data_9UET
# 
_entry.id   9UET 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9UET         pdb_00009uet 10.2210/pdb9uet/pdb 
WWPDB D_1300058371 ?            ?                   
EMDB  EMD-64091    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-06-18 ? 
2 'EM metadata'     1 0 2025-06-18 ? 
3 'Half map'        1 0 2025-06-18 1 
4 'Half map'        1 0 2025-06-18 2 
5 Image             1 0 2025-06-18 ? 
6 'Primary map'     1 0 2025-06-18 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9UET 
_pdbx_database_status.recvd_initial_deposition_date   2025-04-09 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human choline-phosphotransferase 1' 
_pdbx_database_related.db_id          EMD-64091 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              hongwuqian@ustc.edu.cn 
_pdbx_contact_author.name_first         Hongwu 
_pdbx_contact_author.name_last          Qian 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9940-8003 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'He, Y.L.'   1 0009-0005-4798-2923 
'Qian, H.W.' 2 0000-0001-9940-8003 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of human choline-phosphotransferase 1' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'He, Y.L.'   1 0009-0005-4798-2923 
primary 'Qian, H.W.' 2 0000-0001-9940-8003 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Cholinephosphotransferase 1'                                                                    45131.707 2 
2.7.8.2 ? ? ? 
2 non-polymer syn '(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate' 760.076   2 ? ? 
? ? 
3 non-polymer syn 'MAGNESIUM ION'                                                                                  24.305    4 ? ? 
? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'human choline-phosphotransferase 1, hCPT1,AAPT1-like protein,Diacylglycerol cholinephosphotransferase 1' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLV
LISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWF
FFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC
SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKS
ELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKS
HQNNMD
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLV
LISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWF
FFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC
SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKS
ELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKS
HQNNMD
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 '(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate' POV 
3 'MAGNESIUM ION'                                                                                  MG  
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   ALA n 
1 4   GLY n 
1 5   ALA n 
1 6   GLY n 
1 7   ALA n 
1 8   GLY n 
1 9   SER n 
1 10  ALA n 
1 11  PRO n 
1 12  ARG n 
1 13  TRP n 
1 14  LEU n 
1 15  ARG n 
1 16  ALA n 
1 17  LEU n 
1 18  SER n 
1 19  GLU n 
1 20  PRO n 
1 21  LEU n 
1 22  SER n 
1 23  ALA n 
1 24  ALA n 
1 25  GLN n 
1 26  LEU n 
1 27  ARG n 
1 28  ARG n 
1 29  LEU n 
1 30  GLU n 
1 31  GLU n 
1 32  HIS n 
1 33  ARG n 
1 34  TYR n 
1 35  SER n 
1 36  ALA n 
1 37  ALA n 
1 38  GLY n 
1 39  VAL n 
1 40  SER n 
1 41  LEU n 
1 42  LEU n 
1 43  GLU n 
1 44  PRO n 
1 45  PRO n 
1 46  LEU n 
1 47  GLN n 
1 48  LEU n 
1 49  TYR n 
1 50  TRP n 
1 51  THR n 
1 52  TRP n 
1 53  LEU n 
1 54  LEU n 
1 55  GLN n 
1 56  TRP n 
1 57  ILE n 
1 58  PRO n 
1 59  LEU n 
1 60  TRP n 
1 61  MET n 
1 62  ALA n 
1 63  PRO n 
1 64  ASN n 
1 65  SER n 
1 66  ILE n 
1 67  THR n 
1 68  LEU n 
1 69  LEU n 
1 70  GLY n 
1 71  LEU n 
1 72  ALA n 
1 73  VAL n 
1 74  ASN n 
1 75  VAL n 
1 76  VAL n 
1 77  THR n 
1 78  THR n 
1 79  LEU n 
1 80  VAL n 
1 81  LEU n 
1 82  ILE n 
1 83  SER n 
1 84  TYR n 
1 85  CYS n 
1 86  PRO n 
1 87  THR n 
1 88  ALA n 
1 89  THR n 
1 90  GLU n 
1 91  GLU n 
1 92  ALA n 
1 93  PRO n 
1 94  TYR n 
1 95  TRP n 
1 96  THR n 
1 97  TYR n 
1 98  LEU n 
1 99  LEU n 
1 100 CYS n 
1 101 ALA n 
1 102 LEU n 
1 103 GLY n 
1 104 LEU n 
1 105 PHE n 
1 106 ILE n 
1 107 TYR n 
1 108 GLN n 
1 109 SER n 
1 110 LEU n 
1 111 ASP n 
1 112 ALA n 
1 113 ILE n 
1 114 ASP n 
1 115 GLY n 
1 116 LYS n 
1 117 GLN n 
1 118 ALA n 
1 119 ARG n 
1 120 ARG n 
1 121 THR n 
1 122 ASN n 
1 123 SER n 
1 124 CYS n 
1 125 SER n 
1 126 PRO n 
1 127 LEU n 
1 128 GLY n 
1 129 GLU n 
1 130 LEU n 
1 131 PHE n 
1 132 ASP n 
1 133 HIS n 
1 134 GLY n 
1 135 CYS n 
1 136 ASP n 
1 137 SER n 
1 138 LEU n 
1 139 SER n 
1 140 THR n 
1 141 VAL n 
1 142 PHE n 
1 143 MET n 
1 144 ALA n 
1 145 VAL n 
1 146 GLY n 
1 147 ALA n 
1 148 SER n 
1 149 ILE n 
1 150 ALA n 
1 151 ALA n 
1 152 ARG n 
1 153 LEU n 
1 154 GLY n 
1 155 THR n 
1 156 TYR n 
1 157 PRO n 
1 158 ASP n 
1 159 TRP n 
1 160 PHE n 
1 161 PHE n 
1 162 PHE n 
1 163 CYS n 
1 164 SER n 
1 165 PHE n 
1 166 ILE n 
1 167 GLY n 
1 168 MET n 
1 169 PHE n 
1 170 VAL n 
1 171 PHE n 
1 172 TYR n 
1 173 CYS n 
1 174 ALA n 
1 175 HIS n 
1 176 TRP n 
1 177 GLN n 
1 178 THR n 
1 179 TYR n 
1 180 VAL n 
1 181 SER n 
1 182 GLY n 
1 183 MET n 
1 184 LEU n 
1 185 ARG n 
1 186 PHE n 
1 187 GLY n 
1 188 LYS n 
1 189 VAL n 
1 190 ASP n 
1 191 VAL n 
1 192 THR n 
1 193 GLU n 
1 194 ILE n 
1 195 GLN n 
1 196 ILE n 
1 197 ALA n 
1 198 LEU n 
1 199 VAL n 
1 200 ILE n 
1 201 VAL n 
1 202 PHE n 
1 203 VAL n 
1 204 LEU n 
1 205 SER n 
1 206 ALA n 
1 207 PHE n 
1 208 GLY n 
1 209 GLY n 
1 210 ALA n 
1 211 THR n 
1 212 MET n 
1 213 TRP n 
1 214 ASP n 
1 215 TYR n 
1 216 THR n 
1 217 ILE n 
1 218 PRO n 
1 219 ILE n 
1 220 LEU n 
1 221 GLU n 
1 222 ILE n 
1 223 LYS n 
1 224 LEU n 
1 225 LYS n 
1 226 ILE n 
1 227 LEU n 
1 228 PRO n 
1 229 VAL n 
1 230 LEU n 
1 231 GLY n 
1 232 PHE n 
1 233 LEU n 
1 234 GLY n 
1 235 GLY n 
1 236 VAL n 
1 237 ILE n 
1 238 PHE n 
1 239 SER n 
1 240 CYS n 
1 241 SER n 
1 242 ASN n 
1 243 TYR n 
1 244 PHE n 
1 245 HIS n 
1 246 VAL n 
1 247 ILE n 
1 248 LEU n 
1 249 HIS n 
1 250 GLY n 
1 251 GLY n 
1 252 VAL n 
1 253 GLY n 
1 254 LYS n 
1 255 ASN n 
1 256 GLY n 
1 257 SER n 
1 258 THR n 
1 259 ILE n 
1 260 ALA n 
1 261 GLY n 
1 262 THR n 
1 263 SER n 
1 264 VAL n 
1 265 LEU n 
1 266 SER n 
1 267 PRO n 
1 268 GLY n 
1 269 LEU n 
1 270 HIS n 
1 271 ILE n 
1 272 GLY n 
1 273 LEU n 
1 274 ILE n 
1 275 ILE n 
1 276 ILE n 
1 277 LEU n 
1 278 ALA n 
1 279 ILE n 
1 280 MET n 
1 281 ILE n 
1 282 TYR n 
1 283 LYS n 
1 284 LYS n 
1 285 SER n 
1 286 ALA n 
1 287 THR n 
1 288 ASP n 
1 289 VAL n 
1 290 PHE n 
1 291 GLU n 
1 292 LYS n 
1 293 HIS n 
1 294 PRO n 
1 295 CYS n 
1 296 LEU n 
1 297 TYR n 
1 298 ILE n 
1 299 LEU n 
1 300 MET n 
1 301 PHE n 
1 302 GLY n 
1 303 CYS n 
1 304 VAL n 
1 305 PHE n 
1 306 ALA n 
1 307 LYS n 
1 308 VAL n 
1 309 SER n 
1 310 GLN n 
1 311 LYS n 
1 312 LEU n 
1 313 VAL n 
1 314 VAL n 
1 315 ALA n 
1 316 HIS n 
1 317 MET n 
1 318 THR n 
1 319 LYS n 
1 320 SER n 
1 321 GLU n 
1 322 LEU n 
1 323 TYR n 
1 324 LEU n 
1 325 GLN n 
1 326 ASP n 
1 327 THR n 
1 328 VAL n 
1 329 PHE n 
1 330 LEU n 
1 331 GLY n 
1 332 PRO n 
1 333 GLY n 
1 334 LEU n 
1 335 LEU n 
1 336 PHE n 
1 337 LEU n 
1 338 ASP n 
1 339 GLN n 
1 340 TYR n 
1 341 PHE n 
1 342 ASN n 
1 343 ASN n 
1 344 PHE n 
1 345 ILE n 
1 346 ASP n 
1 347 GLU n 
1 348 TYR n 
1 349 VAL n 
1 350 VAL n 
1 351 LEU n 
1 352 TRP n 
1 353 MET n 
1 354 ALA n 
1 355 MET n 
1 356 VAL n 
1 357 ILE n 
1 358 SER n 
1 359 SER n 
1 360 PHE n 
1 361 ASP n 
1 362 MET n 
1 363 VAL n 
1 364 ILE n 
1 365 TYR n 
1 366 PHE n 
1 367 SER n 
1 368 ALA n 
1 369 LEU n 
1 370 CYS n 
1 371 LEU n 
1 372 GLN n 
1 373 ILE n 
1 374 SER n 
1 375 ARG n 
1 376 HIS n 
1 377 LEU n 
1 378 HIS n 
1 379 LEU n 
1 380 ASN n 
1 381 ILE n 
1 382 PHE n 
1 383 LYS n 
1 384 THR n 
1 385 ALA n 
1 386 CYS n 
1 387 HIS n 
1 388 GLN n 
1 389 ALA n 
1 390 PRO n 
1 391 GLU n 
1 392 GLN n 
1 393 VAL n 
1 394 GLN n 
1 395 VAL n 
1 396 LEU n 
1 397 SER n 
1 398 SER n 
1 399 LYS n 
1 400 SER n 
1 401 HIS n 
1 402 GLN n 
1 403 ASN n 
1 404 ASN n 
1 405 MET n 
1 406 ASP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   406 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'CHPT1, CPT1, MSTP022' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            'HEK 293F' 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                                                                          ?    
'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                                                                         ?    
'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                                                                                       ?    
'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                                                                                  ?    
'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                                                                         ?    
'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE                                                                                        ?    
'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                                                                                  ?    
'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                                                                          ?    
'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                                                                                        ?    
'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                                                                                       ?    
'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                                                                          ?    
'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                                                                           ?    
'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                                                                                       ?    
'C5 H11 N O2 S'  149.211 
MG  non-polymer         . 'MAGNESIUM ION'                                                                                  ?    
'Mg 2'           24.305  
PHE 'L-peptide linking' y PHENYLALANINE                                                                                    ?    
'C9 H11 N O2'    165.189 
POV non-polymer         . '(2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate' POPC 
'C42 H82 N O8 P' 760.076 
PRO 'L-peptide linking' y PROLINE                                                                                          ?    
'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                                                                           ?    
'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                                                                                        ?    
'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                                                                                       ?    
'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                                                                         ?    
'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                                                                           ?    
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   ALA 3   3   ?   ?   ?   A . n 
A 1 4   GLY 4   4   ?   ?   ?   A . n 
A 1 5   ALA 5   5   ?   ?   ?   A . n 
A 1 6   GLY 6   6   ?   ?   ?   A . n 
A 1 7   ALA 7   7   ?   ?   ?   A . n 
A 1 8   GLY 8   8   ?   ?   ?   A . n 
A 1 9   SER 9   9   ?   ?   ?   A . n 
A 1 10  ALA 10  10  ?   ?   ?   A . n 
A 1 11  PRO 11  11  ?   ?   ?   A . n 
A 1 12  ARG 12  12  ?   ?   ?   A . n 
A 1 13  TRP 13  13  ?   ?   ?   A . n 
A 1 14  LEU 14  14  ?   ?   ?   A . n 
A 1 15  ARG 15  15  ?   ?   ?   A . n 
A 1 16  ALA 16  16  16  ALA ALA A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  SER 18  18  18  SER SER A . n 
A 1 19  GLU 19  19  19  GLU GLU A . n 
A 1 20  PRO 20  20  20  PRO PRO A . n 
A 1 21  LEU 21  21  21  LEU LEU A . n 
A 1 22  SER 22  22  22  SER SER A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  GLN 25  25  25  GLN GLN A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  ARG 27  27  27  ARG ARG A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  LEU 29  29  29  LEU LEU A . n 
A 1 30  GLU 30  30  30  GLU GLU A . n 
A 1 31  GLU 31  31  31  GLU GLU A . n 
A 1 32  HIS 32  32  32  HIS HIS A . n 
A 1 33  ARG 33  33  33  ARG ARG A . n 
A 1 34  TYR 34  34  34  TYR TYR A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  ALA 36  36  36  ALA ALA A . n 
A 1 37  ALA 37  37  37  ALA ALA A . n 
A 1 38  GLY 38  38  38  GLY GLY A . n 
A 1 39  VAL 39  39  39  VAL VAL A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  LEU 41  41  41  LEU LEU A . n 
A 1 42  LEU 42  42  42  LEU LEU A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  PRO 44  44  44  PRO PRO A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  GLN 47  47  47  GLN GLN A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  TYR 49  49  49  TYR TYR A . n 
A 1 50  TRP 50  50  50  TRP TRP A . n 
A 1 51  THR 51  51  51  THR THR A . n 
A 1 52  TRP 52  52  52  TRP TRP A . n 
A 1 53  LEU 53  53  53  LEU LEU A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  GLN 55  55  55  GLN GLN A . n 
A 1 56  TRP 56  56  56  TRP TRP A . n 
A 1 57  ILE 57  57  57  ILE ILE A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  TRP 60  60  60  TRP TRP A . n 
A 1 61  MET 61  61  61  MET MET A . n 
A 1 62  ALA 62  62  62  ALA ALA A . n 
A 1 63  PRO 63  63  63  PRO PRO A . n 
A 1 64  ASN 64  64  64  ASN ASN A . n 
A 1 65  SER 65  65  65  SER SER A . n 
A 1 66  ILE 66  66  66  ILE ILE A . n 
A 1 67  THR 67  67  67  THR THR A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  LEU 69  69  69  LEU LEU A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  LEU 71  71  71  LEU LEU A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  THR 77  77  77  THR THR A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  LEU 79  79  79  LEU LEU A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ILE 82  82  82  ILE ILE A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  TYR 84  84  84  TYR TYR A . n 
A 1 85  CYS 85  85  85  CYS CYS A . n 
A 1 86  PRO 86  86  86  PRO PRO A . n 
A 1 87  THR 87  87  87  THR THR A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  THR 89  89  89  THR THR A . n 
A 1 90  GLU 90  90  90  GLU GLU A . n 
A 1 91  GLU 91  91  91  GLU GLU A . n 
A 1 92  ALA 92  92  92  ALA ALA A . n 
A 1 93  PRO 93  93  93  PRO PRO A . n 
A 1 94  TYR 94  94  94  TYR TYR A . n 
A 1 95  TRP 95  95  95  TRP TRP A . n 
A 1 96  THR 96  96  96  THR THR A . n 
A 1 97  TYR 97  97  97  TYR TYR A . n 
A 1 98  LEU 98  98  98  LEU LEU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 CYS 100 100 100 CYS CYS A . n 
A 1 101 ALA 101 101 101 ALA ALA A . n 
A 1 102 LEU 102 102 102 LEU LEU A . n 
A 1 103 GLY 103 103 103 GLY GLY A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 TYR 107 107 107 TYR TYR A . n 
A 1 108 GLN 108 108 108 GLN GLN A . n 
A 1 109 SER 109 109 109 SER SER A . n 
A 1 110 LEU 110 110 110 LEU LEU A . n 
A 1 111 ASP 111 111 111 ASP ASP A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 ILE 113 113 113 ILE ILE A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 LYS 116 116 116 LYS LYS A . n 
A 1 117 GLN 117 117 117 GLN GLN A . n 
A 1 118 ALA 118 118 118 ALA ALA A . n 
A 1 119 ARG 119 119 119 ARG ARG A . n 
A 1 120 ARG 120 120 120 ARG ARG A . n 
A 1 121 THR 121 121 121 THR THR A . n 
A 1 122 ASN 122 122 122 ASN ASN A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 CYS 124 124 124 CYS CYS A . n 
A 1 125 SER 125 125 125 SER SER A . n 
A 1 126 PRO 126 126 126 PRO PRO A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 HIS 133 133 133 HIS HIS A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 CYS 135 135 135 CYS CYS A . n 
A 1 136 ASP 136 136 136 ASP ASP A . n 
A 1 137 SER 137 137 137 SER SER A . n 
A 1 138 LEU 138 138 138 LEU LEU A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 MET 143 143 143 MET MET A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 SER 148 148 148 SER SER A . n 
A 1 149 ILE 149 149 149 ILE ILE A . n 
A 1 150 ALA 150 150 150 ALA ALA A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 THR 155 155 155 THR THR A . n 
A 1 156 TYR 156 156 156 TYR TYR A . n 
A 1 157 PRO 157 157 157 PRO PRO A . n 
A 1 158 ASP 158 158 158 ASP ASP A . n 
A 1 159 TRP 159 159 159 TRP TRP A . n 
A 1 160 PHE 160 160 160 PHE PHE A . n 
A 1 161 PHE 161 161 161 PHE PHE A . n 
A 1 162 PHE 162 162 162 PHE PHE A . n 
A 1 163 CYS 163 163 163 CYS CYS A . n 
A 1 164 SER 164 164 164 SER SER A . n 
A 1 165 PHE 165 165 165 PHE PHE A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 GLY 167 167 167 GLY GLY A . n 
A 1 168 MET 168 168 168 MET MET A . n 
A 1 169 PHE 169 169 169 PHE PHE A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 PHE 171 171 171 PHE PHE A . n 
A 1 172 TYR 172 172 172 TYR TYR A . n 
A 1 173 CYS 173 173 173 CYS CYS A . n 
A 1 174 ALA 174 174 174 ALA ALA A . n 
A 1 175 HIS 175 175 175 HIS HIS A . n 
A 1 176 TRP 176 176 176 TRP TRP A . n 
A 1 177 GLN 177 177 177 GLN GLN A . n 
A 1 178 THR 178 178 178 THR THR A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 VAL 180 180 180 VAL VAL A . n 
A 1 181 SER 181 181 181 SER SER A . n 
A 1 182 GLY 182 182 182 GLY GLY A . n 
A 1 183 MET 183 183 183 MET MET A . n 
A 1 184 LEU 184 184 184 LEU LEU A . n 
A 1 185 ARG 185 185 185 ARG ARG A . n 
A 1 186 PHE 186 186 186 PHE PHE A . n 
A 1 187 GLY 187 187 187 GLY GLY A . n 
A 1 188 LYS 188 188 188 LYS LYS A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 ASP 190 190 190 ASP ASP A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 THR 192 192 192 THR THR A . n 
A 1 193 GLU 193 193 193 GLU GLU A . n 
A 1 194 ILE 194 194 194 ILE ILE A . n 
A 1 195 GLN 195 195 195 GLN GLN A . n 
A 1 196 ILE 196 196 196 ILE ILE A . n 
A 1 197 ALA 197 197 197 ALA ALA A . n 
A 1 198 LEU 198 198 198 LEU LEU A . n 
A 1 199 VAL 199 199 199 VAL VAL A . n 
A 1 200 ILE 200 200 200 ILE ILE A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 PHE 202 202 202 PHE PHE A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 PHE 207 207 207 PHE PHE A . n 
A 1 208 GLY 208 208 208 GLY GLY A . n 
A 1 209 GLY 209 209 209 GLY GLY A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 MET 212 212 212 MET MET A . n 
A 1 213 TRP 213 213 213 TRP TRP A . n 
A 1 214 ASP 214 214 214 ASP ASP A . n 
A 1 215 TYR 215 215 215 TYR TYR A . n 
A 1 216 THR 216 216 216 THR THR A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 ILE 219 219 219 ILE ILE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 GLU 221 221 221 GLU GLU A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 LEU 224 224 224 LEU LEU A . n 
A 1 225 LYS 225 225 225 LYS LYS A . n 
A 1 226 ILE 226 226 226 ILE ILE A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 PRO 228 228 228 PRO PRO A . n 
A 1 229 VAL 229 229 229 VAL VAL A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 PHE 232 232 232 PHE PHE A . n 
A 1 233 LEU 233 233 233 LEU LEU A . n 
A 1 234 GLY 234 234 234 GLY GLY A . n 
A 1 235 GLY 235 235 235 GLY GLY A . n 
A 1 236 VAL 236 236 236 VAL VAL A . n 
A 1 237 ILE 237 237 237 ILE ILE A . n 
A 1 238 PHE 238 238 238 PHE PHE A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 CYS 240 240 240 CYS CYS A . n 
A 1 241 SER 241 241 241 SER SER A . n 
A 1 242 ASN 242 242 242 ASN ASN A . n 
A 1 243 TYR 243 243 243 TYR TYR A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 ILE 247 247 247 ILE ILE A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 HIS 249 249 249 HIS HIS A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 VAL 252 252 252 VAL VAL A . n 
A 1 253 GLY 253 253 253 GLY GLY A . n 
A 1 254 LYS 254 254 254 LYS LYS A . n 
A 1 255 ASN 255 255 255 ASN ASN A . n 
A 1 256 GLY 256 256 256 GLY GLY A . n 
A 1 257 SER 257 257 257 SER SER A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 GLY 261 261 261 GLY GLY A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 VAL 264 264 264 VAL VAL A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 PRO 267 267 267 PRO PRO A . n 
A 1 268 GLY 268 268 268 GLY GLY A . n 
A 1 269 LEU 269 269 269 LEU LEU A . n 
A 1 270 HIS 270 270 270 HIS HIS A . n 
A 1 271 ILE 271 271 271 ILE ILE A . n 
A 1 272 GLY 272 272 272 GLY GLY A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 ILE 274 274 274 ILE ILE A . n 
A 1 275 ILE 275 275 275 ILE ILE A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 LEU 277 277 277 LEU LEU A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 ILE 279 279 279 ILE ILE A . n 
A 1 280 MET 280 280 280 MET MET A . n 
A 1 281 ILE 281 281 281 ILE ILE A . n 
A 1 282 TYR 282 282 282 TYR TYR A . n 
A 1 283 LYS 283 283 283 LYS LYS A . n 
A 1 284 LYS 284 284 284 LYS LYS A . n 
A 1 285 SER 285 285 285 SER SER A . n 
A 1 286 ALA 286 286 286 ALA ALA A . n 
A 1 287 THR 287 287 287 THR THR A . n 
A 1 288 ASP 288 288 288 ASP ASP A . n 
A 1 289 VAL 289 289 289 VAL VAL A . n 
A 1 290 PHE 290 290 290 PHE PHE A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 LYS 292 292 292 LYS LYS A . n 
A 1 293 HIS 293 293 293 HIS HIS A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 CYS 295 295 295 CYS CYS A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 ILE 298 298 298 ILE ILE A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 MET 300 300 300 MET MET A . n 
A 1 301 PHE 301 301 301 PHE PHE A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 CYS 303 303 303 CYS CYS A . n 
A 1 304 VAL 304 304 304 VAL VAL A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 LYS 307 307 307 LYS LYS A . n 
A 1 308 VAL 308 308 308 VAL VAL A . n 
A 1 309 SER 309 309 309 SER SER A . n 
A 1 310 GLN 310 310 310 GLN GLN A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 VAL 313 313 313 VAL VAL A . n 
A 1 314 VAL 314 314 314 VAL VAL A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 HIS 316 316 316 HIS HIS A . n 
A 1 317 MET 317 317 317 MET MET A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 LYS 319 319 319 LYS LYS A . n 
A 1 320 SER 320 320 320 SER SER A . n 
A 1 321 GLU 321 321 321 GLU GLU A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 TYR 323 323 323 TYR TYR A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 ASP 326 326 326 ASP ASP A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 VAL 328 328 328 VAL VAL A . n 
A 1 329 PHE 329 329 329 PHE PHE A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 GLY 331 331 331 GLY GLY A . n 
A 1 332 PRO 332 332 332 PRO PRO A . n 
A 1 333 GLY 333 333 333 GLY GLY A . n 
A 1 334 LEU 334 334 334 LEU LEU A . n 
A 1 335 LEU 335 335 335 LEU LEU A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 ASP 338 338 338 ASP ASP A . n 
A 1 339 GLN 339 339 339 GLN GLN A . n 
A 1 340 TYR 340 340 340 TYR TYR A . n 
A 1 341 PHE 341 341 341 PHE PHE A . n 
A 1 342 ASN 342 342 342 ASN ASN A . n 
A 1 343 ASN 343 343 343 ASN ASN A . n 
A 1 344 PHE 344 344 344 PHE PHE A . n 
A 1 345 ILE 345 345 345 ILE ILE A . n 
A 1 346 ASP 346 346 346 ASP ASP A . n 
A 1 347 GLU 347 347 347 GLU GLU A . n 
A 1 348 TYR 348 348 348 TYR TYR A . n 
A 1 349 VAL 349 349 349 VAL VAL A . n 
A 1 350 VAL 350 350 350 VAL VAL A . n 
A 1 351 LEU 351 351 351 LEU LEU A . n 
A 1 352 TRP 352 352 352 TRP TRP A . n 
A 1 353 MET 353 353 353 MET MET A . n 
A 1 354 ALA 354 354 354 ALA ALA A . n 
A 1 355 MET 355 355 355 MET MET A . n 
A 1 356 VAL 356 356 356 VAL VAL A . n 
A 1 357 ILE 357 357 357 ILE ILE A . n 
A 1 358 SER 358 358 358 SER SER A . n 
A 1 359 SER 359 359 359 SER SER A . n 
A 1 360 PHE 360 360 360 PHE PHE A . n 
A 1 361 ASP 361 361 361 ASP ASP A . n 
A 1 362 MET 362 362 362 MET MET A . n 
A 1 363 VAL 363 363 363 VAL VAL A . n 
A 1 364 ILE 364 364 364 ILE ILE A . n 
A 1 365 TYR 365 365 365 TYR TYR A . n 
A 1 366 PHE 366 366 366 PHE PHE A . n 
A 1 367 SER 367 367 367 SER SER A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 CYS 370 370 370 CYS CYS A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 GLN 372 372 372 GLN GLN A . n 
A 1 373 ILE 373 373 373 ILE ILE A . n 
A 1 374 SER 374 374 374 SER SER A . n 
A 1 375 ARG 375 375 375 ARG ARG A . n 
A 1 376 HIS 376 376 376 HIS HIS A . n 
A 1 377 LEU 377 377 377 LEU LEU A . n 
A 1 378 HIS 378 378 378 HIS HIS A . n 
A 1 379 LEU 379 379 379 LEU LEU A . n 
A 1 380 ASN 380 380 380 ASN ASN A . n 
A 1 381 ILE 381 381 381 ILE ILE A . n 
A 1 382 PHE 382 382 382 PHE PHE A . n 
A 1 383 LYS 383 383 383 LYS LYS A . n 
A 1 384 THR 384 384 ?   ?   ?   A . n 
A 1 385 ALA 385 385 ?   ?   ?   A . n 
A 1 386 CYS 386 386 ?   ?   ?   A . n 
A 1 387 HIS 387 387 ?   ?   ?   A . n 
A 1 388 GLN 388 388 ?   ?   ?   A . n 
A 1 389 ALA 389 389 ?   ?   ?   A . n 
A 1 390 PRO 390 390 ?   ?   ?   A . n 
A 1 391 GLU 391 391 ?   ?   ?   A . n 
A 1 392 GLN 392 392 ?   ?   ?   A . n 
A 1 393 VAL 393 393 ?   ?   ?   A . n 
A 1 394 GLN 394 394 ?   ?   ?   A . n 
A 1 395 VAL 395 395 ?   ?   ?   A . n 
A 1 396 LEU 396 396 ?   ?   ?   A . n 
A 1 397 SER 397 397 ?   ?   ?   A . n 
A 1 398 SER 398 398 ?   ?   ?   A . n 
A 1 399 LYS 399 399 ?   ?   ?   A . n 
A 1 400 SER 400 400 ?   ?   ?   A . n 
A 1 401 HIS 401 401 ?   ?   ?   A . n 
A 1 402 GLN 402 402 ?   ?   ?   A . n 
A 1 403 ASN 403 403 ?   ?   ?   A . n 
A 1 404 ASN 404 404 ?   ?   ?   A . n 
A 1 405 MET 405 405 ?   ?   ?   A . n 
A 1 406 ASP 406 406 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   ALA 3   3   ?   ?   ?   B . n 
B 1 4   GLY 4   4   ?   ?   ?   B . n 
B 1 5   ALA 5   5   ?   ?   ?   B . n 
B 1 6   GLY 6   6   ?   ?   ?   B . n 
B 1 7   ALA 7   7   ?   ?   ?   B . n 
B 1 8   GLY 8   8   ?   ?   ?   B . n 
B 1 9   SER 9   9   ?   ?   ?   B . n 
B 1 10  ALA 10  10  ?   ?   ?   B . n 
B 1 11  PRO 11  11  ?   ?   ?   B . n 
B 1 12  ARG 12  12  ?   ?   ?   B . n 
B 1 13  TRP 13  13  ?   ?   ?   B . n 
B 1 14  LEU 14  14  ?   ?   ?   B . n 
B 1 15  ARG 15  15  ?   ?   ?   B . n 
B 1 16  ALA 16  16  16  ALA ALA B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  SER 18  18  18  SER SER B . n 
B 1 19  GLU 19  19  19  GLU GLU B . n 
B 1 20  PRO 20  20  20  PRO PRO B . n 
B 1 21  LEU 21  21  21  LEU LEU B . n 
B 1 22  SER 22  22  22  SER SER B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  ALA 24  24  24  ALA ALA B . n 
B 1 25  GLN 25  25  25  GLN GLN B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  ARG 27  27  27  ARG ARG B . n 
B 1 28  ARG 28  28  28  ARG ARG B . n 
B 1 29  LEU 29  29  29  LEU LEU B . n 
B 1 30  GLU 30  30  30  GLU GLU B . n 
B 1 31  GLU 31  31  31  GLU GLU B . n 
B 1 32  HIS 32  32  32  HIS HIS B . n 
B 1 33  ARG 33  33  33  ARG ARG B . n 
B 1 34  TYR 34  34  34  TYR TYR B . n 
B 1 35  SER 35  35  35  SER SER B . n 
B 1 36  ALA 36  36  36  ALA ALA B . n 
B 1 37  ALA 37  37  37  ALA ALA B . n 
B 1 38  GLY 38  38  38  GLY GLY B . n 
B 1 39  VAL 39  39  39  VAL VAL B . n 
B 1 40  SER 40  40  40  SER SER B . n 
B 1 41  LEU 41  41  41  LEU LEU B . n 
B 1 42  LEU 42  42  42  LEU LEU B . n 
B 1 43  GLU 43  43  43  GLU GLU B . n 
B 1 44  PRO 44  44  44  PRO PRO B . n 
B 1 45  PRO 45  45  45  PRO PRO B . n 
B 1 46  LEU 46  46  46  LEU LEU B . n 
B 1 47  GLN 47  47  47  GLN GLN B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  TYR 49  49  49  TYR TYR B . n 
B 1 50  TRP 50  50  50  TRP TRP B . n 
B 1 51  THR 51  51  51  THR THR B . n 
B 1 52  TRP 52  52  52  TRP TRP B . n 
B 1 53  LEU 53  53  53  LEU LEU B . n 
B 1 54  LEU 54  54  54  LEU LEU B . n 
B 1 55  GLN 55  55  55  GLN GLN B . n 
B 1 56  TRP 56  56  56  TRP TRP B . n 
B 1 57  ILE 57  57  57  ILE ILE B . n 
B 1 58  PRO 58  58  58  PRO PRO B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  TRP 60  60  60  TRP TRP B . n 
B 1 61  MET 61  61  61  MET MET B . n 
B 1 62  ALA 62  62  62  ALA ALA B . n 
B 1 63  PRO 63  63  63  PRO PRO B . n 
B 1 64  ASN 64  64  64  ASN ASN B . n 
B 1 65  SER 65  65  65  SER SER B . n 
B 1 66  ILE 66  66  66  ILE ILE B . n 
B 1 67  THR 67  67  67  THR THR B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  LEU 69  69  69  LEU LEU B . n 
B 1 70  GLY 70  70  70  GLY GLY B . n 
B 1 71  LEU 71  71  71  LEU LEU B . n 
B 1 72  ALA 72  72  72  ALA ALA B . n 
B 1 73  VAL 73  73  73  VAL VAL B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  VAL 75  75  75  VAL VAL B . n 
B 1 76  VAL 76  76  76  VAL VAL B . n 
B 1 77  THR 77  77  77  THR THR B . n 
B 1 78  THR 78  78  78  THR THR B . n 
B 1 79  LEU 79  79  79  LEU LEU B . n 
B 1 80  VAL 80  80  80  VAL VAL B . n 
B 1 81  LEU 81  81  81  LEU LEU B . n 
B 1 82  ILE 82  82  82  ILE ILE B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  TYR 84  84  84  TYR TYR B . n 
B 1 85  CYS 85  85  85  CYS CYS B . n 
B 1 86  PRO 86  86  86  PRO PRO B . n 
B 1 87  THR 87  87  87  THR THR B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  THR 89  89  89  THR THR B . n 
B 1 90  GLU 90  90  90  GLU GLU B . n 
B 1 91  GLU 91  91  91  GLU GLU B . n 
B 1 92  ALA 92  92  92  ALA ALA B . n 
B 1 93  PRO 93  93  93  PRO PRO B . n 
B 1 94  TYR 94  94  94  TYR TYR B . n 
B 1 95  TRP 95  95  95  TRP TRP B . n 
B 1 96  THR 96  96  96  THR THR B . n 
B 1 97  TYR 97  97  97  TYR TYR B . n 
B 1 98  LEU 98  98  98  LEU LEU B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 CYS 100 100 100 CYS CYS B . n 
B 1 101 ALA 101 101 101 ALA ALA B . n 
B 1 102 LEU 102 102 102 LEU LEU B . n 
B 1 103 GLY 103 103 103 GLY GLY B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 TYR 107 107 107 TYR TYR B . n 
B 1 108 GLN 108 108 108 GLN GLN B . n 
B 1 109 SER 109 109 109 SER SER B . n 
B 1 110 LEU 110 110 110 LEU LEU B . n 
B 1 111 ASP 111 111 111 ASP ASP B . n 
B 1 112 ALA 112 112 112 ALA ALA B . n 
B 1 113 ILE 113 113 113 ILE ILE B . n 
B 1 114 ASP 114 114 114 ASP ASP B . n 
B 1 115 GLY 115 115 115 GLY GLY B . n 
B 1 116 LYS 116 116 116 LYS LYS B . n 
B 1 117 GLN 117 117 117 GLN GLN B . n 
B 1 118 ALA 118 118 118 ALA ALA B . n 
B 1 119 ARG 119 119 119 ARG ARG B . n 
B 1 120 ARG 120 120 120 ARG ARG B . n 
B 1 121 THR 121 121 121 THR THR B . n 
B 1 122 ASN 122 122 122 ASN ASN B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 CYS 124 124 124 CYS CYS B . n 
B 1 125 SER 125 125 125 SER SER B . n 
B 1 126 PRO 126 126 126 PRO PRO B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 GLU 129 129 129 GLU GLU B . n 
B 1 130 LEU 130 130 130 LEU LEU B . n 
B 1 131 PHE 131 131 131 PHE PHE B . n 
B 1 132 ASP 132 132 132 ASP ASP B . n 
B 1 133 HIS 133 133 133 HIS HIS B . n 
B 1 134 GLY 134 134 134 GLY GLY B . n 
B 1 135 CYS 135 135 135 CYS CYS B . n 
B 1 136 ASP 136 136 136 ASP ASP B . n 
B 1 137 SER 137 137 137 SER SER B . n 
B 1 138 LEU 138 138 138 LEU LEU B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 VAL 141 141 141 VAL VAL B . n 
B 1 142 PHE 142 142 142 PHE PHE B . n 
B 1 143 MET 143 143 143 MET MET B . n 
B 1 144 ALA 144 144 144 ALA ALA B . n 
B 1 145 VAL 145 145 145 VAL VAL B . n 
B 1 146 GLY 146 146 146 GLY GLY B . n 
B 1 147 ALA 147 147 147 ALA ALA B . n 
B 1 148 SER 148 148 148 SER SER B . n 
B 1 149 ILE 149 149 149 ILE ILE B . n 
B 1 150 ALA 150 150 150 ALA ALA B . n 
B 1 151 ALA 151 151 151 ALA ALA B . n 
B 1 152 ARG 152 152 152 ARG ARG B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 GLY 154 154 154 GLY GLY B . n 
B 1 155 THR 155 155 155 THR THR B . n 
B 1 156 TYR 156 156 156 TYR TYR B . n 
B 1 157 PRO 157 157 157 PRO PRO B . n 
B 1 158 ASP 158 158 158 ASP ASP B . n 
B 1 159 TRP 159 159 159 TRP TRP B . n 
B 1 160 PHE 160 160 160 PHE PHE B . n 
B 1 161 PHE 161 161 161 PHE PHE B . n 
B 1 162 PHE 162 162 162 PHE PHE B . n 
B 1 163 CYS 163 163 163 CYS CYS B . n 
B 1 164 SER 164 164 164 SER SER B . n 
B 1 165 PHE 165 165 165 PHE PHE B . n 
B 1 166 ILE 166 166 166 ILE ILE B . n 
B 1 167 GLY 167 167 167 GLY GLY B . n 
B 1 168 MET 168 168 168 MET MET B . n 
B 1 169 PHE 169 169 169 PHE PHE B . n 
B 1 170 VAL 170 170 170 VAL VAL B . n 
B 1 171 PHE 171 171 171 PHE PHE B . n 
B 1 172 TYR 172 172 172 TYR TYR B . n 
B 1 173 CYS 173 173 173 CYS CYS B . n 
B 1 174 ALA 174 174 174 ALA ALA B . n 
B 1 175 HIS 175 175 175 HIS HIS B . n 
B 1 176 TRP 176 176 176 TRP TRP B . n 
B 1 177 GLN 177 177 177 GLN GLN B . n 
B 1 178 THR 178 178 178 THR THR B . n 
B 1 179 TYR 179 179 179 TYR TYR B . n 
B 1 180 VAL 180 180 180 VAL VAL B . n 
B 1 181 SER 181 181 181 SER SER B . n 
B 1 182 GLY 182 182 182 GLY GLY B . n 
B 1 183 MET 183 183 183 MET MET B . n 
B 1 184 LEU 184 184 184 LEU LEU B . n 
B 1 185 ARG 185 185 185 ARG ARG B . n 
B 1 186 PHE 186 186 186 PHE PHE B . n 
B 1 187 GLY 187 187 187 GLY GLY B . n 
B 1 188 LYS 188 188 188 LYS LYS B . n 
B 1 189 VAL 189 189 189 VAL VAL B . n 
B 1 190 ASP 190 190 190 ASP ASP B . n 
B 1 191 VAL 191 191 191 VAL VAL B . n 
B 1 192 THR 192 192 192 THR THR B . n 
B 1 193 GLU 193 193 193 GLU GLU B . n 
B 1 194 ILE 194 194 194 ILE ILE B . n 
B 1 195 GLN 195 195 195 GLN GLN B . n 
B 1 196 ILE 196 196 196 ILE ILE B . n 
B 1 197 ALA 197 197 197 ALA ALA B . n 
B 1 198 LEU 198 198 198 LEU LEU B . n 
B 1 199 VAL 199 199 199 VAL VAL B . n 
B 1 200 ILE 200 200 200 ILE ILE B . n 
B 1 201 VAL 201 201 201 VAL VAL B . n 
B 1 202 PHE 202 202 202 PHE PHE B . n 
B 1 203 VAL 203 203 203 VAL VAL B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 SER 205 205 205 SER SER B . n 
B 1 206 ALA 206 206 206 ALA ALA B . n 
B 1 207 PHE 207 207 207 PHE PHE B . n 
B 1 208 GLY 208 208 208 GLY GLY B . n 
B 1 209 GLY 209 209 209 GLY GLY B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 THR 211 211 211 THR THR B . n 
B 1 212 MET 212 212 212 MET MET B . n 
B 1 213 TRP 213 213 213 TRP TRP B . n 
B 1 214 ASP 214 214 214 ASP ASP B . n 
B 1 215 TYR 215 215 215 TYR TYR B . n 
B 1 216 THR 216 216 216 THR THR B . n 
B 1 217 ILE 217 217 217 ILE ILE B . n 
B 1 218 PRO 218 218 218 PRO PRO B . n 
B 1 219 ILE 219 219 219 ILE ILE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 GLU 221 221 221 GLU GLU B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 LYS 223 223 223 LYS LYS B . n 
B 1 224 LEU 224 224 224 LEU LEU B . n 
B 1 225 LYS 225 225 225 LYS LYS B . n 
B 1 226 ILE 226 226 226 ILE ILE B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 PRO 228 228 228 PRO PRO B . n 
B 1 229 VAL 229 229 229 VAL VAL B . n 
B 1 230 LEU 230 230 230 LEU LEU B . n 
B 1 231 GLY 231 231 231 GLY GLY B . n 
B 1 232 PHE 232 232 232 PHE PHE B . n 
B 1 233 LEU 233 233 233 LEU LEU B . n 
B 1 234 GLY 234 234 234 GLY GLY B . n 
B 1 235 GLY 235 235 235 GLY GLY B . n 
B 1 236 VAL 236 236 236 VAL VAL B . n 
B 1 237 ILE 237 237 237 ILE ILE B . n 
B 1 238 PHE 238 238 238 PHE PHE B . n 
B 1 239 SER 239 239 239 SER SER B . n 
B 1 240 CYS 240 240 240 CYS CYS B . n 
B 1 241 SER 241 241 241 SER SER B . n 
B 1 242 ASN 242 242 242 ASN ASN B . n 
B 1 243 TYR 243 243 243 TYR TYR B . n 
B 1 244 PHE 244 244 244 PHE PHE B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 VAL 246 246 246 VAL VAL B . n 
B 1 247 ILE 247 247 247 ILE ILE B . n 
B 1 248 LEU 248 248 248 LEU LEU B . n 
B 1 249 HIS 249 249 249 HIS HIS B . n 
B 1 250 GLY 250 250 250 GLY GLY B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 VAL 252 252 252 VAL VAL B . n 
B 1 253 GLY 253 253 253 GLY GLY B . n 
B 1 254 LYS 254 254 254 LYS LYS B . n 
B 1 255 ASN 255 255 255 ASN ASN B . n 
B 1 256 GLY 256 256 256 GLY GLY B . n 
B 1 257 SER 257 257 257 SER SER B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 ILE 259 259 259 ILE ILE B . n 
B 1 260 ALA 260 260 260 ALA ALA B . n 
B 1 261 GLY 261 261 261 GLY GLY B . n 
B 1 262 THR 262 262 262 THR THR B . n 
B 1 263 SER 263 263 263 SER SER B . n 
B 1 264 VAL 264 264 264 VAL VAL B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 SER 266 266 266 SER SER B . n 
B 1 267 PRO 267 267 267 PRO PRO B . n 
B 1 268 GLY 268 268 268 GLY GLY B . n 
B 1 269 LEU 269 269 269 LEU LEU B . n 
B 1 270 HIS 270 270 270 HIS HIS B . n 
B 1 271 ILE 271 271 271 ILE ILE B . n 
B 1 272 GLY 272 272 272 GLY GLY B . n 
B 1 273 LEU 273 273 273 LEU LEU B . n 
B 1 274 ILE 274 274 274 ILE ILE B . n 
B 1 275 ILE 275 275 275 ILE ILE B . n 
B 1 276 ILE 276 276 276 ILE ILE B . n 
B 1 277 LEU 277 277 277 LEU LEU B . n 
B 1 278 ALA 278 278 278 ALA ALA B . n 
B 1 279 ILE 279 279 279 ILE ILE B . n 
B 1 280 MET 280 280 280 MET MET B . n 
B 1 281 ILE 281 281 281 ILE ILE B . n 
B 1 282 TYR 282 282 282 TYR TYR B . n 
B 1 283 LYS 283 283 283 LYS LYS B . n 
B 1 284 LYS 284 284 284 LYS LYS B . n 
B 1 285 SER 285 285 285 SER SER B . n 
B 1 286 ALA 286 286 286 ALA ALA B . n 
B 1 287 THR 287 287 287 THR THR B . n 
B 1 288 ASP 288 288 288 ASP ASP B . n 
B 1 289 VAL 289 289 289 VAL VAL B . n 
B 1 290 PHE 290 290 290 PHE PHE B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 LYS 292 292 292 LYS LYS B . n 
B 1 293 HIS 293 293 293 HIS HIS B . n 
B 1 294 PRO 294 294 294 PRO PRO B . n 
B 1 295 CYS 295 295 295 CYS CYS B . n 
B 1 296 LEU 296 296 296 LEU LEU B . n 
B 1 297 TYR 297 297 297 TYR TYR B . n 
B 1 298 ILE 298 298 298 ILE ILE B . n 
B 1 299 LEU 299 299 299 LEU LEU B . n 
B 1 300 MET 300 300 300 MET MET B . n 
B 1 301 PHE 301 301 301 PHE PHE B . n 
B 1 302 GLY 302 302 302 GLY GLY B . n 
B 1 303 CYS 303 303 303 CYS CYS B . n 
B 1 304 VAL 304 304 304 VAL VAL B . n 
B 1 305 PHE 305 305 305 PHE PHE B . n 
B 1 306 ALA 306 306 306 ALA ALA B . n 
B 1 307 LYS 307 307 307 LYS LYS B . n 
B 1 308 VAL 308 308 308 VAL VAL B . n 
B 1 309 SER 309 309 309 SER SER B . n 
B 1 310 GLN 310 310 310 GLN GLN B . n 
B 1 311 LYS 311 311 311 LYS LYS B . n 
B 1 312 LEU 312 312 312 LEU LEU B . n 
B 1 313 VAL 313 313 313 VAL VAL B . n 
B 1 314 VAL 314 314 314 VAL VAL B . n 
B 1 315 ALA 315 315 315 ALA ALA B . n 
B 1 316 HIS 316 316 316 HIS HIS B . n 
B 1 317 MET 317 317 317 MET MET B . n 
B 1 318 THR 318 318 318 THR THR B . n 
B 1 319 LYS 319 319 319 LYS LYS B . n 
B 1 320 SER 320 320 320 SER SER B . n 
B 1 321 GLU 321 321 321 GLU GLU B . n 
B 1 322 LEU 322 322 322 LEU LEU B . n 
B 1 323 TYR 323 323 323 TYR TYR B . n 
B 1 324 LEU 324 324 324 LEU LEU B . n 
B 1 325 GLN 325 325 325 GLN GLN B . n 
B 1 326 ASP 326 326 326 ASP ASP B . n 
B 1 327 THR 327 327 327 THR THR B . n 
B 1 328 VAL 328 328 328 VAL VAL B . n 
B 1 329 PHE 329 329 329 PHE PHE B . n 
B 1 330 LEU 330 330 330 LEU LEU B . n 
B 1 331 GLY 331 331 331 GLY GLY B . n 
B 1 332 PRO 332 332 332 PRO PRO B . n 
B 1 333 GLY 333 333 333 GLY GLY B . n 
B 1 334 LEU 334 334 334 LEU LEU B . n 
B 1 335 LEU 335 335 335 LEU LEU B . n 
B 1 336 PHE 336 336 336 PHE PHE B . n 
B 1 337 LEU 337 337 337 LEU LEU B . n 
B 1 338 ASP 338 338 338 ASP ASP B . n 
B 1 339 GLN 339 339 339 GLN GLN B . n 
B 1 340 TYR 340 340 340 TYR TYR B . n 
B 1 341 PHE 341 341 341 PHE PHE B . n 
B 1 342 ASN 342 342 342 ASN ASN B . n 
B 1 343 ASN 343 343 343 ASN ASN B . n 
B 1 344 PHE 344 344 344 PHE PHE B . n 
B 1 345 ILE 345 345 345 ILE ILE B . n 
B 1 346 ASP 346 346 346 ASP ASP B . n 
B 1 347 GLU 347 347 347 GLU GLU B . n 
B 1 348 TYR 348 348 348 TYR TYR B . n 
B 1 349 VAL 349 349 349 VAL VAL B . n 
B 1 350 VAL 350 350 350 VAL VAL B . n 
B 1 351 LEU 351 351 351 LEU LEU B . n 
B 1 352 TRP 352 352 352 TRP TRP B . n 
B 1 353 MET 353 353 353 MET MET B . n 
B 1 354 ALA 354 354 354 ALA ALA B . n 
B 1 355 MET 355 355 355 MET MET B . n 
B 1 356 VAL 356 356 356 VAL VAL B . n 
B 1 357 ILE 357 357 357 ILE ILE B . n 
B 1 358 SER 358 358 358 SER SER B . n 
B 1 359 SER 359 359 359 SER SER B . n 
B 1 360 PHE 360 360 360 PHE PHE B . n 
B 1 361 ASP 361 361 361 ASP ASP B . n 
B 1 362 MET 362 362 362 MET MET B . n 
B 1 363 VAL 363 363 363 VAL VAL B . n 
B 1 364 ILE 364 364 364 ILE ILE B . n 
B 1 365 TYR 365 365 365 TYR TYR B . n 
B 1 366 PHE 366 366 366 PHE PHE B . n 
B 1 367 SER 367 367 367 SER SER B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 CYS 370 370 370 CYS CYS B . n 
B 1 371 LEU 371 371 371 LEU LEU B . n 
B 1 372 GLN 372 372 372 GLN GLN B . n 
B 1 373 ILE 373 373 373 ILE ILE B . n 
B 1 374 SER 374 374 374 SER SER B . n 
B 1 375 ARG 375 375 375 ARG ARG B . n 
B 1 376 HIS 376 376 376 HIS HIS B . n 
B 1 377 LEU 377 377 377 LEU LEU B . n 
B 1 378 HIS 378 378 378 HIS HIS B . n 
B 1 379 LEU 379 379 379 LEU LEU B . n 
B 1 380 ASN 380 380 380 ASN ASN B . n 
B 1 381 ILE 381 381 381 ILE ILE B . n 
B 1 382 PHE 382 382 382 PHE PHE B . n 
B 1 383 LYS 383 383 383 LYS LYS B . n 
B 1 384 THR 384 384 ?   ?   ?   B . n 
B 1 385 ALA 385 385 ?   ?   ?   B . n 
B 1 386 CYS 386 386 ?   ?   ?   B . n 
B 1 387 HIS 387 387 ?   ?   ?   B . n 
B 1 388 GLN 388 388 ?   ?   ?   B . n 
B 1 389 ALA 389 389 ?   ?   ?   B . n 
B 1 390 PRO 390 390 ?   ?   ?   B . n 
B 1 391 GLU 391 391 ?   ?   ?   B . n 
B 1 392 GLN 392 392 ?   ?   ?   B . n 
B 1 393 VAL 393 393 ?   ?   ?   B . n 
B 1 394 GLN 394 394 ?   ?   ?   B . n 
B 1 395 VAL 395 395 ?   ?   ?   B . n 
B 1 396 LEU 396 396 ?   ?   ?   B . n 
B 1 397 SER 397 397 ?   ?   ?   B . n 
B 1 398 SER 398 398 ?   ?   ?   B . n 
B 1 399 LYS 399 399 ?   ?   ?   B . n 
B 1 400 SER 400 400 ?   ?   ?   B . n 
B 1 401 HIS 401 401 ?   ?   ?   B . n 
B 1 402 GLN 402 402 ?   ?   ?   B . n 
B 1 403 ASN 403 403 ?   ?   ?   B . n 
B 1 404 ASN 404 404 ?   ?   ?   B . n 
B 1 405 MET 405 405 ?   ?   ?   B . n 
B 1 406 ASP 406 406 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 MG  ? ? MG  ? ? 'SUBJECT OF INVESTIGATION' ? 
2 POV ? ? POV ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 POV 1 501 401 POV POV A . 
D 3 MG  1 502 5   MG  MG  A . 
E 3 MG  1 503 6   MG  MG  A . 
F 2 POV 1 501 401 POV POV B . 
G 3 MG  1 502 7   MG  MG  B . 
H 3 MG  1 503 8   MG  MG  B . 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9UET 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9UET 
_struct.title                        'Cryo-EM structure of human choline-phosphotransferase 1' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9UET 
_struct_keywords.text            'phosphotransferase, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 3 ? 
F N N 2 ? 
G N N 3 ? 
H N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    CHPT1_HUMAN 
_struct_ref.pdbx_db_accession          Q8WUD6 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAAGAGAGSAPRWLRALSEPLSAAQLRRLEEHRYSAAGVSLLEPPLQLYWTWLLQWIPLWMAPNSITLLGLAVNVVTTLV
LISYCPTATEEAPYWTYLLCALGLFIYQSLDAIDGKQARRTNSCSPLGELFDHGCDSLSTVFMAVGASIAARLGTYPDWF
FFCSFIGMFVFYCAHWQTYVSGMLRFGKVDVTEIQIALVIVFVLSAFGGATMWDYTIPILEIKLKILPVLGFLGGVIFSC
SNYFHVILHGGVGKNGSTIAGTSVLSPGLHIGLIIILAIMIYKKSATDVFEKHPCLYILMFGCVFAKVSQKLVVAHMTKS
ELYLQDTVFLGPGLLFLDQYFNNFIDEYVVLWMAMVISSFDMVIYFSALCLQISRHLHLNIFKTACHQAPEQVQVLSSKS
HQNNMD
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9UET A 1 ? 406 ? Q8WUD6 1 ? 406 ? 1 406 
2 1 9UET B 1 ? 406 ? Q8WUD6 1 ? 406 ? 1 406 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 22  ? HIS A 32  ? SER A 22  HIS A 32  1 ? 11 
HELX_P HELX_P2  AA2 GLU A 43  ? GLN A 55  ? GLU A 43  GLN A 55  1 ? 13 
HELX_P HELX_P3  AA3 ALA A 62  ? CYS A 85  ? ALA A 62  CYS A 85  1 ? 24 
HELX_P HELX_P4  AA4 PRO A 93  ? ALA A 118 ? PRO A 93  ALA A 118 1 ? 26 
HELX_P HELX_P5  AA5 PHE A 131 ? ALA A 151 ? PHE A 131 ALA A 151 1 ? 21 
HELX_P HELX_P6  AA6 ARG A 152 ? THR A 155 ? ARG A 152 THR A 155 5 ? 4  
HELX_P HELX_P7  AA7 TYR A 156 ? VAL A 180 ? TYR A 156 VAL A 180 1 ? 25 
HELX_P HELX_P8  AA8 ASP A 190 ? GLY A 208 ? ASP A 190 GLY A 208 1 ? 19 
HELX_P HELX_P9  AA9 GLY A 209 ? TYR A 215 ? GLY A 209 TYR A 215 5 ? 7  
HELX_P HELX_P10 AB1 ILE A 226 ? LEU A 248 ? ILE A 226 LEU A 248 1 ? 23 
HELX_P HELX_P11 AB2 PRO A 267 ? SER A 285 ? PRO A 267 SER A 285 1 ? 19 
HELX_P HELX_P12 AB3 ASP A 288 ? HIS A 293 ? ASP A 288 HIS A 293 1 ? 6  
HELX_P HELX_P13 AB4 LEU A 296 ? THR A 318 ? LEU A 296 THR A 318 1 ? 23 
HELX_P HELX_P14 AB5 ASP A 326 ? VAL A 328 ? ASP A 326 VAL A 328 5 ? 3  
HELX_P HELX_P15 AB6 PHE A 329 ? PHE A 341 ? PHE A 329 PHE A 341 1 ? 13 
HELX_P HELX_P16 AB7 ASP A 346 ? LEU A 377 ? ASP A 346 LEU A 377 1 ? 32 
HELX_P HELX_P17 AB8 SER B 22  ? HIS B 32  ? SER B 22  HIS B 32  1 ? 11 
HELX_P HELX_P18 AB9 GLU B 43  ? GLN B 55  ? GLU B 43  GLN B 55  1 ? 13 
HELX_P HELX_P19 AC1 ALA B 62  ? CYS B 85  ? ALA B 62  CYS B 85  1 ? 24 
HELX_P HELX_P20 AC2 PRO B 93  ? ALA B 118 ? PRO B 93  ALA B 118 1 ? 26 
HELX_P HELX_P21 AC3 PHE B 131 ? ALA B 151 ? PHE B 131 ALA B 151 1 ? 21 
HELX_P HELX_P22 AC4 ARG B 152 ? THR B 155 ? ARG B 152 THR B 155 5 ? 4  
HELX_P HELX_P23 AC5 TYR B 156 ? VAL B 180 ? TYR B 156 VAL B 180 1 ? 25 
HELX_P HELX_P24 AC6 ASP B 190 ? GLY B 208 ? ASP B 190 GLY B 208 1 ? 19 
HELX_P HELX_P25 AC7 GLY B 209 ? TYR B 215 ? GLY B 209 TYR B 215 5 ? 7  
HELX_P HELX_P26 AC8 ILE B 226 ? LEU B 248 ? ILE B 226 LEU B 248 1 ? 23 
HELX_P HELX_P27 AC9 PRO B 267 ? SER B 285 ? PRO B 267 SER B 285 1 ? 19 
HELX_P HELX_P28 AD1 ASP B 288 ? HIS B 293 ? ASP B 288 HIS B 293 1 ? 6  
HELX_P HELX_P29 AD2 LEU B 296 ? THR B 318 ? LEU B 296 THR B 318 1 ? 23 
HELX_P HELX_P30 AD3 ASP B 326 ? VAL B 328 ? ASP B 326 VAL B 328 5 ? 3  
HELX_P HELX_P31 AD4 PHE B 329 ? PHE B 341 ? PHE B 329 PHE B 341 1 ? 13 
HELX_P HELX_P32 AD5 ASP B 346 ? LEU B 377 ? ASP B 346 LEU B 377 1 ? 32 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 111 OD1 ? ? ? 1_555 D MG . MG ? ? A ASP 111 A MG 502 1_555 ? ? ? ? ? ? ? 2.651 ? ? 
metalc2  metalc ? ? A ASP 111 OD2 ? ? ? 1_555 D MG . MG ? ? A ASP 111 A MG 502 1_555 ? ? ? ? ? ? ? 2.413 ? ? 
metalc3  metalc ? ? A ASP 114 OD1 ? ? ? 1_555 E MG . MG ? ? A ASP 114 A MG 503 1_555 ? ? ? ? ? ? ? 2.075 ? ? 
metalc4  metalc ? ? A ASP 114 OD2 ? ? ? 1_555 E MG . MG ? ? A ASP 114 A MG 503 1_555 ? ? ? ? ? ? ? 2.570 ? ? 
metalc5  metalc ? ? A ASP 132 OD1 ? ? ? 1_555 D MG . MG ? ? A ASP 132 A MG 502 1_555 ? ? ? ? ? ? ? 2.720 ? ? 
metalc6  metalc ? ? A ASP 132 OD1 ? ? ? 1_555 E MG . MG ? ? A ASP 132 A MG 503 1_555 ? ? ? ? ? ? ? 2.682 ? ? 
metalc7  metalc ? ? A ASP 132 OD2 ? ? ? 1_555 E MG . MG ? ? A ASP 132 A MG 503 1_555 ? ? ? ? ? ? ? 2.275 ? ? 
metalc8  metalc ? ? A ASP 136 OD2 ? ? ? 1_555 D MG . MG ? ? A ASP 136 A MG 502 1_555 ? ? ? ? ? ? ? 2.410 ? ? 
metalc9  metalc ? ? C POV .   O11 ? ? ? 1_555 D MG . MG ? ? A POV 501 A MG 502 1_555 ? ? ? ? ? ? ? 2.761 ? ? 
metalc10 metalc ? ? C POV .   O12 ? ? ? 1_555 D MG . MG ? ? A POV 501 A MG 502 1_555 ? ? ? ? ? ? ? 2.908 ? ? 
metalc11 metalc ? ? C POV .   O13 ? ? ? 1_555 D MG . MG ? ? A POV 501 A MG 502 1_555 ? ? ? ? ? ? ? 2.007 ? ? 
metalc12 metalc ? ? B ASP 111 OD1 ? ? ? 1_555 G MG . MG ? ? B ASP 111 B MG 502 1_555 ? ? ? ? ? ? ? 2.651 ? ? 
metalc13 metalc ? ? B ASP 111 OD2 ? ? ? 1_555 G MG . MG ? ? B ASP 111 B MG 502 1_555 ? ? ? ? ? ? ? 2.413 ? ? 
metalc14 metalc ? ? B ASP 114 OD1 ? ? ? 1_555 H MG . MG ? ? B ASP 114 B MG 503 1_555 ? ? ? ? ? ? ? 2.075 ? ? 
metalc15 metalc ? ? B ASP 114 OD2 ? ? ? 1_555 H MG . MG ? ? B ASP 114 B MG 503 1_555 ? ? ? ? ? ? ? 2.569 ? ? 
metalc16 metalc ? ? B ASP 132 OD1 ? ? ? 1_555 G MG . MG ? ? B ASP 132 B MG 502 1_555 ? ? ? ? ? ? ? 2.720 ? ? 
metalc17 metalc ? ? B ASP 132 OD1 ? ? ? 1_555 H MG . MG ? ? B ASP 132 B MG 503 1_555 ? ? ? ? ? ? ? 2.682 ? ? 
metalc18 metalc ? ? B ASP 132 OD2 ? ? ? 1_555 H MG . MG ? ? B ASP 132 B MG 503 1_555 ? ? ? ? ? ? ? 2.275 ? ? 
metalc19 metalc ? ? B ASP 136 OD2 ? ? ? 1_555 G MG . MG ? ? B ASP 136 B MG 502 1_555 ? ? ? ? ? ? ? 2.410 ? ? 
metalc20 metalc ? ? F POV .   O11 ? ? ? 1_555 G MG . MG ? ? B POV 501 B MG 502 1_555 ? ? ? ? ? ? ? 2.761 ? ? 
metalc21 metalc ? ? F POV .   O12 ? ? ? 1_555 G MG . MG ? ? B POV 501 B MG 502 1_555 ? ? ? ? ? ? ? 2.908 ? ? 
metalc22 metalc ? ? F POV .   O13 ? ? ? 1_555 G MG . MG ? ? B POV 501 B MG 502 1_555 ? ? ? ? ? ? ? 2.007 ? ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD2 ? A ASP 111 ? A ASP 111 ? 1_555 51.0  ? 
2  OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 61.6  ? 
3  OD2 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 76.3  ? 
4  OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 115.5 ? 
5  OD2 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 88.2  ? 
6  OD1 ? A ASP 132 ? A ASP 132 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 61.6  ? 
7  OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O11 ? C POV .   ? A POV 501 ? 1_555 142.5 ? 
8  OD2 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O11 ? C POV .   ? A POV 501 ? 1_555 93.2  ? 
9  OD1 ? A ASP 132 ? A ASP 132 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O11 ? C POV .   ? A POV 501 ? 1_555 127.6 ? 
10 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O11 ? C POV .   ? A POV 501 ? 1_555 67.0  ? 
11 OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O12 ? C POV .   ? A POV 501 ? 1_555 105.4 ? 
12 OD2 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O12 ? C POV .   ? A POV 501 ? 1_555 89.1  ? 
13 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O12 ? C POV .   ? A POV 501 ? 1_555 164.7 ? 
14 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O12 ? C POV .   ? A POV 501 ? 1_555 123.7 ? 
15 O11 ? C POV .   ? A POV 501 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O12 ? C POV .   ? A POV 501 ? 1_555 57.0  ? 
16 OD1 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 141.0 ? 
17 OD2 ? A ASP 111 ? A ASP 111 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 147.8 ? 
18 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 135.2 ? 
19 OD2 ? A ASP 136 ? A ASP 136 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 101.2 ? 
20 O11 ? C POV .   ? A POV 501 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 63.5  ? 
21 O12 ? C POV .   ? A POV 501 ? 1_555 MG ? D MG . ? A MG 502 ? 1_555 O13 ? C POV .   ? A POV 501 ? 1_555 60.0  ? 
22 OD1 ? A ASP 114 ? A ASP 114 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD2 ? A ASP 114 ? A ASP 114 ? 1_555 53.5  ? 
23 OD1 ? A ASP 114 ? A ASP 114 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 150.5 ? 
24 OD2 ? A ASP 114 ? A ASP 114 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 101.1 ? 
25 OD1 ? A ASP 114 ? A ASP 114 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD2 ? A ASP 132 ? A ASP 132 ? 1_555 142.6 ? 
26 OD2 ? A ASP 114 ? A ASP 114 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD2 ? A ASP 132 ? A ASP 132 ? 1_555 146.3 ? 
27 OD1 ? A ASP 132 ? A ASP 132 ? 1_555 MG ? E MG . ? A MG 503 ? 1_555 OD2 ? A ASP 132 ? A ASP 132 ? 1_555 51.2  ? 
28 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 51.0  ? 
29 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 61.6  ? 
30 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 76.3  ? 
31 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 115.6 ? 
32 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 88.2  ? 
33 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 61.6  ? 
34 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O11 ? F POV .   ? B POV 501 ? 1_555 142.5 ? 
35 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O11 ? F POV .   ? B POV 501 ? 1_555 93.2  ? 
36 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O11 ? F POV .   ? B POV 501 ? 1_555 127.6 ? 
37 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O11 ? F POV .   ? B POV 501 ? 1_555 67.0  ? 
38 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O12 ? F POV .   ? B POV 501 ? 1_555 105.4 ? 
39 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O12 ? F POV .   ? B POV 501 ? 1_555 89.1  ? 
40 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O12 ? F POV .   ? B POV 501 ? 1_555 164.7 ? 
41 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O12 ? F POV .   ? B POV 501 ? 1_555 123.7 ? 
42 O11 ? F POV .   ? B POV 501 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O12 ? F POV .   ? B POV 501 ? 1_555 57.0  ? 
43 OD1 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 141.0 ? 
44 OD2 ? B ASP 111 ? B ASP 111 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 147.8 ? 
45 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 135.2 ? 
46 OD2 ? B ASP 136 ? B ASP 136 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 101.2 ? 
47 O11 ? F POV .   ? B POV 501 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 63.5  ? 
48 O12 ? F POV .   ? B POV 501 ? 1_555 MG ? G MG . ? B MG 502 ? 1_555 O13 ? F POV .   ? B POV 501 ? 1_555 60.0  ? 
49 OD1 ? B ASP 114 ? B ASP 114 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD2 ? B ASP 114 ? B ASP 114 ? 1_555 53.5  ? 
50 OD1 ? B ASP 114 ? B ASP 114 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 150.5 ? 
51 OD2 ? B ASP 114 ? B ASP 114 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 101.1 ? 
52 OD1 ? B ASP 114 ? B ASP 114 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD2 ? B ASP 132 ? B ASP 132 ? 1_555 142.6 ? 
53 OD2 ? B ASP 114 ? B ASP 114 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD2 ? B ASP 132 ? B ASP 132 ? 1_555 146.3 ? 
54 OD1 ? B ASP 132 ? B ASP 132 ? 1_555 MG ? H MG . ? B MG 503 ? 1_555 OD2 ? B ASP 132 ? B ASP 132 ? 1_555 51.2  ? 
# 
_pdbx_entry_details.entry_id                   9UET 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1 A ASP 111 ? ? MG  A MG  503 ? ? 1.50 
2  1 OD1 B ASP 111 ? ? MG  B MG  503 ? ? 1.50 
3  1 OG1 B THR 67  ? ? CE2 B PHE 131 ? ? 1.54 
4  1 OG1 A THR 67  ? ? CE2 A PHE 131 ? ? 1.54 
5  1 OD2 B ASP 132 ? ? MG  B MG  502 ? ? 1.67 
6  1 OD2 A ASP 132 ? ? MG  A MG  502 ? ? 1.67 
7  1 OG1 A THR 67  ? ? CZ  A PHE 131 ? ? 1.80 
8  1 OG1 B THR 67  ? ? CZ  B PHE 131 ? ? 1.80 
9  1 CD2 A LEU 59  ? ? NH1 A ARG 120 ? ? 1.91 
10 1 CD2 B LEU 59  ? ? NH1 B ARG 120 ? ? 1.91 
11 1 O   A ALA 118 ? ? OG  A SER 123 ? ? 1.97 
12 1 O   B ALA 118 ? ? OG  B SER 123 ? ? 1.97 
13 1 CB  A THR 67  ? ? CE2 A PHE 131 ? ? 2.13 
14 1 CB  B THR 67  ? ? CE2 B PHE 131 ? ? 2.13 
15 1 O   A TYR 179 ? ? OG1 A THR 258 ? ? 2.18 
16 1 O   B TYR 179 ? ? OG1 B THR 258 ? ? 2.18 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 CB A ASP 114 ? ? CG A ASP 114 ? ? OD1 A ASP 114 ? ? 124.01 118.30 5.71   0.90 N 
2  1 CB A GLN 117 ? ? CA A GLN 117 ? ? C   A GLN 117 ? ? 86.26  110.40 -24.14 2.00 N 
3  1 CB A ALA 118 ? ? CA A ALA 118 ? ? C   A ALA 118 ? ? 100.89 110.10 -9.21  1.50 N 
4  1 N  A THR 121 ? ? CA A THR 121 ? ? CB  A THR 121 ? ? 123.53 110.30 13.23  1.90 N 
5  1 N  A THR 121 ? ? CA A THR 121 ? ? C   A THR 121 ? ? 90.30  111.00 -20.70 2.70 N 
6  1 N  A PRO 126 ? ? CA A PRO 126 ? ? CB  A PRO 126 ? ? 95.00  103.30 -8.30  1.20 N 
7  1 N  A PRO 126 ? ? CD A PRO 126 ? ? CG  A PRO 126 ? ? 89.59  103.20 -13.61 1.50 N 
8  1 N  A HIS 133 ? ? CA A HIS 133 ? ? CB  A HIS 133 ? ? 99.73  110.60 -10.87 1.80 N 
9  1 CB A ASN 343 ? ? CA A ASN 343 ? ? C   A ASN 343 ? ? 124.11 110.40 13.71  2.00 N 
10 1 N  A ASN 343 ? ? CA A ASN 343 ? ? C   A ASN 343 ? ? 89.88  111.00 -21.12 2.70 N 
11 1 CB B ASP 114 ? ? CG B ASP 114 ? ? OD1 B ASP 114 ? ? 124.02 118.30 5.72   0.90 N 
12 1 CB B GLN 117 ? ? CA B GLN 117 ? ? C   B GLN 117 ? ? 86.27  110.40 -24.13 2.00 N 
13 1 CB B ALA 118 ? ? CA B ALA 118 ? ? C   B ALA 118 ? ? 100.85 110.10 -9.25  1.50 N 
14 1 N  B THR 121 ? ? CA B THR 121 ? ? CB  B THR 121 ? ? 123.53 110.30 13.23  1.90 N 
15 1 N  B THR 121 ? ? CA B THR 121 ? ? C   B THR 121 ? ? 90.30  111.00 -20.70 2.70 N 
16 1 N  B PRO 126 ? ? CA B PRO 126 ? ? CB  B PRO 126 ? ? 95.00  103.30 -8.30  1.20 N 
17 1 N  B PRO 126 ? ? CD B PRO 126 ? ? CG  B PRO 126 ? ? 89.62  103.20 -13.58 1.50 N 
18 1 N  B HIS 133 ? ? CA B HIS 133 ? ? CB  B HIS 133 ? ? 99.73  110.60 -10.87 1.80 N 
19 1 CB B ASN 343 ? ? CA B ASN 343 ? ? C   B ASN 343 ? ? 124.09 110.40 13.69  2.00 N 
20 1 N  B ASN 343 ? ? CA B ASN 343 ? ? C   B ASN 343 ? ? 89.91  111.00 -21.09 2.70 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLU A 129 ? ? -111.15 -156.66 
2  1 LEU A 130 ? ? 42.76   25.80   
3  1 PHE A 131 ? ? -149.99 -71.49  
4  1 ASP A 190 ? ? -153.79 -157.88 
5  1 LEU A 224 ? ? 75.76   -9.74   
6  1 HIS A 293 ? ? -156.93 82.19   
7  1 CYS A 295 ? ? 66.71   -7.55   
8  1 GLU B 129 ? ? -111.15 -156.66 
9  1 LEU B 130 ? ? 42.74   25.81   
10 1 PHE B 131 ? ? -150.00 -71.45  
11 1 ASP B 190 ? ? -153.78 -157.85 
12 1 LEU B 224 ? ? 75.81   -9.74   
13 1 HIS B 293 ? ? -156.91 82.19   
14 1 CYS B 295 ? ? 66.70   -7.50   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9UET 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9UET 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.68 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               295158 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Choline-phosphotransferase 1' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9UET 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1500 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
_em_imaging.objective_aperture              ? 
_em_imaging.microscope_serial_number        ? 
_em_imaging.microscope_version              ? 
# 
_em_vitrification.entry_id              9UET 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              100 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   281 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9UET 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A ALA 3   ? A ALA 3   
4  1 Y 1 A GLY 4   ? A GLY 4   
5  1 Y 1 A ALA 5   ? A ALA 5   
6  1 Y 1 A GLY 6   ? A GLY 6   
7  1 Y 1 A ALA 7   ? A ALA 7   
8  1 Y 1 A GLY 8   ? A GLY 8   
9  1 Y 1 A SER 9   ? A SER 9   
10 1 Y 1 A ALA 10  ? A ALA 10  
11 1 Y 1 A PRO 11  ? A PRO 11  
12 1 Y 1 A ARG 12  ? A ARG 12  
13 1 Y 1 A TRP 13  ? A TRP 13  
14 1 Y 1 A LEU 14  ? A LEU 14  
15 1 Y 1 A ARG 15  ? A ARG 15  
16 1 Y 1 A THR 384 ? A THR 384 
17 1 Y 1 A ALA 385 ? A ALA 385 
18 1 Y 1 A CYS 386 ? A CYS 386 
19 1 Y 1 A HIS 387 ? A HIS 387 
20 1 Y 1 A GLN 388 ? A GLN 388 
21 1 Y 1 A ALA 389 ? A ALA 389 
22 1 Y 1 A PRO 390 ? A PRO 390 
23 1 Y 1 A GLU 391 ? A GLU 391 
24 1 Y 1 A GLN 392 ? A GLN 392 
25 1 Y 1 A VAL 393 ? A VAL 393 
26 1 Y 1 A GLN 394 ? A GLN 394 
27 1 Y 1 A VAL 395 ? A VAL 395 
28 1 Y 1 A LEU 396 ? A LEU 396 
29 1 Y 1 A SER 397 ? A SER 397 
30 1 Y 1 A SER 398 ? A SER 398 
31 1 Y 1 A LYS 399 ? A LYS 399 
32 1 Y 1 A SER 400 ? A SER 400 
33 1 Y 1 A HIS 401 ? A HIS 401 
34 1 Y 1 A GLN 402 ? A GLN 402 
35 1 Y 1 A ASN 403 ? A ASN 403 
36 1 Y 1 A ASN 404 ? A ASN 404 
37 1 Y 1 A MET 405 ? A MET 405 
38 1 Y 1 A ASP 406 ? A ASP 406 
39 1 Y 1 B MET 1   ? B MET 1   
40 1 Y 1 B ALA 2   ? B ALA 2   
41 1 Y 1 B ALA 3   ? B ALA 3   
42 1 Y 1 B GLY 4   ? B GLY 4   
43 1 Y 1 B ALA 5   ? B ALA 5   
44 1 Y 1 B GLY 6   ? B GLY 6   
45 1 Y 1 B ALA 7   ? B ALA 7   
46 1 Y 1 B GLY 8   ? B GLY 8   
47 1 Y 1 B SER 9   ? B SER 9   
48 1 Y 1 B ALA 10  ? B ALA 10  
49 1 Y 1 B PRO 11  ? B PRO 11  
50 1 Y 1 B ARG 12  ? B ARG 12  
51 1 Y 1 B TRP 13  ? B TRP 13  
52 1 Y 1 B LEU 14  ? B LEU 14  
53 1 Y 1 B ARG 15  ? B ARG 15  
54 1 Y 1 B THR 384 ? B THR 384 
55 1 Y 1 B ALA 385 ? B ALA 385 
56 1 Y 1 B CYS 386 ? B CYS 386 
57 1 Y 1 B HIS 387 ? B HIS 387 
58 1 Y 1 B GLN 388 ? B GLN 388 
59 1 Y 1 B ALA 389 ? B ALA 389 
60 1 Y 1 B PRO 390 ? B PRO 390 
61 1 Y 1 B GLU 391 ? B GLU 391 
62 1 Y 1 B GLN 392 ? B GLN 392 
63 1 Y 1 B VAL 393 ? B VAL 393 
64 1 Y 1 B GLN 394 ? B GLN 394 
65 1 Y 1 B VAL 395 ? B VAL 395 
66 1 Y 1 B LEU 396 ? B LEU 396 
67 1 Y 1 B SER 397 ? B SER 397 
68 1 Y 1 B SER 398 ? B SER 398 
69 1 Y 1 B LYS 399 ? B LYS 399 
70 1 Y 1 B SER 400 ? B SER 400 
71 1 Y 1 B HIS 401 ? B HIS 401 
72 1 Y 1 B GLN 402 ? B GLN 402 
73 1 Y 1 B ASN 403 ? B ASN 403 
74 1 Y 1 B ASN 404 ? B ASN 404 
75 1 Y 1 B MET 405 ? B MET 405 
76 1 Y 1 B ASP 406 ? B ASP 406 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HIS N    N  N N 137 
HIS CA   C  N S 138 
HIS C    C  N N 139 
HIS O    O  N N 140 
HIS CB   C  N N 141 
HIS CG   C  Y N 142 
HIS ND1  N  Y N 143 
HIS CD2  C  Y N 144 
HIS CE1  C  Y N 145 
HIS NE2  N  Y N 146 
HIS OXT  O  N N 147 
HIS H    H  N N 148 
HIS H2   H  N N 149 
HIS HA   H  N N 150 
HIS HB2  H  N N 151 
HIS HB3  H  N N 152 
HIS HD1  H  N N 153 
HIS HD2  H  N N 154 
HIS HE1  H  N N 155 
HIS HE2  H  N N 156 
HIS HXT  H  N N 157 
ILE N    N  N N 158 
ILE CA   C  N S 159 
ILE C    C  N N 160 
ILE O    O  N N 161 
ILE CB   C  N S 162 
ILE CG1  C  N N 163 
ILE CG2  C  N N 164 
ILE CD1  C  N N 165 
ILE OXT  O  N N 166 
ILE H    H  N N 167 
ILE H2   H  N N 168 
ILE HA   H  N N 169 
ILE HB   H  N N 170 
ILE HG12 H  N N 171 
ILE HG13 H  N N 172 
ILE HG21 H  N N 173 
ILE HG22 H  N N 174 
ILE HG23 H  N N 175 
ILE HD11 H  N N 176 
ILE HD12 H  N N 177 
ILE HD13 H  N N 178 
ILE HXT  H  N N 179 
LEU N    N  N N 180 
LEU CA   C  N S 181 
LEU C    C  N N 182 
LEU O    O  N N 183 
LEU CB   C  N N 184 
LEU CG   C  N N 185 
LEU CD1  C  N N 186 
LEU CD2  C  N N 187 
LEU OXT  O  N N 188 
LEU H    H  N N 189 
LEU H2   H  N N 190 
LEU HA   H  N N 191 
LEU HB2  H  N N 192 
LEU HB3  H  N N 193 
LEU HG   H  N N 194 
LEU HD11 H  N N 195 
LEU HD12 H  N N 196 
LEU HD13 H  N N 197 
LEU HD21 H  N N 198 
LEU HD22 H  N N 199 
LEU HD23 H  N N 200 
LEU HXT  H  N N 201 
LYS N    N  N N 202 
LYS CA   C  N S 203 
LYS C    C  N N 204 
LYS O    O  N N 205 
LYS CB   C  N N 206 
LYS CG   C  N N 207 
LYS CD   C  N N 208 
LYS CE   C  N N 209 
LYS NZ   N  N N 210 
LYS OXT  O  N N 211 
LYS H    H  N N 212 
LYS H2   H  N N 213 
LYS HA   H  N N 214 
LYS HB2  H  N N 215 
LYS HB3  H  N N 216 
LYS HG2  H  N N 217 
LYS HG3  H  N N 218 
LYS HD2  H  N N 219 
LYS HD3  H  N N 220 
LYS HE2  H  N N 221 
LYS HE3  H  N N 222 
LYS HZ1  H  N N 223 
LYS HZ2  H  N N 224 
LYS HZ3  H  N N 225 
LYS HXT  H  N N 226 
MET N    N  N N 227 
MET CA   C  N S 228 
MET C    C  N N 229 
MET O    O  N N 230 
MET CB   C  N N 231 
MET CG   C  N N 232 
MET SD   S  N N 233 
MET CE   C  N N 234 
MET OXT  O  N N 235 
MET H    H  N N 236 
MET H2   H  N N 237 
MET HA   H  N N 238 
MET HB2  H  N N 239 
MET HB3  H  N N 240 
MET HG2  H  N N 241 
MET HG3  H  N N 242 
MET HE1  H  N N 243 
MET HE2  H  N N 244 
MET HE3  H  N N 245 
MET HXT  H  N N 246 
MG  MG   MG N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
POV N    N  N N 271 
POV P    P  N N 272 
POV C1   C  N N 273 
POV C2   C  N S 274 
POV C3   C  N N 275 
POV C210 C  N N 276 
POV C310 C  N N 277 
POV C11  C  N N 278 
POV O11  O  N N 279 
POV C211 C  N N 280 
POV C311 C  N N 281 
POV C12  C  N N 282 
POV O12  O  N N 283 
POV C212 C  N N 284 
POV C312 C  N N 285 
POV C13  C  N N 286 
POV O13  O  N N 287 
POV C213 C  N N 288 
POV C313 C  N N 289 
POV C14  C  N N 290 
POV O14  O  N N 291 
POV C214 C  N N 292 
POV C314 C  N N 293 
POV C15  C  N N 294 
POV C215 C  N N 295 
POV C315 C  N N 296 
POV C216 C  N N 297 
POV C316 C  N N 298 
POV C217 C  N N 299 
POV C218 C  N N 300 
POV C21  C  N N 301 
POV O21  O  N N 302 
POV C22  C  N N 303 
POV O22  O  N N 304 
POV C23  C  N N 305 
POV C24  C  N N 306 
POV C25  C  N N 307 
POV C26  C  N N 308 
POV C27  C  N N 309 
POV C28  C  N N 310 
POV C29  C  N N 311 
POV C31  C  N N 312 
POV O31  O  N N 313 
POV C32  C  N N 314 
POV O32  O  N N 315 
POV C33  C  N N 316 
POV C34  C  N N 317 
POV C35  C  N N 318 
POV C36  C  N N 319 
POV C37  C  N N 320 
POV C38  C  N N 321 
POV C39  C  N N 322 
POV H29  H  N N 323 
POV H1   H  N N 324 
POV H1A  H  N N 325 
POV H2   H  N N 326 
POV H3   H  N N 327 
POV H3A  H  N N 328 
POV H310 H  N N 329 
POV H31A H  N N 330 
POV H210 H  N N 331 
POV H11  H  N N 332 
POV H11A H  N N 333 
POV H211 H  N N 334 
POV H21A H  N N 335 
POV H311 H  N N 336 
POV H31B H  N N 337 
POV H12  H  N N 338 
POV H12A H  N N 339 
POV H22  H  N N 340 
POV H212 H  N N 341 
POV H22A H  N N 342 
POV H21B H  N N 343 
POV H32  H  N N 344 
POV H312 H  N N 345 
POV H32A H  N N 346 
POV H31C H  N N 347 
POV H13  H  N N 348 
POV H13A H  N N 349 
POV H13B H  N N 350 
POV H23  H  N N 351 
POV H213 H  N N 352 
POV H23A H  N N 353 
POV H21C H  N N 354 
POV H33  H  N N 355 
POV H313 H  N N 356 
POV H33A H  N N 357 
POV H31D H  N N 358 
POV H14  H  N N 359 
POV H14A H  N N 360 
POV H14B H  N N 361 
POV H24  H  N N 362 
POV H214 H  N N 363 
POV H24A H  N N 364 
POV H21D H  N N 365 
POV H34  H  N N 366 
POV H314 H  N N 367 
POV H34A H  N N 368 
POV H31E H  N N 369 
POV H15  H  N N 370 
POV H15A H  N N 371 
POV H15B H  N N 372 
POV H25  H  N N 373 
POV H215 H  N N 374 
POV H25A H  N N 375 
POV H21E H  N N 376 
POV H35  H  N N 377 
POV H315 H  N N 378 
POV H35A H  N N 379 
POV H31F H  N N 380 
POV H26  H  N N 381 
POV H216 H  N N 382 
POV H26A H  N N 383 
POV H21F H  N N 384 
POV H36  H  N N 385 
POV H316 H  N N 386 
POV H36A H  N N 387 
POV H31G H  N N 388 
POV H31H H  N N 389 
POV H27  H  N N 390 
POV H217 H  N N 391 
POV H27A H  N N 392 
POV H21G H  N N 393 
POV H37  H  N N 394 
POV H37A H  N N 395 
POV H28  H  N N 396 
POV H218 H  N N 397 
POV H28A H  N N 398 
POV H21H H  N N 399 
POV H21J H  N N 400 
POV H38  H  N N 401 
POV H38A H  N N 402 
POV H39  H  N N 403 
POV H39A H  N N 404 
PRO N    N  N N 405 
PRO CA   C  N S 406 
PRO C    C  N N 407 
PRO O    O  N N 408 
PRO CB   C  N N 409 
PRO CG   C  N N 410 
PRO CD   C  N N 411 
PRO OXT  O  N N 412 
PRO H    H  N N 413 
PRO HA   H  N N 414 
PRO HB2  H  N N 415 
PRO HB3  H  N N 416 
PRO HG2  H  N N 417 
PRO HG3  H  N N 418 
PRO HD2  H  N N 419 
PRO HD3  H  N N 420 
PRO HXT  H  N N 421 
SER N    N  N N 422 
SER CA   C  N S 423 
SER C    C  N N 424 
SER O    O  N N 425 
SER CB   C  N N 426 
SER OG   O  N N 427 
SER OXT  O  N N 428 
SER H    H  N N 429 
SER H2   H  N N 430 
SER HA   H  N N 431 
SER HB2  H  N N 432 
SER HB3  H  N N 433 
SER HG   H  N N 434 
SER HXT  H  N N 435 
THR N    N  N N 436 
THR CA   C  N S 437 
THR C    C  N N 438 
THR O    O  N N 439 
THR CB   C  N R 440 
THR OG1  O  N N 441 
THR CG2  C  N N 442 
THR OXT  O  N N 443 
THR H    H  N N 444 
THR H2   H  N N 445 
THR HA   H  N N 446 
THR HB   H  N N 447 
THR HG1  H  N N 448 
THR HG21 H  N N 449 
THR HG22 H  N N 450 
THR HG23 H  N N 451 
THR HXT  H  N N 452 
TRP N    N  N N 453 
TRP CA   C  N S 454 
TRP C    C  N N 455 
TRP O    O  N N 456 
TRP CB   C  N N 457 
TRP CG   C  Y N 458 
TRP CD1  C  Y N 459 
TRP CD2  C  Y N 460 
TRP NE1  N  Y N 461 
TRP CE2  C  Y N 462 
TRP CE3  C  Y N 463 
TRP CZ2  C  Y N 464 
TRP CZ3  C  Y N 465 
TRP CH2  C  Y N 466 
TRP OXT  O  N N 467 
TRP H    H  N N 468 
TRP H2   H  N N 469 
TRP HA   H  N N 470 
TRP HB2  H  N N 471 
TRP HB3  H  N N 472 
TRP HD1  H  N N 473 
TRP HE1  H  N N 474 
TRP HE3  H  N N 475 
TRP HZ2  H  N N 476 
TRP HZ3  H  N N 477 
TRP HH2  H  N N 478 
TRP HXT  H  N N 479 
TYR N    N  N N 480 
TYR CA   C  N S 481 
TYR C    C  N N 482 
TYR O    O  N N 483 
TYR CB   C  N N 484 
TYR CG   C  Y N 485 
TYR CD1  C  Y N 486 
TYR CD2  C  Y N 487 
TYR CE1  C  Y N 488 
TYR CE2  C  Y N 489 
TYR CZ   C  Y N 490 
TYR OH   O  N N 491 
TYR OXT  O  N N 492 
TYR H    H  N N 493 
TYR H2   H  N N 494 
TYR HA   H  N N 495 
TYR HB2  H  N N 496 
TYR HB3  H  N N 497 
TYR HD1  H  N N 498 
TYR HD2  H  N N 499 
TYR HE1  H  N N 500 
TYR HE2  H  N N 501 
TYR HH   H  N N 502 
TYR HXT  H  N N 503 
VAL N    N  N N 504 
VAL CA   C  N S 505 
VAL C    C  N N 506 
VAL O    O  N N 507 
VAL CB   C  N N 508 
VAL CG1  C  N N 509 
VAL CG2  C  N N 510 
VAL OXT  O  N N 511 
VAL H    H  N N 512 
VAL H2   H  N N 513 
VAL HA   H  N N 514 
VAL HB   H  N N 515 
VAL HG11 H  N N 516 
VAL HG12 H  N N 517 
VAL HG13 H  N N 518 
VAL HG21 H  N N 519 
VAL HG22 H  N N 520 
VAL HG23 H  N N 521 
VAL HXT  H  N N 522 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N    CA   sing N N 1   
ALA N    H    sing N N 2   
ALA N    H2   sing N N 3   
ALA CA   C    sing N N 4   
ALA CA   CB   sing N N 5   
ALA CA   HA   sing N N 6   
ALA C    O    doub N N 7   
ALA C    OXT  sing N N 8   
ALA CB   HB1  sing N N 9   
ALA CB   HB2  sing N N 10  
ALA CB   HB3  sing N N 11  
ALA OXT  HXT  sing N N 12  
ARG N    CA   sing N N 13  
ARG N    H    sing N N 14  
ARG N    H2   sing N N 15  
ARG CA   C    sing N N 16  
ARG CA   CB   sing N N 17  
ARG CA   HA   sing N N 18  
ARG C    O    doub N N 19  
ARG C    OXT  sing N N 20  
ARG CB   CG   sing N N 21  
ARG CB   HB2  sing N N 22  
ARG CB   HB3  sing N N 23  
ARG CG   CD   sing N N 24  
ARG CG   HG2  sing N N 25  
ARG CG   HG3  sing N N 26  
ARG CD   NE   sing N N 27  
ARG CD   HD2  sing N N 28  
ARG CD   HD3  sing N N 29  
ARG NE   CZ   sing N N 30  
ARG NE   HE   sing N N 31  
ARG CZ   NH1  sing N N 32  
ARG CZ   NH2  doub N N 33  
ARG NH1  HH11 sing N N 34  
ARG NH1  HH12 sing N N 35  
ARG NH2  HH21 sing N N 36  
ARG NH2  HH22 sing N N 37  
ARG OXT  HXT  sing N N 38  
ASN N    CA   sing N N 39  
ASN N    H    sing N N 40  
ASN N    H2   sing N N 41  
ASN CA   C    sing N N 42  
ASN CA   CB   sing N N 43  
ASN CA   HA   sing N N 44  
ASN C    O    doub N N 45  
ASN C    OXT  sing N N 46  
ASN CB   CG   sing N N 47  
ASN CB   HB2  sing N N 48  
ASN CB   HB3  sing N N 49  
ASN CG   OD1  doub N N 50  
ASN CG   ND2  sing N N 51  
ASN ND2  HD21 sing N N 52  
ASN ND2  HD22 sing N N 53  
ASN OXT  HXT  sing N N 54  
ASP N    CA   sing N N 55  
ASP N    H    sing N N 56  
ASP N    H2   sing N N 57  
ASP CA   C    sing N N 58  
ASP CA   CB   sing N N 59  
ASP CA   HA   sing N N 60  
ASP C    O    doub N N 61  
ASP C    OXT  sing N N 62  
ASP CB   CG   sing N N 63  
ASP CB   HB2  sing N N 64  
ASP CB   HB3  sing N N 65  
ASP CG   OD1  doub N N 66  
ASP CG   OD2  sing N N 67  
ASP OD2  HD2  sing N N 68  
ASP OXT  HXT  sing N N 69  
CYS N    CA   sing N N 70  
CYS N    H    sing N N 71  
CYS N    H2   sing N N 72  
CYS CA   C    sing N N 73  
CYS CA   CB   sing N N 74  
CYS CA   HA   sing N N 75  
CYS C    O    doub N N 76  
CYS C    OXT  sing N N 77  
CYS CB   SG   sing N N 78  
CYS CB   HB2  sing N N 79  
CYS CB   HB3  sing N N 80  
CYS SG   HG   sing N N 81  
CYS OXT  HXT  sing N N 82  
GLN N    CA   sing N N 83  
GLN N    H    sing N N 84  
GLN N    H2   sing N N 85  
GLN CA   C    sing N N 86  
GLN CA   CB   sing N N 87  
GLN CA   HA   sing N N 88  
GLN C    O    doub N N 89  
GLN C    OXT  sing N N 90  
GLN CB   CG   sing N N 91  
GLN CB   HB2  sing N N 92  
GLN CB   HB3  sing N N 93  
GLN CG   CD   sing N N 94  
GLN CG   HG2  sing N N 95  
GLN CG   HG3  sing N N 96  
GLN CD   OE1  doub N N 97  
GLN CD   NE2  sing N N 98  
GLN NE2  HE21 sing N N 99  
GLN NE2  HE22 sing N N 100 
GLN OXT  HXT  sing N N 101 
GLU N    CA   sing N N 102 
GLU N    H    sing N N 103 
GLU N    H2   sing N N 104 
GLU CA   C    sing N N 105 
GLU CA   CB   sing N N 106 
GLU CA   HA   sing N N 107 
GLU C    O    doub N N 108 
GLU C    OXT  sing N N 109 
GLU CB   CG   sing N N 110 
GLU CB   HB2  sing N N 111 
GLU CB   HB3  sing N N 112 
GLU CG   CD   sing N N 113 
GLU CG   HG2  sing N N 114 
GLU CG   HG3  sing N N 115 
GLU CD   OE1  doub N N 116 
GLU CD   OE2  sing N N 117 
GLU OE2  HE2  sing N N 118 
GLU OXT  HXT  sing N N 119 
GLY N    CA   sing N N 120 
GLY N    H    sing N N 121 
GLY N    H2   sing N N 122 
GLY CA   C    sing N N 123 
GLY CA   HA2  sing N N 124 
GLY CA   HA3  sing N N 125 
GLY C    O    doub N N 126 
GLY C    OXT  sing N N 127 
GLY OXT  HXT  sing N N 128 
HIS N    CA   sing N N 129 
HIS N    H    sing N N 130 
HIS N    H2   sing N N 131 
HIS CA   C    sing N N 132 
HIS CA   CB   sing N N 133 
HIS CA   HA   sing N N 134 
HIS C    O    doub N N 135 
HIS C    OXT  sing N N 136 
HIS CB   CG   sing N N 137 
HIS CB   HB2  sing N N 138 
HIS CB   HB3  sing N N 139 
HIS CG   ND1  sing Y N 140 
HIS CG   CD2  doub Y N 141 
HIS ND1  CE1  doub Y N 142 
HIS ND1  HD1  sing N N 143 
HIS CD2  NE2  sing Y N 144 
HIS CD2  HD2  sing N N 145 
HIS CE1  NE2  sing Y N 146 
HIS CE1  HE1  sing N N 147 
HIS NE2  HE2  sing N N 148 
HIS OXT  HXT  sing N N 149 
ILE N    CA   sing N N 150 
ILE N    H    sing N N 151 
ILE N    H2   sing N N 152 
ILE CA   C    sing N N 153 
ILE CA   CB   sing N N 154 
ILE CA   HA   sing N N 155 
ILE C    O    doub N N 156 
ILE C    OXT  sing N N 157 
ILE CB   CG1  sing N N 158 
ILE CB   CG2  sing N N 159 
ILE CB   HB   sing N N 160 
ILE CG1  CD1  sing N N 161 
ILE CG1  HG12 sing N N 162 
ILE CG1  HG13 sing N N 163 
ILE CG2  HG21 sing N N 164 
ILE CG2  HG22 sing N N 165 
ILE CG2  HG23 sing N N 166 
ILE CD1  HD11 sing N N 167 
ILE CD1  HD12 sing N N 168 
ILE CD1  HD13 sing N N 169 
ILE OXT  HXT  sing N N 170 
LEU N    CA   sing N N 171 
LEU N    H    sing N N 172 
LEU N    H2   sing N N 173 
LEU CA   C    sing N N 174 
LEU CA   CB   sing N N 175 
LEU CA   HA   sing N N 176 
LEU C    O    doub N N 177 
LEU C    OXT  sing N N 178 
LEU CB   CG   sing N N 179 
LEU CB   HB2  sing N N 180 
LEU CB   HB3  sing N N 181 
LEU CG   CD1  sing N N 182 
LEU CG   CD2  sing N N 183 
LEU CG   HG   sing N N 184 
LEU CD1  HD11 sing N N 185 
LEU CD1  HD12 sing N N 186 
LEU CD1  HD13 sing N N 187 
LEU CD2  HD21 sing N N 188 
LEU CD2  HD22 sing N N 189 
LEU CD2  HD23 sing N N 190 
LEU OXT  HXT  sing N N 191 
LYS N    CA   sing N N 192 
LYS N    H    sing N N 193 
LYS N    H2   sing N N 194 
LYS CA   C    sing N N 195 
LYS CA   CB   sing N N 196 
LYS CA   HA   sing N N 197 
LYS C    O    doub N N 198 
LYS C    OXT  sing N N 199 
LYS CB   CG   sing N N 200 
LYS CB   HB2  sing N N 201 
LYS CB   HB3  sing N N 202 
LYS CG   CD   sing N N 203 
LYS CG   HG2  sing N N 204 
LYS CG   HG3  sing N N 205 
LYS CD   CE   sing N N 206 
LYS CD   HD2  sing N N 207 
LYS CD   HD3  sing N N 208 
LYS CE   NZ   sing N N 209 
LYS CE   HE2  sing N N 210 
LYS CE   HE3  sing N N 211 
LYS NZ   HZ1  sing N N 212 
LYS NZ   HZ2  sing N N 213 
LYS NZ   HZ3  sing N N 214 
LYS OXT  HXT  sing N N 215 
MET N    CA   sing N N 216 
MET N    H    sing N N 217 
MET N    H2   sing N N 218 
MET CA   C    sing N N 219 
MET CA   CB   sing N N 220 
MET CA   HA   sing N N 221 
MET C    O    doub N N 222 
MET C    OXT  sing N N 223 
MET CB   CG   sing N N 224 
MET CB   HB2  sing N N 225 
MET CB   HB3  sing N N 226 
MET CG   SD   sing N N 227 
MET CG   HG2  sing N N 228 
MET CG   HG3  sing N N 229 
MET SD   CE   sing N N 230 
MET CE   HE1  sing N N 231 
MET CE   HE2  sing N N 232 
MET CE   HE3  sing N N 233 
MET OXT  HXT  sing N N 234 
PHE N    CA   sing N N 235 
PHE N    H    sing N N 236 
PHE N    H2   sing N N 237 
PHE CA   C    sing N N 238 
PHE CA   CB   sing N N 239 
PHE CA   HA   sing N N 240 
PHE C    O    doub N N 241 
PHE C    OXT  sing N N 242 
PHE CB   CG   sing N N 243 
PHE CB   HB2  sing N N 244 
PHE CB   HB3  sing N N 245 
PHE CG   CD1  doub Y N 246 
PHE CG   CD2  sing Y N 247 
PHE CD1  CE1  sing Y N 248 
PHE CD1  HD1  sing N N 249 
PHE CD2  CE2  doub Y N 250 
PHE CD2  HD2  sing N N 251 
PHE CE1  CZ   doub Y N 252 
PHE CE1  HE1  sing N N 253 
PHE CE2  CZ   sing Y N 254 
PHE CE2  HE2  sing N N 255 
PHE CZ   HZ   sing N N 256 
PHE OXT  HXT  sing N N 257 
POV N    C12  sing N N 258 
POV N    C13  sing N N 259 
POV N    C14  sing N N 260 
POV N    C15  sing N N 261 
POV P    O11  sing N N 262 
POV P    O12  sing N N 263 
POV P    O13  sing N N 264 
POV P    O14  doub N N 265 
POV C1   C2   sing N N 266 
POV C1   O11  sing N N 267 
POV C1   H1   sing N N 268 
POV C1   H1A  sing N N 269 
POV C2   C3   sing N N 270 
POV C2   O21  sing N N 271 
POV C2   H2   sing N N 272 
POV C3   O31  sing N N 273 
POV C3   H3   sing N N 274 
POV C3   H3A  sing N N 275 
POV C210 C211 sing N N 276 
POV C210 C29  doub N Z 277 
POV C210 H210 sing N N 278 
POV C310 C311 sing N N 279 
POV C310 C39  sing N N 280 
POV C310 H310 sing N N 281 
POV C310 H31A sing N N 282 
POV C11  C12  sing N N 283 
POV C11  O12  sing N N 284 
POV C11  H11  sing N N 285 
POV C11  H11A sing N N 286 
POV C211 C212 sing N N 287 
POV C211 H211 sing N N 288 
POV C211 H21A sing N N 289 
POV C311 C312 sing N N 290 
POV C311 H311 sing N N 291 
POV C311 H31B sing N N 292 
POV C12  H12  sing N N 293 
POV C12  H12A sing N N 294 
POV C212 C213 sing N N 295 
POV C212 H212 sing N N 296 
POV C212 H21B sing N N 297 
POV C312 C313 sing N N 298 
POV C312 H312 sing N N 299 
POV C312 H31C sing N N 300 
POV C13  H13  sing N N 301 
POV C13  H13A sing N N 302 
POV C13  H13B sing N N 303 
POV C213 C214 sing N N 304 
POV C213 H213 sing N N 305 
POV C213 H21C sing N N 306 
POV C313 C314 sing N N 307 
POV C313 H313 sing N N 308 
POV C313 H31D sing N N 309 
POV C14  H14  sing N N 310 
POV C14  H14A sing N N 311 
POV C14  H14B sing N N 312 
POV C214 C215 sing N N 313 
POV C214 H214 sing N N 314 
POV C214 H21D sing N N 315 
POV C314 C315 sing N N 316 
POV C314 H314 sing N N 317 
POV C314 H31E sing N N 318 
POV C15  H15  sing N N 319 
POV C15  H15A sing N N 320 
POV C15  H15B sing N N 321 
POV C215 C216 sing N N 322 
POV C215 H215 sing N N 323 
POV C215 H21E sing N N 324 
POV C315 C316 sing N N 325 
POV C315 H315 sing N N 326 
POV C315 H31F sing N N 327 
POV C216 C217 sing N N 328 
POV C216 H216 sing N N 329 
POV C216 H21F sing N N 330 
POV C316 H316 sing N N 331 
POV C316 H31G sing N N 332 
POV C316 H31H sing N N 333 
POV C217 C218 sing N N 334 
POV C217 H217 sing N N 335 
POV C217 H21G sing N N 336 
POV C218 H218 sing N N 337 
POV C218 H21H sing N N 338 
POV C218 H21J sing N N 339 
POV C21  O21  sing N N 340 
POV C21  C22  sing N N 341 
POV C21  O22  doub N N 342 
POV C22  C23  sing N N 343 
POV C22  H22  sing N N 344 
POV C22  H22A sing N N 345 
POV C23  C24  sing N N 346 
POV C23  H23  sing N N 347 
POV C23  H23A sing N N 348 
POV C24  C25  sing N N 349 
POV C24  H24  sing N N 350 
POV C24  H24A sing N N 351 
POV C25  C26  sing N N 352 
POV C25  H25  sing N N 353 
POV C25  H25A sing N N 354 
POV C26  C27  sing N N 355 
POV C26  H26  sing N N 356 
POV C26  H26A sing N N 357 
POV C27  C28  sing N N 358 
POV C27  H27  sing N N 359 
POV C27  H27A sing N N 360 
POV C28  C29  sing N N 361 
POV C28  H28  sing N N 362 
POV C28  H28A sing N N 363 
POV C29  H29  sing N N 364 
POV C31  O31  sing N N 365 
POV C31  C32  sing N N 366 
POV C31  O32  doub N N 367 
POV C32  C33  sing N N 368 
POV C32  H32  sing N N 369 
POV C32  H32A sing N N 370 
POV C33  C34  sing N N 371 
POV C33  H33  sing N N 372 
POV C33  H33A sing N N 373 
POV C34  C35  sing N N 374 
POV C34  H34  sing N N 375 
POV C34  H34A sing N N 376 
POV C35  C36  sing N N 377 
POV C35  H35  sing N N 378 
POV C35  H35A sing N N 379 
POV C36  C37  sing N N 380 
POV C36  H36  sing N N 381 
POV C36  H36A sing N N 382 
POV C37  C38  sing N N 383 
POV C37  H37  sing N N 384 
POV C37  H37A sing N N 385 
POV C38  C39  sing N N 386 
POV C38  H38  sing N N 387 
POV C38  H38A sing N N 388 
POV C39  H39  sing N N 389 
POV C39  H39A sing N N 390 
PRO N    CA   sing N N 391 
PRO N    CD   sing N N 392 
PRO N    H    sing N N 393 
PRO CA   C    sing N N 394 
PRO CA   CB   sing N N 395 
PRO CA   HA   sing N N 396 
PRO C    O    doub N N 397 
PRO C    OXT  sing N N 398 
PRO CB   CG   sing N N 399 
PRO CB   HB2  sing N N 400 
PRO CB   HB3  sing N N 401 
PRO CG   CD   sing N N 402 
PRO CG   HG2  sing N N 403 
PRO CG   HG3  sing N N 404 
PRO CD   HD2  sing N N 405 
PRO CD   HD3  sing N N 406 
PRO OXT  HXT  sing N N 407 
SER N    CA   sing N N 408 
SER N    H    sing N N 409 
SER N    H2   sing N N 410 
SER CA   C    sing N N 411 
SER CA   CB   sing N N 412 
SER CA   HA   sing N N 413 
SER C    O    doub N N 414 
SER C    OXT  sing N N 415 
SER CB   OG   sing N N 416 
SER CB   HB2  sing N N 417 
SER CB   HB3  sing N N 418 
SER OG   HG   sing N N 419 
SER OXT  HXT  sing N N 420 
THR N    CA   sing N N 421 
THR N    H    sing N N 422 
THR N    H2   sing N N 423 
THR CA   C    sing N N 424 
THR CA   CB   sing N N 425 
THR CA   HA   sing N N 426 
THR C    O    doub N N 427 
THR C    OXT  sing N N 428 
THR CB   OG1  sing N N 429 
THR CB   CG2  sing N N 430 
THR CB   HB   sing N N 431 
THR OG1  HG1  sing N N 432 
THR CG2  HG21 sing N N 433 
THR CG2  HG22 sing N N 434 
THR CG2  HG23 sing N N 435 
THR OXT  HXT  sing N N 436 
TRP N    CA   sing N N 437 
TRP N    H    sing N N 438 
TRP N    H2   sing N N 439 
TRP CA   C    sing N N 440 
TRP CA   CB   sing N N 441 
TRP CA   HA   sing N N 442 
TRP C    O    doub N N 443 
TRP C    OXT  sing N N 444 
TRP CB   CG   sing N N 445 
TRP CB   HB2  sing N N 446 
TRP CB   HB3  sing N N 447 
TRP CG   CD1  doub Y N 448 
TRP CG   CD2  sing Y N 449 
TRP CD1  NE1  sing Y N 450 
TRP CD1  HD1  sing N N 451 
TRP CD2  CE2  doub Y N 452 
TRP CD2  CE3  sing Y N 453 
TRP NE1  CE2  sing Y N 454 
TRP NE1  HE1  sing N N 455 
TRP CE2  CZ2  sing Y N 456 
TRP CE3  CZ3  doub Y N 457 
TRP CE3  HE3  sing N N 458 
TRP CZ2  CH2  doub Y N 459 
TRP CZ2  HZ2  sing N N 460 
TRP CZ3  CH2  sing Y N 461 
TRP CZ3  HZ3  sing N N 462 
TRP CH2  HH2  sing N N 463 
TRP OXT  HXT  sing N N 464 
TYR N    CA   sing N N 465 
TYR N    H    sing N N 466 
TYR N    H2   sing N N 467 
TYR CA   C    sing N N 468 
TYR CA   CB   sing N N 469 
TYR CA   HA   sing N N 470 
TYR C    O    doub N N 471 
TYR C    OXT  sing N N 472 
TYR CB   CG   sing N N 473 
TYR CB   HB2  sing N N 474 
TYR CB   HB3  sing N N 475 
TYR CG   CD1  doub Y N 476 
TYR CG   CD2  sing Y N 477 
TYR CD1  CE1  sing Y N 478 
TYR CD1  HD1  sing N N 479 
TYR CD2  CE2  doub Y N 480 
TYR CD2  HD2  sing N N 481 
TYR CE1  CZ   doub Y N 482 
TYR CE1  HE1  sing N N 483 
TYR CE2  CZ   sing Y N 484 
TYR CE2  HE2  sing N N 485 
TYR CZ   OH   sing N N 486 
TYR OH   HH   sing N N 487 
TYR OXT  HXT  sing N N 488 
VAL N    CA   sing N N 489 
VAL N    H    sing N N 490 
VAL N    H2   sing N N 491 
VAL CA   C    sing N N 492 
VAL CA   CB   sing N N 493 
VAL CA   HA   sing N N 494 
VAL C    O    doub N N 495 
VAL C    OXT  sing N N 496 
VAL CB   CG1  sing N N 497 
VAL CB   CG2  sing N N 498 
VAL CB   HB   sing N N 499 
VAL CG1  HG11 sing N N 500 
VAL CG1  HG12 sing N N 501 
VAL CG1  HG13 sing N N 502 
VAL CG2  HG21 sing N N 503 
VAL CG2  HG22 sing N N 504 
VAL CG2  HG23 sing N N 505 
VAL OXT  HXT  sing N N 506 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2025-04-09 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           9UET 
_em_admin.last_update        2025-06-18 
_em_admin.map_release_date   2025-06-18 
_em_admin.title              'Cryo-EM structure of human choline-phosphotransferase 1' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                45.1 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 'HEK 293F' 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              pCAG 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
_em_software.reference_DOI 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? ? 
MASKING                    ? 3  ? ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? ? 
