35.02000 -16.13800 26.64600  1.000 25.11585  ? 48  ILE H H    1 
ATOM   682  H HA   . ILE A 1 48  ? 32.82300 -16.98000 25.33500  1.000 25.16323  ? 48  ILE H HA   1 
ATOM   683  H HB   . ILE A 1 48  ? 35.32700 -18.28900 25.65700  1.000 27.30128  ? 48  ILE H HB   1 
ATOM   684  H HG12 . ILE A 1 48  ? 34.29400 -17.18400 23.27100  1.000 27.12226  ? 48  ILE H HG12 1 
ATOM   685  H HG13 . ILE A 1 48  ? 35.39900 -16.46600 24.16000  1.000 27.12226  ? 48  ILE H HG13 1 
ATOM   686  H HG21 . ILE A 1 48  ? 34.52900 -19.90300 24.12100  1.000 29.19737  ? 48  ILE H HG21 1 
ATOM   687  H HG22 . ILE A 1 48  ? 33.74300 -19.93900 25.50100  1.000 29.19737  ? 48  ILE H HG22 1 
ATOM   688  H HG23 . ILE A 1 48  ? 33.08900 -19.24300 24.23200  1.000 29.19737  ? 48  ILE H HG23 1 
ATOM   689  H HD11 . ILE A 1 48  ? 36.45100 -17.44400 22.36700  1.000 25.39271  ? 48  ILE H HD11 1 
ATOM   690  H HD12 . ILE A 1 48  ? 36.87900 -18.24000 23.67400  1.000 25.39271  ? 48  ILE H HD12 1 
ATOM   691  H HD13 . ILE A 1 48  ? 35.78300 -18.84700 22.69700  1.000 25.39271  ? 48  ILE H HD13 1 
ATOM   692  N N    . GLY A 1 49  ? 33.85100 -18.44100 27.99800  1.000 22.10674  ? 49  GLY H N    1 
ATOM   693  C CA   . GLY A 1 49  ? 33.41600 -19.23000 29.13500  1.000 26.53897  ? 49  GLY H CA   1 
ATOM   694  C C    . GLY A 1 49  ? 34.47900 -19.24100 30.21000  1.000 22.42523  ? 49  GLY H C    1 
ATOM   695  O O    . GLY A 1 49  ? 35.62200 -18.83600 29.99200  1.000 24.27818  ? 49  GLY H O    1 
ATOM   696  H H    . GLY A 1 49  ? 34.69300 -18.26800 27.98900  1.000 26.53166  ? 49  GLY H H    1 
ATOM   697  H HA2  . GLY A 1 49  ? 32.60200 -18.85400 29.50400  1.000 31.85033  ? 49  GLY H HA2  1 
ATOM   698  H HA3  . GLY A 1 49  ? 33.24400 -20.14300 28.85600  1.000 31.85033  ? 49  GLY H HA3  1 
ATOM   699  N N    . TYR A 1 50  ? 34.07900 -19.72000 31.38500  1.000 28.39995  ? 50  TYR H N    1 
ATOM   700  C CA   . TYR A 1 50  ? 34.91200 -19.71700 32.58200  1.000 26.05789  ? 50  TYR H CA   1 
ATOM   701  C C    . TYR A 1 50  ? 34.85700 -21.09900 33.20800  1.000 27.01777  ? 50  TYR H C    1 
ATOM   702  O O    . TYR A 1 50  ? 33.77600 -21.68400 33.32700  1.000 30.16932  ? 50  TYR H O    1 
ATOM   703  C CB   . TYR A 1 50  ? 34.42300 -18.65100 33.57100  1.000 26.39841  ? 50  TYR H CB   1 
ATOM   704  C CG   . TYR A 1 50  ? 35.22800 -18.49700 34.84500  1.000 25.62764  ? 50  TYR H CG   1 
ATOM   705  C CD1  . TYR A 1 50  ? 36.57600 -18.16900 34.81300  1.000 24.21577  ? 50  TYR H CD1  1 
ATOM   706  C CD2  . TYR A 1 50  ? 34.62100 -18.63600 36.08700  1.000 28.86870  ? 50  TYR H CD2  1 
ATOM   707  C CE1  . TYR A 1 50  ? 37.30200 -18.00700 35.98600  1.000 26.99833  ? 50  TYR H CE1  1 
ATOM   708  C CE2  . TYR A 1 50  ? 35.33500 -18.47700 37.26000  1.000 29.39765  ? 50  TYR H CE2  1 
ATOM   709  C CZ   . TYR A 1 50  ? 36.67300 -18.16400 37.20900  1.000 29.65855  ? 50  TYR H CZ   1 
ATOM   710  O OH   . TYR A 1 50  ? 37.37000 -18.00600 38.39200  1.000 26.41642  ? 50  TYR H OH   1 
ATOM   711  H H    . TYR A 1 50  ? 33.30100 -20.06400 31.51800  1.000 34.08351  ? 50  TYR H H    1 
ATOM   712  H HA   . TYR A 1 50  ? 35.83500 -19.52300 32.35700  1.000 31.27304  ? 50  TYR H HA   1 
ATOM   713  H HB2  . TYR A 1 50  ? 34.43600 -17.79200 33.12000  1.000 31.68166  ? 50  TYR H HB2  1 
ATOM   714  H HB3  . TYR A 1 50  ? 33.51600 -18.87400 33.83200  1.000 31.68166  ? 50  TYR H HB3  1 
ATOM   715  H HD1  . TYR A 1 50  ? 36.99900 -18.05500 33.99200  1.000 29.06249  ? 50  TYR H HD1  1 
ATOM   716  H HD2  . TYR A 1 50  ? 33.71500 -18.84100 36.13000  1.000 34.64601  ? 50  TYR H HD2  1 
ATOM   717  H HE1  . TYR A 1 50  ? 38.20700 -17.79500 35.95000  1.000 32.40157  ? 50  TYR H HE1  1 
ATOM   718  H HE2  . TYR A 1 50  ? 34.91100 -18.58200 38.08100  1.000 35.28075  ? 50  TYR H HE2  1 
ATOM   719  H HH   . TYR A 1 50  ? 38.04300 -17.52000 38.26600  1.000 31.70328  ? 50  TYR H HH   1 
ATOM   720  N N    . LEU A 1 51  ? 36.01700 -21.62300 33.59100  1.000 24.80590  ? 51  LEU H N    1 
ATOM   721  C CA   . LEU A 1 51  ? 36.12300 -22.90900 34.27200  1.000 31.41935  ? 51  LEU H CA   1 
ATOM   722  C C    . LEU A 1 51  ? 36.64200 -22.64100 35.67800  1.000 28.60660  ? 51  LEU H C    1 
ATOM   723  O O    . LEU A 1 51  ? 37.82900 -22.35300 35.85900  1.000 28.70732  ? 51  LEU H O    1 
ATOM   724  C CB   . LEU A 1 51  ? 37.04800 -23.85900 33.51800  1.000 28.89703  ? 51  LEU H CB   1 
ATOM   725  C CG   . LEU A 1 51  ? 37.12200 -25.28300 34.07000  1.000 30.09792  ? 51  LEU H CG   1 
ATOM   726  C CD1  . LEU A 1 51  ? 35.81700 -26.01800 33.82400  1.000 29.38729  ? 51  LEU H CD1  1 
ATOM   727  C CD2  . LEU A 1 51  ? 38.29000 -26.02900 33.45500  1.000 32.20903  ? 51  LEU H CD2  1 
ATOM   728  H H    . LEU A 1 51  ? 36.77700 -21.24200 33.46300  1.000 29.77066  ? 51  LEU H H    1 
ATOM   729  H HA   . LEU A 1 51  ? 35.24800 -23.32400 34.32700  1.000 37.70679  ? 51  LEU H HA   1 
ATOM   730  H HB2  . LEU A 1 51  ? 36.74000 -23.91900 32.60000  1.000 34.68001  ? 51  LEU H HB2  1 
ATOM   731  H HB3  . LEU A 1 51  ? 37.94600 -23.49200 33.54300  1.000 34.68001  ? 51  LEU H HB3  1 
ATOM   732  H HG   . LEU A 1 51  ? 37.26300 -25.24700 35.02900  1.000 36.12108  ? 51  LEU H HG   1 
ATOM   733  H HD11 . LEU A 1 51  ? 35.89500 -26.92300 34.16300  1.000 35.26832  ? 51  LEU H HD11 1 
ATOM   734  H HD12 . LEU A 1 51  ? 35.10000 -25.55200 34.28300  1.000 35.26832  ? 51  LEU H HD12 1 
ATOM   735  H HD13 . LEU A 1 51  ? 35.64000 -26.03600 32.87000  1.000 35.26832  ? 51  LEU H HD13 1 
ATOM   736  H HD21 . LEU A 1 51  ? 38.29900 -26.93800 33.79400  1.000 38.65440  ? 51  LEU H HD21 1 
ATOM   737  H HD22 . LEU A 1 51  ? 38.18700 -26.03700 32.49000  1.000 38.65440  ? 51  LEU H HD22 1 
ATOM   738  H HD23 . LEU A 1 51  ? 39.11500 -25.57800 33.69500  1.000 38.65440  ? 51  LEU H HD23 1 
ATOM   739  N N    . THR A 1 52  ? 35.75600 -22.73600 36.66900  1.000 32.11825  ? 52  THR H N    1 
ATOM   740  C CA   . THR A 1 52  ? 36.12200 -22.39100 38.03300  1.000 32.93697  ? 52  THR H CA   1 
ATOM   741  C C    . THR A 1 52  ? 37.27600 -23.26800 38.51800  1.000 33.09760  ? 52  THR H C    1 
ATOM   742  O O    . THR A 1 52  ? 37.61000 -24.29500 37.92400  1.000 30.94595  ? 52  THR H O    1 
ATOM   743  C CB   . THR A 1 52  ? 34.92700 -22.55600 38.97400  1.000 36.36912  ? 52  THR H CB   1 
ATOM   744  O OG1  . THR A 1 52  ? 34.54900 -23.93800 39.02800  1.000 34.63702  ? 52  THR H OG1  1 
ATOM   745  C CG2  . THR A 1 52  ? 33.74100 -21.72500 38.49800  1.000 32.53758  ? 52  THR H CG2  1 
ATOM   746  H H    . THR A 1 52  ? 34.94200 -22.99800 36.57400  1.000 38.54547  ? 52  THR H H    1 
ATOM   747  H HA   . THR A 1 52  ? 36.40400 -21.46300 38.05200  1.000 39.52794  ? 52  THR H HA   1 
ATOM   748  H HB   . THR A 1 52  ? 35.17200 -22.24900 39.86100  1.000 43.64652  ? 52  THR H HB   1 
ATOM   749  H HG1  . THR A 1 52  ? 33.91400 -24.04200 39.56800  1.000 41.56800  ? 52  THR H HG1  1 
ATOM   750  H HG21 . THR A 1 52  ? 33.00300 -21.81200 39.12100  1.000 39.04867  ? 52  THR H HG21 1 
ATOM   751  H HG22 . THR A 1 52  ? 33.99300 -20.79000 38.43800  1.000 39.04867  ? 52  THR H HG22 1 
ATOM   752  H HG23 . THR A 1 52  ? 33.45200 -22.03000 37.62300  1.000 39.04867  ? 52  THR H HG23 1 
ATOM   753  N N    . ALA A 1 53  ? 37.88300 -22.85200 39.63200  1.000 35.86949  ? 53  ALA H N    1 
ATOM   754  C CA   . ALA A 1 53  ? 38.90600 -23.68600 40.25300  1.000 37.32922  ? 53  ALA H CA   1 
ATOM   755  C C    . ALA A 1 53  ? 38.34200 -25.04700 40.64100  1.000 35.24661  ? 53  ALA H C    1 
ATOM   756  O O    . ALA A 1 53  ? 39.07800 -26.04200 40.66200  1.000 36.40651  ? 53  ALA H O    1 
ATOM   757  C CB   . ALA A 1 53  ? 39.49400 -22.97900 41.47400  1.000 36.63907  ? 53  ALA H CB   1 
ATOM   758  H H    . ALA A 1 53  ? 37.72400 -22.11000 40.03600  1.000 43.04695  ? 53  ALA H H    1 
ATOM   759  H HA   . ALA A 1 53  ? 39.62800 -23.82600 39.62100  1.000 44.79864  ? 53  ALA H HA   1 
ATOM   760  H HB1  . ALA A 1 53  ? 40.17100 -23.54800 41.87300  1.000 43.97046  ? 53  ALA H HB1  1 
ATOM   761  H HB2  . ALA A 1 53  ? 39.89100 -22.14000 41.19300  1.000 43.97046  ? 53  ALA H HB2  1 
ATOM   762  H HB3  . ALA A 1 53  ? 38.78500 -22.81100 42.11400  1.000 43.97046  ? 53  ALA H HB3  1 
ATOM   763  N N    . GLY A 1 54  ? 37.04400 -25.11700 40.93200  1.000 35.38816  ? 54  GLY H N    1 
ATOM   764  C CA   . GLY A 1 54  ? 36.38700 -26.36300 41.25700  1.000 37.30895  ? 54  GLY H CA   1 
ATOM   765  C C    . GLY A 1 54  ? 36.04000 -27.23700 40.07900  1.000 37.75955  ? 54  GLY H C    1 
ATOM   766  O O    . GLY A 1 54  ? 35.55300 -28.35600 40.26600  1.000 33.65732  ? 54  GLY H O    1 
ATOM   767  H H    . GLY A 1 54  ? 36.51800 -24.43700 40.94700  1.000 42.46936  ? 54  GLY H H    1 
ATOM   768  H HA2  . GLY A 1 54  ? 36.96700 -26.87500 41.84200  1.000 44.77431  ? 54  GLY H HA2  1 
ATOM   769  H HA3  . GLY A 1 54  ? 35.56200 -26.16300 41.72700  1.000 44.77431  ? 54  GLY H HA3  1 
ATOM   770  N N    . GLY A 1 55  ? 36.26800 -26.75800 38.85900  1.000 33.26740  ? 55  GLY H N    1 
ATOM   771  C CA   . GLY A 1 55  ? 36.04800 -27.55800 37.67700  1.000 33.12766  ? 55  GLY H CA   1 
ATOM   772  C C    . GLY A 1 55  ? 34.68900 -27.41300 37.03500  1.000 32.48882  ? 55  GLY H C    1 
ATOM   773  O O    . GLY A 1 55  ? 34.34400 -28.22800 36.17100  1.000 30.64795  ? 55  GLY H O    1 
ATOM   774  H H    . GLY A 1 55  ? 36.55400 -25.96400 38.69600  1.000 39.92445  ? 55  GLY H H    1 
ATOM   775  H HA2  . GLY A 1 55  ? 36.71300 -27.31600 37.01400  1.000 39.75676  ? 55  GLY H HA2  1 
ATOM   776  H HA3  . GLY A 1 55  ? 36.16200 -28.49200 37.91200  1.000 39.75676  ? 55  GLY H HA3  1 
ATOM   777  N N    . ARG A 1 56  ? 33.90600 -26.41000 37.42200  1.000 31.89696  ? 56  ARG H N    1 
ATOM   778  C CA   . ARG A 1 56  ? 32.61100 -26.16800 36.80300  1.000 35.19834  ? 56  ARG H CA   1 
ATOM   779  C C    . ARG A 1 56  ? 32.74700 -25.13400 35.69300  1.000 33.50818  ? 56  ARG H C    1 
ATOM   780  O O    . ARG A 1 56  ? 33.42800 -24.11700 35.85300  1.000 32.67799  ? 56  ARG H O    1 
ATOM   781  C CB   . ARG A 1 56  ? 31.58700 -25.69400 37.83500  1.000 36.49827  ? 56  ARG H CB   1 
ATOM   782  C CG   . ARG A 1 56  ? 31.02000 -26.81300 38.69600  1.000 44.32877  ? 56  ARG H CG   1 
ATOM   783  C CD   . ARG A 1 56  ? 29.75900 -26.37500 39.42700  1.000 43.03823  ? 56  ARG H CD   1 
ATOM   784  N NE   . ARG A 1 56  ? 30.03900 -25.44200 40.51200  1.000 41.14811  ? 56  ARG H NE   1 
ATOM   785  C CZ   . ARG A 1 56  ? 29.10800 -24.84100 41.24000  1.000 43.01854  ? 56  ARG H CZ   1 
ATOM   786  N NH1  . ARG A 1 56  ? 27.82000 -25.02500 41.00300  1.000 40.11861  ? 56  ARG H NH1  1 
ATOM   787  N NH2  . ARG A 1 56  ? 29.47900 -24.03600 42.23200  1.000 44.63833  ? 56  ARG H NH2  1 
ATOM   788  H H    . ARG A 1 56  ? 34.10500 -25.85400 38.04700  1.000 38.27993  ? 56  ARG H H    1 
ATOM   789  H HA   . ARG A 1 56  ? 32.28300 -26.99600 36.41700  1.000 42.24158  ? 56  ARG H HA   1 
ATOM   790  H HB2  . ARG A 1 56  ? 32.01400 -25.05400 38.42500  1.000 43.80149  ? 56  ARG H HB2  1 
ATOM   791  H HB3  . ARG A 1 56  ? 30.84700 -25.27400 37.36900  1.000 43.80149  ? 56  ARG H HB3  1 
ATOM   792  H HG2  . ARG A 1 56  ? 30.79600 -27.57000 38.13200  1.000 53.19809  ? 56  ARG H HG2  1 
ATOM   793  H HG3  . ARG A 1 56  ? 31.67900 -27.07500 39.35700  1.000 53.19809  ? 56  ARG H HG3  1 
ATOM   794  H HD2  . ARG A 1 56  ? 29.16500 -25.93500 38.79900  1.000 51.64944  ? 56  ARG H HD2  1 
ATOM   795  H HD3  . ARG A 1 56  ? 29.32500 -27.15500 39.80500  1.000 51.64944  ? 56  ARG H HD3  1 
ATOM   796  H HE   . ARG A 1 56  ? 30.86300 -25.27000 40.69200  1.000 49.38130  ? 56  ARG H HE   1 
ATOM   797  H HH11 . ARG A 1 56  ? 27.57000 -25.54400 40.36400  1.000 48.14590  ? 56  ARG H HH11 1 
ATOM   798  H HH12 . ARG A 1 56  ? 27.23200 -24.62600 41.48700  1.000 48.14590  ? 56  ARG H HH12 1 
ATOM   799  H HH21 . ARG A 1 56  ? 30.31400 -23.91100 42.39500  1.000 53.56957  ? 56  ARG H HH21 1 
ATOM   800  H HH22 . ARG A 1 56  ? 28.88300 -23.64200 42.71100  1.000 53.56957  ? 56  ARG H HH22 1 
ATOM   801  N N    . ALA A 1 57  ? 32.08500 -25.39800 34.57100  1.000 30.61704  ? 57  ALA H N    1 
ATOM   802  C CA   . ALA A 1 57  ? 32.16200 -24.55200 33.39000  1.000 32.20898  ? 57  ALA H CA   1 
ATOM   803  C C    . ALA A 1 57  ? 30.87500 -23.75500 33.24000  1.000 32.22898  ? 57  ALA H C    1 
ATOM   804  O O    . ALA A 1 57  ? 29.77800 -24.32300 33.30000  1.000 30.48697  ? 57  ALA H O    1 
ATOM   805  C CB   . ALA A 1 57  ? 32.40800 -25.39200 32.13400  1.000 33.49876  ? 57  ALA H CB   1 
ATOM   806  H H    . ALA A 1 57  ? 31.57200 -26.08100 34.46900  1.000 36.74402  ? 57  ALA H H    1 
ATOM   807  H HA   . ALA A 1 57  ? 32.89500 -23.92500 33.49300  1.000 38.65435  ? 57  ALA H HA   1 
ATOM   808  H HB1  . ALA A 1 57  ? 32.45400 -24.80300 31.36400  1.000 40.20208  ? 57  ALA H HB1  1 
ATOM   809  H HB2  . ALA A 1 57  ? 33.24600 -25.87100 32.23300  1.000 40.20208  ? 57  ALA H HB2  1 
ATOM   810  H HB3  . ALA A 1 57  ? 31.67800 -26.02100 32.02600  1.000 40.20208  ? 57  ALA H HB3  1 
ATOM   811  N N    . PHE A 1 58  ? 31.01500 -22.44500 33.04500  1.000 30.26750  ? 58  PHE H N    1 
ATOM   812  C CA   . PHE A 1 58  ? 29.89600 -21.55500 32.76000  1.000 31.26807  ? 58  PHE H CA   1 
ATOM   813  C C    . PHE A 1 58  ? 30.20600 -20.78900 31.48500  1.000 29.59706  ? 58  PHE H C    1 
ATOM   814  O O    . PHE A 1 58  ? 31.31300 -20.26400 31.32900  1.000 26.81609  ? 58  PHE H O    1 
ATOM   815  C CB   . PHE A 1 58  ? 29.65000 -20.58700 33.91600  1.000 32.93896  ? 58  PHE H CB   1 
ATOM   816  C CG   . PHE A 1 58  ? 29.37200 -21.26800 35.22500  1.000 31.49737  ? 58  PHE H CG   1 
ATOM   817  C CD1  . PHE A 1 58  ? 28.08200 -21.62500 35.57300  1.000 32.50770  ? 58  PHE H CD1  1 
ATOM   818  C CD2  . PHE A 1 58  ? 30.40200 -21.55100 36.10600  1.000 32.86847  ? 58  PHE H CD2  1 
ATOM   819  C CE1  . PHE A 1 58  ? 27.82400 -22.25100 36.77600  1.000 33.62811  ? 58  PHE H CE1  1 
ATOM   820  C CE2  . PHE A 1 58  ? 30.14900 -22.17600 37.31000  1.000 33.07779  ? 58  PHE H CE2  1 
ATOM   821  C CZ   . PHE A 1 58  ? 28.86000 -22.52600 37.64400  1.000 34.86714  ? 58  PHE H CZ   1 
ATOM   822  H H    . PHE A 1 58  ? 31.77200 -22.03800 33.07300  1.000 36.32457  ? 58  PHE H H    1 
ATOM   823  H HA   . PHE A 1 58  ? 29.08700 -22.07300 32.62600  1.000 37.52525  ? 58  PHE H HA   1 
ATOM   824  H HB2  . PHE A 1 58  ? 30.43700 -20.03200 34.03200  1.000 39.53032  ? 58  PHE H HB2  1 
ATOM   825  H HB3  . PHE A 1 58  ? 28.88200 -20.03400 33.70100  1.000 39.53032  ? 58  PHE H HB3  1 
ATOM   826  H HD1  . PHE A 1 58  ? 27.38100 -21.44100 34.99100  1.000 39.01281  ? 58  PHE H HD1  1 
ATOM   827  H HD2  . PHE A 1 58  ? 31.27400 -21.31800 35.88300  1.000 39.44574  ? 58  PHE H HD2  1 
ATOM   828  H HE1  . PHE A 1 58  ? 26.95300 -22.48800 37.00000  1.000 40.35731  ? 58  PHE H HE1  1 
ATOM   829  H HE2  . PHE A 1 58  ? 30.84900 -22.36000 37.89500  1.000 39.69692  ? 58  PHE H HE2  1 
ATOM   830  H HZ   . PHE A 1 58  ? 28.68700 -22.94700 38.45600  1.000 41.84414  ? 58  PHE H HZ   1 
ATOM   831  N N    . TYR A 1 59  ? 29.23000 -20.71500 30.58400  1.000 29.71700  ? 59  TYR H N    1 
ATOM   832  C CA   . TYR A 1 59  ? 29.42900 -20.16600 29.25200  1.000 32.28843  ? 59  TYR H CA   1 
ATOM   833  C C    . TYR A 1 59  ? 28.56100 -18.93600 29.04500  1.000 33.86865  ? 59  TYR H C    1 
ATOM   834  O O    . TYR A 1 59  ? 27.41700 -18.88900 29.50700  1.000 35.13859  ? 59  TYR H O    1 
ATOM   835  C CB   . TYR A 1 59  ? 29.08700 -21.20300 28.17400  1.000 33.05762  ? 59  TYR H CB   1 
ATOM   836  C CG   . TYR A 1 59  ? 29.78600 -22.53000 28.34800  1.000 34.95781  ? 59  TYR H CG   1 
ATOM   837  C CD1  . TYR A 1 59  ? 31.05600 -22.73600 27.83000  1.000 32.14713  ? 59  TYR H CD1  1 
ATOM   838  C CD2  . TYR A 1 59  ? 29.17500 -23.57700 29.02700  1.000 34.50806  ? 59  TYR H CD2  1 
ATOM   839  C CE1  . TYR A 1 59  ? 31.70100 -23.94000 27.98400  1.000 32.99794  ? 59  TYR H CE1  1 
ATOM   840  C CE2  . TYR A 1 59  ? 29.81500 -24.79000 29.18600  1.000 34.30778  ? 59  TYR H CE2  1 
ATOM   841  C CZ   . TYR A 1 59  ? 31.07800 -24.96400 28.66300  1.000 33.73776  ? 59  TYR H CZ   1 
ATOM   842  O OH   . TYR A 1 59  ? 31.72800 -26.16400 28.81100  1.000 32.93799  ? 59  TYR H OH   1 
ATOM   843  H H    . TYR A 1 59  ? 28.42600 -20.98500 30.72700  1.000 35.66397  ? 59  TYR H H    1 
ATOM   844  H HA   . TYR A 1 59  ? 30.35800 -19.90100 29.16100  1.000 38.74969  ? 59  TYR H HA   1 
ATOM   845  H HB2  . TYR A 1 59  ? 28.13200 -21.36900 28.19500  1.000 39.67271  ? 59  TYR H HB2  1 
ATOM   846  H HB3  . TYR A 1 59  ? 29.34300 -20.84700 27.30900  1.000 39.67271  ? 59  TYR H HB3  1 
ATOM   847  H HD1  . TYR A 1 59  ? 31.47800 -22.04700 27.36900  1.000 38.58013  ? 59  TYR H HD1  1 
ATOM   848  H HD2  . TYR A 1 59  ? 28.32300 -23.45900 29.37900  1.000 41.41325  ? 59  TYR H HD2  1 
ATOM   849  H HE1  . TYR A 1 59  ? 32.55300 -24.06200 27.63300  1.000 39.60110  ? 59  TYR H HE1  1 
ATOM   850  H HE2  . TYR A 1 59  ? 29.39700 -25.48400 29.64300  1.000 41.17290  ? 59  TYR H HE2  1 
ATOM   851  H HH   . TYR A 1 59  ? 31.23300 -26.71100 29.21400  1.000 39.52915  ? 59  TYR H HH   1 
ATOM   852  N N    . ALA A 1 60  ? 29.10200 -17.94800 28.33700  1.000 31.40812  ? 60  ALA H N    1 
ATOM   853  C CA   . ALA A 1 60  ? 28.27900 -16.84200 27.87100  1.000 31.04814  ? 60  ALA H CA   1 
ATOM   854  C C    . ALA A 1 60  ? 27.17100 -17.37700 26.97100  1.000 32.15789  ? 60  ALA H C    1 
ATOM   855  O O    . ALA A 1 60  ? 27.33800 -18.38100 26.27200  1.000 30.34727  ? 60  ALA H O    1 
ATOM   856  C CB   . ALA A 1 60  ? 29.12900 -15.81900 27.12100  1.000 30.18794  ? 60  ALA H CB   1 
ATOM   857  H H    . ALA A 1 60  ? 29.93200 -17.89700 28.11700  1.000 37.69331  ? 60  ALA H H    1 
ATOM   858  H HA   . ALA A 1 60  ? 27.87600 -16.38600 28.62500  1.000 37.26134  ? 60  ALA H HA   1 
ATOM   859  H HB1  . ALA A 1 60  ? 28.55900 -15.09300 26.82200  1.000 36.22909  ? 60  ALA H HB1  1 
ATOM   860  H HB2  . ALA A 1 60  ? 29.81300 -15.47800 27.71900  1.000 36.22909  ? 60  ALA H HB2  1 
ATOM   861  H HB3  . ALA A 1 60  ? 29.54300 -16.25100 26.35700  1.000 36.22909  ? 60  ALA H HB3  1 
ATOM   862  N N    . SER A 1 61  ? 26.02500 -16.69200 26.99300  1.000 35.97849  ? 61  SER H N    1 
ATOM   863  C CA   . SER A 1 61  ? 24.84200 -17.19200 26.30000  1.000 34.37750  ? 61  SER H CA   1 
ATOM   864  C C    . SER A 1 61  ? 25.14800 -17.55800 24.85100  1.000 34.85843  ? 61  SER H C    1 
ATOM   865  O O    . SER A 1 61  ? 24.76400 -18.63200 24.37600  1.000 38.12953  ? 61  SER H O    1 
ATOM   866  C CB   . SER A 1 61  ? 23.72500 -16.14800 26.36200  1.000 39.63856  ? 61  SER H CB   1 
ATOM   867  O OG   . SER A 1 61  ? 23.39200 -15.84100 27.70400  1.000 46.65823  ? 61  SER H OG   1 
ATOM   868  H H    . SER A 1 61  ? 25.91000 -15.94300 27.39800  1.000 43.17775  ? 61  SER H H    1 
ATOM   869  H HA   . SER A 1 61  ? 24.53900 -17.99600 26.75000  1.000 41.25657  ? 61  SER H HA   1 
ATOM   870  H HB2  . SER A 1 61  ? 24.02400 -15.33900 25.91900  1.000 47.56984  ? 61  SER H HB2  1 
ATOM   871  H HB3  . SER A 1 61  ? 22.93900 -16.50000 25.91600  1.000 47.56984  ? 61  SER H HB3  1 
ATOM   872  H HG   . SER A 1 61  ? 22.76200 -15.28500 27.72400  1.000 55.99344  ? 61  SER H HG   1 
ATOM   873  N N    . TRP A 1 62  ? 25.84800 -16.67400 24.13400  1.000 32.66785  ? 62  TRP H N    1 
ATOM   874  C CA   . TRP A 1 62  ? 26.06500 -16.89000 22.70700  1.000 31.87881  ? 62  TRP H CA   1 
ATOM   875  C C    . TRP A 1 62  ? 26.89600 -18.13700 22.43500  1.000 31.10845  ? 62  TRP H C    1 
ATOM   876  O O    . TRP A 1 62  ? 26.75000 -18.75900 21.37700  1.000 32.35903  ? 62  TRP H O    1 
ATOM   877  C CB   . TRP A 1 62  ? 26.75500 -15.67300 22.08600  1.000 32.34978  ? 62  TRP H CB   1 
ATOM   878  C CG   . TRP A 1 62  ? 28.13700 -15.43700 22.61700  1.000 28.47725  ? 62  TRP H CG   1 
ATOM   879  C CD1  . TRP A 1 62  ? 28.47900 -14.67400 23.69200  1.000 30.54866  ? 62  TRP H CD1  1 
ATOM   880  C CD2  . TRP A 1 62  ? 29.36200 -15.96900 22.09800  1.000 31.13974  ? 62  TRP H CD2  1 
ATOM   881  N NE1  . TRP A 1 62  ? 29.84000 -14.69700 23.87800  1.000 29.67845  ? 62  TRP H NE1  1 
ATOM   882  C CE2  . TRP A 1 62  ? 30.40600 -15.48500 22.91100  1.000 27.47707  ? 62  TRP H CE2  1 
ATOM   883  C CE3  . TRP A 1 62  ? 29.67800 -16.80900 21.02700  1.000 28.25759  ? 62  TRP H CE3  1 
ATOM   884  C CZ2  . TRP A 1 62  ? 31.74100 -15.81200 22.68600  1.000 27.18814  ? 62  TRP H CZ2  1 
ATOM   885  C CZ3  . TRP A 1 62  ? 31.00400 -17.13200 20.80500  1.000 27.98866  ? 62  TRP H CZ3  1 
ATOM   886  C CH2  . TRP A 1 62  ? 32.01900 -16.63600 21.63200  1.000 25.50695  ? 62  TRP H CH2  1 
ATOM   887  H H    . TRP A 1 62  ? 26.20200 -15.95500 24.44600  1.000 39.20499  ? 62  TRP H H    1 
ATOM   888  H HA   . TRP A 1 62  ? 25.19900 -17.00400 22.28600  1.000 38.25814  ? 62  TRP H HA   1 
ATOM   889  H HB2  . TRP A 1 62  ? 26.82300 -15.80600 21.12800  1.000 38.82331  ? 62  TRP H HB2  1 
ATOM   890  H HB3  . TRP A 1 62  ? 26.22500 -14.88300 22.27400  1.000 38.82331  ? 62  TRP H HB3  1 
ATOM   891  H HD1  . TRP A 1 62  ? 27.87700 -14.20400 24.22300  1.000 36.66197  ? 62  TRP H HD1  1 
ATOM   892  H HE1  . TRP A 1 62  ? 30.26600 -14.28500 24.50000  1.000 35.61771  ? 62  TRP H HE1  1 
ATOM   893  H HE3  . TRP A 1 62  ? 29.00900 -17.14500 20.47400  1.000 33.91268  ? 62  TRP H HE3  1 
ATOM   894  H HZ2  . TRP A 1 62  ? 32.41800 -15.48300 23.23300  1.000 32.62934  ? 62  TRP H HZ2  1 
ATOM   895  H HZ3  . TRP A 1 62  ? 31.22600 -17.68800 20.09300  1.000 33.58996  ? 62  TRP H HZ3  1 
ATOM   896  H HH2  . TRP A 1 62  ? 32.90200 -16.87300 21.46000  1.000 30.61191  ? 62  TRP H HH2  1 
ATOM   897  N N    . ALA A 1 63  ? 27.77000 -18.51200 23.36700  1.000 29.66759  ? 63  ALA H N    1 
ATOM   898  C CA   . ALA A 1 63  ? 28.71000 -19.60200 23.15000  1.000 31.26908  ? 63  ALA H CA   1 
ATOM   899  C C    . ALA A 1 63  ? 28.22100 -20.94500 23.67400  1.000 33.76906  ? 63  ALA H C    1 
ATOM   900  O O    . ALA A 1 63  ? 28.78400 -21.97700 23.29500  1.000 33.00819  ? 63  ALA H O    1 
ATOM   901  C CB   . ALA A 1 63  ? 30.05100 -19.27200 23.81800  1.000 29.61842  ? 63  ALA H CB   1 
ATOM   902  H H    . ALA A 1 63  ? 27.83700 -18.14400 24.14100  1.000 35.60468  ? 63  ALA H H    1 
ATOM   903  H HA   . ALA A 1 63  ? 28.85100 -19.69400 22.19500  1.000 37.52647  ? 63  ALA H HA   1 
ATOM   904  H HB1  . ALA A 1 63  ? 30.66700 -20.00700 23.66800  1.000 35.54567  ? 63  ALA H HB1  1 
ATOM   905  H HB2  . ALA A 1 63  ? 30.40600 -18.45800 23.42800  1.000 35.54567  ? 63  ALA H HB2  1 
ATOM   906  H HB3  . ALA A 1 63  ? 29.90800 -19.14900 24.76900  1.000 35.54567  ? 63  ALA H HB3  1 
ATOM   907  N N    . LYS A 1 64  ? 27.18400 -20.96200 24.51200  1.000 33.34856  ? 64  LYS H N    1 
ATOM   908  C CA   . LYS A 1 64  ? 26.85900 -22.17300 25.25900  1.000 31.92709  ? 64  LYS H CA   1 
ATOM   909  C C    . LYS A 1 64  ? 26.59900 -23.35900 24.33700  1.000 35.72852  ? 64  LYS H C    1 
ATOM   910  O O    . LYS A 1 64  ? 27.06600 -24.47300 24.60300  1.000 35.67813  ? 64  LYS H O    1 
ATOM   911  C CB   . LYS A 1 64  ? 25.65100 -21.91700 26.16000  1.000 34.37844  ? 64  LYS H CB   1 
ATOM   912  C CG   . LYS A 1 64  ? 25.32300 -23.07900 27.08700  1.000 39.56847  ? 64  LYS H CG   1 
ATOM   913  C CD   . LYS A 1 64  ? 24.31300 -22.68300 28.15200  1.000 37.33866  ? 64  LYS H CD   1 
ATOM   914  C CE   . LYS A 1 64  ? 24.13500 -23.79700 29.17400  1.000 47.65855  ? 64  LYS H CE   1 
ATOM   915  N NZ   . LYS A 1 64  ? 23.04700 -23.50700 30.15000  1.000 50.36801  ? 64  LYS H NZ   1 
ATOM   916  H H    . LYS A 1 64  ? 26.66100 -20.29600 24.66300  1.000 40.02184  ? 64  LYS H H    1 
ATOM   917  H HA   . LYS A 1 64  ? 27.61800 -22.40100 25.81900  1.000 38.31607  ? 64  LYS H HA   1 
ATOM   918  H HB2  . LYS A 1 64  ? 25.83100 -21.14000 26.71100  1.000 41.25770  ? 64  LYS H HB2  1 
ATOM   919  H HB3  . LYS A 1 64  ? 24.87400 -21.75500 25.60200  1.000 41.25770  ? 64  LYS H HB3  1 
ATOM   920  H HG2  . LYS A 1 64  ? 24.94700 -23.80700 26.56700  1.000 47.48574  ? 64  LYS H HG2  1 
ATOM   921  H HG3  . LYS A 1 64  ? 26.13400 -23.37200 27.53100  1.000 47.48574  ? 64  LYS H HG3  1 
ATOM   922  H HD2  . LYS A 1 64  ? 24.62500 -21.88900 28.61500  1.000 44.80997  ? 64  LYS H HD2  1 
ATOM   923  H HD3  . LYS A 1 64  ? 23.45500 -22.50800 27.73500  1.000 44.80997  ? 64  LYS H HD3  1 
ATOM   924  H HE2  . LYS A 1 64  ? 23.91200 -24.61900 28.71100  1.000 57.19383  ? 64  LYS H HE2  1 
ATOM   925  H HE3  . LYS A 1 64  ? 24.96100 -23.90800 29.66900  1.000 57.19383  ? 64  LYS H HE3  1 
ATOM   926  H HZ1  . LYS A 1 64  ? 22.99100 -24.16400 30.74700  1.000 60.44518  ? 64  LYS H HZ1  1 
ATOM   927  H HZ2  . LYS A 1 64  ? 23.21500 -22.74400 30.57600  1.000 60.44518  ? 64  LYS H HZ2  1 
ATOM   928  H HZ3  . LYS A 1 64  ? 22.26800 -23.43500 29.72500  1.000 60.44518  ? 64  LYS H HZ3  1 
ATOM   929  N N    . SER A 1 65  ? 25.87100 -23.14400 23.24300  1.000 37.96946  ? 65  SER H N    1 
ATOM   930  C CA   . SER A 1 65  ? 25.41500 -24.25700 22.42000  1.000 36.86851  ? 65  SER H CA   1 
ATOM   931  C C    . SER A 1 65  ? 26.50200 -24.86300 21.53900  1.000 35.96752  ? 65  SER H C    1 
ATOM   932  O O    . SER A 1 65  ? 26.27900 -25.93800 20.97200  1.000 39.66844  ? 65  SER H O    1 
ATOM   933  C CB   . SER A 1 65  ? 24.24900 -23.80600 21.53600  1.000 39.96961  ? 65  SER H CB   1 
ATOM   934  O OG   . SER A 1 65  ? 24.64600 -22.76500 20.66300  1.000 39.23875  ? 65  SER H OG   1 
ATOM   935  H H    . SER A 1 65  ? 25.63200 -22.36900 22.95900  1.000 45.56692  ? 65  SER H H    1 
ATOM   936  H HA   . SER A 1 65  ? 25.10300 -24.95800 23.01400  1.000 44.24578  ? 65  SER H HA   1 
ATOM   937  H HB2  . SER A 1 65  ? 23.94300 -24.56100 21.00900  1.000 47.96710  ? 65  SER H HB2  1 
ATOM   938  H HB3  . SER A 1 65  ? 23.53000 -23.48500 22.10300  1.000 47.96710  ? 65  SER H HB3  1 
ATOM   939  H HG   . SER A 1 65  ? 24.83100 -22.07400 21.10400  1.000 47.09007  ? 65  SER H HG   1 
ATOM   940  N N    . ARG A 1 66  ? 27.66200 -24.21700 21.40400  1.000 37.76767  ? 66  ARG H N    1 
ATOM   941  C CA   . ARG A 1 66  ? 28.72800 -24.72900 20.55600  1.000 37.52820  ? 66  ARG H CA   1 
ATOM   942  C C    . ARG A 1 66  ? 30.04800 -24.94400 21.28000  1.000 35.39839  ? 66  ARG H C    1 
ATOM   943  O O    . ARG A 1 66  ? 30.96800 -25.51500 20.68500  1.000 32.53666  ? 66  ARG H O    1 
ATOM   944  C CB   . ARG A 1 66  ? 28.98500 -23.77900 19.37100  1.000 36.88778  ? 66  ARG H CB   1 
ATOM   945  C CG   . ARG A 1 66  ? 27.84700 -23.68600 18.37300  1.000 38.38764  ? 66  ARG H CG   1 
ATOM   946  C CD   . ARG A 1 66  ? 28.21400 -22.81400 17.15900  1.000 37.43792  ? 66  ARG H CD   1 
ATOM   947  N NE   . ARG A 1 66  ? 28.63400 -21.46800 17.53600  1.000 36.20741  ? 66  ARG H NE   1 
ATOM   948  C CZ   . ARG A 1 66  ? 29.70400 -20.84000 17.05900  1.000 35.49837  ? 66  ARG H CZ   1 
ATOM   949  N NH1  . ARG A 1 66  ? 30.47900 -21.38800 16.13700  1.000 34.34874  ? 66  ARG H NH1  1 
ATOM   950  N NH2  . ARG A 1 66  ? 29.99800 -19.62500 17.51400  1.000 32.87819  ? 66  ARG H NH2  1 
ATOM   951  H H    . ARG A 1 66  ? 27.85200 -23.47600 21.79700  1.000 45.32478  ? 66  ARG H H    1 
ATOM   952  H HA   . ARG A 1 66  ? 28.43700 -25.58400 20.20200  1.000 45.03741  ? 66  ARG H HA   1 
ATOM   953  H HB2  . ARG A 1 66  ? 29.14100 -22.88800 19.72000  1.000 44.26891  ? 66  ARG H HB2  1 
ATOM   954  H HB3  . ARG A 1 66  ? 29.76900 -24.09000 18.89200  1.000 44.26891  ? 66  ARG H HB3  1 
ATOM   955  H HG2  . ARG A 1 66  ? 27.63000 -24.57500 18.05300  1.000 46.06874  ? 66  ARG H HG2  1 
ATOM   956  H HG3  . ARG A 1 66  ? 27.07400 -23.29200 18.80600  1.000 46.06874  ? 66  ARG H HG3  1 
ATOM   957  H HD2  . ARG A 1 66  ? 28.94500 -23.23300 16.67800  1.000 44.92907  ? 66  ARG H HD2  1 
ATOM   958  H HD3  . ARG A 1 66  ? 27.43900 -22.73500 16.58100  1.000 44.92907  ? 66  ARG H HD3  1 
ATOM   959  H HE   . ARG A 1 66  ? 28.15200 -21.04800 18.11200  1.000 43.45246  ? 66  ARG H HE   1 
ATOM   960  H HH11 . ARG A 1 66  ? 30.29600 -22.17000 15.83100  1.000 41.22206  ? 66  ARG H HH11 1 
ATOM   961  H HH12 . ARG A 1 66  ? 31.16600 -20.96100 15.84400  1.000 41.22206  ? 66  ARG H HH12 1 
ATOM   962  H HH21 . ARG A 1 66  ? 29.49800 -19.25600 18.10900  1.000 39.45740  ? 66  ARG H HH21 1 
ATOM   963  H HH22 . ARG A 1 66  ? 30.68700 -19.20800 17.21300  1.000 39.45740  ? 66  ARG H HH22 1 
ATOM   964  N N    . SER A 1 67  ? 30.17200 -24.51600 22.53200  1.000 34.15728  ? 67  SER H N    1 
ATOM   965  C CA   . SER A 1 67  ? 31.45300 -24.48100 23.21900  1.000 35.79838  ? 67  SER H CA   1 
ATOM   966  C C    . SER A 1 67  ? 31.51100 -25.51900 24.33000  1.000 33.82805  ? 67  SER H C    1 
ATOM   967  O O    . SER A 1 67  ? 30.50100 -25.84200 24.95900  1.000 32.39719  ? 67  SER H O    1 
ATOM   968  C CB   . SER A 1 67  ? 31.71300 -23.09200 23.81400  1.000 33.85754  ? 67  SER H CB   1 
ATOM   969  O OG   . SER A 1 67  ? 31.63600 -22.09100 22.81600  1.000 36.23888  ? 67  SER H OG   1 
ATOM   970  H H    . SER A 1 67  ? 29.51500 -24.23700 23.01100  1.000 40.99230  ? 67  SER H H    1 
ATOM   971  H HA   . SER A 1 67  ? 32.15200 -24.69000 22.58100  1.000 42.96163  ? 67  SER H HA   1 
ATOM   972  H HB2  . SER A 1 67  ? 31.04600 -22.91100 24.49500  1.000 40.63262  ? 67  SER H HB2  1 
ATOM   973  H HB3  . SER A 1 67  ? 32.60000 -23.07900 24.20700  1.000 40.63262  ? 67  SER H HB3  1 
ATOM   974  H HG   . SER A 1 67  ? 30.86200 -22.07000 22.49000  1.000 43.49022  ? 67  SER H HG   1 
ATOM   975  N N    . THR A 1 68  ? 32.71800 -26.02500 24.57200  1.000 31.44718  ? 68  THR H N    1 
ATOM   976  C CA   . THR A 1 68  ? 32.97900 -26.93500 25.68000  1.000 31.24801  ? 68  THR H CA   1 
ATOM   977  C C    . THR A 1 68  ? 34.35100 -26.60200 26.24100  1.000 29.37755  ? 68  THR H C    1 
ATOM   978  O O    . THR A 1 68  ? 35.34500 -26.64300 25.50900  1.000 28.43736  ? 68  THR H O    1 
ATOM   979  C CB   . THR A 1 68  ? 32.92600 -28.39900 25.23400  1.000 35.15821  ? 68  THR H CB   1 
ATOM   980  O OG1  . THR A 1 68  ? 31.70400 -28.64600 24.52700  1.000 39.34743  ? 68  THR H OG1  1 
ATOM   981  C CG2  . THR A 1 68  ? 33.01000 -29.33000 26.44100  1.000 31.43852  ? 68  THR H CG2  1 
ATOM   982  H H    . THR A 1 68  ? 33.41400 -25.85200 24.09800  1.000 37.74019  ? 68  THR H H    1 
ATOM   983  H HA   . THR A 1 68  ? 32.31000 -26.80900 26.37100  1.000 37.50119  ? 68  THR H HA   1 
ATOM   984  H HB   . THR A 1 68  ? 33.67800 -28.58600 24.65100  1.000 42.19342  ? 68  THR H HB   1 
ATOM   985  H HG1  . THR A 1 68  ? 31.69100 -29.43700 24.24300  1.000 47.22048  ? 68  THR H HG1  1 
ATOM   986  H HG21 . THR A 1 68  ? 32.98800 -30.25400 26.14900  1.000 37.72979  ? 68  THR H HG21 1 
ATOM   987  H HG22 . THR A 1 68  ? 33.83600 -29.17200 26.92400  1.000 37.72979  ? 68  THR H HG22 1 
ATOM   988  H HG23 . THR A 1 68  ? 32.26100 -29.17000 27.03600  1.000 37.72979  ? 68  THR H HG23 1 
ATOM   989  N N    . ILE A 1 69  ? 34.40600 -26.26100 27.52400  1.000 28.28668  ? 69  ILE H N    1 
ATOM   990  C CA   . ILE A 1 69  ? 35.65600 -25.96500 28.21300  1.000 27.65649  ? 69  ILE H CA   1 
ATOM   991  C C    . ILE A 1 69  ? 35.88900 -27.06400 29.23700  1.000 31.02891  ? 69  ILE H C    1 
ATOM   992  O O    . ILE A 1 69  ? 35.00300 -27.36400 30.04700  1.000 28.28682  ? 69  ILE H O    1 
ATOM   993  C CB   . ILE A 1 69  ? 35.62500 -24.58300 28.88600  1.000 27.58745  ? 69  ILE H CB   1 
ATOM   994  C CG1  . ILE A 1 69  ? 35.39100 -23.48900 27.84200  1.000 30.10853  ? 69  ILE H CG1  1 
ATOM   995  C CG2  . ILE A 1 69  ? 36.93400 -24.32200 29.62100  1.000 25.43675  ? 69  ILE H CG2  1 
ATOM   996  C CD1  . ILE A 1 69  ? 35.02200 -22.14600 28.43600  1.000 28.91837  ? 69  ILE H CD1  1 
ATOM   997  H H    . ILE A 1 69  ? 33.71400 -26.19300 28.02900  1.000 33.94759  ? 69  ILE H H    1 
ATOM   998  H HA   . ILE A 1 69  ? 36.38700 -25.96800 27.57500  1.000 33.19136  ? 69  ILE H HA   1 
ATOM   999  H HB   . ILE A 1 69  ? 34.89500 -24.57200 29.52500  1.000 33.10851  ? 69  ILE H HB   1 
ATOM   1000 H HG12 . ILE A 1 69  ? 36.20400 -23.37100 27.32700  1.000 36.13381  ? 69  ILE H HG12 1 
ATOM   1001 H HG13 . ILE A 1 69  ? 34.66600 -23.76500 27.26000  1.000 36.13381  ? 69  ILE H HG13 1 
ATOM   1002 H HG21 . ILE A 1 69  ? 36.92500 -23.41700 29.96900  1.000 30.52767  ? 69  ILE H HG21 1 
ATOM   1003 H HG22 . ILE A 1 69  ? 37.01800 -24.95600 30.35100  1.000 30.52767  ? 69  ILE H HG22 1 
ATOM   1004 H HG23 . ILE A 1 69  ? 37.67100 -24.43200 29.00100  1.000 30.52767  ? 69  ILE H HG23 1 
ATOM   1005 H HD11 . ILE A 1 69  ? 34.86400 -21.51500 27.71700  1.000 34.70561  ? 69  ILE H HD11 1 
ATOM   1006 H HD12 . ILE A 1 69  ? 34.21800 -22.24700 28.97000  1.000 34.70561  ? 69  ILE H HD12 1 
ATOM   1007 H HD13 . ILE A 1 69  ? 35.75300 -21.83600 28.99400  1.000 34.70561  ? 69  ILE H HD13 1 
ATOM   1008 N N    . THR A 1 70  ? 37.07500 -27.66700 29.19500  1.000 30.37794  ? 70  THR H N    1 
ATOM   1009 C CA   . THR A 1 70  ? 37.42500 -28.76800 30.07600  1.000 32.02865  ? 70  THR H CA   1 
ATOM   1010 C C    . THR A 1 70  ? 38.84400 -28.55200 30.58100  1.000 30.58789  ? 70  THR H C    1 
ATOM   1011 O O    . THR A 1 70  ? 39.51000 -27.57500 30.22800  1.000 28.54636  ? 70  THR H O    1 
ATOM   1012 C CB   . THR A 1 70  ? 37.29700 -30.11800 29.35800  1.000 32.92925  ? 70  THR H CB   1 
ATOM   1013 O OG1  . THR A 1 70  ? 38.16300 -30.14100 28.21500  1.000 30.94765  ? 70  THR H OG1  1 
ATOM   1014 C CG2  . THR A 1 70  ? 35.86300 -30.34800 28.90400  1.000 30.42871  ? 70  THR H CG2  1 
ATOM   1015 H H    . THR A 1 70  ? 37.70500 -27.44800 28.65100  1.000 36.45710  ? 70  THR H H    1 
ATOM   1016 H HA   . THR A 1 70  ? 36.82100 -28.76800 30.83500  1.000 38.43794  ? 70  THR H HA   1 
ATOM   1017 H HB   . THR A 1 70  ? 37.54600 -30.83000 29.96700  1.000 39.51867  ? 70  THR H HB   1 
ATOM   1018 H HG1  . THR A 1 70  ? 38.93300 -30.38900 28.44300  1.000 37.14075  ? 70  THR H HG1  1 
ATOM   1019 H HG21 . THR A 1 70  ? 35.79100 -31.20400 28.45500  1.000 36.51802  ? 70  THR H HG21 1 
ATOM   1020 H HG22 . THR A 1 70  ? 35.26800 -30.34300 29.67000  1.000 36.51802  ? 70  THR H HG22 1 
ATOM   1021 H HG23 . THR A 1 70  ? 35.59300 -29.64700 28.29000  1.000 36.51802  ? 70  THR H HG23 1 
ATOM   1022 N N    . ARG A 1 71  ? 39.30600 -29.46900 31.42400  1.000 30.70784  ? 71  ARG H N    1 
ATOM   1023 C CA   . ARG A 1 71  ? 40.66900 -29.40700 31.92100  1.000 30.13632  ? 71  ARG H CA   1 
ATOM   1024 C C    . ARG A 1 71  ? 41.17000 -30.81800 32.17200  1.000 34.66831  ? 71  ARG H C    1 
ATOM   1025 O O    . ARG A 1 71  ? 40.39600 -31.71900 32.50900  1.000 34.51779  ? 71  ARG H O    1 
ATOM   1026 C CB   . ARG A 1 71  ? 40.77600 -28.58000 33.20600  1.000 33.84774  ? 71  ARG H CB   1 
ATOM   1027 C CG   . ARG A 1 71  ? 40.10100 -29.20100 34.42700  1.000 36.06818  ? 71  ARG H CG   1 
ATOM   1028 C CD   . ARG A 1 71  ? 40.25000 -28.28700 35.63800  1.000 37.13736  ? 71  ARG H CD   1 
ATOM   1029 N NE   . ARG A 1 71  ? 39.68900 -28.86000 36.85600  1.000 40.98787  ? 71  ARG H NE   1 
ATOM   1030 C CZ   . ARG A 1 71  ? 39.58800 -28.21100 38.00900  1.000 43.55833  ? 71  ARG H CZ   1 
ATOM   1031 N NH1  . ARG A 1 71  ? 39.98900 -26.95600 38.13300  1.000 40.22793  ? 71  ARG H NH1  1 
ATOM   1032 N NH2  . ARG A 1 71  ? 39.06400 -28.83500 39.06100  1.000 42.69681  ? 71  ARG H NH2  1 
ATOM   1033 H H    . ARG A 1 71  ? 38.84900 -30.13500 31.72100  1.000 36.85298  ? 71  ARG H H    1 
ATOM   1034 H HA   . ARG A 1 71  ? 41.23300 -28.99300 31.24900  1.000 36.16716  ? 71  ARG H HA   1 
ATOM   1035 H HB2  . ARG A 1 71  ? 41.71500 -28.46300 33.41900  1.000 40.62086  ? 71  ARG H HB2  1 
ATOM   1036 H HB3  . ARG A 1 71  ? 40.36100 -27.71700 33.05100  1.000 40.62086  ? 71  ARG H HB3  1 
ATOM   1037 H HG2  . ARG A 1 71  ? 39.15600 -29.32600 34.24800  1.000 43.28539  ? 71  ARG H HG2  1 
ATOM   1038 H HG3  . ARG A 1 71  ? 40.51700 -30.05300 34.62900  1.000 43.28539  ? 71  ARG H HG3  1 
ATOM   1039 H HD2  . ARG A 1 71  ? 41.19200 -28.12000 35.79300  1.000 44.56840  ? 71  ARG H HD2  1 
ATOM   1040 H HD3  . ARG A 1 71  ? 39.78900 -27.45200 35.46100  1.000 44.56840  ? 71  ARG H HD3  1 
ATOM   1041 H HE   . ARG A 1 71  ? 39.40600 -29.67200 36.82500  1.000 49.18902  ? 71  ARG H HE   1 
ATOM   1042 H HH11 . ARG A 1 71  ? 40.32400 -26.54300 37.45800  1.000 48.27709  ? 71  ARG H HH11 1 
ATOM   1043 H HH12 . ARG A 1 71  ? 39.91400 -26.55400 38.88900  1.000 48.27709  ? 71  ARG H HH12 1 
ATOM   1044 H HH21 . ARG A 1 71  ? 38.79700 -29.64900 38.98900  1.000 51.23975  ? 71  ARG H HH21 1 
ATOM   1045 H HH22 . ARG A 1 71  ? 38.99400 -28.42400 39.81300  1.000 51.23975  ? 71  ARG H HH22 1 
ATOM   1046 N N    . ASN A 1 72  ? 42.47200 -30.99600 32.00000  1.000 34.82770  ? 72  ASN H N    1 
ATOM   1047 C CA   . ASN A 1 72  ? 43.14700 -32.26600 32.24100  1.000 37.10819  ? 72  ASN H CA   1 
ATOM   1048 C C    . ASN A 1 72  ? 44.09600 -32.04100 33.41300  1.000 37.66822  ? 72  ASN H C    1 
ATOM   1049 O O    . ASN A 1 72  ? 45.16300 -31.43900 33.25800  1.000 35.37686  ? 72  ASN H O    1 
ATOM   1050 C CB   . ASN A 1 72  ? 43.87800 -32.74400 30.99300  1.000 35.94736  ? 72  ASN H CB   1 
ATOM   1051 C CG   . ASN A 1 72  ? 44.42100 -34.15000 31.14200  1.000 38.81852  ? 72  ASN H CG   1 
ATOM   1052 O OD1  . ASN A 1 72  ? 44.94000 -34.52000 32.19500  1.000 36.80716  ? 72  ASN H OD1  1 
ATOM   1053 N ND2  . ASN A 1 72  ? 44.30800 -34.94200 30.08400  1.000 39.99771  ? 72  ASN H ND2  1 
ATOM   1054 H H    . ASN A 1 72  ? 43.00500 -30.37500 31.73400  1.000 41.79681  ? 72  ASN H H    1 
ATOM   1055 H HA   . ASN A 1 72  ? 42.50300 -32.95000 32.48200  1.000 44.53340  ? 72  ASN H HA   1 
ATOM   1056 H HB2  . ASN A 1 72  ? 43.26300 -32.73700 30.24300  1.000 43.14040  ? 72  ASN H HB2  1 
ATOM   1057 H HB3  . ASN A 1 72  ? 44.62400 -32.15000 30.81600  1.000 43.14040  ? 72  ASN H HB3  1 
ATOM   1058 H HD21 . ASN A 1 72  ? 44.60100 -35.74900 30.11800  1.000 48.00082  ? 72  ASN H HD21 1 
ATOM   1059 H HD22 . ASN A 1 72  ? 43.94100 -34.64700 29.36400  1.000 48.00082  ? 72  ASN H HD22 1 
ATOM   1060 N N    . THR A 1 73  ? 43.69100 -32.51600 34.59000  1.000 37.04692  ? 73  THR H N    1 
ATOM   1061 C CA   . THR A 1 73  ? 44.48400 -32.29500 35.79200  1.000 37.66819  ? 73  THR H CA   1 
ATOM   1062 C C    . THR A 1 73  ? 45.83000 -33.00300 35.71900  1.000 35.57744  ? 73  THR H C    1 
ATOM   1063 O O    . THR A 1 73  ? 46.82500 -32.48900 36.24100  1.000 36.66866  ? 73  THR H O    1 
ATOM   1064 C CB   . THR A 1 73  ? 43.70200 -32.76900 37.01400  1.000 35.31663  ? 73  THR H CB   1 
ATOM   1065 O OG1  . THR A 1 73  ? 43.47100 -34.17900 36.90900  1.000 32.90689  ? 73  THR H OG1  1 
ATOM   1066 C CG2  . THR A 1 73  ? 42.36500 -32.04300 37.10200  1.000 38.13729  ? 73  THR H CG2  1 
ATOM   1067 H H    . THR A 1 73  ? 42.96800 -32.96500 34.71700  1.000 44.45987  ? 73  THR H H    1 
ATOM   1068 H HA   . THR A 1 73  ? 44.65400 -31.34500 35.88700  1.000 45.20539  ? 73  THR H HA   1 
ATOM   1069 H HB   . THR A 1 73  ? 44.20700 -32.58100 37.82100  1.000 42.38352  ? 73  THR H HB   1 
ATOM   1070 H HG1  . THR A 1 73  ? 42.90200 -34.42000 37.47800  1.000 39.49184  ? 73  THR H HG1  1 
ATOM   1071 H HG21 . THR A 1 73  ? 41.92300 -32.26100 37.93700  1.000 45.76832  ? 73  THR H HG21 1 
ATOM   1072 H HG22 . THR A 1 73  ? 42.50500 -31.08400 37.06200  1.000 45.76832  ? 73  THR H HG22 1 
ATOM   1073 H HG23 . THR A 1 73  ? 41.79400 -32.30900 36.36400  1.000 45.76832  ? 73  THR H HG23 1 
ATOM   1074 N N    . ASN A 1 74  ? 45.88500 -34.17400 35.08300  1.000 33.54691  ? 74  ASN H N    1 
ATOM   1075 C CA   . ASN A 1 74  ? 47.16500 -34.85900 34.93800  1.000 35.84764  ? 74  ASN H CA   1 
ATOM   1076 C C    . ASN A 1 74  ? 48.09700 -34.08900 34.00900  1.000 39.36854  ? 74  ASN H C    1 
ATOM   1077 O O    . ASN A 1 74  ? 49.28700 -33.93000 34.30600  1.000 37.63769  ? 74  ASN H O    1 
ATOM   1078 C CB   . ASN A 1 74  ? 46.94300 -36.27900 34.42300  1.000 34.98849  ? 74  ASN H CB   1 
ATOM   1079 C CG   . ASN A 1 74  ? 46.07300 -37.09800 35.34700  1.000 33.34788  ? 74  ASN H CG   1 
ATOM   1080 O OD1  . ASN A 1 74  ? 46.56600 -37.76100 36.25900  1.000 38.85040  ? 74  ASN H OD1  1 
ATOM   1081 N ND2  . ASN A 1 74  ? 44.76700 -37.05200 35.12100  1.000 34.74771  ? 74  ASN H ND2  1 
ATOM   1082 H H    . ASN A 1 74  ? 45.21300 -34.58300 34.73600  1.000 40.25987  ? 74  ASN H H    1 
ATOM   1083 H HA   . ASN A 1 74  ? 47.59000 -34.92000 35.80700  1.000 43.02073  ? 74  ASN H HA   1 
ATOM   1084 H HB2  . ASN A 1 74  ? 46.50800 -36.23800 33.55700  1.000 41.98976  ? 74  ASN H HB2  1 
ATOM   1085 H HB3  . ASN A 1 74  ? 47.80100 -36.72500 34.34200  1.000 41.98976  ? 74  ASN H HB3  1 
ATOM   1086 H HD21 . ASN A 1 74  ? 44.22800 -37.50000 35.61900  1.000 41.70082  ? 74  ASN H HD21 1 
ATOM   1087 H HD22 . ASN A 1 74  ? 44.45900 -36.57400 34.47600  1.000 41.70082  ? 74  ASN H HD22 1 
ATOM   1088 N N    . GLU A 1 75  ? 47.57100 -33.59700 32.88500  1.000 36.92743  ? 75  GLU H N    1 
ATOM   1089 C CA   . GLU A 1 75  ? 48.38300 -32.85600 31.93000  1.000 39.09806  ? 75  GLU H CA   1 
ATOM   1090 C C    . GLU A 1 75  ? 48.64000 -31.41900 32.36500  1.000 39.21828  ? 75  GLU H C    1 
ATOM   1091 O O    . GLU A 1 75  ? 49.52300 -30.76300 31.80300  1.000 36.27721  ? 75  GLU H O    1 
ATOM   1092 C CB   . GLU A 1 75  ? 47.70400 -32.84200 30.55700  1.000 40.57774  ? 75  GLU H CB   1 
ATOM   1093 C CG   . GLU A 1 75  ? 47.36100 -34.21400 29.99800  1.000 43.54820  ? 75  GLU H CG   1 
ATOM   1094 C CD   . GLU A 1 75  ? 48.54800 -34.90800 29.36600  1.000 52.66802  ? 75  GLU H CD   1 
ATOM   1095 O OE1  . GLU A 1 75  ? 49.67600 -34.75500 29.88100  1.000 55.80815  ? 75  GLU H OE1  1 
ATOM   1096 O OE2  . GLU A 1 75  ? 48.34900 -35.60300 28.34600  1.000 55.56847  ? 75  GLU H OE2  1 
ATOM   1097 H H    . GLU A 1 75  ? 46.74700 -33.68100 32.65500  1.000 44.31649  ? 75  GLU H H    1 
ATOM   1098 H HA   . GLU A 1 75  ? 49.23800 -33.30600 31.84400  1.000 46.92124  ? 75  GLU H HA   1 
ATOM   1099 H HB2  . GLU A 1 75  ? 46.87600 -32.34200 30.62900  1.000 48.69685  ? 75  GLU H HB2  1 
ATOM   1100 H HB3  . GLU A 1 75  ? 48.29900 -32.41000 29.92400  1.000 48.69685  ? 75  GLU H HB3  1 
ATOM   1101 H HG2  . GLU A 1 75  ? 47.03600 -34.77500 30.71900  1.000 52.26141  ? 75  GLU H HG2  1 
ATOM   1102 H HG3  . GLU A 1 75  ? 46.67500 -34.11500 29.31900  1.000 52.26141  ? 75  GLU H HG3  1 
ATOM   1103 N N    . ASN A 1 76  ? 47.88800 -30.91500 33.34200  1.000 37.88849  ? 76  ASN H N    1 
ATOM   1104 C CA   . ASN A 1 76  ? 48.00800 -29.52500 33.77400  1.000 36.76747  ? 76  ASN H CA   1 
ATOM   1105 C C    . ASN A 1 76  ? 47.64100 -28.58000 32.63100  1.000 37.13808  ? 76  ASN H C    1 
ATOM   1106 O O    . ASN A 1 76  ? 48.35600 -27.62200 32.32900  1.000 33.61670  ? 76  ASN H O    1 
ATOM   1107 C CB   . ASN A 1 76  ? 49.41800 -29.23600 34.29600  1.000 36.65788  ? 76  ASN H CB   1 
ATOM   1108 C CG   . ASN A 1 76  ? 49.46400 -28.02700 35.21200  1.000 37.82770  ? 76  ASN H CG   1 
ATOM   1109 O OD1  . ASN A 1 76  ? 48.49800 -27.73100 35.91300  1.000 37.51857  ? 76  ASN H OD1  1 
ATOM   1110 N ND2  . ASN A 1 76  ? 50.58800 -27.32200 35.21000  1.000 35.74808  ? 76  ASN H ND2  1 
ATOM   1111 H H    . ASN A 1 76  ? 47.29400 -31.36300 33.77300  1.000 45.46975  ? 76  ASN H H    1 
ATOM   1112 H HA   . ASN A 1 76  ? 47.38700 -29.36700 34.50300  1.000 44.12454  ? 76  ASN H HA   1 
ATOM   1113 H HB2  . ASN A 1 76  ? 49.73500 -30.00400 34.79600  1.000 43.99303  ? 76  ASN H HB2  1 
ATOM   1114 H HB3  . ASN A 1 76  ? 50.00600 -29.06500 33.54300  1.000 43.99303  ? 76  ASN H HB3  1 
ATOM   1115 H HD21 . ASN A 1 76  ? 50.66200 -26.62800 35.71200  1.000 42.90127  ? 76  ASN H HD21 1 
ATOM   1116 H HD22 . ASN A 1 76  ? 51.24300 -27.55900 34.70600  1.000 42.90127  ? 76  ASN H HD22 1 
ATOM   1117 N N    . THR A 1 77  ? 46.50600 -28.86100 31.99100  1.000 35.53702  ? 77  THR H N    1 
ATOM   1118 C CA   . THR A 1 77  ? 46.05100 -28.10700 30.83400  1.000 36.60868  ? 77  THR H CA   1 
ATOM   1119 C C    . THR A 1 77  ? 44.58400 -27.72800 30.99400  1.000 34.26847  ? 77  THR H C    1 
ATOM   1120 O O    . THR A 1 77  ? 43.83800 -28.34000 31.76300  1.000 32.79746  ? 77  THR H O    1 
ATOM   1121 C CB   . THR A 1 77  ? 46.23300 -28.90600 29.52400  1.000 34.73790  ? 77  THR H CB   1 
ATOM   1122 O OG1  . THR A 1 77  ? 45.50100 -30.13800 29.59000  1.000 31.33659  ? 77  THR H OG1  1 
ATOM   1123 C CG2  . THR A 1 77  ? 47.70200 -29.21400 29.27300  1.000 36.80904  ? 77  THR H CG2  1 
ATOM   1124 H H    . THR A 1 77  ? 45.97400 -29.49900 32.21600  1.000 42.64799  ? 77  THR H H    1 
ATOM   1125 H HA   . THR A 1 77  ? 46.57100 -27.29000 30.77500  1.000 43.93399  ? 77  THR H HA   1 
ATOM   1126 H HB   . THR A 1 77  ? 45.90000 -28.37100 28.78600  1.000 41.68905  ? 77  THR H HB   1 
ATOM   1127 H HG1  . THR A 1 77  ? 44.67600 -29.98300 29.59100  1.000 37.60748  ? 77  THR H HG1  1 
ATOM   1128 H HG21 . THR A 1 77  ? 47.80100 -29.70100 28.44000  1.000 44.17442  ? 77  THR H HG21 1 
ATOM   1129 H HG22 . THR A 1 77  ? 48.20900 -28.38900 29.21800  1.000 44.17442  ? 77  THR H HG22 1 
ATOM   1130 H HG23 . THR A 1 77  ? 48.05600 -29.75400 29.99700  1.000 44.17442  ? 77  THR H HG23 1 
ATOM   1131 N N    . VAL A 1 78  ? 44.18700 -26.68900 30.26300  1.000 33.95865  ? 78  VAL H N    1 
ATOM   1132 C CA   . VAL A 1 78  ? 42.78700 -26.33700 30.06300  1.000 30.57716  ? 78  VAL H CA   1 
ATOM   1133 C C    . VAL A 1 78  ? 42.56600 -26.24900 28.55700  1.000 29.66783  ? 78  VAL H C    1 
ATOM   1134 O O    . VAL A 1 78  ? 43.48100 -25.91900 27.79800  1.000 26.91581  ? 78  VAL H O    1 
ATOM   1135 C CB   . VAL A 1 78  ? 42.40300 -25.02500 30.78800  1.000 30.20818  ? 78  VAL H CB   1 
ATOM   1136 C CG1  . VAL A 1 78  ? 43.26400 -23.86400 30.32300  1.000 30.67917  ? 78  VAL H CG1  1 
ATOM   1137 C CG2  . VAL A 1 78  ? 40.92500 -24.72100 30.59800  1.000 29.35835  ? 78  VAL H CG2  1 
ATOM   1138 H H    . VAL A 1 78  ? 44.72900 -26.15600 29.86100  1.000 40.75395  ? 78  VAL H H    1 
ATOM   1139 H HA   . VAL A 1 78  ? 42.20500 -27.02500 30.42200  1.000 36.69617  ? 78  VAL H HA   1 
ATOM   1140 H HB   . VAL A 1 78  ? 42.56600 -25.14200 31.73700  1.000 36.25339  ? 78  VAL H HB   1 
ATOM   1141 H HG11 . VAL A 1 78  ? 43.02400 -23.07100 30.82800  1.000 36.81857  ? 78  VAL H HG11 1 
ATOM   1142 H HG12 . VAL A 1 78  ? 44.19700 -24.08300 30.47400  1.000 36.81857  ? 78  VAL H HG12 1 
ATOM   1143 H HG13 . VAL A 1 78  ? 43.10800 -23.71400 29.37800  1.000 36.81857  ? 78  VAL H HG13 1 
ATOM   1144 H HG21 . VAL A 1 78  ? 40.70500 -23.91100 31.08300  1.000 35.23359  ? 78  VAL H HG21 1 
ATOM   1145 H HG22 . VAL A 1 78  ? 40.74700 -24.60000 29.65200  1.000 35.23359  ? 78  VAL H HG22 1 
ATOM   1146 H HG23 . VAL A 1 78  ? 40.40400 -25.46400 30.94000  1.000 35.23359  ? 78  VAL H HG23 1 
ATOM   1147 N N    . THR A 1 79  ? 41.35100 -26.57400 28.12100  1.000 28.29719  ? 79  THR H N    1 
ATOM   1148 C CA   . THR A 1 79  ? 41.08000 -26.77500 26.70400  1.000 29.15786  ? 79  THR H CA   1 
ATOM   1149 C C    . THR A 1 79  ? 39.73300 -26.18100 26.32700  1.000 28.73854  ? 79  THR H C    1 
ATOM   1150 O O    . THR A 1 79  ? 38.77200 -26.24700 27.09800  1.000 29.12842  ? 79  THR H O    1 
ATOM   1151 C CB   . THR A 1 79  ? 41.11400 -28.27800 26.35800  1.000 31.12805  ? 79  THR H CB   1 
ATOM   1152 O OG1  . THR A 1 79  ? 42.45300 -28.77000 26.50500  1.000 30.13816  ? 79  THR H OG1  1 
ATOM   1153 C CG2  . THR A 1 79  ? 40.63300 -28.54500 24.93700  1.000 32.81807  ? 79  THR H CG2  1 
ATOM   1154 H H    . THR A 1 79  ? 40.66600 -26.68400 28.63000  1.000 33.96020  ? 79  THR H H    1 
ATOM   1155 H HA   . THR A 1 79  ? 41.74900 -26.31100 26.17800  1.000 34.99300  ? 79  THR H HA   1 
ATOM   1156 H HB   . THR A 1 79  ? 40.51700 -28.74900 26.96000  1.000 37.35723  ? 79  THR H HB   1 
ATOM   1157 H HG1  . THR A 1 79  ? 42.64900 -28.82900 27.32000  1.000 36.16936  ? 79  THR H HG1  1 
ATOM   1158 H HG21 . THR A 1 79  ? 40.77100 -29.47700 24.70900  1.000 39.38526  ? 79  THR H HG21 1 
ATOM   1159 H HG22 . THR A 1 79  ? 39.68800 -28.33900 24.86200  1.000 39.38526  ? 79  THR H HG22 1 
ATOM   1160 H HG23 . THR A 1 79  ? 41.12600 -27.99200 24.31000  1.000 39.38526  ? 79  THR H HG23 1 
ATOM   1161 N N    . LEU A 1 80  ? 39.67600 -25.60400 25.13000  1.000 27.72756  ? 80  LEU H N    1 
ATOM   1162 C CA   . LEU A 1 80  ? 38.44900 -25.07300 24.55800  1.000 26.24711  ? 80  LEU H CA   1 
ATOM   1163 C C    . LEU A 1 80  ? 38.15700 -25.79800 23.25400  1.000 29.37886  ? 80  LEU H C    1 
ATOM   1164 O O    . LEU A 1 80  ? 39.05700 -26.01400 22.43700  1.000 27.99743  ? 80  LEU H O    1 
ATOM   1165 C CB   . LEU A 1 80  ? 38.55800 -23.56400 24.30200  1.000 26.06768  ? 80  LEU H CB   1 
ATOM   1166 C CG   . LEU A 1 80  ? 37.46700 -22.95400 23.41600  1.000 27.34842  ? 80  LEU H CG   1 
ATOM   1167 C CD1  . LEU A 1 80  ? 36.11400 -23.00500 24.11100  1.000 26.59716  ? 80  LEU H CD1  1 
ATOM   1168 C CD2  . LEU A 1 80  ? 37.82200 -21.52500 23.01900  1.000 24.82742  ? 80  LEU H CD2  1 
ATOM   1169 H H    . LEU A 1 80  ? 40.35900 -25.50700 24.61600  1.000 33.27664  ? 80  LEU H H    1 
ATOM   1170 H HA   . LEU A 1 80  ? 37.71200 -25.21800 25.17100  1.000 31.50010  ? 80  LEU H HA   1 
ATOM   1171 H HB2  . LEU A 1 80  ? 38.52200 -23.10900 25.15700  1.000 31.28478  ? 80  LEU H HB2  1 
ATOM   1172 H HB3  . LEU A 1 80  ? 39.40900 -23.39100 23.86900  1.000 31.28478  ? 80  LEU H HB3  1 
ATOM   1173 H HG   . LEU A 1 80  ? 37.40000 -23.47700 22.60200  1.000 32.82167  ? 80  LEU H HG   1 
ATOM   1174 H HD11 . LEU A 1 80  ? 35.44500 -22.61100 23.53000  1.000 31.92016  ? 80  LEU H HD11 1 
ATOM   1175 H HD12 . LEU A 1 80  ? 35.88800 -23.93000 24.29700  1.000 31.92016  ? 80  LEU H HD12 1 
ATOM   1176 H HD13 . LEU A 1 80  ? 36.16600 -22.50500 24.94100  1.000 31.92016  ? 80  LEU H HD13 1 
ATOM   1177 H HD21 . LEU A 1 80  ? 37.11100 -21.16400 22.46700  1.000 29.79647  ? 80  LEU H HD21 1 
ATOM   1178 H HD22 . LEU A 1 80  ? 37.92200 -20.98900 23.82100  1.000 29.79647  ? 80  LEU H HD22 1 
ATOM   1179 H HD23 . LEU A 1 80  ? 38.65500 -21.53300 22.52100  1.000 29.79647  ? 80  LEU H HD23 1 
ATOM   1180 N N    . LYS A 1 81  ? 36.89400 -26.16200 23.05700  1.000 26.59570  ? 81  LYS H N    1 
ATOM   1181 C CA   . LYS A 1 81  ? 36.44100 -26.78100 21.82000  1.000 29.63778  ? 81  LYS H CA   1 
ATOM   1182 C C    . LYS A 1 81  ? 35.16800 -26.08600 21.36900  1.000 29.21749  ? 81  LYS H C    1 
ATOM   1183 O O    . LYS A 1 81  ? 34.23800 -25.91400 22.16400  1.000 30.32723  ? 81  LYS H O    1 
ATOM   1184 C CB   . LYS A 1 81  ? 36.19600 -28.28300 22.00700  1.000 32.39777  ? 81  LYS H CB   1 
ATOM   1185 C CG   . LYS A 1 81  ? 37.43200 -29.05100 22.45500  1.000 39.14838  ? 81  LYS H CG   1 
ATOM   1186 C CD   . LYS A 1 81  ? 37.14900 -30.53500 22.63800  1.000 50.88879  ? 81  LYS H CD   1 
ATOM   1187 C CE   . LYS A 1 81  ? 38.40300 -31.28300 23.07600  1.000 57.89819  ? 81  LYS H CE   1 
ATOM   1188 N NZ   . LYS A 1 81  ? 38.12300 -32.70000 23.44100  1.000 64.59865  ? 81  LYS H NZ   1 
ATOM   1189 H H    . LYS A 1 81  ? 36.26900 -26.05700 23.63900  1.000 31.91841  ? 81  LYS H H    1 
ATOM   1190 H HA   . LYS A 1 81  ? 37.11400 -26.67200 21.12900  1.000 35.56891  ? 81  LYS H HA   1 
ATOM   1191 H HB2  . LYS A 1 81  ? 35.51000 -28.40500 22.68200  1.000 38.88090  ? 81  LYS H HB2  1 
ATOM   1192 H HB3  . LYS A 1 81  ? 35.90200 -28.65900 21.16300  1.000 38.88090  ? 81  LYS H HB3  1 
ATOM   1193 H HG2  . LYS A 1 81  ? 38.12700 -28.95600 21.78400  1.000 46.98162  ? 81  LYS H HG2  1 
ATOM   1194 H HG3  . LYS A 1 81  ? 37.73900 -28.69400 23.30300  1.000 46.98162  ? 81  LYS H HG3  1 
ATOM   1195 H HD2  . LYS A 1 81  ? 36.46900 -30.65200 23.32000  1.000 61.07012  ? 81  LYS H HD2  1 
ATOM   1196 H HD3  . LYS A 1 81  ? 36.84500 -30.91200 21.79800  1.000 61.07012  ? 81  LYS H HD3  1 
ATOM   1197 H HE2  . LYS A 1 81  ? 39.04400 -31.28100 22.34800  1.000 69.48140  ? 81  LYS H HE2  1 
ATOM   1198 H HE3  . LYS A 1 81  ? 38.78100 -30.84100 23.85300  1.000 69.48140  ? 81  LYS H HE3  1 
ATOM   1199 H HZ1  . LYS A 1 81  ? 38.87700 -33.10700 23.68000  1.000 77.52195  ? 81  LYS H HZ1  1 
ATOM   1200 H HZ2  . LYS A 1 81  ? 37.54900 -32.73100 24.12100  1.000 77.52195  ? 81  LYS H HZ2  1 
ATOM   1201 H HZ3  . LYS A 1 81  ? 37.77000 -33.12900 22.74500  1.000 77.52195  ? 81  LYS H HZ3  1 
ATOM   1202 N N    . MET A 1 82  ? 35.13000 -25.67700 20.10300  1.000 28.32697  ? 82  MET H N    1 
ATOM   1203 C CA   . MET A 1 82  ? 33.94500 -25.07300 19.51000  1.000 28.68667  ? 82  MET H CA   1 
ATOM   1204 C C    . MET A 1 82  ? 33.69800 -25.70300 18.15000  1.000 32.59868  ? 82  MET H C    1 
ATOM   1205 O O    . MET A 1 82  ? 34.62900 -25.83500 17.34900  1.000 28.81670  ? 82  MET H O    1 
ATOM   1206 C CB   . MET A 1 82  ? 34.10200 -23.56100 19.35400  1.000 29.09671  ? 82  MET H CB   1 
ATOM   1207 C CG   . MET A 1 82  ? 34.15700 -22.80400 20.65600  1.000 36.47854  ? 82  MET H CG   1 
ATOM   1208 S SD   . MET A 1 82  ? 34.39300 -21.03400 20.40100  1.000 40.67082  ? 82  MET H SD   1 
ATOM   1209 C CE   . MET A 1 82  ? 33.00900 -20.64500 19.32900  1.000 28.20592  ? 82  MET H CE   1 
ATOM   1210 H H    . MET A 1 82  ? 35.79300 -25.74100 19.55900  1.000 33.99594  ? 82  MET H H    1 
ATOM   1211 H HA   . MET A 1 82  ? 33.18500 -25.23900 20.09000  1.000 34.42757  ? 82  MET H HA   1 
ATOM   1212 H HB2  . MET A 1 82  ? 34.92600 -23.38300 18.87600  1.000 34.91962  ? 82  MET H HB2  1 
ATOM   1213 H HB3  . MET A 1 82  ? 33.34600 -23.22200 18.85000  1.000 34.91962  ? 82  MET H HB3  1 
ATOM   1214 H HG2  . MET A 1 82  ? 33.32400 -22.93300 21.13500  1.000 43.77782  ? 82  MET H HG2  1 
ATOM   1215 H HG3  . MET A 1 82  ? 34.89900 -23.13500 21.18600  1.000 43.77782  ? 82  MET H HG3  1 
ATOM   1216 H HE1  . MET A 1 82  ? 33.04100 -19.70300 19.10200  1.000 33.85067  ? 82  MET H HE1  1 
ATOM   1217 H HE2  . MET A 1 82  ? 33.07300 -21.18200 18.52400  1.000 33.85067  ? 82  MET H HE2  1 
ATOM   1218 H HE3  . MET A 1 82  ? 32.18300 -20.84500 19.79500  1.000 33.85067  ? 82  MET H HE3  1 
ATOM   1219 N N    . ASN A 1 83  A 32.45100 -26.07900 17.88900  1.000 31.89677  ? 82  ASN H N    1 
ATOM   1220 C CA   . ASN A 1 83  A 32.07400 -26.75800 16.65900  1.000 33.01693  ? 82  ASN H CA   1 
ATOM   1221 C C    . ASN A 1 83  A 31.16100 -25.86900 15.82400  1.000 35.19890  ? 82  ASN H C    1 
ATOM   1222 O O    . ASN A 1 83  A 30.75600 -24.77900 16.24000  1.000 32.39702  ? 82  ASN H O    1 
ATOM   1223 C CB   . ASN A 1 83  A 31.39200 -28.09800 16.96800  1.000 37.94831  ? 82  ASN H CB   1 
ATOM   1224 C CG   . ASN A 1 83  A 30.22200 -27.95700 17.92000  1.000 42.09884  ? 82  ASN H CG   1 
ATOM   1225 O OD1  . ASN A 1 83  A 29.40900 -27.03800 17.80000  1.000 42.63757  ? 82  ASN H OD1  1 
ATOM   1226 N ND2  . ASN A 1 83  A 30.13600 -28.86700 18.88300  1.000 43.29882  ? 82  ASN H ND2  1 
ATOM   1227 H H    . ASN A 1 83  A 31.79100 -25.94700 18.42400  1.000 38.27970  ? 82  ASN H H    1 
ATOM   1228 H HA   . ASN A 1 83  A 32.87100 -26.94100 16.13700  1.000 39.62388  ? 82  ASN H HA   1 
ATOM   1229 H HB2  . ASN A 1 83  A 31.06100 -28.48200 16.14100  1.000 45.54154  ? 82  ASN H HB2  1 
ATOM   1230 H HB3  . ASN A 1 83  A 32.03900 -28.69600 17.37500  1.000 45.54154  ? 82  ASN H HB3  1 
ATOM   1231 H HD21 . ASN A 1 83  A 29.49000 -28.83300 19.45000  1.000 51.96215  ? 82  ASN H HD21 1 
ATOM   1232 H HD22 . ASN A 1 83  A 30.72500 -29.49100 18.93800  1.000 51.96215  ? 82  ASN H HD22 1 
ATOM   1233 N N    . SER A 1 84  B 30.85300 -26.34900 14.62000  1.000 31.31606  ? 82  SER H N    1 
ATOM   1234 C CA   . SER A 1 84  B 29.97900 -25.63900 13.68900  1.000 35.25784  ? 82  SER H CA   1 
ATOM   1235 C C    . SER A 1 84  B 30.46700 -24.21000 13.46100  1.000 30.69637  ? 82  SER H C    1 
ATOM   1236 O O    . SER A 1 84  B 29.71800 -23.24000 13.59400  1.000 32.22692  ? 82  SER H O    1 
ATOM   1237 C CB   . SER A 1 84  B 28.53400 -25.64900 14.19200  1.000 40.04783  ? 82  SER H CB   1 
ATOM   1238 O OG   . SER A 1 84  B 28.06100 -26.97500 14.36000  1.000 47.26812  ? 82  SER H OG   1 
ATOM   1239 H H    . SER A 1 84  B 31.14400 -27.09800 14.31400  1.000 37.58284  ? 82  SER H H    1 
ATOM   1240 H HA   . SER A 1 84  B 30.00600 -26.09700 12.83400  1.000 42.31298  ? 82  SER H HA   1 
ATOM   1241 H HB2  . SER A 1 84  B 28.49500 -25.19000 15.04600  1.000 48.06096  ? 82  SER H HB2  1 
ATOM   1242 H HB3  . SER A 1 84  B 27.97200 -25.19400 13.54500  1.000 48.06096  ? 82  SER H HB3  1 
ATOM   1243 H HG   . SER A 1 84  B 27.28400 -26.96400 14.68100  1.000 56.72531  ? 82  SER H HG   1 
ATOM   1244 N N    . LEU A 1 85  C 31.74000 -24.08500 13.09900  1.000 28.57654  ? 82  LEU H N    1 
ATOM   1245 C CA   . LEU A 1 85  C 32.35800 -22.77400 12.96600  1.000 29.09783  ? 82  LEU H CA   1 
ATOM   1246 C C    . LEU A 1 85  C 31.96300 -22.10400 11.65400  1.000 29.48814  ? 82  LEU H C    1 
ATOM   1247 O O    . LEU A 1 85  C 31.68200 -22.76400 10.64900  1.000 26.16639  ? 82  LEU H O    1 
ATOM   1248 C CB   . LEU A 1 85  C 33.87800 -22.89400 13.04700  1.000 26.42691  ? 82  LEU H CB   1 
ATOM   1249 C CG   . LEU A 1 85  C 34.41200 -23.34300 14.40700  1.000 28.60798  ? 82  LEU H CG   1 
ATOM   1250 C CD1  . LEU A 1 85  C 35.91800 -23.46300 14.35500  1.000 33.68032  ? 82  LEU H CD1  1 
ATOM   1251 C CD2  . LEU A 1 85  C 33.99000 -22.37900 15.50800  1.000 30.38897  ? 82  LEU H CD2  1 
ATOM   1252 H H    . LEU A 1 85  C 32.26500 -24.74300 12.92500  1.000 34.29542  ? 82  LEU H H    1 
ATOM   1253 H HA   . LEU A 1 85  C 32.05300 -22.20600 13.69000  1.000 34.92096  ? 82  LEU H HA   1 
ATOM   1254 H HB2  . LEU A 1 85  C 34.17200 -23.54300 12.38900  1.000 31.71586  ? 82  LEU H HB2  1 
ATOM   1255 H HB3  . LEU A 1 85  C 34.26600 -22.02600 12.85300  1.000 31.71586  ? 82  LEU H HB3  1 
ATOM   1256 H HG   . LEU A 1 85  C 34.03700 -24.21200 14.62200  1.000 34.33315  ? 82  LEU H HG   1 
ATOM   1257 H HD11 . LEU A 1 85  C 36.23900 -23.79100 15.21000  1.000 40.41996  ? 82  LEU H HD11 1 
ATOM   1258 H HD12 . LEU A 1 85  C 36.16200 -24.08300 13.65100  1.000 40.41996  ? 82  LEU H HD12 1 
ATOM   1259 H HD13 . LEU A 1 85  C 36.29900 -22.58900 14.17300  1.000 40.41996  ? 82  LEU H HD13 1 
ATOM   1260 H HD21 . LEU A 1 85  C 34.46800 -22.60200 16.32300  1.000 36.47034  ? 82  LEU H HD21 1 
ATOM   1261 H HD22 . LEU A 1 85  C 34.20600 -21.47400 15.23500  1.000 36.47034  ? 82  LEU H HD22 1 
ATOM   1262 H HD23 . LEU A 1 85  C 33.03400 -22.46200 15.65200  1.000 36.47034  ? 82  LEU H HD23 1 
ATOM   1263 N N    . ARG A 1 86  ? 31.94400 -20.77300 11.67800  1.000 28.81652  ? 83  ARG H N    1 
ATOM   1264 C CA   . ARG A 1 86  ? 31.70600 -19.95900 10.49600  1.000 31.80799  ? 83  ARG H CA   1 
ATOM   1265 C C    . ARG A 1 86  ? 32.73400 -18.83600 10.45300  1.000 28.55795  ? 83  ARG H C    1 
ATOM   1266 O O    . ARG A 1 86  ? 33.42500 -18.55800 11.43800  1.000 24.61588  ? 83  ARG H O    1 
ATOM   1267 C CB   . ARG A 1 86  ? 30.28300 -19.38300 10.48600  1.000 36.66795  ? 83  ARG H CB   1 
ATOM   1268 C CG   . ARG A 1 86  ? 29.19400 -20.43400 10.66900  1.000 40.20822  ? 83  ARG H CG   1 
ATOM   1269 C CD   . ARG A 1 86  ? 27.79500 -19.83200 10.62900  1.000 49.63804  ? 83  ARG H CD   1 
ATOM   1270 N NE   . ARG A 1 86  ? 27.72800 -18.53100 11.28600  1.000 55.27837  ? 83  ARG H NE   1 
ATOM   1271 C CZ   . ARG A 1 86  ? 27.85400 -18.33800 12.59300  1.000 56.38797  ? 83  ARG H CZ   1 
ATOM   1272 N NH1  . ARG A 1 86  ? 28.08300 -19.34300 13.42300  1.000 52.51908  ? 83  ARG H NH1  1 
ATOM   1273 N NH2  . ARG A 1 86  ? 27.75700 -17.10300 13.07800  1.000 58.65818  ? 83  ARG H NH2  1 
ATOM   1274 H H    . ARG A 1 86  ? 32.07000 -20.30800 12.39100  1.000 34.58339  ? 83  ARG H H    1 
ATOM   1275 H HA   . ARG A 1 86  ? 31.81200 -20.50400 9.70100   1.000 38.17315  ? 83  ARG H HA   1 
ATOM   1276 H HB2  . ARG A 1 86  ? 30.20000 -18.74300 11.21000  1.000 44.00511  ? 83  ARG H HB2  1 
ATOM   1277 H HB3  . ARG A 1 86  ? 30.13000 -18.94400 9.63500   1.000 44.00511  ? 83  ARG H HB3  1 
ATOM   1278 H HG2  . ARG A 1 86  ? 29.26100 -21.08800 9.95700   1.000 48.25344  ? 83  ARG H HG2  1 
ATOM   1279 H HG3  . ARG A 1 86  ? 29.31200 -20.86700 11.52900  1.000 48.25344  ? 83  ARG H HG3  1 
ATOM   1280 H HD2  . ARG A 1 86  ? 27.52500 -19.71600 9.70500   1.000 59.56922  ? 83  ARG H HD2  1 
ATOM   1281 H HD3  . ARG A 1 86  ? 27.17900 -20.42900 11.08200  1.000 59.56922  ? 83  ARG H HD3  1 
ATOM   1282 H HE   . ARG A 1 86  ? 27.59800 -17.84000 10.79100  1.000 66.33762  ? 83  ARG H HE   1 
ATOM   1283 H HH11 . ARG A 1 86  ? 28.15300 -20.14400 13.11900  1.000 63.02647  ? 83  ARG H HH11 1 
ATOM   1284 H HH12 . ARG A 1 86  ? 28.16100 -19.19400 14.26600  1.000 63.02647  ? 83  ARG H HH12 1 
ATOM   1285 H HH21 . ARG A 1 86  ? 27.61400 -16.44200 12.54600  1.000 70.39338  ? 83  ARG H HH21 1 
ATOM   1286 H HH22 . ARG A 1 86  ? 27.83700 -16.96500 13.92300  1.000 70.39338  ? 83  ARG H HH22 1 
ATOM   1287 N N    . ALA A 1 87  ? 32.82800 -18.17900 9.29400   1.000 28.62770  ? 84  ALA H N    1 
ATOM   1288 C CA   . ALA A 1 87  ? 33.80300 -17.10600 9.13400   1.000 28.64827  ? 84  ALA H CA   1 
ATOM   1289 C C    . ALA A 1 87  ? 33.75200 -16.12600 10.29900  1.000 28.44729  ? 84  ALA H C    1 
ATOM   1290 O O    . ALA A 1 87  ? 34.78200 -15.55600 10.67600  1.000 30.08986  ? 84  ALA H O    1 
ATOM   1291 C CB   . ALA A 1 87  ? 33.56800 -16.37300 7.81100   1.000 27.62815  ? 84  ALA H CB   1 
ATOM   1292 H H    . ALA A 1 87  ? 32.34600 -18.33400 8.59800   1.000 34.35681  ? 84  ALA H H    1 
ATOM   1293 H HA   . ALA A 1 87  ? 34.69300 -17.49200 9.10600   1.000 34.38149  ? 84  ALA H HA   1 
ATOM   1294 H HB1  . ALA A 1 87  ? 34.23600 -15.67700 7.71200   1.000 33.15735  ? 84  ALA H HB1  1 
ATOM   1295 H HB2  . ALA A 1 87  ? 33.64300 -17.00800 7.08100   1.000 33.15735  ? 84  ALA H HB2  1 
ATOM   1296 H HB3  . ALA A 1 87  ? 32.68100 -15.98200 7.81900   1.000 33.15735  ? 84  ALA H HB3  1 
ATOM   1297 N N    . GLU A 1 88  ? 32.57100 -15.93800 10.89700  1.000 28.16627  ? 85  GLU H N    1 
ATOM   1298 C CA   . GLU A 1 88  ? 32.42600 -15.01200 12.01500  1.000 28.98750  ? 85  GLU H CA   1 
ATOM   1299 C C    . GLU A 1 88  ? 33.24600 -15.42800 13.23000  1.000 28.66936  ? 85  GLU H C    1 
ATOM   1300 O O    . GLU A 1 88  ? 33.50000 -14.59700 14.10900  1.000 27.94954  ? 85  GLU H O    1 
ATOM   1301 C CB   . GLU A 1 88  ? 30.94800 -14.89800 12.40500  1.000 35.66833  ? 85  GLU H CB   1 
ATOM   1302 C CG   . GLU A 1 88  ? 30.07800 -14.15100 11.39000  1.000 45.50815  ? 85  GLU H CG   1 
ATOM   1303 C CD   . GLU A 1 88  ? 29.88100 -14.91000 10.08400  1.000 51.25813  ? 85  GLU H CD   1 
ATOM   1304 O OE1  . GLU A 1 88  ? 30.06900 -16.14500 10.07100  1.000 46.38851  ? 85  GLU H OE1  1 
ATOM   1305 O OE2  . GLU A 1 88  ? 29.54200 -14.26900 9.06500   1.000 49.51904  ? 85  GLU H OE2  1 
ATOM   1306 H H    . GLU A 1 88  ? 31.84200 -16.33500 10.67300  1.000 33.80309  ? 85  GLU H H    1 
ATOM   1307 H HA   . GLU A 1 88  ? 32.73900 -14.13800 11.73300  1.000 34.78857  ? 85  GLU H HA   1 
ATOM   1308 H HB2  . GLU A 1 88  ? 30.58400 -15.79200 12.50000  1.000 42.80557  ? 85  GLU H HB2  1 
ATOM   1309 H HB3  . GLU A 1 88  ? 30.88700 -14.42300 13.24800  1.000 42.80557  ? 85  GLU H HB3  1 
ATOM   1310 H HG2  . GLU A 1 88  ? 29.20300 -13.99800 11.78000  1.000 54.61335  ? 85  GLU H HG2  1 
ATOM   1311 H HG3  . GLU A 1 88  ? 30.50000 -13.30300 11.18000  1.000 54.61335  ? 85  GLU H HG3  1 
ATOM   1312 N N    . ASP A 1 89  ? 33.66600 -16.68500 13.29600  1.000 22.65533  ? 86  ASP H N    1 
ATOM   1313 C CA   . ASP A 1 89  ? 34.42200 -17.20600 14.42500  1.000 22.58615  ? 86  ASP H CA   1 
ATOM   1314 C C    . ASP A 1 89  ? 35.92500 -17.01400 14.28000  1.000 22.79928  ? 86  ASP H C    1 
ATOM   1315 O O    . ASP A 1 89  ? 36.67100 -17.35500 15.20400  1.000 19.76723  ? 86  ASP H O    1 
ATOM   1316 C CB   . ASP A 1 89  ? 34.10000 -18.69000 14.60200  1.000 25.34789  ? 86  ASP H CB   1 
ATOM   1317 C CG   . ASP A 1 89  ? 32.64300 -18.92400 14.94600  1.000 29.90983  ? 86  ASP H CG   1 
ATOM   1318 O OD1  . ASP A 1 89  ? 32.14000 -18.25600 15.87700  1.000 28.27818  ? 86  ASP H OD1  1 
ATOM   1319 O OD2  . ASP A 1 89  ? 31.99900 -19.76100 14.28000  1.000 29.28819  ? 86  ASP H OD2  1 
ATOM   1320 H H    . ASP A 1 89  ? 33.52100 -17.27100 12.68400  1.000 27.18997  ? 86  ASP H H    1 
ATOM   1321 H HA   . ASP A 1 89  ? 34.15400 -16.73700 15.23100  1.000 27.10695  ? 86  ASP H HA   1 
ATOM   1322 H HB2  . ASP A 1 89  ? 34.29500 -19.15900 13.77500  1.000 30.42103  ? 86  ASP H HB2  1 
ATOM   1323 H HB3  . ASP A 1 89  ? 34.64200 -19.04900 15.32200  1.000 30.42103  ? 86  ASP H HB3  1 
ATOM   1324 N N    . THR A 1 90  ? 36.38800 -16.48700 13.15100  1.000 18.78524  ? 87  THR H N    1 
ATOM   1325 C CA   . THR A 1 90  ? 37.80100 -16.17000 13.00700  1.000 19.04728  ? 87  THR H CA   1 
ATOM   1326 C C    . THR A 1 90  ? 38.18800 -15.11900 14.03800  1.000 19.67802  ? 87  THR H C    1 
ATOM   1327 O O    . THR A 1 90  ? 37.56400 -14.05900 14.12100  1.000 19.23694  ? 87  THR H O    1 
ATOM   1328 C CB   . THR A 1 90  ? 38.07600 -15.67000 11.58900  1.000 20.55826  ? 87  THR H CB   1 
ATOM   1329 O OG1  . THR A 1 90  ? 37.86600 -16.74500 10.66100  1.000 20.02802  ? 87  THR H OG1  1 
ATOM   1330 C CG2  . THR A 1 90  ? 39.50200 -15.15300 11.45700  1.000 20.96881  ? 87  THR H CG2  1 
ATOM   1331 H H    . THR A 1 90  ? 35.90800 -16.30600 12.46100  1.000 22.54586  ? 87  THR H H    1 
ATOM   1332 H HA   . THR A 1 90  ? 38.34400 -16.96000 13.15200  1.000 22.86030  ? 87  THR H HA   1 
ATOM   1333 H HB   . THR A 1 90  ? 37.47500 -14.93700 11.38300  1.000 24.67349  ? 87  THR H HB   1 
ATOM   1334 H HG1  . THR A 1 90  ? 37.95200 -16.46500 9.87300   1.000 24.03719  ? 87  THR H HG1  1 
ATOM   1335 H HG21 . THR A 1 90  ? 39.70300 -14.96700 10.52700  1.000 25.16614  ? 87  THR H HG21 1 
ATOM   1336 H HG22 . THR A 1 90  ? 39.60700 -14.33700 11.97100  1.000 25.16614  ? 87  THR H HG22 1 
ATOM   1337 H HG23 . THR A 1 90  ? 40.12700 -15.81600 11.78800  1.000 25.16614  ? 87  THR H HG23 1 
ATOM   1338 N N    . ALA A 1 91  ? 39.21100 -15.41800 14.83500  1.000 17.53648  ? 88  ALA H N    1 
ATOM   1339 C CA   . ALA A 1 91  ? 39.62100 -14.52400 15.91200  1.000 18.90911  ? 88  ALA H CA   1 
ATOM   1340 C C    . ALA A 1 91  ? 40.89500 -15.06400 16.54300  1.000 17.99823  ? 88  ALA H C    1 
ATOM   1341 O O    . ALA A 1 91  ? 41.28500 -16.21200 16.31800  1.000 17.59816  ? 88  ALA H O    1 
ATOM   1342 C CB   . ALA A 1 91  ? 38.52200 -14.38400 16.97000  1.000 17.52700  ? 88  ALA H CB   1 
ATOM   1343 H H    . ALA A 1 91  ? 39.68400 -16.13300 14.77200  1.000 21.04734  ? 88  ALA H H    1 
ATOM   1344 H HA   . ALA A 1 91  ? 39.81400 -13.65100 15.53500  1.000 22.69451  ? 88  ALA H HA   1 
ATOM   1345 H HB1  . ALA A 1 91  ? 38.84100 -13.80700 17.68200  1.000 21.03597  ? 88  ALA H HB1  1 
ATOM   1346 H HB2  . ALA A 1 91  ? 37.73400 -13.99500 16.55800  1.000 21.03597  ? 88  ALA H HB2  1 
ATOM   1347 H HB3  . ALA A 1 91  ? 38.31100 -15.26100 17.32500  1.000 21.03597  ? 88  ALA H HB3  1 
ATOM   1348 N N    . VAL A 1 92  ? 41.53700 -14.21600 17.33900  1.000 14.18549  ? 89  VAL H N    1 
ATOM   1349 C CA   . VAL A 1 92  ? 42.63800 -14.63500 18.19900  1.000 15.77636  ? 89  VAL H CA   1 
ATOM   1350 C C    . VAL A 1 92  ? 42.01700 -15.11000 19.50500  1.000 17.57719  ? 89  VAL H C    1 
ATOM   1351 O O    . VAL A 1 92  ? 41.26600 -14.36500 20.14300  1.000 15.69694  ? 89  VAL H O    1 
ATOM   1352 C CB   . VAL A 1 92  ? 43.63400 -13.49200 18.43800  1.000 17.97725  ? 89  VAL H CB   1 
ATOM   1353 C CG1  . VAL A 1 92  ? 44.72200 -13.93000 19.41900  1.000 19.32695  ? 89  VAL H CG1  1 
ATOM   1354 C CG2  . VAL A 1 92  ? 44.25600 -13.02700 17.12400  1.000 19.61720  ? 89  VAL H CG2  1 
ATOM   1355 H H    . VAL A 1 92  ? 41.35100 -13.37800 17.40100  1.000 17.02616  ? 89  VAL H H    1 
ATOM   1356 H HA   . VAL A 1 92  ? 43.12600 -15.36500 17.78700  1.000 18.93521  ? 89  VAL H HA   1 
ATOM   1357 H HB   . VAL A 1 92  ? 43.15600 -12.74100 18.82500  1.000 21.57628  ? 89  VAL H HB   1 
ATOM   1358 H HG11 . VAL A 1 92  ? 45.39200 -13.23100 19.48000  1.000 23.19591  ? 89  VAL H HG11 1 
ATOM   1359 H HG12 . VAL A 1 92  ? 44.32100 -14.08000 20.28900  1.000 23.19591  ? 89  VAL H HG12 1 
ATOM   1360 H HG13 . VAL A 1 92  ? 45.12800 -14.74900 19.09600  1.000 23.19591  ? 89  VAL H HG13 1 
ATOM   1361 H HG21 . VAL A 1 92  ? 44.92000 -12.34600 17.31200  1.000 23.54421  ? 89  VAL H HG21 1 
ATOM   1362 H HG22 . VAL A 1 92  ? 44.67500 -13.78600 16.68700  1.000 23.54421  ? 89  VAL H HG22 1 
ATOM   1363 H HG23 . VAL A 1 92  ? 43.56000 -12.66200 16.55600  1.000 23.54421  ? 89  VAL H HG23 1 
ATOM   1364 N N    . TYR A 1 93  ? 42.30600 -16.35200 19.88900  1.000 15.94668  ? 90  TYR H N    1 
ATOM   1365 C CA   . TYR A 1 93  ? 41.75500 -16.96800 21.09200  1.000 19.34875  ? 90  TYR H CA   1 
ATOM   1366 C C    . TYR A 1 93  ? 42.81700 -16.96700 22.18100  1.000 18.24636  ? 90  TYR H C    1 
ATOM   1367 O O    . TYR A 1 93  ? 43.97400 -17.30800 21.91800  1.000 19.30689  ? 90  TYR H O    1 
ATOM   1368 C CB   . TYR A 1 93  ? 41.27700 -18.39500 20.79900  1.000 16.90640  ? 90  TYR H CB   1 
ATOM   1369 C CG   . TYR A 1 93  ? 40.01600 -18.41900 19.96500  1.000 18.77779  ? 90  TYR H CG   1 
ATOM   1370 C CD1  . TYR A 1 93  ? 40.05200 -18.11500 18.61000  1.000 17.32748  ? 90  TYR H CD1  1 
ATOM   1371 C CD2  . TYR A 1 93  ? 38.78600 -18.71700 20.53600  1.000 19.38818  ? 90  TYR H CD2  1 
ATOM   1372 C CE1  . TYR A 1 93  ? 38.90200 -18.11400 17.84600  1.000 17.63822  ? 90  TYR H CE1  1 
ATOM   1373 C CE2  . TYR A 1 93  ? 37.62700 -18.72000 19.77700  1.000 19.00774  ? 90  TYR H CE2  1 
ATOM   1374 C CZ   . TYR A 1 93  ? 37.69200 -18.41600 18.43400  1.000 18.91751  ? 90  TYR H CZ   1 
ATOM   1375 O OH   . TYR A 1 93  ? 36.54700 -18.40900 17.67200  1.000 18.91756  ? 90  TYR H OH   1 
ATOM   1376 H H    . TYR A 1 93  ? 42.83600 -16.87300 19.45500  1.000 19.13959  ? 90  TYR H H    1 
ATOM   1377 H HA   . TYR A 1 93  ? 40.99300 -16.45800 21.40900  1.000 23.22208  ? 90  TYR H HA   1 
ATOM   1378 H HB2  . TYR A 1 93  ? 41.97000 -18.86800 20.31200  1.000 20.29125  ? 90  TYR H HB2  1 
ATOM   1379 H HB3  . TYR A 1 93  ? 41.09300 -18.84700 21.63700  1.000 20.29125  ? 90  TYR H HB3  1 
ATOM   1380 H HD1  . TYR A 1 93  ? 40.86600 -17.90800 18.21000  1.000 20.79655  ? 90  TYR H HD1  1 
ATOM   1381 H HD2  . TYR A 1 93  ? 38.74000 -18.91900 21.44300  1.000 23.26938  ? 90  TYR H HD2  1 
ATOM   1382 H HE1  . TYR A 1 93  ? 38.94400 -17.91000 16.94000  1.000 21.16944  ? 90  TYR H HE1  1 
ATOM   1383 H HE2  . TYR A 1 93  ? 36.81000 -18.92500 20.17100  1.000 22.81286  ? 90  TYR H HE2  1 
ATOM   1384 H HH   . TYR A 1 93  ? 36.72400 -18.16200 16.88900  1.000 22.70464  ? 90  TYR H HH   1 
ATOM   1385 N N    . TYR A 1 94  ? 42.43000 -16.56200 23.39100  1.000 20.75843  ? 91  TYR H N    1 
ATOM   1386 C CA   . TYR A 1 94  ? 43.33500 -16.54800 24.52700  1.000 18.57615  ? 91  TYR H CA   1 
ATOM   1387 C C    . TYR A 1 94  ? 42.76000 -17.37100 25.67200  1.000 20.01655  ? 91  TYR H C    1 
ATOM   1388 O O    . TYR A 1 94  ? 41.54400 -17.41000 25.88400  1.000 19.74734  ? 91  TYR H O    1 
ATOM   1389 C CB   . TYR A 1 94  ? 43.58600 -15.14000 25.09500  1.000 20.53905  ? 91  TYR H CB   1 
ATOM   1390 C CG   . TYR A 1 94  ? 44.13200 -14.09500 24.16300  1.000 17.75601  ? 91  TYR H CG   1 
ATOM   1391 C CD1  . TYR A 1 94  ? 43.27900 -13.29900 23.41900  1.000 18.02656  ? 91  TYR H CD1  1 
ATOM   1392 C CD2  . TYR A 1 94  ? 45.49500 -13.85400 24.07600  1.000 19.78756  ? 91  TYR H CD2  1 
ATOM   1393 C CE1  . TYR A 1 94  ? 43.76700 -12.31300 22.58200  1.000 19.98837  ? 91  TYR H CE1  1 
ATOM   1394 C CE2  . TYR A 1 94  ? 45.99500 -12.86900 23.23700  1.000 21.04744  ? 91  TYR H CE2  1 
ATOM   1395 C CZ   . TYR A 1 94  ? 45.12600 -12.10200 22.49600  1.000 19.94656  ? 91  TYR H CZ   1 
ATOM   1396 O OH   . TYR A 1 94  ? 45.61600 -11.12200 21.66000  1.000 23.22815  ? 91  TYR H OH   1 
ATOM   1397 H H    . TYR A 1 94  ? 41.63600 -16.28800 23.57600  1.000 24.91369  ? 91  TYR H H    1 
ATOM   1398 H HA   . TYR A 1 94  ? 44.17400 -16.92100 24.21400  1.000 22.29495  ? 91  TYR H HA   1 
ATOM   1399 H HB2  . TYR A 1 94  ? 42.74000 -14.80100 25.43000  1.000 24.65043  ? 91  TYR H HB2  1 
ATOM   1400 H HB3  . TYR A 1 94  ? 44.22100 -15.22400 25.82300  1.000 24.65043  ? 91  TYR H HB3  1 
ATOM   1401 H HD1  . TYR A 1 94  ? 42.36000 -13.43000 23.48400  1.000 21.63544  ? 91  TYR H HD1  1 
ATOM   1402 H HD2  . TYR A 1 94  ? 46.08300 -14.36200 24.58800  1.000 23.74864  ? 91  TYR H HD2  1 
ATOM   1403 H HE1  . TYR A 1 94  ? 43.18100 -11.79400 22.08000  1.000 23.98962  ? 91  TYR H HE1  1 
ATOM   1404 H HE2  . TYR A 1 94  ? 46.91300 -12.72700 23.17700  1.000 25.26050  ? 91  TYR H HE2  1 
ATOM   1405 H HH   . TYR A 1 94  ? 44.98100 -10.70800 21.29800  1.000 27.87735  ? 91  TYR H HH   1 
ATOM   1406 N N    . CYS A 1 95  ? 43.64800 -17.99700 26.42800  1.000 20.69663  ? 92  CYS H N    1 
ATOM   1407 C CA   . CYS A 1 95  ? 43.32600 -18.50900 27.75200  0.890 23.36769  ? 92  CYS H CA   1 
ATOM   1408 C C    . CYS A 1 95  ? 43.86100 -17.51800 28.77500  1.000 21.99656  ? 92  CYS H C    1 
ATOM   1409 O O    . CYS A 1 95  ? 44.94400 -16.95400 28.59200  1.000 22.30684  ? 92  CYS H O    1 
ATOM   1410 C CB   . CYS A 1 95  ? 43.94700 -19.88000 27.97100  1.000 25.20762  ? 92  CYS H CB   1 
ATOM   1411 S SG   . CYS A 1 95  ? 45.72700 -19.84900 27.79500  1.000 31.16948  ? 92  CYS H SG   1 
ATOM   1412 H H    . CYS A 1 95  ? 44.46200 -18.14200 26.19200  1.000 24.83952  ? 92  CYS H H    1 
ATOM   1413 H HA   . CYS A 1 95  ? 42.36800 -18.60700 27.86300  0.950 28.04479  ? 92  CYS H HA   1 
ATOM   1414 H HB2  . CYS A 1 95  ? 43.73600 -20.18500 28.86700  1.000 30.25272  ? 92  CYS H HB2  1 
ATOM   1415 H HB3  . CYS A 1 95  ? 43.58800 -20.50000 27.31700  1.000 30.25272  ? 92  CYS H HB3  1 
ATOM   1416 N N    . ALA A 1 96  ? 43.10600 -17.29400 29.84600  1.000 23.67782  ? 93  ALA H N    1 
ATOM   1417 C CA   . ALA A 1 96  ? 43.51200 -16.25600 30.78100  1.000 24.02783  ? 93  ALA H CA   1 
ATOM   1418 C C    . ALA A 1 96  ? 42.81000 -16.41300 32.11500  1.000 22.16640  ? 93  ALA H C    1 
ATOM   1419 O O    . ALA A 1 96  ? 41.59600 -16.62600 32.16200  1.000 24.03862  ? 93  ALA H O    1 
ATOM   1420 C CB   . ALA A 1 96  ? 43.20600 -14.86400 30.21400  1.000 21.69712  ? 93  ALA H CB   1 
ATOM   1421 H H    . ALA A 1 96  ? 42.38200 -17.71400 30.04400  1.000 28.41696  ? 93  ALA H H    1 
ATOM   1422 H HA   . ALA A 1 96  ? 44.46400 -16.35700 30.93700  1.000 28.83697  ? 93  ALA H HA   1 
ATOM   1423 H HB1  . ALA A 1 96  ? 43.49500 -14.19300 30.85200  1.000 26.04012  ? 93  ALA H HB1  1 
ATOM   1424 H HB2  . ALA A 1 96  ? 43.68400 -14.75200 29.37700  1.000 26.04012  ? 93  ALA H HB2  1 
ATOM   1425 H HB3  . ALA A 1 96  ? 42.25100 -14.78800 30.06300  1.000 26.04012  ? 93  ALA H HB3  1 
ATOM   1426 N N    . LYS A 1 97  ? 43.57700 -16.28700 33.19000  1.000 23.30576  ? 94  LYS H N    1 
ATOM   1427 C CA   . LYS A 1 97  ? 43.02900 -15.96400 34.50100  1.000 25.96893  ? 94  LYS H CA   1 
ATOM   1428 C C    . LYS A 1 97  ? 42.96400 -14.44300 34.56900  1.000 21.89626  ? 94  LYS H C    1 
ATOM   1429 O O    . LYS A 1 97  ? 43.99700 -13.78200 34.71100  1.000 20.81518  ? 94  LYS H O    1 
ATOM   1430 C CB   . LYS A 1 97  ? 43.89000 -16.53700 35.61800  1.000 28.11785  ? 94  LYS H CB   1 
ATOM   1431 C CG   . LYS A 1 97  ? 43.29800 -16.33200 37.01000  1.000 32.71871  ? 94  LYS H CG   1 
ATOM   1432 C CD   . LYS A 1 97  ? 44.33800 -16.56800 38.09600  1.000 35.41818  ? 94  LYS H CD   1 
ATOM   1433 C CE   . LYS A 1 97  ? 43.72900 -16.46800 39.48500  1.000 33.66861  ? 94  LYS H CE   1 
ATOM   1434 N NZ   . LYS A 1 97  ? 43.10100 -15.14000 39.71300  1.000 29.24742  ? 94  LYS H NZ   1 
ATOM   1435 H H    . LYS A 1 97  ? 44.43100 -16.38500 33.18600  1.000 27.97048  ? 94  LYS H H    1 
ATOM   1436 H HA   . LYS A 1 97  ? 42.14200 -16.34400 34.60700  1.000 31.16629  ? 94  LYS H HA   1 
ATOM   1437 H HB2  . LYS A 1 97  ? 43.99200 -17.49200 35.47700  1.000 33.74499  ? 94  LYS H HB2  1 
ATOM   1438 H HB3  . LYS A 1 97  ? 44.75800 -16.10400 35.59800  1.000 33.74499  ? 94  LYS H HB3  1 
ATOM   1439 H HG2  . LYS A 1 97  ? 42.97400 -15.42100 37.09100  1.000 39.26603  ? 94  LYS H HG2  1 
ATOM   1440 H HG3  . LYS A 1 97  ? 42.56800 -16.95700 37.14500  1.000 39.26603  ? 94  LYS H HG3  1 
ATOM   1441 H HD2  . LYS A 1 97  ? 44.71500 -17.45600 37.99200  1.000 42.50539  ? 94  LYS H HD2  1 
ATOM   1442 H HD3  . LYS A 1 97  ? 45.03700 -15.90100 38.02100  1.000 42.50539  ? 94  LYS H HD3  1 
ATOM   1443 H HE2  . LYS A 1 97  ? 43.04600 -17.15000 39.58600  1.000 40.40590  ? 94  LYS H HE2  1 
ATOM   1444 H HE3  . LYS A 1 97  ? 44.42400 -16.59500 40.15000  1.000 40.40590  ? 94  LYS H HE3  1 
ATOM   1445 H HZ1  . LYS A 1 97  ? 42.82100 -15.07600 40.55600  1.000 35.10047  ? 94  LYS H HZ1  1 
ATOM   1446 H HZ2  . LYS A 1 97  ? 43.69100 -14.49200 39.55600  1.000 35.10047  ? 94  LYS H HZ2  1 
ATOM   1447 H HZ3  . LYS A 1 97  ? 42.40500 -15.03400 39.16900  1.000 35.10047  ? 94  LYS H HZ3  1 
ATOM   1448 N N    . LEU A 1 98  ? 41.76000 -13.88400 34.44900  1.000 21.07499  ? 95  LEU H N    1 
ATOM   1449 C CA   . LEU A 1 98  ? 41.63600 -12.45200 34.19100  1.000 21.11736  ? 95  LEU H CA   1 
ATOM   1450 C C    . LEU A 1 98  ? 42.03100 -11.58300 35.38100  1.000 22.94800  ? 95  LEU H C    1 
ATOM   1451 O O    . LEU A 1 98  ? 42.38400 -10.41600 35.18200  1.000 22.28727  ? 95  LEU H O    1 
ATOM   1452 C CB   . LEU A 1 98  ? 40.20600 -12.13100 33.75500  1.000 20.51711  ? 95  LEU H CB   1 
