data_8UIG
# 
_entry.id   8UIG 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8UIG         pdb_00008uig 10.2210/pdb8uig/pdb 
WWPDB D_1000277407 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-19 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8UIG 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-10 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              hunter@salk.edu 
_pdbx_contact_author.name_first         Tony 
_pdbx_contact_author.name_last          Hunter 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7691-6993 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kalagiri, R.'    1 0000-0002-4817-3563 
'Stanfield, R.L.' 2 0000-0001-9521-9184 
'Hunter, T.'      3 0000-0002-7691-6993 
'Wilson, I.A.'    4 0000-0002-6469-2419 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
;Using phage display for rational engineering of a higher affinity humanized 3' phosphohistidine-specific antibody.
;
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2024.11.04.621849 
_citation.pdbx_database_id_PubMed   39574610 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Martyn, G.D.'     1  ?                   
primary 'Kalagiri, R.'     2  ?                   
primary 'Veggiani, G.'     3  ?                   
primary 'Stanfield, R.L.'  4  ?                   
primary 'Choudhuri, I.'    5  ?                   
primary 'Sala, M.'         6  ?                   
primary 'Meisenhelder, J.' 7  ?                   
primary 'Chen, C.'         8  ?                   
primary 'Biswas, A.'       9  ?                   
primary 'Levy, R.M.'       10 ?                   
primary 'Lyumkis, D.'      11 ?                   
primary 'Wilson, I.A.'     12 ?                   
primary 'Hunter, T.'       13 0000-0002-7691-6993 
primary 'Sidhu, S.S.'      14 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'hSC44.ck.20 Fab heavy chain' 23597.467 1   ? ? ? 'Fab heavy chain' 
2 polymer man 'hSC44.ck.20 Fab light chain' 23879.383 1   ? ? ? 'Fab light chain' 
3 polymer syn '3pHis peptide'               747.652   1   ? ? ? ?                 
4 water   nat water                         18.015    187 ? ? ? ?                 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGTGSRFAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
;EVQLVESGGGLVQPGGSLRLSCTASGFSIDSYGFSWVRQAPGKGLEHIGYLTAGGRAFYASWAKSRSTITRNTNENTVTL
KMNSLRAEDTAVYYCAKLGTGSRFAIWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNS
GALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHT
;
H ? 
2 'polypeptide(L)' no no  
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
;DIQMTQSPSSLSASVGDRVTITCRASQSVWRNKNVAWYQQKPGKAPKRLIYAIASLYSGVPSRFSGSGSGTDFTLTISSL
QPEDFATYYCVGHYGSENDAYYAFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVSWYVDNAL
QSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTQGTTSVTKSFNRGEC
;
L ? 
3 'polypeptide(L)' no yes 'AGAG(NEP)AGAG' AGAGHAGAG C ? 
# 
_pdbx_entity_nonpoly.entity_id   4 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  THR n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  SER n 
1 29  ILE n 
1 30  ASP n 
1 31  SER n 
1 32  TYR n 
1 33  GLY n 
1 34  PHE n 
1 35  SER n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  HIS n 
1 48  ILE n 
1 49  GLY n 
1 50  TYR n 
1 51  LEU n 
1 52  THR n 
1 53  ALA n 
1 54  GLY n 
1 55  GLY n 
1 56  ARG n 
1 57  ALA n 
1 58  PHE n 
1 59  TYR n 
1 60  ALA n 
1 61  SER n 
1 62  TRP n 
1 63  ALA n 
1 64  LYS n 
1 65  SER n 
1 66  ARG n 
1 67  SER n 
1 68  THR n 
1 69  ILE n 
1 70  THR n 
1 71  ARG n 
1 72  ASN n 
1 73  THR n 
1 74  ASN n 
1 75  GLU n 
1 76  ASN n 
1 77  THR n 
1 78  VAL n 
1 79  THR n 
1 80  LEU n 
1 81  LYS n 
1 82  MET n 
1 83  ASN n 
1 84  SER n 
1 85  LEU n 
1 86  ARG n 
1 87  ALA n 
1 88  GLU n 
1 89  ASP n 
1 90  THR n 
1 91  ALA n 
1 92  VAL n 
1 93  TYR n 
1 94  TYR n 
1 95  CYS n 
1 96  ALA n 
1 97  LYS n 
1 98  LEU n 
1 99  GLY n 
1 100 THR n 
1 101 GLY n 
1 102 SER n 
1 103 ARG n 
1 104 PHE n 
1 105 ALA n 
1 106 ILE n 
1 107 TRP n 
1 108 GLY n 
1 109 GLN n 
1 110 GLY n 
1 111 THR n 
1 112 LEU n 
1 113 VAL n 
1 114 THR n 
1 115 VAL n 
1 116 SER n 
1 117 SER n 
1 118 ALA n 
1 119 SER n 
1 120 THR n 
1 121 LYS n 
1 122 GLY n 
1 123 PRO n 
1 124 SER n 
1 125 VAL n 
1 126 PHE n 
1 127 PRO n 
1 128 LEU n 
1 129 ALA n 
1 130 PRO n 
1 131 SER n 
1 132 SER n 
1 133 LYS n 
1 134 SER n 
1 135 THR n 
1 136 SER n 
1 137 GLY n 
1 138 GLY n 
1 139 THR n 
1 140 ALA n 
1 141 ALA n 
1 142 LEU n 
1 143 GLY n 
1 144 CYS n 
1 145 LEU n 
1 146 VAL n 
1 147 LYS n 
1 148 ASP n 
1 149 TYR n 
1 150 PHE n 
1 151 PRO n 
1 152 GLU n 
1 153 PRO n 
1 154 VAL n 
1 155 THR n 
1 156 VAL n 
1 157 SER n 
1 158 TRP n 
1 159 ASN n 
1 160 SER n 
1 161 GLY n 
1 162 ALA n 
1 163 LEU n 
1 164 THR n 
1 165 SER n 
1 166 GLY n 
1 167 VAL n 
1 168 HIS n 
1 169 THR n 
1 170 PHE n 
1 171 PRO n 
1 172 ALA n 
1 173 VAL n 
1 174 LEU n 
1 175 GLN n 
1 176 SER n 
1 177 SER n 
1 178 GLY n 
1 179 LEU n 
1 180 TYR n 
1 181 SER n 
1 182 LEU n 
1 183 SER n 
1 184 SER n 
1 185 VAL n 
1 186 VAL n 
1 187 THR n 
1 188 VAL n 
1 189 PRO n 
1 190 SER n 
1 191 SER n 
1 192 SER n 
1 193 LEU n 
1 194 GLY n 
1 195 THR n 
1 196 GLN n 
1 197 THR n 
1 198 TYR n 
1 199 ILE n 
1 200 CYS n 
1 201 ASN n 
1 202 VAL n 
1 203 ASN n 
1 204 HIS n 
1 205 LYS n 
1 206 PRO n 
1 207 SER n 
1 208 ASN n 
1 209 THR n 
1 210 LYS n 
1 211 VAL n 
1 212 ASP n 
1 213 LYS n 
1 214 LYS n 
1 215 VAL n 
1 216 GLU n 
1 217 PRO n 
1 218 LYS n 
1 219 SER n 
1 220 CYS n 
1 221 ASP n 
1 222 LYS n 
1 223 THR n 
1 224 HIS n 
1 225 THR n 
2 1   ASP n 
2 2   ILE n 
2 3   GLN n 
2 4   MET n 
2 5   THR n 
2 6   GLN n 
2 7   SER n 
2 8   PRO n 
2 9   SER n 
2 10  SER n 
2 11  LEU n 
2 12  SER n 
2 13  ALA n 
2 14  SER n 
2 15  VAL n 
2 16  GLY n 
2 17  ASP n 
2 18  ARG n 
2 19  VAL n 
2 20  THR n 
2 21  ILE n 
2 22  THR n 
2 23  CYS n 
2 24  ARG n 
2 25  ALA n 
2 26  SER n 
2 27  GLN n 
2 28  SER n 
2 29  VAL n 
2 30  TRP n 
2 31  ARG n 
2 32  ASN n 
2 33  LYS n 
2 34  ASN n 
2 35  VAL n 
2 36  ALA n 
2 37  TRP n 
2 38  TYR n 
2 39  GLN n 
2 40  GLN n 
2 41  LYS n 
2 42  PRO n 
2 43  GLY n 
2 44  LYS n 
2 45  ALA n 
2 46  PRO n 
2 47  LYS n 
2 48  ARG n 
2 49  LEU n 
2 50  ILE n 
2 51  TYR n 
2 52  ALA n 
2 53  ILE n 
2 54  ALA n 
2 55  SER n 
2 56  LEU n 
2 57  TYR n 
2 58  SER n 
2 59  GLY n 
2 60  VAL n 
2 61  PRO n 
2 62  SER n 
2 63  ARG n 
2 64  PHE n 
2 65  SER n 
2 66  GLY n 
2 67  SER n 
2 68  GLY n 
2 69  SER n 
2 70  GLY n 
2 71  THR n 
2 72  ASP n 
2 73  PHE n 
2 74  THR n 
2 75  LEU n 
2 76  THR n 
2 77  ILE n 
2 78  SER n 
2 79  SER n 
2 80  LEU n 
2 81  GLN n 
2 82  PRO n 
2 83  GLU n 
2 84  ASP n 
2 85  PHE n 
2 86  ALA n 
2 87  THR n 
2 88  TYR n 
2 89  TYR n 
2 90  CYS n 
2 91  VAL n 
2 92  GLY n 
2 93  HIS n 
2 94  TYR n 
2 95  GLY n 
2 96  SER n 
2 97  GLU n 
2 98  ASN n 
2 99  ASP n 
2 100 ALA n 
2 101 TYR n 
2 102 TYR n 
2 103 ALA n 
2 104 PHE n 
2 105 GLY n 
2 106 GLN n 
2 107 GLY n 
2 108 THR n 
2 109 LYS n 
2 110 VAL n 
2 111 GLU n 
2 112 ILE n 
2 113 LYS n 
2 114 ARG n 
2 115 THR n 
2 116 VAL n 
2 117 ALA n 
2 118 ALA n 
2 119 PRO n 
2 120 SER n 
2 121 VAL n 
2 122 PHE n 
2 123 ILE n 
2 124 PHE n 
2 125 PRO n 
2 126 PRO n 
2 127 SER n 
2 128 ASP n 
2 129 GLU n 
2 130 GLN n 
2 131 LEU n 
2 132 LYS n 
2 133 SER n 
2 134 GLY n 
2 135 THR n 
2 136 ALA n 
2 137 SER n 
2 138 VAL n 
2 139 VAL n 
2 140 CYS n 
2 141 LEU n 
2 142 LEU n 
2 143 ASN n 
2 144 ASN n 
2 145 PHE n 
2 146 TYR n 
2 147 PRO n 
2 148 ARG n 
2 149 GLU n 
2 150 ALA n 
2 151 LYS n 
2 152 VAL n 
2 153 SER n 
2 154 TRP n 
2 155 TYR n 
2 156 VAL n 
2 157 ASP n 
2 158 ASN n 
2 159 ALA n 
2 160 LEU n 
2 161 GLN n 
2 162 SER n 
2 163 GLY n 
2 164 ASN n 
2 165 SER n 
2 166 GLN n 
2 167 GLU n 
2 168 SER n 
2 169 VAL n 
2 170 THR n 
2 171 GLU n 
2 172 GLN n 
2 173 ASP n 
2 174 SER n 
2 175 LYS n 
2 176 ASP n 
2 177 SER n 
2 178 THR n 
2 179 TYR n 
2 180 SER n 
2 181 LEU n 
2 182 SER n 
2 183 SER n 
2 184 THR n 
2 185 LEU n 
2 186 THR n 
2 187 LEU n 
2 188 SER n 
2 189 LYS n 
2 190 ALA n 
2 191 ASP n 
2 192 TYR n 
2 193 GLU n 
2 194 LYS n 
2 195 HIS n 
2 196 LYS n 
2 197 VAL n 
2 198 TYR n 
2 199 ALA n 
2 200 CYS n 
2 201 GLU n 
2 202 VAL n 
2 203 THR n 
2 204 GLN n 
2 205 GLY n 
2 206 THR n 
2 207 THR n 
2 208 SER n 
2 209 VAL n 
2 210 THR n 
2 211 LYS n 
2 212 SER n 
2 213 PHE n 
2 214 ASN n 
2 215 ARG n 
2 216 GLY n 
2 217 GLU n 
2 218 CYS n 
3 1   ALA n 
3 2   GLY n 
3 3   ALA n 
3 4   GLY n 
3 5   NEP n 
3 6   ALA n 
3 7   GLY n 
3 8   ALA n 
3 9   GLY n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 225 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 218 ? ? ? ? ? ? ? ? ? 'Oryctolagus cuniculus' 9986 ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              3 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       9 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE               ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE              ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE            ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'       ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE              ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE             ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'       ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE               ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE             ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER                 ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE            ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE               ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE            ? 'C5 H11 N O2 S'  149.211 
NEP 'L-peptide linking' n N1-PHOSPHONOHISTIDINE ? 'C6 H10 N3 O5 P' 235.134 
PHE 'L-peptide linking' y PHENYLALANINE         ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE               ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE             ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN            ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE              ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU H . n 
A 1 2   VAL 2   2   2   VAL VAL H . n 
A 1 3   GLN 3   3   3   GLN GLN H . n 
A 1 4   LEU 4   4   4   LEU LEU H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLU 6   6   6   GLU GLU H . n 
A 1 7   SER 7   7   7   SER SER H . n 
A 1 8   GLY 8   8   8   GLY GLY H . n 
A 1 9   GLY 9   9   9   GLY GLY H . n 
A 1 10  GLY 10  10  10  GLY GLY H . n 
A 1 11  LEU 11  11  11  LEU LEU H . n 
A 1 12  VAL 12  12  12  VAL VAL H . n 
A 1 13  GLN 13  13  13  GLN GLN H . n 
A 1 14  PRO 14  14  14  PRO PRO H . n 
A 1 15  GLY 15  15  15  GLY GLY H . n 
A 1 16  GLY 16  16  16  GLY GLY H . n 
A 1 17  SER 17  17  17  SER SER H . n 
A 1 18  LEU 18  18  18  LEU LEU H . n 
A 1 19  ARG 19  19  19  ARG ARG H . n 
A 1 20  LEU 20  20  20  LEU LEU H . n 
A 1 21  SER 21  21  21  SER SER H . n 
A 1 22  CYS 22  22  22  CYS CYS H . n 
A 1 23  THR 23  23  23  THR THR H . n 
A 1 24  ALA 24  24  24  ALA ALA H . n 
A 1 25  SER 25  25  25  SER SER H . n 
A 1 26  GLY 26  26  26  GLY GLY H . n 
A 1 27  PHE 27  27  27  PHE PHE H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  ILE 29  29  29  ILE ILE H . n 
A 1 30  ASP 30  30  30  ASP ASP H . n 
A 1 31  SER 31  31  31  SER SER H . n 
A 1 32  TYR 32  32  32  TYR TYR H . n 
A 1 33  GLY 33  33  33  GLY GLY H . n 
A 1 34  PHE 34  34  34  PHE PHE H . n 
A 1 35  SER 35  35  35  SER SER H . n 
A 1 36  TRP 36  36  36  TRP TRP H . n 
A 1 37  VAL 37  37  37  VAL VAL H . n 
A 1 38  ARG 38  38  38  ARG ARG H . n 
A 1 39  GLN 39  39  39  GLN GLN H . n 
A 1 40  ALA 40  40  40  ALA ALA H . n 
A 1 41  PRO 41  41  41  PRO PRO H . n 
A 1 42  GLY 42  42  42  GLY GLY H . n 
A 1 43  LYS 43  43  43  LYS LYS H . n 
A 1 44  GLY 44  44  44  GLY GLY H . n 
A 1 45  LEU 45  45  45  LEU LEU H . n 
A 1 46  GLU 46  46  46  GLU GLU H . n 
A 1 47  HIS 47  47  47  HIS HIS H . n 
A 1 48  ILE 48  48  48  ILE ILE H . n 
A 1 49  GLY 49  49  49  GLY GLY H . n 
A 1 50  TYR 50  50  50  TYR TYR H . n 
A 1 51  LEU 51  51  51  LEU LEU H . n 
A 1 52  THR 52  52  52  THR THR H . n 
A 1 53  ALA 53  53  53  ALA ALA H . n 
A 1 54  GLY 54  54  54  GLY GLY H . n 
A 1 55  GLY 55  55  55  GLY GLY H . n 
A 1 56  ARG 56  56  56  ARG ARG H . n 
A 1 57  ALA 57  57  57  ALA ALA H . n 
A 1 58  PHE 58  58  58  PHE PHE H . n 
A 1 59  TYR 59  59  59  TYR TYR H . n 
A 1 60  ALA 60  60  60  ALA ALA H . n 
A 1 61  SER 61  61  61  SER SER H . n 
A 1 62  TRP 62  62  62  TRP TRP H . n 
A 1 63  ALA 63  63  63  ALA ALA H . n 
A 1 64  LYS 64  64  64  LYS LYS H . n 
A 1 65  SER 65  65  65  SER SER H . n 
A 1 66  ARG 66  66  66  ARG ARG H . n 
A 1 67  SER 67  67  67  SER SER H . n 
A 1 68  THR 68  68  68  THR THR H . n 
A 1 69  ILE 69  69  69  ILE ILE H . n 
A 1 70  THR 70  70  70  THR THR H . n 
A 1 71  ARG 71  71  71  ARG ARG H . n 
A 1 72  ASN 72  72  72  ASN ASN H . n 
A 1 73  THR 73  73  73  THR THR H . n 
A 1 74  ASN 74  74  74  ASN ASN H . n 
A 1 75  GLU 75  75  75  GLU GLU H . n 
A 1 76  ASN 76  76  76  ASN ASN H . n 
A 1 77  THR 77  77  77  THR THR H . n 
A 1 78  VAL 78  78  78  VAL VAL H . n 
A 1 79  THR 79  79  79  THR THR H . n 
A 1 80  LEU 80  80  80  LEU LEU H . n 
A 1 81  LYS 81  81  81  LYS LYS H . n 
A 1 82  MET 82  82  82  MET MET H . n 
A 1 83  ASN 83  82  82  ASN ASN H A n 
A 1 84  SER 84  82  82  SER SER H B n 
A 1 85  LEU 85  82  82  LEU LEU H C n 
A 1 86  ARG 86  83  83  ARG ARG H . n 
A 1 87  ALA 87  84  84  ALA ALA H . n 
A 1 88  GLU 88  85  85  GLU GLU H . n 
A 1 89  ASP 89  86  86  ASP ASP H . n 
A 1 90  THR 90  87  87  THR THR H . n 
A 1 91  ALA 91  88  88  ALA ALA H . n 
A 1 92  VAL 92  89  89  VAL VAL H . n 
A 1 93  TYR 93  90  90  TYR TYR H . n 
A 1 94  TYR 94  91  91  TYR TYR H . n 
A 1 95  CYS 95  92  92  CYS CYS H . n 
A 1 96  ALA 96  93  93  ALA ALA H . n 
A 1 97  LYS 97  94  94  LYS LYS H . n 
A 1 98  LEU 98  95  95  LEU LEU H . n 
A 1 99  GLY 99  96  96  GLY GLY H . n 
A 1 100 THR 100 97  97  THR THR H . n 
A 1 101 GLY 101 98  98  GLY GLY H . n 
A 1 102 SER 102 99  99  SER SER H . n 
A 1 103 ARG 103 100 100 ARG ARG H . n 
A 1 104 PHE 104 100 100 PHE PHE H A n 
A 1 105 ALA 105 101 101 ALA ALA H . n 
A 1 106 ILE 106 102 102 ILE ILE H . n 
A 1 107 TRP 107 103 103 TRP TRP H . n 
A 1 108 GLY 108 104 104 GLY GLY H . n 
A 1 109 GLN 109 105 105 GLN GLN H . n 
A 1 110 GLY 110 106 106 GLY GLY H . n 
A 1 111 THR 111 107 107 THR THR H . n 
A 1 112 LEU 112 108 108 LEU LEU H . n 
A 1 113 VAL 113 109 109 VAL VAL H . n 
A 1 114 THR 114 110 110 THR THR H . n 
A 1 115 VAL 115 111 111 VAL VAL H . n 
A 1 116 SER 116 112 112 SER SER H . n 
A 1 117 SER 117 113 113 SER SER H . n 
A 1 118 ALA 118 114 114 ALA ALA H . n 
A 1 119 SER 119 115 115 SER SER H . n 
A 1 120 THR 120 116 116 THR THR H . n 
A 1 121 LYS 121 117 117 LYS LYS H . n 
A 1 122 GLY 122 118 118 GLY GLY H . n 
A 1 123 PRO 123 119 119 PRO PRO H . n 
A 1 124 SER 124 120 120 SER SER H . n 
A 1 125 VAL 125 121 121 VAL VAL H . n 
A 1 126 PHE 126 122 122 PHE PHE H . n 
A 1 127 PRO 127 123 123 PRO PRO H . n 
A 1 128 LEU 128 124 124 LEU LEU H . n 
A 1 129 ALA 129 125 125 ALA ALA H . n 
A 1 130 PRO 130 126 126 PRO PRO H . n 
A 1 131 SER 131 127 127 SER SER H . n 
A 1 132 SER 132 128 128 SER SER H . n 
A 1 133 LYS 133 129 129 LYS LYS H . n 
A 1 134 SER 134 130 130 SER SER H . n 
A 1 135 THR 135 131 131 THR THR H . n 
A 1 136 SER 136 132 132 SER SER H . n 
A 1 137 GLY 137 133 133 GLY GLY H . n 
A 1 138 GLY 138 134 134 GLY GLY H . n 
A 1 139 THR 139 135 135 THR THR H . n 
A 1 140 ALA 140 136 136 ALA ALA H . n 
A 1 141 ALA 141 137 137 ALA ALA H . n 
A 1 142 LEU 142 138 138 LEU LEU H . n 
A 1 143 GLY 143 139 139 GLY GLY H . n 
A 1 144 CYS 144 140 140 CYS CYS H . n 
A 1 145 LEU 145 141 141 LEU LEU H . n 
A 1 146 VAL 146 142 142 VAL VAL H . n 
A 1 147 LYS 147 143 143 LYS LYS H . n 
A 1 148 ASP 148 144 144 ASP ASP H . n 
A 1 149 TYR 149 145 145 TYR TYR H . n 
A 1 150 PHE 150 146 146 PHE PHE H . n 
A 1 151 PRO 151 147 147 PRO PRO H . n 
A 1 152 GLU 152 148 148 GLU GLU H . n 
A 1 153 PRO 153 149 149 PRO PRO H . n 
A 1 154 VAL 154 150 150 VAL VAL H . n 
A 1 155 THR 155 151 151 THR THR H . n 
A 1 156 VAL 156 152 152 VAL VAL H . n 
A 1 157 SER 157 153 153 SER SER H . n 
A 1 158 TRP 158 154 154 TRP TRP H . n 
A 1 159 ASN 159 155 155 ASN ASN H . n 
A 1 160 SER 160 156 156 SER SER H . n 
A 1 161 GLY 161 157 157 GLY GLY H . n 
A 1 162 ALA 162 158 158 ALA ALA H . n 
A 1 163 LEU 163 159 159 LEU LEU H . n 
A 1 164 THR 164 160 160 THR THR H . n 
A 1 165 SER 165 161 161 SER SER H . n 
A 1 166 GLY 166 162 162 GLY GLY H . n 
A 1 167 VAL 167 163 163 VAL VAL H . n 
A 1 168 HIS 168 164 164 HIS HIS H . n 
A 1 169 THR 169 165 165 THR THR H . n 
A 1 170 PHE 170 166 166 PHE PHE H . n 
A 1 171 PRO 171 167 167 PRO PRO H . n 
A 1 172 ALA 172 168 168 ALA ALA H . n 
A 1 173 VAL 173 169 169 VAL VAL H . n 
A 1 174 LEU 174 170 170 LEU LEU H . n 
A 1 175 GLN 175 171 171 GLN GLN H . n 
A 1 176 SER 176 172 172 SER SER H . n 
A 1 177 SER 177 173 173 SER SER H . n 
A 1 178 GLY 178 174 174 GLY GLY H . n 
A 1 179 LEU 179 175 175 LEU LEU H . n 
A 1 180 TYR 180 176 176 TYR TYR H . n 
A 1 181 SER 181 177 177 SER SER H . n 
A 1 182 LEU 182 178 178 LEU LEU H . n 
A 1 183 SER 183 179 179 SER SER H . n 
A 1 184 SER 184 180 180 SER SER H . n 
A 1 185 VAL 185 181 181 VAL VAL H . n 
A 1 186 VAL 186 182 182 VAL VAL H . n 
A 1 187 THR 187 183 183 THR THR H . n 
A 1 188 VAL 188 184 184 VAL VAL H . n 
A 1 189 PRO 189 185 185 PRO PRO H . n 
A 1 190 SER 190 186 186 SER SER H . n 
A 1 191 SER 191 187 187 SER SER H . n 
A 1 192 SER 192 188 188 SER SER H . n 
A 1 193 LEU 193 189 189 LEU LEU H . n 
A 1 194 GLY 194 190 190 GLY GLY H . n 
A 1 195 THR 195 191 191 THR THR H . n 
A 1 196 GLN 196 192 192 GLN GLN H . n 
A 1 197 THR 197 193 193 THR THR H . n 
A 1 198 TYR 198 194 194 TYR TYR H . n 
A 1 199 ILE 199 195 195 ILE ILE H . n 
A 1 200 CYS 200 196 196 CYS CYS H . n 
A 1 201 ASN 201 197 197 ASN ASN H . n 
A 1 202 VAL 202 198 198 VAL VAL H . n 
A 1 203 ASN 203 199 199 ASN ASN H . n 
A 1 204 HIS 204 200 200 HIS HIS H . n 
A 1 205 LYS 205 201 201 LYS LYS H . n 
A 1 206 PRO 206 202 202 PRO PRO H . n 
A 1 207 SER 207 203 203 SER SER H . n 
A 1 208 ASN 208 204 204 ASN ASN H . n 
A 1 209 THR 209 205 205 THR THR H . n 
A 1 210 LYS 210 206 206 LYS LYS H . n 
A 1 211 VAL 211 207 207 VAL VAL H . n 
A 1 212 ASP 212 208 208 ASP ASP H . n 
A 1 213 LYS 213 209 209 LYS LYS H . n 
A 1 214 LYS 214 210 210 LYS LYS H . n 
A 1 215 VAL 215 211 211 VAL VAL H . n 
A 1 216 GLU 216 212 212 GLU GLU H . n 
A 1 217 PRO 217 213 213 PRO PRO H . n 
A 1 218 LYS 218 214 214 LYS LYS H . n 
A 1 219 SER 219 215 ?   ?   ?   H . n 
A 1 220 CYS 220 216 ?   ?   ?   H . n 
A 1 221 ASP 221 217 ?   ?   ?   H . n 
A 1 222 LYS 222 218 ?   ?   ?   H . n 
A 1 223 THR 223 219 ?   ?   ?   H . n 
A 1 224 HIS 224 220 ?   ?   ?   H . n 
A 1 225 THR 225 221 ?   ?   ?   H . n 
B 2 1   ASP 1   1   1   ASP ASP L . n 
B 2 2   ILE 2   2   2   ILE ILE L . n 
B 2 3   GLN 3   3   3   GLN GLN L . n 
B 2 4   MET 4   4   4   MET MET L . n 
B 2 5   THR 5   5   5   THR THR L . n 
B 2 6   GLN 6   6   6   GLN GLN L . n 
B 2 7   SER 7   7   7   SER SER L . n 
B 2 8   PRO 8   8   8   PRO PRO L . n 
B 2 9   SER 9   9   9   SER SER L . n 
B 2 10  SER 10  10  10  SER SER L . n 
B 2 11  LEU 11  11  11  LEU LEU L . n 
B 2 12  SER 12  12  12  SER SER L . n 
B 2 13  ALA 13  13  13  ALA ALA L . n 
B 2 14  SER 14  14  14  SER SER L . n 
B 2 15  VAL 15  15  15  VAL VAL L . n 
B 2 16  GLY 16  16  16  GLY GLY L . n 
B 2 17  ASP 17  17  17  ASP ASP L . n 
B 2 18  ARG 18  18  18  ARG ARG L . n 
B 2 19  VAL 19  19  19  VAL VAL L . n 
B 2 20  THR 20  20  20  THR THR L . n 
B 2 21  ILE 21  21  21  ILE ILE L . n 
B 2 22  THR 22  22  22  THR THR L . n 
B 2 23  CYS 23  23  23  CYS CYS L . n 
B 2 24  ARG 24  24  24  ARG ARG L . n 
B 2 25  ALA 25  25  25  ALA ALA L . n 
B 2 26  SER 26  26  26  SER SER L . n 
B 2 27  GLN 27  27  27  GLN GLN L . n 
B 2 28  SER 28  27  27  SER SER L A n 
B 2 29  VAL 29  27  27  VAL VAL L B n 
B 2 30  TRP 30  28  28  TRP TRP L . n 
B 2 31  ARG 31  29  29  ARG ARG L . n 
B 2 32  ASN 32  30  30  ASN ASN L . n 
B 2 33  LYS 33  31  31  LYS LYS L . n 
B 2 34  ASN 34  32  32  ASN ASN L . n 
B 2 35  VAL 35  33  33  VAL VAL L . n 
B 2 36  ALA 36  34  34  ALA ALA L . n 
B 2 37  TRP 37  35  35  TRP TRP L . n 
B 2 38  TYR 38  36  36  TYR TYR L . n 
B 2 39  GLN 39  37  37  GLN GLN L . n 
B 2 40  GLN 40  38  38  GLN GLN L . n 
B 2 41  LYS 41  39  39  LYS LYS L . n 
B 2 42  PRO 42  40  40  PRO PRO L . n 
B 2 43  GLY 43  41  41  GLY GLY L . n 
B 2 44  LYS 44  42  42  LYS LYS L . n 
B 2 45  ALA 45  43  43  ALA ALA L . n 
B 2 46  PRO 46  44  44  PRO PRO L . n 
B 2 47  LYS 47  45  45  LYS LYS L . n 
B 2 48  ARG 48  46  46  ARG ARG L . n 
B 2 49  LEU 49  47  47  LEU LEU L . n 
B 2 50  ILE 50  48  48  ILE ILE L . n 
B 2 51  TYR 51  49  49  TYR TYR L . n 
B 2 52  ALA 52  50  50  ALA ALA L . n 
B 2 53  ILE 53  51  51  ILE ILE L . n 
B 2 54  ALA 54  52  52  ALA ALA L . n 
B 2 55  SER 55  53  53  SER SER L . n 
B 2 56  LEU 56  54  54  LEU LEU L . n 
B 2 57  TYR 57  55  55  TYR TYR L . n 
B 2 58  SER 58  56  56  SER SER L . n 
B 2 59  GLY 59  57  57  GLY GLY L . n 
B 2 60  VAL 60  58  58  VAL VAL L . n 
B 2 61  PRO 61  59  59  PRO PRO L . n 
B 2 62  SER 62  60  60  SER SER L . n 
B 2 63  ARG 63  61  61  ARG ARG L . n 
B 2 64  PHE 64  62  62  PHE PHE L . n 
B 2 65  SER 65  63  63  SER SER L . n 
B 2 66  GLY 66  64  64  GLY GLY L . n 
B 2 67  SER 67  65  65  SER SER L . n 
B 2 68  GLY 68  66  66  GLY GLY L . n 
B 2 69  SER 69  67  67  SER SER L . n 
B 2 70  GLY 70  68  68  GLY GLY L . n 
B 2 71  THR 71  69  69  THR THR L . n 
B 2 72  ASP 72  70  70  ASP ASP L . n 
B 2 73  PHE 73  71  71  PHE PHE L . n 
B 2 74  THR 74  72  72  THR THR L . n 
B 2 75  LEU 75  73  73  LEU LEU L . n 
B 2 76  THR 76  74  74  THR THR L . n 
B 2 77  ILE 77  75  75  ILE ILE L . n 
B 2 78  SER 78  76  76  SER SER L . n 
B 2 79  SER 79  77  77  SER SER L . n 
B 2 80  LEU 80  78  78  LEU LEU L . n 
B 2 81  GLN 81  79  79  GLN GLN L . n 
B 2 82  PRO 82  80  80  PRO PRO L . n 
B 2 83  GLU 83  81  81  GLU GLU L . n 
B 2 84  ASP 84  82  82  ASP ASP L . n 
B 2 85  PHE 85  83  83  PHE PHE L . n 
B 2 86  ALA 86  84  84  ALA ALA L . n 
B 2 87  THR 87  85  85  THR THR L . n 
B 2 88  TYR 88  86  86  TYR TYR L . n 
B 2 89  TYR 89  87  87  TYR TYR L . n 
B 2 90  CYS 90  88  88  CYS CYS L . n 
B 2 91  VAL 91  89  89  VAL VAL L . n 
B 2 92  GLY 92  90  90  GLY GLY L . n 
B 2 93  HIS 93  91  91  HIS HIS L . n 
B 2 94  TYR 94  92  92  TYR TYR L . n 
B 2 95  GLY 95  93  93  GLY GLY L . n 
B 2 96  SER 96  94  94  SER SER L . n 
B 2 97  GLU 97  95  95  GLU GLU L . n 
B 2 98  ASN 98  95  95  ASN ASN L A n 
B 2 99  ASP 99  95  95  ASP ASP L B n 
B 2 100 ALA 100 95  95  ALA ALA L C n 
B 2 101 TYR 101 95  95  TYR TYR L D n 
B 2 102 TYR 102 96  96  TYR TYR L . n 
B 2 103 ALA 103 97  97  ALA ALA L . n 
B 2 104 PHE 104 98  98  PHE PHE L . n 
B 2 105 GLY 105 99  99  GLY GLY L . n 
B 2 106 GLN 106 100 100 GLN GLN L . n 
B 2 107 GLY 107 101 101 GLY GLY L . n 
B 2 108 THR 108 102 102 THR THR L . n 
B 2 109 LYS 109 103 103 LYS LYS L . n 
B 2 110 VAL 110 104 104 VAL VAL L . n 
B 2 111 GLU 111 105 105 GLU GLU L . n 
B 2 112 ILE 112 106 106 ILE ILE L . n 
B 2 113 LYS 113 107 107 LYS LYS L . n 
B 2 114 ARG 114 108 108 ARG ARG L . n 
B 2 115 THR 115 109 109 THR THR L . n 
B 2 116 VAL 116 110 110 VAL VAL L . n 
B 2 117 ALA 117 111 111 ALA ALA L . n 
B 2 118 ALA 118 112 112 ALA ALA L . n 
B 2 119 PRO 119 113 113 PRO PRO L . n 
B 2 120 SER 120 114 114 SER SER L . n 
B 2 121 VAL 121 115 115 VAL VAL L . n 
B 2 122 PHE 122 116 116 PHE PHE L . n 
B 2 123 ILE 123 117 117 ILE ILE L . n 
B 2 124 PHE 124 118 118 PHE PHE L . n 
B 2 125 PRO 125 119 119 PRO PRO L . n 
B 2 126 PRO 126 120 120 PRO PRO L . n 
B 2 127 SER 127 121 121 SER SER L . n 
B 2 128 ASP 128 122 122 ASP ASP L . n 
B 2 129 GLU 129 123 123 GLU GLU L . n 
B 2 130 GLN 130 124 124 GLN GLN L . n 
B 2 131 LEU 131 125 125 LEU LEU L . n 
B 2 132 LYS 132 126 126 LYS LYS L . n 
B 2 133 SER 133 127 127 SER SER L . n 
B 2 134 GLY 134 128 128 GLY GLY L . n 
B 2 135 THR 135 129 129 THR THR L . n 
B 2 136 ALA 136 130 130 ALA ALA L . n 
B 2 137 SER 137 131 131 SER SER L . n 
B 2 138 VAL 138 132 132 VAL VAL L . n 
B 2 139 VAL 139 133 133 VAL VAL L . n 
B 2 140 CYS 140 134 134 CYS CYS L . n 
B 2 141 LEU 141 135 135 LEU LEU L . n 
B 2 142 LEU 142 136 136 LEU LEU L . n 
B 2 143 ASN 143 137 137 ASN ASN L . n 
B 2 144 ASN 144 138 138 ASN ASN L . n 
B 2 145 PHE 145 139 139 PHE PHE L . n 
B 2 146 TYR 146 140 140 TYR TYR L . n 
B 2 147 PRO 147 141 141 PRO PRO L . n 
B 2 148 ARG 148 142 142 ARG ARG L . n 
B 2 149 GLU 149 143 143 GLU GLU L . n 
B 2 150 ALA 150 144 144 ALA ALA L . n 
B 2 151 LYS 151 145 145 LYS LYS L . n 
B 2 152 VAL 152 146 146 VAL VAL L . n 
B 2 153 SER 153 147 147 SER SER L . n 
B 2 154 TRP 154 148 148 TRP TRP L . n 
B 2 155 TYR 155 149 149 TYR TYR L . n 
B 2 156 VAL 156 150 150 VAL VAL L . n 
B 2 157 ASP 157 151 151 ASP ASP L . n 
B 2 158 ASN 158 152 152 ASN ASN L . n 
B 2 159 ALA 159 153 153 ALA ALA L . n 
B 2 160 LEU 160 154 154 LEU LEU L . n 
B 2 161 GLN 161 155 155 GLN GLN L . n 
B 2 162 SER 162 156 156 SER SER L . n 
B 2 163 GLY 163 157 157 GLY GLY L . n 
B 2 164 ASN 164 158 158 ASN ASN L . n 
B 2 165 SER 165 159 159 SER SER L . n 
B 2 166 GLN 166 160 160 GLN GLN L . n 
B 2 167 GLU 167 161 161 GLU GLU L . n 
B 2 168 SER 168 162 162 SER SER L . n 
B 2 169 VAL 169 163 163 VAL VAL L . n 
B 2 170 THR 170 164 164 THR THR L . n 
B 2 171 GLU 171 165 165 GLU GLU L . n 
B 2 172 GLN 172 166 166 GLN GLN L . n 
B 2 173 ASP 173 167 167 ASP ASP L . n 
B 2 174 SER 174 168 168 SER SER L . n 
B 2 175 LYS 175 169 169 LYS LYS L . n 
B 2 176 ASP 176 170 170 ASP ASP L . n 
B 2 177 SER 177 171 171 SER SER L . n 
B 2 178 THR 178 172 172 THR THR L . n 
B 2 179 TYR 179 173 173 TYR TYR L . n 
B 2 180 SER 180 174 174 SER SER L . n 
B 2 181 LEU 181 175 175 LEU LEU L . n 
B 2 182 SER 182 176 176 SER SER L . n 
B 2 183 SER 183 177 177 SER SER L . n 
B 2 184 THR 184 178 178 THR THR L . n 
B 2 185 LEU 185 179 179 LEU LEU L . n 
B 2 186 THR 186 180 180 THR THR L . n 
B 2 187 LEU 187 181 181 LEU LEU L . n 
B 2 188 SER 188 182 182 SER SER L . n 
B 2 189 LYS 189 183 183 LYS LYS L . n 
B 2 190 ALA 190 184 184 ALA ALA L . n 
B 2 191 ASP 191 185 185 ASP ASP L . n 
B 2 192 TYR 192 186 186 TYR TYR L . n 
B 2 193 GLU 193 187 187 GLU GLU L . n 
B 2 194 LYS 194 188 188 LYS LYS L . n 
B 2 195 HIS 195 189 189 HIS HIS L . n 
B 2 196 LYS 196 190 190 LYS LYS L . n 
B 2 197 VAL 197 191 191 VAL VAL L . n 
B 2 198 TYR 198 192 192 TYR TYR L . n 
B 2 199 ALA 199 193 193 ALA ALA L . n 
B 2 200 CYS 200 194 194 CYS CYS L . n 
B 2 201 GLU 201 195 195 GLU GLU L . n 
B 2 202 VAL 202 196 196 VAL VAL L . n 
B 2 203 THR 203 197 197 THR THR L . n 
B 2 204 GLN 204 198 198 GLN GLN L . n 
B 2 205 GLY 205 199 199 GLY GLY L . n 
B 2 206 THR 206 200 200 THR THR L . n 
B 2 207 THR 207 201 201 THR THR L . n 
B 2 208 SER 208 202 202 SER SER L . n 
B 2 209 VAL 209 203 203 VAL VAL L . n 
B 2 210 THR 210 204 204 THR THR L . n 
B 2 211 LYS 211 205 205 LYS LYS L . n 
B 2 212 SER 212 206 206 SER SER L . n 
B 2 213 PHE 213 207 207 PHE PHE L . n 
B 2 214 ASN 214 208 208 ASN ASN L . n 
B 2 215 ARG 215 209 209 ARG ARG L . n 
B 2 216 GLY 216 210 210 GLY GLY L . n 
B 2 217 GLU 217 211 211 GLU GLU L . n 
B 2 218 CYS 218 212 212 CYS CYS L . n 
C 3 1   ALA 1   1   ?   ?   ?   C . n 
C 3 2   GLY 2   2   ?   ?   ?   C . n 
C 3 3   ALA 3   3   3   ALA ALA C . n 
C 3 4   GLY 4   4   4   GLY GLY C . n 
C 3 5   NEP 5   5   5   NEP NEP C . n 
C 3 6   ALA 6   6   6   ALA ALA C . n 
C 3 7   GLY 7   7   7   GLY GLY C . n 
C 3 8   ALA 8   8   8   ALA ALA C . n 
C 3 9   GLY 9   9   9   GLY GLY C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NEP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NEP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
D 4 HOH 1   301 63  HOH HOH H . 
D 4 HOH 2   302 28  HOH HOH H . 
D 4 HOH 3   303 165 HOH HOH H . 
D 4 HOH 4   304 22  HOH HOH H . 
D 4 HOH 5   305 168 HOH HOH H . 
D 4 HOH 6   306 196 HOH HOH H . 
D 4 HOH 7   307 147 HOH HOH H . 
D 4 HOH 8   308 41  HOH HOH H . 
D 4 HOH 9   309 23  HOH HOH H . 
D 4 HOH 10  310 48  HOH HOH H . 
D 4 HOH 11  311 81  HOH HOH H . 
D 4 HOH 12  312 118 HOH HOH H . 
D 4 HOH 13  313 120 HOH HOH H . 
D 4 HOH 14  314 124 HOH HOH H . 
D 4 HOH 15  315 16  HOH HOH H . 
D 4 HOH 16  316 2   HOH HOH H . 
D 4 HOH 17  317 100 HOH HOH H . 
D 4 HOH 18  318 80  HOH HOH H . 
D 4 HOH 19  319 30  HOH HOH H . 
D 4 HOH 20  320 76  HOH HOH H . 
D 4 HOH 21  321 31  HOH HOH H . 
D 4 HOH 22  322 155 HOH HOH H . 
D 4 HOH 23  323 162 HOH HOH H . 
D 4 HOH 24  324 43  HOH HOH H . 
D 4 HOH 25  325 191 HOH HOH H . 
D 4 HOH 26  326 87  HOH HOH H . 
D 4 HOH 27  327 58  HOH HOH H . 
D 4 HOH 28  328 39  HOH HOH H . 
D 4 HOH 29  329 185 HOH HOH H . 
D 4 HOH 30  330 47  HOH HOH H . 
D 4 HOH 31  331 167 HOH HOH H . 
D 4 HOH 32  332 73  HOH HOH H . 
D 4 HOH 33  333 130 HOH HOH H . 
D 4 HOH 34  334 38  HOH HOH H . 
D 4 HOH 35  335 133 HOH HOH H . 
D 4 HOH 36  336 82  HOH HOH H . 
D 4 HOH 37  337 197 HOH HOH H . 
D 4 HOH 38  338 160 HOH HOH H . 
D 4 HOH 39  339 10  HOH HOH H . 
D 4 HOH 40  340 25  HOH HOH H . 
D 4 HOH 41  341 132 HOH HOH H . 
D 4 HOH 42  342 3   HOH HOH H . 
D 4 HOH 43  343 79  HOH HOH H . 
D 4 HOH 44  344 4   HOH HOH H . 
D 4 HOH 45  345 158 HOH HOH H . 
D 4 HOH 46  346 78  HOH HOH H . 
D 4 HOH 47  347 129 HOH HOH H . 
D 4 HOH 48  348 29  HOH HOH H . 
D 4 HOH 49  349 105 HOH HOH H . 
D 4 HOH 50  350 126 HOH HOH H . 
D 4 HOH 51  351 151 HOH HOH H . 
D 4 HOH 52  352 98  HOH HOH H . 
D 4 HOH 53  353 86  HOH HOH H . 
D 4 HOH 54  354 1   HOH HOH H . 
D 4 HOH 55  355 61  HOH HOH H . 
D 4 HOH 56  356 159 HOH HOH H . 
D 4 HOH 57  357 69  HOH HOH H . 
D 4 HOH 58  358 99  HOH HOH H . 
D 4 HOH 59  359 115 HOH HOH H . 
D 4 HOH 60  360 106 HOH HOH H . 
D 4 HOH 61  361 62  HOH HOH H . 
D 4 HOH 62  362 173 HOH HOH H . 
D 4 HOH 63  363 138 HOH HOH H . 
D 4 HOH 64  364 40  HOH HOH H . 
D 4 HOH 65  365 71  HOH HOH H . 
D 4 HOH 66  366 46  HOH HOH H . 
D 4 HOH 67  367 54  HOH HOH H . 
D 4 HOH 68  368 35  HOH HOH H . 
D 4 HOH 69  369 7   HOH HOH H . 
D 4 HOH 70  370 57  HOH HOH H . 
D 4 HOH 71  371 11  HOH HOH H . 
D 4 HOH 72  372 95  HOH HOH H . 
D 4 HOH 73  373 189 HOH HOH H . 
D 4 HOH 74  374 171 HOH HOH H . 
D 4 HOH 75  375 55  HOH HOH H . 
D 4 HOH 76  376 182 HOH HOH H . 
D 4 HOH 77  377 45  HOH HOH H . 
D 4 HOH 78  378 154 HOH HOH H . 
D 4 HOH 79  379 169 HOH HOH H . 
D 4 HOH 80  380 26  HOH HOH H . 
D 4 HOH 81  381 107 HOH HOH H . 
E 4 HOH 1   301 77  HOH HOH L . 
E 4 HOH 2   302 19  HOH HOH L . 
E 4 HOH 3   303 88  HOH HOH L . 
E 4 HOH 4   304 111 HOH HOH L . 
E 4 HOH 5   305 146 HOH HOH L . 
E 4 HOH 6   306 32  HOH HOH L . 
E 4 HOH 7   307 192 HOH HOH L . 
E 4 HOH 8   308 178 HOH HOH L . 
E 4 HOH 9   309 122 HOH HOH L . 
E 4 HOH 10  310 174 HOH HOH L . 
E 4 HOH 11  311 145 HOH HOH L . 
E 4 HOH 12  312 24  HOH HOH L . 
E 4 HOH 13  313 128 HOH HOH L . 
E 4 HOH 14  314 179 HOH HOH L . 
E 4 HOH 15  315 176 HOH HOH L . 
E 4 HOH 16  316 92  HOH HOH L . 
E 4 HOH 17  317 123 HOH HOH L . 
E 4 HOH 18  318 103 HOH HOH L . 
E 4 HOH 19  319 51  HOH HOH L . 
E 4 HOH 20  320 96  HOH HOH L . 
E 4 HOH 21  321 142 HOH HOH L . 
E 4 HOH 22  322 136 HOH HOH L . 
E 4 HOH 23  323 137 HOH HOH L . 
E 4 HOH 24  324 194 HOH HOH L . 
E 4 HOH 25  325 187 HOH HOH L . 
E 4 HOH 26  326 83  HOH HOH L . 
E 4 HOH 27  327 42  HOH HOH L . 
E 4 HOH 28  328 53  HOH HOH L . 
E 4 HOH 29  329 116 HOH HOH L . 
E 4 HOH 30  330 9   HOH HOH L . 
E 4 HOH 31  331 64  HOH HOH L . 
E 4 HOH 32  332 93  HOH HOH L . 
E 4 HOH 33  333 20  HOH HOH L . 
E 4 HOH 34  334 193 HOH HOH L . 
E 4 HOH 35  335 13  HOH HOH L . 
E 4 HOH 36  336 33  HOH HOH L . 
E 4 HOH 37  337 121 HOH HOH L . 
E 4 HOH 38  338 152 HOH HOH L . 
E 4 HOH 39  339 140 HOH HOH L . 
E 4 HOH 40  340 97  HOH HOH L . 
E 4 HOH 41  341 114 HOH HOH L . 
E 4 HOH 42  342 180 HOH HOH L . 
E 4 HOH 43  343 36  HOH HOH L . 
E 4 HOH 44  344 75  HOH HOH L . 
E 4 HOH 45  345 17  HOH HOH L . 
E 4 HOH 46  346 21  HOH HOH L . 
E 4 HOH 47  347 8   HOH HOH L . 
E 4 HOH 48  348 68  HOH HOH L . 
E 4 HOH 49  349 181 HOH HOH L . 
E 4 HOH 50  350 139 HOH HOH L . 
E 4 HOH 51  351 85  HOH HOH L . 
E 4 HOH 52  352 149 HOH HOH L . 
E 4 HOH 53  353 150 HOH HOH L . 
E 4 HOH 54  354 14  HOH HOH L . 
E 4 HOH 55  355 141 HOH HOH L . 
E 4 HOH 56  356 104 HOH HOH L . 
E 4 HOH 57  357 70  HOH HOH L . 
E 4 HOH 58  358 90  HOH HOH L . 
E 4 HOH 59  359 6   HOH HOH L . 
E 4 HOH 60  360 49  HOH HOH L . 
E 4 HOH 61  361 60  HOH HOH L . 
E 4 HOH 62  362 110 HOH HOH L . 
E 4 HOH 63  363 112 HOH HOH L . 
E 4 HOH 64  364 15  HOH HOH L . 
E 4 HOH 65  365 156 HOH HOH L . 
E 4 HOH 66  366 113 HOH HOH L . 
E 4 HOH 67  367 134 HOH HOH L . 
E 4 HOH 68  368 59  HOH HOH L . 
E 4 HOH 69  369 131 HOH HOH L . 
E 4 HOH 70  370 148 HOH HOH L . 
E 4 HOH 71  371 27  HOH HOH L . 
E 4 HOH 72  372 56  HOH HOH L . 
E 4 HOH 73  373 94  HOH HOH L . 
E 4 HOH 74  374 18  HOH HOH L . 
E 4 HOH 75  375 52  HOH HOH L . 
E 4 HOH 76  376 37  HOH HOH L . 
E 4 HOH 77  377 67  HOH HOH L . 
E 4 HOH 78  378 72  HOH HOH L . 
E 4 HOH 79  379 66  HOH HOH L . 
E 4 HOH 80  380 161 HOH HOH L . 
E 4 HOH 81  381 5   HOH HOH L . 
E 4 HOH 82  382 84  HOH HOH L . 
E 4 HOH 83  383 12  HOH HOH L . 
E 4 HOH 84  384 144 HOH HOH L . 
E 4 HOH 85  385 153 HOH HOH L . 
E 4 HOH 86  386 108 HOH HOH L . 
E 4 HOH 87  387 127 HOH HOH L . 
E 4 HOH 88  388 186 HOH HOH L . 
E 4 HOH 89  389 89  HOH HOH L . 
E 4 HOH 90  390 195 HOH HOH L . 
E 4 HOH 91  391 65  HOH HOH L . 
E 4 HOH 92  392 135 HOH HOH L . 
E 4 HOH 93  393 102 HOH HOH L . 
E 4 HOH 94  394 166 HOH HOH L . 
E 4 HOH 95  395 44  HOH HOH L . 
E 4 HOH 96  396 175 HOH HOH L . 
E 4 HOH 97  397 170 HOH HOH L . 
E 4 HOH 98  398 143 HOH HOH L . 
E 4 HOH 99  399 163 HOH HOH L . 
E 4 HOH 100 400 74  HOH HOH L . 
E 4 HOH 101 401 117 HOH HOH L . 
F 4 HOH 1   101 177 HOH HOH C . 
F 4 HOH 2   102 184 HOH HOH C . 
F 4 HOH 3   103 34  HOH HOH C . 
F 4 HOH 4   104 50  HOH HOH C . 
F 4 HOH 5   105 119 HOH HOH C . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   98.207 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8UIG 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     44.111 
_cell.length_a_esd                 ? 
_cell.length_b                     72.605 
_cell.length_b_esd                 ? 
_cell.length_c                     70.325 
_cell.length_c_esd                 ? 
_cell.volume                       222921.802 
_cell.volume_esd                   ? 
_cell.Z_PDB                        2 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8UIG 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8UIG 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.31 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          46.78 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.2M tri-potassium citrate, 20% PEG 3350' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER2 XE 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2022-06-25 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97946 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97946 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          20.88 
_reflns.entry_id                                       8UIG 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.90 
_reflns.d_resolution_low                               34.82 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     33299 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     0.0 
_reflns.observed_criterion_sigma_I                     -3.0 
_reflns.percent_possible_obs                           96.1 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                4.5 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          12.0 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.46 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.183 
_reflns.pdbx_Rpim_I_all                                0.082 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.983 
_reflns.pdbx_CC_star                                   0.996 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.162 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                0.162 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.90 
_reflns_shell.d_res_low                                     1.93 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.8 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1333 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               3.6 
_reflns_shell.pdbx_chi_squared                              1.065 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               1.41 
_reflns_shell.pdbx_Rpim_I_all                               0.719 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.33 
_reflns_shell.pdbx_CC_star                                  0.705 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          77.1 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.20 
_reflns_shell.pdbx_Rsym_value                               1.20 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               25.57 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8UIG 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.90 
_refine.ls_d_res_low                             34.82 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     33283 
_refine.ls_number_reflns_R_free                  1721 
_refine.ls_number_reflns_R_work                  31562 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    95.93 
_refine.ls_percent_reflns_R_free                 5.17 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1742 
_refine.ls_R_factor_R_free                       0.2132 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1722 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 20.9599 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2044 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.90 
_refine_hist.d_res_low                        34.82 
_refine_hist.number_atoms_solvent             187 
_refine_hist.number_atoms_total               3512 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        3325 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0045  ? 3409 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.7693  ? 4637 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0490  ? 522  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0046  ? 592  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.2876 ? 1204 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.90 1.96  . . 112 2116 77.63 . . . . 0.2389 . . . . . . . . . . . 0.2791 
'X-RAY DIFFRACTION' 1.96 2.02  . . 131 2611 95.14 . . . . 0.2195 . . . . . . . . . . . 0.2665 
'X-RAY DIFFRACTION' 2.02 2.09  . . 129 2693 98.22 . . . . 0.2020 . . . . . . . . . . . 0.2301 
'X-RAY DIFFRACTION' 2.09 2.18  . . 135 2689 98.12 . . . . 0.1834 . . . . . . . . . . . 0.2236 
'X-RAY DIFFRACTION' 2.18 2.27  . . 183 2649 98.40 . . . . 0.1839 . . . . . . . . . . . 0.2528 
'X-RAY DIFFRACTION' 2.27 2.39  . . 154 2660 98.63 . . . . 0.1809 . . . . . . . . . . . 0.2108 
'X-RAY DIFFRACTION' 2.39 2.54  . . 151 2603 94.97 . . . . 0.1842 . . . . . . . . . . . 0.2248 
'X-RAY DIFFRACTION' 2.54 2.74  . . 170 2702 98.69 . . . . 0.1875 . . . . . . . . . . . 0.2189 
'X-RAY DIFFRACTION' 2.74 3.02  . . 130 2711 98.82 . . . . 0.1806 . . . . . . . . . . . 0.2448 
'X-RAY DIFFRACTION' 3.02 3.45  . . 131 2726 98.48 . . . . 0.1821 . . . . . . . . . . . 0.2294 
'X-RAY DIFFRACTION' 3.45 4.35  . . 153 2644 96.18 . . . . 0.1432 . . . . . . . . . . . 0.1633 
'X-RAY DIFFRACTION' 4.35 34.82 . . 142 2758 97.84 . . . . 0.1402 . . . . . . . . . . . 0.1853 
# 
_struct.entry_id                     8UIG 
_struct.title                        'anti-Phosphohistidine Fab hSC44.ck.20 with 3pHis peptide' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8UIG 
_struct_keywords.text            
'ANTI-PHOSPHOHISTIDINE ANTIBODY POST-TRANSLATIONAL MODIFICATION ANTIBODY HUMANIZATION, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 4 ? 
F N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8UIG 8UIG ? 1 ? 1 
2 PDB 8UIG 8UIG ? 2 ? 1 
3 PDB 8UIG 8UIG ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8UIG H 1 ? 225 ? 8UIG 1 ? 221 ? 1 221 
2 2 8UIG L 1 ? 218 ? 8UIG 1 ? 212 ? 1 212 
3 3 8UIG C 1 ? 9   ? 8UIG 1 ? 9   ? 1 9   
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   trimeric 
_pdbx_struct_assembly.oligomeric_count     3 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 4620  ? 
1 MORE         -31   ? 
1 'SSA (A^2)'  19830 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 SER A 28  ? TYR A 32  ? SER H 28  TYR H 32  5 ? 5 
HELX_P HELX_P2 AA2 ARG A 86  ? THR A 90  ? ARG H 83  THR H 87  5 ? 5 
HELX_P HELX_P3 AA3 SER A 160 ? ALA A 162 ? SER H 156 ALA H 158 5 ? 3 
HELX_P HELX_P4 AA4 SER A 191 ? GLY A 194 ? SER H 187 GLY H 190 5 ? 4 
HELX_P HELX_P5 AA5 LYS A 205 ? ASN A 208 ? LYS H 201 ASN H 204 5 ? 4 
HELX_P HELX_P6 AA6 VAL B 29  B LYS B 33  ? VAL L 27  LYS L 31  5 ? 5 
HELX_P HELX_P7 AA7 GLN B 81  ? PHE B 85  ? GLN L 79  PHE L 83  5 ? 5 
HELX_P HELX_P8 AA8 SER B 127 ? LYS B 132 ? SER L 121 LYS L 126 1 ? 6 
HELX_P HELX_P9 AA9 LYS B 189 ? LYS B 194 ? LYS L 183 LYS L 188 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 22  SG ? ? ? 1_555 A CYS 95  SG ? ? H CYS 22  H CYS 92  1_555 ? ? ? ? ? ? ? 2.018 ? ? 
disulf2 disulf ?    ? A CYS 144 SG ? ? ? 1_555 A CYS 200 SG ? ? H CYS 140 H CYS 196 1_555 ? ? ? ? ? ? ? 2.040 ? ? 
disulf3 disulf ?    ? B CYS 23  SG ? ? ? 1_555 B CYS 90  SG A ? L CYS 23  L CYS 88  1_555 ? ? ? ? ? ? ? 2.065 ? ? 
disulf4 disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG A ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf5 disulf ?    ? B CYS 140 SG ? ? ? 1_555 B CYS 200 SG B ? L CYS 134 L CYS 194 1_555 ? ? ? ? ? ? ? 2.055 ? ? 
covale1 covale both ? C GLY 4   C  ? ? ? 1_555 C NEP 5   N  ? ? C GLY 4   C NEP 5   1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale2 covale both ? C NEP 5   C  ? ? ? 1_555 C ALA 6   N  ? ? C NEP 5   C ALA 6   1_555 ? ? ? ? ? ? ? 1.329 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 NEP C 5   ? .   . .   . NEP C 5   ? 1_555 .   . .   . .     .  .  HIS 1 NEP Phosphorylation 'Named protein modification' 
2 CYS A 22  ? CYS A 95  ? CYS H 22  ? 1_555 CYS H 92  ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
3 CYS A 144 ? CYS A 200 ? CYS H 140 ? 1_555 CYS H 196 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
4 CYS B 23  ? CYS B 90  A CYS L 23  ? 1_555 CYS L 88  ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
5 CYS B 140 ? CYS B 200 A CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
6 CYS B 140 ? CYS B 200 B CYS L 134 ? 1_555 CYS L 194 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 PHE 150 A . ? PHE 146 H PRO 151 A ? PRO 147 H 1 -6.37 
2 GLU 152 A . ? GLU 148 H PRO 153 A ? PRO 149 H 1 -1.53 
3 SER 7   B . ? SER 7   L PRO 8   B ? PRO 8   L 1 -3.24 
4 TYR 146 B . ? TYR 140 L PRO 147 B ? PRO 141 L 1 0.42  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 4 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? SER A 7   ? GLN H 3   SER H 7   
AA1 2 LEU A 18  ? SER A 25  ? LEU H 18  SER H 25  
AA1 3 THR A 77  ? MET A 82  ? THR H 77  MET H 82  
AA1 4 SER A 67  ? ASN A 72  ? SER H 67  ASN H 72  
AA2 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA2 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA2 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA2 4 PHE A 34  ? GLN A 39  ? PHE H 34  GLN H 39  
AA2 5 LEU A 45  ? LEU A 51  ? LEU H 45  LEU H 51  
AA2 6 ALA A 57  ? TYR A 59  ? ALA H 57  TYR H 59  
AA3 1 GLY A 10  ? VAL A 12  ? GLY H 10  VAL H 12  
AA3 2 THR A 111 ? VAL A 115 ? THR H 107 VAL H 111 
AA3 3 ALA A 91  ? LYS A 97  ? ALA H 88  LYS H 94  
AA3 4 ILE A 106 ? TRP A 107 ? ILE H 102 TRP H 103 
AA4 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA4 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA4 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA4 4 VAL A 167 ? THR A 169 ? VAL H 163 THR H 165 
AA5 1 SER A 124 ? LEU A 128 ? SER H 120 LEU H 124 
AA5 2 THR A 139 ? TYR A 149 ? THR H 135 TYR H 145 
AA5 3 TYR A 180 ? PRO A 189 ? TYR H 176 PRO H 185 
AA5 4 VAL A 173 ? LEU A 174 ? VAL H 169 LEU H 170 
AA6 1 THR A 155 ? TRP A 158 ? THR H 151 TRP H 154 
AA6 2 ILE A 199 ? HIS A 204 ? ILE H 195 HIS H 200 
AA6 3 THR A 209 ? LYS A 214 ? THR H 205 LYS H 210 
AA7 1 MET B 4   ? SER B 7   ? MET L 4   SER L 7   
AA7 2 VAL B 19  ? ALA B 25  ? VAL L 19  ALA L 25  
AA7 3 ASP B 72  ? ILE B 77  ? ASP L 70  ILE L 75  
AA7 4 PHE B 64  ? SER B 69  ? PHE L 62  SER L 67  
AA8 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA8 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA8 3 ALA B 86  ? SER B 96  ? ALA L 84  SER L 94  
AA8 4 VAL B 35  ? GLN B 40  ? VAL L 33  GLN L 38  
AA8 5 LYS B 47  ? TYR B 51  ? LYS L 45  TYR L 49  
AA8 6 SER B 55  ? LEU B 56  ? SER L 53  LEU L 54  
AA9 1 SER B 10  ? SER B 14  ? SER L 10  SER L 14  
AA9 2 THR B 108 ? LYS B 113 ? THR L 102 LYS L 107 
AA9 3 ALA B 86  ? SER B 96  ? ALA L 84  SER L 94  
AA9 4 ASP B 99  B PHE B 104 ? ASP L 95  PHE L 98  
AB1 1 SER B 120 ? PHE B 124 ? SER L 114 PHE L 118 
AB1 2 THR B 135 ? PHE B 145 ? THR L 129 PHE L 139 
AB1 3 TYR B 179 ? SER B 188 ? TYR L 173 SER L 182 
AB1 4 SER B 165 ? VAL B 169 ? SER L 159 VAL L 163 
AB2 1 ALA B 159 ? LEU B 160 ? ALA L 153 LEU L 154 
AB2 2 LYS B 151 ? VAL B 156 ? LYS L 145 VAL L 150 
AB2 3 VAL B 197 ? GLN B 204 ? VAL L 191 GLN L 198 
AB2 4 THR B 207 ? ASN B 214 ? THR L 201 ASN L 208 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER H 7   O SER A 21  ? O SER H 21  
AA1 2 3 N LEU A 20  ? N LEU H 20  O LEU A 80  ? O LEU H 80  
AA1 3 4 O THR A 79  ? O THR H 79  N THR A 70  ? N THR H 70  
AA2 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA2 2 3 O THR A 111 ? O THR H 107 N TYR A 93  ? N TYR H 90  
AA2 3 4 O ALA A 96  ? O ALA H 93  N SER A 35  ? N SER H 35  
AA2 4 5 N TRP A 36  ? N TRP H 36  O ILE A 48  ? O ILE H 48  
AA2 5 6 N TYR A 50  ? N TYR H 50  O PHE A 58  ? O PHE H 58  
AA3 1 2 N VAL A 12  ? N VAL H 12  O THR A 114 ? O THR H 110 
AA3 2 3 O THR A 111 ? O THR H 107 N TYR A 93  ? N TYR H 90  
AA3 3 4 N LYS A 97  ? N LYS H 94  O ILE A 106 ? O ILE H 102 
AA4 1 2 N PHE A 126 ? N PHE H 122 O LEU A 145 ? O LEU H 141 
AA4 2 3 N TYR A 149 ? N TYR H 145 O TYR A 180 ? O TYR H 176 
AA4 3 4 O VAL A 185 ? O VAL H 181 N HIS A 168 ? N HIS H 164 
AA5 1 2 N PHE A 126 ? N PHE H 122 O LEU A 145 ? O LEU H 141 
AA5 2 3 N TYR A 149 ? N TYR H 145 O TYR A 180 ? O TYR H 176 
AA5 3 4 O SER A 181 ? O SER H 177 N VAL A 173 ? N VAL H 169 
AA6 1 2 N SER A 157 ? N SER H 153 O ASN A 201 ? O ASN H 197 
AA6 2 3 N VAL A 202 ? N VAL H 198 O VAL A 211 ? O VAL H 207 
AA7 1 2 N SER B 7   ? N SER L 7   O THR B 22  ? O THR L 22  
AA7 2 3 N CYS B 23  ? N CYS L 23  O PHE B 73  ? O PHE L 71  
AA7 3 4 O THR B 76  ? O THR L 74  N SER B 65  ? N SER L 63  
AA8 1 2 N ALA B 13  ? N ALA L 13  O LYS B 113 ? O LYS L 107 
AA8 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA8 3 4 O THR B 87  ? O THR L 85  N GLN B 40  ? N GLN L 38  
AA8 4 5 N TRP B 37  ? N TRP L 35  O LEU B 49  ? O LEU L 47  
AA8 5 6 N TYR B 51  ? N TYR L 49  O SER B 55  ? O SER L 53  
AA9 1 2 N ALA B 13  ? N ALA L 13  O LYS B 113 ? O LYS L 107 
AA9 2 3 O VAL B 110 ? O VAL L 104 N ALA B 86  ? N ALA L 84  
AA9 3 4 N TYR B 94  ? N TYR L 92  O TYR B 101 D O TYR L 95  
AB1 1 2 N PHE B 122 ? N PHE L 116 O LEU B 141 ? O LEU L 135 
AB1 2 3 N PHE B 145 ? N PHE L 139 O TYR B 179 ? O TYR L 173 
AB1 3 4 O THR B 184 ? O THR L 178 N GLN B 166 ? N GLN L 160 
AB2 1 2 O ALA B 159 ? O ALA L 153 N VAL B 156 ? N VAL L 150 
AB2 2 3 N TYR B 155 ? N TYR L 149 O ALA B 199 ? O ALA L 193 
AB2 3 4 N VAL B 202 ? N VAL L 196 O VAL B 209 ? O VAL L 203 
# 
_pdbx_entry_details.entry_id                   8UIG 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ARG L 29  ? ? 57.66  16.76  
2 1 ILE L 51  ? ? 72.59  -52.37 
3 1 ALA L 84  ? ? 173.84 173.07 
4 1 ASN L 138 ? ? 56.80  72.19  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 H SER 215 ? A SER 219 
2 1 Y 1 H CYS 216 ? A CYS 220 
3 1 Y 1 H ASP 217 ? A ASP 221 
4 1 Y 1 H LYS 218 ? A LYS 222 
5 1 Y 1 H THR 219 ? A THR 223 
6 1 Y 1 H HIS 220 ? A HIS 224 
7 1 Y 1 H THR 221 ? A THR 225 
8 1 Y 1 C ALA 1   ? C ALA 1   
9 1 Y 1 C GLY 2   ? C GLY 2   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
NEP N    N N N 250 
NEP CA   C N S 251 
NEP C    C N N 252 
NEP O    O N N 253 
NEP CB   C N N 254 
NEP CG   C Y N 255 
NEP ND1  N Y N 256 
NEP CD2  C Y N 257 
NEP CE1  C Y N 258 
NEP NE2  N Y N 259 
NEP P    P N N 260 
NEP O1P  O N N 261 
NEP O2P  O N N 262 
NEP O3P  O N N 263 
NEP OXT  O N N 264 
NEP H    H N N 265 
NEP H2   H N N 266 
NEP HA   H N N 267 
NEP HB2  H N N 268 
NEP HB3  H N N 269 
NEP HD2  H N N 270 
NEP HE1  H N N 271 
NEP HOP1 H N N 272 
NEP HOP2 H N N 273 
NEP HXT  H N N 274 
PHE N    N N N 275 
PHE CA   C N S 276 
PHE C    C N N 277 
PHE O    O N N 278 
PHE CB   C N N 279 
PHE CG   C Y N 280 
PHE CD1  C Y N 281 
PHE CD2  C Y N 282 
PHE CE1  C Y N 283 
PHE CE2  C Y N 284 
PHE CZ   C Y N 285 
PHE OXT  O N N 286 
PHE H    H N N 287 
PHE H2   H N N 288 
PHE HA   H N N 289 
PHE HB2  H N N 290 
PHE HB3  H N N 291 
PHE HD1  H N N 292 
PHE HD2  H N N 293 
PHE HE1  H N N 294 
PHE HE2  H N N 295 
PHE HZ   H N N 296 
PHE HXT  H N N 297 
PRO N    N N N 298 
PRO CA   C N S 299 
PRO C    C N N 300 
PRO O    O N N 301 
PRO CB   C N N 302 
PRO CG   C N N 303 
PRO CD   C N N 304 
PRO OXT  O N N 305 
PRO H    H N N 306 
PRO HA   H N N 307 
PRO HB2  H N N 308 
PRO HB3  H N N 309 
PRO HG2  H N N 310 
PRO HG3  H N N 311 
PRO HD2  H N N 312 
PRO HD3  H N N 313 
PRO HXT  H N N 314 
SER N    N N N 315 
SER CA   C N S 316 
SER C    C N N 317 
SER O    O N N 318 
SER CB   C N N 319 
SER OG   O N N 320 
SER OXT  O N N 321 
SER H    H N N 322 
SER H2   H N N 323 
SER HA   H N N 324 
SER HB2  H N N 325 
SER HB3  H N N 326 
SER HG   H N N 327 
SER HXT  H N N 328 
THR N    N N N 329 
THR CA   C N S 330 
THR C    C N N 331 
THR O    O N N 332 
THR CB   C N R 333 
THR OG1  O N N 334 
THR CG2  C N N 335 
THR OXT  O N N 336 
THR H    H N N 337 
THR H2   H N N 338 
THR HA   H N N 339 
THR HB   H N N 340 
THR HG1  H N N 341 
THR HG21 H N N 342 
THR HG22 H N N 343 
THR HG23 H N N 344 
THR HXT  H N N 345 
TRP N    N N N 346 
TRP CA   C N S 347 
TRP C    C N N 348 
TRP O    O N N 349 
TRP CB   C N N 350 
TRP CG   C Y N 351 
TRP CD1  C Y N 352 
TRP CD2  C Y N 353 
TRP NE1  N Y N 354 
TRP CE2  C Y N 355 
TRP CE3  C Y N 356 
TRP CZ2  C Y N 357 
TRP CZ3  C Y N 358 
TRP CH2  C Y N 359 
TRP OXT  O N N 360 
TRP H    H N N 361 
TRP H2   H N N 362 
TRP HA   H N N 363 
TRP HB2  H N N 364 
TRP HB3  H N N 365 
TRP HD1  H N N 366 
TRP HE1  H N N 367 
TRP HE3  H N N 368 
TRP HZ2  H N N 369 
TRP HZ3  H N N 370 
TRP HH2  H N N 371 
TRP HXT  H N N 372 
TYR N    N N N 373 
TYR CA   C N S 374 
TYR C    C N N 375 
TYR O    O N N 376 
TYR CB   C N N 377 
TYR CG   C Y N 378 
TYR CD1  C Y N 379 
TYR CD2  C Y N 380 
TYR CE1  C Y N 381 
TYR CE2  C Y N 382 
TYR CZ   C Y N 383 
TYR OH   O N N 384 
TYR OXT  O N N 385 
TYR H    H N N 386 
TYR H2   H N N 387 
TYR HA   H N N 388 
TYR HB2  H N N 389 
TYR HB3  H N N 390 
TYR HD1  H N N 391 
TYR HD2  H N N 392 
TYR HE1  H N N 393 
TYR HE2  H N N 394 
TYR HH   H N N 395 
TYR HXT  H N N 396 
VAL N    N N N 397 
VAL CA   C N S 398 
VAL C    C N N 399 
VAL O    O N N 400 
VAL CB   C N N 401 
VAL CG1  C N N 402 
VAL CG2  C N N 403 
VAL OXT  O N N 404 
VAL H    H N N 405 
VAL H2   H N N 406 
VAL HA   H N N 407 
VAL HB   H N N 408 
VAL HG11 H N N 409 
VAL HG12 H N N 410 
VAL HG13 H N N 411 
VAL HG21 H N N 412 
VAL HG22 H N N 413 
VAL HG23 H N N 414 
VAL HXT  H N N 415 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
NEP N   CA   sing N N 237 
NEP N   H    sing N N 238 
NEP N   H2   sing N N 239 
NEP CA  C    sing N N 240 
NEP CA  CB   sing N N 241 
NEP CA  HA   sing N N 242 
NEP C   O    doub N N 243 
NEP C   OXT  sing N N 244 
NEP CB  CG   sing N N 245 
NEP CB  HB2  sing N N 246 
NEP CB  HB3  sing N N 247 
NEP CG  ND1  sing Y N 248 
NEP CG  CD2  doub Y N 249 
NEP ND1 CE1  doub Y N 250 
NEP CD2 NE2  sing Y N 251 
NEP CD2 HD2  sing N N 252 
NEP CE1 NE2  sing Y N 253 
NEP CE1 HE1  sing N N 254 
NEP NE2 P    sing N N 255 
NEP P   O1P  sing N N 256 
NEP P   O2P  sing N N 257 
NEP P   O3P  doub N N 258 
NEP O1P HOP1 sing N N 259 
NEP O2P HOP2 sing N N 260 
NEP OXT HXT  sing N N 261 
PHE N   CA   sing N N 262 
PHE N   H    sing N N 263 
PHE N   H2   sing N N 264 
PHE CA  C    sing N N 265 
PHE CA  CB   sing N N 266 
PHE CA  HA   sing N N 267 
PHE C   O    doub N N 268 
PHE C   OXT  sing N N 269 
PHE CB  CG   sing N N 270 
PHE CB  HB2  sing N N 271 
PHE CB  HB3  sing N N 272 
PHE CG  CD1  doub Y N 273 
PHE CG  CD2  sing Y N 274 
PHE CD1 CE1  sing Y N 275 
PHE CD1 HD1  sing N N 276 
PHE CD2 CE2  doub Y N 277 
PHE CD2 HD2  sing N N 278 
PHE CE1 CZ   doub Y N 279 
PHE CE1 HE1  sing N N 280 
PHE CE2 CZ   sing Y N 281 
PHE CE2 HE2  sing N N 282 
PHE CZ  HZ   sing N N 283 
PHE OXT HXT  sing N N 284 
PRO N   CA   sing N N 285 
PRO N   CD   sing N N 286 
PRO N   H    sing N N 287 
PRO CA  C    sing N N 288 
PRO CA  CB   sing N N 289 
PRO CA  HA   sing N N 290 
PRO C   O    doub N N 291 
PRO C   OXT  sing N N 292 
PRO CB  CG   sing N N 293 
PRO CB  HB2  sing N N 294 
PRO CB  HB3  sing N N 295 
PRO CG  CD   sing N N 296 
PRO CG  HG2  sing N N 297 
PRO CG  HG3  sing N N 298 
PRO CD  HD2  sing N N 299 
PRO CD  HD3  sing N N 300 
PRO OXT HXT  sing N N 301 
SER N   CA   sing N N 302 
SER N   H    sing N N 303 
SER N   H2   sing N N 304 
SER CA  C    sing N N 305 
SER CA  CB   sing N N 306 
SER CA  HA   sing N N 307 
SER C   O    doub N N 308 
SER C   OXT  sing N N 309 
SER CB  OG   sing N N 310 
SER CB  HB2  sing N N 311 
SER CB  HB3  sing N N 312 
SER OG  HG   sing N N 313 
SER OXT HXT  sing N N 314 
THR N   CA   sing N N 315 
THR N   H    sing N N 316 
THR N   H2   sing N N 317 
THR CA  C    sing N N 318 
THR CA  CB   sing N N 319 
THR CA  HA   sing N N 320 
THR C   O    doub N N 321 
THR C   OXT  sing N N 322 
THR CB  OG1  sing N N 323 
THR CB  CG2  sing N N 324 
THR CB  HB   sing N N 325 
THR OG1 HG1  sing N N 326 
THR CG2 HG21 sing N N 327 
THR CG2 HG22 sing N N 328 
THR CG2 HG23 sing N N 329 
THR OXT HXT  sing N N 330 
TRP N   CA   sing N N 331 
TRP N   H    sing N N 332 
TRP N   H2   sing N N 333 
TRP CA  C    sing N N 334 
TRP CA  CB   sing N N 335 
TRP CA  HA   sing N N 336 
TRP C   O    doub N N 337 
TRP C   OXT  sing N N 338 
TRP CB  CG   sing N N 339 
TRP CB  HB2  sing N N 340 
TRP CB  HB3  sing N N 341 
TRP CG  CD1  doub Y N 342 
TRP CG  CD2  sing Y N 343 
TRP CD1 NE1  sing Y N 344 
TRP CD1 HD1  sing N N 345 
TRP CD2 CE2  doub Y N 346 
TRP CD2 CE3  sing Y N 347 
TRP NE1 CE2  sing Y N 348 
TRP NE1 HE1  sing N N 349 
TRP CE2 CZ2  sing Y N 350 
TRP CE3 CZ3  doub Y N 351 
TRP CE3 HE3  sing N N 352 
TRP CZ2 CH2  doub Y N 353 
TRP CZ2 HZ2  sing N N 354 
TRP CZ3 CH2  sing Y N 355 
TRP CZ3 HZ3  sing N N 356 
TRP CH2 HH2  sing N N 357 
TRP OXT HXT  sing N N 358 
TYR N   CA   sing N N 359 
TYR N   H    sing N N 360 
TYR N   H2   sing N N 361 
TYR CA  C    sing N N 362 
TYR CA  CB   sing N N 363 
TYR CA  HA   sing N N 364 
TYR C   O    doub N N 365 
TYR C   OXT  sing N N 366 
TYR CB  CG   sing N N 367 
TYR CB  HB2  sing N N 368 
TYR CB  HB3  sing N N 369 
TYR CG  CD1  doub Y N 370 
TYR CG  CD2  sing Y N 371 
TYR CD1 CE1  sing Y N 372 
TYR CD1 HD1  sing N N 373 
TYR CD2 CE2  doub Y N 374 
TYR CD2 HD2  sing N N 375 
TYR CE1 CZ   doub Y N 376 
TYR CE1 HE1  sing N N 377 
TYR CE2 CZ   sing Y N 378 
TYR CE2 HE2  sing N N 379 
TYR CZ  OH   sing N N 380 
TYR OH  HH   sing N N 381 
TYR OXT HXT  sing N N 382 
VAL N   CA   sing N N 383 
VAL N   H    sing N N 384 
VAL N   H2   sing N N 385 
VAL CA  C    sing N N 386 
VAL CA  CB   sing N N 387 
VAL CA  HA   sing N N 388 
VAL C   O    doub N N 389 
VAL C   OXT  sing N N 390 
VAL CB  CG1  sing N N 391 
VAL CB  CG2  sing N N 392 
VAL CB  HB   sing N N 393 
VAL CG1 HG11 sing N N 394 
VAL CG1 HG12 sing N N 395 
VAL CG1 HG13 sing N N 396 
VAL CG2 HG21 sing N N 397 
VAL CG2 HG22 sing N N 398 
VAL CG2 HG23 sing N N 399 
VAL OXT HXT  sing N N 400 
# 
_pdbx_audit_support.funding_organization   'National Institutes of Health/National Cancer Institute (NIH/NCI)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           CA242443 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6X1V 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8UIG 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.022670 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.003270 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.013773 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.014367 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
P ? ? 9.51135 5.44231 ? ? 1.42069  35.72801 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . GLU A 1 1   ? 22.16456  -9.58287  36.19089  1.000 50.30991  ? 1   GLU H N    1 
ATOM   2    C CA   . GLU A 1 1   ? 22.38648  -10.91122 36.83288  1.000 61.67725  ? 1   GLU H CA   1 
ATOM   3    C C    . GLU A 1 1   ? 21.17544  -11.81408 36.60206  1.000 45.50753  ? 1   GLU H C    1 
ATOM   4    O O    . GLU A 1 1   ? 21.28454  -12.84572 35.93605  1.000 42.52302  ? 1   GLU H O    1 
ATOM   5    C CB   . GLU A 1 1   ? 22.66622  -10.74729 38.33118  1.000 64.97901  ? 1   GLU H CB   1 
ATOM   6    C CG   . GLU A 1 1   ? 23.44689  -11.90350 38.95123  1.000 67.42122  ? 1   GLU H CG   1 
ATOM   7    C CD   . GLU A 1 1   ? 22.57742  -13.11553 39.23799  1.000 73.99273  ? 1   GLU H CD   1 
ATOM   8    O OE1  . GLU A 1 1   ? 21.67206  -13.00707 40.09535  1.000 67.52186  ? 1   GLU H OE1  1 
ATOM   9    O OE2  . GLU A 1 1   ? 22.79451  -14.17201 38.60172  1.000 60.77961  ? 1   GLU H OE2  1 
ATOM   10   H H1   . GLU A 1 1   ? 22.87321  -9.06320  36.33178  1.000 60.37872  ? 1   GLU H H1   1 
ATOM   11   H H2   . GLU A 1 1   ? 22.04633  -9.69246  35.31561  1.000 60.37872  ? 1   GLU H H2   1 
ATOM   12   H H3   . GLU A 1 1   ? 21.44175  -9.20059  36.54233  1.000 60.37872  ? 1   GLU H H3   1 
ATOM   13   H HA   . GLU A 1 1   ? 23.16409  -11.33946 36.44195  1.000 74.01954  ? 1   GLU H HA   1 
ATOM   14   H HB2  . GLU A 1 1   ? 23.18422  -9.93790  38.46332  1.000 77.98165  ? 1   GLU H HB2  1 
ATOM   15   H HB3  . GLU A 1 1   ? 21.81935  -10.67931 38.79926  1.000 77.98165  ? 1   GLU H HB3  1 
ATOM   16   H HG2  . GLU A 1 1   ? 24.14775  -12.17584 38.33842  1.000 80.91229  ? 1   GLU H HG2  1 
ATOM   17   H HG3  . GLU A 1 1   ? 23.83544  -11.60846 39.78962  1.000 80.91229  ? 1   GLU H HG3  1 
ATOM   18   N N    . VAL A 1 2   ? 20.01695  -11.43010 37.14282  1.000 42.89185  ? 2   VAL H N    1 
ATOM   19   C CA   . VAL A 1 2   ? 18.81268  -12.21530 36.90983  1.000 32.65932  ? 2   VAL H CA   1 
ATOM   20   C C    . VAL A 1 2   ? 18.38940  -12.04138 35.46073  1.000 30.67030  ? 2   VAL H C    1 
ATOM   21   O O    . VAL A 1 2   ? 18.52050  -10.95596 34.87844  1.000 26.86040  ? 2   VAL H O    1 
ATOM   22   C CB   . VAL A 1 2   ? 17.67705  -11.81452 37.86635  1.000 33.86898  ? 2   VAL H CB   1 
ATOM   23   C CG1  . VAL A 1 2   ? 18.18220  -11.74262 39.30287  1.000 40.14649  ? 2   VAL H CG1  1 
ATOM   24   C CG2  . VAL A 1 2   ? 17.04139  -10.50137 37.43014  1.000 28.75577  ? 2   VAL H CG2  1 
ATOM   25   H H    . VAL A 1 2   ? 19.90794  -10.73441 37.63651  1.000 51.47705  ? 2   VAL H H    1 
ATOM   26   H HA   . VAL A 1 2   ? 19.01377  -13.14862 37.08122  1.000 39.19802  ? 2   VAL H HA   1 
ATOM   27   H HB   . VAL A 1 2   ? 16.98616  -12.49467 37.83518  1.000 40.64960  ? 2   VAL H HB   1 
ATOM   28   H HG11 . VAL A 1 2   ? 17.42427  -11.63956 39.89937  1.000 48.18263  ? 2   VAL H HG11 1 
ATOM   29   H HG12 . VAL A 1 2   ? 18.65841  -12.56151 39.51153  1.000 48.18263  ? 2   VAL H HG12 1 
ATOM   30   H HG13 . VAL A 1 2   ? 18.77788  -10.98209 39.39046  1.000 48.18263  ? 2   VAL H HG13 1 
ATOM   31   H HG21 . VAL A 1 2   ? 16.52173  -10.14220 38.16625  1.000 34.51376  ? 2   VAL H HG21 1 
ATOM   32   H HG22 . VAL A 1 2   ? 17.74232  -9.87741  37.18464  1.000 34.51376  ? 2   VAL H HG22 1 
ATOM   33   H HG23 . VAL A 1 2   ? 16.46462  -10.66748 36.66814  1.000 34.51376  ? 2   VAL H HG23 1 
ATOM   34   N N    . GLN A 1 3   ? 17.88797  -13.11509 34.86456  1.000 25.79865  ? 3   GLN H N    1 
ATOM   35   C CA   . GLN A 1 3   ? 17.50553  -13.05682 33.46826  1.000 24.02502  ? 3   GLN H CA   1 
ATOM   36   C C    . GLN A 1 3   ? 16.40449  -14.06948 33.20360  1.000 22.92249  ? 3   GLN H C    1 
ATOM   37   O O    . GLN A 1 3   ? 16.23083  -15.04465 33.93962  1.000 20.93287  ? 3   GLN H O    1 
ATOM   38   C CB   . GLN A 1 3   ? 18.70376  -13.31921 32.55409  1.000 29.76728  ? 3   GLN H CB   1 
ATOM   39   C CG   . GLN A 1 3   ? 18.61367  -12.62063 31.20912  1.000 47.07862  ? 3   GLN H CG   1 
ATOM   40   C CD   . GLN A 1 3   ? 19.71719  -13.04586 30.25885  1.000 52.63741  ? 3   GLN H CD   1 
ATOM   41   O OE1  . GLN A 1 3   ? 20.60390  -13.82033 30.62706  1.000 45.27152  ? 3   GLN H OE1  1 
ATOM   42   N NE2  . GLN A 1 3   ? 19.66457  -12.54661 29.02611  1.000 54.64125  ? 3   GLN H NE2  1 
ATOM   43   H H    . GLN A 1 3   ? 17.76259  -13.87635 35.24450  1.000 30.96521  ? 3   GLN H H    1 
ATOM   44   H HA   . GLN A 1 3   ? 17.15216  -12.17540 33.27048  1.000 28.83686  ? 3   GLN H HA   1 
ATOM   45   H HB2  . GLN A 1 3   ? 19.50792  -13.00593 32.99690  1.000 35.72757  ? 3   GLN H HB2  1 
ATOM   46   H HB3  . GLN A 1 3   ? 18.76630  -14.27292 32.38850  1.000 35.72757  ? 3   GLN H HB3  1 
ATOM   47   H HG2  . GLN A 1 3   ? 17.76222  -12.83505 30.79687  1.000 56.50117  ? 3   GLN H HG2  1 
ATOM   48   H HG3  . GLN A 1 3   ? 18.68510  -11.66271 31.34397  1.000 56.50117  ? 3   GLN H HG3  1 
ATOM   49   H HE21 . GLN A 1 3   ? 19.02754  -12.01276 28.80521  1.000 65.57633  ? 3   GLN H HE21 1 
ATOM   50   H HE22 . GLN A 1 3   ? 20.26761  -12.75788 28.45052  1.000 65.57633  ? 3   GLN H HE22 1 
ATOM   51   N N    . LEU A 1 4   ? 15.65803  -13.80656 32.13637  1.000 17.85761  ? 4   LEU H N    1 
ATOM   52   C CA   . LEU A 1 4   ? 14.63061  -14.69745 31.61484  1.000 23.63979  ? 4   LEU H CA   1 
ATOM   53   C C    . LEU A 1 4   ? 14.93466  -14.81868 30.12828  1.000 20.65790  ? 4   LEU H C    1 
ATOM   54   O O    . LEU A 1 4   ? 14.73773  -13.85874 29.37266  1.000 20.15948  ? 4   LEU H O    1 
ATOM   55   C CB   . LEU A 1 4   ? 13.23214  -14.13855 31.88665  1.000 23.53171  ? 4   LEU H CB   1 
ATOM   56   C CG   . LEU A 1 4   ? 12.04672  -15.09390 32.02658  1.000 25.68975  ? 4   LEU H CG   1 
ATOM   57   C CD1  . LEU A 1 4   ? 12.33463  -16.22960 33.00155  1.000 25.94878  ? 4   LEU H CD1  1 
ATOM   58   C CD2  . LEU A 1 4   ? 10.81378  -14.31007 32.47841  1.000 24.09066  ? 4   LEU H CD2  1 
ATOM   59   H H    . LEU A 1 4   ? 15.73259  -13.08371 31.67646  1.000 21.43596  ? 4   LEU H H    1 
ATOM   60   H HA   . LEU A 1 4   ? 14.65904  -15.57597 32.02507  1.000 28.37458  ? 4   LEU H HA   1 
ATOM   61   H HB2  . LEU A 1 4   ? 13.27814  -13.64061 32.71782  1.000 28.24489  ? 4   LEU H HB2  1 
ATOM   62   H HB3  . LEU A 1 4   ? 13.01375  -13.54161 31.15394  1.000 28.24489  ? 4   LEU H HB3  1 
ATOM   63   H HG   . LEU A 1 4   ? 11.87675  -15.50234 31.16333  1.000 30.83453  ? 4   LEU H HG   1 
ATOM   64   H HD11 . LEU A 1 4   ? 11.50372  -16.68403 33.21129  1.000 31.14536  ? 4   LEU H HD11 1 
ATOM   65   H HD12 . LEU A 1 4   ? 12.95595  -16.84994 32.58918  1.000 31.14536  ? 4   LEU H HD12 1 
ATOM   66   H HD13 . LEU A 1 4   ? 12.72317  -15.86075 33.81018  1.000 31.14536  ? 4   LEU H HD13 1 
ATOM   67   H HD21 . LEU A 1 4   ? 10.03241  -14.87997 32.40375  1.000 28.91563  ? 4   LEU H HD21 1 
ATOM   68   H HD22 . LEU A 1 4   ? 10.93524  -14.03438 33.40044  1.000 28.91563  ? 4   LEU H HD22 1 
ATOM   69   H HD23 . LEU A 1 4   ? 10.70988  -13.53027 31.91094  1.000 28.91563  ? 4   LEU H HD23 1 
ATOM   70   N N    . VAL A 1 5   ? 15.45706  -15.97084 29.71250  1.000 19.42633  ? 5   VAL H N    1 
ATOM   71   C CA   . VAL A 1 5   ? 15.93097  -16.16903 28.34493  1.000 21.57313  ? 5   VAL H CA   1 
ATOM   72   C C    . VAL A 1 5   ? 14.90510  -16.99481 27.58441  1.000 22.21945  ? 5   VAL H C    1 
ATOM   73   O O    . VAL A 1 5   ? 14.63665  -18.14801 27.93771  1.000 20.24114  ? 5   VAL H O    1 
ATOM   74   C CB   . VAL A 1 5   ? 17.30950  -16.84614 28.31697  1.000 20.61411  ? 5   VAL H CB   1 
ATOM   75   C CG1  . VAL A 1 5   ? 17.71034  -17.15196 26.88512  1.000 23.01906  ? 5   VAL H CG1  1 
ATOM   76   C CG2  . VAL A 1 5   ? 18.33951  -15.95348 28.97619  1.000 24.90652  ? 5   VAL H CG2  1 
ATOM   77   H H    . VAL A 1 5   ? 15.54878  -16.66390 30.21335  1.000 23.31843  ? 5   VAL H H    1 
ATOM   78   H HA   . VAL A 1 5   ? 16.00208  -15.30358 27.91268  1.000 25.89459  ? 5   VAL H HA   1 
ATOM   79   H HB   . VAL A 1 5   ? 17.26854  -17.68141 28.80845  1.000 24.74377  ? 5   VAL H HB   1 
ATOM   80   H HG11 . VAL A 1 5   ? 18.66346  -17.32957 26.85507  1.000 27.62970  ? 5   VAL H HG11 1 
ATOM   81   H HG12 . VAL A 1 5   ? 17.21901  -17.93029 26.57901  1.000 27.62970  ? 5   VAL H HG12 1 
ATOM   82   H HG13 . VAL A 1 5   ? 17.49870  -16.38688 26.32767  1.000 27.62970  ? 5   VAL H HG13 1 
ATOM   83   H HG21 . VAL A 1 5   ? 19.20604  -16.38747 28.93524  1.000 29.89466  ? 5   VAL H HG21 1 
ATOM   84   H HG22 . VAL A 1 5   ? 18.37124  -15.10633 28.50478  1.000 29.89466  ? 5   VAL H HG22 1 
ATOM   85   H HG23 . VAL A 1 5   ? 18.08577  -15.80807 29.90106  1.000 29.89466  ? 5   VAL H HG23 1 
ATOM   86   N N    . GLU A 1 6   ? 14.36006  -16.41237 26.52598  1.000 20.07010  ? 6   GLU H N    1 
ATOM   87   C CA   . GLU A 1 6   ? 13.26822  -16.99652 25.76740  1.000 21.85132  ? 6   GLU H CA   1 
ATOM   88   C C    . GLU A 1 6   ? 13.80574  -17.73366 24.54731  1.000 25.69665  ? 6   GLU H C    1 
ATOM   89   O O    . GLU A 1 6   ? 14.71859  -17.25320 23.87164  1.000 20.77548  ? 6   GLU H O    1 
ATOM   90   C CB   . GLU A 1 6   ? 12.30009  -15.89326 25.34501  1.000 25.41558  ? 6   GLU H CB   1 
ATOM   91   C CG   . GLU A 1 6   ? 11.01242  -16.37976 24.76197  1.000 24.92926  ? 6   GLU H CG   1 
ATOM   92   C CD   . GLU A 1 6   ? 10.02614  -15.25102 24.57579  1.000 25.89911  ? 6   GLU H CD   1 
ATOM   93   O OE1  . GLU A 1 6   ? 10.25968  -14.15359 25.14250  1.000 23.99932  ? 6   GLU H OE1  1 
ATOM   94   O OE2  . GLU A 1 6   ? 9.02497   -15.46659 23.86338  1.000 23.28306  ? 6   GLU H OE2  1 
ATOM   95   H H    . GLU A 1 6   ? 14.61569  -15.65119 26.21797  1.000 24.09096  ? 6   GLU H H    1 
ATOM   96   H HA   . GLU A 1 6   ? 12.79032  -17.64659 26.30585  1.000 26.22842  ? 6   GLU H HA   1 
ATOM   97   H HB2  . GLU A 1 6   ? 12.08377  -15.35830 26.12470  1.000 30.50553  ? 6   GLU H HB2  1 
ATOM   98   H HB3  . GLU A 1 6   ? 12.73428  -15.34254 24.67488  1.000 30.50553  ? 6   GLU H HB3  1 
ATOM   99   H HG2  . GLU A 1 6   ? 11.18393  -16.78098 23.89565  1.000 29.92194  ? 6   GLU H HG2  1 
ATOM   100  H HG3  . GLU A 1 6   ? 10.61741  -17.03470 25.35856  1.000 29.92194  ? 6   GLU H HG3  1 
ATOM   101  N N    . SER A 1 7   ? 13.22666  -18.89967 24.26388  1.000 19.91800  ? 7   SER H N    1 
ATOM   102  C CA   . SER A 1 7   ? 13.66372  -19.74108 23.16262  1.000 25.68421  ? 7   SER H CA   1 
ATOM   103  C C    . SER A 1 7   ? 12.46702  -20.40395 22.49801  1.000 40.36477  ? 7   SER H C    1 
ATOM   104  O O    . SER A 1 7   ? 11.54002  -20.88609 23.16640  1.000 24.72533  ? 7   SER H O    1 
ATOM   105  C CB   . SER A 1 7   ? 14.65745  -20.81076 23.63783  1.000 41.78176  ? 7   SER H CB   1 
ATOM   106  O OG   . SER A 1 7   ? 13.98859  -21.90132 24.24393  1.000 53.38761  ? 7   SER H OG   1 
ATOM   107  H H    . SER A 1 7   ? 12.56606  -19.22747 24.70632  1.000 23.90843  ? 7   SER H H    1 
ATOM   108  H HA   . SER A 1 7   ? 14.09892  -19.18723 22.49572  1.000 30.82789  ? 7   SER H HA   1 
ATOM   109  H HB2  . SER A 1 7   ? 15.15850  -21.13547 22.87336  1.000 50.14495  ? 7   SER H HB2  1 
ATOM   110  H HB3  . SER A 1 7   ? 15.26058  -20.41338 24.28530  1.000 50.14495  ? 7   SER H HB3  1 
ATOM   111  H HG   . SER A 1 7   ? 14.54059  -22.50268 24.44209  1.000 64.07197  ? 7   SER H HG   1 
ATOM   112  N N    . GLY A 1 8   ? 12.52647  -20.44959 21.16825  1.000 40.29250  ? 8   GLY H N    1 
ATOM   113  C CA   . GLY A 1 8   ? 11.46832  -20.85704 20.27861  1.000 37.72526  ? 8   GLY H CA   1 
ATOM   114  C C    . GLY A 1 8   ? 11.36281  -19.85217 19.15573  1.000 35.38007  ? 8   GLY H C    1 
ATOM   115  O O    . GLY A 1 8   ? 12.28909  -19.07214 18.90448  1.000 42.57604  ? 8   GLY H O    1 
ATOM   116  H H    . GLY A 1 8   ? 13.23367  -20.22850 20.73169  1.000 48.35783  ? 8   GLY H H    1 
ATOM   117  H HA2  . GLY A 1 8   ? 11.66022  -21.73264 19.90794  1.000 45.27715  ? 8   GLY H HA2  1 
ATOM   118  H HA3  . GLY A 1 8   ? 10.62457  -20.89408 20.75569  1.000 45.27715  ? 8   GLY H HA3  1 
ATOM   119  N N    . GLY A 1 9   ? 10.22597  -19.85678 18.47920  1.000 43.69484  ? 9   GLY H N    1 
ATOM   120  C CA   . GLY A 1 9   ? 9.94631   -18.82916 17.50204  1.000 35.77068  ? 9   GLY H CA   1 
ATOM   121  C C    . GLY A 1 9   ? 10.25313  -19.27718 16.08413  1.000 36.54754  ? 9   GLY H C    1 
ATOM   122  O O    . GLY A 1 9   ? 11.02587  -20.20822 15.83989  1.000 31.53141  ? 9   GLY H O    1 
ATOM   123  H H    . GLY A 1 9   ? 9.60455   -20.44425 18.57037  1.000 52.44064  ? 9   GLY H H    1 
ATOM   124  H HA2  . GLY A 1 9   ? 9.00793   -18.58817 17.54963  1.000 42.93165  ? 9   GLY H HA2  1 
ATOM   125  H HA3  . GLY A 1 9   ? 10.48386  -18.04578 17.69763  1.000 42.93165  ? 9   GLY H HA3  1 
ATOM   126  N N    . GLY A 1 10  ? 9.63593   -18.58020 15.13371  1.000 23.45318  ? 10  GLY H N    1 
ATOM   127  C CA   . GLY A 1 10  ? 9.79110   -18.89757 13.73318  1.000 24.97393  ? 10  GLY H CA   1 
ATOM   128  C C    . GLY A 1 10  ? 8.46319   -19.16653 13.05965  1.000 20.14826  ? 10  GLY H C    1 
ATOM   129  O O    . GLY A 1 10  ? 7.40834   -18.71920 13.52760  1.000 21.79164  ? 10  GLY H O    1 
ATOM   130  H H    . GLY A 1 10  ? 9.11654   -17.91135 15.28361  1.000 28.15064  ? 10  GLY H H    1 
ATOM   131  H HA2  . GLY A 1 10  ? 10.22017  -18.15475 13.28038  1.000 29.97555  ? 10  GLY H HA2  1 
ATOM   132  H HA3  . GLY A 1 10  ? 10.34727  -19.68700 13.64167  1.000 29.97555  ? 10  GLY H HA3  1 
ATOM   133  N N    . LEU A 1 11  ? 8.51362   -19.90109 11.95374  1.000 20.87624  ? 11  LEU H N    1 
ATOM   134  C CA   . LEU A 1 11  ? 7.35702   -20.12647 11.10405  1.000 18.22694  ? 11  LEU H CA   1 
ATOM   135  C C    . LEU A 1 11  ? 6.62222   -21.39162 11.52217  1.000 20.56939  ? 11  LEU H C    1 
ATOM   136  O O    . LEU A 1 11  ? 7.24023   -22.42365 11.79339  1.000 21.86534  ? 11  LEU H O    1 
ATOM   137  C CB   . LEU A 1 11  ? 7.79352   -20.24161 9.64368   1.000 20.68998  ? 11  LEU H CB   1 
ATOM   138  C CG   . LEU A 1 11  ? 6.69833   -20.41431 8.59176   1.000 25.16157  ? 11  LEU H CG   1 
ATOM   139  C CD1  . LEU A 1 11  ? 5.76606   -19.22772 8.58226   1.000 24.17286  ? 11  LEU H CD1  1 
ATOM   140  C CD2  . LEU A 1 11  ? 7.32179   -20.60156 7.22436   1.000 27.98584  ? 11  LEU H CD2  1 
ATOM   141  H H    . LEU A 1 11  ? 9.22648   -20.28877 11.66890  1.000 25.05832  ? 11  LEU H H    1 
ATOM   142  H HA   . LEU A 1 11  ? 6.74314   -19.38045 11.19070  1.000 21.87916  ? 11  LEU H HA   1 
ATOM   143  H HB2  . LEU A 1 11  ? 8.27811   -19.43322 9.41439   1.000 24.83481  ? 11  LEU H HB2  1 
ATOM   144  H HB3  . LEU A 1 11  ? 8.37862   -21.01165 9.56888   1.000 24.83481  ? 11  LEU H HB3  1 
ATOM   145  H HG   . LEU A 1 11  ? 6.17394   -21.20106 8.80841   1.000 30.20071  ? 11  LEU H HG   1 
ATOM   146  H HD11 . LEU A 1 11  ? 5.16640   -19.30331 7.82358   1.000 29.01427  ? 11  LEU H HD11 1 
ATOM   147  H HD12 . LEU A 1 11  ? 5.25618   -19.22009 9.40741   1.000 29.01427  ? 11  LEU H HD12 1 
ATOM   148  H HD13 . LEU A 1 11  ? 6.29029   -18.41480 8.50983   1.000 29.01427  ? 11  LEU H HD13 1 
ATOM   149  H HD21 . LEU A 1 11  ? 6.61602   -20.68227 6.56386   1.000 33.58984  ? 11  LEU H HD21 1 
ATOM   150  H HD22 . LEU A 1 11  ? 7.87731   -19.83242 7.02255   1.000 33.58984  ? 11  LEU H HD22 1 
ATOM   151  H HD23 . LEU A 1 11  ? 7.86208   -21.40714 7.23126   1.000 33.58984  ? 11  LEU H HD23 1 
ATOM   152  N N    . VAL A 1 12  ? 5.29653   -21.30177 11.56560  1.000 18.76161  ? 12  VAL H N    1 
ATOM   153  C CA   . VAL A 1 12  ? 4.41995   -22.41776 11.89791  1.000 18.57287  ? 12  VAL H CA   1 
ATOM   154  C C    . VAL A 1 12  ? 3.31304   -22.46001 10.85397  1.000 22.91338  ? 12  VAL H C    1 
ATOM   155  O O    . VAL A 1 12  ? 2.77711   -21.41572 10.46745  1.000 19.27515  ? 12  VAL H O    1 
ATOM   156  C CB   . VAL A 1 12  ? 3.82334   -22.27841 13.31485  1.000 19.78056  ? 12  VAL H CB   1 
ATOM   157  C CG1  . VAL A 1 12  ? 2.81015   -23.40099 13.58087  1.000 21.11859  ? 12  VAL H CG1  1 
ATOM   158  C CG2  . VAL A 1 12  ? 4.92577   -22.27145 14.35635  1.000 25.98276  ? 12  VAL H CG2  1 
ATOM   159  H H    . VAL A 1 12  ? 4.86596   -20.57602 11.39980  1.000 22.52077  ? 12  VAL H H    1 
ATOM   160  H HA   . VAL A 1 12  ? 4.92026   -23.24816 11.86609  1.000 22.29428  ? 12  VAL H HA   1 
ATOM   161  H HB   . VAL A 1 12  ? 3.35178   -21.43335 13.38118  1.000 23.74350  ? 12  VAL H HB   1 
ATOM   162  H HG11 . VAL A 1 12  ? 2.65628   -23.46766 14.53627  1.000 25.34915  ? 12  VAL H HG11 1 
ATOM   163  H HG12 . VAL A 1 12  ? 1.97957   -23.19110 13.12592  1.000 25.34915  ? 12  VAL H HG12 1 
ATOM   164  H HG13 . VAL A 1 12  ? 3.16942   -24.23689 13.24457  1.000 25.34915  ? 12  VAL H HG13 1 
ATOM   165  H HG21 . VAL A 1 12  ? 4.52702   -22.20143 15.23782  1.000 31.18615  ? 12  VAL H HG21 1 
ATOM   166  H HG22 . VAL A 1 12  ? 5.43133   -23.09634 14.28658  1.000 31.18615  ? 12  VAL H HG22 1 
ATOM   167  H HG23 . VAL A 1 12  ? 5.50762   -21.51225 14.19525  1.000 31.18615  ? 12  VAL H HG23 1 
ATOM   168  N N    . GLN A 1 13  ? 2.98150   -23.66370 10.38171  1.000 22.32166  ? 13  GLN H N    1 
ATOM   169  C CA   . GLN A 1 13  ? 1.89901   -23.76697 9.41384   1.000 24.28345  ? 13  GLN H CA   1 
ATOM   170  C C    . GLN A 1 13  ? 0.54994   -23.62037 10.11548  1.000 19.03230  ? 13  GLN H C    1 
ATOM   171  O O    . GLN A 1 13  ? 0.39047   -24.05596 11.25907  1.000 21.37529  ? 13  GLN H O    1 
ATOM   172  C CB   . GLN A 1 13  ? 1.95290   -25.10628 8.68764   1.000 28.36948  ? 13  GLN H CB   1 
ATOM   173  C CG   . GLN A 1 13  ? 3.23713   -25.33765 7.90919   1.000 33.77208  ? 13  GLN H CG   1 
ATOM   174  C CD   . GLN A 1 13  ? 3.44189   -24.32102 6.80599   1.000 40.20974  ? 13  GLN H CD   1 
ATOM   175  O OE1  . GLN A 1 13  ? 2.58506   -24.15408 5.94079   1.000 47.21280  ? 13  GLN H OE1  1 
ATOM   176  N NE2  . GLN A 1 13  ? 4.58256   -23.63094 6.83178   1.000 42.38655  ? 13  GLN H NE2  1 
ATOM   177  H H    . GLN A 1 13  ? 3.35645   -24.40618 10.60020  1.000 26.79282  ? 13  GLN H H    1 
ATOM   178  H HA   . GLN A 1 13  ? 1.98549   -23.06261 8.75255   1.000 29.14697  ? 13  GLN H HA   1 
ATOM   179  H HB2  . GLN A 1 13  ? 1.87245   -25.81784 9.34193   1.000 34.05021  ? 13  GLN H HB2  1 
ATOM   180  H HB3  . GLN A 1 13  ? 1.21537   -25.14866 8.05903   1.000 34.05021  ? 13  GLN H HB3  1 
ATOM   181  H HG2  . GLN A 1 13  ? 3.99078   -25.27730 8.51687   1.000 40.53333  ? 13  GLN H HG2  1 
ATOM   182  H HG3  . GLN A 1 13  ? 3.20730   -26.21851 7.50410   1.000 40.53333  ? 13  GLN H HG3  1 
ATOM   183  H HE21 . GLN A 1 13  ? 5.15791   -23.77436 7.45468   1.000 50.87069  ? 13  GLN H HE21 1 
ATOM   184  H HE22 . GLN A 1 13  ? 4.74290   -23.04245 6.22551   1.000 50.87069  ? 13  GLN H HE22 1 
ATOM   185  N N    . PRO A 1 14  ? -0.43831  -23.01243 9.45698   1.000 22.24580  ? 14  PRO H N    1 
ATOM   186  C CA   . PRO A 1 14  ? -1.76967  -22.92378 10.06714  1.000 18.98585  ? 14  PRO H CA   1 
ATOM   187  C C    . PRO A 1 14  ? -2.25852  -24.29772 10.48845  1.000 23.93141  ? 14  PRO H C    1 
ATOM   188  O O    . PRO A 1 14  ? -2.05354  -25.29561 9.79244   1.000 23.66811  ? 14  PRO H O    1 
ATOM   189  C CB   . PRO A 1 14  ? -2.63844  -22.32634 8.95700   1.000 26.34997  ? 14  PRO H CB   1 
ATOM   190  C CG   . PRO A 1 14  ? -1.67985  -21.58042 8.09199   1.000 31.45432  ? 14  PRO H CG   1 
ATOM   191  C CD   . PRO A 1 14  ? -0.40788  -22.38692 8.12125   1.000 28.88578  ? 14  PRO H CD   1 
ATOM   192  H HA   . PRO A 1 14  ? -1.76506  -22.32247 10.82827  1.000 22.78985  ? 14  PRO H HA   1 
ATOM   193  H HB2  . PRO A 1 14  ? -3.07711  -23.03515 8.46095   1.000 31.62680  ? 14  PRO H HB2  1 
ATOM   194  H HB3  . PRO A 1 14  ? -3.30096  -21.72950 9.33878   1.000 31.62680  ? 14  PRO H HB3  1 
ATOM   195  H HG2  . PRO A 1 14  ? -2.02957  -21.51923 7.18930   1.000 37.75202  ? 14  PRO H HG2  1 
ATOM   196  H HG3  . PRO A 1 14  ? -1.53391  -20.69169 8.45219   1.000 37.75202  ? 14  PRO H HG3  1 
ATOM   197  H HD2  . PRO A 1 14  ? -0.40957  -23.06088 7.42362   1.000 34.66977  ? 14  PRO H HD2  1 
ATOM   198  H HD3  . PRO A 1 14  ? 0.36802   -21.81266 8.02587   1.000 34.66977  ? 14  PRO H HD3  1 
ATOM   199  N N    . GLY A 1 15  ? -2.90890  -24.33935 11.64650  1.000 18.26188  ? 15  GLY H N    1 
ATOM   200  C CA   . GLY A 1 15  ? -3.27369  -25.58417 12.27289  1.000 19.79862  ? 15  GLY H CA   1 
ATOM   201  C C    . GLY A 1 15  ? -2.16281  -26.22995 13.06072  1.000 19.06803  ? 15  GLY H C    1 
ATOM   202  O O    . GLY A 1 15  ? -2.42024  -27.20420 13.77408  1.000 20.67602  ? 15  GLY H O    1 
ATOM   203  H H    . GLY A 1 15  ? -3.15028  -23.64305 12.08979  1.000 21.92109  ? 15  GLY H H    1 
ATOM   204  H HA2  . GLY A 1 15  ? -4.01492  -25.42459 12.87787  1.000 23.76517  ? 15  GLY H HA2  1 
ATOM   205  H HA3  . GLY A 1 15  ? -3.55517  -26.20912 11.58652  1.000 23.76517  ? 15  GLY H HA3  1 
ATOM   206  N N    . GLY A 1 16  ? -0.93875  -25.72135 12.95762  1.000 18.66757  ? 16  GLY H N    1 
ATOM   207  C CA   . GLY A 1 16  ? 0.18043   -26.24346 13.70827  1.000 19.04903  ? 16  GLY H CA   1 
ATOM   208  C C    . GLY A 1 16  ? 0.20244   -25.70764 15.12603  1.000 23.49942  ? 16  GLY H C    1 
ATOM   209  O O    . GLY A 1 16  ? -0.74010  -25.07519 15.60436  1.000 19.09552  ? 16  GLY H O    1 
ATOM   210  H H    . GLY A 1 16  ? -0.73368  -25.06016 12.44735  1.000 22.40792  ? 16  GLY H H    1 
ATOM   211  H HA2  . GLY A 1 16  ? 0.12272   -27.21105 13.74486  1.000 22.86567  ? 16  GLY H HA2  1 
ATOM   212  H HA3  . GLY A 1 16  ? 1.00906   -25.99284 13.27070  1.000 22.86567  ? 16  GLY H HA3  1 
ATOM   213  N N    . SER A 1 17  ? 1.31735   -25.97077 15.80685  1.000 20.10183  ? 17  SER H N    1 
ATOM   214  C CA   . SER A 1 17  ? 1.47561   -25.62919 17.21141  1.000 22.43083  ? 17  SER H CA   1 
ATOM   215  C C    . SER A 1 17  ? 2.75475   -24.83087 17.41561  1.000 21.82514  ? 17  SER H C    1 
ATOM   216  O O    . SER A 1 17  ? 3.69265   -24.89634 16.61623  1.000 18.68505  ? 17  SER H O    1 
ATOM   217  C CB   . SER A 1 17  ? 1.50958   -26.88829 18.08970  1.000 28.29165  ? 17  SER H CB   1 
ATOM   218  O OG   . SER A 1 17  ? 0.35919   -27.69200 17.87251  1.000 35.54158  ? 17  SER H OG   1 
ATOM   219  H H    . SER A 1 17  ? 2.00758   -26.35446 15.46631  1.000 24.12903  ? 17  SER H H    1 
ATOM   220  H HA   . SER A 1 17  ? 0.72975   -25.07375 17.48723  1.000 26.92383  ? 17  SER H HA   1 
ATOM   221  H HB2  . SER A 1 17  ? 2.30074   -27.40462 17.86973  1.000 33.95681  ? 17  SER H HB2  1 
ATOM   222  H HB3  . SER A 1 17  ? 1.53611   -26.62153 19.02192  1.000 33.95681  ? 17  SER H HB3  1 
ATOM   223  H HG   . SER A 1 17  ? -0.33262  -27.26828 18.09038  1.000 42.65672  ? 17  SER H HG   1 
ATOM   224  N N    . LEU A 1 18  ? 2.76918   -24.05280 18.49174  1.000 18.55415  ? 18  LEU H N    1 
ATOM   225  C CA   . LEU A 1 18  ? 3.97427   -23.39978 18.96727  1.000 16.07743  ? 18  LEU H CA   1 
ATOM   226  C C    . LEU A 1 18  ? 4.28796   -23.89189 20.37171  1.000 18.48547  ? 18  LEU H C    1 
ATOM   227  O O    . LEU A 1 18  ? 3.38510   -24.20384 21.16315  1.000 17.99134  ? 18  LEU H O    1 
ATOM   228  C CB   . LEU A 1 18  ? 3.85001   -21.86504 18.96394  1.000 23.21808  ? 18  LEU H CB   1 
ATOM   229  C CG   . LEU A 1 18  ? 2.85614   -21.16564 19.89662  1.000 20.51618  ? 18  LEU H CG   1 
ATOM   230  C CD1  . LEU A 1 18  ? 3.28486   -21.19550 21.36870  1.000 19.54855  ? 18  LEU H CD1  1 
ATOM   231  C CD2  . LEU A 1 18  ? 2.63893   -19.72712 19.43671  1.000 21.72856  ? 18  LEU H CD2  1 
ATOM   232  H H    . LEU A 1 18  ? 2.07527   -23.88640 18.97173  1.000 22.27181  ? 18  LEU H H    1 
ATOM   233  H HA   . LEU A 1 18  ? 4.71329   -23.62628 18.38122  1.000 19.29975  ? 18  LEU H HA   1 
ATOM   234  H HB2  . LEU A 1 18  ? 4.72382   -21.50795 19.18718  1.000 27.86853  ? 18  LEU H HB2  1 
ATOM   235  H HB3  . LEU A 1 18  ? 3.60387   -21.60107 18.06359  1.000 27.86853  ? 18  LEU H HB3  1 
ATOM   236  H HG   . LEU A 1 18  ? 2.01912   -21.65369 19.85071  1.000 24.62626  ? 18  LEU H HG   1 
ATOM   237  H HD11 . LEU A 1 18  ? 3.00049   -20.37304 21.79719  1.000 23.46510  ? 18  LEU H HD11 1 
ATOM   238  H HD12 . LEU A 1 18  ? 2.86853   -21.95609 21.80351  1.000 23.46510  ? 18  LEU H HD12 1 
ATOM   239  H HD13 . LEU A 1 18  ? 4.25043   -21.27580 21.41485  1.000 23.46510  ? 18  LEU H HD13 1 
ATOM   240  H HD21 . LEU A 1 18  ? 1.99034   -19.30347 20.02044  1.000 26.08111  ? 18  LEU H HD21 1 
ATOM   241  H HD22 . LEU A 1 18  ? 3.48300   -19.25107 19.47939  1.000 26.08111  ? 18  LEU H HD22 1 
ATOM   242  H HD23 . LEU A 1 18  ? 2.30859   -19.73362 18.52471  1.000 26.08111  ? 18  LEU H HD23 1 
ATOM   243  N N    . ARG A 1 19  ? 5.58866   -23.95999 20.65205  1.000 20.47685  ? 19  ARG H N    1 
ATOM   244  C CA   . ARG A 1 19  ? 6.11928   -24.27431 21.97397  1.000 18.29543  ? 19  ARG H CA   1 
ATOM   245  C C    . ARG A 1 19  ? 7.25378   -23.29382 22.23929  1.000 20.18892  ? 19  ARG H C    1 
ATOM   246  O O    . ARG A 1 19  ? 8.26617   -23.30633 21.53532  1.000 18.27730  ? 19  ARG H O    1 
ATOM   247  C CB   . ARG A 1 19  ? 6.60885   -25.71884 22.05221  1.000 23.69996  ? 19  ARG H CB   1 
ATOM   248  C CG   . ARG A 1 19  ? 7.03078   -26.13728 23.45043  1.000 27.23377  ? 19  ARG H CG   1 
ATOM   249  C CD   . ARG A 1 19  ? 7.90315   -27.38772 23.44047  1.000 31.72062  ? 19  ARG H CD   1 
ATOM   250  N NE   . ARG A 1 19  ? 8.90323   -27.33055 24.49980  1.000 49.05423  ? 19  ARG H NE   1 
ATOM   251  C CZ   . ARG A 1 19  ? 9.95140   -26.51604 24.49304  1.000 59.05076  ? 19  ARG H CZ   1 
ATOM   252  N NH1  . ARG A 1 19  ? 10.16767  -25.67365 23.49363  1.000 50.10572  ? 19  ARG H NH1  1 
ATOM   253  N NH2  . ARG A 1 19  ? 10.79907  -26.54102 25.51771  1.000 62.21571  ? 19  ARG H NH2  1 
ATOM   254  H H    . ARG A 1 19  ? 6.20613   -23.82249 20.06944  1.000 24.57905  ? 19  ARG H H    1 
ATOM   255  H HA   . ARG A 1 19  ? 5.43116   -24.15841 22.64773  1.000 21.96135  ? 19  ARG H HA   1 
ATOM   256  H HB2  . ARG A 1 19  ? 5.89258   -26.30818 21.76841  1.000 28.44678  ? 19  ARG H HB2  1 
ATOM   257  H HB3  . ARG A 1 19  ? 7.37514   -25.82208 21.46651  1.000 28.44678  ? 19  ARG H HB3  1 
ATOM   258  H HG2  . ARG A 1 19  ? 7.53856   -25.41847 23.85830  1.000 32.68736  ? 19  ARG H HG2  1 
ATOM   259  H HG3  . ARG A 1 19  ? 6.23944   -26.32576 23.97879  1.000 32.68736  ? 19  ARG H HG3  1 
ATOM   260  H HD2  . ARG A 1 19  ? 7.34834   -28.17057 23.58276  1.000 38.07158  ? 19  ARG H HD2  1 
ATOM   261  H HD3  . ARG A 1 19  ? 8.36107   -27.45611 22.58810  1.000 38.07158  ? 19  ARG H HD3  1 
ATOM   262  H HE   . ARG A 1 19  ? 8.80798   -27.85831 25.17211  1.000 58.87191  ? 19  ARG H HE   1 
ATOM   263  H HH11 . ARG A 1 19  ? 9.62252   -25.64586 22.82907  1.000 60.13370  ? 19  ARG H HH11 1 
ATOM   264  H HH12 . ARG A 1 19  ? 10.85320  -25.15462 23.50944  1.000 60.13370  ? 19  ARG H HH12 1 
ATOM   265  H HH21 . ARG A 1 19  ? 10.66466  -27.08040 26.17392  1.000 74.66568  ? 19  ARG H HH21 1 
ATOM   266  H HH22 . ARG A 1 19  ? 11.48156  -26.01779 25.52403  1.000 74.66568  ? 19  ARG H HH22 1 
ATOM   267  N N    . LEU A 1 20  ? 7.06788   -22.42912 23.22651  1.000 17.85957  ? 20  LEU H N    1 
ATOM   268  C CA   . LEU A 1 20  ? 8.06207   -21.44315 23.62038  1.000 16.70564  ? 20  LEU H CA   1 
ATOM   269  C C    . LEU A 1 20  ? 8.43963   -21.69940 25.06862  1.000 17.53711  ? 20  LEU H C    1 
ATOM   270  O O    . LEU A 1 20  ? 7.58137   -22.03210 25.88716  1.000 19.22445  ? 20  LEU H O    1 
ATOM   271  C CB   . LEU A 1 20  ? 7.53013   -20.02403 23.46827  1.000 16.94067  ? 20  LEU H CB   1 
ATOM   272  C CG   . LEU A 1 20  ? 6.93941   -19.67026 22.10418  1.000 23.77114  ? 20  LEU H CG   1 
ATOM   273  C CD1  . LEU A 1 20  ? 6.30125   -18.29275 22.17447  1.000 22.18859  ? 20  LEU H CD1  1 
ATOM   274  C CD2  . LEU A 1 20  ? 8.00069   -19.73235 21.02087  1.000 24.16863  ? 20  LEU H CD2  1 
ATOM   275  H H    . LEU A 1 20  ? 6.34977   -22.39336 23.69836  1.000 21.43832  ? 20  LEU H H    1 
ATOM   276  H HA   . LEU A 1 20  ? 8.85168   -21.52233 23.06258  1.000 20.05360  ? 20  LEU H HA   1 
ATOM   277  H HB2  . LEU A 1 20  ? 6.83043   -19.89155 24.12688  1.000 20.33564  ? 20  LEU H HB2  1 
ATOM   278  H HB3  . LEU A 1 20  ? 8.26132   -19.40818 23.63259  1.000 20.33564  ? 20  LEU H HB3  1 
ATOM   279  H HG   . LEU A 1 20  ? 6.25547   -20.31515 21.86493  1.000 28.53220  ? 20  LEU H HG   1 
ATOM   280  H HD11 . LEU A 1 20  ? 5.94310   -18.06574 21.30206  1.000 26.63314  ? 20  LEU H HD11 1 
ATOM   281  H HD12 . LEU A 1 20  ? 5.58752   -18.30849 22.83116  1.000 26.63314  ? 20  LEU H HD12 1 
ATOM   282  H HD13 . LEU A 1 20  ? 6.97531   -17.64530 22.43400  1.000 26.63314  ? 20  LEU H HD13 1 
ATOM   283  H HD21 . LEU A 1 20  ? 7.61476   -19.43214 20.18312  1.000 29.00919  ? 20  LEU H HD21 1 
ATOM   284  H HD22 . LEU A 1 20  ? 8.74012   -19.15599 21.26977  1.000 29.00919  ? 20  LEU H HD22 1 
ATOM   285  H HD23 . LEU A 1 20  ? 8.30963   -20.64768 20.93353  1.000 29.00919  ? 20  LEU H HD23 1 
ATOM   286  N N    . SER A 1 21  ? 9.72164   -21.56248 25.38047  1.000 16.53725  ? 21  SER H N    1 
ATOM   287  C CA   . SER A 1 21  ? 10.20273  -21.75232 26.73970  1.000 21.68760  ? 21  SER H CA   1 
ATOM   288  C C    . SER A 1 21  ? 10.99690  -20.53025 27.16759  1.000 23.14395  ? 21  SER H C    1 
ATOM   289  O O    . SER A 1 21  ? 11.57007  -19.82485 26.34022  1.000 24.47057  ? 21  SER H O    1 
ATOM   290  C CB   . SER A 1 21  ? 11.07320  -23.00763 26.86139  1.000 26.70628  ? 21  SER H CB   1 
ATOM   291  O OG   . SER A 1 21  ? 10.28607  -24.18325 26.74657  1.000 33.98917  ? 21  SER H OG   1 
ATOM   292  H H    . SER A 1 21  ? 10.33720  -21.35801 24.81578  1.000 19.85153  ? 21  SER H H    1 
ATOM   293  H HA   . SER A 1 21  ? 9.44790   -21.85268 27.34058  1.000 26.03195  ? 21  SER H HA   1 
ATOM   294  H HB2  . SER A 1 21  ? 11.73628  -23.00156 26.15345  1.000 32.05437  ? 21  SER H HB2  1 
ATOM   295  H HB3  . SER A 1 21  ? 11.51165  -23.00481 27.72664  1.000 32.05437  ? 21  SER H HB3  1 
ATOM   296  H HG   . SER A 1 21  ? 9.71162   -24.20534 27.35903  1.000 40.79384  ? 21  SER H HG   1 
ATOM   297  N N    . CYS A 1 22  ? 11.00255  -20.27440 28.46928  1.000 20.70668  ? 22  CYS H N    1 
ATOM   298  C CA   . CYS A 1 22  ? 11.83778  -19.24607 29.07015  1.000 19.80830  ? 22  CYS H CA   1 
ATOM   299  C C    . CYS A 1 22  ? 12.57356  -19.86507 30.24367  1.000 19.08078  ? 22  CYS H C    1 
ATOM   300  O O    . CYS A 1 22  ? 11.95578  -20.50967 31.09831  1.000 17.46453  ? 22  CYS H O    1 
ATOM   301  C CB   . CYS A 1 22  ? 11.01938  -18.03465 29.53014  1.000 18.32815  ? 22  CYS H CB   1 
ATOM   302  S SG   . CYS A 1 22  ? 10.48292  -17.01101 28.15132  1.000 31.45422  ? 22  CYS H SG   1 
ATOM   303  H H    . CYS A 1 22  ? 10.51691  -20.69577 29.04042  1.000 24.85485  ? 22  CYS H H    1 
ATOM   304  H HA   . CYS A 1 22  ? 12.48279  -18.92675 28.41984  1.000 23.77680  ? 22  CYS H HA   1 
ATOM   305  H HB2  . CYS A 1 22  ? 10.23043  -18.34499 30.00146  1.000 22.00062  ? 22  CYS H HB2  1 
ATOM   306  H HB3  . CYS A 1 22  ? 11.56393  -17.48854 30.11847  1.000 22.00062  ? 22  CYS H HB3  1 
ATOM   307  N N    . THR A 1 23  ? 13.88733  -19.67551 30.26851  1.000 20.38378  ? 23  THR H N    1 
ATOM   308  C CA   . THR A 1 23  ? 14.74351  -20.18331 31.33104  1.000 21.18886  ? 23  THR H CA   1 
ATOM   309  C C    . THR A 1 23  ? 15.11284  -19.05090 32.27963  1.000 19.12852  ? 23  THR H C    1 
ATOM   310  O O    . THR A 1 23  ? 15.61072  -18.00650 31.84466  1.000 21.79431  ? 23  THR H O    1 
ATOM   311  C CB   . THR A 1 23  ? 16.01187  -20.80799 30.74960  1.000 25.72806  ? 23  THR H CB   1 
ATOM   312  O OG1  . THR A 1 23  ? 15.65385  -21.82677 29.81312  1.000 21.40559  ? 23  THR H OG1  1 
ATOM   313  C CG2  . THR A 1 23  ? 16.88049  -21.40492 31.85272  1.000 24.66796  ? 23  THR H CG2  1 
ATOM   314  H H    . THR A 1 23  ? 14.31792  -19.24291 29.66267  1.000 24.46737  ? 23  THR H H    1 
ATOM   315  H HA   . THR A 1 23  ? 14.26441  -20.86080 31.83340  1.000 25.43346  ? 23  THR H HA   1 
ATOM   316  H HB   . THR A 1 23  ? 16.53209  -20.12388 30.29987  1.000 30.88051  ? 23  THR H HB   1 
ATOM   317  H HG1  . THR A 1 23  ? 15.23096  -21.49017 29.17011  1.000 25.69354  ? 23  THR H HG1  1 
ATOM   318  H HG21 . THR A 1 23  ? 17.60475  -21.91917 31.46299  1.000 29.60839  ? 23  THR H HG21 1 
ATOM   319  H HG22 . THR A 1 23  ? 17.25574  -20.69683 32.39925  1.000 29.60839  ? 23  THR H HG22 1 
ATOM   320  H HG23 . THR A 1 23  ? 16.34761  -21.98817 32.41555  1.000 29.60839  ? 23  THR H HG23 1 
ATOM   321  N N    . ALA A 1 24  ? 14.86671  -19.26718 33.56678  1.000 17.95420  ? 24  ALA H N    1 
ATOM   322  C CA   . ALA A 1 24  ? 15.20229  -18.30374 34.59649  1.000 19.88249  ? 24  ALA H CA   1 
ATOM   323  C C    . ALA A 1 24  ? 16.63908  -18.51127 35.04462  1.000 23.79685  ? 24  ALA H C    1 
ATOM   324  O O    . ALA A 1 24  ? 17.11045  -19.64660 35.15603  1.000 22.64168  ? 24  ALA H O    1 
ATOM   325  C CB   . ALA A 1 24  ? 14.26355  -18.43771 35.79673  1.000 19.37443  ? 24  ALA H CB   1 
ATOM   326  H H    . ALA A 1 24  ? 14.49767  -19.98163 33.87169  1.000 21.55188  ? 24  ALA H H    1 
ATOM   327  H HA   . ALA A 1 24  ? 15.10916  -17.40599 34.24114  1.000 23.86582  ? 24  ALA H HA   1 
ATOM   328  H HB1  . ALA A 1 24  ? 14.53872  -17.81131 36.48433  1.000 23.25614  ? 24  ALA H HB1  1 
ATOM   329  H HB2  . ALA A 1 24  ? 13.35744  -18.23997 35.51257  1.000 23.25614  ? 24  ALA H HB2  1 
ATOM   330  H HB3  . ALA A 1 24  ? 14.31308  -19.34484 36.13667  1.000 23.25614  ? 24  ALA H HB3  1 
ATOM   331  N N    . SER A 1 25  ? 17.32972  -17.40069 35.28335  1.000 21.28836  ? 25  SER H N    1 
ATOM   332  C CA   . SER A 1 25  ? 18.63581  -17.38751 35.92231  1.000 27.32938  ? 25  SER H CA   1 
ATOM   333  C C    . SER A 1 25  ? 18.59915  -16.37128 37.05210  1.000 26.22906  ? 25  SER H C    1 
ATOM   334  O O    . SER A 1 25  ? 18.14250  -15.24048 36.85388  1.000 22.66440  ? 25  SER H O    1 
ATOM   335  C CB   . SER A 1 25  ? 19.73302  -17.03271 34.92317  1.000 26.62988  ? 25  SER H CB   1 
ATOM   336  O OG   . SER A 1 25  ? 19.71459  -17.92336 33.82146  1.000 32.45971  ? 25  SER H OG   1 
ATOM   337  H H    . SER A 1 25  ? 17.04983  -16.61451 35.07554  1.000 25.55287  ? 25  SER H H    1 
ATOM   338  H HA   . SER A 1 25  ? 18.83866  -18.26124 36.29157  1.000 32.80209  ? 25  SER H HA   1 
ATOM   339  H HB2  . SER A 1 25  ? 19.58800  -16.12905 34.60181  1.000 31.96268  ? 25  SER H HB2  1 
ATOM   340  H HB3  . SER A 1 25  ? 20.59457  -17.09355 35.36469  1.000 31.96268  ? 25  SER H HB3  1 
ATOM   341  H HG   . SER A 1 25  ? 20.31934  -17.71799 33.27585  1.000 38.95849  ? 25  SER H HG   1 
ATOM   342  N N    . GLY A 1 26  ? 19.06140  -16.77509 38.23425  1.000 22.75489  ? 26  GLY H N    1 
ATOM   343  C CA   . GLY A 1 26  ? 19.12459  -15.89551 39.38327  1.000 24.33678  ? 26  GLY H CA   1 
ATOM   344  C C    . GLY A 1 26  ? 17.97256  -16.01901 40.35597  1.000 23.39456  ? 26  GLY H C    1 
ATOM   345  O O    . GLY A 1 26  ? 18.00250  -15.36991 41.40718  1.000 24.38190  ? 26  GLY H O    1 
ATOM   346  H H    . GLY A 1 26  ? 19.34807  -17.57047 38.39174  1.000 27.31270  ? 26  GLY H H    1 
ATOM   347  H HA2  . GLY A 1 26  ? 19.94211  -16.08236 39.87076  1.000 29.21097  ? 26  GLY H HA2  1 
ATOM   348  H HA3  . GLY A 1 26  ? 19.14690  -14.97806 39.06915  1.000 29.21097  ? 26  GLY H HA3  1 
ATOM   349  N N    . PHE A 1 27  ? 16.96458  -16.82218 40.04005  1.000 21.29345  ? 27  PHE H N    1 
ATOM   350  C CA   . PHE A 1 27  ? 15.78321  -16.97288 40.87963  1.000 19.60412  ? 27  PHE H CA   1 
ATOM   351  C C    . PHE A 1 27  ? 15.12236  -18.28144 40.48001  1.000 22.80650  ? 27  PHE H C    1 
ATOM   352  O O    . PHE A 1 27  ? 15.47907  -18.88693 39.46901  1.000 26.13956  ? 27  PHE H O    1 
ATOM   353  C CB   . PHE A 1 27  ? 14.82999  -15.78084 40.72502  1.000 20.51374  ? 27  PHE H CB   1 
ATOM   354  C CG   . PHE A 1 27  ? 14.32361  -15.59076 39.32135  1.000 21.69989  ? 27  PHE H CG   1 