# 
_em_specimen.concentration           5 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Chinese Academy of Sciences' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9UET 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N    . ALA A 1 16  ? 118.112 93.561  125.939 1.00 97.25  ? 16  ALA A N    1 
ATOM   2    C  CA   . ALA A 1 16  ? 116.720 93.960  125.768 1.00 97.25  ? 16  ALA A CA   1 
ATOM   3    C  C    . ALA A 1 16  ? 115.953 92.929  124.951 1.00 97.25  ? 16  ALA A C    1 
ATOM   4    O  O    . ALA A 1 16  ? 114.724 92.908  124.958 1.00 97.25  ? 16  ALA A O    1 
ATOM   5    C  CB   . ALA A 1 16  ? 116.636 95.326  125.109 1.00 97.25  ? 16  ALA A CB   1 
ATOM   6    N  N    . LEU A 1 17  ? 116.688 92.077  124.236 1.00 96.53  ? 17  LEU A N    1 
ATOM   7    C  CA   . LEU A 1 17  ? 116.051 91.019  123.460 1.00 96.53  ? 17  LEU A CA   1 
ATOM   8    C  C    . LEU A 1 17  ? 115.445 89.962  124.370 1.00 96.53  ? 17  LEU A C    1 
ATOM   9    O  O    . LEU A 1 17  ? 114.280 89.583  124.208 1.00 96.53  ? 17  LEU A O    1 
ATOM   10   C  CB   . LEU A 1 17  ? 117.069 90.389  122.508 1.00 96.53  ? 17  LEU A CB   1 
ATOM   11   C  CG   . LEU A 1 17  ? 116.606 89.331  121.504 1.00 96.53  ? 17  LEU A CG   1 
ATOM   12   C  CD1  . LEU A 1 17  ? 117.280 89.550  120.163 1.00 96.53  ? 17  LEU A CD1  1 
ATOM   13   C  CD2  . LEU A 1 17  ? 116.910 87.930  122.018 1.00 96.53  ? 17  LEU A CD2  1 
ATOM   14   N  N    . SER A 1 18  ? 116.215 89.484  125.343 1.00 97.67  ? 18  SER A N    1 
ATOM   15   C  CA   . SER A 1 18  ? 115.821 88.330  126.136 1.00 97.67  ? 18  SER A CA   1 
ATOM   16   C  C    . SER A 1 18  ? 114.959 88.679  127.341 1.00 97.67  ? 18  SER A C    1 
ATOM   17   O  O    . SER A 1 18  ? 114.503 87.769  128.038 1.00 97.67  ? 18  SER A O    1 
ATOM   18   C  CB   . SER A 1 18  ? 117.067 87.570  126.605 1.00 97.67  ? 18  SER A CB   1 
ATOM   19   O  OG   . SER A 1 18  ? 116.718 86.308  127.141 1.00 97.67  ? 18  SER A OG   1 
ATOM   20   N  N    . GLU A 1 19  ? 114.732 89.961  127.613 1.00 99.29  ? 19  GLU A N    1 
ATOM   21   C  CA   . GLU A 1 19  ? 113.869 90.396  128.711 1.00 99.29  ? 19  GLU A CA   1 
ATOM   22   C  C    . GLU A 1 19  ? 112.896 91.456  128.207 1.00 99.29  ? 19  GLU A C    1 
ATOM   23   O  O    . GLU A 1 19  ? 113.055 92.648  128.498 1.00 99.29  ? 19  GLU A O    1 
ATOM   24   C  CB   . GLU A 1 19  ? 114.700 90.944  129.872 1.00 99.29  ? 19  GLU A CB   1 
ATOM   25   C  CG   . GLU A 1 19  ? 115.649 89.948  130.522 1.00 99.29  ? 19  GLU A CG   1 
ATOM   26   C  CD   . GLU A 1 19  ? 114.940 88.970  131.433 1.00 99.29  ? 19  GLU A CD   1 
ATOM   27   O  OE1  . GLU A 1 19  ? 113.922 89.354  132.041 1.00 99.29  ? 19  GLU A OE1  1 
ATOM   28   O  OE2  . GLU A 1 19  ? 115.408 87.817  131.546 1.00 99.29  ? 19  GLU A OE2  1 
ATOM   29   N  N    . PRO A 1 20  ? 111.871 91.061  127.444 1.00 96.65  ? 20  PRO A N    1 
ATOM   30   C  CA   . PRO A 1 20  ? 110.913 92.053  126.938 1.00 96.65  ? 20  PRO A CA   1 
ATOM   31   C  C    . PRO A 1 20  ? 109.932 92.580  127.975 1.00 96.65  ? 20  PRO A C    1 
ATOM   32   O  O    . PRO A 1 20  ? 109.182 93.512  127.661 1.00 96.65  ? 20  PRO A O    1 
ATOM   33   C  CB   . PRO A 1 20  ? 110.177 91.293  125.832 1.00 96.65  ? 20  PRO A CB   1 
ATOM   34   C  CG   . PRO A 1 20  ? 110.276 89.881  126.233 1.00 96.65  ? 20  PRO A CG   1 
ATOM   35   C  CD   . PRO A 1 20  ? 111.613 89.725  126.882 1.00 96.65  ? 20  PRO A CD   1 
ATOM   36   N  N    . LEU A 1 21  ? 109.905 92.032  129.188 1.00 101.48 ? 21  LEU A N    1 
ATOM   37   C  CA   . LEU A 1 21  ? 109.020 92.518  130.235 1.00 101.48 ? 21  LEU A CA   1 
ATOM   38   C  C    . LEU A 1 21  ? 109.818 92.954  131.456 1.00 101.48 ? 21  LEU A C    1 
ATOM   39   O  O    . LEU A 1 21  ? 110.971 92.561  131.649 1.00 101.48 ? 21  LEU A O    1 
ATOM   40   C  CB   . LEU A 1 21  ? 108.002 91.457  130.655 1.00 101.48 ? 21  LEU A CB   1 
ATOM   41   C  CG   . LEU A 1 21  ? 107.110 90.895  129.558 1.00 101.48 ? 21  LEU A CG   1 
ATOM   42   C  CD1  . LEU A 1 21  ? 106.076 89.963  130.156 1.00 101.48 ? 21  LEU A CD1  1 
ATOM   43   C  CD2  . LEU A 1 21  ? 106.450 92.010  128.780 1.00 101.48 ? 21  LEU A CD2  1 
ATOM   44   N  N    . SER A 1 22  ? 109.181 93.774  132.285 1.00 107.03 ? 22  SER A N    1 
ATOM   45   C  CA   . SER A 1 22  ? 109.749 94.226  133.547 1.00 107.03 ? 22  SER A CA   1 
ATOM   46   C  C    . SER A 1 22  ? 109.191 93.399  134.699 1.00 107.03 ? 22  SER A C    1 
ATOM   47   O  O    . SER A 1 22  ? 108.256 92.612  134.540 1.00 107.03 ? 22  SER A O    1 
ATOM   48   C  CB   . SER A 1 22  ? 109.458 95.713  133.767 1.00 107.03 ? 22  SER A CB   1 
ATOM   49   O  OG   . SER A 1 22  ? 108.116 95.910  134.173 1.00 107.03 ? 22  SER A OG   1 
ATOM   50   N  N    . ALA A 1 23  ? 109.787 93.590  135.878 1.00 111.97 ? 23  ALA A N    1 
ATOM   51   C  CA   . ALA A 1 23  ? 109.347 92.853  137.060 1.00 111.97 ? 23  ALA A CA   1 
ATOM   52   C  C    . ALA A 1 23  ? 107.930 93.240  137.462 1.00 111.97 ? 23  ALA A C    1 
ATOM   53   O  O    . ALA A 1 23  ? 107.131 92.380  137.857 1.00 111.97 ? 23  ALA A O    1 
ATOM   54   C  CB   . ALA A 1 23  ? 110.318 93.089  138.215 1.00 111.97 ? 23  ALA A CB   1 
ATOM   55   N  N    . ALA A 1 24  ? 107.596 94.526  137.362 1.00 109.87 ? 24  ALA A N    1 
ATOM   56   C  CA   . ALA A 1 24  ? 106.249 94.962  137.711 1.00 109.87 ? 24  ALA A CA   1 
ATOM   57   C  C    . ALA A 1 24  ? 105.226 94.433  136.716 1.00 109.87 ? 24  ALA A C    1 
ATOM   58   O  O    . ALA A 1 24  ? 104.085 94.128  137.089 1.00 109.87 ? 24  ALA A O    1 
ATOM   59   C  CB   . ALA A 1 24  ? 106.194 96.487  137.781 1.00 109.87 ? 24  ALA A CB   1 
ATOM   60   N  N    . GLN A 1 25  ? 105.603 94.354  135.437 1.00 105.47 ? 25  GLN A N    1 
ATOM   61   C  CA   . GLN A 1 25  ? 104.710 93.759  134.450 1.00 105.47 ? 25  GLN A CA   1 
ATOM   62   C  C    . GLN A 1 25  ? 104.462 92.294  134.763 1.00 105.47 ? 25  GLN A C    1 
ATOM   63   O  O    . GLN A 1 25  ? 103.334 91.804  134.637 1.00 105.47 ? 25  GLN A O    1 
ATOM   64   C  CB   . GLN A 1 25  ? 105.288 93.922  133.047 1.00 105.47 ? 25  GLN A CB   1 
ATOM   65   C  CG   . GLN A 1 25  ? 104.664 95.052  132.253 1.00 105.47 ? 25  GLN A CG   1 
ATOM   66   C  CD   . GLN A 1 25  ? 105.263 95.189  130.876 1.00 105.47 ? 25  GLN A CD   1 
ATOM   67   O  OE1  . GLN A 1 25  ? 106.351 94.686  130.612 1.00 105.47 ? 25  GLN A OE1  1 
ATOM   68   N  NE2  . GLN A 1 25  ? 104.553 95.874  129.986 1.00 105.47 ? 25  GLN A NE2  1 
ATOM   69   N  N    . LEU A 1 26  ? 105.504 91.584  135.197 1.00 109.72 ? 26  LEU A N    1 
ATOM   70   C  CA   . LEU A 1 26  ? 105.322 90.206  135.634 1.00 109.72 ? 26  LEU A CA   1 
ATOM   71   C  C    . LEU A 1 26  ? 104.409 90.136  136.849 1.00 109.72 ? 26  LEU A C    1 
ATOM   72   O  O    . LEU A 1 26  ? 103.622 89.195  136.993 1.00 109.72 ? 26  LEU A O    1 
ATOM   73   C  CB   . LEU A 1 26  ? 106.680 89.578  135.938 1.00 109.72 ? 26  LEU A CB   1 
ATOM   74   C  CG   . LEU A 1 26  ? 107.533 89.291  134.707 1.00 109.72 ? 26  LEU A CG   1 
ATOM   75   C  CD1  . LEU A 1 26  ? 109.004 89.319  135.061 1.00 109.72 ? 26  LEU A CD1  1 
ATOM   76   C  CD2  . LEU A 1 26  ? 107.158 87.962  134.103 1.00 109.72 ? 26  LEU A CD2  1 
ATOM   77   N  N    . ARG A 1 27  ? 104.482 91.142  137.726 1.00 113.29 ? 27  ARG A N    1 
ATOM   78   C  CA   . ARG A 1 27  ? 103.605 91.158  138.891 1.00 113.29 ? 27  ARG A CA   1 
ATOM   79   C  C    . ARG A 1 27  ? 102.143 91.333  138.491 1.00 113.29 ? 27  ARG A C    1 
ATOM   80   O  O    . ARG A 1 27  ? 101.272 90.603  138.983 1.00 113.29 ? 27  ARG A O    1 
ATOM   81   C  CB   . ARG A 1 27  ? 104.038 92.256  139.862 1.00 113.29 ? 27  ARG A CB   1 
ATOM   82   C  CG   . ARG A 1 27  ? 105.156 91.820  140.788 1.00 113.29 ? 27  ARG A CG   1 
ATOM   83   C  CD   . ARG A 1 27  ? 104.607 90.971  141.926 1.00 113.29 ? 27  ARG A CD   1 
ATOM   84   N  NE   . ARG A 1 27  ? 105.669 90.334  142.697 1.00 113.29 ? 27  ARG A NE   1 
ATOM   85   C  CZ   . ARG A 1 27  ? 105.459 89.509  143.716 1.00 113.29 ? 27  ARG A CZ   1 
ATOM   86   N  NH1  . ARG A 1 27  ? 104.223 89.220  144.096 1.00 113.29 ? 27  ARG A NH1  1 
ATOM   87   N  NH2  . ARG A 1 27  ? 106.485 88.972  144.361 1.00 113.29 ? 27  ARG A NH2  1 
ATOM   88   N  N    . ARG A 1 28  ? 101.847 92.284  137.595 1.00 108.81 ? 28  ARG A N    1 
ATOM   89   C  CA   . ARG A 1 28  ? 100.457 92.403  137.157 1.00 108.81 ? 28  ARG A CA   1 
ATOM   90   C  C    . ARG A 1 28  ? 100.004 91.179  136.369 1.00 108.81 ? 28  ARG A C    1 
ATOM   91   O  O    . ARG A 1 28  ? 98.824  90.815  136.435 1.00 108.81 ? 28  ARG A O    1 
ATOM   92   C  CB   . ARG A 1 28  ? 100.175 93.667  136.330 1.00 108.81 ? 28  ARG A CB   1 
ATOM   93   C  CG   . ARG A 1 28  ? 100.299 94.968  137.123 1.00 108.81 ? 28  ARG A CG   1 
ATOM   94   C  CD   . ARG A 1 28  ? 99.984  96.231  136.357 1.00 108.81 ? 28  ARG A CD   1 
ATOM   95   N  NE   . ARG A 1 28  ? 100.200 97.415  137.183 1.00 108.81 ? 28  ARG A NE   1 
ATOM   96   C  CZ   . ARG A 1 28  ? 100.101 98.648  136.688 1.00 108.81 ? 28  ARG A CZ   1 
ATOM   97   N  NH1  . ARG A 1 28  ? 99.797  98.814  135.408 1.00 108.81 ? 28  ARG A NH1  1 
ATOM   98   N  NH2  . ARG A 1 28  ? 100.301 99.714  137.444 1.00 108.81 ? 28  ARG A NH2  1 
ATOM   99   N  N    . LEU A 1 29  ? 100.906 90.535  135.624 1.00 104.49 ? 29  LEU A N    1 
ATOM   100  C  CA   . LEU A 1 29  ? 100.532 89.307  134.924 1.00 104.49 ? 29  LEU A CA   1 
ATOM   101  C  C    . LEU A 1 29  ? 100.193 88.199  135.908 1.00 104.49 ? 29  LEU A C    1 
ATOM   102  O  O    . LEU A 1 29  ? 99.262  87.419  135.675 1.00 104.49 ? 29  LEU A O    1 
ATOM   103  C  CB   . LEU A 1 29  ? 101.652 88.873  133.981 1.00 104.49 ? 29  LEU A CB   1 
ATOM   104  C  CG   . LEU A 1 29  ? 101.375 87.698  133.041 1.00 104.49 ? 29  LEU A CG   1 
ATOM   105  C  CD1  . LEU A 1 29  ? 101.931 87.989  131.668 1.00 104.49 ? 29  LEU A CD1  1 
ATOM   106  C  CD2  . LEU A 1 29  ? 102.011 86.436  133.584 1.00 104.49 ? 29  LEU A CD2  1 
ATOM   107  N  N    . GLU A 1 30  ? 100.938 88.109  137.009 1.00 112.82 ? 30  GLU A N    1 
ATOM   108  C  CA   . GLU A 1 30  ? 100.591 87.160  138.057 1.00 112.82 ? 30  GLU A CA   1 
ATOM   109  C  C    . GLU A 1 30  ? 99.259  87.515  138.704 1.00 112.82 ? 30  GLU A C    1 
ATOM   110  O  O    . GLU A 1 30  ? 98.509  86.620  139.109 1.00 112.82 ? 30  GLU A O    1 
ATOM   111  C  CB   . GLU A 1 30  ? 101.705 87.106  139.100 1.00 112.82 ? 30  GLU A CB   1 
ATOM   112  C  CG   . GLU A 1 30  ? 101.513 86.050  140.173 1.00 112.82 ? 30  GLU A CG   1 
ATOM   113  C  CD   . GLU A 1 30  ? 101.182 84.687  139.600 1.00 112.82 ? 30  GLU A CD   1 
ATOM   114  O  OE1  . GLU A 1 30  ? 100.184 84.083  140.050 1.00 112.82 ? 30  GLU A OE1  1 
ATOM   115  O  OE2  . GLU A 1 30  ? 101.914 84.217  138.706 1.00 112.82 ? 30  GLU A OE2  1 
ATOM   116  N  N    . GLU A 1 31  ? 98.944  88.807  138.801 1.00 113.41 ? 31  GLU A N    1 
ATOM   117  C  CA   . GLU A 1 31  ? 97.683  89.227  139.400 1.00 113.41 ? 31  GLU A CA   1 
ATOM   118  C  C    . GLU A 1 31  ? 96.479  88.959  138.501 1.00 113.41 ? 31  GLU A C    1 
ATOM   119  O  O    . GLU A 1 31  ? 95.366  88.805  139.015 1.00 113.41 ? 31  GLU A O    1 
ATOM   120  C  CB   . GLU A 1 31  ? 97.773  90.715  139.765 1.00 113.41 ? 31  GLU A CB   1 
ATOM   121  C  CG   . GLU A 1 31  ? 96.635  91.288  140.617 1.00 113.41 ? 31  GLU A CG   1 
ATOM   122  C  CD   . GLU A 1 31  ? 95.417  91.704  139.808 1.00 113.41 ? 31  GLU A CD   1 
ATOM   123  O  OE1  . GLU A 1 31  ? 95.582  92.074  138.627 1.00 113.41 ? 31  GLU A OE1  1 
ATOM   124  O  OE2  . GLU A 1 31  ? 94.296  91.660  140.358 1.00 113.41 ? 31  GLU A OE2  1 
ATOM   125  N  N    . HIS A 1 32  ? 96.677  88.856  137.187 1.00 107.93 ? 32  HIS A N    1 
ATOM   126  C  CA   . HIS A 1 32  ? 95.560  88.773  136.252 1.00 107.93 ? 32  HIS A CA   1 
ATOM   127  C  C    . HIS A 1 32  ? 94.788  87.468  136.408 1.00 107.93 ? 32  HIS A C    1 
ATOM   128  O  O    . HIS A 1 32  ? 95.343  86.424  136.757 1.00 107.93 ? 32  HIS A O    1 
ATOM   129  C  CB   . HIS A 1 32  ? 96.055  88.898  134.813 1.00 107.93 ? 32  HIS A CB   1 
ATOM   130  C  CG   . HIS A 1 32  ? 94.956  89.041  133.805 1.00 107.93 ? 32  HIS A CG   1 
ATOM   131  N  ND1  . HIS A 1 32  ? 94.414  87.964  133.138 1.00 107.93 ? 32  HIS A ND1  1 
ATOM   132  C  CD2  . HIS A 1 32  ? 94.304  90.134  133.344 1.00 107.93 ? 32  HIS A CD2  1 
ATOM   133  C  CE1  . HIS A 1 32  ? 93.471  88.387  132.315 1.00 107.93 ? 32  HIS A CE1  1 
ATOM   134  N  NE2  . HIS A 1 32  ? 93.386  89.701  132.419 1.00 107.93 ? 32  HIS A NE2  1 
ATOM   135  N  N    . ARG A 1 33  ? 93.485  87.543  136.139 1.00 114.91 ? 33  ARG A N    1 
ATOM   136  C  CA   . ARG A 1 33  ? 92.600  86.390  136.156 1.00 114.91 ? 33  ARG A CA   1 
ATOM   137  C  C    . ARG A 1 33  ? 91.780  86.369  134.876 1.00 114.91 ? 33  ARG A C    1 
ATOM   138  O  O    . ARG A 1 33  ? 91.321  87.414  134.403 1.00 114.91 ? 33  ARG A O    1 
ATOM   139  C  CB   . ARG A 1 33  ? 91.678  86.416  137.382 1.00 114.91 ? 33  ARG A CB   1 
ATOM   140  C  CG   . ARG A 1 33  ? 90.977  85.096  137.684 1.00 114.91 ? 33  ARG A CG   1 
ATOM   141  C  CD   . ARG A 1 33  ? 91.881  83.891  137.440 1.00 114.91 ? 33  ARG A CD   1 
ATOM   142  N  NE   . ARG A 1 33  ? 92.850  83.692  138.514 1.00 114.91 ? 33  ARG A NE   1 
ATOM   143  C  CZ   . ARG A 1 33  ? 93.685  82.662  138.585 1.00 114.91 ? 33  ARG A CZ   1 
ATOM   144  N  NH1  . ARG A 1 33  ? 93.671  81.729  137.642 1.00 114.91 ? 33  ARG A NH1  1 
ATOM   145  N  NH2  . ARG A 1 33  ? 94.535  82.559  139.598 1.00 114.91 ? 33  ARG A NH2  1 
ATOM   146  N  N    . TYR A 1 34  ? 91.598  85.175  134.316 1.00 112.70 ? 34  TYR A N    1 
ATOM   147  C  CA   . TYR A 1 34  ? 90.903  85.022  133.045 1.00 112.70 ? 34  TYR A CA   1 
ATOM   148  C  C    . TYR A 1 34  ? 89.394  84.982  133.247 1.00 112.70 ? 34  TYR A C    1 
ATOM   149  O  O    . TYR A 1 34  ? 88.896  84.382  134.203 1.00 112.70 ? 34  TYR A O    1 
ATOM   150  C  CB   . TYR A 1 34  ? 91.374  83.749  132.339 1.00 112.70 ? 34  TYR A CB   1 
ATOM   151  C  CG   . TYR A 1 34  ? 90.716  83.504  131.001 1.00 112.70 ? 34  TYR A CG   1 
ATOM   152  C  CD1  . TYR A 1 34  ? 90.673  84.498  130.031 1.00 112.70 ? 34  TYR A CD1  1 
ATOM   153  C  CD2  . TYR A 1 34  ? 90.147  82.276  130.702 1.00 112.70 ? 34  TYR A CD2  1 
ATOM   154  C  CE1  . TYR A 1 34  ? 90.072  84.278  128.807 1.00 112.70 ? 34  TYR A CE1  1 
ATOM   155  C  CE2  . TYR A 1 34  ? 89.542  82.045  129.484 1.00 112.70 ? 34  TYR A CE2  1 
ATOM   156  C  CZ   . TYR A 1 34  ? 89.510  83.048  128.539 1.00 112.70 ? 34  TYR A CZ   1 
ATOM   157  O  OH   . TYR A 1 34  ? 88.910  82.819  127.324 1.00 112.70 ? 34  TYR A OH   1 
ATOM   158  N  N    . SER A 1 35  ? 88.670  85.630  132.336 1.00 112.14 ? 35  SER A N    1 
ATOM   159  C  CA   . SER A 1 35  ? 87.217  85.660  132.389 1.00 112.14 ? 35  SER A CA   1 
ATOM   160  C  C    . SER A 1 35  ? 86.663  85.737  130.973 1.00 112.14 ? 35  SER A C    1 
ATOM   161  O  O    . SER A 1 35  ? 87.327  86.235  130.060 1.00 112.14 ? 35  SER A O    1 
ATOM   162  C  CB   . SER A 1 35  ? 86.707  86.840  133.220 1.00 112.14 ? 35  SER A CB   1 
ATOM   163  O  OG   . SER A 1 35  ? 87.077  86.700  134.583 1.00 112.14 ? 35  SER A OG   1 
ATOM   164  N  N    . ALA A 1 36  ? 85.439  85.240  130.802 1.00 112.23 ? 36  ALA A N    1 
ATOM   165  C  CA   . ALA A 1 36  ? 84.773  85.249  129.509 1.00 112.23 ? 36  ALA A CA   1 
ATOM   166  C  C    . ALA A 1 36  ? 83.268  85.200  129.726 1.00 112.23 ? 36  ALA A C    1 
ATOM   167  O  O    . ALA A 1 36  ? 82.784  84.594  130.683 1.00 112.23 ? 36  ALA A O    1 
ATOM   168  C  CB   . ALA A 1 36  ? 85.221  84.074  128.633 1.00 112.23 ? 36  ALA A CB   1 
ATOM   169  N  N    . ALA A 1 37  ? 82.531  85.850  128.829 1.00 112.84 ? 37  ALA A N    1 
ATOM   170  C  CA   . ALA A 1 37  ? 81.079  85.960  128.936 1.00 112.84 ? 37  ALA A CA   1 
ATOM   171  C  C    . ALA A 1 37  ? 80.418  85.730  127.581 1.00 112.84 ? 37  ALA A C    1 
ATOM   172  O  O    . ALA A 1 37  ? 79.559  86.495  127.144 1.00 112.84 ? 37  ALA A O    1 
ATOM   173  C  CB   . ALA A 1 37  ? 80.682  87.318  129.511 1.00 112.84 ? 37  ALA A CB   1 
ATOM   174  N  N    . GLY A 1 38  ? 80.819  84.664  126.891 1.00 110.53 ? 38  GLY A N    1 
ATOM   175  C  CA   . GLY A 1 38  ? 80.316  84.442  125.548 1.00 110.53 ? 38  GLY A CA   1 
ATOM   176  C  C    . GLY A 1 38  ? 79.569  83.147  125.306 1.00 110.53 ? 38  GLY A C    1 
ATOM   177  O  O    . GLY A 1 38  ? 80.134  82.057  125.436 1.00 110.53 ? 38  GLY A O    1 
ATOM   178  N  N    . VAL A 1 39  ? 78.292  83.259  124.941 1.00 112.24 ? 39  VAL A N    1 
ATOM   179  C  CA   . VAL A 1 39  ? 77.455  82.123  124.569 1.00 112.24 ? 39  VAL A CA   1 
ATOM   180  C  C    . VAL A 1 39  ? 76.706  82.490  123.297 1.00 112.24 ? 39  VAL A C    1 
ATOM   181  O  O    . VAL A 1 39  ? 76.081  83.554  123.227 1.00 112.24 ? 39  VAL A O    1 
ATOM   182  C  CB   . VAL A 1 39  ? 76.465  81.747  125.690 1.00 112.24 ? 39  VAL A CB   1 
ATOM   183  C  CG1  . VAL A 1 39  ? 75.439  80.742  125.188 1.00 112.24 ? 39  VAL A CG1  1 
ATOM   184  C  CG2  . VAL A 1 39  ? 77.199  81.192  126.899 1.00 112.24 ? 39  VAL A CG2  1 
ATOM   185  N  N    . SER A 1 40  ? 76.759  81.614  122.299 1.00 112.95 ? 40  SER A N    1 
ATOM   186  C  CA   . SER A 1 40  ? 76.041  81.832  121.046 1.00 112.95 ? 40  SER A CA   1 
ATOM   187  C  C    . SER A 1 40  ? 75.421  80.503  120.625 1.00 112.95 ? 40  SER A C    1 
ATOM   188  O  O    . SER A 1 40  ? 75.319  79.560  121.417 1.00 112.95 ? 40  SER A O    1 
ATOM   189  C  CB   . SER A 1 40  ? 76.965  82.429  119.975 1.00 112.95 ? 40  SER A CB   1 
ATOM   190  O  OG   . SER A 1 40  ? 77.861  81.466  119.464 1.00 112.95 ? 40  SER A OG   1 
ATOM   191  N  N    . LEU A 1 41  ? 74.994  80.419  119.365 1.00 115.43 ? 41  LEU A N    1 
ATOM   192  C  CA   . LEU A 1 41  ? 74.187  79.299  118.896 1.00 115.43 ? 41  LEU A CA   1 
ATOM   193  C  C    . LEU A 1 41  ? 74.969  77.998  118.739 1.00 115.43 ? 41  LEU A C    1 
ATOM   194  O  O    . LEU A 1 41  ? 74.494  76.942  119.169 1.00 115.43 ? 41  LEU A O    1 
ATOM   195  C  CB   . LEU A 1 41  ? 73.529  79.656  117.562 1.00 115.43 ? 41  LEU A CB   1 
ATOM   196  C  CG   . LEU A 1 41  ? 72.608  78.586  116.972 1.00 115.43 ? 41  LEU A CG   1 
ATOM   197  C  CD1  . LEU A 1 41  ? 71.365  78.411  117.832 1.00 115.43 ? 41  LEU A CD1  1 
ATOM   198  C  CD2  . LEU A 1 41  ? 72.224  78.924  115.538 1.00 115.43 ? 41  LEU A CD2  1 
ATOM   199  N  N    . LEU A 1 42  ? 76.156  78.037  118.142 1.00 111.48 ? 42  LEU A N    1 
ATOM   200  C  CA   . LEU A 1 42  ? 76.801  76.813  117.679 1.00 111.48 ? 42  LEU A CA   1 
ATOM   201  C  C    . LEU A 1 42  ? 77.646  76.114  118.736 1.00 111.48 ? 42  LEU A C    1 
ATOM   202  O  O    . LEU A 1 42  ? 78.130  75.007  118.478 1.00 111.48 ? 42  LEU A O    1 
ATOM   203  C  CB   . LEU A 1 42  ? 77.675  77.102  116.451 1.00 111.48 ? 42  LEU A CB   1 
ATOM   204  C  CG   . LEU A 1 42  ? 77.019  77.121  115.062 1.00 111.48 ? 42  LEU A CG   1 
ATOM   205  C  CD1  . LEU A 1 42  ? 76.467  75.742  114.725 1.00 111.48 ? 42  LEU A CD1  1 
ATOM   206  C  CD2  . LEU A 1 42  ? 75.941  78.191  114.906 1.00 111.48 ? 42  LEU A CD2  1 
ATOM   207  N  N    . GLU A 1 43  ? 77.840  76.714  119.908 1.00 115.62 ? 43  GLU A N    1 
ATOM   208  C  CA   . GLU A 1 43  ? 78.648  76.046  120.930 1.00 115.62 ? 43  GLU A CA   1 
ATOM   209  C  C    . GLU A 1 43  ? 77.944  74.868  121.592 1.00 115.62 ? 43  GLU A C    1 
ATOM   210  O  O    . GLU A 1 43  ? 78.583  73.804  121.721 1.00 115.62 ? 43  GLU A O    1 
ATOM   211  C  CB   . GLU A 1 43  ? 79.162  77.051  121.974 1.00 115.62 ? 43  GLU A CB   1 
ATOM   212  C  CG   . GLU A 1 43  ? 80.188  78.118  121.540 1.00 115.62 ? 43  GLU A CG   1 
ATOM   213  C  CD   . GLU A 1 43  ? 80.576  79.099  122.617 1.00 115.62 ? 43  GLU A CD   1 
ATOM   214  O  OE1  . GLU A 1 43  ? 79.933  79.115  123.686 1.00 115.62 ? 43  GLU A OE1  1 
ATOM   215  O  OE2  . GLU A 1 43  ? 81.549  79.842  122.403 1.00 115.62 ? 43  GLU A OE2  1 
ATOM   216  N  N    . PRO A 1 44  ? 76.686  74.951  122.049 1.00 118.77 ? 44  PRO A N    1 
ATOM   217  C  CA   . PRO A 1 44  ? 76.085  73.829  122.809 1.00 118.77 ? 44  PRO A CA   1 
ATOM   218  C  C    . PRO A 1 44  ? 76.077  72.501  122.055 1.00 118.77 ? 44  PRO A C    1 
ATOM   219  O  O    . PRO A 1 44  ? 76.232  71.453  122.696 1.00 118.77 ? 44  PRO A O    1 
ATOM   220  C  CB   . PRO A 1 44  ? 74.662  74.320  123.104 1.00 118.77 ? 44  PRO A CB   1 
ATOM   221  C  CG   . PRO A 1 44  ? 74.809  75.770  123.190 1.00 118.77 ? 44  PRO A CG   1 
ATOM   222  C  CD   . PRO A 1 44  ? 75.786  76.128  122.111 1.00 118.77 ? 44  PRO A CD   1 
ATOM   223  N  N    . PRO A 1 45  ? 75.895  72.469  120.723 1.00 118.09 ? 45  PRO A N    1 
ATOM   224  C  CA   . PRO A 1 45  ? 76.116  71.180  120.043 1.00 118.09 ? 45  PRO A CA   1 
ATOM   225  C  C    . PRO A 1 45  ? 77.568  70.725  120.038 1.00 118.09 ? 45  PRO A C    1 
ATOM   226  O  O    . PRO A 1 45  ? 77.821  69.531  119.838 1.00 118.09 ? 45  PRO A O    1 
ATOM   227  C  CB   . PRO A 1 45  ? 75.601  71.434  118.618 1.00 118.09 ? 45  PRO A CB   1 
ATOM   228  C  CG   . PRO A 1 45  ? 75.588  72.891  118.467 1.00 118.09 ? 45  PRO A CG   1 
ATOM   229  C  CD   . PRO A 1 45  ? 75.215  73.405  119.809 1.00 118.09 ? 45  PRO A CD   1 
ATOM   230  N  N    . LEU A 1 46  ? 78.528  71.625  120.254 1.00 119.13 ? 46  LEU A N    1 
ATOM   231  C  CA   . LEU A 1 46  ? 79.936  71.258  120.145 1.00 119.13 ? 46  LEU A CA   1 
ATOM   232  C  C    . LEU A 1 46  ? 80.611  71.010  121.488 1.00 119.13 ? 46  LEU A C    1 
ATOM   233  O  O    . LEU A 1 46  ? 81.699  70.423  121.516 1.00 119.13 ? 46  LEU A O    1 
ATOM   234  C  CB   . LEU A 1 46  ? 80.713  72.344  119.394 1.00 119.13 ? 46  LEU A CB   1 
ATOM   235  C  CG   . LEU A 1 46  ? 80.438  72.481  117.894 1.00 119.13 ? 46  LEU A CG   1 
ATOM   236  C  CD1  . LEU A 1 46  ? 81.215  73.649  117.321 1.00 119.13 ? 46  LEU A CD1  1 
ATOM   237  C  CD2  . LEU A 1 46  ? 80.782  71.199  117.158 1.00 119.13 ? 46  LEU A CD2  1 
ATOM   238  N  N    . GLN A 1 47  ? 80.007  71.458  122.591 1.00 122.12 ? 47  GLN A N    1 
ATOM   239  C  CA   . GLN A 1 47  ? 80.614  71.267  123.907 1.00 122.12 ? 47  GLN A CA   1 
ATOM   240  C  C    . GLN A 1 47  ? 80.743  69.787  124.243 1.00 122.12 ? 47  GLN A C    1 
ATOM   241  O  O    . GLN A 1 47  ? 81.792  69.336  124.720 1.00 122.12 ? 47  GLN A O    1 
ATOM   242  C  CB   . GLN A 1 47  ? 79.780  71.985  124.971 1.00 122.12 ? 47  GLN A CB   1 
ATOM   243  C  CG   . GLN A 1 47  ? 79.897  73.533  125.107 1.00 122.12 ? 47  GLN A CG   1 
ATOM   244  C  CD   . GLN A 1 47  ? 81.309  74.147  125.130 1.00 122.12 ? 47  GLN A CD   1 
ATOM   245  O  OE1  . GLN A 1 47  ? 82.333  73.469  125.060 1.00 122.12 ? 47  GLN A OE1  1 
ATOM   246  N  NE2  . GLN A 1 47  ? 81.347  75.472  125.234 1.00 122.12 ? 47  GLN A NE2  1 
ATOM   247  N  N    . LEU A 1 48  ? 79.681  69.017  123.990 1.00 127.81 ? 48  LEU A N    1 
ATOM   248  C  CA   . LEU A 1 48  ? 79.713  67.582  124.245 1.00 127.81 ? 48  LEU A CA   1 
ATOM   249  C  C    . LEU A 1 48  ? 80.754  66.897  123.372 1.00 127.81 ? 48  LEU A C    1 
ATOM   250  O  O    . LEU A 1 48  ? 81.468  66.002  123.834 1.00 127.81 ? 48  LEU A O    1 
ATOM   251  C  CB   . LEU A 1 48  ? 78.332  66.970  124.006 1.00 127.81 ? 48  LEU A CB   1 
ATOM   252  C  CG   . LEU A 1 48  ? 77.302  66.947  125.142 1.00 127.81 ? 48  LEU A CG   1 
ATOM   253  C  CD1  . LEU A 1 48  ? 77.819  66.135  126.325 1.00 127.81 ? 48  LEU A CD1  1 
ATOM   254  C  CD2  . LEU A 1 48  ? 76.883  68.343  125.577 1.00 127.81 ? 48  LEU A CD2  1 
ATOM   255  N  N    . TYR A 1 49  ? 80.846  67.310  122.105 1.00 126.01 ? 49  TYR A N    1 
ATOM   256  C  CA   . TYR A 1 49  ? 81.819  66.718  121.191 1.00 126.01 ? 49  TYR A CA   1 
ATOM   257  C  C    . TYR A 1 49  ? 83.240  66.998  121.659 1.00 126.01 ? 49  TYR A C    1 
ATOM   258  O  O    . TYR A 1 49  ? 84.099  66.106  121.649 1.00 126.01 ? 49  TYR A O    1 
ATOM   259  C  CB   . TYR A 1 49  ? 81.581  67.271  119.784 1.00 126.01 ? 49  TYR A CB   1 
ATOM   260  C  CG   . TYR A 1 49  ? 82.221  66.494  118.656 1.00 126.01 ? 49  TYR A CG   1 
ATOM   261  C  CD1  . TYR A 1 49  ? 81.606  65.361  118.143 1.00 126.01 ? 49  TYR A CD1  1 
ATOM   262  C  CD2  . TYR A 1 49  ? 83.414  66.911  118.081 1.00 126.01 ? 49  TYR A CD2  1 
ATOM   263  C  CE1  . TYR A 1 49  ? 82.169  64.649  117.103 1.00 126.01 ? 49  TYR A CE1  1 
ATOM   264  C  CE2  . TYR A 1 49  ? 83.983  66.205  117.037 1.00 126.01 ? 49  TYR A CE2  1 
ATOM   265  C  CZ   . TYR A 1 49  ? 83.356  65.073  116.554 1.00 126.01 ? 49  TYR A CZ   1 
ATOM   266  O  OH   . TYR A 1 49  ? 83.912  64.361  115.517 1.00 126.01 ? 49  TYR A OH   1 
ATOM   267  N  N    . TRP A 1 50  ? 83.497  68.231  122.103 1.00 117.80 ? 50  TRP A N    1 
ATOM   268  C  CA   . TRP A 1 50  ? 84.822  68.592  122.594 1.00 117.80 ? 50  TRP A CA   1 
ATOM   269  C  C    . TRP A 1 50  ? 85.179  67.811  123.852 1.00 117.80 ? 50  TRP A C    1 
ATOM   270  O  O    . TRP A 1 50  ? 86.305  67.323  123.985 1.00 117.80 ? 50  TRP A O    1 
ATOM   271  C  CB   . TRP A 1 50  ? 84.888  70.091  122.860 1.00 117.80 ? 50  TRP A CB   1 
ATOM   272  C  CG   . TRP A 1 50  ? 84.918  70.905  121.613 1.00 117.80 ? 50  TRP A CG   1 
ATOM   273  C  CD1  . TRP A 1 50  ? 85.472  70.555  120.419 1.00 117.80 ? 50  TRP A CD1  1 
ATOM   274  C  CD2  . TRP A 1 50  ? 84.348  72.201  121.429 1.00 117.80 ? 50  TRP A CD2  1 
ATOM   275  N  NE1  . TRP A 1 50  ? 85.293  71.562  119.503 1.00 117.80 ? 50  TRP A NE1  1 
ATOM   276  C  CE2  . TRP A 1 50  ? 84.606  72.584  120.103 1.00 117.80 ? 50  TRP A CE2  1 
ATOM   277  C  CE3  . TRP A 1 50  ? 83.658  73.079  122.261 1.00 117.80 ? 50  TRP A CE3  1 
ATOM   278  C  CZ2  . TRP A 1 50  ? 84.190  73.805  119.588 1.00 117.80 ? 50  TRP A CZ2  1 
ATOM   279  C  CZ3  . TRP A 1 50  ? 83.246  74.287  121.751 1.00 117.80 ? 50  TRP A CZ3  1 
ATOM   280  C  CH2  . TRP A 1 50  ? 83.513  74.641  120.427 1.00 117.80 ? 50  TRP A CH2  1 
ATOM   281  N  N    . THR A 1 51  ? 84.224  67.655  124.773 1.00 123.01 ? 51  THR A N    1 
ATOM   282  C  CA   . THR A 1 51  ? 84.487  66.865  125.972 1.00 123.01 ? 51  THR A CA   1 
ATOM   283  C  C    . THR A 1 51  ? 84.747  65.402  125.625 1.00 123.01 ? 51  THR A C    1 
ATOM   284  O  O    . THR A 1 51  ? 85.612  64.754  126.236 1.00 123.01 ? 51  THR A O    1 
ATOM   285  C  CB   . THR A 1 51  ? 83.311  66.981  126.941 1.00 123.01 ? 51  THR A CB   1 
ATOM   286  O  OG1  . THR A 1 51  ? 82.876  68.345  127.002 1.00 123.01 ? 51  THR A OG1  1 
ATOM   287  C  CG2  . THR A 1 51  ? 83.725  66.530  128.329 1.00 123.01 ? 51  THR A CG2  1 
ATOM   288  N  N    . TRP A 1 52  ? 83.995  64.876  124.646 1.00 128.22 ? 52  TRP A N    1 
ATOM   289  C  CA   . TRP A 1 52  ? 84.141  63.486  124.230 1.00 128.22 ? 52  TRP A CA   1 
ATOM   290  C  C    . TRP A 1 52  ? 85.507  63.229  123.614 1.00 128.22 ? 52  TRP A C    1 
ATOM   291  O  O    . TRP A 1 52  ? 86.110  62.174  123.841 1.00 128.22 ? 52  TRP A O    1 
ATOM   292  C  CB   . TRP A 1 52  ? 83.037  63.108  123.245 1.00 128.22 ? 52  TRP A CB   1 
ATOM   293  C  CG   . TRP A 1 52  ? 83.216  61.738  122.670 1.00 128.22 ? 52  TRP A CG   1 
ATOM   294  C  CD1  . TRP A 1 52  ? 83.462  60.587  123.356 1.00 128.22 ? 52  TRP A CD1  1 
ATOM   295  C  CD2  . TRP A 1 52  ? 83.169  61.374  121.286 1.00 128.22 ? 52  TRP A CD2  1 
ATOM   296  N  NE1  . TRP A 1 52  ? 83.572  59.529  122.489 1.00 128.22 ? 52  TRP A NE1  1 
ATOM   297  C  CE2  . TRP A 1 52  ? 83.394  59.988  121.209 1.00 128.22 ? 52  TRP A CE2  1 
ATOM   298  C  CE3  . TRP A 1 52  ? 82.956  62.088  120.102 1.00 128.22 ? 52  TRP A CE3  1 
ATOM   299  C  CZ2  . TRP A 1 52  ? 83.411  59.300  120.000 1.00 128.22 ? 52  TRP A CZ2  1 
ATOM   300  C  CZ3  . TRP A 1 52  ? 82.974  61.403  118.902 1.00 128.22 ? 52  TRP A CZ3  1 
ATOM   301  C  CH2  . TRP A 1 52  ? 83.201  60.024  118.858 1.00 128.22 ? 52  TRP A CH2  1 
ATOM   302  N  N    . LEU A 1 53  ? 86.007  64.167  122.813 1.00 122.77 ? 53  LEU A N    1 
ATOM   303  C  CA   . LEU A 1 53  ? 87.396  64.055  122.387 1.00 122.77 ? 53  LEU A CA   1 
ATOM   304  C  C    . LEU A 1 53  ? 88.368  64.346  123.523 1.00 122.77 ? 53  LEU A C    1 
ATOM   305  O  O    . LEU A 1 53  ? 89.535  63.949  123.439 1.00 122.77 ? 53  LEU A O    1 
ATOM   306  C  CB   . LEU A 1 53  ? 87.685  64.972  121.194 1.00 122.77 ? 53  LEU A CB   1 
ATOM   307  C  CG   . LEU A 1 53  ? 87.289  64.485  119.792 1.00 122.77 ? 53  LEU A CG   1 
ATOM   308  C  CD1  . LEU A 1 53  ? 85.796  64.471  119.545 1.00 122.77 ? 53  LEU A CD1  1 
ATOM   309  C  CD2  . LEU A 1 53  ? 87.990  65.320  118.729 1.00 122.77 ? 53  LEU A CD2  1 
ATOM   310  N  N    . LEU A 1 54  ? 87.917  65.020  124.582 1.00 123.58 ? 54  LEU A N    1 
ATOM   311  C  CA   . LEU A 1 54  ? 88.845  65.394  125.639 1.00 123.58 ? 54  LEU A CA   1 
ATOM   312  C  C    . LEU A 1 54  ? 89.228  64.216  126.524 1.00 123.58 ? 54  LEU A C    1 
ATOM   313  O  O    . LEU A 1 54  ? 90.406  64.096  126.885 1.00 123.58 ? 54  LEU A O    1 
ATOM   314  C  CB   . LEU A 1 54  ? 88.258  66.538  126.475 1.00 123.58 ? 54  LEU A CB   1 
ATOM   315  C  CG   . LEU A 1 54  ? 89.121  67.226  127.541 1.00 123.58 ? 54  LEU A CG   1 
ATOM   316  C  CD1  . LEU A 1 54  ? 88.622  68.631  127.722 1.00 123.58 ? 54  LEU A CD1  1 
ATOM   317  C  CD2  . LEU A 1 54  ? 89.089  66.531  128.897 1.00 123.58 ? 54  LEU A CD2  1 
ATOM   318  N  N    . GLN A 1 55  ? 88.268  63.357  126.917 1.00 130.02 ? 55  GLN A N    1 
ATOM   319  C  CA   . GLN A 1 55  ? 88.611  62.449  128.027 1.00 130.02 ? 55  GLN A CA   1 
ATOM   320  C  C    . GLN A 1 55  ? 89.677  61.434  127.631 1.00 130.02 ? 55  GLN A C    1 
ATOM   321  O  O    . GLN A 1 55  ? 90.352  60.887  128.508 1.00 130.02 ? 55  GLN A O    1 
ATOM   322  C  CB   . GLN A 1 55  ? 87.458  61.602  128.592 1.00 130.02 ? 55  GLN A CB   1 
ATOM   323  C  CG   . GLN A 1 55  ? 86.329  62.332  129.325 1.00 130.02 ? 55  GLN A CG   1 
ATOM   324  C  CD   . GLN A 1 55  ? 85.229  61.453  129.774 1.00 130.02 ? 55  GLN A CD   1 
ATOM   325  O  OE1  . GLN A 1 55  ? 85.019  60.406  129.205 1.00 130.02 ? 55  GLN A OE1  1 
ATOM   326  N  NE2  . GLN A 1 55  ? 84.505  61.871  130.803 1.00 130.02 ? 55  GLN A NE2  1 
ATOM   327  N  N    . TRP A 1 56  ? 89.839  61.169  126.333 1.00 135.55 ? 56  TRP A N    1 
ATOM   328  C  CA   . TRP A 1 56  ? 90.825  60.199  125.882 1.00 135.55 ? 56  TRP A CA   1 
ATOM   329  C  C    . TRP A 1 56  ? 92.245  60.736  125.984 1.00 135.55 ? 56  TRP A C    1 
ATOM   330  O  O    . TRP A 1 56  ? 93.195  59.946  125.972 1.00 135.55 ? 56  TRP A O    1 
ATOM   331  C  CB   . TRP A 1 56  ? 90.526  59.786  124.440 1.00 135.55 ? 56  TRP A CB   1 
ATOM   332  C  CG   . TRP A 1 56  ? 89.392  58.817  124.310 1.00 135.55 ? 56  TRP A CG   1 
ATOM   333  C  CD1  . TRP A 1 56  ? 89.026  57.858  125.210 1.00 135.55 ? 56  TRP A CD1  1 
ATOM   334  C  CD2  . TRP A 1 56  ? 88.471  58.716  123.219 1.00 135.55 ? 56  TRP A CD2  1 
ATOM   335  N  NE1  . TRP A 1 56  ? 87.936  57.166  124.743 1.00 135.55 ? 56  TRP A NE1  1 
ATOM   336  C  CE2  . TRP A 1 56  ? 87.576  57.672  123.522 1.00 135.55 ? 56  TRP A CE2  1 
ATOM   337  C  CE3  . TRP A 1 56  ? 88.319  59.405  122.012 1.00 135.55 ? 56  TRP A CE3  1 
ATOM   338  C  CZ2  . TRP A 1 56  ? 86.543  57.302  122.666 1.00 135.55 ? 56  TRP A CZ2  1 
ATOM   339  C  CZ3  . TRP A 1 56  ? 87.294  59.036  121.162 1.00 135.55 ? 56  TRP A CZ3  1 
ATOM   340  C  CH2  . TRP A 1 56  ? 86.419  57.995  121.492 1.00 135.55 ? 56  TRP A CH2  1 
ATOM   341  N  N    . ILE A 1 57  ? 92.407  62.047  126.078 1.00 133.92 ? 57  ILE A N    1 
ATOM   342  C  CA   . ILE A 1 57  ? 93.739  62.650  126.148 1.00 133.92 ? 57  ILE A CA   1 
ATOM   343  C  C    . ILE A 1 57  ? 94.320  62.407  127.538 1.00 133.92 ? 57  ILE A C    1 
ATOM   344  O  O    . ILE A 1 57  ? 93.629  62.656  128.538 1.00 133.92 ? 57  ILE A O    1 
ATOM   345  C  CB   . ILE A 1 57  ? 93.671  64.136  125.829 1.00 133.92 ? 57  ILE A CB   1 
ATOM   346  C  CG1  . ILE A 1 57  ? 93.221  64.330  124.385 1.00 133.92 ? 57  ILE A CG1  1 
ATOM   347  C  CG2  . ILE A 1 57  ? 95.014  64.809  126.053 1.00 133.92 ? 57  ILE A CG2  1 
ATOM   348  C  CD1  . ILE A 1 57  ? 92.906  65.743  124.045 1.00 133.92 ? 57  ILE A CD1  1 
ATOM   349  N  N    . PRO A 1 58  ? 95.553  61.916  127.640 1.00 134.30 ? 58  PRO A N    1 
ATOM   350  C  CA   . PRO A 1 58  ? 96.165  61.717  128.958 1.00 134.30 ? 58  PRO A CA   1 
ATOM   351  C  C    . PRO A 1 58  ? 96.390  63.037  129.678 1.00 134.30 ? 58  PRO A C    1 
ATOM   352  O  O    . PRO A 1 58  ? 96.610  64.083  129.064 1.00 134.30 ? 58  PRO A O    1 
ATOM   353  C  CB   . PRO A 1 58  ? 97.493  61.027  128.631 1.00 134.30 ? 58  PRO A CB   1 
ATOM   354  C  CG   . PRO A 1 58  ? 97.776  61.400  127.214 1.00 134.30 ? 58  PRO A CG   1 
ATOM   355  C  CD   . PRO A 1 58  ? 96.440  61.481  126.547 1.00 134.30 ? 58  PRO A CD   1 
ATOM   356  N  N    . LEU A 1 59  ? 96.335  62.970  131.008 1.00 131.13 ? 59  LEU A N    1 
ATOM   357  C  CA   . LEU A 1 59  ? 96.358  64.170  131.833 1.00 131.13 ? 59  LEU A CA   1 
ATOM   358  C  C    . LEU A 1 59  ? 97.740  64.799  131.939 1.00 131.13 ? 59  LEU A C    1 
ATOM   359  O  O    . LEU A 1 59  ? 97.843  65.959  132.352 1.00 131.13 ? 59  LEU A O    1 
ATOM   360  C  CB   . LEU A 1 59  ? 95.835  63.854  133.234 1.00 131.13 ? 59  LEU A CB   1 
ATOM   361  C  CG   . LEU A 1 59  ? 94.564  63.007  133.322 1.00 131.13 ? 59  LEU A CG   1 
ATOM   362  C  CD1  . LEU A 1 59  ? 94.196  62.757  134.774 1.00 131.13 ? 59  LEU A CD1  1 
ATOM   363  C  CD2  . LEU A 1 59  ? 93.411  63.666  132.583 1.00 131.13 ? 59  LEU A CD2  1 
ATOM   364  N  N    . TRP A 1 60  ? 98.801  64.075  131.586 1.00 128.70 ? 60  TRP A N    1 
ATOM   365  C  CA   . TRP A 1 60  ? 100.145 64.618  131.723 1.00 128.70 ? 60  TRP A CA   1 
ATOM   366  C  C    . TRP A 1 60  ? 100.550 65.518  130.565 1.00 128.70 ? 60  TRP A C    1 
ATOM   367  O  O    . TRP A 1 60  ? 101.618 66.135  130.626 1.00 128.70 ? 60  TRP A O    1 
ATOM   368  C  CB   . TRP A 1 60  ? 101.163 63.487  131.873 1.00 128.70 ? 60  TRP A CB   1 
ATOM   369  C  CG   . TRP A 1 60  ? 101.038 62.404  130.848 1.00 128.70 ? 60  TRP A CG   1 
ATOM   370  C  CD1  . TRP A 1 60  ? 100.380 61.219  130.992 1.00 128.70 ? 60  TRP A CD1  1 
ATOM   371  C  CD2  . TRP A 1 60  ? 101.585 62.404  129.526 1.00 128.70 ? 60  TRP A CD2  1 
ATOM   372  N  NE1  . TRP A 1 60  ? 100.486 60.478  129.843 1.00 128.70 ? 60  TRP A NE1  1 
ATOM   373  C  CE2  . TRP A 1 60  ? 101.219 61.185  128.926 1.00 128.70 ? 60  TRP A CE2  1 
ATOM   374  C  CE3  . TRP A 1 60  ? 102.352 63.313  128.792 1.00 128.70 ? 60  TRP A CE3  1 
ATOM   375  C  CZ2  . TRP A 1 60  ? 101.589 60.853  127.625 1.00 128.70 ? 60  TRP A CZ2  1 
ATOM   376  C  CZ3  . TRP A 1 60  ? 102.716 62.982  127.504 1.00 128.70 ? 60  TRP A CZ3  1 
ATOM   377  C  CH2  . TRP A 1 60  ? 102.336 61.762  126.933 1.00 128.70 ? 60  TRP A CH2  1 
ATOM   378  N  N    . MET A 1 61  ? 99.736  65.608  129.517 1.00 118.28 ? 61  MET A N    1 
ATOM   379  C  CA   . MET A 1 61  ? 100.076 66.429  128.364 1.00 118.28 ? 61  MET A CA   1 
ATOM   380  C  C    . MET A 1 61  ? 99.884  67.902  128.696 1.00 118.28 ? 61  MET A C    1 
ATOM   381  O  O    . MET A 1 61  ? 98.843  68.298  129.227 1.00 118.28 ? 61  MET A O    1 
ATOM   382  C  CB   . MET A 1 61  ? 99.217  66.029  127.165 1.00 118.28 ? 61  MET A CB   1 
ATOM   383  C  CG   . MET A 1 61  ? 99.669  66.616  125.843 1.00 118.28 ? 61  MET A CG   1 
ATOM   384  S  SD   . MET A 1 61  ? 98.893  65.796  124.435 1.00 118.28 ? 61  MET A SD   1 
ATOM   385  C  CE   . MET A 1 61  ? 99.152  67.012  123.146 1.00 118.28 ? 61  MET A CE   1 
ATOM   386  N  N    . ALA A 1 62  ? 100.895 68.710  128.391 1.00 105.61 ? 62  ALA A N    1 
ATOM   387  C  CA   . ALA A 1 62  ? 100.832 70.131  128.681 1.00 105.61 ? 62  ALA A CA   1 
ATOM   388  C  C    . ALA A 1 62  ? 99.843  70.822  127.742 1.00 105.61 ? 62  ALA A C    1 
ATOM   389  O  O    . ALA A 1 62  ? 99.686  70.415  126.591 1.00 105.61 ? 62  ALA A O    1 
ATOM   390  C  CB   . ALA A 1 62  ? 102.212 70.763  128.539 1.00 105.61 ? 62  ALA A CB   1 
ATOM   391  N  N    . PRO A 1 63  ? 99.156  71.866  128.217 1.00 99.15  ? 63  PRO A N    1 
ATOM   392  C  CA   . PRO A 1 63  ? 98.205  72.556  127.332 1.00 99.15  ? 63  PRO A CA   1 
ATOM   393  C  C    . PRO A 1 63  ? 98.876  73.259  126.168 1.00 99.15  ? 63  PRO A C    1 
ATOM   394  O  O    . PRO A 1 63  ? 98.367  73.212  125.038 1.00 99.15  ? 63  PRO A O    1 
ATOM   395  C  CB   . PRO A 1 63  ? 97.517  73.549  128.276 1.00 99.15  ? 63  PRO A CB   1 
ATOM   396  C  CG   . PRO A 1 63  ? 98.495  73.764  129.372 1.00 99.15  ? 63  PRO A CG   1 
ATOM   397  C  CD   . PRO A 1 63  ? 99.182  72.451  129.565 1.00 99.15  ? 63  PRO A CD   1 
ATOM   398  N  N    . ASN A 1 64  ? 100.023 73.892  126.409 1.00 99.06  ? 64  ASN A N    1 
ATOM   399  C  CA   . ASN A 1 64  ? 100.725 74.577  125.333 1.00 99.06  ? 64  ASN A CA   1 
ATOM   400  C  C    . ASN A 1 64  ? 101.185 73.610  124.255 1.00 99.06  ? 64  ASN A C    1 
ATOM   401  O  O    . ASN A 1 64  ? 101.288 73.994  123.086 1.00 99.06  ? 64  ASN A O    1 
ATOM   402  C  CB   . ASN A 1 64  ? 101.901 75.359  125.903 1.00 99.06  ? 64  ASN A CB   1 
ATOM   403  C  CG   . ASN A 1 64  ? 101.530 76.115  127.155 1.00 99.06  ? 64  ASN A CG   1 
ATOM   404  O  OD1  . ASN A 1 64  ? 100.661 76.984  127.131 1.00 99.06  ? 64  ASN A OD1  1 
ATOM   405  N  ND2  . ASN A 1 64  ? 102.183 75.786  128.260 1.00 99.06  ? 64  ASN A ND2  1 
ATOM   406  N  N    . SER A 1 65  ? 101.445 72.352  124.620 1.00 100.92 ? 65  SER A N    1 
ATOM   407  C  CA   . SER A 1 65  ? 101.734 71.339  123.610 1.00 100.92 ? 65  SER A CA   1 
ATOM   408  C  C    . SER A 1 65  ? 100.540 71.134  122.689 1.00 100.92 ? 65  SER A C    1 
ATOM   409  O  O    . SER A 1 65  ? 100.704 70.987  121.474 1.00 100.92 ? 65  SER A O    1 
ATOM   410  C  CB   . SER A 1 65  ? 102.124 70.024  124.281 1.00 100.92 ? 65  SER A CB   1 
ATOM   411  O  OG   . SER A 1 65  ? 101.029 69.486  125.000 1.00 100.92 ? 65  SER A OG   1 
ATOM   412  N  N    . ILE A 1 66  ? 99.331  71.142  123.251 1.00 96.88  ? 66  ILE A N    1 
ATOM   413  C  CA   . ILE A 1 66  ? 98.126  71.033  122.440 1.00 96.88  ? 66  ILE A CA   1 
ATOM   414  C  C    . ILE A 1 66  ? 98.001  72.227  121.501 1.00 96.88  ? 66  ILE A C    1 
ATOM   415  O  O    . ILE A 1 66  ? 97.714  72.071  120.303 1.00 96.88  ? 66  ILE A O    1 
ATOM   416  C  CB   . ILE A 1 66  ? 96.889  70.903  123.345 1.00 96.88  ? 66  ILE A CB   1 
ATOM   417  C  CG1  . ILE A 1 66  ? 97.128  69.873  124.452 1.00 96.88  ? 66  ILE A CG1  1 
ATOM   418  C  CG2  . ILE A 1 66  ? 95.667  70.552  122.526 1.00 96.88  ? 66  ILE A CG2  1 
ATOM   419  C  CD1  . ILE A 1 66  ? 96.041  69.861  125.506 1.00 96.88  ? 66  ILE A CD1  1 
ATOM   420  N  N    . THR A 1 67  ? 98.220  73.437  122.031 1.00 89.12  ? 67  THR A N    1 
ATOM   421  C  CA   . THR A 1 67  ? 98.139  74.640  121.201 1.00 89.12  ? 67  THR A CA   1 
ATOM   422  C  C    . THR A 1 67  ? 99.132  74.576  120.054 1.00 89.12  ? 67  THR A C    1 
ATOM   423  O  O    . THR A 1 67  ? 98.790  74.853  118.897 1.00 89.12  ? 67  THR A O    1 
ATOM   424  C  CB   . THR A 1 67  ? 98.438  75.884  122.028 1.00 89.12  ? 67  THR A CB   1 
ATOM   425  O  OG1  . THR A 1 67  ? 99.847  75.944  122.239 1.00 89.12  ? 67  THR A OG1  1 
ATOM   426  C  CG2  . THR A 1 67  ? 97.806  75.798  123.371 1.00 89.12  ? 67  THR A CG2  1 
ATOM   427  N  N    . LEU A 1 68  ? 100.373 74.203  120.364 1.00 85.67  ? 68  LEU A N    1 
ATOM   428  C  CA   . LEU A 1 68  ? 101.425 74.153  119.361 1.00 85.67  ? 68  LEU A CA   1 
ATOM   429  C  C    . LEU A 1 68  ? 101.142 73.083  118.321 1.00 85.67  ? 68  LEU A C    1 
ATOM   430  O  O    . LEU A 1 68  ? 101.412 73.289  117.135 1.00 85.67  ? 68  LEU A O    1 
ATOM   431  C  CB   . LEU A 1 68  ? 102.773 73.910  120.033 1.00 85.67  ? 68  LEU A CB   1 
ATOM   432  C  CG   . LEU A 1 68  ? 103.999 73.906  119.122 1.00 85.67  ? 68  LEU A CG   1 
ATOM   433  C  CD1  . LEU A 1 68  ? 104.411 75.328  118.856 1.00 85.67  ? 68  LEU A CD1  1 
ATOM   434  C  CD2  . LEU A 1 68  ? 105.145 73.135  119.755 1.00 85.67  ? 68  LEU A CD2  1 
ATOM   435  N  N    . LEU A 1 69  ? 100.602 71.938  118.738 1.00 84.27  ? 69  LEU A N    1 
ATOM   436  C  CA   . LEU A 1 69  ? 100.280 70.888  117.778 1.00 84.27  ? 69  LEU A CA   1 
ATOM   437  C  C    . LEU A 1 69  ? 99.212  71.359  116.803 1.00 84.27  ? 69  LEU A C    1 
ATOM   438  O  O    . LEU A 1 69  ? 99.337  71.163  115.586 1.00 84.27  ? 69  LEU A O    1 
ATOM   439  C  CB   . LEU A 1 69  ? 99.821  69.630  118.506 1.00 84.27  ? 69  LEU A CB   1 
ATOM   440  C  CG   . LEU A 1 69  ? 99.244  68.537  117.608 1.00 84.27  ? 69  LEU A CG   1 
ATOM   441  C  CD1  . LEU A 1 69  ? 100.312 67.989  116.670 1.00 84.27  ? 69  LEU A CD1  1 
ATOM   442  C  CD2  . LEU A 1 69  ? 98.639  67.434  118.448 1.00 84.27  ? 69  LEU A CD2  1 
ATOM   443  N  N    . GLY A 1 70  ? 98.166  72.007  117.320 1.00 79.87  ? 70  GLY A N    1 
ATOM   444  C  CA   . GLY A 1 70  ? 97.135  72.530  116.438 1.00 79.87  ? 70  GLY A CA   1 
ATOM   445  C  C    . GLY A 1 70  ? 97.668  73.570  115.470 1.00 79.87  ? 70  GLY A C    1 
ATOM   446  O  O    . GLY A 1 70  ? 97.399  73.510  114.263 1.00 79.87  ? 70  GLY A O    1 
ATOM   447  N  N    . LEU A 1 71  ? 98.457  74.518  115.982 1.00 71.65  ? 71  LEU A N    1 
ATOM   448  C  CA   . LEU A 1 71  ? 99.015  75.557  115.126 1.00 71.65  ? 71  LEU A CA   1 
ATOM   449  C  C    . LEU A 1 71  ? 99.943  74.971  114.075 1.00 71.65  ? 71  LEU A C    1 
ATOM   450  O  O    . LEU A 1 71  ? 99.928  75.402  112.919 1.00 71.65  ? 71  LEU A O    1 
ATOM   451  C  CB   . LEU A 1 71  ? 99.759  76.594  115.960 1.00 71.65  ? 71  LEU A CB   1 
ATOM   452  C  CG   . LEU A 1 71  ? 100.208 77.808  115.153 1.00 71.65  ? 71  LEU A CG   1 
ATOM   453  C  CD1  . LEU A 1 71  ? 99.076  78.352  114.312 1.00 71.65  ? 71  LEU A CD1  1 
ATOM   454  C  CD2  . LEU A 1 71  ? 100.764 78.883  116.055 1.00 71.65  ? 71  LEU A CD2  1 
ATOM   455  N  N    . ALA A 1 72  ? 100.760 73.988  114.456 1.00 72.18  ? 72  ALA A N    1 
ATOM   456  C  CA   . ALA A 1 72  ? 101.684 73.380  113.509 1.00 72.18  ? 72  ALA A CA   1 
ATOM   457  C  C    . ALA A 1 72  ? 100.937 72.651  112.406 1.00 72.18  ? 72  ALA A C    1 
ATOM   458  O  O    . ALA A 1 72  ? 101.303 72.758  111.230 1.00 72.18  ? 72  ALA A O    1 
ATOM   459  C  CB   . ALA A 1 72  ? 102.633 72.428  114.235 1.00 72.18  ? 72  ALA A CB   1 
ATOM   460  N  N    . VAL A 1 73  ? 99.881  71.914  112.762 1.00 69.80  ? 73  VAL A N    1 
ATOM   461  C  CA   . VAL A 1 73  ? 99.116  71.200  111.746 1.00 69.80  ? 73  VAL A CA   1 
ATOM   462  C  C    . VAL A 1 73  ? 98.470  72.180  110.777 1.00 69.80  ? 73  VAL A C    1 
ATOM   463  O  O    . VAL A 1 73  ? 98.548  72.005  109.549 1.00 69.80  ? 73  VAL A O    1 
ATOM   464  C  CB   . VAL A 1 73  ? 98.077  70.280  112.410 1.00 69.80  ? 73  VAL A CB   1 
ATOM   465  C  CG1  . VAL A 1 73  ? 97.090  69.772  111.386 1.00 69.80  ? 73  VAL A CG1  1 
ATOM   466  C  CG2  . VAL A 1 73  ? 98.774  69.111  113.076 1.00 69.80  ? 73  VAL A CG2  1 
ATOM   467  N  N    . ASN A 1 74  ? 97.858  73.243  111.308 1.00 68.15  ? 74  ASN A N    1 
ATOM   468  C  CA   . ASN A 1 74  ? 97.210  74.214  110.430 1.00 68.15  ? 74  ASN A CA   1 
ATOM   469  C  C    . ASN A 1 74  ? 98.215  74.926  109.536 1.00 68.15  ? 74  ASN A C    1 
ATOM   470  O  O    . ASN A 1 74  ? 97.974  75.099  108.334 1.00 68.15  ? 74  ASN A O    1 
ATOM   471  C  CB   . ASN A 1 74  ? 96.428  75.234  111.248 1.00 68.15  ? 74  ASN A CB   1 
ATOM   472  C  CG   . ASN A 1 74  ? 95.761  76.270  110.382 1.00 68.15  ? 74  ASN A CG   1 
ATOM   473  O  OD1  . ASN A 1 74  ? 94.727  76.013  109.768 1.00 68.15  ? 74  ASN A OD1  1 
ATOM   474  N  ND2  . ASN A 1 74  ? 96.358  77.449  110.311 1.00 68.15  ? 74  ASN A ND2  1 
ATOM   475  N  N    . VAL A 1 75  ? 99.354  75.334  110.101 1.00 64.96  ? 75  VAL A N    1 
ATOM   476  C  CA   . VAL A 1 75  ? 100.360 76.043  109.324 1.00 64.96  ? 75  VAL A CA   1 
ATOM   477  C  C    . VAL A 1 75  ? 100.933 75.151  108.233 1.00 64.96  ? 75  VAL A C    1 
ATOM   478  O  O    . VAL A 1 75  ? 101.098 75.587  107.092 1.00 64.96  ? 75  VAL A O    1 
ATOM   479  C  CB   . VAL A 1 75  ? 101.459 76.591  110.252 1.00 64.96  ? 75  VAL A CB   1 
ATOM   480  C  CG1  . VAL A 1 75  ? 102.717 76.914  109.472 1.00 64.96  ? 75  VAL A CG1  1 
ATOM   481  C  CG2  . VAL A 1 75  ? 100.963 77.833  110.955 1.00 64.96  ? 75  VAL A CG2  1 
ATOM   482  N  N    . VAL A 1 76  ? 101.216 73.886  108.550 1.00 66.56  ? 76  VAL A N    1 
ATOM   483  C  CA   . VAL A 1 76  ? 101.795 72.990  107.553 1.00 66.56  ? 76  VAL A CA   1 
ATOM   484  C  C    . VAL A 1 76  ? 100.810 72.740  106.414 1.00 66.56  ? 76  VAL A C    1 
ATOM   485  O  O    . VAL A 1 76  ? 101.177 72.812  105.232 1.00 66.56  ? 76  VAL A O    1 
ATOM   486  C  CB   . VAL A 1 76  ? 102.252 71.678  108.215 1.00 66.56  ? 76  VAL A CB   1 
ATOM   487  C  CG1  . VAL A 1 76  ? 102.362 70.561  107.192 1.00 66.56  ? 76  VAL A CG1  1 
ATOM   488  C  CG2  . VAL A 1 76  ? 103.584 71.882  108.909 1.00 66.56  ? 76  VAL A CG2  1 
ATOM   489  N  N    . THR A 1 77  ? 99.542  72.465  106.743 1.00 65.34  ? 77  THR A N    1 
ATOM   490  C  CA   . THR A 1 77  ? 98.573  72.199  105.682 1.00 65.34  ? 77  THR A CA   1 
ATOM   491  C  C    . THR A 1 77  ? 98.337  73.430  104.816 1.00 65.34  ? 77  THR A C    1 
ATOM   492  O  O    . THR A 1 77  ? 98.294  73.328  103.581 1.00 65.34  ? 77  THR A O    1 
ATOM   493  C  CB   . THR A 1 77  ? 97.256  71.707  106.271 1.00 65.34  ? 77  THR A CB   1 
ATOM   494  O  OG1  . THR A 1 77  ? 96.821  72.617  107.283 1.00 65.34  ? 77  THR A OG1  1 
ATOM   495  C  CG2  . THR A 1 77  ? 97.440  70.332  106.875 1.00 65.34  ? 77  THR A CG2  1 
ATOM   496  N  N    . THR A 1 78  ? 98.204  74.605  105.432 1.00 60.86  ? 78  THR A N    1 
ATOM   497  C  CA   . THR A 1 78  ? 97.998  75.805  104.635 1.00 60.86  ? 78  THR A CA   1 
ATOM   498  C  C    . THR A 1 78  ? 99.242  76.165  103.833 1.00 60.86  ? 78  THR A C    1 
ATOM   499  O  O    . THR A 1 78  ? 99.125  76.707  102.732 1.00 60.86  ? 78  THR A O    1 
ATOM   500  C  CB   . THR A 1 78  ? 97.577  76.966  105.525 1.00 60.86  ? 78  THR A CB   1 
ATOM   501  O  OG1  . THR A 1 78  ? 96.596  76.504  106.458 1.00 60.86  ? 78  THR A OG1  1 
ATOM   502  C  CG2  . THR A 1 78  ? 96.966  78.066  104.694 1.00 60.86  ? 78  THR A CG2  1 
ATOM   503  N  N    . LEU A 1 79  ? 100.434 75.848  104.340 1.00 62.74  ? 79  LEU A N    1 
ATOM   504  C  CA   . LEU A 1 79  ? 101.640 76.101  103.561 1.00 62.74  ? 79  LEU A CA   1 
ATOM   505  C  C    . LEU A 1 79  ? 101.715 75.186  102.349 1.00 62.74  ? 79  LEU A C    1 
ATOM   506  O  O    . LEU A 1 79  ? 102.147 75.611  101.275 1.00 62.74  ? 79  LEU A O    1 
ATOM   507  C  CB   . LEU A 1 79  ? 102.881 75.938  104.429 1.00 62.74  ? 79  LEU A CB   1 
ATOM   508  C  CG   . LEU A 1 79  ? 103.303 77.160  105.242 1.00 62.74  ? 79  LEU A CG   1 
ATOM   509  C  CD1  . LEU A 1 79  ? 104.708 76.964  105.776 1.00 62.74  ? 79  LEU A CD1  1 
ATOM   510  C  CD2  . LEU A 1 79  ? 103.211 78.424  104.411 1.00 62.74  ? 79  LEU A CD2  1 
ATOM   511  N  N    . VAL A 1 80  ? 101.297 73.927  102.497 1.00 63.63  ? 80  VAL A N    1 
ATOM   512  C  CA   . VAL A 1 80  ? 101.267 73.027  101.344 1.00 63.63  ? 80  VAL A CA   1 
ATOM   513  C  C    . VAL A 1 80  ? 100.265 73.524  100.308 1.00 63.63  ? 80  VAL A C    1 
ATOM   514  O  O    . VAL A 1 80  ? 100.559 73.567  99.103  1.00 63.63  ? 80  VAL A O    1 
ATOM   515  C  CB   . VAL A 1 80  ? 100.959 71.589  101.797 1.00 63.63  ? 80  VAL A CB   1 
ATOM   516  C  CG1  . VAL A 1 80  ? 100.490 70.748  100.631 1.00 63.63  ? 80  VAL A CG1  1 
ATOM   517  C  CG2  . VAL A 1 80  ? 102.193 70.965  102.418 1.00 63.63  ? 80  VAL A CG2  1 
ATOM   518  N  N    . LEU A 1 81  ? 99.081  73.934  100.764 1.00 61.62  ? 81  LEU A N    1 
ATOM   519  C  CA   . LEU A 1 81  ? 98.092  74.472  99.836  1.00 61.62  ? 81  LEU A CA   1 
ATOM   520  C  C    . LEU A 1 81  ? 98.580  75.749  99.163  1.00 61.62  ? 81  LEU A C    1 
ATOM   521  O  O    . LEU A 1 81  ? 98.254  75.994  98.000  1.00 61.62  ? 81  LEU A O    1 
ATOM   522  C  CB   . LEU A 1 81  ? 96.780  74.730  100.565 1.00 61.62  ? 81  LEU A CB   1 
ATOM   523  C  CG   . LEU A 1 81  ? 95.546  74.975  99.711  1.00 61.62  ? 81  LEU A CG   1 
ATOM   524  C  CD1  . LEU A 1 81  ? 94.385  74.345  100.414 1.00 61.62  ? 81  LEU A CD1  1 
ATOM   525  C  CD2  . LEU A 1 81  ? 95.293  76.446  99.543  1.00 61.62  ? 81  LEU A CD2  1 
ATOM   526  N  N    . ILE A 1 82  ? 99.342  76.579  99.875  1.00 61.08  ? 82  ILE A N    1 
ATOM   527  C  CA   . ILE A 1 82  ? 99.940  77.757  99.257  1.00 61.08  ? 82  ILE A CA   1 
ATOM   528  C  C    . ILE A 1 82  ? 100.993 77.337  98.237  1.00 61.08  ? 82  ILE A C    1 
ATOM   529  O  O    . ILE A 1 82  ? 101.123 77.950  97.172  1.00 61.08  ? 82  ILE A O    1 
ATOM   530  C  CB   . ILE A 1 82  ? 100.522 78.679  100.344 1.00 61.08  ? 82  ILE A CB   1 
ATOM   531  C  CG1  . ILE A 1 82  ? 99.408  79.447  101.037 1.00 61.08  ? 82  ILE A CG1  1 
ATOM   532  C  CG2  . ILE A 1 82  ? 101.499 79.671  99.766  1.00 61.08  ? 82  ILE A CG2  1 
ATOM   533  C  CD1  . ILE A 1 82  ? 99.807  80.007  102.368 1.00 61.08  ? 82  ILE A CD1  1 
ATOM   534  N  N    . SER A 1 83  ? 101.732 76.269  98.536  1.00 64.22  ? 83  SER A N    1 
ATOM   535  C  CA   . SER A 1 83  ? 102.756 75.784  97.618  1.00 64.22  ? 83  SER A CA   1 
ATOM   536  C  C    . SER A 1 83  ? 102.150 75.346  96.296  1.00 64.22  ? 83  SER A C    1 
ATOM   537  O  O    . SER A 1 83  ? 102.716 75.615  95.231  1.00 64.22  ? 83  SER A O    1 
ATOM   538  C  CB   . SER A 1 83  ? 103.526 74.629  98.255  1.00 64.22  ? 83  SER A CB   1 
ATOM   539  O  OG   . SER A 1 83  ? 104.275 73.925  97.281  1.00 64.22  ? 83  SER A OG   1 
ATOM   540  N  N    . TYR A 1 84  ? 101.004 74.675  96.333  1.00 70.91  ? 84  TYR A N    1 
ATOM   541  C  CA   . TYR A 1 84  ? 100.414 74.289  95.058  1.00 70.91  ? 84  TYR A CA   1 
ATOM   542  C  C    . TYR A 1 84  ? 99.631  75.406  94.386  1.00 70.91  ? 84  TYR A C    1 
ATOM   543  O  O    . TYR A 1 84  ? 99.235  75.240  93.231  1.00 70.91  ? 84  TYR A O    1 
ATOM   544  C  CB   . TYR A 1 84  ? 99.521  73.062  95.219  1.00 70.91  ? 84  TYR A CB   1 
ATOM   545  C  CG   . TYR A 1 84  ? 100.288 71.770  95.115  1.00 70.91  ? 84  TYR A CG   1 
ATOM   546  C  CD1  . TYR A 1 84  ? 101.676 71.763  95.139  1.00 70.91  ? 84  TYR A CD1  1 
ATOM   547  C  CD2  . TYR A 1 84  ? 99.631  70.560  94.974  1.00 70.91  ? 84  TYR A CD2  1 
ATOM   548  C  CE1  . TYR A 1 84  ? 102.388 70.587  95.039  1.00 70.91  ? 84  TYR A CE1  1 
ATOM   549  C  CE2  . TYR A 1 84  ? 100.334 69.376  94.874  1.00 70.91  ? 84  TYR A CE2  1 
ATOM   550  C  CZ   . TYR A 1 84  ? 101.714 69.397  94.908  1.00 70.91  ? 84  TYR A CZ   1 
ATOM   551  O  OH   . TYR A 1 84  ? 102.422 68.219  94.806  1.00 70.91  ? 84  TYR A OH   1 
ATOM   552  N  N    . CYS A 1 85  ? 99.417  76.535  95.054  1.00 71.61  ? 85  CYS A N    1 
ATOM   553  C  CA   . CYS A 1 85  ? 98.722  77.677  94.454  1.00 71.61  ? 85  CYS A CA   1 
ATOM   554  C  C    . CYS A 1 85  ? 99.268  78.968  95.035  1.00 71.61  ? 85  CYS A C    1 
ATOM   555  O  O    . CYS A 1 85  ? 98.656  79.582  95.915  1.00 71.61  ? 85  CYS A O    1 
ATOM   556  C  CB   . CYS A 1 85  ? 97.209  77.599  94.671  1.00 71.61  ? 85  CYS A CB   1 
ATOM   557  S  SG   . CYS A 1 85  ? 96.343  76.245  93.859  1.00 71.61  ? 85  CYS A SG   1 
ATOM   558  N  N    . PRO A 1 86  ? 100.440 79.410  94.575  1.00 65.96  ? 86  PRO A N    1 
ATOM   559  C  CA   . PRO A 1 86  ? 100.976 80.685  95.066  1.00 65.96  ? 86  PRO A CA   1 
ATOM   560  C  C    . PRO A 1 86  ? 100.095 81.868  94.734  1.00 65.96  ? 86  PRO A C    1 
ATOM   561  O  O    . PRO A 1 86  ? 100.026 82.816  95.520  1.00 65.96  ? 86  PRO A O    1 
ATOM   562  C  CB   . PRO A 1 86  ? 102.339 80.778  94.373  1.00 65.96  ? 86  PRO A CB   1 
ATOM   563  C  CG   . PRO A 1 86  ? 102.175 79.984  93.135  1.00 65.96  ? 86  PRO A CG   1 
ATOM   564  C  CD   . PRO A 1 86  ? 101.252 78.853  93.481  1.00 65.96  ? 86  PRO A CD   1 
ATOM   565  N  N    . THR A 1 87  ? 99.426  81.842  93.593  1.00 74.93  ? 87  THR A N    1 
ATOM   566  C  CA   . THR A 1 87  ? 98.430  82.836  93.255  1.00 74.93  ? 87  THR A CA   1 
ATOM   567  C  C    . THR A 1 87  ? 97.063  82.294  93.637  1.00 74.93  ? 87  THR A C    1 
ATOM   568  O  O    . THR A 1 87  ? 96.943  81.269  94.309  1.00 74.93  ? 87  THR A O    1 
ATOM   569  C  CB   . THR A 1 87  ? 98.494  83.190  91.773  1.00 74.93  ? 87  THR A CB   1 
ATOM   570  O  OG1  . THR A 1 87  ? 98.222  82.022  90.994  1.00 74.93  ? 87  THR A OG1  1 
ATOM   571  C  CG2  . THR A 1 87  ? 99.874  83.709  91.411  1.00 74.93  ? 87  THR A CG2  1 
ATOM   572  N  N    . ALA A 1 88  ? 96.013  82.976  93.197  1.00 80.77  ? 88  ALA A N    1 
ATOM   573  C  CA   . ALA A 1 88  ? 94.665  82.567  93.556  1.00 80.77  ? 88  ALA A CA   1 
ATOM   574  C  C    . ALA A 1 88  ? 93.769  82.444  92.330  1.00 80.77  ? 88  ALA A C    1 
ATOM   575  O  O    . ALA A 1 88  ? 92.556  82.641  92.423  1.00 80.77  ? 88  ALA A O    1 
ATOM   576  C  CB   . ALA A 1 88  ? 94.065  83.540  94.567  1.00 80.77  ? 88  ALA A CB   1 
ATOM   577  N  N    . THR A 1 89  ? 94.343  82.113  91.174  1.00 84.92  ? 89  THR A N    1 
ATOM   578  C  CA   . THR A 1 89  ? 93.568  81.966  89.946  1.00 84.92  ? 89  THR A CA   1 
ATOM   579  C  C    . THR A 1 89  ? 93.636  80.557  89.372  1.00 84.92  ? 89  THR A C    1 
ATOM   580  O  O    . THR A 1 89  ? 93.342  80.369  88.187  1.00 84.92  ? 89  THR A O    1 
ATOM   581  C  CB   . THR A 1 89  ? 94.033  82.969  88.888  1.00 84.92  ? 89  THR A CB   1 
ATOM   582  O  OG1  . THR A 1 89  ? 95.387  82.683  88.516  1.00 84.92  ? 89  THR A OG1  1 
ATOM   583  C  CG2  . THR A 1 89  ? 93.942  84.386  89.416  1.00 84.92  ? 89  THR A CG2  1 
ATOM   584  N  N    . GLU A 1 90  ? 94.022  79.571  90.171  1.00 85.55  ? 90  GLU A N    1 
ATOM   585  C  CA   . GLU A 1 90  ? 94.210  78.208  89.698  1.00 85.55  ? 90  GLU A CA   1 
ATOM   586  C  C    . GLU A 1 90  ? 93.828  77.227  90.792  1.00 85.55  ? 90  GLU A C    1 
ATOM   587  O  O    . GLU A 1 90  ? 93.834  77.555  91.980  1.00 85.55  ? 90  GLU A O    1 
ATOM   588  C  CB   . GLU A 1 90  ? 95.655  77.965  89.241  1.00 85.55  ? 90  GLU A CB   1 
ATOM   589  C  CG   . GLU A 1 90  ? 96.681  77.953  90.360  1.00 85.55  ? 90  GLU A CG   1 
ATOM   590  C  CD   . GLU A 1 90  ? 96.897  79.329  90.955  1.00 85.55  ? 90  GLU A CD   1 
ATOM   591  O  OE1  . GLU A 1 90  ? 96.590  80.325  90.271  1.00 85.55  ? 90  GLU A OE1  1 
ATOM   592  O  OE2  . GLU A 1 90  ? 97.367  79.433  92.101  1.00 85.55  ? 90  GLU A OE2  1 
ATOM   593  N  N    . GLU A 1 91  ? 93.507  76.006  90.374  1.00 96.90  ? 91  GLU A N    1 
ATOM   594  C  CA   . GLU A 1 91  ? 92.959  74.997  91.269  1.00 96.90  ? 91  GLU A CA   1 
ATOM   595  C  C    . GLU A 1 91  ? 94.034  73.996  91.670  1.00 96.90  ? 91  GLU A C    1 
ATOM   596  O  O    . GLU A 1 91  ? 94.749  73.462  90.818  1.00 96.90  ? 91  GLU A O    1 
ATOM   597  C  CB   . GLU A 1 91  ? 91.780  74.267  90.622  1.00 96.90  ? 91  GLU A CB   1 
ATOM   598  C  CG   . GLU A 1 91  ? 92.005  73.831  89.184  1.00 96.90  ? 91  GLU A CG   1 
ATOM   599  C  CD   . GLU A 1 91  ? 90.999  72.789  88.737  1.00 96.90  ? 91  GLU A CD   1 
ATOM   600  O  OE1  . GLU A 1 91  ? 90.171  72.367  89.572  1.00 96.90  ? 91  GLU A OE1  1 
ATOM   601  O  OE2  . GLU A 1 91  ? 91.038  72.385  87.556  1.00 96.90  ? 91  GLU A OE2  1 
ATOM   602  N  N    . ALA A 1 92  ? 94.150  73.765  92.968  1.00 94.71  ? 92  ALA A N    1 
ATOM   603  C  CA   . ALA A 1 92  ? 94.953  72.682  93.499  1.00 94.71  ? 92  ALA A CA   1 
ATOM   604  C  C    . ALA A 1 92  ? 94.152  71.387  93.460  1.00 94.71  ? 92  ALA A C    1 
ATOM   605  O  O    . ALA A 1 92  ? 92.928  71.413  93.305  1.00 94.71  ? 92  ALA A O    1 
ATOM   606  C  CB   . ALA A 1 92  ? 95.377  73.004  94.929  1.00 94.71  ? 92  ALA A CB   1 
ATOM   607  N  N    . PRO A 1 93  ? 94.815  70.235  93.565  1.00 98.41  ? 93  PRO A N    1 
ATOM   608  C  CA   . PRO A 1 93  ? 94.070  68.974  93.666  1.00 98.41  ? 93  PRO A CA   1 
ATOM   609  C  C    . PRO A 1 93  ? 93.212  68.930  94.924  1.00 98.41  ? 93  PRO A C    1 
ATOM   610  O  O    . PRO A 1 93  ? 93.510  69.577  95.928  1.00 98.41  ? 93  PRO A O    1 
ATOM   611  C  CB   . PRO A 1 93  ? 95.176  67.914  93.698  1.00 98.41  ? 93  PRO A CB   1 
ATOM   612  C  CG   . PRO A 1 93  ? 96.316  68.551  92.986  1.00 98.41  ? 93  PRO A CG   1 
ATOM   613  C  CD   . PRO A 1 93  ? 96.253  70.005  93.334  1.00 98.41  ? 93  PRO A CD   1 
ATOM   614  N  N    . TYR A 1 94  ? 92.119  68.166  94.851  1.00 97.66  ? 94  TYR A N    1 
ATOM   615  C  CA   . TYR A 1 94  ? 91.121  68.169  95.918  1.00 97.66  ? 94  TYR A CA   1 
ATOM   616  C  C    . TYR A 1 94  ? 91.635  67.577  97.224  1.00 97.66  ? 94  TYR A C    1 
ATOM   617  O  O    . TYR A 1 94  ? 91.088  67.894  98.292  1.00 97.66  ? 94  TYR A O    1 
ATOM   618  C  CB   . TYR A 1 94  ? 89.877  67.402  95.475  1.00 97.66  ? 94  TYR A CB   1 
ATOM   619  C  CG   . TYR A 1 94  ? 90.031  65.901  95.542  1.00 97.66  ? 94  TYR A CG   1 
ATOM   620  C  CD1  . TYR A 1 94  ? 90.857  65.226  94.650  1.00 97.66  ? 94  TYR A CD1  1 
ATOM   621  C  CD2  . TYR A 1 94  ? 89.344  65.156  96.489  1.00 97.66  ? 94  TYR A CD2  1 
ATOM   622  C  CE1  . TYR A 1 94  ? 90.998  63.855  94.708  1.00 97.66  ? 94  TYR A CE1  1 
ATOM   623  C  CE2  . TYR A 1 94  ? 89.477  63.783  96.551  1.00 97.66  ? 94  TYR A CE2  1 
ATOM   624  C  CZ   . TYR A 1 94  ? 90.308  63.140  95.658  1.00 97.66  ? 94  TYR A CZ   1 
ATOM   625  O  OH   . TYR A 1 94  ? 90.447  61.773  95.715  1.00 97.66  ? 94  TYR A OH   1 
ATOM   626  N  N    . TRP A 1 95  ? 92.664  66.727  97.168  1.00 91.50  ? 95  TRP A N    1 
ATOM   627  C  CA   . TRP A 1 95  ? 93.153  66.094  98.387  1.00 91.50  ? 95  TRP A CA   1 
ATOM   628  C  C    . TRP A 1 95  ? 93.751  67.120  99.341  1.00 91.50  ? 95  TRP A C    1 
ATOM   629  O  O    . TRP A 1 95  ? 93.586  67.003  100.560 1.00 91.50  ? 95  TRP A O    1 
ATOM   630  C  CB   . TRP A 1 95  ? 94.166  64.999  98.049  1.00 91.50  ? 95  TRP A CB   1 
ATOM   631  C  CG   . TRP A 1 95  ? 95.472  65.506  97.564  1.00 91.50  ? 95  TRP A CG   1 
ATOM   632  C  CD1  . TRP A 1 95  ? 95.818  65.756  96.275  1.00 91.50  ? 95  TRP A CD1  1 
ATOM   633  C  CD2  . TRP A 1 95  ? 96.620  65.816  98.357  1.00 91.50  ? 95  TRP A CD2  1 
ATOM   634  N  NE1  . TRP A 1 95  ? 97.109  66.212  96.212  1.00 91.50  ? 95  TRP A NE1  1 
ATOM   635  C  CE2  . TRP A 1 95  ? 97.625  66.257  97.480  1.00 91.50  ? 95  TRP A CE2  1 
ATOM   636  C  CE3  . TRP A 1 95  ? 96.895  65.766  99.724  1.00 91.50  ? 95  TRP A CE3  1 
ATOM   637  C  CZ2  . TRP A 1 95  ? 98.883  66.647  97.925  1.00 91.50  ? 95  TRP A CZ2  1 
ATOM   638  C  CZ3  . TRP A 1 95  ? 98.145  66.153  100.163 1.00 91.50  ? 95  TRP A CZ3  1 
ATOM   639  C  CH2  . TRP A 1 95  ? 99.124  66.587  99.268  1.00 91.50  ? 95  TRP A CH2  1 
ATOM   640  N  N    . THR A 1 96  ? 94.417  68.151  98.811  1.00 88.15  ? 96  THR A N    1 
ATOM   641  C  CA   . THR A 1 96  ? 94.959  69.171  99.702  1.00 88.15  ? 96  THR A CA   1 
ATOM   642  C  C    . THR A 1 96  ? 93.855  70.058  100.267 1.00 88.15  ? 96  THR A C    1 
ATOM   643  O  O    . THR A 1 96  ? 93.983  70.543  101.396 1.00 88.15  ? 96  THR A O    1 
ATOM   644  C  CB   . THR A 1 96  ? 96.036  70.001  98.996  1.00 88.15  ? 96  THR A CB   1 
ATOM   645  O  OG1  . THR A 1 96  ? 96.765  70.758  99.969  1.00 88.15  ? 96  THR A OG1  1 
ATOM   646  C  CG2  . THR A 1 96  ? 95.445  70.964  97.997  1.00 88.15  ? 96  THR A CG2  1 
ATOM   647  N  N    . TYR A 1 97  ? 92.752  70.244  99.536  1.00 88.08  ? 97  TYR A N    1 
ATOM   648  C  CA   . TYR A 1 97  ? 91.598  70.935  100.103 1.00 88.08  ? 97  TYR A CA   1 
ATOM   649  C  C    . TYR A 1 97  ? 91.021  70.167  101.284 1.00 88.08  ? 97  TYR A C    1 
ATOM   650  O  O    . TYR A 1 97  ? 90.756  70.744  102.348 1.00 88.08  ? 97  TYR A O    1 
ATOM   651  C  CB   . TYR A 1 97  ? 90.529  71.156  99.036  1.00 88.08  ? 97  TYR A CB   1 
ATOM   652  C  CG   . TYR A 1 97  ? 90.738  72.381  98.184  1.00 88.08  ? 97  TYR A CG   1 
ATOM   653  C  CD1  . TYR A 1 97  ? 91.665  73.340  98.539  1.00 88.08  ? 97  TYR A CD1  1 
ATOM   654  C  CD2  . TYR A 1 97  ? 89.994  72.587  97.037  1.00 88.08  ? 97  TYR A CD2  1 
ATOM   655  C  CE1  . TYR A 1 97  ? 91.857  74.466  97.779  1.00 88.08  ? 97  TYR A CE1  1 
ATOM   656  C  CE2  . TYR A 1 97  ? 90.180  73.708  96.264  1.00 88.08  ? 97  TYR A CE2  1 
ATOM   657  C  CZ   . TYR A 1 97  ? 91.111  74.646  96.641  1.00 88.08  ? 97  TYR A CZ   1 
ATOM   658  O  OH   . TYR A 1 97  ? 91.298  75.768  95.872  1.00 88.08  ? 97  TYR A OH   1 
ATOM   659  N  N    . LEU A 1 98  ? 90.827  68.857  101.122 1.00 82.65  ? 98  LEU A N    1 
ATOM   660  C  CA   . LEU A 1 98  ? 90.307  68.067  102.233 1.00 82.65  ? 98  LEU A CA   1 
ATOM   661  C  C    . LEU A 1 98  ? 91.285  68.039  103.401 1.00 82.65  ? 98  LEU A C    1 
ATOM   662  O  O    . LEU A 1 98  ? 90.870  68.117  104.564 1.00 82.65  ? 98  LEU A O    1 
ATOM   663  C  CB   . LEU A 1 98  ? 89.975  66.650  101.771 1.00 82.65  ? 98  LEU A CB   1 
ATOM   664  C  CG   . LEU A 1 98  ? 88.544  66.462  101.269 1.00 82.65  ? 98  LEU A CG   1 
ATOM   665  C  CD1  . LEU A 1 98  ? 88.328  65.046  100.769 1.00 82.65  ? 98  LEU A CD1  1 
ATOM   666  C  CD2  . LEU A 1 98  ? 87.553  66.798  102.363 1.00 82.65  ? 98  LEU A CD2  1 
ATOM   667  N  N    . LEU A 1 99  ? 92.585  67.939  103.116 1.00 79.99  ? 99  LEU A N    1 
ATOM   668  C  CA   . LEU A 1 99  ? 93.573  67.911  104.189 1.00 79.99  ? 99  LEU A CA   1 
ATOM   669  C  C    . LEU A 1 99  ? 93.610  69.226  104.953 1.00 79.99  ? 99  LEU A C    1 
ATOM   670  O  O    . LEU A 1 99  ? 93.700  69.228  106.185 1.00 79.99  ? 99  LEU A O    1 
ATOM   671  C  CB   . LEU A 1 99  ? 94.953  67.582  103.632 1.00 79.99  ? 99  LEU A CB   1 
ATOM   672  C  CG   . LEU A 1 99  ? 96.029  67.404  104.703 1.00 79.99  ? 99  LEU A CG   1 
ATOM   673  C  CD1  . LEU A 1 99  ? 95.585  66.384  105.734 1.00 79.99  ? 99  LEU A CD1  1 
ATOM   674  C  CD2  . LEU A 1 99  ? 97.349  66.982  104.081 1.00 79.99  ? 99  LEU A CD2  1 
ATOM   675  N  N    . CYS A 1 100 ? 93.525  70.359  104.248 1.00 76.93  ? 100 CYS A N    1 
ATOM   676  C  CA   . CYS A 1 100 ? 93.521  71.642  104.937 1.00 76.93  ? 100 CYS A CA   1 
ATOM   677  C  C    . CYS A 1 100 ? 92.233  71.853  105.725 1.00 76.93  ? 100 CYS A C    1 
ATOM   678  O  O    . CYS A 1 100 ? 92.260  72.454  106.807 1.00 76.93  ? 100 CYS A O    1 
ATOM   679  C  CB   . CYS A 1 100 ? 93.735  72.773  103.938 1.00 76.93  ? 100 CYS A CB   1 
ATOM   680  S  SG   . CYS A 1 100 ? 94.371  74.281  104.682 1.00 76.93  ? 100 CYS A SG   1 
ATOM   681  N  N    . ALA A 1 101 ? 91.104  71.347  105.219 1.00 80.12  ? 101 ALA A N    1 
ATOM   682  C  CA   . ALA A 1 101 ? 89.867  71.394  105.995 1.00 80.12  ? 101 ALA A CA   1 
ATOM   683  C  C    . ALA A 1 101 ? 89.985  70.585  107.280 1.00 80.12  ? 101 ALA A C    1 
ATOM   684  O  O    . ALA A 1 101 ? 89.562  71.036  108.353 1.00 80.12  ? 101 ALA A O    1 
ATOM   685  C  CB   . ALA A 1 101 ? 88.703  70.878  105.158 1.00 80.12  ? 101 ALA A CB   1 
ATOM   686  N  N    . LEU A 1 102 ? 90.554  69.382  107.187 1.00 76.65  ? 102 LEU A N    1 
ATOM   687  C  CA   . LEU A 1 102 ? 90.739  68.564  108.378 1.00 76.65  ? 102 LEU A CA   1 
ATOM   688  C  C    . LEU A 1 102 ? 91.707  69.230  109.341 1.00 76.65  ? 102 LEU A C    1 
ATOM   689  O  O    . LEU A 1 102 ? 91.553  69.122  110.562 1.00 76.65  ? 102 LEU A O    1 
ATOM   690  C  CB   . LEU A 1 102 ? 91.224  67.168  107.988 1.00 76.65  ? 102 LEU A CB   1 
ATOM   691  C  CG   . LEU A 1 102 ? 91.235  66.067  109.052 1.00 76.65  ? 102 LEU A CG   1 
ATOM   692  C  CD1  . LEU A 1 102 ? 90.921  64.738  108.398 1.00 76.65  ? 102 LEU A CD1  1 
ATOM   693  C  CD2  . LEU A 1 102 ? 92.575  65.977  109.766 1.00 76.65  ? 102 LEU A CD2  1 
ATOM   694  N  N    . GLY A 1 103 ? 92.712  69.927  108.808 1.00 74.66  ? 103 GLY A N    1 
ATOM   695  C  CA   . GLY A 1 103 ? 93.610  70.680  109.662 1.00 74.66  ? 103 GLY A CA   1 
ATOM   696  C  C    . GLY A 1 103 ? 92.900  71.786  110.413 1.00 74.66  ? 103 GLY A C    1 
ATOM   697  O  O    . GLY A 1 103 ? 93.138  71.995  111.603 1.00 74.66  ? 103 GLY A O    1 
ATOM   698  N  N    . LEU A 1 104 ? 92.004  72.501  109.733 1.00 74.24  ? 104 LEU A N    1 
ATOM   699  C  CA   . LEU A 1 104 ? 91.243  73.549  110.407 1.00 74.24  ? 104 LEU A CA   1 
ATOM   700  C  C    . LEU A 1 104 ? 90.353  72.971  111.503 1.00 74.24  ? 104 LEU A C    1 
ATOM   701  O  O    . LEU A 1 104 ? 90.277  73.519  112.613 1.00 74.24  ? 104 LEU A O    1 
ATOM   702  C  CB   . LEU A 1 104 ? 90.398  74.313  109.393 1.00 74.24  ? 104 LEU A CB   1 
ATOM   703  C  CG   . LEU A 1 104 ? 90.132  75.768  109.751 1.00 74.24  ? 104 LEU A CG   1 
ATOM   704  C  CD1  . LEU A 1 104 ? 91.454  76.481  109.940 1.00 74.24  ? 104 LEU A CD1  1 
ATOM   705  C  CD2  . LEU A 1 104 ? 89.311  76.430  108.672 1.00 74.24  ? 104 LEU A CD2  1 
ATOM   706  N  N    . PHE A 1 105 ? 89.680  71.856  111.209 1.00 78.85  ? 105 PHE A N    1 
ATOM   707  C  CA   . PHE A 1 105 ? 88.795  71.248  112.201 1.00 78.85  ? 105 PHE A CA   1 
ATOM   708  C  C    . PHE A 1 105 ? 89.572  70.728  113.403 1.00 78.85  ? 105 PHE A C    1 
ATOM   709  O  O    . PHE A 1 105 ? 89.154  70.930  114.551 1.00 78.85  ? 105 PHE A O    1 
ATOM   710  C  CB   . PHE A 1 105 ? 87.982  70.125  111.564 1.00 78.85  ? 105 PHE A CB   1 
ATOM   711  C  CG   . PHE A 1 105 ? 86.613  69.966  112.151 1.00 78.85  ? 105 PHE A CG   1 
ATOM   712  C  CD1  . PHE A 1 105 ? 85.621  70.891  111.882 1.00 78.85  ? 105 PHE A CD1  1 
ATOM   713  C  CD2  . PHE A 1 105 ? 86.316  68.887  112.965 1.00 78.85  ? 105 PHE A CD2  1 
ATOM   714  C  CE1  . PHE A 1 105 ? 84.357  70.747  112.417 1.00 78.85  ? 105 PHE A CE1  1 
ATOM   715  C  CE2  . PHE A 1 105 ? 85.052  68.738  113.501 1.00 78.85  ? 105 PHE A CE2  1 
ATOM   716  C  CZ   . PHE A 1 105 ? 84.073  69.669  113.227 1.00 78.85  ? 105 PHE A CZ   1 
ATOM   717  N  N    . ILE A 1 106 ? 90.709  70.065  113.169 1.00 80.78  ? 106 ILE A N    1 
ATOM   718  C  CA   . ILE A 1 106 ? 91.490  69.572  114.296 1.00 80.78  ? 106 ILE A CA   1 
ATOM   719  C  C    . ILE A 1 106 ? 92.097  70.737  115.067 1.00 80.78  ? 106 ILE A C    1 
ATOM   720  O  O    . ILE A 1 106 ? 92.272  70.649  116.285 1.00 80.78  ? 106 ILE A O    1 
ATOM   721  C  CB   . ILE A 1 106 ? 92.558  68.556  113.838 1.00 80.78  ? 106 ILE A CB   1 
ATOM   722  C  CG1  . ILE A 1 106 ? 93.187  67.860  115.044 1.00 80.78  ? 106 ILE A CG1  1 
ATOM   723  C  CG2  . ILE A 1 106 ? 93.661  69.213  113.051 1.00 80.78  ? 106 ILE A CG2  1 
ATOM   724  C  CD1  . ILE A 1 106 ? 94.001  66.638  114.688 1.00 80.78  ? 106 ILE A CD1  1 
ATOM   725  N  N    . TYR A 1 107 ? 92.381  71.858  114.396 1.00 76.59  ? 107 TYR A N    1 
ATOM   726  C  CA   . TYR A 1 107 ? 92.878  73.030  115.104 1.00 76.59  ? 107 TYR A CA   1 
ATOM   727  C  C    . TYR A 1 107 ? 91.827  73.578  116.056 1.00 76.59  ? 107 TYR A C    1 
ATOM   728  O  O    . TYR A 1 107 ? 92.126  73.903  117.212 1.00 76.59  ? 107 TYR A O    1 
ATOM   729  C  CB   . TYR A 1 107 ? 93.300  74.109  114.111 1.00 76.59  ? 107 TYR A CB   1 
ATOM   730  C  CG   . TYR A 1 107 ? 93.300  75.475  114.733 1.00 76.59  ? 107 TYR A CG   1 
ATOM   731  C  CD1  . TYR A 1 107 ? 94.306  75.849  115.601 1.00 76.59  ? 107 TYR A CD1  1 
ATOM   732  C  CD2  . TYR A 1 107 ? 92.288  76.380  114.472 1.00 76.59  ? 107 TYR A CD2  1 
ATOM   733  C  CE1  . TYR A 1 107 ? 94.314  77.085  116.182 1.00 76.59  ? 107 TYR A CE1  1 
ATOM   734  C  CE2  . TYR A 1 107 ? 92.280  77.616  115.055 1.00 76.59  ? 107 TYR A CE2  1 
ATOM   735  C  CZ   . TYR A 1 107 ? 93.298  77.963  115.910 1.00 76.59  ? 107 TYR A CZ   1 
ATOM   736  O  OH   . TYR A 1 107 ? 93.308  79.207  116.489 1.00 76.59  ? 107 TYR A OH   1 
ATOM   737  N  N    . GLN A 1 108 ? 90.588  73.711  115.578 1.00 83.63  ? 108 GLN A N    1 
ATOM   738  C  CA   . GLN A 1 108 ? 89.517  74.194  116.445 1.00 83.63  ? 108 GLN A CA   1 
ATOM   739  C  C    . GLN A 1 108 ? 89.288  73.241  117.608 1.00 83.63  ? 108 GLN A C    1 
ATOM   740  O  O    . GLN A 1 108 ? 89.103  73.673  118.757 1.00 83.63  ? 108 GLN A O    1 
ATOM   741  C  CB   . GLN A 1 108 ? 88.230  74.380  115.646 1.00 83.63  ? 108 GLN A CB   1 
ATOM   742  C  CG   . GLN A 1 108 ? 87.002  74.576  116.509 1.00 83.63  ? 108 GLN A CG   1 
ATOM   743  C  CD   . GLN A 1 108 ? 85.727  74.589  115.705 1.00 83.63  ? 108 GLN A CD   1 
ATOM   744  O  OE1  . GLN A 1 108 ? 85.577  73.833  114.749 1.00 83.63  ? 108 GLN A OE1  1 
ATOM   745  N  NE2  . GLN A 1 108 ? 84.795  75.453  116.088 1.00 83.63  ? 108 GLN A NE2  1 
ATOM   746  N  N    . SER A 1 109 ? 89.316  71.936  117.328 1.00 90.79  ? 109 SER A N    1 
ATOM   747  C  CA   . SER A 1 109 ? 89.134  70.947  118.385 1.00 90.79  ? 109 SER A CA   1 
ATOM   748  C  C    . SER A 1 109 ? 90.233  71.049  119.434 1.00 90.79  ? 109 SER A C    1 
ATOM   749  O  O    . SER A 1 109 ? 89.954  71.022  120.639 1.00 90.79  ? 109 SER A O    1 
ATOM   750  C  CB   . SER A 1 109 ? 89.097  69.544  117.786 1.00 90.79  ? 109 SER A CB   1 
ATOM   751  O  OG   . SER A 1 109 ? 89.343  68.566  118.778 1.00 90.79  ? 109 SER A OG   1 
ATOM   752  N  N    . LEU A 1 110 ? 91.485  71.201  119.000 1.00 89.18  ? 110 LEU A N    1 
ATOM   753  C  CA   . LEU A 1 110 ? 92.575  71.286  119.961 1.00 89.18  ? 110 LEU A CA   1 
ATOM   754  C  C    . LEU A 1 110 ? 92.546  72.597  120.734 1.00 89.18  ? 110 LEU A C    1 
ATOM   755  O  O    . LEU A 1 110 ? 92.956  72.624  121.896 1.00 89.18  ? 110 LEU A O    1 
ATOM   756  C  CB   . LEU A 1 110 ? 93.921  71.097  119.263 1.00 89.18  ? 110 LEU A CB   1 
ATOM   757  C  CG   . LEU A 1 110 ? 94.161  69.688  118.718 1.00 89.18  ? 110 LEU A CG   1 
ATOM   758  C  CD1  . LEU A 1 110 ? 95.498  69.592  118.008 1.00 89.18  ? 110 LEU A CD1  1 
ATOM   759  C  CD2  . LEU A 1 110 ? 94.055  68.648  119.812 1.00 89.18  ? 110 LEU A CD2  1 
ATOM   760  N  N    . ASP A 1 111 ? 92.055  73.682  120.132 1.00 87.51  ? 111 ASP A N    1 
ATOM   761  C  CA   . ASP A 1 111 ? 91.921  74.927  120.889 1.00 87.51  ? 111 ASP A CA   1 
ATOM   762  C  C    . ASP A 1 111 ? 90.857  74.806  121.976 1.00 87.51  ? 111 ASP A C    1 
ATOM   763  O  O    . ASP A 1 111 ? 91.067  75.243  123.115 1.00 87.51  ? 111 ASP A O    1 
ATOM   764  C  CB   . ASP A 1 111 ? 91.598  76.086  119.954 1.00 87.51  ? 111 ASP A CB   1 
ATOM   765  C  CG   . ASP A 1 111 ? 91.894  77.434  120.576 1.00 87.51  ? 111 ASP A CG   1 
ATOM   766  O  OD1  . ASP A 1 111 ? 92.345  77.471  121.738 1.00 87.51  ? 111 ASP A OD1  1 
ATOM   767  O  OD2  . ASP A 1 111 ? 91.670  78.459  119.904 1.00 87.51  ? 111 ASP A OD2  1 
ATOM   768  N  N    . ALA A 1 112 ? 89.705  74.222  121.652 1.00 95.94  ? 112 ALA A N    1 
ATOM   769  C  CA   . ALA A 1 112 ? 88.704  74.023  122.698 1.00 95.94  ? 112 ALA A CA   1 
ATOM   770  C  C    . ALA A 1 112 ? 89.238  73.102  123.788 1.00 95.94  ? 112 ALA A C    1 
ATOM   771  O  O    . ALA A 1 112 ? 89.042  73.353  124.986 1.00 95.94  ? 112 ALA A O    1 
ATOM   772  C  CB   . ALA A 1 112 ? 87.418  73.466  122.097 1.00 95.94  ? 112 ALA A CB   1 
ATOM   773  N  N    . ILE A 1 113 ? 89.963  72.060  123.382 1.00 98.64  ? 113 ILE A N    1 
ATOM   774  C  CA   . ILE A 1 113 ? 90.544  71.123  124.334 1.00 98.64  ? 113 ILE A CA   1 
ATOM   775  C  C    . ILE A 1 113 ? 91.554  71.820  125.236 1.00 98.64  ? 113 ILE A C    1 
ATOM   776  O  O    . ILE A 1 113 ? 91.591  71.573  126.446 1.00 98.64  ? 113 ILE A O    1 
ATOM   777  C  CB   . ILE A 1 113 ? 91.161  69.934  123.579 1.00 98.64  ? 113 ILE A CB   1 
ATOM   778  C  CG1  . ILE A 1 113 ? 90.072  68.921  123.230 1.00 98.64  ? 113 ILE A CG1  1 
ATOM   779  C  CG2  . ILE A 1 113 ? 92.264  69.281  124.380 1.00 98.64  ? 113 ILE A CG2  1 
ATOM   780  C  CD1  . ILE A 1 113 ? 90.503  67.877  122.236 1.00 98.64  ? 113 ILE A CD1  1 
ATOM   781  N  N    . ASP A 1 114 ? 92.382  72.710  124.676 1.00 98.44  ? 114 ASP A N    1 
ATOM   782  C  CA   . ASP A 1 114 ? 93.445  73.297  125.488 1.00 98.44  ? 114 ASP A CA   1 
ATOM   783  C  C    . ASP A 1 114 ? 92.858  74.274  126.489 1.00 98.44  ? 114 ASP A C    1 
ATOM   784  O  O    . ASP A 1 114 ? 93.310  74.331  127.639 1.00 98.44  ? 114 ASP A O    1 
ATOM   785  C  CB   . ASP A 1 114 ? 94.517  73.952  124.585 1.00 98.44  ? 114 ASP A CB   1 
ATOM   786  C  CG   . ASP A 1 114 ? 94.123  75.330  123.973 1.00 98.44  ? 114 ASP A CG   1 
ATOM   787  O  OD1  . ASP A 1 114 ? 93.158  76.010  124.357 1.00 98.44  ? 114 ASP A OD1  1 
ATOM   788  O  OD2  . ASP A 1 114 ? 94.766  75.711  122.982 1.00 98.44  ? 114 ASP A OD2  1 
ATOM   789  N  N    . GLY A 1 115 ? 91.832  75.022  126.069 1.00 104.89 ? 115 GLY A N    1 
ATOM   790  C  CA   . GLY A 1 115 ? 91.132  75.886  127.002 1.00 104.89 ? 115 GLY A CA   1 
ATOM   791  C  C    . GLY A 1 115 ? 90.488  75.110  128.135 1.00 104.89 ? 115 GLY A C    1 
ATOM   792  O  O    . GLY A 1 115 ? 90.592  75.491  129.304 1.00 104.89 ? 115 GLY A O    1 
ATOM   793  N  N    . LYS A 1 116 ? 89.890  73.972  127.815 1.00 112.01 ? 116 LYS A N    1 
ATOM   794  C  CA   . LYS A 1 116 ? 89.226  73.173  128.835 1.00 112.01 ? 116 LYS A CA   1 
ATOM   795  C  C    . LYS A 1 116 ? 90.009  72.214  129.725 1.00 112.01 ? 116 LYS A C    1 
ATOM   796  O  O    . LYS A 1 116 ? 89.773  72.152  130.930 1.00 112.01 ? 116 LYS A O    1 
ATOM   797  C  CB   . LYS A 1 116 ? 88.229  72.231  128.189 1.00 112.01 ? 116 LYS A CB   1 
ATOM   798  C  CG   . LYS A 1 116 ? 86.940  72.904  127.762 1.00 112.01 ? 116 LYS A CG   1 
ATOM   799  C  CD   . LYS A 1 116 ? 85.828  71.885  127.573 1.00 112.01 ? 116 LYS A CD   1 
ATOM   800  C  CE   . LYS A 1 116 ? 84.836  72.341  126.517 1.00 112.01 ? 116 LYS A CE   1 
ATOM   801  N  NZ   . LYS A 1 116 ? 84.101  71.206  125.891 1.00 112.01 ? 116 LYS A NZ   1 
ATOM   802  N  N    . GLN A 1 117 ? 90.879  71.430  129.116 1.00 115.47 ? 117 GLN A N    1 
ATOM   803  C  CA   . GLN A 1 117 ? 91.667  70.495  129.872 1.00 115.47 ? 117 GLN A CA   1 
ATOM   804  C  C    . GLN A 1 117 ? 92.838  70.989  130.595 1.00 115.47 ? 117 GLN A C    1 
ATOM   805  O  O    . GLN A 1 117 ? 93.474  70.242  131.302 1.00 115.47 ? 117 GLN A O    1 
ATOM   806  C  CB   . GLN A 1 117 ? 92.645  69.762  128.988 1.00 115.47 ? 117 GLN A CB   1 
ATOM   807  C  CG   . GLN A 1 117 ? 93.414  68.657  129.682 1.00 115.47 ? 117 GLN A CG   1 
ATOM   808  C  CD   . GLN A 1 117 ? 94.255  67.839  128.729 1.00 115.47 ? 117 GLN A CD   1 
ATOM   809  O  OE1  . GLN A 1 117 ? 94.204  68.032  127.516 1.00 115.47 ? 117 GLN A OE1  1 
ATOM   810  N  NE2  . GLN A 1 117 ? 95.032  66.914  129.273 1.00 115.47 ? 117 GLN A NE2  1 
ATOM   811  N  N    . ALA A 1 118 ? 93.154  72.240  130.355 1.00 117.15 ? 118 ALA A N    1 
ATOM   812  C  CA   . ALA A 1 118 ? 94.253  72.820  131.037 1.00 117.15 ? 118 ALA A CA   1 
ATOM   813  C  C    . ALA A 1 118 ? 93.785  73.231  132.390 1.00 117.15 ? 118 ALA A C    1 
ATOM   814  O  O    . ALA A 1 118 ? 94.562  73.272  133.335 1.00 117.15 ? 118 ALA A O    1 
ATOM   815  C  CB   . ALA A 1 118 ? 94.550  74.152  130.424 1.00 117.15 ? 118 ALA A CB   1 
ATOM   816  N  N    . ARG A 1 119 ? 92.509  73.544  132.499 1.00 120.84 ? 119 ARG A N    1 
ATOM   817  C  CA   . ARG A 1 119 ? 92.001  74.014  133.763 1.00 120.84 ? 119 ARG A CA   1 
ATOM   818  C  C    . ARG A 1 119 ? 92.023  72.876  134.727 1.00 120.84 ? 119 ARG A C    1 
ATOM   819  O  O    . ARG A 1 119 ? 91.935  73.062  135.934 1.00 120.84 ? 119 ARG A O    1 
ATOM   820  C  CB   . ARG A 1 119 ? 90.587  74.526  133.598 1.00 120.84 ? 119 ARG A CB   1 
ATOM   821  C  CG   . ARG A 1 119 ? 90.475  75.680  132.621 1.00 120.84 ? 119 ARG A CG   1 
ATOM   822  C  CD   . ARG A 1 119 ? 90.039  76.950  133.332 1.00 120.84 ? 119 ARG A CD   1 
ATOM   823  N  NE   . ARG A 1 119 ? 89.930  78.077  132.414 1.00 120.84 ? 119 ARG A NE   1 
ATOM   824  C  CZ   . ARG A 1 119 ? 88.885  78.291  131.622 1.00 120.84 ? 119 ARG A CZ   1 
ATOM   825  N  NH1  . ARG A 1 119 ? 87.858  77.456  131.635 1.00 120.84 ? 119 ARG A NH1  1 
ATOM   826  N  NH2  . ARG A 1 119 ? 88.865  79.340  130.816 1.00 120.84 ? 119 ARG A NH2  1 
ATOM   827  N  N    . ARG A 1 120 ? 92.157  71.682  134.198 1.00 126.06 ? 120 ARG A N    1 
ATOM   828  C  CA   . ARG A 1 120 ? 92.101  70.528  135.052 1.00 126.06 ? 120 ARG A CA   1 
ATOM   829  C  C    . ARG A 1 120 ? 93.239  70.390  136.060 1.00 126.06 ? 120 ARG A C    1 
ATOM   830  O  O    . ARG A 1 120 ? 93.108  69.636  137.015 1.00 126.06 ? 120 ARG A O    1 
ATOM   831  C  CB   . ARG A 1 120 ? 92.178  69.273  134.178 1.00 126.06 ? 120 ARG A CB   1 
ATOM   832  C  CG   . ARG A 1 120 ? 92.083  67.968  134.943 1.00 126.06 ? 120 ARG A CG   1 
ATOM   833  C  CD   . ARG A 1 120 ? 92.215  66.770  134.017 1.00 126.06 ? 120 ARG A CD   1 
ATOM   834  N  NE   . ARG A 1 120 ? 93.533  66.690  133.398 1.00 126.06 ? 120 ARG A NE   1 
ATOM   835  C  CZ   . ARG A 1 120 ? 93.807  65.971  132.317 1.00 126.06 ? 120 ARG A CZ   1 
ATOM   836  N  NH1  . ARG A 1 120 ? 92.848  65.276  131.726 1.00 126.06 ? 120 ARG A NH1  1 
ATOM   837  N  NH2  . ARG A 1 120 ? 95.034  65.959  131.822 1.00 126.06 ? 120 ARG A NH2  1 
ATOM   838  N  N    . THR A 1 121 ? 94.328  71.130  135.905 1.00 129.22 ? 121 THR A N    1 
ATOM   839  C  CA   . THR A 1 121 ? 95.500  70.948  136.754 1.00 129.22 ? 121 THR A CA   1 
ATOM   840  C  C    . THR A 1 121 ? 95.463  72.409  137.132 1.00 129.22 ? 121 THR A C    1 
ATOM   841  O  O    . THR A 1 121 ? 94.757  73.186  136.495 1.00 129.22 ? 121 THR A O    1 
ATOM   842  C  CB   . THR A 1 121 ? 96.892  70.610  136.213 1.00 129.22 ? 121 THR A CB   1 