ATOM   1453 C CG   . LEU A 1 98  ? 39.81400 -12.76400 32.41800  1.000 20.02696  ? 95  LEU H CG   1 
ATOM   1454 C CD1  . LEU A 1 98  ? 38.33100 -12.59400 32.15800  1.000 20.53799  ? 95  LEU H CD1  1 
ATOM   1455 C CD2  . LEU A 1 98  ? 40.63600 -12.17300 31.27700  1.000 22.25904  ? 95  LEU H CD2  1 
ATOM   1456 H H    . LEU A 1 98  ? 41.01200 -14.30400 34.51300  1.000 25.29356  ? 95  LEU H H    1 
ATOM   1457 H HA   . LEU A 1 98  ? 42.23800 -12.22100 33.46600  1.000 25.34440  ? 95  LEU H HA   1 
ATOM   1458 H HB2  . LEU A 1 98  ? 39.59300 -12.46100 34.43100  1.000 24.62410  ? 95  LEU H HB2  1 
ATOM   1459 H HB3  . LEU A 1 98  ? 40.11500 -11.16900 33.66700  1.000 24.62410  ? 95  LEU H HB3  1 
ATOM   1460 H HG   . LEU A 1 98  ? 40.00300 -13.71500 32.45500  1.000 24.03592  ? 95  LEU H HG   1 
ATOM   1461 H HD11 . LEU A 1 98  ? 38.12300 -12.94100 31.27700  1.000 24.64916  ? 95  LEU H HD11 1 
ATOM   1462 H HD12 . LEU A 1 98  ? 37.83500 -13.08400 32.83200  1.000 24.64916  ? 95  LEU H HD12 1 
ATOM   1463 H HD13 . LEU A 1 98  ? 38.10900 -11.65100 32.20300  1.000 24.64916  ? 95  LEU H HD13 1 
ATOM   1464 H HD21 . LEU A 1 98  ? 40.31000 -12.52800 30.43600  1.000 26.71442  ? 95  LEU H HD21 1 
ATOM   1465 H HD22 . LEU A 1 98  ? 40.54200 -11.20700 31.28800  1.000 26.71442  ? 95  LEU H HD22 1 
ATOM   1466 H HD23 . LEU A 1 98  ? 41.56700 -12.41500 31.40000  1.000 26.71442  ? 95  LEU H HD23 1 
ATOM   1467 N N    . GLY A 1 99  ? 41.98200 -12.10800 36.60100  1.000 24.81856  ? 96  GLY H N    1 
ATOM   1468 C CA   . GLY A 1 99  ? 42.40900 -11.33600 37.75300  1.000 24.68663  ? 96  GLY H CA   1 
ATOM   1469 C C    . GLY A 1 99  ? 41.62600 -10.05400 37.93500  1.000 22.87515  ? 96  GLY H C    1 
ATOM   1470 O O    . GLY A 1 99  ? 42.20700 -8.97100  38.05800  1.000 25.30677  ? 96  GLY H O    1 
ATOM   1471 H H    . GLY A 1 99  ? 41.70800 -12.90200 36.78300  1.000 29.78584  ? 96  GLY H H    1 
ATOM   1472 H HA2  . GLY A 1 99  ? 42.30000 -11.87300 38.55300  1.000 29.62753  ? 96  GLY H HA2  1 
ATOM   1473 H HA3  . GLY A 1 99  ? 43.34600 -11.10700 37.65200  1.000 29.62753  ? 96  GLY H HA3  1 
ATOM   1474 N N    . THR A 1 100 ? 40.29800 -10.16000 37.95000  1.000 25.25797  ? 97  THR H N    1 
ATOM   1475 C CA   . THR A 1 100 ? 39.47100 -8.97800  38.13700  1.000 25.81830  ? 97  THR H CA   1 
ATOM   1476 C C    . THR A 1 100 ? 39.48300 -8.50400  39.58400  1.000 25.95756  ? 97  THR H C    1 
ATOM   1477 O O    . THR A 1 100 ? 39.37000 -7.30000  39.83600  1.000 25.17776  ? 97  THR H O    1 
ATOM   1478 C CB   . THR A 1 100 ? 38.03300 -9.26100  37.69800  1.000 26.14928  ? 97  THR H CB   1 
ATOM   1479 O OG1  . THR A 1 100 ? 37.52700 -10.39000 38.41800  1.000 23.64665  ? 97  THR H OG1  1 
ATOM   1480 C CG2  . THR A 1 100 ? 37.96300 -9.54200  36.19600  1.000 22.80760  ? 97  THR H CG2  1 
ATOM   1481 H H    . THR A 1 100 ? 39.86200 -10.89500 37.85600  1.000 30.31314  ? 97  THR H H    1 
ATOM   1482 H HA   . THR A 1 100 ? 39.81900 -8.26600  37.57700  1.000 30.98552  ? 97  THR H HA   1 
ATOM   1483 H HB   . THR A 1 100 ? 37.48300 -8.48300  37.88400  1.000 31.38270  ? 97  THR H HB   1 
ATOM   1484 H HG1  . THR A 1 100 ? 37.99600 -11.06800 38.25500  1.000 28.37955  ? 97  THR H HG1  1 
ATOM   1485 H HG21 . THR A 1 100 ? 37.04700 -9.72400  35.93500  1.000 27.37269  ? 97  THR H HG21 1 
ATOM   1486 H HG22 . THR A 1 100 ? 38.28600 -8.77300  35.70000  1.000 27.37269  ? 97  THR H HG22 1 
ATOM   1487 H HG23 . THR A 1 100 ? 38.51200 -10.31100 35.97700  1.000 27.37269  ? 97  THR H HG23 1 
ATOM   1488 N N    . GLY A 1 101 ? 39.62700 -9.42400  40.53600  1.000 28.10766  ? 98  GLY H N    1 
ATOM   1489 C CA   . GLY A 1 101 ? 39.61400 -9.06800  41.94200  1.000 31.98877  ? 98  GLY H CA   1 
ATOM   1490 C C    . GLY A 1 101 ? 40.81100 -9.57700  42.71900  1.000 33.43838  ? 98  GLY H C    1 
ATOM   1491 O O    . GLY A 1 101 ? 40.97700 -9.25200  43.89900  1.000 38.10834  ? 98  GLY H O    1 
ATOM   1492 H H    . GLY A 1 101 ? 39.73300 -10.26400 40.38800  1.000 33.73276  ? 98  GLY H H    1 
ATOM   1493 H HA2  . GLY A 1 101 ? 39.59600 -8.10200  42.02100  1.000 38.39009  ? 98  GLY H HA2  1 
ATOM   1494 H HA3  . GLY A 1 101 ? 38.81500 -9.43400  42.35100  1.000 38.39009  ? 98  GLY H HA3  1 
ATOM   1495 N N    . SER A 1 102 ? 41.65400 -10.37100 42.07000  1.000 33.46865  ? 99  SER H N    1 
ATOM   1496 C CA   . SER A 1 102 ? 42.83300 -10.95700 42.68500  1.000 30.68681  ? 99  SER H CA   1 
ATOM   1497 C C    . SER A 1 102 ? 44.09500 -10.35400 42.08500  1.000 34.75911  ? 99  SER H C    1 
ATOM   1498 O O    . SER A 1 102 ? 44.07300 -9.70800  41.03300  1.000 34.30859  ? 99  SER H O    1 
ATOM   1499 C CB   . SER A 1 102 ? 42.83800 -12.47700 42.49800  1.000 34.56871  ? 99  SER H CB   1 
ATOM   1500 O OG   . SER A 1 102 ? 42.71000 -12.80700 41.12700  1.000 38.54999  ? 99  SER H OG   1 
ATOM   1501 H H    . SER A 1 102 ? 41.55800 -10.59100 41.24400  1.000 40.16595  ? 99  SER H H    1 
ATOM   1502 H HA   . SER A 1 102 ? 42.82500 -10.76300 43.63600  1.000 36.82774  ? 99  SER H HA   1 
ATOM   1503 H HB2  . SER A 1 102 ? 43.67400 -12.83600 42.83500  1.000 41.48603  ? 99  SER H HB2  1 
ATOM   1504 H HB3  . SER A 1 102 ? 42.09200 -12.85900 42.98800  1.000 41.48603  ? 99  SER H HB3  1 
ATOM   1505 H HG   . SER A 1 102 ? 41.97700 -12.52300 40.83000  1.000 46.26355  ? 99  SER H HG   1 
ATOM   1506 N N    . ARG A 1 103 ? 45.21400 -10.58200 42.76800  1.000 31.32663  ? 100 ARG H N    1 
ATOM   1507 C CA   . ARG A 1 103 ? 46.48400 -10.06400 42.28100  1.000 35.08791  ? 100 ARG H CA   1 
ATOM   1508 C C    . ARG A 1 103 ? 47.10200 -10.95200 41.20800  1.000 33.39881  ? 100 ARG H C    1 
ATOM   1509 O O    . ARG A 1 103 ? 47.93600 -10.47100 40.43300  1.000 31.62725  ? 100 ARG H O    1 
ATOM   1510 C CB   . ARG A 1 103 ? 47.45900 -9.89000  43.44700  1.000 40.15866  ? 100 ARG H CB   1 
ATOM   1511 C CG   . ARG A 1 103 ? 48.75500 -9.20300  43.04500  1.000 49.92818  ? 100 ARG H CG   1 
ATOM   1512 C CD   . ARG A 1 103 ? 49.60300 -8.81100  44.24500  1.000 52.37842  ? 100 ARG H CD   1 
ATOM   1513 N NE   . ARG A 1 103 ? 50.85000 -8.17500  43.83100  1.000 61.23805  ? 100 ARG H NE   1 
ATOM   1514 C CZ   . ARG A 1 103 ? 50.96500 -6.90200  43.47600  1.000 64.24804  ? 100 ARG H CZ   1 
ATOM   1515 N NH1  . ARG A 1 103 ? 49.92400 -6.08500  43.47900  1.000 60.27854  ? 100 ARG H NH1  1 
ATOM   1516 N NH2  . ARG A 1 103 ? 52.15400 -6.43700  43.10300  1.000 56.78862  ? 100 ARG H NH2  1 
ATOM   1517 H H    . ARG A 1 103 ? 45.26100 -11.02600 43.50300  1.000 37.59552  ? 100 ARG H H    1 
ATOM   1518 H HA   . ARG A 1 103 ? 46.33800 -9.18900  41.88900  1.000 42.10907  ? 100 ARG H HA   1 
ATOM   1519 H HB2  . ARG A 1 103 ? 47.03600 -9.35100  44.13300  1.000 48.19396  ? 100 ARG H HB2  1 
ATOM   1520 H HB3  . ARG A 1 103 ? 47.68300 -10.76400 43.80300  1.000 48.19396  ? 100 ARG H HB3  1 
ATOM   1521 H HG2  . ARG A 1 103 ? 49.27600 -9.80700  42.49300  1.000 59.91739  ? 100 ARG H HG2  1 
ATOM   1522 H HG3  . ARG A 1 103 ? 48.54500 -8.39700  42.54900  1.000 59.91739  ? 100 ARG H HG3  1 
ATOM   1523 H HD2  . ARG A 1 103 ? 49.11000 -8.18500  44.79700  1.000 62.85767  ? 100 ARG H HD2  1 
ATOM   1524 H HD3  . ARG A 1 103 ? 49.82100 -9.60500  44.75800  1.000 62.85767  ? 100 ARG H HD3  1 
ATOM   1525 H HE   . ARG A 1 103 ? 51.56100 -8.66000  43.81600  1.000 73.48923  ? 100 ARG H HE   1 
ATOM   1526 H HH11 . ARG A 1 103 ? 49.15000 -6.37600  43.71500  1.000 72.33781  ? 100 ARG H HH11 1 
ATOM   1527 H HH12 . ARG A 1 103 ? 50.02100 -5.26300  43.24500  1.000 72.33781  ? 100 ARG H HH12 1 
ATOM   1528 H HH21 . ARG A 1 103 ? 52.83700 -6.96000  43.09400  1.000 68.14992  ? 100 ARG H HH21 1 
ATOM   1529 H HH22 . ARG A 1 103 ? 52.24100 -5.61300  42.87100  1.000 68.14992  ? 100 ARG H HH22 1 
ATOM   1530 N N    . PHE A 1 104 A 46.70300 -12.21800 41.12600  1.000 28.66619  ? 100 PHE H N    1 
ATOM   1531 C CA   . PHE A 1 104 A 47.28300 -13.15400 40.17000  1.000 31.60903  ? 100 PHE H CA   1 
ATOM   1532 C C    . PHE A 1 104 A 46.49500 -13.08900 38.86700  1.000 29.61692  ? 100 PHE H C    1 
ATOM   1533 O O    . PHE A 1 104 A 45.30000 -13.40400 38.84100  1.000 27.48594  ? 100 PHE H O    1 
ATOM   1534 C CB   . PHE A 1 104 A 47.28600 -14.57100 40.74400  1.000 30.16813  ? 100 PHE H CB   1 
ATOM   1535 C CG   . PHE A 1 104 A 47.88300 -15.60500 39.82600  1.000 32.15862  ? 100 PHE H CG   1 
ATOM   1536 C CD1  . PHE A 1 104 A 48.99400 -15.31300 39.04900  1.000 33.29987  ? 100 PHE H CD1  1 
ATOM   1537 C CD2  . PHE A 1 104 A 47.34100 -16.87800 39.75600  1.000 34.80800  ? 100 PHE H CD2  1 
ATOM   1538 C CE1  . PHE A 1 104 A 49.54200 -16.26600 38.21100  1.000 29.22764  ? 100 PHE H CE1  1 
ATOM   1539 C CE2  . PHE A 1 104 A 47.88600 -17.83500 38.92100  1.000 35.74887  ? 100 PHE H CE2  1 
ATOM   1540 C CZ   . PHE A 1 104 A 48.98700 -17.52900 38.14700  1.000 32.55831  ? 100 PHE H CZ   1 
ATOM   1541 H H    . PHE A 1 104 A 46.09000 -12.56300 41.62100  1.000 34.40300  ? 100 PHE H H    1 
ATOM   1542 H HA   . PHE A 1 104 A 48.20000 -12.90400 39.98000  1.000 37.93440  ? 100 PHE H HA   1 
ATOM   1543 H HB2  . PHE A 1 104 A 47.80200 -14.57200 41.56500  1.000 36.20533  ? 100 PHE H HB2  1 
ATOM   1544 H HB3  . PHE A 1 104 A 46.37000 -14.83400 40.92800  1.000 36.20533  ? 100 PHE H HB3  1 
ATOM   1545 H HD1  . PHE A 1 104 A 49.37600 -14.46600 39.09200  1.000 39.96342  ? 100 PHE H HD1  1 
ATOM   1546 H HD2  . PHE A 1 104 A 46.60100 -17.09100 40.27700  1.000 41.77317  ? 100 PHE H HD2  1 
ATOM   1547 H HE1  . PHE A 1 104 A 50.28400 -16.05700 37.69000  1.000 35.07674  ? 100 PHE H HE1  1 
ATOM   1548 H HE2  . PHE A 1 104 A 47.51000 -18.68500 38.88000  1.000 42.90221  ? 100 PHE H HE2  1 
ATOM   1549 H HZ   . PHE A 1 104 A 49.35400 -18.17200 37.58500  1.000 39.07355  ? 100 PHE H HZ   1 
ATOM   1550 N N    . ALA A 1 105 ? 47.16300 -12.66500 37.79400  1.000 31.13837  ? 101 ALA H N    1 
ATOM   1551 C CA   . ALA A 1 105 ? 46.58900 -12.64000 36.45500  1.000 27.57690  ? 101 ALA H CA   1 
ATOM   1552 C C    . ALA A 1 105 ? 47.62600 -13.16900 35.47500  1.000 27.83734  ? 101 ALA H C    1 
ATOM   1553 O O    . ALA A 1 105 ? 48.80700 -12.82400 35.56900  1.000 27.45733  ? 101 ALA H O    1 
ATOM   1554 C CB   . ALA A 1 105 ? 46.15400 -11.22500 36.05100  1.000 27.06823  ? 101 ALA H CB   1 
ATOM   1555 H H    . ALA A 1 105 ? 47.97300 -12.37900 37.82000  1.000 37.36962  ? 101 ALA H H    1 
ATOM   1556 H HA   . ALA A 1 105 ? 45.80500 -13.21000 36.41900  1.000 33.09585  ? 101 ALA H HA   1 
ATOM   1557 H HB1  . ALA A 1 105 ? 45.76300 -11.25500 35.16400  1.000 32.48545  ? 101 ALA H HB1  1 
ATOM   1558 H HB2  . ALA A 1 105 ? 45.49900 -10.90100 36.69000  1.000 32.48545  ? 101 ALA H HB2  1 
ATOM   1559 H HB3  . ALA A 1 105 ? 46.93100 -10.64300 36.05100  1.000 32.48545  ? 101 ALA H HB3  1 
ATOM   1560 N N    . ILE A 1 106 ? 47.18300 -14.00400 34.53800  1.000 28.60834  ? 102 ILE H N    1 
ATOM   1561 C CA   . ILE A 1 106 ? 48.07800 -14.61500 33.55800  1.000 29.03853  ? 102 ILE H CA   1 
ATOM   1562 C C    . ILE A 1 106 ? 47.29400 -14.87300 32.27900  1.000 26.47749  ? 102 ILE H C    1 
ATOM   1563 O O    . ILE A 1 106 ? 46.15800 -15.35400 32.31900  1.000 25.29761  ? 102 ILE H O    1 
ATOM   1564 C CB   . ILE A 1 106 ? 48.70400 -15.91500 34.11400  1.000 29.52786  ? 102 ILE H CB   1 
ATOM   1565 C CG1  . ILE A 1 106 ? 49.75000 -16.47900 33.15100  1.000 32.62921  ? 102 ILE H CG1  1 
ATOM   1566 C CG2  . ILE A 1 106 ? 47.62600 -16.95300 34.40000  1.000 30.38794  ? 102 ILE H CG2  1 
ATOM   1567 C CD1  . ILE A 1 106 ? 51.16300 -16.07700 33.49900  1.000 37.62923  ? 102 ILE H CD1  1 
ATOM   1568 H H    . ILE A 1 106 ? 46.36000 -14.23500 34.44700  1.000 34.33358  ? 102 ILE H H    1 
ATOM   1569 H HA   . ILE A 1 106 ? 48.79500 -13.99700 33.34600  1.000 34.84981  ? 102 ILE H HA   1 
ATOM   1570 H HB   . ILE A 1 106 ? 49.14900 -15.69500 34.94700  1.000 35.43701  ? 102 ILE H HB   1 
ATOM   1571 H HG12 . ILE A 1 106 ? 49.70200 -17.44700 33.16900  1.000 39.15862  ? 102 ILE H HG12 1 
ATOM   1572 H HG13 . ILE A 1 106 ? 49.55900 -16.15400 32.25700  1.000 39.15862  ? 102 ILE H HG13 1 
ATOM   1573 H HG21 . ILE A 1 106 ? 48.04100 -17.74300 34.78000  1.000 36.46910  ? 102 ILE H HG21 1 
ATOM   1574 H HG22 . ILE A 1 106 ? 46.98700 -16.58000 35.02800  1.000 36.46910  ? 102 ILE H HG22 1 
ATOM   1575 H HG23 . ILE A 1 106 ? 47.17900 -17.18100 33.57000  1.000 36.46910  ? 102 ILE H HG23 1 
ATOM   1576 H HD11 . ILE A 1 106 ? 51.76500 -16.41800 32.81800  1.000 45.15864  ? 102 ILE H HD11 1 
ATOM   1577 H HD12 . ILE A 1 106 ? 51.21700 -15.10900 33.53400  1.000 45.15864  ? 102 ILE H HD12 1 
ATOM   1578 H HD13 . ILE A 1 106 ? 51.39500 -16.45300 34.36200  1.000 45.15864  ? 102 ILE H HD13 1 
ATOM   1579 N N    . TRP A 1 107 ? 47.91600 -14.55900 31.14100  1.000 28.35923  ? 103 TRP H N    1 
ATOM   1580 C CA   . TRP A 1 107 ? 47.33200 -14.75800 29.82200  1.000 25.85801  ? 103 TRP H CA   1 
ATOM   1581 C C    . TRP A 1 107 ? 48.25300 -15.61600 28.96500  1.000 27.55841  ? 103 TRP H C    1 
ATOM   1582 O O    . TRP A 1 107 ? 49.47500 -15.43900 28.98700  1.000 26.98764  ? 103 TRP H O    1 
ATOM   1583 C CB   . TRP A 1 107 ? 47.11000 -13.42400 29.09500  1.000 24.07738  ? 103 TRP H CB   1 
ATOM   1584 C CG   . TRP A 1 107 ? 45.93800 -12.62900 29.55100  1.000 24.92829  ? 103 TRP H CG   1 
ATOM   1585 C CD1  . TRP A 1 107 ? 45.70700 -12.15200 30.81000  1.000 25.40854  ? 103 TRP H CD1  1 
ATOM   1586 C CD2  . TRP A 1 107 ? 44.84100 -12.18600 28.74500  1.000 22.65770  ? 103 TRP H CD2  1 
ATOM   1587 N NE1  . TRP A 1 107 ? 44.52500 -11.45100 30.83800  1.000 24.20841  ? 103 TRP H NE1  1 
ATOM   1588 C CE2  . TRP A 1 107 ? 43.97500 -11.45700 29.58300  1.000 23.67867  ? 103 TRP H CE2  1 
ATOM   1589 C CE3  . TRP A 1 107 ? 44.50300 -12.34100 27.39700  1.000 21.84780  ? 103 TRP H CE3  1 
ATOM   1590 C CZ2  . TRP A 1 107 ? 42.79300 -10.88400 29.11600  1.000 20.86740  ? 103 TRP H CZ2  1 
ATOM   1591 C CZ3  . TRP A 1 107 ? 43.32900 -11.77300 26.93700  1.000 20.00720  ? 103 TRP H CZ3  1 
ATOM   1592 C CH2  . TRP A 1 107 ? 42.49000 -11.05400 27.79200  1.000 22.24857  ? 103 TRP H CH2  1 
ATOM   1593 H H    . TRP A 1 107 ? 48.70500 -14.21600 31.11100  1.000 34.03464  ? 103 TRP H H    1 
ATOM   1594 H HA   . TRP A 1 107 ? 46.48100 -15.21000 29.93300  1.000 31.03318  ? 103 TRP H HA   1 
ATOM   1595 H HB2  . TRP A 1 107 ? 47.89800 -12.87300 29.22100  1.000 28.89642  ? 103 TRP H HB2  1 
ATOM   1596 H HB3  . TRP A 1 107 ? 46.98200 -13.60900 28.15100  1.000 28.89642  ? 103 TRP H HB3  1 
ATOM   1597 H HD1  . TRP A 1 107 ? 46.26700 -12.28300 31.54000  1.000 30.49382  ? 103 TRP H HD1  1 
ATOM   1598 H HE1  . TRP A 1 107 ? 44.18600 -11.07100 31.53100  1.000 29.05366  ? 103 TRP H HE1  1 
ATOM   1599 H HE3  . TRP A 1 107 ? 45.05600 -12.81800 26.82200  1.000 26.22093  ? 103 TRP H HE3  1 
ATOM   1600 H HZ2  . TRP A 1 107 ? 42.23200 -10.40500 29.68200  1.000 25.04446  ? 103 TRP H HZ2  1 
ATOM   1601 H HZ3  . TRP A 1 107 ? 43.09500 -11.87100 26.04300  1.000 24.01221  ? 103 TRP H HZ3  1 
ATOM   1602 H HH2  . TRP A 1 107 ? 41.70700 -10.68200 27.45400  1.000 26.70185  ? 103 TRP H HH2  1 
ATOM   1603 N N    . GLY A 1 108 ? 47.66500 -16.52800 28.19800  1.000 26.45733  ? 104 GLY H N    1 
ATOM   1604 C CA   . GLY A 1 108 ? 48.39200 -17.17200 27.12000  1.000 28.14866  ? 104 GLY H CA   1 
ATOM   1605 C C    . GLY A 1 108 ? 48.77900 -16.16800 26.04800  1.000 24.96769  ? 104 GLY H C    1 
ATOM   1606 O O    . GLY A 1 108 ? 48.32400 -15.02600 26.02500  1.000 23.08738  ? 104 GLY H O    1 
ATOM   1607 H H    . GLY A 1 108 ? 46.84900 -16.78800 28.28300  1.000 31.75237  ? 104 GLY H H    1 
ATOM   1608 H HA2  . GLY A 1 108 ? 49.19900 -17.58100 27.47000  1.000 33.78196  ? 104 GLY H HA2  1 
ATOM   1609 H HA3  . GLY A 1 108 ? 47.83900 -17.86000 26.71800  1.000 33.78196  ? 104 GLY H HA3  1 
ATOM   1610 N N    . GLN A 1 109 ? 49.65300 -16.60300 25.13800  1.000 25.34756  ? 105 GLN H N    1 
ATOM   1611 C CA   . GLN A 1 109 ? 50.17500 -15.66600 24.14800  1.000 26.63871  ? 105 GLN H CA   1 
ATOM   1612 C C    . GLN A 1 109 ? 49.16000 -15.32600 23.06200  1.000 23.84723  ? 105 GLN H C    1 
ATOM   1613 O O    . GLN A 1 109 ? 49.38000 -14.37000 22.31100  1.000 26.24825  ? 105 GLN H O    1 
ATOM   1614 C CB   . GLN A 1 109 ? 51.45900 -16.21800 23.51100  1.000 30.28047  ? 105 GLN H CB   1 
ATOM   1615 C CG   . GLN A 1 109 ? 51.27100 -17.30300 22.45200  1.000 25.86784  ? 105 GLN H CG   1 
ATOM   1616 C CD   . GLN A 1 109 ? 51.05300 -18.69200 23.03100  1.000 29.00836  ? 105 GLN H CD   1 
ATOM   1617 O OE1  . GLN A 1 109 ? 50.83500 -18.85700 24.23200  1.000 32.25888  ? 105 GLN H OE1  1 
ATOM   1618 N NE2  . GLN A 1 109 ? 51.11300 -19.70100 22.17000  1.000 28.87902  ? 105 GLN H NE2  1 
ATOM   1619 H H    . GLN A 1 109 ? 49.94900 -17.40900 25.07600  1.000 30.42065  ? 105 GLN H H    1 
ATOM   1620 H HA   . GLN A 1 109 ? 50.40800 -14.84100 24.60100  1.000 31.97002  ? 105 GLN H HA   1 
ATOM   1621 H HB2  . GLN A 1 109 ? 51.92700 -15.48200 23.08700  1.000 36.34013  ? 105 GLN H HB2  1 
ATOM   1622 H HB3  . GLN A 1 109 ? 52.00700 -16.59800 24.21600  1.000 36.34013  ? 105 GLN H HB3  1 
ATOM   1623 H HG2  . GLN A 1 109 ? 50.49500 -17.08200 21.91300  1.000 31.04498  ? 105 GLN H HG2  1 
ATOM   1624 H HG3  . GLN A 1 109 ? 52.06400 -17.33500 21.89500  1.000 31.04498  ? 105 GLN H HG3  1 
ATOM   1625 H HE21 . GLN A 1 109 ? 51.26800 -19.54800 21.33800  1.000 34.65840  ? 105 GLN H HE21 1 
ATOM   1626 H HE22 . GLN A 1 109 ? 50.99700 -20.50800 22.44500  1.000 34.65840  ? 105 GLN H HE22 1 
ATOM   1627 N N    . GLY A 1 110 ? 48.06700 -16.07900 22.96200  1.000 25.51861  ? 106 GLY H N    1 
ATOM   1628 C CA   . GLY A 1 110 ? 47.07700 -15.85700 21.92900  1.000 23.82815  ? 106 GLY H CA   1 
ATOM   1629 C C    . GLY A 1 110 ? 47.36300 -16.66700 20.68100  1.000 24.48880  ? 106 GLY H C    1 
ATOM   1630 O O    . GLY A 1 110 ? 48.52200 -16.80300 20.28200  1.000 23.81677  ? 106 GLY H O    1 
ATOM   1631 H H    . GLY A 1 110 ? 47.87900 -16.73100 23.49000  1.000 30.62591  ? 106 GLY H H    1 
ATOM   1632 H HA2  . GLY A 1 110 ? 46.20100 -16.10600 22.26300  1.000 28.59735  ? 106 GLY H HA2  1 
ATOM   1633 H HA3  . GLY A 1 110 ? 47.06700 -14.91700 21.68800  1.000 28.59735  ? 106 GLY H HA3  1 
ATOM   1634 N N    . THR A 1 111 ? 46.31600 -17.21200 20.06000  1.000 21.22704  ? 107 THR H N    1 
ATOM   1635 C CA   . THR A 1 111 ? 46.44500 -18.03300 18.86000  1.000 21.93711  ? 107 THR H CA   1 
ATOM   1636 C C    . THR A 1 111 ? 45.36200 -17.62100 17.87400  1.000 18.94684  ? 107 THR H C    1 
ATOM   1637 O O    . THR A 1 111 ? 44.17400 -17.65800 18.20700  1.000 19.43815  ? 107 THR H O    1 
ATOM   1638 C CB   . THR A 1 111 ? 46.31500 -19.52600 19.18900  1.000 23.50749  ? 107 THR H CB   1 
ATOM   1639 O OG1  . THR A 1 111 ? 47.35500 -19.91900 20.09300  1.000 30.11030  ? 107 THR H OG1  1 
ATOM   1640 C CG2  . THR A 1 111 ? 46.39900 -20.37200 17.92500  1.000 27.09947  ? 107 THR H CG2  1 
ATOM   1641 H H    . THR A 1 111 ? 45.50300 -17.11800 20.32200  1.000 25.47601  ? 107 THR H H    1 
ATOM   1642 H HA   . THR A 1 111 ? 47.31300 -17.87800 18.45700  1.000 26.32810  ? 107 THR H HA   1 
ATOM   1643 H HB   . THR A 1 111 ? 45.45200 -19.68400 19.60200  1.000 28.21255  ? 107 THR H HB   1 
ATOM   1644 H HG1  . THR A 1 111 ? 47.30900 -20.74400 20.24200  1.000 36.13593  ? 107 THR H HG1  1 
ATOM   1645 H HG21 . THR A 1 111 ? 46.41700 -21.31400 18.15700  1.000 32.52294  ? 107 THR H HG21 1 
ATOM   1646 H HG22 . THR A 1 111 ? 45.63000 -20.20100 17.35900  1.000 32.52294  ? 107 THR H HG22 1 
ATOM   1647 H HG23 . THR A 1 111 ? 47.20600 -20.15400 17.43300  1.000 32.52294  ? 107 THR H HG23 1 
ATOM   1648 N N    . LEU A 1 112 ? 45.76600 -17.23800 16.66700  1.000 20.39670  ? 108 LEU H N    1 
ATOM   1649 C CA   . LEU A 1 112 ? 44.80900 -16.89700 15.62700  1.000 19.26809  ? 108 LEU H CA   1 
ATOM   1650 C C    . LEU A 1 112 ? 44.20200 -18.17200 15.05300  1.000 18.85740  ? 108 LEU H C    1 
ATOM   1651 O O    . LEU A 1 112 ? 44.92500 -19.07300 14.62200  1.000 22.42834  ? 108 LEU H O    1 
ATOM   1652 C CB   . LEU A 1 112 ? 45.49000 -16.09000 14.51800  1.000 20.04796  ? 108 LEU H CB   1 
ATOM   1653 C CG   . LEU A 1 112 ? 44.60300 -15.65600 13.35000  1.000 19.94864  ? 108 LEU H CG   1 
ATOM   1654 C CD1  . LEU A 1 112 ? 43.49800 -14.71800 13.80900  1.000 20.62915  ? 108 LEU H CD1  1 
ATOM   1655 C CD2  . LEU A 1 112 ? 45.42600 -14.99400 12.24600  1.000 21.62967  ? 108 LEU H CD2  1 
ATOM   1656 H H    . LEU A 1 112 ? 46.59000 -17.16800 16.42800  1.000 24.47961  ? 108 LEU H H    1 
ATOM   1657 H HA   . LEU A 1 112 ? 44.09800 -16.35400 16.00200  1.000 23.12528  ? 108 LEU H HA   1 
ATOM   1658 H HB2  . LEU A 1 112 ? 45.85600 -15.28300 14.91400  1.000 24.06113  ? 108 LEU H HB2  1 
ATOM   1659 H HB3  . LEU A 1 112 ? 46.20500 -16.63100 14.14800  1.000 24.06113  ? 108 LEU H HB3  1 
ATOM   1660 H HG   . LEU A 1 112 ? 44.18700 -16.45200 12.98400  1.000 23.94194  ? 108 LEU H HG   1 
ATOM   1661 H HD11 . LEU A 1 112 ? 42.97600 -14.44400 13.03800  1.000 24.75855  ? 108 LEU H HD11 1 
ATOM   1662 H HD12 . LEU A 1 112 ? 42.93200 -15.18400 14.44300  1.000 24.75855  ? 108 LEU H HD12 1 
ATOM   1663 H HD13 . LEU A 1 112 ? 43.89800 -13.94100 14.23000  1.000 24.75855  ? 108 LEU H HD13 1 
ATOM   1664 H HD21 . LEU A 1 112 ? 44.83300 -14.72900 11.52500  1.000 25.95918  ? 108 LEU H HD21 1 
ATOM   1665 H HD22 . LEU A 1 112 ? 45.87200 -14.21300 12.61000  1.000 25.95918  ? 108 LEU H HD22 1 
ATOM   1666 H HD23 . LEU A 1 112 ? 46.08300 -15.62800 11.91900  1.000 25.95918  ? 108 LEU H HD23 1 
ATOM   1667 N N    . VAL A 1 113 ? 42.87400 -18.24700 15.05800  1.000 15.31483  ? 109 VAL H N    1 
ATOM   1668 C CA   . VAL A 1 113 ? 42.13000 -19.31500 14.39700  1.000 18.51639  ? 109 VAL H CA   1 
ATOM   1669 C C    . VAL A 1 113 ? 41.42200 -18.70000 13.20000  1.000 19.57901  ? 109 VAL H C    1 
ATOM   1670 O O    . VAL A 1 113 ? 40.59200 -17.79600 13.36100  1.000 16.54639  ? 109 VAL H O    1 
ATOM   1671 C CB   . VAL A 1 113 ? 41.12500 -19.98000 15.35000  1.000 21.11948  ? 109 VAL H CB   1 
ATOM   1672 C CG1  . VAL A 1 113 ? 40.17500 -20.89700 14.58500  1.000 21.72896  ? 109 VAL H CG1  1 
ATOM   1673 C CG2  . VAL A 1 113 ? 41.86500 -20.74500 16.43400  1.000 20.47744  ? 109 VAL H CG2  1 
ATOM   1674 H H    . VAL A 1 113 ? 42.36700 -17.67300 15.44900  1.000 18.38137  ? 109 VAL H H    1 
ATOM   1675 H HA   . VAL A 1 113 ? 42.74500 -19.99500 14.08200  1.000 22.22324  ? 109 VAL H HA   1 
ATOM   1676 H HB   . VAL A 1 113 ? 40.58800 -19.29300 15.77400  1.000 25.34695  ? 109 VAL H HB   1 
ATOM   1677 H HG11 . VAL A 1 113 ? 39.67300 -21.43100 15.21900  1.000 26.07832  ? 109 VAL H HG11 1 
ATOM   1678 H HG12 . VAL A 1 113 ? 39.56900 -20.35300 14.05700  1.000 26.07832  ? 109 VAL H HG12 1 
ATOM   1679 H HG13 . VAL A 1 113 ? 40.69400 -21.47400 14.00300  1.000 26.07832  ? 109 VAL H HG13 1 
ATOM   1680 H HG21 . VAL A 1 113 ? 41.21700 -21.17500 17.01500  1.000 24.57650  ? 109 VAL H HG21 1 
ATOM   1681 H HG22 . VAL A 1 113 ? 42.43100 -21.41500 16.01800  1.000 24.57650  ? 109 VAL H HG22 1 
ATOM   1682 H HG23 . VAL A 1 113 ? 42.40700 -20.12400 16.94500  1.000 24.57650  ? 109 VAL H HG23 1 
ATOM   1683 N N    . THR A 1 114 ? 41.74500 -19.17800 12.00300  1.000 17.87621  ? 110 THR H N    1 
ATOM   1684 C CA   . THR A 1 114 ? 41.11900 -18.70700 10.77600  1.000 17.93719  ? 110 THR H CA   1 
ATOM   1685 C C    . THR A 1 114 ? 40.13900 -19.76100 10.28800  1.000 18.92744  ? 110 THR H C    1 
ATOM   1686 O O    . THR A 1 114 ? 40.50900 -20.92800 10.12900  1.000 19.36823  ? 110 THR H O    1 
ATOM   1687 C CB   . THR A 1 114 ? 42.16300 -18.41900 9.69400   1.000 18.79759  ? 110 THR H CB   1 
ATOM   1688 O OG1  . THR A 1 114 ? 43.11100 -17.46100 10.18100  1.000 19.95891  ? 110 THR H OG1  1 
ATOM   1689 C CG2  . THR A 1 114 ? 41.49800 -17.86900 8.44400   1.000 20.16959  ? 110 THR H CG2  1 
ATOM   1690 H H    . THR A 1 114 ? 42.33700 -19.78800 11.87600  1.000 21.45502  ? 110 THR H H    1 
ATOM   1691 H HA   . THR A 1 114 ? 40.63600 -17.88400 10.95200  1.000 21.52819  ? 110 THR H HA   1 
ATOM   1692 H HB   . THR A 1 114 ? 42.62100 -19.24200 9.46400   1.000 22.56067  ? 110 THR H HB   1 
ATOM   1693 H HG1  . THR A 1 114 ? 43.87600 -17.63800 9.88300   1.000 23.95426  ? 110 THR H HG1  1 
ATOM   1694 H HG21 . THR A 1 114 ? 42.17100 -17.63100 7.78800   1.000 24.20707  ? 110 THR H HG21 1 
ATOM   1695 H HG22 . THR A 1 114 ? 40.90700 -18.53600 8.06200   1.000 24.20707  ? 110 THR H HG22 1 
ATOM   1696 H HG23 . THR A 1 114 ? 40.98000 -17.07900 8.66400   1.000 24.20707  ? 110 THR H HG23 1 
ATOM   1697 N N    . VAL A 1 115 ? 38.89800 -19.35500 10.05300  1.000 18.00755  ? 111 VAL H N    1 
ATOM   1698 C CA   . VAL A 1 115 ? 37.86900 -20.24400 9.52900   1.000 16.86563  ? 111 VAL H CA   1 
ATOM   1699 C C    . VAL A 1 115 ? 37.77800 -20.00300 8.02800   1.000 20.44924  ? 111 VAL H C    1 
ATOM   1700 O O    . VAL A 1 115 ? 37.26200 -18.97300 7.57800   1.000 20.18816  ? 111 VAL H O    1 
ATOM   1701 C CB   . VAL A 1 115 ? 36.52000 -20.02300 10.22300  1.000 22.25867  ? 111 VAL H CB   1 
ATOM   1702 C CG1  . VAL A 1 115 ? 35.48400 -20.98900 9.68500   1.000 21.78765  ? 111 VAL H CG1  1 
ATOM   1703 C CG2  . VAL A 1 115 ? 36.67500 -20.20200 11.72900  1.000 19.34690  ? 111 VAL H CG2  1 
ATOM   1704 H H    . VAL A 1 115 ? 38.62200 -18.55200 10.19200  1.000 21.61263  ? 111 VAL H H    1 
ATOM   1705 H HA   . VAL A 1 115 ? 38.13200 -21.16600 9.67400   1.000 20.24233  ? 111 VAL H HA   1 
ATOM   1706 H HB   . VAL A 1 115 ? 36.21500 -19.11900 10.04500  1.000 26.71398  ? 111 VAL H HB   1 
ATOM   1707 H HG11 . VAL A 1 115 ? 34.66900 -20.89900 10.20400  1.000 26.14875  ? 111 VAL H HG11 1 
ATOM   1708 H HG12 . VAL A 1 115 ? 35.30900 -20.77800 8.75500   1.000 26.14875  ? 111 VAL H HG12 1 
ATOM   1709 H HG13 . VAL A 1 115 ? 35.82700 -21.89300 9.76100   1.000 26.14875  ? 111 VAL H HG13 1 
ATOM   1710 H HG21 . VAL A 1 115 ? 35.80300 -20.13300 12.14600  1.000 23.21986  ? 111 VAL H HG21 1 
ATOM   1711 H HG22 . VAL A 1 115 ? 37.05900 -21.07500 11.90500  1.000 23.21986  ? 111 VAL H HG22 1 
ATOM   1712 H HG23 . VAL A 1 115 ? 37.26100 -19.50800 12.07000  1.000 23.21986  ? 111 VAL H HG23 1 
ATOM   1713 N N    . SER A 1 116 ? 38.29100 -20.95600 7.25400   1.000 16.96363  ? 112 SER H N    1 
ATOM   1714 C CA   . SER A 1 116 ? 38.28900 -20.84700 5.80400   1.000 18.24717  ? 112 SER H CA   1 
ATOM   1715 C C    . SER A 1 116 ? 38.44700 -22.23300 5.19700   1.000 20.26827  ? 112 SER H C    1 
ATOM   1716 O O    . SER A 1 116 ? 39.04700 -23.12500 5.80200   1.000 17.47414  ? 112 SER H O    1 
ATOM   1717 C CB   . SER A 1 116 ? 39.41200 -19.92900 5.31700   1.000 18.34632  ? 112 SER H CB   1 
ATOM   1718 O OG   . SER A 1 116 ? 39.50000 -19.95300 3.90700   1.000 22.30006  ? 112 SER H OG   1 
ATOM   1719 H H    . SER A 1 116 ? 38.64800 -21.68000 7.55000   1.000 20.35993  ? 112 SER H H    1 
ATOM   1720 H HA   . SER A 1 116 ? 37.43800 -20.48500 5.51200   1.000 21.90018  ? 112 SER H HA   1 
ATOM   1721 H HB2  . SER A 1 116 ? 39.22700 -19.02200 5.60700   1.000 22.01916  ? 112 SER H HB2  1 
ATOM   1722 H HB3  . SER A 1 116 ? 40.25400 -20.23200 5.69200   1.000 22.01916  ? 112 SER H HB3  1 
ATOM   1723 H HG   . SER A 1 116 ? 39.90500 -19.27100 3.63300   1.000 26.76364  ? 112 SER H HG   1 
ATOM   1724 N N    . SER A 1 117 ? 37.89400 -22.40100 4.00000   1.000 17.68562  ? 113 SER H N    1 
ATOM   1725 C CA   . SER A 1 117 ? 38.05800 -23.63000 3.23600   1.000 20.76849  ? 113 SER H CA   1 
ATOM   1726 C C    . SER A 1 117 ? 39.29700 -23.61400 2.35000   1.000 20.35803  ? 113 SER H C    1 
ATOM   1727 O O    . SER A 1 117 ? 39.57900 -24.61400 1.68300   1.000 18.39660  ? 113 SER H O    1 
ATOM   1728 C CB   . SER A 1 117 ? 36.82200 -23.88100 2.36800   1.000 21.77860  ? 113 SER H CB   1 
ATOM   1729 O OG   . SER A 1 117 ? 36.70100 -22.88600 1.37000   1.000 17.50741  ? 113 SER H OG   1 
ATOM   1730 H H    . SER A 1 117 ? 37.41300 -21.80800 3.60400   1.000 21.22632  ? 113 SER H H    1 
ATOM   1731 H HA   . SER A 1 117 ? 38.14300 -24.36900 3.85900   1.000 24.92576  ? 113 SER H HA   1 
ATOM   1732 H HB2  . SER A 1 117 ? 36.90600 -24.74800 1.94200   1.000 26.13789  ? 113 SER H HB2  1 
ATOM   1733 H HB3  . SER A 1 117 ? 36.03200 -23.86200 2.93100   1.000 26.13789  ? 113 SER H HB3  1 
ATOM   1734 H HG   . SER A 1 117 ? 36.62400 -22.12900 1.72600   1.000 21.01246  ? 113 SER H HG   1 
ATOM   1735 N N    . ALA A 1 118 ? 40.03700 -22.51400 2.31700   1.000 19.25845  ? 114 ALA H N    1 
ATOM   1736 C CA   . ALA A 1 118 ? 41.22600 -22.45700 1.48400   1.000 19.83877  ? 114 ALA H CA   1 
ATOM   1737 C C    . ALA A 1 118 ? 42.36200 -23.24500 2.12900   1.000 19.64865  ? 114 ALA H C    1 
ATOM   1738 O O    . ALA A 1 118 ? 42.33600 -23.56100 3.32200   1.000 19.84801  ? 114 ALA H O    1 
ATOM   1739 C CB   . ALA A 1 118 ? 41.64300 -21.00700 1.24800   1.000 19.88811  ? 114 ALA H CB   1 
ATOM   1740 H H    . ALA A 1 118 ? 39.87300 -21.79700 2.76300   1.000 23.11371  ? 114 ALA H H    1 
ATOM   1741 H HA   . ALA A 1 118 ? 41.04000 -22.85400 0.61900   1.000 23.81010  ? 114 ALA H HA   1 
ATOM   1742 H HB1  . ALA A 1 118 ? 42.44300 -20.99400 0.69900   1.000 23.86931  ? 114 ALA H HB1  1 
ATOM   1743 H HB2  . ALA A 1 118 ? 40.92300 -20.54100 0.79400   1.000 23.86931  ? 114 ALA H HB2  1 
ATOM   1744 H HB3  . ALA A 1 118 ? 41.82200 -20.58600 2.10300   1.000 23.86931  ? 114 ALA H HB3  1 
ATOM   1745 N N    . SER A 1 119 ? 43.36800 -23.56100 1.31900   1.000 19.05637  ? 115 SER H N    1 
ATOM   1746 C CA   . SER A 1 119 ? 44.50300 -24.35700 1.76100   1.000 19.85821  ? 115 SER H CA   1 
ATOM   1747 C C    . SER A 1 119 ? 45.65500 -23.46900 2.22500   1.000 18.50748  ? 115 SER H C    1 
ATOM   1748 O O    . SER A 1 119 ? 45.77400 -22.30500 1.83800   1.000 16.69661  ? 115 SER H O    1 
ATOM   1749 C CB   . SER A 1 119 ? 44.98000 -25.27300 0.63200   1.000 23.22855  ? 115 SER H CB   1 
ATOM   1750 O OG   . SER A 1 119 ? 43.98600 -26.22900 0.31100   1.000 26.92973  ? 115 SER H OG   1 
ATOM   1751 H H    . SER A 1 119 ? 43.41500 -23.32100 0.49500   1.000 22.87122  ? 115 SER H H    1 
ATOM   1752 H HA   . SER A 1 119 ? 44.22800 -24.90400 2.51300   1.000 23.83342  ? 115 SER H HA   1 
ATOM   1753 H HB2  . SER A 1 119 ? 45.16800 -24.73600 -0.15400  1.000 27.87783  ? 115 SER H HB2  1 
ATOM   1754 H HB3  . SER A 1 119 ? 45.78300 -25.73500 0.91800   1.000 27.87783  ? 115 SER H HB3  1 
ATOM   1755 H HG   . SER A 1 119 ? 43.24600 -25.84700 0.19700   1.000 32.31924  ? 115 SER H HG   1 
ATOM   1756 N N    . THR A 1 120 ? 46.51400 -24.04800 3.06300   1.000 16.39509  ? 116 THR H N    1 
ATOM   1757 C CA   . THR A 1 120 ? 47.71600 -23.35800 3.51100   1.000 17.96585  ? 116 THR H CA   1 
ATOM   1758 C C    . THR A 1 120 ? 48.68000 -23.16500 2.34600   1.000 23.38895  ? 116 THR H C    1 
ATOM   1759 O O    . THR A 1 120 ? 48.80000 -24.02300 1.46900   1.000 22.31456  ? 116 THR H O    1 
ATOM   1760 C CB   . THR A 1 120 ? 48.40000 -24.15300 4.62500   1.000 20.68633  ? 116 THR H CB   1 
ATOM   1761 O OG1  . THR A 1 120 ? 47.53000 -24.25200 5.75900   1.000 21.05929  ? 116 THR H OG1  1 
ATOM   1762 C CG2  . THR A 1 120 ? 49.69600 -23.48600 5.05300   1.000 20.38814  ? 116 THR H CG2  1 
ATOM   1763 H H    . THR A 1 120 ? 46.42100 -24.83900 3.38600   1.000 19.67768  ? 116 THR H H    1 
ATOM   1764 H HA   . THR A 1 120 ? 47.47600 -22.48600 3.86300   1.000 21.56259  ? 116 THR H HA   1 
ATOM   1765 H HB   . THR A 1 120 ? 48.60700 -25.04100 4.29300   1.000 24.82717  ? 116 THR H HB   1 
ATOM   1766 H HG1  . THR A 1 120 ? 46.87800 -24.74900 5.57900   1.000 25.27472  ? 116 THR H HG1  1 
ATOM   1767 H HG21 . THR A 1 120 ? 50.04600 -23.92000 5.84600   1.000 24.46933  ? 116 THR H HG21 1 
ATOM   1768 H HG22 . THR A 1 120 ? 50.35300 -23.55200 4.34200   1.000 24.46933  ? 116 THR H HG22 1 
ATOM   1769 H HG23 . THR A 1 120 ? 49.53800 -22.55000 5.25000   1.000 24.46933  ? 116 THR H HG23 1 
ATOM   1770 N N    . LYS A 1 121 ? 49.38100 -22.03300 2.35300   1.000 18.07697  ? 117 LYS H N    1 
ATOM   1771 C CA   . LYS A 1 121 ? 50.33200 -21.69700 1.29700   1.000 18.83565  ? 117 LYS H CA   1 
ATOM   1772 C C    . LYS A 1 121 ? 51.42100 -20.82600 1.90000   1.000 20.05961  ? 117 LYS H C    1 
ATOM   1773 O O    . LYS A 1 121 ? 51.12000 -19.78000 2.48100   1.000 14.40530  ? 117 LYS H O    1 
ATOM   1774 C CB   . LYS A 1 121 ? 49.63900 -20.96800 0.14500   1.000 22.00890  ? 117 LYS H CB   1 
ATOM   1775 C CG   . LYS A 1 121 ? 50.53400 -20.69000 -1.05400  1.000 22.88823  ? 117 LYS H CG   1 
ATOM   1776 C CD   . LYS A 1 121 ? 49.79700 -19.87800 -2.11000  1.000 21.65797  ? 117 LYS H CD   1 
ATOM   1777 C CE   . LYS A 1 121 ? 50.68100 -19.61200 -3.31400  1.000 24.72887  ? 117 LYS H CE   1 
ATOM   1778 N NZ   . LYS A 1 121 ? 51.94500 -18.93200 -2.91800  1.000 29.48038  ? 117 LYS H NZ   1 
ATOM   1779 H H    . LYS A 1 121 ? 49.32300 -21.43400 2.96700   1.000 21.69593  ? 117 LYS H H    1 
ATOM   1780 H HA   . LYS A 1 121 ? 50.73400 -22.50800 0.94800   1.000 22.60635  ? 117 LYS H HA   1 
ATOM   1781 H HB2  . LYS A 1 121 ? 48.89600 -21.51100 -0.16300  1.000 26.41426  ? 117 LYS H HB2  1 
ATOM   1782 H HB3  . LYS A 1 121 ? 49.31200 -20.11400 0.47100   1.000 26.41426  ? 117 LYS H HB3  1 
ATOM   1783 H HG2  . LYS A 1 121 ? 51.31100 -20.18600 -0.76600  1.000 27.46945  ? 117 LYS H HG2  1 
ATOM   1784 H HG3  . LYS A 1 121 ? 50.81100 -21.53000 -1.45100  1.000 27.46945  ? 117 LYS H HG3  1 
ATOM   1785 H HD2  . LYS A 1 121 ? 49.01500 -20.36900 -2.40700  1.000 25.99313  ? 117 LYS H HD2  1 
ATOM   1786 H HD3  . LYS A 1 121 ? 49.53000 -19.02500 -1.73200  1.000 25.99313  ? 117 LYS H HD3  1 
ATOM   1787 H HE2  . LYS A 1 121 ? 50.90700 -20.45400 -3.74000  1.000 29.67822  ? 117 LYS H HE2  1 
ATOM   1788 H HE3  . LYS A 1 121 ? 50.21000 -19.04000 -3.94000  1.000 29.67822  ? 117 LYS H HE3  1 
ATOM   1789 H HZ1  . LYS A 1 121 ? 52.32400 -18.55600 -3.63000  1.000 35.38002  ? 117 LYS H HZ1  1 
ATOM   1790 H HZ2  . LYS A 1 121 ? 51.77500 -18.30100 -2.31400  1.000 35.38002  ? 117 LYS H HZ2  1 
ATOM   1791 H HZ3  . LYS A 1 121 ? 52.51100 -19.52300 -2.56800  1.000 35.38002  ? 117 LYS H HZ3  1 
ATOM   1792 N N    . GLY A 1 122 ? 52.67400 -21.25500 1.77000   1.000 16.46693  ? 118 GLY H N    1 
ATOM   1793 C CA   . GLY A 1 122 ? 53.79200 -20.50700 2.29700   1.000 17.14805  ? 118 GLY H CA   1 
ATOM   1794 C C    . GLY A 1 122 ? 54.10400 -19.28100 1.46200   1.000 16.02640  ? 118 GLY H C    1 
ATOM   1795 O O    . GLY A 1 122 ? 53.72400 -19.18700 0.29200   1.000 17.25691  ? 118 GLY H O    1 
ATOM   1796 H H    . GLY A 1 122 ? 52.89800 -21.98500 1.37400   1.000 19.76388  ? 118 GLY H H    1 
ATOM   1797 H HA2  . GLY A 1 122 ? 53.59000 -20.22000 3.20100   1.000 20.58123  ? 118 GLY H HA2  1 
ATOM   1798 H HA3  . GLY A 1 122 ? 54.57900 -21.07400 2.31400   1.000 20.58123  ? 118 GLY H HA3  1 
ATOM   1799 N N    . PRO A 1 123 ? 54.81500 -18.32100 2.04400   1.000 17.32818  ? 119 PRO H N    1 
ATOM   1800 C CA   . PRO A 1 123 ? 55.02800 -17.03900 1.36900   1.000 16.55733  ? 119 PRO H CA   1 
ATOM   1801 C C    . PRO A 1 123 ? 56.22500 -17.03600 0.43100   1.000 17.17611  ? 119 PRO H C    1 
ATOM   1802 O O    . PRO A 1 123 ? 57.16400 -17.82400 0.55300   1.000 17.36787  ? 119 PRO H O    1 
ATOM   1803 C CB   . PRO A 1 123 ? 55.26900 -16.07300 2.54000   1.000 17.79875  ? 119 PRO H CB   1 
ATOM   1804 C CG   . PRO A 1 123 ? 55.95300 -16.92400 3.55800   1.000 19.07937  ? 119 PRO H CG   1 
ATOM   1805 C CD   . PRO A 1 123 ? 55.38700 -18.32700 3.40400   1.000 17.75852  ? 119 PRO H CD   1 
ATOM   1806 H HA   . PRO A 1 123 ? 54.23400 -16.78800 0.87100   1.000 19.87236  ? 119 PRO H HA   1 
ATOM   1807 H HB2  . PRO A 1 123 ? 55.83500 -15.33700 2.25800   1.000 21.36207  ? 119 PRO H HB2  1 
ATOM   1808 H HB3  . PRO A 1 123 ? 54.42500 -15.73300 2.87500   1.000 21.36207  ? 119 PRO H HB3  1 
ATOM   1809 H HG2  . PRO A 1 123 ? 56.90900 -16.92300 3.39300   1.000 22.89881  ? 119 PRO H HG2  1 
ATOM   1810 H HG3  . PRO A 1 123 ? 55.77000 -16.57900 4.44600   1.000 22.89881  ? 119 PRO H HG3  1 
ATOM   1811 H HD2  . PRO A 1 123 ? 56.08900 -18.99200 3.47900   1.000 21.31380  ? 119 PRO H HD2  1 
ATOM   1812 H HD3  . PRO A 1 123 ? 54.69800 -18.49500 4.06600   1.000 21.31380  ? 119 PRO H HD3  1 
ATOM   1813 N N    . SER A 1 124 ? 56.16400 -16.11700 -0.52400  1.000 17.59791  ? 120 SER H N    1 
ATOM   1814 C CA   . SER A 1 124 ? 57.32100 -15.70400 -1.30200  1.000 19.59934  ? 120 SER H CA   1 
ATOM   1815 C C    . SER A 1 124 ? 57.84500 -14.40800 -0.69800  1.000 17.81833  ? 120 SER H C    1 
ATOM   1816 O O    . SER A 1 124 ? 57.06200 -13.53000 -0.32700  1.000 19.73972  ? 120 SER H O    1 
ATOM   1817 C CB   . SER A 1 124 ? 56.95100 -15.50500 -2.76900  1.000 18.61689  ? 120 SER H CB   1 
ATOM   1818 O OG   . SER A 1 124 ? 56.48200 -16.71800 -3.33300  1.000 23.95041  ? 120 SER H OG   1 
ATOM   1819 H H    . SER A 1 124 ? 55.44100 -15.70800 -0.74600  1.000 21.12106  ? 120 SER H H    1 
ATOM   1820 H HA   . SER A 1 124 ? 58.01800 -16.37700 -1.27800  1.000 23.52278  ? 120 SER H HA   1 
ATOM   1821 H HB2  . SER A 1 124 ? 56.25300 -14.83400 -2.83200  1.000 22.34384  ? 120 SER H HB2  1 
ATOM   1822 H HB3  . SER A 1 124 ? 57.73700 -15.21200 -3.25700  1.000 22.34384  ? 120 SER H HB3  1 
ATOM   1823 H HG   . SER A 1 124 ? 55.76600 -16.95000 -2.95900  1.000 28.74407  ? 120 SER H HG   1 
ATOM   1824 N N    . VAL A 1 125 ? 59.16400 -14.30400 -0.56400  1.000 17.32782  ? 121 VAL H N    1 
ATOM   1825 C CA   . VAL A 1 125 ? 59.80100 -13.15100 0.06400   1.000 13.92531  ? 121 VAL H CA   1 
ATOM   1826 C C    . VAL A 1 125 ? 60.68400 -12.47600 -0.97300  1.000 17.66862  ? 121 VAL H C    1 
ATOM   1827 O O    . VAL A 1 125 ? 61.61600 -13.09500 -1.50200  1.000 19.63865  ? 121 VAL H O    1 
ATOM   1828 C CB   . VAL A 1 125 ? 60.61500 -13.54700 1.30400   1.000 16.71714  ? 121 VAL H CB   1 
ATOM   1829 C CG1  . VAL A 1 125 ? 61.24100 -12.31400 1.93100   1.000 17.48851  ? 121 VAL H CG1  1 
ATOM   1830 C CG2  . VAL A 1 125 ? 59.72700 -14.26900 2.30800   1.000 15.19643  ? 121 VAL H CG2  1 
ATOM   1831 H H    . VAL A 1 125 ? 59.72200 -14.90100 -0.83400  1.000 20.79696  ? 121 VAL H H    1 
ATOM   1832 H HA   . VAL A 1 125 ? 59.11600 -12.52100 0.33700   1.000 16.71394  ? 121 VAL H HA   1 
ATOM   1833 H HB   . VAL A 1 125 ? 61.32800 -14.15100 1.04300   1.000 20.06414  ? 121 VAL H HB   1 
ATOM   1834 H HG11 . VAL A 1 125 ? 61.65900 -12.56300 2.77000   1.000 20.98979  ? 121 VAL H HG11 1 
ATOM   1835 H HG12 . VAL A 1 125 ? 61.90600 -11.95400 1.32400   1.000 20.98979  ? 121 VAL H HG12 1 
ATOM   1836 H HG13 . VAL A 1 125 ? 60.54700 -11.65400 2.09100   1.000 20.98979  ? 121 VAL H HG13 1 
ATOM   1837 H HG21 . VAL A 1 125 ? 60.23700 -14.43900 3.11600   1.000 18.23929  ? 121 VAL H HG21 1 
ATOM   1838 H HG22 . VAL A 1 125 ? 58.96100 -13.71100 2.51100   1.000 18.23929  ? 121 VAL H HG22 1 
ATOM   1839 H HG23 . VAL A 1 125 ? 59.43200 -15.10900 1.92100   1.000 18.23929  ? 121 VAL H HG23 1 
ATOM   1840 N N    . PHE A 1 126 ? 60.39300 -11.21400 -1.26400  1.000 15.00660  ? 122 PHE H N    1 
ATOM   1841 C CA   . PHE A 1 126 ? 61.14700 -10.46700 -2.25100  1.000 16.99793  ? 122 PHE H CA   1 
ATOM   1842 C C    . PHE A 1 126 ? 61.79500 -9.26100  -1.59100  1.000 16.11511  ? 122 PHE H C    1 
ATOM   1843 O O    . PHE A 1 126 ? 61.23000 -8.68900  -0.65500  1.000 14.05620  ? 122 PHE H O    1 
ATOM   1844 C CB   . PHE A 1 126 ? 60.24700 -9.99600  -3.39800  1.000 16.97760  ? 122 PHE H CB   1 
ATOM   1845 C CG   . PHE A 1 126 ? 59.53300 -11.11500 -4.10100  1.000 19.20928  ? 122 PHE H CG   1 
ATOM   1846 C CD1  . PHE A 1 126 ? 60.24600 -12.06100 -4.81400  1.000 19.59771  ? 122 PHE H CD1  1 
ATOM   1847 C CD2  . PHE A 1 126 ? 58.15200 -11.22100 -4.05200  1.000 19.06910  ? 122 PHE H CD2  1 
ATOM   1848 C CE1  . PHE A 1 126 ? 59.59900 -13.09400 -5.46300  1.000 20.95797  ? 122 PHE H CE1  1 
ATOM   1849 C CE2  . PHE A 1 126 ? 57.49900 -12.25800 -4.70400  1.000 19.74905  ? 122 PHE H CE2  1 
ATOM   1850 C CZ   . PHE A 1 126 ? 58.22600 -13.19200 -5.40900  1.000 20.03803  ? 122 PHE H CZ   1 
ATOM   1851 H H    . PHE A 1 126 ? 59.75600 -10.76800 -0.89700  1.000 18.01149  ? 122 PHE H H    1 
ATOM   1852 H HA   . PHE A 1 126 ? 61.84100 -11.02800 -2.63100  1.000 20.40109  ? 122 PHE H HA   1 
ATOM   1853 H HB2  . PHE A 1 126 ? 59.57500 -9.39400  -3.04200  1.000 20.37670  ? 122 PHE H HB2  1 
ATOM   1854 H HB3  . PHE A 1 126 ? 60.79200 -9.53400  -4.05400  1.000 20.37670  ? 122 PHE H HB3  1 
ATOM   1855 H HD1  . PHE A 1 126 ? 61.17300 -12.00100 -4.85700  1.000 23.52082  ? 122 PHE H HD1  1 
ATOM   1856 H HD2  . PHE A 1 126 ? 57.65900 -10.59200 -3.57800  1.000 22.88649  ? 122 PHE H HD2  1 
ATOM   1857 H HE1  . PHE A 1 126 ? 60.09100 -13.72500 -5.93700  1.000 25.15313  ? 122 PHE H HE1  1 
ATOM   1858 H HE2  . PHE A 1 126 ? 56.57200 -12.32200 -4.66600  1.000 23.70243  ? 122 PHE H HE2  1 
ATOM   1859 H HZ   . PHE A 1 126 ? 57.79100 -13.88800 -5.84700  1.000 24.04921  ? 122 PHE H HZ   1 
ATOM   1860 N N    . PRO A 1 127 ? 62.97400 -8.85100  -2.04500  1.000 16.93633  ? 123 PRO H N    1 
ATOM   1861 C CA   . PRO A 1 127 ? 63.63600 -7.70500  -1.41500  1.000 17.38770  ? 123 PRO H CA   1 
ATOM   1862 C C    . PRO A 1 127 ? 63.02500 -6.38500  -1.85700  1.000 18.31769  ? 123 PRO H C    1 
ATOM   1863 O O    . PRO A 1 127 ? 62.59000 -6.22600  -3.00000  1.000 16.68602  ? 123 PRO H O    1 
ATOM   1864 C CB   . PRO A 1 127 ? 65.08800 -7.83700  -1.89000  1.000 18.03771  ? 123 PRO H CB   1 
ATOM   1865 C CG   . PRO A 1 127 ? 64.96900 -8.49300  -3.23000  1.000 20.63845  ? 123 PRO H CG   1 
ATOM   1866 C CD   . PRO A 1 127 ? 63.77900 -9.41900  -3.14500  1.000 19.32827  ? 123 PRO H CD   1 
ATOM   1867 H HA   . PRO A 1 127 ? 63.59700 -7.77100  -0.44800  1.000 20.86881  ? 123 PRO H HA   1 
ATOM   1868 H HB2  . PRO A 1 127 ? 65.49700 -6.96000  -1.96300  1.000 21.64883  ? 123 PRO H HB2  1 
ATOM   1869 H HB3  . PRO A 1 127 ? 65.59300 -8.38800  -1.27300  1.000 21.64883  ? 123 PRO H HB3  1 
ATOM   1870 H HG2  . PRO A 1 127 ? 64.82900 -7.81700  -3.91100  1.000 24.76971  ? 123 PRO H HG2  1 
ATOM   1871 H HG3  . PRO A 1 127 ? 65.77900 -8.99200  -3.42000  1.000 24.76971  ? 123 PRO H HG3  1 
ATOM   1872 H HD2  . PRO A 1 127 ? 63.27800 -9.41400  -3.97600  1.000 23.19749  ? 123 PRO H HD2  1 
ATOM   1873 H HD3  . PRO A 1 127 ? 64.06100 -10.32300 -2.93400  1.000 23.19749  ? 123 PRO H HD3  1 
ATOM   1874 N N    . LEU A 1 128 ? 62.97200 -5.44300  -0.92200  1.000 18.74955  ? 124 LEU H N    1 
ATOM   1875 C CA   . LEU A 1 128 ? 62.72400 -4.03100  -1.21400  1.000 20.03879  ? 124 LEU H CA   1 
ATOM   1876 C C    . LEU A 1 128 ? 64.08200 -3.35000  -1.05600  1.000 21.99893  ? 124 LEU H C    1 
ATOM   1877 O O    . LEU A 1 128 ? 64.47800 -2.96200  0.04500   1.000 23.01855  ? 124 LEU H O    1 
ATOM   1878 C CB   . LEU A 1 128 ? 61.67000 -3.44400  -0.29600  1.000 17.61714  ? 124 LEU H CB   1 
ATOM   1879 C CG   . LEU A 1 128 ? 60.28300 -4.06100  -0.49400  1.000 16.81819  ? 124 LEU H CG   1 
ATOM   1880 C CD1  . LEU A 1 128 ? 59.34900 -3.66400  0.64400   1.000 19.61943  ? 124 LEU H CD1  1 
ATOM   1881 C CD2  . LEU A 1 128 ? 59.70400 -3.65500  -1.84900  1.000 19.56920  ? 124 LEU H CD2  1 
ATOM   1882 H H    . LEU A 1 128 ? 63.07900 -5.60100  -0.08300  1.000 22.50303  ? 124 LEU H H    1 
ATOM   1883 H HA   . LEU A 1 128 ? 62.39700 -3.91600  -2.12000  1.000 24.05012  ? 124 LEU H HA   1 
ATOM   1884 H HB2  . LEU A 1 128 ? 61.93600 -3.59600  0.62400   1.000 21.14414  ? 124 LEU H HB2  1 
ATOM   1885 H HB3  . LEU A 1 128 ? 61.60000 -2.49200  -0.46900  1.000 21.14414  ? 124 LEU H HB3  1 
ATOM   1886 H HG   . LEU A 1 128 ? 60.36200 -5.02800  -0.48400  1.000 20.18540  ? 124 LEU H HG   1 
ATOM   1887 H HD11 . LEU A 1 128 ? 58.47900 -4.06500  0.49200   1.000 23.54688  ? 124 LEU H HD11 1 
ATOM   1888 H HD12 . LEU A 1 128 ? 59.71900 -3.98400  1.48200   1.000 23.54688  ? 124 LEU H HD12 1 
ATOM   1889 H HD13 . LEU A 1 128 ? 59.27000 -2.69800  0.66500   1.000 23.54688  ? 124 LEU H HD13 1 
ATOM   1890 H HD21 . LEU A 1 128 ? 58.80600 -4.01300  -1.92900  1.000 23.48661  ? 124 LEU H HD21 1 
ATOM   1891 H HD22 . LEU A 1 128 ? 59.68100 -2.68700  -1.90600  1.000 23.48661  ? 124 LEU H HD22 1 
ATOM   1892 H HD23 . LEU A 1 128 ? 60.26700 -4.01400  -2.55300  1.000 23.48661  ? 124 LEU H HD23 1 
ATOM   1893 N N    . ALA A 1 129 ? 64.79800 -3.21900  -2.16500  1.000 23.51866  ? 125 ALA H N    1 
ATOM   1894 C CA   . ALA A 1 129 ? 66.22300 -2.93100  -2.08100  1.000 28.44884  ? 125 ALA H CA   1 
ATOM   1895 C C    . ALA A 1 129 ? 66.47700 -1.43000  -2.01900  1.000 27.42599  ? 125 ALA H C    1 
ATOM   1896 O O    . ALA A 1 129 ? 65.78900 -0.65600  -2.68800  1.000 28.51769  ? 125 ALA H O    1 
ATOM   1897 C CB   . ALA A 1 129 ? 66.95800 -3.51700  -3.28500  1.000 30.06719  ? 125 ALA H CB   1 
ATOM   1898 H H    . ALA A 1 129 ? 64.48900 -3.29100  -2.96400  1.000 28.22596  ? 125 ALA H H    1 
ATOM   1899 H HA   . ALA A 1 129 ? 66.58300 -3.32800  -1.27200  1.000 34.14218  ? 125 ALA H HA   1 
ATOM   1900 H HB1  . ALA A 1 129 ? 67.90400 -3.32100  -3.20400  1.000 36.08420  ? 125 ALA H HB1  1 
ATOM   1901 H HB2  . ALA A 1 129 ? 66.81900 -4.47700  -3.30300  1.000 36.08420  ? 125 ALA H HB2  1 
ATOM   1902 H HB3  . ALA A 1 129 ? 66.60500 -3.11800  -4.09600  1.000 36.08420  ? 125 ALA H HB3  1 
ATOM   1903 N N    . PRO A 1 130 ? 67.45400 -0.99800  -1.22600  1.000 34.55829  ? 126 PRO H N    1 
ATOM   1904 C CA   . PRO A 1 130 ? 67.90100 0.39600   -1.30700  1.000 37.09782  ? 126 PRO H CA   1 
ATOM   1905 C C    . PRO A 1 130 ? 68.82900 0.57600   -2.49600  1.000 48.31809  ? 126 PRO H C    1 
ATOM   1906 O O    . PRO A 1 130 ? 69.62400 -0.30700  -2.82500  1.000 49.41864  ? 126 PRO H O    1 
ATOM   1907 C CB   . PRO A 1 130 ? 68.63800 0.60200   0.02000   1.000 40.75834  ? 126 PRO H CB   1 
ATOM   1908 C CG   . PRO A 1 130 ? 69.22200 -0.74700  0.30800   1.000 40.53890  ? 126 PRO H CG   1 
ATOM   1909 C CD   . PRO A 1 130 ? 68.24300 -1.76800  -0.24400  1.000 35.42848  ? 126 PRO H CD   1 
ATOM   1910 H HA   . PRO A 1 130 ? 67.15800 1.01800   -1.35900  1.000 44.52095  ? 126 PRO H HA   1 
ATOM   1911 H HB2  . PRO A 1 130 ? 69.33200 1.27200   -0.08100  1.000 48.91358  ? 126 PRO H HB2  1 
ATOM   1912 H HB3  . PRO A 1 130 ? 68.01500 0.87200   0.71300   1.000 48.91358  ? 126 PRO H HB3  1 
ATOM   1913 H HG2  . PRO A 1 130 ? 70.08300 -0.82800  -0.13100  1.000 48.65025  ? 126 PRO H HG2  1 
ATOM   1914 H HG3  . PRO A 1 130 ? 69.32600 -0.85800  1.26600   1.000 48.65025  ? 126 PRO H HG3  1 
ATOM   1915 H HD2  . PRO A 1 130 ? 68.71400 -2.49700  -0.67700  1.000 42.51774  ? 126 PRO H HD2  1 
ATOM   1916 H HD3  . PRO A 1 130 ? 67.67300 -2.11400  0.46100   1.000 42.51774  ? 126 PRO H HD3  1 
ATOM   1917 N N    . SER A 1 131 ? 68.71500 1.72400   -3.15700  1.000 61.99812  ? 127 SER H N    1 
ATOM   1918 C CA   . SER A 1 131 ? 69.57900 2.00100   -4.29600  1.000 71.20762  ? 127 SER H CA   1 
ATOM   1919 C C    . SER A 1 131 ? 71.01900 2.18000   -3.82500  1.000 76.79759  ? 127 SER H C    1 
ATOM   1920 O O    . SER A 1 131 ? 71.28400 2.84900   -2.82200  1.000 71.98817  ? 127 SER H O    1 
ATOM   1921 C CB   . SER A 1 131 ? 69.10300 3.24600   -5.04500  1.000 73.24823  ? 127 SER H CB   1 
ATOM   1922 O OG   . SER A 1 131 ? 69.22500 4.40900   -4.24800  1.000 77.31748  ? 127 SER H OG   1 
ATOM   1923 H H    . SER A 1 131 ? 68.15400 2.34800   -2.96800  1.000 74.40132  ? 127 SER H H    1 
ATOM   1924 H HA   . SER A 1 131 ? 69.54800 1.25800   -4.91800  1.000 85.45272  ? 127 SER H HA   1 
ATOM   1925 H HB2  . SER A 1 131 ? 69.64200 3.35500   -5.84400  1.000 87.90144  ? 127 SER H HB2  1 
ATOM   1926 H HB3  . SER A 1 131 ? 68.17100 3.12800   -5.28600  1.000 87.90144  ? 127 SER H HB3  1 
ATOM   1927 H HG   . SER A 1 131 ? 69.99000 4.74500   -4.34500  1.000 92.78455  ? 127 SER H HG   1 
ATOM   1928 N N    . SER A 1 132 ? 71.95200 1.56100   -4.55400  1.000 76.44770  ? 128 SER H N    1 
ATOM   1929 C CA   . SER A 1 132 ? 73.35900 1.62600   -4.16900  1.000 76.51793  ? 128 SER H CA   1 
ATOM   1930 C C    . SER A 1 132 ? 73.83800 3.06500   -4.03300  1.000 84.72789  ? 128 SER H C    1 
ATOM   1931 O O    . SER A 1 132 ? 74.71000 3.35300   -3.20300  1.000 78.24849  ? 128 SER H O    1 
ATOM   1932 C CB   . SER A 1 132 ? 74.21300 0.87000   -5.18800  1.000 73.99852  ? 128 SER H CB   1 
ATOM   1933 O OG   . SER A 1 132 ? 73.89300 1.26000   -6.51400  1.000 76.44845  ? 128 SER H OG   1 
ATOM   1934 H H    . SER A 1 132 ? 71.79800 1.10300   -5.26600  1.000 91.74081  ? 128 SER H H    1 
ATOM   1935 H HA   . SER A 1 132 ? 73.46900 1.19500   -3.30700  1.000 91.82509  ? 128 SER H HA   1 
ATOM   1936 H HB2  . SER A 1 132 ? 75.14900 1.06500   -5.02100  1.000 88.80180  ? 128 SER H HB2  1 
ATOM   1937 H HB3  . SER A 1 132 ? 74.05000 -0.08100  -5.09200  1.000 88.80180  ? 128 SER H HB3  1 
ATOM   1938 H HG   . SER A 1 132 ? 74.38300 0.85200   -7.06000  1.000 91.74172  ? 128 SER H HG   1 
ATOM   1939 N N    . LYS A 1 133 ? 73.28300 3.97800   -4.82500  1.000 84.35749  ? 129 LYS H N    1 
ATOM   1940 C CA   . LYS A 1 133 ? 73.59900 5.39900   -4.75300  1.000 77.02803  ? 129 LYS H CA   1 
ATOM   1941 C C    . LYS A 1 133 ? 72.39500 6.12900   -4.17100  1.000 71.61805  ? 129 LYS H C    1 
ATOM   1942 O O    . LYS A 1 133 ? 71.31700 6.14000   -4.77600  1.000 67.48861  ? 129 LYS H O    1 
ATOM   1943 C CB   . LYS A 1 133 ? 73.97000 5.94200   -6.13200  1.000 68.65884  ? 129 LYS H CB   1 
ATOM   1944 C CG   . LYS A 1 133 ? 75.01900 5.09000   -6.83000  1.000 74.14850  ? 129 LYS H CG   1 
ATOM   1945 C CD   . LYS A 1 133 ? 75.76800 5.85200   -7.91000  1.000 81.39801  ? 129 LYS H CD   1 
ATOM   1946 C CE   . LYS A 1 133 ? 76.84700 4.97600   -8.53500  1.000 77.88835  ? 129 LYS H CE   1 
ATOM   1947 N NZ   . LYS A 1 133 ? 77.65900 5.70300   -9.54700  1.000 76.40885  ? 129 LYS H NZ   1 
ATOM   1948 H H    . LYS A 1 133 ? 72.70200 3.79000   -5.43100  1.000 101.23255 ? 129 LYS H H    1 
ATOM   1949 H HA   . LYS A 1 133 ? 74.35500 5.54600   -4.16300  1.000 92.43721  ? 129 LYS H HA   1 
ATOM   1950 H HB2  . LYS A 1 133 ? 73.17700 5.96000   -6.68900  1.000 82.39418  ? 129 LYS H HB2  1 
ATOM   1951 H HB3  . LYS A 1 133 ? 74.32700 6.83900   -6.03300  1.000 82.39418  ? 129 LYS H HB3  1 
ATOM   1952 H HG2  . LYS A 1 133 ? 75.66700 4.78400   -6.17500  1.000 88.98177  ? 129 LYS H HG2  1 
ATOM   1953 H HG3  . LYS A 1 133 ? 74.58400 4.32900   -7.24600  1.000 88.98177  ? 129 LYS H HG3  1 
ATOM   1954 H HD2  . LYS A 1 133 ? 75.14800 6.12100   -8.60600  1.000 97.68118  ? 129 LYS H HD2  1 
ATOM   1955 H HD3  . LYS A 1 133 ? 76.19100 6.63300   -7.52200  1.000 97.68118  ? 129 LYS H HD3  1 
ATOM   1956 H HE2  . LYS A 1 133 ? 77.44500 4.66400   -7.83800  1.000 93.46959  ? 129 LYS H HE2  1 
ATOM   1957 H HE3  . LYS A 1 133 ? 76.42600 4.22000   -8.97400  1.000 93.46959  ? 129 LYS H HE3  1 
ATOM   1958 H HZ1  . LYS A 1 133 ? 78.27100 5.15900   -9.89500  1.000 91.69419  ? 129 LYS H HZ1  1 
ATOM   1959 H HZ2  . LYS A 1 133 ? 77.13500 6.00300   -10.20100 1.000 91.69419  ? 129 LYS H HZ2  1 
ATOM   1960 H HZ3  . LYS A 1 133 ? 78.07100 6.39500   -9.16700  1.000 91.69419  ? 129 LYS H HZ3  1 
ATOM   1961 N N    . SER A 1 134 ? 72.58800 6.73200   -2.99900  1.000 69.10789  ? 130 SER H N    1 
ATOM   1962 C CA   . SER A 1 134 ? 71.48300 7.29500   -2.23500  1.000 64.78797  ? 130 SER H CA   1 
ATOM   1963 C C    . SER A 1 134 ? 70.64300 8.24900   -3.07400  1.000 62.72783  ? 130 SER H C    1 
ATOM   1964 O O    . SER A 1 134 ? 71.16700 9.03200   -3.86900  1.000 60.20802  ? 130 SER H O    1 
ATOM   1965 C CB   . SER A 1 134 ? 72.02400 8.03300   -1.00700  1.000 53.99840  ? 130 SER H CB   1 
ATOM   1966 O OG   . SER A 1 134 ? 71.14200 9.06900   -0.60800  1.000 51.24897  ? 130 SER H OG   1 
ATOM   1967 H H    . SER A 1 134 ? 73.35500 6.82900   -2.62300  1.000 82.93303  ? 130 SER H H    1 
ATOM   1968 H HA   . SER A 1 134 ? 70.90700 6.57000   -1.94600  1.000 77.74913  ? 130 SER H HA   1 
ATOM   1969 H HB2  . SER A 1 134 ? 72.11900 7.40200   -0.27700  1.000 64.80165  ? 130 SER H HB2  1 
ATOM   1970 H HB3  . SER A 1 134 ? 72.88600 8.42000   -1.22600  1.000 64.80165  ? 130 SER H HB3  1 
ATOM   1971 H HG   . SER A 1 134 ? 71.32600 9.31800   0.17300   1.000 61.50234  ? 130 SER H HG   1 
ATOM   1972 N N    . THR A 1 135 ? 69.32400 8.17000   -2.88400  1.000 63.47772  ? 131 THR H N    1 
ATOM   1973 C CA   . THR A 1 135 ? 68.39200 9.15800   -3.40900  1.000 58.20803  ? 131 THR H CA   1 
ATOM   1974 C C    . THR A 1 135 ? 67.90600 10.12700  -2.33800  1.000 51.80856  ? 131 THR H C    1 
ATOM   1975 O O    . THR A 1 135 ? 67.36900 11.18800  -2.67700  1.000 42.11825  ? 131 THR H O    1 
ATOM   1976 C CB   . THR A 1 135 ? 67.17200 8.46800   -4.03700  1.000 62.78775  ? 131 THR H CB   1 
ATOM   1977 O OG1  . THR A 1 135 ? 66.29700 7.99700   -3.00300  1.000 59.24849  ? 131 THR H OG1  1 
ATOM   1978 C CG2  . THR A 1 135 ? 67.60300 7.29200   -4.90800  1.000 66.10857  ? 131 THR H CG2  1 
ATOM   1979 H H    . THR A 1 135 ? 68.94000 7.53800   -2.44400  1.000 76.17684  ? 131 THR H H    1 
ATOM   1980 H HA   . THR A 1 135 ? 68.83500 9.66400   -4.10700  1.000 69.85321  ? 131 THR H HA   1 
ATOM   1981 H HB   . THR A 1 135 ? 66.70000 9.10400   -4.59600  1.000 75.34887  ? 131 THR H HB   1 
ATOM   1982 H HG1  . THR A 1 135 ? 65.85000 8.63600   -2.69100  1.000 71.10175  ? 131 THR H HG1  1 
ATOM   1983 H HG21 . THR A 1 135 ? 66.83900 6.93900   -5.39000  1.000 79.33385  ? 131 THR H HG21 1 
ATOM   1984 H HG22 . THR A 1 135 ? 68.27300 7.58000   -5.54700  1.000 79.33385  ? 131 THR H HG22 1 
ATOM   1985 H HG23 . THR A 1 135 ? 67.97800 6.58900   -4.35400  1.000 79.33385  ? 131 THR H HG23 1 
ATOM   1986 N N    . SER A 1 136 ? 68.08200 9.78600   -1.06600  1.000 53.03809  ? 132 SER H N    1 
ATOM   1987 C CA   . SER A 1 136 ? 67.60500 10.56600  0.06200   1.000 50.51795  ? 132 SER H CA   1 
ATOM   1988 C C    . SER A 1 136 ? 68.78800 11.17100  0.81600   1.000 47.01729  ? 132 SER H C    1 
ATOM   1989 O O    . SER A 1 136 ? 69.94100 11.09200  0.37800   1.000 49.57779  ? 132 SER H O    1 
ATOM   1990 C CB   . SER A 1 136 ? 66.75200 9.67700   0.96600   1.000 52.17815  ? 132 SER H CB   1 
ATOM   1991 O OG   . SER A 1 136 ? 67.44000 8.46900   1.24900   1.000 51.38859  ? 132 SER H OG   1 
ATOM   1992 H H    . SER A 1 136 ? 68.49600 9.07300   -0.82300  1.000 63.64928  ? 132 SER H H    1 
ATOM   1993 H HA   . SER A 1 136 ? 67.05600 11.29500  -0.26800  1.000 60.62511  ? 132 SER H HA   1 
ATOM   1994 H HB2  . SER A 1 136 ? 66.57400 10.14500  1.79700   1.000 62.61735  ? 132 SER H HB2  1 
ATOM   1995 H HB3  . SER A 1 136 ? 65.91800 9.47100   0.51600   1.000 62.61735  ? 132 SER H HB3  1 
ATOM   1996 H HG   . SER A 1 136 ? 67.10800 8.10200   1.92800   1.000 61.66988  ? 132 SER H HG   1 
ATOM   1997 N N    . GLY A 1 137 ? 68.49900 11.77400  1.96700   1.000 52.13876  ? 133 GLY H N    1 
ATOM   1998 C CA   . GLY A 1 137 ? 69.52000 12.44500  2.74500   1.000 46.09773  ? 133 GLY H CA   1 
ATOM   1999 C C    . GLY A 1 137 ? 69.91000 11.69700  4.00000   1.000 48.21844  ? 133 GLY H C    1 
ATOM   2000 O O    . GLY A 1 137 ? 69.31500 11.89200  5.06400   1.000 46.17918  ? 133 GLY H O    1 
ATOM   2001 H H    . GLY A 1 137 ? 67.71300 11.80600  2.31600   1.000 62.57009  ? 133 GLY H H    1 
ATOM   2002 H HA2  . GLY A 1 137 ? 70.31400 12.55300  2.19900   1.000 55.32084  ? 133 GLY H HA2  1 
ATOM   2003 H HA3  . GLY A 1 137 ? 69.19400 13.32100  3.00500   1.000 55.32084  ? 133 GLY H HA3  1 
ATOM   2004 N N    . GLY A 1 138 ? 70.90400 10.83800  3.88900   1.000 44.16834  ? 134 GLY H N    1 
ATOM   2005 C CA   . GLY A 1 138 ? 71.42700 10.13000  5.04800   1.000 39.49872  ? 134 GLY H CA   1 
ATOM   2006 C C    . GLY A 1 138 ? 70.69300 8.86500   5.42200   1.000 39.39811  ? 134 GLY H C    1 
ATOM   2007 O O    . GLY A 1 138 ? 71.32000 7.83800   5.67700   1.000 42.26011  ? 134 GLY H O    1 
ATOM   2008 H H    . GLY A 1 138 ? 71.29700 10.64400  3.15000   1.000 53.00557  ? 134 GLY H H    1 
ATOM   2009 H HA2  . GLY A 1 138 ? 72.35100 9.89200   4.87200   1.000 47.40204  ? 134 GLY H HA2  1 
ATOM   2010 H HA3  . GLY A 1 138 ? 71.39500 10.72500  5.81300   1.000 47.40204  ? 134 GLY H HA3  1 
ATOM   2011 N N    . THR A 1 139 ? 69.36400 8.92100   5.45700   1.000 38.23790  ? 135 THR H N    1 
ATOM   2012 C CA   . THR A 1 139 ? 68.54000 7.79300   5.87000   1.000 35.94776  ? 135 THR H CA   1 
ATOM   2013 C C    . THR A 1 139 ? 68.04200 7.05100   4.63400   1.000 35.02932  ? 135 THR H C    1 
ATOM   2014 O O    . THR A 1 139 ? 67.39000 7.64600   3.76900   1.000 34.02758  ? 135 THR H O    1 
ATOM   2015 C CB   . THR A 1 139 ? 67.36000 8.26500   6.72100   1.000 40.01896  ? 135 THR H CB   1 
ATOM   2016 O OG1  . THR A 1 139 ? 67.84400 8.93000   7.89600   1.000 39.21832  ? 135 THR H OG1  1 
ATOM   2017 C CG2  . THR A 1 139 ? 66.49300 7.08800   7.13100   1.000 36.27918  ? 135 THR H CG2  1 
ATOM   2018 H H    . THR A 1 139 ? 68.90900 9.61800   5.24200   1.000 45.88906  ? 135 THR H H    1 
ATOM   2019 H HA   . THR A 1 139 ? 69.07600 7.18100   6.39800   1.000 43.14088  ? 135 THR H HA   1 
ATOM   2020 H HB   . THR A 1 139 ? 66.81800 8.88100   6.20400   1.000 48.02632  ? 135 THR H HB   1 
ATOM   2021 H HG1  . THR A 1 139 ? 68.28900 9.60900   7.67900   1.000 47.06555  ? 135 THR H HG1  1 
ATOM   2022 H HG21 . THR A 1 139 ? 65.83400 7.37300   7.78400   1.000 43.53858  ? 135 THR H HG21 1 
ATOM   2023 H HG22 . THR A 1 139 ? 66.03300 6.72900   6.35600   1.000 43.53858  ? 135 THR H HG22 1 
ATOM   2024 H HG23 . THR A 1 139 ? 67.04300 6.39100   7.52200   1.000 43.53858  ? 135 THR H HG23 1 
ATOM   2025 N N    . ALA A 1 140 ? 68.35500 5.76000   4.55500   1.000 29.30674  ? 136 ALA H N    1 
ATOM   2026 C CA   . ALA A 1 140 ? 67.90300 4.89400   3.47700   1.000 26.21713  ? 136 ALA H CA   1 
ATOM   2027 C C    . ALA A 1 140 ? 66.82900 3.95200   3.99800   1.000 27.66045  ? 136 ALA H C    1 
ATOM   2028 O O    . ALA A 1 140 ? 66.77000 3.64100   5.18900   1.000 26.45882  ? 136 ALA H O    1 
ATOM   2029 C CB   . ALA A 1 140 ? 69.06000 4.07700   2.89400   1.000 28.89870  ? 136 ALA H CB   1 
ATOM   2030 H H    . ALA A 1 140 ? 68.84300 5.35300   5.13300   1.000 35.17166  ? 136 ALA H H    1 
ATOM   2031 H HA   . ALA A 1 140 ? 67.53100 5.43700   2.76400   1.000 31.46413  ? 136 ALA H HA   1 
ATOM   2032 H HB1  . ALA A 1 140 ? 68.71900 3.50800   2.18600   1.000 34.68201  ? 136 ALA H HB1  1 
ATOM   2033 H HB2  . ALA A 1 140 ? 69.72700 4.68500   2.53800   1.000 34.68201  ? 136 ALA H HB2  1 
ATOM   2034 H HB3  . ALA A 1 140 ? 69.44900 3.53400   3.59700   1.000 34.68201  ? 136 ALA H HB3  1 
ATOM   2035 N N    . ALA A 1 141 ? 65.98100 3.48700   3.08800   1.000 22.05699  ? 137 ALA H N    1 
ATOM   2036 C CA   . ALA A 1 141 ? 64.91200 2.56300   3.43100   1.000 22.02870  ? 137 ALA H CA   1 
ATOM   2037 C C    . ALA A 1 141 ? 65.09900 1.27200   2.65100   1.000 20.89789  ? 137 ALA H C    1 
ATOM   2038 O O    . ALA A 1 141 ? 65.50600 1.28600   1.48400   1.000 19.45551  ? 137 ALA H O    1 
ATOM   2039 C CB   . ALA A 1 141 ? 63.53400 3.16400   3.14500   1.000 23.16018  ? 137 ALA H CB   1 
ATOM   2040 H H    . ALA A 1 141 ? 66.00700 3.69600   2.25500   1.000 26.47195  ? 137 ALA H H    1 
ATOM   2041 H HA   . ALA A 1 141 ? 64.94800 2.35800   4.37800   1.000 26.43800  ? 137 ALA H HA   1 
ATOM   2042 H HB1  . ALA A 1 141 ? 62.85200 2.51500   3.37500   1.000 27.79578  ? 137 ALA H HB1  1 
ATOM   2043 H HB2  . ALA A 1 141 ? 63.42200 3.96600   3.68000   1.000 27.79578  ? 137 ALA H HB2  1 
ATOM   2044 H HB3  . ALA A 1 141 ? 63.47500 3.38500   2.20200   1.000 27.79578  ? 137 ALA H HB3  1 
ATOM   2045 N N    . LEU A 1 142 ? 64.83100 0.15900   3.32000   1.000 19.93742  ? 138 LEU H N    1 
ATOM   2046 C CA   . LEU A 1 142 ? 64.88600 -1.15300  2.69900   1.000 20.83790  ? 138 LEU H CA   1 
ATOM   2047 C C    . LEU A 1 142 ? 63.88100 -2.03400  3.42100   1.000 20.51880  ? 138 LEU H C    1 
ATOM   2048 O O    . LEU A 1 142 ? 63.38800 -1.69000  4.49800   1.000 16.79623  ? 138 LEU H O    1 
ATOM   2049 C CB   . LEU A 1 142 ? 66.29600 -1.73600  2.75700   1.000 22.24650  ? 138 LEU H CB   1 
ATOM   2050 C CG   . LEU A 1 142 ? 66.85600 -1.96200  4.15800   1.000 25.20831  ? 138 LEU H CG   1 
ATOM   2051 C CD1  . LEU A 1 142 ? 66.75700 -3.43400  4.53800   1.000 27.60861  ? 138 LEU H CD1  1 
ATOM   2052 C CD2  . LEU A 1 142 ? 68.28900 -1.48100  4.23800   1.000 29.01910  ? 138 LEU H CD2  1 
ATOM   2053 H H    . LEU A 1 142 ? 64.60900 0.13900   4.15100   1.000 23.92848  ? 138 LEU H H    1 
ATOM   2054 H HA   . LEU A 1 142 ? 64.63600 -1.09800  1.76400   1.000 25.00905  ? 138 LEU H HA   1 
ATOM   2055 H HB2  . LEU A 1 142 ? 66.28800 -2.59500  2.30700   1.000 26.69937  ? 138 LEU H HB2  1 
ATOM   2056 H HB3  . LEU A 1 142 ? 66.89600 -1.12700  2.30000   1.000 26.69937  ? 138 LEU H HB3  1 
ATOM   2057 H HG   . LEU A 1 142 ? 66.33500 -1.45200  4.79800   1.000 30.25354  ? 138 LEU H HG   1 
ATOM   2058 H HD11 . LEU A 1 142 ? 67.07800 -3.54800  5.44700   1.000 33.13390  ? 138 LEU H HD11 1 
ATOM   2059 H HD12 . LEU A 1 142 ? 65.83000 -3.71300  4.47800   1.000 33.13390  ? 138 LEU H HD12 1 
ATOM   2060 H HD13 . LEU A 1 142 ? 67.30000 -3.95500  3.92700   1.000 33.13390  ? 138 LEU H HD13 1 
ATOM   2061 H HD21 . LEU A 1 142 ? 68.62500 -1.63700  5.13500   1.000 34.82649  ? 138 LEU H HD21 1 
ATOM   2062 H HD22 . LEU A 1 142 ? 68.82300 -1.97300  3.59500   1.000 34.82649  ? 138 LEU H HD22 1 
ATOM   2063 H HD23 . LEU A 1 142 ? 68.31600 -0.53300  4.03500   1.000 34.82649  ? 138 LEU H HD23 1 
ATOM   2064 N N    . GLY A 1 143 ? 63.56700 -3.17200  2.81900   1.000 18.02775  ? 139 GLY H N    1 
ATOM   2065 C CA   . GLY A 1 143 ? 62.62000 -4.07100  3.44700   1.000 15.51561  ? 139 GLY H CA   1 
ATOM   2066 C C    . GLY A 1 143 ? 62.46500 -5.34400  2.65000   1.000 17.88826  ? 139 GLY H C    1 
ATOM   2067 O O    . GLY A 1 143 ? 63.24000 -5.62700  1.73400   1.000 15.17558  ? 139 GLY H O    1 
ATOM   2068 H H    . GLY A 1 143 ? 63.88100 -3.43900  2.06400   1.000 21.63687  ? 139 GLY H H    1 
ATOM   2069 H HA2  . GLY A 1 143 ? 62.92700 -4.29800  4.33800   1.000 18.62230  ? 139 GLY H HA2  1 
ATOM   2070 H HA3  . GLY A 1 143 ? 61.75400 -3.63900  3.51200   1.000 18.62230  ? 139 GLY H HA3  1 
ATOM   2071 N N    . CYS A 1 144 ? 61.45700 -6.12200  3.02800   1.000 18.10939  ? 140 CYS H N    1 
ATOM   2072 C CA   A CYS A 1 144 ? 61.08700 -7.36400  2.36200   0.760 17.89861  ? 140 CYS H CA   1 
ATOM   2073 C CA   B CYS A 1 144 ? 61.10300 -7.27400  2.21900   0.240 17.74900  ? 140 CYS H CA   1 
ATOM   2074 C C    . CYS A 1 144 ? 59.58800 -7.36300  2.10800   1.000 17.47832  ? 140 CYS H C    1 
ATOM   2075 O O    . CYS A 1 144 ? 58.82500 -6.96100  2.99100   1.000 17.08782  ? 140 CYS H O    1 
ATOM   2076 C CB   A CYS A 1 144 ? 61.41400 -8.57500  3.22000   0.760 16.60640  ? 140 CYS H CB   1 
ATOM   2077 C CB   B CYS A 1 144 ? 61.76300 -8.58000  2.73500   0.240 17.65833  ? 140 CYS H CB   1 
ATOM   2078 S SG   A CYS A 1 144 ? 63.13400 -8.97500  3.38500   0.760 20.16954  ? 140 CYS H SG   1 
ATOM   2079 S SG   B CYS A 1 144 ? 61.44800 -9.19500  4.40500   0.240 19.85911  ? 140 CYS H SG   1 
ATOM   2080 H H    A CYS A 1 144 ? 60.95000 -5.94300  3.69900   0.760 21.73484  ? 140 CYS H H    1 
ATOM   2081 H H    B CYS A 1 144 ? 60.97800 -6.00300  3.73200   0.240 21.73484  ? 140 CYS H H    1 
ATOM   2082 H HA   A CYS A 1 144 ? 61.56600 -7.42700  1.52200   0.760 21.48190  ? 140 CYS H HA   1 
ATOM   2083 H HA   B CYS A 1 144 ? 61.43000 -7.16500  1.31200   0.240 21.30237  ? 140 CYS H HA   1 
ATOM   2084 H HB2  A CYS A 1 144 ? 61.07100 -8.41500  4.11300   0.760 19.93125  ? 140 CYS H HB2  1 
ATOM   2085 H HB2  B CYS A 1 144 ? 61.48700 -9.29100  2.13600   0.240 21.19357  ? 140 CYS H HB2  1 
ATOM   2086 H HB3  A CYS A 1 144 ? 60.97700 -9.34800  2.83000   0.760 19.93125  ? 140 CYS H HB3  1 
ATOM   2087 H HB3  B CYS A 1 144 ? 62.72300 -8.45300  2.67800   0.240 21.19357  ? 140 CYS H HB3  1 
ATOM   2088 N N    . LEU A 1 145 ? 59.17900 -7.82200  0.93300   1.000 14.94683  ? 141 LEU H N    1 
ATOM   2089 C CA   . LEU A 1 145 ? 57.78100 -7.97800  0.56300   1.000 15.35756  ? 141 LEU H CA   1 
ATOM   2090 C C    . LEU A 1 145 ? 57.44600 -9.45200  0.73000   1.000 16.33721  ? 141 LEU H C    1 
ATOM   2091 O O    . LEU A 1 145 ? 58.09900 -10.30800 0.12600   1.000 17.31862  ? 141 LEU H O    1 
ATOM   2092 C CB   . LEU A 1 145 ? 57.55200 -7.51100  -0.87200  1.000 14.04635  ? 141 LEU H CB   1 
ATOM   2093 C CG   . LEU A 1 145 ? 56.21500 -7.81800  -1.54400  1.000 15.15694  ? 141 LEU H CG   1 
ATOM   2094 C CD1  . LEU A 1 145 ? 55.06000 -7.17700  -0.80500  1.000 15.54710  ? 141 LEU H CD1  1 
ATOM   2095 C CD2  . LEU A 1 145 ? 56.24600 -7.34100  -2.98800  1.000 16.25781  ? 141 LEU H CD2  1 
ATOM   2096 H H    . LEU A 1 145 ? 59.71700 -8.06000  0.30500   1.000 17.93977  ? 141 LEU H H    1 
ATOM   2097 H HA   . LEU A 1 145 ? 57.20100 -7.45100  1.13400   1.000 18.43265  ? 141 LEU H HA   1 
ATOM   2098 H HB2  . LEU A 1 145 ? 57.65000 -6.54600  -0.88300  1.000 16.85919  ? 141 LEU H HB2  1 
ATOM   2099 H HB3  . LEU A 1 145 ? 58.23700 -7.91900  -1.42400  1.000 16.85919  ? 141 LEU H HB3  1 
ATOM   2100 H HG   . LEU A 1 145 ? 56.07000 -8.77700  -1.52600  1.000 18.19189  ? 141 LEU H HG   1 
ATOM   2101 H HD11 . LEU A 1 145 ? 54.23200 -7.40000  -1.25800  1.000 18.66009  ? 141 LEU H HD11 1 
ATOM   2102 H HD12 . LEU A 1 145 ? 55.04100 -7.51500  0.10400   1.000 18.66009  ? 141 LEU H HD12 1 
ATOM   2103 H HD13 . LEU A 1 145 ? 55.18500 -6.21500  -0.79700  1.000 18.66009  ? 141 LEU H HD13 1 
ATOM   2104 H HD21 . LEU A 1 145 ? 55.40100 -7.56200  -3.41100  1.000 19.51295  ? 141 LEU H HD21 1 
ATOM   2105 H HD22 . LEU A 1 145 ? 56.38100 -6.38100  -3.00100  1.000 19.51295  ? 141 LEU H HD22 1 
ATOM   2106 H HD23 . LEU A 1 145 ? 56.97400 -7.78400  -3.45100  1.000 19.51295  ? 141 LEU H HD23 1 
ATOM   2107 N N    . VAL A 1 146 ? 56.47200 -9.74300  1.58500   1.000 16.46874  ? 142 VAL H N    1 
ATOM   2108 C CA   . VAL A 1 146 ? 56.05900 -11.10400 1.90500   1.000 15.42696  ? 142 VAL H CA   1 
ATOM   2109 C C    . VAL A 1 146 ? 54.70600 -11.30700 1.24400   1.000 15.59713  ? 142 VAL H C    1 
ATOM   2110 O O    . VAL A 1 146 ? 53.70900 -10.70900 1.66600   1.000 14.13665  ? 142 VAL H O    1 
ATOM   2111 C CB   . VAL A 1 146 ? 55.97800 -11.34000 3.41700   1.000 15.76793  ? 142 VAL H CB   1 
ATOM   2112 C CG1  . VAL A 1 146 ? 55.77000 -12.81900 3.71100   1.000 17.80909  ? 142 VAL H CG1  1 
ATOM   2113 C CG2  . VAL A 1 146 ? 57.23100 -10.82900 4.11300   1.000 16.40799  ? 142 VAL H CG2  1 
ATOM   2114 H H    . VAL A 1 146 ? 56.02000 -9.14700  2.00800   1.000 19.76605  ? 142 VAL H H    1 
ATOM   2115 H HA   . VAL A 1 146 ? 56.69500 -11.73800 1.53700   1.000 18.51592  ? 142 VAL H HA   1 
ATOM   2116 H HB   . VAL A 1 146 ? 55.22000 -10.84800 3.76900   1.000 18.92508  ? 142 VAL H HB   1 
ATOM   2117 H HG11 . VAL A 1 146 ? 55.68800 -12.94100 4.67000   1.000 21.37447  ? 142 VAL H HG11 1 
ATOM   2118 H HG12 . VAL A 1 146 ? 54.96100 -13.11800 3.26900   1.000 21.37447  ? 142 VAL H HG12 1 
ATOM   2119 H HG13 . VAL A 1 146 ? 56.53300 -13.31700 3.37800   1.000 21.37447  ? 142 VAL H HG13 1 
ATOM   2120 H HG21 . VAL A 1 146 ? 57.17200 -11.03300 5.05900   1.000 19.69315  ? 142 VAL H HG21 1 
ATOM   2121 H HG22 . VAL A 1 146 ? 58.00600 -11.26600 3.72700   1.000 19.69315  ? 142 VAL H HG22 1 
ATOM   2122 H HG23 . VAL A 1 146 ? 57.29400 -9.87000  3.98400   1.000 19.69315  ? 142 VAL H HG23 1 
ATOM   2123 N N    . LYS A 1 147 ? 54.66000 -12.14300 0.21500   1.000 18.26877  ? 143 LYS H N    1 
ATOM   2124 C CA   . LYS A 1 147 ? 53.54400 -12.13700 -0.71700  1.000 18.44916  ? 143 LYS H CA   1 
ATOM   2125 C C    . LYS A 1 147 ? 52.96100 -13.53100 -0.88000  1.000 16.41663  ? 143 LYS H C    1 
ATOM   2126 O O    . LYS A 1 147 ? 53.69200 -14.52400 -0.88500  1.000 16.88621  ? 143 LYS H O    1 
ATOM   2127 C CB   . LYS A 1 147 ? 54.00900 -11.58900 -2.08000  1.000 20.31831  ? 143 LYS H CB   1 
ATOM   2128 C CG   . LYS A 1 147 ? 52.90100 -11.03100 -2.93900  1.000 21.63970  ? 143 LYS H CG   1 
ATOM   2129 C CD   . LYS A 1 147 ? 53.45400 -10.45700 -4.22900  1.000 23.89023  ? 143 LYS H CD   1 
ATOM   2130 C CE   . LYS A 1 147 ? 52.54000 -10.75000 -5.39300  1.000 24.64003  ? 143 LYS H CE   1 
ATOM   2131 N NZ   . LYS A 1 147 ? 51.20300 -10.13800 -5.21000  1.000 23.94973  ? 143 LYS H NZ   1 
ATOM   2132 H H    . LYS A 1 147 ? 55.26700 -12.72500 0.03600   1.000 21.92610  ? 143 LYS H H    1 
ATOM   2133 H HA   . LYS A 1 147 ? 52.83000 -11.58100 -0.37000  1.000 22.14256  ? 143 LYS H HA   1 
ATOM   2134 H HB2  . LYS A 1 147 ? 54.64700 -10.87500 -1.92500  1.000 24.38555  ? 143 LYS H HB2  1 
ATOM   2135 H HB3  . LYS A 1 147 ? 54.43000 -12.30900 -2.57500  1.000 24.38555  ? 143 LYS H HB3  1 
ATOM   2136 H HG2  . LYS A 1 147 ? 52.27600 -11.73900 -3.16100  1.000 25.97121  ? 143 LYS H HG2  1 
ATOM   2137 H HG3  . LYS A 1 147 ? 52.44400 -10.32400 -2.45900  1.000 25.97121  ? 143 LYS H HG3  1 
ATOM   2138 H HD2  . LYS A 1 147 ? 53.54100 -9.49500  -4.14200  1.000 28.67184  ? 143 LYS H HD2  1 
ATOM   2139 H HD3  . LYS A 1 147 ? 54.32000 -10.85300 -4.41300  1.000 28.67184  ? 143 LYS H HD3  1 
ATOM   2140 H HE2  . LYS A 1 147 ? 52.93000 -10.39000 -6.20500  1.000 29.57160  ? 143 LYS H HE2  1 
ATOM   2141 H HE3  . LYS A 1 147 ? 52.42500 -11.70900 -5.47700  1.000 29.57160  ? 143 LYS H HE3  1 
ATOM   2142 H HZ1  . LYS A 1 147 ? 50.66100 -10.38600 -5.87100  1.000 28.74325  ? 143 LYS H HZ1  1 
ATOM   2143 H HZ2  . LYS A 1 147 ? 50.85200 -10.40000 -4.43500  1.000 28.74325  ? 143 LYS H HZ2  1 
ATOM   2144 H HZ3  . LYS A 1 147 ? 51.27200 -9.25000  -5.21100  1.000 28.74325  ? 143 LYS H HZ3  1 
ATOM   2145 N N    . ASP A 1 148 ? 51.63100 -13.59100 -1.00100  1.000 15.77773  ? 144 ASP H N    1 
ATOM   2146 C CA   . ASP A 1 148 ? 50.92100 -14.78500 -1.45200  1.000 17.45713  ? 144 ASP H CA   1 
ATOM   2147 C C    . ASP A 1 148 ? 51.03000 -15.92400 -0.45400  1.000 17.98937  ? 144 ASP H C    1 
ATOM   2148 O O    . ASP A 1 148 ? 51.48900 -17.02800 -0.79000  1.000 19.79928  ? 144 ASP H O    1 
ATOM   2149 C CB   . ASP A 1 148 ? 51.43400 -15.20500 -2.83100  1.000 18.68756  ? 144 ASP H CB   1 
ATOM   2150 C CG   . ASP A 1 148 ? 51.15000 -14.16500 -3.89300  1.000 20.43844  ? 144 ASP H CG   1 
ATOM   2151 O OD1  . ASP A 1 148 ? 50.33600 -13.25800 -3.62500  1.000 19.89858  ? 144 ASP H OD1  1 
ATOM   2152 O OD2  . ASP A 1 148 ? 51.74000 -14.25100 -4.99000  1.000 23.85044  ? 144 ASP H OD2  1 
ATOM   2153 H H    . ASP A 1 148 ? 51.10600 -12.93500 -0.82100  1.000 18.93685  ? 144 ASP H H    1 
ATOM   2154 H HA   . ASP A 1 148 ? 49.97600 -14.57800 -1.52900  1.000 20.95213  ? 144 ASP H HA   1 
ATOM   2155 H HB2  . ASP A 1 148 ? 52.39500 -15.33500 -2.78600  1.000 22.42865  ? 144 ASP H HB2  1 
ATOM   2156 H HB3  . ASP A 1 148 ? 50.99900 -16.03100 -3.09400  1.000 22.42865  ? 144 ASP H HB3  1 
ATOM   2157 N N    . TYR A 1 149 ? 50.59100 -15.68000 0.77400   1.000 15.33801  ? 145 TYR H N    1 
ATOM   2158 C CA   . TYR A 1 149 ? 50.56000 -16.70600 1.79900   1.000 13.55594  ? 145 TYR H CA   1 
ATOM   2159 C C    . TYR A 1 149 ? 49.16700 -16.79900 2.40300   1.000 12.67605  ? 145 TYR H C    1 
ATOM   2160 O O    . TYR A 1 149 ? 48.33800 -15.89700 2.26300   1.000 12.16649  ? 145 TYR H O    1 
ATOM   2161 C CB   . TYR A 1 149 ? 51.59200 -16.44300 2.90100   1.000 15.99829  ? 145 TYR H CB   1 
ATOM   2162 C CG   . TYR A 1 149 ? 51.35600 -15.18900 3.71500   1.000 14.35788  ? 145 TYR H CG   1 
ATOM   2163 C CD1  . TYR A 1 149 ? 51.87700 -13.96700 3.30900   1.000 14.67692  ? 145 TYR H CD1  1 
ATOM   2164 C CD2  . TYR A 1 149 ? 50.63200 -15.23100 4.89900   1.000 12.77582  ? 145 TYR H CD2  1 
ATOM   2165 C CE1  . TYR A 1 149 ? 51.67800 -12.82200 4.05200   1.000 13.59702  ? 145 TYR H CE1  1 
ATOM   2166 C CE2  . TYR A 1 149 ? 50.42200 -14.08500 5.64900   1.000 15.58732  ? 145 TYR H CE2  1 
ATOM   2167 C CZ   . TYR A 1 149 ? 50.95200 -12.88600 5.22200   1.000 14.97745  ? 145 TYR H CZ   1 
ATOM   2168 O OH   . TYR A 1 149 ? 50.75200 -11.74000 5.96100   1.000 14.54753  ? 145 TYR H OH   1 
ATOM   2169 H H    . TYR A 1 149 ? 50.30200 -14.91500 1.04000   1.000 18.40918  ? 145 TYR H H    1 
ATOM   2170 H HA   . TYR A 1 149 ? 50.76600 -17.56100 1.39100   1.000 16.27070  ? 145 TYR H HA   1 
ATOM   2171 H HB2  . TYR A 1 149 ? 51.58300 -17.19300 3.51600   1.000 19.20152  ? 145 TYR H HB2  1 
ATOM   2172 H HB3  . TYR A 1 149 ? 52.46700 -16.36100 2.49000   1.000 19.20152  ? 145 TYR H HB3  1 
ATOM   2173 H HD1  . TYR A 1 149 ? 52.36900 -13.92100 2.52100   1.000 17.61588  ? 145 TYR H HD1  1 
ATOM   2174 H HD2  . TYR A 1 149 ? 50.28300 -16.04100 5.19400   1.000 15.33456  ? 145 TYR H HD2  1 
ATOM   2175 H HE1  . TYR A 1 149 ? 52.03100 -12.01100 3.76400   1.000 16.31999  ? 145 TYR H HE1  1 
ATOM   2176 H HE2  . TYR A 1 149 ? 49.92700 -14.12500 6.43500   1.000 18.70835  ? 145 TYR H HE2  1 
ATOM   2177 H HH   . TYR A 1 149 ? 50.28900 -11.91400 6.64000   1.000 17.46061  ? 145 TYR H HH   1 
ATOM   2178 N N    . PHE A 1 150 ? 48.91400 -17.92100 3.05900   1.000 13.67770  ? 146 PHE H N    1 
ATOM   2179 C CA   . PHE A 1 150 ? 47.63300 -18.15800 3.70300   1.000 12.86641  ? 146 PHE H CA   1 
ATOM   2180 C C    . PHE A 1 150 ? 47.76500 -19.33400 4.65800   1.000 12.42372  ? 146 PHE H C    1 
ATOM   2181 O O    . PHE A 1 150 ? 48.45400 -20.31000 4.34000   1.000 12.07597  ? 146 PHE H O    1 
ATOM   2182 C CB   . PHE A 1 150 ? 46.54100 -18.44500 2.67400   1.000 14.29704  ? 146 PHE H CB   1 
ATOM   2183 C CG   . PHE A 1 150 ? 45.17400 -18.52700 3.27500   1.000 13.65615  ? 146 PHE H CG   1 
ATOM   2184 C CD1  . PHE A 1 150 ? 44.68800 -19.72700 3.77000   1.000 15.59768  ? 146 PHE H CD1  1 
ATOM   2185 C CD2  . PHE A 1 150 ? 44.38500 -17.39500 3.37600   1.000 16.80912  ? 146 PHE H CD2  1 
ATOM   2186 C CE1  . PHE A 1 150 ? 43.43600 -19.79500 4.34400   1.000 17.46831  ? 146 PHE H CE1  1 
ATOM   2187 C CE2  . PHE A 1 150 ? 43.13100 -17.45600 3.94600   1.000 17.02840  ? 146 PHE H CE2  1 
ATOM   2188 C CZ   . PHE A 1 150 ? 42.65500 -18.65500 4.43500   1.000 17.97859  ? 146 PHE H CZ   1 
ATOM   2189 H H    . PHE A 1 150 ? 49.47400 -18.56800 3.14600   1.000 16.41681  ? 146 PHE H H    1 
ATOM   2190 H HA   . PHE A 1 150 ? 47.37400 -17.36600 4.20000   1.000 15.44326  ? 146 PHE H HA   1 
ATOM   2191 H HB2  . PHE A 1 150 ? 46.53500 -17.73300 2.01500   1.000 17.16002  ? 146 PHE H HB2  1 
ATOM   2192 H HB3  . PHE A 1 150 ? 46.73000 -19.29300 2.24400   1.000 17.16002  ? 146 PHE H HB3  1 
ATOM   2193 H HD1  . PHE A 1 150 ? 45.21100 -20.49400 3.71500   1.000 18.72078  ? 146 PHE H HD1  1 
ATOM   2194 H HD2  . PHE A 1 150 ? 44.70400 -16.58300 3.05600   1.000 20.17452  ? 146 PHE H HD2  1 
ATOM   2195 H HE1  . PHE A 1 150 ? 43.11600 -20.60600 4.67000   1.000 20.96554  ? 146 PHE H HE1  1 
ATOM   2196 H HE2  . PHE A 1 150 ? 42.60600 -16.69000 4.00100   1.000 20.43765  ? 146 PHE H HE2  1 
ATOM   2197 H HZ   . PHE A 1 150 ? 41.81200 -18.69800 4.82400   1.000 21.57788  ? 146 PHE H HZ   1 
ATOM   2198 N N    . PRO A 1 151 ? 47.14700 -19.28100 5.84500   1.000 13.17492  ? 147 PRO H N    1 
ATOM   2199 C CA   . PRO A 1 151 ? 46.43000 -18.14900 6.43800   1.000 14.95761  ? 147 PRO H CA   1 
ATOM   2200 C C    . PRO A 1 151 ? 47.40600 -17.20600 7.11300   1.000 13.90721  ? 147 PRO H C    1 
ATOM   2201 O O    . PRO A 1 151 ? 48.61500 -17.41900 7.02500   1.000 13.25692  ? 147 PRO H O    1 
ATOM   2202 C CB   . PRO A 1 151 ? 45.52600 -18.81900 7.46600   1.000 13.52664  ? 147 PRO H CB   1 
ATOM   2203 C CG   . PRO A 1 151 ? 46.36000 -19.96000 7.95200   1.000 17.70859  ? 147 PRO H CG   1 
ATOM   2204 C CD   . PRO A 1 151 ? 47.16600 -20.43800 6.75900   1.000 14.58734  ? 147 PRO H CD   1 
ATOM   2205 H HA   . PRO A 1 151 ? 45.88200 -17.67500 5.79400   1.000 17.95270  ? 147 PRO H HA   1 
ATOM   2206 H HB2  . PRO A 1 151 ? 45.31500 -18.20200 8.18500   1.000 16.23554  ? 147 PRO H HB2  1 
ATOM   2207 H HB3  . PRO A 1 151 ? 44.70900 -19.13000 7.04600   1.000 16.23554  ? 147 PRO H HB3  1 
ATOM   2208 H HG2  . PRO A 1 151 ? 46.94700 -19.65500 8.66100   1.000 21.25387  ? 147 PRO H HG2  1 
ATOM   2209 H HG3  . PRO A 1 151 ? 45.78300 -20.66800 8.28000   1.000 21.25387  ? 147 PRO H HG3  1 
ATOM   2210 H HD2  . PRO A 1 151 ? 48.07400 -20.65500 7.02100   1.000 17.50838  ? 147 PRO H HD2  1 
ATOM   2211 H HD3  . PRO A 1 151 ? 46.74700 -21.21000 6.34700   1.000 17.50838  ? 147 PRO H HD3  1 
ATOM   2212 N N    . GLU A 1 152 ? 46.89600 -16.18500 7.79000   1.000 14.50735  ? 148 GLU H N    1 
ATOM   2213 C CA   . GLU A 1 152 ? 47.72800 -15.43900 8.70900   1.000 14.91634  ? 148 GLU H CA   1 
ATOM   2214 C C    . GLU A 1 152 ? 48.09400 -16.33400 9.89100   1.000 18.73915  ? 148 GLU H C    1 
ATOM   2215 O O    . GLU A 1 152 ? 47.45400 -17.36200 10.12300  1.000 15.05661  ? 148 GLU H O    1 
ATOM   2216 C CB   . GLU A 1 152 ? 47.00600 -14.19000 9.19700   1.000 18.53796  ? 148 GLU H CB   1 
ATOM   2217 C CG   . GLU A 1 152 ? 46.71700 -13.17900 8.11300   1.000 18.89769  ? 148 GLU H CG   1 
ATOM   2218 C CD   . GLU A 1 152 ? 46.51400 -11.78700 8.66700   1.000 25.63975  ? 148 GLU H CD   1 
ATOM   2219 O OE1  . GLU A 1 152 ? 47.48400 -11.21900 9.21600   1.000 32.13055  ? 148 GLU H OE1  1 
ATOM   2220 O OE2  . GLU A 1 152 ? 45.38400 -11.26700 8.56300   1.000 26.14005  ? 148 GLU H OE2  1 
ATOM   2221 H H    . GLU A 1 152 ? 46.08300 -15.91300 7.73300   1.000 17.41240  ? 148 GLU H H    1 
ATOM   2222 H HA   . GLU A 1 152 ? 48.54100 -15.14800 8.26500   1.000 17.90318  ? 148 GLU H HA   1 
ATOM   2223 H HB2  . GLU A 1 152 ? 46.15800 -14.45500 9.58600   1.000 22.24912  ? 148 GLU H HB2  1 
ATOM   2224 H HB3  . GLU A 1 152 ? 47.55700 -13.75500 9.86600   1.000 22.24912  ? 148 GLU H HB3  1 
