data_9UDZ
# 
_entry.id   9UDZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9UDZ         pdb_00009udz 10.2210/pdb9udz/pdb 
WWPDB D_1300057087 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-05-21 ? 
2 'Structure model' 1 1 2025-06-11 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation_author.identifier_ORCID' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9UDZ 
_pdbx_database_status.recvd_initial_deposition_date   2025-04-07 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
3 yoshida.hiromi@kagawa-u.ac.jp Hiromi Yoshida ? 'principal investigator/group leader' 0000-0001-8333-8215 
4 wangsa.ismaya@dexa-medica.com Wangsa Ismaya  T 'principal investigator/group leader' 0000-0001-5467-5343 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Yoshida, H.'  1 0000-0001-8333-8215 
'Ismaya, W.T.' 2 0000-0001-5467-5343 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acta Crystallogr.,Sect.F' 
_citation.journal_id_ASTM           ACSFEN 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2053-230X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            81 
_citation.language                  ? 
_citation.page_first                241 
_citation.page_last                 248 
_citation.title                     
'Crystal structure of a recombinant Agaricus bisporus mushroom mannose-binding protein with a longer C-terminal region.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1107/S2053230X25003905 
_citation.pdbx_database_id_PubMed   40349189 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Yoshida, H.'         1 ? 
primary 'Nakakita, S.I.'      2 ? 
primary 'Rachmawati, H.'      3 ? 
primary 'Tjandrawinata, R.R.' 4 ? 
primary 'Ismaya, W.T.'        5 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Lectin-like fold protein' 18719.699 2  ? ? ? ? 
2 water   nat water                      18.015    23 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAQARKIPLDLPGTRILNGANWANNSATENLATNSGTLIIFDQSTPGQDADRWLIHNYLDGYKIFNMGSNNWASVSRGNT
VLGVSEFDGQTCKWSIEYSGNGEEFWIRVPREGGGGAVWTIKPASSQGPTTVFLDLLKETDPNQRIKFAVDPNSSVDKLA
AALEHHHHHH
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAQARKIPLDLPGTRILNGANWANNSATENLATNSGTLIIFDQSTPGQDADRWLIHNYLDGYKIFNMGSNNWASVSRGNT
VLGVSEFDGQTCKWSIEYSGNGEEFWIRVPREGGGGAVWTIKPASSQGPTTVFLDLLKETDPNQRIKFAVDPNSSVDKLA
AALEHHHHHH
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   GLN n 
1 4   ALA n 
1 5   ARG n 
1 6   LYS n 
1 7   ILE n 
1 8   PRO n 
1 9   LEU n 
1 10  ASP n 
1 11  LEU n 
1 12  PRO n 
1 13  GLY n 
1 14  THR n 
1 15  ARG n 
1 16  ILE n 
1 17  LEU n 
1 18  ASN n 
1 19  GLY n 
1 20  ALA n 
1 21  ASN n 
1 22  TRP n 
1 23  ALA n 
1 24  ASN n 
1 25  ASN n 
1 26  SER n 
1 27  ALA n 
1 28  THR n 
1 29  GLU n 
1 30  ASN n 
1 31  LEU n 
1 32  ALA n 
1 33  THR n 
1 34  ASN n 
1 35  SER n 
1 36  GLY n 
1 37  THR n 
1 38  LEU n 
1 39  ILE n 
1 40  ILE n 
1 41  PHE n 
1 42  ASP n 
1 43  GLN n 
1 44  SER n 
1 45  THR n 
1 46  PRO n 
1 47  GLY n 
1 48  GLN n 
1 49  ASP n 
1 50  ALA n 
1 51  ASP n 
1 52  ARG n 
1 53  TRP n 
1 54  LEU n 
1 55  ILE n 
1 56  HIS n 
1 57  ASN n 
1 58  TYR n 
1 59  LEU n 
1 60  ASP n 
1 61  GLY n 
1 62  TYR n 
1 63  LYS n 
1 64  ILE n 
1 65  PHE n 
1 66  ASN n 
1 67  MET n 
1 68  GLY n 
1 69  SER n 
1 70  ASN n 
1 71  ASN n 
1 72  TRP n 
1 73  ALA n 
1 74  SER n 
1 75  VAL n 
1 76  SER n 
1 77  ARG n 
1 78  GLY n 
1 79  ASN n 
1 80  THR n 
1 81  VAL n 
1 82  LEU n 
1 83  GLY n 
1 84  VAL n 
1 85  SER n 
1 86  GLU n 
1 87  PHE n 
1 88  ASP n 
1 89  GLY n 
1 90  GLN n 
1 91  THR n 
1 92  CYS n 
1 93  LYS n 
1 94  TRP n 
1 95  SER n 
1 96  ILE n 
1 97  GLU n 
1 98  TYR n 
1 99  SER n 
1 100 GLY n 
1 101 ASN n 
1 102 GLY n 
1 103 GLU n 
1 104 GLU n 
1 105 PHE n 
1 106 TRP n 
1 107 ILE n 
1 108 ARG n 
1 109 VAL n 
1 110 PRO n 
1 111 ARG n 
1 112 GLU n 
1 113 GLY n 
1 114 GLY n 
1 115 GLY n 
1 116 GLY n 
1 117 ALA n 
1 118 VAL n 
1 119 TRP n 
1 120 THR n 
1 121 ILE n 
1 122 LYS n 
1 123 PRO n 
1 124 ALA n 
1 125 SER n 
1 126 SER n 
1 127 GLN n 
1 128 GLY n 
1 129 PRO n 
1 130 THR n 
1 131 THR n 
1 132 VAL n 
1 133 PHE n 
1 134 LEU n 
1 135 ASP n 
1 136 LEU n 
1 137 LEU n 
1 138 LYS n 
1 139 GLU n 
1 140 THR n 
1 141 ASP n 
1 142 PRO n 
1 143 ASN n 
1 144 GLN n 
1 145 ARG n 
1 146 ILE n 
1 147 LYS n 
1 148 PHE n 
1 149 ALA n 
1 150 VAL n 
1 151 ASP n 
1 152 PRO n 
1 153 ASN n 
1 154 SER n 
1 155 SER n 
1 156 VAL n 
1 157 ASP n 
1 158 LYS n 
1 159 LEU n 
1 160 ALA n 
1 161 ALA n 
1 162 ALA n 
1 163 LEU n 
1 164 GLU n 
1 165 HIS n 
1 166 HIS n 
1 167 HIS n 
1 168 HIS n 
1 169 HIS n 
1 170 HIS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   170 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Agaricus bisporus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     5341 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pET28a 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ALA 4   4   ?   ?   ?   A . n 
A 1 5   ARG 5   5   ?   ?   ?   A . n 
A 1 6   LYS 6   6   6   LYS LYS A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   PRO 8   8   8   PRO PRO A . n 
A 1 9   LEU 9   9   9   LEU LEU A . n 
A 1 10  ASP 10  10  10  ASP ASP A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  PRO 12  12  12  PRO PRO A . n 
A 1 13  GLY 13  13  13  GLY GLY A . n 
A 1 14  THR 14  14  14  THR THR A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  ILE 16  16  16  ILE ILE A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  ASN 18  18  18  ASN ASN A . n 
A 1 19  GLY 19  19  19  GLY GLY A . n 
A 1 20  ALA 20  20  20  ALA ALA A . n 
A 1 21  ASN 21  21  21  ASN ASN A . n 
A 1 22  TRP 22  22  22  TRP TRP A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ASN 24  24  24  ASN ASN A . n 
A 1 25  ASN 25  25  25  ASN ASN A . n 
A 1 26  SER 26  26  26  SER SER A . n 
A 1 27  ALA 27  27  27  ALA ALA A . n 
A 1 28  THR 28  28  28  THR THR A . n 
A 1 29  GLU 29  29  29  GLU GLU A . n 
A 1 30  ASN 30  30  30  ASN ASN A . n 
A 1 31  LEU 31  31  ?   ?   ?   A . n 
A 1 32  ALA 32  32  ?   ?   ?   A . n 
A 1 33  THR 33  33  ?   ?   ?   A . n 
A 1 34  ASN 34  34  34  ASN ASN A . n 
A 1 35  SER 35  35  35  SER SER A . n 
A 1 36  GLY 36  36  36  GLY GLY A . n 
A 1 37  THR 37  37  37  THR THR A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  ILE 39  39  39  ILE ILE A . n 
A 1 40  ILE 40  40  40  ILE ILE A . n 
A 1 41  PHE 41  41  41  PHE PHE A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  GLN 43  43  43  GLN GLN A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  PRO 46  46  46  PRO PRO A . n 
A 1 47  GLY 47  47  47  GLY GLY A . n 
A 1 48  GLN 48  48  48  GLN GLN A . n 
A 1 49  ASP 49  49  49  ASP ASP A . n 
A 1 50  ALA 50  50  50  ALA ALA A . n 
A 1 51  ASP 51  51  51  ASP ASP A . n 
A 1 52  ARG 52  52  52  ARG ARG A . n 
A 1 53  TRP 53  53  53  TRP TRP A . n 
A 1 54  LEU 54  54  54  LEU LEU A . n 
A 1 55  ILE 55  55  55  ILE ILE A . n 
A 1 56  HIS 56  56  56  HIS HIS A . n 
A 1 57  ASN 57  57  57  ASN ASN A . n 
A 1 58  TYR 58  58  58  TYR TYR A . n 
A 1 59  LEU 59  59  59  LEU LEU A . n 
A 1 60  ASP 60  60  60  ASP ASP A . n 
A 1 61  GLY 61  61  61  GLY GLY A . n 
A 1 62  TYR 62  62  62  TYR TYR A . n 
A 1 63  LYS 63  63  63  LYS LYS A . n 
A 1 64  ILE 64  64  64  ILE ILE A . n 
A 1 65  PHE 65  65  65  PHE PHE A . n 
A 1 66  ASN 66  66  66  ASN ASN A . n 
A 1 67  MET 67  67  67  MET MET A . n 
A 1 68  GLY 68  68  68  GLY GLY A . n 
A 1 69  SER 69  69  69  SER SER A . n 
A 1 70  ASN 70  70  70  ASN ASN A . n 
A 1 71  ASN 71  71  71  ASN ASN A . n 
A 1 72  TRP 72  72  72  TRP TRP A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  SER 74  74  74  SER SER A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  SER 76  76  76  SER SER A . n 
A 1 77  ARG 77  77  77  ARG ARG A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  ASN 79  79  79  ASN ASN A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  VAL 81  81  81  VAL VAL A . n 
A 1 82  LEU 82  82  82  LEU LEU A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  SER 85  85  85  SER SER A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  PHE 87  87  87  PHE PHE A . n 
A 1 88  ASP 88  88  88  ASP ASP A . n 
A 1 89  GLY 89  89  89  GLY GLY A . n 
A 1 90  GLN 90  90  90  GLN GLN A . n 
A 1 91  THR 91  91  91  THR THR A . n 
A 1 92  CYS 92  92  92  CYS CYS A . n 
A 1 93  LYS 93  93  93  LYS LYS A . n 
A 1 94  TRP 94  94  94  TRP TRP A . n 
A 1 95  SER 95  95  95  SER SER A . n 
A 1 96  ILE 96  96  96  ILE ILE A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  TYR 98  98  98  TYR TYR A . n 
A 1 99  SER 99  99  99  SER SER A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 ASN 101 101 101 ASN ASN A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 PHE 105 105 105 PHE PHE A . n 
A 1 106 TRP 106 106 106 TRP TRP A . n 
A 1 107 ILE 107 107 107 ILE ILE A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 GLU 112 112 112 GLU GLU A . n 
A 1 113 GLY 113 113 113 GLY GLY A . n 
A 1 114 GLY 114 114 114 GLY GLY A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 GLY 116 116 116 GLY GLY A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 TRP 119 119 119 TRP TRP A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 LYS 122 122 122 LYS LYS A . n 
A 1 123 PRO 123 123 123 PRO PRO A . n 
A 1 124 ALA 124 124 ?   ?   ?   A . n 
A 1 125 SER 125 125 ?   ?   ?   A . n 
A 1 126 SER 126 126 ?   ?   ?   A . n 
A 1 127 GLN 127 127 ?   ?   ?   A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 PRO 129 129 129 PRO PRO A . n 
A 1 130 THR 130 130 130 THR THR A . n 
A 1 131 THR 131 131 131 THR THR A . n 
A 1 132 VAL 132 132 132 VAL VAL A . n 
A 1 133 PHE 133 133 133 PHE PHE A . n 
A 1 134 LEU 134 134 134 LEU LEU A . n 
A 1 135 ASP 135 135 135 ASP ASP A . n 
A 1 136 LEU 136 136 136 LEU LEU A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 LYS 138 138 138 LYS LYS A . n 
A 1 139 GLU 139 139 139 GLU GLU A . n 
A 1 140 THR 140 140 140 THR THR A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 PRO 142 142 142 PRO PRO A . n 
A 1 143 ASN 143 143 143 ASN ASN A . n 
A 1 144 GLN 144 144 144 GLN GLN A . n 
A 1 145 ARG 145 145 145 ARG ARG A . n 
A 1 146 ILE 146 146 146 ILE ILE A . n 
A 1 147 LYS 147 147 147 LYS LYS A . n 
A 1 148 PHE 148 148 148 PHE PHE A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 ASP 151 151 151 ASP ASP A . n 
A 1 152 PRO 152 152 ?   ?   ?   A . n 
A 1 153 ASN 153 153 ?   ?   ?   A . n 
A 1 154 SER 154 154 ?   ?   ?   A . n 
A 1 155 SER 155 155 ?   ?   ?   A . n 
A 1 156 VAL 156 156 ?   ?   ?   A . n 
A 1 157 ASP 157 157 ?   ?   ?   A . n 
A 1 158 LYS 158 158 ?   ?   ?   A . n 
A 1 159 LEU 159 159 ?   ?   ?   A . n 
A 1 160 ALA 160 160 ?   ?   ?   A . n 
A 1 161 ALA 161 161 ?   ?   ?   A . n 
A 1 162 ALA 162 162 ?   ?   ?   A . n 
A 1 163 LEU 163 163 ?   ?   ?   A . n 
A 1 164 GLU 164 164 ?   ?   ?   A . n 
A 1 165 HIS 165 165 ?   ?   ?   A . n 
A 1 166 HIS 166 166 ?   ?   ?   A . n 
A 1 167 HIS 167 167 ?   ?   ?   A . n 
A 1 168 HIS 168 168 ?   ?   ?   A . n 
A 1 169 HIS 169 169 ?   ?   ?   A . n 
A 1 170 HIS 170 170 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ALA 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ALA 4   4   ?   ?   ?   B . n 
B 1 5   ARG 5   5   ?   ?   ?   B . n 
B 1 6   LYS 6   6   6   LYS LYS B . n 
B 1 7   ILE 7   7   7   ILE ILE B . n 
B 1 8   PRO 8   8   8   PRO PRO B . n 
B 1 9   LEU 9   9   9   LEU LEU B . n 
B 1 10  ASP 10  10  10  ASP ASP B . n 
B 1 11  LEU 11  11  11  LEU LEU B . n 
B 1 12  PRO 12  12  12  PRO PRO B . n 
B 1 13  GLY 13  13  13  GLY GLY B . n 
B 1 14  THR 14  14  14  THR THR B . n 
B 1 15  ARG 15  15  15  ARG ARG B . n 
B 1 16  ILE 16  16  16  ILE ILE B . n 
B 1 17  LEU 17  17  17  LEU LEU B . n 
B 1 18  ASN 18  18  18  ASN ASN B . n 
B 1 19  GLY 19  19  19  GLY GLY B . n 
B 1 20  ALA 20  20  20  ALA ALA B . n 
B 1 21  ASN 21  21  21  ASN ASN B . n 
B 1 22  TRP 22  22  22  TRP TRP B . n 
B 1 23  ALA 23  23  23  ALA ALA B . n 
B 1 24  ASN 24  24  24  ASN ASN B . n 
B 1 25  ASN 25  25  25  ASN ASN B . n 
B 1 26  SER 26  26  26  SER SER B . n 
B 1 27  ALA 27  27  27  ALA ALA B . n 
B 1 28  THR 28  28  28  THR THR B . n 
B 1 29  GLU 29  29  29  GLU GLU B . n 
B 1 30  ASN 30  30  30  ASN ASN B . n 
B 1 31  LEU 31  31  ?   ?   ?   B . n 
B 1 32  ALA 32  32  ?   ?   ?   B . n 
B 1 33  THR 33  33  ?   ?   ?   B . n 
B 1 34  ASN 34  34  34  ASN ASN B . n 
B 1 35  SER 35  35  35  SER SER B . n 
B 1 36  GLY 36  36  36  GLY GLY B . n 
B 1 37  THR 37  37  37  THR THR B . n 
B 1 38  LEU 38  38  38  LEU LEU B . n 
B 1 39  ILE 39  39  39  ILE ILE B . n 
B 1 40  ILE 40  40  40  ILE ILE B . n 
B 1 41  PHE 41  41  41  PHE PHE B . n 
B 1 42  ASP 42  42  42  ASP ASP B . n 
B 1 43  GLN 43  43  43  GLN GLN B . n 
B 1 44  SER 44  44  44  SER SER B . n 
B 1 45  THR 45  45  45  THR THR B . n 
B 1 46  PRO 46  46  46  PRO PRO B . n 
B 1 47  GLY 47  47  47  GLY GLY B . n 
B 1 48  GLN 48  48  48  GLN GLN B . n 
B 1 49  ASP 49  49  49  ASP ASP B . n 
B 1 50  ALA 50  50  50  ALA ALA B . n 
B 1 51  ASP 51  51  51  ASP ASP B . n 
B 1 52  ARG 52  52  52  ARG ARG B . n 
B 1 53  TRP 53  53  53  TRP TRP B . n 
B 1 54  LEU 54  54  54  LEU LEU B . n 
B 1 55  ILE 55  55  55  ILE ILE B . n 
B 1 56  HIS 56  56  56  HIS HIS B . n 
B 1 57  ASN 57  57  57  ASN ASN B . n 
B 1 58  TYR 58  58  58  TYR TYR B . n 
B 1 59  LEU 59  59  59  LEU LEU B . n 
B 1 60  ASP 60  60  60  ASP ASP B . n 
B 1 61  GLY 61  61  61  GLY GLY B . n 
B 1 62  TYR 62  62  62  TYR TYR B . n 
B 1 63  LYS 63  63  63  LYS LYS B . n 
B 1 64  ILE 64  64  64  ILE ILE B . n 
B 1 65  PHE 65  65  65  PHE PHE B . n 
B 1 66  ASN 66  66  66  ASN ASN B . n 
B 1 67  MET 67  67  67  MET MET B . n 
B 1 68  GLY 68  68  68  GLY GLY B . n 
B 1 69  SER 69  69  69  SER SER B . n 
B 1 70  ASN 70  70  70  ASN ASN B . n 
B 1 71  ASN 71  71  71  ASN ASN B . n 
B 1 72  TRP 72  72  72  TRP TRP B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  SER 74  74  74  SER SER B . n 
B 1 75  VAL 75  75  75  VAL VAL B . n 
B 1 76  SER 76  76  76  SER SER B . n 
B 1 77  ARG 77  77  77  ARG ARG B . n 
B 1 78  GLY 78  78  78  GLY GLY B . n 
B 1 79  ASN 79  79  79  ASN ASN B . n 
B 1 80  THR 80  80  80  THR THR B . n 
B 1 81  VAL 81  81  81  VAL VAL B . n 
B 1 82  LEU 82  82  82  LEU LEU B . n 
B 1 83  GLY 83  83  83  GLY GLY B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  SER 85  85  85  SER SER B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  PHE 87  87  87  PHE PHE B . n 
B 1 88  ASP 88  88  88  ASP ASP B . n 
B 1 89  GLY 89  89  89  GLY GLY B . n 
B 1 90  GLN 90  90  90  GLN GLN B . n 
B 1 91  THR 91  91  91  THR THR B . n 
B 1 92  CYS 92  92  92  CYS CYS B . n 
B 1 93  LYS 93  93  93  LYS LYS B . n 
B 1 94  TRP 94  94  94  TRP TRP B . n 
B 1 95  SER 95  95  95  SER SER B . n 
B 1 96  ILE 96  96  96  ILE ILE B . n 
B 1 97  GLU 97  97  97  GLU GLU B . n 
B 1 98  TYR 98  98  98  TYR TYR B . n 
B 1 99  SER 99  99  99  SER SER B . n 
B 1 100 GLY 100 100 100 GLY GLY B . n 
B 1 101 ASN 101 101 101 ASN ASN B . n 
B 1 102 GLY 102 102 102 GLY GLY B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 PHE 105 105 105 PHE PHE B . n 
B 1 106 TRP 106 106 106 TRP TRP B . n 
B 1 107 ILE 107 107 107 ILE ILE B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 VAL 109 109 109 VAL VAL B . n 
B 1 110 PRO 110 110 110 PRO PRO B . n 
B 1 111 ARG 111 111 111 ARG ARG B . n 
B 1 112 GLU 112 112 112 GLU GLU B . n 
B 1 113 GLY 113 113 113 GLY GLY B . n 
B 1 114 GLY 114 114 114 GLY GLY B . n 
B 1 115 GLY 115 115 115 GLY GLY B . n 
B 1 116 GLY 116 116 116 GLY GLY B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 TRP 119 119 119 TRP TRP B . n 
B 1 120 THR 120 120 120 THR THR B . n 
B 1 121 ILE 121 121 121 ILE ILE B . n 
B 1 122 LYS 122 122 122 LYS LYS B . n 
B 1 123 PRO 123 123 123 PRO PRO B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 SER 125 125 ?   ?   ?   B . n 
B 1 126 SER 126 126 ?   ?   ?   B . n 
B 1 127 GLN 127 127 ?   ?   ?   B . n 
B 1 128 GLY 128 128 128 GLY GLY B . n 
B 1 129 PRO 129 129 129 PRO PRO B . n 
B 1 130 THR 130 130 130 THR THR B . n 
B 1 131 THR 131 131 131 THR THR B . n 
B 1 132 VAL 132 132 132 VAL VAL B . n 
B 1 133 PHE 133 133 133 PHE PHE B . n 
B 1 134 LEU 134 134 134 LEU LEU B . n 
B 1 135 ASP 135 135 135 ASP ASP B . n 
B 1 136 LEU 136 136 136 LEU LEU B . n 
B 1 137 LEU 137 137 137 LEU LEU B . n 
B 1 138 LYS 138 138 138 LYS LYS B . n 
B 1 139 GLU 139 139 139 GLU GLU B . n 
B 1 140 THR 140 140 140 THR THR B . n 
B 1 141 ASP 141 141 141 ASP ASP B . n 
B 1 142 PRO 142 142 142 PRO PRO B . n 
B 1 143 ASN 143 143 143 ASN ASN B . n 
B 1 144 GLN 144 144 144 GLN GLN B . n 
B 1 145 ARG 145 145 145 ARG ARG B . n 
B 1 146 ILE 146 146 146 ILE ILE B . n 
B 1 147 LYS 147 147 147 LYS LYS B . n 
B 1 148 PHE 148 148 148 PHE PHE B . n 
B 1 149 ALA 149 149 149 ALA ALA B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 ASP 151 151 ?   ?   ?   B . n 
B 1 152 PRO 152 152 ?   ?   ?   B . n 
B 1 153 ASN 153 153 ?   ?   ?   B . n 
B 1 154 SER 154 154 ?   ?   ?   B . n 
B 1 155 SER 155 155 ?   ?   ?   B . n 
B 1 156 VAL 156 156 ?   ?   ?   B . n 
B 1 157 ASP 157 157 ?   ?   ?   B . n 
B 1 158 LYS 158 158 ?   ?   ?   B . n 
B 1 159 LEU 159 159 ?   ?   ?   B . n 
B 1 160 ALA 160 160 ?   ?   ?   B . n 
B 1 161 ALA 161 161 ?   ?   ?   B . n 
B 1 162 ALA 162 162 ?   ?   ?   B . n 
B 1 163 LEU 163 163 ?   ?   ?   B . n 
B 1 164 GLU 164 164 ?   ?   ?   B . n 
B 1 165 HIS 165 165 ?   ?   ?   B . n 
B 1 166 HIS 166 166 ?   ?   ?   B . n 
B 1 167 HIS 167 167 ?   ?   ?   B . n 
B 1 168 HIS 168 168 ?   ?   ?   B . n 
B 1 169 HIS 169 169 ?   ?   ?   B . n 
B 1 170 HIS 170 170 ?   ?   ?   B . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 HOH 1  201 3  HOH HOH A . 
C 2 HOH 2  202 9  HOH HOH A . 
C 2 HOH 3  203 22 HOH HOH A . 
C 2 HOH 4  204 20 HOH HOH A . 
C 2 HOH 5  205 8  HOH HOH A . 
C 2 HOH 6  206 21 HOH HOH A . 
C 2 HOH 7  207 5  HOH HOH A . 
C 2 HOH 8  208 6  HOH HOH A . 
C 2 HOH 9  209 19 HOH HOH A . 
C 2 HOH 10 210 15 HOH HOH A . 
C 2 HOH 11 211 23 HOH HOH A . 
D 2 HOH 1  201 1  HOH HOH B . 
D 2 HOH 2  202 12 HOH HOH B . 
D 2 HOH 3  203 17 HOH HOH B . 
D 2 HOH 4  204 7  HOH HOH B . 
D 2 HOH 5  205 13 HOH HOH B . 
D 2 HOH 6  206 2  HOH HOH B . 
D 2 HOH 7  207 16 HOH HOH B . 
D 2 HOH 8  208 10 HOH HOH B . 
D 2 HOH 9  209 4  HOH HOH B . 
D 2 HOH 10 210 18 HOH HOH B . 
D 2 HOH 11 211 11 HOH HOH B . 
D 2 HOH 12 212 14 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_reference_DOI 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? REFMAC  ? ? ? 5.8.0258 ? 1 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .        ? 2 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .        ? 3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? MOLREP  ? ? ? .        ? 4 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   128.34 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9UDZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     102.692 
_cell.length_a_esd                 ? 
_cell.length_b                     44.121 
_cell.length_b_esd                 ? 
_cell.length_c                     77.503 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        8 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9UDZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                5 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'C 1 2 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9UDZ 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             1.84 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          33.12 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              8.2 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    'sodium phosphate monohydrate, potassium phosphate dibasic' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS PILATUS3 S 6M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-12-01 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.0 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'PHOTON FACTORY BEAMLINE BL-5A' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.0 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL-5A 
_diffrn_source.pdbx_synchrotron_site       'Photon Factory' 
# 
_reflns.B_iso_Wilson_estimate                          ? 
_reflns.entry_id                                       9UDZ 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.34 
_reflns.d_resolution_low                               40.31 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     11521 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.8 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.8 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          11.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               1.03 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                0.144 
_reflns.pdbx_Rpim_I_all                                0.054 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.133 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.34 
_reflns_shell.d_res_low                                     2.42 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           7729 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             1106 
_reflns_shell.percent_possible_obs                          97.7 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               7.0 
_reflns_shell.pdbx_chi_squared                              0.94 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     2.2 
_reflns_shell.pdbx_Rrim_I_all                               0.895 
_reflns_shell.pdbx_Rpim_I_all                               0.335 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.744 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.829 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            -0.04 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.03 
_refine.aniso_B[2][2]                            0.00 
_refine.aniso_B[2][3]                            -0.00 
_refine.aniso_B[3][3]                            -0.01 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               36.674 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               0.954 
_refine.correlation_coeff_Fo_to_Fc_free          0.904 
_refine.details                                  'HYDROGENS HAVE BEEN ADDED IN THE RIDING POSITIONS' 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9UDZ 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.34 
_refine.ls_d_res_low                             40.31 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     10951 
_refine.ls_number_reflns_R_free                  569 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.47 
_refine.ls_percent_reflns_R_free                 4.9 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.19088 
_refine.ls_R_factor_R_free                       0.25872 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.18724 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    MASK 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.correlation_coeff_I_to_Fcsqd_work        ? 
_refine.correlation_coeff_I_to_Fcsqd_free        ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      5EHA 
_refine.pdbx_stereochemistry_target_values       'MAXIMUM LIKELIHOOD' 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       0.449 
_refine.pdbx_overall_ESU_R_Free                  0.277 
_refine.pdbx_solvent_vdw_probe_radii             1.20 
_refine.pdbx_solvent_ion_probe_radii             0.80 
_refine.pdbx_solvent_shrinkage_radii             0.80 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             9.634 
_refine.overall_SU_ML                            0.222 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         1 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.34 
_refine_hist.d_res_low                        40.31 
_refine_hist.number_atoms_solvent             23 
_refine_hist.number_atoms_total               2192 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2169 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_Zscore 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.009  0.013  2221 ? r_bond_refined_d             ? ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.017  1969 ? r_bond_other_d               ? ? ? 
'X-RAY DIFFRACTION' ? 1.596  1.637  3018 ? r_angle_refined_deg          ? ? ? 
'X-RAY DIFFRACTION' ? 1.237  1.582  4575 ? r_angle_other_deg            ? ? ? 
'X-RAY DIFFRACTION' ? 8.658  5.000  272  ? r_dihedral_angle_1_deg       ? ? ? 
'X-RAY DIFFRACTION' ? 35.243 23.388 121  ? r_dihedral_angle_2_deg       ? ? ? 
'X-RAY DIFFRACTION' ? 18.607 15.000 343  ? r_dihedral_angle_3_deg       ? ? ? 
'X-RAY DIFFRACTION' ? 21.361 15.000 12   ? r_dihedral_angle_4_deg       ? ? ? 
'X-RAY DIFFRACTION' ? 0.058  0.200  286  ? r_chiral_restr               ? ? ? 
'X-RAY DIFFRACTION' ? 0.007  0.020  2514 ? r_gen_planes_refined         ? ? ? 
'X-RAY DIFFRACTION' ? 0.001  0.020  478  ? r_gen_planes_other           ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_refined                ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbd_other                  ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_refined              ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_nbtor_other                ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_refined        ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_xyhbond_nbd_other          ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_refined          ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_metal_ion_other            ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_refined       ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_vdw_other         ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_refined     ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_hbond_other       ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_refined ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_symmetry_metal_ion_other   ? ? ? 
'X-RAY DIFFRACTION' ? 3.161  3.795  1106 ? r_mcbond_it                  ? ? ? 
'X-RAY DIFFRACTION' ? 3.153  3.795  1105 ? r_mcbond_other               ? ? ? 
'X-RAY DIFFRACTION' ? 4.797  5.660  1372 ? r_mcangle_it                 ? ? ? 
'X-RAY DIFFRACTION' ? 4.797  5.661  1373 ? r_mcangle_other              ? ? ? 
'X-RAY DIFFRACTION' ? 3.354  4.084  1115 ? r_scbond_it                  ? ? ? 
'X-RAY DIFFRACTION' ? 3.353  4.084  1116 ? r_scbond_other               ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_scangle_it                 ? ? ? 
'X-RAY DIFFRACTION' ? 5.071  5.975  1647 ? r_scangle_other              ? ? ? 
'X-RAY DIFFRACTION' ? 7.103  41.644 2340 ? r_long_range_B_refined       ? ? ? 
'X-RAY DIFFRACTION' ? 7.102  41.656 2341 ? r_long_range_B_other         ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_rigid_bond_restr           ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_free            ? ? ? 
'X-RAY DIFFRACTION' ? ?      ?      ?    ? r_sphericity_bonded          ? ? ? 
# 
_refine_ls_shell.pdbx_refine_id                      'X-RAY DIFFRACTION' 
_refine_ls_shell.d_res_high                          2.340 
_refine_ls_shell.d_res_low                           2.401 
_refine_ls_shell.number_reflns_all                   ? 
_refine_ls_shell.number_reflns_obs                   ? 
_refine_ls_shell.number_reflns_R_free                37 
_refine_ls_shell.number_reflns_R_work                789 
_refine_ls_shell.percent_reflns_obs                  97.98 
_refine_ls_shell.percent_reflns_R_free               ? 
_refine_ls_shell.R_factor_all                        ? 
_refine_ls_shell.R_factor_obs                        ? 
_refine_ls_shell.R_factor_R_free_error               ? 
_refine_ls_shell.R_factor_R_work                     0.244 
_refine_ls_shell.redundancy_reflns_all               ? 
_refine_ls_shell.redundancy_reflns_obs               ? 
_refine_ls_shell.wR_factor_all                       ? 
_refine_ls_shell.wR_factor_obs                       ? 
_refine_ls_shell.wR_factor_R_free                    ? 
_refine_ls_shell.wR_factor_R_work                    ? 
_refine_ls_shell.pdbx_R_complete                     ? 
_refine_ls_shell.correlation_coeff_Fo_to_Fc          ? 
_refine_ls_shell.correlation_coeff_Fo_to_Fc_free     ? 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_work   ? 
_refine_ls_shell.correlation_coeff_I_to_Fcsqd_free   ? 
_refine_ls_shell.pdbx_total_number_of_bins_used      20 
_refine_ls_shell.pdbx_phase_error                    ? 
_refine_ls_shell.pdbx_fsc_work                       ? 
_refine_ls_shell.pdbx_fsc_free                       ? 
_refine_ls_shell.R_factor_R_free                     0.268 
# 
_struct.entry_id                     9UDZ 
_struct.title                        
'Crystal structure of recombinant mushroom Agaricus bisporus mannose-binding protein with a longer C-terminal region' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9UDZ 
_struct_keywords.text            'Lectin-like protein, Agaricus bisporus, SUGAR BINDING PROTEIN' 
_struct_keywords.pdbx_keywords   'SUGAR BINDING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    G1K3P4_AGABI 
_struct_ref.pdbx_db_accession          G1K3P4 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAQARKIPLDLPGTRILNGANWANNSATENLATNSGTLIIFDQSTPGQDADRWLIHNYLDGYKIFNMGSNNWASVSRGNT
VLGVSEFDGQTCKWSIEYSGNGEEFWIRVPREGGGGAVWTIKPASSQGPTTVFLDLLKETDPNQRIKFAV
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9UDZ A 1 ? 150 ? G1K3P4 1 ? 150 ? 1 150 
2 1 9UDZ B 1 ? 150 ? G1K3P4 1 ? 150 ? 1 150 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9UDZ ASP A 151 ? UNP G1K3P4 ? ? 'expression tag' 151 1  
1 9UDZ PRO A 152 ? UNP G1K3P4 ? ? 'expression tag' 152 2  
1 9UDZ ASN A 153 ? UNP G1K3P4 ? ? 'expression tag' 153 3  
1 9UDZ SER A 154 ? UNP G1K3P4 ? ? 'expression tag' 154 4  
1 9UDZ SER A 155 ? UNP G1K3P4 ? ? 'expression tag' 155 5  
1 9UDZ VAL A 156 ? UNP G1K3P4 ? ? 'expression tag' 156 6  
1 9UDZ ASP A 157 ? UNP G1K3P4 ? ? 'expression tag' 157 7  
1 9UDZ LYS A 158 ? UNP G1K3P4 ? ? 'expression tag' 158 8  
1 9UDZ LEU A 159 ? UNP G1K3P4 ? ? 'expression tag' 159 9  
1 9UDZ ALA A 160 ? UNP G1K3P4 ? ? 'expression tag' 160 10 
1 9UDZ ALA A 161 ? UNP G1K3P4 ? ? 'expression tag' 161 11 
1 9UDZ ALA A 162 ? UNP G1K3P4 ? ? 'expression tag' 162 12 
1 9UDZ LEU A 163 ? UNP G1K3P4 ? ? 'expression tag' 163 13 
1 9UDZ GLU A 164 ? UNP G1K3P4 ? ? 'expression tag' 164 14 
1 9UDZ HIS A 165 ? UNP G1K3P4 ? ? 'expression tag' 165 15 
1 9UDZ HIS A 166 ? UNP G1K3P4 ? ? 'expression tag' 166 16 
1 9UDZ HIS A 167 ? UNP G1K3P4 ? ? 'expression tag' 167 17 
1 9UDZ HIS A 168 ? UNP G1K3P4 ? ? 'expression tag' 168 18 
1 9UDZ HIS A 169 ? UNP G1K3P4 ? ? 'expression tag' 169 19 
1 9UDZ HIS A 170 ? UNP G1K3P4 ? ? 'expression tag' 170 20 
2 9UDZ ASP B 151 ? UNP G1K3P4 ? ? 'expression tag' 151 21 
2 9UDZ PRO B 152 ? UNP G1K3P4 ? ? 'expression tag' 152 22 
2 9UDZ ASN B 153 ? UNP G1K3P4 ? ? 'expression tag' 153 23 
2 9UDZ SER B 154 ? UNP G1K3P4 ? ? 'expression tag' 154 24 
2 9UDZ SER B 155 ? UNP G1K3P4 ? ? 'expression tag' 155 25 
2 9UDZ VAL B 156 ? UNP G1K3P4 ? ? 'expression tag' 156 26 
2 9UDZ ASP B 157 ? UNP G1K3P4 ? ? 'expression tag' 157 27 
2 9UDZ LYS B 158 ? UNP G1K3P4 ? ? 'expression tag' 158 28 
2 9UDZ LEU B 159 ? UNP G1K3P4 ? ? 'expression tag' 159 29 
2 9UDZ ALA B 160 ? UNP G1K3P4 ? ? 'expression tag' 160 30 
2 9UDZ ALA B 161 ? UNP G1K3P4 ? ? 'expression tag' 161 31 
2 9UDZ ALA B 162 ? UNP G1K3P4 ? ? 'expression tag' 162 32 
2 9UDZ LEU B 163 ? UNP G1K3P4 ? ? 'expression tag' 163 33 
2 9UDZ GLU B 164 ? UNP G1K3P4 ? ? 'expression tag' 164 34 
2 9UDZ HIS B 165 ? UNP G1K3P4 ? ? 'expression tag' 165 35 
2 9UDZ HIS B 166 ? UNP G1K3P4 ? ? 'expression tag' 166 36 
2 9UDZ HIS B 167 ? UNP G1K3P4 ? ? 'expression tag' 167 37 
2 9UDZ HIS B 168 ? UNP G1K3P4 ? ? 'expression tag' 168 38 
2 9UDZ HIS B 169 ? UNP G1K3P4 ? ? 'expression tag' 169 39 
2 9UDZ HIS B 170 ? UNP G1K3P4 ? ? 'expression tag' 170 40 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? monomeric 1 
2 author_defined_assembly ? monomeric 1 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C 
2 1 B,D 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 ARG A 77  ? ASN A 79  ? ARG A 77  ASN A 79  5 ? 3 
HELX_P HELX_P2 AA2 ASP A 141 ? ARG A 145 ? ASP A 141 ARG A 145 5 ? 5 
HELX_P HELX_P3 AA3 ARG B 77  ? ASN B 79  ? ARG B 77  ASN B 79  5 ? 3 
HELX_P HELX_P4 AA4 ASP B 88  ? LYS B 93  ? ASP B 88  LYS B 93  1 ? 6 
HELX_P HELX_P5 AA5 ASP B 141 ? ARG B 145 ? ASP B 141 ARG B 145 5 ? 5 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 4 ? 