ATOM   355  C CD1  . PHE A 1 27  ? 15.07905  -14.90397 38.38595  1.000 21.87346  ? 27  PHE H CD1  1 
ATOM   356  C CD2  . PHE A 1 27  ? 13.10581  -16.11624 38.93200  1.000 21.23277  ? 27  PHE H CD2  1 
ATOM   357  C CE1  . PHE A 1 27  ? 14.62797  -14.74000 37.09445  1.000 22.10311  ? 27  PHE H CE1  1 
ATOM   358  C CE2  . PHE A 1 27  ? 12.65108  -15.94985 37.63890  1.000 18.64907  ? 27  PHE H CE2  1 
ATOM   359  C CZ   . PHE A 1 27  ? 13.41678  -15.26537 36.72132  1.000 17.57854  ? 27  PHE H CZ   1 
ATOM   360  H H    . PHE A 1 27  ? 16.93988  -17.30265 39.32720  1.000 25.55898  ? 27  PHE H H    1 
ATOM   361  H HA   . PHE A 1 27  ? 16.03369  -17.02005 41.81554  1.000 23.53178  ? 27  PHE H HA   1 
ATOM   362  H HB2  . PHE A 1 27  ? 14.06188  -15.91850 41.30117  1.000 24.62332  ? 27  PHE H HB2  1 
ATOM   363  H HB3  . PHE A 1 27  ? 15.29780  -14.97139 40.98355  1.000 24.62332  ? 27  PHE H HB3  1 
ATOM   364  H HD1  . PHE A 1 27  ? 15.90220  -14.54850 38.63285  1.000 26.25499  ? 27  PHE H HD1  1 
ATOM   365  H HD2  . PHE A 1 27  ? 12.58855  -16.58567 39.54598  1.000 25.48616  ? 27  PHE H HD2  1 
ATOM   366  H HE1  . PHE A 1 27  ? 15.14370  -14.27393 36.47662  1.000 26.53057  ? 27  PHE H HE1  1 
ATOM   367  H HE2  . PHE A 1 27  ? 11.82715  -16.30024 37.38739  1.000 22.38572  ? 27  PHE H HE2  1 
ATOM   368  H HZ   . PHE A 1 27  ? 13.11281  -15.15931 35.84882  1.000 21.10108  ? 27  PHE H HZ   1 
ATOM   369  N N    . SER A 1 28  ? 14.16421  -18.72232 41.28714  1.000 22.69507  ? 28  SER H N    1 
ATOM   370  C CA   . SER A 1 28  ? 13.48771  -19.98985 41.05137  1.000 24.37724  ? 28  SER H CA   1 
ATOM   371  C C    . SER A 1 28  ? 12.14368  -19.74736 40.38419  1.000 26.55577  ? 28  SER H C    1 
ATOM   372  O O    . SER A 1 28  ? 11.37354  -18.87844 40.80703  1.000 21.64272  ? 28  SER H O    1 
ATOM   373  C CB   . SER A 1 28  ? 13.29985  -20.77138 42.35035  1.000 27.19227  ? 28  SER H CB   1 
ATOM   374  O OG   . SER A 1 28  ? 14.54776  -21.25504 42.80818  1.000 26.07124  ? 28  SER H OG   1 
ATOM   375  H H    . SER A 1 28  ? 13.88696  -18.30059 41.98347  1.000 27.24092  ? 28  SER H H    1 
ATOM   376  H HA   . SER A 1 28  ? 14.03059  -20.52672 40.45308  1.000 29.25952  ? 28  SER H HA   1 
ATOM   377  H HB2  . SER A 1 28  ? 12.91827  -20.18574 43.02290  1.000 32.63756  ? 28  SER H HB2  1 
ATOM   378  H HB3  . SER A 1 28  ? 12.70662  -21.52159 42.18857  1.000 32.63756  ? 28  SER H HB3  1 
ATOM   379  H HG   . SER A 1 28  ? 15.06818  -20.61248 42.95608  1.000 31.29233  ? 28  SER H HG   1 
ATOM   380  N N    . ILE A 1 29  ? 11.86549  -20.53168 39.34879  1.000 23.46528  ? 29  ILE H N    1 
ATOM   381  C CA   . ILE A 1 29  ? 10.67463  -20.29632 38.55024  1.000 24.08778  ? 29  ILE H CA   1 
ATOM   382  C C    . ILE A 1 29  ? 9.40565   -20.53811 39.35973  1.000 27.16610  ? 29  ILE H C    1 
ATOM   383  O O    . ILE A 1 29  ? 8.36478   -19.94099 39.06961  1.000 27.59275  ? 29  ILE H O    1 
ATOM   384  C CB   . ILE A 1 29  ? 10.74575  -21.17112 37.28598  1.000 22.54679  ? 29  ILE H CB   1 
ATOM   385  C CG1  . ILE A 1 29  ? 9.79529   -20.63498 36.21899  1.000 23.31249  ? 29  ILE H CG1  1 
ATOM   386  C CG2  . ILE A 1 29  ? 10.44610  -22.62897 37.61204  1.000 23.56738  ? 29  ILE H CG2  1 
ATOM   387  C CD1  . ILE A 1 29  ? 10.27697  -19.34434 35.59031  1.000 23.73087  ? 29  ILE H CD1  1 
ATOM   388  H H    . ILE A 1 29  ? 12.34462  -21.19805 39.09190  1.000 28.16517  ? 29  ILE H H    1 
ATOM   389  H HA   . ILE A 1 29  ? 10.64647  -19.36539 38.27915  1.000 28.91218  ? 29  ILE H HA   1 
ATOM   390  H HB   . ILE A 1 29  ? 11.64970  -21.12970 36.93662  1.000 27.06298  ? 29  ILE H HB   1 
ATOM   391  H HG12 . ILE A 1 29  ? 9.70773   -21.29622 35.51472  1.000 27.98182  ? 29  ILE H HG12 1 
ATOM   392  H HG13 . ILE A 1 29  ? 8.93051   -20.46561 36.62442  1.000 27.98182  ? 29  ILE H HG13 1 
ATOM   393  H HG21 . ILE A 1 29  ? 10.71230  -23.18176 36.86074  1.000 28.28769  ? 29  ILE H HG21 1 
ATOM   394  H HG22 . ILE A 1 29  ? 10.94484  -22.88445 38.40380  1.000 28.28769  ? 29  ILE H HG22 1 
ATOM   395  H HG23 . ILE A 1 29  ? 9.49483   -22.72719 37.77432  1.000 28.28769  ? 29  ILE H HG23 1 
ATOM   396  H HD11 . ILE A 1 29  ? 9.71649   -19.13679 34.82632  1.000 28.48387  ? 29  ILE H HD11 1 
ATOM   397  H HD12 . ILE A 1 29  ? 10.21860  -18.63239 36.24653  1.000 28.48387  ? 29  ILE H HD12 1 
ATOM   398  H HD13 . ILE A 1 29  ? 11.19719  -19.45636 35.30475  1.000 28.48387  ? 29  ILE H HD13 1 
ATOM   399  N N    . ASP A 1 30  ? 9.46240   -21.37577 40.39599  1.000 24.80323  ? 30  ASP H N    1 
ATOM   400  C CA   . ASP A 1 30  ? 8.27761   -21.69951 41.17931  1.000 27.47994  ? 30  ASP H CA   1 
ATOM   401  C C    . ASP A 1 30  ? 8.07027   -20.76767 42.36873  1.000 26.58251  ? 30  ASP H C    1 
ATOM   402  O O    . ASP A 1 30  ? 7.09736   -20.94122 43.10686  1.000 25.70027  ? 30  ASP H O    1 
ATOM   403  C CB   . ASP A 1 30  ? 8.34649   -23.15184 41.67038  1.000 33.91889  ? 30  ASP H CB   1 
ATOM   404  C CG   . ASP A 1 30  ? 9.62984   -23.45822 42.41193  1.000 35.15314  ? 30  ASP H CG   1 
ATOM   405  O OD1  . ASP A 1 30  ? 9.91121   -22.78260 43.42257  1.000 44.46680  ? 30  ASP H OD1  1 
ATOM   406  O OD2  . ASP A 1 30  ? 10.35521  -24.38287 41.98682  1.000 54.28631  ? 30  ASP H OD2  1 
ATOM   407  H H    . ASP A 1 30  ? 10.17936  -21.76859 40.66293  1.000 29.77072  ? 30  ASP H H    1 
ATOM   408  H HA   . ASP A 1 30  ? 7.50144   -21.61651 40.60348  1.000 32.98276  ? 30  ASP H HA   1 
ATOM   409  H HB2  . ASP A 1 30  ? 7.60480   -23.31732 42.27321  1.000 40.70950  ? 30  ASP H HB2  1 
ATOM   410  H HB3  . ASP A 1 30  ? 8.29209   -23.74690 40.90628  1.000 40.70950  ? 30  ASP H HB3  1 
ATOM   411  N N    . SER A 1 31  ? 8.95098   -19.78582 42.56642  1.000 23.03642  ? 31  SER H N    1 
ATOM   412  C CA   . SER A 1 31  ? 8.76431   -18.79885 43.61970  1.000 24.54393  ? 31  SER H CA   1 
ATOM   413  C C    . SER A 1 31  ? 7.79654   -17.68573 43.23480  1.000 25.11825  ? 31  SER H C    1 
ATOM   414  O O    . SER A 1 31  ? 7.32672   -16.96573 44.12181  1.000 20.86258  ? 31  SER H O    1 
ATOM   415  C CB   . SER A 1 31  ? 10.11164  -18.17505 43.99719  1.000 24.66142  ? 31  SER H CB   1 
ATOM   416  O OG   . SER A 1 31  ? 10.99876  -19.15032 44.51247  1.000 39.52896  ? 31  SER H OG   1 
ATOM   417  H H    . SER A 1 31  ? 9.66532   -19.67199 42.10128  1.000 27.65053  ? 31  SER H H    1 
ATOM   418  H HA   . SER A 1 31  ? 8.40279   -19.25288 44.39691  1.000 29.45955  ? 31  SER H HA   1 
ATOM   419  H HB2  . SER A 1 31  ? 10.50684  -17.77701 43.20581  1.000 29.60054  ? 31  SER H HB2  1 
ATOM   420  H HB3  . SER A 1 31  ? 9.96509   -17.49469 44.67286  1.000 29.60054  ? 31  SER H HB3  1 
ATOM   421  H HG   . SER A 1 31  ? 11.73641  -18.79609 44.70219  1.000 47.44159  ? 31  SER H HG   1 
ATOM   422  N N    . TYR A 1 32  ? 7.48206   -17.52944 41.94975  1.000 21.64049  ? 32  TYR H N    1 
ATOM   423  C CA   . TYR A 1 32  ? 6.70360   -16.39093 41.48349  1.000 23.11440  ? 32  TYR H CA   1 
ATOM   424  C C    . TYR A 1 32  ? 5.69609   -16.83644 40.43659  1.000 22.42263  ? 32  TYR H C    1 
ATOM   425  O O    . TYR A 1 32  ? 5.81781   -17.91173 39.84540  1.000 19.72058  ? 32  TYR H O    1 
ATOM   426  C CB   . TYR A 1 32  ? 7.59965   -15.30991 40.87294  1.000 18.13867  ? 32  TYR H CB   1 
ATOM   427  C CG   . TYR A 1 32  ? 8.70417   -14.84869 41.78281  1.000 20.97221  ? 32  TYR H CG   1 
ATOM   428  C CD1  . TYR A 1 32  ? 8.43520   -14.00960 42.85349  1.000 22.11918  ? 32  TYR H CD1  1 
ATOM   429  C CD2  . TYR A 1 32  ? 10.01727  -15.24054 41.56938  1.000 22.38011  ? 32  TYR H CD2  1 
ATOM   430  C CE1  . TYR A 1 32  ? 9.44258   -13.57566 43.69553  1.000 26.55168  ? 32  TYR H CE1  1 
ATOM   431  C CE2  . TYR A 1 32  ? 11.03817  -14.81106 42.41000  1.000 27.74911  ? 32  TYR H CE2  1 
ATOM   432  C CZ   . TYR A 1 32  ? 10.74175  -13.97883 43.47343  1.000 31.98729  ? 32  TYR H CZ   1 
ATOM   433  O OH   . TYR A 1 32  ? 11.73899  -13.53506 44.31861  1.000 33.75068  ? 32  TYR H OH   1 
ATOM   434  H H    . TYR A 1 32  ? 7.71128   -18.07536 41.32603  1.000 25.97542  ? 32  TYR H H    1 
ATOM   435  H HA   . TYR A 1 32  ? 6.21959   -16.02460 42.24009  1.000 27.74412  ? 32  TYR H HA   1 
ATOM   436  H HB2  . TYR A 1 32  ? 8.00855   -15.66297 40.06731  1.000 21.77324  ? 32  TYR H HB2  1 
ATOM   437  H HB3  . TYR A 1 32  ? 7.05322   -14.53815 40.65683  1.000 21.77324  ? 32  TYR H HB3  1 
ATOM   438  H HD1  . TYR A 1 32  ? 7.56072   -13.73344 43.00820  1.000 26.54986  ? 32  TYR H HD1  1 
ATOM   439  H HD2  . TYR A 1 32  ? 10.21799  -15.79895 40.85328  1.000 26.86296  ? 32  TYR H HD2  1 
ATOM   440  H HE1  . TYR A 1 32  ? 9.24412   -13.01360 44.40939  1.000 31.86884  ? 32  TYR H HE1  1 
ATOM   441  H HE2  . TYR A 1 32  ? 11.91476  -15.08188 42.25787  1.000 33.30577  ? 32  TYR H HE2  1 
ATOM   442  H HH   . TYR A 1 32  ? 12.48000  -13.84965 44.07873  1.000 40.50764  ? 32  TYR H HH   1 
ATOM   443  N N    . GLY A 1 33  ? 4.70038   -15.98274 40.20491  1.000 17.18641  ? 33  GLY H N    1 
ATOM   444  C CA   . GLY A 1 33  ? 3.76659   -16.18611 39.11084  1.000 16.45841  ? 33  GLY H CA   1 
ATOM   445  C C    . GLY A 1 33  ? 4.26835   -15.53353 37.83186  1.000 16.60822  ? 33  GLY H C    1 
ATOM   446  O O    . GLY A 1 33  ? 4.85314   -14.45014 37.85708  1.000 16.04192  ? 33  GLY H O    1 
ATOM   447  H H    . GLY A 1 33  ? 4.54721   -15.27659 40.67128  1.000 20.63052  ? 33  GLY H H    1 
ATOM   448  H HA2  . GLY A 1 33  ? 3.65351   -17.13616 38.95108  1.000 19.75692  ? 33  GLY H HA2  1 
ATOM   449  H HA3  . GLY A 1 33  ? 2.90682   -15.79987 39.33997  1.000 19.75692  ? 33  GLY H HA3  1 
ATOM   450  N N    . PHE A 1 34  ? 4.03400   -16.21437 36.70729  1.000 14.97400  ? 34  PHE H N    1 
ATOM   451  C CA   . PHE A 1 34  ? 4.52912   -15.76541 35.41020  1.000 17.12364  ? 34  PHE H CA   1 
ATOM   452  C C    . PHE A 1 34  ? 3.41037   -15.75687 34.38567  1.000 13.64298  ? 34  PHE H C    1 
ATOM   453  O O    . PHE A 1 34  ? 2.59454   -16.67827 34.33867  1.000 11.97007  ? 34  PHE H O    1 
ATOM   454  C CB   . PHE A 1 34  ? 5.67210   -16.64690 34.91458  1.000 15.88884  ? 34  PHE H CB   1 
ATOM   455  C CG   . PHE A 1 34  ? 6.94485   -16.41283 35.65010  1.000 17.63343  ? 34  PHE H CG   1 
ATOM   456  C CD1  . PHE A 1 34  ? 7.82620   -15.43297 35.23068  1.000 17.44288  ? 34  PHE H CD1  1 
ATOM   457  C CD2  . PHE A 1 34  ? 7.23518   -17.12842 36.79501  1.000 21.09751  ? 34  PHE H CD2  1 
ATOM   458  C CE1  . PHE A 1 34  ? 8.98840   -15.18995 35.92973  1.000 21.68267  ? 34  PHE H CE1  1 
ATOM   459  C CE2  . PHE A 1 34  ? 8.39736   -16.89085 37.49331  1.000 22.73407  ? 34  PHE H CE2  1 
ATOM   460  C CZ   . PHE A 1 34  ? 9.27433   -15.91953 37.05763  1.000 23.32731  ? 34  PHE H CZ   1 
ATOM   461  H H    . PHE A 1 34  ? 3.58522   -16.94720 36.67327  1.000 17.97564  ? 34  PHE H H    1 
ATOM   462  H HA   . PHE A 1 34  ? 4.85385   -14.85580 35.50001  1.000 20.55520  ? 34  PHE H HA   1 
ATOM   463  H HB2  . PHE A 1 34  ? 5.42551   -17.57779 35.03098  1.000 19.07344  ? 34  PHE H HB2  1 
ATOM   464  H HB3  . PHE A 1 34  ? 5.82977   -16.46035 33.97583  1.000 19.07344  ? 34  PHE H HB3  1 
ATOM   465  H HD1  . PHE A 1 34  ? 7.63272   -14.93380 34.47022  1.000 20.93829  ? 34  PHE H HD1  1 
ATOM   466  H HD2  . PHE A 1 34  ? 6.64033   -17.77645 37.09685  1.000 25.32385  ? 34  PHE H HD2  1 
ATOM   467  H HE1  . PHE A 1 34  ? 9.57839   -14.53280 35.63822  1.000 26.02604  ? 34  PHE H HE1  1 
ATOM   468  H HE2  . PHE A 1 34  ? 8.59088   -17.38435 38.25745  1.000 27.28772  ? 34  PHE H HE2  1 
ATOM   469  H HZ   . PHE A 1 34  ? 10.06017  -15.75846 37.52817  1.000 27.99961  ? 34  PHE H HZ   1 
ATOM   470  N N    . SER A 1 35  ? 3.38704   -14.71000 33.56698  1.000 10.81856  ? 35  SER H N    1 
ATOM   471  C CA   . SER A 1 35  ? 2.43712   -14.53960 32.48979  1.000 13.11036  ? 35  SER H CA   1 
ATOM   472  C C    . SER A 1 35  ? 3.11652   -14.79230 31.15321  1.000 13.70591  ? 35  SER H C    1 
ATOM   473  O O    . SER A 1 35  ? 4.33912   -14.67159 31.00084  1.000 14.48523  ? 35  SER H O    1 
ATOM   474  C CB   . SER A 1 35  ? 1.85055   -13.11989 32.47777  1.000 15.98898  ? 35  SER H CB   1 
ATOM   475  O OG   . SER A 1 35  ? 1.17965   -12.81248 33.68556  1.000 19.16377  ? 35  SER H OG   1 
ATOM   476  H H    . SER A 1 35  ? 3.94235   -14.05580 33.62392  1.000 12.98910  ? 35  SER H H    1 
ATOM   477  H HA   . SER A 1 35  ? 1.71386   -15.17453 32.61092  1.000 15.73926  ? 35  SER H HA   1 
ATOM   478  H HB2  . SER A 1 35  ? 2.57383   -12.48559 32.35362  1.000 19.19361  ? 35  SER H HB2  1 
ATOM   479  H HB3  . SER A 1 35  ? 1.21898   -13.05052 31.74483  1.000 19.19361  ? 35  SER H HB3  1 
ATOM   480  H HG   . SER A 1 35  ? 0.52941   -13.33317 33.79359  1.000 23.00335  ? 35  SER H HG   1 
ATOM   481  N N    . TRP A 1 36  ? 2.29013   -15.13955 30.18477  1.000 11.72887  ? 36  TRP H N    1 
ATOM   482  C CA   . TRP A 1 36  ? 2.63683   -15.01698 28.78359  1.000 11.62700  ? 36  TRP H CA   1 
ATOM   483  C C    . TRP A 1 36  ? 1.73121   -13.95896 28.16266  1.000 11.15456  ? 36  TRP H C    1 
ATOM   484  O O    . TRP A 1 36  ? 0.52283   -13.90078 28.46028  1.000 14.68652  ? 36  TRP H O    1 
ATOM   485  C CB   . TRP A 1 36  ? 2.51171   -16.35098 28.05612  1.000 13.79058  ? 36  TRP H CB   1 
ATOM   486  C CG   . TRP A 1 36  ? 3.63061   -17.30763 28.34802  1.000 13.61818  ? 36  TRP H CG   1 
ATOM   487  C CD1  . TRP A 1 36  ? 3.69048   -18.21656 29.36985  1.000 15.82160  ? 36  TRP H CD1  1 
ATOM   488  C CD2  . TRP A 1 36  ? 4.85288   -17.45530 27.61110  1.000 13.00372  ? 36  TRP H CD2  1 
ATOM   489  N NE1  . TRP A 1 36  ? 4.86459   -18.92193 29.30442  1.000 15.35846  ? 36  TRP H NE1  1 
ATOM   490  C CE2  . TRP A 1 36  ? 5.59492   -18.47508 28.23440  1.000 11.96603  ? 36  TRP H CE2  1 
ATOM   491  C CE3  . TRP A 1 36  ? 5.38344   -16.83204 26.47808  1.000 12.16684  ? 36  TRP H CE3  1 
ATOM   492  C CZ2  . TRP A 1 36  ? 6.83997   -18.87842 27.77120  1.000 16.45816  ? 36  TRP H CZ2  1 
ATOM   493  C CZ3  . TRP A 1 36  ? 6.62235   -17.23845 26.01493  1.000 14.97211  ? 36  TRP H CZ3  1 
ATOM   494  C CH2  . TRP A 1 36  ? 7.33771   -18.24910 26.66209  1.000 17.19196  ? 36  TRP H CH2  1 
ATOM   495  H H    . TRP A 1 36  ? 1.50217   -15.45714 30.31840  1.000 14.08148  ? 36  TRP H H    1 
ATOM   496  H HA   . TRP A 1 36  ? 3.55968   -14.73679 28.67996  1.000 13.95923  ? 36  TRP H HA   1 
ATOM   497  H HB2  . TRP A 1 36  ? 1.68191   -16.77569 28.32435  1.000 16.55553  ? 36  TRP H HB2  1 
ATOM   498  H HB3  . TRP A 1 36  ? 2.50587   -16.18548 27.10036  1.000 16.55553  ? 36  TRP H HB3  1 
ATOM   499  H HD1  . TRP A 1 36  ? 3.03111   -18.33796 30.01436  1.000 18.99275  ? 36  TRP H HD1  1 
ATOM   500  H HE1  . TRP A 1 36  ? 5.10403   -19.54440 29.84737  1.000 18.43699  ? 36  TRP H HE1  1 
ATOM   501  H HE3  . TRP A 1 36  ? 4.91296   -16.15741 26.04401  1.000 14.60705  ? 36  TRP H HE3  1 
ATOM   502  H HZ2  . TRP A 1 36  ? 7.31840   -19.55158 28.19881  1.000 19.75663  ? 36  TRP H HZ2  1 
ATOM   503  H HZ3  . TRP A 1 36  ? 6.98467   -16.83236 25.26080  1.000 17.97337  ? 36  TRP H HZ3  1 
ATOM   504  H HH2  . TRP A 1 36  ? 8.17028   -18.49980 26.33214  1.000 20.63719  ? 36  TRP H HH2  1 
ATOM   505  N N    . VAL A 1 37  ? 2.36112   -13.13980 27.30905  1.000 10.72498  ? 37  VAL H N    1 
ATOM   506  C CA   . VAL A 1 37  ? 1.80612   -11.94554 26.67869  1.000 11.47340  ? 37  VAL H CA   1 
ATOM   507  C C    . VAL A 1 37  ? 2.20072   -11.98274 25.20811  1.000 14.41641  ? 37  VAL H C    1 
ATOM   508  O O    . VAL A 1 37  ? 3.23351   -12.55012 24.84661  1.000 14.99291  ? 37  VAL H O    1 
ATOM   509  C CB   . VAL A 1 37  ? 2.35523   -10.67149 27.36027  1.000 15.56875  ? 37  VAL H CB   1 
ATOM   510  C CG1  . VAL A 1 37  ? 1.87679   -9.42201  26.65723  1.000 21.15571  ? 37  VAL H CG1  1 
ATOM   511  C CG2  . VAL A 1 37  ? 1.97011   -10.65188 28.84555  1.000 15.97095  ? 37  VAL H CG2  1 
ATOM   512  H H    . VAL A 1 37  ? 3.17502   -13.26958 27.06344  1.000 12.87681  ? 37  VAL H H    1 
ATOM   513  H HA   . VAL A 1 37  ? 0.83807   -11.93755 26.73971  1.000 13.77492  ? 37  VAL H HA   1 
ATOM   514  H HB   . VAL A 1 37  ? 3.32323   -10.68154 27.29874  1.000 18.68934  ? 37  VAL H HB   1 
ATOM   515  H HG11 . VAL A 1 37  ? 2.08887   -8.65037  27.20539  1.000 25.39369  ? 37  VAL H HG11 1 
ATOM   516  H HG12 . VAL A 1 37  ? 2.32409   -9.35139  25.79942  1.000 25.39369  ? 37  VAL H HG12 1 
ATOM   517  H HG13 . VAL A 1 37  ? 0.91750   -9.48107  26.52619  1.000 25.39369  ? 37  VAL H HG13 1 
ATOM   518  H HG21 . VAL A 1 37  ? 2.30064   -9.83291  29.24671  1.000 19.17198  ? 37  VAL H HG21 1 
ATOM   519  H HG22 . VAL A 1 37  ? 1.00390   -10.69106 28.92180  1.000 19.17198  ? 37  VAL H HG22 1 
ATOM   520  H HG23 . VAL A 1 37  ? 2.36800   -11.41957 29.28513  1.000 19.17198  ? 37  VAL H HG23 1 
ATOM   521  N N    . ARG A 1 38  ? 1.37832   -11.39175 24.34161  1.000 11.59949  ? 38  ARG H N    1 
ATOM   522  C CA   . ARG A 1 38  ? 1.77745   -11.29410 22.94579  1.000 13.53556  ? 38  ARG H CA   1 
ATOM   523  C C    . ARG A 1 38  ? 1.43792   -9.92506  22.37688  1.000 10.72153  ? 38  ARG H C    1 
ATOM   524  O O    . ARG A 1 38  ? 0.65135   -9.16454  22.94176  1.000 14.81708  ? 38  ARG H O    1 
ATOM   525  C CB   . ARG A 1 38  ? 1.13316   -12.38116 22.08736  1.000 17.15888  ? 38  ARG H CB   1 
ATOM   526  C CG   . ARG A 1 38  ? -0.34655  -12.25843 21.92326  1.000 13.97837  ? 38  ARG H CG   1 
ATOM   527  C CD   . ARG A 1 38  ? -0.83897  -13.38538 21.03640  1.000 19.95778  ? 38  ARG H CD   1 
ATOM   528  N NE   . ARG A 1 38  ? -2.20008  -13.16583 20.57390  1.000 23.73934  ? 38  ARG H NE   1 
ATOM   529  C CZ   . ARG A 1 38  ? -2.93214  -14.08398 19.95666  1.000 26.74085  ? 38  ARG H CZ   1 
ATOM   530  N NH1  . ARG A 1 38  ? -2.46048  -15.29987 19.71934  1.000 17.80818  ? 38  ARG H NH1  1 
ATOM   531  N NH2  . ARG A 1 38  ? -4.17187  -13.77981 19.58484  1.000 21.86305  ? 38  ARG H NH2  1 
ATOM   532  H H    . ARG A 1 38  ? 0.61192   -11.05283 24.53493  1.000 13.92623  ? 38  ARG H H    1 
ATOM   533  H HA   . ARG A 1 38  ? 2.74157   -11.39386 22.90806  1.000 16.24951  ? 38  ARG H HA   1 
ATOM   534  H HB2  . ARG A 1 38  ? 1.52812   -12.34805 21.20203  1.000 20.59749  ? 38  ARG H HB2  1 
ATOM   535  H HB3  . ARG A 1 38  ? 1.31028   -13.24208 22.49767  1.000 20.59749  ? 38  ARG H HB3  1 
ATOM   536  H HG2  . ARG A 1 38  ? -0.78192  -12.32393 22.78759  1.000 16.78088  ? 38  ARG H HG2  1 
ATOM   537  H HG3  . ARG A 1 38  ? -0.56398  -11.41035 21.50568  1.000 16.78088  ? 38  ARG H HG3  1 
ATOM   538  H HD2  . ARG A 1 38  ? -0.26300  -13.45362 20.25890  1.000 23.95617  ? 38  ARG H HD2  1 
ATOM   539  H HD3  . ARG A 1 38  ? -0.82028  -14.21598 21.53705  1.000 23.95617  ? 38  ARG H HD3  1 
ATOM   540  H HE   . ARG A 1 38  ? -2.55226  -12.39294 20.70888  1.000 28.49404  ? 38  ARG H HE   1 
ATOM   541  H HH11 . ARG A 1 38  ? -1.66362  -15.50789 19.96702  1.000 21.37665  ? 38  ARG H HH11 1 
ATOM   542  H HH12 . ARG A 1 38  ? -2.95135  -15.88068 19.31771  1.000 21.37665  ? 38  ARG H HH12 1 
ATOM   543  H HH21 . ARG A 1 38  ? -4.48899  -12.99667 19.74525  1.000 26.24249  ? 38  ARG H HH21 1 
ATOM   544  H HH22 . ARG A 1 38  ? -4.65666  -14.36619 19.18393  1.000 26.24249  ? 38  ARG H HH22 1 
ATOM   545  N N    . GLN A 1 39  ? 2.06887   -9.62805  21.24195  1.000 12.87409  ? 39  GLN H N    1 
ATOM   546  C CA   . GLN A 1 39  ? 1.87252   -8.37516  20.52523  1.000 13.19913  ? 39  GLN H CA   1 
ATOM   547  C C    . GLN A 1 39  ? 1.82363   -8.68105  19.03418  1.000 13.73325  ? 39  GLN H C    1 
ATOM   548  O O    . GLN A 1 39  ? 2.84184   -9.05647  18.44815  1.000 14.89008  ? 39  GLN H O    1 
ATOM   549  C CB   . GLN A 1 39  ? 3.00022   -7.39714  20.84245  1.000 15.89555  ? 39  GLN H CB   1 
ATOM   550  C CG   . GLN A 1 39  ? 2.78771   -6.00493  20.30335  1.000 20.32175  ? 39  GLN H CG   1 
ATOM   551  C CD   . GLN A 1 39  ? 3.77732   -5.01534  20.89148  1.000 23.93803  ? 39  GLN H CD   1 
ATOM   552  O OE1  . GLN A 1 39  ? 4.96949   -5.30205  20.99950  1.000 23.65056  ? 39  GLN H OE1  1 
ATOM   553  N NE2  . GLN A 1 39  ? 3.28096   -3.85484  21.30076  1.000 22.39605  ? 39  GLN H NE2  1 
ATOM   554  H H    . GLN A 1 39  ? 2.63150   -10.15314 20.85811  1.000 15.45574  ? 39  GLN H H    1 
ATOM   555  H HA   . GLN A 1 39  ? 1.02550   -7.97757  20.78093  1.000 15.84579  ? 39  GLN H HA   1 
ATOM   556  H HB2  . GLN A 1 39  ? 3.08806   -7.32838  21.80601  1.000 19.08150  ? 39  GLN H HB2  1 
ATOM   557  H HB3  . GLN A 1 39  ? 3.82278   -7.73828  20.45784  1.000 19.08150  ? 39  GLN H HB3  1 
ATOM   558  H HG2  . GLN A 1 39  ? 2.90284   -6.01396  19.34025  1.000 24.39294  ? 39  GLN H HG2  1 
ATOM   559  H HG3  . GLN A 1 39  ? 1.89175   -5.70852  20.52761  1.000 24.39294  ? 39  GLN H HG3  1 
ATOM   560  H HE21 . GLN A 1 39  ? 2.43897   -3.69676  21.22546  1.000 26.88209  ? 39  GLN H HE21 1 
ATOM   561  H HE22 . GLN A 1 39  ? 3.80124   -3.26077  21.64133  1.000 26.88209  ? 39  GLN H HE22 1 
ATOM   562  N N    . ALA A 1 40  ? 0.64883   -8.54175  18.42923  1.000 17.85637  ? 40  ALA H N    1 
ATOM   563  C CA   . ALA A 1 40  ? 0.54557   -8.68905  16.98528  1.000 22.43561  ? 40  ALA H CA   1 
ATOM   564  C C    . ALA A 1 40  ? 1.19404   -7.48633  16.30142  1.000 29.48974  ? 40  ALA H C    1 
ATOM   565  O O    . ALA A 1 40  ? 1.26656   -6.39915  16.88223  1.000 22.71446  ? 40  ALA H O    1 
ATOM   566  C CB   . ALA A 1 40  ? -0.91178  -8.81214  16.55456  1.000 25.58302  ? 40  ALA H CB   1 
ATOM   567  H H    . ALA A 1 40  ? -0.09264  -8.36439  18.82718  1.000 21.43448  ? 40  ALA H H    1 
ATOM   568  H HA   . ALA A 1 40  ? 1.00322   -9.49603  16.70202  1.000 26.92956  ? 40  ALA H HA   1 
ATOM   569  H HB1  . ALA A 1 40  ? -0.95008  -8.88956  15.58841  1.000 30.70646  ? 40  ALA H HB1  1 
ATOM   570  H HB2  . ALA A 1 40  ? -1.29681  -9.60208  16.96522  1.000 30.70646  ? 40  ALA H HB2  1 
ATOM   571  H HB3  . ALA A 1 40  ? -1.39403  -8.02127  16.84240  1.000 30.70646  ? 40  ALA H HB3  1 
ATOM   572  N N    . PRO A 1 41  ? 1.67507   -7.65303  15.07236  1.000 35.39204  ? 41  PRO H N    1 
ATOM   573  C CA   . PRO A 1 41  ? 2.40357   -6.56075  14.41347  1.000 35.89716  ? 41  PRO H CA   1 
ATOM   574  C C    . PRO A 1 41  ? 1.61901   -5.25776  14.42987  1.000 29.65696  ? 41  PRO H C    1 
ATOM   575  O O    . PRO A 1 41  ? 0.45010   -5.20688  14.04043  1.000 32.17998  ? 41  PRO H O    1 
ATOM   576  C CB   . PRO A 1 41  ? 2.60540   -7.08745  12.98833  1.000 35.29563  ? 41  PRO H CB   1 
ATOM   577  C CG   . PRO A 1 41  ? 2.62370   -8.56183  13.14530  1.000 32.69402  ? 41  PRO H CG   1 
ATOM   578  C CD   . PRO A 1 41  ? 1.62327   -8.86087  14.22843  1.000 31.84700  ? 41  PRO H CD   1 
ATOM   579  H HA   . PRO A 1 41  ? 3.26305   -6.42053  14.84069  1.000 43.08342  ? 41  PRO H HA   1 
ATOM   580  H HB2  . PRO A 1 41  ? 1.87097   -6.80480  12.42121  1.000 42.36159  ? 41  PRO H HB2  1 
ATOM   581  H HB3  . PRO A 1 41  ? 3.44595   -6.76315  12.62887  1.000 42.36159  ? 41  PRO H HB3  1 
ATOM   582  H HG2  . PRO A 1 41  ? 2.36613   -8.98469  12.31119  1.000 39.23966  ? 41  PRO H HG2  1 
ATOM   583  H HG3  . PRO A 1 41  ? 3.51141   -8.85401  13.40511  1.000 39.23966  ? 41  PRO H HG3  1 
ATOM   584  H HD2  . PRO A 1 41  ? 0.73636   -8.98497  13.85576  1.000 38.22323  ? 41  PRO H HD2  1 
ATOM   585  H HD3  . PRO A 1 41  ? 1.88409   -9.64716  14.73304  1.000 38.22323  ? 41  PRO H HD3  1 
ATOM   586  N N    . GLY A 1 42  ? 2.27038   -4.20057  14.91595  1.000 38.16412  ? 42  GLY H N    1 
ATOM   587  C CA   . GLY A 1 42  ? 1.66640   -2.88528  14.98476  1.000 36.63756  ? 42  GLY H CA   1 
ATOM   588  C C    . GLY A 1 42  ? 0.49810   -2.74770  15.93357  1.000 39.31864  ? 42  GLY H C    1 
ATOM   589  O O    . GLY A 1 42  ? -0.21887  -1.74512  15.85939  1.000 45.38449  ? 42  GLY H O    1 
ATOM   590  H H    . GLY A 1 42  ? 3.07611   -4.22587  15.21553  1.000 45.80378  ? 42  GLY H H    1 
ATOM   591  H HA2  . GLY A 1 42  ? 2.34476   -2.25019  15.26296  1.000 43.97191  ? 42  GLY H HA2  1 
ATOM   592  H HA3  . GLY A 1 42  ? 1.35293   -2.64474  14.09889  1.000 43.97191  ? 42  GLY H HA3  1 
ATOM   593  N N    . LYS A 1 43  ? 0.28296   -3.71081  16.82636  1.000 33.30216  ? 43  LYS H N    1 
ATOM   594  C CA   . LYS A 1 43  ? -0.85954  -3.71133  17.73308  1.000 28.69125  ? 43  LYS H CA   1 
ATOM   595  C C    . LYS A 1 43  ? -0.37663  -3.64842  19.18079  1.000 22.17811  ? 43  LYS H C    1 
ATOM   596  O O    . LYS A 1 43  ? 0.82319   -3.62561  19.46263  1.000 27.88934  ? 43  LYS H O    1 
ATOM   597  C CB   . LYS A 1 43  ? -1.73205  -4.94924  17.50768  1.000 31.10255  ? 43  LYS H CB   1 
ATOM   598  C CG   . LYS A 1 43  ? -2.15218  -5.17441  16.05266  1.000 43.39202  ? 43  LYS H CG   1 
ATOM   599  C CD   . LYS A 1 43  ? -3.50769  -4.55841  15.74211  1.000 53.81288  ? 43  LYS H CD   1 
ATOM   600  C CE   . LYS A 1 43  ? -4.00784  -4.98462  14.36589  1.000 63.47180  ? 43  LYS H CE   1 
ATOM   601  N NZ   . LYS A 1 43  ? -5.21967  -5.85315  14.44665  1.000 64.75793  ? 43  LYS H NZ   1 
ATOM   602  H H    . LYS A 1 43  ? 0.79931   -4.39117  16.92688  1.000 39.96942  ? 43  LYS H H    1 
ATOM   603  H HA   . LYS A 1 43  ? -1.39423  -2.92120  17.55786  1.000 34.43634  ? 43  LYS H HA   1 
ATOM   604  H HB2  . LYS A 1 43  ? -1.23665  -5.73250  17.79400  1.000 37.32990  ? 43  LYS H HB2  1 
ATOM   605  H HB3  . LYS A 1 43  ? -2.54088  -4.85715  18.03513  1.000 37.32990  ? 43  LYS H HB3  1 
ATOM   606  H HG2  . LYS A 1 43  ? -1.49512  -4.76930  15.46524  1.000 52.07726  ? 43  LYS H HG2  1 
ATOM   607  H HG3  . LYS A 1 43  ? -2.20763  -6.12752  15.88116  1.000 52.07726  ? 43  LYS H HG3  1 
ATOM   608  H HD2  . LYS A 1 43  ? -4.15306  -4.84903  16.40538  1.000 64.58229  ? 43  LYS H HD2  1 
ATOM   609  H HD3  . LYS A 1 43  ? -3.43231  -3.59142  15.75396  1.000 64.58229  ? 43  LYS H HD3  1 
ATOM   610  H HE2  . LYS A 1 43  ? -4.23690  -4.19442  13.85208  1.000 76.17299  ? 43  LYS H HE2  1 
ATOM   611  H HE3  . LYS A 1 43  ? -3.30913  -5.48314  13.91402  1.000 76.17299  ? 43  LYS H HE3  1 
ATOM   612  H HZ1  . LYS A 1 43  ? -5.47528  -6.09580  13.62940  1.000 77.71635  ? 43  LYS H HZ1  1 
ATOM   613  H HZ2  . LYS A 1 43  ? -5.03938  -6.58382  14.92175  1.000 77.71635  ? 43  LYS H HZ2  1 
ATOM   614  H HZ3  . LYS A 1 43  ? -5.88550  -5.41104  14.83818  1.000 77.71635  ? 43  LYS H HZ3  1 
ATOM   615  N N    . GLY A 1 44  ? -1.33690  -3.62531  20.10581  1.000 22.18376  ? 44  GLY H N    1 
ATOM   616  C CA   . GLY A 1 44  ? -1.03548  -3.53417  21.51387  1.000 19.66736  ? 44  GLY H CA   1 
ATOM   617  C C    . GLY A 1 44  ? -0.71565  -4.88035  22.14263  1.000 21.50881  ? 44  GLY H C    1 
ATOM   618  O O    . GLY A 1 44  ? -0.73697  -5.93531  21.50814  1.000 21.67432  ? 44  GLY H O    1 
ATOM   619  H H    . GLY A 1 44  ? -2.17816  -3.66214  19.93111  1.000 26.62735  ? 44  GLY H H    1 
ATOM   620  H HA2  . GLY A 1 44  ? -0.26959  -2.95212  21.63847  1.000 23.60766  ? 44  GLY H HA2  1 
ATOM   621  H HA3  . GLY A 1 44  ? -1.79827  -3.15631  21.97892  1.000 23.60766  ? 44  GLY H HA3  1 
ATOM   622  N N    . LEU A 1 45  ? -0.40829  -4.82763  23.43256  1.000 20.21314  ? 45  LEU H N    1 
ATOM   623  C CA   . LEU A 1 45  ? -0.08396  -6.02855  24.18746  1.000 18.05866  ? 45  LEU H CA   1 
ATOM   624  C C    . LEU A 1 45  ? -1.35953  -6.74610  24.60869  1.000 16.00413  ? 45  LEU H C    1 
ATOM   625  O O    . LEU A 1 45  ? -2.38284  -6.12214  24.89951  1.000 19.86587  ? 45  LEU H O    1 
ATOM   626  C CB   . LEU A 1 45  ? 0.76361   -5.66356  25.40789  1.000 18.12033  ? 45  LEU H CB   1 
ATOM   627  C CG   . LEU A 1 45  ? 2.09066   -4.99126  25.05508  1.000 22.92780  ? 45  LEU H CG   1 
ATOM   628  C CD1  . LEU A 1 45  ? 2.69702   -4.27227  26.25523  1.000 18.60448  ? 45  LEU H CD1  1 
ATOM   629  C CD2  . LEU A 1 45  ? 3.06350   -6.02695  24.50967  1.000 21.41581  ? 45  LEU H CD2  1 
ATOM   630  H H    . LEU A 1 45  ? -0.38049  -4.10382  23.89616  1.000 24.26260  ? 45  LEU H H    1 
ATOM   631  H HA   . LEU A 1 45  ? 0.43196   -6.64247  23.64173  1.000 21.67722  ? 45  LEU H HA   1 
ATOM   632  H HB2  . LEU A 1 45  ? 0.25912   -5.05079  25.96547  1.000 21.75124  ? 45  LEU H HB2  1 
ATOM   633  H HB3  . LEU A 1 45  ? 0.96328   -6.47401  25.90207  1.000 21.75124  ? 45  LEU H HB3  1 
ATOM   634  H HG   . LEU A 1 45  ? 1.92614   -4.31980  24.37466  1.000 27.52019  ? 45  LEU H HG   1 
ATOM   635  H HD11 . LEU A 1 45  ? 3.53105   -3.85656  25.98603  1.000 22.33220  ? 45  LEU H HD11 1 
ATOM   636  H HD12 . LEU A 1 45  ? 2.07508   -3.59553  26.56526  1.000 22.33220  ? 45  LEU H HD12 1 
ATOM   637  H HD13 . LEU A 1 45  ? 2.86167   -4.91798  26.96010  1.000 22.33220  ? 45  LEU H HD13 1 
ATOM   638  H HD21 . LEU A 1 45  ? 3.86390   -5.57559  24.19895  1.000 25.70581  ? 45  LEU H HD21 1 
ATOM   639  H HD22 . LEU A 1 45  ? 3.28927   -6.65136  25.21681  1.000 25.70581  ? 45  LEU H HD22 1 
ATOM   640  H HD23 . LEU A 1 45  ? 2.64291   -6.49858  23.77376  1.000 25.70581  ? 45  LEU H HD23 1 
ATOM   641  N N    . GLU A 1 46  ? -1.28995  -8.07745  24.63503  1.000 15.02364  ? 46  GLU H N    1 
ATOM   642  C CA   . GLU A 1 46  ? -2.43351  -8.92467  24.94754  1.000 21.54274  ? 46  GLU H CA   1 
ATOM   643  C C    . GLU A 1 46  ? -1.98122  -10.01486 25.91024  1.000 16.61698  ? 46  GLU H C    1 
ATOM   644  O O    . GLU A 1 46  ? -1.03409  -10.74382 25.61523  1.000 16.02430  ? 46  GLU H O    1 
ATOM   645  C CB   . GLU A 1 46  ? -3.01077  -9.53697  23.66125  1.000 19.80248  ? 46  GLU H CB   1 
ATOM   646  C CG   . GLU A 1 46  ? -4.27835  -10.34830 23.83324  1.000 31.75987  ? 46  GLU H CG   1 
ATOM   647  C CD   . GLU A 1 46  ? -4.80193  -10.90895 22.51084  1.000 43.52460  ? 46  GLU H CD   1 
ATOM   648  O OE1  . GLU A 1 46  ? -4.00889  -11.02757 21.54275  1.000 31.85840  ? 46  GLU H OE1  1 
ATOM   649  O OE2  . GLU A 1 46  ? -6.01072  -11.23035 22.44047  1.000 47.32772  ? 46  GLU H OE2  1 
ATOM   650  H H    . GLU A 1 46  ? -0.57207  -8.52164  24.47087  1.000 18.03520  ? 46  GLU H H    1 
ATOM   651  H HA   . GLU A 1 46  ? -3.13184  -8.41128  25.38304  1.000 25.85812  ? 46  GLU H HA   1 
ATOM   652  H HB2  . GLU A 1 46  ? -3.21171  -8.81592  23.04432  1.000 23.76981  ? 46  GLU H HB2  1 
ATOM   653  H HB3  . GLU A 1 46  ? -2.34197  -10.12537 23.27732  1.000 23.76981  ? 46  GLU H HB3  1 
ATOM   654  H HG2  . GLU A 1 46  ? -4.09844  -11.09484 24.42587  1.000 38.11868  ? 46  GLU H HG2  1 
ATOM   655  H HG3  . GLU A 1 46  ? -4.96780  -9.78165  24.21334  1.000 38.11868  ? 46  GLU H HG3  1 
ATOM   656  N N    . HIS A 1 47  ? -2.65847  -10.12699 27.05212  1.000 16.44863  ? 47  HIS H N    1 
ATOM   657  C CA   . HIS A 1 47  ? -2.35133  -11.16145 28.03623  1.000 14.75958  ? 47  HIS H CA   1 
ATOM   658  C C    . HIS A 1 47  ? -2.89372  -12.51304 27.59194  1.000 17.32459  ? 47  HIS H C    1 
ATOM   659  O O    . HIS A 1 47  ? -4.07858  -12.64035 27.26877  1.000 20.00521  ? 47  HIS H O    1 
ATOM   660  C CB   . HIS A 1 47  ? -2.95813  -10.78456 29.38496  1.000 13.75759  ? 47  HIS H CB   1 
ATOM   661  C CG   . HIS A 1 47  ? -2.52702  -11.66028 30.51744  1.000 13.01739  ? 47  HIS H CG   1 
ATOM   662  N ND1  . HIS A 1 47  ? -3.39133  -12.50809 31.17175  1.000 13.66474  ? 47  HIS H ND1  1 
ATOM   663  C CD2  . HIS A 1 47  ? -1.32501  -11.80525 31.12398  1.000 12.42531  ? 47  HIS H CD2  1 
ATOM   664  C CE1  . HIS A 1 47  ? -2.74217  -13.13814 32.13608  1.000 16.17338  ? 47  HIS H CE1  1 
ATOM   665  N NE2  . HIS A 1 47  ? -1.48783  -12.72786 32.13014  1.000 14.53434  ? 47  HIS H NE2  1 
ATOM   666  H H    . HIS A 1 47  ? -3.30672  -9.61084  27.28227  1.000 19.74519  ? 47  HIS H H    1 
ATOM   667  H HA   . HIS A 1 47  ? -1.38845  -11.23867 28.12460  1.000 17.71833  ? 47  HIS H HA   1 
ATOM   668  H HB2  . HIS A 1 47  ? -2.69614  -9.87565  29.59977  1.000 16.51594  ? 47  HIS H HB2  1 
ATOM   669  H HB3  . HIS A 1 47  ? -3.92397  -10.84441 29.31807  1.000 16.51594  ? 47  HIS H HB3  1 
ATOM   670  H HD1  . HIS A 1 47  ? -4.22388  -12.61192 30.98285  1.000 16.40452  ? 47  HIS H HD1  1 
ATOM   671  H HD2  . HIS A 1 47  ? -0.53731  -11.36365 30.90167  1.000 14.91721  ? 47  HIS H HD2  1 
ATOM   672  H HE1  . HIS A 1 47  ? -3.10731  -13.76385 32.71923  1.000 19.41489  ? 47  HIS H HE1  1 
ATOM   673  N N    . ILE A 1 48  ? -2.03250  -13.52791 27.60541  1.000 14.38180  ? 48  ILE H N    1 
ATOM   674  C CA   . ILE A 1 48  ? -2.43045  -14.88292 27.24538  1.000 15.34496  ? 48  ILE H CA   1 
ATOM   675  C C    . ILE A 1 48  ? -2.81398  -15.67873 28.47612  1.000 15.84956  ? 48  ILE H C    1 
ATOM   676  O O    . ILE A 1 48  ? -3.82093  -16.39295 28.48971  1.000 10.93748  ? 48  ILE H O    1 
ATOM   677  C CB   . ILE A 1 48  ? -1.29081  -15.60153 26.49007  1.000 11.85010  ? 48  ILE H CB   1 
ATOM   678  C CG1  . ILE A 1 48  ? -0.90110  -14.84132 25.22852  1.000 14.55445  ? 48  ILE H CG1  1 
ATOM   679  C CG2  . ILE A 1 48  ? -1.70767  -17.04141 26.17298  1.000 13.69459  ? 48  ILE H CG2  1 
ATOM   680  C CD1  . ILE A 1 48  ? 0.38112   -15.34207 24.60542  1.000 15.89820  ? 48  ILE H CD1  1 
ATOM   681  H H    . ILE A 1 48  ? -1.20338  -13.45535 27.82198  1.000 17.26500  ? 48  ILE H H    1 
ATOM   682  H HA   . ILE A 1 48  ? -3.19690  -14.81823 26.65439  1.000 18.42078  ? 48  ILE H HA   1 
ATOM   683  H HB   . ILE A 1 48  ? -0.50656  -15.62465 27.06043  1.000 14.22696  ? 48  ILE H HB   1 
ATOM   684  H HG12 . ILE A 1 48  ? -1.60920  -14.93714 24.57254  1.000 17.47217  ? 48  ILE H HG12 1 
ATOM   685  H HG13 . ILE A 1 48  ? -0.77931  -13.90503 25.45086  1.000 17.47217  ? 48  ILE H HG13 1 
ATOM   686  H HG21 . ILE A 1 48  ? -1.09620  -17.40987 25.51629  1.000 16.44034  ? 48  ILE H HG21 1 
ATOM   687  H HG22 . ILE A 1 48  ? -1.67388  -17.56666 26.98776  1.000 16.44034  ? 48  ILE H HG22 1 
ATOM   688  H HG23 . ILE A 1 48  ? -2.61071  -17.03802 25.81883  1.000 16.44034  ? 48  ILE H HG23 1 
ATOM   689  H HD11 . ILE A 1 48  ? 0.66317   -14.71800 23.91849  1.000 19.08467  ? 48  ILE H HD11 1 
ATOM   690  H HD12 . ILE A 1 48  ? 1.06211   -15.40699 25.29313  1.000 19.08467  ? 48  ILE H HD12 1 
ATOM   691  H HD13 . ILE A 1 48  ? 0.22205   -16.21520 24.21396  1.000 19.08467  ? 48  ILE H HD13 1 
ATOM   692  N N    . GLY A 1 49  ? -1.98942  -15.60947 29.50987  1.000 15.53223  ? 49  GLY H N    1 
ATOM   693  C CA   . GLY A 1 49  ? -2.34409  -16.35635 30.70939  1.000 10.76896  ? 49  GLY H CA   1 
ATOM   694  C C    . GLY A 1 49  ? -1.31947  -16.17030 31.79959  1.000 13.46293  ? 49  GLY H C    1 
ATOM   695  O O    . GLY A 1 49  ? -0.22084  -15.66451 31.56795  1.000 12.78769  ? 49  GLY H O    1 
ATOM   696  H H    . GLY A 1 49  ? -1.25626  -15.16112 29.54224  1.000 18.64550  ? 49  GLY H H    1 
ATOM   697  H HA2  . GLY A 1 49  ? -3.20429  -16.05259 31.03907  1.000 12.92959  ? 49  GLY H HA2  1 
ATOM   698  H HA3  . GLY A 1 49  ? -2.40247  -17.30137 30.49860  1.000 12.92959  ? 49  GLY H HA3  1 
ATOM   699  N N    . TYR A 1 50  ? -1.69762  -16.62277 32.99673  1.000 12.67237  ? 50  TYR H N    1 
ATOM   700  C CA   . TYR A 1 50  ? -0.91825  -16.40477 34.21304  1.000 14.61050  ? 50  TYR H CA   1 
ATOM   701  C C    . TYR A 1 50  ? -0.84902  -17.70663 34.99286  1.000 14.02462  ? 50  TYR H C    1 
ATOM   702  O O    . TYR A 1 50  ? -1.88491  -18.28914 35.31811  1.000 17.41702  ? 50  TYR H O    1 
ATOM   703  C CB   . TYR A 1 50  ? -1.54971  -15.30303 35.06740  1.000 17.04439  ? 50  TYR H CB   1 
ATOM   704  C CG   . TYR A 1 50  ? -0.82239  -14.94188 36.34965  1.000 15.47654  ? 50  TYR H CG   1 
ATOM   705  C CD1  . TYR A 1 50  ? 0.49016   -14.49912 36.32646  1.000 14.18163  ? 50  TYR H CD1  1 
ATOM   706  C CD2  . TYR A 1 50  ? -1.47190  -14.99303 37.57979  1.000 16.19926  ? 50  TYR H CD2  1 
ATOM   707  C CE1  . TYR A 1 50  ? 1.14590   -14.13635 37.49251  1.000 12.95351  ? 50  TYR H CE1  1 
ATOM   708  C CE2  . TYR A 1 50  ? -0.82131  -14.63358 38.75250  1.000 14.83767  ? 50  TYR H CE2  1 
ATOM   709  C CZ   . TYR A 1 50  ? 0.48998   -14.20855 38.70144  1.000 12.32227  ? 50  TYR H CZ   1 
ATOM   710  O OH   . TYR A 1 50  ? 1.15781   -13.84615 39.85719  1.000 17.58959  ? 50  TYR H OH   1 
ATOM   711  H H    . TYR A 1 50  ? -2.41992  -17.06964 33.13163  1.000 15.21367  ? 50  TYR H H    1 
ATOM   712  H HA   . TYR A 1 50  ? -0.01387  -16.14368 33.97887  1.000 17.53943  ? 50  TYR H HA   1 
ATOM   713  H HB2  . TYR A 1 50  ? -1.59847  -14.49630 34.53101  1.000 20.46010  ? 50  TYR H HB2  1 
ATOM   714  H HB3  . TYR A 1 50  ? -2.44203  -15.58963 35.31743  1.000 20.46010  ? 50  TYR H HB3  1 
ATOM   715  H HD1  . TYR A 1 50  ? 0.93933   -14.44431 35.51396  1.000 17.02479  ? 50  TYR H HD1  1 
ATOM   716  H HD2  . TYR A 1 50  ? -2.35794  -15.27313 37.61681  1.000 19.44594  ? 50  TYR H HD2  1 
ATOM   717  H HE1  . TYR A 1 50  ? 2.02822   -13.84438 37.45859  1.000 15.55105  ? 50  TYR H HE1  1 
ATOM   718  H HE2  . TYR A 1 50  ? -1.26693  -14.67909 39.56752  1.000 17.81204  ? 50  TYR H HE2  1 
ATOM   719  H HH   . TYR A 1 50  ? 1.94175   -13.60709 39.67307  1.000 21.11434  ? 50  TYR H HH   1 
ATOM   720  N N    . LEU A 1 51  ? 0.36526   -18.16428 35.26738  1.000 14.30524  ? 51  LEU H N    1 
ATOM   721  C CA   . LEU A 1 51  ? 0.62233   -19.34169 36.08645  1.000 17.11764  ? 51  LEU H CA   1 
ATOM   722  C C    . LEU A 1 51  ? 1.08469   -18.85470 37.45375  1.000 13.14902  ? 51  LEU H C    1 
ATOM   723  O O    . LEU A 1 51  ? 2.19036   -18.31957 37.58141  1.000 13.60950  ? 51  LEU H O    1 
ATOM   724  C CB   . LEU A 1 51  ? 1.67978   -20.22739 35.43051  1.000 12.90609  ? 51  LEU H CB   1 
ATOM   725  C CG   . LEU A 1 51  ? 2.09863   -21.48522 36.18995  1.000 15.58444  ? 51  LEU H CG   1 
ATOM   726  C CD1  . LEU A 1 51  ? 0.92718   -22.44480 36.29955  1.000 16.44049  ? 51  LEU H CD1  1 
ATOM   727  C CD2  . LEU A 1 51  ? 3.28915   -22.17070 35.50850  1.000 15.52378  ? 51  LEU H CD2  1 
ATOM   728  H H    . LEU A 1 51  ? 1.08616   -17.79469 34.97874  1.000 17.17313  ? 51  LEU H H    1 
ATOM   729  H HA   . LEU A 1 51  ? -0.18855  -19.86336 36.19248  1.000 20.54800  ? 51  LEU H HA   1 
ATOM   730  H HB2  . LEU A 1 51  ? 1.33526   -20.51719 34.57131  1.000 15.49414  ? 51  LEU H HB2  1 
ATOM   731  H HB3  . LEU A 1 51  ? 2.47976   -19.69356 35.30423  1.000 15.49414  ? 51  LEU H HB3  1 
ATOM   732  H HG   . LEU A 1 51  ? 2.37696   -21.23224 37.08405  1.000 18.70817  ? 51  LEU H HG   1 
ATOM   733  H HD11 . LEU A 1 51  ? 1.22413   -23.25673 36.73943  1.000 19.73543  ? 51  LEU H HD11 1 
ATOM   734  H HD12 . LEU A 1 51  ? 0.22320   -22.02573 36.81888  1.000 19.73543  ? 51  LEU H HD12 1 
ATOM   735  H HD13 . LEU A 1 51  ? 0.60322   -22.65072 35.40874  1.000 19.73543  ? 51  LEU H HD13 1 
ATOM   736  H HD21 . LEU A 1 51  ? 3.52192   -22.96915 36.00770  1.000 18.63537  ? 51  LEU H HD21 1 
ATOM   737  H HD22 . LEU A 1 51  ? 3.03999   -22.40844 34.60169  1.000 18.63537  ? 51  LEU H HD22 1 
ATOM   738  H HD23 . LEU A 1 51  ? 4.04104   -21.55802 35.49512  1.000 18.63537  ? 51  LEU H HD23 1 
ATOM   739  N N    . THR A 1 52  ? 0.23213   -19.02052 38.46431  1.000 14.11334  ? 52  THR H N    1 
ATOM   740  C CA   . THR A 1 52  ? 0.53839   -18.52817 39.79718  1.000 14.07048  ? 52  THR H CA   1 
ATOM   741  C C    . THR A 1 52  ? 1.70689   -19.29327 40.40642  1.000 17.70478  ? 52  THR H C    1 
ATOM   742  O O    . THR A 1 52  ? 2.03409   -20.41269 40.00301  1.000 20.62395  ? 52  THR H O    1 
ATOM   743  C CB   . THR A 1 52  ? -0.67087  -18.66216 40.72435  1.000 18.19823  ? 52  THR H CB   1 
ATOM   744  O OG1  . THR A 1 52  ? -0.93056  -20.05265 40.96265  1.000 17.45339  ? 52  THR H OG1  1 
ATOM   745  C CG2  . THR A 1 52  ? -1.90325  -18.00577 40.11160  1.000 16.68051  ? 52  THR H CG2  1 
ATOM   746  H H    . THR A 1 52  ? -0.52929  -19.41520 38.40049  1.000 16.94285  ? 52  THR H H    1 
ATOM   747  H HA   . THR A 1 52  ? 0.77600   -17.59032 39.72736  1.000 16.89141  ? 52  THR H HA   1 
ATOM   748  H HB   . THR A 1 52  ? -0.48678  -18.21621 41.56587  1.000 21.84471  ? 52  THR H HB   1 
ATOM   749  H HG1  . THR A 1 52  ? -1.60174  -20.13838 41.46042  1.000 20.95090  ? 52  THR H HG1  1 
ATOM   750  H HG21 . THR A 1 52  ? -2.62962  -17.99874 40.75443  1.000 20.02345  ? 52  THR H HG21 1 
ATOM   751  H HG22 . THR A 1 52  ? -1.70017  -17.09233 39.85607  1.000 20.02345  ? 52  THR H HG22 1 
ATOM   752  H HG23 . THR A 1 52  ? -2.18435  -18.49779 39.32433  1.000 20.02345  ? 52  THR H HG23 1 
ATOM   753  N N    . ALA A 1 53  ? 2.33000   -18.66926 41.41068  1.000 21.40872  ? 53  ALA H N    1 
ATOM   754  C CA   . ALA A 1 53  ? 3.33059   -19.36340 42.21363  1.000 22.99619  ? 53  ALA H CA   1 
ATOM   755  C C    . ALA A 1 53  ? 2.78085   -20.66082 42.79352  1.000 24.25439  ? 53  ALA H C    1 
ATOM   756  O O    . ALA A 1 53  ? 3.53553   -21.61468 43.00469  1.000 24.64743  ? 53  ALA H O    1 
ATOM   757  C CB   . ALA A 1 53  ? 3.82553   -18.44946 43.33734  1.000 21.92434  ? 53  ALA H CB   1 
ATOM   758  H H    . ALA A 1 53  ? 2.19119   -17.85295 41.64300  1.000 25.69729  ? 53  ALA H H    1 
ATOM   759  H HA   . ALA A 1 53  ? 4.08866   -19.58327 41.64982  1.000 27.60226  ? 53  ALA H HA   1 
ATOM   760  H HB1  . ALA A 1 53  ? 4.49029   -18.92397 43.86064  1.000 26.31604  ? 53  ALA H HB1  1 
ATOM   761  H HB2  . ALA A 1 53  ? 4.21860   -17.65328 42.94684  1.000 26.31604  ? 53  ALA H HB2  1 
ATOM   762  H HB3  . ALA A 1 53  ? 3.07406   -18.20547 43.90006  1.000 26.31604  ? 53  ALA H HB3  1 
ATOM   763  N N    . GLY A 1 54  ? 1.47205   -20.71929 43.04749  1.000 23.60676  ? 54  GLY H N    1 
ATOM   764  C CA   . GLY A 1 54  ? 0.83818   -21.92356 43.54705  1.000 23.93477  ? 54  GLY H CA   1 
ATOM   765  C C    . GLY A 1 54  ? 0.59415   -23.00682 42.51635  1.000 27.22294  ? 54  GLY H C    1 
ATOM   766  O O    . GLY A 1 54  ? 0.13301   -24.09293 42.88090  1.000 25.88239  ? 54  GLY H O    1 
ATOM   767  H H    . GLY A 1 54  ? 0.92806   -20.06277 42.93503  1.000 28.33494  ? 54  GLY H H    1 
ATOM   768  H HA2  . GLY A 1 54  ? 1.39920   -22.30137 44.24233  1.000 28.72856  ? 54  GLY H HA2  1 
ATOM   769  H HA3  . GLY A 1 54  ? -0.02043  -21.68392 43.92950  1.000 28.72856  ? 54  GLY H HA3  1 
ATOM   770  N N    . GLY A 1 55  ? 0.86840   -22.73888 41.24254  1.000 25.32477  ? 55  GLY H N    1 
ATOM   771  C CA   . GLY A 1 55  ? 0.75630   -23.75237 40.21394  1.000 27.06772  ? 55  GLY H CA   1 
ATOM   772  C C    . GLY A 1 55  ? -0.58125  -23.83168 39.51664  1.000 20.16399  ? 55  GLY H C    1 
ATOM   773  O O    . GLY A 1 55  ? -0.86219  -24.84211 38.86433  1.000 24.52843  ? 55  GLY H O    1 
ATOM   774  H H    . GLY A 1 55  ? 1.12281   -21.97056 40.95176  1.000 30.39656  ? 55  GLY H H    1 
ATOM   775  H HA2  . GLY A 1 55  ? 1.42907   -23.57898 39.53703  1.000 32.48810  ? 55  GLY H HA2  1 
ATOM   776  H HA3  . GLY A 1 55  ? 0.92837   -24.61834 40.61568  1.000 32.48810  ? 55  GLY H HA3  1 
ATOM   777  N N    . ARG A 1 56  ? -1.41843  -22.80781 39.62914  1.000 15.98809  ? 56  ARG H N    1 
ATOM   778  C CA   . ARG A 1 56  ? -2.68523  -22.76066 38.92034  1.000 18.39839  ? 56  ARG H CA   1 
ATOM   779  C C    . ARG A 1 56  ? -2.55807  -21.82675 37.72355  1.000 16.18072  ? 56  ARG H C    1 
ATOM   780  O O    . ARG A 1 56  ? -2.06059  -20.70377 37.85897  1.000 17.21926  ? 56  ARG H O    1 
ATOM   781  C CB   . ARG A 1 56  ? -3.81310  -22.29610 39.83999  1.000 19.41115  ? 56  ARG H CB   1 
ATOM   782  C CG   . ARG A 1 56  ? -5.02784  -23.21331 39.77957  1.000 28.70488  ? 56  ARG H CG   1 
ATOM   783  C CD   . ARG A 1 56  ? -6.27547  -22.58289 40.37064  1.000 30.83991  ? 56  ARG H CD   1 
ATOM   784  N NE   . ARG A 1 56  ? -6.02607  -21.87453 41.61930  1.000 21.13263  ? 56  ARG H NE   1 
ATOM   785  C CZ   . ARG A 1 56  ? -6.98617  -21.43358 42.41962  1.000 23.10318  ? 56  ARG H CZ   1 
ATOM   786  N NH1  . ARG A 1 56  ? -8.26108  -21.64725 42.14603  1.000 19.87175  ? 56  ARG H NH1  1 
ATOM   787  N NH2  . ARG A 1 56  ? -6.65940  -20.76485 43.52248  1.000 24.04261  ? 56  ARG H NH2  1 
ATOM   788  H H    . ARG A 1 56  ? -1.26981  -22.11723 40.11966  1.000 19.19254  ? 56  ARG H H    1 
ATOM   789  H HA   . ARG A 1 56  ? -2.90923  -23.64750 38.59748  1.000 22.08490  ? 56  ARG H HA   1 
ATOM   790  H HB2  . ARG A 1 56  ? -3.49070  -22.28224 40.75473  1.000 23.30021  ? 56  ARG H HB2  1 
ATOM   791  H HB3  . ARG A 1 56  ? -4.09320  -21.40650 39.57343  1.000 23.30021  ? 56  ARG H HB3  1 
ATOM   792  H HG2  . ARG A 1 56  ? -5.21349  -23.43078 38.85268  1.000 34.45269  ? 56  ARG H HG2  1 
ATOM   793  H HG3  . ARG A 1 56  ? -4.83724  -24.02300 40.27855  1.000 34.45269  ? 56  ARG H HG3  1 
ATOM   794  H HD2  . ARG A 1 56  ? -6.63753  -21.94631 39.73456  1.000 37.01472  ? 56  ARG H HD2  1 
ATOM   795  H HD3  . ARG A 1 56  ? -6.92577  -23.28020 40.54885  1.000 37.01472  ? 56  ARG H HD3  1 
ATOM   796  H HE   . ARG A 1 56  ? -5.20952  -21.73461 41.85010  1.000 25.36598  ? 56  ARG H HE   1 
ATOM   797  H HH11 . ARG A 1 56  ? -8.48191  -22.08023 41.43655  1.000 23.85294  ? 56  ARG H HH11 1 
ATOM   798  H HH12 . ARG A 1 56  ? -8.87003  -21.35334 42.67743  1.000 23.85294  ? 56  ARG H HH12 1 
ATOM   799  H HH21 . ARG A 1 56  ? -5.83221  -20.62263 43.70991  1.000 28.85797  ? 56  ARG H HH21 1 
ATOM   800  H HH22 . ARG A 1 56  ? -7.27537  -20.47483 44.04790  1.000 28.85797  ? 56  ARG H HH22 1 
ATOM   801  N N    . ALA A 1 57  ? -3.01415  -22.29005 36.56493  1.000 15.37757  ? 57  ALA H N    1 
ATOM   802  C CA   . ALA A 1 57  ? -2.93024  -21.52883 35.32709  1.000 17.76144  ? 57  ALA H CA   1 
ATOM   803  C C    . ALA A 1 57  ? -4.29728  -20.94552 34.99066  1.000 20.31329  ? 57  ALA H C    1 
ATOM   804  O O    . ALA A 1 57  ? -5.27176  -21.68150 34.80373  1.000 19.16870  ? 57  ALA H O    1 
ATOM   805  C CB   . ALA A 1 57  ? -2.41983  -22.40323 34.18133  1.000 21.83251  ? 57  ALA H CB   1 
ATOM   806  H H    . ALA A 1 57  ? -3.38451  -23.06038 36.46998  1.000 18.45992  ? 57  ALA H H    1 
ATOM   807  H HA   . ALA A 1 57  ? -2.31146  -20.79207 35.45039  1.000 21.32056  ? 57  ALA H HA   1 
ATOM   808  H HB1  . ALA A 1 57  ? -2.36863  -21.86782 33.37410  1.000 26.20585  ? 57  ALA H HB1  1 
ATOM   809  H HB2  . ALA A 1 57  ? -1.54006  -22.74170 34.41011  1.000 26.20585  ? 57  ALA H HB2  1 
ATOM   810  H HB3  . ALA A 1 57  ? -3.03455  -23.14197 34.04983  1.000 26.20585  ? 57  ALA H HB3  1 
ATOM   811  N N    . PHE A 1 58  ? -4.35626  -19.63051 34.90655  1.000 15.38695  ? 58  PHE H N    1 
ATOM   812  C CA   . PHE A 1 58  ? -5.55253  -18.89178 34.54115  1.000 17.24215  ? 58  PHE H CA   1 
ATOM   813  C C    . PHE A 1 58  ? -5.33860  -18.35588 33.13404  1.000 17.50561  ? 58  PHE H C    1 
ATOM   814  O O    . PHE A 1 58  ? -4.47500  -17.50118 32.92087  1.000 17.39342  ? 58  PHE H O    1 
ATOM   815  C CB   . PHE A 1 58  ? -5.80070  -17.75469 35.52333  1.000 17.24056  ? 58  PHE H CB   1 
ATOM   816  C CG   . PHE A 1 58  ? -6.02354  -18.21008 36.93429  1.000 15.60938  ? 58  PHE H CG   1 
ATOM   817  C CD1  . PHE A 1 58  ? -7.28465  -18.59113 37.35507  1.000 16.43726  ? 58  PHE H CD1  1 
ATOM   818  C CD2  . PHE A 1 58  ? -4.97634  -18.25518 37.83943  1.000 15.05628  ? 58  PHE H CD2  1 
ATOM   819  C CE1  . PHE A 1 58  ? -7.50092  -19.00258 38.65536  1.000 16.55293  ? 58  PHE H CE1  1 
ATOM   820  C CE2  . PHE A 1 58  ? -5.18594  -18.66932 39.13846  1.000 17.82796  ? 58  PHE H CE2  1 
ATOM   821  C CZ   . PHE A 1 58  ? -6.44811  -19.04408 39.54610  1.000 19.47065  ? 58  PHE H CZ   1 
ATOM   822  H H    . PHE A 1 58  ? -3.68413  -19.11760 35.06388  1.000 18.47117  ? 58  PHE H H    1 
ATOM   823  H HA   . PHE A 1 58  ? -6.32544  -19.47784 34.54793  1.000 20.69742  ? 58  PHE H HA   1 
ATOM   824  H HB2  . PHE A 1 58  ? -5.02910  -17.16687 35.52076  1.000 20.69550  ? 58  PHE H HB2  1 
ATOM   825  H HB3  . PHE A 1 58  ? -6.59041  -17.26677 35.24192  1.000 20.69550  ? 58  PHE H HB3  1 
ATOM   826  H HD1  . PHE A 1 58  ? -7.99520  -18.57001 36.75542  1.000 19.73155  ? 58  PHE H HD1  1 
ATOM   827  H HD2  . PHE A 1 58  ? -4.12292  -18.00365 37.56867  1.000 18.07437  ? 58  PHE H HD2  1 
ATOM   828  H HE1  . PHE A 1 58  ? -8.35400  -19.25106 38.92995  1.000 19.87034  ? 58  PHE H HE1  1 
ATOM   829  H HE2  . PHE A 1 58  ? -4.47611  -18.69564 39.73875  1.000 21.40039  ? 58  PHE H HE2  1 
ATOM   830  H HZ   . PHE A 1 58  ? -6.59005  -19.32482 40.42128  1.000 23.37161  ? 58  PHE H HZ   1 
ATOM   831  N N    . TYR A 1 59  ? -6.12896  -18.83847 32.18244  1.000 15.42187  ? 59  TYR H N    1 
ATOM   832  C CA   . TYR A 1 59  ? -5.99130  -18.43319 30.78962  1.000 16.24563  ? 59  TYR H CA   1 
ATOM   833  C C    . TYR A 1 59  ? -7.02569  -17.38576 30.41794  1.000 22.46861  ? 59  TYR H C    1 
ATOM   834  O O    . TYR A 1 59  ? -8.16193  -17.42493 30.89329  1.000 15.63359  ? 59  TYR H O    1 
ATOM   835  C CB   . TYR A 1 59  ? -6.13697  -19.63378 29.86383  1.000 14.82338  ? 59  TYR H CB   1 
ATOM   836  C CG   . TYR A 1 59  ? -5.14837  -20.72124 30.18058  1.000 18.39873  ? 59  TYR H CG   1 
ATOM   837  C CD1  . TYR A 1 59  ? -3.85307  -20.65647 29.70283  1.000 16.54570  ? 59  TYR H CD1  1 
ATOM   838  C CD2  . TYR A 1 59  ? -5.50531  -21.80220 30.97184  1.000 16.76537  ? 59  TYR H CD2  1 
ATOM   839  C CE1  . TYR A 1 59  ? -2.93774  -21.63963 29.99521  1.000 17.14287  ? 59  TYR H CE1  1 
ATOM   840  C CE2  . TYR A 1 59  ? -4.59629  -22.79450 31.26509  1.000 19.03626  ? 59  TYR H CE2  1 
ATOM   841  C CZ   . TYR A 1 59  ? -3.30909  -22.70430 30.77603  1.000 18.05807  ? 59  TYR H CZ   1 
ATOM   842  O OH   . TYR A 1 59  ? -2.38401  -23.67711 31.06918  1.000 18.42832  ? 59  TYR H OH   1 
ATOM   843  H H    . TYR A 1 59  ? -6.75863  -19.40770 32.32062  1.000 18.51308  ? 59  TYR H H    1 
ATOM   844  H HA   . TYR A 1 59  ? -5.11275  -18.04045 30.66793  1.000 19.50159  ? 59  TYR H HA   1 
ATOM   845  H HB2  . TYR A 1 59  ? -7.03009  -20.00046 29.95750  1.000 17.79490  ? 59  TYR H HB2  1 
ATOM   846  H HB3  . TYR A 1 59  ? -5.98974  -19.34860 28.94846  1.000 17.79490  ? 59  TYR H HB3  1 
ATOM   847  H HD1  . TYR A 1 59  ? -3.59630  -19.93545 29.17452  1.000 19.86167  ? 59  TYR H HD1  1 
ATOM   848  H HD2  . TYR A 1 59  ? -6.37018  -21.85805 31.30917  1.000 20.12528  ? 59  TYR H HD2  1 
ATOM   849  H HE1  . TYR A 1 59  ? -2.07023  -21.58304 29.66488  1.000 20.57827  ? 59  TYR H HE1  1 
ATOM   850  H HE2  . TYR A 1 59  ? -4.84827  -23.52032 31.78910  1.000 22.85035  ? 59  TYR H HE2  1 
ATOM   851  H HH   . TYR A 1 59  ? -2.73310  -24.26947 31.55171  1.000 22.12081  ? 59  TYR H HH   1 
ATOM   852  N N    . ALA A 1 60  ? -6.62070  -16.45007 29.56382  1.000 17.07247  ? 60  ALA H N    1 
ATOM   853  C CA   . ALA A 1 60  ? -7.58661  -15.59411 28.89192  1.000 21.44717  ? 60  ALA H CA   1 
ATOM   854  C C    . ALA A 1 60  ? -8.62661  -16.45562 28.19235  1.000 19.57414  ? 60  ALA H C    1 
ATOM   855  O O    . ALA A 1 60  ? -8.32197  -17.54334 27.69638  1.000 17.89697  ? 60  ALA H O    1 
ATOM   856  C CB   . ALA A 1 60  ? -6.89131  -14.69056 27.87556  1.000 17.92351  ? 60  ALA H CB   1 
ATOM   857  H H    . ALA A 1 60  ? -5.80021  -16.29345 29.35921  1.000 20.49380  ? 60  ALA H H    1 
ATOM   858  H HA   . ALA A 1 60  ? -8.02702  -15.02375 29.54125  1.000 25.74343  ? 60  ALA H HA   1 
ATOM   859  H HB1  . ALA A 1 60  ? -7.55550  -14.12971 27.44521  1.000 21.51505  ? 60  ALA H HB1  1 
ATOM   860  H HB2  . ALA A 1 60  ? -6.24084  -14.13834 28.33690  1.000 21.51505  ? 60  ALA H HB2  1 
ATOM   861  H HB3  . ALA A 1 60  ? -6.44632  -15.24318 27.21412  1.000 21.51505  ? 60  ALA H HB3  1 
ATOM   862  N N    . SER A 1 61  ? -9.87093  -15.96802 28.16270  1.000 22.53731  ? 61  SER H N    1 
ATOM   863  C CA   . SER A 1 61  ? -10.95976 -16.77010 27.61268  1.000 23.37140  ? 61  SER H CA   1 
ATOM   864  C C    . SER A 1 61  ? -10.68686 -17.15416 26.16380  1.000 21.16119  ? 61  SER H C    1 
ATOM   865  O O    . SER A 1 61  ? -10.99176 -18.27541 25.74063  1.000 19.86697  ? 61  SER H O    1 
ATOM   866  C CB   . SER A 1 61  ? -12.28416 -16.00759 27.72839  1.000 31.40354  ? 61  SER H CB   1 
ATOM   867  O OG   . SER A 1 61  ? -12.24178 -14.79654 26.99495  1.000 40.17281  ? 61  SER H OG   1 
ATOM   868  H H    . SER A 1 61  ? -10.10424 -15.19148 28.44934  1.000 27.05160  ? 61  SER H H    1 
ATOM   869  H HA   . SER A 1 61  ? -11.03731 -17.58748 28.12919  1.000 28.05251  ? 61  SER H HA   1 
ATOM   870  H HB2  . SER A 1 61  ? -12.99842 -16.56266 27.37821  1.000 37.69108  ? 61  SER H HB2  1 
ATOM   871  H HB3  . SER A 1 61  ? -12.44955 -15.80419 28.66230  1.000 37.69108  ? 61  SER H HB3  1 
ATOM   872  H HG   . SER A 1 61  ? -12.96931 -14.38491 27.07774  1.000 48.21421  ? 61  SER H HG   1 
ATOM   873  N N    . TRP A 1 62  ? -10.09360 -16.24580 25.38997  1.000 18.49212  ? 62  TRP H N    1 
ATOM   874  C CA   . TRP A 1 62  ? -9.83884  -16.54088 23.98629  1.000 19.62413  ? 62  TRP H CA   1 
ATOM   875  C C    . TRP A 1 62  ? -8.75701  -17.59393 23.80162  1.000 22.12908  ? 62  TRP H C    1 
ATOM   876  O O    . TRP A 1 62  ? -8.69502  -18.21977 22.73570  1.000 18.45700  ? 62  TRP H O    1 
ATOM   877  C CB   . TRP A 1 62  ? -9.44863  -15.26352 23.23759  1.000 22.98171  ? 62  TRP H CB   1 
ATOM   878  C CG   . TRP A 1 62  ? -8.15810  -14.64264 23.69014  1.000 19.60555  ? 62  TRP H CG   1 
ATOM   879  C CD1  . TRP A 1 62  ? -8.01219  -13.62544 24.58184  1.000 22.10860  ? 62  TRP H CD1  1 
ATOM   880  C CD2  . TRP A 1 62  ? -6.83265  -14.99753 23.26393  1.000 16.38354  ? 62  TRP H CD2  1 
ATOM   881  N NE1  . TRP A 1 62  ? -6.67787  -13.32162 24.74135  1.000 24.51713  ? 62  TRP H NE1  1 
ATOM   882  C CE2  . TRP A 1 62  ? -5.93430  -14.15039 23.94273  1.000 24.44047  ? 62  TRP H CE2  1 
ATOM   883  C CE3  . TRP A 1 62  ? -6.31966  -15.95013 22.37691  1.000 23.70782  ? 62  TRP H CE3  1 
ATOM   884  C CZ2  . TRP A 1 62  ? -4.55013  -14.23080 23.76631  1.000 18.88618  ? 62  TRP H CZ2  1 
ATOM   885  C CZ3  . TRP A 1 62  ? -4.94689  -16.02703 22.20194  1.000 21.62838  ? 62  TRP H CZ3  1 
ATOM   886  C CH2  . TRP A 1 62  ? -4.07897  -15.16956 22.89230  1.000 21.16995  ? 62  TRP H CH2  1 
ATOM   887  H H    . TRP A 1 62  ? -9.83499  -15.46788 25.64990  1.000 22.19738  ? 62  TRP H H    1 
ATOM   888  H HA   . TRP A 1 62  ? -10.65757 -16.88066 23.59243  1.000 23.55579  ? 62  TRP H HA   1 
ATOM   889  H HB2  . TRP A 1 62  ? -9.35710  -15.47395 22.29513  1.000 27.58489  ? 62  TRP H HB2  1 
ATOM   890  H HB3  . TRP A 1 62  ? -10.14982 -14.60530 23.36398  1.000 27.58489  ? 62  TRP H HB3  1 
ATOM   891  H HD1  . TRP A 1 62  ? -8.71178  -13.19727 25.02018  1.000 26.53716  ? 62  TRP H HD1  1 
ATOM   892  H HE1  . TRP A 1 62  ? -6.36275  -12.71085 25.25832  1.000 29.42739  ? 62  TRP H HE1  1 
ATOM   893  H HE3  . TRP A 1 62  ? -6.88905  -16.52100 21.91343  1.000 28.45622  ? 62  TRP H HE3  1 
ATOM   894  H HZ2  . TRP A 1 62  ? -3.97152  -13.66658 24.22649  1.000 22.67025  ? 62  TRP H HZ2  1 
ATOM   895  H HZ3  . TRP A 1 62  ? -4.59550  -16.65838 21.61643  1.000 25.96089  ? 62  TRP H HZ3  1 
ATOM   896  H HH2  . TRP A 1 62  ? -3.16235  -15.24120 22.75236  1.000 25.41078  ? 62  TRP H HH2  1 
ATOM   897  N N    . ALA A 1 63  ? -7.92115  -17.81646 24.81793  1.000 21.19832  ? 63  ALA H N    1 
ATOM   898  C CA   . ALA A 1 63  ? -6.74776  -18.66976 24.70023  1.000 18.82465  ? 63  ALA H CA   1 
ATOM   899  C C    . ALA A 1 63  ? -6.90983  -20.02565 25.37199  1.000 16.62092  ? 63  ALA H C    1 
ATOM   900  O O    . ALA A 1 63  ? -6.11038  -20.92998 25.10199  1.000 16.82333  ? 63  ALA H O    1 
ATOM   901  C CB   . ALA A 1 63  ? -5.52421  -17.95643 25.30403  1.000 19.58453  ? 63  ALA H CB   1 
ATOM   902  H H    . ALA A 1 63  ? -8.01825  -17.47492 25.60121  1.000 25.44481  ? 63  ALA H H    1 
ATOM   903  H HA   . ALA A 1 63  ? -6.57468  -18.83036 23.75941  1.000 22.59641  ? 63  ALA H HA   1 
ATOM   904  H HB1  . ALA A 1 63  ? -4.74802  -18.53144 25.21574  1.000 23.50827  ? 63  ALA H HB1  1 
ATOM   905  H HB2  . ALA A 1 63  ? -5.37599  -17.12507 24.82678  1.000 23.50827  ? 63  ALA H HB2  1 
ATOM   906  H HB3  . ALA A 1 63  ? -5.69572  -17.77384 26.24113  1.000 23.50827  ? 63  ALA H HB3  1 
ATOM   907  N N    . LYS A 1 64  ? -7.93987  -20.19990 26.20263  1.000 17.38054  ? 64  LYS H N    1 
ATOM   908  C CA   . LYS A 1 64  ? -7.98365  -21.33506 27.11960  1.000 15.76398  ? 64  LYS H CA   1 
ATOM   909  C C    . LYS A 1 64  ? -8.09153  -22.66075 26.38104  1.000 15.52579  ? 64  LYS H C    1 
ATOM   910  O O    . LYS A 1 64  ? -7.48087  -23.65341 26.78952  1.000 20.80636  ? 64  LYS H O    1 
ATOM   911  C CB   . LYS A 1 64  ? -9.15573  -21.17348 28.08836  1.000 16.60267  ? 64  LYS H CB   1 
ATOM   912  C CG   . LYS A 1 64  ? -9.29676  -22.31200 29.08311  1.000 21.47065  ? 64  LYS H CG   1 
ATOM   913  C CD   . LYS A 1 64  ? -10.08103 -21.89451 30.32360  1.000 27.43166  ? 64  LYS H CD   1 
ATOM   914  C CE   . LYS A 1 64  ? -11.54272 -21.59189 30.00363  1.000 35.40393  ? 64  LYS H CE   1 
ATOM   915  N NZ   . LYS A 1 64  ? -12.28691 -22.80660 29.54915  1.000 42.67088  ? 64  LYS H NZ   1 
ATOM   916  H H    . LYS A 1 64  ? -8.62135  -19.67783 26.25393  1.000 20.86349  ? 64  LYS H H    1 
ATOM   917  H HA   . LYS A 1 64  ? -7.15793  -21.34767 27.62846  1.000 18.92361  ? 64  LYS H HA   1 
ATOM   918  H HB2  . LYS A 1 64  ? -9.03121  -20.35450 28.59300  1.000 19.93004  ? 64  LYS H HB2  1 
ATOM   919  H HB3  . LYS A 1 64  ? -9.97804  -21.12573 27.57608  1.000 19.93004  ? 64  LYS H HB3  1 
ATOM   920  H HG2  . LYS A 1 64  ? -9.76705  -23.04807 28.66132  1.000 25.77162  ? 64  LYS H HG2  1 
ATOM   921  H HG3  . LYS A 1 64  ? -8.41470  -22.60024 29.36559  1.000 25.77162  ? 64  LYS H HG3  1 
ATOM   922  H HD2  . LYS A 1 64  ? -10.05649 -22.61398 30.97372  1.000 32.92482  ? 64  LYS H HD2  1 
ATOM   923  H HD3  . LYS A 1 64  ? -9.68176  -21.09424 30.69917  1.000 32.92482  ? 64  LYS H HD3  1 
ATOM   924  H HE2  . LYS A 1 64  ? -11.97886 -21.25135 30.80032  1.000 42.49155  ? 64  LYS H HE2  1 
ATOM   925  H HE3  . LYS A 1 64  ? -11.58296 -20.93070 29.29504  1.000 42.49155  ? 64  LYS H HE3  1 
ATOM   926  H HZ1  . LYS A 1 64  ? -13.13942 -22.60181 29.39626  1.000 51.21189  ? 64  LYS H HZ1  1 
ATOM   927  H HZ2  . LYS A 1 64  ? -11.92642 -23.12141 28.79878  1.000 51.21189  ? 64  LYS H HZ2  1 
ATOM   928  H HZ3  . LYS A 1 64  ? -12.24936 -23.43842 30.17484  1.000 51.21189  ? 64  LYS H HZ3  1 
ATOM   929  N N    . SER A 1 65  ? -8.86938  -22.70610 25.30260  1.000 18.96909  ? 65  SER H N    1 
ATOM   930  C CA   . SER A 1 65  ? -9.11697  -23.98215 24.64576  1.000 19.77140  ? 65  SER H CA   1 
ATOM   931  C C    . SER A 1 65  ? -7.89323  -24.50100 23.90721  1.000 19.80529  ? 65  SER H C    1 
ATOM   932  O O    . SER A 1 65  ? -7.83669  -25.69663 23.60002  1.000 20.83331  ? 65  SER H O    1 
ATOM   933  C CB   . SER A 1 65  ? -10.28913 -23.85595 23.67330  1.000 20.72144  ? 65  SER H CB   1 
ATOM   934  O OG   . SER A 1 65  ? -9.93625  -23.06452 22.55480  1.000 27.51828  ? 65  SER H OG   1 
ATOM   935  H H    . SER A 1 65  ? -9.25576  -22.02818 24.94101  1.000 22.76974  ? 65  SER H H    1 
ATOM   936  H HA   . SER A 1 65  ? -9.35657  -24.63393 25.32302  1.000 23.73251  ? 65  SER H HA   1 
ATOM   937  H HB2  . SER A 1 65  ? -10.54081 -24.74103 23.36640  1.000 24.87256  ? 65  SER H HB2  1 
ATOM   938  H HB3  . SER A 1 65  ? -11.03548 -23.43905 24.13161  1.000 24.87256  ? 65  SER H HB3  1 
ATOM   939  H HG   . SER A 1 65  ? -10.58698 -23.00705 22.02673  1.000 33.02877  ? 65  SER H HG   1 
ATOM   940  N N    . ARG A 1 66  ? -6.91146  -23.64167 23.62938  1.000 19.46679  ? 66  ARG H N    1 
ATOM   941  C CA   . ARG A 1 66  ? -5.76971  -24.01524 22.81053  1.000 21.82151  ? 66  ARG H CA   1 
ATOM   942  C C    . ARG A 1 66  ? -4.43238  -23.93710 23.52676  1.000 17.09262  ? 66  ARG H C    1 
ATOM   943  O O    . ARG A 1 66  ? -3.43390  -24.40108 22.96939  1.000 19.60118  ? 66  ARG H O    1 
ATOM   944  C CB   . ARG A 1 66  ? -5.68846  -23.12150 21.56087  1.000 20.71307  ? 66  ARG H CB   1 
ATOM   945  C CG   . ARG A 1 66  ? -6.86674  -23.24614 20.62884  1.000 24.14362  ? 66  ARG H CG   1 
ATOM   946  C CD   . ARG A 1 66  ? -6.65955  -22.39561 19.39026  1.000 21.13078  ? 66  ARG H CD   1 
ATOM   947  N NE   . ARG A 1 66  ? -6.60523  -20.97116 19.69599  1.000 19.99176  ? 66  ARG H NE   1 
ATOM   948  C CZ   . ARG A 1 66  ? -5.93510  -20.07712 18.97847  1.000 26.90990  ? 66  ARG H CZ   1 
ATOM   949  N NH1  . ARG A 1 66  ? -5.20287  -20.43448 17.93660  1.000 24.40944  ? 66  ARG H NH1  1 
ATOM   950  N NH2  . ARG A 1 66  ? -5.99350  -18.79386 19.32027  1.000 26.75923  ? 66  ARG H NH2  1 
ATOM   951  H H    . ARG A 1 66  ? -6.88825  -22.82873 23.90902  1.000 23.36698  ? 66  ARG H H    1 
ATOM   952  H HA   . ARG A 1 66  ? -5.90142  -24.93335 22.52657  1.000 26.19264  ? 66  ARG H HA   1 
ATOM   953  H HB2  . ARG A 1 66  ? -5.63612  -22.19569 21.84554  1.000 24.86252  ? 66  ARG H HB2  1 
ATOM   954  H HB3  . ARG A 1 66  ? -4.89229  -23.36038 21.06093  1.000 24.86252  ? 66  ARG H HB3  1 
ATOM   955  H HG2  . ARG A 1 66  ? -6.96757  -24.17113 20.35475  1.000 28.97918  ? 66  ARG H HG2  1 
ATOM   956  H HG3  . ARG A 1 66  ? -7.67077  -22.94417 21.07967  1.000 28.97918  ? 66  ARG H HG3  1 
ATOM   957  H HD2  . ARG A 1 66  ? -5.82179  -22.64551 18.97001  1.000 25.36377  ? 66  ARG H HD2  1 
ATOM   958  H HD3  . ARG A 1 66  ? -7.39584  -22.54394 18.77645  1.000 25.36377  ? 66  ARG H HD3  1 
ATOM   959  H HE   . ARG A 1 66  ? -7.03537  -20.69162 20.38624  1.000 23.99695  ? 66  ARG H HE   1 
ATOM   960  H HH11 . ARG A 1 66  ? -5.15275  -21.26257 17.70997  1.000 29.29816  ? 66  ARG H HH11 1 
ATOM   961  H HH12 . ARG A 1 66  ? -4.77688  -19.83875 17.48577  1.000 29.29816  ? 66  ARG H HH12 1 
ATOM   962  H HH21 . ARG A 1 66  ? -6.46160  -18.55066 19.99949  1.000 32.11791  ? 66  ARG H HH21 1 
ATOM   963  H HH22 . ARG A 1 66  ? -5.56319  -18.20684 18.86219  1.000 32.11791  ? 66  ARG H HH22 1 
ATOM   964  N N    . SER A 1 67  ? -4.37943  -23.38444 24.73348  1.000 18.78660  ? 67  SER H N    1 
ATOM   965  C CA   . SER A 1 67  ? -3.12846  -23.01688 25.37494  1.000 14.66556  ? 67  SER H CA   1 
ATOM   966  C C    . SER A 1 67  ? -2.88438  -23.83788 26.63239  1.000 16.90199  ? 67  SER H C    1 
ATOM   967  O O    . SER A 1 67  ? -3.82104  -24.24117 27.32699  1.000 15.85716  ? 67  SER H O    1 
ATOM   968  C CB   . SER A 1 67  ? -3.12834  -21.53145 25.75375  1.000 15.84403  ? 67  SER H CB   1 
ATOM   969  O OG   . SER A 1 67  ? -3.33286  -20.70953 24.62180  1.000 21.83129  ? 67  SER H OG   1 
ATOM   970  H H    . SER A 1 67  ? -5.07355  -23.20931 25.21006  1.000 22.55075  ? 67  SER H H    1 
ATOM   971  H HA   . SER A 1 67  ? -2.40349  -23.20041 24.75717  1.000 17.60551  ? 67  SER H HA   1 
ATOM   972  H HB2  . SER A 1 67  ? -3.84178  -21.37048 26.39093  1.000 19.01966  ? 67  SER H HB2  1 
ATOM   973  H HB3  . SER A 1 67  ? -2.27194  -21.30955 26.15154  1.000 19.01966  ? 67  SER H HB3  1 
ATOM   974  H HG   . SER A 1 67  ? -4.06505  -20.90013 24.25687  1.000 26.20438  ? 67  SER H HG   1 
ATOM   975  N N    . THR A 1 68  ? -1.60536  -24.06911 26.92571  1.000 13.98903  ? 68  THR H N    1 
ATOM   976  C CA   . THR A 1 68  ? -1.18716  -24.53010 28.24058  1.000 15.03817  ? 68  THR H CA   1 
ATOM   977  C C    . THR A 1 68  ? 0.07934   -23.78206 28.63130  1.000 17.24270  ? 68  THR H C    1 
ATOM   978  O O    . THR A 1 68  ? 0.95838   -23.55440 27.79558  1.000 15.02308  ? 68  THR H O    1 
ATOM   979  C CB   . THR A 1 68  ? -0.93786  -26.04746 28.28719  1.000 21.95973  ? 68  THR H CB   1 
ATOM   980  O OG1  . THR A 1 68  ? 0.18468   -26.38258 27.46754  1.000 29.35340  ? 68  THR H OG1  1 
ATOM   981  C CG2  . THR A 1 68  ? -2.15063  -26.81011 27.80009  1.000 22.52919  ? 68  THR H CG2  1 
ATOM   982  H H    . THR A 1 68  ? -0.95669  -23.96396 26.37094  1.000 16.79368  ? 68  THR H H    1 
ATOM   983  H HA   . THR A 1 68  ? -1.88580  -24.33778 28.88542  1.000 18.05264  ? 68  THR H HA   1 
ATOM   984  H HB   . THR A 1 68  ? -0.75977  -26.30822 29.20435  1.000 26.35851  ? 68  THR H HB   1 
ATOM   985  H HG1  . THR A 1 68  ? 0.89051   -26.08305 27.81059  1.000 35.23091  ? 68  THR H HG1  1 
ATOM   986  H HG21 . THR A 1 68  ? -2.00512  -27.76386 27.90048  1.000 27.04186  ? 68  THR H HG21 1 
ATOM   987  H HG22 . THR A 1 68  ? -2.93193  -26.55493 28.31521  1.000 27.04186  ? 68  THR H HG22 1 
ATOM   988  H HG23 . THR A 1 68  ? -2.31252  -26.61316 26.86419  1.000 27.04186  ? 68  THR H HG23 1 
ATOM   989  N N    . ILE A 1 69  ? 0.13880   -23.36693 29.89252  1.000 14.68324  ? 69  ILE H N    1 
ATOM   990  C CA   . ILE A 1 69  ? 1.31437   -22.73407 30.48078  1.000 12.14739  ? 69  ILE H CA   1 
ATOM   991  C C    . ILE A 1 69  ? 1.75709   -23.62802 31.63045  1.000 16.81662  ? 69  ILE H C    1 
ATOM   992  O O    . ILE A 1 69  ? 0.96953   -23.90384 32.54631  1.000 18.35045  ? 69  ILE H O    1 
ATOM   993  C CB   . ILE A 1 69  ? 1.01647   -21.30528 30.96402  1.000 14.84958  ? 69  ILE H CB   1 
ATOM   994  C CG1  . ILE A 1 69  ? 0.67957   -20.38957 29.77872  1.000 18.26490  ? 69  ILE H CG1  1 
ATOM   995  C CG2  . ILE A 1 69  ? 2.20189   -20.75267 31.74950  1.000 14.43982  ? 69  ILE H CG2  1 
ATOM   996  C CD1  . ILE A 1 69  ? 0.03279   -19.05024 30.17774  1.000 15.29448  ? 69  ILE H CD1  1 
ATOM   997  H H    . ILE A 1 69  ? -0.51376  -23.44403 30.44734  1.000 17.62672  ? 69  ILE H H    1 
ATOM   998  H HA   . ILE A 1 69  ? 2.02996   -22.67862 29.82829  1.000 14.58371  ? 69  ILE H HA   1 
ATOM   999  H HB   . ILE A 1 69  ? 0.24404   -21.33820 31.54982  1.000 17.82633  ? 69  ILE H HB   1 
ATOM   1000 H HG12 . ILE A 1 69  ? 1.49866   -20.18912 29.29934  1.000 21.92471  ? 69  ILE H HG12 1 
ATOM   1001 H HG13 . ILE A 1 69  ? 0.05878   -20.85347 29.19535  1.000 21.92471  ? 69  ILE H HG13 1 
ATOM   1002 H HG21 . ILE A 1 69  ? 2.07333   -19.80117 31.88747  1.000 17.33462  ? 69  ILE H HG21 1 
ATOM   1003 H HG22 . ILE A 1 69  ? 2.25325   -21.20699 32.60499  1.000 17.33462  ? 69  ILE H HG22 1 
ATOM   1004 H HG23 . ILE A 1 69  ? 3.01519   -20.90667 31.24382  1.000 17.33462  ? 69  ILE H HG23 1 
ATOM   1005 H HD11 . ILE A 1 69  ? -0.22841  -18.57388 29.37415  1.000 18.36021  ? 69  ILE H HD11 1 
ATOM   1006 H HD12 . ILE A 1 69  ? -0.74774  -19.22733 30.72574  1.000 18.36021  ? 69  ILE H HD12 1 
ATOM   1007 H HD13 . ILE A 1 69  ? 0.67661   -18.52552 30.67880  1.000 18.36021  ? 69  ILE H HD13 1 
ATOM   1008 N N    . THR A 1 70  ? 2.99544   -24.10931 31.56653  1.000 15.23148  ? 70  THR H N    1 
ATOM   1009 C CA   . THR A 1 70  ? 3.51585   -25.05152 32.55049  1.000 19.99455  ? 70  THR H CA   1 
ATOM   1010 C C    . THR A 1 70  ? 4.90187   -24.61330 32.99604  1.000 19.29186  ? 70  THR H C    1 
ATOM   1011 O O    . THR A 1 70  ? 5.52520   -23.75284 32.38144  1.000 17.01056  ? 70  THR H O    1 
ATOM   1012 C CB   . THR A 1 70  ? 3.58203   -26.47284 31.97943  1.000 24.82433  ? 70  THR H CB   1 
ATOM   1013 O OG1  . THR A 1 70  ? 4.43231   -26.48457 30.82658  1.000 27.45566  ? 70  THR H OG1  1 
ATOM   1014 C CG2  . THR A 1 70  ? 2.19053   -26.95798 31.57782  1.000 29.95658  ? 70  THR H CG2  1 
ATOM   1015 H H    . THR A 1 70  ? 3.56076   -23.90113 30.95279  1.000 18.28461  ? 70  THR H H    1 
ATOM   1016 H HA   . THR A 1 70  ? 2.93116   -25.05205 33.32447  1.000 24.00030  ? 70  THR H HA   1 
ATOM   1017 H HB   . THR A 1 70  ? 3.93422   -27.07466 32.65373  1.000 29.79603  ? 70  THR H HB   1 
ATOM   1018 H HG1  . THR A 1 70  ? 4.12961   -25.96390 30.24103  1.000 32.95363  ? 70  THR H HG1  1 
ATOM   1019 H HG21 . THR A 1 70  ? 2.25748   -27.80055 31.10191  1.000 35.95473  ? 70  THR H HG21 1 
ATOM   1020 H HG22 . THR A 1 70  ? 1.64273   -27.08548 32.36811  1.000 35.95473  ? 70  THR H HG22 1 
ATOM   1021 H HG23 . THR A 1 70  ? 1.76464   -26.30403 31.00174  1.000 35.95473  ? 70  THR H HG23 1 
ATOM   1022 N N    . ARG A 1 71  ? 5.39598   -25.21587 34.07238  1.000 17.17465  ? 71  ARG H N    1 
ATOM   1023 C CA   . ARG A 1 71  ? 6.74282   -24.92072 34.52912  1.000 19.19894  ? 71  ARG H CA   1 
ATOM   1024 C C    . ARG A 1 71  ? 7.44759   -26.21180 34.90796  1.000 18.90106  ? 71  ARG H C    1 
ATOM   1025 O O    . ARG A 1 71  ? 6.81886   -27.20029 35.29671  1.000 19.00995  ? 71  ARG H O    1 
ATOM   1026 C CB   . ARG A 1 71  ? 6.73985   -23.93650 35.70382  1.000 19.52922  ? 71  ARG H CB   1 
ATOM   1027 C CG   . ARG A 1 71  ? 6.27756   -24.52288 37.00265  1.000 20.18529  ? 71  ARG H CG   1 
ATOM   1028 C CD   . ARG A 1 71  ? 6.03366   -23.42858 38.00721  1.000 21.87079  ? 71  ARG H CD   1 
ATOM   1029 N NE   . ARG A 1 71  ? 5.50626   -23.95546 39.25795  1.000 30.54098  ? 71  ARG H NE   1 
ATOM   1030 C CZ   . ARG A 1 71  ? 4.86086   -23.22559 40.15595  1.000 29.83733  ? 71  ARG H CZ   1 
ATOM   1031 N NH1  . ARG A 1 71  ? 4.64410   -21.93482 39.96706  1.000 29.13021  ? 71  ARG H NH1  1 
ATOM   1032 N NH2  . ARG A 1 71  ? 4.41805   -23.80635 41.26726  1.000 31.92015  ? 71  ARG H NH2  1 
ATOM   1033 H H    . ARG A 1 71  ? 4.97225   -25.79340 34.54831  1.000 20.61641  ? 71  ARG H H    1 
ATOM   1034 H HA   . ARG A 1 71  ? 7.24885   -24.51574 33.80743  1.000 23.04556  ? 71  ARG H HA   1 
ATOM   1035 H HB2  . ARG A 1 71  ? 7.64342   -23.60904 35.83504  1.000 23.44190  ? 71  ARG H HB2  1 
ATOM   1036 H HB3  . ARG A 1 71  ? 6.14784   -23.19910 35.48779  1.000 23.44190  ? 71  ARG H HB3  1 
ATOM   1037 H HG2  . ARG A 1 71  ? 5.44927   -25.00863 36.86519  1.000 24.22919  ? 71  ARG H HG2  1 
ATOM   1038 H HG3  . ARG A 1 71  ? 6.95792   -25.11941 37.35215  1.000 24.22919  ? 71  ARG H HG3  1 
ATOM   1039 H HD2  . ARG A 1 71  ? 6.86992   -22.97499 38.19649  1.000 26.25179  ? 71  ARG H HD2  1 
ATOM   1040 H HD3  . ARG A 1 71  ? 5.38947   -22.79968 37.64608  1.000 26.25179  ? 71  ARG H HD3  1 
ATOM   1041 H HE   . ARG A 1 71  ? 5.62065   -24.79149 39.42399  1.000 36.65602  ? 71  ARG H HE   1 
ATOM   1042 H HH11 . ARG A 1 71  ? 4.92408   -21.55226 39.24952  1.000 34.96309  ? 71  ARG H HH11 1 
ATOM   1043 H HH12 . ARG A 1 71  ? 4.22315   -21.47794 40.56176  1.000 34.96309  ? 71  ARG H HH12 1 
ATOM   1044 H HH21 . ARG A 1 71  ? 4.55182   -24.64602 41.39630  1.000 38.31101  ? 71  ARG H HH21 1 
ATOM   1045 H HH22 . ARG A 1 71  ? 3.99789   -23.34225 41.85691  1.000 38.31101  ? 71  ARG H HH22 1 
ATOM   1046 N N    . ASN A 1 72  ? 8.76605   -26.18915 34.75329  1.000 19.75401  ? 72  ASN H N    1 
ATOM   1047 C CA   . ASN A 1 72  ? 9.65068   -27.31321 35.05084  1.000 21.82354  ? 72  ASN H CA   1 
ATOM   1048 C C    . ASN A 1 72  ? 10.65302  -26.82501 36.08664  1.000 20.70179  ? 72  ASN H C    1 
ATOM   1049 O O    . ASN A 1 72  ? 11.54071  -26.02285 35.76494  1.000 21.09058  ? 72  ASN H O    1 
ATOM   1050 C CB   . ASN A 1 72  ? 10.34617  -27.80068 33.78228  1.000 23.40074  ? 72  ASN H CB   1 
ATOM   1051 C CG   . ASN A 1 72  ? 11.20202  -29.02966 34.01208  1.000 26.03796  ? 72  ASN H CG   1 
ATOM   1052 O OD1  . ASN A 1 72  ? 11.82993  -29.18714 35.05875  1.000 26.76536  ? 72  ASN H OD1  1 
ATOM   1053 N ND2  . ASN A 1 72  ? 11.23954  -29.90370 33.01938  1.000 28.44278  ? 72  ASN H ND2  1 
ATOM   1054 H H    . ASN A 1 72  ? 9.19330   -25.50135 34.46347  1.000 23.71165  ? 72  ASN H H    1 
ATOM   1055 H HA   . ASN A 1 72  ? 9.15086   -28.05731 35.42150  1.000 26.19508  ? 72  ASN H HA   1 
ATOM   1056 H HB2  . ASN A 1 72  ? 9.67359   -28.02425 33.12004  1.000 28.08773  ? 72  ASN H HB2  1 
ATOM   1057 H HB3  . ASN A 1 72  ? 10.92057  -27.09481 33.44655  1.000 28.08773  ? 72  ASN H HB3  1 
ATOM   1058 H HD21 . ASN A 1 72  ? 11.70942  -30.62004 33.09470  1.000 34.13817  ? 72  ASN H HD21 1 
ATOM   1059 H HD22 . ASN A 1 72  ? 10.79403  -29.75545 32.29886  1.000 34.13817  ? 72  ASN H HD22 1 
ATOM   1060 N N    . THR A 1 73  ? 10.49136  -27.29125 37.33107  1.000 21.05886  ? 73  THR H N    1 
ATOM   1061 C CA   . THR A 1 73  ? 11.30216  -26.78610 38.43453  1.000 23.91676  ? 73  THR H CA   1 
ATOM   1062 C C    . THR A 1 73  ? 12.75134  -27.24973 38.34159  1.000 26.83242  ? 73  THR H C    1 
ATOM   1063 O O    . THR A 1 73  ? 13.66103  -26.50417 38.72380  1.000 29.57891  ? 73  THR H O    1 
ATOM   1064 C CB   . THR A 1 73  ? 10.69849  -27.22186 39.77251  1.000 28.40961  ? 73  THR H CB   1 
ATOM   1065 O OG1  . THR A 1 73  ? 10.61594  -28.65085 39.81380  1.000 31.28867  ? 73  THR H OG1  1 
ATOM   1066 C CG2  . THR A 1 73  ? 9.30019   -26.63045 39.95458  1.000 32.89309  ? 73  THR H CG2  1 
ATOM   1067 H H    . THR A 1 73  ? 9.92274   -27.89529 37.55781  1.000 25.27747  ? 73  THR H H    1 
ATOM   1068 H HA   . THR A 1 73  ? 11.29689  -25.81684 38.39690  1.000 28.70695  ? 73  THR H HA   1 
ATOM   1069 H HB   . THR A 1 73  ? 11.25892  -26.90487 40.49800  1.000 34.09837  ? 73  THR H HB   1 
ATOM   1070 H HG1  . THR A 1 73  ? 10.27908  -28.89823 40.54244  1.000 37.55324  ? 73  THR H HG1  1 
ATOM   1071 H HG21 . THR A 1 73  ? 8.94302   -26.88362 40.82016  1.000 39.47854  ? 73  THR H HG21 1 
ATOM   1072 H HG22 . THR A 1 73  ? 9.33974   -25.66273 39.90117  1.000 39.47854  ? 73  THR H HG22 1 
ATOM   1073 H HG23 . THR A 1 73  ? 8.70767   -26.96005 39.26091  1.000 39.47854  ? 73  THR H HG23 1 
ATOM   1074 N N    . ASN A 1 74  ? 12.99683  -28.45881 37.83604  1.000 29.79873  ? 74  ASN H N    1 
ATOM   1075 C CA   . ASN A 1 74  ? 14.37662  -28.91310 37.69370  1.000 30.70807  ? 74  ASN H CA   1 
ATOM   1076 C C    . ASN A 1 74  ? 15.13347  -28.05661 36.68583  1.000 27.39227  ? 74  ASN H C    1 
ATOM   1077 O O    . ASN A 1 74  ? 16.22167  -27.54606 36.97669  1.000 27.35573  ? 74  ASN H O    1 
ATOM   1078 C CB   . ASN A 1 74  ? 14.42239  -30.37994 37.27599  1.000 36.14760  ? 74  ASN H CB   1 
ATOM   1079 C CG   . ASN A 1 74  ? 15.84788  -30.87289 37.06837  1.000 44.43646  ? 74  ASN H CG   1 
ATOM   1080 O OD1  . ASN A 1 74  ? 16.20941  -31.33959 35.98746  1.000 47.02242  ? 74  ASN H OD1  1 
ATOM   1081 N ND2  . ASN A 1 74  ? 16.67456  -30.73408 38.09995  1.000 35.54213  ? 74  ASN H ND2  1 
ATOM   1082 H H    . ASN A 1 74  ? 12.39867  -29.01907 37.57544  1.000 35.76530  ? 74  ASN H H    1 
ATOM   1083 H HA   . ASN A 1 74  ? 14.81096  -28.83476 38.55748  1.000 36.85652  ? 74  ASN H HA   1 
ATOM   1084 H HB2  . ASN A 1 74  ? 14.01287  -30.92136 37.96885  1.000 43.38395  ? 74  ASN H HB2  1 
ATOM   1085 H HB3  . ASN A 1 74  ? 13.94004  -30.48868 36.44147  1.000 43.38395  ? 74  ASN H HB3  1 
ATOM   1086 H HD21 . ASN A 1 74  ? 17.49098  -30.99649 38.03507  1.000 42.65740  ? 74  ASN H HD21 1 
ATOM   1087 H HD22 . ASN A 1 74  ? 16.39301  -30.38187 38.83226  1.000 42.65740  ? 74  ASN H HD22 1 
ATOM   1088 N N    . GLU A 1 75  ? 14.57153  -27.88671 35.49124  1.000 23.74414  ? 75  GLU H N    1 
ATOM   1089 C CA   . GLU A 1 75  ? 15.21208  -27.05967 34.47974  1.000 20.48067  ? 75  GLU H CA   1 
ATOM   1090 C C    . GLU A 1 75  ? 15.04927  -25.57214 34.74578  1.000 21.12908  ? 75  GLU H C    1 
ATOM   1091 O O    . GLU A 1 75  ? 15.73945  -24.76881 34.10477  1.000 19.35012  ? 75  GLU H O    1 
ATOM   1092 C CB   . GLU A 1 75  ? 14.65613  -27.40282 33.09891  1.000 24.24214  ? 75  GLU H CB   1 
ATOM   1093 C CG   . GLU A 1 75  ? 14.96756  -28.82161 32.66733  1.000 32.00600  ? 75  GLU H CG   1 
ATOM   1094 C CD   . GLU A 1 75  ? 15.07310  -28.94802 31.16583  1.000 52.16937  ? 75  GLU H CD   1 
ATOM   1095 O OE1  . GLU A 1 75  ? 16.11951  -28.54466 30.60908  1.000 53.84784  ? 75  GLU H OE1  1 
ATOM   1096 O OE2  . GLU A 1 75  ? 14.10497  -29.43506 30.54336  1.000 48.55662  ? 75  GLU H OE2  1 
ATOM   1097 H H    . GLU A 1 75  ? 13.82563  -28.23794 35.24654  1.000 28.49980  ? 75  GLU H H    1 
ATOM   1098 H HA   . GLU A 1 75  ? 16.16246  -27.25362 34.47197  1.000 24.58364  ? 75  GLU H HA   1 
ATOM   1099 H HB2  . GLU A 1 75  ? 13.69170  -27.30005 33.11409  1.000 29.09740  ? 75  GLU H HB2  1 
ATOM   1100 H HB3  . GLU A 1 75  ? 15.04377  -26.79985 32.44542  1.000 29.09740  ? 75  GLU H HB3  1 
ATOM   1101 H HG2  . GLU A 1 75  ? 15.81429  -29.09389 33.05440  1.000 38.41403  ? 75  GLU H HG2  1 
ATOM   1102 H HG3  . GLU A 1 75  ? 14.25911  -29.41012 32.97171  1.000 38.41403  ? 75  GLU H HG3  1 
ATOM   1103 N N    . ASN A 1 76  ? 14.17065  -25.19599 35.68062  1.000 21.76184  ? 76  ASN H N    1 
ATOM   1104 C CA   . ASN A 1 76  ? 13.91848  -23.79787 36.02755  1.000 16.59503  ? 76  ASN H CA   1 
ATOM   1105 C C    . ASN A 1 76  ? 13.35480  -23.02994 34.83228  1.000 18.76439  ? 76  ASN H C    1 
ATOM   1106 O O    . ASN A 1 76  ? 13.82249  -21.94265 34.48945  1.000 18.46254  ? 76  ASN H O    1 
ATOM   1107 C CB   . ASN A 1 76  ? 15.18874  -23.13076 36.55354  1.000 21.50070  ? 76  ASN H CB   1 
ATOM   1108 C CG   . ASN A 1 76  ? 14.90279  -22.01522 37.54928  1.000 18.39827  ? 76  ASN H CG   1 
ATOM   1109 O OD1  . ASN A 1 76  ? 13.94839  -22.08180 38.32917  1.000 21.16975  ? 76  ASN H OD1  1 
ATOM   1110 N ND2  . ASN A 1 76  ? 15.74934  -20.99566 37.54527  1.000 22.43412  ? 76  ASN H ND2  1 
ATOM   1111 H H    . ASN A 1 76  ? 13.69685  -25.74850 36.13871  1.000 26.12105  ? 76  ASN H H    1 
ATOM   1112 H HA   . ASN A 1 76  ? 13.25148  -23.77223 36.73136  1.000 19.92087  ? 76  ASN H HA   1 
ATOM   1113 H HB2  . ASN A 1 76  ? 15.73400  -23.79763 36.99948  1.000 25.80768  ? 76  ASN H HB2  1 
ATOM   1114 H HB3  . ASN A 1 76  ? 15.67653  -22.74831 35.80742  1.000 25.80768  ? 76  ASN H HB3  1 
ATOM   1115 H HD21 . ASN A 1 76  ? 15.63381  -20.33869 38.08807  1.000 26.92778  ? 76  ASN H HD21 1 
ATOM   1116 H HD22 . ASN A 1 76  ? 16.41425  -20.99099 36.99986  1.000 26.92778  ? 76  ASN H HD22 1 
ATOM   1117 N N    . THR A 1 77  ? 12.33044  -23.60512 34.19774  1.000 17.67726  ? 77  THR H N    1 
ATOM   1118 C CA   . THR A 1 77  ? 11.76968  -23.04765 32.97349  1.000 17.30658  ? 77  THR H CA   1 
ATOM   1119 C C    . THR A 1 77  ? 10.25862  -22.89894 33.09215  1.000 19.45761  ? 77  THR H C    1 
ATOM   1120 O O    . THR A 1 77  ? 9.60835   -23.57852 33.88492  1.000 17.36458  ? 77  THR H O    1 
ATOM   1121 C CB   . THR A 1 77  ? 12.05719  -23.93313 31.74672  1.000 20.04060  ? 77  THR H CB   1 
ATOM   1122 O OG1  . THR A 1 77  ? 11.46639  -25.22015 31.95831  1.000 19.65591  ? 77  THR H OG1  1 
ATOM   1123 C CG2  . THR A 1 77  ? 13.55596  -24.08682 31.51028  1.000 23.99141  ? 77  THR H CG2  1 
ATOM   1124 H H    . THR A 1 77  ? 11.94249  -24.32551 34.46258  1.000 21.21955  ? 77  THR H H    1 
ATOM   1125 H HA   . THR A 1 77  ? 12.16721  -22.17209 32.84595  1.000 20.77472  ? 77  THR H HA   1 
ATOM   1126 H HB   . THR A 1 77  ? 11.68141  -23.52105 30.95308  1.000 24.05555  ? 77  THR H HB   1 
ATOM   1127 H HG1  . THR A 1 77  ? 11.60956  -25.71463 31.29454  1.000 23.59393  ? 77  THR H HG1  1 
ATOM   1128 H HG21 . THR A 1 77  ? 13.71360  -24.63998 30.72921  1.000 28.79653  ? 77  THR H HG21 1 
ATOM   1129 H HG22 . THR A 1 77  ? 13.96009  -23.21680 31.36663  1.000 28.79653  ? 77  THR H HG22 1 
ATOM   1130 H HG23 . THR A 1 77  ? 13.97230  -24.50399 32.28069  1.000 28.79653  ? 77  THR H HG23 1 
ATOM   1131 N N    . VAL A 1 78  ? 9.71326   -22.00899 32.26554  1.000 18.89968  ? 78  VAL H N    1 
ATOM   1132 C CA   . VAL A 1 78  ? 8.27230   -21.86377 32.07910  1.000 16.78456  ? 78  VAL H CA   1 
ATOM   1133 C C    . VAL A 1 78  ? 7.99847   -21.93790 30.58517  1.000 17.27422  ? 78  VAL H C    1 
ATOM   1134 O O    . VAL A 1 78  ? 8.76962   -21.41089 29.77836  1.000 17.11401  ? 78  VAL H O    1 
ATOM   1135 C CB   . VAL A 1 78  ? 7.73125   -20.54827 32.68290  1.000 17.24745  ? 78  VAL H CB   1 
ATOM   1136 C CG1  . VAL A 1 78  ? 8.37863   -19.33898 32.02748  1.000 20.64263  ? 78  VAL H CG1  1 
ATOM   1137 C CG2  . VAL A 1 78  ? 6.21275   -20.48163 32.54655  1.000 18.69439  ? 78  VAL H CG2  1 
ATOM   1138 H H    . VAL A 1 78  ? 10.17257  -21.46140 31.78723  1.000 22.68644  ? 78  VAL H H    1 
ATOM   1139 H HA   . VAL A 1 78  ? 7.80815   -22.59101 32.52249  1.000 20.14831  ? 78  VAL H HA   1 
ATOM   1140 H HB   . VAL A 1 78  ? 7.95499   -20.52969 33.62657  1.000 20.70377  ? 78  VAL H HB   1 
ATOM   1141 H HG11 . VAL A 1 78  ? 8.11973   -18.54019 32.51307  1.000 24.77799  ? 78  VAL H HG11 1 
ATOM   1142 H HG12 . VAL A 1 78  ? 9.34258   -19.44397 32.05340  1.000 24.77799  ? 78  VAL H HG12 1 
ATOM   1143 H HG13 . VAL A 1 78  ? 8.07703   -19.27914 31.10750  1.000 24.77799  ? 78  VAL H HG13 1 
ATOM   1144 H HG21 . VAL A 1 78  ? 5.88746   -19.69849 33.01748  1.000 22.44010  ? 78  VAL H HG21 1 
ATOM   1145 H HG22 . VAL A 1 78  ? 5.98246   -20.42154 31.60620  1.000 22.44010  ? 78  VAL H HG22 1 
ATOM   1146 H HG23 . VAL A 1 78  ? 5.82564   -21.28350 32.93132  1.000 22.44010  ? 78  VAL H HG23 1 
ATOM   1147 N N    . THR A 1 79  ? 6.90670   -22.59782 30.21362  1.000 14.56055  ? 79  THR H N    1 
ATOM   1148 C CA   . THR A 1 79  ? 6.65099   -22.95826 28.82973  1.000 14.95341  ? 79  THR H CA   1 
ATOM   1149 C C    . THR A 1 79  ? 5.21427   -22.66018 28.43771  1.000 12.41134  ? 79  THR H C    1 
ATOM   1150 O O    . THR A 1 79  ? 4.28010   -22.92245 29.20127  1.000 15.19938  ? 79  THR H O    1 
ATOM   1151 C CB   . THR A 1 79  ? 6.94513   -24.45095 28.60831  1.000 19.45885  ? 79  THR H CB   1 
ATOM   1152 O OG1  . THR A 1 79  ? 8.33749   -24.69534 28.83407  1.000 22.07409  ? 79  THR H OG1  1 
ATOM   1153 C CG2  . THR A 1 79  ? 6.55529   -24.88379 27.20913  1.000 23.74611  ? 79  THR H CG2  1 
ATOM   1154 H H    . THR A 1 79  ? 6.28982   -22.85116 30.75665  1.000 17.47949  ? 79  THR H H    1 
ATOM   1155 H HA   . THR A 1 79  ? 7.21480   -22.41824 28.25406  1.000 17.95092  ? 79  THR H HA   1 
ATOM   1156 H HB   . THR A 1 79  ? 6.42167   -24.98210 29.22861  1.000 23.35746  ? 79  THR H HB   1 
ATOM   1157 H HG1  . THR A 1 79  ? 8.50850   -25.50973 28.71954  1.000 26.49574  ? 79  THR H HG1  1 
ATOM   1158 H HG21 . THR A 1 79  ? 6.98517   -25.72536 26.99034  1.000 28.50216  ? 79  THR H HG21 1 
ATOM   1159 H HG22 . THR A 1 79  ? 5.59362   -24.99757 27.15291  1.000 28.50216  ? 79  THR H HG22 1 
ATOM   1160 H HG23 . THR A 1 79  ? 6.83106   -24.21271 26.56532  1.000 28.50216  ? 79  THR H HG23 1 
ATOM   1161 N N    . LEU A 1 80  ? 5.05832   -22.13410 27.22512  1.000 14.75245  ? 80  LEU H N    1 
ATOM   1162 C CA   . LEU A 1 80  ? 3.77078   -21.91706 26.58953  1.000 13.29609  ? 80  LEU H CA   1 
ATOM   1163 C C    . LEU A 1 80  ? 3.64905   -22.85968 25.40223  1.000 15.59981  ? 80  LEU H C    1 
ATOM   1164 O O    . LEU A 1 80  ? 4.52750   -22.88889 24.53429  1.000 15.33693  ? 80  LEU H O    1 
ATOM   1165 C CB   . LEU A 1 80  ? 3.62247   -20.46653 26.11823  1.000 13.92094  ? 80  LEU H CB   1 
ATOM   1166 C CG   . LEU A 1 80  ? 2.40915   -20.17908 25.22828  1.000 15.92554  ? 80  LEU H CG   1 
ATOM   1167 C CD1  . LEU A 1 80  ? 1.13009   -20.34679 26.02204  1.000 17.22498  ? 80  LEU H CD1  1 
ATOM   1168 C CD2  . LEU A 1 80  ? 2.47523   -18.78706 24.61025  1.000 17.15281  ? 80  LEU H CD2  1 
ATOM   1169 H H    . LEU A 1 80  ? 5.71718   -21.88488 26.73177  1.000 17.70977  ? 80  LEU H H    1 
ATOM   1170 H HA   . LEU A 1 80  ? 3.05892   -22.10447 27.22122  1.000 15.96214  ? 80  LEU H HA   1 
ATOM   1171 H HB2  . LEU A 1 80  ? 3.54711   -19.89894 26.90121  1.000 16.71196  ? 80  LEU H HB2  1 
ATOM   1172 H HB3  . LEU A 1 80  ? 4.41483   -20.22927 25.61150  1.000 16.71196  ? 80  LEU H HB3  1 
ATOM   1173 H HG   . LEU A 1 80  ? 2.41020   -20.81519 24.49598  1.000 19.11748  ? 80  LEU H HG   1 
ATOM   1174 H HD11 . LEU A 1 80  ? 0.37421   -20.14030 25.45028  1.000 20.67681  ? 80  LEU H HD11 1 
ATOM   1175 H HD12 . LEU A 1 80  ? 1.06912   -21.26368 26.33269  1.000 20.67681  ? 80  LEU H HD12 1 
ATOM   1176 H HD13 . LEU A 1 80  ? 1.14689   -19.74128 26.77966  1.000 20.67681  ? 80  LEU H HD13 1 
ATOM   1177 H HD21 . LEU A 1 80  ? 1.69190   -18.65070 24.05465  1.000 20.59020  ? 80  LEU H HD21 1 
ATOM   1178 H HD22 . LEU A 1 80  ? 2.49596   -18.12683 25.32057  1.000 20.59020  ? 80  LEU H HD22 1 
ATOM   1179 H HD23 . LEU A 1 80  ? 3.27891   -18.71859 24.07144  1.000 20.59020  ? 80  LEU H HD23 1 
ATOM   1180 N N    . LYS A 1 81  ? 2.56143   -23.61964 25.36618  1.000 13.87558  ? 81  LYS H N    1 
ATOM   1181 C CA   . LYS A 1 81  ? 2.18533   -24.40054 24.20378  1.000 12.49318  ? 81  LYS H CA   1 
ATOM   1182 C C    . LYS A 1 81  ? 0.84277   -23.88813 23.71179  1.000 16.64220  ? 81  LYS H C    1 
ATOM   1183 O O    . LYS A 1 81  ? -0.06459  -23.65130 24.51502  1.000 16.54167  ? 81  LYS H O    1 
ATOM   1184 C CB   . LYS A 1 81  ? 2.09914   -25.89277 24.52649  1.000 16.13568  ? 81  LYS H CB   1 
ATOM   1185 C CG   . LYS A 1 81  ? 3.41457   -26.49626 24.97969  1.000 25.13847  ? 81  LYS H CG   1 
ATOM   1186 C CD   . LYS A 1 81  ? 3.25554   -27.96928 25.32459  1.000 35.49733  ? 81  LYS H CD   1 
ATOM   1187 C CE   . LYS A 1 81  ? 4.33581   -28.42785 26.28882  1.000 42.71205  ? 81  LYS H CE   1 
ATOM   1188 N NZ   . LYS A 1 81  ? 4.08372   -29.81108 26.77383  1.000 53.99908  ? 81  LYS H NZ   1 
ATOM   1189 H H    . LYS A 1 81  ? 2.01256   -23.69878 26.02350  1.000 16.65753  ? 81  LYS H H    1 
ATOM   1190 H HA   . LYS A 1 81  ? 2.84843   -24.29405 23.50388  1.000 14.99865  ? 81  LYS H HA   1 
ATOM   1191 H HB2  . LYS A 1 81  ? 1.45335   -26.02102 25.23882  1.000 19.36965  ? 81  LYS H HB2  1 
ATOM   1192 H HB3  . LYS A 1 81  ? 1.81381   -26.36804 23.73049  1.000 19.36965  ? 81  LYS H HB3  1 
ATOM   1193 H HG2  . LYS A 1 81  ? 4.06771   -26.41776 24.26684  1.000 30.17300  ? 81  LYS H HG2  1 
ATOM   1194 H HG3  . LYS A 1 81  ? 3.72815   -26.02917 25.76988  1.000 30.17300  ? 81  LYS H HG3  1 
ATOM   1195 H HD2  . LYS A 1 81  ? 2.39185   -28.11105 25.74273  1.000 42.60363  ? 81  LYS H HD2  1 
ATOM   1196 H HD3  . LYS A 1 81  ? 3.32309   -28.49909 24.51488  1.000 42.60363  ? 81  LYS H HD3  1 
ATOM   1197 H HE2  . LYS A 1 81  ? 5.19478   -28.41456 25.83837  1.000 51.26129  ? 81  LYS H HE2  1 
ATOM   1198 H HE3  . LYS A 1 81  ? 4.35426   -27.83445 27.05593  1.000 51.26129  ? 81  LYS H HE3  1 
ATOM   1199 H HZ1  . LYS A 1 81  ? 4.72450   -30.05640 27.34068  1.000 64.80573  ? 81  LYS H HZ1  1 
ATOM   1200 H HZ2  . LYS A 1 81  ? 3.29867   -29.84889 27.19141  1.000 64.80573  ? 81  LYS H HZ2  1 
ATOM   1201 H HZ3  . LYS A 1 81  ? 4.07321   -30.37722 26.08720  1.000 64.80573  ? 81  LYS H HZ3  1 
ATOM   1202 N N    . MET A 1 82  ? 0.73164   -23.68783 22.40576  1.000 14.90017  ? 82  MET H N    1 
ATOM   1203 C CA   . MET A 1 82  ? -0.53502  -23.33303 21.78268  1.000 14.27576  ? 82  MET H CA   1 
ATOM   1204 C C    . MET A 1 82  ? -0.71506  -24.17504 20.52826  1.000 21.53089  ? 82  MET H C    1 
ATOM   1205 O O    . MET A 1 82  ? 0.22060   -24.31806 19.74565  1.000 21.02410  ? 82  MET H O    1 
ATOM   1206 C CB   . MET A 1 82  ? -0.59041  -21.84656 21.41556  1.000 22.11225  ? 82  MET H CB   1 
ATOM   1207 C CG   . MET A 1 82  ? -0.70343  -20.90682 22.58918  1.000 24.63381  ? 82  MET H CG   1 
ATOM   1208 S SD   . MET A 1 82  ? -0.80062  -19.18136 22.06906  1.000 31.85907  ? 82  MET H SD   1 
ATOM   1209 C CE   . MET A 1 82  ? -2.25982  -19.21031 21.02243  1.000 17.67964  ? 82  MET H CE   1 
ATOM   1210 H H    . MET A 1 82  ? 1.38597   -23.75267 21.85147  1.000 17.88703  ? 82  MET H H    1 
ATOM   1211 H HA   . MET A 1 82  ? -1.25877  -23.50865 22.40416  1.000 17.13775  ? 82  MET H HA   1 
ATOM   1212 H HB2  . MET A 1 82  ? 0.22135   -21.61783 20.93637  1.000 26.54153  ? 82  MET H HB2  1 
ATOM   1213 H HB3  . MET A 1 82  ? -1.36331  -21.69859 20.84843  1.000 26.54153  ? 82  MET H HB3  1 
ATOM   1214 H HG2  . MET A 1 82  ? -1.50672  -21.11785 23.09028  1.000 29.56740  ? 82  MET H HG2  1 
ATOM   1215 H HG3  . MET A 1 82  ? 0.07735   -21.00893 23.15562  1.000 29.56740  ? 82  MET H HG3  1 
ATOM   1216 H HE1  . MET A 1 82  ? -2.53939  -18.29856 20.84508  1.000 21.22241  ? 82  MET H HE1  1 
ATOM   1217 H HE2  . MET A 1 82  ? -2.04229  -19.65751 20.18961  1.000 21.22241  ? 82  MET H HE2  1 
ATOM   1218 H HE3  . MET A 1 82  ? -2.96754  -19.69013 21.48048  1.000 21.22241  ? 82  MET H HE3  1 
ATOM   1219 N N    . ASN A 1 83  A -1.90873  -24.73026 20.32841  1.000 22.50168  ? 82  ASN H N    1 
ATOM   1220 C CA   . ASN A 1 83  A -2.17216  -25.55645 19.15448  1.000 23.46072  ? 82  ASN H CA   1 
ATOM   1221 C C    . ASN A 1 83  A -3.27034  -24.92928 18.30084  1.000 22.34003  ? 82  ASN H C    1 
ATOM   1222 O O    . ASN A 1 83  A -3.87359  -23.91960 18.66649  1.000 20.95228  ? 82  ASN H O    1 
ATOM   1223 C CB   . ASN A 1 83  A -2.54454  -26.98740 19.56091  1.000 23.19580  ? 82  ASN H CB   1 
ATOM   1224 C CG   . ASN A 1 83  A -3.74385  -27.04299 20.46541  1.000 36.71493  ? 82  ASN H CG   1 
ATOM   1225 O OD1  . ASN A 1 83  A -4.76931  -26.40732 20.20237  1.000 39.18232  ? 82  ASN H OD1  1 
ATOM   1226 N ND2  . ASN A 1 83  A -3.62697  -27.80397 21.55088  1.000 38.94254  ? 82  ASN H ND2  1 
ATOM   1227 H H    . ASN A 1 83  A -2.57984  -24.64204 20.85891  1.000 27.00885  ? 82  ASN H H    1 
ATOM   1228 H HA   . ASN A 1 83  A -1.37060  -25.59924 18.60991  1.000 28.15969  ? 82  ASN H HA   1 
ATOM   1229 H HB2  . ASN A 1 83  A -2.74717  -27.49990 18.76267  1.000 27.84179  ? 82  ASN H HB2  1 
ATOM   1230 H HB3  . ASN A 1 83  A -1.79602  -27.38725 20.03075  1.000 27.84179  ? 82  ASN H HB3  1 
ATOM   1231 H HD21 . ASN A 1 83  A -4.28383  -27.87078 22.10195  1.000 46.73789  ? 82  ASN H HD21 1 
ATOM   1232 H HD22 . ASN A 1 83  A -2.89459  -28.22894 21.70128  1.000 46.73789  ? 82  ASN H HD22 1 
ATOM   1233 N N    . SER A 1 84  B -3.50815  -25.53555 17.13600  1.000 19.82663  ? 82  SER H N    1 
ATOM   1234 C CA   . SER A 1 84  B -4.47390  -25.02857 16.15675  1.000 16.31838  ? 82  SER H CA   1 
ATOM   1235 C C    . SER A 1 84  B -4.23820  -23.54871 15.86026  1.000 18.87366  ? 82  SER H C    1 
ATOM   1236 O O    . SER A 1 84  B -5.14574  -22.71971 15.94201  1.000 16.49414  ? 82  SER H O    1 
ATOM   1237 C CB   . SER A 1 84  B -5.90753  -25.26217 16.63882  1.000 18.57066  ? 82  SER H CB   1 
ATOM   1238 O OG   . SER A 1 84  B -6.06496  -26.59270 17.09977  1.000 27.76034  ? 82  SER H OG   1 
ATOM   1239 H H    . SER A 1 84  B -3.11459  -26.25749 16.88399  1.000 23.79879  ? 82  SER H H    1 
ATOM   1240 H HA   . SER A 1 84  B -4.34641  -25.51576 15.32771  1.000 19.58888  ? 82  SER H HA   1 
ATOM   1241 H HB2  . SER A 1 84  B -6.10161  -24.64966 17.36551  1.000 22.29162  ? 82  SER H HB2  1 
ATOM   1242 H HB3  . SER A 1 84  B -6.51915  -25.10726 15.90206  1.000 22.29162  ? 82  SER H HB3  1 
ATOM   1243 H HG   . SER A 1 84  B -6.82759  -26.69130 17.43783  1.000 33.31924  ? 82  SER H HG   1 
ATOM   1244 N N    . LEU A 1 85  C -3.00287  -23.21831 15.48820  1.000 18.30208  ? 82  LEU H N    1 
ATOM   1245 C CA   . LEU A 1 85  C -2.65517  -21.82705 15.23584  1.000 18.53911  ? 82  LEU H CA   1 
ATOM   1246 C C    . LEU A 1 85  C -3.23132  -21.33981 13.91210  1.000 19.41719  ? 82  LEU H C    1 
ATOM   1247 O O    . LEU A 1 85  C -3.29795  -22.08120 12.92670  1.000 19.93432  ? 82  LEU H O    1 
ATOM   1248 C CB   . LEU A 1 85  C -1.13690  -21.64451 15.22900  1.000 23.23020  ? 82  LEU H CB   1 
ATOM   1249 C CG   . LEU A 1 85  C -0.42925  -21.77479 16.57973  1.000 21.49600  ? 82  LEU H CG   1 
ATOM   1250 C CD1  . LEU A 1 85  C 1.04195   -21.43670 16.43707  1.000 25.71176  ? 82  LEU H CD1  1 
ATOM   1251 C CD2  . LEU A 1 85  C -1.07294  -20.87681 17.62505  1.000 23.20073  ? 82  LEU H CD2  1 
ATOM   1252 H H    . LEU A 1 85  C -2.35727  -23.77543 15.37676  1.000 21.96933  ? 82  LEU H H    1 
ATOM   1253 H HA   . LEU A 1 85  C -3.03086  -21.28472 15.94693  1.000 22.25376  ? 82  LEU H HA   1 
ATOM   1254 H HB2  . LEU A 1 85  C -0.75595  -22.31566 14.64134  1.000 27.88308  ? 82  LEU H HB2  1 
ATOM   1255 H HB3  . LEU A 1 85  C -0.94222  -20.75705 14.88926  1.000 27.88308  ? 82  LEU H HB3  1 
ATOM   1256 H HG   . LEU A 1 85  C -0.51082  -22.69218 16.88411  1.000 25.80203  ? 82  LEU H HG   1 
ATOM   1257 H HD11 . LEU A 1 85  C 1.48019   -21.56636 17.29266  1.000 30.86095  ? 82  LEU H HD11 1 
ATOM   1258 H HD12 . LEU A 1 85  C 1.43710   -22.02089 15.77113  1.000 30.86095  ? 82  LEU H HD12 1 
ATOM   1259 H HD13 . LEU A 1 85  C 1.12780   -20.51160 16.15829  1.000 30.86095  ? 82  LEU H HD13 1 
ATOM   1260 H HD21 . LEU A 1 85  C -0.47999  -20.80676 18.38951  1.000 27.84771  ? 82  LEU H HD21 1 
ATOM   1261 H HD22 . LEU A 1 85  C -1.22072  -19.99906 17.23953  1.000 27.84771  ? 82  LEU H HD22 1 
ATOM   1262 H HD23 . LEU A 1 85  C -1.91906  -21.26526 17.89723  1.000 27.84771  ? 82  LEU H HD23 1 
ATOM   1263 N N    . ARG A 1 86  ? -3.62290  -20.07199 13.89452  1.000 16.72974  ? 83  ARG H N    1 
ATOM   1264 C CA   . ARG A 1 86  ? -4.17310  -19.39851 12.73108  1.000 18.84537  ? 83  ARG H CA   1 
ATOM   1265 C C    . ARG A 1 86  ? -3.30252  -18.19606 12.39358  1.000 19.12921  ? 83  ARG H C    1 
ATOM   1266 O O    . ARG A 1 86  ? -2.44539  -17.78553 13.17517  1.000 17.86271  ? 83  ARG H O    1 
ATOM   1267 C CB   . ARG A 1 86  ? -5.61736  -18.96201 12.99227  1.000 23.59988  ? 83  ARG H CB   1 
ATOM   1268 C CG   . ARG A 1 86  ? -6.53557  -20.11639 13.36288  1.000 29.75404  ? 83  ARG H CG   1 
ATOM   1269 C CD   . ARG A 1 86  ? -7.87839  -19.62472 13.85624  1.000 29.91861  ? 83  ARG H CD   1 
ATOM   1270 N NE   . ARG A 1 86  ? -8.52448  -18.75176 12.88658  1.000 41.60243  ? 83  ARG H NE   1 