ATOM   843  O  OG1  . THR A 1 121 ? 97.230  71.499  135.143 1.00 129.22 ? 121 THR A OG1  1 
ATOM   844  C  CG2  . THR A 1 121 ? 96.922  69.181  135.697 1.00 129.22 ? 121 THR A CG2  1 
ATOM   845  N  N    . ASN A 1 122 ? 96.204  72.807  138.159 1.00 128.51 ? 122 ASN A N    1 
ATOM   846  C  CA   . ASN A 1 122 ? 96.275  74.227  138.491 1.00 128.51 ? 122 ASN A CA   1 
ATOM   847  C  C    . ASN A 1 122 ? 97.287  74.673  137.476 1.00 128.51 ? 122 ASN A C    1 
ATOM   848  O  O    . ASN A 1 122 ? 98.360  75.144  137.835 1.00 128.51 ? 122 ASN A O    1 
ATOM   849  C  CB   . ASN A 1 122 ? 97.074  74.470  139.756 1.00 128.51 ? 122 ASN A CB   1 
ATOM   850  C  CG   . ASN A 1 122 ? 96.587  75.686  140.517 1.00 128.51 ? 122 ASN A CG   1 
ATOM   851  O  OD1  . ASN A 1 122 ? 95.733  75.583  141.398 1.00 128.51 ? 122 ASN A OD1  1 
ATOM   852  N  ND2  . ASN A 1 122 ? 97.118  76.853  140.168 1.00 128.51 ? 122 ASN A ND2  1 
ATOM   853  N  N    . SER A 1 123 ? 96.957  74.496  136.212 1.00 126.79 ? 123 SER A N    1 
ATOM   854  C  CA   . SER A 1 123 ? 97.855  74.879  135.166 1.00 126.79 ? 123 SER A CA   1 
ATOM   855  C  C    . SER A 1 123 ? 97.358  76.193  134.708 1.00 126.79 ? 123 SER A C    1 
ATOM   856  O  O    . SER A 1 123 ? 98.083  76.948  134.078 1.00 126.79 ? 123 SER A O    1 
ATOM   857  C  CB   . SER A 1 123 ? 97.764  73.890  134.039 1.00 126.79 ? 123 SER A CB   1 
ATOM   858  O  OG   . SER A 1 123 ? 96.438  73.836  133.554 1.00 126.79 ? 123 SER A OG   1 
ATOM   859  N  N    . CYS A 1 124 ? 96.104  76.467  135.026 1.00 118.97 ? 124 CYS A N    1 
ATOM   860  C  CA   . CYS A 1 124 ? 95.558  77.759  134.712 1.00 118.97 ? 124 CYS A CA   1 
ATOM   861  C  C    . CYS A 1 124 ? 96.700  78.623  135.135 1.00 118.97 ? 124 CYS A C    1 
ATOM   862  O  O    . CYS A 1 124 ? 97.122  78.590  136.286 1.00 118.97 ? 124 CYS A O    1 
ATOM   863  C  CB   . CYS A 1 124 ? 94.279  77.959  135.492 1.00 118.97 ? 124 CYS A CB   1 
ATOM   864  S  SG   . CYS A 1 124 ? 92.984  76.798  134.995 1.00 118.97 ? 124 CYS A SG   1 
ATOM   865  N  N    . SER A 1 125 ? 97.230  79.390  134.210 1.00 107.21 ? 125 SER A N    1 
ATOM   866  C  CA   . SER A 1 125 ? 98.392  80.161  134.516 1.00 107.21 ? 125 SER A CA   1 
ATOM   867  C  C    . SER A 1 125 ? 98.286  81.174  133.430 1.00 107.21 ? 125 SER A C    1 
ATOM   868  O  O    . SER A 1 125 ? 97.525  80.999  132.486 1.00 107.21 ? 125 SER A O    1 
ATOM   869  C  CB   . SER A 1 125 ? 99.654  79.432  134.093 1.00 107.21 ? 125 SER A CB   1 
ATOM   870  O  OG   . SER A 1 125 ? 99.538  78.957  132.765 1.00 107.21 ? 125 SER A OG   1 
ATOM   871  N  N    . PRO A 1 126 ? 98.988  82.285  133.580 1.00 102.66 ? 126 PRO A N    1 
ATOM   872  C  CA   . PRO A 1 126 ? 98.982  83.155  132.436 1.00 102.66 ? 126 PRO A CA   1 
ATOM   873  C  C    . PRO A 1 126 ? 99.823  82.920  131.248 1.00 102.66 ? 126 PRO A C    1 
ATOM   874  O  O    . PRO A 1 126 ? 99.953  83.821  130.455 1.00 102.66 ? 126 PRO A O    1 
ATOM   875  C  CB   . PRO A 1 126 ? 99.519  84.342  133.172 1.00 102.66 ? 126 PRO A CB   1 
ATOM   876  C  CG   . PRO A 1 126 ? 100.247 83.815  134.372 1.00 102.66 ? 126 PRO A CG   1 
ATOM   877  C  CD   . PRO A 1 126 ? 100.424 82.361  134.148 1.00 102.66 ? 126 PRO A CD   1 
ATOM   878  N  N    . LEU A 1 127 ? 100.423 81.759  131.113 1.00 98.33  ? 127 LEU A N    1 
ATOM   879  C  CA   . LEU A 1 127 ? 101.135 81.484  129.895 1.00 98.33  ? 127 LEU A CA   1 
ATOM   880  C  C    . LEU A 1 127 ? 100.224 80.629  129.095 1.00 98.33  ? 127 LEU A C    1 
ATOM   881  O  O    . LEU A 1 127 ? 100.577 80.154  128.035 1.00 98.33  ? 127 LEU A O    1 
ATOM   882  C  CB   . LEU A 1 127 ? 102.419 80.760  130.162 1.00 98.33  ? 127 LEU A CB   1 
ATOM   883  C  CG   . LEU A 1 127 ? 103.268 80.328  128.970 1.00 98.33  ? 127 LEU A CG   1 
ATOM   884  C  CD1  . LEU A 1 127 ? 103.739 81.547  128.196 1.00 98.33  ? 127 LEU A CD1  1 
ATOM   885  C  CD2  . LEU A 1 127 ? 104.451 79.473  129.388 1.00 98.33  ? 127 LEU A CD2  1 
ATOM   886  N  N    . GLY A 1 128 ? 99.058  80.386  129.655 1.00 96.66  ? 128 GLY A N    1 
ATOM   887  C  CA   . GLY A 1 128 ? 98.072  79.574  128.985 1.00 96.66  ? 128 GLY A CA   1 
ATOM   888  C  C    . GLY A 1 128 ? 97.355  80.487  128.070 1.00 96.66  ? 128 GLY A C    1 
ATOM   889  O  O    . GLY A 1 128 ? 96.695  80.075  127.132 1.00 96.66  ? 128 GLY A O    1 
ATOM   890  N  N    . GLU A 1 129 ? 97.411  81.750  128.378 1.00 94.42  ? 129 GLU A N    1 
ATOM   891  C  CA   . GLU A 1 129 ? 96.887  82.674  127.447 1.00 94.42  ? 129 GLU A CA   1 
ATOM   892  C  C    . GLU A 1 129 ? 98.196  83.273  127.064 1.00 94.42  ? 129 GLU A C    1 
ATOM   893  O  O    . GLU A 1 129 ? 99.216  82.633  127.217 1.00 94.42  ? 129 GLU A O    1 
ATOM   894  C  CB   . GLU A 1 129 ? 95.929  83.598  128.106 1.00 94.42  ? 129 GLU A CB   1 
ATOM   895  C  CG   . GLU A 1 129 ? 94.665  82.916  128.586 1.00 94.42  ? 129 GLU A CG   1 
ATOM   896  C  CD   . GLU A 1 129 ? 93.731  83.853  129.319 1.00 94.42  ? 129 GLU A CD   1 
ATOM   897  O  OE1  . GLU A 1 129 ? 94.149  84.992  129.621 1.00 94.42  ? 129 GLU A OE1  1 
ATOM   898  O  OE2  . GLU A 1 129 ? 92.579  83.457  129.588 1.00 94.42  ? 129 GLU A OE2  1 
ATOM   899  N  N    . LEU A 1 130 ? 98.234  84.474  126.565 1.00 86.17  ? 130 LEU A N    1 
ATOM   900  C  CA   . LEU A 1 130 ? 99.469  84.970  126.033 1.00 86.17  ? 130 LEU A CA   1 
ATOM   901  C  C    . LEU A 1 130 ? 100.060 83.845  125.249 1.00 86.17  ? 130 LEU A C    1 
ATOM   902  O  O    . LEU A 1 130 ? 101.262 83.763  125.139 1.00 86.17  ? 130 LEU A O    1 
ATOM   903  C  CB   . LEU A 1 130 ? 100.411 85.396  127.092 1.00 86.17  ? 130 LEU A CB   1 
ATOM   904  C  CG   . LEU A 1 130 ? 101.698 85.826  126.396 1.00 86.17  ? 130 LEU A CG   1 
ATOM   905  C  CD1  . LEU A 1 130 ? 101.474 87.025  125.487 1.00 86.17  ? 130 LEU A CD1  1 
ATOM   906  C  CD2  . LEU A 1 130 ? 102.728 86.185  127.446 1.00 86.17  ? 130 LEU A CD2  1 
ATOM   907  N  N    . PHE A 1 131 ? 99.203  82.955  124.773 1.00 87.56  ? 131 PHE A N    1 
ATOM   908  C  CA   . PHE A 1 131 ? 99.622  81.861  123.909 1.00 87.56  ? 131 PHE A CA   1 
ATOM   909  C  C    . PHE A 1 131 ? 98.413  81.606  123.042 1.00 87.56  ? 131 PHE A C    1 
ATOM   910  O  O    . PHE A 1 131 ? 98.427  81.949  121.882 1.00 87.56  ? 131 PHE A O    1 
ATOM   911  C  CB   . PHE A 1 131 ? 99.994  80.608  124.664 1.00 87.56  ? 131 PHE A CB   1 
ATOM   912  C  CG   . PHE A 1 131 ? 100.357 79.457  123.795 1.00 87.56  ? 131 PHE A CG   1 
ATOM   913  C  CD1  . PHE A 1 131 ? 101.604 79.368  123.234 1.00 87.56  ? 131 PHE A CD1  1 
ATOM   914  C  CD2  . PHE A 1 131 ? 99.437  78.469  123.537 1.00 87.56  ? 131 PHE A CD2  1 
ATOM   915  C  CE1  . PHE A 1 131 ? 101.934 78.304  122.429 1.00 87.56  ? 131 PHE A CE1  1 
ATOM   916  C  CE2  . PHE A 1 131 ? 99.755  77.403  122.734 1.00 87.56  ? 131 PHE A CE2  1 
ATOM   917  C  CZ   . PHE A 1 131 ? 101.006 77.321  122.177 1.00 87.56  ? 131 PHE A CZ   1 
ATOM   918  N  N    . ASP A 1 132 ? 97.350  81.043  123.590 1.00 82.53  ? 132 ASP A N    1 
ATOM   919  C  CA   . ASP A 1 132 ? 96.171  80.887  122.770 1.00 82.53  ? 132 ASP A CA   1 
ATOM   920  C  C    . ASP A 1 132 ? 95.919  82.190  122.043 1.00 82.53  ? 132 ASP A C    1 
ATOM   921  O  O    . ASP A 1 132 ? 95.498  82.161  120.924 1.00 82.53  ? 132 ASP A O    1 
ATOM   922  C  CB   . ASP A 1 132 ? 94.948  80.432  123.521 1.00 82.53  ? 132 ASP A CB   1 
ATOM   923  C  CG   . ASP A 1 132 ? 93.893  79.878  122.604 1.00 82.53  ? 132 ASP A CG   1 
ATOM   924  O  OD1  . ASP A 1 132 ? 94.241  79.448  121.494 1.00 82.53  ? 132 ASP A OD1  1 
ATOM   925  O  OD2  . ASP A 1 132 ? 92.713  79.869  122.983 1.00 82.53  ? 132 ASP A OD2  1 
ATOM   926  N  N    . HIS A 1 133 ? 96.158  83.340  122.629 1.00 76.42  ? 133 HIS A N    1 
ATOM   927  C  CA   . HIS A 1 133 ? 96.052  84.531  121.864 1.00 76.42  ? 133 HIS A CA   1 
ATOM   928  C  C    . HIS A 1 133 ? 97.205  84.877  120.985 1.00 76.42  ? 133 HIS A C    1 
ATOM   929  O  O    . HIS A 1 133 ? 97.180  85.892  120.353 1.00 76.42  ? 133 HIS A O    1 
ATOM   930  C  CB   . HIS A 1 133 ? 95.671  85.490  122.942 1.00 76.42  ? 133 HIS A CB   1 
ATOM   931  C  CG   . HIS A 1 133 ? 94.328  85.226  123.527 1.00 76.42  ? 133 HIS A CG   1 
ATOM   932  N  ND1  . HIS A 1 133 ? 94.157  84.794  124.820 1.00 76.42  ? 133 HIS A ND1  1 
ATOM   933  C  CD2  . HIS A 1 133 ? 93.091  85.320  122.994 1.00 76.42  ? 133 HIS A CD2  1 
ATOM   934  C  CE1  . HIS A 1 133 ? 92.870  84.643  125.065 1.00 76.42  ? 133 HIS A CE1  1 
ATOM   935  N  NE2  . HIS A 1 133 ? 92.202  84.958  123.974 1.00 76.42  ? 133 HIS A NE2  1 
ATOM   936  N  N    . GLY A 1 134 ? 98.291  84.134  121.029 1.00 69.91  ? 134 GLY A N    1 
ATOM   937  C  CA   . GLY A 1 134 ? 99.269  84.259  119.957 1.00 69.91  ? 134 GLY A CA   1 
ATOM   938  C  C    . GLY A 1 134 ? 99.065  83.230  118.858 1.00 69.91  ? 134 GLY A C    1 
ATOM   939  O  O    . GLY A 1 134 ? 99.077  83.555  117.658 1.00 69.91  ? 134 GLY A O    1 
ATOM   940  N  N    . CYS A 1 135 ? 98.854  81.971  119.254 1.00 76.12  ? 135 CYS A N    1 
ATOM   941  C  CA   . CYS A 1 135 ? 98.584  80.928  118.272 1.00 76.12  ? 135 CYS A CA   1 
ATOM   942  C  C    . CYS A 1 135 ? 97.293  81.209  117.513 1.00 76.12  ? 135 CYS A C    1 
ATOM   943  O  O    . CYS A 1 135 ? 97.192  80.924  116.315 1.00 76.12  ? 135 CYS A O    1 
ATOM   944  C  CB   . CYS A 1 135 ? 98.522  79.567  118.960 1.00 76.12  ? 135 CYS A CB   1 
ATOM   945  S  SG   . CYS A 1 135 ? 100.091 79.031  119.665 1.00 76.12  ? 135 CYS A SG   1 
ATOM   946  N  N    . ASP A 1 136 ? 96.300  81.784  118.190 1.00 71.39  ? 136 ASP A N    1 
ATOM   947  C  CA   . ASP A 1 136 ? 95.052  82.125  117.524 1.00 71.39  ? 136 ASP A CA   1 
ATOM   948  C  C    . ASP A 1 136 ? 95.248  83.235  116.505 1.00 71.39  ? 136 ASP A C    1 
ATOM   949  O  O    . ASP A 1 136 ? 94.605  83.221  115.455 1.00 71.39  ? 136 ASP A O    1 
ATOM   950  C  CB   . ASP A 1 136 ? 94.002  82.518  118.556 1.00 71.39  ? 136 ASP A CB   1 
ATOM   951  C  CG   . ASP A 1 136 ? 93.480  81.326  119.330 1.00 71.39  ? 136 ASP A CG   1 
ATOM   952  O  OD1  . ASP A 1 136 ? 93.603  80.197  118.821 1.00 71.39  ? 136 ASP A OD1  1 
ATOM   953  O  OD2  . ASP A 1 136 ? 92.965  81.508  120.448 1.00 71.39  ? 136 ASP A OD2  1 
ATOM   954  N  N    . SER A 1 137 ? 96.135  84.192  116.781 1.00 64.28  ? 137 SER A N    1 
ATOM   955  C  CA   . SER A 1 137 ? 96.428  85.230  115.793 1.00 64.28  ? 137 SER A CA   1 
ATOM   956  C  C    . SER A 1 137 ? 97.073  84.645  114.540 1.00 64.28  ? 137 SER A C    1 
ATOM   957  O  O    . SER A 1 137 ? 96.660  84.943  113.400 1.00 64.28  ? 137 SER A O    1 
ATOM   958  C  CB   . SER A 1 137 ? 97.335  86.287  116.407 1.00 64.28  ? 137 SER A CB   1 
ATOM   959  O  OG   . SER A 1 137 ? 97.944  87.053  115.391 1.00 64.28  ? 137 SER A OG   1 
ATOM   960  N  N    . LEU A 1 138 ? 98.093  83.803  114.733 1.00 65.42  ? 138 LEU A N    1 
ATOM   961  C  CA   . LEU A 1 138 ? 98.723  83.153  113.582 1.00 65.42  ? 138 LEU A CA   1 
ATOM   962  C  C    . LEU A 1 138 ? 97.715  82.329  112.794 1.00 65.42  ? 138 LEU A C    1 
ATOM   963  O  O    . LEU A 1 138 ? 97.692  82.368  111.554 1.00 65.42  ? 138 LEU A O    1 
ATOM   964  C  CB   . LEU A 1 138 ? 99.880  82.267  114.027 1.00 65.42  ? 138 LEU A CB   1 
ATOM   965  C  CG   . LEU A 1 138 ? 101.247 82.926  114.037 1.00 65.42  ? 138 LEU A CG   1 
ATOM   966  C  CD1  . LEU A 1 138 ? 102.287 81.970  114.579 1.00 65.42  ? 138 LEU A CD1  1 
ATOM   967  C  CD2  . LEU A 1 138 ? 101.584 83.336  112.629 1.00 65.42  ? 138 LEU A CD2  1 
ATOM   968  N  N    . SER A 1 139 ? 96.861  81.590  113.499 1.00 67.08  ? 139 SER A N    1 
ATOM   969  C  CA   . SER A 1 139 ? 95.870  80.774  112.824 1.00 67.08  ? 139 SER A CA   1 
ATOM   970  C  C    . SER A 1 139 ? 94.844  81.625  112.098 1.00 67.08  ? 139 SER A C    1 
ATOM   971  O  O    . SER A 1 139 ? 94.347  81.213  111.050 1.00 67.08  ? 139 SER A O    1 
ATOM   972  C  CB   . SER A 1 139 ? 95.182  79.857  113.822 1.00 67.08  ? 139 SER A CB   1 
ATOM   973  O  OG   . SER A 1 139 ? 94.286  78.991  113.158 1.00 67.08  ? 139 SER A OG   1 
ATOM   974  N  N    . THR A 1 140 ? 94.519  82.806  112.624 1.00 67.08  ? 140 THR A N    1 
ATOM   975  C  CA   . THR A 1 140 ? 93.611  83.706  111.922 1.00 67.08  ? 140 THR A CA   1 
ATOM   976  C  C    . THR A 1 140 ? 94.174  84.096  110.569 1.00 67.08  ? 140 THR A C    1 
ATOM   977  O  O    . THR A 1 140 ? 93.482  84.013  109.546 1.00 67.08  ? 140 THR A O    1 
ATOM   978  C  CB   . THR A 1 140 ? 93.357  84.957  112.754 1.00 67.08  ? 140 THR A CB   1 
ATOM   979  O  OG1  . THR A 1 140 ? 92.762  84.593  114.004 1.00 67.08  ? 140 THR A OG1  1 
ATOM   980  C  CG2  . THR A 1 140 ? 92.457  85.911  112.007 1.00 67.08  ? 140 THR A CG2  1 
ATOM   981  N  N    . VAL A 1 141 ? 95.443  84.501  110.543 1.00 62.31  ? 141 VAL A N    1 
ATOM   982  C  CA   . VAL A 1 141 ? 96.044  84.908  109.270 1.00 62.31  ? 141 VAL A CA   1 
ATOM   983  C  C    . VAL A 1 141 ? 96.087  83.738  108.293 1.00 62.31  ? 141 VAL A C    1 
ATOM   984  O  O    . VAL A 1 141 ? 95.675  83.858  107.127 1.00 62.31  ? 141 VAL A O    1 
ATOM   985  C  CB   . VAL A 1 141 ? 97.444  85.491  109.502 1.00 62.31  ? 141 VAL A CB   1 
ATOM   986  C  CG1  . VAL A 1 141 ? 98.185  85.547  108.200 1.00 62.31  ? 141 VAL A CG1  1 
ATOM   987  C  CG2  . VAL A 1 141 ? 97.325  86.862  110.098 1.00 62.31  ? 141 VAL A CG2  1 
ATOM   988  N  N    . PHE A 1 142 ? 96.567  82.583  108.760 1.00 63.94  ? 142 PHE A N    1 
ATOM   989  C  CA   . PHE A 1 142 ? 96.709  81.434  107.868 1.00 63.94  ? 142 PHE A CA   1 
ATOM   990  C  C    . PHE A 1 142 ? 95.357  80.942  107.374 1.00 63.94  ? 142 PHE A C    1 
ATOM   991  O  O    . PHE A 1 142 ? 95.222  80.542  106.213 1.00 63.94  ? 142 PHE A O    1 
ATOM   992  C  CB   . PHE A 1 142 ? 97.455  80.313  108.572 1.00 63.94  ? 142 PHE A CB   1 
ATOM   993  C  CG   . PHE A 1 142 ? 98.937  80.418  108.463 1.00 63.94  ? 142 PHE A CG   1 
ATOM   994  C  CD1  . PHE A 1 142 ? 99.605  81.504  108.989 1.00 63.94  ? 142 PHE A CD1  1 
ATOM   995  C  CD2  . PHE A 1 142 ? 99.666  79.424  107.855 1.00 63.94  ? 142 PHE A CD2  1 
ATOM   996  C  CE1  . PHE A 1 142 ? 100.968 81.601  108.898 1.00 63.94  ? 142 PHE A CE1  1 
ATOM   997  C  CE2  . PHE A 1 142 ? 101.029 79.518  107.762 1.00 63.94  ? 142 PHE A CE2  1 
ATOM   998  C  CZ   . PHE A 1 142 ? 101.679 80.606  108.286 1.00 63.94  ? 142 PHE A CZ   1 
ATOM   999  N  N    . MET A 1 143 ? 94.341  80.977  108.230 1.00 67.02  ? 143 MET A N    1 
ATOM   1000 C  CA   . MET A 1 143 ? 93.020  80.519  107.839 1.00 67.02  ? 143 MET A CA   1 
ATOM   1001 C  C    . MET A 1 143 ? 92.389  81.467  106.836 1.00 67.02  ? 143 MET A C    1 
ATOM   1002 O  O    . MET A 1 143 ? 91.696  81.025  105.915 1.00 67.02  ? 143 MET A O    1 
ATOM   1003 C  CB   . MET A 1 143 ? 92.141  80.386  109.073 1.00 67.02  ? 143 MET A CB   1 
ATOM   1004 C  CG   . MET A 1 143 ? 90.768  79.868  108.798 1.00 67.02  ? 143 MET A CG   1 
ATOM   1005 S  SD   . MET A 1 143 ? 89.845  79.741  110.328 1.00 67.02  ? 143 MET A SD   1 
ATOM   1006 C  CE   . MET A 1 143 ? 89.580  81.473  110.652 1.00 67.02  ? 143 MET A CE   1 
ATOM   1007 N  N    . ALA A 1 144 ? 92.608  82.775  106.999 1.00 65.42  ? 144 ALA A N    1 
ATOM   1008 C  CA   . ALA A 1 144 ? 92.101  83.721  106.011 1.00 65.42  ? 144 ALA A CA   1 
ATOM   1009 C  C    . ALA A 1 144 ? 92.735  83.481  104.651 1.00 65.42  ? 144 ALA A C    1 
ATOM   1010 O  O    . ALA A 1 144 ? 92.037  83.458  103.628 1.00 65.42  ? 144 ALA A O    1 
ATOM   1011 C  CB   . ALA A 1 144 ? 92.353  85.154  106.472 1.00 65.42  ? 144 ALA A CB   1 
ATOM   1012 N  N    . VAL A 1 145 ? 94.052  83.263  104.624 1.00 60.93  ? 145 VAL A N    1 
ATOM   1013 C  CA   . VAL A 1 145 ? 94.710  82.984  103.350 1.00 60.93  ? 145 VAL A CA   1 
ATOM   1014 C  C    . VAL A 1 145 ? 94.184  81.690  102.743 1.00 60.93  ? 145 VAL A C    1 
ATOM   1015 O  O    . VAL A 1 145 ? 93.889  81.633  101.547 1.00 60.93  ? 145 VAL A O    1 
ATOM   1016 C  CB   . VAL A 1 145 ? 96.235  82.950  103.526 1.00 60.93  ? 145 VAL A CB   1 
ATOM   1017 C  CG1  . VAL A 1 145 ? 96.898  82.495  102.255 1.00 60.93  ? 145 VAL A CG1  1 
ATOM   1018 C  CG2  . VAL A 1 145 ? 96.729  84.317  103.884 1.00 60.93  ? 145 VAL A CG2  1 
ATOM   1019 N  N    . GLY A 1 146 ? 94.031  80.644  103.557 1.00 66.47  ? 146 GLY A N    1 
ATOM   1020 C  CA   . GLY A 1 146 ? 93.564  79.371  103.027 1.00 66.47  ? 146 GLY A CA   1 
ATOM   1021 C  C    . GLY A 1 146 ? 92.150  79.435  102.478 1.00 66.47  ? 146 GLY A C    1 
ATOM   1022 O  O    . GLY A 1 146 ? 91.877  78.935  101.382 1.00 66.47  ? 146 GLY A O    1 
ATOM   1023 N  N    . ALA A 1 147 ? 91.241  80.073  103.216 1.00 70.33  ? 147 ALA A N    1 
ATOM   1024 C  CA   . ALA A 1 147 ? 89.870  80.211  102.741 1.00 70.33  ? 147 ALA A CA   1 
ATOM   1025 C  C    . ALA A 1 147 ? 89.806  81.060  101.487 1.00 70.33  ? 147 ALA A C    1 
ATOM   1026 O  O    . ALA A 1 147 ? 89.027  80.767  100.574 1.00 70.33  ? 147 ALA A O    1 
ATOM   1027 C  CB   . ALA A 1 147 ? 88.995  80.810  103.832 1.00 70.33  ? 147 ALA A CB   1 
ATOM   1028 N  N    . SER A 1 148 ? 90.617  82.113  101.417 1.00 69.16  ? 148 SER A N    1 
ATOM   1029 C  CA   . SER A 1 148 ? 90.584  82.967  100.244 1.00 69.16  ? 148 SER A CA   1 
ATOM   1030 C  C    . SER A 1 148 ? 91.182  82.279  99.021  1.00 69.16  ? 148 SER A C    1 
ATOM   1031 O  O    . SER A 1 148 ? 90.752  82.546  97.897  1.00 69.16  ? 148 SER A O    1 
ATOM   1032 C  CB   . SER A 1 148 ? 91.303  84.269  100.555 1.00 69.16  ? 148 SER A CB   1 
ATOM   1033 O  OG   . SER A 1 148 ? 92.604  84.006  101.038 1.00 69.16  ? 148 SER A OG   1 
ATOM   1034 N  N    . ILE A 1 149 ? 92.168  81.402  99.213  1.00 66.16  ? 149 ILE A N    1 
ATOM   1035 C  CA   . ILE A 1 149 ? 92.673  80.640  98.077  1.00 66.16  ? 149 ILE A CA   1 
ATOM   1036 C  C    . ILE A 1 149 ? 91.636  79.641  97.598  1.00 66.16  ? 149 ILE A C    1 
ATOM   1037 O  O    . ILE A 1 149 ? 91.382  79.525  96.396  1.00 66.16  ? 149 ILE A O    1 
ATOM   1038 C  CB   . ILE A 1 149 ? 93.988  79.931  98.423  1.00 66.16  ? 149 ILE A CB   1 
ATOM   1039 C  CG1  . ILE A 1 149 ? 95.077  80.938  98.746  1.00 66.16  ? 149 ILE A CG1  1 
ATOM   1040 C  CG2  . ILE A 1 149 ? 94.432  79.082  97.264  1.00 66.16  ? 149 ILE A CG2  1 
ATOM   1041 C  CD1  . ILE A 1 149 ? 96.285  80.291  99.334  1.00 66.16  ? 149 ILE A CD1  1 
ATOM   1042 N  N    . ALA A 1 150 ? 91.025  78.903  98.526  1.00 76.41  ? 150 ALA A N    1 
ATOM   1043 C  CA   . ALA A 1 150 ? 90.134  77.819  98.125  1.00 76.41  ? 150 ALA A CA   1 
ATOM   1044 C  C    . ALA A 1 150 ? 88.923  78.328  97.362  1.00 76.41  ? 150 ALA A C    1 
ATOM   1045 O  O    . ALA A 1 150 ? 88.367  77.605  96.531  1.00 76.41  ? 150 ALA A O    1 
ATOM   1046 C  CB   . ALA A 1 150 ? 89.689  77.023  99.345  1.00 76.41  ? 150 ALA A CB   1 
ATOM   1047 N  N    . ALA A 1 151 ? 88.504  79.560  97.615  1.00 81.24  ? 151 ALA A N    1 
ATOM   1048 C  CA   . ALA A 1 151 ? 87.422  80.154  96.849  1.00 81.24  ? 151 ALA A CA   1 
ATOM   1049 C  C    . ALA A 1 151 ? 87.901  80.807  95.563  1.00 81.24  ? 151 ALA A C    1 
ATOM   1050 O  O    . ALA A 1 151 ? 87.070  81.348  94.824  1.00 81.24  ? 151 ALA A O    1 
ATOM   1051 C  CB   . ALA A 1 151 ? 86.670  81.178  97.699  1.00 81.24  ? 151 ALA A CB   1 
ATOM   1052 N  N    . ARG A 1 152 ? 89.209  80.776  95.290  1.00 87.25  ? 152 ARG A N    1 
ATOM   1053 C  CA   . ARG A 1 152 ? 89.812  81.322  94.072  1.00 87.25  ? 152 ARG A CA   1 
ATOM   1054 C  C    . ARG A 1 152 ? 89.481  82.803  93.899  1.00 87.25  ? 152 ARG A C    1 
ATOM   1055 O  O    . ARG A 1 152 ? 88.930  83.226  92.885  1.00 87.25  ? 152 ARG A O    1 
ATOM   1056 C  CB   . ARG A 1 152 ? 89.388  80.526  92.835  1.00 87.25  ? 152 ARG A CB   1 
ATOM   1057 C  CG   . ARG A 1 152 ? 90.172  79.260  92.611  1.00 87.25  ? 152 ARG A CG   1 
ATOM   1058 C  CD   . ARG A 1 152 ? 89.413  78.322  91.701  1.00 87.25  ? 152 ARG A CD   1 
ATOM   1059 N  NE   . ARG A 1 152 ? 88.909  79.001  90.513  1.00 87.25  ? 152 ARG A NE   1 
ATOM   1060 C  CZ   . ARG A 1 152 ? 89.587  79.116  89.380  1.00 87.25  ? 152 ARG A CZ   1 
ATOM   1061 N  NH1  . ARG A 1 152 ? 90.801  78.594  89.279  1.00 87.25  ? 152 ARG A NH1  1 
ATOM   1062 N  NH2  . ARG A 1 152 ? 89.055  79.751  88.345  1.00 87.25  ? 152 ARG A NH2  1 
ATOM   1063 N  N    . LEU A 1 153 ? 89.842  83.593  94.899  1.00 77.71  ? 153 LEU A N    1 
ATOM   1064 C  CA   . LEU A 1 153 ? 89.527  85.011  94.842  1.00 77.71  ? 153 LEU A CA   1 
ATOM   1065 C  C    . LEU A 1 153 ? 90.480  85.812  93.966  1.00 77.71  ? 153 LEU A C    1 
ATOM   1066 O  O    . LEU A 1 153 ? 90.328  87.034  93.880  1.00 77.71  ? 153 LEU A O    1 
ATOM   1067 C  CB   . LEU A 1 153 ? 89.503  85.608  96.242  1.00 77.71  ? 153 LEU A CB   1 
ATOM   1068 C  CG   . LEU A 1 153 ? 88.200  85.403  97.003  1.00 77.71  ? 153 LEU A CG   1 
ATOM   1069 C  CD1  . LEU A 1 153 ? 88.279  86.092  98.343  1.00 77.71  ? 153 LEU A CD1  1 
ATOM   1070 C  CD2  . LEU A 1 153 ? 87.037  85.937  96.205  1.00 77.71  ? 153 LEU A CD2  1 
ATOM   1071 N  N    . GLY A 1 154 ? 91.437  85.166  93.297  1.00 82.67  ? 154 GLY A N    1 
ATOM   1072 C  CA   . GLY A 1 154 ? 92.346  85.888  92.426  1.00 82.67  ? 154 GLY A CA   1 
ATOM   1073 C  C    . GLY A 1 154 ? 91.675  86.561  91.248  1.00 82.67  ? 154 GLY A C    1 
ATOM   1074 O  O    . GLY A 1 154 ? 92.204  87.543  90.724  1.00 82.67  ? 154 GLY A O    1 
ATOM   1075 N  N    . THR A 1 155 ? 90.517  86.058  90.820  1.00 83.17  ? 155 THR A N    1 
ATOM   1076 C  CA   . THR A 1 155 ? 89.769  86.728  89.765  1.00 83.17  ? 155 THR A CA   1 
ATOM   1077 C  C    . THR A 1 155 ? 89.156  88.036  90.240  1.00 83.17  ? 155 THR A C    1 
ATOM   1078 O  O    . THR A 1 155 ? 88.781  88.866  89.409  1.00 83.17  ? 155 THR A O    1 
ATOM   1079 C  CB   . THR A 1 155 ? 88.674  85.815  89.225  1.00 83.17  ? 155 THR A CB   1 
ATOM   1080 O  OG1  . THR A 1 155 ? 87.538  85.876  90.094  1.00 83.17  ? 155 THR A OG1  1 
ATOM   1081 C  CG2  . THR A 1 155 ? 89.174  84.386  89.143  1.00 83.17  ? 155 THR A CG2  1 
ATOM   1082 N  N    . TYR A 1 156 ? 89.040  88.232  91.549  1.00 83.06  ? 156 TYR A N    1 
ATOM   1083 C  CA   . TYR A 1 156 ? 88.595  89.493  92.136  1.00 83.06  ? 156 TYR A CA   1 
ATOM   1084 C  C    . TYR A 1 156 ? 89.619  89.904  93.181  1.00 83.06  ? 156 TYR A C    1 
ATOM   1085 O  O    . TYR A 1 156 ? 89.358  89.811  94.385  1.00 83.06  ? 156 TYR A O    1 
ATOM   1086 C  CB   . TYR A 1 156 ? 87.210  89.356  92.771  1.00 83.06  ? 156 TYR A CB   1 
ATOM   1087 C  CG   . TYR A 1 156 ? 86.043  89.543  91.834  1.00 83.06  ? 156 TYR A CG   1 
ATOM   1088 C  CD1  . TYR A 1 156 ? 86.073  90.495  90.830  1.00 83.06  ? 156 TYR A CD1  1 
ATOM   1089 C  CD2  . TYR A 1 156 ? 84.898  88.774  91.970  1.00 83.06  ? 156 TYR A CD2  1 
ATOM   1090 C  CE1  . TYR A 1 156 ? 84.999  90.671  89.977  1.00 83.06  ? 156 TYR A CE1  1 
ATOM   1091 C  CE2  . TYR A 1 156 ? 83.820  88.942  91.124  1.00 83.06  ? 156 TYR A CE2  1 
ATOM   1092 C  CZ   . TYR A 1 156 ? 83.874  89.891  90.132  1.00 83.06  ? 156 TYR A CZ   1 
ATOM   1093 O  OH   . TYR A 1 156 ? 82.802  90.062  89.287  1.00 83.06  ? 156 TYR A OH   1 
ATOM   1094 N  N    . PRO A 1 157 ? 90.799  90.361  92.752  1.00 73.01  ? 157 PRO A N    1 
ATOM   1095 C  CA   . PRO A 1 157 ? 91.913  90.536  93.699  1.00 73.01  ? 157 PRO A CA   1 
ATOM   1096 C  C    . PRO A 1 157 ? 91.621  91.492  94.832  1.00 73.01  ? 157 PRO A C    1 
ATOM   1097 O  O    . PRO A 1 157 ? 92.069  91.243  95.958  1.00 73.01  ? 157 PRO A O    1 
ATOM   1098 C  CB   . PRO A 1 157 ? 93.053  91.053  92.812  1.00 73.01  ? 157 PRO A CB   1 
ATOM   1099 C  CG   . PRO A 1 157 ? 92.659  90.684  91.434  1.00 73.01  ? 157 PRO A CG   1 
ATOM   1100 C  CD   . PRO A 1 157 ? 91.174  90.765  91.392  1.00 73.01  ? 157 PRO A CD   1 
ATOM   1101 N  N    . ASP A 1 158 ? 90.843  92.548  94.573  1.00 71.60  ? 158 ASP A N    1 
ATOM   1102 C  CA   . ASP A 1 158 ? 90.496  93.509  95.617  1.00 71.60  ? 158 ASP A CA   1 
ATOM   1103 C  C    . ASP A 1 158 ? 89.869  92.813  96.820  1.00 71.60  ? 158 ASP A C    1 
ATOM   1104 O  O    . ASP A 1 158 ? 90.339  92.976  97.955  1.00 71.60  ? 158 ASP A O    1 
ATOM   1105 C  CB   . ASP A 1 158 ? 89.551  94.565  95.051  1.00 71.60  ? 158 ASP A CB   1 
ATOM   1106 C  CG   . ASP A 1 158 ? 89.520  95.828  95.882  1.00 71.60  ? 158 ASP A CG   1 
ATOM   1107 O  OD1  . ASP A 1 158 ? 90.593  96.427  96.091  1.00 71.60  ? 158 ASP A OD1  1 
ATOM   1108 O  OD2  . ASP A 1 158 ? 88.421  96.224  96.324  1.00 71.60  ? 158 ASP A OD2  1 
ATOM   1109 N  N    . TRP A 1 159 ? 88.849  91.979  96.578  1.00 70.90  ? 159 TRP A N    1 
ATOM   1110 C  CA   . TRP A 1 159 ? 88.253  91.195  97.655  1.00 70.90  ? 159 TRP A CA   1 
ATOM   1111 C  C    . TRP A 1 159 ? 89.299  90.341  98.353  1.00 70.90  ? 159 TRP A C    1 
ATOM   1112 O  O    . TRP A 1 159 ? 89.406  90.364  99.585  1.00 70.90  ? 159 TRP A O    1 
ATOM   1113 C  CB   . TRP A 1 159 ? 87.131  90.308  97.118  1.00 70.90  ? 159 TRP A CB   1 
ATOM   1114 C  CG   . TRP A 1 159 ? 85.918  91.032  96.635  1.00 70.90  ? 159 TRP A CG   1 
ATOM   1115 C  CD1  . TRP A 1 159 ? 85.394  90.988  95.382  1.00 70.90  ? 159 TRP A CD1  1 
ATOM   1116 C  CD2  . TRP A 1 159 ? 85.068  91.896  97.396  1.00 70.90  ? 159 TRP A CD2  1 
ATOM   1117 N  NE1  . TRP A 1 159 ? 84.270  91.771  95.310  1.00 70.90  ? 159 TRP A NE1  1 
ATOM   1118 C  CE2  . TRP A 1 159 ? 84.049  92.342  96.536  1.00 70.90  ? 159 TRP A CE2  1 
ATOM   1119 C  CE3  . TRP A 1 159 ? 85.066  92.338  98.721  1.00 70.90  ? 159 TRP A CE3  1 
ATOM   1120 C  CZ2  . TRP A 1 159 ? 83.046  93.207  96.952  1.00 70.90  ? 159 TRP A CZ2  1 
ATOM   1121 C  CZ3  . TRP A 1 159 ? 84.070  93.197  99.134  1.00 70.90  ? 159 TRP A CZ3  1 
ATOM   1122 C  CH2  . TRP A 1 159 ? 83.075  93.624  98.253  1.00 70.90  ? 159 TRP A CH2  1 
ATOM   1123 N  N    . PHE A 1 160 ? 90.134  89.643  97.573  1.00 63.46  ? 160 PHE A N    1 
ATOM   1124 C  CA   . PHE A 1 160 ? 91.162  88.782  98.147  1.00 63.46  ? 160 PHE A CA   1 
ATOM   1125 C  C    . PHE A 1 160 ? 92.094  89.563  99.050  1.00 63.46  ? 160 PHE A C    1 
ATOM   1126 O  O    . PHE A 1 160 ? 92.674  88.999  99.985  1.00 63.46  ? 160 PHE A O    1 
ATOM   1127 C  CB   . PHE A 1 160 ? 91.964  88.103  97.041  1.00 63.46  ? 160 PHE A CB   1 
ATOM   1128 C  CG   . PHE A 1 160 ? 93.118  87.294  97.540  1.00 63.46  ? 160 PHE A CG   1 
ATOM   1129 C  CD1  . PHE A 1 160 ? 92.920  86.042  98.058  1.00 63.46  ? 160 PHE A CD1  1 
ATOM   1130 C  CD2  . PHE A 1 160 ? 94.402  87.787  97.478  1.00 63.46  ? 160 PHE A CD2  1 
ATOM   1131 C  CE1  . PHE A 1 160 ? 93.978  85.298  98.509  1.00 63.46  ? 160 PHE A CE1  1 
ATOM   1132 C  CE2  . PHE A 1 160 ? 95.458  87.044  97.930  1.00 63.46  ? 160 PHE A CE2  1 
ATOM   1133 C  CZ   . PHE A 1 160 ? 95.243  85.799  98.447  1.00 63.46  ? 160 PHE A CZ   1 
ATOM   1134 N  N    . PHE A 1 161 ? 92.251  90.855  98.789  1.00 58.62  ? 161 PHE A N    1 
ATOM   1135 C  CA   . PHE A 1 161 ? 92.916  91.708  99.756  1.00 58.62  ? 161 PHE A CA   1 
ATOM   1136 C  C    . PHE A 1 161 ? 91.956  92.080  100.873 1.00 58.62  ? 161 PHE A C    1 
ATOM   1137 O  O    . PHE A 1 161 ? 92.138  91.668  102.025 1.00 58.62  ? 161 PHE A O    1 
ATOM   1138 C  CB   . PHE A 1 161 ? 93.446  92.955  99.055  1.00 58.62  ? 161 PHE A CB   1 
ATOM   1139 C  CG   . PHE A 1 161 ? 93.921  94.015  99.984  1.00 58.62  ? 161 PHE A CG   1 
ATOM   1140 C  CD1  . PHE A 1 161 ? 95.176  93.946  100.547 1.00 58.62  ? 161 PHE A CD1  1 
ATOM   1141 C  CD2  . PHE A 1 161 ? 93.121  95.096  100.274 1.00 58.62  ? 161 PHE A CD2  1 
ATOM   1142 C  CE1  . PHE A 1 161 ? 95.617  94.930  101.391 1.00 58.62  ? 161 PHE A CE1  1 
ATOM   1143 C  CE2  . PHE A 1 161 ? 93.553  96.071  101.118 1.00 58.62  ? 161 PHE A CE2  1 
ATOM   1144 C  CZ   . PHE A 1 161 ? 94.805  95.995  101.678 1.00 58.62  ? 161 PHE A CZ   1 
ATOM   1145 N  N    . PHE A 1 162 ? 90.878  92.780  100.516 1.00 61.48  ? 162 PHE A N    1 
ATOM   1146 C  CA   . PHE A 1 162 ? 90.081  93.505  101.500 1.00 61.48  ? 162 PHE A CA   1 
ATOM   1147 C  C    . PHE A 1 162 ? 89.476  92.560  102.522 1.00 61.48  ? 162 PHE A C    1 
ATOM   1148 O  O    . PHE A 1 162 ? 89.690  92.718  103.731 1.00 61.48  ? 162 PHE A O    1 
ATOM   1149 C  CB   . PHE A 1 162 ? 88.998  94.304  100.781 1.00 61.48  ? 162 PHE A CB   1 
ATOM   1150 C  CG   . PHE A 1 162 ? 87.822  94.662  101.634 1.00 61.48  ? 162 PHE A CG   1 
ATOM   1151 C  CD1  . PHE A 1 162 ? 87.889  95.720  102.518 1.00 61.48  ? 162 PHE A CD1  1 
ATOM   1152 C  CD2  . PHE A 1 162 ? 86.632  93.962  101.526 1.00 61.48  ? 162 PHE A CD2  1 
ATOM   1153 C  CE1  . PHE A 1 162 ? 86.799  96.062  103.292 1.00 61.48  ? 162 PHE A CE1  1 
ATOM   1154 C  CE2  . PHE A 1 162 ? 85.541  94.298  102.298 1.00 61.48  ? 162 PHE A CE2  1 
ATOM   1155 C  CZ   . PHE A 1 162 ? 85.625  95.349  103.182 1.00 61.48  ? 162 PHE A CZ   1 
ATOM   1156 N  N    . CYS A 1 163 ? 88.784  91.523  102.040 1.00 60.70  ? 163 CYS A N    1 
ATOM   1157 C  CA   . CYS A 1 163 ? 88.218  90.505  102.916 1.00 60.70  ? 163 CYS A CA   1 
ATOM   1158 C  C    . CYS A 1 163 ? 89.263  89.943  103.863 1.00 60.70  ? 163 CYS A C    1 
ATOM   1159 O  O    . CYS A 1 163 ? 89.044  89.902  105.079 1.00 60.70  ? 163 CYS A O    1 
ATOM   1160 C  CB   . CYS A 1 163 ? 87.607  89.386  102.084 1.00 60.70  ? 163 CYS A CB   1 
ATOM   1161 S  SG   . CYS A 1 163 ? 87.214  87.916  103.025 1.00 60.70  ? 163 CYS A SG   1 
ATOM   1162 N  N    . SER A 1 164 ? 90.440  89.601  103.333 1.00 54.33  ? 164 SER A N    1 
ATOM   1163 C  CA   . SER A 1 164 ? 91.478  89.021  104.173 1.00 54.33  ? 164 SER A CA   1 
ATOM   1164 C  C    . SER A 1 164 ? 91.887  89.976  105.279 1.00 54.33  ? 164 SER A C    1 
ATOM   1165 O  O    . SER A 1 164 ? 92.015  89.572  106.437 1.00 54.33  ? 164 SER A O    1 
ATOM   1166 C  CB   . SER A 1 164 ? 92.692  88.637  103.337 1.00 54.33  ? 164 SER A CB   1 
ATOM   1167 O  OG   . SER A 1 164 ? 93.662  88.005  104.148 1.00 54.33  ? 164 SER A OG   1 
ATOM   1168 N  N    . PHE A 1 165 ? 92.031  91.261  104.959 1.00 51.20  ? 165 PHE A N    1 
ATOM   1169 C  CA   . PHE A 1 165 ? 92.437  92.183  106.010 1.00 51.20  ? 165 PHE A CA   1 
ATOM   1170 C  C    . PHE A 1 165 ? 91.292  92.465  106.967 1.00 51.20  ? 165 PHE A C    1 
ATOM   1171 O  O    . PHE A 1 165 ? 91.537  92.730  108.149 1.00 51.20  ? 165 PHE A O    1 
ATOM   1172 C  CB   . PHE A 1 165 ? 92.999  93.462  105.416 1.00 51.20  ? 165 PHE A CB   1 
ATOM   1173 C  CG   . PHE A 1 165 ? 94.471  93.400  105.194 1.00 51.20  ? 165 PHE A CG   1 
ATOM   1174 C  CD1  . PHE A 1 165 ? 94.985  92.789  104.073 1.00 51.20  ? 165 PHE A CD1  1 
ATOM   1175 C  CD2  . PHE A 1 165 ? 95.342  93.907  106.127 1.00 51.20  ? 165 PHE A CD2  1 
ATOM   1176 C  CE1  . PHE A 1 165 ? 96.339  92.711  103.877 1.00 51.20  ? 165 PHE A CE1  1 
ATOM   1177 C  CE2  . PHE A 1 165 ? 96.695  93.830  105.934 1.00 51.20  ? 165 PHE A CE2  1 
ATOM   1178 C  CZ   . PHE A 1 165 ? 97.190  93.233  104.806 1.00 51.20  ? 165 PHE A CZ   1 
ATOM   1179 N  N    . ILE A 1 166 ? 90.047  92.357  106.503 1.00 54.63  ? 166 ILE A N    1 
ATOM   1180 C  CA   . ILE A 1 166 ? 88.937  92.390  107.446 1.00 54.63  ? 166 ILE A CA   1 
ATOM   1181 C  C    . ILE A 1 166 ? 89.049  91.214  108.398 1.00 54.63  ? 166 ILE A C    1 
ATOM   1182 O  O    . ILE A 1 166 ? 88.837  91.356  109.610 1.00 54.63  ? 166 ILE A O    1 
ATOM   1183 C  CB   . ILE A 1 166 ? 87.592  92.410  106.704 1.00 54.63  ? 166 ILE A CB   1 
ATOM   1184 C  CG1  . ILE A 1 166 ? 87.458  93.715  105.933 1.00 54.63  ? 166 ILE A CG1  1 
ATOM   1185 C  CG2  . ILE A 1 166 ? 86.450  92.266  107.669 1.00 54.63  ? 166 ILE A CG2  1 
ATOM   1186 C  CD1  . ILE A 1 166 ? 87.511  94.932  106.818 1.00 54.63  ? 166 ILE A CD1  1 
ATOM   1187 N  N    . GLY A 1 167 ? 89.482  90.063  107.884 1.00 58.62  ? 167 GLY A N    1 
ATOM   1188 C  CA   . GLY A 1 167 ? 89.727  88.912  108.729 1.00 58.62  ? 167 GLY A CA   1 
ATOM   1189 C  C    . GLY A 1 167 ? 90.770  89.155  109.795 1.00 58.62  ? 167 GLY A C    1 
ATOM   1190 O  O    . GLY A 1 167 ? 90.792  88.441  110.799 1.00 58.62  ? 167 GLY A O    1 
ATOM   1191 N  N    . MET A 1 168 ? 91.634  90.150  109.606 1.00 52.40  ? 168 MET A N    1 
ATOM   1192 C  CA   . MET A 1 168 ? 92.494  90.557  110.705 1.00 52.40  ? 168 MET A CA   1 
ATOM   1193 C  C    . MET A 1 168 ? 91.763  91.524  111.621 1.00 52.40  ? 168 MET A C    1 
ATOM   1194 O  O    . MET A 1 168 ? 91.733  91.331  112.841 1.00 52.40  ? 168 MET A O    1 
ATOM   1195 C  CB   . MET A 1 168 ? 93.769  91.203  110.174 1.00 52.40  ? 168 MET A CB   1 
ATOM   1196 C  CG   . MET A 1 168 ? 94.694  90.262  109.435 1.00 52.40  ? 168 MET A CG   1 
ATOM   1197 S  SD   . MET A 1 168 ? 96.165  91.113  108.837 1.00 52.40  ? 168 MET A SD   1 
ATOM   1198 C  CE   . MET A 1 168 ? 96.979  89.795  107.950 1.00 52.40  ? 168 MET A CE   1 
ATOM   1199 N  N    . PHE A 1 169 ? 91.127  92.540  111.030 1.00 50.46  ? 169 PHE A N    1 
ATOM   1200 C  CA   . PHE A 1 169 ? 90.670  93.694  111.797 1.00 50.46  ? 169 PHE A CA   1 
ATOM   1201 C  C    . PHE A 1 169 ? 89.641  93.302  112.843 1.00 50.46  ? 169 PHE A C    1 
ATOM   1202 O  O    . PHE A 1 169 ? 89.728  93.737  113.997 1.00 50.46  ? 169 PHE A O    1 
ATOM   1203 C  CB   . PHE A 1 169 ? 90.093  94.738  110.853 1.00 50.46  ? 169 PHE A CB   1 
ATOM   1204 C  CG   . PHE A 1 169 ? 89.562  95.946  111.540 1.00 50.46  ? 169 PHE A CG   1 
ATOM   1205 C  CD1  . PHE A 1 169 ? 90.415  96.836  112.159 1.00 50.46  ? 169 PHE A CD1  1 
ATOM   1206 C  CD2  . PHE A 1 169 ? 88.205  96.197  111.564 1.00 50.46  ? 169 PHE A CD2  1 
ATOM   1207 C  CE1  . PHE A 1 169 ? 89.924  97.955  112.786 1.00 50.46  ? 169 PHE A CE1  1 
ATOM   1208 C  CE2  . PHE A 1 169 ? 87.711  97.314  112.188 1.00 50.46  ? 169 PHE A CE2  1 
ATOM   1209 C  CZ   . PHE A 1 169 ? 88.571  98.194  112.801 1.00 50.46  ? 169 PHE A CZ   1 
ATOM   1210 N  N    . VAL A 1 170 ? 88.691  92.442  112.467 1.00 55.85  ? 170 VAL A N    1 
ATOM   1211 C  CA   . VAL A 1 170 ? 87.693  91.954  113.413 1.00 55.85  ? 170 VAL A CA   1 
ATOM   1212 C  C    . VAL A 1 170 ? 88.369  91.323  114.613 1.00 55.85  ? 170 VAL A C    1 
ATOM   1213 O  O    . VAL A 1 170 ? 88.042  91.642  115.762 1.00 55.85  ? 170 VAL A O    1 
ATOM   1214 C  CB   . VAL A 1 170 ? 86.754  90.953  112.728 1.00 55.85  ? 170 VAL A CB   1 
ATOM   1215 C  CG1  . VAL A 1 170 ? 85.664  90.546  113.675 1.00 55.85  ? 170 VAL A CG1  1 
ATOM   1216 C  CG2  . VAL A 1 170 ? 86.180  91.564  111.504 1.00 55.85  ? 170 VAL A CG2  1 
ATOM   1217 N  N    . PHE A 1 171 ? 89.356  90.458  114.355 1.00 57.58  ? 171 PHE A N    1 
ATOM   1218 C  CA   . PHE A 1 171 ? 90.130  89.847  115.429 1.00 57.58  ? 171 PHE A CA   1 
ATOM   1219 C  C    . PHE A 1 171 ? 90.677  90.910  116.362 1.00 57.58  ? 171 PHE A C    1 
ATOM   1220 O  O    . PHE A 1 171 ? 90.464  90.853  117.579 1.00 57.58  ? 171 PHE A O    1 
ATOM   1221 C  CB   . PHE A 1 171 ? 91.260  89.009  114.835 1.00 57.58  ? 171 PHE A CB   1 
ATOM   1222 C  CG   . PHE A 1 171 ? 92.133  88.345  115.853 1.00 57.58  ? 171 PHE A CG   1 
ATOM   1223 C  CD1  . PHE A 1 171 ? 91.824  87.092  116.325 1.00 57.58  ? 171 PHE A CD1  1 
ATOM   1224 C  CD2  . PHE A 1 171 ? 93.282  88.960  116.315 1.00 57.58  ? 171 PHE A CD2  1 
ATOM   1225 C  CE1  . PHE A 1 171 ? 92.624  86.474  117.249 1.00 57.58  ? 171 PHE A CE1  1 
ATOM   1226 C  CE2  . PHE A 1 171 ? 94.084  88.345  117.239 1.00 57.58  ? 171 PHE A CE2  1 
ATOM   1227 C  CZ   . PHE A 1 171 ? 93.754  87.101  117.704 1.00 57.58  ? 171 PHE A CZ   1 
ATOM   1228 N  N    . TYR A 1 172 ? 91.298  91.945  115.790 1.00 52.88  ? 172 TYR A N    1 
ATOM   1229 C  CA   . TYR A 1 172 ? 91.851  93.011  116.610 1.00 52.88  ? 172 TYR A CA   1 
ATOM   1230 C  C    . TYR A 1 172 ? 90.766  93.675  117.434 1.00 52.88  ? 172 TYR A C    1 
ATOM   1231 O  O    . TYR A 1 172 ? 90.931  93.863  118.648 1.00 52.88  ? 172 TYR A O    1 
ATOM   1232 C  CB   . TYR A 1 172 ? 92.547  94.040  115.738 1.00 52.88  ? 172 TYR A CB   1 
ATOM   1233 C  CG   . TYR A 1 172 ? 93.679  94.710  116.436 1.00 52.88  ? 172 TYR A CG   1 
ATOM   1234 C  CD1  . TYR A 1 172 ? 94.883  94.062  116.603 1.00 52.88  ? 172 TYR A CD1  1 
ATOM   1235 C  CD2  . TYR A 1 172 ? 93.545  95.983  116.939 1.00 52.88  ? 172 TYR A CD2  1 
ATOM   1236 C  CE1  . TYR A 1 172 ? 95.927  94.665  117.244 1.00 52.88  ? 172 TYR A CE1  1 
ATOM   1237 C  CE2  . TYR A 1 172 ? 94.583  96.596  117.581 1.00 52.88  ? 172 TYR A CE2  1 
ATOM   1238 C  CZ   . TYR A 1 172 ? 95.773  95.932  117.730 1.00 52.88  ? 172 TYR A CZ   1 
ATOM   1239 O  OH   . TYR A 1 172 ? 96.817  96.539  118.375 1.00 52.88  ? 172 TYR A OH   1 
ATOM   1240 N  N    . CYS A 1 173 ? 89.617  93.953  116.808 1.00 63.49  ? 173 CYS A N    1 
ATOM   1241 C  CA   . CYS A 1 173 ? 88.514  94.574  117.529 1.00 63.49  ? 173 CYS A CA   1 
ATOM   1242 C  C    . CYS A 1 173 ? 88.115  93.734  118.726 1.00 63.49  ? 173 CYS A C    1 
ATOM   1243 O  O    . CYS A 1 173 ? 87.910  94.271  119.819 1.00 63.49  ? 173 CYS A O    1 
ATOM   1244 C  CB   . CYS A 1 173 ? 87.320  94.786  116.611 1.00 63.49  ? 173 CYS A CB   1 
ATOM   1245 S  SG   . CYS A 1 173 ? 87.493  96.180  115.501 1.00 63.49  ? 173 CYS A SG   1 
ATOM   1246 N  N    . ALA A 1 174 ? 88.083  92.409  118.553 1.00 63.47  ? 174 ALA A N    1 
ATOM   1247 C  CA   . ALA A 1 174 ? 87.736  91.539  119.666 1.00 63.47  ? 174 ALA A CA   1 
ATOM   1248 C  C    . ALA A 1 174 ? 88.685  91.763  120.828 1.00 63.47  ? 174 ALA A C    1 
ATOM   1249 O  O    . ALA A 1 174 ? 88.253  92.074  121.943 1.00 63.47  ? 174 ALA A O    1 
ATOM   1250 C  CB   . ALA A 1 174 ? 87.756  90.080  119.224 1.00 63.47  ? 174 ALA A CB   1 
ATOM   1251 N  N    . HIS A 1 175 ? 89.988  91.724  120.556 1.00 59.78  ? 175 HIS A N    1 
ATOM   1252 C  CA   . HIS A 1 175 ? 90.924  91.959  121.643 1.00 59.78  ? 175 HIS A CA   1 
ATOM   1253 C  C    . HIS A 1 175 ? 90.867  93.402  122.106 1.00 59.78  ? 175 HIS A C    1 
ATOM   1254 O  O    . HIS A 1 175 ? 91.012  93.668  123.306 1.00 59.78  ? 175 HIS A O    1 
ATOM   1255 C  CB   . HIS A 1 175 ? 92.328  91.557  121.226 1.00 59.78  ? 175 HIS A CB   1 
ATOM   1256 C  CG   . HIS A 1 175 ? 92.647  90.138  121.552 1.00 59.78  ? 175 HIS A CG   1 
ATOM   1257 N  ND1  . HIS A 1 175 ? 92.817  89.701  122.845 1.00 59.78  ? 175 HIS A ND1  1 
ATOM   1258 C  CD2  . HIS A 1 175 ? 92.803  89.053  120.762 1.00 59.78  ? 175 HIS A CD2  1 
ATOM   1259 C  CE1  . HIS A 1 175 ? 93.078  88.408  122.838 1.00 59.78  ? 175 HIS A CE1  1 
ATOM   1260 N  NE2  . HIS A 1 175 ? 93.075  87.989  121.586 1.00 59.78  ? 175 HIS A NE2  1 
ATOM   1261 N  N    . TRP A 1 176 ? 90.571  94.328  121.192 1.00 65.98  ? 176 TRP A N    1 
ATOM   1262 C  CA   . TRP A 1 176 ? 90.357  95.711  121.590 1.00 65.98  ? 176 TRP A CA   1 
ATOM   1263 C  C    . TRP A 1 176 ? 89.230  95.799  122.601 1.00 65.98  ? 176 TRP A C    1 
ATOM   1264 O  O    . TRP A 1 176 ? 89.349  96.498  123.615 1.00 65.98  ? 176 TRP A O    1 
ATOM   1265 C  CB   . TRP A 1 176 ? 90.049  96.556  120.359 1.00 65.98  ? 176 TRP A CB   1 
ATOM   1266 C  CG   . TRP A 1 176 ? 90.334  97.994  120.520 1.00 65.98  ? 176 TRP A CG   1 
ATOM   1267 C  CD1  . TRP A 1 176 ? 90.930  98.594  121.576 1.00 65.98  ? 176 TRP A CD1  1 
ATOM   1268 C  CD2  . TRP A 1 176 ? 90.042  99.026  119.581 1.00 65.98  ? 176 TRP A CD2  1 
ATOM   1269 N  NE1  . TRP A 1 176 ? 91.031  99.942  121.359 1.00 65.98  ? 176 TRP A NE1  1 
ATOM   1270 C  CE2  . TRP A 1 176 ? 90.489  100.232 120.136 1.00 65.98  ? 176 TRP A CE2  1 
ATOM   1271 C  CE3  . TRP A 1 176 ? 89.443  99.047  118.322 1.00 65.98  ? 176 TRP A CE3  1 
ATOM   1272 C  CZ2  . TRP A 1 176 ? 90.357  101.444 119.481 1.00 65.98  ? 176 TRP A CZ2  1 
ATOM   1273 C  CZ3  . TRP A 1 176 ? 89.311  100.250 117.673 1.00 65.98  ? 176 TRP A CZ3  1 
ATOM   1274 C  CH2  . TRP A 1 176 ? 89.764  101.434 118.251 1.00 65.98  ? 176 TRP A CH2  1 
ATOM   1275 N  N    . GLN A 1 177 ? 88.160  95.031  122.371 1.00 74.99  ? 177 GLN A N    1 
ATOM   1276 C  CA   . GLN A 1 177 ? 87.063  94.948  123.327 1.00 74.99  ? 177 GLN A CA   1 
ATOM   1277 C  C    . GLN A 1 177 ? 87.574  94.547  124.696 1.00 74.99  ? 177 GLN A C    1 
ATOM   1278 O  O    . GLN A 1 177 ? 87.300  95.221  125.699 1.00 74.99  ? 177 GLN A O    1 
ATOM   1279 C  CB   . GLN A 1 177 ? 86.030  93.946  122.824 1.00 74.99  ? 177 GLN A CB   1 
ATOM   1280 C  CG   . GLN A 1 177 ? 84.643  94.177  123.334 1.00 74.99  ? 177 GLN A CG   1 
ATOM   1281 C  CD   . GLN A 1 177 ? 84.297  93.282  124.500 1.00 74.99  ? 177 GLN A CD   1 
ATOM   1282 O  OE1  . GLN A 1 177 ? 84.901  92.227  124.689 1.00 74.99  ? 177 GLN A OE1  1 
ATOM   1283 N  NE2  . GLN A 1 177 ? 83.319  93.699  125.294 1.00 74.99  ? 177 GLN A NE2  1 
ATOM   1284 N  N    . THR A 1 178 ? 88.396  93.494  124.740 1.00 74.10  ? 178 THR A N    1 
ATOM   1285 C  CA   . THR A 1 178 ? 88.929  93.022  126.010 1.00 74.10  ? 178 THR A CA   1 
ATOM   1286 C  C    . THR A 1 178 ? 89.754  94.105  126.683 1.00 74.10  ? 178 THR A C    1 
ATOM   1287 O  O    . THR A 1 178 ? 89.669  94.292  127.904 1.00 74.10  ? 178 THR A O    1 
ATOM   1288 C  CB   . THR A 1 178 ? 89.761  91.763  125.781 1.00 74.10  ? 178 THR A CB   1 
ATOM   1289 O  OG1  . THR A 1 178 ? 88.932  90.749  125.207 1.00 74.10  ? 178 THR A OG1  1 
ATOM   1290 C  CG2  . THR A 1 178 ? 90.320  91.256  127.084 1.00 74.10  ? 178 THR A CG2  1 
ATOM   1291 N  N    . TYR A 1 179 ? 90.475  94.898  125.887 1.00 73.43  ? 179 TYR A N    1 
ATOM   1292 C  CA   . TYR A 1 179 ? 91.336  95.928  126.446 1.00 73.43  ? 179 TYR A CA   1 
ATOM   1293 C  C    . TYR A 1 179 ? 90.562  96.995  127.191 1.00 73.43  ? 179 TYR A C    1 
ATOM   1294 O  O    . TYR A 1 179 ? 91.149  97.700  128.015 1.00 73.43  ? 179 TYR A O    1 
ATOM   1295 C  CB   . TYR A 1 179 ? 92.166  96.575  125.347 1.00 73.43  ? 179 TYR A CB   1 
ATOM   1296 C  CG   . TYR A 1 179 ? 93.286  97.431  125.866 1.00 73.43  ? 179 TYR A CG   1 
ATOM   1297 C  CD1  . TYR A 1 179 ? 94.313  96.884  126.606 1.00 73.43  ? 179 TYR A CD1  1 
ATOM   1298 C  CD2  . TYR A 1 179 ? 93.312  98.786  125.616 1.00 73.43  ? 179 TYR A CD2  1 
ATOM   1299 C  CE1  . TYR A 1 179 ? 95.337  97.668  127.078 1.00 73.43  ? 179 TYR A CE1  1 
ATOM   1300 C  CE2  . TYR A 1 179 ? 94.330  99.574  126.077 1.00 73.43  ? 179 TYR A CE2  1 
ATOM   1301 C  CZ   . TYR A 1 179 ? 95.334  99.014  126.812 1.00 73.43  ? 179 TYR A CZ   1 
ATOM   1302 O  OH   . TYR A 1 179 ? 96.352  99.808  127.273 1.00 73.43  ? 179 TYR A OH   1 
ATOM   1303 N  N    . VAL A 1 180 ? 89.263  97.136  126.941 1.00 78.51  ? 180 VAL A N    1 
ATOM   1304 C  CA   . VAL A 1 180 ? 88.484  98.113  127.683 1.00 78.51  ? 180 VAL A CA   1 
ATOM   1305 C  C    . VAL A 1 180 ? 87.439  97.449  128.559 1.00 78.51  ? 180 VAL A C    1 
ATOM   1306 O  O    . VAL A 1 180 ? 86.580  98.136  129.119 1.00 78.51  ? 180 VAL A O    1 
ATOM   1307 C  CB   . VAL A 1 180 ? 87.849  99.149  126.748 1.00 78.51  ? 180 VAL A CB   1 
ATOM   1308 C  CG1  . VAL A 1 180 ? 88.932  99.913  126.021 1.00 78.51  ? 180 VAL A CG1  1 
ATOM   1309 C  CG2  . VAL A 1 180 ? 86.926  98.468  125.776 1.00 78.51  ? 180 VAL A CG2  1 
ATOM   1310 N  N    . SER A 1 181 ? 87.481  96.126  128.690 1.00 82.36  ? 181 SER A N    1 
ATOM   1311 C  CA   . SER A 1 181 ? 86.581  95.466  129.628 1.00 82.36  ? 181 SER A CA   1 
ATOM   1312 C  C    . SER A 1 181 ? 87.239  94.395  130.473 1.00 82.36  ? 181 SER A C    1 
ATOM   1313 O  O    . SER A 1 181 ? 86.627  93.956  131.450 1.00 82.36  ? 181 SER A O    1 
ATOM   1314 C  CB   . SER A 1 181 ? 85.393  94.845  128.894 1.00 82.36  ? 181 SER A CB   1 
ATOM   1315 O  OG   . SER A 1 181 ? 84.481  94.287  129.821 1.00 82.36  ? 181 SER A OG   1 
ATOM   1316 N  N    . GLY A 1 182 ? 88.440  93.936  130.137 1.00 87.76  ? 182 GLY A N    1 
ATOM   1317 C  CA   . GLY A 1 182 ? 89.105  92.918  130.916 1.00 87.76  ? 182 GLY A CA   1 
ATOM   1318 C  C    . GLY A 1 182 ? 88.518  91.533  130.790 1.00 87.76  ? 182 GLY A C    1 
ATOM   1319 O  O    . GLY A 1 182 ? 89.029  90.604  131.419 1.00 87.76  ? 182 GLY A O    1 
ATOM   1320 N  N    . MET A 1 183 ? 87.468  91.365  129.990 1.00 96.43  ? 183 MET A N    1 
ATOM   1321 C  CA   . MET A 1 183 ? 86.794  90.089  129.833 1.00 96.43  ? 183 MET A CA   1 
ATOM   1322 C  C    . MET A 1 183 ? 86.333  89.958  128.393 1.00 96.43  ? 183 MET A C    1 
ATOM   1323 O  O    . MET A 1 183 ? 85.857  90.927  127.797 1.00 96.43  ? 183 MET A O    1 
ATOM   1324 C  CB   . MET A 1 183 ? 85.601  89.966  130.789 1.00 96.43  ? 183 MET A CB   1 
ATOM   1325 C  CG   . MET A 1 183 ? 84.797  91.247  130.932 1.00 96.43  ? 183 MET A CG   1 
ATOM   1326 S  SD   . MET A 1 183 ? 83.202  90.997  131.738 1.00 96.43  ? 183 MET A SD   1 
ATOM   1327 C  CE   . MET A 1 183 ? 82.138  90.737  130.323 1.00 96.43  ? 183 MET A CE   1 
ATOM   1328 N  N    . LEU A 1 184 ? 86.474  88.760  127.841 1.00 99.37  ? 184 LEU A N    1 
ATOM   1329 C  CA   . LEU A 1 184 ? 86.164  88.536  126.437 1.00 99.37  ? 184 LEU A CA   1 
ATOM   1330 C  C    . LEU A 1 184 ? 84.663  88.336  126.276 1.00 99.37  ? 184 LEU A C    1 
ATOM   1331 O  O    . LEU A 1 184 ? 84.096  87.395  126.841 1.00 99.37  ? 184 LEU A O    1 
ATOM   1332 C  CB   . LEU A 1 184 ? 86.926  87.325  125.904 1.00 99.37  ? 184 LEU A CB   1 
ATOM   1333 C  CG   . LEU A 1 184 ? 88.409  87.451  125.540 1.00 99.37  ? 184 LEU A CG   1 
ATOM   1334 C  CD1  . LEU A 1 184 ? 89.294  87.489  126.777 1.00 99.37  ? 184 LEU A CD1  1 
ATOM   1335 C  CD2  . LEU A 1 184 ? 88.838  86.319  124.620 1.00 99.37  ? 184 LEU A CD2  1 
ATOM   1336 N  N    . ARG A 1 185 ? 84.023  89.221  125.523 1.00 101.12 ? 185 ARG A N    1 
ATOM   1337 C  CA   . ARG A 1 185 ? 82.623  89.076  125.154 1.00 101.12 ? 185 ARG A CA   1 
ATOM   1338 C  C    . ARG A 1 185 ? 82.571  88.543  123.731 1.00 101.12 ? 185 ARG A C    1 
ATOM   1339 O  O    . ARG A 1 185 ? 83.137  89.155  122.820 1.00 101.12 ? 185 ARG A O    1 
ATOM   1340 C  CB   . ARG A 1 185 ? 81.878  90.405  125.267 1.00 101.12 ? 185 ARG A CB   1 
ATOM   1341 C  CG   . ARG A 1 185 ? 81.541  90.803  126.690 1.00 101.12 ? 185 ARG A CG   1 
ATOM   1342 C  CD   . ARG A 1 185 ? 80.762  92.110  126.741 1.00 101.12 ? 185 ARG A CD   1 
ATOM   1343 N  NE   . ARG A 1 185 ? 79.441  91.982  126.135 1.00 101.12 ? 185 ARG A NE   1 
ATOM   1344 C  CZ   . ARG A 1 185 ? 78.299  92.113  126.799 1.00 101.12 ? 185 ARG A CZ   1 
ATOM   1345 N  NH1  . ARG A 1 185 ? 78.311  92.375  128.097 1.00 101.12 ? 185 ARG A NH1  1 
ATOM   1346 N  NH2  . ARG A 1 185 ? 77.142  91.978  126.167 1.00 101.12 ? 185 ARG A NH2  1 
ATOM   1347 N  N    . PHE A 1 186 ? 81.910  87.404  123.541 1.00 101.27 ? 186 PHE A N    1 
ATOM   1348 C  CA   . PHE A 1 186 ? 81.922  86.772  122.227 1.00 101.27 ? 186 PHE A CA   1 
ATOM   1349 C  C    . PHE A 1 186 ? 80.892  87.393  121.293 1.00 101.27 ? 186 PHE A C    1 
ATOM   1350 O  O    . PHE A 1 186 ? 81.245  87.991  120.270 1.00 101.27 ? 186 PHE A O    1 
ATOM   1351 C  CB   . PHE A 1 186 ? 81.683  85.271  122.370 1.00 101.27 ? 186 PHE A CB   1 
ATOM   1352 C  CG   . PHE A 1 186 ? 82.906  84.501  122.778 1.00 101.27 ? 186 PHE A CG   1 
ATOM   1353 C  CD1  . PHE A 1 186 ? 84.160  85.079  122.718 1.00 101.27 ? 186 PHE A CD1  1 
ATOM   1354 C  CD2  . PHE A 1 186 ? 82.805  83.184  123.194 1.00 101.27 ? 186 PHE A CD2  1 
ATOM   1355 C  CE1  . PHE A 1 186 ? 85.283  84.368  123.078 1.00 101.27 ? 186 PHE A CE1  1 
ATOM   1356 C  CE2  . PHE A 1 186 ? 83.927  82.471  123.558 1.00 101.27 ? 186 PHE A CE2  1 
ATOM   1357 C  CZ   . PHE A 1 186 ? 85.165  83.064  123.500 1.00 101.27 ? 186 PHE A CZ   1 
ATOM   1358 N  N    . GLY A 1 187 ? 79.620  87.274  121.633 1.00 101.59 ? 187 GLY A N    1 
ATOM   1359 C  CA   . GLY A 1 187 ? 78.543  87.722  120.776 1.00 101.59 ? 187 GLY A CA   1 
ATOM   1360 C  C    . GLY A 1 187 ? 77.774  86.557  120.177 1.00 101.59 ? 187 GLY A C    1 
ATOM   1361 O  O    . GLY A 1 187 ? 78.181  85.396  120.241 1.00 101.59 ? 187 GLY A O    1 
ATOM   1362 N  N    . LYS A 1 188 ? 76.635  86.904  119.572 1.00 102.97 ? 188 LYS A N    1 
ATOM   1363 C  CA   . LYS A 1 188 ? 75.712  85.901  119.057 1.00 102.97 ? 188 LYS A CA   1 
ATOM   1364 C  C    . LYS A 1 188 ? 76.240  85.191  117.821 1.00 102.97 ? 188 LYS A C    1 
ATOM   1365 O  O    . LYS A 1 188 ? 75.754  84.103  117.493 1.00 102.97 ? 188 LYS A O    1 
ATOM   1366 C  CB   . LYS A 1 188 ? 74.360  86.555  118.771 1.00 102.97 ? 188 LYS A CB   1 
ATOM   1367 C  CG   . LYS A 1 188 ? 73.518  86.773  120.017 1.00 102.97 ? 188 LYS A CG   1 
ATOM   1368 C  CD   . LYS A 1 188 ? 72.621  87.993  119.890 1.00 102.97 ? 188 LYS A CD   1 
ATOM   1369 C  CE   . LYS A 1 188 ? 72.215  88.524  121.257 1.00 102.97 ? 188 LYS A CE   1 
ATOM   1370 N  NZ   . LYS A 1 188 ? 71.949  89.988  121.246 1.00 102.97 ? 188 LYS A NZ   1 
ATOM   1371 N  N    . VAL A 1 189 ? 77.209  85.774  117.129 1.00 97.05  ? 189 VAL A N    1 
ATOM   1372 C  CA   . VAL A 1 189 ? 77.896  85.095  116.041 1.00 97.05  ? 189 VAL A CA   1 
ATOM   1373 C  C    . VAL A 1 189 ? 79.389  85.303  116.269 1.00 97.05  ? 189 VAL A C    1 
ATOM   1374 O  O    . VAL A 1 189 ? 79.823  86.416  116.590 1.00 97.05  ? 189 VAL A O    1 
ATOM   1375 C  CB   . VAL A 1 189 ? 77.426  85.595  114.659 1.00 97.05  ? 189 VAL A CB   1 
ATOM   1376 C  CG1  . VAL A 1 189 ? 78.548  86.175  113.823 1.00 97.05  ? 189 VAL A CG1  1 
ATOM   1377 C  CG2  . VAL A 1 189 ? 76.713  84.480  113.913 1.00 97.05  ? 189 VAL A CG2  1 
ATOM   1378 N  N    . ASP A 1 190 ? 80.154  84.225  116.212 1.00 95.45  ? 190 ASP A N    1 
ATOM   1379 C  CA   . ASP A 1 190 ? 81.535  84.290  116.664 1.00 95.45  ? 190 ASP A CA   1 
ATOM   1380 C  C    . ASP A 1 190 ? 82.353  83.224  115.936 1.00 95.45  ? 190 ASP A C    1 
ATOM   1381 O  O    . ASP A 1 190 ? 81.976  82.763  114.853 1.00 95.45  ? 190 ASP A O    1 
ATOM   1382 C  CB   . ASP A 1 190 ? 81.616  84.154  118.193 1.00 95.45  ? 190 ASP A CB   1 
ATOM   1383 C  CG   . ASP A 1 190 ? 82.889  84.753  118.756 1.00 95.45  ? 190 ASP A CG   1 
ATOM   1384 O  OD1  . ASP A 1 190 ? 83.468  85.637  118.090 1.00 95.45  ? 190 ASP A OD1  1 
ATOM   1385 O  OD2  . ASP A 1 190 ? 83.337  84.305  119.821 1.00 95.45  ? 190 ASP A OD2  1 
ATOM   1386 N  N    . VAL A 1 191 ? 83.479  82.851  116.544 1.00 86.50  ? 191 VAL A N    1 
ATOM   1387 C  CA   . VAL A 1 191 ? 84.553  82.110  115.891 1.00 86.50  ? 191 VAL A CA   1 
ATOM   1388 C  C    . VAL A 1 191 ? 84.067  80.768  115.373 1.00 86.50  ? 191 VAL A C    1 
ATOM   1389 O  O    . VAL A 1 191 ? 84.501  80.306  114.312 1.00 86.50  ? 191 VAL A O    1 
ATOM   1390 C  CB   . VAL A 1 191 ? 85.716  81.926  116.876 1.00 86.50  ? 191 VAL A CB   1 
ATOM   1391 C  CG1  . VAL A 1 191 ? 86.919  81.342  116.182 1.00 86.50  ? 191 VAL A CG1  1 
ATOM   1392 C  CG2  . VAL A 1 191 ? 86.036  83.235  117.533 1.00 86.50  ? 191 VAL A CG2  1 
ATOM   1393 N  N    . THR A 1 192 ? 83.184  80.110  116.123 1.00 92.87  ? 192 THR A N    1 
ATOM   1394 C  CA   . THR A 1 192 ? 82.708  78.796  115.709 1.00 92.87  ? 192 THR A CA   1 
ATOM   1395 C  C    . THR A 1 192 ? 81.937  78.874  114.396 1.00 92.87  ? 192 THR A C    1 
ATOM   1396 O  O    . THR A 1 192 ? 82.057  77.983  113.546 1.00 92.87  ? 192 THR A O    1 
ATOM   1397 C  CB   . THR A 1 192 ? 81.855  78.185  116.811 1.00 92.87  ? 192 THR A CB   1 
ATOM   1398 O  OG1  . THR A 1 192 ? 80.741  79.044  117.082 1.00 92.87  ? 192 THR A OG1  1 
ATOM   1399 C  CG2  . THR A 1 192 ? 82.686  78.017  118.069 1.00 92.87  ? 192 THR A CG2  1 
ATOM   1400 N  N    . GLU A 1 193 ? 81.159  79.942  114.205 1.00 95.69  ? 193 GLU A N    1 
ATOM   1401 C  CA   . GLU A 1 193 ? 80.433  80.121  112.952 1.00 95.69  ? 193 GLU A CA   1 
ATOM   1402 C  C    . GLU A 1 193 ? 81.384  80.282  111.770 1.00 95.69  ? 193 GLU A C    1 
ATOM   1403 O  O    . GLU A 1 193 ? 81.188  79.656  110.724 1.00 95.69  ? 193 GLU A O    1 
ATOM   1404 C  CB   . GLU A 1 193 ? 79.496  81.322  113.062 1.00 95.69  ? 193 GLU A CB   1 
ATOM   1405 C  CG   . GLU A 1 193 ? 78.236  81.041  113.858 1.00 95.69  ? 193 GLU A CG   1 
ATOM   1406 C  CD   . GLU A 1 193 ? 78.453  81.165  115.352 1.00 95.69  ? 193 GLU A CD   1 
ATOM   1407 O  OE1  . GLU A 1 193 ? 79.583  81.488  115.767 1.00 95.69  ? 193 GLU A OE1  1 
ATOM   1408 O  OE2  . GLU A 1 193 ? 77.489  80.939  116.117 1.00 95.69  ? 193 GLU A OE2  1 
ATOM   1409 N  N    . ILE A 1 194 ? 82.425  81.104  111.923 1.00 86.88  ? 194 ILE A N    1 
ATOM   1410 C  CA   . ILE A 1 194 ? 83.402  81.265  110.850 1.00 86.88  ? 194 ILE A CA   1 
ATOM   1411 C  C    . ILE A 1 194 ? 84.111  79.952  110.573 1.00 86.88  ? 194 ILE A C    1 
ATOM   1412 O  O    . ILE A 1 194 ? 84.333  79.580  109.418 1.00 86.88  ? 194 ILE A O    1 
ATOM   1413 C  CB   . ILE A 1 194 ? 84.417  82.367  111.188 1.00 86.88  ? 194 ILE A CB   1 
ATOM   1414 C  CG1  . ILE A 1 194 ? 83.734  83.712  111.295 1.00 86.88  ? 194 ILE A CG1  1 
ATOM   1415 C  CG2  . ILE A 1 194 ? 85.502  82.439  110.135 1.00 86.88  ? 194 ILE A CG2  1 
ATOM   1416 C  CD1  . ILE A 1 194 ? 84.640  84.746  111.838 1.00 86.88  ? 194 ILE A CD1  1 
ATOM   1417 N  N    . GLN A 1 195 ? 84.500  79.241  111.627 1.00 86.45  ? 195 GLN A N    1 
ATOM   1418 C  CA   . GLN A 1 195 ? 85.262  78.018  111.432 1.00 86.45  ? 195 GLN A CA   1 
ATOM   1419 C  C    . GLN A 1 195 ? 84.429  76.951  110.731 1.00 86.45  ? 195 GLN A C    1 
ATOM   1420 O  O    . GLN A 1 195 ? 84.924  76.276  109.817 1.00 86.45  ? 195 GLN A O    1 
ATOM   1421 C  CB   . GLN A 1 195 ? 85.798  77.521  112.772 1.00 86.45  ? 195 GLN A CB   1 
ATOM   1422 C  CG   . GLN A 1 195 ? 87.066  78.247  113.205 1.00 86.45  ? 195 GLN A CG   1 
ATOM   1423 C  CD   . GLN A 1 195 ? 87.323  78.158  114.697 1.00 86.45  ? 195 GLN A CD   1 
ATOM   1424 O  OE1  . GLN A 1 195 ? 86.462  77.732  115.462 1.00 86.45  ? 195 GLN A OE1  1 
ATOM   1425 N  NE2  . GLN A 1 195 ? 88.516  78.558  115.113 1.00 86.45  ? 195 GLN A NE2  1 
ATOM   1426 N  N    . ILE A 1 196 ? 83.155  76.803  111.106 1.00 86.53  ? 196 ILE A N    1 
ATOM   1427 C  CA   . ILE A 1 196 ? 82.326  75.824  110.412 1.00 86.53  ? 196 ILE A CA   1 
ATOM   1428 C  C    . ILE A 1 196 ? 82.034  76.284  108.986 1.00 86.53  ? 196 ILE A C    1 
ATOM   1429 O  O    . ILE A 1 196 ? 81.997  75.467  108.062 1.00 86.53  ? 196 ILE A O    1 
ATOM   1430 C  CB   . ILE A 1 196 ? 81.037  75.502  111.193 1.00 86.53  ? 196 ILE A CB   1 
ATOM   1431 C  CG1  . ILE A 1 196 ? 80.112  76.711  111.301 1.00 86.53  ? 196 ILE A CG1  1 
ATOM   1432 C  CG2  . ILE A 1 196 ? 81.379  74.945  112.563 1.00 86.53  ? 196 ILE A CG2  1 
ATOM   1433 C  CD1  . ILE A 1 196 ? 78.669  76.350  111.573 1.00 86.53  ? 196 ILE A CD1  1 
ATOM   1434 N  N    . ALA A 1 197 ? 81.861  77.592  108.771 1.00 84.02  ? 197 ALA A N    1 
ATOM   1435 C  CA   . ALA A 1 197 ? 81.630  78.076  107.415 1.00 84.02  ? 197 ALA A CA   1 
ATOM   1436 C  C    . ALA A 1 197 ? 82.845  77.836  106.530 1.00 84.02  ? 197 ALA A C    1 
ATOM   1437 O  O    . ALA A 1 197 ? 82.707  77.494  105.350 1.00 84.02  ? 197 ALA A O    1 
ATOM   1438 C  CB   . ALA A 1 197 ? 81.268  79.558  107.441 1.00 84.02  ? 197 ALA A CB   1 
ATOM   1439 N  N    . LEU A 1 198 ? 84.040  77.987  107.085 1.00 82.97  ? 198 LEU A N    1 
ATOM   1440 C  CA   . LEU A 1 198 ? 85.240  77.795  106.291 1.00 82.97  ? 198 LEU A CA   1 
ATOM   1441 C  C    . LEU A 1 198 ? 85.527  76.326  106.043 1.00 82.97  ? 198 LEU A C    1 
ATOM   1442 O  O    . LEU A 1 198 ? 86.012  75.976  104.963 1.00 82.97  ? 198 LEU A O    1 
ATOM   1443 C  CB   . LEU A 1 198 ? 86.431  78.485  106.949 1.00 82.97  ? 198 LEU A CB   1 
ATOM   1444 C  CG   . LEU A 1 198 ? 86.322  80.012  106.895 1.00 82.97  ? 198 LEU A CG   1 
ATOM   1445 C  CD1  . LEU A 1 198 ? 87.638  80.678  107.219 1.00 82.97  ? 198 LEU A CD1  1 
ATOM   1446 C  CD2  . LEU A 1 198 ? 85.799  80.488  105.551 1.00 82.97  ? 198 LEU A CD2  1 
ATOM   1447 N  N    . VAL A 1 199 ? 85.215  75.440  106.991 1.00 81.43  ? 199 VAL A N    1 
ATOM   1448 C  CA   . VAL A 1 199 ? 85.378  74.031  106.648 1.00 81.43  ? 199 VAL A CA   1 
ATOM   1449 C  C    . VAL A 1 199 ? 84.312  73.616  105.637 1.00 81.43  ? 199 VAL A C    1 
ATOM   1450 O  O    . VAL A 1 199 ? 84.563  72.751  104.790 1.00 81.43  ? 199 VAL A O    1 
ATOM   1451 C  CB   . VAL A 1 199 ? 85.392  73.135  107.905 1.00 81.43  ? 199 VAL A CB   1 
ATOM   1452 C  CG1  . VAL A 1 199 ? 84.067  73.147  108.623 1.00 81.43  ? 199 VAL A CG1  1 
ATOM   1453 C  CG2  . VAL A 1 199 ? 85.819  71.717  107.554 1.00 81.43  ? 199 VAL A CG2  1 
ATOM   1454 N  N    . ILE A 1 200 ? 83.139  74.263  105.661 1.00 84.07  ? 200 ILE A N    1 
ATOM   1455 C  CA   . ILE A 1 200 ? 82.124  74.005  104.638 1.00 84.07  ? 200 ILE A CA   1 
ATOM   1456 C  C    . ILE A 1 200 ? 82.611  74.449  103.262 1.00 84.07  ? 200 ILE A C    1 
ATOM   1457 O  O    . ILE A 1 200 ? 82.474  73.714  102.277 1.00 84.07  ? 200 ILE A O    1 
ATOM   1458 C  CB   . ILE A 1 200 ? 80.792  74.679  105.013 1.00 84.07  ? 200 ILE A CB   1 
ATOM   1459 C  CG1  . ILE A 1 200 ? 80.077  73.883  106.101 1.00 84.07  ? 200 ILE A CG1  1 
ATOM   1460 C  CG2  . ILE A 1 200 ? 79.890  74.831  103.803 1.00 84.07  ? 200 ILE A CG2  1 
ATOM   1461 C  CD1  . ILE A 1 200 ? 78.896  74.605  106.698 1.00 84.07  ? 200 ILE A CD1  1 
ATOM   1462 N  N    . VAL A 1 201 ? 83.193  75.650  103.167 1.00 84.19  ? 201 VAL A N    1 
ATOM   1463 C  CA   . VAL A 1 201 ? 83.647  76.107  101.853 1.00 84.19  ? 201 VAL A CA   1 
ATOM   1464 C  C    . VAL A 1 201 ? 84.826  75.263  101.386 1.00 84.19  ? 201 VAL A C    1 
ATOM   1465 O  O    . VAL A 1 201 ? 84.958  74.977  100.189 1.00 84.19  ? 201 VAL A O    1 
ATOM   1466 C  CB   . VAL A 1 201 ? 83.972  77.619  101.851 1.00 84.19  ? 201 VAL A CB   1 
ATOM   1467 C  CG1  . VAL A 1 201 ? 85.126  77.954  102.733 1.00 84.19  ? 201 VAL A CG1  1 
ATOM   1468 C  CG2  . VAL A 1 201 ? 84.270  78.103  100.461 1.00 84.19  ? 201 VAL A CG2  1 
ATOM   1469 N  N    . PHE A 1 202 ? 85.656  74.789  102.314 1.00 82.81  ? 202 PHE A N    1 
ATOM   1470 C  CA   . PHE A 1 202 ? 86.756  73.910  101.943 1.00 82.81  ? 202 PHE A CA   1 
ATOM   1471 C  C    . PHE A 1 202 ? 86.246  72.587  101.386 1.00 82.81  ? 202 PHE A C    1 
ATOM   1472 O  O    . PHE A 1 202 ? 86.686  72.147  100.320 1.00 82.81  ? 202 PHE A O    1 
ATOM   1473 C  CB   . PHE A 1 202 ? 87.652  73.669  103.148 1.00 82.81  ? 202 PHE A CB   1 
ATOM   1474 C  CG   . PHE A 1 202 ? 88.803  74.612  103.241 1.00 82.81  ? 202 PHE A CG   1 
ATOM   1475 C  CD1  . PHE A 1 202 ? 88.605  75.967  103.108 1.00 82.81  ? 202 PHE A CD1  1 
ATOM   1476 C  CD2  . PHE A 1 202 ? 90.083  74.149  103.469 1.00 82.81  ? 202 PHE A CD2  1 
ATOM   1477 C  CE1  . PHE A 1 202 ? 89.653  76.835  103.198 1.00 82.81  ? 202 PHE A CE1  1 
ATOM   1478 C  CE2  . PHE A 1 202 ? 91.133  75.023  103.557 1.00 82.81  ? 202 PHE A CE2  1 
ATOM   1479 C  CZ   . PHE A 1 202 ? 90.920  76.368  103.421 1.00 82.81  ? 202 PHE A CZ   1 
ATOM   1480 N  N    . VAL A 1 203 ? 85.307  71.941  102.086 1.00 88.93  ? 203 VAL A N    1 
ATOM   1481 C  CA   . VAL A 1 203 ? 84.842  70.641  101.607 1.00 88.93  ? 203 VAL A CA   1 
ATOM   1482 C  C    . VAL A 1 203 ? 84.005  70.802  100.346 1.00 88.93  ? 203 VAL A C    1 
ATOM   1483 O  O    . VAL A 1 203 ? 83.946  69.889  99.513  1.00 88.93  ? 203 VAL A O    1 
ATOM   1484 C  CB   . VAL A 1 203 ? 84.065  69.878  102.698 1.00 88.93  ? 203 VAL A CB   1 
ATOM   1485 C  CG1  . VAL A 1 203 ? 84.975  69.544  103.871 1.00 88.93  ? 203 VAL A CG1  1 
ATOM   1486 C  CG2  . VAL A 1 203 ? 82.826  70.636  103.138 1.00 88.93  ? 203 VAL A CG2  1 
ATOM   1487 N  N    . LEU A 1 204 ? 83.363  71.958  100.171 1.00 90.08  ? 204 LEU A N    1 
ATOM   1488 C  CA   . LEU A 1 204 ? 82.590  72.191  98.960  1.00 90.08  ? 204 LEU A CA   1 
ATOM   1489 C  C    . LEU A 1 204 ? 83.514  72.378  97.766  1.00 90.08  ? 204 LEU A C    1 
ATOM   1490 O  O    . LEU A 1 204 ? 83.262  71.832  96.687  1.00 90.08  ? 204 LEU A O    1 
ATOM   1491 C  CB   . LEU A 1 204 ? 81.676  73.402  99.163  1.00 90.08  ? 204 LEU A CB   1 
ATOM   1492 C  CG   . LEU A 1 204 ? 80.412  73.645  98.324  1.00 90.08  ? 204 LEU A CG   1 
ATOM   1493 C  CD1  . LEU A 1 204 ? 79.656  74.827  98.900  1.00 90.08  ? 204 LEU A CD1  1 
ATOM   1494 C  CD2  . LEU A 1 204 ? 80.676  73.886  96.847  1.00 90.08  ? 204 LEU A CD2  1 
ATOM   1495 N  N    . SER A 1 205 ? 84.604  73.127  97.944  1.00 91.32  ? 205 SER A N    1 
ATOM   1496 C  CA   . SER A 1 205 ? 85.570  73.268  96.863  1.00 91.32  ? 205 SER A CA   1 
ATOM   1497 C  C    . SER A 1 205 ? 86.394  72.002  96.671  1.00 91.32  ? 205 SER A C    1 
ATOM   1498 O  O    . SER A 1 205 ? 87.060  71.858  95.642  1.00 91.32  ? 205 SER A O    1 
ATOM   1499 C  CB   . SER A 1 205 ? 86.486  74.460  97.125  1.00 91.32  ? 205 SER A CB   1 
ATOM   1500 O  OG   . SER A 1 205 ? 87.271  74.744  95.985  1.00 91.32  ? 205 SER A OG   1 
ATOM   1501 N  N    . ALA A 1 206 ? 86.370  71.091  97.641  1.00 94.15  ? 206 ALA A N    1 
ATOM   1502 C  CA   . ALA A 1 206 ? 87.067  69.822  97.482  1.00 94.15  ? 206 ALA A CA   1 
ATOM   1503 C  C    . ALA A 1 206 ? 86.230  68.822  96.698  1.00 94.15  ? 206 ALA A C    1 
ATOM   1504 O  O    . ALA A 1 206 ? 86.670  68.308  95.661  1.00 94.15  ? 206 ALA A O    1 
ATOM   1505 C  CB   . ALA A 1 206 ? 87.428  69.248  98.853  1.00 94.15  ? 206 ALA A CB   1 
ATOM   1506 N  N    . PHE A 1 207 ? 85.022  68.524  97.187  1.00 100.92 ? 207 PHE A N    1 
ATOM   1507 C  CA   . PHE A 1 207 ? 84.196  67.484  96.577  1.00 100.92 ? 207 PHE A CA   1 
ATOM   1508 C  C    . PHE A 1 207 ? 83.793  67.859  95.158  1.00 100.92 ? 207 PHE A C    1 
ATOM   1509 O  O    . PHE A 1 207 ? 83.916  67.052  94.232  1.00 100.92 ? 207 PHE A O    1 
ATOM   1510 C  CB   . PHE A 1 207 ? 82.960  67.222  97.437  1.00 100.92 ? 207 PHE A CB   1 
ATOM   1511 C  CG   . PHE A 1 207 ? 83.164  66.163  98.477  1.00 100.92 ? 207 PHE A CG   1 
ATOM   1512 C  CD1  . PHE A 1 207 ? 83.487  64.870  98.110  1.00 100.92 ? 207 PHE A CD1  1 
ATOM   1513 C  CD2  . PHE A 1 207 ? 83.033  66.461  99.823  1.00 100.92 ? 207 PHE A CD2  1 
ATOM   1514 C  CE1  . PHE A 1 207 ? 83.678  63.888  99.067  1.00 100.92 ? 207 PHE A CE1  1 
ATOM   1515 C  CE2  . PHE A 1 207 ? 83.221  65.486  100.783 1.00 100.92 ? 207 PHE A CE2  1 
ATOM   1516 C  CZ   . PHE A 1 207 ? 83.544  64.197  100.406 1.00 100.92 ? 207 PHE A CZ   1 
ATOM   1517 N  N    . GLY A 1 208 ? 83.311  69.081  94.972  1.00 103.22 ? 208 GLY A N    1 
ATOM   1518 C  CA   . GLY A 1 208 ? 83.065  69.589  93.640  1.00 103.22 ? 208 GLY A CA   1 
ATOM   1519 C  C    . GLY A 1 208 ? 84.264  70.337  93.095  1.00 103.22 ? 208 GLY A C    1 
ATOM   1520 O  O    . GLY A 1 208 ? 85.191  70.689  93.821  1.00 103.22 ? 208 GLY A O    1 
ATOM   1521 N  N    . GLY A 1 209 ? 84.243  70.563  91.784  1.00 106.77 ? 209 GLY A N    1 
ATOM   1522 C  CA   . GLY A 1 209 ? 85.274  71.371  91.167  1.00 106.77 ? 209 GLY A CA   1 
ATOM   1523 C  C    . GLY A 1 209 ? 85.195  72.814  91.625  1.00 106.77 ? 209 GLY A C    1 
ATOM   1524 O  O    . GLY A 1 209 ? 84.121  73.357  91.871  1.00 106.77 ? 209 GLY A O    1 
ATOM   1525 N  N    . ALA A 1 210 ? 86.364  73.445  91.748  1.00 103.90 ? 210 ALA A N    1 
ATOM   1526 C  CA   . ALA A 1 210 ? 86.408  74.833  92.187  1.00 103.90 ? 210 ALA A CA   1 
ATOM   1527 C  C    . ALA A 1 210 ? 85.872  75.784  91.125  1.00 103.90 ? 210 ALA A C    1 
ATOM   1528 O  O    . ALA A 1 210 ? 85.518  76.925  91.450  1.00 103.90 ? 210 ALA A O    1 
ATOM   1529 C  CB   . ALA A 1 210 ? 87.834  75.214  92.570  1.00 103.90 ? 210 ALA A CB   1 
ATOM   1530 N  N    . THR A 1 211 ? 85.771  75.327  89.874  1.00 109.92 ? 211 THR A N    1 
ATOM   1531 C  CA   . THR A 1 211 ? 85.259  76.163  88.796  1.00 109.92 ? 211 THR A CA   1 
ATOM   1532 C  C    . THR A 1 211 ? 83.809  76.572  89.007  1.00 109.92 ? 211 THR A C    1 
ATOM   1533 O  O    . THR A 1 211 ? 83.350  77.524  88.366  1.00 109.92 ? 211 THR A O    1 
ATOM   1534 C  CB   . THR A 1 211 ? 85.395  75.430  87.463  1.00 109.92 ? 211 THR A CB   1 
ATOM   1535 O  OG1  . THR A 1 211 ? 84.525  74.290  87.453  1.00 109.92 ? 211 THR A OG1  1 
ATOM   1536 C  CG2  . THR A 1 211 ? 86.826  74.968  87.260  1.00 109.92 ? 211 THR A CG2  1 
ATOM   1537 N  N    . MET A 1 212 ? 83.081  75.885  89.893  1.00 110.27 ? 212 MET A N    1 
ATOM   1538 C  CA   . MET A 1 212 ? 81.726  76.307  90.225  1.00 110.27 ? 212 MET A CA   1 
ATOM   1539 C  C    . MET A 1 212 ? 81.703  77.678  90.876  1.00 110.27 ? 212 MET A C    1 
ATOM   1540 O  O    . MET A 1 212 ? 80.662  78.344  90.854  1.00 110.27 ? 212 MET A O    1 
ATOM   1541 C  CB   . MET A 1 212 ? 81.044  75.249  91.114  1.00 110.27 ? 212 MET A CB   1 
ATOM   1542 C  CG   . MET A 1 212 ? 81.517  75.087  92.580  1.00 110.27 ? 212 MET A CG   1 
ATOM   1543 S  SD   . MET A 1 212 ? 81.277  76.410  93.790  1.00 110.27 ? 212 MET A SD   1 
ATOM   1544 C  CE   . MET A 1 212 ? 79.541  76.217  94.168  1.00 110.27 ? 212 MET A CE   1 
ATOM   1545 N  N    . TRP A 1 213 ? 82.818  78.114  91.462  1.00 104.65 ? 213 TRP A N    1 
ATOM   1546 C  CA   . TRP A 1 213 ? 82.876  79.468  91.989  1.00 104.65 ? 213 TRP A CA   1 
ATOM   1547 C  C    . TRP A 1 213 ? 82.873  80.522  90.893  1.00 104.65 ? 213 TRP A C    1 
ATOM   1548 O  O    . TRP A 1 213 ? 82.668  81.701  91.192  1.00 104.65 ? 213 TRP A O    1 
ATOM   1549 C  CB   . TRP A 1 213 ? 84.106  79.619  92.885  1.00 104.65 ? 213 TRP A CB   1 
ATOM   1550 C  CG   . TRP A 1 213 ? 84.025  78.752  94.099  1.00 104.65 ? 213 TRP A CG   1 
ATOM   1551 C  CD1  . TRP A 1 213 ? 84.720  77.603  94.332  1.00 104.65 ? 213 TRP A CD1  1 
ATOM   1552 C  CD2  . TRP A 1 213 ? 83.202  78.961  95.250  1.00 104.65 ? 213 TRP A CD2  1 
ATOM   1553 N  NE1  . TRP A 1 213 ? 84.377  77.079  95.553  1.00 104.65 ? 213 TRP A NE1  1 
ATOM   1554 C  CE2  . TRP A 1 213 ? 83.446  77.899  96.136  1.00 104.65 ? 213 TRP A CE2  1 
ATOM   1555 C  CE3  . TRP A 1 213 ? 82.281  79.944  95.616  1.00 104.65 ? 213 TRP A CE3  1 
ATOM   1556 C  CZ2  . TRP A 1 213 ? 82.802  77.788  97.357  1.00 104.65 ? 213 TRP A CZ2  1 
ATOM   1557 C  CZ3  . TRP A 1 213 ? 81.648  79.832  96.835  1.00 104.65 ? 213 TRP A CZ3  1 
ATOM   1558 C  CH2  . TRP A 1 213 ? 81.911  78.766  97.691  1.00 104.65 ? 213 TRP A CH2  1 
ATOM   1559 N  N    . ASP A 1 214 ? 83.090  80.136  89.637  1.00 112.99 ? 214 ASP A N    1 
ATOM   1560 C  CA   . ASP A 1 214 ? 82.944  81.048  88.514  1.00 112.99 ? 214 ASP A CA   1 
ATOM   1561 C  C    . ASP A 1 214 ? 81.542  81.039  87.918  1.00 112.99 ? 214 ASP A C    1 
ATOM   1562 O  O    . ASP A 1 214 ? 81.259  81.846  87.028  1.00 112.99 ? 214 ASP A O    1 
ATOM   1563 C  CB   . ASP A 1 214 ? 83.960  80.711  87.417  1.00 112.99 ? 214 ASP A CB   1 
ATOM   1564 C  CG   . ASP A 1 214 ? 85.340  81.259  87.715  1.00 112.99 ? 214 ASP A CG   1 
ATOM   1565 O  OD1  . ASP A 1 214 ? 85.467  82.056  88.666  1.00 112.99 ? 214 ASP A OD1  1 
ATOM   1566 O  OD2  . ASP A 1 214 ? 86.293  80.900  86.993  1.00 112.99 ? 214 ASP A OD2  1 
ATOM   1567 N  N    . TYR A 1 215 ? 80.661  80.158  88.386  1.00 124.29 ? 215 TYR A N    1 
ATOM   1568 C  CA   . TYR A 1 215 ? 79.312  80.063  87.841  1.00 124.29 ? 215 TYR A CA   1 
ATOM   1569 C  C    . TYR A 1 215 ? 78.473  81.194  88.410  1.00 124.29 ? 215 TYR A C    1 
ATOM   1570 O  O    . TYR A 1 215 ? 78.140  81.193  89.599  1.00 124.29 ? 215 TYR A O    1 
ATOM   1571 C  CB   . TYR A 1 215 ? 78.688  78.709  88.167  1.00 124.29 ? 215 TYR A CB   1 
ATOM   1572 C  CG   . TYR A 1 215 ? 77.194  78.666  87.941  1.00 124.29 ? 215 TYR A CG   1 
ATOM   1573 C  CD1  . TYR A 1 215 ? 76.666  78.643  86.656  1.00 124.29 ? 215 TYR A CD1  1 
ATOM   1574 C  CD2  . TYR A 1 215 ? 76.307  78.650  89.012  1.00 124.29 ? 215 TYR A CD2  1 
ATOM   1575 C  CE1  . TYR A 1 215 ? 75.301  78.605  86.442  1.00 124.29 ? 215 TYR A CE1  1 
ATOM   1576 C  CE2  . TYR A 1 215 ? 74.939  78.615  88.807  1.00 124.29 ? 215 TYR A CE2  1 
ATOM   1577 C  CZ   . TYR A 1 215 ? 74.445  78.591  87.520  1.00 124.29 ? 215 TYR A CZ   1 
ATOM   1578 O  OH   . TYR A 1 215 ? 73.087  78.554  87.313  1.00 124.29 ? 215 TYR A OH   1 
ATOM   1579 N  N    . THR A 1 216 ? 78.125  82.160  87.567  1.00 130.51 ? 216 THR A N    1 
ATOM   1580 C  CA   . THR A 1 216 ? 77.314  83.272  88.026  1.00 130.51 ? 216 THR A CA   1 
ATOM   1581 C  C    . THR A 1 216 ? 75.869  82.832  88.231  1.00 130.51 ? 216 THR A C    1 
ATOM   1582 O  O    . THR A 1 216 ? 75.422  81.801  87.718  1.00 130.51 ? 216 THR A O    1 
ATOM   1583 C  CB   . THR A 1 216 ? 77.369  84.432  87.033  1.00 130.51 ? 216 THR A CB   1 
ATOM   1584 O  OG1  . THR A 1 216 ? 76.701  85.569  87.590  1.00 130.51 ? 216 THR A OG1  1 
ATOM   1585 C  CG2  . THR A 1 216 ? 76.699  84.050  85.727  1.00 130.51 ? 216 THR A CG2  1 
ATOM   1586 N  N    . ILE A 1 217 ? 75.139  83.617  89.014  1.00 135.36 ? 217 ILE A N    1 
ATOM   1587 C  CA   . ILE A 1 217 ? 73.717  83.371  89.216  1.00 135.36 ? 217 ILE A CA   1 
ATOM   1588 C  C    . ILE A 1 217 ? 72.938  84.076  88.111  1.00 135.36 ? 217 ILE A C    1 
ATOM   1589 O  O    . ILE A 1 217 ? 73.190  85.256  87.827  1.00 135.36 ? 217 ILE A O    1 
ATOM   1590 C  CB   . ILE A 1 217 ? 73.253  83.827  90.609  1.00 135.36 ? 217 ILE A CB   1 
ATOM   1591 C  CG1  . ILE A 1 217 ? 73.751  85.239  90.921  1.00 135.36 ? 217 ILE A CG1  1 
ATOM   1592 C  CG2  . ILE A 1 217 ? 73.738  82.852  91.667  1.00 135.36 ? 217 ILE A CG2  1 
ATOM   1593 C  CD1  . ILE A 1 217 ? 73.014  85.893  92.065  1.00 135.36 ? 217 ILE A CD1  1 
ATOM   1594 N  N    . PRO A 1 218 ? 72.007  83.395  87.443  1.00 138.67 ? 218 PRO A N    1 
ATOM   1595 C  CA   . PRO A 1 218 ? 71.213  84.072  86.407  1.00 138.67 ? 218 PRO A CA   1 
ATOM   1596 C  C    . PRO A 1 218 ? 70.222  85.075  86.966  1.00 138.67 ? 218 PRO A C    1 
ATOM   1597 O  O    . PRO A 1 218 ? 69.656  85.857  86.192  1.00 138.67 ? 218 PRO A O    1 
ATOM   1598 C  CB   . PRO A 1 218 ? 70.498  82.914  85.701  1.00 138.67 ? 218 PRO A CB   1 
ATOM   1599 C  CG   . PRO A 1 218 ? 70.406  81.850  86.743  1.00 138.67 ? 218 PRO A CG   1 
ATOM   1600 C  CD   . PRO A 1 218 ? 71.649  81.972  87.576  1.00 138.67 ? 218 PRO A CD   1 
ATOM   1601 N  N    . ILE A 1 219 ? 69.988  85.074  88.279  1.00 143.78 ? 219 ILE A N    1 
ATOM   1602 C  CA   . ILE A 1 219 ? 69.018  85.991  88.869  1.00 143.78 ? 219 ILE A CA   1 
ATOM   1603 C  C    . ILE A 1 219 ? 69.521  87.429  88.802  1.00 143.78 ? 219 ILE A C    1 
ATOM   1604 O  O    . ILE A 1 219 ? 68.790  88.340  88.397  1.00 143.78 ? 219 ILE A O    1 
ATOM   1605 C  CB   . ILE A 1 219 ? 68.703  85.570  90.316  1.00 143.78 ? 219 ILE A CB   1 
ATOM   1606 C  CG1  . ILE A 1 219 ? 68.273  84.103  90.365  1.00 143.78 ? 219 ILE A CG1  1 
ATOM   1607 C  CG2  . ILE A 1 219 ? 67.629  86.467  90.909  1.00 143.78 ? 219 ILE A CG2  1 
ATOM   1608 C  CD1  . ILE A 1 219 ? 68.109  83.560  91.767  1.00 143.78 ? 219 ILE A CD1  1 
ATOM   1609 N  N    . LEU A 1 220 ? 70.780  87.657  89.193  1.00 139.80 ? 220 LEU A N    1 
ATOM   1610 C  CA   . LEU A 1 220 ? 71.317  89.010  89.277  1.00 139.80 ? 220 LEU A CA   1 
ATOM   1611 C  C    . LEU A 1 220 ? 72.721  89.140  88.699  1.00 139.80 ? 220 LEU A C    1 
ATOM   1612 O  O    . LEU A 1 220 ? 73.363  90.177  88.912  1.00 139.80 ? 220 LEU A O    1 
ATOM   1613 C  CB   . LEU A 1 220 ? 71.316  89.502  90.731  1.00 139.80 ? 220 LEU A CB   1 
ATOM   1614 C  CG   . LEU A 1 220 ? 69.955  89.742  91.390  1.00 139.80 ? 220 LEU A CG   1 
ATOM   1615 C  CD1  . LEU A 1 220 ? 70.120  90.095  92.861  1.00 139.80 ? 220 LEU A CD1  1 
ATOM   1616 C  CD2  . LEU A 1 220 ? 69.185  90.830  90.656  1.00 139.80 ? 220 LEU A CD2  1 
ATOM   1617 N  N    . GLU A 1 221 ? 73.209  88.123  87.981  1.00 137.61 ? 221 GLU A N    1 
ATOM   1618 C  CA   . GLU A 1 221 ? 74.513  88.154  87.308  1.00 137.61 ? 221 GLU A CA   1 
ATOM   1619 C  C    . GLU A 1 221 ? 75.647  88.450  88.291  1.00 137.61 ? 221 GLU A C    1 
ATOM   1620 O  O    . GLU A 1 221 ? 76.469  89.344  88.084  1.00 137.61 ? 221 GLU A O    1 
ATOM   1621 C  CB   . GLU A 1 221 ? 74.511  89.156  86.150  1.00 137.61 ? 221 GLU A CB   1 
ATOM   1622 C  CG   . GLU A 1 221 ? 73.364  88.957  85.174  1.00 137.61 ? 221 GLU A CG   1 
ATOM   1623 C  CD   . GLU A 1 221 ? 73.340  87.563  84.580  1.00 137.61 ? 221 GLU A CD   1 
ATOM   1624 O  OE1  . GLU A 1 221 ? 74.392  87.112  84.079  1.00 137.61 ? 221 GLU A OE1  1 
ATOM   1625 O  OE2  . GLU A 1 221 ? 72.273  86.918  84.616  1.00 137.61 ? 221 GLU A OE2  1 
ATOM   1626 N  N    . ILE A 1 222 ? 75.675  87.688  89.382  1.00 129.65 ? 222 ILE A N    1 
ATOM   1627 C  CA   . ILE A 1 222 ? 76.677  87.833  90.430  1.00 129.65 ? 222 ILE A CA   1 
ATOM   1628 C  C    . ILE A 1 222 ? 77.560  86.596  90.420  1.00 129.65 ? 222 ILE A C    1 
ATOM   1629 O  O    . ILE A 1 222 ? 77.064  85.468  90.321  1.00 129.65 ? 222 ILE A O    1 
ATOM   1630 C  CB   . ILE A 1 222 ? 76.021  88.045  91.804  1.00 129.65 ? 222 ILE A CB   1 
ATOM   1631 C  CG1  . ILE A 1 222 ? 74.992  89.174  91.722  1.00 129.65 ? 222 ILE A CG1  1 
ATOM   1632 C  CG2  . ILE A 1 222 ? 77.064  88.367  92.846  1.00 129.65 ? 222 ILE A CG2  1 
ATOM   1633 C  CD1  . ILE A 1 222 ? 74.374  89.543  93.052  1.00 129.65 ? 222 ILE A CD1  1 
ATOM   1634 N  N    . LYS A 1 223 ? 78.871  86.810  90.552  1.00 117.84 ? 223 LYS A N    1 
ATOM   1635 C  CA   . LYS A 1 223 ? 79.886  85.797  90.280  1.00 117.84 ? 223 LYS A CA   1 
ATOM   1636 C  C    . LYS A 1 223 ? 79.858  84.626  91.260  1.00 117.84 ? 223 LYS A C    1 
ATOM   1637 O  O    . LYS A 1 223 ? 80.533  83.622  91.010  1.00 117.84 ? 223 LYS A O    1 
ATOM   1638 C  CB   . LYS A 1 223 ? 81.261  86.472  90.289  1.00 117.84 ? 223 LYS A CB   1 
ATOM   1639 C  CG   . LYS A 1 223 ? 82.373  85.729  89.575  1.00 117.84 ? 223 LYS A CG   1 
ATOM   1640 C  CD   . LYS A 1 223 ? 82.174  85.755  88.073  1.00 117.84 ? 223 LYS A CD   1 
ATOM   1641 C  CE   . LYS A 1 223 ? 83.474  85.466  87.349  1.00 117.84 ? 223 LYS A CE   1 
ATOM   1642 N  NZ   . LYS A 1 223 ? 84.010  84.126  87.689  1.00 117.84 ? 223 LYS A NZ   1 
ATOM   1643 N  N    . LEU A 1 224 ? 79.110  84.740  92.361  1.00 111.63 ? 224 LEU A N    1 
ATOM   1644 C  CA   . LEU A 1 224 ? 78.904  83.797  93.459  1.00 111.63 ? 224 LEU A CA   1 
ATOM   1645 C  C    . LEU A 1 224 ? 80.110  83.751  94.400  1.00 111.63 ? 224 LEU A C    1 
ATOM   1646 O  O    . LEU A 1 224 ? 79.994  83.212  95.499  1.00 111.63 ? 224 LEU A O    1 
ATOM   1647 C  CB   . LEU A 1 224 ? 78.554  82.368  92.983  1.00 111.63 ? 224 LEU A CB   1 
ATOM   1648 C  CG   . LEU A 1 224 ? 78.209  81.243  93.966  1.00 111.63 ? 224 LEU A CG   1 
ATOM   1649 C  CD1  . LEU A 1 224 ? 76.952  81.586  94.748  1.00 111.63 ? 224 LEU A CD1  1 
ATOM   1650 C  CD2  . LEU A 1 224 ? 78.058  79.914  93.253  1.00 111.63 ? 224 LEU A CD2  1 
ATOM   1651 N  N    . LYS A 1 225 ? 81.236  84.365  94.055  1.00 104.00 ? 225 LYS A N    1 
ATOM   1652 C  CA   . LYS A 1 225 ? 82.267  84.613  95.050  1.00 104.00 ? 225 LYS A CA   1 
ATOM   1653 C  C    . LYS A 1 225 ? 81.935  85.816  95.904  1.00 104.00 ? 225 LYS A C    1 
ATOM   1654 O  O    . LYS A 1 225 ? 82.689  86.138  96.828  1.00 104.00 ? 225 LYS A O    1 
ATOM   1655 C  CB   . LYS A 1 225 ? 83.622  84.826  94.380  1.00 104.00 ? 225 LYS A CB   1 
ATOM   1656 C  CG   . LYS A 1 225 ? 84.082  83.665  93.537  1.00 104.00 ? 225 LYS A CG   1 
ATOM   1657 C  CD   . LYS A 1 225 ? 85.435  83.946  92.936  1.00 104.00 ? 225 LYS A CD   1 
ATOM   1658 C  CE   . LYS A 1 225 ? 85.866  82.814  92.039  1.00 104.00 ? 225 LYS A CE   1 
ATOM   1659 N  NZ   . LYS A 1 225 ? 85.041  82.784  90.809  1.00 104.00 ? 225 LYS A NZ   1 
ATOM   1660 N  N    . ILE A 1 226 ? 80.829  86.486  95.609  1.00 102.21 ? 226 ILE A N    1 
ATOM   1661 C  CA   . ILE A 1 226 ? 80.445  87.732  96.246  1.00 102.21 ? 226 ILE A CA   1 
ATOM   1662 C  C    . ILE A 1 226 ? 79.458  87.445  97.369  1.00 102.21 ? 226 ILE A C    1 
ATOM   1663 O  O    . ILE A 1 226 ? 79.439  88.148  98.383  1.00 102.21 ? 226 ILE A O    1 
ATOM   1664 C  CB   . ILE A 1 226 ? 79.856  88.700  95.201  1.00 102.21 ? 226 ILE A CB   1 
ATOM   1665 C  CG1  . ILE A 1 226 ? 80.767  88.762  93.975  1.00 102.21 ? 226 ILE A CG1  1 
ATOM   1666 C  CG2  . ILE A 1 226 ? 79.682  90.088  95.763  1.00 102.21 ? 226 ILE A CG2  1 
ATOM   1667 C  CD1  . ILE A 1 226 ? 82.141  89.327  94.266  1.00 102.21 ? 226 ILE A CD1  1 
ATOM   1668 N  N    . LEU A 1 227 ? 78.634  86.413  97.199  1.00 98.00  ? 227 LEU A N    1 
ATOM   1669 C  CA   . LEU A 1 227 ? 77.635  86.096  98.218  1.00 98.00  ? 227 LEU A CA   1 
ATOM   1670 C  C    . LEU A 1 227 ? 78.242  85.677  99.558  1.00 98.00  ? 227 LEU A C    1 
ATOM   1671 O  O    . LEU A 1 227 ? 77.842  86.251  100.587 1.00 98.00  ? 227 LEU A O    1 
ATOM   1672 C  CB   . LEU A 1 227 ? 76.660  85.044  97.677  1.00 98.00  ? 227 LEU A CB   1 
ATOM   1673 C  CG   . LEU A 1 227 ? 75.557  84.620  98.643  1.00 98.00  ? 227 LEU A CG   1 
ATOM   1674 C  CD1  . LEU A 1 227 ? 74.705  85.813  99.037  1.00 98.00  ? 227 LEU A CD1  1 
ATOM   1675 C  CD2  . LEU A 1 227 ? 74.701  83.536  98.019  1.00 98.00  ? 227 LEU A CD2  1 
ATOM   1676 N  N    . PRO A 1 228 ? 79.180  84.720  99.639  1.00 91.51  ? 228 PRO A N    1 
ATOM   1677 C  CA   . PRO A 1 228 ? 79.745  84.405  100.958 1.00 91.51  ? 228 PRO A CA   1 
ATOM   1678 C  C    . PRO A 1 228 ? 80.567  85.535  101.540 1.00 91.51  ? 228 PRO A C    1 
ATOM   1679 O  O    . PRO A 1 228 ? 80.541  85.735  102.760 1.00 91.51  ? 228 PRO A O    1 
ATOM   1680 C  CB   . PRO A 1 228 ? 80.605  83.162  100.695 1.00 91.51  ? 228 PRO A CB   1 
ATOM   1681 C  CG   . PRO A 1 228 ? 80.152  82.644  99.394  1.00 91.51  ? 228 PRO A CG   1 
ATOM   1682 C  CD   . PRO A 1 228 ? 79.777  83.849  98.613  1.00 91.51  ? 228 PRO A CD   1 
ATOM   1683 N  N    . VAL A 1 229 ? 81.280  86.298  100.709 1.00 89.77  ? 229 VAL A N    1 
ATOM   1684 C  CA   . VAL A 1 229 ? 82.081  87.380  101.260 1.00 89.77  ? 229 VAL A CA   1 
ATOM   1685 C  C    . VAL A 1 229 ? 81.195  88.520  101.754 1.00 89.77  ? 229 VAL A C    1 
ATOM   1686 O  O    . VAL A 1 229 ? 81.531  89.182  102.739 1.00 89.77  ? 229 VAL A O    1 