ATOM   2225 H HG2  . GLU A 1 152 ? 47.46400 -13.15200 7.49600   1.000 22.68080  ? 148 GLU H HG2  1 
ATOM   2226 H HG3  . GLU A 1 152 ? 45.90800 -13.43800 7.64400   1.000 22.68080  ? 148 GLU H HG3  1 
ATOM   2227 N N    . PRO A 1 153 ? 49.11800 -15.96100 10.66900  1.000 18.46828  ? 149 PRO H N    1 
ATOM   2228 C CA   . PRO A 1 153 ? 50.00200 -14.81000 10.49900  1.000 17.97817  ? 149 PRO H CA   1 
ATOM   2229 C C    . PRO A 1 153 ? 51.39200 -15.18600 10.02200  1.000 17.46754  ? 149 PRO H C    1 
ATOM   2230 O O    . PRO A 1 153 ? 51.78400 -16.34300 10.15600  1.000 16.02655  ? 149 PRO H O    1 
ATOM   2231 C CB   . PRO A 1 153 ? 50.08300 -14.24800 11.91500  1.000 18.40727  ? 149 PRO H CB   1 
ATOM   2232 C CG   . PRO A 1 153 ? 50.09400 -15.50900 12.76600  1.000 19.67848  ? 149 PRO H CG   1 
ATOM   2233 C CD   . PRO A 1 153 ? 49.24600 -16.53400 12.02400  1.000 17.85747  ? 149 PRO H CD   1 
ATOM   2234 H HA   . PRO A 1 153 ? 49.61200 -14.16700 9.88600   1.000 21.57738  ? 149 PRO H HA   1 
ATOM   2235 H HB2  . PRO A 1 153 ? 50.89600 -13.73300 12.03100  1.000 22.09229  ? 149 PRO H HB2  1 
ATOM   2236 H HB3  . PRO A 1 153 ? 49.31000 -13.69500 12.10700  1.000 22.09229  ? 149 PRO H HB3  1 
ATOM   2237 H HG2  . PRO A 1 153 ? 51.00500 -15.82600 12.86600  1.000 23.61774  ? 149 PRO H HG2  1 
ATOM   2238 H HG3  . PRO A 1 153 ? 49.71300 -15.31600 13.63700  1.000 23.61774  ? 149 PRO H HG3  1 
ATOM   2239 H HD2  . PRO A 1 153 ? 49.69400 -17.39400 11.99300  1.000 21.43254  ? 149 PRO H HD2  1 
ATOM   2240 H HD3  . PRO A 1 153 ? 48.37500 -16.62800 12.44100  1.000 21.43254  ? 149 PRO H HD3  1 
ATOM   2241 N N    . VAL A 1 154 ? 52.12600 -14.21900 9.48200   1.000 17.86881  ? 150 VAL H N    1 
ATOM   2242 C CA   . VAL A 1 154 ? 53.57600 -14.30700 9.41100   1.000 16.84648  ? 150 VAL H CA   1 
ATOM   2243 C C    . VAL A 1 154 ? 54.12900 -13.34400 10.45200  1.000 20.77925  ? 150 VAL H C    1 
ATOM   2244 O O    . VAL A 1 154 ? 53.46800 -12.37600 10.85000  1.000 21.14876  ? 150 VAL H O    1 
ATOM   2245 C CB   . VAL A 1 154 ? 54.15900 -13.98700 8.02000   1.000 18.34709  ? 150 VAL H CB   1 
ATOM   2246 C CG1  . VAL A 1 154 ? 53.54400 -14.88900 6.96600   1.000 19.79123  ? 150 VAL H CG1  1 
ATOM   2247 C CG2  . VAL A 1 154 ? 53.96300 -12.52400 7.67400   1.000 18.25882  ? 150 VAL H CG2  1 
ATOM   2248 H H    . VAL A 1 154 ? 51.80100 -13.49600 9.14800   1.000 21.44614  ? 150 VAL H H    1 
ATOM   2249 H HA   . VAL A 1 154 ? 53.84100 -15.21800 9.61200   1.000 20.21935  ? 150 VAL H HA   1 
ATOM   2250 H HB   . VAL A 1 154 ? 55.11500 -14.15400 8.03500   1.000 22.02008  ? 150 VAL H HB   1 
ATOM   2251 H HG11 . VAL A 1 154 ? 53.82600 -14.58800 6.08900   1.000 23.75305  ? 150 VAL H HG11 1 
ATOM   2252 H HG12 . VAL A 1 154 ? 53.84500 -15.79900 7.11600   1.000 23.75305  ? 150 VAL H HG12 1 
ATOM   2253 H HG13 . VAL A 1 154 ? 52.57800 -14.84400 7.03700   1.000 23.75305  ? 150 VAL H HG13 1 
ATOM   2254 H HG21 . VAL A 1 154 ? 54.14800 -12.39500 6.73000   1.000 21.91415  ? 150 VAL H HG21 1 
ATOM   2255 H HG22 . VAL A 1 154 ? 53.04700 -12.27400 7.86900   1.000 21.91415  ? 150 VAL H HG22 1 
ATOM   2256 H HG23 . VAL A 1 154 ? 54.57300 -11.98900 8.20600   1.000 21.91415  ? 150 VAL H HG23 1 
ATOM   2257 N N    . THR A 1 155 ? 55.33800 -13.62800 10.91100  1.000 18.34711  ? 151 THR H N    1 
ATOM   2258 C CA   . THR A 1 155 ? 56.09700 -12.70600 11.73700  1.000 22.44912  ? 151 THR H CA   1 
ATOM   2259 C C    . THR A 1 155 ? 57.37000 -12.35000 10.98600  1.000 22.12990  ? 151 THR H C    1 
ATOM   2260 O O    . THR A 1 155 ? 57.89300 -13.15500 10.21000  1.000 18.22844  ? 151 THR H O    1 
ATOM   2261 C CB   . THR A 1 155 ? 56.42600 -13.30900 13.10500  1.000 21.26834  ? 151 THR H CB   1 
ATOM   2262 O OG1  . THR A 1 155 ? 57.31600 -14.41800 12.94700  1.000 25.12048  ? 151 THR H OG1  1 
ATOM   2263 C CG2  . THR A 1 155 ? 55.15400 -13.78600 13.79400  1.000 23.92982  ? 151 THR H CG2  1 
ATOM   2264 H H    . THR A 1 155 ? 55.74900 -14.36700 10.75200  1.000 22.02011  ? 151 THR H H    1 
ATOM   2265 H HA   . THR A 1 155 ? 55.59100 -11.89700 11.90800  1.000 26.94251  ? 151 THR H HA   1 
ATOM   2266 H HB   . THR A 1 155 ? 56.84700 -12.63400 13.66000  1.000 25.52558  ? 151 THR H HB   1 
ATOM   2267 H HG1  . THR A 1 155 ? 58.11200 -14.14900 12.94700  1.000 30.14815  ? 151 THR H HG1  1 
ATOM   2268 H HG21 . THR A 1 155 ? 55.36200 -14.12000 14.68100  1.000 28.71936  ? 151 THR H HG21 1 
ATOM   2269 H HG22 . THR A 1 155 ? 54.52500 -13.05100 13.87500  1.000 28.71936  ? 151 THR H HG22 1 
ATOM   2270 H HG23 . THR A 1 155 ? 54.74300 -14.49700 13.27800  1.000 28.71936  ? 151 THR H HG23 1 
ATOM   2271 N N    . VAL A 1 156 ? 57.84700 -11.12600 11.18700  1.000 18.44611  ? 152 VAL H N    1 
ATOM   2272 C CA   . VAL A 1 156 ? 59.06700 -10.65300 10.55000  1.000 17.71563  ? 152 VAL H CA   1 
ATOM   2273 C C    . VAL A 1 156 ? 59.96300 -10.05900 11.62500  1.000 21.60937  ? 152 VAL H C    1 
ATOM   2274 O O    . VAL A 1 156 ? 59.50200 -9.28200  12.46800  1.000 22.69899  ? 152 VAL H O    1 
ATOM   2275 C CB   . VAL A 1 156 ? 58.78200 -9.61200  9.45000   1.000 19.53810  ? 152 VAL H CB   1 
ATOM   2276 C CG1  . VAL A 1 156 ? 60.05000 -9.30600  8.65100   1.000 19.52866  ? 152 VAL H CG1  1 
ATOM   2277 C CG2  . VAL A 1 156 ? 57.67900 -10.09400 8.53100   1.000 20.70956  ? 152 VAL H CG2  1 
ATOM   2278 H H    . VAL A 1 156 ? 57.47300 -10.54400 11.69800  1.000 22.13891  ? 152 VAL H H    1 
ATOM   2279 H HA   . VAL A 1 156 ? 59.52600 -11.40500 10.14200  1.000 21.26233  ? 152 VAL H HA   1 
ATOM   2280 H HB   . VAL A 1 156 ? 58.48800 -8.78900  9.87200   1.000 23.44929  ? 152 VAL H HB   1 
ATOM   2281 H HG11 . VAL A 1 156 ? 59.83500 -8.67400  7.94800   1.000 23.43797  ? 152 VAL H HG11 1 
ATOM   2282 H HG12 . VAL A 1 156 ? 60.71400 -8.92600  9.24700   1.000 23.43797  ? 152 VAL H HG12 1 
ATOM   2283 H HG13 . VAL A 1 156 ? 60.38500 -10.13000 8.26400   1.000 23.43797  ? 152 VAL H HG13 1 
ATOM   2284 H HG21 . VAL A 1 156 ? 57.55900 -9.45000  7.81500   1.000 24.85504  ? 152 VAL H HG21 1 
ATOM   2285 H HG22 . VAL A 1 156 ? 57.92900 -10.95600 8.16200   1.000 24.85504  ? 152 VAL H HG22 1 
ATOM   2286 H HG23 . VAL A 1 156 ? 56.85800 -10.17900 9.04000   1.000 24.85504  ? 152 VAL H HG23 1 
ATOM   2287 N N    . SER A 1 157 ? 61.23200 -10.44300 11.60600  1.000 17.53595  ? 153 SER H N    1 
ATOM   2288 C CA   . SER A 1 157 ? 62.26200 -9.79100  12.39400  1.000 22.37956  ? 153 SER H CA   1 
ATOM   2289 C C    . SER A 1 157 ? 63.39700 -9.41000  11.45500  1.000 21.30922  ? 153 SER H C    1 
ATOM   2290 O O    . SER A 1 157 ? 63.45700 -9.84900  10.30300  1.000 19.73625  ? 153 SER H O    1 
ATOM   2291 C CB   . SER A 1 157 ? 62.76700 -10.69000 13.52900  1.000 22.80909  ? 153 SER H CB   1 
ATOM   2292 O OG   . SER A 1 157 ? 63.49000 -11.79600 13.02500  1.000 23.55917  ? 153 SER H OG   1 
ATOM   2293 H H    . SER A 1 157 ? 61.52700 -11.09700 11.13100  1.000 21.04671  ? 153 SER H H    1 
ATOM   2294 H HA   . SER A 1 157 ? 61.90900 -8.98700  12.80500  1.000 26.85904  ? 153 SER H HA   1 
ATOM   2295 H HB2  . SER A 1 157 ? 63.34800 -10.17000 14.10500  1.000 27.37448  ? 153 SER H HB2  1 
ATOM   2296 H HB3  . SER A 1 157 ? 62.00500 -11.01600 14.03300  1.000 27.37448  ? 153 SER H HB3  1 
ATOM   2297 H HG   . SER A 1 157 ? 64.21700 -11.53600 12.69200  1.000 28.27458  ? 153 SER H HG   1 
ATOM   2298 N N    . TRP A 1 158 ? 64.29800 -8.57700  11.95800  1.000 19.14665  ? 154 TRP H N    1 
ATOM   2299 C CA   . TRP A 1 158 ? 65.46300 -8.13400  11.20800  1.000 21.71899  ? 154 TRP H CA   1 
ATOM   2300 C C    . TRP A 1 158 ? 66.71800 -8.50500  11.97800  1.000 22.43779  ? 154 TRP H C    1 
ATOM   2301 O O    . TRP A 1 158 ? 66.82400 -8.22200  13.17500  1.000 23.49771  ? 154 TRP H O    1 
ATOM   2302 C CB   . TRP A 1 158 ? 65.38800 -6.62800  10.95000  1.000 20.51837  ? 154 TRP H CB   1 
ATOM   2303 C CG   . TRP A 1 158 ? 64.38400 -6.30600  9.90100   1.000 19.69818  ? 154 TRP H CG   1 
ATOM   2304 C CD1  . TRP A 1 158 ? 63.06000 -6.03200  10.08200  1.000 20.75919  ? 154 TRP H CD1  1 
ATOM   2305 C CD2  . TRP A 1 158 ? 64.61600 -6.25500  8.49400   1.000 18.35756  ? 154 TRP H CD2  1 
ATOM   2306 N NE1  . TRP A 1 158 ? 62.45600 -5.80400  8.87100   1.000 17.13608  ? 154 TRP H NE1  1 
ATOM   2307 C CE2  . TRP A 1 158 ? 63.39200 -5.93400  7.87900   1.000 17.41697  ? 154 TRP H CE2  1 
ATOM   2308 C CE3  . TRP A 1 158 ? 65.74400 -6.44500  7.69200   1.000 20.13895  ? 154 TRP H CE3  1 
ATOM   2309 C CZ2  . TRP A 1 158 ? 63.26400 -5.80100  6.50100   1.000 18.12832  ? 154 TRP H CZ2  1 
ATOM   2310 C CZ3  . TRP A 1 158 ? 65.61500 -6.30300  6.32100   1.000 18.98742  ? 154 TRP H CZ3  1 
ATOM   2311 C CH2  . TRP A 1 158 ? 64.38500 -5.98700  5.74200   1.000 15.90474  ? 154 TRP H CH2  1 
ATOM   2312 H H    . TRP A 1 158 ? 64.25500 -8.24800  12.75100  1.000 22.97955  ? 154 TRP H H    1 
ATOM   2313 H HA   . TRP A 1 158 ? 65.50600 -8.58100  10.34800  1.000 26.06636  ? 154 TRP H HA   1 
ATOM   2314 H HB2  . TRP A 1 158 ? 65.13200 -6.17400  11.76900  1.000 24.62562  ? 154 TRP H HB2  1 
ATOM   2315 H HB3  . TRP A 1 158 ? 66.25500 -6.31000  10.65200  1.000 24.62562  ? 154 TRP H HB3  1 
ATOM   2316 H HD1  . TRP A 1 158 ? 62.63000 -6.00400  10.90600  1.000 24.91459  ? 154 TRP H HD1  1 
ATOM   2317 H HE1  . TRP A 1 158 ? 61.62600 -5.61100  8.75300   1.000 20.56687  ? 154 TRP H HE1  1 
ATOM   2318 H HE3  . TRP A 1 158 ? 66.56500 -6.66200  8.07100   1.000 24.17031  ? 154 TRP H HE3  1 
ATOM   2319 H HZ2  . TRP A 1 158 ? 62.44600 -5.59300  6.11100   1.000 21.75756  ? 154 TRP H HZ2  1 
ATOM   2320 H HZ3  . TRP A 1 158 ? 66.36000 -6.42100  5.77700   1.000 22.78848  ? 154 TRP H HZ3  1 
ATOM   2321 H HH2  . TRP A 1 158 ? 64.32800 -5.90100  4.81700   1.000 19.08925  ? 154 TRP H HH2  1 
ATOM   2322 N N    . ASN A 1 159 ? 67.66100 -9.14200  11.28800  1.000 21.88701  ? 155 ASN H N    1 
ATOM   2323 C CA   . ASN A 1 159 ? 68.91800 -9.56200  11.89700  1.000 25.29930  ? 155 ASN H CA   1 
ATOM   2324 C C    . ASN A 1 159 ? 68.64300 -10.34400 13.17900  1.000 26.82930  ? 155 ASN H C    1 
ATOM   2325 O O    . ASN A 1 159 ? 69.22700 -10.09100 14.23500  1.000 28.78986  ? 155 ASN H O    1 
ATOM   2326 C CB   . ASN A 1 159 ? 69.82900 -8.35900  12.16000  1.000 24.53864  ? 155 ASN H CB   1 
ATOM   2327 C CG   . ASN A 1 159 ? 70.32700 -7.70200  10.87200  1.000 26.05990  ? 155 ASN H CG   1 
ATOM   2328 O OD1  . ASN A 1 159 ? 70.18000 -8.25400  9.78000   1.000 23.62742  ? 155 ASN H OD1  1 
ATOM   2329 N ND2  . ASN A 1 159 ? 70.93100 -6.52400  11.00300  1.000 23.91753  ? 155 ASN H ND2  1 
ATOM   2330 H H    . ASN A 1 159 ? 67.59500 -9.34400  10.45500  1.000 26.26798  ? 155 ASN H H    1 
ATOM   2331 H HA   . ASN A 1 159 ? 69.38500 -10.15000 11.28300  1.000 30.36273  ? 155 ASN H HA   1 
ATOM   2332 H HB2  . ASN A 1 159 ? 69.33600 -7.69400  12.66500  1.000 29.44994  ? 155 ASN H HB2  1 
ATOM   2333 H HB3  . ASN A 1 159 ? 70.60300 -8.65300  12.66500  1.000 29.44994  ? 155 ASN H HB3  1 
ATOM   2334 H HD21 . ASN A 1 159 ? 71.22900 -6.11400  10.30900  1.000 28.70461  ? 155 ASN H HD21 1 
ATOM   2335 H HD22 . ASN A 1 159 ? 71.02400 -6.17300  11.78300  1.000 28.70461  ? 155 ASN H HD22 1 
ATOM   2336 N N    . SER A 1 160 ? 67.70800 -11.29000 13.07900  1.000 27.71053  ? 156 SER H N    1 
ATOM   2337 C CA   . SER A 1 160 ? 67.36700 -12.20500 14.16800  1.000 26.95909  ? 156 SER H CA   1 
ATOM   2338 C C    . SER A 1 160 ? 66.93700 -11.46800 15.43200  1.000 25.49785  ? 156 SER H C    1 
ATOM   2339 O O    . SER A 1 160 ? 67.14100 -11.95800 16.54500  1.000 30.72053  ? 156 SER H O    1 
ATOM   2340 C CB   . SER A 1 160 ? 68.53500 -13.14300 14.48500  1.000 26.94908  ? 156 SER H CB   1 
ATOM   2341 O OG   . SER A 1 160 ? 69.01800 -13.76400 13.30800  1.000 27.35890  ? 156 SER H OG   1 
ATOM   2342 H H    . SER A 1 160 ? 67.24200 -11.42500 12.36800  1.000 33.25621  ? 156 SER H H    1 
ATOM   2343 H HA   . SER A 1 160 ? 66.61200 -12.73900 13.87600  1.000 32.35448  ? 156 SER H HA   1 
ATOM   2344 H HB2  . SER A 1 160 ? 69.25300 -12.62900 14.88700  1.000 32.34246  ? 156 SER H HB2  1 
ATOM   2345 H HB3  . SER A 1 160 ? 68.23200 -13.82800 15.10100  1.000 32.34246  ? 156 SER H HB3  1 
ATOM   2346 H HG   . SER A 1 160 ? 68.37600 -13.95900 12.80200  1.000 32.83425  ? 156 SER H HG   1 
ATOM   2347 N N    . GLY A 1 161 ? 66.32500 -10.29500 15.27300  1.000 26.64969  ? 157 GLY H N    1 
ATOM   2348 C CA   . GLY A 1 161 ? 65.84400 -9.51900  16.39400  1.000 26.80966  ? 157 GLY H CA   1 
ATOM   2349 C C    . GLY A 1 161 ? 66.80100 -8.46400  16.89800  1.000 24.30785  ? 157 GLY H C    1 
ATOM   2350 O O    . GLY A 1 161 ? 66.41600 -7.65300  17.75000  1.000 26.74880  ? 157 GLY H O    1 
ATOM   2351 H H    . GLY A 1 161 ? 66.17800 -9.92800  14.50900  1.000 31.98320  ? 157 GLY H H    1 
ATOM   2352 H HA2  . GLY A 1 161 ? 65.02300 -9.07200  16.13200  1.000 32.17517  ? 157 GLY H HA2  1 
ATOM   2353 H HA3  . GLY A 1 161 ? 65.65400 -10.12200 17.13000  1.000 32.17517  ? 157 GLY H HA3  1 
ATOM   2354 N N    . ALA A 1 162 ? 68.03800 -8.44800  16.40400  1.000 25.80835  ? 158 ALA H N    1 
ATOM   2355 C CA   . ALA A 1 162 ? 68.99000 -7.42800  16.81800  1.000 26.05813  ? 158 ALA H CA   1 
ATOM   2356 C C    . ALA A 1 162 ? 68.63400 -6.04900  16.27600  1.000 28.75924  ? 158 ALA H C    1 
ATOM   2357 O O    . ALA A 1 162 ? 69.03400 -5.04300  16.87200  1.000 30.19902  ? 158 ALA H O    1 
ATOM   2358 C CB   . ALA A 1 162 ? 70.39700 -7.82100  16.36700  1.000 26.76965  ? 158 ALA H CB   1 
ATOM   2359 H H    . ALA A 1 162 ? 68.34600 -9.01300  15.83300  1.000 30.97359  ? 158 ALA H H    1 
ATOM   2360 H HA   . ALA A 1 162 ? 68.98800 -7.37100  17.78600  1.000 31.27333  ? 158 ALA H HA   1 
ATOM   2361 H HB1  . ALA A 1 162 ? 71.02200 -7.13600  16.65100  1.000 32.12715  ? 158 ALA H HB1  1 
ATOM   2362 H HB2  . ALA A 1 162 ? 70.63100 -8.67100  16.77000  1.000 32.12715  ? 158 ALA H HB2  1 
ATOM   2363 H HB3  . ALA A 1 162 ? 70.40800 -7.89900  15.40000  1.000 32.12715  ? 158 ALA H HB3  1 
ATOM   2364 N N    . LEU A 1 163 ? 67.89300 -5.97500  15.17100  1.000 25.08813  ? 159 LEU H N    1 
ATOM   2365 C CA   . LEU A 1 163 ? 67.51700 -4.70800  14.54900  1.000 24.91800  ? 159 LEU H CA   1 
ATOM   2366 C C    . LEU A 1 163 ? 66.02900 -4.48200  14.78300  1.000 25.54827  ? 159 LEU H C    1 
ATOM   2367 O O    . LEU A 1 163 ? 65.18900 -5.20000  14.22900  1.000 27.28987  ? 159 LEU H O    1 
ATOM   2368 C CB   . LEU A 1 163 ? 67.84800 -4.71200  13.05900  1.000 22.78762  ? 159 LEU H CB   1 
ATOM   2369 C CG   . LEU A 1 163 ? 67.48300 -3.44300  12.28700  1.000 25.78928  ? 159 LEU H CG   1 
ATOM   2370 C CD1  . LEU A 1 163 ? 68.13000 -2.21700  12.89600  1.000 27.56813  ? 159 LEU H CD1  1 
ATOM   2371 C CD2  . LEU A 1 163 ? 67.90200 -3.58100  10.84400  1.000 23.75829  ? 159 LEU H CD2  1 
ATOM   2372 H H    . LEU A 1 163 ? 67.58900 -6.66300  14.75500  1.000 30.10932  ? 159 LEU H H    1 
ATOM   2373 H HA   . LEU A 1 163 ? 68.00800 -3.98500  14.96800  1.000 29.90518  ? 159 LEU H HA   1 
ATOM   2374 H HB2  . LEU A 1 163 ? 68.80400 -4.84200  12.96200  1.000 27.34871  ? 159 LEU H HB2  1 
ATOM   2375 H HB3  . LEU A 1 163 ? 67.36900 -5.44700  12.64400  1.000 27.34871  ? 159 LEU H HB3  1 
ATOM   2376 H HG   . LEU A 1 163 ? 66.52200 -3.32000  12.33300  1.000 30.95071  ? 159 LEU H HG   1 
ATOM   2377 H HD11 . LEU A 1 163 ? 67.92100 -1.44500  12.34700  1.000 33.08532  ? 159 LEU H HD11 1 
ATOM   2378 H HD12 . LEU A 1 163 ? 67.78400 -2.08900  13.79200  1.000 33.08532  ? 159 LEU H HD12 1 
ATOM   2379 H HD13 . LEU A 1 163 ? 69.09000 -2.35000  12.92800  1.000 33.08532  ? 159 LEU H HD13 1 
ATOM   2380 H HD21 . LEU A 1 163 ? 67.68600 -2.76100  10.37300  1.000 28.51352  ? 159 LEU H HD21 1 
ATOM   2381 H HD22 . LEU A 1 163 ? 68.85800 -3.74200  10.80600  1.000 28.51352  ? 159 LEU H HD22 1 
ATOM   2382 H HD23 . LEU A 1 163 ? 67.42500 -4.32600  10.44700  1.000 28.51352  ? 159 LEU H HD23 1 
ATOM   2383 N N    . THR A 1 164 ? 65.70700 -3.48500  15.60300  1.000 25.86802  ? 160 THR H N    1 
ATOM   2384 C CA   . THR A 1 164 ? 64.32300 -3.20700  15.96300  1.000 25.70765  ? 160 THR H CA   1 
ATOM   2385 C C    . THR A 1 164 ? 63.99400 -1.73500  15.76400  1.000 26.89812  ? 160 THR H C    1 
ATOM   2386 O O    . THR A 1 164 ? 62.84700 -1.37700  15.47400  1.000 25.18700  ? 160 THR H O    1 
ATOM   2387 C CB   . THR A 1 164 ? 64.07300 -3.59900  17.41800  1.000 27.96868  ? 160 THR H CB   1 
ATOM   2388 O OG1  . THR A 1 164 ? 65.06600 -2.98000  18.24600  1.000 32.45909  ? 160 THR H OG1  1 
ATOM   2389 C CG2  . THR A 1 164 ? 64.13500 -5.10400  17.58300  1.000 25.73856  ? 160 THR H CG2  1 
ATOM   2390 H H    . THR A 1 164 ? 66.27600 -2.95200  15.96500  1.000 31.04520  ? 160 THR H H    1 
ATOM   2391 H HA   . THR A 1 164 ? 63.73900 -3.73000  15.39200  1.000 30.85275  ? 160 THR H HA   1 
ATOM   2392 H HB   . THR A 1 164 ? 63.19000 -3.30500  17.69200  1.000 33.56599  ? 160 THR H HB   1 
ATOM   2393 H HG1  . THR A 1 164 ? 64.95200 -3.20400  19.04700  1.000 38.95448  ? 160 THR H HG1  1 
ATOM   2394 H HG21 . THR A 1 164 ? 63.98900 -5.34200  18.51100  1.000 30.88985  ? 160 THR H HG21 1 
ATOM   2395 H HG22 . THR A 1 164 ? 63.45300 -5.52600  17.03800  1.000 30.88985  ? 160 THR H HG22 1 
ATOM   2396 H HG23 . THR A 1 164 ? 65.00600 -5.43200  17.30700  1.000 30.88985  ? 160 THR H HG23 1 
ATOM   2397 N N    . SER A 1 165 ? 64.99200 -0.87500  15.93100  1.000 29.81900  ? 161 SER H N    1 
ATOM   2398 C CA   . SER A 1 165 ? 64.77400 0.55600   15.78700  1.000 31.92875  ? 161 SER H CA   1 
ATOM   2399 C C    . SER A 1 165 ? 64.49200 0.89500   14.32900  1.000 26.47729  ? 161 SER H C    1 
ATOM   2400 O O    . SER A 1 165 ? 65.24400 0.50500   13.43000  1.000 27.86812  ? 161 SER H O    1 
ATOM   2401 C CB   . SER A 1 165 ? 65.99100 1.32700   16.29300  1.000 32.79836  ? 161 SER H CB   1 
ATOM   2402 O OG   . SER A 1 165 ? 65.70300 2.70800   16.40200  1.000 40.97867  ? 161 SER H OG   1 
ATOM   2403 H H    . SER A 1 165 ? 65.80000 -1.09400  16.12700  1.000 35.78637  ? 161 SER H H    1 
ATOM   2404 H HA   . SER A 1 165 ? 64.00600 0.82500   16.31600  1.000 38.31807  ? 161 SER H HA   1 
ATOM   2405 H HB2  . SER A 1 165 ? 66.23900 0.98600   17.16700  1.000 39.36161  ? 161 SER H HB2  1 
ATOM   2406 H HB3  . SER A 1 165 ? 66.72300 1.20500   15.66900  1.000 39.36161  ? 161 SER H HB3  1 
ATOM   2407 H HG   . SER A 1 165 ? 66.33400 3.10300   16.79100  1.000 49.17797  ? 161 SER H HG   1 
ATOM   2408 N N    . GLY A 1 166 ? 63.39700 1.61500   14.09600  1.000 24.84658  ? 162 GLY H N    1 
ATOM   2409 C CA   . GLY A 1 166 ? 63.04600 2.05400   12.76400  1.000 27.80857  ? 162 GLY H CA   1 
ATOM   2410 C C    . GLY A 1 166 ? 62.34000 1.02500   11.91500  1.000 25.80877  ? 162 GLY H C    1 
ATOM   2411 O O    . GLY A 1 166 ? 62.17500 1.25100   10.71000  1.000 22.31726  ? 162 GLY H O    1 
ATOM   2412 H H    . GLY A 1 166 ? 62.84100 1.86200   14.70400  1.000 29.81947  ? 162 GLY H H    1 
ATOM   2413 H HA2  . GLY A 1 166 ? 62.46300 2.82600   12.83600  1.000 33.37385  ? 162 GLY H HA2  1 
ATOM   2414 H HA3  . GLY A 1 166 ? 63.85700 2.31300   12.30000  1.000 33.37385  ? 162 GLY H HA3  1 
ATOM   2415 N N    . VAL A 1 167 ? 61.91800 -0.09200  12.50100  1.000 21.43643  ? 163 VAL H N    1 
ATOM   2416 C CA   . VAL A 1 167 ? 61.22900 -1.15000  11.77300  1.000 21.75714  ? 163 VAL H CA   1 
ATOM   2417 C C    . VAL A 1 167 ? 59.73700 -0.85400  11.75600  1.000 21.80704  ? 163 VAL H C    1 
ATOM   2418 O O    . VAL A 1 167 ? 59.13800 -0.55000  12.79500  1.000 21.52763  ? 163 VAL H O    1 
ATOM   2419 C CB   . VAL A 1 167 ? 61.49600 -2.52400  12.40900  1.000 21.23766  ? 163 VAL H CB   1 
ATOM   2420 C CG1  . VAL A 1 167 ? 60.57900 -3.57600  11.79900  1.000 23.44945  ? 163 VAL H CG1  1 
ATOM   2421 C CG2  . VAL A 1 167 ? 62.94300 -2.92000  12.24100  1.000 19.96624  ? 163 VAL H CG2  1 
ATOM   2422 H H    . VAL A 1 167 ? 62.02100 -0.26300  13.33800  1.000 25.72729  ? 163 VAL H H    1 
ATOM   2423 H HA   . VAL A 1 167 ? 61.55300 -1.15900  10.85900  1.000 26.11214  ? 163 VAL H HA   1 
ATOM   2424 H HB   . VAL A 1 167 ? 61.31000 -2.47000  13.36000  1.000 25.48876  ? 163 VAL H HB   1 
ATOM   2425 H HG11 . VAL A 1 167 ? 60.88100 -4.45600  12.07400  1.000 28.14291  ? 163 VAL H HG11 1 
ATOM   2426 H HG12 . VAL A 1 167 ? 59.67300 -3.42500  12.11200  1.000 28.14291  ? 163 VAL H HG12 1 
ATOM   2427 H HG13 . VAL A 1 167 ? 60.61200 -3.50200  10.83300  1.000 28.14291  ? 163 VAL H HG13 1 
ATOM   2428 H HG21 . VAL A 1 167 ? 63.07900 -3.79500  12.63600  1.000 23.96306  ? 163 VAL H HG21 1 
ATOM   2429 H HG22 . VAL A 1 167 ? 63.15500 -2.94700  11.29400  1.000 23.96306  ? 163 VAL H HG22 1 
ATOM   2430 H HG23 . VAL A 1 167 ? 63.50400 -2.26500  12.68600  1.000 23.96306  ? 163 VAL H HG23 1 
ATOM   2431 N N    . HIS A 1 168 ? 59.13700 -0.96100  10.57700  1.000 19.12551  ? 164 HIS H N    1 
ATOM   2432 C CA   . HIS A 1 168 ? 57.69300 -0.86900  10.40600  1.000 20.50751  ? 164 HIS H CA   1 
ATOM   2433 C C    . HIS A 1 168 ? 57.25400 -2.09500  9.62300   1.000 20.18843  ? 164 HIS H C    1 
ATOM   2434 O O    . HIS A 1 168 ? 57.57300 -2.22400  8.43700   1.000 18.35758  ? 164 HIS H O    1 
ATOM   2435 C CB   . HIS A 1 168 ? 57.29600 0.41300   9.68000   1.000 22.49815  ? 164 HIS H CB   1 
ATOM   2436 C CG   . HIS A 1 168 ? 57.57900 1.65600   10.46000  1.000 24.15812  ? 164 HIS H CG   1 
ATOM   2437 N ND1  . HIS A 1 168 ? 56.94400 1.94800   11.64800  1.000 26.59897  ? 164 HIS H ND1  1 
ATOM   2438 C CD2  . HIS A 1 168 ? 58.42800 2.68400   10.22400  1.000 26.84957  ? 164 HIS H CD2  1 
ATOM   2439 C CE1  . HIS A 1 168 ? 57.39000 3.10200   12.11000  1.000 27.60901  ? 164 HIS H CE1  1 
ATOM   2440 N NE2  . HIS A 1 168 ? 58.29300 3.56900   11.26600  1.000 24.74752  ? 164 HIS H NE2  1 
ATOM   2441 H H    . HIS A 1 168 ? 59.55900 -1.09200  9.83900   1.000 22.95418  ? 164 HIS H H    1 
ATOM   2442 H HA   . HIS A 1 168 ? 57.25700 -0.86700  11.27200  1.000 24.61258  ? 164 HIS H HA   1 
ATOM   2443 H HB2  . HIS A 1 168 ? 57.79100 0.46700   8.84700   1.000 27.00135  ? 164 HIS H HB2  1 
ATOM   2444 H HB3  . HIS A 1 168 ? 56.34300 0.38700   9.49900   1.000 27.00135  ? 164 HIS H HB3  1 
ATOM   2445 H HD1  . HIS A 1 168 ? 56.35000 1.45600   12.02800  1.000 31.92233  ? 164 HIS H HD1  1 
ATOM   2446 H HD2  . HIS A 1 168 ? 58.99600 2.77400   9.49300   1.000 32.22306  ? 164 HIS H HD2  1 
ATOM   2447 H HE1  . HIS A 1 168 ? 57.11600 3.51600   12.89700  1.000 33.13438  ? 164 HIS H HE1  1 
ATOM   2448 N N    . THR A 1 169 ? 56.55000 -3.00300  10.28500  1.000 19.40834  ? 165 THR H N    1 
ATOM   2449 C CA   . THR A 1 169 ? 55.94600 -4.15400  9.63300   1.000 18.57772  ? 165 THR H CA   1 
ATOM   2450 C C    . THR A 1 169 ? 54.45400 -3.87300  9.50200   1.000 18.35777  ? 165 THR H C    1 
ATOM   2451 O O    . THR A 1 169 ? 53.76000 -3.71000  10.51200  1.000 17.77777  ? 165 THR H O    1 
ATOM   2452 C CB   . THR A 1 169 ? 56.21900 -5.43400  10.42000  1.000 20.33932  ? 165 THR H CB   1 
ATOM   2453 O OG1  . THR A 1 169 ? 57.63700 -5.64000  10.49500  1.000 19.14718  ? 165 THR H OG1  1 
ATOM   2454 C CG2  . THR A 1 169 ? 55.57400 -6.63300  9.73600   1.000 19.70856  ? 165 THR H CG2  1 
ATOM   2455 H H    . THR A 1 169 ? 56.40500 -2.97200  11.13200  1.000 23.29358  ? 165 THR H H    1 
ATOM   2456 H HA   . THR A 1 169 ? 56.31700 -4.28500  8.74600   1.000 22.29684  ? 165 THR H HA   1 
ATOM   2457 H HB   . THR A 1 169 ? 55.84600 -5.35800  11.31200  1.000 24.41075  ? 165 THR H HB   1 
ATOM   2458 H HG1  . THR A 1 169 ? 57.83400 -6.02500  11.21500  1.000 22.98019  ? 165 THR H HG1  1 
ATOM   2459 H HG21 . THR A 1 169 ? 55.81200 -7.44900  10.20200  1.000 23.65384  ? 165 THR H HG21 1 
ATOM   2460 H HG22 . THR A 1 169 ? 54.60900 -6.53700  9.74000   1.000 23.65384  ? 165 THR H HG22 1 
ATOM   2461 H HG23 . THR A 1 169 ? 55.88000 -6.69400  8.81700   1.000 23.65384  ? 165 THR H HG23 1 
ATOM   2462 N N    . PHE A 1 170 ? 53.97600 -3.77400  8.26100   1.000 15.33655  ? 166 PHE H N    1 
ATOM   2463 C CA   . PHE A 1 170 ? 52.61500 -3.32200  8.01900   1.000 16.87679  ? 166 PHE H CA   1 
ATOM   2464 C C    . PHE A 1 170 ? 51.61400 -4.45200  8.23500   1.000 19.19743  ? 166 PHE H C    1 
ATOM   2465 O O    . PHE A 1 170 ? 51.95700 -5.63000  8.10300   1.000 16.35487  ? 166 PHE H O    1 
ATOM   2466 C CB   . PHE A 1 170 ? 52.48200 -2.78300  6.59500   1.000 17.52721  ? 166 PHE H CB   1 
ATOM   2467 C CG   . PHE A 1 170 ? 53.24300 -1.51500  6.36800   1.000 17.12614  ? 166 PHE H CG   1 
ATOM   2468 C CD1  . PHE A 1 170 ? 52.67100 -0.29200  6.66500   1.000 17.69723  ? 166 PHE H CD1  1 
ATOM   2469 C CD2  . PHE A 1 170 ? 54.54000 -1.54400  5.89100   1.000 17.44806  ? 166 PHE H CD2  1 
ATOM   2470 C CE1  . PHE A 1 170 ? 53.37500 0.88500   6.48000   1.000 16.85683  ? 166 PHE H CE1  1 
ATOM   2471 C CE2  . PHE A 1 170 ? 55.25200 -0.36500  5.69900   1.000 19.68975  ? 166 PHE H CE2  1 
ATOM   2472 C CZ   . PHE A 1 170 ? 54.66600 0.84700   5.99700   1.000 17.94805  ? 166 PHE H CZ   1 
ATOM   2473 H H    . PHE A 1 170 ? 54.42000 -3.96300  7.54900   1.000 18.40743  ? 166 PHE H H    1 
ATOM   2474 H HA   . PHE A 1 170 ? 52.39900 -2.61000  8.64000   1.000 20.25571  ? 166 PHE H HA   1 
ATOM   2475 H HB2  . PHE A 1 170 ? 52.82000 -3.44800  5.97600   1.000 21.03622  ? 166 PHE H HB2  1 
ATOM   2476 H HB3  . PHE A 1 170 ? 51.54600 -2.60600  6.41400   1.000 21.03622  ? 166 PHE H HB3  1 
ATOM   2477 H HD1  . PHE A 1 170 ? 51.80200 -0.26000  6.99300   1.000 21.24025  ? 166 PHE H HD1  1 
ATOM   2478 H HD2  . PHE A 1 170 ? 54.94100 -2.36000  5.69600   1.000 20.94124  ? 166 PHE H HD2  1 
ATOM   2479 H HE1  . PHE A 1 170 ? 52.97800 1.70100   6.68200   1.000 20.23176  ? 166 PHE H HE1  1 
ATOM   2480 H HE2  . PHE A 1 170 ? 56.12100 -0.39400  5.37000   1.000 23.63127  ? 166 PHE H HE2  1 
ATOM   2481 H HZ   . PHE A 1 170 ? 55.14100 1.63800   5.87200   1.000 21.54122  ? 166 PHE H HZ   1 
ATOM   2482 N N    . PRO A 1 171 ? 50.36900 -4.11500  8.57700   1.000 21.77990  ? 167 PRO H N    1 
ATOM   2483 C CA   . PRO A 1 171 ? 49.32200 -5.14100  8.60800   1.000 20.57857  ? 167 PRO H CA   1 
ATOM   2484 C C    . PRO A 1 171 ? 49.20500 -5.83300  7.26200   1.000 21.63985  ? 167 PRO H C    1 
ATOM   2485 O O    . PRO A 1 171 ? 49.41500 -5.23200  6.20500   1.000 18.30692  ? 167 PRO H O    1 
ATOM   2486 C CB   . PRO A 1 171 ? 48.04800 -4.35200  8.93600   1.000 20.98782  ? 167 PRO H CB   1 
ATOM   2487 C CG   . PRO A 1 171 ? 48.52600 -3.10100  9.60300   1.000 24.12039  ? 167 PRO H CG   1 
ATOM   2488 C CD   . PRO A 1 171 ? 49.86400 -2.79000  8.98600   1.000 22.37997  ? 167 PRO H CD   1 
ATOM   2489 H HA   . PRO A 1 171 ? 49.49200 -5.79000  9.30800   1.000 24.69786  ? 167 PRO H HA   1 
ATOM   2490 H HB2  . PRO A 1 171 ? 47.56700 -4.14700  8.11900   1.000 25.18895  ? 167 PRO H HB2  1 
ATOM   2491 H HB3  . PRO A 1 171 ? 47.48500 -4.86900  9.53300   1.000 25.18895  ? 167 PRO H HB3  1 
ATOM   2492 H HG2  . PRO A 1 171 ? 47.89600 -2.38200  9.43700   1.000 28.94804  ? 167 PRO H HG2  1 
ATOM   2493 H HG3  . PRO A 1 171 ? 48.61400 -3.25200  10.55700  1.000 28.94804  ? 167 PRO H HG3  1 
ATOM   2494 H HD2  . PRO A 1 171 ? 49.76300 -2.20700  8.21700   1.000 26.85953  ? 167 PRO H HD2  1 
ATOM   2495 H HD3  . PRO A 1 171 ? 50.45700 -2.38100  9.63600   1.000 26.85953  ? 167 PRO H HD3  1 
ATOM   2496 N N    . ALA A 1 172 ? 48.86000 -7.11300  7.30800   1.000 18.51694  ? 168 ALA H N    1 
ATOM   2497 C CA   . ALA A 1 172 ? 48.60900 -7.84300  6.07900   1.000 20.63951  ? 168 ALA H CA   1 
ATOM   2498 C C    . ALA A 1 172 ? 47.33600 -7.32800  5.42200   1.000 21.82063  ? 168 ALA H C    1 
ATOM   2499 O O    . ALA A 1 172 ? 46.38500 -6.91500  6.09300   1.000 20.50891  ? 168 ALA H O    1 
ATOM   2500 C CB   . ALA A 1 172 ? 48.48300 -9.33900  6.35400   1.000 18.94783  ? 168 ALA H CB   1 
ATOM   2501 H H    . ALA A 1 172 ? 48.76600 -7.57300  8.02900   1.000 22.22390  ? 168 ALA H H    1 
ATOM   2502 H HA   . ALA A 1 172 ? 49.35200 -7.71700  5.46900   1.000 24.77099  ? 168 ALA H HA   1 
ATOM   2503 H HB1  . ALA A 1 172 ? 48.33100 -9.80200  5.51500   1.000 22.74096  ? 168 ALA H HB1  1 
ATOM   2504 H HB2  . ALA A 1 172 ? 49.30400 -9.65600  6.76200   1.000 22.74096  ? 168 ALA H HB2  1 
ATOM   2505 H HB3  . ALA A 1 172 ? 47.73600 -9.48900  6.95400   1.000 22.74096  ? 168 ALA H HB3  1 
ATOM   2506 N N    . VAL A 1 173 ? 47.33400 -7.34800  4.09100   1.000 16.32432  ? 169 VAL H N    1 
ATOM   2507 C CA   . VAL A 1 173 ? 46.15000 -7.07300  3.29100   1.000 19.56833  ? 169 VAL H CA   1 
ATOM   2508 C C    . VAL A 1 173 ? 45.79300 -8.33400  2.51800   1.000 17.82774  ? 169 VAL H C    1 
ATOM   2509 O O    . VAL A 1 173 ? 46.67600 -9.01800  1.98800   1.000 18.43887  ? 169 VAL H O    1 
ATOM   2510 C CB   . VAL A 1 173 ? 46.36400 -5.89400  2.31900   1.000 22.94883  ? 169 VAL H CB   1 
ATOM   2511 C CG1  . VAL A 1 173 ? 46.87900 -4.68100  3.06500   1.000 24.73988  ? 169 VAL H CG1  1 
ATOM   2512 C CG2  . VAL A 1 173 ? 47.31700 -6.28200  1.19400   1.000 24.58976  ? 169 VAL H CG2  1 
ATOM   2513 H H    . VAL A 1 173 ? 48.03000 -7.52300  3.61700   1.000 19.59275  ? 169 VAL H H    1 
ATOM   2514 H HA   . VAL A 1 173 ? 45.41600 -6.84600  3.88400   1.000 23.48556  ? 169 VAL H HA   1 
ATOM   2515 H HB   . VAL A 1 173 ? 45.51100 -5.66400  1.91800   1.000 27.54217  ? 169 VAL H HB   1 
ATOM   2516 H HG11 . VAL A 1 173 ? 46.96600 -3.94200  2.44300   1.000 29.69143  ? 169 VAL H HG11 1 
ATOM   2517 H HG12 . VAL A 1 173 ? 46.24900 -4.45100  3.76600   1.000 29.69143  ? 169 VAL H HG12 1 
ATOM   2518 H HG13 . VAL A 1 173 ? 47.74300 -4.89100  3.45200   1.000 29.69143  ? 169 VAL H HG13 1 
ATOM   2519 H HG21 . VAL A 1 173 ? 47.56800 -5.48300  0.70300   1.000 29.51128  ? 169 VAL H HG21 1 
ATOM   2520 H HG22 . VAL A 1 173 ? 48.10600 -6.69600  1.57700   1.000 29.51128  ? 169 VAL H HG22 1 
ATOM   2521 H HG23 . VAL A 1 173 ? 46.87000 -6.90700  0.60200   1.000 29.51128  ? 169 VAL H HG23 1 
ATOM   2522 N N    . LEU A 1 174 ? 44.49900 -8.63500  2.44500   1.000 17.49844  ? 170 LEU H N    1 
ATOM   2523 C CA   . LEU A 1 174 ? 44.01500 -9.74700  1.63600   1.000 17.15711  ? 170 LEU H CA   1 
ATOM   2524 C C    . LEU A 1 174 ? 43.93500 -9.30000  0.18000   1.000 18.50827  ? 170 LEU H C    1 
ATOM   2525 O O    . LEU A 1 174 ? 43.21800 -8.34700  -0.14200  1.000 19.65801  ? 170 LEU H O    1 
ATOM   2526 C CB   . LEU A 1 174 ? 42.65200 -10.21300 2.14000   1.000 17.36752  ? 170 LEU H CB   1 
ATOM   2527 C CG   . LEU A 1 174 ? 42.04400 -11.43300 1.44700   1.000 18.54850  ? 170 LEU H CG   1 
ATOM   2528 C CD1  . LEU A 1 174 ? 42.81600 -12.70000 1.78400   1.000 17.28847  ? 170 LEU H CD1  1 
ATOM   2529 C CD2  . LEU A 1 174 ? 40.57900 -11.60400 1.81600   1.000 19.85953  ? 170 LEU H CD2  1 
ATOM   2530 H H    . LEU A 1 174 ? 43.87800 -8.20700  2.85900   1.000 21.00170  ? 170 LEU H H    1 
ATOM   2531 H HA   . LEU A 1 174 ? 44.63000 -10.49400 1.69900   1.000 20.59210  ? 170 LEU H HA   1 
ATOM   2532 H HB2  . LEU A 1 174 ? 42.74000 -10.43500 3.08000   1.000 20.84459  ? 170 LEU H HB2  1 
ATOM   2533 H HB3  . LEU A 1 174 ? 42.02500 -9.48100  2.02900   1.000 20.84459  ? 170 LEU H HB3  1 
ATOM   2534 H HG   . LEU A 1 174 ? 42.10100 -11.28800 0.49000   1.000 22.26177  ? 170 LEU H HG   1 
ATOM   2535 H HD11 . LEU A 1 174 ? 42.39400 -13.45400 1.34200   1.000 20.74973  ? 170 LEU H HD11 1 
ATOM   2536 H HD12 . LEU A 1 174 ? 43.73000 -12.60500 1.47500   1.000 20.74973  ? 170 LEU H HD12 1 
ATOM   2537 H HD13 . LEU A 1 174 ? 42.80300 -12.83100 2.74500   1.000 20.74973  ? 170 LEU H HD13 1 
ATOM   2538 H HD21 . LEU A 1 174 ? 40.23000 -12.38900 1.36600   1.000 23.83501  ? 170 LEU H HD21 1 
ATOM   2539 H HD22 . LEU A 1 174 ? 40.50500 -11.71300 2.77700   1.000 23.83501  ? 170 LEU H HD22 1 
ATOM   2540 H HD23 . LEU A 1 174 ? 40.08800 -10.81600 1.53300   1.000 23.83501  ? 170 LEU H HD23 1 
ATOM   2541 N N    . GLN A 1 175 ? 44.67200 -9.97900  -0.69500  1.000 16.88634  ? 171 GLN H N    1 
ATOM   2542 C CA   . GLN A 1 175 ? 44.67000 -9.64800  -2.11000  1.000 19.20774  ? 171 GLN H CA   1 
ATOM   2543 C C    . GLN A 1 175 ? 43.45500 -10.25900 -2.80600  1.000 21.16097  ? 171 GLN H C    1 
ATOM   2544 O O    . GLN A 1 175 ? 42.80800 -11.17700 -2.29800  1.000 18.86674  ? 171 GLN H O    1 
ATOM   2545 C CB   . GLN A 1 175 ? 45.95100 -10.14600 -2.77700  1.000 17.47641  ? 171 GLN H CB   1 
ATOM   2546 C CG   . GLN A 1 175 ? 47.22800 -9.64300  -2.12200  1.000 18.87802  ? 171 GLN H CG   1 
ATOM   2547 C CD   . GLN A 1 175 ? 48.46500 -10.35600 -2.63300  1.000 20.16906  ? 171 GLN H CD   1 
ATOM   2548 O OE1  . GLN A 1 175 ? 49.18800 -9.83300  -3.48400  1.000 22.30879  ? 171 GLN H OE1  1 
ATOM   2549 N NE2  . GLN A 1 175 ? 48.71000 -11.56300 -2.12100  1.000 19.02725  ? 171 GLN H NE2  1 
ATOM   2550 H H    . GLN A 1 175 ? 45.18500 -10.63800 -0.49000  1.000 20.26717  ? 171 GLN H H    1 
ATOM   2551 H HA   . GLN A 1 175 ? 44.62500 -8.68400  -2.21200  1.000 23.05286  ? 171 GLN H HA   1 
ATOM   2552 H HB2  . GLN A 1 175 ? 45.96300 -11.11500 -2.74100  1.000 20.97526  ? 171 GLN H HB2  1 
ATOM   2553 H HB3  . GLN A 1 175 ? 45.95600 -9.84800  -3.70000  1.000 20.97526  ? 171 GLN H HB3  1 
ATOM   2554 H HG2  . GLN A 1 175 ? 47.32900 -8.69700  -2.30900  1.000 22.65720  ? 171 GLN H HG2  1 
ATOM   2555 H HG3  . GLN A 1 175 ? 47.17200 -9.78800  -1.16500  1.000 22.65720  ? 171 GLN H HG3  1 
ATOM   2556 H HE21 . GLN A 1 175 ? 48.17900 -11.89700 -1.53300  1.000 22.83627  ? 171 GLN H HE21 1 
ATOM   2557 H HE22 . GLN A 1 175 ? 49.40000 -12.00700 -2.37900  1.000 22.83627  ? 171 GLN H HE22 1 
ATOM   2558 N N    . SER A 1 176 ? 43.15900 -9.74100  -4.00200  1.000 19.25811  ? 172 SER H N    1 
ATOM   2559 C CA   . SER A 1 176 ? 42.02100 -10.24900 -4.76100  1.000 20.24913  ? 172 SER H CA   1 
ATOM   2560 C C    . SER A 1 176 ? 42.14600 -11.74200 -5.04100  1.000 18.77808  ? 172 SER H C    1 
ATOM   2561 O O    . SER A 1 176 ? 41.14500 -12.38700 -5.36900  1.000 18.69698  ? 172 SER H O    1 
ATOM   2562 C CB   . SER A 1 176 ? 41.87200 -9.46700  -6.07100  1.000 20.27802  ? 172 SER H CB   1 
ATOM   2563 O OG   . SER A 1 176 ? 42.93100 -9.75100  -6.96900  1.000 25.60028  ? 172 SER H OG   1 
ATOM   2564 H H    . SER A 1 176 ? 43.59400 -9.10700  -4.38600  1.000 23.11330  ? 172 SER H H    1 
ATOM   2565 H HA   . SER A 1 176 ? 41.21000 -10.11100 -4.24700  1.000 24.30252  ? 172 SER H HA   1 
ATOM   2566 H HB2  . SER A 1 176 ? 41.03300 -9.71500  -6.48900  1.000 24.33719  ? 172 SER H HB2  1 
ATOM   2567 H HB3  . SER A 1 176 ? 41.87600 -8.51800  -5.87200  1.000 24.33719  ? 172 SER H HB3  1 
ATOM   2568 H HG   . SER A 1 176 ? 43.66900 -9.67600  -6.57500  1.000 30.72390  ? 172 SER H HG   1 
ATOM   2569 N N    . SER A 1 177 ? 43.34400 -12.30600 -4.89800  1.000 17.61760  ? 173 SER H N    1 
ATOM   2570 C CA   . SER A 1 177 ? 43.55500 -13.73600 -5.08100  1.000 19.07864  ? 173 SER H CA   1 
ATOM   2571 C C    . SER A 1 177 ? 43.13200 -14.56700 -3.87800  1.000 19.20812  ? 173 SER H C    1 
ATOM   2572 O O    . SER A 1 177 ? 43.17700 -15.80000 -3.95500  1.000 16.64619  ? 173 SER H O    1 
ATOM   2573 C CB   . SER A 1 177 ? 45.03200 -13.99800 -5.35800  1.000 19.09791  ? 173 SER H CB   1 
ATOM   2574 O OG   . SER A 1 177 ? 45.81000 -13.45800 -4.30200  1.000 18.49807  ? 173 SER H OG   1 
ATOM   2575 H H    . SER A 1 177 ? 44.05900 -11.87500 -4.69300  1.000 21.14469  ? 173 SER H H    1 
ATOM   2576 H HA   . SER A 1 177 ? 43.03000 -14.02700 -5.84300  1.000 22.89794  ? 173 SER H HA   1 
ATOM   2577 H HB2  . SER A 1 177 ? 45.18400 -14.95400 -5.41300  1.000 22.92106  ? 173 SER H HB2  1 
ATOM   2578 H HB3  . SER A 1 177 ? 45.28300 -13.57300 -6.19300  1.000 22.92106  ? 173 SER H HB3  1 
ATOM   2579 H HG   . SER A 1 177 ? 46.61800 -13.42000 -4.53100  1.000 22.20126  ? 173 SER H HG   1 
ATOM   2580 N N    . GLY A 1 178 ? 42.73700 -13.93500 -2.77500  1.000 17.83779  ? 174 GLY H N    1 
ATOM   2581 C CA   . GLY A 1 178 ? 42.46400 -14.65600 -1.54700  1.000 17.52803  ? 174 GLY H CA   1 
ATOM   2582 C C    . GLY A 1 178 ? 43.68500 -14.98100 -0.71800  1.000 17.12769  ? 174 GLY H C    1 
ATOM   2583 O O    . GLY A 1 178 ? 43.56900 -15.71600 0.27100   1.000 18.79868  ? 174 GLY H O    1 
ATOM   2584 H H    . GLY A 1 178 ? 42.62000 -13.08500 -2.71800  1.000 21.40891  ? 174 GLY H H    1 
ATOM   2585 H HA2  . GLY A 1 178 ? 41.86800 -14.12100 -1.00000  1.000 21.03720  ? 174 GLY H HA2  1 
ATOM   2586 H HA3  . GLY A 1 178 ? 42.02500 -15.49200 -1.76900  1.000 21.03720  ? 174 GLY H HA3  1 
ATOM   2587 N N    . LEU A 1 179 ? 44.85200 -14.47400 -1.10100  1.000 15.76759  ? 175 LEU H N    1 
ATOM   2588 C CA   . LEU A 1 179 ? 46.10200 -14.69500 -0.39600  1.000 13.85523  ? 175 LEU H CA   1 
ATOM   2589 C C    . LEU A 1 179 ? 46.58100 -13.38300 0.20200   1.000 16.30814  ? 175 LEU H C    1 
ATOM   2590 O O    . LEU A 1 179 ? 46.30900 -12.30600 -0.33600  1.000 15.41719  ? 175 LEU H O    1 
ATOM   2591 C CB   . LEU A 1 179 ? 47.18400 -15.22800 -1.33100  1.000 15.34678  ? 175 LEU H CB   1 
ATOM   2592 C CG   . LEU A 1 179 ? 46.85200 -16.46700 -2.15300  1.000 20.55059  ? 175 LEU H CG   1 
ATOM   2593 C CD1  . LEU A 1 179 ? 47.88800 -16.64900 -3.24400  1.000 19.68818  ? 175 LEU H CD1  1 
ATOM   2594 C CD2  . LEU A 1 179 ? 46.79700 -17.68200 -1.27100  1.000 16.72711  ? 175 LEU H CD2  1 
ATOM   2595 H H    . LEU A 1 179 ? 44.94600 -13.97700 -1.79700  1.000 18.92467  ? 175 LEU H H    1 
ATOM   2596 H HA   . LEU A 1 179 ? 45.96100 -15.34500 0.31100   1.000 16.62985  ? 175 LEU H HA   1 
ATOM   2597 H HB2  . LEU A 1 179 ? 47.40600 -14.52300 -1.96000  1.000 18.41971  ? 175 LEU H HB2  1 
ATOM   2598 H HB3  . LEU A 1 179 ? 47.96100 -15.44700 -0.79200  1.000 18.41971  ? 175 LEU H HB3  1 
ATOM   2599 H HG   . LEU A 1 179 ? 45.98100 -16.35900 -2.56700  1.000 24.66428  ? 175 LEU H HG   1 
ATOM   2600 H HD11 . LEU A 1 179 ? 47.67500 -17.44700 -3.75300  1.000 23.62939  ? 175 LEU H HD11 1 
ATOM   2601 H HD12 . LEU A 1 179 ? 47.87500 -15.87300 -3.82600  1.000 23.62939  ? 175 LEU H HD12 1 
ATOM   2602 H HD13 . LEU A 1 179 ? 48.76300 -16.74200 -2.83600  1.000 23.62939  ? 175 LEU H HD13 1 
ATOM   2603 H HD21 . LEU A 1 179 ? 46.64500 -18.46600 -1.82100  1.000 20.07611  ? 175 LEU H HD21 1 
ATOM   2604 H HD22 . LEU A 1 179 ? 47.64100 -17.76700 -0.79900  1.000 20.07611  ? 175 LEU H HD22 1 
ATOM   2605 H HD23 . LEU A 1 179 ? 46.07200 -17.57800 -0.63500  1.000 20.07611  ? 175 LEU H HD23 1 
ATOM   2606 N N    . TYR A 1 180 ? 47.32800 -13.48200 1.29300   1.000 14.78706  ? 176 TYR H N    1 
ATOM   2607 C CA   . TYR A 1 180 ? 47.77600 -12.30300 2.01200   1.000 14.73798  ? 176 TYR H CA   1 
ATOM   2608 C C    . TYR A 1 180 ? 49.10300 -11.78800 1.46300   1.000 14.86734  ? 176 TYR H C    1 
ATOM   2609 O O    . TYR A 1 180 ? 49.89200 -12.51800 0.85700   1.000 14.16623  ? 176 TYR H O    1 
ATOM   2610 C CB   . TYR A 1 180 ? 47.91000 -12.60500 3.50800   1.000 15.94800  ? 176 TYR H CB   1 
ATOM   2611 C CG   . TYR A 1 180 ? 46.58200 -12.83500 4.19400   1.000 15.24702  ? 176 TYR H CG   1 
ATOM   2612 C CD1  . TYR A 1 180 ? 45.79500 -11.76600 4.60000   1.000 17.84813  ? 176 TYR H CD1  1 
ATOM   2613 C CD2  . TYR A 1 180 ? 46.11200 -14.11800 4.42900   1.000 14.91660  ? 176 TYR H CD2  1 
ATOM   2614 C CE1  . TYR A 1 180 ? 44.57600 -11.97000 5.22600   1.000 19.06887  ? 176 TYR H CE1  1 
ATOM   2615 C CE2  . TYR A 1 180 ? 44.89600 -14.33200 5.04700   1.000 17.76872  ? 176 TYR H CE2  1 
ATOM   2616 C CZ   . TYR A 1 180 ? 44.13400 -13.25600 5.44500   1.000 19.07919  ? 176 TYR H CZ   1 
ATOM   2617 O OH   . TYR A 1 180 ? 42.92600 -13.47000 6.06300   1.000 22.91009  ? 176 TYR H OH   1 
ATOM   2618 H H    . TYR A 1 180 ? 47.58900 -14.22500 1.63600   1.000 17.74805  ? 176 TYR H H    1 
ATOM   2619 H HA   . TYR A 1 180 ? 47.11900 -11.59900 1.89900   1.000 17.68915  ? 176 TYR H HA   1 
ATOM   2620 H HB2  . TYR A 1 180 ? 48.44500 -13.40700 3.61900   1.000 19.14117  ? 176 TYR H HB2  1 
ATOM   2621 H HB3  . TYR A 1 180 ? 48.34300 -11.85400 3.94200   1.000 19.14117  ? 176 TYR H HB3  1 
ATOM   2622 H HD1  . TYR A 1 180 ? 46.09200 -10.89700 4.45000   1.000 21.42132  ? 176 TYR H HD1  1 
ATOM   2623 H HD2  . TYR A 1 180 ? 46.62400 -14.84800 4.16500   1.000 17.90349  ? 176 TYR H HD2  1 
ATOM   2624 H HE1  . TYR A 1 180 ? 44.06100 -11.24500 5.49500   1.000 22.88621  ? 176 TYR H HE1  1 
ATOM   2625 H HE2  . TYR A 1 180 ? 44.59200 -15.19900 5.19400   1.000 21.32604  ? 176 TYR H HE2  1 
ATOM   2626 H HH   . TYR A 1 180 ? 42.60000 -12.73900 6.31800   1.000 27.49568  ? 176 TYR H HH   1 
ATOM   2627 N N    . SER A 1 181 ? 49.32900 -10.49700 1.67900   1.000 13.19589  ? 177 SER H N    1 
ATOM   2628 C CA   . SER A 1 181 ? 50.59800 -9.85500  1.38400   1.000 14.84565  ? 177 SER H CA   1 
ATOM   2629 C C    . SER A 1 181 ? 50.87000 -8.82300  2.46600   1.000 15.69672  ? 177 SER H C    1 
ATOM   2630 O O    . SER A 1 181 ? 49.94100 -8.22500  3.01200   1.000 14.62671  ? 177 SER H O    1 
ATOM   2631 C CB   . SER A 1 181 ? 50.57300 -9.19000  0.00600   1.000 16.36655  ? 177 SER H CB   1 
ATOM   2632 O OG   . SER A 1 181 ? 51.77400 -8.49400  -0.24800  1.000 24.37165  ? 177 SER H OG   1 
ATOM   2633 H H    . SER A 1 181 ? 48.74400 -9.95800  2.00700   1.000 15.83864  ? 177 SER H H    1 
ATOM   2634 H HA   . SER A 1 181 ? 51.32000 -10.50300 1.38900   1.000 17.81835  ? 177 SER H HA   1 
ATOM   2635 H HB2  . SER A 1 181 ? 50.45800 -9.87500  -0.67100  1.000 19.64344  ? 177 SER H HB2  1 
ATOM   2636 H HB3  . SER A 1 181 ? 49.83400 -8.56300  -0.02700  1.000 19.64344  ? 177 SER H HB3  1 
ATOM   2637 H HG   . SER A 1 181 ? 52.43300 -8.98500  -0.07400  1.000 29.24955  ? 177 SER H HG   1 
ATOM   2638 N N    . LEU A 1 182 ? 52.14700 -8.63700  2.79200   1.000 15.19594  ? 178 LEU H N    1 
ATOM   2639 C CA   . LEU A 1 182 ? 52.54500 -7.52200  3.64100   1.000 18.66890  ? 178 LEU H CA   1 
ATOM   2640 C C    . LEU A 1 182 ? 54.00900 -7.20400  3.37900   1.000 18.04812  ? 178 LEU H C    1 
ATOM   2641 O O    . LEU A 1 182 ? 54.76200 -8.02900  2.85400   1.000 16.66691  ? 178 LEU H O    1 
ATOM   2642 C CB   . LEU A 1 182 ? 52.31500 -7.81100  5.13100   1.000 20.24974  ? 178 LEU H CB   1 
ATOM   2643 C CG   . LEU A 1 182 ? 53.17100 -8.84900  5.86200   1.000 18.08877  ? 178 LEU H CG   1 
ATOM   2644 C CD1  . LEU A 1 182 ? 54.58900 -8.36300  6.12200   1.000 19.83896  ? 178 LEU H CD1  1 
ATOM   2645 C CD2  . LEU A 1 182 ? 52.51400 -9.23300  7.18500   1.000 22.51042  ? 178 LEU H CD2  1 
ATOM   2646 H H    . LEU A 1 182 ? 52.79500 -9.14000  2.53600   1.000 18.23870  ? 178 LEU H H    1 
ATOM   2647 H HA   . LEU A 1 182 ? 52.01400 -6.74600  3.40300   1.000 22.40626  ? 178 LEU H HA   1 
ATOM   2648 H HB2  . LEU A 1 182 ? 52.44300 -6.97500  5.60700   1.000 24.30326  ? 178 LEU H HB2  1 
ATOM   2649 H HB3  . LEU A 1 182 ? 51.39600 -8.10800  5.22500   1.000 24.30326  ? 178 LEU H HB3  1 
ATOM   2650 H HG   . LEU A 1 182 ? 53.23800 -9.62800  5.28800   1.000 21.71010  ? 178 LEU H HG   1 
ATOM   2651 H HD11 . LEU A 1 182 ? 54.96500 -8.86700  6.86000   1.000 23.81032  ? 178 LEU H HD11 1 
ATOM   2652 H HD12 . LEU A 1 182 ? 55.12100 -8.50100  5.32200   1.000 23.81032  ? 178 LEU H HD12 1 
ATOM   2653 H HD13 . LEU A 1 182 ? 54.56400 -7.41900  6.34400   1.000 23.81032  ? 178 LEU H HD13 1 
ATOM   2654 H HD21 . LEU A 1 182 ? 53.06800 -9.89100  7.63400   1.000 27.01607  ? 178 LEU H HD21 1 
ATOM   2655 H HD22 . LEU A 1 182 ? 52.42800 -8.44100  7.73800   1.000 27.01607  ? 178 LEU H HD22 1 
ATOM   2656 H HD23 . LEU A 1 182 ? 51.63700 -9.60700  7.00500   1.000 27.01607  ? 178 LEU H HD23 1 
ATOM   2657 N N    . SER A 1 183 ? 54.39400 -5.98900  3.75700   1.000 15.95714  ? 179 SER H N    1 
ATOM   2658 C CA   . SER A 1 183 ? 55.77200 -5.53800  3.67900   1.000 16.95754  ? 179 SER H CA   1 
ATOM   2659 C C    . SER A 1 183 ? 56.27400 -5.20400  5.07600   1.000 15.81650  ? 179 SER H C    1 
ATOM   2660 O O    . SER A 1 183 ? 55.51000 -4.76400  5.94100   1.000 17.33746  ? 179 SER H O    1 
ATOM   2661 C CB   . SER A 1 183 ? 55.91200 -4.30900  2.77300   1.000 18.51857  ? 179 SER H CB   1 
ATOM   2662 O OG   . SER A 1 183 ? 55.75500 -4.65100  1.40600   1.000 23.23141  ? 179 SER H OG   1 
ATOM   2663 H H    . SER A 1 183 ? 53.85800 -5.39400  4.06900   1.000 19.15214  ? 179 SER H H    1 
ATOM   2664 H HA   . SER A 1 183 ? 56.32500 -6.24400  3.31000   1.000 20.35262  ? 179 SER H HA   1 
ATOM   2665 H HB2  . SER A 1 183 ? 55.23100 -3.66200  3.01400   1.000 22.22585  ? 179 SER H HB2  1 
ATOM   2666 H HB3  . SER A 1 183 ? 56.79400 -3.92500  2.90000   1.000 22.22585  ? 179 SER H HB3  1 
ATOM   2667 H HG   . SER A 1 183 ? 54.94400 -4.78900  1.23700   1.000 27.88127  ? 179 SER H HG   1 
ATOM   2668 N N    . SER A 1 184 ? 57.56300 -5.44700  5.29300   1.000 15.48696  ? 180 SER H N    1 
ATOM   2669 C CA   . SER A 1 184 ? 58.28200 -4.97500  6.46800   1.000 18.15807  ? 180 SER H CA   1 
ATOM   2670 C C    . SER A 1 184 ? 59.43800 -4.11600  5.98300   1.000 16.49782  ? 180 SER H C    1 
ATOM   2671 O O    . SER A 1 184 ? 60.18000 -4.52200  5.08200   1.000 17.33784  ? 180 SER H O    1 
ATOM   2672 C CB   . SER A 1 184 ? 58.80000 -6.13100  7.32100   1.000 19.19964  ? 180 SER H CB   1 
ATOM   2673 O OG   . SER A 1 184 ? 59.48200 -5.64800  8.46700   1.000 18.44853  ? 180 SER H OG   1 
ATOM   2674 H H    . SER A 1 184 ? 58.05800 -5.89800  4.75400   1.000 18.58792  ? 180 SER H H    1 
ATOM   2675 H HA   . SER A 1 184 ? 57.69400 -4.44700  7.03000   1.000 21.79326  ? 180 SER H HA   1 
ATOM   2676 H HB2  . SER A 1 184 ? 58.04900 -6.67400  7.60600   1.000 23.04314  ? 180 SER H HB2  1 
ATOM   2677 H HB3  . SER A 1 184 ? 59.41300 -6.66400  6.79100   1.000 23.04314  ? 180 SER H HB3  1 
ATOM   2678 H HG   . SER A 1 184 ? 58.92800 -5.43100  9.06000   1.000 22.14181  ? 180 SER H HG   1 
ATOM   2679 N N    . VAL A 1 185 ? 59.57700 -2.92500  6.55600   1.000 19.09883  ? 181 VAL H N    1 
ATOM   2680 C CA   . VAL A 1 185 ? 60.58900 -1.97900  6.11700   1.000 18.27907  ? 181 VAL H CA   1 
ATOM   2681 C C    . VAL A 1 185 ? 61.34600 -1.47700  7.33300   1.000 19.84864  ? 181 VAL H C    1 
ATOM   2682 O O    . VAL A 1 185 ? 60.85900 -1.51800  8.46500   1.000 19.35715  ? 181 VAL H O    1 
ATOM   2683 C CB   . VAL A 1 185 ? 59.97900 -0.79800  5.33300   1.000 18.08808  ? 181 VAL H CB   1 
ATOM   2684 C CG1  . VAL A 1 185 ? 59.18600 -1.31400  4.14400   1.000 17.73741  ? 181 VAL H CG1  1 
ATOM   2685 C CG2  . VAL A 1 185 ? 59.10900 0.05100   6.24800   1.000 18.34801  ? 181 VAL H CG2  1 
ATOM   2686 H H    . VAL A 1 185 ? 59.09100 -2.64200  7.20700   1.000 22.92217  ? 181 VAL H H    1 
ATOM   2687 H HA   . VAL A 1 185 ? 61.22000 -2.43200  5.53500   1.000 21.93846  ? 181 VAL H HA   1 
ATOM   2688 H HB   . VAL A 1 185 ? 60.69100 -0.23200  4.99500   1.000 21.70927  ? 181 VAL H HB   1 
ATOM   2689 H HG11 . VAL A 1 185 ? 58.85800 -0.55900  3.63100   1.000 21.28846  ? 181 VAL H HG11 1 
ATOM   2690 H HG12 . VAL A 1 185 ? 59.76600 -1.86300  3.59300   1.000 21.28846  ? 181 VAL H HG12 1 
ATOM   2691 H HG13 . VAL A 1 185 ? 58.44000 -1.84300  4.46800   1.000 21.28846  ? 181 VAL H HG13 1 
ATOM   2692 H HG21 . VAL A 1 185 ? 58.61700 0.69100   5.71100   1.000 22.02119  ? 181 VAL H HG21 1 
ATOM   2693 H HG22 . VAL A 1 185 ? 58.49200 -0.52800  6.72200   1.000 22.02119  ? 181 VAL H HG22 1 
ATOM   2694 H HG23 . VAL A 1 185 ? 59.67800 0.51700   6.88100   1.000 22.02119  ? 181 VAL H HG23 1 
ATOM   2695 N N    . VAL A 1 186 ? 62.56100 -1.00900  7.08800   1.000 20.93849  ? 182 VAL H N    1 
ATOM   2696 C CA   . VAL A 1 186 ? 63.39200 -0.42400  8.12800   1.000 21.03900  ? 182 VAL H CA   1 
ATOM   2697 C C    . VAL A 1 186 ? 64.18400 0.71700   7.51200   1.000 21.52816  ? 182 VAL H C    1 
ATOM   2698 O O    . VAL A 1 186 ? 64.69300 0.60000   6.39100   1.000 21.80586  ? 182 VAL H O    1 
ATOM   2699 C CB   . VAL A 1 186 ? 64.32200 -1.47300  8.77300   1.000 22.17966  ? 182 VAL H CB   1 
ATOM   2700 C CG1  . VAL A 1 186 ? 65.23800 -2.07900  7.73700   1.000 20.54815  ? 182 VAL H CG1  1 
ATOM   2701 C CG2  . VAL A 1 186 ? 65.12500 -0.85700  9.91200   1.000 22.29830  ? 182 VAL H CG2  1 
ATOM   2702 H H    . VAL A 1 186 ? 62.93300 -1.02000  6.31300   1.000 25.12976  ? 182 VAL H H    1 
ATOM   2703 H HA   . VAL A 1 186 ? 62.83000 -0.05900  8.83000   1.000 25.25037  ? 182 VAL H HA   1 
ATOM   2704 H HB   . VAL A 1 186 ? 63.77600 -2.18400  9.14500   1.000 26.61916  ? 182 VAL H HB   1 
ATOM   2705 H HG11 . VAL A 1 186 ? 65.75700 -2.78800  8.15000   1.000 24.66135  ? 182 VAL H HG11 1 
ATOM   2706 H HG12 . VAL A 1 186 ? 64.70200 -2.44000  7.01300   1.000 24.66135  ? 182 VAL H HG12 1 
ATOM   2707 H HG13 . VAL A 1 186 ? 65.83100 -1.39000  7.39800   1.000 24.66135  ? 182 VAL H HG13 1 
ATOM   2708 H HG21 . VAL A 1 186 ? 65.66300 -1.54800  10.32900  1.000 26.76153  ? 182 VAL H HG21 1 
ATOM   2709 H HG22 . VAL A 1 186 ? 65.69900 -0.16200  9.55400   1.000 26.76153  ? 182 VAL H HG22 1 
ATOM   2710 H HG23 . VAL A 1 186 ? 64.51200 -0.47800  10.56200  1.000 26.76153  ? 182 VAL H HG23 1 
ATOM   2711 N N    . THR A 1 187 ? 64.26900 1.82800   8.23100   1.000 22.37699  ? 183 THR H N    1 
ATOM   2712 C CA   . THR A 1 187 ? 65.10700 2.94800   7.83100   1.000 25.22760  ? 183 THR H CA   1 
ATOM   2713 C C    . THR A 1 187 ? 66.44600 2.82700   8.54300   1.000 27.53789  ? 183 THR H C    1 
ATOM   2714 O O    . THR A 1 187 ? 66.49400 2.61800   9.76000   1.000 27.56815  ? 183 THR H O    1 
ATOM   2715 C CB   . THR A 1 187 ? 64.44400 4.28700   8.15100   1.000 24.83686  ? 183 THR H CB   1 
ATOM   2716 O OG1  . THR A 1 187 ? 63.94900 4.27900   9.49400   1.000 30.84987  ? 183 THR H OG1  1 
ATOM   2717 C CG2  . THR A 1 187 ? 63.29300 4.54500   7.19400   1.000 27.28918  ? 183 THR H CG2  1 
ATOM   2718 H H    . THR A 1 187 ? 63.84300 1.95900   8.96600   1.000 26.85595  ? 183 THR H H    1 
ATOM   2719 H HA   . THR A 1 187 ? 65.25500 2.92300   6.87300   1.000 30.27670  ? 183 THR H HA   1 
ATOM   2720 H HB   . THR A 1 187 ? 65.09500 5.00000   8.05700   1.000 29.80781  ? 183 THR H HB   1 
ATOM   2721 H HG1  . THR A 1 187 ? 63.17300 3.95900   9.51300   1.000 37.02341  ? 183 THR H HG1  1 
ATOM   2722 H HG21 . THR A 1 187 ? 62.89800 5.41200   7.37700   1.000 32.75059  ? 183 THR H HG21 1 
ATOM   2723 H HG22 . THR A 1 187 ? 63.61400 4.53200   6.27900   1.000 32.75059  ? 183 THR H HG22 1 
ATOM   2724 H HG23 . THR A 1 187 ? 62.61400 3.86100   7.29900   1.000 32.75059  ? 183 THR H HG23 1 
ATOM   2725 N N    . VAL A 1 188 ? 67.52900 2.93100   7.77700   1.000 27.63730  ? 184 VAL H N    1 
ATOM   2726 C CA   . VAL A 1 188 ? 68.87900 2.82500   8.31300   1.000 30.28722  ? 184 VAL H CA   1 
ATOM   2727 C C    . VAL A 1 188 ? 69.71100 3.95900   7.73900   1.000 32.96807  ? 184 VAL H C    1 
ATOM   2728 O O    . VAL A 1 188 ? 69.37200 4.52400   6.68300   1.000 33.11833  ? 184 VAL H O    1 
ATOM   2729 C CB   . VAL A 1 188 ? 69.52200 1.45700   7.97800   1.000 29.10657  ? 184 VAL H CB   1 
ATOM   2730 C CG1  . VAL A 1 188 ? 68.63100 0.31800   8.45600   1.000 28.29792  ? 184 VAL H CG1  1 
ATOM   2731 C CG2  . VAL A 1 188 ? 69.78800 1.35400   6.48100   1.000 32.23907  ? 184 VAL H CG2  1 
ATOM   2732 H H    . VAL A 1 188 ? 67.50600 3.06600   6.92800   1.000 33.16833  ? 184 VAL H H    1 
ATOM   2733 H HA   . VAL A 1 188 ? 68.84600 2.92200   9.27700   1.000 36.34823  ? 184 VAL H HA   1 
ATOM   2734 H HB   . VAL A 1 188 ? 70.37200 1.38200   8.44000   1.000 34.93146  ? 184 VAL H HB   1 
ATOM   2735 H HG11 . VAL A 1 188 ? 69.02800 -0.52600  8.18900   1.000 33.96108  ? 184 VAL H HG11 1 
ATOM   2736 H HG12 . VAL A 1 188 ? 68.55900 0.35800   9.42200   1.000 33.96108  ? 184 VAL H HG12 1 
ATOM   2737 H HG13 . VAL A 1 188 ? 67.75400 0.41300   8.05400   1.000 33.96108  ? 184 VAL H HG13 1 
ATOM   2738 H HG21 . VAL A 1 188 ? 70.02500 0.43900   6.26500   1.000 38.69045  ? 184 VAL H HG21 1 
ATOM   2739 H HG22 . VAL A 1 188 ? 68.98600 1.61100   5.99900   1.000 38.69045  ? 184 VAL H HG22 1 
ATOM   2740 H HG23 . VAL A 1 188 ? 70.51800 1.94900   6.24800   1.000 38.69045  ? 184 VAL H HG23 1 
ATOM   2741 N N    . PRO A 1 189 ? 70.80900 4.32200   8.39800   1.000 35.81846  ? 185 PRO H N    1 
ATOM   2742 C CA   . PRO A 1 189 ? 71.75300 5.26700   7.78800   1.000 35.19788  ? 185 PRO H CA   1 
ATOM   2743 C C    . PRO A 1 189 ? 72.30800 4.70800   6.48500   1.000 35.34862  ? 185 PRO H C    1 
ATOM   2744 O O    . PRO A 1 189 ? 72.73300 3.55300   6.41700   1.000 35.63827  ? 185 PRO H O    1 
ATOM   2745 C CB   . PRO A 1 189 ? 72.84400 5.43000   8.85400   1.000 34.26780  ? 185 PRO H CB   1 
ATOM   2746 C CG   . PRO A 1 189 ? 72.68100 4.26500   9.77100   1.000 39.35877  ? 185 PRO H CG   1 
ATOM   2747 C CD   . PRO A 1 189 ? 71.22100 3.92900   9.75800   1.000 35.72845  ? 185 PRO H CD   1 
ATOM   2748 H HA   . PRO A 1 189 ? 71.33100 6.12600   7.62800   1.000 42.24103  ? 185 PRO H HA   1 
ATOM   2749 H HB2  . PRO A 1 189 ? 73.71800 5.41800   8.43300   1.000 41.12493  ? 185 PRO H HB2  1 
ATOM   2750 H HB3  . PRO A 1 189 ? 72.71600 6.26500   9.33000   1.000 41.12493  ? 185 PRO H HB3  1 
ATOM   2751 H HG2  . PRO A 1 189 ? 73.20700 3.51800   9.44600   1.000 47.23409  ? 185 PRO H HG2  1 
ATOM   2752 H HG3  . PRO A 1 189 ? 72.96900 4.51000   10.66400  1.000 47.23409  ? 185 PRO H HG3  1 
ATOM   2753 H HD2  . PRO A 1 189 ? 71.08200 2.98000   9.90300   1.000 42.87771  ? 185 PRO H HD2  1 
ATOM   2754 H HD3  . PRO A 1 189 ? 70.74200 4.44100   10.42800  1.000 42.87771  ? 185 PRO H HD3  1 
ATOM   2755 N N    . SER A 1 190 ? 72.30300 5.54500   5.44500   1.000 34.46818  ? 186 SER H N    1 
ATOM   2756 C CA   . SER A 1 190 ? 72.67600 5.08000   4.11600   1.000 33.87777  ? 186 SER H CA   1 
ATOM   2757 C C    . SER A 1 190 ? 74.15000 4.72300   4.00800   1.000 36.10814  ? 186 SER H C    1 
ATOM   2758 O O    . SER A 1 190 ? 74.52300 3.96400   3.10800   1.000 40.79947  ? 186 SER H O    1 
ATOM   2759 C CB   . SER A 1 190 ? 72.33300 6.14200   3.07100   1.000 35.66896  ? 186 SER H CB   1 
ATOM   2760 O OG   . SER A 1 190 ? 72.72500 7.42900   3.51200   1.000 39.89950  ? 186 SER H OG   1 
ATOM   2761 H H    . SER A 1 190 ? 72.08900 6.37700   5.48600   1.000 41.36539  ? 186 SER H H    1 
ATOM   2762 H HA   . SER A 1 190 ? 72.16200 4.28000   3.92100   1.000 40.65690  ? 186 SER H HA   1 
ATOM   2763 H HB2  . SER A 1 190 ? 72.79900 5.93500   2.24600   1.000 42.80632  ? 186 SER H HB2  1 
ATOM   2764 H HB3  . SER A 1 190 ? 71.37500 6.13800   2.92000   1.000 42.80632  ? 186 SER H HB3  1 
ATOM   2765 H HG   . SER A 1 190 ? 72.47400 8.01000   2.96000   1.000 47.88297  ? 186 SER H HG   1 
ATOM   2766 N N    . SER A 1 191 ? 75.00000 5.25400   4.88600   1.000 35.78819  ? 187 SER H N    1 
ATOM   2767 C CA   . SER A 1 191 ? 76.41300 4.90300   4.81900   1.000 40.34948  ? 187 SER H CA   1 
ATOM   2768 C C    . SER A 1 191 ? 76.66500 3.46200   5.24300   1.000 40.76801  ? 187 SER H C    1 
ATOM   2769 O O    . SER A 1 191 ? 77.70000 2.89400   4.87800   1.000 42.59924  ? 187 SER H O    1 
ATOM   2770 C CB   . SER A 1 191 ? 77.23700 5.86100   5.68200   1.000 36.73717  ? 187 SER H CB   1 
ATOM   2771 O OG   . SER A 1 191 ? 76.68300 6.00600   6.97800   1.000 40.25005  ? 187 SER H OG   1 
ATOM   2772 H H    . SER A 1 191 ? 74.78800 5.80400   5.51200   1.000 42.94940  ? 187 SER H H    1 
ATOM   2773 H HA   . SER A 1 191 ? 76.71700 5.00200   3.90300   1.000 48.42295  ? 187 SER H HA   1 
ATOM   2774 H HB2  . SER A 1 191 ? 78.13800 5.51000   5.76500   1.000 44.08818  ? 187 SER H HB2  1 
ATOM   2775 H HB3  . SER A 1 191 ? 77.25800 6.73000   5.25200   1.000 44.08818  ? 187 SER H HB3  1 
ATOM   2776 H HG   . SER A 1 191 ? 76.02800 6.53100   6.95300   1.000 48.30363  ? 187 SER H HG   1 
ATOM   2777 N N    . SER A 1 192 ? 75.73800 2.85500   5.98200   1.000 42.55910  ? 188 SER H N    1 
ATOM   2778 C CA   . SER A 1 192 ? 75.91500 1.49400   6.46900   1.000 42.42831  ? 188 SER H CA   1 
ATOM   2779 C C    . SER A 1 192 ? 75.55900 0.43600   5.43200   1.000 42.58895  ? 188 SER H C    1 
ATOM   2780 O O    . SER A 1 192 ? 75.71700 -0.75600  5.71500   1.000 43.07815  ? 188 SER H O    1 
ATOM   2781 C CB   . SER A 1 192 ? 75.07300 1.27600   7.72900   1.000 40.54865  ? 188 SER H CB   1 
ATOM   2782 O OG   . SER A 1 192 ? 73.69000 1.23800   7.42200   1.000 42.90908  ? 188 SER H OG   1 
ATOM   2783 H H    . SER A 1 192 ? 74.99300 3.21500   6.21500   1.000 51.07449  ? 188 SER H H    1 
ATOM   2784 H HA   . SER A 1 192 ? 76.84800 1.37300   6.70500   1.000 50.91754  ? 188 SER H HA   1 
ATOM   2785 H HB2  . SER A 1 192 ? 75.32700 0.43200   8.13600   1.000 48.66195  ? 188 SER H HB2  1 
ATOM   2786 H HB3  . SER A 1 192 ? 75.23700 2.00500   8.34800   1.000 48.66195  ? 188 SER H HB3  1 
ATOM   2787 H HG   . SER A 1 192 ? 73.46800 1.93500   7.00900   1.000 51.49446  ? 188 SER H HG   1 
ATOM   2788 N N    . LEU A 1 193 ? 75.09500 0.83200   4.24200   1.000 42.58899  ? 189 LEU H N    1 
ATOM   2789 C CA   . LEU A 1 193 ? 74.71500 -0.15800  3.24000   1.000 42.88843  ? 189 LEU H CA   1 
ATOM   2790 C C    . LEU A 1 193 ? 75.91600 -0.96200  2.76000   1.000 42.95859  ? 189 LEU H C    1 
ATOM   2791 O O    . LEU A 1 193 ? 75.75400 -2.10200  2.30800   1.000 43.61877  ? 189 LEU H O    1 
ATOM   2792 C CB   . LEU A 1 193 ? 74.03900 0.51600   2.04800   1.000 40.15780  ? 189 LEU H CB   1 
ATOM   2793 C CG   . LEU A 1 193 ? 72.73600 1.26700   2.31800   1.000 38.84832  ? 189 LEU H CG   1 
ATOM   2794 C CD1  . LEU A 1 193 ? 72.06600 1.61900   1.00000   1.000 40.11817  ? 189 LEU H CD1  1 
ATOM   2795 C CD2  . LEU A 1 193 ? 71.79400 0.46500   3.19700   1.000 39.87878  ? 189 LEU H CD2  1 
ATOM   2796 H H    . LEU A 1 193 ? 74.99400 1.65100   3.99800   1.000 51.11036  ? 189 LEU H H    1 
ATOM   2797 H HA   . LEU A 1 193 ? 74.07700 -0.76600  3.64500   1.000 51.46968  ? 189 LEU H HA   1 
ATOM   2798 H HB2  . LEU A 1 193 ? 74.66300 1.15800   1.67600   1.000 48.19293  ? 189 LEU H HB2  1 
ATOM   2799 H HB3  . LEU A 1 193 ? 73.83900 -0.17000  1.39300   1.000 48.19293  ? 189 LEU H HB3  1 
ATOM   2800 H HG   . LEU A 1 193 ? 72.94100 2.08400   2.79800   1.000 46.62156  ? 189 LEU H HG   1 
ATOM   2801 H HD11 . LEU A 1 193 ? 71.23900 2.09200   1.18200   1.000 48.14537  ? 189 LEU H HD11 1 
ATOM   2802 H HD12 . LEU A 1 193 ? 72.66300 2.18300   0.48300   1.000 48.14537  ? 189 LEU H HD12 1 
ATOM   2803 H HD13 . LEU A 1 193 ? 71.87900 0.80200   0.51200   1.000 48.14537  ? 189 LEU H HD13 1 
ATOM   2804 H HD21 . LEU A 1 193 ? 70.93400 0.91200   3.22800   1.000 47.85811  ? 189 LEU H HD21 1 
ATOM   2805 H HD22 . LEU A 1 193 ? 71.69100 -0.42400  2.82200   1.000 47.85811  ? 189 LEU H HD22 1 
ATOM   2806 H HD23 . LEU A 1 193 ? 72.16900 0.40600   4.09000   1.000 47.85811  ? 189 LEU H HD23 1 
ATOM   2807 N N    . GLY A 1 194 ? 77.11300 -0.39700  2.83600   1.000 46.45970  ? 190 GLY H N    1 
ATOM   2808 C CA   . GLY A 1 194 ? 78.30300 -1.13400  2.47000   1.000 49.42880  ? 190 GLY H CA   1 
ATOM   2809 C C    . GLY A 1 194 ? 78.84800 -1.98400  3.60400   1.000 47.07852  ? 190 GLY H C    1 
ATOM   2810 O O    . GLY A 1 194 ? 79.44500 -3.03400  3.36200   1.000 46.09909  ? 190 GLY H O    1 
ATOM   2811 H H    . GLY A 1 194 ? 77.25800 0.41000   3.09700   1.000 55.75521  ? 190 GLY H H    1 
ATOM   2812 H HA2  . GLY A 1 194 ? 78.09800 -1.71900  1.72400   1.000 59.31813  ? 190 GLY H HA2  1 
ATOM   2813 H HA3  . GLY A 1 194 ? 78.99400 -0.50900  2.20100   1.000 59.31813  ? 190 GLY H HA3  1 
ATOM   2814 N N    . THR A 1 195 ? 78.63500 -1.53600  4.84400   1.000 46.24828  ? 191 THR H N    1 
ATOM   2815 C CA   . THR A 1 195 ? 79.13900 -2.22600  6.02800   1.000 47.22843  ? 191 THR H CA   1 
ATOM   2816 C C    . THR A 1 195 ? 78.19400 -3.32800  6.50100   1.000 47.64906  ? 191 THR H C    1 
ATOM   2817 O O    . THR A 1 195 ? 78.58600 -4.49500  6.60800   1.000 48.68957  ? 191 THR H O    1 
ATOM   2818 C CB   . THR A 1 195 ? 79.34600 -1.21900  7.17000   1.000 50.99847  ? 191 THR H CB   1 
ATOM   2819 O OG1  . THR A 1 195 ? 80.22300 -0.17300  6.73700   1.000 52.59909  ? 191 THR H OG1  1 
ATOM   2820 C CG2  . THR A 1 195 ? 79.92200 -1.90200  8.41500   1.000 52.43871  ? 191 THR H CG2  1 
ATOM   2821 H H    . THR A 1 195 ? 78.19400 -0.82000  5.02600   1.000 55.50150  ? 191 THR H H    1 
ATOM   2822 H HA   . THR A 1 195 ? 79.98900 -2.63000  5.79400   1.000 56.67769  ? 191 THR H HA   1 
ATOM   2823 H HB   . THR A 1 195 ? 78.48900 -0.83600  7.41700   1.000 61.20174  ? 191 THR H HB   1 
ATOM   2824 H HG1  . THR A 1 195 ? 80.22700 0.45100   7.30000   1.000 63.12248  ? 191 THR H HG1  1 
ATOM   2825 H HG21 . THR A 1 195 ? 80.01000 -1.25800  9.13600   1.000 62.93002  ? 191 THR H HG21 1 
ATOM   2826 H HG22 . THR A 1 195 ? 79.33500 -2.61800  8.70200   1.000 62.93002  ? 191 THR H HG22 1 
ATOM   2827 H HG23 . THR A 1 195 ? 80.79700 -2.27200  8.21600   1.000 62.93002  ? 191 THR H HG23 1 
ATOM   2828 N N    . GLN A 1 196 ? 76.95200 -2.96400  6.79800   1.000 45.01866  ? 192 GLN H N    1 
ATOM   2829 C CA   . GLN A 1 196 ? 76.05900 -3.81000  7.57300   1.000 42.58846  ? 192 GLN H CA   1 
ATOM   2830 C C    . GLN A 1 196 ? 75.25300 -4.73400  6.66900   1.000 39.15919  ? 192 GLN H C    1 
ATOM   2831 O O    . GLN A 1 196 ? 74.70700 -4.29800  5.65100   1.000 37.23922  ? 192 GLN H O    1 
ATOM   2832 C CB   . GLN A 1 196 ? 75.12200 -2.93700  8.41100   1.000 42.16836  ? 192 GLN H CB   1 
ATOM   2833 C CG   . GLN A 1 196 ? 74.21800 -3.71300  9.34800   1.000 42.30908  ? 192 GLN H CG   1 
ATOM   2834 C CD   . GLN A 1 196 ? 74.99400 -4.49300  10.38800  1.000 50.88870  ? 192 GLN H CD   1 
ATOM   2835 O OE1  . GLN A 1 196 ? 74.85100 -5.71100  10.49900  1.000 57.29733  ? 192 GLN H OE1  1 
ATOM   2836 N NE2  . GLN A 1 196 ? 75.82000 -3.79500  11.16000  1.000 56.96832  ? 192 GLN H NE2  1 
ATOM   2837 H H    . GLN A 1 196 ? 76.59800 -2.21900  6.55600   1.000 54.02597  ? 192 GLN H H    1 
ATOM   2838 H HA   . GLN A 1 196 ? 76.58400 -4.37500  8.16100   1.000 51.10972  ? 192 GLN H HA   1 
ATOM   2839 H HB2  . GLN A 1 196 ? 75.65900 -2.33600  8.95100   1.000 50.60560  ? 192 GLN H HB2  1 
ATOM   2840 H HB3  . GLN A 1 196 ? 74.55500 -2.42700  7.81100   1.000 50.60560  ? 192 GLN H HB3  1 
ATOM   2841 H HG2  . GLN A 1 196 ? 73.63400 -3.09300  9.81100   1.000 50.77447  ? 192 GLN H HG2  1 
ATOM   2842 H HG3  . GLN A 1 196 ? 73.69100 -4.34200  8.83100   1.000 50.77447  ? 192 GLN H HG3  1 
ATOM   2843 H HE21 . GLN A 1 196 ? 75.89100 -2.94400  11.05500  1.000 68.36555  ? 192 GLN H HE21 1 
ATOM   2844 H HE22 . GLN A 1 196 ? 76.28300 -4.19300  11.76600  1.000 68.36555  ? 192 GLN H HE22 1 
ATOM   2845 N N    . THR A 1 197 ? 75.18800 -6.01000  7.04600   1.000 37.31753  ? 193 THR H N    1 
ATOM   2846 C CA   . THR A 1 197 ? 74.28800 -6.95100  6.39500   1.000 33.98871  ? 193 THR H CA   1 
ATOM   2847 C C    . THR A 1 197 ? 72.89500 -6.83000  7.00100   1.000 29.11780  ? 193 THR H C    1 
ATOM   2848 O O    . THR A 1 197 ? 72.73800 -6.73300  8.22200   1.000 28.31691  ? 193 THR H O    1 
ATOM   2849 C CB   . THR A 1 197 ? 74.79700 -8.38400  6.54300   1.000 34.47833  ? 193 THR H CB   1 
ATOM   2850 O OG1  . THR A 1 197 ? 76.08100 -8.50800  5.91900   1.000 41.76865  ? 193 THR H OG1  1 
ATOM   2851 C CG2  . THR A 1 197 ? 73.83400 -9.36700  5.89300   1.000 33.59924  ? 193 THR H CG2  1 
ATOM   2852 H H    . THR A 1 197 ? 75.65800 -6.35400  7.67900   1.000 44.78461  ? 193 THR H H    1 
ATOM   2853 H HA   . THR A 1 197 ? 74.24100 -6.75200  5.44600   1.000 40.79002  ? 193 THR H HA   1 
ATOM   2854 H HB   . THR A 1 197 ? 74.87000 -8.60100  7.48600   1.000 41.37757  ? 193 THR H HB   1 
ATOM   2855 H HG1  . THR A 1 197 ? 76.38800 -9.27900  6.04400   1.000 50.12595  ? 193 THR H HG1  1 
ATOM   2856 H HG21 . THR A 1 197 ? 74.24400 -10.24500 5.83500   1.000 40.32266  ? 193 THR H HG21 1 
ATOM   2857 H HG22 . THR A 1 197 ? 73.02200 -9.43400  6.42000   1.000 40.32266  ? 193 THR H HG22 1 
ATOM   2858 H HG23 . THR A 1 197 ? 73.60600 -9.06700  4.99900   1.000 40.32266  ? 193 THR H HG23 1 
ATOM   2859 N N    . TYR A 1 198 ? 71.88400 -6.83000  6.13500   1.000 25.55630  ? 194 TYR H N    1 
ATOM   2860 C CA   . TYR A 1 198 ? 70.48900 -6.69200  6.53600   1.000 26.23888  ? 194 TYR H CA   1 
ATOM   2861 C C    . TYR A 1 198 ? 69.72000 -7.90700  6.04100   1.000 25.16955  ? 194 TYR H C    1 
ATOM   2862 O O    . TYR A 1 198 ? 69.63800 -8.14700  4.83100   1.000 22.31445  ? 194 TYR H O    1 
ATOM   2863 C CB   . TYR A 1 198 ? 69.89100 -5.39100  5.99300   1.000 27.07917  ? 194 TYR H CB   1 
ATOM   2864 C CG   . TYR A 1 198 ? 70.44900 -4.16200  6.68200   1.000 26.98767  ? 194 TYR H CG   1 
ATOM   2865 C CD1  . TYR A 1 198 ? 70.07500 -3.84600  7.98000   1.000 25.68747  ? 194 TYR H CD1  1 
ATOM   2866 C CD2  . TYR A 1 198 ? 71.35800 -3.32700  6.04400   1.000 30.62883  ? 194 TYR H CD2  1 
ATOM   2867 C CE1  . TYR A 1 198 ? 70.58600 -2.73300  8.62500   1.000 28.91855  ? 194 TYR H CE1  1 
ATOM   2868 C CE2  . TYR A 1 198 ? 71.87400 -2.20900  6.68300   1.000 30.94804  ? 194 TYR H CE2  1 
ATOM   2869 C CZ   . TYR A 1 198 ? 71.48200 -1.91800  7.97500   1.000 31.79931  ? 194 TYR H CZ   1 
ATOM   2870 O OH   . TYR A 1 198 ? 71.98100 -0.81100  8.62500   1.000 32.62904  ? 194 TYR H OH   1 
ATOM   2871 H H    . TYR A 1 198 ? 71.98600 -6.91000  5.28500   1.000 30.67113  ? 194 TYR H H    1 
ATOM   2872 H HA   . TYR A 1 198 ? 70.42200 -6.67100  7.50400   1.000 31.49023  ? 194 TYR H HA   1 
ATOM   2873 H HB2  . TYR A 1 198 ? 70.09100 -5.32300  5.04600   1.000 32.49858  ? 194 TYR H HB2  1 
ATOM   2874 H HB3  . TYR A 1 198 ? 68.93100 -5.40300  6.13000   1.000 32.49858  ? 194 TYR H HB3  1 
ATOM   2875 H HD1  . TYR A 1 198 ? 69.46900 -4.39300  8.42500   1.000 30.82854  ? 194 TYR H HD1  1 
ATOM   2876 H HD2  . TYR A 1 198 ? 71.62400 -3.52100  5.17400   1.000 36.75817  ? 194 TYR H HD2  1 
ATOM   2877 H HE1  . TYR A 1 198 ? 70.32300 -2.53700  9.49600   1.000 34.70583  ? 194 TYR H HE1  1 
ATOM   2878 H HE2  . TYR A 1 198 ? 72.48100 -1.65800  6.24300   1.000 37.14121  ? 194 TYR H HE2  1 
ATOM   2879 H HH   . TYR A 1 198 ? 72.54400 -0.42100  8.13800   1.000 39.15842  ? 194 TYR H HH   1 
ATOM   2880 N N    . ILE A 1 199 ? 69.17300 -8.67500  6.98000   1.000 22.06785  ? 195 ILE H N    1 
ATOM   2881 C CA   . ILE A 1 199 ? 68.44700 -9.90400  6.68800   1.000 23.15854  ? 195 ILE H CA   1 
ATOM   2882 C C    . ILE A 1 199 ? 67.09500 -9.82000  7.37600   1.000 20.16733  ? 195 ILE H C    1 
ATOM   2883 O O    . ILE A 1 199 ? 67.02100 -9.52200  8.57300   1.000 22.17927  ? 195 ILE H O    1 
ATOM   2884 C CB   . ILE A 1 199 ? 69.21300 -11.15200 7.16500   1.000 22.82861  ? 195 ILE H CB   1 
ATOM   2885 C CG1  . ILE A 1 199 ? 70.60400 -11.18800 6.53400   1.000 24.49899  ? 195 ILE H CG1  1 
ATOM   2886 C CG2  . ILE A 1 199 ? 68.44300 -12.42800 6.81600   1.000 22.88831  ? 195 ILE H CG2  1 
ATOM   2887 C CD1  . ILE A 1 199 ? 71.47800 -12.31700 7.03300   1.000 25.25928  ? 195 ILE H CD1  1 
ATOM   2888 H H    . ILE A 1 199 ? 69.21200 -8.49800  7.82100   1.000 26.48500  ? 195 ILE H H    1 
ATOM   2889 H HA   . ILE A 1 199 ? 68.30900 -9.97800  5.73100   1.000 27.79381  ? 195 ILE H HA   1 
ATOM   2890 H HB   . ILE A 1 199 ? 69.30300 -11.10200 8.13000   1.000 27.39790  ? 195 ILE H HB   1 
ATOM   2891 H HG12 . ILE A 1 199 ? 70.50800 -11.29100 5.57500   1.000 29.40236  ? 195 ILE H HG12 1 
ATOM   2892 H HG13 . ILE A 1 199 ? 71.05800 -10.35400 6.73400   1.000 29.40236  ? 195 ILE H HG13 1 
ATOM   2893 H HG21 . ILE A 1 199 ? 68.93800 -13.19500 7.14400   1.000 27.46955  ? 195 ILE H HG21 1 
ATOM   2894 H HG22 . ILE A 1 199 ? 67.56900 -12.39500 7.23500   1.000 27.46955  ? 195 ILE H HG22 1 
ATOM   2895 H HG23 . ILE A 1 199 ? 68.34600 -12.48500 5.85200   1.000 27.46955  ? 195 ILE H HG23 1 
ATOM   2896 H HD11 . ILE A 1 199 ? 72.37000 -12.21100 6.66800   1.000 30.31470  ? 195 ILE H HD11 1 
ATOM   2897 H HD12 . ILE A 1 199 ? 71.51100 -12.28600 8.00200   1.000 30.31470  ? 195 ILE H HD12 1 
ATOM   2898 H HD13 . ILE A 1 199 ? 71.09900 -13.16100 6.74300   1.000 30.31470  ? 195 ILE H HD13 1 
ATOM   2899 N N    . CYS A 1 200 ? 66.03300 -10.07900 6.63100   1.000 20.15583  ? 196 CYS H N    1 
ATOM   2900 C CA   . CYS A 1 200 ? 64.70000 -10.15800 7.20800   1.000 19.33770  ? 196 CYS H CA   1 
ATOM   2901 C C    . CYS A 1 200 ? 64.36300 -11.62300 7.44300   1.000 20.49886  ? 196 CYS H C    1 
ATOM   2902 O O    . CYS A 1 200 ? 64.57800 -12.46200 6.56300   1.000 19.48643  ? 196 CYS H O    1 
ATOM   2903 C CB   . CYS A 1 200 ? 63.67400 -9.47700  6.30700   1.000 20.14917  ? 196 CYS H CB   1 
ATOM   2904 S SG   . CYS A 1 200 ? 63.07400 -10.36100 4.86400   1.000 21.94842  ? 196 CYS H SG   1 
ATOM   2905 H H    . CYS A 1 200 ? 66.05800 -10.21400 5.78200   1.000 24.19056  ? 196 CYS H H    1 
ATOM   2906 H HA   . CYS A 1 200 ? 64.66900 -9.70000  8.06300   1.000 23.20881  ? 196 CYS H HA   1 
ATOM   2907 H HB2  . CYS A 1 200 ? 62.89500 -9.27600  6.85000   1.000 24.18257  ? 196 CYS H HB2  1 
ATOM   2908 H HB3  . CYS A 1 200 ? 64.07100 -8.65500  5.98000   1.000 24.18257  ? 196 CYS H HB3  1 
ATOM   2909 N N    . ASN A 1 201 ? 63.87700 -11.93200 8.64400   1.000 20.59903  ? 197 ASN H N    1 
ATOM   2910 C CA   . ASN A 1 201 ? 63.55300 -13.29600 9.04900   1.000 19.18813  ? 197 ASN H CA   1 
ATOM   2911 C C    . ASN A 1 201 ? 62.03900 -13.42500 9.06600   1.000 16.02573  ? 197 ASN H C    1 
ATOM   2912 O O    . ASN A 1 201 ? 61.37000 -12.84300 9.92700   1.000 17.29603  ? 197 ASN H O    1 
ATOM   2913 C CB   . ASN A 1 201 ? 64.14700 -13.62000 10.41200  1.000 21.59902  ? 197 ASN H CB   1 
ATOM   2914 C CG   . ASN A 1 201 ? 65.50700 -13.00800 10.60100  1.000 21.56766  ? 197 ASN H CG   1 
ATOM   2915 O OD1  . ASN A 1 201 ? 65.66900 -12.06200 11.37100  1.000 24.64988  ? 197 ASN H OD1  1 
ATOM   2916 N ND2  . ASN A 1 201 ? 66.49600 -13.52700 9.88500   1.000 24.05905  ? 197 ASN H ND2  1 
ATOM   2917 H H    . ASN A 1 201 ? 63.72200 -11.35000 9.25800   1.000 24.72241  ? 197 ASN H H    1 
ATOM   2918 H HA   . ASN A 1 201 ? 63.91800 -13.92400 8.40600   1.000 23.02933  ? 197 ASN H HA   1 
ATOM   2919 H HB2  . ASN A 1 201 ? 63.56200 -13.27500 11.10500  1.000 25.92240  ? 197 ASN H HB2  1 
ATOM   2920 H HB3  . ASN A 1 201 ? 64.23400 -14.58200 10.50100  1.000 25.92240  ? 197 ASN H HB3  1 
ATOM   2921 H HD21 . ASN A 1 201 ? 67.29200 -13.21000 9.95900   1.000 28.87443  ? 197 ASN H HD21 1 
ATOM   2922 H HD22 . ASN A 1 201 ? 66.34000 -14.18000 9.34800   1.000 28.87443  ? 197 ASN H HD22 1 
ATOM   2923 N N    . VAL A 1 202 ? 61.50800 -14.17900 8.11400   1.000 16.81757  ? 198 VAL H N    1 
ATOM   2924 C CA   . VAL A 1 202 ? 60.07300 -14.33300 7.93100   1.000 15.34607  ? 198 VAL H CA   1 
ATOM   2925 C C    . VAL A 1 202 ? 59.70700 -15.73500 8.37800   1.000 19.78935  ? 198 VAL H C    1 
ATOM   2926 O O    . VAL A 1 202 ? 60.25300 -16.71800 7.86400   1.000 18.72857  ? 198 VAL H O    1 
ATOM   2927 C CB   . VAL A 1 202 ? 59.66100 -14.10300 6.47000   1.000 15.76728  ? 198 VAL H CB   1 
ATOM   2928 C CG1  . VAL A 1 202 ? 58.14600 -14.14800 6.34000   1.000 16.81853  ? 198 VAL H CG1  1 
ATOM   2929 C CG2  . VAL A 1 202 ? 60.22200 -12.78500 5.95000   1.000 17.26859  ? 198 VAL H CG2  1 
ATOM   2930 H H    . VAL A 1 202 ? 61.97300 -14.62500 7.54500   1.000 20.18466  ? 198 VAL H H    1 
ATOM   2931 H HA   . VAL A 1 202 ? 59.60500 -13.69000 8.48700   1.000 18.41885  ? 198 VAL H HA   1 
ATOM   2932 H HB   . VAL A 1 202 ? 60.03000 -14.81200 5.92100   1.000 18.92431  ? 198 VAL H HB   1 
ATOM   2933 H HG11 . VAL A 1 202 ? 57.90100 -13.94300 5.42400   1.000 20.18581  ? 198 VAL H HG11 1 
ATOM   2934 H HG12 . VAL A 1 202 ? 57.83500 -15.03600 6.57600   1.000 20.18581  ? 198 VAL H HG12 1 
ATOM   2935 H HG13 . VAL A 1 202 ? 57.75800 -13.49200 6.94100   1.000 20.18581  ? 198 VAL H HG13 1 
ATOM   2936 H HG21 . VAL A 1 202 ? 59.90900 -12.64400 5.04200   1.000 20.72588  ? 198 VAL H HG21 1 
ATOM   2937 H HG22 . VAL A 1 202 ? 59.91500 -12.06300 6.52100   1.000 20.72588  ? 198 VAL H HG22 1 
ATOM   2938 H HG23 . VAL A 1 202 ? 61.19100 -12.82700 5.96200   1.000 20.72588  ? 198 VAL H HG23 1 
ATOM   2939 N N    . ASN A 1 203 ? 58.78100 -15.83100 9.32200   1.000 17.35639  ? 199 ASN H N    1 
ATOM   2940 C CA   . ASN A 1 203 ? 58.30900 -17.10900 9.83000   1.000 16.76564  ? 199 ASN H CA   1 
ATOM   2941 C C    . ASN A 1 203 ? 56.82400 -17.22700 9.52400   1.000 18.45808  ? 199 ASN H C    1 
ATOM   2942 O O    . ASN A 1 203 ? 56.04300 -16.32900 9.85700   1.000 18.76833  ? 199 ASN H O    1 
ATOM   2943 C CB   . ASN A 1 203 ? 58.57200 -17.23300 11.33400  1.000 20.49769  ? 199 ASN H CB   1 
ATOM   2944 C CG   . ASN A 1 203 ? 58.45900 -18.66400 11.82700  1.000 24.63856  ? 199 ASN H CG   1 
ATOM   2945 O OD1  . ASN A 1 203 ? 58.41700 -19.60100 11.03400  1.000 24.03962  ? 199 ASN H OD1  1 
ATOM   2946 N ND2  . ASN A 1 203 ? 58.41300 -18.83800 13.14200  1.000 30.78917  ? 199 ASN H ND2  1 
ATOM   2947 H H    . ASN A 1 203 ? 58.40300 -15.15300 9.69200   1.000 20.83124  ? 199 ASN H H    1 
ATOM   2948 H HA   . ASN A 1 203 ? 58.77100 -17.84000 9.39200   1.000 20.12234  ? 199 ASN H HA   1 
ATOM   2949 H HB2  . ASN A 1 203 ? 59.46900 -16.91800 11.52600  1.000 24.60080  ? 199 ASN H HB2  1 
ATOM   2950 H HB3  . ASN A 1 203 ? 57.92200 -16.69700 11.81500  1.000 24.60080  ? 199 ASN H HB3  1 
ATOM   2951 H HD21 . ASN A 1 203 ? 58.35000 -19.63100 13.46900  1.000 36.95058  ? 199 ASN H HD21 1 
ATOM   2952 H HD22 . ASN A 1 203 ? 58.44700 -18.15800 13.66800  1.000 36.95058  ? 199 ASN H HD22 1 
ATOM   2953 N N    . HIS A 1 204 ? 56.44400 -18.31500 8.86300   1.000 14.94579  ? 200 HIS H N    1 
ATOM   2954 C CA   . HIS A 1 204 ? 55.04300 -18.63000 8.58800   1.000 14.85596  ? 200 HIS H CA   1 
ATOM   2955 C C    . HIS A 1 204 ? 54.76700 -19.99100 9.22000   1.000 18.96903  ? 200 HIS H C    1 
ATOM   2956 O O    . HIS A 1 204 ? 54.82300 -21.02300 8.55100   1.000 19.04836  ? 200 HIS H O    1 
ATOM   2957 C CB   . HIS A 1 204 ? 54.76000 -18.62300 7.08600   1.000 17.55793  ? 200 HIS H CB   1 
ATOM   2958 C CG   . HIS A 1 204 ? 53.31200 -18.78100 6.74200   1.000 14.91611  ? 200 HIS H CG   1 
ATOM   2959 N ND1  . HIS A 1 204 ? 52.84800 -19.79100 5.92800   1.000 16.59767  ? 200 HIS H ND1  1 
ATOM   2960 C CD2  . HIS A 1 204 ? 52.22500 -18.05500 7.09700   1.000 15.79739  ? 200 HIS H CD2  1 
ATOM   2961 C CE1  . HIS A 1 204 ? 51.53800 -19.68400 5.79900   1.000 14.74683  ? 200 HIS H CE1  1 
ATOM   2962 N NE2  . HIS A 1 204 ? 51.13400 -18.64000 6.50000   1.000 14.07759  ? 200 HIS H NE2  1 
ATOM   2963 H H    . HIS A 1 204 ? 56.99200 -18.90200 8.55600   1.000 17.93852  ? 200 HIS H H    1 
ATOM   2964 H HA   . HIS A 1 204 ? 54.46800 -17.96400 8.99500   1.000 17.83072  ? 200 HIS H HA   1 
ATOM   2965 H HB2  . HIS A 1 204 ? 55.06200 -17.77900 6.71600   1.000 21.07309  ? 200 HIS H HB2  1 
ATOM   2966 H HB3  . HIS A 1 204 ? 55.24300 -19.35700 6.67500   1.000 21.07309  ? 200 HIS H HB3  1 
ATOM   2967 H HD2  . HIS A 1 204 ? 52.21800 -17.30200 7.64200   1.000 18.96043  ? 200 HIS H HD2  1 
ATOM   2968 H HE1  . HIS A 1 204 ? 50.99200 -20.24700 5.29900   1.000 17.69977  ? 200 HIS H HE1  1 
ATOM   2969 H HE2  . HIS A 1 204 ? 50.32100 -18.37000 6.57200   1.000 16.89668  ? 200 HIS H HE2  1 
ATOM   2970 N N    . LYS A 1 205 ? 54.47600 -19.98800 10.52000  1.000 17.87685  ? 201 LYS H N    1 
ATOM   2971 C CA   . LYS A 1 205 ? 54.27900 -21.25300 11.22000  1.000 20.00807  ? 201 LYS H CA   1 
ATOM   2972 C C    . LYS A 1 205 ? 53.14500 -22.08300 10.63600  1.000 19.78838  ? 201 LYS H C    1 
ATOM   2973 O O    . LYS A 1 205 ? 53.27300 -23.32100 10.62200  1.000 15.66584  ? 201 LYS H O    1 
ATOM   2974 C CB   . LYS A 1 205 ? 54.04600 -20.99100 12.71300  1.000 21.50748  ? 201 LYS H CB   1 
ATOM   2975 C CG   . LYS A 1 205 ? 55.27100 -20.43700 13.42000  1.000 30.86916  ? 201 LYS H CG   1 
ATOM   2976 C CD   . LYS A 1 205 ? 55.07300 -20.35400 14.92500  1.000 40.15824  ? 201 LYS H CD   1 
ATOM   2977 C CE   . LYS A 1 205 ? 56.32900 -19.84100 15.61500  1.000 46.06828  ? 201 LYS H CE   1 
ATOM   2978 N NZ   . LYS A 1 205 ? 56.08300 -19.48700 17.04200  1.000 48.98873  ? 201 LYS H NZ   1 
ATOM   2979 H H    . LYS A 1 205 ? 54.38800 -19.28500 11.00800  1.000 21.45579  ? 201 LYS H H    1 
ATOM   2980 H HA   . LYS A 1 205 ? 55.09600 -21.76800 11.13000  1.000 24.01325  ? 201 LYS H HA   1 
ATOM   2981 H HB2  . LYS A 1 205 ? 53.32700 -20.34700 12.81100  1.000 25.81255  ? 201 LYS H HB2  1 
ATOM   2982 H HB3  . LYS A 1 205 ? 53.80500 -21.82600 13.14500  1.000 25.81255  ? 201 LYS H HB3  1 
ATOM   2983 H HG2  . LYS A 1 205 ? 56.03000 -21.01600 13.24600  1.000 37.04656  ? 201 LYS H HG2  1 
ATOM   2984 H HG3  . LYS A 1 205 ? 55.45300 -19.54300 13.08900  1.000 37.04656  ? 201 LYS H HG3  1 
ATOM   2985 H HD2  . LYS A 1 205 ? 54.34500 -19.74400 15.12200  1.000 48.19346  ? 201 LYS H HD2  1 
ATOM   2986 H HD3  . LYS A 1 205 ? 54.87100 -21.23600 15.27300  1.000 48.19346  ? 201 LYS H HD3  1 
ATOM   2987 H HE2  . LYS A 1 205 ? 57.01200 -20.53000 15.58800  1.000 55.28551  ? 201 LYS H HE2  1 
ATOM   2988 H HE3  . LYS A 1 205 ? 56.64300 -19.04600 15.15600  1.000 55.28551  ? 201 LYS H HE3  1 
ATOM   2989 H HZ1  . LYS A 1 205 ? 56.83400 -19.18800 17.41600  1.000 58.79005  ? 201 LYS H HZ1  1 
ATOM   2990 H HZ2  . LYS A 1 205 ? 55.46200 -18.85200 17.09600  1.000 58.79005  ? 201 LYS H HZ2  1 
ATOM   2991 H HZ3  . LYS A 1 205 ? 55.80300 -20.20300 17.49000  1.000 58.79005  ? 201 LYS H HZ3  1 
ATOM   2992 N N    . PRO A 1 206 ? 52.04300 -21.50900 10.15100  1.000 18.36646  ? 202 PRO H N    1 
ATOM   2993 C CA   . PRO A 1 206 ? 50.97900 -22.35400 9.58500   1.000 19.42809  ? 202 PRO H CA   1 
ATOM   2994 C C    . PRO A 1 206 ? 51.45800 -23.31000 8.50000   1.000 19.30802  ? 202 PRO H C    1 
ATOM   2995 O O    . PRO A 1 206 ? 50.85800 -24.37800 8.32700   1.000 20.59862  ? 202 PRO H O    1 