ATOM   1271 C CZ   . ARG A 1 86  ? -9.72765  -18.22032 13.04600  1.000 48.70971  ? 83  ARG H CZ   1 
ATOM   1272 N NH1  . ARG A 1 86  ? -10.45498 -18.47032 14.12342  1.000 55.93428  ? 83  ARG H NH1  1 
ATOM   1273 N NH2  . ARG A 1 86  ? -10.21411 -17.42075 12.10047  1.000 46.67694  ? 83  ARG H NH2  1 
ATOM   1274 H H    . ARG A 1 86  ? -3.57629  -19.55663 14.58142  1.000 20.08252  ? 83  ARG H H    1 
ATOM   1275 H HA   . ARG A 1 86  ? -4.17411  -19.99838 11.96882  1.000 22.62127  ? 83  ARG H HA   1 
ATOM   1276 H HB2  . ARG A 1 86  ? -5.62552  -18.32706 13.72553  1.000 28.32669  ? 83  ARG H HB2  1 
ATOM   1277 H HB3  . ARG A 1 86  ? -5.96959  -18.54648 12.18967  1.000 28.32669  ? 83  ARG H HB3  1 
ATOM   1278 H HG2  . ARG A 1 86  ? -6.68330  -20.67228 12.58182  1.000 35.71168  ? 83  ARG H HG2  1 
ATOM   1279 H HG3  . ARG A 1 86  ? -6.12469  -20.63909 14.06918  1.000 35.71168  ? 83  ARG H HG3  1 
ATOM   1280 H HD2  . ARG A 1 86  ? -8.45914  -20.38538 14.01446  1.000 35.90916  ? 83  ARG H HD2  1 
ATOM   1281 H HD3  . ARG A 1 86  ? -7.75387  -19.12566 14.67864  1.000 35.90916  ? 83  ARG H HD3  1 
ATOM   1282 H HE   . ARG A 1 86  ? -8.09717  -18.56909 12.16295  1.000 49.92975  ? 83  ARG H HE   1 
ATOM   1283 H HH11 . ARG A 1 86  ? -10.14866 -18.98743 14.73853  1.000 67.12797  ? 83  ARG H HH11 1 
ATOM   1284 H HH12 . ARG A 1 86  ? -11.23382 -18.11562 14.20827  1.000 67.12797  ? 83  ARG H HH12 1 
ATOM   1285 H HH21 . ARG A 1 86  ? -9.74876  -17.25451 11.39661  1.000 56.01916  ? 83  ARG H HH21 1 
ATOM   1286 H HH22 . ARG A 1 86  ? -10.99391 -17.07014 12.19312  1.000 56.01916  ? 83  ARG H HH22 1 
ATOM   1287 N N    . ALA A 1 87  ? -3.52994  -17.62989 11.20717  1.000 20.83456  ? 84  ALA H N    1 
ATOM   1288 C CA   . ALA A 1 87  ? -2.74861  -16.47043 10.78789  1.000 21.32411  ? 84  ALA H CA   1 
ATOM   1289 C C    . ALA A 1 87  ? -2.84050  -15.35494 11.81600  1.000 22.39670  ? 84  ALA H C    1 
ATOM   1290 O O    . ALA A 1 87  ? -1.85945  -14.64269 12.06930  1.000 22.14351  ? 84  ALA H O    1 
ATOM   1291 C CB   . ALA A 1 87  ? -3.23207  -15.98539 9.42146   1.000 23.43277  ? 84  ALA H CB   1 
ATOM   1292 H H    . ALA A 1 87  ? -4.11905  -17.89310 10.63860  1.000 25.00830  ? 84  ALA H H    1 
ATOM   1293 H HA   . ALA A 1 87  ? -1.81705  -16.72703 10.70282  1.000 25.59576  ? 84  ALA H HA   1 
ATOM   1294 H HB1  . ALA A 1 87  ? -2.71117  -15.21034 9.15903   1.000 28.12616  ? 84  ALA H HB1  1 
ATOM   1295 H HB2  . ALA A 1 87  ? -3.11442  -16.69777 8.77372   1.000 28.12616  ? 84  ALA H HB2  1 
ATOM   1296 H HB3  . ALA A 1 87  ? -4.17030  -15.74740 9.48465   1.000 28.12616  ? 84  ALA H HB3  1 
ATOM   1297 N N    . GLU A 1 88  ? -4.00994  -15.20895 12.43797  1.000 21.46231  ? 85  GLU H N    1 
ATOM   1298 C CA   . GLU A 1 88  ? -4.24816  -14.16737 13.42474  1.000 23.65670  ? 85  GLU H CA   1 
ATOM   1299 C C    . GLU A 1 88  ? -3.41298  -14.34056 14.68189  1.000 24.41783  ? 85  GLU H C    1 
ATOM   1300 O O    . GLU A 1 88  ? -3.32236  -13.39911 15.47753  1.000 23.72515  ? 85  GLU H O    1 
ATOM   1301 C CB   . GLU A 1 88  ? -5.73342  -14.14456 13.79177  1.000 30.58856  ? 85  GLU H CB   1 
ATOM   1302 C CG   . GLU A 1 88  ? -6.64893  -13.57597 12.70362  1.000 44.36380  ? 85  GLU H CG   1 
ATOM   1303 C CD   . GLU A 1 88  ? -6.85358  -14.50471 11.50836  1.000 52.04167  ? 85  GLU H CD   1 
ATOM   1304 O OE1  . GLU A 1 88  ? -6.43197  -15.68304 11.56149  1.000 29.93969  ? 85  GLU H OE1  1 
ATOM   1305 O OE2  . GLU A 1 88  ? -7.44894  -14.04603 10.50714  1.000 54.31241  ? 85  GLU H OE2  1 
ATOM   1306 H H    . GLU A 1 88  ? -4.69359  -15.71242 12.30107  1.000 25.76160  ? 85  GLU H H    1 
ATOM   1307 H HA   . GLU A 1 88  ? -4.01502  -13.30945 13.03677  1.000 28.39487  ? 85  GLU H HA   1 
ATOM   1308 H HB2  . GLU A 1 88  ? -6.02114  -15.05339 13.97104  1.000 36.71310  ? 85  GLU H HB2  1 
ATOM   1309 H HB3  . GLU A 1 88  ? -5.84706  -13.59802 14.58505  1.000 36.71310  ? 85  GLU H HB3  1 
ATOM   1310 H HG2  . GLU A 1 88  ? -7.52042  -13.40038 13.09167  1.000 53.24339  ? 85  GLU H HG2  1 
ATOM   1311 H HG3  . GLU A 1 88  ? -6.26131  -12.75110 12.37160  1.000 53.24339  ? 85  GLU H HG3  1 
ATOM   1312 N N    . ASP A 1 89  ? -2.80853  -15.50618 14.88671  1.000 20.67604  ? 86  ASP H N    1 
ATOM   1313 C CA   . ASP A 1 89  ? -1.94374  -15.74003 16.03526  1.000 19.59553  ? 86  ASP H CA   1 
ATOM   1314 C C    . ASP A 1 89  ? -0.51014  -15.29089 15.78788  1.000 19.76864  ? 86  ASP H C    1 
ATOM   1315 O O    . ASP A 1 89  ? 0.32575   -15.39404 16.69590  1.000 16.21635  ? 86  ASP H O    1 
ATOM   1316 C CB   . ASP A 1 89  ? -1.98065  -17.22649 16.40936  1.000 18.42791  ? 86  ASP H CB   1 
ATOM   1317 C CG   . ASP A 1 89  ? -3.37312  -17.68129 16.83594  1.000 23.93851  ? 86  ASP H CG   1 
ATOM   1318 O OD1  . ASP A 1 89  ? -3.95427  -17.03710 17.73404  1.000 21.29830  ? 86  ASP H OD1  1 
ATOM   1319 O OD2  . ASP A 1 89  ? -3.89578  -18.66413 16.26066  1.000 19.46434  ? 86  ASP H OD2  1 
ATOM   1320 H H    . ASP A 1 89  ? -2.88548  -16.18643 14.36620  1.000 24.81808  ? 86  ASP H H    1 
ATOM   1321 H HA   . ASP A 1 89  ? -2.27463  -15.23802 16.79644  1.000 23.52147  ? 86  ASP H HA   1 
ATOM   1322 H HB2  . ASP A 1 89  ? -1.71276  -17.75445 15.64099  1.000 22.12033  ? 86  ASP H HB2  1 
ATOM   1323 H HB3  . ASP A 1 89  ? -1.37215  -17.38356 17.14826  1.000 22.12033  ? 86  ASP H HB3  1 
ATOM   1324 N N    . THR A 1 90  ? -0.20949  -14.79214 14.58991  1.000 14.69020  ? 87  THR H N    1 
ATOM   1325 C CA   . THR A 1 90  ? 1.10663   -14.22995 14.31207  1.000 15.38615  ? 87  THR H CA   1 
ATOM   1326 C C    . THR A 1 90  ? 1.38665   -13.07792 15.26928  1.000 14.50143  ? 87  THR H C    1 
ATOM   1327 O O    . THR A 1 90  ? 0.58748   -12.14517 15.37905  1.000 16.39785  ? 87  THR H O    1 
ATOM   1328 C CB   . THR A 1 90  ? 1.16858   -13.74807 12.86172  1.000 15.79124  ? 87  THR H CB   1 
ATOM   1329 O OG1  . THR A 1 90  ? 1.11101   -14.87708 11.98144  1.000 19.37646  ? 87  THR H OG1  1 
ATOM   1330 C CG2  . THR A 1 90  ? 2.44328   -12.94664 12.58599  1.000 15.46767  ? 87  THR H CG2  1 
ATOM   1331 H H    . THR A 1 90  ? -0.75058  -14.76793 13.92190  1.000 17.63507  ? 87  THR H H    1 
ATOM   1332 H HA   . THR A 1 90  ? 1.79041   -14.90700 14.43435  1.000 18.47021  ? 87  THR H HA   1 
ATOM   1333 H HB   . THR A 1 90  ? 0.41515   -13.16085 12.69313  1.000 18.95632  ? 87  THR H HB   1 
ATOM   1334 H HG1  . THR A 1 90  ? 0.39423   -15.29840 12.10106  1.000 23.25859  ? 87  THR H HG1  1 
ATOM   1335 H HG21 . THR A 1 90  ? 2.57845   -12.85700 11.62965  1.000 18.56804  ? 87  THR H HG21 1 
ATOM   1336 H HG22 . THR A 1 90  ? 2.37046   -12.06233 12.97789  1.000 18.56804  ? 87  THR H HG22 1 
ATOM   1337 H HG23 . THR A 1 90  ? 3.20973   -13.39952 12.97117  1.000 18.56804  ? 87  THR H HG23 1 
ATOM   1338 N N    . ALA A 1 91  ? 2.51784   -13.14008 15.97168  1.000 15.54517  ? 88  ALA H N    1 
ATOM   1339 C CA   . ALA A 1 91  ? 2.80748   -12.09920 16.95433  1.000 14.32816  ? 88  ALA H CA   1 
ATOM   1340 C C    . ALA A 1 91  ? 4.16148   -12.35876 17.59893  1.000 14.03697  ? 88  ALA H C    1 
ATOM   1341 O O    . ALA A 1 91  ? 4.73665   -13.44223 17.47661  1.000 14.68124  ? 88  ALA H O    1 
ATOM   1342 C CB   . ALA A 1 91  ? 1.72571   -12.03334 18.03763  1.000 17.16583  ? 88  ALA H CB   1 
ATOM   1343 H H    . ALA A 1 91  ? 3.11339   -13.75615 15.89834  1.000 18.66103  ? 88  ALA H H    1 
ATOM   1344 H HA   . ALA A 1 91  ? 2.86373   -11.25152 16.48616  1.000 17.20062  ? 88  ALA H HA   1 
ATOM   1345 H HB1  . ALA A 1 91  ? 2.00682   -11.41183 18.72728  1.000 20.60583  ? 88  ALA H HB1  1 
ATOM   1346 H HB2  . ALA A 1 91  ? 0.89590   -11.72999 17.63726  1.000 20.60583  ? 88  ALA H HB2  1 
ATOM   1347 H HB3  . ALA A 1 91  ? 1.60557   -12.91747 18.41813  1.000 20.60583  ? 88  ALA H HB3  1 
ATOM   1348 N N    . VAL A 1 92  ? 4.65312   -11.34837 18.30908  1.000 13.94977  ? 89  VAL H N    1 
ATOM   1349 C CA   . VAL A 1 92  ? 5.79297   -11.51396 19.20279  1.000 12.10463  ? 89  VAL H CA   1 
ATOM   1350 C C    . VAL A 1 92  ? 5.26197   -11.97464 20.55878  1.000 11.70163  ? 89  VAL H C    1 
ATOM   1351 O O    . VAL A 1 92  ? 4.40101   -11.31847 21.14807  1.000 12.70211  ? 89  VAL H O    1 
ATOM   1352 C CB   . VAL A 1 92  ? 6.59852   -10.21176 19.32858  1.000 15.83674  ? 89  VAL H CB   1 
ATOM   1353 C CG1  . VAL A 1 92  ? 7.73810   -10.38198 20.31748  1.000 15.14996  ? 89  VAL H CG1  1 
ATOM   1354 C CG2  . VAL A 1 92  ? 7.14387   -9.77299  17.96532  1.000 15.50630  ? 89  VAL H CG2  1 
ATOM   1355 H H    . VAL A 1 92  ? 4.33946   -10.54784 18.28972  1.000 16.74656  ? 89  VAL H H    1 
ATOM   1356 H HA   . VAL A 1 92  ? 6.38542   -12.19820 18.85390  1.000 14.53240  ? 89  VAL H HA   1 
ATOM   1357 H HB   . VAL A 1 92  ? 6.00662   -9.51687  19.65676  1.000 19.01093  ? 89  VAL H HB   1 
ATOM   1358 H HG11 . VAL A 1 92  ? 8.32357   -9.61069  20.26046  1.000 18.18679  ? 89  VAL H HG11 1 
ATOM   1359 H HG12 . VAL A 1 92  ? 7.37141   -10.45345 21.21264  1.000 18.18679  ? 89  VAL H HG12 1 
ATOM   1360 H HG13 . VAL A 1 92  ? 8.23038   -11.18800 20.09635  1.000 18.18679  ? 89  VAL H HG13 1 
ATOM   1361 H HG21 . VAL A 1 92  ? 7.67303   -8.96831  18.08099  1.000 18.61440  ? 89  VAL H HG21 1 
ATOM   1362 H HG22 . VAL A 1 92  ? 7.69649   -10.48303 17.60287  1.000 18.61440  ? 89  VAL H HG22 1 
ATOM   1363 H HG23 . VAL A 1 92  ? 6.39925   -9.59639  17.36929  1.000 18.61440  ? 89  VAL H HG23 1 
ATOM   1364 N N    . TYR A 1 93  ? 5.77451   -13.10259 21.04951  1.000 11.93932  ? 90  TYR H N    1 
ATOM   1365 C CA   . TYR A 1 93  ? 5.37373   -13.68740 22.32433  1.000 11.73420  ? 90  TYR H CA   1 
ATOM   1366 C C    . TYR A 1 93  ? 6.45145   -13.43568 23.37865  1.000 16.57078  ? 90  TYR H C    1 
ATOM   1367 O O    . TYR A 1 93  ? 7.64748   -13.57490 23.10167  1.000 13.77359  ? 90  TYR H O    1 
ATOM   1368 C CB   . TYR A 1 93  ? 5.11772   -15.19401 22.16035  1.000 13.62551  ? 90  TYR H CB   1 
ATOM   1369 C CG   . TYR A 1 93  ? 3.87174   -15.50288 21.35224  1.000 14.22389  ? 90  TYR H CG   1 
ATOM   1370 C CD1  . TYR A 1 93  ? 3.84078   -15.32266 19.97414  1.000 14.30150  ? 90  TYR H CD1  1 
ATOM   1371 C CD2  . TYR A 1 93  ? 2.72161   -15.95997 21.97309  1.000 15.15758  ? 90  TYR H CD2  1 
ATOM   1372 C CE1  . TYR A 1 93  ? 2.68215   -15.59311 19.23945  1.000 13.33188  ? 90  TYR H CE1  1 
ATOM   1373 C CE2  . TYR A 1 93  ? 1.57227   -16.22960 21.25620  1.000 13.76462  ? 90  TYR H CE2  1 
ATOM   1374 C CZ   . TYR A 1 93  ? 1.55537   -16.04735 19.89462  1.000 12.91414  ? 90  TYR H CZ   1 
ATOM   1375 O OH   . TYR A 1 93  ? 0.40569   -16.32354 19.19126  1.000 14.73768  ? 90  TYR H OH   1 
ATOM   1376 H H    . TYR A 1 93  ? 6.37832   -13.56308 20.64582  1.000 14.33401  ? 90  TYR H H    1 
ATOM   1377 H HA   . TYR A 1 93  ? 4.55473   -13.27307 22.63812  1.000 14.08787  ? 90  TYR H HA   1 
ATOM   1378 H HB2  . TYR A 1 93  ? 5.87544   -15.59375 21.70540  1.000 16.35744  ? 90  TYR H HB2  1 
ATOM   1379 H HB3  . TYR A 1 93  ? 5.01037   -15.59185 23.03847  1.000 16.35744  ? 90  TYR H HB3  1 
ATOM   1380 H HD1  . TYR A 1 93  ? 4.60154   -15.01786 19.53454  1.000 17.16864  ? 90  TYR H HD1  1 
ATOM   1381 H HD2  . TYR A 1 93  ? 2.72305   -16.08841 22.89418  1.000 18.19593  ? 90  TYR H HD2  1 
ATOM   1382 H HE1  . TYR A 1 93  ? 2.67087   -15.46809 18.31796  1.000 16.00509  ? 90  TYR H HE1  1 
ATOM   1383 H HE2  . TYR A 1 93  ? 0.81075   -16.53414 21.69465  1.000 16.52438  ? 90  TYR H HE2  1 
ATOM   1384 H HH   . TYR A 1 93  ? 0.51808   -16.14941 18.37723  1.000 17.69205  ? 90  TYR H HH   1 
ATOM   1385 N N    . TYR A 1 94  ? 6.01214   -13.03852 24.58354  1.000 14.41512  ? 91  TYR H N    1 
ATOM   1386 C CA   . TYR A 1 94  ? 6.87109   -12.72014 25.71415  1.000 12.25980  ? 91  TYR H CA   1 
ATOM   1387 C C    . TYR A 1 94  ? 6.44116   -13.52798 26.93026  1.000 12.69315  ? 91  TYR H C    1 
ATOM   1388 O O    . TYR A 1 94  ? 5.24502   -13.67961 27.19609  1.000 13.22550  ? 91  TYR H O    1 
ATOM   1389 C CB   . TYR A 1 94  ? 6.79752   -11.23292 26.13221  1.000 12.77989  ? 91  TYR H CB   1 
ATOM   1390 C CG   . TYR A 1 94  ? 7.14405   -10.21972 25.08398  1.000 12.14251  ? 91  TYR H CG   1 
ATOM   1391 C CD1  . TYR A 1 94  ? 6.16278   -9.68001  24.26527  1.000 16.17565  ? 91  TYR H CD1  1 
ATOM   1392 C CD2  . TYR A 1 94  ? 8.44372   -9.77027  24.93396  1.000 14.43877  ? 91  TYR H CD2  1 
ATOM   1393 C CE1  . TYR A 1 94  ? 6.47646   -8.73782  23.31213  1.000 15.78467  ? 91  TYR H CE1  1 
ATOM   1394 C CE2  . TYR A 1 94  ? 8.76687   -8.83035  23.98508  1.000 15.23737  ? 91  TYR H CE2  1 
ATOM   1395 C CZ   . TYR A 1 94  ? 7.78359   -8.31407  23.17854  1.000 15.97510  ? 91  TYR H CZ   1 
ATOM   1396 O OH   . TYR A 1 94  ? 8.11135   -7.37845  22.22689  1.000 19.82970  ? 91  TYR H OH   1 
ATOM   1397 H H    . TYR A 1 94  ? 5.17806   -12.94414 24.77062  1.000 17.30498  ? 91  TYR H H    1 
ATOM   1398 H HA   . TYR A 1 94  ? 7.77882   -12.93847 25.45097  1.000 14.71859  ? 91  TYR H HA   1 
ATOM   1399 H HB2  . TYR A 1 94  ? 5.88952   -11.04591 26.41763  1.000 15.34270  ? 91  TYR H HB2  1 
ATOM   1400 H HB3  . TYR A 1 94  ? 7.41186   -11.09793 26.87063  1.000 15.34270  ? 91  TYR H HB3  1 
ATOM   1401 H HD1  . TYR A 1 94  ? 5.28077   -9.95867  24.36175  1.000 19.41762  ? 91  TYR H HD1  1 
ATOM   1402 H HD2  . TYR A 1 94  ? 9.11093   -10.11045 25.48533  1.000 17.33336  ? 91  TYR H HD2  1 
ATOM   1403 H HE1  . TYR A 1 94  ? 5.81259   -8.38915  22.76203  1.000 18.94844  ? 91  TYR H HE1  1 
ATOM   1404 H HE2  . TYR A 1 94  ? 9.64706   -8.54557  23.88990  1.000 18.29168  ? 91  TYR H HE2  1 
ATOM   1405 H HH   . TYR A 1 94  ? 8.93658   -7.22318  22.24890  1.000 23.80248  ? 91  TYR H HH   1 
ATOM   1406 N N    . CYS A 1 95  ? 7.41888   -14.00941 27.68166  1.000 15.86282  ? 92  CYS H N    1 
ATOM   1407 C CA   . CYS A 1 95  ? 7.21298   -14.46248 29.05030  1.000 11.70468  ? 92  CYS H CA   1 
ATOM   1408 C C    . CYS A 1 95  ? 7.59049   -13.31799 29.97602  1.000 12.79560  ? 92  CYS H C    1 
ATOM   1409 O O    . CYS A 1 95  ? 8.55847   -12.59891 29.71369  1.000 14.52788  ? 92  CYS H O    1 
ATOM   1410 C CB   . CYS A 1 95  ? 8.07060   -15.68287 29.34699  1.000 16.75398  ? 92  CYS H CB   1 
ATOM   1411 S SG   . CYS A 1 95  ? 9.80641   -15.32099 29.02187  0.683 16.41742  ? 92  CYS H SG   1 
ATOM   1412 H H    . CYS A 1 95  ? 8.23289   -14.08625 27.41505  1.000 19.04221  ? 92  CYS H H    1 
ATOM   1413 H HA   . CYS A 1 95  ? 6.28837   -14.71397 29.20111  1.000 14.05245  ? 92  CYS H HA   1 
ATOM   1414 H HB2  . CYS A 1 95  ? 7.97389   -15.92899 30.28025  1.000 20.11161  ? 92  CYS H HB2  1 
ATOM   1415 H HB3  . CYS A 1 95  ? 7.79504   -16.41957 28.77933  1.000 20.11161  ? 92  CYS H HB3  1 
ATOM   1416 N N    . ALA A 1 96  ? 6.82163   -13.13145 31.04658  1.000 14.35755  ? 93  ALA H N    1 
ATOM   1417 C CA   . ALA A 1 96  ? 7.05740   -11.97865 31.90103  1.000 15.65761  ? 93  ALA H CA   1 
ATOM   1418 C C    . ALA A 1 96  ? 6.45434   -12.19595 33.27755  1.000 15.10570  ? 93  ALA H C    1 
ATOM   1419 O O    . ALA A 1 96  ? 5.33879   -12.69735 33.39479  1.000 17.66903  ? 93  ALA H O    1 
ATOM   1420 C CB   . ALA A 1 96  ? 6.44931   -10.70581 31.29666  1.000 16.59568  ? 93  ALA H CB   1 
ATOM   1421 H H    . ALA A 1 96  ? 6.17635   -13.64534 31.28975  1.000 17.23590  ? 93  ALA H H    1 
ATOM   1422 H HA   . ALA A 1 96  ? 8.01679   -11.87771 32.00243  1.000 18.79597  ? 93  ALA H HA   1 
ATOM   1423 H HB1  . ALA A 1 96  ? 6.63904   -9.95628  31.88242  1.000 19.92165  ? 93  ALA H HB1  1 
ATOM   1424 H HB2  . ALA A 1 96  ? 6.84313   -10.55138 30.42375  1.000 19.92165  ? 93  ALA H HB2  1 
ATOM   1425 H HB3  . ALA A 1 96  ? 5.49038   -10.82398 31.21070  1.000 19.92165  ? 93  ALA H HB3  1 
ATOM   1426 N N    . LYS A 1 97  ? 7.18337   -11.79778 34.30982  1.000 12.74541  ? 94  LYS H N    1 
ATOM   1427 C CA   . LYS A 1 97  ? 6.57188   -11.48066 35.59617  1.000 13.05388  ? 94  LYS H CA   1 
ATOM   1428 C C    . LYS A 1 97  ? 6.26961   -9.98743  35.55842  1.000 12.27888  ? 94  LYS H C    1 
ATOM   1429 O O    . LYS A 1 97  ? 7.19180   -9.16875  35.54504  1.000 12.86808  ? 94  LYS H O    1 
ATOM   1430 C CB   . LYS A 1 97  ? 7.48230   -11.83114 36.76736  1.000 16.51441  ? 94  LYS H CB   1 
ATOM   1431 C CG   . LYS A 1 97  ? 6.85536   -11.48484 38.10891  1.000 15.28442  ? 94  LYS H CG   1 
ATOM   1432 C CD   . LYS A 1 97  ? 7.77958   -11.75363 39.26326  1.000 17.91618  ? 94  LYS H CD   1 
ATOM   1433 C CE   . LYS A 1 97  ? 7.05030   -11.57011 40.58481  1.000 17.21799  ? 94  LYS H CE   1 
ATOM   1434 N NZ   . LYS A 1 97  ? 6.42982   -10.21367 40.73968  1.000 16.89564  ? 94  LYS H NZ   1 
ATOM   1435 H H    . LYS A 1 97  ? 8.03789   -11.70247 34.29210  1.000 15.30133  ? 94  LYS H H    1 
ATOM   1436 H HA   . LYS A 1 97  ? 5.75844   -11.99475 35.71839  1.000 15.67149  ? 94  LYS H HA   1 
ATOM   1437 H HB2  . LYS A 1 97  ? 7.66290   -12.78409 36.75498  1.000 19.82412  ? 94  LYS H HB2  1 
ATOM   1438 H HB3  . LYS A 1 97  ? 8.31175   -11.33516 36.68418  1.000 19.82412  ? 94  LYS H HB3  1 
ATOM   1439 H HG2  . LYS A 1 97  ? 6.62828   -10.54185 38.11910  1.000 18.34814  ? 94  LYS H HG2  1 
ATOM   1440 H HG3  . LYS A 1 97  ? 6.05592   -12.01996 38.23317  1.000 18.34814  ? 94  LYS H HG3  1 
ATOM   1441 H HD2  . LYS A 1 97  ? 8.10426   -12.66634 39.21383  1.000 21.50625  ? 94  LYS H HD2  1 
ATOM   1442 H HD3  . LYS A 1 97  ? 8.52538   -11.13412 39.23344  1.000 21.50625  ? 94  LYS H HD3  1 
ATOM   1443 H HE2  . LYS A 1 97  ? 6.34163   -12.22958 40.64635  1.000 20.66842  ? 94  LYS H HE2  1 
ATOM   1444 H HE3  . LYS A 1 97  ? 7.68145   -11.69260 41.31114  1.000 20.66842  ? 94  LYS H HE3  1 
ATOM   1445 H HZ1  . LYS A 1 97  ? 6.03710   -10.14765 41.53562  1.000 20.28160  ? 94  LYS H HZ1  1 
ATOM   1446 H HZ2  . LYS A 1 97  ? 7.05483   -9.58360  40.67285  1.000 20.28160  ? 94  LYS H HZ2  1 
ATOM   1447 H HZ3  . LYS A 1 97  ? 5.81968   -10.08375 40.10489  1.000 20.28160  ? 94  LYS H HZ3  1 
ATOM   1448 N N    . LEU A 1 98  ? 4.98271   -9.63305  35.53126  1.000 13.31353  ? 95  LEU H N    1 
ATOM   1449 C CA   . LEU A 1 98  ? 4.59310   -8.27101  35.17129  1.000 14.10131  ? 95  LEU H CA   1 
ATOM   1450 C C    . LEU A 1 98  ? 4.85084   -7.27089  36.29186  1.000 17.16691  ? 95  LEU H C    1 
ATOM   1451 O O    . LEU A 1 98  ? 5.06535   -6.08151  36.02467  1.000 14.39250  ? 95  LEU H O    1 
ATOM   1452 C CB   . LEU A 1 98  ? 3.12016   -8.26144  34.75505  1.000 13.61124  ? 95  LEU H CB   1 
ATOM   1453 C CG   . LEU A 1 98  ? 2.91720   -9.00308  33.43308  1.000 12.09002  ? 95  LEU H CG   1 
ATOM   1454 C CD1  . LEU A 1 98  ? 1.44002   -9.29415  33.13917  1.000 16.60204  ? 95  LEU H CD1  1 
ATOM   1455 C CD2  . LEU A 1 98  ? 3.53855   -8.19679  32.30087  1.000 14.05941  ? 95  LEU H CD2  1 
ATOM   1456 H H    . LEU A 1 98  ? 4.32516   -10.15608 35.71476  1.000 15.98307  ? 95  LEU H H    1 
ATOM   1457 H HA   . LEU A 1 98  ? 5.12237   -7.97754  34.41324  1.000 16.92841  ? 95  LEU H HA   1 
ATOM   1458 H HB2  . LEU A 1 98  ? 2.59000   -8.69996  35.43881  1.000 16.34033  ? 95  LEU H HB2  1 
ATOM   1459 H HB3  . LEU A 1 98  ? 2.82382   -7.34469  34.64258  1.000 16.34033  ? 95  LEU H HB3  1 
ATOM   1460 H HG   . LEU A 1 98  ? 3.35497   -9.86627  33.49761  1.000 14.51486  ? 95  LEU H HG   1 
ATOM   1461 H HD11 . LEU A 1 98  ? 1.37379   -9.77344  32.29846  1.000 19.92928  ? 95  LEU H HD11 1 
ATOM   1462 H HD12 . LEU A 1 98  ? 1.07561   -9.83451  33.85758  1.000 19.92928  ? 95  LEU H HD12 1 
ATOM   1463 H HD13 . LEU A 1 98  ? 0.95836   -8.45428  33.07995  1.000 19.92928  ? 95  LEU H HD13 1 
ATOM   1464 H HD21 . LEU A 1 98  ? 3.17591   -8.50691  31.45634  1.000 16.87812  ? 95  LEU H HD21 1 
ATOM   1465 H HD22 . LEU A 1 98  ? 3.32614   -7.25885  32.42758  1.000 16.87812  ? 95  LEU H HD22 1 
ATOM   1466 H HD23 . LEU A 1 98  ? 4.50022   -8.32288  32.31416  1.000 16.87812  ? 95  LEU H HD23 1 
ATOM   1467 N N    . GLY A 1 99  ? 4.83996   -7.71868  37.53959  1.000 14.55422  ? 96  GLY H N    1 
ATOM   1468 C CA   . GLY A 1 99  ? 5.19177   -6.82463  38.62672  1.000 15.63530  ? 96  GLY H CA   1 
ATOM   1469 C C    . GLY A 1 99  ? 4.27036   -5.63275  38.75475  1.000 17.57907  ? 96  GLY H C    1 
ATOM   1470 O O    . GLY A 1 99  ? 4.74174   -4.50544  38.94437  1.000 14.64497  ? 96  GLY H O    1 
ATOM   1471 H H    . GLY A 1 99  ? 4.63650   -8.51978  37.77716  1.000 17.47190  ? 96  GLY H H    1 
ATOM   1472 H HA2  . GLY A 1 99  ? 5.16400   -7.31706  39.46197  1.000 18.76920  ? 96  GLY H HA2  1 
ATOM   1473 H HA3  . GLY A 1 99  ? 6.09263   -6.49419  38.48473  1.000 18.76920  ? 96  GLY H HA3  1 
ATOM   1474 N N    . THR A 1 100 ? 2.95801   -5.85168  38.65153  1.000 15.08985  ? 97  THR H N    1 
ATOM   1475 C CA   . THR A 1 100 ? 2.03099   -4.74845  38.84596  1.000 14.45290  ? 97  THR H CA   1 
ATOM   1476 C C    . THR A 1 100 ? 1.98389   -4.29015  40.29693  1.000 17.41024  ? 97  THR H C    1 
ATOM   1477 O O    . THR A 1 100 ? 1.61444   -3.14008  40.55565  1.000 16.51415  ? 97  THR H O    1 
ATOM   1478 C CB   . THR A 1 100 ? 0.61944   -5.13429  38.40340  1.000 14.92256  ? 97  THR H CB   1 
ATOM   1479 O OG1  . THR A 1 100 ? 0.21498   -6.32329  39.09015  1.000 15.89606  ? 97  THR H OG1  1 
ATOM   1480 C CG2  . THR A 1 100 ? 0.56972   -5.35643  36.90177  1.000 14.59114  ? 97  THR H CG2  1 
ATOM   1481 H H    . THR A 1 100 ? 2.59333   -6.61016  38.47457  1.000 18.11465  ? 97  THR H H    1 
ATOM   1482 H HA   . THR A 1 100 ? 2.32699   -4.01057  38.29026  1.000 17.35031  ? 97  THR H HA   1 
ATOM   1483 H HB   . THR A 1 100 ? 0.00124   -4.41770  38.61608  1.000 17.91390  ? 97  THR H HB   1 
ATOM   1484 H HG1  . THR A 1 100 ? 0.73651   -6.95464  38.90305  1.000 19.08211  ? 97  THR H HG1  1 
ATOM   1485 H HG21 . THR A 1 100 ? -0.32753  -5.60889  36.63327  1.000 17.51620  ? 97  THR H HG21 1 
ATOM   1486 H HG22 . THR A 1 100 ? 0.81991   -4.54232  36.43751  1.000 17.51620  ? 97  THR H HG22 1 
ATOM   1487 H HG23 . THR A 1 100 ? 1.18422   -6.06364  36.65050  1.000 17.51620  ? 97  THR H HG23 1 
ATOM   1488 N N    . GLY A 1 101 ? 2.34102   -5.15544  41.24161  1.000 15.94736  ? 98  GLY H N    1 
ATOM   1489 C CA   . GLY A 1 101 ? 2.16902   -4.83242  42.64456  1.000 20.97161  ? 98  GLY H CA   1 
ATOM   1490 C C    . GLY A 1 101 ? 3.36280   -5.14433  43.51616  1.000 18.15284  ? 98  GLY H C    1 
ATOM   1491 O O    . GLY A 1 101 ? 3.32582   -4.92056  44.72931  1.000 25.90880  ? 98  GLY H O    1 
ATOM   1492 H H    . GLY A 1 101 ? 2.68279   -5.93036  41.09231  1.000 19.14367  ? 98  GLY H H    1 
ATOM   1493 H HA2  . GLY A 1 101 ? 1.98360   -3.88374  42.72545  1.000 25.17276  ? 98  GLY H HA2  1 
ATOM   1494 H HA3  . GLY A 1 101 ? 1.41262   -5.33253  42.98902  1.000 25.17276  ? 98  GLY H HA3  1 
ATOM   1495 N N    . SER A 1 102 ? 4.42733   -5.66012  42.91813  1.000 20.06208  ? 99  SER H N    1 
ATOM   1496 C CA   . SER A 1 102 ? 5.59672   -6.10327  43.66276  1.000 18.98807  ? 99  SER H CA   1 
ATOM   1497 C C    . SER A 1 102 ? 6.85693   -5.58239  42.99167  1.000 17.83682  ? 99  SER H C    1 
ATOM   1498 O O    . SER A 1 102 ? 6.83815   -5.17378  41.82897  1.000 20.39461  ? 99  SER H O    1 
ATOM   1499 C CB   . SER A 1 102 ? 5.63519   -7.62545  43.76013  1.000 24.19162  ? 99  SER H CB   1 
ATOM   1500 O OG   . SER A 1 102 ? 5.53110   -8.19999  42.47538  1.000 22.65710  ? 99  SER H OG   1 
ATOM   1501 H H    . SER A 1 102 ? 4.49732   -5.76548  42.06748  1.000 24.08133  ? 99  SER H H    1 
ATOM   1502 H HA   . SER A 1 102 ? 5.57239   -5.73994  44.56182  1.000 22.79251  ? 99  SER H HA   1 
ATOM   1503 H HB2  . SER A 1 102 ? 6.47459   -7.89732  44.16312  1.000 29.03678  ? 99  SER H HB2  1 
ATOM   1504 H HB3  . SER A 1 102 ? 4.89209   -7.92823  44.30515  1.000 29.03678  ? 99  SER H HB3  1 
ATOM   1505 H HG   . SER A 1 102 ? 4.80080   -7.98265  42.12178  1.000 27.19535  ? 99  SER H HG   1 
ATOM   1506 N N    . ARG A 1 103 ? 7.96454   -5.60889  43.74729  1.000 17.80106  ? 100 ARG H N    1 
ATOM   1507 C CA   . ARG A 1 103 ? 9.21614   -5.02014  43.27705  1.000 21.07149  ? 100 ARG H CA   1 
ATOM   1508 C C    . ARG A 1 103 ? 9.78879   -5.74361  42.06781  1.000 19.30299  ? 100 ARG H C    1 
ATOM   1509 O O    . ARG A 1 103 ? 10.46218  -5.11854  41.24136  1.000 19.02279  ? 100 ARG H O    1 
ATOM   1510 C CB   . ARG A 1 103 ? 10.27540  -5.04148  44.38247  1.000 30.34057  ? 100 ARG H CB   1 
ATOM   1511 C CG   . ARG A 1 103 ? 10.09342  -4.02790  45.48525  1.000 42.72682  ? 100 ARG H CG   1 
ATOM   1512 C CD   . ARG A 1 103 ? 11.17404  -4.20478  46.54491  1.000 51.07245  ? 100 ARG H CD   1 
ATOM   1513 N NE   . ARG A 1 103 ? 11.16882  -5.55655  47.09505  1.000 60.37080  ? 100 ARG H NE   1 
ATOM   1514 C CZ   . ARG A 1 103 ? 12.01076  -5.99894  48.01956  1.000 65.75259  ? 100 ARG H CZ   1 
ATOM   1515 N NH1  . ARG A 1 103 ? 12.95267  -5.21989  48.52667  1.000 57.45769  ? 100 ARG H NH1  1 
ATOM   1516 N NH2  . ARG A 1 103 ? 11.90217  -7.25404  48.44853  1.000 66.84429  ? 100 ARG H NH2  1 
ATOM   1517 H H    . ARG A 1 103 ? 8.01358   -5.96045  44.53062  1.000 21.36811  ? 100 ARG H H    1 
ATOM   1518 H HA   . ARG A 1 103 ? 9.01739   -4.10243  43.03372  1.000 25.29262  ? 100 ARG H HA   1 
ATOM   1519 H HB2  . ARG A 1 103 ? 10.26686  -5.91948  44.79471  1.000 36.41552  ? 100 ARG H HB2  1 
ATOM   1520 H HB3  . ARG A 1 103 ? 11.14069  -4.87350  43.97754  1.000 36.41552  ? 100 ARG H HB3  1 
ATOM   1521 H HG2  . ARG A 1 103 ? 10.16093  -3.13203  45.11952  1.000 51.27902  ? 100 ARG H HG2  1 
ATOM   1522 H HG3  . ARG A 1 103 ? 9.22643   -4.15151  45.90232  1.000 51.27902  ? 100 ARG H HG3  1 
ATOM   1523 H HD2  . ARG A 1 103 ? 12.04343  -4.04080  46.14722  1.000 61.29378  ? 100 ARG H HD2  1 
ATOM   1524 H HD3  . ARG A 1 103 ? 11.01775  -3.57984  47.27012  1.000 61.29378  ? 100 ARG H HD3  1 
ATOM   1525 H HE   . ARG A 1 103 ? 10.57726  -6.10581  46.79845  1.000 72.45179  ? 100 ARG H HE   1 
ATOM   1526 H HH11 . ARG A 1 103 ? 13.02913  -4.40669  48.25750  1.000 68.95606  ? 100 ARG H HH11 1 
ATOM   1527 H HH12 . ARG A 1 103 ? 13.48832  -5.52682  49.12540  1.000 68.95606  ? 100 ARG H HH12 1 
ATOM   1528 H HH21 . ARG A 1 103 ? 11.29172  -7.76719  48.12662  1.000 80.21998  ? 100 ARG H HH21 1 
ATOM   1529 H HH22 . ARG A 1 103 ? 12.44244  -7.55196  49.04766  1.000 80.21998  ? 100 ARG H HH22 1 
ATOM   1530 N N    . PHE A 1 104 A 9.57440   -7.05246  41.96857  1.000 19.71620  ? 100 PHE H N    1 
ATOM   1531 C CA   . PHE A 1 104 A 10.25220  -7.88345  40.97992  1.000 15.90887  ? 100 PHE H CA   1 
ATOM   1532 C C    . PHE A 1 104 A 9.42966   -7.93040  39.70087  1.000 17.73695  ? 100 PHE H C    1 
ATOM   1533 O O    . PHE A 1 104 A 8.28032   -8.38743  39.70826  1.000 16.75813  ? 100 PHE H O    1 
ATOM   1534 C CB   . PHE A 1 104 A 10.46982  -9.29526  41.52632  1.000 19.57787  ? 100 PHE H CB   1 
ATOM   1535 C CG   . PHE A 1 104 A 11.29437  -10.19652 40.62428  1.000 15.75517  ? 100 PHE H CG   1 
ATOM   1536 C CD1  . PHE A 1 104 A 12.29349  -9.68309  39.81811  1.000 19.21689  ? 100 PHE H CD1  1 
ATOM   1537 C CD2  . PHE A 1 104 A 11.06599  -11.56276 40.60086  1.000 22.27115  ? 100 PHE H CD2  1 
ATOM   1538 C CE1  . PHE A 1 104 A 13.04531  -10.50517 39.00782  1.000 19.83847  ? 100 PHE H CE1  1 
ATOM   1539 C CE2  . PHE A 1 104 A 11.81352  -12.39309 39.78669  1.000 21.01280  ? 100 PHE H CE2  1 
ATOM   1540 C CZ   . PHE A 1 104 A 12.80984  -11.86303 38.99394  1.000 19.16179  ? 100 PHE H CZ   1 
ATOM   1541 H H    . PHE A 1 104 A 9.03109   -7.48963  42.47186  1.000 23.66627  ? 100 PHE H H    1 
ATOM   1542 H HA   . PHE A 1 104 A 11.11581  -7.49325  40.77297  1.000 19.09747  ? 100 PHE H HA   1 
ATOM   1543 H HB2  . PHE A 1 104 A 10.93140  -9.23009  42.37697  1.000 23.50028  ? 100 PHE H HB2  1 
ATOM   1544 H HB3  . PHE A 1 104 A 9.60462   -9.71607  41.64972  1.000 23.50028  ? 100 PHE H HB3  1 
ATOM   1545 H HD1  . PHE A 1 104 A 12.46060  -8.76824  39.82299  1.000 23.06710  ? 100 PHE H HD1  1 
ATOM   1546 H HD2  . PHE A 1 104 A 10.40100  -11.92612 41.13998  1.000 26.73222  ? 100 PHE H HD2  1 
ATOM   1547 H HE1  . PHE A 1 104 A 13.71221  -10.14366 38.46980  1.000 23.81300  ? 100 PHE H HE1  1 
ATOM   1548 H HE2  . PHE A 1 104 A 11.64484  -13.30757 39.77357  1.000 25.22219  ? 100 PHE H HE2  1 
ATOM   1549 H HZ   . PHE A 1 104 A 13.32091  -12.41982 38.45200  1.000 23.00098  ? 100 PHE H HZ   1 
ATOM   1550 N N    . ALA A 1 105 ? 10.01289  -7.43996  38.61288  1.000 17.48741  ? 101 ALA H N    1 
ATOM   1551 C CA   . ALA A 1 105 ? 9.43830   -7.56833  37.28262  1.000 20.21245  ? 101 ALA H CA   1 
ATOM   1552 C C    . ALA A 1 105 ? 10.55507  -7.97325  36.33839  1.000 18.15600  ? 101 ALA H C    1 
ATOM   1553 O O    . ALA A 1 105 ? 11.68617  -7.50107  36.47218  1.000 16.83304  ? 101 ALA H O    1 
ATOM   1554 C CB   . ALA A 1 105 ? 8.78371   -6.26662  36.81387  1.000 19.48059  ? 101 ALA H CB   1 
ATOM   1555 H H    . ALA A 1 105 ? 10.76202  -7.01767  38.62132  1.000 20.99172  ? 101 ALA H H    1 
ATOM   1556 H HA   . ALA A 1 105 ? 8.74842   -8.25015  37.27347  1.000 24.26177  ? 101 ALA H HA   1 
ATOM   1557 H HB1  . ALA A 1 105 ? 8.39050   -6.40824  35.93852  1.000 23.38354  ? 101 ALA H HB1  1 
ATOM   1558 H HB2  . ALA A 1 105 ? 8.09544   -6.01286  37.44852  1.000 23.38354  ? 101 ALA H HB2  1 
ATOM   1559 H HB3  . ALA A 1 105 ? 9.46000   -5.57301  36.76441  1.000 23.38354  ? 101 ALA H HB3  1 
ATOM   1560 N N    . ILE A 1 106 ? 10.24655  -8.86829  35.40545  1.000 15.31072  ? 102 ILE H N    1 
ATOM   1561 C CA   . ILE A 1 106 ? 11.24842  -9.34720  34.46523  1.000 15.17115  ? 102 ILE H CA   1 
ATOM   1562 C C    . ILE A 1 106 ? 10.53413  -9.92740  33.25487  1.000 14.85336  ? 102 ILE H C    1 
ATOM   1563 O O    . ILE A 1 106 ? 9.51323   -10.60500 33.38545  1.000 12.63099  ? 102 ILE H O    1 
ATOM   1564 C CB   . ILE A 1 106 ? 12.18224  -10.38326 35.12780  1.000 17.94825  ? 102 ILE H CB   1 
ATOM   1565 C CG1  . ILE A 1 106 ? 13.39468  -10.63457 34.23652  1.000 20.80945  ? 102 ILE H CG1  1 
ATOM   1566 C CG2  . ILE A 1 106 ? 11.42994  -11.68097 35.40804  1.000 17.79480  ? 102 ILE H CG2  1 
ATOM   1567 C CD1  . ILE A 1 106 ? 14.42653  -11.53221 34.87965  1.000 28.91014  ? 102 ILE H CD1  1 
ATOM   1568 H H    . ILE A 1 106 ? 9.46530   -9.21147  35.29831  1.000 18.37969  ? 102 ILE H H    1 
ATOM   1569 H HA   . ILE A 1 106 ? 11.78445  -8.59621  34.16593  1.000 18.21222  ? 102 ILE H HA   1 
ATOM   1570 H HB   . ILE A 1 106 ? 12.49157  -10.02818 35.97581  1.000 21.54473  ? 102 ILE H HB   1 
ATOM   1571 H HG12 . ILE A 1 106 ? 13.09921  -11.05886 33.41580  1.000 24.97818  ? 102 ILE H HG12 1 
ATOM   1572 H HG13 . ILE A 1 106 ? 13.81962  -9.78578  34.03683  1.000 24.97818  ? 102 ILE H HG13 1 
ATOM   1573 H HG21 . ILE A 1 106 ? 11.96107  -12.23140 36.00456  1.000 21.36059  ? 102 ILE H HG21 1 
ATOM   1574 H HG22 . ILE A 1 106 ? 10.57906  -11.46944 35.82296  1.000 21.36059  ? 102 ILE H HG22 1 
ATOM   1575 H HG23 . ILE A 1 106 ? 11.28262  -12.14776 34.57060  1.000 21.36059  ? 102 ILE H HG23 1 
ATOM   1576 H HD11 . ILE A 1 106 ? 15.27845  -11.40399 34.43389  1.000 34.69900  ? 102 ILE H HD11 1 
ATOM   1577 H HD12 . ILE A 1 106 ? 14.50603  -11.30014 35.81812  1.000 34.69900  ? 102 ILE H HD12 1 
ATOM   1578 H HD13 . ILE A 1 106 ? 14.14196  -12.45520 34.79010  1.000 34.69900  ? 102 ILE H HD13 1 
ATOM   1579 N N    . TRP A 1 107 ? 11.10209  -9.66866  32.07814  1.000 14.71156  ? 103 TRP H N    1 
ATOM   1580 C CA   . TRP A 1 107 ? 10.55052  -10.06983 30.79562  1.000 13.73243  ? 103 TRP H CA   1 
ATOM   1581 C C    . TRP A 1 107 ? 11.60335  -10.81212 29.98968  1.000 14.16550  ? 103 TRP H C    1 
ATOM   1582 O O    . TRP A 1 107 ? 12.77678  -10.42879 29.99099  1.000 14.74383  ? 103 TRP H O    1 
ATOM   1583 C CB   . TRP A 1 107 ? 10.11537  -8.86894  29.95677  1.000 17.71175  ? 103 TRP H CB   1 
ATOM   1584 C CG   . TRP A 1 107 ? 8.91783   -8.15254  30.41558  1.000 14.77082  ? 103 TRP H CG   1 
ATOM   1585 C CD1  . TRP A 1 107 ? 8.73774   -7.52927  31.61599  1.000 16.31229  ? 103 TRP H CD1  1 
ATOM   1586 C CD2  . TRP A 1 107 ? 7.72173   -7.94376  29.66577  1.000 16.41302  ? 103 TRP H CD2  1 
ATOM   1587 N NE1  . TRP A 1 107 ? 7.49203   -6.95268  31.66058  1.000 16.96939  ? 103 TRP H NE1  1 
ATOM   1588 C CE2  . TRP A 1 107 ? 6.84726   -7.19904  30.47569  1.000 15.42817  ? 103 TRP H CE2  1 
ATOM   1589 C CE3  . TRP A 1 107 ? 7.30002   -8.32563  28.38510  1.000 16.77404  ? 103 TRP H CE3  1 
ATOM   1590 C CZ2  . TRP A 1 107 ? 5.58204   -6.82104  30.04991  1.000 15.98575  ? 103 TRP H CZ2  1 
ATOM   1591 C CZ3  . TRP A 1 107 ? 6.03475   -7.95166  27.96616  1.000 16.70672  ? 103 TRP H CZ3  1 
ATOM   1592 C CH2  . TRP A 1 107 ? 5.19580   -7.20351  28.79458  1.000 16.53630  ? 103 TRP H CH2  1 
ATOM   1593 H H    . TRP A 1 107 ? 11.84377  -9.24078  31.99792  1.000 17.66070  ? 103 TRP H H    1 
ATOM   1594 H HA   . TRP A 1 107 ? 9.78904   -10.64549 30.96785  1.000 16.48575  ? 103 TRP H HA   1 
ATOM   1595 H HB2  . TRP A 1 107 ? 10.84377  -8.22846  29.94601  1.000 21.26093  ? 103 TRP H HB2  1 
ATOM   1596 H HB3  . TRP A 1 107 ? 9.93366   -9.17986  29.05610  1.000 21.26093  ? 103 TRP H HB3  1 
ATOM   1597 H HD1  . TRP A 1 107 ? 9.36513   -7.49936  32.30184  1.000 19.58158  ? 103 TRP H HD1  1 
ATOM   1598 H HE1  . TRP A 1 107 ? 7.16918   -6.50961  32.32320  1.000 20.37010  ? 103 TRP H HE1  1 
ATOM   1599 H HE3  . TRP A 1 107 ? 7.85806   -8.81955  27.82875  1.000 20.13569  ? 103 TRP H HE3  1 
ATOM   1600 H HZ2  . TRP A 1 107 ? 5.01712   -6.32567  30.59797  1.000 19.18974  ? 103 TRP H HZ2  1 
ATOM   1601 H HZ3  . TRP A 1 107 ? 5.73919   -8.20231  27.12075  1.000 20.05490  ? 103 TRP H HZ3  1 
ATOM   1602 H HH2  . TRP A 1 107 ? 4.35349   -6.95918  28.48519  1.000 19.85039  ? 103 TRP H HH2  1 
ATOM   1603 N N    . GLY A 1 108 ? 11.17580  -11.84342 29.27207  1.000 14.89865  ? 104 GLY H N    1 
ATOM   1604 C CA   . GLY A 1 108 ? 11.98590  -12.38077 28.19996  1.000 18.10675  ? 104 GLY H CA   1 
ATOM   1605 C C    . GLY A 1 108 ? 12.11227  -11.37036 27.07275  1.000 16.79709  ? 104 GLY H C    1 
ATOM   1606 O O    . GLY A 1 108 ? 11.42897  -10.34856 27.03706  1.000 17.58550  ? 104 GLY H O    1 
ATOM   1607 H H    . GLY A 1 108 ? 10.42413  -12.24469 29.38853  1.000 17.88522  ? 104 GLY H H    1 
ATOM   1608 H HA2  . GLY A 1 108 ? 12.87217  -12.59276 28.53234  1.000 21.73493  ? 104 GLY H HA2  1 
ATOM   1609 H HA3  . GLY A 1 108 ? 11.57718  -13.18901 27.85269  1.000 21.73493  ? 104 GLY H HA3  1 
ATOM   1610 N N    . GLN A 1 109 ? 13.01576  -11.64867 26.13177  1.000 13.62992  ? 105 GLN H N    1 
ATOM   1611 C CA   . GLN A 1 109 ? 13.27738  -10.68361 25.07102  1.000 14.69554  ? 105 GLN H CA   1 
ATOM   1612 C C    . GLN A 1 109 ? 12.18642  -10.66539 24.00355  1.000 15.82248  ? 105 GLN H C    1 
ATOM   1613 O O    . GLN A 1 109 ? 12.14297  -9.72489  23.19799  1.000 15.10570  ? 105 GLN H O    1 
ATOM   1614 C CB   . GLN A 1 109 ? 14.63922  -10.96689 24.41729  1.000 21.02868  ? 105 GLN H CB   1 
ATOM   1615 C CG   . GLN A 1 109 ? 14.70382  -12.22394 23.53574  1.000 27.80335  ? 105 GLN H CG   1 
ATOM   1616 C CD   . GLN A 1 109 ? 14.95871  -13.51206 24.31219  1.000 33.07403  ? 105 GLN H CD   1 
ATOM   1617 O OE1  . GLN A 1 109 ? 14.88532  -13.54998 25.54687  1.000 24.82973  ? 105 GLN H OE1  1 
ATOM   1618 N NE2  . GLN A 1 109 ? 15.26906  -14.57892 23.58172  1.000 29.77479  ? 105 GLN H NE2  1 
ATOM   1619 H H    . GLN A 1 109 ? 13.47782  -12.37274 26.08906  1.000 16.36273  ? 105 GLN H H    1 
ATOM   1620 H HA   . GLN A 1 109 ? 13.32063  -9.79774  25.46380  1.000 17.64148  ? 105 GLN H HA   1 
ATOM   1621 H HB2  . GLN A 1 109 ? 14.87166  -10.20979 23.85722  1.000 25.24125  ? 105 GLN H HB2  1 
ATOM   1622 H HB3  . GLN A 1 109 ? 15.29844  -11.07395 25.12075  1.000 25.24125  ? 105 GLN H HB3  1 
ATOM   1623 H HG2  . GLN A 1 109 ? 13.85817  -12.32225 23.07087  1.000 33.37085  ? 105 GLN H HG2  1 
ATOM   1624 H HG3  . GLN A 1 109 ? 15.42435  -12.11839 22.89495  1.000 33.37085  ? 105 GLN H HG3  1 
ATOM   1625 H HE21 . GLN A 1 109 ? 15.31551  -14.51500 22.72536  1.000 35.73659  ? 105 GLN H HE21 1 
ATOM   1626 H HE22 . GLN A 1 109 ? 15.42334  -15.33284 23.96565  1.000 35.73659  ? 105 GLN H HE22 1 
ATOM   1627 N N    . GLY A 1 110 ? 11.31701  -11.66311 23.98301  1.000 16.84826  ? 106 GLY H N    1 
ATOM   1628 C CA   . GLY A 1 110 ? 10.27376  -11.78589 22.96437  1.000 17.87052  ? 106 GLY H CA   1 
ATOM   1629 C C    . GLY A 1 110 ? 10.77022  -12.54718 21.75366  1.000 18.26855  ? 106 GLY H C    1 
ATOM   1630 O O    . GLY A 1 110 ? 11.91690  -12.47161 21.36435  1.000 16.35384  ? 106 GLY H O    1 
ATOM   1631 H H    . GLY A 1 110 ? 11.30459  -12.30100 24.55967  1.000 20.22474  ? 106 GLY H H    1 
ATOM   1632 H HA2  . GLY A 1 110 ? 9.51135   -12.25703 23.33538  1.000 21.45146  ? 106 GLY H HA2  1 
ATOM   1633 H HA3  . GLY A 1 110 ? 9.99142   -10.90239 22.68044  1.000 21.45146  ? 106 GLY H HA3  1 
ATOM   1634 N N    . THR A 1 111 ? 9.85692   -13.31883 21.13275  1.000 15.64014  ? 107 THR H N    1 
ATOM   1635 C CA   . THR A 1 111 ? 10.21008  -14.01228 19.89421  1.000 18.20622  ? 107 THR H CA   1 
ATOM   1636 C C    . THR A 1 111 ? 9.01643   -13.99847 18.95357  1.000 16.38586  ? 107 THR H C    1 
ATOM   1637 O O    . THR A 1 111 ? 7.87547   -14.15506 19.39302  1.000 17.32550  ? 107 THR H O    1 
ATOM   1638 C CB   . THR A 1 111 ? 10.65955  -15.45696 20.15939  1.000 24.96761  ? 107 THR H CB   1 
ATOM   1639 O OG1  . THR A 1 111 ? 11.12936  -16.03967 18.93890  1.000 39.86913  ? 107 THR H OG1  1 
ATOM   1640 C CG2  . THR A 1 111 ? 9.51751   -16.28870 20.68594  1.000 25.42751  ? 107 THR H CG2  1 
ATOM   1641 H H    . THR A 1 111 ? 9.05216   -13.44761 21.40731  1.000 18.77500  ? 107 THR H H    1 
ATOM   1642 H HA   . THR A 1 111 ? 10.94313  -13.54758 19.46111  1.000 21.85429  ? 107 THR H HA   1 
ATOM   1643 H HB   . THR A 1 111 ? 11.36769  -15.45350 20.82228  1.000 29.96797  ? 107 THR H HB   1 
ATOM   1644 H HG1  . THR A 1 111 ? 11.75687  -15.57889 18.62344  1.000 47.84979  ? 107 THR H HG1  1 
ATOM   1645 H HG21 . THR A 1 111 ? 9.85640   -17.11290 21.06901  1.000 30.51985  ? 107 THR H HG21 1 
ATOM   1646 H HG22 . THR A 1 111 ? 9.03739   -15.79734 21.37074  1.000 30.51985  ? 107 THR H HG22 1 
ATOM   1647 H HG23 . THR A 1 111 ? 8.90487   -16.50490 19.96564  1.000 30.51985  ? 107 THR H HG23 1 
ATOM   1648 N N    . LEU A 1 112 ? 9.28706   -13.79868 17.66317  1.000 14.69057  ? 108 LEU H N    1 
ATOM   1649 C CA   . LEU A 1 112 ? 8.23159   -13.71946 16.66185  1.000 16.04648  ? 108 LEU H CA   1 
ATOM   1650 C C    . LEU A 1 112 ? 7.81355   -15.11398 16.20964  1.000 18.22147  ? 108 LEU H C    1 
ATOM   1651 O O    . LEU A 1 112 ? 8.65020   -15.92755 15.80720  1.000 18.50806  ? 108 LEU H O    1 
ATOM   1652 C CB   . LEU A 1 112 ? 8.69938   -12.90283 15.45568  1.000 17.59125  ? 108 LEU H CB   1 
ATOM   1653 C CG   . LEU A 1 112 ? 7.69947   -12.75443 14.30063  1.000 18.61188  ? 108 LEU H CG   1 
ATOM   1654 C CD1  . LEU A 1 112 ? 6.44983   -12.00712 14.72535  1.000 18.82094  ? 108 LEU H CD1  1 
ATOM   1655 C CD2  . LEU A 1 112 ? 8.35639   -12.06114 13.13538  1.000 19.19763  ? 108 LEU H CD2  1 
ATOM   1656 H H    . LEU A 1 112 ? 10.07978  -13.70563 17.34296  1.000 17.63552  ? 108 LEU H H    1 
ATOM   1657 H HA   . LEU A 1 112 ? 7.46029   -13.28182 17.05489  1.000 19.26261  ? 108 LEU H HA   1 
ATOM   1658 H HB2  . LEU A 1 112 ? 8.91440   -12.00842 15.76341  1.000 21.11634  ? 108 LEU H HB2  1 
ATOM   1659 H HB3  . LEU A 1 112 ? 9.49216   -13.32865 15.09364  1.000 21.11634  ? 108 LEU H HB3  1 
ATOM   1660 H HG   . LEU A 1 112 ? 7.41939   -13.64098 14.02405  1.000 22.34109  ? 108 LEU H HG   1 
ATOM   1661 H HD11 . LEU A 1 112 ? 5.86940   -11.89935 13.95569  1.000 22.59197  ? 108 LEU H HD11 1 
ATOM   1662 H HD12 . LEU A 1 112 ? 5.99521   -12.51754 15.41361  1.000 22.59197  ? 108 LEU H HD12 1 
ATOM   1663 H HD13 . LEU A 1 112 ? 6.70432   -11.13767 15.07205  1.000 22.59197  ? 108 LEU H HD13 1 
ATOM   1664 H HD21 . LEU A 1 112 ? 7.71067   -11.96990 12.41731  1.000 23.04399  ? 108 LEU H HD21 1 
ATOM   1665 H HD22 . LEU A 1 112 ? 8.66075   -11.18515 13.41983  1.000 23.04399  ? 108 LEU H HD22 1 
ATOM   1666 H HD23 . LEU A 1 112 ? 9.11083   -12.59242 12.83628  1.000 23.04399  ? 108 LEU H HD23 1 
ATOM   1667 N N    . VAL A 1 113 ? 6.51781   -15.38863 16.27496  1.000 18.27875  ? 109 VAL H N    1 
ATOM   1668 C CA   . VAL A 1 113 ? 5.93521   -16.59172 15.69580  1.000 16.60345  ? 109 VAL H CA   1 
ATOM   1669 C C    . VAL A 1 113 ? 5.05239   -16.13149 14.54557  1.000 16.24099  ? 109 VAL H C    1 
ATOM   1670 O O    . VAL A 1 113 ? 4.13000   -15.32699 14.74206  1.000 15.79493  ? 109 VAL H O    1 
ATOM   1671 C CB   . VAL A 1 113 ? 5.14770   -17.40996 16.73235  1.000 16.13580  ? 109 VAL H CB   1 
ATOM   1672 C CG1  . VAL A 1 113 ? 4.51391   -18.64178 16.08283  1.000 17.89334  ? 109 VAL H CG1  1 
ATOM   1673 C CG2  . VAL A 1 113 ? 6.06232   -17.83874 17.86180  1.000 19.15501  ? 109 VAL H CG2  1 
ATOM   1674 H H    . VAL A 1 113 ? 5.94097   -14.87988 16.65972  1.000 21.94134  ? 109 VAL H H    1 
ATOM   1675 H HA   . VAL A 1 113 ? 6.63209   -17.16992 15.34802  1.000 19.93098  ? 109 VAL H HA   1 
ATOM   1676 H HB   . VAL A 1 113 ? 4.43861   -16.85450 17.09229  1.000 19.36979  ? 109 VAL H HB   1 
ATOM   1677 H HG11 . VAL A 1 113 ? 4.15478   -19.21558 16.77758  1.000 21.47884  ? 109 VAL H HG11 1 
ATOM   1678 H HG12 . VAL A 1 113 ? 3.80189   -18.35499 15.48981  1.000 21.47884  ? 109 VAL H HG12 1 
ATOM   1679 H HG13 . VAL A 1 113 ? 5.19261   -19.11752 15.57891  1.000 21.47884  ? 109 VAL H HG13 1 
ATOM   1680 H HG21 . VAL A 1 113 ? 5.54404   -18.32891 18.51908  1.000 22.99285  ? 109 VAL H HG21 1 
ATOM   1681 H HG22 . VAL A 1 113 ? 6.76272   -18.40584 17.50301  1.000 22.99285  ? 109 VAL H HG22 1 
ATOM   1682 H HG23 . VAL A 1 113 ? 6.45204   -17.04956 18.26948  1.000 22.99285  ? 109 VAL H HG23 1 
ATOM   1683 N N    . THR A 1 114 ? 5.37166   -16.60593 13.34291  1.000 17.03136  ? 110 THR H N    1 
ATOM   1684 C CA   . THR A 1 114 ? 4.62176   -16.29404 12.13371  1.000 15.91843  ? 110 THR H CA   1 
ATOM   1685 C C    . THR A 1 114 ? 3.83364   -17.52696 11.72161  1.000 15.81652  ? 110 THR H C    1 
ATOM   1686 O O    . THR A 1 114 ? 4.40760   -18.60758 11.57696  1.000 19.73924  ? 110 THR H O    1 
ATOM   1687 C CB   . THR A 1 114 ? 5.55577   -15.86733 10.99759  1.000 19.27447  ? 110 THR H CB   1 
ATOM   1688 O OG1  . THR A 1 114 ? 6.40673   -14.80033 11.43979  1.000 19.17733  ? 110 THR H OG1  1 
ATOM   1689 C CG2  . THR A 1 114 ? 4.74712   -15.40155 9.79950   1.000 19.91842  ? 110 THR H CG2  1 
ATOM   1690 H H    . THR A 1 114 ? 6.04072   -17.12715 13.20046  1.000 20.44447  ? 110 THR H H    1 
ATOM   1691 H HA   . THR A 1 114 ? 4.00634   -15.56468 12.30744  1.000 19.10895  ? 110 THR H HA   1 
ATOM   1692 H HB   . THR A 1 114 ? 6.10366   -16.62141 10.72913  1.000 23.13620  ? 110 THR H HB   1 
ATOM   1693 H HG1  . THR A 1 114 ? 6.93648   -14.58198 10.82556  1.000 23.01963  ? 110 THR H HG1  1 
ATOM   1694 H HG21 . THR A 1 114 ? 5.33530   -15.01371 9.13278   1.000 23.90894  ? 110 THR H HG21 1 
ATOM   1695 H HG22 . THR A 1 114 ? 4.27595   -16.15216 9.40519   1.000 23.90894  ? 110 THR H HG22 1 
ATOM   1696 H HG23 . THR A 1 114 ? 4.10016   -14.73354 10.07535  1.000 23.90894  ? 110 THR H HG23 1 
ATOM   1697 N N    . VAL A 1 115 ? 2.53190   -17.36880 11.53042  1.000 17.92992  ? 111 VAL H N    1 
ATOM   1698 C CA   . VAL A 1 115 ? 1.66304   -18.46637 11.11587  1.000 18.54475  ? 111 VAL H CA   1 
ATOM   1699 C C    . VAL A 1 115 ? 1.28122   -18.21046 9.66532   1.000 18.39992  ? 111 VAL H C    1 
ATOM   1700 O O    . VAL A 1 115 ? 0.56223   -17.24821 9.35945   1.000 18.66111  ? 111 VAL H O    1 
ATOM   1701 C CB   . VAL A 1 115 ? 0.42492   -18.59072 12.01279  1.000 16.46872  ? 111 VAL H CB   1 
ATOM   1702 C CG1  . VAL A 1 115 ? -0.37196  -19.84980 11.65099  1.000 17.23116  ? 111 VAL H CG1  1 
ATOM   1703 C CG2  . VAL A 1 115 ? 0.83070   -18.61346 13.47654  1.000 15.34536  ? 111 VAL H CG2  1 
ATOM   1704 H H    . VAL A 1 115 ? 2.11918   -16.62173 11.63602  1.000 21.52274  ? 111 VAL H H    1 
ATOM   1705 H HA   . VAL A 1 115 ? 2.15090   -19.30340 11.16359  1.000 22.26054  ? 111 VAL H HA   1 
ATOM   1706 H HB   . VAL A 1 115 ? -0.14707  -17.82025 11.87097  1.000 19.76930  ? 111 VAL H HB   1 
ATOM   1707 H HG11 . VAL A 1 115 ? -1.09732  -19.95776 12.28589  1.000 20.68422  ? 111 VAL H HG11 1 
ATOM   1708 H HG12 . VAL A 1 115 ? -0.72901  -19.75082 10.75454  1.000 20.68422  ? 111 VAL H HG12 1 
ATOM   1709 H HG13 . VAL A 1 115 ? 0.21809   -20.61876 11.68899  1.000 20.68422  ? 111 VAL H HG13 1 
ATOM   1710 H HG21 . VAL A 1 115 ? 0.04596   -18.78867 14.01911  1.000 18.42127  ? 111 VAL H HG21 1 
ATOM   1711 H HG22 . VAL A 1 115 ? 1.48877   -19.31329 13.61098  1.000 18.42127  ? 111 VAL H HG22 1 
ATOM   1712 H HG23 . VAL A 1 115 ? 1.21043   -17.75260 13.71238  1.000 18.42127  ? 111 VAL H HG23 1 
ATOM   1713 N N    . SER A 1 116 ? 1.76659   -19.06946 8.76950   1.000 20.74505  ? 112 SER H N    1 
ATOM   1714 C CA   . SER A 1 116 ? 1.57369   -18.87498 7.34019   1.000 22.90787  ? 112 SER H CA   1 
ATOM   1715 C C    . SER A 1 116 ? 1.84622   -20.18275 6.61165   1.000 22.23326  ? 112 SER H C    1 
ATOM   1716 O O    . SER A 1 116 ? 2.67204   -20.98842 7.04397   1.000 23.02755  ? 112 SER H O    1 
ATOM   1717 C CB   . SER A 1 116 ? 2.48848   -17.76681 6.80455   1.000 27.45709  ? 112 SER H CB   1 
ATOM   1718 O OG   . SER A 1 116 ? 2.39231   -17.66351 5.39469   1.000 32.24018  ? 112 SER H OG   1 
ATOM   1719 H H    . SER A 1 116 ? 2.21373   -19.77652 8.96882   1.000 24.90090  ? 112 SER H H    1 
ATOM   1720 H HA   . SER A 1 116 ? 0.65111   -18.62699 7.17210   1.000 27.49628  ? 112 SER H HA   1 
ATOM   1721 H HB2  . SER A 1 116 ? 2.22452   -16.92172 7.20084   1.000 32.95534  ? 112 SER H HB2  1 
ATOM   1722 H HB3  . SER A 1 116 ? 3.40576   -17.97303 7.04324   1.000 32.95534  ? 112 SER H HB3  1 
ATOM   1723 H HG   . SER A 1 116 ? 2.89493   -17.05062 5.11658   1.000 38.69505  ? 112 SER H HG   1 
ATOM   1724 N N    . SER A 1 117 ? 1.12340   -20.38959 5.50768   1.000 29.15639  ? 113 SER H N    1 
ATOM   1725 C CA   . SER A 1 117 ? 1.31126   -21.56860 4.67007   1.000 34.20662  ? 113 SER H CA   1 
ATOM   1726 C C    . SER A 1 117 ? 2.52161   -21.45824 3.75156   1.000 30.61766  ? 113 SER H C    1 
ATOM   1727 O O    . SER A 1 117 ? 2.86638   -22.44228 3.08731   1.000 39.26690  ? 113 SER H O    1 
ATOM   1728 C CB   . SER A 1 117 ? 0.05868   -21.82088 3.81971   1.000 32.44953  ? 113 SER H CB   1 
ATOM   1729 O OG   . SER A 1 117 ? -1.02689  -22.24918 4.62235   1.000 46.83817  ? 113 SER H OG   1 
ATOM   1730 H H    . SER A 1 117 ? 0.51307   -19.85502 5.22247   1.000 34.99451  ? 113 SER H H    1 
ATOM   1731 H HA   . SER A 1 117 ? 1.44141   -22.33533 5.24980   1.000 41.05478  ? 113 SER H HA   1 
ATOM   1732 H HB2  . SER A 1 117 ? -0.18790  -20.99701 3.37099   1.000 38.94627  ? 113 SER H HB2  1 
ATOM   1733 H HB3  . SER A 1 117 ? 0.25636   -22.50885 3.16510   1.000 38.94627  ? 113 SER H HB3  1 
ATOM   1734 H HG   . SER A 1 117 ? -1.19528  -21.67241 5.20936   1.000 56.21263  ? 113 SER H HG   1 
ATOM   1735 N N    . ALA A 1 118 ? 3.17845   -20.30600 3.70669   1.000 31.23482  ? 114 ALA H N    1 
ATOM   1736 C CA   . ALA A 1 118 ? 4.28648   -20.10211 2.78777   1.000 26.99237  ? 114 ALA H CA   1 
ATOM   1737 C C    . ALA A 1 118 ? 5.54086   -20.82977 3.26849   1.000 29.88889  ? 114 ALA H C    1 
ATOM   1738 O O    . ALA A 1 118 ? 5.64212   -21.26263 4.41884   1.000 36.92275  ? 114 ALA H O    1 
ATOM   1739 C CB   . ALA A 1 118 ? 4.56478   -18.60825 2.62421   1.000 33.01415  ? 114 ALA H CB   1 
ATOM   1740 H H    . ALA A 1 118 ? 3.00050   -19.62467 4.20036   1.000 37.48862  ? 114 ALA H H    1 
ATOM   1741 H HA   . ALA A 1 118 ? 4.05628   -20.46609 1.91862   1.000 32.39768  ? 114 ALA H HA   1 
ATOM   1742 H HB1  . ALA A 1 118 ? 5.31547   -18.49103 2.02120   1.000 39.62381  ? 114 ALA H HB1  1 
ATOM   1743 H HB2  . ALA A 1 118 ? 3.77611   -18.17833 2.25804   1.000 39.62381  ? 114 ALA H HB2  1 
ATOM   1744 H HB3  . ALA A 1 118 ? 4.77526   -18.22936 3.49199   1.000 39.62381  ? 114 ALA H HB3  1 
ATOM   1745 N N    . SER A 1 119 ? 6.50236   -20.97309 2.35890   1.000 29.24170  ? 115 SER H N    1 
ATOM   1746 C CA   . SER A 1 119 ? 7.78254   -21.59565 2.66992   1.000 32.61527  ? 115 SER H CA   1 
ATOM   1747 C C    . SER A 1 119 ? 8.76654   -20.54344 3.16033   1.000 22.51626  ? 115 SER H C    1 
ATOM   1748 O O    . SER A 1 119 ? 8.69286   -19.37500 2.77130   1.000 27.62828  ? 115 SER H O    1 
ATOM   1749 C CB   . SER A 1 119 ? 8.35836   -22.29925 1.43710   1.000 40.31127  ? 115 SER H CB   1 
ATOM   1750 O OG   . SER A 1 119 ? 7.55674   -23.40461 1.04962   1.000 46.10075  ? 115 SER H OG   1 
ATOM   1751 H H    . SER A 1 119 ? 6.43445   -20.71303 1.54199   1.000 35.09688  ? 115 SER H H    1 
ATOM   1752 H HA   . SER A 1 119 ? 7.65897   -22.25925 3.36652   1.000 39.14516  ? 115 SER H HA   1 
ATOM   1753 H HB2  . SER A 1 119 ? 8.39489   -21.66598 0.70325   1.000 48.38036  ? 115 SER H HB2  1 
ATOM   1754 H HB3  . SER A 1 119 ? 9.25074   -22.61706 1.64580   1.000 48.38036  ? 115 SER H HB3  1 
ATOM   1755 H HG   . SER A 1 119 ? 7.88183   -23.76983 0.36660   1.000 55.32774  ? 115 SER H HG   1 
ATOM   1756 N N    . THR A 1 120 ? 9.69826   -20.96023 4.01338   1.000 27.44361  ? 116 THR H N    1 
ATOM   1757 C CA   . THR A 1 120 ? 10.75154  -20.03840 4.40472   1.000 21.99186  ? 116 THR H CA   1 
ATOM   1758 C C    . THR A 1 120 ? 11.69787  -19.82925 3.22980   1.000 27.84088  ? 116 THR H C    1 
ATOM   1759 O O    . THR A 1 120 ? 11.88918  -20.71097 2.38803   1.000 31.05565  ? 116 THR H O    1 
ATOM   1760 C CB   . THR A 1 120 ? 11.53276  -20.53976 5.62500   1.000 31.12309  ? 116 THR H CB   1 
ATOM   1761 O OG1  . THR A 1 120 ? 12.25912  -21.72254 5.29084   1.000 41.91225  ? 116 THR H OG1  1 
ATOM   1762 C CG2  . THR A 1 120 ? 10.60243  -20.84657 6.77969   1.000 33.85978  ? 116 THR H CG2  1 
ATOM   1763 H H    . THR A 1 120 ? 9.73904   -21.74377 4.36553   1.000 32.93917  ? 116 THR H H    1 
ATOM   1764 H HA   . THR A 1 120 ? 10.35557  -19.19103 4.66178   1.000 26.39707  ? 116 THR H HA   1 
ATOM   1765 H HB   . THR A 1 120 ? 12.15037  -19.84549 5.90327   1.000 37.35454  ? 116 THR H HB   1 
ATOM   1766 H HG1  . THR A 1 120 ? 11.72907  -22.32391 5.03983   1.000 50.30154  ? 116 THR H HG1  1 
ATOM   1767 H HG21 . THR A 1 120 ? 11.11488  -21.13602 7.55073   1.000 40.63857  ? 116 THR H HG21 1 
ATOM   1768 H HG22 . THR A 1 120 ? 10.09631  -20.05400 7.01757   1.000 40.63857  ? 116 THR H HG22 1 
ATOM   1769 H HG23 . THR A 1 120 ? 9.98461   -21.55134 6.52971   1.000 40.63857  ? 116 THR H HG23 1 
ATOM   1770 N N    . LYS A 1 121 ? 12.28285  -18.63984 3.17528   1.000 20.89195  ? 117 LYS H N    1 
ATOM   1771 C CA   . LYS A 1 121 ? 13.21230  -18.27325 2.11580   1.000 23.88965  ? 117 LYS H CA   1 
ATOM   1772 C C    . LYS A 1 121 ? 14.27557  -17.38179 2.72974   1.000 18.91395  ? 117 LYS H C    1 
ATOM   1773 O O    . LYS A 1 121 ? 13.94767  -16.37110 3.36035   1.000 19.07526  ? 117 LYS H O    1 
ATOM   1774 C CB   . LYS A 1 121 ? 12.49401  -17.55653 0.96733   1.000 26.80783  ? 117 LYS H CB   1 
ATOM   1775 C CG   . LYS A 1 121 ? 13.42427  -17.05077 -0.13355  1.000 27.13276  ? 117 LYS H CG   1 
ATOM   1776 C CD   . LYS A 1 121 ? 12.64987  -16.33417 -1.23293  1.000 35.99639  ? 117 LYS H CD   1 
ATOM   1777 C CE   . LYS A 1 121 ? 13.55504  -15.91177 -2.39094  1.000 33.31637  ? 117 LYS H CE   1 
ATOM   1778 N NZ   . LYS A 1 121 ? 14.93315  -15.53715 -1.95121  1.000 40.28724  ? 117 LYS H NZ   1 
ATOM   1779 H H    . LYS A 1 121 ? 12.15486  -18.01519 3.75238   1.000 25.07718  ? 117 LYS H H    1 
ATOM   1780 H HA   . LYS A 1 121 ? 13.63554  -19.06607 1.75082   1.000 28.67441  ? 117 LYS H HA   1 
ATOM   1781 H HB2  . LYS A 1 121 ? 11.86566  -18.17387 0.56117   1.000 32.17623  ? 117 LYS H HB2  1 
ATOM   1782 H HB3  . LYS A 1 121 ? 12.02057  -16.79042 1.32765   1.000 32.17623  ? 117 LYS H HB3  1 
ATOM   1783 H HG2  . LYS A 1 121 ? 14.06233  -16.42673 0.24640   1.000 32.56615  ? 117 LYS H HG2  1 
ATOM   1784 H HG3  . LYS A 1 121 ? 13.89146  -17.80268 -0.53012  1.000 32.56615  ? 117 LYS H HG3  1 
ATOM   1785 H HD2  . LYS A 1 121 ? 11.96839  -16.92905 -1.58308  1.000 43.20250  ? 117 LYS H HD2  1 
ATOM   1786 H HD3  . LYS A 1 121 ? 12.23728  -15.53705 -0.86515  1.000 43.20250  ? 117 LYS H HD3  1 
ATOM   1787 H HE2  . LYS A 1 121 ? 13.63164  -16.64944 -3.01614  1.000 39.98647  ? 117 LYS H HE2  1 
ATOM   1788 H HE3  . LYS A 1 121 ? 13.16325  -15.14203 -2.83242  1.000 39.98647  ? 117 LYS H HE3  1 
ATOM   1789 H HZ1  . LYS A 1 121 ? 15.38273  -15.17915 -2.63079  1.000 48.35152  ? 117 LYS H HZ1  1 
ATOM   1790 H HZ2  . LYS A 1 121 ? 14.89068  -14.94433 -1.28875  1.000 48.35152  ? 117 LYS H HZ2  1 
ATOM   1791 H HZ3  . LYS A 1 121 ? 15.36824  -16.25902 -1.66538  1.000 48.35152  ? 117 LYS H HZ3  1 
ATOM   1792 N N    . GLY A 1 122 ? 15.53679  -17.76984 2.56738   1.000 17.15930  ? 118 GLY H N    1 
ATOM   1793 C CA   . GLY A 1 122 ? 16.64635  -16.99955 3.06966   1.000 19.90841  ? 118 GLY H CA   1 
ATOM   1794 C C    . GLY A 1 122 ? 16.90248  -15.78085 2.20894   1.000 20.83389  ? 118 GLY H C    1 
ATOM   1795 O O    . GLY A 1 122 ? 16.55951  -15.75027 1.02369   1.000 19.46250  ? 118 GLY H O    1 
ATOM   1796 H H    . GLY A 1 122 ? 15.77115  -18.49052 2.16083   1.000 20.59800  ? 118 GLY H H    1 
ATOM   1797 H HA2  . GLY A 1 122 ? 16.45591  -16.70619 3.97441   1.000 23.89692  ? 118 GLY H HA2  1 
ATOM   1798 H HA3  . GLY A 1 122 ? 17.44640  -17.54796 3.07729   1.000 23.89692  ? 118 GLY H HA3  1 
ATOM   1799 N N    . PRO A 1 123 ? 17.51584  -14.75289 2.78579   1.000 19.13942  ? 119 PRO H N    1 
ATOM   1800 C CA   . PRO A 1 123 ? 17.68976  -13.49729 2.05315   1.000 20.38017  ? 119 PRO H CA   1 
ATOM   1801 C C    . PRO A 1 123 ? 18.85384  -13.53582 1.07976   1.000 23.22979  ? 119 PRO H C    1 
ATOM   1802 O O    . PRO A 1 123 ? 19.81905  -14.28225 1.24576   1.000 18.63630  ? 119 PRO H O    1 
ATOM   1803 C CB   . PRO A 1 123 ? 17.96613  -12.48324 3.16832   1.000 20.06743  ? 119 PRO H CB   1 
ATOM   1804 C CG   . PRO A 1 123 ? 18.69909  -13.29411 4.20061   1.000 21.13248  ? 119 PRO H CG   1 
ATOM   1805 C CD   . PRO A 1 123 ? 18.08672  -14.68138 4.14611   1.000 23.58011  ? 119 PRO H CD   1 
ATOM   1806 H HA   . PRO A 1 123 ? 16.87599  -13.27274 1.57539   1.000 24.46304  ? 119 PRO H HA   1 
ATOM   1807 H HB2  . PRO A 1 123 ? 18.51549  -11.75683 2.83451   1.000 24.08775  ? 119 PRO H HB2  1 
ATOM   1808 H HB3  . PRO A 1 123 ? 17.13242  -12.13401 3.52025   1.000 24.08775  ? 119 PRO H HB3  1 
ATOM   1809 H HG2  . PRO A 1 123 ? 19.64353  -13.32629 3.98176   1.000 25.36582  ? 119 PRO H HG2  1 
ATOM   1810 H HG3  . PRO A 1 123 ? 18.57498  -12.89766 5.07715   1.000 25.36582  ? 119 PRO H HG3  1 
ATOM   1811 H HD2  . PRO A 1 123 ? 18.76570  -15.36277 4.27100   1.000 28.30296  ? 119 PRO H HD2  1 
ATOM   1812 H HD3  . PRO A 1 123 ? 17.39244  -14.77803 4.81657   1.000 28.30296  ? 119 PRO H HD3  1 
ATOM   1813 N N    . SER A 1 124 ? 18.75376  -12.69703 0.05858   1.000 19.14309  ? 120 SER H N    1 
ATOM   1814 C CA   . SER A 1 124 ? 19.91003  -12.30793 -0.73541  1.000 23.97629  ? 120 SER H CA   1 
ATOM   1815 C C    . SER A 1 124 ? 20.43211  -10.99943 -0.16340  1.000 18.28761  ? 120 SER H C    1 
ATOM   1816 O O    . SER A 1 124 ? 19.64745  -10.14654 0.25171   1.000 20.75214  ? 120 SER H O    1 
ATOM   1817 C CB   . SER A 1 124 ? 19.54496  -12.14608 -2.21092  1.000 28.12149  ? 120 SER H CB   1 
ATOM   1818 O OG   . SER A 1 124 ? 18.92595  -13.32154 -2.71445  1.000 34.86346  ? 120 SER H OG   1 
ATOM   1819 H H    . SER A 1 124 ? 18.01689  -12.33499 -0.19745  1.000 22.97854  ? 120 SER H H    1 
ATOM   1820 H HA   . SER A 1 124 ? 20.60426  -12.98430 -0.69708  1.000 28.77838  ? 120 SER H HA   1 
ATOM   1821 H HB2  . SER A 1 124 ? 18.92994  -11.40172 -2.30351  1.000 33.75262  ? 120 SER H HB2  1 
ATOM   1822 H HB3  . SER A 1 124 ? 20.35340  -11.97358 -2.71843  1.000 33.75262  ? 120 SER H HB3  1 
ATOM   1823 H HG   . SER A 1 124 ? 18.70929  -13.21030 -3.51837  1.000 41.84298  ? 120 SER H HG   1 
ATOM   1824 N N    . VAL A 1 125 ? 21.74983  -10.84735 -0.10764  1.000 18.02030  ? 121 VAL H N    1 
ATOM   1825 C CA   . VAL A 1 125 ? 22.36384  -9.63351  0.41895   1.000 17.81172  ? 121 VAL H CA   1 
ATOM   1826 C C    . VAL A 1 125 ? 23.20271  -8.99372  -0.68103  1.000 20.24885  ? 121 VAL H C    1 
ATOM   1827 O O    . VAL A 1 125 ? 24.06640  -9.65066  -1.27479  1.000 18.65297  ? 121 VAL H O    1 
ATOM   1828 C CB   . VAL A 1 125 ? 23.21374  -9.92326  1.66906   1.000 17.23561  ? 121 VAL H CB   1 
ATOM   1829 C CG1  . VAL A 1 125 ? 23.84441  -8.64775  2.18866   1.000 19.75359  ? 121 VAL H CG1  1 
ATOM   1830 C CG2  . VAL A 1 125 ? 22.36011  -10.57036 2.74779   1.000 17.68512  ? 121 VAL H CG2  1 
ATOM   1831 H H    . VAL A 1 125 ? 22.31480  -11.43954 -0.37166  1.000 21.63120  ? 121 VAL H H    1 
ATOM   1832 H HA   . VAL A 1 125 ? 21.66714  -9.00500  0.66488   1.000 21.38090  ? 121 VAL H HA   1 
ATOM   1833 H HB   . VAL A 1 125 ? 23.92517  -10.53806 1.43075   1.000 20.68956  ? 121 VAL H HB   1 
ATOM   1834 H HG11 . VAL A 1 125 ? 24.21225  -8.81389  3.07070   1.000 23.71114  ? 121 VAL H HG11 1 
ATOM   1835 H HG12 . VAL A 1 125 ? 24.55025  -8.37457  1.58199   1.000 23.71114  ? 121 VAL H HG12 1 
ATOM   1836 H HG13 . VAL A 1 125 ? 23.16515  -7.95706  2.23827   1.000 23.71114  ? 121 VAL H HG13 1 
ATOM   1837 H HG21 . VAL A 1 125 ? 22.89998  -10.69798 3.54350   1.000 21.22898  ? 121 VAL H HG21 1 
ATOM   1838 H HG22 . VAL A 1 125 ? 21.60928  -9.98949  2.94714   1.000 21.22898  ? 121 VAL H HG22 1 
ATOM   1839 H HG23 . VAL A 1 125 ? 22.03909  -11.42689 2.42500   1.000 21.22898  ? 121 VAL H HG23 1 
ATOM   1840 N N    . PHE A 1 126 ? 22.94663  -7.71903  -0.94799  1.000 17.89312  ? 122 PHE H N    1 
ATOM   1841 C CA   . PHE A 1 126 ? 23.64478  -6.97661  -1.98591  1.000 20.59333  ? 122 PHE H CA   1 
ATOM   1842 C C    . PHE A 1 126 ? 24.26193  -5.71451  -1.40637  1.000 15.87316  ? 122 PHE H C    1 
ATOM   1843 O O    . PHE A 1 126 ? 23.69737  -5.10189  -0.49520  1.000 15.97483  ? 122 PHE H O    1 
ATOM   1844 C CB   . PHE A 1 126 ? 22.69620  -6.58476  -3.12929  1.000 17.65106  ? 122 PHE H CB   1 
ATOM   1845 C CG   . PHE A 1 126 ? 21.96526  -7.74240  -3.73806  1.000 18.82979  ? 122 PHE H CG   1 
ATOM   1846 C CD1  . PHE A 1 126 ? 22.64918  -8.72796  -4.43185  1.000 18.97755  ? 122 PHE H CD1  1 
ATOM   1847 C CD2  . PHE A 1 126 ? 20.58631  -7.83562  -3.63773  1.000 20.12153  ? 122 PHE H CD2  1 
ATOM   1848 C CE1  . PHE A 1 126 ? 21.97544  -9.78678  -4.99804  1.000 19.63033  ? 122 PHE H CE1  1 
ATOM   1849 C CE2  . PHE A 1 126 ? 19.90639  -8.89655  -4.20981  1.000 19.06218  ? 122 PHE H CE2  1 
ATOM   1850 C CZ   . PHE A 1 126 ? 20.59802  -9.87277  -4.88373  1.000 18.73373  ? 122 PHE H CZ   1 
ATOM   1851 H H    . PHE A 1 126 ? 22.35765  -7.25203  -0.53011  1.000 21.47858  ? 122 PHE H H    1 
ATOM   1852 H HA   . PHE A 1 126 ? 24.35405  -7.53114  -2.34692  1.000 24.71883  ? 122 PHE H HA   1 
ATOM   1853 H HB2  . PHE A 1 126 ? 22.03366  -5.96541  -2.78528  1.000 21.18810  ? 122 PHE H HB2  1 
ATOM   1854 H HB3  . PHE A 1 126 ? 23.21394  -6.16055  -3.83135  1.000 21.18810  ? 122 PHE H HB3  1 
ATOM   1855 H HD1  . PHE A 1 126 ? 23.57377  -8.67354  -4.51597  1.000 22.77989  ? 122 PHE H HD1  1 
ATOM   1856 H HD2  . PHE A 1 126 ? 20.11276  -7.17824  -3.18110  1.000 24.15267  ? 122 PHE H HD2  1 
ATOM   1857 H HE1  . PHE A 1 126 ? 22.44563  -10.44460 -5.45749  1.000 23.56322  ? 122 PHE H HE1  1 
ATOM   1858 H HE2  . PHE A 1 126 ? 18.98064  -8.94837  -4.13779  1.000 22.88145  ? 122 PHE H HE2  1 
ATOM   1859 H HZ   . PHE A 1 126 ? 20.14262  -10.58980 -5.26240  1.000 22.48731  ? 122 PHE H HZ   1 
ATOM   1860 N N    . PRO A 1 127 ? 25.40042  -5.27895  -1.93549  1.000 14.02379  ? 123 PRO H N    1 
ATOM   1861 C CA   . PRO A 1 127 ? 26.04927  -4.08524  -1.38281  1.000 16.69898  ? 123 PRO H CA   1 
ATOM   1862 C C    . PRO A 1 127 ? 25.41494  -2.79971  -1.88552  1.000 20.38580  ? 123 PRO H C    1 
ATOM   1863 O O    . PRO A 1 127 ? 24.99324  -2.69409  -3.04038  1.000 22.85286  ? 123 PRO H O    1 
ATOM   1864 C CB   . PRO A 1 127 ? 27.49556  -4.21760  -1.87716  1.000 20.21329  ? 123 PRO H CB   1 
ATOM   1865 C CG   . PRO A 1 127 ? 27.35557  -4.91707  -3.19501  1.000 22.90289  ? 123 PRO H CG   1 
ATOM   1866 C CD   . PRO A 1 127 ? 26.18155  -5.86488  -3.04039  1.000 19.14531  ? 123 PRO H CD   1 
ATOM   1867 H HA   . PRO A 1 127 ? 26.02187  -4.09825  -0.41328  1.000 20.04560  ? 123 PRO H HA   1 
ATOM   1868 H HB2  . PRO A 1 127 ? 27.89512  -3.34030  -1.98485  1.000 24.26278  ? 123 PRO H HB2  1 
ATOM   1869 H HB3  . PRO A 1 127 ? 28.01700  -4.74518  -1.25213  1.000 24.26278  ? 123 PRO H HB3  1 
ATOM   1870 H HG2  . PRO A 1 127 ? 27.18204  -4.26671  -3.89345  1.000 27.49031  ? 123 PRO H HG2  1 
ATOM   1871 H HG3  . PRO A 1 127 ? 28.16883  -5.40736  -3.39286  1.000 27.49031  ? 123 PRO H HG3  1 
ATOM   1872 H HD2  . PRO A 1 127 ? 25.65523  -5.89530  -3.85462  1.000 22.98121  ? 123 PRO H HD2  1 
ATOM   1873 H HD3  . PRO A 1 127 ? 26.48765  -6.75594  -2.80973  1.000 22.98121  ? 123 PRO H HD3  1 
ATOM   1874 N N    . LEU A 1 128 ? 25.32638  -1.82568  -0.98516  1.000 18.35826  ? 124 LEU H N    1 
ATOM   1875 C CA   . LEU A 1 128 ? 25.05317  -0.42927  -1.31303  1.000 22.62846  ? 124 LEU H CA   1 
ATOM   1876 C C    . LEU A 1 128 ? 26.41293  0.24499   -1.16525  1.000 22.91330  ? 124 LEU H C    1 
ATOM   1877 O O    . LEU A 1 128 ? 26.80351  0.66236   -0.07334  1.000 19.08260  ? 124 LEU H O    1 
ATOM   1878 C CB   . LEU A 1 128 ? 23.99264  0.16432   -0.39318  1.000 21.40424  ? 124 LEU H CB   1 
ATOM   1879 C CG   . LEU A 1 128 ? 22.63105  -0.54248  -0.42913  1.000 20.64072  ? 124 LEU H CG   1 
ATOM   1880 C CD1  . LEU A 1 128 ? 21.73263  -0.10253  0.72722   1.000 22.65541  ? 124 LEU H CD1  1 
ATOM   1881 C CD2  . LEU A 1 128 ? 21.92814  -0.31435  -1.76267  1.000 20.10287  ? 124 LEU H CD2  1 
ATOM   1882 H H    . LEU A 1 128 ? 25.42511  -1.95417  -0.14056  1.000 22.03675  ? 124 LEU H H    1 
ATOM   1883 H HA   . LEU A 1 128 ? 24.71194  -0.32590  -2.21512  1.000 27.16098  ? 124 LEU H HA   1 
ATOM   1884 H HB2  . LEU A 1 128 ? 24.31948  0.12040   0.51904   1.000 25.69192  ? 124 LEU H HB2  1 
ATOM   1885 H HB3  . LEU A 1 128 ? 23.84778  1.08854   -0.64955  1.000 25.69192  ? 124 LEU H HB3  1 
ATOM   1886 H HG   . LEU A 1 128 ? 22.79155  -1.49388  -0.32929  1.000 24.77570  ? 124 LEU H HG   1 
ATOM   1887 H HD11 . LEU A 1 128 ? 20.88550  -0.57090  0.66482   1.000 27.19332  ? 124 LEU H HD11 1 
ATOM   1888 H HD12 . LEU A 1 128 ? 22.16907  -0.31863  1.56610   1.000 27.19332  ? 124 LEU H HD12 1 
ATOM   1889 H HD13 . LEU A 1 128 ? 21.58665  0.85454   0.66724   1.000 27.19332  ? 124 LEU H HD13 1 
ATOM   1890 H HD21 . LEU A 1 128 ? 21.05964  -0.74572  -1.73973  1.000 24.13028  ? 124 LEU H HD21 1 
ATOM   1891 H HD22 . LEU A 1 128 ? 21.82021  0.63926   -1.90369  1.000 24.13028  ? 124 LEU H HD22 1 
ATOM   1892 H HD23 . LEU A 1 128 ? 22.46779  -0.69481  -2.47325  1.000 24.13028  ? 124 LEU H HD23 1 
ATOM   1893 N N    . ALA A 1 129 ? 27.15920  0.29508   -2.27005  1.000 24.11893  ? 125 ALA H N    1 
ATOM   1894 C CA   . ALA A 1 129 ? 28.57351  0.62177   -2.19137  1.000 26.28909  ? 125 ALA H CA   1 
ATOM   1895 C C    . ALA A 1 129 ? 28.76491  2.12760   -2.04345  1.000 32.11671  ? 125 ALA H C    1 
ATOM   1896 O O    . ALA A 1 129 ? 28.07595  2.90591   -2.70433  1.000 26.71199  ? 125 ALA H O    1 
ATOM   1897 C CB   . ALA A 1 129 ? 29.30760  0.13477   -3.43644  1.000 30.55142  ? 125 ALA H CB   1 
ATOM   1898 H H    . ALA A 1 129 ? 26.87004  0.14510   -3.06597  1.000 28.94955  ? 125 ALA H H    1 
ATOM   1899 H HA   . ALA A 1 129 ? 28.95985  0.18532   -1.41603  1.000 31.55374  ? 125 ALA H HA   1 
ATOM   1900 H HB1  . ALA A 1 129 ? 30.24722  0.36265   -3.35843  1.000 36.66854  ? 125 ALA H HB1  1 
ATOM   1901 H HB2  . ALA A 1 129 ? 29.20532  -0.82721  -3.50733  1.000 36.66854  ? 125 ALA H HB2  1 
ATOM   1902 H HB3  . ALA A 1 129 ? 28.92626  0.56637   -4.21695  1.000 36.66854  ? 125 ALA H HB3  1 
ATOM   1903 N N    . PRO A 1 130 ? 29.69932  2.56485   -1.19777  1.000 33.94484  ? 126 PRO H N    1 
ATOM   1904 C CA   . PRO A 1 130 ? 29.99873  4.00040   -1.12417  1.000 42.47039  ? 126 PRO H CA   1 
ATOM   1905 C C    . PRO A 1 130 ? 30.60217  4.46844   -2.43803  1.000 42.39290  ? 126 PRO H C    1 
ATOM   1906 O O    . PRO A 1 130 ? 31.47702  3.80812   -3.00101  1.000 49.00433  ? 126 PRO H O    1 
ATOM   1907 C CB   . PRO A 1 130 ? 31.00395  4.09637   0.02828   1.000 36.34013  ? 126 PRO H CB   1 
ATOM   1908 C CG   . PRO A 1 130 ? 31.71501  2.78164   -0.01014  1.000 34.55418  ? 126 PRO H CG   1 
ATOM   1909 C CD   . PRO A 1 130 ? 30.65920  1.76826   -0.40911  1.000 34.77860  ? 126 PRO H CD   1 
ATOM   1910 H HA   . PRO A 1 130 ? 29.20975  4.52181   -0.90845  1.000 50.97130  ? 126 PRO H HA   1 
ATOM   1911 H HB2  . PRO A 1 130 ? 31.61738  4.83250   -0.12240  1.000 43.61499  ? 126 PRO H HB2  1 
ATOM   1912 H HB3  . PRO A 1 130 ? 30.53805  4.21975   0.87007   1.000 43.61499  ? 126 PRO H HB3  1 
ATOM   1913 H HG2  . PRO A 1 130 ? 32.42965  2.81249   -0.66530  1.000 41.47185  ? 126 PRO H HG2  1 
ATOM   1914 H HG3  . PRO A 1 130 ? 32.07696  2.57698   0.86622   1.000 41.47185  ? 126 PRO H HG3  1 
ATOM   1915 H HD2  . PRO A 1 130 ? 31.04640  1.06166   -0.94921  1.000 41.74116  ? 126 PRO H HD2  1 
ATOM   1916 H HD3  . PRO A 1 130 ? 30.23103  1.38992   0.37474   1.000 41.74116  ? 126 PRO H HD3  1 
ATOM   1917 N N    . SER A 1 131 ? 30.11835  5.60383   -2.93372  1.000 56.47329  ? 127 SER H N    1 
ATOM   1918 C CA   . SER A 1 131 ? 30.63787  6.14857   -4.18134  1.000 69.00022  ? 127 SER H CA   1 
ATOM   1919 C C    . SER A 1 131 ? 32.14192  6.36174   -4.06686  1.000 74.11193  ? 127 SER H C    1 
ATOM   1920 O O    . SER A 1 131 ? 32.59529  7.19965   -3.28057  1.000 70.85901  ? 127 SER H O    1 
ATOM   1921 C CB   . SER A 1 131 ? 29.93393  7.46134   -4.53290  1.000 77.38477  ? 127 SER H CB   1 
ATOM   1922 O OG   . SER A 1 131 ? 30.38082  7.96122   -5.78242  1.000 77.56237  ? 127 SER H OG   1 
ATOM   1923 H H    . SER A 1 131 ? 29.49562  6.07194   -2.56946  1.000 67.77479  ? 127 SER H H    1 
ATOM   1924 H HA   . SER A 1 131 ? 30.46720  5.52404   -4.90365  1.000 82.80710  ? 127 SER H HA   1 
ATOM   1925 H HB2  . SER A 1 131 ? 28.97815  7.30296   -4.58087  1.000 92.86856  ? 127 SER H HB2  1 
ATOM   1926 H HB3  . SER A 1 131 ? 30.12750  8.11653   -3.84432  1.000 92.86856  ? 127 SER H HB3  1 
ATOM   1927 H HG   . SER A 1 131 ? 29.96541  8.66536   -5.97535  1.000 93.08167  ? 127 SER H HG   1 
ATOM   1928 N N    . SER A 1 132 ? 32.92527  5.59091   -4.82722  1.000 84.73541  ? 128 SER H N    1 
ATOM   1929 C CA   . SER A 1 132 ? 34.36808  5.81239   -4.85165  1.000 88.15557  ? 128 SER H CA   1 
ATOM   1930 C C    . SER A 1 132 ? 34.69386  7.20997   -5.36005  1.000 92.74567  ? 128 SER H C    1 
ATOM   1931 O O    . SER A 1 132 ? 35.68206  7.81670   -4.92917  1.000 90.38181  ? 128 SER H O    1 
ATOM   1932 C CB   . SER A 1 132 ? 35.05002  4.74528   -5.70935  1.000 74.60530  ? 128 SER H CB   1 
ATOM   1933 O OG   . SER A 1 132 ? 34.26280  4.41443   -6.84128  1.000 68.28486  ? 128 SER H OG   1 
ATOM   1934 H H    . SER A 1 132 ? 32.65025  4.94722   -5.32685  1.000 101.68932 ? 128 SER H H    1 
ATOM   1935 H HA   . SER A 1 132 ? 34.72245  5.72914   -3.95255  1.000 105.79351 ? 128 SER H HA   1 
ATOM   1936 H HB2  . SER A 1 132 ? 35.90679  5.08541   -6.01128  1.000 89.53320  ? 128 SER H HB2  1 
ATOM   1937 H HB3  . SER A 1 132 ? 35.18008  3.94742   -5.17325  1.000 89.53320  ? 128 SER H HB3  1 
ATOM   1938 H HG   . SER A 1 132 ? 34.71918  3.96968   -7.38856  1.000 81.94867  ? 128 SER H HG   1 
ATOM   1939 N N    . LYS A 1 133 ? 33.87710  7.73348   -6.27471  1.000 84.03104  ? 129 LYS H N    1 
ATOM   1940 C CA   . LYS A 1 133 ? 33.86259  9.16068   -6.58868  1.000 82.47797  ? 129 LYS H CA   1 
ATOM   1941 C C    . LYS A 1 133 ? 32.99344  9.87976   -5.54972  1.000 78.09412  ? 129 LYS H C    1 
ATOM   1942 O O    . LYS A 1 133 ? 32.02557  10.57254  -5.86402  1.000 72.35541  ? 129 LYS H O    1 
ATOM   1943 C CB   . LYS A 1 133 ? 33.35489  9.38200   -8.00803  1.000 85.95205  ? 129 LYS H CB   1 
ATOM   1944 C CG   . LYS A 1 133 ? 34.30668  10.14369  -8.93264  1.000 89.12744  ? 129 LYS H CG   1 
ATOM   1945 C CD   . LYS A 1 133 ? 33.55850  10.63055  -10.18215 1.000 83.67710  ? 129 LYS H CD   1 
ATOM   1946 C CE   . LYS A 1 133 ? 34.31911  10.41624  -11.49721 1.000 70.12695  ? 129 LYS H CE   1 
ATOM   1947 N NZ   . LYS A 1 133 ? 35.13521  9.16837   -11.55850 1.000 66.84362  ? 129 LYS H NZ   1 
ATOM   1948 H H    . LYS A 1 133 ? 33.31321  7.27439   -6.73391  1.000 100.84409 ? 129 LYS H H    1 
ATOM   1949 H HA   . LYS A 1 133 ? 34.76229  9.52114   -6.54981  1.000 98.98040  ? 129 LYS H HA   1 
ATOM   1950 H HB2  . LYS A 1 133 ? 33.19025  8.51576   -8.41228  1.000 103.14929 ? 129 LYS H HB2  1 
ATOM   1951 H HB3  . LYS A 1 133 ? 32.52913  9.88883   -7.96171  1.000 103.14929 ? 129 LYS H HB3  1 
ATOM   1952 H HG2  . LYS A 1 133 ? 34.66641  10.91463  -8.46665  1.000 106.95976 ? 129 LYS H HG2  1 
ATOM   1953 H HG3  . LYS A 1 133 ? 35.02807  9.55833   -9.21167  1.000 106.95976 ? 129 LYS H HG3  1 
ATOM   1954 H HD2  . LYS A 1 133 ? 32.71846  10.15005  -10.24800 1.000 100.41935 ? 129 LYS H HD2  1 
ATOM   1955 H HD3  . LYS A 1 133 ? 33.39052  11.58168  -10.09260 1.000 100.41935 ? 129 LYS H HD3  1 
ATOM   1956 H HE2  . LYS A 1 133 ? 33.67555  10.37772  -12.22195 1.000 84.15918  ? 129 LYS H HE2  1 
ATOM   1957 H HE3  . LYS A 1 133 ? 34.92260  11.16416  -11.62884 1.000 84.15918  ? 129 LYS H HE3  1 
ATOM   1958 H HZ1  . LYS A 1 133 ? 35.88558  9.27214   -11.09130 1.000 80.21918  ? 129 LYS H HZ1  1 
ATOM   1959 H HZ2  . LYS A 1 133 ? 34.67508  8.48672   -11.21830 1.000 80.21918  ? 129 LYS H HZ2  1 
ATOM   1960 H HZ3  . LYS A 1 133 ? 35.34437  8.98263   -12.40340 1.000 80.21918  ? 129 LYS H HZ3  1 
ATOM   1961 N N    . SER A 1 134 ? 33.36395  9.68345   -4.28021  1.000 86.82701  ? 130 SER H N    1 
ATOM   1962 C CA   . SER A 1 134 ? 32.52095  10.09126  -3.16019  1.000 91.67357  ? 130 SER H CA   1 
ATOM   1963 C C    . SER A 1 134 ? 32.02935  11.51913  -3.34319  1.000 80.01645  ? 130 SER H C    1 
ATOM   1964 O O    . SER A 1 134 ? 32.76267  12.38912  -3.82066  1.000 72.55322  ? 130 SER H O    1 
ATOM   1965 C CB   . SER A 1 134 ? 33.28964  9.96457   -1.84168  1.000 83.06582  ? 130 SER H CB   1 
ATOM   1966 O OG   . SER A 1 134 ? 32.49040  10.36822  -0.74076  1.000 65.04472  ? 130 SER H OG   1 
ATOM   1967 H H    . SER A 1 134 ? 34.10321  9.31401   -4.04228  1.000 104.19925 ? 130 SER H H    1 
ATOM   1968 H HA   . SER A 1 134 ? 31.74776  9.50705   -3.11806  1.000 110.01512 ? 130 SER H HA   1 
ATOM   1969 H HB2  . SER A 1 134 ? 33.55073  9.03862   -1.71779  1.000 99.68581  ? 130 SER H HB2  1 
ATOM   1970 H HB3  . SER A 1 134 ? 34.07756  10.52891  -1.88173  1.000 99.68581  ? 130 SER H HB3  1 
ATOM   1971 H HG   . SER A 1 134 ? 32.91594  10.26548  -0.02385  1.000 78.06049  ? 130 SER H HG   1 
ATOM   1972 N N    . THR A 1 135 ? 30.77529  11.75608  -2.94856  1.000 75.63432  ? 131 THR H N    1 
ATOM   1973 C CA   . THR A 1 135 ? 30.07844  12.98942  -3.29315  1.000 71.12153  ? 131 THR H CA   1 
ATOM   1974 C C    . THR A 1 135 ? 29.53468  13.73143  -2.07535  1.000 73.83235  ? 131 THR H C    1 
ATOM   1975 O O    . THR A 1 135 ? 28.65777  14.58998  -2.22514  1.000 65.35658  ? 131 THR H O    1 
ATOM   1976 C CB   . THR A 1 135 ? 28.94322  12.68682  -4.27551  1.000 75.14259  ? 131 THR H CB   1 
ATOM   1977 O OG1  . THR A 1 135 ? 28.96280  11.29409  -4.62223  1.000 81.63197  ? 131 THR H OG1  1 
ATOM   1978 C CG2  . THR A 1 135 ? 29.10452  13.51326  -5.53547  1.000 64.60394  ? 131 THR H CG2  1 
ATOM   1979 H H    . THR A 1 135 ? 30.30680  11.21069  -2.47667  1.000 90.76802  ? 131 THR H H    1 
ATOM   1980 H HA   . THR A 1 135 ? 30.71445  13.58447  -3.72014  1.000 85.35267  ? 131 THR H HA   1 
ATOM   1981 H HB   . THR A 1 135 ? 28.09235  12.90648  -3.86482  1.000 90.17794  ? 131 THR H HB   1 
ATOM   1982 H HG1  . THR A 1 135 ? 28.34838  11.12565  -5.16969  1.000 97.96520  ? 131 THR H HG1  1 
ATOM   1983 H HG21 . THR A 1 135 ? 28.29821  13.46080  -6.07214  1.000 77.53157  ? 131 THR H HG21 1 
ATOM   1984 H HG22 . THR A 1 135 ? 29.26940  14.44092  -5.30491  1.000 77.53157  ? 131 THR H HG22 1 
ATOM   1985 H HG23 . THR A 1 135 ? 29.85188  13.18085  -6.05686  1.000 77.53157  ? 131 THR H HG23 1 
ATOM   1986 N N    . SER A 1 136 ? 30.04405  13.44435  -0.87646  1.000 67.32947  ? 132 SER H N    1 
ATOM   1987 C CA   . SER A 1 136 ? 29.59042  14.14122  0.32459   1.000 60.63873  ? 132 SER H CA   1 
ATOM   1988 C C    . SER A 1 136 ? 30.77687  14.53659  1.19135   1.000 59.41018  ? 132 SER H C    1 
ATOM   1989 O O    . SER A 1 136 ? 30.75284  14.38883  2.41832   1.000 55.86807  ? 132 SER H O    1 
ATOM   1990 C CB   . SER A 1 136 ? 28.59800  13.29154  1.11821   1.000 66.26583  ? 132 SER H CB   1 
ATOM   1991 O OG   . SER A 1 136 ? 27.86028  14.09016  2.02994   1.000 58.30685  ? 132 SER H OG   1 
ATOM   1992 H H    . SER A 1 136 ? 30.65113  12.85175  -0.73546  1.000 80.80220  ? 132 SER H H    1 
ATOM   1993 H HA   . SER A 1 136 ? 29.13797  14.95536  0.05373   1.000 72.77331  ? 132 SER H HA   1 
ATOM   1994 H HB2  . SER A 1 136 ? 27.98183  12.86745  0.50065   1.000 79.52583  ? 132 SER H HB2  1 
ATOM   1995 H HB3  . SER A 1 136 ? 29.08718  12.61683  1.61457   1.000 79.52583  ? 132 SER H HB3  1 
ATOM   1996 H HG   . SER A 1 136 ? 28.38453  14.49588  2.54586   1.000 69.97506  ? 132 SER H HG   1 
ATOM   1997 N N    . GLY A 1 137 ? 31.82652  15.05008  0.56104   1.000 62.66929  ? 133 GLY H N    1 
ATOM   1998 C CA   . GLY A 1 137 ? 32.94813  15.59696  1.30656   1.000 54.17860  ? 133 GLY H CA   1 
ATOM   1999 C C    . GLY A 1 137 ? 33.59318  14.54850  2.19002   1.000 57.55920  ? 133 GLY H C    1 
ATOM   2000 O O    . GLY A 1 137 ? 34.06996  13.51083  1.71491   1.000 52.50830  ? 133 GLY H O    1 
ATOM   2001 H H    . GLY A 1 137 ? 31.91309  15.09345  -0.29349  1.000 75.20998  ? 133 GLY H H    1 
ATOM   2002 H HA2  . GLY A 1 137 ? 33.61589  15.93327  0.68858   1.000 65.02115  ? 133 GLY H HA2  1 
ATOM   2003 H HA3  . GLY A 1 137 ? 32.64079  16.32646  1.86716   1.000 65.02115  ? 133 GLY H HA3  1 
ATOM   2004 N N    . GLY A 1 138 ? 33.60848  14.81508  3.49600   1.000 50.58663  ? 134 GLY H N    1 
ATOM   2005 C CA   . GLY A 1 138 ? 34.26271  13.97117  4.47167   1.000 47.25986  ? 134 GLY H CA   1 
ATOM   2006 C C    . GLY A 1 138 ? 33.43458  12.83847  5.03396   1.000 41.41670  ? 134 GLY H C    1 
ATOM   2007 O O    . GLY A 1 138 ? 33.92633  12.09772  5.89011   1.000 37.16253  ? 134 GLY H O    1 
ATOM   2008 H H    . GLY A 1 138 ? 33.23151  15.50470  3.84517   1.000 60.71079  ? 134 GLY H H    1 
ATOM   2009 H HA2  . GLY A 1 138 ? 35.04831  13.57954  4.05894   1.000 56.71866  ? 134 GLY H HA2  1 
ATOM   2010 H HA3  . GLY A 1 138 ? 34.54094  14.52556  5.21741   1.000 56.71866  ? 134 GLY H HA3  1 
ATOM   2011 N N    . THR A 1 139 ? 32.19149  12.67734  4.58822   1.000 43.52128  ? 135 THR H N    1 
ATOM   2012 C CA   . THR A 1 139 ? 31.32173  11.59840  5.03509   1.000 41.95266  ? 135 THR H CA   1 
ATOM   2013 C C    . THR A 1 139 ? 30.89751  10.75751  3.83943   1.000 41.43920  ? 135 THR H C    1 
ATOM   2014 O O    . THR A 1 139 ? 30.65960  11.28800  2.75006   1.000 42.07324  ? 135 THR H O    1 
ATOM   2015 C CB   . THR A 1 139 ? 30.08288  12.14570  5.74323   1.000 41.67905  ? 135 THR H CB   1 
ATOM   2016 O OG1  . THR A 1 139 ? 30.48014  13.12147  6.71404   1.000 51.52813  ? 135 THR H OG1  1 
ATOM   2017 C CG2  . THR A 1 139 ? 29.32759  11.02536  6.43638   1.000 42.54756  ? 135 THR H CG2  1 
ATOM   2018 H H    . THR A 1 139 ? 31.82144  13.19599  4.01058   1.000 52.23237  ? 135 THR H H    1 
ATOM   2019 H HA   . THR A 1 139 ? 31.80363  11.03056  5.65658   1.000 50.35002  ? 135 THR H HA   1 
ATOM   2020 H HB   . THR A 1 139 ? 29.49171  12.55643  5.09306   1.000 50.02170  ? 135 THR H HB   1 
ATOM   2021 H HG1  . THR A 1 139 ? 29.80259  13.44110  7.09399   1.000 61.84059  ? 135 THR H HG1  1 
ATOM   2022 H HG21 . THR A 1 139 ? 28.57578  11.38817  6.93040   1.000 51.06391  ? 135 THR H HG21 1 
ATOM   2023 H HG22 . THR A 1 139 ? 28.99693  10.39243  5.77990   1.000 51.06391  ? 135 THR H HG22 1 
ATOM   2024 H HG23 . THR A 1 139 ? 29.91503  10.56121  7.05312   1.000 51.06391  ? 135 THR H HG23 1 
ATOM   2025 N N    . ALA A 1 140 ? 30.80775  9.44529   4.04376   1.000 34.13964  ? 136 ALA H N    1 
ATOM   2026 C CA   . ALA A 1 140 ? 30.35180  8.52319   3.01563   1.000 31.57052  ? 136 ALA H CA   1 
ATOM   2027 C C    . ALA A 1 140 ? 29.29971  7.60697   3.61859   1.000 28.59502  ? 136 ALA H C    1 
ATOM   2028 O O    . ALA A 1 140 ? 29.37918  7.25281   4.79476   1.000 29.01972  ? 136 ALA H O    1 
ATOM   2029 C CB   . ALA A 1 140 ? 31.51078  7.70079   2.44858   1.000 28.87429  ? 136 ALA H CB   1 
ATOM   2030 H H    . ALA A 1 140 ? 31.01023  9.06090   4.78595   1.000 40.97440  ? 136 ALA H H    1 
ATOM   2031 H HA   . ALA A 1 140 ? 29.95231  9.01262   2.27959   1.000 37.89146  ? 136 ALA H HA   1 
ATOM   2032 H HB1  . ALA A 1 140 ? 31.16812  7.09812   1.77015   1.000 34.65599  ? 136 ALA H HB1  1 
ATOM   2033 H HB2  . ALA A 1 140 ? 32.16329  8.30254   2.05739   1.000 34.65599  ? 136 ALA H HB2  1 
ATOM   2034 H HB3  . ALA A 1 140 ? 31.91856  7.19250   3.16709   1.000 34.65599  ? 136 ALA H HB3  1 
ATOM   2035 N N    . ALA A 1 141 ? 28.30570  7.23801   2.82532   1.000 25.60449  ? 137 ALA H N    1 
ATOM   2036 C CA   . ALA A 1 141 ? 27.28541  6.29725   3.26160   1.000 26.02346  ? 137 ALA H CA   1 
ATOM   2037 C C    . ALA A 1 141 ? 27.45708  4.99286   2.50106   1.000 20.10360  ? 137 ALA H C    1 
ATOM   2038 O O    . ALA A 1 141 ? 27.78013  4.99578   1.31016   1.000 21.48355  ? 137 ALA H O    1 
ATOM   2039 C CB   . ALA A 1 141 ? 25.88082  6.85714   3.04676   1.000 21.72372  ? 137 ALA H CB   1 
ATOM   2040 H H    . ALA A 1 141 ? 28.19959  7.52224   2.02061   1.000 30.73222  ? 137 ALA H H    1 
ATOM   2041 H HA   . ALA A 1 141 ? 27.38338  6.11944   4.21011   1.000 31.23499  ? 137 ALA H HA   1 
ATOM   2042 H HB1  . ALA A 1 141 ? 25.23061  6.20093   3.34262   1.000 26.07530  ? 137 ALA H HB1  1 
ATOM   2043 H HB2  . ALA A 1 141 ? 25.78425  7.67375   3.56127   1.000 26.07530  ? 137 ALA H HB2  1 
ATOM   2044 H HB3  . ALA A 1 141 ? 25.75627  7.04404   2.10312   1.000 26.07530  ? 137 ALA H HB3  1 
ATOM   2045 N N    . LEU A 1 142 ? 27.27482  3.88089   3.20376   1.000 20.98386  ? 138 LEU H N    1 
ATOM   2046 C CA   . LEU A 1 142 ? 27.31827  2.56547   2.58365   1.000 22.02169  ? 138 LEU H CA   1 
ATOM   2047 C C    . LEU A 1 142 ? 26.28742  1.68951   3.27752   1.000 21.33228  ? 138 LEU H C    1 
ATOM   2048 O O    . LEU A 1 142 ? 25.68679  2.08500   4.27688   1.000 18.02916  ? 138 LEU H O    1 
ATOM   2049 C CB   . LEU A 1 142 ? 28.72548  1.95973   2.64964   1.000 21.04143  ? 138 LEU H CB   1 
ATOM   2050 C CG   . LEU A 1 142 ? 29.38237  1.79256   4.02173   1.000 23.57433  ? 138 LEU H CG   1 
ATOM   2051 C CD1  . LEU A 1 142 ? 29.10388  0.41535   4.59081   1.000 26.17993  ? 138 LEU H CD1  1 
ATOM   2052 C CD2  . LEU A 1 142 ? 30.88226  2.03937   3.92497   1.000 35.56388  ? 138 LEU H CD2  1 
ATOM   2053 H H    . LEU A 1 142 ? 27.12288  3.86364   4.05006   1.000 25.18747  ? 138 LEU H H    1 
ATOM   2054 H HA   . LEU A 1 142 ? 27.08061  2.62356   1.64501   1.000 26.43286  ? 138 LEU H HA   1 
ATOM   2055 H HB2  . LEU A 1 142 ? 28.68251  1.07524   2.25374   1.000 25.25655  ? 138 LEU H HB2  1 
ATOM   2056 H HB3  . LEU A 1 142 ? 29.31382  2.52823   2.12852   1.000 25.25655  ? 138 LEU H HB3  1 
ATOM   2057 H HG   . LEU A 1 142 ? 29.00506  2.44577   4.63152   1.000 28.29603  ? 138 LEU H HG   1 
ATOM   2058 H HD11 . LEU A 1 142 ? 29.55967  0.32752   5.44254   1.000 31.42275  ? 138 LEU H HD11 1 
ATOM   2059 H HD12 . LEU A 1 142 ? 28.14741  0.31261   4.71535   1.000 31.42275  ? 138 LEU H HD12 1 
ATOM   2060 H HD13 . LEU A 1 142 ? 29.43052  -0.25476  3.97020   1.000 31.42275  ? 138 LEU H HD13 1 
ATOM   2061 H HD21 . LEU A 1 142 ? 31.28243  1.89833   4.79725   1.000 42.68349  ? 138 LEU H HD21 1 
ATOM   2062 H HD22 . LEU A 1 142 ? 31.26330  1.42075   3.28230   1.000 42.68349  ? 138 LEU H HD22 1 
ATOM   2063 H HD23 . LEU A 1 142 ? 31.03400  2.95255   3.63518   1.000 42.68349  ? 138 LEU H HD23 1 
ATOM   2064 N N    . GLY A 1 143 ? 26.04610  0.50645   2.72822   1.000 18.50384  ? 139 GLY H N    1 
ATOM   2065 C CA   . GLY A 1 143 ? 25.04194  -0.34706  3.33521   1.000 19.29596  ? 139 GLY H CA   1 
ATOM   2066 C C    . GLY A 1 143 ? 24.91430  -1.69469  2.65962   1.000 17.53909  ? 139 GLY H C    1 
ATOM   2067 O O    . GLY A 1 143 ? 25.71417  -2.07508  1.80402   1.000 17.82375  ? 139 GLY H O    1 
ATOM   2068 H H    . GLY A 1 143 ? 26.43593  0.18820   2.03083   1.000 22.21144  ? 139 GLY H H    1 
ATOM   2069 H HA2  . GLY A 1 143 ? 25.27225  -0.49705  4.26545   1.000 23.16198  ? 139 GLY H HA2  1 
ATOM   2070 H HA3  . GLY A 1 143 ? 24.17972  0.09509   3.29067   1.000 23.16198  ? 139 GLY H HA3  1 
ATOM   2071 N N    . CYS A 1 144 ? 23.87652  -2.40821  3.09158   1.000 17.15182  ? 140 CYS H N    1 
ATOM   2072 C CA   . CYS A 1 144 ? 23.47938  -3.70534  2.57004   1.000 18.80642  ? 140 CYS H CA   1 
ATOM   2073 C C    . CYS A 1 144 ? 21.97865  -3.70713  2.32654   1.000 21.53235  ? 140 CYS H C    1 
ATOM   2074 O O    . CYS A 1 144 ? 21.19528  -3.27087  3.18354   1.000 17.15427  ? 140 CYS H O    1 
ATOM   2075 C CB   . CYS A 1 144 ? 23.82820  -4.84601  3.53533   1.000 24.85858  ? 140 CYS H CB   1 
ATOM   2076 S SG   . CYS A 1 144 ? 25.56401  -5.30531  3.54501   1.000 50.37220  ? 140 CYS H SG   1 
ATOM   2077 H H    . CYS A 1 144 ? 23.35843  -2.14236  3.72443   1.000 20.58902  ? 140 CYS H H    1 
ATOM   2078 H HA   . CYS A 1 144 ? 23.94433  -3.85497  1.73199   1.000 22.57454  ? 140 CYS H HA   1 
ATOM   2079 H HB2  . CYS A 1 144 ? 23.59204  -4.57238  4.43547   1.000 29.83713  ? 140 CYS H HB2  1 
ATOM   2080 H HB3  . CYS A 1 144 ? 23.31821  -5.63154  3.28282   1.000 29.83713  ? 140 CYS H HB3  1 
ATOM   2081 N N    . LEU A 1 145 ? 21.59341  -4.20128  1.16064   1.000 16.90254  ? 141 LEU H N    1 
ATOM   2082 C CA   . LEU A 1 145 ? 20.21190  -4.48657  0.81888   1.000 18.09272  ? 141 LEU H CA   1 
ATOM   2083 C C    . LEU A 1 145 ? 19.97409  -5.97014  1.06325   1.000 17.52141  ? 141 LEU H C    1 
ATOM   2084 O O    . LEU A 1 145 ? 20.63510  -6.81455  0.45314   1.000 19.13094  ? 141 LEU H O    1 
ATOM   2085 C CB   . LEU A 1 145 ? 19.93750  -4.11251  -0.63529  1.000 18.88276  ? 141 LEU H CB   1 
ATOM   2086 C CG   . LEU A 1 145 ? 18.54794  -4.39491  -1.19358  1.000 18.06675  ? 141 LEU H CG   1 
ATOM   2087 C CD1  . LEU A 1 145 ? 17.48203  -3.61197  -0.43769  1.000 25.31627  ? 141 LEU H CD1  1 
ATOM   2088 C CD2  . LEU A 1 145 ? 18.53622  -4.05113  -2.68069  1.000 22.06360  ? 141 LEU H CD2  1 
ATOM   2089 H H    . LEU A 1 145 ? 22.13945  -4.38777  0.52294   1.000 20.28988  ? 141 LEU H H    1 
ATOM   2090 H HA   . LEU A 1 145 ? 19.60308  -3.97657  1.37579   1.000 21.71810  ? 141 LEU H HA   1 
ATOM   2091 H HB2  . LEU A 1 145 ? 20.08682  -3.15853  -0.72771  1.000 22.66614  ? 141 LEU H HB2  1 
ATOM   2092 H HB3  . LEU A 1 145 ? 20.56560  -4.60183  -1.18932  1.000 22.66614  ? 141 LEU H HB3  1 
ATOM   2093 H HG   . LEU A 1 145 ? 18.33128  -5.33404  -1.08412  1.000 21.68693  ? 141 LEU H HG   1 
ATOM   2094 H HD11 . LEU A 1 145 ? 16.61855  -3.77745  -0.84748  1.000 30.38636  ? 141 LEU H HD11 1 
ATOM   2095 H HD12 . LEU A 1 145 ? 17.47101  -3.90516  0.48688   1.000 30.38636  ? 141 LEU H HD12 1 
ATOM   2096 H HD13 . LEU A 1 145 ? 17.69359  -2.66638  -0.48234  1.000 30.38636  ? 141 LEU H HD13 1 
ATOM   2097 H HD21 . LEU A 1 145 ? 17.65330  -4.23156  -3.03958  1.000 26.48315  ? 141 LEU H HD21 1 
ATOM   2098 H HD22 . LEU A 1 145 ? 18.75180  -3.11165  -2.78935  1.000 26.48315  ? 141 LEU H HD22 1 
ATOM   2099 H HD23 . LEU A 1 145 ? 19.19628  -4.59680  -3.13618  1.000 26.48315  ? 141 LEU H HD23 1 
ATOM   2100 N N    . VAL A 1 146 ? 19.05340  -6.27640  1.96863   1.000 15.20680  ? 142 VAL H N    1 
ATOM   2101 C CA   . VAL A 1 146 ? 18.66878  -7.63339  2.33297   1.000 19.13500  ? 142 VAL H CA   1 
ATOM   2102 C C    . VAL A 1 146 ? 17.29954  -7.87445  1.71614   1.000 20.71058  ? 142 VAL H C    1 
ATOM   2103 O O    . VAL A 1 146 ? 16.29725  -7.32666  2.18744   1.000 22.24786  ? 142 VAL H O    1 
ATOM   2104 C CB   . VAL A 1 146 ? 18.62000  -7.81161  3.85590   1.000 15.77882  ? 142 VAL H CB   1 
ATOM   2105 C CG1  . VAL A 1 146 ? 18.40987  -9.27485  4.22318   1.000 17.43414  ? 142 VAL H CG1  1 
ATOM   2106 C CG2  . VAL A 1 146 ? 19.87156  -7.24686  4.48862   1.000 18.43942  ? 142 VAL H CG2  1 
ATOM   2107 H H    . VAL A 1 146 ? 18.61404  -5.68260  2.40904   1.000 18.25499  ? 142 VAL H H    1 
ATOM   2108 H HA   . VAL A 1 146 ? 19.30219  -8.26991  1.96618   1.000 22.96883  ? 142 VAL H HA   1 
ATOM   2109 H HB   . VAL A 1 146 ? 17.86389  -7.31920  4.21189   1.000 18.94141  ? 142 VAL H HB   1 
ATOM   2110 H HG11 . VAL A 1 146 ? 18.40161  -9.35988  5.18941   1.000 20.92780  ? 142 VAL H HG11 1 
ATOM   2111 H HG12 . VAL A 1 146 ? 17.56256  -9.57367  3.85758   1.000 20.92780  ? 142 VAL H HG12 1 
ATOM   2112 H HG13 . VAL A 1 146 ? 19.13473  -9.80111  3.85099   1.000 20.92780  ? 142 VAL H HG13 1 
ATOM   2113 H HG21 . VAL A 1 146 ? 19.89220  -7.49694  5.42560   1.000 22.13414  ? 142 VAL H HG21 1 
ATOM   2114 H HG22 . VAL A 1 146 ? 20.64714  -7.60915  4.03241   1.000 22.13414  ? 142 VAL H HG22 1 
ATOM   2115 H HG23 . VAL A 1 146 ? 19.85964  -6.28061  4.40434   1.000 22.13414  ? 142 VAL H HG23 1 
ATOM   2116 N N    . LYS A 1 147 ? 17.24364  -8.68621  0.66821   1.000 18.88480  ? 143 LYS H N    1 
ATOM   2117 C CA   . LYS A 1 147 ? 16.06478  -8.77617  -0.17434  1.000 22.20531  ? 143 LYS H CA   1 
ATOM   2118 C C    . LYS A 1 147 ? 15.51566  -10.19662 -0.23072  1.000 21.03227  ? 143 LYS H C    1 
ATOM   2119 O O    . LYS A 1 147 ? 16.26316  -11.18034 -0.15819  1.000 19.10049  ? 143 LYS H O    1 
ATOM   2120 C CB   . LYS A 1 147 ? 16.40174  -8.29030  -1.59633  1.000 29.30049  ? 143 LYS H CB   1 
ATOM   2121 C CG   . LYS A 1 147 ? 15.20288  -7.79232  -2.38844  1.000 36.18933  ? 143 LYS H CG   1 
ATOM   2122 C CD   . LYS A 1 147 ? 15.64822  -7.07948  -3.64482  1.000 30.36466  ? 143 LYS H CD   1 
ATOM   2123 C CE   . LYS A 1 147 ? 14.76236  -7.42651  -4.82725  1.000 39.32988  ? 143 LYS H CE   1 
ATOM   2124 N NZ   . LYS A 1 147 ? 13.43369  -6.78204  -4.74740  1.000 42.78861  ? 143 LYS H NZ   1 
ATOM   2125 H H    . LYS A 1 147 ? 17.88714  -9.20160  0.42350   1.000 22.66859  ? 143 LYS H H    1 
ATOM   2126 H HA   . LYS A 1 147 ? 15.36031  -8.22684  0.20361   1.000 26.65321  ? 143 LYS H HA   1 
ATOM   2127 H HB2  . LYS A 1 147 ? 17.03542  -7.55876  -1.53154  1.000 35.16742  ? 143 LYS H HB2  1 
ATOM   2128 H HB3  . LYS A 1 147 ? 16.79473  -9.02687  -2.09021  1.000 35.16742  ? 143 LYS H HB3  1 
ATOM   2129 H HG2  . LYS A 1 147 ? 14.64694  -8.54550  -2.64252  1.000 43.43403  ? 143 LYS H HG2  1 
ATOM   2130 H HG3  . LYS A 1 147 ? 14.69204  -7.17080  -1.84655  1.000 43.43403  ? 143 LYS H HG3  1 
ATOM   2131 H HD2  . LYS A 1 147 ? 15.60465  -6.12095  -3.50263  1.000 36.44442  ? 143 LYS H HD2  1 
ATOM   2132 H HD3  . LYS A 1 147 ? 16.55731  -7.34228  -3.85791  1.000 36.44442  ? 143 LYS H HD3  1 
ATOM   2133 H HE2  . LYS A 1 147 ? 15.19247  -7.12879  -5.64412  1.000 47.20269  ? 143 LYS H HE2  1 
ATOM   2134 H HE3  . LYS A 1 147 ? 14.62970  -8.38704  -4.85322  1.000 47.20269  ? 143 LYS H HE3  1 
ATOM   2135 H HZ1  . LYS A 1 147 ? 13.52477  -5.89675  -4.73948  1.000 51.35316  ? 143 LYS H HZ1  1 
ATOM   2136 H HZ2  . LYS A 1 147 ? 12.93952  -7.01530  -5.44988  1.000 51.35316  ? 143 LYS H HZ2  1 
ATOM   2137 H HZ3  . LYS A 1 147 ? 13.01635  -7.03613  -4.00351  1.000 51.35316  ? 143 LYS H HZ3  1 
ATOM   2138 N N    . ASP A 1 148 ? 14.18670  -10.27921 -0.36544  1.000 19.64855  ? 144 ASP H N    1 
ATOM   2139 C CA   . ASP A 1 148 ? 13.47911  -11.48770 -0.77373  1.000 22.70762  ? 144 ASP H CA   1 
ATOM   2140 C C    . ASP A 1 148 ? 13.58276  -12.61335 0.24586   1.000 21.85423  ? 144 ASP H C    1 
ATOM   2141 O O    . ASP A 1 148 ? 13.97393  -13.73256 -0.09597  1.000 24.95080  ? 144 ASP H O    1 
ATOM   2142 C CB   . ASP A 1 148 ? 13.99383  -11.94876 -2.13606  1.000 25.32897  ? 144 ASP H CB   1 
ATOM   2143 C CG   . ASP A 1 148 ? 13.58775  -11.00340 -3.25247  1.000 33.42932  ? 144 ASP H CG   1 
ATOM   2144 O OD1  . ASP A 1 148 ? 12.75811  -10.10397 -2.98754  1.000 30.82184  ? 144 ASP H OD1  1 
ATOM   2145 O OD2  . ASP A 1 148 ? 14.09639  -11.15003 -4.38600  1.000 36.32917  ? 144 ASP H OD2  1 
ATOM   2146 H H    . ASP A 1 148 ? 13.65452  -9.61967  -0.21921  1.000 23.58510  ? 144 ASP H H    1 
ATOM   2147 H HA   . ASP A 1 148 ? 12.53524  -11.27467 -0.84180  1.000 27.25598  ? 144 ASP H HA   1 
ATOM   2148 H HB2  . ASP A 1 148 ? 14.96265  -11.99058 -2.11273  1.000 30.40160  ? 144 ASP H HB2  1 
ATOM   2149 H HB3  . ASP A 1 148 ? 13.62861  -12.82524 -2.33429  1.000 30.40160  ? 144 ASP H HB3  1 
ATOM   2150 N N    . TYR A 1 149 ? 13.19494  -12.34359 1.48973   1.000 19.56934  ? 145 TYR H N    1 
ATOM   2151 C CA   . TYR A 1 149 ? 13.21583  -13.35044 2.53669   1.000 18.21642  ? 145 TYR H CA   1 
ATOM   2152 C C    . TYR A 1 149 ? 11.84066  -13.49579 3.17133   1.000 18.03637  ? 145 TYR H C    1 
ATOM   2153 O O    . TYR A 1 149 ? 10.97928  -12.61777 3.07145   1.000 17.68947  ? 145 TYR H O    1 
ATOM   2154 C CB   . TYR A 1 149 ? 14.25967  -13.02005 3.62010   1.000 19.89200  ? 145 TYR H CB   1 
ATOM   2155 C CG   . TYR A 1 149 ? 14.01002  -11.76049 4.42697   1.000 15.09763  ? 145 TYR H CG   1 
ATOM   2156 C CD1  . TYR A 1 149 ? 13.25761  -11.79287 5.59716   1.000 16.89084  ? 145 TYR H CD1  1 
ATOM   2157 C CD2  . TYR A 1 149 ? 14.56144  -10.55040 4.04201   1.000 16.06846  ? 145 TYR H CD2  1 
ATOM   2158 C CE1  . TYR A 1 149 ? 13.04106  -10.64549 6.34454   1.000 16.70618  ? 145 TYR H CE1  1 
ATOM   2159 C CE2  . TYR A 1 149 ? 14.34941  -9.40004  4.78274   1.000 17.87135  ? 145 TYR H CE2  1 
ATOM   2160 C CZ   . TYR A 1 149 ? 13.59407  -9.45779  5.93731   1.000 18.40356  ? 145 TYR H CZ   1 
ATOM   2161 O OH   . TYR A 1 149 ? 13.38151  -8.31833  6.67861   1.000 19.05860  ? 145 TYR H OH   1 
ATOM   2162 H H    . TYR A 1 149 ? 12.91296  -11.57413 1.75054   1.000 23.49005  ? 145 TYR H H    1 
ATOM   2163 H HA   . TYR A 1 149 ? 13.44976  -14.20389 2.13944   1.000 21.86654  ? 145 TYR H HA   1 
ATOM   2164 H HB2  . TYR A 1 149 ? 14.28961  -13.75972 4.24691   1.000 23.87724  ? 145 TYR H HB2  1 
ATOM   2165 H HB3  . TYR A 1 149 ? 15.12184  -12.91636 3.18788   1.000 23.87724  ? 145 TYR H HB3  1 
ATOM   2166 H HD1  . TYR A 1 149 ? 12.89323  -12.59929 5.88319   1.000 20.27585  ? 145 TYR H HD1  1 
ATOM   2167 H HD2  . TYR A 1 149 ? 15.08294  -10.50952 3.27308   1.000 19.28898  ? 145 TYR H HD2  1 
ATOM   2168 H HE1  . TYR A 1 149 ? 12.52427  -10.68066 7.11694   1.000 20.05426  ? 145 TYR H HE1  1 
ATOM   2169 H HE2  . TYR A 1 149 ? 14.71436  -8.59141  4.50374   1.000 21.45245  ? 145 TYR H HE2  1 
ATOM   2170 H HH   . TYR A 1 149 ? 12.91113  -8.49679  7.35129   1.000 22.87715  ? 145 TYR H HH   1 
ATOM   2171 N N    . PHE A 1 150 ? 11.65162  -14.62708 3.84893   1.000 14.37547  ? 146 PHE H N    1 
ATOM   2172 C CA   . PHE A 1 150 ? 10.39212  -14.88684 4.51706   1.000 16.22500  ? 146 PHE H CA   1 
ATOM   2173 C C    . PHE A 1 150 ? 10.61157  -16.01693 5.50854   1.000 16.75858  ? 146 PHE H C    1 
ATOM   2174 O O    . PHE A 1 150 ? 11.31871  -16.97813 5.17780   1.000 14.79325  ? 146 PHE H O    1 
ATOM   2175 C CB   . PHE A 1 150 ? 9.28292   -15.26893 3.52830   1.000 16.39890  ? 146 PHE H CB   1 
ATOM   2176 C CG   . PHE A 1 150 ? 7.93247   -15.39499 4.17332   1.000 19.29962  ? 146 PHE H CG   1 
ATOM   2177 C CD1  . PHE A 1 150 ? 7.10618   -14.28960 4.29606   1.000 21.74729  ? 146 PHE H CD1  1 
ATOM   2178 C CD2  . PHE A 1 150 ? 7.50056   -16.60822 4.68490   1.000 16.97481  ? 146 PHE H CD2  1 
ATOM   2179 C CE1  . PHE A 1 150 ? 5.86937   -14.38977 4.90699   1.000 23.69637  ? 146 PHE H CE1  1 
ATOM   2180 C CE2  . PHE A 1 150 ? 6.26217   -16.71276 5.29655   1.000 21.50077  ? 146 PHE H CE2  1 
ATOM   2181 C CZ   . PHE A 1 150 ? 5.44669   -15.60432 5.40328   1.000 18.81828  ? 146 PHE H CZ   1 
ATOM   2182 H H    . PHE A 1 150 ? 12.23694  -15.25162 3.93234   1.000 17.25739  ? 146 PHE H H    1 
ATOM   2183 H HA   . PHE A 1 150 ? 10.11053  -14.08941 4.99214   1.000 19.47683  ? 146 PHE H HA   1 
ATOM   2184 H HB2  . PHE A 1 150 ? 9.22365   -14.58479 2.84322   1.000 19.68552  ? 146 PHE H HB2  1 
ATOM   2185 H HB3  . PHE A 1 150 ? 9.50213   -16.12368 3.12550   1.000 19.68552  ? 146 PHE H HB3  1 
ATOM   2186 H HD1  . PHE A 1 150 ? 7.38734   -13.46817 3.96273   1.000 26.10358  ? 146 PHE H HD1  1 
ATOM   2187 H HD2  . PHE A 1 150 ? 8.04641   -17.35811 4.61704   1.000 20.37661  ? 146 PHE H HD2  1 