AA7 ? 5 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA7 4 5 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 40  ? ASP A 42  ? ILE A 40  ASP A 42  
AA1 2 ASN A 21  ? ASN A 24  ? ASN A 21  ASN A 24  
AA1 3 THR A 14  ? ASN A 18  ? THR A 14  ASN A 18  
AA1 4 LYS A 147 ? VAL A 150 ? LYS A 147 VAL A 150 
AA2 1 THR A 37  ? LEU A 38  ? THR A 37  LEU A 38  
AA2 2 VAL A 81  ? VAL A 84  ? VAL A 81  VAL A 84  
AA2 3 TRP A 72  ? VAL A 75  ? TRP A 72  VAL A 75  
AA3 1 TRP A 53  ? TYR A 58  ? TRP A 53  TYR A 58  
AA3 2 GLY A 61  ? ASN A 66  ? GLY A 61  ASN A 66  
AA4 1 SER A 95  ? TYR A 98  ? SER A 95  TYR A 98  
AA4 2 PHE A 105 ? ARG A 108 ? PHE A 105 ARG A 108 
AA5 1 VAL A 118 ? ILE A 121 ? VAL A 118 ILE A 121 
AA5 2 VAL A 132 ? ASP A 135 ? VAL A 132 ASP A 135 
AA6 1 ILE B 40  ? ASP B 42  ? ILE B 40  ASP B 42  
AA6 2 ASN B 21  ? ASN B 24  ? ASN B 21  ASN B 24  
AA6 3 ARG B 15  ? ASN B 18  ? ARG B 15  ASN B 18  
AA6 4 LYS B 147 ? ALA B 149 ? LYS B 147 ALA B 149 
AA7 1 THR B 37  ? LEU B 38  ? THR B 37  LEU B 38  
AA7 2 VAL B 81  ? VAL B 84  ? VAL B 81  VAL B 84  
AA7 3 ASN B 71  ? VAL B 75  ? ASN B 71  VAL B 75  
AA7 4 GLY B 61  ? ASN B 66  ? GLY B 61  ASN B 66  
AA7 5 TRP B 53  ? TYR B 58  ? TRP B 53  TYR B 58  
AA8 1 SER B 95  ? TYR B 98  ? SER B 95  TYR B 98  
AA8 2 PHE B 105 ? ARG B 108 ? PHE B 105 ARG B 108 
AA9 1 VAL B 118 ? ILE B 121 ? VAL B 118 ILE B 121 
AA9 2 VAL B 132 ? ASP B 135 ? VAL B 132 ASP B 135 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O ILE A 40  ? O ILE A 40  N ASN A 24  ? N ASN A 24  
AA1 2 3 O ASN A 21  ? O ASN A 21  N ASN A 18  ? N ASN A 18  
AA1 3 4 N LEU A 17  ? N LEU A 17  O LYS A 147 ? O LYS A 147 
AA2 1 2 N THR A 37  ? N THR A 37  O GLY A 83  ? O GLY A 83  
AA2 2 3 O VAL A 84  ? O VAL A 84  N TRP A 72  ? N TRP A 72  
AA3 1 2 N LEU A 54  ? N LEU A 54  O PHE A 65  ? O PHE A 65  
AA4 1 2 N SER A 95  ? N SER A 95  O ARG A 108 ? O ARG A 108 
AA5 1 2 N VAL A 118 ? N VAL A 118 O ASP A 135 ? O ASP A 135 
AA6 1 2 O ILE B 40  ? O ILE B 40  N ASN B 24  ? N ASN B 24  
AA6 2 3 O ALA B 23  ? O ALA B 23  N ILE B 16  ? N ILE B 16  
AA6 3 4 N LEU B 17  ? N LEU B 17  O LYS B 147 ? O LYS B 147 
AA7 1 2 N THR B 37  ? N THR B 37  O GLY B 83  ? O GLY B 83  
AA7 2 3 O VAL B 84  ? O VAL B 84  N TRP B 72  ? N TRP B 72  
AA7 3 4 O ALA B 73  ? O ALA B 73  N ILE B 64  ? N ILE B 64  
AA7 4 5 O GLY B 61  ? O GLY B 61  N TYR B 58  ? N TYR B 58  
AA8 1 2 N GLU B 97  ? N GLU B 97  O TRP B 106 ? O TRP B 106 
AA9 1 2 N THR B 120 ? N THR B 120 O PHE B 133 ? O PHE B 133 
# 
_pdbx_entry_details.entry_id                   9UDZ 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 59 ? ? 45.97   -123.57 
2 1 SER A 76 ? ? -126.90 -166.98 
3 1 LEU B 59 ? ? 53.06   -120.01 
4 1 SER B 76 ? ? -126.03 -159.53 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ALA 2   ? A ALA 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ALA 4   ? A ALA 4   
5  1 Y 1 A ARG 5   ? A ARG 5   
6  1 Y 1 A LEU 31  ? A LEU 31  
7  1 Y 1 A ALA 32  ? A ALA 32  
8  1 Y 1 A THR 33  ? A THR 33  
9  1 Y 1 A ALA 124 ? A ALA 124 
10 1 Y 1 A SER 125 ? A SER 125 
11 1 Y 1 A SER 126 ? A SER 126 
12 1 Y 1 A GLN 127 ? A GLN 127 
13 1 Y 1 A PRO 152 ? A PRO 152 
14 1 Y 1 A ASN 153 ? A ASN 153 
15 1 Y 1 A SER 154 ? A SER 154 
16 1 Y 1 A SER 155 ? A SER 155 
17 1 Y 1 A VAL 156 ? A VAL 156 
18 1 Y 1 A ASP 157 ? A ASP 157 
19 1 Y 1 A LYS 158 ? A LYS 158 
20 1 Y 1 A LEU 159 ? A LEU 159 
21 1 Y 1 A ALA 160 ? A ALA 160 
22 1 Y 1 A ALA 161 ? A ALA 161 
23 1 Y 1 A ALA 162 ? A ALA 162 
24 1 Y 1 A LEU 163 ? A LEU 163 
25 1 Y 1 A GLU 164 ? A GLU 164 
26 1 Y 1 A HIS 165 ? A HIS 165 
27 1 Y 1 A HIS 166 ? A HIS 166 
28 1 Y 1 A HIS 167 ? A HIS 167 
29 1 Y 1 A HIS 168 ? A HIS 168 
30 1 Y 1 A HIS 169 ? A HIS 169 
31 1 Y 1 A HIS 170 ? A HIS 170 
32 1 Y 1 B MET 1   ? B MET 1   
33 1 Y 1 B ALA 2   ? B ALA 2   
34 1 Y 1 B GLN 3   ? B GLN 3   
35 1 Y 1 B ALA 4   ? B ALA 4   
36 1 Y 1 B ARG 5   ? B ARG 5   
37 1 Y 1 B LEU 31  ? B LEU 31  
38 1 Y 1 B ALA 32  ? B ALA 32  
39 1 Y 1 B THR 33  ? B THR 33  
40 1 Y 1 B SER 125 ? B SER 125 
41 1 Y 1 B SER 126 ? B SER 126 
42 1 Y 1 B GLN 127 ? B GLN 127 
43 1 Y 1 B ASP 151 ? B ASP 151 
44 1 Y 1 B PRO 152 ? B PRO 152 
45 1 Y 1 B ASN 153 ? B ASN 153 
46 1 Y 1 B SER 154 ? B SER 154 
47 1 Y 1 B SER 155 ? B SER 155 
48 1 Y 1 B VAL 156 ? B VAL 156 
49 1 Y 1 B ASP 157 ? B ASP 157 
50 1 Y 1 B LYS 158 ? B LYS 158 
51 1 Y 1 B LEU 159 ? B LEU 159 
52 1 Y 1 B ALA 160 ? B ALA 160 
53 1 Y 1 B ALA 161 ? B ALA 161 
54 1 Y 1 B ALA 162 ? B ALA 162 
55 1 Y 1 B LEU 163 ? B LEU 163 
56 1 Y 1 B GLU 164 ? B GLU 164 
57 1 Y 1 B HIS 165 ? B HIS 165 
58 1 Y 1 B HIS 166 ? B HIS 166 
59 1 Y 1 B HIS 167 ? B HIS 167 
60 1 Y 1 B HIS 168 ? B HIS 168 
61 1 Y 1 B HIS 169 ? B HIS 169 
62 1 Y 1 B HIS 170 ? B HIS 170 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
_pdbx_audit_support.funding_organization   'Not funded' 
_pdbx_audit_support.country                Japan 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5EHA 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9UDZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009738 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.007700 
_atom_sites.fract_transf_matrix[2][1]   -0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.022665 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   -0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.016449 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LYS A 1 6   ? -20.839 -11.807 -21.751 1.00 56.31 ? 6   LYS A N   1 
ATOM   2    C CA  . LYS A 1 6   ? -20.393 -11.329 -23.085 1.00 58.31 ? 6   LYS A CA  1 
ATOM   3    C C   . LYS A 1 6   ? -18.932 -11.727 -23.284 1.00 55.05 ? 6   LYS A C   1 
ATOM   4    O O   . LYS A 1 6   ? -18.227 -11.980 -22.283 1.00 51.98 ? 6   LYS A O   1 
ATOM   5    C CB  . LYS A 1 6   ? -20.542 -9.812  -23.225 1.00 59.92 ? 6   LYS A CB  1 
ATOM   6    C CG  . LYS A 1 6   ? -21.325 -9.348  -24.444 1.00 62.45 ? 6   LYS A CG  1 
ATOM   7    C CD  . LYS A 1 6   ? -21.974 -7.982  -24.247 1.00 69.85 ? 6   LYS A CD  1 
ATOM   8    C CE  . LYS A 1 6   ? -21.054 -6.814  -24.555 1.00 70.06 ? 6   LYS A CE  1 
ATOM   9    N NZ  . LYS A 1 6   ? -21.129 -6.427  -25.986 1.00 67.51 ? 6   LYS A NZ  1 
ATOM   10   N N   . ILE A 1 7   ? -18.504 -11.788 -24.540 1.00 49.69 ? 7   ILE A N   1 
ATOM   11   C CA  . ILE A 1 7   ? -17.135 -12.257 -24.911 1.00 48.94 ? 7   ILE A CA  1 
ATOM   12   C C   . ILE A 1 7   ? -16.158 -11.153 -24.518 1.00 40.93 ? 7   ILE A C   1 
ATOM   13   O O   . ILE A 1 7   ? -16.365 -10.005 -24.885 1.00 40.21 ? 7   ILE A O   1 
ATOM   14   C CB  . ILE A 1 7   ? -17.082 -12.638 -26.413 1.00 48.62 ? 7   ILE A CB  1 
ATOM   15   C CG1 . ILE A 1 7   ? -18.095 -13.745 -26.743 1.00 48.57 ? 7   ILE A CG1 1 
ATOM   16   C CG2 . ILE A 1 7   ? -15.671 -13.019 -26.854 1.00 44.28 ? 7   ILE A CG2 1 
ATOM   17   C CD1 . ILE A 1 7   ? -18.446 -13.847 -28.210 1.00 50.50 ? 7   ILE A CD1 1 
ATOM   18   N N   . PRO A 1 8   ? -15.099 -11.444 -23.728 1.00 38.93 ? 8   PRO A N   1 
ATOM   19   C CA  . PRO A 1 8   ? -14.077 -10.443 -23.422 1.00 36.28 ? 8   PRO A CA  1 
ATOM   20   C C   . PRO A 1 8   ? -13.185 -10.190 -24.650 1.00 37.68 ? 8   PRO A C   1 
ATOM   21   O O   . PRO A 1 8   ? -12.182 -10.859 -24.859 1.00 42.89 ? 8   PRO A O   1 
ATOM   22   C CB  . PRO A 1 8   ? -13.320 -11.062 -22.246 1.00 35.12 ? 8   PRO A CB  1 
ATOM   23   C CG  . PRO A 1 8   ? -13.434 -12.553 -22.494 1.00 38.63 ? 8   PRO A CG  1 
ATOM   24   C CD  . PRO A 1 8   ? -14.822 -12.741 -23.087 1.00 39.25 ? 8   PRO A CD  1 
ATOM   25   N N   . LEU A 1 9   ? -13.607 -9.244  -25.475 1.00 37.93 ? 9   LEU A N   1 
ATOM   26   C CA  . LEU A 1 9   ? -12.865 -8.804  -26.675 1.00 36.18 ? 9   LEU A CA  1 
ATOM   27   C C   . LEU A 1 9   ? -11.782 -7.842  -26.234 1.00 34.46 ? 9   LEU A C   1 
ATOM   28   O O   . LEU A 1 9   ? -11.995 -7.119  -25.261 1.00 33.71 ? 9   LEU A O   1 
ATOM   29   C CB  . LEU A 1 9   ? -13.815 -8.147  -27.670 1.00 36.66 ? 9   LEU A CB  1 
ATOM   30   C CG  . LEU A 1 9   ? -14.805 -9.108  -28.316 1.00 38.86 ? 9   LEU A CG  1 
ATOM   31   C CD1 . LEU A 1 9   ? -15.742 -8.335  -29.217 1.00 42.02 ? 9   LEU A CD1 1 
ATOM   32   C CD2 . LEU A 1 9   ? -14.066 -10.180 -29.092 1.00 37.73 ? 9   LEU A CD2 1 
ATOM   33   N N   . ASP A 1 10  ? -10.631 -7.956  -26.881 1.00 33.97 ? 10  ASP A N   1 
ATOM   34   C CA  . ASP A 1 10  ? -9.510  -6.991  -26.767 1.00 33.77 ? 10  ASP A CA  1 
ATOM   35   C C   . ASP A 1 10  ? -9.031  -6.914  -25.322 1.00 29.62 ? 10  ASP A C   1 
ATOM   36   O O   . ASP A 1 10  ? -8.564  -5.827  -24.935 1.00 28.70 ? 10  ASP A O   1 
ATOM   37   C CB  . ASP A 1 10  ? -9.959  -5.639  -27.332 1.00 34.38 ? 10  ASP A CB  1 
ATOM   38   C CG  . ASP A 1 10  ? -10.555 -5.705  -28.735 1.00 32.48 ? 10  ASP A CG  1 
ATOM   39   O OD1 . ASP A 1 10  ? -10.330 -6.729  -29.484 1.00 28.01 ? 10  ASP A OD1 1 
ATOM   40   O OD2 . ASP A 1 10  ? -11.221 -4.725  -29.093 1.00 37.77 ? 10  ASP A OD2 1 
ATOM   41   N N   . LEU A 1 11  ? -9.076  -8.029  -24.585 1.00 29.66 ? 11  LEU A N   1 
ATOM   42   C CA  . LEU A 1 11  ? -8.563  -8.126  -23.180 1.00 30.36 ? 11  LEU A CA  1 
ATOM   43   C C   . LEU A 1 11  ? -7.428  -9.141  -23.037 1.00 29.16 ? 11  LEU A C   1 
ATOM   44   O O   . LEU A 1 11  ? -7.659  -10.336 -22.865 1.00 29.37 ? 11  LEU A O   1 
ATOM   45   C CB  . LEU A 1 11  ? -9.736  -8.440  -22.247 1.00 29.97 ? 11  LEU A CB  1 
ATOM   46   C CG  . LEU A 1 11  ? -10.655 -7.238  -22.044 1.00 33.19 ? 11  LEU A CG  1 
ATOM   47   C CD1 . LEU A 1 11  ? -12.015 -7.624  -21.477 1.00 33.13 ? 11  LEU A CD1 1 
ATOM   48   C CD2 . LEU A 1 11  ? -9.963  -6.220  -21.163 1.00 36.48 ? 11  LEU A CD2 1 
ATOM   49   N N   . PRO A 1 12  ? -6.166  -8.660  -23.066 1.00 33.15 ? 12  PRO A N   1 
ATOM   50   C CA  . PRO A 1 12  ? -4.962  -9.491  -22.937 1.00 35.02 ? 12  PRO A CA  1 
ATOM   51   C C   . PRO A 1 12  ? -4.879  -10.537 -21.817 1.00 36.77 ? 12  PRO A C   1 
ATOM   52   O O   . PRO A 1 12  ? -4.203  -11.516 -21.942 1.00 39.16 ? 12  PRO A O   1 
ATOM   53   C CB  . PRO A 1 12  ? -3.911  -8.431  -22.573 1.00 36.91 ? 12  PRO A CB  1 
ATOM   54   C CG  . PRO A 1 12  ? -4.326  -7.200  -23.312 1.00 36.36 ? 12  PRO A CG  1 
ATOM   55   C CD  . PRO A 1 12  ? -5.836  -7.253  -23.337 1.00 35.98 ? 12  PRO A CD  1 
ATOM   56   N N   . GLY A 1 13  ? -5.526  -10.301 -20.692 1.00 43.44 ? 13  GLY A N   1 
ATOM   57   C CA  . GLY A 1 13  ? -5.394  -11.236 -19.559 1.00 43.78 ? 13  GLY A CA  1 
ATOM   58   C C   . GLY A 1 13  ? -6.331  -12.431 -19.641 1.00 42.67 ? 13  GLY A C   1 
ATOM   59   O O   . GLY A 1 13  ? -6.525  -13.093 -18.585 1.00 46.07 ? 13  GLY A O   1 
ATOM   60   N N   . THR A 1 14  ? -6.957  -12.701 -20.793 1.00 40.99 ? 14  THR A N   1 
ATOM   61   C CA  . THR A 1 14  ? -8.078  -13.682 -20.853 1.00 36.97 ? 14  THR A CA  1 
ATOM   62   C C   . THR A 1 14  ? -7.497  -15.093 -20.715 1.00 35.17 ? 14  THR A C   1 
ATOM   63   O O   . THR A 1 14  ? -6.578  -15.427 -21.475 1.00 33.89 ? 14  THR A O   1 
ATOM   64   C CB  . THR A 1 14  ? -8.957  -13.526 -22.100 1.00 35.59 ? 14  THR A CB  1 
ATOM   65   O OG1 . THR A 1 14  ? -9.571  -12.237 -22.102 1.00 34.11 ? 14  THR A OG1 1 
ATOM   66   C CG2 . THR A 1 14  ? -10.046 -14.573 -22.157 1.00 34.29 ? 14  THR A CG2 1 
ATOM   67   N N   . ARG A 1 15  ? -7.988  -15.847 -19.731 1.00 33.96 ? 15  ARG A N   1 
ATOM   68   C CA  . ARG A 1 15  ? -7.829  -17.314 -19.633 1.00 34.39 ? 15  ARG A CA  1 
ATOM   69   C C   . ARG A 1 15  ? -9.037  -17.992 -20.281 1.00 30.62 ? 15  ARG A C   1 
ATOM   70   O O   . ARG A 1 15  ? -10.176 -17.472 -20.124 1.00 27.02 ? 15  ARG A O   1 
ATOM   71   C CB  . ARG A 1 15  ? -7.689  -17.725 -18.165 1.00 40.61 ? 15  ARG A CB  1 
ATOM   72   C CG  . ARG A 1 15  ? -6.274  -17.562 -17.642 1.00 47.94 ? 15  ARG A CG  1 
ATOM   73   C CD  . ARG A 1 15  ? -6.230  -17.091 -16.217 1.00 55.76 ? 15  ARG A CD  1 
ATOM   74   N NE  . ARG A 1 15  ? -5.129  -17.786 -15.572 1.00 64.41 ? 15  ARG A NE  1 
ATOM   75   C CZ  . ARG A 1 15  ? -5.253  -18.882 -14.833 1.00 64.04 ? 15  ARG A CZ  1 
ATOM   76   N NH1 . ARG A 1 15  ? -6.445  -19.415 -14.611 1.00 66.51 ? 15  ARG A NH1 1 
ATOM   77   N NH2 . ARG A 1 15  ? -4.179  -19.423 -14.286 1.00 63.06 ? 15  ARG A NH2 1 
ATOM   78   N N   . ILE A 1 16  ? -8.811  -19.148 -20.914 1.00 28.70 ? 16  ILE A N   1 
ATOM   79   C CA  . ILE A 1 16  ? -9.872  -19.970 -21.562 1.00 28.78 ? 16  ILE A CA  1 
ATOM   80   C C   . ILE A 1 16  ? -10.096 -21.211 -20.694 1.00 28.36 ? 16  ILE A C   1 
ATOM   81   O O   . ILE A 1 16  ? -9.191  -22.018 -20.587 1.00 30.62 ? 16  ILE A O   1 
ATOM   82   C CB  . ILE A 1 16  ? -9.494  -20.297 -23.026 1.00 27.45 ? 16  ILE A CB  1 
ATOM   83   C CG1 . ILE A 1 16  ? -9.432  -19.027 -23.888 1.00 27.00 ? 16  ILE A CG1 1 
ATOM   84   C CG2 . ILE A 1 16  ? -10.484 -21.309 -23.572 1.00 30.11 ? 16  ILE A CG2 1 
ATOM   85   C CD1 . ILE A 1 16  ? -8.826  -19.198 -25.280 1.00 26.50 ? 16  ILE A CD1 1 
ATOM   86   N N   . LEU A 1 17  ? -11.279 -21.349 -20.105 1.00 30.12 ? 17  LEU A N   1 
ATOM   87   C CA  . LEU A 1 17  ? -11.558 -22.304 -18.994 1.00 32.99 ? 17  LEU A CA  1 
ATOM   88   C C   . LEU A 1 17  ? -12.399 -23.493 -19.474 1.00 33.41 ? 17  LEU A C   1 
ATOM   89   O O   . LEU A 1 17  ? -13.343 -23.298 -20.309 1.00 36.36 ? 17  LEU A O   1 
ATOM   90   C CB  . LEU A 1 17  ? -12.325 -21.538 -17.912 1.00 33.66 ? 17  LEU A CB  1 
ATOM   91   C CG  . LEU A 1 17  ? -11.520 -21.108 -16.707 1.00 36.55 ? 17  LEU A CG  1 
ATOM   92   C CD1 . LEU A 1 17  ? -10.182 -20.505 -17.124 1.00 37.81 ? 17  LEU A CD1 1 
ATOM   93   C CD2 . LEU A 1 17  ? -12.328 -20.143 -15.846 1.00 35.50 ? 17  LEU A CD2 1 
ATOM   94   N N   . ASN A 1 18  ? -12.102 -24.678 -18.956 1.00 30.07 ? 18  ASN A N   1 
ATOM   95   C CA  . ASN A 1 18  ? -13.040 -25.824 -19.020 1.00 32.19 ? 18  ASN A CA  1 
ATOM   96   C C   . ASN A 1 18  ? -12.975 -26.535 -17.676 1.00 31.94 ? 18  ASN A C   1 
ATOM   97   O O   . ASN A 1 18  ? -11.866 -26.962 -17.292 1.00 35.37 ? 18  ASN A O   1 
ATOM   98   C CB  . ASN A 1 18  ? -12.760 -26.770 -20.183 1.00 31.28 ? 18  ASN A CB  1 
ATOM   99   C CG  . ASN A 1 18  ? -13.718 -27.942 -20.204 1.00 35.84 ? 18  ASN A CG  1 
ATOM   100  O OD1 . ASN A 1 18  ? -13.330 -29.059 -19.866 1.00 36.86 ? 18  ASN A OD1 1 
ATOM   101  N ND2 . ASN A 1 18  ? -14.965 -27.709 -20.599 1.00 33.39 ? 18  ASN A ND2 1 
ATOM   102  N N   . GLY A 1 19  ? -14.097 -26.572 -16.959 1.00 33.94 ? 19  GLY A N   1 
ATOM   103  C CA  . GLY A 1 19  ? -14.148 -27.071 -15.574 1.00 33.76 ? 19  GLY A CA  1 
ATOM   104  C C   . GLY A 1 19  ? -13.067 -26.375 -14.780 1.00 33.48 ? 19  GLY A C   1 
ATOM   105  O O   . GLY A 1 19  ? -13.038 -25.145 -14.816 1.00 35.37 ? 19  GLY A O   1 
ATOM   106  N N   . ALA A 1 20  ? -12.137 -27.127 -14.209 1.00 33.49 ? 20  ALA A N   1 
ATOM   107  C CA  . ALA A 1 20  ? -11.024 -26.594 -13.391 1.00 32.92 ? 20  ALA A CA  1 
ATOM   108  C C   . ALA A 1 20  ? -9.768  -26.377 -14.254 1.00 31.50 ? 20  ALA A C   1 
ATOM   109  O O   . ALA A 1 20  ? -8.798  -25.793 -13.759 1.00 32.45 ? 20  ALA A O   1 
ATOM   110  C CB  . ALA A 1 20  ? -10.771 -27.537 -12.244 1.00 33.05 ? 20  ALA A CB  1 
ATOM   111  N N   . ASN A 1 21  ? -9.773  -26.814 -15.512 1.00 31.77 ? 21  ASN A N   1 
ATOM   112  C CA  . ASN A 1 21  ? -8.580  -26.698 -16.396 1.00 30.10 ? 21  ASN A CA  1 
ATOM   113  C C   . ASN A 1 21  ? -8.642  -25.363 -17.124 1.00 28.96 ? 21  ASN A C   1 
ATOM   114  O O   . ASN A 1 21  ? -9.739  -24.740 -17.147 1.00 29.17 ? 21  ASN A O   1 
ATOM   115  C CB  . ASN A 1 21  ? -8.463  -27.894 -17.335 1.00 29.88 ? 21  ASN A CB  1 
ATOM   116  C CG  . ASN A 1 21  ? -8.159  -29.129 -16.528 1.00 28.40 ? 21  ASN A CG  1 
ATOM   117  O OD1 . ASN A 1 21  ? -7.364  -29.071 -15.611 1.00 34.90 ? 21  ASN A OD1 1 
ATOM   118  N ND2 . ASN A 1 21  ? -8.832  -30.218 -16.799 1.00 33.37 ? 21  ASN A ND2 1 
ATOM   119  N N   . TRP A 1 22  ? -7.496  -24.907 -17.623 1.00 26.00 ? 22  TRP A N   1 
ATOM   120  C CA  . TRP A 1 22  ? -7.448  -23.714 -18.498 1.00 25.94 ? 22  TRP A CA  1 
ATOM   121  C C   . TRP A 1 22  ? -6.513  -24.022 -19.677 1.00 24.14 ? 22  TRP A C   1 
ATOM   122  O O   . TRP A 1 22  ? -5.650  -24.865 -19.524 1.00 26.58 ? 22  TRP A O   1 
ATOM   123  C CB  . TRP A 1 22  ? -7.087  -22.465 -17.674 1.00 27.13 ? 22  TRP A CB  1 
ATOM   124  C CG  . TRP A 1 22  ? -5.725  -22.504 -17.057 1.00 29.51 ? 22  TRP A CG  1 
ATOM   125  C CD1 . TRP A 1 22  ? -4.536  -22.305 -17.693 1.00 30.87 ? 22  TRP A CD1 1 
ATOM   126  C CD2 . TRP A 1 22  ? -5.409  -22.849 -15.700 1.00 29.26 ? 22  TRP A CD2 1 
ATOM   127  N NE1 . TRP A 1 22  ? -3.502  -22.495 -16.818 1.00 34.41 ? 22  TRP A NE1 1 
ATOM   128  C CE2 . TRP A 1 22  ? -4.009  -22.819 -15.585 1.00 32.50 ? 22  TRP A CE2 1 
ATOM   129  C CE3 . TRP A 1 22  ? -6.169  -23.172 -14.571 1.00 31.82 ? 22  TRP A CE3 1 
ATOM   130  C CZ2 . TRP A 1 22  ? -3.359  -23.063 -14.376 1.00 32.38 ? 22  TRP A CZ2 1 
ATOM   131  C CZ3 . TRP A 1 22  ? -5.528  -23.410 -13.377 1.00 32.90 ? 22  TRP A CZ3 1 
ATOM   132  C CH2 . TRP A 1 22  ? -4.139  -23.377 -13.288 1.00 32.61 ? 22  TRP A CH2 1 
ATOM   133  N N   . ALA A 1 23  ? -6.705  -23.378 -20.817 1.00 23.92 ? 23  ALA A N   1 
ATOM   134  C CA  . ALA A 1 23  ? -5.976  -23.654 -22.072 1.00 26.21 ? 23  ALA A CA  1 
ATOM   135  C C   . ALA A 1 23  ? -4.562  -23.039 -21.998 1.00 27.07 ? 23  ALA A C   1 
ATOM   136  O O   . ALA A 1 23  ? -4.407  -21.868 -21.563 1.00 24.57 ? 23  ALA A O   1 
ATOM   137  C CB  . ALA A 1 23  ? -6.771  -23.115 -23.239 1.00 26.20 ? 23  ALA A CB  1 
ATOM   138  N N   . ASN A 1 24  ? -3.562  -23.827 -22.394 1.00 28.37 ? 24  ASN A N   1 
ATOM   139  C CA  . ASN A 1 24  ? -2.126  -23.449 -22.457 1.00 31.00 ? 24  ASN A CA  1 
ATOM   140  C C   . ASN A 1 24  ? -1.629  -23.713 -23.877 1.00 28.78 ? 24  ASN A C   1 
ATOM   141  O O   . ASN A 1 24  ? -2.210  -24.556 -24.579 1.00 28.38 ? 24  ASN A O   1 
ATOM   142  C CB  . ASN A 1 24  ? -1.278  -24.214 -21.439 1.00 34.16 ? 24  ASN A CB  1 
ATOM   143  C CG  . ASN A 1 24  ? -1.791  -24.035 -20.026 1.00 38.53 ? 24  ASN A CG  1 
ATOM   144  O OD1 . ASN A 1 24  ? -1.731  -22.924 -19.477 1.00 35.43 ? 24  ASN A OD1 1 
ATOM   145  N ND2 . ASN A 1 24  ? -2.341  -25.101 -19.449 1.00 41.91 ? 24  ASN A ND2 1 
ATOM   146  N N   . ASN A 1 25  ? -0.604  -22.990 -24.294 1.00 26.64 ? 25  ASN A N   1 
ATOM   147  C CA  . ASN A 1 25  ? 0.026   -23.220 -25.611 1.00 27.87 ? 25  ASN A CA  1 
ATOM   148  C C   . ASN A 1 25  ? 1.422   -22.619 -25.550 1.00 29.48 ? 25  ASN A C   1 
ATOM   149  O O   . ASN A 1 25  ? 1.511   -21.506 -25.027 1.00 31.96 ? 25  ASN A O   1 
ATOM   150  C CB  . ASN A 1 25  ? -0.801  -22.629 -26.755 1.00 26.58 ? 25  ASN A CB  1 
ATOM   151  C CG  . ASN A 1 25  ? -0.147  -22.902 -28.085 1.00 26.41 ? 25  ASN A CG  1 
ATOM   152  O OD1 . ASN A 1 25  ? 0.464   -21.996 -28.673 1.00 27.30 ? 25  ASN A OD1 1 
ATOM   153  N ND2 . ASN A 1 25  ? -0.187  -24.153 -28.503 1.00 21.92 ? 25  ASN A ND2 1 
ATOM   154  N N   . SER A 1 26  ? 2.426   -23.327 -26.082 1.00 30.52 ? 26  SER A N   1 
ATOM   155  C CA  . SER A 1 26  ? 3.851   -22.916 -26.126 1.00 32.14 ? 26  SER A CA  1 
ATOM   156  C C   . SER A 1 26  ? 4.238   -22.471 -27.531 1.00 32.13 ? 26  SER A C   1 
ATOM   157  O O   . SER A 1 26  ? 3.689   -23.016 -28.513 1.00 33.07 ? 26  SER A O   1 
ATOM   158  C CB  . SER A 1 26  ? 4.744   -24.040 -25.710 1.00 35.18 ? 26  SER A CB  1 
ATOM   159  O OG  . SER A 1 26  ? 4.414   -24.458 -24.406 1.00 40.49 ? 26  SER A OG  1 
ATOM   160  N N   . ALA A 1 27  ? 5.209   -21.567 -27.587 1.00 32.07 ? 27  ALA A N   1 
ATOM   161  C CA  . ALA A 1 27  ? 5.893   -21.088 -28.805 1.00 35.42 ? 27  ALA A CA  1 
ATOM   162  C C   . ALA A 1 27  ? 6.463   -22.293 -29.545 1.00 38.56 ? 27  ALA A C   1 
ATOM   163  O O   . ALA A 1 27  ? 6.978   -23.208 -28.882 1.00 33.79 ? 27  ALA A O   1 
ATOM   164  C CB  . ALA A 1 27  ? 7.009   -20.108 -28.461 1.00 34.09 ? 27  ALA A CB  1 
ATOM   165  N N   . THR A 1 28  ? 6.392   -22.237 -30.865 1.00 40.81 ? 28  THR A N   1 
ATOM   166  C CA  . THR A 1 28  ? 7.019   -23.199 -31.790 1.00 50.34 ? 28  THR A CA  1 
ATOM   167  C C   . THR A 1 28  ? 8.532   -22.948 -31.824 1.00 59.54 ? 28  THR A C   1 
ATOM   168  O O   . THR A 1 28  ? 8.927   -21.804 -32.153 1.00 58.74 ? 28  THR A O   1 
ATOM   169  C CB  . THR A 1 28  ? 6.372   -23.078 -33.170 1.00 50.43 ? 28  THR A CB  1 
ATOM   170  O OG1 . THR A 1 28  ? 6.791   -24.244 -33.872 1.00 64.17 ? 28  THR A OG1 1 
ATOM   171  C CG2 . THR A 1 28  ? 6.775   -21.816 -33.902 1.00 54.04 ? 28  THR A CG2 1 
ATOM   172  N N   . GLU A 1 29  ? 9.326   -23.978 -31.482 1.00 74.20 ? 29  GLU A N   1 
ATOM   173  C CA  . GLU A 1 29  ? 10.810  -24.028 -31.636 1.00 76.75 ? 29  GLU A CA  1 
ATOM   174  C C   . GLU A 1 29  ? 11.151  -23.494 -33.028 1.00 75.94 ? 29  GLU A C   1 
ATOM   175  O O   . GLU A 1 29  ? 11.919  -22.530 -33.112 1.00 74.24 ? 29  GLU A O   1 
ATOM   176  C CB  . GLU A 1 29  ? 11.343  -25.460 -31.488 1.00 75.64 ? 29  GLU A CB  1 
ATOM   177  C CG  . GLU A 1 29  ? 11.002  -26.126 -30.162 1.00 78.64 ? 29  GLU A CG  1 
ATOM   178  C CD  . GLU A 1 29  ? 12.107  -26.127 -29.115 1.00 82.05 ? 29  GLU A CD  1 
ATOM   179  O OE1 . GLU A 1 29  ? 13.200  -26.658 -29.407 1.00 80.58 ? 29  GLU A OE1 1 
ATOM   180  O OE2 . GLU A 1 29  ? 11.867  -25.609 -27.999 1.00 86.41 ? 29  GLU A OE2 1 
ATOM   181  N N   . ASN A 1 30  ? 10.539  -24.098 -34.057 1.00 86.05 ? 30  ASN A N   1 
ATOM   182  C CA  . ASN A 1 30  ? 10.618  -23.703 -35.491 1.00 86.20 ? 30  ASN A CA  1 
ATOM   183  C C   . ASN A 1 30  ? 10.510  -22.178 -35.591 1.00 85.37 ? 30  ASN A C   1 
ATOM   184  O O   . ASN A 1 30  ? 10.428  -21.698 -36.737 1.00 86.66 ? 30  ASN A O   1 
ATOM   185  C CB  . ASN A 1 30  ? 9.525   -24.381 -36.334 1.00 83.19 ? 30  ASN A CB  1 
ATOM   186  C CG  . ASN A 1 30  ? 9.707   -25.877 -36.525 1.00 84.23 ? 30  ASN A CG  1 
ATOM   187  O OD1 . ASN A 1 30  ? 8.866   -26.531 -37.134 1.00 85.95 ? 30  ASN A OD1 1 
ATOM   188  N ND2 . ASN A 1 30  ? 10.794  -26.442 -36.024 1.00 85.14 ? 30  ASN A ND2 1 
ATOM   189  N N   . ASN A 1 34  ? 4.931   -24.568 -41.816 1.00 57.62 ? 34  ASN A N   1 
ATOM   190  C CA  . ASN A 1 34  ? 3.681   -25.365 -41.637 1.00 55.31 ? 34  ASN A CA  1 
ATOM   191  C C   . ASN A 1 34  ? 3.683   -26.000 -40.229 1.00 50.18 ? 34  ASN A C   1 
ATOM   192  O O   . ASN A 1 34  ? 3.427   -27.216 -40.100 1.00 47.03 ? 34  ASN A O   1 
ATOM   193  C CB  . ASN A 1 34  ? 3.509   -26.393 -42.767 1.00 64.35 ? 34  ASN A CB  1 
ATOM   194  C CG  . ASN A 1 34  ? 2.359   -26.101 -43.721 1.00 79.07 ? 34  ASN A CG  1 
ATOM   195  O OD1 . ASN A 1 34  ? 1.767   -25.018 -43.704 1.00 82.41 ? 34  ASN A OD1 1 
ATOM   196  N ND2 . ASN A 1 34  ? 2.027   -27.070 -44.565 1.00 71.44 ? 34  ASN A ND2 1 
ATOM   197  N N   . SER A 1 35  ? 3.931   -25.193 -39.195 1.00 41.79 ? 35  SER A N   1 
ATOM   198  C CA  . SER A 1 35  ? 4.264   -25.641 -37.825 1.00 41.33 ? 35  SER A CA  1 
ATOM   199  C C   . SER A 1 35  ? 3.141   -25.279 -36.846 1.00 36.03 ? 35  SER A C   1 
ATOM   200  O O   . SER A 1 35  ? 2.182   -24.638 -37.271 1.00 34.76 ? 35  SER A O   1 
ATOM   201  C CB  . SER A 1 35  ? 5.578   -25.067 -37.404 1.00 42.41 ? 35  SER A CB  1 
ATOM   202  O OG  . SER A 1 35  ? 5.377   -23.827 -36.775 1.00 46.17 ? 35  SER A OG  1 
ATOM   203  N N   . GLY A 1 36  ? 3.259   -25.723 -35.594 1.00 34.99 ? 36  GLY A N   1 
ATOM   204  C CA  . GLY A 1 36  ? 2.185   -25.654 -34.585 1.00 32.71 ? 36  GLY A CA  1 
ATOM   205  C C   . GLY A 1 36  ? 2.451   -26.503 -33.352 1.00 29.08 ? 36  GLY A C   1 
ATOM   206  O O   . GLY A 1 36  ? 3.242   -27.445 -33.422 1.00 32.20 ? 36  GLY A O   1 
ATOM   207  N N   . THR A 1 37  ? 1.835   -26.119 -32.239 1.00 27.60 ? 37  THR A N   1 
ATOM   208  C CA  . THR A 1 37  ? 1.944   -26.756 -30.911 1.00 27.06 ? 37  THR A CA  1 
ATOM   209  C C   . THR A 1 37  ? 0.529   -27.001 -30.381 1.00 28.32 ? 37  THR A C   1 
ATOM   210  O O   . THR A 1 37  ? -0.395  -26.198 -30.651 1.00 25.86 ? 37  THR A O   1 
ATOM   211  C CB  . THR A 1 37  ? 2.754   -25.916 -29.917 1.00 29.53 ? 37  THR A CB  1 
ATOM   212  O OG1 . THR A 1 37  ? 2.097   -24.647 -29.794 1.00 31.97 ? 37  THR A OG1 1 
ATOM   213  C CG2 . THR A 1 37  ? 4.204   -25.758 -30.325 1.00 28.84 ? 37  THR A CG2 1 
ATOM   214  N N   . LEU A 1 38  ? 0.381   -28.111 -29.671 1.00 28.77 ? 38  LEU A N   1 
ATOM   215  C CA  . LEU A 1 38  ? -0.893  -28.583 -29.095 1.00 27.69 ? 38  LEU A CA  1 
ATOM   216  C C   . LEU A 1 38  ? -1.420  -27.491 -28.205 1.00 26.17 ? 38  LEU A C   1 
ATOM   217  O O   . LEU A 1 38  ? -0.580  -26.880 -27.504 1.00 23.41 ? 38  LEU A O   1 
ATOM   218  C CB  . LEU A 1 38  ? -0.631  -29.851 -28.287 1.00 26.94 ? 38  LEU A CB  1 
ATOM   219  C CG  . LEU A 1 38  ? -0.457  -31.090 -29.150 1.00 25.54 ? 38  LEU A CG  1 
ATOM   220  C CD1 . LEU A 1 38  ? 0.026   -32.271 -28.324 1.00 25.20 ? 38  LEU A CD1 1 
ATOM   221  C CD2 . LEU A 1 38  ? -1.766  -31.405 -29.855 1.00 26.77 ? 38  LEU A CD2 1 
ATOM   222  N N   . ILE A 1 39  ? -2.732  -27.273 -28.254 1.00 25.39 ? 39  ILE A N   1 
ATOM   223  C CA  . ILE A 1 39  ? -3.436  -26.527 -27.176 1.00 28.20 ? 39  ILE A CA  1 
ATOM   224  C C   . ILE A 1 39  ? -3.776  -27.522 -26.059 1.00 29.81 ? 39  ILE A C   1 
ATOM   225  O O   . ILE A 1 39  ? -4.484  -28.526 -26.323 1.00 31.35 ? 39  ILE A O   1 
ATOM   226  C CB  . ILE A 1 39  ? -4.645  -25.753 -27.707 1.00 28.79 ? 39  ILE A CB  1 
ATOM   227  C CG1 . ILE A 1 39  ? -4.188  -24.695 -28.718 1.00 30.36 ? 39  ILE A CG1 1 
ATOM   228  C CG2 . ILE A 1 39  ? -5.442  -25.121 -26.566 1.00 26.93 ? 39  ILE A CG2 1 
ATOM   229  C CD1 . ILE A 1 39  ? -5.338  -23.955 -29.383 1.00 32.28 ? 39  ILE A CD1 1 
ATOM   230  N N   . ILE A 1 40  ? -3.206  -27.277 -24.876 1.00 28.86 ? 40  ILE A N   1 
ATOM   231  C CA  . ILE A 1 40  ? -3.279  -28.187 -23.707 1.00 29.38 ? 40  ILE A CA  1 
ATOM   232  C C   . ILE A 1 40  ? -4.204  -27.570 -22.683 1.00 28.22 ? 40  ILE A C   1 
ATOM   233  O O   . ILE A 1 40  ? -3.945  -26.444 -22.319 1.00 28.19 ? 40  ILE A O   1 
ATOM   234  C CB  . ILE A 1 40  ? -1.890  -28.418 -23.095 1.00 30.40 ? 40  ILE A CB  1 
ATOM   235  C CG1 . ILE A 1 40  ? -0.926  -28.971 -24.141 1.00 29.54 ? 40  ILE A CG1 1 
ATOM   236  C CG2 . ILE A 1 40  ? -2.003  -29.319 -21.867 1.00 30.58 ? 40  ILE A CG2 1 
ATOM   237  C CD1 . ILE A 1 40  ? -1.450  -30.191 -24.822 1.00 32.15 ? 40  ILE A CD1 1 
ATOM   238  N N   . PHE A 1 41  ? -5.202  -28.310 -22.208 1.00 28.78 ? 41  PHE A N   1 
ATOM   239  C CA  . PHE A 1 41  ? -5.961  -27.908 -20.993 1.00 30.09 ? 41  PHE A CA  1 
ATOM   240  C C   . PHE A 1 41  ? -5.327  -28.589 -19.779 1.00 30.14 ? 41  PHE A C   1 
ATOM   241  O O   . PHE A 1 41  ? -4.992  -29.781 -19.889 1.00 30.66 ? 41  PHE A O   1 
ATOM   242  C CB  . PHE A 1 41  ? -7.448  -28.220 -21.132 1.00 28.02 ? 41  PHE A CB  1 
ATOM   243  C CG  . PHE A 1 41  ? -8.220  -27.173 -21.888 1.00 27.35 ? 41  PHE A CG  1 
ATOM   244  C CD1 . PHE A 1 41  ? -8.171  -27.114 -23.279 1.00 26.81 ? 41  PHE A CD1 1 
ATOM   245  C CD2 . PHE A 1 41  ? -9.025  -26.270 -21.205 1.00 27.18 ? 41  PHE A CD2 1 
ATOM   246  C CE1 . PHE A 1 41  ? -8.925  -26.167 -23.964 1.00 27.42 ? 41  PHE A CE1 1 
ATOM   247  C CE2 . PHE A 1 41  ? -9.740  -25.293 -21.892 1.00 28.70 ? 41  PHE A CE2 1 
ATOM   248  C CZ  . PHE A 1 41  ? -9.716  -25.265 -23.272 1.00 28.08 ? 41  PHE A CZ  1 
ATOM   249  N N   . ASP A 1 42  ? -5.141  -27.833 -18.690 1.00 32.65 ? 42  ASP A N   1 
ATOM   250  C CA  . ASP A 1 42  ? -4.362  -28.241 -17.491 1.00 37.32 ? 42  ASP A CA  1 
ATOM   251  C C   . ASP A 1 42  ? -4.641  -27.275 -16.339 1.00 34.71 ? 42  ASP A C   1 
ATOM   252  O O   . ASP A 1 42  ? -5.202  -26.205 -16.590 1.00 36.01 ? 42  ASP A O   1 
ATOM   253  C CB  . ASP A 1 42  ? -2.851  -28.269 -17.774 1.00 43.06 ? 42  ASP A CB  1 
ATOM   254  C CG  . ASP A 1 42  ? -2.128  -29.393 -17.045 1.00 51.11 ? 42  ASP A CG  1 
ATOM   255  O OD1 . ASP A 1 42  ? -0.986  -29.713 -17.452 1.00 59.28 ? 42  ASP A OD1 1 
ATOM   256  O OD2 . ASP A 1 42  ? -2.731  -29.979 -16.104 1.00 48.51 ? 42  ASP A OD2 1 
ATOM   257  N N   . GLN A 1 43  ? -4.243  -27.664 -15.131 1.00 36.00 ? 43  GLN A N   1 
ATOM   258  C CA  . GLN A 1 43  ? -4.248  -26.827 -13.907 1.00 40.89 ? 43  GLN A CA  1 