ATOM   2996 C CB   . PRO A 1 206 ? 49.97700 -21.32600 9.04000   1.000 18.35792  ? 202 PRO H CB   1 
ATOM   2997 C CG   . PRO A 1 206 ? 50.16200 -20.12800 9.90900   1.000 19.58888  ? 202 PRO H CG   1 
ATOM   2998 C CD   . PRO A 1 206 ? 51.63500 -20.09300 10.24500  1.000 20.95006  ? 202 PRO H CD   1 
ATOM   2999 H HA   . PRO A 1 206 ? 50.55800 -22.86900 10.29200  1.000 23.31727  ? 202 PRO H HA   1 
ATOM   3000 H HB2  . PRO A 1 206 ? 50.18200 -21.12000 8.11500   1.000 22.03308  ? 202 PRO H HB2  1 
ATOM   3001 H HB3  . PRO A 1 206 ? 49.07400 -21.67200 9.11100   1.000 22.03308  ? 202 PRO H HB3  1 
ATOM   3002 H HG2  . PRO A 1 206 ? 49.89900 -19.32800 9.42600   1.000 23.51023  ? 202 PRO H HG2  1 
ATOM   3003 H HG3  . PRO A 1 206 ? 49.62700 -20.22000 10.71300  1.000 23.51023  ? 202 PRO H HG3  1 
ATOM   3004 H HD2  . PRO A 1 206 ? 52.12100 -19.55000 9.60500   1.000 25.14364  ? 202 PRO H HD2  1 
ATOM   3005 H HD3  . PRO A 1 206 ? 51.77500 -19.75300 11.14300  1.000 25.14364  ? 202 PRO H HD3  1 
ATOM   3006 N N    . SER A 1 207 ? 52.51600 -22.96500 7.76200   1.000 17.67693  ? 203 SER H N    1 
ATOM   3007 C CA   . SER A 1 207 ? 53.06600 -23.83200 6.72600   1.000 20.20882  ? 203 SER H CA   1 
ATOM   3008 C C    . SER A 1 207 ? 54.41200 -24.42900 7.12600   1.000 21.66895  ? 203 SER H C    1 
ATOM   3009 O O    . SER A 1 207 ? 55.06700 -25.07300 6.30000   1.000 21.31743  ? 203 SER H O    1 
ATOM   3010 C CB   . SER A 1 207 ? 53.20000 -23.06500 5.40300   1.000 21.93001  ? 203 SER H CB   1 
ATOM   3011 O OG   . SER A 1 207 ? 54.27900 -22.14300 5.41300   1.000 17.83560  ? 203 SER H OG   1 
ATOM   3012 H H    . SER A 1 207 ? 52.93700 -22.22000 7.84700   1.000 21.21588  ? 203 SER H H    1 
ATOM   3013 H HA   . SER A 1 207 ? 52.44900 -24.56500 6.57800   1.000 24.25415  ? 203 SER H HA   1 
ATOM   3014 H HB2  . SER A 1 207 ? 53.34700 -23.70500 4.68900   1.000 26.31958  ? 203 SER H HB2  1 
ATOM   3015 H HB3  . SER A 1 207 ? 52.37800 -22.57600 5.24600   1.000 26.31958  ? 203 SER H HB3  1 
ATOM   3016 H HG   . SER A 1 207 ? 54.27200 -21.70000 6.12600   1.000 21.40629  ? 203 SER H HG   1 
ATOM   3017 N N    . ASN A 1 208 ? 54.83100 -24.23900 8.37600   1.000 17.59599  ? 204 ASN H N    1 
ATOM   3018 C CA   . ASN A 1 208 ? 56.13900 -24.68400 8.85700   1.000 19.65789  ? 204 ASN H CA   1 
ATOM   3019 C C    . ASN A 1 208 ? 57.26200 -24.24100 7.91900   1.000 20.19735  ? 204 ASN H C    1 
ATOM   3020 O O    . ASN A 1 208 ? 58.16200 -25.01300 7.57900   1.000 17.00581  ? 204 ASN H O    1 
ATOM   3021 C CB   . ASN A 1 208 ? 56.15400 -26.20100 9.04900   1.000 23.01940  ? 204 ASN H CB   1 
ATOM   3022 C CG   . ASN A 1 208 ? 55.09200 -26.66800 10.01400  1.000 23.19816  ? 204 ASN H CG   1 
ATOM   3023 O OD1  . ASN A 1 208 ? 55.16400 -26.39200 11.20800  1.000 23.92880  ? 204 ASN H OD1  1 
ATOM   3024 N ND2  . ASN A 1 208 ? 54.09200 -27.37200 9.50000   1.000 30.46078  ? 204 ASN H ND2  1 
ATOM   3025 H H    . ASN A 1 208 ? 54.36400 -23.84300 8.98000   1.000 21.11876  ? 204 ASN H H    1 
ATOM   3026 H HA   . ASN A 1 208 ? 56.30200 -24.26500 9.71600   1.000 23.59304  ? 204 ASN H HA   1 
ATOM   3027 H HB2  . ASN A 1 208 ? 55.99600 -26.63100 8.19400   1.000 27.62685  ? 204 ASN H HB2  1 
ATOM   3028 H HB3  . ASN A 1 208 ? 57.01900 -26.46700 9.40000   1.000 27.62685  ? 204 ASN H HB3  1 
ATOM   3029 H HD21 . ASN A 1 208 ? 53.46300 -27.66100 10.01000  1.000 36.55650  ? 204 ASN H HD21 1 
ATOM   3030 H HD22 . ASN A 1 208 ? 54.07300 -27.54000 8.65700   1.000 36.55650  ? 204 ASN H HD22 1 
ATOM   3031 N N    . THR A 1 209 ? 57.21200 -22.96900 7.51600   1.000 15.63531  ? 205 THR H N    1 
ATOM   3032 C CA   . THR A 1 209 ? 58.18000 -22.37800 6.59800   1.000 17.85686  ? 205 THR H CA   1 
ATOM   3033 C C    . THR A 1 209 ? 58.80800 -21.14700 7.23700   1.000 19.49793  ? 205 THR H C    1 
ATOM   3034 O O    . THR A 1 209 ? 58.09800 -20.31000 7.80100   1.000 18.77904  ? 205 THR H O    1 
ATOM   3035 C CB   . THR A 1 209 ? 57.51800 -21.97700 5.27200   1.000 19.30724  ? 205 THR H CB   1 
ATOM   3036 O OG1  . THR A 1 209 ? 56.87700 -23.11400 4.68500   1.000 23.08913  ? 205 THR H OG1  1 
ATOM   3037 C CG2  . THR A 1 209 ? 58.54800 -21.42200 4.29300   1.000 22.96951  ? 205 THR H CG2  1 
ATOM   3038 H H    . THR A 1 209 ? 56.60600 -22.41500 7.77000   1.000 18.76595  ? 205 THR H H    1 
ATOM   3039 H HA   . THR A 1 209 ? 58.87700 -23.02900 6.42000   1.000 21.43181  ? 205 THR H HA   1 
ATOM   3040 H HB   . THR A 1 209 ? 56.85900 -21.28600 5.44600   1.000 23.17226  ? 205 THR H HB   1 
ATOM   3041 H HG1  . THR A 1 209 ? 56.06000 -23.11800 4.88200   1.000 27.71053  ? 205 THR H HG1  1 
ATOM   3042 H HG21 . THR A 1 209 ? 58.12100 -21.21100 3.44700   1.000 27.56698  ? 205 THR H HG21 1 
ATOM   3043 H HG22 . THR A 1 209 ? 58.94900 -20.61600 4.65400   1.000 27.56698  ? 205 THR H HG22 1 
ATOM   3044 H HG23 . THR A 1 209 ? 59.24500 -22.07900 4.13800   1.000 27.56698  ? 205 THR H HG23 1 
ATOM   3045 N N    . LYS A 1 210 ? 60.13400 -21.04600 7.15100   1.000 17.91616  ? 206 LYS H N    1 
ATOM   3046 C CA   . LYS A 1 210 ? 60.87400 -19.85200 7.53500   1.000 18.74730  ? 206 LYS H CA   1 
ATOM   3047 C C    . LYS A 1 210 ? 61.73000 -19.41600 6.35800   1.000 19.61887  ? 206 LYS H C    1 
ATOM   3048 O O    . LYS A 1 210 ? 62.36300 -20.24900 5.70300   1.000 19.26786  ? 206 LYS H O    1 
ATOM   3049 C CB   . LYS A 1 210 ? 61.78500 -20.09000 8.73700   1.000 21.59762  ? 206 LYS H CB   1 
ATOM   3050 C CG   . LYS A 1 210 ? 61.07100 -20.22500 10.06100  1.000 27.42887  ? 206 LYS H CG   1 
ATOM   3051 C CD   . LYS A 1 210 ? 62.03200 -20.69600 11.15100  1.000 33.10869  ? 206 LYS H CD   1 
ATOM   3052 C CE   . LYS A 1 210 ? 61.29700 -21.02700 12.44400  1.000 33.94770  ? 206 LYS H CE   1 
ATOM   3053 N NZ   . LYS A 1 210 ? 62.05700 -22.00300 13.27800  1.000 47.00879  ? 206 LYS H NZ   1 
ATOM   3054 H H    . LYS A 1 210 ? 60.64100 -21.67800 6.86400   1.000 21.50297  ? 206 LYS H H    1 
ATOM   3055 H HA   . LYS A 1 210 ? 60.24400 -19.15300 7.76900   1.000 22.50033  ? 206 LYS H HA   1 
ATOM   3056 H HB2  . LYS A 1 210 ? 62.28000 -20.91100 8.58900   1.000 25.92072  ? 206 LYS H HB2  1 
ATOM   3057 H HB3  . LYS A 1 210 ? 62.39700 -19.34200 8.81200   1.000 25.92072  ? 206 LYS H HB3  1 
ATOM   3058 H HG2  . LYS A 1 210 ? 60.70700 -19.36500 10.32200  1.000 32.91821  ? 206 LYS H HG2  1 
ATOM   3059 H HG3  . LYS A 1 210 ? 60.35600 -20.87600 9.97900   1.000 32.91821  ? 206 LYS H HG3  1 
ATOM   3060 H HD2  . LYS A 1 210 ? 62.49200 -21.49500 10.85000  1.000 39.73400  ? 206 LYS H HD2  1 
ATOM   3061 H HD3  . LYS A 1 210 ? 62.67400 -19.99400 11.33800  1.000 39.73400  ? 206 LYS H HD3  1 
ATOM   3062 H HE2  . LYS A 1 210 ? 61.17700 -20.21500 12.96100  1.000 40.74081  ? 206 LYS H HE2  1 
ATOM   3063 H HE3  . LYS A 1 210 ? 60.43400 -21.41600 12.23200  1.000 40.74081  ? 206 LYS H HE3  1 
ATOM   3064 H HZ1  . LYS A 1 210 ? 61.60000 -22.19200 14.01800  1.000 56.41412  ? 206 LYS H HZ1  1 
ATOM   3065 H HZ2  . LYS A 1 210 ? 62.19000 -22.75500 12.82100  1.000 56.41412  ? 206 LYS H HZ2  1 
ATOM   3066 H HZ3  . LYS A 1 210 ? 62.84600 -21.66000 13.50500  1.000 56.41412  ? 206 LYS H HZ3  1 
ATOM   3067 N N    . VAL A 1 211 ? 61.76700 -18.11500 6.10100   1.000 17.98883  ? 207 VAL H N    1 
ATOM   3068 C CA   . VAL A 1 211 ? 62.56600 -17.55500 5.02000   1.000 16.12528  ? 207 VAL H CA   1 
ATOM   3069 C C    . VAL A 1 211 ? 63.46300 -16.47500 5.60500   1.000 18.74704  ? 207 VAL H C    1 
ATOM   3070 O O    . VAL A 1 211 ? 62.98200 -15.58000 6.30800   1.000 19.10872  ? 207 VAL H O    1 
ATOM   3071 C CB   . VAL A 1 211 ? 61.67600 -16.98600 3.90000   1.000 17.86742  ? 207 VAL H CB   1 
ATOM   3072 C CG1  . VAL A 1 211 ? 62.52300 -16.46400 2.75700   1.000 20.25867  ? 207 VAL H CG1  1 
ATOM   3073 C CG2  . VAL A 1 211 ? 60.70300 -18.05500 3.40500   1.000 20.70997  ? 207 VAL H CG2  1 
ATOM   3074 H H    . VAL A 1 211 ? 61.32800 -17.52500 6.54700   1.000 21.59016  ? 207 VAL H H    1 
ATOM   3075 H HA   . VAL A 1 211 ? 63.13400 -18.24200 4.63800   1.000 19.35391  ? 207 VAL H HA   1 
ATOM   3076 H HB   . VAL A 1 211 ? 61.16100 -16.24300 4.25200   1.000 21.44447  ? 207 VAL H HB   1 
ATOM   3077 H HG11 . VAL A 1 211 ? 61.94000 -16.15100 2.04800   1.000 24.31397  ? 207 VAL H HG11 1 
ATOM   3078 H HG12 . VAL A 1 211 ? 63.07300 -15.73200 3.07900   1.000 24.31397  ? 207 VAL H HG12 1 
ATOM   3079 H HG13 . VAL A 1 211 ? 63.08800 -17.18100 2.42900   1.000 24.31397  ? 207 VAL H HG13 1 
ATOM   3080 H HG21 . VAL A 1 211 ? 60.19300 -17.69800 2.66100   1.000 24.85553  ? 207 VAL H HG21 1 
ATOM   3081 H HG22 . VAL A 1 211 ? 61.20800 -18.83200 3.11700   1.000 24.85553  ? 207 VAL H HG22 1 
ATOM   3082 H HG23 . VAL A 1 211 ? 60.10600 -18.29900 4.13000   1.000 24.85553  ? 207 VAL H HG23 1 
ATOM   3083 N N    . ASP A 1 212 ? 64.76200 -16.57200 5.33900   1.000 19.88679  ? 208 ASP H N    1 
ATOM   3084 C CA   . ASP A 1 212 ? 65.71700 -15.51300 5.64500   1.000 22.42876  ? 208 ASP H CA   1 
ATOM   3085 C C    . ASP A 1 212 ? 66.20000 -14.93100 4.32300   1.000 24.67088  ? 208 ASP H C    1 
ATOM   3086 O O    . ASP A 1 212 ? 66.73800 -15.65800 3.48000   1.000 24.33793  ? 208 ASP H O    1 
ATOM   3087 C CB   . ASP A 1 212 ? 66.88800 -16.03900 6.47000   1.000 20.79673  ? 208 ASP H CB   1 
ATOM   3088 C CG   . ASP A 1 212 ? 66.43900 -16.71800 7.74500   1.000 25.44892  ? 208 ASP H CG   1 
ATOM   3089 O OD1  . ASP A 1 212 ? 65.77300 -16.06200 8.57200   1.000 23.39864  ? 208 ASP H OD1  1 
ATOM   3090 O OD2  . ASP A 1 212 ? 66.73700 -17.91800 7.91300   1.000 33.52051  ? 208 ASP H OD2  1 
ATOM   3091 H H    . ASP A 1 212 ? 65.12300 -17.26100 4.97200   1.000 23.86771  ? 208 ASP H H    1 
ATOM   3092 H HA   . ASP A 1 212 ? 65.28600 -14.81600 6.16300   1.000 26.91808  ? 208 ASP H HA   1 
ATOM   3093 H HB2  . ASP A 1 212 ? 67.38300 -16.68500 5.94300   1.000 24.95964  ? 208 ASP H HB2  1 
ATOM   3094 H HB3  . ASP A 1 212 ? 67.46400 -15.29600 6.71100   1.000 24.95964  ? 208 ASP H HB3  1 
ATOM   3095 N N    . LYS A 1 213 ? 65.99000 -13.63200 4.13700   1.000 20.58636  ? 209 LYS H N    1 
ATOM   3096 C CA   . LYS A 1 213 ? 66.31200 -12.94900 2.89200   1.000 22.24738  ? 209 LYS H CA   1 
ATOM   3097 C C    . LYS A 1 213 ? 67.33100 -11.86100 3.18800   1.000 23.69822  ? 209 LYS H C    1 
ATOM   3098 O O    . LYS A 1 213 ? 67.05400 -10.94600 3.96900   1.000 23.10915  ? 209 LYS H O    1 
ATOM   3099 C CB   . LYS A 1 213 ? 65.05400 -12.34800 2.26100   1.000 24.17892  ? 209 LYS H CB   1 
ATOM   3100 C CG   . LYS A 1 213 ? 65.29000 -11.65800 0.92900   1.000 21.60669  ? 209 LYS H CG   1 
ATOM   3101 C CD   . LYS A 1 213 ? 65.30700 -12.65300 -0.19900  1.000 25.67845  ? 209 LYS H CD   1 
ATOM   3102 C CE   . LYS A 1 213 ? 66.01100 -12.08800 -1.40700  1.000 31.25969  ? 209 LYS H CE   1 
ATOM   3103 N NZ   . LYS A 1 213 ? 65.84800 -12.98200 -2.57700  1.000 37.49947  ? 209 LYS H NZ   1 
ATOM   3104 H H    . LYS A 1 213 ? 65.65400 -13.11300 4.73400   1.000 24.70721  ? 209 LYS H H    1 
ATOM   3105 H HA   . LYS A 1 213 ? 66.70300 -13.57700 2.26400   1.000 26.70042  ? 209 LYS H HA   1 
ATOM   3106 H HB2  . LYS A 1 213 ? 64.41200 -13.06000 2.11300   1.000 29.01828  ? 209 LYS H HB2  1 
ATOM   3107 H HB3  . LYS A 1 213 ? 64.68500 -11.69100 2.87100   1.000 29.01828  ? 209 LYS H HB3  1 
ATOM   3108 H HG2  . LYS A 1 213 ? 64.57800 -11.02000 0.76600   1.000 25.93159  ? 209 LYS H HG2  1 
ATOM   3109 H HG3  . LYS A 1 213 ? 66.14600 -11.20100 0.94900   1.000 25.93159  ? 209 LYS H HG3  1 
ATOM   3110 H HD2  . LYS A 1 213 ? 65.77600 -13.45400 0.08300   1.000 30.81771  ? 209 LYS H HD2  1 
ATOM   3111 H HD3  . LYS A 1 213 ? 64.39600 -12.87300 -0.45000  1.000 30.81771  ? 209 LYS H HD3  1 
ATOM   3112 H HE2  . LYS A 1 213 ? 65.63300 -11.22200 -1.62700  1.000 37.51519  ? 209 LYS H HE2  1 
ATOM   3113 H HE3  . LYS A 1 213 ? 66.95800 -11.99900 -1.21800  1.000 37.51519  ? 209 LYS H HE3  1 
ATOM   3114 H HZ1  . LYS A 1 213 ? 65.08200 -12.80200 -2.99300  1.000 45.00293  ? 209 LYS H HZ1  1 
ATOM   3115 H HZ2  . LYS A 1 213 ? 66.52100 -12.86200 -3.14700  1.000 45.00293  ? 209 LYS H HZ2  1 
ATOM   3116 H HZ3  . LYS A 1 213 ? 65.84100 -13.83100 -2.31300  1.000 45.00293  ? 209 LYS H HZ3  1 
ATOM   3117 N N    . LYS A 1 214 ? 68.50800 -11.97100 2.58100   1.000 23.75641  ? 210 LYS H N    1 
ATOM   3118 C CA   . LYS A 1 214 ? 69.51200 -10.91700 2.65700   1.000 25.58900  ? 210 LYS H CA   1 
ATOM   3119 C C    . LYS A 1 214 ? 69.13900 -9.83600  1.65000   1.000 24.96747  ? 210 LYS H C    1 
ATOM   3120 O O    . LYS A 1 214 ? 68.97600 -10.12300 0.46000   1.000 25.57737  ? 210 LYS H O    1 
ATOM   3121 C CB   . LYS A 1 214 ? 70.89700 -11.49200 2.37400   1.000 28.51843  ? 210 LYS H CB   1 
ATOM   3122 C CG   . LYS A 1 214 ? 72.05800 -10.52100 2.53700   1.000 29.54720  ? 210 LYS H CG   1 
ATOM   3123 C CD   . LYS A 1 214 ? 73.35800 -11.16600 2.05600   1.000 44.13846  ? 210 LYS H CD   1 
ATOM   3124 C CE   . LYS A 1 214 ? 74.59100 -10.35100 2.42900   1.000 52.39806  ? 210 LYS H CE   1 
ATOM   3125 N NZ   . LYS A 1 214 ? 74.63400 -9.01600  1.76600   1.000 53.38852  ? 210 LYS H NZ   1 
ATOM   3126 H H    . LYS A 1 214 ? 68.75100 -12.65200 2.11600   1.000 28.51126  ? 210 LYS H H    1 
ATOM   3127 H HA   . LYS A 1 214 ? 69.53600 -10.52500 3.54400   1.000 30.71037  ? 210 LYS H HA   1 
ATOM   3128 H HB2  . LYS A 1 214 ? 71.05100 -12.23000 2.98300   1.000 34.22569  ? 210 LYS H HB2  1 
ATOM   3129 H HB3  . LYS A 1 214 ? 70.91300 -11.81000 1.45700   1.000 34.22569  ? 210 LYS H HB3  1 
ATOM   3130 H HG2  . LYS A 1 214 ? 71.89300 -9.72400  2.00800   1.000 35.46021  ? 210 LYS H HG2  1 
ATOM   3131 H HG3  . LYS A 1 214 ? 72.15600 -10.28400 3.47200   1.000 35.46021  ? 210 LYS H HG3  1 
ATOM   3132 H HD2  . LYS A 1 214 ? 73.44400 -12.04300 2.46000   1.000 52.96972  ? 210 LYS H HD2  1 
ATOM   3133 H HD3  . LYS A 1 214 ? 73.33300 -11.24700 1.09000   1.000 52.96972  ? 210 LYS H HD3  1 
ATOM   3134 H HE2  . LYS A 1 214 ? 74.59600 -10.20700 3.38800   1.000 62.88125  ? 210 LYS H HE2  1 
ATOM   3135 H HE3  . LYS A 1 214 ? 75.38500 -10.84100 2.16300   1.000 62.88125  ? 210 LYS H HE3  1 
ATOM   3136 H HZ1  . LYS A 1 214 ? 73.88400 -8.56800  1.93600   1.000 64.06979  ? 210 LYS H HZ1  1 
ATOM   3137 H HZ2  . LYS A 1 214 ? 75.32600 -8.54700  2.07100   1.000 64.06979  ? 210 LYS H HZ2  1 
ATOM   3138 H HZ3  . LYS A 1 214 ? 74.71700 -9.11600  0.88600   1.000 64.06979  ? 210 LYS H HZ3  1 
ATOM   3139 N N    . VAL A 1 215 ? 68.97200 -8.60600  2.12300   1.000 25.94844  ? 211 VAL H N    1 
ATOM   3140 C CA   . VAL A 1 215 ? 68.54800 -7.49100  1.28300   1.000 26.42787  ? 211 VAL H CA   1 
ATOM   3141 C C    . VAL A 1 215 ? 69.78300 -6.66100  0.95100   1.000 28.70800  ? 211 VAL H C    1 
ATOM   3142 O O    . VAL A 1 215 ? 70.34000 -5.98100  1.82000   1.000 29.09811  ? 211 VAL H O    1 
ATOM   3143 C CB   . VAL A 1 215 ? 67.47300 -6.63800  1.97200   1.000 23.58764  ? 211 VAL H CB   1 
ATOM   3144 C CG1  . VAL A 1 215 ? 67.02000 -5.51100  1.05700   1.000 25.88853  ? 211 VAL H CG1  1 
ATOM   3145 C CG2  . VAL A 1 215 ? 66.28400 -7.49300  2.38000   1.000 21.91818  ? 211 VAL H CG2  1 
ATOM   3146 H H    . VAL A 1 215 ? 69.10200 -8.38700  2.94500   1.000 31.14170  ? 211 VAL H H    1 
ATOM   3147 H HA   . VAL A 1 215 ? 68.18000 -7.83900  0.45600   1.000 31.71701  ? 211 VAL H HA   1 
ATOM   3148 H HB   . VAL A 1 215 ? 67.85700 -6.25000  2.77400   1.000 28.30874  ? 211 VAL H HB   1 
ATOM   3149 H HG11 . VAL A 1 215 ? 66.28700 -5.03700  1.48000   1.000 31.06981  ? 211 VAL H HG11 1 
ATOM   3150 H HG12 . VAL A 1 215 ? 67.76400 -4.90600  0.91000   1.000 31.06981  ? 211 VAL H HG12 1 
ATOM   3151 H HG13 . VAL A 1 215 ? 66.72800 -5.88800  0.21300   1.000 31.06981  ? 211 VAL H HG13 1 
ATOM   3152 H HG21 . VAL A 1 215 ? 65.61100 -6.92400  2.78600   1.000 26.30539  ? 211 VAL H HG21 1 
ATOM   3153 H HG22 . VAL A 1 215 ? 65.91900 -7.92400  1.59100   1.000 26.30539  ? 211 VAL H HG22 1 
ATOM   3154 H HG23 . VAL A 1 215 ? 66.57900 -8.16200  3.01700   1.000 26.30539  ? 211 VAL H HG23 1 
ATOM   3155 N N    . GLU A 1 216 ? 70.20400 -6.70400  -0.31600  1.000 31.22849  ? 212 GLU H N    1 
ATOM   3156 C CA   . GLU A 1 216 ? 71.40300 -6.02100  -0.77400  1.000 35.11828  ? 212 GLU H CA   1 
ATOM   3157 C C    . GLU A 1 216 ? 71.05400 -4.82000  -1.64800  1.000 39.43861  ? 212 GLU H C    1 
ATOM   3158 O O    . GLU A 1 216 ? 70.00100 -4.79700  -2.29300  1.000 37.07801  ? 212 GLU H O    1 
ATOM   3159 C CB   . GLU A 1 216 ? 72.29900 -6.97100  -1.57700  1.000 38.53886  ? 212 GLU H CB   1 
ATOM   3160 C CG   . GLU A 1 216 ? 72.94100 -8.06600  -0.75100  1.000 37.36866  ? 212 GLU H CG   1 
ATOM   3161 C CD   . GLU A 1 216 ? 73.55100 -9.15300  -1.61100  1.000 43.21821  ? 212 GLU H CD   1 
ATOM   3162 O OE1  . GLU A 1 216 ? 73.24100 -9.19900  -2.82000  1.000 40.84916  ? 212 GLU H OE1  1 
ATOM   3163 O OE2  . GLU A 1 216 ? 74.33900 -9.96200  -1.08000  1.000 55.86801  ? 212 GLU H OE2  1 
ATOM   3164 H H    . GLU A 1 216 ? 69.79900 -7.13400  -0.94100  1.000 37.47776  ? 212 GLU H H    1 
ATOM   3165 H HA   . GLU A 1 216 ? 71.89900 -5.70100  -0.00400  1.000 42.14551  ? 212 GLU H HA   1 
ATOM   3166 H HB2  . GLU A 1 216 ? 71.76200 -7.39700  -2.26400  1.000 46.25020  ? 212 GLU H HB2  1 
ATOM   3167 H HB3  . GLU A 1 216 ? 73.01100 -6.45400  -1.98500  1.000 46.25020  ? 212 GLU H HB3  1 
ATOM   3168 H HG2  . GLU A 1 216 ? 73.64500 -7.68100  -0.20700  1.000 44.84596  ? 212 GLU H HG2  1 
ATOM   3169 H HG3  . GLU A 1 216 ? 72.26700 -8.47200  -0.18400  1.000 44.84596  ? 212 GLU H HG3  1 
ATOM   3170 N N    . PRO A 1 217 ? 71.92500 -3.81000  -1.69600  1.000 43.37853  ? 213 PRO H N    1 
ATOM   3171 C CA   . PRO A 1 217 ? 71.67100 -2.65700  -2.57000  1.000 45.12797  ? 213 PRO H CA   1 
ATOM   3172 C C    . PRO A 1 217 ? 71.47900 -3.05400  -4.02500  1.000 45.20789  ? 213 PRO H C    1 
ATOM   3173 O O    . PRO A 1 217 ? 72.03300 -4.04600  -4.50300  1.000 46.69852  ? 213 PRO H O    1 
ATOM   3174 C CB   . PRO A 1 217 ? 72.92900 -1.79700  -2.39400  1.000 52.10875  ? 213 PRO H CB   1 
ATOM   3175 C CG   . PRO A 1 217 ? 73.43000 -2.14300  -1.03300  1.000 50.56792  ? 213 PRO H CG   1 
ATOM   3176 C CD   . PRO A 1 217 ? 73.10000 -3.60000  -0.82700  1.000 45.93845  ? 213 PRO H CD   1 
ATOM   3177 H HA   . PRO A 1 217 ? 70.88500 -2.17800  -2.26400  1.000 54.15714  ? 213 PRO H HA   1 
ATOM   3178 H HB2  . PRO A 1 217 ? 73.58300 -2.02100  -3.07500  1.000 62.53407  ? 213 PRO H HB2  1 
ATOM   3179 H HB3  . PRO A 1 217 ? 72.69900 -0.85600  -2.45300  1.000 62.53407  ? 213 PRO H HB3  1 
ATOM   3180 H HG2  . PRO A 1 217 ? 74.38900 -2.00000  -0.99200  1.000 60.68508  ? 213 PRO H HG2  1 
ATOM   3181 H HG3  . PRO A 1 217 ? 72.98400 -1.59300  -0.37100  1.000 60.68508  ? 213 PRO H HG3  1 
ATOM   3182 H HD2  . PRO A 1 217 ? 73.83900 -4.16400  -1.10300  1.000 55.12971  ? 213 PRO H HD2  1 
ATOM   3183 H HD3  . PRO A 1 217 ? 72.87700 -3.77500  0.10100   1.000 55.12971  ? 213 PRO H HD3  1 
ATOM   3184 N N    . LYS A 1 218 ? 70.69200 -2.24100  -4.72800  1.000 49.67815  ? 214 LYS H N    1 
ATOM   3185 C CA   . LYS A 1 218 ? 70.37100 -2.42900  -6.14200  1.000 50.98861  ? 214 LYS H CA   1 
ATOM   3186 C C    . LYS A 1 218 ? 70.23500 -3.89500  -6.53200  1.000 50.24862  ? 214 LYS H C    1 
ATOM   3187 O O    . LYS A 1 218 ? 70.09900 -4.21800  -7.71300  1.000 55.31862  ? 214 LYS H O    1 
ATOM   3188 C CB   . LYS A 1 218 ? 71.43400 -1.75800  -7.02000  1.000 53.40888  ? 214 LYS H CB   1 
ATOM   3189 C CG   . LYS A 1 218 ? 72.62000 -2.64200  -7.36500  1.000 52.26795  ? 214 LYS H CG   1 
ATOM   3190 C CD   . LYS A 1 218 ? 73.69700 -1.84700  -8.08600  1.000 55.05825  ? 214 LYS H CD   1 
ATOM   3191 C CE   . LYS A 1 218 ? 74.57200 -2.75200  -8.93200  1.000 57.66860  ? 214 LYS H CE   1 
ATOM   3192 N NZ   . LYS A 1 218 ? 73.78300 -3.43700  -9.99600  1.000 47.76836  ? 214 LYS H NZ   1 
ATOM   3193 H H    . LYS A 1 218 ? 70.31600 -1.54300  -4.39500  1.000 59.61735  ? 214 LYS H H    1 
ATOM   3194 H HA   . LYS A 1 218 ? 69.50900 -2.01400  -6.30600  1.000 61.18990  ? 214 LYS H HA   1 
ATOM   3195 H HB2  . LYS A 1 218 ? 71.01900 -1.48700  -7.85400  1.000 64.09423  ? 214 LYS H HB2  1 
ATOM   3196 H HB3  . LYS A 1 218 ? 71.77600 -0.98100  -6.55100  1.000 64.09423  ? 214 LYS H HB3  1 
ATOM   3197 H HG2  . LYS A 1 218 ? 73.00000 -3.00600  -6.55000  1.000 62.72511  ? 214 LYS H HG2  1 
ATOM   3198 H HG3  . LYS A 1 218 ? 72.32900 -3.36200  -7.94500  1.000 62.72511  ? 214 LYS H HG3  1 
ATOM   3199 H HD2  . LYS A 1 218 ? 73.27900 -1.19300  -8.66800  1.000 66.07348  ? 214 LYS H HD2  1 
ATOM   3200 H HD3  . LYS A 1 218 ? 74.25900 -1.40100  -7.43300  1.000 66.07348  ? 214 LYS H HD3  1 
ATOM   3201 H HE2  . LYS A 1 218 ? 75.26300 -2.22200  -9.35900  1.000 69.20589  ? 214 LYS H HE2  1 
ATOM   3202 H HE3  . LYS A 1 218 ? 74.97500 -3.43000  -8.36700  1.000 69.20589  ? 214 LYS H HE3  1 
ATOM   3203 H HZ1  . LYS A 1 218 ? 74.31800 -3.67400  -10.66700 1.000 57.32560  ? 214 LYS H HZ1  1 
ATOM   3204 H HZ2  . LYS A 1 218 ? 73.39600 -4.16700  -9.66500  1.000 57.32560  ? 214 LYS H HZ2  1 
ATOM   3205 H HZ3  . LYS A 1 218 ? 73.15300 -2.89100  -10.30700 1.000 57.32560  ? 214 LYS H HZ3  1 
ATOM   3206 N N    . ASP B 2 1   ? 21.56700 -11.33600 30.09200  1.000 66.91843  ? 1   ASP L N    1 
ATOM   3207 C CA   . ASP B 2 1   ? 22.92100 -11.02600 29.55000  1.000 58.61845  ? 1   ASP L CA   1 
ATOM   3208 C C    . ASP B 2 1   ? 23.50700 -9.80900  30.26200  1.000 51.05794  ? 1   ASP L C    1 
ATOM   3209 O O    . ASP B 2 1   ? 22.80000 -8.84300  30.54800  1.000 51.40832  ? 1   ASP L O    1 
ATOM   3210 C CB   . ASP B 2 1   ? 22.85200 -10.78000 28.04200  1.000 61.82793  ? 1   ASP L CB   1 
ATOM   3211 C CG   . ASP B 2 1   ? 24.21900 -10.79000 27.38500  1.000 65.51795  ? 1   ASP L CG   1 
ATOM   3212 O OD1  . ASP B 2 1   ? 25.22300 -11.02600 28.09100  1.000 63.04749  ? 1   ASP L OD1  1 
ATOM   3213 O OD2  . ASP B 2 1   ? 24.28800 -10.56500 26.15900  1.000 64.91857  ? 1   ASP L OD2  1 
ATOM   3214 H H1   . ASP B 2 1   ? 21.01200 -11.51700 29.41900  1.000 80.30569  ? 1   ASP L H1   1 
ATOM   3215 H H2   . ASP B 2 1   ? 21.61800 -12.04200 30.63100  1.000 80.30569  ? 1   ASP L H2   1 
ATOM   3216 H H3   . ASP B 2 1   ? 21.26200 -10.63500 30.54800  1.000 80.30569  ? 1   ASP L H3   1 
ATOM   3217 H HA   . ASP B 2 1   ? 23.51300 -11.78000 29.69500  1.000 70.34571  ? 1   ASP L HA   1 
ATOM   3218 H HB2  . ASP B 2 1   ? 22.31600 -11.47800 27.63300  1.000 74.19708  ? 1   ASP L HB2  1 
ATOM   3219 H HB3  . ASP B 2 1   ? 22.44700 -9.91400  27.88100  1.000 74.19708  ? 1   ASP L HB3  1 
ATOM   3220 N N    . ILE B 2 2   ? 24.80400 -9.86700  30.54300  1.000 47.36820  ? 2   ILE L N    1 
ATOM   3221 C CA   . ILE B 2 2   ? 25.50600 -8.83100  31.29100  1.000 41.30777  ? 2   ILE L CA   1 
ATOM   3222 C C    . ILE B 2 2   ? 26.29000 -7.97200  30.31200  1.000 38.82901  ? 2   ILE L C    1 
ATOM   3223 O O    . ILE B 2 2   ? 26.92900 -8.48900  29.38700  1.000 39.97868  ? 2   ILE L O    1 
ATOM   3224 C CB   . ILE B 2 2   ? 26.43200 -9.45700  32.35100  1.000 38.78791  ? 2   ILE L CB   1 
ATOM   3225 C CG1  . ILE B 2 2   ? 25.61600 -10.33100 33.30700  1.000 40.18737  ? 2   ILE L CG1  1 
ATOM   3226 C CG2  . ILE B 2 2   ? 27.17300 -8.37400  33.11500  1.000 38.90931  ? 2   ILE L CG2  1 
ATOM   3227 C CD1  . ILE B 2 2   ? 26.44500 -11.32900 34.08900  1.000 42.64816  ? 2   ILE L CD1  1 
ATOM   3228 H H    . ILE B 2 2   ? 25.31400 -10.51600 30.30300  1.000 56.84541  ? 2   ILE L H    1 
ATOM   3229 H HA   . ILE B 2 2   ? 24.86400 -8.26300  31.74500  1.000 49.57289  ? 2   ILE L HA   1 
ATOM   3230 H HB   . ILE B 2 2   ? 27.08600 -10.01500 31.90200  1.000 46.54906  ? 2   ILE L HB   1 
ATOM   3231 H HG12 . ILE B 2 2   ? 25.16500 -9.75700  33.94600  1.000 48.22841  ? 2   ILE L HG12 1 
ATOM   3232 H HG13 . ILE B 2 2   ? 24.96200 -10.83000 32.79200  1.000 48.22841  ? 2   ILE L HG13 1 
ATOM   3233 H HG21 . ILE B 2 2   ? 27.67600 -8.78400  33.83600  1.000 46.69474  ? 2   ILE L HG21 1 
ATOM   3234 H HG22 . ILE B 2 2   ? 27.77700 -7.91800  32.50900  1.000 46.69474  ? 2   ILE L HG22 1 
ATOM   3235 H HG23 . ILE B 2 2   ? 26.52900 -7.74600  33.47700  1.000 46.69474  ? 2   ILE L HG23 1 
ATOM   3236 H HD11 . ILE B 2 2   ? 25.85900 -11.84600 34.66300  1.000 51.18136  ? 2   ILE L HD11 1 
ATOM   3237 H HD12 . ILE B 2 2   ? 26.90200 -11.91700 33.46600  1.000 51.18136  ? 2   ILE L HD12 1 
ATOM   3238 H HD13 . ILE B 2 2   ? 27.09400 -10.84800 34.62600  1.000 51.18136  ? 2   ILE L HD13 1 
ATOM   3239 N N    . GLN B 2 3   ? 26.24700 -6.65800  30.51600  1.000 32.12672  ? 3   GLN L N    1 
ATOM   3240 C CA   . GLN B 2 3   ? 26.83300 -5.70600  29.58600  1.000 32.65808  ? 3   GLN L CA   1 
ATOM   3241 C C    . GLN B 2 3   ? 27.64400 -4.66400  30.34000  1.000 31.33871  ? 3   GLN L C    1 
ATOM   3242 O O    . GLN B 2 3   ? 27.27000 -4.24100  31.43700  1.000 28.10668  ? 3   GLN L O    1 
ATOM   3243 C CB   . GLN B 2 3   ? 25.74200 -5.01500  28.76200  1.000 34.72765  ? 3   GLN L CB   1 
ATOM   3244 C CG   . GLN B 2 3   ? 26.08100 -4.83900  27.29900  1.000 44.92934  ? 3   GLN L CG   1 
ATOM   3245 C CD   . GLN B 2 3   ? 24.84900 -4.57800  26.45500  1.000 50.72786  ? 3   GLN L CD   1 
ATOM   3246 O OE1  . GLN B 2 3   ? 24.48100 -3.42800  26.21200  1.000 50.01923  ? 3   GLN L OE1  1 
ATOM   3247 N NE2  . GLN B 2 3   ? 24.19900 -5.64900  26.01000  1.000 52.58817  ? 3   GLN L NE2  1 
ATOM   3248 H H    . GLN B 2 3   ? 25.87700 -6.29000  31.20000  1.000 38.55564  ? 3   GLN L H    1 
ATOM   3249 H HA   . GLN B 2 3   ? 27.43700 -6.17100  28.98700  1.000 39.19326  ? 3   GLN L HA   1 
ATOM   3250 H HB2  . GLN B 2 3   ? 24.93200 -5.54700  28.81400  1.000 41.67676  ? 3   GLN L HB2  1 
ATOM   3251 H HB3  . GLN B 2 3   ? 25.58400 -4.13300  29.13500  1.000 41.67676  ? 3   GLN L HB3  1 
ATOM   3252 H HG2  . GLN B 2 3   ? 26.68100 -4.08300  27.20000  1.000 53.91878  ? 3   GLN L HG2  1 
ATOM   3253 H HG3  . GLN B 2 3   ? 26.50700 -5.64600  26.97100  1.000 53.91878  ? 3   GLN L HG3  1 
ATOM   3254 H HE21 . GLN B 2 3   ? 24.48400 -6.43600  26.20600  1.000 63.10938  ? 3   GLN L HE21 1 
ATOM   3255 H HE22 . GLN B 2 3   ? 23.49400 -5.55400  25.52700  1.000 63.10938  ? 3   GLN L HE22 1 
ATOM   3256 N N    . MET B 2 4   ? 28.75900 -4.25700  29.74100  1.000 29.30776  ? 4   MET L N    1 
ATOM   3257 C CA   . MET B 2 4   ? 29.56800 -3.15300  30.24300  1.000 26.60608  ? 4   MET L CA   1 
ATOM   3258 C C    . MET B 2 4   ? 29.73900 -2.15700  29.10900  1.000 29.74902  ? 4   MET L C    1 
ATOM   3259 O O    . MET B 2 4   ? 30.17500 -2.52700  28.01400  1.000 24.39584  ? 4   MET L O    1 
ATOM   3260 C CB   . MET B 2 4   ? 30.91200 -3.65500  30.76800  1.000 27.23732  ? 4   MET L CB   1 
ATOM   3261 C CG   . MET B 2 4   ? 30.73800 -4.59200  31.95700  1.000 30.86942  ? 4   MET L CG   1 
ATOM   3262 S SD   . MET B 2 4   ? 32.26100 -5.28500  32.60700  1.000 32.23118  ? 4   MET L SD   1 
ATOM   3263 C CE   . MET B 2 4   ? 32.89900 -3.90300  33.54300  1.000 30.03871  ? 4   MET L CE   1 
ATOM   3264 H H    . MET B 2 4   ? 29.07400 -4.61300  29.02500  1.000 35.17289  ? 4   MET L H    1 
ATOM   3265 H HA   . MET B 2 4   ? 29.12000 -2.71400  30.98400  1.000 31.93087  ? 4   MET L HA   1 
ATOM   3266 H HB2  . MET B 2 4   ? 31.37000 -4.13800  30.06300  1.000 32.68835  ? 4   MET L HB2  1 
ATOM   3267 H HB3  . MET B 2 4   ? 31.44700 -2.89700  31.05300  1.000 32.68835  ? 4   MET L HB3  1 
ATOM   3268 H HG2  . MET B 2 4   ? 30.31400 -4.09900  32.67700  1.000 37.04687  ? 4   MET L HG2  1 
ATOM   3269 H HG3  . MET B 2 4   ? 30.17500 -5.33300  31.68500  1.000 37.04687  ? 4   MET L HG3  1 
ATOM   3270 H HE1  . MET B 2 4   ? 33.58800 -4.22100  34.14600  1.000 36.05002  ? 4   MET L HE1  1 
ATOM   3271 H HE2  . MET B 2 4   ? 33.27100 -3.25100  32.92900  1.000 36.05002  ? 4   MET L HE2  1 
ATOM   3272 H HE3  . MET B 2 4   ? 32.17400 -3.50400  34.04900  1.000 36.05002  ? 4   MET L HE3  1 
ATOM   3273 N N    . THR B 2 5   ? 29.36700 -0.90800  29.36400  1.000 29.40817  ? 5   THR L N    1 
ATOM   3274 C CA   . THR B 2 5   ? 29.31500 0.13400   28.34600  1.000 29.29815  ? 5   THR L CA   1 
ATOM   3275 C C    . THR B 2 5   ? 30.39200 1.16200   28.66000  1.000 28.81905  ? 5   THR L C    1 
ATOM   3276 O O    . THR B 2 5   ? 30.30500 1.87100   29.66800  1.000 27.30777  ? 5   THR L O    1 
ATOM   3277 C CB   . THR B 2 5   ? 27.93400 0.78400   28.31200  1.000 30.70880  ? 5   THR L CB   1 
ATOM   3278 O OG1  . THR B 2 5   ? 26.93200 -0.22500  28.13500  1.000 33.02774  ? 5   THR L OG1  1 
ATOM   3279 C CG2  . THR B 2 5   ? 27.84200 1.79200   27.18400  1.000 27.16883  ? 5   THR L CG2  1 
ATOM   3280 H H    . THR B 2 5   ? 29.13200 -0.63200  30.14400  1.000 35.29337  ? 5   THR L H    1 
ATOM   3281 H HA   . THR B 2 5   ? 29.50000 -0.25300  27.47600  1.000 35.16135  ? 5   THR L HA   1 
ATOM   3282 H HB   . THR B 2 5   ? 27.77800 1.25200   29.14700  1.000 36.85413  ? 5   THR L HB   1 
ATOM   3283 H HG1  . THR B 2 5   ? 26.78200 -0.61200  28.86500  1.000 39.63685  ? 5   THR L HG1  1 
ATOM   3284 H HG21 . THR B 2 5   ? 26.95500 2.18300   27.16000  1.000 32.60616  ? 5   THR L HG21 1 
ATOM   3285 H HG22 . THR B 2 5   ? 28.49400 2.49700   27.31500  1.000 32.60616  ? 5   THR L HG22 1 
ATOM   3286 H HG23 . THR B 2 5   ? 28.01600 1.35600   26.33500  1.000 32.60616  ? 5   THR L HG23 1 
ATOM   3287 N N    . GLN B 2 6   ? 31.40300 1.24000   27.80300  1.000 24.96582  ? 6   GLN L N    1 
ATOM   3288 C CA   . GLN B 2 6   ? 32.45000 2.23400   27.96300  1.000 26.72752  ? 6   GLN L CA   1 
ATOM   3289 C C    . GLN B 2 6   ? 32.12300 3.47200   27.14400  1.000 29.39909  ? 6   GLN L C    1 
ATOM   3290 O O    . GLN B 2 6   ? 31.45200 3.40100   26.11100  1.000 29.17820  ? 6   GLN L O    1 
ATOM   3291 C CB   . GLN B 2 6   ? 33.80700 1.68600   27.52500  1.000 25.95816  ? 6   GLN L CB   1 
ATOM   3292 C CG   . GLN B 2 6   ? 34.25300 0.46000   28.27600  1.000 26.75919  ? 6   GLN L CG   1 
ATOM   3293 C CD   . GLN B 2 6   ? 35.64200 0.01000   27.87500  1.000 22.43823  ? 6   GLN L CD   1 
ATOM   3294 O OE1  . GLN B 2 6   ? 35.93500 -1.18100  27.87300  1.000 20.73857  ? 6   GLN L OE1  1 
ATOM   3295 N NE2  . GLN B 2 6   ? 36.50800 0.95900   27.54500  1.000 19.69638  ? 6   GLN L NE2  1 
ATOM   3296 H H    . GLN B 2 6   ? 31.50300 0.72700   27.12100  1.000 29.96255  ? 6   GLN L H    1 
ATOM   3297 H HA   . GLN B 2 6   ? 32.51400 2.47700   28.90000  1.000 32.07660  ? 6   GLN L HA   1 
ATOM   3298 H HB2  . GLN B 2 6   ? 33.75700 1.45300   26.58500  1.000 31.15336  ? 6   GLN L HB2  1 
ATOM   3299 H HB3  . GLN B 2 6   ? 34.47700 2.37400   27.66100  1.000 31.15336  ? 6   GLN L HB3  1 
ATOM   3300 H HG2  . GLN B 2 6   ? 34.26200 0.65600   29.22600  1.000 32.11460  ? 6   GLN L HG2  1 
ATOM   3301 H HG3  . GLN B 2 6   ? 33.63600 -0.26600  28.09300  1.000 32.11460  ? 6   GLN L HG3  1 
ATOM   3302 H HE21 . GLN B 2 6   ? 36.26800 1.78500   27.56500  1.000 23.63923  ? 6   GLN L HE21 1 
ATOM   3303 H HE22 . GLN B 2 6   ? 37.30800 0.74900   27.31100  1.000 23.63923  ? 6   GLN L HE22 1 
ATOM   3304 N N    . SER B 2 7   ? 32.62000 4.61400   27.61200  1.000 30.02900  ? 7   SER L N    1 
ATOM   3305 C CA   . SER B 2 7   ? 32.46900 5.85600   26.88800  1.000 29.41785  ? 7   SER L CA   1 
ATOM   3306 C C    . SER B 2 7   ? 33.62900 6.76900   27.24500  1.000 29.52863  ? 7   SER L C    1 
ATOM   3307 O O    . SER B 2 7   ? 34.04900 6.79800   28.41100  1.000 28.95841  ? 7   SER L O    1 
ATOM   3308 C CB   . SER B 2 7   ? 31.14000 6.54100   27.21600  1.000 30.78866  ? 7   SER L CB   1 
ATOM   3309 O OG   . SER B 2 7   ? 30.92900 6.58400   28.61400  1.000 35.49929  ? 7   SER L OG   1 
ATOM   3310 H H    . SER B 2 7   ? 33.05000 4.68800   28.35200  1.000 36.03838  ? 7   SER L H    1 
ATOM   3311 H HA   . SER B 2 7   ? 32.50300 5.68200   25.93500  1.000 35.30499  ? 7   SER L HA   1 
ATOM   3312 H HB2  . SER B 2 7   ? 31.15800 7.44700   26.87100  1.000 36.94996  ? 7   SER L HB2  1 
ATOM   3313 H HB3  . SER B 2 7   ? 30.41700 6.04300   26.80300  1.000 36.94996  ? 7   SER L HB3  1 
ATOM   3314 H HG   . SER B 2 7   ? 31.59300 6.92900   28.99400  1.000 42.60272  ? 7   SER L HG   1 
ATOM   3315 N N    . PRO B 2 8   ? 34.18900 7.49900   26.27000  1.000 29.34885  ? 8   PRO L N    1 
ATOM   3316 C CA   . PRO B 2 8   ? 33.83900 7.40100   24.84700  1.000 27.94784  ? 8   PRO L CA   1 
ATOM   3317 C C    . PRO B 2 8   ? 34.32200 6.09100   24.22000  1.000 30.12961  ? 8   PRO L C    1 
ATOM   3318 O O    . PRO B 2 8   ? 35.07900 5.35400   24.85300  1.000 28.34859  ? 8   PRO L O    1 
ATOM   3319 C CB   . PRO B 2 8   ? 34.55700 8.60200   24.22900  1.000 29.14888  ? 8   PRO L CB   1 
ATOM   3320 C CG   . PRO B 2 8   ? 35.71300 8.84900   25.13300  1.000 28.51806  ? 8   PRO L CG   1 
ATOM   3321 C CD   . PRO B 2 8   ? 35.23300 8.51100   26.51400  1.000 27.60836  ? 8   PRO L CD   1 
ATOM   3322 H HA   . PRO B 2 8   ? 32.88300 7.49200   24.71200  1.000 33.54098  ? 8   PRO L HA   1 
ATOM   3323 H HB2  . PRO B 2 8   ? 34.85500 8.38500   23.33200  1.000 34.98222  ? 8   PRO L HB2  1 
ATOM   3324 H HB3  . PRO B 2 8   ? 33.96200 9.36800   24.20400  1.000 34.98222  ? 8   PRO L HB3  1 
ATOM   3325 H HG2  . PRO B 2 8   ? 36.45500 8.28000   24.87800  1.000 34.22524  ? 8   PRO L HG2  1 
ATOM   3326 H HG3  . PRO B 2 8   ? 35.97600 9.78200   25.07900  1.000 34.22524  ? 8   PRO L HG3  1 
ATOM   3327 H HD2  . PRO B 2 8   ? 35.95400 8.14200   27.04900  1.000 33.13360  ? 8   PRO L HD2  1 
ATOM   3328 H HD3  . PRO B 2 8   ? 34.86200 9.29200   26.95200  1.000 33.13360  ? 8   PRO L HD3  1 
ATOM   3329 N N    . SER B 2 9   ? 33.86200 5.80100   22.99800  1.000 29.51901  ? 9   SER L N    1 
ATOM   3330 C CA   . SER B 2 9   ? 34.41200 4.68100   22.24300  1.000 27.55825  ? 9   SER L CA   1 
ATOM   3331 C C    . SER B 2 9   ? 35.80000 5.00500   21.70500  1.000 26.35779  ? 9   SER L C    1 
ATOM   3332 O O    . SER B 2 9   ? 36.59600 4.09500   21.45000  1.000 25.31779  ? 9   SER L O    1 
ATOM   3333 C CB   . SER B 2 9   ? 33.48100 4.30800   21.08900  1.000 30.80896  ? 9   SER L CB   1 
ATOM   3334 O OG   . SER B 2 9   ? 32.29700 3.68900   21.56100  1.000 35.12934  ? 9   SER L OG   1 
ATOM   3335 H H    . SER B 2 9   ? 33.23900 6.23300   22.59200  1.000 35.42638  ? 9   SER L H    1 
ATOM   3336 H HA   . SER B 2 9   ? 34.48100 3.91300   22.83300  1.000 33.07347  ? 9   SER L HA   1 
ATOM   3337 H HB2  . SER B 2 9   ? 33.24300 5.11400   20.60600  1.000 36.97432  ? 9   SER L HB2  1 
ATOM   3338 H HB3  . SER B 2 9   ? 33.94400 3.69200   20.50000  1.000 36.97432  ? 9   SER L HB3  1 
ATOM   3339 H HG   . SER B 2 9   ? 31.83800 3.41600   20.91200  1.000 42.15878  ? 9   SER L HG   1 
ATOM   3340 N N    . SER B 2 10  ? 36.09800 6.28600   21.50800  1.000 27.97842  ? 10  SER L N    1 
ATOM   3341 C CA   . SER B 2 10  ? 37.43800 6.71000   21.13100  1.000 28.01835  ? 10  SER L CA   1 
ATOM   3342 C C    . SER B 2 10  ? 37.60300 8.17100   21.51800  1.000 29.57848  ? 10  SER L C    1 
ATOM   3343 O O    . SER B 2 10  ? 36.62400 8.90300   21.68500  1.000 26.55587  ? 10  SER L O    1 
ATOM   3344 C CB   . SER B 2 10  ? 37.69800 6.52100   19.63500  1.000 28.94888  ? 10  SER L CB   1 
ATOM   3345 O OG   . SER B 2 10  ? 36.90100 7.40400   18.87000  1.000 32.51963  ? 10  SER L OG   1 
ATOM   3346 H H    . SER B 2 10  ? 35.53700 6.93300   21.58800  1.000 33.57767  ? 10  SER L H    1 
ATOM   3347 H HA   . SER B 2 10  ? 38.09000 6.18100   21.61700  1.000 33.62559  ? 10  SER L HA   1 
ATOM   3348 H HB2  . SER B 2 10  ? 38.63300 6.70200   19.45200  1.000 34.74223  ? 10  SER L HB2  1 
ATOM   3349 H HB3  . SER B 2 10  ? 37.48200 5.60800   19.39000  1.000 34.74223  ? 10  SER L HB3  1 
ATOM   3350 H HG   . SER B 2 10  ? 37.13400 7.37700   18.06400  1.000 39.02713  ? 10  SER L HG   1 
ATOM   3351 N N    . LEU B 2 11  ? 38.85800 8.58200   21.66300  1.000 28.25671  ? 11  LEU L N    1 
ATOM   3352 C CA   . LEU B 2 11  ? 39.17100 9.95800   22.00600  1.000 31.12853  ? 11  LEU L CA   1 
ATOM   3353 C C    . LEU B 2 11  ? 40.55600 10.28900  21.47500  1.000 33.27861  ? 11  LEU L C    1 
ATOM   3354 O O    . LEU B 2 11  ? 41.39300 9.40400   21.28400  1.000 32.39871  ? 11  LEU L O    1 
ATOM   3355 C CB   . LEU B 2 11  ? 39.10400 10.18700  23.51900  1.000 29.90785  ? 11  LEU L CB   1 
ATOM   3356 C CG   . LEU B 2 11  ? 40.14700 9.44100   24.35000  1.000 31.89775  ? 11  LEU L CG   1 
ATOM   3357 C CD1  . LEU B 2 11  ? 41.38400 10.30000  24.57800  1.000 33.47839  ? 11  LEU L CD1  1 
ATOM   3358 C CD2  . LEU B 2 11  ? 39.54700 8.98800   25.67800  1.000 34.52778  ? 11  LEU L CD2  1 
ATOM   3359 H H    . LEU B 2 11  ? 39.54800 8.07800   21.56700  1.000 33.91163  ? 11  LEU L H    1 
ATOM   3360 H HA   . LEU B 2 11  ? 38.53500 10.55700  21.58500  1.000 37.35781  ? 11  LEU L HA   1 
ATOM   3361 H HB2  . LEU B 2 11  ? 39.22500 11.13500  23.68800  1.000 35.89299  ? 11  LEU L HB2  1 
ATOM   3362 H HB3  . LEU B 2 11  ? 38.23000 9.90300   23.83000  1.000 35.89299  ? 11  LEU L HB3  1 
ATOM   3363 H HG   . LEU B 2 11  ? 40.42800 8.65100   23.86100  1.000 38.28087  ? 11  LEU L HG   1 
ATOM   3364 H HD11 . LEU B 2 11  ? 41.99900 9.82100   25.15500  1.000 40.17764  ? 11  LEU L HD11 1 
ATOM   3365 H HD12 . LEU B 2 11  ? 41.80500 10.48000  23.72300  1.000 40.17764  ? 11  LEU L HD12 1 
ATOM   3366 H HD13 . LEU B 2 11  ? 41.11700 11.13300  24.99700  1.000 40.17764  ? 11  LEU L HD13 1 
ATOM   3367 H HD21 . LEU B 2 11  ? 40.23100 8.53400   26.19500  1.000 41.43691  ? 11  LEU L HD21 1 
ATOM   3368 H HD22 . LEU B 2 11  ? 39.22800 9.76500   26.16200  1.000 41.43691  ? 11  LEU L HD22 1 
ATOM   3369 H HD23 . LEU B 2 11  ? 38.81000 8.38300   25.50200  1.000 41.43691  ? 11  LEU L HD23 1 
ATOM   3370 N N    . SER B 2 12  ? 40.77900 11.57400  21.22800  1.000 33.32786  ? 12  SER L N    1 
ATOM   3371 C CA   . SER B 2 12  ? 42.06700 12.09500  20.79700  1.000 35.62899  ? 12  SER L CA   1 
ATOM   3372 C C    . SER B 2 12  ? 42.50700 13.12300  21.82600  1.000 32.68688  ? 12  SER L C    1 
ATOM   3373 O O    . SER B 2 12  ? 41.75000 14.04500  22.14200  1.000 32.84602  ? 12  SER L O    1 
ATOM   3374 C CB   . SER B 2 12  ? 41.96900 12.71900  19.40200  1.000 36.94863  ? 12  SER L CB   1 
ATOM   3375 O OG   . SER B 2 12  ? 43.25300 12.93000  18.84000  1.000 39.54860  ? 12  SER L OG   1 
ATOM   3376 H H    . SER B 2 12  ? 40.17800 12.18400  21.30700  1.000 39.99701  ? 12  SER L H    1 
ATOM   3377 H HA   . SER B 2 12  ? 42.73000 11.38900  20.74900  1.000 42.75836  ? 12  SER L HA   1 
ATOM   3378 H HB2  . SER B 2 12  ? 41.46900 12.12100  18.82500  1.000 44.34193  ? 12  SER L HB2  1 
ATOM   3379 H HB3  . SER B 2 12  ? 41.51300 13.57200  19.47100  1.000 44.34193  ? 12  SER L HB3  1 
ATOM   3380 H HG   . SER B 2 12  ? 43.17900 13.20600  18.05000  1.000 47.46190  ? 12  SER L HG   1 
ATOM   3381 N N    . ALA B 2 13  ? 43.70900 12.94700  22.37100  1.000 31.79792  ? 13  ALA L N    1 
ATOM   3382 C CA   . ALA B 2 13  ? 44.21600 13.82800  23.41300  1.000 29.80724  ? 13  ALA L CA   1 
ATOM   3383 C C    . ALA B 2 13  ? 45.68600 14.12300  23.16300  1.000 31.65824  ? 13  ALA L C    1 
ATOM   3384 O O    . ALA B 2 13  ? 46.39400 13.35000  22.51200  1.000 30.44807  ? 13  ALA L O    1 
ATOM   3385 C CB   . ALA B 2 13  ? 44.03200 13.21400  24.80800  1.000 32.79945  ? 13  ALA L CB   1 
ATOM   3386 H H    . ALA B 2 13  ? 44.25300 12.31800  22.15100  1.000 38.16108  ? 13  ALA L H    1 
ATOM   3387 H HA   . ALA B 2 13  ? 43.73300 14.66900  23.38000  1.000 35.77226  ? 13  ALA L HA   1 
ATOM   3388 H HB1  . ALA B 2 13  ? 44.45000 13.79100  25.46500  1.000 39.36291  ? 13  ALA L HB1  1 
ATOM   3389 H HB2  . ALA B 2 13  ? 43.08300 13.13300  24.99500  1.000 39.36291  ? 13  ALA L HB2  1 
ATOM   3390 H HB3  . ALA B 2 13  ? 44.44800 12.33800  24.82400  1.000 39.36291  ? 13  ALA L HB3  1 
ATOM   3391 N N    . SER B 2 14  ? 46.14000 15.25600  23.69400  1.000 32.89843  ? 14  SER L N    1 
ATOM   3392 C CA   . SER B 2 14  ? 47.52300 15.68200  23.55100  1.000 26.67506  ? 14  SER L CA   1 
ATOM   3393 C C    . SER B 2 14  ? 48.35600 15.17600  24.72100  1.000 29.80793  ? 14  SER L C    1 
ATOM   3394 O O    . SER B 2 14  ? 47.84600 14.94000  25.81800  1.000 29.83699  ? 14  SER L O    1 
ATOM   3395 C CB   . SER B 2 14  ? 47.61900 17.20700  23.46700  1.000 31.85869  ? 14  SER L CB   1 
ATOM   3396 O OG   . SER B 2 14  ? 47.11900 17.68700  22.23100  1.000 34.58800  ? 14  SER L OG   1 
ATOM   3397 H H    . SER B 2 14  ? 45.65500 15.80200  24.14900  1.000 39.48169  ? 14  SER L H    1 
ATOM   3398 H HA   . SER B 2 14  ? 47.88800 15.31300  22.73100  1.000 32.01364  ? 14  SER L HA   1 
ATOM   3399 H HB2  . SER B 2 14  ? 47.09800 17.59400  24.18800  1.000 38.23400  ? 14  SER L HB2  1 
ATOM   3400 H HB3  . SER B 2 14  ? 48.54900 17.46800  23.55300  1.000 38.23400  ? 14  SER L HB3  1 
ATOM   3401 H HG   . SER B 2 14  ? 47.21400 18.52100  22.18700  1.000 41.50918  ? 14  SER L HG   1 
ATOM   3402 N N    . VAL B 2 15  ? 49.65500 15.00200  24.46900  1.000 27.48612  ? 15  VAL L N    1 
ATOM   3403 C CA   . VAL B 2 15  ? 50.55700 14.57000  25.52800  1.000 28.78695  ? 15  VAL L CA   1 
ATOM   3404 C C    . VAL B 2 15  ? 50.45000 15.54300  26.69500  1.000 31.18767  ? 15  VAL L C    1 
ATOM   3405 O O    . VAL B 2 15  ? 50.31500 16.76000  26.50700  1.000 31.32798  ? 15  VAL L O    1 
ATOM   3406 C CB   . VAL B 2 15  ? 51.99400 14.46800  24.99200  1.000 30.53789  ? 15  VAL L CB   1 
ATOM   3407 C CG1  . VAL B 2 15  ? 52.96700 14.13500  26.11000  1.000 31.20832  ? 15  VAL L CG1  1 
ATOM   3408 C CG2  . VAL B 2 15  ? 52.07400 13.41400  23.89600  1.000 31.61811  ? 15  VAL L CG2  1 
ATOM   3409 H H    . VAL B 2 15  ? 50.03000 15.12600  23.70500  1.000 32.98692  ? 15  VAL L H    1 
ATOM   3410 H HA   . VAL B 2 15  ? 50.30000 13.68900  25.84200  1.000 34.54791  ? 15  VAL L HA   1 
ATOM   3411 H HB   . VAL B 2 15  ? 52.24600 15.32700  24.61900  1.000 36.64904  ? 15  VAL L HB   1 
ATOM   3412 H HG11 . VAL B 2 15  ? 53.83800 13.95000  25.72600  1.000 37.45355  ? 15  VAL L HG11 1 
ATOM   3413 H HG12 . VAL B 2 15  ? 53.02600 14.89100  26.71400  1.000 37.45355  ? 15  VAL L HG12 1 
ATOM   3414 H HG13 . VAL B 2 15  ? 52.64400 13.35500  26.58800  1.000 37.45355  ? 15  VAL L HG13 1 
ATOM   3415 H HG21 . VAL B 2 15  ? 52.98900 13.35800  23.57700  1.000 37.94530  ? 15  VAL L HG21 1 
ATOM   3416 H HG22 . VAL B 2 15  ? 51.79800 12.55800  24.25900  1.000 37.94530  ? 15  VAL L HG22 1 
ATOM   3417 H HG23 . VAL B 2 15  ? 51.48600 13.66900  23.16800  1.000 37.94530  ? 15  VAL L HG23 1 
ATOM   3418 N N    . GLY B 2 16  ? 50.48400 15.00400  27.91300  1.000 30.88639  ? 16  GLY L N    1 
ATOM   3419 C CA   . GLY B 2 16  ? 50.28300 15.79200  29.10800  1.000 34.61855  ? 16  GLY L CA   1 
ATOM   3420 C C    . GLY B 2 16  ? 48.83600 15.98700  29.50700  1.000 35.93940  ? 16  GLY L C    1 
ATOM   3421 O O    . GLY B 2 16  ? 48.57300 16.39800  30.64500  1.000 34.06728  ? 16  GLY L O    1 
ATOM   3422 H H    . GLY B 2 16  ? 50.62600 14.17000  28.06700  1.000 37.06724  ? 16  GLY L H    1 
ATOM   3423 H HA2  . GLY B 2 16  ? 50.73700 15.35700  29.84600  1.000 41.54583  ? 16  GLY L HA2  1 
ATOM   3424 H HA3  . GLY B 2 16  ? 50.67300 16.66900  28.97100  1.000 41.54583  ? 16  GLY L HA3  1 
ATOM   3425 N N    . ASP B 2 17  ? 47.89100 15.70600  28.61500  1.000 32.96751  ? 17  ASP L N    1 
ATOM   3426 C CA   . ASP B 2 17  ? 46.48700 15.88400  28.94000  1.000 34.36806  ? 17  ASP L CA   1 
ATOM   3427 C C    . ASP B 2 17  ? 46.02300 14.84600  29.95800  1.000 34.72875  ? 17  ASP L C    1 
ATOM   3428 O O    . ASP B 2 17  ? 46.65500 13.80800  30.17400  1.000 33.71819  ? 17  ASP L O    1 
ATOM   3429 C CB   . ASP B 2 17  ? 45.61800 15.77800  27.68800  1.000 33.77829  ? 17  ASP L CB   1 
ATOM   3430 C CG   . ASP B 2 17  ? 45.69500 17.00900  26.81800  1.000 36.19950  ? 17  ASP L CG   1 
ATOM   3431 O OD1  . ASP B 2 17  ? 46.41800 17.95900  27.18600  1.000 39.05954  ? 17  ASP L OD1  1 
ATOM   3432 O OD2  . ASP B 2 17  ? 45.02600 17.02100  25.76300  1.000 36.02852  ? 17  ASP L OD2  1 
ATOM   3433 H H    . ASP B 2 17  ? 48.03800 15.41200  27.82000  1.000 39.56459  ? 17  ASP L H    1 
ATOM   3434 H HA   . ASP B 2 17  ? 46.37200 16.76800  29.32400  1.000 41.24525  ? 17  ASP L HA   1 
ATOM   3435 H HB2  . ASP B 2 17  ? 45.91300 15.01900  27.16100  1.000 40.53752  ? 17  ASP L HB2  1 
ATOM   3436 H HB3  . ASP B 2 17  ? 44.69300 15.65600  27.95500  1.000 40.53752  ? 17  ASP L HB3  1 
ATOM   3437 N N    . ARG B 2 18  ? 44.88800 15.14400  30.57800  1.000 35.45838  ? 18  ARG L N    1 
ATOM   3438 C CA   . ARG B 2 18  ? 44.22100 14.24800  31.51200  1.000 35.14704  ? 18  ARG L CA   1 
ATOM   3439 C C    . ARG B 2 18  ? 43.08600 13.54500  30.78000  1.000 33.94805  ? 18  ARG L C    1 
ATOM   3440 O O    . ARG B 2 18  ? 42.24800 14.20100  30.15200  1.000 32.52670  ? 18  ARG L O    1 
ATOM   3441 C CB   . ARG B 2 18  ? 43.69900 15.04200  32.70600  1.000 38.71881  ? 18  ARG L CB   1 
ATOM   3442 C CG   . ARG B 2 18  ? 42.89500 14.26500  33.71700  1.000 36.60905  ? 18  ARG L CG   1 
ATOM   3443 C CD   . ARG B 2 18  ? 42.31100 15.23600  34.73300  1.000 40.28847  ? 18  ARG L CD   1 
ATOM   3444 N NE   . ARG B 2 18  ? 41.61600 14.56300  35.82100  1.000 45.98840  ? 18  ARG L NE   1 
ATOM   3445 C CZ   . ARG B 2 18  ? 42.20900 14.08900  36.90800  1.000 48.06758  ? 18  ARG L CZ   1 
ATOM   3446 N NH1  . ARG B 2 18  ? 43.52200 14.15200  37.06300  1.000 44.86624  ? 18  ARG L NH1  1 
ATOM   3447 N NH2  . ARG B 2 18  ? 41.46500 13.54000  37.86300  1.000 47.81797  ? 18  ARG L NH2  1 
ATOM   3448 H H    . ARG B 2 18  ? 44.47000 15.88800  30.47000  1.000 42.55363  ? 18  ARG L H    1 
ATOM   3449 H HA   . ARG B 2 18  ? 44.83100 13.57000  31.84400  1.000 42.18002  ? 18  ARG L HA   1 
ATOM   3450 H HB2  . ARG B 2 18  ? 44.45900 15.42000  33.17500  1.000 46.46614  ? 18  ARG L HB2  1 
ATOM   3451 H HB3  . ARG B 2 18  ? 43.12800 15.75200  32.37200  1.000 46.46614  ? 18  ARG L HB3  1 
ATOM   3452 H HG2  . ARG B 2 18  ? 42.17000 13.79700  33.27400  1.000 43.93443  ? 18  ARG L HG2  1 
ATOM   3453 H HG3  . ARG B 2 18  ? 43.46600 13.63100  34.17800  1.000 43.93443  ? 18  ARG L HG3  1 
ATOM   3454 H HD2  . ARG B 2 18  ? 43.03000 15.76200  35.11700  1.000 48.34973  ? 18  ARG L HD2  1 
ATOM   3455 H HD3  . ARG B 2 18  ? 41.67700 15.81700  34.28600  1.000 48.34973  ? 18  ARG L HD3  1 
ATOM   3456 H HE   . ARG B 2 18  ? 40.76400 14.46700  35.75400  1.000 55.18965  ? 18  ARG L HE   1 
ATOM   3457 H HH11 . ARG B 2 18  ? 44.01100 14.50600  36.45000  1.000 53.84306  ? 18  ARG L HH11 1 
ATOM   3458 H HH12 . ARG B 2 18  ? 43.88600 13.83800  37.77600  1.000 53.84306  ? 18  ARG L HH12 1 
ATOM   3459 H HH21 . ARG B 2 18  ? 40.61100 13.49600  37.77200  1.000 57.38514  ? 18  ARG L HH21 1 
ATOM   3460 H HH22 . ARG B 2 18  ? 41.83900 13.22900  38.57300  1.000 57.38514  ? 18  ARG L HH22 1 
ATOM   3461 N N    . VAL B 2 19  ? 43.06800 12.21500  30.84900  1.000 33.69919  ? 19  VAL L N    1 
ATOM   3462 C CA   . VAL B 2 19  ? 42.11600 11.40500  30.09800  1.000 31.90778  ? 19  VAL L CA   1 
ATOM   3463 C C    . VAL B 2 19  ? 41.24500 10.62600  31.07000  1.000 29.96754  ? 19  VAL L C    1 
ATOM   3464 O O    . VAL B 2 19  ? 41.74600 10.02900  32.02900  1.000 27.15549  ? 19  VAL L O    1 
ATOM   3465 C CB   . VAL B 2 19  ? 42.82600 10.44000  29.12600  1.000 30.12759  ? 19  VAL L CB   1 
ATOM   3466 C CG1  . VAL B 2 19  ? 41.82600 9.46200   28.53400  1.000 30.03811  ? 19  VAL L CG1  1 
ATOM   3467 C CG2  . VAL B 2 19  ? 43.52400 11.21300  28.02500  1.000 32.64817  ? 19  VAL L CG2  1 
ATOM   3468 H H    . VAL B 2 19  ? 43.60800 11.75300  31.33300  1.000 40.44260  ? 19  VAL L H    1 
ATOM   3469 H HA   . VAL B 2 19  ? 41.54600 11.99900  29.58500  1.000 38.29290  ? 19  VAL L HA   1 
ATOM   3470 H HB   . VAL B 2 19  ? 43.49700 9.93800   29.61400  1.000 36.15668  ? 19  VAL L HB   1 
ATOM   3471 H HG11 . VAL B 2 19  ? 42.22600 9.03000   27.76300  1.000 36.04930  ? 19  VAL L HG11 1 
ATOM   3472 H HG12 . VAL B 2 19  ? 41.59900 8.79900   29.20500  1.000 36.04930  ? 19  VAL L HG12 1 
ATOM   3473 H HG13 . VAL B 2 19  ? 41.03000 9.94700   28.26600  1.000 36.04930  ? 19  VAL L HG13 1 
ATOM   3474 H HG21 . VAL B 2 19  ? 43.93400 10.58600  27.40900  1.000 39.18137  ? 19  VAL L HG21 1 
ATOM   3475 H HG22 . VAL B 2 19  ? 42.87000 11.75600  27.55700  1.000 39.18137  ? 19  VAL L HG22 1 
ATOM   3476 H HG23 . VAL B 2 19  ? 44.20400 11.78100  28.42000  1.000 39.18137  ? 19  VAL L HG23 1 
ATOM   3477 N N    . THR B 2 20  ? 39.94200 10.60200  30.79500  1.000 32.86764  ? 20  THR L N    1 
ATOM   3478 C CA   . THR B 2 20  ? 38.97200 9.90800   31.63000  1.000 31.69861  ? 20  THR L CA   1 
ATOM   3479 C C    . THR B 2 20  ? 38.13000 8.97400   30.77500  1.000 28.85824  ? 20  THR L C    1 
ATOM   3480 O O    . THR B 2 20  ? 37.56300 9.39400   29.76200  1.000 28.50758  ? 20  THR L O    1 
ATOM   3481 C CB   . THR B 2 20  ? 38.07300 10.91000  32.36200  1.000 34.42929  ? 20  THR L CB   1 
ATOM   3482 O OG1  . THR B 2 20  ? 38.86800 11.69300  33.26100  1.000 35.95910  ? 20  THR L OG1  1 
ATOM   3483 C CG2  . THR B 2 20  ? 36.98100 10.19000  33.13500  1.000 36.94871  ? 20  THR L CG2  1 
ATOM   3484 H H    . THR B 2 20  ? 39.59000 10.99100  30.11300  1.000 39.44473  ? 20  THR L H    1 
ATOM   3485 H HA   . THR B 2 20  ? 39.43900 9.36700   32.28600  1.000 38.04191  ? 20  THR L HA   1 
ATOM   3486 H HB   . THR B 2 20  ? 37.64400 11.49500  31.71700  1.000 41.31872  ? 20  THR L HB   1 
ATOM   3487 H HG1  . THR B 2 20  ? 38.38100 12.23500  33.67800  1.000 43.15449  ? 20  THR L HG1  1 
ATOM   3488 H HG21 . THR B 2 20  ? 36.51300 10.81600  33.70900  1.000 44.34203  ? 20  THR L HG21 1 
ATOM   3489 H HG22 . THR B 2 20  ? 36.34700 9.79100   32.52000  1.000 44.34203  ? 20  THR L HG22 1 
ATOM   3490 H HG23 . THR B 2 20  ? 37.37000 9.49000   33.68400  1.000 44.34203  ? 20  THR L HG23 1 
ATOM   3491 N N    . ILE B 2 21  ? 38.04000 7.71600   31.19500  1.000 26.91764  ? 21  ILE L N    1 
ATOM   3492 C CA   . ILE B 2 21  ? 37.24500 6.70400   30.51200  1.000 26.29812  ? 21  ILE L CA   1 
ATOM   3493 C C    . ILE B 2 21  ? 36.29500 6.09100   31.52700  1.000 26.55828  ? 21  ILE L C    1 
ATOM   3494 O O    . ILE B 2 21  ? 36.73400 5.60000   32.57200  1.000 23.62629  ? 21  ILE L O    1 
ATOM   3495 C CB   . ILE B 2 21  ? 38.13200 5.61600   29.87700  1.000 24.76836  ? 21  ILE L CB   1 
ATOM   3496 C CG1  . ILE B 2 21  ? 39.05800 6.23400   28.82900  1.000 23.54731  ? 21  ILE L CG1  1 
ATOM   3497 C CG2  . ILE B 2 21  ? 37.27000 4.53200   29.26400  1.000 22.78759  ? 21  ILE L CG2  1 
ATOM   3498 C CD1  . ILE B 2 21  ? 40.14700 5.29400   28.34400  1.000 24.23858  ? 21  ILE L CD1  1 
ATOM   3499 H H    . ILE B 2 21  ? 38.44200 7.41700   31.89400  1.000 32.30473  ? 21  ILE L H    1 
ATOM   3500 H HA   . ILE B 2 21  ? 36.72300 7.12000   29.80900  1.000 31.56132  ? 21  ILE L HA   1 
ATOM   3501 H HB   . ILE B 2 21  ? 38.68000 5.21700   30.57000  1.000 29.72561  ? 21  ILE L HB   1 
ATOM   3502 H HG12 . ILE B 2 21  ? 38.52800 6.49400   28.05900  1.000 28.26034  ? 21  ILE L HG12 1 
ATOM   3503 H HG13 . ILE B 2 21  ? 39.48900 7.01300   29.21400  1.000 28.26034  ? 21  ILE L HG13 1 
ATOM   3504 H HG21 . ILE B 2 21  ? 37.84000 3.90100   28.79800  1.000 27.34868  ? 21  ILE L HG21 1 
ATOM   3505 H HG22 . ILE B 2 21  ? 36.78200 4.07900   29.96900  1.000 27.34868  ? 21  ILE L HG22 1 
ATOM   3506 H HG23 . ILE B 2 21  ? 36.64800 4.93800   28.64000  1.000 27.34868  ? 21  ILE L HG23 1 
ATOM   3507 H HD11 . ILE B 2 21  ? 40.71200 5.76600   27.71100  1.000 29.08987  ? 21  ILE L HD11 1 
ATOM   3508 H HD12 . ILE B 2 21  ? 40.67400 5.00200   29.10400  1.000 29.08987  ? 21  ILE L HD12 1 
ATOM   3509 H HD13 . ILE B 2 21  ? 39.73600 4.52900   27.91300  1.000 29.08987  ? 21  ILE L HD13 1 
ATOM   3510 N N    . THR B 2 22  ? 35.00300 6.10300   31.21800  1.000 28.33892  ? 22  THR L N    1 
ATOM   3511 C CA   . THR B 2 22  ? 33.99300 5.56200   32.11500  1.000 27.30834  ? 22  THR L CA   1 
ATOM   3512 C C    . THR B 2 22  ? 33.48700 4.21400   31.61200  1.000 27.37847  ? 22  THR L C    1 
ATOM   3513 O O    . THR B 2 22  ? 33.56100 3.89600   30.42300  1.000 25.85693  ? 22  THR L O    1 
ATOM   3514 C CB   . THR B 2 22  ? 32.82100 6.53500   32.26800  1.000 28.11867  ? 22  THR L CB   1 
ATOM   3515 O OG1  . THR B 2 22  ? 32.15800 6.69400   31.01000  1.000 30.79877  ? 22  THR L OG1  1 
ATOM   3516 C CG2  . THR B 2 22  ? 33.31100 7.88800   32.75100  1.000 29.74932  ? 22  THR L CG2  1 
ATOM   3517 H H    . THR B 2 22  ? 34.68500 6.42300   30.48600  1.000 34.01028  ? 22  THR L H    1 
ATOM   3518 H HA   . THR B 2 22  ? 34.39100 5.42800   32.99000  1.000 32.77357  ? 22  THR L HA   1 
ATOM   3519 H HB   . THR B 2 22  ? 32.19400 6.18300   32.92000  1.000 33.74598  ? 22  THR L HB   1 
ATOM   3520 H HG1  . THR B 2 22  ? 31.54700 7.26700   31.07700  1.000 36.96210  ? 22  THR L HG1  1 
ATOM   3521 H HG21 . THR B 2 22  ? 32.56000 8.49100   32.86700  1.000 35.70275  ? 22  THR L HG21 1 
ATOM   3522 H HG22 . THR B 2 22  ? 33.77100 7.79100   33.59900  1.000 35.70275  ? 22  THR L HG22 1 
ATOM   3523 H HG23 . THR B 2 22  ? 33.92300 8.27000   32.10200  1.000 35.70275  ? 22  THR L HG23 1 
ATOM   3524 N N    . CYS B 2 23  ? 32.95700 3.42600   32.54600  1.000 25.79733  ? 23  CYS L N    1 
ATOM   3525 C CA   . CYS B 2 23  ? 32.51400 2.06200   32.26200  1.000 24.72567  ? 23  CYS L CA   1 
ATOM   3526 C C    . CYS B 2 23  ? 31.31900 1.77100   33.15900  1.000 29.20889  ? 23  CYS L C    1 
ATOM   3527 O O    . CYS B 2 23  ? 31.46300 1.72500   34.38400  1.000 26.98682  ? 23  CYS L O    1 
ATOM   3528 C CB   . CYS B 2 23  ? 33.64900 1.06900   32.50300  1.000 26.67715  ? 23  CYS L CB   1 
ATOM   3529 S SG   . CYS B 2 23  ? 33.20600 -0.68200  32.45900  1.000 36.11065  ? 23  CYS L SG   1 
ATOM   3530 H H    . CYS B 2 23  ? 32.84200 3.66100   33.36500  1.000 30.96036  ? 23  CYS L H    1 
ATOM   3531 H HA   . CYS B 2 23  ? 32.22800 1.98700   31.33800  1.000 29.67437  ? 23  CYS L HA   1 
ATOM   3532 H HB2  . CYS B 2 23  ? 34.32300 1.21000   31.82000  1.000 32.01615  ? 23  CYS L HB2  1 
ATOM   3533 H HB3  . CYS B 2 23  ? 34.02400 1.24700   33.38000  1.000 32.01615  ? 23  CYS L HB3  1 
ATOM   3534 N N    . ARG B 2 24  ? 30.14600 1.58400   32.55700  1.000 27.34654  ? 24  ARG L N    1 
ATOM   3535 C CA   . ARG B 2 24  ? 28.91600 1.32100   33.29500  1.000 29.93760  ? 24  ARG L CA   1 
ATOM   3536 C C    . ARG B 2 24  ? 28.51000 -0.13500  33.10600  1.000 29.84882  ? 24  ARG L C    1 
ATOM   3537 O O    . ARG B 2 24  ? 28.29500 -0.58300  31.97400  1.000 27.78736  ? 24  ARG L O    1 
ATOM   3538 C CB   . ARG B 2 24  ? 27.78500 2.24700   32.84400  1.000 35.57880  ? 24  ARG L CB   1 
ATOM   3539 C CG   . ARG B 2 24  ? 26.43000 1.85600   33.42700  1.000 42.83882  ? 24  ARG L CG   1 
ATOM   3540 C CD   . ARG B 2 24  ? 25.43700 3.01300   33.45000  1.000 50.92788  ? 24  ARG L CD   1 
ATOM   3541 N NE   . ARG B 2 24  ? 25.86800 4.09000   34.33400  1.000 61.92744  ? 24  ARG L NE   1 
ATOM   3542 C CZ   . ARG B 2 24  ? 26.01600 5.36000   33.97200  1.000 70.44795  ? 24  ARG L CZ   1 
ATOM   3543 N NH1  . ARG B 2 24  ? 25.73100 5.77200   32.74700  1.000 76.29787  ? 24  ARG L NH1  1 
ATOM   3544 N NH2  . ARG B 2 24  ? 26.45100 6.24100   34.86800  1.000 63.12821  ? 24  ARG L NH2  1 
ATOM   3545 H H    . ARG B 2 24  ? 30.03700 1.60600   31.70400  1.000 32.81942  ? 24  ARG L H    1 
ATOM   3546 H HA   . ARG B 2 24  ? 29.08300 1.47300   34.23800  1.000 35.92869  ? 24  ARG L HA   1 
ATOM   3547 H HB2  . ARG B 2 24  ? 27.98500 3.15200   33.13100  1.000 42.69813  ? 24  ARG L HB2  1 
ATOM   3548 H HB3  . ARG B 2 24  ? 27.71600 2.21300   31.87700  1.000 42.69813  ? 24  ARG L HB3  1 
ATOM   3549 H HG2  . ARG B 2 24  ? 26.04800 1.14500   32.89000  1.000 51.41016  ? 24  ARG L HG2  1 
ATOM   3550 H HG3  . ARG B 2 24  ? 26.55500 1.55200   34.34000  1.000 51.41016  ? 24  ARG L HG3  1 
ATOM   3551 H HD2  . ARG B 2 24  ? 25.34800 3.37500   32.55400  1.000 61.11702  ? 24  ARG L HD2  1 
ATOM   3552 H HD3  . ARG B 2 24  ? 24.57800 2.69000   33.76300  1.000 61.11702  ? 24  ARG L HD3  1 
ATOM   3553 H HE   . ARG B 2 24  ? 26.04000 3.88800   35.15200  1.000 74.31650  ? 24  ARG L HE   1 
ATOM   3554 H HH11 . ARG B 2 24  ? 25.44200 5.21200   32.16100  1.000 91.56101  ? 24  ARG L HH11 1 
ATOM   3555 H HH12 . ARG B 2 24  ? 25.83500 6.59900   32.53600  1.000 91.56101  ? 24  ARG L HH12 1 
ATOM   3556 H HH21 . ARG B 2 24  ? 26.63200 5.98600   35.66900  1.000 75.75742  ? 24  ARG L HH21 1 
ATOM   3557 H HH22 . ARG B 2 24  ? 26.55100 7.06600   34.64700  1.000 75.75742  ? 24  ARG L HH22 1 
ATOM   3558 N N    . ALA B 2 25  ? 28.39500 -0.86200  34.21300  1.000 26.41656  ? 25  ALA L N    1 
ATOM   3559 C CA   . ALA B 2 25  ? 27.97900 -2.25600  34.18900  1.000 26.90727  ? 25  ALA L CA   1 
ATOM   3560 C C    . ALA B 2 25  ? 26.46200 -2.34800  34.28900  1.000 27.14788  ? 25  ALA L C    1 
ATOM   3561 O O    . ALA B 2 25  ? 25.82300 -1.54900  34.97700  1.000 28.68843  ? 25  ALA L O    1 
ATOM   3562 C CB   . ALA B 2 25  ? 28.63500 -3.02700  35.33600  1.000 24.85638  ? 25  ALA L CB   1 
ATOM   3563 H H    . ALA B 2 25  ? 28.55600 -0.56300  35.00300  1.000 31.70344  ? 25  ALA L H    1 
ATOM   3564 H HA   . ALA B 2 25  ? 28.25300 -2.66800  33.35500  1.000 32.29230  ? 25  ALA L HA   1 
ATOM   3565 H HB1  . ALA B 2 25  ? 28.33400 -3.94800  35.31000  1.000 29.83123  ? 25  ALA L HB1  1 
ATOM   3566 H HB2  . ALA B 2 25  ? 29.59800 -2.99100  35.23000  1.000 29.83123  ? 25  ALA L HB2  1 
ATOM   3567 H HB3  . ALA B 2 25  ? 28.37900 -2.61800  36.17800  1.000 29.83123  ? 25  ALA L HB3  1 
ATOM   3568 N N    . SER B 2 26  ? 25.88400 -3.32900  33.59100  1.000 24.57669  ? 26  SER L N    1 
ATOM   3569 C CA   . SER B 2 26  ? 24.43300 -3.48000  33.61200  1.000 25.86749  ? 26  SER L CA   1 
ATOM   3570 C C    . SER B 2 26  ? 23.92400 -4.03200  34.94000  1.000 26.04793  ? 26  SER L C    1 
ATOM   3571 O O    . SER B 2 26  ? 22.72700 -3.92000  35.22100  1.000 25.16687  ? 26  SER L O    1 
ATOM   3572 C CB   . SER B 2 26  ? 23.97800 -4.37800  32.45900  1.000 29.33828  ? 26  SER L CB   1 
ATOM   3573 O OG   . SER B 2 26  ? 24.55500 -5.66900  32.54100  1.000 30.82739  ? 26  SER L OG   1 
ATOM   3574 H H    . SER B 2 26  ? 26.30200 -3.90500  33.10900  1.000 29.49560  ? 26  SER L H    1 
ATOM   3575 H HA   . SER B 2 26  ? 24.03000 -2.60700  33.48300  1.000 31.04456  ? 26  SER L HA   1 
ATOM   3576 H HB2  . SER B 2 26  ? 23.01200 -4.46500  32.49200  1.000 35.20951  ? 26  SER L HB2  1 
ATOM   3577 H HB3  . SER B 2 26  ? 24.24500 -3.97000  31.62000  1.000 35.20951  ? 26  SER L HB3  1 
ATOM   3578 H HG   . SER B 2 26  ? 24.17800 -6.11400  33.14600  1.000 36.99644  ? 26  SER L HG   1 
ATOM   3579 N N    . GLN B 2 27  ? 24.79600 -4.61900  35.76000  1.000 26.51836  ? 27  GLN L N    1 
ATOM   3580 C CA   . GLN B 2 27  ? 24.42000 -5.06000  37.09900  1.000 27.17873  ? 27  GLN L CA   1 
ATOM   3581 C C    . GLN B 2 27  ? 25.66600 -5.07200  37.97700  1.000 25.31899  ? 27  GLN L C    1 
ATOM   3582 O O    . GLN B 2 27  ? 26.78700 -4.88500  37.50000  1.000 20.86550  ? 27  GLN L O    1 
ATOM   3583 C CB   . GLN B 2 27  ? 23.74500 -6.43500  37.06900  1.000 26.87827  ? 27  GLN L CB   1 
ATOM   3584 C CG   . GLN B 2 27  ? 24.66800 -7.58600  36.69400  1.000 31.26882  ? 27  GLN L CG   1 
ATOM   3585 C CD   . GLN B 2 27  ? 23.91500 -8.87900  36.44200  1.000 38.85905  ? 27  GLN L CD   1 
ATOM   3586 O OE1  . GLN B 2 27  ? 23.32800 -9.07300  35.37700  1.000 38.64766  ? 27  GLN L OE1  1 
ATOM   3587 N NE2  . GLN B 2 27  ? 23.92700 -9.77100  37.42500  1.000 41.94809  ? 27  GLN L NE2  1 
ATOM   3588 H H    . GLN B 2 27  ? 25.61800 -4.77400  35.56100  1.000 31.82560  ? 27  GLN L H    1 
ATOM   3589 H HA   . GLN B 2 27  ? 23.79000 -4.42800  37.48000  1.000 32.61805  ? 27  GLN L HA   1 
ATOM   3590 H HB2  . GLN B 2 27  ? 23.38700 -6.62300  37.95000  1.000 32.25749  ? 27  GLN L HB2  1 
ATOM   3591 H HB3  . GLN B 2 27  ? 23.02700 -6.41300  36.41700  1.000 32.25749  ? 27  GLN L HB3  1 
ATOM   3592 H HG2  . GLN B 2 27  ? 25.14900 -7.35500  35.88400  1.000 37.52615  ? 27  GLN L HG2  1 
ATOM   3593 H HG3  . GLN B 2 27  ? 25.29400 -7.73900  37.41900  1.000 37.52615  ? 27  GLN L HG3  1 
ATOM   3594 H HE21 . GLN B 2 27  ? 24.34700 -9.60100  38.15600  1.000 50.34128  ? 27  GLN L HE21 1 
ATOM   3595 H HE22 . GLN B 2 27  ? 23.51400 -10.52000 37.33100  1.000 50.34128  ? 27  GLN L HE22 1 
ATOM   3596 N N    . SER B 2 28  A 25.45700 -5.27900  39.27600  1.000 23.79825  ? 27  SER L N    1 
ATOM   3597 C CA   . SER B 2 28  A 26.56600 -5.23900  40.22300  1.000 21.92729  ? 27  SER L CA   1 
ATOM   3598 C C    . SER B 2 28  A 27.59500 -6.31900  39.90700  1.000 19.16453  ? 27  SER L C    1 
ATOM   3599 O O    . SER B 2 28  A 27.24700 -7.43900  39.52800  1.000 23.93781  ? 27  SER L O    1 
ATOM   3600 C CB   . SER B 2 28  A 26.05000 -5.42200  41.65300  1.000 20.22519  ? 27  SER L CB   1 
ATOM   3601 O OG   . SER B 2 28  A 24.96600 -4.55100  41.90200  1.000 23.43807  ? 27  SER L OG   1 
ATOM   3602 H H    . SER B 2 28  A 24.69100 -5.44400  39.63100  1.000 28.56147  ? 27  SER L H    1 
ATOM   3603 H HA   . SER B 2 28  A 27.00100 -4.37400  40.15800  1.000 26.31632  ? 27  SER L HA   1 
ATOM   3604 H HB2  . SER B 2 28  A 25.75400 -6.33800  41.76800  1.000 24.27380  ? 27  SER L HB2  1 
ATOM   3605 H HB3  . SER B 2 28  A 26.76600 -5.22300  42.27600  1.000 24.27380  ? 27  SER L HB3  1 
ATOM   3606 H HG   . SER B 2 28  A 24.91100 -4.38900  42.72500  1.000 28.12925  ? 27  SER L HG   1 
ATOM   3607 N N    . VAL B 2 29  B 28.87600 -5.96700  40.08100  1.000 21.51648  ? 27  VAL L N    1 
ATOM   3608 C CA   . VAL B 2 29  B 29.96700 -6.92300  39.90200  1.000 22.42685  ? 27  VAL L CA   1 
ATOM   3609 C C    . VAL B 2 29  B 30.13800 -7.74200  41.17900  1.000 25.05856  ? 27  VAL L C    1 
ATOM   3610 O O    . VAL B 2 29  B 29.64700 -7.38800  42.24700  1.000 24.67784  ? 27  VAL L O    1 
ATOM   3611 C CB   . VAL B 2 29  B 31.27600 -6.19900  39.52900  1.000 21.84620  ? 27  VAL L CB   1 
ATOM   3612 C CG1  . VAL B 2 29  B 31.11800 -5.44000  38.21500  1.000 26.55924  ? 27  VAL L CG1  1 
ATOM   3613 C CG2  . VAL B 2 29  B 31.72500 -5.25400  40.65400  1.000 26.11889  ? 27  VAL L CG2  1 
ATOM   3614 H H    . VAL B 2 29  B 29.13600 -5.17800  40.30300  1.000 25.82335  ? 27  VAL L H    1 
ATOM   3615 H HA   . VAL B 2 29  B 29.74200 -7.53000  39.18000  1.000 26.91579  ? 27  VAL L HA   1 
ATOM   3616 H HB   . VAL B 2 29  B 31.97000 -6.86600  39.41100  1.000 26.21901  ? 27  VAL L HB   1 
ATOM   3617 H HG11 . VAL B 2 29  B 31.96000 -5.01100  37.99600  1.000 31.87466  ? 27  VAL L HG11 1 
ATOM   3618 H HG12 . VAL B 2 29  B 30.87500 -6.06700  37.51600  1.000 31.87466  ? 27  VAL L HG12 1 
ATOM   3619 H HG13 . VAL B 2 29  B 30.42300 -4.77200  38.31800  1.000 31.87466  ? 27  VAL L HG13 1 
ATOM   3620 H HG21 . VAL B 2 29  B 32.51700 -4.77400  40.36500  1.000 31.34624  ? 27  VAL L HG21 1 
ATOM   3621 H HG22 . VAL B 2 29  B 31.00900 -4.62700  40.84400  1.000 31.34624  ? 27  VAL L HG22 1 
ATOM   3622 H HG23 . VAL B 2 29  B 31.92500 -5.77800  41.44500  1.000 31.34624  ? 27  VAL L HG23 1 
ATOM   3623 N N    . TRP B 2 30  ? 30.87600 -8.85100  41.05700  1.000 22.10576  ? 28  TRP L N    1 
ATOM   3624 C CA   . TRP B 2 30  ? 31.10400 -9.74100  42.19400  1.000 27.59868  ? 28  TRP L CA   1 
ATOM   3625 C C    . TRP B 2 30  ? 31.69400 -8.98000  43.37600  1.000 26.47735  ? 28  TRP L C    1 
ATOM   3626 O O    . TRP B 2 30  ? 32.67800 -8.25200  43.23300  1.000 26.84743  ? 28  TRP L O    1 
ATOM   3627 C CB   . TRP B 2 30  ? 32.04200 -10.87600 41.77300  1.000 27.12765  ? 28  TRP L CB   1 
ATOM   3628 C CG   . TRP B 2 30  ? 32.27900 -11.92100 42.82500  1.000 31.40891  ? 28  TRP L CG   1 
ATOM   3629 C CD1  . TRP B 2 30  ? 33.46300 -12.21500 43.43600  1.000 32.05836  ? 28  TRP L CD1  1 
ATOM   3630 C CD2  . TRP B 2 30  ? 31.30800 -12.81500 43.38000  1.000 28.33572  ? 28  TRP L CD2  1 
ATOM   3631 N NE1  . TRP B 2 30  ? 33.29000 -13.23900 44.33500  1.000 33.75831  ? 28  TRP L NE1  1 
ATOM   3632 C CE2  . TRP B 2 30  ? 31.97500 -13.62400 44.32100  1.000 33.75910  ? 28  TRP L CE2  1 
ATOM   3633 C CE3  . TRP B 2 30  ? 29.94000 -13.01000 43.17300  1.000 30.31781  ? 28  TRP L CE3  1 
ATOM   3634 C CZ2  . TRP B 2 30  ? 31.31800 -14.60700 45.05800  1.000 32.47767  ? 28  TRP L CZ2  1 
ATOM   3635 C CZ3  . TRP B 2 30  ? 29.29100 -13.98900 43.90100  1.000 32.70900  ? 28  TRP L CZ3  1 
ATOM   3636 C CH2  . TRP B 2 30  ? 29.98000 -14.77400 44.83400  1.000 31.38741  ? 28  TRP L CH2  1 
ATOM   3637 H H    . TRP B 2 30  ? 31.25400 -9.10700  40.32800  1.000 26.53048  ? 28  TRP L H    1 
ATOM   3638 H HA   . TRP B 2 30  ? 30.25900 -10.12300 42.47800  1.000 33.12199  ? 28  TRP L HA   1 
ATOM   3639 H HB2  . TRP B 2 30  ? 31.65900 -11.32200 41.00100  1.000 32.55675  ? 28  TRP L HB2  1 
ATOM   3640 H HB3  . TRP B 2 30  ? 32.90300 -10.49400 41.54200  1.000 32.55675  ? 28  TRP L HB3  1 
ATOM   3641 H HD1  . TRP B 2 30  ? 34.27000 -11.78400 43.26900  1.000 38.47360  ? 28  TRP L HD1  1 
ATOM   3642 H HE1  . TRP B 2 30  ? 33.90600 -13.58300 44.82600  1.000 40.51354  ? 28  TRP L HE1  1 
ATOM   3643 H HE3  . TRP B 2 30  ? 29.47500 -12.49100 42.55700  1.000 36.38494  ? 28  TRP L HE3  1 
ATOM   3644 H HZ2  . TRP B 2 30  ? 31.77300 -15.13000 45.67900  1.000 38.97677  ? 28  TRP L HZ2  1 
ATOM   3645 H HZ3  . TRP B 2 30  ? 28.38100 -14.12900 43.76900  1.000 39.25437  ? 28  TRP L HZ3  1 
ATOM   3646 H HH2  . TRP B 2 30  ? 29.51600 -15.42300 45.31300  1.000 37.66846  ? 28  TRP L HH2  1 
ATOM   3647 N N    . ARG B 2 31  ? 31.08000 -9.15000  44.54800  1.000 30.23950  ? 29  ARG L N    1 
ATOM   3648 C CA   . ARG B 2 31  ? 31.53900 -8.51100  45.78300  1.000 28.86829  ? 29  ARG L CA   1 
ATOM   3649 C C    . ARG B 2 31  ? 31.69200 -7.00100  45.63200  1.000 29.03872  ? 29  ARG L C    1 
ATOM   3650 O O    . ARG B 2 31  ? 32.42800 -6.37000  46.39700  1.000 29.28809  ? 29  ARG L O    1 
ATOM   3651 C CB   . ARG B 2 31  ? 32.86900 -9.11300  46.25900  1.000 30.14765  ? 29  ARG L CB   1 
ATOM   3652 C CG   . ARG B 2 31  ? 32.82500 -10.60700 46.51400  1.000 34.89836  ? 29  ARG L CG   1 
ATOM   3653 C CD   . ARG B 2 31  ? 34.22100 -11.18100 46.72400  1.000 43.14903  ? 29  ARG L CD   1 
ATOM   3654 N NE   . ARG B 2 31  ? 34.51400 -11.44400 48.12900  1.000 52.09773  ? 29  ARG L NE   1 
ATOM   3655 C CZ   . ARG B 2 31  ? 35.10900 -10.58900 48.95200  1.000 52.80775  ? 29  ARG L CZ   1 
ATOM   3656 N NH1  . ARG B 2 31  ? 35.47100 -9.38000  48.55400  1.000 58.09821  ? 29  ARG L NH1  1 
ATOM   3657 N NH2  . ARG B 2 31  ? 35.34900 -10.95800 50.20700  1.000 57.26847  ? 29  ARG L NH2  1 
ATOM   3658 H H    . ARG B 2 31  ? 30.38100 -9.64000  44.65500  1.000 36.29097  ? 29  ARG L H    1 
ATOM   3659 H HA   . ARG B 2 31  ? 30.86500 -8.67400  46.46100  1.000 34.64552  ? 29  ARG L HA   1 
ATOM   3660 H HB2  . ARG B 2 31  ? 33.54300 -8.95000  45.58100  1.000 36.18075  ? 29  ARG L HB2  1 
ATOM   3661 H HB3  . ARG B 2 31  ? 33.12300 -8.68100  47.09000  1.000 36.18075  ? 29  ARG L HB3  1 
ATOM   3662 H HG2  . ARG B 2 31  ? 32.30100 -10.78100 47.31100  1.000 41.88161  ? 29  ARG L HG2  1 
ATOM   3663 H HG3  . ARG B 2 31  ? 32.42500 -11.05100 45.75000  1.000 41.88161  ? 29  ARG L HG3  1 
ATOM   3664 H HD2  . ARG B 2 31  ? 34.29500 -12.01800 46.24000  1.000 51.78241  ? 29  ARG L HD2  1 
ATOM   3665 H HD3  . ARG B 2 31  ? 34.87700 -10.54800 46.39400  1.000 51.78241  ? 29  ARG L HD3  1 
ATOM   3666 H HE   . ARG B 2 31  ? 34.28500 -12.20900 48.44700  1.000 62.52085  ? 29  ARG L HE   1 
ATOM   3667 H HH11 . ARG B 2 31  ? 35.32300 -9.13200  47.74400  1.000 69.72142  ? 29  ARG L HH11 1 
ATOM   3668 H HH12 . ARG B 2 31  ? 35.85500 -8.84300  49.10500  1.000 69.72142  ? 29  ARG L HH12 1 
ATOM   3669 H HH21 . ARG B 2 31  ? 35.12000 -11.74300 50.47500  1.000 68.72573  ? 29  ARG L HH21 1 
ATOM   3670 H HH22 . ARG B 2 31  ? 35.73300 -10.41300 50.74900  1.000 68.72573  ? 29  ARG L HH22 1 
ATOM   3671 N N    . ASN B 2 32  ? 31.01400 -6.40000  44.65300  1.000 27.67801  ? 30  ASN L N    1 
ATOM   3672 C CA   . ASN B 2 32  ? 31.16200 -4.97000  44.37600  1.000 27.54755  ? 30  ASN L CA   1 
ATOM   3673 C C    . ASN B 2 32  ? 32.63500 -4.59400  44.23900  1.000 28.82806  ? 30  ASN L C    1 
ATOM   3674 O O    . ASN B 2 32  ? 33.03000 -3.45500  44.50100  1.000 29.89876  ? 30  ASN L O    1 
ATOM   3675 C CB   . ASN B 2 32  ? 30.48200 -4.12800  45.46200  1.000 27.76744  ? 30  ASN L CB   1 
ATOM   3676 C CG   . ASN B 2 32  ? 28.96900 -4.23900  45.42600  1.000 30.49807  ? 30  ASN L CG   1 
ATOM   3677 O OD1  . ASN B 2 32  ? 28.34300 -3.99000  44.39600  1.000 30.49843  ? 30  ASN L OD1  1 
ATOM   3678 N ND2  . ASN B 2 32  ? 28.37500 -4.62900  46.54800  1.000 32.56849  ? 30  ASN L ND2  1 
ATOM   3679 H H    . ASN B 2 32  ? 30.45900 -6.80100  44.13200  1.000 33.21719  ? 30  ASN L H    1 
ATOM   3680 H HA   . ASN B 2 32  ? 30.72700 -4.76900  43.53300  1.000 33.06063  ? 30  ASN L HA   1 
ATOM   3681 H HB2  . ASN B 2 32  ? 30.78500 -4.43000  46.33300  1.000 33.32450  ? 30  ASN L HB2  1 
ATOM   3682 H HB3  . ASN B 2 32  ? 30.71900 -3.19600  45.33400  1.000 33.32450  ? 30  ASN L HB3  1 
ATOM   3683 H HD21 . ASN B 2 32  ? 27.51900 -4.70700  46.57700  1.000 39.08576  ? 30  ASN L HD21 1 
ATOM   3684 H HD22 . ASN B 2 32  ? 28.84600 -4.80400  47.24500  1.000 39.08576  ? 30  ASN L HD22 1 
ATOM   3685 N N    . LYS B 2 33  ? 33.45500 -5.55800  43.80600  1.000 26.23647  ? 31  LYS L N    1 
ATOM   3686 C CA   . LYS B 2 33  ? 34.89700 -5.38200  43.80300  1.000 27.40671  ? 31  LYS L CA   1 
ATOM   3687 C C    . LYS B 2 33  ? 35.60000 -5.80100  42.51000  1.000 27.51783  ? 31  LYS L C    1 
ATOM   3688 O O    . LYS B 2 33  ? 36.61100 -5.20700  42.15300  1.000 24.54639  ? 31  LYS L O    1 
ATOM   3689 C CB   . LYS B 2 33  ? 35.50600 -6.16300  44.97500  1.000 31.82769  ? 31  LYS L CB   1 
ATOM   3690 C CG   . LYS B 2 33  ? 37.02400 -6.15200  45.05400  1.000 41.06832  ? 31  LYS L CG   1 
ATOM   3691 C CD   . LYS B 2 33  ? 37.50200 -6.95000  46.26700  1.000 47.77806  ? 31  LYS L CD   1 
ATOM   3692 C CE   . LYS B 2 33  ? 39.02200 -6.97300  46.36800  1.000 48.97880  ? 31  LYS L CE   1 
ATOM   3693 N NZ   . LYS B 2 33  ? 39.49500 -7.73500  47.55900  1.000 50.38868  ? 31  LYS L NZ   1 
ATOM   3694 H H    . LYS B 2 33  ? 33.19400 -6.32200  43.51000  1.000 31.48734  ? 31  LYS L H    1 
ATOM   3695 H HA   . LYS B 2 33  ? 35.05400 -4.42900  43.88900  1.000 32.89163  ? 31  LYS L HA   1 
ATOM   3696 H HB2  . LYS B 2 33  ? 35.17100 -5.78100  45.80100  1.000 38.19680  ? 31  LYS L HB2  1 
ATOM   3697 H HB3  . LYS B 2 33  ? 35.22700 -7.08900  44.90100  1.000 38.19680  ? 31  LYS L HB3  1 
ATOM   3698 H HG2  . LYS B 2 33  ? 37.39400 -6.55500  44.25300  1.000 49.28556  ? 31  LYS L HG2  1 
ATOM   3699 H HG3  . LYS B 2 33  ? 37.33900 -5.23900  45.14100  1.000 49.28556  ? 31  LYS L HG3  1 
ATOM   3700 H HD2  . LYS B 2 33  ? 37.15100 -6.54600  47.07500  1.000 57.33725  ? 31  LYS L HD2  1 
ATOM   3701 H HD3  . LYS B 2 33  ? 37.19000 -7.86600  46.19100  1.000 57.33725  ? 31  LYS L HD3  1 
ATOM   3702 H HE2  . LYS B 2 33  ? 39.38700 -7.39500  45.57400  1.000 58.77814  ? 31  LYS L HE2  1 
ATOM   3703 H HE3  . LYS B 2 33  ? 39.35000 -6.06300  46.44100  1.000 58.77814  ? 31  LYS L HE3  1 
ATOM   3704 H HZ1  . LYS B 2 33  ? 40.38400 -7.74300  47.58200  1.000 60.46999  ? 31  LYS L HZ1  1 
ATOM   3705 H HZ2  . LYS B 2 33  ? 39.19000 -7.35500  48.30400  1.000 60.46999  ? 31  LYS L HZ2  1 
ATOM   3706 H HZ3  . LYS B 2 33  ? 39.19900 -8.57300  47.52100  1.000 60.46999  ? 31  LYS L HZ3  1 
ATOM   3707 N N    . ASN B 2 34  ? 35.09700 -6.82300  41.81000  1.000 23.73552  ? 32  ASN L N    1 
ATOM   3708 C CA   . ASN B 2 34  ? 35.87800 -7.44200  40.73100  1.000 26.27856  ? 32  ASN L CA   1 
ATOM   3709 C C    . ASN B 2 34  ? 35.68800 -6.68900  39.41600  1.000 23.30692  ? 32  ASN L C    1 
ATOM   3710 O O    . ASN B 2 34  ? 34.92200 -7.08600  38.53500  1.000 23.75776  ? 32  ASN L O    1 
ATOM   3711 C CB   . ASN B 2 34  ? 35.49500 -8.91000  40.58000  1.000 24.41641  ? 32  ASN L CB   1 
ATOM   3712 C CG   . ASN B 2 34  ? 36.00300 -9.77100  41.71600  1.000 29.83982  ? 32  ASN L CG   1 
ATOM   3713 O OD1  . ASN B 2 34  ? 35.91000 -9.40400  42.89000  1.000 28.41703  ? 32  ASN L OD1  1 
ATOM   3714 N ND2  . ASN B 2 34  ? 36.55900 -10.92500 41.36900  1.000 28.55801  ? 32  ASN L ND2  1 
ATOM   3715 H H    . ASN B 2 34  ? 34.32100 -7.17000  41.93800  1.000 28.48619  ? 32  ASN L H    1 
ATOM   3716 H HA   . ASN B 2 34  ? 36.81400 -7.36500  40.97100  1.000 31.53785  ? 32  ASN L HA   1 
ATOM   3717 H HB2  . ASN B 2 34  ? 34.52800 -8.98300  40.55800  1.000 29.30326  ? 32  ASN L HB2  1 
ATOM   3718 H HB3  . ASN B 2 34  ? 35.87300 -9.25100  39.75400  1.000 29.30326  ? 32  ASN L HB3  1 
ATOM   3719 H HD21 . ASN B 2 34  ? 36.86500 -11.45400 41.97500  1.000 34.27318  ? 32  ASN L HD21 1 
ATOM   3720 H HD22 . ASN B 2 34  ? 36.61300 -11.14300 40.54000  1.000 34.27318  ? 32  ASN L HD22 1 
ATOM   3721 N N    . VAL B 2 35  ? 36.42400 -5.58600  39.27900  1.000 22.86634  ? 33  VAL L N    1 
ATOM   3722 C CA   . VAL B 2 35  ? 36.57100 -4.88500  38.00900  1.000 23.14717  ? 33  VAL L CA   1 
ATOM   3723 C C    . VAL B 2 35  ? 38.05400 -4.64400  37.77100  1.000 23.69839  ? 33  VAL L C    1 
ATOM   3724 O O    . VAL B 2 35  ? 38.78500 -4.25300  38.68800  1.000 21.98681  ? 33  VAL L O    1 
ATOM   3725 C CB   . VAL B 2 35  ? 35.80200 -3.54800  37.97300  1.000 25.53747  ? 33  VAL L CB   1 
ATOM   3726 C CG1  . VAL B 2 35  ? 36.21600 -2.72100  36.74300  1.000 24.87838  ? 33  VAL L CG1  1 
ATOM   3727 C CG2  . VAL B 2 35  ? 34.31600 -3.80500  37.95900  1.000 26.89847  ? 33  VAL L CG2  1 
ATOM   3728 H H    . VAL B 2 35  ? 36.85700 -5.21900  39.92500  1.000 27.44318  ? 33  VAL L H    1 
ATOM   3729 H HA   . VAL B 2 35  ? 36.21800 -5.44700  37.30200  1.000 27.78017  ? 33  VAL L HA   1 
ATOM   3730 H HB   . VAL B 2 35  ? 36.01900 -3.03600  38.76800  1.000 30.64854  ? 33  VAL L HB   1 
ATOM   3731 H HG11 . VAL B 2 35  ? 35.58100 -1.99800  36.62000  1.000 29.85763  ? 33  VAL L HG11 1 
ATOM   3732 H HG12 . VAL B 2 35  ? 37.10400 -2.36000  36.89100  1.000 29.85763  ? 33  VAL L HG12 1 
ATOM   3733 H HG13 . VAL B 2 35  ? 36.21800 -3.29600  35.96200  1.000 29.85763  ? 33  VAL L HG13 1 
ATOM   3734 H HG21 . VAL B 2 35  ? 33.84900 -2.95600  37.91300  1.000 32.28174  ? 33  VAL L HG21 1 
ATOM   3735 H HG22 . VAL B 2 35  ? 34.09600 -4.34600  37.18500  1.000 32.28174  ? 33  VAL L HG22 1 
ATOM   3736 H HG23 . VAL B 2 35  ? 34.06900 -4.27400  38.77100  1.000 32.28174  ? 33  VAL L HG23 1 
ATOM   3737 N N    . ALA B 2 36  ? 38.49500 -4.87900  36.54100  1.000 21.54738  ? 34  ALA L N    1 
ATOM   3738 C CA   . ALA B 2 36  ? 39.87500 -4.64600  36.15400  1.000 21.64809  ? 34  ALA L CA   1 
ATOM   3739 C C    . ALA B 2 36  ? 39.90100 -3.81700  34.88000  1.000 20.29791  ? 34  ALA L C    1 
ATOM   3740 O O    . ALA B 2 36  ? 38.91800 -3.74900  34.13700  1.000 18.24604  ? 34  ALA L O    1 
ATOM   3741 C CB   . ALA B 2 36  ? 40.63300 -5.95900  35.94400  1.000 19.89610  ? 34  ALA L CB   1 
ATOM   3742 H H    . ALA B 2 36  ? 38.00300 -5.17900  35.90300  1.000 25.86043  ? 34  ALA L H    1 
ATOM   3743 H HA   . ALA B 2 36  ? 40.32900 -4.14800  36.85200  1.000 25.98128  ? 34  ALA L HA   1 
ATOM   3744 H HB1  . ALA B 2 36  ? 41.52800 -5.76000  35.63000  1.000 23.87889  ? 34  ALA L HB1  1 
ATOM   3745 H HB2  . ALA B 2 36  ? 40.67700 -6.43600  36.78800  1.000 23.87889  ? 34  ALA L HB2  1 
ATOM   3746 H HB3  . ALA B 2 36  ? 40.16200 -6.49300  35.28600  1.000 23.87889  ? 34  ALA L HB3  1 
ATOM   3747 N N    . TRP B 2 37  ? 41.04000 -3.17200  34.64900  1.000 21.33809  ? 35  TRP L N    1 
ATOM   3748 C CA   . TRP B 2 37  ? 41.27200 -2.36900  33.45800  1.000 20.28799  ? 35  TRP L CA   1 
ATOM   3749 C C    . TRP B 2 37  ? 42.46100 -2.94200  32.70500  1.000 21.78929  ? 35  TRP L C    1 
ATOM   3750 O O    . TRP B 2 37  ? 43.50900 -3.21200  33.30300  1.000 21.89703  ? 35  TRP L O    1 
ATOM   3751 C CB   . TRP B 2 37  ? 41.52500 -0.90600  33.81900  1.000 19.96752  ? 35  TRP L CB   1 
ATOM   3752 C CG   . TRP B 2 37  ? 40.29700 -0.17300  34.24500  1.000 20.87804  ? 35  TRP L CG   1 
ATOM   3753 C CD1  . TRP B 2 37  ? 39.88000 0.06400   35.52500  1.000 20.11705  ? 35  TRP L CD1  1 
ATOM   3754 C CD2  . TRP B 2 37  ? 39.32300 0.43000   33.38800  1.000 20.44779  ? 35  TRP L CD2  1 
ATOM   3755 N NE1  . TRP B 2 37  ? 38.70500 0.77700   35.51500  1.000 20.62669  ? 35  TRP L NE1  1 
ATOM   3756 C CE2  . TRP B 2 37  ? 38.34400 1.01600   34.21500  1.000 23.33898  ? 35  TRP L CE2  1 
ATOM   3757 C CE3  . TRP B 2 37  ? 39.18600 0.53200   32.00100  1.000 20.43724  ? 35  TRP L CE3  1 
ATOM   3758 C CZ2  . TRP B 2 37  ? 37.24000 1.68800   33.69900  1.000 24.39832  ? 35  TRP L CZ2  1 
ATOM   3759 C CZ3  . TRP B 2 37  ? 38.09400 1.20100   31.49200  1.000 21.86857  ? 35  TRP L CZ3  1 
ATOM   3760 C CH2  . TRP B 2 37  ? 37.13400 1.77300   32.33800  1.000 22.62746  ? 35  TRP L CH2  1 
ATOM   3761 H H    . TRP B 2 37  ? 41.71200 -3.18600  35.18500  1.000 25.60928  ? 35  TRP L H    1 
ATOM   3762 H HA   . TRP B 2 37  ? 40.49300 -2.40400  32.88100  1.000 24.34916  ? 35  TRP L HA   1 
ATOM   3763 H HB2  . TRP B 2 37  ? 42.16100 -0.87000  34.55000  1.000 23.96459  ? 35  TRP L HB2  1 
ATOM   3764 H HB3  . TRP B 2 37  ? 41.88700 -0.45100  33.04200  1.000 23.96459  ? 35  TRP L HB3  1 
ATOM   3765 H HD1  . TRP B 2 37  ? 40.32700 -0.21700  36.29100  1.000 24.14403  ? 35  TRP L HD1  1 
ATOM   3766 H HE1  . TRP B 2 37  ? 38.26800 1.03100   36.21100  1.000 24.75560  ? 35  TRP L HE1  1 
ATOM   3767 H HE3  . TRP B 2 37  ? 39.81800 0.15500   31.43200  1.000 24.52826  ? 35  TRP L HE3  1 