ATOM   2188 H HE1  . PHE A 1 150 ? 5.32451   -13.63991 4.98273   1.000 28.44248  ? 146 PHE H HE1  1 
ATOM   2189 H HE2  . PHE A 1 150 ? 5.97969   -17.53126 5.63591   1.000 25.80776  ? 146 PHE H HE2  1 
ATOM   2190 H HZ   . PHE A 1 150 ? 4.61322   -15.67678 5.80945   1.000 22.58877  ? 146 PHE H HZ   1 
ATOM   2191 N N    . PRO A 1 151 ? 10.03900  -15.93908 6.71933   1.000 17.89090  ? 147 PRO H N    1 
ATOM   2192 C CA   . PRO A 1 151 ? 9.30174   -14.80186 7.27395   1.000 15.65524  ? 147 PRO H CA   1 
ATOM   2193 C C    . PRO A 1 151 ? 10.25645  -13.82736 7.93243   1.000 17.66251  ? 147 PRO H C    1 
ATOM   2194 O O    . PRO A 1 151 ? 11.47207  -14.01075 7.83827   1.000 16.33623  ? 147 PRO H O    1 
ATOM   2195 C CB   . PRO A 1 151 ? 8.40028   -15.45503 8.31475   1.000 17.30300  ? 147 PRO H CB   1 
ATOM   2196 C CG   . PRO A 1 151 ? 9.27092   -16.53325 8.86946   1.000 19.19487  ? 147 PRO H CG   1 
ATOM   2197 C CD   . PRO A 1 151 ? 10.07198  -17.05986 7.67608   1.000 19.63258  ? 147 PRO H CD   1 
ATOM   2198 H HA   . PRO A 1 151 ? 8.75321   -14.35442 6.61077   1.000 18.79313  ? 147 PRO H HA   1 
ATOM   2199 H HB2  . PRO A 1 151 ? 8.14965   -14.81349 8.99776   1.000 20.77044  ? 147 PRO H HB2  1 
ATOM   2200 H HB3  . PRO A 1 151 ? 7.60569   -15.82009 7.89491   1.000 20.77044  ? 147 PRO H HB3  1 
ATOM   2201 H HG2  . PRO A 1 151 ? 9.86054   -16.16509 9.54600   1.000 23.04068  ? 147 PRO H HG2  1 
ATOM   2202 H HG3  . PRO A 1 151 ? 8.72211   -17.23468 9.25380   1.000 23.04068  ? 147 PRO H HG3  1 
ATOM   2203 H HD2  . PRO A 1 151 ? 10.98384  -17.26410 7.93627   1.000 23.56594  ? 147 PRO H HD2  1 
ATOM   2204 H HD3  . PRO A 1 151 ? 9.65031   -17.84766 7.29864   1.000 23.56594  ? 147 PRO H HD3  1 
ATOM   2205 N N    . GLU A 1 152 ? 9.72032   -12.82305 8.61652   1.000 17.33065  ? 148 GLU H N    1 
ATOM   2206 C CA   . GLU A 1 152 ? 10.54474  -12.02351 9.49984   1.000 17.95673  ? 148 GLU H CA   1 
ATOM   2207 C C    . GLU A 1 152 ? 10.98589  -12.87341 10.68937  1.000 15.03901  ? 148 GLU H C    1 
ATOM   2208 O O    . GLU A 1 152 ? 10.38423  -13.90675 10.98029  1.000 19.21906  ? 148 GLU H O    1 
ATOM   2209 C CB   . GLU A 1 152 ? 9.78365   -10.79085 9.98124   1.000 21.58430  ? 148 GLU H CB   1 
ATOM   2210 C CG   . GLU A 1 152 ? 9.41222   -9.81458  8.86645   1.000 25.89697  ? 148 GLU H CG   1 
ATOM   2211 C CD   . GLU A 1 152 ? 9.29609   -8.37909  9.35506   1.000 35.82290  ? 148 GLU H CD   1 
ATOM   2212 O OE1  . GLU A 1 152 ? 10.32895  -7.79907  9.76075   1.000 36.25007  ? 148 GLU H OE1  1 
ATOM   2213 O OE2  . GLU A 1 152 ? 8.17319   -7.83128  9.33914   1.000 40.75733  ? 148 GLU H OE2  1 
ATOM   2214 H H    . GLU A 1 152 ? 8.89297   -12.59055 8.58453   1.000 20.80361  ? 148 GLU H H    1 
ATOM   2215 H HA   . GLU A 1 152 ? 11.33226  -11.71117 9.02744   1.000 21.55491  ? 148 GLU H HA   1 
ATOM   2216 H HB2  . GLU A 1 152 ? 8.96112   -11.07991 10.40643  1.000 25.90799  ? 148 GLU H HB2  1 
ATOM   2217 H HB3  . GLU A 1 152 ? 10.33691  -10.31353 10.61918  1.000 25.90799  ? 148 GLU H HB3  1 
ATOM   2218 H HG2  . GLU A 1 152 ? 10.09713  -9.84320  8.18017   1.000 31.08320  ? 148 GLU H HG2  1 
ATOM   2219 H HG3  . GLU A 1 152 ? 8.55597   -10.07390 8.49164   1.000 31.08320  ? 148 GLU H HG3  1 
ATOM   2220 N N    . PRO A 1 153 ? 12.04294  -12.45906 11.39989  1.000 16.39468  ? 149 PRO H N    1 
ATOM   2221 C CA   . PRO A 1 153 ? 12.86569  -11.27961 11.15290  1.000 18.15488  ? 149 PRO H CA   1 
ATOM   2222 C C    . PRO A 1 153 ? 14.25309  -11.64119 10.65095  1.000 18.39391  ? 149 PRO H C    1 
ATOM   2223 O O    . PRO A 1 153 ? 14.65840  -12.79594 10.73323  1.000 17.28651  ? 149 PRO H O    1 
ATOM   2224 C CB   . PRO A 1 153 ? 12.95784  -10.65198 12.53880  1.000 18.51620  ? 149 PRO H CB   1 
ATOM   2225 C CG   . PRO A 1 153 ? 13.05835  -11.86882 13.44568  1.000 19.91292  ? 149 PRO H CG   1 
ATOM   2226 C CD   . PRO A 1 153 ? 12.33014  -13.01647 12.73771  1.000 19.74686  ? 149 PRO H CD   1 
ATOM   2227 H HA   . PRO A 1 153 ? 12.43813  -10.67164 10.52963  1.000 21.79269  ? 149 PRO H HA   1 
ATOM   2228 H HB2  . PRO A 1 153 ? 13.74646  -10.09127 12.60652  1.000 22.22628  ? 149 PRO H HB2  1 
ATOM   2229 H HB3  . PRO A 1 153 ? 12.16256  -10.13041 12.72955  1.000 22.22628  ? 149 PRO H HB3  1 
ATOM   2230 H HG2  . PRO A 1 153 ? 13.99218  -12.09270 13.58261  1.000 23.90234  ? 149 PRO H HG2  1 
ATOM   2231 H HG3  . PRO A 1 153 ? 12.63601  -11.67262 14.29658  1.000 23.90234  ? 149 PRO H HG3  1 
ATOM   2232 H HD2  . PRO A 1 153 ? 12.90002  -13.79859 12.67121  1.000 23.70306  ? 149 PRO H HD2  1 
ATOM   2233 H HD3  . PRO A 1 153 ? 11.50879  -13.24289 13.20141  1.000 23.70306  ? 149 PRO H HD3  1 
ATOM   2234 N N    . VAL A 1 154 ? 14.96801  -10.65431 10.13178  1.000 19.19807  ? 150 VAL H N    1 
ATOM   2235 C CA   . VAL A 1 154 ? 16.41289  -10.73877 9.98952   1.000 20.13643  ? 150 VAL H CA   1 
ATOM   2236 C C    . VAL A 1 154 ? 17.00337  -9.75870  10.98815  1.000 16.35549  ? 150 VAL H C    1 
ATOM   2237 O O    . VAL A 1 154 ? 16.36975  -8.76431  11.36409  1.000 18.47462  ? 150 VAL H O    1 
ATOM   2238 C CB   . VAL A 1 154 ? 16.93286  -10.42736 8.56992   1.000 22.99282  ? 150 VAL H CB   1 
ATOM   2239 C CG1  . VAL A 1 154 ? 16.30191  -11.34361 7.54605   1.000 17.29958  ? 150 VAL H CG1  1 
ATOM   2240 C CG2  . VAL A 1 154 ? 16.69641  -8.97370  8.22279   1.000 23.50257  ? 150 VAL H CG2  1 
ATOM   2241 H H    . VAL A 1 154 ? 14.63335  -9.91382  9.85022   1.000 23.04452  ? 150 VAL H H    1 
ATOM   2242 H HA   . VAL A 1 154 ? 16.68943  -11.64799 10.18377  1.000 24.17055  ? 150 VAL H HA   1 
ATOM   2243 H HB   . VAL A 1 154 ? 17.88955  -10.58622 8.54963   1.000 27.59821  ? 150 VAL H HB   1 
ATOM   2244 H HG11 . VAL A 1 154 ? 16.56311  -11.05262 6.65835   1.000 20.76633  ? 150 VAL H HG11 1 
ATOM   2245 H HG12 . VAL A 1 154 ? 16.61017  -12.25017 7.70103   1.000 20.76633  ? 150 VAL H HG12 1 
ATOM   2246 H HG13 . VAL A 1 154 ? 15.33709  -11.30217 7.63720   1.000 20.76633  ? 150 VAL H HG13 1 
ATOM   2247 H HG21 . VAL A 1 154 ? 16.78242  -8.86011  7.26331   1.000 28.20991  ? 150 VAL H HG21 1 
ATOM   2248 H HG22 . VAL A 1 154 ? 15.80367  -8.72234  8.50693   1.000 28.20991  ? 150 VAL H HG22 1 
ATOM   2249 H HG23 . VAL A 1 154 ? 17.35510  -8.42847  8.68078   1.000 28.20991  ? 150 VAL H HG23 1 
ATOM   2250 N N    . THR A 1 155 ? 18.21006  -10.06019 11.44020  1.000 18.98861  ? 151 THR H N    1 
ATOM   2251 C CA   . THR A 1 155 ? 19.00455  -9.12753  12.21974  1.000 22.83679  ? 151 THR H CA   1 
ATOM   2252 C C    . THR A 1 155 ? 20.22012  -8.74274  11.39543  1.000 20.06757  ? 151 THR H C    1 
ATOM   2253 O O    . THR A 1 155 ? 20.73921  -9.55059  10.61941  1.000 20.01986  ? 151 THR H O    1 
ATOM   2254 C CB   . THR A 1 155 ? 19.45122  -9.73579  13.55009  1.000 20.43238  ? 151 THR H CB   1 
ATOM   2255 O OG1  . THR A 1 155 ? 20.22696  -10.90803 13.29134  1.000 21.19709  ? 151 THR H OG1  1 
ATOM   2256 C CG2  . THR A 1 155 ? 18.24606  -10.10292 14.40428  1.000 28.22804  ? 151 THR H CG2  1 
ATOM   2257 H H    . THR A 1 155 ? 18.59799  -10.81571 11.30493  1.000 22.79316  ? 151 THR H H    1 
ATOM   2258 H HA   . THR A 1 155 ? 18.48467  -8.33628  12.43082  1.000 27.41099  ? 151 THR H HA   1 
ATOM   2259 H HB   . THR A 1 155 ? 19.98408  -9.09213  14.04271  1.000 24.52569  ? 151 THR H HB   1 
ATOM   2260 H HG1  . THR A 1 155 ? 20.94606  -10.69852 12.91109  1.000 25.44334  ? 151 THR H HG1  1 
ATOM   2261 H HG21 . THR A 1 155 ? 18.54000  -10.44792 15.26188  1.000 33.88048  ? 151 THR H HG21 1 
ATOM   2262 H HG22 . THR A 1 155 ? 17.69362  -9.31955  14.55272  1.000 33.88048  ? 151 THR H HG22 1 
ATOM   2263 H HG23 . THR A 1 155 ? 17.71655  -10.78135 13.95679  1.000 33.88048  ? 151 THR H HG23 1 
ATOM   2264 N N    . VAL A 1 156 ? 20.65792  -7.50046  11.55620  1.000 16.34613  ? 152 VAL H N    1 
ATOM   2265 C CA   . VAL A 1 156 ? 21.80586  -6.97718  10.83463  1.000 16.78825  ? 152 VAL H CA   1 
ATOM   2266 C C    . VAL A 1 156 ? 22.74237  -6.32684  11.84099  1.000 20.07033  ? 152 VAL H C    1 
ATOM   2267 O O    . VAL A 1 156 ? 22.31153  -5.49964  12.65101  1.000 19.79860  ? 152 VAL H O    1 
ATOM   2268 C CB   . VAL A 1 156 ? 21.39387  -5.96068  9.75081   1.000 18.67697  ? 152 VAL H CB   1 
ATOM   2269 C CG1  . VAL A 1 156 ? 22.61672  -5.53670  8.93554   1.000 20.29869  ? 152 VAL H CG1  1 
ATOM   2270 C CG2  . VAL A 1 156 ? 20.29908  -6.53884  8.85884   1.000 19.36292  ? 152 VAL H CG2  1 
ATOM   2271 H H    . VAL A 1 156 ? 20.29710  -6.93079  12.08996  1.000 19.62219  ? 152 VAL H H    1 
ATOM   2272 H HA   . VAL A 1 156 ? 22.27246  -7.70974  10.40272  1.000 20.15273  ? 152 VAL H HA   1 
ATOM   2273 H HB   . VAL A 1 156 ? 21.03033  -5.16787  10.17530  1.000 22.41919  ? 152 VAL H HB   1 
ATOM   2274 H HG11 . VAL A 1 156 ? 22.32356  -5.00102  8.18188   1.000 24.36527  ? 152 VAL H HG11 1 
ATOM   2275 H HG12 . VAL A 1 156 ? 23.20834  -5.01615  9.50114   1.000 24.36527  ? 152 VAL H HG12 1 
ATOM   2276 H HG13 . VAL A 1 156 ? 23.07564  -6.33035  8.61866   1.000 24.36527  ? 152 VAL H HG13 1 
ATOM   2277 H HG21 . VAL A 1 156 ? 20.13171  -5.92536  8.12637   1.000 23.24234  ? 152 VAL H HG21 1 
ATOM   2278 H HG22 . VAL A 1 156 ? 20.59382  -7.39545  8.51208   1.000 23.24234  ? 152 VAL H HG22 1 
ATOM   2279 H HG23 . VAL A 1 156 ? 19.49199  -6.65468  9.38429   1.000 23.24234  ? 152 VAL H HG23 1 
ATOM   2280 N N    . SER A 1 157 ? 24.00769  -6.71986  11.80568  1.000 19.19419  ? 153 SER H N    1 
ATOM   2281 C CA   . SER A 1 157 ? 25.07092  -6.03666  12.52749  1.000 18.40383  ? 153 SER H CA   1 
ATOM   2282 C C    . SER A 1 157 ? 26.14725  -5.65038  11.52238  1.000 19.41752  ? 153 SER H C    1 
ATOM   2283 O O    . SER A 1 157 ? 26.12471  -6.07838  10.36794  1.000 18.94723  ? 153 SER H O    1 
ATOM   2284 C CB   . SER A 1 157 ? 25.64604  -6.91197  13.64997  1.000 25.94457  ? 153 SER H CB   1 
ATOM   2285 O OG   . SER A 1 157 ? 26.44249  -7.97005  13.14190  1.000 30.69630  ? 153 SER H OG   1 
ATOM   2286 H H    . SER A 1 157 ? 24.28292  -7.40000  11.35705  1.000 23.03986  ? 153 SER H H    1 
ATOM   2287 H HA   . SER A 1 157 ? 24.73033  -5.23329  12.95115  1.000 22.09144  ? 153 SER H HA   1 
ATOM   2288 H HB2  . SER A 1 157 ? 26.19532  -6.35794  14.22638  1.000 31.14032  ? 153 SER H HB2  1 
ATOM   2289 H HB3  . SER A 1 157 ? 24.91097  -7.29122  14.15667  1.000 31.14032  ? 153 SER H HB3  1 
ATOM   2290 H HG   . SER A 1 157 ? 27.14703  -7.66235  12.80345  1.000 36.84239  ? 153 SER H HG   1 
ATOM   2291 N N    . TRP A 1 158 ? 27.08145  -4.80653  11.95110  1.000 20.63017  ? 154 TRP H N    1 
ATOM   2292 C CA   . TRP A 1 158 ? 28.20211  -4.39472  11.11568  1.000 20.24136  ? 154 TRP H CA   1 
ATOM   2293 C C    . TRP A 1 158 ? 29.50035  -4.72104  11.83576  1.000 20.87677  ? 154 TRP H C    1 
ATOM   2294 O O    . TRP A 1 158 ? 29.62971  -4.46778  13.03861  1.000 24.56186  ? 154 TRP H O    1 
ATOM   2295 C CB   . TRP A 1 158 ? 28.13555  -2.90221  10.78119  1.000 21.85531  ? 154 TRP H CB   1 
ATOM   2296 C CG   . TRP A 1 158 ? 27.07348  -2.57638  9.77046   1.000 18.31065  ? 154 TRP H CG   1 
ATOM   2297 C CD1  . TRP A 1 158 ? 25.76957  -2.28113  10.01952  1.000 18.17605  ? 154 TRP H CD1  1 
ATOM   2298 C CD2  . TRP A 1 158 ? 27.23287  -2.52510  8.34881   1.000 19.26771  ? 154 TRP H CD2  1 
ATOM   2299 N NE1  . TRP A 1 158 ? 25.10018  -2.05173  8.84042   1.000 19.65348  ? 154 TRP H NE1  1 
ATOM   2300 C CE2  . TRP A 1 158 ? 25.98106  -2.18972  7.80013   1.000 18.52172  ? 154 TRP H CE2  1 
ATOM   2301 C CE3  . TRP A 1 158 ? 28.31386  -2.72754  7.48759   1.000 17.34754  ? 154 TRP H CE3  1 
ATOM   2302 C CZ2  . TRP A 1 158 ? 25.77946  -2.05598  6.43245   1.000 20.61127  ? 154 TRP H CZ2  1 
ATOM   2303 C CZ3  . TRP A 1 158 ? 28.11588  -2.58823  6.13314   1.000 19.84505  ? 154 TRP H CZ3  1 
ATOM   2304 C CH2  . TRP A 1 158 ? 26.85572  -2.25892  5.61548   1.000 20.99977  ? 154 TRP H CH2  1 
ATOM   2305 H H    . TRP A 1 158 ? 27.08627  -4.45415  12.73558  1.000 24.76304  ? 154 TRP H H    1 
ATOM   2306 H HA   . TRP A 1 158 ? 28.18049  -4.88615  10.27966  1.000 24.29647  ? 154 TRP H HA   1 
ATOM   2307 H HB2  . TRP A 1 158 ? 27.94035  -2.40598  11.59147  1.000 26.23321  ? 154 TRP H HB2  1 
ATOM   2308 H HB3  . TRP A 1 158 ? 28.99042  -2.62205  10.41840  1.000 26.23321  ? 154 TRP H HB3  1 
ATOM   2309 H HD1  . TRP A 1 158 ? 25.38575  -2.24024  10.86564  1.000 21.81809  ? 154 TRP H HD1  1 
ATOM   2310 H HE1  . TRP A 1 158 ? 24.26630  -1.85427  8.76795   1.000 23.59102  ? 154 TRP H HE1  1 
ATOM   2311 H HE3  . TRP A 1 158 ? 29.15153  -2.95223  7.82335   1.000 20.82388  ? 154 TRP H HE3  1 
ATOM   2312 H HZ2  . TRP A 1 158 ? 24.94456  -1.83687  6.08627   1.000 24.74036  ? 154 TRP H HZ2  1 
ATOM   2313 H HZ3  . TRP A 1 158 ? 28.83029  -2.71471  5.55132   1.000 23.82090  ? 154 TRP H HZ3  1 
ATOM   2314 H HH2  . TRP A 1 158 ? 26.74971  -2.17670  4.69521   1.000 25.20656  ? 154 TRP H HH2  1 
ATOM   2315 N N    . ASN A 1 159 ? 30.44604  -5.29736  11.09803  1.000 20.42217  ? 155 ASN H N    1 
ATOM   2316 C CA   . ASN A 1 159 ? 31.74156  -5.69677  11.64986  1.000 23.86131  ? 155 ASN H CA   1 
ATOM   2317 C C    . ASN A 1 159 ? 31.56687  -6.48419  12.94145  1.000 22.46425  ? 155 ASN H C    1 
ATOM   2318 O O    . ASN A 1 159 ? 32.25408  -6.25217  13.93937  1.000 25.49121  ? 155 ASN H O    1 
ATOM   2319 C CB   . ASN A 1 159 ? 32.63489  -4.48211  11.86117  1.000 19.96217  ? 155 ASN H CB   1 
ATOM   2320 C CG   . ASN A 1 159 ? 33.01975  -3.83485  10.56435  1.000 24.29720  ? 155 ASN H CG   1 
ATOM   2321 O OD1  . ASN A 1 159 ? 32.85511  -4.42667  9.49411   1.000 25.95414  ? 155 ASN H OD1  1 
ATOM   2322 N ND2  . ASN A 1 159 ? 33.53428  -2.61299  10.63939  1.000 25.27631  ? 155 ASN H ND2  1 
ATOM   2323 H H    . ASN A 1 159 ? 30.36155  -5.47153  10.26010  1.000 24.51344  ? 155 ASN H H    1 
ATOM   2324 H HA   . ASN A 1 159 ? 32.18142  -6.28265  11.01412  1.000 28.64041  ? 155 ASN H HA   1 
ATOM   2325 H HB2  . ASN A 1 159 ? 32.16132  -3.82742  12.39784  1.000 23.96144  ? 155 ASN H HB2  1 
ATOM   2326 H HB3  . ASN A 1 159 ? 33.44664  -4.75825  12.31470  1.000 23.96144  ? 155 ASN H HB3  1 
ATOM   2327 H HD21 . ASN A 1 159 ? 33.77016  -2.20096  9.92232   1.000 30.33840  ? 155 ASN H HD21 1 
ATOM   2328 H HD22 . ASN A 1 159 ? 33.63163  -2.23369  11.40507  1.000 30.33840  ? 155 ASN H HD22 1 
ATOM   2329 N N    . SER A 1 160 ? 30.62164  -7.42266  12.91553  1.000 20.48845  ? 156 SER H N    1 
ATOM   2330 C CA   . SER A 1 160 ? 30.38877  -8.35214  14.01640  1.000 22.67139  ? 156 SER H CA   1 
ATOM   2331 C C    . SER A 1 160 ? 30.06066  -7.62063  15.31040  1.000 27.26167  ? 156 SER H C    1 
ATOM   2332 O O    . SER A 1 160 ? 30.33838  -8.11700  16.40584  1.000 28.29229  ? 156 SER H O    1 
ATOM   2333 C CB   . SER A 1 160 ? 31.59192  -9.27768  14.21665  1.000 24.29246  ? 156 SER H CB   1 
ATOM   2334 O OG   . SER A 1 160 ? 31.87588  -9.99278  13.02961  1.000 25.57944  ? 156 SER H OG   1 
ATOM   2335 H H    . SER A 1 160 ? 30.08799  -7.54328  12.25199  1.000 24.59298  ? 156 SER H H    1 
ATOM   2336 H HA   . SER A 1 160 ? 29.62075  -8.90112  13.79352  1.000 27.21250  ? 156 SER H HA   1 
ATOM   2337 H HB2  . SER A 1 160 ? 32.36524  -8.74369  14.45690  1.000 29.15779  ? 156 SER H HB2  1 
ATOM   2338 H HB3  . SER A 1 160 ? 31.39115  -9.90854  14.92560  1.000 29.15779  ? 156 SER H HB3  1 
ATOM   2339 H HG   . SER A 1 160 ? 32.04960  -9.45727  12.40619  1.000 30.70216  ? 156 SER H HG   1 
ATOM   2340 N N    . GLY A 1 161 ? 29.46203  -6.43881  15.18916  1.000 26.52295  ? 157 GLY H N    1 
ATOM   2341 C CA   . GLY A 1 161 ? 29.01571  -5.67037  16.32768  1.000 24.14796  ? 157 GLY H CA   1 
ATOM   2342 C C    . GLY A 1 161 ? 29.92809  -4.52967  16.71801  1.000 24.82381  ? 157 GLY H C    1 
ATOM   2343 O O    . GLY A 1 161 ? 29.50738  -3.66193  17.49146  1.000 30.96486  ? 157 GLY H O    1 
ATOM   2344 H H    . GLY A 1 161 ? 29.30268  -6.05798  14.43472  1.000 31.83437  ? 157 GLY H H    1 
ATOM   2345 H HA2  . GLY A 1 161 ? 28.14306  -5.29680  16.12813  1.000 28.98439  ? 157 GLY H HA2  1 
ATOM   2346 H HA3  . GLY A 1 161 ? 28.93841  -6.26274  17.09189  1.000 28.98439  ? 157 GLY H HA3  1 
ATOM   2347 N N    . ALA A 1 162 ? 31.15348  -4.49483  16.19396  1.000 28.45605  ? 158 ALA H N    1 
ATOM   2348 C CA   . ALA A 1 162 ? 32.08818  -3.43541  16.54924  1.000 28.93891  ? 158 ALA H CA   1 
ATOM   2349 C C    . ALA A 1 162 ? 31.63892  -2.06635  16.05058  1.000 33.47641  ? 158 ALA H C    1 
ATOM   2350 O O    . ALA A 1 162 ? 32.05986  -1.04946  16.61438  1.000 33.92550  ? 158 ALA H O    1 
ATOM   2351 C CB   . ALA A 1 162 ? 33.47532  -3.75608  15.99266  1.000 27.99834  ? 158 ALA H CB   1 
ATOM   2352 H H    . ALA A 1 162 ? 31.46375  -5.06967  15.63459  1.000 34.15409  ? 158 ALA H H    1 
ATOM   2353 H HA   . ALA A 1 162 ? 32.15031  -3.39211  17.51628  1.000 34.73352  ? 158 ALA H HA   1 
ATOM   2354 H HB1  . ALA A 1 162 ? 34.08580  -3.04252  16.23567  1.000 33.60484  ? 158 ALA H HB1  1 
ATOM   2355 H HB2  . ALA A 1 162 ? 33.78078  -4.59569  16.37033  1.000 33.60484  ? 158 ALA H HB2  1 
ATOM   2356 H HB3  . ALA A 1 162 ? 33.41908  -3.82875  15.02702  1.000 33.60484  ? 158 ALA H HB3  1 
ATOM   2357 N N    . LEU A 1 163 ? 30.79775  -2.01433  15.01908  1.000 27.86777  ? 159 LEU H N    1 
ATOM   2358 C CA   . LEU A 1 163 ? 30.33845  -0.76411  14.42654  1.000 25.51134  ? 159 LEU H CA   1 
ATOM   2359 C C    . LEU A 1 163 ? 28.85681  -0.58916  14.73796  1.000 30.08043  ? 159 LEU H C    1 
ATOM   2360 O O    . LEU A 1 163 ? 28.02239  -1.38022  14.28243  1.000 28.71129  ? 159 LEU H O    1 
ATOM   2361 C CB   . LEU A 1 163 ? 30.59023  -0.75899  12.91774  1.000 23.37613  ? 159 LEU H CB   1 
ATOM   2362 C CG   . LEU A 1 163 ? 30.13756  0.48500   12.15465  1.000 23.88232  ? 159 LEU H CG   1 
ATOM   2363 C CD1  . LEU A 1 163 ? 30.72779  1.75403   12.75037  1.000 26.17527  ? 159 LEU H CD1  1 
ATOM   2364 C CD2  . LEU A 1 163 ? 30.52512  0.34068   10.68929  1.000 20.32326  ? 159 LEU H CD2  1 
ATOM   2365 H H    . LEU A 1 163 ? 30.47130  -2.71165  14.63597  1.000 33.44816  ? 159 LEU H H    1 
ATOM   2366 H HA   . LEU A 1 163 ? 30.81745  -0.01637  14.81685  1.000 30.62045  ? 159 LEU H HA   1 
ATOM   2367 H HB2  . LEU A 1 163 ? 31.54484  -0.85086  12.77224  1.000 28.05819  ? 159 LEU H HB2  1 
ATOM   2368 H HB3  . LEU A 1 163 ? 30.12156  -1.51584  12.53248  1.000 28.05819  ? 159 LEU H HB3  1 
ATOM   2369 H HG   . LEU A 1 163 ? 29.17366  0.56987   12.22246  1.000 28.66562  ? 159 LEU H HG   1 
ATOM   2370 H HD11 . LEU A 1 163 ? 30.50603  2.50466   12.17742  1.000 31.41716  ? 159 LEU H HD11 1 
ATOM   2371 H HD12 . LEU A 1 163 ? 30.35393  1.89124   13.63484  1.000 31.41716  ? 159 LEU H HD12 1 
ATOM   2372 H HD13 . LEU A 1 163 ? 31.69105  1.65659   12.80989  1.000 31.41716  ? 159 LEU H HD13 1 
ATOM   2373 H HD21 . LEU A 1 163 ? 30.23045  1.12819   10.20566  1.000 24.39475  ? 159 LEU H HD21 1 
ATOM   2374 H HD22 . LEU A 1 163 ? 31.48909  0.25423   10.62462  1.000 24.39475  ? 159 LEU H HD22 1 
ATOM   2375 H HD23 . LEU A 1 163 ? 30.09696  -0.45018  10.32581  1.000 24.39475  ? 159 LEU H HD23 1 
ATOM   2376 N N    . THR A 1 164 ? 28.53180  0.44274   15.51494  1.000 29.25157  ? 160 THR H N    1 
ATOM   2377 C CA   . THR A 1 164 ? 27.14119  0.72056   15.86374  1.000 26.64352  ? 160 THR H CA   1 
ATOM   2378 C C    . THR A 1 164 ? 26.81490  2.19186   15.65829  1.000 30.43486  ? 160 THR H C    1 
ATOM   2379 O O    . THR A 1 164 ? 25.67061  2.54661   15.36008  1.000 29.63864  ? 160 THR H O    1 
ATOM   2380 C CB   . THR A 1 164 ? 26.85922  0.32442   17.31359  1.000 36.15358  ? 160 THR H CB   1 
ATOM   2381 O OG1  . THR A 1 164 ? 27.77661  0.99966   18.18136  1.000 40.44581  ? 160 THR H OG1  1 
ATOM   2382 C CG2  . THR A 1 164 ? 27.00439  -1.17795  17.49119  1.000 31.78237  ? 160 THR H CG2  1 
ATOM   2383 H H    . THR A 1 164 ? 29.09766  0.99571   15.85202  1.000 35.10872  ? 160 THR H H    1 
ATOM   2384 H HA   . THR A 1 164 ? 26.56609  0.19476   15.28607  1.000 31.97905  ? 160 THR H HA   1 
ATOM   2385 H HB   . THR A 1 164 ? 25.95162  0.57298   17.54892  1.000 43.39113  ? 160 THR H HB   1 
ATOM   2386 H HG1  . THR A 1 164 ? 27.63307  0.77886   18.97901  1.000 48.54180  ? 160 THR H HG1  1 
ATOM   2387 H HG21 . THR A 1 164 ? 26.80614  -1.42431  18.40820  1.000 38.14568  ? 160 THR H HG21 1 
ATOM   2388 H HG22 . THR A 1 164 ? 26.39092  -1.64264  16.90074  1.000 38.14568  ? 160 THR H HG22 1 
ATOM   2389 H HG23 . THR A 1 164 ? 27.91117  -1.45080  17.28094  1.000 38.14568  ? 160 THR H HG23 1 
ATOM   2390 N N    . SER A 1 165 ? 27.81720  3.05155   15.80730  1.000 30.90510  ? 161 SER H N    1 
ATOM   2391 C CA   . SER A 1 165 ? 27.60962  4.48080   15.62728  1.000 36.18912  ? 161 SER H CA   1 
ATOM   2392 C C    . SER A 1 165 ? 27.28739  4.78738   14.16949  1.000 29.83333  ? 161 SER H C    1 
ATOM   2393 O O    . SER A 1 165 ? 28.02046  4.38757   13.25898  1.000 30.06845  ? 161 SER H O    1 
ATOM   2394 C CB   . SER A 1 165 ? 28.85217  5.25087   16.07320  1.000 37.56782  ? 161 SER H CB   1 
ATOM   2395 O OG   . SER A 1 165 ? 28.71553  6.63736   15.80766  1.000 49.05010  ? 161 SER H OG   1 
ATOM   2396 H H    . SER A 1 165 ? 28.62340  2.83271   16.01164  1.000 37.09295  ? 161 SER H H    1 
ATOM   2397 H HA   . SER A 1 165 ? 26.86041  4.77140   16.17053  1.000 43.43377  ? 161 SER H HA   1 
ATOM   2398 H HB2  . SER A 1 165 ? 28.97601  5.12367   17.02681  1.000 45.08821  ? 161 SER H HB2  1 
ATOM   2399 H HB3  . SER A 1 165 ? 29.62244  4.91230   15.59054  1.000 45.08821  ? 161 SER H HB3  1 
ATOM   2400 H HG   . SER A 1 165 ? 29.41332  7.04418   16.03828  1.000 58.86696  ? 161 SER H HG   1 
ATOM   2401 N N    . GLY A 1 166 ? 26.18605  5.49784   13.95003  1.000 27.40183  ? 162 GLY H N    1 
ATOM   2402 C CA   . GLY A 1 166 ? 25.80862  5.90194   12.61468  1.000 27.69126  ? 162 GLY H CA   1 
ATOM   2403 C C    . GLY A 1 166 ? 25.02559  4.87204   11.83445  1.000 23.18472  ? 162 GLY H C    1 
ATOM   2404 O O    . GLY A 1 166 ? 24.75488  5.09643   10.64924  1.000 24.29231  ? 162 GLY H O    1 
ATOM   2405 H H    . GLY A 1 166 ? 25.64258  5.75632   14.56439  1.000 32.88903  ? 162 GLY H H    1 
ATOM   2406 H HA2  . GLY A 1 166 ? 25.26493  6.70298   12.67505  1.000 33.23634  ? 162 GLY H HA2  1 
ATOM   2407 H HA3  . GLY A 1 166 ? 26.61361  6.10374   12.11252  1.000 33.23634  ? 162 GLY H HA3  1 
ATOM   2408 N N    . VAL A 1 167 ? 24.64994  3.75491   12.45394  1.000 22.79390  ? 163 VAL H N    1 
ATOM   2409 C CA   . VAL A 1 167 ? 23.95345  2.67482   11.76027  1.000 23.70687  ? 163 VAL H CA   1 
ATOM   2410 C C    . VAL A 1 167 ? 22.45197  2.91416   11.81552  1.000 23.99745  ? 163 VAL H C    1 
ATOM   2411 O O    . VAL A 1 167 ? 21.89953  3.20910   12.87928  1.000 24.36043  ? 163 VAL H O    1 
ATOM   2412 C CB   . VAL A 1 167 ? 24.30221  1.30962   12.37659  1.000 21.05374  ? 163 VAL H CB   1 
ATOM   2413 C CG1  . VAL A 1 167 ? 23.45369  0.20662   11.73371  1.000 22.04307  ? 163 VAL H CG1  1 
ATOM   2414 C CG2  . VAL A 1 167 ? 25.77715  1.02470   12.22024  1.000 22.17564  ? 163 VAL H CG2  1 
ATOM   2415 H H    . VAL A 1 167 ? 24.78939  3.59722   13.28778  1.000 27.35952  ? 163 VAL H H    1 
ATOM   2416 H HA   . VAL A 1 167 ? 24.22719  2.68183   10.82972  1.000 28.45507  ? 163 VAL H HA   1 
ATOM   2417 H HB   . VAL A 1 167 ? 24.10269  1.32442   13.32574  1.000 25.27132  ? 163 VAL H HB   1 
ATOM   2418 H HG11 . VAL A 1 167 ? 23.86112  -0.65388  11.91930  1.000 26.45852  ? 163 VAL H HG11 1 
ATOM   2419 H HG12 . VAL A 1 167 ? 22.55959  0.23701   12.10865  1.000 26.45852  ? 163 VAL H HG12 1 
ATOM   2420 H HG13 . VAL A 1 167 ? 23.41593  0.35504   10.77588  1.000 26.45852  ? 163 VAL H HG13 1 
ATOM   2421 H HG21 . VAL A 1 167 ? 25.97093  0.14991   12.59184  1.000 26.61760  ? 163 VAL H HG21 1 
ATOM   2422 H HG22 . VAL A 1 167 ? 26.00373  1.04109   11.27722  1.000 26.61760  ? 163 VAL H HG22 1 
ATOM   2423 H HG23 . VAL A 1 167 ? 26.28200  1.70438   12.69359  1.000 26.61760  ? 163 VAL H HG23 1 
ATOM   2424 N N    . HIS A 1 168 ? 21.78727  2.77090   10.66900  1.000 19.91017  ? 164 HIS H N    1 
ATOM   2425 C CA   . HIS A 1 168 ? 20.33250  2.78578   10.57952  1.000 21.66975  ? 164 HIS H CA   1 
ATOM   2426 C C    . HIS A 1 168 ? 19.90248  1.51802   9.85914   1.000 22.12113  ? 164 HIS H C    1 
ATOM   2427 O O    . HIS A 1 168 ? 20.21749  1.33538   8.67890   1.000 19.96785  ? 164 HIS H O    1 
ATOM   2428 C CB   . HIS A 1 168 ? 19.82126  4.02173   9.83189   1.000 22.31855  ? 164 HIS H CB   1 
ATOM   2429 C CG   . HIS A 1 168 ? 20.10099  5.31504   10.53434  1.000 30.79230  ? 164 HIS H CG   1 
ATOM   2430 N ND1  . HIS A 1 168 ? 19.52612  5.64747   11.74230  1.000 26.80057  ? 164 HIS H ND1  1 
ATOM   2431 C CD2  . HIS A 1 168 ? 20.88700  6.36246   10.19136  1.000 30.83276  ? 164 HIS H CD2  1 
ATOM   2432 C CE1  . HIS A 1 168 ? 19.95526  6.83837   12.11850  1.000 31.91365  ? 164 HIS H CE1  1 
ATOM   2433 N NE2  . HIS A 1 168 ? 20.78241  7.29435   11.19467  1.000 28.10907  ? 164 HIS H NE2  1 
ATOM   2434 H H    . HIS A 1 168 ? 22.17142  2.66042   9.90754   1.000 23.89904  ? 164 HIS H H    1 
ATOM   2435 H HA   . HIS A 1 168 ? 19.95023  2.79871   11.47093  1.000 26.01053  ? 164 HIS H HA   1 
ATOM   2436 H HB2  . HIS A 1 168 ? 20.24984  4.05905   8.96251   1.000 26.78909  ? 164 HIS H HB2  1 
ATOM   2437 H HB3  . HIS A 1 168 ? 18.86019  3.94548   9.72499   1.000 26.78909  ? 164 HIS H HB3  1 
ATOM   2438 H HD1  . HIS A 1 168 ? 18.97420  5.15608   12.18222  1.000 32.16752  ? 164 HIS H HD1  1 
ATOM   2439 H HD2  . HIS A 1 168 ? 21.40166  6.43703   9.42034   1.000 37.00614  ? 164 HIS H HD2  1 
ATOM   2440 H HE1  . HIS A 1 168 ? 19.71594  7.28084   12.90071  1.000 38.30322  ? 164 HIS H HE1  1 
ATOM   2441 N N    . THR A 1 169 ? 19.18612  0.65067   10.55314  1.000 19.84732  ? 165 THR H N    1 
ATOM   2442 C CA   . THR A 1 169 ? 18.62458  -0.55364  9.95198   1.000 21.43842  ? 165 THR H CA   1 
ATOM   2443 C C    . THR A 1 169 ? 17.12320  -0.32549  9.82768   1.000 20.82180  ? 165 THR H C    1 
ATOM   2444 O O    . THR A 1 169 ? 16.42694  -0.17728  10.83464  1.000 20.84771  ? 165 THR H O    1 
ATOM   2445 C CB   . THR A 1 169 ? 18.95576  -1.79127  10.77989  1.000 21.10413  ? 165 THR H CB   1 
ATOM   2446 O OG1  . THR A 1 169 ? 20.37500  -2.00080  10.76427  1.000 21.27369  ? 165 THR H OG1  1 
ATOM   2447 C CG2  . THR A 1 169 ? 18.27373  -3.00826  10.20088  1.000 18.38075  ? 165 THR H CG2  1 
ATOM   2448 H H    . THR A 1 169 ? 19.00668  0.73692   11.38977  1.000 23.82362  ? 165 THR H H    1 
ATOM   2449 H HA   . THR A 1 169 ? 18.99448  -0.69861  9.06707   1.000 25.73294  ? 165 THR H HA   1 
ATOM   2450 H HB   . THR A 1 169 ? 18.64875  -1.66828  11.69176  1.000 25.33179  ? 165 THR H HB   1 
ATOM   2451 H HG1  . THR A 1 169 ? 20.57261  -2.66491  11.23914  1.000 25.53526  ? 165 THR H HG1  1 
ATOM   2452 H HG21 . THR A 1 169 ? 18.63520  -3.81375  10.60266  1.000 22.06373  ? 165 THR H HG21 1 
ATOM   2453 H HG22 . THR A 1 169 ? 17.32054  -2.96935  10.37643  1.000 22.06373  ? 165 THR H HG22 1 
ATOM   2454 H HG23 . THR A 1 169 ? 18.41604  -3.04358  9.24203   1.000 22.06373  ? 165 THR H HG23 1 
ATOM   2455 N N    . PHE A 1 170 ? 16.63645  -0.27094  8.60667   1.000 17.70474  ? 166 PHE H N    1 
ATOM   2456 C CA   . PHE A 1 170 ? 15.25735  0.14696   8.41964   1.000 17.69379  ? 166 PHE H CA   1 
ATOM   2457 C C    . PHE A 1 170 ? 14.28936  -0.99912  8.69274   1.000 20.58573  ? 166 PHE H C    1 
ATOM   2458 O O    . PHE A 1 170 ? 14.64921  -2.17328  8.55797   1.000 21.53141  ? 166 PHE H O    1 
ATOM   2459 C CB   . PHE A 1 170 ? 15.05768  0.67598   7.00609   1.000 17.14719  ? 166 PHE H CB   1 
ATOM   2460 C CG   . PHE A 1 170 ? 15.80750  1.94275   6.74547   1.000 19.89432  ? 166 PHE H CG   1 
ATOM   2461 C CD1  . PHE A 1 170 ? 17.11913  1.91113   6.30172   1.000 18.33254  ? 166 PHE H CD1  1 
ATOM   2462 C CD2  . PHE A 1 170 ? 15.21874  3.16732   6.98701   1.000 16.41564  ? 166 PHE H CD2  1 
ATOM   2463 C CE1  . PHE A 1 170 ? 17.81605  3.07865   6.07899   1.000 17.22761  ? 166 PHE H CE1  1 
ATOM   2464 C CE2  . PHE A 1 170 ? 15.91696  4.33913   6.77184   1.000 16.76454  ? 166 PHE H CE2  1 
ATOM   2465 C CZ   . PHE A 1 170 ? 17.21328  4.29320   6.31795   1.000 20.37238  ? 166 PHE H CZ   1 
ATOM   2466 H H    . PHE A 1 170 ? 17.06748  -0.46408  7.88798   1.000 21.25253  ? 166 PHE H H    1 
ATOM   2467 H HA   . PHE A 1 170 ? 15.04832  0.85808   9.04535   1.000 21.23938  ? 166 PHE H HA   1 
ATOM   2468 H HB2  . PHE A 1 170 ? 15.36772  0.00909   6.37360   1.000 20.58346  ? 166 PHE H HB2  1 
ATOM   2469 H HB3  . PHE A 1 170 ? 14.11417  0.85246   6.86631   1.000 20.58346  ? 166 PHE H HB3  1 
ATOM   2470 H HD1  . PHE A 1 170 ? 17.53423  1.09241   6.15236   1.000 22.00588  ? 166 PHE H HD1  1 
ATOM   2471 H HD2  . PHE A 1 170 ? 14.34297  3.20373   7.29781   1.000 19.70560  ? 166 PHE H HD2  1 
ATOM   2472 H HE1  . PHE A 1 170 ? 18.69186  3.04636   5.76786   1.000 20.67996  ? 166 PHE H HE1  1 
ATOM   2473 H HE2  . PHE A 1 170 ? 15.50990  5.15942   6.93409   1.000 20.12428  ? 166 PHE H HE2  1 
ATOM   2474 H HZ   . PHE A 1 170 ? 17.68329  5.08235   6.17223   1.000 24.45369  ? 166 PHE H HZ   1 
ATOM   2475 N N    . PRO A 1 171 ? 13.05839  -0.68325  9.09989   1.000 21.21174  ? 167 PRO H N    1 
ATOM   2476 C CA   . PRO A 1 171 ? 12.04165  -1.73098  9.22196   1.000 22.77734  ? 167 PRO H CA   1 
ATOM   2477 C C    . PRO A 1 171 ? 11.82898  -2.41355  7.88370   1.000 24.98843  ? 167 PRO H C    1 
ATOM   2478 O O    . PRO A 1 171 ? 11.95523  -1.79879  6.82439   1.000 23.20665  ? 167 PRO H O    1 
ATOM   2479 C CB   . PRO A 1 171 ? 10.78820  -0.97099  9.66919   1.000 26.48362  ? 167 PRO H CB   1 
ATOM   2480 C CG   . PRO A 1 171 ? 11.29504  0.29654   10.26620  1.000 24.56437  ? 167 PRO H CG   1 
ATOM   2481 C CD   . PRO A 1 171 ? 12.53845  0.63611   9.50385   1.000 22.50652  ? 167 PRO H CD   1 
ATOM   2482 H HA   . PRO A 1 171 ? 12.28044  -2.38093  9.90126   1.000 27.33965  ? 167 PRO H HA   1 
ATOM   2483 H HB2  . PRO A 1 171 ? 10.22091  -0.79099  8.90324   1.000 31.78718  ? 167 PRO H HB2  1 
ATOM   2484 H HB3  . PRO A 1 171 ? 10.30249  -1.49381  10.32619  1.000 31.78718  ? 167 PRO H HB3  1 
ATOM   2485 H HG2  . PRO A 1 171 ? 10.62911  0.99478   10.16665  1.000 29.48408  ? 167 PRO H HG2  1 
ATOM   2486 H HG3  . PRO A 1 171 ? 11.49420  0.15953   11.20559  1.000 29.48408  ? 167 PRO H HG3  1 
ATOM   2487 H HD2  . PRO A 1 171 ? 12.32997  1.17788   8.72673   1.000 27.01466  ? 167 PRO H HD2  1 
ATOM   2488 H HD3  . PRO A 1 171 ? 13.17509  1.09956   10.07025  1.000 27.01466  ? 167 PRO H HD3  1 
ATOM   2489 N N    . ALA A 1 172 ? 11.52073  -3.70408  7.94256   1.000 20.98883  ? 168 ALA H N    1 
ATOM   2490 C CA   . ALA A 1 172 ? 11.26930  -4.46355  6.73094   1.000 22.99279  ? 168 ALA H CA   1 
ATOM   2491 C C    . ALA A 1 172 ? 9.97406   -4.00018  6.07718   1.000 23.90716  ? 168 ALA H C    1 
ATOM   2492 O O    . ALA A 1 172 ? 9.03541   -3.55934  6.74494   1.000 22.03189  ? 168 ALA H O    1 
ATOM   2493 C CB   . ALA A 1 172 ? 11.19387  -5.95726  7.04242   1.000 28.57730  ? 168 ALA H CB   1 
ATOM   2494 H H    . ALA A 1 172 ? 11.45175  -4.15895  8.66915   1.000 25.19343  ? 168 ALA H H    1 
ATOM   2495 H HA   . ALA A 1 172 ? 11.99611  -4.32650  6.10336   1.000 27.59819  ? 168 ALA H HA   1 
ATOM   2496 H HB1  . ALA A 1 172 ? 11.03300  -6.44386  6.21887   1.000 34.29959  ? 168 ALA H HB1  1 
ATOM   2497 H HB2  . ALA A 1 172 ? 12.03418  -6.24074  7.43538   1.000 34.29959  ? 168 ALA H HB2  1 
ATOM   2498 H HB3  . ALA A 1 172 ? 10.46764  -6.11350  7.66618   1.000 34.29959  ? 168 ALA H HB3  1 
ATOM   2499 N N    . VAL A 1 173 ? 9.94147   -4.08308  4.75224   1.000 22.80509  ? 169 VAL H N    1 
ATOM   2500 C CA   . VAL A 1 173 ? 8.74730   -3.79549  3.96954   1.000 24.69533  ? 169 VAL H CA   1 
ATOM   2501 C C    . VAL A 1 173 ? 8.32932   -5.07877  3.27268   1.000 26.73455  ? 169 VAL H C    1 
ATOM   2502 O O    . VAL A 1 173 ? 9.17775   -5.83641  2.78794   1.000 27.64304  ? 169 VAL H O    1 
ATOM   2503 C CB   . VAL A 1 173 ? 8.97861   -2.67063  2.93733   1.000 28.37801  ? 169 VAL H CB   1 
ATOM   2504 C CG1  . VAL A 1 173 ? 9.50928   -1.42054  3.61542   1.000 33.85543  ? 169 VAL H CG1  1 
ATOM   2505 C CG2  . VAL A 1 173 ? 9.92483   -3.13431  1.83992   1.000 40.25230  ? 169 VAL H CG2  1 
ATOM   2506 H H    . VAL A 1 173 ? 10.61780  -4.31025  4.27206   1.000 27.37294  ? 169 VAL H H    1 
ATOM   2507 H HA   . VAL A 1 173 ? 8.03784   -3.50702  4.56482   1.000 29.64123  ? 169 VAL H HA   1 
ATOM   2508 H HB   . VAL A 1 173 ? 8.12921   -2.44844  2.52496   1.000 34.06045  ? 169 VAL H HB   1 
ATOM   2509 H HG11 . VAL A 1 173 ? 9.61640   -0.72208  2.95090   1.000 40.63335  ? 169 VAL H HG11 1 
ATOM   2510 H HG12 . VAL A 1 173 ? 8.87717   -1.13701  4.29436   1.000 40.63335  ? 169 VAL H HG12 1 
ATOM   2511 H HG13 . VAL A 1 173 ? 10.36548  -1.62228  4.02423   1.000 40.63335  ? 169 VAL H HG13 1 
ATOM   2512 H HG21 . VAL A 1 173 ? 10.25311  -2.35932  1.35772   1.000 48.30959  ? 169 VAL H HG21 1 
ATOM   2513 H HG22 . VAL A 1 173 ? 10.66670  -3.61153  2.24340   1.000 48.30959  ? 169 VAL H HG22 1 
ATOM   2514 H HG23 . VAL A 1 173 ? 9.44391   -3.72082  1.23525   1.000 48.30959  ? 169 VAL H HG23 1 
ATOM   2515 N N    . LEU A 1 174 ? 7.02307   -5.32614  3.23597   1.000 22.37724  ? 170 LEU H N    1 
ATOM   2516 C CA   . LEU A 1 174 ? 6.48185   -6.45630  2.50052   1.000 28.45690  ? 170 LEU H CA   1 
ATOM   2517 C C    . LEU A 1 174 ? 6.32789   -6.05073  1.03988   1.000 27.01118  ? 170 LEU H C    1 
ATOM   2518 O O    . LEU A 1 174 ? 5.70691   -5.02822  0.73713   1.000 25.56255  ? 170 LEU H O    1 
ATOM   2519 C CB   . LEU A 1 174 ? 5.13902   -6.88148  3.09672   1.000 28.11980  ? 170 LEU H CB   1 
ATOM   2520 C CG   . LEU A 1 174 ? 4.47635   -8.09314  2.44883   1.000 26.48128  ? 170 LEU H CG   1 
ATOM   2521 C CD1  . LEU A 1 174 ? 5.31526   -9.34051  2.65130   1.000 25.96967  ? 170 LEU H CD1  1 
ATOM   2522 C CD2  . LEU A 1 174 ? 3.07155   -8.28295  2.99992   1.000 34.06932  ? 170 LEU H CD2  1 
ATOM   2523 H H    . LEU A 1 174 ? 6.42755   -4.84906  3.63264   1.000 26.85952  ? 170 LEU H H    1 
ATOM   2524 H HA   . LEU A 1 174 ? 7.07658   -7.22067  2.55469   1.000 34.15512  ? 170 LEU H HA   1 
ATOM   2525 H HB2  . LEU A 1 174 ? 5.27738   -7.09543  4.03266   1.000 33.75059  ? 170 LEU H HB2  1 
ATOM   2526 H HB3  . LEU A 1 174 ? 4.52192   -6.13766  3.01415   1.000 33.75059  ? 170 LEU H HB3  1 
ATOM   2527 H HG   . LEU A 1 174 ? 4.40582   -7.94352  1.49304   1.000 31.78436  ? 170 LEU H HG   1 
ATOM   2528 H HD11 . LEU A 1 174 ? 4.82305   -10.10894 2.32243   1.000 31.17043  ? 170 LEU H HD11 1 
ATOM   2529 H HD12 . LEU A 1 174 ? 6.14641   -9.24524  2.16035   1.000 31.17043  ? 170 LEU H HD12 1 
ATOM   2530 H HD13 . LEU A 1 174 ? 5.50032   -9.44647  3.59757   1.000 31.17043  ? 170 LEU H HD13 1 
ATOM   2531 H HD21 . LEU A 1 174 ? 2.67005   -9.05994  2.58041   1.000 40.89002  ? 170 LEU H HD21 1 
ATOM   2532 H HD22 . LEU A 1 174 ? 3.12391   -8.41513  3.95944   1.000 40.89002  ? 170 LEU H HD22 1 
ATOM   2533 H HD23 . LEU A 1 174 ? 2.54560   -7.49201  2.80319   1.000 40.89002  ? 170 LEU H HD23 1 
ATOM   2534 N N    . GLN A 1 175 ? 6.92490   -6.82755  0.14124   1.000 25.54874  ? 171 GLN H N    1 
ATOM   2535 C CA   . GLN A 1 175 ? 6.82817   -6.57473  -1.28891  1.000 28.60510  ? 171 GLN H CA   1 
ATOM   2536 C C    . GLN A 1 175 ? 5.62047   -7.30752  -1.87140  1.000 29.48469  ? 171 GLN H C    1 
ATOM   2537 O O    . GLN A 1 175 ? 5.02544   -8.18122  -1.23727  1.000 27.10743  ? 171 GLN H O    1 
ATOM   2538 C CB   . GLN A 1 175 ? 8.10682   -7.01555  -2.00410  1.000 32.21032  ? 171 GLN H CB   1 
ATOM   2539 C CG   . GLN A 1 175 ? 9.38060   -6.35572  -1.49725  1.000 30.25616  ? 171 GLN H CG   1 
ATOM   2540 C CD   . GLN A 1 175 ? 10.62772  -7.04858  -2.00777  1.000 33.16866  ? 171 GLN H CD   1 
ATOM   2541 O OE1  . GLN A 1 175 ? 11.32283  -6.53621  -2.88443  1.000 36.58261  ? 171 GLN H OE1  1 
ATOM   2542 N NE2  . GLN A 1 175 ? 10.91925  -8.22242  -1.45868  1.000 31.10530  ? 171 GLN H NE2  1 
ATOM   2543 H H    . GLN A 1 175 ? 7.39863   -7.51737  0.33954   1.000 30.66533  ? 171 GLN H H    1 
ATOM   2544 H HA   . GLN A 1 175 ? 6.71626   -5.62236  -1.43506  1.000 34.33295  ? 171 GLN H HA   1 
ATOM   2545 H HB2  . GLN A 1 175 ? 8.20893   -7.97336  -1.88973  1.000 38.65922  ? 171 GLN H HB2  1 
ATOM   2546 H HB3  . GLN A 1 175 ? 8.02211   -6.80110  -2.94629  1.000 38.65922  ? 171 GLN H HB3  1 
ATOM   2547 H HG2  . GLN A 1 175 ? 9.40261   -5.43378  -1.79799  1.000 36.31423  ? 171 GLN H HG2  1 
ATOM   2548 H HG3  . GLN A 1 175 ? 9.39195   -6.38884  -0.52788  1.000 36.31423  ? 171 GLN H HG3  1 
ATOM   2549 H HE21 . GLN A 1 175 ? 10.41029  -8.54950  -0.84746  1.000 37.33320  ? 171 GLN H HE21 1 
ATOM   2550 H HE22 . GLN A 1 175 ? 11.61697  -8.65533  -1.71438  1.000 37.33320  ? 171 GLN H HE22 1 
ATOM   2551 N N    . SER A 1 176 ? 5.26478   -6.94189  -3.10689  1.000 30.22656  ? 172 SER H N    1 
ATOM   2552 C CA   . SER A 1 176 ? 4.11956   -7.55511  -3.77139  1.000 30.07171  ? 172 SER H CA   1 
ATOM   2553 C C    . SER A 1 176 ? 4.33448   -9.03755  -4.04353  1.000 33.17838  ? 172 SER H C    1 
ATOM   2554 O O    . SER A 1 176 ? 3.35957   -9.76568  -4.25127  1.000 33.94786  ? 172 SER H O    1 
ATOM   2555 C CB   . SER A 1 176 ? 3.82522   -6.82593  -5.08133  1.000 41.92019  ? 172 SER H CB   1 
ATOM   2556 O OG   . SER A 1 176 ? 4.99712   -6.70374  -5.87119  1.000 42.60353  ? 172 SER H OG   1 
ATOM   2557 H H    . SER A 1 176 ? 5.66896   -6.34519  -3.57612  1.000 36.27871  ? 172 SER H H    1 
ATOM   2558 H HA   . SER A 1 176 ? 3.34325   -7.46770  -3.19641  1.000 36.09288  ? 172 SER H HA   1 
ATOM   2559 H HB2  . SER A 1 176 ? 3.16106   -7.32814  -5.57891  1.000 50.31106  ? 172 SER H HB2  1 
ATOM   2560 H HB3  . SER A 1 176 ? 3.48784   -5.93923  -4.87921  1.000 50.31106  ? 172 SER H HB3  1 
ATOM   2561 H HG   . SER A 1 176 ? 5.54076   -6.18206  -5.49985  1.000 51.13107  ? 172 SER H HG   1 
ATOM   2562 N N    . SER A 1 177 ? 5.58403   -9.49785  -4.05128  1.000 32.26430  ? 173 SER H N    1 
ATOM   2563 C CA   . SER A 1 177 ? 5.87921   -10.91758 -4.18543  1.000 26.03504  ? 173 SER H CA   1 
ATOM   2564 C C    . SER A 1 177 ? 5.57782   -11.70363 -2.92193  1.000 25.33468  ? 173 SER H C    1 
ATOM   2565 O O    . SER A 1 177 ? 5.73198   -12.92912 -2.92486  1.000 27.56875  ? 173 SER H O    1 
ATOM   2566 C CB   . SER A 1 177 ? 7.35226   -11.10318 -4.53931  1.000 33.07641  ? 173 SER H CB   1 
ATOM   2567 O OG   . SER A 1 177 ? 8.16661   -10.56126 -3.50913  1.000 29.64264  ? 173 SER H OG   1 
ATOM   2568 H H    . SER A 1 177 ? 6.28306   -9.00205  -3.97958  1.000 38.72399  ? 173 SER H H    1 
ATOM   2569 H HA   . SER A 1 177 ? 5.33668   -11.27727 -4.90458  1.000 31.24889  ? 173 SER H HA   1 
ATOM   2570 H HB2  . SER A 1 177 ? 7.54207   -12.04985 -4.63253  1.000 39.69852  ? 173 SER H HB2  1 
ATOM   2571 H HB3  . SER A 1 177 ? 7.54162   -10.64328 -5.37210  1.000 39.69852  ? 173 SER H HB3  1 
ATOM   2572 H HG   . SER A 1 177 ? 8.97797   -10.64943 -3.70794  1.000 35.57800  ? 173 SER H HG   1 
ATOM   2573 N N    . GLY A 1 178 ? 5.18472   -11.03507 -1.84192  1.000 25.52703  ? 174 GLY H N    1 
ATOM   2574 C CA   . GLY A 1 178 ? 5.00488   -11.69987 -0.57277  1.000 27.71716  ? 174 GLY H CA   1 
ATOM   2575 C C    . GLY A 1 178 ? 6.27786   -11.91686 0.20845   1.000 23.74304  ? 174 GLY H C    1 
ATOM   2576 O O    . GLY A 1 178 ? 6.24128   -12.59405 1.24216   1.000 21.57451  ? 174 GLY H O    1 
ATOM   2577 H H    . GLY A 1 178 ? 5.01675   -10.19180 -1.82564  1.000 30.63927  ? 174 GLY H H    1 
ATOM   2578 H HA2  . GLY A 1 178 ? 4.40687   -11.16820 -0.02448  1.000 33.26743  ? 174 GLY H HA2  1 
ATOM   2579 H HA3  . GLY A 1 178 ? 4.60129   -12.56779 -0.73004  1.000 33.26743  ? 174 GLY H HA3  1 
ATOM   2580 N N    . LEU A 1 179 ? 7.40012   -11.36740 -0.25123  1.000 19.14217  ? 175 LEU H N    1 
ATOM   2581 C CA   . LEU A 1 179 ? 8.68442   -11.49234 0.42087   1.000 20.35323  ? 175 LEU H CA   1 
ATOM   2582 C C    . LEU A 1 179 ? 9.08342   -10.15124 1.02230   1.000 18.43314  ? 175 LEU H C    1 
ATOM   2583 O O    . LEU A 1 179 ? 8.68048   -9.09188  0.53591   1.000 24.10746  ? 175 LEU H O    1 
ATOM   2584 C CB   . LEU A 1 179 ? 9.77353   -11.96405 -0.54721  1.000 17.85194  ? 175 LEU H CB   1 
ATOM   2585 C CG   . LEU A 1 179 ? 9.51610   -13.27167 -1.29692  1.000 23.06140  ? 175 LEU H CG   1 
ATOM   2586 C CD1  . LEU A 1 179 ? 10.63243  -13.52967 -2.28570  1.000 22.61500  ? 175 LEU H CD1  1 
ATOM   2587 C CD2  . LEU A 1 179 ? 9.38553   -14.43114 -0.34882  1.000 20.70450  ? 175 LEU H CD2  1 
ATOM   2588 H H    . LEU A 1 179 ? 7.44056   -10.90326 -0.97410  1.000 22.97744  ? 175 LEU H H    1 
ATOM   2589 H HA   . LEU A 1 179 ? 8.61313   -12.14460 1.13527   1.000 24.43072  ? 175 LEU H HA   1 
ATOM   2590 H HB2  . LEU A 1 179 ? 9.89714   -11.27342 -1.21703  1.000 21.42917  ? 175 LEU H HB2  1 
ATOM   2591 H HB3  . LEU A 1 179 ? 10.59168  -12.08482 -0.04031  1.000 21.42917  ? 175 LEU H HB3  1 
ATOM   2592 H HG   . LEU A 1 179 ? 8.67827   -13.19222 -1.77925  1.000 27.68051  ? 175 LEU H HG   1 
ATOM   2593 H HD11 . LEU A 1 179 ? 10.48327  -14.38728 -2.71368  1.000 27.14483  ? 175 LEU H HD11 1 
ATOM   2594 H HD12 . LEU A 1 179 ? 10.63437  -12.82384 -2.95105  1.000 27.14483  ? 175 LEU H HD12 1 
ATOM   2595 H HD13 . LEU A 1 179 ? 11.47847  -13.53942 -1.81134  1.000 27.14483  ? 175 LEU H HD13 1 
ATOM   2596 H HD21 . LEU A 1 179 ? 9.26995   -15.24661 -0.86123  1.000 24.85224  ? 175 LEU H HD21 1 
ATOM   2597 H HD22 . LEU A 1 179 ? 10.18977  -14.49040 0.19024   1.000 24.85224  ? 175 LEU H HD22 1 
ATOM   2598 H HD23 . LEU A 1 179 ? 8.61460   -14.28708 0.22198   1.000 24.85224  ? 175 LEU H HD23 1 
ATOM   2599 N N    . TYR A 1 180 ? 9.88560   -10.20625 2.08143   1.000 18.86833  ? 176 TYR H N    1 
ATOM   2600 C CA   . TYR A 1 180 ? 10.32108  -9.00906  2.78113   1.000 17.71008  ? 176 TYR H CA   1 
ATOM   2601 C C    . TYR A 1 180 ? 11.65816  -8.50611  2.24637   1.000 18.61095  ? 176 TYR H C    1 
ATOM   2602 O O    . TYR A 1 180 ? 12.47303  -9.25741  1.70708   1.000 16.61939  ? 176 TYR H O    1 
ATOM   2603 C CB   . TYR A 1 180 ? 10.44498  -9.27389  4.28235   1.000 19.34256  ? 176 TYR H CB   1 
ATOM   2604 C CG   . TYR A 1 180 ? 9.10750   -9.43154  4.97168   1.000 20.64374  ? 176 TYR H CG   1 
ATOM   2605 C CD1  . TYR A 1 180 ? 8.37398   -8.32235  5.37088   1.000 25.17097  ? 176 TYR H CD1  1 
ATOM   2606 C CD2  . TYR A 1 180 ? 8.57459   -10.68948 5.21273   1.000 18.77725  ? 176 TYR H CD2  1 
ATOM   2607 C CE1  . TYR A 1 180 ? 7.14468   -8.46466  5.99768   1.000 26.72592  ? 176 TYR H CE1  1 
ATOM   2608 C CE2  . TYR A 1 180 ? 7.34852   -10.84292 5.83328   1.000 23.02037  ? 176 TYR H CE2  1 
ATOM   2609 C CZ   . TYR A 1 180 ? 6.63732   -9.73108  6.22265   1.000 25.10287  ? 176 TYR H CZ   1 
ATOM   2610 O OH   . TYR A 1 180 ? 5.41991   -9.88849  6.84031   1.000 28.51330  ? 176 TYR H OH   1 
ATOM   2611 H H    . TYR A 1 180 ? 10.19367  -10.93609 2.41614   1.000 22.64883  ? 176 TYR H H    1 
ATOM   2612 H HA   . TYR A 1 180 ? 9.65822   -8.31526  2.63916   1.000 21.25893  ? 176 TYR H HA   1 
ATOM   2613 H HB2  . TYR A 1 180 ? 10.94823  -10.09222 4.41643   1.000 23.21790  ? 176 TYR H HB2  1 
ATOM   2614 H HB3  . TYR A 1 180 ? 10.90780  -8.52831  4.69565   1.000 23.21790  ? 176 TYR H HB3  1 
ATOM   2615 H HD1  . TYR A 1 180 ? 8.71229   -7.47011  5.21554   1.000 30.21200  ? 176 TYR H HD1  1 
ATOM   2616 H HD2  . TYR A 1 180 ? 9.05123   -11.44424 4.95187   1.000 22.53954  ? 176 TYR H HD2  1 
ATOM   2617 H HE1  . TYR A 1 180 ? 6.66529   -7.71378  6.26462   1.000 32.07793  ? 176 TYR H HE1  1 
ATOM   2618 H HE2  . TYR A 1 180 ? 7.00603   -11.69381 5.98685   1.000 27.63128  ? 176 TYR H HE2  1 
ATOM   2619 H HH   . TYR A 1 180 ? 5.23635   -10.70526 6.90953   1.000 34.22279  ? 176 TYR H HH   1 
ATOM   2620 N N    . SER A 1 181 ? 11.88776  -7.21393  2.43671   1.000 18.41962  ? 177 SER H N    1 
ATOM   2621 C CA   . SER A 1 181 ? 13.15265  -6.59984  2.07465   1.000 17.98222  ? 177 SER H CA   1 
ATOM   2622 C C    . SER A 1 181 ? 13.41617  -5.44406  3.02539   1.000 19.33151  ? 177 SER H C    1 
ATOM   2623 O O    . SER A 1 181 ? 12.48397  -4.79906  3.51148   1.000 20.92177  ? 177 SER H O    1 
ATOM   2624 C CB   . SER A 1 181 ? 13.13306  -6.11867  0.62221   1.000 22.17161  ? 177 SER H CB   1 
ATOM   2625 O OG   . SER A 1 181 ? 14.27410  -5.34062  0.32792   1.000 25.80474  ? 177 SER H OG   1 
ATOM   2626 H H    . SER A 1 181 ? 11.31903  -6.66656  2.77809   1.000 22.11037  ? 177 SER H H    1 
ATOM   2627 H HA   . SER A 1 181 ? 13.87814  -7.23670  2.16937   1.000 21.58550  ? 177 SER H HA   1 
ATOM   2628 H HB2  . SER A 1 181 ? 13.11889  -6.89078  0.03523   1.000 26.61277  ? 177 SER H HB2  1 
ATOM   2629 H HB3  . SER A 1 181 ? 12.33941  -5.57935  0.48020   1.000 26.61277  ? 177 SER H HB3  1 
ATOM   2630 H HG   . SER A 1 181 ? 14.22908  -4.60249  0.72635   1.000 30.97252  ? 177 SER H HG   1 
ATOM   2631 N N    . LEU A 1 182 ? 14.69371  -5.20789  3.31310   1.000 18.45334  ? 178 LEU H N    1 
ATOM   2632 C CA   . LEU A 1 182 ? 15.09074  -4.03664  4.08186   1.000 20.25524  ? 178 LEU H CA   1 
ATOM   2633 C C    . LEU A 1 182 ? 16.51354  -3.65547  3.71041   1.000 22.45930  ? 178 LEU H C    1 
ATOM   2634 O O    . LEU A 1 182 ? 17.22477  -4.39798  3.03542   1.000 20.98883  ? 178 LEU H O    1 
ATOM   2635 C CB   . LEU A 1 182 ? 14.97028  -4.27261  5.59596   1.000 23.32158  ? 178 LEU H CB   1 
ATOM   2636 C CG   . LEU A 1 182 ? 15.85925  -5.30746  6.28771   1.000 16.39278  ? 178 LEU H CG   1 
ATOM   2637 C CD1  . LEU A 1 182 ? 17.31374  -4.88625  6.34819   1.000 22.61358  ? 178 LEU H CD1  1 
ATOM   2638 C CD2  . LEU A 1 182 ? 15.33445  -5.55245  7.69544   1.000 24.16611  ? 178 LEU H CD2  1 
ATOM   2639 H H    . LEU A 1 182 ? 15.34780  -5.71224  3.07350   1.000 22.15085  ? 178 LEU H H    1 
ATOM   2640 H HA   . LEU A 1 182 ? 14.50467  -3.30124  3.84393   1.000 24.31312  ? 178 LEU H HA   1 
ATOM   2641 H HB2  . LEU A 1 182 ? 15.15395  -3.42603  6.03239   1.000 27.99273  ? 178 LEU H HB2  1 
ATOM   2642 H HB3  . LEU A 1 182 ? 14.05568  -4.54439  5.77072   1.000 27.99273  ? 178 LEU H HB3  1 
ATOM   2643 H HG   . LEU A 1 182 ? 15.83071  -6.12615  5.76827   1.000 19.67817  ? 178 LEU H HG   1 
ATOM   2644 H HD11 . LEU A 1 182 ? 17.73412  -5.31134  7.11205   1.000 27.14313  ? 178 LEU H HD11 1 
ATOM   2645 H HD12 . LEU A 1 182 ? 17.75675  -5.16242  5.53065   1.000 27.14313  ? 178 LEU H HD12 1 
ATOM   2646 H HD13 . LEU A 1 182 ? 17.35964  -3.92167  6.43969   1.000 27.14313  ? 178 LEU H HD13 1 
ATOM   2647 H HD21 . LEU A 1 182 ? 15.88375  -6.22719  8.12428   1.000 29.00617  ? 178 LEU H HD21 1 
ATOM   2648 H HD22 . LEU A 1 182 ? 15.37710  -4.72336  8.19712   1.000 29.00617  ? 178 LEU H HD22 1 
ATOM   2649 H HD23 . LEU A 1 182 ? 14.41587  -5.85929  7.64108   1.000 29.00617  ? 178 LEU H HD23 1 
ATOM   2650 N N    . SER A 1 183 ? 16.91364  -2.47294  4.15322   1.000 18.47856  ? 179 SER H N    1 
ATOM   2651 C CA   . SER A 1 183 ? 18.26317  -1.97659  3.98079   1.000 18.46880  ? 179 SER H CA   1 
ATOM   2652 C C    . SER A 1 183 ? 18.82671  -1.61376  5.34394   1.000 18.09212  ? 179 SER H C    1 
ATOM   2653 O O    . SER A 1 183 ? 18.09556  -1.19847  6.24502   1.000 19.05466  ? 179 SER H O    1 
ATOM   2654 C CB   . SER A 1 183 ? 18.31104  -0.74532  3.05581   1.000 22.62407  ? 179 SER H CB   1 
ATOM   2655 O OG   . SER A 1 183 ? 18.27572  -1.12052  1.68629   1.000 27.14762  ? 179 SER H OG   1 
ATOM   2656 H H    . SER A 1 183 ? 16.40113  -1.92302  4.57097   1.000 22.18111  ? 179 SER H H    1 
ATOM   2657 H HA   . SER A 1 183 ? 18.81570  -2.66402  3.57698   1.000 22.16940  ? 179 SER H HA   1 
ATOM   2658 H HB2  . SER A 1 183 ? 17.54512  -0.18122  3.24567   1.000 27.15572  ? 179 SER H HB2  1 
ATOM   2659 H HB3  . SER A 1 183 ? 19.13230  -0.25790  3.22573   1.000 27.15572  ? 179 SER H HB3  1 
ATOM   2660 H HG   . SER A 1 183 ? 17.56878  -1.54360  1.52246   1.000 32.58398  ? 179 SER H HG   1 
ATOM   2661 N N    . SER A 1 184 ? 20.13030  -1.80796  5.49078   1.000 15.55984  ? 180 SER H N    1 
ATOM   2662 C CA   . SER A 1 184 ? 20.88859  -1.29249  6.62170   1.000 18.16612  ? 180 SER H CA   1 
ATOM   2663 C C    . SER A 1 184 ? 21.99618  -0.41449  6.06306   1.000 19.75334  ? 180 SER H C    1 
ATOM   2664 O O    . SER A 1 184 ? 22.71987  -0.83101  5.15298   1.000 17.45242  ? 180 SER H O    1 
ATOM   2665 C CB   . SER A 1 184 ? 21.47553  -2.41602  7.47399   1.000 17.03510  ? 180 SER H CB   1 
ATOM   2666 O OG   . SER A 1 184 ? 22.26517  -1.88823  8.52717   1.000 19.93097  ? 180 SER H OG   1 
ATOM   2667 H H    . SER A 1 184 ? 20.61196  -2.24877  4.93106   1.000 18.67865  ? 180 SER H H    1 
ATOM   2668 H HA   . SER A 1 184 ? 20.31416  -0.76780  7.20103   1.000 21.80618  ? 180 SER H HA   1 
ATOM   2669 H HB2  . SER A 1 184 ? 20.75040  -2.93693  7.85311   1.000 20.44895  ? 180 SER H HB2  1 
ATOM   2670 H HB3  . SER A 1 184 ? 22.03167  -2.97997  6.91402   1.000 20.44895  ? 180 SER H HB3  1 
ATOM   2671 H HG   . SER A 1 184 ? 21.80206  -1.37446  9.00379   1.000 23.92400  ? 180 SER H HG   1 
ATOM   2672 N N    . VAL A 1 185 ? 22.10188  0.80782   6.57508   1.000 15.38885  ? 181 VAL H N    1 
ATOM   2673 C CA   . VAL A 1 185 ? 23.08837  1.76380   6.10054   1.000 16.65891  ? 181 VAL H CA   1 
ATOM   2674 C C    . VAL A 1 185 ? 23.89945  2.26270   7.28529   1.000 17.08830  ? 181 VAL H C    1 
ATOM   2675 O O    . VAL A 1 185 ? 23.48582  2.17243   8.44164   1.000 19.64810  ? 181 VAL H O    1 
ATOM   2676 C CB   . VAL A 1 185 ? 22.44912  2.96038   5.36677   1.000 17.79819  ? 181 VAL H CB   1 
ATOM   2677 C CG1  . VAL A 1 185 ? 21.57588  2.48211   4.22673   1.000 18.09989  ? 181 VAL H CG1  1 
ATOM   2678 C CG2  . VAL A 1 185 ? 21.66390  3.82128   6.35058   1.000 22.82206  ? 181 VAL H CG2  1 
ATOM   2679 H H    . VAL A 1 185 ? 21.60385  1.10859   7.20841   1.000 18.47345  ? 181 VAL H H    1 
ATOM   2680 H HA   . VAL A 1 185 ? 23.68526  1.31076   5.48459   1.000 19.99752  ? 181 VAL H HA   1 
ATOM   2681 H HB   . VAL A 1 185 ? 23.14812  3.51226   4.98241   1.000 21.36467  ? 181 VAL H HB   1 
ATOM   2682 H HG11 . VAL A 1 185 ? 21.22296  3.25246   3.75460   1.000 21.72670  ? 181 VAL H HG11 1 
ATOM   2683 H HG12 . VAL A 1 185 ? 22.11074  1.94157   3.62453   1.000 21.72670  ? 181 VAL H HG12 1 
ATOM   2684 H HG13 . VAL A 1 185 ? 20.84737  1.95293   4.58747   1.000 21.72670  ? 181 VAL H HG13 1 
ATOM   2685 H HG21 . VAL A 1 185 ? 21.04588  4.38205   5.85613   1.000 27.39330  ? 181 VAL H HG21 1 
ATOM   2686 H HG22 . VAL A 1 185 ? 21.17396  3.24254   6.95550   1.000 27.39330  ? 181 VAL H HG22 1 
ATOM   2687 H HG23 . VAL A 1 185 ? 22.28404  4.37408   6.85132   1.000 27.39330  ? 181 VAL H HG23 1 
ATOM   2688 N N    . VAL A 1 186 ? 25.06936  2.79721   6.97552   1.000 17.43028  ? 182 VAL H N    1 
ATOM   2689 C CA   . VAL A 1 186 ? 25.91596  3.44068   7.96965   1.000 20.45221  ? 182 VAL H CA   1 
ATOM   2690 C C    . VAL A 1 186 ? 26.70640  4.53511   7.26757   1.000 19.65643  ? 182 VAL H C    1 
ATOM   2691 O O    . VAL A 1 186 ? 27.09273  4.39225   6.10254   1.000 22.34103  ? 182 VAL H O    1 
ATOM   2692 C CB   . VAL A 1 186 ? 26.82399  2.40302   8.67133   1.000 21.57778  ? 182 VAL H CB   1 
ATOM   2693 C CG1  . VAL A 1 186 ? 27.73856  1.71295   7.66823   1.000 21.28852  ? 182 VAL H CG1  1 
ATOM   2694 C CG2  . VAL A 1 186 ? 27.61962  3.05424   9.80596   1.000 24.45231  ? 182 VAL H CG2  1 
ATOM   2695 H H    . VAL A 1 186 ? 25.40220  2.80078   6.18255   1.000 20.92317  ? 182 VAL H H    1 
ATOM   2696 H HA   . VAL A 1 186 ? 25.37549  3.86540   8.65406   1.000 24.54948  ? 182 VAL H HA   1 
ATOM   2697 H HB   . VAL A 1 186 ? 26.26362  1.71759   9.06765   1.000 25.90017  ? 182 VAL H HB   1 
ATOM   2698 H HG11 . VAL A 1 186 ? 28.24370  1.02203   8.12469   1.000 25.55305  ? 182 VAL H HG11 1 
ATOM   2699 H HG12 . VAL A 1 186 ? 27.19720  1.31816   6.96683   1.000 25.55305  ? 182 VAL H HG12 1 
ATOM   2700 H HG13 . VAL A 1 186 ? 28.34379  2.36934   7.28908   1.000 25.55305  ? 182 VAL H HG13 1 
ATOM   2701 H HG21 . VAL A 1 186 ? 28.13779  2.37175   10.26049  1.000 29.34961  ? 182 VAL H HG21 1 
ATOM   2702 H HG22 . VAL A 1 186 ? 28.21208  3.72495   9.43173   1.000 29.34961  ? 182 VAL H HG22 1 
ATOM   2703 H HG23 . VAL A 1 186 ? 27.00128  3.46897   10.42769  1.000 29.34961  ? 182 VAL H HG23 1 
ATOM   2704 N N    . THR A 1 187 ? 26.91478  5.64843   7.96720   1.000 22.72005  ? 183 THR H N    1 
ATOM   2705 C CA   . THR A 1 187 ? 27.80143  6.70173   7.49598   1.000 26.27639  ? 183 THR H CA   1 
ATOM   2706 C C    . THR A 1 187 ? 29.13594  6.61738   8.22641   1.000 24.72136  ? 183 THR H C    1 
ATOM   2707 O O    . THR A 1 187 ? 29.18628  6.43506   9.44602   1.000 26.69200  ? 183 THR H O    1 
ATOM   2708 C CB   . THR A 1 187 ? 27.18906  8.08704   7.69515   1.000 22.37564  ? 183 THR H CB   1 
ATOM   2709 O OG1  . THR A 1 187 ? 26.73247  8.21905   9.04176   1.000 30.64335  ? 183 THR H OG1  1 
ATOM   2710 C CG2  . THR A 1 187 ? 26.02359  8.29388   6.72495   1.000 31.52300  ? 183 THR H CG2  1 
ATOM   2711 H H    . THR A 1 187 ? 26.54789  5.81581   8.72679   1.000 27.27089  ? 183 THR H H    1 
ATOM   2712 H HA   . THR A 1 187 ? 27.95589  6.58247   6.54581   1.000 31.53851  ? 183 THR H HA   1 
ATOM   2713 H HB   . THR A 1 187 ? 27.85405  8.77109   7.51976   1.000 26.85760  ? 183 THR H HB   1 
ATOM   2714 H HG1  . THR A 1 187 ? 26.11552  7.66891   9.19117   1.000 36.77885  ? 183 THR H HG1  1 
ATOM   2715 H HG21 . THR A 1 187 ? 25.63798  9.17473   6.85261   1.000 37.83443  ? 183 THR H HG21 1 
ATOM   2716 H HG22 . THR A 1 187 ? 26.33597  8.21659   5.80988   1.000 37.83443  ? 183 THR H HG22 1 
ATOM   2717 H HG23 . THR A 1 187 ? 25.33892  7.62482   6.88143   1.000 37.83443  ? 183 THR H HG23 1 
ATOM   2718 N N    . VAL A 1 188 ? 30.21338  6.75770   7.46465   1.000 25.91333  ? 184 VAL H N    1 
ATOM   2719 C CA   . VAL A 1 188 ? 31.57052  6.62062   7.98502   1.000 29.04409  ? 184 VAL H CA   1 
ATOM   2720 C C    . VAL A 1 188 ? 32.41814  7.76015   7.43079   1.000 29.68355  ? 184 VAL H C    1 
ATOM   2721 O O    . VAL A 1 188 ? 32.03233  8.43400   6.47619   1.000 31.90137  ? 184 VAL H O    1 
ATOM   2722 C CB   . VAL A 1 188 ? 32.19302  5.26339   7.60514   1.000 33.65536  ? 184 VAL H CB   1 
ATOM   2723 C CG1  . VAL A 1 188 ? 31.40816  4.13342   8.24360   1.000 30.09435  ? 184 VAL H CG1  1 
ATOM   2724 C CG2  . VAL A 1 188 ? 32.23579  5.09277   6.08388   1.000 27.81850  ? 184 VAL H CG2  1 
ATOM   2725 H H    . VAL A 1 188 ? 30.18576  6.93654   6.62391   1.000 31.10283  ? 184 VAL H H    1 
ATOM   2726 H HA   . VAL A 1 188 ? 31.56013  6.68711   8.95268   1.000 34.85975  ? 184 VAL H HA   1 
ATOM   2727 H HB   . VAL A 1 188 ? 33.10472  5.23238   7.93490   1.000 40.39326  ? 184 VAL H HB   1 
ATOM   2728 H HG11 . VAL A 1 188 ? 31.75767  3.28661   7.92477   1.000 36.12006  ? 184 VAL H HG11 1 
ATOM   2729 H HG12 . VAL A 1 188 ? 31.50269  4.18845   9.20742   1.000 36.12006  ? 184 VAL H HG12 1 
ATOM   2730 H HG13 . VAL A 1 188 ? 30.47386  4.21938   7.99743   1.000 36.12006  ? 184 VAL H HG13 1 
ATOM   2731 H HG21 . VAL A 1 188 ? 32.52950  4.19215   5.87525   1.000 33.38903  ? 184 VAL H HG21 1 
ATOM   2732 H HG22 . VAL A 1 188 ? 31.34751  5.24267   5.72419   1.000 33.38903  ? 184 VAL H HG22 1 
ATOM   2733 H HG23 . VAL A 1 188 ? 32.85683  5.73792   5.71108   1.000 33.38903  ? 184 VAL H HG23 1 
ATOM   2734 N N    . PRO A 1 189 ? 33.56945  8.00514   8.05294   1.000 34.76200  ? 185 PRO H N    1 
ATOM   2735 C CA   . PRO A 1 189 ? 34.51508  8.96068   7.45971   1.000 30.59415  ? 185 PRO H CA   1 
ATOM   2736 C C    . PRO A 1 189 ? 34.96591  8.46825   6.09559   1.000 38.14980  ? 185 PRO H C    1 
ATOM   2737 O O    . PRO A 1 189 ? 35.36547  7.31281   5.93570   1.000 40.41704  ? 185 PRO H O    1 
ATOM   2738 C CB   . PRO A 1 189 ? 35.66608  8.98943   8.47118   1.000 33.46483  ? 185 PRO H CB   1 
ATOM   2739 C CG   . PRO A 1 189 ? 35.04982  8.55975   9.75808   1.000 31.95908  ? 185 PRO H CG   1 
ATOM   2740 C CD   . PRO A 1 189 ? 34.01147  7.54569   9.37909   1.000 30.63886  ? 185 PRO H CD   1 
ATOM   2741 H HA   . PRO A 1 189 ? 34.13104  9.84834   7.38566   1.000 36.71981  ? 185 PRO H HA   1 
ATOM   2742 H HB2  . PRO A 1 189 ? 36.36381  8.37404   8.19667   1.000 40.16463  ? 185 PRO H HB2  1 
ATOM   2743 H HB3  . PRO A 1 189 ? 36.02451  9.88817   8.53974   1.000 40.16463  ? 185 PRO H HB3  1 
ATOM   2744 H HG2  . PRO A 1 189 ? 35.72538  8.16515   10.33150  1.000 38.35772  ? 185 PRO H HG2  1 
ATOM   2745 H HG3  . PRO A 1 189 ? 34.64374  9.32193   10.19977  1.000 38.35772  ? 185 PRO H HG3  1 
ATOM   2746 H HD2  . PRO A 1 189 ? 34.39755  6.65735   9.32702   1.000 36.77346  ? 185 PRO H HD2  1 
ATOM   2747 H HD3  . PRO A 1 189 ? 33.27529  7.55098   10.01069  1.000 36.77346  ? 185 PRO H HD3  1 
ATOM   2748 N N    . SER A 1 190 ? 34.87301  9.34652   5.09554   1.000 32.17957  ? 186 SER H N    1 
ATOM   2749 C CA   . SER A 1 190 ? 35.26657  8.94650   3.75023   1.000 36.55074  ? 186 SER H CA   1 
ATOM   2750 C C    . SER A 1 190 ? 36.72986  8.52594   3.71679   1.000 40.11527  ? 186 SER H C    1 
ATOM   2751 O O    . SER A 1 190 ? 37.09151  7.55574   3.03693   1.000 45.01461  ? 186 SER H O    1 
ATOM   2752 C CB   . SER A 1 190 ? 34.99917  10.08333  2.76351   1.000 42.06062  ? 186 SER H CB   1 
ATOM   2753 O OG   . SER A 1 190 ? 35.60481  11.28938  3.19095   1.000 43.17554  ? 186 SER H OG   1 
ATOM   2754 H H    . SER A 1 190 ? 34.59309  10.15634  5.16937   1.000 38.62232  ? 186 SER H H    1 
ATOM   2755 H HA   . SER A 1 190 ? 34.72985  8.18746   3.47332   1.000 43.86772  ? 186 SER H HA   1 
ATOM   2756 H HB2  . SER A 1 190 ? 35.36243  9.83939   1.89781   1.000 50.47958  ? 186 SER H HB2  1 
ATOM   2757 H HB3  . SER A 1 190 ? 34.04136  10.22035  2.69473   1.000 50.47958  ? 186 SER H HB3  1 
ATOM   2758 H HG   . SER A 1 190 ? 35.43831  11.90427  2.64342   1.000 51.81748  ? 186 SER H HG   1 
ATOM   2759 N N    . SER A 1 191 ? 37.58257  9.22673   4.47162   1.000 42.02492  ? 187 SER H N    1 
ATOM   2760 C CA   . SER A 1 191 ? 38.99401  8.86278   4.54252   1.000 45.21910  ? 187 SER H CA   1 
ATOM   2761 C C    . SER A 1 191 ? 39.18727  7.39431   4.89974   1.000 48.86718  ? 187 SER H C    1 
ATOM   2762 O O    . SER A 1 191 ? 40.16429  6.77170   4.46590   1.000 47.33788  ? 187 SER H O    1 
ATOM   2763 C CB   . SER A 1 191 ? 39.70676  9.73779   5.57585   1.000 44.16337  ? 187 SER H CB   1 
ATOM   2764 O OG   . SER A 1 191 ? 39.51790  9.22330   6.88451   1.000 49.87214  ? 187 SER H OG   1 
ATOM   2765 H H    . SER A 1 191 ? 37.36845  9.91063   4.94706   1.000 50.43673  ? 187 SER H H    1 
ATOM   2766 H HA   . SER A 1 191 ? 39.39432  9.01882   3.67286   1.000 54.26975  ? 187 SER H HA   1 
ATOM   2767 H HB2  . SER A 1 191 ? 40.65585  9.75371   5.37613   1.000 53.00288  ? 187 SER H HB2  1 
ATOM   2768 H HB3  . SER A 1 191 ? 39.34377  10.63632  5.53377   1.000 53.00288  ? 187 SER H HB3  1 
ATOM   2769 H HG   . SER A 1 191 ? 39.94960  9.68333   7.43914   1.000 59.85340  ? 187 SER H HG   1 
ATOM   2770 N N    . SER A 1 192 ? 38.27250  6.82535   5.68790   1.000 42.64109  ? 188 SER H N    1 
ATOM   2771 C CA   . SER A 1 192 ? 38.41732  5.46045   6.17341   1.000 42.51981  ? 188 SER H CA   1 
ATOM   2772 C C    . SER A 1 192 ? 38.09788  4.40151   5.12540   1.000 41.87627  ? 188 SER H C    1 
ATOM   2773 O O    . SER A 1 192 ? 38.30115  3.21441   5.39787   1.000 47.44375  ? 188 SER H O    1 
ATOM   2774 C CB   . SER A 1 192 ? 37.51128  5.23716   7.38962   1.000 43.60690  ? 188 SER H CB   1 
ATOM   2775 O OG   . SER A 1 192 ? 36.15352  5.09728   6.99708   1.000 48.65483  ? 188 SER H OG   1 
ATOM   2776 H H    . SER A 1 192 ? 37.55440  7.21559   5.95558   1.000 51.17614  ? 188 SER H H    1 
ATOM   2777 H HA   . SER A 1 192 ? 39.34043  5.33908   6.44552   1.000 51.03061  ? 188 SER H HA   1 
ATOM   2778 H HB2  . SER A 1 192 ? 37.79160  4.42884   7.84671   1.000 52.33512  ? 188 SER H HB2  1 
ATOM   2779 H HB3  . SER A 1 192 ? 37.58992  5.99909   7.98475   1.000 52.33512  ? 188 SER H HB3  1 
ATOM   2780 H HG   . SER A 1 192 ? 35.90509  5.77907   6.57394   1.000 58.39262  ? 188 SER H HG   1 
ATOM   2781 N N    . LEU A 1 193 ? 37.60972  4.78031   3.94134   1.000 38.19054  ? 189 LEU H N    1 
ATOM   2782 C CA   . LEU A 1 193 ? 37.17418  3.75728   2.99463   1.000 36.63198  ? 189 LEU H CA   1 
ATOM   2783 C C    . LEU A 1 193 ? 38.33179  2.87513   2.53906   1.000 41.29765  ? 189 LEU H C    1 
ATOM   2784 O O    . LEU A 1 193 ? 38.12936  1.68978   2.25000   1.000 39.93024  ? 189 LEU H O    1 
ATOM   2785 C CB   . LEU A 1 193 ? 36.48526  4.40785   1.79564   1.000 37.98225  ? 189 LEU H CB   1 
ATOM   2786 C CG   . LEU A 1 193 ? 35.14964  5.08148   2.12566   1.000 34.54212  ? 189 LEU H CG   1 
ATOM   2787 C CD1  . LEU A 1 193 ? 34.56907  5.78648   0.91557   1.000 39.08524  ? 189 LEU H CD1  1 
ATOM   2788 C CD2  . LEU A 1 193 ? 34.16238  4.06723   2.66539   1.000 34.81989  ? 189 LEU H CD2  1 
ATOM   2789 H H    . LEU A 1 193 ? 37.52396  5.59292   3.67316   1.000 45.83548  ? 189 LEU H H    1 
ATOM   2790 H HA   . LEU A 1 193 ? 36.52570  3.18485   3.43361   1.000 43.96521  ? 189 LEU H HA   1 
ATOM   2791 H HB2  . LEU A 1 193 ? 37.07501  5.08607   1.43080   1.000 45.58553  ? 189 LEU H HB2  1 
ATOM   2792 H HB3  . LEU A 1 193 ? 36.31363  3.72416   1.12930   1.000 45.58553  ? 189 LEU H HB3  1 
ATOM   2793 H HG   . LEU A 1 193 ? 35.30882  5.75248   2.80781   1.000 41.45737  ? 189 LEU H HG   1 
ATOM   2794 H HD11 . LEU A 1 193 ? 33.73794  6.21725   1.16965   1.000 46.90912  ? 189 LEU H HD11 1 
ATOM   2795 H HD12 . LEU A 1 193 ? 35.20333  6.45016   0.60228   1.000 46.90912  ? 189 LEU H HD12 1 
ATOM   2796 H HD13 . LEU A 1 193 ? 34.40314  5.13259   0.21858   1.000 46.90912  ? 189 LEU H HD13 1 
ATOM   2797 H HD21 . LEU A 1 193 ? 33.27053  4.44743   2.63485   1.000 41.79070  ? 189 LEU H HD21 1 
ATOM   2798 H HD22 . LEU A 1 193 ? 34.19998  3.26752   2.11769   1.000 41.79070  ? 189 LEU H HD22 1 
ATOM   2799 H HD23 . LEU A 1 193 ? 34.39920  3.85238   3.58117   1.000 41.79070  ? 189 LEU H HD23 1 
ATOM   2800 N N    . GLY A 1 194 ? 39.54373  3.41925   2.47773   1.000 47.52174  ? 190 GLY H N    1 
ATOM   2801 C CA   . GLY A 1 194 ? 40.70013  2.63315   2.08962   1.000 50.61636  ? 190 GLY H CA   1 
ATOM   2802 C C    . GLY A 1 194 ? 41.37141  1.94039   3.25889   1.000 50.73872  ? 190 GLY H C    1 
ATOM   2803 O O    . GLY A 1 194 ? 42.10085  0.96132   3.07471   1.000 49.99267  ? 190 GLY H O    1 
ATOM   2804 H H    . GLY A 1 194 ? 39.71870  4.24201   2.65678   1.000 57.03292  ? 190 GLY H H    1 
ATOM   2805 H HA2  . GLY A 1 194 ? 40.42399  1.95438   1.45407   1.000 60.74646  ? 190 GLY H HA2  1 
ATOM   2806 H HA3  . GLY A 1 194 ? 41.35215  3.21429   1.66767   1.000 60.74646  ? 190 GLY H HA3  1 
ATOM   2807 N N    . THR A 1 195 ? 41.12708  2.44112   4.47097   1.000 56.39701  ? 191 THR H N    1 
ATOM   2808 C CA   . THR A 1 195 ? 41.76020  1.91687   5.67512   1.000 59.29976  ? 191 THR H CA   1 
ATOM   2809 C C    . THR A 1 195 ? 40.96733  0.78264   6.31494   1.000 57.13573  ? 191 THR H C    1 
ATOM   2810 O O    . THR A 1 195 ? 41.56062  -0.16451  6.84308   1.000 45.99797  ? 191 THR H O    1 
ATOM   2811 C CB   . THR A 1 195 ? 41.93109  3.03473   6.71053   1.000 56.72395  ? 191 THR H CB   1 
ATOM   2812 O OG1  . THR A 1 195 ? 42.29090  4.25621   6.05281   1.000 63.95723  ? 191 THR H OG1  1 
ATOM   2813 C CG2  . THR A 1 195 ? 43.00505  2.66530   7.73445   1.000 55.04090  ? 191 THR H CG2  1 
ATOM   2814 H H    . THR A 1 195 ? 40.58949  3.09515   4.62207   1.000 67.68325  ? 191 THR H H    1 
ATOM   2815 H HA   . THR A 1 195 ? 42.63477  1.57828   5.42735   1.000 71.16654  ? 191 THR H HA   1 
ATOM   2816 H HB   . THR A 1 195 ? 41.09451  3.16312   7.18440   1.000 68.07557  ? 191 THR H HB   1 
ATOM   2817 H HG1  . THR A 1 195 ? 42.32682  4.88314   6.61073   1.000 76.75552  ? 191 THR H HG1  1 
ATOM   2818 H HG21 . THR A 1 195 ? 43.09632  3.37438   8.39002   1.000 66.05591  ? 191 THR H HG21 1 
ATOM   2819 H HG22 . THR A 1 195 ? 42.76056  1.84472   8.19028   1.000 66.05591  ? 191 THR H HG22 1 
ATOM   2820 H HG23 . THR A 1 195 ? 43.85728  2.53634   7.28951   1.000 66.05591  ? 191 THR H HG23 1 
ATOM   2821 N N    . GLN A 1 196 ? 39.63819  0.86045   6.27437   1.000 47.39651  ? 192 GLN H N    1 
ATOM   2822 C CA   . GLN A 1 196 ? 38.77062  0.05982   7.12526   1.000 39.23528  ? 192 GLN H CA   1 
ATOM   2823 C C    . GLN A 1 196 ? 37.87006  -0.84520  6.29702   1.000 35.96562  ? 192 GLN H C    1 
ATOM   2824 O O    . GLN A 1 196 ? 37.27501  -0.41415  5.30392   1.000 34.54968  ? 192 GLN H O    1 
ATOM   2825 C CB   . GLN A 1 196 ? 37.91554  0.97472   8.01226   1.000 38.52268  ? 192 GLN H CB   1 
ATOM   2826 C CG   . GLN A 1 196 ? 36.89871  0.25738   8.88639   1.000 36.75392  ? 192 GLN H CG   1 
ATOM   2827 C CD   . GLN A 1 196 ? 37.54205  -0.55857  9.98874   1.000 47.73651  ? 192 GLN H CD   1 
ATOM   2828 O OE1  . GLN A 1 196 ? 38.35554  -0.04889  10.76137  1.000 45.47560  ? 192 GLN H OE1  1 
ATOM   2829 N NE2  . GLN A 1 196 ? 37.17799  -1.83529  10.06865  1.000 41.67349  ? 192 GLN H NE2  1 
ATOM   2830 H H    . GLN A 1 196 ? 39.20747  1.38521   5.74645   1.000 56.88264  ? 192 GLN H H    1 
ATOM   2831 H HA   . GLN A 1 196 ? 39.31450  -0.51849  7.68262   1.000 47.08917  ? 192 GLN H HA   1 
ATOM   2832 H HB2  . GLN A 1 196 ? 38.50607  1.47064   8.60068   1.000 46.23404  ? 192 GLN H HB2  1 
ATOM   2833 H HB3  . GLN A 1 196 ? 37.42657  1.58677   7.44025   1.000 46.23404  ? 192 GLN H HB3  1 
ATOM   2834 H HG2  . GLN A 1 196 ? 36.31835  0.91518   9.30037   1.000 44.11153  ? 192 GLN H HG2  1 
ATOM   2835 H HG3  . GLN A 1 196 ? 36.37639  -0.34490  8.33381   1.000 44.11153  ? 192 GLN H HG3  1 
ATOM   2836 H HE21 . GLN A 1 196 ? 36.60603  -2.15500  9.51166   1.000 50.01503  ? 192 GLN H HE21 1 
ATOM   2837 H HE22 . GLN A 1 196 ? 37.51456  -2.34111  10.67731  1.000 50.01503  ? 192 GLN H HE22 1 
ATOM   2838 N N    . THR A 1 197 ? 37.75718  -2.09606  6.73117   1.000 31.96657  ? 193 THR H N    1 
ATOM   2839 C CA   . THR A 1 197 ? 36.86397  -3.06034  6.10866   1.000 28.76544  ? 193 THR H CA   1 
ATOM   2840 C C    . THR A 1 197 ? 35.48816  -2.96729  6.75622   1.000 24.72390  ? 193 THR H C    1 
ATOM   2841 O O    . THR A 1 197 ? 35.36939  -2.79007  7.97073   1.000 28.77436  ? 193 THR H O    1 
ATOM   2842 C CB   . THR A 1 197 ? 37.42648  -4.47546  6.24158   1.000 33.19123  ? 193 THR H CB   1 
ATOM   2843 O OG1  . THR A 1 197 ? 38.62006  -4.58810  5.45556   1.000 43.71269  ? 193 THR H OG1  1 
ATOM   2844 C CG2  . THR A 1 197 ? 36.41821  -5.50325  5.76444   1.000 37.72793  ? 193 THR H CG2  1 
ATOM   2845 H H    . THR A 1 197 ? 38.19690  -2.41474  7.39802   1.000 38.36672  ? 193 THR H H    1 
ATOM   2846 H HA   . THR A 1 197 ? 36.77133  -2.86966  5.16211   1.000 34.52536  ? 193 THR H HA   1 
ATOM   2847 H HB   . THR A 1 197 ? 37.62707  -4.65589  7.17330   1.000 39.83631  ? 193 THR H HB   1 
ATOM   2848 H HG1  . THR A 1 197 ? 38.93211  -5.36558  5.51684   1.000 52.46206  ? 193 THR H HG1  1 
ATOM   2849 H HG21 . THR A 1 197 ? 36.86752  -6.33772  5.55786   1.000 45.28035  ? 193 THR H HG21 1 
ATOM   2850 H HG22 . THR A 1 197 ? 35.75665  -5.66455  6.45525   1.000 45.28035  ? 193 THR H HG22 1 
ATOM   2851 H HG23 . THR A 1 197 ? 35.96885  -5.18189  4.96713   1.000 45.28035  ? 193 THR H HG23 1 
ATOM   2852 N N    . TYR A 1 198 ? 34.44781  -3.05258  5.93133   1.000 26.44816  ? 194 TYR H N    1 
ATOM   2853 C CA   . TYR A 1 198 ? 33.07085  -2.95356  6.39752   1.000 21.59267  ? 194 TYR H CA   1 
ATOM   2854 C C    . TYR A 1 198 ? 32.30332  -4.17417  5.92272   1.000 21.36763  ? 194 TYR H C    1 
ATOM   2855 O O    . TYR A 1 198 ? 32.20132  -4.42129  4.71705   1.000 22.64692  ? 194 TYR H O    1 
ATOM   2856 C CB   . TYR A 1 198 ? 32.41061  -1.66899  5.90054   1.000 21.03966  ? 194 TYR H CB   1 
ATOM   2857 C CG   . TYR A 1 198 ? 33.03931  -0.42922  6.48963   1.000 16.95633  ? 194 TYR H CG   1 
ATOM   2858 C CD1  . TYR A 1 198 ? 32.74591  -0.03184  7.78289   1.000 21.71079  ? 194 TYR H CD1  1 
ATOM   2859 C CD2  . TYR A 1 198 ? 33.93421  0.33240   5.75704   1.000 21.97936  ? 194 TYR H CD2  1 
ATOM   2860 C CE1  . TYR A 1 198 ? 33.32753  1.09786   8.33276   1.000 26.79463  ? 194 TYR H CE1  1 
ATOM   2861 C CE2  . TYR A 1 198 ? 34.51590  1.46377   6.29238   1.000 27.57187  ? 194 TYR H CE2  1 
ATOM   2862 C CZ   . TYR A 1 198 ? 34.20985  1.84068   7.58223   1.000 31.21714  ? 194 TYR H CZ   1 
ATOM   2863 O OH   . TYR A 1 198 ? 34.78895  2.96396   8.12474   1.000 30.33094  ? 194 TYR H OH   1 
ATOM   2864 H H    . TYR A 1 198 ? 34.51728  -3.16987  5.08220   1.000 31.74463  ? 194 TYR H H    1 
ATOM   2865 H HA   . TYR A 1 198 ? 33.05750  -2.94668  7.36741   1.000 25.91804  ? 194 TYR H HA   1 
ATOM   2866 H HB2  . TYR A 1 198 ? 32.49754  -1.62132  4.93562   1.000 25.25443  ? 194 TYR H HB2  1 
ATOM   2867 H HB3  . TYR A 1 198 ? 31.47305  -1.67840  6.14912   1.000 25.25443  ? 194 TYR H HB3  1 
ATOM   2868 H HD1  . TYR A 1 198 ? 32.14836  -0.53190  8.29061   1.000 26.05978  ? 194 TYR H HD1  1 
ATOM   2869 H HD2  . TYR A 1 198 ? 34.14712  0.07693   4.88854   1.000 26.38207  ? 194 TYR H HD2  1 
ATOM   2870 H HE1  . TYR A 1 198 ? 33.12329  1.35294   9.20346   1.000 32.16039  ? 194 TYR H HE1  1 
ATOM   2871 H HE2  . TYR A 1 198 ? 35.11057  1.96854   5.78595   1.000 33.09308  ? 194 TYR H HE2  1 
ATOM   2872 H HH   . TYR A 1 198 ? 35.31003  3.31604   7.56785   1.000 36.40396  ? 194 TYR H HH   1 
ATOM   2873 N N    . ILE A 1 199 ? 31.76702  -4.92770  6.87425   1.000 21.80365  ? 195 ILE H N    1 
ATOM   2874 C CA   . ILE A 1 199 ? 31.05665  -6.16607  6.60648   1.000 18.37333  ? 195 ILE H CA   1 
ATOM   2875 C C    . ILE A 1 199 ? 29.72327  -6.09745  7.32772   1.000 20.17169  ? 195 ILE H C    1 
ATOM   2876 O O    . ILE A 1 199 ? 29.67964  -5.81958  8.53159   1.000 17.54688  ? 195 ILE H O    1 
ATOM   2877 C CB   . ILE A 1 199 ? 31.85862  -7.39706  7.07854   1.000 24.61967  ? 195 ILE H CB   1 
ATOM   2878 C CG1  . ILE A 1 199 ? 33.26839  -7.38776  6.48052   1.000 24.99910  ? 195 ILE H CG1  1 
ATOM   2879 C CG2  . ILE A 1 199 ? 31.12662  -8.68232  6.70086   1.000 25.68344  ? 195 ILE H CG2  1 
ATOM   2880 C CD1  . ILE A 1 199 ? 34.13994  -8.55473  6.93118   1.000 32.04663  ? 195 ILE H CD1  1 
ATOM   2881 H H    . ILE A 1 199 ? 31.80419  -4.73354  7.71122   1.000 26.17121  ? 195 ILE H H    1 
ATOM   2882 H HA   . ILE A 1 199 ? 30.89613  -6.25296  5.65381   1.000 22.05483  ? 195 ILE H HA   1 
ATOM   2883 H HB   . ILE A 1 199 ? 31.93843  -7.35498  8.04433   1.000 29.55044  ? 195 ILE H HB   1 
ATOM   2884 H HG12 . ILE A 1 199 ? 33.19661  -7.42897  5.51406   1.000 30.00576  ? 195 ILE H HG12 1 
ATOM   2885 H HG13 . ILE A 1 199 ? 33.71329  -6.56754  6.74548   1.000 30.00576  ? 195 ILE H HG13 1 
ATOM   2886 H HG21 . ILE A 1 199 ? 31.61772  -9.44078  7.05366   1.000 30.82697  ? 195 ILE H HG21 1 
ATOM   2887 H HG22 . ILE A 1 199 ? 30.23418  -8.66064  7.08031   1.000 30.82697  ? 195 ILE H HG22 1 
ATOM   2888 H HG23 . ILE A 1 199 ? 31.07367  -8.74321  5.73422   1.000 30.82697  ? 195 ILE H HG23 1 
ATOM   2889 H HD11 . ILE A 1 199 ? 35.05845  -8.38143  6.67196   1.000 38.46279  ? 195 ILE H HD11 1 
ATOM   2890 H HD12 . ILE A 1 199 ? 34.07894  -8.64049  7.89545   1.000 38.46279  ? 195 ILE H HD12 1 
ATOM   2891 H HD13 . ILE A 1 199 ? 33.82400  -9.36741  6.50616   1.000 38.46279  ? 195 ILE H HD13 1 
ATOM   2892 N N    . CYS A 1 200 ? 28.64010  -6.35393  6.60514   1.000 20.43506  ? 196 CYS H N    1 
ATOM   2893 C CA   . CYS A 1 200 ? 27.33528  -6.49498  7.23105   1.000 22.25004  ? 196 CYS H CA   1 
ATOM   2894 C C    . CYS A 1 200 ? 27.07689  -7.97568  7.46543   1.000 18.05384  ? 196 CYS H C    1 
ATOM   2895 O O    . CYS A 1 200 ? 27.32110  -8.80596  6.58056   1.000 21.78766  ? 196 CYS H O    1 
ATOM   2896 C CB   . CYS A 1 200 ? 26.22277  -5.86120  6.39371   1.000 24.43120  ? 196 CYS H CB   1 
ATOM   2897 S SG   . CYS A 1 200 ? 25.71101  -6.76001  4.96806   1.000 32.67680  ? 196 CYS H SG   1 
ATOM   2898 H H    . CYS A 1 200 ? 28.63734  -6.45028  5.75056   1.000 24.52890  ? 196 CYS H H    1 
ATOM   2899 H HA   . CYS A 1 200 ? 27.32709  -6.03421  8.08459   1.000 26.70688  ? 196 CYS H HA   1 
ATOM   2900 H HB2  . CYS A 1 200 ? 25.44214  -5.75520  6.95964   1.000 29.32428  ? 196 CYS H HB2  1 
ATOM   2901 H HB3  . CYS A 1 200 ? 26.53156  -4.99378  6.08854   1.000 29.32428  ? 196 CYS H HB3  1 
ATOM   2902 N N    . ASN A 1 201 ? 26.62109  -8.29353  8.67059   1.000 16.76733  ? 197 ASN H N    1 
ATOM   2903 C CA   . ASN A 1 201 ? 26.33245  -9.64548  9.12232   1.000 17.18583  ? 197 ASN H CA   1 
ATOM   2904 C C    . ASN A 1 201 ? 24.82057  -9.75309  9.25129   1.000 19.52960  ? 197 ASN H C    1 
ATOM   2905 O O    . ASN A 1 201 ? 24.21015  -9.08941  10.09861  1.000 19.88210  ? 197 ASN H O    1 
ATOM   2906 C CB   . ASN A 1 201 ? 27.02677  -9.92702  10.44804  1.000 23.47443  ? 197 ASN H CB   1 
ATOM   2907 C CG   . ASN A 1 201 ? 28.37690  -9.24530  10.54733  1.000 25.51555  ? 197 ASN H CG   1 
ATOM   2908 O OD1  . ASN A 1 201 ? 28.53692  -8.25361  11.26849  1.000 28.50236  ? 197 ASN H OD1  1 
ATOM   2909 N ND2  . ASN A 1 201 ? 29.35447  -9.76486  9.81664   1.000 24.00076  ? 197 ASN H ND2  1 
ATOM   2910 H H    . ASN A 1 201 ? 26.46226  -7.70711  9.27926   1.000 20.12763  ? 197 ASN H H    1 
ATOM   2911 H HA   . ASN A 1 201 ? 26.64525  -10.29832 8.47668   1.000 20.62983  ? 197 ASN H HA   1 
ATOM   2912 H HB2  . ASN A 1 201 ? 26.47061  -9.60204  11.17328  1.000 28.17615  ? 197 ASN H HB2  1 
ATOM   2913 H HB3  . ASN A 1 201 ? 27.16413  -10.88302 10.53802  1.000 28.17615  ? 197 ASN H HB3  1 
ATOM   2914 H HD21 . ASN A 1 201 ? 30.13970  -9.41476  9.83765   1.000 28.80775  ? 197 ASN H HD21 1 
ATOM   2915 H HD22 . ASN A 1 201 ? 29.20304  -10.45181 9.32191   1.000 28.80775  ? 197 ASN H HD22 1 
ATOM   2916 N N    . VAL A 1 202 ? 24.22187  -10.56857 8.39745   1.000 17.50865  ? 198 VAL H N    1 
ATOM   2917 C CA   . VAL A 1 202 ? 22.78380  -10.75987 8.34044   1.000 17.16155  ? 198 VAL H CA   1 
ATOM   2918 C C    . VAL A 1 202 ? 22.48052  -12.15055 8.86826   1.000 17.26050  ? 198 VAL H C    1 
ATOM   2919 O O    . VAL A 1 202 ? 23.10662  -13.12963 8.45111   1.000 19.47689  ? 198 VAL H O    1 
ATOM   2920 C CB   . VAL A 1 202 ? 22.26152  -10.58644 6.90505   1.000 16.62373  ? 198 VAL H CB   1 
ATOM   2921 C CG1  . VAL A 1 202 ? 20.75712  -10.66411 6.88470   1.000 16.72898  ? 198 VAL H CG1  1 
ATOM   2922 C CG2  . VAL A 1 202 ? 22.75125  -9.26228  6.32111   1.000 21.31477  ? 198 VAL H CG2  1 
ATOM   2923 H H    . VAL A 1 202 ? 24.64641  -11.04099 7.81763   1.000 21.01721  ? 198 VAL H H    1 
ATOM   2924 H HA   . VAL A 1 202 ? 22.33932  -10.11090 8.90804   1.000 20.60070  ? 198 VAL H HA   1 
ATOM   2925 H HB   . VAL A 1 202 ? 22.60476  -11.30320 6.34887   1.000 19.95531  ? 198 VAL H HB   1 
ATOM   2926 H HG11 . VAL A 1 202 ? 20.44109  -10.43574 5.99652   1.000 20.08161  ? 198 VAL H HG11 1 
ATOM   2927 H HG12 . VAL A 1 202 ? 20.48443  -11.56711 7.11080   1.000 20.08161  ? 198 VAL H HG12 1 
ATOM   2928 H HG13 . VAL A 1 202 ? 20.39978  -10.03831 7.53400   1.000 20.08161  ? 198 VAL H HG13 1 
ATOM   2929 H HG21 . VAL A 1 202 ? 22.31867  -9.11527  5.46544   1.000 25.58456  ? 198 VAL H HG21 1 
ATOM   2930 H HG22 . VAL A 1 202 ? 22.52579  -8.54452  6.93339   1.000 25.58456  ? 198 VAL H HG22 1 
ATOM   2931 H HG23 . VAL A 1 202 ? 23.71297  -9.30595  6.20239   1.000 25.58456  ? 198 VAL H HG23 1 
ATOM   2932 N N    . ASN A 1 203 ? 21.53046  -12.23748 9.78435   1.000 15.84620  ? 199 ASN H N    1 
ATOM   2933 C CA   . ASN A 1 203 ? 21.08101  -13.51315 10.32341  1.000 19.19410  ? 199 ASN H CA   1 
ATOM   2934 C C    . ASN A 1 203 ? 19.59089  -13.63988 10.04734  1.000 19.33100  ? 199 ASN H C    1 
ATOM   2935 O O    . ASN A 1 203 ? 18.81901  -12.72159 10.35225  1.000 17.61124  ? 199 ASN H O    1 
ATOM   2936 C CB   . ASN A 1 203 ? 21.38684  -13.60656 11.82648  1.000 22.81208  ? 199 ASN H CB   1 
ATOM   2937 C CG   . ASN A 1 203 ? 21.41706  -15.03751 12.33989  1.000 29.05833  ? 199 ASN H CG   1 
ATOM   2938 O OD1  . ASN A 1 203 ? 21.24428  -15.99294 11.58505  1.000 31.53773  ? 199 ASN H OD1  1 
ATOM   2939 N ND2  . ASN A 1 203 ? 21.65837  -15.18786 13.63709  1.000 39.25350  ? 199 ASN H ND2  1 
ATOM   2940 H H    . ASN A 1 203 ? 21.12162  -11.55802 10.11719  1.000 19.02227  ? 199 ASN H H    1 
ATOM   2941 H HA   . ASN A 1 203 ? 21.53407  -14.25387 9.89099   1.000 23.03976  ? 199 ASN H HA   1 
ATOM   2942 H HB2  . ASN A 1 203 ? 22.25551  -13.20981 11.99645  1.000 27.38133  ? 199 ASN H HB2  1 
ATOM   2943 H HB3  . ASN A 1 203 ? 20.70137  -13.12734 12.31779  1.000 27.38133  ? 199 ASN H HB3  1 
ATOM   2944 H HD21 . ASN A 1 203 ? 21.68669  -15.97572 13.98072  1.000 47.11103  ? 199 ASN H HD21 1 
ATOM   2945 H HD22 . ASN A 1 203 ? 21.78633  -14.49737 14.13353  1.000 47.11103  ? 199 ASN H HD22 1 
ATOM   2946 N N    . HIS A 1 204 ? 19.19547  -14.75809 9.44230   1.000 18.26443  ? 200 HIS H N    1 
ATOM   2947 C CA   . HIS A 1 204 ? 17.79683  -15.10798 9.19609   1.000 18.03080  ? 200 HIS H CA   1 
ATOM   2948 C C    . HIS A 1 204 ? 17.58137  -16.46269 9.86475   1.000 17.42396  ? 200 HIS H C    1 
ATOM   2949 O O    . HIS A 1 204 ? 17.69620  -17.51920 9.22606   1.000 18.59234  ? 200 HIS H O    1 
ATOM   2950 C CB   . HIS A 1 204 ? 17.49388  -15.14767 7.71655   1.000 20.17485  ? 200 HIS H CB   1 
ATOM   2951 C CG   . HIS A 1 204 ? 16.05289  -15.40183 7.39296   1.000 18.09428  ? 200 HIS H CG   1 
ATOM   2952 N ND1  . HIS A 1 204 ? 15.65796  -16.38040 6.50721   1.000 21.84888  ? 200 HIS H ND1  1 
ATOM   2953 C CD2  . HIS A 1 204 ? 14.91629  -14.80648 7.82716   1.000 19.16520  ? 200 HIS H CD2  1 
ATOM   2954 C CE1  . HIS A 1 204 ? 14.34080  -16.37382 6.40384   1.000 21.11271  ? 200 HIS H CE1  1 
ATOM   2955 N NE2  . HIS A 1 204 ? 13.86615  -15.42920 7.19545   1.000 19.95180  ? 200 HIS H NE2  1 
ATOM   2956 H H    . HIS A 1 204 ? 19.74266  -15.35518 9.15306   1.000 21.92415  ? 200 HIS H H    1 
ATOM   2957 H HA   . HIS A 1 204 ? 17.20816  -14.44612 9.59144   1.000 21.64380  ? 200 HIS H HA   1 
ATOM   2958 H HB2  . HIS A 1 204 ? 17.73695  -14.29330 7.32686   1.000 24.21666  ? 200 HIS H HB2  1 
ATOM   2959 H HB3  . HIS A 1 204 ? 18.01628  -15.85764 7.31163   1.000 24.21666  ? 200 HIS H HB3  1 
ATOM   2960 H HD2  . HIS A 1 204 ? 14.85745  -14.10766 8.43796   1.000 23.00508  ? 200 HIS H HD2  1 
ATOM   2961 H HE1  . HIS A 1 204 ? 13.83427  -16.93814 5.86544   1.000 25.34208  ? 200 HIS H HE1  1 
ATOM   2962 H HE2  . HIS A 1 204 ? 13.03475  -15.23512 7.29895   1.000 23.94899  ? 200 HIS H HE2  1 
ATOM   2963 N N    . LYS A 1 205 ? 17.30895  -16.42340 11.16955  1.000 20.13689  ? 201 LYS H N    1 
ATOM   2964 C CA   . LYS A 1 205 ? 17.14560  -17.65874 11.92475  1.000 20.62475  ? 201 LYS H CA   1 
ATOM   2965 C C    . LYS A 1 205 ? 15.95790  -18.49062 11.45645  1.000 21.51316  ? 201 LYS H C    1 
ATOM   2966 O O    . LYS A 1 205 ? 16.06231  -19.72872 11.49549  1.000 19.46205  ? 201 LYS H O    1 
ATOM   2967 C CB   . LYS A 1 205 ? 17.02284  -17.34044 13.42183  1.000 25.19468  ? 201 LYS H CB   1 
ATOM   2968 C CG   . LYS A 1 205 ? 18.20223  -16.55792 13.98226  1.000 30.46468  ? 201 LYS H CG   1 
ATOM   2969 C CD   . LYS A 1 205 ? 18.62911  -17.06862 15.35900  1.000 47.33053  ? 201 LYS H CD   1 
ATOM   2970 C CE   . LYS A 1 205 ? 19.60953  -16.11498 16.04785  1.000 44.45413  ? 201 LYS H CE   1 
ATOM   2971 N NZ   . LYS A 1 205 ? 19.26537  -15.90627 17.48586  1.000 45.08254  ? 201 LYS H NZ   1 
ATOM   2972 H H    . LYS A 1 205 ? 17.21544  -15.70480 11.63266  1.000 24.17110  ? 201 LYS H H    1 
ATOM   2973 H HA   . LYS A 1 205 ? 17.94577  -18.19279 11.80061  1.000 24.75653  ? 201 LYS H HA   1 
ATOM   2974 H HB2  . LYS A 1 205 ? 16.22241  -16.81109 13.56325  1.000 30.24045  ? 201 LYS H HB2  1 
ATOM   2975 H HB3  . LYS A 1 205 ? 16.96036  -18.17421 13.91358  1.000 30.24045  ? 201 LYS H HB3  1 
ATOM   2976 H HG2  . LYS A 1 205 ? 18.95769  -16.64454 13.38004  1.000 36.56445  ? 201 LYS H HG2  1 
ATOM   2977 H HG3  . LYS A 1 205 ? 17.95312  -15.62455 14.06989  1.000 36.56445  ? 201 LYS H HG3  1 
ATOM   2978 H HD2  . LYS A 1 205 ? 17.84545  -17.15662 15.92382  1.000 56.80347  ? 201 LYS H HD2  1 
ATOM   2979 H HD3  . LYS A 1 205 ? 19.06443  -17.92967 15.25909  1.000 56.80347  ? 201 LYS H HD3  1 
ATOM   2980 H HE2  . LYS A 1 205 ? 20.50400  -16.48729 16.00087  1.000 53.35179  ? 201 LYS H HE2  1 
ATOM   2981 H HE3  . LYS A 1 205 ? 19.58471  -15.25396 15.60185  1.000 53.35179  ? 201 LYS H HE3  1 
ATOM   2982 H HZ1  . LYS A 1 205 ? 19.85457  -15.35618 17.86313  1.000 54.10589  ? 201 LYS H HZ1  1 
ATOM   2983 H HZ2  . LYS A 1 205 ? 18.45243  -15.55081 17.55581  1.000 54.10589  ? 201 LYS H HZ2  1 
ATOM   2984 H HZ3  . LYS A 1 205 ? 19.27862  -16.68418 17.91804  1.000 54.10589  ? 201 LYS H HZ3  1 
ATOM   2985 N N    . PRO A 1 206 ? 14.84143  -17.91282 11.01369  1.000 22.92901  ? 202 PRO H N    1 
ATOM   2986 C CA   . PRO A 1 206 ? 13.75440  -18.75217 10.48746  1.000 21.42091  ? 202 PRO H CA   1 
ATOM   2987 C C    . PRO A 1 206 ? 14.19077  -19.70939 9.39131   1.000 22.56984  ? 202 PRO H C    1 
ATOM   2988 O O    . PRO A 1 206 ? 13.62398  -20.80383 9.29523   1.000 25.35767  ? 202 PRO H O    1 
ATOM   2989 C CB   . PRO A 1 206 ? 12.74334  -17.71967 9.97258   1.000 24.60534  ? 202 PRO H CB   1 
ATOM   2990 C CG   . PRO A 1 206 ? 12.96834  -16.52003 10.81990  1.000 23.46351  ? 202 PRO H CG   1 
ATOM   2991 C CD   . PRO A 1 206 ? 14.44690  -16.49577 11.11153  1.000 21.93575  ? 202 PRO H CD   1 
ATOM   2992 H HA   . PRO A 1 206 ? 13.35516  -19.26286 11.20906  1.000 25.71192  ? 202 PRO H HA   1 
ATOM   2993 H HB2  . PRO A 1 206 ? 12.91576  -17.52385 9.03833   1.000 29.53324  ? 202 PRO H HB2  1 
ATOM   2994 H HB3  . PRO A 1 206 ? 11.84043  -18.05760 10.07957  1.000 29.53324  ? 202 PRO H HB3  1 
ATOM   2995 H HG2  . PRO A 1 206 ? 12.70007  -15.72286 10.33672  1.000 28.16304  ? 202 PRO H HG2  1 
ATOM   2996 H HG3  . PRO A 1 206 ? 12.45726  -16.59827 11.64061  1.000 28.16304  ? 202 PRO H HG3  1 
ATOM   2997 H HD2  . PRO A 1 206 ? 14.91873  -15.96085 10.45416  1.000 26.32973  ? 202 PRO H HD2  1 
ATOM   2998 H HD3  . PRO A 1 206 ? 14.61645  -16.15192 12.00256  1.000 26.32973  ? 202 PRO H HD3  1 
ATOM   2999 N N    . SER A 1 207 ? 15.16961  -19.33840 8.55692   1.000 19.68775  ? 203 SER H N    1 
ATOM   3000 C CA   . SER A 1 207 ? 15.70489  -20.22171 7.52553   1.000 22.95843  ? 203 SER H CA   1 
ATOM   3001 C C    . SER A 1 207 ? 17.04095  -20.84499 7.90793   1.000 20.84180  ? 203 SER H C    1 
ATOM   3002 O O    . SER A 1 207 ? 17.63002  -21.55928 7.09067   1.000 19.27649  ? 203 SER H O    1 
ATOM   3003 C CB   . SER A 1 207 ? 15.88215  -19.47003 6.19673   1.000 27.15100  ? 203 SER H CB   1 
ATOM   3004 O OG   . SER A 1 207 ? 16.95464  -18.54269 6.26021   1.000 22.97111  ? 203 SER H OG   1 
ATOM   3005 H H    . SER A 1 207 ? 15.54388  -18.56427 8.57265   1.000 23.63214  ? 203 SER H H    1 
ATOM   3006 H HA   . SER A 1 207 ? 15.05858  -20.93176 7.38770   1.000 27.55695  ? 203 SER H HA   1 
ATOM   3007 H HB2  . SER A 1 207 ? 16.06670  -20.11409 5.49529   1.000 32.58804  ? 203 SER H HB2  1 
ATOM   3008 H HB3  . SER A 1 207 ? 15.06379  -18.98862 5.99817   1.000 32.58804  ? 203 SER H HB3  1 
ATOM   3009 H HG   . SER A 1 207 ? 17.06955  -18.18448 5.50915   1.000 27.57216  ? 203 SER H HG   1 
ATOM   3010 N N    . ASN A 1 208 ? 17.53237  -20.58824 9.11527   1.000 19.85134  ? 204 ASN H N    1 
ATOM   3011 C CA   . ASN A 1 208 ? 18.87332  -21.00811 9.51512   1.000 20.78776  ? 204 ASN H CA   1 
ATOM   3012 C C    . ASN A 1 208 ? 19.91005  -20.57435 8.48373   1.000 22.44862  ? 204 ASN H C    1 
ATOM   3013 O O    . ASN A 1 208 ? 20.80348  -21.33807 8.10799   1.000 20.91030  ? 204 ASN H O    1 
ATOM   3014 C CB   . ASN A 1 208 ? 18.92182  -22.51863 9.74086   1.000 26.11369  ? 204 ASN H CB   1 
ATOM   3015 C CG   . ASN A 1 208 ? 18.16236  -22.93557 10.97721  1.000 24.40889  ? 204 ASN H CG   1 
ATOM   3016 O OD1  . ASN A 1 208 ? 18.36524  -22.37944 12.05067  1.000 29.10206  ? 204 ASN H OD1  1 
ATOM   3017 N ND2  . ASN A 1 208 ? 17.26734  -23.89884 10.82858  1.000 29.27493  ? 204 ASN H ND2  1 
ATOM   3018 H H    . ASN A 1 208 ? 17.10379  -20.16656 9.73018   1.000 23.82844  ? 204 ASN H H    1 
ATOM   3019 H HA   . ASN A 1 208 ? 19.09773  -20.57341 10.35272  1.000 24.95215  ? 204 ASN H HA   1 
ATOM   3020 H HB2  . ASN A 1 208 ? 18.52605  -22.96733 8.97736   1.000 31.34326  ? 204 ASN H HB2  1 
ATOM   3021 H HB3  . ASN A 1 208 ? 19.84561  -22.79515 9.84600   1.000 31.34326  ? 204 ASN H HB3  1 
ATOM   3022 H HD21 . ASN A 1 208 ? 16.81047  -24.16942 11.50509  1.000 35.13675  ? 204 ASN H HD21 1 
ATOM   3023 H HD22 . ASN A 1 208 ? 17.14253  -24.25429 10.05549  1.000 35.13675  ? 204 ASN H HD22 1 
ATOM   3024 N N    . THR A 1 209 ? 19.78912  -19.33253 8.01487   1.000 23.11018  ? 205 THR H N    1 
ATOM   3025 C CA   . THR A 1 209 ? 20.72400  -18.78385 7.03757   1.000 18.74587  ? 205 THR H CA   1 
ATOM   3026 C C    . THR A 1 209 ? 21.46973  -17.60959 7.65722   1.000 19.95747  ? 205 THR H C    1 
ATOM   3027 O O    . THR A 1 209 ? 20.88703  -16.81033 8.39022   1.000 18.43759  ? 205 THR H O    1 
ATOM   3028 C CB   . THR A 1 209 ? 20.00837  -18.32572 5.75184   1.000 24.03054  ? 205 THR H CB   1 
ATOM   3029 O OG1  . THR A 1 209 ? 19.22723  -19.40147 5.21064   1.000 26.12775  ? 205 THR H OG1  1 
ATOM   3030 C CG2  . THR A 1 209 ? 21.02282  -17.88324 4.70057   1.000 23.54112  ? 205 THR H CG2  1 
ATOM   3031 H H    . THR A 1 209 ? 19.16830  -18.78621 8.25091   1.000 27.73905  ? 205 THR H H    1 
ATOM   3032 H HA   . THR A 1 209 ? 21.36538  -19.46840 6.79073   1.000 22.50188  ? 205 THR H HA   1 
ATOM   3033 H HB   . THR A 1 209 ? 19.42860  -17.57815 5.96609   1.000 28.84348  ? 205 THR H HB   1 
ATOM   3034 H HG1  . THR A 1 209 ? 18.64652  -19.64321 5.76736   1.000 31.36014  ? 205 THR H HG1  1 
ATOM   3035 H HG21 . THR A 1 209 ? 20.57179  -17.69588 3.86249   1.000 28.25617  ? 205 THR H HG21 1 
ATOM   3036 H HG22 . THR A 1 209 ? 21.48041  -17.08132 4.99794   1.000 28.25617  ? 205 THR H HG22 1 
ATOM   3037 H HG23 . THR A 1 209 ? 21.67768  -18.58403 4.55583   1.000 28.25617  ? 205 THR H HG23 1 
ATOM   3038 N N    . LYS A 1 210 ? 22.76218  -17.51474 7.37434   1.000 18.92552  ? 206 LYS H N    1 
ATOM   3039 C CA   . LYS A 1 210 ? 23.58970  -16.40963 7.83569   1.000 21.56481  ? 206 LYS H CA   1 
ATOM   3040 C C    . LYS A 1 210 ? 24.42567  -15.94309 6.65474   1.000 23.59338  ? 206 LYS H C    1 
ATOM   3041 O O    . LYS A 1 210 ? 24.93766  -16.76735 5.89461   1.000 22.09422  ? 206 LYS H O    1 
ATOM   3042 C CB   . LYS A 1 210 ? 24.47782  -16.85082 9.00397   1.000 25.27131  ? 206 LYS H CB   1 
ATOM   3043 C CG   . LYS A 1 210 ? 25.04825  -15.73801 9.84557   1.000 38.17942  ? 206 LYS H CG   1 
ATOM   3044 C CD   . LYS A 1 210 ? 26.19738  -16.25323 10.71509  1.000 49.26470  ? 206 LYS H CD   1 
ATOM   3045 C CE   . LYS A 1 210 ? 25.75309  -17.36417 11.66576  1.000 48.62506  ? 206 LYS H CE   1 
ATOM   3046 N NZ   . LYS A 1 210 ? 26.88523  -17.88152 12.50212  1.000 48.37772  ? 206 LYS H NZ   1 
ATOM   3047 H H    . LYS A 1 210 ? 23.19273  -18.09271 6.90511   1.000 22.71746  ? 206 LYS H H    1 
ATOM   3048 H HA   . LYS A 1 210 ? 23.05365  -15.66451 8.14927   1.000 25.88461  ? 206 LYS H HA   1 
ATOM   3049 H HB2  . LYS A 1 210 ? 23.95066  -17.41495 9.59113   1.000 30.33240  ? 206 LYS H HB2  1 
ATOM   3050 H HB3  . LYS A 1 210 ? 25.22597  -17.35313 8.64499   1.000 30.33240  ? 206 LYS H HB3  1 
ATOM   3051 H HG2  . LYS A 1 210 ? 25.38870  -15.03658 9.26852   1.000 45.82214  ? 206 LYS H HG2  1 
ATOM   3052 H HG3  . LYS A 1 210 ? 24.35703  -15.38345 10.42643  1.000 45.82214  ? 206 LYS H HG3  1 
ATOM   3053 H HD2  . LYS A 1 210 ? 26.89538  -16.60788 10.14244  1.000 59.12447  ? 206 LYS H HD2  1 
ATOM   3054 H HD3  . LYS A 1 210 ? 26.54559  -15.52161 11.24837  1.000 59.12447  ? 206 LYS H HD3  1 
ATOM   3055 H HE2  . LYS A 1 210 ? 25.07041  -17.01879 12.26205  1.000 58.35690  ? 206 LYS H HE2  1 
ATOM   3056 H HE3  . LYS A 1 210 ? 25.39801  -18.10339 11.14771  1.000 58.35690  ? 206 LYS H HE3  1 
ATOM   3057 H HZ1  . LYS A 1 210 ? 26.59358  -18.52275 13.04606  1.000 58.06010  ? 206 LYS H HZ1  1 
ATOM   3058 H HZ2  . LYS A 1 210 ? 27.52296  -18.21491 11.97844  1.000 58.06010  ? 206 LYS H HZ2  1 
ATOM   3059 H HZ3  . LYS A 1 210 ? 27.22855  -17.22193 12.99118  1.000 58.06010  ? 206 LYS H HZ3  1 
ATOM   3060 N N    . VAL A 1 211 ? 24.54696  -14.62861 6.48227   1.000 19.27789  ? 207 VAL H N    1 
ATOM   3061 C CA   . VAL A 1 211 ? 25.28396  -14.05152 5.36386   1.000 19.93023  ? 207 VAL H CA   1 
ATOM   3062 C C    . VAL A 1 211 ? 26.21088  -12.97745 5.90132   1.000 25.47924  ? 207 VAL H C    1 
ATOM   3063 O O    . VAL A 1 211 ? 25.79590  -12.13744 6.70215   1.000 22.19829  ? 207 VAL H O    1 
ATOM   3064 C CB   . VAL A 1 211 ? 24.34609  -13.45361 4.29681   1.000 19.10116  ? 207 VAL H CB   1 
ATOM   3065 C CG1  . VAL A 1 211 ? 25.15214  -12.90243 3.12182   1.000 22.29890  ? 207 VAL H CG1  1 
ATOM   3066 C CG2  . VAL A 1 211 ? 23.34062  -14.49048 3.82042   1.000 23.85286  ? 207 VAL H CG2  1 
ATOM   3067 H H    . VAL A 1 211 ? 24.20454  -14.04222 7.01000   1.000 23.14031  ? 207 VAL H H    1 
ATOM   3068 H HA   . VAL A 1 211 ? 25.81863  -14.74677 4.94954   1.000 23.92311  ? 207 VAL H HA   1 
ATOM   3069 H HB   . VAL A 1 211 ? 23.85188  -12.71963 4.69424   1.000 22.92822  ? 207 VAL H HB   1 
ATOM   3070 H HG11 . VAL A 1 211 ? 24.54505  -12.68204 2.39810   1.000 26.76551  ? 207 VAL H HG11 1 
ATOM   3071 H HG12 . VAL A 1 211 ? 25.62629  -12.10669 3.40974   1.000 26.76551  ? 207 VAL H HG12 1 
ATOM   3072 H HG13 . VAL A 1 211 ? 25.78494  -13.57675 2.82898   1.000 26.76551  ? 207 VAL H HG13 1 
ATOM   3073 H HG21 . VAL A 1 211 ? 22.80328  -14.10627 3.11011   1.000 28.63026  ? 207 VAL H HG21 1 
ATOM   3074 H HG22 . VAL A 1 211 ? 23.81974  -15.26646 3.48995   1.000 28.63026  ? 207 VAL H HG22 1 
ATOM   3075 H HG23 . VAL A 1 211 ? 22.77251  -14.74462 4.56444   1.000 28.63026  ? 207 VAL H HG23 1 
ATOM   3076 N N    . ASP A 1 212 ? 27.45825  -12.99389 5.45581   1.000 19.55899  ? 208 ASP H N    1 
ATOM   3077 C CA   . ASP A 1 212 ? 28.40382  -11.92529 5.74743   1.000 19.78849  ? 208 ASP H CA   1 
ATOM   3078 C C    . ASP A 1 212 ? 28.83910  -11.33445 4.41820   1.000 23.73288  ? 208 ASP H C    1 
ATOM   3079 O O    . ASP A 1 212 ? 29.31466  -12.06287 3.54143   1.000 23.79489  ? 208 ASP H O    1 
ATOM   3080 C CB   . ASP A 1 212 ? 29.58393  -12.45882 6.55375   1.000 26.42986  ? 208 ASP H CB   1 
ATOM   3081 C CG   . ASP A 1 212 ? 29.14430  -13.07208 7.87567   1.000 39.35459  ? 208 ASP H CG   1 
ATOM   3082 O OD1  . ASP A 1 212 ? 28.60472  -12.33019 8.72641   1.000 35.68613  ? 208 ASP H OD1  1 
ATOM   3083 O OD2  . ASP A 1 212 ? 29.30277  -14.30034 8.04838   1.000 46.32951  ? 208 ASP H OD2  1 
ATOM   3084 H H    . ASP A 1 212 ? 27.78712  -13.62528 4.97332   1.000 23.47762  ? 208 ASP H H    1 
ATOM   3085 H HA   . ASP A 1 212 ? 27.99177  -11.22175 6.27292   1.000 23.75303  ? 208 ASP H HA   1 
ATOM   3086 H HB2  . ASP A 1 212 ? 30.03810  -13.14379 6.03854   1.000 31.72266  ? 208 ASP H HB2  1 
ATOM   3087 H HB3  . ASP A 1 212 ? 30.19381  -11.72955 6.74642   1.000 31.72266  ? 208 ASP H HB3  1 
ATOM   3088 N N    . LYS A 1 213 ? 28.63466  -10.03065 4.25297   1.000 21.74902  ? 209 LYS H N    1 
ATOM   3089 C CA   . LYS A 1 213 ? 28.90473  -9.34980  2.99188   1.000 21.55400  ? 209 LYS H CA   1 
ATOM   3090 C C    . LYS A 1 213 ? 29.87494  -8.20535  3.23366   1.000 22.70004  ? 209 LYS H C    1 
ATOM   3091 O O    . LYS A 1 213 ? 29.58123  -7.29276  4.01279   1.000 18.65920  ? 209 LYS H O    1 
ATOM   3092 C CB   . LYS A 1 213 ? 27.61430  -8.82374  2.36293   1.000 21.99352  ? 209 LYS H CB   1 
ATOM   3093 C CG   . LYS A 1 213 ? 27.81405  -8.10886  1.03259   1.000 25.30759  ? 209 LYS H CG   1 
ATOM   3094 C CD   . LYS A 1 213 ? 28.23804  -9.07299  -0.05421  1.000 28.54105  ? 209 LYS H CD   1 
ATOM   3095 C CE   . LYS A 1 213 ? 28.60516  -8.33770  -1.32764  1.000 44.68697  ? 209 LYS H CE   1 
ATOM   3096 N NZ   . LYS A 1 213 ? 28.99143  -9.26887  -2.42619  1.000 51.66073  ? 209 LYS H NZ   1 
ATOM   3097 H H    . LYS A 1 213 ? 28.33448  -9.51080  4.86881   1.000 26.10566  ? 209 LYS H H    1 
ATOM   3098 H HA   . LYS A 1 213 ? 29.31972  -9.97669  2.37893   1.000 25.87164  ? 209 LYS H HA   1 
ATOM   3099 H HB2  . LYS A 1 213 ? 27.01731  -9.57239  2.20791   1.000 26.39905  ? 209 LYS H HB2  1 
ATOM   3100 H HB3  . LYS A 1 213 ? 27.20450  -8.19417  2.97662   1.000 26.39905  ? 209 LYS H HB3  1 
ATOM   3101 H HG2  . LYS A 1 213 ? 26.98060  -7.69226  0.76295   1.000 30.37594  ? 209 LYS H HG2  1 
ATOM   3102 H HG3  . LYS A 1 213 ? 28.50532  -7.43539  1.12992   1.000 30.37594  ? 209 LYS H HG3  1 
ATOM   3103 H HD2  . LYS A 1 213 ? 29.01312  -9.57423  0.24398   1.000 34.25610  ? 209 LYS H HD2  1 