ATOM   259  C C   . GLN A 1 43  ? -2.809  -26.403 -13.589 1.00 41.37 ? 43  GLN A C   1 
ATOM   260  O O   . GLN A 1 43  ? -2.470  -26.278 -12.427 1.00 42.84 ? 43  GLN A O   1 
ATOM   261  C CB  . GLN A 1 43  ? -4.846  -27.618 -12.745 1.00 41.33 ? 43  GLN A CB  1 
ATOM   262  C CG  . GLN A 1 43  ? -6.359  -27.596 -12.728 1.00 47.53 ? 43  GLN A CG  1 
ATOM   263  C CD  . GLN A 1 43  ? -6.881  -28.424 -11.582 1.00 48.47 ? 43  GLN A CD  1 
ATOM   264  O OE1 . GLN A 1 43  ? -7.583  -27.932 -10.706 1.00 55.00 ? 43  GLN A OE1 1 
ATOM   265  N NE2 . GLN A 1 43  ? -6.526  -29.692 -11.572 1.00 50.20 ? 43  GLN A NE2 1 
ATOM   266  N N   . SER A 1 44  ? -1.965  -26.240 -14.594 1.00 42.40 ? 44  SER A N   1 
ATOM   267  C CA  . SER A 1 44  ? -0.641  -25.597 -14.435 1.00 43.87 ? 44  SER A CA  1 
ATOM   268  C C   . SER A 1 44  ? -0.298  -24.885 -15.737 1.00 38.47 ? 44  SER A C   1 
ATOM   269  O O   . SER A 1 44  ? -0.603  -25.437 -16.780 1.00 40.28 ? 44  SER A O   1 
ATOM   270  C CB  . SER A 1 44  ? 0.413   -26.609 -14.052 1.00 45.84 ? 44  SER A CB  1 
ATOM   271  O OG  . SER A 1 44  ? 1.685   -26.210 -14.540 1.00 51.92 ? 44  SER A OG  1 
ATOM   272  N N   . THR A 1 45  ? 0.334   -23.718 -15.658 1.00 43.92 ? 45  THR A N   1 
ATOM   273  C CA  . THR A 1 45  ? 0.811   -22.929 -16.822 1.00 40.95 ? 45  THR A CA  1 
ATOM   274  C C   . THR A 1 45  ? 2.291   -23.188 -17.074 1.00 39.62 ? 45  THR A C   1 
ATOM   275  O O   . THR A 1 45  ? 3.098   -23.047 -16.162 1.00 38.62 ? 45  THR A O   1 
ATOM   276  C CB  . THR A 1 45  ? 0.584   -21.443 -16.581 1.00 45.56 ? 45  THR A CB  1 
ATOM   277  O OG1 . THR A 1 45  ? -0.768  -21.340 -16.141 1.00 45.46 ? 45  THR A OG1 1 
ATOM   278  C CG2 . THR A 1 45  ? 0.849   -20.611 -17.818 1.00 49.87 ? 45  THR A CG2 1 
ATOM   279  N N   . PRO A 1 46  ? 2.691   -23.540 -18.321 1.00 46.86 ? 46  PRO A N   1 
ATOM   280  C CA  . PRO A 1 46  ? 4.089   -23.853 -18.637 1.00 45.96 ? 46  PRO A CA  1 
ATOM   281  C C   . PRO A 1 46  ? 4.893   -22.611 -19.051 1.00 48.57 ? 46  PRO A C   1 
ATOM   282  O O   . PRO A 1 46  ? 5.480   -22.598 -20.127 1.00 55.62 ? 46  PRO A O   1 
ATOM   283  C CB  . PRO A 1 46  ? 3.933   -24.849 -19.806 1.00 45.32 ? 46  PRO A CB  1 
ATOM   284  C CG  . PRO A 1 46  ? 2.739   -24.299 -20.571 1.00 44.88 ? 46  PRO A CG  1 
ATOM   285  C CD  . PRO A 1 46  ? 1.820   -23.719 -19.503 1.00 44.76 ? 46  PRO A CD  1 
ATOM   286  N N   . GLY A 1 47  ? 4.906   -21.590 -18.197 1.00 44.82 ? 47  GLY A N   1 
ATOM   287  C CA  . GLY A 1 47  ? 5.686   -20.369 -18.444 1.00 41.86 ? 47  GLY A CA  1 
ATOM   288  C C   . GLY A 1 47  ? 4.808   -19.140 -18.453 1.00 43.14 ? 47  GLY A C   1 
ATOM   289  O O   . GLY A 1 47  ? 3.571   -19.264 -18.532 1.00 48.06 ? 47  GLY A O   1 
ATOM   290  N N   . GLN A 1 48  ? 5.440   -17.981 -18.381 1.00 46.70 ? 48  GLN A N   1 
ATOM   291  C CA  . GLN A 1 48  ? 4.763   -16.661 -18.314 1.00 51.41 ? 48  GLN A CA  1 
ATOM   292  C C   . GLN A 1 48  ? 3.758   -16.508 -19.466 1.00 45.12 ? 48  GLN A C   1 
ATOM   293  O O   . GLN A 1 48  ? 4.156   -16.555 -20.666 1.00 41.01 ? 48  GLN A O   1 
ATOM   294  C CB  . GLN A 1 48  ? 5.802   -15.546 -18.350 1.00 52.08 ? 48  GLN A CB  1 
ATOM   295  C CG  . GLN A 1 48  ? 5.270   -14.230 -17.830 1.00 56.55 ? 48  GLN A CG  1 
ATOM   296  C CD  . GLN A 1 48  ? 6.429   -13.348 -17.455 1.00 56.63 ? 48  GLN A CD  1 
ATOM   297  O OE1 . GLN A 1 48  ? 7.529   -13.505 -17.979 1.00 57.12 ? 48  GLN A OE1 1 
ATOM   298  N NE2 . GLN A 1 48  ? 6.195   -12.447 -16.517 1.00 57.28 ? 48  GLN A NE2 1 
ATOM   299  N N   . ASP A 1 49  ? 2.491   -16.375 -19.084 1.00 41.88 ? 49  ASP A N   1 
ATOM   300  C CA  . ASP A 1 49  ? 1.366   -15.999 -19.968 1.00 37.45 ? 49  ASP A CA  1 
ATOM   301  C C   . ASP A 1 49  ? 1.186   -17.001 -21.121 1.00 32.39 ? 49  ASP A C   1 
ATOM   302  O O   . ASP A 1 49  ? 0.575   -16.609 -22.130 1.00 30.95 ? 49  ASP A O   1 
ATOM   303  C CB  . ASP A 1 49  ? 1.600   -14.584 -20.488 1.00 40.11 ? 49  ASP A CB  1 
ATOM   304  C CG  . ASP A 1 49  ? 1.755   -13.556 -19.395 1.00 36.18 ? 49  ASP A CG  1 
ATOM   305  O OD1 . ASP A 1 49  ? 0.918   -13.554 -18.482 1.00 38.35 ? 49  ASP A OD1 1 
ATOM   306  O OD2 . ASP A 1 49  ? 2.697   -12.762 -19.496 1.00 32.49 ? 49  ASP A OD2 1 
ATOM   307  N N   . ALA A 1 50  ? 1.628   -18.249 -20.970 1.00 27.96 ? 50  ALA A N   1 
ATOM   308  C CA  . ALA A 1 50  ? 1.273   -19.339 -21.898 1.00 31.14 ? 50  ALA A CA  1 
ATOM   309  C C   . ALA A 1 50  ? -0.212  -19.706 -21.744 1.00 29.66 ? 50  ALA A C   1 
ATOM   310  O O   . ALA A 1 50  ? -0.733  -20.418 -22.605 1.00 32.02 ? 50  ALA A O   1 
ATOM   311  C CB  . ALA A 1 50  ? 2.170   -20.524 -21.664 1.00 34.71 ? 50  ALA A CB  1 
ATOM   312  N N   . ASP A 1 51  ? -0.869  -19.200 -20.703 1.00 29.12 ? 51  ASP A N   1 
ATOM   313  C CA  . ASP A 1 51  ? -2.302  -19.419 -20.409 1.00 29.53 ? 51  ASP A CA  1 
ATOM   314  C C   . ASP A 1 51  ? -3.104  -18.136 -20.645 1.00 28.84 ? 51  ASP A C   1 
ATOM   315  O O   . ASP A 1 51  ? -4.285  -18.067 -20.202 1.00 28.69 ? 51  ASP A O   1 
ATOM   316  C CB  . ASP A 1 51  ? -2.458  -19.879 -18.963 1.00 30.85 ? 51  ASP A CB  1 
ATOM   317  C CG  . ASP A 1 51  ? -2.038  -18.852 -17.931 1.00 33.11 ? 51  ASP A CG  1 
ATOM   318  O OD1 . ASP A 1 51  ? -1.281  -17.881 -18.289 1.00 32.97 ? 51  ASP A OD1 1 
ATOM   319  O OD2 . ASP A 1 51  ? -2.470  -19.026 -16.783 1.00 33.35 ? 51  ASP A OD2 1 
ATOM   320  N N   . ARG A 1 52  ? -2.494  -17.153 -21.301 1.00 29.83 ? 52  ARG A N   1 
ATOM   321  C CA  . ARG A 1 52  ? -3.108  -15.826 -21.555 1.00 31.37 ? 52  ARG A CA  1 
ATOM   322  C C   . ARG A 1 52  ? -3.351  -15.647 -23.060 1.00 31.54 ? 52  ARG A C   1 
ATOM   323  O O   . ARG A 1 52  ? -2.416  -15.828 -23.868 1.00 29.48 ? 52  ARG A O   1 
ATOM   324  C CB  . ARG A 1 52  ? -2.222  -14.716 -20.994 1.00 35.45 ? 52  ARG A CB  1 
ATOM   325  C CG  . ARG A 1 52  ? -1.972  -14.831 -19.497 1.00 41.48 ? 52  ARG A CG  1 
ATOM   326  C CD  . ARG A 1 52  ? -3.291  -14.936 -18.778 1.00 45.86 ? 52  ARG A CD  1 
ATOM   327  N NE  . ARG A 1 52  ? -3.186  -15.086 -17.342 1.00 47.46 ? 52  ARG A NE  1 
ATOM   328  C CZ  . ARG A 1 52  ? -3.780  -14.306 -16.455 1.00 45.91 ? 52  ARG A CZ  1 
ATOM   329  N NH1 . ARG A 1 52  ? -4.499  -13.275 -16.838 1.00 48.52 ? 52  ARG A NH1 1 
ATOM   330  N NH2 . ARG A 1 52  ? -3.659  -14.555 -15.168 1.00 54.64 ? 52  ARG A NH2 1 
ATOM   331  N N   . TRP A 1 53  ? -4.576  -15.256 -23.380 1.00 28.80 ? 53  TRP A N   1 
ATOM   332  C CA  . TRP A 1 53  ? -5.172  -15.281 -24.729 1.00 27.50 ? 53  TRP A CA  1 
ATOM   333  C C   . TRP A 1 53  ? -5.752  -13.898 -25.019 1.00 26.12 ? 53  TRP A C   1 
ATOM   334  O O   . TRP A 1 53  ? -6.071  -13.163 -24.075 1.00 29.57 ? 53  TRP A O   1 
ATOM   335  C CB  . TRP A 1 53  ? -6.242  -16.379 -24.786 1.00 27.51 ? 53  TRP A CB  1 
ATOM   336  C CG  . TRP A 1 53  ? -5.736  -17.785 -24.634 1.00 24.53 ? 53  TRP A CG  1 
ATOM   337  C CD1 . TRP A 1 53  ? -5.595  -18.485 -23.477 1.00 26.13 ? 53  TRP A CD1 1 
ATOM   338  C CD2 . TRP A 1 53  ? -5.323  -18.683 -25.675 1.00 25.29 ? 53  TRP A CD2 1 
ATOM   339  N NE1 . TRP A 1 53  ? -5.108  -19.744 -23.724 1.00 27.80 ? 53  TRP A NE1 1 
ATOM   340  C CE2 . TRP A 1 53  ? -4.933  -19.894 -25.064 1.00 25.38 ? 53  TRP A CE2 1 
ATOM   341  C CE3 . TRP A 1 53  ? -5.210  -18.572 -27.059 1.00 25.46 ? 53  TRP A CE3 1 
ATOM   342  C CZ2 . TRP A 1 53  ? -4.493  -20.992 -25.784 1.00 25.54 ? 53  TRP A CZ2 1 
ATOM   343  C CZ3 . TRP A 1 53  ? -4.775  -19.658 -27.776 1.00 25.79 ? 53  TRP A CZ3 1 
ATOM   344  C CH2 . TRP A 1 53  ? -4.425  -20.850 -27.148 1.00 26.34 ? 53  TRP A CH2 1 
ATOM   345  N N   . LEU A 1 54  ? -5.770  -13.521 -26.282 1.00 27.39 ? 54  LEU A N   1 
ATOM   346  C CA  . LEU A 1 54  ? -6.348  -12.255 -26.776 1.00 26.18 ? 54  LEU A CA  1 
ATOM   347  C C   . LEU A 1 54  ? -7.369  -12.584 -27.865 1.00 26.00 ? 54  LEU A C   1 
ATOM   348  O O   . LEU A 1 54  ? -6.970  -13.167 -28.895 1.00 29.31 ? 54  LEU A O   1 
ATOM   349  C CB  . LEU A 1 54  ? -5.214  -11.366 -27.296 1.00 27.02 ? 54  LEU A CB  1 
ATOM   350  C CG  . LEU A 1 54  ? -5.661  -9.989  -27.790 1.00 28.45 ? 54  LEU A CG  1 
ATOM   351  C CD1 . LEU A 1 54  ? -6.459  -9.267  -26.705 1.00 28.77 ? 54  LEU A CD1 1 
ATOM   352  C CD2 . LEU A 1 54  ? -4.472  -9.161  -28.232 1.00 29.66 ? 54  LEU A CD2 1 
ATOM   353  N N   . ILE A 1 55  ? -8.640  -12.231 -27.648 1.00 27.62 ? 55  ILE A N   1 
ATOM   354  C CA  . ILE A 1 55  ? -9.753  -12.473 -28.619 1.00 28.20 ? 55  ILE A CA  1 
ATOM   355  C C   . ILE A 1 55  ? -10.101 -11.158 -29.338 1.00 29.74 ? 55  ILE A C   1 
ATOM   356  O O   . ILE A 1 55  ? -10.362 -10.142 -28.662 1.00 30.45 ? 55  ILE A O   1 
ATOM   357  C CB  . ILE A 1 55  ? -10.962 -13.126 -27.933 1.00 28.70 ? 55  ILE A CB  1 
ATOM   358  C CG1 . ILE A 1 55  ? -10.524 -14.328 -27.088 1.00 31.66 ? 55  ILE A CG1 1 
ATOM   359  C CG2 . ILE A 1 55  ? -12.015 -13.502 -28.963 1.00 30.65 ? 55  ILE A CG2 1 
ATOM   360  C CD1 . ILE A 1 55  ? -11.594 -14.900 -26.228 1.00 32.20 ? 55  ILE A CD1 1 
ATOM   361  N N   . HIS A 1 56  ? -10.071 -11.184 -30.675 1.00 29.43 ? 56  HIS A N   1 
ATOM   362  C CA  . HIS A 1 56  ? -10.473 -10.061 -31.559 1.00 31.57 ? 56  HIS A CA  1 
ATOM   363  C C   . HIS A 1 56  ? -11.592 -10.494 -32.516 1.00 34.08 ? 56  HIS A C   1 
ATOM   364  O O   . HIS A 1 56  ? -11.720 -11.690 -32.792 1.00 32.25 ? 56  HIS A O   1 
ATOM   365  C CB  . HIS A 1 56  ? -9.294  -9.558  -32.385 1.00 31.80 ? 56  HIS A CB  1 
ATOM   366  C CG  . HIS A 1 56  ? -8.237  -8.860  -31.610 1.00 31.65 ? 56  HIS A CG  1 
ATOM   367  N ND1 . HIS A 1 56  ? -8.495  -8.252  -30.405 1.00 29.65 ? 56  HIS A ND1 1 
ATOM   368  C CD2 . HIS A 1 56  ? -6.942  -8.602  -31.915 1.00 32.79 ? 56  HIS A CD2 1 
ATOM   369  C CE1 . HIS A 1 56  ? -7.390  -7.657  -29.983 1.00 32.73 ? 56  HIS A CE1 1 
ATOM   370  N NE2 . HIS A 1 56  ? -6.416  -7.862  -30.888 1.00 31.83 ? 56  HIS A NE2 1 
ATOM   371  N N   . ASN A 1 57  ? -12.349 -9.515  -33.009 1.00 37.32 ? 57  ASN A N   1 
ATOM   372  C CA  . ASN A 1 57  ? -13.211 -9.636  -34.207 1.00 39.27 ? 57  ASN A CA  1 
ATOM   373  C C   . ASN A 1 57  ? -12.338 -10.033 -35.405 1.00 36.14 ? 57  ASN A C   1 
ATOM   374  O O   . ASN A 1 57  ? -11.199 -9.553  -35.514 1.00 32.49 ? 57  ASN A O   1 
ATOM   375  C CB  . ASN A 1 57  ? -14.000 -8.351  -34.481 1.00 42.34 ? 57  ASN A CB  1 
ATOM   376  C CG  . ASN A 1 57  ? -15.082 -8.120  -33.447 1.00 47.84 ? 57  ASN A CG  1 
ATOM   377  O OD1 . ASN A 1 57  ? -15.114 -7.076  -32.796 1.00 51.47 ? 57  ASN A OD1 1 
ATOM   378  N ND2 . ASN A 1 57  ? -15.975 -9.090  -33.290 1.00 58.04 ? 57  ASN A ND2 1 
ATOM   379  N N   . TYR A 1 58  ? -12.863 -10.952 -36.210 1.00 36.35 ? 58  TYR A N   1 
ATOM   380  C CA  . TYR A 1 58  ? -12.396 -11.322 -37.562 1.00 39.90 ? 58  TYR A CA  1 
ATOM   381  C C   . TYR A 1 58  ? -13.657 -11.679 -38.379 1.00 44.14 ? 58  TYR A C   1 
ATOM   382  O O   . TYR A 1 58  ? -14.343 -12.667 -38.008 1.00 38.11 ? 58  TYR A O   1 
ATOM   383  C CB  . TYR A 1 58  ? -11.343 -12.424 -37.471 1.00 39.87 ? 58  TYR A CB  1 
ATOM   384  C CG  . TYR A 1 58  ? -10.724 -12.700 -38.812 1.00 41.83 ? 58  TYR A CG  1 
ATOM   385  C CD1 . TYR A 1 58  ? -9.800  -11.837 -39.381 1.00 39.63 ? 58  TYR A CD1 1 
ATOM   386  C CD2 . TYR A 1 58  ? -11.154 -13.774 -39.563 1.00 45.07 ? 58  TYR A CD2 1 
ATOM   387  C CE1 . TYR A 1 58  ? -9.296  -12.055 -40.656 1.00 39.35 ? 58  TYR A CE1 1 
ATOM   388  C CE2 . TYR A 1 58  ? -10.665 -14.003 -40.839 1.00 47.80 ? 58  TYR A CE2 1 
ATOM   389  C CZ  . TYR A 1 58  ? -9.727  -13.147 -41.388 1.00 42.56 ? 58  TYR A CZ  1 
ATOM   390  O OH  . TYR A 1 58  ? -9.246  -13.422 -42.635 1.00 41.11 ? 58  TYR A OH  1 
ATOM   391  N N   . LEU A 1 59  ? -14.033 -10.813 -39.338 1.00 40.00 ? 59  LEU A N   1 
ATOM   392  C CA  . LEU A 1 59  ? -15.231 -10.940 -40.209 1.00 38.34 ? 59  LEU A CA  1 
ATOM   393  C C   . LEU A 1 59  ? -16.450 -11.318 -39.358 1.00 36.18 ? 59  LEU A C   1 
ATOM   394  O O   . LEU A 1 59  ? -16.748 -10.587 -38.422 1.00 35.36 ? 59  LEU A O   1 
ATOM   395  C CB  . LEU A 1 59  ? -14.903 -11.955 -41.312 1.00 39.19 ? 59  LEU A CB  1 
ATOM   396  C CG  . LEU A 1 59  ? -13.478 -11.828 -41.862 1.00 44.31 ? 59  LEU A CG  1 
ATOM   397  C CD1 . LEU A 1 59  ? -13.211 -12.810 -42.998 1.00 39.76 ? 59  LEU A CD1 1 
ATOM   398  C CD2 . LEU A 1 59  ? -13.179 -10.396 -42.313 1.00 46.50 ? 59  LEU A CD2 1 
ATOM   399  N N   . ASP A 1 60  ? -17.128 -12.420 -39.669 1.00 37.96 ? 60  ASP A N   1 
ATOM   400  C CA  . ASP A 1 60  ? -18.376 -12.859 -38.987 1.00 39.25 ? 60  ASP A CA  1 
ATOM   401  C C   . ASP A 1 60  ? -18.046 -13.621 -37.690 1.00 38.52 ? 60  ASP A C   1 
ATOM   402  O O   . ASP A 1 60  ? -18.957 -14.072 -37.034 1.00 39.08 ? 60  ASP A O   1 
ATOM   403  C CB  . ASP A 1 60  ? -19.254 -13.688 -39.940 1.00 40.37 ? 60  ASP A CB  1 
ATOM   404  C CG  . ASP A 1 60  ? -18.512 -14.770 -40.712 1.00 45.38 ? 60  ASP A CG  1 
ATOM   405  O OD1 . ASP A 1 60  ? -17.302 -14.600 -40.966 1.00 46.34 ? 60  ASP A OD1 1 
ATOM   406  O OD2 . ASP A 1 60  ? -19.139 -15.784 -41.040 1.00 51.33 ? 60  ASP A OD2 1 
ATOM   407  N N   . GLY A 1 61  ? -16.785 -13.778 -37.319 1.00 37.11 ? 61  GLY A N   1 
ATOM   408  C CA  . GLY A 1 61  ? -16.435 -14.419 -36.045 1.00 37.03 ? 61  GLY A CA  1 
ATOM   409  C C   . GLY A 1 61  ? -15.255 -13.748 -35.379 1.00 39.21 ? 61  GLY A C   1 
ATOM   410  O O   . GLY A 1 61  ? -15.188 -12.486 -35.373 1.00 39.05 ? 61  GLY A O   1 
ATOM   411  N N   . TYR A 1 62  ? -14.338 -14.574 -34.880 1.00 34.35 ? 62  TYR A N   1 
ATOM   412  C CA  . TYR A 1 62  ? -13.293 -14.192 -33.908 1.00 31.65 ? 62  TYR A CA  1 
ATOM   413  C C   . TYR A 1 62  ? -12.020 -14.926 -34.245 1.00 30.21 ? 62  TYR A C   1 
ATOM   414  O O   . TYR A 1 62  ? -12.114 -15.976 -34.880 1.00 30.06 ? 62  TYR A O   1 
ATOM   415  C CB  . TYR A 1 62  ? -13.715 -14.526 -32.482 1.00 31.61 ? 62  TYR A CB  1 
ATOM   416  C CG  . TYR A 1 62  ? -15.026 -13.883 -32.116 1.00 31.77 ? 62  TYR A CG  1 
ATOM   417  C CD1 . TYR A 1 62  ? -16.201 -14.586 -32.265 1.00 34.61 ? 62  TYR A CD1 1 
ATOM   418  C CD2 . TYR A 1 62  ? -15.100 -12.567 -31.669 1.00 31.79 ? 62  TYR A CD2 1 
ATOM   419  C CE1 . TYR A 1 62  ? -17.427 -14.014 -31.970 1.00 38.01 ? 62  TYR A CE1 1 
ATOM   420  C CE2 . TYR A 1 62  ? -16.319 -11.978 -31.377 1.00 32.57 ? 62  TYR A CE2 1 
ATOM   421  C CZ  . TYR A 1 62  ? -17.488 -12.707 -31.531 1.00 34.77 ? 62  TYR A CZ  1 
ATOM   422  O OH  . TYR A 1 62  ? -18.712 -12.190 -31.246 1.00 33.11 ? 62  TYR A OH  1 
ATOM   423  N N   . LYS A 1 63  ? -10.901 -14.333 -33.849 1.00 30.30 ? 63  LYS A N   1 
ATOM   424  C CA  . LYS A 1 63  ? -9.573  -14.984 -33.831 1.00 30.08 ? 63  LYS A CA  1 
ATOM   425  C C   . LYS A 1 63  ? -9.102  -14.997 -32.377 1.00 27.95 ? 63  LYS A C   1 
ATOM   426  O O   . LYS A 1 63  ? -9.466  -14.073 -31.608 1.00 25.83 ? 63  LYS A O   1 
ATOM   427  C CB  . LYS A 1 63  ? -8.578  -14.266 -34.751 1.00 32.43 ? 63  LYS A CB  1 
ATOM   428  C CG  . LYS A 1 63  ? -8.551  -12.754 -34.634 1.00 36.47 ? 63  LYS A CG  1 
ATOM   429  C CD  . LYS A 1 63  ? -8.024  -12.085 -35.877 1.00 39.97 ? 63  LYS A CD  1 
ATOM   430  C CE  . LYS A 1 63  ? -7.792  -10.598 -35.706 1.00 43.19 ? 63  LYS A CE  1 
ATOM   431  N NZ  . LYS A 1 63  ? -6.628  -10.167 -36.514 1.00 43.10 ? 63  LYS A NZ  1 
ATOM   432  N N   . ILE A 1 64  ? -8.323  -16.014 -32.035 1.00 25.13 ? 64  ILE A N   1 
ATOM   433  C CA  . ILE A 1 64  ? -7.941  -16.347 -30.640 1.00 25.50 ? 64  ILE A CA  1 
ATOM   434  C C   . ILE A 1 64  ? -6.414  -16.474 -30.609 1.00 25.90 ? 64  ILE A C   1 
ATOM   435  O O   . ILE A 1 64  ? -5.873  -17.416 -31.211 1.00 28.11 ? 64  ILE A O   1 
ATOM   436  C CB  . ILE A 1 64  ? -8.675  -17.619 -30.168 1.00 24.91 ? 64  ILE A CB  1 
ATOM   437  C CG1 . ILE A 1 64  ? -10.180 -17.474 -30.405 1.00 25.45 ? 64  ILE A CG1 1 
ATOM   438  C CG2 . ILE A 1 64  ? -8.326  -17.954 -28.717 1.00 24.69 ? 64  ILE A CG2 1 
ATOM   439  C CD1 . ILE A 1 64  ? -11.020 -18.594 -29.857 1.00 24.50 ? 64  ILE A CD1 1 
ATOM   440  N N   . PHE A 1 65  ? -5.767  -15.522 -29.954 1.00 24.87 ? 65  PHE A N   1 
ATOM   441  C CA  . PHE A 1 65  ? -4.306  -15.325 -29.969 1.00 24.74 ? 65  PHE A CA  1 
ATOM   442  C C   . PHE A 1 65  ? -3.750  -15.629 -28.583 1.00 24.01 ? 65  PHE A C   1 
ATOM   443  O O   . PHE A 1 65  ? -4.342  -15.159 -27.579 1.00 27.70 ? 65  PHE A O   1 
ATOM   444  C CB  . PHE A 1 65  ? -4.010  -13.902 -30.439 1.00 25.64 ? 65  PHE A CB  1 
ATOM   445  C CG  . PHE A 1 65  ? -2.541  -13.615 -30.542 1.00 24.36 ? 65  PHE A CG  1 
ATOM   446  C CD1 . PHE A 1 65  ? -1.837  -13.999 -31.668 1.00 24.18 ? 65  PHE A CD1 1 
ATOM   447  C CD2 . PHE A 1 65  ? -1.864  -12.994 -29.516 1.00 21.75 ? 65  PHE A CD2 1 
ATOM   448  C CE1 . PHE A 1 65  ? -0.478  -13.733 -31.771 1.00 23.93 ? 65  PHE A CE1 1 
ATOM   449  C CE2 . PHE A 1 65  ? -0.506  -12.727 -29.631 1.00 23.84 ? 65  PHE A CE2 1 
ATOM   450  C CZ  . PHE A 1 65  ? 0.185   -13.099 -30.756 1.00 22.84 ? 65  PHE A CZ  1 
ATOM   451  N N   . ASN A 1 66  ? -2.708  -16.452 -28.514 1.00 22.18 ? 66  ASN A N   1 
ATOM   452  C CA  . ASN A 1 66  ? -2.008  -16.775 -27.244 1.00 24.72 ? 66  ASN A CA  1 
ATOM   453  C C   . ASN A 1 66  ? -0.882  -15.756 -27.088 1.00 24.86 ? 66  ASN A C   1 
ATOM   454  O O   . ASN A 1 66  ? -0.039  -15.686 -27.989 1.00 25.93 ? 66  ASN A O   1 
ATOM   455  C CB  . ASN A 1 66  ? -1.500  -18.216 -27.198 1.00 26.68 ? 66  ASN A CB  1 
ATOM   456  C CG  . ASN A 1 66  ? -0.944  -18.594 -25.846 1.00 29.32 ? 66  ASN A CG  1 
ATOM   457  O OD1 . ASN A 1 66  ? 0.171   -18.200 -25.504 1.00 30.35 ? 66  ASN A OD1 1 
ATOM   458  N ND2 . ASN A 1 66  ? -1.716  -19.342 -25.067 1.00 30.74 ? 66  ASN A ND2 1 
ATOM   459  N N   . MET A 1 67  ? -0.927  -14.932 -26.037 1.00 27.74 ? 67  MET A N   1 
ATOM   460  C CA  . MET A 1 67  ? 0.075   -13.860 -25.780 1.00 28.62 ? 67  MET A CA  1 
ATOM   461  C C   . MET A 1 67  ? 1.437   -14.503 -25.437 1.00 29.14 ? 67  MET A C   1 
ATOM   462  O O   . MET A 1 67  ? 2.504   -13.925 -25.787 1.00 29.16 ? 67  MET A O   1 
ATOM   463  C CB  . MET A 1 67  ? -0.354  -12.968 -24.615 1.00 32.49 ? 67  MET A CB  1 
ATOM   464  C CG  . MET A 1 67  ? -1.718  -12.331 -24.738 1.00 34.83 ? 67  MET A CG  1 
ATOM   465  S SD  . MET A 1 67  ? -1.697  -11.001 -25.867 1.00 47.64 ? 67  MET A SD  1 
ATOM   466  C CE  . MET A 1 67  ? -0.858  -9.729  -24.923 1.00 42.01 ? 67  MET A CE  1 
ATOM   467  N N   . GLY A 1 68  ? 1.420   -15.657 -24.765 1.00 27.46 ? 68  GLY A N   1 
ATOM   468  C CA  . GLY A 1 68  ? 2.643   -16.397 -24.431 1.00 28.50 ? 68  GLY A CA  1 
ATOM   469  C C   . GLY A 1 68  ? 3.363   -16.840 -25.681 1.00 27.23 ? 68  GLY A C   1 
ATOM   470  O O   . GLY A 1 68  ? 4.517   -16.456 -25.880 1.00 28.65 ? 68  GLY A O   1 
ATOM   471  N N   . SER A 1 69  ? 2.674   -17.574 -26.541 1.00 29.17 ? 69  SER A N   1 
ATOM   472  C CA  . SER A 1 69  ? 3.311   -18.360 -27.624 1.00 29.39 ? 69  SER A CA  1 
ATOM   473  C C   . SER A 1 69  ? 3.347   -17.551 -28.921 1.00 30.42 ? 69  SER A C   1 
ATOM   474  O O   . SER A 1 69  ? 4.108   -17.943 -29.823 1.00 30.20 ? 69  SER A O   1 
ATOM   475  C CB  . SER A 1 69  ? 2.592   -19.676 -27.794 1.00 29.95 ? 69  SER A CB  1 
ATOM   476  O OG  . SER A 1 69  ? 1.229   -19.481 -28.121 1.00 29.13 ? 69  SER A OG  1 
ATOM   477  N N   . ASN A 1 70  ? 2.542   -16.485 -29.015 1.00 30.15 ? 70  ASN A N   1 
ATOM   478  C CA  . ASN A 1 70  ? 2.292   -15.710 -30.263 1.00 32.51 ? 70  ASN A CA  1 
ATOM   479  C C   . ASN A 1 70  ? 1.621   -16.613 -31.303 1.00 30.54 ? 70  ASN A C   1 
ATOM   480  O O   . ASN A 1 70  ? 1.698   -16.274 -32.512 1.00 25.22 ? 70  ASN A O   1 
ATOM   481  C CB  . ASN A 1 70  ? 3.556   -15.044 -30.826 1.00 35.94 ? 70  ASN A CB  1 
ATOM   482  C CG  . ASN A 1 70  ? 3.718   -13.613 -30.357 1.00 41.13 ? 70  ASN A CG  1 
ATOM   483  O OD1 . ASN A 1 70  ? 3.607   -12.690 -31.167 1.00 46.58 ? 70  ASN A OD1 1 
ATOM   484  N ND2 . ASN A 1 70  ? 3.949   -13.417 -29.064 1.00 40.19 ? 70  ASN A ND2 1 
ATOM   485  N N   . ASN A 1 71  ? 0.913   -17.669 -30.873 1.00 30.03 ? 71  ASN A N   1 
ATOM   486  C CA  . ASN A 1 71  ? 0.220   -18.583 -31.825 1.00 28.99 ? 71  ASN A CA  1 
ATOM   487  C C   . ASN A 1 71  ? -1.274  -18.246 -31.919 1.00 27.92 ? 71  ASN A C   1 
ATOM   488  O O   . ASN A 1 71  ? -1.888  -17.765 -30.948 1.00 22.81 ? 71  ASN A O   1 
ATOM   489  C CB  . ASN A 1 71  ? 0.445   -20.058 -31.497 1.00 31.74 ? 71  ASN A CB  1 
ATOM   490  C CG  . ASN A 1 71  ? 1.879   -20.523 -31.705 1.00 33.19 ? 71  ASN A CG  1 
ATOM   491  O OD1 . ASN A 1 71  ? 2.563   -20.060 -32.621 1.00 34.73 ? 71  ASN A OD1 1 
ATOM   492  N ND2 . ASN A 1 71  ? 2.337   -21.455 -30.876 1.00 29.03 ? 71  ASN A ND2 1 
ATOM   493  N N   . TRP A 1 72  ? -1.854  -18.559 -33.067 1.00 26.36 ? 72  TRP A N   1 
ATOM   494  C CA  . TRP A 1 72  ? -3.313  -18.463 -33.295 1.00 26.82 ? 72  TRP A CA  1 
ATOM   495  C C   . TRP A 1 72  ? -3.959  -19.827 -33.054 1.00 26.51 ? 72  TRP A C   1 
ATOM   496  O O   . TRP A 1 72  ? -3.450  -20.826 -33.633 1.00 24.57 ? 72  TRP A O   1 
ATOM   497  C CB  . TRP A 1 72  ? -3.573  -17.988 -34.724 1.00 28.28 ? 72  TRP A CB  1 
ATOM   498  C CG  . TRP A 1 72  ? -2.956  -16.665 -35.042 1.00 26.88 ? 72  TRP A CG  1 
ATOM   499  C CD1 . TRP A 1 72  ? -1.757  -16.417 -35.643 1.00 27.90 ? 72  TRP A CD1 1 
ATOM   500  C CD2 . TRP A 1 72  ? -3.541  -15.394 -34.752 1.00 26.12 ? 72  TRP A CD2 1 
ATOM   501  N NE1 . TRP A 1 72  ? -1.562  -15.065 -35.746 1.00 28.38 ? 72  TRP A NE1 1 
ATOM   502  C CE2 . TRP A 1 72  ? -2.650  -14.417 -35.232 1.00 26.60 ? 72  TRP A CE2 1 
ATOM   503  C CE3 . TRP A 1 72  ? -4.737  -15.002 -34.147 1.00 26.49 ? 72  TRP A CE3 1 
ATOM   504  C CZ2 . TRP A 1 72  ? -2.911  -13.062 -35.099 1.00 28.96 ? 72  TRP A CZ2 1 
ATOM   505  C CZ3 . TRP A 1 72  ? -5.004  -13.659 -34.033 1.00 28.05 ? 72  TRP A CZ3 1 
ATOM   506  C CH2 . TRP A 1 72  ? -4.098  -12.709 -34.492 1.00 29.62 ? 72  TRP A CH2 1 
ATOM   507  N N   . ALA A 1 73  ? -5.071  -19.882 -32.305 1.00 27.55 ? 73  ALA A N   1 
ATOM   508  C CA  . ALA A 1 73  ? -5.876  -21.127 -32.205 1.00 27.34 ? 73  ALA A CA  1 
ATOM   509  C C   . ALA A 1 73  ? -6.440  -21.391 -33.594 1.00 26.85 ? 73  ALA A C   1 
ATOM   510  O O   . ALA A 1 73  ? -7.010  -20.453 -34.196 1.00 27.41 ? 73  ALA A O   1 
ATOM   511  C CB  . ALA A 1 73  ? -6.956  -21.045 -31.165 1.00 28.76 ? 73  ALA A CB  1 
ATOM   512  N N   . SER A 1 74  ? -6.244  -22.608 -34.077 1.00 27.43 ? 74  SER A N   1 
ATOM   513  C CA  . SER A 1 74  ? -6.450  -23.013 -35.481 1.00 30.95 ? 74  SER A CA  1 
ATOM   514  C C   . SER A 1 74  ? -6.871  -24.474 -35.517 1.00 31.03 ? 74  SER A C   1 
ATOM   515  O O   . SER A 1 74  ? -6.351  -25.241 -34.677 1.00 33.30 ? 74  SER A O   1 
ATOM   516  C CB  . SER A 1 74  ? -5.182  -22.805 -36.271 1.00 34.02 ? 74  SER A CB  1 
ATOM   517  O OG  . SER A 1 74  ? -5.289  -23.457 -37.522 1.00 38.02 ? 74  SER A OG  1 
ATOM   518  N N   . VAL A 1 75  ? -7.744  -24.844 -36.458 1.00 31.03 ? 75  VAL A N   1 
ATOM   519  C CA  . VAL A 1 75  ? -7.967  -26.278 -36.816 1.00 33.32 ? 75  VAL A CA  1 
ATOM   520  C C   . VAL A 1 75  ? -6.745  -26.782 -37.597 1.00 30.43 ? 75  VAL A C   1 
ATOM   521  O O   . VAL A 1 75  ? -6.216  -26.056 -38.446 1.00 31.65 ? 75  VAL A O   1 
ATOM   522  C CB  . VAL A 1 75  ? -9.290  -26.542 -37.563 1.00 33.53 ? 75  VAL A CB  1 
ATOM   523  C CG1 . VAL A 1 75  ? -9.404  -25.757 -38.844 1.00 32.58 ? 75  VAL A CG1 1 
ATOM   524  C CG2 . VAL A 1 75  ? -9.471  -28.039 -37.821 1.00 35.67 ? 75  VAL A CG2 1 
ATOM   525  N N   . SER A 1 76  ? -6.270  -27.966 -37.242 1.00 29.86 ? 76  SER A N   1 
ATOM   526  C CA  . SER A 1 76  ? -5.148  -28.664 -37.914 1.00 31.91 ? 76  SER A CA  1 
ATOM   527  C C   . SER A 1 76  ? -5.604  -30.084 -38.299 1.00 29.54 ? 76  SER A C   1 
ATOM   528  O O   . SER A 1 76  ? -6.818  -30.385 -38.296 1.00 28.18 ? 76  SER A O   1 
ATOM   529  C CB  . SER A 1 76  ? -3.909  -28.632 -37.019 1.00 32.54 ? 76  SER A CB  1 
ATOM   530  O OG  . SER A 1 76  ? -2.774  -29.186 -37.682 1.00 33.56 ? 76  SER A OG  1 
ATOM   531  N N   . ARG A 1 77  ? -4.665  -30.928 -38.663 1.00 30.20 ? 77  ARG A N   1 
ATOM   532  C CA  . ARG A 1 77  ? -4.945  -32.291 -39.164 1.00 34.24 ? 77  ARG A CA  1 
ATOM   533  C C   . ARG A 1 77  ? -5.767  -33.049 -38.118 1.00 33.19 ? 77  ARG A C   1 
ATOM   534  O O   . ARG A 1 77  ? -5.541  -32.847 -36.905 1.00 31.38 ? 77  ARG A O   1 
ATOM   535  C CB  . ARG A 1 77  ? -3.607  -32.941 -39.537 1.00 36.20 ? 77  ARG A CB  1 
ATOM   536  C CG  . ARG A 1 77  ? -3.072  -32.419 -40.862 1.00 39.63 ? 77  ARG A CG  1 
ATOM   537  C CD  . ARG A 1 77  ? -1.654  -32.881 -41.052 1.00 45.94 ? 77  ARG A CD  1 
ATOM   538  N NE  . ARG A 1 77  ? -1.027  -32.377 -42.260 1.00 50.71 ? 77  ARG A NE  1 
ATOM   539  C CZ  . ARG A 1 77  ? -1.334  -32.744 -43.505 1.00 54.09 ? 77  ARG A CZ  1 
ATOM   540  N NH1 . ARG A 1 77  ? -2.323  -33.593 -43.761 1.00 50.37 ? 77  ARG A NH1 1 
ATOM   541  N NH2 . ARG A 1 77  ? -0.654  -32.207 -44.501 1.00 55.25 ? 77  ARG A NH2 1 
ATOM   542  N N   . GLY A 1 78  ? -6.713  -33.858 -38.593 1.00 32.63 ? 78  GLY A N   1 
ATOM   543  C CA  . GLY A 1 78  ? -7.560  -34.733 -37.765 1.00 33.65 ? 78  GLY A CA  1 
ATOM   544  C C   . GLY A 1 78  ? -8.443  -33.960 -36.810 1.00 33.04 ? 78  GLY A C   1 
ATOM   545  O O   . GLY A 1 78  ? -8.771  -34.506 -35.766 1.00 32.58 ? 78  GLY A O   1 
ATOM   546  N N   . ASN A 1 79  ? -8.820  -32.729 -37.141 1.00 35.05 ? 79  ASN A N   1 
ATOM   547  C CA  . ASN A 1 79  ? -9.744  -31.920 -36.302 1.00 39.86 ? 79  ASN A CA  1 
ATOM   548  C C   . ASN A 1 79  ? -9.117  -31.630 -34.930 1.00 39.02 ? 79  ASN A C   1 
ATOM   549  O O   . ASN A 1 79  ? -9.867  -31.470 -33.963 1.00 38.19 ? 79  ASN A O   1 
ATOM   550  C CB  . ASN A 1 79  ? -11.093 -32.624 -36.122 1.00 44.04 ? 79  ASN A CB  1 
ATOM   551  C CG  . ASN A 1 79  ? -11.983 -32.516 -37.343 1.00 47.37 ? 79  ASN A CG  1 
ATOM   552  O OD1 . ASN A 1 79  ? -11.680 -31.777 -38.284 1.00 41.51 ? 79  ASN A OD1 1 
ATOM   553  N ND2 . ASN A 1 79  ? -13.093 -33.238 -37.316 1.00 49.88 ? 79  ASN A ND2 1 
ATOM   554  N N   . THR A 1 80  ? -7.792  -31.600 -34.838 1.00 34.76 ? 80  THR A N   1 
ATOM   555  C CA  . THR A 1 80  ? -7.060  -31.196 -33.615 1.00 33.52 ? 80  THR A CA  1 
ATOM   556  C C   . THR A 1 80  ? -7.010  -29.657 -33.610 1.00 33.15 ? 80  THR A C   1 
ATOM   557  O O   . THR A 1 80  ? -6.862  -29.059 -34.686 1.00 32.19 ? 80  THR A O   1 
ATOM   558  C CB  . THR A 1 80  ? -5.704  -31.924 -33.565 1.00 32.39 ? 80  THR A CB  1 
ATOM   559  O OG1 . THR A 1 80  ? -5.918  -33.339 -33.568 1.00 31.58 ? 80  THR A OG1 1 
ATOM   560  C CG2 . THR A 1 80  ? -4.891  -31.568 -32.345 1.00 33.90 ? 80  THR A CG2 1 
ATOM   561  N N   . VAL A 1 81  ? -7.180  -29.024 -32.451 1.00 33.57 ? 81  VAL A N   1 
ATOM   562  C CA  . VAL A 1 81  ? -7.005  -27.547 -32.315 1.00 32.17 ? 81  VAL A CA  1 
ATOM   563  C C   . VAL A 1 81  ? -5.565  -27.279 -31.863 1.00 28.50 ? 81  VAL A C   1 
ATOM   564  O O   . VAL A 1 81  ? -5.203  -27.728 -30.790 1.00 29.85 ? 81  VAL A O   1 
ATOM   565  C CB  . VAL A 1 81  ? -8.051  -26.958 -31.361 1.00 32.65 ? 81  VAL A CB  1 
ATOM   566  C CG1 . VAL A 1 81  ? -8.007  -25.450 -31.383 1.00 34.40 ? 81  VAL A CG1 1 
ATOM   567  C CG2 . VAL A 1 81  ? -9.449  -27.461 -31.695 1.00 32.90 ? 81  VAL A CG2 1 
ATOM   568  N N   . LEU A 1 82  ? -4.766  -26.622 -32.699 1.00 30.22 ? 82  LEU A N   1 
ATOM   569  C CA  . LEU A 1 82  ? -3.361  -26.220 -32.426 1.00 30.29 ? 82  LEU A CA  1 
ATOM   570  C C   . LEU A 1 82  ? -3.242  -24.699 -32.304 1.00 29.74 ? 82  LEU A C   1 
ATOM   571  O O   . LEU A 1 82  ? -4.094  -23.978 -32.812 1.00 26.29 ? 82  LEU A O   1 
ATOM   572  C CB  . LEU A 1 82  ? -2.492  -26.674 -33.596 1.00 32.19 ? 82  LEU A CB  1 
ATOM   573  C CG  . LEU A 1 82  ? -2.364  -28.179 -33.768 1.00 31.85 ? 82  LEU A CG  1 
ATOM   574  C CD1 . LEU A 1 82  ? -1.260  -28.486 -34.752 1.00 34.93 ? 82  LEU A CD1 1 
ATOM   575  C CD2 . LEU A 1 82  ? -2.061  -28.832 -32.448 1.00 33.70 ? 82  LEU A CD2 1 
ATOM   576  N N   . GLY A 1 83  ? -2.148  -24.255 -31.698 1.00 28.11 ? 83  GLY A N   1 
ATOM   577  C CA  . GLY A 1 83  ? -1.596  -22.913 -31.916 1.00 30.46 ? 83  GLY A CA  1 