ATOM   1687 C  CB   . VAL A 1 229 ? 83.145  87.851  100.250 1.00 89.77  ? 229 VAL A CB   1 
ATOM   1688 C  CG1  . VAL A 1 229 ? 82.541  88.668  99.140  1.00 89.77  ? 229 VAL A CG1  1 
ATOM   1689 C  CG2  . VAL A 1 229 ? 84.210  88.650  100.959 1.00 89.77  ? 229 VAL A CG2  1 
ATOM   1690 N  N    . LEU A 1 230 ? 80.031  88.746  101.138 1.00 92.56  ? 230 LEU A N    1 
ATOM   1691 C  CA   . LEU A 1 230 ? 79.115  89.740  101.690 1.00 92.56  ? 230 LEU A CA   1 
ATOM   1692 C  C    . LEU A 1 230 ? 78.365  89.239  102.912 1.00 92.56  ? 230 LEU A C    1 
ATOM   1693 O  O    . LEU A 1 230 ? 78.049  90.042  103.795 1.00 92.56  ? 230 LEU A O    1 
ATOM   1694 C  CB   . LEU A 1 230 ? 78.134  90.237  100.629 1.00 92.56  ? 230 LEU A CB   1 
ATOM   1695 C  CG   . LEU A 1 230 ? 78.568  91.448  99.796  1.00 92.56  ? 230 LEU A CG   1 
ATOM   1696 C  CD1  . LEU A 1 230 ? 78.668  92.645  100.722 1.00 92.56  ? 230 LEU A CD1  1 
ATOM   1697 C  CD2  . LEU A 1 230 ? 79.899  91.266  99.113  1.00 92.56  ? 230 LEU A CD2  1 
ATOM   1698 N  N    . GLY A 1 231 ? 78.078  87.940  103.000 1.00 89.25  ? 231 GLY A N    1 
ATOM   1699 C  CA   . GLY A 1 231 ? 77.578  87.415  104.260 1.00 89.25  ? 231 GLY A CA   1 
ATOM   1700 C  C    . GLY A 1 231 ? 78.578  87.600  105.385 1.00 89.25  ? 231 GLY A C    1 
ATOM   1701 O  O    . GLY A 1 231 ? 78.225  88.042  106.487 1.00 89.25  ? 231 GLY A O    1 
ATOM   1702 N  N    . PHE A 1 232 ? 79.848  87.299  105.106 1.00 84.55  ? 232 PHE A N    1 
ATOM   1703 C  CA   . PHE A 1 232 ? 80.910  87.520  106.078 1.00 84.55  ? 232 PHE A CA   1 
ATOM   1704 C  C    . PHE A 1 232 ? 81.028  88.992  106.431 1.00 84.55  ? 232 PHE A C    1 
ATOM   1705 O  O    . PHE A 1 232 ? 81.204  89.339  107.600 1.00 84.55  ? 232 PHE A O    1 
ATOM   1706 C  CB   . PHE A 1 232 ? 82.232  86.989  105.524 1.00 84.55  ? 232 PHE A CB   1 
ATOM   1707 C  CG   . PHE A 1 232 ? 83.403  87.199  106.434 1.00 84.55  ? 232 PHE A CG   1 
ATOM   1708 C  CD1  . PHE A 1 232 ? 83.644  86.331  107.483 1.00 84.55  ? 232 PHE A CD1  1 
ATOM   1709 C  CD2  . PHE A 1 232 ? 84.272  88.253  106.234 1.00 84.55  ? 232 PHE A CD2  1 
ATOM   1710 C  CE1  . PHE A 1 232 ? 84.723  86.518  108.318 1.00 84.55  ? 232 PHE A CE1  1 
ATOM   1711 C  CE2  . PHE A 1 232 ? 85.351  88.442  107.067 1.00 84.55  ? 232 PHE A CE2  1 
ATOM   1712 C  CZ   . PHE A 1 232 ? 85.576  87.574  108.108 1.00 84.55  ? 232 PHE A CZ   1 
ATOM   1713 N  N    . LEU A 1 233 ? 80.923  89.872  105.434 1.00 84.50  ? 233 LEU A N    1 
ATOM   1714 C  CA   . LEU A 1 233 ? 81.020  91.303  105.688 1.00 84.50  ? 233 LEU A CA   1 
ATOM   1715 C  C    . LEU A 1 233 ? 79.871  91.793  106.562 1.00 84.50  ? 233 LEU A C    1 
ATOM   1716 O  O    . LEU A 1 233 ? 80.079  92.609  107.465 1.00 84.50  ? 233 LEU A O    1 
ATOM   1717 C  CB   . LEU A 1 233 ? 81.050  92.057  104.362 1.00 84.50  ? 233 LEU A CB   1 
ATOM   1718 C  CG   . LEU A 1 233 ? 81.700  93.436  104.401 1.00 84.50  ? 233 LEU A CG   1 
ATOM   1719 C  CD1  . LEU A 1 233 ? 83.142  93.307  104.847 1.00 84.50  ? 233 LEU A CD1  1 
ATOM   1720 C  CD2  . LEU A 1 233 ? 81.615  94.105  103.045 1.00 84.50  ? 233 LEU A CD2  1 
ATOM   1721 N  N    . GLY A 1 234 ? 78.654  91.306  106.316 1.00 86.69  ? 234 GLY A N    1 
ATOM   1722 C  CA   . GLY A 1 234 ? 77.532  91.686  107.160 1.00 86.69  ? 234 GLY A CA   1 
ATOM   1723 C  C    . GLY A 1 234 ? 77.705  91.225  108.594 1.00 86.69  ? 234 GLY A C    1 
ATOM   1724 O  O    . GLY A 1 234 ? 77.454  91.982  109.540 1.00 86.69  ? 234 GLY A O    1 
ATOM   1725 N  N    . GLY A 1 235 ? 78.148  89.979  108.776 1.00 83.49  ? 235 GLY A N    1 
ATOM   1726 C  CA   . GLY A 1 235 ? 78.453  89.512  110.117 1.00 83.49  ? 235 GLY A CA   1 
ATOM   1727 C  C    . GLY A 1 235 ? 79.554  90.318  110.779 1.00 83.49  ? 235 GLY A C    1 
ATOM   1728 O  O    . GLY A 1 235 ? 79.522  90.544  111.993 1.00 83.49  ? 235 GLY A O    1 
ATOM   1729 N  N    . VAL A 1 236 ? 80.540  90.754  109.994 1.00 80.14  ? 236 VAL A N    1 
ATOM   1730 C  CA   . VAL A 1 236 ? 81.560  91.670  110.491 1.00 80.14  ? 236 VAL A CA   1 
ATOM   1731 C  C    . VAL A 1 236 ? 80.925  92.962  110.970 1.00 80.14  ? 236 VAL A C    1 
ATOM   1732 O  O    . VAL A 1 236 ? 81.325  93.517  111.995 1.00 80.14  ? 236 VAL A O    1 
ATOM   1733 C  CB   . VAL A 1 236 ? 82.618  91.925  109.406 1.00 80.14  ? 236 VAL A CB   1 
ATOM   1734 C  CG1  . VAL A 1 236 ? 83.475  93.116  109.759 1.00 80.14  ? 236 VAL A CG1  1 
ATOM   1735 C  CG2  . VAL A 1 236 ? 83.493  90.709  109.260 1.00 80.14  ? 236 VAL A CG2  1 
ATOM   1736 N  N    . ILE A 1 237 ? 79.926  93.463  110.242 1.00 84.11  ? 237 ILE A N    1 
ATOM   1737 C  CA   . ILE A 1 237 ? 79.249  94.687  110.670 1.00 84.11  ? 237 ILE A CA   1 
ATOM   1738 C  C    . ILE A 1 237 ? 78.566  94.480  112.018 1.00 84.11  ? 237 ILE A C    1 
ATOM   1739 O  O    . ILE A 1 237 ? 78.696  95.309  112.928 1.00 84.11  ? 237 ILE A O    1 
ATOM   1740 C  CB   . ILE A 1 237 ? 78.262  95.175  109.596 1.00 84.11  ? 237 ILE A CB   1 
ATOM   1741 C  CG1  . ILE A 1 237 ? 78.995  95.448  108.289 1.00 84.11  ? 237 ILE A CG1  1 
ATOM   1742 C  CG2  . ILE A 1 237 ? 77.544  96.427  110.059 1.00 84.11  ? 237 ILE A CG2  1 
ATOM   1743 C  CD1  . ILE A 1 237 ? 80.053  96.525  108.405 1.00 84.11  ? 237 ILE A CD1  1 
ATOM   1744 N  N    . PHE A 1 238 ? 77.858  93.355  112.180 1.00 87.03  ? 238 PHE A N    1 
ATOM   1745 C  CA   . PHE A 1 238 ? 77.237  93.066  113.478 1.00 87.03  ? 238 PHE A CA   1 
ATOM   1746 C  C    . PHE A 1 238 ? 78.273  93.003  114.595 1.00 87.03  ? 238 PHE A C    1 
ATOM   1747 O  O    . PHE A 1 238 ? 78.137  93.677  115.626 1.00 87.03  ? 238 PHE A O    1 
ATOM   1748 C  CB   . PHE A 1 238 ? 76.435  91.763  113.454 1.00 87.03  ? 238 PHE A CB   1 
ATOM   1749 C  CG   . PHE A 1 238 ? 75.208  91.802  112.592 1.00 87.03  ? 238 PHE A CG   1 
ATOM   1750 C  CD1  . PHE A 1 238 ? 74.044  92.385  113.064 1.00 87.03  ? 238 PHE A CD1  1 
ATOM   1751 C  CD2  . PHE A 1 238 ? 75.187  91.190  111.353 1.00 87.03  ? 238 PHE A CD2  1 
ATOM   1752 C  CE1  . PHE A 1 238 ? 72.899  92.409  112.288 1.00 87.03  ? 238 PHE A CE1  1 
ATOM   1753 C  CE2  . PHE A 1 238 ? 74.047  91.212  110.570 1.00 87.03  ? 238 PHE A CE2  1 
ATOM   1754 C  CZ   . PHE A 1 238 ? 72.901  91.817  111.041 1.00 87.03  ? 238 PHE A CZ   1 
ATOM   1755 N  N    . SER A 1 239 ? 79.325  92.206  114.401 1.00 84.94  ? 239 SER A N    1 
ATOM   1756 C  CA   . SER A 1 239 ? 80.297  91.995  115.468 1.00 84.94  ? 239 SER A CA   1 
ATOM   1757 C  C    . SER A 1 239 ? 81.084  93.263  115.770 1.00 84.94  ? 239 SER A C    1 
ATOM   1758 O  O    . SER A 1 239 ? 81.396  93.543  116.932 1.00 84.94  ? 239 SER A O    1 
ATOM   1759 C  CB   . SER A 1 239 ? 81.239  90.850  115.103 1.00 84.94  ? 239 SER A CB   1 
ATOM   1760 O  OG   . SER A 1 239 ? 80.619  89.593  115.308 1.00 84.94  ? 239 SER A OG   1 
ATOM   1761 N  N    . CYS A 1 240 ? 81.406  94.053  114.746 1.00 90.02  ? 240 CYS A N    1 
ATOM   1762 C  CA   . CYS A 1 240 ? 82.174  95.266  114.972 1.00 90.02  ? 240 CYS A CA   1 
ATOM   1763 C  C    . CYS A 1 240 ? 81.326  96.347  115.618 1.00 90.02  ? 240 CYS A C    1 
ATOM   1764 O  O    . CYS A 1 240 ? 81.849  97.133  116.413 1.00 90.02  ? 240 CYS A O    1 
ATOM   1765 C  CB   . CYS A 1 240 ? 82.771  95.773  113.661 1.00 90.02  ? 240 CYS A CB   1 
ATOM   1766 S  SG   . CYS A 1 240 ? 81.632  96.724  112.637 1.00 90.02  ? 240 CYS A SG   1 
ATOM   1767 N  N    . SER A 1 241 ? 80.029  96.414  115.310 1.00 86.90  ? 241 SER A N    1 
ATOM   1768 C  CA   . SER A 1 241 ? 79.164  97.323  116.056 1.00 86.90  ? 241 SER A CA   1 
ATOM   1769 C  C    . SER A 1 241 ? 79.063  96.903  117.514 1.00 86.90  ? 241 SER A C    1 
ATOM   1770 O  O    . SER A 1 241 ? 79.131  97.746  118.422 1.00 86.90  ? 241 SER A O    1 
ATOM   1771 C  CB   . SER A 1 241 ? 77.780  97.385  115.417 1.00 86.90  ? 241 SER A CB   1 
ATOM   1772 O  OG   . SER A 1 241 ? 77.031  98.468  115.941 1.00 86.90  ? 241 SER A OG   1 
ATOM   1773 N  N    . ASN A 1 242 ? 78.925  95.595  117.753 1.00 84.09  ? 242 ASN A N    1 
ATOM   1774 C  CA   . ASN A 1 242 ? 78.851  95.083  119.116 1.00 84.09  ? 242 ASN A CA   1 
ATOM   1775 C  C    . ASN A 1 242 ? 80.126  95.400  119.888 1.00 84.09  ? 242 ASN A C    1 
ATOM   1776 O  O    . ASN A 1 242 ? 80.062  95.757  121.069 1.00 84.09  ? 242 ASN A O    1 
ATOM   1777 C  CB   . ASN A 1 242 ? 78.592  93.575  119.071 1.00 84.09  ? 242 ASN A CB   1 
ATOM   1778 C  CG   . ASN A 1 242 ? 78.280  92.977  120.432 1.00 84.09  ? 242 ASN A CG   1 
ATOM   1779 O  OD1  . ASN A 1 242 ? 78.273  93.662  121.451 1.00 84.09  ? 242 ASN A OD1  1 
ATOM   1780 N  ND2  . ASN A 1 242 ? 78.011  91.678  120.446 1.00 84.09  ? 242 ASN A ND2  1 
ATOM   1781 N  N    . TYR A 1 243 ? 81.284  95.289  119.239 1.00 84.16  ? 243 TYR A N    1 
ATOM   1782 C  CA   . TYR A 1 243 ? 82.541  95.660  119.880 1.00 84.16  ? 243 TYR A CA   1 
ATOM   1783 C  C    . TYR A 1 243 ? 82.642  97.166  120.112 1.00 84.16  ? 243 TYR A C    1 
ATOM   1784 O  O    . TYR A 1 243 ? 82.945  97.607  121.223 1.00 84.16  ? 243 TYR A O    1 
ATOM   1785 C  CB   . TYR A 1 243 ? 83.722  95.178  119.036 1.00 84.16  ? 243 TYR A CB   1 
ATOM   1786 C  CG   . TYR A 1 243 ? 83.909  93.684  119.048 1.00 84.16  ? 243 TYR A CG   1 
ATOM   1787 C  CD1  . TYR A 1 243 ? 83.555  92.932  120.155 1.00 84.16  ? 243 TYR A CD1  1 
ATOM   1788 C  CD2  . TYR A 1 243 ? 84.437  93.024  117.950 1.00 84.16  ? 243 TYR A CD2  1 
ATOM   1789 C  CE1  . TYR A 1 243 ? 83.724  91.571  120.170 1.00 84.16  ? 243 TYR A CE1  1 
ATOM   1790 C  CE2  . TYR A 1 243 ? 84.607  91.663  117.957 1.00 84.16  ? 243 TYR A CE2  1 
ATOM   1791 C  CZ   . TYR A 1 243 ? 84.248  90.944  119.070 1.00 84.16  ? 243 TYR A CZ   1 
ATOM   1792 O  OH   . TYR A 1 243 ? 84.414  89.583  119.088 1.00 84.16  ? 243 TYR A OH   1 
ATOM   1793 N  N    . PHE A 1 244 ? 82.378  97.969  119.081 1.00 82.77  ? 244 PHE A N    1 
ATOM   1794 C  CA   . PHE A 1 244 ? 82.589  99.406  119.182 1.00 82.77  ? 244 PHE A CA   1 
ATOM   1795 C  C    . PHE A 1 244 ? 81.652  100.080 120.166 1.00 82.77  ? 244 PHE A C    1 
ATOM   1796 O  O    . PHE A 1 244 ? 82.012  101.132 120.702 1.00 82.77  ? 244 PHE A O    1 
ATOM   1797 C  CB   . PHE A 1 244 ? 82.453  100.058 117.810 1.00 82.77  ? 244 PHE A CB   1 
ATOM   1798 C  CG   . PHE A 1 244 ? 83.613  99.799  116.898 1.00 82.77  ? 244 PHE A CG   1 
ATOM   1799 C  CD1  . PHE A 1 244 ? 84.816  99.347  117.404 1.00 82.77  ? 244 PHE A CD1  1 
ATOM   1800 C  CD2  . PHE A 1 244 ? 83.503  100.013 115.539 1.00 82.77  ? 244 PHE A CD2  1 
ATOM   1801 C  CE1  . PHE A 1 244 ? 85.883  99.120  116.572 1.00 82.77  ? 244 PHE A CE1  1 
ATOM   1802 C  CE2  . PHE A 1 244 ? 84.568  99.780  114.703 1.00 82.77  ? 244 PHE A CE2  1 
ATOM   1803 C  CZ   . PHE A 1 244 ? 85.759  99.332  115.218 1.00 82.77  ? 244 PHE A CZ   1 
ATOM   1804 N  N    . HIS A 1 245 ? 80.479  99.497  120.432 1.00 87.50  ? 245 HIS A N    1 
ATOM   1805 C  CA   . HIS A 1 245 ? 79.589  100.096 121.421 1.00 87.50  ? 245 HIS A CA   1 
ATOM   1806 C  C    . HIS A 1 245 ? 80.255  100.173 122.788 1.00 87.50  ? 245 HIS A C    1 
ATOM   1807 O  O    . HIS A 1 245 ? 80.202  101.210 123.457 1.00 87.50  ? 245 HIS A O    1 
ATOM   1808 C  CB   . HIS A 1 245 ? 78.285  99.309  121.510 1.00 87.50  ? 245 HIS A CB   1 
ATOM   1809 C  CG   . HIS A 1 245 ? 77.265  99.940  122.404 1.00 87.50  ? 245 HIS A CG   1 
ATOM   1810 N  ND1  . HIS A 1 245 ? 77.238  99.730  123.765 1.00 87.50  ? 245 HIS A ND1  1 
ATOM   1811 C  CD2  . HIS A 1 245 ? 76.243  100.785 122.132 1.00 87.50  ? 245 HIS A CD2  1 
ATOM   1812 C  CE1  . HIS A 1 245 ? 76.240  100.414 124.293 1.00 87.50  ? 245 HIS A CE1  1 
ATOM   1813 N  NE2  . HIS A 1 245 ? 75.620  101.063 123.324 1.00 87.50  ? 245 HIS A NE2  1 
ATOM   1814 N  N    . VAL A 1 246 ? 80.931  99.101  123.201 1.00 85.15  ? 246 VAL A N    1 
ATOM   1815 C  CA   . VAL A 1 246 ? 81.632  99.114  124.479 1.00 85.15  ? 246 VAL A CA   1 
ATOM   1816 C  C    . VAL A 1 246 ? 83.047  99.682  124.350 1.00 85.15  ? 246 VAL A C    1 
ATOM   1817 O  O    . VAL A 1 246 ? 83.626  100.110 125.359 1.00 85.15  ? 246 VAL A O    1 
ATOM   1818 C  CB   . VAL A 1 246 ? 81.628  97.699  125.089 1.00 85.15  ? 246 VAL A CB   1 
ATOM   1819 C  CG1  . VAL A 1 246 ? 82.412  96.754  124.242 1.00 85.15  ? 246 VAL A CG1  1 
ATOM   1820 C  CG2  . VAL A 1 246 ? 82.112  97.684  126.537 1.00 85.15  ? 246 VAL A CG2  1 
ATOM   1821 N  N    . ILE A 1 247 ? 83.613  99.728  123.139 1.00 84.27  ? 247 ILE A N    1 
ATOM   1822 C  CA   . ILE A 1 247 ? 84.840  100.500 122.939 1.00 84.27  ? 247 ILE A CA   1 
ATOM   1823 C  C    . ILE A 1 247 ? 84.601  101.968 123.270 1.00 84.27  ? 247 ILE A C    1 
ATOM   1824 O  O    . ILE A 1 247 ? 85.400  102.606 123.968 1.00 84.27  ? 247 ILE A O    1 
ATOM   1825 C  CB   . ILE A 1 247 ? 85.374  100.340 121.503 1.00 84.27  ? 247 ILE A CB   1 
ATOM   1826 C  CG1  . ILE A 1 247 ? 85.788  98.903  121.218 1.00 84.27  ? 247 ILE A CG1  1 
ATOM   1827 C  CG2  . ILE A 1 247 ? 86.556  101.250 121.271 1.00 84.27  ? 247 ILE A CG2  1 
ATOM   1828 C  CD1  . ILE A 1 247 ? 86.923  98.431  122.078 1.00 84.27  ? 247 ILE A CD1  1 
ATOM   1829 N  N    . LEU A 1 248 ? 83.493  102.520 122.789 1.00 89.02  ? 248 LEU A N    1 
ATOM   1830 C  CA   . LEU A 1 248 ? 83.170  103.919 123.025 1.00 89.02  ? 248 LEU A CA   1 
ATOM   1831 C  C    . LEU A 1 248 ? 82.313  104.141 124.264 1.00 89.02  ? 248 LEU A C    1 
ATOM   1832 O  O    . LEU A 1 248 ? 82.021  105.294 124.594 1.00 89.02  ? 248 LEU A O    1 
ATOM   1833 C  CB   . LEU A 1 248 ? 82.460  104.515 121.805 1.00 89.02  ? 248 LEU A CB   1 
ATOM   1834 C  CG   . LEU A 1 248 ? 83.338  105.131 120.712 1.00 89.02  ? 248 LEU A CG   1 
ATOM   1835 C  CD1  . LEU A 1 248 ? 84.162  106.274 121.287 1.00 89.02  ? 248 LEU A CD1  1 
ATOM   1836 C  CD2  . LEU A 1 248 ? 84.231  104.107 120.028 1.00 89.02  ? 248 LEU A CD2  1 
ATOM   1837 N  N    . HIS A 1 249 ? 81.886  103.079 124.950 1.00 90.43  ? 249 HIS A N    1 
ATOM   1838 C  CA   . HIS A 1 249 ? 81.077  103.264 126.147 1.00 90.43  ? 249 HIS A CA   1 
ATOM   1839 C  C    . HIS A 1 249 ? 81.463  102.334 127.291 1.00 90.43  ? 249 HIS A C    1 
ATOM   1840 O  O    . HIS A 1 249 ? 80.618  102.066 128.156 1.00 90.43  ? 249 HIS A O    1 
ATOM   1841 C  CB   . HIS A 1 249 ? 79.597  103.093 125.810 1.00 90.43  ? 249 HIS A CB   1 
ATOM   1842 C  CG   . HIS A 1 249 ? 79.108  104.051 124.773 1.00 90.43  ? 249 HIS A CG   1 
ATOM   1843 N  ND1  . HIS A 1 249 ? 79.258  103.822 123.423 1.00 90.43  ? 249 HIS A ND1  1 
ATOM   1844 C  CD2  . HIS A 1 249 ? 78.491  105.250 124.885 1.00 90.43  ? 249 HIS A CD2  1 
ATOM   1845 C  CE1  . HIS A 1 249 ? 78.744  104.834 122.748 1.00 90.43  ? 249 HIS A CE1  1 
ATOM   1846 N  NE2  . HIS A 1 249 ? 78.272  105.715 123.612 1.00 90.43  ? 249 HIS A NE2  1 
ATOM   1847 N  N    . GLY A 1 250 ? 82.688  101.822 127.323 1.00 94.67  ? 250 GLY A N    1 
ATOM   1848 C  CA   . GLY A 1 250 ? 83.143  101.052 128.462 1.00 94.67  ? 250 GLY A CA   1 
ATOM   1849 C  C    . GLY A 1 250 ? 84.334  101.687 129.153 1.00 94.67  ? 250 GLY A C    1 
ATOM   1850 O  O    . GLY A 1 250 ? 85.440  101.697 128.609 1.00 94.67  ? 250 GLY A O    1 
ATOM   1851 N  N    . GLY A 1 251 ? 84.123  102.215 130.355 1.00 105.58 ? 251 GLY A N    1 
ATOM   1852 C  CA   . GLY A 1 251 ? 85.209  102.802 131.113 1.00 105.58 ? 251 GLY A CA   1 
ATOM   1853 C  C    . GLY A 1 251 ? 85.390  102.109 132.445 1.00 105.58 ? 251 GLY A C    1 
ATOM   1854 O  O    . GLY A 1 251 ? 84.538  102.230 133.332 1.00 105.58 ? 251 GLY A O    1 
ATOM   1855 N  N    . VAL A 1 252 ? 86.495  101.389 132.605 1.00 106.54 ? 252 VAL A N    1 
ATOM   1856 C  CA   . VAL A 1 252 ? 86.724  100.539 133.764 1.00 106.54 ? 252 VAL A CA   1 
ATOM   1857 C  C    . VAL A 1 252 ? 87.821  101.101 134.660 1.00 106.54 ? 252 VAL A C    1 
ATOM   1858 O  O    . VAL A 1 252 ? 87.605  101.313 135.852 1.00 106.54 ? 252 VAL A O    1 
ATOM   1859 C  CB   . VAL A 1 252 ? 87.050  99.094  133.329 1.00 106.54 ? 252 VAL A CB   1 
ATOM   1860 C  CG1  . VAL A 1 252 ? 87.330  98.232  134.545 1.00 106.54 ? 252 VAL A CG1  1 
ATOM   1861 C  CG2  . VAL A 1 252 ? 85.904  98.527  132.515 1.00 106.54 ? 252 VAL A CG2  1 
ATOM   1862 N  N    . GLY A 1 253 ? 89.004  101.345 134.100 1.00 111.09 ? 253 GLY A N    1 
ATOM   1863 C  CA   . GLY A 1 253 ? 90.114  101.821 134.907 1.00 111.09 ? 253 GLY A CA   1 
ATOM   1864 C  C    . GLY A 1 253 ? 89.962  103.245 135.392 1.00 111.09 ? 253 GLY A C    1 
ATOM   1865 O  O    . GLY A 1 253 ? 90.587  103.619 136.388 1.00 111.09 ? 253 GLY A O    1 
ATOM   1866 N  N    . LYS A 1 254 ? 89.143  104.044 134.719 1.00 114.62 ? 254 LYS A N    1 
ATOM   1867 C  CA   . LYS A 1 254 ? 88.912  105.430 135.103 1.00 114.62 ? 254 LYS A CA   1 
ATOM   1868 C  C    . LYS A 1 254 ? 87.481  105.782 134.715 1.00 114.62 ? 254 LYS A C    1 
ATOM   1869 O  O    . LYS A 1 254 ? 86.646  104.892 134.517 1.00 114.62 ? 254 LYS A O    1 
ATOM   1870 C  CB   . LYS A 1 254 ? 89.955  106.357 134.459 1.00 114.62 ? 254 LYS A CB   1 
ATOM   1871 C  CG   . LYS A 1 254 ? 90.417  107.490 135.360 1.00 114.62 ? 254 LYS A CG   1 
ATOM   1872 C  CD   . LYS A 1 254 ? 91.083  106.953 136.615 1.00 114.62 ? 254 LYS A CD   1 
ATOM   1873 C  CE   . LYS A 1 254 ? 92.439  106.340 136.304 1.00 114.62 ? 254 LYS A CE   1 
ATOM   1874 N  NZ   . LYS A 1 254 ? 93.111  105.832 137.532 1.00 114.62 ? 254 LYS A NZ   1 
ATOM   1875 N  N    . ASN A 1 255 ? 87.192  107.082 134.626 1.00 116.98 ? 255 ASN A N    1 
ATOM   1876 C  CA   . ASN A 1 255 ? 85.838  107.525 134.314 1.00 116.98 ? 255 ASN A CA   1 
ATOM   1877 C  C    . ASN A 1 255 ? 85.403  107.056 132.931 1.00 116.98 ? 255 ASN A C    1 
ATOM   1878 O  O    . ASN A 1 255 ? 84.249  106.653 132.743 1.00 116.98 ? 255 ASN A O    1 
ATOM   1879 C  CB   . ASN A 1 255 ? 85.755  109.045 134.424 1.00 116.98 ? 255 ASN A CB   1 
ATOM   1880 C  CG   . ASN A 1 255 ? 86.181  109.551 135.788 1.00 116.98 ? 255 ASN A CG   1 
ATOM   1881 O  OD1  . ASN A 1 255 ? 85.822  108.976 136.814 1.00 116.98 ? 255 ASN A OD1  1 
ATOM   1882 N  ND2  . ASN A 1 255 ? 86.960  110.626 135.802 1.00 116.98 ? 255 ASN A ND2  1 
ATOM   1883 N  N    . GLY A 1 256 ? 86.304  107.100 131.957 1.00 110.54 ? 256 GLY A N    1 
ATOM   1884 C  CA   . GLY A 1 256 ? 85.974  106.611 130.633 1.00 110.54 ? 256 GLY A CA   1 
ATOM   1885 C  C    . GLY A 1 256 ? 87.116  105.933 129.905 1.00 110.54 ? 256 GLY A C    1 
ATOM   1886 O  O    . GLY A 1 256 ? 86.994  105.612 128.719 1.00 110.54 ? 256 GLY A O    1 
ATOM   1887 N  N    . SER A 1 257 ? 88.229  105.700 130.594 1.00 101.95 ? 257 SER A N    1 
ATOM   1888 C  CA   . SER A 1 257 ? 89.423  105.181 129.950 1.00 101.95 ? 257 SER A CA   1 
ATOM   1889 C  C    . SER A 1 257 ? 89.429  103.655 130.007 1.00 101.95 ? 257 SER A C    1 
ATOM   1890 O  O    . SER A 1 257 ? 88.429  103.014 130.341 1.00 101.95 ? 257 SER A O    1 
ATOM   1891 C  CB   . SER A 1 257 ? 90.676  105.758 130.598 1.00 101.95 ? 257 SER A CB   1 
ATOM   1892 O  OG   . SER A 1 257 ? 91.020  105.020 131.754 1.00 101.95 ? 257 SER A OG   1 
ATOM   1893 N  N    . THR A 1 258 ? 90.571  103.061 129.676 1.00 93.37  ? 258 THR A N    1 
ATOM   1894 C  CA   . THR A 1 258 ? 90.713  101.619 129.602 1.00 93.37  ? 258 THR A CA   1 
ATOM   1895 C  C    . THR A 1 258 ? 91.231  101.067 130.929 1.00 93.37  ? 258 THR A C    1 
ATOM   1896 O  O    . THR A 1 258 ? 91.403  101.794 131.909 1.00 93.37  ? 258 THR A O    1 
ATOM   1897 C  CB   . THR A 1 258 ? 91.635  101.242 128.447 1.00 93.37  ? 258 THR A CB   1 
ATOM   1898 O  OG1  . THR A 1 258 ? 91.478  99.853  128.146 1.00 93.37  ? 258 THR A OG1  1 
ATOM   1899 C  CG2  . THR A 1 258 ? 93.092  101.512 128.804 1.00 93.37  ? 258 THR A CG2  1 
ATOM   1900 N  N    . ILE A 1 259 ? 91.494  99.757  130.956 1.00 88.06  ? 259 ILE A N    1 
ATOM   1901 C  CA   . ILE A 1 259 ? 91.919  99.096  132.184 1.00 88.06  ? 259 ILE A CA   1 
ATOM   1902 C  C    . ILE A 1 259 ? 93.319  99.509  132.614 1.00 88.06  ? 259 ILE A C    1 
ATOM   1903 O  O    . ILE A 1 259 ? 93.713  99.251  133.757 1.00 88.06  ? 259 ILE A O    1 
ATOM   1904 C  CB   . ILE A 1 259 ? 91.821  97.569  132.018 1.00 88.06  ? 259 ILE A CB   1 
ATOM   1905 C  CG1  . ILE A 1 259 ? 91.494  96.909  133.355 1.00 88.06  ? 259 ILE A CG1  1 
ATOM   1906 C  CG2  . ILE A 1 259 ? 93.103  97.005  131.443 1.00 88.06  ? 259 ILE A CG2  1 
ATOM   1907 C  CD1  . ILE A 1 259 ? 91.041  95.482  133.224 1.00 88.06  ? 259 ILE A CD1  1 
ATOM   1908 N  N    . ALA A 1 260 ? 94.092  100.150 131.738 1.00 85.07  ? 260 ALA A N    1 
ATOM   1909 C  CA   . ALA A 1 260 ? 95.399  100.677 132.106 1.00 85.07  ? 260 ALA A CA   1 
ATOM   1910 C  C    . ALA A 1 260 ? 95.417  102.200 132.159 1.00 85.07  ? 260 ALA A C    1 
ATOM   1911 O  O    . ALA A 1 260 ? 96.486  102.792 132.333 1.00 85.07  ? 260 ALA A O    1 
ATOM   1912 C  CB   . ALA A 1 260 ? 96.468  100.169 131.137 1.00 85.07  ? 260 ALA A CB   1 
ATOM   1913 N  N    . GLY A 1 261 ? 94.261  102.846 132.015 1.00 86.03  ? 261 GLY A N    1 
ATOM   1914 C  CA   . GLY A 1 261 ? 94.177  104.289 132.032 1.00 86.03  ? 261 GLY A CA   1 
ATOM   1915 C  C    . GLY A 1 261 ? 94.426  104.956 130.697 1.00 86.03  ? 261 GLY A C    1 
ATOM   1916 O  O    . GLY A 1 261 ? 94.222  106.170 130.580 1.00 86.03  ? 261 GLY A O    1 
ATOM   1917 N  N    . THR A 1 262 ? 94.849  104.201 129.691 1.00 83.44  ? 262 THR A N    1 
ATOM   1918 C  CA   . THR A 1 262 ? 95.135  104.755 128.379 1.00 83.44  ? 262 THR A CA   1 
ATOM   1919 C  C    . THR A 1 262 ? 93.827  105.109 127.675 1.00 83.44  ? 262 THR A C    1 
ATOM   1920 O  O    . THR A 1 262 ? 92.777  104.526 127.948 1.00 83.44  ? 262 THR A O    1 
ATOM   1921 C  CB   . THR A 1 262 ? 95.955  103.740 127.578 1.00 83.44  ? 262 THR A CB   1 
ATOM   1922 O  OG1  . THR A 1 262 ? 97.169  103.474 128.283 1.00 83.44  ? 262 THR A OG1  1 
ATOM   1923 C  CG2  . THR A 1 262 ? 96.329  104.259 126.198 1.00 83.44  ? 262 THR A CG2  1 
ATOM   1924 N  N    . SER A 1 263 ? 93.884  106.112 126.800 1.00 85.03  ? 263 SER A N    1 
ATOM   1925 C  CA   . SER A 1 263 ? 92.712  106.515 126.036 1.00 85.03  ? 263 SER A CA   1 
ATOM   1926 C  C    . SER A 1 263 ? 92.188  105.349 125.208 1.00 85.03  ? 263 SER A C    1 
ATOM   1927 O  O    . SER A 1 263 ? 92.958  104.539 124.688 1.00 85.03  ? 263 SER A O    1 
ATOM   1928 C  CB   . SER A 1 263 ? 93.053  107.696 125.130 1.00 85.03  ? 263 SER A CB   1 
ATOM   1929 O  OG   . SER A 1 263 ? 94.177  107.405 124.317 1.00 85.03  ? 263 SER A OG   1 
ATOM   1930 N  N    . VAL A 1 264 ? 90.860  105.262 125.107 1.00 80.06  ? 264 VAL A N    1 
ATOM   1931 C  CA   . VAL A 1 264 ? 90.224  104.101 124.500 1.00 80.06  ? 264 VAL A CA   1 
ATOM   1932 C  C    . VAL A 1 264 ? 90.535  103.980 123.019 1.00 80.06  ? 264 VAL A C    1 
ATOM   1933 O  O    . VAL A 1 264 ? 90.517  102.869 122.479 1.00 80.06  ? 264 VAL A O    1 
ATOM   1934 C  CB   . VAL A 1 264 ? 88.703  104.147 124.729 1.00 80.06  ? 264 VAL A CB   1 
ATOM   1935 C  CG1  . VAL A 1 264 ? 88.397  104.078 126.203 1.00 80.06  ? 264 VAL A CG1  1 
ATOM   1936 C  CG2  . VAL A 1 264 ? 88.111  105.405 124.132 1.00 80.06  ? 264 VAL A CG2  1 
ATOM   1937 N  N    . LEU A 1 265 ? 90.829  105.079 122.345 1.00 78.33  ? 265 LEU A N    1 
ATOM   1938 C  CA   . LEU A 1 265 ? 91.070  105.035 120.914 1.00 78.33  ? 265 LEU A CA   1 
ATOM   1939 C  C    . LEU A 1 265 ? 92.532  104.802 120.567 1.00 78.33  ? 265 LEU A C    1 
ATOM   1940 O  O    . LEU A 1 265 ? 92.865  104.726 119.382 1.00 78.33  ? 265 LEU A O    1 
ATOM   1941 C  CB   . LEU A 1 265 ? 90.580  106.329 120.264 1.00 78.33  ? 265 LEU A CB   1 
ATOM   1942 C  CG   . LEU A 1 265 ? 89.125  106.690 120.567 1.00 78.33  ? 265 LEU A CG   1 
ATOM   1943 C  CD1  . LEU A 1 265 ? 88.698  107.899 119.756 1.00 78.33  ? 265 LEU A CD1  1 
ATOM   1944 C  CD2  . LEU A 1 265 ? 88.203  105.515 120.295 1.00 78.33  ? 265 LEU A CD2  1 
ATOM   1945 N  N    . SER A 1 266 ? 93.407  104.702 121.563 1.00 75.42  ? 266 SER A N    1 
ATOM   1946 C  CA   . SER A 1 266 ? 94.826  104.477 121.288 1.00 75.42  ? 266 SER A CA   1 
ATOM   1947 C  C    . SER A 1 266 ? 95.128  103.148 120.604 1.00 75.42  ? 266 SER A C    1 
ATOM   1948 O  O    . SER A 1 266 ? 95.878  103.160 119.613 1.00 75.42  ? 266 SER A O    1 
ATOM   1949 C  CB   . SER A 1 266 ? 95.634  104.630 122.579 1.00 75.42  ? 266 SER A CB   1 
ATOM   1950 O  OG   . SER A 1 266 ? 97.008  104.370 122.351 1.00 75.42  ? 266 SER A OG   1 
ATOM   1951 N  N    . PRO A 1 267 ? 94.627  101.985 121.057 1.00 67.30  ? 267 PRO A N    1 
ATOM   1952 C  CA   . PRO A 1 267 ? 95.036  100.730 120.407 1.00 67.30  ? 267 PRO A CA   1 
ATOM   1953 C  C    . PRO A 1 267 ? 94.570  100.594 118.977 1.00 67.30  ? 267 PRO A C    1 
ATOM   1954 O  O    . PRO A 1 267 ? 95.149  99.791  118.236 1.00 67.30  ? 267 PRO A O    1 
ATOM   1955 C  CB   . PRO A 1 267 ? 94.403  99.651  121.292 1.00 67.30  ? 267 PRO A CB   1 
ATOM   1956 C  CG   . PRO A 1 267 ? 94.164  100.310 122.564 1.00 67.30  ? 267 PRO A CG   1 
ATOM   1957 C  CD   . PRO A 1 267 ? 93.759  101.690 122.207 1.00 67.30  ? 267 PRO A CD   1 
ATOM   1958 N  N    . GLY A 1 268 ? 93.554  101.344 118.559 1.00 64.50  ? 268 GLY A N    1 
ATOM   1959 C  CA   . GLY A 1 268 ? 93.141  101.299 117.171 1.00 64.50  ? 268 GLY A CA   1 
ATOM   1960 C  C    . GLY A 1 268 ? 94.184  101.824 116.212 1.00 64.50  ? 268 GLY A C    1 
ATOM   1961 O  O    . GLY A 1 268 ? 94.150  101.470 115.031 1.00 64.50  ? 268 GLY A O    1 
ATOM   1962 N  N    . LEU A 1 269 ? 95.116  102.649 116.699 1.00 64.47  ? 269 LEU A N    1 
ATOM   1963 C  CA   . LEU A 1 269 ? 96.152  103.206 115.840 1.00 64.47  ? 269 LEU A CA   1 
ATOM   1964 C  C    . LEU A 1 269 ? 97.044  102.130 115.249 1.00 64.47  ? 269 LEU A C    1 
ATOM   1965 O  O    . LEU A 1 269 ? 97.501  102.271 114.112 1.00 64.47  ? 269 LEU A O    1 
ATOM   1966 C  CB   . LEU A 1 269 ? 97.006  104.209 116.610 1.00 64.47  ? 269 LEU A CB   1 
ATOM   1967 C  CG   . LEU A 1 269 ? 96.599  105.675 116.533 1.00 64.47  ? 269 LEU A CG   1 
ATOM   1968 C  CD1  . LEU A 1 269 ? 95.345  105.934 117.341 1.00 64.47  ? 269 LEU A CD1  1 
ATOM   1969 C  CD2  . LEU A 1 269 ? 97.741  106.547 117.022 1.00 64.47  ? 269 LEU A CD2  1 
ATOM   1970 N  N    . HIS A 1 270 ? 97.310  101.057 115.995 1.00 61.20  ? 270 HIS A N    1 
ATOM   1971 C  CA   . HIS A 1 270 ? 98.178  100.000 115.488 1.00 61.20  ? 270 HIS A CA   1 
ATOM   1972 C  C    . HIS A 1 270 ? 97.576  99.328  114.260 1.00 61.20  ? 270 HIS A C    1 
ATOM   1973 O  O    . HIS A 1 270 ? 98.217  99.243  113.198 1.00 61.20  ? 270 HIS A O    1 
ATOM   1974 C  CB   . HIS A 1 270 ? 98.422  98.968  116.580 1.00 61.20  ? 270 HIS A CB   1 
ATOM   1975 C  CG   . HIS A 1 270 ? 99.338  99.433  117.664 1.00 61.20  ? 270 HIS A CG   1 
ATOM   1976 N  ND1  . HIS A 1 270 ? 99.087  99.206  118.998 1.00 61.20  ? 270 HIS A ND1  1 
ATOM   1977 C  CD2  . HIS A 1 270 ? 100.515 100.095 117.609 1.00 61.20  ? 270 HIS A CD2  1 
ATOM   1978 C  CE1  . HIS A 1 270 ? 100.064 99.720  119.720 1.00 61.20  ? 270 HIS A CE1  1 
ATOM   1979 N  NE2  . HIS A 1 270 ? 100.944 100.267 118.902 1.00 61.20  ? 270 HIS A NE2  1 
ATOM   1980 N  N    . ILE A 1 271 ? 96.333  98.863  114.375 1.00 54.28  ? 271 ILE A N    1 
ATOM   1981 C  CA   . ILE A 1 271 ? 95.728  98.179  113.244 1.00 54.28  ? 271 ILE A CA   1 
ATOM   1982 C  C    . ILE A 1 271 ? 95.387  99.172  112.147 1.00 54.28  ? 271 ILE A C    1 
ATOM   1983 O  O    . ILE A 1 271 ? 95.389  98.816  110.962 1.00 54.28  ? 271 ILE A O    1 
ATOM   1984 C  CB   . ILE A 1 271 ? 94.504  97.358  113.687 1.00 54.28  ? 271 ILE A CB   1 
ATOM   1985 C  CG1  . ILE A 1 271 ? 94.197  96.301  112.638 1.00 54.28  ? 271 ILE A CG1  1 
ATOM   1986 C  CG2  . ILE A 1 271 ? 93.299  98.242  113.922 1.00 54.28  ? 271 ILE A CG2  1 
ATOM   1987 C  CD1  . ILE A 1 271 ? 95.380  95.418  112.328 1.00 54.28  ? 271 ILE A CD1  1 
ATOM   1988 N  N    . GLY A 1 272 ? 95.140  100.436 112.503 1.00 54.88  ? 272 GLY A N    1 
ATOM   1989 C  CA   . GLY A 1 272 ? 94.951  101.446 111.482 1.00 54.88  ? 272 GLY A CA   1 
ATOM   1990 C  C    . GLY A 1 272 ? 96.202  101.661 110.658 1.00 54.88  ? 272 GLY A C    1 
ATOM   1991 O  O    . GLY A 1 272 ? 96.138  101.747 109.432 1.00 54.88  ? 272 GLY A O    1 
ATOM   1992 N  N    . LEU A 1 273 ? 97.358  101.720 111.316 1.00 50.66  ? 273 LEU A N    1 
ATOM   1993 C  CA   . LEU A 1 273 ? 98.607  101.901 110.591 1.00 50.66  ? 273 LEU A CA   1 
ATOM   1994 C  C    . LEU A 1 273 ? 98.909  100.689 109.723 1.00 50.66  ? 273 LEU A C    1 
ATOM   1995 O  O    . LEU A 1 273 ? 99.375  100.841 108.588 1.00 50.66  ? 273 LEU A O    1 
ATOM   1996 C  CB   . LEU A 1 273 ? 99.745  102.178 111.570 1.00 50.66  ? 273 LEU A CB   1 
ATOM   1997 C  CG   . LEU A 1 273 ? 101.051 102.743 111.008 1.00 50.66  ? 273 LEU A CG   1 
ATOM   1998 C  CD1  . LEU A 1 273 ? 101.689 103.650 112.030 1.00 50.66  ? 273 LEU A CD1  1 
ATOM   1999 C  CD2  . LEU A 1 273 ? 102.022 101.653 110.630 1.00 50.66  ? 273 LEU A CD2  1 
ATOM   2000 N  N    . ILE A 1 274 ? 98.636  99.482  110.224 1.00 47.65  ? 274 ILE A N    1 
ATOM   2001 C  CA   . ILE A 1 274 ? 98.886  98.286  109.416 1.00 47.65  ? 274 ILE A CA   1 
ATOM   2002 C  C    . ILE A 1 274 ? 97.996  98.273  108.178 1.00 47.65  ? 274 ILE A C    1 
ATOM   2003 O  O    . ILE A 1 274 ? 98.467  98.042  107.056 1.00 47.65  ? 274 ILE A O    1 
ATOM   2004 C  CB   . ILE A 1 274 ? 98.700  97.015  110.256 1.00 47.65  ? 274 ILE A CB   1 
ATOM   2005 C  CG1  . ILE A 1 274 ? 99.942  96.752  111.092 1.00 47.65  ? 274 ILE A CG1  1 
ATOM   2006 C  CG2  . ILE A 1 274 ? 98.459  95.823  109.368 1.00 47.65  ? 274 ILE A CG2  1 
ATOM   2007 C  CD1  . ILE A 1 274 ? 99.842  95.500  111.914 1.00 47.65  ? 274 ILE A CD1  1 
ATOM   2008 N  N    . ILE A 1 275 ? 96.702  98.550  108.352 1.00 47.11  ? 275 ILE A N    1 
ATOM   2009 C  CA   . ILE A 1 275 ? 95.788  98.518  107.215 1.00 47.11  ? 275 ILE A CA   1 
ATOM   2010 C  C    . ILE A 1 275 ? 96.104  99.640  106.232 1.00 47.11  ? 275 ILE A C    1 
ATOM   2011 O  O    . ILE A 1 275 ? 96.044  99.446  105.014 1.00 47.11  ? 275 ILE A O    1 
ATOM   2012 C  CB   . ILE A 1 275 ? 94.332  98.564  107.709 1.00 47.11  ? 275 ILE A CB   1 
ATOM   2013 C  CG1  . ILE A 1 275 ? 93.892  97.169  108.133 1.00 47.11  ? 275 ILE A CG1  1 
ATOM   2014 C  CG2  . ILE A 1 275 ? 93.397  99.085  106.639 1.00 47.11  ? 275 ILE A CG2  1 
ATOM   2015 C  CD1  . ILE A 1 275 ? 92.495  97.122  108.673 1.00 47.11  ? 275 ILE A CD1  1 
ATOM   2016 N  N    . ILE A 1 276 ? 96.491  100.812 106.733 1.00 44.56  ? 276 ILE A N    1 
ATOM   2017 C  CA   . ILE A 1 276 ? 96.818  101.923 105.848 1.00 44.56  ? 276 ILE A CA   1 
ATOM   2018 C  C    . ILE A 1 276 ? 98.094  101.637 105.059 1.00 44.56  ? 276 ILE A C    1 
ATOM   2019 O  O    . ILE A 1 276 ? 98.180  101.947 103.861 1.00 44.56  ? 276 ILE A O    1 
ATOM   2020 C  CB   . ILE A 1 276 ? 96.901  103.223 106.664 1.00 44.56  ? 276 ILE A CB   1 
ATOM   2021 C  CG1  . ILE A 1 276 ? 95.498  103.694 107.031 1.00 44.56  ? 276 ILE A CG1  1 
ATOM   2022 C  CG2  . ILE A 1 276 ? 97.594  104.301 105.908 1.00 44.56  ? 276 ILE A CG2  1 
ATOM   2023 C  CD1  . ILE A 1 276 ? 94.638  104.000 105.843 1.00 44.56  ? 276 ILE A CD1  1 
ATOM   2024 N  N    . LEU A 1 277 ? 99.094  101.023 105.696 1.00 42.44  ? 277 LEU A N    1 
ATOM   2025 C  CA   . LEU A 1 277 ? 100.280 100.616 104.952 1.00 42.44  ? 277 LEU A CA   1 
ATOM   2026 C  C    . LEU A 1 277 ? 99.935  99.581  103.891 1.00 42.44  ? 277 LEU A C    1 
ATOM   2027 O  O    . LEU A 1 277 ? 100.476 99.617  102.778 1.00 42.44  ? 277 LEU A O    1 
ATOM   2028 C  CB   . LEU A 1 277 ? 101.348 100.066 105.890 1.00 42.44  ? 277 LEU A CB   1 
ATOM   2029 C  CG   . LEU A 1 277 ? 102.220 101.091 106.602 1.00 42.44  ? 277 LEU A CG   1 
ATOM   2030 C  CD1  . LEU A 1 277 ? 103.349 100.393 107.317 1.00 42.44  ? 277 LEU A CD1  1 
ATOM   2031 C  CD2  . LEU A 1 277 ? 102.756 102.085 105.611 1.00 42.44  ? 277 LEU A CD2  1 
ATOM   2032 N  N    . ALA A 1 278 ? 99.039  98.651  104.215 1.00 44.58  ? 278 ALA A N    1 
ATOM   2033 C  CA   . ALA A 1 278 ? 98.623  97.667  103.222 1.00 44.58  ? 278 ALA A CA   1 
ATOM   2034 C  C    . ALA A 1 278 ? 97.918  98.327  102.046 1.00 44.58  ? 278 ALA A C    1 
ATOM   2035 O  O    . ALA A 1 278 ? 98.142  97.951  100.892 1.00 44.58  ? 278 ALA A O    1 
ATOM   2036 C  CB   . ALA A 1 278 ? 97.726  96.620  103.865 1.00 44.58  ? 278 ALA A CB   1 
ATOM   2037 N  N    . ILE A 1 279 ? 97.075  99.326  102.318 1.00 43.22  ? 279 ILE A N    1 
ATOM   2038 C  CA   . ILE A 1 279 ? 96.395  100.050 101.244 1.00 43.22  ? 279 ILE A CA   1 
ATOM   2039 C  C    . ILE A 1 279 ? 97.400  100.754 100.341 1.00 43.22  ? 279 ILE A C    1 
ATOM   2040 O  O    . ILE A 1 279 ? 97.306  100.676 99.107  1.00 43.22  ? 279 ILE A O    1 
ATOM   2041 C  CB   . ILE A 1 279 ? 95.377  101.045 101.821 1.00 43.22  ? 279 ILE A CB   1 
ATOM   2042 C  CG1  . ILE A 1 279 ? 94.259  100.323 102.556 1.00 43.22  ? 279 ILE A CG1  1 
ATOM   2043 C  CG2  . ILE A 1 279 ? 94.785  101.891 100.723 1.00 43.22  ? 279 ILE A CG2  1 
ATOM   2044 C  CD1  . ILE A 1 279 ? 93.438  99.469  101.671 1.00 43.22  ? 279 ILE A CD1  1 
ATOM   2045 N  N    . MET A 1 280 ? 98.375  101.455 100.931 1.00 45.27  ? 280 MET A N    1 
ATOM   2046 C  CA   . MET A 1 280 ? 99.352  102.150 100.095 1.00 45.27  ? 280 MET A CA   1 
ATOM   2047 C  C    . MET A 1 280 ? 100.185 101.183 99.263  1.00 45.27  ? 280 MET A C    1 
ATOM   2048 O  O    . MET A 1 280 ? 100.401 101.411 98.068  1.00 45.27  ? 280 MET A O    1 
ATOM   2049 C  CB   . MET A 1 280 ? 100.272 103.061 100.907 1.00 45.27  ? 280 MET A CB   1 
ATOM   2050 C  CG   . MET A 1 280 ? 99.630  104.261 101.553 1.00 45.27  ? 280 MET A CG   1 
ATOM   2051 S  SD   . MET A 1 280 ? 100.700 104.947 102.823 1.00 45.27  ? 280 MET A SD   1 
ATOM   2052 C  CE   . MET A 1 280 ? 99.599  106.112 103.600 1.00 45.27  ? 280 MET A CE   1 
ATOM   2053 N  N    . ILE A 1 281 ? 100.667 100.096 99.863  1.00 42.07  ? 281 ILE A N    1 
ATOM   2054 C  CA   . ILE A 1 281 ? 101.538 99.223  99.084  1.00 42.07  ? 281 ILE A CA   1 
ATOM   2055 C  C    . ILE A 1 281 ? 100.734 98.437  98.050  1.00 42.07  ? 281 ILE A C    1 
ATOM   2056 O  O    . ILE A 1 281 ? 101.265 98.065  96.998  1.00 42.07  ? 281 ILE A O    1 
ATOM   2057 C  CB   . ILE A 1 281 ? 102.358 98.319  100.015 1.00 42.07  ? 281 ILE A CB   1 
ATOM   2058 C  CG1  . ILE A 1 281 ? 103.126 99.179  101.003 1.00 42.07  ? 281 ILE A CG1  1 
ATOM   2059 C  CG2  . ILE A 1 281 ? 103.379 97.529  99.244  1.00 42.07  ? 281 ILE A CG2  1 
ATOM   2060 C  CD1  . ILE A 1 281 ? 103.876 98.387  102.021 1.00 42.07  ? 281 ILE A CD1  1 
ATOM   2061 N  N    . TYR A 1 282 ? 99.446  98.204  98.298  1.00 50.19  ? 282 TYR A N    1 
ATOM   2062 C  CA   . TYR A 1 282 ? 98.563  97.737  97.236  1.00 50.19  ? 282 TYR A CA   1 
ATOM   2063 C  C    . TYR A 1 282 ? 98.495  98.720  96.083  1.00 50.19  ? 282 TYR A C    1 
ATOM   2064 O  O    . TYR A 1 282 ? 98.781  98.364  94.935  1.00 50.19  ? 282 TYR A O    1 
ATOM   2065 C  CB   . TYR A 1 282 ? 97.162  97.506  97.789  1.00 50.19  ? 282 TYR A CB   1 
ATOM   2066 C  CG   . TYR A 1 282 ? 96.245  96.754  96.865  1.00 50.19  ? 282 TYR A CG   1 
ATOM   2067 C  CD1  . TYR A 1 282 ? 96.731  95.867  95.922  1.00 50.19  ? 282 TYR A CD1  1 
ATOM   2068 C  CD2  . TYR A 1 282 ? 94.882  96.990  96.895  1.00 50.19  ? 282 TYR A CD2  1 
ATOM   2069 C  CE1  . TYR A 1 282 ? 95.875  95.216  95.063  1.00 50.19  ? 282 TYR A CE1  1 
ATOM   2070 C  CE2  . TYR A 1 282 ? 94.025  96.339  96.048  1.00 50.19  ? 282 TYR A CE2  1 
ATOM   2071 C  CZ   . TYR A 1 282 ? 94.524  95.451  95.135  1.00 50.19  ? 282 TYR A CZ   1 
ATOM   2072 O  OH   . TYR A 1 282 ? 93.659  94.800  94.287  1.00 50.19  ? 282 TYR A OH   1 
ATOM   2073 N  N    . LYS A 1 283 ? 98.128  99.963  96.364  1.00 45.18  ? 283 LYS A N    1 
ATOM   2074 C  CA   . LYS A 1 283 ? 97.718  100.837 95.274  1.00 45.18  ? 283 LYS A CA   1 
ATOM   2075 C  C    . LYS A 1 283 ? 98.909  101.408 94.515  1.00 45.18  ? 283 LYS A C    1 
ATOM   2076 O  O    . LYS A 1 283 ? 98.832  101.605 93.299  1.00 45.18  ? 283 LYS A O    1 
ATOM   2077 C  CB   . LYS A 1 283 ? 96.829  101.952 95.812  1.00 45.18  ? 283 LYS A CB   1 
ATOM   2078 C  CG   . LYS A 1 283 ? 95.432  101.478 96.157  1.00 45.18  ? 283 LYS A CG   1 
ATOM   2079 C  CD   . LYS A 1 283 ? 94.789  100.750 94.994  1.00 45.18  ? 283 LYS A CD   1 
ATOM   2080 C  CE   . LYS A 1 283 ? 93.276  100.761 95.105  1.00 45.18  ? 283 LYS A CE   1 
ATOM   2081 N  NZ   . LYS A 1 283 ? 92.623  100.793 93.768  1.00 45.18  ? 283 LYS A NZ   1 
ATOM   2082 N  N    . LYS A 1 284 ? 100.019 101.668 95.203  1.00 48.45  ? 284 LYS A N    1 
ATOM   2083 C  CA   . LYS A 1 284 ? 101.124 102.379 94.568  1.00 48.45  ? 284 LYS A CA   1 
ATOM   2084 C  C    . LYS A 1 284 ? 101.923 101.487 93.624  1.00 48.45  ? 284 LYS A C    1 
ATOM   2085 O  O    . LYS A 1 284 ? 102.467 101.987 92.634  1.00 48.45  ? 284 LYS A O    1 
ATOM   2086 C  CB   . LYS A 1 284 ? 102.033 102.980 95.641  1.00 48.45  ? 284 LYS A CB   1 
ATOM   2087 C  CG   . LYS A 1 284 ? 103.294 103.676 95.134  1.00 48.45  ? 284 LYS A CG   1 
ATOM   2088 C  CD   . LYS A 1 284 ? 102.990 104.775 94.130  1.00 48.45  ? 284 LYS A CD   1 
ATOM   2089 C  CE   . LYS A 1 284 ? 104.227 105.153 93.326  1.00 48.45  ? 284 LYS A CE   1 
ATOM   2090 N  NZ   . LYS A 1 284 ? 104.766 104.026 92.532  1.00 48.45  ? 284 LYS A NZ   1 
ATOM   2091 N  N    . SER A 1 285 ? 101.977 100.180 93.888  1.00 51.71  ? 285 SER A N    1 
ATOM   2092 C  CA   . SER A 1 285 ? 102.926 99.276  93.237  1.00 51.71  ? 285 SER A CA   1 
ATOM   2093 C  C    . SER A 1 285 ? 102.873 99.323  91.717  1.00 51.71  ? 285 SER A C    1 
ATOM   2094 O  O    . SER A 1 285 ? 101.885 98.901  91.111  1.00 51.71  ? 285 SER A O    1 
ATOM   2095 C  CB   . SER A 1 285 ? 102.686 97.841  93.692  1.00 51.71  ? 285 SER A CB   1 
ATOM   2096 O  OG   . SER A 1 285 ? 103.738 97.007  93.251  1.00 51.71  ? 285 SER A OG   1 
ATOM   2097 N  N    . ALA A 1 286 ? 103.938 99.840  91.101  1.00 61.55  ? 286 ALA A N    1 
ATOM   2098 C  CA   . ALA A 1 286 ? 103.988 99.928  89.646  1.00 61.55  ? 286 ALA A CA   1 
ATOM   2099 C  C    . ALA A 1 286 ? 104.107 98.546  89.024  1.00 61.55  ? 286 ALA A C    1 
ATOM   2100 O  O    . ALA A 1 286 ? 103.357 98.197  88.108  1.00 61.55  ? 286 ALA A O    1 
ATOM   2101 C  CB   . ALA A 1 286 ? 105.150 100.819 89.210  1.00 61.55  ? 286 ALA A CB   1 
ATOM   2102 N  N    . THR A 1 287 ? 105.040 97.743  89.519  1.00 64.59  ? 287 THR A N    1 
ATOM   2103 C  CA   . THR A 1 287 ? 105.043 96.323  89.215  1.00 64.59  ? 287 THR A CA   1 
ATOM   2104 C  C    . THR A 1 287 ? 103.979 95.672  90.083  1.00 64.59  ? 287 THR A C    1 
ATOM   2105 O  O    . THR A 1 287 ? 103.971 95.861  91.303  1.00 64.59  ? 287 THR A O    1 
ATOM   2106 C  CB   . THR A 1 287 ? 106.415 95.713  89.478  1.00 64.59  ? 287 THR A CB   1 
ATOM   2107 O  OG1  . THR A 1 287 ? 107.392 96.363  88.657  1.00 64.59  ? 287 THR A OG1  1 
ATOM   2108 C  CG2  . THR A 1 287 ? 106.408 94.235  89.157  1.00 64.59  ? 287 THR A CG2  1 
ATOM   2109 N  N    . ASP A 1 288 ? 103.066 94.937  89.463  1.00 67.80  ? 288 ASP A N    1 
ATOM   2110 C  CA   . ASP A 1 288 ? 101.954 94.355  90.204  1.00 67.80  ? 288 ASP A CA   1 
ATOM   2111 C  C    . ASP A 1 288 ? 102.460 93.197  91.049  1.00 67.80  ? 288 ASP A C    1 
ATOM   2112 O  O    . ASP A 1 288 ? 102.722 92.108  90.530  1.00 67.80  ? 288 ASP A O    1 
ATOM   2113 C  CB   . ASP A 1 288 ? 100.862 93.901  89.243  1.00 67.80  ? 288 ASP A CB   1 
ATOM   2114 C  CG   . ASP A 1 288 ? 100.168 95.060  88.571  1.00 67.80  ? 288 ASP A CG   1 
ATOM   2115 O  OD1  . ASP A 1 288 ? 99.865  96.048  89.269  1.00 67.80  ? 288 ASP A OD1  1 
ATOM   2116 O  OD2  . ASP A 1 288 ? 99.927  94.985  87.348  1.00 67.80  ? 288 ASP A OD2  1 
ATOM   2117 N  N    . VAL A 1 289 ? 102.628 93.435  92.350  1.00 63.22  ? 289 VAL A N    1 
ATOM   2118 C  CA   . VAL A 1 289 ? 103.082 92.373  93.240  1.00 63.22  ? 289 VAL A CA   1 
ATOM   2119 C  C    . VAL A 1 289 ? 101.991 91.319  93.423  1.00 63.22  ? 289 VAL A C    1 
ATOM   2120 O  O    . VAL A 1 289 ? 102.281 90.121  93.540  1.00 63.22  ? 289 VAL A O    1 
ATOM   2121 C  CB   . VAL A 1 289 ? 103.554 92.975  94.575  1.00 63.22  ? 289 VAL A CB   1 
ATOM   2122 C  CG1  . VAL A 1 289 ? 102.482 93.845  95.181  1.00 63.22  ? 289 VAL A CG1  1 
ATOM   2123 C  CG2  . VAL A 1 289 ? 103.988 91.894  95.534  1.00 63.22  ? 289 VAL A CG2  1 
ATOM   2124 N  N    . PHE A 1 290 ? 100.718 91.727  93.369  1.00 62.39  ? 290 PHE A N    1 
ATOM   2125 C  CA   . PHE A 1 290 ? 99.636  90.779  93.634  1.00 62.39  ? 290 PHE A CA   1 
ATOM   2126 C  C    . PHE A 1 290 ? 99.423  89.807  92.489  1.00 62.39  ? 290 PHE A C    1 
ATOM   2127 O  O    . PHE A 1 290 ? 99.410  88.591  92.694  1.00 62.39  ? 290 PHE A O    1 
ATOM   2128 C  CB   . PHE A 1 290 ? 98.321  91.493  93.920  1.00 62.39  ? 290 PHE A CB   1 
ATOM   2129 C  CG   . PHE A 1 290 ? 98.171  91.921  95.330  1.00 62.39  ? 290 PHE A CG   1 
ATOM   2130 C  CD1  . PHE A 1 290 ? 99.250  91.953  96.172  1.00 62.39  ? 290 PHE A CD1  1 
ATOM   2131 C  CD2  . PHE A 1 290 ? 96.915  92.152  95.850  1.00 62.39  ? 290 PHE A CD2  1 
ATOM   2132 C  CE1  . PHE A 1 290 ? 99.097  92.308  97.470  1.00 62.39  ? 290 PHE A CE1  1 
ATOM   2133 C  CE2  . PHE A 1 290 ? 96.753  92.502  97.157  1.00 62.39  ? 290 PHE A CE2  1 
ATOM   2134 C  CZ   . PHE A 1 290 ? 97.846  92.579  97.973  1.00 62.39  ? 290 PHE A CZ   1 
ATOM   2135 N  N    . GLU A 1 291 ? 99.234  90.315  91.276  1.00 75.68  ? 291 GLU A N    1 
ATOM   2136 C  CA   . GLU A 1 291 ? 98.744  89.450  90.210  1.00 75.68  ? 291 GLU A CA   1 
ATOM   2137 C  C    . GLU A 1 291 ? 99.774  88.414  89.787  1.00 75.68  ? 291 GLU A C    1 
ATOM   2138 O  O    . GLU A 1 291 ? 99.428  87.471  89.068  1.00 75.68  ? 291 GLU A O    1 
ATOM   2139 C  CB   . GLU A 1 291 ? 98.312  90.300  89.018  1.00 75.68  ? 291 GLU A CB   1 
ATOM   2140 C  CG   . GLU A 1 291 ? 96.884  90.810  89.134  1.00 75.68  ? 291 GLU A CG   1 
ATOM   2141 C  CD   . GLU A 1 291 ? 96.721  91.822  90.260  1.00 75.68  ? 291 GLU A CD   1 
ATOM   2142 O  OE1  . GLU A 1 291 ? 97.694  92.537  90.575  1.00 75.68  ? 291 GLU A OE1  1 
ATOM   2143 O  OE2  . GLU A 1 291 ? 95.619  91.896  90.842  1.00 75.68  ? 291 GLU A OE2  1 
ATOM   2144 N  N    . LYS A 1 292 ? 101.023 88.560  90.226  1.00 73.59  ? 292 LYS A N    1 
ATOM   2145 C  CA   . LYS A 1 292 ? 102.047 87.555  90.005  1.00 73.59  ? 292 LYS A CA   1 
ATOM   2146 C  C    . LYS A 1 292 ? 102.457 86.804  91.262  1.00 73.59  ? 292 LYS A C    1 
ATOM   2147 O  O    . LYS A 1 292 ? 102.876 85.651  91.156  1.00 73.59  ? 292 LYS A O    1 
ATOM   2148 C  CB   . LYS A 1 292 ? 103.289 88.185  89.362  1.00 73.59  ? 292 LYS A CB   1 
ATOM   2149 C  CG   . LYS A 1 292 ? 102.955 89.111  88.202  1.00 73.59  ? 292 LYS A CG   1 
ATOM   2150 C  CD   . LYS A 1 292 ? 104.204 89.670  87.551  1.00 73.59  ? 292 LYS A CD   1 
ATOM   2151 C  CE   . LYS A 1 292 ? 104.780 90.813  88.354  1.00 73.59  ? 292 LYS A CE   1 
ATOM   2152 N  NZ   . LYS A 1 292 ? 104.144 92.095  87.951  1.00 73.59  ? 292 LYS A NZ   1 
ATOM   2153 N  N    . HIS A 1 293 ? 102.325 87.405  92.453  1.00 65.80  ? 293 HIS A N    1 
ATOM   2154 C  CA   . HIS A 1 293 ? 102.686 86.658  93.649  1.00 65.80  ? 293 HIS A CA   1 
ATOM   2155 C  C    . HIS A 1 293 ? 101.985 87.204  94.889  1.00 65.80  ? 293 HIS A C    1 
ATOM   2156 O  O    . HIS A 1 293 ? 102.576 87.995  95.630  1.00 65.80  ? 293 HIS A O    1 
ATOM   2157 C  CB   . HIS A 1 293 ? 104.200 86.685  93.858  1.00 65.80  ? 293 HIS A CB   1 
ATOM   2158 C  CG   . HIS A 1 293 ? 104.736 85.438  94.483  1.00 65.80  ? 293 HIS A CG   1 
ATOM   2159 N  ND1  . HIS A 1 293 ? 106.079 85.226  94.693  1.00 65.80  ? 293 HIS A ND1  1 
ATOM   2160 C  CD2  . HIS A 1 293 ? 104.107 84.323  94.928  1.00 65.80  ? 293 HIS A CD2  1 
ATOM   2161 C  CE1  . HIS A 1 293 ? 106.257 84.041  95.247  1.00 65.80  ? 293 HIS A CE1  1 
ATOM   2162 N  NE2  . HIS A 1 293 ? 105.076 83.472  95.401  1.00 65.80  ? 293 HIS A NE2  1 
ATOM   2163 N  N    . PRO A 1 294 ? 100.722 86.819  95.140  1.00 63.43  ? 294 PRO A N    1 
ATOM   2164 C  CA   . PRO A 1 294 ? 100.083 87.148  96.418  1.00 63.43  ? 294 PRO A CA   1 
ATOM   2165 C  C    . PRO A 1 294 ? 100.413 86.075  97.429  1.00 63.43  ? 294 PRO A C    1 
ATOM   2166 O  O    . PRO A 1 294 ? 101.258 85.219  97.155  1.00 63.43  ? 294 PRO A O    1 
ATOM   2167 C  CB   . PRO A 1 294 ? 98.596  87.150  96.075  1.00 63.43  ? 294 PRO A CB   1 
ATOM   2168 C  CG   . PRO A 1 294 ? 98.486  86.145  94.973  1.00 63.43  ? 294 PRO A CG   1 
ATOM   2169 C  CD   . PRO A 1 294 ? 99.845  85.982  94.313  1.00 63.43  ? 294 PRO A CD   1 
ATOM   2170 N  N    . CYS A 1 295 ? 99.789  86.121  98.603  1.00 57.83  ? 295 CYS A N    1 
ATOM   2171 C  CA   . CYS A 1 295 ? 99.928  85.154  99.689  1.00 57.83  ? 295 CYS A CA   1 
ATOM   2172 C  C    . CYS A 1 295 ? 101.311 85.156  100.316 1.00 57.83  ? 295 CYS A C    1 
ATOM   2173 O  O    . CYS A 1 295 ? 101.510 84.479  101.323 1.00 57.83  ? 295 CYS A O    1 
ATOM   2174 C  CB   . CYS A 1 295 ? 99.589  83.718  99.264  1.00 57.83  ? 295 CYS A CB   1 
ATOM   2175 S  SG   . CYS A 1 295 ? 97.901  83.497  98.692  1.00 57.83  ? 295 CYS A SG   1 
ATOM   2176 N  N    . LEU A 1 296 ? 102.274 85.879  99.757  1.00 50.69  ? 296 LEU A N    1 
ATOM   2177 C  CA   . LEU A 1 296 ? 103.464 86.282  100.485 1.00 50.69  ? 296 LEU A CA   1 
ATOM   2178 C  C    . LEU A 1 296 ? 103.288 87.661  101.083 1.00 50.69  ? 296 LEU A C    1 
ATOM   2179 O  O    . LEU A 1 296 ? 103.773 87.930  102.182 1.00 50.69  ? 296 LEU A O    1 
ATOM   2180 C  CB   . LEU A 1 296 ? 104.693 86.272  99.573  1.00 50.69  ? 296 LEU A CB   1 
ATOM   2181 C  CG   . LEU A 1 296 ? 105.524 84.991  99.489  1.00 50.69  ? 296 LEU A CG   1 
ATOM   2182 C  CD1  . LEU A 1 296 ? 106.130 84.696  100.838 1.00 50.69  ? 296 LEU A CD1  1 
ATOM   2183 C  CD2  . LEU A 1 296 ? 104.725 83.791  99.000  1.00 50.69  ? 296 LEU A CD2  1 
ATOM   2184 N  N    . TYR A 1 297 ? 102.570 88.525  100.376 1.00 44.16  ? 297 TYR A N    1 
ATOM   2185 C  CA   . TYR A 1 297 ? 102.246 89.843  100.901 1.00 44.16  ? 297 TYR A CA   1 
ATOM   2186 C  C    . TYR A 1 297 ? 101.328 89.733  102.112 1.00 44.16  ? 297 TYR A C    1 
ATOM   2187 O  O    . TYR A 1 297 ? 101.568 90.360  103.157 1.00 44.16  ? 297 TYR A O    1 
ATOM   2188 C  CB   . TYR A 1 297 ? 101.595 90.652  99.789  1.00 44.16  ? 297 TYR A CB   1 
ATOM   2189 C  CG   . TYR A 1 297 ? 101.252 92.064  100.128 1.00 44.16  ? 297 TYR A CG   1 
ATOM   2190 C  CD1  . TYR A 1 297 ? 100.023 92.387  100.653 1.00 44.16  ? 297 TYR A CD1  1 
ATOM   2191 C  CD2  . TYR A 1 297 ? 102.136 93.081  99.861  1.00 44.16  ? 297 TYR A CD2  1 
ATOM   2192 C  CE1  . TYR A 1 297 ? 99.701  93.669  100.935 1.00 44.16  ? 297 TYR A CE1  1 
ATOM   2193 C  CE2  . TYR A 1 297 ? 101.822 94.371  100.143 1.00 44.16  ? 297 TYR A CE2  1 
ATOM   2194 C  CZ   . TYR A 1 297 ? 100.600 94.658  100.671 1.00 44.16  ? 297 TYR A CZ   1 
ATOM   2195 O  OH   . TYR A 1 297 ? 100.269 95.951  100.969 1.00 44.16  ? 297 TYR A OH   1 
ATOM   2196 N  N    . ILE A 1 298 ? 100.261 88.939  101.989 1.00 47.15  ? 298 ILE A N    1 
ATOM   2197 C  CA   . ILE A 1 298 ? 99.350  88.771  103.113 1.00 47.15  ? 298 ILE A CA   1 
ATOM   2198 C  C    . ILE A 1 298 ? 100.036 88.035  104.250 1.00 47.15  ? 298 ILE A C    1 
ATOM   2199 O  O    . ILE A 1 298 ? 99.783  88.338  105.410 1.00 47.15  ? 298 ILE A O    1 
ATOM   2200 C  CB   . ILE A 1 298 ? 98.050  88.076  102.683 1.00 47.15  ? 298 ILE A CB   1 
ATOM   2201 C  CG1  . ILE A 1 298 ? 97.342  88.920  101.636 1.00 47.15  ? 298 ILE A CG1  1 
ATOM   2202 C  CG2  . ILE A 1 298 ? 97.117  87.919  103.848 1.00 47.15  ? 298 ILE A CG2  1 
ATOM   2203 C  CD1  . ILE A 1 298 ? 95.994  88.382  101.241 1.00 47.15  ? 298 ILE A CD1  1 
ATOM   2204 N  N    . LEU A 1 299 ? 100.938 87.096  103.963 1.00 43.35  ? 299 LEU A N    1 
ATOM   2205 C  CA   . LEU A 1 299 ? 101.679 86.473  105.056 1.00 43.35  ? 299 LEU A CA   1 
ATOM   2206 C  C    . LEU A 1 299 ? 102.645 87.440  105.730 1.00 43.35  ? 299 LEU A C    1 
ATOM   2207 O  O    . LEU A 1 299 ? 102.897 87.316  106.934 1.00 43.35  ? 299 LEU A O    1 
ATOM   2208 C  CB   . LEU A 1 299 ? 102.431 85.244  104.574 1.00 43.35  ? 299 LEU A CB   1 
ATOM   2209 C  CG   . LEU A 1 299 ? 101.578 83.985  104.547 1.00 43.35  ? 299 LEU A CG   1 
ATOM   2210 C  CD1  . LEU A 1 299 ? 102.404 82.799  104.102 1.00 43.35  ? 299 LEU A CD1  1 
ATOM   2211 C  CD2  . LEU A 1 299 ? 101.001 83.749  105.916 1.00 43.35  ? 299 LEU A CD2  1 
ATOM   2212 N  N    . MET A 1 300 ? 103.201 88.402  104.994 1.00 47.17  ? 300 MET A N    1 
ATOM   2213 C  CA   . MET A 1 300 ? 104.116 89.347  105.625 1.00 47.17  ? 300 MET A CA   1 
ATOM   2214 C  C    . MET A 1 300 ? 103.363 90.287  106.552 1.00 47.17  ? 300 MET A C    1 
ATOM   2215 O  O    . MET A 1 300 ? 103.736 90.460  107.725 1.00 47.17  ? 300 MET A O    1 
ATOM   2216 C  CB   . MET A 1 300 ? 104.894 90.115  104.563 1.00 47.17  ? 300 MET A CB   1 
ATOM   2217 C  CG   . MET A 1 300 ? 105.908 91.068  105.120 1.00 47.17  ? 300 MET A CG   1 
ATOM   2218 S  SD   . MET A 1 300 ? 105.945 92.573  104.162 1.00 47.17  ? 300 MET A SD   1 
ATOM   2219 C  CE   . MET A 1 300 ? 104.393 93.259  104.666 1.00 47.17  ? 300 MET A CE   1 
ATOM   2220 N  N    . PHE A 1 301 ? 102.261 90.860  106.068 1.00 45.30  ? 301 PHE A N    1 
ATOM   2221 C  CA   . PHE A 1 301 ? 101.401 91.545  107.025 1.00 45.30  ? 301 PHE A CA   1 
ATOM   2222 C  C    . PHE A 1 301 ? 100.786 90.598  108.039 1.00 45.30  ? 301 PHE A C    1 
ATOM   2223 O  O    . PHE A 1 301 ? 100.367 91.051  109.100 1.00 45.30  ? 301 PHE A O    1 
ATOM   2224 C  CB   . PHE A 1 301 ? 100.313 92.364  106.348 1.00 45.30  ? 301 PHE A CB   1 
ATOM   2225 C  CG   . PHE A 1 301 ? 100.816 93.611  105.710 1.00 45.30  ? 301 PHE A CG   1 
ATOM   2226 C  CD1  . PHE A 1 301 ? 101.072 94.717  106.489 1.00 45.30  ? 301 PHE A CD1  1 
ATOM   2227 C  CD2  . PHE A 1 301 ? 100.966 93.716  104.351 1.00 45.30  ? 301 PHE A CD2  1 
ATOM   2228 C  CE1  . PHE A 1 301 ? 101.524 95.882  105.932 1.00 45.30  ? 301 PHE A CE1  1 
ATOM   2229 C  CE2  . PHE A 1 301 ? 101.417 94.891  103.793 1.00 45.30  ? 301 PHE A CE2  1 
ATOM   2230 C  CZ   . PHE A 1 301 ? 101.692 95.970  104.583 1.00 45.30  ? 301 PHE A CZ   1 
ATOM   2231 N  N    . GLY A 1 302 ? 100.763 89.297  107.773 1.00 47.07  ? 302 GLY A N    1 
ATOM   2232 C  CA   . GLY A 1 302 ? 100.306 88.363  108.781 1.00 47.07  ? 302 GLY A CA   1 
ATOM   2233 C  C    . GLY A 1 302 ? 101.246 88.276  109.961 1.00 47.07  ? 302 GLY A C    1 
ATOM   2234 O  O    . GLY A 1 302 ? 100.811 88.310  111.109 1.00 47.07  ? 302 GLY A O    1 
ATOM   2235 N  N    . CYS A 1 303 ? 102.546 88.186  109.694 1.00 45.65  ? 303 CYS A N    1 
ATOM   2236 C  CA   . CYS A 1 303 ? 103.511 88.178  110.790 1.00 45.65  ? 303 CYS A CA   1 
ATOM   2237 C  C    . CYS A 1 303 ? 103.538 89.519  111.513 1.00 45.65  ? 303 CYS A C    1 
ATOM   2238 O  O    . CYS A 1 303 ? 103.630 89.567  112.750 1.00 45.65  ? 303 CYS A O    1 
ATOM   2239 C  CB   . CYS A 1 303 ? 104.896 87.803  110.278 1.00 45.65  ? 303 CYS A CB   1 
ATOM   2240 S  SG   . CYS A 1 303 ? 105.059 86.058  109.849 1.00 45.65  ? 303 CYS A SG   1 
ATOM   2241 N  N    . VAL A 1 304 ? 103.434 90.624  110.768 1.00 44.69  ? 304 VAL A N    1 
ATOM   2242 C  CA   . VAL A 1 304 ? 103.426 91.936  111.413 1.00 44.69  ? 304 VAL A CA   1 
ATOM   2243 C  C    . VAL A 1 304 ? 102.196 92.100  112.299 1.00 44.69  ? 304 VAL A C    1 
ATOM   2244 O  O    . VAL A 1 304 ? 102.293 92.511  113.465 1.00 44.69  ? 304 VAL A O    1 
ATOM   2245 C  CB   . VAL A 1 304 ? 103.512 93.044  110.356 1.00 44.69  ? 304 VAL A CB   1 
ATOM   2246 C  CG1  . VAL A 1 304 ? 103.189 94.375  110.966 1.00 44.69  ? 304 VAL A CG1  1 
ATOM   2247 C  CG2  . VAL A 1 304 ? 104.885 93.054  109.785 1.00 44.69  ? 304 VAL A CG2  1 
ATOM   2248 N  N    . PHE A 1 305 ? 101.024 91.761  111.768 1.00 47.14  ? 305 PHE A N    1 
ATOM   2249 C  CA   . PHE A 1 305 ? 99.802  91.833  112.552 1.00 47.14  ? 305 PHE A CA   1 
ATOM   2250 C  C    . PHE A 1 305 ? 99.821  90.838  113.696 1.00 47.14  ? 305 PHE A C    1 
ATOM   2251 O  O    . PHE A 1 305 ? 99.222  91.095  114.743 1.00 47.14  ? 305 PHE A O    1 
ATOM   2252 C  CB   . PHE A 1 305 ? 98.604  91.602  111.640 1.00 47.14  ? 305 PHE A CB   1 
ATOM   2253 C  CG   . PHE A 1 305 ? 97.382  91.145  112.351 1.00 47.14  ? 305 PHE A CG   1 
ATOM   2254 C  CD1  . PHE A 1 305 ? 96.605  92.041  113.038 1.00 47.14  ? 305 PHE A CD1  1 
ATOM   2255 C  CD2  . PHE A 1 305 ? 97.003  89.821  112.321 1.00 47.14  ? 305 PHE A CD2  1 
ATOM   2256 C  CE1  . PHE A 1 305 ? 95.483  91.626  113.687 1.00 47.14  ? 305 PHE A CE1  1 
ATOM   2257 C  CE2  . PHE A 1 305 ? 95.882  89.404  112.971 1.00 47.14  ? 305 PHE A CE2  1 
ATOM   2258 C  CZ   . PHE A 1 305 ? 95.120  90.305  113.655 1.00 47.14  ? 305 PHE A CZ   1 
ATOM   2259 N  N    . ALA A 1 306 ? 100.514 89.713  113.532 1.00 50.56  ? 306 ALA A N    1 
ATOM   2260 C  CA   . ALA A 1 306 ? 100.638 88.759  114.621 1.00 50.56  ? 306 ALA A CA   1 
ATOM   2261 C  C    . ALA A 1 306 ? 101.398 89.362  115.790 1.00 50.56  ? 306 ALA A C    1 
ATOM   2262 O  O    . ALA A 1 306 ? 100.963 89.247  116.939 1.00 50.56  ? 306 ALA A O    1 
ATOM   2263 C  CB   . ALA A 1 306 ? 101.325 87.489  114.133 1.00 50.56  ? 306 ALA A CB   1 
ATOM   2264 N  N    . LYS A 1 307 ? 102.523 90.030  115.519 1.00 53.58  ? 307 LYS A N    1 
ATOM   2265 C  CA   . LYS A 1 307 ? 103.234 90.663  116.627 1.00 53.58  ? 307 LYS A CA   1 
ATOM   2266 C  C    . LYS A 1 307 ? 102.415 91.791  117.243 1.00 53.58  ? 307 LYS A C    1 
ATOM   2267 O  O    . LYS A 1 307 ? 102.383 91.934  118.470 1.00 53.58  ? 307 LYS A O    1 
ATOM   2268 C  CB   . LYS A 1 307 ? 104.605 91.184  116.210 1.00 53.58  ? 307 LYS A CB   1 
ATOM   2269 C  CG   . LYS A 1 307 ? 105.284 91.891  117.377 1.00 53.58  ? 307 LYS A CG   1 
ATOM   2270 C  CD   . LYS A 1 307 ? 106.701 92.294  117.116 1.00 53.58  ? 307 LYS A CD   1 
ATOM   2271 C  CE   . LYS A 1 307 ? 107.226 93.230  118.189 1.00 53.58  ? 307 LYS A CE   1 
ATOM   2272 N  NZ   . LYS A 1 307 ? 107.311 92.584  119.518 1.00 53.58  ? 307 LYS A NZ   1 
ATOM   2273 N  N    . VAL A 1 308 ? 101.737 92.592  116.421 1.00 50.03  ? 308 VAL A N    1 
ATOM   2274 C  CA   . VAL A 1 308 ? 100.963 93.701  116.979 1.00 50.03  ? 308 VAL A CA   1 
ATOM   2275 C  C    . VAL A 1 308 ? 99.829  93.185  117.863 1.00 50.03  ? 308 VAL A C    1 
ATOM   2276 O  O    . VAL A 1 308 ? 99.601  93.695  118.971 1.00 50.03  ? 308 VAL A O    1 
ATOM   2277 C  CB   . VAL A 1 308 ? 100.446 94.606  115.850 1.00 50.03  ? 308 VAL A CB   1 
ATOM   2278 C  CG1  . VAL A 1 308 ? 99.378  95.510  116.371 1.00 50.03  ? 308 VAL A CG1  1 
ATOM   2279 C  CG2  . VAL A 1 308 ? 101.581 95.422  115.291 1.00 50.03  ? 308 VAL A CG2  1 
ATOM   2280 N  N    . SER A 1 309 ? 99.128  92.145  117.414 1.00 53.90  ? 309 SER A N    1 
ATOM   2281 C  CA   . SER A 1 309 ? 98.063  91.584  118.232 1.00 53.90  ? 309 SER A CA   1 
ATOM   2282 C  C    . SER A 1 309 ? 98.606  90.902  119.478 1.00 53.90  ? 309 SER A C    1 
ATOM   2283 O  O    . SER A 1 309 ? 97.967  90.961  120.529 1.00 53.90  ? 309 SER A O    1 
ATOM   2284 C  CB   . SER A 1 309 ? 97.232  90.597  117.427 1.00 53.90  ? 309 SER A CB   1 
ATOM   2285 O  OG   . SER A 1 309 ? 97.973  89.418  117.197 1.00 53.90  ? 309 SER A OG   1 
ATOM   2286 N  N    . GLN A 1 310 ? 99.775  90.260  119.395 1.00 58.98  ? 310 GLN A N    1 
ATOM   2287 C  CA   . GLN A 1 310 ? 100.386 89.694  120.595 1.00 58.98  ? 310 GLN A CA   1 
ATOM   2288 C  C    . GLN A 1 310 ? 100.715 90.787  121.605 1.00 58.98  ? 310 GLN A C    1 
ATOM   2289 O  O    . GLN A 1 310 ? 100.543 90.600  122.817 1.00 58.98  ? 310 GLN A O    1 
ATOM   2290 C  CB   . GLN A 1 310 ? 101.647 88.917  120.230 1.00 58.98  ? 310 GLN A CB   1 
ATOM   2291 C  CG   . GLN A 1 310 ? 101.418 87.478  119.830 1.00 58.98  ? 310 GLN A CG   1 
ATOM   2292 C  CD   . GLN A 1 310 ? 102.672 86.835  119.274 1.00 58.98  ? 310 GLN A CD   1 
ATOM   2293 O  OE1  . GLN A 1 310 ? 103.717 87.468  119.185 1.00 58.98  ? 310 GLN A OE1  1 
ATOM   2294 N  NE2  . GLN A 1 310 ? 102.574 85.567  118.899 1.00 58.98  ? 310 GLN A NE2  1 
ATOM   2295 N  N    . LYS A 1 311 ? 101.193 91.931  121.119 1.00 58.28  ? 311 LYS A N    1 
ATOM   2296 C  CA   . LYS A 1 311 ? 101.469 93.052  122.008 1.00 58.28  ? 311 LYS A CA   1 
ATOM   2297 C  C    . LYS A 1 311 ? 100.198 93.542  122.676 1.00 58.28  ? 311 LYS A C    1 
ATOM   2298 O  O    . LYS A 1 311 ? 100.204 93.865  123.868 1.00 58.28  ? 311 LYS A O    1 
ATOM   2299 C  CB   . LYS A 1 311 ? 102.142 94.179  121.239 1.00 58.28  ? 311 LYS A CB   1 
ATOM   2300 C  CG   . LYS A 1 311 ? 103.624 94.289  121.499 1.00 58.28  ? 311 LYS A CG   1 
ATOM   2301 C  CD   . LYS A 1 311 ? 104.201 95.458  120.754 1.00 58.28  ? 311 LYS A CD   1 
ATOM   2302 C  CE   . LYS A 1 311 ? 103.572 96.741  121.219 1.00 58.28  ? 311 LYS A CE   1 
ATOM   2303 N  NZ   . LYS A 1 311 ? 103.940 97.861  120.329 1.00 58.28  ? 311 LYS A NZ   1 
ATOM   2304 N  N    . LEU A 1 312 ? 99.092  93.599  121.937 1.00 55.32  ? 312 LEU A N    1 
ATOM   2305 C  CA   . LEU A 1 312 ? 97.849  94.010  122.586 1.00 55.32  ? 312 LEU A CA   1 
ATOM   2306 C  C    . LEU A 1 312 ? 97.353  92.951  123.566 1.00 55.32  ? 312 LEU A C    1 
ATOM   2307 O  O    . LEU A 1 312 ? 96.719  93.293  124.571 1.00 55.32  ? 312 LEU A O    1 
ATOM   2308 C  CB   . LEU A 1 312 ? 96.774  94.332  121.555 1.00 55.32  ? 312 LEU A CB   1 
ATOM   2309 C  CG   . LEU A 1 312 ? 95.556  95.069  122.111 1.00 55.32  ? 312 LEU A CG   1 
ATOM   2310 C  CD1  . LEU A 1 312 ? 95.078  96.067  121.108 1.00 55.32  ? 312 LEU A CD1  1 
ATOM   2311 C  CD2  . LEU A 1 312 ? 94.422  94.142  122.435 1.00 55.32  ? 312 LEU A CD2  1 
ATOM   2312 N  N    . VAL A 1 313 ? 97.628  91.673  123.298 1.00 63.20  ? 313 VAL A N    1 
ATOM   2313 C  CA   . VAL A 1 313 ? 97.294  90.626  124.264 1.00 63.20  ? 313 VAL A CA   1 
ATOM   2314 C  C    . VAL A 1 313 ? 98.033  90.862  125.572 1.00 63.20  ? 313 VAL A C    1 
ATOM   2315 O  O    . VAL A 1 313 ? 97.431  90.875  126.657 1.00 63.20  ? 313 VAL A O    1 
ATOM   2316 C  CB   . VAL A 1 313 ? 97.599  89.233  123.692 1.00 63.20  ? 313 VAL A CB   1 
ATOM   2317 C  CG1  . VAL A 1 313 ? 97.406  88.195  124.760 1.00 63.20  ? 313 VAL A CG1  1 
ATOM   2318 C  CG2  . VAL A 1 313 ? 96.661  88.926  122.557 1.00 63.20  ? 313 VAL A CG2  1 
ATOM   2319 N  N    . VAL A 1 314 ? 99.344  91.091  125.479 1.00 66.48  ? 314 VAL A N    1 
ATOM   2320 C  CA   . VAL A 1 314 ? 100.147 91.391  126.659 1.00 66.48  ? 314 VAL A CA   1 
ATOM   2321 C  C    . VAL A 1 314 ? 99.627  92.645  127.345 1.00 66.48  ? 314 VAL A C    1 
ATOM   2322 O  O    . VAL A 1 314 ? 99.575  92.722  128.576 1.00 66.48  ? 314 VAL A O    1 
ATOM   2323 C  CB   . VAL A 1 314 ? 101.626 91.524  126.270 1.00 66.48  ? 314 VAL A CB   1 
ATOM   2324 C  CG1  . VAL A 1 314 ? 102.440 92.019  127.430 1.00 66.48  ? 314 VAL A CG1  1 
ATOM   2325 C  CG2  . VAL A 1 314 ? 102.146 90.195  125.807 1.00 66.48  ? 314 VAL A CG2  1 
ATOM   2326 N  N    . ALA A 1 315 ? 99.186  93.625  126.562 1.00 70.47  ? 315 ALA A N    1 
ATOM   2327 C  CA   . ALA A 1 315 ? 98.686  94.858  127.148 1.00 70.47  ? 315 ALA A CA   1 
ATOM   2328 C  C    . ALA A 1 315 ? 97.375  94.662  127.898 1.00 70.47  ? 315 ALA A C    1 
ATOM   2329 O  O    . ALA A 1 315 ? 97.147  95.339  128.901 1.00 70.47  ? 315 ALA A O    1 
ATOM   2330 C  CB   . ALA A 1 315 ? 98.515  95.921  126.069 1.00 70.47  ? 315 ALA A CB   1 
ATOM   2331 N  N    . HIS A 1 316 ? 96.489  93.770  127.448 1.00 72.30  ? 316 HIS A N    1 
ATOM   2332 C  CA   . HIS A 1 316 ? 95.243  93.713  128.204 1.00 72.30  ? 316 HIS A CA   1 
ATOM   2333 C  C    . HIS A 1 316 ? 95.307  92.716  129.344 1.00 72.30  ? 316 HIS A C    1 
ATOM   2334 O  O    . HIS A 1 316 ? 94.575  92.874  130.325 1.00 72.30  ? 316 HIS A O    1 
ATOM   2335 C  CB   . HIS A 1 316 ? 94.013  93.362  127.364 1.00 72.30  ? 316 HIS A CB   1 
ATOM   2336 C  CG   . HIS A 1 316 ? 94.039  92.001  126.750 1.00 72.30  ? 316 HIS A CG   1 
ATOM   2337 N  ND1  . HIS A 1 316 ? 93.598  90.883  127.426 1.00 72.30  ? 316 HIS A ND1  1 
ATOM   2338 C  CD2  . HIS A 1 316 ? 94.340  91.588  125.499 1.00 72.30  ? 316 HIS A CD2  1 
ATOM   2339 C  CE1  . HIS A 1 316 ? 93.687  89.829  126.636 1.00 72.30  ? 316 HIS A CE1  1 
ATOM   2340 N  NE2  . HIS A 1 316 ? 94.138  90.230  125.461 1.00 72.30  ? 316 HIS A NE2  1 
ATOM   2341 N  N    . MET A 1 317 ? 96.135  91.675  129.256 1.00 83.95  ? 317 MET A N    1 
ATOM   2342 C  CA   . MET A 1 317 ? 96.227  90.860  130.457 1.00 83.95  ? 317 MET A CA   1 
ATOM   2343 C  C    . MET A 1 317 ? 97.346  91.300  131.386 1.00 83.95  ? 317 MET A C    1 
ATOM   2344 O  O    . MET A 1 317 ? 97.491  90.727  132.468 1.00 83.95  ? 317 MET A O    1 
ATOM   2345 C  CB   . MET A 1 317 ? 96.389  89.381  130.124 1.00 83.95  ? 317 MET A CB   1 
ATOM   2346 C  CG   . MET A 1 317 ? 97.488  89.028  129.179 1.00 83.95  ? 317 MET A CG   1 
ATOM   2347 S  SD   . MET A 1 317 ? 97.946  87.326  129.495 1.00 83.95  ? 317 MET A SD   1 
ATOM   2348 C  CE   . MET A 1 317 ? 96.739  86.522  128.458 1.00 83.95  ? 317 MET A CE   1 
ATOM   2349 N  N    . THR A 1 318 ? 98.137  92.298  130.998 1.00 84.03  ? 318 THR A N    1 
ATOM   2350 C  CA   . THR A 1 318 ? 99.080  92.938  131.902 1.00 84.03  ? 318 THR A CA   1 
ATOM   2351 C  C    . THR A 1 318 ? 98.929  94.435  131.710 1.00 84.03  ? 318 THR A C    1 
ATOM   2352 O  O    . THR A 1 318 ? 99.303  94.958  130.655 1.00 84.03  ? 318 THR A O    1 
ATOM   2353 C  CB   . THR A 1 318 ? 100.518 92.496  131.626 1.00 84.03  ? 318 THR A CB   1 
ATOM   2354 O  OG1  . THR A 1 318 ? 100.669 91.119  131.979 1.00 84.03  ? 318 THR A OG1  1 
ATOM   2355 C  CG2  . THR A 1 318 ? 101.483 93.319  132.433 1.00 84.03  ? 318 THR A CG2  1 
ATOM   2356 N  N    . LYS A 1 319 ? 98.394  95.118  132.719 1.00 86.78  ? 319 LYS A N    1 
ATOM   2357 C  CA   . LYS A 1 319 ? 97.917  96.484  132.554 1.00 86.78  ? 319 LYS A CA   1 
ATOM   2358 C  C    . LYS A 1 319 ? 99.050  97.424  132.179 1.00 86.78  ? 319 LYS A C    1 
ATOM   2359 O  O    . LYS A 1 319 ? 99.896  97.758  133.014 1.00 86.78  ? 319 LYS A O    1 
ATOM   2360 C  CB   . LYS A 1 319 ? 97.238  96.967  133.835 1.00 86.78  ? 319 LYS A CB   1 
ATOM   2361 C  CG   . LYS A 1 319 ? 95.773  96.597  133.945 1.00 86.78  ? 319 LYS A CG   1 
ATOM   2362 C  CD   . LYS A 1 319 ? 95.594  95.183  134.469 1.00 86.78  ? 319 LYS A CD   1 
ATOM   2363 C  CE   . LYS A 1 319 ? 94.288  95.040  135.227 1.00 86.78  ? 319 LYS A CE   1 
ATOM   2364 N  NZ   . LYS A 1 319 ? 94.231  93.771  136.000 1.00 86.78  ? 319 LYS A NZ   1 
ATOM   2365 N  N    . SER A 1 320 ? 99.077  97.847  130.919 1.00 76.25  ? 320 SER A N    1 
ATOM   2366 C  CA   . SER A 1 320 ? 100.165 98.663  130.407 1.00 76.25  ? 320 SER A CA   1 
ATOM   2367 C  C    . SER A 1 320 ? 99.659  99.444  129.208 1.00 76.25  ? 320 SER A C    1 
ATOM   2368 O  O    . SER A 1 320 ? 98.618  99.124  128.630 1.00 76.25  ? 320 SER A O    1 
ATOM   2369 C  CB   . SER A 1 320 ? 101.373 97.809  130.016 1.00 76.25  ? 320 SER A CB   1 
ATOM   2370 O  OG   . SER A 1 320 ? 101.904 97.120  131.134 1.00 76.25  ? 320 SER A OG   1 
ATOM   2371 N  N    . GLU A 1 321 ? 100.410 100.474 128.841 1.00 70.35  ? 321 GLU A N    1 
ATOM   2372 C  CA   . GLU A 1 321 ? 100.068 101.297 127.692 1.00 70.35  ? 321 GLU A CA   1 
ATOM   2373 C  C    . GLU A 1 321 ? 100.597 100.645 126.423 1.00 70.35  ? 321 GLU A C    1 
ATOM   2374 O  O    . GLU A 1 321 ? 101.628 99.968  126.442 1.00 70.35  ? 321 GLU A O    1 
ATOM   2375 C  CB   . GLU A 1 321 ? 100.649 102.705 127.847 1.00 70.35  ? 321 GLU A CB   1 
ATOM   2376 C  CG   . GLU A 1 321 ? 100.051 103.747 126.908 1.00 70.35  ? 321 GLU A CG   1 
ATOM   2377 C  CD   . GLU A 1 321 ? 100.691 105.115 127.055 1.00 70.35  ? 321 GLU A CD   1 
ATOM   2378 O  OE1  . GLU A 1 321 ? 101.272 105.386 128.128 1.00 70.35  ? 321 GLU A OE1  1 
ATOM   2379 O  OE2  . GLU A 1 321 ? 100.610 105.919 126.102 1.00 70.35  ? 321 GLU A OE2  1 
ATOM   2380 N  N    . LEU A 1 322 ? 99.874  100.839 125.323 1.00 66.90  ? 322 LEU A N    1 
ATOM   2381 C  CA   . LEU A 1 322 ? 100.350 100.365 124.033 1.00 66.90  ? 322 LEU A CA   1 
ATOM   2382 C  C    . LEU A 1 322 ? 101.473 101.254 123.523 1.00 66.90  ? 322 LEU A C    1 
ATOM   2383 O  O    . LEU A 1 322 ? 101.554 102.442 123.844 1.00 66.90  ? 322 LEU A O    1 
ATOM   2384 C  CB   . LEU A 1 322 ? 99.223  100.337 123.005 1.00 66.90  ? 322 LEU A CB   1 
ATOM   2385 C  CG   . LEU A 1 322 ? 98.294  99.128  122.939 1.00 66.90  ? 322 LEU A CG   1 
ATOM   2386 C  CD1  . LEU A 1 322 ? 99.076  97.878  122.572 1.00 66.90  ? 322 LEU A CD1  1 
ATOM   2387 C  CD2  . LEU A 1 322 ? 97.516  98.930  124.213 1.00 66.90  ? 322 LEU A CD2  1 
ATOM   2388 N  N    . TYR A 1 323 ? 102.350 100.666 122.720 1.00 64.09  ? 323 TYR A N    1 
ATOM   2389 C  CA   . TYR A 1 323 ? 103.475 101.379 122.138 1.00 64.09  ? 323 TYR A CA   1 
ATOM   2390 C  C    . TYR A 1 323 ? 103.442 101.202 120.628 1.00 64.09  ? 323 TYR A C    1 
ATOM   2391 O  O    . TYR A 1 323 ? 103.295 100.082 120.134 1.00 64.09  ? 323 TYR A O    1 
ATOM   2392 C  CB   . TYR A 1 323 ? 104.803 100.877 122.709 1.00 64.09  ? 323 TYR A CB   1 
ATOM   2393 C  CG   . TYR A 1 323 ? 105.122 101.392 124.100 1.00 64.09  ? 323 TYR A CG   1 
ATOM   2394 C  CD1  . TYR A 1 323 ? 104.350 101.027 125.193 1.00 64.09  ? 323 TYR A CD1  1 
ATOM   2395 C  CD2  . TYR A 1 323 ? 106.209 102.225 124.319 1.00 64.09  ? 323 TYR A CD2  1 
ATOM   2396 C  CE1  . TYR A 1 323 ? 104.640 101.492 126.460 1.00 64.09  ? 323 TYR A CE1  1 
ATOM   2397 C  CE2  . TYR A 1 323 ? 106.504 102.696 125.586 1.00 64.09  ? 323 TYR A CE2  1 
ATOM   2398 C  CZ   . TYR A 1 323 ? 105.716 102.323 126.650 1.00 64.09  ? 323 TYR A CZ   1 
ATOM   2399 O  OH   . TYR A 1 323 ? 106.004 102.783 127.912 1.00 64.09  ? 323 TYR A OH   1 
ATOM   2400 N  N    . LEU A 1 324 ? 103.558 102.311 119.897 1.00 63.48  ? 324 LEU A N    1 
ATOM   2401 C  CA   . LEU A 1 324 ? 103.649 102.235 118.444 1.00 63.48  ? 324 LEU A CA   1 
ATOM   2402 C  C    . LEU A 1 324 ? 105.018 101.772 117.974 1.00 63.48  ? 324 LEU A C    1 
ATOM   2403 O  O    . LEU A 1 324 ? 105.115 101.116 116.931 1.00 63.48  ? 324 LEU A O    1 
ATOM   2404 C  CB   . LEU A 1 324 ? 103.326 103.590 117.819 1.00 63.48  ? 324 LEU A CB   1 
ATOM   2405 C  CG   . LEU A 1 324 ? 101.891 103.912 117.400 1.00 63.48  ? 324 LEU A CG   1 
ATOM   2406 C  CD1  . LEU A 1 324 ? 101.503 103.048 116.224 1.00 63.48  ? 324 LEU A CD1  1 
ATOM   2407 C  CD2  . LEU A 1 324 ? 100.914 103.722 118.547 1.00 63.48  ? 324 LEU A CD2  1 
ATOM   2408 N  N    . GLN A 1 325 ? 106.077 102.103 118.707 1.00 65.65  ? 325 GLN A N    1 
ATOM   2409 C  CA   . GLN A 1 325 ? 107.430 101.775 118.280 1.00 65.65  ? 325 GLN A CA   1 
ATOM   2410 C  C    . GLN A 1 325 ? 107.624 100.268 118.329 1.00 65.65  ? 325 GLN A C    1 
ATOM   2411 O  O    . GLN A 1 325 ? 107.651 99.672  119.410 1.00 65.65  ? 325 GLN A O    1 
ATOM   2412 C  CB   . GLN A 1 325 ? 108.460 102.474 119.159 1.00 65.65  ? 325 GLN A CB   1 
ATOM   2413 C  CG   . GLN A 1 325 ? 109.902 102.226 118.730 1.00 65.65  ? 325 GLN A CG   1 
ATOM   2414 C  CD   . GLN A 1 325 ? 110.621 101.210 119.601 1.00 65.65  ? 325 GLN A CD   1 
ATOM   2415 O  OE1  . GLN A 1 325 ? 110.152 100.855 120.681 1.00 65.65  ? 325 GLN A OE1  1 
ATOM   2416 N  NE2  . GLN A 1 325 ? 111.766 100.734 119.128 1.00 65.65  ? 325 GLN A NE2  1 
ATOM   2417 N  N    . ASP A 1 326 ? 107.758 99.647  117.164 1.00 65.34  ? 326 ASP A N    1 
ATOM   2418 C  CA   . ASP A 1 326 ? 108.023 98.222  117.083 1.00 65.34  ? 326 ASP A CA   1 
ATOM   2419 C  C    . ASP A 1 326 ? 109.020 97.965  115.971 1.00 65.34  ? 326 ASP A C    1 
ATOM   2420 O  O    . ASP A 1 326 ? 109.078 98.706  114.988 1.00 65.34  ? 326 ASP A O    1 
ATOM   2421 C  CB   . ASP A 1 326 ? 106.743 97.427  116.845 1.00 65.34  ? 326 ASP A CB   1 
ATOM   2422 C  CG   . ASP A 1 326 ? 106.005 97.128  118.124 1.00 65.34  ? 326 ASP A CG   1 
ATOM   2423 O  OD1  . ASP A 1 326 ? 106.659 96.705  119.099 1.00 65.34  ? 326 ASP A OD1  1 
ATOM   2424 O  OD2  . ASP A 1 326 ? 104.774 97.319  118.165 1.00 65.34  ? 326 ASP A OD2  1 
ATOM   2425 N  N    . THR A 1 327 ? 109.811 96.909  116.136 1.00 58.19  ? 327 THR A N    1 
ATOM   2426 C  CA   . THR A 1 327 ? 110.829 96.605  115.141 1.00 58.19  ? 327 THR A CA   1 
ATOM   2427 C  C    . THR A 1 327 ? 110.242 95.969  113.886 1.00 58.19  ? 327 THR A C    1 
ATOM   2428 O  O    . THR A 1 327 ? 110.810 96.129  112.801 1.00 58.19  ? 327 THR A O    1 
ATOM   2429 C  CB   . THR A 1 327 ? 111.907 95.706  115.750 1.00 58.19  ? 327 THR A CB   1 
ATOM   2430 O  OG1  . THR A 1 327 ? 112.956 95.504  114.795 1.00 58.19  ? 327 THR A OG1  1 
ATOM   2431 C  CG2  . THR A 1 327 ? 111.336 94.368  116.175 1.00 58.19  ? 327 THR A CG2  1 
ATOM   2432 N  N    . VAL A 1 328 ? 109.105 95.279  113.997 1.00 57.72  ? 328 VAL A N    1 
ATOM   2433 C  CA   . VAL A 1 328 ? 108.566 94.579  112.837 1.00 57.72  ? 328 VAL A CA   1 
ATOM   2434 C  C    . VAL A 1 328 ? 107.958 95.519  111.826 1.00 57.72  ? 328 VAL A C    1 
ATOM   2435 O  O    . VAL A 1 328 ? 107.708 95.111  110.691 1.00 57.72  ? 328 VAL A O    1 
ATOM   2436 C  CB   . VAL A 1 328 ? 107.525 93.534  113.240 1.00 57.72  ? 328 VAL A CB   1 
ATOM   2437 C  CG1  . VAL A 1 328 ? 108.201 92.423  113.983 1.00 57.72  ? 328 VAL A CG1  1 
ATOM   2438 C  CG2  . VAL A 1 328 ? 106.443 94.188  114.064 1.00 57.72  ? 328 VAL A CG2  1 
ATOM   2439 N  N    . PHE A 1 329 ? 107.722 96.775  112.188 1.00 54.91  ? 329 PHE A N    1 
ATOM   2440 C  CA   . PHE A 1 329 ? 107.329 97.717  111.154 1.00 54.91  ? 329 PHE A CA   1 
ATOM   2441 C  C    . PHE A 1 329 ? 108.475 98.030  110.209 1.00 54.91  ? 329 PHE A C    1 
ATOM   2442 O  O    . PHE A 1 329 ? 108.255 98.706  109.202 1.00 54.91  ? 329 PHE A O    1 
ATOM   2443 C  CB   . PHE A 1 329 ? 106.779 98.988  111.783 1.00 54.91  ? 329 PHE A CB   1 
ATOM   2444 C  CG   . PHE A 1 329 ? 105.339 98.883  112.153 1.00 54.91  ? 329 PHE A CG   1 
ATOM   2445 C  CD1  . PHE A 1 329 ? 104.405 98.517  111.214 1.00 54.91  ? 329 PHE A CD1  1 
ATOM   2446 C  CD2  . PHE A 1 329 ? 104.919 99.140  113.442 1.00 54.91  ? 329 PHE A CD2  1 
ATOM   2447 C  CE1  . PHE A 1 329 ? 103.082 98.411  111.549 1.00 54.91  ? 329 PHE A CE1  1 
ATOM   2448 C  CE2  . PHE A 1 329 ? 103.591 99.038  113.777 1.00 54.91  ? 329 PHE A CE2  1 
ATOM   2449 C  CZ   . PHE A 1 329 ? 102.676 98.676  112.832 1.00 54.91  ? 329 PHE A CZ   1 
ATOM   2450 N  N    . LEU A 1 330 ? 109.685 97.555  110.505 1.00 56.56  ? 330 LEU A N    1 
ATOM   2451 C  CA   . LEU A 1 330 ? 110.748 97.558  109.511 1.00 56.56  ? 330 LEU A CA   1 
ATOM   2452 C  C    . LEU A 1 330 ? 110.433 96.649  108.332 1.00 56.56  ? 330 LEU A C    1 
ATOM   2453 O  O    . LEU A 1 330 ? 111.018 96.823  107.259 1.00 56.56  ? 330 LEU A O    1 
ATOM   2454 C  CB   . LEU A 1 330 ? 112.063 97.122  110.150 1.00 56.56  ? 330 LEU A CB   1 
ATOM   2455 C  CG   . LEU A 1 330 ? 113.311 97.781  109.581 1.00 56.56  ? 330 LEU A CG   1 
ATOM   2456 C  CD1  . LEU A 1 330 ? 113.268 99.276  109.837 1.00 56.56  ? 330 LEU A CD1  1 
ATOM   2457 C  CD2  . LEU A 1 330 ? 114.548 97.161  110.194 1.00 56.56  ? 330 LEU A CD2  1 
ATOM   2458 N  N    . GLY A 1 331 ? 109.533 95.685  108.505 1.00 50.39  ? 331 GLY A N    1 
ATOM   2459 C  CA   . GLY A 1 331 ? 109.187 94.766  107.448 1.00 50.39  ? 331 GLY A CA   1 
ATOM   2460 C  C    . GLY A 1 331 ? 108.423 95.414  106.314 1.00 50.39  ? 331 GLY A C    1 
ATOM   2461 O  O    . GLY A 1 331 ? 108.940 95.566  105.206 1.00 50.39  ? 331 GLY A O    1 
ATOM   2462 N  N    . PRO A 1 332 ? 107.166 95.792  106.560 1.00 49.64  ? 332 PRO A N    1 
ATOM   2463 C  CA   . PRO A 1 332 ? 106.413 96.514  105.527 1.00 49.64  ? 332 PRO A CA   1 
ATOM   2464 C  C    . PRO A 1 332 ? 107.045 97.834  105.160 1.00 49.64  ? 332 PRO A C    1 
ATOM   2465 O  O    . PRO A 1 332 ? 107.042 98.214  103.982 1.00 49.64  ? 332 PRO A O    1 
ATOM   2466 C  CB   . PRO A 1 332 ? 105.037 96.721  106.171 1.00 49.64  ? 332 PRO A CB   1 
ATOM   2467 C  CG   . PRO A 1 332 ? 104.974 95.747  107.259 1.00 49.64  ? 332 PRO A CG   1 
ATOM   2468 C  CD   . PRO A 1 332 ? 106.359 95.589  107.766 1.00 49.64  ? 332 PRO A CD   1 
ATOM   2469 N  N    . GLY A 1 333 ? 107.617 98.530  106.142 1.00 51.09  ? 333 GLY A N    1 
ATOM   2470 C  CA   . GLY A 1 333 ? 108.207 99.827  105.878 1.00 51.09  ? 333 GLY A CA   1 
ATOM   2471 C  C    . GLY A 1 333 ? 109.301 99.764  104.838 1.00 51.09  ? 333 GLY A C    1 
ATOM   2472 O  O    . GLY A 1 333 ? 109.417 100.670 104.007 1.00 51.09  ? 333 GLY A O    1 
ATOM   2473 N  N    . LEU A 1 334 ? 110.080 98.678  104.839 1.00 50.53  ? 334 LEU A N    1 
ATOM   2474 C  CA   . LEU A 1 334 ? 111.087 98.470  103.807 1.00 50.53  ? 334 LEU A CA   1 
ATOM   2475 C  C    . LEU A 1 334 ? 110.463 98.535  102.422 1.00 50.53  ? 334 LEU A C    1 
ATOM   2476 O  O    . LEU A 1 334 ? 110.935 99.287  101.557 1.00 50.53  ? 334 LEU A O    1 
ATOM   2477 C  CB   . LEU A 1 334 ? 111.784 97.130  104.019 1.00 50.53  ? 334 LEU A CB   1 
ATOM   2478 C  CG   . LEU A 1 334 ? 113.243 97.114  103.588 1.00 50.53  ? 334 LEU A CG   1 
ATOM   2479 C  CD1  . LEU A 1 334 ? 114.041 97.997  104.516 1.00 50.53  ? 334 LEU A CD1  1 
ATOM   2480 C  CD2  . LEU A 1 334 ? 113.792 95.706  103.585 1.00 50.53  ? 334 LEU A CD2  1 
ATOM   2481 N  N    . LEU A 1 335 ? 109.360 97.802  102.215 1.00 48.36  ? 335 LEU A N    1 
ATOM   2482 C  CA   . LEU A 1 335 ? 108.621 97.890  100.959 1.00 48.36  ? 335 LEU A CA   1 
ATOM   2483 C  C    . LEU A 1 335 ? 108.278 99.330  100.642 1.00 48.36  ? 335 LEU A C    1 
ATOM   2484 O  O    . LEU A 1 335 ? 108.535 99.810  99.530  1.00 48.36  ? 335 LEU A O    1 
ATOM   2485 C  CB   . LEU A 1 335 ? 107.341 97.060  101.018 1.00 48.36  ? 335 LEU A CB   1 
ATOM   2486 C  CG   . LEU A 1 335 ? 107.420 95.545  100.919 1.00 48.36  ? 335 LEU A CG   1 
ATOM   2487 C  CD1  . LEU A 1 335 ? 106.057 94.958  101.169 1.00 48.36  ? 335 LEU A CD1  1 
ATOM   2488 C  CD2  . LEU A 1 335 ? 107.890 95.166  99.552  1.00 48.36  ? 335 LEU A CD2  1 
ATOM   2489 N  N    . PHE A 1 336 ? 107.766 100.051 101.644 1.00 48.17  ? 336 PHE A N    1 
ATOM   2490 C  CA   . PHE A 1 336 ? 107.418 101.452 101.471 1.00 48.17  ? 336 PHE A CA   1 
ATOM   2491 C  C    . PHE A 1 336 ? 108.596 102.239 100.932 1.00 48.17  ? 336 PHE A C    1 
ATOM   2492 O  O    . PHE A 1 336 ? 108.478 102.940 99.921  1.00 48.17  ? 336 PHE A O    1 
ATOM   2493 C  CB   . PHE A 1 336 ? 106.951 102.028 102.801 1.00 48.17  ? 336 PHE A CB   1 
ATOM   2494 C  CG   . PHE A 1 336 ? 106.147 103.273 102.669 1.00 48.17  ? 336 PHE A CG   1 
ATOM   2495 C  CD1  . PHE A 1 336 ? 104.939 103.258 102.018 1.00 48.17  ? 336 PHE A CD1  1 
ATOM   2496 C  CD2  . PHE A 1 336 ? 106.597 104.456 103.208 1.00 48.17  ? 336 PHE A CD2  1 
ATOM   2497 C  CE1  . PHE A 1 336 ? 104.195 104.400 101.905 1.00 48.17  ? 336 PHE A CE1  1 
ATOM   2498 C  CE2  . PHE A 1 336 ? 105.857 105.601 103.096 1.00 48.17  ? 336 PHE A CE2  1 
ATOM   2499 C  CZ   . PHE A 1 336 ? 104.656 105.574 102.440 1.00 48.17  ? 336 PHE A CZ   1 
ATOM   2500 N  N    . LEU A 1 337 ? 109.769 102.062 101.546 1.00 52.26  ? 337 LEU A N    1 
ATOM   2501 C  CA   . LEU A 1 337 ? 110.941 102.776 101.064 1.00 52.26  ? 337 LEU A CA   1 
ATOM   2502 C  C    . LEU A 1 337 ? 111.296 102.339 99.654  1.00 52.26  ? 337 LEU A C    1 
ATOM   2503 O  O    . LEU A 1 337 ? 111.532 103.180 98.779  1.00 52.26  ? 337 LEU A O    1 
ATOM   2504 C  CB   . LEU A 1 337 ? 112.116 102.563 102.012 1.00 52.26  ? 337 LEU A CB   1 
ATOM   2505 C  CG   . LEU A 1 337 ? 111.971 103.275 103.354 1.00 52.26  ? 337 LEU A CG   1 
ATOM   2506 C  CD1  . LEU A 1 337 ? 113.258 103.160 104.139 1.00 52.26  ? 337 LEU A CD1  1 
ATOM   2507 C  CD2  . LEU A 1 337 ? 111.588 104.724 103.154 1.00 52.26  ? 337 LEU A CD2  1 
ATOM   2508 N  N    . ASP A 1 338 ? 111.263 101.032 99.391  1.00 56.31  ? 338 ASP A N    1 
ATOM   2509 C  CA   . ASP A 1 338 ? 111.614 100.569 98.060  1.00 56.31  ? 338 ASP A CA   1 
ATOM   2510 C  C    . ASP A 1 338 ? 110.506 100.935 97.078  1.00 56.31  ? 338 ASP A C    1 
ATOM   2511 O  O    . ASP A 1 338 ? 110.724 100.938 95.866  1.00 56.31  ? 338 ASP A O    1 
ATOM   2512 C  CB   . ASP A 1 338 ? 111.894 99.063  98.116  1.00 56.31  ? 338 ASP A CB   1 
ATOM   2513 C  CG   . ASP A 1 338 ? 112.502 98.500  96.836  1.00 56.31  ? 338 ASP A CG   1 
ATOM   2514 O  OD1  . ASP A 1 338 ? 112.711 99.223  95.849  1.00 56.31  ? 338 ASP A OD1  1 
ATOM   2515 O  OD2  . ASP A 1 338 ? 112.818 97.297  96.827  1.00 56.31  ? 338 ASP A OD2  1 
ATOM   2516 N  N    . GLN A 1 339 ? 109.332 101.308 97.579  1.00 51.91  ? 339 GLN A N    1 
ATOM   2517 C  CA   . GLN A 1 339 ? 108.329 101.885 96.705  1.00 51.91  ? 339 GLN A CA   1 
ATOM   2518 C  C    . GLN A 1 339 ? 108.352 103.396 96.707  1.00 51.91  ? 339 GLN A C    1 
ATOM   2519 O  O    . GLN A 1 339 ? 107.821 104.002 95.769  1.00 51.91  ? 339 GLN A O    1 
ATOM   2520 C  CB   . GLN A 1 339 ? 106.934 101.427 97.100  1.00 51.91  ? 339 GLN A CB   1 
ATOM   2521 C  CG   . GLN A 1 339 ? 106.661 100.031 96.708  1.00 51.91  ? 339 GLN A CG   1 
ATOM   2522 C  CD   . GLN A 1 339 ? 105.254 99.838  96.229  1.00 51.91  ? 339 GLN A CD   1 
ATOM   2523 O  OE1  . GLN A 1 339 ? 104.523 100.801 96.009  1.00 51.91  ? 339 GLN A OE1  1 
ATOM   2524 N  NE2  . GLN A 1 339 ? 104.866 98.588  96.044  1.00 51.91  ? 339 GLN A NE2  1 
ATOM   2525 N  N    . TYR A 1 340 ? 108.921 104.023 97.737  1.00 52.13  ? 340 TYR A N    1 
ATOM   2526 C  CA   . TYR A 1 340 ? 108.999 105.475 97.709  1.00 52.13  ? 340 TYR A CA   1 
ATOM   2527 C  C    . TYR A 1 340 ? 109.932 105.934 96.609  1.00 52.13  ? 340 TYR A C    1 
ATOM   2528 O  O    . TYR A 1 340 ? 109.639 106.900 95.899  1.00 52.13  ? 340 TYR A O    1 
ATOM   2529 C  CB   . TYR A 1 340 ? 109.464 106.043 99.040  1.00 52.13  ? 340 TYR A CB   1 
ATOM   2530 C  CG   . TYR A 1 340 ? 109.695 107.511 98.898  1.00 52.13  ? 340 TYR A CG   1 