ATOM   3104 H HD3  . LYS A 1 213 ? 27.50660  -9.67899  -0.25083  1.000 34.25610  ? 209 LYS H HD3  1 
ATOM   3105 H HE2  . LYS A 1 213 ? 27.84232  -7.81837  -1.62642  1.000 53.63120  ? 209 LYS H HE2  1 
ATOM   3106 H HE3  . LYS A 1 213 ? 29.35715  -7.75105  -1.15084  1.000 53.63120  ? 209 LYS H HE3  1 
ATOM   3107 H HZ1  . LYS A 1 213 ? 29.19929  -8.80682  -3.15790  1.000 61.99971  ? 209 LYS H HZ1  1 
ATOM   3108 H HZ2  . LYS A 1 213 ? 29.69636  -9.75352  -2.18066  1.000 61.99971  ? 209 LYS H HZ2  1 
ATOM   3109 H HZ3  . LYS A 1 213 ? 28.31521  -9.81659  -2.61283  1.000 61.99971  ? 209 LYS H HZ3  1 
ATOM   3110 N N    . LYS A 1 214 ? 31.02074  -8.25554  2.56327   1.000 20.99444  ? 210 LYS H N    1 
ATOM   3111 C CA   . LYS A 1 214 ? 31.96563  -7.14909  2.58055   1.000 20.76905  ? 210 LYS H CA   1 
ATOM   3112 C C    . LYS A 1 214 ? 31.51383  -6.09898  1.57365   1.000 23.26398  ? 210 LYS H C    1 
ATOM   3113 O O    . LYS A 1 214 ? 31.29311  -6.40906  0.39910   1.000 24.83760  ? 210 LYS H O    1 
ATOM   3114 C CB   . LYS A 1 214 ? 33.37095  -7.65560  2.25452   1.000 30.94792  ? 210 LYS H CB   1 
ATOM   3115 C CG   . LYS A 1 214 ? 34.46278  -6.60250  2.35068   1.000 44.70291  ? 210 LYS H CG   1 
ATOM   3116 C CD   . LYS A 1 214 ? 35.85207  -7.24119  2.31704   1.000 50.09832  ? 210 LYS H CD   1 
ATOM   3117 C CE   . LYS A 1 214 ? 36.95822  -6.19767  2.19955   1.000 68.65310  ? 210 LYS H CE   1 
ATOM   3118 N NZ   . LYS A 1 214 ? 36.99013  -5.55566  0.85575   1.000 63.15725  ? 210 LYS H NZ   1 
ATOM   3119 H H    . LYS A 1 214 ? 31.27519  -8.92514  2.08735   1.000 25.20016  ? 210 LYS H H    1 
ATOM   3120 H HA   . LYS A 1 214 ? 31.99863  -6.73959  3.45925   1.000 24.92969  ? 210 LYS H HA   1 
ATOM   3121 H HB2  . LYS A 1 214 ? 33.59451  -8.36600  2.87602   1.000 37.14434  ? 210 LYS H HB2  1 
ATOM   3122 H HB3  . LYS A 1 214 ? 33.37282  -7.99649  1.34640   1.000 37.14434  ? 210 LYS H HB3  1 
ATOM   3123 H HG2  . LYS A 1 214 ? 34.38849  -5.99166  1.60084   1.000 53.65032  ? 210 LYS H HG2  1 
ATOM   3124 H HG3  . LYS A 1 214 ? 34.36944  -6.11655  3.18497   1.000 53.65032  ? 210 LYS H HG3  1 
ATOM   3125 H HD2  . LYS A 1 214 ? 35.99353  -7.74137  3.13601   1.000 60.12481  ? 210 LYS H HD2  1 
ATOM   3126 H HD3  . LYS A 1 214 ? 35.91260  -7.83396  1.55162   1.000 60.12481  ? 210 LYS H HD3  1 
ATOM   3127 H HE2  . LYS A 1 214 ? 36.81259  -5.50401  2.86176   1.000 82.39055  ? 210 LYS H HE2  1 
ATOM   3128 H HE3  . LYS A 1 214 ? 37.81587  -6.62513  2.34997   1.000 82.39055  ? 210 LYS H HE3  1 
ATOM   3129 H HZ1  . LYS A 1 214 ? 36.72586  -4.70801  0.91702   1.000 75.79553  ? 210 LYS H HZ1  1 
ATOM   3130 H HZ2  . LYS A 1 214 ? 37.81714  -5.57737  0.52759   1.000 75.79553  ? 210 LYS H HZ2  1 
ATOM   3131 H HZ3  . LYS A 1 214 ? 36.44697  -5.98802  0.29886   1.000 75.79553  ? 210 LYS H HZ3  1 
ATOM   3132 N N    . VAL A 1 215 ? 31.35162  -4.86442  2.03847   1.000 19.25554  ? 211 VAL H N    1 
ATOM   3133 C CA   . VAL A 1 215 ? 30.87533  -3.76395  1.21189   1.000 19.50697  ? 211 VAL H CA   1 
ATOM   3134 C C    . VAL A 1 215 ? 32.09316  -2.93914  0.81468   1.000 30.49712  ? 211 VAL H C    1 
ATOM   3135 O O    . VAL A 1 215 ? 32.69308  -2.25420  1.65032   1.000 24.58471  ? 211 VAL H O    1 
ATOM   3136 C CB   . VAL A 1 215 ? 29.82769  -2.92099  1.94843   1.000 19.16932  ? 211 VAL H CB   1 
ATOM   3137 C CG1  . VAL A 1 215 ? 29.37604  -1.75866  1.09007   1.000 23.96546  ? 211 VAL H CG1  1 
ATOM   3138 C CG2  . VAL A 1 215 ? 28.62112  -3.79123  2.33284   1.000 22.41641  ? 211 VAL H CG2  1 
ATOM   3139 H H    . VAL A 1 215 ? 31.51561  -4.63516  2.85097   1.000 23.11348  ? 211 VAL H H    1 
ATOM   3140 H HA   . VAL A 1 215 ? 30.46557  -4.11120  0.40417   1.000 23.41520  ? 211 VAL H HA   1 
ATOM   3141 H HB   . VAL A 1 215 ? 30.22750  -2.56512  2.75738   1.000 23.01001  ? 211 VAL H HB   1 
ATOM   3142 H HG11 . VAL A 1 215 ? 28.60767  -1.33815  1.50682   1.000 28.76539  ? 211 VAL H HG11 1 
ATOM   3143 H HG12 . VAL A 1 215 ? 30.10250  -1.12024  1.01536   1.000 28.76539  ? 211 VAL H HG12 1 
ATOM   3144 H HG13 . VAL A 1 215 ? 29.13531  -2.09018  0.21084   1.000 28.76539  ? 211 VAL H HG13 1 
ATOM   3145 H HG21 . VAL A 1 215 ? 27.95655  -3.23495  2.76851   1.000 26.90652  ? 211 VAL H HG21 1 
ATOM   3146 H HG22 . VAL A 1 215 ? 28.24721  -4.18537  1.52926   1.000 26.90652  ? 211 VAL H HG22 1 
ATOM   3147 H HG23 . VAL A 1 215 ? 28.91565  -4.48994  2.93779   1.000 26.90652  ? 211 VAL H HG23 1 
ATOM   3148 N N    . GLU A 1 216 ? 32.46514  -3.01820  -0.46355  1.000 29.59014  ? 212 GLU H N    1 
ATOM   3149 C CA   . GLU A 1 216 ? 33.64722  -2.38216  -1.01579  1.000 34.87880  ? 212 GLU H CA   1 
ATOM   3150 C C    . GLU A 1 216 ? 33.27434  -1.13435  -1.80467  1.000 36.25703  ? 212 GLU H C    1 
ATOM   3151 O O    . GLU A 1 216 ? 32.16170  -1.03092  -2.32896  1.000 35.13874  ? 212 GLU H O    1 
ATOM   3152 C CB   . GLU A 1 216 ? 34.39131  -3.34200  -1.94710  1.000 40.31572  ? 212 GLU H CB   1 
ATOM   3153 C CG   . GLU A 1 216 ? 34.78911  -4.65057  -1.30570  1.000 44.68035  ? 212 GLU H CG   1 
ATOM   3154 C CD   . GLU A 1 216 ? 35.68675  -5.48437  -2.20113  1.000 52.84814  ? 212 GLU H CD   1 
ATOM   3155 O OE1  . GLU A 1 216 ? 35.26944  -5.80732  -3.33710  1.000 42.66504  ? 212 GLU H OE1  1 
ATOM   3156 O OE2  . GLU A 1 216 ? 36.81568  -5.80568  -1.76885  1.000 52.02131  ? 212 GLU H OE2  1 
ATOM   3157 H H    . GLU A 1 216 ? 32.02401  -3.45763  -1.05676  1.000 35.51500  ? 212 GLU H H    1 
ATOM   3158 H HA   . GLU A 1 216 ? 34.24020  -2.12819  -0.29138  1.000 41.86139  ? 212 GLU H HA   1 
ATOM   3159 H HB2  . GLU A 1 216 ? 33.81774  -3.54756  -2.70186  1.000 48.38570  ? 212 GLU H HB2  1 
ATOM   3160 H HB3  . GLU A 1 216 ? 35.20213  -2.90776  -2.25517  1.000 48.38570  ? 212 GLU H HB3  1 
ATOM   3161 H HG2  . GLU A 1 216 ? 35.26979  -4.46777  -0.48325  1.000 53.62325  ? 212 GLU H HG2  1 
ATOM   3162 H HG3  . GLU A 1 216 ? 33.99013  -5.16660  -1.11533  1.000 53.62325  ? 212 GLU H HG3  1 
ATOM   3163 N N    . PRO A 1 217 ? 34.19120  -0.17847  -1.92371  1.000 38.84092  ? 213 PRO H N    1 
ATOM   3164 C CA   . PRO A 1 217 ? 33.93218  0.97362   -2.79132  1.000 44.60186  ? 213 PRO H CA   1 
ATOM   3165 C C    . PRO A 1 217 ? 33.80821  0.55058   -4.24650  1.000 46.94350  ? 213 PRO H C    1 
ATOM   3166 O O    . PRO A 1 217 ? 34.31885  -0.48952  -4.66840  1.000 46.96494  ? 213 PRO H O    1 
ATOM   3167 C CB   . PRO A 1 217 ? 35.15797  1.87150   -2.57650  1.000 50.61956  ? 213 PRO H CB   1 
ATOM   3168 C CG   . PRO A 1 217 ? 35.76329  1.41129   -1.29461  1.000 38.39804  ? 213 PRO H CG   1 
ATOM   3169 C CD   . PRO A 1 217 ? 35.47974  -0.05891  -1.22382  1.000 37.95123  ? 213 PRO H CD   1 
ATOM   3170 H HA   . PRO A 1 217 ? 33.13062  1.44357   -2.51284  1.000 53.52907  ? 213 PRO H HA   1 
ATOM   3171 H HB2  . PRO A 1 217 ? 35.78004  1.76036   -3.31242  1.000 60.75030  ? 213 PRO H HB2  1 
ATOM   3172 H HB3  . PRO A 1 217 ? 34.87966  2.79865   -2.51449  1.000 60.75030  ? 213 PRO H HB3  1 
ATOM   3173 H HG2  . PRO A 1 217 ? 36.71877  1.57828   -1.30362  1.000 46.08448  ? 213 PRO H HG2  1 
ATOM   3174 H HG3  . PRO A 1 217 ? 35.35191  1.87817   -0.55051  1.000 46.08448  ? 213 PRO H HG3  1 
ATOM   3175 H HD2  . PRO A 1 217 ? 36.16963  -0.56743  -1.67809  1.000 45.54831  ? 213 PRO H HD2  1 
ATOM   3176 H HD3  . PRO A 1 217 ? 35.40275  -0.35330  -0.30279  1.000 45.54831  ? 213 PRO H HD3  1 
ATOM   3177 N N    . LYS A 1 218 ? 33.10513  1.37753   -5.01354  1.000 60.98158  ? 214 LYS H N    1 
ATOM   3178 C CA   . LYS A 1 218 ? 32.94647  1.16219   -6.44852  1.000 65.62501  ? 214 LYS H CA   1 
ATOM   3179 C C    . LYS A 1 218 ? 32.14779  -0.10731  -6.71661  1.000 59.53381  ? 214 LYS H C    1 
ATOM   3180 O O    . LYS A 1 218 ? 31.52607  -0.24748  -7.77065  1.000 56.58463  ? 214 LYS H O    1 
ATOM   3181 C CB   . LYS A 1 218 ? 34.31985  1.09401   -7.13418  1.000 56.30095  ? 214 LYS H CB   1 
ATOM   3182 C CG   . LYS A 1 218 ? 34.28018  0.79608   -8.63151  1.000 73.49029  ? 214 LYS H CG   1 
ATOM   3183 C CD   . LYS A 1 218 ? 34.39018  -0.69901  -8.94537  1.000 73.20240  ? 214 LYS H CD   1 
ATOM   3184 C CE   . LYS A 1 218 ? 35.75260  -1.27381  -8.57650  1.000 71.01983  ? 214 LYS H CE   1 
ATOM   3185 N NZ   . LYS A 1 218 ? 36.86237  -0.58480  -9.28308  1.000 64.69934  ? 214 LYS H NZ   1 
ATOM   3186 H H    . LYS A 1 218 ? 32.70424  2.08083   -4.72327  1.000 73.18473  ? 214 LYS H H    1 
ATOM   3187 H HA   . LYS A 1 218 ? 32.46078  1.90679   -6.83656  1.000 78.75685  ? 214 LYS H HA   1 
ATOM   3188 H HB2  . LYS A 1 218 ? 34.76287  1.94928   -7.01955  1.000 67.56797  ? 214 LYS H HB2  1 
ATOM   3189 H HB3  . LYS A 1 218 ? 34.83924  0.39209   -6.71174  1.000 67.56797  ? 214 LYS H HB3  1 
ATOM   3190 H HG2  . LYS A 1 218 ? 33.44007  1.11676   -8.99523  1.000 88.19518  ? 214 LYS H HG2  1 
ATOM   3191 H HG3  . LYS A 1 218 ? 35.02239  1.24743   -9.06315  1.000 88.19518  ? 214 LYS H HG3  1 
ATOM   3192 H HD2  . LYS A 1 218 ? 33.71477  -1.17966  -8.44169  1.000 87.84971  ? 214 LYS H HD2  1 
ATOM   3193 H HD3  . LYS A 1 218 ? 34.25413  -0.83464  -9.89616  1.000 87.84971  ? 214 LYS H HD3  1 
ATOM   3194 H HE2  . LYS A 1 218 ? 35.89314  -1.17252  -7.62209  1.000 85.23063  ? 214 LYS H HE2  1 
ATOM   3195 H HE3  . LYS A 1 218 ? 35.77788  -2.21300  -8.81773  1.000 85.23063  ? 214 LYS H HE3  1 
ATOM   3196 H HZ1  . LYS A 1 218 ? 37.63683  -0.97897  -9.09088  1.000 77.64604  ? 214 LYS H HZ1  1 
ATOM   3197 H HZ2  . LYS A 1 218 ? 36.73115  -0.61936  -10.16268 1.000 77.64604  ? 214 LYS H HZ2  1 
ATOM   3198 H HZ3  . LYS A 1 218 ? 36.90152  0.26761   -9.03017  1.000 77.64604  ? 214 LYS H HZ3  1 
ATOM   3199 N N    . ASP B 2 1   ? -15.63938 -8.46178  30.85509  1.000 61.07608  ? 1   ASP L N    1 
ATOM   3200 C CA   . ASP B 2 1   ? -14.51035 -8.15938  29.92428  1.000 63.90126  ? 1   ASP L CA   1 
ATOM   3201 C C    . ASP B 2 1   ? -13.78323 -6.88988  30.36193  1.000 50.78629  ? 1   ASP L C    1 
ATOM   3202 O O    . ASP B 2 1   ? -14.24365 -5.77714  30.10064  1.000 53.99257  ? 1   ASP L O    1 
ATOM   3203 C CB   . ASP B 2 1   ? -15.02521 -8.01861  28.48968  1.000 74.67901  ? 1   ASP L CB   1 
ATOM   3204 C CG   . ASP B 2 1   ? -15.22318 -9.36469  27.80338  1.000 91.57367  ? 1   ASP L CG   1 
ATOM   3205 O OD1  . ASP B 2 1   ? -14.21604 -10.06755 27.56854  1.000 91.36984  ? 1   ASP L OD1  1 
ATOM   3206 O OD2  . ASP B 2 1   ? -16.38386 -9.72666  27.50751  1.000 71.35380  ? 1   ASP L OD2  1 
ATOM   3207 H H1   . ASP B 2 1   ? -16.05440 -9.20217  30.58736  1.000 73.29813  ? 1   ASP L H1   1 
ATOM   3208 H H2   . ASP B 2 1   ? -15.32173 -8.58074  31.67792  1.000 73.29813  ? 1   ASP L H2   1 
ATOM   3209 H H3   . ASP B 2 1   ? -16.21446 -7.78253  30.85440  1.000 73.29813  ? 1   ASP L H3   1 
ATOM   3210 H HA   . ASP B 2 1   ? -13.87274 -8.89027  29.93659  1.000 76.68835  ? 1   ASP L HA   1 
ATOM   3211 H HB2  . ASP B 2 1   ? -15.87971 -7.55978  28.50353  1.000 89.62165  ? 1   ASP L HB2  1 
ATOM   3212 H HB3  . ASP B 2 1   ? -14.38315 -7.50861  27.97146  1.000 89.62165  ? 1   ASP L HB3  1 
ATOM   3213 N N    . ILE B 2 2   ? -12.63668 -7.07256  31.01922  1.000 38.34839  ? 2   ILE L N    1 
ATOM   3214 C CA   . ILE B 2 2   ? -11.93821 -5.96045  31.65363  1.000 41.62381  ? 2   ILE L CA   1 
ATOM   3215 C C    . ILE B 2 2   ? -11.33358 -5.05658  30.58959  1.000 42.01922  ? 2   ILE L C    1 
ATOM   3216 O O    . ILE B 2 2   ? -10.64502 -5.51727  29.66985  1.000 37.92882  ? 2   ILE L O    1 
ATOM   3217 C CB   . ILE B 2 2   ? -10.85457 -6.47752  32.61099  1.000 33.26608  ? 2   ILE L CB   1 
ATOM   3218 C CG1  . ILE B 2 2   ? -11.47175 -7.38232  33.68514  1.000 36.47637  ? 2   ILE L CG1  1 
ATOM   3219 C CG2  . ILE B 2 2   ? -10.14564 -5.31156  33.25559  1.000 32.38392  ? 2   ILE L CG2  1 
ATOM   3220 C CD1  . ILE B 2 2   ? -10.47185 -8.32693  34.34697  1.000 39.06250  ? 2   ILE L CD1  1 
ATOM   3221 H H    . ILE B 2 2   ? -12.24382 -7.83204  31.11114  1.000 46.02490  ? 2   ILE L H    1 
ATOM   3222 H HA   . ILE B 2 2   ? -12.58138 -5.44424  32.16428  1.000 49.95541  ? 2   ILE L HA   1 
ATOM   3223 H HB   . ILE B 2 2   ? -10.21504 -7.00006  32.10222  1.000 39.92613  ? 2   ILE L HB   1 
ATOM   3224 H HG12 . ILE B 2 2   ? -11.85520 -6.82416  34.37964  1.000 43.77847  ? 2   ILE L HG12 1 
ATOM   3225 H HG13 . ILE B 2 2   ? -12.16386 -7.92454  33.27541  1.000 43.77847  ? 2   ILE L HG13 1 
ATOM   3226 H HG21 . ILE B 2 2   ? -9.63561  -5.63303  34.01548  1.000 38.86753  ? 2   ILE L HG21 1 
ATOM   3227 H HG22 . ILE B 2 2   ? -9.55080  -4.90533  32.60595  1.000 38.86753  ? 2   ILE L HG22 1 
ATOM   3228 H HG23 . ILE B 2 2   ? -10.80547 -4.66438  33.55000  1.000 38.86753  ? 2   ILE L HG23 1 
ATOM   3229 H HD11 . ILE B 2 2   ? -10.93710 -8.87133  35.00124  1.000 46.88184  ? 2   ILE L HD11 1 
ATOM   3230 H HD12 . ILE B 2 2   ? -10.07516 -8.89371  33.66705  1.000 46.88184  ? 2   ILE L HD12 1 
ATOM   3231 H HD13 . ILE B 2 2   ? -9.78271  -7.80202  34.78338  1.000 46.88184  ? 2   ILE L HD13 1 
ATOM   3232 N N    . GLN B 2 3   ? -11.56771 -3.76004  30.72374  1.000 35.65970  ? 3   GLN L N    1 
ATOM   3233 C CA   . GLN B 2 3   ? -11.09078 -2.78950  29.75675  1.000 34.74163  ? 3   GLN L CA   1 
ATOM   3234 C C    . GLN B 2 3   ? -10.27878 -1.72482  30.47677  1.000 30.92093  ? 3   GLN L C    1 
ATOM   3235 O O    . GLN B 2 3   ? -10.65907 -1.24879  31.55125  1.000 25.04140  ? 3   GLN L O    1 
ATOM   3236 C CB   . GLN B 2 3   ? -12.25797 -2.14510  28.99175  1.000 40.96481  ? 3   GLN L CB   1 
ATOM   3237 C CG   . GLN B 2 3   ? -13.17621 -3.14470  28.28908  1.000 45.62496  ? 3   GLN L CG   1 
ATOM   3238 C CD   . GLN B 2 3   ? -12.60450 -3.64518  26.97844  1.000 60.21485  ? 3   GLN L CD   1 
ATOM   3239 O OE1  . GLN B 2 3   ? -12.44856 -2.87734  26.02604  1.000 57.66318  ? 3   GLN L OE1  1 
ATOM   3240 N NE2  . GLN B 2 3   ? -12.28629 -4.93852  26.92096  1.000 56.87205  ? 3   GLN L NE2  1 
ATOM   3241 H H    . GLN B 2 3   ? -12.00749 -3.41472  31.37716  1.000 42.79847  ? 3   GLN L H    1 
ATOM   3242 H HA   . GLN B 2 3   ? -10.51389 -3.22360  29.10895  1.000 41.69679  ? 3   GLN L HA   1 
ATOM   3243 H HB2  . GLN B 2 3   ? -12.79849 -1.64010  29.61921  1.000 49.16460  ? 3   GLN L HB2  1 
ATOM   3244 H HB3  . GLN B 2 3   ? -11.89524 -1.55278  28.31464  1.000 49.16460  ? 3   GLN L HB3  1 
ATOM   3245 H HG2  . GLN B 2 3   ? -13.31226 -3.91045  28.86876  1.000 54.75678  ? 3   GLN L HG2  1 
ATOM   3246 H HG3  . GLN B 2 3   ? -14.02566 -2.71566  28.10133  1.000 54.75678  ? 3   GLN L HG3  1 
ATOM   3247 H HE21 . GLN B 2 3   ? -12.40896 -5.44243  27.60698  1.000 68.25330  ? 3   GLN L HE21 1 
ATOM   3248 H HE22 . GLN B 2 3   ? -11.95835 -5.26893  26.19785  1.000 68.25330  ? 3   GLN L HE22 1 
ATOM   3249 N N    . MET B 2 4   ? -9.14974  -1.37234  29.88161  1.000 24.37513  ? 4   MET L N    1 
ATOM   3250 C CA   . MET B 2 4   ? -8.33473  -0.25279  30.32626  1.000 24.29644  ? 4   MET L CA   1 
ATOM   3251 C C    . MET B 2 4   ? -8.17228  0.67566   29.13770  1.000 23.35366  ? 4   MET L C    1 
ATOM   3252 O O    . MET B 2 4   ? -7.72929  0.24493   28.06873  1.000 22.32375  ? 4   MET L O    1 
ATOM   3253 C CB   . MET B 2 4   ? -6.98541  -0.73358  30.84806  1.000 19.04064  ? 4   MET L CB   1 
ATOM   3254 C CG   . MET B 2 4   ? -7.12462  -1.66589  32.02686  1.000 20.80045  ? 4   MET L CG   1 
ATOM   3255 S SD   . MET B 2 4   ? -5.53494  -2.18091  32.66834  1.000 21.71036  ? 4   MET L SD   1 
ATOM   3256 C CE   . MET B 2 4   ? -4.95892  -0.68351  33.46183  1.000 22.15891  ? 4   MET L CE   1 
ATOM   3257 H H    . MET B 2 4   ? -8.82506  -1.77909  29.19697  1.000 29.25699  ? 4   MET L H    1 
ATOM   3258 H HA   . MET B 2 4   ? -8.76774  0.21992   31.05424  1.000 29.16257  ? 4   MET L HA   1 
ATOM   3259 H HB2  . MET B 2 4   ? -6.52261  -1.20866  30.14023  1.000 22.85560  ? 4   MET L HB2  1 
ATOM   3260 H HB3  . MET B 2 4   ? -6.46266  0.03344   31.12969  1.000 22.85560  ? 4   MET L HB3  1 
ATOM   3261 H HG2  . MET B 2 4   ? -7.60524  -1.21232  32.73691  1.000 24.96738  ? 4   MET L HG2  1 
ATOM   3262 H HG3  . MET B 2 4   ? -7.61097  -2.45842  31.75070  1.000 24.96738  ? 4   MET L HG3  1 
ATOM   3263 H HE1  . MET B 2 4   ? -4.12010  -0.86768  33.91278  1.000 26.59752  ? 4   MET L HE1  1 
ATOM   3264 H HE2  . MET B 2 4   ? -4.82846  0.00123   32.78729  1.000 26.59752  ? 4   MET L HE2  1 
ATOM   3265 H HE3  . MET B 2 4   ? -5.62332  -0.39151  34.10543  1.000 26.59752  ? 4   MET L HE3  1 
ATOM   3266 N N    . THR B 2 5   ? -8.56179  1.93106   29.31340  1.000 20.65987  ? 5   THR L N    1 
ATOM   3267 C CA   . THR B 2 5   ? -8.53654  2.91261   28.23883  1.000 19.97216  ? 5   THR L CA   1 
ATOM   3268 C C    . THR B 2 5   ? -7.62433  4.05983   28.63433  1.000 17.37146  ? 5   THR L C    1 
ATOM   3269 O O    . THR B 2 5   ? -7.81991  4.67643   29.68867  1.000 17.50615  ? 5   THR L O    1 
ATOM   3270 C CB   . THR B 2 5   ? -9.94175  3.44051   27.94148  1.000 26.29755  ? 5   THR L CB   1 
ATOM   3271 O OG1  . THR B 2 5   ? -10.84861 2.34278   27.78453  1.000 28.68027  ? 5   THR L OG1  1 
ATOM   3272 C CG2  . THR B 2 5   ? -9.93332  4.27755   26.67328  1.000 27.55660  ? 5   THR L CG2  1 
ATOM   3273 H H    . THR B 2 5   ? -8.85026  2.24358   30.06087  1.000 24.79868  ? 5   THR L H    1 
ATOM   3274 H HA   . THR B 2 5   ? -8.18129  2.49565   27.43830  1.000 23.97342  ? 5   THR L HA   1 
ATOM   3275 H HB   . THR B 2 5   ? -10.24149 3.99834   28.67624  1.000 31.56389  ? 5   THR L HB   1 
ATOM   3276 H HG1  . THR B 2 5   ? -10.90964 1.91527   28.50502  1.000 34.42315  ? 5   THR L HG1  1 
ATOM   3277 H HG21 . THR B 2 5   ? -10.83794 4.54291   26.44491  1.000 33.07476  ? 5   THR L HG21 1 
ATOM   3278 H HG22 . THR B 2 5   ? -9.39541  5.07392   26.80496  1.000 33.07476  ? 5   THR L HG22 1 
ATOM   3279 H HG23 . THR B 2 5   ? -9.56111  3.76406   25.93933  1.000 33.07476  ? 5   THR L HG23 1 
ATOM   3280 N N    . GLN B 2 6   ? -6.64386  4.34811   27.78881  1.000 16.59749  ? 6   GLN L N    1 
ATOM   3281 C CA   . GLN B 2 6   ? -5.72122  5.44929   28.00596  1.000 16.82296  ? 6   GLN L CA   1 
ATOM   3282 C C    . GLN B 2 6   ? -6.14494  6.67179   27.20125  1.000 19.12072  ? 6   GLN L C    1 
ATOM   3283 O O    . GLN B 2 6   ? -6.74488  6.55948   26.12903  1.000 18.06978  ? 6   GLN L O    1 
ATOM   3284 C CB   . GLN B 2 6   ? -4.29693  5.03822   27.62422  1.000 17.94954  ? 6   GLN L CB   1 
ATOM   3285 C CG   . GLN B 2 6   ? -3.84327  3.78564   28.35203  1.000 17.16880  ? 6   GLN L CG   1 
ATOM   3286 C CD   . GLN B 2 6   ? -2.43029  3.33886   28.01059  1.000 16.49550  ? 6   GLN L CD   1 
ATOM   3287 O OE1  . GLN B 2 6   ? -2.09935  2.16782   28.17435  1.000 15.17205  ? 6   GLN L OE1  1 
ATOM   3288 N NE2  . GLN B 2 6   ? -1.58638  4.26742   27.56029  1.000 16.38947  ? 6   GLN L NE2  1 
ATOM   3289 H H    . GLN B 2 6   ? -6.49051  3.90888   27.06551  1.000 19.92382  ? 6   GLN L H    1 
ATOM   3290 H HA   . GLN B 2 6   ? -5.72775  5.69584   28.94408  1.000 20.19438  ? 6   GLN L HA   1 
ATOM   3291 H HB2  . GLN B 2 6   ? -4.26202  4.86308   26.67080  1.000 21.54629  ? 6   GLN L HB2  1 
ATOM   3292 H HB3  . GLN B 2 6   ? -3.68730  5.75752   27.85194  1.000 21.54629  ? 6   GLN L HB3  1 
ATOM   3293 H HG2  . GLN B 2 6   ? -3.87496  3.95337   29.30689  1.000 20.60940  ? 6   GLN L HG2  1 
ATOM   3294 H HG3  . GLN B 2 6   ? -4.44384  3.05926   28.12268  1.000 20.60940  ? 6   GLN L HG3  1 
ATOM   3295 H HE21 . GLN B 2 6   ? -1.84941  5.08157   27.47319  1.000 19.67420  ? 6   GLN L HE21 1 
ATOM   3296 H HE22 . GLN B 2 6   ? -0.77894  4.05231   27.35689  1.000 19.67420  ? 6   GLN L HE22 1 
ATOM   3297 N N    . SER B 2 7   ? -5.82046  7.84510   27.73957  1.000 15.89019  ? 7   SER L N    1 
ATOM   3298 C CA   . SER B 2 7   ? -6.09132  9.12773   27.10007  1.000 16.99595  ? 7   SER L CA   1 
ATOM   3299 C C    . SER B 2 7   ? -4.83066  9.97216   27.22234  1.000 17.59362  ? 7   SER L C    1 
ATOM   3300 O O    . SER B 2 7   ? -4.32210  10.16653  28.34957  1.000 15.31904  ? 7   SER L O    1 
ATOM   3301 C CB   . SER B 2 7   ? -7.28335  9.84211   27.74646  1.000 19.84554  ? 7   SER L CB   1 
ATOM   3302 O OG   . SER B 2 7   ? -8.42330  9.00584   27.80532  1.000 20.70677  ? 7   SER L OG   1 
ATOM   3303 H H    . SER B 2 7   ? -5.42907  7.92574   28.50109  1.000 19.07506  ? 7   SER L H    1 
ATOM   3304 H HA   . SER B 2 7   ? -6.29969  8.98452   26.16360  1.000 20.40197  ? 7   SER L HA   1 
ATOM   3305 H HB2  . SER B 2 7   ? -7.03994  10.10274  28.64852  1.000 23.82149  ? 7   SER L HB2  1 
ATOM   3306 H HB3  . SER B 2 7   ? -7.49919  10.62825  27.22082  1.000 23.82149  ? 7   SER L HB3  1 
ATOM   3307 H HG   . SER B 2 7   ? -9.05835  9.41149   28.17648  1.000 24.85496  ? 7   SER L HG   1 
ATOM   3308 N N    . PRO B 2 8   ? -4.27480  10.48529  26.11733  1.000 16.25215  ? 8   PRO L N    1 
ATOM   3309 C CA   . PRO B 2 8   ? -4.70147  10.28298  24.73114  1.000 16.56451  ? 8   PRO L CA   1 
ATOM   3310 C C    . PRO B 2 8   ? -4.10891  8.98791   24.18997  1.000 20.28605  ? 8   PRO L C    1 
ATOM   3311 O O    . PRO B 2 8   ? -3.35533  8.33639   24.91500  1.000 17.43649  ? 8   PRO L O    1 
ATOM   3312 C CB   . PRO B 2 8   ? -4.12909  11.50486  24.02120  1.000 18.30125  ? 8   PRO L CB   1 
ATOM   3313 C CG   . PRO B 2 8   ? -2.83940  11.74842  24.72994  1.000 19.69394  ? 8   PRO L CG   1 
ATOM   3314 C CD   . PRO B 2 8   ? -3.05649  11.31623  26.18426  1.000 16.99989  ? 8   PRO L CD   1 
ATOM   3315 H HA   . PRO B 2 8   ? -5.66524  10.28666  24.62140  1.000 19.88424  ? 8   PRO L HA   1 
ATOM   3316 H HB2  . PRO B 2 8   ? -3.98386  11.31044  23.08204  1.000 21.96834  ? 8   PRO L HB2  1 
ATOM   3317 H HB3  . PRO B 2 8   ? -4.73058  12.26011  24.11448  1.000 21.96834  ? 8   PRO L HB3  1 
ATOM   3318 H HG2  . PRO B 2 8   ? -2.13753  11.22063  24.31796  1.000 23.63956  ? 8   PRO L HG2  1 
ATOM   3319 H HG3  . PRO B 2 8   ? -2.61616  12.69124  24.68354  1.000 23.63956  ? 8   PRO L HG3  1 
ATOM   3320 H HD2  . PRO B 2 8   ? -2.30265  10.79733  26.50578  1.000 20.40670  ? 8   PRO L HD2  1 
ATOM   3321 H HD3  . PRO B 2 8   ? -3.19628  12.08742  26.75577  1.000 20.40670  ? 8   PRO L HD3  1 
ATOM   3322 N N    . SER B 2 9   ? -4.42906  8.61645   22.95160  1.000 18.24283  ? 9   SER L N    1 
ATOM   3323 C CA   . SER B 2 9   ? -3.78765  7.45598   22.34104  1.000 19.25065  ? 9   SER L CA   1 
ATOM   3324 C C    . SER B 2 9   ? -2.45018  7.80190   21.70092  1.000 16.15203  ? 9   SER L C    1 
ATOM   3325 O O    . SER B 2 9   ? -1.64519  6.90202   21.44726  1.000 17.75627  ? 9   SER L O    1 
ATOM   3326 C CB   . SER B 2 9   ? -4.71677  6.83021   21.29932  1.000 22.22402  ? 9   SER L CB   1 
ATOM   3327 O OG   . SER B 2 9   ? -5.76022  6.11179   21.93841  1.000 22.92942  ? 9   SER L OG   1 
ATOM   3328 H H    . SER B 2 9   ? -5.00557  9.01376   22.45223  1.000 21.89823  ? 9   SER L H    1 
ATOM   3329 H HA   . SER B 2 9   ? -3.62432  6.78987   23.02698  1.000 23.10761  ? 9   SER L HA   1 
ATOM   3330 H HB2  . SER B 2 9   ? -5.10269  7.53361   20.75417  1.000 26.67566  ? 9   SER L HB2  1 
ATOM   3331 H HB3  . SER B 2 9   ? -4.20623  6.22149   20.74281  1.000 26.67566  ? 9   SER L HB3  1 
ATOM   3332 H HG   . SER B 2 9   ? -6.26062  5.75936   21.36309  1.000 27.52213  ? 9   SER L HG   1 
ATOM   3333 N N    . SER B 2 10  ? -2.19422  9.07823   21.43856  1.000 17.93716  ? 10  SER L N    1 
ATOM   3334 C CA   . SER B 2 10  ? -0.90311  9.49408   20.91407  1.000 16.45016  ? 10  SER L CA   1 
ATOM   3335 C C    . SER B 2 10  ? -0.74609  10.98191  21.16316  1.000 18.18662  ? 10  SER L C    1 
ATOM   3336 O O    . SER B 2 10  ? -1.73446  11.71926  21.26368  1.000 14.67506  ? 10  SER L O    1 
ATOM   3337 C CB   . SER B 2 10  ? -0.76826  9.19010   19.41821  1.000 24.31281  ? 10  SER L CB   1 
ATOM   3338 O OG   . SER B 2 10  ? -1.66163  9.99041   18.67332  1.000 29.83454  ? 10  SER L OG   1 
ATOM   3339 H H    . SER B 2 10  ? -2.75269  9.72155   21.55622  1.000 21.53143  ? 10  SER L H    1 
ATOM   3340 H HA   . SER B 2 10  ? -0.19681  9.01968   21.37987  1.000 19.74702  ? 10  SER L HA   1 
ATOM   3341 H HB2  . SER B 2 10  ? 0.14003   9.38019   19.13576  1.000 29.18221  ? 10  SER L HB2  1 
ATOM   3342 H HB3  . SER B 2 10  ? -0.97483  8.25499   19.26392  1.000 29.18221  ? 10  SER L HB3  1 
ATOM   3343 H HG   . SER B 2 10  ? -1.58466  9.82081   17.85422  1.000 35.80828  ? 10  SER L HG   1 
ATOM   3344 N N    . LEU B 2 11  ? 0.50650   11.41232  21.26060  1.000 15.09235  ? 11  LEU L N    1 
ATOM   3345 C CA   . LEU B 2 11  ? 0.78872   12.80528  21.56967  1.000 17.84348  ? 11  LEU L CA   1 
ATOM   3346 C C    . LEU B 2 11  ? 2.20002   13.14137  21.12009  1.000 15.98133  ? 11  LEU L C    1 
ATOM   3347 O O    . LEU B 2 11  ? 3.06557   12.26788  21.02166  1.000 14.52431  ? 11  LEU L O    1 
ATOM   3348 C CB   . LEU B 2 11  ? 0.61977   13.07781  23.06743  1.000 15.69231  ? 11  LEU L CB   1 
ATOM   3349 C CG   . LEU B 2 11  ? 1.62017   12.39004  23.99457  1.000 14.81908  ? 11  LEU L CG   1 
ATOM   3350 C CD1  . LEU B 2 11  ? 2.77551   13.32323  24.34619  1.000 19.63529  ? 11  LEU L CD1  1 
ATOM   3351 C CD2  . LEU B 2 11  ? 0.92156   11.90067  25.24427  1.000 21.38637  ? 11  LEU L CD2  1 
ATOM   3352 H H    . LEU B 2 11  ? 1.20361   10.92037  21.15279  1.000 18.11766  ? 11  LEU L H    1 
ATOM   3353 H HA   . LEU B 2 11  ? 0.17798   13.37499  21.07639  1.000 21.41901  ? 11  LEU L HA   1 
ATOM   3354 H HB2  . LEU B 2 11  ? 0.70543   14.03317  23.21179  1.000 18.83760  ? 11  LEU L HB2  1 
ATOM   3355 H HB3  . LEU B 2 11  ? -0.26541  12.78063  23.33019  1.000 18.83760  ? 11  LEU L HB3  1 
ATOM   3356 H HG   . LEU B 2 11  ? 1.99841   11.62298  23.53690  1.000 17.78974  ? 11  LEU L HG   1 
ATOM   3357 H HD11 . LEU B 2 11  ? 3.35940   12.87799  24.98001  1.000 23.56918  ? 11  LEU L HD11 1 
ATOM   3358 H HD12 . LEU B 2 11  ? 3.26662   13.53645  23.53733  1.000 23.56918  ? 11  LEU L HD12 1 
ATOM   3359 H HD13 . LEU B 2 11  ? 2.41770   14.13451  24.73948  1.000 23.56918  ? 11  LEU L HD13 1 
ATOM   3360 H HD21 . LEU B 2 11  ? 1.57605   11.49323  25.83295  1.000 25.67048  ? 11  LEU L HD21 1 
ATOM   3361 H HD22 . LEU B 2 11  ? 0.50215   12.65473  25.68744  1.000 25.67048  ? 11  LEU L HD22 1 
ATOM   3362 H HD23 . LEU B 2 11  ? 0.24904   11.24764  24.99495  1.000 25.67048  ? 11  LEU L HD23 1 
ATOM   3363 N N    . SER B 2 12  ? 2.42176   14.43209  20.86271  1.000 15.24788  ? 12  SER L N    1 
ATOM   3364 C CA   . SER B 2 12  ? 3.73393   14.96697  20.53138  1.000 18.42319  ? 12  SER L CA   1 
ATOM   3365 C C    . SER B 2 12  ? 4.07202   16.09213  21.49743  1.000 16.12519  ? 12  SER L C    1 
ATOM   3366 O O    . SER B 2 12  ? 3.22704   16.94002  21.79767  1.000 19.02111  ? 12  SER L O    1 
ATOM   3367 C CB   . SER B 2 12  ? 3.78281   15.50419  19.09448  1.000 21.45443  ? 12  SER L CB   1 
ATOM   3368 O OG   . SER B 2 12  ? 3.04501   14.68397  18.21274  1.000 36.65569  ? 12  SER L OG   1 
ATOM   3369 H H    . SER B 2 12  ? 1.80550   15.03180  20.87556  1.000 18.30429  ? 12  SER L H    1 
ATOM   3370 H HA   . SER B 2 12  ? 4.39597   14.26278  20.61329  1.000 22.11466  ? 12  SER L HA   1 
ATOM   3371 H HB2  . SER B 2 12  ? 3.40592   16.39788  19.08080  1.000 25.75215  ? 12  SER L HB2  1 
ATOM   3372 H HB3  . SER B 2 12  ? 4.70679   15.52927  18.80031  1.000 25.75215  ? 12  SER L HB3  1 
ATOM   3373 H HG   . SER B 2 12  ? 3.07472   14.99903  17.43463  1.000 43.99366  ? 12  SER L HG   1 
ATOM   3374 N N    . ALA B 2 13  ? 5.31212   16.10923  21.96598  1.000 18.22236  ? 13  ALA L N    1 
ATOM   3375 C CA   . ALA B 2 13  ? 5.75115   17.12942  22.90408  1.000 19.80782  ? 13  ALA L CA   1 
ATOM   3376 C C    . ALA B 2 13  ? 7.23595   17.37426  22.70421  1.000 20.34186  ? 13  ALA L C    1 
ATOM   3377 O O    . ALA B 2 13  ? 7.96118   16.52674  22.17909  1.000 18.06175  ? 13  ALA L O    1 
ATOM   3378 C CB   . ALA B 2 13  ? 5.46551   16.72138  24.35352  1.000 19.14400  ? 13  ALA L CB   1 
ATOM   3379 H H    . ALA B 2 13  ? 5.91992   15.53864  21.75476  1.000 21.87366  ? 13  ALA L H    1 
ATOM   3380 H HA   . ALA B 2 13  ? 5.27909   17.95734  22.72350  1.000 23.77622  ? 13  ALA L HA   1 
ATOM   3381 H HB1  . ALA B 2 13  ? 5.86734   17.37237  24.94989  1.000 22.97964  ? 13  ALA L HB1  1 
ATOM   3382 H HB2  . ALA B 2 13  ? 4.50565   16.69513  24.49090  1.000 22.97964  ? 13  ALA L HB2  1 
ATOM   3383 H HB3  . ALA B 2 13  ? 5.84699   15.84442  24.51574  1.000 22.97964  ? 13  ALA L HB3  1 
ATOM   3384 N N    . SER B 2 14  ? 7.67905   18.54753  23.13594  1.000 16.62067  ? 14  SER L N    1 
ATOM   3385 C CA   . SER B 2 14  ? 9.06963   18.94683  23.00182  1.000 22.94635  ? 14  SER L CA   1 
ATOM   3386 C C    . SER B 2 14  ? 9.85594   18.58790  24.25896  1.000 22.86363  ? 14  SER L C    1 
ATOM   3387 O O    . SER B 2 14  ? 9.29944   18.44514  25.35095  1.000 18.94276  ? 14  SER L O    1 
ATOM   3388 C CB   . SER B 2 14  ? 9.16737   20.45039  22.74145  1.000 27.90292  ? 14  SER L CB   1 
ATOM   3389 O OG   . SER B 2 14  ? 8.41435   20.81848  21.60188  1.000 28.44807  ? 14  SER L OG   1 
ATOM   3390 H H    . SER B 2 14  ? 7.18413   19.13904  23.51644  1.000 19.95164  ? 14  SER L H    1 
ATOM   3391 H HA   . SER B 2 14  ? 9.46695   18.47796  22.25135  1.000 27.54245  ? 14  SER L HA   1 
ATOM   3392 H HB2  . SER B 2 14  ? 8.82369   20.92672  23.51340  1.000 33.49034  ? 14  SER L HB2  1 
ATOM   3393 H HB3  . SER B 2 14  ? 10.09699  20.68472  22.59385  1.000 33.49034  ? 14  SER L HB3  1 
ATOM   3394 H HG   . SER B 2 14  ? 8.70240   20.41412  20.92429  1.000 34.14452  ? 14  SER L HG   1 
ATOM   3395 N N    . VAL B 2 15  ? 11.17527  18.45152  24.09123  1.000 23.55636  ? 15  VAL L N    1 
ATOM   3396 C CA   . VAL B 2 15  ? 12.04818  18.22161  25.23715  1.000 19.54530  ? 15  VAL L CA   1 
ATOM   3397 C C    . VAL B 2 15  ? 11.78312  19.29555  26.27775  1.000 23.01016  ? 15  VAL L C    1 
ATOM   3398 O O    . VAL B 2 15  ? 11.67571  20.48135  25.94912  1.000 22.57553  ? 15  VAL L O    1 
ATOM   3399 C CB   . VAL B 2 15  ? 13.52212  18.20320  24.79046  1.000 20.74224  ? 15  VAL L CB   1 
ATOM   3400 C CG1  . VAL B 2 15  ? 14.45342  18.24086  25.99543  1.000 27.11159  ? 15  VAL L CG1  1 
ATOM   3401 C CG2  . VAL B 2 15  ? 13.80094  16.96987  23.94962  1.000 23.01758  ? 15  VAL L CG2  1 
ATOM   3402 H H    . VAL B 2 15  ? 11.58095  18.48803  23.33381  1.000 28.27446  ? 15  VAL L H    1 
ATOM   3403 H HA   . VAL B 2 15  ? 11.84710  17.35729  25.62884  1.000 23.46120  ? 15  VAL L HA   1 
ATOM   3404 H HB   . VAL B 2 15  ? 13.69350  18.99177  24.25224  1.000 24.89752  ? 15  VAL L HB   1 
ATOM   3405 H HG11 . VAL B 2 15  ? 15.34621  17.98824  25.71256  1.000 32.54074  ? 15  VAL L HG11 1 
ATOM   3406 H HG12 . VAL B 2 15  ? 14.46361  19.14020  26.35870  1.000 32.54074  ? 15  VAL L HG12 1 
ATOM   3407 H HG13 . VAL B 2 15  ? 14.12964  17.61754  26.66441  1.000 32.54074  ? 15  VAL L HG13 1 
ATOM   3408 H HG21 . VAL B 2 15  ? 14.67527  17.05862  23.53905  1.000 27.62794  ? 15  VAL L HG21 1 
ATOM   3409 H HG22 . VAL B 2 15  ? 13.78211  16.18676  24.52171  1.000 27.62794  ? 15  VAL L HG22 1 
ATOM   3410 H HG23 . VAL B 2 15  ? 13.11940  16.89474  23.26350  1.000 27.62794  ? 15  VAL L HG23 1 
ATOM   3411 N N    . GLY B 2 16  ? 11.64272  18.88049  27.53798  1.000 20.29435  ? 16  GLY L N    1 
ATOM   3412 C CA   . GLY B 2 16  ? 11.33448  19.78664  28.62193  1.000 22.24668  ? 16  GLY L CA   1 
ATOM   3413 C C    . GLY B 2 16  ? 9.85954   19.93936  28.93700  1.000 26.93961  ? 16  GLY L C    1 
ATOM   3414 O O    . GLY B 2 16  ? 9.52120   20.46248  30.00427  1.000 25.83907  ? 16  GLY L O    1 
ATOM   3415 H H    . GLY B 2 16  ? 11.72464  18.06104  27.78572  1.000 24.36005  ? 16  GLY L H    1 
ATOM   3416 H HA2  . GLY B 2 16  ? 11.77554  19.46894  29.42532  1.000 26.70285  ? 16  GLY L HA2  1 
ATOM   3417 H HA3  . GLY B 2 16  ? 11.67999  20.66499  28.39829  1.000 26.70285  ? 16  GLY L HA3  1 
ATOM   3418 N N    . ASP B 2 17  ? 8.97153   19.50660  28.04425  1.000 21.13236  ? 17  ASP L N    1 
ATOM   3419 C CA   . ASP B 2 17  ? 7.54205   19.62076  28.29474  1.000 18.89068  ? 17  ASP L CA   1 
ATOM   3420 C C    . ASP B 2 17  ? 7.10340   18.66513  29.39786  1.000 19.43014  ? 17  ASP L C    1 
ATOM   3421 O O    . ASP B 2 17  ? 7.61412   17.54870  29.52911  1.000 17.22668  ? 17  ASP L O    1 
ATOM   3422 C CB   . ASP B 2 17  ? 6.73236   19.31056  27.03024  1.000 22.55038  ? 17  ASP L CB   1 
ATOM   3423 C CG   . ASP B 2 17  ? 6.71909   20.45778  26.02319  1.000 32.28994  ? 17  ASP L CG   1 
ATOM   3424 O OD1  . ASP B 2 17  ? 7.28056   21.53711  26.31203  1.000 30.67440  ? 17  ASP L OD1  1 
ATOM   3425 O OD2  . ASP B 2 17  ? 6.13445   20.26686  24.92930  1.000 32.95561  ? 17  ASP L OD2  1 
ATOM   3426 H H    . ASP B 2 17  ? 9.17209   19.14514  27.29012  1.000 25.36567  ? 17  ASP L H    1 
ATOM   3427 H HA   . ASP B 2 17  ? 7.35436   20.53220  28.56849  1.000 22.67564  ? 17  ASP L HA   1 
ATOM   3428 H HB2  . ASP B 2 17  ? 7.11817   18.53546  26.59290  1.000 27.06730  ? 17  ASP L HB2  1 
ATOM   3429 H HB3  . ASP B 2 17  ? 5.81420   19.12613  27.28297  1.000 27.06730  ? 17  ASP L HB3  1 
ATOM   3430 N N    . ARG B 2 18  ? 6.13464   19.11361  30.18636  1.000 18.78651  ? 18  ARG L N    1 
ATOM   3431 C CA   . ARG B 2 18  ? 5.44506   18.24072  31.12801  1.000 18.28279  ? 18  ARG L CA   1 
ATOM   3432 C C    . ARG B 2 18  ? 4.34386   17.49274  30.38485  1.000 20.27709  ? 18  ARG L C    1 
ATOM   3433 O O    . ARG B 2 18  ? 3.56162   18.10249  29.64834  1.000 18.30725  ? 18  ARG L O    1 
ATOM   3434 C CB   . ARG B 2 18  ? 4.87010   19.06596  32.27533  1.000 24.56151  ? 18  ARG L CB   1 
ATOM   3435 C CG   . ARG B 2 18  ? 4.22427   18.27047  33.40268  1.000 25.24884  ? 18  ARG L CG   1 
ATOM   3436 C CD   . ARG B 2 18  ? 4.08359   19.15659  34.64272  1.000 25.50832  ? 18  ARG L CD   1 
ATOM   3437 N NE   . ARG B 2 18  ? 3.15916   18.62191  35.63370  1.000 36.23601  ? 18  ARG L NE   1 
ATOM   3438 C CZ   . ARG B 2 18  ? 3.51546   17.94249  36.71711  1.000 48.54876  ? 18  ARG L CZ   1 
ATOM   3439 N NH1  . ARG B 2 18  ? 4.78279   17.64711  36.96757  1.000 45.08362  ? 18  ARG L NH1  1 
ATOM   3440 N NH2  . ARG B 2 18  ? 2.57524   17.55391  37.57456  1.000 35.74473  ? 18  ARG L NH2  1 
ATOM   3441 H H    . ARG B 2 18  ? 5.85508   19.92685  30.19573  1.000 22.55065  ? 18  ARG L H    1 
ATOM   3442 H HA   . ARG B 2 18  ? 6.05639   17.59206  31.51065  1.000 21.94618  ? 18  ARG L HA   1 
ATOM   3443 H HB2  . ARG B 2 18  ? 5.58938   19.58656  32.66587  1.000 29.48065  ? 18  ARG L HB2  1 
ATOM   3444 H HB3  . ARG B 2 18  ? 4.19090   19.65699  31.91439  1.000 29.48065  ? 18  ARG L HB3  1 
ATOM   3445 H HG2  . ARG B 2 18  ? 3.34256   17.97159  33.13036  1.000 30.30544  ? 18  ARG L HG2  1 
ATOM   3446 H HG3  . ARG B 2 18  ? 4.77930   17.50680  33.62548  1.000 30.30544  ? 18  ARG L HG3  1 
ATOM   3447 H HD2  . ARG B 2 18  ? 4.95238   19.24609  35.06473  1.000 30.61681  ? 18  ARG L HD2  1 
ATOM   3448 H HD3  . ARG B 2 18  ? 3.75575   20.02791  34.37029  1.000 30.61681  ? 18  ARG L HD3  1 
ATOM   3449 H HE   . ARG B 2 18  ? 2.31923   18.75659  35.50728  1.000 43.49005  ? 18  ARG L HE   1 
ATOM   3450 H HH11 . ARG B 2 18  ? 5.39851   17.89672  36.42150  1.000 54.10718  ? 18  ARG L HH11 1 
ATOM   3451 H HH12 . ARG B 2 18  ? 4.98953   17.20581  37.67616  1.000 54.10718  ? 18  ARG L HH12 1 
ATOM   3452 H HH21 . ARG B 2 18  ? 1.75020   17.74353  37.42303  1.000 42.90051  ? 18  ARG L HH21 1 
ATOM   3453 H HH22 . ARG B 2 18  ? 2.79254   17.11313  38.28031  1.000 42.90051  ? 18  ARG L HH22 1 
ATOM   3454 N N    . VAL B 2 19  ? 4.29381   16.17185  30.55910  1.000 15.60795  ? 19  VAL L N    1 
ATOM   3455 C CA   . VAL B 2 19  ? 3.36267   15.31912  29.82541  1.000 16.51816  ? 19  VAL L CA   1 
ATOM   3456 C C    . VAL B 2 19  ? 2.57404   14.45489  30.80371  1.000 15.19777  ? 19  VAL L C    1 
ATOM   3457 O O    . VAL B 2 19  ? 3.13919   13.90633  31.75134  1.000 14.29144  ? 19  VAL L O    1 
ATOM   3458 C CB   . VAL B 2 19  ? 4.10623   14.43005  28.80772  1.000 20.24027  ? 19  VAL L CB   1 
ATOM   3459 C CG1  . VAL B 2 19  ? 3.15555   13.38918  28.23216  1.000 22.29096  ? 19  VAL L CG1  1 
ATOM   3460 C CG2  . VAL B 2 19  ? 4.70517   15.28062  27.70061  1.000 22.01295  ? 19  VAL L CG2  1 
ATOM   3461 H H    . VAL B 2 19  ? 4.79842   15.74118  31.10635  1.000 18.73638  ? 19  VAL L H    1 
ATOM   3462 H HA   . VAL B 2 19  ? 2.72912   15.88356  29.35538  1.000 19.82863  ? 19  VAL L HA   1 
ATOM   3463 H HB   . VAL B 2 19  ? 4.83129   13.96728  29.25609  1.000 24.29515  ? 19  VAL L HB   1 
ATOM   3464 H HG11 . VAL B 2 19  ? 3.52180   13.05333  27.39912  1.000 26.75599  ? 19  VAL L HG11 1 
ATOM   3465 H HG12 . VAL B 2 19  ? 3.05989   12.66296  28.86805  1.000 26.75599  ? 19  VAL L HG12 1 
ATOM   3466 H HG13 . VAL B 2 19  ? 2.29344   13.80362  28.07120  1.000 26.75599  ? 19  VAL L HG13 1 
ATOM   3467 H HG21 . VAL B 2 19  ? 5.16202   14.70221  27.07004  1.000 26.42237  ? 19  VAL L HG21 1 
ATOM   3468 H HG22 . VAL B 2 19  ? 3.99270   15.76203  27.25168  1.000 26.42237  ? 19  VAL L HG22 1 
ATOM   3469 H HG23 . VAL B 2 19  ? 5.33431   15.90808  28.08970  1.000 26.42237  ? 19  VAL L HG23 1 
ATOM   3470 N N    . THR B 2 20  ? 1.27160   14.30961  30.55609  1.000 15.41897  ? 20  THR L N    1 
ATOM   3471 C CA   . THR B 2 20  ? 0.38910   13.51462  31.40539  1.000 12.93376  ? 20  THR L CA   1 
ATOM   3472 C C    . THR B 2 20  ? -0.37223  12.50939  30.55048  1.000 15.54034  ? 20  THR L C    1 
ATOM   3473 O O    . THR B 2 20  ? -0.84863  12.84008  29.46182  1.000 16.74447  ? 20  THR L O    1 
ATOM   3474 C CB   . THR B 2 20  ? -0.61284  14.40449  32.17255  1.000 20.58558  ? 20  THR L CB   1 
ATOM   3475 O OG1  . THR B 2 20  ? 0.08842   15.25259  33.09553  1.000 19.29223  ? 20  THR L OG1  1 
ATOM   3476 C CG2  . THR B 2 20  ? -1.61712  13.55534  32.93820  1.000 24.03680  ? 20  THR L CG2  1 
ATOM   3477 H H    . THR B 2 20  ? 0.86912   14.67041  29.88719  1.000 18.50960  ? 20  THR L H    1 
ATOM   3478 H HA   . THR B 2 20  ? 0.92255   13.02774  32.05291  1.000 15.52734  ? 20  THR L HA   1 
ATOM   3479 H HB   . THR B 2 20  ? -1.09742  14.95260  31.53564  1.000 24.70953  ? 20  THR L HB   1 
ATOM   3480 H HG1  . THR B 2 20  ? 0.59556   15.77530  32.67699  1.000 23.15752  ? 20  THR L HG1  1 
ATOM   3481 H HG21 . THR B 2 20  ? -2.06876  14.09608  33.60492  1.000 28.85099  ? 20  THR L HG21 1 
ATOM   3482 H HG22 . THR B 2 20  ? -2.27750  13.19154  32.32791  1.000 28.85099  ? 20  THR L HG22 1 
ATOM   3483 H HG23 . THR B 2 20  ? -1.16191  12.82303  33.38251  1.000 28.85099  ? 20  THR L HG23 1 
ATOM   3484 N N    . ILE B 2 21  ? -0.47504  11.28071  31.04843  1.000 11.70578  ? 21  ILE L N    1 
ATOM   3485 C CA   . ILE B 2 21  ? -1.23121  10.21268  30.41127  1.000 11.53006  ? 21  ILE L CA   1 
ATOM   3486 C C    . ILE B 2 21  ? -2.18192  9.64718   31.45530  1.000 16.33693  ? 21  ILE L C    1 
ATOM   3487 O O    . ILE B 2 21  ? -1.76068  9.33915   32.57609  1.000 13.94286  ? 21  ILE L O    1 
ATOM   3488 C CB   . ILE B 2 21  ? -0.31510  9.10344   29.85928  1.000 12.89530  ? 21  ILE L CB   1 
ATOM   3489 C CG1  . ILE B 2 21  ? 0.66809   9.67288   28.83643  1.000 15.43531  ? 21  ILE L CG1  1 
ATOM   3490 C CG2  . ILE B 2 21  ? -1.15374  7.99246   29.22479  1.000 15.89409  ? 21  ILE L CG2  1 
ATOM   3491 C CD1  . ILE B 2 21  ? 1.76703   8.69579   28.44587  1.000 21.09481  ? 21  ILE L CD1  1 
ATOM   3492 H H    . ILE B 2 21  ? -0.10041  11.03457  31.78237  1.000 14.05377  ? 21  ILE L H    1 
ATOM   3493 H HA   . ILE B 2 21  ? -1.74487  10.57035  29.67024  1.000 13.84291  ? 21  ILE L HA   1 
ATOM   3494 H HB   . ILE B 2 21  ? 0.19230   8.73374   30.59872  1.000 15.48120  ? 21  ILE L HB   1 
ATOM   3495 H HG12 . ILE B 2 21  ? 0.18089   9.90992   28.03185  1.000 18.52920  ? 21  ILE L HG12 1 
ATOM   3496 H HG13 . ILE B 2 21  ? 1.09043   10.46083  29.21281  1.000 18.52920  ? 21  ILE L HG13 1 
ATOM   3497 H HG21 . ILE B 2 21  ? -0.56109  7.35337   28.79908  1.000 19.07974  ? 21  ILE L HG21 1 
ATOM   3498 H HG22 . ILE B 2 21  ? -1.67157  7.55300   29.91733  1.000 19.07974  ? 21  ILE L HG22 1 
ATOM   3499 H HG23 . ILE B 2 21  ? -1.74794  8.38298   28.56500  1.000 19.07974  ? 21  ILE L HG23 1 
ATOM   3500 H HD11 . ILE B 2 21  ? 2.45262   9.17244   27.95224  1.000 25.32060  ? 21  ILE L HD11 1 
ATOM   3501 H HD12 . ILE B 2 21  ? 2.14688   8.30962   29.25053  1.000 25.32060  ? 21  ILE L HD12 1 
ATOM   3502 H HD13 . ILE B 2 21  ? 1.38589   7.99689   27.89164  1.000 25.32060  ? 21  ILE L HD13 1 
ATOM   3503 N N    . THR B 2 22  ? -3.45662  9.52065   31.10066  1.000 14.35631  ? 22  THR L N    1 
ATOM   3504 C CA   . THR B 2 22  ? -4.46621  9.00246   32.01252  1.000 13.70395  ? 22  THR L CA   1 
ATOM   3505 C C    . THR B 2 22  ? -4.88528  7.61467   31.55602  1.000 15.47753  ? 22  THR L C    1 
ATOM   3506 O O    . THR B 2 22  ? -4.93167  7.34066   30.36061  1.000 18.61062  ? 22  THR L O    1 
ATOM   3507 C CB   . THR B 2 22  ? -5.67955  9.93880   32.05539  1.000 21.44674  ? 22  THR L CB   1 
ATOM   3508 O OG1  . THR B 2 22  ? -5.25221  11.24466  32.46895  1.000 22.40061  ? 22  THR L OG1  1 
ATOM   3509 C CG2  . THR B 2 22  ? -6.73785  9.42634   33.02485  1.000 24.46773  ? 22  THR L CG2  1 
ATOM   3510 H H    . THR B 2 22  ? -3.76339  9.73193   30.32551  1.000 17.23441  ? 22  THR L H    1 
ATOM   3511 H HA   . THR B 2 22  ? -4.10822  8.93167   32.91126  1.000 16.45158  ? 22  THR L HA   1 
ATOM   3512 H HB   . THR B 2 22  ? -6.08087  9.98356   31.17344  1.000 25.74292  ? 22  THR L HB   1 
ATOM   3513 H HG1  . THR B 2 22  ? -5.88801  11.78955  32.40219  1.000 26.88757  ? 22  THR L HG1  1 
ATOM   3514 H HG21 . THR B 2 22  ? -7.42767  10.09710  33.14790  1.000 29.36812  ? 22  THR L HG21 1 
ATOM   3515 H HG22 . THR B 2 22  ? -7.14389  8.61759   32.67563  1.000 29.36812  ? 22  THR L HG22 1 
ATOM   3516 H HG23 . THR B 2 22  ? -6.33316  9.22966   33.88418  1.000 29.36812  ? 22  THR L HG23 1 
ATOM   3517 N N    . CYS B 2 23  ? -5.17921  6.73679   32.50189  1.000 15.71110  ? 23  CYS L N    1 
ATOM   3518 C CA   . CYS B 2 23  ? -5.71440  5.41788   32.19665  1.000 14.80209  ? 23  CYS L CA   1 
ATOM   3519 C C    . CYS B 2 23  ? -6.88250  5.15598   33.13270  1.000 19.42942  ? 23  CYS L C    1 
ATOM   3520 O O    . CYS B 2 23  ? -6.80495  5.45321   34.32507  1.000 17.31660  ? 23  CYS L O    1 
ATOM   3521 C CB   . CYS B 2 23  ? -4.63759  4.34347   32.34454  1.000 19.16416  ? 23  CYS L CB   1 
ATOM   3522 S SG   . CYS B 2 23  ? -5.18860  2.65518   31.97538  1.000 27.74972  ? 23  CYS L SG   1 
ATOM   3523 H H    . CYS B 2 23  ? -5.07593  6.88344   33.34298  1.000 18.86016  ? 23  CYS L H    1 
ATOM   3524 H HA   . CYS B 2 23  ? -6.03923  5.37395   31.28371  1.000 17.76934  ? 23  CYS L HA   1 
ATOM   3525 H HB2  . CYS B 2 23  ? -3.91008  4.55186   31.73774  1.000 23.00383  ? 23  CYS L HB2  1 
ATOM   3526 H HB3  . CYS B 2 23  ? -4.31845  4.35218   33.26049  1.000 23.00383  ? 23  CYS L HB3  1 
ATOM   3527 H HG   . CYS B 2 23  ? -5.60430  2.61711   30.85033  1.000 33.30650  ? 23  CYS L HG   1 
ATOM   3528 N N    . ARG B 2 24  ? -7.98261  4.64281   32.59147  1.000 20.10158  ? 24  ARG L N    1 
ATOM   3529 C CA   . ARG B 2 24  ? -9.14223  4.29830   33.40439  1.000 23.58350  ? 24  ARG L CA   1 
ATOM   3530 C C    . ARG B 2 24  ? -9.49804  2.83795   33.17804  1.000 20.00151  ? 24  ARG L C    1 
ATOM   3531 O O    . ARG B 2 24  ? -9.53697  2.36986   32.03618  1.000 20.98389  ? 24  ARG L O    1 
ATOM   3532 C CB   . ARG B 2 24  ? -10.34033 5.19820   33.10282  1.000 28.72615  ? 24  ARG L CB   1 
ATOM   3533 C CG   . ARG B 2 24  ? -10.67059 5.38535   31.63805  1.000 39.37936  ? 24  ARG L CG   1 
ATOM   3534 C CD   . ARG B 2 24  ? -12.04405 6.05446   31.48193  1.000 51.49142  ? 24  ARG L CD   1 
ATOM   3535 N NE   . ARG B 2 24  ? -12.38784 6.32016   30.08777  1.000 55.02263  ? 24  ARG L NE   1 
ATOM   3536 C CZ   . ARG B 2 24  ? -12.36740 7.51729   29.51013  1.000 62.59180  ? 24  ARG L CZ   1 
ATOM   3537 N NH1  . ARG B 2 24  ? -12.04213 8.61078   30.18259  1.000 54.10345  ? 24  ARG L NH1  1 
ATOM   3538 N NH2  . ARG B 2 24  ? -12.68837 7.62060   28.22369  1.000 59.07227  ? 24  ARG L NH2  1 
ATOM   3539 H H    . ARG B 2 24  ? -8.08040  4.48480   31.75178  1.000 24.12873  ? 24  ARG L H    1 
ATOM   3540 H HA   . ARG B 2 24  ? -8.91854  4.41671   34.34079  1.000 28.30704  ? 24  ARG L HA   1 
ATOM   3541 H HB2  . ARG B 2 24  ? -11.12340 4.81410   33.52727  1.000 34.47821  ? 24  ARG L HB2  1 
ATOM   3542 H HB3  . ARG B 2 24  ? -10.16065 6.07720   33.47157  1.000 34.47821  ? 24  ARG L HB3  1 
ATOM   3543 H HG2  . ARG B 2 24  ? -10.00124 5.95154   31.22297  1.000 47.26207  ? 24  ARG L HG2  1 
ATOM   3544 H HG3  . ARG B 2 24  ? -10.69471 4.52192   31.19667  1.000 47.26207  ? 24  ARG L HG3  1 
ATOM   3545 H HD2  . ARG B 2 24  ? -12.72427 5.47050   31.85232  1.000 61.79654  ? 24  ARG L HD2  1 
ATOM   3546 H HD3  . ARG B 2 24  ? -12.03931 6.90071   31.95599  1.000 61.79654  ? 24  ARG L HD3  1 
ATOM   3547 H HE   . ARG B 2 24  ? -12.62181 5.64981   29.60250  1.000 66.03399  ? 24  ARG L HE   1 
ATOM   3548 H HH11 . ARG B 2 24  ? -11.83663 8.55789   31.01600  1.000 64.93097  ? 24  ARG L HH11 1 
ATOM   3549 H HH12 . ARG B 2 24  ? -12.03639 9.37379   29.78588  1.000 64.93097  ? 24  ARG L HH12 1 
ATOM   3550 H HH21 . ARG B 2 24  ? -12.90537 6.91853   27.77692  1.000 70.89356  ? 24  ARG L HH21 1 
ATOM   3551 H HH22 . ARG B 2 24  ? -12.67893 8.38949   27.83855  1.000 70.89356  ? 24  ARG L HH22 1 
ATOM   3552 N N    . ALA B 2 25  ? -9.72433  2.12273   34.27059  1.000 18.08284  ? 25  ALA L N    1 
ATOM   3553 C CA   . ALA B 2 25  ? -10.08929 0.71719   34.23266  1.000 25.06551  ? 25  ALA L CA   1 
ATOM   3554 C C    . ALA B 2 25  ? -11.57502 0.57971   34.52272  1.000 22.63277  ? 25  ALA L C    1 
ATOM   3555 O O    . ALA B 2 25  ? -12.14107 1.34258   35.30668  1.000 19.42097  ? 25  ALA L O    1 
ATOM   3556 C CB   . ALA B 2 25  ? -9.28123  -0.08222  35.24999  1.000 19.73507  ? 25  ALA L CB   1 
ATOM   3557 H H    . ALA B 2 25  ? -9.67083  2.43969   35.06825  1.000 21.70624  ? 25  ALA L H    1 
ATOM   3558 H HA   . ALA B 2 25  ? -9.90459  0.34707   33.35528  1.000 30.08545  ? 25  ALA L HA   1 
ATOM   3559 H HB1  . ALA B 2 25  ? -9.54230  -1.01497  35.19795  1.000 23.68892  ? 25  ALA L HB1  1 
ATOM   3560 H HB2  . ALA B 2 25  ? -8.33742  0.00901   35.04554  1.000 23.68892  ? 25  ALA L HB2  1 
ATOM   3561 H HB3  . ALA B 2 25  ? -9.46210  0.26283   36.13832  1.000 23.68892  ? 25  ALA L HB3  1 
ATOM   3562 N N    . SER B 2 26  ? -12.20367 -0.40041  33.87231  1.000 22.95753  ? 26  SER L N    1 
ATOM   3563 C CA   . SER B 2 26  ? -13.62946 -0.63149  34.06273  1.000 28.32329  ? 26  SER L CA   1 
ATOM   3564 C C    . SER B 2 26  ? -13.95303 -1.22951  35.42784  1.000 28.79565  ? 26  SER L C    1 
ATOM   3565 O O    . SER B 2 26  ? -15.12350 -1.22774  35.81748  1.000 23.65876  ? 26  SER L O    1 
ATOM   3566 C CB   . SER B 2 26  ? -14.15671 -1.53358  32.94471  1.000 27.63124  ? 26  SER L CB   1 
ATOM   3567 O OG   . SER B 2 26  ? -13.38721 -2.71390  32.82470  1.000 26.13880  ? 26  SER L OG   1 
ATOM   3568 H H    . SER B 2 26  ? -11.82687 -0.94056  33.31925  1.000 27.55586  ? 26  SER L H    1 
ATOM   3569 H HA   . SER B 2 26  ? -14.09916 0.21518   34.00410  1.000 33.99478  ? 26  SER L HA   1 
ATOM   3570 H HB2  . SER B 2 26  ? -15.07407 -1.77688  33.14508  1.000 33.16432  ? 26  SER L HB2  1 
ATOM   3571 H HB3  . SER B 2 26  ? -14.11792 -1.04788  32.10596  1.000 33.16432  ? 26  SER L HB3  1 
ATOM   3572 H HG   . SER B 2 26  ? -13.72146 -3.21662  32.24062  1.000 31.37339  ? 26  SER L HG   1 
ATOM   3573 N N    . GLN B 2 27  ? -12.95654 -1.72289  36.16176  1.000 24.54456  ? 27  GLN L N    1 
ATOM   3574 C CA   . GLN B 2 27  ? -13.15468 -2.17057  37.53434  1.000 26.84593  ? 27  GLN L CA   1 
ATOM   3575 C C    . GLN B 2 27  ? -11.83904 -2.03036  38.28705  1.000 23.78041  ? 27  GLN L C    1 
ATOM   3576 O O    . GLN B 2 27  ? -10.76891 -1.91312  37.68561  1.000 23.05065  ? 27  GLN L O    1 
ATOM   3577 C CB   . GLN B 2 27  ? -13.66548 -3.61627  37.59027  1.000 31.29613  ? 27  GLN L CB   1 
ATOM   3578 C CG   . GLN B 2 27  ? -12.65891 -4.65408  37.12893  1.000 31.73934  ? 27  GLN L CG   1 
ATOM   3579 C CD   . GLN B 2 27  ? -13.27500 -6.03166  36.96454  1.000 40.53176  ? 27  GLN L CD   1 
ATOM   3580 O OE1  . GLN B 2 27  ? -13.90940 -6.32041  35.94854  1.000 36.45040  ? 27  GLN L OE1  1 
ATOM   3581 N NE2  . GLN B 2 27  ? -13.09115 -6.88989  37.96465  1.000 36.84505  ? 27  GLN L NE2  1 
ATOM   3582 H H    . GLN B 2 27  ? -12.14776 -1.80878  35.88229  1.000 29.46031  ? 27  GLN L H    1 
ATOM   3583 H HA   . GLN B 2 27  ? -13.81367 -1.60661  37.96862  1.000 32.22195  ? 27  GLN L HA   1 
ATOM   3584 H HB2  . GLN B 2 27  ? -13.90327 -3.82520  38.50717  1.000 37.56219  ? 27  GLN L HB2  1 
ATOM   3585 H HB3  . GLN B 2 27  ? -14.44643 -3.69083  37.01978  1.000 37.56219  ? 27  GLN L HB3  1 
ATOM   3586 H HG2  . GLN B 2 27  ? -12.29516 -4.38321  36.27148  1.000 38.09404  ? 27  GLN L HG2  1 
ATOM   3587 H HG3  . GLN B 2 27  ? -11.94775 -4.71922  37.78536  1.000 38.09404  ? 27  GLN L HG3  1 
ATOM   3588 H HE21 . GLN B 2 27  ? -12.64213 -6.65190  38.65844  1.000 44.22090  ? 27  GLN L HE21 1 
ATOM   3589 H HE22 . GLN B 2 27  ? -13.42135 -7.68255  37.91725  1.000 44.22090  ? 27  GLN L HE22 1 
ATOM   3590 N N    . SER B 2 28  A -11.93097 -2.03139  39.61470  1.000 20.67214  ? 27  SER L N    1 
ATOM   3591 C CA   . SER B 2 28  A -10.75952 -1.79076  40.44310  1.000 23.20582  ? 27  SER L CA   1 
ATOM   3592 C C    . SER B 2 28  A -9.76580  -2.93916  40.32060  1.000 21.91255  ? 27  SER L C    1 
ATOM   3593 O O    . SER B 2 28  A -10.13628 -4.10280  40.13853  1.000 20.82425  ? 27  SER L O    1 
ATOM   3594 C CB   . SER B 2 28  A -11.16467 -1.60415  41.90487  1.000 27.77828  ? 27  SER L CB   1 
ATOM   3595 O OG   . SER B 2 28  A -11.99346 -2.66586  42.33774  1.000 35.80092  ? 27  SER L OG   1 
ATOM   3596 H H    . SER B 2 28  A -12.65665 -2.16823  40.05544  1.000 24.81340  ? 27  SER L H    1 
ATOM   3597 H HA   . SER B 2 28  A -10.32055 -0.97803  40.14700  1.000 27.85382  ? 27  SER L HA   1 
ATOM   3598 H HB2  . SER B 2 28  A -10.36523 -1.58380  42.45385  1.000 33.34077  ? 27  SER L HB2  1 
ATOM   3599 H HB3  . SER B 2 28  A -11.64957 -0.76878  41.99383  1.000 33.34077  ? 27  SER L HB3  1 
ATOM   3600 H HG   . SER B 2 28  A -12.22864 -2.54033  43.13431  1.000 42.96793  ? 27  SER L HG   1 
ATOM   3601 N N    . VAL B 2 29  B -8.48670  -2.59532  40.43185  1.000 20.56074  ? 27  VAL L N    1 
ATOM   3602 C CA   . VAL B 2 29  B -7.40883  -3.56990  40.32571  1.000 20.15343  ? 27  VAL L CA   1 
ATOM   3603 C C    . VAL B 2 29  B -7.24736  -4.29029  41.65506  1.000 18.26720  ? 27  VAL L C    1 
ATOM   3604 O O    . VAL B 2 29  B -7.81869  -3.88213  42.67645  1.000 19.65674  ? 27  VAL L O    1 
ATOM   3605 C CB   . VAL B 2 29  B -6.08609  -2.90331  39.90255  1.000 18.41287  ? 27  VAL L CB   1 
ATOM   3606 C CG1  . VAL B 2 29  B -6.21936  -2.28435  38.51922  1.000 19.17909  ? 27  VAL L CG1  1 
ATOM   3607 C CG2  . VAL B 2 29  B -5.65987  -1.86334  40.92390  1.000 20.12613  ? 27  VAL L CG2  1 
ATOM   3608 H H    . VAL B 2 29  B -8.21413  -1.79162  40.57102  1.000 24.67972  ? 27  VAL L H    1 
ATOM   3609 H HA   . VAL B 2 29  B -7.64902  -4.22314  39.65008  1.000 24.19095  ? 27  VAL L HA   1 
ATOM   3610 H HB   . VAL B 2 29  B -5.39285  -3.58053  39.86144  1.000 22.10227  ? 27  VAL L HB   1 
ATOM   3611 H HG11 . VAL B 2 29  B -5.45132  -1.71590  38.35227  1.000 23.02174  ? 27  VAL L HG11 1 
ATOM   3612 H HG12 . VAL B 2 29  B -6.25607  -2.99332  37.85823  1.000 23.02174  ? 27  VAL L HG12 1 
ATOM   3613 H HG13 . VAL B 2 29  B -7.03369  -1.75838  38.48571  1.000 23.02174  ? 27  VAL L HG13 1 
ATOM   3614 H HG21 . VAL B 2 29  B -4.84410  -1.43656  40.61848  1.000 24.15819  ? 27  VAL L HG21 1 
ATOM   3615 H HG22 . VAL B 2 29  B -6.36450  -1.20299  41.01513  1.000 24.15819  ? 27  VAL L HG22 1 
ATOM   3616 H HG23 . VAL B 2 29  B -5.50511  -2.30171  41.77524  1.000 24.15819  ? 27  VAL L HG23 1 
ATOM   3617 N N    . TRP B 2 30  ? -6.43958  -5.34778  41.64423  1.000 16.56665  ? 28  TRP L N    1 
ATOM   3618 C CA   . TRP B 2 30  ? -6.20793  -6.16078  42.83081  1.000 16.16359  ? 28  TRP L CA   1 
ATOM   3619 C C    . TRP B 2 30  ? -5.70506  -5.31441  43.99292  1.000 19.97000  ? 28  TRP L C    1 
ATOM   3620 O O    . TRP B 2 30  ? -4.72859  -4.56936  43.86121  1.000 18.54510  ? 28  TRP L O    1 
ATOM   3621 C CB   . TRP B 2 30  ? -5.19935  -7.25994  42.49817  1.000 17.61453  ? 28  TRP L CB   1 
ATOM   3622 C CG   . TRP B 2 30  ? -4.91622  -8.21510  43.61564  1.000 15.40961  ? 28  TRP L CG   1 
ATOM   3623 C CD1  . TRP B 2 30  ? -3.74902  -8.33961  44.31126  1.000 16.88390  ? 28  TRP L CD1  1 
ATOM   3624 C CD2  . TRP B 2 30  ? -5.81514  -9.18950  44.16109  1.000 16.32818  ? 28  TRP L CD2  1 
ATOM   3625 N NE1  . TRP B 2 30  ? -3.86680  -9.33453  45.25561  1.000 15.52304  ? 28  TRP L NE1  1 
ATOM   3626 C CE2  . TRP B 2 30  ? -5.12559  -9.86597  45.18758  1.000 17.06778  ? 28  TRP L CE2  1 
ATOM   3627 C CE3  . TRP B 2 30  ? -7.13598  -9.55061  43.88507  1.000 14.75638  ? 28  TRP L CE3  1 
ATOM   3628 C CZ2  . TRP B 2 30  ? -5.71239  -10.88146 45.93306  1.000 16.43982  ? 28  TRP L CZ2  1 
ATOM   3629 C CZ3  . TRP B 2 30  ? -7.71409  -10.55937 44.62726  1.000 20.67954  ? 28  TRP L CZ3  1 
ATOM   3630 C CH2  . TRP B 2 30  ? -7.00106  -11.21736 45.63268  1.000 18.40262  ? 28  TRP L CH2  1 
ATOM   3631 H H    . TRP B 2 30  ? -6.00774  -5.61889  40.95169  1.000 19.88681  ? 28  TRP L H    1 
ATOM   3632 H HA   . TRP B 2 30  ? -7.04291  -6.56844  43.10925  1.000 19.40314  ? 28  TRP L HA   1 
ATOM   3633 H HB2  . TRP B 2 30  ? -5.54296  -7.77730  41.75308  1.000 21.14427  ? 28  TRP L HB2  1 
ATOM   3634 H HB3  . TRP B 2 30  ? -4.35912  -6.84214  42.25248  1.000 21.14427  ? 28  TRP L HB3  1 
ATOM   3635 H HD1  . TRP B 2 30  ? -2.98592  -7.82758  44.16846  1.000 20.26751  ? 28  TRP L HD1  1 
ATOM   3636 H HE1  . TRP B 2 30  ? -3.24893  -9.58194  45.80024  1.000 18.63448  ? 28  TRP L HE1  1 
ATOM   3637 H HE3  . TRP B 2 30  ? -7.61564  -9.11984  43.21480  1.000 17.71450  ? 28  TRP L HE3  1 
ATOM   3638 H HZ2  . TRP B 2 30  ? -5.24538  -11.31533 46.61023  1.000 19.73462  ? 28  TRP L HZ2  1 
ATOM   3639 H HZ3  . TRP B 2 30  ? -8.59418  -10.80594 44.45539  1.000 24.82228  ? 28  TRP L HZ3  1 
ATOM   3640 H HH2  . TRP B 2 30  ? -7.41446  -11.90087 46.10892  1.000 22.08998  ? 28  TRP L HH2  1 
ATOM   3641 N N    . ARG B 2 31  ? -6.38787  -5.43246  45.13723  1.000 19.73454  ? 29  ARG L N    1 
ATOM   3642 C CA   . ARG B 2 31  ? -6.06081  -4.71993  46.37130  1.000 24.09051  ? 29  ARG L CA   1 
ATOM   3643 C C    . ARG B 2 31  ? -6.05436  -3.20249  46.20008  1.000 22.97162  ? 29  ARG L C    1 
ATOM   3644 O O    . ARG B 2 31  ? -5.51133  -2.48909  47.04718  1.000 23.76847  ? 29  ARG L O    1 
ATOM   3645 C CB   . ARG B 2 31  ? -4.70751  -5.17313  46.93038  1.000 24.83862  ? 29  ARG L CB   1 
ATOM   3646 C CG   . ARG B 2 31  ? -4.66774  -6.62935  47.35197  1.000 32.67776  ? 29  ARG L CG   1 
ATOM   3647 C CD   . ARG B 2 31  ? -3.26671  -7.04074  47.78614  1.000 42.48534  ? 29  ARG L CD   1 
ATOM   3648 N NE   . ARG B 2 31  ? -3.09655  -7.03642  49.23671  1.000 58.08079  ? 29  ARG L NE   1 
ATOM   3649 C CZ   . ARG B 2 31  ? -2.53614  -6.05820  49.93898  1.000 54.53506  ? 29  ARG L CZ   1 
ATOM   3650 N NH1  . ARG B 2 31  ? -2.07976  -4.95802  49.36028  1.000 58.44724  ? 29  ARG L NH1  1 
ATOM   3651 N NH2  . ARG B 2 31  ? -2.42831  -6.18904  51.25756  1.000 62.45146  ? 29  ARG L NH2  1 
ATOM   3652 H H    . ARG B 2 31  ? -7.07457  -5.94288  45.22387  1.000 23.68828  ? 29  ARG L H    1 
ATOM   3653 H HA   . ARG B 2 31  ? -6.75214  -4.93353  47.01732  1.000 28.91545  ? 29  ARG L HA   1 
ATOM   3654 H HB2  . ARG B 2 31  ? -4.03093  -5.04563  46.24708  1.000 29.81318  ? 29  ARG L HB2  1 
ATOM   3655 H HB3  . ARG B 2 31  ? -4.49760  -4.63495  47.70961  1.000 29.81318  ? 29  ARG L HB3  1 
ATOM   3656 H HG2  . ARG B 2 31  ? -5.27162  -6.76517  48.09883  1.000 39.22015  ? 29  ARG L HG2  1 
ATOM   3657 H HG3  . ARG B 2 31  ? -4.93297  -7.18841  46.60497  1.000 39.22015  ? 29  ARG L HG3  1 
ATOM   3658 H HD2  . ARG B 2 31  ? -3.08831  -7.93912  47.46677  1.000 50.98924  ? 29  ARG L HD2  1 
ATOM   3659 H HD3  . ARG B 2 31  ? -2.62409  -6.42043  47.40779  1.000 50.98924  ? 29  ARG L HD3  1 
ATOM   3660 H HE   . ARG B 2 31  ? -3.38194  -7.72184  49.67071  1.000 69.70378  ? 29  ARG L HE   1 
ATOM   3661 H HH11 . ARG B 2 31  ? -2.14227  -4.86292  48.50785  1.000 70.14352  ? 29  ARG L HH11 1 
ATOM   3662 H HH12 . ARG B 2 31  ? -1.72087  -4.33864  49.83689  1.000 70.14352  ? 29  ARG L HH12 1 
ATOM   3663 H HH21 . ARG B 2 31  ? -2.71942  -6.89984  51.64437  1.000 74.94859  ? 29  ARG L HH21 1 
ATOM   3664 H HH22 . ARG B 2 31  ? -2.06744  -5.56289  51.72373  1.000 74.94859  ? 29  ARG L HH22 1 
ATOM   3665 N N    . ASN B 2 32  ? -6.65380  -2.69636  45.12342  1.000 18.08247  ? 30  ASN L N    1 
ATOM   3666 C CA   . ASN B 2 32  ? -6.57906  -1.27859  44.76305  1.000 20.07563  ? 30  ASN L CA   1 
ATOM   3667 C C    . ASN B 2 32  ? -5.13601  -0.79945  44.65148  1.000 29.24705  ? 30  ASN L C    1 
ATOM   3668 O O    . ASN B 2 32  ? -4.84449  0.37865   44.87105  1.000 27.47989  ? 30  ASN L O    1 
ATOM   3669 C CB   . ASN B 2 32  ? -7.34928  -0.41109  45.75960  1.000 25.54671  ? 30  ASN L CB   1 
ATOM   3670 C CG   . ASN B 2 32  ? -8.80930  -0.77096  45.82061  1.000 31.22419  ? 30  ASN L CG   1 
ATOM   3671 O OD1  . ASN B 2 32  ? -9.50460  -0.77817  44.80147  1.000 32.25460  ? 30  ASN L OD1  1 
ATOM   3672 N ND2  . ASN B 2 32  ? -9.28275  -1.10111  47.01373  1.000 38.64715  ? 30  ASN L ND2  1 
ATOM   3673 H H    . ASN B 2 32  ? -7.12074  -3.16317  44.57237  1.000 21.70580  ? 30  ASN L H    1 
ATOM   3674 H HA   . ASN B 2 32  ? -6.98948  -1.17445  43.89035  1.000 24.09759  ? 30  ASN L HA   1 
ATOM   3675 H HB2  . ASN B 2 32  ? -6.97133  -0.53192  46.64472  1.000 30.66288  ? 30  ASN L HB2  1 
ATOM   3676 H HB3  . ASN B 2 32  ? -7.27845  0.51878   45.49271  1.000 30.66288  ? 30  ASN L HB3  1 
ATOM   3677 H HD21 . ASN B 2 32  ? -10.11081 -1.31525  47.10355  1.000 46.38342  ? 30  ASN L HD21 1 
ATOM   3678 H HD22 . ASN B 2 32  ? -8.76191  -1.10118  47.69807  1.000 46.38342  ? 30  ASN L HD22 1 
ATOM   3679 N N    . LYS B 2 33  ? -4.21985  -1.70088  44.28732  1.000 22.14117  ? 31  LYS L N    1 
ATOM   3680 C CA   . LYS B 2 33  ? -2.80708  -1.34585  44.25678  1.000 20.67205  ? 31  LYS L CA   1 
ATOM   3681 C C    . LYS B 2 33  ? -2.08794  -1.81619  43.00075  1.000 19.87469  ? 31  LYS L C    1 
ATOM   3682 O O    . LYS B 2 33  ? -1.12333  -1.17863  42.56817  1.000 20.40773  ? 31  LYS L O    1 
ATOM   3683 C CB   . LYS B 2 33  ? -2.10507  -1.90990  45.49926  1.000 31.82723  ? 31  LYS L CB   1 
ATOM   3684 C CG   . LYS B 2 33  ? -2.57246  -1.23392  46.77975  1.000 51.26805  ? 31  LYS L CG   1 
ATOM   3685 C CD   . LYS B 2 33  ? -1.70402  -1.54627  47.99085  1.000 59.45955  ? 31  LYS L CD   1 
ATOM   3686 C CE   . LYS B 2 33  ? -1.82256  -0.43857  49.04214  1.000 65.95603  ? 31  LYS L CE   1 
ATOM   3687 N NZ   . LYS B 2 33  ? -3.13196  0.29279   48.97943  1.000 69.04744  ? 31  LYS L NZ   1 
ATOM   3688 H H    . LYS B 2 33  ? -4.39256  -2.51145  44.05761  1.000 26.57624  ? 31  LYS L H    1 
ATOM   3689 H HA   . LYS B 2 33  ? -2.75166  -0.37744  44.25418  1.000 24.81329  ? 31  LYS L HA   1 
ATOM   3690 H HB2  . LYS B 2 33  ? -2.29712  -2.85807  45.56989  1.000 38.19951  ? 31  LYS L HB2  1 
ATOM   3691 H HB3  . LYS B 2 33  ? -1.14886  -1.77047  45.41486  1.000 38.19951  ? 31  LYS L HB3  1 
ATOM   3692 H HG2  . LYS B 2 33  ? -2.56089  -0.27296  46.64813  1.000 61.52849  ? 31  LYS L HG2  1 
ATOM   3693 H HG3  . LYS B 2 33  ? -3.47426  -1.53070  46.97871  1.000 61.52849  ? 31  LYS L HG3  1 
ATOM   3694 H HD2  . LYS B 2 33  ? -1.99238  -2.38205  48.38987  1.000 71.35829  ? 31  LYS L HD2  1 
ATOM   3695 H HD3  . LYS B 2 33  ? -0.77609  -1.61251  47.71618  1.000 71.35829  ? 31  LYS L HD3  1 
ATOM   3696 H HE2  . LYS B 2 33  ? -1.74233  -0.83203  49.92512  1.000 79.15407  ? 31  LYS L HE2  1 
ATOM   3697 H HE3  . LYS B 2 33  ? -1.11276  0.20731   48.90099  1.000 79.15407  ? 31  LYS L HE3  1 
ATOM   3698 H HZ1  . LYS B 2 33  ? -3.24985  0.77011   49.72130  1.000 82.86376  ? 31  LYS L HZ1  1 
ATOM   3699 H HZ2  . LYS B 2 33  ? -3.14100  0.84129   48.27859  1.000 82.86376  ? 31  LYS L HZ2  1 
ATOM   3700 H HZ3  . LYS B 2 33  ? -3.80159  -0.28809  48.90025  1.000 82.86376  ? 31  LYS L HZ3  1 
ATOM   3701 N N    . ASN B 2 34  ? -2.53815  -2.91103  42.39158  1.000 17.82668  ? 32  ASN L N    1 
ATOM   3702 C CA   . ASN B 2 34  ? -1.74154  -3.56773  41.35265  1.000 16.04204  ? 32  ASN L CA   1 
ATOM   3703 C C    . ASN B 2 34  ? -1.95936  -2.90113  39.99953  1.000 15.91814  ? 32  ASN L C    1 
ATOM   3704 O O    . ASN B 2 34  ? -2.74917  -3.35039  39.17159  1.000 15.75606  ? 32  ASN L O    1 
ATOM   3705 C CB   . ASN B 2 34  ? -2.07430  -5.05215  41.28324  1.000 15.06263  ? 32  ASN L CB   1 
ATOM   3706 C CG   . ASN B 2 34  ? -1.50767  -5.82032  42.45070  1.000 16.32711  ? 32  ASN L CG   1 
ATOM   3707 O OD1  . ASN B 2 34  ? -1.64767  -5.41205  43.59870  1.000 18.85219  ? 32  ASN L OD1  1 
ATOM   3708 N ND2  . ASN B 2 34  ? -0.82938  -6.92516  42.16140  1.000 18.65738  ? 32  ASN L ND2  1 
ATOM   3709 H H    . ASN B 2 34  ? -3.29218  -3.28911  42.55918  1.000 21.39885  ? 32  ASN L H    1 
ATOM   3710 H HA   . ASN B 2 34  ? -0.80777  -3.44965  41.58723  1.000 19.25728  ? 32  ASN L HA   1 
ATOM   3711 H HB2  . ASN B 2 34  ? -3.03799  -5.16251  41.28831  1.000 18.08199  ? 32  ASN L HB2  1 
ATOM   3712 H HB3  . ASN B 2 34  ? -1.70212  -5.42362  40.46813  1.000 18.08199  ? 32  ASN L HB3  1 
ATOM   3713 H HD21 . ASN B 2 34  ? -0.48699  -7.39741  42.79334  1.000 22.39569  ? 32  ASN L HD21 1 
ATOM   3714 H HD22 . ASN B 2 34  ? -0.73263  -7.16823  41.34216  1.000 22.39569  ? 32  ASN L HD22 1 
ATOM   3715 N N    . VAL B 2 35  ? -1.21297  -1.82315  39.76363  1.000 13.99864  ? 33  VAL L N    1 
ATOM   3716 C CA   . VAL B 2 35  ? -1.10252  -1.23078  38.43441  1.000 16.35423  ? 33  VAL L CA   1 
ATOM   3717 C C    . VAL B 2 35  ? 0.33357   -0.79214  38.21757  1.000 15.21528  ? 33  VAL L C    1 
ATOM   3718 O O    . VAL B 2 35  ? 0.97498   -0.22919  39.11340  1.000 14.93695  ? 33  VAL L O    1 
ATOM   3719 C CB   . VAL B 2 35  ? -2.07159  -0.04736  38.22594  1.000 21.74822  ? 33  VAL L CB   1 
ATOM   3720 C CG1  . VAL B 2 35  ? -1.99242  0.88761   39.36892  1.000 22.75860  ? 33  VAL L CG1  1 
ATOM   3721 C CG2  . VAL B 2 35  ? -1.74965  0.68626   36.92637  1.000 26.33132  ? 33  VAL L CG2  1 
ATOM   3722 H H    . VAL B 2 35  ? -0.75614  -1.41308  40.36592  1.000 16.80521  ? 33  VAL L H    1 
ATOM   3723 H HA   . VAL B 2 35  ? -1.32379  -1.90982  37.77802  1.000 19.63191  ? 33  VAL L HA   1 
ATOM   3724 H HB   . VAL B 2 35  ? -2.97660  -0.39155  38.16775  1.000 26.10469  ? 33  VAL L HB   1 
ATOM   3725 H HG11 . VAL B 2 35  ? -2.42710  1.72020   39.12654  1.000 27.31716  ? 33  VAL L HG11 1 
ATOM   3726 H HG12 . VAL B 2 35  ? -2.43974  0.49109   40.13284  1.000 27.31716  ? 33  VAL L HG12 1 
ATOM   3727 H HG13 . VAL B 2 35  ? -1.05970  1.05053   39.57963  1.000 27.31716  ? 33  VAL L HG13 1 
ATOM   3728 H HG21 . VAL B 2 35  ? -2.49756  1.25813   36.69293  1.000 31.60442  ? 33  VAL L HG21 1 
ATOM   3729 H HG22 . VAL B 2 35  ? -0.95136  1.22194   37.05554  1.000 31.60442  ? 33  VAL L HG22 1 
ATOM   3730 H HG23 . VAL B 2 35  ? -1.60024  0.03397   36.22417  1.000 31.60442  ? 33  VAL L HG23 1 
ATOM   3731 N N    . ALA B 2 36  ? 0.83823   -1.06833  37.02644  1.000 14.07931  ? 34  ALA L N    1 
ATOM   3732 C CA   . ALA B 2 36  ? 2.17020   -0.66946  36.61673  1.000 13.45727  ? 34  ALA L CA   1 
ATOM   3733 C C    . ALA B 2 36  ? 2.09581   0.17445   35.35428  1.000 15.94818  ? 34  ALA L C    1 
ATOM   3734 O O    . ALA B 2 36  ? 1.15285   0.06384   34.56324  1.000 16.62184  ? 34  ALA L O    1 
ATOM   3735 C CB   . ALA B 2 36  ? 3.05056   -1.88239  36.36296  1.000 12.42453  ? 34  ALA L CB   1 
ATOM   3736 H H    . ALA B 2 36  ? 0.41187   -1.50117  36.41779  1.000 16.90200  ? 34  ALA L H    1 
ATOM   3737 H HA   . ALA B 2 36  ? 2.57534   -0.13430  37.31699  1.000 16.15556  ? 34  ALA L HA   1 
ATOM   3738 H HB1  . ALA B 2 36  ? 3.89424   -1.58701  35.98635  1.000 14.91627  ? 34  ALA L HB1  1 
ATOM   3739 H HB2  . ALA B 2 36  ? 3.20602   -2.34115  37.20336  1.000 14.91627  ? 34  ALA L HB2  1 
ATOM   3740 H HB3  . ALA B 2 36  ? 2.60010   -2.47498  35.74102  1.000 14.91627  ? 34  ALA L HB3  1 
ATOM   3741 N N    . TRP B 2 37  ? 3.09478   1.03127   35.18779  1.000 15.72426  ? 35  TRP L N    1 
ATOM   3742 C CA   . TRP B 2 37  ? 3.31375   1.75248   33.94227  1.000 13.86077  ? 35  TRP L CA   1 
ATOM   3743 C C    . TRP B 2 37  ? 4.57395   1.21860   33.28357  1.000 13.41460  ? 35  TRP L C    1 
ATOM   3744 O O    . TRP B 2 37  ? 5.63506   1.12806   33.93301  1.000 15.37803  ? 35  TRP L O    1 
ATOM   3745 C CB   . TRP B 2 37  ? 3.44767   3.25490   34.16519  1.000 13.91092  ? 35  TRP L CB   1 
ATOM   3746 C CG   . TRP B 2 37  ? 2.15010   3.91983   34.49758  1.000 13.18133  ? 35  TRP L CG   1 
ATOM   3747 C CD1  . TRP B 2 37  ? 1.66197   4.19332   35.73961  1.000 15.35674  ? 35  TRP L CD1  1 
ATOM   3748 C CD2  . TRP B 2 37  ? 1.16441   4.38100   33.56770  1.000 14.84866  ? 35  TRP L CD2  1 
ATOM   3749 N NE1  . TRP B 2 37  ? 0.43145   4.80543   35.64028  1.000 14.37967  ? 35  TRP L NE1  1 
ATOM   3750 C CE2  . TRP B 2 37  ? 0.10623   4.92987   34.31610  1.000 16.71434  ? 35  TRP L CE2  1 
ATOM   3751 C CE3  . TRP B 2 37  ? 1.08231   4.39502   32.17361  1.000 15.17379  ? 35  TRP L CE3  1 
ATOM   3752 C CZ2  . TRP B 2 37  ? -1.01920  5.48456   33.71707  1.000 15.58534  ? 35  TRP L CZ2  1 
ATOM   3753 C CZ3  . TRP B 2 37  ? -0.03815  4.93503   31.58278  1.000 14.61699  ? 35  TRP L CZ3  1 
ATOM   3754 C CH2  . TRP B 2 37  ? -1.06911  5.48160   32.35153  1.000 15.48896  ? 35  TRP L CH2  1 
ATOM   3755 H H    . TRP B 2 37  ? 3.67282   1.21567   35.79727  1.000 18.87594  ? 35  TRP L H    1 
ATOM   3756 H HA   . TRP B 2 37  ? 2.55434   1.60796   33.35634  1.000 16.63976  ? 35  TRP L HA   1 
ATOM   3757 H HB2  . TRP B 2 37  ? 4.05943   3.40972   34.90186  1.000 16.69994  ? 35  TRP L HB2  1 
ATOM   3758 H HB3  . TRP B 2 37  ? 3.79309   3.66286   33.35577  1.000 16.69994  ? 35  TRP L HB3  1 
ATOM   3759 H HD1  . TRP B 2 37  ? 2.09592   3.99574   36.53807  1.000 18.43492  ? 35  TRP L HD1  1 
ATOM   3760 H HE1  . TRP B 2 37  ? -0.05272  5.06641   36.30139  1.000 17.26243  ? 35  TRP L HE1  1 
ATOM   3761 H HE3  . TRP B 2 37  ? 1.77080   4.04652   31.65454  1.000 18.21538  ? 35  TRP L HE3  1 
ATOM   3762 H HZ2  . TRP B 2 37  ? -1.71042  5.84326   34.22546  1.000 18.70925  ? 35  TRP L HZ2  1 
ATOM   3763 H HZ3  . TRP B 2 37  ? -0.11002  4.93600   30.65556  1.000 17.54723  ? 35  TRP L HZ3  1 
ATOM   3764 H HH2  . TRP B 2 37  ? -1.80691  5.85224   31.92354  1.000 18.59358  ? 35  TRP L HH2  1 
ATOM   3765 N N    . TYR B 2 38  ? 4.44043   0.90671   31.99310  1.000 14.78874  ? 36  TYR L N    1 
ATOM   3766 C CA   . TYR B 2 38  ? 5.47537   0.33772   31.15123  1.000 11.14802  ? 36  TYR L CA   1 
ATOM   3767 C C    . TYR B 2 38  ? 5.78032   1.24860   29.97053  1.000 13.94719  ? 36  TYR L C    1 
ATOM   3768 O O    . TYR B 2 38  ? 4.90396   1.95085   29.45612  1.000 13.04378  ? 36  TYR L O    1 
ATOM   3769 C CB   . TYR B 2 38  ? 5.04100   -1.01144  30.60701  1.000 12.27445  ? 36  TYR L CB   1 
ATOM   3770 C CG   . TYR B 2 38  ? 5.37087   -2.17367  31.48718  1.000 11.87860  ? 36  TYR L CG   1 
ATOM   3771 C CD1  . TYR B 2 38  ? 4.51009   -2.58239  32.49699  1.000 13.49813  ? 36  TYR L CD1  1 
ATOM   3772 C CD2  . TYR B 2 38  ? 6.54739   -2.87747  31.30059  1.000 13.19245  ? 36  TYR L CD2  1 
ATOM   3773 C CE1  . TYR B 2 38  ? 4.82756   -3.66383  33.29841  1.000 15.15152  ? 36  TYR L CE1  1 
ATOM   3774 C CE2  . TYR B 2 38  ? 6.86625   -3.93923  32.08595  1.000 16.43612  ? 36  TYR L CE2  1 
ATOM   3775 C CZ   . TYR B 2 38  ? 6.00980   -4.33334  33.08060  1.000 13.58861  ? 36  TYR L CZ   1 
ATOM   3776 O OH   . TYR B 2 38  ? 6.37033   -5.40872  33.84443  1.000 15.93377  ? 36  TYR L OH   1 
ATOM   3777 H H    . TYR B 2 38  ? 3.70712   1.02632   31.56002  1.000 17.75333  ? 36  TYR L H    1 
ATOM   3778 H HA   . TYR B 2 38  ? 6.28366   0.24015   31.67853  1.000 13.38446  ? 36  TYR L HA   1 
ATOM   3779 H HB2  . TYR B 2 38  ? 4.07861   -1.00002  30.48628  1.000 14.73617  ? 36  TYR L HB2  1 
ATOM   3780 H HB3  . TYR B 2 38  ? 5.48060   -1.15624  29.75455  1.000 14.73617  ? 36  TYR L HB3  1 
ATOM   3781 H HD1  . TYR B 2 38  ? 3.71254   -2.12463  32.63575  1.000 16.20459  ? 36  TYR L HD1  1 
ATOM   3782 H HD2  . TYR B 2 38  ? 7.13122   -2.61872  30.62451  1.000 15.83778  ? 36  TYR L HD2  1 
ATOM   3783 H HE1  . TYR B 2 38  ? 4.25004   -3.93478  33.97514  1.000 18.18865  ? 36  TYR L HE1  1 
ATOM   3784 H HE2  . TYR B 2 38  ? 7.66381   -4.39750  31.94890  1.000 19.73017  ? 36  TYR L HE2  1 
ATOM   3785 H HH   . TYR B 2 38  ? 5.77764   -5.56472  34.41887  1.000 19.12736  ? 36  TYR L HH   1 
ATOM   3786 N N    . GLN B 2 39  ? 7.02077   1.16426   29.50625  1.000 14.98155  ? 37  GLN L N    1 
ATOM   3787 C CA   . GLN B 2 39  ? 7.51995   1.92870   28.37263  1.000 13.00060  ? 37  GLN L CA   1 
ATOM   3788 C C    . GLN B 2 39  ? 8.09319   0.95141   27.35929  1.000 13.10740  ? 37  GLN L C    1 
ATOM   3789 O O    . GLN B 2 39  ? 8.99564   0.17848   27.69439  1.000 16.45965  ? 37  GLN L O    1 
ATOM   3790 C CB   . GLN B 2 39  ? 8.58408   2.91520   28.85191  1.000 14.76761  ? 37  GLN L CB   1 
ATOM   3791 C CG   . GLN B 2 39  ? 9.26217   3.73719   27.79155  1.000 14.72777  ? 37  GLN L CG   1 
ATOM   3792 C CD   . GLN B 2 39  ? 10.56805  4.32112   28.29800  1.000 20.89866  ? 37  GLN L CD   1 
ATOM   3793 O OE1  . GLN B 2 39  ? 11.53505  3.59128   28.51927  1.000 22.85836  ? 37  GLN L OE1  1 
ATOM   3794 N NE2  . GLN B 2 39  ? 10.60020  5.63619   28.49624  1.000 19.67997  ? 37  GLN L NE2  1 
ATOM   3795 H H    . GLN B 2 39  ? 7.61800   0.64776   29.84705  1.000 17.98469  ? 37  GLN L H    1 
ATOM   3796 H HA   . GLN B 2 39  ? 6.80552   2.42164   27.93962  1.000 15.60756  ? 37  GLN L HA   1 
ATOM   3797 H HB2  . GLN B 2 39  ? 8.16388   3.53589   29.46760  1.000 17.72797  ? 37  GLN L HB2  1 
ATOM   3798 H HB3  . GLN B 2 39  ? 9.27677   2.41268   29.30858  1.000 17.72797  ? 37  GLN L HB3  1 
ATOM   3799 H HG2  . GLN B 2 39  ? 9.45493   3.17633   27.02397  1.000 17.68015  ? 37  GLN L HG2  1 
ATOM   3800 H HG3  . GLN B 2 39  ? 8.68073   4.46840   27.53049  1.000 17.68015  ? 37  GLN L HG3  1 
ATOM   3801 H HE21 . GLN B 2 39  ? 9.90162   6.11212   28.33791  1.000 23.62280  ? 37  GLN L HE21 1 
ATOM   3802 H HE22 . GLN B 2 39  ? 11.31957  6.01040   28.78274  1.000 23.62280  ? 37  GLN L HE22 1 
ATOM   3803 N N    . GLN B 2 40  ? 7.58920   0.98085   26.12274  1.000 12.16448  ? 38  GLN L N    1 
ATOM   3804 C CA   . GLN B 2 40  ? 8.04197   0.05701   25.08993  1.000 17.30173  ? 38  GLN L CA   1 
ATOM   3805 C C    . GLN B 2 40  ? 8.59715   0.82760   23.90134  1.000 18.85906  ? 38  GLN L C    1 
ATOM   3806 O O    . GLN B 2 40  ? 7.89924   1.65976   23.30927  1.000 15.58823  ? 38  GLN L O    1 
ATOM   3807 C CB   . GLN B 2 40  ? 6.92228   -0.87739  24.61814  1.000 17.62709  ? 38  GLN L CB   1 
ATOM   3808 C CG   . GLN B 2 40  ? 7.46845   -2.00888  23.74450  1.000 16.37597  ? 38  GLN L CG   1 
ATOM   3809 C CD   . GLN B 2 40  ? 6.39818   -2.89737  23.12940  1.000 19.90639  ? 38  GLN L CD   1 
ATOM   3810 O OE1  . GLN B 2 40  ? 5.26973   -2.46679  22.88510  1.000 18.95509  ? 38  GLN L OE1  1 
ATOM   3811 N NE2  . GLN B 2 40  ? 6.75391   -4.15115  22.87988  1.000 19.20979  ? 38  GLN L NE2  1 
ATOM   3812 H H    . GLN B 2 40  ? 6.98183   1.53079   25.86148  1.000 14.60420  ? 38  GLN L H    1 
ATOM   3813 H HA   . GLN B 2 40  ? 8.75589   -0.47706  25.47200  1.000 20.76890  ? 38  GLN L HA   1 
ATOM   3814 H HB2  . GLN B 2 40  ? 6.48599   -1.27042  25.39020  1.000 21.15934  ? 38  GLN L HB2  1 
ATOM   3815 H HB3  . GLN B 2 40  ? 6.28034   -0.37077  24.09647  1.000 21.15934  ? 38  GLN L HB3  1 
ATOM   3816 H HG2  . GLN B 2 40  ? 7.98022   -1.62024  23.01790  1.000 19.65799  ? 38  GLN L HG2  1 
ATOM   3817 H HG3  . GLN B 2 40  ? 8.04035   -2.57247  24.28875  1.000 19.65799  ? 38  GLN L HG3  1 
ATOM   3818 H HE21 . GLN B 2 40  ? 7.55027   -4.41730  23.06582  1.000 23.05858  ? 38  GLN L HE21 1 
ATOM   3819 H HE22 . GLN B 2 40  ? 6.18810   -4.69758  22.53222  1.000 23.05858  ? 38  GLN L HE22 1 
ATOM   3820 N N    . LYS B 2 41  ? 9.85120   0.55287   23.56676  1.000 22.31633  ? 39  LYS L N    1 
ATOM   3821 C CA   . LYS B 2 41  ? 10.41783  0.92162   22.28103  1.000 24.12422  ? 39  LYS L CA   1 
ATOM   3822 C C    . LYS B 2 41  ? 10.04131  -0.13369  21.24129  1.000 29.82219  ? 39  LYS L C    1 
ATOM   3823 O O    . LYS B 2 41  ? 9.93327   -1.31874  21.56717  1.000 30.43897  ? 39  LYS L O    1 
ATOM   3824 C CB   . LYS B 2 41  ? 11.93163  1.02329   22.37478  1.000 26.76729  ? 39  LYS L CB   1 
ATOM   3825 C CG   . LYS B 2 41  ? 12.43016  1.90790   23.49044  1.000 29.85282  ? 39  LYS L CG   1 
ATOM   3826 C CD   . LYS B 2 41  ? 12.23642  3.36854   23.15464  1.000 34.34647  ? 39  LYS L CD   1 
ATOM   3827 C CE   . LYS B 2 41  ? 13.00221  4.26681   24.11305  1.000 34.79888  ? 39  LYS L CE   1 
ATOM   3828 N NZ   . LYS B 2 41  ? 13.19683  5.63205   23.53004  1.000 31.99981  ? 39  LYS L NZ   1 
ATOM   3829 H H    . LYS B 2 41  ? 10.40728  0.14380   24.07963  1.000 26.78643  ? 39  LYS L H    1 
ATOM   3830 H HA   . LYS B 2 41  ? 10.07767  1.78556   22.00032  1.000 28.95590  ? 39  LYS L HA   1 
ATOM   3831 H HB2  . LYS B 2 41  ? 12.29259  0.13497   22.52140  1.000 32.12759  ? 39  LYS L HB2  1 
ATOM   3832 H HB3  . LYS B 2 41  ? 12.26938  1.38509   21.54056  1.000 32.12759  ? 39  LYS L HB3  1 
ATOM   3833 H HG2  . LYS B 2 41  ? 11.93712  1.71207   24.30252  1.000 35.83022  ? 39  LYS L HG2  1 
ATOM   3834 H HG3  . LYS B 2 41  ? 13.37668  1.74849   23.63039  1.000 35.83022  ? 39  LYS L HG3  1 
ATOM   3835 H HD2  . LYS B 2 41  ? 12.55882  3.53703   22.25543  1.000 41.22259  ? 39  LYS L HD2  1 
ATOM   3836 H HD3  . LYS B 2 41  ? 11.29408  3.59016   23.21618  1.000 41.22259  ? 39  LYS L HD3  1 
ATOM   3837 H HE2  . LYS B 2 41  ? 12.50437  4.35458   24.94091  1.000 41.76549  ? 39  LYS L HE2  1 
ATOM   3838 H HE3  . LYS B 2 41  ? 13.87454  3.88120   24.28979  1.000 41.76549  ? 39  LYS L HE3  1 
ATOM   3839 H HZ1  . LYS B 2 41  ? 13.68528  5.57933   22.78792  1.000 38.40660  ? 39  LYS L HZ1  1 
ATOM   3840 H HZ2  . LYS B 2 41  ? 12.40814  5.99359   23.33166  1.000 38.40660  ? 39  LYS L HZ2  1 
ATOM   3841 H HZ3  . LYS B 2 41  ? 13.61579  6.15593   24.11496  1.000 38.40660  ? 39  LYS L HZ3  1 
ATOM   3842 N N    . PRO B 2 42  ? 9.84913   0.26339   19.98407  1.000 34.75247  ? 40  PRO L N    1 
ATOM   3843 C CA   . PRO B 2 42  ? 9.28210   -0.67019  18.99671  1.000 43.91773  ? 40  PRO L CA   1 
ATOM   3844 C C    . PRO B 2 42  ? 10.10110  -1.94909  18.87078  1.000 42.65793  ? 40  PRO L C    1 
ATOM   3845 O O    . PRO B 2 42  ? 11.32418  -1.91528  18.71521  1.000 35.64861  ? 40  PRO L O    1 
ATOM   3846 C CB   . PRO B 2 42  ? 9.28465   0.13998   17.69189  1.000 40.04942  ? 40  PRO L CB   1 
ATOM   3847 C CG   . PRO B 2 42  ? 10.20303  1.29759   17.93574  1.000 46.09638  ? 40  PRO L CG   1 
ATOM   3848 C CD   . PRO B 2 42  ? 10.13392  1.58543   19.40146  1.000 41.05965  ? 40  PRO L CD   1 
ATOM   3849 H HA   . PRO B 2 42  ? 8.37249   -0.89947  19.24357  1.000 52.70811  ? 40  PRO L HA   1 
ATOM   3850 H HB2  . PRO B 2 42  ? 9.61170   -0.41209  16.96445  1.000 48.06614  ? 40  PRO L HB2  1 
ATOM   3851 H HB3  . PRO B 2 42  ? 8.38599   0.44828   17.49626  1.000 48.06614  ? 40  PRO L HB3  1 
ATOM   3852 H HG2  . PRO B 2 42  ? 11.10623  1.05670   17.67670  1.000 55.32249  ? 40  PRO L HG2  1 
ATOM   3853 H HG3  . PRO B 2 42  ? 9.90389   2.06418   17.42216  1.000 55.32249  ? 40  PRO L HG3  1 
ATOM   3854 H HD2  . PRO B 2 42  ? 10.97922  1.93269   19.72669  1.000 49.27842  ? 40  PRO L HD2  1 
ATOM   3855 H HD3  . PRO B 2 42  ? 9.42007   2.21198   19.59833  1.000 49.27842  ? 40  PRO L HD3  1 
ATOM   3856 N N    . GLY B 2 43  ? 9.40509   -3.08826  18.94861  1.000 40.40510  ? 41  GLY L N    1 
ATOM   3857 C CA   . GLY B 2 43  ? 10.01617  -4.39274  18.80839  1.000 40.95134  ? 41  GLY L CA   1 
ATOM   3858 C C    . GLY B 2 43  ? 10.62762  -4.96771  20.06846  1.000 45.43504  ? 41  GLY L C    1 
ATOM   3859 O O    . GLY B 2 43  ? 10.78637  -6.19421  20.15611  1.000 42.25626  ? 41  GLY L O    1 
ATOM   3860 H H    . GLY B 2 43  ? 8.55676   -3.12198  19.08572  1.000 48.49295  ? 41  GLY L H    1 
ATOM   3861 H HA2  . GLY B 2 43  ? 9.34106   -5.01701  18.49950  1.000 49.14844  ? 41  GLY L HA2  1 
ATOM   3862 H HA3  . GLY B 2 43  ? 10.71927  -4.33306  18.14281  1.000 49.14844  ? 41  GLY L HA3  1 
ATOM   3863 N N    . LYS B 2 44  ? 10.96219  -4.13029  21.04992  1.000 39.75934  ? 42  LYS L N    1 
ATOM   3864 C CA   . LYS B 2 44  ? 11.68632  -4.52948  22.24920  1.000 31.11202  ? 42  LYS L CA   1 
ATOM   3865 C C    . LYS B 2 44  ? 10.71913  -4.83021  23.38757  1.000 26.94699  ? 42  LYS L C    1 
ATOM   3866 O O    . LYS B 2 44  ? 9.57157   -4.38174  23.39361  1.000 24.46677  ? 42  LYS L O    1 
ATOM   3867 C CB   . LYS B 2 44  ? 12.66034  -3.43004  22.67967  1.000 29.92554  ? 42  LYS L CB   1 
ATOM   3868 C CG   . LYS B 2 44  ? 13.43451  -2.80189  21.52701  1.000 44.20368  ? 42  LYS L CG   1 
ATOM   3869 C CD   . LYS B 2 44  ? 14.39935  -3.78824  20.87181  1.000 51.25603  ? 42  LYS L CD   1 
ATOM   3870 C CE   . LYS B 2 44  ? 15.79048  -3.72005  21.48762  1.000 57.45268  ? 42  LYS L CE   1 
ATOM   3871 N NZ   . LYS B 2 44  ? 16.84830  -4.08159  20.49723  1.000 65.36693  ? 42  LYS L NZ   1 
ATOM   3872 H H    . LYS B 2 44  ? 10.77140  -3.29177  21.04064  1.000 47.71805  ? 42  LYS L H    1 
ATOM   3873 H HA   . LYS B 2 44  ? 12.19303  -5.33465  22.05990  1.000 37.34126  ? 42  LYS L HA   1 
ATOM   3874 H HB2  . LYS B 2 44  ? 12.15897  -2.72453  23.11761  1.000 35.91749  ? 42  LYS L HB2  1 
ATOM   3875 H HB3  . LYS B 2 44  ? 13.30561  -3.81025  23.29607  1.000 35.91749  ? 42  LYS L HB3  1 
ATOM   3876 H HG2  . LYS B 2 44  ? 12.80848  -2.49832  20.85111  1.000 53.05125  ? 42  LYS L HG2  1 
ATOM   3877 H HG3  . LYS B 2 44  ? 13.95091  -2.05204  21.86161  1.000 53.05125  ? 42  LYS L HG3  1 
ATOM   3878 H HD2  . LYS B 2 44  ? 14.06120  -4.69008  20.98693  1.000 61.51407  ? 42  LYS L HD2  1 
ATOM   3879 H HD3  . LYS B 2 44  ? 14.47585  -3.58065  19.92738  1.000 61.51407  ? 42  LYS L HD3  1 
ATOM   3880 H HE2  . LYS B 2 44  ? 15.95985  -2.81687  21.79822  1.000 68.95005  ? 42  LYS L HE2  1 
ATOM   3881 H HE3  . LYS B 2 44  ? 15.84330  -4.34169  22.23036  1.000 68.95005  ? 42  LYS L HE3  1 
ATOM   3882 H HZ1  . LYS B 2 44  ? 17.65155  -4.02864  20.87681  1.000 78.44715  ? 42  LYS L HZ1  1 
ATOM   3883 H HZ2  . LYS B 2 44  ? 16.72090  -4.91273  20.20553  1.000 78.44715  ? 42  LYS L HZ2  1 
ATOM   3884 H HZ3  . LYS B 2 44  ? 16.81924  -3.52447  19.80378  1.000 78.44715  ? 42  LYS L HZ3  1 
ATOM   3885 N N    . ALA B 2 45  ? 11.19707  -5.60653  24.35484  1.000 17.69506  ? 43  ALA L N    1 
ATOM   3886 C CA   . ALA B 2 45  ? 10.37133  -5.92206  25.50863  1.000 20.80329  ? 43  ALA L CA   1 
ATOM   3887 C C    . ALA B 2 45  ? 10.05369  -4.63926  26.27278  1.000 21.51300  ? 43  ALA L C    1 
ATOM   3888 O O    . ALA B 2 45  ? 10.93432  -3.78391  26.44152  1.000 17.37173  ? 43  ALA L O    1 
ATOM   3889 C CB   . ALA B 2 45  ? 11.07840  -6.91475  26.43220  1.000 19.05166  ? 43  ALA L CB   1 
ATOM   3890 H H    . ALA B 2 45  ? 11.98263  -5.95637  24.36552  1.000 21.24090  ? 43  ALA L H    1 
ATOM   3891 H HA   . ALA B 2 45  ? 9.54232   -6.32869  25.21150  1.000 24.97079  ? 43  ALA L HA   1 
ATOM   3892 H HB1  . ALA B 2 45  ? 10.50234  -7.10809  27.18829  1.000 22.86882  ? 43  ALA L HB1  1 
ATOM   3893 H HB2  . ALA B 2 45  ? 11.26151  -7.72967  25.93897  1.000 22.86882  ? 43  ALA L HB2  1 
ATOM   3894 H HB3  . ALA B 2 45  ? 11.90941  -6.52152  26.74153  1.000 22.86882  ? 43  ALA L HB3  1 
ATOM   3895 N N    . PRO B 2 46  ? 8.81392   -4.46268  26.72991  1.000 18.66667  ? 44  PRO L N    1 
ATOM   3896 C CA   . PRO B 2 46  ? 8.48986   -3.29023  27.54935  1.000 17.37125  ? 44  PRO L CA   1 
ATOM   3897 C C    . PRO B 2 46  ? 9.32369   -3.24690  28.81845  1.000 19.22222  ? 44  PRO L C    1 
ATOM   3898 O O    . PRO B 2 46  ? 9.65708   -4.27588  29.41118  1.000 21.78843  ? 44  PRO L O    1 
ATOM   3899 C CB   . PRO B 2 46  ? 7.00122   -3.47815  27.87099  1.000 16.14412  ? 44  PRO L CB   1 
ATOM   3900 C CG   . PRO B 2 46  ? 6.48450   -4.35078  26.78388  1.000 27.52273  ? 44  PRO L CG   1 
ATOM   3901 C CD   . PRO B 2 46  ? 7.61749   -5.27110  26.43431  1.000 20.77935  ? 44  PRO L CD   1 
ATOM   3902 H HA   . PRO B 2 46  ? 8.61974   -2.47325  27.04283  1.000 20.85234  ? 44  PRO L HA   1 
ATOM   3903 H HB2  . PRO B 2 46  ? 6.90097   -3.90448  28.73649  1.000 19.37978  ? 44  PRO L HB2  1 
ATOM   3904 H HB3  . PRO B 2 46  ? 6.55154   -2.61868  27.87045  1.000 19.37978  ? 44  PRO L HB3  1 
ATOM   3905 H HG2  . PRO B 2 46  ? 5.71809   -4.85302  27.10214  1.000 33.03410  ? 44  PRO L HG2  1 
ATOM   3906 H HG3  . PRO B 2 46  ? 6.23213   -3.80908  26.01983  1.000 33.03410  ? 44  PRO L HG3  1 
ATOM   3907 H HD2  . PRO B 2 46  ? 7.59589   -6.06976  26.98437  1.000 24.94205  ? 44  PRO L HD2  1 
ATOM   3908 H HD3  . PRO B 2 46  ? 7.58809   -5.51387  25.49564  1.000 24.94205  ? 44  PRO L HD3  1 
ATOM   3909 N N    . LYS B 2 47  ? 9.66263   -2.03198  29.22672  1.000 18.83597  ? 45  LYS L N    1 
ATOM   3910 C CA   . LYS B 2 47  ? 10.40249  -1.77859  30.45432  1.000 16.95488  ? 45  LYS L CA   1 
ATOM   3911 C C    . LYS B 2 47  ? 9.47021   -1.13131  31.46903  1.000 17.02286  ? 45  LYS L C    1 
ATOM   3912 O O    . LYS B 2 47  ? 8.77176   -0.16355  31.14585  1.000 13.77332  ? 45  LYS L O    1 
ATOM   3913 C CB   . LYS B 2 47  ? 11.60576  -0.87736  30.18077  1.000 21.18784  ? 45  LYS L CB   1 
ATOM   3914 C CG   . LYS B 2 47  ? 12.74218  -1.58724  29.45412  1.000 35.68354  ? 45  LYS L CG   1 
ATOM   3915 C CD   . LYS B 2 47  ? 13.81159  -0.61375  28.96849  1.000 49.53382  ? 45  LYS L CD   1 
ATOM   3916 C CE   . LYS B 2 47  ? 15.13382  -1.32006  28.70048  1.000 57.67085  ? 45  LYS L CE   1 
ATOM   3917 N NZ   . LYS B 2 47  ? 15.67432  -1.97484  29.92765  1.000 71.15657  ? 45  LYS L NZ   1 
ATOM   3918 H H    . LYS B 2 47  ? 9.46845   -1.31425  28.79455  1.000 22.60999  ? 45  LYS L H    1 
ATOM   3919 H HA   . LYS B 2 47  ? 10.72732  -2.61316  30.82697  1.000 20.35268  ? 45  LYS L HA   1 
ATOM   3920 H HB2  . LYS B 2 47  ? 11.31981  -0.13214  29.62961  1.000 25.43224  ? 45  LYS L HB2  1 
ATOM   3921 H HB3  . LYS B 2 47  ? 11.95122  -0.55118  31.02645  1.000 25.43224  ? 45  LYS L HB3  1 
ATOM   3922 H HG2  . LYS B 2 47  ? 13.16136  -2.21949  30.05864  1.000 42.82708  ? 45  LYS L HG2  1 
ATOM   3923 H HG3  . LYS B 2 47  ? 12.38495  -2.05329  28.68205  1.000 42.82708  ? 45  LYS L HG3  1 
ATOM   3924 H HD2  . LYS B 2 47  ? 13.51604  -0.19796  28.14347  1.000 59.44742  ? 45  LYS L HD2  1 
ATOM   3925 H HD3  . LYS B 2 47  ? 13.96048  0.06366   29.64662  1.000 59.44742  ? 45  LYS L HD3  1 
ATOM   3926 H HE2  . LYS B 2 47  ? 14.99972  -2.00400  28.02583  1.000 69.21186  ? 45  LYS L HE2  1 
ATOM   3927 H HE3  . LYS B 2 47  ? 15.78538  -0.67169  28.39067  1.000 69.21186  ? 45  LYS L HE3  1 
ATOM   3928 H HZ1  . LYS B 2 47  ? 15.64155  -1.40923  30.61403  1.000 85.39471  ? 45  LYS L HZ1  1 
ATOM   3929 H HZ2  . LYS B 2 47  ? 15.19244  -2.69663  30.12493  1.000 85.39471  ? 45  LYS L HZ2  1 
ATOM   3930 H HZ3  . LYS B 2 47  ? 16.51973  -2.21936  29.79499  1.000 85.39471  ? 45  LYS L HZ3  1 
ATOM   3931 N N    . ARG B 2 48  ? 9.45208   -1.66630  32.68843  1.000 13.90415  ? 46  ARG L N    1 
ATOM   3932 C CA   . ARG B 2 48  ? 8.56676   -1.13720  33.71603  1.000 16.67664  ? 46  ARG L CA   1 
ATOM   3933 C C    . ARG B 2 48  ? 9.15588   0.12787   34.33381  1.000 17.90741  ? 46  ARG L C    1 
ATOM   3934 O O    . ARG B 2 48  ? 10.32343  0.15515   34.73084  1.000 21.36401  ? 46  ARG L O    1 
ATOM   3935 C CB   . ARG B 2 48  ? 8.31233   -2.18064  34.79967  1.000 14.63720  ? 46  ARG L CB   1 
ATOM   3936 C CG   . ARG B 2 48  ? 7.22865   -1.76773  35.77102  1.000 16.85256  ? 46  ARG L CG   1 
ATOM   3937 C CD   . ARG B 2 48  ? 7.12231   -2.72490  36.93522  1.000 17.37305  ? 46  ARG L CD   1 
ATOM   3938 N NE   . ARG B 2 48  ? 8.31224   -2.65558  37.77578  1.000 21.20454  ? 46  ARG L NE   1 
ATOM   3939 C CZ   . ARG B 2 48  ? 8.47704   -3.31638  38.91334  1.000 18.86242  ? 46  ARG L CZ   1 
ATOM   3940 N NH1  . ARG B 2 48  ? 7.53065   -4.10340  39.39953  1.000 14.87706  ? 46  ARG L NH1  1 
ATOM   3941 N NH2  . ARG B 2 48  ? 9.61955   -3.17870  39.58157  1.000 23.50363  ? 46  ARG L NH2  1 
ATOM   3942 H H    . ARG B 2 48  ? 9.93865   -2.32912  32.94047  1.000 16.69181  ? 46  ARG L H    1 
ATOM   3943 H HA   . ARG B 2 48  ? 7.71722   -0.90845  33.30755  1.000 20.01880  ? 46  ARG L HA   1 
ATOM   3944 H HB2  . ARG B 2 48  ? 8.03807   -3.01084  34.37962  1.000 17.57148  ? 46  ARG L HB2  1 
ATOM   3945 H HB3  . ARG B 2 48  ? 9.12996   -2.31790  35.30322  1.000 17.57148  ? 46  ARG L HB3  1 
ATOM   3946 H HG2  . ARG B 2 48  ? 7.43148   -0.88602  36.12078  1.000 20.22990  ? 46  ARG L HG2  1 
ATOM   3947 H HG3  . ARG B 2 48  ? 6.37487   -1.75376  35.31084  1.000 20.22990  ? 46  ARG L HG3  1 
ATOM   3948 H HD2  . ARG B 2 48  ? 6.35042   -2.49313  37.47501  1.000 20.85449  ? 46  ARG L HD2  1 
ATOM   3949 H HD3  . ARG B 2 48  ? 7.03372   -3.63139  36.60158  1.000 20.85449  ? 46  ARG L HD3  1 
ATOM   3950 H HE   . ARG B 2 48  ? 8.95520   -2.14802  37.51389  1.000 25.45228  ? 46  ARG L HE   1 
ATOM   3951 H HH11 . ARG B 2 48  ? 6.78800   -4.19526  38.97570  1.000 17.85930  ? 46  ARG L HH11 1 
ATOM   3952 H HH12 . ARG B 2 48  ? 7.65830   -4.52296  40.13931  1.000 17.85930  ? 46  ARG L HH12 1 
ATOM   3953 H HH21 . ARG B 2 48  ? 10.23840  -2.66662  39.27430  1.000 28.21118  ? 46  ARG L HH21 1 
ATOM   3954 H HH22 . ARG B 2 48  ? 9.73908   -3.60179  40.32070  1.000 28.21118  ? 46  ARG L HH22 1 
ATOM   3955 N N    . LEU B 2 49  ? 8.33686   1.17133   34.42435  1.000 15.54928  ? 47  LEU L N    1 
ATOM   3956 C CA   . LEU B 2 49  ? 8.71419   2.42118   35.06548  1.000 18.36069  ? 47  LEU L CA   1 
ATOM   3957 C C    . LEU B 2 49  ? 8.14095   2.53725   36.46770  1.000 18.79503  ? 47  LEU L C    1 
ATOM   3958 O O    . LEU B 2 49  ? 8.85236   2.92344   37.39949  1.000 22.33586  ? 47  LEU L O    1 
ATOM   3959 C CB   . LEU B 2 49  ? 8.23126   3.61582   34.23928  1.000 19.80811  ? 47  LEU L CB   1 
ATOM   3960 C CG   . LEU B 2 49  ? 8.58497   3.63780   32.75863  1.000 20.06831  ? 47  LEU L CG   1 
ATOM   3961 C CD1  . LEU B 2 49  ? 7.86202   4.79684   32.09037  1.000 25.49998  ? 47  LEU L CD1  1 
ATOM   3962 C CD2  . LEU B 2 49  ? 10.07232  3.75391   32.56849  1.000 22.29132  ? 47  LEU L CD2  1 
ATOM   3963 H H    . LEU B 2 49  ? 7.53544   1.17727   34.11241  1.000 18.66597  ? 47  LEU L H    1 
ATOM   3964 H HA   . LEU B 2 49  ? 9.68236   2.45628   35.11359  1.000 22.03966  ? 47  LEU L HA   1 
ATOM   3965 H HB2  . LEU B 2 49  ? 7.26337   3.64382   34.29677  1.000 23.77657  ? 47  LEU L HB2  1 
ATOM   3966 H HB3  . LEU B 2 49  ? 8.61017   4.41873   34.63001  1.000 23.77657  ? 47  LEU L HB3  1 
ATOM   3967 H HG   . LEU B 2 49  ? 8.30471   2.80889   32.33997  1.000 24.08880  ? 47  LEU L HG   1 
ATOM   3968 H HD11 . LEU B 2 49  ? 8.23316   4.93188   31.20441  1.000 30.60681  ? 47  LEU L HD11 1 
ATOM   3969 H HD12 . LEU B 2 49  ? 6.91786   4.58436   32.02461  1.000 30.60681  ? 47  LEU L HD12 1 
ATOM   3970 H HD13 . LEU B 2 49  ? 7.98463   5.59635   32.62576  1.000 30.60681  ? 47  LEU L HD13 1 
ATOM   3971 H HD21 . LEU B 2 49  ? 10.26687  3.79771   31.61922  1.000 26.75642  ? 47  LEU L HD21 1 
ATOM   3972 H HD22 . LEU B 2 49  ? 10.38484  4.56032   33.00775  1.000 26.75642  ? 47  LEU L HD22 1 
ATOM   3973 H HD23 . LEU B 2 49  ? 10.50219  2.97686   32.95874  1.000 26.75642  ? 47  LEU L HD23 1 
ATOM   3974 N N    . ILE B 2 50  ? 6.85996   2.21190   36.62833  1.000 17.57395  ? 48  ILE L N    1 
ATOM   3975 C CA   . ILE B 2 50  ? 6.14931   2.43438   37.88593  1.000 19.62612  ? 48  ILE L CA   1 
ATOM   3976 C C    . ILE B 2 50  ? 5.43863   1.14293   38.26417  1.000 18.53089  ? 48  ILE L C    1 
ATOM   3977 O O    . ILE B 2 50  ? 4.89810   0.46509   37.38826  1.000 14.83260  ? 48  ILE L O    1 
ATOM   3978 C CB   . ILE B 2 50  ? 5.11524   3.57812   37.75840  1.000 14.09069  ? 48  ILE L CB   1 
ATOM   3979 C CG1  . ILE B 2 50  ? 5.75656   4.88108   37.25366  1.000 20.44103  ? 48  ILE L CG1  1 
ATOM   3980 C CG2  . ILE B 2 50  ? 4.38505   3.78908   39.06996  1.000 17.07997  ? 48  ILE L CG2  1 
ATOM   3981 C CD1  . ILE B 2 50  ? 6.44720   5.67674   38.30115  1.000 25.20940  ? 48  ILE L CD1  1 
ATOM   3982 H H    . ILE B 2 50  ? 6.37447   1.85583   36.01423  1.000 21.09558  ? 48  ILE L H    1 
ATOM   3983 H HA   . ILE B 2 50  ? 6.78821   2.66384   38.57878  1.000 23.55818  ? 48  ILE L HA   1 
ATOM   3984 H HB   . ILE B 2 50  ? 4.46635   3.30916   37.08945  1.000 16.91566  ? 48  ILE L HB   1 
ATOM   3985 H HG12 . ILE B 2 50  ? 6.41283   4.65920   36.57471  1.000 24.53606  ? 48  ILE L HG12 1 
ATOM   3986 H HG13 . ILE B 2 50  ? 5.06119   5.43996   36.87284  1.000 24.53606  ? 48  ILE L HG13 1 
ATOM   3987 H HG21 . ILE B 2 50  ? 3.90789   4.63281   39.03359  1.000 20.50279  ? 48  ILE L HG21 1 
ATOM   3988 H HG22 . ILE B 2 50  ? 3.75885   3.06042   39.20353  1.000 20.50279  ? 48  ILE L HG22 1 
ATOM   3989 H HG23 . ILE B 2 50  ? 5.03205   3.80584   39.79246  1.000 20.50279  ? 48  ILE L HG23 1 
ATOM   3990 H HD11 . ILE B 2 50  ? 6.99783   6.35125   37.87367  1.000 30.25811  ? 48  ILE L HD11 1 
ATOM   3991 H HD12 . ILE B 2 50  ? 5.78197   6.10147   38.86505  1.000 30.25811  ? 48  ILE L HD12 1 
ATOM   3992 H HD13 . ILE B 2 50  ? 7.00221   5.08486   38.83270  1.000 30.25811  ? 48  ILE L HD13 1 
ATOM   3993 N N    . TYR B 2 51  ? 5.39621   0.82231   39.56110  1.000 14.83932  ? 49  TYR L N    1 
ATOM   3994 C CA   . TYR B 2 51  ? 4.61173   -0.31056  40.04998  1.000 14.31758  ? 49  TYR L CA   1 
ATOM   3995 C C    . TYR B 2 51  ? 3.78714   0.11220   41.26392  1.000 15.60713  ? 49  TYR L C    1 
ATOM   3996 O O    . TYR B 2 51  ? 4.05799   1.12862   41.90532  1.000 14.63185  ? 49  TYR L O    1 
ATOM   3997 C CB   . TYR B 2 51  ? 5.50605   -1.52596  40.37967  1.000 14.27457  ? 49  TYR L CB   1 
ATOM   3998 C CG   . TYR B 2 51  ? 6.35867   -1.39076  41.61932  1.000 16.65917  ? 49  TYR L CG   1 
ATOM   3999 C CD1  . TYR B 2 51  ? 7.60098   -0.77790  41.56699  1.000 24.39930  ? 49  TYR L CD1  1 
ATOM   4000 C CD2  . TYR B 2 51  ? 5.92707   -1.89788  42.83607  1.000 20.52702  ? 49  TYR L CD2  1 
ATOM   4001 C CE1  . TYR B 2 51  ? 8.39001   -0.66180  42.70327  1.000 29.30967  ? 49  TYR L CE1  1 
ATOM   4002 C CE2  . TYR B 2 51  ? 6.70650   -1.78751  43.97658  1.000 28.80895  ? 49  TYR L CE2  1 
ATOM   4003 C CZ   . TYR B 2 51  ? 7.93523   -1.16632  43.90280  1.000 23.61768  ? 49  TYR L CZ   1 
ATOM   4004 O OH   . TYR B 2 51  ? 8.71237   -1.05383  45.03448  1.000 37.32041  ? 49  TYR L OH   1 
ATOM   4005 H H    . TYR B 2 51  ? 5.81624   1.24949   40.17810  1.000 17.81402  ? 49  TYR L H    1 
ATOM   4006 H HA   . TYR B 2 51  ? 3.98605   -0.58891  39.36300  1.000 17.18793  ? 49  TYR L HA   1 
ATOM   4007 H HB2  . TYR B 2 51  ? 4.93465   -2.29960  40.50570  1.000 17.13632  ? 49  TYR L HB2  1 
ATOM   4008 H HB3  . TYR B 2 51  ? 6.10585   -1.67480  39.63202  1.000 17.13632  ? 49  TYR L HB3  1 
ATOM   4009 H HD1  . TYR B 2 51  ? 7.91064   -0.43926  40.75809  1.000 29.28600  ? 49  TYR L HD1  1 
ATOM   4010 H HD2  . TYR B 2 51  ? 5.09974   -2.31953  42.88742  1.000 24.63926  ? 49  TYR L HD2  1 
ATOM   4011 H HE1  . TYR B 2 51  ? 9.22055   -0.24609  42.65550  1.000 35.17843  ? 49  TYR L HE1  1 
ATOM   4012 H HE2  . TYR B 2 51  ? 6.40289   -2.13006  44.78614  1.000 34.57757  ? 49  TYR L HE2  1 
ATOM   4013 H HH   . TYR B 2 51  ? 8.31953   -1.40472  45.68881  1.000 44.79133  ? 49  TYR L HH   1 
ATOM   4014 N N    . ALA B 2 52  ? 2.73425   -0.65549  41.54068  1.000 14.27273  ? 50  ALA L N    1 
ATOM   4015 C CA   . ALA B 2 52  ? 1.82683   -0.39052  42.65815  1.000 18.90795  ? 50  ALA L CA   1 
ATOM   4016 C C    . ALA B 2 52  ? 1.32534   1.05750   42.65334  1.000 19.30649  ? 50  ALA L C    1 
ATOM   4017 O O    . ALA B 2 52  ? 1.33867   1.75111   43.67083  1.000 16.47441  ? 50  ALA L O    1 
ATOM   4018 C CB   . ALA B 2 52  ? 2.50270   -0.73090  43.98831  1.000 19.95700  ? 50  ALA L CB   1 
ATOM   4019 H H    . ALA B 2 52  ? 2.51861   -1.35247  41.08537  1.000 17.13411  ? 50  ALA L H    1 