ATOM   578  C C   . GLY A 1 83  ? -0.702  -22.903 -33.138 1.00 31.16 ? 83  GLY A C   1 
ATOM   579  O O   . GLY A 1 83  ? 0.205   -23.749 -33.192 1.00 35.10 ? 83  GLY A O   1 
ATOM   580  N N   . VAL A 1 84  ? -0.942  -22.009 -34.099 1.00 30.86 ? 84  VAL A N   1 
ATOM   581  C CA  . VAL A 1 84  ? -0.072  -21.895 -35.308 1.00 31.56 ? 84  VAL A CA  1 
ATOM   582  C C   . VAL A 1 84  ? 0.451   -20.467 -35.371 1.00 33.01 ? 84  VAL A C   1 
ATOM   583  O O   . VAL A 1 84  ? -0.325  -19.541 -35.162 1.00 35.95 ? 84  VAL A O   1 
ATOM   584  C CB  . VAL A 1 84  ? -0.775  -22.317 -36.607 1.00 29.73 ? 84  VAL A CB  1 
ATOM   585  C CG1 . VAL A 1 84  ? -1.212  -23.769 -36.532 1.00 31.61 ? 84  VAL A CG1 1 
ATOM   586  C CG2 . VAL A 1 84  ? -1.947  -21.429 -36.963 1.00 30.82 ? 84  VAL A CG2 1 
ATOM   587  N N   . SER A 1 85  ? 1.754   -20.345 -35.575 1.00 35.54 ? 85  SER A N   1 
ATOM   588  C CA  . SER A 1 85  ? 2.502   -19.073 -35.731 1.00 34.38 ? 85  SER A CA  1 
ATOM   589  C C   . SER A 1 85  ? 1.936   -18.220 -36.868 1.00 29.56 ? 85  SER A C   1 
ATOM   590  O O   . SER A 1 85  ? 1.977   -17.043 -36.738 1.00 28.63 ? 85  SER A O   1 
ATOM   591  C CB  . SER A 1 85  ? 3.936   -19.425 -35.965 1.00 39.17 ? 85  SER A CB  1 
ATOM   592  O OG  . SER A 1 85  ? 4.037   -20.830 -36.219 1.00 40.32 ? 85  SER A OG  1 
ATOM   593  N N   . GLU A 1 86  ? 1.412   -18.797 -37.943 1.00 31.39 ? 86  GLU A N   1 
ATOM   594  C CA  . GLU A 1 86  ? 0.979   -18.033 -39.144 1.00 34.85 ? 86  GLU A CA  1 
ATOM   595  C C   . GLU A 1 86  ? -0.549  -17.980 -39.197 1.00 34.45 ? 86  GLU A C   1 
ATOM   596  O O   . GLU A 1 86  ? -1.207  -19.047 -39.091 1.00 34.27 ? 86  GLU A O   1 
ATOM   597  C CB  . GLU A 1 86  ? 1.506   -18.651 -40.439 1.00 37.73 ? 86  GLU A CB  1 
ATOM   598  C CG  . GLU A 1 86  ? 2.937   -19.143 -40.336 1.00 44.78 ? 86  GLU A CG  1 
ATOM   599  C CD  . GLU A 1 86  ? 3.828   -18.882 -41.553 1.00 58.86 ? 86  GLU A CD  1 
ATOM   600  O OE1 . GLU A 1 86  ? 5.025   -19.300 -41.495 1.00 59.75 ? 86  GLU A OE1 1 
ATOM   601  O OE2 . GLU A 1 86  ? 3.345   -18.249 -42.559 1.00 57.39 ? 86  GLU A OE2 1 
ATOM   602  N N   . PHE A 1 87  ? -1.101  -16.779 -39.350 1.00 32.86 ? 87  PHE A N   1 
ATOM   603  C CA  . PHE A 1 87  ? -2.566  -16.583 -39.358 1.00 33.21 ? 87  PHE A CA  1 
ATOM   604  C C   . PHE A 1 87  ? -3.094  -17.091 -40.687 1.00 34.54 ? 87  PHE A C   1 
ATOM   605  O O   . PHE A 1 87  ? -2.434  -16.961 -41.721 1.00 37.84 ? 87  PHE A O   1 
ATOM   606  C CB  . PHE A 1 87  ? -2.979  -15.130 -39.127 1.00 30.59 ? 87  PHE A CB  1 
ATOM   607  C CG  . PHE A 1 87  ? -4.472  -14.933 -39.134 1.00 26.83 ? 87  PHE A CG  1 
ATOM   608  C CD1 . PHE A 1 87  ? -5.246  -15.371 -38.080 1.00 27.12 ? 87  PHE A CD1 1 
ATOM   609  C CD2 . PHE A 1 87  ? -5.103  -14.373 -40.223 1.00 27.19 ? 87  PHE A CD2 1 
ATOM   610  C CE1 . PHE A 1 87  ? -6.614  -15.167 -38.072 1.00 29.63 ? 87  PHE A CE1 1 
ATOM   611  C CE2 . PHE A 1 87  ? -6.470  -14.174 -40.223 1.00 28.38 ? 87  PHE A CE2 1 
ATOM   612  C CZ  . PHE A 1 87  ? -7.228  -14.582 -39.149 1.00 30.57 ? 87  PHE A CZ  1 
ATOM   613  N N   . ASP A 1 88  ? -4.265  -17.700 -40.640 1.00 35.35 ? 88  ASP A N   1 
ATOM   614  C CA  . ASP A 1 88  ? -4.948  -18.184 -41.856 1.00 36.17 ? 88  ASP A CA  1 
ATOM   615  C C   . ASP A 1 88  ? -6.442  -18.103 -41.561 1.00 34.08 ? 88  ASP A C   1 
ATOM   616  O O   . ASP A 1 88  ? -6.927  -18.923 -40.773 1.00 33.95 ? 88  ASP A O   1 
ATOM   617  C CB  . ASP A 1 88  ? -4.423  -19.561 -42.277 1.00 37.44 ? 88  ASP A CB  1 
ATOM   618  C CG  . ASP A 1 88  ? -5.029  -20.058 -43.575 1.00 41.58 ? 88  ASP A CG  1 
ATOM   619  O OD1 . ASP A 1 88  ? -6.082  -19.503 -43.976 1.00 44.16 ? 88  ASP A OD1 1 
ATOM   620  O OD2 . ASP A 1 88  ? -4.464  -21.000 -44.170 1.00 47.37 ? 88  ASP A OD2 1 
ATOM   621  N N   . GLY A 1 89  ? -7.100  -17.126 -42.183 1.00 33.41 ? 89  GLY A N   1 
ATOM   622  C CA  . GLY A 1 89  ? -8.554  -16.888 -42.148 1.00 35.30 ? 89  GLY A CA  1 
ATOM   623  C C   . GLY A 1 89  ? -9.369  -18.152 -42.312 1.00 35.14 ? 89  GLY A C   1 
ATOM   624  O O   . GLY A 1 89  ? -10.476 -18.179 -41.772 1.00 41.16 ? 89  GLY A O   1 
ATOM   625  N N   . GLN A 1 90  ? -8.843  -19.167 -43.001 1.00 38.36 ? 90  GLN A N   1 
ATOM   626  C CA  . GLN A 1 90  ? -9.563  -20.440 -43.276 1.00 44.03 ? 90  GLN A CA  1 
ATOM   627  C C   . GLN A 1 90  ? -9.529  -21.381 -42.062 1.00 40.28 ? 90  GLN A C   1 
ATOM   628  O O   . GLN A 1 90  ? -10.423 -22.206 -41.956 1.00 40.24 ? 90  GLN A O   1 
ATOM   629  C CB  . GLN A 1 90  ? -8.929  -21.166 -44.469 1.00 52.84 ? 90  GLN A CB  1 
ATOM   630  C CG  . GLN A 1 90  ? -9.233  -20.548 -45.829 1.00 57.70 ? 90  GLN A CG  1 
ATOM   631  C CD  . GLN A 1 90  ? -10.541 -21.048 -46.396 1.00 65.33 ? 90  GLN A CD  1 
ATOM   632  O OE1 . GLN A 1 90  ? -10.579 -21.973 -47.212 1.00 64.24 ? 90  GLN A OE1 1 
ATOM   633  N NE2 . GLN A 1 90  ? -11.628 -20.435 -45.958 1.00 60.73 ? 90  GLN A NE2 1 
ATOM   634  N N   . THR A 1 91  ? -8.481  -21.335 -41.246 1.00 36.46 ? 91  THR A N   1 
ATOM   635  C CA  . THR A 1 91  ? -8.240  -22.300 -40.151 1.00 33.92 ? 91  THR A CA  1 
ATOM   636  C C   . THR A 1 91  ? -8.395  -21.587 -38.788 1.00 34.58 ? 91  THR A C   1 
ATOM   637  O O   . THR A 1 91  ? -8.635  -22.287 -37.795 1.00 29.12 ? 91  THR A O   1 
ATOM   638  C CB  . THR A 1 91  ? -6.874  -22.995 -40.328 1.00 34.14 ? 91  THR A CB  1 
ATOM   639  O OG1 . THR A 1 91  ? -5.866  -21.991 -40.287 1.00 34.08 ? 91  THR A OG1 1 
ATOM   640  C CG2 . THR A 1 91  ? -6.730  -23.786 -41.616 1.00 29.81 ? 91  THR A CG2 1 
ATOM   641  N N   . CYS A 1 92  ? -8.288  -20.253 -38.724 1.00 32.66 ? 92  CYS A N   1 
ATOM   642  C CA  . CYS A 1 92  ? -8.093  -19.492 -37.458 1.00 29.66 ? 92  CYS A CA  1 
ATOM   643  C C   . CYS A 1 92  ? -9.340  -18.683 -37.081 1.00 29.81 ? 92  CYS A C   1 
ATOM   644  O O   . CYS A 1 92  ? -9.290  -17.941 -36.097 1.00 31.42 ? 92  CYS A O   1 
ATOM   645  C CB  . CYS A 1 92  ? -6.894  -18.574 -37.584 1.00 30.46 ? 92  CYS A CB  1 
ATOM   646  S SG  . CYS A 1 92  ? -5.349  -19.482 -37.822 1.00 33.70 ? 92  CYS A SG  1 
ATOM   647  N N   . LYS A 1 93  ? -10.421 -18.817 -37.838 1.00 30.61 ? 93  LYS A N   1 
ATOM   648  C CA  . LYS A 1 93  ? -11.672 -18.077 -37.585 1.00 31.65 ? 93  LYS A CA  1 
ATOM   649  C C   . LYS A 1 93  ? -12.582 -18.950 -36.729 1.00 28.46 ? 93  LYS A C   1 
ATOM   650  O O   . LYS A 1 93  ? -12.717 -20.115 -37.040 1.00 27.64 ? 93  LYS A O   1 
ATOM   651  C CB  . LYS A 1 93  ? -12.368 -17.685 -38.884 1.00 31.93 ? 93  LYS A CB  1 
ATOM   652  C CG  . LYS A 1 93  ? -13.277 -16.474 -38.710 1.00 37.26 ? 93  LYS A CG  1 
ATOM   653  C CD  . LYS A 1 93  ? -14.608 -16.541 -39.413 1.00 38.05 ? 93  LYS A CD  1 
ATOM   654  C CE  . LYS A 1 93  ? -14.524 -17.036 -40.834 1.00 39.36 ? 93  LYS A CE  1 
ATOM   655  N NZ  . LYS A 1 93  ? -15.858 -17.002 -41.461 1.00 45.51 ? 93  LYS A NZ  1 
ATOM   656  N N   . TRP A 1 94  ? -13.196 -18.395 -35.692 1.00 26.02 ? 94  TRP A N   1 
ATOM   657  C CA  . TRP A 1 94  ? -14.142 -19.180 -34.862 1.00 26.51 ? 94  TRP A CA  1 
ATOM   658  C C   . TRP A 1 94  ? -15.472 -18.461 -34.694 1.00 27.69 ? 94  TRP A C   1 
ATOM   659  O O   . TRP A 1 94  ? -15.490 -17.188 -34.617 1.00 28.44 ? 94  TRP A O   1 
ATOM   660  C CB  . TRP A 1 94  ? -13.516 -19.534 -33.504 1.00 25.35 ? 94  TRP A CB  1 
ATOM   661  C CG  . TRP A 1 94  ? -12.211 -20.249 -33.643 1.00 24.41 ? 94  TRP A CG  1 
ATOM   662  C CD1 . TRP A 1 94  ? -10.964 -19.702 -33.611 1.00 23.91 ? 94  TRP A CD1 1 
ATOM   663  C CD2 . TRP A 1 94  ? -12.036 -21.654 -33.853 1.00 26.04 ? 94  TRP A CD2 1 
ATOM   664  N NE1 . TRP A 1 94  ? -10.025 -20.670 -33.825 1.00 27.14 ? 94  TRP A NE1 1 
ATOM   665  C CE2 . TRP A 1 94  ? -10.644 -21.877 -33.978 1.00 26.83 ? 94  TRP A CE2 1 
ATOM   666  C CE3 . TRP A 1 94  ? -12.914 -22.739 -33.977 1.00 27.01 ? 94  TRP A CE3 1 
ATOM   667  C CZ2 . TRP A 1 94  ? -10.111 -23.146 -34.183 1.00 26.61 ? 94  TRP A CZ2 1 
ATOM   668  C CZ3 . TRP A 1 94  ? -12.390 -23.999 -34.204 1.00 25.48 ? 94  TRP A CZ3 1 
ATOM   669  C CH2 . TRP A 1 94  ? -11.005 -24.190 -34.305 1.00 28.10 ? 94  TRP A CH2 1 
ATOM   670  N N   . SER A 1 95  ? -16.539 -19.252 -34.578 1.00 27.09 ? 95  SER A N   1 
ATOM   671  C CA  . SER A 1 95  ? -17.802 -18.805 -33.955 1.00 29.60 ? 95  SER A CA  1 
ATOM   672  C C   . SER A 1 95  ? -17.724 -19.077 -32.460 1.00 33.54 ? 95  SER A C   1 
ATOM   673  O O   . SER A 1 95  ? -17.390 -20.228 -32.068 1.00 34.31 ? 95  SER A O   1 
ATOM   674  C CB  . SER A 1 95  ? -18.997 -19.463 -34.552 1.00 32.24 ? 95  SER A CB  1 
ATOM   675  O OG  . SER A 1 95  ? -19.015 -19.227 -35.939 1.00 35.72 ? 95  SER A OG  1 
ATOM   676  N N   . ILE A 1 96  ? -18.014 -18.054 -31.659 1.00 32.92 ? 96  ILE A N   1 
ATOM   677  C CA  . ILE A 1 96  ? -18.198 -18.216 -30.198 1.00 34.41 ? 96  ILE A CA  1 
ATOM   678  C C   . ILE A 1 96  ? -19.689 -17.980 -29.924 1.00 34.94 ? 96  ILE A C   1 
ATOM   679  O O   . ILE A 1 96  ? -20.181 -16.918 -30.262 1.00 38.45 ? 96  ILE A O   1 
ATOM   680  C CB  . ILE A 1 96  ? -17.222 -17.309 -29.433 1.00 32.57 ? 96  ILE A CB  1 
ATOM   681  C CG1 . ILE A 1 96  ? -15.805 -17.429 -30.016 1.00 32.20 ? 96  ILE A CG1 1 
ATOM   682  C CG2 . ILE A 1 96  ? -17.255 -17.629 -27.942 1.00 35.20 ? 96  ILE A CG2 1 
ATOM   683  C CD1 . ILE A 1 96  ? -14.754 -16.595 -29.294 1.00 29.79 ? 96  ILE A CD1 1 
ATOM   684  N N   . GLU A 1 97  ? -20.407 -19.003 -29.462 1.00 38.43 ? 97  GLU A N   1 
ATOM   685  C CA  . GLU A 1 97  ? -21.886 -18.968 -29.292 1.00 40.20 ? 97  GLU A CA  1 
ATOM   686  C C   . GLU A 1 97  ? -22.238 -19.236 -27.829 1.00 36.62 ? 97  GLU A C   1 
ATOM   687  O O   . GLU A 1 97  ? -21.705 -20.192 -27.263 1.00 33.57 ? 97  GLU A O   1 
ATOM   688  C CB  . GLU A 1 97  ? -22.549 -19.970 -30.239 1.00 43.61 ? 97  GLU A CB  1 
ATOM   689  C CG  . GLU A 1 97  ? -22.572 -19.502 -31.684 1.00 42.13 ? 97  GLU A CG  1 
ATOM   690  C CD  . GLU A 1 97  ? -23.009 -20.535 -32.713 1.00 43.64 ? 97  GLU A CD  1 
ATOM   691  O OE1 . GLU A 1 97  ? -22.718 -20.326 -33.903 1.00 43.71 ? 97  GLU A OE1 1 
ATOM   692  O OE2 . GLU A 1 97  ? -23.656 -21.534 -32.334 1.00 45.78 ? 97  GLU A OE2 1 
ATOM   693  N N   . TYR A 1 98  ? -23.098 -18.393 -27.254 1.00 43.16 ? 98  TYR A N   1 
ATOM   694  C CA  . TYR A 1 98  ? -23.561 -18.490 -25.845 1.00 44.96 ? 98  TYR A CA  1 
ATOM   695  C C   . TYR A 1 98  ? -24.296 -19.823 -25.691 1.00 42.93 ? 98  TYR A C   1 
ATOM   696  O O   . TYR A 1 98  ? -25.108 -20.141 -26.545 1.00 40.94 ? 98  TYR A O   1 
ATOM   697  C CB  . TYR A 1 98  ? -24.427 -17.284 -25.458 1.00 45.20 ? 98  TYR A CB  1 
ATOM   698  C CG  . TYR A 1 98  ? -25.022 -17.365 -24.068 1.00 45.23 ? 98  TYR A CG  1 
ATOM   699  C CD1 . TYR A 1 98  ? -24.211 -17.406 -22.946 1.00 44.99 ? 98  TYR A CD1 1 
ATOM   700  C CD2 . TYR A 1 98  ? -26.398 -17.406 -23.868 1.00 50.47 ? 98  TYR A CD2 1 
ATOM   701  C CE1 . TYR A 1 98  ? -24.743 -17.489 -21.672 1.00 47.40 ? 98  TYR A CE1 1 
ATOM   702  C CE2 . TYR A 1 98  ? -26.954 -17.497 -22.599 1.00 47.20 ? 98  TYR A CE2 1 
ATOM   703  C CZ  . TYR A 1 98  ? -26.118 -17.536 -21.498 1.00 52.12 ? 98  TYR A CZ  1 
ATOM   704  O OH  . TYR A 1 98  ? -26.655 -17.639 -20.249 1.00 58.05 ? 98  TYR A OH  1 
ATOM   705  N N   . SER A 1 99  ? -24.024 -20.569 -24.624 1.00 49.32 ? 99  SER A N   1 
ATOM   706  C CA  . SER A 1 99  ? -24.564 -21.937 -24.411 1.00 56.85 ? 99  SER A CA  1 
ATOM   707  C C   . SER A 1 99  ? -25.962 -21.878 -23.782 1.00 60.65 ? 99  SER A C   1 
ATOM   708  O O   . SER A 1 99  ? -26.699 -22.887 -23.886 1.00 54.41 ? 99  SER A O   1 
ATOM   709  C CB  . SER A 1 99  ? -23.662 -22.719 -23.542 1.00 57.20 ? 99  SER A CB  1 
ATOM   710  O OG  . SER A 1 99  ? -23.939 -22.394 -22.184 1.00 66.94 ? 99  SER A OG  1 
ATOM   711  N N   . GLY A 1 100 ? -26.274 -20.774 -23.098 1.00 64.42 ? 100 GLY A N   1 
ATOM   712  C CA  . GLY A 1 100 ? -27.510 -20.611 -22.308 1.00 74.31 ? 100 GLY A CA  1 
ATOM   713  C C   . GLY A 1 100 ? -27.276 -20.790 -20.812 1.00 74.11 ? 100 GLY A C   1 
ATOM   714  O O   . GLY A 1 100 ? -28.188 -20.422 -20.019 1.00 77.11 ? 100 GLY A O   1 
ATOM   715  N N   . ASN A 1 101 ? -26.121 -21.347 -20.425 1.00 69.89 ? 101 ASN A N   1 
ATOM   716  C CA  . ASN A 1 101 ? -25.797 -21.676 -19.008 1.00 69.78 ? 101 ASN A CA  1 
ATOM   717  C C   . ASN A 1 101 ? -24.762 -20.671 -18.515 1.00 65.81 ? 101 ASN A C   1 
ATOM   718  O O   . ASN A 1 101 ? -23.770 -20.476 -19.238 1.00 66.93 ? 101 ASN A O   1 
ATOM   719  C CB  . ASN A 1 101 ? -25.304 -23.119 -18.843 1.00 68.45 ? 101 ASN A CB  1 
ATOM   720  C CG  . ASN A 1 101 ? -25.494 -23.684 -17.449 1.00 64.85 ? 101 ASN A CG  1 
ATOM   721  O OD1 . ASN A 1 101 ? -25.983 -22.997 -16.549 1.00 56.16 ? 101 ASN A OD1 1 
ATOM   722  N ND2 . ASN A 1 101 ? -25.131 -24.948 -17.271 1.00 67.53 ? 101 ASN A ND2 1 
ATOM   723  N N   . GLY A 1 102 ? -25.017 -20.044 -17.360 1.00 63.86 ? 102 GLY A N   1 
ATOM   724  C CA  . GLY A 1 102 ? -24.205 -18.943 -16.805 1.00 58.57 ? 102 GLY A CA  1 
ATOM   725  C C   . GLY A 1 102 ? -23.510 -18.160 -17.908 1.00 59.35 ? 102 GLY A C   1 
ATOM   726  O O   . GLY A 1 102 ? -24.224 -17.525 -18.724 1.00 60.38 ? 102 GLY A O   1 
ATOM   727  N N   . GLU A 1 103 ? -22.173 -18.229 -17.946 1.00 58.15 ? 103 GLU A N   1 
ATOM   728  C CA  . GLU A 1 103 ? -21.283 -17.509 -18.908 1.00 54.29 ? 103 GLU A CA  1 
ATOM   729  C C   . GLU A 1 103 ? -20.536 -18.551 -19.764 1.00 45.61 ? 103 GLU A C   1 
ATOM   730  O O   . GLU A 1 103 ? -19.313 -18.449 -19.906 1.00 42.66 ? 103 GLU A O   1 
ATOM   731  C CB  . GLU A 1 103 ? -20.322 -16.606 -18.125 1.00 54.06 ? 103 GLU A CB  1 
ATOM   732  C CG  . GLU A 1 103 ? -21.020 -15.620 -17.199 1.00 61.12 ? 103 GLU A CG  1 
ATOM   733  C CD  . GLU A 1 103 ? -20.229 -15.171 -15.979 1.00 68.33 ? 103 GLU A CD  1 
ATOM   734  O OE1 . GLU A 1 103 ? -19.258 -15.867 -15.604 1.00 76.11 ? 103 GLU A OE1 1 
ATOM   735  O OE2 . GLU A 1 103 ? -20.584 -14.118 -15.401 1.00 71.90 ? 103 GLU A OE2 1 
ATOM   736  N N   . GLU A 1 104 ? -21.241 -19.572 -20.258 1.00 40.81 ? 104 GLU A N   1 
ATOM   737  C CA  . GLU A 1 104 ? -20.600 -20.722 -20.935 1.00 36.90 ? 104 GLU A CA  1 
ATOM   738  C C   . GLU A 1 104 ? -20.832 -20.559 -22.425 1.00 29.99 ? 104 GLU A C   1 
ATOM   739  O O   . GLU A 1 104 ? -21.914 -20.129 -22.789 1.00 31.61 ? 104 GLU A O   1 
ATOM   740  C CB  . GLU A 1 104 ? -21.109 -22.035 -20.354 1.00 43.57 ? 104 GLU A CB  1 
ATOM   741  C CG  . GLU A 1 104 ? -20.573 -22.324 -18.961 1.00 44.63 ? 104 GLU A CG  1 
ATOM   742  C CD  . GLU A 1 104 ? -20.974 -23.681 -18.414 1.00 46.17 ? 104 GLU A CD  1 
ATOM   743  O OE1 . GLU A 1 104 ? -21.827 -24.354 -19.018 1.00 40.96 ? 104 GLU A OE1 1 
ATOM   744  O OE2 . GLU A 1 104 ? -20.405 -24.067 -17.395 1.00 52.11 ? 104 GLU A OE2 1 
ATOM   745  N N   . PHE A 1 105 ? -19.808 -20.811 -23.232 1.00 28.41 ? 105 PHE A N   1 
ATOM   746  C CA  . PHE A 1 105 ? -19.798 -20.594 -24.702 1.00 27.79 ? 105 PHE A CA  1 
ATOM   747  C C   . PHE A 1 105 ? -19.342 -21.884 -25.362 1.00 27.86 ? 105 PHE A C   1 
ATOM   748  O O   . PHE A 1 105 ? -18.708 -22.676 -24.667 1.00 25.94 ? 105 PHE A O   1 
ATOM   749  C CB  . PHE A 1 105 ? -18.861 -19.439 -25.071 1.00 29.32 ? 105 PHE A CB  1 
ATOM   750  C CG  . PHE A 1 105 ? -19.360 -18.093 -24.611 1.00 28.88 ? 105 PHE A CG  1 
ATOM   751  C CD1 . PHE A 1 105 ? -19.026 -17.597 -23.368 1.00 31.31 ? 105 PHE A CD1 1 
ATOM   752  C CD2 . PHE A 1 105 ? -20.190 -17.327 -25.418 1.00 33.29 ? 105 PHE A CD2 1 
ATOM   753  C CE1 . PHE A 1 105 ? -19.519 -16.372 -22.936 1.00 31.86 ? 105 PHE A CE1 1 
ATOM   754  C CE2 . PHE A 1 105 ? -20.682 -16.100 -24.986 1.00 33.07 ? 105 PHE A CE2 1 
ATOM   755  C CZ  . PHE A 1 105 ? -20.339 -15.623 -23.744 1.00 29.41 ? 105 PHE A CZ  1 
ATOM   756  N N   . TRP A 1 106 ? -19.701 -22.081 -26.638 1.00 31.32 ? 106 TRP A N   1 
ATOM   757  C CA  . TRP A 1 106 ? -19.146 -23.104 -27.569 1.00 29.20 ? 106 TRP A CA  1 
ATOM   758  C C   . TRP A 1 106 ? -18.252 -22.361 -28.570 1.00 27.54 ? 106 TRP A C   1 
ATOM   759  O O   . TRP A 1 106 ? -18.698 -21.339 -29.065 1.00 31.04 ? 106 TRP A O   1 
ATOM   760  C CB  . TRP A 1 106 ? -20.235 -23.898 -28.306 1.00 29.97 ? 106 TRP A CB  1 
ATOM   761  C CG  . TRP A 1 106 ? -21.169 -24.668 -27.429 1.00 31.83 ? 106 TRP A CG  1 
ATOM   762  C CD1 . TRP A 1 106 ? -20.818 -25.650 -26.562 1.00 31.29 ? 106 TRP A CD1 1 
ATOM   763  C CD2 . TRP A 1 106 ? -22.607 -24.550 -27.348 1.00 30.26 ? 106 TRP A CD2 1 
ATOM   764  N NE1 . TRP A 1 106 ? -21.920 -26.114 -25.909 1.00 31.86 ? 106 TRP A NE1 1 
ATOM   765  C CE2 . TRP A 1 106 ? -23.031 -25.451 -26.357 1.00 31.62 ? 106 TRP A CE2 1 
ATOM   766  C CE3 . TRP A 1 106 ? -23.570 -23.726 -27.949 1.00 32.36 ? 106 TRP A CE3 1 
ATOM   767  C CZ2 . TRP A 1 106 ? -24.374 -25.597 -25.998 1.00 33.36 ? 106 TRP A CZ2 1 
ATOM   768  C CZ3 . TRP A 1 106 ? -24.898 -23.857 -27.588 1.00 31.12 ? 106 TRP A CZ3 1 
ATOM   769  C CH2 . TRP A 1 106 ? -25.291 -24.784 -26.619 1.00 32.39 ? 106 TRP A CH2 1 
ATOM   770  N N   . ILE A 1 107 ? -17.017 -22.812 -28.791 1.00 27.75 ? 107 ILE A N   1 
ATOM   771  C CA  . ILE A 1 107 ? -16.098 -22.265 -29.833 1.00 27.93 ? 107 ILE A CA  1 
ATOM   772  C C   . ILE A 1 107 ? -16.212 -23.222 -31.003 1.00 27.73 ? 107 ILE A C   1 
ATOM   773  O O   . ILE A 1 107 ? -15.854 -24.388 -30.810 1.00 32.88 ? 107 ILE A O   1 
ATOM   774  C CB  . ILE A 1 107 ? -14.643 -22.101 -29.356 1.00 27.19 ? 107 ILE A CB  1 
ATOM   775  C CG1 . ILE A 1 107 ? -14.547 -21.201 -28.122 1.00 28.21 ? 107 ILE A CG1 1 
ATOM   776  C CG2 . ILE A 1 107 ? -13.789 -21.554 -30.477 1.00 27.46 ? 107 ILE A CG2 1 
ATOM   777  C CD1 . ILE A 1 107 ? -13.268 -21.343 -27.354 1.00 26.39 ? 107 ILE A CD1 1 
ATOM   778  N N   . ARG A 1 108 ? -16.760 -22.760 -32.120 1.00 25.99 ? 108 ARG A N   1 
ATOM   779  C CA  . ARG A 1 108 ? -17.113 -23.634 -33.248 1.00 29.51 ? 108 ARG A CA  1 
ATOM   780  C C   . ARG A 1 108 ? -16.397 -23.234 -34.536 1.00 31.75 ? 108 ARG A C   1 
ATOM   781  O O   . ARG A 1 108 ? -16.157 -22.018 -34.744 1.00 27.69 ? 108 ARG A O   1 
ATOM   782  C CB  . ARG A 1 108 ? -18.601 -23.519 -33.572 1.00 33.94 ? 108 ARG A CB  1 
ATOM   783  C CG  . ARG A 1 108 ? -19.487 -23.101 -32.411 1.00 36.70 ? 108 ARG A CG  1 
ATOM   784  C CD  . ARG A 1 108 ? -20.946 -23.284 -32.780 1.00 33.82 ? 108 ARG A CD  1 
ATOM   785  N NE  . ARG A 1 108 ? -21.229 -24.625 -33.258 1.00 33.86 ? 108 ARG A NE  1 
ATOM   786  C CZ  . ARG A 1 108 ? -22.417 -25.201 -33.215 1.00 33.48 ? 108 ARG A CZ  1 
ATOM   787  N NH1 . ARG A 1 108 ? -23.453 -24.547 -32.717 1.00 31.74 ? 108 ARG A NH1 1 
ATOM   788  N NH2 . ARG A 1 108 ? -22.562 -26.433 -33.667 1.00 33.71 ? 108 ARG A NH2 1 
ATOM   789  N N   . VAL A 1 109 ? -16.229 -24.218 -35.428 1.00 33.16 ? 109 VAL A N   1 
ATOM   790  C CA  . VAL A 1 109 ? -15.899 -23.981 -36.863 1.00 39.00 ? 109 VAL A CA  1 
ATOM   791  C C   . VAL A 1 109 ? -17.005 -23.103 -37.449 1.00 38.18 ? 109 VAL A C   1 
ATOM   792  O O   . VAL A 1 109 ? -18.192 -23.404 -37.294 1.00 36.85 ? 109 VAL A O   1 
ATOM   793  C CB  . VAL A 1 109 ? -15.725 -25.281 -37.682 1.00 42.67 ? 109 VAL A CB  1 
ATOM   794  C CG1 . VAL A 1 109 ? -14.761 -25.054 -38.841 1.00 45.04 ? 109 VAL A CG1 1 
ATOM   795  C CG2 . VAL A 1 109 ? -15.262 -26.468 -36.849 1.00 41.58 ? 109 VAL A CG2 1 
ATOM   796  N N   . PRO A 1 110 ? -16.659 -21.984 -38.127 1.00 40.52 ? 110 PRO A N   1 
ATOM   797  C CA  . PRO A 1 110 ? -17.661 -21.120 -38.748 1.00 41.30 ? 110 PRO A CA  1 
ATOM   798  C C   . PRO A 1 110 ? -18.181 -21.929 -39.934 1.00 43.18 ? 110 PRO A C   1 
ATOM   799  O O   . PRO A 1 110 ? -17.365 -22.497 -40.643 1.00 44.74 ? 110 PRO A O   1 
ATOM   800  C CB  . PRO A 1 110 ? -16.933 -19.861 -39.222 1.00 39.86 ? 110 PRO A CB  1 
ATOM   801  C CG  . PRO A 1 110 ? -15.479 -20.057 -38.813 1.00 41.20 ? 110 PRO A CG  1 
ATOM   802  C CD  . PRO A 1 110 ? -15.295 -21.510 -38.400 1.00 40.38 ? 110 PRO A CD  1 
ATOM   803  N N   . ARG A 1 111 ? -19.493 -22.045 -40.072 1.00 47.29 ? 111 ARG A N   1 
ATOM   804  C CA  . ARG A 1 111 ? -20.089 -22.866 -41.157 1.00 53.42 ? 111 ARG A CA  1 
ATOM   805  C C   . ARG A 1 111 ? -21.381 -22.181 -41.602 1.00 53.39 ? 111 ARG A C   1 
ATOM   806  O O   . ARG A 1 111 ? -22.283 -21.997 -40.750 1.00 53.76 ? 111 ARG A O   1 
ATOM   807  C CB  . ARG A 1 111 ? -20.223 -24.321 -40.691 1.00 52.70 ? 111 ARG A CB  1 
ATOM   808  C CG  . ARG A 1 111 ? -21.139 -25.177 -41.546 1.00 61.99 ? 111 ARG A CG  1 
ATOM   809  C CD  . ARG A 1 111 ? -20.610 -26.566 -41.878 1.00 68.28 ? 111 ARG A CD  1 
ATOM   810  N NE  . ARG A 1 111 ? -21.613 -27.640 -41.872 1.00 71.83 ? 111 ARG A NE  1 
ATOM   811  C CZ  . ARG A 1 111 ? -22.880 -27.556 -42.301 1.00 78.54 ? 111 ARG A CZ  1 
ATOM   812  N NH1 . ARG A 1 111 ? -23.373 -26.435 -42.809 1.00 83.46 ? 111 ARG A NH1 1 
ATOM   813  N NH2 . ARG A 1 111 ? -23.661 -28.620 -42.228 1.00 77.03 ? 111 ARG A NH2 1 
ATOM   814  N N   . GLU A 1 112 ? -21.401 -21.746 -42.869 1.00 57.82 ? 112 GLU A N   1 
ATOM   815  C CA  . GLU A 1 112 ? -22.621 -21.298 -43.586 1.00 58.53 ? 112 GLU A CA  1 
ATOM   816  C C   . GLU A 1 112 ? -23.644 -22.418 -43.441 1.00 56.01 ? 112 GLU A C   1 
ATOM   817  O O   . GLU A 1 112 ? -23.360 -23.535 -43.927 1.00 56.02 ? 112 GLU A O   1 
ATOM   818  C CB  . GLU A 1 112 ? -22.322 -21.036 -45.059 1.00 61.08 ? 112 GLU A CB  1 
ATOM   819  C CG  . GLU A 1 112 ? -23.429 -20.273 -45.765 1.00 65.22 ? 112 GLU A CG  1 
ATOM   820  C CD  . GLU A 1 112 ? -23.109 -18.817 -46.060 1.00 64.54 ? 112 GLU A CD  1 
ATOM   821  O OE1 . GLU A 1 112 ? -24.047 -18.054 -46.355 1.00 58.17 ? 112 GLU A OE1 1 
ATOM   822  O OE2 . GLU A 1 112 ? -21.915 -18.455 -46.021 1.00 71.26 ? 112 GLU A OE2 1 
ATOM   823  N N   . GLY A 1 113 ? -24.731 -22.166 -42.720 1.00 55.13 ? 113 GLY A N   1 
ATOM   824  C CA  . GLY A 1 113 ? -25.713 -23.221 -42.418 1.00 50.76 ? 113 GLY A CA  1 
ATOM   825  C C   . GLY A 1 113 ? -25.741 -23.568 -40.947 1.00 56.44 ? 113 GLY A C   1 
ATOM   826  O O   . GLY A 1 113 ? -26.734 -24.213 -40.533 1.00 55.41 ? 113 GLY A O   1 
ATOM   827  N N   . GLY A 1 114 ? -24.698 -23.175 -40.192 1.00 59.99 ? 114 GLY A N   1 
ATOM   828  C CA  . GLY A 1 114 ? -24.502 -23.531 -38.768 1.00 53.69 ? 114 GLY A CA  1 
ATOM   829  C C   . GLY A 1 114 ? -24.078 -24.986 -38.576 1.00 51.35 ? 114 GLY A C   1 
ATOM   830  O O   . GLY A 1 114 ? -23.590 -25.624 -39.562 1.00 50.58 ? 114 GLY A O   1 
ATOM   831  N N   . GLY A 1 115 ? -24.229 -25.490 -37.346 1.00 46.11 ? 115 GLY A N   1 
ATOM   832  C CA  . GLY A 1 115 ? -23.870 -26.865 -36.926 1.00 46.76 ? 115 GLY A CA  1 
ATOM   833  C C   . GLY A 1 115 ? -22.377 -27.174 -37.034 1.00 42.00 ? 115 GLY A C   1 
ATOM   834  O O   . GLY A 1 115 ? -22.041 -28.344 -37.289 1.00 36.20 ? 115 GLY A O   1 
ATOM   835  N N   . GLY A 1 116 ? -21.513 -26.164 -36.885 1.00 38.05 ? 116 GLY A N   1 
ATOM   836  C CA  . GLY A 1 116 ? -20.049 -26.339 -36.859 1.00 35.76 ? 116 GLY A CA  1 
ATOM   837  C C   . GLY A 1 116 ? -19.588 -27.156 -35.651 1.00 29.40 ? 116 GLY A C   1 
ATOM   838  O O   . GLY A 1 116 ? -19.999 -26.891 -34.527 1.00 25.96 ? 116 GLY A O   1 
ATOM   839  N N   . ALA A 1 117 ? -18.728 -28.131 -35.877 1.00 28.78 ? 117 ALA A N   1 
ATOM   840  C CA  . ALA A 1 117 ? -18.070 -28.897 -34.808 1.00 29.25 ? 117 ALA A CA  1 
ATOM   841  C C   . ALA A 1 117 ? -17.415 -27.922 -33.802 1.00 29.46 ? 117 ALA A C   1 
ATOM   842  O O   . ALA A 1 117 ? -17.036 -26.788 -34.176 1.00 24.92 ? 117 ALA A O   1 
ATOM   843  C CB  . ALA A 1 117 ? -17.106 -29.873 -35.428 1.00 31.16 ? 117 ALA A CB  1 
ATOM   844  N N   . VAL A 1 118 ? -17.330 -28.331 -32.531 1.00 28.61 ? 118 VAL A N   1 
ATOM   845  C CA  . VAL A 1 118 ? -16.947 -27.410 -31.434 1.00 27.40 ? 118 VAL A CA  1 
ATOM   846  C C   . VAL A 1 118 ? -15.686 -27.917 -30.721 1.00 27.27 ? 118 VAL A C   1 
ATOM   847  O O   . VAL A 1 118 ? -15.366 -29.120 -30.813 1.00 27.60 ? 118 VAL A O   1 
ATOM   848  C CB  . VAL A 1 118 ? -18.125 -27.206 -30.476 1.00 28.20 ? 118 VAL A CB  1 
ATOM   849  C CG1 . VAL A 1 118 ? -19.334 -26.696 -31.237 1.00 33.46 ? 118 VAL A CG1 1 
ATOM   850  C CG2 . VAL A 1 118 ? -18.462 -28.453 -29.680 1.00 29.31 ? 118 VAL A CG2 1 
ATOM   851  N N   . TRP A 1 119 ? -15.013 -27.018 -30.016 1.00 24.18 ? 119 TRP A N   1 
ATOM   852  C CA  . TRP A 1 119 ? -13.913 -27.391 -29.106 1.00 26.72 ? 119 TRP A CA  1 
ATOM   853  C C   . TRP A 1 119 ? -14.462 -28.416 -28.122 1.00 28.61 ? 119 TRP A C   1 
ATOM   854  O O   . TRP A 1 119 ? -15.434 -28.086 -27.446 1.00 26.64 ? 119 TRP A O   1 
ATOM   855  C CB  . TRP A 1 119 ? -13.330 -26.176 -28.385 1.00 26.48 ? 119 TRP A CB  1 
ATOM   856  C CG  . TRP A 1 119 ? -12.495 -25.270 -29.229 1.00 25.93 ? 119 TRP A CG  1 
ATOM   857  C CD1 . TRP A 1 119 ? -12.562 -25.068 -30.576 1.00 27.42 ? 119 TRP A CD1 1 
ATOM   858  C CD2 . TRP A 1 119 ? -11.454 -24.413 -28.739 1.00 26.12 ? 119 TRP A CD2 1 
ATOM   859  N NE1 . TRP A 1 119 ? -11.636 -24.131 -30.948 1.00 27.85 ? 119 TRP A NE1 1 
ATOM   860  C CE2 . TRP A 1 119 ? -10.946 -23.716 -29.841 1.00 25.59 ? 119 TRP A CE2 1 
ATOM   861  C CE3 . TRP A 1 119 ? -10.935 -24.141 -27.470 1.00 25.88 ? 119 TRP A CE3 1 
ATOM   862  C CZ2 . TRP A 1 119 ? -9.926  -22.781 -29.710 1.00 26.28 ? 119 TRP A CZ2 1 
ATOM   863  C CZ3 . TRP A 1 119 ? -9.925  -23.224 -27.340 1.00 25.44 ? 119 TRP A CZ3 1 
ATOM   864  C CH2 . TRP A 1 119 ? -9.440  -22.542 -28.454 1.00 26.20 ? 119 TRP A CH2 1 
ATOM   865  N N   . THR A 1 120 ? -13.815 -29.589 -28.079 1.00 31.41 ? 120 THR A N   1 
ATOM   866  C CA  . THR A 1 120 ? -14.116 -30.748 -27.203 1.00 30.26 ? 120 THR A CA  1 
ATOM   867  C C   . THR A 1 120 ? -12.837 -31.134 -26.430 1.00 30.75 ? 120 THR A C   1 
ATOM   868  O O   . THR A 1 120 ? -11.833 -31.498 -27.044 1.00 30.30 ? 120 THR A O   1 
ATOM   869  C CB  . THR A 1 120 ? -14.688 -31.891 -28.043 1.00 29.24 ? 120 THR A CB  1 
ATOM   870  O OG1 . THR A 1 120 ? -15.694 -31.361 -28.919 1.00 30.19 ? 120 THR A OG1 1 
ATOM   871  C CG2 . THR A 1 120 ? -15.267 -33.001 -27.188 1.00 29.67 ? 120 THR A CG2 1 
ATOM   872  N N   . ILE A 1 121 ? -12.854 -30.980 -25.114 1.00 31.70 ? 121 ILE A N   1 
ATOM   873  C CA  . ILE A 1 121 ? -11.700 -31.303 -24.232 1.00 36.94 ? 121 ILE A CA  1 
ATOM   874  C C   . ILE A 1 121 ? -11.905 -32.754 -23.767 1.00 40.99 ? 121 ILE A C   1 
ATOM   875  O O   . ILE A 1 121 ? -12.953 -33.006 -23.159 1.00 34.29 ? 121 ILE A O   1 
ATOM   876  C CB  . ILE A 1 121 ? -11.629 -30.263 -23.095 1.00 36.52 ? 121 ILE A CB  1 
ATOM   877  C CG1 . ILE A 1 121 ? -11.285 -28.873 -23.634 1.00 36.20 ? 121 ILE A CG1 1 
ATOM   878  C CG2 . ILE A 1 121 ? -10.671 -30.690 -21.998 1.00 39.79 ? 121 ILE A CG2 1 
ATOM   879  C CD1 . ILE A 1 121 ? -12.462 -27.934 -23.785 1.00 34.06 ? 121 ILE A CD1 1 
ATOM   880  N N   . LYS A 1 122 ? -10.996 -33.679 -24.126 1.00 47.87 ? 122 LYS A N   1 
ATOM   881  C CA  . LYS A 1 122 ? -11.190 -35.157 -23.957 1.00 59.82 ? 122 LYS A CA  1 
ATOM   882  C C   . LYS A 1 122 ? -11.072 -35.548 -22.479 1.00 66.25 ? 122 LYS A C   1 
ATOM   883  O O   . LYS A 1 122 ? -10.175 -35.123 -21.756 1.00 60.82 ? 122 LYS A O   1 
ATOM   884  C CB  . LYS A 1 122 ? -10.242 -36.000 -24.828 1.00 59.59 ? 122 LYS A CB  1 
ATOM   885  C CG  . LYS A 1 122 ? -8.762  -35.682 -24.729 1.00 59.69 ? 122 LYS A CG  1 
ATOM   886  C CD  . LYS A 1 122 ? -7.809  -36.626 -25.474 1.00 67.21 ? 122 LYS A CD  1 
ATOM   887  C CE  . LYS A 1 122 ? -6.371  -36.413 -25.014 1.00 66.89 ? 122 LYS A CE  1 
ATOM   888  N NZ  . LYS A 1 122 ? -5.368  -37.081 -25.874 1.00 63.20 ? 122 LYS A NZ  1 
ATOM   889  N N   . PRO A 1 123 ? -12.002 -36.360 -21.944 1.00 70.26 ? 123 PRO A N   1 
ATOM   890  C CA  . PRO A 1 123 ? -11.913 -36.751 -20.541 1.00 72.03 ? 123 PRO A CA  1 
ATOM   891  C C   . PRO A 1 123 ? -10.659 -37.608 -20.322 1.00 61.23 ? 123 PRO A C   1 
ATOM   892  O O   . PRO A 1 123 ? -9.904  -37.171 -19.503 1.00 53.74 ? 123 PRO A O   1 
ATOM   893  C CB  . PRO A 1 123 ? -13.214 -37.521 -20.264 1.00 76.34 ? 123 PRO A CB  1 
ATOM   894  C CG  . PRO A 1 123 ? -14.103 -37.274 -21.478 1.00 75.24 ? 123 PRO A CG  1 
ATOM   895  C CD  . PRO A 1 123 ? -13.183 -36.904 -22.625 1.00 73.50 ? 123 PRO A CD  1 
ATOM   896  N N   . GLY A 1 128 ? -4.575  -34.211 -14.885 1.00 47.66 ? 128 GLY A N   1 