ATOM   3768 H HZ2  . TRP B 2 37  ? 36.59900 2.06500   34.25800  1.000 29.28156  ? 35  TRP L HZ2  1 
ATOM   3769 H HZ3  . TRP B 2 37  ? 37.99200 1.27500   30.57100  1.000 26.24585  ? 35  TRP L HZ3  1 
ATOM   3770 H HH2  . TRP B 2 37  ? 36.40900 2.22000   31.96600  1.000 27.15652  ? 35  TRP L HH2  1 
ATOM   3771 N N    . TYR B 2 38  ? 42.28900 -3.12900  31.39700  1.000 20.55896  ? 36  TYR L N    1 
ATOM   3772 C CA   . TYR B 2 38  ? 43.30300 -3.70300  30.53000  1.000 19.94676  ? 36  TYR L CA   1 
ATOM   3773 C C    . TYR B 2 38  ? 43.70200 -2.70700  29.45100  1.000 20.73892  ? 36  TYR L C    1 
ATOM   3774 O O    . TYR B 2 38  ? 42.88400 -1.91200  28.98100  1.000 19.62870  ? 36  TYR L O    1 
ATOM   3775 C CB   . TYR B 2 38  ? 42.79900 -4.98300  29.86400  1.000 21.31853  ? 36  TYR L CB   1 
ATOM   3776 C CG   . TYR B 2 38  ? 42.97900 -6.22900  30.69300  1.000 21.99861  ? 36  TYR L CG   1 
ATOM   3777 C CD1  . TYR B 2 38  ? 42.09600 -6.54000  31.72100  1.000 21.95860  ? 36  TYR L CD1  1 
ATOM   3778 C CD2  . TYR B 2 38  ? 44.02800 -7.10200  30.44000  1.000 22.40754  ? 36  TYR L CD2  1 
ATOM   3779 C CE1  . TYR B 2 38  ? 42.25900 -7.68700  32.47700  1.000 21.38773  ? 36  TYR L CE1  1 
ATOM   3780 C CE2  . TYR B 2 38  ? 44.19800 -8.24700  31.18600  1.000 23.76907  ? 36  TYR L CE2  1 
ATOM   3781 C CZ   . TYR B 2 38  ? 43.31300 -8.53500  32.20500  1.000 24.52960  ? 36  TYR L CZ   1 
ATOM   3782 O OH   . TYR B 2 38  ? 43.48500 -9.68000  32.94600  1.000 22.07745  ? 36  TYR L OH   1 
ATOM   3783 H H    . TYR B 2 38  ? 41.56600 -2.92200  30.98000  1.000 24.67433  ? 36  TYR L H    1 
ATOM   3784 H HA   . TYR B 2 38  ? 44.08900 -3.91200  31.05900  1.000 23.93969  ? 36  TYR L HA   1 
ATOM   3785 H HB2  . TYR B 2 38  ? 41.85100 -4.88600  29.68300  1.000 25.58581  ? 36  TYR L HB2  1 
ATOM   3786 H HB3  . TYR B 2 38  ? 43.28400 -5.11100  29.03400  1.000 25.58581  ? 36  TYR L HB3  1 
ATOM   3787 H HD1  . TYR B 2 38  ? 41.38600 -5.96900  31.90300  1.000 26.35389  ? 36  TYR L HD1  1 
ATOM   3788 H HD2  . TYR B 2 38  ? 44.62600 -6.91100  29.75500  1.000 26.89261  ? 36  TYR L HD2  1 
ATOM   3789 H HE1  . TYR B 2 38  ? 41.66200 -7.88500  33.16200  1.000 25.66885  ? 36  TYR L HE1  1 
ATOM   3790 H HE2  . TYR B 2 38  ? 44.90500 -8.82300  31.00400  1.000 28.52645  ? 36  TYR L HE2  1 
ATOM   3791 H HH   . TYR B 2 38  ? 42.84500 -9.77400  33.48200  1.000 26.49651  ? 36  TYR L HH   1 
ATOM   3792 N N    . GLN B 2 39  ? 44.97200 -2.77100  29.06200  1.000 20.95726  ? 37  GLN L N    1 
ATOM   3793 C CA   . GLN B 2 39  ? 45.54900 -1.94400  28.01100  1.000 19.35714  ? 37  GLN L CA   1 
ATOM   3794 C C    . GLN B 2 39  ? 46.04200 -2.85900  26.90100  1.000 20.80809  ? 37  GLN L C    1 
ATOM   3795 O O    . GLN B 2 39  ? 46.78300 -3.81000  27.17000  1.000 22.22843  ? 37  GLN L O    1 
ATOM   3796 C CB   . GLN B 2 39  ? 46.70500 -1.11100  28.57000  1.000 20.59789  ? 37  GLN L CB   1 
ATOM   3797 C CG   . GLN B 2 39  ? 47.39900 -0.22100  27.57000  1.000 21.17779  ? 37  GLN L CG   1 
ATOM   3798 C CD   . GLN B 2 39  ? 48.72400 0.30100   28.08600  1.000 22.82731  ? 37  GLN L CD   1 
ATOM   3799 O OE1  . GLN B 2 39  ? 49.63200 -0.47000  28.39500  1.000 22.95674  ? 37  GLN L OE1  1 
ATOM   3800 N NE2  . GLN B 2 39  ? 48.84200 1.61700   28.18000  1.000 25.34835  ? 37  GLN L NE2  1 
ATOM   3801 H H    . GLN B 2 39  ? 45.54400 -3.31200  29.40800  1.000 25.15228  ? 37  GLN L H    1 
ATOM   3802 H HA   . GLN B 2 39  ? 44.88500 -1.34000  27.64300  1.000 23.23213  ? 37  GLN L HA   1 
ATOM   3803 H HB2  . GLN B 2 39  ? 46.35800 -0.54000  29.27400  1.000 24.72104  ? 37  GLN L HB2  1 
ATOM   3804 H HB3  . GLN B 2 39  ? 47.37100 -1.71600  28.93200  1.000 24.72104  ? 37  GLN L HB3  1 
ATOM   3805 H HG2  . GLN B 2 39  ? 47.56900 -0.72700  26.76000  1.000 25.41692  ? 37  GLN L HG2  1 
ATOM   3806 H HG3  . GLN B 2 39  ? 46.83000 0.54000   27.37300  1.000 25.41692  ? 37  GLN L HG3  1 
ATOM   3807 H HE21 . GLN B 2 39  ? 48.18700 2.12600   27.95300  1.000 30.42159  ? 37  GLN L HE21 1 
ATOM   3808 H HE22 . GLN B 2 39  ? 49.57500 1.96400   28.46800  1.000 30.42159  ? 37  GLN L HE22 1 
ATOM   3809 N N    . GLN B 2 40  ? 45.63800 -2.58300  25.66100  1.000 20.88848  ? 38  GLN L N    1 
ATOM   3810 C CA   . GLN B 2 40  ? 46.07200 -3.37600  24.51700  1.000 20.86708  ? 38  GLN L CA   1 
ATOM   3811 C C    . GLN B 2 40  ? 46.73300 -2.47000  23.49000  1.000 20.98781  ? 38  GLN L C    1 
ATOM   3812 O O    . GLN B 2 40  ? 46.08200 -1.58400  22.92400  1.000 18.86479  ? 38  GLN L O    1 
ATOM   3813 C CB   . GLN B 2 40  ? 44.91200 -4.13600  23.87300  1.000 20.70728  ? 38  GLN L CB   1 
ATOM   3814 C CG   . GLN B 2 40  ? 45.37900 -5.09600  22.78600  1.000 22.68770  ? 38  GLN L CG   1 
ATOM   3815 C CD   . GLN B 2 40  ? 44.27400 -5.99300  22.27400  1.000 24.98893  ? 38  GLN L CD   1 
ATOM   3816 O OE1  . GLN B 2 40  ? 43.13500 -5.56100  22.10600  1.000 24.52862  ? 38  GLN L OE1  1 
ATOM   3817 N NE2  . GLN B 2 40  ? 44.60600 -7.25500  22.02600  1.000 26.41942  ? 38  GLN L NE2  1 
ATOM   3818 H H    . GLN B 2 40  ? 45.10800 -1.93600  25.45900  1.000 25.06974  ? 38  GLN L H    1 
ATOM   3819 H HA   . GLN B 2 40  ? 46.72700 -4.02000  24.82900  1.000 25.04407  ? 38  GLN L HA   1 
ATOM   3820 H HB2  . GLN B 2 40  ? 44.45300 -4.65200  24.55500  1.000 24.85230  ? 38  GLN L HB2  1 
ATOM   3821 H HB3  . GLN B 2 40  ? 44.30000 -3.50000  23.47100  1.000 24.85230  ? 38  GLN L HB3  1 
ATOM   3822 H HG2  . GLN B 2 40  ? 45.71800 -4.58300  22.03600  1.000 27.22881  ? 38  GLN L HG2  1 
ATOM   3823 H HG3  . GLN B 2 40  ? 46.08000 -5.66200  23.14500  1.000 27.22881  ? 38  GLN L HG3  1 
ATOM   3824 H HE21 . GLN B 2 40  ? 45.41300 -7.52100  22.15800  1.000 31.70687  ? 38  GLN L HE21 1 
ATOM   3825 H HE22 . GLN B 2 40  ? 44.01400 -7.80600  21.73300  1.000 31.70687  ? 38  GLN L HE22 1 
ATOM   3826 N N    . LYS B 2 41  ? 48.01000 -2.71000  23.23900  1.000 22.95696  ? 39  LYS L N    1 
ATOM   3827 C CA   . LYS B 2 41  ? 48.79600 -1.94000  22.29300  1.000 24.88755  ? 39  LYS L CA   1 
ATOM   3828 C C    . LYS B 2 41  ? 48.88600 -2.66700  20.96000  1.000 28.08804  ? 39  LYS L C    1 
ATOM   3829 O O    . LYS B 2 41  ? 48.63700 -3.87400  20.87600  1.000 29.26833  ? 39  LYS L O    1 
ATOM   3830 C CB   . LYS B 2 41  ? 50.19500 -1.67800  22.86300  1.000 26.08689  ? 39  LYS L CB   1 
ATOM   3831 C CG   . LYS B 2 41  ? 50.16500 -0.82200  24.14000  1.000 31.14967  ? 39  LYS L CG   1 
ATOM   3832 C CD   . LYS B 2 41  ? 51.54800 -0.34700  24.58200  1.000 32.32719  ? 39  LYS L CD   1 
ATOM   3833 C CE   . LYS B 2 41  ? 51.48200 0.34500   25.94400  1.000 30.85818  ? 39  LYS L CE   1 
ATOM   3834 N NZ   . LYS B 2 41  ? 52.78800 0.93500   26.35600  1.000 31.38840  ? 39  LYS L NZ   1 
ATOM   3835 H H    . LYS B 2 41  ? 48.46000 -3.33700  23.61900  1.000 27.55193  ? 39  LYS L H    1 
ATOM   3836 H HA   . LYS B 2 41  ? 48.37900 -1.07900  22.13100  1.000 29.86863  ? 39  LYS L HA   1 
ATOM   3837 H HB2  . LYS B 2 41  ? 50.61100 -2.52700  23.08100  1.000 31.30784  ? 39  LYS L HB2  1 
ATOM   3838 H HB3  . LYS B 2 41  ? 50.72400 -1.21000  22.19900  1.000 31.30784  ? 39  LYS L HB3  1 
ATOM   3839 H HG2  . LYS B 2 41  ? 49.61900 -0.03600  23.97800  1.000 37.38317  ? 39  LYS L HG2  1 
ATOM   3840 H HG3  . LYS B 2 41  ? 49.78600 -1.34700  24.86200  1.000 37.38317  ? 39  LYS L HG3  1 
ATOM   3841 H HD2  . LYS B 2 41  ? 52.14400 -1.10900  24.65400  1.000 38.79620  ? 39  LYS L HD2  1 
ATOM   3842 H HD3  . LYS B 2 41  ? 51.89500 0.28600   23.93400  1.000 38.79620  ? 39  LYS L HD3  1 
ATOM   3843 H HE2  . LYS B 2 41  ? 50.82900 1.06100   25.90300  1.000 37.03338  ? 39  LYS L HE2  1 
ATOM   3844 H HE3  . LYS B 2 41  ? 51.22200 -0.30500  26.61600  1.000 37.03338  ? 39  LYS L HE3  1 
ATOM   3845 H HZ1  . LYS B 2 41  ? 52.84500 0.95900   27.24300  1.000 37.66965  ? 39  LYS L HZ1  1 
ATOM   3846 H HZ2  . LYS B 2 41  ? 53.45900 0.44400   26.03600  1.000 37.66965  ? 39  LYS L HZ2  1 
ATOM   3847 H HZ3  . LYS B 2 41  ? 52.86100 1.76400   26.03900  1.000 37.66965  ? 39  LYS L HZ3  1 
ATOM   3848 N N    . PRO B 2 42  ? 49.23200 -1.95100  19.88600  1.000 29.80818  ? 40  PRO L N    1 
ATOM   3849 C CA   . PRO B 2 42  ? 49.17400 -2.54600  18.54200  1.000 33.04896  ? 40  PRO L CA   1 
ATOM   3850 C C    . PRO B 2 42  ? 49.91500 -3.86500  18.40700  1.000 34.29872  ? 40  PRO L C    1 
ATOM   3851 O O    . PRO B 2 42  ? 51.12400 -3.94100  18.64600  1.000 33.40803  ? 40  PRO L O    1 
ATOM   3852 C CB   . PRO B 2 42  ? 49.81300 -1.46400  17.65700  1.000 36.79882  ? 40  PRO L CB   1 
ATOM   3853 C CG   . PRO B 2 42  ? 49.57000 -0.19000  18.39100  1.000 35.31813  ? 40  PRO L CG   1 
ATOM   3854 C CD   . PRO B 2 42  ? 49.64900 -0.53700  19.85300  1.000 31.46893  ? 40  PRO L CD   1 
ATOM   3855 H HA   . PRO B 2 42  ? 48.24600 -2.68500  18.29700  1.000 39.66232  ? 40  PRO L HA   1 
ATOM   3856 H HB2  . PRO B 2 42  ? 50.76300 -1.63500  17.55800  1.000 44.16215  ? 40  PRO L HB2  1 
ATOM   3857 H HB3  . PRO B 2 42  ? 49.38600 -1.45300  16.78600  1.000 44.16215  ? 40  PRO L HB3  1 
ATOM   3858 H HG2  . PRO B 2 42  ? 50.25200 0.45900   18.15400  1.000 42.38533  ? 40  PRO L HG2  1 
ATOM   3859 H HG3  . PRO B 2 42  ? 48.69200 0.15500   18.16600  1.000 42.38533  ? 40  PRO L HG3  1 
ATOM   3860 H HD2  . PRO B 2 42  ? 50.55500 -0.43600  20.18400  1.000 37.76628  ? 40  PRO L HD2  1 
ATOM   3861 H HD3  . PRO B 2 42  ? 49.04300 0.01400   20.37300  1.000 37.76628  ? 40  PRO L HD3  1 
ATOM   3862 N N    . GLY B 2 43  ? 49.18700 -4.90900  18.01000  1.000 34.26845  ? 41  GLY L N    1 
ATOM   3863 C CA   . GLY B 2 43  ? 49.78700 -6.20800  17.78400  1.000 33.05897  ? 41  GLY L CA   1 
ATOM   3864 C C    . GLY B 2 43  ? 50.16600 -6.97000  19.03100  1.000 35.76815  ? 41  GLY L C    1 
ATOM   3865 O O    . GLY B 2 43  ? 50.92100 -7.94200  18.94000  1.000 39.57836  ? 41  GLY L O    1 
ATOM   3866 H H    . GLY B 2 43  ? 48.34000 -4.88500  17.86600  1.000 41.12571  ? 41  GLY L H    1 
ATOM   3867 H HA2  . GLY B 2 43  ? 49.16000 -6.75400  17.28500  1.000 39.67434  ? 41  GLY L HA2  1 
ATOM   3868 H HA3  . GLY B 2 43  ? 50.59200 -6.08900  17.25600  1.000 39.67434  ? 41  GLY L HA3  1 
ATOM   3869 N N    . LYS B 2 44  ? 49.65800 -6.56900  20.19400  1.000 33.82775  ? 42  LYS L N    1 
ATOM   3870 C CA   . LYS B 2 44  ? 50.01700 -7.18600  21.46000  1.000 34.24850  ? 42  LYS L CA   1 
ATOM   3871 C C    . LYS B 2 44  ? 48.78400 -7.77200  22.13500  1.000 28.05710  ? 42  LYS L C    1 
ATOM   3872 O O    . LYS B 2 44  ? 47.64500 -7.40700  21.83100  1.000 27.86786  ? 42  LYS L O    1 
ATOM   3873 C CB   . LYS B 2 44  ? 50.68100 -6.16900  22.40300  1.000 35.39893  ? 42  LYS L CB   1 
ATOM   3874 C CG   . LYS B 2 44  ? 51.93900 -5.51600  21.85000  1.000 40.02910  ? 42  LYS L CG   1 
ATOM   3875 C CD   . LYS B 2 44  ? 53.11900 -6.47600  21.86400  1.000 48.89887  ? 42  LYS L CD   1 
ATOM   3876 C CE   . LYS B 2 44  ? 54.41100 -5.77300  21.47100  1.000 56.63807  ? 42  LYS L CE   1 
ATOM   3877 N NZ   . LYS B 2 44  ? 54.39600 -5.31500  20.05100  1.000 60.21837  ? 42  LYS L NZ   1 
ATOM   3878 H H    . LYS B 2 44  ? 49.09200 -5.92700  20.27300  1.000 40.59686  ? 42  LYS L H    1 
ATOM   3879 H HA   . LYS B 2 44  ? 50.64100 -7.91000  21.29200  1.000 41.10177  ? 42  LYS L HA   1 
ATOM   3880 H HB2  . LYS B 2 44  ? 50.04300 -5.46300  22.59200  1.000 42.48229  ? 42  LYS L HB2  1 
ATOM   3881 H HB3  . LYS B 2 44  ? 50.92500 -6.62400  23.22400  1.000 42.48229  ? 42  LYS L HB3  1 
ATOM   3882 H HG2  . LYS B 2 44  ? 51.78100 -5.24000  20.93300  1.000 48.03849  ? 42  LYS L HG2  1 
ATOM   3883 H HG3  . LYS B 2 44  ? 52.16600 -4.74500  22.39300  1.000 48.03849  ? 42  LYS L HG3  1 
ATOM   3884 H HD2  . LYS B 2 44  ? 53.22800 -6.83800  22.75700  1.000 58.68221  ? 42  LYS L HD2  1 
ATOM   3885 H HD3  . LYS B 2 44  ? 52.95700 -7.19300  21.23100  1.000 58.68221  ? 42  LYS L HD3  1 
ATOM   3886 H HE2  . LYS B 2 44  ? 54.53600 -4.99600  22.03800  1.000 67.96925  ? 42  LYS L HE2  1 
ATOM   3887 H HE3  . LYS B 2 44  ? 55.15400 -6.38800  21.58200  1.000 67.96925  ? 42  LYS L HE3  1 
ATOM   3888 H HZ1  . LYS B 2 44  ? 55.15100 -4.88400  19.86200  1.000 72.26561  ? 42  LYS L HZ1  1 
ATOM   3889 H HZ2  . LYS B 2 44  ? 54.31800 -6.01400  19.50600  1.000 72.26561  ? 42  LYS L HZ2  1 
ATOM   3890 H HZ3  . LYS B 2 44  ? 53.70900 -4.76500  19.91600  1.000 72.26561  ? 42  LYS L HZ3  1 
ATOM   3891 N N    . ALA B 2 45  ? 49.02300 -8.69200  23.05300  1.000 27.01681  ? 43  ALA L N    1 
ATOM   3892 C CA   . ALA B 2 45  ? 47.94200 -9.19300  23.88400  1.000 26.31824  ? 43  ALA L CA   1 
ATOM   3893 C C    . ALA B 2 45  ? 47.58500 -8.15500  24.94700  1.000 26.41871  ? 43  ALA L C    1 
ATOM   3894 O O    . ALA B 2 45  ? 48.41700 -7.32000  25.31000  1.000 25.99824  ? 43  ALA L O    1 
ATOM   3895 C CB   . ALA B 2 45  ? 48.34600 -10.50100 24.55200  1.000 27.08923  ? 43  ALA L CB   1 
ATOM   3896 H H    . ALA B 2 45  ? 49.79300 -9.04000  23.21400  1.000 32.42374  ? 43  ALA L H    1 
ATOM   3897 H HA   . ALA B 2 45  ? 47.15700 -9.36800  23.34200  1.000 31.58545  ? 43  ALA L HA   1 
ATOM   3898 H HB1  . ALA B 2 45  ? 47.62000 -10.80200 25.12100  1.000 32.51064  ? 43  ALA L HB1  1 
ATOM   3899 H HB2  . ALA B 2 45  ? 48.52500 -11.16400 23.86600  1.000 32.51064  ? 43  ALA L HB2  1 
ATOM   3900 H HB3  . ALA B 2 45  ? 49.14300 -10.35200 25.08400  1.000 32.51064  ? 43  ALA L HB3  1 
ATOM   3901 N N    . PRO B 2 46  ? 46.35200 -8.17700  25.45100  1.000 26.28949  ? 44  PRO L N    1 
ATOM   3902 C CA   . PRO B 2 46  ? 45.97700 -7.22100  26.50200  1.000 22.98716  ? 44  PRO L CA   1 
ATOM   3903 C C    . PRO B 2 46  ? 46.83500 -7.38600  27.74800  1.000 26.33985  ? 44  PRO L C    1 
ATOM   3904 O O    . PRO B 2 46  ? 47.19900 -8.49900  28.13300  1.000 25.13840  ? 44  PRO L O    1 
ATOM   3905 C CB   . PRO B 2 46  ? 44.50700 -7.56000  26.78400  1.000 23.88860  ? 44  PRO L CB   1 
ATOM   3906 C CG   . PRO B 2 46  ? 44.02900 -8.25300  25.55000  1.000 24.07842  ? 44  PRO L CG   1 
ATOM   3907 C CD   . PRO B 2 46  ? 45.21500 -9.01600  25.03400  1.000 24.49829  ? 44  PRO L CD   1 
ATOM   3908 H HA   . PRO B 2 46  ? 46.05200 -6.31100  26.17400  1.000 27.58816  ? 44  PRO L HA   1 
ATOM   3909 H HB2  . PRO B 2 46  ? 44.44500 -8.14200  27.55700  1.000 28.66989  ? 44  PRO L HB2  1 
ATOM   3910 H HB3  . PRO B 2 46  ? 44.00500 -6.74500  26.94100  1.000 28.66989  ? 44  PRO L HB3  1 
ATOM   3911 H HG2  . PRO B 2 46  ? 43.30200 -8.85600  25.77300  1.000 28.89767  ? 44  PRO L HG2  1 
ATOM   3912 H HG3  . PRO B 2 46  ? 43.73000 -7.59900  24.90000  1.000 28.89767  ? 44  PRO L HG3  1 
ATOM   3913 H HD2  . PRO B 2 46  ? 45.26500 -9.89500  25.44000  1.000 29.40152  ? 44  PRO L HD2  1 
ATOM   3914 H HD3  . PRO B 2 46  ? 45.18000 -9.09800  24.06800  1.000 29.40152  ? 44  PRO L HD3  1 
ATOM   3915 N N    . LYS B 2 47  ? 47.14000 -6.25800  28.38900  1.000 24.26745  ? 45  LYS L N    1 
ATOM   3916 C CA   . LYS B 2 47  ? 47.94200 -6.21000  29.60600  1.000 23.78688  ? 45  LYS L CA   1 
ATOM   3917 C C    . LYS B 2 47  ? 47.12500 -5.55400  30.71200  1.000 24.55827  ? 45  LYS L C    1 
ATOM   3918 O O    . LYS B 2 47  ? 46.59000 -4.45700  30.52100  1.000 22.51758  ? 45  LYS L O    1 
ATOM   3919 C CB   . LYS B 2 47  ? 49.24200 -5.43600  29.36200  1.000 28.66767  ? 45  LYS L CB   1 
ATOM   3920 C CG   . LYS B 2 47  ? 50.11100 -5.23100  30.59500  1.000 36.63876  ? 45  LYS L CG   1 
ATOM   3921 C CD   . LYS B 2 47  ? 51.24100 -4.24700  30.30500  1.000 40.24825  ? 45  LYS L CD   1 
ATOM   3922 C CE   . LYS B 2 47  ? 51.96000 -3.82900  31.58000  1.000 48.43890  ? 45  LYS L CE   1 
ATOM   3923 N NZ   . LYS B 2 47  ? 52.92700 -2.72000  31.33600  1.000 56.80810  ? 45  LYS L NZ   1 
ATOM   3924 H H    . LYS B 2 47  ? 46.88200 -5.48000  28.12600  1.000 29.12451  ? 45  LYS L H    1 
ATOM   3925 H HA   . LYS B 2 47  ? 48.17000 -7.10800  29.89300  1.000 28.54783  ? 45  LYS L HA   1 
ATOM   3926 H HB2  . LYS B 2 47  ? 49.77200 -5.92400  28.71100  1.000 34.40477  ? 45  LYS L HB2  1 
ATOM   3927 H HB3  . LYS B 2 47  ? 49.01700 -4.55900  29.01600  1.000 34.40477  ? 45  LYS L HB3  1 
ATOM   3928 H HG2  . LYS B 2 47  ? 49.57000 -4.87400  31.31700  1.000 43.97009  ? 45  LYS L HG2  1 
ATOM   3929 H HG3  . LYS B 2 47  ? 50.50200 -6.07800  30.86000  1.000 43.97009  ? 45  LYS L HG3  1 
ATOM   3930 H HD2  . LYS B 2 47  ? 51.88700 -4.66500  29.71500  1.000 48.30148  ? 45  LYS L HD2  1 
ATOM   3931 H HD3  . LYS B 2 47  ? 50.87500 -3.45200  29.88700  1.000 48.30148  ? 45  LYS L HD3  1 
ATOM   3932 H HE2  . LYS B 2 47  ? 51.30700 -3.52400  32.23000  1.000 58.13024  ? 45  LYS L HE2  1 
ATOM   3933 H HE3  . LYS B 2 47  ? 52.45100 -4.58700  31.93400  1.000 58.13024  ? 45  LYS L HE3  1 
ATOM   3934 H HZ1  . LYS B 2 47  ? 53.52600 -2.96700  30.72600  1.000 68.17329  ? 45  LYS L HZ1  1 
ATOM   3935 H HZ2  . LYS B 2 47  ? 52.49600 -1.99900  31.04200  1.000 68.17329  ? 45  LYS L HZ2  1 
ATOM   3936 H HZ3  . LYS B 2 47  ? 53.35200 -2.51500  32.09100  1.000 68.17329  ? 45  LYS L HZ3  1 
ATOM   3937 N N    . ARG B 2 48  ? 47.03000 -6.22300  31.86400  1.000 23.56698  ? 46  ARG L N    1 
ATOM   3938 C CA   . ARG B 2 48  ? 46.22300 -5.70200  32.96400  1.000 25.41983  ? 46  ARG L CA   1 
ATOM   3939 C C    . ARG B 2 48  ? 46.93400 -4.54000  33.64800  1.000 23.18722  ? 46  ARG L C    1 
ATOM   3940 O O    . ARG B 2 48  ? 48.11200 -4.64000  34.00300  1.000 27.36915  ? 46  ARG L O    1 
ATOM   3941 C CB   . ARG B 2 48  ? 45.93000 -6.80200  33.98800  1.000 24.06797  ? 46  ARG L CB   1 
ATOM   3942 C CG   . ARG B 2 48  ? 44.92700 -6.37200  35.05900  1.000 25.58922  ? 46  ARG L CG   1 
ATOM   3943 C CD   . ARG B 2 48  ? 44.73000 -7.43100  36.13000  1.000 24.73742  ? 46  ARG L CD   1 
ATOM   3944 N NE   . ARG B 2 48  ? 45.94400 -7.65700  36.90400  1.000 28.71782  ? 46  ARG L NE   1 
ATOM   3945 C CZ   . ARG B 2 48  ? 46.00300 -8.39500  38.00300  1.000 32.19848  ? 46  ARG L CZ   1 
ATOM   3946 N NH1  . ARG B 2 48  ? 44.92600 -8.98000  38.50300  1.000 26.20501  ? 46  ARG L NH1  1 
ATOM   3947 N NH2  . ARG B 2 48  ? 47.17300 -8.55600  38.61400  1.000 31.65738  ? 46  ARG L NH2  1 
ATOM   3948 H H    . ARG B 2 48  ? 47.41900 -6.97200  32.02900  1.000 28.28394  ? 46  ARG L H    1 
ATOM   3949 H HA   . ARG B 2 48  ? 45.38000 -5.38300  32.60500  1.000 30.50737  ? 46  ARG L HA   1 
ATOM   3950 H HB2  . ARG B 2 48  ? 45.56300 -7.57200  33.52600  1.000 28.88514  ? 46  ARG L HB2  1 
ATOM   3951 H HB3  . ARG B 2 48  ? 46.75700 -7.04600  34.43300  1.000 28.88514  ? 46  ARG L HB3  1 
ATOM   3952 H HG2  . ARG B 2 48  ? 45.24900 -5.56500  35.49000  1.000 30.71064  ? 46  ARG L HG2  1 
ATOM   3953 H HG3  . ARG B 2 48  ? 44.06800 -6.20500  34.64100  1.000 30.71064  ? 46  ARG L HG3  1 
ATOM   3954 H HD2  . ARG B 2 48  ? 44.03100 -7.14400  36.73900  1.000 29.68847  ? 46  ARG L HD2  1 
ATOM   3955 H HD3  . ARG B 2 48  ? 44.47900 -8.26800  35.70900  1.000 29.68847  ? 46  ARG L HD3  1 
ATOM   3956 H HE   . ARG B 2 48  ? 46.66900 -7.28600  36.63000  1.000 34.46495  ? 46  ARG L HE   1 
ATOM   3957 H HH11 . ARG B 2 48  ? 44.16500 -8.88400  38.11400  1.000 31.44959  ? 46  ARG L HH11 1 
ATOM   3958 H HH12 . ARG B 2 48  ? 44.98700 -9.45500  39.21700  1.000 31.44959  ? 46  ARG L HH12 1 
ATOM   3959 H HH21 . ARG B 2 48  ? 47.88000 -8.18300  38.29500  1.000 37.99242  ? 46  ARG L HH21 1 
ATOM   3960 H HH22 . ARG B 2 48  ? 47.22400 -9.03300  39.32800  1.000 37.99242  ? 46  ARG L HH22 1 
ATOM   3961 N N    . LEU B 2 49  ? 46.21600 -3.43400  33.84200  1.000 23.79797  ? 47  LEU L N    1 
ATOM   3962 C CA   . LEU B 2 49  ? 46.75400 -2.29100  34.56900  1.000 23.42768  ? 47  LEU L CA   1 
ATOM   3963 C C    . LEU B 2 49  ? 46.21200 -2.18300  35.98600  1.000 25.49831  ? 47  LEU L C    1 
ATOM   3964 O O    . LEU B 2 49  ? 46.97500 -1.91200  36.91700  1.000 27.55809  ? 47  LEU L O    1 
ATOM   3965 C CB   . LEU B 2 49  ? 46.44300 -0.98700  33.83200  1.000 22.90772  ? 47  LEU L CB   1 
ATOM   3966 C CG   . LEU B 2 49  ? 46.95900 -0.85600  32.40100  1.000 24.00904  ? 47  LEU L CG   1 
ATOM   3967 C CD1  . LEU B 2 49  ? 46.73900 0.55700   31.92100  1.000 24.48820  ? 47  LEU L CD1  1 
ATOM   3968 C CD2  . LEU B 2 49  ? 48.42400 -1.23500  32.29200  1.000 29.79990  ? 47  LEU L CD2  1 
ATOM   3969 H H    . LEU B 2 49  ? 45.41100 -3.32400  33.56000  1.000 28.56114  ? 47  LEU L H    1 
ATOM   3970 H HA   . LEU B 2 49  ? 47.71800 -2.38900  34.61300  1.000 28.11679  ? 47  LEU L HA   1 
ATOM   3971 H HB2  . LEU B 2 49  ? 45.47900 -0.88900  33.79400  1.000 27.49283  ? 47  LEU L HB2  1 
ATOM   3972 H HB3  . LEU B 2 49  ? 46.83200 -0.25800  34.34000  1.000 27.49283  ? 47  LEU L HB3  1 
ATOM   3973 H HG   . LEU B 2 49  ? 46.46900 -1.47000  31.83100  1.000 28.81442  ? 47  LEU L HG   1 
ATOM   3974 H HD11 . LEU B 2 49  ? 47.09600 0.64500   31.02300  1.000 29.38940  ? 47  LEU L HD11 1 
ATOM   3975 H HD12 . LEU B 2 49  ? 45.78700 0.74500   31.91900  1.000 29.38940  ? 47  LEU L HD12 1 
ATOM   3976 H HD13 . LEU B 2 49  ? 47.19600 1.16900   32.52000  1.000 29.38940  ? 47  LEU L HD13 1 
ATOM   3977 H HD21 . LEU B 2 49  ? 48.72900 -1.06000  31.38800  1.000 35.76344  ? 47  LEU L HD21 1 
ATOM   3978 H HD22 . LEU B 2 49  ? 48.93500 -0.70400  32.92200  1.000 35.76344  ? 47  LEU L HD22 1 
ATOM   3979 H HD23 . LEU B 2 49  ? 48.52200 -2.17800  32.49700  1.000 35.76344  ? 47  LEU L HD23 1 
ATOM   3980 N N    . ILE B 2 50  ? 44.91000 -2.38800  36.16500  1.000 24.09837  ? 48  ILE L N    1 
ATOM   3981 C CA   . ILE B 2 50  ? 44.23600 -2.20000  37.44100  1.000 25.51920  ? 48  ILE L CA   1 
ATOM   3982 C C    . ILE B 2 50  ? 43.44200 -3.45900  37.75200  1.000 24.75881  ? 48  ILE L C    1 
ATOM   3983 O O    . ILE B 2 50  ? 42.99200 -4.17300  36.85100  1.000 23.25733  ? 48  ILE L O    1 
ATOM   3984 C CB   . ILE B 2 50  ? 43.30400 -0.96700  37.41300  1.000 23.67811  ? 48  ILE L CB   1 
ATOM   3985 C CG1  . ILE B 2 50  ? 44.07700 0.29100   37.00700  1.000 27.06977  ? 48  ILE L CG1  1 
ATOM   3986 C CG2  . ILE B 2 50  ? 42.61500 -0.76900  38.75700  1.000 26.48902  ? 48  ILE L CG2  1 
ATOM   3987 C CD1  . ILE B 2 50  ? 44.99000 0.82900   38.07100  1.000 30.83011  ? 48  ILE L CD1  1 
ATOM   3988 H H    . ILE B 2 50  ? 44.37900 -2.64500  35.53800  1.000 28.92161  ? 48  ILE L H    1 
ATOM   3989 H HA   . ILE B 2 50  ? 44.89600 -2.07100  38.14100  1.000 30.62661  ? 48  ILE L HA   1 
ATOM   3990 H HB   . ILE B 2 50  ? 42.61800 -1.13000  36.74600  1.000 28.41730  ? 48  ILE L HB   1 
ATOM   3991 H HG12 . ILE B 2 50  ? 44.62200 0.08200   36.23200  1.000 32.48729  ? 48  ILE L HG12 1 
ATOM   3992 H HG13 . ILE B 2 50  ? 43.44000 0.98800   36.78700  1.000 32.48729  ? 48  ILE L HG13 1 
ATOM   3993 H HG21 . ILE B 2 50  ? 42.18600 0.10100   38.76700  1.000 31.79039  ? 48  ILE L HG21 1 
ATOM   3994 H HG22 . ILE B 2 50  ? 41.95200 -1.46600  38.87800  1.000 31.79039  ? 48  ILE L HG22 1 
ATOM   3995 H HG23 . ILE B 2 50  ? 43.27900 -0.81800  39.46200  1.000 31.79039  ? 48  ILE L HG23 1 
ATOM   3996 H HD11 . ILE B 2 50  ? 45.51000 1.55900   37.70000  1.000 36.99971  ? 48  ILE L HD11 1 
ATOM   3997 H HD12 . ILE B 2 50  ? 44.45500 1.14800   38.81400  1.000 36.99971  ? 48  ILE L HD12 1 
ATOM   3998 H HD13 . ILE B 2 50  ? 45.58100 0.12000   38.36900  1.000 36.99971  ? 48  ILE L HD13 1 
ATOM   3999 N N    . TYR B 2 51  ? 43.27700 -3.73400  39.04100  1.000 24.14683  ? 49  TYR L N    1 
ATOM   4000 C CA   . TYR B 2 51  ? 42.38600 -4.79100  39.48900  1.000 24.38642  ? 49  TYR L CA   1 
ATOM   4001 C C    . TYR B 2 51  ? 41.70200 -4.32400  40.76500  1.000 27.82933  ? 49  TYR L C    1 
ATOM   4002 O O    . TYR B 2 51  ? 42.13600 -3.37000  41.41500  1.000 25.03587  ? 49  TYR L O    1 
ATOM   4003 C CB   . TYR B 2 51  ? 43.13400 -6.11700  39.70200  1.000 27.72791  ? 49  TYR L CB   1 
ATOM   4004 C CG   . TYR B 2 51  ? 44.16200 -6.09100  40.80500  1.000 30.59753  ? 49  TYR L CG   1 
ATOM   4005 C CD1  . TYR B 2 51  ? 45.40500 -5.50500  40.60900  1.000 32.00805  ? 49  TYR L CD1  1 
ATOM   4006 C CD2  . TYR B 2 51  ? 43.89400 -6.66400  42.04100  1.000 34.04870  ? 49  TYR L CD2  1 
ATOM   4007 C CE1  . TYR B 2 51  ? 46.34800 -5.47800  41.61500  1.000 35.82801  ? 49  TYR L CE1  1 
ATOM   4008 C CE2  . TYR B 2 51  ? 44.83100 -6.64600  43.05300  1.000 34.17740  ? 49  TYR L CE2  1 
ATOM   4009 C CZ   . TYR B 2 51  ? 46.05700 -6.05200  42.83600  1.000 38.70820  ? 49  TYR L CZ   1 
ATOM   4010 O OH   . TYR B 2 51  ? 46.99600 -6.03100  43.84300  1.000 43.76906  ? 49  TYR L OH   1 
ATOM   4011 H H    . TYR B 2 51  ? 43.67500 -3.31700  39.67900  1.000 28.97976  ? 49  TYR L H    1 
ATOM   4012 H HA   . TYR B 2 51  ? 41.70000 -4.96100  38.82500  1.000 29.26728  ? 49  TYR L HA   1 
ATOM   4013 H HB2  . TYR B 2 51  ? 42.48600 -6.80400  39.92200  1.000 33.27706  ? 49  TYR L HB2  1 
ATOM   4014 H HB3  . TYR B 2 51  ? 43.59400 -6.34600  38.87900  1.000 33.27706  ? 49  TYR L HB3  1 
ATOM   4015 H HD1  . TYR B 2 51  ? 45.60500 -5.12300  39.78500  1.000 38.41323  ? 49  TYR L HD1  1 
ATOM   4016 H HD2  . TYR B 2 51  ? 43.06900 -7.06700  42.18900  1.000 40.86201  ? 49  TYR L HD2  1 
ATOM   4017 H HE1  . TYR B 2 51  ? 47.17400 -5.07700  41.47200  1.000 42.99719  ? 49  TYR L HE1  1 
ATOM   4018 H HE2  . TYR B 2 51  ? 44.63800 -7.03300  43.87700  1.000 41.01645  ? 49  TYR L HE2  1 
ATOM   4019 H HH   . TYR B 2 51  ? 46.70600 -6.44400  44.51500  1.000 52.52645  ? 49  TYR L HH   1 
ATOM   4020 N N    . ALA B 2 52  ? 40.59900 -4.98900  41.09700  1.000 24.90665  ? 50  ALA L N    1 
ATOM   4021 C CA   . ALA B 2 52  ? 39.81900 -4.64300  42.28200  1.000 29.24992  ? 50  ALA L CA   1 
ATOM   4022 C C    . ALA B 2 52  ? 39.43400 -3.16500  42.26900  1.000 29.59020  ? 50  ALA L C    1 
ATOM   4023 O O    . ALA B 2 52  ? 39.49200 -2.47200  43.28800  1.000 28.24817  ? 50  ALA L O    1 
ATOM   4024 C CB   . ALA B 2 52  ? 40.58700 -5.00100  43.55200  1.000 29.00750  ? 50  ALA L CB   1 
ATOM   4025 H H    . ALA B 2 52  ? 40.27900 -5.64900  40.64800  1.000 29.89155  ? 50  ALA L H    1 
ATOM   4026 H HA   . ALA B 2 52  ? 38.99500 -5.15500  42.27400  1.000 35.10347  ? 50  ALA L HA   1 
ATOM   4027 H HB1  . ALA B 2 52  ? 40.04800 -4.76500  44.32400  1.000 34.81258  ? 50  ALA L HB1  1 
ATOM   4028 H HB2  . ALA B 2 52  ? 40.76700 -5.95400  43.55400  1.000 34.81258  ? 50  ALA L HB2  1 
ATOM   4029 H HB3  . ALA B 2 52  ? 41.42100 -4.50700  43.56700  1.000 34.81258  ? 50  ALA L HB3  1 
ATOM   4030 N N    . ILE B 2 53  ? 39.05100 -2.68200  41.08800  1.000 25.49748  ? 51  ILE L N    1 
ATOM   4031 C CA   . ILE B 2 53  ? 38.58500 -1.31900  40.85700  1.000 25.59735  ? 51  ILE L CA   1 
ATOM   4032 C C    . ILE B 2 53  ? 39.73500 -0.31700  40.88400  1.000 28.11925  ? 51  ILE L C    1 
ATOM   4033 O O    . ILE B 2 53  ? 39.84100 0.53100   39.99100  1.000 23.73612  ? 51  ILE L O    1 
ATOM   4034 C CB   . ILE B 2 53  ? 37.49800 -0.90400  41.87000  1.000 25.34624  ? 51  ILE L CB   1 
ATOM   4035 C CG1  . ILE B 2 53  ? 36.31200 -1.86700  41.80100  1.000 29.12771  ? 51  ILE L CG1  1 
ATOM   4036 C CG2  . ILE B 2 53  ? 37.03100 0.52900   41.58800  1.000 30.54915  ? 51  ILE L CG2  1 
ATOM   4037 C CD1  . ILE B 2 53  ? 35.19100 -1.54900  42.77300  1.000 31.85963  ? 51  ILE L CD1  1 
ATOM   4038 H H    . ILE B 2 53  ? 39.05200 -3.15100  40.36700  1.000 30.60054  ? 51  ILE L H    1 
ATOM   4039 H HA   . ILE B 2 53  ? 38.21100 -1.30500  39.96300  1.000 30.72039  ? 51  ILE L HA   1 
ATOM   4040 H HB   . ILE B 2 53  ? 37.87800 -0.94300  42.76200  1.000 30.41906  ? 51  ILE L HB   1 
ATOM   4041 H HG12 . ILE B 2 53  ? 35.94000 -1.83700  40.90500  1.000 34.95682  ? 51  ILE L HG12 1 
ATOM   4042 H HG13 . ILE B 2 53  ? 36.62700 -2.76200  41.99900  1.000 34.95682  ? 51  ILE L HG13 1 
ATOM   4043 H HG21 . ILE B 2 53  ? 36.32900 0.76200   42.21600  1.000 36.66255  ? 51  ILE L HG21 1 
ATOM   4044 H HG22 . ILE B 2 53  ? 37.78300 1.13300   41.69400  1.000 36.66255  ? 51  ILE L HG22 1 
ATOM   4045 H HG23 . ILE B 2 53  ? 36.69300 0.57800   40.68000  1.000 36.66255  ? 51  ILE L HG23 1 
ATOM   4046 H HD11 . ILE B 2 53  ? 34.57100 -2.29500  42.79500  1.000 38.23512  ? 51  ILE L HD11 1 
ATOM   4047 H HD12 . ILE B 2 53  ? 35.57000 -1.40800  43.65500  1.000 38.23512  ? 51  ILE L HD12 1 
ATOM   4048 H HD13 . ILE B 2 53  ? 34.73400 -0.74700  42.47700  1.000 38.23512  ? 51  ILE L HD13 1 
ATOM   4049 N N    . ALA B 2 54  ? 40.59700 -0.39000  41.90700  1.000 28.16841  ? 52  ALA L N    1 
ATOM   4050 C CA   . ALA B 2 54  ? 41.55200 0.68900   42.13100  1.000 27.90786  ? 52  ALA L CA   1 
ATOM   4051 C C    . ALA B 2 54  ? 42.95100 0.22700   42.52000  1.000 28.49765  ? 52  ALA L C    1 
ATOM   4052 O O    . ALA B 2 54  ? 43.79200 1.07600   42.84600  1.000 29.91814  ? 52  ALA L O    1 
ATOM   4053 C CB   . ALA B 2 54  ? 41.02300 1.63900   43.21700  1.000 31.06906  ? 52  ALA L CB   1 
ATOM   4054 H H    . ALA B 2 54  ? 40.64400 -1.04000  42.46800  1.000 33.80566  ? 52  ALA L H    1 
ATOM   4055 H HA   . ALA B 2 54  ? 41.64400 1.17000   41.29400  1.000 33.49300  ? 52  ALA L HA   1 
ATOM   4056 H HB1  . ALA B 2 54  ? 41.66300 2.35500   43.35000  1.000 37.28644  ? 52  ALA L HB1  1 
ATOM   4057 H HB2  . ALA B 2 54  ? 40.17200 2.00500   42.92900  1.000 37.28644  ? 52  ALA L HB2  1 
ATOM   4058 H HB3  . ALA B 2 54  ? 40.90700 1.14200   44.04200  1.000 37.28644  ? 52  ALA L HB3  1 
ATOM   4059 N N    . SER B 2 55  ? 43.24000 -1.06800  42.49500  1.000 27.42698  ? 53  SER L N    1 
ATOM   4060 C CA   . SER B 2 55  ? 44.56200 -1.56000  42.85400  1.000 27.74652  ? 53  SER L CA   1 
ATOM   4061 C C    . SER B 2 55  ? 45.46600 -1.51000  41.62800  1.000 30.36892  ? 53  SER L C    1 
ATOM   4062 O O    . SER B 2 55  ? 45.21600 -2.20200  40.63500  1.000 27.80718  ? 53  SER L O    1 
ATOM   4063 C CB   . SER B 2 55  ? 44.48200 -2.97800  43.41600  1.000 30.86806  ? 53  SER L CB   1 
ATOM   4064 O OG   . SER B 2 55  ? 43.78000 -2.97500  44.64800  1.000 35.10879  ? 53  SER L OG   1 
ATOM   4065 H H    . SER B 2 55  ? 42.68300 -1.68500  42.27100  1.000 32.91595  ? 53  SER L H    1 
ATOM   4066 H HA   . SER B 2 55  ? 44.94300 -0.98900  43.53800  1.000 33.29940  ? 53  SER L HA   1 
ATOM   4067 H HB2  . SER B 2 55  ? 44.01300 -3.54600  42.78400  1.000 37.04525  ? 53  SER L HB2  1 
ATOM   4068 H HB3  . SER B 2 55  ? 45.38000 -3.31500  43.56200  1.000 37.04525  ? 53  SER L HB3  1 
ATOM   4069 H HG   . SER B 2 55  ? 43.78700 -3.74400  44.98500  1.000 42.13412  ? 53  SER L HG   1 
ATOM   4070 N N    . LEU B 2 56  ? 46.50000 -0.68200  41.70000  1.000 30.37765  ? 54  LEU L N    1 
ATOM   4071 C CA   . LEU B 2 56  ? 47.47700 -0.57500  40.62600  1.000 34.30963  ? 54  LEU L CA   1 
ATOM   4072 C C    . LEU B 2 56  ? 48.47600 -1.72000  40.73900  1.000 37.37932  ? 54  LEU L C    1 
ATOM   4073 O O    . LEU B 2 56  ? 49.19200 -1.83200  41.74000  1.000 38.78883  ? 54  LEU L O    1 
ATOM   4074 C CB   . LEU B 2 56  ? 48.18600 0.77300   40.69900  1.000 33.69907  ? 54  LEU L CB   1 
ATOM   4075 C CG   . LEU B 2 56  ? 49.13900 1.09600   39.55100  1.000 35.02845  ? 54  LEU L CG   1 
ATOM   4076 C CD1  . LEU B 2 56  ? 48.37300 1.24200   38.24800  1.000 38.13903  ? 54  LEU L CD1  1 
ATOM   4077 C CD2  . LEU B 2 56  ? 49.92500 2.35900   39.85000  1.000 36.44816  ? 54  LEU L CD2  1 
ATOM   4078 H H    . LEU B 2 56  ? 46.66000 -0.16500  42.36800  1.000 36.45675  ? 54  LEU L H    1 
ATOM   4079 H HA   . LEU B 2 56  ? 47.03100 -0.64000  39.76700  1.000 41.17512  ? 54  LEU L HA   1 
ATOM   4080 H HB2  . LEU B 2 56  ? 47.51000 1.46900   40.71500  1.000 40.44246  ? 54  LEU L HB2  1 
ATOM   4081 H HB3  . LEU B 2 56  ? 48.70600 0.79700   41.51800  1.000 40.44246  ? 54  LEU L HB3  1 
ATOM   4082 H HG   . LEU B 2 56  ? 49.76800 0.36500   39.45000  1.000 42.03771  ? 54  LEU L HG   1 
ATOM   4083 H HD11 . LEU B 2 56  ? 48.97700 1.56500   37.56100  1.000 45.77041  ? 54  LEU L HD11 1 
ATOM   4084 H HD12 . LEU B 2 56  ? 48.01400 0.37800   37.99400  1.000 45.77041  ? 54  LEU L HD12 1 
ATOM   4085 H HD13 . LEU B 2 56  ? 47.65000 1.87600   38.37600  1.000 45.77041  ? 54  LEU L HD13 1 
ATOM   4086 H HD21 . LEU B 2 56  ? 50.52100 2.54300   39.10700  1.000 43.74136  ? 54  LEU L HD21 1 
ATOM   4087 H HD22 . LEU B 2 56  ? 49.30600 3.09600   39.96800  1.000 43.74136  ? 54  LEU L HD22 1 
ATOM   4088 H HD23 . LEU B 2 56  ? 50.43900 2.22600   40.66200  1.000 43.74136  ? 54  LEU L HD23 1 
ATOM   4089 N N    . TYR B 2 57  ? 48.52100 -2.56800  39.71700  1.000 38.67886  ? 55  TYR L N    1 
ATOM   4090 C CA   . TYR B 2 57  ? 49.47300 -3.66800  39.70000  1.000 38.63764  ? 55  TYR L CA   1 
ATOM   4091 C C    . TYR B 2 57  ? 50.90000 -3.13900  39.61500  1.000 42.04854  ? 55  TYR L C    1 
ATOM   4092 O O    . TYR B 2 57  ? 51.17300 -2.11400  38.98400  1.000 37.29738  ? 55  TYR L O    1 
ATOM   4093 C CB   . TYR B 2 57  ? 49.18700 -4.59800  38.52500  1.000 39.49805  ? 55  TYR L CB   1 
ATOM   4094 C CG   . TYR B 2 57  ? 50.06000 -5.82800  38.50500  1.000 43.18756  ? 55  TYR L CG   1 
ATOM   4095 C CD1  . TYR B 2 57  ? 49.91800 -6.81800  39.46700  1.000 46.34890  ? 55  TYR L CD1  1 
ATOM   4096 C CD2  . TYR B 2 57  ? 51.02300 -6.00300  37.52100  1.000 45.59905  ? 55  TYR L CD2  1 
ATOM   4097 C CE1  . TYR B 2 57  ? 50.71100 -7.94600  39.45300  1.000 47.76801  ? 55  TYR L CE1  1 
ATOM   4098 C CE2  . TYR B 2 57  ? 51.82200 -7.12800  37.49900  1.000 45.51853  ? 55  TYR L CE2  1 
ATOM   4099 C CZ   . TYR B 2 57  ? 51.66200 -8.09500  38.46700  1.000 44.92875  ? 55  TYR L CZ   1 
ATOM   4100 O OH   . TYR B 2 57  ? 52.45300 -9.22000  38.45000  1.000 44.61966  ? 55  TYR L OH   1 
ATOM   4101 H H    . TYR B 2 57  ? 48.01200 -2.52800  39.02500  1.000 46.41821  ? 55  TYR L H    1 
ATOM   4102 H HA   . TYR B 2 57  ? 49.38900 -4.18200  40.51800  1.000 46.36874  ? 55  TYR L HA   1 
ATOM   4103 H HB2  . TYR B 2 57  ? 48.26400 -4.89100  38.57500  1.000 47.40124  ? 55  TYR L HB2  1 
ATOM   4104 H HB3  . TYR B 2 57  ? 49.33800 -4.11400  37.69800  1.000 47.40124  ? 55  TYR L HB3  1 
ATOM   4105 H HD1  . TYR B 2 57  ? 49.27600 -6.71900  40.13400  1.000 55.62225  ? 55  TYR L HD1  1 
ATOM   4106 H HD2  . TYR B 2 57  ? 51.13200 -5.35200  36.86700  1.000 54.72243  ? 55  TYR L HD2  1 
ATOM   4107 H HE1  . TYR B 2 57  ? 50.60600 -8.60100  40.10400  1.000 57.32518  ? 55  TYR L HE1  1 
ATOM   4108 H HE2  . TYR B 2 57  ? 52.46400 -7.23200  36.83500  1.000 54.62580  ? 55  TYR L HE2  1 
ATOM   4109 H HH   . TYR B 2 57  ? 53.01000 -9.16900  37.82400  1.000 53.54716  ? 55  TYR L HH   1 
ATOM   4110 N N    . SER B 2 58  ? 51.81700 -3.86100  40.25600  1.000 48.55790  ? 56  SER L N    1 
ATOM   4111 C CA   . SER B 2 58  ? 53.19600 -3.40400  40.36400  1.000 48.60806  ? 56  SER L CA   1 
ATOM   4112 C C    . SER B 2 58  ? 53.82600 -3.23600  38.98700  1.000 43.55853  ? 56  SER L C    1 
ATOM   4113 O O    . SER B 2 58  ? 53.57300 -4.01800  38.06700  1.000 45.94916  ? 56  SER L O    1 
ATOM   4114 C CB   . SER B 2 58  ? 54.01400 -4.39200  41.19800  1.000 56.31808  ? 56  SER L CB   1 
ATOM   4115 O OG   . SER B 2 58  ? 53.90500 -5.70700  40.68000  1.000 59.03814  ? 56  SER L OG   1 
ATOM   4116 H H    . SER B 2 58  ? 51.66500 -4.61800  40.63600  1.000 58.27305  ? 56  SER L H    1 
ATOM   4117 H HA   . SER B 2 58  ? 53.21000 -2.54100  40.80600  1.000 58.33324  ? 56  SER L HA   1 
ATOM   4118 H HB2  . SER B 2 58  ? 54.94500 -4.12300  41.18100  1.000 67.58527  ? 56  SER L HB2  1 
ATOM   4119 H HB3  . SER B 2 58  ? 53.68200 -4.38500  42.10900  1.000 67.58527  ? 56  SER L HB3  1 
ATOM   4120 H HG   . SER B 2 58  ? 54.32800 -6.24400  41.16800  1.000 70.84934  ? 56  SER L HG   1 
ATOM   4121 N N    . GLY B 2 59  ? 54.66100 -2.20600  38.85400  1.000 41.79830  ? 57  GLY L N    1 
ATOM   4122 C CA   . GLY B 2 59  ? 55.32300 -1.90200  37.60900  1.000 41.27905  ? 57  GLY L CA   1 
ATOM   4123 C C    . GLY B 2 59  ? 54.54600 -0.98800  36.68500  1.000 38.01899  ? 57  GLY L C    1 
ATOM   4124 O O    . GLY B 2 59  ? 55.14700 -0.38700  35.78500  1.000 40.13015  ? 57  GLY L O    1 
ATOM   4125 H H    . GLY B 2 59  ? 54.85800 -1.66300  39.49100  1.000 50.16153  ? 57  GLY L H    1 
ATOM   4126 H HA2  . GLY B 2 59  ? 56.17100 -1.47400  37.80400  1.000 49.53842  ? 57  GLY L HA2  1 
ATOM   4127 H HA3  . GLY B 2 59  ? 55.48900 -2.73100  37.13400  1.000 49.53842  ? 57  GLY L HA3  1 
ATOM   4128 N N    . VAL B 2 60  ? 53.24000 -0.87000  36.88600  1.000 38.34869  ? 58  VAL L N    1 
ATOM   4129 C CA   . VAL B 2 60  ? 52.40700 -0.00100  36.03900  1.000 37.38840  ? 58  VAL L CA   1 
ATOM   4130 C C    . VAL B 2 60  ? 52.64600 1.45200   36.44800  1.000 35.85863  ? 58  VAL L C    1 
ATOM   4131 O O    . VAL B 2 60  ? 52.67200 1.74800   37.65300  1.000 35.03823  ? 58  VAL L O    1 
ATOM   4132 C CB   . VAL B 2 60  ? 50.93400 -0.37600  36.17700  1.000 35.14761  ? 58  VAL L CB   1 
ATOM   4133 C CG1  . VAL B 2 60  ? 50.07300 0.54300   35.31100  1.000 34.27818  ? 58  VAL L CG1  1 
ATOM   4134 C CG2  . VAL B 2 60  ? 50.70800 -1.83600  35.79800  1.000 35.62848  ? 58  VAL L CG2  1 
ATOM   4135 H H    . VAL B 2 60  ? 52.80400 -1.28000  37.50400  1.000 46.02200  ? 58  VAL L H    1 
ATOM   4136 H HA   . VAL B 2 60  ? 52.66500 -0.10800  35.11000  1.000 44.86965  ? 58  VAL L HA   1 
ATOM   4137 H HB   . VAL B 2 60  ? 50.66700 -0.26500  37.10300  1.000 42.18071  ? 58  VAL L HB   1 
ATOM   4138 H HG11 . VAL B 2 60  ? 49.14900 0.25200   35.36400  1.000 41.13739  ? 58  VAL L HG11 1 
ATOM   4139 H HG12 . VAL B 2 60  ? 50.15300 1.45200   35.63800  1.000 41.13739  ? 58  VAL L HG12 1 
ATOM   4140 H HG13 . VAL B 2 60  ? 50.38300 0.49300   34.39300  1.000 41.13739  ? 58  VAL L HG13 1 
ATOM   4141 H HG21 . VAL B 2 60  ? 49.76500 -2.04400  35.88900  1.000 42.75775  ? 58  VAL L HG21 1 
ATOM   4142 H HG22 . VAL B 2 60  ? 50.98900 -1.97100  34.87900  1.000 42.75775  ? 58  VAL L HG22 1 
ATOM   4143 H HG23 . VAL B 2 60  ? 51.23000 -2.40000  36.38900  1.000 42.75775  ? 58  VAL L HG23 1 
ATOM   4144 N N    . PRO B 2 61  ? 52.82100 2.36700   35.49900  1.000 33.97763  ? 59  PRO L N    1 
ATOM   4145 C CA   . PRO B 2 61  ? 53.01100 3.77400   35.87300  1.000 36.87842  ? 59  PRO L CA   1 
ATOM   4146 C C    . PRO B 2 61  ? 51.84200 4.29800   36.69300  1.000 35.51935  ? 59  PRO L C    1 
ATOM   4147 O O    . PRO B 2 61  ? 50.68000 3.98200   36.42700  1.000 32.43724  ? 59  PRO L O    1 
ATOM   4148 C CB   . PRO B 2 61  ? 53.11700 4.49300   34.52300  1.000 37.20843  ? 59  PRO L CB   1 
ATOM   4149 C CG   . PRO B 2 61  ? 53.55000 3.44500   33.56500  1.000 34.23818  ? 59  PRO L CG   1 
ATOM   4150 C CD   . PRO B 2 61  ? 52.93300 2.16300   34.04300  1.000 36.36888  ? 59  PRO L CD   1 
ATOM   4151 H HA   . PRO B 2 61  ? 53.83600 3.88500   36.37200  1.000 44.25767  ? 59  PRO L HA   1 
ATOM   4152 H HB2  . PRO B 2 61  ? 52.25400 4.85700   34.27400  1.000 44.65368  ? 59  PRO L HB2  1 
ATOM   4153 H HB3  . PRO B 2 61  ? 53.77400 5.20500   34.57900  1.000 44.65368  ? 59  PRO L HB3  1 
ATOM   4154 H HG2  . PRO B 2 61  ? 53.23400 3.66700   32.67500  1.000 41.08938  ? 59  PRO L HG2  1 
ATOM   4155 H HG3  . PRO B 2 61  ? 54.51800 3.38100   33.56700  1.000 41.08938  ? 59  PRO L HG3  1 
ATOM   4156 H HD2  . PRO B 2 61  ? 52.05900 2.03000   33.64400  1.000 43.64622  ? 59  PRO L HD2  1 
ATOM   4157 H HD3  . PRO B 2 61  ? 53.50700 1.40700   33.84200  1.000 43.64622  ? 59  PRO L HD3  1 
ATOM   4158 N N    . SER B 2 62  ? 52.16200 5.12300   37.69200  1.000 33.34814  ? 60  SER L N    1 
ATOM   4159 C CA   . SER B 2 62  ? 51.14600 5.61100   38.61400  1.000 34.08816  ? 60  SER L CA   1 
ATOM   4160 C C    . SER B 2 62  ? 50.20700 6.62500   37.97900  1.000 32.96813  ? 60  SER L C    1 
ATOM   4161 O O    . SER B 2 62  ? 49.20600 6.98800   38.60600  1.000 33.92761  ? 60  SER L O    1 
ATOM   4162 C CB   . SER B 2 62  ? 51.81000 6.22700   39.84700  1.000 33.92768  ? 60  SER L CB   1 
ATOM   4163 O OG   . SER B 2 62  ? 52.66100 7.29900   39.48500  1.000 35.25810  ? 60  SER L OG   1 
ATOM   4164 H H    . SER B 2 62  ? 52.95600 5.41100   37.85300  1.000 40.02133  ? 60  SER L H    1 
ATOM   4165 H HA   . SER B 2 62  ? 50.61200 4.85600   38.90700  1.000 40.90936  ? 60  SER L HA   1 
ATOM   4166 H HB2  . SER B 2 62  ? 51.12000 6.56000   40.44200  1.000 40.71678  ? 60  SER L HB2  1 
ATOM   4167 H HB3  . SER B 2 62  ? 52.33400 5.54600   40.29600  1.000 40.71678  ? 60  SER L HB3  1 
ATOM   4168 H HG   . SER B 2 62  ? 52.67800 7.38400   38.65000  1.000 42.31330  ? 60  SER L HG   1 
ATOM   4169 N N    . ARG B 2 63  ? 50.48900 7.08800   36.76000  1.000 30.73728  ? 61  ARG L N    1 
ATOM   4170 C CA   . ARG B 2 63  ? 49.55000 7.98100   36.09500  1.000 31.50844  ? 61  ARG L CA   1 
ATOM   4171 C C    . ARG B 2 63  ? 48.23700 7.28500   35.75800  1.000 28.97673  ? 61  ARG L C    1 
ATOM   4172 O O    . ARG B 2 63  ? 47.25100 7.96600   35.45800  1.000 30.19770  ? 61  ARG L O    1 
ATOM   4173 C CB   . ARG B 2 63  ? 50.17300 8.56700   34.82900  1.000 31.19757  ? 61  ARG L CB   1 
ATOM   4174 C CG   . ARG B 2 63  ? 50.59500 7.54400   33.78600  1.000 32.68858  ? 61  ARG L CG   1 
ATOM   4175 C CD   . ARG B 2 63  ? 51.04800 8.24500   32.50600  1.000 33.87875  ? 61  ARG L CD   1 
ATOM   4176 N NE   . ARG B 2 63  ? 51.57000 7.31300   31.51500  1.000 35.81974  ? 61  ARG L NE   1 
ATOM   4177 C CZ   . ARG B 2 63  ? 52.78800 6.78900   31.55100  1.000 36.02926  ? 61  ARG L CZ   1 
ATOM   4178 N NH1  . ARG B 2 63  ? 53.63600 7.07700   32.52500  1.000 36.83899  ? 61  ARG L NH1  1 
ATOM   4179 N NH2  . ARG B 2 63  ? 53.16200 5.95000   30.59100  1.000 34.73834  ? 61  ARG L NH2  1 
ATOM   4180 H H    . ARG B 2 63  ? 51.19900 6.90300   36.31100  1.000 36.88830  ? 61  ARG L H    1 
ATOM   4181 H HA   . ARG B 2 63  ? 49.35300 8.72100   36.69100  1.000 37.81370  ? 61  ARG L HA   1 
ATOM   4182 H HB2  . ARG B 2 63  ? 49.52500 9.15600   34.41200  1.000 37.44065  ? 61  ARG L HB2  1 
ATOM   4183 H HB3  . ARG B 2 63  ? 50.96400 9.06800   35.08000  1.000 37.44065  ? 61  ARG L HB3  1 
ATOM   4184 H HG2  . ARG B 2 63  ? 51.33400 7.01600   34.12700  1.000 39.22987  ? 61  ARG L HG2  1 
ATOM   4185 H HG3  . ARG B 2 63  ? 49.84500 6.96600   33.57400  1.000 39.22987  ? 61  ARG L HG3  1 
ATOM   4186 H HD2  . ARG B 2 63  ? 50.29200 8.70900   32.11400  1.000 40.65807  ? 61  ARG L HD2  1 
ATOM   4187 H HD3  . ARG B 2 63  ? 51.75000 8.87800   32.72300  1.000 40.65807  ? 61  ARG L HD3  1 
ATOM   4188 H HE   . ARG B 2 63  ? 51.05500 7.08700   30.86400  1.000 42.98726  ? 61  ARG L HE   1 
ATOM   4189 H HH11 . ARG B 2 63  ? 53.40200 7.61500   33.15400  1.000 44.21036  ? 61  ARG L HH11 1 
ATOM   4190 H HH12 . ARG B 2 63  ? 54.42100 6.72700   32.52900  1.000 44.21036  ? 61  ARG L HH12 1 
ATOM   4191 H HH21 . ARG B 2 63  ? 52.61600 5.75300   29.95600  1.000 41.68958  ? 61  ARG L HH21 1 
ATOM   4192 H HH22 . ARG B 2 63  ? 53.94900 5.60500   30.60400  1.000 41.68958  ? 61  ARG L HH22 1 
ATOM   4193 N N    . PHE B 2 64  ? 48.20000 5.95300   35.80000  1.000 28.37629  ? 62  PHE L N    1 
ATOM   4194 C CA   . PHE B 2 64  ? 46.96300 5.19900   35.63900  1.000 33.20913  ? 62  PHE L CA   1 
ATOM   4195 C C    . PHE B 2 64  ? 46.30600 4.98400   36.99700  1.000 30.44673  ? 62  PHE L C    1 
ATOM   4196 O O    . PHE B 2 64  ? 46.94700 4.48300   37.92700  1.000 33.58833  ? 62  PHE L O    1 
ATOM   4197 C CB   . PHE B 2 64  ? 47.22800 3.84100   34.98600  1.000 29.56734  ? 62  PHE L CB   1 
ATOM   4198 C CG   . PHE B 2 64  ? 47.72400 3.93300   33.58200  1.000 27.20696  ? 62  PHE L CG   1 
ATOM   4199 C CD1  . PHE B 2 64  ? 46.84700 4.19800   32.54600  1.000 27.81852  ? 62  PHE L CD1  1 
ATOM   4200 C CD2  . PHE B 2 64  ? 49.06500 3.75100   33.29200  1.000 29.34768  ? 62  PHE L CD2  1 
ATOM   4201 C CE1  . PHE B 2 64  ? 47.29700 4.28600   31.25000  1.000 24.62672  ? 62  PHE L CE1  1 
ATOM   4202 C CE2  . PHE B 2 64  ? 49.52100 3.83600   31.99400  1.000 33.13954  ? 62  PHE L CE2  1 
ATOM   4203 C CZ   . PHE B 2 64  ? 48.63500 4.10400   30.97200  1.000 27.97788  ? 62  PHE L CZ   1 
ATOM   4204 H H    . PHE B 2 64  ? 48.89200 5.45700   35.92400  1.000 34.05512  ? 62  PHE L H    1 
ATOM   4205 H HA   . PHE B 2 64  ? 46.36100 5.70500   35.07000  1.000 39.85452  ? 62  PHE L HA   1 
ATOM   4206 H HB2  . PHE B 2 64  ? 47.89900 3.37200   35.50600  1.000 35.48437  ? 62  PHE L HB2  1 
ATOM   4207 H HB3  . PHE B 2 64  ? 46.40200 3.33400   34.97500  1.000 35.48437  ? 62  PHE L HB3  1 
ATOM   4208 H HD1  . PHE B 2 64  ? 45.94300 4.31800   32.72900  1.000 33.38580  ? 62  PHE L HD1  1 
ATOM   4209 H HD2  . PHE B 2 64  ? 49.66400 3.57000   33.98000  1.000 35.22079  ? 62  PHE L HD2  1 
ATOM   4210 H HE1  . PHE B 2 64  ? 46.69900 4.46700   30.56200  1.000 29.55564  ? 62  PHE L HE1  1 
ATOM   4211 H HE2  . PHE B 2 64  ? 50.42400 3.71400   31.80900  1.000 39.77101  ? 62  PHE L HE2  1 
ATOM   4212 H HZ   . PHE B 2 64  ? 48.94000 4.16200   30.09500  1.000 33.57703  ? 62  PHE L HZ   1 
ATOM   4213 N N    . SER B 2 65  ? 45.02700 5.33700   37.10600  1.000 28.59629  ? 63  SER L N    1 
ATOM   4214 C CA   . SER B 2 65  ? 44.29700 5.16500   38.35500  1.000 32.07734  ? 63  SER L CA   1 
ATOM   4215 C C    . SER B 2 65  ? 42.87300 4.72200   38.06400  1.000 29.30709  ? 63  SER L C    1 
ATOM   4216 O O    . SER B 2 65  ? 42.24900 5.20000   37.11300  1.000 29.59828  ? 63  SER L O    1 
ATOM   4217 C CB   . SER B 2 65  ? 44.27800 6.46000   39.18300  1.000 32.40637  ? 63  SER L CB   1 
ATOM   4218 O OG   . SER B 2 65  ? 43.51800 7.47000   38.54300  1.000 32.71765  ? 63  SER L OG   1 
ATOM   4219 H H    . SER B 2 65  ? 44.56100 5.67800   36.46900  1.000 34.31912  ? 63  SER L H    1 
ATOM   4220 H HA   . SER B 2 65  ? 44.72700 4.47100   38.87900  1.000 38.49638  ? 63  SER L HA   1 
ATOM   4221 H HB2  . SER B 2 65  ? 43.88500 6.27300   40.04900  1.000 38.89121  ? 63  SER L HB2  1 
ATOM   4222 H HB3  . SER B 2 65  ? 45.18900 6.77500   39.29300  1.000 38.89121  ? 63  SER L HB3  1 
ATOM   4223 H HG   . SER B 2 65  ? 43.96000 7.80700   37.91300  1.000 39.26475  ? 63  SER L HG   1 
ATOM   4224 N N    . GLY B 2 66  ? 42.36700 3.80800   38.88900  1.000 26.94575  ? 64  GLY L N    1 
ATOM   4225 C CA   . GLY B 2 66  ? 41.00500 3.31900   38.77900  1.000 27.49692  ? 64  GLY L CA   1 
ATOM   4226 C C    . GLY B 2 66  ? 40.16400 3.78000   39.95400  1.000 33.47950  ? 64  GLY L C    1 
ATOM   4227 O O    . GLY B 2 66  ? 40.66200 3.92600   41.07300  1.000 31.44736  ? 64  GLY L O    1 
ATOM   4228 H H    . GLY B 2 66  ? 42.80800 3.45100   39.53500  1.000 32.33847  ? 64  GLY L H    1 
ATOM   4229 H HA2  . GLY B 2 66  ? 40.60400 3.65100   37.96000  1.000 32.99988  ? 64  GLY L HA2  1 
ATOM   4230 H HA3  . GLY B 2 66  ? 41.00700 2.34900   38.75900  1.000 32.99988  ? 64  GLY L HA3  1 
ATOM   4231 N N    . SER B 2 67  ? 38.88200 4.01100   39.69400  1.000 28.58666  ? 65  SER L N    1 
ATOM   4232 C CA   . SER B 2 67  ? 37.95900 4.44800   40.73200  1.000 31.79878  ? 65  SER L CA   1 
ATOM   4233 C C    . SER B 2 67  ? 36.55000 4.03800   40.32600  1.000 34.46073  ? 65  SER L C    1 
ATOM   4234 O O    . SER B 2 67  ? 36.33400 3.44000   39.26700  1.000 28.02692  ? 65  SER L O    1 
ATOM   4235 C CB   . SER B 2 67  ? 38.05800 5.95900   40.95800  1.000 35.24842  ? 65  SER L CB   1 
ATOM   4236 O OG   . SER B 2 67  ? 37.69500 6.67000   39.78800  1.000 37.73033  ? 65  SER L OG   1 
ATOM   4237 H H    . SER B 2 67  ? 38.52000 3.92000   38.91900  1.000 34.30756  ? 65  SER L H    1 
ATOM   4238 H HA   . SER B 2 67  ? 38.18300 3.99800   41.56100  1.000 38.16211  ? 65  SER L HA   1 
ATOM   4239 H HB2  . SER B 2 67  ? 37.45900 6.21000   41.67800  1.000 42.30167  ? 65  SER L HB2  1 
ATOM   4240 H HB3  . SER B 2 67  ? 38.97200 6.18300   41.19300  1.000 42.30167  ? 65  SER L HB3  1 
ATOM   4241 H HG   . SER B 2 67  ? 38.22800 6.48900   39.16500  1.000 45.27996  ? 65  SER L HG   1 
ATOM   4242 N N    . GLY B 2 68  ? 35.59500 4.35900   41.18600  1.000 31.71830  ? 66  GLY L N    1 
ATOM   4243 C CA   . GLY B 2 68  ? 34.19700 4.07600   40.94700  1.000 32.75762  ? 66  GLY L CA   1 
ATOM   4244 C C    . GLY B 2 68  ? 33.60000 3.21000   42.03400  1.000 37.44944  ? 66  GLY L C    1 
ATOM   4245 O O    . GLY B 2 68  ? 34.26400 2.80800   42.99400  1.000 36.40822  ? 66  GLY L O    1 
ATOM   4246 H H    . GLY B 2 68  ? 35.74000 4.75400   41.93600  1.000 38.06553  ? 66  GLY L H    1 
ATOM   4247 H HA2  . GLY B 2 68  ? 33.70000 4.90800   40.91100  1.000 39.31271  ? 66  GLY L HA2  1 
ATOM   4248 H HA3  . GLY B 2 68  ? 34.10100 3.61400   40.10000  1.000 39.31271  ? 66  GLY L HA3  1 
ATOM   4249 N N    . SER B 2 69  ? 32.31400 2.91900   41.86700  1.000 37.90788  ? 67  SER L N    1 
ATOM   4250 C CA   . SER B 2 69  ? 31.56100 2.14800   42.84300  1.000 41.25813  ? 67  SER L CA   1 
ATOM   4251 C C    . SER B 2 69  ? 30.23900 1.73400   42.21800  1.000 39.36832  ? 67  SER L C    1 
ATOM   4252 O O    . SER B 2 69  ? 29.76500 2.35400   41.26100  1.000 35.90670  ? 67  SER L O    1 
ATOM   4253 C CB   . SER B 2 69  ? 31.31600 2.95500   44.12100  1.000 47.14806  ? 67  SER L CB   1 
ATOM   4254 O OG   . SER B 2 69  ? 30.65000 4.17000   43.81800  1.000 46.62730  ? 67  SER L OG   1 
ATOM   4255 H H    . SER B 2 69  ? 31.84900 3.16100   41.18500  1.000 45.49302  ? 67  SER L H    1 
ATOM   4256 H HA   . SER B 2 69  ? 32.05500 1.34500   43.07200  1.000 49.51332  ? 67  SER L HA   1 
ATOM   4257 H HB2  . SER B 2 69  ? 30.76500 2.43300   44.72500  1.000 56.58124  ? 67  SER L HB2  1 
ATOM   4258 H HB3  . SER B 2 69  ? 32.16800 3.15500   44.53800  1.000 56.58124  ? 67  SER L HB3  1 
ATOM   4259 H HG   . SER B 2 69  ? 30.56000 4.63000   44.51500  1.000 55.95633  ? 67  SER L HG   1 
ATOM   4260 N N    . GLY B 2 70  ? 29.64400 0.68500   42.78000  1.000 40.52892  ? 68  GLY L N    1 
ATOM   4261 C CA   . GLY B 2 70  ? 28.36200 0.20300   42.31300  1.000 38.32896  ? 68  GLY L CA   1 
ATOM   4262 C C    . GLY B 2 70  ? 28.43700 -0.35600  40.91000  1.000 34.17856  ? 68  GLY L C    1 
ATOM   4263 O O    . GLY B 2 70  ? 28.96900 -1.45000  40.70200  1.000 35.80007  ? 68  GLY L O    1 
ATOM   4264 H H    . GLY B 2 70  ? 29.97000 0.23600   43.43800  1.000 48.63828  ? 68  GLY L H    1 
ATOM   4265 H HA2  . GLY B 2 70  ? 28.04700 -0.49800  42.90600  1.000 45.99833  ? 68  GLY L HA2  1 
ATOM   4266 H HA3  . GLY B 2 70  ? 27.72300 0.93200   42.31900  1.000 45.99833  ? 68  GLY L HA3  1 
ATOM   4267 N N    . THR B 2 71  ? 27.90100 0.38500   39.93700  1.000 34.23776  ? 69  THR L N    1 
ATOM   4268 C CA   . THR B 2 71  ? 27.97000 -0.01600  38.53800  1.000 34.88876  ? 69  THR L CA   1 
ATOM   4269 C C    . THR B 2 71  ? 28.58600 1.07600   37.67000  1.000 33.63769  ? 69  THR L C    1 
ATOM   4270 O O    . THR B 2 71  ? 28.38400 1.07400   36.45300  1.000 35.79897  ? 69  THR L O    1 
ATOM   4271 C CB   . THR B 2 71  ? 26.58200 -0.38500  38.00400  1.000 31.90810  ? 69  THR L CB   1 
ATOM   4272 O OG1  . THR B 2 71  ? 25.70200 0.74000   38.12500  1.000 34.76767  ? 69  THR L OG1  1 
ATOM   4273 C CG2  . THR B 2 71  ? 26.01400 -1.56500  38.77600  1.000 29.35850  ? 69  THR L CG2  1 
ATOM   4274 H H    . THR B 2 71  ? 27.49000 1.12900   40.06800  1.000 41.08888  ? 69  THR L H    1 
ATOM   4275 H HA   . THR B 2 71  ? 28.53200 -0.80300  38.47300  1.000 41.87008  ? 69  THR L HA   1 
ATOM   4276 H HB   . THR B 2 71  ? 26.64800 -0.63600  37.06900  1.000 38.29330  ? 69  THR L HB   1 
ATOM   4277 H HG1  . THR B 2 71  ? 24.93800 0.53900   37.84200  1.000 41.72477  ? 69  THR L HG1  1 
ATOM   4278 H HG21 . THR B 2 71  ? 25.22700 -1.90900  38.32500  1.000 35.23377  ? 69  THR L HG21 1 
ATOM   4279 H HG22 . THR B 2 71  ? 26.67600 -2.27100  38.83600  1.000 35.23377  ? 69  THR L HG22 1 
ATOM   4280 H HG23 . THR B 2 71  ? 25.76800 -1.28800  39.67200  1.000 35.23377  ? 69  THR L HG23 1 
ATOM   4281 N N    . ASP B 2 72  ? 29.32500 2.01000   38.26800  1.000 33.82746  ? 70  ASP L N    1 
ATOM   4282 C CA   . ASP B 2 72  ? 29.96000 3.10300   37.53900  1.000 34.03798  ? 70  ASP L CA   1 
ATOM   4283 C C    . ASP B 2 72  ? 31.44200 3.11100   37.87800  1.000 34.45985  ? 70  ASP L C    1 
ATOM   4284 O O    . ASP B 2 72  ? 31.81300 3.32200   39.03700  1.000 32.65827  ? 70  ASP L O    1 
ATOM   4285 C CB   . ASP B 2 72  ? 29.33400 4.45700   37.89100  1.000 40.76848  ? 70  ASP L CB   1 
ATOM   4286 C CG   . ASP B 2 72  ? 27.83700 4.50200   37.63400  1.000 55.22780  ? 70  ASP L CG   1 
ATOM   4287 O OD1  . ASP B 2 72  ? 27.28900 3.54000   37.05600  1.000 55.79907  ? 70  ASP L OD1  1 
ATOM   4288 O OD2  . ASP B 2 72  ? 27.20500 5.51000   38.01600  1.000 72.34790  ? 70  ASP L OD2  1 
ATOM   4289 H H    . ASP B 2 72  ? 29.47600 2.03100   39.11400  1.000 40.59653  ? 70  ASP L H    1 
ATOM   4290 H HA   . ASP B 2 72  ? 29.85100 2.95500   36.58600  1.000 40.84915  ? 70  ASP L HA   1 
ATOM   4291 H HB2  . ASP B 2 72  ? 29.48100 4.63800   38.83200  1.000 48.92575  ? 70  ASP L HB2  1 
ATOM   4292 H HB3  . ASP B 2 72  ? 29.75100 5.14700   37.35100  1.000 48.92575  ? 70  ASP L HB3  1 
ATOM   4293 N N    . PHE B 2 73  ? 32.28400 2.89000   36.87100  1.000 28.28695  ? 71  PHE L N    1 
ATOM   4294 C CA   . PHE B 2 73  ? 33.72100 2.77500   37.06400  1.000 27.10693  ? 71  PHE L CA   1 
ATOM   4295 C C    . PHE B 2 73  ? 34.44200 3.69400   36.09200  1.000 27.43837  ? 71  PHE L C    1 
ATOM   4296 O O    . PHE B 2 73  ? 33.92200 4.04600   35.03000  1.000 28.21915  ? 71  PHE L O    1 
ATOM   4297 C CB   . PHE B 2 73  ? 34.18600 1.32700   36.88100  1.000 24.94602  ? 71  PHE L CB   1 
ATOM   4298 C CG   . PHE B 2 73  ? 33.40800 0.34800   37.70100  1.000 30.44925  ? 71  PHE L CG   1 
ATOM   4299 C CD1  . PHE B 2 73  ? 33.75200 0.10200   39.01800  1.000 29.72847  ? 71  PHE L CD1  1 
ATOM   4300 C CD2  . PHE B 2 73  ? 32.31300 -0.30700  37.16500  1.000 28.89777  ? 71  PHE L CD2  1 
ATOM   4301 C CE1  . PHE B 2 73  ? 33.02900 -0.78900  39.77800  1.000 29.35770  ? 71  PHE L CE1  1 
ATOM   4302 C CE2  . PHE B 2 73  ? 31.58500 -1.19800  37.92300  1.000 29.67875  ? 71  PHE L CE2  1 
ATOM   4303 C CZ   . PHE B 2 73  ? 31.94300 -1.44000  39.22900  1.000 30.27925  ? 71  PHE L CZ   1 
ATOM   4304 H H    . PHE B 2 73  ? 32.03900 2.80200   36.05100  1.000 33.94791  ? 71  PHE L H    1 
ATOM   4305 H HA   . PHE B 2 73  ? 33.95600 3.05700   37.96200  1.000 32.53189  ? 71  PHE L HA   1 
ATOM   4306 H HB2  . PHE B 2 73  ? 34.08600 1.08100   35.94800  1.000 29.93879  ? 71  PHE L HB2  1 
ATOM   4307 H HB3  . PHE B 2 73  ? 35.11800 1.26200   37.14300  1.000 29.93879  ? 71  PHE L HB3  1 
ATOM   4308 H HD1  . PHE B 2 73  ? 34.48000 0.54300   39.39400  1.000 35.67774  ? 71  PHE L HD1  1 
ATOM   4309 H HD2  . PHE B 2 73  ? 32.06700 -0.14400  36.28300  1.000 34.68090  ? 71  PHE L HD2  1 
ATOM   4310 H HE1  . PHE B 2 73  ? 33.27200 -0.95300  40.66100  1.000 35.23281  ? 71  PHE L HE1  1 
ATOM   4311 H HE2  . PHE B 2 73  ? 30.85200 -1.63400  37.55200  1.000 35.61807  ? 71  PHE L HE2  1 
ATOM   4312 H HZ   . PHE B 2 73  ? 31.45400 -2.04300  39.74200  1.000 36.33867  ? 71  PHE L HZ   1 
ATOM   4313 N N    . THR B 2 74  ? 35.65600 4.07700   36.47200  1.000 23.34456  ? 72  THR L N    1 
ATOM   4314 C CA   . THR B 2 74  ? 36.40500 5.08200   35.73700  1.000 26.22762  ? 72  THR L CA   1 
ATOM   4315 C C    . THR B 2 74  ? 37.88500 4.74000   35.74900  1.000 27.71936  ? 72  THR L C    1 
ATOM   4316 O O    . THR B 2 74  ? 38.44100 4.36200   36.78500  1.000 26.23766  ? 72  THR L O    1 
ATOM   4317 C CB   . THR B 2 74  ? 36.18400 6.48200   36.33700  1.000 29.79950  ? 72  THR L CB   1 
ATOM   4318 O OG1  . THR B 2 74  ? 34.78900 6.81300   36.28800  1.000 28.21732  ? 72  THR L OG1  1 
ATOM   4319 C CG2  . THR B 2 74  ? 36.97200 7.53200   35.56700  1.000 29.62905  ? 72  THR L CG2  1 
ATOM   4320 H H    . THR B 2 74  ? 36.06900 3.76500   37.15900  1.000 28.01704  ? 72  THR L H    1 
ATOM   4321 H HA   . THR B 2 74  ? 36.11200 5.08800   34.81200  1.000 31.47671  ? 72  THR L HA   1 
ATOM   4322 H HB   . THR B 2 74  ? 36.48900 6.48500   37.25700  1.000 35.76297  ? 72  THR L HB   1 
ATOM   4323 H HG1  . THR B 2 74  ? 34.66600 7.58400   36.59700  1.000 33.86436  ? 72  THR L HG1  1 
ATOM   4324 H HG21 . THR B 2 74  ? 36.75100 8.41800   35.89300  1.000 35.55843  ? 72  THR L HG21 1 
ATOM   4325 H HG22 . THR B 2 74  ? 37.92300 7.38200   35.68100  1.000 35.55843  ? 72  THR L HG22 1 
ATOM   4326 H HG23 . THR B 2 74  ? 36.75600 7.48200   34.62200  1.000 35.55843  ? 72  THR L HG23 1 
ATOM   4327 N N    . LEU B 2 75  ? 38.50400 4.86800   34.57800  1.000 25.34802  ? 73  LEU L N    1 
ATOM   4328 C CA   . LEU B 2 75  ? 39.95000 4.83000   34.40800  1.000 24.07714  ? 73  LEU L CA   1 
ATOM   4329 C C    . LEU B 2 75  ? 40.42900 6.24600   34.12200  1.000 22.98560  ? 73  LEU L C    1 
ATOM   4330 O O    . LEU B 2 75  ? 39.84300 6.94200   33.28500  1.000 27.45912  ? 73  LEU L O    1 
ATOM   4331 C CB   . LEU B 2 75  ? 40.34300 3.90100   33.25800  1.000 23.91830  ? 73  LEU L CB   1 
ATOM   4332 C CG   . LEU B 2 75  ? 41.83800 3.78100   32.96400  1.000 24.08873  ? 73  LEU L CG   1 
ATOM   4333 C CD1  . LEU B 2 75  ? 42.52200 3.06300   34.10800  1.000 22.44714  ? 73  LEU L CD1  1 
ATOM   4334 C CD2  . LEU B 2 75  ? 42.09400 3.06000   31.64400  1.000 22.16866  ? 73  LEU L CD2  1 
ATOM   4335 H H    . LEU B 2 75  ? 38.08700 4.98300   33.83500  1.000 30.42120  ? 73  LEU L H    1 
ATOM   4336 H HA   . LEU B 2 75  ? 40.37500 4.50300   35.21600  1.000 28.89614  ? 73  LEU L HA   1 
ATOM   4337 H HB2  . LEU B 2 75  ? 40.02100 3.01100   33.46700  1.000 28.70553  ? 73  LEU L HB2  1 
ATOM   4338 H HB3  . LEU B 2 75  ? 39.91800 4.22700   32.44900  1.000 28.70553  ? 73  LEU L HB3  1 
ATOM   4339 H HG   . LEU B 2 75  ? 42.21700 4.67000   32.87600  1.000 28.91005  ? 73  LEU L HG   1 
ATOM   4340 H HD11 . LEU B 2 75  ? 43.46500 2.97000   33.90400  1.000 26.94013  ? 73  LEU L HD11 1 
ATOM   4341 H HD12 . LEU B 2 75  ? 42.40800 3.58100   34.91900  1.000 26.94013  ? 73  LEU L HD12 1 
ATOM   4342 H HD13 . LEU B 2 75  ? 42.11900 2.18700   34.21600  1.000 26.94013  ? 73  LEU L HD13 1 
ATOM   4343 H HD21 . LEU B 2 75  ? 43.05000 2.96300   31.51700  1.000 26.60596  ? 73  LEU L HD21 1 
ATOM   4344 H HD22 . LEU B 2 75  ? 41.67400 2.18700   31.67500  1.000 26.60596  ? 73  LEU L HD22 1 
ATOM   4345 H HD23 . LEU B 2 75  ? 41.71600 3.58300   30.92000  1.000 26.60596  ? 73  LEU L HD23 1 
ATOM   4346 N N    . THR B 2 76  ? 41.48300 6.67400   34.81200  1.000 25.91773  ? 74  THR L N    1 
ATOM   4347 C CA   . THR B 2 76  ? 42.03100 8.00800   34.61700  1.000 26.21784  ? 74  THR L CA   1 
ATOM   4348 C C    . THR B 2 76  ? 43.51600 7.91000   34.31700  1.000 27.52865  ? 74  THR L C    1 
ATOM   4349 O O    . THR B 2 76  ? 44.25700 7.22700   35.03400  1.000 27.95776  ? 74  THR L O    1 
ATOM   4350 C CB   . THR B 2 76  ? 41.81400 8.90200   35.84500  1.000 27.14823  ? 74  THR L CB   1 
ATOM   4351 O OG1  . THR B 2 76  ? 40.41700 8.96900   36.14500  1.000 27.27802  ? 74  THR L OG1  1 
ATOM   4352 C CG2  . THR B 2 76  ? 42.32800 10.31000  35.58100  1.000 26.53696  ? 74  THR L CG2  1 
ATOM   4353 H H    . THR B 2 76  ? 41.89800 6.20500   35.40100  1.000 31.10485  ? 74  THR L H    1 
ATOM   4354 H HA   . THR B 2 76  ? 41.58500 8.41600   33.85800  1.000 31.46498  ? 74  THR L HA   1 
ATOM   4355 H HB   . THR B 2 76  ? 42.29700 8.53100   36.60000  1.000 32.58145  ? 74  THR L HB   1 
ATOM   4356 H HG1  . THR B 2 76  ? 40.15500 8.23500   36.45900  1.000 32.73719  ? 74  THR L HG1  1 
ATOM   4357 H HG21 . THR B 2 76  ? 42.13800 10.88100  36.34200  1.000 31.84793  ? 74  THR L HG21 1 
ATOM   4358 H HG22 . THR B 2 76  ? 43.28600 10.29100  35.43300  1.000 31.84793  ? 74  THR L HG22 1 
ATOM   4359 H HG23 . THR B 2 76  ? 41.89600 10.67900  34.79500  1.000 31.84793  ? 74  THR L HG23 1 
ATOM   4360 N N    . ILE B 2 77  ? 43.93700 8.59500   33.25900  1.000 27.01769  ? 75  ILE L N    1 
ATOM   4361 C CA   . ILE B 2 77  ? 45.34100 8.79500   32.93000  1.000 28.22799  ? 75  ILE L CA   1 
ATOM   4362 C C    . ILE B 2 77  ? 45.64400 10.25600  33.22900  1.000 29.93795  ? 75  ILE L C    1 
ATOM   4363 O O    . ILE B 2 77  ? 45.16100 11.15500  32.53000  1.000 31.54835  ? 75  ILE L O    1 
ATOM   4364 C CB   . ILE B 2 77  ? 45.64900 8.45700   31.46700  1.000 26.56663  ? 75  ILE L CB   1 
ATOM   4365 C CG1  . ILE B 2 77  ? 44.90000 7.19800   31.03300  1.000 26.07793  ? 75  ILE L CG1  1 
ATOM   4366 C CG2  . ILE B 2 77  ? 47.14700 8.26800   31.28900  1.000 28.62718  ? 75  ILE L CG2  1 
ATOM   4367 C CD1  . ILE B 2 77  ? 45.16800 6.79200   29.59400  1.000 24.65804  ? 75  ILE L CD1  1 
ATOM   4368 H H    . ILE B 2 77  ? 43.40500 8.96700   32.69500  1.000 32.42480  ? 75  ILE L H    1 
ATOM   4369 H HA   . ILE B 2 77  ? 45.89400 8.22700   33.48900  1.000 33.87716  ? 75  ILE L HA   1 
ATOM   4370 H HB   . ILE B 2 77  ? 45.35000 9.19400   30.91100  1.000 31.88353  ? 75  ILE L HB   1 
ATOM   4371 H HG12 . ILE B 2 77  ? 45.17100 6.46100   31.60300  1.000 31.29708  ? 75  ILE L HG12 1 
ATOM   4372 H HG13 . ILE B 2 77  ? 43.94700 7.35400   31.12400  1.000 31.29708  ? 75  ILE L HG13 1 
ATOM   4373 H HG21 . ILE B 2 77  ? 47.34300 8.16600   30.34500  1.000 34.35618  ? 75  ILE L HG21 1 
ATOM   4374 H HG22 . ILE B 2 77  ? 47.60800 9.04600   31.64000  1.000 34.35618  ? 75  ILE L HG22 1 
ATOM   4375 H HG23 . ILE B 2 77  ? 47.42500 7.47300   31.77200  1.000 34.35618  ? 75  ILE L HG23 1 
ATOM   4376 H HD11 . ILE B 2 77  ? 44.55100 6.08700   29.34400  1.000 29.59322  ? 75  ILE L HD11 1 
ATOM   4377 H HD12 . ILE B 2 77  ? 45.03900 7.56300   29.01900  1.000 29.59322  ? 75  ILE L HD12 1 
ATOM   4378 H HD13 . ILE B 2 77  ? 46.08100 6.47400   29.52000  1.000 29.59322  ? 75  ILE L HD13 1 
ATOM   4379 N N    . SER B 2 78  ? 46.43700 10.49700  34.27100  1.000 32.58888  ? 76  SER L N    1 
ATOM   4380 C CA   . SER B 2 78  ? 46.62800 11.86400  34.74400  1.000 35.02844  ? 76  SER L CA   1 
ATOM   4381 C C    . SER B 2 78  ? 47.37400 12.70900  33.72000  1.000 35.71830  ? 76  SER L C    1 
ATOM   4382 O O    . SER B 2 78  ? 46.98400 13.85100  33.45000  1.000 39.78952  ? 76  SER L O    1 
ATOM   4383 C CB   . SER B 2 78  ? 47.37200 11.84700  36.07600  1.000 34.13840  ? 76  SER L CB   1 
ATOM   4384 O OG   . SER B 2 78  ? 48.54800 11.06400  35.97900  1.000 36.74851  ? 76  SER L OG   1 
ATOM   4385 H H    . SER B 2 78  ? 46.86800 9.89900   34.71400  1.000 39.11022  ? 76  SER L H    1 
ATOM   4386 H HA   . SER B 2 78  ? 45.75900 12.27200  34.88400  1.000 42.03770  ? 76  SER L HA   1 
ATOM   4387 H HB2  . SER B 2 78  ? 47.61600 12.75500  36.31400  1.000 40.96965  ? 76  SER L HB2  1 
ATOM   4388 H HB3  . SER B 2 78  ? 46.79500 11.46900  36.75700  1.000 40.96965  ? 76  SER L HB3  1 
ATOM   4389 H HG   . SER B 2 78  ? 48.91900 11.00800  36.73100  1.000 44.10178  ? 76  SER L HG   1 
ATOM   4390 N N    . SER B 2 79  ? 48.44300 12.16800  33.13900  1.000 33.64790  ? 77  SER L N    1 
ATOM   4391 C CA   . SER B 2 79  ? 49.27900 12.90600  32.19100  1.000 35.46788  ? 77  SER L CA   1 
ATOM   4392 C C    . SER B 2 79  ? 49.61600 11.96600  31.03700  1.000 33.36757  ? 77  SER L C    1 
ATOM   4393 O O    . SER B 2 79  ? 50.52100 11.13600  31.15200  1.000 33.09741  ? 77  SER L O    1 
ATOM   4394 C CB   . SER B 2 79  ? 50.53800 13.43000  32.87000  1.000 38.80926  ? 77  SER L CB   1 
ATOM   4395 O OG   . SER B 2 79  ? 51.29000 14.24300  31.99000  1.000 40.47760  ? 77  SER L OG   1 
ATOM   4396 H H    . SER B 2 79  ? 48.71000 11.36300  33.27900  1.000 40.38105  ? 77  SER L H    1 
ATOM   4397 H HA   . SER B 2 79  ? 48.78100 13.65800  31.83500  1.000 42.56503  ? 77  SER L HA   1 
ATOM   4398 H HB2  . SER B 2 79  ? 50.28200 13.95700  33.64300  1.000 46.57469  ? 77  SER L HB2  1 
ATOM   4399 H HB3  . SER B 2 79  ? 51.08300 12.67700  33.14700  1.000 46.57469  ? 77  SER L HB3  1 
ATOM   4400 H HG   . SER B 2 79  ? 51.97500 14.53200  32.38100  1.000 48.57669  ? 77  SER L HG   1 
ATOM   4401 N N    . LEU B 2 80  ? 48.89900 12.11800  29.92600  1.000 32.55745  ? 78  LEU L N    1 
ATOM   4402 C CA   . LEU B 2 80  ? 49.01600 11.18600  28.81100  1.000 32.63831  ? 78  LEU L CA   1 
ATOM   4403 C C    . LEU B 2 80  ? 50.40700 11.23500  28.19100  1.000 32.45803  ? 78  LEU L C    1 
ATOM   4404 O O    . LEU B 2 80  ? 50.94600 12.31300  27.92800  1.000 32.70805  ? 78  LEU L O    1 
ATOM   4405 C CB   . LEU B 2 80  ? 47.96000 11.52000  27.75800  1.000 30.56765  ? 78  LEU L CB   1 
ATOM   4406 C CG   . LEU B 2 80  ? 47.84200 10.56900  26.57000  1.000 32.65906  ? 78  LEU L CG   1 
ATOM   4407 C CD1  . LEU B 2 80  ? 47.25500 9.24800   27.01200  1.000 28.13686  ? 78  LEU L CD1  1 
ATOM   4408 C CD2  . LEU B 2 80  ? 46.99600 11.20100  25.48000  1.000 33.45901  ? 78  LEU L CD2  1 
ATOM   4409 H H    . LEU B 2 80  ? 48.33700 12.75400  29.79200  1.000 39.07251  ? 78  LEU L H    1 
ATOM   4410 H HA   . LEU B 2 80  ? 48.87000 10.28300  29.13400  1.000 39.16954  ? 78  LEU L HA   1 
ATOM   4411 H HB2  . LEU B 2 80  ? 47.09500 11.53300  28.19700  1.000 36.68476  ? 78  LEU L HB2  1 
ATOM   4412 H HB3  . LEU B 2 80  ? 48.16400 12.39700  27.39900  1.000 36.68476  ? 78  LEU L HB3  1 
ATOM   4413 H HG   . LEU B 2 80  ? 48.72200 10.39500  26.20300  1.000 39.19444  ? 78  LEU L HG   1 
ATOM   4414 H HD11 . LEU B 2 80  ? 47.15900 8.67000   26.23900  1.000 33.76781  ? 78  LEU L HD11 1 
ATOM   4415 H HD12 . LEU B 2 80  ? 47.85100 8.83800   27.65900  1.000 33.76781  ? 78  LEU L HD12 1 
ATOM   4416 H HD13 . LEU B 2 80  ? 46.38700 9.40700   27.41600  1.000 33.76781  ? 78  LEU L HD13 1 
ATOM   4417 H HD21 . LEU B 2 80  ? 46.91700 10.57900  24.74100  1.000 40.15439  ? 78  LEU L HD21 1 
ATOM   4418 H HD22 . LEU B 2 80  ? 46.11800 11.40200  25.83900  1.000 40.15439  ? 78  LEU L HD22 1 
ATOM   4419 H HD23 . LEU B 2 80  ? 47.42600 12.01800  25.18100  1.000 40.15439  ? 78  LEU L HD23 1 
ATOM   4420 N N    . GLN B 2 81  ? 50.98400 10.05600  27.94700  1.000 30.14699  ? 79  GLN L N    1 
ATOM   4421 C CA   . GLN B 2 81  ? 52.28600 9.93000   27.30700  1.000 30.77727  ? 79  GLN L CA   1 
ATOM   4422 C C    . GLN B 2 81  ? 52.15000 9.21700   25.96500  1.000 31.47827  ? 79  GLN L C    1 
ATOM   4423 O O    . GLN B 2 81  ? 51.22700 8.41800   25.77700  1.000 27.25609  ? 79  GLN L O    1 
ATOM   4424 C CB   . GLN B 2 81  ? 53.26800 9.15300   28.19300  1.000 30.99743  ? 79  GLN L CB   1 
ATOM   4425 C CG   . GLN B 2 81  ? 53.52600 9.79200   29.54400  1.000 33.15792  ? 79  GLN L CG   1 
ATOM   4426 C CD   . GLN B 2 81  ? 54.06700 11.20200  29.42600  1.000 39.31902  ? 79  GLN L CD   1 
ATOM   4427 O OE1  . GLN B 2 81  ? 53.44000 12.15900  29.88300  1.000 43.94939  ? 79  GLN L OE1  1 
ATOM   4428 N NE2  . GLN B 2 81  ? 55.23500 11.33900  28.80900  1.000 34.57778  ? 79  GLN L NE2  1 
ATOM   4429 H H    . GLN B 2 81  ? 50.62900 9.30000   28.14900  1.000 36.17996  ? 79  GLN L H    1 
ATOM   4430 H HA   . GLN B 2 81  ? 52.65400 10.81400  27.15100  1.000 36.93629  ? 79  GLN L HA   1 
ATOM   4431 H HB2  . GLN B 2 81  ? 52.90800 8.26600   28.35100  1.000 37.20048  ? 79  GLN L HB2  1 
ATOM   4432 H HB3  . GLN B 2 81  ? 54.11800 9.08800   27.73100  1.000 37.20048  ? 79  GLN L HB3  1 
ATOM   4433 H HG2  . GLN B 2 81  ? 52.69400 9.82900   30.04100  1.000 39.79308  ? 79  GLN L HG2  1 
ATOM   4434 H HG3  . GLN B 2 81  ? 54.17700 9.25900   30.02800  1.000 39.79308  ? 79  GLN L HG3  1 
ATOM   4435 H HE21 . GLN B 2 81  ? 55.64300 10.64600  28.50200  1.000 41.49691  ? 79  GLN L HE21 1 
ATOM   4436 H HE22 . GLN B 2 81  ? 55.58400 12.11900  28.71600  1.000 41.49691  ? 79  GLN L HE22 1 
ATOM   4437 N N    . PRO B 2 82  ? 53.05600 9.47500   25.01500  1.000 32.26781  ? 80  PRO L N    1 
ATOM   4438 C CA   . PRO B 2 82  ? 52.91200 8.85900   23.68300  1.000 30.47788  ? 80  PRO L CA   1 
ATOM   4439 C C    . PRO B 2 82  ? 52.81400 7.34500   23.72400  1.000 29.68867  ? 80  PRO L C    1 
ATOM   4440 O O    . PRO B 2 82  ? 52.10000 6.75200   22.90400  1.000 28.74806  ? 80  PRO L O    1 
ATOM   4441 C CB   . PRO B 2 82  ? 54.17600 9.31900   22.94100  1.000 29.80725  ? 80  PRO L CB   1 
ATOM   4442 C CG   . PRO B 2 82  ? 54.60500 10.56600  23.65100  1.000 31.19849  ? 80  PRO L CG   1 
ATOM   4443 C CD   . PRO B 2 82  ? 54.23500 10.36000  25.09400  1.000 32.77770  ? 80  PRO L CD   1 
ATOM   4444 H HA   . PRO B 2 82  ? 52.12900 9.22000   23.24000  1.000 36.57703  ? 80  PRO L HA   1 
ATOM   4445 H HB2  . PRO B 2 82  ? 54.86100 8.63400   22.99800  1.000 35.77227  ? 80  PRO L HB2  1 
ATOM   4446 H HB3  . PRO B 2 82  ? 53.96700 9.50200   22.01200  1.000 35.77227  ? 80  PRO L HB3  1 
ATOM   4447 H HG2  . PRO B 2 82  ? 55.56300 10.68500  23.55500  1.000 37.44176  ? 80  PRO L HG2  1 
ATOM   4448 H HG3  . PRO B 2 82  ? 54.13700 11.33100  23.28100  1.000 37.44176  ? 80  PRO L HG3  1 
ATOM   4449 H HD2  . PRO B 2 82  ? 54.95800 9.93100   25.57900  1.000 39.33681  ? 80  PRO L HD2  1 
ATOM   4450 H HD3  . PRO B 2 82  ? 54.00700 11.20300  25.51700  1.000 39.33681  ? 80  PRO L HD3  1 
ATOM   4451 N N    . GLU B 2 83  ? 53.51500 6.70000   24.65600  1.000 29.48750  ? 81  GLU L N    1 
ATOM   4452 C CA   . GLU B 2 83  ? 53.46600 5.24900   24.76000  1.000 30.35843  ? 81  GLU L CA   1 
ATOM   4453 C C    . GLU B 2 83  ? 52.13000 4.74000   25.28500  1.000 30.95009  ? 81  GLU L C    1 
ATOM   4454 O O    . GLU B 2 83  ? 51.92300 3.52000   25.31800  1.000 27.90782  ? 81  GLU L O    1 
ATOM   4455 C CB   . GLU B 2 83  ? 54.59700 4.75100   25.66300  1.000 31.18755  ? 81  GLU L CB   1 
ATOM   4456 C CG   . GLU B 2 83  ? 54.55700 5.28100   27.09600  1.000 37.14913  ? 81  GLU L CG   1 
ATOM   4457 C CD   . GLU B 2 83  ? 55.27900 6.61200   27.26400  1.000 38.79850  ? 81  GLU L CD   1 
ATOM   4458 O OE1  . GLU B 2 83  ? 55.58300 7.27100   26.24500  1.000 36.74924  ? 81  GLU L OE1  1 
ATOM   4459 O OE2  . GLU B 2 83  ? 55.54400 6.99700   28.42300  1.000 44.46895  ? 81  GLU L OE2  1 
ATOM   4460 H H    . GLU B 2 83  ? 54.02400 7.08000   25.23600  1.000 35.38857  ? 81  GLU L H    1 
ATOM   4461 H HA   . GLU B 2 83  ? 53.60000 4.87200   23.87600  1.000 36.43369  ? 81  GLU L HA   1 
ATOM   4462 H HB2  . GLU B 2 83  ? 54.55100 3.78300   25.70900  1.000 37.42863  ? 81  GLU L HB2  1 
ATOM   4463 H HB3  . GLU B 2 83  ? 55.44300 5.02400   25.27500  1.000 37.42863  ? 81  GLU L HB3  1 
ATOM   4464 H HG2  . GLU B 2 83  ? 53.63200 5.40800   27.35800  1.000 44.58253  ? 81  GLU L HG2  1 
ATOM   4465 H HG3  . GLU B 2 83  ? 54.98200 4.63500   27.68200  1.000 44.58253  ? 81  GLU L HG3  1 
ATOM   4466 N N    . ASP B 2 84  ? 51.22700 5.63200   25.69300  1.000 26.68660  ? 82  ASP L N    1 
ATOM   4467 C CA   . ASP B 2 84  ? 49.92000 5.22300   26.19000  1.000 27.50857  ? 82  ASP L CA   1 
ATOM   4468 C C    . ASP B 2 84  ? 48.91300 4.98600   25.07600  1.000 26.45853  ? 82  ASP L C    1 
ATOM   4469 O O    . ASP B 2 84  ? 47.77800 4.59700   25.36700  1.000 25.51824  ? 82  ASP L O    1 
ATOM   4470 C CB   . ASP B 2 84  ? 49.36500 6.27200   27.15500  1.000 27.93827  ? 82  ASP L CB   1 
ATOM   4471 C CG   . ASP B 2 84  ? 50.22700 6.43800   28.38500  1.000 28.39724  ? 82  ASP L CG   1 
ATOM   4472 O OD1  . ASP B 2 84  ? 50.90900 5.46600   28.76900  1.000 29.60789  ? 82  ASP L OD1  1 
ATOM   4473 O OD2  . ASP B 2 84  ? 50.22000 7.54200   28.97000  1.000 32.99826  ? 82  ASP L OD2  1 
ATOM   4474 H H    . ASP B 2 84  ? 51.35200 6.48300   25.69200  1.000 32.02749  ? 82  ASP L H    1 
ATOM   4475 H HA   . ASP B 2 84  ? 50.02900 4.39400   26.68100  1.000 33.01385  ? 82  ASP L HA   1 
ATOM   4476 H HB2  . ASP B 2 84  ? 49.31900 7.12800   26.70200  1.000 33.52949  ? 82  ASP L HB2  1 
ATOM   4477 H HB3  . ASP B 2 84  ? 48.47900 6.00000   27.44300  1.000 33.52949  ? 82  ASP L HB3  1 
ATOM   4478 N N    . PHE B 2 85  ? 49.28800 5.23000   23.82000  1.000 23.22666  ? 83  PHE L N    1 
ATOM   4479 C CA   . PHE B 2 85  ? 48.42400 4.87000   22.70700  1.000 25.20844  ? 83  PHE L CA   1 
ATOM   4480 C C    . PHE B 2 85  ? 48.06200 3.39700   22.82300  1.000 21.39625  ? 83  PHE L C    1 
ATOM   4481 O O    . PHE B 2 85  ? 48.94100 2.54100   22.94700  1.000 22.02675  ? 83  PHE L O    1 
ATOM   4482 C CB   . PHE B 2 85  ? 49.12200 5.14300   21.37500  1.000 23.90747  ? 83  PHE L CB   1 
ATOM   4483 C CG   . PHE B 2 85  ? 48.34600 4.66500   20.18500  1.000 25.17783  ? 83  PHE L CG   1 
ATOM   4484 C CD1  . PHE B 2 85  ? 47.36500 5.45900   19.61700  1.000 26.52813  ? 83  PHE L CD1  1 
ATOM   4485 C CD2  . PHE B 2 85  ? 48.58900 3.41600   19.64000  1.000 26.77917  ? 83  PHE L CD2  1 
ATOM   4486 C CE1  . PHE B 2 85  ? 46.64300 5.01700   18.52200  1.000 28.63920  ? 83  PHE L CE1  1 
ATOM   4487 C CE2  . PHE B 2 85  ? 47.86900 2.97000   18.54800  1.000 26.92744  ? 83  PHE L CE2  1 
ATOM   4488 C CZ   . PHE B 2 85  ? 46.89500 3.77200   17.99000  1.000 26.72698  ? 83  PHE L CZ   1 
ATOM   4489 H H    . PHE B 2 85  ? 50.03000 5.59900   23.59200  1.000 27.87557  ? 83  PHE L H    1 
ATOM   4490 H HA   . PHE B 2 85  ? 47.61700 5.40800   22.72200  1.000 30.25370  ? 83  PHE L HA   1 
ATOM   4491 H HB2  . PHE B 2 85  ? 49.25200 6.09900   21.28100  1.000 28.69254  ? 83  PHE L HB2  1 
ATOM   4492 H HB3  . PHE B 2 85  ? 49.97900 4.68900   21.37300  1.000 28.69254  ? 83  PHE L HB3  1 
ATOM   4493 H HD1  . PHE B 2 85  ? 47.18800 6.29800   19.97500  1.000 31.83733  ? 83  PHE L HD1  1 
ATOM   4494 H HD2  . PHE B 2 85  ? 49.24400 2.87100   20.01300  1.000 32.13857  ? 83  PHE L HD2  1 
ATOM   4495 H HE1  . PHE B 2 85  ? 45.98900 5.56100   18.14600  1.000 34.37061  ? 83  PHE L HE1  1 
ATOM   4496 H HE2  . PHE B 2 85  ? 48.04200 2.13000   18.18800  1.000 32.31649  ? 83  PHE L HE2  1 
ATOM   4497 H HZ   . PHE B 2 85  ? 46.40800 3.47300   17.25700  1.000 32.07595  ? 83  PHE L HZ   1 
ATOM   4498 N N    . ALA B 2 86  ? 46.76400 3.11100   22.81800  1.000 21.67761  ? 84  ALA L N    1 
ATOM   4499 C CA   . ALA B 2 86  ? 46.27700 1.75400   23.02400  1.000 20.11799  ? 84  ALA L CA   1 
ATOM   4500 C C    . ALA B 2 86  ? 44.75700 1.79300   23.02800  1.000 19.42720  ? 84  ALA L C    1 
ATOM   4501 O O    . ALA B 2 86  ? 44.14000 2.86200   23.00900  1.000 19.77692  ? 84  ALA L O    1 
ATOM   4502 C CB   . ALA B 2 86  ? 46.79100 1.15000   24.33300  1.000 21.66830  ? 84  ALA L CB   1 
ATOM   4503 H H    . ALA B 2 86  ? 46.14200 3.69200   22.69700  1.000 26.01670  ? 84  ALA L H    1 
ATOM   4504 H HA   . ALA B 2 86  ? 46.57300 1.19900   22.28600  1.000 24.14515  ? 84  ALA L HA   1 
ATOM   4505 H HB1  . ALA B 2 86  ? 46.41100 0.26300   24.44200  1.000 26.00553  ? 84  ALA L HB1  1 
ATOM   4506 H HB2  . ALA B 2 86  ? 47.75800 1.09300   24.29700  1.000 26.00553  ? 84  ALA L HB2  1 
ATOM   4507 H HB3  . ALA B 2 86  ? 46.52000 1.71800   25.07100  1.000 26.00553  ? 84  ALA L HB3  1 
ATOM   4508 N N    . THR B 2 87  ? 44.16400 0.60500   23.03600  1.000 20.05871  ? 85  THR L N    1 
ATOM   4509 C CA   . THR B 2 87  ? 42.74700 0.42900   23.31400  1.000 17.68681  ? 85  THR L CA   1 
ATOM   4510 C C    . THR B 2 87  ? 42.61700 -0.08000  24.74200  1.000 18.79779  ? 85  THR L C    1 
ATOM   4511 O O    . THR B 2 87  ? 43.31400 -1.02200  25.13500  1.000 18.38826  ? 85  THR L O    1 
ATOM   4512 C CB   . THR B 2 87  ? 42.09900 -0.54800  22.33500  1.000 21.82901  ? 85  THR L CB   1 
ATOM   4513 O OG1  . THR B 2 87  ? 42.25200 -0.05100  21.00000  1.000 20.44749  ? 85  THR L OG1  1 
ATOM   4514 C CG2  . THR B 2 87  ? 40.61200 -0.71500  22.64900  1.000 20.63823  ? 85  THR L CG2  1 
ATOM   4515 H H    . THR B 2 87  ? 44.57500 -0.13400  22.87900  1.000 24.07402  ? 85  THR L H    1 
ATOM   4516 H HA   . THR B 2 87  ? 42.27800 1.27300   23.22300  1.000 21.22775  ? 85  THR L HA   1 
ATOM   4517 H HB   . THR B 2 87  ? 42.52400 -1.41600  22.40900  1.000 26.19838  ? 85  THR L HB   1 
ATOM   4518 H HG1  . THR B 2 87  ? 41.85200 -0.55300  20.45800  1.000 24.54056  ? 85  THR L HG1  1 
ATOM   4519 H HG21 . THR B 2 87  ? 40.20100 -1.30900  22.00100  1.000 24.76945  ? 85  THR L HG21 1 
ATOM   4520 H HG22 . THR B 2 87  ? 40.50100 -1.09200  23.53600  1.000 24.76945  ? 85  THR L HG22 1 
ATOM   4521 H HG23 . THR B 2 87  ? 40.16600 0.14500   22.61400  1.000 24.76945  ? 85  THR L HG23 1 
ATOM   4522 N N    . TYR B 2 88  ? 41.74100 0.55200   25.51400  1.000 18.06698  ? 86  TYR L N    1 
ATOM   4523 C CA   . TYR B 2 88  ? 41.55700 0.24700   26.92600  1.000 17.83795  ? 86  TYR L CA   1 
ATOM   4524 C C    . TYR B 2 88  ? 40.20100 -0.40800  27.13600  1.000 16.66702  ? 86  TYR L C    1 
ATOM   4525 O O    . TYR B 2 88  ? 39.19000 0.07000   26.61100  1.000 17.97750  ? 86  TYR L O    1 
ATOM   4526 C CB   . TYR B 2 88  ? 41.67800 1.52200   27.76400  1.000 16.92706  ? 86  TYR L CB   1 
ATOM   4527 C CG   . TYR B 2 88  ? 43.07200 2.10400   27.73800  1.000 17.59723  ? 86  TYR L CG   1 
ATOM   4528 C CD1  . TYR B 2 88  ? 43.48500 2.91800   26.69500  1.000 19.74892  ? 86  TYR L CD1  1 
ATOM   4529 C CD2  . TYR B 2 88  ? 43.98100 1.82400   28.74800  1.000 19.83907  ? 86  TYR L CD2  1 
ATOM   4530 C CE1  . TYR B 2 88  ? 44.75800 3.44000   26.65900  1.000 19.36798  ? 86  TYR L CE1  1 
ATOM   4531 C CE2  . TYR B 2 88  ? 45.26000 2.34500   28.71900  1.000 20.38878  ? 86  TYR L CE2  1 
ATOM   4532 C CZ   . TYR B 2 88  ? 45.64000 3.15300   27.67100  1.000 18.80578  ? 86  TYR L CZ   1 
ATOM   4533 O OH   . TYR B 2 88  ? 46.90800 3.67700   27.62600  1.000 22.99915  ? 86  TYR L OH   1 
ATOM   4534 H H    . TYR B 2 88  ? 41.22600 1.18000   25.23300  1.000 21.68394  ? 86  TYR L H    1 
ATOM   4535 H HA   . TYR B 2 88  ? 42.23500 -0.38100  27.22000  1.000 21.40911  ? 86  TYR L HA   1 
ATOM   4536 H HB2  . TYR B 2 88  ? 41.06700 2.19000   27.41500  1.000 20.31604  ? 86  TYR L HB2  1 
ATOM   4537 H HB3  . TYR B 2 88  ? 41.45500 1.31700   28.68600  1.000 20.31604  ? 86  TYR L HB3  1 
ATOM   4538 H HD1  . TYR B 2 88  ? 42.89100 3.11600   26.00800  1.000 23.70228  ? 86  TYR L HD1  1 
ATOM   4539 H HD2  . TYR B 2 88  ? 43.72500 1.27700   29.45500  1.000 23.81045  ? 86  TYR L HD2  1 