ATOM   2531 C  CD1  . TYR A 1 340 ? 108.644 108.357 98.619  1.00 52.13  ? 340 TYR A CD1  1 
ATOM   2532 C  CD2  . TYR A 1 340 ? 110.966 108.041 98.963  1.00 52.13  ? 340 TYR A CD2  1 
ATOM   2533 C  CE1  . TYR A 1 340 ? 108.839 109.690 98.455  1.00 52.13  ? 340 TYR A CE1  1 
ATOM   2534 C  CE2  . TYR A 1 340 ? 111.173 109.379 98.794  1.00 52.13  ? 340 TYR A CE2  1 
ATOM   2535 C  CZ   . TYR A 1 340 ? 110.102 110.198 98.545  1.00 52.13  ? 340 TYR A CZ   1 
ATOM   2536 O  OH   . TYR A 1 340 ? 110.292 111.545 98.376  1.00 52.13  ? 340 TYR A OH   1 
ATOM   2537 N  N    . PHE A 1 341 ? 111.051 105.243 96.439  1.00 55.54  ? 341 PHE A N    1 
ATOM   2538 C  CA   . PHE A 1 341 ? 111.921 105.495 95.304  1.00 55.54  ? 341 PHE A CA   1 
ATOM   2539 C  C    . PHE A 1 341 ? 111.289 104.815 94.095  1.00 55.54  ? 341 PHE A C    1 
ATOM   2540 O  O    . PHE A 1 341 ? 110.162 104.320 94.150  1.00 55.54  ? 341 PHE A O    1 
ATOM   2541 C  CB   . PHE A 1 341 ? 113.319 104.953 95.568  1.00 55.54  ? 341 PHE A CB   1 
ATOM   2542 C  CG   . PHE A 1 341 ? 113.906 105.396 96.867  1.00 55.54  ? 341 PHE A CG   1 
ATOM   2543 C  CD1  . PHE A 1 341 ? 114.084 106.732 97.152  1.00 55.54  ? 341 PHE A CD1  1 
ATOM   2544 C  CD2  . PHE A 1 341 ? 114.309 104.462 97.796  1.00 55.54  ? 341 PHE A CD2  1 
ATOM   2545 C  CE1  . PHE A 1 341 ? 114.625 107.124 98.358  1.00 55.54  ? 341 PHE A CE1  1 
ATOM   2546 C  CE2  . PHE A 1 341 ? 114.856 104.846 98.993  1.00 55.54  ? 341 PHE A CE2  1 
ATOM   2547 C  CZ   . PHE A 1 341 ? 115.014 106.175 99.278  1.00 55.54  ? 341 PHE A CZ   1 
ATOM   2548 N  N    . ASN A 1 342 ? 112.010 104.753 92.987  1.00 63.23  ? 342 ASN A N    1 
ATOM   2549 C  CA   . ASN A 1 342 ? 111.642 103.744 92.021  1.00 63.23  ? 342 ASN A CA   1 
ATOM   2550 C  C    . ASN A 1 342 ? 112.048 102.381 92.561  1.00 63.23  ? 342 ASN A C    1 
ATOM   2551 O  O    . ASN A 1 342 ? 112.695 102.264 93.606  1.00 63.23  ? 342 ASN A O    1 
ATOM   2552 C  CB   . ASN A 1 342 ? 112.296 104.020 90.674  1.00 63.23  ? 342 ASN A CB   1 
ATOM   2553 C  CG   . ASN A 1 342 ? 111.787 105.290 90.043  1.00 63.23  ? 342 ASN A CG   1 
ATOM   2554 O  OD1  . ASN A 1 342 ? 110.613 105.633 90.179  1.00 63.23  ? 342 ASN A OD1  1 
ATOM   2555 N  ND2  . ASN A 1 342 ? 112.667 105.998 89.350  1.00 63.23  ? 342 ASN A ND2  1 
ATOM   2556 N  N    . ASN A 1 343 ? 111.691 101.330 91.833  1.00 69.87  ? 343 ASN A N    1 
ATOM   2557 C  CA   . ASN A 1 343 ? 111.961 99.978  92.307  1.00 69.87  ? 343 ASN A CA   1 
ATOM   2558 C  C    . ASN A 1 343 ? 113.457 100.221 92.138  1.00 69.87  ? 343 ASN A C    1 
ATOM   2559 O  O    . ASN A 1 343 ? 113.947 100.626 91.081  1.00 69.87  ? 343 ASN A O    1 
ATOM   2560 C  CB   . ASN A 1 343 ? 111.166 98.963  91.502  1.00 69.87  ? 343 ASN A CB   1 
ATOM   2561 C  CG   . ASN A 1 343 ? 109.674 99.122  91.697  1.00 69.87  ? 343 ASN A CG   1 
ATOM   2562 O  OD1  . ASN A 1 343 ? 109.179 100.234 91.864  1.00 69.87  ? 343 ASN A OD1  1 
ATOM   2563 N  ND2  . ASN A 1 343 ? 108.950 98.011  91.687  1.00 69.87  ? 343 ASN A ND2  1 
ATOM   2564 N  N    . PHE A 1 344 ? 114.187 99.976  93.231  1.00 72.12  ? 344 PHE A N    1 
ATOM   2565 C  CA   . PHE A 1 344 ? 115.623 100.222 93.267  1.00 72.12  ? 344 PHE A CA   1 
ATOM   2566 C  C    . PHE A 1 344 ? 116.097 98.784  93.403  1.00 72.12  ? 344 PHE A C    1 
ATOM   2567 O  O    . PHE A 1 344 ? 117.083 98.387  92.775  1.00 72.12  ? 344 PHE A O    1 
ATOM   2568 C  CB   . PHE A 1 344 ? 116.139 101.076 94.420  1.00 72.12  ? 344 PHE A CB   1 
ATOM   2569 C  CG   . PHE A 1 344 ? 117.582 100.853 94.742  1.00 72.12  ? 344 PHE A CG   1 
ATOM   2570 C  CD1  . PHE A 1 344 ? 118.565 101.098 93.799  1.00 72.12  ? 344 PHE A CD1  1 
ATOM   2571 C  CD2  . PHE A 1 344 ? 117.960 100.416 95.998  1.00 72.12  ? 344 PHE A CD2  1 
ATOM   2572 C  CE1  . PHE A 1 344 ? 119.900 100.899 94.101  1.00 72.12  ? 344 PHE A CE1  1 
ATOM   2573 C  CE2  . PHE A 1 344 ? 119.291 100.216 96.305  1.00 72.12  ? 344 PHE A CE2  1 
ATOM   2574 C  CZ   . PHE A 1 344 ? 120.263 100.458 95.356  1.00 72.12  ? 344 PHE A CZ   1 
ATOM   2575 N  N    . ILE A 1 345 ? 115.418 98.001  94.226  1.00 64.76  ? 345 ILE A N    1 
ATOM   2576 C  CA   . ILE A 1 345 ? 115.576 96.558  94.249  1.00 64.76  ? 345 ILE A CA   1 
ATOM   2577 C  C    . ILE A 1 345 ? 114.265 95.960  93.768  1.00 64.76  ? 345 ILE A C    1 
ATOM   2578 O  O    . ILE A 1 345 ? 113.193 96.540  93.977  1.00 64.76  ? 345 ILE A O    1 
ATOM   2579 C  CB   . ILE A 1 345 ? 115.954 96.051  95.655  1.00 64.76  ? 345 ILE A CB   1 
ATOM   2580 C  CG1  . ILE A 1 345 ? 117.028 96.953  96.259  1.00 64.76  ? 345 ILE A CG1  1 
ATOM   2581 C  CG2  . ILE A 1 345 ? 116.503 94.647  95.580  1.00 64.76  ? 345 ILE A CG2  1 
ATOM   2582 C  CD1  . ILE A 1 345 ? 117.518 96.512  97.622  1.00 64.76  ? 345 ILE A CD1  1 
ATOM   2583 N  N    . ASP A 1 346 ? 114.353 94.821  93.081  1.00 63.35  ? 346 ASP A N    1 
ATOM   2584 C  CA   . ASP A 1 346 ? 113.162 94.163  92.553  1.00 63.35  ? 346 ASP A CA   1 
ATOM   2585 C  C    . ASP A 1 346 ? 112.201 93.821  93.683  1.00 63.35  ? 346 ASP A C    1 
ATOM   2586 O  O    . ASP A 1 346 ? 112.603 93.274  94.713  1.00 63.35  ? 346 ASP A O    1 
ATOM   2587 C  CB   . ASP A 1 346 ? 113.548 92.897  91.794  1.00 63.35  ? 346 ASP A CB   1 
ATOM   2588 C  CG   . ASP A 1 346 ? 112.560 92.552  90.703  1.00 63.35  ? 346 ASP A CG   1 
ATOM   2589 O  OD1  . ASP A 1 346 ? 111.546 93.266  90.575  1.00 63.35  ? 346 ASP A OD1  1 
ATOM   2590 O  OD2  . ASP A 1 346 ? 112.801 91.568  89.973  1.00 63.35  ? 346 ASP A OD2  1 
ATOM   2591 N  N    . GLU A 1 347 ? 110.924 94.151  93.482  1.00 60.04  ? 347 GLU A N    1 
ATOM   2592 C  CA   . GLU A 1 347 ? 109.976 94.180  94.592  1.00 60.04  ? 347 GLU A CA   1 
ATOM   2593 C  C    . GLU A 1 347 ? 109.724 92.801  95.174  1.00 60.04  ? 347 GLU A C    1 
ATOM   2594 O  O    . GLU A 1 347 ? 109.464 92.678  96.375  1.00 60.04  ? 347 GLU A O    1 
ATOM   2595 C  CB   . GLU A 1 347 ? 108.663 94.787  94.136  1.00 60.04  ? 347 GLU A CB   1 
ATOM   2596 C  CG   . GLU A 1 347 ? 107.887 95.419  95.242  1.00 60.04  ? 347 GLU A CG   1 
ATOM   2597 C  CD   . GLU A 1 347 ? 106.799 96.287  94.705  1.00 60.04  ? 347 GLU A CD   1 
ATOM   2598 O  OE1  . GLU A 1 347 ? 106.862 97.505  94.921  1.00 60.04  ? 347 GLU A OE1  1 
ATOM   2599 O  OE2  . GLU A 1 347 ? 105.895 95.755  94.032  1.00 60.04  ? 347 GLU A OE2  1 
ATOM   2600 N  N    . TYR A 1 348 ? 109.777 91.763  94.350  1.00 54.72  ? 348 TYR A N    1 
ATOM   2601 C  CA   . TYR A 1 348 ? 109.601 90.413  94.864  1.00 54.72  ? 348 TYR A CA   1 
ATOM   2602 C  C    . TYR A 1 348 ? 110.719 90.047  95.833  1.00 54.72  ? 348 TYR A C    1 
ATOM   2603 O  O    . TYR A 1 348 ? 110.473 89.436  96.883  1.00 54.72  ? 348 TYR A O    1 
ATOM   2604 C  CB   . TYR A 1 348 ? 109.505 89.439  93.691  1.00 54.72  ? 348 TYR A CB   1 
ATOM   2605 C  CG   . TYR A 1 348 ? 109.803 88.002  94.010  1.00 54.72  ? 348 TYR A CG   1 
ATOM   2606 C  CD1  . TYR A 1 348 ? 108.856 87.187  94.596  1.00 54.72  ? 348 TYR A CD1  1 
ATOM   2607 C  CD2  . TYR A 1 348 ? 111.023 87.446  93.673  1.00 54.72  ? 348 TYR A CD2  1 
ATOM   2608 C  CE1  . TYR A 1 348 ? 109.134 85.868  94.875  1.00 54.72  ? 348 TYR A CE1  1 
ATOM   2609 C  CE2  . TYR A 1 348 ? 111.308 86.129  93.942  1.00 54.72  ? 348 TYR A CE2  1 
ATOM   2610 C  CZ   . TYR A 1 348 ? 110.362 85.344  94.544  1.00 54.72  ? 348 TYR A CZ   1 
ATOM   2611 O  OH   . TYR A 1 348 ? 110.648 84.028  94.812  1.00 54.72  ? 348 TYR A OH   1 
ATOM   2612 N  N    . VAL A 1 349 ? 111.948 90.467  95.532  1.00 55.68  ? 349 VAL A N    1 
ATOM   2613 C  CA   . VAL A 1 349 ? 113.079 90.124  96.387  1.00 55.68  ? 349 VAL A CA   1 
ATOM   2614 C  C    . VAL A 1 349 ? 113.014 90.882  97.708  1.00 55.68  ? 349 VAL A C    1 
ATOM   2615 O  O    . VAL A 1 349 ? 113.280 90.314  98.775  1.00 55.68  ? 349 VAL A O    1 
ATOM   2616 C  CB   . VAL A 1 349 ? 114.400 90.376  95.649  1.00 55.68  ? 349 VAL A CB   1 
ATOM   2617 C  CG1  . VAL A 1 349 ? 115.568 89.924  96.502  1.00 55.68  ? 349 VAL A CG1  1 
ATOM   2618 C  CG2  . VAL A 1 349 ? 114.402 89.627  94.344  1.00 55.68  ? 349 VAL A CG2  1 
ATOM   2619 N  N    . VAL A 1 350 ? 112.655 92.167  97.671  1.00 54.01  ? 350 VAL A N    1 
ATOM   2620 C  CA   . VAL A 1 350 ? 112.525 92.902  98.925  1.00 54.01  ? 350 VAL A CA   1 
ATOM   2621 C  C    . VAL A 1 350 ? 111.319 92.414  99.718  1.00 54.01  ? 350 VAL A C    1 
ATOM   2622 O  O    . VAL A 1 350 ? 111.320 92.472  100.951 1.00 54.01  ? 350 VAL A O    1 
ATOM   2623 C  CB   . VAL A 1 350 ? 112.479 94.420  98.670  1.00 54.01  ? 350 VAL A CB   1 
ATOM   2624 C  CG1  . VAL A 1 350 ? 111.170 94.827  98.054  1.00 54.01  ? 350 VAL A CG1  1 
ATOM   2625 C  CG2  . VAL A 1 350 ? 112.714 95.189  99.956  1.00 54.01  ? 350 VAL A CG2  1 
ATOM   2626 N  N    . LEU A 1 351 ? 110.289 91.897  99.044  1.00 50.22  ? 351 LEU A N    1 
ATOM   2627 C  CA   . LEU A 1 351 ? 109.172 91.301  99.765  1.00 50.22  ? 351 LEU A CA   1 
ATOM   2628 C  C    . LEU A 1 351 ? 109.608 90.043  100.499 1.00 50.22  ? 351 LEU A C    1 
ATOM   2629 O  O    . LEU A 1 351 ? 109.202 89.814  101.642 1.00 50.22  ? 351 LEU A O    1 
ATOM   2630 C  CB   . LEU A 1 351 ? 108.030 90.990  98.804  1.00 50.22  ? 351 LEU A CB   1 
ATOM   2631 C  CG   . LEU A 1 351 ? 106.801 90.373  99.445  1.00 50.22  ? 351 LEU A CG   1 
ATOM   2632 C  CD1  . LEU A 1 351 ? 106.203 91.355  100.406 1.00 50.22  ? 351 LEU A CD1  1 
ATOM   2633 C  CD2  . LEU A 1 351 ? 105.808 90.017  98.387  1.00 50.22  ? 351 LEU A CD2  1 
ATOM   2634 N  N    . TRP A 1 352 ? 110.437 89.217  99.864  1.00 50.06  ? 352 TRP A N    1 
ATOM   2635 C  CA   . TRP A 1 352 ? 110.963 88.046  100.561 1.00 50.06  ? 352 TRP A CA   1 
ATOM   2636 C  C    . TRP A 1 352 ? 111.892 88.437  101.700 1.00 50.06  ? 352 TRP A C    1 
ATOM   2637 O  O    . TRP A 1 352 ? 111.916 87.777  102.747 1.00 50.06  ? 352 TRP A O    1 
ATOM   2638 C  CB   . TRP A 1 352 ? 111.678 87.132  99.583  1.00 50.06  ? 352 TRP A CB   1 
ATOM   2639 C  CG   . TRP A 1 352 ? 110.858 85.981  99.214  1.00 50.06  ? 352 TRP A CG   1 
ATOM   2640 C  CD1  . TRP A 1 352 ? 110.099 85.846  98.106  1.00 50.06  ? 352 TRP A CD1  1 
ATOM   2641 C  CD2  . TRP A 1 352 ? 110.710 84.776  99.957  1.00 50.06  ? 352 TRP A CD2  1 
ATOM   2642 N  NE1  . TRP A 1 352 ? 109.477 84.628  98.104  1.00 50.06  ? 352 TRP A NE1  1 
ATOM   2643 C  CE2  . TRP A 1 352 ? 109.839 83.951  99.236  1.00 50.06  ? 352 TRP A CE2  1 
ATOM   2644 C  CE3  . TRP A 1 352 ? 111.232 84.314  101.163 1.00 50.06  ? 352 TRP A CE3  1 
ATOM   2645 C  CZ2  . TRP A 1 352 ? 109.475 82.690  99.676  1.00 50.06  ? 352 TRP A CZ2  1 
ATOM   2646 C  CZ3  . TRP A 1 352 ? 110.871 83.063  101.600 1.00 50.06  ? 352 TRP A CZ3  1 
ATOM   2647 C  CH2  . TRP A 1 352 ? 110.000 82.264  100.860 1.00 50.06  ? 352 TRP A CH2  1 
ATOM   2648 N  N    . MET A 1 353 ? 112.676 89.499  101.518 1.00 54.85  ? 353 MET A N    1 
ATOM   2649 C  CA   . MET A 1 353 ? 113.498 89.980  102.623 1.00 54.85  ? 353 MET A CA   1 
ATOM   2650 C  C    . MET A 1 353 ? 112.626 90.456  103.777 1.00 54.85  ? 353 MET A C    1 
ATOM   2651 O  O    . MET A 1 353 ? 112.956 90.228  104.948 1.00 54.85  ? 353 MET A O    1 
ATOM   2652 C  CB   . MET A 1 353 ? 114.439 91.087  102.153 1.00 54.85  ? 353 MET A CB   1 
ATOM   2653 C  CG   . MET A 1 353 ? 115.814 90.582  101.729 1.00 54.85  ? 353 MET A CG   1 
ATOM   2654 S  SD   . MET A 1 353 ? 116.752 89.852  103.089 1.00 54.85  ? 353 MET A SD   1 
ATOM   2655 C  CE   . MET A 1 353 ? 117.663 88.558  102.247 1.00 54.85  ? 353 MET A CE   1 
ATOM   2656 N  N    . ALA A 1 354 ? 111.506 91.110  103.467 1.00 50.47  ? 354 ALA A N    1 
ATOM   2657 C  CA   . ALA A 1 354 ? 110.584 91.547  104.507 1.00 50.47  ? 354 ALA A CA   1 
ATOM   2658 C  C    . ALA A 1 354 ? 109.953 90.360  105.222 1.00 50.47  ? 354 ALA A C    1 
ATOM   2659 O  O    . ALA A 1 354 ? 109.812 90.381  106.449 1.00 50.47  ? 354 ALA A O    1 
ATOM   2660 C  CB   . ALA A 1 354 ? 109.515 92.453  103.913 1.00 50.47  ? 354 ALA A CB   1 
ATOM   2661 N  N    . MET A 1 355 ? 109.555 89.330  104.470 1.00 51.01  ? 355 MET A N    1 
ATOM   2662 C  CA   . MET A 1 355 ? 109.202 88.030  105.036 1.00 51.01  ? 355 MET A CA   1 
ATOM   2663 C  C    . MET A 1 355 ? 110.209 87.549  106.066 1.00 51.01  ? 355 MET A C    1 
ATOM   2664 O  O    . MET A 1 355 ? 109.851 87.251  107.208 1.00 51.01  ? 355 MET A O    1 
ATOM   2665 C  CB   . MET A 1 355 ? 109.094 86.982  103.924 1.00 51.01  ? 355 MET A CB   1 
ATOM   2666 C  CG   . MET A 1 355 ? 108.499 85.627  104.323 1.00 51.01  ? 355 MET A CG   1 
ATOM   2667 S  SD   . MET A 1 355 ? 107.186 85.516  105.532 1.00 51.01  ? 355 MET A SD   1 
ATOM   2668 C  CE   . MET A 1 355 ? 105.967 86.523  104.737 1.00 51.01  ? 355 MET A CE   1 
ATOM   2669 N  N    . VAL A 1 356 ? 111.480 87.475  105.671 1.00 54.30  ? 356 VAL A N    1 
ATOM   2670 C  CA   . VAL A 1 356 ? 112.488 86.895  106.554 1.00 54.30  ? 356 VAL A CA   1 
ATOM   2671 C  C    . VAL A 1 356 ? 112.678 87.754  107.801 1.00 54.30  ? 356 VAL A C    1 
ATOM   2672 O  O    . VAL A 1 356 ? 112.681 87.239  108.929 1.00 54.30  ? 356 VAL A O    1 
ATOM   2673 C  CB   . VAL A 1 356 ? 113.806 86.680  105.793 1.00 54.30  ? 356 VAL A CB   1 
ATOM   2674 C  CG1  . VAL A 1 356 ? 114.964 86.529  106.761 1.00 54.30  ? 356 VAL A CG1  1 
ATOM   2675 C  CG2  . VAL A 1 356 ? 113.699 85.446  104.927 1.00 54.30  ? 356 VAL A CG2  1 
ATOM   2676 N  N    . ILE A 1 357 ? 112.795 89.075  107.630 1.00 54.56  ? 357 ILE A N    1 
ATOM   2677 C  CA   . ILE A 1 357 ? 113.088 89.924  108.783 1.00 54.56  ? 357 ILE A CA   1 
ATOM   2678 C  C    . ILE A 1 357 ? 111.898 89.978  109.739 1.00 54.56  ? 357 ILE A C    1 
ATOM   2679 O  O    . ILE A 1 357 ? 112.067 89.870  110.961 1.00 54.56  ? 357 ILE A O    1 
ATOM   2680 C  CB   . ILE A 1 357 ? 113.549 91.328  108.340 1.00 54.56  ? 357 ILE A CB   1 
ATOM   2681 C  CG1  . ILE A 1 357 ? 113.912 92.176  109.553 1.00 54.56  ? 357 ILE A CG1  1 
ATOM   2682 C  CG2  . ILE A 1 357 ? 112.501 92.056  107.539 1.00 54.56  ? 357 ILE A CG2  1 
ATOM   2683 C  CD1  . ILE A 1 357 ? 114.387 93.566  109.197 1.00 54.56  ? 357 ILE A CD1  1 
ATOM   2684 N  N    . SER A 1 358 ? 110.676 90.099  109.211 1.00 54.63  ? 358 SER A N    1 
ATOM   2685 C  CA   . SER A 1 358 ? 109.506 90.143  110.075 1.00 54.63  ? 358 SER A CA   1 
ATOM   2686 C  C    . SER A 1 358 ? 109.276 88.807  110.764 1.00 54.63  ? 358 SER A C    1 
ATOM   2687 O  O    . SER A 1 358 ? 108.920 88.772  111.945 1.00 54.63  ? 358 SER A O    1 
ATOM   2688 C  CB   . SER A 1 358 ? 108.277 90.552  109.275 1.00 54.63  ? 358 SER A CB   1 
ATOM   2689 O  OG   . SER A 1 358 ? 107.098 90.269  109.999 1.00 54.63  ? 358 SER A OG   1 
ATOM   2690 N  N    . SER A 1 359 ? 109.482 87.698  110.048 1.00 55.90  ? 359 SER A N    1 
ATOM   2691 C  CA   . SER A 1 359 ? 109.307 86.388  110.657 1.00 55.90  ? 359 SER A CA   1 
ATOM   2692 C  C    . SER A 1 359 ? 110.292 86.166  111.794 1.00 55.90  ? 359 SER A C    1 
ATOM   2693 O  O    . SER A 1 359 ? 109.896 85.719  112.878 1.00 55.90  ? 359 SER A O    1 
ATOM   2694 C  CB   . SER A 1 359 ? 109.458 85.301  109.599 1.00 55.90  ? 359 SER A CB   1 
ATOM   2695 O  OG   . SER A 1 359 ? 109.439 84.016  110.190 1.00 55.90  ? 359 SER A OG   1 
ATOM   2696 N  N    . PHE A 1 360 ? 111.576 86.479  111.579 1.00 60.75  ? 360 PHE A N    1 
ATOM   2697 C  CA   . PHE A 1 360 ? 112.534 86.326  112.669 1.00 60.75  ? 360 PHE A CA   1 
ATOM   2698 C  C    . PHE A 1 360 ? 112.231 87.247  113.839 1.00 60.75  ? 360 PHE A C    1 
ATOM   2699 O  O    . PHE A 1 360 ? 112.334 86.821  114.992 1.00 60.75  ? 360 PHE A O    1 
ATOM   2700 C  CB   . PHE A 1 360 ? 113.971 86.533  112.197 1.00 60.75  ? 360 PHE A CB   1 
ATOM   2701 C  CG   . PHE A 1 360 ? 114.585 85.325  111.570 1.00 60.75  ? 360 PHE A CG   1 
ATOM   2702 C  CD1  . PHE A 1 360 ? 115.047 84.296  112.371 1.00 60.75  ? 360 PHE A CD1  1 
ATOM   2703 C  CD2  . PHE A 1 360 ? 114.743 85.226  110.204 1.00 60.75  ? 360 PHE A CD2  1 
ATOM   2704 C  CE1  . PHE A 1 360 ? 115.630 83.179  111.822 1.00 60.75  ? 360 PHE A CE1  1 
ATOM   2705 C  CE2  . PHE A 1 360 ? 115.329 84.108  109.648 1.00 60.75  ? 360 PHE A CE2  1 
ATOM   2706 C  CZ   . PHE A 1 360 ? 115.774 83.083  110.460 1.00 60.75  ? 360 PHE A CZ   1 
ATOM   2707 N  N    . ASP A 1 361 ? 111.859 88.505  113.584 1.00 64.11  ? 361 ASP A N    1 
ATOM   2708 C  CA   . ASP A 1 361 ? 111.588 89.391  114.713 1.00 64.11  ? 361 ASP A CA   1 
ATOM   2709 C  C    . ASP A 1 361 ? 110.367 88.932  115.503 1.00 64.11  ? 361 ASP A C    1 
ATOM   2710 O  O    . ASP A 1 361 ? 110.389 88.937  116.741 1.00 64.11  ? 361 ASP A O    1 
ATOM   2711 C  CB   . ASP A 1 361 ? 111.438 90.834  114.243 1.00 64.11  ? 361 ASP A CB   1 
ATOM   2712 C  CG   . ASP A 1 361 ? 112.750 91.598  114.293 1.00 64.11  ? 361 ASP A CG   1 
ATOM   2713 O  OD1  . ASP A 1 361 ? 113.624 91.225  115.100 1.00 64.11  ? 361 ASP A OD1  1 
ATOM   2714 O  OD2  . ASP A 1 361 ? 112.907 92.578  113.538 1.00 64.11  ? 361 ASP A OD2  1 
ATOM   2715 N  N    . MET A 1 362 ? 109.312 88.486  114.815 1.00 61.19  ? 362 MET A N    1 
ATOM   2716 C  CA   . MET A 1 362 ? 108.133 87.989  115.516 1.00 61.19  ? 362 MET A CA   1 
ATOM   2717 C  C    . MET A 1 362 ? 108.453 86.735  116.318 1.00 61.19  ? 362 MET A C    1 
ATOM   2718 O  O    . MET A 1 362 ? 108.064 86.620  117.488 1.00 61.19  ? 362 MET A O    1 
ATOM   2719 C  CB   . MET A 1 362 ? 107.010 87.709  114.521 1.00 61.19  ? 362 MET A CB   1 
ATOM   2720 C  CG   . MET A 1 362 ? 105.651 87.489  115.160 1.00 61.19  ? 362 MET A CG   1 
ATOM   2721 S  SD   . MET A 1 362 ? 105.317 85.772  115.587 1.00 61.19  ? 362 MET A SD   1 
ATOM   2722 C  CE   . MET A 1 362 ? 104.360 85.254  114.174 1.00 61.19  ? 362 MET A CE   1 
ATOM   2723 N  N    . VAL A 1 363 ? 109.158 85.782  115.706 1.00 61.03  ? 363 VAL A N    1 
ATOM   2724 C  CA   . VAL A 1 363 ? 109.462 84.531  116.389 1.00 61.03  ? 363 VAL A CA   1 
ATOM   2725 C  C    . VAL A 1 363 ? 110.364 84.780  117.590 1.00 61.03  ? 363 VAL A C    1 
ATOM   2726 O  O    . VAL A 1 363 ? 110.150 84.214  118.672 1.00 61.03  ? 363 VAL A O    1 
ATOM   2727 C  CB   . VAL A 1 363 ? 110.082 83.531  115.398 1.00 61.03  ? 363 VAL A CB   1 
ATOM   2728 C  CG1  . VAL A 1 363 ? 110.872 82.460  116.121 1.00 61.03  ? 363 VAL A CG1  1 
ATOM   2729 C  CG2  . VAL A 1 363 ? 108.995 82.902  114.563 1.00 61.03  ? 363 VAL A CG2  1 
ATOM   2730 N  N    . ILE A 1 364 ? 111.372 85.640  117.429 1.00 66.19  ? 364 ILE A N    1 
ATOM   2731 C  CA   . ILE A 1 364 ? 112.279 85.950  118.527 1.00 66.19  ? 364 ILE A CA   1 
ATOM   2732 C  C    . ILE A 1 364 ? 111.530 86.627  119.663 1.00 66.19  ? 364 ILE A C    1 
ATOM   2733 O  O    . ILE A 1 364 ? 111.703 86.260  120.833 1.00 66.19  ? 364 ILE A O    1 
ATOM   2734 C  CB   . ILE A 1 364 ? 113.451 86.807  118.017 1.00 66.19  ? 364 ILE A CB   1 
ATOM   2735 C  CG1  . ILE A 1 364 ? 114.454 85.922  117.280 1.00 66.19  ? 364 ILE A CG1  1 
ATOM   2736 C  CG2  . ILE A 1 364 ? 114.124 87.541  119.153 1.00 66.19  ? 364 ILE A CG2  1 
ATOM   2737 C  CD1  . ILE A 1 364 ? 114.997 84.789  118.122 1.00 66.19  ? 364 ILE A CD1  1 
ATOM   2738 N  N    . TYR A 1 365 ? 110.656 87.585  119.344 1.00 66.56  ? 365 TYR A N    1 
ATOM   2739 C  CA   . TYR A 1 365 ? 109.881 88.248  120.387 1.00 66.56  ? 365 TYR A CA   1 
ATOM   2740 C  C    . TYR A 1 365 ? 109.000 87.261  121.131 1.00 66.56  ? 365 TYR A C    1 
ATOM   2741 O  O    . TYR A 1 365 ? 108.936 87.277  122.364 1.00 66.56  ? 365 TYR A O    1 
ATOM   2742 C  CB   . TYR A 1 365 ? 109.016 89.352  119.789 1.00 66.56  ? 365 TYR A CB   1 
ATOM   2743 C  CG   . TYR A 1 365 ? 107.897 89.773  120.710 1.00 66.56  ? 365 TYR A CG   1 
ATOM   2744 C  CD1  . TYR A 1 365 ? 108.156 90.522  121.839 1.00 66.56  ? 365 TYR A CD1  1 
ATOM   2745 C  CD2  . TYR A 1 365 ? 106.584 89.419  120.452 1.00 66.56  ? 365 TYR A CD2  1 
ATOM   2746 C  CE1  . TYR A 1 365 ? 107.147 90.910  122.682 1.00 66.56  ? 365 TYR A CE1  1 
ATOM   2747 C  CE2  . TYR A 1 365 ? 105.570 89.802  121.295 1.00 66.56  ? 365 TYR A CE2  1 
ATOM   2748 C  CZ   . TYR A 1 365 ? 105.861 90.548  122.407 1.00 66.56  ? 365 TYR A CZ   1 
ATOM   2749 O  OH   . TYR A 1 365 ? 104.858 90.939  123.256 1.00 66.56  ? 365 TYR A OH   1 
ATOM   2750 N  N    . PHE A 1 366 ? 108.319 86.384  120.398 1.00 72.15  ? 366 PHE A N    1 
ATOM   2751 C  CA   . PHE A 1 366 ? 107.362 85.493  121.040 1.00 72.15  ? 366 PHE A CA   1 
ATOM   2752 C  C    . PHE A 1 366 ? 108.059 84.445  121.899 1.00 72.15  ? 366 PHE A C    1 
ATOM   2753 O  O    . PHE A 1 366 ? 107.632 84.175  123.032 1.00 72.15  ? 366 PHE A O    1 
ATOM   2754 C  CB   . PHE A 1 366 ? 106.483 84.840  119.979 1.00 72.15  ? 366 PHE A CB   1 
ATOM   2755 C  CG   . PHE A 1 366 ? 105.228 84.259  120.523 1.00 72.15  ? 366 PHE A CG   1 
ATOM   2756 C  CD1  . PHE A 1 366 ? 104.476 84.965  121.437 1.00 72.15  ? 366 PHE A CD1  1 
ATOM   2757 C  CD2  . PHE A 1 366 ? 104.781 83.026  120.102 1.00 72.15  ? 366 PHE A CD2  1 
ATOM   2758 C  CE1  . PHE A 1 366 ? 103.315 84.444  121.942 1.00 72.15  ? 366 PHE A CE1  1 
ATOM   2759 C  CE2  . PHE A 1 366 ? 103.619 82.499  120.602 1.00 72.15  ? 366 PHE A CE2  1 
ATOM   2760 C  CZ   . PHE A 1 366 ? 102.884 83.209  121.524 1.00 72.15  ? 366 PHE A CZ   1 
ATOM   2761 N  N    . SER A 1 367 ? 109.141 83.853  121.388 1.00 78.89  ? 367 SER A N    1 
ATOM   2762 C  CA   . SER A 1 367 ? 109.876 82.876  122.179 1.00 78.89  ? 367 SER A CA   1 
ATOM   2763 C  C    . SER A 1 367 ? 110.537 83.525  123.386 1.00 78.89  ? 367 SER A C    1 
ATOM   2764 O  O    . SER A 1 367 ? 110.569 82.930  124.469 1.00 78.89  ? 367 SER A O    1 
ATOM   2765 C  CB   . SER A 1 367 ? 110.907 82.161  121.313 1.00 78.89  ? 367 SER A CB   1 
ATOM   2766 O  OG   . SER A 1 367 ? 110.284 81.168  120.522 1.00 78.89  ? 367 SER A OG   1 
ATOM   2767 N  N    . ALA A 1 368 ? 111.056 84.745  123.232 1.00 82.16  ? 368 ALA A N    1 
ATOM   2768 C  CA   . ALA A 1 368 ? 111.630 85.445  124.375 1.00 82.16  ? 368 ALA A CA   1 
ATOM   2769 C  C    . ALA A 1 368 ? 110.568 85.738  125.421 1.00 82.16  ? 368 ALA A C    1 
ATOM   2770 O  O    . ALA A 1 368 ? 110.826 85.616  126.624 1.00 82.16  ? 368 ALA A O    1 
ATOM   2771 C  CB   . ALA A 1 368 ? 112.297 86.736  123.916 1.00 82.16  ? 368 ALA A CB   1 
ATOM   2772 N  N    . LEU A 1 369 ? 109.368 86.115  124.983 1.00 83.07  ? 369 LEU A N    1 
ATOM   2773 C  CA   . LEU A 1 369 ? 108.284 86.384  125.916 1.00 83.07  ? 369 LEU A CA   1 
ATOM   2774 C  C    . LEU A 1 369 ? 107.920 85.138  126.704 1.00 83.07  ? 369 LEU A C    1 
ATOM   2775 O  O    . LEU A 1 369 ? 107.812 85.176  127.936 1.00 83.07  ? 369 LEU A O    1 
ATOM   2776 C  CB   . LEU A 1 369 ? 107.068 86.904  125.161 1.00 83.07  ? 369 LEU A CB   1 
ATOM   2777 C  CG   . LEU A 1 369 ? 105.970 87.463  126.051 1.00 83.07  ? 369 LEU A CG   1 
ATOM   2778 C  CD1  . LEU A 1 369 ? 106.441 88.738  126.683 1.00 83.07  ? 369 LEU A CD1  1 
ATOM   2779 C  CD2  . LEU A 1 369 ? 104.737 87.706  125.232 1.00 83.07  ? 369 LEU A CD2  1 
ATOM   2780 N  N    . CYS A 1 370 ? 107.732 84.015  126.006 1.00 92.75  ? 370 CYS A N    1 
ATOM   2781 C  CA   . CYS A 1 370 ? 107.366 82.795  126.717 1.00 92.75  ? 370 CYS A CA   1 
ATOM   2782 C  C    . CYS A 1 370 ? 108.488 82.329  127.635 1.00 92.75  ? 370 CYS A C    1 
ATOM   2783 O  O    . CYS A 1 370 ? 108.220 81.861  128.748 1.00 92.75  ? 370 CYS A O    1 
ATOM   2784 C  CB   . CYS A 1 370 ? 106.985 81.687  125.736 1.00 92.75  ? 370 CYS A CB   1 
ATOM   2785 S  SG   . CYS A 1 370 ? 108.373 80.728  125.095 1.00 92.75  ? 370 CYS A SG   1 
ATOM   2786 N  N    . LEU A 1 371 ? 109.745 82.473  127.205 1.00 91.35  ? 371 LEU A N    1 
ATOM   2787 C  CA   . LEU A 1 371 ? 110.866 82.074  128.047 1.00 91.35  ? 371 LEU A CA   1 
ATOM   2788 C  C    . LEU A 1 371 ? 110.953 82.928  129.303 1.00 91.35  ? 371 LEU A C    1 
ATOM   2789 O  O    . LEU A 1 371 ? 111.201 82.405  130.393 1.00 91.35  ? 371 LEU A O    1 
ATOM   2790 C  CB   . LEU A 1 371 ? 112.169 82.152  127.257 1.00 91.35  ? 371 LEU A CB   1 
ATOM   2791 C  CG   . LEU A 1 371 ? 112.471 80.942  126.374 1.00 91.35  ? 371 LEU A CG   1 
ATOM   2792 C  CD1  . LEU A 1 371 ? 113.818 81.103  125.697 1.00 91.35  ? 371 LEU A CD1  1 
ATOM   2793 C  CD2  . LEU A 1 371 ? 112.425 79.667  127.190 1.00 91.35  ? 371 LEU A CD2  1 
ATOM   2794 N  N    . GLN A 1 372 ? 110.751 84.243  129.174 1.00 97.03  ? 372 GLN A N    1 
ATOM   2795 C  CA   . GLN A 1 372 ? 110.785 85.107  130.350 1.00 97.03  ? 372 GLN A CA   1 
ATOM   2796 C  C    . GLN A 1 372 ? 109.646 84.790  131.303 1.00 97.03  ? 372 GLN A C    1 
ATOM   2797 O  O    . GLN A 1 372 ? 109.842 84.766  132.524 1.00 97.03  ? 372 GLN A O    1 
ATOM   2798 C  CB   . GLN A 1 372 ? 110.726 86.575  129.941 1.00 97.03  ? 372 GLN A CB   1 
ATOM   2799 C  CG   . GLN A 1 372 ? 111.000 87.517  131.093 1.00 97.03  ? 372 GLN A CG   1 
ATOM   2800 C  CD   . GLN A 1 372 ? 110.602 88.942  130.797 1.00 97.03  ? 372 GLN A CD   1 
ATOM   2801 O  OE1  . GLN A 1 372 ? 110.242 89.277  129.674 1.00 97.03  ? 372 GLN A OE1  1 
ATOM   2802 N  NE2  . GLN A 1 372 ? 110.661 89.792  131.810 1.00 97.03  ? 372 GLN A NE2  1 
ATOM   2803 N  N    . ILE A 1 373 ? 108.446 84.546  130.767 1.00 101.25 ? 373 ILE A N    1 
ATOM   2804 C  CA   . ILE A 1 373 ? 107.316 84.214  131.625 1.00 101.25 ? 373 ILE A CA   1 
ATOM   2805 C  C    . ILE A 1 373 ? 107.576 82.904  132.357 1.00 101.25 ? 373 ILE A C    1 
ATOM   2806 O  O    . ILE A 1 373 ? 107.285 82.774  133.552 1.00 101.25 ? 373 ILE A O    1 
ATOM   2807 C  CB   . ILE A 1 373 ? 106.016 84.161  130.803 1.00 101.25 ? 373 ILE A CB   1 
ATOM   2808 C  CG1  . ILE A 1 373 ? 105.675 85.547  130.261 1.00 101.25 ? 373 ILE A CG1  1 
ATOM   2809 C  CG2  . ILE A 1 373 ? 104.870 83.640  131.643 1.00 101.25 ? 373 ILE A CG2  1 
ATOM   2810 C  CD1  . ILE A 1 373 ? 105.221 86.502  131.308 1.00 101.25 ? 373 ILE A CD1  1 
ATOM   2811 N  N    . SER A 1 374 ? 108.145 81.921  131.657 1.00 107.27 ? 374 SER A N    1 
ATOM   2812 C  CA   . SER A 1 374 ? 108.453 80.642  132.290 1.00 107.27 ? 374 SER A CA   1 
ATOM   2813 C  C    . SER A 1 374 ? 109.530 80.785  133.359 1.00 107.27 ? 374 SER A C    1 
ATOM   2814 O  O    . SER A 1 374 ? 109.426 80.185  134.434 1.00 107.27 ? 374 SER A O    1 
ATOM   2815 C  CB   . SER A 1 374 ? 108.891 79.633  131.233 1.00 107.27 ? 374 SER A CB   1 
ATOM   2816 O  OG   . SER A 1 374 ? 110.265 79.798  130.931 1.00 107.27 ? 374 SER A OG   1 
ATOM   2817 N  N    . ARG A 1 375 ? 110.568 81.576  133.085 1.00 111.53 ? 375 ARG A N    1 
ATOM   2818 C  CA   . ARG A 1 375 ? 111.684 81.675  134.020 1.00 111.53 ? 375 ARG A CA   1 
ATOM   2819 C  C    . ARG A 1 375 ? 111.315 82.479  135.257 1.00 111.53 ? 375 ARG A C    1 
ATOM   2820 O  O    . ARG A 1 375 ? 111.755 82.149  136.364 1.00 111.53 ? 375 ARG A O    1 
ATOM   2821 C  CB   . ARG A 1 375 ? 112.899 82.288  133.326 1.00 111.53 ? 375 ARG A CB   1 
ATOM   2822 C  CG   . ARG A 1 375 ? 113.823 81.269  132.676 1.00 111.53 ? 375 ARG A CG   1 
ATOM   2823 C  CD   . ARG A 1 375 ? 115.001 81.943  131.992 1.00 111.53 ? 375 ARG A CD   1 
ATOM   2824 N  NE   . ARG A 1 375 ? 115.720 81.028  131.112 1.00 111.53 ? 375 ARG A NE   1 
ATOM   2825 C  CZ   . ARG A 1 375 ? 116.771 80.305  131.489 1.00 111.53 ? 375 ARG A CZ   1 
ATOM   2826 N  NH1  . ARG A 1 375 ? 117.229 80.394  132.729 1.00 111.53 ? 375 ARG A NH1  1 
ATOM   2827 N  NH2  . ARG A 1 375 ? 117.366 79.494  130.624 1.00 111.53 ? 375 ARG A NH2  1 
ATOM   2828 N  N    . HIS A 1 376 ? 110.523 83.541  135.094 1.00 109.65 ? 376 HIS A N    1 
ATOM   2829 C  CA   . HIS A 1 376 ? 110.150 84.359  136.246 1.00 109.65 ? 376 HIS A CA   1 
ATOM   2830 C  C    . HIS A 1 376 ? 109.276 83.587  137.221 1.00 109.65 ? 376 HIS A C    1 
ATOM   2831 O  O    . HIS A 1 376 ? 109.439 83.705  138.440 1.00 109.65 ? 376 HIS A O    1 
ATOM   2832 C  CB   . HIS A 1 376 ? 109.429 85.622  135.791 1.00 109.65 ? 376 HIS A CB   1 
ATOM   2833 C  CG   . HIS A 1 376 ? 108.703 86.320  136.895 1.00 109.65 ? 376 HIS A CG   1 
ATOM   2834 N  ND1  . HIS A 1 376 ? 107.341 86.220  137.068 1.00 109.65 ? 376 HIS A ND1  1 
ATOM   2835 C  CD2  . HIS A 1 376 ? 109.149 87.122  137.889 1.00 109.65 ? 376 HIS A CD2  1 
ATOM   2836 C  CE1  . HIS A 1 376 ? 106.978 86.928  138.120 1.00 109.65 ? 376 HIS A CE1  1 
ATOM   2837 N  NE2  . HIS A 1 376 ? 108.055 87.490  138.635 1.00 109.65 ? 376 HIS A NE2  1 
ATOM   2838 N  N    . LEU A 1 377 ? 108.344 82.790  136.708 1.00 112.22 ? 377 LEU A N    1 
ATOM   2839 C  CA   . LEU A 1 377 ? 107.465 82.004  137.560 1.00 112.22 ? 377 LEU A CA   1 
ATOM   2840 C  C    . LEU A 1 377 ? 108.101 80.700  138.021 1.00 112.22 ? 377 LEU A C    1 
ATOM   2841 O  O    . LEU A 1 377 ? 107.473 79.977  138.804 1.00 112.22 ? 377 LEU A O    1 
ATOM   2842 C  CB   . LEU A 1 377 ? 106.157 81.710  136.827 1.00 112.22 ? 377 LEU A CB   1 
ATOM   2843 C  CG   . LEU A 1 377 ? 105.382 82.944  136.368 1.00 112.22 ? 377 LEU A CG   1 
ATOM   2844 C  CD1  . LEU A 1 377 ? 104.114 82.540  135.637 1.00 112.22 ? 377 LEU A CD1  1 
ATOM   2845 C  CD2  . LEU A 1 377 ? 105.059 83.827  137.555 1.00 112.22 ? 377 LEU A CD2  1 
ATOM   2846 N  N    . HIS A 1 378 ? 109.321 80.401  137.561 1.00 118.13 ? 378 HIS A N    1 
ATOM   2847 C  CA   . HIS A 1 378 ? 110.018 79.150  137.865 1.00 118.13 ? 378 HIS A CA   1 
ATOM   2848 C  C    . HIS A 1 378 ? 109.166 77.939  137.491 1.00 118.13 ? 378 HIS A C    1 
ATOM   2849 O  O    . HIS A 1 378 ? 109.088 76.949  138.221 1.00 118.13 ? 378 HIS A O    1 
ATOM   2850 C  CB   . HIS A 1 378 ? 110.447 79.092  139.335 1.00 118.13 ? 378 HIS A CB   1 
ATOM   2851 C  CG   . HIS A 1 378 ? 111.534 78.100  139.605 1.00 118.13 ? 378 HIS A CG   1 
ATOM   2852 N  ND1  . HIS A 1 378 ? 112.721 78.086  138.905 1.00 118.13 ? 378 HIS A ND1  1 
ATOM   2853 C  CD2  . HIS A 1 378 ? 111.608 77.078  140.490 1.00 118.13 ? 378 HIS A CD2  1 
ATOM   2854 C  CE1  . HIS A 1 378 ? 113.484 77.103  139.354 1.00 118.13 ? 378 HIS A CE1  1 
ATOM   2855 N  NE2  . HIS A 1 378 ? 112.831 76.477  140.315 1.00 118.13 ? 378 HIS A NE2  1 
ATOM   2856 N  N    . LEU A 1 379 ? 108.510 78.027  136.338 1.00 120.48 ? 379 LEU A N    1 
ATOM   2857 C  CA   . LEU A 1 379 ? 107.652 76.967  135.837 1.00 120.48 ? 379 LEU A CA   1 
ATOM   2858 C  C    . LEU A 1 379 ? 108.097 76.573  134.438 1.00 120.48 ? 379 LEU A C    1 
ATOM   2859 O  O    . LEU A 1 379 ? 108.418 77.433  133.612 1.00 120.48 ? 379 LEU A O    1 
ATOM   2860 C  CB   . LEU A 1 379 ? 106.187 77.405  135.812 1.00 120.48 ? 379 LEU A CB   1 
ATOM   2861 C  CG   . LEU A 1 379 ? 105.173 76.275  135.652 1.00 120.48 ? 379 LEU A CG   1 
ATOM   2862 C  CD1  . LEU A 1 379 ? 105.133 75.423  136.911 1.00 120.48 ? 379 LEU A CD1  1 
ATOM   2863 C  CD2  . LEU A 1 379 ? 103.797 76.830  135.327 1.00 120.48 ? 379 LEU A CD2  1 
ATOM   2864 N  N    . ASN A 1 380 ? 108.121 75.270  134.179 1.00 124.21 ? 380 ASN A N    1 
ATOM   2865 C  CA   . ASN A 1 380 ? 108.452 74.779  132.851 1.00 124.21 ? 380 ASN A CA   1 
ATOM   2866 C  C    . ASN A 1 380 ? 107.345 75.131  131.866 1.00 124.21 ? 380 ASN A C    1 
ATOM   2867 O  O    . ASN A 1 380 ? 106.170 75.239  132.225 1.00 124.21 ? 380 ASN A O    1 
ATOM   2868 C  CB   . ASN A 1 380 ? 108.670 73.266  132.881 1.00 124.21 ? 380 ASN A CB   1 
ATOM   2869 C  CG   . ASN A 1 380 ? 109.555 72.782  131.748 1.00 124.21 ? 380 ASN A CG   1 
ATOM   2870 O  OD1  . ASN A 1 380 ? 110.252 73.570  131.108 1.00 124.21 ? 380 ASN A OD1  1 
ATOM   2871 N  ND2  . ASN A 1 380 ? 109.534 71.477  131.497 1.00 124.21 ? 380 ASN A ND2  1 
ATOM   2872 N  N    . ILE A 1 381 ? 107.737 75.322  130.604 1.00 121.43 ? 381 ILE A N    1 
ATOM   2873 C  CA   . ILE A 1 381 ? 106.754 75.592  129.558 1.00 121.43 ? 381 ILE A CA   1 
ATOM   2874 C  C    . ILE A 1 381 ? 105.854 74.383  129.339 1.00 121.43 ? 381 ILE A C    1 
ATOM   2875 O  O    . ILE A 1 381 ? 104.706 74.527  128.907 1.00 121.43 ? 381 ILE A O    1 
ATOM   2876 C  CB   . ILE A 1 381 ? 107.462 76.033  128.259 1.00 121.43 ? 381 ILE A CB   1 
ATOM   2877 C  CG1  . ILE A 1 381 ? 106.470 76.700  127.306 1.00 121.43 ? 381 ILE A CG1  1 
ATOM   2878 C  CG2  . ILE A 1 381 ? 108.177 74.869  127.590 1.00 121.43 ? 381 ILE A CG2  1 
ATOM   2879 C  CD1  . ILE A 1 381 ? 105.718 77.847  127.923 1.00 121.43 ? 381 ILE A CD1  1 
ATOM   2880 N  N    . PHE A 1 382 ? 106.344 73.184  129.645 1.00 121.52 ? 382 PHE A N    1 
ATOM   2881 C  CA   . PHE A 1 382 ? 105.556 71.964  129.561 1.00 121.52 ? 382 PHE A CA   1 
ATOM   2882 C  C    . PHE A 1 382 ? 105.509 71.319  130.936 1.00 121.52 ? 382 PHE A C    1 
ATOM   2883 O  O    . PHE A 1 382 ? 106.550 71.133  131.573 1.00 121.52 ? 382 PHE A O    1 
ATOM   2884 C  CB   . PHE A 1 382 ? 106.141 70.987  128.538 1.00 121.52 ? 382 PHE A CB   1 
ATOM   2885 C  CG   . PHE A 1 382 ? 106.507 71.622  127.227 1.00 121.52 ? 382 PHE A CG   1 
ATOM   2886 C  CD1  . PHE A 1 382 ? 105.611 72.442  126.562 1.00 121.52 ? 382 PHE A CD1  1 
ATOM   2887 C  CD2  . PHE A 1 382 ? 107.742 71.384  126.649 1.00 121.52 ? 382 PHE A CD2  1 
ATOM   2888 C  CE1  . PHE A 1 382 ? 105.945 73.024  125.356 1.00 121.52 ? 382 PHE A CE1  1 
ATOM   2889 C  CE2  . PHE A 1 382 ? 108.079 71.957  125.440 1.00 121.52 ? 382 PHE A CE2  1 
ATOM   2890 C  CZ   . PHE A 1 382 ? 107.180 72.779  124.793 1.00 121.52 ? 382 PHE A CZ   1 
ATOM   2891 N  N    . LYS A 1 383 ? 104.308 70.979  131.391 1.00 118.11 ? 383 LYS A N    1 
ATOM   2892 C  CA   . LYS A 1 383 ? 104.149 70.341  132.689 1.00 118.11 ? 383 LYS A CA   1 
ATOM   2893 C  C    . LYS A 1 383 ? 103.541 68.951  132.549 1.00 118.11 ? 383 LYS A C    1 
ATOM   2894 O  O    . LYS A 1 383 ? 104.075 67.975  133.075 1.00 118.11 ? 383 LYS A O    1 
ATOM   2895 C  CB   . LYS A 1 383 ? 103.282 71.201  133.607 1.00 118.11 ? 383 LYS A CB   1 
ATOM   2896 C  CG   . LYS A 1 383 ? 102.866 70.505  134.891 1.00 118.11 ? 383 LYS A CG   1 
ATOM   2897 C  CD   . LYS A 1 383 ? 102.068 71.431  135.794 1.00 118.11 ? 383 LYS A CD   1 
ATOM   2898 C  CE   . LYS A 1 383 ? 102.753 72.778  135.938 1.00 118.11 ? 383 LYS A CE   1 
ATOM   2899 N  NZ   . LYS A 1 383 ? 102.039 73.673  136.888 1.00 118.11 ? 383 LYS A NZ   1 
ATOM   2900 N  N    . ALA B 1 16  ? 95.887  120.443 125.936 1.00 97.25  ? 16  ALA B N    1 
ATOM   2901 C  CA   . ALA B 1 16  ? 97.279  120.044 125.765 1.00 97.25  ? 16  ALA B CA   1 
ATOM   2902 C  C    . ALA B 1 16  ? 98.047  121.075 124.948 1.00 97.25  ? 16  ALA B C    1 
ATOM   2903 O  O    . ALA B 1 16  ? 99.276  121.096 124.955 1.00 97.25  ? 16  ALA B O    1 
ATOM   2904 C  CB   . ALA B 1 16  ? 97.363  118.678 125.106 1.00 97.25  ? 16  ALA B CB   1 
ATOM   2905 N  N    . LEU B 1 17  ? 97.312  121.927 124.233 1.00 96.53  ? 17  LEU B N    1 
ATOM   2906 C  CA   . LEU B 1 17  ? 97.949  122.985 123.457 1.00 96.53  ? 17  LEU B CA   1 
ATOM   2907 C  C    . LEU B 1 17  ? 98.555  124.042 124.367 1.00 96.53  ? 17  LEU B C    1 
ATOM   2908 O  O    . LEU B 1 17  ? 99.720  124.421 124.205 1.00 96.53  ? 17  LEU B O    1 
ATOM   2909 C  CB   . LEU B 1 17  ? 96.931  123.616 122.505 1.00 96.53  ? 17  LEU B CB   1 
ATOM   2910 C  CG   . LEU B 1 17  ? 97.394  124.674 121.501 1.00 96.53  ? 17  LEU B CG   1 
ATOM   2911 C  CD1  . LEU B 1 17  ? 96.720  124.455 120.160 1.00 96.53  ? 17  LEU B CD1  1 
ATOM   2912 C  CD2  . LEU B 1 17  ? 97.090  126.075 122.015 1.00 96.53  ? 17  LEU B CD2  1 
ATOM   2913 N  N    . SER B 1 18  ? 97.785  124.520 125.340 1.00 97.67  ? 18  SER B N    1 
ATOM   2914 C  CA   . SER B 1 18  ? 98.179  125.674 126.133 1.00 97.67  ? 18  SER B CA   1 
ATOM   2915 C  C    . SER B 1 18  ? 99.041  125.325 127.338 1.00 97.67  ? 18  SER B C    1 
ATOM   2916 O  O    . SER B 1 18  ? 99.497  126.235 128.036 1.00 97.67  ? 18  SER B O    1 
ATOM   2917 C  CB   . SER B 1 18  ? 96.933  126.434 126.602 1.00 97.67  ? 18  SER B CB   1 
ATOM   2918 O  OG   . SER B 1 18  ? 97.282  127.696 127.138 1.00 97.67  ? 18  SER B OG   1 
ATOM   2919 N  N    . GLU B 1 19  ? 99.268  124.043 127.610 1.00 99.29  ? 19  GLU B N    1 
ATOM   2920 C  CA   . GLU B 1 19  ? 100.130 123.608 128.708 1.00 99.29  ? 19  GLU B CA   1 
ATOM   2921 C  C    . GLU B 1 19  ? 101.103 122.548 128.204 1.00 99.29  ? 19  GLU B C    1 
ATOM   2922 O  O    . GLU B 1 19  ? 100.944 121.356 128.495 1.00 99.29  ? 19  GLU B O    1 
ATOM   2923 C  CB   . GLU B 1 19  ? 99.299  123.060 129.869 1.00 99.29  ? 19  GLU B CB   1 
ATOM   2924 C  CG   . GLU B 1 19  ? 98.350  124.056 130.519 1.00 99.29  ? 19  GLU B CG   1 
ATOM   2925 C  CD   . GLU B 1 19  ? 99.059  125.034 131.430 1.00 99.29  ? 19  GLU B CD   1 
ATOM   2926 O  OE1  . GLU B 1 19  ? 100.077 124.650 132.038 1.00 99.29  ? 19  GLU B OE1  1 
ATOM   2927 O  OE2  . GLU B 1 19  ? 98.591  126.187 131.543 1.00 99.29  ? 19  GLU B OE2  1 
ATOM   2928 N  N    . PRO B 1 20  ? 102.128 122.943 127.442 1.00 96.65  ? 20  PRO B N    1 
ATOM   2929 C  CA   . PRO B 1 20  ? 103.086 121.951 126.936 1.00 96.65  ? 20  PRO B CA   1 
ATOM   2930 C  C    . PRO B 1 20  ? 104.067 121.423 127.973 1.00 96.65  ? 20  PRO B C    1 
ATOM   2931 O  O    . PRO B 1 20  ? 104.817 120.491 127.659 1.00 96.65  ? 20  PRO B O    1 
ATOM   2932 C  CB   . PRO B 1 20  ? 103.823 122.711 125.830 1.00 96.65  ? 20  PRO B CB   1 
ATOM   2933 C  CG   . PRO B 1 20  ? 103.724 124.123 126.231 1.00 96.65  ? 20  PRO B CG   1 
ATOM   2934 C  CD   . PRO B 1 20  ? 102.387 124.279 126.880 1.00 96.65  ? 20  PRO B CD   1 
ATOM   2935 N  N    . LEU B 1 21  ? 104.094 121.971 129.186 1.00 101.48 ? 21  LEU B N    1 
ATOM   2936 C  CA   . LEU B 1 21  ? 104.979 121.485 130.233 1.00 101.48 ? 21  LEU B CA   1 
ATOM   2937 C  C    . LEU B 1 21  ? 104.181 121.049 131.454 1.00 101.48 ? 21  LEU B C    1 
ATOM   2938 O  O    . LEU B 1 21  ? 103.028 121.442 131.647 1.00 101.48 ? 21  LEU B O    1 
ATOM   2939 C  CB   . LEU B 1 21  ? 105.997 122.546 130.653 1.00 101.48 ? 21  LEU B CB   1 
ATOM   2940 C  CG   . LEU B 1 21  ? 106.889 123.108 129.556 1.00 101.48 ? 21  LEU B CG   1 
ATOM   2941 C  CD1  . LEU B 1 21  ? 107.923 124.040 130.154 1.00 101.48 ? 21  LEU B CD1  1 
ATOM   2942 C  CD2  . LEU B 1 21  ? 107.549 121.993 128.778 1.00 101.48 ? 21  LEU B CD2  1 
ATOM   2943 N  N    . SER B 1 22  ? 104.818 120.229 132.283 1.00 107.03 ? 22  SER B N    1 
ATOM   2944 C  CA   . SER B 1 22  ? 104.249 119.777 133.545 1.00 107.03 ? 22  SER B CA   1 
ATOM   2945 C  C    . SER B 1 22  ? 104.807 120.604 134.697 1.00 107.03 ? 22  SER B C    1 
ATOM   2946 O  O    . SER B 1 22  ? 105.742 121.391 134.538 1.00 107.03 ? 22  SER B O    1 
ATOM   2947 C  CB   . SER B 1 22  ? 104.540 118.290 133.765 1.00 107.03 ? 22  SER B CB   1 
ATOM   2948 O  OG   . SER B 1 22  ? 105.882 118.093 134.171 1.00 107.03 ? 22  SER B OG   1 
ATOM   2949 N  N    . ALA B 1 23  ? 104.211 120.413 135.876 1.00 111.97 ? 23  ALA B N    1 
ATOM   2950 C  CA   . ALA B 1 23  ? 104.651 121.150 137.058 1.00 111.97 ? 23  ALA B CA   1 
ATOM   2951 C  C    . ALA B 1 23  ? 106.068 120.762 137.460 1.00 111.97 ? 23  ALA B C    1 
ATOM   2952 O  O    . ALA B 1 23  ? 106.867 121.622 137.855 1.00 111.97 ? 23  ALA B O    1 
ATOM   2953 C  CB   . ALA B 1 23  ? 103.680 120.914 138.213 1.00 111.97 ? 23  ALA B CB   1 
ATOM   2954 N  N    . ALA B 1 24  ? 106.402 119.476 137.360 1.00 109.87 ? 24  ALA B N    1 
ATOM   2955 C  CA   . ALA B 1 24  ? 107.749 119.040 137.709 1.00 109.87 ? 24  ALA B CA   1 
ATOM   2956 C  C    . ALA B 1 24  ? 108.772 119.569 136.714 1.00 109.87 ? 24  ALA B C    1 
ATOM   2957 O  O    . ALA B 1 24  ? 109.913 119.874 137.087 1.00 109.87 ? 24  ALA B O    1 
ATOM   2958 C  CB   . ALA B 1 24  ? 107.804 117.515 137.779 1.00 109.87 ? 24  ALA B CB   1 
ATOM   2959 N  N    . GLN B 1 25  ? 108.395 119.648 135.435 1.00 105.47 ? 25  GLN B N    1 
ATOM   2960 C  CA   . GLN B 1 25  ? 109.288 120.243 134.448 1.00 105.47 ? 25  GLN B CA   1 
ATOM   2961 C  C    . GLN B 1 25  ? 109.536 121.708 134.761 1.00 105.47 ? 25  GLN B C    1 
ATOM   2962 O  O    . GLN B 1 25  ? 110.664 122.198 134.636 1.00 105.47 ? 25  GLN B O    1 
ATOM   2963 C  CB   . GLN B 1 25  ? 108.710 120.081 133.045 1.00 105.47 ? 25  GLN B CB   1 
ATOM   2964 C  CG   . GLN B 1 25  ? 109.334 118.951 132.251 1.00 105.47 ? 25  GLN B CG   1 
ATOM   2965 C  CD   . GLN B 1 25  ? 108.736 118.814 130.874 1.00 105.47 ? 25  GLN B CD   1 
ATOM   2966 O  OE1  . GLN B 1 25  ? 107.648 119.317 130.610 1.00 105.47 ? 25  GLN B OE1  1 
ATOM   2967 N  NE2  . GLN B 1 25  ? 109.446 118.129 129.984 1.00 105.47 ? 25  GLN B NE2  1 
ATOM   2968 N  N    . LEU B 1 26  ? 108.494 122.418 135.195 1.00 109.72 ? 26  LEU B N    1 
ATOM   2969 C  CA   . LEU B 1 26  ? 108.677 123.796 135.632 1.00 109.72 ? 26  LEU B CA   1 
ATOM   2970 C  C    . LEU B 1 26  ? 109.589 123.866 136.848 1.00 109.72 ? 26  LEU B C    1 
ATOM   2971 O  O    . LEU B 1 26  ? 110.376 124.807 136.992 1.00 109.72 ? 26  LEU B O    1 
ATOM   2972 C  CB   . LEU B 1 26  ? 107.319 124.424 135.936 1.00 109.72 ? 26  LEU B CB   1 
ATOM   2973 C  CG   . LEU B 1 26  ? 106.466 124.712 134.705 1.00 109.72 ? 26  LEU B CG   1 
ATOM   2974 C  CD1  . LEU B 1 26  ? 104.995 124.684 135.059 1.00 109.72 ? 26  LEU B CD1  1 
ATOM   2975 C  CD2  . LEU B 1 26  ? 106.841 126.041 134.101 1.00 109.72 ? 26  LEU B CD2  1 
ATOM   2976 N  N    . ARG B 1 27  ? 109.516 122.860 137.725 1.00 113.29 ? 27  ARG B N    1 
ATOM   2977 C  CA   . ARG B 1 27  ? 110.393 122.844 138.890 1.00 113.29 ? 27  ARG B CA   1 
ATOM   2978 C  C    . ARG B 1 27  ? 111.855 122.669 138.490 1.00 113.29 ? 27  ARG B C    1 
ATOM   2979 O  O    . ARG B 1 27  ? 112.726 123.399 138.982 1.00 113.29 ? 27  ARG B O    1 
ATOM   2980 C  CB   . ARG B 1 27  ? 109.960 121.746 139.860 1.00 113.29 ? 27  ARG B CB   1 
ATOM   2981 C  CG   . ARG B 1 27  ? 108.842 122.182 140.786 1.00 113.29 ? 27  ARG B CG   1 
ATOM   2982 C  CD   . ARG B 1 27  ? 109.391 123.031 141.925 1.00 113.29 ? 27  ARG B CD   1 
ATOM   2983 N  NE   . ARG B 1 27  ? 108.329 123.668 142.695 1.00 113.29 ? 27  ARG B NE   1 
ATOM   2984 C  CZ   . ARG B 1 27  ? 108.539 124.493 143.715 1.00 113.29 ? 27  ARG B CZ   1 
ATOM   2985 N  NH1  . ARG B 1 27  ? 109.775 124.782 144.095 1.00 113.29 ? 27  ARG B NH1  1 
ATOM   2986 N  NH2  . ARG B 1 27  ? 107.513 125.030 144.359 1.00 113.29 ? 27  ARG B NH2  1 
ATOM   2987 N  N    . ARG B 1 28  ? 112.151 121.718 137.594 1.00 108.81 ? 28  ARG B N    1 
ATOM   2988 C  CA   . ARG B 1 28  ? 113.541 121.599 137.156 1.00 108.81 ? 28  ARG B CA   1 
ATOM   2989 C  C    . ARG B 1 28  ? 113.994 122.823 136.368 1.00 108.81 ? 28  ARG B C    1 
ATOM   2990 O  O    . ARG B 1 28  ? 115.174 123.187 136.434 1.00 108.81 ? 28  ARG B O    1 
ATOM   2991 C  CB   . ARG B 1 28  ? 113.823 120.335 136.329 1.00 108.81 ? 28  ARG B CB   1 
ATOM   2992 C  CG   . ARG B 1 28  ? 113.699 119.034 137.122 1.00 108.81 ? 28  ARG B CG   1 
ATOM   2993 C  CD   . ARG B 1 28  ? 114.014 117.771 136.356 1.00 108.81 ? 28  ARG B CD   1 
ATOM   2994 N  NE   . ARG B 1 28  ? 113.798 116.587 137.182 1.00 108.81 ? 28  ARG B NE   1 
ATOM   2995 C  CZ   . ARG B 1 28  ? 113.897 115.354 136.686 1.00 108.81 ? 28  ARG B CZ   1 
ATOM   2996 N  NH1  . ARG B 1 28  ? 114.201 115.188 135.406 1.00 108.81 ? 28  ARG B NH1  1 
ATOM   2997 N  NH2  . ARG B 1 28  ? 113.696 114.288 137.442 1.00 108.81 ? 28  ARG B NH2  1 
ATOM   2998 N  N    . LEU B 1 29  ? 113.092 123.467 135.623 1.00 104.49 ? 29  LEU B N    1 
ATOM   2999 C  CA   . LEU B 1 29  ? 113.467 124.695 134.923 1.00 104.49 ? 29  LEU B CA   1 
ATOM   3000 C  C    . LEU B 1 29  ? 113.806 125.803 135.907 1.00 104.49 ? 29  LEU B C    1 
ATOM   3001 O  O    . LEU B 1 29  ? 114.737 126.583 135.674 1.00 104.49 ? 29  LEU B O    1 
ATOM   3002 C  CB   . LEU B 1 29  ? 112.347 125.129 133.980 1.00 104.49 ? 29  LEU B CB   1 
ATOM   3003 C  CG   . LEU B 1 29  ? 112.624 126.304 133.040 1.00 104.49 ? 29  LEU B CG   1 
ATOM   3004 C  CD1  . LEU B 1 29  ? 112.068 126.013 131.667 1.00 104.49 ? 29  LEU B CD1  1 
ATOM   3005 C  CD2  . LEU B 1 29  ? 111.988 127.566 133.583 1.00 104.49 ? 29  LEU B CD2  1 
ATOM   3006 N  N    . GLU B 1 30  ? 113.061 125.893 137.008 1.00 112.82 ? 30  GLU B N    1 
ATOM   3007 C  CA   . GLU B 1 30  ? 113.408 126.842 138.056 1.00 112.82 ? 30  GLU B CA   1 
ATOM   3008 C  C    . GLU B 1 30  ? 114.739 126.486 138.703 1.00 112.82 ? 30  GLU B C    1 
ATOM   3009 O  O    . GLU B 1 30  ? 115.489 127.381 139.109 1.00 112.82 ? 30  GLU B O    1 
ATOM   3010 C  CB   . GLU B 1 30  ? 112.293 126.896 139.099 1.00 112.82 ? 30  GLU B CB   1 
ATOM   3011 C  CG   . GLU B 1 30  ? 112.485 127.952 140.172 1.00 112.82 ? 30  GLU B CG   1 
ATOM   3012 C  CD   . GLU B 1 30  ? 112.817 129.315 139.599 1.00 112.82 ? 30  GLU B CD   1 
ATOM   3013 O  OE1  . GLU B 1 30  ? 113.815 129.918 140.050 1.00 112.82 ? 30  GLU B OE1  1 
ATOM   3014 O  OE2  . GLU B 1 30  ? 112.085 129.785 138.705 1.00 112.82 ? 30  GLU B OE2  1 
ATOM   3015 N  N    . GLU B 1 31  ? 115.054 125.194 138.800 1.00 113.41 ? 31  GLU B N    1 
ATOM   3016 C  CA   . GLU B 1 31  ? 116.315 124.774 139.399 1.00 113.41 ? 31  GLU B CA   1 
ATOM   3017 C  C    . GLU B 1 31  ? 117.519 125.042 138.501 1.00 113.41 ? 31  GLU B C    1 
ATOM   3018 O  O    . GLU B 1 31  ? 118.632 125.196 139.015 1.00 113.41 ? 31  GLU B O    1 
ATOM   3019 C  CB   . GLU B 1 31  ? 116.225 123.286 139.764 1.00 113.41 ? 31  GLU B CB   1 
ATOM   3020 C  CG   . GLU B 1 31  ? 117.363 122.713 140.616 1.00 113.41 ? 31  GLU B CG   1 
ATOM   3021 C  CD   . GLU B 1 31  ? 118.581 122.297 139.808 1.00 113.41 ? 31  GLU B CD   1 
ATOM   3022 O  OE1  . GLU B 1 31  ? 118.416 121.927 138.627 1.00 113.41 ? 31  GLU B OE1  1 
ATOM   3023 O  OE2  . GLU B 1 31  ? 119.702 122.341 140.358 1.00 113.41 ? 31  GLU B OE2  1 
ATOM   3024 N  N    . HIS B 1 32  ? 117.321 125.145 137.187 1.00 107.93 ? 32  HIS B N    1 
ATOM   3025 C  CA   . HIS B 1 32  ? 118.439 125.228 136.252 1.00 107.93 ? 32  HIS B CA   1 
ATOM   3026 C  C    . HIS B 1 32  ? 119.211 126.533 136.408 1.00 107.93 ? 32  HIS B C    1 
ATOM   3027 O  O    . HIS B 1 32  ? 118.656 127.577 136.757 1.00 107.93 ? 32  HIS B O    1 
ATOM   3028 C  CB   . HIS B 1 32  ? 117.944 125.103 134.813 1.00 107.93 ? 32  HIS B CB   1 
ATOM   3029 C  CG   . HIS B 1 32  ? 119.043 124.960 133.805 1.00 107.93 ? 32  HIS B CG   1 
ATOM   3030 N  ND1  . HIS B 1 32  ? 119.585 126.037 133.138 1.00 107.93 ? 32  HIS B ND1  1 
ATOM   3031 C  CD2  . HIS B 1 32  ? 119.695 123.867 133.344 1.00 107.93 ? 32  HIS B CD2  1 
ATOM   3032 C  CE1  . HIS B 1 32  ? 120.528 125.614 132.315 1.00 107.93 ? 32  HIS B CE1  1 
ATOM   3033 N  NE2  . HIS B 1 32  ? 120.613 124.300 132.419 1.00 107.93 ? 32  HIS B NE2  1 
ATOM   3034 N  N    . ARG B 1 33  ? 120.514 126.458 136.139 1.00 114.91 ? 33  ARG B N    1 
ATOM   3035 C  CA   . ARG B 1 33  ? 121.399 127.611 136.156 1.00 114.91 ? 33  ARG B CA   1 
ATOM   3036 C  C    . ARG B 1 33  ? 122.219 127.632 134.876 1.00 114.91 ? 33  ARG B C    1 
ATOM   3037 O  O    . ARG B 1 33  ? 122.678 126.587 134.403 1.00 114.91 ? 33  ARG B O    1 
ATOM   3038 C  CB   . ARG B 1 33  ? 122.321 127.585 137.382 1.00 114.91 ? 33  ARG B CB   1 
ATOM   3039 C  CG   . ARG B 1 33  ? 123.022 128.905 137.685 1.00 114.91 ? 33  ARG B CG   1 
ATOM   3040 C  CD   . ARG B 1 33  ? 122.118 130.110 137.441 1.00 114.91 ? 33  ARG B CD   1 
ATOM   3041 N  NE   . ARG B 1 33  ? 121.149 130.309 138.515 1.00 114.91 ? 33  ARG B NE   1 
ATOM   3042 C  CZ   . ARG B 1 33  ? 120.314 131.339 138.585 1.00 114.91 ? 33  ARG B CZ   1 
ATOM   3043 N  NH1  . ARG B 1 33  ? 120.328 132.272 137.643 1.00 114.91 ? 33  ARG B NH1  1 
ATOM   3044 N  NH2  . ARG B 1 33  ? 119.464 131.442 139.598 1.00 114.91 ? 33  ARG B NH2  1 
ATOM   3045 N  N    . TYR B 1 34  ? 122.401 128.826 134.317 1.00 112.70 ? 34  TYR B N    1 
ATOM   3046 C  CA   . TYR B 1 34  ? 123.096 128.979 133.046 1.00 112.70 ? 34  TYR B CA   1 
ATOM   3047 C  C    . TYR B 1 34  ? 124.605 129.019 133.248 1.00 112.70 ? 34  TYR B C    1 
ATOM   3048 O  O    . TYR B 1 34  ? 125.103 129.619 134.204 1.00 112.70 ? 34  TYR B O    1 
ATOM   3049 C  CB   . TYR B 1 34  ? 122.626 130.252 132.340 1.00 112.70 ? 34  TYR B CB   1 
ATOM   3050 C  CG   . TYR B 1 34  ? 123.284 130.497 131.002 1.00 112.70 ? 34  TYR B CG   1 
ATOM   3051 C  CD1  . TYR B 1 34  ? 123.327 129.503 130.032 1.00 112.70 ? 34  TYR B CD1  1 
ATOM   3052 C  CD2  . TYR B 1 34  ? 123.853 131.725 130.703 1.00 112.70 ? 34  TYR B CD2  1 
ATOM   3053 C  CE1  . TYR B 1 34  ? 123.928 129.723 128.808 1.00 112.70 ? 34  TYR B CE1  1 
ATOM   3054 C  CE2  . TYR B 1 34  ? 124.458 131.956 129.485 1.00 112.70 ? 34  TYR B CE2  1 
ATOM   3055 C  CZ   . TYR B 1 34  ? 124.490 130.953 128.540 1.00 112.70 ? 34  TYR B CZ   1 
ATOM   3056 O  OH   . TYR B 1 34  ? 125.090 131.182 127.325 1.00 112.70 ? 34  TYR B OH   1 
ATOM   3057 N  N    . SER B 1 35  ? 125.329 128.371 132.337 1.00 112.14 ? 35  SER B N    1 
ATOM   3058 C  CA   . SER B 1 35  ? 126.782 128.341 132.390 1.00 112.14 ? 35  SER B CA   1 
ATOM   3059 C  C    . SER B 1 35  ? 127.337 128.264 130.974 1.00 112.14 ? 35  SER B C    1 
ATOM   3060 O  O    . SER B 1 35  ? 126.673 127.766 130.061 1.00 112.14 ? 35  SER B O    1 
ATOM   3061 C  CB   . SER B 1 35  ? 127.292 127.161 133.221 1.00 112.14 ? 35  SER B CB   1 
ATOM   3062 O  OG   . SER B 1 35  ? 126.922 127.301 134.584 1.00 112.14 ? 35  SER B OG   1 
ATOM   3063 N  N    . ALA B 1 36  ? 128.561 128.761 130.803 1.00 112.23 ? 36  ALA B N    1 
ATOM   3064 C  CA   . ALA B 1 36  ? 129.227 128.752 129.510 1.00 112.23 ? 36  ALA B CA   1 
ATOM   3065 C  C    . ALA B 1 36  ? 130.732 128.800 129.728 1.00 112.23 ? 36  ALA B C    1 
ATOM   3066 O  O    . ALA B 1 36  ? 131.216 129.406 130.685 1.00 112.23 ? 36  ALA B O    1 
ATOM   3067 C  CB   . ALA B 1 36  ? 128.779 129.927 128.634 1.00 112.23 ? 36  ALA B CB   1 
ATOM   3068 N  N    . ALA B 1 37  ? 131.469 128.150 128.831 1.00 112.84 ? 37  ALA B N    1 
ATOM   3069 C  CA   . ALA B 1 37  ? 132.921 128.040 128.938 1.00 112.84 ? 37  ALA B CA   1 
ATOM   3070 C  C    . ALA B 1 37  ? 133.582 128.270 127.583 1.00 112.84 ? 37  ALA B C    1 
ATOM   3071 O  O    . ALA B 1 37  ? 134.441 127.505 127.146 1.00 112.84 ? 37  ALA B O    1 
ATOM   3072 C  CB   . ALA B 1 37  ? 133.318 126.682 129.513 1.00 112.84 ? 37  ALA B CB   1 
ATOM   3073 N  N    . GLY B 1 38  ? 133.181 129.336 126.893 1.00 110.53 ? 38  GLY B N    1 
ATOM   3074 C  CA   . GLY B 1 38  ? 133.684 129.559 125.550 1.00 110.53 ? 38  GLY B CA   1 
ATOM   3075 C  C    . GLY B 1 38  ? 134.432 130.853 125.308 1.00 110.53 ? 38  GLY B C    1 
ATOM   3076 O  O    . GLY B 1 38  ? 133.867 131.944 125.438 1.00 110.53 ? 38  GLY B O    1 
ATOM   3077 N  N    . VAL B 1 39  ? 135.709 130.741 124.943 1.00 112.24 ? 39  VAL B N    1 
ATOM   3078 C  CA   . VAL B 1 39  ? 136.546 131.877 124.572 1.00 112.24 ? 39  VAL B CA   1 
ATOM   3079 C  C    . VAL B 1 39  ? 137.295 131.510 123.300 1.00 112.24 ? 39  VAL B C    1 
ATOM   3080 O  O    . VAL B 1 39  ? 137.920 130.446 123.230 1.00 112.24 ? 39  VAL B O    1 
ATOM   3081 C  CB   . VAL B 1 39  ? 137.536 132.253 125.693 1.00 112.24 ? 39  VAL B CB   1 
ATOM   3082 C  CG1  . VAL B 1 39  ? 138.562 133.258 125.191 1.00 112.24 ? 39  VAL B CG1  1 
ATOM   3083 C  CG2  . VAL B 1 39  ? 136.802 132.808 126.902 1.00 112.24 ? 39  VAL B CG2  1 
ATOM   3084 N  N    . SER B 1 40  ? 137.242 132.386 122.302 1.00 112.95 ? 40  SER B N    1 
ATOM   3085 C  CA   . SER B 1 40  ? 137.960 132.168 121.049 1.00 112.95 ? 40  SER B CA   1 
ATOM   3086 C  C    . SER B 1 40  ? 138.580 133.497 120.628 1.00 112.95 ? 40  SER B C    1 
ATOM   3087 O  O    . SER B 1 40  ? 138.682 134.440 121.420 1.00 112.95 ? 40  SER B O    1 
ATOM   3088 C  CB   . SER B 1 40  ? 137.036 131.572 119.978 1.00 112.95 ? 40  SER B CB   1 
ATOM   3089 O  OG   . SER B 1 40  ? 136.140 132.535 119.467 1.00 112.95 ? 40  SER B OG   1 
ATOM   3090 N  N    . LEU B 1 41  ? 139.008 133.581 119.368 1.00 115.43 ? 41  LEU B N    1 
ATOM   3091 C  CA   . LEU B 1 41  ? 139.815 134.701 118.899 1.00 115.43 ? 41  LEU B CA   1 
ATOM   3092 C  C    . LEU B 1 41  ? 139.033 136.002 118.742 1.00 115.43 ? 41  LEU B C    1 
ATOM   3093 O  O    . LEU B 1 41  ? 139.508 137.058 119.172 1.00 115.43 ? 41  LEU B O    1 
ATOM   3094 C  CB   . LEU B 1 41  ? 140.473 134.344 117.565 1.00 115.43 ? 41  LEU B CB   1 
ATOM   3095 C  CG   . LEU B 1 41  ? 141.394 135.414 116.975 1.00 115.43 ? 41  LEU B CG   1 
ATOM   3096 C  CD1  . LEU B 1 41  ? 142.637 135.589 117.836 1.00 115.43 ? 41  LEU B CD1  1 
ATOM   3097 C  CD2  . LEU B 1 41  ? 141.778 135.076 115.541 1.00 115.43 ? 41  LEU B CD2  1 
ATOM   3098 N  N    . LEU B 1 42  ? 137.846 135.964 118.145 1.00 111.48 ? 42  LEU B N    1 
ATOM   3099 C  CA   . LEU B 1 42  ? 137.201 137.188 117.682 1.00 111.48 ? 42  LEU B CA   1 
ATOM   3100 C  C    . LEU B 1 42  ? 136.356 137.887 118.739 1.00 111.48 ? 42  LEU B C    1 
ATOM   3101 O  O    . LEU B 1 42  ? 135.872 138.994 118.481 1.00 111.48 ? 42  LEU B O    1 
ATOM   3102 C  CB   . LEU B 1 42  ? 136.327 136.899 116.454 1.00 111.48 ? 42  LEU B CB   1 
ATOM   3103 C  CG   . LEU B 1 42  ? 136.983 136.880 115.065 1.00 111.48 ? 42  LEU B CG   1 
ATOM   3104 C  CD1  . LEU B 1 42  ? 137.536 138.259 114.728 1.00 111.48 ? 42  LEU B CD1  1 
ATOM   3105 C  CD2  . LEU B 1 42  ? 138.061 135.810 114.909 1.00 111.48 ? 42  LEU B CD2  1 
ATOM   3106 N  N    . GLU B 1 43  ? 136.162 137.287 119.911 1.00 115.62 ? 43  GLU B N    1 
ATOM   3107 C  CA   . GLU B 1 43  ? 135.354 137.955 120.933 1.00 115.62 ? 43  GLU B CA   1 
ATOM   3108 C  C    . GLU B 1 43  ? 136.058 139.133 121.595 1.00 115.62 ? 43  GLU B C    1 
ATOM   3109 O  O    . GLU B 1 43  ? 135.419 140.197 121.724 1.00 115.62 ? 43  GLU B O    1 
ATOM   3110 C  CB   . GLU B 1 43  ? 134.840 136.950 121.977 1.00 115.62 ? 43  GLU B CB   1 
ATOM   3111 C  CG   . GLU B 1 43  ? 133.814 135.883 121.543 1.00 115.62 ? 43  GLU B CG   1 
ATOM   3112 C  CD   . GLU B 1 43  ? 133.425 134.902 122.619 1.00 115.62 ? 43  GLU B CD   1 
ATOM   3113 O  OE1  . GLU B 1 43  ? 134.068 134.886 123.688 1.00 115.62 ? 43  GLU B OE1  1 
ATOM   3114 O  OE2  . GLU B 1 43  ? 132.452 134.159 122.405 1.00 115.62 ? 43  GLU B OE2  1 
ATOM   3115 N  N    . PRO B 1 44  ? 137.316 139.049 122.052 1.00 118.77 ? 44  PRO B N    1 
ATOM   3116 C  CA   . PRO B 1 44  ? 137.917 140.171 122.812 1.00 118.77 ? 44  PRO B CA   1 
ATOM   3117 C  C    . PRO B 1 44  ? 137.925 141.499 122.058 1.00 118.77 ? 44  PRO B C    1 
ATOM   3118 O  O    . PRO B 1 44  ? 137.770 142.547 122.700 1.00 118.77 ? 44  PRO B O    1 
ATOM   3119 C  CB   . PRO B 1 44  ? 139.340 139.680 123.107 1.00 118.77 ? 44  PRO B CB   1 
ATOM   3120 C  CG   . PRO B 1 44  ? 139.193 138.230 123.193 1.00 118.77 ? 44  PRO B CG   1 
ATOM   3121 C  CD   . PRO B 1 44  ? 138.216 137.872 122.114 1.00 118.77 ? 44  PRO B CD   1 
ATOM   3122 N  N    . PRO B 1 45  ? 138.107 141.531 120.726 1.00 118.09 ? 45  PRO B N    1 
ATOM   3123 C  CA   . PRO B 1 45  ? 137.886 142.821 120.047 1.00 118.09 ? 45  PRO B CA   1 
ATOM   3124 C  C    . PRO B 1 45  ? 136.434 143.276 120.041 1.00 118.09 ? 45  PRO B C    1 
ATOM   3125 O  O    . PRO B 1 45  ? 136.182 144.470 119.841 1.00 118.09 ? 45  PRO B O    1 
ATOM   3126 C  CB   . PRO B 1 45  ? 138.402 142.567 118.622 1.00 118.09 ? 45  PRO B CB   1 
ATOM   3127 C  CG   . PRO B 1 45  ? 138.414 141.110 118.470 1.00 118.09 ? 45  PRO B CG   1 
ATOM   3128 C  CD   . PRO B 1 45  ? 138.787 140.595 119.812 1.00 118.09 ? 45  PRO B CD   1 
ATOM   3129 N  N    . LEU B 1 46  ? 135.474 142.376 120.257 1.00 119.13 ? 46  LEU B N    1 
ATOM   3130 C  CA   . LEU B 1 46  ? 134.066 142.743 120.148 1.00 119.13 ? 46  LEU B CA   1 
ATOM   3131 C  C    . LEU B 1 46  ? 133.391 142.991 121.491 1.00 119.13 ? 46  LEU B C    1 
ATOM   3132 O  O    . LEU B 1 46  ? 132.303 143.578 121.519 1.00 119.13 ? 46  LEU B O    1 
ATOM   3133 C  CB   . LEU B 1 46  ? 133.289 141.657 119.397 1.00 119.13 ? 46  LEU B CB   1 
ATOM   3134 C  CG   . LEU B 1 46  ? 133.565 141.520 117.897 1.00 119.13 ? 46  LEU B CG   1 
ATOM   3135 C  CD1  . LEU B 1 46  ? 132.787 140.352 117.324 1.00 119.13 ? 46  LEU B CD1  1 
ATOM   3136 C  CD2  . LEU B 1 46  ? 133.221 142.802 117.161 1.00 119.13 ? 46  LEU B CD2  1 
ATOM   3137 N  N    . GLN B 1 47  ? 133.995 142.543 122.594 1.00 122.12 ? 47  GLN B N    1 
ATOM   3138 C  CA   . GLN B 1 47  ? 133.388 142.734 123.910 1.00 122.12 ? 47  GLN B CA   1 
ATOM   3139 C  C    . GLN B 1 47  ? 133.259 144.214 124.246 1.00 122.12 ? 47  GLN B C    1 
ATOM   3140 O  O    . GLN B 1 47  ? 132.210 144.665 124.723 1.00 122.12 ? 47  GLN B O    1 
ATOM   3141 C  CB   . GLN B 1 47  ? 134.222 142.016 124.974 1.00 122.12 ? 47  GLN B CB   1 
ATOM   3142 C  CG   . GLN B 1 47  ? 134.105 140.468 125.110 1.00 122.12 ? 47  GLN B CG   1 
ATOM   3143 C  CD   . GLN B 1 47  ? 132.692 139.854 125.133 1.00 122.12 ? 47  GLN B CD   1 
ATOM   3144 O  OE1  . GLN B 1 47  ? 131.669 140.532 125.063 1.00 122.12 ? 47  GLN B OE1  1 
ATOM   3145 N  NE2  . GLN B 1 47  ? 132.654 138.529 125.237 1.00 122.12 ? 47  GLN B NE2  1 
ATOM   3146 N  N    . LEU B 1 48  ? 134.321 144.984 123.993 1.00 127.81 ? 48  LEU B N    1 
ATOM   3147 C  CA   . LEU B 1 48  ? 134.289 146.419 124.248 1.00 127.81 ? 48  LEU B CA   1 
ATOM   3148 C  C    . LEU B 1 48  ? 133.248 147.104 123.375 1.00 127.81 ? 48  LEU B C    1 
ATOM   3149 O  O    . LEU B 1 48  ? 132.534 147.999 123.837 1.00 127.81 ? 48  LEU B O    1 
ATOM   3150 C  CB   . LEU B 1 48  ? 135.670 147.030 124.010 1.00 127.81 ? 48  LEU B CB   1 
ATOM   3151 C  CG   . LEU B 1 48  ? 136.700 147.053 125.146 1.00 127.81 ? 48  LEU B CG   1 
ATOM   3152 C  CD1  . LEU B 1 48  ? 136.183 147.865 126.329 1.00 127.81 ? 48  LEU B CD1  1 
ATOM   3153 C  CD2  . LEU B 1 48  ? 137.119 145.657 125.581 1.00 127.81 ? 48  LEU B CD2  1 
ATOM   3154 N  N    . TYR B 1 49  ? 133.157 146.691 122.108 1.00 126.01 ? 49  TYR B N    1 
ATOM   3155 C  CA   . TYR B 1 49  ? 132.184 147.283 121.194 1.00 126.01 ? 49  TYR B CA   1 
ATOM   3156 C  C    . TYR B 1 49  ? 130.763 147.003 121.662 1.00 126.01 ? 49  TYR B C    1 
ATOM   3157 O  O    . TYR B 1 49  ? 129.904 147.895 121.652 1.00 126.01 ? 49  TYR B O    1 
ATOM   3158 C  CB   . TYR B 1 49  ? 132.422 146.730 119.787 1.00 126.01 ? 49  TYR B CB   1 
ATOM   3159 C  CG   . TYR B 1 49  ? 131.782 147.507 118.659 1.00 126.01 ? 49  TYR B CG   1 
ATOM   3160 C  CD1  . TYR B 1 49  ? 132.397 148.640 118.146 1.00 126.01 ? 49  TYR B CD1  1 
ATOM   3161 C  CD2  . TYR B 1 49  ? 130.589 147.090 118.084 1.00 126.01 ? 49  TYR B CD2  1 
ATOM   3162 C  CE1  . TYR B 1 49  ? 131.834 149.352 117.106 1.00 126.01 ? 49  TYR B CE1  1 
ATOM   3163 C  CE2  . TYR B 1 49  ? 130.020 147.797 117.040 1.00 126.01 ? 49  TYR B CE2  1 
ATOM   3164 C  CZ   . TYR B 1 49  ? 130.647 148.929 116.557 1.00 126.01 ? 49  TYR B CZ   1 
ATOM   3165 O  OH   . TYR B 1 49  ? 130.092 149.641 115.520 1.00 126.01 ? 49  TYR B OH   1 
ATOM   3166 N  N    . TRP B 1 50  ? 130.505 145.770 122.106 1.00 117.80 ? 50  TRP B N    1 
ATOM   3167 C  CA   . TRP B 1 50  ? 129.180 145.409 122.597 1.00 117.80 ? 50  TRP B CA   1 
ATOM   3168 C  C    . TRP B 1 50  ? 128.823 146.190 123.855 1.00 117.80 ? 50  TRP B C    1 
ATOM   3169 O  O    . TRP B 1 50  ? 127.697 146.678 123.988 1.00 117.80 ? 50  TRP B O    1 
ATOM   3170 C  CB   . TRP B 1 50  ? 129.114 143.910 122.863 1.00 117.80 ? 50  TRP B CB   1 
ATOM   3171 C  CG   . TRP B 1 50  ? 129.084 143.096 121.615 1.00 117.80 ? 50  TRP B CG   1 
ATOM   3172 C  CD1  . TRP B 1 50  ? 128.530 143.446 120.421 1.00 117.80 ? 50  TRP B CD1  1 
ATOM   3173 C  CD2  . TRP B 1 50  ? 129.654 141.800 121.431 1.00 117.80 ? 50  TRP B CD2  1 
ATOM   3174 N  NE1  . TRP B 1 50  ? 128.709 142.440 119.505 1.00 117.80 ? 50  TRP B NE1  1 
ATOM   3175 C  CE2  . TRP B 1 50  ? 129.396 141.417 120.105 1.00 117.80 ? 50  TRP B CE2  1 
ATOM   3176 C  CE3  . TRP B 1 50  ? 130.344 140.922 122.263 1.00 117.80 ? 50  TRP B CE3  1 
ATOM   3177 C  CZ2  . TRP B 1 50  ? 129.812 140.196 119.590 1.00 117.80 ? 50  TRP B CZ2  1 
ATOM   3178 C  CZ3  . TRP B 1 50  ? 130.756 139.714 121.753 1.00 117.80 ? 50  TRP B CZ3  1 
ATOM   3179 C  CH2  . TRP B 1 50  ? 130.489 139.360 120.429 1.00 117.80 ? 50  TRP B CH2  1 
ATOM   3180 N  N    . THR B 1 51  ? 129.778 146.346 124.776 1.00 123.01 ? 51  THR B N    1 
ATOM   3181 C  CA   . THR B 1 51  ? 129.515 147.136 125.975 1.00 123.01 ? 51  THR B CA   1 
ATOM   3182 C  C    . THR B 1 51  ? 129.255 148.599 125.628 1.00 123.01 ? 51  THR B C    1 
ATOM   3183 O  O    . THR B 1 51  ? 128.390 149.247 126.239 1.00 123.01 ? 51  THR B O    1 
ATOM   3184 C  CB   . THR B 1 51  ? 130.691 147.020 126.944 1.00 123.01 ? 51  THR B CB   1 
ATOM   3185 O  OG1  . THR B 1 51  ? 131.126 145.656 127.005 1.00 123.01 ? 51  THR B OG1  1 
ATOM   3186 C  CG2  . THR B 1 51  ? 130.277 147.471 128.332 1.00 123.01 ? 51  THR B CG2  1 
ATOM   3187 N  N    . TRP B 1 52  ? 130.008 149.125 124.649 1.00 128.22 ? 52  TRP B N    1 
ATOM   3188 C  CA   . TRP B 1 52  ? 129.862 150.515 124.233 1.00 128.22 ? 52  TRP B CA   1 
ATOM   3189 C  C    . TRP B 1 52  ? 128.496 150.772 123.617 1.00 128.22 ? 52  TRP B C    1 
ATOM   3190 O  O    . TRP B 1 52  ? 127.893 151.827 123.844 1.00 128.22 ? 52  TRP B O    1 
ATOM   3191 C  CB   . TRP B 1 52  ? 130.966 150.893 123.248 1.00 128.22 ? 52  TRP B CB   1 
ATOM   3192 C  CG   . TRP B 1 52  ? 130.787 152.263 122.673 1.00 128.22 ? 52  TRP B CG   1 
ATOM   3193 C  CD1  . TRP B 1 52  ? 130.541 153.414 123.359 1.00 128.22 ? 52  TRP B CD1  1 
ATOM   3194 C  CD2  . TRP B 1 52  ? 130.834 152.627 121.289 1.00 128.22 ? 52  TRP B CD2  1 
ATOM   3195 N  NE1  . TRP B 1 52  ? 130.431 154.472 122.493 1.00 128.22 ? 52  TRP B NE1  1 
ATOM   3196 C  CE2  . TRP B 1 52  ? 130.609 154.013 121.213 1.00 128.22 ? 52  TRP B CE2  1 
ATOM   3197 C  CE3  . TRP B 1 52  ? 131.047 151.913 120.105 1.00 128.22 ? 52  TRP B CE3  1 
ATOM   3198 C  CZ2  . TRP B 1 52  ? 130.593 154.701 120.004 1.00 128.22 ? 52  TRP B CZ2  1 
ATOM   3199 C  CZ3  . TRP B 1 52  ? 131.030 152.598 118.905 1.00 128.22 ? 52  TRP B CZ3  1 
ATOM   3200 C  CH2  . TRP B 1 52  ? 130.803 153.977 118.862 1.00 128.22 ? 52  TRP B CH2  1 
ATOM   3201 N  N    . LEU B 1 53  ? 127.996 149.834 122.816 1.00 122.77 ? 53  LEU B N    1 
ATOM   3202 C  CA   . LEU B 1 53  ? 126.607 149.947 122.390 1.00 122.77 ? 53  LEU B CA   1 
ATOM   3203 C  C    . LEU B 1 53  ? 125.635 149.656 123.526 1.00 122.77 ? 53  LEU B C    1 
ATOM   3204 O  O    . LEU B 1 53  ? 124.468 150.053 123.441 1.00 122.77 ? 53  LEU B O    1 
ATOM   3205 C  CB   . LEU B 1 53  ? 126.318 149.030 121.197 1.00 122.77 ? 53  LEU B CB   1 
ATOM   3206 C  CG   . LEU B 1 53  ? 126.714 149.517 119.795 1.00 122.77 ? 53  LEU B CG   1 
ATOM   3207 C  CD1  . LEU B 1 53  ? 128.207 149.531 119.548 1.00 122.77 ? 53  LEU B CD1  1 
ATOM   3208 C  CD2  . LEU B 1 53  ? 126.013 148.682 118.732 1.00 122.77 ? 53  LEU B CD2  1 
ATOM   3209 N  N    . LEU B 1 54  ? 126.086 148.981 124.585 1.00 123.58 ? 54  LEU B N    1 
ATOM   3210 C  CA   . LEU B 1 54  ? 125.157 148.607 125.641 1.00 123.58 ? 54  LEU B CA   1 
ATOM   3211 C  C    . LEU B 1 54  ? 124.774 149.785 126.526 1.00 123.58 ? 54  LEU B C    1 
ATOM   3212 O  O    . LEU B 1 54  ? 123.596 149.905 126.887 1.00 123.58 ? 54  LEU B O    1 
ATOM   3213 C  CB   . LEU B 1 54  ? 125.744 147.463 126.477 1.00 123.58 ? 54  LEU B CB   1 
ATOM   3214 C  CG   . LEU B 1 54  ? 124.881 146.775 127.543 1.00 123.58 ? 54  LEU B CG   1 
ATOM   3215 C  CD1  . LEU B 1 54  ? 125.380 145.370 127.724 1.00 123.58 ? 54  LEU B CD1  1 
ATOM   3216 C  CD2  . LEU B 1 54  ? 124.913 147.470 128.899 1.00 123.58 ? 54  LEU B CD2  1 
ATOM   3217 N  N    . GLN B 1 55  ? 125.734 150.644 126.920 1.00 130.02 ? 55  GLN B N    1 
ATOM   3218 C  CA   . GLN B 1 55  ? 125.391 151.552 128.030 1.00 130.02 ? 55  GLN B CA   1 
ATOM   3219 C  C    . GLN B 1 55  ? 124.326 152.567 127.634 1.00 130.02 ? 55  GLN B C    1 
ATOM   3220 O  O    . GLN B 1 55  ? 123.650 153.114 128.511 1.00 130.02 ? 55  GLN B O    1 
ATOM   3221 C  CB   . GLN B 1 55  ? 126.544 152.399 128.595 1.00 130.02 ? 55  GLN B CB   1 
ATOM   3222 C  CG   . GLN B 1 55  ? 127.673 151.669 129.328 1.00 130.02 ? 55  GLN B CG   1 
ATOM   3223 C  CD   . GLN B 1 55  ? 128.773 152.548 129.777 1.00 130.02 ? 55  GLN B CD   1 
ATOM   3224 O  OE1  . GLN B 1 55  ? 128.983 153.595 129.208 1.00 130.02 ? 55  GLN B OE1  1 
ATOM   3225 N  NE2  . GLN B 1 55  ? 129.497 152.130 130.806 1.00 130.02 ? 55  GLN B NE2  1 
ATOM   3226 N  N    . TRP B 1 56  ? 124.164 152.832 126.336 1.00 135.55 ? 56  TRP B N    1 
ATOM   3227 C  CA   . TRP B 1 56  ? 123.178 153.803 125.885 1.00 135.55 ? 56  TRP B CA   1 
ATOM   3228 C  C    . TRP B 1 56  ? 121.758 153.266 125.986 1.00 135.55 ? 56  TRP B C    1 
ATOM   3229 O  O    . TRP B 1 56  ? 120.808 154.056 125.974 1.00 135.55 ? 56  TRP B O    1 
ATOM   3230 C  CB   . TRP B 1 56  ? 123.477 154.216 124.443 1.00 135.55 ? 56  TRP B CB   1 
ATOM   3231 C  CG   . TRP B 1 56  ? 124.611 155.185 124.313 1.00 135.55 ? 56  TRP B CG   1 
ATOM   3232 C  CD1  . TRP B 1 56  ? 124.977 156.143 125.213 1.00 135.55 ? 56  TRP B CD1  1 
ATOM   3233 C  CD2  . TRP B 1 56  ? 125.532 155.286 123.222 1.00 135.55 ? 56  TRP B CD2  1 
ATOM   3234 N  NE1  . TRP B 1 56  ? 126.067 156.835 124.746 1.00 135.55 ? 56  TRP B NE1  1 
ATOM   3235 C  CE2  . TRP B 1 56  ? 126.427 156.329 123.525 1.00 135.55 ? 56  TRP B CE2  1 
ATOM   3236 C  CE3  . TRP B 1 56  ? 125.684 154.597 122.015 1.00 135.55 ? 56  TRP B CE3  1 
ATOM   3237 C  CZ2  . TRP B 1 56  ? 127.461 156.699 122.669 1.00 135.55 ? 56  TRP B CZ2  1 
ATOM   3238 C  CZ3  . TRP B 1 56  ? 126.710 154.966 121.165 1.00 135.55 ? 56  TRP B CZ3  1 
ATOM   3239 C  CH2  . TRP B 1 56  ? 127.585 156.006 121.495 1.00 135.55 ? 56  TRP B CH2  1 
ATOM   3240 N  N    . ILE B 1 57  ? 121.596 151.955 126.080 1.00 133.92 ? 57  ILE B N    1 
ATOM   3241 C  CA   . ILE B 1 57  ? 120.264 151.352 126.150 1.00 133.92 ? 57  ILE B CA   1 
ATOM   3242 C  C    . ILE B 1 57  ? 119.682 151.595 127.540 1.00 133.92 ? 57  ILE B C    1 
ATOM   3243 O  O    . ILE B 1 57  ? 120.373 151.346 128.540 1.00 133.92 ? 57  ILE B O    1 
ATOM   3244 C  CB   . ILE B 1 57  ? 120.331 149.866 125.831 1.00 133.92 ? 57  ILE B CB   1 
ATOM   3245 C  CG1  . ILE B 1 57  ? 120.782 149.672 124.387 1.00 133.92 ? 57  ILE B CG1  1 
ATOM   3246 C  CG2  . ILE B 1 57  ? 118.988 149.193 126.055 1.00 133.92 ? 57  ILE B CG2  1 
ATOM   3247 C  CD1  . ILE B 1 57  ? 121.096 148.259 124.047 1.00 133.92 ? 57  ILE B CD1  1 
ATOM   3248 N  N    . PRO B 1 58  ? 118.449 152.086 127.642 1.00 134.30 ? 58  PRO B N    1 
ATOM   3249 C  CA   . PRO B 1 58  ? 117.837 152.285 128.960 1.00 134.30 ? 58  PRO B CA   1 
ATOM   3250 C  C    . PRO B 1 58  ? 117.612 150.965 129.680 1.00 134.30 ? 58  PRO B C    1 
ATOM   3251 O  O    . PRO B 1 58  ? 117.392 149.919 129.066 1.00 134.30 ? 58  PRO B O    1 
ATOM   3252 C  CB   . PRO B 1 58  ? 116.509 152.975 128.633 1.00 134.30 ? 58  PRO B CB   1 
ATOM   3253 C  CG   . PRO B 1 58  ? 116.227 152.602 127.216 1.00 134.30 ? 58  PRO B CG   1 
ATOM   3254 C  CD   . PRO B 1 58  ? 117.563 152.521 126.549 1.00 134.30 ? 58  PRO B CD   1 
ATOM   3255 N  N    . LEU B 1 59  ? 117.667 151.032 131.010 1.00 131.13 ? 59  LEU B N    1 
ATOM   3256 C  CA   . LEU B 1 59  ? 117.644 149.832 131.835 1.00 131.13 ? 59  LEU B CA   1 
ATOM   3257 C  C    . LEU B 1 59  ? 116.262 149.203 131.940 1.00 131.13 ? 59  LEU B C    1 
ATOM   3258 O  O    . LEU B 1 59  ? 116.158 148.043 132.353 1.00 131.13 ? 59  LEU B O    1 
ATOM   3259 C  CB   . LEU B 1 59  ? 118.167 150.148 133.236 1.00 131.13 ? 59  LEU B CB   1 
ATOM   3260 C  CG   . LEU B 1 59  ? 119.438 150.994 133.324 1.00 131.13 ? 59  LEU B CG   1 
ATOM   3261 C  CD1  . LEU B 1 59  ? 119.805 151.244 134.776 1.00 131.13 ? 59  LEU B CD1  1 
ATOM   3262 C  CD2  . LEU B 1 59  ? 120.591 150.335 132.585 1.00 131.13 ? 59  LEU B CD2  1 
ATOM   3263 N  N    . TRP B 1 60  ? 115.201 149.927 131.587 1.00 128.70 ? 60  TRP B N    1 
ATOM   3264 C  CA   . TRP B 1 60  ? 113.857 149.384 131.724 1.00 128.70 ? 60  TRP B CA   1 
ATOM   3265 C  C    . TRP B 1 60  ? 113.452 148.484 130.566 1.00 128.70 ? 60  TRP B C    1 
ATOM   3266 O  O    . TRP B 1 60  ? 112.384 147.867 130.627 1.00 128.70 ? 60  TRP B O    1 
ATOM   3267 C  CB   . TRP B 1 60  ? 112.839 150.515 131.874 1.00 128.70 ? 60  TRP B CB   1 
ATOM   3268 C  CG   . TRP B 1 60  ? 112.964 151.598 130.849 1.00 128.70 ? 60  TRP B CG   1 
ATOM   3269 C  CD1  . TRP B 1 60  ? 113.622 152.783 130.993 1.00 128.70 ? 60  TRP B CD1  1 
ATOM   3270 C  CD2  . TRP B 1 60  ? 112.417 151.598 129.527 1.00 128.70 ? 60  TRP B CD2  1 
ATOM   3271 N  NE1  . TRP B 1 60  ? 113.516 153.524 129.844 1.00 128.70 ? 60  TRP B NE1  1 
ATOM   3272 C  CE2  . TRP B 1 60  ? 112.783 152.817 128.927 1.00 128.70 ? 60  TRP B CE2  1 
ATOM   3273 C  CE3  . TRP B 1 60  ? 111.650 150.690 128.793 1.00 128.70 ? 60  TRP B CE3  1 
ATOM   3274 C  CZ2  . TRP B 1 60  ? 112.414 153.150 127.626 1.00 128.70 ? 60  TRP B CZ2  1 
ATOM   3275 C  CZ3  . TRP B 1 60  ? 111.286 151.021 127.505 1.00 128.70 ? 60  TRP B CZ3  1 
ATOM   3276 C  CH2  . TRP B 1 60  ? 111.667 152.241 126.934 1.00 128.70 ? 60  TRP B CH2  1 
ATOM   3277 N  N    . MET B 1 61  ? 114.266 148.394 129.518 1.00 118.28 ? 61  MET B N    1 
ATOM   3278 C  CA   . MET B 1 61  ? 113.926 147.573 128.365 1.00 118.28 ? 61  MET B CA   1 
ATOM   3279 C  C    . MET B 1 61  ? 114.118 146.100 128.697 1.00 118.28 ? 61  MET B C    1 
ATOM   3280 O  O    . MET B 1 61  ? 115.159 145.704 129.228 1.00 118.28 ? 61  MET B O    1 
ATOM   3281 C  CB   . MET B 1 61  ? 114.785 147.973 127.166 1.00 118.28 ? 61  MET B CB   1 
ATOM   3282 C  CG   . MET B 1 61  ? 114.333 147.387 125.844 1.00 118.28 ? 61  MET B CG   1 
ATOM   3283 S  SD   . MET B 1 61  ? 115.109 148.207 124.436 1.00 118.28 ? 61  MET B SD   1 
ATOM   3284 C  CE   . MET B 1 61  ? 114.850 146.991 123.147 1.00 118.28 ? 61  MET B CE   1 
ATOM   3285 N  N    . ALA B 1 62  ? 113.107 145.292 128.392 1.00 105.61 ? 62  ALA B N    1 
ATOM   3286 C  CA   . ALA B 1 62  ? 113.169 143.871 128.682 1.00 105.61 ? 62  ALA B CA   1 
ATOM   3287 C  C    . ALA B 1 62  ? 114.159 143.180 127.743 1.00 105.61 ? 62  ALA B C    1 
ATOM   3288 O  O    . ALA B 1 62  ? 114.316 143.587 126.592 1.00 105.61 ? 62  ALA B O    1 
ATOM   3289 C  CB   . ALA B 1 62  ? 111.789 143.240 128.539 1.00 105.61 ? 62  ALA B CB   1 
ATOM   3290 N  N    . PRO B 1 63  ? 114.845 142.136 128.218 1.00 99.15  ? 63  PRO B N    1 
ATOM   3291 C  CA   . PRO B 1 63  ? 115.796 141.446 127.333 1.00 99.15  ? 63  PRO B CA   1 
ATOM   3292 C  C    . PRO B 1 63  ? 115.125 140.743 126.169 1.00 99.15  ? 63  PRO B C    1 
ATOM   3293 O  O    . PRO B 1 63  ? 115.635 140.790 125.039 1.00 99.15  ? 63  PRO B O    1 
ATOM   3294 C  CB   . PRO B 1 63  ? 116.484 140.453 128.277 1.00 99.15  ? 63  PRO B CB   1 
ATOM   3295 C  CG   . PRO B 1 63  ? 115.506 140.238 129.373 1.00 99.15  ? 63  PRO B CG   1 
ATOM   3296 C  CD   . PRO B 1 63  ? 114.819 141.551 129.566 1.00 99.15  ? 63  PRO B CD   1 
ATOM   3297 N  N    . ASN B 1 64  ? 113.978 140.111 126.409 1.00 99.06  ? 64  ASN B N    1 
ATOM   3298 C  CA   . ASN B 1 64  ? 113.276 139.426 125.333 1.00 99.06  ? 64  ASN B CA   1 
ATOM   3299 C  C    . ASN B 1 64  ? 112.817 140.393 124.255 1.00 99.06  ? 64  ASN B C    1 
ATOM   3300 O  O    . ASN B 1 64  ? 112.714 140.009 123.086 1.00 99.06  ? 64  ASN B O    1 
ATOM   3301 C  CB   . ASN B 1 64  ? 112.100 138.644 125.903 1.00 99.06  ? 64  ASN B CB   1 
ATOM   3302 C  CG   . ASN B 1 64  ? 112.471 137.888 127.155 1.00 99.06  ? 64  ASN B CG   1 
ATOM   3303 O  OD1  . ASN B 1 64  ? 113.340 137.019 127.131 1.00 99.06  ? 64  ASN B OD1  1 
ATOM   3304 N  ND2  . ASN B 1 64  ? 111.818 138.217 128.260 1.00 99.06  ? 64  ASN B ND2  1 
ATOM   3305 N  N    . SER B 1 65  ? 112.557 141.651 124.620 1.00 100.92 ? 65  SER B N    1 
ATOM   3306 C  CA   . SER B 1 65  ? 112.268 142.664 123.610 1.00 100.92 ? 65  SER B CA   1 
ATOM   3307 C  C    . SER B 1 65  ? 113.462 142.869 122.690 1.00 100.92 ? 65  SER B C    1 
ATOM   3308 O  O    . SER B 1 65  ? 113.298 143.016 121.475 1.00 100.92 ? 65  SER B O    1 
ATOM   3309 C  CB   . SER B 1 65  ? 111.878 143.979 124.281 1.00 100.92 ? 65  SER B CB   1 
ATOM   3310 O  OG   . SER B 1 65  ? 112.973 144.517 125.001 1.00 100.92 ? 65  SER B OG   1 
ATOM   3311 N  N    . ILE B 1 66  ? 114.671 142.861 123.252 1.00 96.88  ? 66  ILE B N    1 
ATOM   3312 C  CA   . ILE B 1 66  ? 115.876 142.970 122.441 1.00 96.88  ? 66  ILE B CA   1 
ATOM   3313 C  C    . ILE B 1 66  ? 116.001 141.776 121.502 1.00 96.88  ? 66  ILE B C    1 
ATOM   3314 O  O    . ILE B 1 66  ? 116.288 141.932 120.304 1.00 96.88  ? 66  ILE B O    1 
ATOM   3315 C  CB   . ILE B 1 66  ? 117.113 143.099 123.346 1.00 96.88  ? 66  ILE B CB   1 
ATOM   3316 C  CG1  . ILE B 1 66  ? 116.874 144.129 124.453 1.00 96.88  ? 66  ILE B CG1  1 
ATOM   3317 C  CG2  . ILE B 1 66  ? 118.335 143.450 122.527 1.00 96.88  ? 66  ILE B CG2  1 
ATOM   3318 C  CD1  . ILE B 1 66  ? 117.961 144.141 125.507 1.00 96.88  ? 66  ILE B CD1  1 
ATOM   3319 N  N    . THR B 1 67  ? 115.782 140.566 122.032 1.00 89.12  ? 67  THR B N    1 
ATOM   3320 C  CA   . THR B 1 67  ? 115.863 139.363 121.202 1.00 89.12  ? 67  THR B CA   1 
ATOM   3321 C  C    . THR B 1 67  ? 114.870 139.427 120.054 1.00 89.12  ? 67  THR B C    1 
ATOM   3322 O  O    . THR B 1 67  ? 115.212 139.150 118.897 1.00 89.12  ? 67  THR B O    1 
ATOM   3323 C  CB   . THR B 1 67  ? 115.564 138.119 122.028 1.00 89.12  ? 67  THR B CB   1 
ATOM   3324 O  OG1  . THR B 1 67  ? 114.155 138.059 122.239 1.00 89.12  ? 67  THR B OG1  1 
ATOM   3325 C  CG2  . THR B 1 67  ? 116.196 138.205 123.372 1.00 89.12  ? 67  THR B CG2  1 
ATOM   3326 N  N    . LEU B 1 68  ? 113.629 139.800 120.364 1.00 85.67  ? 68  LEU B N    1 
ATOM   3327 C  CA   . LEU B 1 68  ? 112.577 139.850 119.361 1.00 85.67  ? 68  LEU B CA   1 
ATOM   3328 C  C    . LEU B 1 68  ? 112.860 140.920 118.321 1.00 85.67  ? 68  LEU B C    1 
ATOM   3329 O  O    . LEU B 1 68  ? 112.591 140.714 117.135 1.00 85.67  ? 68  LEU B O    1 
ATOM   3330 C  CB   . LEU B 1 68  ? 111.229 140.093 120.033 1.00 85.67  ? 68  LEU B CB   1 
ATOM   3331 C  CG   . LEU B 1 68  ? 110.003 140.097 119.122 1.00 85.67  ? 68  LEU B CG   1 
ATOM   3332 C  CD1  . LEU B 1 68  ? 109.591 138.676 118.856 1.00 85.67  ? 68  LEU B CD1  1 
ATOM   3333 C  CD2  . LEU B 1 68  ? 108.857 140.869 119.755 1.00 85.67  ? 68  LEU B CD2  1 
ATOM   3334 N  N    . LEU B 1 69  ? 113.401 142.065 118.738 1.00 84.27  ? 69  LEU B N    1 
ATOM   3335 C  CA   . LEU B 1 69  ? 113.723 143.115 117.779 1.00 84.27  ? 69  LEU B CA   1 
ATOM   3336 C  C    . LEU B 1 69  ? 114.791 142.644 116.804 1.00 84.27  ? 69  LEU B C    1 
ATOM   3337 O  O    . LEU B 1 69  ? 114.666 142.840 115.587 1.00 84.27  ? 69  LEU B O    1 
ATOM   3338 C  CB   . LEU B 1 69  ? 114.182 144.373 118.507 1.00 84.27  ? 69  LEU B CB   1 
ATOM   3339 C  CG   . LEU B 1 69  ? 114.759 145.466 117.609 1.00 84.27  ? 69  LEU B CG   1 
ATOM   3340 C  CD1  . LEU B 1 69  ? 113.691 146.014 116.671 1.00 84.27  ? 69  LEU B CD1  1 
ATOM   3341 C  CD2  . LEU B 1 69  ? 115.364 146.569 118.449 1.00 84.27  ? 69  LEU B CD2  1 
ATOM   3342 N  N    . GLY B 1 70  ? 115.837 141.996 117.321 1.00 79.87  ? 70  GLY B N    1 
ATOM   3343 C  CA   . GLY B 1 70  ? 116.868 141.473 116.439 1.00 79.87  ? 70  GLY B CA   1 
ATOM   3344 C  C    . GLY B 1 70  ? 116.335 140.433 115.471 1.00 79.87  ? 70  GLY B C    1 
ATOM   3345 O  O    . GLY B 1 70  ? 116.604 140.493 114.264 1.00 79.87  ? 70  GLY B O    1 
ATOM   3346 N  N    . LEU B 1 71  ? 115.546 139.485 115.983 1.00 71.65  ? 71  LEU B N    1 
ATOM   3347 C  CA   . LEU B 1 71  ? 114.988 138.446 115.126 1.00 71.65  ? 71  LEU B CA   1 
ATOM   3348 C  C    . LEU B 1 71  ? 114.060 139.032 114.075 1.00 71.65  ? 71  LEU B C    1 
ATOM   3349 O  O    . LEU B 1 71  ? 114.075 138.602 112.919 1.00 71.65  ? 71  LEU B O    1 
ATOM   3350 C  CB   . LEU B 1 71  ? 114.243 137.409 115.960 1.00 71.65  ? 71  LEU B CB   1 
ATOM   3351 C  CG   . LEU B 1 71  ? 113.794 136.195 115.153 1.00 71.65  ? 71  LEU B CG   1 
ATOM   3352 C  CD1  . LEU B 1 71  ? 114.926 135.651 114.312 1.00 71.65  ? 71  LEU B CD1  1 
ATOM   3353 C  CD2  . LEU B 1 71  ? 113.238 135.120 116.055 1.00 71.65  ? 71  LEU B CD2  1 
ATOM   3354 N  N    . ALA B 1 72  ? 113.243 140.016 114.456 1.00 72.18  ? 72  ALA B N    1 
ATOM   3355 C  CA   . ALA B 1 72  ? 112.319 140.624 113.509 1.00 72.18  ? 72  ALA B CA   1 
ATOM   3356 C  C    . ALA B 1 72  ? 113.066 141.353 112.406 1.00 72.18  ? 72  ALA B C    1 
ATOM   3357 O  O    . ALA B 1 72  ? 112.700 141.246 111.230 1.00 72.18  ? 72  ALA B O    1 
ATOM   3358 C  CB   . ALA B 1 72  ? 111.370 141.576 114.235 1.00 72.18  ? 72  ALA B CB   1 
ATOM   3359 N  N    . VAL B 1 73  ? 114.122 142.090 112.763 1.00 69.80  ? 73  VAL B N    1 
ATOM   3360 C  CA   . VAL B 1 73  ? 114.887 142.804 111.747 1.00 69.80  ? 73  VAL B CA   1 
ATOM   3361 C  C    . VAL B 1 73  ? 115.533 141.824 110.778 1.00 69.80  ? 73  VAL B C    1 
ATOM   3362 O  O    . VAL B 1 73  ? 115.456 141.999 109.550 1.00 69.80  ? 73  VAL B O    1 
ATOM   3363 C  CB   . VAL B 1 73  ? 115.926 143.723 112.411 1.00 69.80  ? 73  VAL B CB   1 
ATOM   3364 C  CG1  . VAL B 1 73  ? 116.914 144.231 111.387 1.00 69.80  ? 73  VAL B CG1  1 
ATOM   3365 C  CG2  . VAL B 1 73  ? 115.229 144.892 113.077 1.00 69.80  ? 73  VAL B CG2  1 
ATOM   3366 N  N    . ASN B 1 74  ? 116.145 140.760 111.309 1.00 68.15  ? 74  ASN B N    1 
ATOM   3367 C  CA   . ASN B 1 74  ? 116.793 139.789 110.431 1.00 68.15  ? 74  ASN B CA   1 
ATOM   3368 C  C    . ASN B 1 74  ? 115.788 139.078 109.537 1.00 68.15  ? 74  ASN B C    1 
ATOM   3369 O  O    . ASN B 1 74  ? 116.029 138.905 108.335 1.00 68.15  ? 74  ASN B O    1 
ATOM   3370 C  CB   . ASN B 1 74  ? 117.575 138.769 111.249 1.00 68.15  ? 74  ASN B CB   1 
ATOM   3371 C  CG   . ASN B 1 74  ? 118.242 137.733 110.383 1.00 68.15  ? 74  ASN B CG   1 
ATOM   3372 O  OD1  . ASN B 1 74  ? 119.276 137.990 109.769 1.00 68.15  ? 74  ASN B OD1  1 
ATOM   3373 N  ND2  . ASN B 1 74  ? 117.645 136.554 110.312 1.00 68.15  ? 74  ASN B ND2  1 
ATOM   3374 N  N    . VAL B 1 75  ? 114.649 138.670 110.101 1.00 64.96  ? 75  VAL B N    1 