ATOM   897  C CA  . GLY A 1 128 ? -3.556  -34.361 -15.945 1.00 46.96 ? 128 GLY A CA  1 
ATOM   898  C C   . GLY A 1 128 ? -3.853  -33.488 -17.165 1.00 46.52 ? 128 GLY A C   1 
ATOM   899  O O   . GLY A 1 128 ? -4.926  -32.904 -17.278 1.00 49.67 ? 128 GLY A O   1 
ATOM   900  N N   . PRO A 1 129 ? -2.904  -33.365 -18.121 1.00 47.01 ? 129 PRO A N   1 
ATOM   901  C CA  . PRO A 1 129 ? -3.061  -32.510 -19.299 1.00 38.94 ? 129 PRO A CA  1 
ATOM   902  C C   . PRO A 1 129 ? -3.938  -33.174 -20.351 1.00 39.33 ? 129 PRO A C   1 
ATOM   903  O O   . PRO A 1 129 ? -3.954  -34.368 -20.378 1.00 44.08 ? 129 PRO A O   1 
ATOM   904  C CB  . PRO A 1 129 ? -1.651  -32.426 -19.874 1.00 40.40 ? 129 PRO A CB  1 
ATOM   905  C CG  . PRO A 1 129 ? -1.043  -33.763 -19.503 1.00 44.38 ? 129 PRO A CG  1 
ATOM   906  C CD  . PRO A 1 129 ? -1.607  -34.057 -18.125 1.00 47.42 ? 129 PRO A CD  1 
ATOM   907  N N   . THR A 1 130 ? -4.622  -32.392 -21.185 1.00 38.45 ? 130 THR A N   1 
ATOM   908  C CA  . THR A 1 130 ? -5.599  -32.900 -22.184 1.00 37.95 ? 130 THR A CA  1 
ATOM   909  C C   . THR A 1 130 ? -5.556  -32.045 -23.435 1.00 31.18 ? 130 THR A C   1 
ATOM   910  O O   . THR A 1 130 ? -5.415  -30.843 -23.288 1.00 36.07 ? 130 THR A O   1 
ATOM   911  C CB  . THR A 1 130 ? -7.037  -32.846 -21.661 1.00 42.31 ? 130 THR A CB  1 
ATOM   912  O OG1 . THR A 1 130 ? -7.041  -33.360 -20.340 1.00 47.46 ? 130 THR A OG1 1 
ATOM   913  C CG2 . THR A 1 130 ? -7.978  -33.694 -22.471 1.00 43.70 ? 130 THR A CG2 1 
ATOM   914  N N   . THR A 1 131 ? -5.745  -32.655 -24.596 1.00 32.50 ? 131 THR A N   1 
ATOM   915  C CA  . THR A 1 131 ? -5.799  -31.972 -25.906 1.00 32.21 ? 131 THR A CA  1 
ATOM   916  C C   . THR A 1 131 ? -7.241  -31.553 -26.231 1.00 35.71 ? 131 THR A C   1 
ATOM   917  O O   . THR A 1 131 ? -8.186  -31.858 -25.444 1.00 37.60 ? 131 THR A O   1 
ATOM   918  C CB  . THR A 1 131 ? -5.179  -32.852 -26.988 1.00 33.69 ? 131 THR A CB  1 
ATOM   919  O OG1 . THR A 1 131 ? -5.960  -34.031 -27.147 1.00 37.74 ? 131 THR A OG1 1 
ATOM   920  C CG2 . THR A 1 131 ? -3.757  -33.226 -26.659 1.00 34.50 ? 131 THR A CG2 1 
ATOM   921  N N   . VAL A 1 132 ? -7.388  -30.841 -27.343 1.00 33.02 ? 132 VAL A N   1 
ATOM   922  C CA  . VAL A 1 132 ? -8.669  -30.270 -27.812 1.00 33.14 ? 132 VAL A CA  1 
ATOM   923  C C   . VAL A 1 132 ? -8.858  -30.755 -29.242 1.00 35.22 ? 132 VAL A C   1 
ATOM   924  O O   . VAL A 1 132 ? -7.868  -30.693 -30.042 1.00 38.56 ? 132 VAL A O   1 
ATOM   925  C CB  . VAL A 1 132 ? -8.675  -28.736 -27.765 1.00 34.04 ? 132 VAL A CB  1 
ATOM   926  C CG1 . VAL A 1 132 ? -10.048 -28.176 -28.106 1.00 36.31 ? 132 VAL A CG1 1 
ATOM   927  C CG2 . VAL A 1 132 ? -8.201  -28.200 -26.447 1.00 33.56 ? 132 VAL A CG2 1 
ATOM   928  N N   . PHE A 1 133 ? -10.072 -31.209 -29.567 1.00 34.20 ? 133 PHE A N   1 
ATOM   929  C CA  . PHE A 1 133 ? -10.428 -31.588 -30.954 1.00 35.39 ? 133 PHE A CA  1 
ATOM   930  C C   . PHE A 1 133 ? -11.845 -31.105 -31.249 1.00 32.47 ? 133 PHE A C   1 
ATOM   931  O O   . PHE A 1 133 ? -12.583 -30.669 -30.359 1.00 29.80 ? 133 PHE A O   1 
ATOM   932  C CB  . PHE A 1 133 ? -10.220 -33.090 -31.162 1.00 36.80 ? 133 PHE A CB  1 
ATOM   933  C CG  . PHE A 1 133 ? -11.173 -33.934 -30.364 1.00 37.52 ? 133 PHE A CG  1 
ATOM   934  C CD1 . PHE A 1 133 ? -10.907 -34.241 -29.040 1.00 41.07 ? 133 PHE A CD1 1 
ATOM   935  C CD2 . PHE A 1 133 ? -12.362 -34.373 -30.924 1.00 35.86 ? 133 PHE A CD2 1 
ATOM   936  C CE1 . PHE A 1 133 ? -11.810 -35.002 -28.305 1.00 42.86 ? 133 PHE A CE1 1 
ATOM   937  C CE2 . PHE A 1 133 ? -13.255 -35.136 -30.190 1.00 36.02 ? 133 PHE A CE2 1 
ATOM   938  C CZ  . PHE A 1 133 ? -12.988 -35.438 -28.882 1.00 37.75 ? 133 PHE A CZ  1 
ATOM   939  N N   . LEU A 1 134 ? -12.192 -31.152 -32.522 1.00 35.59 ? 134 LEU A N   1 
ATOM   940  C CA  . LEU A 1 134 ? -13.502 -30.706 -33.039 1.00 35.99 ? 134 LEU A CA  1 
ATOM   941  C C   . LEU A 1 134 ? -14.401 -31.925 -33.110 1.00 37.38 ? 134 LEU A C   1 
ATOM   942  O O   . LEU A 1 134 ? -13.969 -32.913 -33.696 1.00 40.25 ? 134 LEU A O   1 
ATOM   943  C CB  . LEU A 1 134 ? -13.295 -30.071 -34.412 1.00 33.24 ? 134 LEU A CB  1 
ATOM   944  C CG  . LEU A 1 134 ? -12.432 -28.818 -34.392 1.00 30.71 ? 134 LEU A CG  1 
ATOM   945  C CD1 . LEU A 1 134 ? -12.336 -28.210 -35.783 1.00 28.69 ? 134 LEU A CD1 1 
ATOM   946  C CD2 . LEU A 1 134 ? -12.986 -27.823 -33.363 1.00 30.10 ? 134 LEU A CD2 1 
ATOM   947  N N   . ASP A 1 135 ? -15.583 -31.834 -32.506 1.00 41.00 ? 135 ASP A N   1 
ATOM   948  C CA  . ASP A 1 135 ? -16.640 -32.875 -32.586 1.00 35.67 ? 135 ASP A CA  1 
ATOM   949  C C   . ASP A 1 135 ? -18.014 -32.199 -32.652 1.00 35.22 ? 135 ASP A C   1 
ATOM   950  O O   . ASP A 1 135 ? -18.125 -31.007 -32.288 1.00 34.63 ? 135 ASP A O   1 
ATOM   951  C CB  . ASP A 1 135 ? -16.491 -33.865 -31.425 1.00 37.81 ? 135 ASP A CB  1 
ATOM   952  C CG  . ASP A 1 135 ? -16.853 -35.287 -31.810 1.00 32.71 ? 135 ASP A CG  1 
ATOM   953  O OD1 . ASP A 1 135 ? -16.668 -36.176 -31.013 1.00 33.75 ? 135 ASP A OD1 1 
ATOM   954  O OD2 . ASP A 1 135 ? -17.330 -35.461 -32.899 1.00 30.64 ? 135 ASP A OD2 1 
ATOM   955  N N   . LEU A 1 136 ? -19.016 -32.930 -33.148 1.00 36.33 ? 136 LEU A N   1 
ATOM   956  C CA  . LEU A 1 136 ? -20.430 -32.488 -33.192 1.00 35.27 ? 136 LEU A CA  1 
ATOM   957  C C   . LEU A 1 136 ? -20.798 -31.984 -31.803 1.00 31.43 ? 136 LEU A C   1 
ATOM   958  O O   . LEU A 1 136 ? -20.408 -32.612 -30.809 1.00 29.56 ? 136 LEU A O   1 
ATOM   959  C CB  . LEU A 1 136 ? -21.375 -33.631 -33.586 1.00 40.33 ? 136 LEU A CB  1 
ATOM   960  C CG  . LEU A 1 136 ? -21.254 -34.186 -35.008 1.00 46.07 ? 136 LEU A CG  1 
ATOM   961  C CD1 . LEU A 1 136 ? -22.574 -34.821 -35.436 1.00 53.06 ? 136 LEU A CD1 1 
ATOM   962  C CD2 . LEU A 1 136 ? -20.817 -33.129 -36.024 1.00 46.95 ? 136 LEU A CD2 1 
ATOM   963  N N   . LEU A 1 137 ? -21.511 -30.868 -31.767 1.00 28.69 ? 137 LEU A N   1 
ATOM   964  C CA  . LEU A 1 137 ? -22.020 -30.270 -30.524 1.00 31.50 ? 137 LEU A CA  1 
ATOM   965  C C   . LEU A 1 137 ? -23.047 -31.222 -29.906 1.00 34.43 ? 137 LEU A C   1 
ATOM   966  O O   . LEU A 1 137 ? -23.971 -31.675 -30.637 1.00 27.43 ? 137 LEU A O   1 
ATOM   967  C CB  . LEU A 1 137 ? -22.625 -28.894 -30.786 1.00 29.98 ? 137 LEU A CB  1 
ATOM   968  C CG  . LEU A 1 137 ? -23.424 -28.301 -29.615 1.00 32.13 ? 137 LEU A CG  1 
ATOM   969  C CD1 . LEU A 1 137 ? -22.530 -28.050 -28.407 1.00 32.51 ? 137 LEU A CD1 1 
ATOM   970  C CD2 . LEU A 1 137 ? -24.126 -27.010 -30.039 1.00 30.92 ? 137 LEU A CD2 1 
ATOM   971  N N   . LYS A 1 138 ? -22.845 -31.482 -28.609 1.00 35.54 ? 138 LYS A N   1 
ATOM   972  C CA  . LYS A 1 138 ? -23.808 -32.111 -27.673 1.00 35.95 ? 138 LYS A CA  1 
ATOM   973  C C   . LYS A 1 138 ? -24.054 -31.071 -26.587 1.00 33.58 ? 138 LYS A C   1 
ATOM   974  O O   . LYS A 1 138 ? -23.136 -30.754 -25.828 1.00 34.15 ? 138 LYS A O   1 
ATOM   975  C CB  . LYS A 1 138 ? -23.262 -33.467 -27.207 1.00 40.44 ? 138 LYS A CB  1 
ATOM   976  C CG  . LYS A 1 138 ? -23.883 -33.997 -25.927 1.00 50.03 ? 138 LYS A CG  1 
ATOM   977  C CD  . LYS A 1 138 ? -23.672 -35.492 -25.689 1.00 54.24 ? 138 LYS A CD  1 
ATOM   978  C CE  . LYS A 1 138 ? -23.903 -35.891 -24.241 1.00 64.54 ? 138 LYS A CE  1 
ATOM   979  N NZ  . LYS A 1 138 ? -24.833 -37.042 -24.107 1.00 68.22 ? 138 LYS A NZ  1 
ATOM   980  N N   . GLU A 1 139 ? -25.253 -30.501 -26.564 1.00 39.23 ? 139 GLU A N   1 
ATOM   981  C CA  . GLU A 1 139 ? -25.559 -29.291 -25.762 1.00 37.43 ? 139 GLU A CA  1 
ATOM   982  C C   . GLU A 1 139 ? -25.263 -29.537 -24.287 1.00 34.50 ? 139 GLU A C   1 
ATOM   983  O O   . GLU A 1 139 ? -24.933 -28.567 -23.599 1.00 36.27 ? 139 GLU A O   1 
ATOM   984  C CB  . GLU A 1 139 ? -27.005 -28.866 -25.957 1.00 36.13 ? 139 GLU A CB  1 
ATOM   985  C CG  . GLU A 1 139 ? -27.213 -28.141 -27.265 1.00 41.03 ? 139 GLU A CG  1 
ATOM   986  C CD  . GLU A 1 139 ? -28.483 -27.308 -27.278 1.00 50.03 ? 139 GLU A CD  1 
ATOM   987  O OE1 . GLU A 1 139 ? -29.511 -27.823 -26.759 1.00 41.68 ? 139 GLU A OE1 1 
ATOM   988  O OE2 . GLU A 1 139 ? -28.418 -26.127 -27.758 1.00 50.39 ? 139 GLU A OE2 1 
ATOM   989  N N   . THR A 1 140 ? -25.382 -30.775 -23.832 1.00 36.29 ? 140 THR A N   1 
ATOM   990  C CA  . THR A 1 140 ? -25.365 -31.159 -22.399 1.00 41.00 ? 140 THR A CA  1 
ATOM   991  C C   . THR A 1 140 ? -23.939 -31.517 -21.940 1.00 44.09 ? 140 THR A C   1 
ATOM   992  O O   . THR A 1 140 ? -23.729 -31.643 -20.718 1.00 44.79 ? 140 THR A O   1 
ATOM   993  C CB  . THR A 1 140 ? -26.340 -32.326 -22.184 1.00 47.50 ? 140 THR A CB  1 
ATOM   994  O OG1 . THR A 1 140 ? -25.830 -33.427 -22.942 1.00 49.75 ? 140 THR A OG1 1 
ATOM   995  C CG2 . THR A 1 140 ? -27.767 -31.993 -22.585 1.00 43.02 ? 140 THR A CG2 1 
ATOM   996  N N   . ASP A 1 141 ? -22.994 -31.673 -22.874 1.00 39.14 ? 141 ASP A N   1 
ATOM   997  C CA  . ASP A 1 141 ? -21.641 -32.216 -22.593 1.00 36.49 ? 141 ASP A CA  1 
ATOM   998  C C   . ASP A 1 141 ? -20.748 -31.120 -22.013 1.00 36.73 ? 141 ASP A C   1 
ATOM   999  O O   . ASP A 1 141 ? -20.348 -30.185 -22.716 1.00 35.96 ? 141 ASP A O   1 
ATOM   1000 C CB  . ASP A 1 141 ? -21.038 -32.791 -23.866 1.00 35.72 ? 141 ASP A CB  1 
ATOM   1001 C CG  . ASP A 1 141 ? -19.684 -33.408 -23.663 1.00 33.47 ? 141 ASP A CG  1 
ATOM   1002 O OD1 . ASP A 1 141 ? -19.118 -33.211 -22.576 1.00 33.40 ? 141 ASP A OD1 1 
ATOM   1003 O OD2 . ASP A 1 141 ? -19.232 -34.100 -24.593 1.00 33.89 ? 141 ASP A OD2 1 
ATOM   1004 N N   . PRO A 1 142 ? -20.354 -31.234 -20.726 1.00 35.84 ? 142 PRO A N   1 
ATOM   1005 C CA  . PRO A 1 142 ? -19.572 -30.188 -20.058 1.00 36.11 ? 142 PRO A CA  1 
ATOM   1006 C C   . PRO A 1 142 ? -18.160 -30.029 -20.646 1.00 36.03 ? 142 PRO A C   1 
ATOM   1007 O O   . PRO A 1 142 ? -17.577 -28.995 -20.453 1.00 36.09 ? 142 PRO A O   1 
ATOM   1008 C CB  . PRO A 1 142 ? -19.469 -30.719 -18.623 1.00 37.62 ? 142 PRO A CB  1 
ATOM   1009 C CG  . PRO A 1 142 ? -19.515 -32.224 -18.806 1.00 37.14 ? 142 PRO A CG  1 
ATOM   1010 C CD  . PRO A 1 142 ? -20.563 -32.417 -19.875 1.00 37.46 ? 142 PRO A CD  1 
ATOM   1011 N N   . ASN A 1 143 ? -17.678 -31.059 -21.353 1.00 32.23 ? 143 ASN A N   1 
ATOM   1012 C CA  . ASN A 1 143 ? -16.365 -31.103 -22.042 1.00 34.56 ? 143 ASN A CA  1 
ATOM   1013 C C   . ASN A 1 143 ? -16.333 -30.209 -23.279 1.00 32.91 ? 143 ASN A C   1 
ATOM   1014 O O   . ASN A 1 143 ? -15.226 -30.068 -23.863 1.00 32.10 ? 143 ASN A O   1 
ATOM   1015 C CB  . ASN A 1 143 ? -15.998 -32.518 -22.468 1.00 35.77 ? 143 ASN A CB  1 
ATOM   1016 C CG  . ASN A 1 143 ? -15.825 -33.412 -21.269 1.00 36.33 ? 143 ASN A CG  1 
ATOM   1017 O OD1 . ASN A 1 143 ? -16.060 -32.983 -20.147 1.00 40.28 ? 143 ASN A OD1 1 
ATOM   1018 N ND2 . ASN A 1 143 ? -15.430 -34.645 -21.498 1.00 38.67 ? 143 ASN A ND2 1 
ATOM   1019 N N   . GLN A 1 144 ? -17.468 -29.633 -23.667 1.00 28.96 ? 144 GLN A N   1 
ATOM   1020 C CA  . GLN A 1 144 ? -17.507 -28.675 -24.796 1.00 29.93 ? 144 GLN A CA  1 
ATOM   1021 C C   . GLN A 1 144 ? -17.943 -27.309 -24.298 1.00 28.95 ? 144 GLN A C   1 
ATOM   1022 O O   . GLN A 1 144 ? -18.056 -26.435 -25.125 1.00 30.72 ? 144 GLN A O   1 
ATOM   1023 C CB  . GLN A 1 144 ? -18.430 -29.154 -25.911 1.00 29.96 ? 144 GLN A CB  1 
ATOM   1024 C CG  . GLN A 1 144 ? -17.920 -30.388 -26.609 1.00 28.55 ? 144 GLN A CG  1 
ATOM   1025 C CD  . GLN A 1 144 ? -18.994 -30.945 -27.503 1.00 32.99 ? 144 GLN A CD  1 
ATOM   1026 O OE1 . GLN A 1 144 ? -20.183 -30.721 -27.257 1.00 30.93 ? 144 GLN A OE1 1 
ATOM   1027 N NE2 . GLN A 1 144 ? -18.574 -31.628 -28.567 1.00 32.80 ? 144 GLN A NE2 1 
ATOM   1028 N N   . ARG A 1 145 ? -18.127 -27.135 -22.996 1.00 33.67 ? 145 ARG A N   1 
ATOM   1029 C CA  . ARG A 1 145 ? -18.518 -25.833 -22.391 1.00 37.54 ? 145 ARG A CA  1 
ATOM   1030 C C   . ARG A 1 145 ? -17.258 -25.032 -22.078 1.00 34.47 ? 145 ARG A C   1 
ATOM   1031 O O   . ARG A 1 145 ? -16.489 -25.507 -21.224 1.00 30.88 ? 145 ARG A O   1 
ATOM   1032 C CB  . ARG A 1 145 ? -19.295 -26.031 -21.081 1.00 42.90 ? 145 ARG A CB  1 
ATOM   1033 C CG  . ARG A 1 145 ? -20.639 -26.729 -21.234 1.00 48.13 ? 145 ARG A CG  1 
ATOM   1034 C CD  . ARG A 1 145 ? -21.469 -26.131 -22.342 1.00 49.95 ? 145 ARG A CD  1 
ATOM   1035 N NE  . ARG A 1 145 ? -22.803 -26.706 -22.417 1.00 55.72 ? 145 ARG A NE  1 
ATOM   1036 C CZ  . ARG A 1 145 ? -23.858 -26.315 -21.710 1.00 55.62 ? 145 ARG A CZ  1 
ATOM   1037 N NH1 . ARG A 1 145 ? -23.773 -25.350 -20.809 1.00 56.83 ? 145 ARG A NH1 1 
ATOM   1038 N NH2 . ARG A 1 145 ? -25.015 -26.906 -21.915 1.00 58.20 ? 145 ARG A NH2 1 
ATOM   1039 N N   . ILE A 1 146 ? -17.120 -23.836 -22.668 1.00 32.43 ? 146 ILE A N   1 
ATOM   1040 C CA  . ILE A 1 146 ? -15.976 -22.905 -22.435 1.00 32.79 ? 146 ILE A CA  1 
ATOM   1041 C C   . ILE A 1 146 ? -16.439 -21.671 -21.640 1.00 33.07 ? 146 ILE A C   1 
ATOM   1042 O O   . ILE A 1 146 ? -17.540 -21.177 -21.878 1.00 31.07 ? 146 ILE A O   1 
ATOM   1043 C CB  . ILE A 1 146 ? -15.330 -22.523 -23.786 1.00 34.92 ? 146 ILE A CB  1 
ATOM   1044 C CG1 . ILE A 1 146 ? -15.017 -23.760 -24.642 1.00 34.16 ? 146 ILE A CG1 1 
ATOM   1045 C CG2 . ILE A 1 146 ? -14.101 -21.633 -23.591 1.00 34.55 ? 146 ILE A CG2 1 
ATOM   1046 C CD1 . ILE A 1 146 ? -14.114 -24.773 -23.982 1.00 34.60 ? 146 ILE A CD1 1 
ATOM   1047 N N   . LYS A 1 147 ? -15.602 -21.208 -20.710 1.00 38.06 ? 147 LYS A N   1 
ATOM   1048 C CA  . LYS A 1 147 ? -15.723 -19.917 -19.978 1.00 39.76 ? 147 LYS A CA  1 
ATOM   1049 C C   . LYS A 1 147 ? -14.444 -19.114 -20.224 1.00 34.26 ? 147 LYS A C   1 
ATOM   1050 O O   . LYS A 1 147 ? -13.374 -19.724 -20.388 1.00 30.49 ? 147 LYS A O   1 
ATOM   1051 C CB  . LYS A 1 147 ? -15.828 -20.113 -18.464 1.00 45.94 ? 147 LYS A CB  1 
ATOM   1052 C CG  . LYS A 1 147 ? -17.209 -20.367 -17.878 1.00 54.59 ? 147 LYS A CG  1 
ATOM   1053 C CD  . LYS A 1 147 ? -17.220 -21.459 -16.780 1.00 59.31 ? 147 LYS A CD  1 
ATOM   1054 C CE  . LYS A 1 147 ? -15.942 -21.549 -15.957 1.00 62.60 ? 147 LYS A CE  1 
ATOM   1055 N NZ  . LYS A 1 147 ? -15.666 -22.913 -15.421 1.00 58.79 ? 147 LYS A NZ  1 
ATOM   1056 N N   . PHE A 1 148 ? -14.575 -17.798 -20.203 1.00 29.37 ? 148 PHE A N   1 
ATOM   1057 C CA  . PHE A 1 148 ? -13.490 -16.819 -20.361 1.00 30.21 ? 148 PHE A CA  1 
ATOM   1058 C C   . PHE A 1 148 ? -13.364 -16.074 -19.050 1.00 32.83 ? 148 PHE A C   1 
ATOM   1059 O O   . PHE A 1 148 ? -14.363 -15.493 -18.649 1.00 36.83 ? 148 PHE A O   1 
ATOM   1060 C CB  . PHE A 1 148 ? -13.837 -15.847 -21.478 1.00 30.35 ? 148 PHE A CB  1 
ATOM   1061 C CG  . PHE A 1 148 ? -14.034 -16.542 -22.792 1.00 31.63 ? 148 PHE A CG  1 
ATOM   1062 C CD1 . PHE A 1 148 ? -12.946 -17.035 -23.492 1.00 31.00 ? 148 PHE A CD1 1 
ATOM   1063 C CD2 . PHE A 1 148 ? -15.299 -16.754 -23.299 1.00 33.21 ? 148 PHE A CD2 1 
ATOM   1064 C CE1 . PHE A 1 148 ? -13.120 -17.733 -24.674 1.00 32.46 ? 148 PHE A CE1 1 
ATOM   1065 C CE2 . PHE A 1 148 ? -15.474 -17.441 -24.494 1.00 35.30 ? 148 PHE A CE2 1 
ATOM   1066 C CZ  . PHE A 1 148 ? -14.385 -17.920 -25.185 1.00 35.59 ? 148 PHE A CZ  1 
ATOM   1067 N N   . ALA A 1 149 ? -12.213 -16.120 -18.388 1.00 34.63 ? 149 ALA A N   1 
ATOM   1068 C CA  . ALA A 1 149 ? -11.985 -15.350 -17.145 1.00 38.20 ? 149 ALA A CA  1 
ATOM   1069 C C   . ALA A 1 149 ? -10.934 -14.297 -17.451 1.00 37.92 ? 149 ALA A C   1 
ATOM   1070 O O   . ALA A 1 149 ? -9.879  -14.713 -17.938 1.00 41.44 ? 149 ALA A O   1 
ATOM   1071 C CB  . ALA A 1 149 ? -11.552 -16.243 -16.010 1.00 36.09 ? 149 ALA A CB  1 
ATOM   1072 N N   . VAL A 1 150 ? -11.221 -13.024 -17.168 1.00 40.56 ? 150 VAL A N   1 
ATOM   1073 C CA  . VAL A 1 150 ? -10.267 -11.895 -17.397 1.00 49.12 ? 150 VAL A CA  1 
ATOM   1074 C C   . VAL A 1 150 ? -9.463  -11.676 -16.115 1.00 50.80 ? 150 VAL A C   1 
ATOM   1075 O O   . VAL A 1 150 ? -10.096 -11.570 -15.066 1.00 46.86 ? 150 VAL A O   1 
ATOM   1076 C CB  . VAL A 1 150 ? -10.981 -10.612 -17.853 1.00 52.43 ? 150 VAL A CB  1 
ATOM   1077 C CG1 . VAL A 1 150 ? -9.975  -9.523  -18.201 1.00 55.69 ? 150 VAL A CG1 1 
ATOM   1078 C CG2 . VAL A 1 150 ? -11.914 -10.886 -19.023 1.00 48.92 ? 150 VAL A CG2 1 
ATOM   1079 N N   . ASP A 1 151 ? -8.123  -11.666 -16.215 1.00 61.78 ? 151 ASP A N   1 
ATOM   1080 C CA  . ASP A 1 151 ? -7.169  -11.509 -15.077 1.00 67.22 ? 151 ASP A CA  1 
ATOM   1081 C C   . ASP A 1 151 ? -7.275  -12.715 -14.137 1.00 64.99 ? 151 ASP A C   1 
ATOM   1082 O O   . ASP A 1 151 ? -6.255  -12.978 -13.499 1.00 68.19 ? 151 ASP A O   1 
ATOM   1083 C CB  . ASP A 1 151 ? -7.379  -10.191 -14.314 1.00 71.11 ? 151 ASP A CB  1 
ATOM   1084 C CG  . ASP A 1 151 ? -6.248  -9.194  -14.498 1.00 73.37 ? 151 ASP A CG  1 
ATOM   1085 O OD1 . ASP A 1 151 ? -5.609  -9.213  -15.581 1.00 73.71 ? 151 ASP A OD1 1 
ATOM   1086 O OD2 . ASP A 1 151 ? -6.001  -8.421  -13.554 1.00 76.85 ? 151 ASP A OD2 1 
ATOM   1087 N N   . LYS B 1 6   ? 7.019   -9.671  -9.774  1.00 58.96 ? 6   LYS B N   1 
ATOM   1088 C CA  . LYS B 1 6   ? 8.299   -8.906  -9.648  1.00 63.08 ? 6   LYS B CA  1 
ATOM   1089 C C   . LYS B 1 6   ? 9.238   -9.671  -8.713  1.00 54.54 ? 6   LYS B C   1 
ATOM   1090 O O   . LYS B 1 6   ? 8.793   -10.101 -7.640  1.00 49.66 ? 6   LYS B O   1 
ATOM   1091 C CB  . LYS B 1 6   ? 8.088   -7.486  -9.108  1.00 68.62 ? 6   LYS B CB  1 
ATOM   1092 C CG  . LYS B 1 6   ? 7.308   -6.537  -10.013 1.00 77.33 ? 6   LYS B CG  1 
ATOM   1093 C CD  . LYS B 1 6   ? 5.844   -6.329  -9.610  1.00 81.01 ? 6   LYS B CD  1 
ATOM   1094 C CE  . LYS B 1 6   ? 5.013   -5.615  -10.665 1.00 78.39 ? 6   LYS B CE  1 
ATOM   1095 N NZ  . LYS B 1 6   ? 5.443   -4.208  -10.857 1.00 76.49 ? 6   LYS B NZ  1 
ATOM   1096 N N   . ILE B 1 7   ? 10.491  -9.844  -9.130  1.00 49.94 ? 7   ILE B N   1 
ATOM   1097 C CA  . ILE B 1 7   ? 11.593  -10.378 -8.279  1.00 48.48 ? 7   ILE B CA  1 
ATOM   1098 C C   . ILE B 1 7   ? 11.824  -9.339  -7.183  1.00 45.78 ? 7   ILE B C   1 
ATOM   1099 O O   . ILE B 1 7   ? 11.919  -8.155  -7.479  1.00 44.56 ? 7   ILE B O   1 
ATOM   1100 C CB  . ILE B 1 7   ? 12.867  -10.637 -9.121  1.00 46.24 ? 7   ILE B CB  1 
ATOM   1101 C CG1 . ILE B 1 7   ? 12.610  -11.587 -10.300 1.00 47.69 ? 7   ILE B CG1 1 
ATOM   1102 C CG2 . ILE B 1 7   ? 13.991  -11.150 -8.241  1.00 45.67 ? 7   ILE B CG2 1 
ATOM   1103 C CD1 . ILE B 1 7   ? 13.337  -11.214 -11.582 1.00 47.89 ? 7   ILE B CD1 1 
ATOM   1104 N N   . PRO B 1 8   ? 11.909  -9.719  -5.889  1.00 43.63 ? 8   PRO B N   1 
ATOM   1105 C CA  . PRO B 1 8   ? 12.281  -8.762  -4.849  1.00 38.84 ? 8   PRO B CA  1 
ATOM   1106 C C   . PRO B 1 8   ? 13.800  -8.469  -4.884  1.00 42.56 ? 8   PRO B C   1 
ATOM   1107 O O   . PRO B 1 8   ? 14.581  -9.119  -4.231  1.00 40.64 ? 8   PRO B O   1 
ATOM   1108 C CB  . PRO B 1 8   ? 11.744  -9.437  -3.589  1.00 40.16 ? 8   PRO B CB  1 
ATOM   1109 C CG  . PRO B 1 8   ? 11.826  -10.917 -3.878  1.00 41.92 ? 8   PRO B CG  1 
ATOM   1110 C CD  . PRO B 1 8   ? 11.689  -11.080 -5.374  1.00 44.37 ? 8   PRO B CD  1 
ATOM   1111 N N   . LEU B 1 9   ? 14.189  -7.469  -5.680  1.00 41.87 ? 9   LEU B N   1 
ATOM   1112 C CA  . LEU B 1 9   ? 15.589  -7.012  -5.868  1.00 41.32 ? 9   LEU B CA  1 
ATOM   1113 C C   . LEU B 1 9   ? 15.972  -6.051  -4.750  1.00 38.76 ? 9   LEU B C   1 
ATOM   1114 O O   . LEU B 1 9   ? 15.170  -5.202  -4.413  1.00 35.38 ? 9   LEU B O   1 
ATOM   1115 C CB  . LEU B 1 9   ? 15.719  -6.278  -7.204  1.00 45.08 ? 9   LEU B CB  1 
ATOM   1116 C CG  . LEU B 1 9   ? 15.971  -7.145  -8.426  1.00 46.48 ? 9   LEU B CG  1 
ATOM   1117 C CD1 . LEU B 1 9   ? 15.771  -6.317  -9.682  1.00 44.70 ? 9   LEU B CD1 1 
ATOM   1118 C CD2 . LEU B 1 9   ? 17.375  -7.745  -8.363  1.00 51.68 ? 9   LEU B CD2 1 
ATOM   1119 N N   . ASP B 1 10  ? 17.202  -6.157  -4.252  1.00 38.02 ? 10  ASP B N   1 
ATOM   1120 C CA  . ASP B 1 10  ? 17.764  -5.144  -3.342  1.00 32.22 ? 10  ASP B CA  1 
ATOM   1121 C C   . ASP B 1 10  ? 16.923  -5.124  -2.070  1.00 30.58 ? 10  ASP B C   1 
ATOM   1122 O O   . ASP B 1 10  ? 16.835  -4.081  -1.448  1.00 28.80 ? 10  ASP B O   1 
ATOM   1123 C CB  . ASP B 1 10  ? 17.748  -3.788  -4.042  1.00 32.92 ? 10  ASP B CB  1 
ATOM   1124 C CG  . ASP B 1 10  ? 18.385  -3.786  -5.424  1.00 30.89 ? 10  ASP B CG  1 
ATOM   1125 O OD1 . ASP B 1 10  ? 19.101  -4.745  -5.765  1.00 31.49 ? 10  ASP B OD1 1 
ATOM   1126 O OD2 . ASP B 1 10  ? 18.219  -2.800  -6.104  1.00 28.64 ? 10  ASP B OD2 1 
ATOM   1127 N N   . LEU B 1 11  ? 16.326  -6.246  -1.706  1.00 30.18 ? 11  LEU B N   1 
ATOM   1128 C CA  . LEU B 1 11  ? 15.567  -6.378  -0.447  1.00 34.01 ? 11  LEU B CA  1 
ATOM   1129 C C   . LEU B 1 11  ? 16.268  -7.398  0.452   1.00 36.09 ? 11  LEU B C   1 
ATOM   1130 O O   . LEU B 1 11  ? 16.068  -8.599  0.333   1.00 32.69 ? 11  LEU B O   1 
ATOM   1131 C CB  . LEU B 1 11  ? 14.126  -6.768  -0.789  1.00 36.40 ? 11  LEU B CB  1 
ATOM   1132 C CG  . LEU B 1 11  ? 13.295  -5.660  -1.434  1.00 38.52 ? 11  LEU B CG  1 
ATOM   1133 C CD1 . LEU B 1 11  ? 11.867  -6.137  -1.651  1.00 39.90 ? 11  LEU B CD1 1 
ATOM   1134 C CD2 . LEU B 1 11  ? 13.319  -4.397  -0.588  1.00 37.15 ? 11  LEU B CD2 1 
ATOM   1135 N N   . PRO B 1 12  ? 17.115  -6.931  1.390   1.00 38.65 ? 12  PRO B N   1 
ATOM   1136 C CA  . PRO B 1 12  ? 17.908  -7.820  2.241   1.00 39.36 ? 12  PRO B CA  1 
ATOM   1137 C C   . PRO B 1 12  ? 17.134  -8.849  3.087   1.00 41.26 ? 12  PRO B C   1 
ATOM   1138 O O   . PRO B 1 12  ? 17.656  -9.909  3.456   1.00 43.46 ? 12  PRO B O   1 
ATOM   1139 C CB  . PRO B 1 12  ? 18.563  -6.800  3.184   1.00 40.52 ? 12  PRO B CB  1 
ATOM   1140 C CG  . PRO B 1 12  ? 18.676  -5.540  2.361   1.00 37.47 ? 12  PRO B CG  1 
ATOM   1141 C CD  . PRO B 1 12  ? 17.369  -5.501  1.636   1.00 37.17 ? 12  PRO B CD  1 
ATOM   1142 N N   . GLY B 1 13  ? 15.898  -8.540  3.435   1.00 42.42 ? 13  GLY B N   1 
ATOM   1143 C CA  . GLY B 1 13  ? 15.147  -9.441  4.326   1.00 48.08 ? 13  GLY B CA  1 
ATOM   1144 C C   . GLY B 1 13  ? 14.615  -10.676 3.619   1.00 45.07 ? 13  GLY B C   1 
ATOM   1145 O O   . GLY B 1 13  ? 13.743  -11.305 4.186   1.00 54.85 ? 13  GLY B O   1 
ATOM   1146 N N   . THR B 1 14  ? 15.042  -11.004 2.403   1.00 45.62 ? 14  THR B N   1 
ATOM   1147 C CA  . THR B 1 14  ? 14.272  -11.946 1.547   1.00 43.18 ? 14  THR B CA  1 
ATOM   1148 C C   . THR B 1 14  ? 14.578  -13.377 1.997   1.00 38.69 ? 14  THR B C   1 
ATOM   1149 O O   . THR B 1 14  ? 15.762  -13.666 2.238   1.00 35.32 ? 14  THR B O   1 
ATOM   1150 C CB  . THR B 1 14  ? 14.522  -11.707 0.049   1.00 47.44 ? 14  THR B CB  1 
ATOM   1151 O OG1 . THR B 1 14  ? 14.117  -10.378 -0.296  1.00 45.64 ? 14  THR B OG1 1 
ATOM   1152 C CG2 . THR B 1 14  ? 13.747  -12.666 -0.832  1.00 44.97 ? 14  THR B CG2 1 
ATOM   1153 N N   . ARG B 1 15  ? 13.546  -14.219 2.104   1.00 35.12 ? 15  ARG B N   1 
ATOM   1154 C CA  . ARG B 1 15  ? 13.663  -15.697 2.298   1.00 38.34 ? 15  ARG B CA  1 
ATOM   1155 C C   . ARG B 1 15  ? 13.372  -16.402 0.968   1.00 34.27 ? 15  ARG B C   1 
ATOM   1156 O O   . ARG B 1 15  ? 12.573  -15.888 0.183   1.00 35.23 ? 15  ARG B O   1 
ATOM   1157 C CB  . ARG B 1 15  ? 12.692  -16.220 3.368   1.00 40.07 ? 15  ARG B CB  1 
ATOM   1158 C CG  . ARG B 1 15  ? 12.969  -15.696 4.770   1.00 43.75 ? 15  ARG B CG  1 
ATOM   1159 C CD  . ARG B 1 15  ? 12.058  -16.203 5.872   1.00 45.70 ? 15  ARG B CD  1 
ATOM   1160 N NE  . ARG B 1 15  ? 12.836  -16.408 7.096   1.00 60.75 ? 15  ARG B NE  1 
ATOM   1161 C CZ  . ARG B 1 15  ? 12.339  -16.742 8.302   1.00 70.17 ? 15  ARG B CZ  1 
ATOM   1162 N NH1 . ARG B 1 15  ? 11.036  -16.908 8.468   1.00 65.23 ? 15  ARG B NH1 1 
ATOM   1163 N NH2 . ARG B 1 15  ? 13.151  -16.921 9.342   1.00 66.25 ? 15  ARG B NH2 1 
ATOM   1164 N N   . ILE B 1 16  ? 14.001  -17.542 0.719   1.00 33.05 ? 16  ILE B N   1 
ATOM   1165 C CA  . ILE B 1 16  ? 13.789  -18.339 -0.526  1.00 32.26 ? 16  ILE B CA  1 
ATOM   1166 C C   . ILE B 1 16  ? 13.063  -19.609 -0.096  1.00 32.02 ? 16  ILE B C   1 
ATOM   1167 O O   . ILE B 1 16  ? 13.600  -20.345 0.740   1.00 36.21 ? 16  ILE B O   1 
ATOM   1168 C CB  . ILE B 1 16  ? 15.114  -18.570 -1.282  1.00 29.87 ? 16  ILE B CB  1 
ATOM   1169 C CG1 . ILE B 1 16  ? 15.716  -17.231 -1.720  1.00 33.26 ? 16  ILE B CG1 1 
ATOM   1170 C CG2 . ILE B 1 16  ? 14.944  -19.509 -2.452  1.00 30.41 ? 16  ILE B CG2 1 
ATOM   1171 C CD1 . ILE B 1 16  ? 17.204  -17.276 -1.986  1.00 32.96 ? 16  ILE B CD1 1 
ATOM   1172 N N   . LEU B 1 17  ? 11.858  -19.809 -0.629  1.00 33.97 ? 17  LEU B N   1 
ATOM   1173 C CA  . LEU B 1 17  ? 10.893  -20.835 -0.166  1.00 34.81 ? 17  LEU B CA  1 
ATOM   1174 C C   . LEU B 1 17  ? 10.674  -21.902 -1.256  1.00 35.90 ? 17  LEU B C   1 
ATOM   1175 O O   . LEU B 1 17  ? 10.565  -21.578 -2.471  1.00 33.18 ? 17  LEU B O   1 
ATOM   1176 C CB  . LEU B 1 17  ? 9.580   -20.132 0.184   1.00 36.47 ? 17  LEU B CB  1 
ATOM   1177 C CG  . LEU B 1 17  ? 9.478   -19.477 1.557   1.00 40.03 ? 17  LEU B CG  1 
ATOM   1178 C CD1 . LEU B 1 17  ? 10.504  -18.363 1.758   1.00 42.44 ? 17  LEU B CD1 1 
ATOM   1179 C CD2 . LEU B 1 17  ? 8.077   -18.913 1.722   1.00 44.17 ? 17  LEU B CD2 1 
ATOM   1180 N N   . ASN B 1 18  ? 10.605  -23.156 -0.833  1.00 35.48 ? 18  ASN B N   1 
ATOM   1181 C CA  . ASN B 1 18  ? 10.054  -24.260 -1.652  1.00 36.77 ? 18  ASN B CA  1 
ATOM   1182 C C   . ASN B 1 18  ? 9.055   -25.026 -0.774  1.00 37.22 ? 18  ASN B C   1 
ATOM   1183 O O   . ASN B 1 18  ? 9.514   -25.685 0.227   1.00 32.64 ? 18  ASN B O   1 
ATOM   1184 C CB  . ASN B 1 18  ? 11.160  -25.150 -2.204  1.00 35.38 ? 18  ASN B CB  1 
ATOM   1185 C CG  . ASN B 1 18  ? 10.577  -26.251 -3.057  1.00 35.94 ? 18  ASN B CG  1 
ATOM   1186 O OD1 . ASN B 1 18  ? 10.601  -27.405 -2.651  1.00 34.58 ? 18  ASN B OD1 1 
ATOM   1187 N ND2 . ASN B 1 18  ? 10.016  -25.886 -4.206  1.00 33.38 ? 18  ASN B ND2 1 
ATOM   1188 N N   . GLY B 1 19  ? 7.765   -24.900 -1.103  1.00 34.76 ? 19  GLY B N   1 
ATOM   1189 C CA  . GLY B 1 19  ? 6.646   -25.275 -0.214  1.00 38.74 ? 19  GLY B CA  1 
ATOM   1190 C C   . GLY B 1 19  ? 6.757   -24.517 1.099   1.00 39.91 ? 19  GLY B C   1 
ATOM   1191 O O   . GLY B 1 19  ? 6.951   -23.290 1.052   1.00 46.82 ? 19  GLY B O   1 
ATOM   1192 N N   . ALA B 1 20  ? 6.724   -25.213 2.237   1.00 43.32 ? 20  ALA B N   1 
ATOM   1193 C CA  . ALA B 1 20  ? 6.906   -24.616 3.585   1.00 41.90 ? 20  ALA B CA  1 
ATOM   1194 C C   . ALA B 1 20  ? 8.405   -24.512 3.914   1.00 40.21 ? 20  ALA B C   1 
ATOM   1195 O O   . ALA B 1 20  ? 8.740   -23.864 4.930   1.00 40.73 ? 20  ALA B O   1 
ATOM   1196 C CB  . ALA B 1 20  ? 6.166   -25.413 4.631   1.00 40.24 ? 20  ALA B CB  1 
ATOM   1197 N N   . ASN B 1 21  ? 9.279   -25.102 3.092   1.00 35.82 ? 21  ASN B N   1 
ATOM   1198 C CA  . ASN B 1 21  ? 10.736  -25.099 3.361   1.00 35.96 ? 21  ASN B CA  1 
ATOM   1199 C C   . ASN B 1 21  ? 11.296  -23.759 2.916   1.00 34.03 ? 21  ASN B C   1 
ATOM   1200 O O   . ASN B 1 21  ? 10.638  -23.126 2.091   1.00 36.15 ? 21  ASN B O   1 
ATOM   1201 C CB  . ASN B 1 21  ? 11.421  -26.276 2.691   1.00 39.27 ? 21  ASN B CB  1 
ATOM   1202 C CG  . ASN B 1 21  ? 11.096  -27.569 3.401   1.00 41.99 ? 21  ASN B CG  1 
ATOM   1203 O OD1 . ASN B 1 21  ? 11.098  -27.626 4.629   1.00 44.46 ? 21  ASN B OD1 1 
ATOM   1204 N ND2 . ASN B 1 21  ? 10.830  -28.607 2.633   1.00 44.63 ? 21  ASN B ND2 1 
ATOM   1205 N N   . TRP B 1 22  ? 12.457  -23.365 3.437   1.00 33.34 ? 22  TRP B N   1 
ATOM   1206 C CA  . TRP B 1 22  ? 13.161  -22.118 3.025   1.00 35.49 ? 22  TRP B CA  1 
ATOM   1207 C C   . TRP B 1 22  ? 14.666  -22.313 3.158   1.00 34.04 ? 22  TRP B C   1 
ATOM   1208 O O   . TRP B 1 22  ? 15.105  -23.098 4.039   1.00 33.01 ? 22  TRP B O   1 
ATOM   1209 C CB  . TRP B 1 22  ? 12.653  -20.869 3.763   1.00 36.37 ? 22  TRP B CB  1 
ATOM   1210 C CG  . TRP B 1 22  ? 12.903  -20.785 5.239   1.00 36.92 ? 22  TRP B CG  1 
ATOM   1211 C CD1 . TRP B 1 22  ? 14.001  -20.248 5.837   1.00 37.42 ? 22  TRP B CD1 1 
ATOM   1212 C CD2 . TRP B 1 22  ? 12.010  -21.159 6.310   1.00 37.48 ? 22  TRP B CD2 1 
ATOM   1213 N NE1 . TRP B 1 22  ? 13.867  -20.279 7.198   1.00 38.33 ? 22  TRP B NE1 1 
ATOM   1214 C CE2 . TRP B 1 22  ? 12.657  -20.832 7.523   1.00 41.05 ? 22  TRP B CE2 1 
ATOM   1215 C CE3 . TRP B 1 22  ? 10.732  -21.728 6.377   1.00 37.21 ? 22  TRP B CE3 1 
ATOM   1216 C CZ2 . TRP B 1 22  ? 12.072  -21.068 8.775   1.00 41.45 ? 22  TRP B CZ2 1 