ATOM   4020 H HA   . ALA B 2 52  ? 1.04741   -0.95821  42.55266  1.000 22.69637  ? 50  ALA L HA   1 
ATOM   4021 H HB1  . ALA B 2 52  ? 1.88224   -0.55309  44.71240  1.000 23.95524  ? 50  ALA L HB1  1 
ATOM   4022 H HB2  . ALA B 2 52  ? 2.74882   -1.66915  43.98649  1.000 23.95524  ? 50  ALA L HB2  1 
ATOM   4023 H HB3  . ALA B 2 52  ? 3.29546   -0.18117  44.08950  1.000 23.95524  ? 50  ALA L HB3  1 
ATOM   4024 N N    . ILE B 2 53  ? 0.87674   1.50746   41.48019  1.000 17.73947  ? 51  ILE L N    1 
ATOM   4025 C CA   . ILE B 2 53  ? 0.33909   2.84618   41.23719  1.000 17.48705  ? 51  ILE L CA   1 
ATOM   4026 C C    . ILE B 2 53  ? 1.42031   3.92072   41.24188  1.000 17.43408  ? 51  ILE L C    1 
ATOM   4027 O O    . ILE B 2 53  ? 1.50183   4.71677   40.30193  1.000 16.60473  ? 51  ILE L O    1 
ATOM   4028 C CB   . ILE B 2 53  ? -0.76112  3.22824   42.24569  1.000 20.10670  ? 51  ILE L CB   1 
ATOM   4029 C CG1  . ILE B 2 53  ? -1.95664  2.28557   42.12068  1.000 24.63952  ? 51  ILE L CG1  1 
ATOM   4030 C CG2  . ILE B 2 53  ? -1.21733  4.66046   41.98357  1.000 20.16986  ? 51  ILE L CG2  1 
ATOM   4031 C CD1  . ILE B 2 53  ? -2.97100  2.42663   43.22092  1.000 28.83366  ? 51  ILE L CD1  1 
ATOM   4032 H H    . ILE B 2 53  ? 0.87310   1.02727   40.76674  1.000 21.29419  ? 51  ILE L H    1 
ATOM   4033 H HA   . ILE B 2 53  ? -0.03362  2.80998   40.34238  1.000 20.99130  ? 51  ILE L HA   1 
ATOM   4034 H HB   . ILE B 2 53  ? -0.39612  3.15387   43.14131  1.000 24.13487  ? 51  ILE L HB   1 
ATOM   4035 H HG12 . ILE B 2 53  ? -2.40700  2.46567   41.28066  1.000 29.57425  ? 51  ILE L HG12 1 
ATOM   4036 H HG13 . ILE B 2 53  ? -1.63324  1.37117   42.13435  1.000 29.57425  ? 51  ILE L HG13 1 
ATOM   4037 H HG21 . ILE B 2 53  ? -2.07918  4.79974   42.40632  1.000 24.21067  ? 51  ILE L HG21 1 
ATOM   4038 H HG22 . ILE B 2 53  ? -0.56367  5.27316   42.35535  1.000 24.21067  ? 51  ILE L HG22 1 
ATOM   4039 H HG23 . ILE B 2 53  ? -1.29242  4.79778   41.02628  1.000 24.21067  ? 51  ILE L HG23 1 
ATOM   4040 H HD11 . ILE B 2 53  ? -3.55082  1.64900   43.21750  1.000 34.60723  ? 51  ILE L HD11 1 
ATOM   4041 H HD12 . ILE B 2 53  ? -2.50811  2.49035   44.07096  1.000 34.60723  ? 51  ILE L HD12 1 
ATOM   4042 H HD13 . ILE B 2 53  ? -3.49343  3.22945   43.06778  1.000 34.60723  ? 51  ILE L HD13 1 
ATOM   4043 N N    . ALA B 2 54  ? 2.24748   3.97663   42.30159  1.000 19.87634  ? 52  ALA L N    1 
ATOM   4044 C CA   . ALA B 2 54  ? 3.09999   5.14423   42.49835  1.000 18.47824  ? 52  ALA L CA   1 
ATOM   4045 C C    . ALA B 2 54  ? 4.53844   4.85282   42.91806  1.000 21.98837  ? 52  ALA L C    1 
ATOM   4046 O O    . ALA B 2 54  ? 5.28168   5.80109   43.19631  1.000 19.26586  ? 52  ALA L O    1 
ATOM   4047 C CB   . ALA B 2 54  ? 2.45966   6.07548   43.54355  1.000 24.50786  ? 52  ALA L CB   1 
ATOM   4048 H H    . ALA B 2 54  ? 2.32568   3.36409   42.90017  1.000 23.85844  ? 52  ALA L H    1 
ATOM   4049 H HA   . ALA B 2 54  ? 3.16605   5.59055   41.63967  1.000 22.18073  ? 52  ALA L HA   1 
ATOM   4050 H HB1  . ALA B 2 54  ? 3.02767   6.85243   43.66440  1.000 29.41627  ? 52  ALA L HB1  1 
ATOM   4051 H HB2  . ALA B 2 54  ? 1.58507   6.35110   43.22729  1.000 29.41627  ? 52  ALA L HB2  1 
ATOM   4052 H HB3  . ALA B 2 54  ? 2.37215   5.59604   44.38223  1.000 29.41627  ? 52  ALA L HB3  1 
ATOM   4053 N N    . SER B 2 55  ? 4.98040   3.60093   42.95352  1.000 20.84488  ? 53  SER L N    1 
ATOM   4054 C CA   . SER B 2 55  ? 6.33622   3.29727   43.40504  1.000 25.36809  ? 53  SER L CA   1 
ATOM   4055 C C    . SER B 2 55  ? 7.30954   3.31709   42.23352  1.000 24.41856  ? 53  SER L C    1 
ATOM   4056 O O    . SER B 2 55  ? 7.07887   2.66541   41.21019  1.000 24.29984  ? 53  SER L O    1 
ATOM   4057 C CB   . SER B 2 55  ? 6.39004   1.94251   44.10898  1.000 24.27974  ? 53  SER L CB   1 
ATOM   4058 O OG   . SER B 2 55  ? 5.63064   1.97369   45.30218  1.000 31.18084  ? 53  SER L OG   1 
ATOM   4059 H H    . SER B 2 55  ? 4.51812   2.91338   42.72291  1.000 25.02069  ? 53  SER L H    1 
ATOM   4060 H HA   . SER B 2 55  ? 6.61057   3.98102   44.03600  1.000 30.44854  ? 53  SER L HA   1 
ATOM   4061 H HB2  . SER B 2 55  ? 6.02610   1.26393   43.51908  1.000 29.14253  ? 53  SER L HB2  1 
ATOM   4062 H HB3  . SER B 2 55  ? 7.31231   1.73398   44.32539  1.000 29.14253  ? 53  SER L HB3  1 
ATOM   4063 H HG   . SER B 2 55  ? 4.82936   2.15600   45.12808  1.000 37.42384  ? 53  SER L HG   1 
ATOM   4064 N N    . LEU B 2 56  ? 8.39741   4.06753   42.39243  1.000 28.78072  ? 54  LEU L N    1 
ATOM   4065 C CA   . LEU B 2 56  ? 9.42653   4.21264   41.37031  1.000 30.04296  ? 54  LEU L CA   1 
ATOM   4066 C C    . LEU B 2 56  ? 10.55145  3.22262   41.65198  1.000 34.55858  ? 54  LEU L C    1 
ATOM   4067 O O    . LEU B 2 56  ? 11.21603  3.30674   42.69009  1.000 41.50392  ? 54  LEU L O    1 
ATOM   4068 C CB   . LEU B 2 56  ? 9.95709   5.64630   41.35343  1.000 37.93866  ? 54  LEU L CB   1 
ATOM   4069 C CG   . LEU B 2 56  ? 10.86042  6.05390   40.19332  1.000 36.51997  ? 54  LEU L CG   1 
ATOM   4070 C CD1  . LEU B 2 56  ? 10.04829  6.29854   38.93283  1.000 31.21115  ? 54  LEU L CD1  1 
ATOM   4071 C CD2  . LEU B 2 56  ? 11.66668  7.29172   40.56435  1.000 36.49294  ? 54  LEU L CD2  1 
ATOM   4072 H H    . LEU B 2 56  ? 8.56536   4.51576   43.10691  1.000 34.54369  ? 54  LEU L H    1 
ATOM   4073 H HA   . LEU B 2 56  ? 9.05639   4.00842   40.49728  1.000 36.05839  ? 54  LEU L HA   1 
ATOM   4074 H HB2  . LEU B 2 56  ? 9.19341   6.24415   41.33704  1.000 45.53322  ? 54  LEU L HB2  1 
ATOM   4075 H HB3  . LEU B 2 56  ? 10.46757  5.78240   42.16694  1.000 45.53322  ? 54  LEU L HB3  1 
ATOM   4076 H HG   . LEU B 2 56  ? 11.47985  5.33121   40.00642  1.000 43.83079  ? 54  LEU L HG   1 
ATOM   4077 H HD11 . LEU B 2 56  ? 10.62916  6.66849   38.24973  1.000 37.46021  ? 54  LEU L HD11 1 
ATOM   4078 H HD12 . LEU B 2 56  ? 9.67518   5.45626   38.62911  1.000 37.46021  ? 54  LEU L HD12 1 
ATOM   4079 H HD13 . LEU B 2 56  ? 9.33409   6.92344   39.13364  1.000 37.46021  ? 54  LEU L HD13 1 
ATOM   4080 H HD21 . LEU B 2 56  ? 12.21150  7.55290   39.80550  1.000 43.79837  ? 54  LEU L HD21 1 
ATOM   4081 H HD22 . LEU B 2 56  ? 11.05584  8.00891   40.79546  1.000 43.79837  ? 54  LEU L HD22 1 
ATOM   4082 H HD23 . LEU B 2 56  ? 12.23421  7.08328   41.32288  1.000 43.79837  ? 54  LEU L HD23 1 
ATOM   4083 N N    . TYR B 2 57  ? 10.75905  2.28588   40.73520  1.000 35.96492  ? 55  TYR L N    1 
ATOM   4084 C CA   . TYR B 2 57  ? 11.79980  1.28806   40.92208  1.000 45.11179  ? 55  TYR L CA   1 
ATOM   4085 C C    . TYR B 2 57  ? 13.18152  1.92574   40.78430  1.000 43.57680  ? 55  TYR L C    1 
ATOM   4086 O O    . TYR B 2 57  ? 13.38838  2.86188   40.00578  1.000 32.29203  ? 55  TYR L O    1 
ATOM   4087 C CB   . TYR B 2 57  ? 11.62482  0.15105   39.91265  1.000 44.64323  ? 55  TYR L CB   1 
ATOM   4088 C CG   . TYR B 2 57  ? 12.60081  -0.98873  40.09482  1.000 47.72101  ? 55  TYR L CG   1 
ATOM   4089 C CD1  . TYR B 2 57  ? 12.64052  -1.71320  41.28008  1.000 50.09422  ? 55  TYR L CD1  1 
ATOM   4090 C CD2  . TYR B 2 57  ? 13.47531  -1.34821  39.07688  1.000 51.88180  ? 55  TYR L CD2  1 
ATOM   4091 C CE1  . TYR B 2 57  ? 13.53329  -2.75937  41.45002  1.000 50.09588  ? 55  TYR L CE1  1 
ATOM   4092 C CE2  . TYR B 2 57  ? 14.36864  -2.39118  39.23575  1.000 56.92250  ? 55  TYR L CE2  1 
ATOM   4093 C CZ   . TYR B 2 57  ? 14.39467  -3.09313  40.42402  1.000 62.48522  ? 55  TYR L CZ   1 
ATOM   4094 O OH   . TYR B 2 57  ? 15.28410  -4.13241  40.58519  1.000 66.75547  ? 55  TYR L OH   1 
ATOM   4095 H H    . TYR B 2 57  ? 10.31460  2.20764   40.00312  1.000 43.16473  ? 55  TYR L H    1 
ATOM   4096 H HA   . TYR B 2 57  ? 11.73820  0.90612   41.81159  1.000 54.14098  ? 55  TYR L HA   1 
ATOM   4097 H HB2  . TYR B 2 57  ? 10.72917  -0.21015  40.00341  1.000 53.57871  ? 55  TYR L HB2  1 
ATOM   4098 H HB3  . TYR B 2 57  ? 11.75011  0.50673   39.01895  1.000 53.57871  ? 55  TYR L HB3  1 
ATOM   4099 H HD1  . TYR B 2 57  ? 12.05823  -1.49225  41.97074  1.000 60.11990  ? 55  TYR L HD1  1 
ATOM   4100 H HD2  . TYR B 2 57  ? 13.45944  -0.87878  38.27420  1.000 62.26499  ? 55  TYR L HD2  1 
ATOM   4101 H HE1  . TYR B 2 57  ? 13.55205  -3.23348  42.24987  1.000 60.12190  ? 55  TYR L HE1  1 
ATOM   4102 H HE2  . TYR B 2 57  ? 14.94905  -2.61871  38.54564  1.000 68.31384  ? 55  TYR L HE2  1 
ATOM   4103 H HH   . TYR B 2 57  ? 15.74684  -4.22492  39.89027  1.000 80.11340  ? 55  TYR L HH   1 
ATOM   4104 N N    . SER B 2 58  ? 14.13045  1.41312   41.56690  1.000 43.01486  ? 56  SER L N    1 
ATOM   4105 C CA   . SER B 2 58  ? 15.49232  1.93116   41.53909  1.000 42.75181  ? 56  SER L CA   1 
ATOM   4106 C C    . SER B 2 58  ? 16.04236  1.92553   40.11846  1.000 36.30476  ? 56  SER L C    1 
ATOM   4107 O O    . SER B 2 58  ? 15.87151  0.96026   39.36947  1.000 39.65464  ? 56  SER L O    1 
ATOM   4108 C CB   . SER B 2 58  ? 16.39104  1.10093   42.46021  1.000 48.24083  ? 56  SER L CB   1 
ATOM   4109 O OG   . SER B 2 58  ? 16.25471  1.51830   43.80941  1.000 53.80875  ? 56  SER L OG   1 
ATOM   4110 H H    . SER B 2 58  ? 14.00991  0.76648   42.12091  1.000 51.62466  ? 56  SER L H    1 
ATOM   4111 H HA   . SER B 2 58  ? 15.49390  2.84662   41.85977  1.000 51.30901  ? 56  SER L HA   1 
ATOM   4112 H HB2  . SER B 2 58  ? 16.13707  0.16730   42.39137  1.000 57.89583  ? 56  SER L HB2  1 
ATOM   4113 H HB3  . SER B 2 58  ? 17.31462  1.21456   42.18639  1.000 57.89583  ? 56  SER L HB3  1 
ATOM   4114 H HG   . SER B 2 58  ? 16.79860  1.10164   44.29539  1.000 64.57733  ? 56  SER L HG   1 
ATOM   4115 N N    . GLY B 2 59  ? 16.69532  3.02578   39.74671  1.000 29.47952  ? 57  GLY L N    1 
ATOM   4116 C CA   . GLY B 2 59  ? 17.25109  3.18745   38.42561  1.000 32.51678  ? 57  GLY L CA   1 
ATOM   4117 C C    . GLY B 2 59  ? 16.33857  3.87739   37.43403  1.000 33.54291  ? 57  GLY L C    1 
ATOM   4118 O O    . GLY B 2 59  ? 16.81755  4.35796   36.39834  1.000 34.39249  ? 57  GLY L O    1 
ATOM   4119 H H    . GLY B 2 59  ? 16.82712  3.70235   40.26099  1.000 35.38226  ? 57  GLY L H    1 
ATOM   4120 H HA2  . GLY B 2 59  ? 18.06525  3.71048   38.49257  1.000 39.02698  ? 57  GLY L HA2  1 
ATOM   4121 H HA3  . GLY B 2 59  ? 17.46695  2.31133   38.06964  1.000 39.02698  ? 57  GLY L HA3  1 
ATOM   4122 N N    . VAL B 2 60  ? 15.04651  3.94890   37.71902  1.000 30.33437  ? 58  VAL L N    1 
ATOM   4123 C CA   . VAL B 2 60  ? 14.11715  4.63493   36.81874  1.000 23.10833  ? 58  VAL L CA   1 
ATOM   4124 C C    . VAL B 2 60  ? 14.25595  6.13763   37.03071  1.000 22.24069  ? 58  VAL L C    1 
ATOM   4125 O O    . VAL B 2 60  ? 14.26226  6.59358   38.18346  1.000 20.82883  ? 58  VAL L O    1 
ATOM   4126 C CB   . VAL B 2 60  ? 12.68624  4.17198   37.06904  1.000 23.86349  ? 58  VAL L CB   1 
ATOM   4127 C CG1  . VAL B 2 60  ? 11.72119  4.92417   36.15305  1.000 21.15002  ? 58  VAL L CG1  1 
ATOM   4128 C CG2  . VAL B 2 60  ? 12.56736  2.66152   36.85761  1.000 26.75684  ? 58  VAL L CG2  1 
ATOM   4129 H H    . VAL B 2 60  ? 14.68048  3.61258   38.42081  1.000 36.40807  ? 58  VAL L H    1 
ATOM   4130 H HA   . VAL B 2 60  ? 14.34554  4.42899   35.89878  1.000 27.73683  ? 58  VAL L HA   1 
ATOM   4131 H HB   . VAL B 2 60  ? 12.44598  4.36504   37.98877  1.000 28.64303  ? 58  VAL L HB   1 
ATOM   4132 H HG11 . VAL B 2 60  ? 10.84522  4.51147   36.21007  1.000 25.38685  ? 58  VAL L HG11 1 
ATOM   4133 H HG12 . VAL B 2 60  ? 11.67019  5.84946   36.43965  1.000 25.38685  ? 58  VAL L HG12 1 
ATOM   4134 H HG13 . VAL B 2 60  ? 12.04998  4.87784   35.24165  1.000 25.38685  ? 58  VAL L HG13 1 
ATOM   4135 H HG21 . VAL B 2 60  ? 11.63947  2.39976   36.96442  1.000 32.11504  ? 58  VAL L HG21 1 
ATOM   4136 H HG22 . VAL B 2 60  ? 12.87182  2.44294   35.96294  1.000 32.11504  ? 58  VAL L HG22 1 
ATOM   4137 H HG23 . VAL B 2 60  ? 13.11715  2.20645   37.51452  1.000 32.11504  ? 58  VAL L HG23 1 
ATOM   4138 N N    . PRO B 2 61  ? 14.37671  6.93204   35.96854  1.000 20.96372  ? 59  PRO L N    1 
ATOM   4139 C CA   . PRO B 2 61  ? 14.56867  8.37438   36.15166  1.000 20.69867  ? 59  PRO L CA   1 
ATOM   4140 C C    . PRO B 2 61  ? 13.44812  9.00440   36.96425  1.000 21.78908  ? 59  PRO L C    1 
ATOM   4141 O O    . PRO B 2 61  ? 12.27712  8.63029   36.85117  1.000 18.47526  ? 59  PRO L O    1 
ATOM   4142 C CB   . PRO B 2 61  ? 14.59410  8.91212   34.71704  1.000 19.66226  ? 59  PRO L CB   1 
ATOM   4143 C CG   . PRO B 2 61  ? 15.04867  7.76267   33.89913  1.000 22.82657  ? 59  PRO L CG   1 
ATOM   4144 C CD   . PRO B 2 61  ? 14.50005  6.53497   34.55454  1.000 23.91200  ? 59  PRO L CD   1 
ATOM   4145 H HA   . PRO B 2 61  ? 15.41684  8.54754   36.58929  1.000 24.84524  ? 59  PRO L HA   1 
ATOM   4146 H HB2  . PRO B 2 61  ? 13.70552  9.19836   34.45360  1.000 23.60155  ? 59  PRO L HB2  1 
ATOM   4147 H HB3  . PRO B 2 61  ? 15.21489  9.65455   34.65135  1.000 23.60155  ? 59  PRO L HB3  1 
ATOM   4148 H HG2  . PRO B 2 61  ? 14.70520  7.85031   32.99622  1.000 27.39872  ? 59  PRO L HG2  1 
ATOM   4149 H HG3  . PRO B 2 61  ? 16.01823  7.73765   33.88429  1.000 27.39872  ? 59  PRO L HG3  1 
ATOM   4150 H HD2  . PRO B 2 61  ? 13.63394  6.30360   34.18411  1.000 28.70124  ? 59  PRO L HD2  1 
ATOM   4151 H HD3  . PRO B 2 61  ? 15.11237  5.78894   34.45760  1.000 28.70124  ? 59  PRO L HD3  1 
ATOM   4152 N N    . SER B 2 62  ? 13.82436  9.99173   37.77628  1.000 19.57818  ? 60  SER L N    1 
ATOM   4153 C CA   . SER B 2 62  ? 12.88722  10.63285  38.68453  1.000 19.60452  ? 60  SER L CA   1 
ATOM   4154 C C    . SER B 2 62  ? 11.83485  11.46905  37.96682  1.000 19.87006  ? 60  SER L C    1 
ATOM   4155 O O    . SER B 2 62  ? 10.84396  11.84641  38.59831  1.000 17.86006  ? 60  SER L O    1 
ATOM   4156 C CB   . SER B 2 62  ? 13.65460  11.50878  39.67457  1.000 24.20965  ? 60  SER L CB   1 
ATOM   4157 O OG   . SER B 2 62  ? 14.40786  12.49401  38.99109  1.000 21.55002  ? 60  SER L OG   1 
ATOM   4158 H H    . SER B 2 62  ? 14.62292  10.30821  37.81795  1.000 23.50065  ? 60  SER L H    1 
ATOM   4159 H HA   . SER B 2 62  ? 12.41863  9.94521   39.18300  1.000 23.53225  ? 60  SER L HA   1 
ATOM   4160 H HB2  . SER B 2 62  ? 13.02233  11.94720  40.26526  1.000 29.05842  ? 60  SER L HB2  1 
ATOM   4161 H HB3  . SER B 2 62  ? 14.25764  10.95034  40.18973  1.000 29.05842  ? 60  SER L HB3  1 
ATOM   4162 H HG   . SER B 2 62  ? 13.89429  13.00305  38.56364  1.000 25.86686  ? 60  SER L HG   1 
ATOM   4163 N N    . ARG B 2 63  ? 12.01704  11.77235  36.67806  1.000 17.39359  ? 61  ARG L N    1 
ATOM   4164 C CA   . ARG B 2 63  ? 11.02023  12.56100  35.96035  1.000 22.34267  ? 61  ARG L CA   1 
ATOM   4165 C C    . ARG B 2 63  ? 9.71419   11.80246  35.76078  1.000 15.30866  ? 61  ARG L C    1 
ATOM   4166 O O    . ARG B 2 63  ? 8.69729   12.42294  35.43456  1.000 18.54637  ? 61  ARG L O    1 
ATOM   4167 C CB   . ARG B 2 63  ? 11.56474  13.00971  34.60490  1.000 17.45947  ? 61  ARG L CB   1 
ATOM   4168 C CG   . ARG B 2 63  ? 12.00357  11.88157  33.67968  1.000 19.49092  ? 61  ARG L CG   1 
ATOM   4169 C CD   . ARG B 2 63  ? 12.49306  12.45047  32.34425  1.000 16.70423  ? 61  ARG L CD   1 
ATOM   4170 N NE   . ARG B 2 63  ? 12.93112  11.40746  31.42663  1.000 17.96109  ? 61  ARG L NE   1 
ATOM   4171 C CZ   . ARG B 2 63  ? 14.14959  10.88506  31.40913  1.000 18.26133  ? 61  ARG L CZ   1 
ATOM   4172 N NH1  . ARG B 2 63  ? 15.08475  11.28303  32.25619  1.000 22.22446  ? 61  ARG L NH1  1 
ATOM   4173 N NH2  . ARG B 2 63  ? 14.43228  9.93111   30.53011  1.000 19.44934  ? 61  ARG L NH2  1 
ATOM   4174 H H    . ARG B 2 63  ? 12.69726  11.53679  36.20752  1.000 20.87915  ? 61  ARG L H    1 
ATOM   4175 H HA   . ARG B 2 63  ? 10.83131  13.35636  36.48247  1.000 26.81804  ? 61  ARG L HA   1 
ATOM   4176 H HB2  . ARG B 2 63  ? 10.87117  13.50877  34.14578  1.000 20.95820  ? 61  ARG L HB2  1 
ATOM   4177 H HB3  . ARG B 2 63  ? 12.33643  13.57736  34.75711  1.000 20.95820  ? 61  ARG L HB3  1 
ATOM   4178 H HG2  . ARG B 2 63  ? 12.72963  11.38673  34.09062  1.000 23.39594  ? 61  ARG L HG2  1 
ATOM   4179 H HG3  . ARG B 2 63  ? 11.25406  11.29009  33.50860  1.000 23.39594  ? 61  ARG L HG3  1 
ATOM   4180 H HD2  . ARG B 2 63  ? 11.76916  12.93910  31.92222  1.000 20.05191  ? 61  ARG L HD2  1 
ATOM   4181 H HD3  . ARG B 2 63  ? 13.24310  13.04365  32.50701  1.000 20.05191  ? 61  ARG L HD3  1 
ATOM   4182 H HE   . ARG B 2 63  ? 12.35986  11.10992  30.85678  1.000 21.56014  ? 61  ARG L HE   1 
ATOM   4183 H HH11 . ARG B 2 63  ? 14.90856  11.89390  32.83532  1.000 26.67618  ? 61  ARG L HH11 1 
ATOM   4184 H HH12 . ARG B 2 63  ? 15.86881  10.93085  32.22766  1.000 26.67618  ? 61  ARG L HH12 1 
ATOM   4185 H HH21 . ARG B 2 63  ? 13.82845  9.65942   29.98132  1.000 23.34604  ? 61  ARG L HH21 1 
ATOM   4186 H HH22 . ARG B 2 63  ? 15.21923  9.58486   30.50950  1.000 23.34604  ? 61  ARG L HH22 1 
ATOM   4187 N N    . PHE B 2 64  ? 9.71883   10.48724  35.95075  1.000 13.58826  ? 62  PHE L N    1 
ATOM   4188 C CA   . PHE B 2 64  ? 8.50714   9.67984   35.89052  1.000 17.92491  ? 62  PHE L CA   1 
ATOM   4189 C C    . PHE B 2 64  ? 7.87870   9.57368   37.27425  1.000 16.12451  ? 62  PHE L C    1 
ATOM   4190 O O    . PHE B 2 64  ? 8.56849   9.26902   38.25343  1.000 17.32692  ? 62  PHE L O    1 
ATOM   4191 C CB   . PHE B 2 64  ? 8.81850   8.27727   35.36332  1.000 15.83152  ? 62  PHE L CB   1 
ATOM   4192 C CG   . PHE B 2 64  ? 9.36145   8.25767   33.96463  1.000 15.99748  ? 62  PHE L CG   1 
ATOM   4193 C CD1  . PHE B 2 64  ? 8.51229   8.35648   32.88090  1.000 14.77742  ? 62  PHE L CD1  1 
ATOM   4194 C CD2  . PHE B 2 64  ? 10.72067  8.12236   33.73335  1.000 18.82548  ? 62  PHE L CD2  1 
ATOM   4195 C CE1  . PHE B 2 64  ? 9.00610   8.33074   31.59221  1.000 16.97410  ? 62  PHE L CE1  1 
ATOM   4196 C CE2  . PHE B 2 64  ? 11.21787  8.08910   32.44618  1.000 17.38378  ? 62  PHE L CE2  1 
ATOM   4197 C CZ   . PHE B 2 64  ? 10.36061  8.20311   31.37643  1.000 18.48169  ? 62  PHE L CZ   1 
ATOM   4198 H H    . PHE B 2 64  ? 10.42723  10.02984  36.11973  1.000 16.31275  ? 62  PHE L H    1 
ATOM   4199 H HA   . PHE B 2 64  ? 7.87425   10.10734  35.29252  1.000 21.51673  ? 62  PHE L HA   1 
ATOM   4200 H HB2  . PHE B 2 64  ? 9.47993   7.86718   35.94232  1.000 19.00466  ? 62  PHE L HB2  1 
ATOM   4201 H HB3  . PHE B 2 64  ? 8.00170   7.75411   35.37008  1.000 19.00466  ? 62  PHE L HB3  1 
ATOM   4202 H HD1  . PHE B 2 64  ? 7.59678   8.44139   33.02063  1.000 17.73974  ? 62  PHE L HD1  1 
ATOM   4203 H HD2  . PHE B 2 64  ? 11.30483  8.05315   34.45367  1.000 22.59741  ? 62  PHE L HD2  1 
ATOM   4204 H HE1  . PHE B 2 64  ? 8.42449   8.39955   30.86979  1.000 20.37576  ? 62  PHE L HE1  1 
ATOM   4205 H HE2  . PHE B 2 64  ? 12.13129  7.98973   32.30232  1.000 20.86738  ? 62  PHE L HE2  1 
ATOM   4206 H HZ   . PHE B 2 64  ? 10.69506  8.19404   30.50870  1.000 22.18486  ? 62  PHE L HZ   1 
ATOM   4207 N N    . SER B 2 65  ? 6.57341   9.82151   37.35390  1.000 18.15015  ? 63  SER L N    1 
ATOM   4208 C CA   . SER B 2 65  ? 5.82794   9.57223   38.57995  1.000 16.61964  ? 63  SER L CA   1 
ATOM   4209 C C    . SER B 2 65  ? 4.45333   9.02130   38.22879  1.000 16.82900  ? 63  SER L C    1 
ATOM   4210 O O    . SER B 2 65  ? 3.89794   9.31313   37.16627  1.000 18.53037  ? 63  SER L O    1 
ATOM   4211 C CB   . SER B 2 65  ? 5.67585   10.83357  39.43781  1.000 21.76339  ? 63  SER L CB   1 
ATOM   4212 O OG   . SER B 2 65  ? 4.86668   11.79394  38.79540  1.000 27.85403  ? 63  SER L OG   1 
ATOM   4213 H H    . SER B 2 65  ? 6.09846   10.13478  36.70901  1.000 21.78701  ? 63  SER L H    1 
ATOM   4214 H HA   . SER B 2 65  ? 6.30214   8.91038   39.10720  1.000 19.95040  ? 63  SER L HA   1 
ATOM   4215 H HB2  . SER B 2 65  ? 5.26534   10.59134  40.28262  1.000 26.12291  ? 63  SER L HB2  1 
ATOM   4216 H HB3  . SER B 2 65  ? 6.55380   11.21568  39.59306  1.000 26.12291  ? 63  SER L HB3  1 
ATOM   4217 H HG   . SER B 2 65  ? 5.21728   12.02458  38.06774  1.000 33.43167  ? 63  SER L HG   1 
ATOM   4218 N N    . GLY B 2 66  ? 3.91525   8.21365   39.13312  1.000 16.02741  ? 64  GLY L N    1 
ATOM   4219 C CA   . GLY B 2 66  ? 2.59839   7.63717   38.96487  1.000 13.24093  ? 64  GLY L CA   1 
ATOM   4220 C C    . GLY B 2 66  ? 1.70898   8.03269   40.12586  1.000 17.05428  ? 64  GLY L C    1 
ATOM   4221 O O    . GLY B 2 66  ? 2.18350   8.27484   41.23531  1.000 16.15815  ? 64  GLY L O    1 
ATOM   4222 H H    . GLY B 2 66  ? 4.30382   7.98279   39.86478  1.000 19.23973  ? 64  GLY L H    1 
ATOM   4223 H HA2  . GLY B 2 66  ? 2.20062   7.95594   38.13960  1.000 15.89596  ? 64  GLY L HA2  1 
ATOM   4224 H HA3  . GLY B 2 66  ? 2.66245   6.66986   38.93154  1.000 15.89596  ? 64  GLY L HA3  1 
ATOM   4225 N N    . SER B 2 67  ? 0.41207   8.12003   39.85563  1.000 12.27045  ? 65  SER L N    1 
ATOM   4226 C CA   . SER B 2 67  ? -0.54553  8.44285   40.90049  1.000 15.83361  ? 65  SER L CA   1 
ATOM   4227 C C    . SER B 2 67  ? -1.89656  7.87261   40.50693  1.000 18.08197  ? 65  SER L C    1 
ATOM   4228 O O    . SER B 2 67  ? -2.07017  7.34523   39.40635  1.000 15.09210  ? 65  SER L O    1 
ATOM   4229 C CB   . SER B 2 67  ? -0.63725  9.95625   41.13478  1.000 21.29421  ? 65  SER L CB   1 
ATOM   4230 O OG   . SER B 2 67  ? -1.14319  10.62301  39.99058  1.000 23.66459  ? 65  SER L OG   1 
ATOM   4231 H H    . SER B 2 67  ? 0.06526   7.99701   39.07833  1.000 14.73137  ? 65  SER L H    1 
ATOM   4232 H HA   . SER B 2 67  ? -0.26502  8.02764   41.73104  1.000 19.00717  ? 65  SER L HA   1 
ATOM   4233 H HB2  . SER B 2 67  ? -1.23081  10.12289  41.88366  1.000 25.55988  ? 65  SER L HB2  1 
ATOM   4234 H HB3  . SER B 2 67  ? 0.24897   10.29806  41.33142  1.000 25.55988  ? 65  SER L HB3  1 
ATOM   4235 H HG   . SER B 2 67  ? -0.63446  10.49429  39.33466  1.000 28.40434  ? 65  SER L HG   1 
ATOM   4236 N N    . GLY B 2 68  ? -2.86140  7.98945   41.41128  1.000 21.07987  ? 66  GLY L N    1 
ATOM   4237 C CA   . GLY B 2 68  ? -4.20688  7.56270   41.11948  1.000 20.68830  ? 66  GLY L CA   1 
ATOM   4238 C C    . GLY B 2 68  ? -4.73746  6.60996   42.16187  1.000 23.89874  ? 66  GLY L C    1 
ATOM   4239 O O    . GLY B 2 68  ? -4.10706  6.34313   43.18950  1.000 18.58207  ? 66  GLY L O    1 
ATOM   4240 H H    . GLY B 2 68  ? -2.75164  8.31465   42.19982  1.000 25.30268  ? 66  GLY L H    1 
ATOM   4241 H HA2  . GLY B 2 68  ? -4.79081  8.33651   41.08572  1.000 24.83280  ? 66  GLY L HA2  1 
ATOM   4242 H HA3  . GLY B 2 68  ? -4.22434  7.11609   40.25859  1.000 24.83280  ? 66  GLY L HA3  1 
ATOM   4243 N N    . SER B 2 69  ? -5.91944  6.07702   41.89515  1.000 22.31804  ? 67  SER L N    1 
ATOM   4244 C CA   . SER B 2 69  ? -6.59649  5.27359   42.90571  1.000 34.94244  ? 67  SER L CA   1 
ATOM   4245 C C    . SER B 2 69  ? -7.52890  4.28251   42.23480  1.000 40.86667  ? 67  SER L C    1 
ATOM   4246 O O    . SER B 2 69  ? -8.37259  4.67580   41.41605  1.000 40.73815  ? 67  SER L O    1 
ATOM   4247 C CB   . SER B 2 69  ? -7.36984  6.16572   43.87998  1.000 46.89234  ? 67  SER L CB   1 
ATOM   4248 O OG   . SER B 2 69  ? -7.93143  5.39816   44.93350  1.000 72.00477  ? 67  SER L OG   1 
ATOM   4249 H H    . SER B 2 69  ? -6.34353  6.16308   41.15195  1.000 26.78848  ? 67  SER L H    1 
ATOM   4250 H HA   . SER B 2 69  ? -5.93288  4.76508   43.39760  1.000 41.93777  ? 67  SER L HA   1 
ATOM   4251 H HB2  . SER B 2 69  ? -6.76277  6.82184   44.25666  1.000 56.27764  ? 67  SER L HB2  1 
ATOM   4252 H HB3  . SER B 2 69  ? -8.08441  6.61227   43.39947  1.000 56.27764  ? 67  SER L HB3  1 
ATOM   4253 H HG   . SER B 2 69  ? -8.24991  5.90673   45.52131  1.000 86.41256  ? 67  SER L HG   1 
ATOM   4254 N N    . GLY B 2 70  ? -7.33344  3.00190   42.56868  1.000 37.30661  ? 68  GLY L N    1 
ATOM   4255 C CA   . GLY B 2 70  ? -8.24014  1.91518   42.25012  1.000 37.98229  ? 68  GLY L CA   1 
ATOM   4256 C C    . GLY B 2 70  ? -8.60079  1.73529   40.79035  1.000 33.51862  ? 68  GLY L C    1 
ATOM   4257 O O    . GLY B 2 70  ? -8.38825  0.65941   40.21852  1.000 30.39527  ? 68  GLY L O    1 
ATOM   4258 H H    . GLY B 2 70  ? -6.64324  2.72980   43.00364  1.000 44.77477  ? 68  GLY L H    1 
ATOM   4259 H HA2  . GLY B 2 70  ? -7.83745  1.08550   42.55074  1.000 45.58559  ? 68  GLY L HA2  1 
ATOM   4260 H HA3  . GLY B 2 70  ? -9.06803  2.05823   42.73491  1.000 45.58559  ? 68  GLY L HA3  1 
ATOM   4261 N N    . THR B 2 71  ? -9.17343  2.77785   40.18699  1.000 26.91773  ? 69  THR L N    1 
ATOM   4262 C CA   . THR B 2 71  ? -9.69653  2.70492   38.83217  1.000 28.29936  ? 69  THR L CA   1 
ATOM   4263 C C    . THR B 2 71  ? -9.19528  3.80205   37.90100  1.000 25.81314  ? 69  THR L C    1 
ATOM   4264 O O    . THR B 2 71  ? -9.44935  3.70956   36.69505  1.000 23.12042  ? 69  THR L O    1 
ATOM   4265 C CB   . THR B 2 71  ? -11.22984 2.76047   38.86271  1.000 32.97124  ? 69  THR L CB   1 
ATOM   4266 O OG1  . THR B 2 71  ? -11.63667 3.87896   39.66112  1.000 38.89711  ? 69  THR L OG1  1 
ATOM   4267 C CG2  . THR B 2 71  ? -11.80443 1.47144   39.45669  1.000 34.97521  ? 69  THR L CG2  1 
ATOM   4268 H H    . THR B 2 71  ? -9.27045  3.55051   40.55192  1.000 32.30812  ? 69  THR L H    1 
ATOM   4269 H HA   . THR B 2 71  ? -9.42527  1.85692   38.44718  1.000 33.96607  ? 69  THR L HA   1 
ATOM   4270 H HB   . THR B 2 71  ? -11.57617 2.85505   37.96159  1.000 39.57232  ? 69  THR L HB   1 
ATOM   4271 H HG1  . THR B 2 71  ? -11.26632 4.57995   39.38352  1.000 46.68336  ? 69  THR L HG1  1 
ATOM   4272 H HG21 . THR B 2 71  ? -12.77137 1.53095   39.50570  1.000 41.97709  ? 69  THR L HG21 1 
ATOM   4273 H HG22 . THR B 2 71  ? -11.56343 0.71383   38.90095  1.000 41.97709  ? 69  THR L HG22 1 
ATOM   4274 H HG23 . THR B 2 71  ? -11.45199 1.33167   40.34952  1.000 41.97709  ? 69  THR L HG23 1 
ATOM   4275 N N    . ASP B 2 72  ? -8.50162  4.82683   38.40169  1.000 22.37759  ? 70  ASP L N    1 
ATOM   4276 C CA   . ASP B 2 72  ? -8.05419  5.93549   37.55877  1.000 21.10292  ? 70  ASP L CA   1 
ATOM   4277 C C    . ASP B 2 72  ? -6.60622  6.25265   37.88738  1.000 20.42840  ? 70  ASP L C    1 
ATOM   4278 O O    . ASP B 2 72  ? -6.28553  6.58123   39.03024  1.000 19.39339  ? 70  ASP L O    1 
ATOM   4279 C CB   . ASP B 2 72  ? -8.94635  7.15997   37.75384  1.000 23.60517  ? 70  ASP L CB   1 
ATOM   4280 C CG   . ASP B 2 72  ? -10.38441 6.87925   37.37852  1.000 33.50664  ? 70  ASP L CG   1 
ATOM   4281 O OD1  . ASP B 2 72  ? -10.72368 6.99634   36.18081  1.000 29.67798  ? 70  ASP L OD1  1 
ATOM   4282 O OD2  . ASP B 2 72  ? -11.16300 6.49801   38.27921  1.000 39.22059  ? 70  ASP L OD2  1 
ATOM   4283 H H    . ASP B 2 72  ? -8.27815  4.90132   39.22880  1.000 26.85995  ? 70  ASP L H    1 
ATOM   4284 H HA   . ASP B 2 72  ? -8.09385  5.67484   36.62528  1.000 25.33034  ? 70  ASP L HA   1 
ATOM   4285 H HB2  . ASP B 2 72  ? -8.92293  7.42638   38.68624  1.000 28.33304  ? 70  ASP L HB2  1 
ATOM   4286 H HB3  . ASP B 2 72  ? -8.62259  7.88293   37.19400  1.000 28.33304  ? 70  ASP L HB3  1 
ATOM   4287 N N    . PHE B 2 73  ? -5.73511  6.14105   36.88811  1.000 15.54571  ? 71  PHE L N    1 
ATOM   4288 C CA   . PHE B 2 73  ? -4.29753  6.17858   37.09442  1.000 15.36044  ? 71  PHE L CA   1 
ATOM   4289 C C    . PHE B 2 73  ? -3.68084  7.20758   36.16656  1.000 17.17280  ? 71  PHE L C    1 
ATOM   4290 O O    . PHE B 2 73  ? -4.18531  7.46296   35.07481  1.000 15.22265  ? 71  PHE L O    1 
ATOM   4291 C CB   . PHE B 2 73  ? -3.70151  4.78989   36.86132  1.000 21.97600  ? 71  PHE L CB   1 
ATOM   4292 C CG   . PHE B 2 73  ? -4.50600  3.70048   37.49539  1.000 20.38857  ? 71  PHE L CG   1 
ATOM   4293 C CD1  . PHE B 2 73  ? -4.50627  3.53996   38.86701  1.000 26.43567  ? 71  PHE L CD1  1 
ATOM   4294 C CD2  . PHE B 2 73  ? -5.29683  2.86605   36.72447  1.000 30.74129  ? 71  PHE L CD2  1 
ATOM   4295 C CE1  . PHE B 2 73  ? -5.26385  2.54900   39.46413  1.000 31.96742  ? 71  PHE L CE1  1 
ATOM   4296 C CE2  . PHE B 2 73  ? -6.05480  1.87465   37.31648  1.000 27.36067  ? 71  PHE L CE2  1 
ATOM   4297 C CZ   . PHE B 2 73  ? -6.03985  1.72314   38.68659  1.000 21.24242  ? 71  PHE L CZ   1 
ATOM   4298 H H    . PHE B 2 73  ? -5.96138  6.04061   36.06451  1.000 18.66168  ? 71  PHE L H    1 
ATOM   4299 H HA   . PHE B 2 73  ? -4.07978  6.45344   37.99881  1.000 18.43937  ? 71  PHE L HA   1 
ATOM   4300 H HB2  . PHE B 2 73  ? -3.66371  4.61872   35.90729  1.000 26.37804  ? 71  PHE L HB2  1 
ATOM   4301 H HB3  . PHE B 2 73  ? -2.80848  4.76225   37.23898  1.000 26.37804  ? 71  PHE L HB3  1 
ATOM   4302 H HD1  . PHE B 2 73  ? -3.99064  4.10524   39.39567  1.000 31.72964  ? 71  PHE L HD1  1 
ATOM   4303 H HD2  . PHE B 2 73  ? -5.31799  2.97375   35.80097  1.000 36.89638  ? 71  PHE L HD2  1 
ATOM   4304 H HE1  . PHE B 2 73  ? -5.24827  2.44192   40.38781  1.000 38.36774  ? 71  PHE L HE1  1 
ATOM   4305 H HE2  . PHE B 2 73  ? -6.57466  1.30997   36.79134  1.000 32.83963  ? 71  PHE L HE2  1 
ATOM   4306 H HZ   . PHE B 2 73  ? -6.55610  1.06049   39.08570  1.000 25.49774  ? 71  PHE L HZ   1 
ATOM   4307 N N    . THR B 2 74  ? -2.59088  7.80743   36.61942  1.000 16.38280  ? 72  THR L N    1 
ATOM   4308 C CA   . THR B 2 74  ? -1.94203  8.88370   35.89425  1.000 13.15981  ? 72  THR L CA   1 
ATOM   4309 C C    . THR B 2 74  ? -0.44779  8.63224   35.87602  1.000 14.68612  ? 72  THR L C    1 
ATOM   4310 O O    . THR B 2 74  ? 0.15124   8.34754   36.91934  1.000 17.88474  ? 72  THR L O    1 
ATOM   4311 C CB   . THR B 2 74  ? -2.24420  10.24215  36.53451  1.000 20.51445  ? 72  THR L CB   1 
ATOM   4312 O OG1  . THR B 2 74  ? -3.66228  10.42385  36.62413  1.000 22.33737  ? 72  THR L OG1  1 
ATOM   4313 C CG2  . THR B 2 74  ? -1.65255  11.36531  35.69932  1.000 22.72779  ? 72  THR L CG2  1 
ATOM   4314 H H    . THR B 2 74  ? -2.20205  7.60359   37.35892  1.000 19.66619  ? 72  THR L H    1 
ATOM   4315 H HA   . THR B 2 74  ? -2.26186  8.90112   34.97866  1.000 15.79861  ? 72  THR L HA   1 
ATOM   4316 H HB   . THR B 2 74  ? -1.85349  10.27613  37.42169  1.000 24.62417  ? 72  THR L HB   1 
ATOM   4317 H HG1  . THR B 2 74  ? -4.00192  10.41702  35.85589  1.000 26.81167  ? 72  THR L HG1  1 
ATOM   4318 H HG21 . THR B 2 74  ? -1.95056  12.22366  36.03891  1.000 27.28018  ? 72  THR L HG21 1 
ATOM   4319 H HG22 . THR B 2 74  ? -0.68385  11.33129  35.73620  1.000 27.28018  ? 72  THR L HG22 1 
ATOM   4320 H HG23 . THR B 2 74  ? -1.93573  11.27660  34.77583  1.000 27.28018  ? 72  THR L HG23 1 
ATOM   4321 N N    . LEU B 2 75  ? 0.13992   8.71216   34.68939  1.000 13.72037  ? 73  LEU L N    1 
ATOM   4322 C CA   . LEU B 2 75  ? 1.58037   8.80799   34.53461  1.000 13.80222  ? 73  LEU L CA   1 
ATOM   4323 C C    . LEU B 2 75  ? 1.92898   10.24710  34.17681  1.000 15.05504  ? 73  LEU L C    1 
ATOM   4324 O O    . LEU B 2 75  ? 1.36444   10.81376  33.23374  1.000 13.19908  ? 73  LEU L O    1 
ATOM   4325 C CB   . LEU B 2 75  ? 2.08875   7.85913   33.45496  1.000 12.84845  ? 73  LEU L CB   1 
ATOM   4326 C CG   . LEU B 2 75  ? 3.60329   7.86328   33.24269  1.000 13.03214  ? 73  LEU L CG   1 
ATOM   4327 C CD1  . LEU B 2 75  ? 4.33217   7.21891   34.41594  1.000 17.03596  ? 73  LEU L CD1  1 
ATOM   4328 C CD2  . LEU B 2 75  ? 3.92984   7.16066   31.94346  1.000 18.05348  ? 73  LEU L CD2  1 
ATOM   4329 H H    . LEU B 2 75  ? -0.28682  8.71257   33.94273  1.000 16.47127  ? 73  LEU L H    1 
ATOM   4330 H HA   . LEU B 2 75  ? 2.01848   8.56630   35.36560  1.000 16.56950  ? 73  LEU L HA   1 
ATOM   4331 H HB2  . LEU B 2 75  ? 1.83197   6.95561   33.69704  1.000 15.42498  ? 73  LEU L HB2  1 
ATOM   4332 H HB3  . LEU B 2 75  ? 1.67679   8.10663   32.61238  1.000 15.42498  ? 73  LEU L HB3  1 
ATOM   4333 H HG   . LEU B 2 75  ? 3.91850   8.77913   33.19009  1.000 15.64541  ? 73  LEU L HG   1 
ATOM   4334 H HD11 . LEU B 2 75  ? 5.28373   7.20631   34.22811  1.000 20.44998  ? 73  LEU L HD11 1 
ATOM   4335 H HD12 . LEU B 2 75  ? 4.16009   7.73708   35.21768  1.000 20.44998  ? 73  LEU L HD12 1 
ATOM   4336 H HD13 . LEU B 2 75  ? 4.00576   6.31279   34.53131  1.000 20.44998  ? 73  LEU L HD13 1 
ATOM   4337 H HD21 . LEU B 2 75  ? 4.89206   7.15431   31.82105  1.000 21.67101  ? 73  LEU L HD21 1 
ATOM   4338 H HD22 . LEU B 2 75  ? 3.59550   6.25099   31.98368  1.000 21.67101  ? 73  LEU L HD22 1 
ATOM   4339 H HD23 . LEU B 2 75  ? 3.50647   7.63664   31.21195  1.000 21.67101  ? 73  LEU L HD23 1 
ATOM   4340 N N    . THR B 2 76  ? 2.85360   10.82978  34.92903  1.000 13.84351  ? 74  THR L N    1 
ATOM   4341 C CA   . THR B 2 76  ? 3.36442   12.16499  34.66937  1.000 14.95547  ? 74  THR L CA   1 
ATOM   4342 C C    . THR B 2 76  ? 4.85400   12.08186  34.36289  1.000 16.25988  ? 74  THR L C    1 
ATOM   4343 O O    . THR B 2 76  ? 5.61125   11.41990  35.08207  1.000 20.78842  ? 74  THR L O    1 
ATOM   4344 C CB   . THR B 2 76  ? 3.11157   13.08459  35.87027  1.000 21.80237  ? 74  THR L CB   1 
ATOM   4345 O OG1  . THR B 2 76  ? 1.70425   13.14714  36.13895  1.000 21.67772  ? 74  THR L OG1  1 
ATOM   4346 C CG2  . THR B 2 76  ? 3.63420   14.48882  35.60047  1.000 23.91149  ? 74  THR L CG2  1 
ATOM   4347 H H    . THR B 2 76  ? 3.21062   10.45777  35.61732  1.000 16.61905  ? 74  THR L H    1 
ATOM   4348 H HA   . THR B 2 76  ? 2.91989   12.54404  33.89503  1.000 17.95340  ? 74  THR L HA   1 
ATOM   4349 H HB   . THR B 2 76  ? 3.57708   12.73263  36.64508  1.000 26.16968  ? 74  THR L HB   1 
ATOM   4350 H HG1  . THR B 2 76  ? 1.29628   13.44258  35.46673  1.000 26.02010  ? 74  THR L HG1  1 
ATOM   4351 H HG21 . THR B 2 76  ? 3.33524   15.09367  36.29738  1.000 28.70062  ? 74  THR L HG21 1 
ATOM   4352 H HG22 . THR B 2 76  ? 4.60402   14.48409  35.58246  1.000 28.70062  ? 74  THR L HG22 1 
ATOM   4353 H HG23 . THR B 2 76  ? 3.30501   14.80670  34.74520  1.000 28.70062  ? 74  THR L HG23 1 
ATOM   4354 N N    . ILE B 2 77  ? 5.26405   12.74620  33.29109  1.000 14.36968  ? 75  ILE L N    1 
ATOM   4355 C CA   . ILE B 2 77  ? 6.66402   12.97991  32.97518  1.000 14.26632  ? 75  ILE L CA   1 
ATOM   4356 C C    . ILE B 2 77  ? 6.88315   14.47261  33.20053  1.000 15.10057  ? 75  ILE L C    1 
ATOM   4357 O O    . ILE B 2 77  ? 6.30516   15.30884  32.49369  1.000 16.45617  ? 75  ILE L O    1 
ATOM   4358 C CB   . ILE B 2 77  ? 7.01357   12.55335  31.54481  1.000 16.94358  ? 75  ILE L CB   1 
ATOM   4359 C CG1  . ILE B 2 77  ? 6.49886   11.13481  31.26996  1.000 16.48126  ? 75  ILE L CG1  1 
ATOM   4360 C CG2  . ILE B 2 77  ? 8.52414   12.59367  31.32531  1.000 16.58014  ? 75  ILE L CG2  1 
ATOM   4361 C CD1  . ILE B 2 77  ? 6.63661   10.69786  29.82097  1.000 17.06098  ? 75  ILE L CD1  1 
ATOM   4362 H H    . ILE B 2 77  ? 4.72779   13.08402  32.70980  1.000 17.25045  ? 75  ILE L H    1 
ATOM   4363 H HA   . ILE B 2 77  ? 7.24165   12.47497  33.56871  1.000 17.12642  ? 75  ILE L HA   1 
ATOM   4364 H HB   . ILE B 2 77  ? 6.58533   13.17532  30.93599  1.000 20.33913  ? 75  ILE L HB   1 
ATOM   4365 H HG12 . ILE B 2 77  ? 7.00189   10.51024  31.81565  1.000 19.78435  ? 75  ILE L HG12 1 
ATOM   4366 H HG13 . ILE B 2 77  ? 5.55788   11.09496  31.50204  1.000 19.78435  ? 75  ILE L HG13 1 
ATOM   4367 H HG21 . ILE B 2 77  ? 8.71286   12.40560  30.39262  1.000 19.90300  ? 75  ILE L HG21 1 
ATOM   4368 H HG22 . ILE B 2 77  ? 8.85365   13.47578  31.55813  1.000 19.90300  ? 75  ILE L HG22 1 
ATOM   4369 H HG23 . ILE B 2 77  ? 8.94313   11.92464  31.88900  1.000 19.90300  ? 75  ILE L HG23 1 
ATOM   4370 H HD11 . ILE B 2 77  ? 6.20422   9.83691   29.70828  1.000 20.48001  ? 75  ILE L HD11 1 
ATOM   4371 H HD12 . ILE B 2 77  ? 6.21290   11.35802  29.25040  1.000 20.48001  ? 75  ILE L HD12 1 
ATOM   4372 H HD13 . ILE B 2 77  ? 7.57860   10.62624  29.60091  1.000 20.48001  ? 75  ILE L HD13 1 
ATOM   4373 N N    . SER B 2 78  ? 7.66611   14.81020  34.22595  1.000 15.63069  ? 76  SER L N    1 
ATOM   4374 C CA   . SER B 2 78  ? 7.79322   16.21003  34.61783  1.000 17.09927  ? 76  SER L CA   1 
ATOM   4375 C C    . SER B 2 78  ? 8.50311   17.03218  33.55035  1.000 21.46116  ? 76  SER L C    1 
ATOM   4376 O O    . SER B 2 78  ? 8.18558   18.21272  33.36580  1.000 19.41980  ? 76  SER L O    1 
ATOM   4377 C CB   . SER B 2 78  ? 8.53534   16.31196  35.94972  1.000 20.05917  ? 76  SER L CB   1 
ATOM   4378 O OG   . SER B 2 78  ? 9.84947   15.78986  35.83963  1.000 21.81915  ? 76  SER L OG   1 
ATOM   4379 H H    . SER B 2 78  ? 8.12447   14.25875  34.70073  1.000 18.76366  ? 76  SER L H    1 
ATOM   4380 H HA   . SER B 2 78  ? 6.90591   16.58310  34.73785  1.000 20.52596  ? 76  SER L HA   1 
ATOM   4381 H HB2  . SER B 2 78  ? 8.58751   17.24465  36.21100  1.000 24.07784  ? 76  SER L HB2  1 
ATOM   4382 H HB3  . SER B 2 78  ? 8.05031   15.80617  36.62041  1.000 24.07784  ? 76  SER L HB3  1 
ATOM   4383 H HG   . SER B 2 78  ? 10.24730  15.85536  36.57654  1.000 26.18981  ? 76  SER L HG   1 
ATOM   4384 N N    . SER B 2 79  ? 9.46287   16.43440  32.84627  1.000 17.13413  ? 77  SER L N    1 
ATOM   4385 C CA   . SER B 2 79  ? 10.25149  17.16026  31.85347  1.000 19.07266  ? 77  SER L CA   1 
ATOM   4386 C C    . SER B 2 79  ? 10.74524  16.13465  30.83625  1.000 18.55354  ? 77  SER L C    1 
ATOM   4387 O O    . SER B 2 79  ? 11.66729  15.37111  31.12419  1.000 18.53136  ? 77  SER L O    1 
ATOM   4388 C CB   . SER B 2 79  ? 11.40775  17.90271  32.50338  1.000 27.04487  ? 77  SER L CB   1 
ATOM   4389 O OG   . SER B 2 79  ? 12.21042  18.55520  31.53549  1.000 28.53309  ? 77  SER L OG   1 
ATOM   4390 H H    . SER B 2 79  ? 9.67741   15.60538  32.92559  1.000 20.56778  ? 77  SER L H    1 
ATOM   4391 H HA   . SER B 2 79  ? 9.68858   17.80776  31.40095  1.000 22.89403  ? 77  SER L HA   1 
ATOM   4392 H HB2  . SER B 2 79  ? 11.05081  18.56645  33.11407  1.000 32.46068  ? 77  SER L HB2  1 
ATOM   4393 H HB3  . SER B 2 79  ? 11.95614  17.26645  32.98849  1.000 32.46068  ? 77  SER L HB3  1 
ATOM   4394 H HG   . SER B 2 79  ? 12.57769  17.98760  31.03694  1.000 34.24654  ? 77  SER L HG   1 
ATOM   4395 N N    . LEU B 2 80  ? 10.12428  16.13669  29.66218  1.000 17.07829  ? 78  LEU L N    1 
ATOM   4396 C CA   . LEU B 2 80  ? 10.37849  15.11444  28.65541  1.000 17.45030  ? 78  LEU L CA   1 
ATOM   4397 C C    . LEU B 2 80  ? 11.82129  15.15440  28.16202  1.000 20.44869  ? 78  LEU L C    1 
ATOM   4398 O O    . LEU B 2 80  ? 12.37577  16.22214  27.89374  1.000 20.30081  ? 78  LEU L O    1 
ATOM   4399 C CB   . LEU B 2 80  ? 9.41687   15.33063  27.48846  1.000 19.23844  ? 78  LEU L CB   1 
ATOM   4400 C CG   . LEU B 2 80  ? 9.18471   14.22888  26.47332  1.000 21.97727  ? 78  LEU L CG   1 
ATOM   4401 C CD1  . LEU B 2 80  ? 8.56037   13.01951  27.11896  1.000 21.39190  ? 78  LEU L CD1  1 
ATOM   4402 C CD2  . LEU B 2 80  ? 8.28461   14.77939  25.37980  1.000 26.43479  ? 78  LEU L CD2  1 
ATOM   4403 H H    . LEU B 2 80  ? 9.54510   16.72482  29.42079  1.000 20.50079  ? 78  LEU L H    1 
ATOM   4404 H HA   . LEU B 2 80  ? 10.23556  14.23532  29.03962  1.000 20.94719  ? 78  LEU L HA   1 
ATOM   4405 H HB2  . LEU B 2 80  ? 8.54768   15.53244  27.86881  1.000 23.09297  ? 78  LEU L HB2  1 
ATOM   4406 H HB3  . LEU B 2 80  ? 9.74450   16.09323  26.98646  1.000 23.09297  ? 78  LEU L HB3  1 
ATOM   4407 H HG   . LEU B 2 80  ? 10.02794  13.93833  26.09193  1.000 26.37956  ? 78  LEU L HG   1 
ATOM   4408 H HD11 . LEU B 2 80  ? 8.36291   12.36217  26.43353  1.000 25.67712  ? 78  LEU L HD11 1 
ATOM   4409 H HD12 . LEU B 2 80  ? 9.18332   12.64857  27.76335  1.000 25.67712  ? 78  LEU L HD12 1 
ATOM   4410 H HD13 . LEU B 2 80  ? 7.74223   13.28720  27.56604  1.000 25.67712  ? 78  LEU L HD13 1 
ATOM   4411 H HD21 . LEU B 2 80  ? 8.05723   14.06249  24.76722  1.000 31.72858  ? 78  LEU L HD21 1 
ATOM   4412 H HD22 . LEU B 2 80  ? 7.47873   15.13692  25.78431  1.000 31.72858  ? 78  LEU L HD22 1 
ATOM   4413 H HD23 . LEU B 2 80  ? 8.75669   15.48199  24.90610  1.000 31.72858  ? 78  LEU L HD23 1 
ATOM   4414 N N    . GLN B 2 81  ? 12.42693  13.97864  28.03022  1.000 16.94982  ? 79  GLN L N    1 
ATOM   4415 C CA   . GLN B 2 81  ? 13.74728  13.83079  27.43768  1.000 18.53394  ? 79  GLN L CA   1 
ATOM   4416 C C    . GLN B 2 81  ? 13.63574  13.17898  26.06575  1.000 21.51320  ? 79  GLN L C    1 
ATOM   4417 O O    . GLN B 2 81  ? 12.64145  12.50787  25.76765  1.000 18.17802  ? 79  GLN L O    1 
ATOM   4418 C CB   . GLN B 2 81  ? 14.66660  12.98555  28.33109  1.000 22.08440  ? 79  GLN L CB   1 
ATOM   4419 C CG   . GLN B 2 81  ? 15.13527  13.68695  29.60351  1.000 24.70250  ? 79  GLN L CG   1 
ATOM   4420 C CD   . GLN B 2 81  ? 16.05314  14.86799  29.32106  1.000 28.22934  ? 79  GLN L CD   1 
ATOM   4421 O OE1  . GLN B 2 81  ? 15.81312  15.98042  29.78997  1.000 38.85333  ? 79  GLN L OE1  1 
ATOM   4422 N NE2  . GLN B 2 81  ? 17.11224  14.62527  28.55999  1.000 30.35071  ? 79  GLN L NE2  1 
ATOM   4423 H H    . GLN B 2 81  ? 12.08126  13.23332  28.28440  1.000 20.34662  ? 79  GLN L H    1 
ATOM   4424 H HA   . GLN B 2 81  ? 14.15747  14.70450  27.34130  1.000 22.24756  ? 79  GLN L HA   1 
ATOM   4425 H HB2  . GLN B 2 81  ? 14.18744  12.18536  28.59754  1.000 26.50811  ? 79  GLN L HB2  1 
ATOM   4426 H HB3  . GLN B 2 81  ? 15.45625  12.74521  27.82159  1.000 26.50811  ? 79  GLN L HB3  1 
ATOM   4427 H HG2  . GLN B 2 81  ? 14.36119  14.01732  30.08574  1.000 29.64983  ? 79  GLN L HG2  1 
ATOM   4428 H HG3  . GLN B 2 81  ? 15.62257  13.05303  30.15268  1.000 29.64983  ? 79  GLN L HG3  1 
ATOM   4429 H HE21 . GLN B 2 81  ? 17.25002  13.83313  28.25483  1.000 36.42768  ? 79  GLN L HE21 1 
ATOM   4430 H HE22 . GLN B 2 81  ? 17.66106  15.26007  28.37176  1.000 36.42768  ? 79  GLN L HE22 1 
ATOM   4431 N N    . PRO B 2 82  ? 14.63860  13.35600  25.19886  1.000 21.26240  ? 80  PRO L N    1 
ATOM   4432 C CA   . PRO B 2 82  ? 14.54854  12.75657  23.85506  1.000 19.27304  ? 80  PRO L CA   1 
ATOM   4433 C C    . PRO B 2 82  ? 14.44831  11.24559  23.88544  1.000 20.27269  ? 80  PRO L C    1 
ATOM   4434 O O    . PRO B 2 82  ? 13.82628  10.65276  22.99454  1.000 19.45375  ? 80  PRO L O    1 
ATOM   4435 C CB   . PRO B 2 82  ? 15.84198  13.22205  23.16728  1.000 25.55080  ? 80  PRO L CB   1 
ATOM   4436 C CG   . PRO B 2 82  ? 16.32236  14.39509  23.97468  1.000 23.50761  ? 80  PRO L CG   1 
ATOM   4437 C CD   . PRO B 2 82  ? 15.88993  14.11664  25.38368  1.000 21.76765  ? 80  PRO L CD   1 
ATOM   4438 H HA   . PRO B 2 82  ? 13.78728  13.12432  23.37952  1.000 23.13448  ? 80  PRO L HA   1 
ATOM   4439 H HB2  . PRO B 2 82  ? 16.49537  12.50518  23.17637  1.000 30.66779  ? 80  PRO L HB2  1 
ATOM   4440 H HB3  . PRO B 2 82  ? 15.65167  13.48592  22.25347  1.000 30.66779  ? 80  PRO L HB3  1 
ATOM   4441 H HG2  . PRO B 2 82  ? 17.28846  14.46002  23.91702  1.000 28.21596  ? 80  PRO L HG2  1 
ATOM   4442 H HG3  . PRO B 2 82  ? 15.91470  15.21069  23.64375  1.000 28.21596  ? 80  PRO L HG3  1 
ATOM   4443 H HD2  . PRO B 2 82  ? 16.55303  13.58527  25.85148  1.000 26.12801  ? 80  PRO L HD2  1 
ATOM   4444 H HD3  . PRO B 2 82  ? 15.72606  14.94222  25.86583  1.000 26.12801  ? 80  PRO L HD3  1 
ATOM   4445 N N    . GLU B 2 83  ? 15.02491  10.59879  24.89282  1.000 20.17140  ? 81  GLU L N    1 
ATOM   4446 C CA   . GLU B 2 83  ? 14.96044  9.14535   24.97920  1.000 25.67252  ? 81  GLU L CA   1 
ATOM   4447 C C    . GLU B 2 83  ? 13.59791  8.64299   25.43727  1.000 20.72718  ? 81  GLU L C    1 
ATOM   4448 O O    . GLU B 2 83  ? 13.39573  7.42602   25.50494  1.000 19.86158  ? 81  GLU L O    1 
ATOM   4449 C CB   . GLU B 2 83  ? 16.05115  8.61936   25.91947  1.000 28.24786  ? 81  GLU L CB   1 
ATOM   4450 C CG   . GLU B 2 83  ? 16.07461  9.25655   27.30960  1.000 29.32127  ? 81  GLU L CG   1 
ATOM   4451 C CD   . GLU B 2 83  ? 17.01155  10.46158  27.40233  1.000 37.59447  ? 81  GLU L CD   1 
ATOM   4452 O OE1  . GLU B 2 83  ? 17.21302  11.14863  26.37561  1.000 29.55006  ? 81  GLU L OE1  1 
ATOM   4453 O OE2  . GLU B 2 83  ? 17.54256  10.72185  28.50724  1.000 43.13658  ? 81  GLU L OE2  1 
ATOM   4454 H H    . GLU B 2 83  ? 15.45610  10.97678  25.53375  1.000 24.21252  ? 81  GLU L H    1 
ATOM   4455 H HA   . GLU B 2 83  ? 15.13237  8.77643   24.09873  1.000 30.81385  ? 81  GLU L HA   1 
ATOM   4456 H HB2  . GLU B 2 83  ? 15.91836  7.66603   26.03958  1.000 33.90427  ? 81  GLU L HB2  1 
ATOM   4457 H HB3  . GLU B 2 83  ? 16.91466  8.78504   25.50985  1.000 33.90427  ? 81  GLU L HB3  1 
ATOM   4458 H HG2  . GLU B 2 83  ? 15.17971  9.55651   27.53340  1.000 35.19236  ? 81  GLU L HG2  1 
ATOM   4459 H HG3  . GLU B 2 83  ? 16.37378  8.59576   27.95362  1.000 35.19236  ? 81  GLU L HG3  1 
ATOM   4460 N N    . ASP B 2 84  ? 12.66259  9.53808   25.73731  1.000 19.11753  ? 82  ASP L N    1 
ATOM   4461 C CA   . ASP B 2 84  ? 11.35324  9.15448   26.24514  1.000 18.28904  ? 82  ASP L CA   1 
ATOM   4462 C C    . ASP B 2 84  ? 10.34764  8.84892   25.14062  1.000 18.21790  ? 82  ASP L C    1 
ATOM   4463 O O    . ASP B 2 84  ? 9.20215   8.49993   25.44653  1.000 15.49547  ? 82  ASP L O    1 
ATOM   4464 C CB   . ASP B 2 84  ? 10.81628  10.25833  27.16149  1.000 17.20979  ? 82  ASP L CB   1 
ATOM   4465 C CG   . ASP B 2 84  ? 11.62429  10.39210  28.43988  1.000 16.34405  ? 82  ASP L CG   1 
ATOM   4466 O OD1  . ASP B 2 84  ? 12.41392  9.47410   28.73483  1.000 19.21121  ? 82  ASP L OD1  1 
ATOM   4467 O OD2  . ASP B 2 84  ? 11.47576  11.40628  29.15076  1.000 18.43136  ? 82  ASP L OD2  1 
ATOM   4468 H H    . ASP B 2 84  ? 12.76563  10.38775  25.65338  1.000 22.94787  ? 82  ASP L H    1 
ATOM   4469 H HA   . ASP B 2 84  ? 11.44404  8.34661   26.77429  1.000 21.95368  ? 82  ASP L HA   1 
ATOM   4470 H HB2  . ASP B 2 84  ? 10.85222  11.10633  26.69191  1.000 20.65858  ? 82  ASP L HB2  1 
ATOM   4471 H HB3  . ASP B 2 84  ? 9.90005   10.05198  27.40405  1.000 20.65858  ? 82  ASP L HB3  1 
ATOM   4472 N N    . PHE B 2 85  ? 10.73477  8.95226   23.87372  1.000 14.63886  ? 83  PHE L N    1 
ATOM   4473 C CA   . PHE B 2 85  ? 9.83377   8.52751   22.81055  1.000 17.31612  ? 83  PHE L CA   1 
ATOM   4474 C C    . PHE B 2 85  ? 9.58655   7.02977   22.93462  1.000 18.43116  ? 83  PHE L C    1 
ATOM   4475 O O    . PHE B 2 85  ? 10.52401  6.23694   23.10287  1.000 17.74838  ? 83  PHE L O    1 
ATOM   4476 C CB   . PHE B 2 85  ? 10.40139  8.88313   21.43525  1.000 24.62320  ? 83  PHE L CB   1 
ATOM   4477 C CG   . PHE B 2 85  ? 11.31383  7.84814   20.85463  1.000 26.00237  ? 83  PHE L CG   1 
ATOM   4478 C CD1  . PHE B 2 85  ? 10.81066  6.82839   20.06805  1.000 30.87643  ? 83  PHE L CD1  1 
ATOM   4479 C CD2  . PHE B 2 85  ? 12.68200  7.91215   21.07155  1.000 33.74986  ? 83  PHE L CD2  1 
ATOM   4480 C CE1  . PHE B 2 85  ? 11.64583  5.87554   19.52294  1.000 37.31347  ? 83  PHE L CE1  1 
ATOM   4481 C CE2  . PHE B 2 85  ? 13.52797  6.96273   20.52760  1.000 38.41912  ? 83  PHE L CE2  1 
ATOM   4482 C CZ   . PHE B 2 85  ? 13.00776  5.94184   19.74984  1.000 41.47844  ? 83  PHE L CZ   1 
ATOM   4483 H H    . PHE B 2 85  ? 11.49449  9.25714   23.61013  1.000 17.57346  ? 83  PHE L H    1 
ATOM   4484 H HA   . PHE B 2 85  ? 8.98692   8.99405   22.88852  1.000 20.78618  ? 83  PHE L HA   1 
ATOM   4485 H HB2  . PHE B 2 85  ? 9.66307   9.00256   20.81757  1.000 29.55467  ? 83  PHE L HB2  1 
ATOM   4486 H HB3  . PHE B 2 85  ? 10.90575  9.70805   21.51287  1.000 29.55467  ? 83  PHE L HB3  1 
ATOM   4487 H HD1  . PHE B 2 85  ? 9.89627   6.78432   19.90423  1.000 37.05856  ? 83  PHE L HD1  1 
ATOM   4488 H HD2  . PHE B 2 85  ? 13.03434  8.60056   21.58812  1.000 40.50667  ? 83  PHE L HD2  1 
ATOM   4489 H HE1  . PHE B 2 85  ? 11.29314  5.18947   19.00350  1.000 44.78300  ? 83  PHE L HE1  1 
ATOM   4490 H HE2  . PHE B 2 85  ? 14.44357  7.00981   20.68370  1.000 46.10978  ? 83  PHE L HE2  1 
ATOM   4491 H HZ   . PHE B 2 85  ? 13.57339  5.30234   19.38105  1.000 49.78096  ? 83  PHE L HZ   1 
ATOM   4492 N N    . ALA B 2 86  ? 8.31877   6.64166   22.86081  1.000 19.57110  ? 84  ALA L N    1 
ATOM   4493 C CA   . ALA B 2 86  ? 7.96733   5.25445   23.14718  1.000 19.53497  ? 84  ALA L CA   1 
ATOM   4494 C C    . ALA B 2 86  ? 6.46327   5.08545   23.14774  1.000 15.42141  ? 84  ALA L C    1 
ATOM   4495 O O    . ALA B 2 86  ? 5.73433   6.07430   23.09031  1.000 17.63385  ? 84  ALA L O    1 
ATOM   4496 C CB   . ALA B 2 86  ? 8.51123   4.81045   24.50988  1.000 15.72563  ? 84  ALA L CB   1 
ATOM   4497 H H    . ALA B 2 86  ? 7.65757   7.15031   22.65182  1.000 23.49215  ? 84  ALA L H    1 
ATOM   4498 H HA   . ALA B 2 86  ? 8.36307   4.69419   22.46132  1.000 23.44880  ? 84  ALA L HA   1 
ATOM   4499 H HB1  . ALA B 2 86  ? 8.14819   3.93718   24.72550  1.000 18.87759  ? 84  ALA L HB1  1 
ATOM   4500 H HB2  . ALA B 2 86  ? 9.47903   4.76415   24.46376  1.000 18.87759  ? 84  ALA L HB2  1 
ATOM   4501 H HB3  . ALA B 2 86  ? 8.24262   5.45563   25.18255  1.000 18.87759  ? 84  ALA L HB3  1 
ATOM   4502 N N    . THR B 2 87  ? 5.97737   3.85572   23.25284  1.000 14.12876  ? 85  THR L N    1 
ATOM   4503 C CA   . THR B 2 87  ? 4.57254   3.62869   23.55904  1.000 13.42539  ? 85  THR L CA   1 
ATOM   4504 C C    . THR B 2 87  ? 4.46533   3.26781   25.03493  1.000 14.90438  ? 85  THR L C    1 
ATOM   4505 O O    . THR B 2 87  ? 5.16695   2.37324   25.51865  1.000 17.13239  ? 85  THR L O    1 
ATOM   4506 C CB   . THR B 2 87  ? 3.97908   2.54691   22.66015  1.000 19.30696  ? 85  THR L CB   1 
ATOM   4507 O OG1  . THR B 2 87  ? 4.04770   2.99038   21.29646  1.000 17.08027  ? 85  THR L OG1  1 
ATOM   4508 C CG2  . THR B 2 87  ? 2.53432   2.30382   23.00700  1.000 19.21885  ? 85  THR L CG2  1 
ATOM   4509 H H    . THR B 2 87  ? 6.44116   3.13866   23.15120  1.000 16.96135  ? 85  THR L H    1 
ATOM   4510 H HA   . THR B 2 87  ? 4.04940   4.43019   23.40148  1.000 16.11730  ? 85  THR L HA   1 
ATOM   4511 H HB   . THR B 2 87  ? 4.47171   1.71952   22.77692  1.000 23.17518  ? 85  THR L HB   1 
ATOM   4512 H HG1  . THR B 2 87  ? 3.73835   2.39918   20.78618  1.000 20.50316  ? 85  THR L HG1  1 
ATOM   4513 H HG21 . THR B 2 87  ? 2.13912   1.68856   22.36968  1.000 23.06946  ? 85  THR L HG21 1 
ATOM   4514 H HG22 . THR B 2 87  ? 2.46625   1.92262   23.89635  1.000 23.06946  ? 85  THR L HG22 1 
ATOM   4515 H HG23 . THR B 2 87  ? 2.04251   3.13959   22.98425  1.000 23.06946  ? 85  THR L HG23 1 
ATOM   4516 N N    . TYR B 2 88  ? 3.62484   3.99740   25.75201  1.000 12.16291  ? 86  TYR L N    1 
ATOM   4517 C CA   . TYR B 2 88  ? 3.43477   3.81739   27.18304  1.000 12.59987  ? 86  TYR L CA   1 
ATOM   4518 C C    . TYR B 2 88  ? 2.15845   3.03093   27.42994  1.000 15.94140  ? 86  TYR L C    1 
ATOM   4519 O O    . TYR B 2 88  ? 1.11672   3.32167   26.83145  1.000 16.42456  ? 86  TYR L O    1 
ATOM   4520 C CB   . TYR B 2 88  ? 3.38873   5.17422   27.88791  1.000 13.77770  ? 86  TYR L CB   1 
ATOM   4521 C CG   . TYR B 2 88  ? 4.72829   5.84863   27.87193  1.000 12.95991  ? 86  TYR L CG   1 
ATOM   4522 C CD1  . TYR B 2 88  ? 5.13784   6.60648   26.77343  1.000 15.22479  ? 86  TYR L CD1  1 
ATOM   4523 C CD2  . TYR B 2 88  ? 5.61095   5.69527   28.92435  1.000 13.26092  ? 86  TYR L CD2  1 
ATOM   4524 C CE1  . TYR B 2 88  ? 6.38321   7.20330   26.74753  1.000 13.80242  ? 86  TYR L CE1  1 
ATOM   4525 C CE2  . TYR B 2 88  ? 6.85646   6.28679   28.90380  1.000 16.60644  ? 86  TYR L CE2  1 
ATOM   4526 C CZ   . TYR B 2 88  ? 7.23753   7.03970   27.82029  1.000 17.42479  ? 86  TYR L CZ   1 
ATOM   4527 O OH   . TYR B 2 88  ? 8.48217   7.62227   27.81912  1.000 15.42679  ? 86  TYR L OH   1 
ATOM   4528 H H    . TYR B 2 88  ? 3.13701   4.62386   25.42160  1.000 14.60232  ? 86  TYR L H    1 
ATOM   4529 H HA   . TYR B 2 88  ? 4.17147   3.30886   27.55664  1.000 15.12668  ? 86  TYR L HA   1 
ATOM   4530 H HB2  . TYR B 2 88  ? 2.75190   5.74903   27.43519  1.000 16.54008  ? 86  TYR L HB2  1 
ATOM   4531 H HB3  . TYR B 2 88  ? 3.12201   5.04648   28.81173  1.000 16.54008  ? 86  TYR L HB3  1 
ATOM   4532 H HD1  . TYR B 2 88  ? 4.56415   6.71098   26.04895  1.000 18.27658  ? 86  TYR L HD1  1 
ATOM   4533 H HD2  . TYR B 2 88  ? 5.36039   5.18392   29.65963  1.000 15.91993  ? 86  TYR L HD2  1 
ATOM   4534 H HE1  . TYR B 2 88  ? 6.64437   7.71125   26.01358  1.000 16.56974  ? 86  TYR L HE1  1 
ATOM   4535 H HE2  . TYR B 2 88  ? 7.43696   6.17614   29.62191  1.000 19.93457  ? 86  TYR L HE2  1 
ATOM   4536 H HH   . TYR B 2 88  ? 8.59733   8.05251   27.10692  1.000 18.51898  ? 86  TYR L HH   1 
ATOM   4537 N N    . TYR B 2 89  ? 2.24558   2.03962   28.31251  1.000 14.13234  ? 87  TYR L N    1 
ATOM   4538 C CA   . TYR B 2 89  ? 1.14399   1.14184   28.61859  1.000 13.77880  ? 87  TYR L CA   1 
ATOM   4539 C C    . TYR B 2 89  ? 0.84156   1.12259   30.11062  1.000 17.65260  ? 87  TYR L C    1 
ATOM   4540 O O    . TYR B 2 89  ? 1.76034   1.03918   30.93643  1.000 16.19389  ? 87  TYR L O    1 
ATOM   4541 C CB   . TYR B 2 89  ? 1.46837   -0.29577  28.20222  1.000 16.29308  ? 87  TYR L CB   1 
ATOM   4542 C CG   . TYR B 2 89  ? 1.49664   -0.56979  26.71574  1.000 14.85808  ? 87  TYR L CG   1 
ATOM   4543 C CD1  . TYR B 2 89  ? 0.34407   -0.94258  26.04141  1.000 13.70676  ? 87  TYR L CD1  1 
ATOM   4544 C CD2  . TYR B 2 89  ? 2.68043   -0.48737  25.99359  1.000 14.02445  ? 87  TYR L CD2  1 
ATOM   4545 C CE1  . TYR B 2 89  ? 0.36538   -1.20991  24.68978  1.000 14.91737  ? 87  TYR L CE1  1 
ATOM   4546 C CE2  . TYR B 2 89  ? 2.71192   -0.75920  24.63590  1.000 15.84334  ? 87  TYR L CE2  1 
ATOM   4547 C CZ   . TYR B 2 89  ? 1.55374   -1.11903  23.99037  1.000 16.34732  ? 87  TYR L CZ   1 
ATOM   4548 O OH   . TYR B 2 89  ? 1.58329   -1.38996  22.63576  1.000 20.96721  ? 87  TYR L OH   1 
ATOM   4549 H H    . TYR B 2 89  ? 2.95853   1.86406   28.76026  1.000 16.96565  ? 87  TYR L H    1 
ATOM   4550 H HA   . TYR B 2 89  ? 0.36398   1.46888   28.14368  1.000 16.54139  ? 87  TYR L HA   1 
ATOM   4551 H HB2  . TYR B 2 89  ? 2.34507   -0.52101  28.55088  1.000 19.55853  ? 87  TYR L HB2  1 
ATOM   4552 H HB3  . TYR B 2 89  ? 0.79764   -0.88087  28.58779  1.000 19.55853  ? 87  TYR L HB3  1 
ATOM   4553 H HD1  . TYR B 2 89  ? -0.45669  -1.01341  26.50902  1.000 16.45495  ? 87  TYR L HD1  1 
ATOM   4554 H HD2  . TYR B 2 89  ? 3.46556   -0.24543  26.42942  1.000 16.83617  ? 87  TYR L HD2  1 
ATOM   4555 H HE1  . TYR B 2 89  ? -0.41764  -1.45077  24.24959  1.000 17.90767  ? 87  TYR L HE1  1 
ATOM   4556 H HE2  . TYR B 2 89  ? 3.51134   -0.69860  24.16457  1.000 19.01884  ? 87  TYR L HE2  1 
ATOM   4557 H HH   . TYR B 2 89  ? 2.36608   -1.30572  22.34294  1.000 25.16748  ? 87  TYR L HH   1 
ATOM   4558 N N    A CYS B 2 90  ? -0.45119  1.20435   30.45257  0.429 15.47820  ? 88  CYS L N    1 
ATOM   4559 N N    B CYS B 2 90  ? -0.43740  1.17326   30.44972  0.571 15.60394  ? 88  CYS L N    1 
ATOM   4560 C CA   A CYS B 2 90  ? -0.92547  0.90217   31.80249  0.429 19.00529  ? 88  CYS L CA   1 
ATOM   4561 C CA   B CYS B 2 90  ? -0.88317  0.90125   31.80786  0.571 19.13717  ? 88  CYS L CA   1 
ATOM   4562 C C    A CYS B 2 90  ? -1.25987  -0.58307  31.85746  0.429 17.58944  ? 88  CYS L C    1 
ATOM   4563 C C    B CYS B 2 90  ? -1.26405  -0.57069  31.86821  0.571 17.51145  ? 88  CYS L C    1 
ATOM   4564 O O    A CYS B 2 90  ? -1.86755  -1.12167  30.92822  0.429 15.39301  ? 88  CYS L O    1 
ATOM   4565 O O    B CYS B 2 90  ? -1.88875  -1.09274  30.94148  0.571 15.65632  ? 88  CYS L O    1 
ATOM   4566 C CB   A CYS B 2 90  ? -2.15589  1.74033   32.20067  0.429 19.66385  ? 88  CYS L CB   1 
ATOM   4567 C CB   B CYS B 2 90  ? -2.06321  1.79730   32.18044  0.571 19.68950  ? 88  CYS L CB   1 
ATOM   4568 S SG   A CYS B 2 90  ? -3.57132  1.78725   31.02927  0.429 14.35497  ? 88  CYS L SG   1 
ATOM   4569 S SG   B CYS B 2 90  ? -2.54572  1.73870   33.91236  0.571 20.89607  ? 88  CYS L SG   1 
ATOM   4570 H H    A CYS B 2 90  ? -1.07790  1.43585   29.91104  0.429 18.58068  ? 88  CYS L H    1 
ATOM   4571 H H    B CYS B 2 90  ? -1.07464  1.36522   29.90504  0.571 18.73157  ? 88  CYS L H    1 
ATOM   4572 H HA   A CYS B 2 90  ? -0.23605  1.12046   32.44898  0.429 22.81318  ? 88  CYS L HA   1 
ATOM   4573 H HA   B CYS B 2 90  ? -0.18831  1.08465   32.45934  0.571 22.97144  ? 88  CYS L HA   1 
ATOM   4574 H HB2  A CYS B 2 90  ? -2.49708  1.38719   33.03720  0.429 23.60346  ? 88  CYS L HB2  1 
ATOM   4575 H HB2  B CYS B 2 90  ? -1.82798  2.71564   31.97496  0.571 23.63423  ? 88  CYS L HB2  1 
ATOM   4576 H HB3  A CYS B 2 90  ? -1.86334  2.65713   32.32232  0.429 23.60346  ? 88  CYS L HB3  1 
ATOM   4577 H HB3  B CYS B 2 90  ? -2.83217  1.52626   31.65496  0.571 23.63423  ? 88  CYS L HB3  1 
ATOM   4578 H HG   B CYS B 2 90  ? -3.49015  2.45990   34.07942  0.571 25.08212  ? 88  CYS L HG   1 
ATOM   4579 N N    . VAL B 2 91  ? -0.83541  -1.25110  32.92920  1.000 17.12778  ? 89  VAL L N    1 
ATOM   4580 C CA   . VAL B 2 91  ? -1.05113  -2.68577  33.08741  1.000 18.35783  ? 89  VAL L CA   1 
ATOM   4581 C C    . VAL B 2 91  ? -1.67240  -2.91791  34.45160  1.000 18.20737  ? 89  VAL L C    1 
ATOM   4582 O O    . VAL B 2 91  ? -1.10824  -2.50370  35.47005  1.000 15.55348  ? 89  VAL L O    1 
ATOM   4583 C CB   . VAL B 2 91  ? 0.25221   -3.49026  32.95048  1.000 19.22230  ? 89  VAL L CB   1 
ATOM   4584 C CG1  . VAL B 2 91  ? -0.02881  -4.98731  33.03405  1.000 18.92427  ? 89  VAL L CG1  1 
ATOM   4585 C CG2  . VAL B 2 91  ? 0.96060   -3.14044  31.64533  1.000 21.41890  ? 89  VAL L CG2  1 
ATOM   4586 H H    A VAL B 2 91  ? -0.41458  -0.88858  33.58577  0.429 20.56017  ? 89  VAL L H    1 
ATOM   4587 H H    B VAL B 2 91  ? -0.40771  -0.89446  33.58455  0.571 20.56017  ? 89  VAL L H    1 
ATOM   4588 H HA   . VAL B 2 91  ? -1.67200  -2.99006  32.40709  1.000 22.03623  ? 89  VAL L HA   1 
ATOM   4589 H HB   . VAL B 2 91  ? 0.84330   -3.25793  33.68365  1.000 23.07359  ? 89  VAL L HB   1 
ATOM   4590 H HG11 . VAL B 2 91  ? 0.78156   -5.47345  32.81525  1.000 22.71596  ? 89  VAL L HG11 1 
ATOM   4591 H HG12 . VAL B 2 91  ? -0.31225  -5.20558  33.93567  1.000 22.71596  ? 89  VAL L HG12 1 
ATOM   4592 H HG13 . VAL B 2 91  ? -0.73028  -5.21265  32.40312  1.000 22.71596  ? 89  VAL L HG13 1 
ATOM   4593 H HG21 . VAL B 2 91  ? 1.55399   -3.86853  31.40309  1.000 25.70951  ? 89  VAL L HG21 1 
ATOM   4594 H HG22 . VAL B 2 91  ? 0.29635   -3.00998  30.95060  1.000 25.70951  ? 89  VAL L HG22 1 
ATOM   4595 H HG23 . VAL B 2 91  ? 1.47138   -2.32557  31.77182  1.000 25.70951  ? 89  VAL L HG23 1 
ATOM   4596 N N    . GLY B 2 92  ? -2.81895  -3.58587  34.47442  1.000 15.44239  ? 90  GLY L N    1 
ATOM   4597 C CA   . GLY B 2 92  ? -3.52716  -3.86491  35.70527  1.000 14.09773  ? 90  GLY L CA   1 
ATOM   4598 C C    . GLY B 2 92  ? -3.63236  -5.35357  35.96868  1.000 12.92523  ? 90  GLY L C    1 
ATOM   4599 O O    . GLY B 2 92  ? -3.67095  -6.16414  35.04021  1.000 13.94481  ? 90  GLY L O    1 
ATOM   4600 H H    . GLY B 2 92  ? -3.21123  -3.89223  33.77309  1.000 18.53771  ? 90  GLY L H    1 
ATOM   4601 H HA2  . GLY B 2 92  ? -3.05928  -3.45309  36.44850  1.000 16.92412  ? 90  GLY L HA2  1 
ATOM   4602 H HA3  . GLY B 2 92  ? -4.42334  -3.49735  35.65361  1.000 16.92412  ? 90  GLY L HA3  1 
ATOM   4603 N N    . HIS B 2 93  ? -3.66804  -5.70510  37.25360  1.000 13.89697  ? 91  HIS L N    1 
ATOM   4604 C CA   . HIS B 2 93  ? -3.90042  -7.06347  37.72772  1.000 16.76137  ? 91  HIS L CA   1 
ATOM   4605 C C    . HIS B 2 93  ? -5.25338  -7.10906  38.42649  1.000 14.04178  ? 91  HIS L C    1 
ATOM   4606 O O    . HIS B 2 93  ? -5.58276  -6.20323  39.19707  1.000 15.06347  ? 91  HIS L O    1 
ATOM   4607 C CB   . HIS B 2 93  ? -2.78886  -7.49129  38.68891  1.000 16.29126  ? 91  HIS L CB   1 
ATOM   4608 C CG   . HIS B 2 93  ? -2.88172  -8.91312  39.14149  1.000 16.86541  ? 91  HIS L CG   1 
ATOM   4609 N ND1  . HIS B 2 93  ? -2.94218  -9.97201  38.26054  1.000 16.37530  ? 91  HIS L ND1  1 
ATOM   4610 C CD2  . HIS B 2 93  ? -2.89698  -9.45400  40.38287  1.000 19.52567  ? 91  HIS L CD2  1 
ATOM   4611 C CE1  . HIS B 2 93  ? -2.99455  -11.10359 38.94000  1.000 16.39326  ? 91  HIS L CE1  1 
ATOM   4612 N NE2  . HIS B 2 93  ? -2.97151  -10.81654 40.22957  1.000 17.82164  ? 91  HIS L NE2  1 
ATOM   4613 H H    . HIS B 2 93  ? -3.55477  -5.14614  37.89728  1.000 16.68319  ? 91  HIS L H    1 
ATOM   4614 H HA   . HIS B 2 93  ? -3.91234  -7.69075  36.98794  1.000 20.12047  ? 91  HIS L HA   1 
ATOM   4615 H HB2  . HIS B 2 93  ? -1.93427  -7.37975  38.24378  1.000 19.55635  ? 91  HIS L HB2  1 
ATOM   4616 H HB3  . HIS B 2 93  ? -2.82785  -6.92853  39.47801  1.000 19.55635  ? 91  HIS L HB3  1 
ATOM   4617 H HD1  . HIS B 2 93  ? -2.94531  -9.90610  37.40308  1.000 19.65719  ? 91  HIS L HD1  1 
ATOM   4618 H HD2  . HIS B 2 93  ? -2.86331  -8.98981  41.18804  1.000 23.43764  ? 91  HIS L HD2  1 
ATOM   4619 H HE1  . HIS B 2 93  ? -3.03991  -11.95699 38.57318  1.000 19.67874  ? 91  HIS L HE1  1 
ATOM   4620 N N    . TYR B 2 94  ? -6.03500  -8.16238  38.16038  1.000 16.06352  ? 92  TYR L N    1 
ATOM   4621 C CA   . TYR B 2 94  ? -7.42882  -8.22911  38.58081  1.000 14.44957  ? 92  TYR L CA   1 
ATOM   4622 C C    . TYR B 2 94  ? -7.77466  -9.62961  39.05527  1.000 14.71770  ? 92  TYR L C    1 
ATOM   4623 O O    . TYR B 2 94  ? -7.17244  -10.61721 38.63239  1.000 15.70458  ? 92  TYR L O    1 
ATOM   4624 C CB   . TYR B 2 94  ? -8.39160  -7.87225  37.43836  1.000 20.72899  ? 92  TYR L CB   1 
ATOM   4625 C CG   . TYR B 2 94  ? -8.11838  -6.53346  36.82397  1.000 16.37921  ? 92  TYR L CG   1 
ATOM   4626 C CD1  . TYR B 2 94  ? -7.16220  -6.39105  35.83369  1.000 18.06854  ? 92  TYR L CD1  1 
ATOM   4627 C CD2  . TYR B 2 94  ? -8.80075  -5.40580  37.24998  1.000 17.21097  ? 92  TYR L CD2  1 
ATOM   4628 C CE1  . TYR B 2 94  ? -6.89975  -5.15635  35.27080  1.000 15.27269  ? 92  TYR L CE1  1 
ATOM   4629 C CE2  . TYR B 2 94  ? -8.54498  -4.17159  36.70230  1.000 19.43554  ? 92  TYR L CE2  1 
ATOM   4630 C CZ   . TYR B 2 94  ? -7.59590  -4.05007  35.71240  1.000 17.89450  ? 92  TYR L CZ   1 
ATOM   4631 O OH   . TYR B 2 94  ? -7.34842  -2.80991  35.16431  1.000 16.91628  ? 92  TYR L OH   1 
ATOM   4632 H H    . TYR B 2 94  ? -5.77170  -8.85915  37.73052  1.000 19.28306  ? 92  TYR L H    1 
ATOM   4633 H HA   . TYR B 2 94  ? -7.53971  -7.60709  39.31681  1.000 17.34632  ? 92  TYR L HA   1 
ATOM   4634 H HB2  . TYR B 2 94  ? -8.31121  -8.54146  36.74080  1.000 24.88162  ? 92  TYR L HB2  1 
ATOM   4635 H HB3  . TYR B 2 94  ? -9.29763  -7.86113  37.78460  1.000 24.88162  ? 92  TYR L HB3  1 
ATOM   4636 H HD1  . TYR B 2 94  ? -6.68931  -7.13711  35.54269  1.000 21.68908  ? 92  TYR L HD1  1 
ATOM   4637 H HD2  . TYR B 2 94  ? -9.44289  -5.48526  37.91800  1.000 20.66000  ? 92  TYR L HD2  1 
ATOM   4638 H HE1  . TYR B 2 94  ? -6.26015  -5.07207  34.60094  1.000 18.33407  ? 92  TYR L HE1  1 
ATOM   4639 H HE2  . TYR B 2 94  ? -9.01028  -3.42287  36.99861  1.000 23.32948  ? 92  TYR L HE2  1 
ATOM   4640 H HH   . TYR B 2 94  ? -6.73923  -2.86656  34.58874  1.000 20.30637  ? 92  TYR L HH   1 
ATOM   4641 N N    . GLY B 2 95  ? -8.79979  -9.70505  39.89886  1.000 16.23402  ? 93  GLY L N    1 
ATOM   4642 C CA   . GLY B 2 95  ? -9.43120  -10.97743 40.17472  1.000 19.32232  ? 93  GLY L CA   1 
ATOM   4643 C C    . GLY B 2 95  ? -9.86009  -11.19963 41.60732  1.000 19.90669  ? 93  GLY L C    1 
ATOM   4644 O O    . GLY B 2 95  ? -10.12990 -10.26005 42.35962  1.000 21.18535  ? 93  GLY L O    1 
ATOM   4645 H H    . GLY B 2 95  ? -9.14117  -9.03604  40.31778  1.000 19.48766  ? 93  GLY L H    1 
ATOM   4646 H HA2  . GLY B 2 95  ? -10.22178 -11.05584 39.61819  1.000 23.19362  ? 93  GLY L HA2  1 
ATOM   4647 H HA3  . GLY B 2 95  ? -8.81037  -11.68581 39.94303  1.000 23.19362  ? 93  GLY L HA3  1 
ATOM   4648 N N    . SER B 2 96  ? -9.93049  -12.47377 41.97486  1.000 20.45496  ? 94  SER L N    1 
ATOM   4649 C CA   . SER B 2 96  ? -10.28049 -12.92839 43.30749  1.000 20.00831  ? 94  SER L CA   1 
ATOM   4650 C C    . SER B 2 96  ? -9.34833  -14.07534 43.67608  1.000 23.07674  ? 94  SER L C    1 
ATOM   4651 O O    . SER B 2 96  ? -8.51887  -14.51440 42.86701  1.000 20.72491  ? 94  SER L O    1 
ATOM   4652 C CB   . SER B 2 96  ? -11.73768 -13.38625 43.34607  1.000 25.59697  ? 94  SER L CB   1 
ATOM   4653 O OG   . SER B 2 96  ? -11.88764 -14.51714 42.50253  1.000 26.73217  ? 94  SER L OG   1 
ATOM   4654 H H    . SER B 2 96  ? -9.77058  -13.12662 41.43837  1.000 24.55278  ? 94  SER L H    1 
ATOM   4655 H HA   . SER B 2 96  ? -10.15755 -12.20629 43.94338  1.000 24.01681  ? 94  SER L HA   1 
ATOM   4656 H HB2  . SER B 2 96  ? -11.97706 -13.62672 44.25479  1.000 30.72320  ? 94  SER L HB2  1 
ATOM   4657 H HB3  . SER B 2 96  ? -12.31022 -12.66954 43.03077  1.000 30.72320  ? 94  SER L HB3  1 
ATOM   4658 H HG   . SER B 2 96  ? -12.68335 -14.78569 42.52080  1.000 32.08543  ? 94  SER L HG   1 
ATOM   4659 N N    . GLU B 2 97  ? -9.53347  -14.60898 44.88875  1.000 21.98102  ? 95  GLU L N    1 
ATOM   4660 C CA   . GLU B 2 97  ? -8.69305  -15.69978 45.36836  1.000 24.21335  ? 95  GLU L CA   1 
ATOM   4661 C C    . GLU B 2 97  ? -8.63807  -16.87380 44.40140  1.000 21.44057  ? 95  GLU L C    1 
ATOM   4662 O O    . GLU B 2 97  ? -7.67900  -17.65479 44.44085  1.000 22.93910  ? 95  GLU L O    1 
ATOM   4663 C CB   . GLU B 2 97  ? -9.20022  -16.19962 46.72623  1.000 30.45434  ? 95  GLU L CB   1 
ATOM   4664 C CG   . GLU B 2 97  ? -9.01913  -15.21498 47.86576  1.000 42.39085  ? 95  GLU L CG   1 
ATOM   4665 C CD   . GLU B 2 97  ? -9.56200  -15.74203 49.18579  1.000 63.18782  ? 95  GLU L CD   1 
ATOM   4666 O OE1  . GLU B 2 97  ? -10.75467 -16.11563 49.23844  1.000 52.32400  ? 95  GLU L OE1  1 
ATOM   4667 O OE2  . GLU B 2 97  ? -8.79102  -15.79096 50.16939  1.000 66.11045  ? 95  GLU L OE2  1 
ATOM   4668 H H    . GLU B 2 97  ? -10.13658 -14.35611 45.44724  1.000 26.38406  ? 95  GLU L H    1 
ATOM   4669 H HA   . GLU B 2 97  ? -7.79316  -15.35459 45.47761  1.000 29.06285  ? 95  GLU L HA   1 
ATOM   4670 H HB2  . GLU B 2 97  ? -10.14843 -16.38972 46.65104  1.000 36.55204  ? 95  GLU L HB2  1 
ATOM   4671 H HB3  . GLU B 2 97  ? -8.71711  -17.00820 46.95798  1.000 36.55204  ? 95  GLU L HB3  1 
ATOM   4672 H HG2  . GLU B 2 97  ? -8.07311  -15.03400 47.98061  1.000 50.87585  ? 95  GLU L HG2  1 
ATOM   4673 H HG3  . GLU B 2 97  ? -9.49048  -14.39431 47.65311  1.000 50.87585  ? 95  GLU L HG3  1 
ATOM   4674 N N    . ASN B 2 98  A -9.65053  -17.03898 43.55353  1.000 19.52066  ? 95  ASN L N    1 
ATOM   4675 C CA   . ASN B 2 98  A -9.71787  -18.19556 42.66833  1.000 17.95845  ? 95  ASN L CA   1 
ATOM   4676 C C    . ASN B 2 98  A -9.88114  -17.79285 41.21126  1.000 20.45649  ? 95  ASN L C    1 
ATOM   4677 O O    . ASN B 2 98  A -10.28952 -18.62074 40.38784  1.000 19.66425  ? 95  ASN L O    1 
ATOM   4678 C CB   . ASN B 2 98  A -10.84734 -19.12763 43.10916  1.000 23.22765  ? 95  ASN L CB   1 
ATOM   4679 C CG   . ASN B 2 98  A -10.54307 -19.79279 44.42896  1.000 23.53887  ? 95  ASN L CG   1 
ATOM   4680 O OD1  . ASN B 2 98  A -9.68165  -20.67065 44.50246  1.000 22.30633  ? 95  ASN L OD1  1 
ATOM   4681 N ND2  . ASN B 2 98  A -11.21697 -19.35642 45.48809  1.000 21.14020  ? 95  ASN L ND2  1 
ATOM   4682 H H    . ASN B 2 98  A -10.31068 -16.49369 43.47314  1.000 23.43163  ? 95  ASN L H    1 
ATOM   4683 H HA   . ASN B 2 98  A -8.88444  -18.68841 42.72663  1.000 21.55697  ? 95  ASN L HA   1 
ATOM   4684 H HB2  . ASN B 2 98  A -11.66459 -18.61470 43.20869  1.000 27.88001  ? 95  ASN L HB2  1 
ATOM   4685 H HB3  . ASN B 2 98  A -10.96954 -19.82006 42.44095  1.000 27.88001  ? 95  ASN L HB3  1 
ATOM   4686 H HD21 . ASN B 2 98  A -11.07650 -19.70613 46.26112  1.000 25.37507  ? 95  ASN L HD21 1 
ATOM   4687 H HD22 . ASN B 2 98  A -11.79350 -18.72435 45.40042  1.000 25.37507  ? 95  ASN L HD22 1 
ATOM   4688 N N    . ASP B 2 99  B -9.54396  -16.55011 40.86853  1.000 18.45827  ? 95  ASP L N    1 
ATOM   4689 C CA   . ASP B 2 99  B -9.64018  -16.09645 39.48598  1.000 19.97661  ? 95  ASP L CA   1 
ATOM   4690 C C    . ASP B 2 99  B -8.62136  -14.98092 39.31987  1.000 21.44655  ? 95  ASP L C    1 
ATOM   4691 O O    . ASP B 2 99  B -8.49017  -14.13974 40.20701  1.000 22.48155  ? 95  ASP L O    1 
ATOM   4692 C CB   . ASP B 2 99  B -11.05910 -15.61582 39.17256  1.000 23.40100  ? 95  ASP L CB   1 
ATOM   4693 C CG   . ASP B 2 99  B -11.34048 -15.52573 37.68601  1.000 38.89700  ? 95  ASP L CG   1 
ATOM   4694 O OD1  . ASP B 2 99  B -10.65146 -16.20706 36.89510  1.000 35.86983  ? 95  ASP L OD1  1 
ATOM   4695 O OD2  . ASP B 2 99  B -12.26723 -14.76859 37.31444  1.000 38.67671  ? 95  ASP L OD2  1 
ATOM   4696 H H    . ASP B 2 99  B -9.25766  -15.95398 41.41832  1.000 22.15676  ? 95  ASP L H    1 
ATOM   4697 H HA   . ASP B 2 99  B -9.43228  -16.80357 38.85539  1.000 23.97876  ? 95  ASP L HA   1 
ATOM   4698 H HB2  . ASP B 2 99  B -11.69498 -16.23763 39.55974  1.000 28.08804  ? 95  ASP L HB2  1 
ATOM   4699 H HB3  . ASP B 2 99  B -11.18405 -14.73286 39.55422  1.000 28.08804  ? 95  ASP L HB3  1 
ATOM   4700 N N    . ALA B 2 100 C -7.88433  -14.98125 38.21159  1.000 20.77969  ? 95  ALA L N    1 
ATOM   4701 C CA   . ALA B 2 100 C -6.80575  -14.01213 38.05278  1.000 20.23573  ? 95  ALA L CA   1 
ATOM   4702 C C    . ALA B 2 100 C -6.68255  -13.58906 36.59466  1.000 22.80984  ? 95  ALA L C    1 
ATOM   4703 O O    . ALA B 2 100 C -6.72571  -14.42740 35.69286  1.000 22.05845  ? 95  ALA L O    1 
ATOM   4704 C CB   . ALA B 2 100 C -5.47595  -14.58671 38.55603  1.000 19.10388  ? 95  ALA L CB   1 
ATOM   4705 H H    . ALA B 2 100 C -7.98799  -15.52220 37.55112  1.000 24.94246  ? 95  ALA L H    1 
ATOM   4706 H HA   . ALA B 2 100 C -7.01882  -13.21482 38.56248  1.000 24.28971  ? 95  ALA L HA   1 
ATOM   4707 H HB1  . ALA B 2 100 C -4.77993  -13.92132 38.43888  1.000 22.93149  ? 95  ALA L HB1  1 
ATOM   4708 H HB2  . ALA B 2 100 C -5.56428  -14.81110 39.49558  1.000 22.93149  ? 95  ALA L HB2  1 
ATOM   4709 H HB3  . ALA B 2 100 C -5.26211  -15.38266 38.04454  1.000 22.93149  ? 95  ALA L HB3  1 
ATOM   4710 N N    . TYR B 2 101 D -6.51680  -12.28192 36.38082  1.000 18.84180  ? 95  TYR L N    1 
ATOM   4711 C CA   . TYR B 2 101 D -6.40825  -11.69221 35.05699  1.000 20.57937  ? 95  TYR L CA   1 
ATOM   4712 C C    . TYR B 2 101 D -5.36163  -10.58939 35.09738  1.000 13.77753  ? 95  TYR L C    1 
ATOM   4713 O O    . TYR B 2 101 D -5.12405  -9.97786  36.13975  1.000 13.33253  ? 95  TYR L O    1 
ATOM   4714 C CB   . TYR B 2 101 D -7.71379  -11.02771 34.55756  1.000 23.55851  ? 95  TYR L CB   1 
ATOM   4715 C CG   . TYR B 2 101 D -8.96645  -11.85335 34.64697  1.000 27.50824  ? 95  TYR L CG   1 
ATOM   4716 C CD1  . TYR B 2 101 D -9.68510  -11.92998 35.82818  1.000 25.63321  ? 95  TYR L CD1  1 
ATOM   4717 C CD2  . TYR B 2 101 D -9.45735  -12.52458 33.53095  1.000 41.27884  ? 95  TYR L CD2  1 
ATOM   4718 C CE1  . TYR B 2 101 D -10.85063 -12.67964 35.90826  1.000 38.38213  ? 95  TYR L CE1  1 
ATOM   4719 C CE2  . TYR B 2 101 D -10.61672 -13.27334 33.59718  1.000 41.30182  ? 95  TYR L CE2  1 
ATOM   4720 C CZ   . TYR B 2 101 D -11.31166 -13.34916 34.78615  1.000 40.88155  ? 95  TYR L CZ   1 
ATOM   4721 O OH   . TYR B 2 101 D -12.46513 -14.09730 34.84252  1.000 34.16527  ? 95  TYR L OH   1 
ATOM   4722 H H    . TYR B 2 101 D -6.46307  -11.70053 37.01225  1.000 22.61699  ? 95  TYR L H    1 
ATOM   4723 H HA   . TYR B 2 101 D -6.16233  -12.40496 34.44674  1.000 24.70208  ? 95  TYR L HA   1 
ATOM   4724 H HB2  . TYR B 2 101 D -7.86377  -10.22663 35.08357  1.000 28.27704  ? 95  TYR L HB2  1 
ATOM   4725 H HB3  . TYR B 2 101 D -7.59407  -10.79389 33.62381  1.000 28.27704  ? 95  TYR L HB3  1 
ATOM   4726 H HD1  . TYR B 2 101 D -9.38234  -11.47234 36.57905  1.000 30.76668  ? 95  TYR L HD1  1 
ATOM   4727 H HD2  . TYR B 2 101 D -8.99626  -12.46806 32.72529  1.000 49.54144  ? 95  TYR L HD2  1 
ATOM   4728 H HE1  . TYR B 2 101 D -11.31908 -12.73220 36.70994  1.000 46.06539  ? 95  TYR L HE1  1 
ATOM   4729 H HE2  . TYR B 2 101 D -10.92658 -13.72343 32.84465  1.000 49.56902  ? 95  TYR L HE2  1 
ATOM   4730 H HH   . TYR B 2 101 D -12.80147 -14.04927 35.61074  1.000 41.00516  ? 95  TYR L HH   1 
ATOM   4731 N N    . TYR B 2 102 ? -4.77517  -10.31386 33.94873  1.000 14.52080  ? 96  TYR L N    1 
ATOM   4732 C CA   . TYR B 2 102 ? -4.10558  -9.04730  33.71049  1.000 12.13512  ? 96  TYR L CA   1 
ATOM   4733 C C    . TYR B 2 102 ? -4.74078  -8.38558  32.49527  1.000 15.59103  ? 96  TYR L C    1 
ATOM   4734 O O    . TYR B 2 102 ? -5.25319  -9.06529  31.59795  1.000 17.20532  ? 96  TYR L O    1 
ATOM   4735 C CB   . TYR B 2 102 ? -2.61984  -9.21369  33.44757  1.000 15.79536  ? 96  TYR L CB   1 
ATOM   4736 C CG   . TYR B 2 102 ? -1.74007  -9.57993  34.63021  1.000 15.32929  ? 96  TYR L CG   1 
ATOM   4737 C CD1  . TYR B 2 102 ? -1.09421  -8.59933  35.37614  1.000 11.67749  ? 96  TYR L CD1  1 
ATOM   4738 C CD2  . TYR B 2 102 ? -1.49809  -10.90939 34.95002  1.000 12.95847  ? 96  TYR L CD2  1 
ATOM   4739 C CE1  . TYR B 2 102 ? -0.26216  -8.93268  36.43361  1.000 13.03051  ? 96  TYR L CE1  1 
ATOM   4740 C CE2  . TYR B 2 102 ? -0.66695  -11.25580 36.01037  1.000 14.72932  ? 96  TYR L CE2  1 
ATOM   4741 C CZ   . TYR B 2 102 ? -0.04816  -10.27102 36.74252  1.000 10.90556  ? 96  TYR L CZ   1 
ATOM   4742 O OH   . TYR B 2 102 ? 0.78754   -10.63730 37.77829  1.000 14.12385  ? 96  TYR L OH   1 
ATOM   4743 H H    . TYR B 2 102 ? -4.75031  -10.85293 33.27912  1.000 17.43179  ? 96  TYR L H    1 
ATOM   4744 H HA   . TYR B 2 102 ? -4.20479  -8.48420  34.49405  1.000 14.56898  ? 96  TYR L HA   1 
ATOM   4745 H HB2  . TYR B 2 102 ? -2.51074  -9.91659  32.78807  1.000 18.96126  ? 96  TYR L HB2  1 
ATOM   4746 H HB3  . TYR B 2 102 ? -2.28343  -8.37433  33.09658  1.000 18.96126  ? 96  TYR L HB3  1 
ATOM   4747 H HD1  . TYR B 2 102 ? -1.22300  -7.70366  35.16145  1.000 14.01982  ? 96  TYR L HD1  1 
ATOM   4748 H HD2  . TYR B 2 102 ? -1.89900  -11.58041 34.44613  1.000 15.55700  ? 96  TYR L HD2  1 
ATOM   4749 H HE1  . TYR B 2 102 ? 0.15018   -8.26532  36.93311  1.000 15.64344  ? 96  TYR L HE1  1 
ATOM   4750 H HE2  . TYR B 2 102 ? -0.53049  -12.15080 36.22309  1.000 17.68202  ? 96  TYR L HE2  1 
ATOM   4751 H HH   . TYR B 2 102 ? 1.16430   -9.95777  38.09748  1.000 16.95545  ? 96  TYR L HH   1 
ATOM   4752 N N    . ALA B 2 103 ? -4.68635  -7.06059  32.45595  1.000 12.19318  ? 97  ALA L N    1 
ATOM   4753 C CA   . ALA B 2 103 ? -5.16448  -6.32372  31.29345  1.000 13.76982  ? 97  ALA L CA   1 
ATOM   4754 C C    . ALA B 2 103 ? -4.19481  -5.19516  30.97971  1.000 15.07246  ? 97  ALA L C    1 
ATOM   4755 O O    . ALA B 2 103 ? -3.47616  -4.70720  31.85827  1.000 14.03762  ? 97  ALA L O    1 
ATOM   4756 C CB   . ALA B 2 103 ? -6.57830  -5.76151  31.50682  1.000 17.04309  ? 97  ALA L CB   1 
ATOM   4757 H H    . ALA B 2 103 ? -4.37754  -6.56664  33.08860  1.000 14.63865  ? 97  ALA L H    1 
ATOM   4758 H HA   . ALA B 2 103 ? -5.19533  -6.91912  30.52830  1.000 16.53061  ? 97  ALA L HA   1 
ATOM   4759 H HB1  . ALA B 2 103 ? -6.85269  -5.28519  30.70762  1.000 20.45854  ? 97  ALA L HB1  1 
ATOM   4760 H HB2  . ALA B 2 103 ? -7.18758  -6.49625  31.67957  1.000 20.45854  ? 97  ALA L HB2  1 
ATOM   4761 H HB3  . ALA B 2 103 ? -6.56647  -5.15642  32.26486  1.000 20.45854  ? 97  ALA L HB3  1 
ATOM   4762 N N    . PHE B 2 104 ? -4.18117  -4.79573  29.71114  1.000 13.54096  ? 98  PHE L N    1 
ATOM   4763 C CA   . PHE B 2 104 ? -3.32282  -3.73091  29.21372  1.000 15.89028  ? 98  PHE L CA   1 
ATOM   4764 C C    . PHE B 2 104 ? -4.16940  -2.61148  28.62370  1.000 16.15318  ? 98  PHE L C    1 
ATOM   4765 O O    . PHE B 2 104 ? -5.13575  -2.86868  27.89915  1.000 13.33636  ? 98  PHE L O    1 
ATOM   4766 C CB   . PHE B 2 104 ? -2.37559  -4.24225  28.12602  1.000 17.10793  ? 98  PHE L CB   1 
ATOM   4767 C CG   . PHE B 2 104 ? -1.36096  -5.23315  28.60913  1.000 16.50525  ? 98  PHE L CG   1 
ATOM   4768 C CD1  . PHE B 2 104 ? -1.68296  -6.57350  28.72295  1.000 15.45508  ? 98  PHE L CD1  1 
ATOM   4769 C CD2  . PHE B 2 104 ? -0.07557  -4.82605  28.92426  1.000 17.28786  ? 98  PHE L CD2  1 
ATOM   4770 C CE1  . PHE B 2 104 ? -0.74204  -7.48792  29.15112  1.000 17.96726  ? 98  PHE L CE1  1 
ATOM   4771 C CE2  . PHE B 2 104 ? 0.87389   -5.73653  29.35933  1.000 14.68030  ? 98  PHE L CE2  1 
ATOM   4772 C CZ   . PHE B 2 104 ? 0.53523   -7.06693  29.47709  1.000 18.24108  ? 98  PHE L CZ   1 
ATOM   4773 H H    . PHE B 2 104 ? -4.67879  -5.14018  29.10013  1.000 16.25599  ? 98  PHE L H    1 
ATOM   4774 H HA   . PHE B 2 104 ? -2.80254  -3.38100  29.95383  1.000 19.07517  ? 98  PHE L HA   1 
ATOM   4775 H HB2  . PHE B 2 104 ? -2.90170  -4.67369  27.43467  1.000 20.53635  ? 98  PHE L HB2  1 
ATOM   4776 H HB3  . PHE B 2 104 ? -1.89444  -3.48669  27.75383  1.000 20.53635  ? 98  PHE L HB3  1 
ATOM   4777 H HD1  . PHE B 2 104 ? -2.54112  -6.86109  28.50906  1.000 18.55292  ? 98  PHE L HD1  1 
ATOM   4778 H HD2  . PHE B 2 104 ? 0.15379   -3.92847  28.84271  1.000 20.75226  ? 98  PHE L HD2  1 
ATOM   4779 H HE1  . PHE B 2 104 ? -0.96660  -8.38772  29.22062  1.000 21.56754  ? 98  PHE L HE1  1 
ATOM   4780 H HE2  . PHE B 2 104 ? 1.73368   -5.45171  29.57039  1.000 17.62319  ? 98  PHE L HE2  1 
ATOM   4781 H HZ   . PHE B 2 104 ? 1.16536   -7.68226  29.77579  1.000 21.89613  ? 98  PHE L HZ   1 
ATOM   4782 N N    . GLY B 2 105 ? -3.79903  -1.37111  28.92211  1.000 12.51884  ? 99  GLY L N    1 
ATOM   4783 C CA   . GLY B 2 105 ? -4.28619  -0.26079  28.12927  1.000 15.03029  ? 99  GLY L CA   1 
ATOM   4784 C C    . GLY B 2 105 ? -3.87001  -0.38833  26.67714  1.000 17.63186  ? 99  GLY L C    1 
ATOM   4785 O O    . GLY B 2 105 ? -2.98160  -1.16401  26.31772  1.000 14.27224  ? 99  GLY L O    1 
ATOM   4786 H H    . GLY B 2 105 ? -3.27526  -1.15294  29.56837  1.000 15.02944  ? 99  GLY L H    1 
ATOM   4787 H HA2  . GLY B 2 105 ? -5.25483  -0.23219  28.17189  1.000 18.04319  ? 99  GLY L HA2  1 
ATOM   4788 H HA3  . GLY B 2 105 ? -3.92993  0.56996   28.48116  1.000 18.04319  ? 99  GLY L HA3  1 
ATOM   4789 N N    . GLN B 2 106 ? -4.53607  0.38532   25.81806  1.000 15.65982  ? 100 GLN L N    1 
ATOM   4790 C CA   . GLN B 2 106 ? -4.27794  0.24080   24.39310  1.000 17.35567  ? 100 GLN L CA   1 
ATOM   4791 C C    . GLN B 2 106 ? -2.93972  0.83652   23.98332  1.000 16.32191  ? 100 GLN L C    1 
ATOM   4792 O O    . GLN B 2 106 ? -2.47177  0.55701   22.87508  1.000 16.32329  ? 100 GLN L O    1 
ATOM   4793 C CB   . GLN B 2 106 ? -5.41842  0.86854   23.58077  1.000 21.29457  ? 100 GLN L CB   1 
ATOM   4794 C CG   . GLN B 2 106 ? -5.34932  2.37160   23.36960  1.000 18.83617  ? 100 GLN L CG   1 
ATOM   4795 C CD   . GLN B 2 106 ? -5.90208  3.17052   24.52450  1.000 15.88315  ? 100 GLN L CD   1 
ATOM   4796 O OE1  . GLN B 2 106 ? -6.17785  2.63995   25.60430  1.000 18.71277  ? 100 GLN L OE1  1 
ATOM   4797 N NE2  . GLN B 2 106 ? -6.08595  4.46094   24.29677  1.000 19.66714  ? 100 GLN L NE2  1 
ATOM   4798 H H    . GLN B 2 106 ? -5.12069  0.97889   26.03133  1.000 18.79862  ? 100 GLN L H    1 
ATOM   4799 H HA   . GLN B 2 106 ? -4.25750  -0.70312  24.17062  1.000 20.83364  ? 100 GLN L HA   1 
ATOM   4800 H HB2  . GLN B 2 106 ? -5.42460  0.45747   22.70220  1.000 25.56031  ? 100 GLN L HB2  1 
ATOM   4801 H HB3  . GLN B 2 106 ? -6.25278  0.68342   24.03954  1.000 25.56031  ? 100 GLN L HB3  1 
ATOM   4802 H HG2  . GLN B 2 106 ? -4.42168  2.62818   23.24896  1.000 22.61023  ? 100 GLN L HG2  1 
ATOM   4803 H HG3  . GLN B 2 106 ? -5.86233  2.60025   22.57875  1.000 22.61023  ? 100 GLN L HG3  1 
ATOM   4804 H HE21 . GLN B 2 106 ? -5.89274  4.79366   23.52763  1.000 23.60741  ? 100 GLN L HE21 1 
ATOM   4805 H HE22 . GLN B 2 106 ? -6.39867  4.96692   24.91789  1.000 23.60741  ? 100 GLN L HE22 1 
ATOM   4806 N N    . GLY B 2 107 ? -2.31571  1.63659   24.84853  1.000 16.32013  ? 101 GLY L N    1 
ATOM   4807 C CA   . GLY B 2 107 ? -1.04889  2.26007   24.54082  1.000 15.45818  ? 101 GLY L CA   1 
ATOM   4808 C C    . GLY B 2 107 ? -1.18568  3.72614   24.18824  1.000 13.81928  ? 101 GLY L C    1 
ATOM   4809 O O    . GLY B 2 107 ? -2.16954  4.13661   23.56242  1.000 15.93306  ? 101 GLY L O    1 
ATOM   4810 H H    . GLY B 2 107 ? -2.61695  1.83174   25.63004  1.000 19.59100  ? 101 GLY L H    1 
ATOM   4811 H HA2  . GLY B 2 107 ? -0.46169  2.18580   25.30931  1.000 18.55665  ? 101 GLY L HA2  1 
ATOM   4812 H HA3  . GLY B 2 107 ? -0.64285  1.80297   23.78777  1.000 18.55665  ? 101 GLY L HA3  1 
ATOM   4813 N N    . THR B 2 108 ? -0.20786  4.52610   24.59779  1.000 14.76059  ? 102 THR L N    1 
ATOM   4814 C CA   . THR B 2 108 ? -0.11351  5.94047   24.23473  1.000 13.39559  ? 102 THR L CA   1 
ATOM   4815 C C    . THR B 2 108 ? 1.24415   6.16439   23.59164  1.000 14.99380  ? 102 THR L C    1 
ATOM   4816 O O    . THR B 2 108 ? 2.27609   6.02205   24.25650  1.000 14.01830  ? 102 THR L O    1 
ATOM   4817 C CB   . THR B 2 108 ? -0.26732  6.84769   25.45090  1.000 16.47655  ? 102 THR L CB   1 
ATOM   4818 O OG1  . THR B 2 108 ? -1.55275  6.64832   26.03606  1.000 14.72332  ? 102 THR L OG1  1 
ATOM   4819 C CG2  . THR B 2 108 ? -0.09229  8.31947   25.04896  1.000 16.63597  ? 102 THR L CG2  1 
ATOM   4820 H H    . THR B 2 108 ? 0.43621   4.26556   25.10463  1.000 17.71954  ? 102 THR L H    1 
ATOM   4821 H HA   . THR B 2 108 ? -0.81806  6.15042   23.60194  1.000 16.08154  ? 102 THR L HA   1 
ATOM   4822 H HB   . THR B 2 108 ? 0.41408   6.63514   26.10773  1.000 19.77870  ? 102 THR L HB   1 
ATOM   4823 H HG1  . THR B 2 108 ? -2.15364  6.81700   25.47385  1.000 17.67482  ? 102 THR L HG1  1 
ATOM   4824 H HG21 . THR B 2 108 ? -0.41548  8.89760   25.75762  1.000 19.97000  ? 102 THR L HG21 1 
ATOM   4825 H HG22 . THR B 2 108 ? 0.84525   8.51064   24.88968  1.000 19.97000  ? 102 THR L HG22 1 
ATOM   4826 H HG23 . THR B 2 108 ? -0.59321  8.50402   24.23907  1.000 19.97000  ? 102 THR L HG23 1 
ATOM   4827 N N    . LYS B 2 109 ? 1.24536   6.50838   22.30966  1.000 12.46621  ? 103 LYS L N    1 
ATOM   4828 C CA   . LYS B 2 109 ? 2.48770   6.71954   21.58195  1.000 15.33667  ? 103 LYS L CA   1 
ATOM   4829 C C    . LYS B 2 109 ? 2.95248   8.14992   21.82181  1.000 17.56418  ? 103 LYS L C    1 
ATOM   4830 O O    . LYS B 2 109 ? 2.19538   9.09771   21.60225  1.000 17.99572  ? 103 LYS L O    1 
ATOM   4831 C CB   . LYS B 2 109 ? 2.28671   6.44573   20.09391  1.000 21.70087  ? 103 LYS L CB   1 
ATOM   4832 C CG   . LYS B 2 109 ? 3.57318   6.42414   19.26921  1.000 31.77941  ? 103 LYS L CG   1 
ATOM   4833 C CD   . LYS B 2 109 ? 3.26206   6.24733   17.77958  1.000 50.91016  ? 103 LYS L CD   1 
ATOM   4834 C CE   . LYS B 2 109 ? 4.51256   5.97588   16.95108  1.000 56.41475  ? 103 LYS L CE   1 
ATOM   4835 N NZ   . LYS B 2 109 ? 5.49388   7.09599   17.00487  1.000 67.03540  ? 103 LYS L NZ   1 
ATOM   4836 H H    . LYS B 2 109 ? 0.53632   6.62602   21.83741  1.000 14.96629  ? 103 LYS L H    1 
ATOM   4837 H HA   . LYS B 2 109 ? 3.17141   6.11027   21.90169  1.000 18.41084  ? 103 LYS L HA   1 
ATOM   4838 H HB2  . LYS B 2 109 ? 1.86150   5.57956   19.99464  1.000 26.04788  ? 103 LYS L HB2  1 
ATOM   4839 H HB3  . LYS B 2 109 ? 1.71626   7.13931   19.72726  1.000 26.04788  ? 103 LYS L HB3  1 
ATOM   4840 H HG2  . LYS B 2 109 ? 4.04763   7.26193   19.38716  1.000 38.14213  ? 103 LYS L HG2  1 
ATOM   4841 H HG3  . LYS B 2 109 ? 4.13016   5.68405   19.55721  1.000 38.14213  ? 103 LYS L HG3  1 
ATOM   4842 H HD2  . LYS B 2 109 ? 2.65864   5.49608   17.66820  1.000 61.09903  ? 103 LYS L HD2  1 
ATOM   4843 H HD3  . LYS B 2 109 ? 2.84854   7.05772   17.44318  1.000 61.09903  ? 103 LYS L HD3  1 
ATOM   4844 H HE2  . LYS B 2 109 ? 4.94913   5.17842   17.28925  1.000 67.70453  ? 103 LYS L HE2  1 
ATOM   4845 H HE3  . LYS B 2 109 ? 4.25621   5.84620   16.02460  1.000 67.70453  ? 103 LYS L HE3  1 
ATOM   4846 H HZ1  . LYS B 2 109 ? 5.75810   7.22916   17.84424  1.000 80.44931  ? 103 LYS L HZ1  1 
ATOM   4847 H HZ2  . LYS B 2 109 ? 6.20470   6.90218   16.50561  1.000 80.44931  ? 103 LYS L HZ2  1 
ATOM   4848 H HZ3  . LYS B 2 109 ? 5.12020   7.84307   16.69771  1.000 80.44931  ? 103 LYS L HZ3  1 
ATOM   4849 N N    . VAL B 2 110 ? 4.17809   8.30066   22.31081  1.000 15.14474  ? 104 VAL L N    1 
ATOM   4850 C CA   . VAL B 2 110 ? 4.77961   9.59533   22.60105  1.000 15.37959  ? 104 VAL L CA   1 
ATOM   4851 C C    . VAL B 2 110 ? 5.90116   9.81502   21.59435  1.000 17.37294  ? 104 VAL L C    1 
ATOM   4852 O O    . VAL B 2 110 ? 6.86742   9.03412   21.54558  1.000 17.08729  ? 104 VAL L O    1 
ATOM   4853 C CB   . VAL B 2 110 ? 5.29899   9.66574   24.04412  1.000 14.67998  ? 104 VAL L CB   1 
ATOM   4854 C CG1  . VAL B 2 110 ? 6.09674   10.95631  24.28216  1.000 15.76038  ? 104 VAL L CG1  1 
ATOM   4855 C CG2  . VAL B 2 110 ? 4.13682   9.55739   25.02501  1.000 15.58264  ? 104 VAL L CG2  1 
ATOM   4856 H H    . VAL B 2 110 ? 4.70032   7.64112   22.48938  1.000 18.18053  ? 104 VAL L H    1 
ATOM   4857 H HA   . VAL B 2 110 ? 4.12060   10.29748  22.48448  1.000 18.46234  ? 104 VAL L HA   1 
ATOM   4858 H HB   . VAL B 2 110 ? 5.90050   8.92021   24.19669  1.000 17.62280  ? 104 VAL L HB   1 
ATOM   4859 H HG11 . VAL B 2 110 ? 6.22795   11.07509  25.23587  1.000 18.91930  ? 104 VAL L HG11 1 
ATOM   4860 H HG12 . VAL B 2 110 ? 6.95531   10.88356  23.83667  1.000 18.91930  ? 104 VAL L HG12 1 
ATOM   4861 H HG13 . VAL B 2 110 ? 5.59907   11.70639  23.92078  1.000 18.91930  ? 104 VAL L HG13 1 
ATOM   4862 H HG21 . VAL B 2 110 ? 4.48072   9.61775   25.92999  1.000 18.70601  ? 104 VAL L HG21 1 
ATOM   4863 H HG22 . VAL B 2 110 ? 3.51446   10.28257  24.85860  1.000 18.70601  ? 104 VAL L HG22 1 
ATOM   4864 H HG23 . VAL B 2 110 ? 3.69311   8.70453   24.89596  1.000 18.70601  ? 104 VAL L HG23 1 
ATOM   4865 N N    . GLU B 2 111 ? 5.74351   10.86468  20.78179  1.000 16.51258  ? 105 GLU L N    1 
ATOM   4866 C CA   . GLU B 2 111 ? 6.71983   11.33320  19.81139  1.000 21.55160  ? 105 GLU L CA   1 
ATOM   4867 C C    . GLU B 2 111 ? 7.29736   12.66655  20.27599  1.000 20.45658  ? 105 GLU L C    1 
ATOM   4868 O O    . GLU B 2 111 ? 6.61120   13.46644  20.92011  1.000 20.48808  ? 105 GLU L O    1 
ATOM   4869 C CB   . GLU B 2 111 ? 6.09091   11.52351  18.42814  1.000 26.34384  ? 105 GLU L CB   1 
ATOM   4870 C CG   . GLU B 2 111 ? 5.48062   10.27351  17.81464  1.000 47.74660  ? 105 GLU L CG   1 
ATOM   4871 C CD   . GLU B 2 111 ? 4.76634   10.56472  16.50146  1.000 63.80206  ? 105 GLU L CD   1 
ATOM   4872 O OE1  . GLU B 2 111 ? 4.57878   11.75882  16.17625  1.000 55.56985  ? 105 GLU L OE1  1 
ATOM   4873 O OE2  . GLU B 2 111 ? 4.39357   9.60220   15.79503  1.000 68.01784  ? 105 GLU L OE2  1 
ATOM   4874 H H    . GLU B 2 111 ? 5.03196   11.34767  20.77893  1.000 19.82193  ? 105 GLU L H    1 
ATOM   4875 H HA   . GLU B 2 111 ? 7.43258   10.67974  19.73463  1.000 25.86876  ? 105 GLU L HA   1 
ATOM   4876 H HB2  . GLU B 2 111 ? 5.38474   12.18445  18.50156  1.000 31.61944  ? 105 GLU L HB2  1 
ATOM   4877 H HB3  . GLU B 2 111 ? 6.77819   11.83845  17.82039  1.000 31.61944  ? 105 GLU L HB3  1 
ATOM   4878 H HG2  . GLU B 2 111 ? 6.18430   9.62931   17.63927  1.000 57.30276  ? 105 GLU L HG2  1 
ATOM   4879 H HG3  . GLU B 2 111 ? 4.83434   9.89869   18.43329  1.000 57.30276  ? 105 GLU L HG3  1 
ATOM   4880 N N    . ILE B 2 112 ? 8.55679   12.90823  19.92474  1.000 14.44971  ? 106 ILE L N    1 
ATOM   4881 C CA   . ILE B 2 112 ? 9.28993   14.08969  20.36577  1.000 17.86905  ? 106 ILE L CA   1 
ATOM   4882 C C    . ILE B 2 112 ? 9.28432   15.13518  19.26034  1.000 23.66766  ? 106 ILE L C    1 
ATOM   4883 O O    . ILE B 2 112 ? 9.66392   14.84716  18.11767  1.000 19.06224  ? 106 ILE L O    1 
ATOM   4884 C CB   . ILE B 2 112 ? 10.73684  13.73953  20.75430  1.000 20.16180  ? 106 ILE L CB   1 
ATOM   4885 C CG1  . ILE B 2 112 ? 10.77814  12.59584  21.76751  1.000 21.67665  ? 106 ILE L CG1  1 
ATOM   4886 C CG2  . ILE B 2 112 ? 11.44682  14.98429  21.29173  1.000 22.47683  ? 106 ILE L CG2  1 
ATOM   4887 C CD1  . ILE B 2 112 ? 10.12890  12.91052  23.09530  1.000 25.35895  ? 106 ILE L CD1  1 
ATOM   4888 H H    . ILE B 2 112 ? 9.01897   12.38875  19.41865  1.000 17.34649  ? 106 ILE L H    1 
ATOM   4889 H HA   . ILE B 2 112 ? 8.83269   14.45850  21.13766  1.000 21.44969  ? 106 ILE L HA   1 
ATOM   4890 H HB   . ILE B 2 112 ? 11.20220  13.43418  19.95988  1.000 24.20100  ? 106 ILE L HB   1 
ATOM   4891 H HG12 . ILE B 2 112 ? 10.31596  11.83139  21.38948  1.000 26.01882  ? 106 ILE L HG12 1 
ATOM   4892 H HG13 . ILE B 2 112 ? 11.70543  12.37031  21.94115  1.000 26.01882  ? 106 ILE L HG13 1 
ATOM   4893 H HG21 . ILE B 2 112 ? 12.27535  14.71567  21.71867  1.000 26.97903  ? 106 ILE L HG21 1 
ATOM   4894 H HG22 . ILE B 2 112 ? 11.63471  15.58431  20.55310  1.000 26.97903  ? 106 ILE L HG22 1 
ATOM   4895 H HG23 . ILE B 2 112 ? 10.86989  15.42343  21.93610  1.000 26.97903  ? 106 ILE L HG23 1 
ATOM   4896 H HD11 . ILE B 2 112 ? 10.20195  12.13555  23.67408  1.000 30.43757  ? 106 ILE L HD11 1 
ATOM   4897 H HD12 . ILE B 2 112 ? 10.58295  13.66757  23.49730  1.000 30.43757  ? 106 ILE L HD12 1 
ATOM   4898 H HD13 . ILE B 2 112 ? 9.19478   13.12571  22.94696  1.000 30.43757  ? 106 ILE L HD13 1 
ATOM   4899 N N    . LYS B 2 113 ? 8.89494   16.35750  19.61277  1.000 19.16000  ? 107 LYS L N    1 
ATOM   4900 C CA   . LYS B 2 113 ? 8.94910   17.49334  18.70598  1.000 20.66558  ? 107 LYS L CA   1 
ATOM   4901 C C    . LYS B 2 113 ? 10.28951  18.20594  18.81637  1.000 21.31032  ? 107 LYS L C    1 
ATOM   4902 O O    . LYS B 2 113 ? 10.86097  18.32394  19.90302  1.000 22.15011  ? 107 LYS L O    1 
ATOM   4903 C CB   . LYS B 2 113 ? 7.82627   18.48104  19.01366  1.000 25.54555  ? 107 LYS L CB   1 
ATOM   4904 C CG   . LYS B 2 113 ? 6.50852   18.14863  18.35547  1.000 29.98162  ? 107 LYS L CG   1 
ATOM   4905 C CD   . LYS B 2 113 ? 5.31851   18.65883  19.17135  1.000 41.10953  ? 107 LYS L CD   1 
ATOM   4906 C CE   . LYS B 2 113 ? 5.37637   20.16075  19.43659  1.000 46.61992  ? 107 LYS L CE   1 
ATOM   4907 N NZ   . LYS B 2 113 ? 4.70436   20.49991  20.72664  1.000 52.37839  ? 107 LYS L NZ   1 
ATOM   4908 H H    . LYS B 2 113 ? 8.58849   16.55656  20.39128  1.000 22.99883  ? 107 LYS L H    1 
ATOM   4909 H HA   . LYS B 2 113 ? 8.84453   17.17346  17.79623  1.000 24.80552  ? 107 LYS L HA   1 
ATOM   4910 H HB2  . LYS B 2 113 ? 7.68044   18.49524  19.97253  1.000 30.66150  ? 107 LYS L HB2  1 
ATOM   4911 H HB3  . LYS B 2 113 ? 8.09477   19.36084  18.70585  1.000 30.66150  ? 107 LYS L HB3  1 
ATOM   4912 H HG2  . LYS B 2 113 ? 6.47525   18.56302  17.47907  1.000 35.98477  ? 107 LYS L HG2  1 
ATOM   4913 H HG3  . LYS B 2 113 ? 6.42737   17.18577  18.27047  1.000 35.98477  ? 107 LYS L HG3  1 
ATOM   4914 H HD2  . LYS B 2 113 ? 4.49991   18.47302  18.68527  1.000 49.33828  ? 107 LYS L HD2  1 
ATOM   4915 H HD3  . LYS B 2 113 ? 5.30578   18.20477  20.02842  1.000 49.33828  ? 107 LYS L HD3  1 
ATOM   4916 H HE2  . LYS B 2 113 ? 6.30246   20.44467  19.48821  1.000 55.95074  ? 107 LYS L HE2  1 
ATOM   4917 H HE3  . LYS B 2 113 ? 4.92390   20.63336  18.72048  1.000 55.95074  ? 107 LYS L HE3  1 
ATOM   4918 H HZ1  . LYS B 2 113 ? 4.75181   21.37645  20.87334  1.000 62.86090  ? 107 LYS L HZ1  1 
ATOM   4919 H HZ2  . LYS B 2 113 ? 3.84840   20.25797  20.69679  1.000 62.86090  ? 107 LYS L HZ2  1 
ATOM   4920 H HZ3  . LYS B 2 113 ? 5.10201   20.07266  21.39853  1.000 62.86090  ? 107 LYS L HZ3  1 
ATOM   4921 N N    . ARG B 2 114 ? 10.77588  18.69931  17.68496  1.000 20.44527  ? 108 ARG L N    1 
ATOM   4922 C CA   . ARG B 2 114 ? 12.03376  19.42702  17.64210  1.000 21.06635  ? 108 ARG L CA   1 
ATOM   4923 C C    . ARG B 2 114 ? 12.01450  20.33823  16.42003  1.000 22.94872  ? 108 ARG L C    1 
ATOM   4924 O O    . ARG B 2 114 ? 11.04928  20.36025  15.64919  1.000 23.33996  ? 108 ARG L O    1 
ATOM   4925 C CB   . ARG B 2 114 ? 13.22106  18.46371  17.61801  1.000 20.74760  ? 108 ARG L CB   1 
ATOM   4926 C CG   . ARG B 2 114 ? 13.21953  17.49490  16.43449  1.000 19.71209  ? 108 ARG L CG   1 
ATOM   4927 C CD   . ARG B 2 114 ? 14.63498  17.14109  16.02839  1.000 23.84644  ? 108 ARG L CD   1 
ATOM   4928 N NE   . ARG B 2 114 ? 15.34407  18.29284  15.48312  1.000 24.18632  ? 108 ARG L NE   1 
ATOM   4929 C CZ   . ARG B 2 114 ? 16.66393  18.38644  15.38412  1.000 21.89721  ? 108 ARG L CZ   1 
ATOM   4930 N NH1  . ARG B 2 114 ? 17.46021  17.41148  15.78843  1.000 23.64184  ? 108 ARG L NH1  1 
ATOM   4931 N NH2  . ARG B 2 114 ? 17.19880  19.49137  14.87545  1.000 25.92692  ? 108 ARG L NH2  1 
ATOM   4932 H H    . ARG B 2 114 ? 10.39025  18.62419  16.91994  1.000 24.54115  ? 108 ARG L H    1 
ATOM   4933 H HA   . ARG B 2 114 ? 12.11121  19.98421  18.43231  1.000 25.28645  ? 108 ARG L HA   1 
ATOM   4934 H HB2  . ARG B 2 114 ? 14.03978  18.98194  17.57282  1.000 24.90396  ? 108 ARG L HB2  1 
ATOM   4935 H HB3  . ARG B 2 114 ? 13.20763  17.93484  18.43104  1.000 24.90396  ? 108 ARG L HB3  1 