ATOM   3375 C  CA   . VAL B 1 75  ? 113.643 137.961 109.324 1.00 64.96  ? 75  VAL B CA   1 
ATOM   3376 C  C    . VAL B 1 75  ? 113.070 138.853 108.233 1.00 64.96  ? 75  VAL B C    1 
ATOM   3377 O  O    . VAL B 1 75  ? 112.906 138.417 107.092 1.00 64.96  ? 75  VAL B O    1 
ATOM   3378 C  CB   . VAL B 1 75  ? 112.544 137.413 110.252 1.00 64.96  ? 75  VAL B CB   1 
ATOM   3379 C  CG1  . VAL B 1 75  ? 111.286 137.090 109.472 1.00 64.96  ? 75  VAL B CG1  1 
ATOM   3380 C  CG2  . VAL B 1 75  ? 113.040 136.171 110.955 1.00 64.96  ? 75  VAL B CG2  1 
ATOM   3381 N  N    . VAL B 1 76  ? 112.788 140.118 108.550 1.00 66.56  ? 76  VAL B N    1 
ATOM   3382 C  CA   . VAL B 1 76  ? 112.209 141.014 107.553 1.00 66.56  ? 76  VAL B CA   1 
ATOM   3383 C  C    . VAL B 1 76  ? 113.194 141.264 106.414 1.00 66.56  ? 76  VAL B C    1 
ATOM   3384 O  O    . VAL B 1 76  ? 112.827 141.192 105.232 1.00 66.56  ? 76  VAL B O    1 
ATOM   3385 C  CB   . VAL B 1 76  ? 111.752 142.326 108.215 1.00 66.56  ? 76  VAL B CB   1 
ATOM   3386 C  CG1  . VAL B 1 76  ? 111.642 143.443 107.192 1.00 66.56  ? 76  VAL B CG1  1 
ATOM   3387 C  CG2  . VAL B 1 76  ? 110.420 142.122 108.909 1.00 66.56  ? 76  VAL B CG2  1 
ATOM   3388 N  N    . THR B 1 77  ? 114.462 141.539 106.744 1.00 65.34  ? 77  THR B N    1 
ATOM   3389 C  CA   . THR B 1 77  ? 115.431 141.805 105.683 1.00 65.34  ? 77  THR B CA   1 
ATOM   3390 C  C    . THR B 1 77  ? 115.667 140.574 104.817 1.00 65.34  ? 77  THR B C    1 
ATOM   3391 O  O    . THR B 1 77  ? 115.710 140.676 103.582 1.00 65.34  ? 77  THR B O    1 
ATOM   3392 C  CB   . THR B 1 77  ? 116.748 142.297 106.272 1.00 65.34  ? 77  THR B CB   1 
ATOM   3393 O  OG1  . THR B 1 77  ? 117.183 141.387 107.284 1.00 65.34  ? 77  THR B OG1  1 
ATOM   3394 C  CG2  . THR B 1 77  ? 116.564 143.672 106.876 1.00 65.34  ? 77  THR B CG2  1 
ATOM   3395 N  N    . THR B 1 78  ? 115.800 139.399 105.433 1.00 60.86  ? 78  THR B N    1 
ATOM   3396 C  CA   . THR B 1 78  ? 116.006 138.199 104.636 1.00 60.86  ? 78  THR B CA   1 
ATOM   3397 C  C    . THR B 1 78  ? 114.762 137.839 103.833 1.00 60.86  ? 78  THR B C    1 
ATOM   3398 O  O    . THR B 1 78  ? 114.879 137.297 102.732 1.00 60.86  ? 78  THR B O    1 
ATOM   3399 C  CB   . THR B 1 78  ? 116.427 137.038 105.525 1.00 60.86  ? 78  THR B CB   1 
ATOM   3400 O  OG1  . THR B 1 78  ? 117.408 137.500 106.459 1.00 60.86  ? 78  THR B OG1  1 
ATOM   3401 C  CG2  . THR B 1 78  ? 117.038 135.938 104.694 1.00 60.86  ? 78  THR B CG2  1 
ATOM   3402 N  N    . LEU B 1 79  ? 113.570 138.156 104.340 1.00 62.74  ? 79  LEU B N    1 
ATOM   3403 C  CA   . LEU B 1 79  ? 112.364 137.903 103.561 1.00 62.74  ? 79  LEU B CA   1 
ATOM   3404 C  C    . LEU B 1 79  ? 112.289 138.819 102.349 1.00 62.74  ? 79  LEU B C    1 
ATOM   3405 O  O    . LEU B 1 79  ? 111.857 138.394 101.275 1.00 62.74  ? 79  LEU B O    1 
ATOM   3406 C  CB   . LEU B 1 79  ? 111.123 138.067 104.429 1.00 62.74  ? 79  LEU B CB   1 
ATOM   3407 C  CG   . LEU B 1 79  ? 110.701 136.845 105.242 1.00 62.74  ? 79  LEU B CG   1 
ATOM   3408 C  CD1  . LEU B 1 79  ? 109.296 137.041 105.776 1.00 62.74  ? 79  LEU B CD1  1 
ATOM   3409 C  CD2  . LEU B 1 79  ? 110.793 135.581 104.411 1.00 62.74  ? 79  LEU B CD2  1 
ATOM   3410 N  N    . VAL B 1 80  ? 112.707 140.078 102.497 1.00 63.63  ? 80  VAL B N    1 
ATOM   3411 C  CA   . VAL B 1 80  ? 112.738 140.978 101.344 1.00 63.63  ? 80  VAL B CA   1 
ATOM   3412 C  C    . VAL B 1 80  ? 113.740 140.481 100.308 1.00 63.63  ? 80  VAL B C    1 
ATOM   3413 O  O    . VAL B 1 80  ? 113.446 140.438 99.103  1.00 63.63  ? 80  VAL B O    1 
ATOM   3414 C  CB   . VAL B 1 80  ? 113.046 142.416 101.797 1.00 63.63  ? 80  VAL B CB   1 
ATOM   3415 C  CG1  . VAL B 1 80  ? 113.515 143.257 100.632 1.00 63.63  ? 80  VAL B CG1  1 
ATOM   3416 C  CG2  . VAL B 1 80  ? 111.812 143.040 102.418 1.00 63.63  ? 80  VAL B CG2  1 
ATOM   3417 N  N    . LEU B 1 81  ? 114.924 140.070 100.765 1.00 61.62  ? 81  LEU B N    1 
ATOM   3418 C  CA   . LEU B 1 81  ? 115.913 139.532 99.837  1.00 61.62  ? 81  LEU B CA   1 
ATOM   3419 C  C    . LEU B 1 81  ? 115.425 138.255 99.163  1.00 61.62  ? 81  LEU B C    1 
ATOM   3420 O  O    . LEU B 1 81  ? 115.751 138.011 98.000  1.00 61.62  ? 81  LEU B O    1 
ATOM   3421 C  CB   . LEU B 1 81  ? 117.224 139.274 100.566 1.00 61.62  ? 81  LEU B CB   1 
ATOM   3422 C  CG   . LEU B 1 81  ? 118.459 139.029 99.712  1.00 61.62  ? 81  LEU B CG   1 
ATOM   3423 C  CD1  . LEU B 1 81  ? 119.620 139.659 100.415 1.00 61.62  ? 81  LEU B CD1  1 
ATOM   3424 C  CD2  . LEU B 1 81  ? 118.711 137.558 99.544  1.00 61.62  ? 81  LEU B CD2  1 
ATOM   3425 N  N    . ILE B 1 82  ? 114.662 137.426 99.875  1.00 61.08  ? 82  ILE B N    1 
ATOM   3426 C  CA   . ILE B 1 82  ? 114.064 136.248 99.257  1.00 61.08  ? 82  ILE B CA   1 
ATOM   3427 C  C    . ILE B 1 82  ? 113.011 136.668 98.237  1.00 61.08  ? 82  ILE B C    1 
ATOM   3428 O  O    . ILE B 1 82  ? 112.882 136.055 97.172  1.00 61.08  ? 82  ILE B O    1 
ATOM   3429 C  CB   . ILE B 1 82  ? 113.482 135.326 100.344 1.00 61.08  ? 82  ILE B CB   1 
ATOM   3430 C  CG1  . ILE B 1 82  ? 114.596 134.557 101.037 1.00 61.08  ? 82  ILE B CG1  1 
ATOM   3431 C  CG2  . ILE B 1 82  ? 112.505 134.334 99.766  1.00 61.08  ? 82  ILE B CG2  1 
ATOM   3432 C  CD1  . ILE B 1 82  ? 114.197 133.997 102.368 1.00 61.08  ? 82  ILE B CD1  1 
ATOM   3433 N  N    . SER B 1 83  ? 112.273 137.736 98.536  1.00 64.22  ? 83  SER B N    1 
ATOM   3434 C  CA   . SER B 1 83  ? 111.249 138.221 97.618  1.00 64.22  ? 83  SER B CA   1 
ATOM   3435 C  C    . SER B 1 83  ? 111.855 138.659 96.296  1.00 64.22  ? 83  SER B C    1 
ATOM   3436 O  O    . SER B 1 83  ? 111.289 138.390 95.231  1.00 64.22  ? 83  SER B O    1 
ATOM   3437 C  CB   . SER B 1 83  ? 110.479 139.376 98.255  1.00 64.22  ? 83  SER B CB   1 
ATOM   3438 O  OG   . SER B 1 83  ? 109.730 140.080 97.281  1.00 64.22  ? 83  SER B OG   1 
ATOM   3439 N  N    . TYR B 1 84  ? 113.001 139.330 96.333  1.00 70.91  ? 84  TYR B N    1 
ATOM   3440 C  CA   . TYR B 1 84  ? 113.591 139.716 95.058  1.00 70.91  ? 84  TYR B CA   1 
ATOM   3441 C  C    . TYR B 1 84  ? 114.374 138.599 94.386  1.00 70.91  ? 84  TYR B C    1 
ATOM   3442 O  O    . TYR B 1 84  ? 114.770 138.765 93.231  1.00 70.91  ? 84  TYR B O    1 
ATOM   3443 C  CB   . TYR B 1 84  ? 114.484 140.943 95.220  1.00 70.91  ? 84  TYR B CB   1 
ATOM   3444 C  CG   . TYR B 1 84  ? 113.717 142.235 95.116  1.00 70.91  ? 84  TYR B CG   1 
ATOM   3445 C  CD1  . TYR B 1 84  ? 112.329 142.242 95.139  1.00 70.91  ? 84  TYR B CD1  1 
ATOM   3446 C  CD2  . TYR B 1 84  ? 114.375 143.445 94.975  1.00 70.91  ? 84  TYR B CD2  1 
ATOM   3447 C  CE1  . TYR B 1 84  ? 111.618 143.418 95.039  1.00 70.91  ? 84  TYR B CE1  1 
ATOM   3448 C  CE2  . TYR B 1 84  ? 113.672 144.629 94.875  1.00 70.91  ? 84  TYR B CE2  1 
ATOM   3449 C  CZ   . TYR B 1 84  ? 112.292 144.608 94.909  1.00 70.91  ? 84  TYR B CZ   1 
ATOM   3450 O  OH   . TYR B 1 84  ? 111.584 145.786 94.807  1.00 70.91  ? 84  TYR B OH   1 
ATOM   3451 N  N    . CYS B 1 85  ? 114.588 137.470 95.054  1.00 71.61  ? 85  CYS B N    1 
ATOM   3452 C  CA   . CYS B 1 85  ? 115.283 136.328 94.454  1.00 71.61  ? 85  CYS B CA   1 
ATOM   3453 C  C    . CYS B 1 85  ? 114.737 135.037 95.035  1.00 71.61  ? 85  CYS B C    1 
ATOM   3454 O  O    . CYS B 1 85  ? 115.349 134.423 95.915  1.00 71.61  ? 85  CYS B O    1 
ATOM   3455 C  CB   . CYS B 1 85  ? 116.796 136.406 94.671  1.00 71.61  ? 85  CYS B CB   1 
ATOM   3456 S  SG   . CYS B 1 85  ? 117.662 137.760 93.860  1.00 71.61  ? 85  CYS B SG   1 
ATOM   3457 N  N    . PRO B 1 86  ? 113.565 134.595 94.575  1.00 65.96  ? 86  PRO B N    1 
ATOM   3458 C  CA   . PRO B 1 86  ? 113.028 133.320 95.066  1.00 65.96  ? 86  PRO B CA   1 
ATOM   3459 C  C    . PRO B 1 86  ? 113.909 132.137 94.734  1.00 65.96  ? 86  PRO B C    1 
ATOM   3460 O  O    . PRO B 1 86  ? 113.978 131.189 95.520  1.00 65.96  ? 86  PRO B O    1 
ATOM   3461 C  CB   . PRO B 1 86  ? 111.666 133.227 94.373  1.00 65.96  ? 86  PRO B CB   1 
ATOM   3462 C  CG   . PRO B 1 86  ? 111.830 134.021 93.135  1.00 65.96  ? 86  PRO B CG   1 
ATOM   3463 C  CD   . PRO B 1 86  ? 112.753 135.152 93.481  1.00 65.96  ? 86  PRO B CD   1 
ATOM   3464 N  N    . THR B 1 87  ? 114.579 132.163 93.593  1.00 74.93  ? 87  THR B N    1 
ATOM   3465 C  CA   . THR B 1 87  ? 115.574 131.169 93.255  1.00 74.93  ? 87  THR B CA   1 
ATOM   3466 C  C    . THR B 1 87  ? 116.942 131.711 93.637  1.00 74.93  ? 87  THR B C    1 
ATOM   3467 O  O    . THR B 1 87  ? 117.062 132.736 94.309  1.00 74.93  ? 87  THR B O    1 
ATOM   3468 C  CB   . THR B 1 87  ? 115.511 130.815 91.773  1.00 74.93  ? 87  THR B CB   1 
ATOM   3469 O  OG1  . THR B 1 87  ? 115.783 131.983 90.994  1.00 74.93  ? 87  THR B OG1  1 
ATOM   3470 C  CG2  . THR B 1 87  ? 114.131 130.296 91.411  1.00 74.93  ? 87  THR B CG2  1 
ATOM   3471 N  N    . ALA B 1 88  ? 117.991 131.029 93.197  1.00 80.77  ? 88  ALA B N    1 
ATOM   3472 C  CA   . ALA B 1 88  ? 119.339 131.438 93.556  1.00 80.77  ? 88  ALA B CA   1 
ATOM   3473 C  C    . ALA B 1 88  ? 120.236 131.561 92.330  1.00 80.77  ? 88  ALA B C    1 
ATOM   3474 O  O    . ALA B 1 88  ? 121.449 131.363 92.424  1.00 80.77  ? 88  ALA B O    1 
ATOM   3475 C  CB   . ALA B 1 88  ? 119.939 130.464 94.567  1.00 80.77  ? 88  ALA B CB   1 
ATOM   3476 N  N    . THR B 1 89  ? 119.662 131.892 91.174  1.00 84.92  ? 89  THR B N    1 
ATOM   3477 C  CA   . THR B 1 89  ? 120.437 132.039 89.947  1.00 84.92  ? 89  THR B CA   1 
ATOM   3478 C  C    . THR B 1 89  ? 120.369 133.448 89.373  1.00 84.92  ? 89  THR B C    1 
ATOM   3479 O  O    . THR B 1 89  ? 120.663 133.636 88.188  1.00 84.92  ? 89  THR B O    1 
ATOM   3480 C  CB   . THR B 1 89  ? 119.972 131.036 88.888  1.00 84.92  ? 89  THR B CB   1 
ATOM   3481 O  OG1  . THR B 1 89  ? 118.618 131.322 88.516  1.00 84.92  ? 89  THR B OG1  1 
ATOM   3482 C  CG2  . THR B 1 89  ? 120.063 129.619 89.416  1.00 84.92  ? 89  THR B CG2  1 
ATOM   3483 N  N    . GLU B 1 90  ? 119.983 134.434 90.172  1.00 85.55  ? 90  GLU B N    1 
ATOM   3484 C  CA   . GLU B 1 90  ? 119.795 135.797 89.699  1.00 85.55  ? 90  GLU B CA   1 
ATOM   3485 C  C    . GLU B 1 90  ? 120.177 136.778 90.793  1.00 85.55  ? 90  GLU B C    1 
ATOM   3486 O  O    . GLU B 1 90  ? 120.171 136.450 91.981  1.00 85.55  ? 90  GLU B O    1 
ATOM   3487 C  CB   . GLU B 1 90  ? 118.350 136.040 89.242  1.00 85.55  ? 90  GLU B CB   1 
ATOM   3488 C  CG   . GLU B 1 90  ? 117.324 136.052 90.360  1.00 85.55  ? 90  GLU B CG   1 
ATOM   3489 C  CD   . GLU B 1 90  ? 117.108 134.676 90.955  1.00 85.55  ? 90  GLU B CD   1 
ATOM   3490 O  OE1  . GLU B 1 90  ? 117.415 133.680 90.271  1.00 85.55  ? 90  GLU B OE1  1 
ATOM   3491 O  OE2  . GLU B 1 90  ? 116.638 134.572 92.101  1.00 85.55  ? 90  GLU B OE2  1 
ATOM   3492 N  N    . GLU B 1 91  ? 120.499 137.999 90.375  1.00 96.90  ? 91  GLU B N    1 
ATOM   3493 C  CA   . GLU B 1 91  ? 121.047 139.008 91.270  1.00 96.90  ? 91  GLU B CA   1 
ATOM   3494 C  C    . GLU B 1 91  ? 119.972 140.009 91.671  1.00 96.90  ? 91  GLU B C    1 
ATOM   3495 O  O    . GLU B 1 91  ? 119.257 140.543 90.819  1.00 96.90  ? 91  GLU B O    1 
ATOM   3496 C  CB   . GLU B 1 91  ? 122.226 139.737 90.623  1.00 96.90  ? 91  GLU B CB   1 
ATOM   3497 C  CG   . GLU B 1 91  ? 122.001 140.174 89.185  1.00 96.90  ? 91  GLU B CG   1 
ATOM   3498 C  CD   . GLU B 1 91  ? 123.007 141.216 88.739  1.00 96.90  ? 91  GLU B CD   1 
ATOM   3499 O  OE1  . GLU B 1 91  ? 123.835 141.637 89.574  1.00 96.90  ? 91  GLU B OE1  1 
ATOM   3500 O  OE2  . GLU B 1 91  ? 122.968 141.620 87.558  1.00 96.90  ? 91  GLU B OE2  1 
ATOM   3501 N  N    . ALA B 1 92  ? 119.855 140.240 92.969  1.00 94.71  ? 92  ALA B N    1 
ATOM   3502 C  CA   . ALA B 1 92  ? 119.053 141.323 93.500  1.00 94.71  ? 92  ALA B CA   1 
ATOM   3503 C  C    . ALA B 1 92  ? 119.854 142.617 93.461  1.00 94.71  ? 92  ALA B C    1 
ATOM   3504 O  O    . ALA B 1 92  ? 121.078 142.591 93.306  1.00 94.71  ? 92  ALA B O    1 
ATOM   3505 C  CB   . ALA B 1 92  ? 118.628 141.000 94.930  1.00 94.71  ? 92  ALA B CB   1 
ATOM   3506 N  N    . PRO B 1 93  ? 119.191 143.770 93.566  1.00 98.41  ? 93  PRO B N    1 
ATOM   3507 C  CA   . PRO B 1 93  ? 119.936 145.030 93.668  1.00 98.41  ? 93  PRO B CA   1 
ATOM   3508 C  C    . PRO B 1 93  ? 120.794 145.074 94.926  1.00 98.41  ? 93  PRO B C    1 
ATOM   3509 O  O    . PRO B 1 93  ? 120.496 144.427 95.930  1.00 98.41  ? 93  PRO B O    1 
ATOM   3510 C  CB   . PRO B 1 93  ? 118.830 146.091 93.699  1.00 98.41  ? 93  PRO B CB   1 
ATOM   3511 C  CG   . PRO B 1 93  ? 117.690 145.454 92.987  1.00 98.41  ? 93  PRO B CG   1 
ATOM   3512 C  CD   . PRO B 1 93  ? 117.753 144.000 93.335  1.00 98.41  ? 93  PRO B CD   1 
ATOM   3513 N  N    . TYR B 1 94  ? 121.887 145.838 94.853  1.00 97.66  ? 94  TYR B N    1 
ATOM   3514 C  CA   . TYR B 1 94  ? 122.885 145.835 95.920  1.00 97.66  ? 94  TYR B CA   1 
ATOM   3515 C  C    . TYR B 1 94  ? 122.371 146.427 97.226  1.00 97.66  ? 94  TYR B C    1 
ATOM   3516 O  O    . TYR B 1 94  ? 122.917 146.110 98.294  1.00 97.66  ? 94  TYR B O    1 
ATOM   3517 C  CB   . TYR B 1 94  ? 124.129 146.602 95.477  1.00 97.66  ? 94  TYR B CB   1 
ATOM   3518 C  CG   . TYR B 1 94  ? 123.975 148.103 95.544  1.00 97.66  ? 94  TYR B CG   1 
ATOM   3519 C  CD1  . TYR B 1 94  ? 123.149 148.778 94.652  1.00 97.66  ? 94  TYR B CD1  1 
ATOM   3520 C  CD2  . TYR B 1 94  ? 124.662 148.848 96.491  1.00 97.66  ? 94  TYR B CD2  1 
ATOM   3521 C  CE1  . TYR B 1 94  ? 123.008 150.149 94.710  1.00 97.66  ? 94  TYR B CE1  1 
ATOM   3522 C  CE2  . TYR B 1 94  ? 124.529 150.221 96.553  1.00 97.66  ? 94  TYR B CE2  1 
ATOM   3523 C  CZ   . TYR B 1 94  ? 123.698 150.864 95.660  1.00 97.66  ? 94  TYR B CZ   1 
ATOM   3524 O  OH   . TYR B 1 94  ? 123.559 152.231 95.718  1.00 97.66  ? 94  TYR B OH   1 
ATOM   3525 N  N    . TRP B 1 95  ? 121.342 147.277 97.170  1.00 91.50  ? 95  TRP B N    1 
ATOM   3526 C  CA   . TRP B 1 95  ? 120.853 147.910 98.389  1.00 91.50  ? 95  TRP B CA   1 
ATOM   3527 C  C    . TRP B 1 95  ? 120.254 146.884 99.343  1.00 91.50  ? 95  TRP B C    1 
ATOM   3528 O  O    . TRP B 1 95  ? 120.419 147.001 100.562 1.00 91.50  ? 95  TRP B O    1 
ATOM   3529 C  CB   . TRP B 1 95  ? 119.840 149.005 98.051  1.00 91.50  ? 95  TRP B CB   1 
ATOM   3530 C  CG   . TRP B 1 95  ? 118.534 148.498 97.566  1.00 91.50  ? 95  TRP B CG   1 
ATOM   3531 C  CD1  . TRP B 1 95  ? 118.188 148.248 96.277  1.00 91.50  ? 95  TRP B CD1  1 
ATOM   3532 C  CD2  . TRP B 1 95  ? 117.386 148.188 98.358  1.00 91.50  ? 95  TRP B CD2  1 
ATOM   3533 N  NE1  . TRP B 1 95  ? 116.897 147.793 96.213  1.00 91.50  ? 95  TRP B NE1  1 
ATOM   3534 C  CE2  . TRP B 1 95  ? 116.381 147.748 97.481  1.00 91.50  ? 95  TRP B CE2  1 
ATOM   3535 C  CE3  . TRP B 1 95  ? 117.110 148.238 99.725  1.00 91.50  ? 95  TRP B CE3  1 
ATOM   3536 C  CZ2  . TRP B 1 95  ? 115.123 147.358 97.926  1.00 91.50  ? 95  TRP B CZ2  1 
ATOM   3537 C  CZ3  . TRP B 1 95  ? 115.860 147.851 100.164 1.00 91.50  ? 95  TRP B CZ3  1 
ATOM   3538 C  CH2  . TRP B 1 95  ? 114.881 147.418 99.269  1.00 91.50  ? 95  TRP B CH2  1 
ATOM   3539 N  N    . THR B 1 96  ? 119.588 145.853 98.813  1.00 88.15  ? 96  THR B N    1 
ATOM   3540 C  CA   . THR B 1 96  ? 119.046 144.833 99.703  1.00 88.15  ? 96  THR B CA   1 
ATOM   3541 C  C    . THR B 1 96  ? 120.150 143.946 100.268 1.00 88.15  ? 96  THR B C    1 
ATOM   3542 O  O    . THR B 1 96  ? 120.022 143.461 101.397 1.00 88.15  ? 96  THR B O    1 
ATOM   3543 C  CB   . THR B 1 96  ? 117.969 144.003 98.997  1.00 88.15  ? 96  THR B CB   1 
ATOM   3544 O  OG1  . THR B 1 96  ? 117.240 143.246 99.970  1.00 88.15  ? 96  THR B OG1  1 
ATOM   3545 C  CG2  . THR B 1 96  ? 118.560 143.040 97.998  1.00 88.15  ? 96  THR B CG2  1 
ATOM   3546 N  N    . TYR B 1 97  ? 121.253 143.760 99.538  1.00 88.08  ? 97  TYR B N    1 
ATOM   3547 C  CA   . TYR B 1 97  ? 122.407 143.069 100.105 1.00 88.08  ? 97  TYR B CA   1 
ATOM   3548 C  C    . TYR B 1 97  ? 122.984 143.837 101.286 1.00 88.08  ? 97  TYR B C    1 
ATOM   3549 O  O    . TYR B 1 97  ? 123.249 143.259 102.350 1.00 88.08  ? 97  TYR B O    1 
ATOM   3550 C  CB   . TYR B 1 97  ? 123.476 142.848 99.038  1.00 88.08  ? 97  TYR B CB   1 
ATOM   3551 C  CG   . TYR B 1 97  ? 123.267 141.623 98.186  1.00 88.08  ? 97  TYR B CG   1 
ATOM   3552 C  CD1  . TYR B 1 97  ? 122.340 140.664 98.540  1.00 88.08  ? 97  TYR B CD1  1 
ATOM   3553 C  CD2  . TYR B 1 97  ? 124.011 141.417 97.039  1.00 88.08  ? 97  TYR B CD2  1 
ATOM   3554 C  CE1  . TYR B 1 97  ? 122.148 139.538 97.780  1.00 88.08  ? 97  TYR B CE1  1 
ATOM   3555 C  CE2  . TYR B 1 97  ? 123.825 140.296 96.266  1.00 88.08  ? 97  TYR B CE2  1 
ATOM   3556 C  CZ   . TYR B 1 97  ? 122.894 139.358 96.642  1.00 88.08  ? 97  TYR B CZ   1 
ATOM   3557 O  OH   . TYR B 1 97  ? 122.707 138.236 95.873  1.00 88.08  ? 97  TYR B OH   1 
ATOM   3558 N  N    . LEU B 1 98  ? 123.178 145.147 101.124 1.00 82.65  ? 98  LEU B N    1 
ATOM   3559 C  CA   . LEU B 1 98  ? 123.698 145.936 102.235 1.00 82.65  ? 98  LEU B CA   1 
ATOM   3560 C  C    . LEU B 1 98  ? 122.720 145.964 103.403 1.00 82.65  ? 98  LEU B C    1 
ATOM   3561 O  O    . LEU B 1 98  ? 123.135 145.886 104.566 1.00 82.65  ? 98  LEU B O    1 
ATOM   3562 C  CB   . LEU B 1 98  ? 124.030 147.353 101.773 1.00 82.65  ? 98  LEU B CB   1 
ATOM   3563 C  CG   . LEU B 1 98  ? 125.461 147.541 101.271 1.00 82.65  ? 98  LEU B CG   1 
ATOM   3564 C  CD1  . LEU B 1 98  ? 125.677 148.957 100.772 1.00 82.65  ? 98  LEU B CD1  1 
ATOM   3565 C  CD2  . LEU B 1 98  ? 126.452 147.205 102.365 1.00 82.65  ? 98  LEU B CD2  1 
ATOM   3566 N  N    . LEU B 1 99  ? 121.420 146.065 103.118 1.00 79.99  ? 99  LEU B N    1 
ATOM   3567 C  CA   . LEU B 1 99  ? 120.432 146.093 104.191 1.00 79.99  ? 99  LEU B CA   1 
ATOM   3568 C  C    . LEU B 1 99  ? 120.394 144.778 104.955 1.00 79.99  ? 99  LEU B C    1 
ATOM   3569 O  O    . LEU B 1 99  ? 120.304 144.775 106.187 1.00 79.99  ? 99  LEU B O    1 
ATOM   3570 C  CB   . LEU B 1 99  ? 119.052 146.422 103.634 1.00 79.99  ? 99  LEU B CB   1 
ATOM   3571 C  CG   . LEU B 1 99  ? 117.976 146.600 104.704 1.00 79.99  ? 99  LEU B CG   1 
ATOM   3572 C  CD1  . LEU B 1 99  ? 118.420 147.620 105.736 1.00 79.99  ? 99  LEU B CD1  1 
ATOM   3573 C  CD2  . LEU B 1 99  ? 116.656 147.022 104.082 1.00 79.99  ? 99  LEU B CD2  1 
ATOM   3574 N  N    . CYS B 1 100 ? 120.479 143.645 104.249 1.00 76.93  ? 100 CYS B N    1 
ATOM   3575 C  CA   . CYS B 1 100 ? 120.483 142.362 104.938 1.00 76.93  ? 100 CYS B CA   1 
ATOM   3576 C  C    . CYS B 1 100 ? 121.771 142.150 105.727 1.00 76.93  ? 100 CYS B C    1 
ATOM   3577 O  O    . CYS B 1 100 ? 121.744 141.549 106.808 1.00 76.93  ? 100 CYS B O    1 
ATOM   3578 C  CB   . CYS B 1 100 ? 120.269 141.231 103.939 1.00 76.93  ? 100 CYS B CB   1 
ATOM   3579 S  SG   . CYS B 1 100 ? 119.633 139.723 104.683 1.00 76.93  ? 100 CYS B SG   1 
ATOM   3580 N  N    . ALA B 1 101 ? 122.900 142.656 105.221 1.00 80.12  ? 101 ALA B N    1 
ATOM   3581 C  CA   . ALA B 1 101 ? 124.137 142.609 105.997 1.00 80.12  ? 101 ALA B CA   1 
ATOM   3582 C  C    . ALA B 1 101 ? 124.019 143.418 107.282 1.00 80.12  ? 101 ALA B C    1 
ATOM   3583 O  O    . ALA B 1 101 ? 124.442 142.967 108.355 1.00 80.12  ? 101 ALA B O    1 
ATOM   3584 C  CB   . ALA B 1 101 ? 125.301 143.125 105.160 1.00 80.12  ? 101 ALA B CB   1 
ATOM   3585 N  N    . LEU B 1 102 ? 123.450 144.621 107.189 1.00 76.65  ? 102 LEU B N    1 
ATOM   3586 C  CA   . LEU B 1 102 ? 123.265 145.439 108.380 1.00 76.65  ? 102 LEU B CA   1 
ATOM   3587 C  C    . LEU B 1 102 ? 122.297 144.773 109.343 1.00 76.65  ? 102 LEU B C    1 
ATOM   3588 O  O    . LEU B 1 102 ? 122.451 144.881 110.564 1.00 76.65  ? 102 LEU B O    1 
ATOM   3589 C  CB   . LEU B 1 102 ? 122.780 146.835 107.990 1.00 76.65  ? 102 LEU B CB   1 
ATOM   3590 C  CG   . LEU B 1 102 ? 122.769 147.936 109.054 1.00 76.65  ? 102 LEU B CG   1 
ATOM   3591 C  CD1  . LEU B 1 102 ? 123.084 149.265 108.400 1.00 76.65  ? 102 LEU B CD1  1 
ATOM   3592 C  CD2  . LEU B 1 102 ? 121.429 148.026 109.768 1.00 76.65  ? 102 LEU B CD2  1 
ATOM   3593 N  N    . GLY B 1 103 ? 121.292 144.076 108.810 1.00 74.66  ? 103 GLY B N    1 
ATOM   3594 C  CA   . GLY B 1 103 ? 120.394 143.323 109.663 1.00 74.66  ? 103 GLY B CA   1 
ATOM   3595 C  C    . GLY B 1 103 ? 121.104 142.217 110.414 1.00 74.66  ? 103 GLY B C    1 
ATOM   3596 O  O    . GLY B 1 103 ? 120.865 142.008 111.604 1.00 74.66  ? 103 GLY B O    1 
ATOM   3597 N  N    . LEU B 1 104 ? 122.000 141.502 109.734 1.00 74.24  ? 104 LEU B N    1 
ATOM   3598 C  CA   . LEU B 1 104 ? 122.760 140.454 110.409 1.00 74.24  ? 104 LEU B CA   1 
ATOM   3599 C  C    . LEU B 1 104 ? 123.650 141.032 111.505 1.00 74.24  ? 104 LEU B C    1 
ATOM   3600 O  O    . LEU B 1 104 ? 123.726 140.484 112.615 1.00 74.24  ? 104 LEU B O    1 
ATOM   3601 C  CB   . LEU B 1 104 ? 123.605 139.690 109.395 1.00 74.24  ? 104 LEU B CB   1 
ATOM   3602 C  CG   . LEU B 1 104 ? 123.871 138.235 109.752 1.00 74.24  ? 104 LEU B CG   1 
ATOM   3603 C  CD1  . LEU B 1 104 ? 122.549 137.522 109.941 1.00 74.24  ? 104 LEU B CD1  1 
ATOM   3604 C  CD2  . LEU B 1 104 ? 124.692 137.573 108.674 1.00 74.24  ? 104 LEU B CD2  1 
ATOM   3605 N  N    . PHE B 1 105 ? 124.323 142.147 111.211 1.00 78.85  ? 105 PHE B N    1 
ATOM   3606 C  CA   . PHE B 1 105 ? 125.208 142.754 112.203 1.00 78.85  ? 105 PHE B CA   1 
ATOM   3607 C  C    . PHE B 1 105 ? 124.431 143.274 113.405 1.00 78.85  ? 105 PHE B C    1 
ATOM   3608 O  O    . PHE B 1 105 ? 124.849 143.072 114.553 1.00 78.85  ? 105 PHE B O    1 
ATOM   3609 C  CB   . PHE B 1 105 ? 126.022 143.877 111.566 1.00 78.85  ? 105 PHE B CB   1 
ATOM   3610 C  CG   . PHE B 1 105 ? 127.391 144.036 112.153 1.00 78.85  ? 105 PHE B CG   1 
ATOM   3611 C  CD1  . PHE B 1 105 ? 128.382 143.111 111.884 1.00 78.85  ? 105 PHE B CD1  1 
ATOM   3612 C  CD2  . PHE B 1 105 ? 127.688 145.115 112.967 1.00 78.85  ? 105 PHE B CD2  1 
ATOM   3613 C  CE1  . PHE B 1 105 ? 129.646 143.255 112.420 1.00 78.85  ? 105 PHE B CE1  1 
ATOM   3614 C  CE2  . PHE B 1 105 ? 128.951 145.264 113.504 1.00 78.85  ? 105 PHE B CE2  1 
ATOM   3615 C  CZ   . PHE B 1 105 ? 129.930 144.333 113.230 1.00 78.85  ? 105 PHE B CZ   1 
ATOM   3616 N  N    . ILE B 1 106 ? 123.294 143.938 113.171 1.00 80.78  ? 106 ILE B N    1 
ATOM   3617 C  CA   . ILE B 1 106 ? 122.513 144.431 114.298 1.00 80.78  ? 106 ILE B CA   1 
ATOM   3618 C  C    . ILE B 1 106 ? 121.906 143.266 115.069 1.00 80.78  ? 106 ILE B C    1 
ATOM   3619 O  O    . ILE B 1 106 ? 121.731 143.353 116.287 1.00 80.78  ? 106 ILE B O    1 
ATOM   3620 C  CB   . ILE B 1 106 ? 121.445 145.447 113.840 1.00 80.78  ? 106 ILE B CB   1 
ATOM   3621 C  CG1  . ILE B 1 106 ? 120.816 146.143 115.046 1.00 80.78  ? 106 ILE B CG1  1 
ATOM   3622 C  CG2  . ILE B 1 106 ? 120.342 144.790 113.053 1.00 80.78  ? 106 ILE B CG2  1 
ATOM   3623 C  CD1  . ILE B 1 106 ? 120.003 147.365 114.690 1.00 80.78  ? 106 ILE B CD1  1 
ATOM   3624 N  N    . TYR B 1 107 ? 121.622 142.145 114.397 1.00 76.59  ? 107 TYR B N    1 
ATOM   3625 C  CA   . TYR B 1 107 ? 121.125 140.973 115.105 1.00 76.59  ? 107 TYR B CA   1 
ATOM   3626 C  C    . TYR B 1 107 ? 122.176 140.424 116.057 1.00 76.59  ? 107 TYR B C    1 
ATOM   3627 O  O    . TYR B 1 107 ? 121.876 140.099 117.213 1.00 76.59  ? 107 TYR B O    1 
ATOM   3628 C  CB   . TYR B 1 107 ? 120.703 139.894 114.112 1.00 76.59  ? 107 TYR B CB   1 
ATOM   3629 C  CG   . TYR B 1 107 ? 120.703 138.528 114.734 1.00 76.59  ? 107 TYR B CG   1 
ATOM   3630 C  CD1  . TYR B 1 107 ? 119.696 138.154 115.602 1.00 76.59  ? 107 TYR B CD1  1 
ATOM   3631 C  CD2  . TYR B 1 107 ? 121.715 137.623 114.473 1.00 76.59  ? 107 TYR B CD2  1 
ATOM   3632 C  CE1  . TYR B 1 107 ? 119.688 136.918 116.183 1.00 76.59  ? 107 TYR B CE1  1 
ATOM   3633 C  CE2  . TYR B 1 107 ? 121.722 136.387 115.056 1.00 76.59  ? 107 TYR B CE2  1 
ATOM   3634 C  CZ   . TYR B 1 107 ? 120.704 136.040 115.911 1.00 76.59  ? 107 TYR B CZ   1 
ATOM   3635 O  OH   . TYR B 1 107 ? 120.694 134.796 116.490 1.00 76.59  ? 107 TYR B OH   1 
ATOM   3636 N  N    . GLN B 1 108 ? 123.415 140.291 115.580 1.00 83.63  ? 108 GLN B N    1 
ATOM   3637 C  CA   . GLN B 1 108 ? 124.486 139.808 116.447 1.00 83.63  ? 108 GLN B CA   1 
ATOM   3638 C  C    . GLN B 1 108 ? 124.715 140.761 117.610 1.00 83.63  ? 108 GLN B C    1 
ATOM   3639 O  O    . GLN B 1 108 ? 124.899 140.329 118.759 1.00 83.63  ? 108 GLN B O    1 
ATOM   3640 C  CB   . GLN B 1 108 ? 125.773 139.622 115.648 1.00 83.63  ? 108 GLN B CB   1 
ATOM   3641 C  CG   . GLN B 1 108 ? 127.001 139.426 116.511 1.00 83.63  ? 108 GLN B CG   1 
ATOM   3642 C  CD   . GLN B 1 108 ? 128.276 139.413 115.707 1.00 83.63  ? 108 GLN B CD   1 
ATOM   3643 O  OE1  . GLN B 1 108 ? 128.426 140.169 114.751 1.00 83.63  ? 108 GLN B OE1  1 
ATOM   3644 N  NE2  . GLN B 1 108 ? 129.207 138.549 116.090 1.00 83.63  ? 108 GLN B NE2  1 
ATOM   3645 N  N    . SER B 1 109 ? 124.687 142.066 117.330 1.00 90.79  ? 109 SER B N    1 
ATOM   3646 C  CA   . SER B 1 109 ? 124.869 143.055 118.387 1.00 90.79  ? 109 SER B CA   1 
ATOM   3647 C  C    . SER B 1 109 ? 123.770 142.953 119.436 1.00 90.79  ? 109 SER B C    1 
ATOM   3648 O  O    . SER B 1 109 ? 124.048 142.980 120.641 1.00 90.79  ? 109 SER B O    1 
ATOM   3649 C  CB   . SER B 1 109 ? 124.906 144.458 117.788 1.00 90.79  ? 109 SER B CB   1 
ATOM   3650 O  OG   . SER B 1 109 ? 124.660 145.436 118.780 1.00 90.79  ? 109 SER B OG   1 
ATOM   3651 N  N    . LEU B 1 110 ? 122.518 142.801 119.002 1.00 89.18  ? 110 LEU B N    1 
ATOM   3652 C  CA   . LEU B 1 110 ? 121.427 142.716 119.963 1.00 89.18  ? 110 LEU B CA   1 
ATOM   3653 C  C    . LEU B 1 110 ? 121.456 141.405 120.735 1.00 89.18  ? 110 LEU B C    1 
ATOM   3654 O  O    . LEU B 1 110 ? 121.046 141.378 121.897 1.00 89.18  ? 110 LEU B O    1 
ATOM   3655 C  CB   . LEU B 1 110 ? 120.082 142.905 119.264 1.00 89.18  ? 110 LEU B CB   1 
ATOM   3656 C  CG   . LEU B 1 110 ? 119.842 144.314 118.719 1.00 89.18  ? 110 LEU B CG   1 
ATOM   3657 C  CD1  . LEU B 1 110 ? 118.505 144.411 118.009 1.00 89.18  ? 110 LEU B CD1  1 
ATOM   3658 C  CD2  . LEU B 1 110 ? 119.948 145.354 119.814 1.00 89.18  ? 110 LEU B CD2  1 
ATOM   3659 N  N    . ASP B 1 111 ? 121.947 140.320 120.133 1.00 87.51  ? 111 ASP B N    1 
ATOM   3660 C  CA   . ASP B 1 111 ? 122.081 139.075 120.890 1.00 87.51  ? 111 ASP B CA   1 
ATOM   3661 C  C    . ASP B 1 111 ? 123.145 139.196 121.977 1.00 87.51  ? 111 ASP B C    1 
ATOM   3662 O  O    . ASP B 1 111 ? 122.935 138.759 123.116 1.00 87.51  ? 111 ASP B O    1 
ATOM   3663 C  CB   . ASP B 1 111 ? 122.404 137.916 119.955 1.00 87.51  ? 111 ASP B CB   1 
ATOM   3664 C  CG   . ASP B 1 111 ? 122.108 136.568 120.577 1.00 87.51  ? 111 ASP B CG   1 
ATOM   3665 O  OD1  . ASP B 1 111 ? 121.657 136.531 121.739 1.00 87.51  ? 111 ASP B OD1  1 
ATOM   3666 O  OD2  . ASP B 1 111 ? 122.332 135.543 119.905 1.00 87.51  ? 111 ASP B OD2  1 
ATOM   3667 N  N    . ALA B 1 112 ? 124.297 139.780 121.654 1.00 95.94  ? 112 ALA B N    1 
ATOM   3668 C  CA   . ALA B 1 112 ? 125.298 139.979 122.700 1.00 95.94  ? 112 ALA B CA   1 
ATOM   3669 C  C    . ALA B 1 112 ? 124.764 140.900 123.790 1.00 95.94  ? 112 ALA B C    1 
ATOM   3670 O  O    . ALA B 1 112 ? 124.960 140.648 124.988 1.00 95.94  ? 112 ALA B O    1 
ATOM   3671 C  CB   . ALA B 1 112 ? 126.584 140.536 122.099 1.00 95.94  ? 112 ALA B CB   1 
ATOM   3672 N  N    . ILE B 1 113 ? 124.039 141.942 123.384 1.00 98.64  ? 113 ILE B N    1 
ATOM   3673 C  CA   . ILE B 1 113 ? 123.458 142.879 124.336 1.00 98.64  ? 113 ILE B CA   1 
ATOM   3674 C  C    . ILE B 1 113 ? 122.448 142.182 125.238 1.00 98.64  ? 113 ILE B C    1 
ATOM   3675 O  O    . ILE B 1 113 ? 122.411 142.429 126.448 1.00 98.64  ? 113 ILE B O    1 
ATOM   3676 C  CB   . ILE B 1 113 ? 122.841 144.068 123.581 1.00 98.64  ? 113 ILE B CB   1 
ATOM   3677 C  CG1  . ILE B 1 113 ? 123.930 145.081 123.232 1.00 98.64  ? 113 ILE B CG1  1 
ATOM   3678 C  CG2  . ILE B 1 113 ? 121.738 144.721 124.382 1.00 98.64  ? 113 ILE B CG2  1 
ATOM   3679 C  CD1  . ILE B 1 113 ? 123.499 146.125 122.238 1.00 98.64  ? 113 ILE B CD1  1 
ATOM   3680 N  N    . ASP B 1 114 ? 121.620 141.292 124.677 1.00 98.44  ? 114 ASP B N    1 
ATOM   3681 C  CA   . ASP B 1 114 ? 120.557 140.705 125.489 1.00 98.44  ? 114 ASP B CA   1 
ATOM   3682 C  C    . ASP B 1 114 ? 121.143 139.728 126.490 1.00 98.44  ? 114 ASP B C    1 
ATOM   3683 O  O    . ASP B 1 114 ? 120.691 139.671 127.640 1.00 98.44  ? 114 ASP B O    1 
ATOM   3684 C  CB   . ASP B 1 114 ? 119.485 140.050 124.586 1.00 98.44  ? 114 ASP B CB   1 
ATOM   3685 C  CG   . ASP B 1 114 ? 119.879 138.672 123.974 1.00 98.44  ? 114 ASP B CG   1 
ATOM   3686 O  OD1  . ASP B 1 114 ? 120.843 137.992 124.358 1.00 98.44  ? 114 ASP B OD1  1 
ATOM   3687 O  OD2  . ASP B 1 114 ? 119.236 138.291 122.983 1.00 98.44  ? 114 ASP B OD2  1 
ATOM   3688 N  N    . GLY B 1 115 ? 122.169 138.980 126.070 1.00 104.89 ? 115 GLY B N    1 
ATOM   3689 C  CA   . GLY B 1 115 ? 122.869 138.116 127.003 1.00 104.89 ? 115 GLY B CA   1 
ATOM   3690 C  C    . GLY B 1 115 ? 123.513 138.891 128.136 1.00 104.89 ? 115 GLY B C    1 
ATOM   3691 O  O    . GLY B 1 115 ? 123.409 138.510 129.305 1.00 104.89 ? 115 GLY B O    1 
ATOM   3692 N  N    . LYS B 1 116 ? 124.111 140.029 127.817 1.00 112.01 ? 116 LYS B N    1 
ATOM   3693 C  CA   . LYS B 1 116 ? 124.775 140.828 128.837 1.00 112.01 ? 116 LYS B CA   1 
ATOM   3694 C  C    . LYS B 1 116 ? 123.992 141.787 129.727 1.00 112.01 ? 116 LYS B C    1 
ATOM   3695 O  O    . LYS B 1 116 ? 124.228 141.849 130.932 1.00 112.01 ? 116 LYS B O    1 
ATOM   3696 C  CB   . LYS B 1 116 ? 125.772 141.770 128.191 1.00 112.01 ? 116 LYS B CB   1 
ATOM   3697 C  CG   . LYS B 1 116 ? 127.061 141.097 127.764 1.00 112.01 ? 116 LYS B CG   1 
ATOM   3698 C  CD   . LYS B 1 116 ? 128.173 142.116 127.575 1.00 112.01 ? 116 LYS B CD   1 
ATOM   3699 C  CE   . LYS B 1 116 ? 129.166 141.660 126.519 1.00 112.01 ? 116 LYS B CE   1 
ATOM   3700 N  NZ   . LYS B 1 116 ? 129.901 142.795 125.894 1.00 112.01 ? 116 LYS B NZ   1 
ATOM   3701 N  N    . GLN B 1 117 ? 123.122 142.571 129.118 1.00 115.47 ? 117 GLN B N    1 
ATOM   3702 C  CA   . GLN B 1 117 ? 122.334 143.506 129.874 1.00 115.47 ? 117 GLN B CA   1 
ATOM   3703 C  C    . GLN B 1 117 ? 121.163 143.012 130.597 1.00 115.47 ? 117 GLN B C    1 
ATOM   3704 O  O    . GLN B 1 117 ? 120.527 143.759 131.303 1.00 115.47 ? 117 GLN B O    1 
ATOM   3705 C  CB   . GLN B 1 117 ? 121.356 144.240 128.990 1.00 115.47 ? 117 GLN B CB   1 
ATOM   3706 C  CG   . GLN B 1 117 ? 120.588 145.345 129.684 1.00 115.47 ? 117 GLN B CG   1 
ATOM   3707 C  CD   . GLN B 1 117 ? 119.747 146.163 128.731 1.00 115.47 ? 117 GLN B CD   1 
ATOM   3708 O  OE1  . GLN B 1 117 ? 119.798 145.970 127.518 1.00 115.47 ? 117 GLN B OE1  1 
ATOM   3709 N  NE2  . GLN B 1 117 ? 118.970 147.088 129.275 1.00 115.47 ? 117 GLN B NE2  1 
ATOM   3710 N  N    . ALA B 1 118 ? 120.847 141.761 130.356 1.00 117.15 ? 118 ALA B N    1 
ATOM   3711 C  CA   . ALA B 1 118 ? 119.748 141.182 131.038 1.00 117.15 ? 118 ALA B CA   1 
ATOM   3712 C  C    . ALA B 1 118 ? 120.216 140.770 132.391 1.00 117.15 ? 118 ALA B C    1 
ATOM   3713 O  O    . ALA B 1 118 ? 119.439 140.729 133.336 1.00 117.15 ? 118 ALA B O    1 
ATOM   3714 C  CB   . ALA B 1 118 ? 119.451 139.850 130.425 1.00 117.15 ? 118 ALA B CB   1 
ATOM   3715 N  N    . ARG B 1 119 ? 121.492 140.457 132.500 1.00 120.84 ? 119 ARG B N    1 
ATOM   3716 C  CA   . ARG B 1 119 ? 121.999 139.987 133.764 1.00 120.84 ? 119 ARG B CA   1 
ATOM   3717 C  C    . ARG B 1 119 ? 121.977 141.125 134.728 1.00 120.84 ? 119 ARG B C    1 
ATOM   3718 O  O    . ARG B 1 119 ? 122.065 140.939 135.935 1.00 120.84 ? 119 ARG B O    1 
ATOM   3719 C  CB   . ARG B 1 119 ? 123.413 139.475 133.600 1.00 120.84 ? 119 ARG B CB   1 
ATOM   3720 C  CG   . ARG B 1 119 ? 123.525 138.321 132.622 1.00 120.84 ? 119 ARG B CG   1 
ATOM   3721 C  CD   . ARG B 1 119 ? 123.961 137.051 133.333 1.00 120.84 ? 119 ARG B CD   1 
ATOM   3722 N  NE   . ARG B 1 119 ? 124.070 135.924 132.415 1.00 120.84 ? 119 ARG B NE   1 
ATOM   3723 C  CZ   . ARG B 1 119 ? 125.115 135.710 131.623 1.00 120.84 ? 119 ARG B CZ   1 
ATOM   3724 N  NH1  . ARG B 1 119 ? 126.142 136.545 131.637 1.00 120.84 ? 119 ARG B NH1  1 
ATOM   3725 N  NH2  . ARG B 1 119 ? 125.135 134.661 130.817 1.00 120.84 ? 119 ARG B NH2  1 
ATOM   3726 N  N    . ARG B 1 120 ? 121.844 142.319 134.200 1.00 126.06 ? 120 ARG B N    1 
ATOM   3727 C  CA   . ARG B 1 120 ? 121.900 143.473 135.054 1.00 126.06 ? 120 ARG B CA   1 
ATOM   3728 C  C    . ARG B 1 120 ? 120.762 143.611 136.062 1.00 126.06 ? 120 ARG B C    1 
ATOM   3729 O  O    . ARG B 1 120 ? 120.892 144.365 137.017 1.00 126.06 ? 120 ARG B O    1 
ATOM   3730 C  CB   . ARG B 1 120 ? 121.823 144.728 134.180 1.00 126.06 ? 120 ARG B CB   1 
ATOM   3731 C  CG   . ARG B 1 120 ? 121.918 146.033 134.945 1.00 126.06 ? 120 ARG B CG   1 
ATOM   3732 C  CD   . ARG B 1 120 ? 121.786 147.231 134.019 1.00 126.06 ? 120 ARG B CD   1 
ATOM   3733 N  NE   . ARG B 1 120 ? 120.468 147.311 133.400 1.00 126.06 ? 120 ARG B NE   1 
ATOM   3734 C  CZ   . ARG B 1 120 ? 120.194 148.030 132.319 1.00 126.06 ? 120 ARG B CZ   1 
ATOM   3735 N  NH1  . ARG B 1 120 ? 121.154 148.725 131.728 1.00 126.06 ? 120 ARG B NH1  1 
ATOM   3736 N  NH2  . ARG B 1 120 ? 118.968 148.043 131.824 1.00 126.06 ? 120 ARG B NH2  1 
ATOM   3737 N  N    . THR B 1 121 ? 119.672 142.871 135.906 1.00 129.22 ? 121 THR B N    1 
ATOM   3738 C  CA   . THR B 1 121 ? 118.500 143.053 136.755 1.00 129.22 ? 121 THR B CA   1 
ATOM   3739 C  C    . THR B 1 121 ? 118.537 141.592 137.133 1.00 129.22 ? 121 THR B C    1 
ATOM   3740 O  O    . THR B 1 121 ? 119.243 140.815 136.496 1.00 129.22 ? 121 THR B O    1 
ATOM   3741 C  CB   . THR B 1 121 ? 117.108 143.391 136.214 1.00 129.22 ? 121 THR B CB   1 
ATOM   3742 O  OG1  . THR B 1 121 ? 116.771 142.503 135.144 1.00 129.22 ? 121 THR B OG1  1 
ATOM   3743 C  CG2  . THR B 1 121 ? 117.079 144.820 135.698 1.00 129.22 ? 121 THR B CG2  1 
ATOM   3744 N  N    . ASN B 1 122 ? 117.796 141.194 138.160 1.00 128.51 ? 122 ASN B N    1 
ATOM   3745 C  CA   . ASN B 1 122 ? 117.725 139.774 138.492 1.00 128.51 ? 122 ASN B CA   1 
ATOM   3746 C  C    . ASN B 1 122 ? 116.713 139.328 137.477 1.00 128.51 ? 122 ASN B C    1 
ATOM   3747 O  O    . ASN B 1 122 ? 115.640 138.857 137.836 1.00 128.51 ? 122 ASN B O    1 
ATOM   3748 C  CB   . ASN B 1 122 ? 116.926 139.531 139.757 1.00 128.51 ? 122 ASN B CB   1 
ATOM   3749 C  CG   . ASN B 1 122 ? 117.412 138.315 140.518 1.00 128.51 ? 122 ASN B CG   1 
ATOM   3750 O  OD1  . ASN B 1 122 ? 118.266 138.418 141.399 1.00 128.51 ? 122 ASN B OD1  1 
ATOM   3751 N  ND2  . ASN B 1 122 ? 116.881 137.148 140.169 1.00 128.51 ? 122 ASN B ND2  1 
ATOM   3752 N  N    . SER B 1 123 ? 117.043 139.505 136.213 1.00 126.79 ? 123 SER B N    1 
ATOM   3753 C  CA   . SER B 1 123 ? 116.145 139.123 135.167 1.00 126.79 ? 123 SER B CA   1 
ATOM   3754 C  C    . SER B 1 123 ? 116.642 137.809 134.709 1.00 126.79 ? 123 SER B C    1 
ATOM   3755 O  O    . SER B 1 123 ? 115.917 137.054 134.078 1.00 126.79 ? 123 SER B O    1 
ATOM   3756 C  CB   . SER B 1 123 ? 116.236 140.112 134.040 1.00 126.79 ? 123 SER B CB   1 
ATOM   3757 O  OG   . SER B 1 123 ? 117.562 140.166 133.555 1.00 126.79 ? 123 SER B OG   1 
ATOM   3758 N  N    . CYS B 1 124 ? 117.896 137.534 135.027 1.00 118.97 ? 124 CYS B N    1 
ATOM   3759 C  CA   . CYS B 1 124 ? 118.442 136.242 134.713 1.00 118.97 ? 124 CYS B CA   1 
ATOM   3760 C  C    . CYS B 1 124 ? 117.300 135.378 135.135 1.00 118.97 ? 124 CYS B C    1 
ATOM   3761 O  O    . CYS B 1 124 ? 116.878 135.411 136.286 1.00 118.97 ? 124 CYS B O    1 
ATOM   3762 C  CB   . CYS B 1 124 ? 119.721 136.042 135.493 1.00 118.97 ? 124 CYS B CB   1 
ATOM   3763 S  SG   . CYS B 1 124 ? 121.016 137.203 134.996 1.00 118.97 ? 124 CYS B SG   1 
ATOM   3764 N  N    . SER B 1 125 ? 116.770 134.612 134.210 1.00 107.21 ? 125 SER B N    1 
ATOM   3765 C  CA   . SER B 1 125 ? 115.608 133.841 134.516 1.00 107.21 ? 125 SER B CA   1 
ATOM   3766 C  C    . SER B 1 125 ? 115.714 132.828 133.430 1.00 107.21 ? 125 SER B C    1 
ATOM   3767 O  O    . SER B 1 125 ? 116.475 133.003 132.486 1.00 107.21 ? 125 SER B O    1 
ATOM   3768 C  CB   . SER B 1 125 ? 114.346 134.570 134.093 1.00 107.21 ? 125 SER B CB   1 
ATOM   3769 O  OG   . SER B 1 125 ? 114.462 135.045 132.765 1.00 107.21 ? 125 SER B OG   1 
ATOM   3770 N  N    . PRO B 1 126 ? 115.012 131.717 133.580 1.00 102.66 ? 126 PRO B N    1 
ATOM   3771 C  CA   . PRO B 1 126 ? 115.018 130.847 132.436 1.00 102.66 ? 126 PRO B CA   1 
ATOM   3772 C  C    . PRO B 1 126 ? 114.177 131.082 131.248 1.00 102.66 ? 126 PRO B C    1 
ATOM   3773 O  O    . PRO B 1 126 ? 114.047 130.181 130.455 1.00 102.66 ? 126 PRO B O    1 
ATOM   3774 C  CB   . PRO B 1 126 ? 114.480 129.660 133.172 1.00 102.66 ? 126 PRO B CB   1 
ATOM   3775 C  CG   . PRO B 1 126 ? 113.752 130.187 134.372 1.00 102.66 ? 126 PRO B CG   1 
ATOM   3776 C  CD   . PRO B 1 126 ? 113.576 131.641 134.148 1.00 102.66 ? 126 PRO B CD   1 
ATOM   3777 N  N    . LEU B 1 127 ? 113.577 132.243 131.113 1.00 98.33  ? 127 LEU B N    1 
ATOM   3778 C  CA   . LEU B 1 127 ? 112.865 132.518 129.895 1.00 98.33  ? 127 LEU B CA   1 
ATOM   3779 C  C    . LEU B 1 127 ? 113.776 133.373 129.095 1.00 98.33  ? 127 LEU B C    1 
ATOM   3780 O  O    . LEU B 1 127 ? 113.424 133.848 128.035 1.00 98.33  ? 127 LEU B O    1 
ATOM   3781 C  CB   . LEU B 1 127 ? 111.581 133.242 130.162 1.00 98.33  ? 127 LEU B CB   1 
ATOM   3782 C  CG   . LEU B 1 127 ? 110.732 133.675 128.969 1.00 98.33  ? 127 LEU B CG   1 
ATOM   3783 C  CD1  . LEU B 1 127 ? 110.261 132.456 128.195 1.00 98.33  ? 127 LEU B CD1  1 
ATOM   3784 C  CD2  . LEU B 1 127 ? 109.549 134.530 129.387 1.00 98.33  ? 127 LEU B CD2  1 
ATOM   3785 N  N    . GLY B 1 128 ? 114.942 133.616 129.655 1.00 96.66  ? 128 GLY B N    1 
ATOM   3786 C  CA   . GLY B 1 128 ? 115.928 134.428 128.985 1.00 96.66  ? 128 GLY B CA   1 
ATOM   3787 C  C    . GLY B 1 128 ? 116.645 133.515 128.070 1.00 96.66  ? 128 GLY B C    1 
ATOM   3788 O  O    . GLY B 1 128 ? 117.306 133.927 127.132 1.00 96.66  ? 128 GLY B O    1 
ATOM   3789 N  N    . GLU B 1 129 ? 116.589 132.252 128.378 1.00 94.42  ? 129 GLU B N    1 
ATOM   3790 C  CA   . GLU B 1 129 ? 117.113 131.328 127.447 1.00 94.42  ? 129 GLU B CA   1 
ATOM   3791 C  C    . GLU B 1 129 ? 115.804 130.729 127.064 1.00 94.42  ? 129 GLU B C    1 
ATOM   3792 O  O    . GLU B 1 129 ? 114.784 131.369 127.217 1.00 94.42  ? 129 GLU B O    1 
ATOM   3793 C  CB   . GLU B 1 129 ? 118.071 130.404 128.106 1.00 94.42  ? 129 GLU B CB   1 
ATOM   3794 C  CG   . GLU B 1 129 ? 119.335 131.086 128.586 1.00 94.42  ? 129 GLU B CG   1 
ATOM   3795 C  CD   . GLU B 1 129 ? 120.269 130.149 129.319 1.00 94.42  ? 129 GLU B CD   1 
ATOM   3796 O  OE1  . GLU B 1 129 ? 119.851 129.010 129.621 1.00 94.42  ? 129 GLU B OE1  1 
ATOM   3797 O  OE2  . GLU B 1 129 ? 121.421 130.544 129.589 1.00 94.42  ? 129 GLU B OE2  1 
ATOM   3798 N  N    . LEU B 1 130 ? 115.766 129.528 126.565 1.00 86.17  ? 130 LEU B N    1 
ATOM   3799 C  CA   . LEU B 1 130 ? 114.531 129.032 126.033 1.00 86.17  ? 130 LEU B CA   1 
ATOM   3800 C  C    . LEU B 1 130 ? 113.940 130.158 125.249 1.00 86.17  ? 130 LEU B C    1 
ATOM   3801 O  O    . LEU B 1 130 ? 112.738 130.240 125.138 1.00 86.17  ? 130 LEU B O    1 
ATOM   3802 C  CB   . LEU B 1 130 ? 113.589 128.606 127.091 1.00 86.17  ? 130 LEU B CB   1 
ATOM   3803 C  CG   . LEU B 1 130 ? 112.302 128.177 126.395 1.00 86.17  ? 130 LEU B CG   1 
ATOM   3804 C  CD1  . LEU B 1 130 ? 112.526 126.978 125.486 1.00 86.17  ? 130 LEU B CD1  1 
ATOM   3805 C  CD2  . LEU B 1 130 ? 111.272 127.818 127.445 1.00 86.17  ? 130 LEU B CD2  1 
ATOM   3806 N  N    . PHE B 1 131 ? 114.798 131.048 124.773 1.00 87.56  ? 131 PHE B N    1 
ATOM   3807 C  CA   . PHE B 1 131 ? 114.379 132.142 123.909 1.00 87.56  ? 131 PHE B CA   1 
ATOM   3808 C  C    . PHE B 1 131 ? 115.588 132.397 123.042 1.00 87.56  ? 131 PHE B C    1 
ATOM   3809 O  O    . PHE B 1 131 ? 115.574 132.054 121.882 1.00 87.56  ? 131 PHE B O    1 
ATOM   3810 C  CB   . PHE B 1 131 ? 114.007 133.395 124.664 1.00 87.56  ? 131 PHE B CB   1 
ATOM   3811 C  CG   . PHE B 1 131 ? 113.644 134.546 123.795 1.00 87.56  ? 131 PHE B CG   1 
ATOM   3812 C  CD1  . PHE B 1 131 ? 112.397 134.635 123.234 1.00 87.56  ? 131 PHE B CD1  1 
ATOM   3813 C  CD2  . PHE B 1 131 ? 114.564 135.534 123.537 1.00 87.56  ? 131 PHE B CD2  1 
ATOM   3814 C  CE1  . PHE B 1 131 ? 112.067 135.699 122.429 1.00 87.56  ? 131 PHE B CE1  1 
ATOM   3815 C  CE2  . PHE B 1 131 ? 114.246 136.600 122.734 1.00 87.56  ? 131 PHE B CE2  1 
ATOM   3816 C  CZ   . PHE B 1 131 ? 112.996 136.682 122.177 1.00 87.56  ? 131 PHE B CZ   1 
ATOM   3817 N  N    . ASP B 1 132 ? 116.651 132.959 123.590 1.00 82.53  ? 132 ASP B N    1 
ATOM   3818 C  CA   . ASP B 1 132 ? 117.830 133.115 122.770 1.00 82.53  ? 132 ASP B CA   1 
ATOM   3819 C  C    . ASP B 1 132 ? 118.082 131.812 122.043 1.00 82.53  ? 132 ASP B C    1 
ATOM   3820 O  O    . ASP B 1 132 ? 118.503 131.841 120.924 1.00 82.53  ? 132 ASP B O    1 
ATOM   3821 C  CB   . ASP B 1 132 ? 119.053 133.570 123.522 1.00 82.53  ? 132 ASP B CB   1 
ATOM   3822 C  CG   . ASP B 1 132 ? 120.108 134.124 122.605 1.00 82.53  ? 132 ASP B CG   1 
ATOM   3823 O  OD1  . ASP B 1 132 ? 119.760 134.554 121.495 1.00 82.53  ? 132 ASP B OD1  1 
ATOM   3824 O  OD2  . ASP B 1 132 ? 121.288 134.133 122.984 1.00 82.53  ? 132 ASP B OD2  1 
ATOM   3825 N  N    . HIS B 1 133 ? 117.843 130.662 122.629 1.00 76.42  ? 133 HIS B N    1 
ATOM   3826 C  CA   . HIS B 1 133 ? 117.949 129.471 121.864 1.00 76.42  ? 133 HIS B CA   1 
ATOM   3827 C  C    . HIS B 1 133 ? 116.796 129.126 120.985 1.00 76.42  ? 133 HIS B C    1 
ATOM   3828 O  O    . HIS B 1 133 ? 116.821 128.111 120.353 1.00 76.42  ? 133 HIS B O    1 
ATOM   3829 C  CB   . HIS B 1 133 ? 118.330 128.512 122.942 1.00 76.42  ? 133 HIS B CB   1 
ATOM   3830 C  CG   . HIS B 1 133 ? 119.673 128.776 123.527 1.00 76.42  ? 133 HIS B CG   1 
ATOM   3831 N  ND1  . HIS B 1 133 ? 119.843 129.208 124.820 1.00 76.42  ? 133 HIS B ND1  1 
ATOM   3832 C  CD2  . HIS B 1 133 ? 120.910 128.682 122.994 1.00 76.42  ? 133 HIS B CD2  1 
ATOM   3833 C  CE1  . HIS B 1 133 ? 121.130 129.359 125.065 1.00 76.42  ? 133 HIS B CE1  1 
ATOM   3834 N  NE2  . HIS B 1 133 ? 121.799 129.044 123.974 1.00 76.42  ? 133 HIS B NE2  1 
ATOM   3835 N  N    . GLY B 1 134 ? 115.710 129.869 121.029 1.00 69.91  ? 134 GLY B N    1 
ATOM   3836 C  CA   . GLY B 1 134 ? 114.732 129.744 119.957 1.00 69.91  ? 134 GLY B CA   1 
ATOM   3837 C  C    . GLY B 1 134 ? 114.936 130.773 118.858 1.00 69.91  ? 134 GLY B C    1 
ATOM   3838 O  O    . GLY B 1 134 ? 114.924 130.448 117.658 1.00 69.91  ? 134 GLY B O    1 
ATOM   3839 N  N    . CYS B 1 135 ? 115.147 132.032 119.254 1.00 76.12  ? 135 CYS B N    1 
ATOM   3840 C  CA   . CYS B 1 135 ? 115.418 133.075 118.272 1.00 76.12  ? 135 CYS B CA   1 
ATOM   3841 C  C    . CYS B 1 135 ? 116.709 132.794 117.513 1.00 76.12  ? 135 CYS B C    1 
ATOM   3842 O  O    . CYS B 1 135 ? 116.810 133.079 116.315 1.00 76.12  ? 135 CYS B O    1 
ATOM   3843 C  CB   . CYS B 1 135 ? 115.480 134.436 118.960 1.00 76.12  ? 135 CYS B CB   1 
ATOM   3844 S  SG   . CYS B 1 135 ? 113.911 134.972 119.665 1.00 76.12  ? 135 CYS B SG   1 
ATOM   3845 N  N    . ASP B 1 136 ? 117.702 132.219 118.190 1.00 71.39  ? 136 ASP B N    1 
ATOM   3846 C  CA   . ASP B 1 136 ? 118.950 131.878 117.524 1.00 71.39  ? 136 ASP B CA   1 
ATOM   3847 C  C    . ASP B 1 136 ? 118.754 130.768 116.505 1.00 71.39  ? 136 ASP B C    1 
ATOM   3848 O  O    . ASP B 1 136 ? 119.397 130.782 115.455 1.00 71.39  ? 136 ASP B O    1 
ATOM   3849 C  CB   . ASP B 1 136 ? 119.999 131.484 118.556 1.00 71.39  ? 136 ASP B CB   1 
ATOM   3850 C  CG   . ASP B 1 136 ? 120.521 132.676 119.331 1.00 71.39  ? 136 ASP B CG   1 
ATOM   3851 O  OD1  . ASP B 1 136 ? 120.399 133.805 118.822 1.00 71.39  ? 136 ASP B OD1  1 
ATOM   3852 O  OD2  . ASP B 1 136 ? 121.036 132.494 120.449 1.00 71.39  ? 136 ASP B OD2  1 
ATOM   3853 N  N    . SER B 1 137 ? 117.866 129.811 116.781 1.00 64.28  ? 137 SER B N    1 
ATOM   3854 C  CA   . SER B 1 137 ? 117.573 128.773 115.793 1.00 64.28  ? 137 SER B CA   1 
ATOM   3855 C  C    . SER B 1 137 ? 116.929 129.358 114.540 1.00 64.28  ? 137 SER B C    1 
ATOM   3856 O  O    . SER B 1 137 ? 117.342 129.060 113.400 1.00 64.28  ? 137 SER B O    1 
ATOM   3857 C  CB   . SER B 1 137 ? 116.666 127.716 116.407 1.00 64.28  ? 137 SER B CB   1 
ATOM   3858 O  OG   . SER B 1 137 ? 116.057 126.950 115.391 1.00 64.28  ? 137 SER B OG   1 
ATOM   3859 N  N    . LEU B 1 138 ? 115.909 130.200 114.733 1.00 65.42  ? 138 LEU B N    1 
ATOM   3860 C  CA   . LEU B 1 138 ? 115.279 130.850 113.582 1.00 65.42  ? 138 LEU B CA   1 
ATOM   3861 C  C    . LEU B 1 138 ? 116.287 131.674 112.794 1.00 65.42  ? 138 LEU B C    1 
ATOM   3862 O  O    . LEU B 1 138 ? 116.310 131.635 111.554 1.00 65.42  ? 138 LEU B O    1 
ATOM   3863 C  CB   . LEU B 1 138 ? 114.122 131.736 114.027 1.00 65.42  ? 138 LEU B CB   1 
ATOM   3864 C  CG   . LEU B 1 138 ? 112.755 131.078 114.037 1.00 65.42  ? 138 LEU B CG   1 
ATOM   3865 C  CD1  . LEU B 1 138 ? 111.715 132.034 114.578 1.00 65.42  ? 138 LEU B CD1  1 
ATOM   3866 C  CD2  . LEU B 1 138 ? 112.418 130.668 112.628 1.00 65.42  ? 138 LEU B CD2  1 
ATOM   3867 N  N    . SER B 1 139 ? 117.141 132.413 113.499 1.00 67.08  ? 139 SER B N    1 
ATOM   3868 C  CA   . SER B 1 139 ? 118.132 133.229 112.824 1.00 67.08  ? 139 SER B CA   1 
ATOM   3869 C  C    . SER B 1 139 ? 119.158 132.378 112.098 1.00 67.08  ? 139 SER B C    1 
ATOM   3870 O  O    . SER B 1 139 ? 119.655 132.790 111.051 1.00 67.08  ? 139 SER B O    1 
ATOM   3871 C  CB   . SER B 1 139 ? 118.820 134.146 113.823 1.00 67.08  ? 139 SER B CB   1 
ATOM   3872 O  OG   . SER B 1 139 ? 119.716 135.012 113.159 1.00 67.08  ? 139 SER B OG   1 
ATOM   3873 N  N    . THR B 1 140 ? 119.483 131.197 112.624 1.00 67.08  ? 140 THR B N    1 
ATOM   3874 C  CA   . THR B 1 140 ? 120.391 130.297 111.922 1.00 67.08  ? 140 THR B CA   1 
ATOM   3875 C  C    . THR B 1 140 ? 119.828 129.907 110.569 1.00 67.08  ? 140 THR B C    1 
ATOM   3876 O  O    . THR B 1 140 ? 120.520 129.990 109.546 1.00 67.08  ? 140 THR B O    1 
ATOM   3877 C  CB   . THR B 1 140 ? 120.645 129.046 112.754 1.00 67.08  ? 140 THR B CB   1 
ATOM   3878 O  OG1  . THR B 1 140 ? 121.240 129.410 114.004 1.00 67.08  ? 140 THR B OG1  1 
ATOM   3879 C  CG2  . THR B 1 140 ? 121.545 128.092 112.007 1.00 67.08  ? 140 THR B CG2  1 
ATOM   3880 N  N    . VAL B 1 141 ? 118.559 129.502 110.543 1.00 62.31  ? 141 VAL B N    1 
ATOM   3881 C  CA   . VAL B 1 141 ? 117.958 129.095 109.270 1.00 62.31  ? 141 VAL B CA   1 
ATOM   3882 C  C    . VAL B 1 141 ? 117.916 130.266 108.293 1.00 62.31  ? 141 VAL B C    1 
ATOM   3883 O  O    . VAL B 1 141 ? 118.328 130.146 107.127 1.00 62.31  ? 141 VAL B O    1 
ATOM   3884 C  CB   . VAL B 1 141 ? 116.558 128.513 109.502 1.00 62.31  ? 141 VAL B CB   1 
ATOM   3885 C  CG1  . VAL B 1 141 ? 115.817 128.457 108.200 1.00 62.31  ? 141 VAL B CG1  1 
ATOM   3886 C  CG2  . VAL B 1 141 ? 116.677 127.142 110.098 1.00 62.31  ? 141 VAL B CG2  1 
ATOM   3887 N  N    . PHE B 1 142 ? 117.436 131.421 108.760 1.00 63.94  ? 142 PHE B N    1 
ATOM   3888 C  CA   . PHE B 1 142 ? 117.294 132.570 107.868 1.00 63.94  ? 142 PHE B CA   1 
ATOM   3889 C  C    . PHE B 1 142 ? 118.646 133.062 107.374 1.00 63.94  ? 142 PHE B C    1 
ATOM   3890 O  O    . PHE B 1 142 ? 118.781 133.462 106.213 1.00 63.94  ? 142 PHE B O    1 
ATOM   3891 C  CB   . PHE B 1 142 ? 116.548 133.691 108.572 1.00 63.94  ? 142 PHE B CB   1 
ATOM   3892 C  CG   . PHE B 1 142 ? 115.066 133.586 108.463 1.00 63.94  ? 142 PHE B CG   1 
ATOM   3893 C  CD1  . PHE B 1 142 ? 114.398 132.500 108.989 1.00 63.94  ? 142 PHE B CD1  1 
ATOM   3894 C  CD2  . PHE B 1 142 ? 114.337 134.580 107.855 1.00 63.94  ? 142 PHE B CD2  1 
ATOM   3895 C  CE1  . PHE B 1 142 ? 113.035 132.403 108.898 1.00 63.94  ? 142 PHE B CE1  1 
ATOM   3896 C  CE2  . PHE B 1 142 ? 112.974 134.486 107.762 1.00 63.94  ? 142 PHE B CE2  1 
ATOM   3897 C  CZ   . PHE B 1 142 ? 112.324 133.398 108.286 1.00 63.94  ? 142 PHE B CZ   1 
ATOM   3898 N  N    . MET B 1 143 ? 119.662 133.026 108.231 1.00 67.02  ? 143 MET B N    1 
ATOM   3899 C  CA   . MET B 1 143 ? 120.983 133.484 107.840 1.00 67.02  ? 143 MET B CA   1 
ATOM   3900 C  C    . MET B 1 143 ? 121.614 132.536 106.837 1.00 67.02  ? 143 MET B C    1 
ATOM   3901 O  O    . MET B 1 143 ? 122.307 132.978 105.916 1.00 67.02  ? 143 MET B O    1 
ATOM   3902 C  CB   . MET B 1 143 ? 121.862 133.617 109.074 1.00 67.02  ? 143 MET B CB   1 
ATOM   3903 C  CG   . MET B 1 143 ? 123.235 134.135 108.799 1.00 67.02  ? 143 MET B CG   1 
ATOM   3904 S  SD   . MET B 1 143 ? 124.158 134.262 110.329 1.00 67.02  ? 143 MET B SD   1 
ATOM   3905 C  CE   . MET B 1 143 ? 124.423 132.530 110.653 1.00 67.02  ? 143 MET B CE   1 
ATOM   3906 N  N    . ALA B 1 144 ? 121.395 131.228 107.000 1.00 65.42  ? 144 ALA B N    1 
ATOM   3907 C  CA   . ALA B 1 144 ? 121.902 130.282 106.012 1.00 65.42  ? 144 ALA B CA   1 
ATOM   3908 C  C    . ALA B 1 144 ? 121.268 130.522 104.652 1.00 65.42  ? 144 ALA B C    1 
ATOM   3909 O  O    . ALA B 1 144 ? 121.966 130.545 103.629 1.00 65.42  ? 144 ALA B O    1 
ATOM   3910 C  CB   . ALA B 1 144 ? 121.650 128.849 106.472 1.00 65.42  ? 144 ALA B CB   1 
ATOM   3911 N  N    . VAL B 1 145 ? 119.951 130.741 104.624 1.00 60.93  ? 145 VAL B N    1 
ATOM   3912 C  CA   . VAL B 1 145 ? 119.293 131.020 103.350 1.00 60.93  ? 145 VAL B CA   1 
ATOM   3913 C  C    . VAL B 1 145 ? 119.819 132.314 102.744 1.00 60.93  ? 145 VAL B C    1 
ATOM   3914 O  O    . VAL B 1 145 ? 120.115 132.371 101.548 1.00 60.93  ? 145 VAL B O    1 
ATOM   3915 C  CB   . VAL B 1 145 ? 117.768 131.054 103.526 1.00 60.93  ? 145 VAL B CB   1 
ATOM   3916 C  CG1  . VAL B 1 145 ? 117.105 131.509 102.255 1.00 60.93  ? 145 VAL B CG1  1 
ATOM   3917 C  CG2  . VAL B 1 145 ? 117.274 129.687 103.884 1.00 60.93  ? 145 VAL B CG2  1 
ATOM   3918 N  N    . GLY B 1 146 ? 119.972 133.360 103.558 1.00 66.47  ? 146 GLY B N    1 
ATOM   3919 C  CA   . GLY B 1 146 ? 120.440 134.633 103.028 1.00 66.47  ? 146 GLY B CA   1 
ATOM   3920 C  C    . GLY B 1 146 ? 121.854 134.569 102.479 1.00 66.47  ? 146 GLY B C    1 
ATOM   3921 O  O    . GLY B 1 146 ? 122.127 135.069 101.383 1.00 66.47  ? 146 GLY B O    1 
ATOM   3922 N  N    . ALA B 1 147 ? 122.763 133.930 103.217 1.00 70.33  ? 147 ALA B N    1 
ATOM   3923 C  CA   . ALA B 1 147 ? 124.134 133.792 102.742 1.00 70.33  ? 147 ALA B CA   1 
ATOM   3924 C  C    . ALA B 1 147 ? 124.198 132.943 101.488 1.00 70.33  ? 147 ALA B C    1 
ATOM   3925 O  O    . ALA B 1 147 ? 124.977 133.236 100.575 1.00 70.33  ? 147 ALA B O    1 
ATOM   3926 C  CB   . ALA B 1 147 ? 125.008 133.193 103.833 1.00 70.33  ? 147 ALA B CB   1 
ATOM   3927 N  N    . SER B 1 148 ? 123.387 131.890 101.418 1.00 69.16  ? 148 SER B N    1 
ATOM   3928 C  CA   . SER B 1 148 ? 123.420 131.037 100.245 1.00 69.16  ? 148 SER B CA   1 
ATOM   3929 C  C    . SER B 1 148 ? 122.822 131.725 99.022  1.00 69.16  ? 148 SER B C    1 
ATOM   3930 O  O    . SER B 1 148 ? 123.252 131.458 97.898  1.00 69.16  ? 148 SER B O    1 
ATOM   3931 C  CB   . SER B 1 148 ? 122.700 129.735 100.556 1.00 69.16  ? 148 SER B CB   1 
ATOM   3932 O  OG   . SER B 1 148 ? 121.399 129.998 101.039 1.00 69.16  ? 148 SER B OG   1 
ATOM   3933 N  N    . ILE B 1 149 ? 121.836 132.602 99.214  1.00 66.16  ? 149 ILE B N    1 
ATOM   3934 C  CA   . ILE B 1 149 ? 121.331 133.364 98.078  1.00 66.16  ? 149 ILE B CA   1 
ATOM   3935 C  C    . ILE B 1 149 ? 122.368 134.363 97.599  1.00 66.16  ? 149 ILE B C    1 
ATOM   3936 O  O    . ILE B 1 149 ? 122.622 134.479 96.397  1.00 66.16  ? 149 ILE B O    1 
ATOM   3937 C  CB   . ILE B 1 149 ? 120.016 134.073 98.424  1.00 66.16  ? 149 ILE B CB   1 
ATOM   3938 C  CG1  . ILE B 1 149 ? 118.927 133.066 98.746  1.00 66.16  ? 149 ILE B CG1  1 
ATOM   3939 C  CG2  . ILE B 1 149 ? 119.572 134.922 97.265  1.00 66.16  ? 149 ILE B CG2  1 
ATOM   3940 C  CD1  . ILE B 1 149 ? 117.719 133.713 99.334  1.00 66.16  ? 149 ILE B CD1  1 
ATOM   3941 N  N    . ALA B 1 150 ? 122.979 135.101 98.527  1.00 76.41  ? 150 ALA B N    1 
ATOM   3942 C  CA   . ALA B 1 150 ? 123.870 136.185 98.126  1.00 76.41  ? 150 ALA B CA   1 
ATOM   3943 C  C    . ALA B 1 150 ? 125.081 135.676 97.363  1.00 76.41  ? 150 ALA B C    1 
ATOM   3944 O  O    . ALA B 1 150 ? 125.638 136.399 96.533  1.00 76.41  ? 150 ALA B O    1 
ATOM   3945 C  CB   . ALA B 1 150 ? 124.315 136.981 99.346  1.00 76.41  ? 150 ALA B CB   1 
ATOM   3946 N  N    . ALA B 1 151 ? 125.500 134.444 97.616  1.00 81.24  ? 151 ALA B N    1 
ATOM   3947 C  CA   . ALA B 1 151 ? 126.582 133.850 96.850  1.00 81.24  ? 151 ALA B CA   1 
ATOM   3948 C  C    . ALA B 1 151 ? 126.103 133.197 95.564  1.00 81.24  ? 151 ALA B C    1 
ATOM   3949 O  O    . ALA B 1 151 ? 126.934 132.656 94.825  1.00 81.24  ? 151 ALA B O    1 
ATOM   3950 C  CB   . ALA B 1 151 ? 127.334 132.825 97.700  1.00 81.24  ? 151 ALA B CB   1 
ATOM   3951 N  N    . ARG B 1 152 ? 124.795 133.228 95.291  1.00 87.25  ? 152 ARG B N    1 
ATOM   3952 C  CA   . ARG B 1 152 ? 124.193 132.682 94.073  1.00 87.25  ? 152 ARG B CA   1 
ATOM   3953 C  C    . ARG B 1 152 ? 124.523 131.201 93.900  1.00 87.25  ? 152 ARG B C    1 
ATOM   3954 O  O    . ARG B 1 152 ? 125.074 130.778 92.886  1.00 87.25  ? 152 ARG B O    1 
ATOM   3955 C  CB   . ARG B 1 152 ? 124.617 133.478 92.836  1.00 87.25  ? 152 ARG B CB   1 
ATOM   3956 C  CG   . ARG B 1 152 ? 123.833 134.744 92.612  1.00 87.25  ? 152 ARG B CG   1 
ATOM   3957 C  CD   . ARG B 1 152 ? 124.592 135.682 91.702  1.00 87.25  ? 152 ARG B CD   1 
ATOM   3958 N  NE   . ARG B 1 152 ? 125.096 135.003 90.514  1.00 87.25  ? 152 ARG B NE   1 
ATOM   3959 C  CZ   . ARG B 1 152 ? 124.418 134.888 89.381  1.00 87.25  ? 152 ARG B CZ   1 
ATOM   3960 N  NH1  . ARG B 1 152 ? 123.204 135.410 89.280  1.00 87.25  ? 152 ARG B NH1  1 
ATOM   3961 N  NH2  . ARG B 1 152 ? 124.950 134.253 88.346  1.00 87.25  ? 152 ARG B NH2  1 
ATOM   3962 N  N    . LEU B 1 153 ? 124.162 130.411 94.900  1.00 77.71  ? 153 LEU B N    1 
ATOM   3963 C  CA   . LEU B 1 153 ? 124.477 128.993 94.843  1.00 77.71  ? 153 LEU B CA   1 
ATOM   3964 C  C    . LEU B 1 153 ? 123.524 128.192 93.967  1.00 77.71  ? 153 LEU B C    1 
ATOM   3965 O  O    . LEU B 1 153 ? 123.676 126.970 93.881  1.00 77.71  ? 153 LEU B O    1 
ATOM   3966 C  CB   . LEU B 1 153 ? 124.501 128.396 96.243  1.00 77.71  ? 153 LEU B CB   1 
ATOM   3967 C  CG   . LEU B 1 153 ? 125.804 128.601 97.004  1.00 77.71  ? 153 LEU B CG   1 
ATOM   3968 C  CD1  . LEU B 1 153 ? 125.725 127.911 98.344  1.00 77.71  ? 153 LEU B CD1  1 
ATOM   3969 C  CD2  . LEU B 1 153 ? 126.967 128.067 96.206  1.00 77.71  ? 153 LEU B CD2  1 
ATOM   3970 N  N    . GLY B 1 154 ? 122.567 128.838 93.298  1.00 82.67  ? 154 GLY B N    1 
ATOM   3971 C  CA   . GLY B 1 154 ? 121.658 128.116 92.426  1.00 82.67  ? 154 GLY B CA   1 
ATOM   3972 C  C    . GLY B 1 154 ? 122.329 127.443 91.248  1.00 82.67  ? 154 GLY B C    1 
ATOM   3973 O  O    . GLY B 1 154 ? 121.800 126.461 90.724  1.00 82.67  ? 154 GLY B O    1 
ATOM   3974 N  N    . THR B 1 155 ? 123.487 127.946 90.821  1.00 83.17  ? 155 THR B N    1 
ATOM   3975 C  CA   . THR B 1 155 ? 124.236 127.276 89.766  1.00 83.17  ? 155 THR B CA   1 
ATOM   3976 C  C    . THR B 1 155 ? 124.848 125.968 90.241  1.00 83.17  ? 155 THR B C    1 
ATOM   3977 O  O    . THR B 1 155 ? 125.223 125.138 89.410  1.00 83.17  ? 155 THR B O    1 
ATOM   3978 C  CB   . THR B 1 155 ? 125.331 128.189 89.226  1.00 83.17  ? 155 THR B CB   1 
ATOM   3979 O  OG1  . THR B 1 155 ? 126.467 128.128 90.095  1.00 83.17  ? 155 THR B OG1  1 
ATOM   3980 C  CG2  . THR B 1 155 ? 124.831 129.618 89.144  1.00 83.17  ? 155 THR B CG2  1 
ATOM   3981 N  N    . TYR B 1 156 ? 124.964 125.772 91.550  1.00 83.06  ? 156 TYR B N    1 
ATOM   3982 C  CA   . TYR B 1 156 ? 125.409 124.511 92.137  1.00 83.06  ? 156 TYR B CA   1 
ATOM   3983 C  C    . TYR B 1 156 ? 124.385 124.100 93.181  1.00 83.06  ? 156 TYR B C    1 
ATOM   3984 O  O    . TYR B 1 156 ? 124.646 124.193 94.385  1.00 83.06  ? 156 TYR B O    1 
ATOM   3985 C  CB   . TYR B 1 156 ? 126.794 124.648 92.772  1.00 83.06  ? 156 TYR B CB   1 
ATOM   3986 C  CG   . TYR B 1 156 ? 127.961 124.461 91.835  1.00 83.06  ? 156 TYR B CG   1 
ATOM   3987 C  CD1  . TYR B 1 156 ? 127.931 123.509 90.831  1.00 83.06  ? 156 TYR B CD1  1 
ATOM   3988 C  CD2  . TYR B 1 156 ? 129.106 125.230 91.971  1.00 83.06  ? 156 TYR B CD2  1 
ATOM   3989 C  CE1  . TYR B 1 156 ? 129.005 123.333 89.978  1.00 83.06  ? 156 TYR B CE1  1 
ATOM   3990 C  CE2  . TYR B 1 156 ? 130.184 125.062 91.125  1.00 83.06  ? 156 TYR B CE2  1 
ATOM   3991 C  CZ   . TYR B 1 156 ? 130.130 124.113 90.133  1.00 83.06  ? 156 TYR B CZ   1 
ATOM   3992 O  OH   . TYR B 1 156 ? 131.202 123.942 89.288  1.00 83.06  ? 156 TYR B OH   1 
ATOM   3993 N  N    . PRO B 1 157 ? 123.205 123.643 92.752  1.00 73.01  ? 157 PRO B N    1 
ATOM   3994 C  CA   . PRO B 1 157 ? 122.091 123.468 93.699  1.00 73.01  ? 157 PRO B CA   1 
ATOM   3995 C  C    . PRO B 1 157 ? 122.382 122.512 94.832  1.00 73.01  ? 157 PRO B C    1 
ATOM   3996 O  O    . PRO B 1 157 ? 121.934 122.761 95.958  1.00 73.01  ? 157 PRO B O    1 
ATOM   3997 C  CB   . PRO B 1 157 ? 120.951 122.951 92.812  1.00 73.01  ? 157 PRO B CB   1 
ATOM   3998 C  CG   . PRO B 1 157 ? 121.345 123.320 91.434  1.00 73.01  ? 157 PRO B CG   1 
ATOM   3999 C  CD   . PRO B 1 157 ? 122.830 123.239 91.392  1.00 73.01  ? 157 PRO B CD   1 
ATOM   4000 N  N    . ASP B 1 158 ? 123.160 121.456 94.573  1.00 71.60  ? 158 ASP B N    1 
ATOM   4001 C  CA   . ASP B 1 158 ? 123.507 120.495 95.617  1.00 71.60  ? 158 ASP B CA   1 
ATOM   4002 C  C    . ASP B 1 158 ? 124.134 121.191 96.820  1.00 71.60  ? 158 ASP B C    1 
ATOM   4003 O  O    . ASP B 1 158 ? 123.664 121.028 97.955  1.00 71.60  ? 158 ASP B O    1 
ATOM   4004 C  CB   . ASP B 1 158 ? 124.452 119.439 95.051  1.00 71.60  ? 158 ASP B CB   1 
ATOM   4005 C  CG   . ASP B 1 158 ? 124.483 118.176 95.882  1.00 71.60  ? 158 ASP B CG   1 
ATOM   4006 O  OD1  . ASP B 1 158 ? 123.410 117.577 96.091  1.00 71.60  ? 158 ASP B OD1  1 
ATOM   4007 O  OD2  . ASP B 1 158 ? 125.582 117.780 96.324  1.00 71.60  ? 158 ASP B OD2  1 
ATOM   4008 N  N    . TRP B 1 159 ? 125.154 122.025 96.578  1.00 70.90  ? 159 TRP B N    1 
ATOM   4009 C  CA   . TRP B 1 159 ? 125.750 122.809 97.655  1.00 70.90  ? 159 TRP B CA   1 
ATOM   4010 C  C    . TRP B 1 159 ? 124.704 123.663 98.353  1.00 70.90  ? 159 TRP B C    1 
ATOM   4011 O  O    . TRP B 1 159 ? 124.597 123.640 99.585  1.00 70.90  ? 159 TRP B O    1 
ATOM   4012 C  CB   . TRP B 1 159 ? 126.872 123.695 97.119  1.00 70.90  ? 159 TRP B CB   1 
ATOM   4013 C  CG   . TRP B 1 159 ? 128.085 122.971 96.636  1.00 70.90  ? 159 TRP B CG   1 
ATOM   4014 C  CD1  . TRP B 1 159 ? 128.609 123.015 95.383  1.00 70.90  ? 159 TRP B CD1  1 
ATOM   4015 C  CD2  . TRP B 1 159 ? 128.935 122.107 97.397  1.00 70.90  ? 159 TRP B CD2  1 
ATOM   4016 N  NE1  . TRP B 1 159 ? 129.733 122.232 95.311  1.00 70.90  ? 159 TRP B NE1  1 
ATOM   4017 C  CE2  . TRP B 1 159 ? 129.954 121.661 96.537  1.00 70.90  ? 159 TRP B CE2  1 
ATOM   4018 C  CE3  . TRP B 1 159 ? 128.937 121.665 98.722  1.00 70.90  ? 159 TRP B CE3  1 
ATOM   4019 C  CZ2  . TRP B 1 159 ? 130.957 120.796 96.953  1.00 70.90  ? 159 TRP B CZ2  1 
ATOM   4020 C  CZ3  . TRP B 1 159 ? 129.933 120.806 99.135  1.00 70.90  ? 159 TRP B CZ3  1 
ATOM   4021 C  CH2  . TRP B 1 159 ? 130.928 120.379 98.254  1.00 70.90  ? 159 TRP B CH2  1 
ATOM   4022 N  N    . PHE B 1 160 ? 123.869 124.361 97.573  1.00 63.46  ? 160 PHE B N    1 
ATOM   4023 C  CA   . PHE B 1 160 ? 122.841 125.222 98.147  1.00 63.46  ? 160 PHE B CA   1 
ATOM   4024 C  C    . PHE B 1 160 ? 121.909 124.441 99.050  1.00 63.46  ? 160 PHE B C    1 
ATOM   4025 O  O    . PHE B 1 160 ? 121.329 125.005 99.985  1.00 63.46  ? 160 PHE B O    1 
ATOM   4026 C  CB   . PHE B 1 160 ? 122.039 125.901 97.041  1.00 63.46  ? 160 PHE B CB   1 
ATOM   4027 C  CG   . PHE B 1 160 ? 120.886 126.710 97.540  1.00 63.46  ? 160 PHE B CG   1 
ATOM   4028 C  CD1  . PHE B 1 160 ? 121.084 127.962 98.058  1.00 63.46  ? 160 PHE B CD1  1 
ATOM   4029 C  CD2  . PHE B 1 160 ? 119.601 126.217 97.478  1.00 63.46  ? 160 PHE B CD2  1 
ATOM   4030 C  CE1  . PHE B 1 160 ? 120.026 128.706 98.509  1.00 63.46  ? 160 PHE B CE1  1 
ATOM   4031 C  CE2  . PHE B 1 160 ? 118.545 126.960 97.930  1.00 63.46  ? 160 PHE B CE2  1 
ATOM   4032 C  CZ   . PHE B 1 160 ? 118.761 128.205 98.447  1.00 63.46  ? 160 PHE B CZ   1 
ATOM   4033 N  N    . PHE B 1 161 ? 121.752 123.149 98.789  1.00 58.62  ? 161 PHE B N    1 
ATOM   4034 C  CA   . PHE B 1 161 ? 121.087 122.296 99.756  1.00 58.62  ? 161 PHE B CA   1 
ATOM   4035 C  C    . PHE B 1 161 ? 122.047 121.924 100.873 1.00 58.62  ? 161 PHE B C    1 
ATOM   4036 O  O    . PHE B 1 161 ? 121.864 122.336 102.025 1.00 58.62  ? 161 PHE B O    1 
ATOM   4037 C  CB   . PHE B 1 161 ? 120.557 121.049 99.055  1.00 58.62  ? 161 PHE B CB   1 
ATOM   4038 C  CG   . PHE B 1 161 ? 120.082 119.989 99.984  1.00 58.62  ? 161 PHE B CG   1 
ATOM   4039 C  CD1  . PHE B 1 161 ? 118.826 120.058 100.546 1.00 58.62  ? 161 PHE B CD1  1 
ATOM   4040 C  CD2  . PHE B 1 161 ? 120.881 118.908 100.274 1.00 58.62  ? 161 PHE B CD2  1 
ATOM   4041 C  CE1  . PHE B 1 161 ? 118.385 119.074 101.390 1.00 58.62  ? 161 PHE B CE1  1 
ATOM   4042 C  CE2  . PHE B 1 161 ? 120.449 117.933 101.117 1.00 58.62  ? 161 PHE B CE2  1 
ATOM   4043 C  CZ   . PHE B 1 161 ? 119.197 118.009 101.677 1.00 58.62  ? 161 PHE B CZ   1 
ATOM   4044 N  N    . PHE B 1 162 ? 123.125 121.224 100.516 1.00 61.48  ? 162 PHE B N    1 
ATOM   4045 C  CA   . PHE B 1 162 ? 123.921 120.498 101.500 1.00 61.48  ? 162 PHE B CA   1 
ATOM   4046 C  C    . PHE B 1 162 ? 124.526 121.443 102.522 1.00 61.48  ? 162 PHE B C    1 
ATOM   4047 O  O    . PHE B 1 162 ? 124.312 121.285 103.731 1.00 61.48  ? 162 PHE B O    1 
ATOM   4048 C  CB   . PHE B 1 162 ? 125.004 119.699 100.781 1.00 61.48  ? 162 PHE B CB   1 
ATOM   4049 C  CG   . PHE B 1 162 ? 126.180 119.341 101.634 1.00 61.48  ? 162 PHE B CG   1 
ATOM   4050 C  CD1  . PHE B 1 162 ? 126.113 118.283 102.518 1.00 61.48  ? 162 PHE B CD1  1 
ATOM   4051 C  CD2  . PHE B 1 162 ? 127.370 120.041 101.526 1.00 61.48  ? 162 PHE B CD2  1 
ATOM   4052 C  CE1  . PHE B 1 162 ? 127.203 117.941 103.292 1.00 61.48  ? 162 PHE B CE1  1 
ATOM   4053 C  CE2  . PHE B 1 162 ? 128.461 119.705 102.299 1.00 61.48  ? 162 PHE B CE2  1 
ATOM   4054 C  CZ   . PHE B 1 162 ? 128.377 118.654 103.182 1.00 61.48  ? 162 PHE B CZ   1 
ATOM   4055 N  N    . CYS B 1 163 ? 125.219 122.480 102.040 1.00 60.70  ? 163 CYS B N    1 
ATOM   4056 C  CA   . CYS B 1 163 ? 125.785 123.498 102.917 1.00 60.70  ? 163 CYS B CA   1 
ATOM   4057 C  C    . CYS B 1 163 ? 124.739 124.060 103.863 1.00 60.70  ? 163 CYS B C    1 
ATOM   4058 O  O    . CYS B 1 163 ? 124.958 124.101 105.079 1.00 60.70  ? 163 CYS B O    1 
ATOM   4059 C  CB   . CYS B 1 163 ? 126.396 124.617 102.085 1.00 60.70  ? 163 CYS B CB   1 
ATOM   4060 S  SG   . CYS B 1 163 ? 126.789 126.087 103.026 1.00 60.70  ? 163 CYS B SG   1 
ATOM   4061 N  N    . SER B 1 164 ? 123.563 124.402 103.333 1.00 54.33  ? 164 SER B N    1 
ATOM   4062 C  CA   . SER B 1 164 ? 122.525 124.982 104.173 1.00 54.33  ? 164 SER B CA   1 
ATOM   4063 C  C    . SER B 1 164 ? 122.115 124.027 105.279 1.00 54.33  ? 164 SER B C    1 
ATOM   4064 O  O    . SER B 1 164 ? 121.987 124.431 106.437 1.00 54.33  ? 164 SER B O    1 
ATOM   4065 C  CB   . SER B 1 164 ? 121.311 125.367 103.337 1.00 54.33  ? 164 SER B CB   1 
ATOM   4066 O  OG   . SER B 1 164 ? 120.341 125.999 104.148 1.00 54.33  ? 164 SER B OG   1 
ATOM   4067 N  N    . PHE B 1 165 ? 121.971 122.742 104.959 1.00 51.20  ? 165 PHE B N    1 
ATOM   4068 C  CA   . PHE B 1 165 ? 121.565 121.820 106.010 1.00 51.20  ? 165 PHE B CA   1 
ATOM   4069 C  C    . PHE B 1 165 ? 122.710 121.538 106.967 1.00 51.20  ? 165 PHE B C    1 
ATOM   4070 O  O    . PHE B 1 165 ? 122.465 121.273 108.149 1.00 51.20  ? 165 PHE B O    1 
ATOM   4071 C  CB   . PHE B 1 165 ? 121.003 120.541 105.416 1.00 51.20  ? 165 PHE B CB   1 
ATOM   4072 C  CG   . PHE B 1 165 ? 119.531 120.604 105.194 1.00 51.20  ? 165 PHE B CG   1 
ATOM   4073 C  CD1  . PHE B 1 165 ? 119.017 121.215 104.073 1.00 51.20  ? 165 PHE B CD1  1 
ATOM   4074 C  CD2  . PHE B 1 165 ? 118.660 120.097 106.126 1.00 51.20  ? 165 PHE B CD2  1 
ATOM   4075 C  CE1  . PHE B 1 165 ? 117.663 121.293 103.876 1.00 51.20  ? 165 PHE B CE1  1 
ATOM   4076 C  CE2  . PHE B 1 165 ? 117.307 120.174 105.933 1.00 51.20  ? 165 PHE B CE2  1 
ATOM   4077 C  CZ   . PHE B 1 165 ? 116.812 120.771 104.805 1.00 51.20  ? 165 PHE B CZ   1 
ATOM   4078 N  N    . ILE B 1 166 ? 123.955 121.646 106.503 1.00 54.63  ? 166 ILE B N    1 
ATOM   4079 C  CA   . ILE B 1 166 ? 125.065 121.613 107.446 1.00 54.63  ? 166 ILE B CA   1 
ATOM   4080 C  C    . ILE B 1 166 ? 124.953 122.789 108.398 1.00 54.63  ? 166 ILE B C    1 
ATOM   4081 O  O    . ILE B 1 166 ? 125.165 122.647 109.610 1.00 54.63  ? 166 ILE B O    1 
ATOM   4082 C  CB   . ILE B 1 166 ? 126.410 121.593 106.704 1.00 54.63  ? 166 ILE B CB   1 
ATOM   4083 C  CG1  . ILE B 1 166 ? 126.544 120.288 105.933 1.00 54.63  ? 166 ILE B CG1  1 
ATOM   4084 C  CG2  . ILE B 1 166 ? 127.552 121.737 107.670 1.00 54.63  ? 166 ILE B CG2  1 
ATOM   4085 C  CD1  . ILE B 1 166 ? 126.491 119.071 106.818 1.00 54.63  ? 166 ILE B CD1  1 
ATOM   4086 N  N    . GLY B 1 167 ? 124.520 123.940 107.884 1.00 58.62  ? 167 GLY B N    1 
ATOM   4087 C  CA   . GLY B 1 167 ? 124.275 125.091 108.729 1.00 58.62  ? 167 GLY B CA   1 
ATOM   4088 C  C    . GLY B 1 167 ? 123.232 124.848 109.795 1.00 58.62  ? 167 GLY B C    1 
ATOM   4089 O  O    . GLY B 1 167 ? 123.210 125.562 110.799 1.00 58.62  ? 167 GLY B O    1 
ATOM   4090 N  N    . MET B 1 168 ? 122.368 123.853 109.606 1.00 52.40  ? 168 MET B N    1 
ATOM   4091 C  CA   . MET B 1 168 ? 121.508 123.446 110.705 1.00 52.40  ? 168 MET B CA   1 
ATOM   4092 C  C    . MET B 1 168 ? 122.238 122.479 111.621 1.00 52.40  ? 168 MET B C    1 
ATOM   4093 O  O    . MET B 1 168 ? 122.268 122.672 112.841 1.00 52.40  ? 168 MET B O    1 
ATOM   4094 C  CB   . MET B 1 168 ? 120.233 122.800 110.174 1.00 52.40  ? 168 MET B CB   1 
ATOM   4095 C  CG   . MET B 1 168 ? 119.308 123.741 109.435 1.00 52.40  ? 168 MET B CG   1 
ATOM   4096 S  SD   . MET B 1 168 ? 117.837 122.890 108.837 1.00 52.40  ? 168 MET B SD   1 
ATOM   4097 C  CE   . MET B 1 168 ? 117.023 124.209 107.950 1.00 52.40  ? 168 MET B CE   1 
ATOM   4098 N  N    . PHE B 1 169 ? 122.874 121.463 111.030 1.00 50.46  ? 169 PHE B N    1 
ATOM   4099 C  CA   . PHE B 1 169 ? 123.331 120.309 111.797 1.00 50.46  ? 169 PHE B CA   1 
ATOM   4100 C  C    . PHE B 1 169 ? 124.360 120.700 112.843 1.00 50.46  ? 169 PHE B C    1 
ATOM   4101 O  O    . PHE B 1 169 ? 124.273 120.265 113.997 1.00 50.46  ? 169 PHE B O    1 
ATOM   4102 C  CB   . PHE B 1 169 ? 123.908 119.265 110.853 1.00 50.46  ? 169 PHE B CB   1 
ATOM   4103 C  CG   . PHE B 1 169 ? 124.439 118.057 111.540 1.00 50.46  ? 169 PHE B CG   1 
ATOM   4104 C  CD1  . PHE B 1 169 ? 123.586 117.167 112.159 1.00 50.46  ? 169 PHE B CD1  1 
ATOM   4105 C  CD2  . PHE B 1 169 ? 125.796 117.805 111.564 1.00 50.46  ? 169 PHE B CD2  1 
ATOM   4106 C  CE1  . PHE B 1 169 ? 124.077 116.048 112.786 1.00 50.46  ? 169 PHE B CE1  1 
ATOM   4107 C  CE2  . PHE B 1 169 ? 126.290 116.688 112.188 1.00 50.46  ? 169 PHE B CE2  1 
ATOM   4108 C  CZ   . PHE B 1 169 ? 125.429 115.808 112.801 1.00 50.46  ? 169 PHE B CZ   1 
ATOM   4109 N  N    . VAL B 1 170 ? 125.310 121.560 112.467 1.00 55.85  ? 170 VAL B N    1 
ATOM   4110 C  CA   . VAL B 1 170 ? 126.308 122.048 113.413 1.00 55.85  ? 170 VAL B CA   1 
ATOM   4111 C  C    . VAL B 1 170 ? 125.632 122.679 114.613 1.00 55.85  ? 170 VAL B C    1 
ATOM   4112 O  O    . VAL B 1 170 ? 125.959 122.360 115.762 1.00 55.85  ? 170 VAL B O    1 
ATOM   4113 C  CB   . VAL B 1 170 ? 127.247 123.049 112.729 1.00 55.85  ? 170 VAL B CB   1 
ATOM   4114 C  CG1  . VAL B 1 170 ? 128.337 123.456 113.676 1.00 55.85  ? 170 VAL B CG1  1 
ATOM   4115 C  CG2  . VAL B 1 170 ? 127.821 122.438 111.505 1.00 55.85  ? 170 VAL B CG2  1 
ATOM   4116 N  N    . PHE B 1 171 ? 124.645 123.544 114.355 1.00 57.58  ? 171 PHE B N    1 
ATOM   4117 C  CA   . PHE B 1 171 ? 123.871 124.155 115.429 1.00 57.58  ? 171 PHE B CA   1 
ATOM   4118 C  C    . PHE B 1 171 ? 123.324 123.092 116.362 1.00 57.58  ? 171 PHE B C    1 
ATOM   4119 O  O    . PHE B 1 171 ? 123.537 123.149 117.579 1.00 57.58  ? 171 PHE B O    1 
ATOM   4120 C  CB   . PHE B 1 171 ? 122.741 124.993 114.835 1.00 57.58  ? 171 PHE B CB   1 
ATOM   4121 C  CG   . PHE B 1 171 ? 121.868 125.658 115.853 1.00 57.58  ? 171 PHE B CG   1 
ATOM   4122 C  CD1  . PHE B 1 171 ? 122.177 126.910 116.325 1.00 57.58  ? 171 PHE B CD1  1 
ATOM   4123 C  CD2  . PHE B 1 171 ? 120.719 125.043 116.315 1.00 57.58  ? 171 PHE B CD2  1 
ATOM   4124 C  CE1  . PHE B 1 171 ? 121.377 127.528 117.249 1.00 57.58  ? 171 PHE B CE1  1 
ATOM   4125 C  CE2  . PHE B 1 171 ? 119.917 125.658 117.239 1.00 57.58  ? 171 PHE B CE2  1 
ATOM   4126 C  CZ   . PHE B 1 171 ? 120.247 126.902 117.704 1.00 57.58  ? 171 PHE B CZ   1 
ATOM   4127 N  N    . TYR B 1 172 ? 122.703 122.057 115.790 1.00 52.88  ? 172 TYR B N    1 
ATOM   4128 C  CA   . TYR B 1 172 ? 122.150 120.991 116.610 1.00 52.88  ? 172 TYR B CA   1 
ATOM   4129 C  C    . TYR B 1 172 ? 123.234 120.327 117.434 1.00 52.88  ? 172 TYR B C    1 
ATOM   4130 O  O    . TYR B 1 172 ? 123.069 120.139 118.648 1.00 52.88  ? 172 TYR B O    1 
ATOM   4131 C  CB   . TYR B 1 172 ? 121.454 119.963 115.738 1.00 52.88  ? 172 TYR B CB   1 
ATOM   4132 C  CG   . TYR B 1 172 ? 120.321 119.293 116.436 1.00 52.88  ? 172 TYR B CG   1 
ATOM   4133 C  CD1  . TYR B 1 172 ? 119.117 119.941 116.602 1.00 52.88  ? 172 TYR B CD1  1 
ATOM   4134 C  CD2  . TYR B 1 172 ? 120.455 118.020 116.938 1.00 52.88  ? 172 TYR B CD2  1 
ATOM   4135 C  CE1  . TYR B 1 172 ? 118.073 119.338 117.243 1.00 52.88  ? 172 TYR B CE1  1 
ATOM   4136 C  CE2  . TYR B 1 172 ? 119.417 117.407 117.580 1.00 52.88  ? 172 TYR B CE2  1 
ATOM   4137 C  CZ   . TYR B 1 172 ? 118.227 118.071 117.729 1.00 52.88  ? 172 TYR B CZ   1 
ATOM   4138 O  OH   . TYR B 1 172 ? 117.183 117.464 118.374 1.00 52.88  ? 172 TYR B OH   1 
ATOM   4139 N  N    . CYS B 1 173 ? 124.383 120.049 116.808 1.00 63.49  ? 173 CYS B N    1 
ATOM   4140 C  CA   . CYS B 1 173 ? 125.486 119.428 117.529 1.00 63.49  ? 173 CYS B CA   1 
ATOM   4141 C  C    . CYS B 1 173 ? 125.885 120.268 118.726 1.00 63.49  ? 173 CYS B C    1 
ATOM   4142 O  O    . CYS B 1 173 ? 126.090 119.731 119.819 1.00 63.49  ? 173 CYS B O    1 
ATOM   4143 C  CB   . CYS B 1 173 ? 126.680 119.216 116.611 1.00 63.49  ? 173 CYS B CB   1 
ATOM   4144 S  SG   . CYS B 1 173 ? 126.507 117.822 115.501 1.00 63.49  ? 173 CYS B SG   1 
ATOM   4145 N  N    . ALA B 1 174 ? 125.917 121.593 118.553 1.00 63.47  ? 174 ALA B N    1 
ATOM   4146 C  CA   . ALA B 1 174 ? 126.264 122.463 119.667 1.00 63.47  ? 174 ALA B CA   1 
ATOM   4147 C  C    . ALA B 1 174 ? 125.315 122.239 120.828 1.00 63.47  ? 174 ALA B C    1 
ATOM   4148 O  O    . ALA B 1 174 ? 125.747 121.928 121.943 1.00 63.47  ? 174 ALA B O    1 
ATOM   4149 C  CB   . ALA B 1 174 ? 126.245 123.922 119.225 1.00 63.47  ? 174 ALA B CB   1 
ATOM   4150 N  N    . HIS B 1 175 ? 124.012 122.278 120.556 1.00 59.78  ? 175 HIS B N    1 
ATOM   4151 C  CA   . HIS B 1 175 ? 123.076 122.043 121.643 1.00 59.78  ? 175 HIS B CA   1 
ATOM   4152 C  C    . HIS B 1 175 ? 123.133 120.600 122.106 1.00 59.78  ? 175 HIS B C    1 
ATOM   4153 O  O    . HIS B 1 175 ? 122.988 120.334 123.306 1.00 59.78  ? 175 HIS B O    1 
ATOM   4154 C  CB   . HIS B 1 175 ? 121.672 122.445 121.226 1.00 59.78  ? 175 HIS B CB   1 
ATOM   4155 C  CG   . HIS B 1 175 ? 121.353 123.864 121.552 1.00 59.78  ? 175 HIS B CG   1 
ATOM   4156 N  ND1  . HIS B 1 175 ? 121.183 124.301 122.845 1.00 59.78  ? 175 HIS B ND1  1 
ATOM   4157 C  CD2  . HIS B 1 175 ? 121.197 124.949 120.762 1.00 59.78  ? 175 HIS B CD2  1 
ATOM   4158 C  CE1  . HIS B 1 175 ? 120.922 125.594 122.838 1.00 59.78  ? 175 HIS B CE1  1 
ATOM   4159 N  NE2  . HIS B 1 175 ? 120.925 126.013 121.586 1.00 59.78  ? 175 HIS B NE2  1 
ATOM   4160 N  N    . TRP B 1 176 ? 123.429 119.674 121.192 1.00 65.98  ? 176 TRP B N    1 
ATOM   4161 C  CA   . TRP B 1 176 ? 123.643 118.291 121.590 1.00 65.98  ? 176 TRP B CA   1 
ATOM   4162 C  C    . TRP B 1 176 ? 124.770 118.203 122.601 1.00 65.98  ? 176 TRP B C    1 
ATOM   4163 O  O    . TRP B 1 176 ? 124.650 117.504 123.615 1.00 65.98  ? 176 TRP B O    1 
ATOM   4164 C  CB   . TRP B 1 176 ? 123.951 117.446 120.359 1.00 65.98  ? 176 TRP B CB   1 
ATOM   4165 C  CG   . TRP B 1 176 ? 123.666 116.008 120.520 1.00 65.98  ? 176 TRP B CG   1 
ATOM   4166 C  CD1  . TRP B 1 176 ? 123.069 115.408 121.576 1.00 65.98  ? 176 TRP B CD1  1 
ATOM   4167 C  CD2  . TRP B 1 176 ? 123.958 114.976 119.581 1.00 65.98  ? 176 TRP B CD2  1 
ATOM   4168 N  NE1  . TRP B 1 176 ? 122.968 114.060 121.358 1.00 65.98  ? 176 TRP B NE1  1 
ATOM   4169 C  CE2  . TRP B 1 176 ? 123.510 113.770 120.136 1.00 65.98  ? 176 TRP B CE2  1 
ATOM   4170 C  CE3  . TRP B 1 176 ? 124.557 114.955 118.322 1.00 65.98  ? 176 TRP B CE3  1 
ATOM   4171 C  CZ2  . TRP B 1 176 ? 123.642 112.558 119.480 1.00 65.98  ? 176 TRP B CZ2  1 
ATOM   4172 C  CZ3  . TRP B 1 176 ? 124.689 113.752 117.673 1.00 65.98  ? 176 TRP B CZ3  1 
ATOM   4173 C  CH2  . TRP B 1 176 ? 124.235 112.568 118.251 1.00 65.98  ? 176 TRP B CH2  1 
ATOM   4174 N  N    . GLN B 1 177 ? 125.840 118.971 122.371 1.00 74.99  ? 177 GLN B N    1 
ATOM   4175 C  CA   . GLN B 1 177 ? 126.937 119.053 123.327 1.00 74.99  ? 177 GLN B CA   1 
ATOM   4176 C  C    . GLN B 1 177 ? 126.425 119.454 124.696 1.00 74.99  ? 177 GLN B C    1 
ATOM   4177 O  O    . GLN B 1 177 ? 126.699 118.780 125.699 1.00 74.99  ? 177 GLN B O    1 
ATOM   4178 C  CB   . GLN B 1 177 ? 127.970 120.055 122.825 1.00 74.99  ? 177 GLN B CB   1 
ATOM   4179 C  CG   . GLN B 1 177 ? 129.357 119.824 123.335 1.00 74.99  ? 177 GLN B CG   1 
ATOM   4180 C  CD   . GLN B 1 177 ? 129.703 120.719 124.501 1.00 74.99  ? 177 GLN B CD   1 
ATOM   4181 O  OE1  . GLN B 1 177 ? 129.099 121.774 124.690 1.00 74.99  ? 177 GLN B OE1  1 
ATOM   4182 N  NE2  . GLN B 1 177 ? 130.680 120.302 125.295 1.00 74.99  ? 177 GLN B NE2  1 
ATOM   4183 N  N    . THR B 1 178 ? 125.604 120.507 124.740 1.00 74.10  ? 178 THR B N    1 
ATOM   4184 C  CA   . THR B 1 178 ? 125.070 120.979 126.010 1.00 74.10  ? 178 THR B CA   1 
ATOM   4185 C  C    . THR B 1 178 ? 124.245 119.896 126.683 1.00 74.10  ? 178 THR B C    1 
ATOM   4186 O  O    . THR B 1 178 ? 124.330 119.709 127.904 1.00 74.10  ? 178 THR B O    1 
ATOM   4187 C  CB   . THR B 1 178 ? 124.239 122.238 125.781 1.00 74.10  ? 178 THR B CB   1 
ATOM   4188 O  OG1  . THR B 1 178 ? 125.068 123.252 125.207 1.00 74.10  ? 178 THR B OG1  1 
ATOM   4189 C  CG2  . THR B 1 178 ? 123.679 122.745 127.084 1.00 74.10  ? 178 THR B CG2  1 
ATOM   4190 N  N    . TYR B 1 179 ? 123.524 119.104 125.887 1.00 73.43  ? 179 TYR B N    1 
ATOM   4191 C  CA   . TYR B 1 179 ? 122.663 118.074 126.446 1.00 73.43  ? 179 TYR B CA   1 
ATOM   4192 C  C    . TYR B 1 179 ? 123.437 117.006 127.191 1.00 73.43  ? 179 TYR B C    1 
ATOM   4193 O  O    . TYR B 1 179 ? 122.850 116.301 128.015 1.00 73.43  ? 179 TYR B O    1 
ATOM   4194 C  CB   . TYR B 1 179 ? 121.833 117.427 125.347 1.00 73.43  ? 179 TYR B CB   1 
ATOM   4195 C  CG   . TYR B 1 179 ? 120.713 116.571 125.865 1.00 73.43  ? 179 TYR B CG   1 
ATOM   4196 C  CD1  . TYR B 1 179 ? 119.686 117.118 126.605 1.00 73.43  ? 179 TYR B CD1  1 
ATOM   4197 C  CD2  . TYR B 1 179 ? 120.687 115.216 125.615 1.00 73.43  ? 179 TYR B CD2  1 
ATOM   4198 C  CE1  . TYR B 1 179 ? 118.662 116.334 127.077 1.00 73.43  ? 179 TYR B CE1  1 
ATOM   4199 C  CE2  . TYR B 1 179 ? 119.669 114.428 126.076 1.00 73.43  ? 179 TYR B CE2  1 
ATOM   4200 C  CZ   . TYR B 1 179 ? 118.665 114.988 126.811 1.00 73.43  ? 179 TYR B CZ   1 
ATOM   4201 O  OH   . TYR B 1 179 ? 117.647 114.194 127.272 1.00 73.43  ? 179 TYR B OH   1 
ATOM   4202 N  N    . VAL B 1 180 ? 124.736 116.865 126.941 1.00 78.51  ? 180 VAL B N    1 
ATOM   4203 C  CA   . VAL B 1 180 ? 125.515 115.888 127.683 1.00 78.51  ? 180 VAL B CA   1 
ATOM   4204 C  C    . VAL B 1 180 ? 126.560 116.552 128.559 1.00 78.51  ? 180 VAL B C    1 
ATOM   4205 O  O    . VAL B 1 180 ? 127.418 115.865 129.119 1.00 78.51  ? 180 VAL B O    1 
ATOM   4206 C  CB   . VAL B 1 180 ? 126.150 114.852 126.748 1.00 78.51  ? 180 VAL B CB   1 
ATOM   4207 C  CG1  . VAL B 1 180 ? 125.067 114.088 126.021 1.00 78.51  ? 180 VAL B CG1  1 
ATOM   4208 C  CG2  . VAL B 1 180 ? 127.073 115.533 125.776 1.00 78.51  ? 180 VAL B CG2  1 
ATOM   4209 N  N    . SER B 1 181 ? 126.518 117.875 128.690 1.00 82.36  ? 181 SER B N    1 
ATOM   4210 C  CA   . SER B 1 181 ? 127.418 118.535 129.628 1.00 82.36  ? 181 SER B CA   1 
ATOM   4211 C  C    . SER B 1 181 ? 126.760 119.606 130.473 1.00 82.36  ? 181 SER B C    1 
ATOM   4212 O  O    . SER B 1 181 ? 127.372 120.045 131.450 1.00 82.36  ? 181 SER B O    1 
ATOM   4213 C  CB   . SER B 1 181 ? 128.606 119.156 128.895 1.00 82.36  ? 181 SER B CB   1 
ATOM   4214 O  OG   . SER B 1 181 ? 129.518 119.714 129.822 1.00 82.36  ? 181 SER B OG   1 
ATOM   4215 N  N    . GLY B 1 182 ? 125.559 120.065 130.137 1.00 87.76  ? 182 GLY B N    1 
ATOM   4216 C  CA   . GLY B 1 182 ? 124.894 121.083 130.916 1.00 87.76  ? 182 GLY B CA   1 
ATOM   4217 C  C    . GLY B 1 182 ? 125.481 122.468 130.790 1.00 87.76  ? 182 GLY B C    1 
ATOM   4218 O  O    . GLY B 1 182 ? 124.970 123.397 131.419 1.00 87.76  ? 182 GLY B O    1 