ATOM   1217 C CZ3 . TRP B 1 22  ? 10.162  -21.980 7.608   1.00 37.05 ? 22  TRP B CZ3 1 
ATOM   1218 C CH2 . TRP B 1 22  ? 10.810  -21.627 8.792   1.00 38.39 ? 22  TRP B CH2 1 
ATOM   1219 N N   . ALA B 1 23  ? 15.399  -21.652 2.262   1.00 31.31 ? 23  ALA B N   1 
ATOM   1220 C CA  . ALA B 1 23  ? 16.852  -21.821 2.050   1.00 30.62 ? 23  ALA B CA  1 
ATOM   1221 C C   . ALA B 1 23  ? 17.638  -21.233 3.233   1.00 29.59 ? 23  ALA B C   1 
ATOM   1222 O O   . ALA B 1 23  ? 17.352  -20.094 3.630   1.00 29.57 ? 23  ALA B O   1 
ATOM   1223 C CB  . ALA B 1 23  ? 17.224  -21.178 0.739   1.00 31.11 ? 23  ALA B CB  1 
ATOM   1224 N N   . ASN B 1 24  ? 18.552  -22.017 3.806   1.00 32.23 ? 24  ASN B N   1 
ATOM   1225 C CA  . ASN B 1 24  ? 19.573  -21.600 4.808   1.00 34.23 ? 24  ASN B CA  1 
ATOM   1226 C C   . ASN B 1 24  ? 20.956  -21.874 4.217   1.00 34.33 ? 24  ASN B C   1 
ATOM   1227 O O   . ASN B 1 24  ? 21.083  -22.733 3.311   1.00 37.82 ? 24  ASN B O   1 
ATOM   1228 C CB  . ASN B 1 24  ? 19.543  -22.375 6.134   1.00 33.49 ? 24  ASN B CB  1 
ATOM   1229 C CG  . ASN B 1 24  ? 18.178  -22.510 6.777   1.00 39.54 ? 24  ASN B CG  1 
ATOM   1230 O OD1 . ASN B 1 24  ? 17.353  -21.592 6.750   1.00 36.59 ? 24  ASN B OD1 1 
ATOM   1231 N ND2 . ASN B 1 24  ? 17.945  -23.660 7.400   1.00 44.37 ? 24  ASN B ND2 1 
ATOM   1232 N N   . ASN B 1 25  ? 21.977  -21.226 4.757   1.00 35.53 ? 25  ASN B N   1 
ATOM   1233 C CA  . ASN B 1 25  ? 23.368  -21.441 4.298   1.00 33.55 ? 25  ASN B CA  1 
ATOM   1234 C C   . ASN B 1 25  ? 24.348  -20.848 5.316   1.00 33.47 ? 25  ASN B C   1 
ATOM   1235 O O   . ASN B 1 25  ? 24.131  -19.697 5.711   1.00 35.22 ? 25  ASN B O   1 
ATOM   1236 C CB  . ASN B 1 25  ? 23.572  -20.871 2.900   1.00 30.70 ? 25  ASN B CB  1 
ATOM   1237 C CG  . ASN B 1 25  ? 24.997  -21.069 2.437   1.00 31.87 ? 25  ASN B CG  1 
ATOM   1238 O OD1 . ASN B 1 25  ? 25.802  -20.136 2.504   1.00 31.19 ? 25  ASN B OD1 1 
ATOM   1239 N ND2 . ASN B 1 25  ? 25.315  -22.286 2.022   1.00 27.95 ? 25  ASN B ND2 1 
ATOM   1240 N N   . SER B 1 26  ? 25.397  -21.604 5.664   1.00 31.87 ? 26  SER B N   1 
ATOM   1241 C CA  . SER B 1 26  ? 26.389  -21.264 6.713   1.00 34.06 ? 26  SER B CA  1 
ATOM   1242 C C   . SER B 1 26  ? 27.661  -20.654 6.096   1.00 34.27 ? 26  SER B C   1 
ATOM   1243 O O   . SER B 1 26  ? 28.026  -21.026 4.954   1.00 30.14 ? 26  SER B O   1 
ATOM   1244 C CB  . SER B 1 26  ? 26.728  -22.487 7.520   1.00 36.39 ? 26  SER B CB  1 
ATOM   1245 O OG  . SER B 1 26  ? 25.634  -22.851 8.324   1.00 39.81 ? 26  SER B OG  1 
ATOM   1246 N N   . ALA B 1 27  ? 28.314  -19.766 6.849   1.00 35.12 ? 27  ALA B N   1 
ATOM   1247 C CA  . ALA B 1 27  ? 29.695  -19.299 6.601   1.00 39.07 ? 27  ALA B CA  1 
ATOM   1248 C C   . ALA B 1 27  ? 30.602  -20.526 6.557   1.00 37.98 ? 27  ALA B C   1 
ATOM   1249 O O   . ALA B 1 27  ? 30.389  -21.450 7.335   1.00 40.29 ? 27  ALA B O   1 
ATOM   1250 C CB  . ALA B 1 27  ? 30.153  -18.313 7.661   1.00 32.29 ? 27  ALA B CB  1 
ATOM   1251 N N   . THR B 1 28  ? 31.562  -20.518 5.649   1.00 45.33 ? 28  THR B N   1 
ATOM   1252 C CA  . THR B 1 28  ? 32.586  -21.574 5.474   1.00 50.62 ? 28  THR B CA  1 
ATOM   1253 C C   . THR B 1 28  ? 33.764  -21.254 6.390   1.00 58.15 ? 28  THR B C   1 
ATOM   1254 O O   . THR B 1 28  ? 33.556  -20.482 7.321   1.00 54.67 ? 28  THR B O   1 
ATOM   1255 C CB  . THR B 1 28  ? 33.013  -21.670 4.006   1.00 50.97 ? 28  THR B CB  1 
ATOM   1256 O OG1 . THR B 1 28  ? 34.030  -22.670 3.918   1.00 57.62 ? 28  THR B OG1 1 
ATOM   1257 C CG2 . THR B 1 28  ? 33.532  -20.367 3.453   1.00 48.47 ? 28  THR B CG2 1 
ATOM   1258 N N   . GLU B 1 29  ? 34.926  -21.876 6.148   1.00 75.89 ? 29  GLU B N   1 
ATOM   1259 C CA  . GLU B 1 29  ? 36.270  -21.416 6.610   1.00 76.95 ? 29  GLU B CA  1 
ATOM   1260 C C   . GLU B 1 29  ? 37.233  -21.480 5.415   1.00 75.02 ? 29  GLU B C   1 
ATOM   1261 O O   . GLU B 1 29  ? 38.024  -22.440 5.332   1.00 70.63 ? 29  GLU B O   1 
ATOM   1262 C CB  . GLU B 1 29  ? 36.732  -22.241 7.817   1.00 77.85 ? 29  GLU B CB  1 
ATOM   1263 C CG  . GLU B 1 29  ? 36.127  -21.768 9.127   1.00 76.75 ? 29  GLU B CG  1 
ATOM   1264 C CD  . GLU B 1 29  ? 36.309  -20.277 9.374   1.00 80.08 ? 29  GLU B CD  1 
ATOM   1265 O OE1 . GLU B 1 29  ? 35.383  -19.650 9.933   1.00 78.35 ? 29  GLU B OE1 1 
ATOM   1266 O OE2 . GLU B 1 29  ? 37.373  -19.735 8.988   1.00 78.35 ? 29  GLU B OE2 1 
ATOM   1267 N N   . ASN B 1 30  ? 37.152  -20.507 4.502   1.00 71.31 ? 30  ASN B N   1 
ATOM   1268 C CA  . ASN B 1 30  ? 37.791  -20.624 3.163   1.00 79.20 ? 30  ASN B CA  1 
ATOM   1269 C C   . ASN B 1 30  ? 39.269  -20.223 3.277   1.00 77.09 ? 30  ASN B C   1 
ATOM   1270 O O   . ASN B 1 30  ? 40.101  -21.153 3.281   1.00 73.39 ? 30  ASN B O   1 
ATOM   1271 C CB  . ASN B 1 30  ? 36.978  -19.883 2.092   1.00 79.82 ? 30  ASN B CB  1 
ATOM   1272 C CG  . ASN B 1 30  ? 37.413  -18.458 1.819   1.00 78.19 ? 30  ASN B CG  1 
ATOM   1273 O OD1 . ASN B 1 30  ? 37.395  -17.620 2.717   1.00 85.09 ? 30  ASN B OD1 1 
ATOM   1274 N ND2 . ASN B 1 30  ? 37.759  -18.168 0.572   1.00 73.71 ? 30  ASN B ND2 1 
ATOM   1275 N N   . ASN B 1 34  ? 39.007  -22.845 -3.093  1.00 66.73 ? 34  ASN B N   1 
ATOM   1276 C CA  . ASN B 1 34  ? 37.594  -22.945 -3.563  1.00 68.08 ? 34  ASN B CA  1 
ATOM   1277 C C   . ASN B 1 34  ? 36.776  -23.788 -2.553  1.00 60.51 ? 34  ASN B C   1 
ATOM   1278 O O   . ASN B 1 34  ? 36.694  -25.014 -2.708  1.00 56.05 ? 34  ASN B O   1 
ATOM   1279 C CB  . ASN B 1 34  ? 37.506  -23.482 -5.010  1.00 77.18 ? 34  ASN B CB  1 
ATOM   1280 C CG  . ASN B 1 34  ? 37.076  -22.490 -6.090  1.00 76.49 ? 34  ASN B CG  1 
ATOM   1281 O OD1 . ASN B 1 34  ? 37.388  -22.685 -7.266  1.00 68.03 ? 34  ASN B OD1 1 
ATOM   1282 N ND2 . ASN B 1 34  ? 36.312  -21.459 -5.748  1.00 70.14 ? 34  ASN B ND2 1 
ATOM   1283 N N   . SER B 1 35  ? 36.164  -23.141 -1.553  1.00 52.37 ? 35  SER B N   1 
ATOM   1284 C CA  . SER B 1 35  ? 35.327  -23.763 -0.489  1.00 45.57 ? 35  SER B CA  1 
ATOM   1285 C C   . SER B 1 35  ? 33.830  -23.497 -0.734  1.00 38.53 ? 35  SER B C   1 
ATOM   1286 O O   . SER B 1 35  ? 33.482  -22.782 -1.686  1.00 35.59 ? 35  SER B O   1 
ATOM   1287 C CB  . SER B 1 35  ? 35.736  -23.244 0.843   1.00 46.37 ? 35  SER B CB  1 
ATOM   1288 O OG  . SER B 1 35  ? 35.378  -21.876 0.960   1.00 54.05 ? 35  SER B OG  1 
ATOM   1289 N N   . GLY B 1 36  ? 32.962  -24.056 0.099   1.00 33.48 ? 36  GLY B N   1 
ATOM   1290 C CA  . GLY B 1 36  ? 31.507  -23.880 -0.041  1.00 29.98 ? 36  GLY B CA  1 
ATOM   1291 C C   . GLY B 1 36  ? 30.726  -24.697 0.965   1.00 28.69 ? 36  GLY B C   1 
ATOM   1292 O O   . GLY B 1 36  ? 31.266  -25.670 1.521   1.00 29.27 ? 36  GLY B O   1 
ATOM   1293 N N   . THR B 1 37  ? 29.473  -24.309 1.168   1.00 29.91 ? 37  THR B N   1 
ATOM   1294 C CA  . THR B 1 37  ? 28.526  -24.905 2.135   1.00 29.44 ? 37  THR B CA  1 
ATOM   1295 C C   . THR B 1 37  ? 27.188  -25.154 1.433   1.00 30.04 ? 37  THR B C   1 
ATOM   1296 O O   . THR B 1 37  ? 26.821  -24.389 0.529   1.00 27.48 ? 37  THR B O   1 
ATOM   1297 C CB  . THR B 1 37  ? 28.355  -23.998 3.355   1.00 30.36 ? 37  THR B CB  1 
ATOM   1298 O OG1 . THR B 1 37  ? 27.870  -22.717 2.935   1.00 29.85 ? 37  THR B OG1 1 
ATOM   1299 C CG2 . THR B 1 37  ? 29.655  -23.847 4.108   1.00 32.16 ? 37  THR B CG2 1 
ATOM   1300 N N   . LEU B 1 38  ? 26.477  -26.172 1.881   1.00 31.11 ? 38  LEU B N   1 
ATOM   1301 C CA  . LEU B 1 38  ? 25.208  -26.596 1.265   1.00 32.88 ? 38  LEU B CA  1 
ATOM   1302 C C   . LEU B 1 38  ? 24.195  -25.486 1.479   1.00 32.49 ? 38  LEU B C   1 
ATOM   1303 O O   . LEU B 1 38  ? 24.190  -24.864 2.560   1.00 29.93 ? 38  LEU B O   1 
ATOM   1304 C CB  . LEU B 1 38  ? 24.728  -27.915 1.882   1.00 33.87 ? 38  LEU B CB  1 
ATOM   1305 C CG  . LEU B 1 38  ? 25.547  -29.146 1.488   1.00 38.65 ? 38  LEU B CG  1 
ATOM   1306 C CD1 . LEU B 1 38  ? 25.133  -30.364 2.284   1.00 38.66 ? 38  LEU B CD1 1 
ATOM   1307 C CD2 . LEU B 1 38  ? 25.408  -29.437 0.007   1.00 40.94 ? 38  LEU B CD2 1 
ATOM   1308 N N   . ILE B 1 39  ? 23.394  -25.257 0.443   1.00 32.61 ? 39  ILE B N   1 
ATOM   1309 C CA  . ILE B 1 39  ? 22.099  -24.549 0.545   1.00 32.53 ? 39  ILE B CA  1 
ATOM   1310 C C   . ILE B 1 39  ? 21.101  -25.611 0.992   1.00 32.27 ? 39  ILE B C   1 
ATOM   1311 O O   . ILE B 1 39  ? 20.883  -26.627 0.255   1.00 31.94 ? 39  ILE B O   1 
ATOM   1312 C CB  . ILE B 1 39  ? 21.760  -23.804 -0.760  1.00 34.50 ? 39  ILE B CB  1 
ATOM   1313 C CG1 . ILE B 1 39  ? 22.842  -22.761 -1.070  1.00 36.59 ? 39  ILE B CG1 1 
ATOM   1314 C CG2 . ILE B 1 39  ? 20.375  -23.179 -0.678  1.00 35.30 ? 39  ILE B CG2 1 
ATOM   1315 C CD1 . ILE B 1 39  ? 22.613  -21.965 -2.336  1.00 39.46 ? 39  ILE B CD1 1 
ATOM   1316 N N   . ILE B 1 40  ? 20.648  -25.467 2.237   1.00 31.13 ? 40  ILE B N   1 
ATOM   1317 C CA  . ILE B 1 40  ? 19.703  -26.431 2.860   1.00 33.44 ? 40  ILE B CA  1 
ATOM   1318 C C   . ILE B 1 40  ? 18.328  -25.791 2.861   1.00 31.32 ? 40  ILE B C   1 
ATOM   1319 O O   . ILE B 1 40  ? 18.214  -24.689 3.417   1.00 30.55 ? 40  ILE B O   1 
ATOM   1320 C CB  . ILE B 1 40  ? 20.128  -26.820 4.286   1.00 40.14 ? 40  ILE B CB  1 
ATOM   1321 C CG1 . ILE B 1 40  ? 21.499  -27.507 4.300   1.00 37.89 ? 40  ILE B CG1 1 
ATOM   1322 C CG2 . ILE B 1 40  ? 19.020  -27.664 4.935   1.00 40.38 ? 40  ILE B CG2 1 
ATOM   1323 C CD1 . ILE B 1 40  ? 21.527  -28.805 3.535   1.00 39.24 ? 40  ILE B CD1 1 
ATOM   1324 N N   . PHE B 1 41  ? 17.350  -26.467 2.261   1.00 30.00 ? 41  PHE B N   1 
ATOM   1325 C CA  . PHE B 1 41  ? 15.907  -26.168 2.427   1.00 31.39 ? 41  PHE B CA  1 
ATOM   1326 C C   . PHE B 1 41  ? 15.357  -27.007 3.588   1.00 30.89 ? 41  PHE B C   1 
ATOM   1327 O O   . PHE B 1 41  ? 15.452  -28.244 3.519   1.00 29.93 ? 41  PHE B O   1 
ATOM   1328 C CB  . PHE B 1 41  ? 15.176  -26.466 1.124   1.00 33.32 ? 41  PHE B CB  1 
ATOM   1329 C CG  . PHE B 1 41  ? 15.246  -25.355 0.115   1.00 33.04 ? 41  PHE B CG  1 
ATOM   1330 C CD1 . PHE B 1 41  ? 16.371  -25.197 -0.681  1.00 31.37 ? 41  PHE B CD1 1 
ATOM   1331 C CD2 . PHE B 1 41  ? 14.198  -24.457 -0.005  1.00 31.31 ? 41  PHE B CD2 1 
ATOM   1332 C CE1 . PHE B 1 41  ? 16.440  -24.167 -1.595  1.00 32.82 ? 41  PHE B CE1 1 
ATOM   1333 C CE2 . PHE B 1 41  ? 14.258  -23.442 -0.947  1.00 35.00 ? 41  PHE B CE2 1 
ATOM   1334 C CZ  . PHE B 1 41  ? 15.378  -23.306 -1.740  1.00 34.54 ? 41  PHE B CZ  1 
ATOM   1335 N N   . ASP B 1 42  ? 14.883  -26.348 4.646   1.00 32.89 ? 42  ASP B N   1 
ATOM   1336 C CA  . ASP B 1 42  ? 14.162  -26.972 5.794   1.00 34.57 ? 42  ASP B CA  1 
ATOM   1337 C C   . ASP B 1 42  ? 13.227  -25.936 6.427   1.00 33.38 ? 42  ASP B C   1 
ATOM   1338 O O   . ASP B 1 42  ? 13.170  -24.785 5.945   1.00 28.00 ? 42  ASP B O   1 
ATOM   1339 C CB  . ASP B 1 42  ? 15.138  -27.519 6.839   1.00 34.51 ? 42  ASP B CB  1 
ATOM   1340 C CG  . ASP B 1 42  ? 15.966  -26.473 7.563   1.00 36.75 ? 42  ASP B CG  1 
ATOM   1341 O OD1 . ASP B 1 42  ? 15.596  -25.288 7.562   1.00 40.59 ? 42  ASP B OD1 1 
ATOM   1342 O OD2 . ASP B 1 42  ? 16.968  -26.856 8.145   1.00 42.79 ? 42  ASP B OD2 1 
ATOM   1343 N N   . GLN B 1 43  ? 12.565  -26.310 7.517   1.00 38.16 ? 43  GLN B N   1 
ATOM   1344 C CA  . GLN B 1 43  ? 11.550  -25.452 8.178   1.00 42.46 ? 43  GLN B CA  1 
ATOM   1345 C C   . GLN B 1 43  ? 12.109  -24.958 9.512   1.00 43.58 ? 43  GLN B C   1 
ATOM   1346 O O   . GLN B 1 43  ? 11.313  -24.622 10.402  1.00 48.19 ? 43  GLN B O   1 
ATOM   1347 C CB  . GLN B 1 43  ? 10.231  -26.208 8.292   1.00 44.76 ? 43  GLN B CB  1 
ATOM   1348 C CG  . GLN B 1 43  ? 9.619   -26.498 6.935   1.00 48.36 ? 43  GLN B CG  1 
ATOM   1349 C CD  . GLN B 1 43  ? 8.555   -27.561 7.002   1.00 54.25 ? 43  GLN B CD  1 
ATOM   1350 O OE1 . GLN B 1 43  ? 8.565   -28.534 6.252   1.00 58.71 ? 43  GLN B OE1 1 
ATOM   1351 N NE2 . GLN B 1 43  ? 7.629   -27.378 7.922   1.00 55.16 ? 43  GLN B NE2 1 
ATOM   1352 N N   . SER B 1 44  ? 13.431  -24.852 9.622   1.00 42.08 ? 44  SER B N   1 
ATOM   1353 C CA  . SER B 1 44  ? 14.092  -24.365 10.849  1.00 47.72 ? 44  SER B CA  1 
ATOM   1354 C C   . SER B 1 44  ? 14.704  -22.982 10.573  1.00 54.81 ? 44  SER B C   1 
ATOM   1355 O O   . SER B 1 44  ? 15.217  -22.764 9.445   1.00 57.98 ? 44  SER B O   1 
ATOM   1356 C CB  . SER B 1 44  ? 15.073  -25.370 11.391  1.00 48.92 ? 44  SER B CB  1 
ATOM   1357 O OG  . SER B 1 44  ? 16.397  -25.054 11.023  1.00 55.03 ? 44  SER B OG  1 
ATOM   1358 N N   . THR B 1 45  ? 14.556  -22.077 11.555  1.00 54.03 ? 45  THR B N   1 
ATOM   1359 C CA  . THR B 1 45  ? 15.170  -20.729 11.622  1.00 52.95 ? 45  THR B CA  1 
ATOM   1360 C C   . THR B 1 45  ? 16.613  -20.888 12.089  1.00 51.77 ? 45  THR B C   1 
ATOM   1361 O O   . THR B 1 45  ? 16.878  -21.198 13.250  1.00 50.22 ? 45  THR B O   1 
ATOM   1362 C CB  . THR B 1 45  ? 14.400  -19.792 12.560  1.00 53.22 ? 45  THR B CB  1 
ATOM   1363 O OG1 . THR B 1 45  ? 13.042  -19.716 12.119  1.00 52.10 ? 45  THR B OG1 1 
ATOM   1364 C CG2 . THR B 1 45  ? 15.021  -18.412 12.609  1.00 54.59 ? 45  THR B CG2 1 
ATOM   1365 N N   . PRO B 1 46  ? 17.598  -20.664 11.202  1.00 44.26 ? 46  PRO B N   1 
ATOM   1366 C CA  . PRO B 1 46  ? 18.995  -20.790 11.599  1.00 47.86 ? 46  PRO B CA  1 
ATOM   1367 C C   . PRO B 1 46  ? 19.408  -19.541 12.401  1.00 49.85 ? 46  PRO B C   1 
ATOM   1368 O O   . PRO B 1 46  ? 18.614  -18.644 12.596  1.00 51.48 ? 46  PRO B O   1 
ATOM   1369 C CB  . PRO B 1 46  ? 19.697  -20.918 10.234  1.00 45.32 ? 46  PRO B CB  1 
ATOM   1370 C CG  . PRO B 1 46  ? 18.858  -20.049 9.314   1.00 44.76 ? 46  PRO B CG  1 
ATOM   1371 C CD  . PRO B 1 46  ? 17.431  -20.181 9.822   1.00 43.94 ? 46  PRO B CD  1 
ATOM   1372 N N   . GLY B 1 47  ? 20.658  -19.491 12.836  1.00 55.56 ? 47  GLY B N   1 
ATOM   1373 C CA  . GLY B 1 47  ? 21.213  -18.318 13.534  1.00 58.65 ? 47  GLY B CA  1 
ATOM   1374 C C   . GLY B 1 47  ? 21.541  -17.205 12.561  1.00 55.37 ? 47  GLY B C   1 
ATOM   1375 O O   . GLY B 1 47  ? 21.292  -17.390 11.365  1.00 53.18 ? 47  GLY B O   1 
ATOM   1376 N N   . GLN B 1 48  ? 21.998  -16.066 13.088  1.00 51.93 ? 48  GLN B N   1 
ATOM   1377 C CA  . GLN B 1 48  ? 22.770  -15.020 12.374  1.00 53.50 ? 48  GLN B CA  1 
ATOM   1378 C C   . GLN B 1 48  ? 22.210  -14.768 10.961  1.00 46.61 ? 48  GLN B C   1 
ATOM   1379 O O   . GLN B 1 48  ? 22.999  -14.423 10.067  1.00 48.24 ? 48  GLN B O   1 
ATOM   1380 C CB  . GLN B 1 48  ? 24.244  -15.443 12.310  1.00 62.66 ? 48  GLN B CB  1 
ATOM   1381 C CG  . GLN B 1 48  ? 24.761  -16.159 13.560  1.00 63.39 ? 48  GLN B CG  1 
ATOM   1382 C CD  . GLN B 1 48  ? 25.525  -17.415 13.209  1.00 65.16 ? 48  GLN B CD  1 
ATOM   1383 O OE1 . GLN B 1 48  ? 25.444  -18.434 13.889  1.00 63.77 ? 48  GLN B OE1 1 
ATOM   1384 N NE2 . GLN B 1 48  ? 26.249  -17.365 12.103  1.00 73.92 ? 48  GLN B NE2 1 
ATOM   1385 N N   . ASP B 1 49  ? 20.900  -14.894 10.763  1.00 40.50 ? 49  ASP B N   1 
ATOM   1386 C CA  . ASP B 1 49  ? 20.242  -14.501 9.497   1.00 38.29 ? 49  ASP B CA  1 
ATOM   1387 C C   . ASP B 1 49  ? 20.776  -15.325 8.319   1.00 38.50 ? 49  ASP B C   1 
ATOM   1388 O O   . ASP B 1 49  ? 20.831  -14.803 7.184   1.00 36.33 ? 49  ASP B O   1 
ATOM   1389 C CB  . ASP B 1 49  ? 20.491  -13.018 9.262   1.00 41.59 ? 49  ASP B CB  1 
ATOM   1390 C CG  . ASP B 1 49  ? 19.647  -12.126 10.149  1.00 42.43 ? 49  ASP B CG  1 
ATOM   1391 O OD1 . ASP B 1 49  ? 18.475  -12.473 10.381  1.00 41.73 ? 49  ASP B OD1 1 
ATOM   1392 O OD2 . ASP B 1 49  ? 20.159  -11.073 10.547  1.00 44.68 ? 49  ASP B OD2 1 
ATOM   1393 N N   . ALA B 1 50  ? 21.131  -16.579 8.561   1.00 35.90 ? 50  ALA B N   1 
ATOM   1394 C CA  . ALA B 1 50  ? 21.596  -17.518 7.521   1.00 38.73 ? 50  ALA B CA  1 
ATOM   1395 C C   . ALA B 1 50  ? 20.458  -17.842 6.524   1.00 35.73 ? 50  ALA B C   1 
ATOM   1396 O O   . ALA B 1 50  ? 20.757  -18.478 5.491   1.00 38.78 ? 50  ALA B O   1 
ATOM   1397 C CB  . ALA B 1 50  ? 22.156  -18.757 8.198   1.00 37.74 ? 50  ALA B CB  1 
ATOM   1398 N N   . ASP B 1 51  ? 19.213  -17.432 6.798   1.00 29.56 ? 51  ASP B N   1 
ATOM   1399 C CA  . ASP B 1 51  ? 18.041  -17.661 5.904   1.00 30.01 ? 51  ASP B CA  1 
ATOM   1400 C C   . ASP B 1 51  ? 17.589  -16.362 5.217   1.00 28.21 ? 51  ASP B C   1 
ATOM   1401 O O   . ASP B 1 51  ? 16.464  -16.350 4.660   1.00 24.52 ? 51  ASP B O   1 
ATOM   1402 C CB  . ASP B 1 51  ? 16.860  -18.294 6.658   1.00 30.70 ? 51  ASP B CB  1 
ATOM   1403 C CG  . ASP B 1 51  ? 16.410  -17.525 7.884   1.00 33.77 ? 51  ASP B CG  1 
ATOM   1404 O OD1 . ASP B 1 51  ? 17.114  -16.562 8.277   1.00 36.14 ? 51  ASP B OD1 1 
ATOM   1405 O OD2 . ASP B 1 51  ? 15.366  -17.899 8.442   1.00 35.75 ? 51  ASP B OD2 1 
ATOM   1406 N N   . ARG B 1 52  ? 18.442  -15.333 5.195   1.00 29.17 ? 52  ARG B N   1 
ATOM   1407 C CA  . ARG B 1 52  ? 18.116  -13.992 4.642   1.00 29.96 ? 52  ARG B CA  1 
ATOM   1408 C C   . ARG B 1 52  ? 18.987  -13.748 3.428   1.00 28.49 ? 52  ARG B C   1 
ATOM   1409 O O   . ARG B 1 52  ? 20.231  -13.850 3.585   1.00 29.63 ? 52  ARG B O   1 
ATOM   1410 C CB  . ARG B 1 52  ? 18.394  -12.873 5.647   1.00 34.20 ? 52  ARG B CB  1 
ATOM   1411 C CG  . ARG B 1 52  ? 17.565  -12.986 6.907   1.00 35.91 ? 52  ARG B CG  1 
ATOM   1412 C CD  . ARG B 1 52  ? 16.108  -12.674 6.694   1.00 42.55 ? 52  ARG B CD  1 
ATOM   1413 N NE  . ARG B 1 52  ? 15.334  -13.198 7.813   1.00 47.11 ? 52  ARG B NE  1 
ATOM   1414 C CZ  . ARG B 1 52  ? 14.018  -13.102 7.941   1.00 52.71 ? 52  ARG B CZ  1 
ATOM   1415 N NH1 . ARG B 1 52  ? 13.283  -12.475 7.038   1.00 52.63 ? 52  ARG B NH1 1 
ATOM   1416 N NH2 . ARG B 1 52  ? 13.435  -13.651 8.987   1.00 64.88 ? 52  ARG B NH2 1 
ATOM   1417 N N   . TRP B 1 53  ? 18.365  -13.477 2.279   1.00 29.51 ? 53  TRP B N   1 
ATOM   1418 C CA  . TRP B 1 53  ? 19.087  -13.316 0.984   1.00 30.63 ? 53  TRP B CA  1 
ATOM   1419 C C   . TRP B 1 53  ? 18.935  -11.891 0.416   1.00 31.53 ? 53  TRP B C   1 
ATOM   1420 O O   . TRP B 1 53  ? 18.026  -11.128 0.824   1.00 26.75 ? 53  TRP B O   1 
ATOM   1421 C CB  . TRP B 1 53  ? 18.649  -14.402 -0.009  1.00 32.51 ? 53  TRP B CB  1 
ATOM   1422 C CG  . TRP B 1 53  ? 18.827  -15.808 0.500   1.00 30.47 ? 53  TRP B CG  1 
ATOM   1423 C CD1 . TRP B 1 53  ? 17.989  -16.485 1.339   1.00 32.85 ? 53  TRP B CD1 1 
ATOM   1424 C CD2 . TRP B 1 53  ? 19.892  -16.722 0.182   1.00 26.98 ? 53  TRP B CD2 1 
ATOM   1425 N NE1 . TRP B 1 53  ? 18.464  -17.752 1.575   1.00 32.83 ? 53  TRP B NE1 1 
ATOM   1426 C CE2 . TRP B 1 53  ? 19.645  -17.918 0.895   1.00 31.04 ? 53  TRP B CE2 1 
ATOM   1427 C CE3 . TRP B 1 53  ? 21.059  -16.630 -0.574  1.00 28.71 ? 53  TRP B CE3 1 
ATOM   1428 C CZ2 . TRP B 1 53  ? 20.507  -19.018 0.838   1.00 28.70 ? 53  TRP B CZ2 1 
ATOM   1429 C CZ3 . TRP B 1 53  ? 21.911  -17.711 -0.627  1.00 28.89 ? 53  TRP B CZ3 1 
ATOM   1430 C CH2 . TRP B 1 53  ? 21.641  -18.886 0.069   1.00 27.61 ? 53  TRP B CH2 1 
ATOM   1431 N N   . LEU B 1 54  ? 19.881  -11.524 -0.437  1.00 32.89 ? 54  LEU B N   1 
ATOM   1432 C CA  . LEU B 1 54  ? 19.869  -10.283 -1.247  1.00 33.38 ? 54  LEU B CA  1 
ATOM   1433 C C   . LEU B 1 54  ? 20.120  -10.681 -2.712  1.00 32.81 ? 54  LEU B C   1 
ATOM   1434 O O   . LEU B 1 54  ? 21.193  -11.271 -3.030  1.00 29.83 ? 54  LEU B O   1 
ATOM   1435 C CB  . LEU B 1 54  ? 20.928  -9.327  -0.676  1.00 32.46 ? 54  LEU B CB  1 
ATOM   1436 C CG  . LEU B 1 54  ? 20.982  -7.913  -1.258  1.00 33.41 ? 54  LEU B CG  1 
ATOM   1437 C CD1 . LEU B 1 54  ? 19.654  -7.191  -1.143  1.00 32.78 ? 54  LEU B CD1 1 
ATOM   1438 C CD2 . LEU B 1 54  ? 22.071  -7.102  -0.576  1.00 37.27 ? 54  LEU B CD2 1 
ATOM   1439 N N   . ILE B 1 55  ? 19.123  -10.403 -3.558  1.00 34.00 ? 55  ILE B N   1 
ATOM   1440 C CA  . ILE B 1 55  ? 19.148  -10.593 -5.039  1.00 36.70 ? 55  ILE B CA  1 
ATOM   1441 C C   . ILE B 1 55  ? 19.531  -9.260  -5.714  1.00 34.90 ? 55  ILE B C   1 
ATOM   1442 O O   . ILE B 1 55  ? 18.844  -8.257  -5.507  1.00 36.86 ? 55  ILE B O   1 
ATOM   1443 C CB  . ILE B 1 55  ? 17.786  -11.120 -5.529  1.00 39.03 ? 55  ILE B CB  1 
ATOM   1444 C CG1 . ILE B 1 55  ? 17.291  -12.291 -4.674  1.00 40.03 ? 55  ILE B CG1 1 
ATOM   1445 C CG2 . ILE B 1 55  ? 17.856  -11.484 -7.010  1.00 39.64 ? 55  ILE B CG2 1 
ATOM   1446 C CD1 . ILE B 1 55  ? 15.886  -12.714 -5.001  1.00 43.64 ? 55  ILE B CD1 1 
ATOM   1447 N N   . HIS B 1 56  ? 20.603  -9.267  -6.496  1.00 32.16 ? 56  HIS B N   1 
ATOM   1448 C CA  . HIS B 1 56  ? 21.091  -8.122  -7.302  1.00 31.33 ? 56  HIS B CA  1 
ATOM   1449 C C   . HIS B 1 56  ? 21.116  -8.503  -8.772  1.00 28.43 ? 56  HIS B C   1 
ATOM   1450 O O   . HIS B 1 56  ? 21.292  -9.668  -9.078  1.00 25.90 ? 56  HIS B O   1 
ATOM   1451 C CB  . HIS B 1 56  ? 22.504  -7.705  -6.887  1.00 30.00 ? 56  HIS B CB  1 
ATOM   1452 C CG  . HIS B 1 56  ? 22.505  -6.978  -5.597  1.00 31.27 ? 56  HIS B CG  1 
ATOM   1453 N ND1 . HIS B 1 56  ? 21.330  -6.487  -5.048  1.00 30.67 ? 56  HIS B ND1 1 
ATOM   1454 C CD2 . HIS B 1 56  ? 23.514  -6.618  -4.774  1.00 31.34 ? 56  HIS B CD2 1 
ATOM   1455 C CE1 . HIS B 1 56  ? 21.619  -5.867  -3.924  1.00 32.24 ? 56  HIS B CE1 1 
ATOM   1456 N NE2 . HIS B 1 56  ? 22.963  -5.921  -3.733  1.00 29.50 ? 56  HIS B NE2 1 
ATOM   1457 N N   . ASN B 1 57  ? 20.930  -7.506  -9.620  1.00 33.24 ? 57  ASN B N   1 
ATOM   1458 C CA  . ASN B 1 57  ? 21.268  -7.546  -11.055 1.00 34.45 ? 57  ASN B CA  1 
ATOM   1459 C C   . ASN B 1 57  ? 22.732  -7.927  -11.143 1.00 37.60 ? 57  ASN B C   1 
ATOM   1460 O O   . ASN B 1 57  ? 23.525  -7.453  -10.318 1.00 37.94 ? 57  ASN B O   1 
ATOM   1461 C CB  . ASN B 1 57  ? 21.020  -6.200  -11.735 1.00 36.18 ? 57  ASN B CB  1 
ATOM   1462 C CG  . ASN B 1 57  ? 19.546  -5.888  -11.863 1.00 39.97 ? 57  ASN B CG  1 
ATOM   1463 O OD1 . ASN B 1 57  ? 19.054  -4.944  -11.252 1.00 50.87 ? 57  ASN B OD1 1 
ATOM   1464 N ND2 . ASN B 1 57  ? 18.820  -6.689  -12.616 1.00 38.25 ? 57  ASN B ND2 1 
ATOM   1465 N N   . TYR B 1 58  ? 23.066  -8.782  -12.099 1.00 41.90 ? 58  TYR B N   1 
ATOM   1466 C CA  . TYR B 1 58  ? 24.469  -9.023  -12.520 1.00 42.32 ? 58  TYR B CA  1 
ATOM   1467 C C   . TYR B 1 58  ? 24.463  -9.328  -14.019 1.00 40.25 ? 58  TYR B C   1 
ATOM   1468 O O   . TYR B 1 58  ? 23.937  -10.397 -14.388 1.00 39.44 ? 58  TYR B O   1 
ATOM   1469 C CB  . TYR B 1 58  ? 25.121  -10.123 -11.670 1.00 39.44 ? 58  TYR B CB  1 
ATOM   1470 C CG  . TYR B 1 58  ? 26.507  -10.507 -12.134 1.00 41.28 ? 58  TYR B CG  1 
ATOM   1471 C CD1 . TYR B 1 58  ? 27.603  -9.669  -11.936 1.00 39.30 ? 58  TYR B CD1 1 
ATOM   1472 C CD2 . TYR B 1 58  ? 26.715  -11.689 -12.827 1.00 40.05 ? 58  TYR B CD2 1 
ATOM   1473 C CE1 . TYR B 1 58  ? 28.868  -10.005 -12.392 1.00 34.86 ? 58  TYR B CE1 1 
ATOM   1474 C CE2 . TYR B 1 58  ? 27.973  -12.049 -13.275 1.00 40.57 ? 58  TYR B CE2 1 
ATOM   1475 C CZ  . TYR B 1 58  ? 29.056  -11.211 -13.053 1.00 41.42 ? 58  TYR B CZ  1 
ATOM   1476 O OH  . TYR B 1 58  ? 30.283  -11.614 -13.514 1.00 44.03 ? 58  TYR B OH  1 
ATOM   1477 N N   . LEU B 1 59  ? 25.002  -8.406  -14.839 1.00 43.35 ? 59  LEU B N   1 
ATOM   1478 C CA  . LEU B 1 59  ? 25.046  -8.498  -16.330 1.00 38.12 ? 59  LEU B CA  1 
ATOM   1479 C C   . LEU B 1 59  ? 23.628  -8.756  -16.854 1.00 36.54 ? 59  LEU B C   1 
ATOM   1480 O O   . LEU B 1 59  ? 22.773  -7.954  -16.540 1.00 37.80 ? 59  LEU B O   1 
ATOM   1481 C CB  . LEU B 1 59  ? 26.037  -9.602  -16.718 1.00 39.18 ? 59  LEU B CB  1 
ATOM   1482 C CG  . LEU B 1 59  ? 27.449  -9.410  -16.153 1.00 38.81 ? 59  LEU B CG  1 
ATOM   1483 C CD1 . LEU B 1 59  ? 28.316  -10.644 -16.396 1.00 39.66 ? 59  LEU B CD1 1 
ATOM   1484 C CD2 . LEU B 1 59  ? 28.114  -8.168  -16.723 1.00 35.80 ? 59  LEU B CD2 1 
ATOM   1485 N N   . ASP B 1 60  ? 23.350  -9.857  -17.562 1.00 37.67 ? 60  ASP B N   1 
ATOM   1486 C CA  . ASP B 1 60  ? 21.985  -10.092 -18.129 1.00 36.15 ? 60  ASP B CA  1 
ATOM   1487 C C   . ASP B 1 60  ? 21.092  -10.817 -17.120 1.00 36.74 ? 60  ASP B C   1 
ATOM   1488 O O   . ASP B 1 60  ? 19.913  -11.007 -17.423 1.00 35.94 ? 60  ASP B O   1 
ATOM   1489 C CB  . ASP B 1 60  ? 22.004  -10.871 -19.446 1.00 35.44 ? 60  ASP B CB  1 
ATOM   1490 C CG  . ASP B 1 60  ? 22.980  -12.024 -19.488 1.00 38.05 ? 60  ASP B CG  1 
ATOM   1491 O OD1 . ASP B 1 60  ? 23.940  -12.000 -18.700 1.00 39.44 ? 60  ASP B OD1 1 
ATOM   1492 O OD2 . ASP B 1 60  ? 22.763  -12.954 -20.296 1.00 42.70 ? 60  ASP B OD2 1 
ATOM   1493 N N   . GLY B 1 61  ? 21.619  -11.203 -15.958 1.00 34.79 ? 61  GLY B N   1 
ATOM   1494 C CA  . GLY B 1 61  ? 20.833  -11.949 -14.966 1.00 36.07 ? 61  GLY B CA  1 
ATOM   1495 C C   . GLY B 1 61  ? 21.005  -11.380 -13.580 1.00 35.59 ? 61  GLY B C   1 
ATOM   1496 O O   . GLY B 1 61  ? 21.176  -10.170 -13.459 1.00 37.23 ? 61  GLY B O   1 
ATOM   1497 N N   . TYR B 1 62  ? 21.055  -12.267 -12.585 1.00 36.10 ? 62  TYR B N   1 
ATOM   1498 C CA  . TYR B 1 62  ? 20.976  -11.964 -11.140 1.00 34.40 ? 62  TYR B CA  1 
ATOM   1499 C C   . TYR B 1 62  ? 22.040  -12.761 -10.411 1.00 32.43 ? 62  TYR B C   1 
ATOM   1500 O O   . TYR B 1 62  ? 22.407  -13.869 -10.867 1.00 35.05 ? 62  TYR B O   1 
ATOM   1501 C CB  . TYR B 1 62  ? 19.590  -12.336 -10.619 1.00 34.47 ? 62  TYR B CB  1 
ATOM   1502 C CG  . TYR B 1 62  ? 18.498  -11.670 -11.401 1.00 39.13 ? 62  TYR B CG  1 
ATOM   1503 C CD1 . TYR B 1 62  ? 17.849  -12.331 -12.438 1.00 40.78 ? 62  TYR B CD1 1 
ATOM   1504 C CD2 . TYR B 1 62  ? 18.163  -10.350 -11.154 1.00 40.44 ? 62  TYR B CD2 1 
ATOM   1505 C CE1 . TYR B 1 62  ? 16.879  -11.696 -13.196 1.00 43.18 ? 62  TYR B CE1 1 
ATOM   1506 C CE2 . TYR B 1 62  ? 17.180  -9.707  -11.893 1.00 41.83 ? 62  TYR B CE2 1 
ATOM   1507 C CZ  . TYR B 1 62  ? 16.535  -10.382 -12.913 1.00 44.99 ? 62  TYR B CZ  1 
ATOM   1508 O OH  . TYR B 1 62  ? 15.551  -9.749  -13.610 1.00 47.80 ? 62  TYR B OH  1 
ATOM   1509 N N   . LYS B 1 63  ? 22.474  -12.224 -9.285  1.00 32.06 ? 63  LYS B N   1 
ATOM   1510 C CA  . LYS B 1 63  ? 23.354  -12.926 -8.320  1.00 34.65 ? 63  LYS B CA  1 
ATOM   1511 C C   . LYS B 1 63  ? 22.608  -12.989 -6.972  1.00 33.40 ? 63  LYS B C   1 
ATOM   1512 O O   . LYS B 1 63  ? 21.798  -12.095 -6.706  1.00 30.63 ? 63  LYS B O   1 
ATOM   1513 C CB  . LYS B 1 63  ? 24.704  -12.202 -8.259  1.00 37.59 ? 63  LYS B CB  1 
ATOM   1514 C CG  . LYS B 1 63  ? 24.603  -10.686 -8.134  1.00 36.79 ? 63  LYS B CG  1 
ATOM   1515 C CD  . LYS B 1 63  ? 25.818  -10.087 -7.481  1.00 42.58 ? 63  LYS B CD  1 
ATOM   1516 C CE  . LYS B 1 63  ? 26.254  -8.779  -8.084  1.00 45.10 ? 63  LYS B CE  1 
ATOM   1517 N NZ  . LYS B 1 63  ? 27.407  -8.258  -7.327  1.00 48.18 ? 63  LYS B NZ  1 
ATOM   1518 N N   . ILE B 1 64  ? 22.839  -14.040 -6.188  1.00 32.73 ? 64  ILE B N   1 
ATOM   1519 C CA  . ILE B 1 64  ? 21.991  -14.394 -5.013  1.00 35.13 ? 64  ILE B CA  1 
ATOM   1520 C C   . ILE B 1 64  ? 22.958  -14.574 -3.842  1.00 35.51 ? 64  ILE B C   1 
ATOM   1521 O O   . ILE B 1 64  ? 23.790  -15.507 -3.866  1.00 32.52 ? 64  ILE B O   1 
ATOM   1522 C CB  . ILE B 1 64  ? 21.109  -15.642 -5.272  1.00 33.62 ? 64  ILE B CB  1 
ATOM   1523 C CG1 . ILE B 1 64  ? 20.153  -15.476 -6.456  1.00 35.26 ? 64  ILE B CG1 1 
ATOM   1524 C CG2 . ILE B 1 64  ? 20.340  -16.006 -4.026  1.00 34.45 ? 64  ILE B CG2 1 
ATOM   1525 C CD1 . ILE B 1 64  ? 19.338  -16.719 -6.773  1.00 35.99 ? 64  ILE B CD1 1 
ATOM   1526 N N   . PHE B 1 65  ? 22.863  -13.667 -2.878  1.00 35.89 ? 65  PHE B N   1 
ATOM   1527 C CA  . PHE B 1 65  ? 23.849  -13.486 -1.791  1.00 31.99 ? 65  PHE B CA  1 
ATOM   1528 C C   . PHE B 1 65  ? 23.170  -13.767 -0.454  1.00 30.61 ? 65  PHE B C   1 
ATOM   1529 O O   . PHE B 1 65  ? 22.062  -13.274 -0.251  1.00 29.02 ? 65  PHE B O   1 
ATOM   1530 C CB  . PHE B 1 65  ? 24.398  -12.075 -1.880  1.00 30.56 ? 65  PHE B CB  1 
ATOM   1531 C CG  . PHE B 1 65  ? 25.292  -11.680 -0.748  1.00 31.01 ? 65  PHE B CG  1 
ATOM   1532 C CD1 . PHE B 1 65  ? 26.653  -11.903 -0.817  1.00 31.19 ? 65  PHE B CD1 1 
ATOM   1533 C CD2 . PHE B 1 65  ? 24.770  -11.029 0.367   1.00 32.48 ? 65  PHE B CD2 1 
ATOM   1534 C CE1 . PHE B 1 65  ? 27.481  -11.503 0.226   1.00 31.53 ? 65  PHE B CE1 1 
ATOM   1535 C CE2 . PHE B 1 65  ? 25.605  -10.603 1.389   1.00 30.42 ? 65  PHE B CE2 1 