ATOM   4936 H HG2  . ARG B 2 114 ? 12.75773  16.67918  16.68398  1.000 23.66134  ? 108 ARG L HG2  1 
ATOM   4937 H HG3  . ARG B 2 114 ? 12.77630  17.90878  15.67742  1.000 23.66134  ? 108 ARG L HG3  1 
ATOM   4938 H HD2  . ARG B 2 114 ? 15.12145  16.82450  16.80558  1.000 28.62256  ? 108 ARG L HD2  1 
ATOM   4939 H HD3  . ARG B 2 114 ? 14.60972  16.44971  15.34849  1.000 28.62256  ? 108 ARG L HD3  1 
ATOM   4940 H HE   . ARG B 2 114 ? 14.87401  18.95774  15.20644  1.000 29.03042  ? 108 ARG L HE   1 
ATOM   4941 H HH11 . ARG B 2 114 ? 17.12534  16.69460  16.12539  1.000 28.37704  ? 108 ARG L HH11 1 
ATOM   4942 H HH12 . ARG B 2 114 ? 18.31302  17.49420  15.71446  1.000 28.37704  ? 108 ARG L HH12 1 
ATOM   4943 H HH21 . ARG B 2 114 ? 16.69076  20.13464  14.61526  1.000 31.11914  ? 108 ARG L HH21 1 
ATOM   4944 H HH22 . ARG B 2 114 ? 18.05301  19.56321  14.80643  1.000 31.11914  ? 108 ARG L HH22 1 
ATOM   4945 N N    . THR B 2 115 ? 13.09438  21.09274  16.24977  1.000 22.36421  ? 109 THR L N    1 
ATOM   4946 C CA   . THR B 2 115 ? 13.19743  22.00488  15.12168  1.000 24.18838  ? 109 THR L CA   1 
ATOM   4947 C C    . THR B 2 115 ? 13.47736  21.22178  13.84347  1.000 24.22524  ? 109 THR L C    1 
ATOM   4948 O O    . THR B 2 115 ? 13.96452  20.08706  13.87056  1.000 21.38916  ? 109 THR L O    1 
ATOM   4949 C CB   . THR B 2 115 ? 14.30119  23.03716  15.36288  1.000 29.32712  ? 109 THR L CB   1 
ATOM   4950 O OG1  . THR B 2 115 ? 15.56758  22.37615  15.42759  1.000 26.14799  ? 109 THR L OG1  1 
ATOM   4951 C CG2  . THR B 2 115 ? 14.05453  23.78432  16.66649  1.000 33.48006  ? 109 THR L CG2  1 
ATOM   4952 H H    . THR B 2 115 ? 13.77779  21.09432  16.77183  1.000 26.84388  ? 109 THR L H    1 
ATOM   4953 H HA   . THR B 2 115 ? 12.36293  22.48686  15.01122  1.000 29.03289  ? 109 THR L HA   1 
ATOM   4954 H HB   . THR B 2 115 ? 14.30907  23.68082  14.63725  1.000 35.19938  ? 109 THR L HB   1 
ATOM   4955 H HG1  . THR B 2 115 ? 16.17785  22.93712  15.56353  1.000 31.38442  ? 109 THR L HG1  1 
ATOM   4956 H HG21 . THR B 2 115 ? 14.70659  24.49495  16.77008  1.000 40.18291  ? 109 THR L HG21 1 
ATOM   4957 H HG22 . THR B 2 115 ? 13.16502  24.17119  16.66396  1.000 40.18291  ? 109 THR L HG22 1 
ATOM   4958 H HG23 . THR B 2 115 ? 14.13075  23.17520  17.41754  1.000 40.18291  ? 109 THR L HG23 1 
ATOM   4959 N N    . VAL B 2 116 ? 13.14149  21.83696  12.70768  1.000 24.28872  ? 110 VAL L N    1 
ATOM   4960 C CA   . VAL B 2 116 ? 13.31707  21.15692  11.43385  1.000 25.08385  ? 110 VAL L CA   1 
ATOM   4961 C C    . VAL B 2 116 ? 14.79916  20.90418  11.18943  1.000 23.01963  ? 110 VAL L C    1 
ATOM   4962 O O    . VAL B 2 116 ? 15.66465  21.69725  11.57805  1.000 23.01774  ? 110 VAL L O    1 
ATOM   4963 C CB   . VAL B 2 116 ? 12.69254  21.95553  10.27574  1.000 27.67943  ? 110 VAL L CB   1 
ATOM   4964 C CG1  . VAL B 2 116 ? 11.17377  21.98843  10.40921  1.000 30.57003  ? 110 VAL L CG1  1 
ATOM   4965 C CG2  . VAL B 2 116 ? 13.24205  23.36943  10.21244  1.000 37.15942  ? 110 VAL L CG2  1 
ATOM   4966 H H    . VAL B 2 116 ? 12.81695  22.63146  12.65245  1.000 29.15329  ? 110 VAL L H    1 
ATOM   4967 H HA   . VAL B 2 116 ? 12.86125  20.30169  11.47511  1.000 30.10746  ? 110 VAL L HA   1 
ATOM   4968 H HB   . VAL B 2 116 ? 12.92546  21.51084  9.44574   1.000 33.22215  ? 110 VAL L HB   1 
ATOM   4969 H HG11 . VAL B 2 116 ? 10.78273  22.13024  9.53292   1.000 36.69087  ? 110 VAL L HG11 1 
ATOM   4970 H HG12 . VAL B 2 116 ? 10.87039  21.14231  10.77382  1.000 36.69087  ? 110 VAL L HG12 1 
ATOM   4971 H HG13 . VAL B 2 116 ? 10.92463  22.71319  11.00382  1.000 36.69087  ? 110 VAL L HG13 1 
ATOM   4972 H HG21 . VAL B 2 116 ? 12.67612  23.90252  9.63242   1.000 44.59814  ? 110 VAL L HG21 1 
ATOM   4973 H HG22 . VAL B 2 116 ? 13.24793  23.74626  11.10623  1.000 44.59814  ? 110 VAL L HG22 1 
ATOM   4974 H HG23 . VAL B 2 116 ? 14.14501  23.34178  9.85918   1.000 44.59814  ? 110 VAL L HG23 1 
ATOM   4975 N N    . ALA B 2 117 ? 15.09219  19.77037  10.55349  1.000 24.09805  ? 111 ALA L N    1 
ATOM   4976 C CA   . ALA B 2 117 ? 16.45538  19.39112  10.21103  1.000 16.38687  ? 111 ALA L CA   1 
ATOM   4977 C C    . ALA B 2 117 ? 16.44518  18.82322  8.80225   1.000 22.99096  ? 111 ALA L C    1 
ATOM   4978 O O    . ALA B 2 117 ? 15.67528  17.90483  8.50473   1.000 19.31761  ? 111 ALA L O    1 
ATOM   4979 C CB   . ALA B 2 117 ? 17.02183  18.36612  11.20085  1.000 24.04380  ? 111 ALA L CB   1 
ATOM   4980 H H    . ALA B 2 117 ? 14.50377  19.19413  10.30589  1.000 28.92449  ? 111 ALA L H    1 
ATOM   4981 H HA   . ALA B 2 117 ? 17.03396  20.16935  10.23364  1.000 19.67108  ? 111 ALA L HA   1 
ATOM   4982 H HB1  . ALA B 2 117 ? 17.93062  18.14645  10.94251  1.000 28.85939  ? 111 ALA L HB1  1 
ATOM   4983 H HB2  . ALA B 2 117 ? 17.01477  18.74999  12.09163  1.000 28.85939  ? 111 ALA L HB2  1 
ATOM   4984 H HB3  . ALA B 2 117 ? 16.47006  17.56861  11.17996  1.000 28.85939  ? 111 ALA L HB3  1 
ATOM   4985 N N    . ALA B 2 118 ? 17.28070  19.37754  7.94395   1.000 19.86109  ? 112 ALA L N    1 
ATOM   4986 C CA   . ALA B 2 118 ? 17.28759  18.94841  6.55453   1.000 24.40019  ? 112 ALA L CA   1 
ATOM   4987 C C    . ALA B 2 118 ? 18.00735  17.60659  6.42189   1.000 21.26978  ? 112 ALA L C    1 
ATOM   4988 O O    . ALA B 2 118 ? 19.00807  17.36815  7.09684   1.000 18.36134  ? 112 ALA L O    1 
ATOM   4989 C CB   . ALA B 2 118 ? 17.96982  19.99385  5.67654   1.000 23.30761  ? 112 ALA L CB   1 
ATOM   4990 H H    . ALA B 2 118 ? 17.84716  19.99583  8.13485   1.000 23.84015  ? 112 ALA L H    1 
ATOM   4991 H HA   . ALA B 2 118 ? 16.37608  18.83798  6.24173   1.000 29.28707  ? 112 ALA L HA   1 
ATOM   4992 H HB1  . ALA B 2 118 ? 17.96192  19.68721  4.75632   1.000 27.97596  ? 112 ALA L HB1  1 
ATOM   4993 H HB2  . ALA B 2 118 ? 17.48684  20.83184  5.75011   1.000 27.97596  ? 112 ALA L HB2  1 
ATOM   4994 H HB3  . ALA B 2 118 ? 18.88419  20.11149  5.97817   1.000 27.97596  ? 112 ALA L HB3  1 
ATOM   4995 N N    . PRO B 2 119 ? 17.52245  16.72191  5.55705   1.000 20.12803  ? 113 PRO L N    1 
ATOM   4996 C CA   . PRO B 2 119 ? 18.17767  15.42253  5.38438   1.000 22.27771  ? 113 PRO L CA   1 
ATOM   4997 C C    . PRO B 2 119 ? 19.48113  15.52934  4.60982   1.000 24.24159  ? 113 PRO L C    1 
ATOM   4998 O O    . PRO B 2 119 ? 19.65774  16.40908  3.76305   1.000 22.66426  ? 113 PRO L O    1 
ATOM   4999 C CB   . PRO B 2 119 ? 17.13974  14.62183  4.59143   1.000 20.89902  ? 113 PRO L CB   1 
ATOM   5000 C CG   . PRO B 2 119 ? 16.42973  15.64156  3.80960   1.000 24.03143  ? 113 PRO L CG   1 
ATOM   5001 C CD   . PRO B 2 119 ? 16.34725  16.86107  4.68162   1.000 20.52441  ? 113 PRO L CD   1 
ATOM   5002 H HA   . PRO B 2 119 ? 18.34840  15.00925  6.24517   1.000 26.74009  ? 113 PRO L HA   1 
ATOM   5003 H HB2  . PRO B 2 119 ? 17.58211  13.98094  4.01309   1.000 25.08565  ? 113 PRO L HB2  1 
ATOM   5004 H HB3  . PRO B 2 119 ? 16.53789  14.16181  5.19728   1.000 25.08565  ? 113 PRO L HB3  1 
ATOM   5005 H HG2  . PRO B 2 119 ? 16.92651  15.83406  2.99901   1.000 28.84455  ? 113 PRO L HG2  1 
ATOM   5006 H HG3  . PRO B 2 119 ? 15.54208  15.32044  3.58634   1.000 28.84455  ? 113 PRO L HG3  1 
ATOM   5007 H HD2  . PRO B 2 119 ? 16.40464  17.67095  4.15087   1.000 24.63612  ? 113 PRO L HD2  1 
ATOM   5008 H HD3  . PRO B 2 119 ? 15.52733  16.86147  5.19992   1.000 24.63612  ? 113 PRO L HD3  1 
ATOM   5009 N N    . SER B 2 120 ? 20.40047  14.60964  4.89939   1.000 20.02145  ? 114 SER L N    1 
ATOM   5010 C CA   . SER B 2 120 ? 21.52949  14.34733  4.00749   1.000 21.09274  ? 114 SER L CA   1 
ATOM   5011 C C    . SER B 2 120 ? 21.10423  13.25193  3.03093   1.000 19.96851  ? 114 SER L C    1 
ATOM   5012 O O    . SER B 2 120 ? 20.69601  12.17261  3.45515   1.000 20.08616  ? 114 SER L O    1 
ATOM   5013 C CB   . SER B 2 120 ? 22.76882  13.91829  4.79010   1.000 26.97339  ? 114 SER L CB   1 
ATOM   5014 O OG   . SER B 2 120 ? 23.14204  14.90134  5.73624   1.000 40.51721  ? 114 SER L OG   1 
ATOM   5015 H H    . SER B 2 120 ? 20.39230  14.12312  5.60850   1.000 24.03258  ? 114 SER L H    1 
ATOM   5016 H HA   . SER B 2 120 ? 21.76076  15.15273  3.51888   1.000 25.31812  ? 114 SER L HA   1 
ATOM   5017 H HB2  . SER B 2 120 ? 22.57481  13.09041  5.25688   1.000 32.37490  ? 114 SER L HB2  1 
ATOM   5018 H HB3  . SER B 2 120 ? 23.50211  13.78512  4.16927   1.000 32.37490  ? 114 SER L HB3  1 
ATOM   5019 H HG   . SER B 2 120 ? 22.51863  15.02220  6.28610   1.000 48.62749  ? 114 SER L HG   1 
ATOM   5020 N N    . VAL B 2 121 ? 21.17289  13.52157  1.73417   1.000 18.81594  ? 115 VAL L N    1 
ATOM   5021 C CA   . VAL B 2 121 ? 20.58918  12.63325  0.73624   1.000 17.54944  ? 115 VAL L CA   1 
ATOM   5022 C C    . VAL B 2 121 ? 21.69380  11.88527  -0.00038  1.000 19.92969  ? 115 VAL L C    1 
ATOM   5023 O O    . VAL B 2 121 ? 22.64575  12.49687  -0.49847  1.000 19.76100  ? 115 VAL L O    1 
ATOM   5024 C CB   . VAL B 2 121 ? 19.70120  13.41051  -0.24951  1.000 15.04629  ? 115 VAL L CB   1 
ATOM   5025 C CG1  . VAL B 2 121 ? 19.00125  12.44810  -1.17952  1.000 19.54345  ? 115 VAL L CG1  1 
ATOM   5026 C CG2  . VAL B 2 121 ? 18.69464  14.26110  0.50065   1.000 20.32903  ? 115 VAL L CG2  1 
ATOM   5027 H H    . VAL B 2 121 ? 21.55523  14.21817  1.40528   1.000 22.58596  ? 115 VAL L H    1 
ATOM   5028 H HA   . VAL B 2 121 ? 20.04918  11.97062  1.19474   1.000 21.06616  ? 115 VAL L HA   1 
ATOM   5029 H HB   . VAL B 2 121 ? 20.25455  14.00385  -0.78116  1.000 18.06238  ? 115 VAL L HB   1 
ATOM   5030 H HG11 . VAL B 2 121 ? 18.34339  12.93450  -1.70061  1.000 23.45897  ? 115 VAL L HG11 1 
ATOM   5031 H HG12 . VAL B 2 121 ? 19.65759  12.04473  -1.76893  1.000 23.45897  ? 115 VAL L HG12 1 
ATOM   5032 H HG13 . VAL B 2 121 ? 18.56370  11.76136  -0.65241  1.000 23.45897  ? 115 VAL L HG13 1 
ATOM   5033 H HG21 . VAL B 2 121 ? 18.07388  14.65018  -0.13509  1.000 24.40167  ? 115 VAL L HG21 1 
ATOM   5034 H HG22 . VAL B 2 121 ? 18.21505  13.70086  1.13075   1.000 24.40167  ? 115 VAL L HG22 1 
ATOM   5035 H HG23 . VAL B 2 121 ? 19.16611  14.96368  0.97498   1.000 24.40167  ? 115 VAL L HG23 1 
ATOM   5036 N N    . PHE B 2 122 ? 21.54464  10.56446  -0.09481  1.000 15.77946  ? 116 PHE L N    1 
ATOM   5037 C CA   . PHE B 2 122 ? 22.46040  9.70982   -0.84017  1.000 16.18504  ? 116 PHE L CA   1 
ATOM   5038 C C    . PHE B 2 122 ? 21.67051  8.81692   -1.78528  1.000 18.89744  ? 116 PHE L C    1 
ATOM   5039 O O    . PHE B 2 122 ? 20.56703  8.38137   -1.46319  1.000 19.44233  ? 116 PHE L O    1 
ATOM   5040 C CB   . PHE B 2 122 ? 23.29494  8.82149   0.09027   1.000 20.14675  ? 116 PHE L CB   1 
ATOM   5041 C CG   . PHE B 2 122 ? 24.04884  9.57419   1.13831   1.000 18.62152  ? 116 PHE L CG   1 
ATOM   5042 C CD1  . PHE B 2 122 ? 23.43298  9.94128   2.32117   1.000 20.43504  ? 116 PHE L CD1  1 
ATOM   5043 C CD2  . PHE B 2 122 ? 25.38250  9.89728   0.95145   1.000 26.01490  ? 116 PHE L CD2  1 
ATOM   5044 C CE1  . PHE B 2 122 ? 24.13104  10.62470  3.29466   1.000 23.81891  ? 116 PHE L CE1  1 
ATOM   5045 C CE2  . PHE B 2 122 ? 26.08403  10.58236  1.92003   1.000 28.05494  ? 116 PHE L CE2  1 
ATOM   5046 C CZ   . PHE B 2 122 ? 25.45793  10.94601  3.09302   1.000 28.31126  ? 116 PHE L CZ   1 
ATOM   5047 H H    . PHE B 2 122 ? 20.90149  10.13013  0.27573   1.000 18.94218  ? 116 PHE L H    1 
ATOM   5048 H HA   . PHE B 2 122 ? 23.06005  10.26901  -1.35846  1.000 19.42889  ? 116 PHE L HA   1 
ATOM   5049 H HB2  . PHE B 2 122 ? 22.70155  8.20147   0.54234   1.000 24.18294  ? 116 PHE L HB2  1 
ATOM   5050 H HB3  . PHE B 2 122 ? 23.94088  8.33303   -0.44364  1.000 24.18294  ? 116 PHE L HB3  1 
ATOM   5051 H HD1  . PHE B 2 122 ? 22.53938  9.72513   2.46140   1.000 24.52888  ? 116 PHE L HD1  1 
ATOM   5052 H HD2  . PHE B 2 122 ? 25.80958  9.64916   0.16345   1.000 31.22471  ? 116 PHE L HD2  1 
ATOM   5053 H HE1  . PHE B 2 122 ? 23.70805  10.86875  4.08613   1.000 28.58953  ? 116 PHE L HE1  1 
ATOM   5054 H HE2  . PHE B 2 122 ? 26.97797  10.79884  1.78250   1.000 33.67276  ? 116 PHE L HE2  1 
ATOM   5055 H HZ   . PHE B 2 122 ? 25.92952  11.40771  3.74826   1.000 33.98035  ? 116 PHE L HZ   1 
ATOM   5056 N N    . ILE B 2 123 ? 22.23530  8.52917   -2.95380  1.000 18.66530  ? 117 ILE L N    1 
ATOM   5057 C CA   . ILE B 2 123 ? 21.59282  7.63700   -3.91303  1.000 18.24930  ? 117 ILE L CA   1 
ATOM   5058 C C    . ILE B 2 123 ? 22.55293  6.50164   -4.25278  1.000 19.87488  ? 117 ILE L C    1 
ATOM   5059 O O    . ILE B 2 123 ? 23.76074  6.71492   -4.40544  1.000 15.77356  ? 117 ILE L O    1 
ATOM   5060 C CB   . ILE B 2 123 ? 21.13923  8.38418   -5.18733  1.000 15.82035  ? 117 ILE L CB   1 
ATOM   5061 C CG1  . ILE B 2 123 ? 20.30041  7.45503   -6.06787  1.000 17.30859  ? 117 ILE L CG1  1 
ATOM   5062 C CG2  . ILE B 2 123 ? 22.34850  8.93391   -5.94137  1.000 19.04673  ? 117 ILE L CG2  1 
ATOM   5063 C CD1  . ILE B 2 123 ? 19.48572  8.18010   -7.12080  1.000 20.11118  ? 117 ILE L CD1  1 
ATOM   5064 H H    . ILE B 2 123 ? 22.99366  8.84022   -3.21407  1.000 22.40519  ? 117 ILE L H    1 
ATOM   5065 H HA   . ILE B 2 123 ? 20.80485  7.24938   -3.50102  1.000 21.90599  ? 117 ILE L HA   1 
ATOM   5066 H HB   . ILE B 2 123 ? 20.58400  9.13752   -4.93219  1.000 18.99125  ? 117 ILE L HB   1 
ATOM   5067 H HG12 . ILE B 2 123 ? 20.89408  6.83928   -6.52535  1.000 20.77714  ? 117 ILE L HG12 1 
ATOM   5068 H HG13 . ILE B 2 123 ? 19.68359  6.96346   -5.50325  1.000 20.77714  ? 117 ILE L HG13 1 
ATOM   5069 H HG21 . ILE B 2 123 ? 22.03945  9.52364   -6.64678  1.000 22.86291  ? 117 ILE L HG21 1 
ATOM   5070 H HG22 . ILE B 2 123 ? 22.91030  9.42531   -5.32185  1.000 22.86291  ? 117 ILE L HG22 1 
ATOM   5071 H HG23 . ILE B 2 123 ? 22.84580  8.19376   -6.32316  1.000 22.86291  ? 117 ILE L HG23 1 
ATOM   5072 H HD11 . ILE B 2 123 ? 18.98077  7.52924   -7.63297  1.000 24.14025  ? 117 ILE L HD11 1 
ATOM   5073 H HD12 . ILE B 2 123 ? 18.87998  8.79746   -6.68167  1.000 24.14025  ? 117 ILE L HD12 1 
ATOM   5074 H HD13 . ILE B 2 123 ? 20.08727  8.66672   -7.70581  1.000 24.14025  ? 117 ILE L HD13 1 
ATOM   5075 N N    . PHE B 2 124 ? 22.00491  5.29475   -4.36214  1.000 16.71462  ? 118 PHE L N    1 
ATOM   5076 C CA   . PHE B 2 124 ? 22.75565  4.06432   -4.56509  1.000 17.22305  ? 118 PHE L CA   1 
ATOM   5077 C C    . PHE B 2 124 ? 22.23011  3.35943   -5.80524  1.000 15.97009  ? 118 PHE L C    1 
ATOM   5078 O O    . PHE B 2 124 ? 21.05008  2.95722   -5.82849  1.000 16.87981  ? 118 PHE L O    1 
ATOM   5079 C CB   . PHE B 2 124 ? 22.62734  3.12670   -3.36247  1.000 19.40990  ? 118 PHE L CB   1 
ATOM   5080 C CG   . PHE B 2 124 ? 23.20821  3.67539   -2.09746  1.000 19.79401  ? 118 PHE L CG   1 
ATOM   5081 C CD1  . PHE B 2 124 ? 24.56562  3.56097   -1.83451  1.000 17.81083  ? 118 PHE L CD1  1 
ATOM   5082 C CD2  . PHE B 2 124 ? 22.39924  4.28395   -1.16096  1.000 22.36420  ? 118 PHE L CD2  1 
ATOM   5083 C CE1  . PHE B 2 124 ? 25.09737  4.06183   -0.66835  1.000 18.14693  ? 118 PHE L CE1  1 
ATOM   5084 C CE2  . PHE B 2 124 ? 22.93090  4.78634   0.01269   1.000 23.86263  ? 118 PHE L CE2  1 
ATOM   5085 C CZ   . PHE B 2 124 ? 24.28240  4.67415   0.25435   1.000 23.83309  ? 118 PHE L CZ   1 
ATOM   5086 H H    . PHE B 2 124 ? 21.15688  5.15825   -4.31961  1.000 20.06438  ? 118 PHE L H    1 
ATOM   5087 H HA   . PHE B 2 124 ? 23.69105  4.28979   -4.68795  1.000 20.67449  ? 118 PHE L HA   1 
ATOM   5088 H HB2  . PHE B 2 124 ? 21.68653  2.95203   -3.20350  1.000 23.29871  ? 118 PHE L HB2  1 
ATOM   5089 H HB3  . PHE B 2 124 ? 23.08924  2.29785   -3.56387  1.000 23.29871  ? 118 PHE L HB3  1 
ATOM   5090 H HD1  . PHE B 2 124 ? 25.12100  3.14212   -2.45177  1.000 21.37983  ? 118 PHE L HD1  1 
ATOM   5091 H HD2  . PHE B 2 124 ? 21.48596  4.35731   -1.32045  1.000 26.84387  ? 118 PHE L HD2  1 
ATOM   5092 H HE1  . PHE B 2 124 ? 26.00959  3.98602   -0.50403  1.000 21.78314  ? 118 PHE L HE1  1 
ATOM   5093 H HE2  . PHE B 2 124 ? 22.37794  5.19849   0.63661   1.000 28.64199  ? 118 PHE L HE2  1 
ATOM   5094 H HZ   . PHE B 2 124 ? 24.64364  5.01260   1.04166   1.000 28.60654  ? 118 PHE L HZ   1 
ATOM   5095 N N    . PRO B 2 125 ? 23.04855  3.17146   -6.83544  1.000 19.95027  ? 119 PRO L N    1 
ATOM   5096 C CA   . PRO B 2 125 ? 22.62724  2.36463   -7.96800  1.000 17.44352  ? 119 PRO L CA   1 
ATOM   5097 C C    . PRO B 2 125 ? 22.55386  0.90179   -7.57397  1.000 19.05937  ? 119 PRO L C    1 
ATOM   5098 O O    . PRO B 2 125 ? 23.13304  0.49269   -6.55644  1.000 18.33742  ? 119 PRO L O    1 
ATOM   5099 C CB   . PRO B 2 125 ? 23.72897  2.60099   -9.01589  1.000 17.51305  ? 119 PRO L CB   1 
ATOM   5100 C CG   . PRO B 2 125 ? 24.56212  3.69620   -8.50538  1.000 21.13636  ? 119 PRO L CG   1 
ATOM   5101 C CD   . PRO B 2 125 ? 24.40040  3.72192   -7.02665  1.000 20.06209  ? 119 PRO L CD   1 
ATOM   5102 H HA   . PRO B 2 125 ? 21.77481  2.66774   -8.31785  1.000 20.93906  ? 119 PRO L HA   1 
ATOM   5103 H HB2  . PRO B 2 125 ? 24.25452  1.79256   -9.12140  1.000 21.02250  ? 119 PRO L HB2  1 
ATOM   5104 H HB3  . PRO B 2 125 ? 23.32371  2.84607   -9.86242  1.000 21.02250  ? 119 PRO L HB3  1 
ATOM   5105 H HG2  . PRO B 2 125 ? 25.48852  3.53220   -8.74158  1.000 25.37047  ? 119 PRO L HG2  1 
ATOM   5106 H HG3  . PRO B 2 125 ? 24.26426  4.53406   -8.89290  1.000 25.37047  ? 119 PRO L HG3  1 
ATOM   5107 H HD2  . PRO B 2 125 ? 25.06634  3.16409   -6.59509  1.000 24.08134  ? 119 PRO L HD2  1 
ATOM   5108 H HD3  . PRO B 2 125 ? 24.45688  4.62883   -6.68723  1.000 24.08134  ? 119 PRO L HD3  1 
ATOM   5109 N N    . PRO B 2 126 ? 21.86477  0.08257   -8.35480  1.000 19.99325  ? 120 PRO L N    1 
ATOM   5110 C CA   . PRO B 2 126 ? 21.87878  -1.35716  -8.08758  1.000 19.44451  ? 120 PRO L CA   1 
ATOM   5111 C C    . PRO B 2 126 ? 23.26652  -1.93463  -8.28497  1.000 17.76915  ? 120 PRO L C    1 
ATOM   5112 O O    . PRO B 2 126 ? 24.04619  -1.47511  -9.12138  1.000 17.41743  ? 120 PRO L O    1 
ATOM   5113 C CB   . PRO B 2 126 ? 20.88964  -1.91950  -9.11193  1.000 24.29331  ? 120 PRO L CB   1 
ATOM   5114 C CG   . PRO B 2 126 ? 20.86967  -0.91688  -10.20471 1.000 25.38345  ? 120 PRO L CG   1 
ATOM   5115 C CD   . PRO B 2 126 ? 21.08732  0.41518   -9.56363  1.000 19.87301  ? 120 PRO L CD   1 
ATOM   5116 H HA   . PRO B 2 126 ? 21.56311  -1.55211  -7.19134  1.000 23.34024  ? 120 PRO L HA   1 
ATOM   5117 H HB2  . PRO B 2 126 ? 21.19988  -2.78010  -9.43445  1.000 29.15881  ? 120 PRO L HB2  1 
ATOM   5118 H HB3  . PRO B 2 126 ? 20.01231  -2.01291  -8.70886  1.000 29.15881  ? 120 PRO L HB3  1 
ATOM   5119 H HG2  . PRO B 2 126 ? 21.57960  -1.11141  -10.83642 1.000 30.46697  ? 120 PRO L HG2  1 
ATOM   5120 H HG3  . PRO B 2 126 ? 20.01003  -0.94308  -10.65331 1.000 30.46697  ? 120 PRO L HG3  1 
ATOM   5121 H HD2  . PRO B 2 126 ? 21.59161  1.00217   -10.14847 1.000 23.85445  ? 120 PRO L HD2  1 
ATOM   5122 H HD3  . PRO B 2 126 ? 20.24170  0.82798   -9.32823  1.000 23.85445  ? 120 PRO L HD3  1 
ATOM   5123 N N    . SER B 2 127 ? 23.56629  -2.96231  -7.50172  1.000 21.18662  ? 121 SER L N    1 
ATOM   5124 C CA   . SER B 2 127 ? 24.83776  -3.65165  -7.61813  1.000 27.68191  ? 121 SER L CA   1 
ATOM   5125 C C    . SER B 2 127 ? 24.83308  -4.56517  -8.83609  1.000 25.00892  ? 121 SER L C    1 
ATOM   5126 O O    . SER B 2 127 ? 23.78830  -5.05736  -9.26889  1.000 19.25814  ? 121 SER L O    1 
ATOM   5127 C CB   . SER B 2 127 ? 25.11746  -4.47887  -6.36469  1.000 26.35743  ? 121 SER L CB   1 
ATOM   5128 O OG   . SER B 2 127 ? 24.23233  -5.58505  -6.28658  1.000 25.07919  ? 121 SER L OG   1 
ATOM   5129 H H    . SER B 2 127 ? 23.04724  -3.27914  -6.89361  1.000 25.43078  ? 121 SER L H    1 
ATOM   5130 H HA   . SER B 2 127 ? 25.54958  -3.00033  -7.71813  1.000 33.22512  ? 121 SER L HA   1 
ATOM   5131 H HB2  . SER B 2 127 ? 26.03013  -4.80568  -6.39841  1.000 31.63574  ? 121 SER L HB2  1 
ATOM   5132 H HB3  . SER B 2 127 ? 24.99420  -3.91912  -5.58214  1.000 31.63574  ? 121 SER L HB3  1 
ATOM   5133 H HG   . SER B 2 127 ? 23.43733  -5.31536  -6.25738  1.000 30.10186  ? 121 SER L HG   1 
ATOM   5134 N N    . ASP B 2 128 ? 26.02387  -4.80500  -9.38392  1.000 27.64772  ? 122 ASP L N    1 
ATOM   5135 C CA   . ASP B 2 128 ? 26.12898  -5.76206  -10.48030 1.000 30.44989  ? 122 ASP L CA   1 
ATOM   5136 C C    . ASP B 2 128 ? 25.67102  -7.14557  -10.03087 1.000 24.78047  ? 122 ASP L C    1 
ATOM   5137 O O    . ASP B 2 128 ? 24.99914  -7.86820  -10.78531 1.000 29.16176  ? 122 ASP L O    1 
ATOM   5138 C CB   . ASP B 2 128 ? 27.56435  -5.78513  -11.00130 1.000 37.14194  ? 122 ASP L CB   1 
ATOM   5139 C CG   . ASP B 2 128 ? 27.99592  -4.43830  -11.57129 1.000 47.37237  ? 122 ASP L CG   1 
ATOM   5140 O OD1  . ASP B 2 128 ? 27.11496  -3.67463  -12.02766 1.000 41.46055  ? 122 ASP L OD1  1 
ATOM   5141 O OD2  . ASP B 2 128 ? 29.21019  -4.14014  -11.56207 1.000 49.68910  ? 122 ASP L OD2  1 
ATOM   5142 H H    . ASP B 2 128 ? 26.76411  -4.43751  -9.14601  1.000 33.18409  ? 122 ASP L H    1 
ATOM   5143 H HA   . ASP B 2 128 ? 25.55709  -5.48923  -11.21475 1.000 36.54670  ? 122 ASP L HA   1 
ATOM   5144 H HB2  . ASP B 2 128 ? 28.16335  -6.01008  -10.27226 1.000 44.57716  ? 122 ASP L HB2  1 
ATOM   5145 H HB3  . ASP B 2 128 ? 27.63591  -6.44784  -11.70599 1.000 44.57716  ? 122 ASP L HB3  1 
ATOM   5146 N N    . GLU B 2 129 ? 25.98981  -7.51286  -8.78423  1.000 26.40566  ? 123 GLU L N    1 
ATOM   5147 C CA   . GLU B 2 129 ? 25.53149  -8.78540  -8.23763  1.000 24.93797  ? 123 GLU L CA   1 
ATOM   5148 C C    . GLU B 2 129 ? 24.02379  -8.92046  -8.37861  1.000 29.33646  ? 123 GLU L C    1 
ATOM   5149 O O    . GLU B 2 129 ? 23.52369  -9.92131  -8.90485  1.000 31.20767  ? 123 GLU L O    1 
ATOM   5150 C CB   . GLU B 2 129 ? 25.93500  -8.91721  -6.76541  1.000 28.56670  ? 123 GLU L CB   1 
ATOM   5151 C CG   . GLU B 2 129 ? 27.42931  -8.90152  -6.50524  1.000 54.58012  ? 123 GLU L CG   1 
ATOM   5152 C CD   . GLU B 2 129 ? 27.93853  -7.53892  -6.06795  1.000 57.19994  ? 123 GLU L CD   1 
ATOM   5153 O OE1  . GLU B 2 129 ? 27.74612  -6.55235  -6.81747  1.000 42.76742  ? 123 GLU L OE1  1 
ATOM   5154 O OE2  . GLU B 2 129 ? 28.53056  -7.46053  -4.96804  1.000 47.60324  ? 123 GLU L OE2  1 
ATOM   5155 H H    . GLU B 2 129 ? 26.46612  -7.04496  -8.24220  1.000 31.69362  ? 123 GLU L H    1 
ATOM   5156 H HA   . GLU B 2 129 ? 25.96025  -9.50281  -8.72996  1.000 29.93240  ? 123 GLU L HA   1 
ATOM   5157 H HB2  . GLU B 2 129 ? 25.54655  -8.17700  -6.27339  1.000 34.28688  ? 123 GLU L HB2  1 
ATOM   5158 H HB3  . GLU B 2 129 ? 25.58988  -9.75814  -6.42683  1.000 34.28688  ? 123 GLU L HB3  1 
ATOM   5159 H HG2  . GLU B 2 129 ? 27.63390  -9.53742  -5.80191  1.000 65.50298  ? 123 GLU L HG2  1 
ATOM   5160 H HG3  . GLU B 2 129 ? 27.89417  -9.14740  -7.32031  1.000 65.50298  ? 123 GLU L HG3  1 
ATOM   5161 N N    . GLN B 2 130 ? 23.27681  -7.91089  -7.91419  1.000 26.46863  ? 124 GLN L N    1 
ATOM   5162 C CA   . GLN B 2 130 ? 21.82380  -7.98586  -8.00868  1.000 24.15794  ? 124 GLN L CA   1 
ATOM   5163 C C    . GLN B 2 130 ? 21.37315  -8.03062  -9.45984  1.000 25.16929  ? 124 GLN L C    1 
ATOM   5164 O O    . GLN B 2 130 ? 20.47119  -8.79749  -9.81310  1.000 25.29916  ? 124 GLN L O    1 
ATOM   5165 C CB   . GLN B 2 130 ? 21.16022  -6.80497  -7.29868  1.000 20.77794  ? 124 GLN L CB   1 
ATOM   5166 C CG   . GLN B 2 130 ? 19.63841  -6.91931  -7.30692  1.000 25.75480  ? 124 GLN L CG   1 
ATOM   5167 C CD   . GLN B 2 130 ? 18.90933  -5.68712  -6.80426  1.000 25.51609  ? 124 GLN L CD   1 
ATOM   5168 O OE1  . GLN B 2 130 ? 19.44514  -4.57816  -6.79485  1.000 19.31637  ? 124 GLN L OE1  1 
ATOM   5169 N NE2  . GLN B 2 130 ? 17.65990  -5.88124  -6.39662  1.000 25.28773  ? 124 GLN L NE2  1 
ATOM   5170 H H    . GLN B 2 130 ? 23.58210  -7.19362  -7.55098  1.000 31.76919  ? 124 GLN L H    1 
ATOM   5171 H HA   . GLN B 2 130 ? 21.53879  -8.79784  -7.56106  1.000 28.99636  ? 124 GLN L HA   1 
ATOM   5172 H HB2  . GLN B 2 130 ? 21.45831  -6.77894  -6.37599  1.000 24.94036  ? 124 GLN L HB2  1 
ATOM   5173 H HB3  . GLN B 2 130 ? 21.40589  -5.98227  -7.75002  1.000 24.94036  ? 124 GLN L HB3  1 
ATOM   5174 H HG2  . GLN B 2 130 ? 19.34566  -7.08067  -8.21751  1.000 30.91260  ? 124 GLN L HG2  1 
ATOM   5175 H HG3  . GLN B 2 130 ? 19.38138  -7.66261  -6.73917  1.000 30.91260  ? 124 GLN L HG3  1 
ATOM   5176 H HE21 . GLN B 2 130 ? 17.31463  -6.66825  -6.42830  1.000 30.35211  ? 124 GLN L HE21 1 
ATOM   5177 H HE22 . GLN B 2 130 ? 17.19636  -5.21990  -6.10106  1.000 30.35211  ? 124 GLN L HE22 1 
ATOM   5178 N N    . LEU B 2 131 ? 21.96793  -7.19485  -10.31280 1.000 24.29594  ? 125 LEU L N    1 
ATOM   5179 C CA   . LEU B 2 131 ? 21.55928  -7.18968  -11.71227 1.000 28.77264  ? 125 LEU L CA   1 
ATOM   5180 C C    . LEU B 2 131 ? 21.63908  -8.58994  -12.29706 1.000 28.47853  ? 125 LEU L C    1 
ATOM   5181 O O    . LEU B 2 131 ? 20.78656  -8.98071  -13.10115 1.000 26.74734  ? 125 LEU L O    1 
ATOM   5182 C CB   . LEU B 2 131 ? 22.41995  -6.20932  -12.50783 1.000 26.78348  ? 125 LEU L CB   1 
ATOM   5183 C CG   . LEU B 2 131 ? 22.17661  -4.73431  -12.17419 1.000 26.91605  ? 125 LEU L CG   1 
ATOM   5184 C CD1  . LEU B 2 131 ? 23.08909  -3.84188  -12.99230 1.000 29.58035  ? 125 LEU L CD1  1 
ATOM   5185 C CD2  . LEU B 2 131 ? 20.71445  -4.37011  -12.40314 1.000 23.02054  ? 125 LEU L CD2  1 
ATOM   5186 H H    . LEU B 2 131 ? 22.59170  -6.63834  -10.11075 1.000 29.16197  ? 125 LEU L H    1 
ATOM   5187 H HA   . LEU B 2 131 ? 20.64182  -6.88348  -11.78579 1.000 34.53400  ? 125 LEU L HA   1 
ATOM   5188 H HB2  . LEU B 2 131 ? 23.35333  -6.40120  -12.32647 1.000 32.14701  ? 125 LEU L HB2  1 
ATOM   5189 H HB3  . LEU B 2 131 ? 22.23351  -6.33138  -13.45189 1.000 32.14701  ? 125 LEU L HB3  1 
ATOM   5190 H HG   . LEU B 2 131 ? 22.37939  -4.58488  -11.23747 1.000 32.30609  ? 125 LEU L HG   1 
ATOM   5191 H HD11 . LEU B 2 131 ? 22.91946  -2.91626  -12.75700 1.000 35.50326  ? 125 LEU L HD11 1 
ATOM   5192 H HD12 . LEU B 2 131 ? 24.01155  -4.06921  -12.79662 1.000 35.50326  ? 125 LEU L HD12 1 
ATOM   5193 H HD13 . LEU B 2 131 ? 22.90649  -3.98246  -13.93453 1.000 35.50326  ? 125 LEU L HD13 1 
ATOM   5194 H HD21 . LEU B 2 131 ? 20.63554  -3.40543  -12.46689 1.000 27.63148  ? 125 LEU L HD21 1 
ATOM   5195 H HD22 . LEU B 2 131 ? 20.41177  -4.78196  -13.22756 1.000 27.63148  ? 125 LEU L HD22 1 
ATOM   5196 H HD23 . LEU B 2 131 ? 20.18717  -4.69656  -11.65728 1.000 27.63148  ? 125 LEU L HD23 1 
ATOM   5197 N N    . LYS B 2 132 ? 22.61626  -9.38408  -11.86270 1.000 30.15007  ? 126 LYS L N    1 
ATOM   5198 C CA   . LYS B 2 132 ? 22.65809  -10.76404 -12.33527 1.000 32.50947  ? 126 LYS L CA   1 
ATOM   5199 C C    . LYS B 2 132 ? 21.46320  -11.60442 -11.88725 1.000 37.84100  ? 126 LYS L C    1 
ATOM   5200 O O    . LYS B 2 132 ? 21.35529  -12.75698 -12.31537 1.000 41.41381  ? 126 LYS L O    1 
ATOM   5201 C CB   . LYS B 2 132 ? 23.95698  -11.42105 -11.88156 1.000 33.36649  ? 126 LYS L CB   1 
ATOM   5202 C CG   . LYS B 2 132 ? 25.14309  -10.88917 -12.64019 1.000 35.11844  ? 126 LYS L CG   1 
ATOM   5203 C CD   . LYS B 2 132 ? 26.39036  -11.69061 -12.37590 1.000 41.32054  ? 126 LYS L CD   1 
ATOM   5204 C CE   . LYS B 2 132 ? 27.12767  -11.18040 -11.16274 1.000 46.63594  ? 126 LYS L CE   1 
ATOM   5205 N NZ   . LYS B 2 132 ? 28.56548  -11.48574 -11.30065 1.000 47.28604  ? 126 LYS L NZ   1 
ATOM   5206 H H    . LYS B 2 132 ? 23.24077  -9.15669  -11.31691 1.000 36.18692  ? 126 LYS L H    1 
ATOM   5207 H HA   . LYS B 2 132 ? 22.64270  -10.75201 -13.30508 1.000 39.01820  ? 126 LYS L HA   1 
ATOM   5208 H HB2  . LYS B 2 132 ? 24.09328  -11.24227 -10.93797 1.000 40.04662  ? 126 LYS L HB2  1 
ATOM   5209 H HB3  . LYS B 2 132 ? 23.90171  -12.37750 -12.03340 1.000 40.04662  ? 126 LYS L HB3  1 
ATOM   5210 H HG2  . LYS B 2 132 ? 24.95604  -10.92583 -13.59128 1.000 42.14896  ? 126 LYS L HG2  1 
ATOM   5211 H HG3  . LYS B 2 132 ? 25.30975  -9.97260  -12.36994 1.000 42.14896  ? 126 LYS L HG3  1 
ATOM   5212 H HD2  . LYS B 2 132 ? 26.14990  -12.61719 -12.21932 1.000 49.59148  ? 126 LYS L HD2  1 
ATOM   5213 H HD3  . LYS B 2 132 ? 26.98208  -11.62629 -13.14182 1.000 49.59148  ? 126 LYS L HD3  1 
ATOM   5214 H HE2  . LYS B 2 132 ? 27.01618  -10.21962 -11.08947 1.000 55.96996  ? 126 LYS L HE2  1 
ATOM   5215 H HE3  . LYS B 2 132 ? 26.78929  -11.61548 -10.36454 1.000 55.96996  ? 126 LYS L HE3  1 
ATOM   5216 H HZ1  . LYS B 2 132 ? 29.00801  -11.19722 -10.58439 1.000 56.75008  ? 126 LYS L HZ1  1 
ATOM   5217 H HZ2  . LYS B 2 132 ? 28.68395  -12.36435 -11.37883 1.000 56.75008  ? 126 LYS L HZ2  1 
ATOM   5218 H HZ3  . LYS B 2 132 ? 28.89385  -11.08452 -12.02404 1.000 56.75008  ? 126 LYS L HZ3  1 
ATOM   5219 N N    . SER B 2 133 ? 20.57082  -11.07325 -11.05128 1.000 35.90464  ? 127 SER L N    1 
ATOM   5220 C CA   . SER B 2 133 ? 19.35981  -11.77408 -10.64546 1.000 35.80896  ? 127 SER L CA   1 
ATOM   5221 C C    . SER B 2 133 ? 18.14593  -11.40776 -11.49109 1.000 40.35130  ? 127 SER L C    1 
ATOM   5222 O O    . SER B 2 133 ? 17.06665  -11.97024 -11.27647 1.000 38.53419  ? 127 SER L O    1 
ATOM   5223 C CB   . SER B 2 133 ? 19.04595  -11.47591 -9.17655  1.000 31.84987  ? 127 SER L CB   1 
ATOM   5224 O OG   . SER B 2 133 ? 18.47346  -10.18240 -9.03735  1.000 40.21762  ? 127 SER L OG   1 
ATOM   5225 H H    . SER B 2 133 ? 20.64913  -10.29203 -10.70034 1.000 43.09240  ? 127 SER L H    1 
ATOM   5226 H HA   . SER B 2 133 ? 19.51731  -12.72659 -10.73939 1.000 42.97759  ? 127 SER L HA   1 
ATOM   5227 H HB2  . SER B 2 133 ? 18.41742  -12.13711 -8.84690  1.000 38.22667  ? 127 SER L HB2  1 
ATOM   5228 H HB3  . SER B 2 133 ? 19.86809  -11.51482 -8.66326  1.000 38.22667  ? 127 SER L HB3  1 
ATOM   5229 H HG   . SER B 2 133 ? 18.99852  -9.60158  -9.34159  1.000 48.26797  ? 127 SER L HG   1 
ATOM   5230 N N    . GLY B 2 134 ? 18.28367  -10.46951 -12.42514 1.000 33.29834  ? 128 GLY L N    1 
ATOM   5231 C CA   . GLY B 2 134 ? 17.16027  -10.02412 -13.22088 1.000 31.38277  ? 128 GLY L CA   1 
ATOM   5232 C C    . GLY B 2 134 ? 16.35946  -8.88250  -12.63181 1.000 31.77205  ? 128 GLY L C    1 
ATOM   5233 O O    . GLY B 2 134 ? 15.39996  -8.42922  -13.27257 1.000 30.22619  ? 128 GLY L O    1 
ATOM   5234 H H    . GLY B 2 134 ? 19.02554  -10.07714 -12.61295 1.000 39.96485  ? 128 GLY L H    1 
ATOM   5235 H HA2  . GLY B 2 134 ? 17.49036  -9.73536  -14.08608 1.000 37.66616  ? 128 GLY L HA2  1 
ATOM   5236 H HA3  . GLY B 2 134 ? 16.55584  -10.77221 -13.34710 1.000 37.66616  ? 128 GLY L HA3  1 
ATOM   5237 N N    . THR B 2 135 ? 16.71844  -8.39612  -11.44126 1.000 30.14162  ? 129 THR L N    1 
ATOM   5238 C CA   . THR B 2 135 ? 16.01967  -7.28685  -10.80497 1.000 29.13053  ? 129 THR L CA   1 
ATOM   5239 C C    . THR B 2 135 ? 17.01816  -6.21144  -10.40149 1.000 26.43619  ? 129 THR L C    1 
ATOM   5240 O O    . THR B 2 135 ? 18.18463  -6.49453  -10.12326 1.000 26.17250  ? 129 THR L O    1 
ATOM   5241 C CB   . THR B 2 135 ? 15.22959  -7.74882  -9.57100  1.000 40.63798  ? 129 THR L CB   1 
ATOM   5242 O OG1  . THR B 2 135 ? 14.30263  -8.77213  -9.95430  1.000 42.67322  ? 129 THR L OG1  1 
ATOM   5243 C CG2  . THR B 2 135 ? 14.46239  -6.58129  -8.95020  1.000 36.46940  ? 129 THR L CG2  1 
ATOM   5244 H H    . THR B 2 135 ? 17.37579  -8.70025  -10.97759 1.000 36.17678  ? 129 THR L H    1 
ATOM   5245 H HA   . THR B 2 135 ? 15.39532  -6.89782  -11.43721 1.000 34.96347  ? 129 THR L HA   1 
ATOM   5246 H HB   . THR B 2 135 ? 15.84460  -8.09617  -8.90616  1.000 48.77241  ? 129 THR L HB   1 
ATOM   5247 H HG1  . THR B 2 135 ? 13.86112  -9.02487  -9.28588  1.000 51.21470  ? 129 THR L HG1  1 
ATOM   5248 H HG21 . THR B 2 135 ? 13.80591  -6.91419  -8.31844  1.000 43.77012  ? 129 THR L HG21 1 
ATOM   5249 H HG22 . THR B 2 135 ? 15.07580  -5.99109  -8.48512  1.000 43.77012  ? 129 THR L HG22 1 
ATOM   5250 H HG23 . THR B 2 135 ? 14.00598  -6.07849  -9.64286  1.000 43.77012  ? 129 THR L HG23 1 
ATOM   5251 N N    . ALA B 2 136 ? 16.54847  -4.96622  -10.37623 1.000 23.91796  ? 130 ALA L N    1 
ATOM   5252 C CA   . ALA B 2 136 ? 17.37446  -3.81904  -10.04341 1.000 20.12014  ? 130 ALA L CA   1 
ATOM   5253 C C    . ALA B 2 136 ? 16.65459  -3.00022  -8.98408  1.000 22.74382  ? 130 ALA L C    1 
ATOM   5254 O O    . ALA B 2 136 ? 15.47996  -2.65058  -9.15006  1.000 24.96415  ? 130 ALA L O    1 
ATOM   5255 C CB   . ALA B 2 136 ? 17.66231  -2.96593  -11.28325 1.000 21.22844  ? 130 ALA L CB   1 
ATOM   5256 H H    . ALA B 2 136 ? 15.73264  -4.75985  -10.55353 1.000 28.70839  ? 130 ALA L H    1 
ATOM   5257 H HA   . ALA B 2 136 ? 18.22487  -4.11308  -9.68114  1.000 24.15100  ? 130 ALA L HA   1 
ATOM   5258 H HB1  . ALA B 2 136 ? 18.21998  -2.21472  -11.02716 1.000 25.48096  ? 130 ALA L HB1  1 
ATOM   5259 H HB2  . ALA B 2 136 ? 18.12235  -3.51025  -11.94126 1.000 25.48096  ? 130 ALA L HB2  1 
ATOM   5260 H HB3  . ALA B 2 136 ? 16.82258  -2.64535  -11.64790 1.000 25.48096  ? 130 ALA L HB3  1 
ATOM   5261 N N    . SER B 2 137 ? 17.35998  -2.71589  -7.89396  1.000 18.39815  ? 131 SER L N    1 
ATOM   5262 C CA   . SER B 2 137 ? 16.86888  -1.87376  -6.81118  1.000 19.40692  ? 131 SER L CA   1 
ATOM   5263 C C    . SER B 2 137 ? 17.73968  -0.62942  -6.74898  1.000 17.42693  ? 131 SER L C    1 
ATOM   5264 O O    . SER B 2 137 ? 18.96616  -0.73112  -6.63936  1.000 19.42919  ? 131 SER L O    1 
ATOM   5265 C CB   . SER B 2 137 ? 16.90058  -2.61309  -5.47297  1.000 17.52492  ? 131 SER L CB   1 
ATOM   5266 O OG   . SER B 2 137 ? 16.10187  -3.77897  -5.51474  1.000 21.82647  ? 131 SER L OG   1 
ATOM   5267 H H    . SER B 2 137 ? 18.15568  -3.01099  -7.75477  1.000 22.08462  ? 131 SER L H    1 
ATOM   5268 H HA   . SER B 2 137 ? 15.95210  -1.61252  -6.99051  1.000 23.29514  ? 131 SER L HA   1 
ATOM   5269 H HB2  . SER B 2 137 ? 17.81589  -2.86590  -5.27498  1.000 21.03673  ? 131 SER L HB2  1 
ATOM   5270 H HB3  . SER B 2 137 ? 16.56177  -2.02447  -4.78041  1.000 21.03673  ? 131 SER L HB3  1 
ATOM   5271 H HG   . SER B 2 137 ? 15.30188  -3.57383  -5.66815  1.000 26.19860  ? 131 SER L HG   1 
ATOM   5272 N N    . VAL B 2 138 ? 17.11387  0.53598   -6.84668  1.000 17.38004  ? 132 VAL L N    1 
ATOM   5273 C CA   . VAL B 2 138 ? 17.79492  1.81522   -6.68793  1.000 16.97348  ? 132 VAL L CA   1 
ATOM   5274 C C    . VAL B 2 138 ? 17.35607  2.39573   -5.35689  1.000 16.20769  ? 132 VAL L C    1 
ATOM   5275 O O    . VAL B 2 138 ? 16.15311  2.47199   -5.08076  1.000 15.98834  ? 132 VAL L O    1 
ATOM   5276 C CB   . VAL B 2 138 ? 17.47795  2.78235   -7.83918  1.000 17.42004  ? 132 VAL L CB   1 
ATOM   5277 C CG1  . VAL B 2 138 ? 18.49086  3.93199   -7.84482  1.000 16.87698  ? 132 VAL L CG1  1 
ATOM   5278 C CG2  . VAL B 2 138 ? 17.48842  2.05022   -9.15657  1.000 20.40723  ? 132 VAL L CG2  1 
ATOM   5279 H H    . VAL B 2 138 ? 16.27284  0.61367   -7.00862  1.000 20.86288  ? 132 VAL L H    1 
ATOM   5280 H HA   . VAL B 2 138 ? 18.75465  1.67484   -6.67710  1.000 20.37501  ? 132 VAL L HA   1 
ATOM   5281 H HB   . VAL B 2 138 ? 16.59156  3.15598   -7.71426  1.000 20.91088  ? 132 VAL L HB   1 
ATOM   5282 H HG11 . VAL B 2 138 ? 18.27739  4.53741   -8.57201  1.000 20.25921  ? 132 VAL L HG11 1 
ATOM   5283 H HG12 . VAL B 2 138 ? 18.44017  4.40171   -6.99765  1.000 20.25921  ? 132 VAL L HG12 1 
ATOM   5284 H HG13 . VAL B 2 138 ? 19.38134  3.56771   -7.96829  1.000 20.25921  ? 132 VAL L HG13 1 
ATOM   5285 H HG21 . VAL B 2 138 ? 17.69754  2.67852   -9.86538  1.000 24.49551  ? 132 VAL L HG21 1 
ATOM   5286 H HG22 . VAL B 2 138 ? 18.16093  1.35194   -9.12446  1.000 24.49551  ? 132 VAL L HG22 1 
ATOM   5287 H HG23 . VAL B 2 138 ? 16.61338  1.66000   -9.30796  1.000 24.49551  ? 132 VAL L HG23 1 
ATOM   5288 N N    . VAL B 2 139 ? 18.31936  2.78806   -4.52041  1.000 19.85623  ? 133 VAL L N    1 
ATOM   5289 C CA   . VAL B 2 139 ? 18.01431  3.18509   -3.14846  1.000 17.31076  ? 133 VAL L CA   1 
ATOM   5290 C C    . VAL B 2 139 ? 18.34721  4.65615   -2.94796  1.000 16.28368  ? 133 VAL L C    1 
ATOM   5291 O O    . VAL B 2 139 ? 19.43102  5.11322   -3.31740  1.000 17.25836  ? 133 VAL L O    1 
ATOM   5292 C CB   . VAL B 2 139 ? 18.76252  2.31413   -2.12177  1.000 14.96262  ? 133 VAL L CB   1 
ATOM   5293 C CG1  . VAL B 2 139 ? 18.43835  2.77786   -0.69469  1.000 17.24011  ? 133 VAL L CG1  1 
ATOM   5294 C CG2  . VAL B 2 139 ? 18.37945  0.84696   -2.30843  1.000 22.87539  ? 133 VAL L CG2  1 
ATOM   5295 H H    . VAL B 2 139 ? 19.15316  2.83142   -4.72658  1.000 23.83431  ? 133 VAL L H    1 
ATOM   5296 H HA   . VAL B 2 139 ? 17.05949  3.08297   -3.01139  1.000 20.77975  ? 133 VAL L HA   1 
ATOM   5297 H HB   . VAL B 2 139 ? 19.71862  2.40354   -2.25881  1.000 17.96197  ? 133 VAL L HB   1 
ATOM   5298 H HG11 . VAL B 2 139 ? 18.74247  2.10387   -0.06687  1.000 20.69496  ? 133 VAL L HG11 1 
ATOM   5299 H HG12 . VAL B 2 139 ? 18.89309  3.61760   -0.52454  1.000 20.69496  ? 133 VAL L HG12 1 
ATOM   5300 H HG13 . VAL B 2 139 ? 17.47941  2.89829   -0.61193  1.000 20.69496  ? 133 VAL L HG13 1 
ATOM   5301 H HG21 . VAL B 2 139 ? 18.81742  0.31673   -1.62437  1.000 27.45730  ? 133 VAL L HG21 1 
ATOM   5302 H HG22 . VAL B 2 139 ? 17.41668  0.75937   -2.22895  1.000 27.45730  ? 133 VAL L HG22 1 
ATOM   5303 H HG23 . VAL B 2 139 ? 18.66669  0.55498   -3.18771  1.000 27.45730  ? 133 VAL L HG23 1 
ATOM   5304 N N    . CYS B 2 140 ? 17.41566  5.39104   -2.35326  1.000 19.07744  ? 134 CYS L N    1 
ATOM   5305 C CA   . CYS B 2 140 ? 17.61128  6.77064   -1.93086  1.000 16.90489  ? 134 CYS L CA   1 
ATOM   5306 C C    . CYS B 2 140 ? 17.52703  6.80018   -0.40983  1.000 16.71436  ? 134 CYS L C    1 
ATOM   5307 O O    . CYS B 2 140 ? 16.54939  6.31702   0.16746   1.000 18.96851  ? 134 CYS L O    1 
ATOM   5308 C CB   . CYS B 2 140 ? 16.55518  7.68260   -2.55910  1.000 18.38215  ? 134 CYS L CB   1 
ATOM   5309 S SG   . CYS B 2 140 ? 16.81142  9.47854   -2.38845  1.000 26.20160  ? 134 CYS L SG   1 
ATOM   5310 H H    . CYS B 2 140 ? 16.62661  5.09848   -2.17602  1.000 22.89977  ? 134 CYS L H    1 
ATOM   5311 H HA   . CYS B 2 140 ? 18.48017  7.10302   -2.20555  1.000 20.29270  ? 134 CYS L HA   1 
ATOM   5312 H HB2  . CYS B 2 140 ? 16.52076  7.49081   -3.50933  1.000 22.06542  ? 134 CYS L HB2  1 
ATOM   5313 H HB3  . CYS B 2 140 ? 15.70049  7.47851   -2.14829  1.000 22.06542  ? 134 CYS L HB3  1 
ATOM   5314 N N    . LEU B 2 141 ? 18.55867  7.33966   0.23005   1.000 16.23774  ? 135 LEU L N    1 
ATOM   5315 C CA   . LEU B 2 141 ? 18.63731  7.47757   1.67676   1.000 17.03515  ? 135 LEU L CA   1 
ATOM   5316 C C    . LEU B 2 141 ? 18.51110  8.94544   2.05878   1.000 15.64604  ? 135 LEU L C    1 
ATOM   5317 O O    . LEU B 2 141 ? 19.24518  9.78882   1.53573   1.000 17.43475  ? 135 LEU L O    1 
ATOM   5318 C CB   . LEU B 2 141 ? 19.96247  6.91995   2.19753   1.000 17.03914  ? 135 LEU L CB   1 
ATOM   5319 C CG   . LEU B 2 141 ? 20.33099  7.24005   3.64899   1.000 19.56535  ? 135 LEU L CG   1 
ATOM   5320 C CD1  . LEU B 2 141 ? 19.35875  6.59605   4.61972   1.000 20.00861  ? 135 LEU L CD1  1 
ATOM   5321 C CD2  . LEU B 2 141 ? 21.75506  6.78992   3.93769   1.000 19.41260  ? 135 LEU L CD2  1 
ATOM   5322 H H    . LEU B 2 141 ? 19.25479  7.64599   -0.17141  1.000 19.49213  ? 135 LEU L H    1 
ATOM   5323 H HA   . LEU B 2 141 ? 17.90611  6.99062   2.08802   1.000 20.44901  ? 135 LEU L HA   1 
ATOM   5324 H HB2  . LEU B 2 141 ? 19.93002  5.95353   2.12080   1.000 20.45380  ? 135 LEU L HB2  1 
ATOM   5325 H HB3  . LEU B 2 141 ? 20.67395  7.27324   1.64087   1.000 20.45380  ? 135 LEU L HB3  1 
ATOM   5326 H HG   . LEU B 2 141 ? 20.27710  8.19955   3.78076   1.000 23.48525  ? 135 LEU L HG   1 
ATOM   5327 H HD11 . LEU B 2 141 ? 19.62482  6.81653   5.52609   1.000 24.01717  ? 135 LEU L HD11 1 
ATOM   5328 H HD12 . LEU B 2 141 ? 18.46689  6.93512   4.44505   1.000 24.01717  ? 135 LEU L HD12 1 
ATOM   5329 H HD13 . LEU B 2 141 ? 19.37751  5.63440   4.49415   1.000 24.01717  ? 135 LEU L HD13 1 
ATOM   5330 H HD21 . LEU B 2 141 ? 21.96947  6.99356   4.86152   1.000 23.30195  ? 135 LEU L HD21 1 
ATOM   5331 H HD22 . LEU B 2 141 ? 21.82110  5.83418   3.78572   1.000 23.30195  ? 135 LEU L HD22 1 
ATOM   5332 H HD23 . LEU B 2 141 ? 22.36153  7.26169   3.34564   1.000 23.30195  ? 135 LEU L HD23 1 
ATOM   5333 N N    . LEU B 2 142 ? 17.58166  9.24094   2.96049   1.000 15.90779  ? 136 LEU L N    1 
ATOM   5334 C CA   . LEU B 2 142 ? 17.46500  10.53720  3.61922   1.000 17.61868  ? 136 LEU L CA   1 
ATOM   5335 C C    . LEU B 2 142 ? 17.92343  10.34167  5.05547   1.000 17.86319  ? 136 LEU L C    1 
ATOM   5336 O O    . LEU B 2 142 ? 17.28003  9.60974   5.81413   1.000 19.65233  ? 136 LEU L O    1 
ATOM   5337 C CB   . LEU B 2 142 ? 16.03103  11.05351  3.59738   1.000 19.88865  ? 136 LEU L CB   1 
ATOM   5338 C CG   . LEU B 2 142 ? 15.44854  11.57799  2.28908   1.000 25.23521  ? 136 LEU L CG   1 
ATOM   5339 C CD1  . LEU B 2 142 ? 15.53698  10.52852  1.20273   1.000 22.40658  ? 136 LEU L CD1  1 
ATOM   5340 C CD2  . LEU B 2 142 ? 14.00879  12.00341  2.51589   1.000 25.78892  ? 136 LEU L CD2  1 
ATOM   5341 H H    . LEU B 2 142 ? 16.98096  8.68217   3.21844   1.000 19.09618  ? 136 LEU L H    1 
ATOM   5342 H HA   . LEU B 2 142 ? 18.02716  11.18404  3.16484   1.000 21.14925  ? 136 LEU L HA   1 
ATOM   5343 H HB2  . LEU B 2 142 ? 15.45642  10.32474  3.87954   1.000 23.87321  ? 136 LEU L HB2  1 
ATOM   5344 H HB3  . LEU B 2 142 ? 15.97652  11.78417  4.23304   1.000 23.87321  ? 136 LEU L HB3  1 
ATOM   5345 H HG   . LEU B 2 142 ? 15.95777  12.34671  1.98802   1.000 30.28909  ? 136 LEU L HG   1 
ATOM   5346 H HD11 . LEU B 2 142 ? 14.98492  10.80219  0.45357   1.000 26.89473  ? 136 LEU L HD11 1 
ATOM   5347 H HD12 . LEU B 2 142 ? 16.46086  10.44432  0.91944   1.000 26.89473  ? 136 LEU L HD12 1 
ATOM   5348 H HD13 . LEU B 2 142 ? 15.22054  9.68194   1.55495   1.000 26.89473  ? 136 LEU L HD13 1 
ATOM   5349 H HD21 . LEU B 2 142 ? 13.63553  12.31478  1.67647   1.000 30.95354  ? 136 LEU L HD21 1 
ATOM   5350 H HD22 . LEU B 2 142 ? 13.50227  11.24283  2.84124   1.000 30.95354  ? 136 LEU L HD22 1 
ATOM   5351 H HD23 . LEU B 2 142 ? 13.99021  12.71808  3.17148   1.000 30.95354  ? 136 LEU L HD23 1 
ATOM   5352 N N    . ASN B 2 143 ? 19.02319  10.98160  5.43623   1.000 17.37310  ? 137 ASN L N    1 
ATOM   5353 C CA   . ASN B 2 143 ? 19.64435  10.72817  6.72707   1.000 19.97215  ? 137 ASN L CA   1 
ATOM   5354 C C    . ASN B 2 143 ? 19.40868  11.89407  7.67419   1.000 23.48052  ? 137 ASN L C    1 
ATOM   5355 O O    . ASN B 2 143 ? 19.67800  13.05211  7.32567   1.000 20.52079  ? 137 ASN L O    1 
ATOM   5356 C CB   . ASN B 2 143 ? 21.14395  10.47320  6.57151   1.000 24.71882  ? 137 ASN L CB   1 
ATOM   5357 C CG   . ASN B 2 143 ? 21.66554  9.46253   7.57049   1.000 29.74060  ? 137 ASN L CG   1 
ATOM   5358 O OD1  . ASN B 2 143 ? 20.91676  8.62475   8.07057   1.000 29.34720  ? 137 ASN L OD1  1 
ATOM   5359 N ND2  . ASN B 2 143 ? 22.95234  9.53822   7.87091   1.000 31.13099  ? 137 ASN L ND2  1 
ATOM   5360 H H    . ASN B 2 143 ? 19.42927  11.57085  4.95928   1.000 20.85456  ? 137 ASN L H    1 
ATOM   5361 H HA   . ASN B 2 143 ? 19.23180  9.94331   7.12039   1.000 23.97342  ? 137 ASN L HA   1 
ATOM   5362 H HB2  . ASN B 2 143 ? 21.31698  10.13238  5.67999   1.000 29.66942  ? 137 ASN L HB2  1 
ATOM   5363 H HB3  . ASN B 2 143 ? 21.62302  11.30565  6.70721   1.000 29.66942  ? 137 ASN L HB3  1 
ATOM   5364 H HD21 . ASN B 2 143 ? 23.29579  8.98579   8.43346   1.000 37.36402  ? 137 ASN L HD21 1 
ATOM   5365 H HD22 . ASN B 2 143 ? 23.44500  10.13983  7.50356   1.000 37.36402  ? 137 ASN L HD22 1 
ATOM   5366 N N    . ASN B 2 144 ? 18.88990  11.57100  8.86469   1.000 24.91260  ? 138 ASN L N    1 
ATOM   5367 C CA   . ASN B 2 144 ? 18.84367  12.46195  10.02593  1.000 22.53691  ? 138 ASN L CA   1 
ATOM   5368 C C    . ASN B 2 144 ? 18.11215  13.76791  9.69772   1.000 20.02682  ? 138 ASN L C    1 
ATOM   5369 O O    . ASN B 2 144 ? 18.70214  14.84162  9.59945   1.000 24.30513  ? 138 ASN L O    1 
ATOM   5370 C CB   . ASN B 2 144 ? 20.26162  12.73966  10.54442  1.000 26.48653  ? 138 ASN L CB   1 
ATOM   5371 C CG   . ASN B 2 144 ? 21.00168  11.47052  10.93359  1.000 29.17230  ? 138 ASN L CG   1 
ATOM   5372 O OD1  . ASN B 2 144 ? 20.38989  10.46794  11.30357  1.000 29.48479  ? 138 ASN L OD1  1 
ATOM   5373 N ND2  . ASN B 2 144 ? 22.32547  11.51110  10.85321  1.000 25.04449  ? 138 ASN L ND2  1 
ATOM   5374 H H    . ASN B 2 144 ? 18.54182  10.80221  9.03021   1.000 29.90195  ? 138 ASN L H    1 
ATOM   5375 H HA   . ASN B 2 144 ? 18.33719  12.01730  10.72354  1.000 27.05112  ? 138 ASN L HA   1 
ATOM   5376 H HB2  . ASN B 2 144 ? 20.77167  13.18349  9.84889   1.000 31.79067  ? 138 ASN L HB2  1 
ATOM   5377 H HB3  . ASN B 2 144 ? 20.20620  13.30757  11.32884  1.000 31.79067  ? 138 ASN L HB3  1 
ATOM   5378 H HD21 . ASN B 2 144 ? 22.79040  10.81854  11.06250  1.000 30.06023  ? 138 ASN L HD21 1 
ATOM   5379 H HD22 . ASN B 2 144 ? 22.71856  12.22996  10.59182  1.000 30.06023  ? 138 ASN L HD22 1 
ATOM   5380 N N    . PHE B 2 145 ? 16.79395  13.64923  9.55817   1.000 19.89915  ? 139 PHE L N    1 
ATOM   5381 C CA   . PHE B 2 145 ? 15.95879  14.78730  9.21067   1.000 19.89150  ? 139 PHE L CA   1 
ATOM   5382 C C    . PHE B 2 145 ? 14.75054  14.85775  10.13337  1.000 21.50814  ? 139 PHE L C    1 
ATOM   5383 O O    . PHE B 2 145 ? 14.43829  13.91810  10.87047  1.000 18.11081  ? 139 PHE L O    1 
ATOM   5384 C CB   . PHE B 2 145 ? 15.50441  14.72772  7.74025   1.000 17.29214  ? 139 PHE L CB   1 
ATOM   5385 C CG   . PHE B 2 145 ? 14.52766  13.63493  7.44160   1.000 17.18650  ? 139 PHE L CG   1 
ATOM   5386 C CD1  . PHE B 2 145 ? 14.96453  12.34885  7.18702   1.000 19.11560  ? 139 PHE L CD1  1 
ATOM   5387 C CD2  . PHE B 2 145 ? 13.16870  13.89973  7.37983   1.000 16.84506  ? 139 PHE L CD2  1 
ATOM   5388 C CE1  . PHE B 2 145 ? 14.06062  11.34074  6.89628   1.000 18.97743  ? 139 PHE L CE1  1 
ATOM   5389 C CE2  . PHE B 2 145 ? 12.26265  12.90328  7.09290   1.000 20.73576  ? 139 PHE L CE2  1 
ATOM   5390 C CZ   . PHE B 2 145 ? 12.70723  11.61792  6.85078   1.000 21.00060  ? 139 PHE L CZ   1 
ATOM   5391 H H    . PHE B 2 145 ? 16.36107  12.91328  9.66117   1.000 23.88581  ? 139 PHE L H    1 
ATOM   5392 H HA   . PHE B 2 145 ? 16.47515  15.59815  9.34027   1.000 23.87664  ? 139 PHE L HA   1 
ATOM   5393 H HB2  . PHE B 2 145 ? 15.08123  15.57028  7.51241   1.000 20.75740  ? 139 PHE L HB2  1 
ATOM   5394 H HB3  . PHE B 2 145 ? 16.28393  14.58598  7.18064   1.000 20.75740  ? 139 PHE L HB3  1 
ATOM   5395 H HD1  . PHE B 2 145 ? 15.87451  12.15845  7.21118   1.000 22.94556  ? 139 PHE L HD1  1 
ATOM   5396 H HD2  . PHE B 2 145 ? 12.86371  14.76454  7.53470   1.000 20.22091  ? 139 PHE L HD2  1 
ATOM   5397 H HE1  . PHE B 2 145 ? 14.36421  10.47724  6.73165   1.000 22.77975  ? 139 PHE L HE1  1 
ATOM   5398 H HE2  . PHE B 2 145 ? 11.35320  13.09524  7.06218   1.000 24.88975  ? 139 PHE L HE2  1 
ATOM   5399 H HZ   . PHE B 2 145 ? 12.09841  10.94186  6.65794   1.000 25.20756  ? 139 PHE L HZ   1 
ATOM   5400 N N    . TYR B 2 146 ? 14.07685  16.01071  10.08770  1.000 19.87637  ? 140 TYR L N    1 
ATOM   5401 C CA   . TYR B 2 146 ? 12.88139  16.25364  10.87792  1.000 21.03656  ? 140 TYR L CA   1 
ATOM   5402 C C    . TYR B 2 146 ? 12.13059  17.39812  10.22270  1.000 22.57816  ? 140 TYR L C    1 
ATOM   5403 O O    . TYR B 2 146 ? 12.77511  18.35081  9.76684   1.000 21.14658  ? 140 TYR L O    1 
ATOM   5404 C CB   . TYR B 2 146 ? 13.21522  16.60594  12.33548  1.000 21.68818  ? 140 TYR L CB   1 
ATOM   5405 C CG   . TYR B 2 146 ? 11.97220  16.66502  13.18447  1.000 21.87073  ? 140 TYR L CG   1 
ATOM   5406 C CD1  . TYR B 2 146 ? 11.19439  17.81576  13.23058  1.000 22.97009  ? 140 TYR L CD1  1 
ATOM   5407 C CD2  . TYR B 2 146 ? 11.53967  15.55391  13.89117  1.000 23.32413  ? 140 TYR L CD2  1 
ATOM   5408 C CE1  . TYR B 2 146 ? 10.03665  17.86400  13.97477  1.000 22.11938  ? 140 TYR L CE1  1 
ATOM   5409 C CE2  . TYR B 2 146 ? 10.38096  15.59441  14.64209  1.000 21.73605  ? 140 TYR L CE2  1 
ATOM   5410 C CZ   . TYR B 2 146 ? 9.63373   16.75150  14.67864  1.000 23.02063  ? 140 TYR L CZ   1 
ATOM   5411 O OH   . TYR B 2 146 ? 8.47667   16.79539  15.42521  1.000 31.32539  ? 140 TYR L OH   1 
ATOM   5412 H H    . TYR B 2 146 ? 14.30153  16.67841  9.59446   1.000 23.85847  ? 140 TYR L H    1 
ATOM   5413 H HA   . TYR B 2 146 ? 12.32506  15.45908  10.88616  1.000 25.25071  ? 140 TYR L HA   1 
ATOM   5414 H HB2  . TYR B 2 146 ? 13.80477  15.92873  12.70251  1.000 26.03264  ? 140 TYR L HB2  1 
ATOM   5415 H HB3  . TYR B 2 146 ? 13.64772  17.47368  12.36505  1.000 26.03264  ? 140 TYR L HB3  1 
ATOM   5416 H HD1  . TYR B 2 146 ? 11.46040  18.56648  12.75041  1.000 27.57094  ? 140 TYR L HD1  1 
ATOM   5417 H HD2  . TYR B 2 146 ? 12.03730  14.76890  13.85930  1.000 27.99579  ? 140 TYR L HD2  1 
ATOM   5418 H HE1  . TYR B 2 146 ? 9.53001   18.64342  14.00171  1.000 26.55009  ? 140 TYR L HE1  1 
ATOM   5419 H HE2  . TYR B 2 146 ? 10.10685  14.84522  15.12010  1.000 26.09009  ? 140 TYR L HE2  1 
ATOM   5420 H HH   . TYR B 2 146 ? 8.11456   17.54958  15.34984  1.000 37.59731  ? 140 TYR L HH   1 
ATOM   5421 N N    . PRO B 2 147 ? 10.78990  17.35071  10.13998  1.000 21.44065  ? 141 PRO L N    1 
ATOM   5422 C CA   . PRO B 2 147 ? 9.89419   16.30005  10.62419  1.000 25.11135  ? 141 PRO L CA   1 
ATOM   5423 C C    . PRO B 2 147 ? 9.85042   15.08331  9.70892   1.000 26.59606  ? 141 PRO L C    1 
ATOM   5424 O O    . PRO B 2 147 ? 10.57733  15.00599  8.71761   1.000 25.00675  ? 141 PRO L O    1 
ATOM   5425 C CB   . PRO B 2 147 ? 8.53823   17.00447  10.66032  1.000 26.42920  ? 141 PRO L CB   1 
ATOM   5426 C CG   . PRO B 2 147 ? 8.61049   17.96445  9.53267   1.000 29.58420  ? 141 PRO L CG   1 
ATOM   5427 C CD   . PRO B 2 147 ? 10.04613  18.40650  9.43014   1.000 24.01653  ? 141 PRO L CD   1 
ATOM   5428 H HA   . PRO B 2 147 ? 10.14488  16.01390  11.51647  1.000 30.14045  ? 141 PRO L HA   1 
ATOM   5429 H HB2  . PRO B 2 147 ? 7.82312   16.36214  10.53021  1.000 31.72187  ? 141 PRO L HB2  1 
ATOM   5430 H HB3  . PRO B 2 147 ? 8.42153   17.46398  11.50656  1.000 31.72187  ? 141 PRO L HB3  1 
ATOM   5431 H HG2  . PRO B 2 147 ? 8.33081   17.52431  8.71477   1.000 35.50788  ? 141 PRO L HG2  1 
ATOM   5432 H HG3  . PRO B 2 147 ? 8.03340   18.72234  9.71561   1.000 35.50788  ? 141 PRO L HG3  1 
ATOM   5433 H HD2  . PRO B 2 147 ? 10.32419  18.45788  8.50227   1.000 28.82667  ? 141 PRO L HD2  1 
ATOM   5434 H HD3  . PRO B 2 147 ? 10.17263  19.26558  9.86244   1.000 28.82667  ? 141 PRO L HD3  1 
ATOM   5435 N N    . ARG B 2 148 ? 8.97097   14.14755  10.06194  1.000 26.31287  ? 142 ARG L N    1 
ATOM   5436 C CA   . ARG B 2 148 ? 8.86323   12.88456  9.34480   1.000 29.61262  ? 142 ARG L CA   1 
ATOM   5437 C C    . ARG B 2 148 ? 8.40066   13.08541  7.90963   1.000 31.96003  ? 142 ARG L C    1 
ATOM   5438 O O    . ARG B 2 148 ? 8.77076   12.30590  7.02248   1.000 26.33210  ? 142 ARG L O    1 
ATOM   5439 C CB   . ARG B 2 148 ? 7.89004   11.97951  10.10069  1.000 36.24084  ? 142 ARG L CB   1 
ATOM   5440 C CG   . ARG B 2 148 ? 7.78653   10.55410  9.60436   1.000 44.77178  ? 142 ARG L CG   1 
ATOM   5441 C CD   . ARG B 2 148 ? 6.70978   9.80569   10.39321  1.000 58.06121  ? 142 ARG L CD   1 
ATOM   5442 N NE   . ARG B 2 148 ? 7.26167   9.06946   11.52669  1.000 59.22635  ? 142 ARG L NE   1 
ATOM   5443 C CZ   . ARG B 2 148 ? 7.29723   7.74524   11.62847  1.000 61.01317  ? 142 ARG L CZ   1 
ATOM   5444 N NH1  . ARG B 2 148 ? 6.76536   6.96276   10.70284  1.000 59.65481  ? 142 ARG L NH1  1 
ATOM   5445 N NH2  . ARG B 2 148 ? 7.87959   7.19179   12.68954  1.000 65.06545  ? 142 ARG L NH2  1 
ATOM   5446 H H    . ARG B 2 148 ? 8.42091   14.22099  10.71893  1.000 31.58227  ? 142 ARG L H    1 
ATOM   5447 H HA   . ARG B 2 148 ? 9.73200   12.45477  9.30700   1.000 35.54198  ? 142 ARG L HA   1 
ATOM   5448 H HB2  . ARG B 2 148 ? 8.17131   11.94002  11.02818  1.000 43.49584  ? 142 ARG L HB2  1 
ATOM   5449 H HB3  . ARG B 2 148 ? 7.00390   12.36921  10.03905  1.000 43.49584  ? 142 ARG L HB3  1 
ATOM   5450 H HG2  . ARG B 2 148 ? 7.54360   10.55113  8.66527   1.000 53.73297  ? 142 ARG L HG2  1 
ATOM   5451 H HG3  . ARG B 2 148 ? 8.63537   10.10149  9.72889   1.000 53.73297  ? 142 ARG L HG3  1 
ATOM   5452 H HD2  . ARG B 2 148 ? 6.06421   10.44432  10.73424  1.000 69.68029  ? 142 ARG L HD2  1 
ATOM   5453 H HD3  . ARG B 2 148 ? 6.27003   9.17049   9.80665   1.000 69.68029  ? 142 ARG L HD3  1 
ATOM   5454 H HE   . ARG B 2 148 ? 7.58826   9.52729   12.17733  1.000 71.07845  ? 142 ARG L HE   1 
ATOM   5455 H HH11 . ARG B 2 148 ? 6.38459   7.30917   10.01392  1.000 71.59261  ? 142 ARG L HH11 1 
ATOM   5456 H HH12 . ARG B 2 148 ? 6.80054   6.10795   10.79035  1.000 71.59261  ? 142 ARG L HH12 1 
ATOM   5457 H HH21 . ARG B 2 148 ? 8.22675   7.69023   13.29834  1.000 78.08537  ? 142 ARG L HH21 1 
ATOM   5458 H HH22 . ARG B 2 148 ? 7.90873   6.33572   12.76638  1.000 78.08537  ? 142 ARG L HH22 1 
ATOM   5459 N N    . GLU B 2 149 ? 7.60491   14.12263  7.66258   1.000 32.42309  ? 143 GLU L N    1 
ATOM   5460 C CA   . GLU B 2 149 ? 6.97716   14.33271  6.36400   1.000 35.38786  ? 143 GLU L CA   1 
ATOM   5461 C C    . GLU B 2 149 ? 7.99826   14.88321  5.37911   1.000 32.69431  ? 143 GLU L C    1 
ATOM   5462 O O    . GLU B 2 149 ? 8.52801   15.98548  5.56313   1.000 29.31850  ? 143 GLU L O    1 
ATOM   5463 C CB   . GLU B 2 149 ? 5.78613   15.28234  6.48987   1.000 38.64049  ? 143 GLU L CB   1 
ATOM   5464 C CG   . GLU B 2 149 ? 4.60345   14.70024  7.26921   1.000 55.87975  ? 143 GLU L CG   1 
ATOM   5465 C CD   . GLU B 2 149 ? 4.90345   14.49953  8.74964   1.000 62.00169  ? 143 GLU L CD   1 
ATOM   5466 O OE1  . GLU B 2 149 ? 5.51571   15.40111  9.36589   1.000 50.61059  ? 143 GLU L OE1  1 
ATOM   5467 O OE2  . GLU B 2 149 ? 4.53449   13.43394  9.29264   1.000 53.33518  ? 143 GLU L OE2  1 
ATOM   5468 H H    . GLU B 2 149 ? 7.41023   14.72846  8.24108   1.000 38.91454  ? 143 GLU L H    1 
ATOM   5469 H HA   . GLU B 2 149 ? 6.65458   13.48188  6.02796   1.000 42.47227  ? 143 GLU L HA   1 
ATOM   5470 H HB2  . GLU B 2 149 ? 6.07628   16.08521  6.95043   1.000 46.37542  ? 143 GLU L HB2  1 
ATOM   5471 H HB3  . GLU B 2 149 ? 5.47154   15.50573  5.59991   1.000 46.37542  ? 143 GLU L HB3  1 
ATOM   5472 H HG2  . GLU B 2 149 ? 3.84983   15.30665  7.19696   1.000 67.06254  ? 143 GLU L HG2  1 
ATOM   5473 H HG3  . GLU B 2 149 ? 4.37210   13.83710  6.89189   1.000 67.06254  ? 143 GLU L HG3  1 
ATOM   5474 N N    . ALA B 2 150 ? 8.26358   14.11636  4.33162   1.000 30.28325  ? 144 ALA L N    1 
ATOM   5475 C CA   . ALA B 2 150 ? 9.23832   14.48594  3.31853   1.000 27.61970  ? 144 ALA L CA   1 
ATOM   5476 C C    . ALA B 2 150 ? 8.79195   13.83080  2.02807   1.000 30.52107  ? 144 ALA L C    1 
ATOM   5477 O O    . ALA B 2 150 ? 8.47986   12.63626  2.02378   1.000 38.28827  ? 144 ALA L O    1 
ATOM   5478 C CB   . ALA B 2 150 ? 10.64646  14.02535  3.69841   1.000 30.17234  ? 144 ALA L CB   1 
ATOM   5479 H H    . ALA B 2 150 ? 7.88336   13.35965  4.18186   1.000 36.34674  ? 144 ALA L H    1 
ATOM   5480 H HA   . ALA B 2 150 ? 9.27194   15.44881  3.20610   1.000 33.15047  ? 144 ALA L HA   1 
ATOM   5481 H HB1  . ALA B 2 150 ? 11.26371  14.28498  2.99664   1.000 36.21364  ? 144 ALA L HB1  1 
ATOM   5482 H HB2  . ALA B 2 150 ? 10.90112  14.44520  4.53494   1.000 36.21364  ? 144 ALA L HB2  1 
ATOM   5483 H HB3  . ALA B 2 150 ? 10.64678  13.06058  3.79897   1.000 36.21364  ? 144 ALA L HB3  1 
ATOM   5484 N N    . LYS B 2 151 ? 8.73079   14.60209  0.95079   1.000 25.86437  ? 145 LYS L N    1 
ATOM   5485 C CA   . LYS B 2 151 ? 8.28111   14.04847  -0.31658  1.000 26.27012  ? 145 LYS L CA   1 
ATOM   5486 C C    . LYS B 2 151 ? 9.49423   13.54972  -1.08729  1.000 27.96555  ? 145 LYS L C    1 
ATOM   5487 O O    . LYS B 2 151 ? 10.44942  14.29925  -1.29429  1.000 22.75559  ? 145 LYS L O    1 
ATOM   5488 C CB   . LYS B 2 151 ? 7.51281   15.08247  -1.13570  1.000 28.70012  ? 145 LYS L CB   1 
ATOM   5489 C CG   . LYS B 2 151 ? 6.61710   14.44361  -2.19812  1.000 40.41933  ? 145 LYS L CG   1 
ATOM   5490 C CD   . LYS B 2 151 ? 6.04592   15.45992  -3.17232  1.000 50.75336  ? 145 LYS L CD   1 
ATOM   5491 C CE   . LYS B 2 151 ? 7.06331   15.83627  -4.24411  1.000 51.03316  ? 145 LYS L CE   1 
ATOM   5492 N NZ   . LYS B 2 151 ? 6.51607   16.81217  -5.22759  1.000 58.57354  ? 145 LYS L NZ   1 
ATOM   5493 H H    . LYS B 2 151 ? 8.94121   15.43569  0.92975   1.000 31.04408  ? 145 LYS L H    1 
ATOM   5494 H HA   . LYS B 2 151 ? 7.67748   13.30661  -0.15477  1.000 31.53098  ? 145 LYS L HA   1 
ATOM   5495 H HB2  . LYS B 2 151 ? 6.95020   15.60253  -0.54080  1.000 34.44698  ? 145 LYS L HB2  1 
ATOM   5496 H HB3  . LYS B 2 151 ? 8.14605   15.66340  -1.58562  1.000 34.44698  ? 145 LYS L HB3  1 
ATOM   5497 H HG2  . LYS B 2 151 ? 7.13694   13.80106  -2.70585  1.000 48.51004  ? 145 LYS L HG2  1 
ATOM   5498 H HG3  . LYS B 2 151 ? 5.87494   13.99810  -1.76037  1.000 48.51004  ? 145 LYS L HG3  1 
ATOM   5499 H HD2  . LYS B 2 151 ? 5.26659   15.08319  -3.61006  1.000 60.91087  ? 145 LYS L HD2  1 
ATOM   5500 H HD3  . LYS B 2 151 ? 5.79899   16.26442  -2.68991  1.000 60.91087  ? 145 LYS L HD3  1 
ATOM   5501 H HE2  . LYS B 2 151 ? 7.83778   16.23788  -3.82008  1.000 61.24663  ? 145 LYS L HE2  1 
ATOM   5502 H HE3  . LYS B 2 151 ? 7.32652   15.03723  -4.72698  1.000 61.24663  ? 145 LYS L HE3  1 
ATOM   5503 H HZ1  . LYS B 2 151 ? 7.13226   17.00503  -5.84014  1.000 70.29509  ? 145 LYS L HZ1  1 
ATOM   5504 H HZ2  . LYS B 2 151 ? 5.80299   16.46767  -5.63372  1.000 70.29509  ? 145 LYS L HZ2  1 
ATOM   5505 H HZ3  . LYS B 2 151 ? 6.27750   17.56204  -4.81182  1.000 70.29509  ? 145 LYS L HZ3  1 
ATOM   5506 N N    . VAL B 2 152 ? 9.45887   12.28565  -1.49614  1.000 20.15437  ? 146 VAL L N    1 
ATOM   5507 C CA   . VAL B 2 152 ? 10.55170  11.66053  -2.23129  1.000 24.05242  ? 146 VAL L CA   1 
ATOM   5508 C C    . VAL B 2 152 ? 9.99936   11.17669  -3.56221  1.000 25.77503  ? 146 VAL L C    1 
ATOM   5509 O O    . VAL B 2 152 ? 9.11348   10.31472  -3.59682  1.000 24.91471  ? 146 VAL L O    1 
ATOM   5510 C CB   . VAL B 2 152 ? 11.18153  10.50203  -1.44572  1.000 21.44234  ? 146 VAL L CB   1 
ATOM   5511 C CG1  . VAL B 2 152 ? 12.37045  9.95034   -2.19992  1.000 23.31442  ? 146 VAL L CG1  1 
ATOM   5512 C CG2  . VAL B 2 152 ? 11.58518  10.96722  -0.06121  1.000 25.99766  ? 146 VAL L CG2  1 
ATOM   5513 H H    . VAL B 2 152 ? 8.79507   11.75727  -1.35549  1.000 24.19207  ? 146 VAL L H    1 
ATOM   5514 H HA   . VAL B 2 152 ? 11.24098  12.32040  -2.40555  1.000 28.86974  ? 146 VAL L HA   1 
ATOM   5515 H HB   . VAL B 2 152 ? 10.53199  9.78887   -1.34377  1.000 25.73764  ? 146 VAL L HB   1 
ATOM   5516 H HG11 . VAL B 2 152 ? 12.85631  9.34152   -1.62184  1.000 27.98413  ? 146 VAL L HG11 1 
ATOM   5517 H HG12 . VAL B 2 152 ? 12.05434  9.47847   -2.98624  1.000 27.98413  ? 146 VAL L HG12 1 
ATOM   5518 H HG13 . VAL B 2 152 ? 12.94556  10.68539  -2.46418  1.000 27.98413  ? 146 VAL L HG13 1 
ATOM   5519 H HG21 . VAL B 2 152 ? 12.06690  10.25268  0.38407   1.000 31.20402  ? 146 VAL L HG21 1 
ATOM   5520 H HG22 . VAL B 2 152 ? 12.15428  11.74836  -0.14395  1.000 31.20402  ? 146 VAL L HG22 1 
ATOM   5521 H HG23 . VAL B 2 152 ? 10.78673  11.19147  0.44187   1.000 31.20402  ? 146 VAL L HG23 1 
ATOM   5522 N N    . SER B 2 153 ? 10.52092  11.73006  -4.64914  1.000 20.26350  ? 147 SER L N    1 
ATOM   5523 C CA   . SER B 2 153 ? 10.04857  11.44307  -5.99417  1.000 19.10193  ? 147 SER L CA   1 
ATOM   5524 C C    . SER B 2 153 ? 11.18137  10.84767  -6.81275  1.000 19.56501  ? 147 SER L C    1 
ATOM   5525 O O    . SER B 2 153 ? 12.32884  11.28492  -6.70356  1.000 20.35394  ? 147 SER L O    1 
ATOM   5526 C CB   . SER B 2 153 ? 9.53520   12.71338  -6.67234  1.000 23.52616  ? 147 SER L CB   1 
ATOM   5527 O OG   . SER B 2 153 ? 8.45518   13.26407  -5.95067  1.000 24.42439  ? 147 SER L OG   1 
ATOM   5528 H H    . SER B 2 153 ? 11.17062  12.29322  -4.63103  1.000 24.32303  ? 147 SER L H    1 
ATOM   5529 H HA   . SER B 2 153 ? 9.32458   10.79856  -5.95752  1.000 22.92915  ? 147 SER L HA   1 
ATOM   5530 H HB2  . SER B 2 153 ? 10.25392  13.36365  -6.71088  1.000 28.23823  ? 147 SER L HB2  1 
ATOM   5531 H HB3  . SER B 2 153 ? 9.23730   12.49461  -7.56917  1.000 28.23823  ? 147 SER L HB3  1 
ATOM   5532 H HG   . SER B 2 153 ? 8.69400   13.43805  -5.16436  1.000 29.31610  ? 147 SER L HG   1 
ATOM   5533 N N    . TRP B 2 154 ? 10.85764  9.85293   -7.63423  1.000 16.46154  ? 148 TRP L N    1 
ATOM   5534 C CA   . TRP B 2 154 ? 11.83828  9.20791   -8.49352  1.000 14.48541  ? 148 TRP L CA   1 
ATOM   5535 C C    . TRP B 2 154 ? 11.67205  9.67534   -9.93352  1.000 17.07706  ? 148 TRP L C    1 
ATOM   5536 O O    . TRP B 2 154 ? 10.55075  9.77072   -10.43939 1.000 17.73570  ? 148 TRP L O    1 
ATOM   5537 C CB   . TRP B 2 154 ? 11.70071  7.69153   -8.42185  1.000 17.69376  ? 148 TRP L CB   1 
ATOM   5538 C CG   . TRP B 2 154 ? 12.28501  7.10968   -7.19317  1.000 17.57752  ? 148 TRP L CG   1 
ATOM   5539 C CD1  . TRP B 2 154 ? 11.62314  6.76345   -6.05160  1.000 22.12992  ? 148 TRP L CD1  1 
ATOM   5540 C CD2  . TRP B 2 154 ? 13.65975  6.80038   -6.97246  1.000 16.11954  ? 148 TRP L CD2  1 
ATOM   5541 N NE1  . TRP B 2 154 ? 12.50634  6.25285   -5.12997  1.000 18.59748  ? 148 TRP L NE1  1 
ATOM   5542 C CE2  . TRP B 2 154 ? 13.76532  6.26925   -5.67147  1.000 19.60296  ? 148 TRP L CE2  1 
ATOM   5543 C CE3  . TRP B 2 154 ? 14.81507  6.92167   -7.74766  1.000 18.88004  ? 148 TRP L CE3  1 
ATOM   5544 C CZ2  . TRP B 2 154 ? 14.98148  5.85133   -5.13341  1.000 21.10077  ? 148 TRP L CZ2  1 
ATOM   5545 C CZ3  . TRP B 2 154 ? 16.02425  6.51452   -7.20843  1.000 21.96558  ? 148 TRP L CZ3  1 
ATOM   5546 C CH2  . TRP B 2 154 ? 16.09724  5.98372   -5.91672  1.000 20.08956  ? 148 TRP L CH2  1 
ATOM   5547 H H    . TRP B 2 154 ? 10.06375  9.53125   -7.71081  1.000 19.76068  ? 148 TRP L H    1 
ATOM   5548 H HA   . TRP B 2 154 ? 12.73041  9.45118   -8.20058  1.000 17.38933  ? 148 TRP L HA   1 
ATOM   5549 H HB2  . TRP B 2 154 ? 10.75887  7.46042   -8.44252  1.000 21.23935  ? 148 TRP L HB2  1 
ATOM   5550 H HB3  . TRP B 2 154 ? 12.15549  7.29870   -9.18327  1.000 21.23935  ? 148 TRP L HB3  1 
ATOM   5551 H HD1  . TRP B 2 154 ? 10.70796  6.85890   -5.91652  1.000 26.56274  ? 148 TRP L HD1  1 
ATOM   5552 H HE1  . TRP B 2 154 ? 12.30256  5.96998   -4.34380  1.000 22.32381  ? 148 TRP L HE1  1 
ATOM   5553 H HE3  . TRP B 2 154 ? 14.77337  7.26911   -8.60931  1.000 22.66288  ? 148 TRP L HE3  1 
ATOM   5554 H HZ2  . TRP B 2 154 ? 15.03327  5.49622   -4.27544  1.000 25.32776  ? 148 TRP L HZ2  1 
ATOM   5555 H HZ3  . TRP B 2 154 ? 16.80065  6.59552   -7.71394  1.000 26.36553  ? 148 TRP L HZ3  1 
ATOM   5556 H HH2  . TRP B 2 154 ? 16.92208  5.71451   -5.58195  1.000 24.11431  ? 148 TRP L HH2  1 
ATOM   5557 N N    . TYR B 2 155 ? 12.79593  9.97025   -10.58450 1.000 18.44521  ? 149 TYR L N    1 
ATOM   5558 C CA   . TYR B 2 155 ? 12.83108  10.34192  -11.99322 1.000 16.46965  ? 149 TYR L CA   1 
ATOM   5559 C C    . TYR B 2 155 ? 13.74257  9.39029   -12.74904 1.000 17.80927  ? 149 TYR L C    1 
ATOM   5560 O O    . TYR B 2 155 ? 14.88257  9.14578   -12.33346 1.000 16.76081  ? 149 TYR L O    1 
ATOM   5561 C CB   . TYR B 2 155 ? 13.32246  11.77766  -12.18550 1.000 14.77362  ? 149 TYR L CB   1 
ATOM   5562 C CG   . TYR B 2 155 ? 12.36210  12.81213  -11.67400 1.000 17.57137  ? 149 TYR L CG   1 
ATOM   5563 C CD1  . TYR B 2 155 ? 12.31901  13.13211  -10.32419 1.000 21.11237  ? 149 TYR L CD1  1 
ATOM   5564 C CD2  . TYR B 2 155 ? 11.49143  13.46750  -12.53226 1.000 22.34105  ? 149 TYR L CD2  1 
ATOM   5565 C CE1  . TYR B 2 155 ? 11.43722  14.07332  -9.84183  1.000 24.38763  ? 149 TYR L CE1  1 
ATOM   5566 C CE2  . TYR B 2 155 ? 10.60020  14.41326  -12.05576 1.000 24.22552  ? 149 TYR L CE2  1 
ATOM   5567 C CZ   . TYR B 2 155 ? 10.57962  14.71172  -10.71066 1.000 28.33271  ? 149 TYR L CZ   1 
ATOM   5568 O OH   . TYR B 2 155 ? 9.70018   15.65552  -10.23111 1.000 36.64141  ? 149 TYR L OH   1 
ATOM   5569 H H    . TYR B 2 155 ? 13.57372  9.96098   -10.21769 1.000 22.14109  ? 149 TYR L H    1 
ATOM   5570 H HA   . TYR B 2 155 ? 11.93388  10.27056  -12.35494 1.000 19.77041  ? 149 TYR L HA   1 
ATOM   5571 H HB2  . TYR B 2 155 ? 14.16007  11.88819  -11.70895 1.000 17.73518  ? 149 TYR L HB2  1 
ATOM   5572 H HB3  . TYR B 2 155 ? 13.45595  11.93850  -13.13271 1.000 17.73518  ? 149 TYR L HB3  1 
ATOM   5573 H HD1  . TYR B 2 155 ? 12.89626  12.70298  -9.73468  1.000 25.34167  ? 149 TYR L HD1  1 
ATOM   5574 H HD2  . TYR B 2 155 ? 11.50674  13.26862  -13.44062 1.000 26.81609  ? 149 TYR L HD2  1 
ATOM   5575 H HE1  . TYR B 2 155 ? 11.42070  14.27692  -8.93454  1.000 29.27199  ? 149 TYR L HE1  1 
ATOM   5576 H HE2  . TYR B 2 155 ? 10.01893  14.84455  -12.63973 1.000 29.07746  ? 149 TYR L HE2  1 
ATOM   5577 H HH   . TYR B 2 155 ? 9.22966   15.95514  -10.85916 1.000 43.97652  ? 149 TYR L HH   1 
ATOM   5578 N N    . VAL B 2 156 ? 13.23469  8.85989   -13.85500 1.000 14.03250  ? 150 VAL L N    1 
ATOM   5579 C CA   . VAL B 2 156 ? 13.98958  8.01158   -14.76680 1.000 14.33387  ? 150 VAL L CA   1 
ATOM   5580 C C    . VAL B 2 156 ? 13.96871  8.69459   -16.12872 1.000 20.62976  ? 150 VAL L C    1 
ATOM   5581 O O    . VAL B 2 156 ? 12.89859  8.85511   -16.72593 1.000 21.85412  ? 150 VAL L O    1 
ATOM   5582 C CB   . VAL B 2 156 ? 13.40000  6.59523   -14.84715 1.000 20.40988  ? 150 VAL L CB   1 
ATOM   5583 C CG1  . VAL B 2 156 ? 14.25205  5.71039   -15.75027 1.000 21.69128  ? 150 VAL L CG1  1 
ATOM   5584 C CG2  . VAL B 2 156 ? 13.26808  5.98527   -13.45047 1.000 19.80556  ? 150 VAL L CG2  1 
ATOM   5585 H H    . VAL B 2 156 ? 12.42192  8.98260   -14.10787 1.000 16.84584  ? 150 VAL L H    1 
ATOM   5586 H HA   . VAL B 2 156 ? 14.90923  7.93577   -14.46781 1.000 17.20748  ? 150 VAL L HA   1 
ATOM   5587 H HB   . VAL B 2 156 ? 12.51169  6.64782   -15.23321 1.000 24.49869  ? 150 VAL L HB   1 
ATOM   5588 H HG11 . VAL B 2 156 ? 13.92492  4.79867   -15.69876 1.000 26.03637  ? 150 VAL L HG11 1 
ATOM   5589 H HG12 . VAL B 2 156 ? 14.18676  6.03422   -16.66228 1.000 26.03637  ? 150 VAL L HG12 1 
ATOM   5590 H HG13 . VAL B 2 156 ? 15.17393  5.74846   -15.45094 1.000 26.03637  ? 150 VAL L HG13 1 
ATOM   5591 H HG21 . VAL B 2 156 ? 12.95035  5.07253   -13.53321 1.000 23.77351  ? 150 VAL L HG21 1 
ATOM   5592 H HG22 . VAL B 2 156 ? 14.13636  5.99536   -13.01817 1.000 23.77351  ? 150 VAL L HG22 1 
ATOM   5593 H HG23 . VAL B 2 156 ? 12.63583  6.51017   -12.93506 1.000 23.77351  ? 150 VAL L HG23 1 
ATOM   5594 N N    . ASP B 2 157 ? 15.14346  9.09629   -16.61425 1.000 21.96934  ? 151 ASP L N    1 
ATOM   5595 C CA   . ASP B 2 157 ? 15.26178  9.88828   -17.84125 1.000 28.87901  ? 151 ASP L CA   1 
ATOM   5596 C C    . ASP B 2 157 ? 14.29443  11.07072  -17.81657 1.000 27.24858  ? 151 ASP L C    1 
ATOM   5597 O O    . ASP B 2 157 ? 13.57627  11.34896  -18.78103 1.000 24.27148  ? 151 ASP L O    1 
ATOM   5598 C CB   . ASP B 2 157 ? 15.04165  9.02108   -19.08039 1.000 26.64434  ? 151 ASP L CB   1 
ATOM   5599 C CG   . ASP B 2 157 ? 16.27145  8.20346   -19.44114 1.000 31.58263  ? 151 ASP L CG   1 
ATOM   5600 O OD1  . ASP B 2 157 ? 17.39060  8.56990   -19.00200 1.000 25.41723  ? 151 ASP L OD1  1 
ATOM   5601 O OD2  . ASP B 2 157 ? 16.11839  7.20136   -20.16871 1.000 28.71670  ? 151 ASP L OD2  1 
ATOM   5602 H H    . ASP B 2 157 ? 15.90005  8.92015   -16.24527 1.000 26.37004  ? 151 ASP L H    1 
ATOM   5603 H HA   . ASP B 2 157 ? 16.16256  10.24490  -17.88946 1.000 34.66165  ? 151 ASP L HA   1 
ATOM   5604 H HB2  . ASP B 2 157 ? 14.31000  8.40685   -18.91213 1.000 31.98005  ? 151 ASP L HB2  1 
ATOM   5605 H HB3  . ASP B 2 157 ? 14.82806  9.59292   -19.83423 1.000 31.98005  ? 151 ASP L HB3  1 
ATOM   5606 N N    . ASN B 2 158 ? 14.28469  11.76341  -16.67667 1.000 24.49481  ? 152 ASN L N    1 
ATOM   5607 C CA   . ASN B 2 158 ? 13.49350  12.95831  -16.39820 1.000 26.15791  ? 152 ASN L CA   1 
ATOM   5608 C C    . ASN B 2 158 ? 11.99823  12.69364  -16.30368 1.000 24.53521  ? 152 ASN L C    1 
ATOM   5609 O O    . ASN B 2 158 ? 11.22826  13.64245  -16.14806 1.000 25.90290  ? 152 ASN L O    1 
ATOM   5610 C CB   . ASN B 2 158 ? 13.74419  14.05758  -17.43547 1.000 29.64678  ? 152 ASN L CB   1 
ATOM   5611 C CG   . ASN B 2 158 ? 15.11401  14.67061  -17.29952 1.000 35.66012  ? 152 ASN L CG   1 
ATOM   5612 O OD1  . ASN B 2 158 ? 15.48356  15.15915  -16.23010 1.000 43.86823  ? 152 ASN L OD1  1 
ATOM   5613 N ND2  . ASN B 2 158 ? 15.89032  14.62760  -18.37403 1.000 46.43442  ? 152 ASN L ND2  1 
ATOM   5614 H H    . ASN B 2 158 ? 14.76666  11.54020  -16.00030 1.000 29.40061  ? 152 ASN L H    1 
ATOM   5615 H HA   . ASN B 2 158 ? 13.77351  13.28608  -15.52926 1.000 31.39633  ? 152 ASN L HA   1 
ATOM   5616 H HB2  . ASN B 2 158 ? 13.67032  13.67798  -18.32505 1.000 35.58297  ? 152 ASN L HB2  1 
ATOM   5617 H HB3  . ASN B 2 158 ? 13.08600  14.76052  -17.31902 1.000 35.58297  ? 152 ASN L HB3  1 
ATOM   5618 H HD21 . ASN B 2 158 ? 16.68126  14.96418  -18.34683 1.000 55.72814  ? 152 ASN L HD21 1 
ATOM   5619 H HD22 . ASN B 2 158 ? 15.60276  14.26314  -19.09796 1.000 55.72814  ? 152 ASN L HD22 1 
ATOM   5620 N N    . ALA B 2 159 ? 11.56319  11.43850  -16.36598 1.000 24.17812  ? 153 ALA L N    1 
ATOM   5621 C CA   . ALA B 2 159 ? 10.15249  11.09481  -16.23533 1.000 16.87345  ? 153 ALA L CA   1 
ATOM   5622 C C    . ALA B 2 159 ? 9.83162   10.79129  -14.77430 1.000 19.72501  ? 153 ALA L C    1 
ATOM   5623 O O    . ALA B 2 159 ? 10.42063  9.88071   -14.17894 1.000 20.29361  ? 153 ALA L O    1 
ATOM   5624 C CB   . ALA B 2 159 ? 9.81754   9.89589   -17.12236 1.000 21.85054  ? 153 ALA L CB   1 
ATOM   5625 H H    . ALA B 2 159 ? 12.07492  10.75770  -16.48529 1.000 29.02058  ? 153 ALA L H    1 
ATOM   5626 H HA   . ALA B 2 159 ? 9.60818   11.84855  -16.51189 1.000 20.25497  ? 153 ALA L HA   1 
ATOM   5627 H HB1  . ALA B 2 159 ? 8.88191   9.66819   -17.00549 1.000 26.22748  ? 153 ALA L HB1  1 
ATOM   5628 H HB2  . ALA B 2 159 ? 9.98772   10.13059  -18.04803 1.000 26.22748  ? 153 ALA L HB2  1 
ATOM   5629 H HB3  . ALA B 2 159 ? 10.37537  9.14580   -16.86337 1.000 26.22748  ? 153 ALA L HB3  1 
ATOM   5630 N N    . LEU B 2 160 ? 8.90346   11.55416  -14.19970 1.000 16.81646  ? 154 LEU L N    1 
ATOM   5631 C CA   . LEU B 2 160 ? 8.46582   11.29971  -12.83191 1.000 21.16999  ? 154 LEU L CA   1 
ATOM   5632 C C    . LEU B 2 160 ? 7.76046   9.95311   -12.74812 1.000 23.95466  ? 154 LEU L C    1 
ATOM   5633 O O    . LEU B 2 160 ? 6.84834   9.66558   -13.53029 1.000 20.06001  ? 154 LEU L O    1 
ATOM   5634 C CB   . LEU B 2 160 ? 7.53746   12.41234  -12.35125 1.000 19.68431  ? 154 LEU L CB   1 
ATOM   5635 C CG   . LEU B 2 160 ? 6.85484   12.20392  -10.99944 1.000 22.43709  ? 154 LEU L CG   1 
ATOM   5636 C CD1  . LEU B 2 160 ? 7.87522   12.02644  -9.87534  1.000 24.38338  ? 154 LEU L CD1  1 
ATOM   5637 C CD2  . LEU B 2 160 ? 5.92293   13.37427  -10.69710 1.000 23.75621  ? 154 LEU L CD2  1 
ATOM   5638 H H    . LEU B 2 160 ? 8.51453   12.22093  -14.57884 1.000 20.18659  ? 154 LEU L H    1 
ATOM   5639 H HA   . LEU B 2 160 ? 9.23984   11.27978  -12.24762 1.000 25.41082  ? 154 LEU L HA   1 
ATOM   5640 H HB2  . LEU B 2 160 ? 8.05791   13.22809  -12.28361 1.000 23.62800  ? 154 LEU L HB2  1 
ATOM   5641 H HB3  . LEU B 2 160 ? 6.83429   12.52114  -13.01050 1.000 23.62800  ? 154 LEU L HB3  1 
ATOM   5642 H HG   . LEU B 2 160 ? 6.32985   11.38932  -11.04098 1.000 26.93134  ? 154 LEU L HG   1 
ATOM   5643 H HD11 . LEU B 2 160 ? 7.40387   11.93483  -9.03253  1.000 29.26689  ? 154 LEU L HD11 1 
ATOM   5644 H HD12 . LEU B 2 160 ? 8.40073   11.22978  -10.04873 1.000 29.26689  ? 154 LEU L HD12 1 
ATOM   5645 H HD13 . LEU B 2 160 ? 8.45353   12.80472  -9.84801  1.000 29.26689  ? 154 LEU L HD13 1 
ATOM   5646 H HD21 . LEU B 2 160 ? 5.49421   13.22337  -9.84016  1.000 28.51428  ? 154 LEU L HD21 1 
ATOM   5647 H HD22 . LEU B 2 160 ? 6.44300   14.19252  -10.66724 1.000 28.51428  ? 154 LEU L HD22 1 
ATOM   5648 H HD23 . LEU B 2 160 ? 5.25312   13.43338  -11.39621 1.000 28.51428  ? 154 LEU L HD23 1 
ATOM   5649 N N    . GLN B 2 161 ? 8.17615   9.14093   -11.78240 1.000 19.85259  ? 155 GLN L N    1 
ATOM   5650 C CA   . GLN B 2 161 ? 7.67998   7.78727   -11.60736 1.000 19.37803  ? 155 GLN L CA   1 
ATOM   5651 C C    . GLN B 2 161 ? 6.52589   7.74233   -10.61388 1.000 26.00216  ? 155 GLN L C    1 
ATOM   5652 O O    . GLN B 2 161 ? 6.36693   8.61825   -9.76065  1.000 25.69769  ? 155 GLN L O    1 
ATOM   5653 C CB   . GLN B 2 161 ? 8.79957   6.87507   -11.11389 1.000 18.30847  ? 155 GLN L CB   1 
ATOM   5654 C CG   . GLN B 2 161 ? 9.95458   6.77920   -12.06691 1.000 18.72007  ? 155 GLN L CG   1 
ATOM   5655 C CD   . GLN B 2 161 ? 9.55915   6.10207   -13.35443 1.000 22.90770  ? 155 GLN L CD   1 
ATOM   5656 O OE1  . GLN B 2 161 ? 9.36580   4.88771   -13.39199 1.000 22.56840  ? 155 GLN L OE1  1 
ATOM   5657 N NE2  . GLN B 2 161 ? 9.42368   6.88491   -14.41829 1.000 23.19819  ? 155 GLN L NE2  1 
ATOM   5658 H H    . GLN B 2 161 ? 8.76600   9.36107   -11.19656 1.000 23.82995  ? 155 GLN L H    1 
ATOM   5659 H HA   . GLN B 2 161 ? 7.35544   7.46335   -12.46214 1.000 23.26047  ? 155 GLN L HA   1 
ATOM   5660 H HB2  . GLN B 2 161 ? 9.13623   7.21987   -10.27206 1.000 21.97700  ? 155 GLN L HB2  1 
ATOM   5661 H HB3  . GLN B 2 161 ? 8.44297   5.98186   -10.98771 1.000 21.97700  ? 155 GLN L HB3  1 
ATOM   5662 H HG2  . GLN B 2 161 ? 10.27139  7.67161   -12.27698 1.000 22.47092  ? 155 GLN L HG2  1 
ATOM   5663 H HG3  . GLN B 2 161 ? 10.66592  6.26253   -11.65709 1.000 22.47092  ? 155 GLN L HG3  1 
ATOM   5664 H HE21 . GLN B 2 161 ? 9.56023   7.73121   -14.34960 1.000 27.84466  ? 155 GLN L HE21 1 
ATOM   5665 H HE22 . GLN B 2 161 ? 9.19940   6.54564   -15.17605 1.000 27.84466  ? 155 GLN L HE22 1 
ATOM   5666 N N    . SER B 2 162 ? 5.73291   6.67933   -10.71814 1.000 20.96178  ? 156 SER L N    1 
ATOM   5667 C CA   . SER B 2 162 ? 4.62867   6.44667   -9.80130  1.000 24.42760  ? 156 SER L CA   1 
ATOM   5668 C C    . SER B 2 162 ? 4.37775   4.95069   -9.70496  1.000 26.59338  ? 156 SER L C    1 
ATOM   5669 O O    . SER B 2 162 ? 4.33172   4.26110   -10.72679 1.000 27.95485  ? 156 SER L O    1 
ATOM   5670 C CB   . SER B 2 162 ? 3.36470   7.17586   -10.27301 1.000 31.16197  ? 156 SER L CB   1 
ATOM   5671 O OG   . SER B 2 162 ? 2.20878   6.64182   -9.65914  1.000 43.45046  ? 156 SER L OG   1 
ATOM   5672 H H    . SER B 2 162 ? 5.81737   6.07161   -11.32074 1.000 25.16096  ? 156 SER L H    1 
ATOM   5673 H HA   . SER B 2 162 ? 4.85942   6.77277   -8.91738  1.000 29.31995  ? 156 SER L HA   1 
ATOM   5674 H HB2  . SER B 2 162 ? 3.43843   8.11494   -10.04151 1.000 37.40120  ? 156 SER L HB2  1 
ATOM   5675 H HB3  . SER B 2 162 ? 3.28460   7.07651   -11.23458 1.000 37.40120  ? 156 SER L HB3  1 
ATOM   5676 H HG   . SER B 2 162 ? 1.52224   7.01966   -9.96163  1.000 52.14739  ? 156 SER L HG   1 
ATOM   5677 N N    . GLY B 2 163 ? 4.23420   4.45336   -8.47691  1.000 26.64664  ? 157 GLY L N    1 
ATOM   5678 C CA   . GLY B 2 163 ? 3.78229   3.10023   -8.24140  1.000 25.38384  ? 157 GLY L CA   1 
ATOM   5679 C C    . GLY B 2 163 ? 4.86492   2.05325   -8.08398  1.000 29.31205  ? 157 GLY L C    1 
ATOM   5680 O O    . GLY B 2 163 ? 4.55167   0.92486   -7.68198  1.000 27.71736  ? 157 GLY L O    1 
ATOM   5681 H H    . GLY B 2 163 ? 4.39721   4.89430   -7.75677  1.000 31.98280  ? 157 GLY L H    1 
ATOM   5682 H HA2  . GLY B 2 163 ? 3.25083   3.09250   -7.42998  1.000 30.46744  ? 157 GLY L HA2  1 
ATOM   5683 H HA3  . GLY B 2 163 ? 3.22386   2.83047   -8.98724  1.000 30.46744  ? 157 GLY L HA3  1 
ATOM   5684 N N    . ASN B 2 164 ? 6.12562   2.37558   -8.37953  1.000 22.68594  ? 158 ASN L N    1 
ATOM   5685 C CA   . ASN B 2 164 ? 7.18611   1.37682   -8.40096  1.000 23.49072  ? 158 ASN L CA   1 
ATOM   5686 C C    . ASN B 2 164 ? 8.23699   1.60082   -7.31559  1.000 25.47989  ? 158 ASN L C    1 
ATOM   5687 O O    . ASN B 2 164 ? 9.36313   1.10978   -7.44261  1.000 20.27414  ? 158 ASN L O    1 
ATOM   5688 C CB   . ASN B 2 164 ? 7.84758   1.34219   -9.78098  1.000 20.99997  ? 158 ASN L CB   1 
ATOM   5689 C CG   . ASN B 2 164 ? 8.20366   2.72015   -10.29253 1.000 20.61326  ? 158 ASN L CG   1 
ATOM   5690 O OD1  . ASN B 2 164 ? 8.03394   3.72326   -9.59400  1.000 24.18724  ? 158 ASN L OD1  1 
ATOM   5691 N ND2  . ASN B 2 164 ? 8.69179   2.78031   -11.52120 1.000 24.04592  ? 158 ASN L ND2  1 
ATOM   5692 H H    . ASN B 2 164 ? 6.38877   3.17149   -8.57156  1.000 27.22996  ? 158 ASN L H    1 
ATOM   5693 H HA   . ASN B 2 164 ? 6.78487   0.50979   -8.23312  1.000 28.19570  ? 158 ASN L HA   1 
ATOM   5694 H HB2  . ASN B 2 164 ? 8.66432   0.82167   -9.72727  1.000 25.20679  ? 158 ASN L HB2  1 
ATOM   5695 H HB3  . ASN B 2 164 ? 7.23608   0.93554   -10.41471 1.000 25.20679  ? 158 ASN L HB3  1 
ATOM   5696 H HD21 . ASN B 2 164 ? 8.91044   3.53978   -11.86032 1.000 28.86193  ? 158 ASN L HD21 1 
ATOM   5697 H HD22 . ASN B 2 164 ? 8.79033   2.05994   -11.98050 1.000 28.86193  ? 158 ASN L HD22 1 
ATOM   5698 N N    . SER B 2 165 ? 7.89124   2.30893   -6.24078  1.000 23.49159  ? 159 SER L N    1 
ATOM   5699 C CA   . SER B 2 165 ? 8.81954   2.52450   -5.13904  1.000 19.90753  ? 159 SER L CA   1 
ATOM   5700 C C    . SER B 2 165 ? 8.12135   2.27989   -3.80769  1.000 22.74550  ? 159 SER L C    1 
ATOM   5701 O O    . SER B 2 165 ? 6.89754   2.37379   -3.69079  1.000 24.43416  ? 159 SER L O    1 
ATOM   5702 C CB   . SER B 2 165 ? 9.41135   3.94335   -5.16623  1.000 22.89491  ? 159 SER L CB   1 
ATOM   5703 O OG   . SER B 2 165 ? 8.40665   4.92420   -4.99558  1.000 22.98710  ? 159 SER L OG   1 
ATOM   5704 H H    . SER B 2 165 ? 7.12093   2.67466   -6.12911  1.000 28.19674  ? 159 SER L H    1 
ATOM   5705 H HA   . SER B 2 165 ? 9.54700   1.88721   -5.21370  1.000 23.89587  ? 159 SER L HA   1 
ATOM   5706 H HB2  . SER B 2 165 ? 10.05726  4.02761   -4.44747  1.000 27.48073  ? 159 SER L HB2  1 
ATOM   5707 H HB3  . SER B 2 165 ? 9.84634   4.08542   -6.02151  1.000 27.48073  ? 159 SER L HB3  1 
ATOM   5708 H HG   . SER B 2 165 ? 8.74813   5.69144   -5.01374  1.000 27.59136  ? 159 SER L HG   1 
ATOM   5709 N N    . GLN B 2 166 ? 8.92857   1.95970   -2.80059  1.000 21.10951  ? 160 GLN L N    1 
ATOM   5710 C CA   . GLN B 2 166 ? 8.44926   1.73780   -1.44299  1.000 19.88136  ? 160 GLN L CA   1 
ATOM   5711 C C    . GLN B 2 166 ? 9.34253   2.47488   -0.45814  1.000 22.33226  ? 160 GLN L C    1 
ATOM   5712 O O    . GLN B 2 166 ? 10.55944  2.54010   -0.64578  1.000 21.31109  ? 160 GLN L O    1 
ATOM   5713 C CB   . GLN B 2 166 ? 8.42648   0.25243   -1.08857  1.000 25.62578  ? 160 GLN L CB   1 
ATOM   5714 C CG   . GLN B 2 166 ? 7.32762   -0.54654  -1.77887  1.000 32.80955  ? 160 GLN L CG   1 
ATOM   5715 C CD   . GLN B 2 166 ? 7.25053   -1.97854  -1.27112  1.000 36.75684  ? 160 GLN L CD   1 
ATOM   5716 O OE1  . GLN B 2 166 ? 8.15200   -2.77897  -1.51323  1.000 39.19960  ? 160 GLN L OE1  1 
ATOM   5717 N NE2  . GLN B 2 166 ? 6.17563   -2.30219  -0.55146  1.000 27.09700  ? 160 GLN L NE2  1 
ATOM   5718 H H    . GLN B 2 166 ? 9.77920   1.86316   -2.88254  1.000 25.33825  ? 160 GLN L H    1 
ATOM   5719 H HA   . GLN B 2 166 ? 7.54719   2.08605   -1.36625  1.000 23.86447  ? 160 GLN L HA   1 
ATOM   5720 H HB2  . GLN B 2 166 ? 9.27681   -0.13876  -1.34315  1.000 30.75777  ? 160 GLN L HB2  1 
ATOM   5721 H HB3  . GLN B 2 166 ? 8.29452   0.16541   -0.13154  1.000 30.75777  ? 160 GLN L HB3  1 
ATOM   5722 H HG2  . GLN B 2 166 ? 6.47224   -0.12055  -1.61228  1.000 39.37830  ? 160 GLN L HG2  1 
ATOM   5723 H HG3  . GLN B 2 166 ? 7.50488   -0.57323  -2.73217  1.000 39.37830  ? 160 GLN L HG3  1 
ATOM   5724 H HE21 . GLN B 2 166 ? 5.56918   -1.71271  -0.39543  1.000 32.52323  ? 160 GLN L HE21 1 
ATOM   5725 H HE22 . GLN B 2 166 ? 6.08882   -3.10039  -0.24336  1.000 32.52323  ? 160 GLN L HE22 1 
ATOM   5726 N N    . GLU B 2 167 ? 8.74134   3.00883   0.60107   1.000 19.30671  ? 161 GLU L N    1 
ATOM   5727 C CA   . GLU B 2 167 ? 9.47144   3.75907   1.60953   1.000 22.96001  ? 161 GLU L CA   1 
ATOM   5728 C C    . GLU B 2 167 ? 9.48191   3.01737   2.94056   1.000 22.47491  ? 161 GLU L C    1 
ATOM   5729 O O    . GLU B 2 167 ? 8.61882   2.18532   3.23370   1.000 23.91602  ? 161 GLU L O    1 
ATOM   5730 C CB   . GLU B 2 167 ? 8.87228   5.15818   1.80417   1.000 21.54116  ? 161 GLU L CB   1 
ATOM   5731 C CG   . GLU B 2 167 ? 9.15944   6.11167   0.66702   1.000 31.06378  ? 161 GLU L CG   1 
ATOM   5732 C CD   . GLU B 2 167 ? 8.50925   7.47164   0.86240   1.000 41.63456  ? 161 GLU L CD   1 
ATOM   5733 O OE1  . GLU B 2 167 ? 7.94382   7.71438   1.95151   1.000 36.59355  ? 161 GLU L OE1  1 
ATOM   5734 O OE2  . GLU B 2 167 ? 8.56117   8.29512   -0.07837  1.000 40.86783  ? 161 GLU L OE2  1 
ATOM   5735 H H    . GLU B 2 167 ? 7.89781   2.94713   0.75682   1.000 23.17488  ? 161 GLU L H    1 
ATOM   5736 H HA   . GLU B 2 167 ? 10.39020  3.85695   1.31422   1.000 27.55885  ? 161 GLU L HA   1 
ATOM   5737 H HB2  . GLU B 2 167 ? 7.90914   5.07575   1.88452   1.000 25.85622  ? 161 GLU L HB2  1 
ATOM   5738 H HB3  . GLU B 2 167 ? 9.24089   5.54459   2.61393   1.000 25.85622  ? 161 GLU L HB3  1 
ATOM   5739 H HG2  . GLU B 2 167 ? 10.11799  6.24424   0.59994   1.000 37.28337  ? 161 GLU L HG2  1 
ATOM   5740 H HG3  . GLU B 2 167 ? 8.81852   5.73184   -0.15785  1.000 37.28337  ? 161 GLU L HG3  1 
ATOM   5741 N N    . SER B 2 168 ? 10.49489  3.32770   3.74020   1.000 19.34699  ? 162 SER L N    1 
ATOM   5742 C CA   . SER B 2 168 ? 10.60351  2.81719   5.09962   1.000 20.64125  ? 162 SER L CA   1 
ATOM   5743 C C    . SER B 2 168 ? 11.28679  3.89211   5.92896   1.000 22.47533  ? 162 SER L C    1 
ATOM   5744 O O    . SER B 2 168 ? 12.17129  4.58848   5.43041   1.000 19.09254  ? 162 SER L O    1 
ATOM   5745 C CB   . SER B 2 168 ? 11.38632  1.50032   5.13991   1.000 24.71935  ? 162 SER L CB   1 
ATOM   5746 O OG   . SER B 2 168 ? 11.43796  0.97087   6.45207   1.000 25.52009  ? 162 SER L OG   1 
ATOM   5747 H H    . SER B 2 168 ? 11.14528  3.84280   3.51378   1.000 23.22322  ? 162 SER L H    1 
ATOM   5748 H HA   . SER B 2 168 ? 9.72872   2.63865   5.47878   1.000 24.77634  ? 162 SER L HA   1 
ATOM   5749 H HB2  . SER B 2 168 ? 10.94931  0.85775   4.55937   1.000 29.67006  ? 162 SER L HB2  1 
ATOM   5750 H HB3  . SER B 2 168 ? 12.29143  1.66391   4.83183   1.000 29.67006  ? 162 SER L HB3  1 
ATOM   5751 H HG   . SER B 2 168 ? 11.88705  0.26102   6.45799   1.000 30.63094  ? 162 SER L HG   1 
ATOM   5752 N N    . VAL B 2 169 ? 10.85725  4.04736   7.17993   1.000 20.36625  ? 163 VAL L N    1 
ATOM   5753 C CA   . VAL B 2 169 ? 11.37006  5.09537   8.05630   1.000 20.10882  ? 163 VAL L CA   1 
ATOM   5754 C C    . VAL B 2 169 ? 11.79896  4.46789   9.37297   1.000 22.99995  ? 163 VAL L C    1 
ATOM   5755 O O    . VAL B 2 169 ? 11.12703  3.57194   9.89652   1.000 21.22263  ? 163 VAL L O    1 
ATOM   5756 C CB   . VAL B 2 169 ? 10.31805  6.20088   8.29495   1.000 28.27160  ? 163 VAL L CB   1 
ATOM   5757 C CG1  . VAL B 2 169 ? 9.17055   5.67031   9.14718   1.000 34.39617  ? 163 VAL L CG1  1 
ATOM   5758 C CG2  . VAL B 2 169 ? 10.95216  7.42328   8.93875   1.000 25.66843  ? 163 VAL L CG2  1 
ATOM   5759 H H    . VAL B 2 169 ? 10.26014  3.54955   7.54768   1.000 24.44633  ? 163 VAL L H    1 
ATOM   5760 H HA   . VAL B 2 169 ? 12.15090  5.49965   7.64675   1.000 24.13741  ? 163 VAL L HA   1 
ATOM   5761 H HB   . VAL B 2 169 ? 9.95515   6.47490   7.43815   1.000 33.93275  ? 163 VAL L HB   1 
ATOM   5762 H HG11 . VAL B 2 169 ? 8.37365   6.19212   8.96401   1.000 41.28223  ? 163 VAL L HG11 1 
ATOM   5763 H HG12 . VAL B 2 169 ? 9.01509   4.73940   8.92327   1.000 41.28223  ? 163 VAL L HG12 1 
ATOM   5764 H HG13 . VAL B 2 169 ? 9.40988   5.74971   10.08383  1.000 41.28223  ? 163 VAL L HG13 1 
ATOM   5765 H HG21 . VAL B 2 169 ? 10.27249  8.10462   9.06018   1.000 30.80895  ? 163 VAL L HG21 1 
ATOM   5766 H HG22 . VAL B 2 169 ? 11.32426  7.17039   9.79810   1.000 30.80895  ? 163 VAL L HG22 1 
ATOM   5767 H HG23 . VAL B 2 169 ? 11.65491  7.75669   8.35919   1.000 30.80895  ? 163 VAL L HG23 1 
ATOM   5768 N N    . THR B 2 170 ? 12.92731  4.92598   9.89935   1.000 22.89998  ? 164 THR L N    1 
ATOM   5769 C CA   . THR B 2 170 ? 13.33420  4.49256   11.22081  1.000 24.61157  ? 164 THR L CA   1 
ATOM   5770 C C    . THR B 2 170 ? 12.45403  5.14912   12.28186  1.000 28.70234  ? 164 THR L C    1 
ATOM   5771 O O    . THR B 2 170 ? 11.62464  6.02174   12.00002  1.000 20.68071  ? 164 THR L O    1 
ATOM   5772 C CB   . THR B 2 170 ? 14.79770  4.83919   11.48299  1.000 25.94263  ? 164 THR L CB   1 
ATOM   5773 O OG1  . THR B 2 170 ? 14.99786  6.24880   11.30620  1.000 27.49322  ? 164 THR L OG1  1 
ATOM   5774 C CG2  . THR B 2 170 ? 15.70656  4.06708   10.54150  1.000 25.77458  ? 164 THR L CG2  1 
ATOM   5775 H H    . THR B 2 170 ? 13.46333  5.47861   9.51609   1.000 27.48681  ? 164 THR L H    1 
ATOM   5776 H HA   . THR B 2 170 ? 13.23664  3.52922   11.27883  1.000 29.54072  ? 164 THR L HA   1 
ATOM   5777 H HB   . THR B 2 170 ? 15.03181  4.59636   12.39245  1.000 31.13799  ? 164 THR L HB   1 
ATOM   5778 H HG1  . THR B 2 170 ? 14.52145  6.67700   11.84960  1.000 32.99870  ? 164 THR L HG1  1 
ATOM   5779 H HG21 . THR B 2 170 ? 16.63404  4.28757   10.72060  1.000 30.93632  ? 164 THR L HG21 1 
ATOM   5780 H HG22 . THR B 2 170 ? 15.58000  3.11346   10.66598  1.000 30.93632  ? 164 THR L HG22 1 
ATOM   5781 H HG23 . THR B 2 170 ? 15.50100  4.29443   9.62120   1.000 30.93632  ? 164 THR L HG23 1 
ATOM   5782 N N    . GLU B 2 171 ? 12.63461  4.69765   13.51615  1.000 30.55056  ? 165 GLU L N    1 
ATOM   5783 C CA   . GLU B 2 171 ? 12.09621  5.39191   14.67200  1.000 36.00209  ? 165 GLU L CA   1 
ATOM   5784 C C    . GLU B 2 171 ? 12.98990  6.58062   15.01166  1.000 30.00315  ? 165 GLU L C    1 
ATOM   5785 O O    . GLU B 2 171 ? 14.14806  6.66176   14.58640  1.000 30.78204  ? 165 GLU L O    1 
ATOM   5786 C CB   . GLU B 2 171 ? 11.99264  4.43845   15.86459  1.000 45.70062  ? 165 GLU L CB   1 
ATOM   5787 C CG   . GLU B 2 171 ? 13.33990  3.87502   16.32994  1.000 55.13120  ? 165 GLU L CG   1 
ATOM   5788 C CD   . GLU B 2 171 ? 13.22614  2.48121   16.92767  1.000 71.71542  ? 165 GLU L CD   1 
ATOM   5789 O OE1  . GLU B 2 171 ? 12.86970  1.54071   16.18449  1.000 79.97824  ? 165 GLU L OE1  1 
ATOM   5790 O OE2  . GLU B 2 171 ? 13.48843  2.32605   18.13990  1.000 62.86043  ? 165 GLU L OE2  1 
ATOM   5791 H H    . GLU B 2 171 ? 13.07078  3.98267   13.71151  1.000 36.66751  ? 165 GLU L H    1 
ATOM   5792 H HA   . GLU B 2 171 ? 11.20346  5.72119   14.48365  1.000 43.20934  ? 165 GLU L HA   1 
ATOM   5793 H HB2  . GLU B 2 171 ? 11.59856  4.91602   16.61127  1.000 54.84758  ? 165 GLU L HB2  1 
ATOM   5794 H HB3  . GLU B 2 171 ? 11.42934  3.68905   15.61562  1.000 54.84758  ? 165 GLU L HB3  1 
ATOM   5795 H HG2  . GLU B 2 171 ? 13.94063  3.82626   15.56991  1.000 66.16427  ? 165 GLU L HG2  1 
ATOM   5796 H HG3  . GLU B 2 171 ? 13.70971  4.46184   17.00801  1.000 66.16427  ? 165 GLU L HG3  1 
ATOM   5797 N N    . GLN B 2 172 ? 12.43760  7.51624   15.78137  1.000 25.80355  ? 166 GLN L N    1 
ATOM   5798 C CA   . GLN B 2 172 ? 13.20007  8.69754   16.16082  1.000 27.49678  ? 166 GLN L CA   1 
ATOM   5799 C C    . GLN B 2 172 ? 14.50635  8.31008   16.83418  1.000 26.69015  ? 166 GLN L C    1 
ATOM   5800 O O    . GLN B 2 172 ? 14.56135  7.37099   17.63244  1.000 31.17084  ? 166 GLN L O    1 
ATOM   5801 C CB   . GLN B 2 172 ? 12.39181  9.58447   17.10721  1.000 26.30850  ? 166 GLN L CB   1 
ATOM   5802 C CG   . GLN B 2 172 ? 11.24519  10.28653  16.45716  1.000 23.99273  ? 166 GLN L CG   1 
ATOM   5803 C CD   . GLN B 2 172 ? 10.67740  11.37645  17.33616  1.000 25.94753  ? 166 GLN L CD   1 
ATOM   5804 O OE1  . GLN B 2 172 ? 9.86353   11.11431  18.22187  1.000 25.01763  ? 166 GLN L OE1  1 
ATOM   5805 N NE2  . GLN B 2 172 ? 11.11347  12.61101  17.10379  1.000 21.31942  ? 166 GLN L NE2  1 
ATOM   5806 H H    . GLN B 2 172 ? 11.63582  7.48974   16.09127  1.000 30.97110  ? 166 GLN L H    1 
ATOM   5807 H HA   . GLN B 2 172 ? 13.39943  9.20229   15.35684  1.000 33.00297  ? 166 GLN L HA   1 
ATOM   5808 H HB2  . GLN B 2 172 ? 12.03329  9.03222   17.81952  1.000 31.57704  ? 166 GLN L HB2  1 
ATOM   5809 H HB3  . GLN B 2 172 ? 12.98037  10.26135  17.47645  1.000 31.57704  ? 166 GLN L HB3  1 
ATOM   5810 H HG2  . GLN B 2 172 ? 11.54705  10.69138  15.62898  1.000 28.79811  ? 166 GLN L HG2  1 
ATOM   5811 H HG3  . GLN B 2 172 ? 10.54021  9.64553   16.27543  1.000 28.79811  ? 166 GLN L HG3  1 
ATOM   5812 H HE21 . GLN B 2 172 ? 11.68827  12.75378  16.48024  1.000 25.59014  ? 166 GLN L HE21 1 
ATOM   5813 H HE22 . GLN B 2 172 ? 10.82068  13.26667  17.57707  1.000 25.59014  ? 166 GLN L HE22 1 
ATOM   5814 N N    . ASP B 2 173 ? 15.56106  9.04924   16.51295  1.000 25.29516  ? 167 ASP L N    1 
ATOM   5815 C CA   . ASP B 2 173 ? 16.81187  8.90698   17.23792  1.000 29.78386  ? 167 ASP L CA   1 
ATOM   5816 C C    . ASP B 2 173 ? 16.57229  9.25936   18.70056  1.000 34.90896  ? 167 ASP L C    1 
ATOM   5817 O O    . ASP B 2 173 ? 15.85641  10.21375  19.01291  1.000 31.35534  ? 167 ASP L O    1 
ATOM   5818 C CB   . ASP B 2 173 ? 17.87403  9.81353   16.62241  1.000 34.34986  ? 167 ASP L CB   1 
ATOM   5819 C CG   . ASP B 2 173 ? 19.26330  9.53102   17.15185  1.000 38.94982  ? 167 ASP L CG   1 
ATOM   5820 O OD1  . ASP B 2 173 ? 19.86089  8.51527   16.73576  1.000 53.06799  ? 167 ASP L OD1  1 
ATOM   5821 O OD2  . ASP B 2 173 ? 19.75914  10.32896  17.97696  1.000 34.61647  ? 167 ASP L OD2  1 
ATOM   5822 H H    . ASP B 2 173 ? 15.57703  9.63546   15.88392  1.000 30.36103  ? 167 ASP L H    1 
ATOM   5823 H HA   . ASP B 2 173 ? 17.14454  7.99732   17.18544  1.000 35.74747  ? 167 ASP L HA   1 
ATOM   5824 H HB2  . ASP B 2 173 ? 17.88611  9.67925   15.66183  1.000 41.22666  ? 167 ASP L HB2  1 
ATOM   5825 H HB3  . ASP B 2 173 ? 17.65770  10.73701  16.82560  1.000 41.22666  ? 167 ASP L HB3  1 
ATOM   5826 N N    . SER B 2 174 ? 17.14676  8.46575   19.60444  1.000 39.82730  ? 168 SER L N    1 
ATOM   5827 C CA   . SER B 2 174 ? 16.90261  8.66631   21.02905  1.000 44.13474  ? 168 SER L CA   1 
ATOM   5828 C C    . SER B 2 174 ? 17.74303  9.78641   21.63180  1.000 33.66518  ? 168 SER L C    1 
ATOM   5829 O O    . SER B 2 174 ? 17.53389  10.13032  22.79937  1.000 32.30082  ? 168 SER L O    1 
ATOM   5830 C CB   . SER B 2 174 ? 17.14839  7.36071   21.79086  1.000 41.34501  ? 168 SER L CB   1 
ATOM   5831 O OG   . SER B 2 174 ? 18.29549  6.69518   21.29786  1.000 48.47036  ? 168 SER L OG   1 
ATOM   5832 H H    . SER B 2 174 ? 17.67495  7.81292   19.41890  1.000 47.79959  ? 168 SER L H    1 
ATOM   5833 H HA   . SER B 2 174 ? 15.97146  8.90901   21.15133  1.000 52.96852  ? 168 SER L HA   1 
ATOM   5834 H HB2  . SER B 2 174 ? 17.28104  7.56387   22.73002  1.000 49.62084  ? 168 SER L HB2  1 
ATOM   5835 H HB3  . SER B 2 174 ? 16.37729  6.78235   21.68223  1.000 49.62084  ? 168 SER L HB3  1 
ATOM   5836 H HG   . SER B 2 174 ? 18.39214  5.95942   21.69146  1.000 58.17127  ? 168 SER L HG   1 
ATOM   5837 N N    . LYS B 2 175 ? 18.67289  10.36413  20.87638  1.000 30.32954  ? 169 LYS L N    1 
ATOM   5838 C CA   . LYS B 2 175 ? 19.38778  11.56709  21.28560  1.000 36.89159  ? 169 LYS L CA   1 
ATOM   5839 C C    . LYS B 2 175 ? 19.05107  12.77074  20.41983  1.000 37.33587  ? 169 LYS L C    1 
ATOM   5840 O O    . LYS B 2 175 ? 18.92329  13.88451  20.94108  1.000 34.30331  ? 169 LYS L O    1 
ATOM   5841 C CB   . LYS B 2 175 ? 20.90162  11.31790  21.24317  1.000 42.18705  ? 169 LYS L CB   1 
ATOM   5842 C CG   . LYS B 2 175 ? 21.33221  10.02248  21.92899  1.000 46.40127  ? 169 LYS L CG   1 
ATOM   5843 C CD   . LYS B 2 175 ? 22.71579  9.55553   21.48118  1.000 55.64332  ? 169 LYS L CD   1 
ATOM   5844 C CE   . LYS B 2 175 ? 23.83938  10.14699  22.32554  1.000 61.35230  ? 169 LYS L CE   1 
ATOM   5845 N NZ   . LYS B 2 175 ? 25.02297  9.23209   22.37136  1.000 57.16940  ? 169 LYS L NZ   1 
ATOM   5846 H H    . LYS B 2 175 ? 18.91199  10.06991  20.10445  1.000 36.40228  ? 169 LYS L H    1 
ATOM   5847 H HA   . LYS B 2 175 ? 19.15394  11.78245  22.20203  1.000 44.27674  ? 169 LYS L HA   1 
ATOM   5848 H HB2  . LYS B 2 175 ? 21.18379  11.27013  20.31635  1.000 50.63129  ? 169 LYS L HB2  1 
ATOM   5849 H HB3  . LYS B 2 175 ? 21.35107  12.05262  21.68936  1.000 50.63129  ? 169 LYS L HB3  1 
ATOM   5850 H HG2  . LYS B 2 175 ? 21.35888  10.16478  22.88812  1.000 55.68836  ? 169 LYS L HG2  1 
ATOM   5851 H HG3  . LYS B 2 175 ? 20.69510  9.32306   21.71496  1.000 55.68836  ? 169 LYS L HG3  1 
ATOM   5852 H HD2  . LYS B 2 175 ? 22.76285  8.58943   21.55423  1.000 66.77882  ? 169 LYS L HD2  1 