ATOM   4219 N  N    . MET B 1 183 ? 126.531 122.636 129.991 1.00 96.43  ? 183 MET B N    1 
ATOM   4220 C  CA   . MET B 1 183 ? 127.205 123.912 129.834 1.00 96.43  ? 183 MET B CA   1 
ATOM   4221 C  C    . MET B 1 183 ? 127.666 124.043 128.394 1.00 96.43  ? 183 MET B C    1 
ATOM   4222 O  O    . MET B 1 183 ? 128.142 123.074 127.798 1.00 96.43  ? 183 MET B O    1 
ATOM   4223 C  CB   . MET B 1 183 ? 128.398 124.035 130.790 1.00 96.43  ? 183 MET B CB   1 
ATOM   4224 C  CG   . MET B 1 183 ? 129.202 122.754 130.933 1.00 96.43  ? 183 MET B CG   1 
ATOM   4225 S  SD   . MET B 1 183 ? 130.797 123.003 131.739 1.00 96.43  ? 183 MET B SD   1 
ATOM   4226 C  CE   . MET B 1 183 ? 131.861 123.263 130.324 1.00 96.43  ? 183 MET B CE   1 
ATOM   4227 N  N    . LEU B 1 184 ? 127.526 125.241 127.842 1.00 99.37  ? 184 LEU B N    1 
ATOM   4228 C  CA   . LEU B 1 184 ? 127.836 125.465 126.438 1.00 99.37  ? 184 LEU B CA   1 
ATOM   4229 C  C    . LEU B 1 184 ? 129.337 125.665 126.277 1.00 99.37  ? 184 LEU B C    1 
ATOM   4230 O  O    . LEU B 1 184 ? 129.904 126.606 126.842 1.00 99.37  ? 184 LEU B O    1 
ATOM   4231 C  CB   . LEU B 1 184 ? 127.074 126.676 125.905 1.00 99.37  ? 184 LEU B CB   1 
ATOM   4232 C  CG   . LEU B 1 184 ? 125.591 126.550 125.541 1.00 99.37  ? 184 LEU B CG   1 
ATOM   4233 C  CD1  . LEU B 1 184 ? 124.706 126.512 126.778 1.00 99.37  ? 184 LEU B CD1  1 
ATOM   4234 C  CD2  . LEU B 1 184 ? 125.162 127.682 124.621 1.00 99.37  ? 184 LEU B CD2  1 
ATOM   4235 N  N    . ARG B 1 185 ? 129.977 124.780 125.524 1.00 101.12 ? 185 ARG B N    1 
ATOM   4236 C  CA   . ARG B 1 185 ? 131.377 124.925 125.155 1.00 101.12 ? 185 ARG B CA   1 
ATOM   4237 C  C    . ARG B 1 185 ? 131.429 125.458 123.732 1.00 101.12 ? 185 ARG B C    1 
ATOM   4238 O  O    . ARG B 1 185 ? 130.863 124.846 122.821 1.00 101.12 ? 185 ARG B O    1 
ATOM   4239 C  CB   . ARG B 1 185 ? 132.122 123.596 125.268 1.00 101.12 ? 185 ARG B CB   1 
ATOM   4240 C  CG   . ARG B 1 185 ? 132.459 123.198 126.691 1.00 101.12 ? 185 ARG B CG   1 
ATOM   4241 C  CD   . ARG B 1 185 ? 133.237 121.890 126.742 1.00 101.12 ? 185 ARG B CD   1 
ATOM   4242 N  NE   . ARG B 1 185 ? 134.559 122.018 126.137 1.00 101.12 ? 185 ARG B NE   1 
ATOM   4243 C  CZ   . ARG B 1 185 ? 135.700 121.887 126.801 1.00 101.12 ? 185 ARG B CZ   1 
ATOM   4244 N  NH1  . ARG B 1 185 ? 135.688 121.625 128.099 1.00 101.12 ? 185 ARG B NH1  1 
ATOM   4245 N  NH2  . ARG B 1 185 ? 136.858 122.022 126.169 1.00 101.12 ? 185 ARG B NH2  1 
ATOM   4246 N  N    . PHE B 1 186 ? 132.090 126.597 123.543 1.00 101.27 ? 186 PHE B N    1 
ATOM   4247 C  CA   . PHE B 1 186 ? 132.079 127.229 122.229 1.00 101.27 ? 186 PHE B CA   1 
ATOM   4248 C  C    . PHE B 1 186 ? 133.109 126.608 121.295 1.00 101.27 ? 186 PHE B C    1 
ATOM   4249 O  O    . PHE B 1 186 ? 132.756 126.010 120.272 1.00 101.27 ? 186 PHE B O    1 
ATOM   4250 C  CB   . PHE B 1 186 ? 132.318 128.730 122.372 1.00 101.27 ? 186 PHE B CB   1 
ATOM   4251 C  CG   . PHE B 1 186 ? 131.095 129.500 122.780 1.00 101.27 ? 186 PHE B CG   1 
ATOM   4252 C  CD1  . PHE B 1 186 ? 129.841 128.922 122.719 1.00 101.27 ? 186 PHE B CD1  1 
ATOM   4253 C  CD2  . PHE B 1 186 ? 131.196 130.817 123.196 1.00 101.27 ? 186 PHE B CD2  1 
ATOM   4254 C  CE1  . PHE B 1 186 ? 128.718 129.633 123.079 1.00 101.27 ? 186 PHE B CE1  1 
ATOM   4255 C  CE2  . PHE B 1 186 ? 130.074 131.530 123.560 1.00 101.27 ? 186 PHE B CE2  1 
ATOM   4256 C  CZ   . PHE B 1 186 ? 128.836 130.937 123.502 1.00 101.27 ? 186 PHE B CZ   1 
ATOM   4257 N  N    . GLY B 1 187 ? 134.381 126.727 121.635 1.00 101.59 ? 187 GLY B N    1 
ATOM   4258 C  CA   . GLY B 1 187 ? 135.458 126.279 120.778 1.00 101.59 ? 187 GLY B CA   1 
ATOM   4259 C  C    . GLY B 1 187 ? 136.227 127.444 120.179 1.00 101.59 ? 187 GLY B C    1 
ATOM   4260 O  O    . GLY B 1 187 ? 135.820 128.605 120.243 1.00 101.59 ? 187 GLY B O    1 
ATOM   4261 N  N    . LYS B 1 188 ? 137.366 127.097 119.574 1.00 102.97 ? 188 LYS B N    1 
ATOM   4262 C  CA   . LYS B 1 188 ? 138.289 128.100 119.059 1.00 102.97 ? 188 LYS B CA   1 
ATOM   4263 C  C    . LYS B 1 188 ? 137.761 128.810 117.823 1.00 102.97 ? 188 LYS B C    1 
ATOM   4264 O  O    . LYS B 1 188 ? 138.247 129.898 117.496 1.00 102.97 ? 188 LYS B O    1 
ATOM   4265 C  CB   . LYS B 1 188 ? 139.641 127.445 118.774 1.00 102.97 ? 188 LYS B CB   1 
ATOM   4266 C  CG   . LYS B 1 188 ? 140.483 127.227 120.020 1.00 102.97 ? 188 LYS B CG   1 
ATOM   4267 C  CD   . LYS B 1 188 ? 141.380 126.007 119.893 1.00 102.97 ? 188 LYS B CD   1 
ATOM   4268 C  CE   . LYS B 1 188 ? 141.785 125.476 121.260 1.00 102.97 ? 188 LYS B CE   1 
ATOM   4269 N  NZ   . LYS B 1 188 ? 142.051 124.012 121.249 1.00 102.97 ? 188 LYS B NZ   1 
ATOM   4270 N  N    . VAL B 1 189 ? 136.792 128.227 117.131 1.00 97.05  ? 189 VAL B N    1 
ATOM   4271 C  CA   . VAL B 1 189 ? 136.105 128.906 116.043 1.00 97.05  ? 189 VAL B CA   1 
ATOM   4272 C  C    . VAL B 1 189 ? 134.612 128.698 116.271 1.00 97.05  ? 189 VAL B C    1 
ATOM   4273 O  O    . VAL B 1 189 ? 134.178 127.585 116.592 1.00 97.05  ? 189 VAL B O    1 
ATOM   4274 C  CB   . VAL B 1 189 ? 136.576 128.406 114.661 1.00 97.05  ? 189 VAL B CB   1 
ATOM   4275 C  CG1  . VAL B 1 189 ? 135.454 127.826 113.825 1.00 97.05  ? 189 VAL B CG1  1 
ATOM   4276 C  CG2  . VAL B 1 189 ? 137.289 129.521 113.915 1.00 97.05  ? 189 VAL B CG2  1 
ATOM   4277 N  N    . ASP B 1 190 ? 133.848 129.776 116.214 1.00 95.45  ? 190 ASP B N    1 
ATOM   4278 C  CA   . ASP B 1 190 ? 132.466 129.711 116.666 1.00 95.45  ? 190 ASP B CA   1 
ATOM   4279 C  C    . ASP B 1 190 ? 131.649 130.777 115.938 1.00 95.45  ? 190 ASP B C    1 
ATOM   4280 O  O    . ASP B 1 190 ? 132.026 131.239 114.855 1.00 95.45  ? 190 ASP B O    1 
ATOM   4281 C  CB   . ASP B 1 190 ? 132.385 129.847 118.195 1.00 95.45  ? 190 ASP B CB   1 
ATOM   4282 C  CG   . ASP B 1 190 ? 131.112 129.248 118.758 1.00 95.45  ? 190 ASP B CG   1 
ATOM   4283 O  OD1  . ASP B 1 190 ? 130.533 128.364 118.092 1.00 95.45  ? 190 ASP B OD1  1 
ATOM   4284 O  OD2  . ASP B 1 190 ? 130.664 129.696 119.823 1.00 95.45  ? 190 ASP B OD2  1 
ATOM   4285 N  N    . VAL B 1 191 ? 130.523 131.151 116.546 1.00 86.50  ? 191 VAL B N    1 
ATOM   4286 C  CA   . VAL B 1 191 ? 129.449 131.892 115.893 1.00 86.50  ? 191 VAL B CA   1 
ATOM   4287 C  C    . VAL B 1 191 ? 129.935 133.234 115.375 1.00 86.50  ? 191 VAL B C    1 
ATOM   4288 O  O    . VAL B 1 191 ? 129.501 133.696 114.314 1.00 86.50  ? 191 VAL B O    1 
ATOM   4289 C  CB   . VAL B 1 191 ? 128.286 132.076 116.878 1.00 86.50  ? 191 VAL B CB   1 
ATOM   4290 C  CG1  . VAL B 1 191 ? 127.083 132.660 116.183 1.00 86.50  ? 191 VAL B CG1  1 
ATOM   4291 C  CG2  . VAL B 1 191 ? 127.965 130.767 117.534 1.00 86.50  ? 191 VAL B CG2  1 
ATOM   4292 N  N    . THR B 1 192 ? 130.818 133.892 116.125 1.00 92.87  ? 192 THR B N    1 
ATOM   4293 C  CA   . THR B 1 192 ? 131.294 135.206 115.711 1.00 92.87  ? 192 THR B CA   1 
ATOM   4294 C  C    . THR B 1 192 ? 132.065 135.128 114.398 1.00 92.87  ? 192 THR B C    1 
ATOM   4295 O  O    . THR B 1 192 ? 131.946 136.019 113.548 1.00 92.87  ? 192 THR B O    1 
ATOM   4296 C  CB   . THR B 1 192 ? 132.147 135.816 116.813 1.00 92.87  ? 192 THR B CB   1 
ATOM   4297 O  OG1  . THR B 1 192 ? 133.261 134.957 117.084 1.00 92.87  ? 192 THR B OG1  1 
ATOM   4298 C  CG2  . THR B 1 192 ? 131.316 135.984 118.071 1.00 92.87  ? 192 THR B CG2  1 
ATOM   4299 N  N    . GLU B 1 193 ? 132.843 134.059 114.207 1.00 95.69  ? 193 GLU B N    1 
ATOM   4300 C  CA   . GLU B 1 193 ? 133.569 133.881 112.954 1.00 95.69  ? 193 GLU B CA   1 
ATOM   4301 C  C    . GLU B 1 193 ? 132.618 133.720 111.772 1.00 95.69  ? 193 GLU B C    1 
ATOM   4302 O  O    . GLU B 1 193 ? 132.815 134.346 110.726 1.00 95.69  ? 193 GLU B O    1 
ATOM   4303 C  CB   . GLU B 1 193 ? 134.506 132.679 113.064 1.00 95.69  ? 193 GLU B CB   1 
ATOM   4304 C  CG   . GLU B 1 193 ? 135.766 132.960 113.861 1.00 95.69  ? 193 GLU B CG   1 
ATOM   4305 C  CD   . GLU B 1 193 ? 135.549 132.836 115.354 1.00 95.69  ? 193 GLU B CD   1 
ATOM   4306 O  OE1  . GLU B 1 193 ? 134.419 132.513 115.769 1.00 95.69  ? 193 GLU B OE1  1 
ATOM   4307 O  OE2  . GLU B 1 193 ? 136.513 133.062 116.120 1.00 95.69  ? 193 GLU B OE2  1 
ATOM   4308 N  N    . ILE B 1 194 ? 131.577 132.898 111.925 1.00 86.88  ? 194 ILE B N    1 
ATOM   4309 C  CA   . ILE B 1 194 ? 130.600 132.737 110.852 1.00 86.88  ? 194 ILE B CA   1 
ATOM   4310 C  C    . ILE B 1 194 ? 129.892 134.050 110.575 1.00 86.88  ? 194 ILE B C    1 
ATOM   4311 O  O    . ILE B 1 194 ? 129.670 134.422 109.420 1.00 86.88  ? 194 ILE B O    1 
ATOM   4312 C  CB   . ILE B 1 194 ? 129.585 131.635 111.190 1.00 86.88  ? 194 ILE B CB   1 
ATOM   4313 C  CG1  . ILE B 1 194 ? 130.268 130.290 111.297 1.00 86.88  ? 194 ILE B CG1  1 
ATOM   4314 C  CG2  . ILE B 1 194 ? 128.500 131.563 110.137 1.00 86.88  ? 194 ILE B CG2  1 
ATOM   4315 C  CD1  . ILE B 1 194 ? 129.362 129.256 111.839 1.00 86.88  ? 194 ILE B CD1  1 
ATOM   4316 N  N    . GLN B 1 195 ? 129.503 134.761 111.629 1.00 86.45  ? 195 GLN B N    1 
ATOM   4317 C  CA   . GLN B 1 195 ? 128.741 135.984 111.434 1.00 86.45  ? 195 GLN B CA   1 
ATOM   4318 C  C    . GLN B 1 195 ? 129.574 137.051 110.733 1.00 86.45  ? 195 GLN B C    1 
ATOM   4319 O  O    . GLN B 1 195 ? 129.079 137.726 109.819 1.00 86.45  ? 195 GLN B O    1 
ATOM   4320 C  CB   . GLN B 1 195 ? 128.205 136.481 112.774 1.00 86.45  ? 195 GLN B CB   1 
ATOM   4321 C  CG   . GLN B 1 195 ? 126.937 135.755 113.207 1.00 86.45  ? 195 GLN B CG   1 
ATOM   4322 C  CD   . GLN B 1 195 ? 126.679 135.844 114.699 1.00 86.45  ? 195 GLN B CD   1 
ATOM   4323 O  OE1  . GLN B 1 195 ? 127.540 136.270 115.464 1.00 86.45  ? 195 GLN B OE1  1 
ATOM   4324 N  NE2  . GLN B 1 195 ? 125.486 135.444 115.114 1.00 86.45  ? 195 GLN B NE2  1 
ATOM   4325 N  N    . ILE B 1 196 ? 130.848 137.199 111.108 1.00 86.53  ? 196 ILE B N    1 
ATOM   4326 C  CA   . ILE B 1 196 ? 131.677 138.178 110.414 1.00 86.53  ? 196 ILE B CA   1 
ATOM   4327 C  C    . ILE B 1 196 ? 131.969 137.718 108.988 1.00 86.53  ? 196 ILE B C    1 
ATOM   4328 O  O    . ILE B 1 196 ? 132.006 138.535 108.064 1.00 86.53  ? 196 ILE B O    1 
ATOM   4329 C  CB   . ILE B 1 196 ? 132.966 138.500 111.196 1.00 86.53  ? 196 ILE B CB   1 
ATOM   4330 C  CG1  . ILE B 1 196 ? 133.891 137.291 111.304 1.00 86.53  ? 196 ILE B CG1  1 
ATOM   4331 C  CG2  . ILE B 1 196 ? 132.624 139.057 112.566 1.00 86.53  ? 196 ILE B CG2  1 
ATOM   4332 C  CD1  . ILE B 1 196 ? 135.334 137.651 111.576 1.00 86.53  ? 196 ILE B CD1  1 
ATOM   4333 N  N    . ALA B 1 197 ? 132.142 136.410 108.773 1.00 84.02  ? 197 ALA B N    1 
ATOM   4334 C  CA   . ALA B 1 197 ? 132.373 135.926 107.417 1.00 84.02  ? 197 ALA B CA   1 
ATOM   4335 C  C    . ALA B 1 197 ? 131.158 136.166 106.532 1.00 84.02  ? 197 ALA B C    1 
ATOM   4336 O  O    . ALA B 1 197 ? 131.297 136.508 105.352 1.00 84.02  ? 197 ALA B O    1 
ATOM   4337 C  CB   . ALA B 1 197 ? 132.735 134.444 107.443 1.00 84.02  ? 197 ALA B CB   1 
ATOM   4338 N  N    . LEU B 1 198 ? 129.963 136.015 107.087 1.00 82.97  ? 198 LEU B N    1 
ATOM   4339 C  CA   . LEU B 1 198 ? 128.763 136.208 106.293 1.00 82.97  ? 198 LEU B CA   1 
ATOM   4340 C  C    . LEU B 1 198 ? 128.477 137.677 106.045 1.00 82.97  ? 198 LEU B C    1 
ATOM   4341 O  O    . LEU B 1 198 ? 127.992 138.027 104.965 1.00 82.97  ? 198 LEU B O    1 
ATOM   4342 C  CB   . LEU B 1 198 ? 127.572 135.518 106.951 1.00 82.97  ? 198 LEU B CB   1 
ATOM   4343 C  CG   . LEU B 1 198 ? 127.681 133.991 106.897 1.00 82.97  ? 198 LEU B CG   1 
ATOM   4344 C  CD1  . LEU B 1 198 ? 126.365 133.325 107.220 1.00 82.97  ? 198 LEU B CD1  1 
ATOM   4345 C  CD2  . LEU B 1 198 ? 128.204 133.515 105.553 1.00 82.97  ? 198 LEU B CD2  1 
ATOM   4346 N  N    . VAL B 1 199 ? 128.789 138.562 106.993 1.00 81.43  ? 199 VAL B N    1 
ATOM   4347 C  CA   . VAL B 1 199 ? 128.626 139.972 106.650 1.00 81.43  ? 199 VAL B CA   1 
ATOM   4348 C  C    . VAL B 1 199 ? 129.692 140.386 105.639 1.00 81.43  ? 199 VAL B C    1 
ATOM   4349 O  O    . VAL B 1 199 ? 129.441 141.252 104.792 1.00 81.43  ? 199 VAL B O    1 
ATOM   4350 C  CB   . VAL B 1 199 ? 128.612 140.867 107.907 1.00 81.43  ? 199 VAL B CB   1 
ATOM   4351 C  CG1  . VAL B 1 199 ? 129.937 140.855 108.625 1.00 81.43  ? 199 VAL B CG1  1 
ATOM   4352 C  CG2  . VAL B 1 199 ? 128.185 142.286 107.556 1.00 81.43  ? 199 VAL B CG2  1 
ATOM   4353 N  N    . ILE B 1 200 ? 130.865 139.739 105.663 1.00 84.07  ? 200 ILE B N    1 
ATOM   4354 C  CA   . ILE B 1 200 ? 131.880 139.997 104.641 1.00 84.07  ? 200 ILE B CA   1 
ATOM   4355 C  C    . ILE B 1 200 ? 131.393 139.554 103.264 1.00 84.07  ? 200 ILE B C    1 
ATOM   4356 O  O    . ILE B 1 200 ? 131.530 140.289 102.280 1.00 84.07  ? 200 ILE B O    1 
ATOM   4357 C  CB   . ILE B 1 200 ? 133.212 139.323 105.016 1.00 84.07  ? 200 ILE B CB   1 
ATOM   4358 C  CG1  . ILE B 1 200 ? 133.927 140.119 106.104 1.00 84.07  ? 200 ILE B CG1  1 
ATOM   4359 C  CG2  . ILE B 1 200 ? 134.114 139.171 103.806 1.00 84.07  ? 200 ILE B CG2  1 
ATOM   4360 C  CD1  . ILE B 1 200 ? 135.108 139.397 106.701 1.00 84.07  ? 200 ILE B CD1  1 
ATOM   4361 N  N    . VAL B 1 201 ? 130.811 138.353 103.169 1.00 84.19  ? 201 VAL B N    1 
ATOM   4362 C  CA   . VAL B 1 201 ? 130.357 137.896 101.855 1.00 84.19  ? 201 VAL B CA   1 
ATOM   4363 C  C    . VAL B 1 201 ? 129.178 138.740 101.388 1.00 84.19  ? 201 VAL B C    1 
ATOM   4364 O  O    . VAL B 1 201 ? 129.046 139.026 100.191 1.00 84.19  ? 201 VAL B O    1 
ATOM   4365 C  CB   . VAL B 1 201 ? 130.032 136.384 101.853 1.00 84.19  ? 201 VAL B CB   1 
ATOM   4366 C  CG1  . VAL B 1 201 ? 128.878 136.049 102.735 1.00 84.19  ? 201 VAL B CG1  1 
ATOM   4367 C  CG2  . VAL B 1 201 ? 129.734 135.900 100.463 1.00 84.19  ? 201 VAL B CG2  1 
ATOM   4368 N  N    . PHE B 1 202 ? 128.348 139.214 102.316 1.00 82.81  ? 202 PHE B N    1 
ATOM   4369 C  CA   . PHE B 1 202 ? 127.248 140.093 101.945 1.00 82.81  ? 202 PHE B CA   1 
ATOM   4370 C  C    . PHE B 1 202 ? 127.759 141.416 101.388 1.00 82.81  ? 202 PHE B C    1 
ATOM   4371 O  O    . PHE B 1 202 ? 127.319 141.856 100.322 1.00 82.81  ? 202 PHE B O    1 
ATOM   4372 C  CB   . PHE B 1 202 ? 126.352 140.334 103.150 1.00 82.81  ? 202 PHE B CB   1 
ATOM   4373 C  CG   . PHE B 1 202 ? 125.201 139.391 103.243 1.00 82.81  ? 202 PHE B CG   1 
ATOM   4374 C  CD1  . PHE B 1 202 ? 125.399 138.036 103.110 1.00 82.81  ? 202 PHE B CD1  1 
ATOM   4375 C  CD2  . PHE B 1 202 ? 123.921 139.854 103.471 1.00 82.81  ? 202 PHE B CD2  1 
ATOM   4376 C  CE1  . PHE B 1 202 ? 124.351 137.168 103.199 1.00 82.81  ? 202 PHE B CE1  1 
ATOM   4377 C  CE2  . PHE B 1 202 ? 122.871 138.980 103.558 1.00 82.81  ? 202 PHE B CE2  1 
ATOM   4378 C  CZ   . PHE B 1 202 ? 123.084 137.635 103.422 1.00 82.81  ? 202 PHE B CZ   1 
ATOM   4379 N  N    . VAL B 1 203 ? 128.698 142.062 102.088 1.00 88.93  ? 203 VAL B N    1 
ATOM   4380 C  CA   . VAL B 1 203 ? 129.163 143.362 101.610 1.00 88.93  ? 203 VAL B CA   1 
ATOM   4381 C  C    . VAL B 1 203 ? 130.000 143.201 100.349 1.00 88.93  ? 203 VAL B C    1 
ATOM   4382 O  O    . VAL B 1 203 ? 130.059 144.114 99.516  1.00 88.93  ? 203 VAL B O    1 
ATOM   4383 C  CB   . VAL B 1 203 ? 129.940 144.125 102.701 1.00 88.93  ? 203 VAL B CB   1 
ATOM   4384 C  CG1  . VAL B 1 203 ? 129.030 144.459 103.874 1.00 88.93  ? 203 VAL B CG1  1 
ATOM   4385 C  CG2  . VAL B 1 203 ? 131.179 143.367 103.141 1.00 88.93  ? 203 VAL B CG2  1 
ATOM   4386 N  N    . LEU B 1 204 ? 130.642 142.045 100.174 1.00 90.08  ? 204 LEU B N    1 
ATOM   4387 C  CA   . LEU B 1 204 ? 131.415 141.812 98.963  1.00 90.08  ? 204 LEU B CA   1 
ATOM   4388 C  C    . LEU B 1 204 ? 130.491 141.625 97.769  1.00 90.08  ? 204 LEU B C    1 
ATOM   4389 O  O    . LEU B 1 204 ? 130.743 142.171 96.690  1.00 90.08  ? 204 LEU B O    1 
ATOM   4390 C  CB   . LEU B 1 204 ? 132.329 140.601 99.166  1.00 90.08  ? 204 LEU B CB   1 
ATOM   4391 C  CG   . LEU B 1 204 ? 133.593 140.358 98.327  1.00 90.08  ? 204 LEU B CG   1 
ATOM   4392 C  CD1  . LEU B 1 204 ? 134.349 139.176 98.903  1.00 90.08  ? 204 LEU B CD1  1 
ATOM   4393 C  CD2  . LEU B 1 204 ? 133.329 140.117 96.850  1.00 90.08  ? 204 LEU B CD2  1 
ATOM   4394 N  N    . SER B 1 205 ? 129.401 140.876 97.946  1.00 91.32  ? 205 SER B N    1 
ATOM   4395 C  CA   . SER B 1 205 ? 128.435 140.735 96.865  1.00 91.32  ? 205 SER B CA   1 
ATOM   4396 C  C    . SER B 1 205 ? 127.611 142.001 96.673  1.00 91.32  ? 205 SER B C    1 
ATOM   4397 O  O    . SER B 1 205 ? 126.945 142.146 95.644  1.00 91.32  ? 205 SER B O    1 
ATOM   4398 C  CB   . SER B 1 205 ? 127.519 139.543 97.127  1.00 91.32  ? 205 SER B CB   1 
ATOM   4399 O  OG   . SER B 1 205 ? 126.734 139.260 95.987  1.00 91.32  ? 205 SER B OG   1 
ATOM   4400 N  N    . ALA B 1 206 ? 127.635 142.912 97.643  1.00 94.15  ? 206 ALA B N    1 
ATOM   4401 C  CA   . ALA B 1 206 ? 126.938 144.181 97.484  1.00 94.15  ? 206 ALA B CA   1 
ATOM   4402 C  C    . ALA B 1 206 ? 127.776 145.181 96.700  1.00 94.15  ? 206 ALA B C    1 
ATOM   4403 O  O    . ALA B 1 206 ? 127.336 145.696 95.663  1.00 94.15  ? 206 ALA B O    1 
ATOM   4404 C  CB   . ALA B 1 206 ? 126.577 144.755 98.855  1.00 94.15  ? 206 ALA B CB   1 
ATOM   4405 N  N    . PHE B 1 207 ? 128.984 145.479 97.190  1.00 100.92 ? 207 PHE B N    1 
ATOM   4406 C  CA   . PHE B 1 207 ? 129.810 146.519 96.580  1.00 100.92 ? 207 PHE B CA   1 
ATOM   4407 C  C    . PHE B 1 207 ? 130.213 146.144 95.161  1.00 100.92 ? 207 PHE B C    1 
ATOM   4408 O  O    . PHE B 1 207 ? 130.090 146.951 94.235  1.00 100.92 ? 207 PHE B O    1 
ATOM   4409 C  CB   . PHE B 1 207 ? 131.046 146.781 97.440  1.00 100.92 ? 207 PHE B CB   1 
ATOM   4410 C  CG   . PHE B 1 207 ? 130.842 147.840 98.480  1.00 100.92 ? 207 PHE B CG   1 
ATOM   4411 C  CD1  . PHE B 1 207 ? 130.519 149.133 98.113  1.00 100.92 ? 207 PHE B CD1  1 
ATOM   4412 C  CD2  . PHE B 1 207 ? 130.972 147.542 99.826  1.00 100.92 ? 207 PHE B CD2  1 
ATOM   4413 C  CE1  . PHE B 1 207 ? 130.328 150.115 99.070  1.00 100.92 ? 207 PHE B CE1  1 
ATOM   4414 C  CE2  . PHE B 1 207 ? 130.784 148.517 100.786 1.00 100.92 ? 207 PHE B CE2  1 
ATOM   4415 C  CZ   . PHE B 1 207 ? 130.462 149.806 100.409 1.00 100.92 ? 207 PHE B CZ   1 
ATOM   4416 N  N    . GLY B 1 208 ? 130.695 144.922 94.975  1.00 103.22 ? 208 GLY B N    1 
ATOM   4417 C  CA   . GLY B 1 208 ? 130.941 144.414 93.643  1.00 103.22 ? 208 GLY B CA   1 
ATOM   4418 C  C    . GLY B 1 208 ? 129.742 143.666 93.098  1.00 103.22 ? 208 GLY B C    1 
ATOM   4419 O  O    . GLY B 1 208 ? 128.815 143.315 93.823  1.00 103.22 ? 208 GLY B O    1 
ATOM   4420 N  N    . GLY B 1 209 ? 129.763 143.441 91.787  1.00 106.77 ? 209 GLY B N    1 
ATOM   4421 C  CA   . GLY B 1 209 ? 128.732 142.633 91.169  1.00 106.77 ? 209 GLY B CA   1 
ATOM   4422 C  C    . GLY B 1 209 ? 128.811 141.190 91.627  1.00 106.77 ? 209 GLY B C    1 
ATOM   4423 O  O    . GLY B 1 209 ? 129.885 140.647 91.873  1.00 106.77 ? 209 GLY B O    1 
ATOM   4424 N  N    . ALA B 1 210 ? 127.642 140.559 91.750  1.00 103.90 ? 210 ALA B N    1 
ATOM   4425 C  CA   . ALA B 1 210 ? 127.597 139.171 92.189  1.00 103.90 ? 210 ALA B CA   1 
ATOM   4426 C  C    . ALA B 1 210 ? 128.133 138.220 91.127  1.00 103.90 ? 210 ALA B C    1 
ATOM   4427 O  O    . ALA B 1 210 ? 128.487 137.079 91.452  1.00 103.90 ? 210 ALA B O    1 
ATOM   4428 C  CB   . ALA B 1 210 ? 126.171 138.790 92.572  1.00 103.90 ? 210 ALA B CB   1 
ATOM   4429 N  N    . THR B 1 211 ? 128.235 138.677 89.876  1.00 109.92 ? 211 THR B N    1 
ATOM   4430 C  CA   . THR B 1 211 ? 128.747 137.841 88.798  1.00 109.92 ? 211 THR B CA   1 
ATOM   4431 C  C    . THR B 1 211 ? 130.197 137.432 89.009  1.00 109.92 ? 211 THR B C    1 
ATOM   4432 O  O    . THR B 1 211 ? 130.656 136.480 88.368  1.00 109.92 ? 211 THR B O    1 
ATOM   4433 C  CB   . THR B 1 211 ? 128.611 138.574 87.465  1.00 109.92 ? 211 THR B CB   1 
ATOM   4434 O  OG1  . THR B 1 211 ? 129.481 139.714 87.455  1.00 109.92 ? 211 THR B OG1  1 
ATOM   4435 C  CG2  . THR B 1 211 ? 127.180 139.036 87.262  1.00 109.92 ? 211 THR B CG2  1 
ATOM   4436 N  N    . MET B 1 212 ? 130.925 138.119 89.895  1.00 110.27 ? 212 MET B N    1 
ATOM   4437 C  CA   . MET B 1 212 ? 132.280 137.696 90.227  1.00 110.27 ? 212 MET B CA   1 
ATOM   4438 C  C    . MET B 1 212 ? 132.302 136.325 90.878  1.00 110.27 ? 212 MET B C    1 
ATOM   4439 O  O    . MET B 1 212 ? 133.343 135.659 90.856  1.00 110.27 ? 212 MET B O    1 
ATOM   4440 C  CB   . MET B 1 212 ? 132.962 138.754 91.117  1.00 110.27 ? 212 MET B CB   1 
ATOM   4441 C  CG   . MET B 1 212 ? 132.488 138.916 92.583  1.00 110.27 ? 212 MET B CG   1 
ATOM   4442 S  SD   . MET B 1 212 ? 132.728 137.593 93.793  1.00 110.27 ? 212 MET B SD   1 
ATOM   4443 C  CE   . MET B 1 212 ? 134.464 137.786 94.171  1.00 110.27 ? 212 MET B CE   1 
ATOM   4444 N  N    . TRP B 1 213 ? 131.187 135.889 91.464  1.00 104.65 ? 213 TRP B N    1 
ATOM   4445 C  CA   . TRP B 1 213 ? 131.129 134.535 91.991  1.00 104.65 ? 213 TRP B CA   1 
ATOM   4446 C  C    . TRP B 1 213 ? 131.132 133.482 90.895  1.00 104.65 ? 213 TRP B C    1 
ATOM   4447 O  O    . TRP B 1 213 ? 131.337 132.302 91.194  1.00 104.65 ? 213 TRP B O    1 
ATOM   4448 C  CB   . TRP B 1 213 ? 129.899 134.384 92.887  1.00 104.65 ? 213 TRP B CB   1 
ATOM   4449 C  CG   . TRP B 1 213 ? 129.980 135.251 94.101  1.00 104.65 ? 213 TRP B CG   1 
ATOM   4450 C  CD1  . TRP B 1 213 ? 129.285 136.400 94.334  1.00 104.65 ? 213 TRP B CD1  1 
ATOM   4451 C  CD2  . TRP B 1 213 ? 130.803 135.042 95.252  1.00 104.65 ? 213 TRP B CD2  1 
ATOM   4452 N  NE1  . TRP B 1 213 ? 129.628 136.924 95.555  1.00 104.65 ? 213 TRP B NE1  1 
ATOM   4453 C  CE2  . TRP B 1 213 ? 130.559 136.104 96.138  1.00 104.65 ? 213 TRP B CE2  1 
ATOM   4454 C  CE3  . TRP B 1 213 ? 131.724 134.059 95.618  1.00 104.65 ? 213 TRP B CE3  1 
ATOM   4455 C  CZ2  . TRP B 1 213 ? 131.203 136.215 97.359  1.00 104.65 ? 213 TRP B CZ2  1 
ATOM   4456 C  CZ3  . TRP B 1 213 ? 132.356 134.171 96.837  1.00 104.65 ? 213 TRP B CZ3  1 
ATOM   4457 C  CH2  . TRP B 1 213 ? 132.093 135.237 97.693  1.00 104.65 ? 213 TRP B CH2  1 
ATOM   4458 N  N    . ASP B 1 214 ? 130.915 133.868 89.639  1.00 112.99 ? 214 ASP B N    1 
ATOM   4459 C  CA   . ASP B 1 214 ? 131.061 132.956 88.516  1.00 112.99 ? 214 ASP B CA   1 
ATOM   4460 C  C    . ASP B 1 214 ? 132.463 132.965 87.920  1.00 112.99 ? 214 ASP B C    1 
ATOM   4461 O  O    . ASP B 1 214 ? 132.746 132.158 87.030  1.00 112.99 ? 214 ASP B O    1 
ATOM   4462 C  CB   . ASP B 1 214 ? 130.045 133.293 87.419  1.00 112.99 ? 214 ASP B CB   1 
ATOM   4463 C  CG   . ASP B 1 214 ? 128.665 132.745 87.717  1.00 112.99 ? 214 ASP B CG   1 
ATOM   4464 O  OD1  . ASP B 1 214 ? 128.538 131.948 88.668  1.00 112.99 ? 214 ASP B OD1  1 
ATOM   4465 O  OD2  . ASP B 1 214 ? 127.712 133.104 86.995  1.00 112.99 ? 214 ASP B OD2  1 
ATOM   4466 N  N    . TYR B 1 215 ? 133.344 133.845 88.388  1.00 124.29 ? 215 TYR B N    1 
ATOM   4467 C  CA   . TYR B 1 215 ? 134.693 133.940 87.843  1.00 124.29 ? 215 TYR B CA   1 
ATOM   4468 C  C    . TYR B 1 215 ? 135.532 132.809 88.412  1.00 124.29 ? 215 TYR B C    1 
ATOM   4469 O  O    . TYR B 1 215 ? 135.865 132.810 89.602  1.00 124.29 ? 215 TYR B O    1 
ATOM   4470 C  CB   . TYR B 1 215 ? 135.318 135.294 88.170  1.00 124.29 ? 215 TYR B CB   1 
ATOM   4471 C  CG   . TYR B 1 215 ? 136.812 135.337 87.944  1.00 124.29 ? 215 TYR B CG   1 
ATOM   4472 C  CD1  . TYR B 1 215 ? 137.340 135.360 86.659  1.00 124.29 ? 215 TYR B CD1  1 
ATOM   4473 C  CD2  . TYR B 1 215 ? 137.698 135.353 89.015  1.00 124.29 ? 215 TYR B CD2  1 
ATOM   4474 C  CE1  . TYR B 1 215 ? 138.705 135.398 86.445  1.00 124.29 ? 215 TYR B CE1  1 
ATOM   4475 C  CE2  . TYR B 1 215 ? 139.066 135.388 88.810  1.00 124.29 ? 215 TYR B CE2  1 
ATOM   4476 C  CZ   . TYR B 1 215 ? 139.561 135.412 87.523  1.00 124.29 ? 215 TYR B CZ   1 
ATOM   4477 O  OH   . TYR B 1 215 ? 140.919 135.449 87.316  1.00 124.29 ? 215 TYR B OH   1 
ATOM   4478 N  N    . THR B 1 216 ? 135.880 131.843 87.569  1.00 130.51 ? 216 THR B N    1 
ATOM   4479 C  CA   . THR B 1 216 ? 136.691 130.731 88.028  1.00 130.51 ? 216 THR B CA   1 
ATOM   4480 C  C    . THR B 1 216 ? 138.136 131.171 88.234  1.00 130.51 ? 216 THR B C    1 
ATOM   4481 O  O    . THR B 1 216 ? 138.583 132.202 87.721  1.00 130.51 ? 216 THR B O    1 
ATOM   4482 C  CB   . THR B 1 216 ? 136.636 129.571 87.035  1.00 130.51 ? 216 THR B CB   1 
ATOM   4483 O  OG1  . THR B 1 216 ? 137.304 128.434 87.592  1.00 130.51 ? 216 THR B OG1  1 
ATOM   4484 C  CG2  . THR B 1 216 ? 137.306 129.953 85.729  1.00 130.51 ? 216 THR B CG2  1 
ATOM   4485 N  N    . ILE B 1 217 ? 138.866 130.386 89.017  1.00 135.36 ? 217 ILE B N    1 
ATOM   4486 C  CA   . ILE B 1 217 ? 140.288 130.632 89.219  1.00 135.36 ? 217 ILE B CA   1 
ATOM   4487 C  C    . ILE B 1 217 ? 141.067 129.927 88.114  1.00 135.36 ? 217 ILE B C    1 
ATOM   4488 O  O    . ILE B 1 217 ? 140.815 128.747 87.830  1.00 135.36 ? 217 ILE B O    1 
ATOM   4489 C  CB   . ILE B 1 217 ? 140.752 130.176 90.612  1.00 135.36 ? 217 ILE B CB   1 
ATOM   4490 C  CG1  . ILE B 1 217 ? 140.254 128.764 90.924  1.00 135.36 ? 217 ILE B CG1  1 
ATOM   4491 C  CG2  . ILE B 1 217 ? 140.267 131.150 91.670  1.00 135.36 ? 217 ILE B CG2  1 
ATOM   4492 C  CD1  . ILE B 1 217 ? 140.990 128.109 92.068  1.00 135.36 ? 217 ILE B CD1  1 
ATOM   4493 N  N    . PRO B 1 218 ? 141.998 130.608 87.446  1.00 138.67 ? 218 PRO B N    1 
ATOM   4494 C  CA   . PRO B 1 218 ? 142.792 129.931 86.410  1.00 138.67 ? 218 PRO B CA   1 
ATOM   4495 C  C    . PRO B 1 218 ? 143.783 128.927 86.969  1.00 138.67 ? 218 PRO B C    1 
ATOM   4496 O  O    . PRO B 1 218 ? 144.349 128.145 86.195  1.00 138.67 ? 218 PRO B O    1 
ATOM   4497 C  CB   . PRO B 1 218 ? 143.507 131.089 85.704  1.00 138.67 ? 218 PRO B CB   1 
ATOM   4498 C  CG   . PRO B 1 218 ? 143.599 132.153 86.746  1.00 138.67 ? 218 PRO B CG   1 
ATOM   4499 C  CD   . PRO B 1 218 ? 142.356 132.031 87.579  1.00 138.67 ? 218 PRO B CD   1 
ATOM   4500 N  N    . ILE B 1 219 ? 144.017 128.928 88.282  1.00 143.78 ? 219 ILE B N    1 
ATOM   4501 C  CA   . ILE B 1 219 ? 144.987 128.011 88.872  1.00 143.78 ? 219 ILE B CA   1 
ATOM   4502 C  C    . ILE B 1 219 ? 144.484 126.573 88.805  1.00 143.78 ? 219 ILE B C    1 
ATOM   4503 O  O    . ILE B 1 219 ? 145.215 125.662 88.400  1.00 143.78 ? 219 ILE B O    1 
ATOM   4504 C  CB   . ILE B 1 219 ? 145.302 128.432 90.319  1.00 143.78 ? 219 ILE B CB   1 
ATOM   4505 C  CG1  . ILE B 1 219 ? 145.732 129.899 90.368  1.00 143.78 ? 219 ILE B CG1  1 
ATOM   4506 C  CG2  . ILE B 1 219 ? 146.375 127.535 90.912  1.00 143.78 ? 219 ILE B CG2  1 
ATOM   4507 C  CD1  . ILE B 1 219 ? 145.896 130.442 91.771  1.00 143.78 ? 219 ILE B CD1  1 
ATOM   4508 N  N    . LEU B 1 220 ? 143.224 126.345 89.196  1.00 139.80 ? 220 LEU B N    1 
ATOM   4509 C  CA   . LEU B 1 220 ? 142.687 124.992 89.280  1.00 139.80 ? 220 LEU B CA   1 
ATOM   4510 C  C    . LEU B 1 220 ? 141.283 124.863 88.702  1.00 139.80 ? 220 LEU B C    1 
ATOM   4511 O  O    . LEU B 1 220 ? 140.641 123.826 88.914  1.00 139.80 ? 220 LEU B O    1 
ATOM   4512 C  CB   . LEU B 1 220 ? 142.688 124.500 90.734  1.00 139.80 ? 220 LEU B CB   1 
ATOM   4513 C  CG   . LEU B 1 220 ? 144.049 124.260 91.393  1.00 139.80 ? 220 LEU B CG   1 
ATOM   4514 C  CD1  . LEU B 1 220 ? 143.884 123.907 92.864  1.00 139.80 ? 220 LEU B CD1  1 
ATOM   4515 C  CD2  . LEU B 1 220 ? 144.819 123.172 90.659  1.00 139.80 ? 220 LEU B CD2  1 
ATOM   4516 N  N    . GLU B 1 221 ? 140.796 125.880 87.984  1.00 137.61 ? 221 GLU B N    1 
ATOM   4517 C  CA   . GLU B 1 221 ? 139.492 125.849 87.310  1.00 137.61 ? 221 GLU B CA   1 
ATOM   4518 C  C    . GLU B 1 221 ? 138.358 125.553 88.293  1.00 137.61 ? 221 GLU B C    1 
ATOM   4519 O  O    . GLU B 1 221 ? 137.535 124.659 88.086  1.00 137.61 ? 221 GLU B O    1 
ATOM   4520 C  CB   . GLU B 1 221 ? 139.494 124.847 86.152  1.00 137.61 ? 221 GLU B CB   1 
ATOM   4521 C  CG   . GLU B 1 221 ? 140.641 125.046 85.176  1.00 137.61 ? 221 GLU B CG   1 
ATOM   4522 C  CD   . GLU B 1 221 ? 140.665 126.440 84.583  1.00 137.61 ? 221 GLU B CD   1 
ATOM   4523 O  OE1  . GLU B 1 221 ? 139.613 126.891 84.082  1.00 137.61 ? 221 GLU B OE1  1 
ATOM   4524 O  OE2  . GLU B 1 221 ? 141.732 127.085 84.619  1.00 137.61 ? 221 GLU B OE2  1 
ATOM   4525 N  N    . ILE B 1 222 ? 138.329 126.315 89.384  1.00 129.65 ? 222 ILE B N    1 
ATOM   4526 C  CA   . ILE B 1 222 ? 137.327 126.170 90.432  1.00 129.65 ? 222 ILE B CA   1 
ATOM   4527 C  C    . ILE B 1 222 ? 136.444 127.407 90.422  1.00 129.65 ? 222 ILE B C    1 
ATOM   4528 O  O    . ILE B 1 222 ? 136.941 128.535 90.323  1.00 129.65 ? 222 ILE B O    1 
ATOM   4529 C  CB   . ILE B 1 222 ? 137.983 125.958 91.806  1.00 129.65 ? 222 ILE B CB   1 
ATOM   4530 C  CG1  . ILE B 1 222 ? 139.012 124.829 91.724  1.00 129.65 ? 222 ILE B CG1  1 
ATOM   4531 C  CG2  . ILE B 1 222 ? 136.940 125.636 92.848  1.00 129.65 ? 222 ILE B CG2  1 
ATOM   4532 C  CD1  . ILE B 1 222 ? 139.630 124.459 93.054  1.00 129.65 ? 222 ILE B CD1  1 
ATOM   4533 N  N    . LYS B 1 223 ? 135.133 127.193 90.554  1.00 117.84 ? 223 LYS B N    1 
ATOM   4534 C  CA   . LYS B 1 223 ? 134.119 128.206 90.282  1.00 117.84 ? 223 LYS B CA   1 
ATOM   4535 C  C    . LYS B 1 223 ? 134.147 129.377 91.262  1.00 117.84 ? 223 LYS B C    1 
ATOM   4536 O  O    . LYS B 1 223 ? 133.472 130.381 91.012  1.00 117.84 ? 223 LYS B O    1 
ATOM   4537 C  CB   . LYS B 1 223 ? 132.743 127.531 90.291  1.00 117.84 ? 223 LYS B CB   1 
ATOM   4538 C  CG   . LYS B 1 223 ? 131.632 128.275 89.577  1.00 117.84 ? 223 LYS B CG   1 
ATOM   4539 C  CD   . LYS B 1 223 ? 131.831 128.249 88.075  1.00 117.84 ? 223 LYS B CD   1 
ATOM   4540 C  CE   . LYS B 1 223 ? 130.531 128.538 87.351  1.00 117.84 ? 223 LYS B CE   1 
ATOM   4541 N  NZ   . LYS B 1 223 ? 129.995 129.878 87.691  1.00 117.84 ? 223 LYS B NZ   1 
ATOM   4542 N  N    . LEU B 1 224 ? 134.894 129.263 92.363  1.00 111.63 ? 224 LEU B N    1 
ATOM   4543 C  CA   . LEU B 1 224 ? 135.100 130.206 93.461  1.00 111.63 ? 224 LEU B CA   1 
ATOM   4544 C  C    . LEU B 1 224 ? 133.894 130.252 94.402  1.00 111.63 ? 224 LEU B C    1 
ATOM   4545 O  O    . LEU B 1 224 ? 134.010 130.791 95.501  1.00 111.63 ? 224 LEU B O    1 
ATOM   4546 C  CB   . LEU B 1 224 ? 135.451 131.635 92.985  1.00 111.63 ? 224 LEU B CB   1 
ATOM   4547 C  CG   . LEU B 1 224 ? 135.796 132.760 93.969  1.00 111.63 ? 224 LEU B CG   1 
ATOM   4548 C  CD1  . LEU B 1 224 ? 137.052 132.417 94.751  1.00 111.63 ? 224 LEU B CD1  1 
ATOM   4549 C  CD2  . LEU B 1 224 ? 135.947 134.089 93.256  1.00 111.63 ? 224 LEU B CD2  1 
ATOM   4550 N  N    . LYS B 1 225 ? 132.768 129.638 94.057  1.00 104.00 ? 225 LYS B N    1 
ATOM   4551 C  CA   . LYS B 1 225 ? 131.737 129.390 95.052  1.00 104.00 ? 225 LYS B CA   1 
ATOM   4552 C  C    . LYS B 1 225 ? 132.069 128.187 95.906  1.00 104.00 ? 225 LYS B C    1 
ATOM   4553 O  O    . LYS B 1 225 ? 131.315 127.865 96.830  1.00 104.00 ? 225 LYS B O    1 
ATOM   4554 C  CB   . LYS B 1 225 ? 130.382 129.177 94.382  1.00 104.00 ? 225 LYS B CB   1 
ATOM   4555 C  CG   . LYS B 1 225 ? 129.922 130.338 93.539  1.00 104.00 ? 225 LYS B CG   1 
ATOM   4556 C  CD   . LYS B 1 225 ? 128.569 130.058 92.937  1.00 104.00 ? 225 LYS B CD   1 
ATOM   4557 C  CE   . LYS B 1 225 ? 128.139 131.190 92.040  1.00 104.00 ? 225 LYS B CE   1 
ATOM   4558 N  NZ   . LYS B 1 225 ? 128.964 131.220 90.811  1.00 104.00 ? 225 LYS B NZ   1 
ATOM   4559 N  N    . ILE B 1 226 ? 133.175 127.517 95.611  1.00 102.21 ? 226 ILE B N    1 
ATOM   4560 C  CA   . ILE B 1 226 ? 133.559 126.271 96.248  1.00 102.21 ? 226 ILE B CA   1 
ATOM   4561 C  C    . ILE B 1 226 ? 134.546 126.558 97.371  1.00 102.21 ? 226 ILE B C    1 
ATOM   4562 O  O    . ILE B 1 226 ? 134.564 125.855 98.385  1.00 102.21 ? 226 ILE B O    1 
ATOM   4563 C  CB   . ILE B 1 226 ? 134.148 125.303 95.203  1.00 102.21 ? 226 ILE B CB   1 
ATOM   4564 C  CG1  . ILE B 1 226 ? 133.237 125.241 93.977  1.00 102.21 ? 226 ILE B CG1  1 
ATOM   4565 C  CG2  . ILE B 1 226 ? 134.321 123.915 95.765  1.00 102.21 ? 226 ILE B CG2  1 
ATOM   4566 C  CD1  . ILE B 1 226 ? 131.863 124.676 94.267  1.00 102.21 ? 226 ILE B CD1  1 
ATOM   4567 N  N    . LEU B 1 227 ? 135.370 127.590 97.201  1.00 98.00  ? 227 LEU B N    1 
ATOM   4568 C  CA   . LEU B 1 227 ? 136.369 127.906 98.220  1.00 98.00  ? 227 LEU B CA   1 
ATOM   4569 C  C    . LEU B 1 227 ? 135.761 128.325 99.560  1.00 98.00  ? 227 LEU B C    1 
ATOM   4570 O  O    . LEU B 1 227 ? 136.161 127.751 100.589 1.00 98.00  ? 227 LEU B O    1 
ATOM   4571 C  CB   . LEU B 1 227 ? 137.344 128.958 97.679  1.00 98.00  ? 227 LEU B CB   1 
ATOM   4572 C  CG   . LEU B 1 227 ? 138.447 129.382 98.646  1.00 98.00  ? 227 LEU B CG   1 
ATOM   4573 C  CD1  . LEU B 1 227 ? 139.298 128.189 99.040  1.00 98.00  ? 227 LEU B CD1  1 
ATOM   4574 C  CD2  . LEU B 1 227 ? 139.303 130.466 98.022  1.00 98.00  ? 227 LEU B CD2  1 
ATOM   4575 N  N    . PRO B 1 228 ? 134.824 129.282 99.641  1.00 91.51  ? 228 PRO B N    1 
ATOM   4576 C  CA   . PRO B 1 228 ? 134.258 129.597 100.960 1.00 91.51  ? 228 PRO B CA   1 
ATOM   4577 C  C    . PRO B 1 228 ? 133.436 128.467 101.542 1.00 91.51  ? 228 PRO B C    1 
ATOM   4578 O  O    . PRO B 1 228 ? 133.462 128.267 102.762 1.00 91.51  ? 228 PRO B O    1 
ATOM   4579 C  CB   . PRO B 1 228 ? 133.399 130.840 100.697 1.00 91.51  ? 228 PRO B CB   1 
ATOM   4580 C  CG   . PRO B 1 228 ? 133.852 131.359 99.396  1.00 91.51  ? 228 PRO B CG   1 
ATOM   4581 C  CD   . PRO B 1 228 ? 134.227 130.154 98.615  1.00 91.51  ? 228 PRO B CD   1 
ATOM   4582 N  N    . VAL B 1 229 ? 132.723 127.705 100.711 1.00 89.77  ? 229 VAL B N    1 
ATOM   4583 C  CA   . VAL B 1 229 ? 131.922 126.623 101.262 1.00 89.77  ? 229 VAL B CA   1 
ATOM   4584 C  C    . VAL B 1 229 ? 132.808 125.482 101.756 1.00 89.77  ? 229 VAL B C    1 
ATOM   4585 O  O    . VAL B 1 229 ? 132.472 124.820 102.740 1.00 89.77  ? 229 VAL B O    1 
ATOM   4586 C  CB   . VAL B 1 229 ? 130.858 126.152 100.251 1.00 89.77  ? 229 VAL B CB   1 
ATOM   4587 C  CG1  . VAL B 1 229 ? 131.462 125.335 99.141  1.00 89.77  ? 229 VAL B CG1  1 
ATOM   4588 C  CG2  . VAL B 1 229 ? 129.793 125.353 100.960 1.00 89.77  ? 229 VAL B CG2  1 
ATOM   4589 N  N    . LEU B 1 230 ? 133.972 125.256 101.140 1.00 92.56  ? 230 LEU B N    1 
ATOM   4590 C  CA   . LEU B 1 230 ? 134.888 124.262 101.692 1.00 92.56  ? 230 LEU B CA   1 
ATOM   4591 C  C    . LEU B 1 230 ? 135.638 124.763 102.914 1.00 92.56  ? 230 LEU B C    1 
ATOM   4592 O  O    . LEU B 1 230 ? 135.953 123.960 103.797 1.00 92.56  ? 230 LEU B O    1 
ATOM   4593 C  CB   . LEU B 1 230 ? 135.869 123.765 100.631 1.00 92.56  ? 230 LEU B CB   1 
ATOM   4594 C  CG   . LEU B 1 230 ? 135.435 122.554 99.798  1.00 92.56  ? 230 LEU B CG   1 
ATOM   4595 C  CD1  . LEU B 1 230 ? 135.335 121.357 100.724 1.00 92.56  ? 230 LEU B CD1  1 
ATOM   4596 C  CD2  . LEU B 1 230 ? 134.104 122.737 99.115  1.00 92.56  ? 230 LEU B CD2  1 
ATOM   4597 N  N    . GLY B 1 231 ? 135.925 126.062 103.002 1.00 89.25  ? 231 GLY B N    1 
ATOM   4598 C  CA   . GLY B 1 231 ? 136.425 126.587 104.262 1.00 89.25  ? 231 GLY B CA   1 
ATOM   4599 C  C    . GLY B 1 231 ? 135.425 126.402 105.387 1.00 89.25  ? 231 GLY B C    1 
ATOM   4600 O  O    . GLY B 1 231 ? 135.777 125.960 106.489 1.00 89.25  ? 231 GLY B O    1 
ATOM   4601 N  N    . PHE B 1 232 ? 134.155 126.703 105.108 1.00 84.55  ? 232 PHE B N    1 
ATOM   4602 C  CA   . PHE B 1 232 ? 133.092 126.482 106.080 1.00 84.55  ? 232 PHE B CA   1 
ATOM   4603 C  C    . PHE B 1 232 ? 132.974 125.010 106.433 1.00 84.55  ? 232 PHE B C    1 
ATOM   4604 O  O    . PHE B 1 232 ? 132.798 124.663 107.602 1.00 84.55  ? 232 PHE B O    1 
ATOM   4605 C  CB   . PHE B 1 232 ? 131.771 127.013 105.526 1.00 84.55  ? 232 PHE B CB   1 
ATOM   4606 C  CG   . PHE B 1 232 ? 130.599 126.803 106.435 1.00 84.55  ? 232 PHE B CG   1 
ATOM   4607 C  CD1  . PHE B 1 232 ? 130.358 127.671 107.484 1.00 84.55  ? 232 PHE B CD1  1 
ATOM   4608 C  CD2  . PHE B 1 232 ? 129.730 125.749 106.235 1.00 84.55  ? 232 PHE B CD2  1 
ATOM   4609 C  CE1  . PHE B 1 232 ? 129.279 127.484 108.319 1.00 84.55  ? 232 PHE B CE1  1 
ATOM   4610 C  CE2  . PHE B 1 232 ? 128.651 125.560 107.068 1.00 84.55  ? 232 PHE B CE2  1 
ATOM   4611 C  CZ   . PHE B 1 232 ? 128.426 126.428 108.109 1.00 84.55  ? 232 PHE B CZ   1 
ATOM   4612 N  N    . LEU B 1 233 ? 133.079 124.130 105.435 1.00 84.50  ? 233 LEU B N    1 
ATOM   4613 C  CA   . LEU B 1 233 ? 132.982 122.699 105.689 1.00 84.50  ? 233 LEU B CA   1 
ATOM   4614 C  C    . LEU B 1 233 ? 134.131 122.209 106.563 1.00 84.50  ? 233 LEU B C    1 
ATOM   4615 O  O    . LEU B 1 233 ? 133.923 121.393 107.466 1.00 84.50  ? 233 LEU B O    1 
ATOM   4616 C  CB   . LEU B 1 233 ? 132.952 121.945 104.363 1.00 84.50  ? 233 LEU B CB   1 
ATOM   4617 C  CG   . LEU B 1 233 ? 132.302 120.566 104.402 1.00 84.50  ? 233 LEU B CG   1 
ATOM   4618 C  CD1  . LEU B 1 233 ? 130.860 120.695 104.848 1.00 84.50  ? 233 LEU B CD1  1 
ATOM   4619 C  CD2  . LEU B 1 233 ? 132.387 119.897 103.046 1.00 84.50  ? 233 LEU B CD2  1 
ATOM   4620 N  N    . GLY B 1 234 ? 135.348 122.696 106.318 1.00 86.69  ? 234 GLY B N    1 
ATOM   4621 C  CA   . GLY B 1 234 ? 136.470 122.316 107.162 1.00 86.69  ? 234 GLY B CA   1 
ATOM   4622 C  C    . GLY B 1 234 ? 136.297 122.777 108.596 1.00 86.69  ? 234 GLY B C    1 
ATOM   4623 O  O    . GLY B 1 234 ? 136.548 122.019 109.542 1.00 86.69  ? 234 GLY B O    1 
ATOM   4624 N  N    . GLY B 1 235 ? 135.854 124.023 108.778 1.00 83.49  ? 235 GLY B N    1 
ATOM   4625 C  CA   . GLY B 1 235 ? 135.549 124.490 110.119 1.00 83.49  ? 235 GLY B CA   1 
ATOM   4626 C  C    . GLY B 1 235 ? 134.448 123.684 110.781 1.00 83.49  ? 235 GLY B C    1 
ATOM   4627 O  O    . GLY B 1 235 ? 134.479 123.457 111.995 1.00 83.49  ? 235 GLY B O    1 
ATOM   4628 N  N    . VAL B 1 236 ? 133.462 123.248 109.995 1.00 80.14  ? 236 VAL B N    1 
ATOM   4629 C  CA   . VAL B 1 236 ? 132.441 122.332 110.492 1.00 80.14  ? 236 VAL B CA   1 
ATOM   4630 C  C    . VAL B 1 236 ? 133.076 121.040 110.971 1.00 80.14  ? 236 VAL B C    1 
ATOM   4631 O  O    . VAL B 1 236 ? 132.676 120.485 111.996 1.00 80.14  ? 236 VAL B O    1 
ATOM   4632 C  CB   . VAL B 1 236 ? 131.384 122.077 109.407 1.00 80.14  ? 236 VAL B CB   1 
ATOM   4633 C  CG1  . VAL B 1 236 ? 130.526 120.886 109.760 1.00 80.14  ? 236 VAL B CG1  1 
ATOM   4634 C  CG2  . VAL B 1 236 ? 130.509 123.293 109.261 1.00 80.14  ? 236 VAL B CG2  1 
ATOM   4635 N  N    . ILE B 1 237 ? 134.075 120.539 110.243 1.00 84.11  ? 237 ILE B N    1 
ATOM   4636 C  CA   . ILE B 1 237 ? 134.752 119.315 110.671 1.00 84.11  ? 237 ILE B CA   1 
ATOM   4637 C  C    . ILE B 1 237 ? 135.435 119.521 112.019 1.00 84.11  ? 237 ILE B C    1 
ATOM   4638 O  O    . ILE B 1 237 ? 135.305 118.692 112.929 1.00 84.11  ? 237 ILE B O    1 
ATOM   4639 C  CB   . ILE B 1 237 ? 135.739 118.827 109.597 1.00 84.11  ? 237 ILE B CB   1 
ATOM   4640 C  CG1  . ILE B 1 237 ? 135.006 118.554 108.290 1.00 84.11  ? 237 ILE B CG1  1 
ATOM   4641 C  CG2  . ILE B 1 237 ? 136.457 117.574 110.060 1.00 84.11  ? 237 ILE B CG2  1 
ATOM   4642 C  CD1  . ILE B 1 237 ? 133.948 117.477 108.406 1.00 84.11  ? 237 ILE B CD1  1 
ATOM   4643 N  N    . PHE B 1 238 ? 136.143 120.646 112.182 1.00 87.03  ? 238 PHE B N    1 
ATOM   4644 C  CA   . PHE B 1 238 ? 136.764 120.935 113.480 1.00 87.03  ? 238 PHE B CA   1 
ATOM   4645 C  C    . PHE B 1 238 ? 135.728 120.998 114.597 1.00 87.03  ? 238 PHE B C    1 
ATOM   4646 O  O    . PHE B 1 238 ? 135.864 120.324 115.628 1.00 87.03  ? 238 PHE B O    1 
ATOM   4647 C  CB   . PHE B 1 238 ? 137.566 122.238 113.456 1.00 87.03  ? 238 PHE B CB   1 
ATOM   4648 C  CG   . PHE B 1 238 ? 138.793 122.199 112.594 1.00 87.03  ? 238 PHE B CG   1 
ATOM   4649 C  CD1  . PHE B 1 238 ? 139.957 121.616 113.066 1.00 87.03  ? 238 PHE B CD1  1 
ATOM   4650 C  CD2  . PHE B 1 238 ? 138.814 122.811 111.355 1.00 87.03  ? 238 PHE B CD2  1 
ATOM   4651 C  CE1  . PHE B 1 238 ? 141.102 121.592 112.290 1.00 87.03  ? 238 PHE B CE1  1 
ATOM   4652 C  CE2  . PHE B 1 238 ? 139.954 122.789 110.572 1.00 87.03  ? 238 PHE B CE2  1 
ATOM   4653 C  CZ   . PHE B 1 238 ? 141.100 122.184 111.043 1.00 87.03  ? 238 PHE B CZ   1 
ATOM   4654 N  N    . SER B 1 239 ? 134.676 121.795 114.403 1.00 84.94  ? 239 SER B N    1 
ATOM   4655 C  CA   . SER B 1 239 ? 133.704 122.006 115.469 1.00 84.94  ? 239 SER B CA   1 
ATOM   4656 C  C    . SER B 1 239 ? 132.917 120.738 115.771 1.00 84.94  ? 239 SER B C    1 
ATOM   4657 O  O    . SER B 1 239 ? 132.604 120.458 116.933 1.00 84.94  ? 239 SER B O    1 
ATOM   4658 C  CB   . SER B 1 239 ? 132.762 123.151 115.104 1.00 84.94  ? 239 SER B CB   1 
ATOM   4659 O  OG   . SER B 1 239 ? 133.382 124.408 115.310 1.00 84.94  ? 239 SER B OG   1 
ATOM   4660 N  N    . CYS B 1 240 ? 132.595 119.948 114.747 1.00 90.02  ? 240 CYS B N    1 
ATOM   4661 C  CA   . CYS B 1 240 ? 131.827 118.736 114.973 1.00 90.02  ? 240 CYS B CA   1 
ATOM   4662 C  C    . CYS B 1 240 ? 132.674 117.654 115.619 1.00 90.02  ? 240 CYS B C    1 
ATOM   4663 O  O    . CYS B 1 240 ? 132.151 116.868 116.414 1.00 90.02  ? 240 CYS B O    1 
ATOM   4664 C  CB   . CYS B 1 240 ? 131.230 118.229 113.662 1.00 90.02  ? 240 CYS B CB   1 
ATOM   4665 S  SG   . CYS B 1 240 ? 132.369 117.278 112.638 1.00 90.02  ? 240 CYS B SG   1 
ATOM   4666 N  N    . SER B 1 241 ? 133.971 117.587 115.311 1.00 86.90  ? 241 SER B N    1 
ATOM   4667 C  CA   . SER B 1 241 ? 134.836 116.678 116.057 1.00 86.90  ? 241 SER B CA   1 
ATOM   4668 C  C    . SER B 1 241 ? 134.937 117.098 117.515 1.00 86.90  ? 241 SER B C    1 
ATOM   4669 O  O    . SER B 1 241 ? 134.869 116.255 118.423 1.00 86.90  ? 241 SER B O    1 
ATOM   4670 C  CB   . SER B 1 241 ? 136.220 116.616 115.418 1.00 86.90  ? 241 SER B CB   1 
ATOM   4671 O  OG   . SER B 1 241 ? 136.969 115.533 115.942 1.00 86.90  ? 241 SER B OG   1 
ATOM   4672 N  N    . ASN B 1 242 ? 135.075 118.406 117.754 1.00 84.09  ? 242 ASN B N    1 
ATOM   4673 C  CA   . ASN B 1 242 ? 135.149 118.918 119.117 1.00 84.09  ? 242 ASN B CA   1 
ATOM   4674 C  C    . ASN B 1 242 ? 133.874 118.601 119.889 1.00 84.09  ? 242 ASN B C    1 
ATOM   4675 O  O    . ASN B 1 242 ? 133.938 118.244 121.070 1.00 84.09  ? 242 ASN B O    1 
ATOM   4676 C  CB   . ASN B 1 242 ? 135.408 120.426 119.072 1.00 84.09  ? 242 ASN B CB   1 
ATOM   4677 C  CG   . ASN B 1 242 ? 135.720 121.024 120.434 1.00 84.09  ? 242 ASN B CG   1 
ATOM   4678 O  OD1  . ASN B 1 242 ? 135.727 120.339 121.453 1.00 84.09  ? 242 ASN B OD1  1 
ATOM   4679 N  ND2  . ASN B 1 242 ? 135.989 122.323 120.448 1.00 84.09  ? 242 ASN B ND2  1 
ATOM   4680 N  N    . TYR B 1 243 ? 132.716 118.712 119.240 1.00 84.16  ? 243 TYR B N    1 
ATOM   4681 C  CA   . TYR B 1 243 ? 131.459 118.341 119.881 1.00 84.16  ? 243 TYR B CA   1 
ATOM   4682 C  C    . TYR B 1 243 ? 131.358 116.835 120.113 1.00 84.16  ? 243 TYR B C    1 
ATOM   4683 O  O    . TYR B 1 243 ? 131.055 116.394 121.224 1.00 84.16  ? 243 TYR B O    1 
ATOM   4684 C  CB   . TYR B 1 243 ? 130.278 118.823 119.037 1.00 84.16  ? 243 TYR B CB   1 
ATOM   4685 C  CG   . TYR B 1 243 ? 130.091 120.317 119.049 1.00 84.16  ? 243 TYR B CG   1 
ATOM   4686 C  CD1  . TYR B 1 243 ? 130.445 121.069 120.156 1.00 84.16  ? 243 TYR B CD1  1 
ATOM   4687 C  CD2  . TYR B 1 243 ? 129.563 120.978 117.951 1.00 84.16  ? 243 TYR B CD2  1 
ATOM   4688 C  CE1  . TYR B 1 243 ? 130.276 122.430 120.171 1.00 84.16  ? 243 TYR B CE1  1 
ATOM   4689 C  CE2  . TYR B 1 243 ? 129.394 122.339 117.958 1.00 84.16  ? 243 TYR B CE2  1 
ATOM   4690 C  CZ   . TYR B 1 243 ? 129.752 123.057 119.071 1.00 84.16  ? 243 TYR B CZ   1 
ATOM   4691 O  OH   . TYR B 1 243 ? 129.587 124.418 119.089 1.00 84.16  ? 243 TYR B OH   1 
ATOM   4692 N  N    . PHE B 1 244 ? 131.622 116.032 119.082 1.00 82.77  ? 244 PHE B N    1 
ATOM   4693 C  CA   . PHE B 1 244 ? 131.411 114.595 119.183 1.00 82.77  ? 244 PHE B CA   1 
ATOM   4694 C  C    . PHE B 1 244 ? 132.347 113.921 120.167 1.00 82.77  ? 244 PHE B C    1 
ATOM   4695 O  O    . PHE B 1 244 ? 131.987 112.869 120.702 1.00 82.77  ? 244 PHE B O    1 
ATOM   4696 C  CB   . PHE B 1 244 ? 131.547 113.943 117.811 1.00 82.77  ? 244 PHE B CB   1 
ATOM   4697 C  CG   . PHE B 1 244 ? 130.387 114.203 116.898 1.00 82.77  ? 244 PHE B CG   1 
ATOM   4698 C  CD1  . PHE B 1 244 ? 129.184 114.655 117.404 1.00 82.77  ? 244 PHE B CD1  1 
ATOM   4699 C  CD2  . PHE B 1 244 ? 130.497 113.989 115.539 1.00 82.77  ? 244 PHE B CD2  1 
ATOM   4700 C  CE1  . PHE B 1 244 ? 128.117 114.882 116.572 1.00 82.77  ? 244 PHE B CE1  1 
ATOM   4701 C  CE2  . PHE B 1 244 ? 129.432 114.222 114.703 1.00 82.77  ? 244 PHE B CE2  1 
ATOM   4702 C  CZ   . PHE B 1 244 ? 128.241 114.670 115.218 1.00 82.77  ? 244 PHE B CZ   1 
ATOM   4703 N  N    . HIS B 1 245 ? 133.520 114.504 120.433 1.00 87.50  ? 245 HIS B N    1 
ATOM   4704 C  CA   . HIS B 1 245 ? 134.410 113.905 121.422 1.00 87.50  ? 245 HIS B CA   1 
ATOM   4705 C  C    . HIS B 1 245 ? 133.744 113.828 122.789 1.00 87.50  ? 245 HIS B C    1 
ATOM   4706 O  O    . HIS B 1 245 ? 133.797 112.791 123.458 1.00 87.50  ? 245 HIS B O    1 
ATOM   4707 C  CB   . HIS B 1 245 ? 135.714 114.692 121.511 1.00 87.50  ? 245 HIS B CB   1 
ATOM   4708 C  CG   . HIS B 1 245 ? 136.734 114.060 122.405 1.00 87.50  ? 245 HIS B CG   1 
ATOM   4709 N  ND1  . HIS B 1 245 ? 136.761 114.270 123.766 1.00 87.50  ? 245 HIS B ND1  1 
ATOM   4710 C  CD2  . HIS B 1 245 ? 137.756 113.215 122.133 1.00 87.50  ? 245 HIS B CD2  1 
ATOM   4711 C  CE1  . HIS B 1 245 ? 137.759 113.586 124.294 1.00 87.50  ? 245 HIS B CE1  1 
ATOM   4712 N  NE2  . HIS B 1 245 ? 138.379 112.937 123.325 1.00 87.50  ? 245 HIS B NE2  1 
ATOM   4713 N  N    . VAL B 1 246 ? 133.068 114.900 123.202 1.00 85.15  ? 246 VAL B N    1 
ATOM   4714 C  CA   . VAL B 1 246 ? 132.367 114.887 124.480 1.00 85.15  ? 246 VAL B CA   1 
ATOM   4715 C  C    . VAL B 1 246 ? 130.952 114.319 124.350 1.00 85.15  ? 246 VAL B C    1 
ATOM   4716 O  O    . VAL B 1 246 ? 130.373 113.891 125.359 1.00 85.15  ? 246 VAL B O    1 
ATOM   4717 C  CB   . VAL B 1 246 ? 132.371 116.302 125.090 1.00 85.15  ? 246 VAL B CB   1 
ATOM   4718 C  CG1  . VAL B 1 246 ? 131.587 117.247 124.243 1.00 85.15  ? 246 VAL B CG1  1 
ATOM   4719 C  CG2  . VAL B 1 246 ? 131.887 116.317 126.538 1.00 85.15  ? 246 VAL B CG2  1 
ATOM   4720 N  N    . ILE B 1 247 ? 130.386 114.273 123.139 1.00 84.27  ? 247 ILE B N    1 
ATOM   4721 C  CA   . ILE B 1 247 ? 129.159 113.501 122.939 1.00 84.27  ? 247 ILE B CA   1 
ATOM   4722 C  C    . ILE B 1 247 ? 129.398 112.033 123.270 1.00 84.27  ? 247 ILE B C    1 
ATOM   4723 O  O    . ILE B 1 247 ? 128.599 111.395 123.968 1.00 84.27  ? 247 ILE B O    1 
ATOM   4724 C  CB   . ILE B 1 247 ? 128.625 113.661 121.503 1.00 84.27  ? 247 ILE B CB   1 
ATOM   4725 C  CG1  . ILE B 1 247 ? 128.211 115.098 121.218 1.00 84.27  ? 247 ILE B CG1  1 
ATOM   4726 C  CG2  . ILE B 1 247 ? 127.443 112.752 121.271 1.00 84.27  ? 247 ILE B CG2  1 
ATOM   4727 C  CD1  . ILE B 1 247 ? 127.076 115.570 122.078 1.00 84.27  ? 247 ILE B CD1  1 
ATOM   4728 N  N    . LEU B 1 248 ? 130.506 111.481 122.789 1.00 89.02  ? 248 LEU B N    1 
ATOM   4729 C  CA   . LEU B 1 248 ? 130.829 110.082 123.025 1.00 89.02  ? 248 LEU B CA   1 
ATOM   4730 C  C    . LEU B 1 248 ? 131.685 109.860 124.264 1.00 89.02  ? 248 LEU B C    1 
ATOM   4731 O  O    . LEU B 1 248 ? 131.977 108.707 124.594 1.00 89.02  ? 248 LEU B O    1 
ATOM   4732 C  CB   . LEU B 1 248 ? 131.539 109.486 121.805 1.00 89.02  ? 248 LEU B CB   1 
ATOM   4733 C  CG   . LEU B 1 248 ? 130.661 108.870 120.712 1.00 89.02  ? 248 LEU B CG   1 
ATOM   4734 C  CD1  . LEU B 1 248 ? 129.837 107.727 121.287 1.00 89.02  ? 248 LEU B CD1  1 
ATOM   4735 C  CD2  . LEU B 1 248 ? 129.768 109.894 120.028 1.00 89.02  ? 248 LEU B CD2  1 
ATOM   4736 N  N    . HIS B 1 249 ? 132.112 110.922 124.950 1.00 90.43  ? 249 HIS B N    1 
ATOM   4737 C  CA   . HIS B 1 249 ? 132.921 110.737 126.147 1.00 90.43  ? 249 HIS B CA   1 
ATOM   4738 C  C    . HIS B 1 249 ? 132.535 111.667 127.291 1.00 90.43  ? 249 HIS B C    1 
ATOM   4739 O  O    . HIS B 1 249 ? 133.380 111.934 128.157 1.00 90.43  ? 249 HIS B O    1 
ATOM   4740 C  CB   . HIS B 1 249 ? 134.401 110.907 125.811 1.00 90.43  ? 249 HIS B CB   1 
ATOM   4741 C  CG   . HIS B 1 249 ? 134.890 109.949 124.774 1.00 90.43  ? 249 HIS B CG   1 
ATOM   4742 N  ND1  . HIS B 1 249 ? 134.741 110.179 123.424 1.00 90.43  ? 249 HIS B ND1  1 
ATOM   4743 C  CD2  . HIS B 1 249 ? 135.507 108.750 124.886 1.00 90.43  ? 249 HIS B CD2  1 
ATOM   4744 C  CE1  . HIS B 1 249 ? 135.255 109.167 122.749 1.00 90.43  ? 249 HIS B CE1  1 
ATOM   4745 N  NE2  . HIS B 1 249 ? 135.726 108.285 123.613 1.00 90.43  ? 249 HIS B NE2  1 
ATOM   4746 N  N    . GLY B 1 250 ? 131.310 112.179 127.323 1.00 94.67  ? 250 GLY B N    1 
ATOM   4747 C  CA   . GLY B 1 250 ? 130.855 112.949 128.462 1.00 94.67  ? 250 GLY B CA   1 
ATOM   4748 C  C    . GLY B 1 250 ? 129.664 112.314 129.153 1.00 94.67  ? 250 GLY B C    1 
ATOM   4749 O  O    . GLY B 1 250 ? 128.558 112.304 128.609 1.00 94.67  ? 250 GLY B O    1 
ATOM   4750 N  N    . GLY B 1 251 ? 129.875 111.786 130.355 1.00 105.58 ? 251 GLY B N    1 
ATOM   4751 C  CA   . GLY B 1 251 ? 128.789 111.199 131.113 1.00 105.58 ? 251 GLY B CA   1 
ATOM   4752 C  C    . GLY B 1 251 ? 128.608 111.892 132.445 1.00 105.58 ? 251 GLY B C    1 
ATOM   4753 O  O    . GLY B 1 251 ? 129.460 111.770 133.332 1.00 105.58 ? 251 GLY B O    1 
ATOM   4754 N  N    . VAL B 1 252 ? 127.503 112.612 132.605 1.00 106.54 ? 252 VAL B N    1 
ATOM   4755 C  CA   . VAL B 1 252 ? 127.274 113.462 133.764 1.00 106.54 ? 252 VAL B CA   1 
ATOM   4756 C  C    . VAL B 1 252 ? 126.177 112.900 134.660 1.00 106.54 ? 252 VAL B C    1 
ATOM   4757 O  O    . VAL B 1 252 ? 126.392 112.687 135.852 1.00 106.54 ? 252 VAL B O    1 
ATOM   4758 C  CB   . VAL B 1 252 ? 126.948 114.907 133.329 1.00 106.54 ? 252 VAL B CB   1 
ATOM   4759 C  CG1  . VAL B 1 252 ? 126.668 115.769 134.545 1.00 106.54 ? 252 VAL B CG1  1 
ATOM   4760 C  CG2  . VAL B 1 252 ? 128.094 115.474 132.515 1.00 106.54 ? 252 VAL B CG2  1 
ATOM   4761 N  N    . GLY B 1 253 ? 124.994 112.656 134.100 1.00 111.09 ? 253 GLY B N    1 
ATOM   4762 C  CA   . GLY B 1 253 ? 123.883 112.180 134.906 1.00 111.09 ? 253 GLY B CA   1 
ATOM   4763 C  C    . GLY B 1 253 ? 124.035 110.756 135.391 1.00 111.09 ? 253 GLY B C    1 
ATOM   4764 O  O    . GLY B 1 253 ? 123.410 110.382 136.387 1.00 111.09 ? 253 GLY B O    1 
ATOM   4765 N  N    . LYS B 1 254 ? 124.854 109.957 134.718 1.00 114.62 ? 254 LYS B N    1 
ATOM   4766 C  CA   . LYS B 1 254 ? 125.085 108.571 135.102 1.00 114.62 ? 254 LYS B CA   1 
ATOM   4767 C  C    . LYS B 1 254 ? 126.516 108.219 134.714 1.00 114.62 ? 254 LYS B C    1 
ATOM   4768 O  O    . LYS B 1 254 ? 127.351 109.108 134.517 1.00 114.62 ? 254 LYS B O    1 
ATOM   4769 C  CB   . LYS B 1 254 ? 124.042 107.644 134.458 1.00 114.62 ? 254 LYS B CB   1 
ATOM   4770 C  CG   . LYS B 1 254 ? 123.580 106.511 135.359 1.00 114.62 ? 254 LYS B CG   1 
ATOM   4771 C  CD   . LYS B 1 254 ? 122.914 107.048 136.614 1.00 114.62 ? 254 LYS B CD   1 
ATOM   4772 C  CE   . LYS B 1 254 ? 121.558 107.661 136.303 1.00 114.62 ? 254 LYS B CE   1 
ATOM   4773 N  NZ   . LYS B 1 254 ? 120.886 108.169 137.531 1.00 114.62 ? 254 LYS B NZ   1 
ATOM   4774 N  N    . ASN B 1 255 ? 126.805 106.919 134.625 1.00 116.98 ? 255 ASN B N    1 
ATOM   4775 C  CA   . ASN B 1 255 ? 128.159 106.475 134.314 1.00 116.98 ? 255 ASN B CA   1 
ATOM   4776 C  C    . ASN B 1 255 ? 128.594 106.944 132.931 1.00 116.98 ? 255 ASN B C    1 
ATOM   4777 O  O    . ASN B 1 255 ? 129.748 107.347 132.743 1.00 116.98 ? 255 ASN B O    1 
ATOM   4778 C  CB   . ASN B 1 255 ? 128.242 104.955 134.423 1.00 116.98 ? 255 ASN B CB   1 
ATOM   4779 C  CG   . ASN B 1 255 ? 127.815 104.449 135.787 1.00 116.98 ? 255 ASN B CG   1 
ATOM   4780 O  OD1  . ASN B 1 255 ? 128.174 105.024 136.813 1.00 116.98 ? 255 ASN B OD1  1 
ATOM   4781 N  ND2  . ASN B 1 255 ? 127.036 103.374 135.801 1.00 116.98 ? 255 ASN B ND2  1 
ATOM   4782 N  N    . GLY B 1 256 ? 127.693 106.901 131.956 1.00 110.54 ? 256 GLY B N    1 
ATOM   4783 C  CA   . GLY B 1 256 ? 128.023 107.390 130.633 1.00 110.54 ? 256 GLY B CA   1 
ATOM   4784 C  C    . GLY B 1 256 ? 126.882 108.068 129.904 1.00 110.54 ? 256 GLY B C    1 
ATOM   4785 O  O    . GLY B 1 256 ? 127.004 108.389 128.719 1.00 110.54 ? 256 GLY B O    1 
ATOM   4786 N  N    . SER B 1 257 ? 125.769 108.301 130.593 1.00 101.95 ? 257 SER B N    1 
ATOM   4787 C  CA   . SER B 1 257 ? 124.575 108.820 129.949 1.00 101.95 ? 257 SER B CA   1 
ATOM   4788 C  C    . SER B 1 257 ? 124.569 110.346 130.006 1.00 101.95 ? 257 SER B C    1 
ATOM   4789 O  O    . SER B 1 257 ? 125.569 110.987 130.341 1.00 101.95 ? 257 SER B O    1 
ATOM   4790 C  CB   . SER B 1 257 ? 123.322 108.243 130.597 1.00 101.95 ? 257 SER B CB   1 
ATOM   4791 O  OG   . SER B 1 257 ? 122.977 108.981 131.753 1.00 101.95 ? 257 SER B OG   1 
ATOM   4792 N  N    . THR B 1 258 ? 123.427 110.940 129.675 1.00 93.37  ? 258 THR B N    1 
ATOM   4793 C  CA   . THR B 1 258 ? 123.285 112.382 129.601 1.00 93.37  ? 258 THR B CA   1 
ATOM   4794 C  C    . THR B 1 258 ? 122.767 112.934 130.928 1.00 93.37  ? 258 THR B C    1 
ATOM   4795 O  O    . THR B 1 258 ? 122.595 112.207 131.908 1.00 93.37  ? 258 THR B O    1 
ATOM   4796 C  CB   . THR B 1 258 ? 122.363 112.759 128.446 1.00 93.37  ? 258 THR B CB   1 
ATOM   4797 O  OG1  . THR B 1 258 ? 122.520 114.148 128.145 1.00 93.37  ? 258 THR B OG1  1 
ATOM   4798 C  CG2  . THR B 1 258 ? 120.906 112.490 128.803 1.00 93.37  ? 258 THR B CG2  1 
ATOM   4799 N  N    . ILE B 1 259 ? 122.504 114.244 130.955 1.00 88.06  ? 259 ILE B N    1 
ATOM   4800 C  CA   . ILE B 1 259 ? 122.079 114.905 132.183 1.00 88.06  ? 259 ILE B CA   1 
ATOM   4801 C  C    . ILE B 1 259 ? 120.679 114.492 132.613 1.00 88.06  ? 259 ILE B C    1 
ATOM   4802 O  O    . ILE B 1 259 ? 120.285 114.750 133.756 1.00 88.06  ? 259 ILE B O    1 
ATOM   4803 C  CB   . ILE B 1 259 ? 122.177 116.432 132.018 1.00 88.06  ? 259 ILE B CB   1 
ATOM   4804 C  CG1  . ILE B 1 259 ? 122.504 117.092 133.355 1.00 88.06  ? 259 ILE B CG1  1 
ATOM   4805 C  CG2  . ILE B 1 259 ? 120.895 116.996 131.442 1.00 88.06  ? 259 ILE B CG2  1 
ATOM   4806 C  CD1  . ILE B 1 259 ? 122.957 118.519 133.224 1.00 88.06  ? 259 ILE B CD1  1 
ATOM   4807 N  N    . ALA B 1 260 ? 119.906 113.851 131.737 1.00 85.07  ? 260 ALA B N    1 
ATOM   4808 C  CA   . ALA B 1 260 ? 118.599 113.325 132.105 1.00 85.07  ? 260 ALA B CA   1 
ATOM   4809 C  C    . ALA B 1 260 ? 118.581 111.802 132.158 1.00 85.07  ? 260 ALA B C    1 
ATOM   4810 O  O    . ALA B 1 260 ? 117.512 111.210 132.332 1.00 85.07  ? 260 ALA B O    1 
ATOM   4811 C  CB   . ALA B 1 260 ? 117.530 113.833 131.136 1.00 85.07  ? 260 ALA B CB   1 
ATOM   4812 N  N    . GLY B 1 261 ? 119.737 111.155 132.014 1.00 86.03  ? 261 GLY B N    1 
ATOM   4813 C  CA   . GLY B 1 261 ? 119.821 109.712 132.031 1.00 86.03  ? 261 GLY B CA   1 
ATOM   4814 C  C    . GLY B 1 261 ? 119.572 109.046 130.696 1.00 86.03  ? 261 GLY B C    1 
ATOM   4815 O  O    . GLY B 1 261 ? 119.775 107.832 130.579 1.00 86.03  ? 261 GLY B O    1 
ATOM   4816 N  N    . THR B 1 262 ? 119.149 109.801 129.690 1.00 83.44  ? 262 THR B N    1 
ATOM   4817 C  CA   . THR B 1 262 ? 118.863 109.247 128.378 1.00 83.44  ? 262 THR B CA   1 
ATOM   4818 C  C    . THR B 1 262 ? 120.171 108.893 127.674 1.00 83.44  ? 262 THR B C    1 
ATOM   4819 O  O    . THR B 1 262 ? 121.221 109.476 127.947 1.00 83.44  ? 262 THR B O    1 
ATOM   4820 C  CB   . THR B 1 262 ? 118.043 110.262 127.577 1.00 83.44  ? 262 THR B CB   1 
ATOM   4821 O  OG1  . THR B 1 262 ? 116.829 110.528 128.281 1.00 83.44  ? 262 THR B OG1  1 
ATOM   4822 C  CG2  . THR B 1 262 ? 117.669 109.743 126.196 1.00 83.44  ? 262 THR B CG2  1 
ATOM   4823 N  N    . SER B 1 263 ? 120.114 107.890 126.799 1.00 85.03  ? 263 SER B N    1 
ATOM   4824 C  CA   . SER B 1 263 ? 121.286 107.487 126.035 1.00 85.03  ? 263 SER B CA   1 
ATOM   4825 C  C    . SER B 1 263 ? 121.810 108.653 125.207 1.00 85.03  ? 263 SER B C    1 
ATOM   4826 O  O    . SER B 1 263 ? 121.040 109.463 124.687 1.00 85.03  ? 263 SER B O    1 
ATOM   4827 C  CB   . SER B 1 263 ? 120.945 106.306 125.129 1.00 85.03  ? 263 SER B CB   1 
ATOM   4828 O  OG   . SER B 1 263 ? 119.821 106.597 124.315 1.00 85.03  ? 263 SER B OG   1 
ATOM   4829 N  N    . VAL B 1 264 ? 123.138 108.740 125.106 1.00 80.06  ? 264 VAL B N    1 
ATOM   4830 C  CA   . VAL B 1 264 ? 123.774 109.901 124.499 1.00 80.06  ? 264 VAL B CA   1 
ATOM   4831 C  C    . VAL B 1 264 ? 123.464 110.022 123.018 1.00 80.06  ? 264 VAL B C    1 
ATOM   4832 O  O    . VAL B 1 264 ? 123.482 111.133 122.478 1.00 80.06  ? 264 VAL B O    1 
ATOM   4833 C  CB   . VAL B 1 264 ? 125.295 109.854 124.728 1.00 80.06  ? 264 VAL B CB   1 
ATOM   4834 C  CG1  . VAL B 1 264 ? 125.601 109.923 126.202 1.00 80.06  ? 264 VAL B CG1  1 
ATOM   4835 C  CG2  . VAL B 1 264 ? 125.887 108.596 124.131 1.00 80.06  ? 264 VAL B CG2  1 
ATOM   4836 N  N    . LEU B 1 265 ? 123.170 108.923 122.344 1.00 78.33  ? 265 LEU B N    1 
ATOM   4837 C  CA   . LEU B 1 265 ? 122.929 108.967 120.913 1.00 78.33  ? 265 LEU B CA   1 
ATOM   4838 C  C    . LEU B 1 265 ? 121.467 109.200 120.566 1.00 78.33  ? 265 LEU B C    1 
ATOM   4839 O  O    . LEU B 1 265 ? 121.134 109.276 119.381 1.00 78.33  ? 265 LEU B O    1 
ATOM   4840 C  CB   . LEU B 1 265 ? 123.419 107.673 120.263 1.00 78.33  ? 265 LEU B CB   1 
ATOM   4841 C  CG   . LEU B 1 265 ? 124.874 107.312 120.566 1.00 78.33  ? 265 LEU B CG   1 
ATOM   4842 C  CD1  . LEU B 1 265 ? 125.301 106.103 119.755 1.00 78.33  ? 265 LEU B CD1  1 
ATOM   4843 C  CD2  . LEU B 1 265 ? 125.796 108.487 120.294 1.00 78.33  ? 265 LEU B CD2  1 
ATOM   4844 N  N    . SER B 1 266 ? 120.592 109.300 121.562 1.00 75.42  ? 266 SER B N    1 
ATOM   4845 C  CA   . SER B 1 266 ? 119.173 109.525 121.287 1.00 75.42  ? 266 SER B CA   1 
ATOM   4846 C  C    . SER B 1 266 ? 118.871 110.854 120.603 1.00 75.42  ? 266 SER B C    1 
ATOM   4847 O  O    . SER B 1 266 ? 118.121 110.843 119.612 1.00 75.42  ? 266 SER B O    1 
ATOM   4848 C  CB   . SER B 1 266 ? 118.365 109.372 122.578 1.00 75.42  ? 266 SER B CB   1 
ATOM   4849 O  OG   . SER B 1 266 ? 116.991 109.633 122.349 1.00 75.42  ? 266 SER B OG   1 
ATOM   4850 N  N    . PRO B 1 267 ? 119.372 112.017 121.056 1.00 67.30  ? 267 PRO B N    1 
ATOM   4851 C  CA   . PRO B 1 267 ? 118.963 113.272 120.406 1.00 67.30  ? 267 PRO B CA   1 
ATOM   4852 C  C    . PRO B 1 267 ? 119.429 113.409 118.976 1.00 67.30  ? 267 PRO B C    1 
ATOM   4853 O  O    . PRO B 1 267 ? 118.851 114.212 118.235 1.00 67.30  ? 267 PRO B O    1 
ATOM   4854 C  CB   . PRO B 1 267 ? 119.596 114.351 121.291 1.00 67.30  ? 267 PRO B CB   1 
ATOM   4855 C  CG   . PRO B 1 267 ? 119.835 113.692 122.563 1.00 67.30  ? 267 PRO B CG   1 
ATOM   4856 C  CD   . PRO B 1 267 ? 120.240 112.312 122.206 1.00 67.30  ? 267 PRO B CD   1 
ATOM   4857 N  N    . GLY B 1 268 ? 120.445 112.658 118.558 1.00 64.50  ? 268 GLY B N    1 
ATOM   4858 C  CA   . GLY B 1 268 ? 120.859 112.704 117.170 1.00 64.50  ? 268 GLY B CA   1 
ATOM   4859 C  C    . GLY B 1 268 ? 119.816 112.179 116.211 1.00 64.50  ? 268 GLY B C    1 
ATOM   4860 O  O    . GLY B 1 268 ? 119.850 112.533 115.030 1.00 64.50  ? 268 GLY B O    1 
ATOM   4861 N  N    . LEU B 1 269 ? 118.884 111.354 116.698 1.00 64.47  ? 269 LEU B N    1 
ATOM   4862 C  CA   . LEU B 1 269 ? 117.848 110.797 115.839 1.00 64.47  ? 269 LEU B CA   1 
ATOM   4863 C  C    . LEU B 1 269 ? 116.956 111.873 115.248 1.00 64.47  ? 269 LEU B C    1 
ATOM   4864 O  O    . LEU B 1 269 ? 116.499 111.732 114.110 1.00 64.47  ? 269 LEU B O    1 
ATOM   4865 C  CB   . LEU B 1 269 ? 116.993 109.794 116.608 1.00 64.47  ? 269 LEU B CB   1 
ATOM   4866 C  CG   . LEU B 1 269 ? 117.400 108.328 116.531 1.00 64.47  ? 269 LEU B CG   1 
ATOM   4867 C  CD1  . LEU B 1 269 ? 118.654 108.069 117.339 1.00 64.47  ? 269 LEU B CD1  1 
ATOM   4868 C  CD2  . LEU B 1 269 ? 116.258 107.456 117.020 1.00 64.47  ? 269 LEU B CD2  1 
ATOM   4869 N  N    . HIS B 1 270 ? 116.690 112.946 115.994 1.00 61.20  ? 270 HIS B N    1 
ATOM   4870 C  CA   . HIS B 1 270 ? 115.822 114.003 115.487 1.00 61.20  ? 270 HIS B CA   1 
ATOM   4871 C  C    . HIS B 1 270 ? 116.424 114.675 114.259 1.00 61.20  ? 270 HIS B C    1 
ATOM   4872 O  O    . HIS B 1 270 ? 115.783 114.760 113.197 1.00 61.20  ? 270 HIS B O    1 
ATOM   4873 C  CB   . HIS B 1 270 ? 115.578 115.035 116.579 1.00 61.20  ? 270 HIS B CB   1 
ATOM   4874 C  CG   . HIS B 1 270 ? 114.662 114.570 117.662 1.00 61.20  ? 270 HIS B CG   1 
ATOM   4875 N  ND1  . HIS B 1 270 ? 114.913 114.797 118.997 1.00 61.20  ? 270 HIS B ND1  1 
ATOM   4876 C  CD2  . HIS B 1 270 ? 113.485 113.908 117.607 1.00 61.20  ? 270 HIS B CD2  1 
ATOM   4877 C  CE1  . HIS B 1 270 ? 113.935 114.283 119.718 1.00 61.20  ? 270 HIS B CE1  1 
ATOM   4878 N  NE2  . HIS B 1 270 ? 113.056 113.736 118.900 1.00 61.20  ? 270 HIS B NE2  1 
ATOM   4879 N  N    . ILE B 1 271 ? 117.667 115.140 114.374 1.00 54.28  ? 271 ILE B N    1 
ATOM   4880 C  CA   . ILE B 1 271 ? 118.272 115.824 113.243 1.00 54.28  ? 271 ILE B CA   1 
ATOM   4881 C  C    . ILE B 1 271 ? 118.613 114.831 112.146 1.00 54.28  ? 271 ILE B C    1 
ATOM   4882 O  O    . ILE B 1 271 ? 118.612 115.187 110.961 1.00 54.28  ? 271 ILE B O    1 
ATOM   4883 C  CB   . ILE B 1 271 ? 119.496 116.645 113.686 1.00 54.28  ? 271 ILE B CB   1 
ATOM   4884 C  CG1  . ILE B 1 271 ? 119.804 117.702 112.637 1.00 54.28  ? 271 ILE B CG1  1 
ATOM   4885 C  CG2  . ILE B 1 271 ? 120.701 115.761 113.921 1.00 54.28  ? 271 ILE B CG2  1 
ATOM   4886 C  CD1  . ILE B 1 271 ? 118.621 118.585 112.327 1.00 54.28  ? 271 ILE B CD1  1 
ATOM   4887 N  N    . GLY B 1 272 ? 118.860 113.567 112.502 1.00 54.88  ? 272 GLY B N    1 
ATOM   4888 C  CA   . GLY B 1 272 ? 119.049 112.557 111.481 1.00 54.88  ? 272 GLY B CA   1 
ATOM   4889 C  C    . GLY B 1 272 ? 117.798 112.342 110.657 1.00 54.88  ? 272 GLY B C    1 
ATOM   4890 O  O    . GLY B 1 272 ? 117.863 112.256 109.431 1.00 54.88  ? 272 GLY B O    1 
ATOM   4891 N  N    . LEU B 1 273 ? 116.642 112.283 111.315 1.00 50.66  ? 273 LEU B N    1 
ATOM   4892 C  CA   . LEU B 1 273 ? 115.393 112.103 110.589 1.00 50.66  ? 273 LEU B CA   1 
ATOM   4893 C  C    . LEU B 1 273 ? 115.092 113.315 109.721 1.00 50.66  ? 273 LEU B C    1 
ATOM   4894 O  O    . LEU B 1 273 ? 114.626 113.163 108.586 1.00 50.66  ? 273 LEU B O    1 
ATOM   4895 C  CB   . LEU B 1 273 ? 114.255 111.826 111.568 1.00 50.66  ? 273 LEU B CB   1 
ATOM   4896 C  CG   . LEU B 1 273 ? 112.949 111.261 111.006 1.00 50.66  ? 273 LEU B CG   1 
ATOM   4897 C  CD1  . LEU B 1 273 ? 112.311 110.354 112.028 1.00 50.66  ? 273 LEU B CD1  1 
ATOM   4898 C  CD2  . LEU B 1 273 ? 111.978 112.351 110.628 1.00 50.66  ? 273 LEU B CD2  1 
ATOM   4899 N  N    . ILE B 1 274 ? 115.365 114.522 110.223 1.00 47.65  ? 274 ILE B N    1 
ATOM   4900 C  CA   . ILE B 1 274 ? 115.115 115.718 109.415 1.00 47.65  ? 274 ILE B CA   1 
ATOM   4901 C  C    . ILE B 1 274 ? 116.005 115.731 108.177 1.00 47.65  ? 274 ILE B C    1 
ATOM   4902 O  O    . ILE B 1 274 ? 115.534 115.962 107.055 1.00 47.65  ? 274 ILE B O    1 
ATOM   4903 C  CB   . ILE B 1 274 ? 115.301 116.989 110.255 1.00 47.65  ? 274 ILE B CB   1 
ATOM   4904 C  CG1  . ILE B 1 274 ? 114.059 117.252 111.091 1.00 47.65  ? 274 ILE B CG1  1 
ATOM   4905 C  CG2  . ILE B 1 274 ? 115.542 118.181 109.367 1.00 47.65  ? 274 ILE B CG2  1 
ATOM   4906 C  CD1  . ILE B 1 274 ? 114.159 118.504 111.913 1.00 47.65  ? 274 ILE B CD1  1 
ATOM   4907 N  N    . ILE B 1 275 ? 117.299 115.454 108.351 1.00 47.11  ? 275 ILE B N    1 
ATOM   4908 C  CA   . ILE B 1 275 ? 118.213 115.486 107.214 1.00 47.11  ? 275 ILE B CA   1 
ATOM   4909 C  C    . ILE B 1 275 ? 117.897 114.364 106.231 1.00 47.11  ? 275 ILE B C    1 
ATOM   4910 O  O    . ILE B 1 275 ? 117.957 114.558 105.013 1.00 47.11  ? 275 ILE B O    1 
ATOM   4911 C  CB   . ILE B 1 275 ? 119.669 115.439 107.708 1.00 47.11  ? 275 ILE B CB   1 
ATOM   4912 C  CG1  . ILE B 1 275 ? 120.109 116.834 108.132 1.00 47.11  ? 275 ILE B CG1  1 
ATOM   4913 C  CG2  . ILE B 1 275 ? 120.604 114.918 106.638 1.00 47.11  ? 275 ILE B CG2  1 
ATOM   4914 C  CD1  . ILE B 1 275 ? 121.506 116.881 108.673 1.00 47.11  ? 275 ILE B CD1  1 
ATOM   4915 N  N    . ILE B 1 276 ? 117.510 113.192 106.732 1.00 44.56  ? 276 ILE B N    1 
ATOM   4916 C  CA   . ILE B 1 276 ? 117.183 112.081 105.847 1.00 44.56  ? 276 ILE B CA   1 
ATOM   4917 C  C    . ILE B 1 276 ? 115.907 112.367 105.057 1.00 44.56  ? 276 ILE B C    1 
ATOM   4918 O  O    . ILE B 1 276 ? 115.821 112.057 103.859 1.00 44.56  ? 276 ILE B O    1 
ATOM   4919 C  CB   . ILE B 1 276 ? 117.100 110.781 106.662 1.00 44.56  ? 276 ILE B CB   1 
ATOM   4920 C  CG1  . ILE B 1 276 ? 118.503 110.310 107.030 1.00 44.56  ? 276 ILE B CG1  1 
ATOM   4921 C  CG2  . ILE B 1 276 ? 116.407 109.703 105.906 1.00 44.56  ? 276 ILE B CG2  1 
ATOM   4922 C  CD1  . ILE B 1 276 ? 119.363 110.004 105.842 1.00 44.56  ? 276 ILE B CD1  1 
ATOM   4923 N  N    . LEU B 1 277 ? 114.907 112.981 105.694 1.00 42.44  ? 277 LEU B N    1 
ATOM   4924 C  CA   . LEU B 1 277 ? 113.721 113.388 104.950 1.00 42.44  ? 277 LEU B CA   1 
ATOM   4925 C  C    . LEU B 1 277 ? 114.066 114.423 103.889 1.00 42.44  ? 277 LEU B C    1 
ATOM   4926 O  O    . LEU B 1 277 ? 113.526 114.387 102.776 1.00 42.44  ? 277 LEU B O    1 
ATOM   4927 C  CB   . LEU B 1 277 ? 112.653 113.938 105.888 1.00 42.44  ? 277 LEU B CB   1 
ATOM   4928 C  CG   . LEU B 1 277 ? 111.781 112.913 106.600 1.00 42.44  ? 277 LEU B CG   1 
ATOM   4929 C  CD1  . LEU B 1 277 ? 110.652 113.611 107.315 1.00 42.44  ? 277 LEU B CD1  1 
ATOM   4930 C  CD2  . LEU B 1 277 ? 111.245 111.919 105.609 1.00 42.44  ? 277 LEU B CD2  1 
ATOM   4931 N  N    . ALA B 1 278 ? 114.963 115.353 104.214 1.00 44.58  ? 278 ALA B N    1 
ATOM   4932 C  CA   . ALA B 1 278 ? 115.379 116.337 103.221 1.00 44.58  ? 278 ALA B CA   1 
ATOM   4933 C  C    . ALA B 1 278 ? 116.084 115.677 102.045 1.00 44.58  ? 278 ALA B C    1 
ATOM   4934 O  O    . ALA B 1 278 ? 115.860 116.053 100.891 1.00 44.58  ? 278 ALA B O    1 
ATOM   4935 C  CB   . ALA B 1 278 ? 116.276 117.384 103.864 1.00 44.58  ? 278 ALA B CB   1 
ATOM   4936 N  N    . ILE B 1 279 ? 116.927 114.678 102.317 1.00 43.22  ? 279 ILE B N    1 
ATOM   4937 C  CA   . ILE B 1 279 ? 117.607 113.954 101.243 1.00 43.22  ? 279 ILE B CA   1 
ATOM   4938 C  C    . ILE B 1 279 ? 116.602 113.250 100.340 1.00 43.22  ? 279 ILE B C    1 
ATOM   4939 O  O    . ILE B 1 279 ? 116.696 113.328 99.106  1.00 43.22  ? 279 ILE B O    1 
ATOM   4940 C  CB   . ILE B 1 279 ? 118.625 112.959 101.820 1.00 43.22  ? 279 ILE B CB   1 
ATOM   4941 C  CG1  . ILE B 1 279 ? 119.743 113.681 102.555 1.00 43.22  ? 279 ILE B CG1  1 
ATOM   4942 C  CG2  . ILE B 1 279 ? 119.217 112.113 100.722 1.00 43.22  ? 279 ILE B CG2  1 
ATOM   4943 C  CD1  . ILE B 1 279 ? 120.564 114.535 101.670 1.00 43.22  ? 279 ILE B CD1  1 
ATOM   4944 N  N    . MET B 1 280 ? 115.627 112.549 100.929 1.00 45.27  ? 280 MET B N    1 
ATOM   4945 C  CA   . MET B 1 280 ? 114.650 111.854 100.093 1.00 45.27  ? 280 MET B CA   1 
ATOM   4946 C  C    . MET B 1 280 ? 113.817 112.822 99.261  1.00 45.27  ? 280 MET B C    1 
ATOM   4947 O  O    . MET B 1 280 ? 113.601 112.594 98.066  1.00 45.27  ? 280 MET B O    1 
ATOM   4948 C  CB   . MET B 1 280 ? 113.729 110.944 100.905 1.00 45.27  ? 280 MET B CB   1 
ATOM   4949 C  CG   . MET B 1 280 ? 114.371 109.743 101.551 1.00 45.27  ? 280 MET B CG   1 
ATOM   4950 S  SD   . MET B 1 280 ? 113.301 109.057 102.821 1.00 45.27  ? 280 MET B SD   1 
ATOM   4951 C  CE   . MET B 1 280 ? 114.402 107.892 103.598 1.00 45.27  ? 280 MET B CE   1 
ATOM   4952 N  N    . ILE B 1 281 ? 113.335 113.909 99.861  1.00 42.07  ? 281 ILE B N    1 
ATOM   4953 C  CA   . ILE B 1 281 ? 112.464 114.782 99.082  1.00 42.07  ? 281 ILE B CA   1 
ATOM   4954 C  C    . ILE B 1 281 ? 113.268 115.568 98.048  1.00 42.07  ? 281 ILE B C    1 
ATOM   4955 O  O    . ILE B 1 281 ? 112.737 115.940 96.996  1.00 42.07  ? 281 ILE B O    1 
ATOM   4956 C  CB   . ILE B 1 281 ? 111.644 115.686 100.013 1.00 42.07  ? 281 ILE B CB   1 
ATOM   4957 C  CG1  . ILE B 1 281 ? 110.876 114.826 101.001 1.00 42.07  ? 281 ILE B CG1  1 
ATOM   4958 C  CG2  . ILE B 1 281 ? 110.623 116.476 99.242  1.00 42.07  ? 281 ILE B CG2  1 
ATOM   4959 C  CD1  . ILE B 1 281 ? 110.126 115.618 102.019 1.00 42.07  ? 281 ILE B CD1  1 
ATOM   4960 N  N    . TYR B 1 282 ? 114.556 115.801 98.297  1.00 50.19  ? 282 TYR B N    1 
ATOM   4961 C  CA   . TYR B 1 282 ? 115.439 116.268 97.235  1.00 50.19  ? 282 TYR B CA   1 
ATOM   4962 C  C    . TYR B 1 282 ? 115.507 115.285 96.082  1.00 50.19  ? 282 TYR B C    1 
ATOM   4963 O  O    . TYR B 1 282 ? 115.222 115.641 94.934  1.00 50.19  ? 282 TYR B O    1 
ATOM   4964 C  CB   . TYR B 1 282 ? 116.840 116.498 97.788  1.00 50.19  ? 282 TYR B CB   1 
ATOM   4965 C  CG   . TYR B 1 282 ? 117.758 117.250 96.864  1.00 50.19  ? 282 TYR B CG   1 
ATOM   4966 C  CD1  . TYR B 1 282 ? 117.272 118.138 95.921  1.00 50.19  ? 282 TYR B CD1  1 
ATOM   4967 C  CD2  . TYR B 1 282 ? 119.121 117.014 96.894  1.00 50.19  ? 282 TYR B CD2  1 
ATOM   4968 C  CE1  . TYR B 1 282 ? 118.128 118.789 95.062  1.00 50.19  ? 282 TYR B CE1  1 
ATOM   4969 C  CE2  . TYR B 1 282 ? 119.978 117.665 96.047  1.00 50.19  ? 282 TYR B CE2  1 
ATOM   4970 C  CZ   . TYR B 1 282 ? 119.479 118.553 95.134  1.00 50.19  ? 282 TYR B CZ   1 
ATOM   4971 O  OH   . TYR B 1 282 ? 120.344 119.204 94.287  1.00 50.19  ? 282 TYR B OH   1 
ATOM   4972 N  N    . LYS B 1 283 ? 115.874 114.042 96.363  1.00 45.18  ? 283 LYS B N    1 
ATOM   4973 C  CA   . LYS B 1 283 ? 116.284 113.168 95.273  1.00 45.18  ? 283 LYS B CA   1 
ATOM   4974 C  C    . LYS B 1 283 ? 115.093 112.597 94.513  1.00 45.18  ? 283 LYS B C    1 
ATOM   4975 O  O    . LYS B 1 283 ? 115.171 112.400 93.297  1.00 45.18  ? 283 LYS B O    1 
ATOM   4976 C  CB   . LYS B 1 283 ? 117.173 112.053 95.811  1.00 45.18  ? 283 LYS B CB   1 
ATOM   4977 C  CG   . LYS B 1 283 ? 118.570 112.526 96.156  1.00 45.18  ? 283 LYS B CG   1 
ATOM   4978 C  CD   . LYS B 1 283 ? 119.213 113.254 94.993  1.00 45.18  ? 283 LYS B CD   1 
ATOM   4979 C  CE   . LYS B 1 283 ? 120.726 113.243 95.104  1.00 45.18  ? 283 LYS B CE   1 
ATOM   4980 N  NZ   . LYS B 1 283 ? 121.380 113.211 93.767  1.00 45.18  ? 283 LYS B NZ   1 
ATOM   4981 N  N    . LYS B 1 284 ? 113.983 112.337 95.201  1.00 48.45  ? 284 LYS B N    1 
ATOM   4982 C  CA   . LYS B 1 284 ? 112.878 111.626 94.566  1.00 48.45  ? 284 LYS B CA   1 
ATOM   4983 C  C    . LYS B 1 284 ? 112.080 112.518 93.622  1.00 48.45  ? 284 LYS B C    1 
ATOM   4984 O  O    . LYS B 1 284 ? 111.536 112.018 92.632  1.00 48.45  ? 284 LYS B O    1 
ATOM   4985 C  CB   . LYS B 1 284 ? 111.969 111.025 95.639  1.00 48.45  ? 284 LYS B CB   1 
ATOM   4986 C  CG   . LYS B 1 284 ? 110.708 110.329 95.132  1.00 48.45  ? 284 LYS B CG   1 
ATOM   4987 C  CD   . LYS B 1 284 ? 111.012 109.230 94.128  1.00 48.45  ? 284 LYS B CD   1 
ATOM   4988 C  CE   . LYS B 1 284 ? 109.775 108.853 93.323  1.00 48.45  ? 284 LYS B CE   1 
ATOM   4989 N  NZ   . LYS B 1 284 ? 109.236 109.980 92.529  1.00 48.45  ? 284 LYS B NZ   1 
ATOM   4990 N  N    . SER B 1 285 ? 112.026 113.825 93.886  1.00 51.71  ? 285 SER B N    1 
ATOM   4991 C  CA   . SER B 1 285 ? 111.077 114.729 93.235  1.00 51.71  ? 285 SER B CA   1 
ATOM   4992 C  C    . SER B 1 285 ? 111.130 114.683 91.715  1.00 51.71  ? 285 SER B C    1 
ATOM   4993 O  O    . SER B 1 285 ? 112.118 115.104 91.109  1.00 51.71  ? 285 SER B O    1 
ATOM   4994 C  CB   . SER B 1 285 ? 111.317 116.164 93.690  1.00 51.71  ? 285 SER B CB   1 
ATOM   4995 O  OG   . SER B 1 285 ? 110.265 116.998 93.249  1.00 51.71  ? 285 SER B OG   1 
ATOM   4996 N  N    . ALA B 1 286 ? 110.065 114.166 91.099  1.00 61.55  ? 286 ALA B N    1 
ATOM   4997 C  CA   . ALA B 1 286 ? 110.015 114.078 89.644  1.00 61.55  ? 286 ALA B CA   1 
ATOM   4998 C  C    . ALA B 1 286 ? 109.896 115.460 89.022  1.00 61.55  ? 286 ALA B C    1 
ATOM   4999 O  O    . ALA B 1 286 ? 110.647 115.809 88.106  1.00 61.55  ? 286 ALA B O    1 
ATOM   5000 C  CB   . ALA B 1 286 ? 108.853 113.187 89.208  1.00 61.55  ? 286 ALA B CB   1 
ATOM   5001 N  N    . THR B 1 287 ? 108.963 116.263 89.517  1.00 64.59  ? 287 THR B N    1 
ATOM   5002 C  CA   . THR B 1 287 ? 108.961 117.683 89.213  1.00 64.59  ? 287 THR B CA   1 
ATOM   5003 C  C    . THR B 1 287 ? 110.025 118.334 90.081  1.00 64.59  ? 287 THR B C    1 
ATOM   5004 O  O    . THR B 1 287 ? 110.032 118.145 91.301  1.00 64.59  ? 287 THR B O    1 
ATOM   5005 C  CB   . THR B 1 287 ? 107.589 118.293 89.476  1.00 64.59  ? 287 THR B CB   1 
ATOM   5006 O  OG1  . THR B 1 287 ? 106.612 117.643 88.655  1.00 64.59  ? 287 THR B OG1  1 
ATOM   5007 C  CG2  . THR B 1 287 ? 107.596 119.771 89.155  1.00 64.59  ? 287 THR B CG2  1 
ATOM   5008 N  N    . ASP B 1 288 ? 110.938 119.069 89.461  1.00 67.80  ? 288 ASP B N    1 
ATOM   5009 C  CA   . ASP B 1 288 ? 112.050 119.651 90.203  1.00 67.80  ? 288 ASP B CA   1 
ATOM   5010 C  C    . ASP B 1 288 ? 111.544 120.809 91.048  1.00 67.80  ? 288 ASP B C    1 
ATOM   5011 O  O    . ASP B 1 288 ? 111.282 121.898 90.529  1.00 67.80  ? 288 ASP B O    1 
ATOM   5012 C  CB   . ASP B 1 288 ? 113.142 120.105 89.242  1.00 67.80  ? 288 ASP B CB   1 
ATOM   5013 C  CG   . ASP B 1 288 ? 113.836 118.945 88.570  1.00 67.80  ? 288 ASP B CG   1 
ATOM   5014 O  OD1  . ASP B 1 288 ? 114.139 117.957 89.268  1.00 67.80  ? 288 ASP B OD1  1 
ATOM   5015 O  OD2  . ASP B 1 288 ? 114.077 119.021 87.347  1.00 67.80  ? 288 ASP B OD2  1 
ATOM   5016 N  N    . VAL B 1 289 ? 111.376 120.570 92.349  1.00 63.22  ? 289 VAL B N    1 
ATOM   5017 C  CA   . VAL B 1 289 ? 110.922 121.632 93.239  1.00 63.22  ? 289 VAL B CA   1 
ATOM   5018 C  C    . VAL B 1 289 ? 112.013 122.686 93.422  1.00 63.22  ? 289 VAL B C    1 
ATOM   5019 O  O    . VAL B 1 289 ? 111.723 123.884 93.539  1.00 63.22  ? 289 VAL B O    1 
ATOM   5020 C  CB   . VAL B 1 289 ? 110.449 121.030 94.573  1.00 63.22  ? 289 VAL B CB   1 
ATOM   5021 C  CG1  . VAL B 1 289 ? 111.521 120.160 95.180  1.00 63.22  ? 289 VAL B CG1  1 
ATOM   5022 C  CG2  . VAL B 1 289 ? 110.015 122.111 95.533  1.00 63.22  ? 289 VAL B CG2  1 
ATOM   5023 N  N    . PHE B 1 290 ? 113.286 122.278 93.368  1.00 62.39  ? 290 PHE B N    1 
ATOM   5024 C  CA   . PHE B 1 290 ? 114.368 123.226 93.633  1.00 62.39  ? 290 PHE B CA   1 
ATOM   5025 C  C    . PHE B 1 290 ? 114.581 124.198 92.488  1.00 62.39  ? 290 PHE B C    1 
ATOM   5026 O  O    . PHE B 1 290 ? 114.594 125.414 92.693  1.00 62.39  ? 290 PHE B O    1 
ATOM   5027 C  CB   . PHE B 1 290 ? 115.683 122.512 93.919  1.00 62.39  ? 290 PHE B CB   1 
ATOM   5028 C  CG   . PHE B 1 290 ? 115.832 122.084 95.329  1.00 62.39  ? 290 PHE B CG   1 
ATOM   5029 C  CD1  . PHE B 1 290 ? 114.753 122.052 96.171  1.00 62.39  ? 290 PHE B CD1  1 
ATOM   5030 C  CD2  . PHE B 1 290 ? 117.088 121.853 95.849  1.00 62.39  ? 290 PHE B CD2  1 
ATOM   5031 C  CE1  . PHE B 1 290 ? 114.906 121.697 97.469  1.00 62.39  ? 290 PHE B CE1  1 
ATOM   5032 C  CE2  . PHE B 1 290 ? 117.250 121.502 97.156  1.00 62.39  ? 290 PHE B CE2  1 
ATOM   5033 C  CZ   . PHE B 1 290 ? 116.157 121.426 97.972  1.00 62.39  ? 290 PHE B CZ   1 
ATOM   5034 N  N    . GLU B 1 291 ? 114.770 123.690 91.275  1.00 75.68  ? 291 GLU B N    1 
ATOM   5035 C  CA   . GLU B 1 291 ? 115.260 124.555 90.209  1.00 75.68  ? 291 GLU B CA   1 
ATOM   5036 C  C    . GLU B 1 291 ? 114.230 125.591 89.786  1.00 75.68  ? 291 GLU B C    1 
ATOM   5037 O  O    . GLU B 1 291 ? 114.577 126.534 89.067  1.00 75.68  ? 291 GLU B O    1 
ATOM   5038 C  CB   . GLU B 1 291 ? 115.692 123.705 89.017  1.00 75.68  ? 291 GLU B CB   1 
ATOM   5039 C  CG   . GLU B 1 291 ? 117.120 123.195 89.133  1.00 75.68  ? 291 GLU B CG   1 
ATOM   5040 C  CD   . GLU B 1 291 ? 117.283 122.183 90.259  1.00 75.68  ? 291 GLU B CD   1 
ATOM   5041 O  OE1  . GLU B 1 291 ? 116.310 121.468 90.574  1.00 75.68  ? 291 GLU B OE1  1 
ATOM   5042 O  OE2  . GLU B 1 291 ? 118.385 122.109 90.842  1.00 75.68  ? 291 GLU B OE2  1 
ATOM   5043 N  N    . LYS B 1 292 ? 112.981 125.445 90.225  1.00 73.59  ? 292 LYS B N    1 
ATOM   5044 C  CA   . LYS B 1 292 ? 111.957 126.451 90.004  1.00 73.59  ? 292 LYS B CA   1 
ATOM   5045 C  C    . LYS B 1 292 ? 111.547 127.202 91.261  1.00 73.59  ? 292 LYS B C    1 
ATOM   5046 O  O    . LYS B 1 292 ? 111.128 128.355 91.155  1.00 73.59  ? 292 LYS B O    1 
ATOM   5047 C  CB   . LYS B 1 292 ? 110.715 125.821 89.361  1.00 73.59  ? 292 LYS B CB   1 
ATOM   5048 C  CG   . LYS B 1 292 ? 111.049 124.895 88.201  1.00 73.59  ? 292 LYS B CG   1 
ATOM   5049 C  CD   . LYS B 1 292 ? 109.800 124.336 87.550  1.00 73.59  ? 292 LYS B CD   1 
ATOM   5050 C  CE   . LYS B 1 292 ? 109.224 123.193 88.352  1.00 73.59  ? 292 LYS B CE   1 
ATOM   5051 N  NZ   . LYS B 1 292 ? 109.860 121.911 87.949  1.00 73.59  ? 292 LYS B NZ   1 
ATOM   5052 N  N    . HIS B 1 293 ? 111.679 126.600 92.452  1.00 65.80  ? 293 HIS B N    1 
ATOM   5053 C  CA   . HIS B 1 293 ? 111.318 127.347 93.648  1.00 65.80  ? 293 HIS B CA   1 
ATOM   5054 C  C    . HIS B 1 293 ? 112.019 126.801 94.888  1.00 65.80  ? 293 HIS B C    1 
ATOM   5055 O  O    . HIS B 1 293 ? 111.428 126.010 95.629  1.00 65.80  ? 293 HIS B O    1 
ATOM   5056 C  CB   . HIS B 1 293 ? 109.804 127.320 93.857  1.00 65.80  ? 293 HIS B CB   1 
ATOM   5057 C  CG   . HIS B 1 293 ? 109.268 128.567 94.482  1.00 65.80  ? 293 HIS B CG   1 
ATOM   5058 N  ND1  . HIS B 1 293 ? 107.925 128.780 94.692  1.00 65.80  ? 293 HIS B ND1  1 
ATOM   5059 C  CD2  . HIS B 1 293 ? 109.897 129.682 94.927  1.00 65.80  ? 293 HIS B CD2  1 
ATOM   5060 C  CE1  . HIS B 1 293 ? 107.747 129.965 95.246  1.00 65.80  ? 293 HIS B CE1  1 
ATOM   5061 N  NE2  . HIS B 1 293 ? 108.928 130.533 95.400  1.00 65.80  ? 293 HIS B NE2  1 
ATOM   5062 N  N    . PRO B 1 294 ? 113.282 127.186 95.139  1.00 63.43  ? 294 PRO B N    1 