ATOM   1536 C CZ  . PHE B 1 65  ? 26.954  -10.863 1.326   1.00 30.11 ? 65  PHE B CZ  1 
ATOM   1537 N N   . ASN B 1 66  ? 23.823  -14.563 0.400   1.00 34.24 ? 66  ASN B N   1 
ATOM   1538 C CA  . ASN B 1 66  ? 23.363  -14.874 1.786   1.00 34.35 ? 66  ASN B CA  1 
ATOM   1539 C C   . ASN B 1 66  ? 23.921  -13.816 2.755   1.00 32.66 ? 66  ASN B C   1 
ATOM   1540 O O   . ASN B 1 66  ? 25.153  -13.775 2.995   1.00 30.06 ? 66  ASN B O   1 
ATOM   1541 C CB  . ASN B 1 66  ? 23.712  -16.302 2.224   1.00 29.90 ? 66  ASN B CB  1 
ATOM   1542 C CG  . ASN B 1 66  ? 22.982  -16.682 3.498   1.00 30.41 ? 66  ASN B CG  1 
ATOM   1543 O OD1 . ASN B 1 66  ? 23.320  -16.208 4.592   1.00 26.02 ? 66  ASN B OD1 1 
ATOM   1544 N ND2 . ASN B 1 66  ? 21.932  -17.478 3.358   1.00 30.54 ? 66  ASN B ND2 1 
ATOM   1545 N N   . MET B 1 67  ? 23.035  -12.992 3.301   1.00 34.40 ? 67  MET B N   1 
ATOM   1546 C CA  . MET B 1 67  ? 23.389  -11.944 4.290   1.00 35.30 ? 67  MET B CA  1 
ATOM   1547 C C   . MET B 1 67  ? 24.073  -12.607 5.502   1.00 33.15 ? 67  MET B C   1 
ATOM   1548 O O   . MET B 1 67  ? 25.099  -12.062 6.011   1.00 33.44 ? 67  MET B O   1 
ATOM   1549 C CB  . MET B 1 67  ? 22.131  -11.192 4.739   1.00 37.89 ? 67  MET B CB  1 
ATOM   1550 C CG  . MET B 1 67  ? 21.398  -10.471 3.614   1.00 39.75 ? 67  MET B CG  1 
ATOM   1551 S SD  . MET B 1 67  ? 22.338  -9.085  2.994   1.00 45.62 ? 67  MET B SD  1 
ATOM   1552 C CE  . MET B 1 67  ? 22.000  -7.904  4.299   1.00 35.49 ? 67  MET B CE  1 
ATOM   1553 N N   . GLY B 1 68  ? 23.517  -13.709 6.005   1.00 30.20 ? 68  GLY B N   1 
ATOM   1554 C CA  . GLY B 1 68  ? 24.136  -14.442 7.123   1.00 30.28 ? 68  GLY B CA  1 
ATOM   1555 C C   . GLY B 1 68  ? 25.584  -14.797 6.799   1.00 33.50 ? 68  GLY B C   1 
ATOM   1556 O O   . GLY B 1 68  ? 26.467  -14.293 7.526   1.00 31.93 ? 68  GLY B O   1 
ATOM   1557 N N   . SER B 1 69  ? 25.832  -15.542 5.699   1.00 31.34 ? 69  SER B N   1 
ATOM   1558 C CA  . SER B 1 69  ? 27.113  -16.255 5.394   1.00 33.46 ? 69  SER B CA  1 
ATOM   1559 C C   . SER B 1 69  ? 28.089  -15.442 4.524   1.00 33.00 ? 69  SER B C   1 
ATOM   1560 O O   . SER B 1 69  ? 29.283  -15.808 4.486   1.00 35.84 ? 69  SER B O   1 
ATOM   1561 C CB  . SER B 1 69  ? 26.847  -17.609 4.746   1.00 36.23 ? 69  SER B CB  1 
ATOM   1562 O OG  . SER B 1 69  ? 26.183  -17.483 3.482   1.00 33.70 ? 69  SER B OG  1 
ATOM   1563 N N   . ASN B 1 70  ? 27.610  -14.395 3.858   1.00 32.55 ? 70  ASN B N   1 
ATOM   1564 C CA  . ASN B 1 70  ? 28.348  -13.607 2.833   1.00 35.21 ? 70  ASN B CA  1 
ATOM   1565 C C   . ASN B 1 70  ? 28.775  -14.570 1.724   1.00 31.90 ? 70  ASN B C   1 
ATOM   1566 O O   . ASN B 1 70  ? 29.778  -14.322 1.079   1.00 32.37 ? 70  ASN B O   1 
ATOM   1567 C CB  . ASN B 1 70  ? 29.507  -12.780 3.420   1.00 35.85 ? 70  ASN B CB  1 
ATOM   1568 C CG  . ASN B 1 70  ? 29.045  -11.723 4.406   1.00 40.08 ? 70  ASN B CG  1 
ATOM   1569 O OD1 . ASN B 1 70  ? 28.552  -12.048 5.486   1.00 37.60 ? 70  ASN B OD1 1 
ATOM   1570 N ND2 . ASN B 1 70  ? 29.196  -10.450 4.050   1.00 42.07 ? 70  ASN B ND2 1 
ATOM   1571 N N   . ASN B 1 71  ? 28.001  -15.626 1.502   1.00 30.92 ? 71  ASN B N   1 
ATOM   1572 C CA  . ASN B 1 71  ? 28.225  -16.595 0.401   1.00 29.10 ? 71  ASN B CA  1 
ATOM   1573 C C   . ASN B 1 71  ? 27.337  -16.244 -0.800  1.00 30.96 ? 71  ASN B C   1 
ATOM   1574 O O   . ASN B 1 71  ? 26.200  -15.736 -0.607  1.00 34.39 ? 71  ASN B O   1 
ATOM   1575 C CB  . ASN B 1 71  ? 27.977  -18.031 0.866   1.00 27.47 ? 71  ASN B CB  1 
ATOM   1576 C CG  . ASN B 1 71  ? 29.110  -18.605 1.686   1.00 25.87 ? 71  ASN B CG  1 
ATOM   1577 O OD1 . ASN B 1 71  ? 30.244  -18.133 1.625   1.00 28.56 ? 71  ASN B OD1 1 
ATOM   1578 N ND2 . ASN B 1 71  ? 28.827  -19.647 2.440   1.00 24.00 ? 71  ASN B ND2 1 
ATOM   1579 N N   . TRP B 1 72  ? 27.816  -16.557 -2.001  1.00 27.37 ? 72  TRP B N   1 
ATOM   1580 C CA  . TRP B 1 72  ? 27.048  -16.444 -3.256  1.00 29.20 ? 72  TRP B CA  1 
ATOM   1581 C C   . TRP B 1 72  ? 26.481  -17.822 -3.616  1.00 29.69 ? 72  TRP B C   1 
ATOM   1582 O O   . TRP B 1 72  ? 27.291  -18.782 -3.581  1.00 27.30 ? 72  TRP B O   1 
ATOM   1583 C CB  . TRP B 1 72  ? 27.967  -15.933 -4.362  1.00 29.22 ? 72  TRP B CB  1 
ATOM   1584 C CG  . TRP B 1 72  ? 28.536  -14.588 -4.069  1.00 31.21 ? 72  TRP B CG  1 
ATOM   1585 C CD1 . TRP B 1 72  ? 29.763  -14.293 -3.540  1.00 30.81 ? 72  TRP B CD1 1 
ATOM   1586 C CD2 . TRP B 1 72  ? 27.869  -13.336 -4.280  1.00 32.14 ? 72  TRP B CD2 1 
ATOM   1587 N NE1 . TRP B 1 72  ? 29.914  -12.940 -3.446  1.00 31.86 ? 72  TRP B NE1 1 
ATOM   1588 C CE2 . TRP B 1 72  ? 28.776  -12.324 -3.895  1.00 33.11 ? 72  TRP B CE2 1 
ATOM   1589 C CE3 . TRP B 1 72  ? 26.624  -12.986 -4.801  1.00 30.66 ? 72  TRP B CE3 1 
ATOM   1590 C CZ2 . TRP B 1 72  ? 28.449  -10.974 -3.971  1.00 32.38 ? 72  TRP B CZ2 1 
ATOM   1591 C CZ3 . TRP B 1 72  ? 26.307  -11.658 -4.891  1.00 33.00 ? 72  TRP B CZ3 1 
ATOM   1592 C CH2 . TRP B 1 72  ? 27.207  -10.669 -4.487  1.00 34.83 ? 72  TRP B CH2 1 
ATOM   1593 N N   . ALA B 1 73  ? 25.206  -17.906 -4.035  1.00 26.83 ? 73  ALA B N   1 
ATOM   1594 C CA  . ALA B 1 73  ? 24.593  -19.160 -4.558  1.00 29.86 ? 73  ALA B CA  1 
ATOM   1595 C C   . ALA B 1 73  ? 25.235  -19.532 -5.903  1.00 28.00 ? 73  ALA B C   1 
ATOM   1596 O O   . ALA B 1 73  ? 25.298  -18.688 -6.810  1.00 29.89 ? 73  ALA B O   1 
ATOM   1597 C CB  . ALA B 1 73  ? 23.084  -19.043 -4.655  1.00 30.56 ? 73  ALA B CB  1 
ATOM   1598 N N   . SER B 1 74  ? 25.736  -20.757 -6.017  1.00 32.57 ? 74  SER B N   1 
ATOM   1599 C CA  . SER B 1 74  ? 26.724  -21.188 -7.044  1.00 31.13 ? 74  SER B CA  1 
ATOM   1600 C C   . SER B 1 74  ? 26.570  -22.678 -7.356  1.00 30.43 ? 74  SER B C   1 
ATOM   1601 O O   . SER B 1 74  ? 26.579  -23.485 -6.434  1.00 33.12 ? 74  SER B O   1 
ATOM   1602 C CB  . SER B 1 74  ? 28.113  -20.893 -6.542  1.00 33.07 ? 74  SER B CB  1 
ATOM   1603 O OG  . SER B 1 74  ? 29.081  -21.128 -7.560  1.00 34.20 ? 74  SER B OG  1 
ATOM   1604 N N   . VAL B 1 75  ? 26.466  -23.048 -8.623  1.00 34.85 ? 75  VAL B N   1 
ATOM   1605 C CA  . VAL B 1 75  ? 26.605  -24.473 -9.035  1.00 36.75 ? 75  VAL B CA  1 
ATOM   1606 C C   . VAL B 1 75  ? 28.040  -24.907 -8.705  1.00 37.31 ? 75  VAL B C   1 
ATOM   1607 O O   . VAL B 1 75  ? 28.966  -24.152 -9.010  1.00 34.09 ? 75  VAL B O   1 
ATOM   1608 C CB  . VAL B 1 75  ? 26.287  -24.711 -10.524 1.00 40.52 ? 75  VAL B CB  1 
ATOM   1609 C CG1 . VAL B 1 75  ? 27.250  -23.979 -11.445 1.00 41.97 ? 75  VAL B CG1 1 
ATOM   1610 C CG2 . VAL B 1 75  ? 26.299  -26.203 -10.851 1.00 41.45 ? 75  VAL B CG2 1 
ATOM   1611 N N   . SER B 1 76  ? 28.188  -26.082 -8.089  1.00 36.15 ? 76  SER B N   1 
ATOM   1612 C CA  . SER B 1 76  ? 29.461  -26.795 -7.840  1.00 34.88 ? 76  SER B CA  1 
ATOM   1613 C C   . SER B 1 76  ? 29.357  -28.228 -8.403  1.00 36.37 ? 76  SER B C   1 
ATOM   1614 O O   . SER B 1 76  ? 28.465  -28.470 -9.239  1.00 33.65 ? 76  SER B O   1 
ATOM   1615 C CB  . SER B 1 76  ? 29.737  -26.790 -6.372  1.00 36.02 ? 76  SER B CB  1 
ATOM   1616 O OG  . SER B 1 76  ? 31.048  -27.248 -6.105  1.00 39.56 ? 76  SER B OG  1 
ATOM   1617 N N   . ARG B 1 77  ? 30.214  -29.129 -7.914  1.00 32.65 ? 77  ARG B N   1 
ATOM   1618 C CA  . ARG B 1 77  ? 30.241  -30.587 -8.175  1.00 34.11 ? 77  ARG B CA  1 
ATOM   1619 C C   . ARG B 1 77  ? 28.834  -31.204 -8.178  1.00 38.22 ? 77  ARG B C   1 
ATOM   1620 O O   . ARG B 1 77  ? 28.030  -30.907 -7.251  1.00 36.80 ? 77  ARG B O   1 
ATOM   1621 C CB  . ARG B 1 77  ? 31.061  -31.303 -7.096  1.00 36.24 ? 77  ARG B CB  1 
ATOM   1622 C CG  . ARG B 1 77  ? 32.526  -30.900 -7.010  1.00 41.32 ? 77  ARG B CG  1 
ATOM   1623 C CD  . ARG B 1 77  ? 33.157  -30.812 -8.396  1.00 47.60 ? 77  ARG B CD  1 
ATOM   1624 N NE  . ARG B 1 77  ? 34.533  -31.267 -8.402  1.00 51.39 ? 77  ARG B NE  1 
ATOM   1625 C CZ  . ARG B 1 77  ? 35.548  -30.630 -7.826  1.00 56.12 ? 77  ARG B CZ  1 
ATOM   1626 N NH1 . ARG B 1 77  ? 36.758  -31.158 -7.902  1.00 61.31 ? 77  ARG B NH1 1 
ATOM   1627 N NH2 . ARG B 1 77  ? 35.367  -29.493 -7.167  1.00 52.84 ? 77  ARG B NH2 1 
ATOM   1628 N N   . GLY B 1 78  ? 28.604  -32.110 -9.142  1.00 34.93 ? 78  GLY B N   1 
ATOM   1629 C CA  . GLY B 1 78  ? 27.383  -32.915 -9.305  1.00 33.14 ? 78  GLY B CA  1 
ATOM   1630 C C   . GLY B 1 78  ? 26.199  -32.051 -9.655  1.00 34.42 ? 78  GLY B C   1 
ATOM   1631 O O   . GLY B 1 78  ? 25.062  -32.551 -9.559  1.00 41.43 ? 78  GLY B O   1 
ATOM   1632 N N   . ASN B 1 79  ? 26.464  -30.793 -10.020 1.00 33.33 ? 79  ASN B N   1 
ATOM   1633 C CA  . ASN B 1 79  ? 25.446  -29.738 -10.262 1.00 33.28 ? 79  ASN B CA  1 
ATOM   1634 C C   . ASN B 1 79  ? 24.622  -29.521 -8.991  1.00 29.82 ? 79  ASN B C   1 
ATOM   1635 O O   . ASN B 1 79  ? 23.459  -29.167 -9.098  1.00 28.19 ? 79  ASN B O   1 
ATOM   1636 C CB  . ASN B 1 79  ? 24.584  -30.054 -11.485 1.00 35.74 ? 79  ASN B CB  1 
ATOM   1637 C CG  . ASN B 1 79  ? 25.373  -29.958 -12.761 1.00 36.64 ? 79  ASN B CG  1 
ATOM   1638 O OD1 . ASN B 1 79  ? 25.412  -30.914 -13.517 1.00 44.29 ? 79  ASN B OD1 1 
ATOM   1639 N ND2 . ASN B 1 79  ? 26.057  -28.849 -12.965 1.00 39.56 ? 79  ASN B ND2 1 
ATOM   1640 N N   . THR B 1 80  ? 25.246  -29.699 -7.832  1.00 31.68 ? 80  THR B N   1 
ATOM   1641 C CA  . THR B 1 80  ? 24.734  -29.268 -6.514  1.00 30.56 ? 80  THR B CA  1 
ATOM   1642 C C   . THR B 1 80  ? 24.870  -27.737 -6.412  1.00 30.34 ? 80  THR B C   1 
ATOM   1643 O O   . THR B 1 80  ? 25.918  -27.194 -6.783  1.00 29.76 ? 80  THR B O   1 
ATOM   1644 C CB  . THR B 1 80  ? 25.455  -30.069 -5.418  1.00 31.76 ? 80  THR B CB  1 
ATOM   1645 O OG1 . THR B 1 80  ? 25.202  -31.457 -5.647  1.00 32.77 ? 80  THR B OG1 1 
ATOM   1646 C CG2 . THR B 1 80  ? 24.998  -29.707 -4.019  1.00 33.44 ? 80  THR B CG2 1 
ATOM   1647 N N   . VAL B 1 81  ? 23.853  -27.066 -5.889  1.00 29.69 ? 81  VAL B N   1 
ATOM   1648 C CA  . VAL B 1 81  ? 23.896  -25.605 -5.592  1.00 29.11 ? 81  VAL B CA  1 
ATOM   1649 C C   . VAL B 1 81  ? 24.395  -25.384 -4.148  1.00 29.42 ? 81  VAL B C   1 
ATOM   1650 O O   . VAL B 1 81  ? 23.752  -25.870 -3.174  1.00 26.54 ? 81  VAL B O   1 
ATOM   1651 C CB  . VAL B 1 81  ? 22.538  -24.930 -5.842  1.00 29.62 ? 81  VAL B CB  1 
ATOM   1652 C CG1 . VAL B 1 81  ? 22.694  -23.411 -5.842  1.00 34.00 ? 81  VAL B CG1 1 
ATOM   1653 C CG2 . VAL B 1 81  ? 21.897  -25.376 -7.140  1.00 27.90 ? 81  VAL B CG2 1 
ATOM   1654 N N   . LEU B 1 82  ? 25.524  -24.679 -4.025  1.00 31.27 ? 82  LEU B N   1 
ATOM   1655 C CA  . LEU B 1 82  ? 26.209  -24.336 -2.755  1.00 30.24 ? 82  LEU B CA  1 
ATOM   1656 C C   . LEU B 1 82  ? 26.173  -22.832 -2.599  1.00 28.38 ? 82  LEU B C   1 
ATOM   1657 O O   . LEU B 1 82  ? 25.955  -22.143 -3.589  1.00 26.44 ? 82  LEU B O   1 
ATOM   1658 C CB  . LEU B 1 82  ? 27.686  -24.753 -2.793  1.00 34.05 ? 82  LEU B CB  1 
ATOM   1659 C CG  . LEU B 1 82  ? 27.977  -26.245 -2.901  1.00 37.60 ? 82  LEU B CG  1 
ATOM   1660 C CD1 . LEU B 1 82  ? 29.442  -26.543 -2.609  1.00 41.67 ? 82  LEU B CD1 1 
ATOM   1661 C CD2 . LEU B 1 82  ? 27.080  -27.028 -1.980  1.00 38.56 ? 82  LEU B CD2 1 
ATOM   1662 N N   . GLY B 1 83  ? 26.494  -22.371 -1.402  1.00 29.93 ? 83  GLY B N   1 
ATOM   1663 C CA  . GLY B 1 83  ? 26.970  -20.999 -1.154  1.00 28.62 ? 83  GLY B CA  1 
ATOM   1664 C C   . GLY B 1 83  ? 28.473  -21.008 -1.138  1.00 28.16 ? 83  GLY B C   1 
ATOM   1665 O O   . GLY B 1 83  ? 29.015  -21.854 -0.436  1.00 30.01 ? 83  GLY B O   1 
ATOM   1666 N N   . VAL B 1 84  ? 29.121  -20.145 -1.933  1.00 30.12 ? 84  VAL B N   1 
ATOM   1667 C CA  . VAL B 1 84  ? 30.606  -20.054 -2.014  1.00 30.20 ? 84  VAL B CA  1 
ATOM   1668 C C   . VAL B 1 84  ? 31.031  -18.635 -1.616  1.00 33.58 ? 84  VAL B C   1 
ATOM   1669 O O   . VAL B 1 84  ? 30.304  -17.676 -1.901  1.00 31.78 ? 84  VAL B O   1 
ATOM   1670 C CB  . VAL B 1 84  ? 31.126  -20.483 -3.398  1.00 30.82 ? 84  VAL B CB  1 
ATOM   1671 C CG1 . VAL B 1 84  ? 30.742  -21.939 -3.689  1.00 29.72 ? 84  VAL B CG1 1 
ATOM   1672 C CG2 . VAL B 1 84  ? 30.654  -19.548 -4.510  1.00 32.29 ? 84  VAL B CG2 1 
ATOM   1673 N N   . SER B 1 85  ? 32.137  -18.516 -0.890  1.00 33.82 ? 85  SER B N   1 
ATOM   1674 C CA  . SER B 1 85  ? 32.661  -17.206 -0.438  1.00 35.85 ? 85  SER B CA  1 
ATOM   1675 C C   . SER B 1 85  ? 33.208  -16.406 -1.627  1.00 33.35 ? 85  SER B C   1 
ATOM   1676 O O   . SER B 1 85  ? 33.177  -15.205 -1.550  1.00 29.56 ? 85  SER B O   1 
ATOM   1677 C CB  . SER B 1 85  ? 33.696  -17.486 0.564   1.00 40.96 ? 85  SER B CB  1 
ATOM   1678 O OG  . SER B 1 85  ? 34.208  -18.782 0.287   1.00 46.40 ? 85  SER B OG  1 
ATOM   1679 N N   . GLU B 1 86  ? 33.684  -17.071 -2.684  1.00 37.23 ? 86  GLU B N   1 
ATOM   1680 C CA  . GLU B 1 86  ? 34.400  -16.456 -3.834  1.00 41.70 ? 86  GLU B CA  1 
ATOM   1681 C C   . GLU B 1 86  ? 33.412  -16.295 -4.989  1.00 43.88 ? 86  GLU B C   1 
ATOM   1682 O O   . GLU B 1 86  ? 32.988  -17.332 -5.558  1.00 43.93 ? 86  GLU B O   1 
ATOM   1683 C CB  . GLU B 1 86  ? 35.595  -17.312 -4.273  1.00 47.59 ? 86  GLU B CB  1 
ATOM   1684 C CG  . GLU B 1 86  ? 36.939  -16.903 -3.668  1.00 58.26 ? 86  GLU B CG  1 
ATOM   1685 C CD  . GLU B 1 86  ? 37.771  -15.928 -4.499  1.00 66.40 ? 86  GLU B CD  1 
ATOM   1686 O OE1 . GLU B 1 86  ? 38.128  -16.268 -5.659  1.00 67.23 ? 86  GLU B OE1 1 
ATOM   1687 O OE2 . GLU B 1 86  ? 38.059  -14.820 -3.994  1.00 72.80 ? 86  GLU B OE2 1 
ATOM   1688 N N   . PHE B 1 87  ? 33.065  -15.051 -5.329  1.00 40.70 ? 87  PHE B N   1 
ATOM   1689 C CA  . PHE B 1 87  ? 32.149  -14.731 -6.447  1.00 38.57 ? 87  PHE B CA  1 
ATOM   1690 C C   . PHE B 1 87  ? 32.835  -15.020 -7.779  1.00 40.29 ? 87  PHE B C   1 
ATOM   1691 O O   . PHE B 1 87  ? 33.965  -14.616 -7.937  1.00 44.50 ? 87  PHE B O   1 
ATOM   1692 C CB  . PHE B 1 87  ? 31.725  -13.271 -6.445  1.00 38.30 ? 87  PHE B CB  1 
ATOM   1693 C CG  . PHE B 1 87  ? 30.758  -12.958 -7.552  1.00 40.75 ? 87  PHE B CG  1 
ATOM   1694 C CD1 . PHE B 1 87  ? 29.398  -13.178 -7.379  1.00 39.64 ? 87  PHE B CD1 1 
ATOM   1695 C CD2 . PHE B 1 87  ? 31.206  -12.464 -8.772  1.00 40.20 ? 87  PHE B CD2 1 
ATOM   1696 C CE1 . PHE B 1 87  ? 28.499  -12.890 -8.396  1.00 41.19 ? 87  PHE B CE1 1 
ATOM   1697 C CE2 . PHE B 1 87  ? 30.305  -12.168 -9.784  1.00 38.72 ? 87  PHE B CE2 1 
ATOM   1698 C CZ  . PHE B 1 87  ? 28.956  -12.400 -9.605  1.00 37.62 ? 87  PHE B CZ  1 
ATOM   1699 N N   . ASP B 1 88  ? 32.144  -15.702 -8.689  1.00 43.18 ? 88  ASP B N   1 
ATOM   1700 C CA  . ASP B 1 88  ? 32.598  -16.053 -10.057 1.00 43.14 ? 88  ASP B CA  1 
ATOM   1701 C C   . ASP B 1 88  ? 31.386  -15.925 -10.992 1.00 41.09 ? 88  ASP B C   1 
ATOM   1702 O O   . ASP B 1 88  ? 30.389  -16.646 -10.767 1.00 42.12 ? 88  ASP B O   1 
ATOM   1703 C CB  . ASP B 1 88  ? 33.194  -17.463 -10.052 1.00 49.47 ? 88  ASP B CB  1 
ATOM   1704 C CG  . ASP B 1 88  ? 33.532  -18.028 -11.428 1.00 54.47 ? 88  ASP B CG  1 
ATOM   1705 O OD1 . ASP B 1 88  ? 33.168  -17.386 -12.444 1.00 47.36 ? 88  ASP B OD1 1 
ATOM   1706 O OD2 . ASP B 1 88  ? 34.153  -19.120 -11.470 1.00 59.34 ? 88  ASP B OD2 1 
ATOM   1707 N N   . GLY B 1 89  ? 31.451  -15.020 -11.967 1.00 37.38 ? 89  GLY B N   1 
ATOM   1708 C CA  . GLY B 1 89  ? 30.431  -14.848 -13.027 1.00 37.36 ? 89  GLY B CA  1 
ATOM   1709 C C   . GLY B 1 89  ? 30.014  -16.155 -13.687 1.00 38.38 ? 89  GLY B C   1 
ATOM   1710 O O   . GLY B 1 89  ? 28.824  -16.310 -13.958 1.00 36.70 ? 89  GLY B O   1 
ATOM   1711 N N   . GLN B 1 90  ? 30.939  -17.089 -13.901 1.00 44.76 ? 90  GLN B N   1 
ATOM   1712 C CA  . GLN B 1 90  ? 30.664  -18.407 -14.545 1.00 52.08 ? 90  GLN B CA  1 
ATOM   1713 C C   . GLN B 1 90  ? 29.588  -19.140 -13.746 1.00 45.42 ? 90  GLN B C   1 
ATOM   1714 O O   . GLN B 1 90  ? 28.638  -19.662 -14.325 1.00 56.89 ? 90  GLN B O   1 
ATOM   1715 C CB  . GLN B 1 90  ? 31.884  -19.352 -14.578 1.00 58.63 ? 90  GLN B CB  1 
ATOM   1716 C CG  . GLN B 1 90  ? 33.159  -18.810 -15.227 1.00 63.82 ? 90  GLN B CG  1 
ATOM   1717 C CD  . GLN B 1 90  ? 32.950  -18.296 -16.628 1.00 70.55 ? 90  GLN B CD  1 
ATOM   1718 O OE1 . GLN B 1 90  ? 32.299  -18.932 -17.461 1.00 77.13 ? 90  GLN B OE1 1 
ATOM   1719 N NE2 . GLN B 1 90  ? 33.503  -17.124 -16.886 1.00 68.40 ? 90  GLN B NE2 1 
ATOM   1720 N N   . THR B 1 91  ? 29.761  -19.191 -12.441 1.00 44.53 ? 91  THR B N   1 
ATOM   1721 C CA  . THR B 1 91  ? 29.060  -20.150 -11.566 1.00 46.14 ? 91  THR B CA  1 
ATOM   1722 C C   . THR B 1 91  ? 27.993  -19.449 -10.726 1.00 42.80 ? 91  THR B C   1 
ATOM   1723 O O   . THR B 1 91  ? 27.182  -20.201 -10.135 1.00 36.83 ? 91  THR B O   1 
ATOM   1724 C CB  . THR B 1 91  ? 30.056  -20.857 -10.642 1.00 49.37 ? 91  THR B CB  1 
ATOM   1725 O OG1 . THR B 1 91  ? 30.555  -19.896 -9.709  1.00 48.11 ? 91  THR B OG1 1 
ATOM   1726 C CG2 . THR B 1 91  ? 31.201  -21.505 -11.396 1.00 50.04 ? 91  THR B CG2 1 
ATOM   1727 N N   . CYS B 1 92  ? 27.996  -18.105 -10.631 1.00 36.17 ? 92  CYS B N   1 
ATOM   1728 C CA  . CYS B 1 92  ? 27.128  -17.393 -9.648  1.00 37.41 ? 92  CYS B CA  1 
ATOM   1729 C C   . CYS B 1 92  ? 26.069  -16.507 -10.322 1.00 35.74 ? 92  CYS B C   1 
ATOM   1730 O O   . CYS B 1 92  ? 25.329  -15.828 -9.582  1.00 36.00 ? 92  CYS B O   1 
ATOM   1731 C CB  . CYS B 1 92  ? 27.944  -16.567 -8.662  1.00 39.33 ? 92  CYS B CB  1 
ATOM   1732 S SG  . CYS B 1 92  ? 29.165  -17.536 -7.743  1.00 35.74 ? 92  CYS B SG  1 
ATOM   1733 N N   . LYS B 1 93  ? 25.971  -16.510 -11.650 1.00 35.04 ? 93  LYS B N   1 
ATOM   1734 C CA  . LYS B 1 93  ? 24.945  -15.723 -12.385 1.00 36.75 ? 93  LYS B CA  1 
ATOM   1735 C C   . LYS B 1 93  ? 23.739  -16.634 -12.625 1.00 34.44 ? 93  LYS B C   1 
ATOM   1736 O O   . LYS B 1 93  ? 23.947  -17.818 -13.008 1.00 33.07 ? 93  LYS B O   1 
ATOM   1737 C CB  . LYS B 1 93  ? 25.483  -15.137 -13.696 1.00 38.43 ? 93  LYS B CB  1 
ATOM   1738 C CG  . LYS B 1 93  ? 24.471  -14.270 -14.451 1.00 41.49 ? 93  LYS B CG  1 
ATOM   1739 C CD  . LYS B 1 93  ? 24.945  -13.660 -15.778 1.00 41.87 ? 93  LYS B CD  1 
ATOM   1740 C CE  . LYS B 1 93  ? 25.110  -14.667 -16.911 1.00 41.71 ? 93  LYS B CE  1 
ATOM   1741 N NZ  . LYS B 1 93  ? 25.023  -14.037 -18.256 1.00 39.27 ? 93  LYS B NZ  1 
ATOM   1742 N N   . TRP B 1 94  ? 22.541  -16.105 -12.360 1.00 31.64 ? 94  TRP B N   1 
ATOM   1743 C CA  . TRP B 1 94  ? 21.267  -16.862 -12.421 1.00 33.73 ? 94  TRP B CA  1 
ATOM   1744 C C   . TRP B 1 94  ? 20.245  -16.104 -13.246 1.00 30.40 ? 94  TRP B C   1 
ATOM   1745 O O   . TRP B 1 94  ? 20.110  -14.930 -13.098 1.00 34.12 ? 94  TRP B O   1 
ATOM   1746 C CB  . TRP B 1 94  ? 20.679  -17.180 -11.040 1.00 31.49 ? 94  TRP B CB  1 
ATOM   1747 C CG  . TRP B 1 94  ? 21.607  -17.987 -10.207 1.00 29.31 ? 94  TRP B CG  1 
ATOM   1748 C CD1 . TRP B 1 94  ? 22.431  -17.519 -9.234  1.00 28.40 ? 94  TRP B CD1 1 
ATOM   1749 C CD2 . TRP B 1 94  ? 21.846  -19.398 -10.322 1.00 30.20 ? 94  TRP B CD2 1 
ATOM   1750 N NE1 . TRP B 1 94  ? 23.156  -18.552 -8.716  1.00 30.35 ? 94  TRP B NE1 1 
ATOM   1751 C CE2 . TRP B 1 94  ? 22.823  -19.721 -9.357  1.00 31.52 ? 94  TRP B CE2 1 
ATOM   1752 C CE3 . TRP B 1 94  ? 21.339  -20.418 -11.140 1.00 31.86 ? 94  TRP B CE3 1 
ATOM   1753 C CZ2 . TRP B 1 94  ? 23.313  -21.023 -9.198  1.00 29.88 ? 94  TRP B CZ2 1 
ATOM   1754 C CZ3 . TRP B 1 94  ? 21.814  -21.704 -10.982 1.00 30.45 ? 94  TRP B CZ3 1 
ATOM   1755 C CH2 . TRP B 1 94  ? 22.790  -21.997 -10.024 1.00 31.97 ? 94  TRP B CH2 1 
ATOM   1756 N N   . SER B 1 95  ? 19.509  -16.835 -14.045 1.00 31.51 ? 95  SER B N   1 
ATOM   1757 C CA  . SER B 1 95  ? 18.250  -16.370 -14.635 1.00 31.53 ? 95  SER B CA  1 
ATOM   1758 C C   . SER B 1 95  ? 17.143  -16.694 -13.613 1.00 31.34 ? 95  SER B C   1 
ATOM   1759 O O   . SER B 1 95  ? 17.166  -17.790 -13.013 1.00 29.47 ? 95  SER B O   1 
ATOM   1760 C CB  . SER B 1 95  ? 18.143  -17.036 -15.969 1.00 32.87 ? 95  SER B CB  1 
ATOM   1761 O OG  . SER B 1 95  ? 17.078  -16.511 -16.720 1.00 41.90 ? 95  SER B OG  1 
ATOM   1762 N N   . ILE B 1 96  ? 16.304  -15.721 -13.278 1.00 33.65 ? 96  ILE B N   1 
ATOM   1763 C CA  . ILE B 1 96  ? 15.115  -15.909 -12.396 1.00 32.94 ? 96  ILE B CA  1 
ATOM   1764 C C   . ILE B 1 96  ? 13.919  -15.597 -13.273 1.00 34.51 ? 96  ILE B C   1 
ATOM   1765 O O   . ILE B 1 96  ? 13.862  -14.492 -13.760 1.00 36.05 ? 96  ILE B O   1 
ATOM   1766 C CB  . ILE B 1 96  ? 15.174  -15.011 -11.147 1.00 35.19 ? 96  ILE B CB  1 
ATOM   1767 C CG1 . ILE B 1 96  ? 16.493  -15.206 -10.394 1.00 32.61 ? 96  ILE B CG1 1 
ATOM   1768 C CG2 . ILE B 1 96  ? 13.953  -15.223 -10.250 1.00 34.55 ? 96  ILE B CG2 1 
ATOM   1769 C CD1 . ILE B 1 96  ? 16.600  -14.382 -9.140  1.00 32.16 ? 96  ILE B CD1 1 
ATOM   1770 N N   . GLU B 1 97  ? 13.064  -16.580 -13.515 1.00 33.81 ? 97  GLU B N   1 
ATOM   1771 C CA  . GLU B 1 97  ? 12.012  -16.529 -14.547 1.00 35.02 ? 97  GLU B CA  1 
ATOM   1772 C C   . GLU B 1 97  ? 10.654  -16.807 -13.890 1.00 34.80 ? 97  GLU B C   1 
ATOM   1773 O O   . GLU B 1 97  ? 10.534  -17.819 -13.189 1.00 33.73 ? 97  GLU B O   1 
ATOM   1774 C CB  . GLU B 1 97  ? 12.401  -17.541 -15.626 1.00 37.65 ? 97  GLU B CB  1 
ATOM   1775 C CG  . GLU B 1 97  ? 11.291  -17.855 -16.616 1.00 40.59 ? 97  GLU B CG  1 
ATOM   1776 C CD  . GLU B 1 97  ? 11.630  -18.907 -17.656 1.00 44.06 ? 97  GLU B CD  1 
ATOM   1777 O OE1 . GLU B 1 97  ? 12.855  -19.174 -17.843 1.00 42.32 ? 97  GLU B OE1 1 
ATOM   1778 O OE2 . GLU B 1 97  ? 10.666  -19.451 -18.283 1.00 43.52 ? 97  GLU B OE2 1 
ATOM   1779 N N   . TYR B 1 98  ? 9.654   -15.943 -14.094 1.00 41.33 ? 98  TYR B N   1 
ATOM   1780 C CA  . TYR B 1 98  ? 8.294   -16.163 -13.539 1.00 41.60 ? 98  TYR B CA  1 
ATOM   1781 C C   . TYR B 1 98  ? 7.712   -17.380 -14.272 1.00 41.84 ? 98  TYR B C   1 
ATOM   1782 O O   . TYR B 1 98  ? 7.899   -17.499 -15.510 1.00 40.54 ? 98  TYR B O   1 
ATOM   1783 C CB  . TYR B 1 98  ? 7.424   -14.901 -13.571 1.00 45.20 ? 98  TYR B CB  1 
ATOM   1784 C CG  . TYR B 1 98  ? 6.012   -15.158 -13.103 1.00 48.86 ? 98  TYR B CG  1 
ATOM   1785 C CD1 . TYR B 1 98  ? 5.746   -15.609 -11.812 1.00 52.36 ? 98  TYR B CD1 1 
ATOM   1786 C CD2 . TYR B 1 98  ? 4.942   -15.012 -13.968 1.00 49.57 ? 98  TYR B CD2 1 
ATOM   1787 C CE1 . TYR B 1 98  ? 4.455   -15.905 -11.393 1.00 49.97 ? 98  TYR B CE1 1 
ATOM   1788 C CE2 . TYR B 1 98  ? 3.646   -15.300 -13.567 1.00 50.65 ? 98  TYR B CE2 1 
ATOM   1789 C CZ  . TYR B 1 98  ? 3.399   -15.757 -12.285 1.00 53.62 ? 98  TYR B CZ  1 
ATOM   1790 O OH  . TYR B 1 98  ? 2.107   -16.034 -11.935 1.00 48.88 ? 98  TYR B OH  1 
ATOM   1791 N N   . SER B 1 99  ? 7.091   -18.284 -13.507 1.00 38.96 ? 99  SER B N   1 
ATOM   1792 C CA  . SER B 1 99  ? 6.579   -19.606 -13.961 1.00 40.15 ? 99  SER B CA  1 
ATOM   1793 C C   . SER B 1 99  ? 5.215   -19.475 -14.675 1.00 39.21 ? 99  SER B C   1 
ATOM   1794 O O   . SER B 1 99  ? 4.817   -20.436 -15.360 1.00 41.39 ? 99  SER B O   1 
ATOM   1795 C CB  . SER B 1 99  ? 6.483   -20.559 -12.778 1.00 38.92 ? 99  SER B CB  1 
ATOM   1796 O OG  . SER B 1 99  ? 5.424   -20.161 -11.903 1.00 39.32 ? 99  SER B OG  1 
ATOM   1797 N N   . GLY B 1 100 ? 4.496   -18.364 -14.493 1.00 40.72 ? 100 GLY B N   1 
ATOM   1798 C CA  . GLY B 1 100 ? 3.105   -18.191 -14.965 1.00 42.16 ? 100 GLY B CA  1 
ATOM   1799 C C   . GLY B 1 100 ? 2.093   -18.789 -13.992 1.00 42.43 ? 100 GLY B C   1 
ATOM   1800 O O   . GLY B 1 100 ? 0.945   -18.980 -14.403 1.00 41.60 ? 100 GLY B O   1 
ATOM   1801 N N   . ASN B 1 101 ? 2.508   -19.074 -12.749 1.00 44.15 ? 101 ASN B N   1 
ATOM   1802 C CA  . ASN B 1 101 ? 1.723   -19.802 -11.709 1.00 41.50 ? 101 ASN B CA  1 
ATOM   1803 C C   . ASN B 1 101 ? 1.858   -19.059 -10.371 1.00 41.54 ? 101 ASN B C   1 
ATOM   1804 O O   . ASN B 1 101 ? 2.996   -18.941 -9.881  1.00 41.25 ? 101 ASN B O   1 
ATOM   1805 C CB  . ASN B 1 101 ? 2.203   -21.250 -11.545 1.00 41.39 ? 101 ASN B CB  1 
ATOM   1806 C CG  . ASN B 1 101 ? 2.079   -22.123 -12.788 1.00 46.30 ? 101 ASN B CG  1 
ATOM   1807 O OD1 . ASN B 1 101 ? 1.007   -22.678 -13.053 1.00 45.70 ? 101 ASN B OD1 1 
ATOM   1808 N ND2 . ASN B 1 101 ? 3.172   -22.309 -13.525 1.00 39.15 ? 101 ASN B ND2 1 
ATOM   1809 N N   . GLY B 1 102 ? 0.763   -18.554 -9.795  1.00 41.58 ? 102 GLY B N   1 
ATOM   1810 C CA  . GLY B 1 102 ? 0.782   -17.949 -8.443  1.00 45.97 ? 102 GLY B CA  1 
ATOM   1811 C C   . GLY B 1 102 ? 1.919   -16.954 -8.308  1.00 49.94 ? 102 GLY B C   1 
ATOM   1812 O O   . GLY B 1 102 ? 2.028   -16.111 -9.228  1.00 53.50 ? 102 GLY B O   1 
ATOM   1813 N N   . GLU B 1 103 ? 2.765   -17.079 -7.273  1.00 48.23 ? 103 GLU B N   1 
ATOM   1814 C CA  . GLU B 1 103 ? 3.976   -16.215 -7.072  1.00 52.61 ? 103 GLU B CA  1 
ATOM   1815 C C   . GLU B 1 103 ? 5.256   -17.083 -7.145  1.00 47.62 ? 103 GLU B C   1 
ATOM   1816 O O   . GLU B 1 103 ? 6.219   -16.836 -6.379  1.00 46.69 ? 103 GLU B O   1 
ATOM   1817 C CB  . GLU B 1 103 ? 3.844   -15.373 -5.791  1.00 54.99 ? 103 GLU B CB  1 
ATOM   1818 C CG  . GLU B 1 103 ? 2.902   -15.944 -4.743  1.00 65.69 ? 103 GLU B CG  1 
ATOM   1819 C CD  . GLU B 1 103 ? 3.077   -15.451 -3.305  1.00 76.06 ? 103 GLU B CD  1 
ATOM   1820 O OE1 . GLU B 1 103 ? 3.373   -14.233 -3.111  1.00 73.11 ? 103 GLU B OE1 1 
ATOM   1821 O OE2 . GLU B 1 103 ? 2.913   -16.291 -2.366  1.00 66.50 ? 103 GLU B OE2 1 
ATOM   1822 N N   . GLU B 1 104 ? 5.296   -18.030 -8.085  1.00 41.74 ? 104 GLU B N   1 
ATOM   1823 C CA  . GLU B 1 104 ? 6.345   -19.082 -8.174  1.00 44.23 ? 104 GLU B CA  1 
ATOM   1824 C C   . GLU B 1 104 ? 7.279   -18.812 -9.367  1.00 42.37 ? 104 GLU B C   1 
ATOM   1825 O O   . GLU B 1 104 ? 6.828   -18.359 -10.429 1.00 43.37 ? 104 GLU B O   1 
ATOM   1826 C CB  . GLU B 1 104 ? 5.695   -20.468 -8.232  1.00 43.96 ? 104 GLU B CB  1 
ATOM   1827 C CG  . GLU B 1 104 ? 5.021   -20.890 -6.923  1.00 44.05 ? 104 GLU B CG  1 
ATOM   1828 C CD  . GLU B 1 104 ? 3.966   -21.993 -7.015  1.00 41.92 ? 104 GLU B CD  1 
ATOM   1829 O OE1 . GLU B 1 104 ? 4.069   -22.884 -7.854  1.00 42.58 ? 104 GLU B OE1 1 
ATOM   1830 O OE2 . GLU B 1 104 ? 3.038   -21.956 -6.239  1.00 47.72 ? 104 GLU B OE2 1 
ATOM   1831 N N   . PHE B 1 105 ? 8.565   -19.090 -9.181  1.00 40.22 ? 105 PHE B N   1 
ATOM   1832 C CA  . PHE B 1 105 ? 9.651   -18.713 -10.113 1.00 36.53 ? 105 PHE B CA  1 
ATOM   1833 C C   . PHE B 1 105 ? 10.514  -19.950 -10.312 1.00 36.68 ? 105 PHE B C   1 
ATOM   1834 O O   . PHE B 1 105 ? 10.425  -20.874 -9.502  1.00 36.73 ? 105 PHE B O   1 
ATOM   1835 C CB  . PHE B 1 105 ? 10.471  -17.527 -9.584  1.00 37.03 ? 105 PHE B CB  1 
ATOM   1836 C CG  . PHE B 1 105 ? 9.739   -16.208 -9.463  1.00 35.78 ? 105 PHE B CG  1 
ATOM   1837 C CD1 . PHE B 1 105 ? 8.889   -15.965 -8.389  1.00 36.64 ? 105 PHE B CD1 1 
ATOM   1838 C CD2 . PHE B 1 105 ? 9.914   -15.199 -10.407 1.00 34.62 ? 105 PHE B CD2 1 
ATOM   1839 C CE1 . PHE B 1 105 ? 8.222   -14.752 -8.267  1.00 36.55 ? 105 PHE B CE1 1 
ATOM   1840 C CE2 . PHE B 1 105 ? 9.234   -13.992 -10.294 1.00 35.37 ? 105 PHE B CE2 1 
ATOM   1841 C CZ  . PHE B 1 105 ? 8.374   -13.773 -9.233  1.00 34.73 ? 105 PHE B CZ  1 
ATOM   1842 N N   . TRP B 1 106 ? 11.246  -19.972 -11.421 1.00 34.78 ? 106 TRP B N   1 
ATOM   1843 C CA  . TRP B 1 106 ? 12.348  -20.916 -11.693 1.00 34.04 ? 106 TRP B CA  1 
ATOM   1844 C C   . TRP B 1 106 ? 13.645  -20.110 -11.619 1.00 34.12 ? 106 TRP B C   1 
ATOM   1845 O O   . TRP B 1 106 ? 13.661  -18.942 -12.048 1.00 37.12 ? 106 TRP B O   1 
ATOM   1846 C CB  . TRP B 1 106 ? 12.167  -21.625 -13.048 1.00 35.42 ? 106 TRP B CB  1 
ATOM   1847 C CG  . TRP B 1 106 ? 10.851  -22.331 -13.160 1.00 36.56 ? 106 TRP B CG  1 
ATOM   1848 C CD1 . TRP B 1 106 ? 10.342  -23.212 -12.258 1.00 36.92 ? 106 TRP B CD1 1 
ATOM   1849 C CD2 . TRP B 1 106 ? 9.870   -22.218 -14.209 1.00 37.87 ? 106 TRP B CD2 1 
ATOM   1850 N NE1 . TRP B 1 106 ? 9.116   -23.648 -12.660 1.00 39.00 ? 106 TRP B NE1 1 
ATOM   1851 C CE2 . TRP B 1 106 ? 8.797   -23.068 -13.857 1.00 40.23 ? 106 TRP B CE2 1 
ATOM   1852 C CE3 . TRP B 1 106 ? 9.799   -21.515 -15.421 1.00 37.87 ? 106 TRP B CE3 1 
ATOM   1853 C CZ2 . TRP B 1 106 ? 7.666   -23.235 -14.665 1.00 39.09 ? 106 TRP B CZ2 1 
ATOM   1854 C CZ3 . TRP B 1 106 ? 8.685   -21.674 -16.219 1.00 41.05 ? 106 TRP B CZ3 1 