ATOM   4540 H HE1  . TYR B 2 88  ? 45.01900 3.98500   25.95200  1.000 23.24514  ? 86  TYR L HE1  1 
ATOM   4541 H HE2  . TYR B 2 88  ? 45.86100 2.15100   29.40300  1.000 24.47010  ? 86  TYR L HE2  1 
ATOM   4542 H HH   . TYR B 2 88  ? 47.02700 4.08100   26.89900  1.000 27.60255  ? 86  TYR L HH   1 
ATOM   4543 N N    . TYR B 2 89  ? 40.19000 -1.49700  27.91100  1.000 16.22706  ? 87  TYR L N    1 
ATOM   4544 C CA   . TYR B 2 89  ? 38.99600 -2.28500  28.17600  1.000 16.44679  ? 87  TYR L CA   1 
ATOM   4545 C C    . TYR B 2 89  ? 38.77700 -2.42500  29.67200  1.000 18.30696  ? 87  TYR L C    1 
ATOM   4546 O O    . TYR B 2 89  ? 39.71200 -2.76600  30.40300  1.000 17.10779  ? 87  TYR L O    1 
ATOM   4547 C CB   . TYR B 2 89  ? 39.11100 -3.70100  27.60000  1.000 17.53759  ? 87  TYR L CB   1 
ATOM   4548 C CG   . TYR B 2 89  ? 39.23400 -3.78500  26.10800  1.000 15.82533  ? 87  TYR L CG   1 
ATOM   4549 C CD1  . TYR B 2 89  ? 38.10800 -3.89500  25.31000  1.000 18.74794  ? 87  TYR L CD1  1 
ATOM   4550 C CD2  . TYR B 2 89  ? 40.47600 -3.77800  25.49500  1.000 20.56985  ? 87  TYR L CD2  1 
ATOM   4551 C CE1  . TYR B 2 89  ? 38.21600 -3.98100  23.93200  1.000 17.26646  ? 87  TYR L CE1  1 
ATOM   4552 C CE2  . TYR B 2 89  ? 40.59600 -3.86500  24.11700  1.000 17.80693  ? 87  TYR L CE2  1 
ATOM   4553 C CZ   . TYR B 2 89  ? 39.46200 -3.96700  23.34200  1.000 19.54746  ? 87  TYR L CZ   1 
ATOM   4554 O OH   . TYR B 2 89  ? 39.57000 -4.05100  21.97100  1.000 22.42913  ? 87  TYR L OH   1 
ATOM   4555 H H    . TYR B 2 89  ? 40.89000 -1.80500  28.30500  1.000 19.47604  ? 87  TYR L H    1 
ATOM   4556 H HA   . TYR B 2 89  ? 38.24600 -1.81700  27.77700  1.000 19.73972  ? 87  TYR L HA   1 
ATOM   4557 H HB2  . TYR B 2 89  ? 39.90000 -4.12100  27.97800  1.000 21.04868  ? 87  TYR L HB2  1 
ATOM   4558 H HB3  . TYR B 2 89  ? 38.31800 -4.19800  27.85300  1.000 21.04868  ? 87  TYR L HB3  1 
ATOM   4559 H HD1  . TYR B 2 89  ? 37.26700 -3.91000  25.70500  1.000 22.50109  ? 87  TYR L HD1  1 
ATOM   4560 H HD2  . TYR B 2 89  ? 41.24300 -3.71300  26.01700  1.000 24.68739  ? 87  TYR L HD2  1 
ATOM   4561 H HE1  . TYR B 2 89  ? 37.45100 -4.04800  23.40700  1.000 20.72332  ? 87  TYR L HE1  1 
ATOM   4562 H HE2  . TYR B 2 89  ? 41.43600 -3.85500  23.71900  1.000 21.37189  ? 87  TYR L HE2  1 
ATOM   4563 H HH   . TYR B 2 89  ? 40.36700 -3.92400  21.73700  1.000 26.91852  ? 87  TYR L HH   1 
ATOM   4564 N N    . CYS B 2 90  ? 37.54200 -2.21300  30.11900  1.000 19.09771  ? 88  CYS L N    1 
ATOM   4565 C CA   . CYS B 2 90  ? 37.12400 -2.66900  31.43600  1.000 20.12704  ? 88  CYS L CA   1 
ATOM   4566 C C    . CYS B 2 90  ? 36.59900 -4.09500  31.32400  1.000 22.00859  ? 88  CYS L C    1 
ATOM   4567 O O    . CYS B 2 90  ? 36.09100 -4.51200  30.27900  1.000 20.42888  ? 88  CYS L O    1 
ATOM   4568 C CB   . CYS B 2 90  ? 36.05100 -1.76100  32.04600  1.000 23.08824  ? 88  CYS L CB   1 
ATOM   4569 S SG   . CYS B 2 90  ? 34.49600 -1.55800  31.12800  1.000 28.57935  ? 88  CYS L SG   1 
ATOM   4570 H H    . CYS B 2 90  ? 36.92800 -1.80600  29.67500  1.000 22.92082  ? 88  CYS L H    1 
ATOM   4571 H HA   . CYS B 2 90  ? 37.88200 -2.64600  32.04100  1.000 24.15601  ? 88  CYS L HA   1 
ATOM   4572 H HB2  . CYS B 2 90  ? 35.81700 -2.12300  32.91500  1.000 27.70946  ? 88  CYS L HB2  1 
ATOM   4573 H HB3  . CYS B 2 90  ? 36.43400 -0.87600  32.14700  1.000 27.70946  ? 88  CYS L HB3  1 
ATOM   4574 N N    . VAL B 2 91  ? 36.74700 -4.85000  32.40600  1.000 20.26792  ? 89  VAL L N    1 
ATOM   4575 C CA   . VAL B 2 91  ? 36.26700 -6.22500  32.47200  1.000 18.77563  ? 89  VAL L CA   1 
ATOM   4576 C C    . VAL B 2 91  ? 35.76700 -6.46700  33.88700  1.000 22.52900  ? 89  VAL L C    1 
ATOM   4577 O O    . VAL B 2 91  ? 36.47100 -6.17700  34.86100  1.000 20.56719  ? 89  VAL L O    1 
ATOM   4578 C CB   . VAL B 2 91  ? 37.35900 -7.24000  32.07700  1.000 22.02892  ? 89  VAL L CB   1 
ATOM   4579 C CG1  . VAL B 2 91  ? 38.57900 -7.08400  32.95200  1.000 20.50871  ? 89  VAL L CG1  1 
ATOM   4580 C CG2  . VAL B 2 91  ? 36.82700 -8.67000  32.14100  1.000 21.20880  ? 89  VAL L CG2  1 
ATOM   4581 H H    . VAL B 2 91  ? 37.13000 -4.58300  33.12800  1.000 24.32508  ? 89  VAL L H    1 
ATOM   4582 H HA   . VAL B 2 91  ? 35.52500 -6.34800  31.86100  1.000 22.53433  ? 89  VAL L HA   1 
ATOM   4583 H HB   . VAL B 2 91  ? 37.62200 -7.06200  31.16000  1.000 26.43828  ? 89  VAL L HB   1 
ATOM   4584 H HG11 . VAL B 2 91  ? 39.28200 -7.66300  32.61900  1.000 24.61402  ? 89  VAL L HG11 1 
ATOM   4585 H HG12 . VAL B 2 91  ? 38.87100 -6.16000  32.92500  1.000 24.61402  ? 89  VAL L HG12 1 
ATOM   4586 H HG13 . VAL B 2 91  ? 38.34900 -7.33200  33.86100  1.000 24.61402  ? 89  VAL L HG13 1 
ATOM   4587 H HG21 . VAL B 2 91  ? 37.50700 -9.27500  31.80600  1.000 25.45413  ? 89  VAL L HG21 1 
ATOM   4588 H HG22 . VAL B 2 91  ? 36.61500 -8.88700  33.06200  1.000 25.45413  ? 89  VAL L HG22 1 
ATOM   4589 H HG23 . VAL B 2 91  ? 36.02900 -8.73500  31.59400  1.000 25.45413  ? 89  VAL L HG23 1 
ATOM   4590 N N    . GLY B 2 92  ? 34.54100 -6.96600  33.99500  1.000 21.97713  ? 90  GLY L N    1 
ATOM   4591 C CA   . GLY B 2 92  ? 33.93400 -7.25000  35.27400  1.000 23.45764  ? 90  GLY L CA   1 
ATOM   4592 C C    . GLY B 2 92  ? 33.65600 -8.72700  35.44400  1.000 25.33940  ? 90  GLY L C    1 
ATOM   4593 O O    . GLY B 2 92  ? 33.53600 -9.46700  34.46100  1.000 22.34614  ? 90  GLY L O    1 
ATOM   4594 H H    . GLY B 2 92  ? 34.03400 -7.15000  33.32500  1.000 26.37613  ? 90  GLY L H    1 
ATOM   4595 H HA2  . GLY B 2 92  ? 34.52900 -6.96400  35.98500  1.000 28.15273  ? 90  GLY L HA2  1 
ATOM   4596 H HA3  . GLY B 2 92  ? 33.09600 -6.76700  35.35000  1.000 28.15273  ? 90  GLY L HA3  1 
ATOM   4597 N N    . HIS B 2 93  ? 33.56700 -9.16100  36.69700  1.000 20.85548  ? 91  HIS L N    1 
ATOM   4598 C CA   . HIS B 2 93  ? 33.21900 -10.52600 37.06300  1.000 22.56602  ? 91  HIS L CA   1 
ATOM   4599 C C    . HIS B 2 93  ? 31.87400 -10.50400 37.77400  1.000 25.61834  ? 91  HIS L C    1 
ATOM   4600 O O    . HIS B 2 93  ? 31.61100 -9.61500  38.59100  1.000 24.75830  ? 91  HIS L O    1 
ATOM   4601 C CB   . HIS B 2 93  ? 34.29800 -11.13300 37.96000  1.000 24.59858  ? 91  HIS L CB   1 
ATOM   4602 C CG   . HIS B 2 93  ? 34.05600 -12.56500 38.32500  1.000 23.32585  ? 91  HIS L CG   1 
ATOM   4603 N ND1  . HIS B 2 93  ? 33.78900 -13.54000 37.38900  1.000 27.87005  ? 91  HIS L ND1  1 
ATOM   4604 C CD2  . HIS B 2 93  ? 34.06500 -13.19000 39.52600  1.000 28.30900  ? 91  HIS L CD2  1 
ATOM   4605 C CE1  . HIS B 2 93  ? 33.63400 -14.70200 37.99800  1.000 27.28776  ? 91  HIS L CE1  1 
ATOM   4606 N NE2  . HIS B 2 93  ? 33.79600 -14.51600 39.29500  1.000 29.67876  ? 91  HIS L NE2  1 
ATOM   4607 H H    . HIS B 2 93  ? 33.71100 -8.66000  37.38100  1.000 25.03015  ? 91  HIS L H    1 
ATOM   4608 H HA   . HIS B 2 93  ? 33.14300 -11.08900 36.27700  1.000 27.08279  ? 91  HIS L HA   1 
ATOM   4609 H HB2  . HIS B 2 93  ? 35.14900 -11.08800 37.49700  1.000 29.52186  ? 91  HIS L HB2  1 
ATOM   4610 H HB3  . HIS B 2 93  ? 34.34000 -10.62300 38.78400  1.000 29.52186  ? 91  HIS L HB3  1 
ATOM   4611 H HD1  . HIS B 2 93  ? 33.73200 -13.41200 36.54000  1.000 33.44763  ? 91  HIS L HD1  1 
ATOM   4612 H HD2  . HIS B 2 93  ? 34.22400 -12.79500 40.35300  1.000 33.97438  ? 91  HIS L HD2  1 
ATOM   4613 H HE1  . HIS B 2 93  ? 33.44300 -15.51200 37.58300  1.000 32.74889  ? 91  HIS L HE1  1 
ATOM   4614 N N    . TYR B 2 94  ? 31.01900 -11.47300 37.45000  1.000 24.65644  ? 92  TYR L N    1 
ATOM   4615 C CA   . TYR B 2 94  ? 29.64100 -11.46500 37.91400  1.000 26.09812  ? 92  TYR L CA   1 
ATOM   4616 C C    . TYR B 2 94  ? 29.21200 -12.87200 38.29800  1.000 29.40913  ? 92  TYR L C    1 
ATOM   4617 O O    . TYR B 2 94  ? 29.76400 -13.86300 37.81500  1.000 27.05662  ? 92  TYR L O    1 
ATOM   4618 C CB   . TYR B 2 94  ? 28.68400 -10.93900 36.83400  1.000 28.90909  ? 92  TYR L CB   1 
ATOM   4619 C CG   . TYR B 2 94  ? 29.07900 -9.61200  36.23700  1.000 26.80724  ? 92  TYR L CG   1 
ATOM   4620 C CD1  . TYR B 2 94  ? 30.07900 -9.52800  35.27700  1.000 27.96845  ? 92  TYR L CD1  1 
ATOM   4621 C CD2  . TYR B 2 94  ? 28.44000 -8.44400  36.62300  1.000 29.19883  ? 92  TYR L CD2  1 
ATOM   4622 C CE1  . TYR B 2 94  ? 30.44000 -8.31300  34.72700  1.000 28.17897  ? 92  TYR L CE1  1 
ATOM   4623 C CE2  . TYR B 2 94  ? 28.78900 -7.22900  36.07900  1.000 27.27782  ? 92  TYR L CE2  1 
ATOM   4624 C CZ   . TYR B 2 94  ? 29.78900 -7.16700  35.13100  1.000 28.91841  ? 92  TYR L CZ   1 
ATOM   4625 O OH   . TYR B 2 94  ? 30.13900 -5.95100  34.59400  1.000 32.58923  ? 92  TYR L OH   1 
ATOM   4626 H H    . TYR B 2 94  ? 31.21900 -12.14900 36.95800  1.000 29.59130  ? 92  TYR L H    1 
ATOM   4627 H HA   . TYR B 2 94  ? 29.58900 -10.89800 38.70000  1.000 31.32132  ? 92  TYR L HA   1 
ATOM   4628 H HB2  . TYR B 2 94  ? 28.64900 -11.58600 36.11200  1.000 34.69447  ? 92  TYR L HB2  1 
ATOM   4629 H HB3  . TYR B 2 94  ? 27.80400 -10.83300 37.22700  1.000 34.69447  ? 92  TYR L HB3  1 
ATOM   4630 H HD1  . TYR B 2 94  ? 30.51300 -10.30200 34.99900  1.000 33.56571  ? 92  TYR L HD1  1 
ATOM   4631 H HD2  . TYR B 2 94  ? 27.76400 -8.48200  37.26100  1.000 35.04216  ? 92  TYR L HD2  1 
ATOM   4632 H HE1  . TYR B 2 94  ? 31.11700 -8.26800  34.09100  1.000 33.81833  ? 92  TYR L HE1  1 
ATOM   4633 H HE2  . TYR B 2 94  ? 28.35300 -6.45300  36.34900  1.000 32.73696  ? 92  TYR L HE2  1 
ATOM   4634 H HH   . TYR B 2 94  ? 30.84000 -6.02900  34.13800  1.000 39.11065  ? 92  TYR L HH   1 
ATOM   4635 N N    . GLY B 2 95  ? 28.20500 -12.95000 39.16200  1.000 24.89533  ? 93  GLY L N    1 
ATOM   4636 C CA   . GLY B 2 95  ? 27.49600 -14.19000 39.36900  1.000 28.92621  ? 93  GLY L CA   1 
ATOM   4637 C C    . GLY B 2 95  ? 27.14700 -14.39500 40.82300  1.000 32.77876  ? 93  GLY L C    1 
ATOM   4638 O O    . GLY B 2 95  ? 27.04100 -13.44700 41.59900  1.000 29.06659  ? 93  GLY L O    1 
ATOM   4639 H H    . GLY B 2 95  ? 27.91900 -12.29200 39.63700  1.000 29.87796  ? 93  GLY L H    1 
ATOM   4640 H HA2  . GLY B 2 95  ? 26.67600 -14.18500 38.85300  1.000 34.71502  ? 93  GLY L HA2  1 
ATOM   4641 H HA3  . GLY B 2 95  ? 28.04900 -14.93200 39.07700  1.000 34.71502  ? 93  GLY L HA3  1 
ATOM   4642 N N    . SER B 2 96  ? 26.96100 -15.67000 41.16100  1.000 34.75840  ? 94  SER L N    1 
ATOM   4643 C CA   . SER B 2 96  ? 26.60900 -16.09700 42.50600  1.000 37.05904  ? 94  SER L CA   1 
ATOM   4644 C C    . SER B 2 96  ? 27.51000 -17.25300 42.92300  1.000 39.83941  ? 94  SER L C    1 
ATOM   4645 O O    . SER B 2 96  ? 28.51300 -17.53300 42.26000  1.000 36.28676  ? 94  SER L O    1 
ATOM   4646 C CB   . SER B 2 96  ? 25.14700 -16.52600 42.55900  1.000 36.33834  ? 94  SER L CB   1 
ATOM   4647 O OG   . SER B 2 96  ? 24.96700 -17.71900 41.81800  1.000 37.92816  ? 94  SER L OG   1 
ATOM   4648 H H    . SER B 2 96  ? 27.03500 -16.32500 40.60900  1.000 41.71365  ? 94  SER L H    1 
ATOM   4649 H HA   . SER B 2 96  ? 26.72700 -15.36300 43.12800  1.000 44.47442  ? 94  SER L HA   1 
ATOM   4650 H HB2  . SER B 2 96  ? 24.89200 -16.68100 43.48200  1.000 43.60957  ? 94  SER L HB2  1 
ATOM   4651 H HB3  . SER B 2 96  ? 24.59500 -15.82600 42.17600  1.000 43.60957  ? 94  SER L HB3  1 
ATOM   4652 H HG   . SER B 2 96  ? 24.20300 -18.03700 41.96500  1.000 45.51736  ? 94  SER L HG   1 
ATOM   4653 N N    . GLU B 2 97  ? 27.15700 -17.94600 44.00600  1.000 41.21846  ? 95  GLU L N    1 
ATOM   4654 C CA   . GLU B 2 97  ? 27.96600 -19.07900 44.43700  1.000 41.95786  ? 95  GLU L CA   1 
ATOM   4655 C C    . GLU B 2 97  ? 27.89000 -20.25000 43.46500  1.000 41.25749  ? 95  GLU L C    1 
ATOM   4656 O O    . GLU B 2 97  ? 28.75900 -21.12700 43.50500  1.000 43.56811  ? 95  GLU L O    1 
ATOM   4657 C CB   . GLU B 2 97  ? 27.53800 -19.52800 45.83500  1.000 49.45853  ? 95  GLU L CB   1 
ATOM   4658 C CG   . GLU B 2 97  ? 27.91100 -18.54300 46.93600  1.000 54.59809  ? 95  GLU L CG   1 
ATOM   4659 C CD   . GLU B 2 97  ? 27.41400 -18.97500 48.30300  1.000 68.89800  ? 95  GLU L CD   1 
ATOM   4660 O OE1  . GLU B 2 97  ? 26.72500 -20.01400 48.38600  1.000 65.02737  ? 95  GLU L OE1  1 
ATOM   4661 O OE2  . GLU B 2 97  ? 27.71100 -18.27500 49.29500  1.000 70.38805  ? 95  GLU L OE2  1 
ATOM   4662 H H    . GLU B 2 97  ? 26.46900 -17.78400 44.49500  1.000 49.46572  ? 95  GLU L H    1 
ATOM   4663 H HA   . GLU B 2 97  ? 28.89300 -18.79800 44.48700  1.000 50.35300  ? 95  GLU L HA   1 
ATOM   4664 H HB2  . GLU B 2 97  ? 26.57400 -19.63400 45.84700  1.000 59.35381  ? 95  GLU L HB2  1 
ATOM   4665 H HB3  . GLU B 2 97  ? 27.96700 -20.37400 46.03600  1.000 59.35381  ? 95  GLU L HB3  1 
ATOM   4666 H HG2  . GLU B 2 97  ? 28.87700 -18.46800 46.97800  1.000 65.52128  ? 95  GLU L HG2  1 
ATOM   4667 H HG3  . GLU B 2 97  ? 27.51900 -17.68000 46.73300  1.000 65.52128  ? 95  GLU L HG3  1 
ATOM   4668 N N    . ASN B 2 98  A 26.88300 -20.27800 42.58700  1.000 39.75647  ? 95  ASN L N    1 
ATOM   4669 C CA   . ASN B 2 98  A 26.69400 -21.36700 41.63600  1.000 43.16896  ? 95  ASN L CA   1 
ATOM   4670 C C    . ASN B 2 98  A 26.58000 -20.85100 40.20400  1.000 40.45837  ? 95  ASN L C    1 
ATOM   4671 O O    . ASN B 2 98  A 25.97300 -21.50400 39.35000  1.000 40.15837  ? 95  ASN L O    1 
ATOM   4672 C CB   . ASN B 2 98  A 25.45800 -22.19000 42.00100  1.000 44.11886  ? 95  ASN L CB   1 
ATOM   4673 C CG   . ASN B 2 98  A 25.54300 -22.77600 43.39400  1.000 44.49920  ? 95  ASN L CG   1 
ATOM   4674 O OD1  . ASN B 2 98  A 26.62700 -23.10200 43.87700  1.000 45.26988  ? 95  ASN L OD1  1 
ATOM   4675 N ND2  . ASN B 2 98  A 24.39600 -22.91100 44.04900  1.000 44.70983  ? 95  ASN L ND2  1 
ATOM   4676 H H    . ASN B 2 98  A 26.28500 -19.66200 42.52400  1.000 47.71133  ? 95  ASN L H    1 
ATOM   4677 H HA   . ASN B 2 98  A 27.47200 -21.94500 41.67500  1.000 51.80632  ? 95  ASN L HA   1 
ATOM   4678 H HB2  . ASN B 2 98  A 24.67500 -21.61900 41.96100  1.000 52.94621  ? 95  ASN L HB2  1 
ATOM   4679 H HB3  . ASN B 2 98  A 25.36800 -22.92200 41.37100  1.000 52.94621  ? 95  ASN L HB3  1 
ATOM   4680 H HD21 . ASN B 2 98  A 24.39200 -23.23900 44.84400  1.000 53.65537  ? 95  ASN L HD21 1 
ATOM   4681 H HD22 . ASN B 2 98  A 23.65800 -22.67000 43.67900  1.000 53.65537  ? 95  ASN L HD22 1 
ATOM   4682 N N    . ASP B 2 99  B 27.15300 -19.68100 39.92900  1.000 38.34779  ? 95  ASP L N    1 
ATOM   4683 C CA   . ASP B 2 99  B 27.15900 -19.10800 38.58900  1.000 37.88738  ? 95  ASP L CA   1 
ATOM   4684 C C    . ASP B 2 99  B 28.26900 -18.07200 38.51500  1.000 37.90839  ? 95  ASP L C    1 
ATOM   4685 O O    . ASP B 2 99  B 28.43500 -17.27300 39.43900  1.000 33.99681  ? 95  ASP L O    1 
ATOM   4686 C CB   . ASP B 2 99  B 25.81600 -18.45700 38.23800  1.000 40.00832  ? 95  ASP L CB   1 
ATOM   4687 C CG   . ASP B 2 99  B 24.81700 -19.44500 37.67100  1.000 45.79935  ? 95  ASP L CG   1 
ATOM   4688 O OD1  . ASP B 2 99  B 25.16300 -20.15600 36.70300  1.000 48.74941  ? 95  ASP L OD1  1 
ATOM   4689 O OD2  . ASP B 2 99  B 23.68500 -19.51000 38.19500  1.000 47.33907  ? 95  ASP L OD2  1 
ATOM   4690 H H    . ASP B 2 99  B 27.55300 -19.19200 40.51300  1.000 46.02092  ? 95  ASP L H    1 
ATOM   4691 H HA   . ASP B 2 99  B 27.33200 -19.81000 37.94200  1.000 45.46843  ? 95  ASP L HA   1 
ATOM   4692 H HB2  . ASP B 2 99  B 25.43300 -18.07000 39.04000  1.000 48.01356  ? 95  ASP L HB2  1 
ATOM   4693 H HB3  . ASP B 2 99  B 25.96400 -17.76600 37.57400  1.000 48.01356  ? 95  ASP L HB3  1 
ATOM   4694 N N    . ALA B 2 100 C 29.01700 -18.08300 37.41400  1.000 35.60774  ? 95  ALA L N    1 
ATOM   4695 C CA   . ALA B 2 100 C 30.14900 -17.18100 37.24500  1.000 32.85725  ? 95  ALA L CA   1 
ATOM   4696 C C    . ALA B 2 100 C 30.20200 -16.69500 35.80600  1.000 32.91811  ? 95  ALA L C    1 
ATOM   4697 O O    . ALA B 2 100 C 30.12600 -17.49800 34.87200  1.000 28.86522  ? 95  ALA L O    1 
ATOM   4698 C CB   . ALA B 2 100 C 31.46400 -17.87300 37.62000  1.000 33.51805  ? 95  ALA L CB   1 
ATOM   4699 H H    . ALA B 2 100 C 28.88700 -18.60900 36.74600  1.000 42.73286  ? 95  ALA L H    1 
ATOM   4700 H HA   . ALA B 2 100 C 30.03100 -16.40700 37.81700  1.000 39.43227  ? 95  ALA L HA   1 
ATOM   4701 H HB1  . ALA B 2 100 C 32.19800 -17.25500 37.47900  1.000 40.22523  ? 95  ALA L HB1  1 
ATOM   4702 H HB2  . ALA B 2 100 C 31.42700 -18.13600 38.55300  1.000 40.22523  ? 95  ALA L HB2  1 
ATOM   4703 H HB3  . ALA B 2 100 C 31.58000 -18.65700 37.06000  1.000 40.22523  ? 95  ALA L HB3  1 
ATOM   4704 N N    . TYR B 2 101 D 30.33700 -15.38100 35.63600  1.000 28.79651  ? 95  TYR L N    1 
ATOM   4705 C CA   . TYR B 2 101 D 30.37100 -14.76900 34.31800  1.000 28.01762  ? 95  TYR L CA   1 
ATOM   4706 C C    . TYR B 2 101 D 31.41600 -13.66300 34.30400  1.000 26.06815  ? 95  TYR L C    1 
ATOM   4707 O O    . TYR B 2 101 D 31.79300 -13.12400 35.34700  1.000 25.25765  ? 95  TYR L O    1 
ATOM   4708 C CB   . TYR B 2 101 D 29.00400 -14.19100 33.92700  1.000 29.19760  ? 95  TYR L CB   1 
ATOM   4709 C CG   . TYR B 2 101 D 27.85800 -15.15100 34.12500  1.000 34.74796  ? 95  TYR L CG   1 
ATOM   4710 C CD1  . TYR B 2 101 D 27.60700 -16.16400 33.20800  1.000 37.39883  ? 95  TYR L CD1  1 
ATOM   4711 C CD2  . TYR B 2 101 D 27.02300 -15.04300 35.22800  1.000 36.86804  ? 95  TYR L CD2  1 
ATOM   4712 C CE1  . TYR B 2 101 D 26.55800 -17.04500 33.39000  1.000 42.19733  ? 95  TYR L CE1  1 
ATOM   4713 C CE2  . TYR B 2 101 D 25.97300 -15.91700 35.41700  1.000 39.34835  ? 95  TYR L CE2  1 
ATOM   4714 C CZ   . TYR B 2 101 D 25.74600 -16.91700 34.49900  1.000 44.05776  ? 95  TYR L CZ   1 
ATOM   4715 O OH   . TYR B 2 101 D 24.69700 -17.78700 34.68800  1.000 52.82840  ? 95  TYR L OH   1 
ATOM   4716 H H    . TYR B 2 101 D 30.41200 -14.81800 36.28100  1.000 34.55939  ? 95  TYR L H    1 
ATOM   4717 H HA   . TYR B 2 101 D 30.62300 -15.43900 33.66300  1.000 33.62471  ? 95  TYR L HA   1 
ATOM   4718 H HB2  . TYR B 2 101 D 28.83000 -13.40700 34.47100  1.000 35.04069  ? 95  TYR L HB2  1 
ATOM   4719 H HB3  . TYR B 2 101 D 29.02600 -13.94600 32.98900  1.000 35.04069  ? 95  TYR L HB3  1 
ATOM   4720 H HD1  . TYR B 2 101 D 28.15500 -16.25100 32.46100  1.000 44.88217  ? 95  TYR L HD1  1 
ATOM   4721 H HD2  . TYR B 2 101 D 27.17400 -14.37000 35.85100  1.000 44.24522  ? 95  TYR L HD2  1 
ATOM   4722 H HE1  . TYR B 2 101 D 26.40000 -17.71900 32.76900  1.000 50.64037  ? 95  TYR L HE1  1 
ATOM   4723 H HE2  . TYR B 2 101 D 25.42200 -15.83100 36.16100  1.000 47.22159  ? 95  TYR L HE2  1 
ATOM   4724 H HH   . TYR B 2 101 D 24.84500 -18.27400 35.35600  1.000 63.39765  ? 95  TYR L HH   1 
ATOM   4725 N N    . TYR B 2 102 ? 31.88600 -13.33900 33.10100  1.000 23.94752  ? 96  TYR L N    1 
ATOM   4726 C CA   . TYR B 2 102 ? 32.70900 -12.16400 32.87000  1.000 22.10722  ? 96  TYR L CA   1 
ATOM   4727 C C    . TYR B 2 102 ? 32.17000 -11.41100 31.66300  1.000 22.62800  ? 96  TYR L C    1 
ATOM   4728 O O    . TYR B 2 102 ? 31.56800 -12.00400 30.76100  1.000 22.31739  ? 96  TYR L O    1 
ATOM   4729 C CB   . TYR B 2 102 ? 34.17000 -12.49800 32.58500  1.000 22.16780  ? 96  TYR L CB   1 
ATOM   4730 C CG   . TYR B 2 102 ? 34.99800 -13.01200 33.73200  1.000 22.41751  ? 96  TYR L CG   1 
ATOM   4731 C CD1  . TYR B 2 102 ? 35.00400 -14.35900 34.05500  1.000 23.55823  ? 96  TYR L CD1  1 
ATOM   4732 C CD2  . TYR B 2 102 ? 35.82500 -12.16200 34.45300  1.000 22.59774  ? 96  TYR L CD2  1 
ATOM   4733 C CE1  . TYR B 2 102 ? 35.78200 -14.84200 35.07900  1.000 23.83794  ? 96  TYR L CE1  1 
ATOM   4734 C CE2  . TYR B 2 102 ? 36.61300 -12.64000 35.48300  1.000 24.41906  ? 96  TYR L CE2  1 
ATOM   4735 C CZ   . TYR B 2 102 ? 36.58500 -13.98300 35.78900  1.000 23.94796  ? 96  TYR L CZ   1 
ATOM   4736 O OH   . TYR B 2 102 ? 37.35900 -14.48100 36.81000  1.000 25.80846  ? 96  TYR L OH   1 
ATOM   4737 H H    . TYR B 2 102 ? 31.73600 -13.79800 32.38900  1.000 28.74059  ? 96  TYR L H    1 
ATOM   4738 H HA   . TYR B 2 102 ? 32.67200 -11.61300 33.66700  1.000 26.53224  ? 96  TYR L HA   1 
ATOM   4739 H HB2  . TYR B 2 102 ? 34.19100 -13.18100 31.89600  1.000 26.60493  ? 96  TYR L HB2  1 
ATOM   4740 H HB3  . TYR B 2 102 ? 34.60400 -11.69200 32.26400  1.000 26.60493  ? 96  TYR L HB3  1 
ATOM   4741 H HD1  . TYR B 2 102 ? 34.47200 -14.94700 33.56800  1.000 28.27345  ? 96  TYR L HD1  1 
ATOM   4742 H HD2  . TYR B 2 102 ? 35.85000 -11.25700 34.23900  1.000 27.12086  ? 96  TYR L HD2  1 
ATOM   4743 H HE1  . TYR B 2 102 ? 35.76400 -15.74800 35.29100  1.000 28.60910  ? 96  TYR L HE1  1 
ATOM   4744 H HE2  . TYR B 2 102 ? 37.15700 -12.06000 35.96600  1.000 29.30645  ? 96  TYR L HE2  1 
ATOM   4745 H HH   . TYR B 2 102 ? 37.87600 -13.88400 37.09700  1.000 30.97372  ? 96  TYR L HH   1 
ATOM   4746 N N    . ALA B 2 103 ? 32.42200 -10.10700 31.62900  1.000 18.34560  ? 97  ALA L N    1 
ATOM   4747 C CA   . ALA B 2 103 ? 32.06200 -9.29600  30.47700  1.000 21.05767  ? 97  ALA L CA   1 
ATOM   4748 C C    . ALA B 2 103 ? 33.11700 -8.22800  30.25300  1.000 22.82025  ? 97  ALA L C    1 
ATOM   4749 O O    . ALA B 2 103 ? 33.62700 -7.63800  31.21000  1.000 20.92765  ? 97  ALA L O    1 
ATOM   4750 C CB   . ALA B 2 103 ? 30.68600 -8.64800  30.66000  1.000 22.18699  ? 97  ALA L CB   1 
ATOM   4751 H H    . ALA B 2 103 ? 32.80100 -9.66900  32.26400  1.000 22.01830  ? 97  ALA L H    1 
ATOM   4752 H HA   . ALA B 2 103 ? 32.03300 -9.85600  29.68500  1.000 25.27278  ? 97  ALA L HA   1 
ATOM   4753 H HB1  . ALA B 2 103 ? 30.48300 -8.11100  29.87700  1.000 26.62796  ? 97  ALA L HB1  1 
ATOM   4754 H HB2  . ALA B 2 103 ? 30.01900 -9.34500  30.76400  1.000 26.62796  ? 97  ALA L HB2  1 
ATOM   4755 H HB3  . ALA B 2 103 ? 30.70400 -8.08600  31.45000  1.000 26.62796  ? 97  ALA L HB3  1 
ATOM   4756 N N    . PHE B 2 104 ? 33.44500 -7.98900  28.98500  1.000 19.68762  ? 98  PHE L N    1 
ATOM   4757 C CA   . PHE B 2 104 ? 34.32500 -6.89800  28.59500  1.000 19.78748  ? 98  PHE L CA   1 
ATOM   4758 C C    . PHE B 2 104 ? 33.49300 -5.72100  28.10900  1.000 19.56724  ? 98  PHE L C    1 
ATOM   4759 O O    . PHE B 2 104 ? 32.49200 -5.90400  27.40700  1.000 16.68493  ? 98  PHE L O    1 
ATOM   4760 C CB   . PHE B 2 104 ? 35.28700 -7.32200  27.48200  1.000 21.69957  ? 98  PHE L CB   1 
ATOM   4761 C CG   . PHE B 2 104 ? 36.30500 -8.33300  27.90700  1.000 18.59724  ? 98  PHE L CG   1 
ATOM   4762 C CD1  . PHE B 2 104 ? 36.01000 -9.68300  27.87800  1.000 21.40918  ? 98  PHE L CD1  1 
ATOM   4763 C CD2  . PHE B 2 104 ? 37.56200 -7.93500  28.32200  1.000 16.55586  ? 98  PHE L CD2  1 
ATOM   4764 C CE1  . PHE B 2 104 ? 36.94800 -10.61800 28.26600  1.000 22.49018  ? 98  PHE L CE1  1 
ATOM   4765 C CE2  . PHE B 2 104 ? 38.50500 -8.86600  28.71000  1.000 17.25729  ? 98  PHE L CE2  1 
ATOM   4766 C CZ   . PHE B 2 104 ? 38.19800 -10.20800 28.68100  1.000 19.12796  ? 98  PHE L CZ   1 
ATOM   4767 H H    . PHE B 2 104 ? 33.16300 -8.45600  28.32100  1.000 23.62871  ? 98  PHE L H    1 
ATOM   4768 H HA   . PHE B 2 104 ? 34.85100 -6.62800  29.36400  1.000 23.74854  ? 98  PHE L HA   1 
ATOM   4769 H HB2  . PHE B 2 104 ? 34.77100 -7.71000  26.75700  1.000 26.04305  ? 98  PHE L HB2  1 
ATOM   4770 H HB3  . PHE B 2 104 ? 35.76300 -6.53800  27.16700  1.000 26.04305  ? 98  PHE L HB3  1 
ATOM   4771 H HD1  . PHE B 2 104 ? 35.17000 -9.96400  27.59500  1.000 25.69459  ? 98  PHE L HD1  1 
ATOM   4772 H HD2  . PHE B 2 104 ? 37.77600 -7.03000  28.34000  1.000 19.87060  ? 98  PHE L HD2  1 
ATOM   4773 H HE1  . PHE B 2 104 ? 36.73700 -11.52300 28.24800  1.000 26.99178  ? 98  PHE L HE1  1 
ATOM   4774 H HE2  . PHE B 2 104 ? 39.34600 -8.58700  28.99000  1.000 20.71232  ? 98  PHE L HE2  1 
ATOM   4775 H HZ   . PHE B 2 104 ? 38.83200 -10.83600 28.94100  1.000 22.95713  ? 98  PHE L HZ   1 
ATOM   4776 N N    . GLY B 2 105 ? 33.89900 -4.51900  28.49000  1.000 21.80810  ? 99  GLY L N    1 
ATOM   4777 C CA   . GLY B 2 105 ? 33.45000 -3.33200  27.78700  1.000 22.06786  ? 99  GLY L CA   1 
ATOM   4778 C C    . GLY B 2 105 ? 33.91100 -3.38000  26.34200  1.000 18.70561  ? 99  GLY L C    1 
ATOM   4779 O O    . GLY B 2 105 ? 34.76100 -4.17600  25.95300  1.000 17.64519  ? 99  GLY L O    1 
ATOM   4780 H H    . GLY B 2 105 ? 34.43000 -4.36600  29.14900  1.000 26.17329  ? 99  GLY L H    1 
ATOM   4781 H HA2  . GLY B 2 105 ? 32.48200 -3.28100  27.80800  1.000 26.48500  ? 99  GLY L HA2  1 
ATOM   4782 H HA3  . GLY B 2 105 ? 33.81800 -2.53900  28.20900  1.000 26.48500  ? 99  GLY L HA3  1 
ATOM   4783 N N    . GLN B 2 106 ? 33.32300 -2.50700  25.51500  1.000 20.51588  ? 100 GLN L N    1 
ATOM   4784 C CA   . GLN B 2 106 ? 33.61400 -2.56000  24.08700  1.000 21.24666  ? 100 GLN L CA   1 
ATOM   4785 C C    . GLN B 2 106 ? 34.98600 -1.99700  23.73700  1.000 22.73827  ? 100 GLN L C    1 
ATOM   4786 O O    . GLN B 2 106 ? 35.44600 -2.18700  22.60500  1.000 19.56730  ? 100 GLN L O    1 
ATOM   4787 C CB   . GLN B 2 106 ? 32.53100 -1.82800  23.28000  1.000 22.87699  ? 100 GLN L CB   1 
ATOM   4788 C CG   . GLN B 2 106 ? 32.69000 -0.32400  23.15600  1.000 27.22902  ? 100 GLN L CG   1 
ATOM   4789 C CD   . GLN B 2 106 ? 32.27700 0.42100   24.40400  1.000 29.74824  ? 100 GLN L CD   1 
ATOM   4790 O OE1  . GLN B 2 106 ? 31.95300 -0.18300  25.43000  1.000 26.05716  ? 100 GLN L OE1  1 
ATOM   4791 N NE2  . GLN B 2 106 ? 32.28200 1.74800   24.32400  1.000 32.74990  ? 100 GLN L NE2  1 
ATOM   4792 H H    . GLN B 2 106 ? 32.76900 -1.89400  25.75400  1.000 24.62263  ? 100 GLN L H    1 
ATOM   4793 H HA   . GLN B 2 106 ? 33.59600 -3.49000  23.81100  1.000 25.49956  ? 100 GLN L HA   1 
ATOM   4794 H HB2  . GLN B 2 106 ? 32.52800 -2.18900  22.38000  1.000 27.45596  ? 100 GLN L HB2  1 
ATOM   4795 H HB3  . GLN B 2 106 ? 31.67500 -1.99000  23.70600  1.000 27.45596  ? 100 GLN L HB3  1 
ATOM   4796 H HG2  . GLN B 2 106 ? 33.62100 -0.11900  22.98100  1.000 32.67840  ? 100 GLN L HG2  1 
ATOM   4797 H HG3  . GLN B 2 106 ? 32.13700 -0.00800  22.42400  1.000 32.67840  ? 100 GLN L HG3  1 
ATOM   4798 H HE21 . GLN B 2 106 ? 32.51200 2.13300   23.59000  1.000 39.30345  ? 100 GLN L HE21 1 
ATOM   4799 H HE22 . GLN B 2 106 ? 32.05600 2.22100   25.00600  1.000 39.30345  ? 100 GLN L HE22 1 
ATOM   4800 N N    . GLY B 2 107 ? 35.63800 -1.31800  24.66300  1.000 20.67732  ? 101 GLY L N    1 
ATOM   4801 C CA   . GLY B 2 107 ? 36.95300 -0.77200  24.40700  1.000 22.14903  ? 101 GLY L CA   1 
ATOM   4802 C C    . GLY B 2 107 ? 36.90100 0.70900   24.08900  1.000 21.27768  ? 101 GLY L C    1 
ATOM   4803 O O    . GLY B 2 107 ? 35.92400 1.22200   23.53000  1.000 23.08780  ? 101 GLY L O    1 
ATOM   4804 H H    . GLY B 2 107 ? 35.33700 -1.15900  25.45200  1.000 24.81636  ? 101 GLY L H    1 
ATOM   4805 H HA2  . GLY B 2 107 ? 37.51300 -0.89900  25.18900  1.000 26.58241  ? 101 GLY L HA2  1 
ATOM   4806 H HA3  . GLY B 2 107 ? 37.35400 -1.23400  23.65400  1.000 26.58241  ? 101 GLY L HA3  1 
ATOM   4807 N N    . THR B 2 108 ? 37.96500 1.41500   24.46600  1.000 19.72771  ? 102 THR L N    1 
ATOM   4808 C CA   . THR B 2 108 ? 38.11800 2.84100   24.20400  1.000 21.09684  ? 102 THR L CA   1 
ATOM   4809 C C    . THR B 2 108 ? 39.46400 3.04800   23.52800  1.000 20.73731  ? 102 THR L C    1 
ATOM   4810 O O    . THR B 2 108 ? 40.50500 2.77600   24.13500  1.000 18.47762  ? 102 THR L O    1 
ATOM   4811 C CB   . THR B 2 108 ? 38.04900 3.65900   25.50000  1.000 23.72939  ? 102 THR L CB   1 
ATOM   4812 O OG1  . THR B 2 108 ? 36.75900 3.50800   26.10800  1.000 21.92668  ? 102 THR L OG1  1 
ATOM   4813 C CG2  . THR B 2 108 ? 38.31400 5.13200   25.22400  1.000 24.41810  ? 102 THR L CG2  1 
ATOM   4814 H H    . THR B 2 108 ? 38.63300 1.07700   24.89000  1.000 23.67682  ? 102 THR L H    1 
ATOM   4815 H HA   . THR B 2 108 ? 37.41000 3.14400   23.61400  1.000 25.31977  ? 102 THR L HA   1 
ATOM   4816 H HB   . THR B 2 108 ? 38.72800 3.33800   26.11400  1.000 28.47884  ? 102 THR L HB   1 
ATOM   4817 H HG1  . THR B 2 108 ? 36.18000 3.91600   25.65700  1.000 26.31558  ? 102 THR L HG1  1 
ATOM   4818 H HG21 . THR B 2 108 ? 38.10000 5.66100   26.00900  1.000 29.30529  ? 102 THR L HG21 1 
ATOM   4819 H HG22 . THR B 2 108 ? 39.24800 5.26500   25.00000  1.000 29.30529  ? 102 THR L HG22 1 
ATOM   4820 H HG23 . THR B 2 108 ? 37.76600 5.43400   24.48200  1.000 29.30529  ? 102 THR L HG23 1 
ATOM   4821 N N    . LYS B 2 109 ? 39.45000 3.52100   22.28200  1.000 20.15655  ? 103 LYS L N    1 
ATOM   4822 C CA   . LYS B 2 109 ? 40.68700 3.80200   21.56200  1.000 20.66637  ? 103 LYS L CA   1 
ATOM   4823 C C    . LYS B 2 109 ? 41.21500 5.17500   21.96000  1.000 23.64772  ? 103 LYS L C    1 
ATOM   4824 O O    . LYS B 2 109 ? 40.52200 6.18200   21.78400  1.000 26.54889  ? 103 LYS L O    1 
ATOM   4825 C CB   . LYS B 2 109 ? 40.45900 3.75400   20.05400  1.000 24.68829  ? 103 LYS L CB   1 
ATOM   4826 C CG   . LYS B 2 109 ? 39.80700 2.48200   19.56700  1.000 26.55805  ? 103 LYS L CG   1 
ATOM   4827 C CD   . LYS B 2 109 ? 39.69400 2.45500   18.04900  1.000 31.83859  ? 103 LYS L CD   1 
ATOM   4828 C CE   . LYS B 2 109 ? 38.95400 1.20600   17.58100  1.000 38.76810  ? 103 LYS L CE   1 
ATOM   4829 N NZ   . LYS B 2 109 ? 39.48900 0.68100   16.29000  1.000 53.24825  ? 103 LYS L NZ   1 
ATOM   4830 H H    . LYS B 2 109 ? 38.73500 3.68800   21.83400  1.000 24.19143  ? 103 LYS L H    1 
ATOM   4831 H HA   . LYS B 2 109 ? 41.34300 3.12700   21.79900  1.000 24.80321  ? 103 LYS L HA   1 
ATOM   4832 H HB2  . LYS B 2 109 ? 39.88500 4.49500   19.80300  1.000 29.62952  ? 103 LYS L HB2  1 
ATOM   4833 H HB3  . LYS B 2 109 ? 41.31700 3.83500   19.60800  1.000 29.62952  ? 103 LYS L HB3  1 
ATOM   4834 H HG2  . LYS B 2 109 ? 40.34000 1.72100   19.84600  1.000 31.87323  ? 103 LYS L HG2  1 
ATOM   4835 H HG3  . LYS B 2 109 ? 38.91400 2.41600   19.94000  1.000 31.87323  ? 103 LYS L HG3  1 
ATOM   4836 H HD2  . LYS B 2 109 ? 39.20200 3.23400   17.74700  1.000 38.20987  ? 103 LYS L HD2  1 
ATOM   4837 H HD3  . LYS B 2 109 ? 40.58100 2.45100   17.65800  1.000 38.20987  ? 103 LYS L HD3  1 
ATOM   4838 H HE2  . LYS B 2 109 ? 39.04800 0.51200   18.25200  1.000 46.52530  ? 103 LYS L HE2  1 
ATOM   4839 H HE3  . LYS B 2 109 ? 38.01700 1.42100   17.45500  1.000 46.52530  ? 103 LYS L HE3  1 
ATOM   4840 H HZ1  . LYS B 2 109 ? 38.90400 0.83000   15.63600  1.000 63.90147  ? 103 LYS L HZ1  1 
ATOM   4841 H HZ2  . LYS B 2 109 ? 40.25600 1.08600   16.09100  1.000 63.90147  ? 103 LYS L HZ2  1 
ATOM   4842 H HZ3  . LYS B 2 109 ? 39.63300 -0.19500  16.35500  1.000 63.90147  ? 103 LYS L HZ3  1 
ATOM   4843 N N    . VAL B 2 110 ? 42.44300 5.22400   22.46700  1.000 21.72683  ? 104 VAL L N    1 
ATOM   4844 C CA   . VAL B 2 110 ? 43.08100 6.47500   22.86400  1.000 25.26829  ? 104 VAL L CA   1 
ATOM   4845 C C    . VAL B 2 110 ? 44.12700 6.82300   21.81200  1.000 25.49788  ? 104 VAL L C    1 
ATOM   4846 O O    . VAL B 2 110 ? 45.14400 6.13000   21.67700  1.000 25.68827  ? 104 VAL L O    1 
ATOM   4847 C CB   . VAL B 2 110 ? 43.70800 6.38200   24.26100  1.000 23.08753  ? 104 VAL L CB   1 
ATOM   4848 C CG1  . VAL B 2 110 ? 44.50300 7.64700   24.57100  1.000 27.74905  ? 104 VAL L CG1  1 
ATOM   4849 C CG2  . VAL B 2 110 ? 42.63000 6.15400   25.31900  1.000 23.15771  ? 104 VAL L CG2  1 
ATOM   4850 H H    . VAL B 2 110 ? 42.93600 4.53100   22.59400  1.000 26.07577  ? 104 VAL L H    1 
ATOM   4851 H HA   . VAL B 2 110 ? 42.41300 7.17900   22.87200  1.000 30.32552  ? 104 VAL L HA   1 
ATOM   4852 H HB   . VAL B 2 110 ? 44.31600 5.62700   24.28300  1.000 27.70860  ? 104 VAL L HB   1 
ATOM   4853 H HG11 . VAL B 2 110 ? 44.75600 7.64000   25.50700  1.000 33.30243  ? 104 VAL L HG11 1 
ATOM   4854 H HG12 . VAL B 2 110 ? 45.29700 7.66500   24.01400  1.000 33.30243  ? 104 VAL L HG12 1 
ATOM   4855 H HG13 . VAL B 2 110 ? 43.95000 8.42100   24.38400  1.000 33.30243  ? 104 VAL L HG13 1 
ATOM   4856 H HG21 . VAL B 2 110 ? 43.04800 6.12500   26.19400  1.000 27.79282  ? 104 VAL L HG21 1 
ATOM   4857 H HG22 . VAL B 2 110 ? 41.99100 6.88200   25.28000  1.000 27.79282  ? 104 VAL L HG22 1 
ATOM   4858 H HG23 . VAL B 2 110 ? 42.18400 5.31200   25.13800  1.000 27.79282  ? 104 VAL L HG23 1 
ATOM   4859 N N    . GLU B 2 111 ? 43.87900 7.90400   21.07600  1.000 25.81570  ? 105 GLU L N    1 
ATOM   4860 C CA   . GLU B 2 111 ? 44.78500 8.42000   20.06200  1.000 31.18873  ? 105 GLU L CA   1 
ATOM   4861 C C    . GLU B 2 111 ? 45.53300 9.63500   20.59900  1.000 30.06809  ? 105 GLU L C    1 
ATOM   4862 O O    . GLU B 2 111 ? 45.00400 10.40500  21.40600  1.000 30.73857  ? 105 GLU L O    1 
ATOM   4863 C CB   . GLU B 2 111 ? 44.01800 8.81000   18.79700  1.000 36.51848  ? 105 GLU L CB   1 
ATOM   4864 C CG   . GLU B 2 111 ? 42.92000 7.83600   18.39800  1.000 37.89806  ? 105 GLU L CG   1 
ATOM   4865 C CD   . GLU B 2 111 ? 42.09900 8.34500   17.22900  1.000 50.73835  ? 105 GLU L CD   1 
ATOM   4866 O OE1  . GLU B 2 111 ? 42.65800 8.46500   16.11800  1.000 49.31919  ? 105 GLU L OE1  1 
ATOM   4867 O OE2  . GLU B 2 111 ? 40.90100 8.64300   17.42500  1.000 52.60898  ? 105 GLU L OE2  1 
ATOM   4868 H H    . GLU B 2 111 ? 43.16200 8.37300   21.15200  1.000 30.98241  ? 105 GLU L H    1 
ATOM   4869 H HA   . GLU B 2 111 ? 45.43100 7.73500   19.82900  1.000 37.43005  ? 105 GLU L HA   1 
ATOM   4870 H HB2  . GLU B 2 111 ? 43.60400 9.67500   18.94100  1.000 43.82575  ? 105 GLU L HB2  1 
ATOM   4871 H HB3  . GLU B 2 111 ? 44.64600 8.86100   18.05900  1.000 43.82575  ? 105 GLU L HB3  1 
ATOM   4872 H HG2  . GLU B 2 111 ? 43.32200 6.99100   18.14000  1.000 45.48125  ? 105 GLU L HG2  1 
ATOM   4873 H HG3  . GLU B 2 111 ? 42.32300 7.70300   19.15100  1.000 45.48125  ? 105 GLU L HG3  1 
ATOM   4874 N N    . ILE B 2 112 ? 46.76700 9.80600   20.12900  1.000 29.27817  ? 106 ILE L N    1 
ATOM   4875 C CA   . ILE B 2 112 ? 47.65000 10.87800  20.57400  1.000 27.42736  ? 106 ILE L CA   1 
ATOM   4876 C C    . ILE B 2 112 ? 47.61400 11.99200  19.53700  1.000 29.69864  ? 106 ILE L C    1 
ATOM   4877 O O    . ILE B 2 112 ? 48.02900 11.79600  18.38900  1.000 28.43762  ? 106 ILE L O    1 
ATOM   4878 C CB   . ILE B 2 112 ? 49.09000 10.37400  20.77100  1.000 26.68685  ? 106 ILE L CB   1 
ATOM   4879 C CG1  . ILE B 2 112 ? 49.11500 9.09800   21.61600  1.000 30.90896  ? 106 ILE L CG1  1 
ATOM   4880 C CG2  . ILE B 2 112 ? 49.96200 11.45900  21.40100  1.000 29.32883  ? 106 ILE L CG2  1 
ATOM   4881 C CD1  . ILE B 2 112 ? 48.47500 9.23000   22.97500  1.000 30.62865  ? 106 ILE L CD1  1 
ATOM   4882 H H    . ILE B 2 112 ? 47.12400 9.29800   19.53400  1.000 35.13737  ? 106 ILE L H    1 
ATOM   4883 H HA   . ILE B 2 112 ? 47.32100 11.22600  21.41700  1.000 32.91641  ? 106 ILE L HA   1 
ATOM   4884 H HB   . ILE B 2 112 ? 49.45100 10.16100  19.89700  1.000 32.02780  ? 106 ILE L HB   1 
ATOM   4885 H HG12 . ILE B 2 112 ? 48.64100 8.40100   21.13700  1.000 37.09433  ? 106 ILE L HG12 1 
ATOM   4886 H HG13 . ILE B 2 112 ? 50.03900 8.83700   21.75300  1.000 37.09433  ? 106 ILE L HG13 1 
ATOM   4887 H HG21 . ILE B 2 112 ? 50.84700 11.09700  21.56500  1.000 35.19817  ? 106 ILE L HG21 1 
ATOM   4888 H HG22 . ILE B 2 112 ? 50.02100 12.21100  20.79100  1.000 35.19817  ? 106 ILE L HG22 1 
ATOM   4889 H HG23 . ILE B 2 112 ? 49.56000 11.74200  22.23700  1.000 35.19817  ? 106 ILE L HG23 1 
ATOM   4890 H HD11 . ILE B 2 112 ? 48.58300 8.39600   23.45800  1.000 36.75795  ? 106 ILE L HD11 1 
ATOM   4891 H HD12 . ILE B 2 112 ? 48.90700 9.95100   23.45900  1.000 36.75795  ? 106 ILE L HD12 1 
ATOM   4892 H HD13 . ILE B 2 112 ? 47.53100 9.42700   22.86200  1.000 36.75795  ? 106 ILE L HD13 1 
ATOM   4893 N N    . LYS B 2 113 ? 47.11600 13.15800  19.93500  1.000 29.66800  ? 107 LYS L N    1 
ATOM   4894 C CA   . LYS B 2 113 ? 47.23300 14.33900  19.09300  1.000 30.30836  ? 107 LYS L CA   1 
ATOM   4895 C C    . LYS B 2 113 ? 48.67600 14.82400  19.09700  1.000 29.75831  ? 107 LYS L C    1 
ATOM   4896 O O    . LYS B 2 113 ? 49.35600 14.79100  20.12600  1.000 31.49937  ? 107 LYS L O    1 
ATOM   4897 C CB   . LYS B 2 113 ? 46.31200 15.45200  19.58800  1.000 33.10912  ? 107 LYS L CB   1 
ATOM   4898 C CG   . LYS B 2 113 ? 45.05200 15.63300  18.76100  1.000 37.86846  ? 107 LYS L CG   1 
ATOM   4899 C CD   . LYS B 2 113 ? 44.66200 17.10000  18.65800  1.000 45.21855  ? 107 LYS L CD   1 
ATOM   4900 C CE   . LYS B 2 113 ? 44.17700 17.65000  19.98700  1.000 50.68865  ? 107 LYS L CE   1 
ATOM   4901 N NZ   . LYS B 2 113 ? 42.96900 16.92500  20.47300  1.000 46.55899  ? 107 LYS L NZ   1 
ATOM   4902 H H    . LYS B 2 113 ? 46.71000 13.29000  20.68200  1.000 35.60517  ? 107 LYS L H    1 
ATOM   4903 H HA   . LYS B 2 113 ? 46.97000 14.12000  18.18600  1.000 36.37361  ? 107 LYS L HA   1 
ATOM   4904 H HB2  . LYS B 2 113 ? 46.04100 15.24800  20.49700  1.000 39.73452  ? 107 LYS L HB2  1 
ATOM   4905 H HB3  . LYS B 2 113 ? 46.80000 16.29000  19.56800  1.000 39.73452  ? 107 LYS L HB3  1 
ATOM   4906 H HG2  . LYS B 2 113 ? 45.20400 15.29400  17.86500  1.000 45.44573  ? 107 LYS L HG2  1 
ATOM   4907 H HG3  . LYS B 2 113 ? 44.32100 15.15100  19.17900  1.000 45.44573  ? 107 LYS L HG3  1 
ATOM   4908 H HD2  . LYS B 2 113 ? 45.43300 17.61800  18.37800  1.000 54.26583  ? 107 LYS L HD2  1 
ATOM   4909 H HD3  . LYS B 2 113 ? 43.94500 17.19600  18.01000  1.000 54.26583  ? 107 LYS L HD3  1 
ATOM   4910 H HE2  . LYS B 2 113 ? 44.87800 17.55100  20.65000  1.000 60.82995  ? 107 LYS L HE2  1 
ATOM   4911 H HE3  . LYS B 2 113 ? 43.94800 18.58700  19.88300  1.000 60.82995  ? 107 LYS L HE3  1 
ATOM   4912 H HZ1  . LYS B 2 113 ? 42.39700 17.49800  20.84200  1.000 55.87436  ? 107 LYS L HZ1  1 
ATOM   4913 H HZ2  . LYS B 2 113 ? 42.56700 16.51200  19.79400  1.000 55.87436  ? 107 LYS L HZ2  1 
ATOM   4914 H HZ3  . LYS B 2 113 ? 43.20200 16.31800  21.08200  1.000 55.87436  ? 107 LYS L HZ3  1 
ATOM   4915 N N    . ARG B 2 114 ? 49.15100 15.26900  17.94000  1.000 30.55941  ? 108 ARG L N    1 
ATOM   4916 C CA   . ARG B 2 114 ? 50.48700 15.83900  17.86500  1.000 27.99796  ? 108 ARG L CA   1 
ATOM   4917 C C    . ARG B 2 114 ? 50.55800 16.78300  16.67300  1.000 26.64754  ? 108 ARG L C    1 
ATOM   4918 O O    . ARG B 2 114 ? 49.58600 16.97300  15.93600  1.000 28.35802  ? 108 ARG L O    1 
ATOM   4919 C CB   . ARG B 2 114 ? 51.55600 14.74300  17.78200  1.000 27.90851  ? 108 ARG L CB   1 
ATOM   4920 C CG   . ARG B 2 114 ? 51.43700 13.81300  16.57500  1.000 27.32795  ? 108 ARG L CG   1 
ATOM   4921 C CD   . ARG B 2 114 ? 52.81100 13.31400  16.13600  1.000 28.50937  ? 108 ARG L CD   1 
ATOM   4922 N NE   . ARG B 2 114 ? 53.58700 14.36700  15.49000  1.000 25.53702  ? 108 ARG L NE   1 
ATOM   4923 C CZ   . ARG B 2 114 ? 54.90400 14.34600  15.33200  1.000 25.10731  ? 108 ARG L CZ   1 
ATOM   4924 N NH1  . ARG B 2 114 ? 55.64200 13.35000  15.79700  1.000 26.10861  ? 108 ARG L NH1  1 
ATOM   4925 N NH2  . ARG B 2 114 ? 55.49800 15.35300  14.69700  1.000 28.54921  ? 108 ARG L NH2  1 
ATOM   4926 H H    . ARG B 2 114 ? 48.72300 15.25100  17.19500  1.000 36.67486  ? 108 ARG L H    1 
ATOM   4927 H HA   . ARG B 2 114 ? 50.64400 16.36100  18.66800  1.000 33.60112  ? 108 ARG L HA   1 
ATOM   4928 H HB2  . ARG B 2 114 ? 52.42700 15.16700  17.73800  1.000 33.49378  ? 108 ARG L HB2  1 
ATOM   4929 H HB3  . ARG B 2 114 ? 51.49400 14.19300  18.57900  1.000 33.49378  ? 108 ARG L HB3  1 
ATOM   4930 H HG2  . ARG B 2 114 ? 50.89200 13.04600  16.80900  1.000 32.79711  ? 108 ARG L HG2  1 
ATOM   4931 H HG3  . ARG B 2 114 ? 51.03400 14.29400  15.83500  1.000 32.79711  ? 108 ARG L HG3  1 
ATOM   4932 H HD2  . ARG B 2 114 ? 53.30300 13.00700  16.91400  1.000 34.21481  ? 108 ARG L HD2  1 
ATOM   4933 H HD3  . ARG B 2 114 ? 52.70000 12.58600  15.50500  1.000 34.21481  ? 108 ARG L HD3  1 
ATOM   4934 H HE   . ARG B 2 114 ? 53.16000 15.05000  15.18900  1.000 30.64800  ? 108 ARG L HE   1 
ATOM   4935 H HH11 . ARG B 2 114 ? 55.26900 12.69600  16.21200  1.000 31.33390  ? 108 ARG L HH11 1 
ATOM   4936 H HH12 . ARG B 2 114 ? 56.49400 13.35700  15.68300  1.000 31.33390  ? 108 ARG L HH12 1 
ATOM   4937 H HH21 . ARG B 2 114 ? 55.02800 16.00700  14.39500  1.000 34.26263  ? 108 ARG L HH21 1 
ATOM   4938 H HH22 . ARG B 2 114 ? 56.35100 15.35000  14.58900  1.000 34.26263  ? 108 ARG L HH22 1 
ATOM   4939 N N    . THR B 2 115 ? 51.73000 17.38400  16.50200  1.000 26.07668  ? 109 THR L N    1 
ATOM   4940 C CA   . THR B 2 115 ? 51.96000 18.31600  15.41700  1.000 27.99807  ? 109 THR L CA   1 
ATOM   4941 C C    . THR B 2 115 ? 51.99400 17.58100  14.08200  1.000 29.42910  ? 109 THR L C    1 
ATOM   4942 O O    . THR B 2 115 ? 52.28000 16.38400  14.00300  1.000 27.93778  ? 109 THR L O    1 
ATOM   4943 C CB   . THR B 2 115 ? 53.27600 19.05700  15.63500  1.000 29.36775  ? 109 THR L CB   1 
ATOM   4944 O OG1  . THR B 2 115 ? 54.34500 18.10700  15.70000  1.000 31.71715  ? 109 THR L OG1  1 
ATOM   4945 C CG2  . THR B 2 115 ? 53.24000 19.83900  16.93900  1.000 34.73868  ? 109 THR L CG2  1 
ATOM   4946 H H    . THR B 2 115 ? 52.41400 17.26500  17.01000  1.000 31.29558  ? 109 THR L H    1 
ATOM   4947 H HA   . THR B 2 115 ? 51.24200 18.96700  15.38700  1.000 33.60125  ? 109 THR L HA   1 
ATOM   4948 H HB   . THR B 2 115 ? 53.42200 19.67800  14.90400  1.000 35.24487  ? 109 THR L HB   1 
ATOM   4949 H HG1  . THR B 2 115 ? 55.03800 18.47400  15.99900  1.000 38.06415  ? 109 THR L HG1  1 
ATOM   4950 H HG21 . THR B 2 115 ? 54.10400 20.24600  17.10600  1.000 41.68998  ? 109 THR L HG21 1 
ATOM   4951 H HG22 . THR B 2 115 ? 52.56700 20.53600  16.89000  1.000 41.68998  ? 109 THR L HG22 1 
ATOM   4952 H HG23 . THR B 2 115 ? 53.02500 19.24500  17.67600  1.000 41.68998  ? 109 THR L HG23 1 
ATOM   4953 N N    . VAL B 2 116 ? 51.68800 18.32600  13.02100  1.000 27.53699  ? 110 VAL L N    1 
ATOM   4954 C CA   . VAL B 2 116 ? 51.73400 17.77400  11.67600  1.000 29.47877  ? 110 VAL L CA   1 
ATOM   4955 C C    . VAL B 2 116 ? 53.17600 17.44700  11.31400  1.000 29.00861  ? 110 VAL L C    1 
ATOM   4956 O O    . VAL B 2 116 ? 54.10700 18.18900  11.65400  1.000 27.57763  ? 110 VAL L O    1 
ATOM   4957 C CB   . VAL B 2 116 ? 51.11900 18.76900  10.67800  1.000 30.17895  ? 110 VAL L CB   1 
ATOM   4958 C CG1  . VAL B 2 116 ? 51.04900 18.16800  9.29400   1.000 29.54887  ? 110 VAL L CG1  1 
ATOM   4959 C CG2  . VAL B 2 116 ? 49.73500 19.19700  11.13800  1.000 35.65936  ? 110 VAL L CG2  1 
ATOM   4960 H H    . VAL B 2 116 ? 51.45200 19.15200  13.05600  1.000 33.04795  ? 110 VAL L H    1 
ATOM   4961 H HA   . VAL B 2 116 ? 51.21700 16.95300  11.64500  1.000 35.37809  ? 110 VAL L HA   1 
ATOM   4962 H HB   . VAL B 2 116 ? 51.68600 19.55500  10.63700  1.000 36.21831  ? 110 VAL L HB   1 
ATOM   4963 H HG11 . VAL B 2 116 ? 50.64100 18.81000  8.69100   1.000 35.46222  ? 110 VAL L HG11 1 
ATOM   4964 H HG12 . VAL B 2 116 ? 51.94700 17.95900  8.99500   1.000 35.46222  ? 110 VAL L HG12 1 
ATOM   4965 H HG13 . VAL B 2 116 ? 50.51400 17.35900  9.32700   1.000 35.46222  ? 110 VAL L HG13 1 
ATOM   4966 H HG21 . VAL B 2 116 ? 49.32100 19.72900  10.44000  1.000 42.79481  ? 110 VAL L HG21 1 
ATOM   4967 H HG22 . VAL B 2 116 ? 49.20100 18.40600  11.31100  1.000 42.79481  ? 110 VAL L HG22 1 
ATOM   4968 H HG23 . VAL B 2 116 ? 49.82000 19.72300  11.94800  1.000 42.79481  ? 110 VAL L HG23 1 
ATOM   4969 N N    . ALA B 2 117 ? 53.36900 16.32700  10.62600  1.000 27.97927  ? 111 ALA L N    1 
ATOM   4970 C CA   . ALA B 2 117 ? 54.69300 15.90900  10.18800  1.000 23.72750  ? 111 ALA L CA   1 
ATOM   4971 C C    . ALA B 2 117 ? 54.57200 15.35000  8.78100   1.000 25.12833  ? 111 ALA L C    1 
ATOM   4972 O O    . ALA B 2 117 ? 53.68500 14.53600  8.51100   1.000 23.36554  ? 111 ALA L O    1 
ATOM   4973 C CB   . ALA B 2 117 ? 55.29000 14.86300  11.13500  1.000 24.70857  ? 111 ALA L CB   1 
ATOM   4974 H H    . ALA B 2 117 ? 52.74100 15.78600  10.39900  1.000 33.57870  ? 111 ALA L H    1 
ATOM   4975 H HA   . ALA B 2 117 ? 55.29600 16.66800  10.17100  1.000 28.47657  ? 111 ALA L HA   1 
ATOM   4976 H HB1  . ALA B 2 117 ? 56.16400 14.60000  10.80500  1.000 29.65386  ? 111 ALA L HB1  1 
ATOM   4977 H HB2  . ALA B 2 117 ? 55.37400 15.25100  12.02100  1.000 29.65386  ? 111 ALA L HB2  1 
ATOM   4978 H HB3  . ALA B 2 117 ? 54.70200 14.09300  11.16600  1.000 29.65386  ? 111 ALA L HB3  1 
ATOM   4979 N N    . ALA B 2 118 ? 55.44800 15.80100  7.88800   1.000 22.38625  ? 112 ALA L N    1 
ATOM   4980 C CA   . ALA B 2 118 ? 55.39900 15.33900  6.51200   1.000 27.47975  ? 112 ALA L CA   1 
ATOM   4981 C C    . ALA B 2 118 ? 56.10800 13.99400  6.37400   1.000 24.00816  ? 112 ALA L C    1 
ATOM   4982 O O    . ALA B 2 118 ? 57.10600 13.73700  7.05200   1.000 22.22795  ? 112 ALA L O    1 
ATOM   4983 C CB   . ALA B 2 118 ? 56.04900 16.35600  5.58300   1.000 25.16847  ? 112 ALA L CB   1 
ATOM   4984 H H    . ALA B 2 118 ? 56.07300 16.36800  8.05400   1.000 26.86707  ? 112 ALA L H    1 
ATOM   4985 H HA   . ALA B 2 118 ? 54.47500 15.22800  6.24000   1.000 32.97926  ? 112 ALA L HA   1 
ATOM   4986 H HB1  . ALA B 2 118 ? 56.00200 16.02700  4.67100   1.000 30.20573  ? 112 ALA L HB1  1 
ATOM   4987 H HB2  . ALA B 2 118 ? 55.57300 17.19800  5.65500   1.000 30.20573  ? 112 ALA L HB2  1 
ATOM   4988 H HB3  . ALA B 2 118 ? 56.97500 16.47600  5.84400   1.000 30.20573  ? 112 ALA L HB3  1 
ATOM   4989 N N    . PRO B 2 119 ? 55.61700 13.12200  5.50000   1.000 22.79775  ? 113 PRO L N    1 
ATOM   4990 C CA   . PRO B 2 119 ? 56.24700 11.81100  5.33800   1.000 22.02824  ? 113 PRO L CA   1 
ATOM   4991 C C    . PRO B 2 119 ? 57.53700 11.88200  4.54300   1.000 23.05931  ? 113 PRO L C    1 
ATOM   4992 O O    . PRO B 2 119 ? 57.69400 12.68800  3.62300   1.000 23.19909  ? 113 PRO L O    1 
ATOM   4993 C CB   . PRO B 2 119 ? 55.19000 11.00100  4.57700   1.000 19.84665  ? 113 PRO L CB   1 
ATOM   4994 C CG   . PRO B 2 119 ? 54.44600 12.02200  3.79400   1.000 21.83834  ? 113 PRO L CG   1 
ATOM   4995 C CD   . PRO B 2 119 ? 54.42300 13.27100  4.64600   1.000 24.66869  ? 113 PRO L CD   1 
ATOM   4996 H HA   . PRO B 2 119 ? 56.41900 11.40900  6.20400   1.000 26.43746  ? 113 PRO L HA   1 
ATOM   4997 H HB2  . PRO B 2 119 ? 55.61900 10.35600  3.99400   1.000 23.81955  ? 113 PRO L HB2  1 
ATOM   4998 H HB3  . PRO B 2 119 ? 54.60500 10.54500  5.20200   1.000 23.81955  ? 113 PRO L HB3  1 
ATOM   4999 H HG2  . PRO B 2 119 ? 54.90600 12.18800  2.95600   1.000 26.20958  ? 113 PRO L HG2  1 
ATOM   5000 H HG3  . PRO B 2 119 ? 53.54500 11.70800  3.62100   1.000 26.20958  ? 113 PRO L HG3  1 
ATOM   5001 H HD2  . PRO B 2 119 ? 54.49000 14.06600  4.09500   1.000 29.60600  ? 113 PRO L HD2  1 
ATOM   5002 H HD3  . PRO B 2 119 ? 53.61700 13.30700  5.18400   1.000 29.60600  ? 113 PRO L HD3  1 
ATOM   5003 N N    . SER B 2 120 ? 58.47100 11.02000  4.92600   1.000 18.65580  ? 114 SER L N    1 
ATOM   5004 C CA   . SER B 2 120 ? 59.59700 10.68800  4.06600   1.000 18.85756  ? 114 SER L CA   1 
ATOM   5005 C C    . SER B 2 120 ? 59.13100 9.62100   3.08200   1.000 19.10864  ? 114 SER L C    1 
ATOM   5006 O O    . SER B 2 120 ? 58.63500 8.56800   3.49700   1.000 19.94979  ? 114 SER L O    1 
ATOM   5007 C CB   . SER B 2 120 ? 60.77800 10.19100  4.89000   1.000 21.63788  ? 114 SER L CB   1 
ATOM   5008 O OG   . SER B 2 120 ? 61.13600 11.13400  5.88400   1.000 28.63024  ? 114 SER L OG   1 
ATOM   5009 H H    . SER B 2 120 ? 58.47400 10.61100  5.68200   1.000 22.39053  ? 114 SER L H    1 
ATOM   5010 H HA   . SER B 2 120 ? 59.89600 11.47200  3.58000   1.000 22.63265  ? 114 SER L HA   1 
ATOM   5011 H HB2  . SER B 2 120 ? 60.53300 9.35700   5.32100   1.000 25.96902  ? 114 SER L HB2  1 
ATOM   5012 H HB3  . SER B 2 120 ? 61.53600 10.05000  4.30200   1.000 25.96902  ? 114 SER L HB3  1 
ATOM   5013 H HG   . SER B 2 120 ? 60.60800 11.07900  6.53500   1.000 34.35985  ? 114 SER L HG   1 
ATOM   5014 N N    . VAL B 2 121 ? 59.27000 9.89200   1.78700   1.000 17.59657  ? 115 VAL L N    1 
ATOM   5015 C CA   . VAL B 2 121 ? 58.70200 9.05200   0.73900   1.000 15.56496  ? 115 VAL L CA   1 
ATOM   5016 C C    . VAL B 2 121 ? 59.82500 8.28200   0.06000   1.000 19.78930  ? 115 VAL L C    1 
ATOM   5017 O O    . VAL B 2 121 ? 60.85000 8.86300   -0.31800  1.000 19.51833  ? 115 VAL L O    1 
ATOM   5018 C CB   . VAL B 2 121 ? 57.91300 9.88500   -0.28800  1.000 20.11946  ? 115 VAL L CB   1 
ATOM   5019 C CG1  . VAL B 2 121 ? 57.30100 8.98500   -1.36200  1.000 17.11701  ? 115 VAL L CG1  1 
ATOM   5020 C CG2  . VAL B 2 121 ? 56.83300 10.70300  0.40800   1.000 19.75825  ? 115 VAL L CG2  1 
ATOM   5021 H H    . VAL B 2 121 ? 59.69800 10.57400  1.48600   1.000 21.11945  ? 115 VAL L H    1 
ATOM   5022 H HA   . VAL B 2 121 ? 58.10000 8.41000   1.14700   1.000 18.68152  ? 115 VAL L HA   1 
ATOM   5023 H HB   . VAL B 2 121 ? 58.52400 10.49800  -0.72600  1.000 24.14692  ? 115 VAL L HB   1 
ATOM   5024 H HG11 . VAL B 2 121 ? 56.76800 9.52800   -1.96300  1.000 20.54399  ? 115 VAL L HG11 1 
ATOM   5025 H HG12 . VAL B 2 121 ? 58.01500 8.55000   -1.85400  1.000 20.54399  ? 115 VAL L HG12 1 
ATOM   5026 H HG13 . VAL B 2 121 ? 56.74100 8.31800   -0.93400  1.000 20.54399  ? 115 VAL L HG13 1 
ATOM   5027 H HG21 . VAL B 2 121 ? 56.32600 11.19100  -0.26100  1.000 23.71348  ? 115 VAL L HG21 1 
ATOM   5028 H HG22 . VAL B 2 121 ? 56.24600 10.10300  0.89400   1.000 23.71348  ? 115 VAL L HG22 1 
ATOM   5029 H HG23 . VAL B 2 121 ? 57.25400 11.32400  1.02200   1.000 23.71348  ? 115 VAL L HG23 1 
ATOM   5030 N N    . PHE B 2 122 ? 59.61900 6.97600   -0.10200  1.000 16.12576  ? 116 PHE L N    1 
ATOM   5031 C CA   . PHE B 2 122 ? 60.53200 6.09700   -0.81400  1.000 16.05502  ? 116 PHE L CA   1 
ATOM   5032 C C    . PHE B 2 122 ? 59.71900 5.26300   -1.79100  1.000 16.09833  ? 116 PHE L C    1 
ATOM   5033 O O    . PHE B 2 122 ? 58.60500 4.83900   -1.46900  1.000 15.01724  ? 116 PHE L O    1 
ATOM   5034 C CB   . PHE B 2 122 ? 61.28700 5.15600   0.13000   1.000 17.12733  ? 116 PHE L CB   1 
ATOM   5035 C CG   . PHE B 2 122 ? 62.02600 5.85400   1.23200   1.000 16.65650  ? 116 PHE L CG   1 
ATOM   5036 C CD1  . PHE B 2 122 ? 61.36300 6.27200   2.37000   1.000 18.45886  ? 116 PHE L CD1  1 
ATOM   5037 C CD2  . PHE B 2 122 ? 63.38800 6.07100   1.14100   1.000 20.93938  ? 116 PHE L CD2  1 
ATOM   5038 C CE1  . PHE B 2 122 ? 62.04200 6.90300   3.38800   1.000 18.75813  ? 116 PHE L CE1  1 
ATOM   5039 C CE2  . PHE B 2 122 ? 64.07200 6.70500   2.16000   1.000 21.15752  ? 116 PHE L CE2  1 
ATOM   5040 C CZ   . PHE B 2 122 ? 63.39900 7.11700   3.28200   1.000 19.76725  ? 116 PHE L CZ   1 
ATOM   5041 H H    . PHE B 2 122 ? 58.92900 6.56400   0.20400   1.000 19.35449  ? 116 PHE L H    1 
ATOM   5042 H HA   . PHE B 2 122 ? 61.18800 6.63000   -1.29000  1.000 19.26959  ? 116 PHE L HA   1 
ATOM   5043 H HB2  . PHE B 2 122 ? 60.64900 4.55200   0.54100   1.000 20.55637  ? 116 PHE L HB2  1 
ATOM   5044 H HB3  . PHE B 2 122 ? 61.93600 4.65300   -0.38600  1.000 20.55637  ? 116 PHE L HB3  1 
ATOM   5045 H HD1  . PHE B 2 122 ? 60.44800 6.12700   2.44900   1.000 22.15421  ? 116 PHE L HD1  1 
ATOM   5046 H HD2  . PHE B 2 122 ? 63.84900 5.78700   0.38500   1.000 25.13082  ? 116 PHE L HD2  1 
ATOM   5047 H HE1  . PHE B 2 122 ? 61.58500 7.18400   4.14800   1.000 22.51333  ? 116 PHE L HE1  1 
ATOM   5048 H HE2  . PHE B 2 122 ? 64.98700 6.85300   2.08500   1.000 25.39260  ? 116 PHE L HE2  1 
ATOM   5049 H HZ   . PHE B 2 122 ? 63.85900 7.54000   3.97100   1.000 23.72427  ? 116 PHE L HZ   1 
ATOM   5050 N N    . ILE B 2 123 ? 60.27800 5.02200   -2.97500  1.000 14.40580  ? 117 ILE L N    1 
ATOM   5051 C CA   . ILE B 2 123 ? 59.66600 4.16200   -3.98000  1.000 15.93803  ? 117 ILE L CA   1 
ATOM   5052 C C    . ILE B 2 123 ? 60.62000 3.01300   -4.28600  1.000 16.96963  ? 117 ILE L C    1 
ATOM   5053 O O    . ILE B 2 123 ? 61.83600 3.21500   -4.39500  1.000 15.17776  ? 117 ILE L O    1 
ATOM   5054 C CB   . ILE B 2 123 ? 59.31500 4.95200   -5.25800  1.000 15.48696  ? 117 ILE L CB   1 
ATOM   5055 C CG1  . ILE B 2 123 ? 58.57900 4.06100   -6.25900  1.000 16.05871  ? 117 ILE L CG1  1 
ATOM   5056 C CG2  . ILE B 2 123 ? 60.56900 5.52900   -5.87700  1.000 17.03737  ? 117 ILE L CG2  1 
ATOM   5057 C CD1  . ILE B 2 123 ? 57.91700 4.83300   -7.38900  1.000 14.96806  ? 117 ILE L CD1  1 
ATOM   5058 H H    . ILE B 2 123 ? 61.03100 5.35500   -3.22300  1.000 17.29053  ? 117 ILE L H    1 
ATOM   5059 H HA   . ILE B 2 123 ? 58.84700 3.78200   -3.62600  1.000 19.12920  ? 117 ILE L HA   1 
ATOM   5060 H HB   . ILE B 2 123 ? 58.72500 5.68200   -5.01400  1.000 18.58792  ? 117 ILE L HB   1 
ATOM   5061 H HG12 . ILE B 2 123 ? 59.21400 3.44300   -6.65400  1.000 19.27402  ? 117 ILE L HG12 1 
ATOM   5062 H HG13 . ILE B 2 123 ? 57.88600 3.57000   -5.79000  1.000 19.27402  ? 117 ILE L HG13 1 
ATOM   5063 H HG21 . ILE B 2 123 ? 60.32100 6.09500   -6.62400  1.000 20.44841  ? 117 ILE L HG21 1 
ATOM   5064 H HG22 . ILE B 2 123 ? 61.03900 6.05100   -5.20800  1.000 20.44841  ? 117 ILE L HG22 1 
ATOM   5065 H HG23 . ILE B 2 123 ? 61.13200 4.80200   -6.18500  1.000 20.44841  ? 117 ILE L HG23 1 
ATOM   5066 H HD11 . ILE B 2 123 ? 57.44900 4.20900   -7.96600  1.000 17.96525  ? 117 ILE L HD11 1 
ATOM   5067 H HD12 . ILE B 2 123 ? 57.28900 5.46900   -7.01100  1.000 17.96525  ? 117 ILE L HD12 1 
ATOM   5068 H HD13 . ILE B 2 123 ? 58.60000 5.30200   -7.89300  1.000 17.96525  ? 117 ILE L HD13 1 
ATOM   5069 N N    . PHE B 2 124 ? 60.06300 1.80700   -4.41700  1.000 15.95741  ? 118 PHE L N    1 
ATOM   5070 C CA   . PHE B 2 124 ? 60.82700 0.59000   -4.67300  1.000 15.54652  ? 118 PHE L CA   1 
ATOM   5071 C C    . PHE B 2 124 ? 60.35300 -0.06000  -5.96500  1.000 15.56856  ? 118 PHE L C    1 
ATOM   5072 O O    . PHE B 2 124 ? 59.16200 -0.39900  -6.07300  1.000 12.23614  ? 118 PHE L O    1 
ATOM   5073 C CB   . PHE B 2 124 ? 60.66900 -0.41300  -3.52400  1.000 16.38835  ? 118 PHE L CB   1 
ATOM   5074 C CG   . PHE B 2 124 ? 61.18500 0.07100   -2.20700  1.000 17.13806  ? 118 PHE L CG   1 
ATOM   5075 C CD1  . PHE B 2 124 ? 62.53100 -0.02600  -1.90200  1.000 18.03729  ? 118 PHE L CD1  1 
ATOM   5076 C CD2  . PHE B 2 124 ? 60.32100 0.59100   -1.26100  1.000 17.61906  ? 118 PHE L CD2  1 
ATOM   5077 C CE1  . PHE B 2 124 ? 63.00900 0.40500   -0.68600  1.000 18.97777  ? 118 PHE L CE1  1 
ATOM   5078 C CE2  . PHE B 2 124 ? 60.79500 1.02800   -0.04000  1.000 17.83776  ? 118 PHE L CE2  1 
ATOM   5079 C CZ   . PHE B 2 124 ? 62.14000 0.93400   0.24700   1.000 18.40803  ? 118 PHE L CZ   1 
ATOM   5080 H H    . PHE B 2 124 ? 59.21700 1.66600   -4.36000  1.000 19.15247  ? 118 PHE L H    1 
ATOM   5081 H HA   . PHE B 2 124 ? 61.76200 0.83400   -4.76200  1.000 18.65939  ? 118 PHE L HA   1 
ATOM   5082 H HB2  . PHE B 2 124 ? 59.72600 -0.61300  -3.41400  1.000 19.66959  ? 118 PHE L HB2  1 
ATOM   5083 H HB3  . PHE B 2 124 ? 61.15500 -1.22200  -3.75000  1.000 19.66959  ? 118 PHE L HB3  1 
ATOM   5084 H HD1  . PHE B 2 124 ? 63.11900 -0.38600  -2.52600  1.000 21.64832  ? 118 PHE L HD1  1 
ATOM   5085 H HD2  . PHE B 2 124 ? 59.41100 0.64600   -1.44900  1.000 21.14644  ? 118 PHE L HD2  1 
ATOM   5086 H HE1  . PHE B 2 124 ? 63.91600 0.34000   -0.49300  1.000 22.77689  ? 118 PHE L HE1  1 
ATOM   5087 H HE2  . PHE B 2 124 ? 60.20800 1.38600   0.58700   1.000 21.40888  ? 118 PHE L HE2  1 
ATOM   5088 H HZ   . PHE B 2 124 ? 62.46200 1.22600   1.06900   1.000 22.09320  ? 118 PHE L HZ   1 
ATOM   5089 N N    . PRO B 2 125 ? 61.21800 -0.27800  -6.95300  1.000 15.77711  ? 119 PRO L N    1 
ATOM   5090 C CA   . PRO B 2 125 ? 60.81800 -1.06000  -8.12300  1.000 15.77676  ? 119 PRO L CA   1 
ATOM   5091 C C    . PRO B 2 125 ? 60.64500 -2.52100  -7.75700  1.000 17.61751  ? 119 PRO L C    1 
ATOM   5092 O O    . PRO B 2 125 ? 61.15700 -2.97800  -6.72400  1.000 16.46721  ? 119 PRO L O    1 
ATOM   5093 C CB   . PRO B 2 125 ? 61.99000 -0.87400  -9.10200  1.000 19.05831  ? 119 PRO L CB   1 
ATOM   5094 C CG   . PRO B 2 125 ? 62.83700 0.21600   -8.53100  1.000 20.94998  ? 119 PRO L CG   1 
ATOM   5095 C CD   . PRO B 2 125 ? 62.61000 0.19200   -7.06000  1.000 18.53858  ? 119 PRO L CD   1 
ATOM   5096 H HA   . PRO B 2 125 ? 60.00200 -0.71000  -8.51300  1.000 18.93569  ? 119 PRO L HA   1 
ATOM   5097 H HB2  . PRO B 2 125 ? 62.49400 -1.70000  -9.16900  1.000 22.87354  ? 119 PRO L HB2  1 
ATOM   5098 H HB3  . PRO B 2 125 ? 61.64900 -0.62200  -9.97500  1.000 22.87354  ? 119 PRO L HB3  1 
ATOM   5099 H HG2  . PRO B 2 125 ? 63.76900 0.04500   -8.73600  1.000 25.14355  ? 119 PRO L HG2  1 
ATOM   5100 H HG3  . PRO B 2 125 ? 62.56500 1.06800   -8.90500  1.000 25.14355  ? 119 PRO L HG3  1 
ATOM   5101 H HD2  . PRO B 2 125 ? 63.21900 -0.42400  -6.62500  1.000 22.24987  ? 119 PRO L HD2  1 
ATOM   5102 H HD3  . PRO B 2 125 ? 62.70700 1.07900   -6.68000  1.000 22.24987  ? 119 PRO L HD3  1 
ATOM   5103 N N    . PRO B 2 126 ? 59.95000 -3.29800  -8.58200  1.000 18.45887  ? 120 PRO L N    1 
ATOM   5104 C CA   . PRO B 2 126 ? 59.90600 -4.74600  -8.34900  1.000 18.98889  ? 120 PRO L CA   1 
ATOM   5105 C C    . PRO B 2 126 ? 61.29400 -5.36200  -8.44800  1.000 18.30728  ? 120 PRO L C    1 
ATOM   5106 O O    . PRO B 2 126 ? 62.14500 -4.92000  -9.22300  1.000 19.26613  ? 120 PRO L O    1 
ATOM   5107 C CB   . PRO B 2 126 ? 58.98100 -5.26100  -9.46100  1.000 19.33822  ? 120 PRO L CB   1 
ATOM   5108 C CG   . PRO B 2 126 ? 59.02000 -4.20100  -10.51100 1.000 21.80022  ? 120 PRO L CG   1 
ATOM   5109 C CD   . PRO B 2 126 ? 59.18000 -2.90400  -9.77500  1.000 16.21651  ? 120 PRO L CD   1 
ATOM   5110 H HA   . PRO B 2 126 ? 59.51800 -4.94700  -7.48300  1.000 22.79024  ? 120 PRO L HA   1 
ATOM   5111 H HB2  . PRO B 2 126 ? 59.31500 -6.10400  -9.80500  1.000 23.20943  ? 120 PRO L HB2  1 
ATOM   5112 H HB3  . PRO B 2 126 ? 58.08200 -5.37600  -9.11600  1.000 23.20943  ? 120 PRO L HB3  1 
ATOM   5113 H HG2  . PRO B 2 126 ? 59.77100 -4.35500  -11.10400 1.000 26.16384  ? 120 PRO L HG2  1 
ATOM   5114 H HG3  . PRO B 2 126 ? 58.19100 -4.21000  -11.01500 1.000 26.16384  ? 120 PRO L HG3  1 
ATOM   5115 H HD2  . PRO B 2 126 ? 59.67200 -2.26100  -10.30800 1.000 19.46338  ? 120 PRO L HD2  1 
ATOM   5116 H HD3  . PRO B 2 126 ? 58.31700 -2.53700  -9.52500  1.000 19.46338  ? 120 PRO L HD3  1 
ATOM   5117 N N    . SER B 2 127 ? 61.51300 -6.40400  -7.65200  1.000 17.96564  ? 121 SER L N    1 
ATOM   5118 C CA   . SER B 2 127 ? 62.77100 -7.13200  -7.70200  1.000 20.61632  ? 121 SER L CA   1 
ATOM   5119 C C    . SER B 2 127 ? 62.84300 -7.99300  -8.95900  1.000 22.14742  ? 121 SER L C    1 
ATOM   5120 O O    . SER B 2 127 ? 61.82500 -8.45300  -9.48200  1.000 21.51612  ? 121 SER L O    1 
ATOM   5121 C CB   . SER B 2 127 ? 62.92100 -8.02100  -6.47200  1.000 19.78745  ? 121 SER L CB   1 
ATOM   5122 O OG   . SER B 2 127 ? 61.99600 -9.09500  -6.52400  1.000 17.79683  ? 121 SER L OG   1 
ATOM   5123 H H    . SER B 2 127 ? 60.95000 -6.70700  -7.07600  1.000 21.56234  ? 121 SER L H    1 
ATOM   5124 H HA   . SER B 2 127 ? 63.50600 -6.49900  -7.71700  1.000 24.74315  ? 121 SER L HA   1 
ATOM   5125 H HB2  . SER B 2 127 ? 63.82200 -8.37900  -6.44600  1.000 23.74852  ? 121 SER L HB2  1 
ATOM   5126 H HB3  . SER B 2 127 ? 62.75100 -7.49400  -5.67600  1.000 23.74852  ? 121 SER L HB3  1 
ATOM   5127 H HG   . SER B 2 127 ? 62.09000 -9.58700  -5.85000  1.000 21.35976  ? 121 SER L HG   1 
ATOM   5128 N N    . ASP B 2 128 ? 64.06700 -8.21600  -9.44300  1.000 24.36690  ? 122 ASP L N    1 
ATOM   5129 C CA   . ASP B 2 128 ? 64.24500 -9.13700  -10.56000 1.000 27.17841  ? 122 ASP L CA   1 
ATOM   5130 C C    . ASP B 2 128 ? 63.75000 -10.53100 -10.20200 1.000 25.08707  ? 122 ASP L C    1 
ATOM   5131 O O    . ASP B 2 128 ? 63.19500 -11.23300 -11.05400 1.000 26.98820  ? 122 ASP L O    1 
ATOM   5132 C CB   . ASP B 2 128 ? 65.71200 -9.17400  -10.98300 1.000 30.41833  ? 122 ASP L CB   1 
ATOM   5133 C CG   . ASP B 2 128 ? 66.19100 -7.84300  -11.53300 1.000 39.61978  ? 122 ASP L CG   1 
ATOM   5134 O OD1  . ASP B 2 128 ? 65.37500 -7.12500  -12.15200 1.000 36.38863  ? 122 ASP L OD1  1 
ATOM   5135 O OD2  . ASP B 2 128 ? 67.38200 -7.51300  -11.34300 1.000 45.54929  ? 122 ASP L OD2  1 
ATOM   5136 H H    . ASP B 2 128 ? 64.79100 -7.85700  -9.14800  1.000 29.24385  ? 122 ASP L H    1 
ATOM   5137 H HA   . ASP B 2 128 ? 63.73200 -8.82100  -11.32100 1.000 32.61766  ? 122 ASP L HA   1 
ATOM   5138 H HB2  . ASP B 2 128 ? 66.25900 -9.39600  -10.21300 1.000 36.50557  ? 122 ASP L HB2  1 
ATOM   5139 H HB3  . ASP B 2 128 ? 65.82600 -9.84500  -11.67500 1.000 36.50557  ? 122 ASP L HB3  1 
ATOM   5140 N N    . GLU B 2 129 ? 63.90900 -10.93600 -8.94100  1.000 26.85907  ? 123 GLU L N    1 
ATOM   5141 C CA   . GLU B 2 129 ? 63.40400 -12.23800 -8.51900  1.000 25.25765  ? 123 GLU L CA   1 
ATOM   5142 C C    . GLU B 2 129 ? 61.90400 -12.34800 -8.77800  1.000 24.63848  ? 123 GLU L C    1 
ATOM   5143 O O    . GLU B 2 129 ? 61.43800 -13.32400 -9.37700  1.000 21.77487  ? 123 GLU L O    1 
ATOM   5144 C CB   . GLU B 2 129 ? 63.72600 -12.46300 -7.04200  1.000 26.90829  ? 123 GLU L CB   1 
ATOM   5145 C CG   . GLU B 2 129 ? 63.46900 -13.88200 -6.56400  1.000 32.58868  ? 123 GLU L CG   1 
ATOM   5146 C CD   . GLU B 2 129 ? 63.70100 -14.05300 -5.07300  1.000 35.23916  ? 123 GLU L CD   1 
ATOM   5147 O OE1  . GLU B 2 129 ? 64.33000 -13.16500 -4.45800  1.000 32.18892  ? 123 GLU L OE1  1 
ATOM   5148 O OE2  . GLU B 2 129 ? 63.25200 -15.07700 -4.51600  1.000 32.93880  ? 123 GLU L OE2  1 
ATOM   5149 H H    . GLU B 2 129 ? 64.29900 -10.48400 -8.32300  1.000 32.23445  ? 123 GLU L H    1 
ATOM   5150 H HA   . GLU B 2 129 ? 63.84600 -12.93400 -9.02900  1.000 30.31275  ? 123 GLU L HA   1 
ATOM   5151 H HB2  . GLU B 2 129 ? 64.66500 -12.26700 -6.89500  1.000 32.29352  ? 123 GLU L HB2  1 
ATOM   5152 H HB3  . GLU B 2 129 ? 63.17500 -11.86800 -6.50900  1.000 32.29352  ? 123 GLU L HB3  1 
ATOM   5153 H HG2  . GLU B 2 129 ? 62.54700 -14.11700 -6.75200  1.000 39.10999  ? 123 GLU L HG2  1 
ATOM   5154 H HG3  . GLU B 2 129 ? 64.06800 -14.48600 -7.03100  1.000 39.10999  ? 123 GLU L HG3  1 
ATOM   5155 N N    . GLN B 2 130 ? 61.13200 -11.34100 -8.35500  1.000 21.81731  ? 124 GLN L N    1 
ATOM   5156 C CA   . GLN B 2 130 ? 59.68400 -11.40200 -8.53200  1.000 20.59624  ? 124 GLN L CA   1 
ATOM   5157 C C    . GLN B 2 130 ? 59.29900 -11.38400 -10.00800 1.000 22.95750  ? 124 GLN L C    1 
ATOM   5158 O O    . GLN B 2 130 ? 58.34600 -12.05800 -10.41500 1.000 23.96705  ? 124 GLN L O    1 
ATOM   5159 C CB   . GLN B 2 130 ? 58.99900 -10.24000 -7.80500  1.000 19.30709  ? 124 GLN L CB   1 
ATOM   5160 C CG   . GLN B 2 130 ? 57.47600 -10.32300 -7.86400  1.000 18.78691  ? 124 GLN L CG   1 
ATOM   5161 C CD   . GLN B 2 130 ? 56.75800 -9.08000  -7.36300  1.000 20.49901  ? 124 GLN L CD   1 
ATOM   5162 O OE1  . GLN B 2 130 ? 57.32800 -7.98500  -7.28800  1.000 18.42780  ? 124 GLN L OE1  1 
ATOM   5163 N NE2  . GLN B 2 130 ? 55.48500 -9.24900  -7.02000  1.000 18.64625  ? 124 GLN L NE2  1 
ATOM   5164 H H    . GLN B 2 130 ? 61.41900 -10.62700 -7.97100  1.000 26.18434  ? 124 GLN L H    1 
ATOM   5165 H HA   . GLN B 2 130 ? 59.37200 -12.23200 -8.14000  1.000 24.71906  ? 124 GLN L HA   1 
ATOM   5166 H HB2  . GLN B 2 130 ? 59.26500 -10.25100 -6.87200  1.000 23.17208  ? 124 GLN L HB2  1 
ATOM   5167 H HB3  . GLN B 2 130 ? 59.27100 -9.40500  -8.21700  1.000 23.17208  ? 124 GLN L HB3  1 
ATOM   5168 H HG2  . GLN B 2 130 ? 57.20900 -10.46300 -8.78600  1.000 22.54786  ? 124 GLN L HG2  1 
ATOM   5169 H HG3  . GLN B 2 130 ? 57.18500 -11.07000 -7.31800  1.000 22.54786  ? 124 GLN L HG3  1 
ATOM   5170 H HE21 . GLN B 2 130 ? 55.12000 -10.02500 -7.09000  1.000 22.37907  ? 124 GLN L HE21 1 
ATOM   5171 H HE22 . GLN B 2 130 ? 55.02600 -8.58300  -6.72900  1.000 22.37907  ? 124 GLN L HE22 1 
ATOM   5172 N N    . LEU B 2 131 ? 60.00600 -10.60000 -10.82300 1.000 22.41599  ? 125 LEU L N    1 
ATOM   5173 C CA   . LEU B 2 131 ? 59.62400 -10.49600 -12.22700 1.000 24.57711  ? 125 LEU L CA   1 
ATOM   5174 C C    . LEU B 2 131 ? 59.66000 -11.85600 -12.91400 1.000 29.25922  ? 125 LEU L C    1 
ATOM   5175 O O    . LEU B 2 131 ? 58.82200 -12.13800 -13.77800 1.000 29.23899  ? 125 LEU L O    1 
ATOM   5176 C CB   . LEU B 2 131 ? 60.53000 -9.50300  -12.94700 1.000 25.44749  ? 125 LEU L CB   1 
ATOM   5177 C CG   . LEU B 2 131 ? 60.31100 -8.03000  -12.59700 1.000 24.83782  ? 125 LEU L CG   1 
ATOM   5178 C CD1  . LEU B 2 131 ? 61.24500 -7.16000  -13.42700 1.000 27.12869  ? 125 LEU L CD1  1 
ATOM   5179 C CD2  . LEU B 2 131 ? 58.86300 -7.62400  -12.81500 1.000 23.39757  ? 125 LEU L CD2  1 
ATOM   5180 H H    . LEU B 2 131 ? 60.69100 -10.13200 -10.59400 1.000 26.90275  ? 125 LEU L H    1 
ATOM   5181 H HA   . LEU B 2 131 ? 58.71600 -10.15900 -12.28300 1.000 29.49610  ? 125 LEU L HA   1 
ATOM   5182 H HB2  . LEU B 2 131 ? 61.45000 -9.71800  -12.72700 1.000 30.54056  ? 125 LEU L HB2  1 
ATOM   5183 H HB3  . LEU B 2 131 ? 60.38500 -9.59700  -13.90100 1.000 30.54056  ? 125 LEU L HB3  1 
ATOM   5184 H HG   . LEU B 2 131 ? 60.51100 -7.89200  -11.65800 1.000 29.80896  ? 125 LEU L HG   1 
ATOM   5185 H HD11 . LEU B 2 131 ? 61.07700 -6.22800  -13.21800 1.000 32.55800  ? 125 LEU L HD11 1 
ATOM   5186 H HD12 . LEU B 2 131 ? 62.16300 -7.38700  -13.21000 1.000 32.55800  ? 125 LEU L HD12 1 
ATOM   5187 H HD13 . LEU B 2 131 ? 61.07600 -7.32500  -14.36800 1.000 32.55800  ? 125 LEU L HD13 1 
ATOM   5188 H HD21 . LEU B 2 131 ? 58.79100 -6.65900  -12.74500 1.000 28.08065  ? 125 LEU L HD21 1 
ATOM   5189 H HD22 . LEU B 2 131 ? 58.58300 -7.91300  -13.69700 1.000 28.08065  ? 125 LEU L HD22 1 
ATOM   5190 H HD23 . LEU B 2 131 ? 58.31200 -8.04600  -12.13800 1.000 28.08065  ? 125 LEU L HD23 1 
ATOM   5191 N N    . LYS B 2 132 ? 60.59500 -12.72500 -12.52600 1.000 29.25934  ? 126 LYS L N    1 
ATOM   5192 C CA   . LYS B 2 132 ? 60.62300 -14.06900 -13.09200 1.000 28.33778  ? 126 LYS L CA   1 
ATOM   5193 C C    . LYS B 2 132 ? 59.31700 -14.82000 -12.86100 1.000 29.30853  ? 126 LYS L C    1 
ATOM   5194 O O    . LYS B 2 132 ? 59.05300 -15.80500 -13.56000 1.000 34.53919  ? 126 LYS L O    1 
ATOM   5195 C CB   . LYS B 2 132 ? 61.79800 -14.85900 -12.50800 1.000 28.25759  ? 126 LYS L CB   1 
ATOM   5196 C CG   . LYS B 2 132 ? 63.15400 -14.38000 -13.01700 1.000 34.40846  ? 126 LYS L CG   1 
ATOM   5197 C CD   . LYS B 2 132 ? 64.30500 -15.26800 -12.56200 1.000 38.03929  ? 126 LYS L CD   1 
ATOM   5198 C CE   . LYS B 2 132 ? 64.56700 -15.13300 -11.07300 1.000 36.78884  ? 126 LYS L CE   1 
ATOM   5199 N NZ   . LYS B 2 132 ? 65.90200 -15.67900 -10.69400 1.000 39.23940  ? 126 LYS L NZ   1 
ATOM   5200 H H    . LYS B 2 132 ? 61.21100 -12.56300 -11.94900 1.000 35.11478  ? 126 LYS L H    1 
ATOM   5201 H HA   . LYS B 2 132 ? 60.75700 -14.00200 -14.05000 1.000 34.00891  ? 126 LYS L HA   1 
ATOM   5202 H HB2  . LYS B 2 132 ? 61.79100 -14.76400 -11.54300 1.000 33.91267  ? 126 LYS L HB2  1 
ATOM   5203 H HB3  . LYS B 2 132 ? 61.70100 -15.79300 -12.75100 1.000 33.91267  ? 126 LYS L HB3  1 
ATOM   5204 H HG2  . LYS B 2 132 ? 63.14500 -14.37700 -13.98700 1.000 41.29373  ? 126 LYS L HG2  1 
ATOM   5205 H HG3  . LYS B 2 132 ? 63.31900 -13.48400 -12.68400 1.000 41.29373  ? 126 LYS L HG3  1 
ATOM   5206 H HD2  . LYS B 2 132 ? 64.08700 -16.19500 -12.74900 1.000 45.65071  ? 126 LYS L HD2  1 
ATOM   5207 H HD3  . LYS B 2 132 ? 65.11200 -15.01500 -13.03700 1.000 45.65071  ? 126 LYS L HD3  1 
ATOM   5208 H HE2  . LYS B 2 132 ? 64.54200 -14.19400 -10.82800 1.000 44.15018  ? 126 LYS L HE2  1 
ATOM   5209 H HE3  . LYS B 2 132 ? 63.88800 -15.62200 -10.58300 1.000 44.15018  ? 126 LYS L HE3  1 
ATOM   5210 H HZ1  . LYS B 2 132 ? 66.02900 -15.59000 -9.81800  1.000 47.09085  ? 126 LYS L HZ1  1 
ATOM   5211 H HZ2  . LYS B 2 132 ? 65.94800 -16.54200 -10.90600 1.000 47.09085  ? 126 LYS L HZ2  1 
ATOM   5212 H HZ3  . LYS B 2 132 ? 66.54400 -15.24100 -11.12600 1.000 47.09085  ? 126 LYS L HZ3  1 
ATOM   5213 N N    . SER B 2 133 ? 58.48800 -14.37200 -11.91700 1.000 28.54861  ? 127 SER L N    1 
ATOM   5214 C CA   A SER B 2 133 ? 57.22700 -15.02800 -11.59400 0.610 28.44801  ? 127 SER L CA   1 
ATOM   5215 C CA   B SER B 2 133 ? 57.23300 -15.04500 -11.61000 0.390 28.40868  ? 127 SER L CA   1 
ATOM   5216 C C    . SER B 2 133 ? 56.05900 -14.52000 -12.42800 1.000 30.04908  ? 127 SER L C    1 
ATOM   5217 O O    . SER B 2 133 ? 54.94900 -15.04900 -12.29800 1.000 32.99936  ? 127 SER L O    1 
ATOM   5218 C CB   A SER B 2 133 ? 56.89200 -14.84100 -10.10900 0.610 28.71944  ? 127 SER L CB   1 
ATOM   5219 C CB   B SER B 2 133 ? 56.92000 -14.90900 -10.11600 0.390 28.66946  ? 127 SER L CB   1 
ATOM   5220 O OG   A SER B 2 133 ? 56.32700 -13.56100 -9.86100  0.610 27.88884  ? 127 SER L OG   1 
ATOM   5221 O OG   B SER B 2 133 ? 57.98000 -15.42400 -9.32600  0.390 26.27879  ? 127 SER L OG   1 
ATOM   5222 H H    A SER B 2 133 ? 58.64000 -13.67300 -11.44000 0.610 34.26191  ? 127 SER L H    1 
ATOM   5223 H H    B SER B 2 133 ? 58.63500 -13.67300 -11.43800 0.390 34.26191  ? 127 SER L H    1 
ATOM   5224 H HA   A SER B 2 133 ? 57.33300 -15.97700 -11.76500 0.610 34.14118  ? 127 SER L HA   1 
ATOM   5225 H HA   B SER B 2 133 ? 57.33100 -15.98800 -11.81200 0.390 34.09399  ? 127 SER L HA   1 
ATOM   5226 H HB2  A SER B 2 133 ? 56.25400 -15.52200 -9.84300  0.610 34.46690  ? 127 SER L HB2  1 
ATOM   5227 H HB2  B SER B 2 133 ? 56.79700 -13.97000 -9.90400  0.390 34.40692  ? 127 SER L HB2  1 
ATOM   5228 H HB3  A SER B 2 133 ? 57.70700 -14.93000 -9.59000  0.610 34.46690  ? 127 SER L HB3  1 
ATOM   5229 H HB3  B SER B 2 133 ? 56.11000 -15.40300 -9.91700  0.390 34.40692  ? 127 SER L HB3  1 
ATOM   5230 H HG   A SER B 2 133 ? 56.86200 -12.95900 -10.10000 0.610 33.47018  ? 127 SER L HG   1 
ATOM   5231 H HG   B SER B 2 133 ? 57.81100 -15.31200 -8.51100  0.390 31.53812  ? 127 SER L HG   1 
ATOM   5232 N N    . GLY B 2 134 ? 56.27000 -13.50300 -13.26100 1.000 27.46795  ? 128 GLY L N    1 
ATOM   5233 C CA   . GLY B 2 134 ? 55.21200 -12.95300 -14.08000 1.000 27.34813  ? 128 GLY L CA   1 
ATOM   5234 C C    . GLY B 2 134 ? 54.39000 -11.85100 -13.44500 1.000 28.36887  ? 128 GLY L C    1 
ATOM   5235 O O    . GLY B 2 134 ? 53.47300 -11.33500 -14.09800 1.000 24.69690  ? 128 GLY L O    1 
ATOM   5236 H H    . GLY B 2 134 ? 57.03000 -13.11400 -13.36500 1.000 32.96511  ? 128 GLY L H    1 
ATOM   5237 H HA2  . GLY B 2 134 ? 55.60600 -12.59200 -14.89000 1.000 32.82133  ? 128 GLY L HA2  1 
ATOM   5238 H HA3  . GLY B 2 134 ? 54.60400 -13.67000 -14.31800 1.000 32.82133  ? 128 GLY L HA3  1 
ATOM   5239 N N    . THR B 2 135 ? 54.68200 -11.47200 -12.20000 1.000 26.08751  ? 129 THR L N    1 
ATOM   5240 C CA   . THR B 2 135 ? 53.99300 -10.38800 -11.51400 1.000 25.91780  ? 129 THR L CA   1 
ATOM   5241 C C    . THR B 2 135 ? 55.00800 -9.35800  -11.03200 1.000 22.02678  ? 129 THR L C    1 
ATOM   5242 O O    . THR B 2 135 ? 56.14600 -9.69600  -10.69800 1.000 18.07522  ? 129 THR L O    1 
ATOM   5243 C CB   . THR B 2 135 ? 53.17700 -10.91000 -10.32100 1.000 31.13940  ? 129 THR L CB   1 
ATOM   5244 O OG1  . THR B 2 135 ? 52.16700 -11.81000 -10.79300 1.000 36.62844  ? 129 THR L OG1  1 
ATOM   5245 C CG2  . THR B 2 135 ? 52.51800 -9.75900  -9.56200  1.000 27.70870  ? 129 THR L CG2  1 
ATOM   5246 H H    . THR B 2 135 ? 55.29300 -11.84200 -11.72100 1.000 31.30858  ? 129 THR L H    1 
ATOM   5247 H HA   . THR B 2 135 ? 53.38300 -9.95100  -12.12900 1.000 31.10493  ? 129 THR L HA   1 
ATOM   5248 H HB   . THR B 2 135 ? 53.76800 -11.37300 -9.70700  1.000 37.37085  ? 129 THR L HB   1 
ATOM   5249 H HG1  . THR B 2 135 ? 51.68900 -12.06700 -10.15100 1.000 43.95770  ? 129 THR L HG1  1 
ATOM   5250 H HG21 . THR B 2 135 ? 51.89600 -10.10900 -8.90500  1.000 33.25401  ? 129 THR L HG21 1 
ATOM   5251 H HG22 . THR B 2 135 ? 53.19300 -9.23300  -9.10700  1.000 33.25401  ? 129 THR L HG22 1 
ATOM   5252 H HG23 . THR B 2 135 ? 52.03600 -9.18700  -10.18000 1.000 33.25401  ? 129 THR L HG23 1 
ATOM   5253 N N    . ALA B 2 136 ? 54.58500 -8.09400  -11.00100 1.000 22.54789  ? 130 ALA L N    1 
ATOM   5254 C CA   . ALA B 2 136 ? 55.44400 -6.98600  -10.60000 1.000 20.94857  ? 130 ALA L CA   1 
ATOM   5255 C C    . ALA B 2 136 ? 54.73900 -6.16700  -9.53200  1.000 19.25777  ? 130 ALA L C    1 
ATOM   5256 O O    . ALA B 2 136 ? 53.63500 -5.66400  -9.76400  1.000 21.37961  ? 130 ALA L O    1 
ATOM   5257 C CB   . ALA B 2 136 ? 55.79300 -6.09700  -11.79800 1.000 21.70834  ? 130 ALA L CB   1 
ATOM   5258 H H    . ALA B 2 136 ? 53.78800 -7.85100  -11.21300 1.000 27.06104  ? 130 ALA L H    1 
ATOM   5259 H HA   . ALA B 2 136 ? 56.26300 -7.34200  -10.22200 1.000 25.14185  ? 130 ALA L HA   1 
ATOM   5260 H HB1  . ALA B 2 136 ? 56.36000 -5.36900  -11.49600 1.000 26.05358  ? 130 ALA L HB1  1 
ATOM   5261 H HB2  . ALA B 2 136 ? 56.26200 -6.62900  -12.46000 1.000 26.05358  ? 130 ALA L HB2  1 
ATOM   5262 H HB3  . ALA B 2 136 ? 54.97400 -5.74200  -12.17800 1.000 26.05358  ? 130 ALA L HB3  1 
ATOM   5263 N N    . SER B 2 137 ? 55.38000 -6.02000  -8.37500  1.000 14.90553  ? 131 SER L N    1 
ATOM   5264 C CA   . SER B 2 137 ? 54.86900 -5.19900  -7.28500  1.000 15.73536  ? 131 SER L CA   1 
ATOM   5265 C C    . SER B 2 137 ? 55.74300 -3.96000  -7.14400  1.000 16.95863  ? 131 SER L C    1 
ATOM   5266 O O    . SER B 2 137 ? 56.95300 -4.07300  -6.92400  1.000 16.61800  ? 131 SER L O    1 
ATOM   5267 C CB   . SER B 2 137 ? 54.84700 -5.97700  -5.96900  1.000 18.18858  ? 131 SER L CB   1 
ATOM   5268 O OG   . SER B 2 137 ? 54.00000 -7.11100  -6.04800  1.000 16.83785  ? 131 SER L OG   1 
ATOM   5269 H H    . SER B 2 137 ? 56.13200 -6.39700  -8.19500  1.000 17.89021  ? 131 SER L H    1 
ATOM   5270 H HA   . SER B 2 137 ? 53.96400 -4.92100  -7.49700  1.000 18.88600  ? 131 SER L HA   1 
ATOM   5271 H HB2  . SER B 2 137 ? 55.74800 -6.27300  -5.76500  1.000 21.82987  ? 131 SER L HB2  1 
ATOM   5272 H HB3  . SER B 2 137 ? 54.52200 -5.39300  -5.26500  1.000 21.82987  ? 131 SER L HB3  1 
ATOM   5273 H HG   . SER B 2 137 ? 53.23200 -6.91500  -5.77200  1.000 20.20899  ? 131 SER L HG   1 
ATOM   5274 N N    . VAL B 2 138 ? 55.12800 -2.78600  -7.26100  1.000 15.32754  ? 132 VAL L N    1 
ATOM   5275 C CA   . VAL B 2 138 ? 55.80000 -1.50800  -7.05000  1.000 14.33692  ? 132 VAL L CA   1 
ATOM   5276 C C    . VAL B 2 138 ? 55.31400 -0.95800  -5.71800  1.000 12.91486  ? 132 VAL L C    1 
ATOM   5277 O O    . VAL B 2 138 ? 54.10300 -0.86200  -5.49000  1.000 14.09787  ? 132 VAL L O    1 
ATOM   5278 C CB   . VAL B 2 138 ? 55.51100 -0.51400  -8.18700  1.000 16.69887  ? 132 VAL L CB   1 
ATOM   5279 C CG1  . VAL B 2 138 ? 56.54200 0.60700   -8.18700  1.000 14.81830  ? 132 VAL L CG1  1 
ATOM   5280 C CG2  . VAL B 2 138 ? 55.48900 -1.21400  -9.53300  1.000 15.78769  ? 132 VAL L CG2  1 
ATOM   5281 H H    . VAL B 2 138 ? 54.29800 -2.70200  -7.46700  1.000 18.39661  ? 132 VAL L H    1 
ATOM   5282 H HA   . VAL B 2 138 ? 56.75900 -1.64700  -7.01200  1.000 17.20788  ? 132 VAL L HA   1 
ATOM   5283 H HB   . VAL B 2 138 ? 54.63400 -0.12600  -8.04000  1.000 20.04222  ? 132 VAL L HB   1 
ATOM   5284 H HG11 . VAL B 2 138 ? 56.34500 1.21700   -8.91500  1.000 17.78553  ? 132 VAL L HG11 1 
ATOM   5285 H HG12 . VAL B 2 138 ? 56.49600 1.07700   -7.34000  1.000 17.78553  ? 132 VAL L HG12 1 
ATOM   5286 H HG13 . VAL B 2 138 ? 57.42500 0.22300   -8.30500  1.000 17.78553  ? 132 VAL L HG13 1 
ATOM   5287 H HG21 . VAL B 2 138 ? 55.41900 -0.54800  -10.23500 1.000 18.94880  ? 132 VAL L HG21 1 
ATOM   5288 H HG22 . VAL B 2 138 ? 56.31000 -1.72100  -9.63900  1.000 18.94880  ? 132 VAL L HG22 1 
ATOM   5289 H HG23 . VAL B 2 138 ? 54.72500 -1.81100  -9.56700  1.000 18.94880  ? 132 VAL L HG23 1 
ATOM   5290 N N    . VAL B 2 139 ? 56.24500 -0.58400  -4.84700  1.000 12.68488  ? 133 VAL L N    1 
ATOM   5291 C CA   . VAL B 2 139 ? 55.92200 -0.23800  -3.47000  1.000 11.76460  ? 133 VAL L CA   1 
ATOM   5292 C C    . VAL B 2 139 ? 56.31800 1.20500   -3.20200  1.000 15.42937  ? 133 VAL L C    1 
ATOM   5293 O O    . VAL B 2 139 ? 57.44400 1.61600   -3.50700  1.000 16.08898  ? 133 VAL L O    1 
ATOM   5294 C CB   . VAL B 2 139 ? 56.61600 -1.18000  -2.46900  1.000 13.63701  ? 133 VAL L CB   1 
ATOM   5295 C CG1  . VAL B 2 139 ? 56.30900 -0.75000  -1.03900  1.000 17.18925  ? 133 VAL L CG1  1 
ATOM   5296 C CG2  . VAL B 2 139 ? 56.18600 -2.62300  -2.70400  1.000 16.30823  ? 133 VAL L CG2  1 
ATOM   5297 H H    . VAL B 2 139 ? 57.08300 -0.52300  -5.03500  1.000 15.22543  ? 133 VAL L H    1 
ATOM   5298 H HA   . VAL B 2 139 ? 54.96100 -0.30700  -3.35500  1.000 14.12110  ? 133 VAL L HA   1 
ATOM   5299 H HB   . VAL B 2 139 ? 57.57500 -1.13000  -2.60200  1.000 16.36799  ? 133 VAL L HB   1 
ATOM   5300 H HG11 . VAL B 2 139 ? 56.63100 -1.43200  -0.42800  1.000 20.63067  ? 133 VAL L HG11 1 
ATOM   5301 H HG12 . VAL B 2 139 ? 56.75600 0.09200   -0.85900  1.000 20.63067  ? 133 VAL L HG12 1 
ATOM   5302 H HG13 . VAL B 2 139 ? 55.35000 -0.64400  -0.94000  1.000 20.63067  ? 133 VAL L HG13 1 
ATOM   5303 H HG21 . VAL B 2 139 ? 56.60600 -3.19000  -2.03800  1.000 19.57345  ? 133 VAL L HG21 1 
ATOM   5304 H HG22 . VAL B 2 139 ? 55.22100 -2.68200  -2.62700  1.000 19.57345  ? 133 VAL L HG22 1 
ATOM   5305 H HG23 . VAL B 2 139 ? 56.46400 -2.89500  -3.59300  1.000 19.57345  ? 133 VAL L HG23 1 
ATOM   5306 N N    . CYS B 2 140 ? 55.39300 1.95900   -2.61100  1.000 14.17742  ? 134 CYS L N    1 
ATOM   5307 C CA   . CYS B 2 140 ? 55.61300 3.33000   -2.17600  1.000 13.40444  ? 134 CYS L CA   1 
ATOM   5308 C C    . CYS B 2 140 ? 55.48000 3.37500   -0.66200  1.000 15.10812  ? 134 CYS L C    1 
ATOM   5309 O O    . CYS B 2 140 ? 54.46600 2.93100   -0.11200  1.000 16.26892  ? 134 CYS L O    1 
ATOM   5310 C CB   . CYS B 2 140 ? 54.60400 4.27100   -2.83000  1.000 14.57645  ? 134 CYS L CB   1 
ATOM   5311 S SG   . CYS B 2 140 ? 54.90500 6.04600   -2.60400  1.000 17.92651  ? 134 CYS L SG   1 