ATOM   5853 H HD3  . LYS B 2 175 ? 22.85859  9.82597   20.56065  1.000 66.77882  ? 169 LYS L HD3  1 
ATOM   5854 H HE2  . LYS B 2 175 ? 24.12047  10.99205  21.94114  1.000 73.62960  ? 169 LYS L HE2  1 
ATOM   5855 H HE3  . LYS B 2 175 ? 23.52304  10.28383  23.23224  1.000 73.62960  ? 169 LYS L HE3  1 
ATOM   5856 H HZ1  . LYS B 2 175 ? 25.66983  9.59557   22.86284  1.000 68.61011  ? 169 LYS L HZ1  1 
ATOM   5857 H HZ2  . LYS B 2 175 ? 24.79080  8.45178   22.73096  1.000 68.61011  ? 169 LYS L HZ2  1 
ATOM   5858 H HZ3  . LYS B 2 175 ? 25.33046  9.09069   21.54821  1.000 68.61011  ? 169 LYS L HZ3  1 
ATOM   5859 N N    . ASP B 2 176 ? 18.87429  12.55037  19.10977  1.000 35.87090  ? 170 ASP L N    1 
ATOM   5860 C CA   . ASP B 2 176 ? 18.66703  13.60157  18.12032  1.000 36.03559  ? 170 ASP L CA   1 
ATOM   5861 C C    . ASP B 2 176 ? 17.20050  13.88544  17.82981  1.000 28.41760  ? 170 ASP L C    1 
ATOM   5862 O O    . ASP B 2 176 ? 16.87452  14.98190  17.35928  1.000 21.70329  ? 170 ASP L O    1 
ATOM   5863 C CB   . ASP B 2 176 ? 19.32792  13.21719  16.78706  1.000 36.79795  ? 170 ASP L CB   1 
ATOM   5864 C CG   . ASP B 2 176 ? 20.62166  13.95462  16.53220  1.000 58.02038  ? 170 ASP L CG   1 
ATOM   5865 O OD1  . ASP B 2 176 ? 21.17118  14.55671  17.48064  1.000 69.35180  ? 170 ASP L OD1  1 
ATOM   5866 O OD2  . ASP B 2 176 ? 21.08608  13.92954  15.36963  1.000 58.82732  ? 170 ASP L OD2  1 
ATOM   5867 H H    . ASP B 2 176 ? 18.87097  11.76507  18.75921  1.000 43.05191  ? 170 ASP L H    1 
ATOM   5868 H HA   . ASP B 2 176 ? 19.07863  14.40806  18.46826  1.000 43.24954  ? 170 ASP L HA   1 
ATOM   5869 H HB2  . ASP B 2 176 ? 19.52254  12.26695  16.79467  1.000 44.16438  ? 170 ASP L HB2  1 
ATOM   5870 H HB3  . ASP B 2 176 ? 18.71805  13.42513  16.06199  1.000 44.16438  ? 170 ASP L HB3  1 
ATOM   5871 N N    . SER B 2 177 ? 16.31850  12.90979  18.04167  1.000 22.66507  ? 171 SER L N    1 
ATOM   5872 C CA   . SER B 2 177 ? 14.91033  12.99216  17.68008  1.000 22.43394  ? 171 SER L CA   1 
ATOM   5873 C C    . SER B 2 177 ? 14.69183  13.06444  16.16930  1.000 20.20325  ? 171 SER L C    1 
ATOM   5874 O O    . SER B 2 177 ? 13.57613  13.33250  15.72810  1.000 17.59568  ? 171 SER L O    1 
ATOM   5875 C CB   . SER B 2 177 ? 14.23694  14.19161  18.36217  1.000 18.99166  ? 171 SER L CB   1 
ATOM   5876 O OG   . SER B 2 177 ? 14.39889  14.11310  19.77053  1.000 19.73799  ? 171 SER L OG   1 
ATOM   5877 H H    . SER B 2 177 ? 16.52597  12.16059  18.40945  1.000 27.20491  ? 171 SER L H    1 
ATOM   5878 H HA   . SER B 2 177 ? 14.46875  12.18450  17.98600  1.000 26.92756  ? 171 SER L HA   1 
ATOM   5879 H HB2  . SER B 2 177 ? 14.64523  15.01058  18.04049  1.000 22.79682  ? 171 SER L HB2  1 
ATOM   5880 H HB3  . SER B 2 177 ? 13.29034  14.18741  18.15041  1.000 22.79682  ? 171 SER L HB3  1 
ATOM   5881 H HG   . SER B 2 177 ? 14.04673  13.40812  20.06136  1.000 23.69242  ? 171 SER L HG   1 
ATOM   5882 N N    . THR B 2 178 ? 15.72011  12.81854  15.36244  1.000 21.16368  ? 172 THR L N    1 
ATOM   5883 C CA   . THR B 2 178 ? 15.56984  12.84169  13.91685  1.000 19.67035  ? 172 THR L CA   1 
ATOM   5884 C C    . THR B 2 178 ? 15.17346  11.46651  13.38909  1.000 23.60632  ? 172 THR L C    1 
ATOM   5885 O O    . THR B 2 178 ? 15.26688  10.44834  14.07938  1.000 21.54982  ? 172 THR L O    1 
ATOM   5886 C CB   . THR B 2 178 ? 16.86291  13.29611  13.23662  1.000 20.48926  ? 172 THR L CB   1 
ATOM   5887 O OG1  . THR B 2 178 ? 17.93969  12.42937  13.61505  1.000 25.38469  ? 172 THR L OG1  1 
ATOM   5888 C CG2  . THR B 2 178 ? 17.19341  14.71393  13.63053  1.000 23.75397  ? 172 THR L CG2  1 
ATOM   5889 H H    . THR B 2 178 ? 16.51608  12.63552  15.63177  1.000 25.40325  ? 172 THR L H    1 
ATOM   5890 H HA   . THR B 2 178 ? 14.86855  13.47505  13.69789  1.000 23.61126  ? 172 THR L HA   1 
ATOM   5891 H HB   . THR B 2 178 ? 16.75174  13.26385  12.27356  1.000 24.59394  ? 172 THR L HB   1 
ATOM   5892 H HG1  . THR B 2 178 ? 17.77797  11.64406  13.36458  1.000 30.46847  ? 172 THR L HG1  1 
ATOM   5893 H HG21 . THR B 2 178 ? 18.00020  15.00469  13.17726  1.000 28.51159  ? 172 THR L HG21 1 
ATOM   5894 H HG22 . THR B 2 178 ? 16.46428  15.30488  13.38548  1.000 28.51159  ? 172 THR L HG22 1 
ATOM   5895 H HG23 . THR B 2 178 ? 17.33386  14.76786  14.58879  1.000 28.51159  ? 172 THR L HG23 1 
ATOM   5896 N N    . TYR B 2 179 ? 14.72410  11.45521  12.13838  1.000 17.37541  ? 173 TYR L N    1 
ATOM   5897 C CA   . TYR B 2 179 ? 14.35738  10.24504  11.42611  1.000 19.51044  ? 173 TYR L CA   1 
ATOM   5898 C C    . TYR B 2 179 ? 15.34232  10.00948  10.29204  1.000 21.07724  ? 173 TYR L C    1 
ATOM   5899 O O    . TYR B 2 179 ? 16.06062  10.91569  9.86438   1.000 17.94879  ? 173 TYR L O    1 
ATOM   5900 C CB   . TYR B 2 179 ? 12.94531  10.34043  10.83490  1.000 19.30170  ? 173 TYR L CB   1 
ATOM   5901 C CG   . TYR B 2 179 ? 11.83164  10.58009  11.83354  1.000 19.55617  ? 173 TYR L CG   1 
ATOM   5902 C CD1  . TYR B 2 179 ? 11.21433  9.52086   12.47946  1.000 21.21244  ? 173 TYR L CD1  1 
ATOM   5903 C CD2  . TYR B 2 179 ? 11.38564  11.86326  12.10841  1.000 24.18913  ? 173 TYR L CD2  1 
ATOM   5904 C CE1  . TYR B 2 179 ? 10.19410  9.73071   13.37886  1.000 25.66418  ? 173 TYR L CE1  1 
ATOM   5905 C CE2  . TYR B 2 179 ? 10.36551  12.08679  13.00733  1.000 23.07326  ? 173 TYR L CE2  1 
ATOM   5906 C CZ   . TYR B 2 179 ? 9.76975   11.01754  13.64103  1.000 29.04994  ? 173 TYR L CZ   1 
ATOM   5907 O OH   . TYR B 2 179 ? 8.75018   11.22946  14.54153  1.000 35.63139  ? 173 TYR L OH   1 
ATOM   5908 H H    . TYR B 2 179 ? 14.62033  12.16648  11.66623  1.000 20.85732  ? 173 TYR L H    1 
ATOM   5909 H HA   . TYR B 2 179 ? 14.37882  9.49797   12.04443  1.000 23.41937  ? 173 TYR L HA   1 
ATOM   5910 H HB2  . TYR B 2 179 ? 12.92877  11.07612  10.20293  1.000 23.16887  ? 173 TYR L HB2  1 
ATOM   5911 H HB3  . TYR B 2 179 ? 12.74904  9.50701   10.37905  1.000 23.16887  ? 173 TYR L HB3  1 
ATOM   5912 H HD1  . TYR B 2 179 ? 11.49470  8.65210   12.30187  1.000 25.46176  ? 173 TYR L HD1  1 
ATOM   5913 H HD2  . TYR B 2 179 ? 11.78201  12.58638  11.67842  1.000 29.03379  ? 173 TYR L HD2  1 
ATOM   5914 H HE1  . TYR B 2 179 ? 9.79287   9.00951   13.80755  1.000 30.80385  ? 173 TYR L HE1  1 
ATOM   5915 H HE2  . TYR B 2 179 ? 10.08065  12.95400  13.18540  1.000 27.69475  ? 173 TYR L HE2  1 
ATOM   5916 H HH   . TYR B 2 179 ? 8.59196   12.05173  14.60810  1.000 42.76450  ? 173 TYR L HH   1 
ATOM   5917 N N    . SER B 2 180 ? 15.36388  8.77505   9.80906   1.000 18.61508  ? 174 SER L N    1 
ATOM   5918 C CA   . SER B 2 180 ? 16.00935  8.43546   8.55116   1.000 17.90863  ? 174 SER L CA   1 
ATOM   5919 C C    . SER B 2 180 ? 15.01711  7.63323   7.72044   1.000 18.66875  ? 174 SER L C    1 
ATOM   5920 O O    . SER B 2 180 ? 14.16881  6.91967   8.25817   1.000 17.64795  ? 174 SER L O    1 
ATOM   5921 C CB   . SER B 2 180 ? 17.31043  7.65888   8.76950   1.000 24.03671  ? 174 SER L CB   1 
ATOM   5922 O OG   . SER B 2 180 ? 18.31246  8.51172   9.31491   1.000 25.85959  ? 174 SER L OG   1 
ATOM   5923 H H    . SER B 2 180 ? 15.00232  8.10093   10.20204  1.000 22.34493  ? 174 SER L H    1 
ATOM   5924 H HA   . SER B 2 180 ? 16.24973  9.23464   8.05676   1.000 21.49719  ? 174 SER L HA   1 
ATOM   5925 H HB2  . SER B 2 180 ? 17.14472  6.92885   9.38635   1.000 28.85089  ? 174 SER L HB2  1 
ATOM   5926 H HB3  . SER B 2 180 ? 17.61888  7.31052   7.91839   1.000 28.85089  ? 174 SER L HB3  1 
ATOM   5927 H HG   . SER B 2 180 ? 19.03051  8.08652   9.41087   1.000 31.03834  ? 174 SER L HG   1 
ATOM   5928 N N    . LEU B 2 181 ? 15.10861  7.78236   6.40340   1.000 15.44550  ? 175 LEU L N    1 
ATOM   5929 C CA   . LEU B 2 181 ? 14.13267  7.21010   5.49129   1.000 16.88236  ? 175 LEU L CA   1 
ATOM   5930 C C    . LEU B 2 181 ? 14.85928  6.62430   4.29437   1.000 20.12059  ? 175 LEU L C    1 
ATOM   5931 O O    . LEU B 2 181 ? 15.85142  7.18498   3.82378   1.000 17.29603  ? 175 LEU L O    1 
ATOM   5932 C CB   . LEU B 2 181 ? 13.11610  8.27040   5.03629   1.000 19.71465  ? 175 LEU L CB   1 
ATOM   5933 C CG   . LEU B 2 181 ? 11.98946  7.84818   4.08971   1.000 19.87865  ? 175 LEU L CG   1 
ATOM   5934 C CD1  . LEU B 2 181 ? 10.72526  8.65891   4.35924   1.000 25.36921  ? 175 LEU L CD1  1 
ATOM   5935 C CD2  . LEU B 2 181 ? 12.40608  7.99878   2.63983   1.000 22.50421  ? 175 LEU L CD2  1 
ATOM   5936 H H    . LEU B 2 181 ? 15.73753  8.21789   6.01049   1.000 18.54144  ? 175 LEU L H    1 
ATOM   5937 H HA   . LEU B 2 181 ? 13.64593  6.49306   5.92701   1.000 20.26567  ? 175 LEU L HA   1 
ATOM   5938 H HB2  . LEU B 2 181 ? 12.68937  8.62596   5.83151   1.000 23.66442  ? 175 LEU L HB2  1 
ATOM   5939 H HB3  . LEU B 2 181 ? 13.60911  8.97181   4.58256   1.000 23.66442  ? 175 LEU L HB3  1 
ATOM   5940 H HG   . LEU B 2 181 ? 11.79407  6.91158   4.24945   1.000 23.86121  ? 175 LEU L HG   1 
ATOM   5941 H HD11 . LEU B 2 181 ? 10.03423  8.38251   3.73716   1.000 30.44988  ? 175 LEU L HD11 1 
ATOM   5942 H HD12 . LEU B 2 181 ? 10.43433  8.49672   5.27026   1.000 30.44988  ? 175 LEU L HD12 1 
ATOM   5943 H HD13 . LEU B 2 181 ? 10.92227  9.60088   4.23765   1.000 30.44988  ? 175 LEU L HD13 1 
ATOM   5944 H HD21 . LEU B 2 181 ? 11.63920  7.82657   2.07137   1.000 27.01188  ? 175 LEU L HD21 1 
ATOM   5945 H HD22 . LEU B 2 181 ? 12.72816  8.90237   2.49603   1.000 27.01188  ? 175 LEU L HD22 1 
ATOM   5946 H HD23 . LEU B 2 181 ? 13.11122  7.36150   2.44604   1.000 27.01188  ? 175 LEU L HD23 1 
ATOM   5947 N N    . SER B 2 182 ? 14.37797  5.48064   3.82641   1.000 16.69268  ? 176 SER L N    1 
ATOM   5948 C CA   . SER B 2 182 ? 14.84747  4.87753   2.59282   1.000 14.72120  ? 176 SER L CA   1 
ATOM   5949 C C    . SER B 2 182 ? 13.67845  4.79688   1.62549   1.000 18.90499  ? 176 SER L C    1 
ATOM   5950 O O    . SER B 2 182 ? 12.55042  4.47777   2.01751   1.000 20.53196  ? 176 SER L O    1 
ATOM   5951 C CB   . SER B 2 182 ? 15.43471  3.48537   2.82294   1.000 20.35951  ? 176 SER L CB   1 
ATOM   5952 O OG   . SER B 2 182 ? 14.45554  2.60182   3.34051   1.000 28.52453  ? 176 SER L OG   1 
ATOM   5953 H H    . SER B 2 182 ? 13.76257  5.02523   4.21818   1.000 20.03805  ? 176 SER L H    1 
ATOM   5954 H HA   . SER B 2 182 ? 15.54992  5.42271   2.20522   1.000 17.67228  ? 176 SER L HA   1 
ATOM   5955 H HB2  . SER B 2 182 ? 15.75927  3.13644   1.97807   1.000 24.43825  ? 176 SER L HB2  1 
ATOM   5956 H HB3  . SER B 2 182 ? 16.16572  3.55234   3.45700   1.000 24.43825  ? 176 SER L HB3  1 
ATOM   5957 H HG   . SER B 2 182 ? 14.78532  1.83620   3.44383   1.000 34.23627  ? 176 SER L HG   1 
ATOM   5958 N N    . SER B 2 183 ? 13.94322  5.13504   0.37437   1.000 15.31631  ? 177 SER L N    1 
ATOM   5959 C CA   . SER B 2 183 ? 13.01518  4.89365   -0.71616  1.000 18.46111  ? 177 SER L CA   1 
ATOM   5960 C C    . SER B 2 183 ? 13.69466  3.99002   -1.73064  1.000 20.58704  ? 177 SER L C    1 
ATOM   5961 O O    . SER B 2 183 ? 14.81284  4.26946   -2.16564  1.000 18.40931  ? 177 SER L O    1 
ATOM   5962 C CB   . SER B 2 183 ? 12.57319  6.19269   -1.37621  1.000 22.57989  ? 177 SER L CB   1 
ATOM   5963 O OG   . SER B 2 183 ? 11.65400  5.91223   -2.40988  1.000 17.37370  ? 177 SER L OG   1 
ATOM   5964 H H    . SER B 2 183 ? 14.67340  5.51565   0.12622   1.000 18.38641  ? 177 SER L H    1 
ATOM   5965 H HA   . SER B 2 183 ? 12.22024  4.45175   -0.37898  1.000 22.16016  ? 177 SER L HA   1 
ATOM   5966 H HB2  . SER B 2 183 ? 12.14760  6.75974   -0.71421  1.000 27.10270  ? 177 SER L HB2  1 
ATOM   5967 H HB3  . SER B 2 183 ? 13.34760  6.64206   -1.74938  1.000 27.10270  ? 177 SER L HB3  1 
ATOM   5968 H HG   . SER B 2 183 ? 11.37595  6.62854   -2.74926  1.000 20.85528  ? 177 SER L HG   1 
ATOM   5969 N N    . THR B 2 184 ? 13.02322  2.91074   -2.10228  1.000 18.81370  ? 178 THR L N    1 
ATOM   5970 C CA   . THR B 2 184 ? 13.59046  1.90739   -2.98981  1.000 17.39761  ? 178 THR L CA   1 
ATOM   5971 C C    . THR B 2 184 ? 12.71713  1.81815   -4.23249  1.000 20.69167  ? 178 THR L C    1 
ATOM   5972 O O    . THR B 2 184 ? 11.51352  1.55574   -4.13086  1.000 18.28032  ? 178 THR L O    1 
ATOM   5973 C CB   . THR B 2 184 ? 13.69353  0.56078   -2.27412  1.000 18.42341  ? 178 THR L CB   1 
ATOM   5974 O OG1  . THR B 2 184 ? 14.38627  0.74039   -1.02765  1.000 22.79225  ? 178 THR L OG1  1 
ATOM   5975 C CG2  . THR B 2 184 ? 14.45304  -0.42996  -3.11551  1.000 20.02783  ? 178 THR L CG2  1 
ATOM   5976 H H    . THR B 2 184 ? 12.22086  2.73396   -1.84816  1.000 22.58327  ? 178 THR L H    1 
ATOM   5977 H HA   . THR B 2 184 ? 14.48162  2.16591   -3.27247  1.000 20.88397  ? 178 THR L HA   1 
ATOM   5978 H HB   . THR B 2 184 ? 12.80368  0.20990   -2.11305  1.000 22.11492  ? 178 THR L HB   1 
ATOM   5979 H HG1  . THR B 2 184 ? 14.45086  0.00529   -0.62634  1.000 27.35753  ? 178 THR L HG1  1 
ATOM   5980 H HG21 . THR B 2 184 ? 14.57037  -1.25942  -2.62650  1.000 24.04023  ? 178 THR L HG21 1 
ATOM   5981 H HG22 . THR B 2 184 ? 13.96527  -0.61318  -3.93368  1.000 24.04023  ? 178 THR L HG22 1 
ATOM   5982 H HG23 . THR B 2 184 ? 15.32562  -0.07229  -3.34260  1.000 24.04023  ? 178 THR L HG23 1 
ATOM   5983 N N    . LEU B 2 185 ? 13.31997  2.09128   -5.38871  1.000 19.93800  ? 179 LEU L N    1 
ATOM   5984 C CA   . LEU B 2 185 ? 12.68529  1.94858   -6.69149  1.000 18.98665  ? 179 LEU L CA   1 
ATOM   5985 C C    . LEU B 2 185 ? 13.08016  0.59632   -7.26531  1.000 20.45158  ? 179 LEU L C    1 
ATOM   5986 O O    . LEU B 2 185 ? 14.27088  0.28293   -7.35956  1.000 18.30508  ? 179 LEU L O    1 
ATOM   5987 C CB   . LEU B 2 185 ? 13.12358  3.07720   -7.62408  1.000 20.85684  ? 179 LEU L CB   1 
ATOM   5988 C CG   . LEU B 2 185 ? 12.59255  3.08841   -9.05831  1.000 22.73932  ? 179 LEU L CG   1 
ATOM   5989 C CD1  . LEU B 2 185 ? 11.15286  3.56551   -9.10816  1.000 23.03404  ? 179 LEU L CD1  1 
ATOM   5990 C CD2  . LEU B 2 185 ? 13.47950  3.96671   -9.93212  1.000 23.71324  ? 179 LEU L CD2  1 
ATOM   5991 H H    . LEU B 2 185 ? 14.13088  2.37242   -5.44340  1.000 23.93243  ? 179 LEU L H    1 
ATOM   5992 H HA   . LEU B 2 185 ? 11.71942  1.98687   -6.61060  1.000 22.79082  ? 179 LEU L HA   1 
ATOM   5993 H HB2  . LEU B 2 185 ? 12.84599  3.91437   -7.22036  1.000 25.03504  ? 179 LEU L HB2  1 
ATOM   5994 H HB3  . LEU B 2 185 ? 14.09091  3.04441   -7.68809  1.000 25.03504  ? 179 LEU L HB3  1 
ATOM   5995 H HG   . LEU B 2 185 ? 12.60880  2.18360   -9.40754  1.000 27.29402  ? 179 LEU L HG   1 
ATOM   5996 H HD11 . LEU B 2 185 ? 10.85737  3.58181   -10.03192 1.000 27.64768  ? 179 LEU L HD11 1 
ATOM   5997 H HD12 . LEU B 2 185 ? 10.60013  2.95573   -8.59478  1.000 27.64768  ? 179 LEU L HD12 1 
ATOM   5998 H HD13 . LEU B 2 185 ? 11.10224  4.45686   -8.72891  1.000 27.64768  ? 179 LEU L HD13 1 
ATOM   5999 H HD21 . LEU B 2 185 ? 13.11968  3.98187   -10.83279 1.000 28.46272  ? 179 LEU L HD21 1 
ATOM   6000 H HD22 . LEU B 2 185 ? 13.49307  4.86493   -9.56618  1.000 28.46272  ? 179 LEU L HD22 1 
ATOM   6001 H HD23 . LEU B 2 185 ? 14.37724  3.59943   -9.94071  1.000 28.46272  ? 179 LEU L HD23 1 
ATOM   6002 N N    . THR B 2 186 ? 12.08768  -0.20393  -7.63235  1.000 21.93436  ? 180 THR L N    1 
ATOM   6003 C CA   . THR B 2 186 ? 12.31256  -1.55139  -8.13258  1.000 22.54345  ? 180 THR L CA   1 
ATOM   6004 C C    . THR B 2 186 ? 11.95186  -1.60590  -9.60960  1.000 24.44168  ? 180 THR L C    1 
ATOM   6005 O O    . THR B 2 186 ? 10.85012  -1.20729  -10.00104 1.000 24.03844  ? 180 THR L O    1 
ATOM   6006 C CB   . THR B 2 186 ? 11.49069  -2.57499  -7.34720  1.000 29.28014  ? 180 THR L CB   1 
ATOM   6007 O OG1  . THR B 2 186 ? 11.87669  -2.53900  -5.96610  1.000 26.13648  ? 180 THR L OG1  1 
ATOM   6008 C CG2  . THR B 2 186 ? 11.71009  -3.98130  -7.90803  1.000 33.10468  ? 180 THR L CG2  1 
ATOM   6009 H H    . THR B 2 186 ? 11.25727  0.01727   -7.59953  1.000 26.32807  ? 180 THR L H    1 
ATOM   6010 H HA   . THR B 2 186 ? 13.25036  -1.78013  -8.03708  1.000 27.05898  ? 180 THR L HA   1 
ATOM   6011 H HB   . THR B 2 186 ? 10.54685  -2.36408  -7.42183  1.000 35.14300  ? 180 THR L HB   1 
ATOM   6012 H HG1  . THR B 2 186 ? 12.69133  -2.72935  -5.89042  1.000 31.37061  ? 180 THR L HG1  1 
ATOM   6013 H HG21 . THR B 2 186 ? 11.36732  -4.64321  -7.28731  1.000 39.73245  ? 180 THR L HG21 1 
ATOM   6014 H HG22 . THR B 2 186 ? 11.24856  -4.07607  -8.75591  1.000 39.73245  ? 180 THR L HG22 1 
ATOM   6015 H HG23 . THR B 2 186 ? 12.65714  -4.13954  -8.04572  1.000 39.73245  ? 180 THR L HG23 1 
ATOM   6016 N N    . LEU B 2 187 ? 12.89102  -2.08030  -10.41928 1.000 25.26835  ? 181 LEU L N    1 
ATOM   6017 C CA   . LEU B 2 187 ? 12.68924  -2.27315  -11.84380 1.000 20.82118  ? 181 LEU L CA   1 
ATOM   6018 C C    . LEU B 2 187 ? 13.23767  -3.63650  -12.22340 1.000 23.44106  ? 181 LEU L C    1 
ATOM   6019 O O    . LEU B 2 187 ? 14.03359  -4.23033  -11.49533 1.000 22.97889  ? 181 LEU L O    1 
ATOM   6020 C CB   . LEU B 2 187 ? 13.39676  -1.19335  -12.66533 1.000 24.67688  ? 181 LEU L CB   1 
ATOM   6021 C CG   . LEU B 2 187 ? 12.93104  0.24460   -12.45690 1.000 34.57175  ? 181 LEU L CG   1 
ATOM   6022 C CD1  . LEU B 2 187 ? 14.06651  1.20076   -12.79064 1.000 36.73062  ? 181 LEU L CD1  1 
ATOM   6023 C CD2  . LEU B 2 187 ? 11.70785  0.54401   -13.30790 1.000 39.85321  ? 181 LEU L CD2  1 
ATOM   6024 H H    . LEU B 2 187 ? 13.67835  -2.30419  -10.15551 1.000 30.32885  ? 181 LEU L H    1 
ATOM   6025 H HA   . LEU B 2 187 ? 11.74220  -2.23720  -12.05047 1.000 24.99225  ? 181 LEU L HA   1 
ATOM   6026 H HB2  . LEU B 2 187 ? 14.34109  -1.22056  -12.44532 1.000 29.61909  ? 181 LEU L HB2  1 
ATOM   6027 H HB3  . LEU B 2 187 ? 13.26882  -1.39983  -13.60442 1.000 29.61909  ? 181 LEU L HB3  1 
ATOM   6028 H HG   . LEU B 2 187 ? 12.67836  0.37264   -11.52919 1.000 41.49293  ? 181 LEU L HG   1 
ATOM   6029 H HD11 . LEU B 2 187 ? 13.74727  2.11262   -12.70401 1.000 44.08358  ? 181 LEU L HD11 1 
ATOM   6030 H HD12 . LEU B 2 187 ? 14.80001  1.04718   -12.17477 1.000 44.08358  ? 181 LEU L HD12 1 
ATOM   6031 H HD13 . LEU B 2 187 ? 14.35928  1.03787   -13.70094 1.000 44.08358  ? 181 LEU L HD13 1 
ATOM   6032 H HD21 . LEU B 2 187 ? 11.42427  1.45688   -13.14314 1.000 47.83068  ? 181 LEU L HD21 1 
ATOM   6033 H HD22 . LEU B 2 187 ? 11.93917  0.43323   -14.24338 1.000 47.83068  ? 181 LEU L HD22 1 
ATOM   6034 H HD23 . LEU B 2 187 ? 10.99765  -0.07145  -13.06764 1.000 47.83068  ? 181 LEU L HD23 1 
ATOM   6035 N N    . SER B 2 188 ? 12.80396  -4.14084  -13.36921 1.000 22.59438  ? 182 SER L N    1 
ATOM   6036 C CA   . SER B 2 188 ? 13.49046  -5.28857  -13.93248 1.000 21.68297  ? 182 SER L CA   1 
ATOM   6037 C C    . SER B 2 188 ? 14.85436  -4.85217  -14.46134 1.000 20.71631  ? 182 SER L C    1 
ATOM   6038 O O    . SER B 2 188 ? 15.07326  -3.68424  -14.79433 1.000 19.18806  ? 182 SER L O    1 
ATOM   6039 C CB   . SER B 2 188 ? 12.66672  -5.91476  -15.05809 1.000 28.95029  ? 182 SER L CB   1 
ATOM   6040 O OG   . SER B 2 188 ? 12.68148  -5.07781  -16.20111 1.000 30.88310  ? 182 SER L OG   1 
ATOM   6041 H H    . SER B 2 188 ? 12.13648  -3.84585  -13.82424 1.000 27.12009  ? 182 SER L H    1 
ATOM   6042 H HA   . SER B 2 188 ? 13.61621  -5.96787  -13.25157 1.000 26.02639  ? 182 SER L HA   1 
ATOM   6043 H HB2  . SER B 2 188 ? 13.04774  -6.77620  -15.28971 1.000 34.74719  ? 182 SER L HB2  1 
ATOM   6044 H HB3  . SER B 2 188 ? 11.75122  -6.02687  -14.75777 1.000 34.74719  ? 182 SER L HB3  1 
ATOM   6045 H HG   . SER B 2 188 ? 12.24488  -5.43432  -16.82390 1.000 37.06655  ? 182 SER L HG   1 
ATOM   6046 N N    . LYS B 2 189 ? 15.78074  -5.80983  -14.53848 1.000 23.61536  ? 183 LYS L N    1 
ATOM   6047 C CA   . LYS B 2 189 ? 17.07996  -5.52636  -15.14019 1.000 25.12032  ? 183 LYS L CA   1 
ATOM   6048 C C    . LYS B 2 189 ? 16.92844  -4.90785  -16.52902 1.000 24.82689  ? 183 LYS L C    1 
ATOM   6049 O O    . LYS B 2 189 ? 17.63714  -3.95457  -16.87738 1.000 22.68848  ? 183 LYS L O    1 
ATOM   6050 C CB   . LYS B 2 189 ? 17.90577  -6.81050  -15.21514 1.000 25.33006  ? 183 LYS L CB   1 
ATOM   6051 C CG   . LYS B 2 189 ? 19.28154  -6.64076  -15.85372 1.000 30.63676  ? 183 LYS L CG   1 
ATOM   6052 C CD   . LYS B 2 189 ? 19.84175  -7.97992  -16.30064 1.000 33.78899  ? 183 LYS L CD   1 
ATOM   6053 C CE   . LYS B 2 189 ? 20.56939  -7.87922  -17.63368 1.000 44.33641  ? 183 LYS L CE   1 
ATOM   6054 N NZ   . LYS B 2 189 ? 22.02092  -7.59668  -17.47335 1.000 56.08259  ? 183 LYS L NZ   1 
ATOM   6055 H H    . LYS B 2 189 ? 15.68268  -6.61583  -14.25501 1.000 28.34526  ? 183 LYS L H    1 
ATOM   6056 H HA   . LYS B 2 189 ? 17.55369  -4.89119  -14.58069 1.000 30.15122  ? 183 LYS L HA   1 
ATOM   6057 H HB2  . LYS B 2 189 ? 18.03987  -7.14472  -14.31447 1.000 30.40290  ? 183 LYS L HB2  1 
ATOM   6058 H HB3  . LYS B 2 189 ? 17.41669  -7.46219  -15.74145 1.000 30.40290  ? 183 LYS L HB3  1 
ATOM   6059 H HG2  . LYS B 2 189 ? 19.20879  -6.06373  -16.63002 1.000 36.77095  ? 183 LYS L HG2  1 
ATOM   6060 H HG3  . LYS B 2 189 ? 19.89222  -6.25247  -15.20780 1.000 36.77095  ? 183 LYS L HG3  1 
ATOM   6061 H HD2  . LYS B 2 189 ? 20.47128  -8.30038  -15.63588 1.000 40.55362  ? 183 LYS L HD2  1 
ATOM   6062 H HD3  . LYS B 2 189 ? 19.11373  -8.61310  -16.40053 1.000 40.55362  ? 183 LYS L HD3  1 
ATOM   6063 H HE2  . LYS B 2 189 ? 20.47781  -8.71985  -18.10891 1.000 53.21052  ? 183 LYS L HE2  1 
ATOM   6064 H HE3  . LYS B 2 189 ? 20.17911  -7.15967  -18.15409 1.000 53.21052  ? 183 LYS L HE3  1 
ATOM   6065 H HZ1  . LYS B 2 189 ? 22.40718  -7.52538  -18.27199 1.000 67.30594  ? 183 LYS L HZ1  1 
ATOM   6066 H HZ2  . LYS B 2 189 ? 22.13533  -6.83460  -17.02810 1.000 67.30594  ? 183 LYS L HZ2  1 
ATOM   6067 H HZ3  . LYS B 2 189 ? 22.41140  -8.25660  -17.02154 1.000 67.30594  ? 183 LYS L HZ3  1 
ATOM   6068 N N    . ALA B 2 190 ? 16.00922  -5.43991  -17.33902 1.000 28.43261  ? 184 ALA L N    1 
ATOM   6069 C CA   . ALA B 2 190 ? 15.85487  -4.94632  -18.70527 1.000 26.20152  ? 184 ALA L CA   1 
ATOM   6070 C C    . ALA B 2 190 ? 15.36311  -3.50536  -18.71078 1.000 23.51014  ? 184 ALA L C    1 
ATOM   6071 O O    . ALA B 2 190 ? 15.93286  -2.63579  -19.39397 1.000 29.64761  ? 184 ALA L O    1 
ATOM   6072 C CB   . ALA B 2 190 ? 14.89276  -5.84890  -19.48006 1.000 29.58742  ? 184 ALA L CB   1 
ATOM   6073 H H    . ALA B 2 190 ? 15.47235  -6.07653  -17.12434 1.000 34.12597  ? 184 ALA L H    1 
ATOM   6074 H HA   . ALA B 2 190 ? 16.71652  -4.97295  -19.14996 1.000 31.44865  ? 184 ALA L HA   1 
ATOM   6075 H HB1  . ALA B 2 190 ? 14.80321  -5.51177  -20.38517 1.000 35.51174  ? 184 ALA L HB1  1 
ATOM   6076 H HB2  . ALA B 2 190 ? 15.24994  -6.75059  -19.49676 1.000 35.51174  ? 184 ALA L HB2  1 
ATOM   6077 H HB3  . ALA B 2 190 ? 14.02935  -5.84327  -19.03804 1.000 35.51174  ? 184 ALA L HB3  1 
ATOM   6078 N N    . ASP B 2 191 ? 14.30340  -3.23106  -17.94923 1.000 24.76006  ? 185 ASP L N    1 
ATOM   6079 C CA   . ASP B 2 191 ? 13.82847  -1.85957  -17.83007 1.000 22.47793  ? 185 ASP L CA   1 
ATOM   6080 C C    . ASP B 2 191 ? 14.93860  -0.94201  -17.33482 1.000 23.90605  ? 185 ASP L C    1 
ATOM   6081 O O    . ASP B 2 191 ? 15.13026  0.15587   -17.87180 1.000 21.18961  ? 185 ASP L O    1 
ATOM   6082 C CB   . ASP B 2 191 ? 12.61708  -1.80361  -16.90127 1.000 30.13118  ? 185 ASP L CB   1 
ATOM   6083 C CG   . ASP B 2 191 ? 11.36511  -2.38902  -17.53759 1.000 42.92729  ? 185 ASP L CG   1 
ATOM   6084 O OD1  . ASP B 2 191 ? 11.38649  -2.67805  -18.75443 1.000 49.80179  ? 185 ASP L OD1  1 
ATOM   6085 O OD2  . ASP B 2 191 ? 10.35850  -2.56166  -16.82045 1.000 46.31262  ? 185 ASP L OD2  1 
ATOM   6086 H H    . ASP B 2 191 ? 13.85253  -3.81049  -17.50137 1.000 29.71891  ? 185 ASP L H    1 
ATOM   6087 H HA   . ASP B 2 191 ? 13.54495  -1.54319  -18.70209 1.000 26.98035  ? 185 ASP L HA   1 
ATOM   6088 H HB2  . ASP B 2 191 ? 12.81076  -2.31044  -16.09721 1.000 36.16425  ? 185 ASP L HB2  1 
ATOM   6089 H HB3  . ASP B 2 191 ? 12.43445  -0.87839  -16.67430 1.000 36.16425  ? 185 ASP L HB3  1 
ATOM   6090 N N    . TYR B 2 192 ? 15.70272  -1.38990  -16.33204 1.000 20.72478  ? 186 TYR L N    1 
ATOM   6091 C CA   . TYR B 2 192 ? 16.77491  -0.56314  -15.78587 1.000 19.70356  ? 186 TYR L CA   1 
ATOM   6092 C C    . TYR B 2 192 ? 17.78375  -0.19637  -16.86313 1.000 21.38836  ? 186 TYR L C    1 
ATOM   6093 O O    . TYR B 2 192 ? 18.19697  0.96262   -16.97556 1.000 20.61621  ? 186 TYR L O    1 
ATOM   6094 C CB   . TYR B 2 192 ? 17.46997  -1.29009  -14.62996 1.000 22.00090  ? 186 TYR L CB   1 
ATOM   6095 C CG   . TYR B 2 192 ? 18.67718  -0.55240  -14.09405 1.000 18.60320  ? 186 TYR L CG   1 
ATOM   6096 C CD1  . TYR B 2 192 ? 18.52926  0.61781   -13.35538 1.000 18.59455  ? 186 TYR L CD1  1 
ATOM   6097 C CD2  . TYR B 2 192 ? 19.95908  -1.02204  -14.32161 1.000 20.45118  ? 186 TYR L CD2  1 
ATOM   6098 C CE1  . TYR B 2 192 ? 19.63224  1.30123   -12.86462 1.000 18.31378  ? 186 TYR L CE1  1 
ATOM   6099 C CE2  . TYR B 2 192 ? 21.07182  -0.34490  -13.83277 1.000 22.13356  ? 186 TYR L CE2  1 
ATOM   6100 C CZ   . TYR B 2 192 ? 20.89946  0.81612   -13.10821 1.000 19.20256  ? 186 TYR L CZ   1 
ATOM   6101 O OH   . TYR B 2 192 ? 21.99109  1.49113   -12.61817 1.000 22.31529  ? 186 TYR L OH   1 
ATOM   6102 H H    . TYR B 2 192 ? 15.61968  -2.15936  -15.95703 1.000 24.87657  ? 186 TYR L H    1 
ATOM   6103 H HA   . TYR B 2 192 ? 16.38689  0.25486   -15.43769 1.000 23.65110  ? 186 TYR L HA   1 
ATOM   6104 H HB2  . TYR B 2 192 ? 16.83827  -1.39550  -13.90144 1.000 26.40791  ? 186 TYR L HB2  1 
ATOM   6105 H HB3  . TYR B 2 192 ? 17.76657  -2.15990  -14.94037 1.000 26.40791  ? 186 TYR L HB3  1 
ATOM   6106 H HD1  . TYR B 2 192 ? 17.67594  0.94744   -13.18782 1.000 22.32029  ? 186 TYR L HD1  1 
ATOM   6107 H HD2  . TYR B 2 192 ? 20.07879  -1.80433  -14.81007 1.000 24.54825  ? 186 TYR L HD2  1 
ATOM   6108 H HE1  . TYR B 2 192 ? 19.51737  2.08274   -12.37376 1.000 21.98337  ? 186 TYR L HE1  1 
ATOM   6109 H HE2  . TYR B 2 192 ? 21.92696  -0.67318  -13.99360 1.000 26.56711  ? 186 TYR L HE2  1 
ATOM   6110 H HH   . TYR B 2 192 ? 22.69718  1.09029   -12.83351 1.000 26.78518  ? 186 TYR L HH   1 
ATOM   6111 N N    . GLU B 2 193 ? 18.19415  -1.17588  -17.67025 1.000 22.22645  ? 187 GLU L N    1 
ATOM   6112 C CA   . GLU B 2 193 ? 19.19278  -0.91930  -18.69936 1.000 25.91256  ? 187 GLU L CA   1 
ATOM   6113 C C    . GLU B 2 193 ? 18.62865  -0.18470  -19.90628 1.000 23.85269  ? 187 GLU L C    1 
ATOM   6114 O O    . GLU B 2 193 ? 19.40303  0.20056   -20.78581 1.000 27.96604  ? 187 GLU L O    1 
ATOM   6115 C CB   . GLU B 2 193 ? 19.83050  -2.23258  -19.15610 1.000 28.72592  ? 187 GLU L CB   1 
ATOM   6116 C CG   . GLU B 2 193 ? 20.59404  -2.94234  -18.05514 1.000 32.46245  ? 187 GLU L CG   1 
ATOM   6117 C CD   . GLU B 2 193 ? 21.13729  -4.28638  -18.49170 1.000 53.56084  ? 187 GLU L CD   1 
ATOM   6118 O OE1  . GLU B 2 193 ? 20.51394  -4.92672  -19.36924 1.000 52.30872  ? 187 GLU L OE1  1 
ATOM   6119 O OE2  . GLU B 2 193 ? 22.18842  -4.69894  -17.95529 1.000 55.30183  ? 187 GLU L OE2  1 
ATOM   6120 H H    . GLU B 2 193 ? 17.91076  -1.98728  -17.63976 1.000 26.67857  ? 187 GLU L H    1 
ATOM   6121 H HA   . GLU B 2 193 ? 19.89142  -0.36655  -18.31560 1.000 31.10191  ? 187 GLU L HA   1 
ATOM   6122 H HB2  . GLU B 2 193 ? 19.13168  -2.82925  -19.46681 1.000 34.47794  ? 187 GLU L HB2  1 
ATOM   6123 H HB3  . GLU B 2 193 ? 20.45183  -2.04550  -19.87710 1.000 34.47794  ? 187 GLU L HB3  1 
ATOM   6124 H HG2  . GLU B 2 193 ? 21.34356  -2.38980  -17.78344 1.000 38.96178  ? 187 GLU L HG2  1 
ATOM   6125 H HG3  . GLU B 2 193 ? 20.00002  -3.08908  -17.30247 1.000 38.96178  ? 187 GLU L HG3  1 
ATOM   6126 N N    . LYS B 2 194 ? 17.31193  -0.00346  -19.98351 1.000 25.11677  ? 188 LYS L N    1 
ATOM   6127 C CA   . LYS B 2 194 ? 16.73774  0.82280   -21.04140 1.000 29.70117  ? 188 LYS L CA   1 
ATOM   6128 C C    . LYS B 2 194 ? 16.87018  2.32672   -20.78916 1.000 33.25348  ? 188 LYS L C    1 
ATOM   6129 O O    . LYS B 2 194 ? 16.52074  3.10997   -21.68040 1.000 26.64456  ? 188 LYS L O    1 
ATOM   6130 C CB   . LYS B 2 194 ? 15.25740  0.47437   -21.23429 1.000 26.98219  ? 188 LYS L CB   1 
ATOM   6131 C CG   . LYS B 2 194 ? 15.01560  -0.84605  -21.94637 1.000 31.48118  ? 188 LYS L CG   1 
ATOM   6132 C CD   . LYS B 2 194 ? 13.54030  -1.22851  -21.93686 1.000 34.61842  ? 188 LYS L CD   1 
ATOM   6133 C CE   . LYS B 2 194 ? 13.28881  -2.49814  -22.74612 1.000 40.48573  ? 188 LYS L CE   1 
ATOM   6134 N NZ   . LYS B 2 194 ? 14.05298  -3.67637  -22.24812 1.000 43.44345  ? 188 LYS L NZ   1 
ATOM   6135 H H    . LYS B 2 194 ? 16.73731  -0.34412  -19.44188 1.000 30.14695  ? 188 LYS L H    1 
ATOM   6136 H HA   . LYS B 2 194 ? 17.21044  0.62353   -21.86465 1.000 35.64824  ? 188 LYS L HA   1 
ATOM   6137 H HB2  . LYS B 2 194 ? 14.83554  0.42005   -20.36252 1.000 32.38546  ? 188 LYS L HB2  1 
ATOM   6138 H HB3  . LYS B 2 194 ? 14.84047  1.17365   -21.76162 1.000 32.38546  ? 188 LYS L HB3  1 
ATOM   6139 H HG2  . LYS B 2 194 ? 15.30421  -0.77020  -22.86933 1.000 37.78424  ? 188 LYS L HG2  1 
ATOM   6140 H HG3  . LYS B 2 194 ? 15.51456  -1.54754  -21.49933 1.000 37.78424  ? 188 LYS L HG3  1 
ATOM   6141 H HD2  . LYS B 2 194 ? 13.25501  -1.38719  -21.02344 1.000 41.54893  ? 188 LYS L HD2  1 
ATOM   6142 H HD3  . LYS B 2 194 ? 13.01907  -0.50952  -22.32707 1.000 41.54893  ? 188 LYS L HD3  1 
ATOM   6143 H HE2  . LYS B 2 194 ? 12.34465  -2.71629  -22.70294 1.000 48.58971  ? 188 LYS L HE2  1 
ATOM   6144 H HE3  . LYS B 2 194 ? 13.55125  -2.34104  -23.66663 1.000 48.58971  ? 188 LYS L HE3  1 
ATOM   6145 H HZ1  . LYS B 2 194 ? 13.87355  -4.38956  -22.74938 1.000 52.13897  ? 188 LYS L HZ1  1 
ATOM   6146 H HZ2  . LYS B 2 194 ? 14.92656  -3.51012  -22.28451 1.000 52.13897  ? 188 LYS L HZ2  1 
ATOM   6147 H HZ3  . LYS B 2 194 ? 13.82716  -3.85152  -21.40525 1.000 52.13897  ? 188 LYS L HZ3  1 
ATOM   6148 N N    . HIS B 2 195 ? 17.37258  2.75521   -19.62390 1.000 27.78633  ? 189 HIS L N    1 
ATOM   6149 C CA   . HIS B 2 195 ? 17.45586  4.17078   -19.28309 1.000 25.28237  ? 189 HIS L CA   1 
ATOM   6150 C C    . HIS B 2 195 ? 18.82648  4.51202   -18.71292 1.000 29.06241  ? 189 HIS L C    1 
ATOM   6151 O O    . HIS B 2 195 ? 19.58990  3.63763   -18.29226 1.000 21.84903  ? 189 HIS L O    1 
ATOM   6152 C CB   . HIS B 2 195 ? 16.37103  4.56637   -18.27606 1.000 22.28247  ? 189 HIS L CB   1 
ATOM   6153 C CG   . HIS B 2 195 ? 14.99287  4.19296   -18.71024 1.000 27.00691  ? 189 HIS L CG   1 
ATOM   6154 N ND1  . HIS B 2 195 ? 14.26991  4.94219   -19.61263 1.000 27.78397  ? 189 HIS L ND1  1 
ATOM   6155 C CD2  . HIS B 2 195 ? 14.21249  3.13643   -18.38500 1.000 28.25828  ? 189 HIS L CD2  1 
ATOM   6156 C CE1  . HIS B 2 195 ? 13.09592  4.37034   -19.81268 1.000 28.02049  ? 189 HIS L CE1  1 
ATOM   6157 N NE2  . HIS B 2 195 ? 13.03794  3.27124   -19.08362 1.000 29.81794  ? 189 HIS L NE2  1 
ATOM   6158 H H    . HIS B 2 195 ? 17.67406  2.23367   -19.01013 1.000 33.35043  ? 189 HIS L H    1 
ATOM   6159 H HA   . HIS B 2 195 ? 17.34051  4.68863   -20.09514 1.000 30.34568  ? 189 HIS L HA   1 
ATOM   6160 H HB2  . HIS B 2 195 ? 16.54845  4.12004   -17.43332 1.000 26.74580  ? 189 HIS L HB2  1 
ATOM   6161 H HB3  . HIS B 2 195 ? 16.39369  5.52830   -18.15323 1.000 26.74580  ? 189 HIS L HB3  1 
ATOM   6162 H HD1  . HIS B 2 195 ? 14.54030  5.66782   -19.98673 1.000 33.34759  ? 189 HIS L HD1  1 
ATOM   6163 H HD2  . HIS B 2 195 ? 14.43059  2.44835   -17.79858 1.000 33.91677  ? 189 HIS L HD2  1 
ATOM   6164 H HE1  . HIS B 2 195 ? 12.42436  4.68808   -20.37209 1.000 33.63142  ? 189 HIS L HE1  1 
ATOM   6165 N N    . LYS B 2 196 ? 19.12043  5.81392   -18.69254 1.000 23.33951  ? 190 LYS L N    1 
ATOM   6166 C CA   . LYS B 2 196 ? 20.44619  6.32785   -18.37182 1.000 22.16889  ? 190 LYS L CA   1 
ATOM   6167 C C    . LYS B 2 196 ? 20.50345  7.05291   -17.03629 1.000 22.40686  ? 190 LYS L C    1 
ATOM   6168 O O    . LYS B 2 196 ? 21.35043  6.73280   -16.19627 1.000 21.68574  ? 190 LYS L O    1 
ATOM   6169 C CB   . LYS B 2 196 ? 20.92286  7.28549   -19.47785 1.000 33.43812  ? 190 LYS L CB   1 
ATOM   6170 C CG   . LYS B 2 196 ? 21.26068  6.62615   -20.82182 1.000 53.43444  ? 190 LYS L CG   1 
ATOM   6171 C CD   . LYS B 2 196 ? 20.03706  6.08983   -21.57535 1.000 59.93593  ? 190 LYS L CD   1 
ATOM   6172 C CE   . LYS B 2 196 ? 18.92881  7.13566   -21.71679 1.000 51.55583  ? 190 LYS L CE   1 
ATOM   6173 N NZ   . LYS B 2 196 ? 17.89630  6.74668   -22.71998 1.000 51.10931  ? 190 LYS L NZ   1 
ATOM   6174 H H    . LYS B 2 196 ? 18.54979  6.43337   -18.86648 1.000 28.01425  ? 190 LYS L H    1 
ATOM   6175 H HA   . LYS B 2 196 ? 21.05525  5.57409   -18.32936 1.000 26.60950  ? 190 LYS L HA   1 
ATOM   6176 H HB2  . LYS B 2 196 ? 20.22099  7.93436   -19.64291 1.000 40.13257  ? 190 LYS L HB2  1 
ATOM   6177 H HB3  . LYS B 2 196 ? 21.72421  7.73532   -19.16740 1.000 40.13257  ? 190 LYS L HB3  1 
ATOM   6178 H HG2  . LYS B 2 196 ? 21.69341  7.28159   -21.39107 1.000 64.12816  ? 190 LYS L HG2  1 
ATOM   6179 H HG3  . LYS B 2 196 ? 21.85875  5.87945   -20.66163 1.000 64.12816  ? 190 LYS L HG3  1 
ATOM   6180 H HD2  . LYS B 2 196 ? 20.30763  5.81679   -22.46593 1.000 71.92995  ? 190 LYS L HD2  1 
ATOM   6181 H HD3  . LYS B 2 196 ? 19.67414  5.33135   -21.09173 1.000 71.92995  ? 190 LYS L HD3  1 
ATOM   6182 H HE2  . LYS B 2 196 ? 18.48778  7.24754   -20.86013 1.000 61.87383  ? 190 LYS L HE2  1 
ATOM   6183 H HE3  . LYS B 2 196 ? 19.32102  7.97631   -22.00031 1.000 61.87383  ? 190 LYS L HE3  1 
ATOM   6184 H HZ1  . LYS B 2 196 ? 18.27025  6.65717   -23.52263 1.000 61.33801  ? 190 LYS L HZ1  1 
ATOM   6185 H HZ2  . LYS B 2 196 ? 17.52235  5.97319   -22.48767 1.000 61.33801  ? 190 LYS L HZ2  1 
ATOM   6186 H HZ3  . LYS B 2 196 ? 17.26402  7.37149   -22.76397 1.000 61.33801  ? 190 LYS L HZ3  1 
ATOM   6187 N N    . VAL B 2 197 ? 19.63068  8.03317   -16.81888 1.000 19.14009  ? 191 VAL L N    1 
ATOM   6188 C CA   . VAL B 2 197 ? 19.71846  8.93112   -15.67559 1.000 21.65353  ? 191 VAL L CA   1 
ATOM   6189 C C    . VAL B 2 197 ? 18.65274  8.55305   -14.66031 1.000 21.28158  ? 191 VAL L C    1 
ATOM   6190 O O    . VAL B 2 197 ? 17.46078  8.49651   -14.98689 1.000 19.73004  ? 191 VAL L O    1 
ATOM   6191 C CB   . VAL B 2 197 ? 19.55797  10.39994  -16.10283 1.000 24.89677  ? 191 VAL L CB   1 
ATOM   6192 C CG1  . VAL B 2 197 ? 19.69399  11.32942  -14.88784 1.000 24.50889  ? 191 VAL L CG1  1 
ATOM   6193 C CG2  . VAL B 2 197 ? 20.55813  10.73624  -17.19454 1.000 25.66656  ? 191 VAL L CG2  1 
ATOM   6194 H H    . VAL B 2 197 ? 18.96286  8.20005   -17.33441 1.000 22.97494  ? 191 VAL L H    1 
ATOM   6195 H HA   . VAL B 2 197 ? 20.58643  8.81639   -15.25801 1.000 25.99108  ? 191 VAL L HA   1 
ATOM   6196 H HB   . VAL B 2 197 ? 18.67075  10.54022  -16.46898 1.000 29.88296  ? 191 VAL L HB   1 
ATOM   6197 H HG11 . VAL B 2 197 ? 19.76372  12.24597  -15.19763 1.000 29.41751  ? 191 VAL L HG11 1 
ATOM   6198 H HG12 . VAL B 2 197 ? 18.91076  11.22937  -14.32443 1.000 29.41751  ? 191 VAL L HG12 1 
ATOM   6199 H HG13 . VAL B 2 197 ? 20.49141  11.08630  -14.39194 1.000 29.41751  ? 191 VAL L HG13 1 
ATOM   6200 H HG21 . VAL B 2 197 ? 20.57148  11.69727  -17.32547 1.000 30.80671  ? 191 VAL L HG21 1 
ATOM   6201 H HG22 . VAL B 2 197 ? 21.43682  10.42703  -16.92399 1.000 30.80671  ? 191 VAL L HG22 1 
ATOM   6202 H HG23 . VAL B 2 197 ? 20.29018  10.29427  -18.01537 1.000 30.80671  ? 191 VAL L HG23 1 
ATOM   6203 N N    . TYR B 2 198 ? 19.08247  8.32251   -13.42893 1.000 16.29605  ? 192 TYR L N    1 
ATOM   6204 C CA   . TYR B 2 198 ? 18.18978  8.01570   -12.32182 1.000 16.21329  ? 192 TYR L CA   1 
ATOM   6205 C C    . TYR B 2 198 ? 18.37927  9.08783   -11.26631 1.000 15.95215  ? 192 TYR L C    1 
ATOM   6206 O O    . TYR B 2 198 ? 19.51721  9.45707   -10.95630 1.000 17.99492  ? 192 TYR L O    1 
ATOM   6207 C CB   . TYR B 2 198 ? 18.48453  6.62852   -11.76228 1.000 17.37100  ? 192 TYR L CB   1 
ATOM   6208 C CG   . TYR B 2 198 ? 18.09016  5.54354   -12.72759 1.000 16.43834  ? 192 TYR L CG   1 
ATOM   6209 C CD1  . TYR B 2 198 ? 18.93243  5.17188   -13.77321 1.000 19.09513  ? 192 TYR L CD1  1 
ATOM   6210 C CD2  . TYR B 2 198 ? 16.86181  4.91583   -12.61935 1.000 14.90825  ? 192 TYR L CD2  1 
ATOM   6211 C CE1  . TYR B 2 198 ? 18.56238  4.18755   -14.66662 1.000 17.71267  ? 192 TYR L CE1  1 
ATOM   6212 C CE2  . TYR B 2 198 ? 16.48527  3.92972   -13.50409 1.000 18.23280  ? 192 TYR L CE2  1 
ATOM   6213 C CZ   . TYR B 2 198 ? 17.33551  3.57532   -14.53072 1.000 17.18084  ? 192 TYR L CZ   1 
ATOM   6214 O OH   . TYR B 2 198 ? 16.94372  2.59512   -15.40980 1.000 19.35815  ? 192 TYR L OH   1 
ATOM   6215 H H    . TYR B 2 198 ? 19.91212  8.33864   -13.20305 1.000 19.56210  ? 192 TYR L H    1 
ATOM   6216 H HA   . TYR B 2 198 ? 17.26240  8.02271   -12.60611 1.000 19.46278  ? 192 TYR L HA   1 
ATOM   6217 H HB2  . TYR B 2 198 ? 19.43533  6.54979   -11.58716 1.000 20.85203  ? 192 TYR L HB2  1 
ATOM   6218 H HB3  . TYR B 2 198 ? 17.98432  6.50218   -10.94086 1.000 20.85203  ? 192 TYR L HB3  1 
ATOM   6219 H HD1  . TYR B 2 198 ? 19.75580  5.59319   -13.87046 1.000 22.92100  ? 192 TYR L HD1  1 
ATOM   6220 H HD2  . TYR B 2 198 ? 16.28035  5.16411   -11.93733 1.000 17.89673  ? 192 TYR L HD2  1 
ATOM   6221 H HE1  . TYR B 2 198 ? 19.13644  3.93936   -15.35493 1.000 21.26204  ? 192 TYR L HE1  1 
ATOM   6222 H HE2  . TYR B 2 198 ? 15.66302  3.50554   -13.40988 1.000 21.88620  ? 192 TYR L HE2  1 
ATOM   6223 H HH   . TYR B 2 198 ? 17.54725  2.46129   -15.97852 1.000 23.23662  ? 192 TYR L HH   1 
ATOM   6224 N N    . ALA B 2 199 ? 17.27519  9.60388   -10.73502 1.000 19.37654  ? 193 ALA L N    1 
ATOM   6225 C CA   . ALA B 2 199 ? 17.36344  10.66903  -9.75205  1.000 16.81173  ? 193 ALA L CA   1 
ATOM   6226 C C    . ALA B 2 199 ? 16.28069  10.52507  -8.69876  1.000 18.42771  ? 193 ALA L C    1 
ATOM   6227 O O    . ALA B 2 199 ? 15.16857  10.06387  -8.97223  1.000 16.08480  ? 193 ALA L O    1 
ATOM   6228 C CB   . ALA B 2 199 ? 17.25877  12.04176  -10.41707 1.000 16.77310  ? 193 ALA L CB   1 
ATOM   6229 H H    . ALA B 2 199 ? 16.47502  9.35449   -10.92773 1.000 23.25868  ? 193 ALA L H    1 
ATOM   6230 H HA   . ALA B 2 199 ? 18.21562  10.59996  -9.29387  1.000 20.18091  ? 193 ALA L HA   1 
ATOM   6231 H HB1  . ALA B 2 199 ? 17.35022  12.72908  -9.73874  1.000 20.13455  ? 193 ALA L HB1  1 
ATOM   6232 H HB2  . ALA B 2 199 ? 17.96695  12.12917  -11.07414 1.000 20.13455  ? 193 ALA L HB2  1 
ATOM   6233 H HB3  . ALA B 2 199 ? 16.39427  12.11764  -10.85041 1.000 20.13455  ? 193 ALA L HB3  1 
ATOM   6234 N N    . CYS B 2 200 ? 16.63104  10.91810  -7.48068  1.000 15.30253  ? 194 CYS L N    1 
ATOM   6235 C CA   A CYS B 2 200 ? 15.71062  11.00156  -6.35539  0.464 19.81395  ? 194 CYS L CA   1 
ATOM   6236 C CA   B CYS B 2 200 ? 15.66022  11.02013  -6.40350  0.536 20.09801  ? 194 CYS L CA   1 
ATOM   6237 C C    . CYS B 2 200 ? 15.66360  12.44999  -5.88803  1.000 19.26358  ? 194 CYS L C    1 
ATOM   6238 O O    . CYS B 2 200 ? 16.71766  13.02524  -5.57107  1.000 16.97922  ? 194 CYS L O    1 
ATOM   6239 C CB   A CYS B 2 200 ? 16.17934  10.07040  -5.23948  0.464 19.12611  ? 194 CYS L CB   1 
ATOM   6240 C CB   B CYS B 2 200 ? 15.89562  10.01014  -5.26683  0.536 19.22958  ? 194 CYS L CB   1 
ATOM   6241 S SG   A CYS B 2 200 ? 15.45201  10.32528  -3.62996  0.464 23.32962  ? 194 CYS L SG   1 
ATOM   6242 S SG   B CYS B 2 200 ? 17.37503  10.14540  -4.24872  0.536 21.61433  ? 194 CYS L SG   1 
ATOM   6243 H H    A CYS B 2 200 ? 17.43214  11.15181  -7.27278  0.464 18.36987  ? 194 CYS L H    1 
ATOM   6244 H H    B CYS B 2 200 ? 17.43243  11.13243  -7.25389  0.536 18.36987  ? 194 CYS L H    1 
ATOM   6245 H HA   A CYS B 2 200 ? 14.81278  10.74428  -6.61728  0.464 23.78358  ? 194 CYS L HA   1 
ATOM   6246 H HA   B CYS B 2 200 ? 14.77955  10.81355  -6.75370  0.536 24.12444  ? 194 CYS L HA   1 
ATOM   6247 H HB2  A CYS B 2 200 ? 15.97549  9.15926   -5.50247  0.464 22.95816  ? 194 CYS L HB2  1 
ATOM   6248 H HB2  B CYS B 2 200 ? 15.14201  10.07769  -4.65986  0.536 23.08233  ? 194 CYS L HB2  1 
ATOM   6249 H HB3  A CYS B 2 200 ? 17.13785  10.18010  -5.13887  0.464 22.95816  ? 194 CYS L HB3  1 
ATOM   6250 H HB3  B CYS B 2 200 ? 15.92163  9.12663   -5.66638  0.536 23.08233  ? 194 CYS L HB3  1 
ATOM   6251 N N    . GLU B 2 201 ? 14.46982  13.02617  -5.86248  1.000 18.12961  ? 195 GLU L N    1 
ATOM   6252 C CA   . GLU B 2 201 ? 14.22476  14.39869  -5.45714  1.000 19.08945  ? 195 GLU L CA   1 
ATOM   6253 C C    . GLU B 2 201 ? 13.52827  14.37213  -4.10891  1.000 18.52808  ? 195 GLU L C    1 
ATOM   6254 O O    . GLU B 2 201 ? 12.53223  13.66695  -3.93367  1.000 19.58753  ? 195 GLU L O    1 
ATOM   6255 C CB   . GLU B 2 201 ? 13.36062  15.11395  -6.49370  1.000 20.44820  ? 195 GLU L CB   1 
ATOM   6256 C CG   . GLU B 2 201 ? 13.02685  16.56348  -6.17851  1.000 25.76132  ? 195 GLU L CG   1 
ATOM   6257 C CD   . GLU B 2 201 ? 11.87107  17.07308  -7.01995  1.000 37.78817  ? 195 GLU L CD   1 
ATOM   6258 O OE1  . GLU B 2 201 ? 10.76150  16.50492  -6.91304  1.000 34.03978  ? 195 GLU L OE1  1 
ATOM   6259 O OE2  . GLU B 2 201 ? 12.07511  18.02574  -7.80021  1.000 47.06180  ? 195 GLU L OE2  1 
ATOM   6260 H H    . GLU B 2 201 ? 13.74748  12.61783  -6.08850  1.000 21.76237  ? 195 GLU L H    1 
ATOM   6261 H HA   . GLU B 2 201 ? 15.05760  14.88852  -5.37148  1.000 22.91418  ? 195 GLU L HA   1 
ATOM   6262 H HB2  . GLU B 2 201 ? 13.83059  15.10370  -7.34219  1.000 24.54468  ? 195 GLU L HB2  1 
ATOM   6263 H HB3  . GLU B 2 201 ? 12.52090  14.63504  -6.57376  1.000 24.54468  ? 195 GLU L HB3  1 
ATOM   6264 H HG2  . GLU B 2 201 ? 12.77822  16.63819  -5.24390  1.000 30.92041  ? 195 GLU L HG2  1 
ATOM   6265 H HG3  . GLU B 2 201 ? 13.80238  17.11687  -6.36076  1.000 30.92041  ? 195 GLU L HG3  1 
ATOM   6266 N N    . VAL B 2 202 ? 14.06232  15.12710  -3.16121  1.000 17.97081  ? 196 VAL L N    1 
ATOM   6267 C CA   . VAL B 2 202 ? 13.55314  15.19358  -1.80077  1.000 19.25216  ? 196 VAL L CA   1 
ATOM   6268 C C    . VAL B 2 202 ? 13.10563  16.62239  -1.56172  1.000 22.36847  ? 196 VAL L C    1 
ATOM   6269 O O    . VAL B 2 202 ? 13.90998  17.55361  -1.68423  1.000 19.31604  ? 196 VAL L O    1 
ATOM   6270 C CB   . VAL B 2 202 ? 14.62098  14.77931  -0.77552  1.000 20.86607  ? 196 VAL L CB   1 
ATOM   6271 C CG1  . VAL B 2 202 ? 14.05940  14.85533  0.63282   1.000 22.49315  ? 196 VAL L CG1  1 
ATOM   6272 C CG2  . VAL B 2 202 ? 15.13368  13.38696  -1.09172  1.000 22.83713  ? 196 VAL L CG2  1 
ATOM   6273 H H    . VAL B 2 202 ? 14.74828  15.63019  -3.28752  1.000 21.57181  ? 196 VAL L H    1 
ATOM   6274 H HA   . VAL B 2 202 ? 12.79013  14.60260  -1.70356  1.000 23.10943  ? 196 VAL L HA   1 
ATOM   6275 H HB   . VAL B 2 202 ? 15.37177  15.39153  -0.82455  1.000 25.04612  ? 196 VAL L HB   1 
ATOM   6276 H HG11 . VAL B 2 202 ? 14.68257  14.43297  1.24452   1.000 26.99862  ? 196 VAL L HG11 1 
ATOM   6277 H HG12 . VAL B 2 202 ? 13.93844  15.78686  0.87472   1.000 26.99862  ? 196 VAL L HG12 1 
ATOM   6278 H HG13 . VAL B 2 202 ? 13.20672  14.39359  0.65815   1.000 26.99862  ? 196 VAL L HG13 1 
ATOM   6279 H HG21 . VAL B 2 202 ? 15.75240  13.11287  -0.39677  1.000 27.41139  ? 196 VAL L HG21 1 
ATOM   6280 H HG22 . VAL B 2 202 ? 14.38256  12.77416  -1.12637  1.000 27.41139  ? 196 VAL L HG22 1 
ATOM   6281 H HG23 . VAL B 2 202 ? 15.58625  13.40432  -1.94949  1.000 27.41139  ? 196 VAL L HG23 1 
ATOM   6282 N N    . THR B 2 203 ? 11.83365  16.79241  -1.22448  1.000 19.72634  ? 197 THR L N    1 
ATOM   6283 C CA   . THR B 2 203 ? 11.23516  18.09581  -0.98743  1.000 20.02996  ? 197 THR L CA   1 
ATOM   6284 C C    . THR B 2 203 ? 10.81303  18.18664  0.46827   1.000 26.23047  ? 197 THR L C    1 
ATOM   6285 O O    . THR B 2 203 ? 10.10512  17.30113  0.97635   1.000 23.61947  ? 197 THR L O    1 
ATOM   6286 C CB   . THR B 2 203 ? 10.03705  18.32659  -1.91482  1.000 29.58935  ? 197 THR L CB   1 
ATOM   6287 O OG1  . THR B 2 203 ? 10.46740  18.22419  -3.27729  1.000 26.22293  ? 197 THR L OG1  1 
ATOM   6288 C CG2  . THR B 2 203 ? 9.42656   19.70684  -1.68863  1.000 29.59044  ? 197 THR L CG2  1 
ATOM   6289 H H    . THR B 2 203 ? 11.27871  16.14319  -1.12369  1.000 23.67844  ? 197 THR L H    1 
ATOM   6290 H HA   . THR B 2 203 ? 11.88527  18.79497  -1.15899  1.000 24.04278  ? 197 THR L HA   1 
ATOM   6291 H HB   . THR B 2 203 ? 9.35636   17.66087  -1.72942  1.000 35.51405  ? 197 THR L HB   1 
ATOM   6292 H HG1  . THR B 2 203 ? 11.05913  18.79897  -3.43564  1.000 31.47436  ? 197 THR L HG1  1 
ATOM   6293 H HG21 . THR B 2 203 ? 8.76342   19.89230  -2.37182  1.000 35.51536  ? 197 THR L HG21 1 
ATOM   6294 H HG22 . THR B 2 203 ? 9.00012   19.74238  -0.81812  1.000 35.51536  ? 197 THR L HG22 1 
ATOM   6295 H HG23 . THR B 2 203 ? 10.11798  20.38599  -1.72843  1.000 35.51536  ? 197 THR L HG23 1 
ATOM   6296 N N    . GLN B 2 204 ? 11.28546  19.24627  1.12797   1.000 26.63131  ? 198 GLN L N    1 
ATOM   6297 C CA   . GLN B 2 204 ? 10.97794  19.56097  2.51690   1.000 27.86328  ? 198 GLN L CA   1 
ATOM   6298 C C    . GLN B 2 204 ? 10.79827  21.06980  2.58838   1.000 28.46573  ? 198 GLN L C    1 
ATOM   6299 O O    . GLN B 2 204 ? 11.74046  21.81923  2.30418   1.000 27.44034  ? 198 GLN L O    1 
ATOM   6300 C CB   . GLN B 2 204 ? 12.10288  19.09293  3.44845   1.000 33.53355  ? 198 GLN L CB   1 
ATOM   6301 C CG   . GLN B 2 204 ? 11.82540  19.26745  4.92784   1.000 42.14016  ? 198 GLN L CG   1 
ATOM   6302 C CD   . GLN B 2 204 ? 13.08413  19.14074  5.77716   1.000 37.53752  ? 198 GLN L CD   1 
ATOM   6303 O OE1  . GLN B 2 204 ? 14.02109  19.93119  5.64576   1.000 37.61207  ? 198 GLN L OE1  1 
ATOM   6304 N NE2  . GLN B 2 204 ? 13.10880  18.14408  6.65104   1.000 30.57644  ? 198 GLN L NE2  1 
ATOM   6305 H H    . GLN B 2 204 ? 11.81245  19.82475  0.77125   1.000 31.96441  ? 198 GLN L H    1 
ATOM   6306 H HA   . GLN B 2 204 ? 10.16084  19.12386  2.80358   1.000 33.44277  ? 198 GLN L HA   1 
ATOM   6307 H HB2  . GLN B 2 204 ? 12.25819  18.14842  3.29138   1.000 40.24709  ? 198 GLN L HB2  1 
ATOM   6308 H HB3  . GLN B 2 204 ? 12.90356  19.59976  3.24122   1.000 40.24709  ? 198 GLN L HB3  1 
ATOM   6309 H HG2  . GLN B 2 204 ? 11.44868  20.14863  5.07785   1.000 50.57503  ? 198 GLN L HG2  1 
ATOM   6310 H HG3  . GLN B 2 204 ? 11.19854  18.58532  5.21534   1.000 50.57503  ? 198 GLN L HG3  1 
ATOM   6311 H HE21 . GLN B 2 204 ? 12.43656  17.61153  6.71500   1.000 36.69856  ? 198 GLN L HE21 1 
ATOM   6312 H HE22 . GLN B 2 204 ? 13.79704  18.03011  7.15397   1.000 36.69856  ? 198 GLN L HE22 1 
ATOM   6313 N N    . GLY B 2 205 ? 9.59209   21.51247  2.91566   1.000 30.16191  ? 199 GLY L N    1 
ATOM   6314 C CA   . GLY B 2 205 ? 9.34020   22.94211  3.00737   1.000 26.30993  ? 199 GLY L CA   1 
ATOM   6315 C C    . GLY B 2 205 ? 9.71481   23.65189  1.71830   1.000 26.11639  ? 199 GLY L C    1 
ATOM   6316 O O    . GLY B 2 205 ? 9.21149   23.33205  0.63477   1.000 28.67442  ? 199 GLY L O    1 
ATOM   6317 H H    . GLY B 2 205 ? 8.91232   21.01434  3.08704   1.000 36.20113  ? 199 GLY L H    1 
ATOM   6318 H HA2  . GLY B 2 205 ? 8.39894   23.09643  3.18375   1.000 31.57876  ? 199 GLY L HA2  1 
ATOM   6319 H HA3  . GLY B 2 205 ? 9.86327   23.31926  3.73199   1.000 31.57876  ? 199 GLY L HA3  1 
ATOM   6320 N N    . THR B 2 206 ? 10.61882  24.62262  1.82036   1.000 29.68755  ? 200 THR L N    1 
ATOM   6321 C CA   . THR B 2 206 ? 10.99686  25.45735  0.68896   1.000 31.33645  ? 200 THR L CA   1 
ATOM   6322 C C    . THR B 2 206 ? 12.21418  24.93391  -0.06164  1.000 30.54177  ? 200 THR L C    1 
ATOM   6323 O O    . THR B 2 206 ? 12.71663  25.62557  -0.95572  1.000 24.59395  ? 200 THR L O    1 
ATOM   6324 C CB   . THR B 2 206 ? 11.28035  26.88692  1.15976   1.000 35.29252  ? 200 THR L CB   1 
ATOM   6325 O OG1  . THR B 2 206 ? 12.33501  26.87217  2.13318   1.000 37.45875  ? 200 THR L OG1  1 
ATOM   6326 C CG2  . THR B 2 206 ? 10.03180  27.50796  1.76248   1.000 31.36217  ? 200 THR L CG2  1 
ATOM   6327 H H    . THR B 2 206 ? 11.03300  24.81865  2.54812   1.000 35.63189  ? 200 THR L H    1 
ATOM   6328 H HA   . THR B 2 206 ? 10.24859  25.47697  0.07202   1.000 37.61058  ? 200 THR L HA   1 
ATOM   6329 H HB   . THR B 2 206 ? 11.55169  27.43118  0.40408   1.000 42.35785  ? 200 THR L HB   1 
ATOM   6330 H HG1  . THR B 2 206 ? 12.51516  27.65664  2.37350   1.000 44.95733  ? 200 THR L HG1  1 
ATOM   6331 H HG21 . THR B 2 206 ? 10.20638  28.42916  2.01112   1.000 37.64144  ? 200 THR L HG21 1 
ATOM   6332 H HG22 . THR B 2 206 ? 9.30703   27.48775  1.11813   1.000 37.64144  ? 200 THR L HG22 1 
ATOM   6333 H HG23 . THR B 2 206 ? 9.76401   27.01385  2.55308   1.000 37.64144  ? 200 THR L HG23 1 
ATOM   6334 N N    . THR B 2 207 ? 12.70527  23.74520  0.27956   1.000 27.55484  ? 201 THR L N    1 
ATOM   6335 C CA   . THR B 2 207 ? 13.90460  23.19792  -0.33842  1.000 29.22311  ? 201 THR L CA   1 
ATOM   6336 C C    . THR B 2 207 ? 13.56726  21.90975  -1.07210  1.000 27.07645  ? 201 THR L C    1 
ATOM   6337 O O    . THR B 2 207 ? 12.84491  21.05430  -0.54522  1.000 23.26674  ? 201 THR L O    1 
ATOM   6338 C CB   . THR B 2 207 ? 14.99951  22.93014  0.70211   1.000 32.94911  ? 201 THR L CB   1 
ATOM   6339 O OG1  . THR B 2 207 ? 15.39831  24.16209  1.30912   1.000 37.89742  ? 201 THR L OG1  1 
ATOM   6340 C CG2  . THR B 2 207 ? 16.21723  22.27851  0.04994   1.000 33.54483  ? 201 THR L CG2  1 
ATOM   6341 H H    . THR B 2 207 ? 12.35476  23.23258  0.87451   1.000 33.07265  ? 201 THR L H    1 
ATOM   6342 H HA   . THR B 2 207 ? 14.24083  23.83868  -0.98438  1.000 35.07456  ? 201 THR L HA   1 
ATOM   6343 H HB   . THR B 2 207 ? 14.65482  22.32835  1.38030   1.000 39.54576  ? 201 THR L HB   1 
ATOM   6344 H HG1  . THR B 2 207 ? 16.01738  24.02386  1.85980   1.000 45.48374  ? 201 THR L HG1  1 
ATOM   6345 H HG21 . THR B 2 207 ? 16.98333  22.34032  0.64169   1.000 40.26063  ? 201 THR L HG21 1 
ATOM   6346 H HG22 . THR B 2 207 ? 16.03515  21.34341  -0.13267  1.000 40.26063  ? 201 THR L HG22 1 
ATOM   6347 H HG23 . THR B 2 207 ? 16.42672  22.72716  -0.78416  1.000 40.26063  ? 201 THR L HG23 1 
ATOM   6348 N N    . SER B 2 208 ? 14.07919  21.78693  -2.29319  1.000 22.54631  ? 202 SER L N    1 
ATOM   6349 C CA   . SER B 2 208 ? 14.10528  20.52985  -3.02700  1.000 23.98159  ? 202 SER L CA   1 
ATOM   6350 C C    . SER B 2 208 ? 15.55457  20.22008  -3.36633  1.000 24.80598  ? 202 SER L C    1 
ATOM   6351 O O    . SER B 2 208 ? 16.27933  21.08948  -3.85739  1.000 22.45692  ? 202 SER L O    1 
ATOM   6352 C CB   . SER B 2 208 ? 13.26334  20.59544  -4.30257  1.000 29.13828  ? 202 SER L CB   1 
ATOM   6353 O OG   . SER B 2 208 ? 11.88357  20.68161  -4.00124  1.000 37.15709  ? 202 SER L OG   1 
ATOM   6354 H H    . SER B 2 208 ? 14.42819  22.44052  -2.72978  1.000 27.06241  ? 202 SER L H    1 
ATOM   6355 H HA   . SER B 2 208 ? 13.73995  19.81840  -2.47811  1.000 28.78474  ? 202 SER L HA   1 
ATOM   6356 H HB2  . SER B 2 208 ? 13.52359  21.37947  -4.81097  1.000 34.97277  ? 202 SER L HB2  1 
ATOM   6357 H HB3  . SER B 2 208 ? 13.42147  19.79367  -4.82511  1.000 34.97277  ? 202 SER L HB3  1 
ATOM   6358 H HG   . SER B 2 208 ? 11.43506  20.70031  -4.71123  1.000 44.59534  ? 202 SER L HG   1 
ATOM   6359 N N    . VAL B 2 209 ? 15.97646  18.99564  -3.08546  1.000 18.74912  ? 203 VAL L N    1 
ATOM   6360 C CA   . VAL B 2 209 ? 17.32232  18.53050  -3.39064  1.000 19.48524  ? 203 VAL L CA   1 
ATOM   6361 C C    . VAL B 2 209 ? 17.20360  17.27227  -4.23288  1.000 22.79976  ? 203 VAL L C    1 
ATOM   6362 O O    . VAL B 2 209 ? 16.49320  16.34084  -3.85431  1.000 16.90692  ? 203 VAL L O    1 
ATOM   6363 C CB   . VAL B 2 209 ? 18.12059  18.24763  -2.10743  1.000 21.37874  ? 203 VAL L CB   1 
ATOM   6364 C CG1  . VAL B 2 209 ? 19.54640  17.82136  -2.45144  1.000 30.91170  ? 203 VAL L CG1  1 
ATOM   6365 C CG2  . VAL B 2 209 ? 18.11131  19.46194  -1.20942  1.000 30.00112  ? 203 VAL L CG2  1 
ATOM   6366 H H    . VAL B 2 209 ? 15.48700  18.39837  -2.70692  1.000 22.50578  ? 203 VAL L H    1 
ATOM   6367 H HA   . VAL B 2 209 ? 17.79194  19.20556  -3.90508  1.000 23.38913  ? 203 VAL L HA   1 
ATOM   6368 H HB   . VAL B 2 209 ? 17.70455  17.51737  -1.62315  1.000 25.66132  ? 203 VAL L HB   1 
ATOM   6369 H HG11 . VAL B 2 209 ? 20.07179  17.78961  -1.63667  1.000 37.10087  ? 203 VAL L HG11 1 
ATOM   6370 H HG12 . VAL B 2 209 ? 19.52278  16.94388  -2.86419  1.000 37.10087  ? 203 VAL L HG12 1 
ATOM   6371 H HG13 . VAL B 2 209 ? 19.92901  18.46618  -3.06683  1.000 37.10087  ? 203 VAL L HG13 1 
ATOM   6372 H HG21 . VAL B 2 209 ? 18.72371  19.31397  -0.47188  1.000 36.00818  ? 203 VAL L HG21 1 
ATOM   6373 H HG22 . VAL B 2 209 ? 18.39194  20.23605  -1.72216  1.000 36.00818  ? 203 VAL L HG22 1 
ATOM   6374 H HG23 . VAL B 2 209 ? 17.21246  19.59752  -0.87091  1.000 36.00818  ? 203 VAL L HG23 1 
ATOM   6375 N N    . THR B 2 210 ? 17.89321  17.23773  -5.36571  1.000 18.27242  ? 204 THR L N    1 
ATOM   6376 C CA   . THR B 2 210 ? 17.86641  16.07813  -6.24328  1.000 19.41994  ? 204 THR L CA   1 
ATOM   6377 C C    . THR B 2 210 ? 19.26538  15.50231  -6.36633  1.000 20.41211  ? 204 THR L C    1 
ATOM   6378 O O    . THR B 2 210 ? 20.21430  16.22908  -6.68126  1.000 20.51349  ? 204 THR L O    1 
ATOM   6379 C CB   . THR B 2 210 ? 17.32866  16.43800  -7.62922  1.000 21.90644  ? 204 THR L CB   1 
ATOM   6380 O OG1  . THR B 2 210 ? 16.06002  17.09068  -7.50013  1.000 20.46160  ? 204 THR L OG1  1 
ATOM   6381 C CG2  . THR B 2 210 ? 17.15544  15.18837  -8.46670  1.000 22.74797  ? 204 THR L CG2  1 
ATOM   6382 H H    . THR B 2 210 ? 18.38857  17.88112  -5.64902  1.000 21.93374  ? 204 THR L H    1 
ATOM   6383 H HA   . THR B 2 210 ? 17.28779  15.40297  -5.85567  1.000 23.31076  ? 204 THR L HA   1 
ATOM   6384 H HB   . THR B 2 210 ? 17.95514  17.02960  -8.07466  1.000 26.29456  ? 204 THR L HB   1 
ATOM   6385 H HG1  . THR B 2 210 ? 15.75293  17.27464  -8.26003  1.000 24.56076  ? 204 THR L HG1  1 
ATOM   6386 H HG21 . THR B 2 210 ? 16.70045  15.40490  -9.29555  1.000 27.30440  ? 204 THR L HG21 1 
ATOM   6387 H HG22 . THR B 2 210 ? 18.02210  14.80524  -8.67413  1.000 27.30440  ? 204 THR L HG22 1 
ATOM   6388 H HG23 . THR B 2 210 ? 16.62993  14.53361  -7.98087  1.000 27.30440  ? 204 THR L HG23 1 
ATOM   6389 N N    . LYS B 2 211 ? 19.38515  14.19951  -6.11978  1.000 16.30467  ? 205 LYS L N    1 
ATOM   6390 C CA   . LYS B 2 211 ? 20.62481  13.45938  -6.31835  1.000 16.57080  ? 205 LYS L CA   1 
ATOM   6391 C C    . LYS B 2 211 ? 20.42769  12.48877  -7.47413  1.000 19.78612  ? 205 LYS L C    1 
ATOM   6392 O O    . LYS B 2 211 ? 19.41616  11.77983  -7.53029  1.000 16.43352  ? 205 LYS L O    1 
ATOM   6393 C CB   . LYS B 2 211 ? 21.02722  12.69146  -5.05838  1.000 20.88561  ? 205 LYS L CB   1 
ATOM   6394 C CG   . LYS B 2 211 ? 21.40625  13.55904  -3.86903  1.000 22.85511  ? 205 LYS L CG   1 
ATOM   6395 C CD   . LYS B 2 211 ? 22.84256  14.02997  -3.96073  1.000 24.01015  ? 205 LYS L CD   1 
ATOM   6396 C CE   . LYS B 2 211 ? 23.21190  14.93385  -2.78973  1.000 35.50626  ? 205 LYS L CE   1 
ATOM   6397 N NZ   . LYS B 2 211 ? 24.65853  15.32629  -2.81015  1.000 48.79265  ? 205 LYS L NZ   1 
ATOM   6398 H H    . LYS B 2 211 ? 18.74123  13.70980  -5.82798  1.000 19.57244  ? 205 LYS L H    1 
ATOM   6399 H HA   . LYS B 2 211 ? 21.34169  14.07644  -6.53332  1.000 19.89180  ? 205 LYS L HA   1 
ATOM   6400 H HB2  . LYS B 2 211 ? 20.28028  12.13564  -4.78626  1.000 25.06957  ? 205 LYS L HB2  1 
ATOM   6401 H HB3  . LYS B 2 211 ? 21.79424  12.13641  -5.26931  1.000 25.06957  ? 205 LYS L HB3  1 
ATOM   6402 H HG2  . LYS B 2 211 ? 20.83061  14.33937  -3.84414  1.000 27.43297  ? 205 LYS L HG2  1 
ATOM   6403 H HG3  . LYS B 2 211 ? 21.30524  13.04606  -3.05199  1.000 27.43297  ? 205 LYS L HG3  1 
ATOM   6404 H HD2  . LYS B 2 211 ? 23.43381  13.26107  -3.95026  1.000 28.81902  ? 205 LYS L HD2  1 
ATOM   6405 H HD3  . LYS B 2 211 ? 22.96432  14.53094  -4.78238  1.000 28.81902  ? 205 LYS L HD3  1 
ATOM   6406 H HE2  . LYS B 2 211 ? 22.67890  15.74319  -2.83192  1.000 42.61435  ? 205 LYS L HE2  1 
ATOM   6407 H HE3  . LYS B 2 211 ? 23.03797  14.46502  -1.95856  1.000 42.61435  ? 205 LYS L HE3  1 
ATOM   6408 H HZ1  . LYS B 2 211 ? 24.83967  15.85725  -2.11923  1.000 58.55802  ? 205 LYS L HZ1  1 
ATOM   6409 H HZ2  . LYS B 2 211 ? 25.17149  14.60078  -2.75914  1.000 58.55802  ? 205 LYS L HZ2  1 
ATOM   6410 H HZ3  . LYS B 2 211 ? 24.84568  15.75990  -3.56450  1.000 58.55802  ? 205 LYS L HZ3  1 
ATOM   6411 N N    . SER B 2 212 ? 21.39171  12.44461  -8.38499  1.000 18.64056  ? 206 SER L N    1 
ATOM   6412 C CA   . SER B 2 212 ? 21.24690  11.63100  -9.57809  1.000 18.34261  ? 206 SER L CA   1 
ATOM   6413 C C    . SER B 2 212 ? 22.52582  10.86050  -9.85786  1.000 17.67188  ? 206 SER L C    1 
ATOM   6414 O O    . SER B 2 212 ? 23.59187  11.13544  -9.30054  1.000 18.06897  ? 206 SER L O    1 
ATOM   6415 C CB   . SER B 2 212 ? 20.89202  12.48816  -10.79524 1.000 20.87460  ? 206 SER L CB   1 
ATOM   6416 O OG   . SER B 2 212 ? 21.91937  13.42750  -11.04375 1.000 21.24145  ? 206 SER L OG   1 
ATOM   6417 H H    . SER B 2 212 ? 22.13400  12.87569  -8.33230  1.000 22.37551  ? 206 SER L H    1 
ATOM   6418 H HA   . SER B 2 212 ? 20.54077  10.98619  -9.41527  1.000 22.01796  ? 206 SER L HA   1 
ATOM   6419 H HB2  . SER B 2 212 ? 20.79040  11.91425  -11.57062 1.000 25.05636  ? 206 SER L HB2  1 
ATOM   6420 H HB3  . SER B 2 212 ? 20.06302  12.96088  -10.62146 1.000 25.05636  ? 206 SER L HB3  1 
ATOM   6421 H HG   . SER B 2 212 ? 21.71377  13.91157  -11.69874 1.000 25.49658  ? 206 SER L HG   1 
ATOM   6422 N N    . PHE B 2 213 ? 22.38967  9.87895   -10.74338 1.000 18.47847  ? 207 PHE L N    1 
ATOM   6423 C CA   . PHE B 2 213 ? 23.52746  9.16373   -11.29630 1.000 18.81806  ? 207 PHE L CA   1 
ATOM   6424 C C    . PHE B 2 213 ? 23.17447  8.69965   -12.70189 1.000 21.18846  ? 207 PHE L C    1 
ATOM   6425 O O    . PHE B 2 213 ? 21.99833  8.50892   -13.03865 1.000 17.92996  ? 207 PHE L O    1 
ATOM   6426 C CB   . PHE B 2 213 ? 23.94196  7.97097   -10.42119 1.000 20.69562  ? 207 PHE L CB   1 
ATOM   6427 C CG   . PHE B 2 213 ? 22.96573  6.82739   -10.43001 1.000 16.90850  ? 207 PHE L CG   1 
ATOM   6428 C CD1  . PHE B 2 213 ? 23.01347  5.86140   -11.42359 1.000 18.94784  ? 207 PHE L CD1  1 
ATOM   6429 C CD2  . PHE B 2 213 ? 22.01865  6.69806   -9.42525  1.000 17.01828  ? 207 PHE L CD2  1 
ATOM   6430 C CE1  . PHE B 2 213 ? 22.12127  4.81013   -11.42620 1.000 20.59584  ? 207 PHE L CE1  1 
ATOM   6431 C CE2  . PHE B 2 213 ? 21.12597  5.64828   -9.42585  1.000 16.38815  ? 207 PHE L CE2  1 
ATOM   6432 C CZ   . PHE B 2 213 ? 21.17664  4.70162   -10.42123 1.000 19.18792  ? 207 PHE L CZ   1 
ATOM   6433 H H    . PHE B 2 213 ? 21.63217  9.60479   -11.04441 1.000 22.18100  ? 207 PHE L H    1 
ATOM   6434 H HA   . PHE B 2 213 ? 24.28897  9.76188   -11.35304 1.000 22.58851  ? 207 PHE L HA   1 
ATOM   6435 H HB2  . PHE B 2 213 ? 24.79298  7.63301   -10.74127 1.000 24.84158  ? 207 PHE L HB2  1 
ATOM   6436 H HB3  . PHE B 2 213 ? 24.02950  8.27522   -9.50431  1.000 24.84158  ? 207 PHE L HB3  1 
ATOM   6437 H HD1  . PHE B 2 213 ? 23.65385  5.92319   -12.09514 1.000 22.74424  ? 207 PHE L HD1  1 
ATOM   6438 H HD2  . PHE B 2 213 ? 21.98555  7.32813   -8.74201  1.000 20.42878  ? 207 PHE L HD2  1 
ATOM   6439 H HE1  . PHE B 2 213 ? 22.15450  4.17387   -12.10366 1.000 24.72184  ? 207 PHE L HE1  1 
ATOM   6440 H HE2  . PHE B 2 213 ? 20.48854  5.58019   -8.75210  1.000 19.67261  ? 207 PHE L HE2  1 
ATOM   6441 H HZ   . PHE B 2 213 ? 20.57764  3.99022   -10.41912 1.000 23.03234  ? 207 PHE L HZ   1 
ATOM   6442 N N    . ASN B 2 214 ? 24.21159  8.53195   -13.51873 1.000 20.76973  ? 208 ASN L N    1 
ATOM   6443 C CA   . ASN B 2 214 ? 24.09521  7.97321   -14.85850 1.000 27.43848  ? 208 ASN L CA   1 
ATOM   6444 C C    . ASN B 2 214 ? 24.50112  6.50842   -14.80601 1.000 25.40317  ? 208 ASN L C    1 
ATOM   6445 O O    . ASN B 2 214 ? 25.57377  6.17804   -14.28890 1.000 29.23270  ? 208 ASN L O    1 
ATOM   6446 C CB   . ASN B 2 214 ? 24.98555  8.72481   -15.84738 1.000 34.56416  ? 208 ASN L CB   1 
ATOM   6447 C CG   . ASN B 2 214 ? 24.75966  10.22035  -15.81587 1.000 43.46161  ? 208 ASN L CG   1 
ATOM   6448 O OD1  . ASN B 2 214 ? 23.63457  10.69669  -15.99041 1.000 38.32900  ? 208 ASN L OD1  1 
ATOM   6449 N ND2  . ASN B 2 214 ? 25.83100  10.97411  -15.57890 1.000 48.33836  ? 208 ASN L ND2  1 
ATOM   6450 H H    . ASN B 2 214 ? 25.01905  8.74209   -13.31028 1.000 24.93050  ? 208 ASN L H    1 
ATOM   6451 H HA   . ASN B 2 214 ? 23.17848  8.04380   -15.16757 1.000 32.93301  ? 208 ASN L HA   1 
ATOM   6452 H HB2  . ASN B 2 214 ? 25.91513  8.55688   -15.62698 1.000 41.48383  ? 208 ASN L HB2  1 
ATOM   6453 H HB3  . ASN B 2 214 ? 24.79567  8.41136   -16.74548 1.000 41.48383  ? 208 ASN L HB3  1 
ATOM   6454 H HD21 . ASN B 2 214 ? 25.75658  11.83042  -15.55062 1.000 58.01286  ? 208 ASN L HD21 1 
ATOM   6455 H HD22 . ASN B 2 214 ? 26.59756  10.60475  -15.45410 1.000 58.01286  ? 208 ASN L HD22 1 
ATOM   6456 N N    . ARG B 2 215 ? 23.64285  5.63929   -15.32701 1.000 25.33102  ? 209 ARG L N    1 
ATOM   6457 C CA   . ARG B 2 215 ? 23.90927  4.20775   -15.28417 1.000 28.58203  ? 209 ARG L CA   1 
ATOM   6458 C C    . ARG B 2 215 ? 25.22971  3.89933   -15.97802 1.000 32.03147  ? 209 ARG L C    1 
ATOM   6459 O O    . ARG B 2 215 ? 25.54347  4.46110   -17.03032 1.000 29.75769  ? 209 ARG L O    1 
ATOM   6460 C CB   . ARG B 2 215 ? 22.76306  3.43982   -15.94826 1.000 22.91417  ? 209 ARG L CB   1 
ATOM   6461 C CG   . ARG B 2 215 ? 22.95181  1.92985   -15.99601 1.000 27.42732  ? 209 ARG L CG   1 
ATOM   6462 C CD   . ARG B 2 215 ? 21.79460  1.24688   -16.69952 1.000 26.71248  ? 209 ARG L CD   1 
ATOM   6463 N NE   . ARG B 2 215 ? 21.46464  1.87932   -17.97053 1.000 26.85763  ? 209 ARG L NE   1 
ATOM   6464 C CZ   . ARG B 2 215 ? 22.07256  1.62710   -19.12288 1.000 32.24412  ? 209 ARG L CZ   1 
ATOM   6465 N NH1  . ARG B 2 215 ? 23.07700  0.76886   -19.20375 1.000 33.56163  ? 209 ARG L NH1  1 
ATOM   6466 N NH2  . ARG B 2 215 ? 21.65874  2.25024   -20.22281 1.000 35.14831  ? 209 ARG L NH2  1 
ATOM   6467 H H    . ARG B 2 215 ? 22.90228  5.85134   -15.70935 1.000 30.40406  ? 209 ARG L H    1 
ATOM   6468 H HA   . ARG B 2 215 ? 23.97284  3.91213   -14.36250 1.000 34.30527  ? 209 ARG L HA   1 
ATOM   6469 H HB2  . ARG B 2 215 ? 21.94704  3.61664   -15.45456 1.000 27.50384  ? 209 ARG L HB2  1 
ATOM   6470 H HB3  . ARG B 2 215 ? 22.67208  3.75179   -16.86221 1.000 27.50384  ? 209 ARG L HB3  1 
ATOM   6471 H HG2  . ARG B 2 215 ? 23.76711  1.72309   -16.47917 1.000 32.91962  ? 209 ARG L HG2  1 
ATOM   6472 H HG3  . ARG B 2 215 ? 23.00551  1.58401   -15.09136 1.000 32.91962  ? 209 ARG L HG3  1 
ATOM   6473 H HD2  . ARG B 2 215 ? 22.03089  0.32270   -16.87548 1.000 32.06181  ? 209 ARG L HD2  1 
ATOM   6474 H HD3  . ARG B 2 215 ? 21.00967  1.28614   -16.13096 1.000 32.06181  ? 209 ARG L HD3  1 
ATOM   6475 H HE   . ARG B 2 215 ? 20.82910  2.45870   -17.97396 1.000 32.23599  ? 209 ARG L HE   1 
ATOM   6476 H HH11 . ARG B 2 215 ? 23.35038  0.35921   -18.49873 1.000 40.28079  ? 209 ARG L HH11 1 
ATOM   6477 H HH12 . ARG B 2 215 ? 23.45622  0.62090   -19.96131 1.000 40.28079  ? 209 ARG L HH12 1 
ATOM   6478 H HH21 . ARG B 2 215 ? 21.00544  2.80797   -20.18107 1.000 42.18481  ? 209 ARG L HH21 1 
ATOM   6479 H HH22 . ARG B 2 215 ? 22.04449  2.09538   -20.97568 1.000 42.18481  ? 209 ARG L HH22 1 
ATOM   6480 N N    . GLY B 2 216 ? 26.01596  3.01269   -15.36831 1.000 39.26127  ? 210 GLY L N    1 
ATOM   6481 C CA   . GLY B 2 216 ? 27.27760  2.58780   -15.92737 1.000 53.76995  ? 210 GLY L CA   1 
ATOM   6482 C C    . GLY B 2 216 ? 28.47154  3.42764   -15.52691 1.000 58.39469  ? 210 GLY L C    1 
ATOM   6483 O O    . GLY B 2 216 ? 29.60955  2.96311   -15.65933 1.000 59.70590  ? 210 GLY L O    1 
ATOM   6484 H H    . GLY B 2 216 ? 25.82839  2.64130   -14.61566 1.000 47.12036  ? 210 GLY L H    1 
ATOM   6485 H HA2  . GLY B 2 216 ? 27.45030  1.67605   -15.64491 1.000 64.53078  ? 210 GLY L HA2  1 
ATOM   6486 H HA3  . GLY B 2 216 ? 27.21148  2.61154   -16.89483 1.000 64.53078  ? 210 GLY L HA3  1 
ATOM   6487 N N    . GLU B 2 217 ? 28.25181  4.65055   -15.05300 1.000 57.29890  ? 211 GLU L N    1 
ATOM   6488 C CA   . GLU B 2 217 ? 29.33899  5.45818   -14.52704 1.000 59.02094  ? 211 GLU L CA   1 
ATOM   6489 C C    . GLU B 2 217 ? 29.65230  5.01620   -13.09707 1.000 66.21273  ? 211 GLU L C    1 
ATOM   6490 O O    . GLU B 2 217 ? 29.01272  4.11839   -12.54101 1.000 64.79712  ? 211 GLU L O    1 
ATOM   6491 C CB   . GLU B 2 217 ? 28.98212  6.94100   -14.60626 1.000 55.13518  ? 211 GLU L CB   1 
ATOM   6492 C CG   . GLU B 2 217 ? 28.57436  7.39200   -16.00949 1.000 54.72475  ? 211 GLU L CG   1 
ATOM   6493 C CD   . GLU B 2 217 ? 28.68126  8.89635   -16.21503 1.000 59.90210  ? 211 GLU L CD   1 
ATOM   6494 O OE1  . GLU B 2 217 ? 29.12403  9.60278   -15.28288 1.000 60.92197  ? 211 GLU L OE1  1 
ATOM   6495 O OE2  . GLU B 2 217 ? 28.32007  9.37196   -17.31505 1.000 53.10061  ? 211 GLU L OE2  1 
ATOM   6496 H H    . GLU B 2 217 ? 27.48154  5.03209   -15.02642 1.000 68.76551  ? 211 GLU L H    1 
ATOM   6497 H HA   . GLU B 2 217 ? 30.13471  5.32503   -15.06555 1.000 70.83196  ? 211 GLU L HA   1 
ATOM   6498 H HB2  . GLU B 2 217 ? 28.23827  7.11666   -14.00899 1.000 66.16905  ? 211 GLU L HB2  1 
ATOM   6499 H HB3  . GLU B 2 217 ? 29.75378  7.46384   -14.33779 1.000 66.16905  ? 211 GLU L HB3  1 
ATOM   6500 H HG2  . GLU B 2 217 ? 29.15312  6.96143   -16.65798 1.000 65.67653  ? 211 GLU L HG2  1 
ATOM   6501 H HG3  . GLU B 2 217 ? 27.65210  7.13533   -16.16591 1.000 65.67653  ? 211 GLU L HG3  1 
ATOM   6502 N N    . CYS B 2 218 ? 30.65553  5.64640   -12.49300 1.000 76.62308  ? 212 CYS L N    1 
ATOM   6503 C CA   . CYS B 2 218 ? 31.13431  5.23094   -11.17568 1.000 88.61524  ? 212 CYS L CA   1 
ATOM   6504 C C    . CYS B 2 218 ? 31.42106  6.42507   -10.26877 1.000 77.37908  ? 212 CYS L C    1 
ATOM   6505 O O    . CYS B 2 218 ? 31.69776  7.52762   -10.74039 1.000 80.92119  ? 212 CYS L O    1 
ATOM   6506 C CB   . CYS B 2 218 ? 32.39576  4.37072   -11.31870 1.000 88.68009  ? 212 CYS L CB   1 
ATOM   6507 S SG   . CYS B 2 218 ? 32.10202  2.71580   -11.99774 1.000 105.67677 ? 212 CYS L SG   1 
ATOM   6508 H H    . CYS B 2 218 ? 31.07702  6.31866   -12.82469 1.000 91.95453  ? 212 CYS L H    1 
ATOM   6509 H HA   . CYS B 2 218 ? 30.44164  4.70231   -10.74945 1.000 106.34512 ? 212 CYS L HA   1 
ATOM   6510 H HB2  . CYS B 2 218 ? 33.01435  4.82546   -11.91154 1.000 106.42294 ? 212 CYS L HB2  1 
ATOM   6511 H HB3  . CYS B 2 218 ? 32.79620  4.26123   -10.44203 1.000 106.42294 ? 212 CYS L HB3  1 
ATOM   6512 H HG   . CYS B 2 218 ? 33.14779  2.13166   -12.06947 1.000 126.81896 ? 212 CYS L HG   1 
ATOM   6513 N N    . ALA C 3 3   ? -2.80688  -11.71797 49.93457  1.000 39.55495  ? 3   ALA C N    1 
ATOM   6514 C CA   . ALA C 3 3   ? -1.87982  -12.14824 48.89217  1.000 25.00028  ? 3   ALA C CA   1 
ATOM   6515 C C    . ALA C 3 3   ? -1.51248  -10.99207 47.97314  1.000 21.99143  ? 3   ALA C C    1 
ATOM   6516 O O    . ALA C 3 3   ? -2.32297  -10.09783 47.72388  1.000 27.13955  ? 3   ALA C O    1 
ATOM   6517 C CB   . ALA C 3 3   ? -2.48208  -13.29184 48.08571  1.000 28.36683  ? 3   ALA C CB   1 
ATOM   6518 H HA   . ALA C 3 3   ? -1.06609  -12.46879 49.31170  1.000 30.00717  ? 3   ALA C HA   1 
ATOM   6519 H HB1  . ALA C 3 3   ? -1.85056  -13.56218 47.40088  1.000 34.04702  ? 3   ALA C HB1  1 
ATOM   6520 H HB2  . ALA C 3 3   ? -2.66385  -14.03623 48.68047  1.000 34.04702  ? 3   ALA C HB2  1 
ATOM   6521 H HB3  . ALA C 3 3   ? -3.30638  -12.98828 47.67426  1.000 34.04702  ? 3   ALA C HB3  1 
ATOM   6522 N N    . GLY C 3 4   ? -0.28270  -11.01835 47.47130  1.000 28.11852  ? 4   GLY C N    1 
ATOM   6523 C CA   . GLY C 3 4   ? 0.20203   -9.99202  46.56970  1.000 27.36817  ? 4   GLY C CA   1 
ATOM   6524 C C    . GLY C 3 4   ? -0.40885  -10.08507 45.18366  1.000 21.57198  ? 4   GLY C C    1 
ATOM   6525 O O    . GLY C 3 4   ? -0.39245  -9.11772  44.42382  1.000 20.04141  ? 4   GLY C O    1 
ATOM   6526 H H    . GLY C 3 4   ? 0.29592   -11.63105 47.64276  1.000 33.74906  ? 4   GLY C H    1 
ATOM   6527 H HA2  . GLY C 3 4   ? -0.00987  -9.11951  46.93676  1.000 32.84864  ? 4   GLY C HA2  1 
ATOM   6528 H HA3  . GLY C 3 4   ? 1.16477   -10.07285 46.48306  1.000 32.84864  ? 4   GLY C HA3  1 
HETATM 6529 N N    . NEP C 3 5   ? -0.93631  -11.25439 44.84188  1.000 21.20398  ? 5   NEP C N    1 
HETATM 6530 C CA   . NEP C 3 5   ? -1.61881  -11.42136 43.58052  1.000 16.47964  ? 5   NEP C CA   1 
HETATM 6531 C C    . NEP C 3 5   ? -2.90789  -12.20082 43.82561  1.000 18.21692  ? 5   NEP C C    1 
HETATM 6532 O O    . NEP C 3 5   ? -3.16995  -12.79806 44.86937  1.000 21.31731  ? 5   NEP C O    1 
HETATM 6533 C CB   . NEP C 3 5   ? -0.78300  -12.14191 42.49471  1.000 20.00153  ? 5   NEP C CB   1 
HETATM 6534 C CG   . NEP C 3 5   ? 0.45911   -11.42079 42.13135  1.000 18.06838  ? 5   NEP C CG   1 
HETATM 6535 N ND1  . NEP C 3 5   ? 1.66920   -11.53617 42.85541  1.000 15.77616  ? 5   NEP C ND1  1 
HETATM 6536 C CD2  . NEP C 3 5   ? 0.66689   -10.53203 41.05580  1.000 16.66553  ? 5   NEP C CD2  1 
HETATM 6537 C CE1  . NEP C 3 5   ? 2.56098   -10.74194 42.24274  1.000 16.45486  ? 5   NEP C CE1  1 
HETATM 6538 N NE2  . NEP C 3 5   ? 2.01582   -10.09116 41.11510  1.000 16.70669  ? 5   NEP C NE2  1 
HETATM 6539 P P    . NEP C 3 5   ? 2.67949   -9.06141  40.07929  1.000 14.73566  ? 5   NEP C P    1 
HETATM 6540 O O1P  . NEP C 3 5   ? 3.27929   -7.83928  40.91630  1.000 15.31560  ? 5   NEP C O1P  1 
HETATM 6541 O O2P  . NEP C 3 5   ? 4.06765   -9.68341  39.61724  1.000 17.31324  ? 5   NEP C O2P  1 
HETATM 6542 O O3P  . NEP C 3 5   ? 1.81022   -8.54370  39.01967  1.000 16.24279  ? 5   NEP C O3P  1 
HETATM 6543 H HA   . NEP C 3 5   ? -1.94448  -10.42009 43.16208  1.000 19.78241  ? 5   NEP C HA   1 
HETATM 6544 H HB2  . NEP C 3 5   ? -1.40980  -12.26618 41.57001  1.000 24.00866  ? 5   NEP C HB2  1 
HETATM 6545 H HB3  . NEP C 3 5   ? -0.50822  -13.16791 42.86240  1.000 24.00866  ? 5   NEP C HB3  1 
HETATM 6546 H HD2  . NEP C 3 5   ? 0.01116   -10.16687 40.26124  1.000 20.00547  ? 5   NEP C HD2  1 
HETATM 6547 H HE1  . NEP C 3 5   ? 3.60172   -10.60069 42.56633  1.000 19.75267  ? 5   NEP C HE1  1 
ATOM   6548 N N    . ALA C 3 6   ? -3.76110  -12.16454 42.80754  1.000 14.64960  ? 6   ALA C N    1 
ATOM   6549 C CA   . ALA C 3 6   ? -4.99734  -12.93079 42.79244  1.000 16.43863  ? 6   ALA C CA   1 
ATOM   6550 C C    . ALA C 3 6   ? -4.68899  -14.38692 42.47277  1.000 22.41607  ? 6   ALA C C    1 
ATOM   6551 O O    . ALA C 3 6   ? -3.57330  -14.71133 42.06158  1.000 20.34254  ? 6   ALA C O    1 
ATOM   6552 C CB   . ALA C 3 6   ? -5.96154  -12.35462 41.77352  1.000 18.95489  ? 6   ALA C CB   1 
ATOM   6553 H H    . ALA C 3 6   ? -3.64258  -11.69259 42.09845  1.000 17.58636  ? 6   ALA C H    1 
ATOM   6554 H HA   . ALA C 3 6   ? -5.42762  -12.88323 43.66048  1.000 19.73319  ? 6   ALA C HA   1 
ATOM   6555 H HB1  . ALA C 3 6   ? -6.77935  -12.87617 41.78245  1.000 22.75270  ? 6   ALA C HB1  1 
ATOM   6556 H HB2  . ALA C 3 6   ? -6.15435  -11.43310 42.00704  1.000 22.75270  ? 6   ALA C HB2  1 
ATOM   6557 H HB3  . ALA C 3 6   ? -5.55329  -12.39464 40.89453  1.000 22.75270  ? 6   ALA C HB3  1 
ATOM   6558 N N    . GLY C 3 7   ? -5.68610  -15.25301 42.65252  1.000 16.98135  ? 7   GLY C N    1 
ATOM   6559 C CA   . GLY C 3 7   ? -5.54946  -16.66017 42.34769  1.000 18.58954  ? 7   GLY C CA   1 
ATOM   6560 C C    . GLY C 3 7   ? -4.75043  -17.47313 43.34056  1.000 22.16081  ? 7   GLY C C    1 
ATOM   6561 O O    . GLY C 3 7   ? -4.38644  -18.61336 43.03043  1.000 21.13784  ? 7   GLY C O    1 
ATOM   6562 H H    . GLY C 3 7   ? -6.46205  -15.03913 42.95545  1.000 20.38446  ? 7   GLY C H    1 
ATOM   6563 H HA2  . GLY C 3 7   ? -6.43591  -17.05071 42.29688  1.000 22.31428  ? 7   GLY C HA2  1 
ATOM   6564 H HA3  . GLY C 3 7   ? -5.11636  -16.74649 41.48405  1.000 22.31428  ? 7   GLY C HA3  1 
ATOM   6565 N N    . ALA C 3 8   ? -4.46012  -16.93710 44.52233  1.000 17.17013  ? 8   ALA C N    1 
ATOM   6566 C CA   . ALA C 3 8   ? -3.65043  -17.67872 45.47403  1.000 21.44126  ? 8   ALA C CA   1 
ATOM   6567 C C    . ALA C 3 8   ? -4.45825  -18.70463 46.25639  1.000 28.32343  ? 8   ALA C C    1 
ATOM   6568 O O    . ALA C 3 8   ? -3.86824  -19.48409 47.01156  1.000 31.55133  ? 8   ALA C O    1 
ATOM   6569 C CB   . ALA C 3 8   ? -2.95653  -16.71738 46.44161  1.000 24.30998  ? 8   ALA C CB   1 
ATOM   6570 H H    . ALA C 3 8   ? -4.71649  -16.16063 44.78872  1.000 20.61099  ? 8   ALA C H    1 
ATOM   6571 H HA   . ALA C 3 8   ? -2.95713  -18.15369 44.98964  1.000 25.73635  ? 8   ALA C HA   1 
ATOM   6572 H HB1  . ALA C 3 8   ? -2.42388  -17.23067 47.06908  1.000 29.17881  ? 8   ALA C HB1  1 
ATOM   6573 H HB2  . ALA C 3 8   ? -2.38563  -16.11790 45.93604  1.000 29.17881  ? 8   ALA C HB2  1 
ATOM   6574 H HB3  . ALA C 3 8   ? -3.63048  -16.20840 46.91872  1.000 29.17881  ? 8   ALA C HB3  1 
ATOM   6575 N N    . GLY C 3 9   ? -5.77676  -18.73200 46.09027  1.000 26.69976  ? 9   GLY C N    1 
ATOM   6576 C CA   . GLY C 3 9   ? -6.61528  -19.69464 46.78244  1.000 33.79736  ? 9   GLY C CA   1 
ATOM   6577 C C    . GLY C 3 9   ? -6.92747  -19.28476 48.20980  1.000 42.07649  ? 9   GLY C C    1 
ATOM   6578 O O    . GLY C 3 9   ? -6.79514  -18.11316 48.57230  1.000 43.11611  ? 9   GLY C O    1 
ATOM   6579 H H    . GLY C 3 9   ? -6.21121  -18.19672 45.57613  1.000 32.04655  ? 9   GLY C H    1 
ATOM   6580 H HA2  . GLY C 3 9   ? -7.45332  -19.79041 46.30346  1.000 40.56366  ? 9   GLY C HA2  1 
ATOM   6581 H HA3  . GLY C 3 9   ? -6.16421  -20.55310 46.80441  1.000 40.56366  ? 9   GLY C HA3  1 
HETATM 6582 O O    . HOH D 4 .   ? 6.64170   -6.65163  20.02492  1.000 22.60562  ? 301 HOH H O    1 
HETATM 6583 O O    . HOH D 4 .   ? -7.16508  -12.20370 20.57360  1.000 35.95297  ? 302 HOH H O    1 
HETATM 6584 O O    . HOH D 4 .   ? 26.80843  3.16736   -4.77701  1.000 27.81558  ? 303 HOH H O    1 
HETATM 6585 O O    . HOH D 4 .   ? 12.56287  -8.60852  9.16847   1.000 24.82255  ? 304 HOH H O    1 
HETATM 6586 O O    . HOH D 4 .   ? 18.36167  -17.50629 31.81189  1.000 28.69906  ? 305 HOH H O    1 
HETATM 6587 O O    . HOH D 4 .   ? 14.11977  -2.84597  0.54869   1.000 33.52493  ? 306 HOH H O    1 
HETATM 6588 O O    . HOH D 4 .   ? 36.32824  0.01581   2.82258   1.000 31.28558  ? 307 HOH H O    1 
HETATM 6589 O O    . HOH D 4 .   ? 8.72776   -25.41020 31.23925  1.000 21.86400  ? 308 HOH H O    1 
HETATM 6590 O O    . HOH D 4 .   ? -1.67170  -7.80771  20.04933  1.000 18.89788  ? 309 HOH H O    1 
HETATM 6591 O O    . HOH D 4 .   ? 15.47847  -21.52836 13.21342  1.000 30.95505  ? 310 HOH H O    1 
HETATM 6592 O O    . HOH D 4 .   ? -1.33877  -11.33676 13.89722  1.000 24.61984  ? 311 HOH H O    1 
HETATM 6593 O O    . HOH D 4 .   ? 13.31498  -24.26349 39.94026  1.000 32.70873  ? 312 HOH H O    1 
HETATM 6594 O O    . HOH D 4 .   ? 24.34710  7.46519   9.70423   1.000 28.03108  ? 313 HOH H O    1 
HETATM 6595 O O    . HOH D 4 .   ? 10.52887  -9.84193  -4.30873  1.000 27.04971  ? 314 HOH H O    1 
HETATM 6596 O O    . HOH D 4 .   ? 8.74771   -15.61627 12.22755  1.000 18.90568  ? 315 HOH H O    1 
HETATM 6597 O O    . HOH D 4 .   ? 3.43873   -12.65357 39.43467  1.000 14.35343  ? 316 HOH H O    1 
HETATM 6598 O O    . HOH D 4 .   ? 5.21143   -19.89238 38.25242  1.000 24.47490  ? 317 HOH H O    1 
HETATM 6599 O O    . HOH D 4 .   ? 21.20648  -18.60619 11.29869  1.000 30.21980  ? 318 HOH H O    1 
HETATM 6600 O O    . HOH D 4 .   ? 26.39824  -3.47324  14.32618  1.000 22.28982  ? 319 HOH H O    1 
HETATM 6601 O O    . HOH D 4 .   ? -5.97896  -12.43856 31.76786  1.000 23.81094  ? 320 HOH H O    1 
HETATM 6602 O O    . HOH D 4 .   ? 19.24651  -21.20600 34.78853  1.000 24.05883  ? 321 HOH H O    1 
HETATM 6603 O O    . HOH D 4 .   ? -6.20231  -11.01359 27.13612  1.000 28.98282  ? 322 HOH H O    1 
HETATM 6604 O O    . HOH D 4 .   ? -0.612    -25.572   33.921    1.000 26.19664  ? 323 HOH H O    1 
HETATM 6605 O O    . HOH D 4 .   ? 12.18400  -5.53514  39.23091  1.000 21.29728  ? 324 HOH H O    1 
HETATM 6606 O O    . HOH D 4 .   ? 5.72844   -20.28498 -0.11334  1.000 37.13217  ? 325 HOH H O    1 
HETATM 6607 O O    . HOH D 4 .   ? 5.39940   -22.07754 44.87891  1.000 29.08716  ? 326 HOH H O    1 
HETATM 6608 O O    . HOH D 4 .   ? 32.27302  -8.99295  10.56744  1.000 25.49124  ? 327 HOH H O    1 
HETATM 6609 O O    . HOH D 4 .   ? 14.67285  -3.84294  10.66929  1.000 20.27091  ? 328 HOH H O    1 
HETATM 6610 O O    . HOH D 4 .   ? 11.88417  -27.25764 30.24308  1.000 24.44303  ? 329 HOH H O    1 
HETATM 6611 O O    . HOH D 4 .   ? 34.96649  -2.75444  3.01257   1.000 27.75596  ? 330 HOH H O    1 
HETATM 6612 O O    . HOH D 4 .   ? 12.76312  -1.72192  4.24811   1.000 27.06013  ? 331 HOH H O    1 
HETATM 6613 O O    . HOH D 4 .   ? -10.79781 -20.61637 24.38410  1.000 20.72729  ? 332 HOH H O    1 
HETATM 6614 O O    . HOH D 4 .   ? -8.28769  -20.85583 22.17920  1.000 27.29669  ? 333 HOH H O    1 
HETATM 6615 O O    . HOH D 4 .   ? 1.12943   -15.81209 41.74414  1.000 16.60851  ? 334 HOH H O    1 
HETATM 6616 O O    . HOH D 4 .   ? 18.87325  1.14928   13.21514  1.000 25.17769  ? 335 HOH H O    1 
HETATM 6617 O O    . HOH D 4 .   ? 30.32429  5.43949   11.72202  1.000 31.71115  ? 336 HOH H O    1 
HETATM 6618 O O    . HOH D 4 .   ? 11.38102  -4.97897  10.35970  1.000 29.81838  ? 337 HOH H O    1 
HETATM 6619 O O    . HOH D 4 .   ? 0.47666   -14.54868 8.88841   1.000 30.21745  ? 338 HOH H O    1 
HETATM 6620 O O    . HOH D 4 .   ? 14.60862  -20.79632 27.18572  1.000 28.05387  ? 339 HOH H O    1 
HETATM 6621 O O    . HOH D 4 .   ? -2.08464  -27.80441 16.44046  1.000 26.26259  ? 340 HOH H O    1 
HETATM 6622 O O    . HOH D 4 .   ? 26.59418  -1.31032  -4.80952  1.000 30.34713  ? 341 HOH H O    1 
HETATM 6623 O O    . HOH D 4 .   ? 16.54930  -13.84672 12.44448  1.000 19.80189  ? 342 HOH H O    1 
HETATM 6624 O O    . HOH D 4 .   ? 16.32401  -12.10376 27.95158  1.000 32.48063  ? 343 HOH H O    1 
HETATM 6625 O O    . HOH D 4 .   ? -7.888    -22.510   15.671    1.000 15.93030  ? 344 HOH H O    1 
HETATM 6626 O O    . HOH D 4 .   ? 30.43822  2.37847   16.45397  1.000 33.18358  ? 345 HOH H O    1 
HETATM 6627 O O    . HOH D 4 .   ? 4.54853   -13.79281 41.91922  1.000 19.11513  ? 346 HOH H O    1 
HETATM 6628 O O    . HOH D 4 .   ? 7.77119   -17.99399 0.52877   1.000 32.58171  ? 347 HOH H O    1 
HETATM 6629 O O    . HOH D 4 .   ? -3.22841  -25.63073 32.90461  1.000 23.85372  ? 348 HOH H O    1 
HETATM 6630 O O    . HOH D 4 .   ? -6.22169  -15.06831 18.15561  1.000 35.33311  ? 349 HOH H O    1 
HETATM 6631 O O    . HOH D 4 .   ? 14.44865  -7.85575  36.87278  1.000 25.19718  ? 350 HOH H O    1 
HETATM 6632 O O    . HOH D 4 .   ? -7.48638  -21.16006 33.14684  1.000 23.97779  ? 351 HOH H O    1 
HETATM 6633 O O    . HOH D 4 .   ? 14.34977  -8.96506  28.14111  1.000 33.09913  ? 352 HOH H O    1 
HETATM 6634 O O    . HOH D 4 .   ? 10.98331  -21.00090 11.08509  1.000 29.54955  ? 353 HOH H O    1 
HETATM 6635 O O    . HOH D 4 .   ? 2.84775   -11.66912 35.68257  1.000 11.12505  ? 354 HOH H O    1 
HETATM 6636 O O    . HOH D 4 .   ? -9.01047  -27.66991 25.27978  1.000 25.52545  ? 355 HOH H O    1 
HETATM 6637 O O    . HOH D 4 .   ? -10.19612 -24.11798 19.91892  1.000 31.69518  ? 356 HOH H O    1 
HETATM 6638 O O    . HOH D 4 .   ? 18.92387  -5.90985  13.17828  1.000 24.57001  ? 357 HOH H O    1 
HETATM 6639 O O    . HOH D 4 .   ? 3.00495   -25.72777 28.45545  1.000 20.69531  ? 358 HOH H O    1 
HETATM 6640 O O    . HOH D 4 .   ? -10.48422 -13.87049 30.02462  1.000 33.75163  ? 359 HOH H O    1 
HETATM 6641 O O    . HOH D 4 .   ? 12.01367  -13.27515 16.90081  1.000 30.30608  ? 360 HOH H O    1 
HETATM 6642 O O    . HOH D 4 .   ? 31.18662  -5.17198  -2.19904  1.000 28.18227  ? 361 HOH H O    1 
HETATM 6643 O O    . HOH D 4 .   ? 16.77284  -19.41101 42.89242  1.000 30.43371  ? 362 HOH H O    1 
HETATM 6644 O O    . HOH D 4 .   ? 34.26425  -1.40759  13.16938  1.000 32.21346  ? 363 HOH H O    1 
HETATM 6645 O O    . HOH D 4 .   ? 17.493    -25.335   31.858    1.000 25.54617  ? 364 HOH H O    1 
HETATM 6646 O O    . HOH D 4 .   ? 15.41189  -11.08295 31.05371  1.000 26.28540  ? 365 HOH H O    1 
HETATM 6647 O O    . HOH D 4 .   ? -5.09089  -8.59181  27.53682  1.000 21.16299  ? 366 HOH H O    1 
HETATM 6648 O O    . HOH D 4 .   ? -5.94655  -26.11582 26.40780  1.000 22.26775  ? 367 HOH H O    1 
HETATM 6649 O O    . HOH D 4 .   ? 13.78379  -17.44074 43.89468  1.000 24.99423  ? 368 HOH H O    1 
HETATM 6650 O O    . HOH D 4 .   ? 12.98536  -7.38688  32.06529  1.000 18.35993  ? 369 HOH H O    1 
HETATM 6651 O O    . HOH D 4 .   ? 23.06083  -10.29754 12.64580  1.000 22.29121  ? 370 HOH H O    1 
HETATM 6652 O O    . HOH D 4 .   ? 6.80486   -12.64957 9.22474   1.000 22.14658  ? 371 HOH H O    1 
HETATM 6653 O O    . HOH D 4 .   ? 3.28177   -27.61424 14.24562  1.000 29.80777  ? 372 HOH H O    1 
HETATM 6654 O O    . HOH D 4 .   ? 12.81533  -3.83779  -1.84649  1.000 34.89385  ? 373 HOH H O    1 
HETATM 6655 O O    . HOH D 4 .   ? 3.25455   -27.22141 21.54241  1.000 27.13823  ? 374 HOH H O    1 
HETATM 6656 O O    . HOH D 4 .   ? -0.11547  -18.35262 44.20484  1.000 22.45202  ? 375 HOH H O    1 
HETATM 6657 O O    . HOH D 4 .   ? 3.25806   -26.78104 35.63726  1.000 23.84944  ? 376 HOH H O    1 
HETATM 6658 O O    . HOH D 4 .   ? 7.47024   -23.12517 18.35251  1.000 27.51999  ? 377 HOH H O    1 
HETATM 6659 O O    . HOH D 4 .   ? 8.55025   -9.11231  44.05995  1.000 32.31033  ? 378 HOH H O    1 
HETATM 6660 O O    . HOH D 4 .   ? 7.00905   -4.45721  -4.16796  1.000 36.23945  ? 379 HOH H O    1 
HETATM 6661 O O    . HOH D 4 .   ? 6.02865   -11.14223 43.84010  1.000 23.81627  ? 380 HOH H O    1 
HETATM 6662 O O    . HOH D 4 .   ? 32.81799  -11.56518 9.17740   1.000 32.56457  ? 381 HOH H O    1 
HETATM 6663 O O    . HOH E 4 .   ? -10.249   9.118     31.680    1.000 30.20095  ? 301 HOH L O    1 
HETATM 6664 O O    . HOH E 4 .   ? -4.94890  11.90621  34.76185  1.000 19.84145  ? 302 HOH L O    1 
HETATM 6665 O O    . HOH E 4 .   ? -13.462   -16.110   41.585    1.000 28.84829  ? 303 HOH L O    1 
HETATM 6666 O O    . HOH E 4 .   ? 5.24562   3.45108   -5.12317  1.000 29.98994  ? 304 HOH L O    1 
HETATM 6667 O O    . HOH E 4 .   ? 12.25521  19.45254  21.55763  1.000 25.03890  ? 305 HOH L O    1 
HETATM 6668 O O    . HOH E 4 .   ? 21.61025  -4.18159  -5.70009  1.000 23.42325  ? 306 HOH L O    1 
HETATM 6669 O O    . HOH E 4 .   ? 3.02520   4.38683   -12.82838 1.000 33.33050  ? 307 HOH L O    1 
HETATM 6670 O O    . HOH E 4 .   ? 7.41331   10.45585  -0.60138  1.000 33.06624  ? 308 HOH L O    1 
HETATM 6671 O O    . HOH E 4 .   ? 23.54230  9.37122   11.43435  1.000 34.57163  ? 309 HOH L O    1 
HETATM 6672 O O    . HOH E 4 .   ? -7.36520  -9.24405  30.20085  1.000 30.87540  ? 310 HOH L O    1 
HETATM 6673 O O    . HOH E 4 .   ? -8.57805  7.52663   29.87157  1.000 30.09367  ? 311 HOH L O    1 
HETATM 6674 O O    . HOH E 4 .   ? 10.46877  -0.89867  -4.60588  1.000 22.67033  ? 312 HOH L O    1 
HETATM 6675 O O    . HOH E 4 .   ? 9.68685   22.45568  26.29208  1.000 37.00270  ? 313 HOH L O    1 
HETATM 6676 O O    . HOH E 4 .   ? 13.46482  -4.02715  26.87897  1.000 29.68730  ? 314 HOH L O    1 
HETATM 6677 O O    . HOH E 4 .   ? -8.94678  -16.07086 34.94460  1.000 28.33413  ? 315 HOH L O    1 
HETATM 6678 O O    . HOH E 4 .   ? 13.62789  -3.85342  -4.57186  1.000 24.60996  ? 316 HOH L O    1 
HETATM 6679 O O    . HOH E 4 .   ? 8.75855   20.61372  32.55166  1.000 31.81321  ? 317 HOH L O    1 
HETATM 6680 O O    . HOH E 4 .   ? 7.86045   10.11826  2.95393   1.000 29.70856  ? 318 HOH L O    1 
HETATM 6681 O O    . HOH E 4 .   ? 16.02964  11.40873  -14.75898 1.000 25.93135  ? 319 HOH L O    1 
HETATM 6682 O O    . HOH E 4 .   ? 0.08668   15.17797  35.77583  1.000 25.47614  ? 320 HOH L O    1 
HETATM 6683 O O    . HOH E 4 .   ? 9.45092   21.82880  14.15642  1.000 26.17946  ? 321 HOH L O    1 
HETATM 6684 O O    . HOH E 4 .   ? 13.27200  14.80044  38.41575  1.000 27.53631  ? 322 HOH L O    1 
HETATM 6685 O O    . HOH E 4 .   ? 10.61587  -2.12966  -2.18508  1.000 29.08735  ? 323 HOH L O    1 
HETATM 6686 O O    . HOH E 4 .   ? 10.82577  16.70690  6.63785   1.000 28.89528  ? 324 HOH L O    1 
HETATM 6687 O O    . HOH E 4 .   ? 9.38879   7.45873   -2.45565  1.000 29.57077  ? 325 HOH L O    1 
HETATM 6688 O O    . HOH E 4 .   ? -8.57315  7.55882   24.48545  1.000 27.09436  ? 326 HOH L O    1 
HETATM 6689 O O    . HOH E 4 .   ? -5.49548  -14.72332 33.35017  1.000 22.76388  ? 327 HOH L O    1 
HETATM 6690 O O    . HOH E 4 .   ? 20.84726  -0.38829  -4.78491  1.000 21.40599  ? 328 HOH L O    1 
HETATM 6691 O O    . HOH E 4 .   ? 8.82765   13.57530  38.94664  1.000 30.13359  ? 329 HOH L O    1 
HETATM 6692 O O    . HOH E 4 .   ? 13.85094  11.39804  20.33722  1.000 18.00530  ? 330 HOH L O    1 
HETATM 6693 O O    . HOH E 4 .   ? 16.47941  7.45475   13.51924  1.000 30.76867  ? 331 HOH L O    1 
HETATM 6694 O O    . HOH E 4 .   ? 14.04855  15.89732  32.25266  1.000 32.64637  ? 332 HOH L O    1 
HETATM 6695 O O    . HOH E 4 .   ? 13.18721  6.90442   28.89792  1.000 17.20066  ? 333 HOH L O    1 
HETATM 6696 O O    . HOH E 4 .   ? 5.02240   7.78570   -14.17211 1.000 32.89104  ? 334 HOH L O    1 
HETATM 6697 O O    . HOH E 4 .   ? 15.06463  -0.02690  3.43186   1.000 23.40701  ? 335 HOH L O    1 
HETATM 6698 O O    . HOH E 4 .   ? -11.146   -18.824   37.830    1.000 18.25905  ? 336 HOH L O    1 
HETATM 6699 O O    . HOH E 4 .   ? 8.75852   8.67034   17.85860  1.000 23.55971  ? 337 HOH L O    1 
HETATM 6700 O O    . HOH E 4 .   ? 4.88236   10.27258  -8.21134  1.000 28.70301  ? 338 HOH L O    1 
HETATM 6701 O O    . HOH E 4 .   ? 11.80215  -5.21679  30.78408  1.000 27.96561  ? 339 HOH L O    1 
HETATM 6702 O O    . HOH E 4 .   ? 25.63293  7.29088   -2.52165  1.000 32.75367  ? 340 HOH L O    1 
HETATM 6703 O O    . HOH E 4 .   ? 15.63169  -0.76025  0.87428   1.000 27.26265  ? 341 HOH L O    1 
HETATM 6704 O O    . HOH E 4 .   ? 6.02107   3.11727   0.71185   1.000 32.21261  ? 342 HOH L O    1 
HETATM 6705 O O    . HOH E 4 .   ? -2.79227  -3.21375  24.52313  1.000 18.93487  ? 343 HOH L O    1 
HETATM 6706 O O    . HOH E 4 .   ? -5.27371  9.33589   38.55290  1.000 22.02894  ? 344 HOH L O    1 
HETATM 6707 O O    . HOH E 4 .   ? -0.34653  5.21349   38.33314  1.000 14.04992  ? 345 HOH L O    1 
HETATM 6708 O O    . HOH E 4 .   ? 16.056    19.782    -6.893    1.000 21.12615  ? 346 HOH L O    1 
HETATM 6709 O O    . HOH E 4 .   ? 7.92199   5.65125   -7.62144  1.000 25.36989  ? 347 HOH L O    1 
HETATM 6710 O O    . HOH E 4 .   ? -7.88593  -3.11596  28.07416  1.000 27.48964  ? 348 HOH L O    1 
HETATM 6711 O O    . HOH E 4 .   ? 10.65284  15.66888  38.49894  1.000 35.95698  ? 349 HOH L O    1 
HETATM 6712 O O    . HOH E 4 .   ? 2.83691   2.57716   45.86917  1.000 34.79897  ? 350 HOH L O    1 
HETATM 6713 O O    . HOH E 4 .   ? 8.37668   8.58391   -7.62871  1.000 20.04525  ? 351 HOH L O    1 
HETATM 6714 O O    . HOH E 4 .   ? -11.80072 1.70216   30.53715  1.000 31.66009  ? 352 HOH L O    1 
HETATM 6715 O O    . HOH E 4 .   ? -0.35285  -0.00459  21.13381  1.000 30.76505  ? 353 HOH L O    1 
HETATM 6716 O O    . HOH E 4 .   ? 6.58722   13.40485  37.28198  1.000 19.88897  ? 354 HOH L O    1 
HETATM 6717 O O    . HOH E 4 .   ? 5.61688   -0.48794  -5.50299  1.000 34.18054  ? 355 HOH L O    1 
HETATM 6718 O O    . HOH E 4 .   ? 13.49744  -7.12412  23.81583  1.000 28.84781  ? 356 HOH L O    1 
HETATM 6719 O O    . HOH E 4 .   ? -11.08692 6.96711   41.05133  1.000 29.41529  ? 357 HOH L O    1 
HETATM 6720 O O    . HOH E 4 .   ? 9.98375   15.31491  -4.47479  1.000 29.53074  ? 358 HOH L O    1 
HETATM 6721 O O    . HOH E 4 .   ? 1.15886   11.07233  37.98976  1.000 20.21068  ? 359 HOH L O    1 
HETATM 6722 O O    . HOH E 4 .   ? 21.04367  15.58254  7.93645   1.000 26.50291  ? 360 HOH L O    1 
HETATM 6723 O O    . HOH E 4 .   ? 11.28164  -3.73172  33.35923  1.000 26.30534  ? 361 HOH L O    1 
HETATM 6724 O O    . HOH E 4 .   ? 7.18882   14.39738  16.25234  1.000 34.37367  ? 362 HOH L O    1 
HETATM 6725 O O    . HOH E 4 .   ? 12.61635  1.56084   1.06304   1.000 25.08347  ? 363 HOH L O    1 
HETATM 6726 O O    . HOH E 4 .   ? 5.54436   8.05864   41.47767  1.000 18.69655  ? 364 HOH L O    1 
HETATM 6727 O O    . HOH E 4 .   ? 9.65561   21.84637  19.24328  1.000 34.49145  ? 365 HOH L O    1 
HETATM 6728 O O    . HOH E 4 .   ? 1.61350   9.70407   43.64574  1.000 26.14896  ? 366 HOH L O    1 
HETATM 6729 O O    . HOH E 4 .   ? -10.74947 8.97781   34.11386  1.000 34.48263  ? 367 HOH L O    1 
HETATM 6730 O O    . HOH E 4 .   ? 18.63504  21.86189  8.38848   1.000 29.49917  ? 368 HOH L O    1 
HETATM 6731 O O    . HOH E 4 .   ? -5.15691  10.34315  20.78195  1.000 28.01597  ? 369 HOH L O    1 
HETATM 6732 O O    . HOH E 4 .   ? -0.60788  -6.14176  46.18266  1.000 32.33562  ? 370 HOH L O    1 
HETATM 6733 O O    . HOH E 4 .   ? -9.51436  -6.82241  40.87147  1.000 23.05890  ? 371 HOH L O    1 
HETATM 6734 O O    . HOH E 4 .   ? 17.95802  9.42927   12.53670  1.000 31.10957  ? 372 HOH L O    1 
HETATM 6735 O O    . HOH E 4 .   ? 7.51716   14.24975  12.59009  1.000 28.08025  ? 373 HOH L O    1 
HETATM 6736 O O    . HOH E 4 .   ? 11.44602  -1.09124  25.43716  1.000 18.78495  ? 374 HOH L O    1 
HETATM 6737 O O    . HOH E 4 .   ? 20.804    15.775    -9.711    1.000 22.64959  ? 375 HOH L O    1 
HETATM 6738 O O    . HOH E 4 .   ? 24.84762  9.85777   -3.30433  1.000 22.03095  ? 376 HOH L O    1 
HETATM 6739 O O    . HOH E 4 .   ? -5.98124  -6.31397  27.92592  1.000 19.44953  ? 377 HOH L O    1 
HETATM 6740 O O    . HOH E 4 .   ? 24.59544  11.85673  7.02491   1.000 33.46070  ? 378 HOH L O    1 
HETATM 6741 O O    . HOH E 4 .   ? 11.84724  1.07690   26.96459  1.000 25.94139  ? 379 HOH L O    1 
HETATM 6742 O O    . HOH E 4 .   ? 25.66610  2.43953   -12.46494 1.000 36.86009  ? 380 HOH L O    1 
HETATM 6743 O O    . HOH E 4 .   ? -8.86548  -7.04500  45.63709  1.000 26.21635  ? 381 HOH L O    1 
HETATM 6744 O O    . HOH E 4 .   ? 0.06496   16.21939  21.40886  1.000 19.92868  ? 382 HOH L O    1 
HETATM 6745 O O    . HOH E 4 .   ? 3.28068   19.32131  25.02655  1.000 25.23106  ? 383 HOH L O    1 
HETATM 6746 O O    . HOH E 4 .   ? 7.37624   19.43202  3.24929   1.000 30.61550  ? 384 HOH L O    1 
HETATM 6747 O O    . HOH E 4 .   ? 5.44250   5.02329   -13.48034 1.000 36.18907  ? 385 HOH L O    1 
HETATM 6748 O O    . HOH E 4 .   ? 14.90601  18.85968  0.90653   1.000 32.93405  ? 386 HOH L O    1 
HETATM 6749 O O    . HOH E 4 .   ? -1.76049  4.03647   20.29658  1.000 34.51502  ? 387 HOH L O    1 
HETATM 6750 O O    . HOH E 4 .   ? -10.33577 -7.43677  43.66741  1.000 31.55125  ? 388 HOH L O    1 
HETATM 6751 O O    . HOH E 4 .   ? 16.82194  -8.88812  -6.51037  1.000 29.91610  ? 389 HOH L O    1 
HETATM 6752 O O    . HOH E 4 .   ? 13.91278  -4.47279  29.26278  1.000 34.23222  ? 390 HOH L O    1 
HETATM 6753 O O    . HOH E 4 .   ? 27.01715  9.00875   -12.19175 1.000 29.63289  ? 391 HOH L O    1 
HETATM 6754 O O    . HOH E 4 .   ? 26.74902  5.68086   -4.23611  1.000 36.66021  ? 392 HOH L O    1 
HETATM 6755 O O    . HOH E 4 .   ? 17.32238  -3.66408  -22.11954 1.000 36.63993  ? 393 HOH L O    1 
HETATM 6756 O O    . HOH E 4 .   ? 14.93464  21.04817  18.90553  1.000 30.30957  ? 394 HOH L O    1 
HETATM 6757 O O    . HOH E 4 .   ? 15.02363  12.42775  35.28607  1.000 21.22437  ? 395 HOH L O    1 
HETATM 6758 O O    . HOH E 4 .   ? 13.32263  -6.76886  17.86153  1.000 33.14672  ? 396 HOH L O    1 
HETATM 6759 O O    . HOH E 4 .   ? 7.81165   -1.38862  -5.60058  1.000 30.88534  ? 397 HOH L O    1 
HETATM 6760 O O    . HOH E 4 .   ? 14.42448  -6.95227  26.05884  1.000 32.49940  ? 398 HOH L O    1 
HETATM 6761 O O    . HOH E 4 .   ? 28.58456  -2.75971  -5.76915  1.000 25.70975  ? 399 HOH L O    1 
HETATM 6762 O O    . HOH E 4 .   ? 24.040    -15.509   -10.877   1.000 36.44577  ? 400 HOH L O    1 
HETATM 6763 O O    . HOH E 4 .   ? -8.14265  -11.83377 30.00648  1.000 27.25513  ? 401 HOH L O    1 
HETATM 6764 O O    . HOH F 4 .   ? -2.51432  -20.37447 43.08869  1.000 27.31636  ? 101 HOH C O    1 
HETATM 6765 O O    . HOH F 4 .   ? 1.91419   -7.91351  43.72772  1.000 24.28535  ? 102 HOH C O    1 
HETATM 6766 O O    . HOH F 4 .   ? -5.21056  -14.50434 45.70774  1.000 17.69129  ? 103 HOH C O    1 
HETATM 6767 O O    . HOH F 4 .   ? -1.18640  -15.82169 43.18714  1.000 20.38311  ? 104 HOH C O    1 
HETATM 6768 O O    . HOH F 4 .   ? -0.17549  -14.17467 45.52424  1.000 28.79824  ? 105 HOH C O    1 
# 