ATOM   5063 C  CA   . PRO B 1 294 ? 113.921 126.857 96.417  1.00 63.43  ? 294 PRO B CA   1 
ATOM   5064 C  C    . PRO B 1 294 ? 113.591 127.930 97.428  1.00 63.43  ? 294 PRO B C    1 
ATOM   5065 O  O    . PRO B 1 294 ? 112.746 128.786 97.154  1.00 63.43  ? 294 PRO B O    1 
ATOM   5066 C  CB   . PRO B 1 294 ? 115.408 126.855 96.075  1.00 63.43  ? 294 PRO B CB   1 
ATOM   5067 C  CG   . PRO B 1 294 ? 115.518 127.860 94.973  1.00 63.43  ? 294 PRO B CG   1 
ATOM   5068 C  CD   . PRO B 1 294 ? 114.159 128.023 94.312  1.00 63.43  ? 294 PRO B CD   1 
ATOM   5069 N  N    . CYS B 1 295 ? 114.214 127.884 98.602  1.00 57.83  ? 295 CYS B N    1 
ATOM   5070 C  CA   . CYS B 1 295 ? 114.075 128.851 99.689  1.00 57.83  ? 295 CYS B CA   1 
ATOM   5071 C  C    . CYS B 1 295 ? 112.692 128.849 100.315 1.00 57.83  ? 295 CYS B C    1 
ATOM   5072 O  O    . CYS B 1 295 ? 112.493 129.526 101.322 1.00 57.83  ? 295 CYS B O    1 
ATOM   5073 C  CB   . CYS B 1 295 ? 114.415 130.287 99.264  1.00 57.83  ? 295 CYS B CB   1 
ATOM   5074 S  SG   . CYS B 1 295 ? 116.103 130.507 98.692  1.00 57.83  ? 295 CYS B SG   1 
ATOM   5075 N  N    . LEU B 1 296 ? 111.729 128.126 99.756  1.00 50.69  ? 296 LEU B N    1 
ATOM   5076 C  CA   . LEU B 1 296 ? 110.539 127.723 100.484 1.00 50.69  ? 296 LEU B CA   1 
ATOM   5077 C  C    . LEU B 1 296 ? 110.715 126.344 101.082 1.00 50.69  ? 296 LEU B C    1 
ATOM   5078 O  O    . LEU B 1 296 ? 110.230 126.075 102.181 1.00 50.69  ? 296 LEU B O    1 
ATOM   5079 C  CB   . LEU B 1 296 ? 109.310 127.733 99.572  1.00 50.69  ? 296 LEU B CB   1 
ATOM   5080 C  CG   . LEU B 1 296 ? 108.480 129.014 99.488  1.00 50.69  ? 296 LEU B CG   1 
ATOM   5081 C  CD1  . LEU B 1 296 ? 107.873 129.309 100.837 1.00 50.69  ? 296 LEU B CD1  1 
ATOM   5082 C  CD2  . LEU B 1 296 ? 109.279 130.214 98.999  1.00 50.69  ? 296 LEU B CD2  1 
ATOM   5083 N  N    . TYR B 1 297 ? 111.433 125.480 100.375 1.00 44.16  ? 297 TYR B N    1 
ATOM   5084 C  CA   . TYR B 1 297 ? 111.757 124.162 100.900 1.00 44.16  ? 297 TYR B CA   1 
ATOM   5085 C  C    . TYR B 1 297 ? 112.675 124.272 102.111 1.00 44.16  ? 297 TYR B C    1 
ATOM   5086 O  O    . TYR B 1 297 ? 112.434 123.644 103.156 1.00 44.16  ? 297 TYR B O    1 
ATOM   5087 C  CB   . TYR B 1 297 ? 112.408 123.353 99.788  1.00 44.16  ? 297 TYR B CB   1 
ATOM   5088 C  CG   . TYR B 1 297 ? 112.751 121.941 100.127 1.00 44.16  ? 297 TYR B CG   1 
ATOM   5089 C  CD1  . TYR B 1 297 ? 113.980 121.618 100.652 1.00 44.16  ? 297 TYR B CD1  1 
ATOM   5090 C  CD2  . TYR B 1 297 ? 111.867 120.924 99.860  1.00 44.16  ? 297 TYR B CD2  1 
ATOM   5091 C  CE1  . TYR B 1 297 ? 114.301 120.335 100.934 1.00 44.16  ? 297 TYR B CE1  1 
ATOM   5092 C  CE2  . TYR B 1 297 ? 112.180 119.634 100.142 1.00 44.16  ? 297 TYR B CE2  1 
ATOM   5093 C  CZ   . TYR B 1 297 ? 113.402 119.347 100.670 1.00 44.16  ? 297 TYR B CZ   1 
ATOM   5094 O  OH   . TYR B 1 297 ? 113.733 118.054 100.968 1.00 44.16  ? 297 TYR B OH   1 
ATOM   5095 N  N    . ILE B 1 298 ? 113.742 125.065 101.988 1.00 47.15  ? 298 ILE B N    1 
ATOM   5096 C  CA   . ILE B 1 298 ? 114.653 125.233 103.112 1.00 47.15  ? 298 ILE B CA   1 
ATOM   5097 C  C    . ILE B 1 298 ? 113.967 125.969 104.249 1.00 47.15  ? 298 ILE B C    1 
ATOM   5098 O  O    . ILE B 1 298 ? 114.219 125.666 105.409 1.00 47.15  ? 298 ILE B O    1 
ATOM   5099 C  CB   . ILE B 1 298 ? 115.953 125.928 102.683 1.00 47.15  ? 298 ILE B CB   1 
ATOM   5100 C  CG1  . ILE B 1 298 ? 116.661 125.084 101.636 1.00 47.15  ? 298 ILE B CG1  1 
ATOM   5101 C  CG2  . ILE B 1 298 ? 116.886 126.085 103.848 1.00 47.15  ? 298 ILE B CG2  1 
ATOM   5102 C  CD1  . ILE B 1 298 ? 118.009 125.622 101.241 1.00 47.15  ? 298 ILE B CD1  1 
ATOM   5103 N  N    . LEU B 1 299 ? 113.065 126.908 103.962 1.00 43.35  ? 299 LEU B N    1 
ATOM   5104 C  CA   . LEU B 1 299 ? 112.324 127.531 105.055 1.00 43.35  ? 299 LEU B CA   1 
ATOM   5105 C  C    . LEU B 1 299 ? 111.357 126.564 105.729 1.00 43.35  ? 299 LEU B C    1 
ATOM   5106 O  O    . LEU B 1 299 ? 111.105 126.688 106.933 1.00 43.35  ? 299 LEU B O    1 
ATOM   5107 C  CB   . LEU B 1 299 ? 111.572 128.760 104.573 1.00 43.35  ? 299 LEU B CB   1 
ATOM   5108 C  CG   . LEU B 1 299 ? 112.425 130.019 104.546 1.00 43.35  ? 299 LEU B CG   1 
ATOM   5109 C  CD1  . LEU B 1 299 ? 111.599 131.206 104.101 1.00 43.35  ? 299 LEU B CD1  1 
ATOM   5110 C  CD2  . LEU B 1 299 ? 113.002 130.255 105.916 1.00 43.35  ? 299 LEU B CD2  1 
ATOM   5111 N  N    . MET B 1 300 ? 110.801 125.603 104.993 1.00 47.17  ? 300 MET B N    1 
ATOM   5112 C  CA   . MET B 1 300 ? 109.886 124.658 105.624 1.00 47.17  ? 300 MET B CA   1 
ATOM   5113 C  C    . MET B 1 300 ? 110.639 123.717 106.551 1.00 47.17  ? 300 MET B C    1 
ATOM   5114 O  O    . MET B 1 300 ? 110.266 123.544 107.724 1.00 47.17  ? 300 MET B O    1 
ATOM   5115 C  CB   . MET B 1 300 ? 109.108 123.890 104.562 1.00 47.17  ? 300 MET B CB   1 
ATOM   5116 C  CG   . MET B 1 300 ? 108.094 122.937 105.118 1.00 47.17  ? 300 MET B CG   1 
ATOM   5117 S  SD   . MET B 1 300 ? 108.057 121.432 104.160 1.00 47.17  ? 300 MET B SD   1 
ATOM   5118 C  CE   . MET B 1 300 ? 109.609 120.746 104.664 1.00 47.17  ? 300 MET B CE   1 
ATOM   5119 N  N    . PHE B 1 301 ? 111.741 123.144 106.067 1.00 45.30  ? 301 PHE B N    1 
ATOM   5120 C  CA   . PHE B 1 301 ? 112.601 122.459 107.024 1.00 45.30  ? 301 PHE B CA   1 
ATOM   5121 C  C    . PHE B 1 301 ? 113.216 123.406 108.038 1.00 45.30  ? 301 PHE B C    1 
ATOM   5122 O  O    . PHE B 1 301 ? 113.635 122.953 109.099 1.00 45.30  ? 301 PHE B O    1 
ATOM   5123 C  CB   . PHE B 1 301 ? 113.689 121.640 106.347 1.00 45.30  ? 301 PHE B CB   1 
ATOM   5124 C  CG   . PHE B 1 301 ? 113.186 120.393 105.709 1.00 45.30  ? 301 PHE B CG   1 
ATOM   5125 C  CD1  . PHE B 1 301 ? 112.930 119.287 106.488 1.00 45.30  ? 301 PHE B CD1  1 
ATOM   5126 C  CD2  . PHE B 1 301 ? 113.036 120.288 104.350 1.00 45.30  ? 301 PHE B CD2  1 
ATOM   5127 C  CE1  . PHE B 1 301 ? 112.478 118.122 105.930 1.00 45.30  ? 301 PHE B CE1  1 
ATOM   5128 C  CE2  . PHE B 1 301 ? 112.585 119.113 103.792 1.00 45.30  ? 301 PHE B CE2  1 
ATOM   5129 C  CZ   . PHE B 1 301 ? 112.310 118.034 104.581 1.00 45.30  ? 301 PHE B CZ   1 
ATOM   5130 N  N    . GLY B 1 302 ? 113.239 124.707 107.772 1.00 47.07  ? 302 GLY B N    1 
ATOM   5131 C  CA   . GLY B 1 302 ? 113.696 125.641 108.780 1.00 47.07  ? 302 GLY B CA   1 
ATOM   5132 C  C    . GLY B 1 302 ? 112.756 125.728 109.960 1.00 47.07  ? 302 GLY B C    1 
ATOM   5133 O  O    . GLY B 1 302 ? 113.191 125.694 111.108 1.00 47.07  ? 302 GLY B O    1 
ATOM   5134 N  N    . CYS B 1 303 ? 111.456 125.818 109.693 1.00 45.65  ? 303 CYS B N    1 
ATOM   5135 C  CA   . CYS B 1 303 ? 110.491 125.826 110.789 1.00 45.65  ? 303 CYS B CA   1 
ATOM   5136 C  C    . CYS B 1 303 ? 110.464 124.485 111.512 1.00 45.65  ? 303 CYS B C    1 
ATOM   5137 O  O    . CYS B 1 303 ? 110.371 124.437 112.749 1.00 45.65  ? 303 CYS B O    1 
ATOM   5138 C  CB   . CYS B 1 303 ? 109.106 126.201 110.277 1.00 45.65  ? 303 CYS B CB   1 
ATOM   5139 S  SG   . CYS B 1 303 ? 108.943 127.946 109.848 1.00 45.65  ? 303 CYS B SG   1 
ATOM   5140 N  N    . VAL B 1 304 ? 110.568 123.380 110.767 1.00 44.69  ? 304 VAL B N    1 
ATOM   5141 C  CA   . VAL B 1 304 ? 110.575 122.068 111.412 1.00 44.69  ? 304 VAL B CA   1 
ATOM   5142 C  C    . VAL B 1 304 ? 111.805 121.904 112.298 1.00 44.69  ? 304 VAL B C    1 
ATOM   5143 O  O    . VAL B 1 304 ? 111.708 121.493 113.464 1.00 44.69  ? 304 VAL B O    1 
ATOM   5144 C  CB   . VAL B 1 304 ? 110.489 120.960 110.354 1.00 44.69  ? 304 VAL B CB   1 
ATOM   5145 C  CG1  . VAL B 1 304 ? 110.812 119.629 110.964 1.00 44.69  ? 304 VAL B CG1  1 
ATOM   5146 C  CG2  . VAL B 1 304 ? 109.116 120.950 109.783 1.00 44.69  ? 304 VAL B CG2  1 
ATOM   5147 N  N    . PHE B 1 305 ? 112.977 122.243 111.767 1.00 47.14  ? 305 PHE B N    1 
ATOM   5148 C  CA   . PHE B 1 305 ? 114.199 122.171 112.551 1.00 47.14  ? 305 PHE B CA   1 
ATOM   5149 C  C    . PHE B 1 305 ? 114.180 123.165 113.695 1.00 47.14  ? 305 PHE B C    1 
ATOM   5150 O  O    . PHE B 1 305 ? 114.779 122.908 114.742 1.00 47.14  ? 305 PHE B O    1 
ATOM   5151 C  CB   . PHE B 1 305 ? 115.397 122.402 111.639 1.00 47.14  ? 305 PHE B CB   1 
ATOM   5152 C  CG   . PHE B 1 305 ? 116.619 122.858 112.350 1.00 47.14  ? 305 PHE B CG   1 
ATOM   5153 C  CD1  . PHE B 1 305 ? 117.396 121.962 113.037 1.00 47.14  ? 305 PHE B CD1  1 
ATOM   5154 C  CD2  . PHE B 1 305 ? 116.998 124.182 112.321 1.00 47.14  ? 305 PHE B CD2  1 
ATOM   5155 C  CE1  . PHE B 1 305 ? 118.518 122.377 113.687 1.00 47.14  ? 305 PHE B CE1  1 
ATOM   5156 C  CE2  . PHE B 1 305 ? 118.119 124.599 112.971 1.00 47.14  ? 305 PHE B CE2  1 
ATOM   5157 C  CZ   . PHE B 1 305 ? 118.881 123.698 113.655 1.00 47.14  ? 305 PHE B CZ   1 
ATOM   5158 N  N    . ALA B 1 306 ? 113.487 124.291 113.531 1.00 50.56  ? 306 ALA B N    1 
ATOM   5159 C  CA   . ALA B 1 306 ? 113.363 125.244 114.620 1.00 50.56  ? 306 ALA B CA   1 
ATOM   5160 C  C    . ALA B 1 306 ? 112.603 124.641 115.789 1.00 50.56  ? 306 ALA B C    1 
ATOM   5161 O  O    . ALA B 1 306 ? 113.038 124.756 116.938 1.00 50.56  ? 306 ALA B O    1 
ATOM   5162 C  CB   . ALA B 1 306 ? 112.676 126.515 114.132 1.00 50.56  ? 306 ALA B CB   1 
ATOM   5163 N  N    . LYS B 1 307 ? 111.478 123.974 115.518 1.00 53.58  ? 307 LYS B N    1 
ATOM   5164 C  CA   . LYS B 1 307 ? 110.767 123.341 116.626 1.00 53.58  ? 307 LYS B CA   1 
ATOM   5165 C  C    . LYS B 1 307 ? 111.586 122.212 117.242 1.00 53.58  ? 307 LYS B C    1 
ATOM   5166 O  O    . LYS B 1 307 ? 111.617 122.069 118.469 1.00 53.58  ? 307 LYS B O    1 
ATOM   5167 C  CB   . LYS B 1 307 ? 109.396 122.820 116.208 1.00 53.58  ? 307 LYS B CB   1 
ATOM   5168 C  CG   . LYS B 1 307 ? 108.717 122.113 117.375 1.00 53.58  ? 307 LYS B CG   1 
ATOM   5169 C  CD   . LYS B 1 307 ? 107.300 121.710 117.114 1.00 53.58  ? 307 LYS B CD   1 
ATOM   5170 C  CE   . LYS B 1 307 ? 106.774 120.774 118.187 1.00 53.58  ? 307 LYS B CE   1 
ATOM   5171 N  NZ   . LYS B 1 307 ? 106.689 121.420 119.516 1.00 53.58  ? 307 LYS B NZ   1 
ATOM   5172 N  N    . VAL B 1 308 ? 112.264 121.411 116.420 1.00 50.03  ? 308 VAL B N    1 
ATOM   5173 C  CA   . VAL B 1 308 ? 113.037 120.302 116.978 1.00 50.03  ? 308 VAL B CA   1 
ATOM   5174 C  C    . VAL B 1 308 ? 114.171 120.818 117.862 1.00 50.03  ? 308 VAL B C    1 
ATOM   5175 O  O    . VAL B 1 308 ? 114.399 120.308 118.970 1.00 50.03  ? 308 VAL B O    1 
ATOM   5176 C  CB   . VAL B 1 308 ? 113.554 119.397 115.849 1.00 50.03  ? 308 VAL B CB   1 
ATOM   5177 C  CG1  . VAL B 1 308 ? 114.622 118.493 116.370 1.00 50.03  ? 308 VAL B CG1  1 
ATOM   5178 C  CG2  . VAL B 1 308 ? 112.419 118.582 115.290 1.00 50.03  ? 308 VAL B CG2  1 
ATOM   5179 N  N    . SER B 1 309 ? 114.873 121.858 117.413 1.00 53.90  ? 309 SER B N    1 
ATOM   5180 C  CA   . SER B 1 309 ? 115.938 122.419 118.231 1.00 53.90  ? 309 SER B CA   1 
ATOM   5181 C  C    . SER B 1 309 ? 115.394 123.101 119.477 1.00 53.90  ? 309 SER B C    1 
ATOM   5182 O  O    . SER B 1 309 ? 116.033 123.042 120.528 1.00 53.90  ? 309 SER B O    1 
ATOM   5183 C  CB   . SER B 1 309 ? 116.769 123.406 117.426 1.00 53.90  ? 309 SER B CB   1 
ATOM   5184 O  OG   . SER B 1 309 ? 116.028 124.585 117.196 1.00 53.90  ? 309 SER B OG   1 
ATOM   5185 N  N    . GLN B 1 310 ? 114.226 123.743 119.394 1.00 58.98  ? 310 GLN B N    1 
ATOM   5186 C  CA   . GLN B 1 310 ? 113.614 124.309 120.594 1.00 58.98  ? 310 GLN B CA   1 
ATOM   5187 C  C    . GLN B 1 310 ? 113.285 123.216 121.604 1.00 58.98  ? 310 GLN B C    1 
ATOM   5188 O  O    . GLN B 1 310 ? 113.457 123.403 122.816 1.00 58.98  ? 310 GLN B O    1 
ATOM   5189 C  CB   . GLN B 1 310 ? 112.354 125.086 120.229 1.00 58.98  ? 310 GLN B CB   1 
ATOM   5190 C  CG   . GLN B 1 310 ? 112.583 126.525 119.829 1.00 58.98  ? 310 GLN B CG   1 
ATOM   5191 C  CD   . GLN B 1 310 ? 111.329 127.168 119.273 1.00 58.98  ? 310 GLN B CD   1 
ATOM   5192 O  OE1  . GLN B 1 310 ? 110.284 126.535 119.184 1.00 58.98  ? 310 GLN B OE1  1 
ATOM   5193 N  NE2  . GLN B 1 310 ? 111.427 128.436 118.898 1.00 58.98  ? 310 GLN B NE2  1 
ATOM   5194 N  N    . LYS B 1 311 ? 112.807 122.072 121.118 1.00 58.28  ? 311 LYS B N    1 
ATOM   5195 C  CA   . LYS B 1 311 ? 112.531 120.951 122.007 1.00 58.28  ? 311 LYS B CA   1 
ATOM   5196 C  C    . LYS B 1 311 ? 113.802 120.461 122.675 1.00 58.28  ? 311 LYS B C    1 
ATOM   5197 O  O    . LYS B 1 311 ? 113.796 120.138 123.867 1.00 58.28  ? 311 LYS B O    1 
ATOM   5198 C  CB   . LYS B 1 311 ? 111.858 119.824 121.238 1.00 58.28  ? 311 LYS B CB   1 
ATOM   5199 C  CG   . LYS B 1 311 ? 110.376 119.714 121.497 1.00 58.28  ? 311 LYS B CG   1 
ATOM   5200 C  CD   . LYS B 1 311 ? 109.799 118.545 120.752 1.00 58.28  ? 311 LYS B CD   1 
ATOM   5201 C  CE   . LYS B 1 311 ? 110.428 117.262 121.217 1.00 58.28  ? 311 LYS B CE   1 
ATOM   5202 N  NZ   . LYS B 1 311 ? 110.060 116.142 120.327 1.00 58.28  ? 311 LYS B NZ   1 
ATOM   5203 N  N    . LEU B 1 312 ? 114.908 120.404 121.936 1.00 55.32  ? 312 LEU B N    1 
ATOM   5204 C  CA   . LEU B 1 312 ? 116.151 119.993 122.585 1.00 55.32  ? 312 LEU B CA   1 
ATOM   5205 C  C    . LEU B 1 312 ? 116.647 121.051 123.565 1.00 55.32  ? 312 LEU B C    1 
ATOM   5206 O  O    . LEU B 1 312 ? 117.281 120.709 124.570 1.00 55.32  ? 312 LEU B O    1 
ATOM   5207 C  CB   . LEU B 1 312 ? 117.226 119.671 121.554 1.00 55.32  ? 312 LEU B CB   1 
ATOM   5208 C  CG   . LEU B 1 312 ? 118.444 118.933 122.110 1.00 55.32  ? 312 LEU B CG   1 
ATOM   5209 C  CD1  . LEU B 1 312 ? 118.922 117.935 121.107 1.00 55.32  ? 312 LEU B CD1  1 
ATOM   5210 C  CD2  . LEU B 1 312 ? 119.578 119.860 122.435 1.00 55.32  ? 312 LEU B CD2  1 
ATOM   5211 N  N    . VAL B 1 313 ? 116.372 122.329 123.297 1.00 63.20  ? 313 VAL B N    1 
ATOM   5212 C  CA   . VAL B 1 313 ? 116.706 123.376 124.263 1.00 63.20  ? 313 VAL B CA   1 
ATOM   5213 C  C    . VAL B 1 313 ? 115.967 123.140 125.571 1.00 63.20  ? 313 VAL B C    1 
ATOM   5214 O  O    . VAL B 1 313 ? 116.569 123.127 126.656 1.00 63.20  ? 313 VAL B O    1 
ATOM   5215 C  CB   . VAL B 1 313 ? 116.401 124.769 123.691 1.00 63.20  ? 313 VAL B CB   1 
ATOM   5216 C  CG1  . VAL B 1 313 ? 116.594 125.807 124.760 1.00 63.20  ? 313 VAL B CG1  1 
ATOM   5217 C  CG2  . VAL B 1 313 ? 117.339 125.076 122.557 1.00 63.20  ? 313 VAL B CG2  1 
ATOM   5218 N  N    . VAL B 1 314 ? 114.656 122.912 125.478 1.00 66.48  ? 314 VAL B N    1 
ATOM   5219 C  CA   . VAL B 1 314 ? 113.853 122.611 126.658 1.00 66.48  ? 314 VAL B CA   1 
ATOM   5220 C  C    . VAL B 1 314 ? 114.372 121.357 127.344 1.00 66.48  ? 314 VAL B C    1 
ATOM   5221 O  O    . VAL B 1 314 ? 114.424 121.280 128.575 1.00 66.48  ? 314 VAL B O    1 
ATOM   5222 C  CB   . VAL B 1 314 ? 112.374 122.479 126.269 1.00 66.48  ? 314 VAL B CB   1 
ATOM   5223 C  CG1  . VAL B 1 314 ? 111.559 121.984 127.429 1.00 66.48  ? 314 VAL B CG1  1 
ATOM   5224 C  CG2  . VAL B 1 314 ? 111.854 123.808 125.806 1.00 66.48  ? 314 VAL B CG2  1 
ATOM   5225 N  N    . ALA B 1 315 ? 114.813 120.377 126.561 1.00 70.47  ? 315 ALA B N    1 
ATOM   5226 C  CA   . ALA B 1 315 ? 115.313 119.144 127.147 1.00 70.47  ? 315 ALA B CA   1 
ATOM   5227 C  C    . ALA B 1 315 ? 116.624 119.340 127.897 1.00 70.47  ? 315 ALA B C    1 
ATOM   5228 O  O    . ALA B 1 315 ? 116.852 118.663 128.900 1.00 70.47  ? 315 ALA B O    1 
ATOM   5229 C  CB   . ALA B 1 315 ? 115.484 118.081 126.068 1.00 70.47  ? 315 ALA B CB   1 
ATOM   5230 N  N    . HIS B 1 316 ? 117.510 120.232 127.447 1.00 72.30  ? 316 HIS B N    1 
ATOM   5231 C  CA   . HIS B 1 316 ? 118.756 120.289 128.203 1.00 72.30  ? 316 HIS B CA   1 
ATOM   5232 C  C    . HIS B 1 316 ? 118.692 121.286 129.344 1.00 72.30  ? 316 HIS B C    1 
ATOM   5233 O  O    . HIS B 1 316 ? 119.424 121.128 130.325 1.00 72.30  ? 316 HIS B O    1 
ATOM   5234 C  CB   . HIS B 1 316 ? 119.986 120.640 127.364 1.00 72.30  ? 316 HIS B CB   1 
ATOM   5235 C  CG   . HIS B 1 316 ? 119.960 122.001 126.750 1.00 72.30  ? 316 HIS B CG   1 
ATOM   5236 N  ND1  . HIS B 1 316 ? 120.401 123.119 127.426 1.00 72.30  ? 316 HIS B ND1  1 
ATOM   5237 C  CD2  . HIS B 1 316 ? 119.660 122.414 125.499 1.00 72.30  ? 316 HIS B CD2  1 
ATOM   5238 C  CE1  . HIS B 1 316 ? 120.313 124.173 126.636 1.00 72.30  ? 316 HIS B CE1  1 
ATOM   5239 N  NE2  . HIS B 1 316 ? 119.862 123.772 125.461 1.00 72.30  ? 316 HIS B NE2  1 
ATOM   5240 N  N    . MET B 1 317 ? 117.864 122.327 129.255 1.00 83.95  ? 317 MET B N    1 
ATOM   5241 C  CA   . MET B 1 317 ? 117.772 123.142 130.457 1.00 83.95  ? 317 MET B CA   1 
ATOM   5242 C  C    . MET B 1 317 ? 116.653 122.702 131.385 1.00 83.95  ? 317 MET B C    1 
ATOM   5243 O  O    . MET B 1 317 ? 116.508 123.275 132.467 1.00 83.95  ? 317 MET B O    1 
ATOM   5244 C  CB   . MET B 1 317 ? 117.610 124.621 130.124 1.00 83.95  ? 317 MET B CB   1 
ATOM   5245 C  CG   . MET B 1 317 ? 116.511 124.974 129.179 1.00 83.95  ? 317 MET B CG   1 
ATOM   5246 S  SD   . MET B 1 317 ? 116.054 126.676 129.495 1.00 83.95  ? 317 MET B SD   1 
ATOM   5247 C  CE   . MET B 1 317 ? 117.261 127.480 128.458 1.00 83.95  ? 317 MET B CE   1 
ATOM   5248 N  N    . THR B 1 318 ? 115.862 121.704 130.997 1.00 84.03  ? 318 THR B N    1 
ATOM   5249 C  CA   . THR B 1 318 ? 114.919 121.064 131.901 1.00 84.03  ? 318 THR B CA   1 
ATOM   5250 C  C    . THR B 1 318 ? 115.070 119.567 131.709 1.00 84.03  ? 318 THR B C    1 
ATOM   5251 O  O    . THR B 1 318 ? 114.696 119.044 130.654 1.00 84.03  ? 318 THR B O    1 
ATOM   5252 C  CB   . THR B 1 318 ? 113.481 121.506 131.625 1.00 84.03  ? 318 THR B CB   1 
ATOM   5253 O  OG1  . THR B 1 318 ? 113.330 122.883 131.978 1.00 84.03  ? 318 THR B OG1  1 
ATOM   5254 C  CG2  . THR B 1 318 ? 112.516 120.683 132.432 1.00 84.03  ? 318 THR B CG2  1 
ATOM   5255 N  N    . LYS B 1 319 ? 115.604 118.884 132.718 1.00 86.78  ? 319 LYS B N    1 
ATOM   5256 C  CA   . LYS B 1 319 ? 116.081 117.518 132.553 1.00 86.78  ? 319 LYS B CA   1 
ATOM   5257 C  C    . LYS B 1 319 ? 114.948 116.578 132.178 1.00 86.78  ? 319 LYS B C    1 
ATOM   5258 O  O    . LYS B 1 319 ? 114.102 116.244 133.013 1.00 86.78  ? 319 LYS B O    1 
ATOM   5259 C  CB   . LYS B 1 319 ? 116.760 117.035 133.834 1.00 86.78  ? 319 LYS B CB   1 
ATOM   5260 C  CG   . LYS B 1 319 ? 118.225 117.404 133.944 1.00 86.78  ? 319 LYS B CG   1 
ATOM   5261 C  CD   . LYS B 1 319 ? 118.404 118.818 134.468 1.00 86.78  ? 319 LYS B CD   1 
ATOM   5262 C  CE   . LYS B 1 319 ? 119.710 118.961 135.226 1.00 86.78  ? 319 LYS B CE   1 
ATOM   5263 N  NZ   . LYS B 1 319 ? 119.767 120.230 136.000 1.00 86.78  ? 319 LYS B NZ   1 
ATOM   5264 N  N    . SER B 1 320 ? 114.921 116.155 130.918 1.00 76.25  ? 320 SER B N    1 
ATOM   5265 C  CA   . SER B 1 320 ? 113.833 115.339 130.405 1.00 76.25  ? 320 SER B CA   1 
ATOM   5266 C  C    . SER B 1 320 ? 114.339 114.558 129.206 1.00 76.25  ? 320 SER B C    1 
ATOM   5267 O  O    . SER B 1 320 ? 115.380 114.878 128.629 1.00 76.25  ? 320 SER B O    1 
ATOM   5268 C  CB   . SER B 1 320 ? 112.625 116.193 130.014 1.00 76.25  ? 320 SER B CB   1 
ATOM   5269 O  OG   . SER B 1 320 ? 112.094 116.882 131.132 1.00 76.25  ? 320 SER B OG   1 
ATOM   5270 N  N    . GLU B 1 321 ? 113.588 113.528 128.839 1.00 70.35  ? 321 GLU B N    1 
ATOM   5271 C  CA   . GLU B 1 321 ? 113.930 112.705 127.690 1.00 70.35  ? 321 GLU B CA   1 
ATOM   5272 C  C    . GLU B 1 321 ? 113.402 113.358 126.421 1.00 70.35  ? 321 GLU B C    1 
ATOM   5273 O  O    . GLU B 1 321 ? 112.371 114.035 126.440 1.00 70.35  ? 321 GLU B O    1 
ATOM   5274 C  CB   . GLU B 1 321 ? 113.349 111.297 127.845 1.00 70.35  ? 321 GLU B CB   1 
ATOM   5275 C  CG   . GLU B 1 321 ? 113.947 110.255 126.906 1.00 70.35  ? 321 GLU B CG   1 
ATOM   5276 C  CD   . GLU B 1 321 ? 113.307 108.888 127.053 1.00 70.35  ? 321 GLU B CD   1 
ATOM   5277 O  OE1  . GLU B 1 321 ? 112.726 108.617 128.126 1.00 70.35  ? 321 GLU B OE1  1 
ATOM   5278 O  OE2  . GLU B 1 321 ? 113.388 108.084 126.100 1.00 70.35  ? 321 GLU B OE2  1 
ATOM   5279 N  N    . LEU B 1 322 ? 114.125 113.164 125.321 1.00 66.90  ? 322 LEU B N    1 
ATOM   5280 C  CA   . LEU B 1 322 ? 113.649 113.638 124.031 1.00 66.90  ? 322 LEU B CA   1 
ATOM   5281 C  C    . LEU B 1 322 ? 112.526 112.749 123.521 1.00 66.90  ? 322 LEU B C    1 
ATOM   5282 O  O    . LEU B 1 322 ? 112.445 111.561 123.842 1.00 66.90  ? 322 LEU B O    1 
ATOM   5283 C  CB   . LEU B 1 322 ? 114.776 113.666 123.003 1.00 66.90  ? 322 LEU B CB   1 
ATOM   5284 C  CG   . LEU B 1 322 ? 115.705 114.875 122.938 1.00 66.90  ? 322 LEU B CG   1 
ATOM   5285 C  CD1  . LEU B 1 322 ? 114.923 116.125 122.571 1.00 66.90  ? 322 LEU B CD1  1 
ATOM   5286 C  CD2  . LEU B 1 322 ? 116.483 115.072 124.212 1.00 66.90  ? 322 LEU B CD2  1 
ATOM   5287 N  N    . TYR B 1 323 ? 111.649 113.337 122.718 1.00 64.09  ? 323 TYR B N    1 
ATOM   5288 C  CA   . TYR B 1 323 ? 110.524 112.624 122.136 1.00 64.09  ? 323 TYR B CA   1 
ATOM   5289 C  C    . TYR B 1 323 ? 110.557 112.801 120.626 1.00 64.09  ? 323 TYR B C    1 
ATOM   5290 O  O    . TYR B 1 323 ? 110.704 113.921 120.132 1.00 64.09  ? 323 TYR B O    1 
ATOM   5291 C  CB   . TYR B 1 323 ? 109.196 113.126 122.707 1.00 64.09  ? 323 TYR B CB   1 
ATOM   5292 C  CG   . TYR B 1 323 ? 108.877 112.611 124.098 1.00 64.09  ? 323 TYR B CG   1 
ATOM   5293 C  CD1  . TYR B 1 323 ? 109.649 112.976 125.191 1.00 64.09  ? 323 TYR B CD1  1 
ATOM   5294 C  CD2  . TYR B 1 323 ? 107.790 111.778 124.316 1.00 64.09  ? 323 TYR B CD2  1 
ATOM   5295 C  CE1  . TYR B 1 323 ? 109.358 112.511 126.458 1.00 64.09  ? 323 TYR B CE1  1 
ATOM   5296 C  CE2  . TYR B 1 323 ? 107.494 111.307 125.583 1.00 64.09  ? 323 TYR B CE2  1 
ATOM   5297 C  CZ   . TYR B 1 323 ? 108.282 111.680 126.647 1.00 64.09  ? 323 TYR B CZ   1 
ATOM   5298 O  OH   . TYR B 1 323 ? 107.994 111.220 127.909 1.00 64.09  ? 323 TYR B OH   1 
ATOM   5299 N  N    . LEU B 1 324 ? 110.441 111.692 119.895 1.00 63.48  ? 324 LEU B N    1 
ATOM   5300 C  CA   . LEU B 1 324 ? 110.350 111.769 118.442 1.00 63.48  ? 324 LEU B CA   1 
ATOM   5301 C  C    . LEU B 1 324 ? 108.981 112.232 117.972 1.00 63.48  ? 324 LEU B C    1 
ATOM   5302 O  O    . LEU B 1 324 ? 108.885 112.888 116.929 1.00 63.48  ? 324 LEU B O    1 
ATOM   5303 C  CB   . LEU B 1 324 ? 110.673 110.414 117.817 1.00 63.48  ? 324 LEU B CB   1 
ATOM   5304 C  CG   . LEU B 1 324 ? 112.108 110.091 117.398 1.00 63.48  ? 324 LEU B CG   1 
ATOM   5305 C  CD1  . LEU B 1 324 ? 112.497 110.955 116.222 1.00 63.48  ? 324 LEU B CD1  1 
ATOM   5306 C  CD2  . LEU B 1 324 ? 113.085 110.281 118.545 1.00 63.48  ? 324 LEU B CD2  1 
ATOM   5307 N  N    . GLN B 1 325 ? 107.922 111.901 118.704 1.00 65.65  ? 325 GLN B N    1 
ATOM   5308 C  CA   . GLN B 1 325 ? 106.569 112.229 118.277 1.00 65.65  ? 325 GLN B CA   1 
ATOM   5309 C  C    . GLN B 1 325 ? 106.376 113.736 118.326 1.00 65.65  ? 325 GLN B C    1 
ATOM   5310 O  O    . GLN B 1 325 ? 106.349 114.332 119.407 1.00 65.65  ? 325 GLN B O    1 
ATOM   5311 C  CB   . GLN B 1 325 ? 105.539 111.530 119.156 1.00 65.65  ? 325 GLN B CB   1 
ATOM   5312 C  CG   . GLN B 1 325 ? 104.097 111.778 118.727 1.00 65.65  ? 325 GLN B CG   1 
ATOM   5313 C  CD   . GLN B 1 325 ? 103.378 112.794 119.598 1.00 65.65  ? 325 GLN B CD   1 
ATOM   5314 O  OE1  . GLN B 1 325 ? 103.847 113.149 120.678 1.00 65.65  ? 325 GLN B OE1  1 
ATOM   5315 N  NE2  . GLN B 1 325 ? 102.233 113.270 119.125 1.00 65.65  ? 325 GLN B NE2  1 
ATOM   5316 N  N    . ASP B 1 326 ? 106.242 114.357 117.161 1.00 65.34  ? 326 ASP B N    1 
ATOM   5317 C  CA   . ASP B 1 326 ? 105.977 115.782 117.081 1.00 65.34  ? 326 ASP B CA   1 
ATOM   5318 C  C    . ASP B 1 326 ? 104.980 116.039 115.968 1.00 65.34  ? 326 ASP B C    1 
ATOM   5319 O  O    . ASP B 1 326 ? 104.922 115.298 114.985 1.00 65.34  ? 326 ASP B O    1 
ATOM   5320 C  CB   . ASP B 1 326 ? 107.257 116.577 116.843 1.00 65.34  ? 326 ASP B CB   1 
ATOM   5321 C  CG   . ASP B 1 326 ? 107.995 116.876 118.122 1.00 65.34  ? 326 ASP B CG   1 
ATOM   5322 O  OD1  . ASP B 1 326 ? 107.341 117.299 119.097 1.00 65.34  ? 326 ASP B OD1  1 
ATOM   5323 O  OD2  . ASP B 1 326 ? 109.226 116.685 118.163 1.00 65.34  ? 326 ASP B OD2  1 
ATOM   5324 N  N    . THR B 1 327 ? 104.189 117.095 116.133 1.00 58.19  ? 327 THR B N    1 
ATOM   5325 C  CA   . THR B 1 327 ? 103.171 117.400 115.138 1.00 58.19  ? 327 THR B CA   1 
ATOM   5326 C  C    . THR B 1 327 ? 103.759 118.036 113.883 1.00 58.19  ? 327 THR B C    1 
ATOM   5327 O  O    . THR B 1 327 ? 103.191 117.876 112.798 1.00 58.19  ? 327 THR B O    1 
ATOM   5328 C  CB   . THR B 1 327 ? 102.093 118.299 115.747 1.00 58.19  ? 327 THR B CB   1 
ATOM   5329 O  OG1  . THR B 1 327 ? 101.045 118.501 114.792 1.00 58.19  ? 327 THR B OG1  1 
ATOM   5330 C  CG2  . THR B 1 327 ? 102.664 119.636 116.172 1.00 58.19  ? 327 THR B CG2  1 
ATOM   5331 N  N    . VAL B 1 328 ? 104.896 118.725 113.995 1.00 57.72  ? 328 VAL B N    1 
ATOM   5332 C  CA   . VAL B 1 328 ? 105.435 119.425 112.835 1.00 57.72  ? 328 VAL B CA   1 
ATOM   5333 C  C    . VAL B 1 328 ? 106.043 118.485 111.824 1.00 57.72  ? 328 VAL B C    1 
ATOM   5334 O  O    . VAL B 1 328 ? 106.293 118.894 110.689 1.00 57.72  ? 328 VAL B O    1 
ATOM   5335 C  CB   . VAL B 1 328 ? 106.476 120.470 113.238 1.00 57.72  ? 328 VAL B CB   1 
ATOM   5336 C  CG1  . VAL B 1 328 ? 105.800 121.581 113.981 1.00 57.72  ? 328 VAL B CG1  1 
ATOM   5337 C  CG2  . VAL B 1 328 ? 107.558 119.816 114.062 1.00 57.72  ? 328 VAL B CG2  1 
ATOM   5338 N  N    . PHE B 1 329 ? 106.279 117.229 112.186 1.00 54.91  ? 329 PHE B N    1 
ATOM   5339 C  CA   . PHE B 1 329 ? 106.672 116.287 111.152 1.00 54.91  ? 329 PHE B CA   1 
ATOM   5340 C  C    . PHE B 1 329 ? 105.526 115.975 110.206 1.00 54.91  ? 329 PHE B C    1 
ATOM   5341 O  O    . PHE B 1 329 ? 105.746 115.299 109.199 1.00 54.91  ? 329 PHE B O    1 
ATOM   5342 C  CB   . PHE B 1 329 ? 107.222 115.016 111.781 1.00 54.91  ? 329 PHE B CB   1 
ATOM   5343 C  CG   . PHE B 1 329 ? 108.662 115.121 112.151 1.00 54.91  ? 329 PHE B CG   1 
ATOM   5344 C  CD1  . PHE B 1 329 ? 109.596 115.487 111.212 1.00 54.91  ? 329 PHE B CD1  1 
ATOM   5345 C  CD2  . PHE B 1 329 ? 109.081 114.864 113.440 1.00 54.91  ? 329 PHE B CD2  1 
ATOM   5346 C  CE1  . PHE B 1 329 ? 110.919 115.593 111.547 1.00 54.91  ? 329 PHE B CE1  1 
ATOM   5347 C  CE2  . PHE B 1 329 ? 110.409 114.966 113.775 1.00 54.91  ? 329 PHE B CE2  1 
ATOM   5348 C  CZ   . PHE B 1 329 ? 111.324 115.328 112.830 1.00 54.91  ? 329 PHE B CZ   1 
ATOM   5349 N  N    . LEU B 1 330 ? 104.316 116.450 110.502 1.00 56.56  ? 330 LEU B N    1 
ATOM   5350 C  CA   . LEU B 1 330 ? 103.253 116.447 109.508 1.00 56.56  ? 330 LEU B CA   1 
ATOM   5351 C  C    . LEU B 1 330 ? 103.568 117.356 108.329 1.00 56.56  ? 330 LEU B C    1 
ATOM   5352 O  O    . LEU B 1 330 ? 102.983 117.182 107.256 1.00 56.56  ? 330 LEU B O    1 
ATOM   5353 C  CB   . LEU B 1 330 ? 101.938 116.883 110.147 1.00 56.56  ? 330 LEU B CB   1 
ATOM   5354 C  CG   . LEU B 1 330 ? 100.690 116.224 109.578 1.00 56.56  ? 330 LEU B CG   1 
ATOM   5355 C  CD1  . LEU B 1 330 ? 100.733 114.729 109.834 1.00 56.56  ? 330 LEU B CD1  1 
ATOM   5356 C  CD2  . LEU B 1 330 ? 99.453  116.844 110.191 1.00 56.56  ? 330 LEU B CD2  1 
ATOM   5357 N  N    . GLY B 1 331 ? 104.468 118.320 108.503 1.00 50.39  ? 331 GLY B N    1 
ATOM   5358 C  CA   . GLY B 1 331 ? 104.815 119.239 107.446 1.00 50.39  ? 331 GLY B CA   1 
ATOM   5359 C  C    . GLY B 1 331 ? 105.579 118.591 106.312 1.00 50.39  ? 331 GLY B C    1 
ATOM   5360 O  O    . GLY B 1 331 ? 105.062 118.439 105.204 1.00 50.39  ? 331 GLY B O    1 
ATOM   5361 N  N    . PRO B 1 332 ? 106.836 118.213 106.558 1.00 49.64  ? 332 PRO B N    1 
ATOM   5362 C  CA   . PRO B 1 332 ? 107.589 117.491 105.525 1.00 49.64  ? 332 PRO B CA   1 
ATOM   5363 C  C    . PRO B 1 332 ? 106.956 116.171 105.158 1.00 49.64  ? 332 PRO B C    1 
ATOM   5364 O  O    . PRO B 1 332 ? 106.960 115.791 103.980 1.00 49.64  ? 332 PRO B O    1 
ATOM   5365 C  CB   . PRO B 1 332 ? 108.964 117.284 106.169 1.00 49.64  ? 332 PRO B CB   1 
ATOM   5366 C  CG   . PRO B 1 332 ? 109.027 118.258 107.257 1.00 49.64  ? 332 PRO B CG   1 
ATOM   5367 C  CD   . PRO B 1 332 ? 107.642 118.416 107.764 1.00 49.64  ? 332 PRO B CD   1 
ATOM   5368 N  N    . GLY B 1 333 ? 106.384 115.475 106.140 1.00 51.09  ? 333 GLY B N    1 
ATOM   5369 C  CA   . GLY B 1 333 ? 105.794 114.178 105.875 1.00 51.09  ? 333 GLY B CA   1 
ATOM   5370 C  C    . GLY B 1 333 ? 104.700 114.241 104.835 1.00 51.09  ? 333 GLY B C    1 
ATOM   5371 O  O    . GLY B 1 333 ? 104.584 113.335 104.004 1.00 51.09  ? 333 GLY B O    1 
ATOM   5372 N  N    . LEU B 1 334 ? 103.921 115.327 104.836 1.00 50.53  ? 334 LEU B N    1 
ATOM   5373 C  CA   . LEU B 1 334 ? 102.915 115.535 103.804 1.00 50.53  ? 334 LEU B CA   1 
ATOM   5374 C  C    . LEU B 1 334 ? 103.539 115.470 102.419 1.00 50.53  ? 334 LEU B C    1 
ATOM   5375 O  O    . LEU B 1 334 ? 103.067 114.719 101.554 1.00 50.53  ? 334 LEU B O    1 
ATOM   5376 C  CB   . LEU B 1 334 ? 102.218 116.875 104.016 1.00 50.53  ? 334 LEU B CB   1 
ATOM   5377 C  CG   . LEU B 1 334 ? 100.759 116.892 103.585 1.00 50.53  ? 334 LEU B CG   1 
ATOM   5378 C  CD1  . LEU B 1 334 ? 99.961  116.009 104.513 1.00 50.53  ? 334 LEU B CD1  1 
ATOM   5379 C  CD2  . LEU B 1 334 ? 100.210 118.300 103.582 1.00 50.53  ? 334 LEU B CD2  1 
ATOM   5380 N  N    . LEU B 1 335 ? 104.642 116.203 102.212 1.00 48.36  ? 335 LEU B N    1 
ATOM   5381 C  CA   . LEU B 1 335 ? 105.381 116.115 100.956 1.00 48.36  ? 335 LEU B CA   1 
ATOM   5382 C  C    . LEU B 1 335 ? 105.724 114.675 100.639 1.00 48.36  ? 335 LEU B C    1 
ATOM   5383 O  O    . LEU B 1 335 ? 105.467 114.195 99.527  1.00 48.36  ? 335 LEU B O    1 
ATOM   5384 C  CB   . LEU B 1 335 ? 106.661 116.945 101.016 1.00 48.36  ? 335 LEU B CB   1 
ATOM   5385 C  CG   . LEU B 1 335 ? 106.582 118.460 100.917 1.00 48.36  ? 335 LEU B CG   1 
ATOM   5386 C  CD1  . LEU B 1 335 ? 107.945 119.047 101.167 1.00 48.36  ? 335 LEU B CD1  1 
ATOM   5387 C  CD2  . LEU B 1 335 ? 106.112 118.839 99.550  1.00 48.36  ? 335 LEU B CD2  1 
ATOM   5388 N  N    . PHE B 1 336 ? 106.236 113.954 101.641 1.00 48.17  ? 336 PHE B N    1 
ATOM   5389 C  CA   . PHE B 1 336 ? 106.584 112.553 101.468 1.00 48.17  ? 336 PHE B CA   1 
ATOM   5390 C  C    . PHE B 1 336 ? 105.406 111.766 100.929 1.00 48.17  ? 336 PHE B C    1 
ATOM   5391 O  O    . PHE B 1 336 ? 105.524 111.065 99.918  1.00 48.17  ? 336 PHE B O    1 
ATOM   5392 C  CB   . PHE B 1 336 ? 107.050 111.977 102.798 1.00 48.17  ? 336 PHE B CB   1 
ATOM   5393 C  CG   . PHE B 1 336 ? 107.854 110.732 102.666 1.00 48.17  ? 336 PHE B CG   1 
ATOM   5394 C  CD1  . PHE B 1 336 ? 109.062 110.747 102.015 1.00 48.17  ? 336 PHE B CD1  1 
ATOM   5395 C  CD2  . PHE B 1 336 ? 107.404 109.549 103.205 1.00 48.17  ? 336 PHE B CD2  1 
ATOM   5396 C  CE1  . PHE B 1 336 ? 109.806 109.605 101.902 1.00 48.17  ? 336 PHE B CE1  1 
ATOM   5397 C  CE2  . PHE B 1 336 ? 108.144 108.404 103.093 1.00 48.17  ? 336 PHE B CE2  1 
ATOM   5398 C  CZ   . PHE B 1 336 ? 109.345 108.431 102.437 1.00 48.17  ? 336 PHE B CZ   1 
ATOM   5399 N  N    . LEU B 1 337 ? 104.232 111.943 101.543 1.00 52.26  ? 337 LEU B N    1 
ATOM   5400 C  CA   . LEU B 1 337 ? 103.060 111.230 101.061 1.00 52.26  ? 337 LEU B CA   1 
ATOM   5401 C  C    . LEU B 1 337 ? 102.706 111.667 99.651  1.00 52.26  ? 337 LEU B C    1 
ATOM   5402 O  O    . LEU B 1 337 ? 102.470 110.826 98.776  1.00 52.26  ? 337 LEU B O    1 
ATOM   5403 C  CB   . LEU B 1 337 ? 101.885 111.443 102.009 1.00 52.26  ? 337 LEU B CB   1 
ATOM   5404 C  CG   . LEU B 1 337 ? 102.030 110.731 103.351 1.00 52.26  ? 337 LEU B CG   1 
ATOM   5405 C  CD1  . LEU B 1 337 ? 100.743 110.846 104.135 1.00 52.26  ? 337 LEU B CD1  1 
ATOM   5406 C  CD2  . LEU B 1 337 ? 102.413 109.282 103.151 1.00 52.26  ? 337 LEU B CD2  1 
ATOM   5407 N  N    . ASP B 1 338 ? 102.739 112.974 99.388  1.00 56.31  ? 338 ASP B N    1 
ATOM   5408 C  CA   . ASP B 1 338 ? 102.388 113.437 98.057  1.00 56.31  ? 338 ASP B CA   1 
ATOM   5409 C  C    . ASP B 1 338 ? 103.496 113.071 97.075  1.00 56.31  ? 338 ASP B C    1 
ATOM   5410 O  O    . ASP B 1 338 ? 103.278 113.068 95.863  1.00 56.31  ? 338 ASP B O    1 
ATOM   5411 C  CB   . ASP B 1 338 ? 102.108 114.943 98.113  1.00 56.31  ? 338 ASP B CB   1 
ATOM   5412 C  CG   . ASP B 1 338 ? 101.500 115.506 96.833  1.00 56.31  ? 338 ASP B CG   1 
ATOM   5413 O  OD1  . ASP B 1 338 ? 101.291 114.783 95.846  1.00 56.31  ? 338 ASP B OD1  1 
ATOM   5414 O  OD2  . ASP B 1 338 ? 101.185 116.709 96.824  1.00 56.31  ? 338 ASP B OD2  1 
ATOM   5415 N  N    . GLN B 1 339 ? 104.670 112.698 97.576  1.00 51.91  ? 339 GLN B N    1 
ATOM   5416 C  CA   . GLN B 1 339 ? 105.673 112.121 96.702  1.00 51.91  ? 339 GLN B CA   1 
ATOM   5417 C  C    . GLN B 1 339 ? 105.650 110.610 96.704  1.00 51.91  ? 339 GLN B C    1 
ATOM   5418 O  O    . GLN B 1 339 ? 106.181 110.004 95.766  1.00 51.91  ? 339 GLN B O    1 
ATOM   5419 C  CB   . GLN B 1 339 ? 107.068 112.579 97.097  1.00 51.91  ? 339 GLN B CB   1 
ATOM   5420 C  CG   . GLN B 1 339 ? 107.341 113.975 96.706  1.00 51.91  ? 339 GLN B CG   1 
ATOM   5421 C  CD   . GLN B 1 339 ? 108.748 114.167 96.227  1.00 51.91  ? 339 GLN B CD   1 
ATOM   5422 O  OE1  . GLN B 1 339 ? 109.479 113.204 96.007  1.00 51.91  ? 339 GLN B OE1  1 
ATOM   5423 N  NE2  . GLN B 1 339 ? 109.137 115.417 96.042  1.00 51.91  ? 339 GLN B NE2  1 
ATOM   5424 N  N    . TYR B 1 340 ? 105.081 109.983 97.734  1.00 52.13  ? 340 TYR B N    1 
ATOM   5425 C  CA   . TYR B 1 340 ? 105.003 108.531 97.706  1.00 52.13  ? 340 TYR B CA   1 
ATOM   5426 C  C    . TYR B 1 340 ? 104.070 108.072 96.606  1.00 52.13  ? 340 TYR B C    1 
ATOM   5427 O  O    . TYR B 1 340 ? 104.363 107.106 95.896  1.00 52.13  ? 340 TYR B O    1 
ATOM   5428 C  CB   . TYR B 1 340 ? 104.537 107.963 99.037  1.00 52.13  ? 340 TYR B CB   1 
ATOM   5429 C  CG   . TYR B 1 340 ? 104.306 106.495 98.895  1.00 52.13  ? 340 TYR B CG   1 
ATOM   5430 C  CD1  . TYR B 1 340 ? 105.357 105.649 98.616  1.00 52.13  ? 340 TYR B CD1  1 
ATOM   5431 C  CD2  . TYR B 1 340 ? 103.035 105.965 98.959  1.00 52.13  ? 340 TYR B CD2  1 
ATOM   5432 C  CE1  . TYR B 1 340 ? 105.162 104.316 98.452  1.00 52.13  ? 340 TYR B CE1  1 
ATOM   5433 C  CE2  . TYR B 1 340 ? 102.828 104.627 98.790  1.00 52.13  ? 340 TYR B CE2  1 
ATOM   5434 C  CZ   . TYR B 1 340 ? 103.899 103.808 98.541  1.00 52.13  ? 340 TYR B CZ   1 
ATOM   5435 O  OH   . TYR B 1 340 ? 103.709 102.461 98.372  1.00 52.13  ? 340 TYR B OH   1 
ATOM   5436 N  N    . PHE B 1 341 ? 102.951 108.763 96.436  1.00 55.54  ? 341 PHE B N    1 
ATOM   5437 C  CA   . PHE B 1 341 ? 102.081 108.511 95.300  1.00 55.54  ? 341 PHE B CA   1 
ATOM   5438 C  C    . PHE B 1 341 ? 102.713 109.191 94.092  1.00 55.54  ? 341 PHE B C    1 
ATOM   5439 O  O    . PHE B 1 341 ? 103.840 109.686 94.147  1.00 55.54  ? 341 PHE B O    1 
ATOM   5440 C  CB   . PHE B 1 341 ? 100.683 109.053 95.564  1.00 55.54  ? 341 PHE B CB   1 
ATOM   5441 C  CG   . PHE B 1 341 ? 100.096 108.610 96.863  1.00 55.54  ? 341 PHE B CG   1 
ATOM   5442 C  CD1  . PHE B 1 341 ? 99.918  107.274 97.148  1.00 55.54  ? 341 PHE B CD1  1 
ATOM   5443 C  CD2  . PHE B 1 341 ? 99.693  109.544 97.792  1.00 55.54  ? 341 PHE B CD2  1 
ATOM   5444 C  CE1  . PHE B 1 341 ? 99.376  106.882 98.354  1.00 55.54  ? 341 PHE B CE1  1 
ATOM   5445 C  CE2  . PHE B 1 341 ? 99.145  109.160 98.989  1.00 55.54  ? 341 PHE B CE2  1 
ATOM   5446 C  CZ   . PHE B 1 341 ? 98.987  107.831 99.274  1.00 55.54  ? 341 PHE B CZ   1 
ATOM   5447 N  N    . ASN B 1 342 ? 101.992 109.253 92.984  1.00 63.23  ? 342 ASN B N    1 
ATOM   5448 C  CA   . ASN B 1 342 ? 102.360 110.262 92.018  1.00 63.23  ? 342 ASN B CA   1 
ATOM   5449 C  C    . ASN B 1 342 ? 101.955 111.625 92.558  1.00 63.23  ? 342 ASN B C    1 
ATOM   5450 O  O    . ASN B 1 342 ? 101.307 111.742 93.603  1.00 63.23  ? 342 ASN B O    1 
ATOM   5451 C  CB   . ASN B 1 342 ? 101.707 109.987 90.671  1.00 63.23  ? 342 ASN B CB   1 
ATOM   5452 C  CG   . ASN B 1 342 ? 102.216 108.717 90.039  1.00 63.23  ? 342 ASN B CG   1 
ATOM   5453 O  OD1  . ASN B 1 342 ? 103.389 108.373 90.176  1.00 63.23  ? 342 ASN B OD1  1 
ATOM   5454 N  ND2  . ASN B 1 342 ? 101.336 108.009 89.346  1.00 63.23  ? 342 ASN B ND2  1 
ATOM   5455 N  N    . ASN B 1 343 ? 102.312 112.676 91.830  1.00 69.87  ? 343 ASN B N    1 
ATOM   5456 C  CA   . ASN B 1 343 ? 102.042 114.028 92.304  1.00 69.87  ? 343 ASN B CA   1 
ATOM   5457 C  C    . ASN B 1 343 ? 100.546 113.786 92.135  1.00 69.87  ? 343 ASN B C    1 
ATOM   5458 O  O    . ASN B 1 343 ? 100.056 113.381 91.078  1.00 69.87  ? 343 ASN B O    1 
ATOM   5459 C  CB   . ASN B 1 343 ? 102.837 115.043 91.499  1.00 69.87  ? 343 ASN B CB   1 
ATOM   5460 C  CG   . ASN B 1 343 ? 104.329 114.884 91.694  1.00 69.87  ? 343 ASN B CG   1 
ATOM   5461 O  OD1  . ASN B 1 343 ? 104.824 113.772 91.861  1.00 69.87  ? 343 ASN B OD1  1 
ATOM   5462 N  ND2  . ASN B 1 343 ? 105.053 115.995 91.684  1.00 69.87  ? 343 ASN B ND2  1 
ATOM   5463 N  N    . PHE B 1 344 ? 99.816  114.031 93.228  1.00 72.12  ? 344 PHE B N    1 
ATOM   5464 C  CA   . PHE B 1 344 ? 98.380  113.785 93.263  1.00 72.12  ? 344 PHE B CA   1 
ATOM   5465 C  C    . PHE B 1 344 ? 97.906  115.223 93.399  1.00 72.12  ? 344 PHE B C    1 
ATOM   5466 O  O    . PHE B 1 344 ? 96.920  115.620 92.771  1.00 72.12  ? 344 PHE B O    1 
ATOM   5467 C  CB   . PHE B 1 344 ? 97.863  112.931 94.416  1.00 72.12  ? 344 PHE B CB   1 
ATOM   5468 C  CG   . PHE B 1 344 ? 96.420  113.154 94.738  1.00 72.12  ? 344 PHE B CG   1 
ATOM   5469 C  CD1  . PHE B 1 344 ? 95.438  112.909 93.795  1.00 72.12  ? 344 PHE B CD1  1 
ATOM   5470 C  CD2  . PHE B 1 344 ? 96.042  113.591 95.994  1.00 72.12  ? 344 PHE B CD2  1 
ATOM   5471 C  CE1  . PHE B 1 344 ? 94.103  113.108 94.097  1.00 72.12  ? 344 PHE B CE1  1 
ATOM   5472 C  CE2  . PHE B 1 344 ? 94.711  113.791 96.301  1.00 72.12  ? 344 PHE B CE2  1 
ATOM   5473 C  CZ   . PHE B 1 344 ? 93.739  113.549 95.352  1.00 72.12  ? 344 PHE B CZ   1 
ATOM   5474 N  N    . ILE B 1 345 ? 98.585  116.006 94.223  1.00 64.76  ? 345 ILE B N    1 
ATOM   5475 C  CA   . ILE B 1 345 ? 98.427  117.449 94.246  1.00 64.76  ? 345 ILE B CA   1 
ATOM   5476 C  C    . ILE B 1 345 ? 99.738  118.047 93.765  1.00 64.76  ? 345 ILE B C    1 
ATOM   5477 O  O    . ILE B 1 345 ? 100.810 117.466 93.974  1.00 64.76  ? 345 ILE B O    1 
ATOM   5478 C  CB   . ILE B 1 345 ? 98.049  117.956 95.652  1.00 64.76  ? 345 ILE B CB   1 
ATOM   5479 C  CG1  . ILE B 1 345 ? 96.975  117.054 96.256  1.00 64.76  ? 345 ILE B CG1  1 
ATOM   5480 C  CG2  . ILE B 1 345 ? 97.500  119.360 95.577  1.00 64.76  ? 345 ILE B CG2  1 
ATOM   5481 C  CD1  . ILE B 1 345 ? 96.485  117.495 97.618  1.00 64.76  ? 345 ILE B CD1  1 
ATOM   5482 N  N    . ASP B 1 346 ? 99.650  119.186 93.078  1.00 63.35  ? 346 ASP B N    1 
ATOM   5483 C  CA   . ASP B 1 346 ? 100.841 119.844 92.550  1.00 63.35  ? 346 ASP B CA   1 
ATOM   5484 C  C    . ASP B 1 346 ? 101.802 120.185 93.680  1.00 63.35  ? 346 ASP B C    1 
ATOM   5485 O  O    . ASP B 1 346 ? 101.400 120.732 94.710  1.00 63.35  ? 346 ASP B O    1 
ATOM   5486 C  CB   . ASP B 1 346 ? 100.456 121.110 91.791  1.00 63.35  ? 346 ASP B CB   1 
ATOM   5487 C  CG   . ASP B 1 346 ? 101.444 121.455 90.700  1.00 63.35  ? 346 ASP B CG   1 
ATOM   5488 O  OD1  . ASP B 1 346 ? 102.458 120.741 90.572  1.00 63.35  ? 346 ASP B OD1  1 
ATOM   5489 O  OD2  . ASP B 1 346 ? 101.203 122.439 89.970  1.00 63.35  ? 346 ASP B OD2  1 
ATOM   5490 N  N    . GLU B 1 347 ? 103.079 119.855 93.479  1.00 60.04  ? 347 GLU B N    1 
ATOM   5491 C  CA   . GLU B 1 347 ? 104.027 119.826 94.590  1.00 60.04  ? 347 GLU B CA   1 
ATOM   5492 C  C    . GLU B 1 347 ? 104.279 121.205 95.172  1.00 60.04  ? 347 GLU B C    1 
ATOM   5493 O  O    . GLU B 1 347 ? 104.539 121.328 96.373  1.00 60.04  ? 347 GLU B O    1 
ATOM   5494 C  CB   . GLU B 1 347 ? 105.340 119.219 94.134  1.00 60.04  ? 347 GLU B CB   1 
ATOM   5495 C  CG   . GLU B 1 347 ? 106.116 118.587 95.240  1.00 60.04  ? 347 GLU B CG   1 
ATOM   5496 C  CD   . GLU B 1 347 ? 107.204 117.719 94.703  1.00 60.04  ? 347 GLU B CD   1 
ATOM   5497 O  OE1  . GLU B 1 347 ? 107.141 116.501 94.919  1.00 60.04  ? 347 GLU B OE1  1 
ATOM   5498 O  OE2  . GLU B 1 347 ? 108.108 118.251 94.030  1.00 60.04  ? 347 GLU B OE2  1 
ATOM   5499 N  N    . TYR B 1 348 ? 104.226 122.243 94.348  1.00 54.72  ? 348 TYR B N    1 
ATOM   5500 C  CA   . TYR B 1 348 ? 104.403 123.593 94.862  1.00 54.72  ? 348 TYR B CA   1 
ATOM   5501 C  C    . TYR B 1 348 ? 103.284 123.959 95.831  1.00 54.72  ? 348 TYR B C    1 
ATOM   5502 O  O    . TYR B 1 348 ? 103.530 124.570 96.881  1.00 54.72  ? 348 TYR B O    1 
ATOM   5503 C  CB   . TYR B 1 348 ? 104.499 124.567 93.689  1.00 54.72  ? 348 TYR B CB   1 
ATOM   5504 C  CG   . TYR B 1 348 ? 104.201 126.004 94.008  1.00 54.72  ? 348 TYR B CG   1 
ATOM   5505 C  CD1  . TYR B 1 348 ? 105.148 126.819 94.594  1.00 54.72  ? 348 TYR B CD1  1 
ATOM   5506 C  CD2  . TYR B 1 348 ? 102.981 126.560 93.671  1.00 54.72  ? 348 TYR B CD2  1 
ATOM   5507 C  CE1  . TYR B 1 348 ? 104.870 128.138 94.873  1.00 54.72  ? 348 TYR B CE1  1 
ATOM   5508 C  CE2  . TYR B 1 348 ? 102.696 127.877 93.940  1.00 54.72  ? 348 TYR B CE2  1 
ATOM   5509 C  CZ   . TYR B 1 348 ? 103.642 128.662 94.542  1.00 54.72  ? 348 TYR B CZ   1 
ATOM   5510 O  OH   . TYR B 1 348 ? 103.356 129.978 94.810  1.00 54.72  ? 348 TYR B OH   1 
ATOM   5511 N  N    . VAL B 1 349 ? 102.055 123.539 95.530  1.00 55.68  ? 349 VAL B N    1 
ATOM   5512 C  CA   . VAL B 1 349 ? 100.924 123.882 96.385  1.00 55.68  ? 349 VAL B CA   1 
ATOM   5513 C  C    . VAL B 1 349 ? 100.989 123.124 97.705  1.00 55.68  ? 349 VAL B C    1 
ATOM   5514 O  O    . VAL B 1 349 ? 100.723 123.692 98.772  1.00 55.68  ? 349 VAL B O    1 
ATOM   5515 C  CB   . VAL B 1 349 ? 99.603  123.630 95.646  1.00 55.68  ? 349 VAL B CB   1 
ATOM   5516 C  CG1  . VAL B 1 349 ? 98.435  124.082 96.499  1.00 55.68  ? 349 VAL B CG1  1 
ATOM   5517 C  CG2  . VAL B 1 349 ? 99.602  124.380 94.341  1.00 55.68  ? 349 VAL B CG2  1 
ATOM   5518 N  N    . VAL B 1 350 ? 101.348 121.839 97.668  1.00 54.01  ? 350 VAL B N    1 
ATOM   5519 C  CA   . VAL B 1 350 ? 101.478 121.104 98.922  1.00 54.01  ? 350 VAL B CA   1 
ATOM   5520 C  C    . VAL B 1 350 ? 102.684 121.592 99.716  1.00 54.01  ? 350 VAL B C    1 
ATOM   5521 O  O    . VAL B 1 350 ? 102.683 121.534 100.949 1.00 54.01  ? 350 VAL B O    1 
ATOM   5522 C  CB   . VAL B 1 350 ? 101.524 119.586 98.667  1.00 54.01  ? 350 VAL B CB   1 
ATOM   5523 C  CG1  . VAL B 1 350 ? 102.833 119.179 98.051  1.00 54.01  ? 350 VAL B CG1  1 
ATOM   5524 C  CG2  . VAL B 1 350 ? 101.288 118.817 99.953  1.00 54.01  ? 350 VAL B CG2  1 
ATOM   5525 N  N    . LEU B 1 351 ? 103.714 122.109 99.042  1.00 50.22  ? 351 LEU B N    1 
ATOM   5526 C  CA   . LEU B 1 351 ? 104.831 122.705 99.763  1.00 50.22  ? 351 LEU B CA   1 
ATOM   5527 C  C    . LEU B 1 351 ? 104.395 123.963 100.497 1.00 50.22  ? 351 LEU B C    1 
ATOM   5528 O  O    . LEU B 1 351 ? 104.801 124.191 101.640 1.00 50.22  ? 351 LEU B O    1 
ATOM   5529 C  CB   . LEU B 1 351 ? 105.973 123.016 98.802  1.00 50.22  ? 351 LEU B CB   1 
ATOM   5530 C  CG   . LEU B 1 351 ? 107.202 123.632 99.443  1.00 50.22  ? 351 LEU B CG   1 
ATOM   5531 C  CD1  . LEU B 1 351 ? 107.800 122.650 100.404 1.00 50.22  ? 351 LEU B CD1  1 
ATOM   5532 C  CD2  . LEU B 1 351 ? 108.195 123.988 98.385  1.00 50.22  ? 351 LEU B CD2  1 
ATOM   5533 N  N    . TRP B 1 352 ? 103.566 124.789 99.862  1.00 50.06  ? 352 TRP B N    1 
ATOM   5534 C  CA   . TRP B 1 352 ? 103.040 125.960 100.559 1.00 50.06  ? 352 TRP B CA   1 
ATOM   5535 C  C    . TRP B 1 352 ? 102.111 125.569 101.698 1.00 50.06  ? 352 TRP B C    1 
ATOM   5536 O  O    . TRP B 1 352 ? 102.087 126.229 102.745 1.00 50.06  ? 352 TRP B O    1 
ATOM   5537 C  CB   . TRP B 1 352 ? 102.325 126.874 99.581  1.00 50.06  ? 352 TRP B CB   1 
ATOM   5538 C  CG   . TRP B 1 352 ? 103.145 128.025 99.212  1.00 50.06  ? 352 TRP B CG   1 
ATOM   5539 C  CD1  . TRP B 1 352 ? 103.905 128.160 98.104  1.00 50.06  ? 352 TRP B CD1  1 
ATOM   5540 C  CD2  . TRP B 1 352 ? 103.293 129.230 99.955  1.00 50.06  ? 352 TRP B CD2  1 
ATOM   5541 N  NE1  . TRP B 1 352 ? 104.527 129.378 98.102  1.00 50.06  ? 352 TRP B NE1  1 
ATOM   5542 C  CE2  . TRP B 1 352 ? 104.165 130.055 99.234  1.00 50.06  ? 352 TRP B CE2  1 
ATOM   5543 C  CE3  . TRP B 1 352 ? 102.771 129.692 101.161 1.00 50.06  ? 352 TRP B CE3  1 
ATOM   5544 C  CZ2  . TRP B 1 352 ? 104.529 131.316 99.675  1.00 50.06  ? 352 TRP B CZ2  1 
ATOM   5545 C  CZ3  . TRP B 1 352 ? 103.132 130.943 101.598 1.00 50.06  ? 352 TRP B CZ3  1 
ATOM   5546 C  CH2  . TRP B 1 352 ? 104.004 131.742 100.859 1.00 50.06  ? 352 TRP B CH2  1 
ATOM   5547 N  N    . MET B 1 353 ? 101.327 124.507 101.516 1.00 54.85  ? 353 MET B N    1 
ATOM   5548 C  CA   . MET B 1 353 ? 100.505 124.026 102.620 1.00 54.85  ? 353 MET B CA   1 
ATOM   5549 C  C    . MET B 1 353 ? 101.376 123.550 103.775 1.00 54.85  ? 353 MET B C    1 
ATOM   5550 O  O    . MET B 1 353 ? 101.046 123.778 104.946 1.00 54.85  ? 353 MET B O    1 
ATOM   5551 C  CB   . MET B 1 353 ? 99.564  122.919 102.150 1.00 54.85  ? 353 MET B CB   1 
ATOM   5552 C  CG   . MET B 1 353 ? 98.189  123.424 101.726 1.00 54.85  ? 353 MET B CG   1 
ATOM   5553 S  SD   . MET B 1 353 ? 97.251  124.154 103.086 1.00 54.85  ? 353 MET B SD   1 
ATOM   5554 C  CE   . MET B 1 353 ? 96.340  125.448 102.244 1.00 54.85  ? 353 MET B CE   1 
ATOM   5555 N  N    . ALA B 1 354 ? 102.496 122.895 103.465 1.00 50.47  ? 354 ALA B N    1 
ATOM   5556 C  CA   . ALA B 1 354 ? 103.418 122.458 104.505 1.00 50.47  ? 354 ALA B CA   1 
ATOM   5557 C  C    . ALA B 1 354 ? 104.049 123.645 105.220 1.00 50.47  ? 354 ALA B C    1 
ATOM   5558 O  O    . ALA B 1 354 ? 104.190 123.624 106.447 1.00 50.47  ? 354 ALA B O    1 
ATOM   5559 C  CB   . ALA B 1 354 ? 104.487 121.552 103.911 1.00 50.47  ? 354 ALA B CB   1 
ATOM   5560 N  N    . MET B 1 355 ? 104.447 124.675 104.468 1.00 51.01  ? 355 MET B N    1 
ATOM   5561 C  CA   . MET B 1 355 ? 104.801 125.975 105.034 1.00 51.01  ? 355 MET B CA   1 
ATOM   5562 C  C    . MET B 1 355 ? 103.793 126.456 106.064 1.00 51.01  ? 355 MET B C    1 
ATOM   5563 O  O    . MET B 1 355 ? 104.151 126.754 107.206 1.00 51.01  ? 355 MET B O    1 
ATOM   5564 C  CB   . MET B 1 355 ? 104.909 127.023 103.922 1.00 51.01  ? 355 MET B CB   1 
ATOM   5565 C  CG   . MET B 1 355 ? 105.504 128.378 104.321 1.00 51.01  ? 355 MET B CG   1 
ATOM   5566 S  SD   . MET B 1 355 ? 106.817 128.489 105.531 1.00 51.01  ? 355 MET B SD   1 
ATOM   5567 C  CE   . MET B 1 355 ? 108.036 127.482 104.736 1.00 51.01  ? 355 MET B CE   1 
ATOM   5568 N  N    . VAL B 1 356 ? 102.522 126.530 105.669 1.00 54.30  ? 356 VAL B N    1 
ATOM   5569 C  CA   . VAL B 1 356 ? 101.514 127.110 106.552 1.00 54.30  ? 356 VAL B CA   1 
ATOM   5570 C  C    . VAL B 1 356 ? 101.324 126.251 107.799 1.00 54.30  ? 356 VAL B C    1 
ATOM   5571 O  O    . VAL B 1 356 ? 101.321 126.766 108.927 1.00 54.30  ? 356 VAL B O    1 
ATOM   5572 C  CB   . VAL B 1 356 ? 100.197 127.326 105.791 1.00 54.30  ? 356 VAL B CB   1 
ATOM   5573 C  CG1  . VAL B 1 356 ? 99.038  127.477 106.759 1.00 54.30  ? 356 VAL B CG1  1 
ATOM   5574 C  CG2  . VAL B 1 356 ? 100.304 128.560 104.925 1.00 54.30  ? 356 VAL B CG2  1 
ATOM   5575 N  N    . ILE B 1 357 ? 101.207 124.930 107.628 1.00 54.56  ? 357 ILE B N    1 
ATOM   5576 C  CA   . ILE B 1 357 ? 100.914 124.081 108.781 1.00 54.56  ? 357 ILE B CA   1 
ATOM   5577 C  C    . ILE B 1 357 ? 102.104 124.027 109.737 1.00 54.56  ? 357 ILE B C    1 
ATOM   5578 O  O    . ILE B 1 357 ? 101.935 124.135 110.959 1.00 54.56  ? 357 ILE B O    1 
ATOM   5579 C  CB   . ILE B 1 357 ? 100.453 122.677 108.337 1.00 54.56  ? 357 ILE B CB   1 
ATOM   5580 C  CG1  . ILE B 1 357 ? 100.090 121.829 109.550 1.00 54.56  ? 357 ILE B CG1  1 
ATOM   5581 C  CG2  . ILE B 1 357 ? 101.501 121.949 107.536 1.00 54.56  ? 357 ILE B CG2  1 
ATOM   5582 C  CD1  . ILE B 1 357 ? 99.614  120.439 109.194 1.00 54.56  ? 357 ILE B CD1  1 
ATOM   5583 N  N    . SER B 1 358 ? 103.326 123.906 109.209 1.00 54.63  ? 358 SER B N    1 
ATOM   5584 C  CA   . SER B 1 358 ? 104.496 123.862 110.073 1.00 54.63  ? 358 SER B CA   1 
ATOM   5585 C  C    . SER B 1 358 ? 104.726 125.198 110.762 1.00 54.63  ? 358 SER B C    1 
ATOM   5586 O  O    . SER B 1 358 ? 105.082 125.233 111.943 1.00 54.63  ? 358 SER B O    1 
ATOM   5587 C  CB   . SER B 1 358 ? 105.725 123.453 109.273 1.00 54.63  ? 358 SER B CB   1 
ATOM   5588 O  OG   . SER B 1 358 ? 106.904 123.736 109.997 1.00 54.63  ? 358 SER B OG   1 
ATOM   5589 N  N    . SER B 1 359 ? 104.520 126.307 110.046 1.00 55.90  ? 359 SER B N    1 
ATOM   5590 C  CA   . SER B 1 359 ? 104.695 127.617 110.655 1.00 55.90  ? 359 SER B CA   1 
ATOM   5591 C  C    . SER B 1 359 ? 103.710 127.839 111.792 1.00 55.90  ? 359 SER B C    1 
ATOM   5592 O  O    . SER B 1 359 ? 104.106 128.286 112.876 1.00 55.90  ? 359 SER B O    1 
ATOM   5593 C  CB   . SER B 1 359 ? 104.544 128.704 109.597 1.00 55.90  ? 359 SER B CB   1 
ATOM   5594 O  OG   . SER B 1 359 ? 104.563 129.989 110.188 1.00 55.90  ? 359 SER B OG   1 
ATOM   5595 N  N    . PHE B 1 360 ? 102.426 127.526 111.577 1.00 60.75  ? 360 PHE B N    1 
ATOM   5596 C  CA   . PHE B 1 360 ? 101.468 127.679 112.667 1.00 60.75  ? 360 PHE B CA   1 
ATOM   5597 C  C    . PHE B 1 360 ? 101.771 126.758 113.837 1.00 60.75  ? 360 PHE B C    1 
ATOM   5598 O  O    . PHE B 1 360 ? 101.667 127.184 114.990 1.00 60.75  ? 360 PHE B O    1 
ATOM   5599 C  CB   . PHE B 1 360 ? 100.031 127.472 112.195 1.00 60.75  ? 360 PHE B CB   1 
ATOM   5600 C  CG   . PHE B 1 360 ? 99.417  128.680 111.568 1.00 60.75  ? 360 PHE B CG   1 
ATOM   5601 C  CD1  . PHE B 1 360 ? 98.955  129.709 112.369 1.00 60.75  ? 360 PHE B CD1  1 
ATOM   5602 C  CD2  . PHE B 1 360 ? 99.259  128.779 110.202 1.00 60.75  ? 360 PHE B CD2  1 
ATOM   5603 C  CE1  . PHE B 1 360 ? 98.372  130.826 111.820 1.00 60.75  ? 360 PHE B CE1  1 
ATOM   5604 C  CE2  . PHE B 1 360 ? 98.673  129.897 109.646 1.00 60.75  ? 360 PHE B CE2  1 
ATOM   5605 C  CZ   . PHE B 1 360 ? 98.228  130.922 110.458 1.00 60.75  ? 360 PHE B CZ   1 
ATOM   5606 N  N    . ASP B 1 361 ? 102.142 125.500 113.582 1.00 64.11  ? 361 ASP B N    1 
ATOM   5607 C  CA   . ASP B 1 361 ? 102.413 124.614 114.711 1.00 64.11  ? 361 ASP B CA   1 
ATOM   5608 C  C    . ASP B 1 361 ? 103.634 125.072 115.501 1.00 64.11  ? 361 ASP B C    1 
ATOM   5609 O  O    . ASP B 1 361 ? 103.612 125.067 116.739 1.00 64.11  ? 361 ASP B O    1 
ATOM   5610 C  CB   . ASP B 1 361 ? 102.563 123.171 114.241 1.00 64.11  ? 361 ASP B CB   1 
ATOM   5611 C  CG   . ASP B 1 361 ? 101.251 122.407 114.290 1.00 64.11  ? 361 ASP B CG   1 
ATOM   5612 O  OD1  . ASP B 1 361 ? 100.377 122.780 115.097 1.00 64.11  ? 361 ASP B OD1  1 
ATOM   5613 O  OD2  . ASP B 1 361 ? 101.094 121.427 113.535 1.00 64.11  ? 361 ASP B OD2  1 
ATOM   5614 N  N    . MET B 1 362 ? 104.689 125.518 114.813 1.00 61.19  ? 362 MET B N    1 
ATOM   5615 C  CA   . MET B 1 362 ? 105.868 126.015 115.514 1.00 61.19  ? 362 MET B CA   1 
ATOM   5616 C  C    . MET B 1 362 ? 105.548 127.269 116.316 1.00 61.19  ? 362 MET B C    1 
ATOM   5617 O  O    . MET B 1 362 ? 105.937 127.384 117.486 1.00 61.19  ? 362 MET B O    1 
ATOM   5618 C  CB   . MET B 1 362 ? 106.991 126.295 114.519 1.00 61.19  ? 362 MET B CB   1 
ATOM   5619 C  CG   . MET B 1 362 ? 108.350 126.515 115.159 1.00 61.19  ? 362 MET B CG   1 
ATOM   5620 S  SD   . MET B 1 362 ? 108.684 128.232 115.586 1.00 61.19  ? 362 MET B SD   1 
ATOM   5621 C  CE   . MET B 1 362 ? 109.642 128.750 114.173 1.00 61.19  ? 362 MET B CE   1 
ATOM   5622 N  N    . VAL B 1 363 ? 104.843 128.222 115.704 1.00 61.03  ? 363 VAL B N    1 
ATOM   5623 C  CA   . VAL B 1 363 ? 104.539 129.473 116.387 1.00 61.03  ? 363 VAL B CA   1 
ATOM   5624 C  C    . VAL B 1 363 ? 103.637 129.224 117.588 1.00 61.03  ? 363 VAL B C    1 
ATOM   5625 O  O    . VAL B 1 363 ? 103.851 129.790 118.670 1.00 61.03  ? 363 VAL B O    1 
ATOM   5626 C  CB   . VAL B 1 363 ? 103.920 130.473 115.396 1.00 61.03  ? 363 VAL B CB   1 
ATOM   5627 C  CG1  . VAL B 1 363 ? 103.130 131.544 116.119 1.00 61.03  ? 363 VAL B CG1  1 
ATOM   5628 C  CG2  . VAL B 1 363 ? 105.007 131.102 114.562 1.00 61.03  ? 363 VAL B CG2  1 
ATOM   5629 N  N    . ILE B 1 364 ? 102.629 128.364 117.427 1.00 66.19  ? 364 ILE B N    1 
ATOM   5630 C  CA   . ILE B 1 364 ? 101.722 128.054 118.525 1.00 66.19  ? 364 ILE B CA   1 
ATOM   5631 C  C    . ILE B 1 364 ? 102.471 127.377 119.661 1.00 66.19  ? 364 ILE B C    1 
ATOM   5632 O  O    . ILE B 1 364 ? 102.298 127.744 120.831 1.00 66.19  ? 364 ILE B O    1 
ATOM   5633 C  CB   . ILE B 1 364 ? 100.550 127.198 118.015 1.00 66.19  ? 364 ILE B CB   1 
ATOM   5634 C  CG1  . ILE B 1 364 ? 99.547  128.083 117.278 1.00 66.19  ? 364 ILE B CG1  1 
ATOM   5635 C  CG2  . ILE B 1 364 ? 99.877  126.464 119.151 1.00 66.19  ? 364 ILE B CG2  1 
ATOM   5636 C  CD1  . ILE B 1 364 ? 99.004  129.216 118.120 1.00 66.19  ? 364 ILE B CD1  1 
ATOM   5637 N  N    . TYR B 1 365 ? 103.345 126.419 119.342 1.00 66.56  ? 365 TYR B N    1 
ATOM   5638 C  CA   . TYR B 1 365 ? 104.120 125.756 120.385 1.00 66.56  ? 365 TYR B CA   1 
ATOM   5639 C  C    . TYR B 1 365 ? 105.001 126.743 121.129 1.00 66.56  ? 365 TYR B C    1 
ATOM   5640 O  O    . TYR B 1 365 ? 105.064 126.727 122.362 1.00 66.56  ? 365 TYR B O    1 
ATOM   5641 C  CB   . TYR B 1 365 ? 104.985 124.652 119.787 1.00 66.56  ? 365 TYR B CB   1 
ATOM   5642 C  CG   . TYR B 1 365 ? 106.103 124.231 120.708 1.00 66.56  ? 365 TYR B CG   1 
ATOM   5643 C  CD1  . TYR B 1 365 ? 105.844 123.482 121.837 1.00 66.56  ? 365 TYR B CD1  1 
ATOM   5644 C  CD2  . TYR B 1 365 ? 107.416 124.585 120.450 1.00 66.56  ? 365 TYR B CD2  1 
ATOM   5645 C  CE1  . TYR B 1 365 ? 106.853 123.094 122.680 1.00 66.56  ? 365 TYR B CE1  1 
ATOM   5646 C  CE2  . TYR B 1 365 ? 108.430 124.201 121.293 1.00 66.56  ? 365 TYR B CE2  1 
ATOM   5647 C  CZ   . TYR B 1 365 ? 108.139 123.455 122.405 1.00 66.56  ? 365 TYR B CZ   1 
ATOM   5648 O  OH   . TYR B 1 365 ? 109.142 123.064 123.254 1.00 66.56  ? 365 TYR B OH   1 
ATOM   5649 N  N    . PHE B 1 366 ? 105.682 127.620 120.396 1.00 72.15  ? 366 PHE B N    1 
ATOM   5650 C  CA   . PHE B 1 366 ? 106.639 128.511 121.039 1.00 72.15  ? 366 PHE B CA   1 
ATOM   5651 C  C    . PHE B 1 366 ? 105.942 129.559 121.898 1.00 72.15  ? 366 PHE B C    1 
ATOM   5652 O  O    . PHE B 1 366 ? 106.369 129.829 123.031 1.00 72.15  ? 366 PHE B O    1 
ATOM   5653 C  CB   . PHE B 1 366 ? 107.518 129.164 119.978 1.00 72.15  ? 366 PHE B CB   1 
ATOM   5654 C  CG   . PHE B 1 366 ? 108.773 129.745 120.522 1.00 72.15  ? 366 PHE B CG   1 
ATOM   5655 C  CD1  . PHE B 1 366 ? 109.525 129.038 121.436 1.00 72.15  ? 366 PHE B CD1  1 
ATOM   5656 C  CD2  . PHE B 1 366 ? 109.220 130.977 120.101 1.00 72.15  ? 366 PHE B CD2  1 
ATOM   5657 C  CE1  . PHE B 1 366 ? 110.686 129.559 121.941 1.00 72.15  ? 366 PHE B CE1  1 
ATOM   5658 C  CE2  . PHE B 1 366 ? 110.382 131.504 120.601 1.00 72.15  ? 366 PHE B CE2  1 
ATOM   5659 C  CZ   . PHE B 1 366 ? 111.117 130.794 121.523 1.00 72.15  ? 366 PHE B CZ   1 
ATOM   5660 N  N    . SER B 1 367 ? 104.860 130.151 121.387 1.00 78.89  ? 367 SER B N    1 
ATOM   5661 C  CA   . SER B 1 367 ? 104.125 131.128 122.177 1.00 78.89  ? 367 SER B CA   1 
ATOM   5662 C  C    . SER B 1 367 ? 103.464 130.479 123.384 1.00 78.89  ? 367 SER B C    1 
ATOM   5663 O  O    . SER B 1 367 ? 103.432 131.074 124.467 1.00 78.89  ? 367 SER B O    1 
ATOM   5664 C  CB   . SER B 1 367 ? 103.094 131.843 121.311 1.00 78.89  ? 367 SER B CB   1 
ATOM   5665 O  OG   . SER B 1 367 ? 103.717 132.836 120.521 1.00 78.89  ? 367 SER B OG   1 
ATOM   5666 N  N    . ALA B 1 368 ? 102.945 129.259 123.230 1.00 82.16  ? 368 ALA B N    1 
ATOM   5667 C  CA   . ALA B 1 368 ? 102.370 128.559 124.373 1.00 82.16  ? 368 ALA B CA   1 
ATOM   5668 C  C    . ALA B 1 368 ? 103.432 128.266 125.419 1.00 82.16  ? 368 ALA B C    1 
ATOM   5669 O  O    . ALA B 1 368 ? 103.174 128.388 126.622 1.00 82.16  ? 368 ALA B O    1 
ATOM   5670 C  CB   . ALA B 1 368 ? 101.703 127.268 123.914 1.00 82.16  ? 368 ALA B CB   1 
ATOM   5671 N  N    . LEU B 1 369 ? 104.632 127.889 124.981 1.00 83.07  ? 369 LEU B N    1 
ATOM   5672 C  CA   . LEU B 1 369 ? 105.716 127.619 125.914 1.00 83.07  ? 369 LEU B CA   1 
ATOM   5673 C  C    . LEU B 1 369 ? 106.080 128.865 126.703 1.00 83.07  ? 369 LEU B C    1 
ATOM   5674 O  O    . LEU B 1 369 ? 106.188 128.827 127.935 1.00 83.07  ? 369 LEU B O    1 
ATOM   5675 C  CB   . LEU B 1 369 ? 106.932 127.099 125.160 1.00 83.07  ? 369 LEU B CB   1 
ATOM   5676 C  CG   . LEU B 1 369 ? 108.030 126.540 126.050 1.00 83.07  ? 369 LEU B CG   1 
ATOM   5677 C  CD1  . LEU B 1 369 ? 107.559 125.265 126.681 1.00 83.07  ? 369 LEU B CD1  1 
ATOM   5678 C  CD2  . LEU B 1 369 ? 109.263 126.297 125.231 1.00 83.07  ? 369 LEU B CD2  1 
ATOM   5679 N  N    . CYS B 1 370 ? 106.268 129.988 126.005 1.00 92.75  ? 370 CYS B N    1 
ATOM   5680 C  CA   . CYS B 1 370 ? 106.634 131.208 126.716 1.00 92.75  ? 370 CYS B CA   1 
ATOM   5681 C  C    . CYS B 1 370 ? 105.512 131.674 127.634 1.00 92.75  ? 370 CYS B C    1 
ATOM   5682 O  O    . CYS B 1 370 ? 105.780 132.142 128.747 1.00 92.75  ? 370 CYS B O    1 
ATOM   5683 C  CB   . CYS B 1 370 ? 107.016 132.316 125.735 1.00 92.75  ? 370 CYS B CB   1 
ATOM   5684 S  SG   . CYS B 1 370 ? 105.628 133.275 125.094 1.00 92.75  ? 370 CYS B SG   1 
ATOM   5685 N  N    . LEU B 1 371 ? 104.255 131.530 127.204 1.00 91.35  ? 371 LEU B N    1 
ATOM   5686 C  CA   . LEU B 1 371 ? 103.134 131.930 128.045 1.00 91.35  ? 371 LEU B CA   1 
ATOM   5687 C  C    . LEU B 1 371 ? 103.047 131.075 129.301 1.00 91.35  ? 371 LEU B C    1 
ATOM   5688 O  O    . LEU B 1 371 ? 102.799 131.598 130.391 1.00 91.35  ? 371 LEU B O    1 
ATOM   5689 C  CB   . LEU B 1 371 ? 101.831 131.852 127.255 1.00 91.35  ? 371 LEU B CB   1 
ATOM   5690 C  CG   . LEU B 1 371 ? 101.530 133.062 126.372 1.00 91.35  ? 371 LEU B CG   1 
ATOM   5691 C  CD1  . LEU B 1 371 ? 100.183 132.901 125.695 1.00 91.35  ? 371 LEU B CD1  1 
ATOM   5692 C  CD2  . LEU B 1 371 ? 101.576 134.337 127.188 1.00 91.35  ? 371 LEU B CD2  1 
ATOM   5693 N  N    . GLN B 1 372 ? 103.249 129.760 129.172 1.00 97.03  ? 372 GLN B N    1 
ATOM   5694 C  CA   . GLN B 1 372 ? 103.215 128.896 130.348 1.00 97.03  ? 372 GLN B CA   1 
ATOM   5695 C  C    . GLN B 1 372 ? 104.354 129.213 131.301 1.00 97.03  ? 372 GLN B C    1 
ATOM   5696 O  O    . GLN B 1 372 ? 104.157 129.237 132.522 1.00 97.03  ? 372 GLN B O    1 
ATOM   5697 C  CB   . GLN B 1 372 ? 103.274 127.428 129.939 1.00 97.03  ? 372 GLN B CB   1 
ATOM   5698 C  CG   . GLN B 1 372 ? 102.999 126.486 131.091 1.00 97.03  ? 372 GLN B CG   1 
ATOM   5699 C  CD   . GLN B 1 372 ? 103.397 125.061 130.795 1.00 97.03  ? 372 GLN B CD   1 
ATOM   5700 O  OE1  . GLN B 1 372 ? 103.757 124.726 129.672 1.00 97.03  ? 372 GLN B OE1  1 
ATOM   5701 N  NE2  . GLN B 1 372 ? 103.338 124.211 131.808 1.00 97.03  ? 372 GLN B NE2  1 
ATOM   5702 N  N    . ILE B 1 373 ? 105.554 129.457 130.766 1.00 101.25 ? 373 ILE B N    1 
ATOM   5703 C  CA   . ILE B 1 373 ? 106.684 129.789 131.624 1.00 101.25 ? 373 ILE B CA   1 
ATOM   5704 C  C    . ILE B 1 373 ? 106.424 131.099 132.356 1.00 101.25 ? 373 ILE B C    1 
ATOM   5705 O  O    . ILE B 1 373 ? 106.715 131.229 133.551 1.00 101.25 ? 373 ILE B O    1 
ATOM   5706 C  CB   . ILE B 1 373 ? 107.984 129.842 130.802 1.00 101.25 ? 373 ILE B CB   1 
ATOM   5707 C  CG1  . ILE B 1 373 ? 108.325 128.456 130.260 1.00 101.25 ? 373 ILE B CG1  1 
ATOM   5708 C  CG2  . ILE B 1 373 ? 109.130 130.363 131.642 1.00 101.25 ? 373 ILE B CG2  1 
ATOM   5709 C  CD1  . ILE B 1 373 ? 108.778 127.501 131.307 1.00 101.25 ? 373 ILE B CD1  1 
ATOM   5710 N  N    . SER B 1 374 ? 105.855 132.082 131.656 1.00 107.27 ? 374 SER B N    1 
ATOM   5711 C  CA   . SER B 1 374 ? 105.547 133.361 132.289 1.00 107.27 ? 374 SER B CA   1 
ATOM   5712 C  C    . SER B 1 374 ? 104.470 133.218 133.358 1.00 107.27 ? 374 SER B C    1 
ATOM   5713 O  O    . SER B 1 374 ? 104.574 133.818 134.433 1.00 107.27 ? 374 SER B O    1 
ATOM   5714 C  CB   . SER B 1 374 ? 105.109 134.370 131.232 1.00 107.27 ? 374 SER B CB   1 
ATOM   5715 O  OG   . SER B 1 374 ? 103.735 134.205 130.930 1.00 107.27 ? 374 SER B OG   1 
ATOM   5716 N  N    . ARG B 1 375 ? 103.432 132.427 133.084 1.00 111.53 ? 375 ARG B N    1 
ATOM   5717 C  CA   . ARG B 1 375 ? 102.316 132.328 134.018 1.00 111.53 ? 375 ARG B CA   1 
ATOM   5718 C  C    . ARG B 1 375 ? 102.684 131.524 135.255 1.00 111.53 ? 375 ARG B C    1 
ATOM   5719 O  O    . ARG B 1 375 ? 102.244 131.854 136.362 1.00 111.53 ? 375 ARG B O    1 
ATOM   5720 C  CB   . ARG B 1 375 ? 101.101 131.715 133.324 1.00 111.53 ? 375 ARG B CB   1 
ATOM   5721 C  CG   . ARG B 1 375 ? 100.177 132.734 132.674 1.00 111.53 ? 375 ARG B CG   1 
ATOM   5722 C  CD   . ARG B 1 375 ? 98.999  132.061 131.990 1.00 111.53 ? 375 ARG B CD   1 
ATOM   5723 N  NE   . ARG B 1 375 ? 98.280  132.976 131.110 1.00 111.53 ? 375 ARG B NE   1 
ATOM   5724 C  CZ   . ARG B 1 375 ? 97.229  133.699 131.487 1.00 111.53 ? 375 ARG B CZ   1 
ATOM   5725 N  NH1  . ARG B 1 375 ? 96.771  133.610 132.727 1.00 111.53 ? 375 ARG B NH1  1 
ATOM   5726 N  NH2  . ARG B 1 375 ? 96.634  134.510 130.622 1.00 111.53 ? 375 ARG B NH2  1 
ATOM   5727 N  N    . HIS B 1 376 ? 103.476 130.462 135.092 1.00 109.65 ? 376 HIS B N    1 
ATOM   5728 C  CA   . HIS B 1 376 ? 103.849 129.644 136.244 1.00 109.65 ? 376 HIS B CA   1 
ATOM   5729 C  C    . HIS B 1 376 ? 104.723 130.416 137.220 1.00 109.65 ? 376 HIS B C    1 
ATOM   5730 O  O    . HIS B 1 376 ? 104.560 130.298 138.438 1.00 109.65 ? 376 HIS B O    1 
ATOM   5731 C  CB   . HIS B 1 376 ? 104.570 128.381 135.789 1.00 109.65 ? 376 HIS B CB   1 
ATOM   5732 C  CG   . HIS B 1 376 ? 105.296 127.683 136.893 1.00 109.65 ? 376 HIS B CG   1 
ATOM   5733 N  ND1  . HIS B 1 376 ? 106.658 127.782 137.067 1.00 109.65 ? 376 HIS B ND1  1 
ATOM   5734 C  CD2  . HIS B 1 376 ? 104.850 126.881 137.887 1.00 109.65 ? 376 HIS B CD2  1 
ATOM   5735 C  CE1  . HIS B 1 376 ? 107.021 127.074 138.119 1.00 109.65 ? 376 HIS B CE1  1 
ATOM   5736 N  NE2  . HIS B 1 376 ? 105.943 126.512 138.633 1.00 109.65 ? 376 HIS B NE2  1 
ATOM   5737 N  N    . LEU B 1 377 ? 105.655 131.213 136.707 1.00 112.22 ? 377 LEU B N    1 
ATOM   5738 C  CA   . LEU B 1 377 ? 106.534 131.998 137.559 1.00 112.22 ? 377 LEU B CA   1 
ATOM   5739 C  C    . LEU B 1 377 ? 105.898 133.302 138.020 1.00 112.22 ? 377 LEU B C    1 
ATOM   5740 O  O    . LEU B 1 377 ? 106.526 134.025 138.803 1.00 112.22 ? 377 LEU B O    1 
ATOM   5741 C  CB   . LEU B 1 377 ? 107.842 132.292 136.826 1.00 112.22 ? 377 LEU B CB   1 
ATOM   5742 C  CG   . LEU B 1 377 ? 108.617 131.058 136.367 1.00 112.22 ? 377 LEU B CG   1 
ATOM   5743 C  CD1  . LEU B 1 377 ? 109.885 131.462 135.636 1.00 112.22 ? 377 LEU B CD1  1 
ATOM   5744 C  CD2  . LEU B 1 377 ? 108.940 130.175 137.554 1.00 112.22 ? 377 LEU B CD2  1 
ATOM   5745 N  N    . HIS B 1 378 ? 104.678 133.602 137.560 1.00 118.13 ? 378 HIS B N    1 
ATOM   5746 C  CA   . HIS B 1 378 ? 103.981 134.853 137.864 1.00 118.13 ? 378 HIS B CA   1 
ATOM   5747 C  C    . HIS B 1 378 ? 104.834 136.064 137.490 1.00 118.13 ? 378 HIS B C    1 
ATOM   5748 O  O    . HIS B 1 378 ? 104.912 137.054 138.220 1.00 118.13 ? 378 HIS B O    1 
ATOM   5749 C  CB   . HIS B 1 378 ? 103.552 134.911 139.334 1.00 118.13 ? 378 HIS B CB   1 
ATOM   5750 C  CG   . HIS B 1 378 ? 102.465 135.903 139.604 1.00 118.13 ? 378 HIS B CG   1 
ATOM   5751 N  ND1  . HIS B 1 378 ? 101.278 135.917 138.904 1.00 118.13 ? 378 HIS B ND1  1 
ATOM   5752 C  CD2  . HIS B 1 378 ? 102.391 136.925 140.489 1.00 118.13 ? 378 HIS B CD2  1 
ATOM   5753 C  CE1  . HIS B 1 378 ? 100.515 136.900 139.352 1.00 118.13 ? 378 HIS B CE1  1 
ATOM   5754 N  NE2  . HIS B 1 378 ? 101.168 137.526 140.314 1.00 118.13 ? 378 HIS B NE2  1 
ATOM   5755 N  N    . LEU B 1 379 ? 105.490 135.976 136.337 1.00 120.48 ? 379 LEU B N    1 
ATOM   5756 C  CA   . LEU B 1 379 ? 106.348 137.036 135.836 1.00 120.48 ? 379 LEU B CA   1 
ATOM   5757 C  C    . LEU B 1 379 ? 105.903 137.430 134.437 1.00 120.48 ? 379 LEU B C    1 
ATOM   5758 O  O    . LEU B 1 379 ? 105.582 136.570 133.611 1.00 120.48 ? 379 LEU B O    1 
ATOM   5759 C  CB   . LEU B 1 379 ? 107.813 136.597 135.811 1.00 120.48 ? 379 LEU B CB   1 
ATOM   5760 C  CG   . LEU B 1 379 ? 108.827 137.727 135.652 1.00 120.48 ? 379 LEU B CG   1 
ATOM   5761 C  CD1  . LEU B 1 379 ? 108.867 138.579 136.911 1.00 120.48 ? 379 LEU B CD1  1 
ATOM   5762 C  CD2  . LEU B 1 379 ? 110.203 137.172 135.327 1.00 120.48 ? 379 LEU B CD2  1 
ATOM   5763 N  N    . ASN B 1 380 ? 105.879 138.733 134.178 1.00 124.21 ? 380 ASN B N    1 
ATOM   5764 C  CA   . ASN B 1 380 ? 105.548 139.224 132.850 1.00 124.21 ? 380 ASN B CA   1 
ATOM   5765 C  C    . ASN B 1 380 ? 106.656 138.872 131.865 1.00 124.21 ? 380 ASN B C    1 
ATOM   5766 O  O    . ASN B 1 380 ? 107.831 138.764 132.225 1.00 124.21 ? 380 ASN B O    1 
ATOM   5767 C  CB   . ASN B 1 380 ? 105.331 140.737 132.880 1.00 124.21 ? 380 ASN B CB   1 
ATOM   5768 C  CG   . ASN B 1 380 ? 104.446 141.221 131.747 1.00 124.21 ? 380 ASN B CG   1 
ATOM   5769 O  OD1  . ASN B 1 380 ? 103.749 140.433 131.107 1.00 124.21 ? 380 ASN B OD1  1 
ATOM   5770 N  ND2  . ASN B 1 380 ? 104.467 142.526 131.496 1.00 124.21 ? 380 ASN B ND2  1 
ATOM   5771 N  N    . ILE B 1 381 ? 106.264 138.681 130.603 1.00 121.43 ? 381 ILE B N    1 
ATOM   5772 C  CA   . ILE B 1 381 ? 107.247 138.411 129.557 1.00 121.43 ? 381 ILE B CA   1 
ATOM   5773 C  C    . ILE B 1 381 ? 108.147 139.620 129.339 1.00 121.43 ? 381 ILE B C    1 
ATOM   5774 O  O    . ILE B 1 381 ? 109.295 139.476 128.907 1.00 121.43 ? 381 ILE B O    1 
ATOM   5775 C  CB   . ILE B 1 381 ? 106.539 137.970 128.258 1.00 121.43 ? 381 ILE B CB   1 
ATOM   5776 C  CG1  . ILE B 1 381 ? 107.531 137.303 127.305 1.00 121.43 ? 381 ILE B CG1  1 
ATOM   5777 C  CG2  . ILE B 1 381 ? 105.824 139.134 127.589 1.00 121.43 ? 381 ILE B CG2  1 
ATOM   5778 C  CD1  . ILE B 1 381 ? 108.283 136.156 127.922 1.00 121.43 ? 381 ILE B CD1  1 
ATOM   5779 N  N    . PHE B 1 382 ? 107.657 140.819 129.645 1.00 121.52 ? 382 PHE B N    1 
ATOM   5780 C  CA   . PHE B 1 382 ? 108.445 142.039 129.561 1.00 121.52 ? 382 PHE B CA   1 
ATOM   5781 C  C    . PHE B 1 382 ? 108.492 142.684 130.936 1.00 121.52 ? 382 PHE B C    1 
ATOM   5782 O  O    . PHE B 1 382 ? 107.451 142.870 131.573 1.00 121.52 ? 382 PHE B O    1 
ATOM   5783 C  CB   . PHE B 1 382 ? 107.860 143.016 128.538 1.00 121.52 ? 382 PHE B CB   1 
ATOM   5784 C  CG   . PHE B 1 382 ? 107.494 142.381 127.227 1.00 121.52 ? 382 PHE B CG   1 
ATOM   5785 C  CD1  . PHE B 1 382 ? 108.390 141.561 126.562 1.00 121.52 ? 382 PHE B CD1  1 
ATOM   5786 C  CD2  . PHE B 1 382 ? 106.260 142.619 126.649 1.00 121.52 ? 382 PHE B CD2  1 
ATOM   5787 C  CE1  . PHE B 1 382 ? 108.057 140.979 125.356 1.00 121.52 ? 382 PHE B CE1  1 
ATOM   5788 C  CE2  . PHE B 1 382 ? 105.923 142.046 125.440 1.00 121.52 ? 382 PHE B CE2  1 
ATOM   5789 C  CZ   . PHE B 1 382 ? 106.822 141.224 124.793 1.00 121.52 ? 382 PHE B CZ   1 
ATOM   5790 N  N    . LYS B 1 383 ? 109.693 143.024 131.391 1.00 118.11 ? 383 LYS B N    1 
ATOM   5791 C  CA   . LYS B 1 383 ? 109.852 143.661 132.689 1.00 118.11 ? 383 LYS B CA   1 
ATOM   5792 C  C    . LYS B 1 383 ? 110.460 145.051 132.549 1.00 118.11 ? 383 LYS B C    1 
ATOM   5793 O  O    . LYS B 1 383 ? 109.926 146.027 133.075 1.00 118.11 ? 383 LYS B O    1 
ATOM   5794 C  CB   . LYS B 1 383 ? 110.719 142.801 133.607 1.00 118.11 ? 383 LYS B CB   1 
ATOM   5795 C  CG   . LYS B 1 383 ? 111.135 143.497 134.891 1.00 118.11 ? 383 LYS B CG   1 
ATOM   5796 C  CD   . LYS B 1 383 ? 111.932 142.571 135.794 1.00 118.11 ? 383 LYS B CD   1 
ATOM   5797 C  CE   . LYS B 1 383 ? 111.247 141.224 135.938 1.00 118.11 ? 383 LYS B CE   1 
ATOM   5798 N  NZ   . LYS B 1 383 ? 111.961 140.329 136.888 1.00 118.11 ? 383 LYS B NZ   1 
HETATM 5799 N  N    . POV C 2 .   ? 85.726  78.723  122.246 1.00 79.19  ? 501 POV A N    1 
HETATM 5800 P  P    . POV C 2 .   ? 89.439  81.431  121.778 1.00 79.19  ? 501 POV A P    1 
HETATM 5801 C  C1   . POV C 2 .   ? 90.250  83.254  120.064 1.00 79.19  ? 501 POV A C1   1 
HETATM 5802 C  C2   . POV C 2 .   ? 89.399  83.561  118.828 1.00 79.19  ? 501 POV A C2   1 
HETATM 5803 C  C3   . POV C 2 .   ? 90.288  83.726  117.583 1.00 79.19  ? 501 POV A C3   1 
HETATM 5804 C  C210 . POV C 2 .   ? 80.794  87.346  111.463 1.00 79.19  ? 501 POV A C210 1 
HETATM 5805 C  C310 . POV C 2 .   ? 87.550  85.194  105.388 1.00 79.19  ? 501 POV A C310 1 
HETATM 5806 C  C11  . POV C 2 .   ? 88.065  79.417  122.762 1.00 79.19  ? 501 POV A C11  1 
HETATM 5807 O  O11  . POV C 2 .   ? 90.121  81.868  120.329 1.00 79.19  ? 501 POV A O11  1 
HETATM 5808 C  C211 . POV C 2 .   ? 81.478  86.364  110.494 1.00 79.19  ? 501 POV A C211 1 
HETATM 5809 C  C311 . POV C 2 .   ? 87.747  84.489  104.021 1.00 79.19  ? 501 POV A C311 1 
HETATM 5810 C  C12  . POV C 2 .   ? 86.570  79.849  122.750 1.00 79.19  ? 501 POV A C12  1 
HETATM 5811 O  O12  . POV C 2 .   ? 88.689  79.961  121.613 1.00 79.19  ? 501 POV A O12  1 
HETATM 5812 C  C212 . POV C 2 .   ? 80.564  85.143  110.202 1.00 79.19  ? 501 POV A C212 1 
HETATM 5813 C  C312 . POV C 2 .   ? 86.413  84.308  103.263 1.00 79.19  ? 501 POV A C312 1 
HETATM 5814 C  C13  . POV C 2 .   ? 86.154  77.957  121.049 1.00 79.19  ? 501 POV A C13  1 
HETATM 5815 O  O13  . POV C 2 .   ? 90.513  81.315  122.829 1.00 79.19  ? 501 POV A O13  1 
HETATM 5816 C  C213 . POV C 2 .   ? 79.752  85.279  108.885 1.00 79.19  ? 501 POV A C213 1 
HETATM 5817 C  C313 . POV C 2 .   ? 86.635  83.879  101.789 1.00 79.19  ? 501 POV A C313 1 
HETATM 5818 C  C14  . POV C 2 .   ? 85.629  77.748  123.351 1.00 79.19  ? 501 POV A C14  1 
HETATM 5819 O  O14  . POV C 2 .   ? 88.429  82.474  122.185 1.00 79.19  ? 501 POV A O14  1 
HETATM 5820 C  C214 . POV C 2 .   ? 78.906  84.009  108.600 1.00 79.19  ? 501 POV A C214 1 
HETATM 5821 C  C314 . POV C 2 .   ? 85.370  84.098  100.925 1.00 79.19  ? 501 POV A C314 1 
HETATM 5822 C  C15  . POV C 2 .   ? 84.401  79.298  121.938 1.00 79.19  ? 501 POV A C15  1 
HETATM 5823 C  C215 . POV C 2 .   ? 78.731  83.722  107.087 1.00 79.19  ? 501 POV A C215 1 
HETATM 5824 C  C315 . POV C 2 .   ? 84.159  83.323  101.482 1.00 79.19  ? 501 POV A C315 1 
HETATM 5825 C  C216 . POV C 2 .   ? 80.021  84.019  106.281 1.00 79.19  ? 501 POV A C216 1 
HETATM 5826 C  C316 . POV C 2 .   ? 84.096  81.884  100.932 1.00 79.19  ? 501 POV A C316 1 
HETATM 5827 C  C217 . POV C 2 .   ? 80.676  82.755  105.675 1.00 79.19  ? 501 POV A C217 1 
HETATM 5828 C  C218 . POV C 2 .   ? 82.220  82.829  105.726 1.00 79.19  ? 501 POV A C218 1 
HETATM 5829 C  C21  . POV C 2 .   ? 89.143  85.970  118.801 1.00 79.19  ? 501 POV A C21  1 
HETATM 5830 O  O21  . POV C 2 .   ? 88.596  84.687  119.068 1.00 79.19  ? 501 POV A O21  1 
HETATM 5831 C  C22  . POV C 2 .   ? 88.540  86.846  117.666 1.00 79.19  ? 501 POV A C22  1 
HETATM 5832 O  O22  . POV C 2 .   ? 90.038  86.390  119.450 1.00 79.19  ? 501 POV A O22  1 
HETATM 5833 C  C23  . POV C 2 .   ? 86.993  86.784  117.645 1.00 79.19  ? 501 POV A C23  1 
HETATM 5834 C  C24  . POV C 2 .   ? 86.466  86.616  116.193 1.00 79.19  ? 501 POV A C24  1 
HETATM 5835 C  C25  . POV C 2 .   ? 85.186  87.446  115.913 1.00 79.19  ? 501 POV A C25  1 
HETATM 5836 C  C26  . POV C 2 .   ? 84.691  87.165  114.473 1.00 79.19  ? 501 POV A C26  1 
HETATM 5837 C  C27  . POV C 2 .   ? 83.190  87.460  114.240 1.00 79.19  ? 501 POV A C27  1 
HETATM 5838 C  C28  . POV C 2 .   ? 82.910  87.742  112.746 1.00 79.19  ? 501 POV A C28  1 
HETATM 5839 C  C29  . POV C 2 .   ? 81.417  87.963  112.466 1.00 79.19  ? 501 POV A C29  1 
HETATM 5840 C  C31  . POV C 2 .   ? 90.030  82.690  115.458 1.00 79.19  ? 501 POV A C31  1 
HETATM 5841 O  O31  . POV C 2 .   ? 89.471  83.560  116.431 1.00 79.19  ? 501 POV A O31  1 
HETATM 5842 C  C32  . POV C 2 .   ? 89.693  82.860  113.960 1.00 79.19  ? 501 POV A C32  1 
HETATM 5843 O  O32  . POV C 2 .   ? 90.752  81.815  115.793 1.00 79.19  ? 501 POV A O32  1 
HETATM 5844 C  C33  . POV C 2 .   ? 89.480  84.341  113.536 1.00 79.19  ? 501 POV A C33  1 
HETATM 5845 C  C34  . POV C 2 .   ? 88.457  84.484  112.371 1.00 79.19  ? 501 POV A C34  1 
HETATM 5846 C  C35  . POV C 2 .   ? 88.755  85.703  111.456 1.00 79.19  ? 501 POV A C35  1 
HETATM 5847 C  C36  . POV C 2 .   ? 89.372  85.267  110.103 1.00 79.19  ? 501 POV A C36  1 
HETATM 5848 C  C37  . POV C 2 .   ? 88.293  84.890  109.053 1.00 79.19  ? 501 POV A C37  1 
HETATM 5849 C  C38  . POV C 2 .   ? 88.536  85.609  107.700 1.00 79.19  ? 501 POV A C38  1 
HETATM 5850 C  C39  . POV C 2 .   ? 88.494  84.645  106.488 1.00 79.19  ? 501 POV A C39  1 
HETATM 5851 MG MG   . MG  D 3 .   ? 91.593  80.013  121.749 1.00 30.00  ? 502 MG  A MG   1 
HETATM 5852 MG MG   . MG  E 3 .   ? 93.047  77.620  123.052 1.00 30.00  ? 503 MG  A MG   1 
HETATM 5853 N  N    . POV F 2 .   ? 128.275 135.278 122.248 1.00 79.19  ? 501 POV B N    1 
HETATM 5854 P  P    . POV F 2 .   ? 124.562 132.571 121.779 1.00 79.19  ? 501 POV B P    1 
HETATM 5855 C  C1   . POV F 2 .   ? 123.751 130.748 120.065 1.00 79.19  ? 501 POV B C1   1 
HETATM 5856 C  C2   . POV F 2 .   ? 124.602 130.441 118.829 1.00 79.19  ? 501 POV B C2   1 
HETATM 5857 C  C3   . POV F 2 .   ? 123.713 130.276 117.584 1.00 79.19  ? 501 POV B C3   1 
HETATM 5858 C  C210 . POV F 2 .   ? 133.208 126.656 111.465 1.00 79.19  ? 501 POV B C210 1 
HETATM 5859 C  C310 . POV F 2 .   ? 126.453 128.809 105.389 1.00 79.19  ? 501 POV B C310 1 
HETATM 5860 C  C11  . POV F 2 .   ? 125.936 134.585 122.763 1.00 79.19  ? 501 POV B C11  1 
HETATM 5861 O  O11  . POV F 2 .   ? 123.880 132.134 120.330 1.00 79.19  ? 501 POV B O11  1 
HETATM 5862 C  C211 . POV F 2 .   ? 132.524 127.638 110.496 1.00 79.19  ? 501 POV B C211 1 
HETATM 5863 C  C311 . POV F 2 .   ? 126.256 129.514 104.022 1.00 79.19  ? 501 POV B C311 1 
HETATM 5864 C  C12  . POV F 2 .   ? 127.431 134.152 122.752 1.00 79.19  ? 501 POV B C12  1 
HETATM 5865 O  O12  . POV F 2 .   ? 125.312 134.041 121.614 1.00 79.19  ? 501 POV B O12  1 
HETATM 5866 C  C212 . POV F 2 .   ? 133.438 128.859 110.204 1.00 79.19  ? 501 POV B C212 1 
HETATM 5867 C  C312 . POV F 2 .   ? 127.590 129.695 103.264 1.00 79.19  ? 501 POV B C312 1 
HETATM 5868 C  C13  . POV F 2 .   ? 127.848 136.044 121.051 1.00 79.19  ? 501 POV B C13  1 
HETATM 5869 O  O13  . POV F 2 .   ? 123.488 132.687 122.830 1.00 79.19  ? 501 POV B O13  1 
HETATM 5870 C  C213 . POV F 2 .   ? 134.250 128.723 108.887 1.00 79.19  ? 501 POV B C213 1 
HETATM 5871 C  C313 . POV F 2 .   ? 127.368 130.124 101.790 1.00 79.19  ? 501 POV B C313 1 
HETATM 5872 C  C14  . POV F 2 .   ? 128.372 136.253 123.353 1.00 79.19  ? 501 POV B C14  1 
HETATM 5873 O  O14  . POV F 2 .   ? 125.572 131.528 122.186 1.00 79.19  ? 501 POV B O14  1 
HETATM 5874 C  C214 . POV F 2 .   ? 135.096 129.993 108.602 1.00 79.19  ? 501 POV B C214 1 
HETATM 5875 C  C314 . POV F 2 .   ? 128.633 129.905 100.926 1.00 79.19  ? 501 POV B C314 1 
HETATM 5876 C  C15  . POV F 2 .   ? 129.600 134.703 121.940 1.00 79.19  ? 501 POV B C15  1 
HETATM 5877 C  C215 . POV F 2 .   ? 135.272 130.280 107.089 1.00 79.19  ? 501 POV B C215 1 
HETATM 5878 C  C315 . POV F 2 .   ? 129.844 130.680 101.484 1.00 79.19  ? 501 POV B C315 1 
HETATM 5879 C  C216 . POV F 2 .   ? 133.982 129.983 106.283 1.00 79.19  ? 501 POV B C216 1 
HETATM 5880 C  C316 . POV F 2 .   ? 129.908 132.119 100.934 1.00 79.19  ? 501 POV B C316 1 
HETATM 5881 C  C217 . POV F 2 .   ? 133.327 131.247 105.677 1.00 79.19  ? 501 POV B C217 1 
HETATM 5882 C  C218 . POV F 2 .   ? 131.783 131.173 105.728 1.00 79.19  ? 501 POV B C218 1 
HETATM 5883 C  C21  . POV F 2 .   ? 124.858 128.032 118.802 1.00 79.19  ? 501 POV B C21  1 
HETATM 5884 O  O21  . POV F 2 .   ? 125.405 129.315 119.069 1.00 79.19  ? 501 POV B O21  1 
HETATM 5885 C  C22  . POV F 2 .   ? 125.461 127.156 117.667 1.00 79.19  ? 501 POV B C22  1 
HETATM 5886 O  O22  . POV F 2 .   ? 123.963 127.612 119.451 1.00 79.19  ? 501 POV B O22  1 
HETATM 5887 C  C23  . POV F 2 .   ? 127.008 127.218 117.646 1.00 79.19  ? 501 POV B C23  1 
HETATM 5888 C  C24  . POV F 2 .   ? 127.535 127.386 116.194 1.00 79.19  ? 501 POV B C24  1 
HETATM 5889 C  C25  . POV F 2 .   ? 128.815 126.556 115.914 1.00 79.19  ? 501 POV B C25  1 
HETATM 5890 C  C26  . POV F 2 .   ? 129.310 126.837 114.474 1.00 79.19  ? 501 POV B C26  1 
HETATM 5891 C  C27  . POV F 2 .   ? 130.811 126.542 114.241 1.00 79.19  ? 501 POV B C27  1 
HETATM 5892 C  C28  . POV F 2 .   ? 131.092 126.260 112.747 1.00 79.19  ? 501 POV B C28  1 
HETATM 5893 C  C29  . POV F 2 .   ? 132.585 126.039 112.468 1.00 79.19  ? 501 POV B C29  1 
HETATM 5894 C  C31  . POV F 2 .   ? 123.972 131.312 115.459 1.00 79.19  ? 501 POV B C31  1 
HETATM 5895 O  O31  . POV F 2 .   ? 124.531 130.442 116.432 1.00 79.19  ? 501 POV B O31  1 
HETATM 5896 C  C32  . POV F 2 .   ? 124.309 131.142 113.961 1.00 79.19  ? 501 POV B C32  1 
HETATM 5897 O  O32  . POV F 2 .   ? 123.250 132.187 115.794 1.00 79.19  ? 501 POV B O32  1 
HETATM 5898 C  C33  . POV F 2 .   ? 124.522 129.661 113.537 1.00 79.19  ? 501 POV B C33  1 
HETATM 5899 C  C34  . POV F 2 .   ? 125.545 129.518 112.372 1.00 79.19  ? 501 POV B C34  1 
HETATM 5900 C  C35  . POV F 2 .   ? 125.247 128.300 111.457 1.00 79.19  ? 501 POV B C35  1 
HETATM 5901 C  C36  . POV F 2 .   ? 124.630 128.736 110.104 1.00 79.19  ? 501 POV B C36  1 
HETATM 5902 C  C37  . POV F 2 .   ? 125.709 129.113 109.054 1.00 79.19  ? 501 POV B C37  1 
HETATM 5903 C  C38  . POV F 2 .   ? 125.466 128.394 107.701 1.00 79.19  ? 501 POV B C38  1 
HETATM 5904 C  C39  . POV F 2 .   ? 125.509 129.358 106.489 1.00 79.19  ? 501 POV B C39  1 
HETATM 5905 MG MG   . MG  G 3 .   ? 122.408 133.989 121.750 1.00 30.00  ? 502 MG  B MG   1 
HETATM 5906 MG MG   . MG  H 3 .   ? 120.954 136.382 123.053 1.00 30.00  ? 503 MG  B MG   1 
# 