ATOM   5312 H H    . CYS B 2 140 ? 54.59600 1.68200   -2.44600  1.000 17.01648  ? 134 CYS L H    1 
ATOM   5313 H HA   . CYS B 2 140 ? 56.50300 3.62700   -2.41900  1.000 16.08890  ? 134 CYS L HA   1 
ATOM   5314 H HB2  . CYS B 2 140 ? 54.60600 4.10000   -3.78500  1.000 17.49531  ? 134 CYS L HB2  1 
ATOM   5315 H HB3  . CYS B 2 140 ? 53.72800 4.08000   -2.46100  1.000 17.49531  ? 134 CYS L HB3  1 
ATOM   5316 N N    . LEU B 2 141 ? 56.50600 3.89500   0.00400   1.000 13.66717  ? 135 LEU L N    1 
ATOM   5317 C CA   . LEU B 2 141 ? 56.56000 3.97900   1.45500   1.000 15.72877  ? 135 LEU L CA   1 
ATOM   5318 C C    . LEU B 2 141 ? 56.44500 5.43200   1.89200   1.000 15.03710  ? 135 LEU L C    1 
ATOM   5319 O O    . LEU B 2 141 ? 57.20100 6.28700   1.42000   1.000 15.43490  ? 135 LEU L O    1 
ATOM   5320 C CB   . LEU B 2 141 ? 57.86400 3.37300   1.97100   1.000 17.38801  ? 135 LEU L CB   1 
ATOM   5321 C CG   . LEU B 2 141 ? 58.21500 3.59600   3.44000   1.000 13.95526  ? 135 LEU L CG   1 
ATOM   5322 C CD1  . LEU B 2 141 ? 57.20200 2.94100   4.36200   1.000 18.20909  ? 135 LEU L CD1  1 
ATOM   5323 C CD2  . LEU B 2 141 ? 59.61100 3.06900   3.71700   1.000 18.80917  ? 135 LEU L CD2  1 
ATOM   5324 H H    . LEU B 2 141 ? 57.20600 4.21600   -0.37900  1.000 16.40418  ? 135 LEU L H    1 
ATOM   5325 H HA   . LEU B 2 141 ? 55.81300 3.49400   1.84000   1.000 18.87809  ? 135 LEU L HA   1 
ATOM   5326 H HB2  . LEU B 2 141 ? 57.81900 2.41400   1.83700   1.000 20.86918  ? 135 LEU L HB2  1 
ATOM   5327 H HB3  . LEU B 2 141 ? 58.59100 3.74800   1.45000   1.000 20.86918  ? 135 LEU L HB3  1 
ATOM   5328 H HG   . LEU B 2 141 ? 58.19300 4.54800   3.62700   1.000 16.74988  ? 135 LEU L HG   1 
ATOM   5329 H HD11 . LEU B 2 141 ? 57.43600 3.14100   5.28100   1.000 21.85448  ? 135 LEU L HD11 1 
ATOM   5330 H HD12 . LEU B 2 141 ? 56.32000 3.29200   4.16200   1.000 21.85448  ? 135 LEU L HD12 1 
ATOM   5331 H HD13 . LEU B 2 141 ? 57.21700 1.98200   4.21700   1.000 21.85448  ? 135 LEU L HD13 1 
ATOM   5332 H HD21 . LEU B 2 141 ? 59.81000 3.18400   4.65900   1.000 22.57458  ? 135 LEU L HD21 1 
ATOM   5333 H HD22 . LEU B 2 141 ? 59.64500 2.12800   3.48300   1.000 22.57458  ? 135 LEU L HD22 1 
ATOM   5334 H HD23 . LEU B 2 141 ? 60.24800 3.56600   3.18100   1.000 22.57458  ? 135 LEU L HD23 1 
ATOM   5335 N N    . LEU B 2 142 ? 55.48600 5.70300   2.77700   1.000 14.34653  ? 136 LEU L N    1 
ATOM   5336 C CA   . LEU B 2 142 ? 55.34600 6.98300   3.46400   1.000 16.45734  ? 136 LEU L CA   1 
ATOM   5337 C C    . LEU B 2 142 ? 55.71900 6.74700   4.92200   1.000 17.36633  ? 136 LEU L C    1 
ATOM   5338 O O    . LEU B 2 142 ? 54.97500 6.08600   5.65400   1.000 18.60809  ? 136 LEU L O    1 
ATOM   5339 C CB   . LEU B 2 142 ? 53.92400 7.51900   3.36300   1.000 17.67845  ? 136 LEU L CB   1 
ATOM   5340 C CG   . LEU B 2 142 ? 53.41000 8.02200   2.02000   1.000 18.04738  ? 136 LEU L CG   1 
ATOM   5341 C CD1  . LEU B 2 142 ? 53.37000 6.92100   0.98500   1.000 19.31957  ? 136 LEU L CD1  1 
ATOM   5342 C CD2  . LEU B 2 142 ? 52.02400 8.61600   2.23100   1.000 22.22955  ? 136 LEU L CD2  1 
ATOM   5343 H H    . LEU B 2 142 ? 54.88000 5.13600   3.00400   1.000 17.21941  ? 136 LEU L H    1 
ATOM   5344 H HA   . LEU B 2 142 ? 55.94400 7.63400   3.06500   1.000 19.75237  ? 136 LEU L HA   1 
ATOM   5345 H HB2  . LEU B 2 142 ? 53.32600 6.80500   3.63500   1.000 21.21771  ? 136 LEU L HB2  1 
ATOM   5346 H HB3  . LEU B 2 142 ? 53.85200 8.26500   3.97900   1.000 21.21771  ? 136 LEU L HB3  1 
ATOM   5347 H HG   . LEU B 2 142 ? 54.01100 8.69900   1.67300   1.000 21.66043  ? 136 LEU L HG   1 
ATOM   5348 H HD11 . LEU B 2 142 ? 52.92700 7.25300   0.18900   1.000 23.18705  ? 136 LEU L HD11 1 
ATOM   5349 H HD12 . LEU B 2 142 ? 54.27800 6.65500   0.77200   1.000 23.18705  ? 136 LEU L HD12 1 
ATOM   5350 H HD13 . LEU B 2 142 ? 52.88000 6.16600   1.34600   1.000 23.18705  ? 136 LEU L HD13 1 
ATOM   5351 H HD21 . LEU B 2 142 ? 51.65800 8.87600   1.37100   1.000 26.67903  ? 136 LEU L HD21 1 
ATOM   5352 H HD22 . LEU B 2 142 ? 51.45400 7.94900   2.64500   1.000 26.67903  ? 136 LEU L HD22 1 
ATOM   5353 H HD23 . LEU B 2 142 ? 52.09800 9.39200   2.80800   1.000 26.67903  ? 136 LEU L HD23 1 
ATOM   5354 N N    . ASN B 2 143 ? 56.85500 7.28100   5.35000   1.000 18.08713  ? 137 ASN L N    1 
ATOM   5355 C CA   . ASN B 2 143 ? 57.39400 6.95300   6.66100   1.000 18.20697  ? 137 ASN L CA   1 
ATOM   5356 C C    . ASN B 2 143 ? 57.20800 8.10700   7.63900   1.000 20.77868  ? 137 ASN L C    1 
ATOM   5357 O O    . ASN B 2 143 ? 57.65100 9.23100   7.37700   1.000 22.20816  ? 137 ASN L O    1 
ATOM   5358 C CB   . ASN B 2 143 ? 58.87300 6.58400   6.56200   1.000 19.87701  ? 137 ASN L CB   1 
ATOM   5359 C CG   . ASN B 2 143 ? 59.26900 5.54200   7.57500   1.000 22.83844  ? 137 ASN L CG   1 
ATOM   5360 O OD1  . ASN B 2 143 ? 58.54300 4.57600   7.79300   1.000 27.12109  ? 137 ASN L OD1  1 
ATOM   5361 N ND2  . ASN B 2 143 ? 60.41100 5.73500   8.21500   1.000 25.28879  ? 137 ASN L ND2  1 
ATOM   5362 H H    . ASN B 2 143 ? 57.33100 7.83600   4.89800   1.000 21.70812  ? 137 ASN L H    1 
ATOM   5363 H HA   . ASN B 2 143 ? 56.89100 6.20000   7.01000   1.000 21.85193  ? 137 ASN L HA   1 
ATOM   5364 H HB2  . ASN B 2 143 ? 59.05400 6.22900   5.67700   1.000 23.85598  ? 137 ASN L HB2  1 
ATOM   5365 H HB3  . ASN B 2 143 ? 59.41000 7.37600   6.71700   1.000 23.85598  ? 137 ASN L HB3  1 
ATOM   5366 H HD21 . ASN B 2 143 ? 60.67700 5.16600   8.80200   1.000 30.35012  ? 137 ASN L HD21 1 
ATOM   5367 H HD22 . ASN B 2 143 ? 60.88800 6.43000   8.04300   1.000 30.35012  ? 137 ASN L HD22 1 
ATOM   5368 N N    . ASN B 2 144 ? 56.54800 7.81900   8.76300   1.000 20.66624  ? 138 ASN L N    1 
ATOM   5369 C CA   . ASN B 2 144 ? 56.55800 8.66700   9.95300   1.000 20.92757  ? 138 ASN L CA   1 
ATOM   5370 C C    . ASN B 2 144 ? 55.94500 10.04600  9.67700   1.000 20.34773  ? 138 ASN L C    1 
ATOM   5371 O O    . ASN B 2 144 ? 56.62200 11.07500  9.70000   1.000 21.56816  ? 138 ASN L O    1 
ATOM   5372 C CB   . ASN B 2 144 ? 57.99000 8.81700   10.48500  1.000 21.29691  ? 138 ASN L CB   1 
ATOM   5373 C CG   . ASN B 2 144 ? 58.59100 7.50200   10.92600  1.000 26.72952  ? 138 ASN L CG   1 
ATOM   5374 O OD1  . ASN B 2 144 ? 57.88000 6.52500   11.16600  1.000 26.28915  ? 138 ASN L OD1  1 
ATOM   5375 N ND2  . ASN B 2 144 ? 59.91200 7.47500   11.05400  1.000 30.39956  ? 138 ASN L ND2  1 
ATOM   5376 H H    . ASN B 2 144 ? 56.07000 7.11200   8.86100   1.000 24.80305  ? 138 ASN L H    1 
ATOM   5377 H HA   . ASN B 2 144 ? 56.00500 8.23600   10.62300  1.000 25.11665  ? 138 ASN L HA   1 
ATOM   5378 H HB2  . ASN B 2 144 ? 58.55100 9.18300   9.78300   1.000 25.55987  ? 138 ASN L HB2  1 
ATOM   5379 H HB3  . ASN B 2 144 ? 57.98200 9.41500   11.24900  1.000 25.55987  ? 138 ASN L HB3  1 
ATOM   5380 H HD21 . ASN B 2 144 ? 60.30500 6.75200   11.30200  1.000 36.48304  ? 138 ASN L HD21 1 
ATOM   5381 H HD22 . ASN B 2 144 ? 60.37500 8.18100   10.88800  1.000 36.48304  ? 138 ASN L HD22 1 
ATOM   5382 N N    . PHE B 2 145 ? 54.63100 10.04200  9.45900   1.000 19.74650  ? 139 PHE L N    1 
ATOM   5383 C CA   . PHE B 2 145 ? 53.89800 11.27000  9.18600   1.000 20.67712  ? 139 PHE L CA   1 
ATOM   5384 C C    . PHE B 2 145 ? 52.68200 11.37600  10.09800  1.000 22.87854  ? 139 PHE L C    1 
ATOM   5385 O O    . PHE B 2 145 ? 52.27900 10.41700  10.76000  1.000 21.31642  ? 139 PHE L O    1 
ATOM   5386 C CB   . PHE B 2 145 ? 53.46100 11.35200  7.71500   1.000 21.12639  ? 139 PHE L CB   1 
ATOM   5387 C CG   . PHE B 2 145 ? 52.48600 10.28400  7.30500   1.000 20.84728  ? 139 PHE L CG   1 
ATOM   5388 C CD1  . PHE B 2 145 ? 52.92700 9.01300   6.97300   1.000 20.75834  ? 139 PHE L CD1  1 
ATOM   5389 C CD2  . PHE B 2 145 ? 51.13000 10.55500  7.23600   1.000 21.68705  ? 139 PHE L CD2  1 
ATOM   5390 C CE1  . PHE B 2 145 ? 52.03100 8.03200   6.59100   1.000 20.85830  ? 139 PHE L CE1  1 
ATOM   5391 C CE2  . PHE B 2 145 ? 50.23100 9.57900   6.85300   1.000 25.34869  ? 139 PHE L CE2  1 
ATOM   5392 C CZ   . PHE B 2 145 ? 50.68300 8.31600   6.52800   1.000 22.63807  ? 139 PHE L CZ   1 
ATOM   5393 H H    . PHE B 2 145 ? 54.14200 9.33500   9.46500   1.000 23.69938  ? 139 PHE L H    1 
ATOM   5394 H HA   . PHE B 2 145 ? 54.48000 12.02200  9.38000   1.000 24.81611  ? 139 PHE L HA   1 
ATOM   5395 H HB2  . PHE B 2 145 ? 53.03700 12.21200  7.56400   1.000 25.35523  ? 139 PHE L HB2  1 
ATOM   5396 H HB3  . PHE B 2 145 ? 54.24600 11.26600  7.15200   1.000 25.35523  ? 139 PHE L HB3  1 
ATOM   5397 H HD1  . PHE B 2 145 ? 53.83500 8.81800   7.00800   1.000 24.91358  ? 139 PHE L HD1  1 
ATOM   5398 H HD2  . PHE B 2 145 ? 50.82100 11.40600  7.44900   1.000 26.02803  ? 139 PHE L HD2  1 
ATOM   5399 H HE1  . PHE B 2 145 ? 52.33800 7.18100   6.37600   1.000 25.03353  ? 139 PHE L HE1  1 
ATOM   5400 H HE2  . PHE B 2 145 ? 49.32200 9.77200   6.81400   1.000 30.42200  ? 139 PHE L HE2  1 
ATOM   5401 H HZ   . PHE B 2 145 ? 50.08000 7.65700   6.26800   1.000 27.16925  ? 139 PHE L HZ   1 
ATOM   5402 N N    . TYR B 2 146 ? 52.10000 12.57800  10.12300  1.000 21.28471  ? 140 TYR L N    1 
ATOM   5403 C CA   . TYR B 2 146 ? 50.91200 12.86400  10.91300  1.000 27.29957  ? 140 TYR L CA   1 
ATOM   5404 C C    . TYR B 2 146 ? 50.22800 14.06200  10.27600  1.000 26.56728  ? 140 TYR L C    1 
ATOM   5405 O O    . TYR B 2 146 ? 50.92700 14.99100  9.85400   1.000 27.10841  ? 140 TYR L O    1 
ATOM   5406 C CB   . TYR B 2 146 ? 51.25800 13.16700  12.37400  1.000 25.63738  ? 140 TYR L CB   1 
ATOM   5407 C CG   . TYR B 2 146 ? 50.04000 13.27800  13.26300  1.000 28.85889  ? 140 TYR L CG   1 
ATOM   5408 C CD1  . TYR B 2 146 ? 49.35000 14.47900  13.38900  1.000 29.15872  ? 140 TYR L CD1  1 
ATOM   5409 C CD2  . TYR B 2 146 ? 49.56800 12.17500  13.96100  1.000 28.86773  ? 140 TYR L CD2  1 
ATOM   5410 C CE1  . TYR B 2 146 ? 48.22600 14.57600  14.19400  1.000 29.64798  ? 140 TYR L CE1  1 
ATOM   5411 C CE2  . TYR B 2 146 ? 48.44600 12.26300  14.76600  1.000 29.38839  ? 140 TYR L CE2  1 
ATOM   5412 C CZ   . TYR B 2 146 ? 47.77900 13.46300  14.87700  1.000 28.86748  ? 140 TYR L CZ   1 
ATOM   5413 O OH   . TYR B 2 146 ? 46.66400 13.55200  15.67800  1.000 33.31957  ? 140 TYR L OH   1 
ATOM   5414 H H    . TYR B 2 146 ? 52.38400 13.25700  9.67800   1.000 25.54523  ? 140 TYR L H    1 
ATOM   5415 H HA   . TYR B 2 146 ? 50.31300 12.10100  10.90300  1.000 32.76305  ? 140 TYR L HA   1 
ATOM   5416 H HB2  . TYR B 2 146 ? 51.81600 12.45300  12.72000  1.000 30.76843  ? 140 TYR L HB2  1 
ATOM   5417 H HB3  . TYR B 2 146 ? 51.73600 14.01100  12.41600  1.000 30.76843  ? 140 TYR L HB3  1 
ATOM   5418 H HD1  . TYR B 2 146 ? 49.64700 15.22800  12.92500  1.000 34.99404  ? 140 TYR L HD1  1 
ATOM   5419 H HD2  . TYR B 2 146 ? 50.01300 11.36200  13.88600  1.000 34.64484  ? 140 TYR L HD2  1 
ATOM   5420 H HE1  . TYR B 2 146 ? 47.77700 15.38600  14.27300  1.000 35.58114  ? 140 TYR L HE1  1 
ATOM   5421 H HE2  . TYR B 2 146 ? 48.14400 11.51500  15.22900  1.000 35.26964  ? 140 TYR L HE2  1 
ATOM   5422 H HH   . TYR B 2 146 ? 46.42800 12.78500  15.92800  1.000 39.98705  ? 140 TYR L HH   1 
ATOM   5423 N N    . PRO B 2 147 ? 48.89100 14.09200  10.19500  1.000 27.97726  ? 141 PRO L N    1 
ATOM   5424 C CA   . PRO B 2 147 ? 47.93600 13.08600  10.66500  1.000 29.94791  ? 141 PRO L CA   1 
ATOM   5425 C C    . PRO B 2 147 ? 47.85400 11.89600  9.71700   1.000 29.60781  ? 141 PRO L C    1 
ATOM   5426 O O    . PRO B 2 147 ? 48.67300 11.77100  8.80600   1.000 24.71524  ? 141 PRO L O    1 
ATOM   5427 C CB   . PRO B 2 147 ? 46.61600 13.85800  10.70200  1.000 32.68831  ? 141 PRO L CB   1 
ATOM   5428 C CG   . PRO B 2 147 ? 46.75200 14.84000  9.58200   1.000 31.14710  ? 141 PRO L CG   1 
ATOM   5429 C CD   . PRO B 2 147 ? 48.21000 15.23500  9.55600   1.000 31.55849  ? 141 PRO L CD   1 
ATOM   5430 H HA   . PRO B 2 147 ? 48.14900 12.77500  11.55800  1.000 35.94106  ? 141 PRO L HA   1 
ATOM   5431 H HB2  . PRO B 2 147 ? 45.87000 13.25600  10.55500  1.000 39.22955  ? 141 PRO L HB2  1 
ATOM   5432 H HB3  . PRO B 2 147 ? 46.51500 14.30900  11.55500  1.000 39.22955  ? 141 PRO L HB3  1 
ATOM   5433 H HG2  . PRO B 2 147 ? 46.49500 14.42100  8.74600   1.000 37.38009  ? 141 PRO L HG2  1 
ATOM   5434 H HG3  . PRO B 2 147 ? 46.19000 15.61200  9.75200   1.000 37.38009  ? 141 PRO L HG3  1 
ATOM   5435 H HD2  . PRO B 2 147 ? 48.51800 15.35200  8.64400   1.000 37.87376  ? 141 PRO L HD2  1 
ATOM   5436 H HD3  . PRO B 2 147 ? 48.35500 16.04900  10.06200  1.000 37.87376  ? 141 PRO L HD3  1 
ATOM   5437 N N    . ARG B 2 148 ? 46.85400 11.04300  9.93200   1.000 32.76823  ? 142 ARG L N    1 
ATOM   5438 C CA   . ARG B 2 148 ? 46.76500 9.79200   9.18800   1.000 32.90864  ? 142 ARG L CA   1 
ATOM   5439 C C    . ARG B 2 148 ? 46.33100 10.00500  7.74300   1.000 31.82780  ? 142 ARG L C    1 
ATOM   5440 O O    . ARG B 2 148 ? 46.67700 9.19900   6.87200   1.000 33.17819  ? 142 ARG L O    1 
ATOM   5441 C CB   . ARG B 2 148 ? 45.80000 8.85100   9.91000   1.000 33.10834  ? 142 ARG L CB   1 
ATOM   5442 C CG   . ARG B 2 148 ? 45.57900 7.52100   9.22800   1.000 38.00846  ? 142 ARG L CG   1 
ATOM   5443 C CD   . ARG B 2 148 ? 45.12400 6.48700   10.24000  1.000 45.85963  ? 142 ARG L CD   1 
ATOM   5444 N NE   . ARG B 2 148 ? 44.52700 5.31400   9.61500   1.000 54.61840  ? 142 ARG L NE   1 
ATOM   5445 C CZ   . ARG B 2 148 ? 43.82400 4.39900   10.26700  1.000 63.22750  ? 142 ARG L CZ   1 
ATOM   5446 N NH1  . ARG B 2 148 ? 43.60000 4.49700   11.56800  1.000 69.09814  ? 142 ARG L NH1  1 
ATOM   5447 N NH2  . ARG B 2 148 ? 43.32800 3.36200   9.59800   1.000 55.64871  ? 142 ARG L NH2  1 
ATOM   5448 H H    . ARG B 2 148 ? 46.21900 11.16400  10.49900  1.000 39.32544  ? 142 ARG L H    1 
ATOM   5449 H HA   . ARG B 2 148 ? 47.64100 9.37700   9.15900   1.000 39.49394  ? 142 ARG L HA   1 
ATOM   5450 H HB2  . ARG B 2 148 ? 46.15200 8.67000   10.79600  1.000 39.73358  ? 142 ARG L HB2  1 
ATOM   5451 H HB3  . ARG B 2 148 ? 44.93700 9.29000   9.98000   1.000 39.73358  ? 142 ARG L HB3  1 
ATOM   5452 H HG2  . ARG B 2 148 ? 44.89400 7.61200   8.54700   1.000 45.61372  ? 142 ARG L HG2  1 
ATOM   5453 H HG3  . ARG B 2 148 ? 46.40800 7.21800   8.82600   1.000 45.61372  ? 142 ARG L HG3  1 
ATOM   5454 H HD2  . ARG B 2 148 ? 45.88900 6.19300   10.75900  1.000 55.03513  ? 142 ARG L HD2  1 
ATOM   5455 H HD3  . ARG B 2 148 ? 44.46000 6.88600   10.82400  1.000 55.03513  ? 142 ARG L HD3  1 
ATOM   5456 H HE   . ARG B 2 148 ? 44.63800 5.20900   8.76800   1.000 65.54566  ? 142 ARG L HE   1 
ATOM   5457 H HH11 . ARG B 2 148 ? 43.91300 5.16500   12.00900  1.000 82.92134  ? 142 ARG L HH11 1 
ATOM   5458 H HH12 . ARG B 2 148 ? 43.14100 3.89200   11.97200  1.000 82.92134  ? 142 ARG L HH12 1 
ATOM   5459 H HH21 . ARG B 2 148 ? 43.46400 3.29200   8.75100   1.000 66.78202  ? 142 ARG L HH21 1 
ATOM   5460 H HH22 . ARG B 2 148 ? 42.87000 2.76200   10.01100  1.000 66.78202  ? 142 ARG L HH22 1 
ATOM   5461 N N    . GLU B 2 149 ? 45.59500 11.07600  7.45900   1.000 34.07793  ? 143 GLU L N    1 
ATOM   5462 C CA   . GLU B 2 149 ? 45.03400 11.26400  6.12600   1.000 37.20757  ? 143 GLU L CA   1 
ATOM   5463 C C    . GLU B 2 149 ? 46.12400 11.65900  5.13800   1.000 34.59860  ? 143 GLU L C    1 
ATOM   5464 O O    . GLU B 2 149 ? 46.81300 12.66700  5.32400   1.000 34.92732  ? 143 GLU L O    1 
ATOM   5465 C CB   . GLU B 2 149 ? 43.93400 12.32100  6.16000   1.000 46.17825  ? 143 GLU L CB   1 
ATOM   5466 C CG   . GLU B 2 149 ? 42.66000 11.85700  6.85700   1.000 62.78811  ? 143 GLU L CG   1 
ATOM   5467 C CD   . GLU B 2 149 ? 41.59800 12.94100  6.92500   1.000 79.55800  ? 143 GLU L CD   1 
ATOM   5468 O OE1  . GLU B 2 149 ? 41.88300 14.08300  6.50400   1.000 80.92761  ? 143 GLU L OE1  1 
ATOM   5469 O OE2  . GLU B 2 149 ? 40.47900 12.65000  7.40100   1.000 79.05807  ? 143 GLU L OE2  1 
ATOM   5470 H H    . GLU B 2 149 ? 45.40800 11.70300  8.01600   1.000 40.89709  ? 143 GLU L H    1 
ATOM   5471 H HA   . GLU B 2 149 ? 44.64700 10.42600  5.82900   1.000 44.65265  ? 143 GLU L HA   1 
ATOM   5472 H HB2  . GLU B 2 149 ? 44.26400 13.10000  6.63400   1.000 55.41747  ? 143 GLU L HB2  1 
ATOM   5473 H HB3  . GLU B 2 149 ? 43.70300 12.56000  5.24900   1.000 55.41747  ? 143 GLU L HB3  1 
ATOM   5474 H HG2  . GLU B 2 149 ? 42.29000 11.10500  6.36900   1.000 75.34930  ? 143 GLU L HG2  1 
ATOM   5475 H HG3  . GLU B 2 149 ? 42.87600 11.59100  7.76400   1.000 75.34930  ? 143 GLU L HG3  1 
ATOM   5476 N N    . ALA B 2 150 ? 46.27500 10.86100  4.08500   1.000 30.39760  ? 144 ALA L N    1 
ATOM   5477 C CA   . ALA B 2 150 ? 47.20000 11.16600  3.00500   1.000 29.32806  ? 144 ALA L CA   1 
ATOM   5478 C C    . ALA B 2 150 ? 46.65600 10.55200  1.72600   1.000 28.03799  ? 144 ALA L C    1 
ATOM   5479 O O    . ALA B 2 150 ? 46.09000 9.45600   1.74800   1.000 32.13889  ? 144 ALA L O    1 
ATOM   5480 C CB   . ALA B 2 150 ? 48.60400 10.63600  3.30000   1.000 32.37892  ? 144 ALA L CB   1 
ATOM   5481 H H    . ALA B 2 150 ? 45.84500 10.12500  3.97300   1.000 36.48070  ? 144 ALA L H    1 
ATOM   5482 H HA   . ALA B 2 150 ? 47.26600 12.12700  2.88500   1.000 35.19724  ? 144 ALA L HA   1 
ATOM   5483 H HB1  . ALA B 2 150 ? 49.18600 10.85200  2.55500   1.000 38.85828  ? 144 ALA L HB1  1 
ATOM   5484 H HB2  . ALA B 2 150 ? 48.93600 11.05300  4.11100   1.000 38.85828  ? 144 ALA L HB2  1 
ATOM   5485 H HB3  . ALA B 2 150 ? 48.56000 9.67400   3.41800   1.000 38.85828  ? 144 ALA L HB3  1 
ATOM   5486 N N    . LYS B 2 151 ? 46.82400 11.26600  0.61900   1.000 26.69787  ? 145 LYS L N    1 
ATOM   5487 C CA   . LYS B 2 151 ? 46.35800 10.82000  -0.68600  1.000 26.24805  ? 145 LYS L CA   1 
ATOM   5488 C C    . LYS B 2 151 ? 47.55700 10.34100  -1.49300  1.000 26.57889  ? 145 LYS L C    1 
ATOM   5489 O O    . LYS B 2 151 ? 48.48000 11.11800  -1.75900  1.000 26.62983  ? 145 LYS L O    1 
ATOM   5490 C CB   . LYS B 2 151 ? 45.63800 11.95300  -1.41500  1.000 28.29874  ? 145 LYS L CB   1 
ATOM   5491 C CG   . LYS B 2 151 ? 44.91700 11.55000  -2.69100  1.000 30.65844  ? 145 LYS L CG   1 
ATOM   5492 C CD   . LYS B 2 151 ? 44.45200 12.79400  -3.44700  1.000 36.61907  ? 145 LYS L CD   1 
ATOM   5493 C CE   . LYS B 2 151 ? 43.45500 12.46100  -4.54000  1.000 43.29860  ? 145 LYS L CE   1 
ATOM   5494 N NZ   . LYS B 2 151 ? 44.01500 11.49900  -5.52600  1.000 60.70803  ? 145 LYS L NZ   1 
ATOM   5495 H H    . LYS B 2 151 ? 47.21500 12.03200  0.60000   1.000 32.04102  ? 145 LYS L H    1 
ATOM   5496 H HA   . LYS B 2 151 ? 45.73900 10.08100  -0.58200  1.000 31.50123  ? 145 LYS L HA   1 
ATOM   5497 H HB2  . LYS B 2 151 ? 44.97600 12.33000  -0.81500  1.000 33.96206  ? 145 LYS L HB2  1 
ATOM   5498 H HB3  . LYS B 2 151 ? 46.29300 12.62800  -1.65400  1.000 33.96206  ? 145 LYS L HB3  1 
ATOM   5499 H HG2  . LYS B 2 151 ? 45.51900 11.04700  -3.26100  1.000 36.79370  ? 145 LYS L HG2  1 
ATOM   5500 H HG3  . LYS B 2 151 ? 44.14000 11.01200  -2.47100  1.000 36.79370  ? 145 LYS L HG3  1 
ATOM   5501 H HD2  . LYS B 2 151 ? 44.02600 13.40400  -2.82500  1.000 43.94646  ? 145 LYS L HD2  1 
ATOM   5502 H HD3  . LYS B 2 151 ? 45.22000 13.22200  -3.85800  1.000 43.94646  ? 145 LYS L HD3  1 
ATOM   5503 H HE2  . LYS B 2 151 ? 42.66500 12.06200  -4.14200  1.000 51.96189  ? 145 LYS L HE2  1 
ATOM   5504 H HE3  . LYS B 2 151 ? 43.21500 13.27300  -5.01200  1.000 51.96189  ? 145 LYS L HE3  1 
ATOM   5505 H HZ1  . LYS B 2 151 ? 43.47300 11.43300  -6.22900  1.000 72.85321  ? 145 LYS L HZ1  1 
ATOM   5506 H HZ2  . LYS B 2 151 ? 44.81400 11.77700  -5.80200  1.000 72.85321  ? 145 LYS L HZ2  1 
ATOM   5507 H HZ3  . LYS B 2 151 ? 44.10200 10.69600  -5.15200  1.000 72.85321  ? 145 LYS L HZ3  1 
ATOM   5508 N N    . VAL B 2 152 ? 47.54100 9.07000   -1.88000  1.000 23.48678  ? 146 VAL L N    1 
ATOM   5509 C CA   . VAL B 2 152 ? 48.60800 8.47300   -2.67200  1.000 21.76614  ? 146 VAL L CA   1 
ATOM   5510 C C    . VAL B 2 152 ? 48.04600 8.15500   -4.04700  1.000 23.58798  ? 146 VAL L C    1 
ATOM   5511 O O    . VAL B 2 152 ? 46.99500 7.51200   -4.16200  1.000 24.35847  ? 146 VAL L O    1 
ATOM   5512 C CB   . VAL B 2 152 ? 49.17800 7.21300   -2.00100  1.000 24.41880  ? 146 VAL L CB   1 
ATOM   5513 C CG1  . VAL B 2 152 ? 50.27900 6.62100   -2.85900  1.000 27.25128  ? 146 VAL L CG1  1 
ATOM   5514 C CG2  . VAL B 2 152 ? 49.70000 7.54500   -0.62000  1.000 24.09884  ? 146 VAL L CG2  1 
ATOM   5515 H H    . VAL B 2 152 ? 46.90700 8.52100   -1.69000  1.000 28.18770  ? 146 VAL L H    1 
ATOM   5516 H HA   . VAL B 2 152 ? 49.33100 9.11200   -2.77200  1.000 26.12293  ? 146 VAL L HA   1 
ATOM   5517 H HB   . VAL B 2 152 ? 48.47400 6.55300   -1.90700  1.000 29.30614  ? 146 VAL L HB   1 
ATOM   5518 H HG11 . VAL B 2 152 ? 50.71100 5.90400   -2.36900  1.000 32.70511  ? 146 VAL L HG11 1 
ATOM   5519 H HG12 . VAL B 2 152 ? 49.88900 6.27400   -3.67700  1.000 32.70511  ? 146 VAL L HG12 1 
ATOM   5520 H HG13 . VAL B 2 152 ? 50.92400 7.31500   -3.06900  1.000 32.70511  ? 146 VAL L HG13 1 
ATOM   5521 H HG21 . VAL B 2 152 ? 50.09800 6.75000   -0.23300  1.000 28.92218  ? 146 VAL L HG21 1 
ATOM   5522 H HG22 . VAL B 2 152 ? 50.36600 8.24600   -0.69400  1.000 28.92218  ? 146 VAL L HG22 1 
ATOM   5523 H HG23 . VAL B 2 152 ? 48.96200 7.84800   -0.06800  1.000 28.92218  ? 146 VAL L HG23 1 
ATOM   5524 N N    . SER B 2 153 ? 48.73700 8.61500   -5.08400  1.000 23.84839  ? 147 SER L N    1 
ATOM   5525 C CA   . SER B 2 153 ? 48.33600 8.39100   -6.46300  1.000 23.75904  ? 147 SER L CA   1 
ATOM   5526 C C    . SER B 2 153 ? 49.50800 7.80600   -7.23300  1.000 20.31762  ? 147 SER L C    1 
ATOM   5527 O O    . SER B 2 153 ? 50.64800 8.25700   -7.08500  1.000 20.31815  ? 147 SER L O    1 
ATOM   5528 C CB   . SER B 2 153 ? 47.87400 9.69200   -7.12700  1.000 27.77954  ? 147 SER L CB   1 
ATOM   5529 O OG   . SER B 2 153 ? 46.84200 10.30700  -6.37500  1.000 29.29844  ? 147 SER L OG   1 
ATOM   5530 H H    . SER B 2 153 ? 49.46200 9.07200   -5.00900  1.000 28.62164  ? 147 SER L H    1 
ATOM   5531 H HA   . SER B 2 153 ? 47.60100 7.76000   -6.49300  1.000 28.51442  ? 147 SER L HA   1 
ATOM   5532 H HB2  . SER B 2 153 ? 48.62700 10.30100  -7.18600  1.000 33.33902  ? 147 SER L HB2  1 
ATOM   5533 H HB3  . SER B 2 153 ? 47.53900 9.49100   -8.01500  1.000 33.33902  ? 147 SER L HB3  1 
ATOM   5534 H HG   . SER B 2 153 ? 47.15500 10.62000  -5.66100  1.000 35.16170  ? 147 SER L HG   1 
ATOM   5535 N N    . TRP B 2 154 ? 49.21900 6.80700   -8.05700  1.000 20.87852  ? 148 TRP L N    1 
ATOM   5536 C CA   . TRP B 2 154 ? 50.21800 6.14700   -8.88100  1.000 19.32801  ? 148 TRP L CA   1 
ATOM   5537 C C    . TRP B 2 154 ? 50.11700 6.61800   -10.32600 1.000 19.05612  ? 148 TRP L C    1 
ATOM   5538 O O    . TRP B 2 154 ? 49.01600 6.74200   -10.87100 1.000 23.43766  ? 148 TRP L O    1 
ATOM   5539 C CB   . TRP B 2 154 ? 50.03100 4.63100   -8.83100  1.000 16.93684  ? 148 TRP L CB   1 
ATOM   5540 C CG   . TRP B 2 154 ? 50.55000 3.97100   -7.59900  1.000 17.53818  ? 148 TRP L CG   1 
ATOM   5541 C CD1  . TRP B 2 154 ? 49.83000 3.56100   -6.51300  1.000 15.98626  ? 148 TRP L CD1  1 
ATOM   5542 C CD2  . TRP B 2 154 ? 51.90900 3.61900   -7.33700  1.000 16.10824  ? 148 TRP L CD2  1 
ATOM   5543 N NE1  . TRP B 2 154 ? 50.66300 2.97900   -5.58800  1.000 16.47742  ? 148 TRP L NE1  1 
ATOM   5544 C CE2  . TRP B 2 154 ? 51.94500 3.00400   -6.07200  1.000 16.06763  ? 148 TRP L CE2  1 
ATOM   5545 C CE3  . TRP B 2 154 ? 53.10100 3.76400   -8.05300  1.000 15.95831  ? 148 TRP L CE3  1 
ATOM   5546 C CZ2  . TRP B 2 154 ? 53.12600 2.53700   -5.50700  1.000 16.22842  ? 148 TRP L CZ2  1 
ATOM   5547 C CZ3  . TRP B 2 154 ? 54.27100 3.30300   -7.48900  1.000 16.03792  ? 148 TRP L CZ3  1 
ATOM   5548 C CH2  . TRP B 2 154 ? 54.27500 2.69400   -6.23100  1.000 14.58645  ? 148 TRP L CH2  1 
ATOM   5549 H H    . TRP B 2 154 ? 48.42700 6.48600   -8.15900  1.000 25.05779  ? 148 TRP L H    1 
ATOM   5550 H HA   . TRP B 2 154 ? 51.10200 6.37100   -8.55100  1.000 23.19718  ? 148 TRP L HA   1 
ATOM   5551 H HB2  . TRP B 2 154 ? 49.08300 4.43700   -8.88700  1.000 20.32778  ? 148 TRP L HB2  1 
ATOM   5552 H HB3  . TRP B 2 154 ? 50.49500 4.23900   -9.58800  1.000 20.32778  ? 148 TRP L HB3  1 
ATOM   5553 H HD1  . TRP B 2 154 ? 48.91100 3.66100   -6.41400  1.000 19.18708  ? 148 TRP L HD1  1 
ATOM   5554 H HE1  . TRP B 2 154 ? 50.42000 2.65300   -4.83000  1.000 19.77648  ? 148 TRP L HE1  1 
ATOM   5555 H HE3  . TRP B 2 154 ? 53.10500 4.16300   -8.89300  1.000 19.15355  ? 148 TRP L HE3  1 
ATOM   5556 H HZ2  . TRP B 2 154 ? 53.13400 2.13400   -4.66800  1.000 19.47768  ? 148 TRP L HZ2  1 
ATOM   5557 H HZ3  . TRP B 2 154 ? 55.07100 3.39900   -7.95400  1.000 19.24907  ? 148 TRP L HZ3  1 
ATOM   5558 H HH2  . TRP B 2 154 ? 55.07900 2.38700   -5.87800  1.000 17.50731  ? 148 TRP L HH2  1 
ATOM   5559 N N    . TYR B 2 155 ? 51.27100 6.85300   -10.95100 1.000 17.08573  ? 149 TYR L N    1 
ATOM   5560 C CA   . TYR B 2 155 ? 51.34500 7.21400   -12.36100 1.000 20.48753  ? 149 TYR L CA   1 
ATOM   5561 C C    . TYR B 2 155 ? 52.32000 6.29100   -13.07700 1.000 19.90800  ? 149 TYR L C    1 
ATOM   5562 O O    . TYR B 2 155 ? 53.42300 6.04300   -12.58300 1.000 20.24757  ? 149 TYR L O    1 
ATOM   5563 C CB   . TYR B 2 155 ? 51.79700 8.66500   -12.54900 1.000 21.50804  ? 149 TYR L CB   1 
ATOM   5564 C CG   . TYR B 2 155 ? 50.81500 9.68900   -12.04900 1.000 23.77770  ? 149 TYR L CG   1 
ATOM   5565 C CD1  . TYR B 2 155 ? 50.85500 10.13400  -10.73700 1.000 24.91821  ? 149 TYR L CD1  1 
ATOM   5566 C CD2  . TYR B 2 155 ? 49.85300 10.22300  -12.89400 1.000 27.59963  ? 149 TYR L CD2  1 
ATOM   5567 C CE1  . TYR B 2 155 ? 49.95700 11.07800  -10.27800 1.000 28.00846  ? 149 TYR L CE1  1 
ATOM   5568 C CE2  . TYR B 2 155 ? 48.95300 11.16500  -12.44500 1.000 27.71825  ? 149 TYR L CE2  1 
ATOM   5569 C CZ   . TYR B 2 155 ? 49.00900 11.59000  -11.13800 1.000 29.89876  ? 149 TYR L CZ   1 
ATOM   5570 O OH   . TYR B 2 155 ? 48.10900 12.53000  -10.69200 1.000 36.39023  ? 149 TYR L OH   1 
ATOM   5571 H H    . TYR B 2 155 ? 52.04000 6.80700   -10.56900 1.000 20.50645  ? 149 TYR L H    1 
ATOM   5572 H HA   . TYR B 2 155 ? 50.46500 7.10400   -12.75300 1.000 24.58861  ? 149 TYR L HA   1 
ATOM   5573 H HB2  . TYR B 2 155 ? 52.62900 8.79500   -12.06700 1.000 25.81322  ? 149 TYR L HB2  1 
ATOM   5574 H HB3  . TYR B 2 155 ? 51.93400 8.82600   -13.49600 1.000 25.81322  ? 149 TYR L HB3  1 
ATOM   5575 H HD1  . TYR B 2 155 ? 51.49600 9.79200   -10.15700 1.000 29.90543  ? 149 TYR L HD1  1 
ATOM   5576 H HD2  . TYR B 2 155 ? 49.81500 9.94000   -13.77900 1.000 33.12313  ? 149 TYR L HD2  1 
ATOM   5577 H HE1  . TYR B 2 155 ? 49.99200 11.36600  -9.39400  1.000 33.61372  ? 149 TYR L HE1  1 
ATOM   5578 H HE2  . TYR B 2 155 ? 48.31100 11.51100  -13.02200 1.000 33.26547  ? 149 TYR L HE2  1 
ATOM   5579 H HH   . TYR B 2 155 ? 47.59500 12.75400  -11.31800 1.000 43.67185  ? 149 TYR L HH   1 
ATOM   5580 N N    . VAL B 2 156 ? 51.92000 5.80300   -14.24500 1.000 19.53529  ? 150 VAL L N    1 
ATOM   5581 C CA   . VAL B 2 156 ? 52.77600 4.98600   -15.09600 1.000 21.56832  ? 150 VAL L CA   1 
ATOM   5582 C C    . VAL B 2 156 ? 52.85000 5.68600   -16.44700 1.000 24.21885  ? 150 VAL L C    1 
ATOM   5583 O O    . VAL B 2 156 ? 51.84300 5.78200   -17.16000 1.000 24.05822  ? 150 VAL L O    1 
ATOM   5584 C CB   . VAL B 2 156 ? 52.25000 3.55100   -15.23100 1.000 22.13870  ? 150 VAL L CB   1 
ATOM   5585 C CG1  . VAL B 2 156 ? 53.19400 2.72000   -16.08200 1.000 23.00848  ? 150 VAL L CG1  1 
ATOM   5586 C CG2  . VAL B 2 156 ? 52.06000 2.91700   -13.84100 1.000 19.71796  ? 150 VAL L CG2  1 
ATOM   5587 H H    . VAL B 2 156 ? 51.13600 5.93400   -14.57400 1.000 23.44591  ? 150 VAL L H    1 
ATOM   5588 H HA   . VAL B 2 156 ? 53.67000 4.94300   -14.72400 1.000 25.88555  ? 150 VAL L HA   1 
ATOM   5589 H HB   . VAL B 2 156 ? 51.38700 3.56900   -15.67200 1.000 26.57001  ? 150 VAL L HB   1 
ATOM   5590 H HG11 . VAL B 2 156 ? 52.87700 1.80400   -16.10200 1.000 27.61375  ? 150 VAL L HG11 1 
ATOM   5591 H HG12 . VAL B 2 156 ? 53.21200 3.08400   -16.98100 1.000 27.61375  ? 150 VAL L HG12 1 
ATOM   5592 H HG13 . VAL B 2 156 ? 54.08300 2.75400   -15.69400 1.000 27.61375  ? 150 VAL L HG13 1 
ATOM   5593 H HG21 . VAL B 2 156 ? 51.75000 2.00500   -13.95000 1.000 23.66512  ? 150 VAL L HG21 1 
ATOM   5594 H HG22 . VAL B 2 156 ? 52.90900 2.92400   -13.37100 1.000 23.66512  ? 150 VAL L HG22 1 
ATOM   5595 H HG23 . VAL B 2 156 ? 51.40400 3.43300   -13.34600 1.000 23.66512  ? 150 VAL L HG23 1 
ATOM   5596 N N    . ASP B 2 157 ? 54.03700 6.18000   -16.79900 1.000 24.44812  ? 151 ASP L N    1 
ATOM   5597 C CA   . ASP B 2 157 ? 54.20600 7.01400   -17.98900 1.000 27.15891  ? 151 ASP L CA   1 
ATOM   5598 C C    . ASP B 2 157 ? 53.15700 8.12200   -18.01100 1.000 29.34065  ? 151 ASP L C    1 
ATOM   5599 O O    . ASP B 2 157 ? 52.51200 8.38400   -19.02900 1.000 25.15750  ? 151 ASP L O    1 
ATOM   5600 C CB   . ASP B 2 157 ? 54.15100 6.17500   -19.26700 1.000 26.96831  ? 151 ASP L CB   1 
ATOM   5601 C CG   . ASP B 2 157 ? 55.39700 5.33300   -19.46500 1.000 27.25891  ? 151 ASP L CG   1 
ATOM   5602 O OD1  . ASP B 2 157 ? 56.48400 5.75800   -19.01900 1.000 25.13821  ? 151 ASP L OD1  1 
ATOM   5603 O OD2  . ASP B 2 157 ? 55.28900 4.24500   -20.06800 1.000 30.33997  ? 151 ASP L OD2  1 
ATOM   5604 H H    . ASP B 2 157 ? 54.76500 6.04700   -16.36100 1.000 29.34131  ? 151 ASP L H    1 
ATOM   5605 H HA   . ASP B 2 157 ? 55.08200 7.43000   -17.95700 1.000 32.59426  ? 151 ASP L HA   1 
ATOM   5606 H HB2  . ASP B 2 157 ? 53.38800 5.57800   -19.22100 1.000 32.36555  ? 151 ASP L HB2  1 
ATOM   5607 H HB3  . ASP B 2 157 ? 54.06300 6.76700   -20.03100 1.000 32.36555  ? 151 ASP L HB3  1 
ATOM   5608 N N    . ASN B 2 158 ? 52.97200 8.75600   -16.85100 1.000 24.40698  ? 152 ASN L N    1 
ATOM   5609 C CA   . ASN B 2 158 ? 52.09500 9.90200   -16.62400 1.000 27.05857  ? 152 ASN L CA   1 
ATOM   5610 C C    . ASN B 2 158 ? 50.61700 9.54700   -16.66400 1.000 26.68898  ? 152 ASN L C    1 
ATOM   5611 O O    . ASN B 2 158 ? 49.77200 10.44400  -16.56800 1.000 28.89008  ? 152 ASN L O    1 
ATOM   5612 C CB   . ASN B 2 158 ? 52.38400 11.02600  -17.62300 1.000 30.75011  ? 152 ASN L CB   1 
ATOM   5613 C CG   . ASN B 2 158 ? 53.82200 11.49400  -17.55800 1.000 30.50872  ? 152 ASN L CG   1 
ATOM   5614 O OD1  . ASN B 2 158 ? 54.37300 11.68300  -16.47500 1.000 31.82986  ? 152 ASN L OD1  1 
ATOM   5615 N ND2  . ASN B 2 158 ? 54.44700 11.65700  -18.71600 1.000 37.27963  ? 152 ASN L ND2  1 
ATOM   5616 H H    . ASN B 2 158 ? 53.37500 8.52000   -16.13000 1.000 29.29194  ? 152 ASN L H    1 
ATOM   5617 H HA   . ASN B 2 158 ? 52.27100 10.23500  -15.73000 1.000 32.47386  ? 152 ASN L HA   1 
ATOM   5618 H HB2  . ASN B 2 158 ? 52.21100 10.70500  -18.52100 1.000 36.90370  ? 152 ASN L HB2  1 
ATOM   5619 H HB3  . ASN B 2 158 ? 51.81100 11.78300  -17.42400 1.000 36.90370  ? 152 ASN L HB3  1 
ATOM   5620 H HD21 . ASN B 2 158 ? 55.26500 11.92100  -18.73000 1.000 44.73913  ? 152 ASN L HD21 1 
ATOM   5621 H HD22 . ASN B 2 158 ? 54.03400 11.49800  -19.45400 1.000 44.73913  ? 152 ASN L HD22 1 
ATOM   5622 N N    . ALA B 2 159 ? 50.27600 8.26900   -16.77800 1.000 24.89889  ? 153 ALA L N    1 
ATOM   5623 C CA   . ALA B 2 159 ? 48.88600 7.83400   -16.76100 1.000 24.06873  ? 153 ALA L CA   1 
ATOM   5624 C C    . ALA B 2 159 ? 48.48600 7.50600   -15.32800 1.000 23.09782  ? 153 ALA L C    1 
ATOM   5625 O O    . ALA B 2 159 ? 49.05600 6.59900   -14.71300 1.000 23.20921  ? 153 ALA L O    1 
ATOM   5626 C CB   . ALA B 2 159 ? 48.69100 6.62200   -17.67000 1.000 23.85883  ? 153 ALA L CB   1 
ATOM   5627 H H    . ALA B 2 159 ? 50.83900 7.62600   -16.86800 1.000 29.88223  ? 153 ALA L H    1 
ATOM   5628 H HA   . ALA B 2 159 ? 48.31500 8.54900   -17.08500 1.000 28.88605  ? 153 ALA L HA   1 
ATOM   5629 H HB1  . ALA B 2 159 ? 47.76300 6.34100   -17.62800 1.000 28.63417  ? 153 ALA L HB1  1 
ATOM   5630 H HB2  . ALA B 2 159 ? 48.92100 6.86900   -18.58000 1.000 28.63417  ? 153 ALA L HB2  1 
ATOM   5631 H HB3  . ALA B 2 159 ? 49.26800 5.90400   -17.36600 1.000 28.63417  ? 153 ALA L HB3  1 
ATOM   5632 N N    . LEU B 2 160 ? 47.51400 8.24600   -14.79800 1.000 23.90798  ? 154 LEU L N    1 
ATOM   5633 C CA   . LEU B 2 160 ? 47.02500 7.98400   -13.45000 1.000 24.57868  ? 154 LEU L CA   1 
ATOM   5634 C C    . LEU B 2 160 ? 46.42500 6.58700   -13.37200 1.000 27.69061  ? 154 LEU L C    1 
ATOM   5635 O O    . LEU B 2 160 ? 45.63200 6.18900   -14.23000 1.000 26.32882  ? 154 LEU L O    1 
ATOM   5636 C CB   . LEU B 2 160 ? 45.98300 9.02800   -13.05600 1.000 25.26904  ? 154 LEU L CB   1 
ATOM   5637 C CG   . LEU B 2 160 ? 45.30800 8.85700   -11.69500 1.000 27.96995  ? 154 LEU L CG   1 
ATOM   5638 C CD1  . LEU B 2 160 ? 46.29500 9.07600   -10.56700 1.000 26.23825  ? 154 LEU L CD1  1 
ATOM   5639 C CD2  . LEU B 2 160 ? 44.13300 9.81200   -11.57100 1.000 27.21927  ? 154 LEU L CD2  1 
ATOM   5640 H H    . LEU B 2 160 ? 47.12400 8.90100   -15.19600 1.000 28.69314  ? 154 LEU L H    1 
ATOM   5641 H HA   . LEU B 2 160 ? 47.76200 8.04000   -12.82300 1.000 29.49798  ? 154 LEU L HA   1 
ATOM   5642 H HB2  . LEU B 2 160 ? 46.41700 9.89500   -13.05000 1.000 30.32642  ? 154 LEU L HB2  1 
ATOM   5643 H HB3  . LEU B 2 160 ? 45.27900 9.01400   -13.72400 1.000 30.32642  ? 154 LEU L HB3  1 
ATOM   5644 H HG   . LEU B 2 160 ? 44.97700 7.94800   -11.62000 1.000 33.56751  ? 154 LEU L HG   1 
ATOM   5645 H HD11 . LEU B 2 160 ? 45.83800 8.95600   -9.72000  1.000 31.48948  ? 154 LEU L HD11 1 
ATOM   5646 H HD12 . LEU B 2 160 ? 47.01600 8.43100   -10.64800 1.000 31.48948  ? 154 LEU L HD12 1 
ATOM   5647 H HD13 . LEU B 2 160 ? 46.64900 9.97700   -10.62700 1.000 31.48948  ? 154 LEU L HD13 1 
ATOM   5648 H HD21 . LEU B 2 160 ? 43.70800 9.68100   -10.70900 1.000 32.66670  ? 154 LEU L HD21 1 
ATOM   5649 H HD22 . LEU B 2 160 ? 44.45700 10.72400  -11.64400 1.000 32.66670  ? 154 LEU L HD22 1 
ATOM   5650 H HD23 . LEU B 2 160 ? 43.50000 9.62900   -12.28200 1.000 32.66670  ? 154 LEU L HD23 1 
ATOM   5651 N N    . GLN B 2 161 ? 46.79900 5.84600   -12.33500 1.000 26.58965  ? 155 GLN L N    1 
ATOM   5652 C CA   . GLN B 2 161 ? 46.32300 4.48500   -12.14900 1.000 26.27872  ? 155 GLN L CA   1 
ATOM   5653 C C    . GLN B 2 161 ? 45.10600 4.46100   -11.23800 1.000 27.33835  ? 155 GLN L C    1 
ATOM   5654 O O    . GLN B 2 161 ? 44.96300 5.28800   -10.33400 1.000 27.98873  ? 155 GLN L O    1 
ATOM   5655 C CB   . GLN B 2 161 ? 47.42400 3.60700   -11.55700 1.000 23.54762  ? 155 GLN L CB   1 
ATOM   5656 C CG   . GLN B 2 161 ? 48.65300 3.55000   -12.41800 1.000 22.35791  ? 155 GLN L CG   1 
ATOM   5657 C CD   . GLN B 2 161 ? 48.35600 2.96300   -13.77600 1.000 23.51790  ? 155 GLN L CD   1 
ATOM   5658 O OE1  . GLN B 2 161 ? 48.11000 1.76400   -13.90300 1.000 24.10876  ? 155 GLN L OE1  1 
ATOM   5659 N NE2  . GLN B 2 161 ? 48.35500 3.80600   -14.79900 1.000 25.12961  ? 155 GLN L NE2  1 
ATOM   5660 H H    . GLN B 2 161 ? 47.33500 6.11500   -11.71800 1.000 31.91115  ? 155 GLN L H    1 
ATOM   5661 H HA   . GLN B 2 161 ? 46.06600 4.11700   -13.00900 1.000 31.53803  ? 155 GLN L HA   1 
ATOM   5662 H HB2  . GLN B 2 161 ? 47.68000 3.96400   -10.69200 1.000 28.26072  ? 155 GLN L HB2  1 
ATOM   5663 H HB3  . GLN B 2 161 ? 47.08600 2.70400   -11.45600 1.000 28.26072  ? 155 GLN L HB3  1 
ATOM   5664 H HG2  . GLN B 2 161 ? 48.99800 4.44800   -12.54400 1.000 26.83306  ? 155 GLN L HG2  1 
ATOM   5665 H HG3  . GLN B 2 161 ? 49.32100 2.99500   -11.98600 1.000 26.83306  ? 155 GLN L HG3  1 
ATOM   5666 H HE21 . GLN B 2 161 ? 48.51900 4.64000   -14.66900 1.000 30.15910  ? 155 GLN L HE21 1 
ATOM   5667 H HE22 . GLN B 2 161 ? 48.19100 3.51900   -15.59300 1.000 30.15910  ? 155 GLN L HE22 1 
ATOM   5668 N N    . SER B 2 162 ? 44.23200 3.48900   -11.47800 1.000 28.05795  ? 156 SER L N    1 
ATOM   5669 C CA   . SER B 2 162 ? 43.00400 3.34400   -10.71200 1.000 29.71722  ? 156 SER L CA   1 
ATOM   5670 C C    . SER B 2 162 ? 42.70300 1.86500   -10.54000 1.000 28.29856  ? 156 SER L C    1 
ATOM   5671 O O    . SER B 2 162 ? 42.73800 1.10700   -11.51400 1.000 28.68900  ? 156 SER L O    1 
ATOM   5672 C CB   . SER B 2 162 ? 41.83400 4.04800   -11.41000 1.000 34.35827  ? 156 SER L CB   1 
ATOM   5673 O OG   . SER B 2 162 ? 40.65400 3.97600   -10.63200 1.000 39.74865  ? 156 SER L OG   1 
ATOM   5674 H H    . SER B 2 162 ? 44.33100 2.89300   -12.09000 1.000 33.67311  ? 156 SER L H    1 
ATOM   5675 H HA   . SER B 2 162 ? 43.11600 3.73600   -9.83100  1.000 35.66424  ? 156 SER L HA   1 
ATOM   5676 H HB2  . SER B 2 162 ? 42.06500 4.98100   -11.54600 1.000 41.23349  ? 156 SER L HB2  1 
ATOM   5677 H HB3  . SER B 2 162 ? 41.67400 3.61900   -12.26500 1.000 41.23349  ? 156 SER L HB3  1 
ATOM   5678 H HG   . SER B 2 162 ? 40.02800 4.37800   -11.02100 1.000 47.70195  ? 156 SER L HG   1 
ATOM   5679 N N    . GLY B 2 163 ? 42.43400 1.45500   -9.30300  1.000 27.47844  ? 157 GLY L N    1 
ATOM   5680 C CA   . GLY B 2 163 ? 41.93700 0.12500   -9.02800  1.000 26.20821  ? 157 GLY L CA   1 
ATOM   5681 C C    . GLY B 2 163 ? 42.97300 -0.97200  -8.95100  1.000 26.36908  ? 157 GLY L C    1 
ATOM   5682 O O    . GLY B 2 163 ? 42.59600 -2.13800  -8.77300  1.000 27.41969  ? 157 GLY L O    1 
ATOM   5683 H H    . GLY B 2 163 ? 42.53400 1.94200   -8.60100  1.000 32.97770  ? 157 GLY L H    1 
ATOM   5684 H HA2  . GLY B 2 163 ? 41.47100 0.14400   -8.17800  1.000 31.45342  ? 157 GLY L HA2  1 
ATOM   5685 H HA3  . GLY B 2 163 ? 41.31000 -0.11700  -9.72700  1.000 31.45342  ? 157 GLY L HA3  1 
ATOM   5686 N N    . ASN B 2 164 ? 44.26000 -0.65300  -9.07100  1.000 25.04866  ? 158 ASN L N    1 
ATOM   5687 C CA   . ASN B 2 164 ? 45.30500 -1.66800  -9.04100  1.000 22.80776  ? 158 ASN L CA   1 
ATOM   5688 C C    . ASN B 2 164 ? 46.32200 -1.41600  -7.93000  1.000 22.55928  ? 158 ASN L C    1 
ATOM   5689 O O    . ASN B 2 164 ? 47.47300 -1.84300  -8.03200  1.000 19.84701  ? 158 ASN L O    1 
ATOM   5690 C CB   . ASN B 2 164 ? 46.00600 -1.76200  -10.39800 1.000 21.77777  ? 158 ASN L CB   1 
ATOM   5691 C CG   . ASN B 2 164 ? 46.54300 -0.42800  -10.87800 1.000 22.34798  ? 158 ASN L CG   1 
ATOM   5692 O OD1  . ASN B 2 164 ? 46.41000 0.59100   -10.20300 1.000 24.39918  ? 158 ASN L OD1  1 
ATOM   5693 N ND2  . ASN B 2 164 ? 47.16700 -0.43200  -12.04800 1.000 21.12733  ? 158 ASN L ND2  1 
ATOM   5694 H H    . ASN B 2 164 ? 44.55200 0.15000   -9.17100  1.000 30.06196  ? 158 ASN L H    1 
ATOM   5695 H HA   . ASN B 2 164 ? 44.88500 -2.52200  -8.85600  1.000 27.37289  ? 158 ASN L HA   1 
ATOM   5696 H HB2  . ASN B 2 164 ? 46.75200 -2.37700  -10.32600 1.000 26.13690  ? 158 ASN L HB2  1 
ATOM   5697 H HB3  . ASN B 2 164 ? 45.37300 -2.08400  -11.05900 1.000 26.13690  ? 158 ASN L HB3  1 
ATOM   5698 H HD21 . ASN B 2 164 ? 47.49000 0.29800   -12.36600 1.000 25.35636  ? 158 ASN L HD21 1 
ATOM   5699 H HD22 . ASN B 2 164 ? 47.24700 -1.16600  -12.49000 1.000 25.35636  ? 158 ASN L HD22 1 
ATOM   5700 N N    . SER B 2 165 ? 45.91500 -0.75200  -6.85100  1.000 22.44826  ? 159 SER L N    1 
ATOM   5701 C CA   . SER B 2 165 ? 46.78800 -0.55600  -5.70400  1.000 18.12574  ? 159 SER L CA   1 
ATOM   5702 C C    . SER B 2 165 ? 46.03400 -0.84600  -4.41500  1.000 20.58737  ? 159 SER L C    1 
ATOM   5703 O O    . SER B 2 165 ? 44.80600 -0.73700  -4.35400  1.000 21.81758  ? 159 SER L O    1 
ATOM   5704 C CB   . SER B 2 165 ? 47.36000 0.86700   -5.66500  1.000 21.25826  ? 159 SER L CB   1 
ATOM   5705 O OG   . SER B 2 165 ? 46.32300 1.82900   -5.65100  1.000 19.99792  ? 159 SER L OG   1 
ATOM   5706 H H    . SER B 2 165 ? 45.13300 -0.40500  -6.76200  1.000 26.94148  ? 159 SER L H    1 
ATOM   5707 H HA   . SER B 2 165 ? 47.52900 -1.18000  -5.76000  1.000 21.75446  ? 159 SER L HA   1 
ATOM   5708 H HB2  . SER B 2 165 ? 47.89600 0.96900   -4.86300  1.000 25.51348  ? 159 SER L HB2  1 
ATOM   5709 H HB3  . SER B 2 165 ? 47.90900 1.00700   -6.45200  1.000 25.51348  ? 159 SER L HB3  1 
ATOM   5710 H HG   . SER B 2 165 ? 45.95500 1.86600   -6.40500  1.000 24.00107  ? 159 SER L HG   1 
ATOM   5711 N N    . GLN B 2 166 ? 46.79000 -1.23100  -3.38900  1.000 19.66701  ? 160 GLN L N    1 
ATOM   5712 C CA   . GLN B 2 166 ? 46.26900 -1.47000  -2.05100  1.000 20.22705  ? 160 GLN L CA   1 
ATOM   5713 C C    . GLN B 2 166 ? 47.18000 -0.80000  -1.03300  1.000 20.05739  ? 160 GLN L C    1 
ATOM   5714 O O    . GLN B 2 166 ? 48.40500 -0.79500  -1.19200  1.000 19.40724  ? 160 GLN L O    1 
ATOM   5715 C CB   . GLN B 2 166 ? 46.17300 -2.96400  -1.74000  1.000 22.56811  ? 160 GLN L CB   1 
ATOM   5716 C CG   . GLN B 2 166 ? 45.01300 -3.67800  -2.39800  1.000 26.35928  ? 160 GLN L CG   1 
ATOM   5717 C CD   . GLN B 2 166 ? 44.93600 -5.13300  -1.98200  1.000 26.97832  ? 160 GLN L CD   1 
ATOM   5718 O OE1  . GLN B 2 166 ? 45.89800 -5.88300  -2.13900  1.000 25.15829  ? 160 GLN L OE1  1 
ATOM   5719 N NE2  . GLN B 2 166 ? 43.79800 -5.53400  -1.42700  1.000 24.96756  ? 160 GLN L NE2  1 
ATOM   5720 H H    . GLN B 2 166 ? 47.63700 -1.36600  -3.44800  1.000 23.60399  ? 160 GLN L H    1 
ATOM   5721 H HA   . GLN B 2 166 ? 45.38000 -1.08700  -1.98000  1.000 24.27604  ? 160 GLN L HA   1 
ATOM   5722 H HB2  . GLN B 2 166 ? 46.98900 -3.39400  -2.04100  1.000 27.08530  ? 160 GLN L HB2  1 
ATOM   5723 H HB3  . GLN B 2 166 ? 46.07500 -3.07300  -0.78100  1.000 27.08530  ? 160 GLN L HB3  1 
ATOM   5724 H HG2  . GLN B 2 166 ? 44.18400 -3.24400  -2.14100  1.000 31.63470  ? 160 GLN L HG2  1 
ATOM   5725 H HG3  . GLN B 2 166 ? 45.12200 -3.64200  -3.36100  1.000 31.63470  ? 160 GLN L HG3  1 
ATOM   5726 H HE21 . GLN B 2 166 ? 43.15200 -4.97600  -1.32000  1.000 29.96465  ? 160 GLN L HE21 1 
ATOM   5727 H HE22 . GLN B 2 166 ? 43.70700 -6.35100  -1.17400  1.000 29.96465  ? 160 GLN L HE22 1 
ATOM   5728 N N    . GLU B 2 167 ? 46.58000 -0.25100  0.01900   1.000 22.45817  ? 161 GLU L N    1 
ATOM   5729 C CA   . GLU B 2 167 ? 47.30700 0.47300   1.04800   1.000 22.56838  ? 161 GLU L CA   1 
ATOM   5730 C C    . GLU B 2 167 ? 47.21200 -0.25500  2.38200   1.000 20.67727  ? 161 GLU L C    1 
ATOM   5731 O O    . GLU B 2 167 ? 46.22800 -0.94200  2.66800   1.000 19.70576  ? 161 GLU L O    1 
ATOM   5732 C CB   . GLU B 2 167 ? 46.76500 1.90000   1.21300   1.000 22.80668  ? 161 GLU L CB   1 
ATOM   5733 C CG   . GLU B 2 167 ? 46.94900 2.79100   -0.00100  1.000 28.03913  ? 161 GLU L CG   1 
ATOM   5734 C CD   . GLU B 2 167 ? 46.47000 4.20900   0.24800   1.000 31.98793  ? 161 GLU L CD   1 
ATOM   5735 O OE1  . GLU B 2 167 ? 45.98500 4.48100   1.36500   1.000 35.53789  ? 161 GLU L OE1  1 
ATOM   5736 O OE2  . GLU B 2 167 ? 46.57700 5.05200   -0.66900  1.000 33.84904  ? 161 GLU L OE2  1 
ATOM   5737 H H    . GLU B 2 167 ? 45.73200 -0.28700  0.15900   1.000 26.95337  ? 161 GLU L H    1 
ATOM   5738 H HA   . GLU B 2 167 ? 48.24300 0.52000   0.79600   1.000 27.08563  ? 161 GLU L HA   1 
ATOM   5739 H HB2  . GLU B 2 167 ? 45.81400 1.84900   1.39700   1.000 27.37158  ? 161 GLU L HB2  1 
ATOM   5740 H HB3  . GLU B 2 167 ? 47.22500 2.32000   1.95700   1.000 27.37158  ? 161 GLU L HB3  1 
ATOM   5741 H HG2  . GLU B 2 167 ? 47.89100 2.82600   -0.23000  1.000 33.65053  ? 161 GLU L HG2  1 
ATOM   5742 H HG3  . GLU B 2 167 ? 46.44000 2.42700   -0.74300  1.000 33.65053  ? 161 GLU L HG3  1 
ATOM   5743 N N    . SER B 2 168 ? 48.24800 -0.08600  3.19900   1.000 18.54566  ? 162 SER L N    1 
ATOM   5744 C CA   . SER B 2 168 ? 48.26200 -0.56500  4.57300   1.000 21.70903  ? 162 SER L CA   1 
ATOM   5745 C C    . SER B 2 168 ? 48.92700 0.49600   5.43600   1.000 20.48814  ? 162 SER L C    1 
ATOM   5746 O O    . SER B 2 168 ? 49.85000 1.18300   4.99700   1.000 17.81394  ? 162 SER L O    1 
ATOM   5747 C CB   . SER B 2 168 ? 49.00200 -1.89800  4.68800   1.000 21.19838  ? 162 SER L CB   1 
ATOM   5748 O OG   . SER B 2 168 ? 48.90300 -2.41700  5.99600   1.000 21.39887  ? 162 SER L OG   1 
ATOM   5749 H H    . SER B 2 168 ? 48.97400 0.31400   2.97200   1.000 22.25836  ? 162 SER L H    1 
ATOM   5750 H HA   . SER B 2 168 ? 47.35900 -0.70400  4.89800   1.000 26.05441  ? 162 SER L HA   1 
ATOM   5751 H HB2  . SER B 2 168 ? 48.60900 -2.53100  4.06700   1.000 25.44162  ? 162 SER L HB2  1 
ATOM   5752 H HB3  . SER B 2 168 ? 49.93800 -1.75900  4.47400   1.000 25.44162  ? 162 SER L HB3  1 
ATOM   5753 H HG   . SER B 2 168 ? 49.27600 -3.16800  6.03600   1.000 25.68222  ? 162 SER L HG   1 
ATOM   5754 N N    . VAL B 2 169 ? 48.45200 0.63100   6.67200   1.000 20.25803  ? 163 VAL L N    1 
ATOM   5755 C CA   . VAL B 2 169 ? 48.88200 1.71200   7.55000   1.000 21.61848  ? 163 VAL L CA   1 
ATOM   5756 C C    . VAL B 2 169 ? 49.19500 1.12700   8.91700   1.000 21.96848  ? 163 VAL L C    1 
ATOM   5757 O O    . VAL B 2 169 ? 48.42400 0.31700   9.44200   1.000 23.13816  ? 163 VAL L O    1 
ATOM   5758 C CB   . VAL B 2 169 ? 47.81200 2.81500   7.66200   1.000 22.91830  ? 163 VAL L CB   1 
ATOM   5759 C CG1  . VAL B 2 169 ? 48.36100 4.02300   8.40100   1.000 25.98978  ? 163 VAL L CG1  1 
ATOM   5760 C CG2  . VAL B 2 169 ? 47.32700 3.21900   6.28500   1.000 25.34978  ? 163 VAL L CG2  1 
ATOM   5761 H H    . VAL B 2 169 ? 47.87300 0.10200   7.02600   1.000 24.31321  ? 163 VAL L H    1 
ATOM   5762 H HA   . VAL B 2 169 ? 49.69400 2.10800   7.19800   1.000 25.94574  ? 163 VAL L HA   1 
ATOM   5763 H HB   . VAL B 2 169 ? 47.05900 2.46700   8.16600   1.000 27.50553  ? 163 VAL L HB   1 
ATOM   5764 H HG11 . VAL B 2 169 ? 47.67700 4.71000   8.43600   1.000 31.19130  ? 163 VAL L HG11 1 
ATOM   5765 H HG12 . VAL B 2 169 ? 48.60900 3.75700   9.30000   1.000 31.19130  ? 163 VAL L HG12 1 
ATOM   5766 H HG13 . VAL B 2 169 ? 49.13900 4.35500   7.92800   1.000 31.19130  ? 163 VAL L HG13 1 
ATOM   5767 H HG21 . VAL B 2 169 ? 46.77200 4.01000   6.36500   1.000 30.42330  ? 163 VAL L HG21 1 
ATOM   5768 H HG22 . VAL B 2 169 ? 48.09500 3.41000   5.72300   1.000 30.42330  ? 163 VAL L HG22 1 
ATOM   5769 H HG23 . VAL B 2 169 ? 46.81200 2.49100   5.90400   1.000 30.42330  ? 163 VAL L HG23 1 
ATOM   5770 N N    . THR B 2 170 ? 50.33600 1.51400   9.47600   1.000 20.59565  ? 164 THR L N    1 
ATOM   5771 C CA   . THR B 2 170 ? 50.64700 1.14400   10.84300  1.000 22.80747  ? 164 THR L CA   1 
ATOM   5772 C C    . THR B 2 170 ? 49.80000 1.97500   11.80400  1.000 25.43731  ? 164 THR L C    1 
ATOM   5773 O O    . THR B 2 170 ? 49.17100 2.96800   11.42900  1.000 26.84913  ? 164 THR L O    1 
ATOM   5774 C CB   . THR B 2 170 ? 52.13200 1.34600   11.13700  1.000 21.50631  ? 164 THR L CB   1 
ATOM   5775 O OG1  . THR B 2 170 ? 52.47800 2.72500   10.95000  1.000 23.89843  ? 164 THR L OG1  1 
ATOM   5776 C CG2  . THR B 2 170 ? 52.98300 0.47400   10.22300  1.000 24.73991  ? 164 THR L CG2  1 
ATOM   5777 H H    . THR B 2 170 ? 50.94000 1.98700   9.08600   1.000 24.71835  ? 164 THR L H    1 
ATOM   5778 H HA   . THR B 2 170 ? 50.44500 0.20400   10.97800  1.000 27.37253  ? 164 THR L HA   1 
ATOM   5779 H HB   . THR B 2 170 ? 52.31800 1.09300   12.05500  1.000 25.81115  ? 164 THR L HB   1 
ATOM   5780 H HG1  . THR B 2 170 ? 52.10200 3.19800   11.53300  1.000 28.68168  ? 164 THR L HG1  1 
ATOM   5781 H HG21 . THR B 2 170 ? 53.92300 0.59200   10.43300  1.000 29.69146  ? 164 THR L HG21 1 
ATOM   5782 H HG22 . THR B 2 170 ? 52.74800 -0.45900  10.34300  1.000 29.69146  ? 164 THR L HG22 1 
ATOM   5783 H HG23 . THR B 2 170 ? 52.83300 0.72000   9.29700   1.000 29.69146  ? 164 THR L HG23 1 
ATOM   5784 N N    . GLU B 2 171 ? 49.77000 1.55300   13.05700  1.000 28.79780  ? 165 GLU L N    1 
ATOM   5785 C CA   . GLU B 2 171 ? 49.11900 2.35200   14.08200  1.000 31.87789  ? 165 GLU L CA   1 
ATOM   5786 C C    . GLU B 2 171 ? 50.12600 3.34700   14.65100  1.000 25.69612  ? 165 GLU L C    1 
ATOM   5787 O O    . GLU B 2 171 ? 51.32600 3.27900   14.37800  1.000 23.49565  ? 165 GLU L O    1 
ATOM   5788 C CB   . GLU B 2 171 ? 48.52000 1.44700   15.15800  1.000 34.97825  ? 165 GLU L CB   1 
ATOM   5789 C CG   . GLU B 2 171 ? 47.49900 0.46200   14.57700  1.000 38.70791  ? 165 GLU L CG   1 
ATOM   5790 C CD   . GLU B 2 171 ? 46.57800 -0.15000  15.61300  1.000 46.91859  ? 165 GLU L CD   1 
ATOM   5791 O OE1  . GLU B 2 171 ? 47.07700 -0.65800  16.63700  1.000 49.86749  ? 165 GLU L OE1  1 
ATOM   5792 O OE2  . GLU B 2 171 ? 45.34700 -0.12500  15.39700  1.000 52.99909  ? 165 GLU L OE2  1 
ATOM   5793 H H    . GLU B 2 171 ? 50.11600 0.81700   13.33600  1.000 34.56092  ? 165 GLU L H    1 
ATOM   5794 H HA   . GLU B 2 171 ? 48.37900 2.85800   13.71000  1.000 38.25704  ? 165 GLU L HA   1 
ATOM   5795 H HB2  . GLU B 2 171 ? 49.23100 0.93600   15.57600  1.000 41.97747  ? 165 GLU L HB2  1 
ATOM   5796 H HB3  . GLU B 2 171 ? 48.07100 1.99400   15.82100  1.000 41.97747  ? 165 GLU L HB3  1 
ATOM   5797 H HG2  . GLU B 2 171 ? 46.94700 0.93000   13.93100  1.000 46.45306  ? 165 GLU L HG2  1 
ATOM   5798 H HG3  . GLU B 2 171 ? 47.97700 -0.26200  14.14200  1.000 46.45306  ? 165 GLU L HG3  1 
ATOM   5799 N N    . GLN B 2 172 ? 49.62400 4.30500   15.42600  1.000 29.59932  ? 166 GLN L N    1 
ATOM   5800 C CA   . GLN B 2 172 ? 50.49200 5.35100   15.95000  1.000 26.76817  ? 166 GLN L CA   1 
ATOM   5801 C C    . GLN B 2 172 ? 51.70300 4.73900   16.64200  1.000 26.16763  ? 166 GLN L C    1 
ATOM   5802 O O    . GLN B 2 172 ? 51.57200 3.84700   17.48400  1.000 26.99762  ? 166 GLN L O    1 
ATOM   5803 C CB   . GLN B 2 172 ? 49.72200 6.25200   16.91600  1.000 26.82790  ? 166 GLN L CB   1 
ATOM   5804 C CG   . GLN B 2 172 ? 48.68300 7.12700   16.23400  1.000 28.20781  ? 166 GLN L CG   1 
ATOM   5805 C CD   . GLN B 2 172 ? 48.25200 8.30800   17.08900  1.000 31.76969  ? 166 GLN L CD   1 
ATOM   5806 O OE1  . GLN B 2 172 ? 47.22400 8.25900   17.76600  1.000 32.54910  ? 166 GLN L OE1  1 
ATOM   5807 N NE2  . GLN B 2 172 ? 49.03500 9.38000   17.05400  1.000 27.58687  ? 166 GLN L NE2  1 
ATOM   5808 H H    . GLN B 2 172 ? 48.79900 4.36900   15.65900  1.000 35.52276  ? 166 GLN L H    1 
ATOM   5809 H HA   . GLN B 2 172 ? 50.80300 5.90400   15.21600  1.000 32.12538  ? 166 GLN L HA   1 
ATOM   5810 H HB2  . GLN B 2 172 ? 49.26300 5.69500   17.56400  1.000 32.19706  ? 166 GLN L HB2  1 
ATOM   5811 H HB3  . GLN B 2 172 ? 50.35200 6.83600   17.36800  1.000 32.19706  ? 166 GLN L HB3  1 
ATOM   5812 H HG2  . GLN B 2 172 ? 49.05600 7.47600   15.40900  1.000 33.85294  ? 166 GLN L HG2  1 
ATOM   5813 H HG3  . GLN B 2 172 ? 47.89600 6.59300   16.04300  1.000 33.85294  ? 166 GLN L HG3  1 
ATOM   5814 H HE21 . GLN B 2 172 ? 49.74200 9.38000   16.56500  1.000 33.10781  ? 166 GLN L HE21 1 
ATOM   5815 H HE22 . GLN B 2 172 ? 48.83400 10.07400  17.52000  1.000 33.10781  ? 166 GLN L HE22 1 
ATOM   5816 N N    . ASP B 2 173 ? 52.88500 5.21300   16.25800  1.000 22.46459  ? 167 ASP L N    1 
ATOM   5817 C CA   . ASP B 2 173 ? 54.12200 4.77200   16.88500  1.000 24.85535  ? 167 ASP L CA   1 
ATOM   5818 C C    . ASP B 2 173 ? 54.14100 5.16200   18.35700  1.000 30.65893  ? 167 ASP L C    1 
ATOM   5819 O O    . ASP B 2 173 ? 53.77700 6.28200   18.72400  1.000 25.96628  ? 167 ASP L O    1 
ATOM   5820 C CB   . ASP B 2 173 ? 55.31400 5.39100   16.15500  1.000 27.26691  ? 167 ASP L CB   1 
ATOM   5821 C CG   . ASP B 2 173 ? 56.64400 4.96200   16.73600  1.000 34.45870  ? 167 ASP L CG   1 
ATOM   5822 O OD1  . ASP B 2 173 ? 57.11400 3.85400   16.39600  1.000 36.95903  ? 167 ASP L OD1  1 
ATOM   5823 O OD2  . ASP B 2 173 ? 57.22100 5.73600   17.53000  1.000 34.30917  ? 167 ASP L OD2  1 
ATOM   5824 H H    . ASP B 2 173 ? 52.99700 5.79400   15.63300  1.000 26.96108  ? 167 ASP L H    1 
ATOM   5825 H HA   . ASP B 2 173 ? 54.19500 3.80600   16.83000  1.000 29.82999  ? 167 ASP L HA   1 
ATOM   5826 H HB2  . ASP B 2 173 ? 55.29100 5.11900   15.22400  1.000 32.72386  ? 167 ASP L HB2  1 
ATOM   5827 H HB3  . ASP B 2 173 ? 55.25700 6.35700   16.22000  1.000 32.72386  ? 167 ASP L HB3  1 
ATOM   5828 N N    . SER B 2 174 ? 54.58000 4.23200   19.20700  1.000 31.38699  ? 168 SER L N    1 
ATOM   5829 C CA   . SER B 2 174 ? 54.55600 4.46100   20.64700  1.000 34.49938  ? 168 SER L CA   1 
ATOM   5830 C C    . SER B 2 174 ? 55.52500 5.54700   21.09900  1.000 33.91921  ? 168 SER L C    1 
ATOM   5831 O O    . SER B 2 174 ? 55.41700 6.00700   22.24200  1.000 30.63759  ? 168 SER L O    1 
ATOM   5832 C CB   . SER B 2 174 ? 54.87900 3.16300   21.39000  1.000 33.65840  ? 168 SER L CB   1 
ATOM   5833 O OG   . SER B 2 174 ? 56.21600 2.76100   21.14200  1.000 42.71956  ? 168 SER L OG   1 
ATOM   5834 H H    . SER B 2 174 ? 54.89300 3.46500   18.97400  1.000 37.66796  ? 168 SER L H    1 
ATOM   5835 H HA   . SER B 2 174 ? 53.66000 4.74100   20.89100  1.000 41.40283  ? 168 SER L HA   1 
ATOM   5836 H HB2  . SER B 2 174 ? 54.76400 3.30700   22.34200  1.000 40.39365  ? 168 SER L HB2  1 
ATOM   5837 H HB3  . SER B 2 174 ? 54.27800 2.46600   21.08400  1.000 40.39365  ? 168 SER L HB3  1 
ATOM   5838 H HG   . SER B 2 174 ? 56.31700 2.58700   20.32700  1.000 51.26704  ? 168 SER L HG   1 
ATOM   5839 N N    . LYS B 2 175 ? 56.45600 5.97000   20.24600  1.000 34.27952  ? 169 LYS L N    1 
ATOM   5840 C CA   . LYS B 2 175 ? 57.47800 6.93100   20.64300  1.000 31.65762  ? 169 LYS L CA   1 
ATOM   5841 C C    . LYS B 2 175 ? 57.21900 8.32900   20.09500  1.000 31.64889  ? 169 LYS L C    1 
ATOM   5842 O O    . LYS B 2 175 ? 57.21800 9.29600   20.86100  1.000 32.11900  ? 169 LYS L O    1 
ATOM   5843 C CB   . LYS B 2 175 ? 58.85900 6.43800   20.19800  1.000 39.04879  ? 169 LYS L CB   1 
ATOM   5844 C CG   . LYS B 2 175 ? 60.01600 7.26600   20.73000  1.000 42.34840  ? 169 LYS L CG   1 
ATOM   5845 C CD   . LYS B 2 175 ? 61.34000 6.53300   20.55600  1.000 58.86843  ? 169 LYS L CD   1 
ATOM   5846 C CE   . LYS B 2 175 ? 62.51000 7.34000   21.10600  1.000 73.81792  ? 169 LYS L CE   1 
ATOM   5847 N NZ   . LYS B 2 175 ? 62.73300 8.61000   20.35800  1.000 66.94843  ? 169 LYS L NZ   1 
ATOM   5848 H H    . LYS B 2 175 ? 56.51600 5.71100   19.42800  1.000 41.13900  ? 169 LYS L H    1 
ATOM   5849 H HA   . LYS B 2 175 ? 57.48100 6.99700   21.61100  1.000 37.99271  ? 169 LYS L HA   1 
ATOM   5850 H HB2  . LYS B 2 175 ? 58.98000 5.52800   20.51200  1.000 46.86212  ? 169 LYS L HB2  1 
ATOM   5851 H HB3  . LYS B 2 175 ? 58.90000 6.46200   19.22900  1.000 46.86212  ? 169 LYS L HB3  1 
ATOM   5852 H HG2  . LYS B 2 175 ? 60.06400 8.10400   20.24400  1.000 50.82165  ? 169 LYS L HG2  1 
ATOM   5853 H HG3  . LYS B 2 175 ? 59.88300 7.43700   21.67500  1.000 50.82165  ? 169 LYS L HG3  1 
ATOM   5854 H HD2  . LYS B 2 175 ? 61.30400 5.68800   21.03200  1.000 70.64568  ? 169 LYS L HD2  1 
ATOM   5855 H HD3  . LYS B 2 175 ? 61.49700 6.37600   19.61200  1.000 70.64568  ? 169 LYS L HD3  1 
ATOM   5856 H HE2  . LYS B 2 175 ? 62.33200 7.56400   22.03300  1.000 88.58508  ? 169 LYS L HE2  1 
ATOM   5857 H HE3  . LYS B 2 175 ? 63.31900 6.80800   21.04300  1.000 88.58508  ? 169 LYS L HE3  1 
ATOM   5858 H HZ1  . LYS B 2 175 ? 63.46200 9.02000   20.66400  1.000 80.34168  ? 169 LYS L HZ1  1 
ATOM   5859 H HZ2  . LYS B 2 175 ? 62.84100 8.43900   19.49100  1.000 80.34168  ? 169 LYS L HZ2  1 
ATOM   5860 H HZ3  . LYS B 2 175 ? 62.03300 9.15100   20.46100  1.000 80.34168  ? 169 LYS L HZ3  1 
ATOM   5861 N N    . ASP B 2 176 ? 56.99200 8.46300   18.78800  1.000 30.64880  ? 170 ASP L N    1 
ATOM   5862 C CA   . ASP B 2 176 ? 56.76000 9.76500   18.17800  1.000 28.16798  ? 170 ASP L CA   1 
ATOM   5863 C C    . ASP B 2 176 ? 55.32200 9.97300   17.71900  1.000 26.60774  ? 170 ASP L C    1 
ATOM   5864 O O    . ASP B 2 176 ? 55.01000 11.03800  17.17500  1.000 26.04808  ? 170 ASP L O    1 
ATOM   5865 C CB   . ASP B 2 176 ? 57.70400 9.96900   16.98700  1.000 30.75835  ? 170 ASP L CB   1 
ATOM   5866 C CG   . ASP B 2 176 ? 57.61500 8.84500   15.97700  1.000 34.29955  ? 170 ASP L CG   1 
ATOM   5867 O OD1  . ASP B 2 176 ? 56.48300 8.41600   15.66300  1.000 31.66973  ? 170 ASP L OD1  1 
ATOM   5868 O OD2  . ASP B 2 176 ? 58.67600 8.39200   15.49700  1.000 36.71916  ? 170 ASP L OD2  1 
ATOM   5869 H H    . ASP B 2 176 ? 56.96900 7.80700   18.23200  1.000 36.78213  ? 170 ASP L H    1 
ATOM   5870 H HA   . ASP B 2 176 ? 56.95700 10.44400  18.84100  1.000 33.80514  ? 170 ASP L HA   1 
ATOM   5871 H HB2  . ASP B 2 176 ? 57.47300 10.79700  16.53700  1.000 36.91360  ? 170 ASP L HB2  1 
ATOM   5872 H HB3  . ASP B 2 176 ? 58.61800 10.01200  17.31000  1.000 36.91360  ? 170 ASP L HB3  1 
ATOM   5873 N N    . SER B 2 177 ? 54.44500 8.98700   17.90500  1.000 24.82684  ? 171 SER L N    1 
ATOM   5874 C CA   . SER B 2 177 ? 53.02100 9.10600   17.61000  1.000 22.90617  ? 171 SER L CA   1 
ATOM   5875 C C    . SER B 2 177 ? 52.73000 9.28300   16.12400  1.000 23.70691  ? 171 SER L C    1 
ATOM   5876 O O    . SER B 2 177 ? 51.63000 9.71200   15.75700  1.000 23.55679  ? 171 SER L O    1 
ATOM   5877 C CB   . SER B 2 177 ? 52.39400 10.26400  18.39700  1.000 27.38938  ? 171 SER L CB   1 
ATOM   5878 O OG   . SER B 2 177 ? 52.65500 10.12800  19.78300  1.000 23.69646  ? 171 SER L OG   1 
ATOM   5879 H H    . SER B 2 177 ? 54.66200 8.21400   18.21300  1.000 29.79578  ? 171 SER L H    1 
ATOM   5880 H HA   . SER B 2 177 ? 52.59500 8.27800   17.88300  1.000 27.49098  ? 171 SER L HA   1 
ATOM   5881 H HB2  . SER B 2 177 ? 52.77400 11.10100  18.08500  1.000 32.87083  ? 171 SER L HB2  1 
ATOM   5882 H HB3  . SER B 2 177 ? 51.43500 10.26100  18.25400  1.000 32.87083  ? 171 SER L HB3  1 
ATOM   5883 H HG   . SER B 2 177 ? 52.40100 9.37400   20.05000  1.000 28.43932  ? 171 SER L HG   1 
ATOM   5884 N N    . THR B 2 178 ? 53.68000 8.96100   15.25300  1.000 22.01593  ? 172 THR L N    1 
ATOM   5885 C CA   . THR B 2 178 ? 53.44300 9.07000   13.82400  1.000 23.29816  ? 172 THR L CA   1 
ATOM   5886 C C    . THR B 2 178 ? 52.87300 7.77000   13.25500  1.000 23.14821  ? 172 THR L C    1 
ATOM   5887 O O    . THR B 2 178 ? 52.85500 6.72000   13.90400  1.000 20.22474  ? 172 THR L O    1 
ATOM   5888 C CB   . THR B 2 178 ? 54.73200 9.42500   13.07700  1.000 22.93774  ? 172 THR L CB   1 
ATOM   5889 O OG1  . THR B 2 178 ? 55.70600 8.39200   13.28600  1.000 23.37752  ? 172 THR L OG1  1 
ATOM   5890 C CG2  . THR B 2 178 ? 55.28300 10.75800  13.55500  1.000 24.23847  ? 172 THR L CG2  1 
ATOM   5891 H H    . THR B 2 178 ? 54.46400 8.67900   15.46700  1.000 26.42269  ? 172 THR L H    1 
ATOM   5892 H HA   . THR B 2 178 ? 52.79700 9.78100   13.68600  1.000 27.96136  ? 172 THR L HA   1 
ATOM   5893 H HB   . THR B 2 178 ? 54.54600 9.50200   12.12900  1.000 27.52886  ? 172 THR L HB   1 
ATOM   5894 H HG1  . THR B 2 178 ? 55.90200 8.34300   14.10100  1.000 28.05659  ? 172 THR L HG1  1 
ATOM   5895 H HG21 . THR B 2 178 ? 56.08900 10.97900  13.06300  1.000 29.08973  ? 172 THR L HG21 1 
ATOM   5896 H HG22 . THR B 2 178 ? 54.62600 11.45800  13.41300  1.000 29.08973  ? 172 THR L HG22 1 
ATOM   5897 H HG23 . THR B 2 178 ? 55.49300 10.71000  14.50000  1.000 29.08973  ? 172 THR L HG23 1 
ATOM   5898 N N    . TYR B 2 179 ? 52.40000 7.86500   12.01500  1.000 22.85837  ? 173 TYR L N    1 
ATOM   5899 C CA   . TYR B 2 179 ? 51.98300 6.72700   11.21700  1.000 22.87829  ? 173 TYR L CA   1 
ATOM   5900 C C    . TYR B 2 179 ? 52.97800 6.49400   10.08600  1.000 23.03937  ? 173 TYR L C    1 
ATOM   5901 O O    . TYR B 2 179 ? 53.75400 7.37900   9.71200   1.000 18.12584  ? 173 TYR L O    1 
ATOM   5902 C CB   . TYR B 2 179 ? 50.59800 6.94200   10.60000  1.000 23.75799  ? 173 TYR L CB   1 
ATOM   5903 C CG   . TYR B 2 179 ? 49.50900 7.33600   11.55900  1.000 28.48863  ? 173 TYR L CG   1 
ATOM   5904 C CD1  . TYR B 2 179 ? 49.27300 8.67000   11.85600  1.000 30.54898  ? 173 TYR L CD1  1 
ATOM   5905 C CD2  . TYR B 2 179 ? 48.69700 6.37800   12.14700  1.000 26.86649  ? 173 TYR L CD2  1 
ATOM   5906 C CE1  . TYR B 2 179 ? 48.27000 9.04000   12.72100  1.000 28.77648  ? 173 TYR L CE1  1 
ATOM   5907 C CE2  . TYR B 2 179 ? 47.68700 6.73800   13.01400  1.000 31.20833  ? 173 TYR L CE2  1 
ATOM   5908 C CZ   . TYR B 2 179 ? 47.47800 8.07300   13.29700  1.000 34.39916  ? 173 TYR L CZ   1 
ATOM   5909 O OH   . TYR B 2 179 ? 46.47600 8.44900   14.16300  1.000 39.41959  ? 173 TYR L OH   1 
ATOM   5910 H H    . TYR B 2 179 ? 52.30800 8.61300   11.60100  1.000 27.43361  ? 173 TYR L H    1 
ATOM   5911 H HA   . TYR B 2 179 ? 51.95000 5.94600   11.79200  1.000 27.45752  ? 173 TYR L HA   1 
ATOM   5912 H HB2  . TYR B 2 179 ? 50.66600 7.64800   9.93800   1.000 28.51316  ? 173 TYR L HB2  1 
ATOM   5913 H HB3  . TYR B 2 179 ? 50.32200 6.11500   10.17600  1.000 28.51316  ? 173 TYR L HB3  1 
ATOM   5914 H HD1  . TYR B 2 179 ? 49.80300 9.32600   11.46300  1.000 36.66234  ? 173 TYR L HD1  1 
ATOM   5915 H HD2  . TYR B 2 179 ? 48.83500 5.47900   11.95400  1.000 32.24336  ? 173 TYR L HD2  1 
ATOM   5916 H HE1  . TYR B 2 179 ? 48.12800 9.93900   12.91600  1.000 34.53535  ? 173 TYR L HE1  1 
ATOM   5917 H HE2  . TYR B 2 179 ? 47.15100 6.08700   13.40400  1.000 37.45357  ? 173 TYR L HE2  1 
ATOM   5918 H HH   . TYR B 2 179 ? 46.05200 7.77200   14.42300  1.000 47.30708  ? 173 TYR L HH   1 
ATOM   5919 N N    . SER B 2 180 ? 52.92700 5.29000   9.52900   1.000 20.30768  ? 174 SER L N    1 
ATOM   5920 C CA   . SER B 2 180 ? 53.59500 4.96400   8.27900   1.000 20.08811  ? 174 SER L CA   1 
ATOM   5921 C C    . SER B 2 180 ? 52.60800 4.20500   7.40600   1.000 17.75684  ? 174 SER L C    1 
ATOM   5922 O O    . SER B 2 180 ? 51.67300 3.57200   7.90500   1.000 16.09569  ? 174 SER L O    1 
ATOM   5923 C CB   . SER B 2 180 ? 54.86500 4.14800   8.51500   1.000 23.87037  ? 174 SER L CB   1 
ATOM   5924 O OG   . SER B 2 180 ? 55.84600 4.93700   9.16700   1.000 21.98802  ? 174 SER L OG   1 
ATOM   5925 H H    . SER B 2 180 ? 52.49800 4.62600   9.86800   1.000 24.37279  ? 174 SER L H    1 
ATOM   5926 H HA   . SER B 2 180 ? 53.86600 5.76900   7.81000   1.000 24.10931  ? 174 SER L HA   1 
ATOM   5927 H HB2  . SER B 2 180 ? 54.65100 3.38200   9.07100   1.000 28.64802  ? 174 SER L HB2  1 
ATOM   5928 H HB3  . SER B 2 180 ? 55.21400 3.85000   7.66000   1.000 28.64802  ? 174 SER L HB3  1 
ATOM   5929 H HG   . SER B 2 180 ? 56.61300 4.63900   8.99800   1.000 26.38920  ? 174 SER L HG   1 
ATOM   5930 N N    . LEU B 2 181 ? 52.80700 4.28700   6.09600   1.000 17.69742  ? 175 LEU L N    1 
ATOM   5931 C CA   . LEU B 2 181 ? 51.85200 3.74700   5.14000   1.000 16.96643  ? 175 LEU L CA   1 
ATOM   5932 C C    . LEU B 2 181 ? 52.61000 3.16500   3.96200   1.000 16.62646  ? 175 LEU L C    1 
ATOM   5933 O O    . LEU B 2 181 ? 53.63100 3.71100   3.53800   1.000 16.41780  ? 175 LEU L O    1 
ATOM   5934 C CB   . LEU B 2 181 ? 50.87000 4.84000   4.68500   1.000 18.76801  ? 175 LEU L CB   1 
ATOM   5935 C CG   . LEU B 2 181 ? 49.83600 4.52800   3.60400   1.000 21.77910  ? 175 LEU L CG   1 
ATOM   5936 C CD1  . LEU B 2 181 ? 48.63000 5.44000   3.74800   1.000 25.41016  ? 175 LEU L CD1  1 
ATOM   5937 C CD2  . LEU B 2 181 ? 50.42700 4.69300   2.22100   1.000 20.89885  ? 175 LEU L CD2  1 
ATOM   5938 H H    . LEU B 2 181 ? 53.49500 4.65500   5.73400   1.000 21.24048  ? 175 LEU L H    1 
ATOM   5939 H HA   . LEU B 2 181 ? 51.33500 3.02800   5.53600   1.000 20.36329  ? 175 LEU L HA   1 
ATOM   5940 H HB2  . LEU B 2 181 ? 50.36800 5.11900   5.46600   1.000 22.52518  ? 175 LEU L HB2  1 
ATOM   5941 H HB3  . LEU B 2 181 ? 51.39900 5.58000   4.34800   1.000 22.52518  ? 175 LEU L HB3  1 
ATOM   5942 H HG   . LEU B 2 181 ? 49.55500 3.60500   3.71000   1.000 26.13849  ? 175 LEU L HG   1 
ATOM   5943 H HD11 . LEU B 2 181 ? 47.95600 5.17600   3.10200   1.000 30.49576  ? 175 LEU L HD11 1 
ATOM   5944 H HD12 . LEU B 2 181 ? 48.27700 5.35700   4.64700   1.000 30.49576  ? 175 LEU L HD12 1 
ATOM   5945 H HD13 . LEU B 2 181 ? 48.90500 6.35500   3.58300   1.000 30.49576  ? 175 LEU L HD13 1 
ATOM   5946 H HD21 . LEU B 2 181 ? 49.71800 4.61800   1.56400   1.000 25.08219  ? 175 LEU L HD21 1 
ATOM   5947 H HD22 . LEU B 2 181 ? 50.84600 5.56500   2.15800   1.000 25.08219  ? 175 LEU L HD22 1 
ATOM   5948 H HD23 . LEU B 2 181 ? 51.08800 3.99700   2.07500   1.000 25.08219  ? 175 LEU L HD23 1 
ATOM   5949 N N    . SER B 2 182 ? 52.11700 2.04100   3.45400   1.000 15.88634  ? 176 SER L N    1 
ATOM   5950 C CA   . SER B 2 182 ? 52.62100 1.43300   2.23400   1.000 16.10673  ? 176 SER L CA   1 
ATOM   5951 C C    . SER B 2 182 ? 51.50000 1.42300   1.20800   1.000 18.15753  ? 176 SER L C    1 
ATOM   5952 O O    . SER B 2 182 ? 50.34600 1.14100   1.54500   1.000 20.56915  ? 176 SER L O    1 
ATOM   5953 C CB   . SER B 2 182 ? 53.10300 0.00200   2.47100   1.000 18.71847  ? 176 SER L CB   1 
ATOM   5954 O OG   . SER B 2 182 ? 52.00800 -0.82800  2.82500   1.000 19.45922  ? 176 SER L OG   1 
ATOM   5955 H H    . SER B 2 182 ? 51.47100 1.60100   3.81200   1.000 19.06718  ? 176 SER L H    1 
ATOM   5956 H HA   . SER B 2 182 ? 53.37200 1.94600   1.89600   1.000 19.33165  ? 176 SER L HA   1 
ATOM   5957 H HB2  . SER B 2 182 ? 53.51000 -0.33600  1.65900   1.000 22.46573  ? 176 SER L HB2  1 
ATOM   5958 H HB3  . SER B 2 182 ? 53.75100 -0.00000  3.19300   1.000 22.46573  ? 176 SER L HB3  1 
ATOM   5959 H HG   . SER B 2 182 ? 52.27100 -1.61800  2.93900   1.000 23.35463  ? 176 SER L HG   1 
ATOM   5960 N N    . SER B 2 183 ? 51.83500 1.74600   -0.03300  1.000 18.56930  ? 177 SER L N    1 
ATOM   5961 C CA   . SER B 2 183 ? 50.93800 1.54800   -1.16000  1.000 18.20682  ? 177 SER L CA   1 
ATOM   5962 C C    . SER B 2 183 ? 51.64900 0.65000   -2.15700  1.000 17.43716  ? 177 SER L C    1 
ATOM   5963 O O    . SER B 2 183 ? 52.78700 0.93200   -2.54800  1.000 16.51847  ? 177 SER L O    1 
ATOM   5964 C CB   . SER B 2 183 ? 50.54300 2.86800   -1.81500  1.000 20.08892  ? 177 SER L CB   1 
ATOM   5965 O OG   . SER B 2 183 ? 49.69600 2.63600   -2.92800  1.000 21.20970  ? 177 SER L OG   1 
ATOM   5966 H H    . SER B 2 183 ? 52.59300 2.08800   -0.25100  1.000 22.28673  ? 177 SER L H    1 
ATOM   5967 H HA   . SER B 2 183 ? 50.11800 1.12300   -0.86500  1.000 21.85175  ? 177 SER L HA   1 
ATOM   5968 H HB2  . SER B 2 183 ? 50.07300 3.41600   -1.16700  1.000 24.11027  ? 177 SER L HB2  1 
ATOM   5969 H HB3  . SER B 2 183 ? 51.34400 3.32500   -2.11500  1.000 24.11027  ? 177 SER L HB3  1 
ATOM   5970 H HG   . SER B 2 183 ? 49.43000 3.36800   -3.24500  1.000 25.45521  ? 177 SER L HG   1 
ATOM   5971 N N    . THR B 2 184 ? 50.98600 -0.43200  -2.55000  1.000 17.78804  ? 178 THR L N    1 
ATOM   5972 C CA   . THR B 2 184 ? 51.55500 -1.41700  -3.45800  1.000 16.02677  ? 178 THR L CA   1 
ATOM   5973 C C    . THR B 2 184 ? 50.75100 -1.41700  -4.74800  1.000 16.55708  ? 178 THR L C    1 
ATOM   5974 O O    . THR B 2 184 ? 49.53700 -1.64600  -4.72800  1.000 16.09624  ? 178 THR L O    1 
ATOM   5975 C CB   . THR B 2 184 ? 51.55900 -2.81000  -2.82800  1.000 19.31883  ? 178 THR L CB   1 
ATOM   5976 O OG1  . THR B 2 184 ? 52.18600 -2.75100  -1.54200  1.000 19.97987  ? 178 THR L OG1  1 
ATOM   5977 C CG2  . THR B 2 184 ? 52.31500 -3.78000  -3.71000  1.000 17.14790  ? 178 THR L CG2  1 
ATOM   5978 H H    . THR B 2 184 ? 50.18600 -0.62100  -2.29700  1.000 21.34922  ? 178 THR L H    1 
ATOM   5979 H HA   . THR B 2 184 ? 52.47000 -1.17200  -3.66700  1.000 19.23570  ? 178 THR L HA   1 
ATOM   5980 H HB   . THR B 2 184 ? 50.64800 -3.12700  -2.72800  1.000 23.18616  ? 178 THR L HB   1 
ATOM   5981 H HG1  . THR B 2 184 ? 51.71200 -2.30500  -1.01100  1.000 23.97942  ? 178 THR L HG1  1 
ATOM   5982 H HG21 . THR B 2 184 ? 52.35900 -4.65000  -3.28300  1.000 20.58104  ? 178 THR L HG21 1 
ATOM   5983 H HG22 . THR B 2 184 ? 51.86500 -3.87100  -4.56400  1.000 20.58104  ? 178 THR L HG22 1 
ATOM   5984 H HG23 . THR B 2 184 ? 53.21700 -3.45700  -3.86100  1.000 20.58104  ? 178 THR L HG23 1 
ATOM   5985 N N    . LEU B 2 185 ? 51.43200 -1.14400  -5.85600  1.000 17.55894  ? 179 LEU L N    1 
ATOM   5986 C CA   . LEU B 2 185 ? 50.86200 -1.20700  -7.19300  1.000 17.90820  ? 179 LEU L CA   1 
ATOM   5987 C C    . LEU B 2 185 ? 51.21900 -2.55700  -7.79100  1.000 17.65808  ? 179 LEU L C    1 
ATOM   5988 O O    . LEU B 2 185 ? 52.40300 -2.90200  -7.87500  1.000 15.98766  ? 179 LEU L O    1 
ATOM   5989 C CB   . LEU B 2 185 ? 51.41000 -0.08600  -8.07200  1.000 15.51592  ? 179 LEU L CB   1 
ATOM   5990 C CG   . LEU B 2 185 ? 50.98900 -0.05100  -9.54300  1.000 19.14923  ? 179 LEU L CG   1 
ATOM   5991 C CD1  . LEU B 2 185 ? 49.55600 0.43200   -9.66100  1.000 20.44880  ? 179 LEU L CD1  1 
ATOM   5992 C CD2  . LEU B 2 185 ? 51.92500 0.82900   -10.36700 1.000 17.29725  ? 179 LEU L CD2  1 
ATOM   5993 H H    . LEU B 2 185 ? 52.26000 -0.91000  -5.85700  1.000 21.07430  ? 179 LEU L H    1 
ATOM   5994 H HA   . LEU B 2 185 ? 49.89700 -1.11600  -7.14700  1.000 21.49341  ? 179 LEU L HA   1 
ATOM   5995 H HB2  . LEU B 2 185 ? 51.12900 0.75700   -7.68300  1.000 18.62268  ? 179 LEU L HB2  1 
ATOM   5996 H HB3  . LEU B 2 185 ? 52.37800 -0.15000  -8.06200  1.000 18.62268  ? 179 LEU L HB3  1 
ATOM   5997 H HG   . LEU B 2 185 ? 51.04500 -0.94900  -9.90500  1.000 22.98265  ? 179 LEU L HG   1 
ATOM   5998 H HD11 . LEU B 2 185 ? 49.30400 0.44700   -10.59800 1.000 24.54213  ? 179 LEU L HD11 1 
ATOM   5999 H HD12 . LEU B 2 185 ? 48.97700 -0.17400  -9.17300  1.000 24.54213  ? 179 LEU L HD12 1 
ATOM   6000 H HD13 . LEU B 2 185 ? 49.49100 1.32500   -9.28700  1.000 24.54213  ? 179 LEU L HD13 1 
ATOM   6001 H HD21 . LEU B 2 185 ? 51.59500 0.87500   -11.27800 1.000 20.76027  ? 179 LEU L HD21 1 
ATOM   6002 H HD22 . LEU B 2 185 ? 51.94700 1.71800   -9.97800  1.000 20.76027  ? 179 LEU L HD22 1 
ATOM   6003 H HD23 . LEU B 2 185 ? 52.81400 0.44200   -10.35600 1.000 20.76027  ? 179 LEU L HD23 1 
ATOM   6004 N N    . THR B 2 186 ? 50.21100 -3.31000  -8.21400  1.000 20.17865  ? 180 THR L N    1 
ATOM   6005 C CA   . THR B 2 186 ? 50.40700 -4.64200  -8.76600  1.000 20.30887  ? 180 THR L CA   1 
ATOM   6006 C C    . THR B 2 186 ? 50.12300 -4.61500  -10.26100 1.000 20.18776  ? 180 THR L C    1 
ATOM   6007 O O    . THR B 2 186 ? 49.01400 -4.26700  -10.67800 1.000 17.38532  ? 180 THR L O    1 
ATOM   6008 C CB   . THR B 2 186 ? 49.50700 -5.66000  -8.07000  1.000 20.12728  ? 180 THR L CB   1 
ATOM   6009 O OG1  . THR B 2 186 ? 49.73700 -5.60700  -6.65900  1.000 22.76961  ? 180 THR L OG1  1 
ATOM   6010 C CG2  . THR B 2 186 ? 49.80100 -7.06800  -8.56900  1.000 23.24961  ? 180 THR L CG2  1 
ATOM   6011 H H    . THR B 2 186 ? 49.38700 -3.06400  -8.19000  1.000 24.21795  ? 180 THR L H    1 
ATOM   6012 H HA   . THR B 2 186 ? 51.33200 -4.90600  -8.63800  1.000 24.37421  ? 180 THR L HA   1 
ATOM   6013 H HB   . THR B 2 186 ? 48.57800 -5.45600  -8.26200  1.000 24.15631  ? 180 THR L HB   1 
ATOM   6014 H HG1  . THR B 2 186 ? 49.46700 -4.87300  -6.35100  1.000 27.32710  ? 180 THR L HG1  1 
ATOM   6015 H HG21 . THR B 2 186 ? 49.24800 -7.71000  -8.09600  1.000 27.90311  ? 180 THR L HG21 1 
ATOM   6016 H HG22 . THR B 2 186 ? 49.61400 -7.13000  -9.51800  1.000 27.90311  ? 180 THR L HG22 1 
ATOM   6017 H HG23 . THR B 2 186 ? 50.73400 -7.28600  -8.41700  1.000 27.90311  ? 180 THR L HG23 1 
ATOM   6018 N N    . LEU B 2 187 ? 51.12700 -4.98500  -11.05300 1.000 22.06805  ? 181 LEU L N    1 
ATOM   6019 C CA   . LEU B 2 187 ? 51.01100 -5.10800  -12.49700 1.000 22.21812  ? 181 LEU L CA   1 
ATOM   6020 C C    . LEU B 2 187 ? 51.51100 -6.48400  -12.91900 1.000 21.05684  ? 181 LEU L C    1 
ATOM   6021 O O    . LEU B 2 187 ? 52.29500 -7.12100  -12.21300 1.000 20.77651  ? 181 LEU L O    1 
ATOM   6022 C CB   . LEU B 2 187 ? 51.83200 -4.03700  -13.22700 1.000 24.13879  ? 181 LEU L CB   1 
ATOM   6023 C CG   . LEU B 2 187 ? 51.71100 -2.58300  -12.77200 1.000 26.68993  ? 181 LEU L CG   1 
ATOM   6024 C CD1  . LEU B 2 187 ? 52.71500 -1.72100  -13.53000 1.000 24.73990  ? 181 LEU L CD1  1 
ATOM   6025 C CD2  . LEU B 2 187 ? 50.30000 -2.06800  -12.97200 1.000 24.47823  ? 181 LEU L CD2  1 
ATOM   6026 H H    . LEU B 2 187 ? 51.91400 -5.17800  -10.76300 1.000 26.48523  ? 181 LEU L H    1 
ATOM   6027 H HA   . LEU B 2 187 ? 50.08000 -5.01100  -12.75000 1.000 26.66531  ? 181 LEU L HA   1 
ATOM   6028 H HB2  . LEU B 2 187 ? 52.76700 -4.27700  -13.14000 1.000 28.97012  ? 181 LEU L HB2  1 
ATOM   6029 H HB3  . LEU B 2 187 ? 51.57000 -4.05600  -14.16100 1.000 28.97012  ? 181 LEU L HB3  1 
ATOM   6030 H HG   . LEU B 2 187 ? 51.90800 -2.52600  -11.82300 1.000 32.03148  ? 181 LEU L HG   1 
ATOM   6031 H HD11 . LEU B 2 187 ? 52.60200 -0.79500  -13.26300 1.000 29.69146  ? 181 LEU L HD11 1 
ATOM   6032 H HD12 . LEU B 2 187 ? 53.61300 -2.01900  -13.31600 1.000 29.69146  ? 181 LEU L HD12 1 
ATOM   6033 H HD13 . LEU B 2 187 ? 52.55400 -1.81300  -14.48200 1.000 29.69146  ? 181 LEU L HD13 1 
ATOM   6034 H HD21 . LEU B 2 187 ? 50.26000 -1.13900  -12.69700 1.000 29.37744  ? 181 LEU L HD21 1 
ATOM   6035 H HD22 . LEU B 2 187 ? 50.06600 -2.14500  -13.91100 1.000 29.37744  ? 181 LEU L HD22 1 
ATOM   6036 H HD23 . LEU B 2 187 ? 49.69100 -2.59900  -12.43500 1.000 29.37744  ? 181 LEU L HD23 1 
ATOM   6037 N N    . SER B 2 188 ? 51.06700 -6.93900  -14.08700 1.000 24.81853  ? 182 SER L N    1 
ATOM   6038 C CA   . SER B 2 188 ? 51.69600 -8.10500  -14.68700 1.000 24.49810  ? 182 SER L CA   1 
ATOM   6039 C C    . SER B 2 188 ? 53.11300 -7.74100  -15.11300 1.000 22.62599  ? 182 SER L C    1 
ATOM   6040 O O    . SER B 2 188 ? 53.42700 -6.57300  -15.35500 1.000 22.74620  ? 182 SER L O    1 
ATOM   6041 C CB   . SER B 2 188 ? 50.90000 -8.59400  -15.89400 1.000 27.39857  ? 182 SER L CB   1 
ATOM   6042 O OG   . SER B 2 188 ? 50.92700 -7.63300  -16.93500 1.000 26.05634  ? 182 SER L OG   1 
ATOM   6043 H H    . SER B 2 188 ? 50.42000 -6.59700  -14.53900 1.000 29.78580  ? 182 SER L H    1 
ATOM   6044 H HA   . SER B 2 188 ? 51.72600 -8.83200  -14.04600 1.000 29.40129  ? 182 SER L HA   1 
ATOM   6045 H HB2  . SER B 2 188 ? 51.29100 -9.42100  -16.21700 1.000 32.88186  ? 182 SER L HB2  1 
ATOM   6046 H HB3  . SER B 2 188 ? 49.98000 -8.74500  -15.62700 1.000 32.88186  ? 182 SER L HB3  1 
ATOM   6047 H HG   . SER B 2 188 ? 50.46100 -7.89700  -17.58200 1.000 31.27117  ? 182 SER L HG   1 
ATOM   6048 N N    . LYS B 2 189 ? 53.98200 -8.75200  -15.19400 1.000 22.65695  ? 183 LYS L N    1 
ATOM   6049 C CA   . LYS B 2 189 ? 55.32500 -8.50200  -15.70900 1.000 24.67818  ? 183 LYS L CA   1 
ATOM   6050 C C    . LYS B 2 189 ? 55.24800 -7.86300  -17.08700 1.000 24.60782  ? 183 LYS L C    1 
ATOM   6051 O O    . LYS B 2 189 ? 55.93600 -6.87500  -17.37200 1.000 22.24596  ? 183 LYS L O    1 
ATOM   6052 C CB   . LYS B 2 189 ? 56.13500 -9.79700  -15.78200 1.000 27.89931  ? 183 LYS L CB   1 
ATOM   6053 C CG   . LYS B 2 189 ? 57.46000 -9.62200  -16.53000 1.000 25.50738  ? 183 LYS L CG   1 
ATOM   6054 C CD   . LYS B 2 189 ? 58.21300 -10.92500 -16.72300 1.000 30.18957  ? 183 LYS L CD   1 
ATOM   6055 C CE   . LYS B 2 189 ? 59.51300 -10.67400 -17.47400 1.000 37.22810  ? 183 LYS L CE   1 
ATOM   6056 N NZ   . LYS B 2 189 ? 60.39800 -11.86800 -17.49300 1.000 43.56819  ? 183 LYS L NZ   1 
ATOM   6057 H H    . LYS B 2 189 ? 53.82300 -9.56500  -14.96300 1.000 27.19192  ? 183 LYS L H    1 
ATOM   6058 H HA   . LYS B 2 189 ? 55.78100 -7.90300  -15.09800 1.000 29.61738  ? 183 LYS L HA   1 
ATOM   6059 H HB2  . LYS B 2 189 ? 56.33600 -10.09500 -14.88000 1.000 33.48274  ? 183 LYS L HB2  1 
ATOM   6060 H HB3  . LYS B 2 189 ? 55.61400 -10.47000 -16.24600 1.000 33.48274  ? 183 LYS L HB3  1 
ATOM   6061 H HG2  . LYS B 2 189 ? 57.27900 -9.25000  -17.40700 1.000 30.61243  ? 183 LYS L HG2  1 
ATOM   6062 H HG3  . LYS B 2 189 ? 58.03000 -9.02100  -16.02500 1.000 30.61243  ? 183 LYS L HG3  1 
ATOM   6063 H HD2  . LYS B 2 189 ? 58.42400 -11.31200 -15.85900 1.000 36.23106  ? 183 LYS L HD2  1 
ATOM   6064 H HD3  . LYS B 2 189 ? 57.67100 -11.54200 -17.23900 1.000 36.23106  ? 183 LYS L HD3  1 
ATOM   6065 H HE2  . LYS B 2 189 ? 59.30800 -10.43700 -18.39200 1.000 44.67729  ? 183 LYS L HE2  1 
ATOM   6066 H HE3  . LYS B 2 189 ? 59.99300 -9.95000  -17.04300 1.000 44.67729  ? 183 LYS L HE3  1 
ATOM   6067 H HZ1  . LYS B 2 189 ? 61.15200 -11.68100 -17.92600 1.000 52.28539  ? 183 LYS L HZ1  1 
ATOM   6068 H HZ2  . LYS B 2 189 ? 60.59500 -12.11400 -16.66100 1.000 52.28539  ? 183 LYS L HZ2  1 
ATOM   6069 H HZ3  . LYS B 2 189 ? 59.98900 -12.54300 -17.90400 1.000 52.28539  ? 183 LYS L HZ3  1 
ATOM   6070 N N    . ALA B 2 190 ? 54.40900 -8.42700  -17.95900 1.000 25.74853  ? 184 ALA L N    1 
ATOM   6071 C CA   . ALA B 2 190 ? 54.26600 -7.92500  -19.31800 1.000 25.98759  ? 184 ALA L CA   1 
ATOM   6072 C C    . ALA B 2 190 ? 53.92500 -6.44300  -19.32300 1.000 27.89836  ? 184 ALA L C    1 
ATOM   6073 O O    . ALA B 2 190 ? 54.53000 -5.65400  -20.05600 1.000 26.77717  ? 184 ALA L O    1 
ATOM   6074 C CB   . ALA B 2 190 ? 53.18800 -8.72600  -20.05000 1.000 30.98946  ? 184 ALA L CB   1 
ATOM   6075 H H    . ALA B 2 190 ? 53.91000 -9.10500  -17.78400 1.000 30.90180  ? 184 ALA L H    1 
ATOM   6076 H HA   . ALA B 2 190 ? 55.10700 -8.04100  -19.78900 1.000 31.18868  ? 184 ALA L HA   1 
ATOM   6077 H HB1  . ALA B 2 190 ? 53.10800 -8.39400  -20.95800 1.000 37.19093  ? 184 ALA L HB1  1 
ATOM   6078 H HB2  . ALA B 2 190 ? 53.44300 -9.66200  -20.06100 1.000 37.19093  ? 184 ALA L HB2  1 
ATOM   6079 H HB3  . ALA B 2 190 ? 52.34400 -8.61900  -19.58400 1.000 37.19093  ? 184 ALA L HB3  1 
ATOM   6080 N N    . ASP B 2 191 ? 52.94800 -6.04600  -18.50500 1.000 30.12911  ? 185 ASP L N    1 
ATOM   6081 C CA   . ASP B 2 191 ? 52.58000 -4.63700  -18.44500 1.000 29.91757  ? 185 ASP L CA   1 
ATOM   6082 C C    . ASP B 2 191 ? 53.71700 -3.79700  -17.87700 1.000 27.98922  ? 185 ASP L C    1 
ATOM   6083 O O    . ASP B 2 191 ? 54.01600 -2.71700  -18.39800 1.000 25.79732  ? 185 ASP L O    1 
ATOM   6084 C CB   . ASP B 2 191 ? 51.30600 -4.46200  -17.61700 1.000 33.89794  ? 185 ASP L CB   1 
ATOM   6085 C CG   . ASP B 2 191 ? 50.07200 -5.03100  -18.31000 1.000 46.54803  ? 185 ASP L CG   1 
ATOM   6086 O OD1  . ASP B 2 191 ? 50.16200 -5.38300  -19.50700 1.000 44.44737  ? 185 ASP L OD1  1 
ATOM   6087 O OD2  . ASP B 2 191 ? 49.01100 -5.12800  -17.65600 1.000 52.10765  ? 185 ASP L OD2  1 
ATOM   6088 H H    . ASP B 2 191 ? 52.49500 -6.56300  -17.98800 1.000 36.15850  ? 185 ASP L H    1 
ATOM   6089 H HA   . ASP B 2 191 ? 52.39400 -4.32100  -19.34300 1.000 35.90466  ? 185 ASP L HA   1 
ATOM   6090 H HB2  . ASP B 2 191 ? 51.41300 -4.92100  -16.77000 1.000 40.68110  ? 185 ASP L HB2  1 
ATOM   6091 H HB3  . ASP B 2 191 ? 51.15500 -3.51600  -17.46500 1.000 40.68110  ? 185 ASP L HB3  1 
ATOM   6092 N N    . TYR B 2 192 ? 54.37400 -4.28100  -16.81900 1.000 24.80749  ? 186 TYR L N    1 
ATOM   6093 C CA   . TYR B 2 192 ? 55.45700 -3.51200  -16.21600 1.000 21.94660  ? 186 TYR L CA   1 
ATOM   6094 C C    . TYR B 2 192 ? 56.56800 -3.23300  -17.21900 1.000 26.00998  ? 186 TYR L C    1 
ATOM   6095 O O    . TYR B 2 192 ? 57.15300 -2.14400  -17.22400 1.000 21.95633  ? 186 TYR L O    1 
ATOM   6096 C CB   . TYR B 2 192 ? 56.02500 -4.25200  -15.00700 1.000 23.84943  ? 186 TYR L CB   1 
ATOM   6097 C CG   . TYR B 2 192 ? 57.23600 -3.57300  -14.41400 1.000 20.96787  ? 186 TYR L CG   1 
ATOM   6098 C CD1  . TYR B 2 192 ? 57.10000 -2.44100  -13.62500 1.000 19.14664  ? 186 TYR L CD1  1 
ATOM   6099 C CD2  . TYR B 2 192 ? 58.51500 -4.06000  -14.64400 1.000 21.08665  ? 186 TYR L CD2  1 
ATOM   6100 C CE1  . TYR B 2 192 ? 58.19600 -1.81600  -13.08200 1.000 19.66847  ? 186 TYR L CE1  1 
ATOM   6101 C CE2  . TYR B 2 192 ? 59.62400 -3.43600  -14.10100 1.000 21.00668  ? 186 TYR L CE2  1 
ATOM   6102 C CZ   . TYR B 2 192 ? 59.45500 -2.31300  -13.31900 1.000 19.90769  ? 186 TYR L CZ   1 
ATOM   6103 O OH   . TYR B 2 192 ? 60.54300 -1.67900  -12.76500 1.000 18.14636  ? 186 TYR L OH   1 
ATOM   6104 H H    . TYR B 2 192 ? 54.21400 -5.03700  -16.44100 1.000 29.77256  ? 186 TYR L H    1 
ATOM   6105 H HA   . TYR B 2 192 ? 55.09500 -2.66400  -15.91300 1.000 26.33949  ? 186 TYR L HA   1 
ATOM   6106 H HB2  . TYR B 2 192 ? 55.34300 -4.30000  -14.31900 1.000 28.62289  ? 186 TYR L HB2  1 
ATOM   6107 H HB3  . TYR B 2 192 ? 56.28600 -5.14500  -15.27900 1.000 28.62289  ? 186 TYR L HB3  1 
ATOM   6108 H HD1  . TYR B 2 192 ? 56.25100 -2.09900  -13.46000 1.000 22.97953  ? 186 TYR L HD1  1 
ATOM   6109 H HD2  . TYR B 2 192 ? 58.62800 -4.81700  -15.17200 1.000 25.30756  ? 186 TYR L HD2  1 
ATOM   6110 H HE1  . TYR B 2 192 ? 58.08600 -1.05800  -12.55500 1.000 23.60574  ? 186 TYR L HE1  1 
ATOM   6111 H HE2  . TYR B 2 192 ? 60.47600 -3.77100  -14.26200 1.000 25.21159  ? 186 TYR L HE2  1 
ATOM   6112 H HH   . TYR B 2 192 ? 60.28900 -1.02800  -12.29800 1.000 21.77920  ? 186 TYR L HH   1 
ATOM   6113 N N    . GLU B 2 193 ? 56.87600 -4.20700  -18.07400 1.000 23.10615  ? 187 GLU L N    1 
ATOM   6114 C CA   . GLU B 2 193 ? 57.95900 -4.05500  -19.03500 1.000 25.96826  ? 187 GLU L CA   1 
ATOM   6115 C C    . GLU B 2 193 ? 57.58700 -3.17400  -20.22000 1.000 24.68687  ? 187 GLU L C    1 
ATOM   6116 O O    . GLU B 2 193 ? 58.47500 -2.80900  -20.99800 1.000 27.66894  ? 187 GLU L O    1 
ATOM   6117 C CB   . GLU B 2 193 ? 58.40500 -5.43100  -19.53400 1.000 27.63907  ? 187 GLU L CB   1 
ATOM   6118 C CG   . GLU B 2 193 ? 59.03300 -6.30300  -18.45900 1.000 29.59870  ? 187 GLU L CG   1 
ATOM   6119 C CD   . GLU B 2 193 ? 60.39400 -5.79800  -18.02100 1.000 35.75895  ? 187 GLU L CD   1 
ATOM   6120 O OE1  . GLU B 2 193 ? 60.93200 -4.88600  -18.68500 1.000 39.15886  ? 187 GLU L OE1  1 
ATOM   6121 O OE2  . GLU B 2 193 ? 60.92700 -6.31200  -17.01400 1.000 38.00933  ? 187 GLU L OE2  1 
ATOM   6122 H H    . GLU B 2 193 ? 56.47100 -4.96500  -18.11600 1.000 27.73095  ? 187 GLU L H    1 
ATOM   6123 H HA   . GLU B 2 193 ? 58.71400 -3.63800  -18.59000 1.000 31.16549  ? 187 GLU L HA   1 
ATOM   6124 H HB2  . GLU B 2 193 ? 57.63100 -5.90200  -19.88200 1.000 33.17046  ? 187 GLU L HB2  1 
ATOM   6125 H HB3  . GLU B 2 193 ? 59.06300 -5.30900  -20.23700 1.000 33.17046  ? 187 GLU L HB3  1 
ATOM   6126 H HG2  . GLU B 2 193 ? 58.45300 -6.31500  -17.68200 1.000 35.52201  ? 187 GLU L HG2  1 
ATOM   6127 H HG3  . GLU B 2 193 ? 59.14300 -7.20300  -18.80400 1.000 35.52201  ? 187 GLU L HG3  1 
ATOM   6128 N N    . LYS B 2 194 ? 56.31200 -2.82200  -20.37400 1.000 24.05625  ? 188 LYS L N    1 
ATOM   6129 C CA   . LYS B 2 194 ? 55.86200 -1.97500  -21.47000 1.000 26.77831  ? 188 LYS L CA   1 
ATOM   6130 C C    . LYS B 2 194 ? 55.97200 -0.48800  -21.16200 1.000 28.38904  ? 188 LYS L C    1 
ATOM   6131 O O    . LYS B 2 194 ? 55.67700 0.33300   -22.03700 1.000 27.34723  ? 188 LYS L O    1 
ATOM   6132 C CB   . LYS B 2 194 ? 54.40500 -2.29200  -21.82700 1.000 27.23684  ? 188 LYS L CB   1 
ATOM   6133 C CG   . LYS B 2 194 ? 54.19700 -3.63100  -22.50900 1.000 34.00830  ? 188 LYS L CG   1 
ATOM   6134 C CD   . LYS B 2 194 ? 52.72300 -3.87500  -22.79800 1.000 37.07787  ? 188 LYS L CD   1 
ATOM   6135 C CE   . LYS B 2 194 ? 52.50500 -5.21400  -23.49500 1.000 43.96835  ? 188 LYS L CE   1 
ATOM   6136 N NZ   . LYS B 2 194 ? 51.11600 -5.34600  -24.02500 1.000 49.00805  ? 188 LYS L NZ   1 
ATOM   6137 H H    . LYS B 2 194 ? 55.67900 -3.06600  -19.84500 1.000 28.87107  ? 188 LYS L H    1 
ATOM   6138 H HA   . LYS B 2 194 ? 56.41700 -2.16900  -22.24100 1.000 32.13755  ? 188 LYS L HA   1 
ATOM   6139 H HB2  . LYS B 2 194 ? 53.88200 -2.29600  -21.01100 1.000 32.68778  ? 188 LYS L HB2  1 
ATOM   6140 H HB3  . LYS B 2 194 ? 54.07900 -1.60400  -22.42800 1.000 32.68778  ? 188 LYS L HB3  1 
ATOM   6141 H HG2  . LYS B 2 194 ? 54.68100 -3.64300  -23.35000 1.000 40.81353  ? 188 LYS L HG2  1 
ATOM   6142 H HG3  . LYS B 2 194 ? 54.51800 -4.34100  -21.93100 1.000 40.81353  ? 188 LYS L HG3  1 
ATOM   6143 H HD2  . LYS B 2 194 ? 52.22800 -3.88100  -21.96400 1.000 44.49701  ? 188 LYS L HD2  1 
ATOM   6144 H HD3  . LYS B 2 194 ? 52.38800 -3.17200  -23.37700 1.000 44.49701  ? 188 LYS L HD3  1 
ATOM   6145 H HE2  . LYS B 2 194 ? 53.12300 -5.29100  -24.23900 1.000 52.76559  ? 188 LYS L HE2  1 
ATOM   6146 H HE3  . LYS B 2 194 ? 52.65800 -5.93200  -22.86100 1.000 52.76559  ? 188 LYS L HE3  1 
ATOM   6147 H HZ1  . LYS B 2 194 ? 51.00800 -6.14400  -24.40300 1.000 58.81323  ? 188 LYS L HZ1  1 
ATOM   6148 H HZ2  . LYS B 2 194 ? 50.52800 -5.25800  -23.36300 1.000 58.81323  ? 188 LYS L HZ2  1 
ATOM   6149 H HZ3  . LYS B 2 194 ? 50.96100 -4.71500  -24.63300 1.000 58.81323  ? 188 LYS L HZ3  1 
ATOM   6150 N N    . HIS B 2 195 ? 56.37400 -0.11800  -19.95200 1.000 26.00836  ? 189 HIS L N    1 
ATOM   6151 C CA   . HIS B 2 195 ? 56.39300 1.27600   -19.54100 1.000 25.15789  ? 189 HIS L CA   1 
ATOM   6152 C C    . HIS B 2 195 ? 57.72500 1.60200   -18.88800 1.000 23.66716  ? 189 HIS L C    1 
ATOM   6153 O O    . HIS B 2 195 ? 58.47400 0.71400   -18.47600 1.000 25.92919  ? 189 HIS L O    1 
ATOM   6154 C CB   . HIS B 2 195 ? 55.23500 1.57300   -18.59100 1.000 25.42854  ? 189 HIS L CB   1 
ATOM   6155 C CG   . HIS B 2 195 ? 53.89600 1.22200   -19.15700 1.000 25.97786  ? 189 HIS L CG   1 
ATOM   6156 N ND1  . HIS B 2 195 ? 53.24300 2.02200   -20.06900 1.000 29.57981  ? 189 HIS L ND1  1 
ATOM   6157 C CD2  . HIS B 2 195 ? 53.08900 0.15500   -18.94700 1.000 29.91005  ? 189 HIS L CD2  1 
ATOM   6158 C CE1  . HIS B 2 195 ? 52.08900 1.46600   -20.39300 1.000 27.47798  ? 189 HIS L CE1  1 
ATOM   6159 N NE2  . HIS B 2 195 ? 51.97200 0.33200   -19.72700 1.000 32.21037  ? 189 HIS L NE2  1 
ATOM   6160 H H    . HIS B 2 195 ? 56.64400 -0.66500  -19.34500 1.000 31.21360  ? 189 HIS L H    1 
ATOM   6161 H HA   . HIS B 2 195 ? 56.30700 1.85200   -20.31700 1.000 30.19303  ? 189 HIS L HA   1 
ATOM   6162 H HB2  . HIS B 2 195 ? 55.35800 1.05900   -17.77700 1.000 30.51781  ? 189 HIS L HB2  1 
ATOM   6163 H HB3  . HIS B 2 195 ? 55.23200 2.52100   -18.38700 1.000 30.51781  ? 189 HIS L HB3  1 
ATOM   6164 H HD1  . HIS B 2 195 ? 53.53900 2.76800   -20.37800 1.000 35.49934  ? 189 HIS L HD1  1 
ATOM   6165 H HD2  . HIS B 2 195 ? 53.26000 -0.56300  -18.38100 1.000 35.89563  ? 189 HIS L HD2  1 
ATOM   6166 H HE1  . HIS B 2 195 ? 51.46600 1.81300   -20.99000 1.000 32.97715  ? 189 HIS L HE1  1 
ATOM   6167 N N    . LYS B 2 196 ? 58.00900 2.89900   -18.79200 1.000 22.89654  ? 190 LYS L N    1 
ATOM   6168 C CA   . LYS B 2 196 ? 59.31500 3.37300   -18.35700 1.000 25.23887  ? 190 LYS L CA   1 
ATOM   6169 C C    . LYS B 2 196 ? 59.29200 4.07200   -17.00800 1.000 22.37687  ? 190 LYS L C    1 
ATOM   6170 O O    . LYS B 2 196 ? 60.09100 3.73700   -16.13000 1.000 22.67769  ? 190 LYS L O    1 
ATOM   6171 C CB   . LYS B 2 196 ? 59.90200 4.32600   -19.41000 1.000 26.19766  ? 190 LYS L CB   1 
ATOM   6172 C CG   . LYS B 2 196 ? 61.36300 4.67900   -19.16400 1.000 30.13842  ? 190 LYS L CG   1 
ATOM   6173 C CD   . LYS B 2 196 ? 62.28800 3.94600   -20.12700 1.000 42.80857  ? 190 LYS L CD   1 
ATOM   6174 C CE   . LYS B 2 196 ? 62.26300 4.58300   -21.51300 1.000 59.12787  ? 190 LYS L CE   1 
ATOM   6175 N NZ   . LYS B 2 196 ? 63.16300 3.88900   -22.48100 1.000 59.74897  ? 190 LYS L NZ   1 
ATOM   6176 H H    . LYS B 2 196 ? 57.45400 3.52900   -18.97700 1.000 27.47942  ? 190 LYS L H    1 
ATOM   6177 H HA   . LYS B 2 196 ? 59.89900 2.60300   -18.27400 1.000 30.29021  ? 190 LYS L HA   1 
ATOM   6178 H HB2  . LYS B 2 196 ? 59.84200 3.90500   -20.28200 1.000 31.44076  ? 190 LYS L HB2  1 
ATOM   6179 H HB3  . LYS B 2 196 ? 59.39200 5.15100   -19.40400 1.000 31.44076  ? 190 LYS L HB3  1 
ATOM   6180 H HG2  . LYS B 2 196 ? 61.48800 5.63300   -19.28900 1.000 36.16968  ? 190 LYS L HG2  1 
ATOM   6181 H HG3  . LYS B 2 196 ? 61.60500 4.42900   -18.25900 1.000 36.16968  ? 190 LYS L HG3  1 
ATOM   6182 H HD2  . LYS B 2 196 ? 63.19700 3.98200   -19.79100 1.000 51.37385  ? 190 LYS L HD2  1 
ATOM   6183 H HD3  . LYS B 2 196 ? 62.00100 3.02300   -20.21000 1.000 51.37385  ? 190 LYS L HD3  1 
ATOM   6184 H HE2  . LYS B 2 196 ? 61.35900 4.54400   -21.86300 1.000 70.95701  ? 190 LYS L HE2  1 
ATOM   6185 H HE3  . LYS B 2 196 ? 62.55200 5.50600   -21.44300 1.000 70.95701  ? 190 LYS L HE3  1 
ATOM   6186 H HZ1  . LYS B 2 196 ? 63.15900 4.31700   -23.26100 1.000 71.70234  ? 190 LYS L HZ1  1 
ATOM   6187 H HZ2  . LYS B 2 196 ? 63.99500 3.87300   -22.16500 1.000 71.70234  ? 190 LYS L HZ2  1 
ATOM   6188 H HZ3  . LYS B 2 196 ? 62.88700 3.05300   -22.60900 1.000 71.70234  ? 190 LYS L HZ3  1 
ATOM   6189 N N    . VAL B 2 197 ? 58.41100 5.04700   -16.81500 1.000 20.67606  ? 191 VAL L N    1 
ATOM   6190 C CA   . VAL B 2 197 ? 58.46200 5.92300   -15.65100 1.000 21.45834  ? 191 VAL L CA   1 
ATOM   6191 C C    . VAL B 2 197 ? 57.36500 5.52400   -14.67700 1.000 19.44735  ? 191 VAL L C    1 
ATOM   6192 O O    . VAL B 2 197 ? 56.17700 5.53600   -15.02300 1.000 19.77799  ? 191 VAL L O    1 
ATOM   6193 C CB   . VAL B 2 197 ? 58.32700 7.39900   -16.05400 1.000 22.47818  ? 191 VAL L CB   1 
ATOM   6194 C CG1  . VAL B 2 197 ? 58.58700 8.29700   -14.85700 1.000 22.37834  ? 191 VAL L CG1  1 
ATOM   6195 C CG2  . VAL B 2 197 ? 59.28200 7.71700   -17.18500 1.000 24.61947  ? 191 VAL L CG2  1 
ATOM   6196 H H    . VAL B 2 197 ? 57.76400 5.22400   -17.35300 1.000 24.81485  ? 191 VAL L H    1 
ATOM   6197 H HA   . VAL B 2 197 ? 59.31500 5.79600   -15.20600 1.000 25.75358  ? 191 VAL L HA   1 
ATOM   6198 H HB   . VAL B 2 197 ? 57.42300 7.56800   -16.36300 1.000 26.97738  ? 191 VAL L HB   1 
ATOM   6199 H HG11 . VAL B 2 197 ? 58.56000 9.22300   -15.14500 1.000 26.85757  ? 191 VAL L HG11 1 
ATOM   6200 H HG12 . VAL B 2 197 ? 57.90300 8.13900   -14.18800 1.000 26.85757  ? 191 VAL L HG12 1 
ATOM   6201 H HG13 . VAL B 2 197 ? 59.46200 8.09000   -14.49100 1.000 26.85757  ? 191 VAL L HG13 1 
ATOM   6202 H HG21 . VAL B 2 197 ? 59.29200 8.67600   -17.33000 1.000 29.54693  ? 191 VAL L HG21 1 
ATOM   6203 H HG22 . VAL B 2 197 ? 60.17000 7.41000   -16.94400 1.000 29.54693  ? 191 VAL L HG22 1 
ATOM   6204 H HG23 . VAL B 2 197 ? 58.98200 7.26400   -17.98800 1.000 29.54693  ? 191 VAL L HG23 1 
ATOM   6205 N N    . TYR B 2 198 ? 57.76400 5.18200   -13.45800 1.000 21.34050  ? 192 TYR L N    1 
ATOM   6206 C CA   . TYR B 2 198 ? 56.84700 4.85700   -12.37500 1.000 16.13594  ? 192 TYR L CA   1 
ATOM   6207 C C    . TYR B 2 198 ? 56.98400 5.91400   -11.29300 1.000 17.00748  ? 192 TYR L C    1 
ATOM   6208 O O    . TYR B 2 198 ? 58.10100 6.30400   -10.93900 1.000 16.94774  ? 192 TYR L O    1 
ATOM   6209 C CB   . TYR B 2 198 ? 57.13800 3.46300   -11.83400 1.000 14.63479  ? 192 TYR L CB   1 
ATOM   6210 C CG   . TYR B 2 198 ? 56.82300 2.41000   -12.86300 1.000 16.00711  ? 192 TYR L CG   1 
ATOM   6211 C CD1  . TYR B 2 198 ? 57.72400 2.10600   -13.87400 1.000 19.97928  ? 192 TYR L CD1  1 
ATOM   6212 C CD2  . TYR B 2 198 ? 55.60300 1.75500   -12.85600 1.000 16.95735  ? 192 TYR L CD2  1 
ATOM   6213 C CE1  . TYR B 2 198 ? 57.42700 1.15400   -14.82900 1.000 18.32710  ? 192 TYR L CE1  1 
ATOM   6214 C CE2  . TYR B 2 198 ? 55.30000 0.80300   -13.80200 1.000 18.13795  ? 192 TYR L CE2  1 
ATOM   6215 C CZ   . TYR B 2 198 ? 56.21000 0.51300   -14.78900 1.000 18.12575  ? 192 TYR L CZ   1 
ATOM   6216 O OH   . TYR B 2 198 ? 55.89700 -0.43600  -15.72900 1.000 23.92100  ? 192 TYR L OH   1 
ATOM   6217 H H    . TYR B 2 198 ? 58.59000 5.13100   -13.22700 1.000 25.61217  ? 192 TYR L H    1 
ATOM   6218 H HA   . TYR B 2 198 ? 55.92800 4.86500   -12.68500 1.000 19.36670  ? 192 TYR L HA   1 
ATOM   6219 H HB2  . TYR B 2 198 ? 58.07800 3.39600   -11.60300 1.000 17.56532  ? 192 TYR L HB2  1 
ATOM   6220 H HB3  . TYR B 2 198 ? 56.59100 3.30000   -11.04900 1.000 17.56532  ? 192 TYR L HB3  1 
ATOM   6221 H HD1  . TYR B 2 198 ? 58.54000 2.55100   -13.90900 1.000 23.97871  ? 192 TYR L HD1  1 
ATOM   6222 H HD2  . TYR B 2 198 ? 54.97700 1.96200   -12.20000 1.000 20.35239  ? 192 TYR L HD2  1 
ATOM   6223 H HE1  . TYR B 2 198 ? 58.04400 0.94800   -15.49400 1.000 21.99609  ? 192 TYR L HE1  1 
ATOM   6224 H HE2  . TYR B 2 198 ? 54.48400 0.35900   -13.77400 1.000 21.76911  ? 192 TYR L HE2  1 
ATOM   6225 H HH   . TYR B 2 198 ? 56.57400 -0.61300  -16.19500 1.000 28.70877  ? 192 TYR L HH   1 
ATOM   6226 N N    . ALA B 2 199 ? 55.85000 6.39400   -10.79400 1.000 17.64695  ? 193 ALA L N    1 
ATOM   6227 C CA   . ALA B 2 199 ? 55.85200 7.50400   -9.85600  1.000 17.65960  ? 193 ALA L CA   1 
ATOM   6228 C C    . ALA B 2 199 ? 54.70300 7.36000   -8.87300  1.000 14.79638  ? 193 ALA L C    1 
ATOM   6229 O O    . ALA B 2 199 ? 53.58700 6.99900   -9.25300  1.000 16.39706  ? 193 ALA L O    1 
ATOM   6230 C CB   . ALA B 2 199 ? 55.73700 8.84900   -10.58700 1.000 16.94679  ? 193 ALA L CB   1 
ATOM   6231 H H    . ALA B 2 199 ? 55.06700 6.09300   -10.98500 1.000 21.17991  ? 193 ALA L H    1 
ATOM   6232 H HA   . ALA B 2 199 ? 56.68000 7.48300   -9.35100  1.000 21.19510  ? 193 ALA L HA   1 
ATOM   6233 H HB1  . ALA B 2 199 ? 55.75300 9.56600   -9.93500  1.000 20.33972  ? 193 ALA L HB1  1 
ATOM   6234 H HB2  . ALA B 2 199 ? 56.48500 8.94100   -11.19800 1.000 20.33972  ? 193 ALA L HB2  1 
ATOM   6235 H HB3  . ALA B 2 199 ? 54.90200 8.86900   -11.08100 1.000 20.33972  ? 193 ALA L HB3  1 
ATOM   6236 N N    . CYS B 2 200 ? 54.98400 7.64000   -7.60700  1.000 15.61744  ? 194 CYS L N    1 
ATOM   6237 C CA   A CYS B 2 200 ? 53.98400 7.68500   -6.54900  0.500 16.11114  ? 194 CYS L CA   1 
ATOM   6238 C CA   B CYS B 2 200 ? 53.94800 7.70100   -6.59000  0.500 16.44287  ? 194 CYS L CA   1 
ATOM   6239 C C    . CYS B 2 200 ? 53.92900 9.10900   -6.01800  1.000 17.97888  ? 194 CYS L C    1 
ATOM   6240 O O    . CYS B 2 200 ? 54.96400 9.64300   -5.60400  1.000 14.12553  ? 194 CYS L O    1 
ATOM   6241 C CB   A CYS B 2 200 ? 54.35200 6.69500   -5.44700  0.500 16.08778  ? 194 CYS L CB   1 
ATOM   6242 C CB   B CYS B 2 200 ? 54.12300 6.65100   -5.48500  0.500 16.20779  ? 194 CYS L CB   1 
ATOM   6243 S SG   A CYS B 2 200 ? 53.58400 6.94300   -3.84900  0.500 17.40948  ? 194 CYS L SG   1 
ATOM   6244 S SG   B CYS B 2 200 ? 55.57300 6.72200   -4.41600  0.500 17.50847  ? 194 CYS L SG   1 
ATOM   6245 H H    A CYS B 2 200 ? 55.77800 7.81400   -7.32600  0.500 18.74450  ? 194 CYS L H    1 
ATOM   6246 H H    B CYS B 2 200 ? 55.77600 7.80000   -7.31200  0.500 18.74450  ? 194 CYS L H    1 
ATOM   6247 H HA   A CYS B 2 200 ? 53.10500 7.45600   -6.88900  0.500 19.33694  ? 194 CYS L HA   1 
ATOM   6248 H HA   B CYS B 2 200 ? 53.08900 7.51100   -6.99800  0.500 19.73501  ? 194 CYS L HA   1 
ATOM   6249 H HB2  A CYS B 2 200 ? 54.10200 5.80700   -5.74700  0.500 19.30890  ? 194 CYS L HB2  1 
ATOM   6250 H HB2  B CYS B 2 200 ? 53.35200 6.71500   -4.90000  0.500 19.45292  ? 194 CYS L HB2  1 
ATOM   6251 H HB3  A CYS B 2 200 ? 55.31100 6.74100   -5.31100  0.500 19.30890  ? 194 CYS L HB3  1 
ATOM   6252 H HB3  B CYS B 2 200 ? 54.14400 5.78000   -5.91300  0.500 19.45292  ? 194 CYS L HB3  1 
ATOM   6253 N N    . GLU B 2 201 ? 52.74600 9.71500   -6.04000  1.000 18.75772  ? 195 GLU L N    1 
ATOM   6254 C CA   . GLU B 2 201 ? 52.53200 11.07900  -5.58200  1.000 16.85539  ? 195 GLU L CA   1 
ATOM   6255 C C    . GLU B 2 201 ? 51.76800 11.06000  -4.26700  1.000 18.46577  ? 195 GLU L C    1 
ATOM   6256 O O    . GLU B 2 201 ? 50.71700 10.41900  -4.15900  1.000 22.32886  ? 195 GLU L O    1 
ATOM   6257 C CB   . GLU B 2 201 ? 51.76000 11.89300  -6.62200  1.000 20.58649  ? 195 GLU L CB   1 
ATOM   6258 C CG   . GLU B 2 201 ? 51.53800 13.34000  -6.21300  1.000 25.10823  ? 195 GLU L CG   1 
ATOM   6259 C CD   . GLU B 2 201 ? 50.58900 14.06500  -7.13800  1.000 30.91877  ? 195 GLU L CD   1 
ATOM   6260 O OE1  . GLU B 2 201 ? 50.00200 13.40200  -8.01900  1.000 30.95888  ? 195 GLU L OE1  1 
ATOM   6261 O OE2  . GLU B 2 201 ? 50.43400 15.29500  -6.98300  1.000 32.63835  ? 195 GLU L OE2  1 
ATOM   6262 H H    . GLU B 2 201 ? 52.02700 9.34000   -6.32600  1.000 22.51283  ? 195 GLU L H    1 
ATOM   6263 H HA   . GLU B 2 201 ? 53.39100 11.50500  -5.43400  1.000 20.23004  ? 195 GLU L HA   1 
ATOM   6264 H HB2  . GLU B 2 201 ? 52.25800 11.89100  -7.45400  1.000 24.70736  ? 195 GLU L HB2  1 
ATOM   6265 H HB3  . GLU B 2 201 ? 50.89000 11.48500  -6.75600  1.000 24.70736  ? 195 GLU L HB3  1 
ATOM   6266 H HG2  . GLU B 2 201 ? 51.16300 13.36300  -5.31900  1.000 30.13345  ? 195 GLU L HG2  1 
ATOM   6267 H HG3  . GLU B 2 201 ? 52.38800 13.80800  -6.22800  1.000 30.13345  ? 195 GLU L HG3  1 
ATOM   6268 N N    . VAL B 2 202 ? 52.29500 11.77100  -3.27700  1.000 18.19678  ? 196 VAL L N    1 
ATOM   6269 C CA   . VAL B 2 202 ? 51.72300 11.82300  -1.93900  1.000 17.94611  ? 196 VAL L CA   1 
ATOM   6270 C C    . VAL B 2 202 ? 51.30900 13.25900  -1.67100  1.000 19.76628  ? 196 VAL L C    1 
ATOM   6271 O O    . VAL B 2 202 ? 52.15800 14.15900  -1.66300  1.000 18.31638  ? 196 VAL L O    1 
ATOM   6272 C CB   . VAL B 2 202 ? 52.72300 11.33600  -0.87900  1.000 16.10580  ? 196 VAL L CB   1 
ATOM   6273 C CG1  . VAL B 2 202 ? 52.11800 11.44300  0.50700   1.000 19.39734  ? 196 VAL L CG1  1 
ATOM   6274 C CG2  . VAL B 2 202 ? 53.16000 9.90200   -1.17800  1.000 19.50865  ? 196 VAL L CG2  1 
ATOM   6275 H H    . VAL B 2 202 ? 53.00700 12.24700  -3.36000  1.000 21.83971  ? 196 VAL L H    1 
ATOM   6276 H HA   . VAL B 2 202 ? 50.93400 11.26000  -1.90000  1.000 21.53890  ? 196 VAL L HA   1 
ATOM   6277 H HB   . VAL B 2 202 ? 53.51200 11.90000  -0.90300  1.000 19.33053  ? 196 VAL L HB   1 
ATOM   6278 H HG11 . VAL B 2 202 ? 52.72000 11.03100  1.14600   1.000 23.28037  ? 196 VAL L HG11 1 
ATOM   6279 H HG12 . VAL B 2 202 ? 51.99300 12.37900  0.72500   1.000 23.28037  ? 196 VAL L HG12 1 
ATOM   6280 H HG13 . VAL B 2 202 ? 51.26400 10.98400  0.51400   1.000 23.28037  ? 196 VAL L HG13 1 
ATOM   6281 H HG21 . VAL B 2 202 ? 53.75300 9.59900   -0.47200  1.000 23.41395  ? 196 VAL L HG21 1 
ATOM   6282 H HG22 . VAL B 2 202 ? 52.37500 9.33400   -1.21700  1.000 23.41395  ? 196 VAL L HG22 1 
ATOM   6283 H HG23 . VAL B 2 202 ? 53.62400 9.88400   -2.03000  1.000 23.41395  ? 196 VAL L HG23 1 
ATOM   6284 N N    . THR B 2 203 ? 50.01500 13.47300  -1.44200  1.000 21.71709  ? 197 THR L N    1 
ATOM   6285 C CA   . THR B 2 203 ? 49.46600 14.79200  -1.15600  1.000 24.93859  ? 197 THR L CA   1 
ATOM   6286 C C    . THR B 2 203 ? 49.05300 14.85600  0.30900   1.000 26.74884  ? 197 THR L C    1 
ATOM   6287 O O    . THR B 2 203 ? 48.27300 14.02100  0.78100   1.000 25.08729  ? 197 THR L O    1 
ATOM   6288 C CB   . THR B 2 203 ? 48.27400 15.10300  -2.06300  1.000 24.89798  ? 197 THR L CB   1 
ATOM   6289 O OG1  . THR B 2 203 ? 48.67900 15.01400  -3.43500  1.000 27.67900  ? 197 THR L OG1  1 
ATOM   6290 C CG2  . THR B 2 203 ? 47.73300 16.51000  -1.78300  1.000 29.08019  ? 197 THR L CG2  1 
ATOM   6291 H H    . THR B 2 203 ? 49.42200 12.85100  -1.44800  1.000 26.06408  ? 197 THR L H    1 
ATOM   6292 H HA   . THR B 2 203 ? 50.15200 15.46100  -1.31000  1.000 29.92987  ? 197 THR L HA   1 
ATOM   6293 H HB   . THR B 2 203 ? 47.56400 14.46500  -1.89200  1.000 29.88115  ? 197 THR L HB   1 
ATOM   6294 H HG1  . THR B 2 203 ? 49.27200 15.58700  -3.59700  1.000 33.21838  ? 197 THR L HG1  1 
ATOM   6295 H HG21 . THR B 2 203 ? 47.04700 16.73600  -2.43100  1.000 34.89980  ? 197 THR L HG21 1 
ATOM   6296 H HG22 . THR B 2 203 ? 47.35000 16.54700  -0.89300  1.000 34.89980  ? 197 THR L HG22 1 
ATOM   6297 H HG23 . THR B 2 203 ? 48.45100 17.15900  -1.84500  1.000 34.89980  ? 197 THR L HG23 1 
ATOM   6298 N N    . GLN B 2 204 ? 49.58600 15.84400  1.02200   1.000 26.95771  ? 198 GLN L N    1 
ATOM   6299 C CA   . GLN B 2 204 ? 49.21300 16.13400  2.40300   1.000 28.06723  ? 198 GLN L CA   1 
ATOM   6300 C C    . GLN B 2 204 ? 49.03000 17.64300  2.49400   1.000 31.86864  ? 198 GLN L C    1 
ATOM   6301 O O    . GLN B 2 204 ? 50.00000 18.39700  2.35900   1.000 28.84676  ? 198 GLN L O    1 
ATOM   6302 C CB   . GLN B 2 204 ? 50.27700 15.64000  3.38100   1.000 31.21795  ? 198 GLN L CB   1 
ATOM   6303 C CG   . GLN B 2 204 ? 49.99400 15.95200  4.83900   1.000 37.18801  ? 198 GLN L CG   1 
ATOM   6304 C CD   . GLN B 2 204 ? 51.21500 15.75900  5.72000   1.000 38.49921  ? 198 GLN L CD   1 
ATOM   6305 O OE1  . GLN B 2 204 ? 52.29900 16.26400  5.42100   1.000 37.66940  ? 198 GLN L OE1  1 
ATOM   6306 N NE2  . GLN B 2 204 ? 51.04500 15.02600  6.81500   1.000 35.77861  ? 198 GLN L NE2  1 
ATOM   6307 H H    . GLN B 2 204 ? 50.18700 16.37800  0.71700   1.000 32.35282  ? 198 GLN L H    1 
ATOM   6308 H HA   . GLN B 2 204 ? 48.38000 15.69500  2.63300   1.000 33.68425  ? 198 GLN L HA   1 
ATOM   6309 H HB2  . GLN B 2 204 ? 50.34900 14.67600  3.29700   1.000 37.46512  ? 198 GLN L HB2  1 
ATOM   6310 H HB3  . GLN B 2 204 ? 51.12300 16.05600  3.15200   1.000 37.46512  ? 198 GLN L HB3  1 
ATOM   6311 H HG2  . GLN B 2 204 ? 49.71000 16.87600  4.91600   1.000 44.62918  ? 198 GLN L HG2  1 
ATOM   6312 H HG3  . GLN B 2 204 ? 49.29500 15.36100  5.15900   1.000 44.62918  ? 198 GLN L HG3  1 
ATOM   6313 H HE21 . GLN B 2 204 ? 50.27400 14.69000  6.99100   1.000 42.93790  ? 198 GLN L HE21 1 
ATOM   6314 H HE22 . GLN B 2 204 ? 51.70700 14.88800  7.34700   1.000 42.93790  ? 198 GLN L HE22 1 
ATOM   6315 N N    . GLY B 2 205 ? 47.79300 18.08000  2.68200   1.000 33.54940  ? 199 GLY L N    1 
ATOM   6316 C CA   . GLY B 2 205 ? 47.53000 19.49800  2.85500   1.000 34.31963  ? 199 GLY L CA   1 
ATOM   6317 C C    . GLY B 2 205 ? 47.89600 20.29300  1.61700   1.000 28.89754  ? 199 GLY L C    1 
ATOM   6318 O O    . GLY B 2 205 ? 47.35200 20.07900  0.52700   1.000 31.25956  ? 199 GLY L O    1 
ATOM   6319 H H    . GLY B 2 205 ? 47.09400 17.58000  2.71400   1.000 40.26286  ? 199 GLY L H    1 
ATOM   6320 H HA2  . GLY B 2 205 ? 46.58700 19.63300  3.03900   1.000 41.18712  ? 199 GLY L HA2  1 
ATOM   6321 H HA3  . GLY B 2 205 ? 48.04800 19.83600  3.60200   1.000 41.18712  ? 199 GLY L HA3  1 
ATOM   6322 N N    . THR B 2 206 ? 48.82900 21.23000  1.77900   1.000 30.44809  ? 200 THR L N    1 
ATOM   6323 C CA   . THR B 2 206 ? 49.22200 22.13600  0.71100   1.000 33.20880  ? 200 THR L CA   1 
ATOM   6324 C C    . THR B 2 206 ? 50.45100 21.65500  -0.04700  1.000 31.74932  ? 200 THR L C    1 
ATOM   6325 O O    . THR B 2 206 ? 51.03400 22.42700  -0.81500  1.000 31.37003  ? 200 THR L O    1 
ATOM   6326 C CB   . THR B 2 206 ? 49.49000 23.53600  1.27400   1.000 32.14775  ? 200 THR L CB   1 
ATOM   6327 O OG1  . THR B 2 206 ? 50.65700 23.50900  2.10900   1.000 34.08934  ? 200 THR L OG1  1 
ATOM   6328 C CG2  . THR B 2 206 ? 48.29800 24.02000  2.08800   1.000 34.05929  ? 200 THR L CG2  1 
ATOM   6329 H H    . THR B 2 206 ? 49.25500 21.36000  2.51500   1.000 36.54128  ? 200 THR L H    1 
ATOM   6330 H HA   . THR B 2 206 ? 48.48600 22.19700  0.08300   1.000 39.85413  ? 200 THR L HA   1 
ATOM   6331 H HB   . THR B 2 206 ? 49.63400 24.15500  0.54200   1.000 38.58087  ? 200 THR L HB   1 
ATOM   6332 H HG1  . THR B 2 206 ? 50.85200 24.28800  2.35600   1.000 40.91078  ? 200 THR L HG1  1 
ATOM   6333 H HG21 . THR B 2 206 ? 48.43500 24.94000  2.36100   1.000 40.87471  ? 200 THR L HG21 1 
ATOM   6334 H HG22 . THR B 2 206 ? 47.48900 23.96600  1.55600   1.000 40.87471  ? 200 THR L HG22 1 
ATOM   6335 H HG23 . THR B 2 206 ? 48.19100 23.46900  2.87900   1.000 40.87471  ? 200 THR L HG23 1 
ATOM   6336 N N    . THR B 2 207 ? 50.85100 20.40000  0.13800   1.000 28.24731  ? 201 THR L N    1 
ATOM   6337 C CA   . THR B 2 207 ? 52.08300 19.88900  -0.44000  1.000 25.72632  ? 201 THR L CA   1 
ATOM   6338 C C    . THR B 2 207 ? 51.82700 18.54700  -1.10300  1.000 25.63822  ? 201 THR L C    1 
ATOM   6339 O O    . THR B 2 207 ? 51.17700 17.67400  -0.51900  1.000 19.07242  ? 201 THR L O    1 
ATOM   6340 C CB   . THR B 2 207 ? 53.17100 19.74100  0.62800   1.000 30.37837  ? 201 THR L CB   1 
ATOM   6341 O OG1  . THR B 2 207 ? 53.35200 20.99400  1.29900   1.000 38.13073  ? 201 THR L OG1  1 
ATOM   6342 C CG2  . THR B 2 207 ? 54.48800 19.30400  -0.00000  1.000 30.45903  ? 201 THR L CG2  1 
ATOM   6343 H H    . THR B 2 207 ? 50.41800 19.82000  0.60300   1.000 33.90035  ? 201 THR L H    1 
ATOM   6344 H HA   . THR B 2 207 ? 52.39100 20.50600  -1.12300  1.000 30.87516  ? 201 THR L HA   1 
ATOM   6345 H HB   . THR B 2 207 ? 52.90600 19.06500  1.27100   1.000 36.45762  ? 201 THR L HB   1 
ATOM   6346 H HG1  . THR B 2 207 ? 53.91200 20.91000  1.91900   1.000 45.76044  ? 201 THR L HG1  1 
ATOM   6347 H HG21 . THR B 2 207 ? 55.18900 19.29800  0.67000   1.000 36.55440  ? 201 THR L HG21 1 
ATOM   6348 H HG22 . THR B 2 207 ? 54.39900 18.41200  -0.37100  1.000 36.55440  ? 201 THR L HG22 1 
ATOM   6349 H HG23 . THR B 2 207 ? 54.73600 19.91700  -0.71000  1.000 36.55440  ? 201 THR L HG23 1 
ATOM   6350 N N    . SER B 2 208 ? 52.33200 18.39700  -2.32400  1.000 23.51744  ? 202 SER L N    1 
ATOM   6351 C CA   . SER B 2 208 ? 52.38600 17.12000  -3.01900  1.000 24.54932  ? 202 SER L CA   1 
ATOM   6352 C C    . SER B 2 208 ? 53.84500 16.79600  -3.30200  1.000 23.92016  ? 202 SER L C    1 
ATOM   6353 O O    . SER B 2 208 ? 54.58800 17.64700  -3.80400  1.000 24.53138  ? 202 SER L O    1 
ATOM   6354 C CB   . SER B 2 208 ? 51.58500 17.15700  -4.31900  1.000 24.74789  ? 202 SER L CB   1 
ATOM   6355 O OG   . SER B 2 208 ? 50.20000 17.25100  -4.04400  1.000 28.97938  ? 202 SER L OG   1 
ATOM   6356 H H    . SER B 2 208 ? 52.66000 19.04500  -2.78400  1.000 28.22450  ? 202 SER L H    1 
ATOM   6357 H HA   . SER B 2 208 ? 52.00800 16.42200  -2.46300  1.000 29.46275  ? 202 SER L HA   1 
ATOM   6358 H HB2  . SER B 2 208 ? 51.85800 17.93000  -4.83800  1.000 29.70104  ? 202 SER L HB2  1 
ATOM   6359 H HB3  . SER B 2 208 ? 51.75400 16.34400  -4.82000  1.000 29.70104  ? 202 SER L HB3  1 
ATOM   6360 H HG   . SER B 2 208 ? 49.76200 17.22700  -4.76000  1.000 34.77883  ? 202 SER L HG   1 
ATOM   6361 N N    . VAL B 2 209 ? 54.25200 15.58000  -2.95300  1.000 16.80405  ? 203 VAL L N    1 
ATOM   6362 C CA   . VAL B 2 209 ? 55.59800 15.08000  -3.20000  1.000 18.29801  ? 203 VAL L CA   1 
ATOM   6363 C C    . VAL B 2 209 ? 55.47900 13.86900  -4.11500  1.000 16.95573  ? 203 VAL L C    1 
ATOM   6364 O O    . VAL B 2 209 ? 54.69800 12.95200  -3.83400  1.000 16.09644  ? 203 VAL L O    1 
ATOM   6365 C CB   . VAL B 2 209 ? 56.31100 14.71000  -1.88700  1.000 19.87752  ? 203 VAL L CB   1 
ATOM   6366 C CG1  . VAL B 2 209 ? 57.67000 14.10400  -2.16600  1.000 20.93926  ? 203 VAL L CG1  1 
ATOM   6367 C CG2  . VAL B 2 209 ? 56.45400 15.93800  -0.99600  1.000 22.89905  ? 203 VAL L CG2  1 
ATOM   6368 H H    . VAL B 2 209 ? 53.74700 15.00700  -2.55700  1.000 20.16843  ? 203 VAL L H    1 
ATOM   6369 H HA   . VAL B 2 209 ? 56.12500 15.75800  -3.65100  1.000 21.96118  ? 203 VAL L HA   1 
ATOM   6370 H HB   . VAL B 2 209 ? 55.77600 14.05000  -1.42000  1.000 23.85660  ? 203 VAL L HB   1 
ATOM   6371 H HG11 . VAL B 2 209 ? 58.14400 13.99100  -1.32700  1.000 25.13068  ? 203 VAL L HG11 1 
ATOM   6372 H HG12 . VAL B 2 209 ? 57.54900 13.24300  -2.59600  1.000 25.13068  ? 203 VAL L HG12 1 
ATOM   6373 H HG13 . VAL B 2 209 ? 58.16700 14.69800  -2.75000  1.000 25.13068  ? 203 VAL L HG13 1 
ATOM   6374 H HG21 . VAL B 2 209 ? 56.91900 15.68600  -0.18300  1.000 27.48243  ? 203 VAL L HG21 1 
ATOM   6375 H HG22 . VAL B 2 209 ? 56.96200 16.61500  -1.47000  1.000 27.48243  ? 203 VAL L HG22 1 
ATOM   6376 H HG23 . VAL B 2 209 ? 55.57100 16.27700  -0.78100  1.000 27.48243  ? 203 VAL L HG23 1 
ATOM   6377 N N    . THR B 2 210 ? 56.23900 13.87400  -5.21000  1.000 14.94462  ? 204 THR L N    1 
ATOM   6378 C CA   . THR B 2 210 ? 56.25200 12.78100  -6.17700  1.000 18.01760  ? 204 THR L CA   1 
ATOM   6379 C C    . THR B 2 210 ? 57.64900 12.17400  -6.21700  1.000 17.94822  ? 204 THR L C    1 
ATOM   6380 O O    . THR B 2 210 ? 58.62400 12.87900  -6.49500  1.000 16.75740  ? 204 THR L O    1 
ATOM   6381 C CB   . THR B 2 210 ? 55.85300 13.27200  -7.57200  1.000 19.63801  ? 204 THR L CB   1 
ATOM   6382 O OG1  . THR B 2 210 ? 54.53700 13.83600  -7.52900  1.000 20.83803  ? 204 THR L OG1  1 
ATOM   6383 C CG2  . THR B 2 210 ? 55.86800 12.13300  -8.58200  1.000 20.35859  ? 204 THR L CG2  1 
ATOM   6384 H H    . THR B 2 210 ? 56.76900 14.51800  -5.41800  1.000 17.93711  ? 204 THR L H    1 
ATOM   6385 H HA   . THR B 2 210 ? 55.62400 12.09800  -5.89400  1.000 21.62469  ? 204 THR L HA   1 
ATOM   6386 H HB   . THR B 2 210 ? 56.49000 13.94400  -7.86100  1.000 23.56918  ? 204 THR L HB   1 
ATOM   6387 H HG1  . THR B 2 210 ? 54.28000 14.02600  -8.30600  1.000 25.00921  ? 204 THR L HG1  1 
ATOM   6388 H HG21 . THR B 2 210 ? 55.55900 12.45000  -9.44500  1.000 24.43388  ? 204 THR L HG21 1 
ATOM   6389 H HG22 . THR B 2 210 ? 56.76900 11.78700  -8.67900  1.000 24.43388  ? 204 THR L HG22 1 
ATOM   6390 H HG23 . THR B 2 210 ? 55.28700 11.41600  -8.28300  1.000 24.43388  ? 204 THR L HG23 1 
ATOM   6391 N N    . LYS B 2 211 ? 57.74000 10.87500  -5.93700  1.000 17.97786  ? 205 LYS L N    1 
ATOM   6392 C CA   . LYS B 2 211 ? 58.96300 10.10000  -6.10100  1.000 14.29442  ? 205 LYS L CA   1 
ATOM   6393 C C    . LYS B 2 211 ? 58.78900 9.18100   -7.30200  1.000 15.92546  ? 205 LYS L C    1 
ATOM   6394 O O    . LYS B 2 211 ? 57.72100 8.59100   -7.48900  1.000 16.51759  ? 205 LYS L O    1 
ATOM   6395 C CB   . LYS B 2 211 ? 59.27400 9.26200   -4.85600  1.000 19.72708  ? 205 LYS L CB   1 
ATOM   6396 C CG   . LYS B 2 211 ? 59.74500 10.05700  -3.64800  1.000 25.48993  ? 205 LYS L CG   1 
ATOM   6397 C CD   . LYS B 2 211 ? 61.12700 10.66900  -3.87200  1.000 29.10887  ? 205 LYS L CD   1 
ATOM   6398 C CE   . LYS B 2 211 ? 62.21200 9.60500   -4.03400  1.000 36.51774  ? 205 LYS L CE   1 
ATOM   6399 N NZ   . LYS B 2 211 ? 63.59100 10.18500  -4.13300  1.000 38.81857  ? 205 LYS L NZ   1 
ATOM   6400 H H    . LYS B 2 211 ? 57.08200 10.40700  -5.64100  1.000 21.57700  ? 205 LYS L H    1 
ATOM   6401 H HA   . LYS B 2 211 ? 59.71400 10.69500  -6.24700  1.000 17.15688  ? 205 LYS L HA   1 
ATOM   6402 H HB2  . LYS B 2 211 ? 58.46900 8.78700   -4.59600  1.000 23.67606  ? 205 LYS L HB2  1 
ATOM   6403 H HB3  . LYS B 2 211 ? 59.97400 8.62900   -5.08000  1.000 23.67606  ? 205 LYS L HB3  1 
ATOM   6404 H HG2  . LYS B 2 211 ? 59.11900 10.77800  -3.47600  1.000 30.59148  ? 205 LYS L HG2  1 
ATOM   6405 H HG3  . LYS B 2 211 ? 59.79500 9.47000   -2.87800  1.000 30.59148  ? 205 LYS L HG3  1 
ATOM   6406 H HD2  . LYS B 2 211 ? 61.11000 11.20800  -4.67800  1.000 34.93421  ? 205 LYS L HD2  1 
ATOM   6407 H HD3  . LYS B 2 211 ? 61.35800 11.22200  -3.10800  1.000 34.93421  ? 205 LYS L HD3  1 
ATOM   6408 H HE2  . LYS B 2 211 ? 62.19200 9.01300   -3.26600  1.000 43.82486  ? 205 LYS L HE2  1 
ATOM   6409 H HE3  . LYS B 2 211 ? 62.04100 9.10100   -4.84500  1.000 43.82486  ? 205 LYS L HE3  1 
ATOM   6410 H HZ1  . LYS B 2 211 ? 64.19700 9.53400   -4.11500  1.000 46.58585  ? 205 LYS L HZ1  1 
ATOM   6411 H HZ2  . LYS B 2 211 ? 63.67600 10.63800  -4.89500  1.000 46.58585  ? 205 LYS L HZ2  1 
ATOM   6412 H HZ3  . LYS B 2 211 ? 63.73800 10.73700  -3.45100  1.000 46.58585  ? 205 LYS L HZ3  1 
ATOM   6413 N N    . SER B 2 212 ? 59.83300 9.05000   -8.11400  1.000 17.40796  ? 206 SER L N    1 
ATOM   6414 C CA   . SER B 2 212 ? 59.73200 8.27200   -9.34000  1.000 16.93706  ? 206 SER L CA   1 
ATOM   6415 C C    . SER B 2 212 ? 61.02000 7.49800   -9.57800  1.000 17.47696  ? 206 SER L C    1 
ATOM   6416 O O    . SER B 2 212 ? 62.05800 7.77100   -8.97300  1.000 17.25758  ? 206 SER L O    1 
ATOM   6417 C CB   . SER B 2 212 ? 59.42900 9.17600   -10.54700 1.000 19.90929  ? 206 SER L CB   1 
ATOM   6418 O OG   . SER B 2 212 ? 60.43800 10.15500  -10.71200 1.000 19.91869  ? 206 SER L OG   1 
ATOM   6419 H H    . SER B 2 212 ? 60.60600 9.40100   -7.97500  1.000 20.89312  ? 206 SER L H    1 
ATOM   6420 H HA   . SER B 2 212 ? 59.01700 7.62400   -9.24400  1.000 20.32805  ? 206 SER L HA   1 
ATOM   6421 H HB2  . SER B 2 212 ? 59.38700 8.62900   -11.34700 1.000 23.89472  ? 206 SER L HB2  1 
ATOM   6422 H HB3  . SER B 2 212 ? 58.57900 9.62000   -10.40300 1.000 23.89472  ? 206 SER L HB3  1 
ATOM   6423 H HG   . SER B 2 212 ? 61.19700 9.80300   -10.63200 1.000 23.90600  ? 206 SER L HG   1 
ATOM   6424 N N    . PHE B 2 213 ? 60.93000 6.49900   -10.45400 1.000 17.64817  ? 207 PHE L N    1 
ATOM   6425 C CA   . PHE B 2 213 ? 62.10900 5.84200   -10.99700 1.000 19.72771  ? 207 PHE L CA   1 
ATOM   6426 C C    . PHE B 2 213 ? 61.83300 5.51000   -12.45600 1.000 21.45799  ? 207 PHE L C    1 
ATOM   6427 O O    . PHE B 2 213 ? 60.68400 5.49600   -12.90500 1.000 20.15744  ? 207 PHE L O    1 
ATOM   6428 C CB   . PHE B 2 213 ? 62.50600 4.57700   -10.20500 1.000 18.29706  ? 207 PHE L CB   1 
ATOM   6429 C CG   . PHE B 2 213 ? 61.51100 3.45100   -10.28900 1.000 17.77699  ? 207 PHE L CG   1 
ATOM   6430 C CD1  . PHE B 2 213 ? 61.54000 2.55300   -11.34600 1.000 19.49949  ? 207 PHE L CD1  1 
ATOM   6431 C CD2  . PHE B 2 213 ? 60.56700 3.27200   -9.29400  1.000 17.55771  ? 207 PHE L CD2  1 
ATOM   6432 C CE1  . PHE B 2 213 ? 60.62800 1.51700   -11.42200 1.000 17.76708  ? 207 PHE L CE1  1 
ATOM   6433 C CE2  . PHE B 2 213 ? 59.65400 2.23000   -9.36100  1.000 15.16670  ? 207 PHE L CE2  1 
ATOM   6434 C CZ   . PHE B 2 213 ? 59.68500 1.35300   -10.42800 1.000 15.76702  ? 207 PHE L CZ   1 
ATOM   6435 H H    . PHE B 2 213 ? 60.18700 6.18300   -10.75000 1.000 21.18137  ? 207 PHE L H    1 
ATOM   6436 H HA   . PHE B 2 213 ? 62.86900 6.44300   -10.95200 1.000 23.67682  ? 207 PHE L HA   1 
ATOM   6437 H HB2  . PHE B 2 213 ? 63.35000 4.24800   -10.55000 1.000 21.96005  ? 207 PHE L HB2  1 
ATOM   6438 H HB3  . PHE B 2 213 ? 62.60000 4.81500   -9.26900  1.000 21.96005  ? 207 PHE L HB3  1 
ATOM   6439 H HD1  . PHE B 2 213 ? 62.18100 2.65000   -12.01300 1.000 23.40295  ? 207 PHE L HD1  1 
ATOM   6440 H HD2  . PHE B 2 213 ? 60.54400 3.85700   -8.57100  1.000 21.07282  ? 207 PHE L HD2  1 
ATOM   6441 H HE1  . PHE B 2 213 ? 60.65100 0.93000   -12.14300 1.000 21.32407  ? 207 PHE L HE1  1 
ATOM   6442 H HE2  . PHE B 2 213 ? 59.02100 2.12200   -8.68800  1.000 18.20361  ? 207 PHE L HE2  1 
ATOM   6443 H HZ   . PHE B 2 213 ? 59.07200 0.65500   -10.47600 1.000 18.92399  ? 207 PHE L HZ   1 
ATOM   6444 N N    . ASN B 2 214 ? 62.90900 5.27000   -13.19900 1.000 24.75872  ? 208 ASN L N    1 
ATOM   6445 C CA   . ASN B 2 214 ? 62.84000 4.82100   -14.58400 1.000 26.98826  ? 208 ASN L CA   1 
ATOM   6446 C C    . ASN B 2 214 ? 63.22200 3.34800   -14.61700 1.000 26.84740  ? 208 ASN L C    1 
ATOM   6447 O O    . ASN B 2 214 ? 64.29700 2.97400   -14.13400 1.000 24.83408  ? 208 ASN L O    1 
ATOM   6448 C CB   . ASN B 2 214 ? 63.77000 5.63700   -15.48200 1.000 31.63790  ? 208 ASN L CB   1 
ATOM   6449 C CG   . ASN B 2 214 ? 63.39900 7.10800   -15.52800 1.000 38.57913  ? 208 ASN L CG   1 
ATOM   6450 O OD1  . ASN B 2 214 ? 62.22800 7.46200   -15.66000 1.000 37.53997  ? 208 ASN L OD1  1 
ATOM   6451 N ND2  . ASN B 2 214 ? 64.40100 7.97300   -15.41600 1.000 46.38793  ? 208 ASN L ND2  1 
ATOM   6452 H H    . ASN B 2 214 ? 63.71500 5.36500   -12.91400 1.000 29.71404  ? 208 ASN L H    1 
ATOM   6453 H HA   . ASN B 2 214 ? 61.93500 4.92600   -14.91900 1.000 32.38949  ? 208 ASN L HA   1 
ATOM   6454 H HB2  . ASN B 2 214 ? 64.67700 5.56600   -15.14500 1.000 37.96905  ? 208 ASN L HB2  1 
ATOM   6455 H HB3  . ASN B 2 214 ? 63.72400 5.28800   -16.38500 1.000 37.96905  ? 208 ASN L HB3  1 
ATOM   6456 H HD21 . ASN B 2 214 ? 64.24400 8.81800   -15.43600 1.000 55.66909  ? 208 ASN L HD21 1 
ATOM   6457 H HD22 . ASN B 2 214 ? 65.20700 7.68800   -15.32300 1.000 55.66909  ? 208 ASN L HD22 1 
ATOM   6458 N N    . ARG B 2 215 ? 62.34300 2.51600   -15.17200 1.000 23.72611  ? 209 ARG L N    1 
ATOM   6459 C CA   . ARG B 2 215 ? 62.62600 1.09000   -15.26600 1.000 25.71642  ? 209 ARG L CA   1 
ATOM   6460 C C    . ARG B 2 215 ? 63.95900 0.87400   -15.97200 1.000 33.17811  ? 209 ARG L C    1 
ATOM   6461 O O    . ARG B 2 215 ? 64.18300 1.38400   -17.07300 1.000 30.85706  ? 209 ARG L O    1 
ATOM   6462 C CB   . ARG B 2 215 ? 61.49900 0.37500   -16.01600 1.000 25.18788  ? 209 ARG L CB   1 
ATOM   6463 C CG   . ARG B 2 215 ? 61.73400 -1.12300  -16.20700 1.000 26.72869  ? 209 ARG L CG   1 
ATOM   6464 C CD   . ARG B 2 215 ? 60.58000 -1.79400  -16.93800 1.000 26.13805  ? 209 ARG L CD   1 
ATOM   6465 N NE   . ARG B 2 215 ? 60.25000 -1.10800  -18.18100 1.000 25.94787  ? 209 ARG L NE   1 
ATOM   6466 C CZ   . ARG B 2 215 ? 60.98400 -1.16200  -19.28400 1.000 28.06814  ? 209 ARG L CZ   1 
ATOM   6467 N NH1  . ARG B 2 215 ? 62.10100 -1.86700  -19.33600 1.000 31.32868  ? 209 ARG L NH1  1 
ATOM   6468 N NH2  . ARG B 2 215 ? 60.59100 -0.48400  -20.35900 1.000 30.76991  ? 209 ARG L NH2  1 
ATOM   6469 H H    . ARG B 2 215 ? 61.58300 2.75200   -15.49700 1.000 28.47491  ? 209 ARG L H    1 
ATOM   6470 H HA   . ARG B 2 215 ? 62.67700 0.70700   -14.37600 1.000 30.86327  ? 209 ARG L HA   1 
ATOM   6471 H HB2  . ARG B 2 215 ? 60.67500 0.48300   -15.51500 1.000 30.22902  ? 209 ARG L HB2  1 
ATOM   6472 H HB3  . ARG B 2 215 ? 61.40800 0.77400   -16.89500 1.000 30.22902  ? 209 ARG L HB3  1 
ATOM   6473 H HG2  . ARG B 2 215 ? 62.54100 -1.25600  -16.72900 1.000 32.07799  ? 209 ARG L HG2  1 
ATOM   6474 H HG3  . ARG B 2 215 ? 61.82800 -1.54500  -15.33800 1.000 32.07799  ? 209 ARG L HG3  1 
ATOM   6475 H HD2  . ARG B 2 215 ? 60.82500 -2.70800  -17.15200 1.000 31.36923  ? 209 ARG L HD2  1 
ATOM   6476 H HD3  . ARG B 2 215 ? 59.79400 -1.78600  -16.36900 1.000 31.36923  ? 209 ARG L HD3  1 
ATOM   6477 H HE   . ARG B 2 215 ? 59.53100 -0.63700  -18.20100 1.000 31.14101  ? 209 ARG L HE   1 
ATOM   6478 H HH11 . ARG B 2 215 ? 62.36600 -2.30400  -18.64500 1.000 37.59799  ? 209 ARG L HH11 1 
ATOM   6479 H HH12 . ARG B 2 215 ? 62.56300 -1.88900  -20.06200 1.000 37.59799  ? 209 ARG L HH12 1 
ATOM   6480 H HH21 . ARG B 2 215 ? 59.86900 -0.01700  -20.33400 1.000 36.92747  ? 209 ARG L HH21 1 
ATOM   6481 H HH22 . ARG B 2 215 ? 61.06000 -0.51100  -21.08000 1.000 36.92747  ? 209 ARG L HH22 1 
ATOM   6482 N N    . GLY B 2 216 ? 64.85500 0.13500   -15.31500 1.000 38.96738  ? 210 GLY L N    1 
ATOM   6483 C CA   . GLY B 2 216 ? 66.14800 -0.19600  -15.87400 1.000 42.42893  ? 210 GLY L CA   1 
ATOM   6484 C C    . GLY B 2 216 ? 67.31000 0.63600   -15.37500 1.000 50.80842  ? 210 GLY L C    1 
ATOM   6485 O O    . GLY B 2 216 ? 68.44100 0.41500   -15.82500 1.000 58.72769  ? 210 GLY L O    1 
ATOM   6486 H H    . GLY B 2 216 ? 64.72600 -0.18900  -14.52900 1.000 46.76442  ? 210 GLY L H    1 
ATOM   6487 H HA2  . GLY B 2 216 ? 66.34300 -1.12400  -15.66800 1.000 50.91829  ? 210 GLY L HA2  1 
ATOM   6488 H HA3  . GLY B 2 216 ? 66.10400 -0.08900  -16.83700 1.000 50.91829  ? 210 GLY L HA3  1 
ATOM   6489 N N    . GLU B 2 217 ? 67.07500 1.57500   -14.46000 1.000 51.33803  ? 211 GLU L N    1 
ATOM   6490 C CA   . GLU B 2 217 ? 68.11600 2.47900   -13.98900 1.000 49.37860  ? 211 GLU L CA   1 
ATOM   6491 C C    . GLU B 2 217 ? 68.03700 2.58700   -12.47600 1.000 56.68818  ? 211 GLU L C    1 
ATOM   6492 O O    . GLU B 2 217 ? 66.98300 2.92900   -11.93200 1.000 56.35880  ? 211 GLU L O    1 
ATOM   6493 C CB   . GLU B 2 217 ? 67.96800 3.87100   -14.61400 1.000 46.32826  ? 211 GLU L CB   1 
ATOM   6494 C CG   . GLU B 2 217 ? 67.47900 3.86900   -16.05400 1.000 47.71815  ? 211 GLU L CG   1 
ATOM   6495 C CD   . GLU B 2 217 ? 67.25100 5.27200   -16.59000 1.000 54.64801  ? 211 GLU L CD   1 
ATOM   6496 O OE1  . GLU B 2 217 ? 67.48300 6.24100   -15.83400 1.000 54.15854  ? 211 GLU L OE1  1 
ATOM   6497 O OE2  . GLU B 2 217 ? 66.83800 5.40600   -17.76200 1.000 54.22905  ? 211 GLU L OE2  1 
ATOM   6498 H H    . GLU B 2 217 ? 66.30800 1.70900   -14.09400 1.000 61.60921  ? 211 GLU L H    1 
ATOM   6499 H HA   . GLU B 2 217 ? 68.98400 2.12000   -14.23100 1.000 59.25789  ? 211 GLU L HA   1 
ATOM   6500 H HB2  . GLU B 2 217 ? 67.33100 4.37900   -14.08900 1.000 55.59749  ? 211 GLU L HB2  1 
ATOM   6501 H HB3  . GLU B 2 217 ? 68.83400 4.30900   -14.59900 1.000 55.59749  ? 211 GLU L HB3  1 
ATOM   6502 H HG2  . GLU B 2 217 ? 68.14200 3.43700   -16.61400 1.000 57.26535  ? 211 GLU L HG2  1 
ATOM   6503 H HG3  . GLU B 2 217 ? 66.63800 3.38800   -16.10300 1.000 57.26535  ? 211 GLU L HG3  1 
ATOM   6504 N N    . CYS B 2 218 ? 69.15200 2.30800   -11.80500 1.000 67.98841  ? 212 CYS L N    1 
ATOM   6505 C CA   . CYS B 2 218 ? 69.21300 2.36200   -10.34800 1.000 72.50806  ? 212 CYS L CA   1 
ATOM   6506 C C    . CYS B 2 218 ? 70.45700 3.10800   -9.87300  1.000 71.22860  ? 212 CYS L C    1 
ATOM   6507 O O    . CYS B 2 218 ? 70.64600 3.32200   -8.67500  1.000 70.27853  ? 212 CYS L O    1 
ATOM   6508 C CB   . CYS B 2 218 ? 69.19600 0.94900   -9.76100  1.000 72.23822  ? 212 CYS L CB   1 
ATOM   6509 S SG   . CYS B 2 218 ? 69.80600 -0.32800  -10.89100 1.000 90.35764  ? 212 CYS L SG   1 
ATOM   6510 H H    . CYS B 2 218 ? 69.89400 2.08200   -12.17500 1.000 81.58967  ? 212 CYS L H    1 
ATOM   6511 H HA   . CYS B 2 218 ? 68.43600 2.84000   -10.01800 1.000 87.01325  ? 212 CYS L HA   1 
ATOM   6512 H HB2  . CYS B 2 218 ? 69.75700 0.93400   -8.97000  1.000 86.68943  ? 212 CYS L HB2  1 
ATOM   6513 H HB3  . CYS B 2 218 ? 68.28300 0.72200   -9.52500  1.000 86.68943  ? 212 CYS L HB3  1 
ATOM   6514 H HG   . CYS B 2 218 ? 70.89100 -0.00900  -11.29200 1.000 108.43274 ? 212 CYS L HG   1 
ATOM   6515 N N    . ALA C 3 3   ? 34.97400 -15.66100 49.03300  1.000 40.09925  ? 3   ALA D N    1 
ATOM   6516 C CA   . ALA C 3 3   ? 35.51500 -16.28100 47.82800  1.000 47.89806  ? 3   ALA D CA   1 
ATOM   6517 C C    . ALA C 3 3   ? 35.97600 -15.21600 46.83500  1.000 47.44824  ? 3   ALA D C    1 
ATOM   6518 O O    . ALA C 3 3   ? 35.31000 -14.19600 46.65400  1.000 44.18722  ? 3   ALA D O    1 
ATOM   6519 C CB   . ALA C 3 3   ? 34.47800 -17.19100 47.18800  1.000 44.89772  ? 3   ALA D CB   1 
ATOM   6520 H HA   . ALA C 3 3   ? 36.28200 -16.82500 48.06700  1.000 57.48124  ? 3   ALA D HA   1 
ATOM   6521 H HB1  . ALA C 3 3   ? 34.85300 -17.57900 46.38200  1.000 53.88084  ? 3   ALA D HB1  1 
ATOM   6522 H HB2  . ALA C 3 3   ? 34.24400 -17.89300 47.81500  1.000 53.88084  ? 3   ALA D HB2  1 
ATOM   6523 H HB3  . ALA C 3 3   ? 33.69100 -16.66800 46.96900  1.000 53.88084  ? 3   ALA D HB3  1 
ATOM   6524 N N    . GLY C 3 4   ? 37.11400 -15.45800 46.19300  1.000 44.61726  ? 4   GLY D N    1 
ATOM   6525 C CA   . GLY C 3 4   ? 37.67500 -14.50300 45.25600  1.000 42.23913  ? 4   GLY D CA   1 
ATOM   6526 C C    . GLY C 3 4   ? 36.93100 -14.47400 43.93900  1.000 36.28767  ? 4   GLY D C    1 
ATOM   6527 O O    . GLY C 3 4   ? 37.05900 -13.52900 43.16100  1.000 37.49989  ? 4   GLY D O    1 
ATOM   6528 H H    . GLY C 3 4   ? 37.58100 -16.17400 46.28700  1.000 53.54428  ? 4   GLY D H    1 
ATOM   6529 H HA2  . GLY C 3 4   ? 37.64200 -13.61600 45.64500  1.000 50.69053  ? 4   GLY D HA2  1 
ATOM   6530 H HA3  . GLY C 3 4   ? 38.60000 -14.73600 45.07800  1.000 50.69053  ? 4   GLY D HA3  1 
HETATM 6531 O O3   . UKD C 3 5   ? 40.41800 -12.28200 40.12400  1.000 28.78701  ? 5   UKD D O3   1 
HETATM 6532 O O4   . UKD C 3 5   ? 38.86300 -12.73600 38.25200  1.000 25.18694  ? 5   UKD D O4   1 
HETATM 6533 P P    . UKD C 3 5   ? 39.82900 -13.35100 39.23500  1.000 31.96023  ? 5   UKD D P    1 
HETATM 6534 O O1   . UKD C 3 5   ? 40.93300 -14.08800 38.51500  1.000 28.75831  ? 5   UKD D O1   1 
HETATM 6535 C CE2  . UKD C 3 5   ? 38.92400 -14.51400 40.25200  1.000 34.36905  ? 5   UKD D CE2  1 
HETATM 6536 N NE1  . UKD C 3 5   ? 39.50500 -15.18600 41.26300  1.000 32.46823  ? 5   UKD D NE1  1 
HETATM 6537 N ND1  . UKD C 3 5   ? 38.45600 -15.97100 41.77400  1.000 33.38794  ? 5   UKD D ND1  1 
HETATM 6538 C CD2  . UKD C 3 5   ? 37.58500 -14.77700 40.03900  1.000 31.12818  ? 5   UKD D CD2  1 
HETATM 6539 N NG   . UKD C 3 5   ? 37.32400 -15.67800 40.99200  1.000 32.68820  ? 5   UKD D NG   1 
HETATM 6540 C CB   . UKD C 3 5   ? 36.10900 -16.39600 41.37400  1.000 35.04899  ? 5   UKD D CB   1 
HETATM 6541 C CA   . UKD C 3 5   ? 35.36400 -15.59300 42.44100  1.000 35.77833  ? 5   UKD D CA   1 
HETATM 6542 N N    . UKD C 3 5   ? 36.14800 -15.51500 43.68500  1.000 34.48657  ? 5   UKD D N    1 
HETATM 6543 C C    . UKD C 3 5   ? 34.02400 -16.22000 42.72100  1.000 36.58921  ? 5   UKD D C    1 
HETATM 6544 O O    . UKD C 3 5   ? 33.84300 -16.93100 43.69500  1.000 36.38764  ? 5   UKD D O    1 
ATOM   6545 N N    . ALA C 3 6   ? 33.07000 -15.92300 41.84800  1.000 32.51649  ? 6   ALA D N    1 
ATOM   6546 C CA   . ALA C 3 6   ? 31.78000 -16.59000 41.84800  1.000 34.65829  ? 6   ALA D CA   1 
ATOM   6547 C C    . ALA C 3 6   ? 31.95000 -18.05800 41.45800  1.000 36.72827  ? 6   ALA D C    1 
ATOM   6548 O O    . ALA C 3 6   ? 33.05700 -18.50800 41.15500  1.000 37.20890  ? 6   ALA D O    1 
ATOM   6549 C CB   . ALA C 3 6   ? 30.83000 -15.88600 40.88800  1.000 33.07818  ? 6   ALA D CB   1 
ATOM   6550 H H    . ALA C 3 6   ? 33.14900 -15.32600 41.23500  1.000 39.02336  ? 6   ALA D H    1 
ATOM   6551 H HA   . ALA C 3 6   ? 31.38900 -16.55200 42.73400  1.000 41.59352  ? 6   ALA D HA   1 
ATOM   6552 H HB1  . ALA C 3 6   ? 29.96900 -16.33300 40.91200  1.000 39.69738  ? 6   ALA D HB1  1 
ATOM   6553 H HB2  . ALA C 3 6   ? 30.73100 -14.96200 41.16300  1.000 39.69738  ? 6   ALA D HB2  1 
ATOM   6554 H HB3  . ALA C 3 6   ? 31.19900 -15.92700 39.99200  1.000 39.69738  ? 6   ALA D HB3  1 
ATOM   6555 N N    . GLY C 3 7   ? 30.84400 -18.80100 41.47100  1.000 37.54762  ? 7   GLY D N    1 
ATOM   6556 C CA   . GLY C 3 7   ? 30.83800 -20.18400 41.04600  1.000 41.19880  ? 7   GLY D CA   1 
ATOM   6557 C C    . GLY C 3 7   ? 31.43700 -21.17500 42.01900  1.000 42.24798  ? 7   GLY D C    1 
ATOM   6558 O O    . GLY C 3 7   ? 31.50600 -22.36800 41.69300  1.000 39.11802  ? 7   GLY D O    1 
ATOM   6559 H H    . GLY C 3 7   ? 30.07500 -18.51500 41.72800  1.000 45.06071  ? 7   GLY D H    1 
ATOM   6560 H HA2  . GLY C 3 7   ? 29.91900 -20.45100 40.88500  1.000 49.44213  ? 7   GLY D HA2  1 
ATOM   6561 H HA3  . GLY C 3 7   ? 31.33500 -20.25200 40.21600  1.000 49.44213  ? 7   GLY D HA3  1 
ATOM   6562 N N    . ALA C 3 8   ? 31.87300 -20.73100 43.19400  1.000 43.17836  ? 8   ALA D N    1 
ATOM   6563 C CA   . ALA C 3 8   ? 32.45500 -21.62900 44.18700  1.000 44.13852  ? 8   ALA D CA   1 
ATOM   6564 C C    . ALA C 3 8   ? 31.42200 -22.00800 45.24400  1.000 45.66859  ? 8   ALA D C    1 
ATOM   6565 O O    . ALA C 3 8   ? 30.49000 -22.76600 44.97200  1.000 47.55894  ? 8   ALA D O    1 
ATOM   6566 C CB   . ALA C 3 8   ? 33.66700 -20.98500 44.83900  1.000 41.68867  ? 8   ALA D CB   1 
ATOM   6567 H H    . ALA C 3 8   ? 31.84300 -19.90900 43.44300  1.000 51.81760  ? 8   ALA D H    1 
ATOM   6568 H HA   . ALA C 3 8   ? 32.74900 -22.44100 43.74500  1.000 52.96979  ? 8   ALA D HA   1 
ATOM   6569 H HB1  . ALA C 3 8   ? 34.02900 -21.59300 45.50300  1.000 50.02998  ? 8   ALA D HB1  1 
ATOM   6570 H HB2  . ALA C 3 8   ? 34.33300 -20.80500 44.15700  1.000 50.02998  ? 8   ALA D HB2  1 
ATOM   6571 H HB3  . ALA C 3 8   ? 33.39400 -20.15600 45.26300  1.000 50.02998  ? 8   ALA D HB3  1 
HETATM 6572 C C1   . EDO D 4 .   ? 48.32700 -12.20700 19.74300  1.000 32.48929  ? 301 EDO H C1   1 
HETATM 6573 O O1   . EDO D 4 .   ? 47.81800 -10.90500 19.42500  1.000 35.37061  ? 301 EDO H O1   1 
HETATM 6574 C C2   . EDO D 4 .   ? 48.62800 -12.95900 18.44900  1.000 36.24960  ? 301 EDO H C2   1 
HETATM 6575 O O2   . EDO D 4 .   ? 49.43900 -14.11000 18.71600  1.000 34.86946  ? 301 EDO H O2   1 
HETATM 6576 H H11  . EDO D 4 .   ? 49.23700 -12.11500 20.34000  1.000 38.99072  ? 301 EDO H H11  1 
HETATM 6577 H H12  . EDO D 4 .   ? 47.59300 -12.76000 20.33200  1.000 38.99072  ? 301 EDO H H12  1 
HETATM 6578 H HO1  . EDO D 4 .   ? 47.61900 -10.42900 20.24300  1.000 42.44830  ? 301 EDO H HO1  1 
HETATM 6579 H H21  . EDO D 4 .   ? 47.69300 -13.27000 17.98000  1.000 43.50309  ? 301 EDO H H21  1 
HETATM 6580 H H22  . EDO D 4 .   ? 49.14900 -12.29700 17.75400  1.000 43.50309  ? 301 EDO H H22  1 
HETATM 6581 H HO2  . EDO D 4 .   ? 49.61600 -14.57900 17.88900  1.000 41.84692  ? 301 EDO H HO2  1 
HETATM 6582 C C1   . EDO E 4 .   ? 52.71200 14.17300  -11.43200 1.000 33.08958  ? 301 EDO L C1   1 
HETATM 6583 O O1   . EDO E 4 .   ? 52.94700 14.49100  -10.05400 1.000 35.32980  ? 301 EDO L O1   1 
HETATM 6584 C C2   . EDO E 4 .   ? 53.40700 12.85900  -11.77500 1.000 29.95921  ? 301 EDO L C2   1 
HETATM 6585 O O2   . EDO E 4 .   ? 53.18600 12.53900  -13.15300 1.000 36.14121  ? 301 EDO L O2   1 
HETATM 6586 H H11  . EDO E 4 .   ? 51.63900 14.08400  -11.61500 1.000 39.71106  ? 301 EDO L H11  1 
HETATM 6587 H H12  . EDO E 4 .   ? 53.09500 14.97300  -12.06800 1.000 39.71106  ? 301 EDO L H12  1 
HETATM 6588 H HO1  . EDO E 4 .   ? 52.52000 15.33200  -9.84000  1.000 42.39934  ? 301 EDO L HO1  1 
HETATM 6589 H H21  . EDO E 4 .   ? 53.01800 12.05900  -11.14200 1.000 35.95462  ? 301 EDO L H21  1 
HETATM 6590 H H22  . EDO E 4 .   ? 54.47900 12.94800  -11.58400 1.000 35.95462  ? 301 EDO L H22  1 
HETATM 6591 H HO2  . EDO E 4 .   ? 53.56900 11.67300  -13.34800 1.000 43.37302  ? 301 EDO L HO2  1 
HETATM 6592 O O    . HOH F 5 .   ? 67.04400 11.85900  5.04300   1.000 41.68890  ? 401 HOH H O    1 
HETATM 6593 O O    . HOH F 5 .   ? 68.83600 11.82900  7.31900   1.000 38.87697  ? 402 HOH H O    1 
HETATM 6594 O O    . HOH F 5 .   ? 45.09900 -18.35800 11.24700  1.000 21.36997  ? 403 HOH H O    1 
HETATM 6595 O O    . HOH F 5 .   ? 41.29500 -11.64800 6.24300   1.000 25.13968  ? 404 HOH H O    1 
HETATM 6596 O O    . HOH F 5 .   ? 49.44700 -25.57900 25.36100  1.000 36.15121  ? 405 HOH H O    1 
HETATM 6597 O O    . HOH F 5 .   ? 31.41600 -27.83000 22.17400  1.000 34.94880  ? 406 HOH H O    1 
HETATM 6598 O O    . HOH F 5 .   ? 72.28600 -6.42500  3.33800   1.000 30.76870  ? 407 HOH H O    1 
HETATM 6599 O O    . HOH F 5 .   ? 39.60600 -16.86400 38.19200  1.000 27.86758  ? 408 HOH H O    1 
HETATM 6600 O O    . HOH F 5 .   ? 28.31000 -25.77500 26.37800  1.000 33.77857  ? 409 HOH H O    1 
HETATM 6601 O O    . HOH F 5 .   ? 48.08800 -12.77100 -5.27000  1.000 23.22907  ? 410 HOH H O    1 
HETATM 6602 O O    . HOH F 5 .   ? 29.43400 -13.54500 19.29400  1.000 33.68917  ? 411 HOH H O    1 
HETATM 6603 O O    . HOH F 5 .   ? 55.51300 0.30400   13.01600  1.000 30.75844  ? 412 HOH H O    1 
HETATM 6604 O O    . HOH F 5 .   ? 49.138   -37.620   36.360    1.000 32.60923  ? 413 HOH H O    1 
HETATM 6605 O O    . HOH F 5 .   ? 44.20900 -10.06200 19.68400  1.000 23.10794  ? 414 HOH H O    1 
HETATM 6606 O O    . HOH F 5 .   ? 50.22300 -5.07900  3.75100   1.000 24.79073  ? 415 HOH H O    1 
HETATM 6607 O O    . HOH F 5 .   ? 54.30600 -14.16700 -5.34200  1.000 26.53938  ? 416 HOH H O    1 
HETATM 6608 O O    . HOH F 5 .   ? 40.91300 -24.89400 5.03800   1.000 21.97703  ? 417 HOH H O    1 
HETATM 6609 O O    . HOH F 5 .   ? 35.02700 -5.98400  23.74800  1.000 21.83876  ? 418 HOH H O    1 
HETATM 6610 O O    . HOH F 5 .   ? 45.13300 -20.56800 -0.01200  1.000 22.48000  ? 419 HOH H O    1 
HETATM 6611 O O    . HOH F 5 .   ? 61.44600 3.81000   10.11600  1.000 27.47827  ? 420 HOH H O    1 
HETATM 6612 O O    . HOH F 5 .   ? 42.72700 -29.86500 28.87800  1.000 32.55826  ? 421 HOH H O    1 
HETATM 6613 O O    . HOH F 5 .   ? 33.60500 -29.25300 31.26100  1.000 33.72973  ? 422 HOH H O    1 
HETATM 6614 O O    . HOH F 5 .   ? 67.25400 1.57100   12.07600  1.000 34.68883  ? 423 HOH H O    1 
HETATM 6615 O O    . HOH F 5 .   ? 47.53900 -19.27200 14.23700  1.000 28.33054  ? 424 HOH H O    1 
HETATM 6616 O O    . HOH F 5 .   ? 43.70800 -28.17400 17.34600  1.000 36.84904  ? 425 HOH H O    1 
HETATM 6617 O O    . HOH F 5 .   ? 53.25000 -4.27200  0.60700   1.000 20.91837  ? 426 HOH H O    1 
HETATM 6618 O O    . HOH F 5 .   ? 49.94000 -12.84200 31.28900  1.000 28.25839  ? 427 HOH H O    1 
HETATM 6619 O O    . HOH F 5 .   ? 39.21100 -32.95900 34.54000  1.000 37.75749  ? 428 HOH H O    1 
HETATM 6620 O O    . HOH F 5 .   ? 30.85400 -12.53100 26.13700  1.000 29.72015  ? 429 HOH H O    1 
HETATM 6621 O O    . HOH F 5 .   ? 51.74200 -7.34300  10.13200  1.000 18.64795  ? 430 HOH H O    1 
HETATM 6622 O O    . HOH F 5 .   ? 49.90300 -12.05700 8.46800   1.000 21.84959  ? 431 HOH H O    1 
HETATM 6623 O O    . HOH F 5 .   ? 47.83600 -24.04200 8.40000   1.000 24.13014  ? 432 HOH H O    1 
HETATM 6624 O O    . HOH F 5 .   ? 46.931   -28.771   42.364    1.000 36.86936  ? 433 HOH H O    1 
HETATM 6625 O O    . HOH F 5 .   ? 36.05200 -30.12400 35.33800  1.000 37.32891  ? 434 HOH H O    1 
HETATM 6626 O O    . HOH F 5 .   ? 37.40000 -8.85000  11.75900  1.000 27.96841  ? 435 HOH H O    1 
HETATM 6627 O O    . HOH F 5 .   ? 58.21200 -6.95000  12.80200  1.000 27.89979  ? 436 HOH H O    1 
HETATM 6628 O O    . HOH F 5 .   ? 59.25800 1.48800   14.54100  1.000 33.08783  ? 437 HOH H O    1 
HETATM 6629 O O    . HOH F 5 .   ? 33.999   -28.708   7.693     1.000 32.49839  ? 438 HOH H O    1 
HETATM 6630 O O    . HOH F 5 .   ? 54.23600 -17.79800 -1.95400  1.000 25.56137  ? 439 HOH H O    1 
HETATM 6631 O O    . HOH F 5 .   ? 53.52900 -17.54300 11.81700  1.000 19.32787  ? 440 HOH H O    1 
HETATM 6632 O O    . HOH F 5 .   ? 37.55100 -16.10000 8.06700   1.000 28.94046  ? 441 HOH H O    1 
HETATM 6633 O O    . HOH F 5 .   ? 44.50200 -26.22300 12.30300  1.000 35.87029  ? 442 HOH H O    1 
HETATM 6634 O O    . HOH F 5 .   ? 35.87400 -10.02000 18.89000  1.000 20.34864  ? 443 HOH H O    1 
HETATM 6635 O O    . HOH F 5 .   ? 24.24300 -20.57200 22.54200  1.000 36.13971  ? 444 HOH H O    1 
HETATM 6636 O O    . HOH F 5 .   ? 38.97700 -28.04600 9.62700   1.000 31.18895  ? 445 HOH H O    1 
HETATM 6637 O O    . HOH F 5 .   ? 44.10000 -17.99400 -5.28800  1.000 28.58910  ? 446 HOH H O    1 
HETATM 6638 O O    . HOH F 5 .   ? 44.19500 -15.91200 8.08900   1.000 17.61567  ? 447 HOH H O    1 
HETATM 6639 O O    . HOH F 5 .   ? 63.46400 -7.30200  14.49100  1.000 20.40652  ? 448 HOH H O    1 
HETATM 6640 O O    . HOH F 5 .   ? 69.32000 -12.98500 10.70700  1.000 26.73884  ? 449 HOH H O    1 
HETATM 6641 O O    . HOH F 5 .   ? 37.31400 -19.91800 40.34300  1.000 32.87839  ? 450 HOH H O    1 
HETATM 6642 O O    . HOH F 5 .   ? 67.54800 -1.46900  16.70600  1.000 28.72814  ? 451 HOH H O    1 
HETATM 6643 O O    . HOH F 5 .   ? 35.14800 -13.71500 16.10900  1.000 25.46036  ? 452 HOH H O    1 
HETATM 6644 O O    . HOH F 5 .   ? 47.29900 -19.56300 11.75200  1.000 25.25959  ? 453 HOH H O    1 
HETATM 6645 O O    . HOH F 5 .   ? 41.33800 -5.18600  17.96800  1.000 31.45090  ? 454 HOH H O    1 
HETATM 6646 O O    . HOH F 5 .   ? 68.62300 -8.91500  -1.98400  1.000 32.45006  ? 455 HOH H O    1 
HETATM 6647 O O    . HOH F 5 .   ? 53.85400 -9.64700  11.02700  1.000 27.70975  ? 456 HOH H O    1 
HETATM 6648 O O    . HOH F 5 .   ? 73.60300 -3.63600  3.20500   1.000 35.98775  ? 457 HOH H O    1 
HETATM 6649 O O    . HOH F 5 .   ? 29.221   -29.071   9.933     1.000 36.37882  ? 458 HOH H O    1 
HETATM 6650 O O    . HOH F 5 .   ? 59.28000 -9.63900  15.20600  1.000 33.41102  ? 459 HOH H O    1 
HETATM 6651 O O    . HOH F 5 .   ? 40.54300 -26.83200 43.06300  1.000 35.61863  ? 460 HOH H O    1 
HETATM 6652 O O    . HOH F 5 .   ? 43.61700 -27.17100 8.72400   1.000 36.77968  ? 461 HOH H O    1 
HETATM 6653 O O    . HOH F 5 .   ? 48.97300 -10.30900 -6.90500  1.000 28.69037  ? 462 HOH H O    1 
HETATM 6654 O O    . HOH F 5 .   ? 42.26500 -8.38300  46.25400  1.000 37.96947  ? 463 HOH H O    1 
HETATM 6655 O O    . HOH F 5 .   ? 60.43900 -14.07100 12.29400  1.000 22.55980  ? 464 HOH H O    1 
HETATM 6656 O O    . HOH F 5 .   ? 43.11300 -18.45500 -0.26700  1.000 24.68081  ? 465 HOH H O    1 
HETATM 6657 O O    . HOH F 5 .   ? 39.61000 -17.18100 3.31200   1.000 28.42060  ? 466 HOH H O    1 
HETATM 6658 O O    . HOH F 5 .   ? 48.44600 -17.39800 15.74100  1.000 25.95950  ? 467 HOH H O    1 
HETATM 6659 O O    . HOH F 5 .   ? 51.95000 -17.00300 29.79900  1.000 34.22742  ? 468 HOH H O    1 
HETATM 6660 O O    . HOH F 5 .   ? 36.69000 -29.12400 25.85000  1.000 30.35724  ? 469 HOH H O    1 
HETATM 6661 O O    . HOH F 5 .   ? 39.36800 -15.41800 34.55200  1.000 22.19668  ? 470 HOH H O    1 
HETATM 6662 O O    . HOH F 5 .   ? 63.85600 8.46900   -1.62200  1.000 36.96877  ? 471 HOH H O    1 
HETATM 6663 O O    . HOH F 5 .   ? 35.68400 -12.73200 12.44800  1.000 27.58045  ? 472 HOH H O    1 
HETATM 6664 O O    . HOH F 5 .   ? 40.96600 -15.86600 1.42300   1.000 25.37031  ? 473 HOH H O    1 
HETATM 6665 O O    . HOH F 5 .   ? 65.81800 5.24500   11.42600  1.000 33.17896  ? 474 HOH H O    1 
HETATM 6666 O O    . HOH F 5 .   ? 56.05600 -9.43700  12.64200  1.000 25.25930  ? 475 HOH H O    1 
HETATM 6667 O O    . HOH F 5 .   ? 46.99400 -29.84000 37.31000  1.000 41.89812  ? 476 HOH H O    1 
HETATM 6668 O O    . HOH F 5 .   ? 55.88100 -2.64300  13.04700  1.000 23.27832  ? 477 HOH H O    1 
HETATM 6669 O O    . HOH F 5 .   ? 42.01100 -25.95900 16.39200  1.000 33.56921  ? 478 HOH H O    1 
HETATM 6670 O O    . HOH F 5 .   ? 71.65200 -0.18400  11.40600  1.000 40.04813  ? 479 HOH H O    1 
HETATM 6671 O O    . HOH F 5 .   ? 51.47600 -5.96600  1.09200   1.000 28.44146  ? 480 HOH H O    1 
HETATM 6672 O O    . HOH F 5 .   ? 42.71300 -15.54300 42.53900  1.000 34.66922  ? 481 HOH H O    1 
HETATM 6673 O O    . HOH F 5 .   ? 51.93200 -25.42200 12.07200  1.000 32.62098  ? 482 HOH H O    1 
HETATM 6674 O O    . HOH F 5 .   ? 26.78900 -22.01600 31.40000  1.000 37.91879  ? 483 HOH H O    1 
HETATM 6675 O O    . HOH F 5 .   ? 50.55000 -35.83300 36.06900  1.000 35.07922  ? 484 HOH H O    1 
HETATM 6676 O O    . HOH F 5 .   ? 71.42100 -3.30600  2.01700   1.000 39.60721  ? 485 HOH H O    1 
HETATM 6677 O O    . HOH F 5 .   ? 48.76900 -8.41500  9.89900   1.000 24.18901  ? 486 HOH H O    1 
HETATM 6678 O O    . HOH F 5 .   ? 62.383   -24.857   12.788    1.000 30.54912  ? 487 HOH H O    1 
HETATM 6679 O O    . HOH F 5 .   ? 50.44600 -7.26300  -2.91700  1.000 22.41841  ? 488 HOH H O    1 
HETATM 6680 O O    . HOH F 5 .   ? 42.66700 -7.14400  16.60700  1.000 27.70960  ? 489 HOH H O    1 
HETATM 6681 O O    . HOH F 5 .   ? 38.46700 -31.51400 36.62100  1.000 36.35704  ? 490 HOH H O    1 
HETATM 6682 O O    . HOH F 5 .   ? 30.53200 -15.17600 30.76500  1.000 26.50772  ? 491 HOH H O    1 
HETATM 6683 O O    . HOH F 5 .   ? 77.82000 -7.38900  8.00100   1.000 42.28916  ? 492 HOH H O    1 
HETATM 6684 O O    . HOH F 5 .   ? 44.84900 -7.44400  -4.74100  1.000 23.93877  ? 493 HOH H O    1 
HETATM 6685 O O    . HOH F 5 .   ? 36.38400 -19.99200 3.18000   1.000 26.81072  ? 494 HOH H O    1 
HETATM 6686 O O    . HOH F 5 .   ? 45.80300 -26.67700 4.23400   1.000 30.44773  ? 495 HOH H O    1 
HETATM 6687 O O    . HOH F 5 .   ? 45.67900 -10.70200 -6.33200  1.000 25.81046  ? 496 HOH H O    1 
HETATM 6688 O O    . HOH F 5 .   ? 25.57700 -14.34100 29.08500  1.000 39.61984  ? 497 HOH H O    1 
HETATM 6689 O O    . HOH F 5 .   ? 31.85700 -29.20600 13.85000  1.000 35.30910  ? 498 HOH H O    1 
HETATM 6690 O O    . HOH F 5 .   ? 59.70000 -6.13500  -3.85500  1.000 21.58001  ? 499 HOH H O    1 
HETATM 6691 O O    . HOH F 5 .   ? 48.33500 -14.08300 15.84800  1.000 32.06076  ? 500 HOH H O    1 
HETATM 6692 O O    . HOH F 5 .   ? 42.70100 -10.12800 16.64900  1.000 26.76991  ? 501 HOH H O    1 
HETATM 6693 O O    . HOH F 5 .   ? 40.70400 -31.87200 28.57000  1.000 34.23876  ? 502 HOH H O    1 
HETATM 6694 O O    . HOH F 5 .   ? 36.74400 -30.70500 32.65800  1.000 29.35788  ? 503 HOH H O    1 
HETATM 6695 O O    . HOH F 5 .   ? 49.40600 -23.81600 42.07300  1.000 41.27842  ? 504 HOH H O    1 
HETATM 6696 O O    . HOH F 5 .   ? 75.52300 7.72800   -2.49600  1.000 41.35957  ? 505 HOH H O    1 
HETATM 6697 O O    . HOH F 5 .   ? 31.26100 -19.11100 6.73000   1.000 26.83801  ? 506 HOH H O    1 
HETATM 6698 O O    . HOH F 5 .   ? 80.34700 -5.07500  1.13900   1.000 51.79930  ? 507 HOH H O    1 
HETATM 6699 O O    . HOH F 5 .   ? 27.20700 -18.20700 17.95700  1.000 39.84927  ? 508 HOH H O    1 
HETATM 6700 O O    . HOH F 5 .   ? 47.68500 -8.10900  -5.72000  1.000 28.25024  ? 509 HOH H O    1 
HETATM 6701 O O    . HOH F 5 .   ? 35.07200 -22.97700 42.28500  1.000 31.23725  ? 510 HOH H O    1 
HETATM 6702 O O    . HOH F 5 .   ? 69.97200 -15.88100 3.85600   1.000 32.91102  ? 511 HOH H O    1 
HETATM 6703 O O    . HOH F 5 .   ? 68.02300 5.27800   10.93100  1.000 36.53900  ? 512 HOH H O    1 
HETATM 6704 O O    . HOH F 5 .   ? 47.47800 -22.35800 10.86700  1.000 28.65923  ? 513 HOH H O    1 
HETATM 6705 O O    . HOH F 5 .   ? 60.35300 -3.93300  15.54400  1.000 32.96043  ? 514 HOH H O    1 
HETATM 6706 O O    . HOH F 5 .   ? 28.71200 -28.35200 22.56600  1.000 38.50986  ? 515 HOH H O    1 
HETATM 6707 O O    . HOH F 5 .   ? 69.61500 -15.19700 9.17600   1.000 33.19009  ? 516 HOH H O    1 
HETATM 6708 O O    . HOH F 5 .   ? 50.30700 -23.11000 13.19100  1.000 33.43010  ? 517 HOH H O    1 
HETATM 6709 O O    . HOH F 5 .   ? 60.561   -19.135   -0.845    1.000 29.56990  ? 518 HOH H O    1 
HETATM 6710 O O    . HOH F 5 .   ? 39.511   -11.805   -8.948    1.000 29.94916  ? 519 HOH H O    1 
HETATM 6711 O O    . HOH F 5 .   ? 60.87700 -6.09700  14.41600  1.000 32.28149  ? 520 HOH H O    1 
HETATM 6712 O O    . HOH F 5 .   ? 73.95800 1.23800   11.73600  1.000 40.96926  ? 521 HOH H O    1 
HETATM 6713 O O    . HOH F 5 .   ? 43.80100 -10.71300 14.50400  1.000 33.14862  ? 522 HOH H O    1 
HETATM 6714 O O    . HOH F 5 .   ? 46.91700 -7.10000  11.09400  1.000 31.39866  ? 523 HOH H O    1 
HETATM 6715 O O    . HOH F 5 .   ? 51.57400 -12.73400 15.10900  1.000 33.50090  ? 524 HOH H O    1 
HETATM 6716 O O    . HOH F 5 .   ? 33.613   -19.602   5.110     1.000 33.38183  ? 525 HOH H O    1 
HETATM 6717 O O    . HOH F 5 .   ? 69.63800 1.09300   12.95300  1.000 32.61785  ? 526 HOH H O    1 
HETATM 6718 O O    . HOH F 5 .   ? 66.43800 -6.24300  -5.76300  1.000 32.37871  ? 527 HOH H O    1 
HETATM 6719 O O    . HOH F 5 .   ? 69.86300 -0.11400  15.10200  1.000 37.46006  ? 528 HOH H O    1 
HETATM 6720 O O    . HOH G 5 .   ? 51.96400 16.15200  33.08800  1.000 41.74797  ? 401 HOH L O    1 
HETATM 6721 O O    . HOH G 5 .   ? 29.12600 -3.50000  41.80400  1.000 29.49911  ? 402 HOH L O    1 
HETATM 6722 O O    . HOH G 5 .   ? 48.97200 -5.08000  -15.30100 1.000 28.82736  ? 403 HOH L O    1 
HETATM 6723 O O    . HOH G 5 .   ? 45.51700 7.21800   2.33100   1.000 34.97919  ? 404 HOH L O    1 
HETATM 6724 O O    . HOH G 5 .   ? 41.95100 -3.80500  20.89700  1.000 25.30876  ? 405 HOH L O    1 
HETATM 6725 O O    . HOH G 5 .   ? 46.91700 -4.83200  17.10800  1.000 36.95869  ? 406 HOH L O    1 
HETATM 6726 O O    . HOH G 5 .   ? 48.09900 18.35000  14.53900  1.000 34.60082  ? 407 HOH L O    1 
HETATM 6727 O O    . HOH G 5 .   ? 36.02100 11.24400  22.16000  1.000 37.53048  ? 408 HOH L O    1 
HETATM 6728 O O    . HOH G 5 .   ? 62.86700 -5.07300  -16.06600 1.000 37.09073  ? 409 HOH L O    1 
HETATM 6729 O O    . HOH G 5 .   ? 51.44000 2.47100   22.47100  1.000 25.71671  ? 410 HOH L O    1 
HETATM 6730 O O    . HOH G 5 .   ? 55.22400 11.01800  -13.45700 1.000 32.49024  ? 411 HOH L O    1 
HETATM 6731 O O    . HOH G 5 .   ? 51.69800 3.02700   28.57900  1.000 27.21754  ? 412 HOH L O    1 
HETATM 6732 O O    . HOH G 5 .   ? 45.46700 11.39600  16.50800  1.000 32.97841  ? 413 HOH L O    1 
HETATM 6733 O O    . HOH G 5 .   ? 53.57400 3.68200   13.12600  1.000 26.43811  ? 414 HOH L O    1 
HETATM 6734 O O    . HOH G 5 .   ? 39.98700 -1.40900  14.81700  1.000 36.45906  ? 415 HOH L O    1 
HETATM 6735 O O    . HOH G 5 .   ? 54.625   16.279    -6.619    1.000 22.05773  ? 416 HOH L O    1 
HETATM 6736 O O    . HOH G 5 .   ? 66.21200 -7.28800  -8.24200  1.000 36.47087  ? 417 HOH L O    1 
HETATM 6737 O O    . HOH G 5 .   ? 51.39800 -7.10200  -5.27500  1.000 19.63753  ? 418 HOH L O    1 
HETATM 6738 O O    . HOH G 5 .   ? 63.35700 12.01100  -2.24600  1.000 33.33940  ? 419 HOH L O    1 
HETATM 6739 O O    . HOH G 5 .   ? 39.52400 6.77900   37.88100  1.000 30.46883  ? 420 HOH L O    1 
HETATM 6740 O O    . HOH G 5 .   ? 25.86600 -1.16200  30.37100  1.000 34.54040  ? 421 HOH L O    1 
HETATM 6741 O O    . HOH G 5 .   ? 48.27700 -3.93500  -5.17600  1.000 18.53661  ? 422 HOH L O    1 
HETATM 6742 O O    . HOH G 5 .   ? 42.60900 3.00900   -7.15900  1.000 33.65977  ? 423 HOH L O    1 
HETATM 6743 O O    . HOH G 5 .   ? 46.47800 -0.27900  11.15300  1.000 33.01023  ? 424 HOH L O    1 
HETATM 6744 O O    . HOH G 5 .   ? 37.90700 -2.52000  20.56500  1.000 31.50163  ? 425 HOH L O    1 
HETATM 6745 O O    . HOH G 5 .   ? 63.63000 -4.90300  -11.43400 1.000 29.62971  ? 426 HOH L O    1 
HETATM 6746 O O    . HOH G 5 .   ? 63.82600 -11.13000 -13.64000 1.000 33.13887  ? 427 HOH L O    1 
HETATM 6747 O O    . HOH G 5 .   ? 45.32000 9.10600   37.45600  1.000 32.49847  ? 428 HOH L O    1 
HETATM 6748 O O    . HOH G 5 .   ? 22.64100 -7.25900  33.51200  1.000 36.21945  ? 429 HOH L O    1 
HETATM 6749 O O    . HOH G 5 .   ? 59.52700 -7.56800  -5.82800  1.000 18.86787  ? 430 HOH L O    1 
HETATM 6750 O O    . HOH G 5 .   ? 48.44000 -5.34900  -2.78300  1.000 25.07912  ? 431 HOH L O    1 
HETATM 6751 O O    . HOH G 5 .   ? 58.04500 2.54900   18.54100  1.000 38.99095  ? 432 HOH L O    1 
HETATM 6752 O O    . HOH G 5 .   ? 56.54900 14.56100  2.08800   1.000 33.09882  ? 433 HOH L O    1 
HETATM 6753 O O    . HOH G 5 .   ? 50.76800 15.82800  22.15900  1.000 34.13924  ? 434 HOH L O    1 
HETATM 6754 O O    . HOH G 5 .   ? 45.74300 16.52900  3.45400   1.000 32.57928  ? 435 HOH L O    1 
HETATM 6755 O O    . HOH G 5 .   ? 46.08400 2.44900   -8.25500  1.000 21.14684  ? 436 HOH L O    1 
HETATM 6756 O O    . HOH G 5 .   ? 45.62400 7.12800   5.51200   1.000 33.10981  ? 437 HOH L O    1 
HETATM 6757 O O    . HOH G 5 .   ? 51.99200 7.56900   20.31200  1.000 25.86734  ? 438 HOH L O    1 
HETATM 6758 O O    . HOH G 5 .   ? 43.60100 14.62800  8.50900   1.000 46.71944  ? 439 HOH L O    1 
HETATM 6759 O O    . HOH G 5 .   ? 40.64900 -1.18800  19.15400  1.000 34.59871  ? 440 HOH L O    1 
HETATM 6760 O O    . HOH G 5 .   ? 26.13500 -2.45100  44.09000  1.000 35.46147  ? 441 HOH L O    1 
HETATM 6761 O O    . HOH G 5 .   ? 50.22500 -1.89600  0.48900   1.000 22.18000  ? 442 HOH L O    1 
HETATM 6762 O O    . HOH G 5 .   ? 51.83200 -0.44100  30.35500  1.000 37.72949  ? 443 HOH L O    1 
HETATM 6763 O O    . HOH G 5 .   ? 42.88700 6.84600   -9.54400  1.000 34.71041  ? 444 HOH L O    1 
HETATM 6764 O O    . HOH G 5 .   ? 50.81000 -3.05200  -25.45500 1.000 34.82770  ? 445 HOH L O    1 
HETATM 6765 O O    . HOH G 5 .   ? 52.41500 -3.51300  3.00300   1.000 22.98961  ? 446 HOH L O    1 
HETATM 6766 O O    . HOH G 5 .   ? 63.97200 6.60000   -7.42600  1.000 31.03966  ? 447 HOH L O    1 
HETATM 6767 O O    . HOH G 5 .   ? 39.42400 13.88300  31.71600  1.000 36.95936  ? 448 HOH L O    1 
HETATM 6768 O O    . HOH G 5 .   ? 52.602   17.193    -10.348   1.000 37.56960  ? 449 HOH L O    1 
HETATM 6769 O O    . HOH G 5 .   ? 49.82000 -2.73000  26.83400  1.000 28.12897  ? 450 HOH L O    1 
HETATM 6770 O O    . HOH G 5 .   ? 55.42300 5.70500   12.11200  1.000 24.05771  ? 451 HOH L O    1 
HETATM 6771 O O    . HOH G 5 .   ? 50.62000 -1.00800  13.65100  1.000 33.01880  ? 452 HOH L O    1 
HETATM 6772 O O    . HOH G 5 .   ? 58.88400 11.82000  8.29700   1.000 24.73939  ? 453 HOH L O    1 
HETATM 6773 O O    . HOH G 5 .   ? 45.16700 7.41500   -0.93800  1.000 31.10900  ? 454 HOH L O    1 
HETATM 6774 O O    . HOH G 5 .   ? 57.16300 17.77300  8.79900   1.000 33.30998  ? 455 HOH L O    1 
HETATM 6775 O O    . HOH G 5 .   ? 60.16300 12.42100  1.09900   1.000 25.21977  ? 456 HOH L O    1 
HETATM 6776 O O    . HOH G 5 .   ? 46.94400 4.73000   40.68500  1.000 36.28898  ? 457 HOH L O    1 
HETATM 6777 O O    . HOH G 5 .   ? 62.97700 -3.00200  -12.82300 1.000 28.62868  ? 458 HOH L O    1 
HETATM 6778 O O    . HOH G 5 .   ? 46.53300 5.51800   -8.06100  1.000 22.69782  ? 459 HOH L O    1 
HETATM 6779 O O    . HOH G 5 .   ? 46.743   1.134     43.788    1.000 33.33911  ? 460 HOH L O    1 
HETATM 6780 O O    . HOH G 5 .   ? 48.25900 -8.71200  31.97100  1.000 29.31013  ? 461 HOH L O    1 
HETATM 6781 O O    . HOH G 5 .   ? 36.99400 11.29300  27.80900  1.000 37.15008  ? 462 HOH L O    1 
HETATM 6782 O O    . HOH G 5 .   ? 29.94500 -11.87000 28.50200  1.000 31.73938  ? 463 HOH L O    1 
HETATM 6783 O O    . HOH G 5 .   ? 51.60700 -9.71800  23.31700  1.000 36.65044  ? 464 HOH L O    1 
HETATM 6784 O O    . HOH G 5 .   ? 31.04700 -17.61300 32.23700  1.000 26.06676  ? 465 HOH L O    1 
HETATM 6785 O O    . HOH G 5 .   ? 44.12900 3.22500   41.08100  1.000 35.93944  ? 466 HOH L O    1 
HETATM 6786 O O    . HOH G 5 .   ? 43.78300 -0.34300  0.15800   1.000 31.20980  ? 467 HOH L O    1 
HETATM 6787 O O    . HOH G 5 .   ? 37.66400 1.19500   38.23100  1.000 24.35662  ? 468 HOH L O    1 
HETATM 6788 O O    . HOH G 5 .   ? 38.51700 13.22600  21.46100  1.000 31.90934  ? 469 HOH L O    1 
HETATM 6789 O O    . HOH G 5 .   ? 65.74700 -9.82600  -7.12100  1.000 29.42933  ? 470 HOH L O    1 
HETATM 6790 O O    . HOH G 5 .   ? 37.13300 -10.30500 45.27700  1.000 38.77923  ? 471 HOH L O    1 
HETATM 6791 O O    . HOH G 5 .   ? 46.47600 3.38400   12.21000  1.000 34.57904  ? 472 HOH L O    1 
HETATM 6792 O O    . HOH G 5 .   ? 29.65900 -5.85700  27.54400  1.000 29.60886  ? 473 HOH L O    1 
HETATM 6793 O O    . HOH G 5 .   ? 58.86400 -3.58300  -4.88500  1.000 16.58778  ? 474 HOH L O    1 
HETATM 6794 O O    . HOH G 5 .   ? 49.25900 -4.61100  25.05200  1.000 25.68780  ? 475 HOH L O    1 
HETATM 6795 O O    . HOH G 5 .   ? 51.21800 21.10400  13.46600  1.000 34.09752  ? 476 HOH L O    1 
HETATM 6796 O O    . HOH G 5 .   ? 65.45700 5.68500   -11.97500 1.000 26.02642  ? 477 HOH L O    1 
HETATM 6797 O O    . HOH G 5 .   ? 64.53500 -0.62200  -12.55200 1.000 32.48905  ? 478 HOH L O    1 
HETATM 6798 O O    . HOH G 5 .   ? 63.95200 3.71500   -6.30300  1.000 28.75024  ? 479 HOH L O    1 
HETATM 6799 O O    . HOH G 5 .   ? 55.56700 1.78600   15.06200  1.000 34.98907  ? 480 HOH L O    1 
HETATM 6800 O O    . HOH G 5 .   ? 49.11100 -9.18000  -18.61000 1.000 38.97699  ? 481 HOH L O    1 
HETATM 6801 O O    . HOH G 5 .   ? 48.266   -5.376    -24.647   1.000 27.95904  ? 482 HOH L O    1 
HETATM 6802 O O    . HOH G 5 .   ? 45.54100 14.48900  1.69700   1.000 32.76982  ? 483 HOH L O    1 
HETATM 6803 O O    . HOH G 5 .   ? 28.55600 -10.38100 45.36500  1.000 33.05905  ? 484 HOH L O    1 
HETATM 6804 O O    . HOH G 5 .   ? 45.82200 -0.62800  6.97500   1.000 26.48958  ? 485 HOH L O    1 
HETATM 6805 O O    . HOH G 5 .   ? 52.68200 9.61400   37.67900  1.000 36.67941  ? 486 HOH L O    1 
HETATM 6806 O O    . HOH G 5 .   ? 50.58000 -10.42400 17.39700  1.000 37.88769  ? 487 HOH L O    1 
HETATM 6807 O O    . HOH G 5 .   ? 38.72500 10.28200  18.55600  1.000 36.19917  ? 488 HOH L O    1 
HETATM 6808 O O    . HOH G 5 .   ? 27.53900 -10.24200 40.40700  1.000 25.19763  ? 489 HOH L O    1 
HETATM 6809 O O    . HOH G 5 .   ? 33.42400 7.79000   20.85600  1.000 33.24002  ? 490 HOH L O    1 
HETATM 6810 O O    . HOH G 5 .   ? 54.64400 8.27500   -14.45800 1.000 25.04935  ? 491 HOH L O    1 
HETATM 6811 O O    . HOH G 5 .   ? 59.36300 12.68400  -9.57300  1.000 20.87856  ? 492 HOH L O    1 
HETATM 6812 O O    . HOH G 5 .   ? 32.79500 -10.11500 26.99500  1.000 23.72928  ? 493 HOH L O    1 
HETATM 6813 O O    . HOH G 5 .   ? 43.00700 0.65200   -6.28900  1.000 33.14096  ? 494 HOH L O    1 
HETATM 6814 O O    . HOH G 5 .   ? 55.88600 11.97100  20.89200  1.000 36.73954  ? 495 HOH L O    1 
HETATM 6815 O O    . HOH G 5 .   ? 38.83700 12.28500  28.58000  1.000 32.54857  ? 496 HOH L O    1 
HETATM 6816 O O    . HOH G 5 .   ? 63.95300 3.77100   -2.34500  1.000 30.32146  ? 497 HOH L O    1 
HETATM 6817 O O    . HOH G 5 .   ? 48.25500 12.24100  -4.56200  1.000 28.98984  ? 498 HOH L O    1 
HETATM 6818 O O    . HOH G 5 .   ? 44.24300 2.01500   -14.11500 1.000 32.26873  ? 499 HOH L O    1 
HETATM 6819 O O    . HOH G 5 .   ? 55.44500 1.56000   18.02600  1.000 32.53830  ? 500 HOH L O    1 
HETATM 6820 O O    . HOH G 5 .   ? 67.17400 -4.55400  -12.04000 1.000 40.18963  ? 501 HOH L O    1 
HETATM 6821 O O    . HOH G 5 .   ? 45.41300 11.36400  12.60200  1.000 33.21880  ? 502 HOH L O    1 
HETATM 6822 O O    . HOH G 5 .   ? 50.06200 -1.53500  -21.23700 1.000 35.31965  ? 503 HOH L O    1 
HETATM 6823 O O    . HOH G 5 .   ? 63.03900 6.37400   -3.04400  1.000 27.17953  ? 504 HOH L O    1 
HETATM 6824 O O    . HOH G 5 .   ? 64.95500 -3.64300  -9.05800  1.000 33.92026  ? 505 HOH L O    1 
HETATM 6825 O O    . HOH G 5 .   ? 43.54300 17.93700  30.34900  1.000 34.27824  ? 506 HOH L O    1 
HETATM 6826 O O    . HOH G 5 .   ? 52.94900 -11.12700 -17.41700 1.000 30.84936  ? 507 HOH L O    1 
HETATM 6827 O O    . HOH G 5 .   ? 35.28400 1.27300   45.54900  1.000 33.71894  ? 508 HOH L O    1 
HETATM 6828 O O    . HOH G 5 .   ? 66.42500 -10.88400 -5.06800  1.000 35.18943  ? 509 HOH L O    1 
HETATM 6829 O O    . HOH G 5 .   ? 43.30200 -3.42000  -5.95700  1.000 31.81060  ? 510 HOH L O    1 
HETATM 6830 O O    . HOH G 5 .   ? 45.87900 -4.23500  -6.62600  1.000 27.12976  ? 511 HOH L O    1 
HETATM 6831 O O    . HOH G 5 .   ? 46.38600 4.42200   14.81400  1.000 32.63900  ? 512 HOH L O    1 
HETATM 6832 O O    . HOH G 5 .   ? 71.69100 1.67900   -13.88100 1.000 48.42963  ? 513 HOH L O    1 
HETATM 6833 O O    . HOH G 5 .   ? 53.96000 14.91800  1.09600   1.000 28.74041  ? 514 HOH L O    1 
HETATM 6834 O O    . HOH G 5 .   ? 43.58200 12.59500  9.75900   1.000 42.20806  ? 515 HOH L O    1 
HETATM 6835 O O    . HOH G 5 .   ? 50.68600 -8.60900  -23.11400 1.000 39.64872  ? 516 HOH L O    1 
HETATM 6836 O O    . HOH G 5 .   ? 29.097   -0.580    23.589    1.000 33.15893  ? 517 HOH L O    1 
HETATM 6837 O O    . HOH G 5 .   ? 44.31300 0.61000   5.20800   1.000 38.94081  ? 518 HOH L O    1 
HETATM 6838 O O    . HOH G 5 .   ? 43.04600 0.68300   2.48000   1.000 42.92897  ? 519 HOH L O    1 
HETATM 6839 O O    . HOH G 5 .   ? 26.83200 4.75700   29.44500  1.000 33.81997  ? 520 HOH L O    1 
HETATM 6840 O O    . HOH G 5 .   ? 64.12100 9.13200   6.51100   1.000 33.06932  ? 521 HOH L O    1 
HETATM 6841 O O    . HOH G 5 .   ? 44.10800 2.88600   4.10500   1.000 38.86039  ? 522 HOH L O    1 
HETATM 6842 O O    . HOH G 5 .   ? 28.35800 -13.81400 29.98400  1.000 34.02975  ? 523 HOH L O    1 
HETATM 6843 O O    . HOH G 5 .   ? 44.49200 15.59400  12.97500  1.000 38.52008  ? 524 HOH L O    1 
HETATM 6844 O O    . HOH G 5 .   ? 53.36500 15.32300  20.82100  1.000 33.35909  ? 525 HOH L O    1 
HETATM 6845 O O    . HOH G 5 .   ? 46.837   -5.746    -21.959   1.000 32.78055  ? 526 HOH L O    1 
HETATM 6846 O O    . HOH G 5 .   ? 47.38100 17.81300  6.96500   1.000 38.18970  ? 527 HOH L O    1 
HETATM 6847 O O    . HOH G 5 .   ? 46.56400 17.45900  12.32300  1.000 35.25939  ? 528 HOH L O    1 
HETATM 6848 O O    . HOH G 5 .   ? 52.99400 20.35500  19.95500  1.000 38.65905  ? 529 HOH L O    1 
HETATM 6849 O O    . HOH G 5 .   ? 46.17700 18.58700  9.92300   1.000 39.04956  ? 530 HOH L O    1 
HETATM 6850 O O    . HOH H 5 .   ? 34.91500 -19.81200 41.89300  1.000 35.57834  ? 101 HOH D O    1 
HETATM 6851 O O    . HOH H 5 .   ? 31.80100 -18.17800 44.77500  1.000 37.30794  ? 102 HOH D O    1 
HETATM 6852 O O    . HOH H 5 .   ? 39.21300 -12.07400 42.68600  1.000 32.10805  ? 103 HOH D O    1 
HETATM 6853 O O    . HOH H 5 .   ? 32.71100 -24.71200 40.99600  1.000 36.21776  ? 104 HOH D O    1 
HETATM 6854 O O    . HOH H 5 .   ? 36.02300 -18.67600 44.24700  1.000 42.54689  ? 105 HOH D O    1 
# 