ATOM   1855 C CH2 . TRP B 1 106 ? 7.622   -22.501 -15.832 1.00 43.82 ? 106 TRP B CH2 1 
ATOM   1856 N N   . ILE B 1 107 ? 14.646  -20.689 -10.974 1.00 32.30 ? 107 ILE B N   1 
ATOM   1857 C CA  . ILE B 1 107 ? 16.027  -20.169 -10.916 1.00 31.89 ? 107 ILE B CA  1 
ATOM   1858 C C   . ILE B 1 107 ? 16.831  -21.120 -11.790 1.00 30.12 ? 107 ILE B C   1 
ATOM   1859 O O   . ILE B 1 107 ? 16.968  -22.276 -11.410 1.00 30.17 ? 107 ILE B O   1 
ATOM   1860 C CB  . ILE B 1 107 ? 16.509  -20.075 -9.461  1.00 30.99 ? 107 ILE B CB  1 
ATOM   1861 C CG1 . ILE B 1 107 ? 15.494  -19.280 -8.637  1.00 29.49 ? 107 ILE B CG1 1 
ATOM   1862 C CG2 . ILE B 1 107 ? 17.918  -19.482 -9.412  1.00 30.59 ? 107 ILE B CG2 1 
ATOM   1863 C CD1 . ILE B 1 107 ? 15.860  -19.090 -7.184  1.00 30.11 ? 107 ILE B CD1 1 
ATOM   1864 N N   . ARG B 1 108 ? 17.251  -20.628 -12.950 1.00 31.68 ? 108 ARG B N   1 
ATOM   1865 C CA  . ARG B 1 108 ? 17.841  -21.423 -14.042 1.00 33.57 ? 108 ARG B CA  1 
ATOM   1866 C C   . ARG B 1 108 ? 19.273  -20.974 -14.322 1.00 30.78 ? 108 ARG B C   1 
ATOM   1867 O O   . ARG B 1 108 ? 19.602  -19.796 -14.105 1.00 30.69 ? 108 ARG B O   1 
ATOM   1868 C CB  . ARG B 1 108 ? 17.073  -21.236 -15.350 1.00 35.55 ? 108 ARG B CB  1 
ATOM   1869 C CG  . ARG B 1 108 ? 15.640  -20.765 -15.177 1.00 38.29 ? 108 ARG B CG  1 
ATOM   1870 C CD  . ARG B 1 108 ? 14.884  -20.853 -16.481 1.00 38.66 ? 108 ARG B CD  1 
ATOM   1871 N NE  . ARG B 1 108 ? 15.129  -22.082 -17.218 1.00 40.06 ? 108 ARG B NE  1 
ATOM   1872 C CZ  . ARG B 1 108 ? 14.289  -22.617 -18.103 1.00 41.36 ? 108 ARG B CZ  1 
ATOM   1873 N NH1 . ARG B 1 108 ? 13.121  -22.047 -18.360 1.00 38.41 ? 108 ARG B NH1 1 
ATOM   1874 N NH2 . ARG B 1 108 ? 14.608  -23.753 -18.691 1.00 40.81 ? 108 ARG B NH2 1 
ATOM   1875 N N   . VAL B 1 109 ? 20.032  -21.887 -14.905 1.00 31.90 ? 109 VAL B N   1 
ATOM   1876 C CA  . VAL B 1 109 ? 21.323  -21.609 -15.588 1.00 37.10 ? 109 VAL B CA  1 
ATOM   1877 C C   . VAL B 1 109 ? 21.018  -20.608 -16.698 1.00 35.24 ? 109 VAL B C   1 
ATOM   1878 O O   . VAL B 1 109 ? 20.075  -20.794 -17.442 1.00 34.24 ? 109 VAL B O   1 
ATOM   1879 C CB  . VAL B 1 109 ? 21.949  -22.918 -16.094 1.00 35.54 ? 109 VAL B CB  1 
ATOM   1880 C CG1 . VAL B 1 109 ? 23.240  -22.686 -16.856 1.00 38.45 ? 109 VAL B CG1 1 
ATOM   1881 C CG2 . VAL B 1 109 ? 22.176  -23.859 -14.929 1.00 34.92 ? 109 VAL B CG2 1 
ATOM   1882 N N   . PRO B 1 110 ? 21.722  -19.463 -16.770 1.00 38.08 ? 110 PRO B N   1 
ATOM   1883 C CA  . PRO B 1 110 ? 21.532  -18.535 -17.880 1.00 40.66 ? 110 PRO B CA  1 
ATOM   1884 C C   . PRO B 1 110 ? 22.046  -19.275 -19.122 1.00 40.76 ? 110 PRO B C   1 
ATOM   1885 O O   . PRO B 1 110 ? 23.079  -19.916 -19.055 1.00 38.89 ? 110 PRO B O   1 
ATOM   1886 C CB  . PRO B 1 110 ? 22.407  -17.322 -17.554 1.00 41.34 ? 110 PRO B CB  1 
ATOM   1887 C CG  . PRO B 1 110 ? 22.871  -17.557 -16.119 1.00 40.88 ? 110 PRO B CG  1 
ATOM   1888 C CD  . PRO B 1 110 ? 22.795  -19.045 -15.857 1.00 36.89 ? 110 PRO B CD  1 
ATOM   1889 N N   . ARG B 1 111 ? 21.252  -19.286 -20.176 1.00 40.59 ? 111 ARG B N   1 
ATOM   1890 C CA  . ARG B 1 111 ? 21.641  -19.889 -21.467 1.00 48.29 ? 111 ARG B CA  1 
ATOM   1891 C C   . ARG B 1 111 ? 21.061  -19.019 -22.575 1.00 48.06 ? 111 ARG B C   1 
ATOM   1892 O O   . ARG B 1 111 ? 19.841  -18.734 -22.517 1.00 47.20 ? 111 ARG B O   1 
ATOM   1893 C CB  . ARG B 1 111 ? 21.131  -21.331 -21.542 1.00 54.29 ? 111 ARG B CB  1 
ATOM   1894 C CG  . ARG B 1 111 ? 22.229  -22.380 -21.491 1.00 58.22 ? 111 ARG B CG  1 
ATOM   1895 C CD  . ARG B 1 111 ? 21.639  -23.773 -21.608 1.00 68.00 ? 111 ARG B CD  1 
ATOM   1896 N NE  . ARG B 1 111 ? 22.249  -24.498 -22.716 1.00 70.74 ? 111 ARG B NE  1 
ATOM   1897 C CZ  . ARG B 1 111 ? 21.638  -24.849 -23.839 1.00 70.21 ? 111 ARG B CZ  1 
ATOM   1898 N NH1 . ARG B 1 111 ? 20.362  -24.555 -24.033 1.00 75.55 ? 111 ARG B NH1 1 
ATOM   1899 N NH2 . ARG B 1 111 ? 22.315  -25.499 -24.773 1.00 71.14 ? 111 ARG B NH2 1 
ATOM   1900 N N   . GLU B 1 112 ? 21.892  -18.578 -23.515 1.00 52.33 ? 112 GLU B N   1 
ATOM   1901 C CA  . GLU B 1 112 ? 21.384  -17.899 -24.734 1.00 56.16 ? 112 GLU B CA  1 
ATOM   1902 C C   . GLU B 1 112 ? 20.498  -18.935 -25.449 1.00 52.92 ? 112 GLU B C   1 
ATOM   1903 O O   . GLU B 1 112 ? 20.978  -20.071 -25.644 1.00 50.41 ? 112 GLU B O   1 
ATOM   1904 C CB  . GLU B 1 112 ? 22.570  -17.381 -25.542 1.00 59.79 ? 112 GLU B CB  1 
ATOM   1905 C CG  . GLU B 1 112 ? 22.403  -15.979 -26.101 1.00 63.06 ? 112 GLU B CG  1 
ATOM   1906 C CD  . GLU B 1 112 ? 23.437  -15.757 -27.195 1.00 70.52 ? 112 GLU B CD  1 
ATOM   1907 O OE1 . GLU B 1 112 ? 23.117  -16.062 -28.373 1.00 66.27 ? 112 GLU B OE1 1 
ATOM   1908 O OE2 . GLU B 1 112 ? 24.596  -15.403 -26.853 1.00 67.15 ? 112 GLU B OE2 1 
ATOM   1909 N N   . GLY B 1 113 ? 19.221  -18.611 -25.687 1.00 55.49 ? 113 GLY B N   1 
ATOM   1910 C CA  . GLY B 1 113 ? 18.220  -19.531 -26.270 1.00 58.06 ? 113 GLY B CA  1 
ATOM   1911 C C   . GLY B 1 113 ? 17.298  -20.162 -25.227 1.00 61.34 ? 113 GLY B C   1 
ATOM   1912 O O   . GLY B 1 113 ? 16.390  -20.935 -25.643 1.00 56.65 ? 113 GLY B O   1 
ATOM   1913 N N   . GLY B 1 114 ? 17.503  -19.859 -23.932 1.00 58.53 ? 114 GLY B N   1 
ATOM   1914 C CA  . GLY B 1 114 ? 16.708  -20.380 -22.798 1.00 50.48 ? 114 GLY B CA  1 
ATOM   1915 C C   . GLY B 1 114 ? 16.975  -21.858 -22.560 1.00 51.69 ? 114 GLY B C   1 
ATOM   1916 O O   . GLY B 1 114 ? 18.074  -22.344 -22.936 1.00 48.18 ? 114 GLY B O   1 
ATOM   1917 N N   . GLY B 1 115 ? 16.008  -22.551 -21.950 1.00 51.54 ? 115 GLY B N   1 
ATOM   1918 C CA  . GLY B 1 115 ? 16.069  -23.993 -21.622 1.00 49.18 ? 115 GLY B CA  1 
ATOM   1919 C C   . GLY B 1 115 ? 17.188  -24.355 -20.644 1.00 46.92 ? 115 GLY B C   1 
ATOM   1920 O O   . GLY B 1 115 ? 17.689  -25.513 -20.687 1.00 45.07 ? 115 GLY B O   1 
ATOM   1921 N N   . GLY B 1 116 ? 17.590  -23.430 -19.771 1.00 43.56 ? 116 GLY B N   1 
ATOM   1922 C CA  . GLY B 1 116 ? 18.574  -23.743 -18.720 1.00 41.99 ? 116 GLY B CA  1 
ATOM   1923 C C   . GLY B 1 116 ? 17.995  -24.699 -17.684 1.00 37.82 ? 116 GLY B C   1 
ATOM   1924 O O   . GLY B 1 116 ? 16.769  -24.646 -17.426 1.00 45.65 ? 116 GLY B O   1 
ATOM   1925 N N   . ALA B 1 117 ? 18.841  -25.509 -17.061 1.00 31.32 ? 117 ALA B N   1 
ATOM   1926 C CA  . ALA B 1 117 ? 18.493  -26.313 -15.864 1.00 36.26 ? 117 ALA B CA  1 
ATOM   1927 C C   . ALA B 1 117 ? 18.081  -25.392 -14.691 1.00 33.27 ? 117 ALA B C   1 
ATOM   1928 O O   . ALA B 1 117 ? 18.558  -24.269 -14.571 1.00 33.18 ? 117 ALA B O   1 
ATOM   1929 C CB  . ALA B 1 117 ? 19.664  -27.201 -15.501 1.00 36.48 ? 117 ALA B CB  1 
ATOM   1930 N N   . VAL B 1 118 ? 17.200  -25.869 -13.836 1.00 31.73 ? 118 VAL B N   1 
ATOM   1931 C CA  . VAL B 1 118 ? 16.595  -25.068 -12.743 1.00 33.10 ? 118 VAL B CA  1 
ATOM   1932 C C   . VAL B 1 118 ? 16.985  -25.680 -11.394 1.00 31.47 ? 118 VAL B C   1 
ATOM   1933 O O   . VAL B 1 118 ? 17.404  -26.854 -11.344 1.00 29.94 ? 118 VAL B O   1 
ATOM   1934 C CB  . VAL B 1 118 ? 15.074  -24.917 -12.924 1.00 33.39 ? 118 VAL B CB  1 
ATOM   1935 C CG1 . VAL B 1 118 ? 14.753  -24.212 -14.229 1.00 37.78 ? 118 VAL B CG1 1 
ATOM   1936 C CG2 . VAL B 1 118 ? 14.360  -26.243 -12.873 1.00 34.35 ? 118 VAL B CG2 1 
ATOM   1937 N N   . TRP B 1 119 ? 16.961  -24.851 -10.354 1.00 31.89 ? 119 TRP B N   1 
ATOM   1938 C CA  . TRP B 1 119 ? 17.073  -25.311 -8.952  1.00 32.78 ? 119 TRP B CA  1 
ATOM   1939 C C   . TRP B 1 119 ? 16.009  -26.390 -8.748  1.00 35.77 ? 119 TRP B C   1 
ATOM   1940 O O   . TRP B 1 119 ? 14.819  -26.101 -9.056  1.00 37.39 ? 119 TRP B O   1 
ATOM   1941 C CB  . TRP B 1 119 ? 16.876  -24.158 -7.968  1.00 32.50 ? 119 TRP B CB  1 
ATOM   1942 C CG  . TRP B 1 119 ? 18.048  -23.231 -7.830  1.00 32.69 ? 119 TRP B CG  1 
ATOM   1943 C CD1 . TRP B 1 119 ? 19.014  -22.919 -8.742  1.00 32.42 ? 119 TRP B CD1 1 
ATOM   1944 C CD2 . TRP B 1 119 ? 18.317  -22.420 -6.677  1.00 31.48 ? 119 TRP B CD2 1 
ATOM   1945 N NE1 . TRP B 1 119 ? 19.880  -21.987 -8.228  1.00 31.34 ? 119 TRP B NE1 1 
ATOM   1946 C CE2 . TRP B 1 119 ? 19.459  -21.647 -6.971  1.00 31.49 ? 119 TRP B CE2 1 
ATOM   1947 C CE3 . TRP B 1 119 ? 17.669  -22.262 -5.452  1.00 29.00 ? 119 TRP B CE3 1 
ATOM   1948 C CZ2 . TRP B 1 119 ? 19.986  -20.739 -6.060  1.00 30.91 ? 119 TRP B CZ2 1 
ATOM   1949 C CZ3 . TRP B 1 119 ? 18.180  -21.347 -4.564  1.00 34.02 ? 119 TRP B CZ3 1 
ATOM   1950 C CH2 . TRP B 1 119 ? 19.343  -20.630 -4.852  1.00 31.78 ? 119 TRP B CH2 1 
ATOM   1951 N N   . THR B 1 120 ? 16.428  -27.566 -8.260  1.00 33.54 ? 120 THR B N   1 
ATOM   1952 C CA  . THR B 1 120 ? 15.546  -28.719 -7.944  1.00 33.76 ? 120 THR B CA  1 
ATOM   1953 C C   . THR B 1 120 ? 15.800  -29.110 -6.471  1.00 34.28 ? 120 THR B C   1 
ATOM   1954 O O   . THR B 1 120 ? 16.956  -29.387 -6.109  1.00 32.57 ? 120 THR B O   1 
ATOM   1955 C CB  . THR B 1 120 ? 15.763  -29.802 -9.016  1.00 33.69 ? 120 THR B CB  1 
ATOM   1956 O OG1 . THR B 1 120 ? 15.557  -29.249 -10.318 1.00 28.73 ? 120 THR B OG1 1 
ATOM   1957 C CG2 . THR B 1 120 ? 14.844  -30.990 -8.866  1.00 34.29 ? 120 THR B CG2 1 
ATOM   1958 N N   . ILE B 1 121 ? 14.773  -29.054 -5.626  1.00 37.85 ? 121 ILE B N   1 
ATOM   1959 C CA  . ILE B 1 121 ? 14.865  -29.461 -4.191  1.00 45.37 ? 121 ILE B CA  1 
ATOM   1960 C C   . ILE B 1 121 ? 14.603  -30.961 -4.100  1.00 47.56 ? 121 ILE B C   1 
ATOM   1961 O O   . ILE B 1 121 ? 13.508  -31.339 -4.532  1.00 53.95 ? 121 ILE B O   1 
ATOM   1962 C CB  . ILE B 1 121 ? 13.866  -28.673 -3.314  1.00 44.97 ? 121 ILE B CB  1 
ATOM   1963 C CG1 . ILE B 1 121 ? 14.374  -27.259 -3.018  1.00 42.73 ? 121 ILE B CG1 1 
ATOM   1964 C CG2 . ILE B 1 121 ? 13.535  -29.427 -2.027  1.00 47.10 ? 121 ILE B CG2 1 
ATOM   1965 C CD1 . ILE B 1 121 ? 14.263  -26.313 -4.167  1.00 39.80 ? 121 ILE B CD1 1 
ATOM   1966 N N   . LYS B 1 122 ? 15.550  -31.742 -3.542  1.00 51.23 ? 122 LYS B N   1 
ATOM   1967 C CA  . LYS B 1 122 ? 15.450  -33.216 -3.287  1.00 54.90 ? 122 LYS B CA  1 
ATOM   1968 C C   . LYS B 1 122 ? 14.223  -33.564 -2.437  1.00 64.17 ? 122 LYS B C   1 
ATOM   1969 O O   . LYS B 1 122 ? 14.142  -33.156 -1.284  1.00 70.49 ? 122 LYS B O   1 
ATOM   1970 C CB  . LYS B 1 122 ? 16.691  -33.702 -2.539  1.00 57.63 ? 122 LYS B CB  1 
ATOM   1971 C CG  . LYS B 1 122 ? 17.643  -34.560 -3.346  1.00 62.13 ? 122 LYS B CG  1 
ATOM   1972 C CD  . LYS B 1 122 ? 17.222  -36.001 -3.401  1.00 68.19 ? 122 LYS B CD  1 
ATOM   1973 C CE  . LYS B 1 122 ? 18.376  -36.951 -3.161  1.00 76.48 ? 122 LYS B CE  1 
ATOM   1974 N NZ  . LYS B 1 122 ? 19.224  -37.118 -4.366  1.00 80.31 ? 122 LYS B NZ  1 
ATOM   1975 N N   . PRO B 1 123 ? 13.227  -34.339 -2.938  1.00 74.77 ? 123 PRO B N   1 
ATOM   1976 C CA  . PRO B 1 123 ? 12.021  -34.628 -2.146  1.00 76.91 ? 123 PRO B CA  1 
ATOM   1977 C C   . PRO B 1 123 ? 12.301  -35.396 -0.836  1.00 82.70 ? 123 PRO B C   1 
ATOM   1978 O O   . PRO B 1 123 ? 13.383  -35.983 -0.714  1.00 70.59 ? 123 PRO B O   1 
ATOM   1979 C CB  . PRO B 1 123 ? 11.120  -35.447 -3.095  1.00 74.14 ? 123 PRO B CB  1 
ATOM   1980 C CG  . PRO B 1 123 ? 11.694  -35.222 -4.491  1.00 70.47 ? 123 PRO B CG  1 
ATOM   1981 C CD  . PRO B 1 123 ? 13.170  -34.926 -4.291  1.00 71.29 ? 123 PRO B CD  1 
ATOM   1982 N N   . ALA B 1 124 ? 11.330  -35.379 0.097   1.00 86.99 ? 124 ALA B N   1 
ATOM   1983 C CA  . ALA B 1 124 ? 11.471  -35.840 1.505   1.00 86.41 ? 124 ALA B CA  1 
ATOM   1984 C C   . ALA B 1 124 ? 10.101  -35.886 2.195   1.00 82.86 ? 124 ALA B C   1 
ATOM   1985 O O   . ALA B 1 124 ? 9.914   -35.072 3.125   1.00 74.87 ? 124 ALA B O   1 
ATOM   1986 C CB  . ALA B 1 124 ? 12.420  -34.918 2.244   1.00 84.08 ? 124 ALA B CB  1 
ATOM   1987 N N   . GLY B 1 128 ? 12.502  -32.215 7.913   1.00 64.95 ? 128 GLY B N   1 
ATOM   1988 C CA  . GLY B 1 128 ? 13.817  -32.771 7.524   1.00 61.27 ? 128 GLY B CA  1 
ATOM   1989 C C   . GLY B 1 128 ? 14.490  -31.938 6.433   1.00 56.33 ? 128 GLY B C   1 
ATOM   1990 O O   . GLY B 1 128 ? 13.817  -31.509 5.494   1.00 56.63 ? 128 GLY B O   1 
ATOM   1991 N N   . PRO B 1 129 ? 15.825  -31.702 6.520   1.00 46.21 ? 129 PRO B N   1 
ATOM   1992 C CA  . PRO B 1 129 ? 16.541  -30.844 5.581   1.00 45.36 ? 129 PRO B CA  1 
ATOM   1993 C C   . PRO B 1 129 ? 16.781  -31.573 4.258   1.00 42.32 ? 129 PRO B C   1 
ATOM   1994 O O   . PRO B 1 129 ? 16.886  -32.765 4.297   1.00 49.34 ? 129 PRO B O   1 
ATOM   1995 C CB  . PRO B 1 129 ? 17.884  -30.593 6.278   1.00 44.69 ? 129 PRO B CB  1 
ATOM   1996 C CG  . PRO B 1 129 ? 18.128  -31.878 7.032   1.00 46.90 ? 129 PRO B CG  1 
ATOM   1997 C CD  . PRO B 1 129 ? 16.747  -32.295 7.503   1.00 49.69 ? 129 PRO B CD  1 
ATOM   1998 N N   . THR B 1 130 ? 16.795  -30.835 3.150   1.00 41.75 ? 130 THR B N   1 
ATOM   1999 C CA  . THR B 1 130 ? 17.036  -31.338 1.771   1.00 42.44 ? 130 THR B CA  1 
ATOM   2000 C C   . THR B 1 130 ? 17.961  -30.349 1.070   1.00 38.26 ? 130 THR B C   1 
ATOM   2001 O O   . THR B 1 130 ? 18.048  -29.202 1.518   1.00 39.37 ? 130 THR B O   1 
ATOM   2002 C CB  . THR B 1 130 ? 15.733  -31.535 0.981   1.00 45.72 ? 130 THR B CB  1 
ATOM   2003 O OG1 . THR B 1 130 ? 14.971  -30.332 1.016   1.00 43.16 ? 130 THR B OG1 1 
ATOM   2004 C CG2 . THR B 1 130 ? 14.856  -32.624 1.561   1.00 53.11 ? 130 THR B CG2 1 
ATOM   2005 N N   . THR B 1 131 ? 18.631  -30.801 0.017   1.00 38.24 ? 131 THR B N   1 
ATOM   2006 C CA  . THR B 1 131 ? 19.647  -30.014 -0.710  1.00 35.67 ? 131 THR B CA  1 
ATOM   2007 C C   . THR B 1 131 ? 19.075  -29.568 -2.051  1.00 34.13 ? 131 THR B C   1 
ATOM   2008 O O   . THR B 1 131 ? 17.878  -29.804 -2.315  1.00 29.37 ? 131 THR B O   1 
ATOM   2009 C CB  . THR B 1 131 ? 20.946  -30.807 -0.826  1.00 35.09 ? 131 THR B CB  1 
ATOM   2010 O OG1 . THR B 1 131 ? 20.684  -31.994 -1.570  1.00 34.79 ? 131 THR B OG1 1 
ATOM   2011 C CG2 . THR B 1 131 ? 21.507  -31.106 0.543   1.00 33.48 ? 131 THR B CG2 1 
ATOM   2012 N N   . VAL B 1 132 ? 19.904  -28.884 -2.829  1.00 33.02 ? 132 VAL B N   1 
ATOM   2013 C CA  . VAL B 1 132 ? 19.497  -28.306 -4.138  1.00 33.09 ? 132 VAL B CA  1 
ATOM   2014 C C   . VAL B 1 132 ? 20.497  -28.795 -5.183  1.00 29.90 ? 132 VAL B C   1 
ATOM   2015 O O   . VAL B 1 132 ? 21.717  -28.780 -4.924  1.00 30.39 ? 132 VAL B O   1 
ATOM   2016 C CB  . VAL B 1 132 ? 19.433  -26.765 -4.057  1.00 33.96 ? 132 VAL B CB  1 
ATOM   2017 C CG1 . VAL B 1 132 ? 18.836  -26.148 -5.316  1.00 30.54 ? 132 VAL B CG1 1 
ATOM   2018 C CG2 . VAL B 1 132 ? 18.677  -26.290 -2.823  1.00 31.29 ? 132 VAL B CG2 1 
ATOM   2019 N N   . PHE B 1 133 ? 19.981  -29.224 -6.328  1.00 34.72 ? 133 PHE B N   1 
ATOM   2020 C CA  . PHE B 1 133 ? 20.780  -29.633 -7.506  1.00 31.22 ? 133 PHE B CA  1 
ATOM   2021 C C   . PHE B 1 133 ? 20.067  -29.066 -8.724  1.00 31.65 ? 133 PHE B C   1 
ATOM   2022 O O   . PHE B 1 133 ? 18.877  -28.737 -8.590  1.00 32.80 ? 133 PHE B O   1 
ATOM   2023 C CB  . PHE B 1 133 ? 20.940  -31.151 -7.522  1.00 33.49 ? 133 PHE B CB  1 
ATOM   2024 C CG  . PHE B 1 133 ? 19.662  -31.930 -7.706  1.00 35.66 ? 133 PHE B CG  1 
ATOM   2025 C CD1 . PHE B 1 133 ? 19.213  -32.259 -8.976  1.00 35.08 ? 133 PHE B CD1 1 
ATOM   2026 C CD2 . PHE B 1 133 ? 18.921  -32.358 -6.606  1.00 38.86 ? 133 PHE B CD2 1 
ATOM   2027 C CE1 . PHE B 1 133 ? 18.040  -32.983 -9.147  1.00 38.88 ? 133 PHE B CE1 1 
ATOM   2028 C CE2 . PHE B 1 133 ? 17.747  -33.090 -6.783  1.00 42.06 ? 133 PHE B CE2 1 
ATOM   2029 C CZ  . PHE B 1 133 ? 17.304  -33.402 -8.055  1.00 38.52 ? 133 PHE B CZ  1 
ATOM   2030 N N   . LEU B 1 134 ? 20.772  -28.964 -9.851  1.00 34.76 ? 134 LEU B N   1 
ATOM   2031 C CA  . LEU B 1 134 ? 20.231  -28.447 -11.137 1.00 35.95 ? 134 LEU B CA  1 
ATOM   2032 C C   . LEU B 1 134 ? 19.667  -29.608 -11.936 1.00 36.25 ? 134 LEU B C   1 
ATOM   2033 O O   . LEU B 1 134 ? 20.288  -30.680 -11.943 1.00 33.34 ? 134 LEU B O   1 
ATOM   2034 C CB  . LEU B 1 134 ? 21.328  -27.759 -11.955 1.00 33.72 ? 134 LEU B CB  1 
ATOM   2035 C CG  . LEU B 1 134 ? 22.051  -26.619 -11.254 1.00 31.67 ? 134 LEU B CG  1 
ATOM   2036 C CD1 . LEU B 1 134 ? 23.104  -26.045 -12.179 1.00 34.76 ? 134 LEU B CD1 1 
ATOM   2037 C CD2 . LEU B 1 134 ? 21.077  -25.543 -10.791 1.00 29.56 ? 134 LEU B CD2 1 
ATOM   2038 N N   . ASP B 1 135 ? 18.557  -29.369 -12.628 1.00 37.42 ? 135 ASP B N   1 
ATOM   2039 C CA  . ASP B 1 135 ? 17.905  -30.411 -13.452 1.00 38.64 ? 135 ASP B CA  1 
ATOM   2040 C C   . ASP B 1 135 ? 16.902  -29.750 -14.394 1.00 41.79 ? 135 ASP B C   1 
ATOM   2041 O O   . ASP B 1 135 ? 16.363  -28.667 -14.038 1.00 37.52 ? 135 ASP B O   1 
ATOM   2042 C CB  . ASP B 1 135 ? 17.233  -31.493 -12.601 1.00 36.81 ? 135 ASP B CB  1 
ATOM   2043 C CG  . ASP B 1 135 ? 17.133  -32.823 -13.323 1.00 41.22 ? 135 ASP B CG  1 
ATOM   2044 O OD1 . ASP B 1 135 ? 16.288  -33.628 -12.948 1.00 49.90 ? 135 ASP B OD1 1 
ATOM   2045 O OD2 . ASP B 1 135 ? 17.898  -33.036 -14.277 1.00 47.42 ? 135 ASP B OD2 1 
ATOM   2046 N N   . LEU B 1 136 ? 16.665  -30.410 -15.537 1.00 43.37 ? 136 LEU B N   1 
ATOM   2047 C CA  . LEU B 1 136 ? 15.755  -29.948 -16.613 1.00 44.05 ? 136 LEU B CA  1 
ATOM   2048 C C   . LEU B 1 136 ? 14.442  -29.498 -15.979 1.00 41.08 ? 136 LEU B C   1 
ATOM   2049 O O   . LEU B 1 136 ? 14.008  -30.083 -14.951 1.00 39.14 ? 136 LEU B O   1 
ATOM   2050 C CB  . LEU B 1 136 ? 15.539  -31.046 -17.661 1.00 47.07 ? 136 LEU B CB  1 
ATOM   2051 C CG  . LEU B 1 136 ? 16.694  -31.274 -18.645 1.00 52.62 ? 136 LEU B CG  1 
ATOM   2052 C CD1 . LEU B 1 136 ? 16.235  -32.172 -19.792 1.00 56.13 ? 136 LEU B CD1 1 
ATOM   2053 C CD2 . LEU B 1 136 ? 17.257  -29.967 -19.197 1.00 48.99 ? 136 LEU B CD2 1 
ATOM   2054 N N   . LEU B 1 137 ? 13.880  -28.441 -16.550 1.00 36.57 ? 137 LEU B N   1 
ATOM   2055 C CA  . LEU B 1 137 ? 12.647  -27.814 -16.057 1.00 34.87 ? 137 LEU B CA  1 
ATOM   2056 C C   . LEU B 1 137 ? 11.511  -28.767 -16.418 1.00 38.71 ? 137 LEU B C   1 
ATOM   2057 O O   . LEU B 1 137 ? 11.406  -29.143 -17.583 1.00 43.61 ? 137 LEU B O   1 
ATOM   2058 C CB  . LEU B 1 137 ? 12.496  -26.421 -16.679 1.00 34.47 ? 137 LEU B CB  1 
ATOM   2059 C CG  . LEU B 1 137 ? 11.170  -25.715 -16.420 1.00 36.66 ? 137 LEU B CG  1 
ATOM   2060 C CD1 . LEU B 1 137 ? 10.826  -25.698 -14.938 1.00 35.31 ? 137 LEU B CD1 1 
ATOM   2061 C CD2 . LEU B 1 137 ? 11.193  -24.311 -16.996 1.00 38.68 ? 137 LEU B CD2 1 
ATOM   2062 N N   . LYS B 1 138 ? 10.796  -29.205 -15.388 1.00 44.88 ? 138 LYS B N   1 
ATOM   2063 C CA  . LYS B 1 138 ? 9.487   -29.875 -15.428 1.00 46.86 ? 138 LYS B CA  1 
ATOM   2064 C C   . LYS B 1 138 ? 8.488   -28.840 -14.925 1.00 42.74 ? 138 LYS B C   1 
ATOM   2065 O O   . LYS B 1 138 ? 8.419   -28.633 -13.701 1.00 42.49 ? 138 LYS B O   1 
ATOM   2066 C CB  . LYS B 1 138 ? 9.549   -31.120 -14.537 1.00 54.05 ? 138 LYS B CB  1 
ATOM   2067 C CG  . LYS B 1 138 ? 8.825   -32.364 -15.039 1.00 59.76 ? 138 LYS B CG  1 
ATOM   2068 C CD  . LYS B 1 138 ? 7.316   -32.358 -14.891 1.00 55.55 ? 138 LYS B CD  1 
ATOM   2069 C CE  . LYS B 1 138 ? 6.711   -33.674 -15.322 1.00 54.47 ? 138 LYS B CE  1 
ATOM   2070 N NZ  . LYS B 1 138 ? 6.897   -34.717 -14.287 1.00 59.41 ? 138 LYS B NZ  1 
ATOM   2071 N N   . GLU B 1 139 ? 7.758   -28.201 -15.834 1.00 42.87 ? 139 GLU B N   1 
ATOM   2072 C CA  . GLU B 1 139 ? 6.983   -26.966 -15.526 1.00 43.88 ? 139 GLU B CA  1 
ATOM   2073 C C   . GLU B 1 139 ? 5.923   -27.253 -14.454 1.00 41.84 ? 139 GLU B C   1 
ATOM   2074 O O   . GLU B 1 139 ? 5.445   -26.286 -13.838 1.00 38.67 ? 139 GLU B O   1 
ATOM   2075 C CB  . GLU B 1 139 ? 6.358   -26.380 -16.793 1.00 45.31 ? 139 GLU B CB  1 
ATOM   2076 C CG  . GLU B 1 139 ? 7.336   -25.604 -17.665 1.00 50.05 ? 139 GLU B CG  1 
ATOM   2077 C CD  . GLU B 1 139 ? 7.759   -26.259 -18.971 1.00 53.86 ? 139 GLU B CD  1 
ATOM   2078 O OE1 . GLU B 1 139 ? 7.695   -27.505 -19.063 1.00 56.37 ? 139 GLU B OE1 1 
ATOM   2079 O OE2 . GLU B 1 139 ? 8.169   -25.512 -19.889 1.00 57.10 ? 139 GLU B OE2 1 
ATOM   2080 N N   . THR B 1 140 ? 5.570   -28.520 -14.232 1.00 39.81 ? 140 THR B N   1 
ATOM   2081 C CA  . THR B 1 140 ? 4.544   -28.947 -13.239 1.00 42.62 ? 140 THR B CA  1 
ATOM   2082 C C   . THR B 1 140 ? 5.184   -29.434 -11.924 1.00 41.18 ? 140 THR B C   1 
ATOM   2083 O O   . THR B 1 140 ? 4.446   -29.640 -10.971 1.00 41.88 ? 140 THR B O   1 
ATOM   2084 C CB  . THR B 1 140 ? 3.679   -30.048 -13.851 1.00 44.39 ? 140 THR B CB  1 
ATOM   2085 O OG1 . THR B 1 140 ? 4.565   -31.087 -14.276 1.00 42.77 ? 140 THR B OG1 1 
ATOM   2086 C CG2 . THR B 1 140 ? 2.859   -29.540 -15.013 1.00 43.17 ? 140 THR B CG2 1 
ATOM   2087 N N   . ASP B 1 141 ? 6.509   -29.585 -11.869 1.00 41.14 ? 141 ASP B N   1 
ATOM   2088 C CA  . ASP B 1 141 ? 7.221   -30.149 -10.697 1.00 40.45 ? 141 ASP B CA  1 
ATOM   2089 C C   . ASP B 1 141 ? 7.214   -29.121 -9.574  1.00 39.24 ? 141 ASP B C   1 
ATOM   2090 O O   . ASP B 1 141 ? 7.884   -28.095 -9.671  1.00 34.93 ? 141 ASP B O   1 
ATOM   2091 C CB  . ASP B 1 141 ? 8.645   -30.582 -11.054 1.00 38.87 ? 141 ASP B CB  1 
ATOM   2092 C CG  . ASP B 1 141 ? 9.314   -31.388 -9.956  1.00 39.95 ? 141 ASP B CG  1 
ATOM   2093 O OD1 . ASP B 1 141 ? 8.840   -31.312 -8.813  1.00 44.41 ? 141 ASP B OD1 1 
ATOM   2094 O OD2 . ASP B 1 141 ? 10.297  -32.075 -10.247 1.00 40.23 ? 141 ASP B OD2 1 
ATOM   2095 N N   . PRO B 1 142 ? 6.491   -29.369 -8.456  1.00 40.94 ? 142 PRO B N   1 
ATOM   2096 C CA  . PRO B 1 142 ? 6.478   -28.416 -7.345  1.00 40.13 ? 142 PRO B CA  1 
ATOM   2097 C C   . PRO B 1 142 ? 7.859   -28.202 -6.690  1.00 39.27 ? 142 PRO B C   1 
ATOM   2098 O O   . PRO B 1 142 ? 8.003   -27.216 -6.016  1.00 43.76 ? 142 PRO B O   1 
ATOM   2099 C CB  . PRO B 1 142 ? 5.486   -29.027 -6.346  1.00 39.01 ? 142 PRO B CB  1 
ATOM   2100 C CG  . PRO B 1 142 ? 5.515   -30.517 -6.677  1.00 40.08 ? 142 PRO B CG  1 
ATOM   2101 C CD  . PRO B 1 142 ? 5.670   -30.564 -8.185  1.00 40.47 ? 142 PRO B CD  1 
ATOM   2102 N N   . ASN B 1 143 ? 8.819   -29.108 -6.900  1.00 37.03 ? 143 ASN B N   1 
ATOM   2103 C CA  . ASN B 1 143 ? 10.154  -29.130 -6.225  1.00 38.26 ? 143 ASN B CA  1 
ATOM   2104 C C   . ASN B 1 143 ? 11.133  -28.209 -6.978  1.00 34.72 ? 143 ASN B C   1 
ATOM   2105 O O   . ASN B 1 143 ? 12.317  -28.099 -6.543  1.00 28.69 ? 143 ASN B O   1 
ATOM   2106 C CB  . ASN B 1 143 ? 10.695  -30.567 -6.079  1.00 42.10 ? 143 ASN B CB  1 
ATOM   2107 C CG  . ASN B 1 143 ? 9.829   -31.464 -5.201  1.00 44.01 ? 143 ASN B CG  1 
ATOM   2108 O OD1 . ASN B 1 143 ? 9.312   -31.030 -4.172  1.00 49.15 ? 143 ASN B OD1 1 
ATOM   2109 N ND2 . ASN B 1 143 ? 9.642   -32.708 -5.607  1.00 38.36 ? 143 ASN B ND2 1 
ATOM   2110 N N   . GLN B 1 144 ? 10.672  -27.588 -8.076  1.00 32.19 ? 144 GLN B N   1 
ATOM   2111 C CA  . GLN B 1 144 ? 11.438  -26.551 -8.826  1.00 35.42 ? 144 GLN B CA  1 
ATOM   2112 C C   . GLN B 1 144 ? 10.776  -25.170 -8.687  1.00 32.11 ? 144 GLN B C   1 
ATOM   2113 O O   . GLN B 1 144 ? 11.375  -24.195 -9.108  1.00 34.25 ? 144 GLN B O   1 
ATOM   2114 C CB  . GLN B 1 144 ? 11.611  -26.977 -10.281 1.00 34.29 ? 144 GLN B CB  1 
ATOM   2115 C CG  . GLN B 1 144 ? 12.403  -28.273 -10.410 1.00 35.71 ? 144 GLN B CG  1 
ATOM   2116 C CD  . GLN B 1 144 ? 12.387  -28.773 -11.832 1.00 37.78 ? 144 GLN B CD  1 
ATOM   2117 O OE1 . GLN B 1 144 ? 11.465  -28.471 -12.595 1.00 39.29 ? 144 GLN B OE1 1 
ATOM   2118 N NE2 . GLN B 1 144 ? 13.410  -29.544 -12.187 1.00 35.91 ? 144 GLN B NE2 1 
ATOM   2119 N N   . ARG B 1 145 ? 9.586   -25.099 -8.115  1.00 33.34 ? 145 ARG B N   1 
ATOM   2120 C CA  . ARG B 1 145 ? 8.878   -23.824 -7.895  1.00 37.48 ? 145 ARG B CA  1 
ATOM   2121 C C   . ARG B 1 145 ? 9.486   -23.177 -6.664  1.00 37.04 ? 145 ARG B C   1 
ATOM   2122 O O   . ARG B 1 145 ? 9.579   -23.843 -5.623  1.00 38.59 ? 145 ARG B O   1 
ATOM   2123 C CB  . ARG B 1 145 ? 7.386   -24.051 -7.697  1.00 39.53 ? 145 ARG B CB  1 
ATOM   2124 C CG  . ARG B 1 145 ? 6.760   -24.804 -8.853  1.00 43.79 ? 145 ARG B CG  1 
ATOM   2125 C CD  . ARG B 1 145 ? 6.679   -23.954 -10.100 1.00 47.41 ? 145 ARG B CD  1 
ATOM   2126 N NE  . ARG B 1 145 ? 5.878   -24.668 -11.085 1.00 51.29 ? 145 ARG B NE  1 
ATOM   2127 C CZ  . ARG B 1 145 ? 4.551   -24.763 -11.055 1.00 51.53 ? 145 ARG B CZ  1 
ATOM   2128 N NH1 . ARG B 1 145 ? 3.855   -24.158 -10.106 1.00 49.60 ? 145 ARG B NH1 1 
ATOM   2129 N NH2 . ARG B 1 145 ? 3.922   -25.475 -11.976 1.00 57.48 ? 145 ARG B NH2 1 
ATOM   2130 N N   . ILE B 1 146 ? 9.949   -21.954 -6.845  1.00 35.34 ? 146 ILE B N   1 
ATOM   2131 C CA  . ILE B 1 146 ? 10.653  -21.148 -5.817  1.00 37.46 ? 146 ILE B CA  1 
ATOM   2132 C C   . ILE B 1 146 ? 9.767   -19.939 -5.533  1.00 34.95 ? 146 ILE B C   1 
ATOM   2133 O O   . ILE B 1 146 ? 9.314   -19.309 -6.498  1.00 35.43 ? 146 ILE B O   1 
ATOM   2134 C CB  . ILE B 1 146 ? 12.048  -20.722 -6.315  1.00 37.99 ? 146 ILE B CB  1 
ATOM   2135 C CG1 . ILE B 1 146 ? 12.931  -21.905 -6.752  1.00 37.73 ? 146 ILE B CG1 1 
ATOM   2136 C CG2 . ILE B 1 146 ? 12.718  -19.863 -5.265  1.00 37.53 ? 146 ILE B CG2 1 
ATOM   2137 C CD1 . ILE B 1 146 ? 12.963  -23.091 -5.786  1.00 40.78 ? 146 ILE B CD1 1 
ATOM   2138 N N   . LYS B 1 147 ? 9.510   -19.653 -4.263  1.00 35.50 ? 147 LYS B N   1 
ATOM   2139 C CA  . LYS B 1 147 ? 8.890   -18.380 -3.822  1.00 38.80 ? 147 LYS B CA  1 
ATOM   2140 C C   . LYS B 1 147 ? 9.905   -17.533 -3.037  1.00 36.96 ? 147 LYS B C   1 
ATOM   2141 O O   . LYS B 1 147 ? 10.881  -18.072 -2.466  1.00 34.75 ? 147 LYS B O   1 
ATOM   2142 C CB  . LYS B 1 147 ? 7.627   -18.671 -3.012  1.00 42.80 ? 147 LYS B CB  1 
ATOM   2143 C CG  . LYS B 1 147 ? 6.563   -19.450 -3.766  1.00 49.23 ? 147 LYS B CG  1 
ATOM   2144 C CD  . LYS B 1 147 ? 5.268   -19.569 -3.001  1.00 53.64 ? 147 LYS B CD  1 
ATOM   2145 C CE  . LYS B 1 147 ? 5.443   -20.331 -1.707  1.00 57.44 ? 147 LYS B CE  1 
ATOM   2146 N NZ  . LYS B 1 147 ? 4.198   -21.051 -1.351  1.00 63.10 ? 147 LYS B NZ  1 
ATOM   2147 N N   . PHE B 1 148 ? 9.627   -16.239 -2.978  1.00 37.23 ? 148 PHE B N   1 
ATOM   2148 C CA  . PHE B 1 148 ? 10.415  -15.217 -2.267  1.00 35.54 ? 148 PHE B CA  1 
ATOM   2149 C C   . PHE B 1 148 ? 9.510   -14.571 -1.238  1.00 36.23 ? 148 PHE B C   1 
ATOM   2150 O O   . PHE B 1 148 ? 8.477   -14.076 -1.635  1.00 38.26 ? 148 PHE B O   1 
ATOM   2151 C CB  . PHE B 1 148 ? 10.944  -14.217 -3.283  1.00 33.89 ? 148 PHE B CB  1 
ATOM   2152 C CG  . PHE B 1 148 ? 11.827  -14.844 -4.331  1.00 34.35 ? 148 PHE B CG  1 
ATOM   2153 C CD1 . PHE B 1 148 ? 13.058  -15.386 -3.985  1.00 32.35 ? 148 PHE B CD1 1 
ATOM   2154 C CD2 . PHE B 1 148 ? 11.465  -14.835 -5.671  1.00 33.24 ? 148 PHE B CD2 1 
ATOM   2155 C CE1 . PHE B 1 148 ? 13.879  -15.960 -4.947  1.00 33.28 ? 148 PHE B CE1 1 
ATOM   2156 C CE2 . PHE B 1 148 ? 12.300  -15.383 -6.637  1.00 35.03 ? 148 PHE B CE2 1 
ATOM   2157 C CZ  . PHE B 1 148 ? 13.500  -15.952 -6.276  1.00 34.26 ? 148 PHE B CZ  1 
ATOM   2158 N N   . ALA B 1 149 ? 9.878   -14.607 0.042   1.00 37.86 ? 149 ALA B N   1 
ATOM   2159 C CA  . ALA B 1 149 ? 9.084   -13.988 1.117   1.00 38.46 ? 149 ALA B CA  1 
ATOM   2160 C C   . ALA B 1 149 ? 9.911   -12.853 1.699   1.00 42.69 ? 149 ALA B C   1 
ATOM   2161 O O   . ALA B 1 149 ? 11.028  -13.143 2.173   1.00 47.12 ? 149 ALA B O   1 
ATOM   2162 C CB  . ALA B 1 149 ? 8.713   -15.008 2.157   1.00 39.68 ? 149 ALA B CB  1 
ATOM   2163 N N   . VAL B 1 150 ? 9.379   -11.626 1.642   1.00 46.71 ? 150 VAL B N   1 
ATOM   2164 C CA  . VAL B 1 150 ? 9.898   -10.425 2.365   1.00 49.57 ? 150 VAL B CA  1 
ATOM   2165 C C   . VAL B 1 150 ? 8.901   -10.035 3.462   1.00 43.04 ? 150 VAL B C   1 
ATOM   2166 O O   . VAL B 1 150 ? 9.384   -9.444  4.406   1.00 47.82 ? 150 VAL B O   1 
ATOM   2167 C CB  . VAL B 1 150 ? 10.164  -9.254  1.399   1.00 49.88 ? 150 VAL B CB  1 
ATOM   2168 C CG1 . VAL B 1 150 ? 11.171  -8.269  1.981   1.00 50.80 ? 150 VAL B CG1 1 
ATOM   2169 C CG2 . VAL B 1 150 ? 10.641  -9.746  0.039   1.00 49.63 ? 150 VAL B CG2 1 
HETATM 2170 O O   . HOH C 2 .   ? 4.847   -13.805 -27.023 1.00 15.34 ? 201 HOH A O   1 
HETATM 2171 O O   . HOH C 2 .   ? -6.062  -19.902 -20.395 1.00 18.78 ? 202 HOH A O   1 
HETATM 2172 O O   . HOH C 2 .   ? -7.672  -17.857 -34.052 1.00 26.25 ? 203 HOH A O   1 
HETATM 2173 O O   . HOH C 2 .   ? -22.156 -28.731 -24.398 1.00 27.57 ? 204 HOH A O   1 
HETATM 2174 O O   . HOH C 2 .   ? -20.858 -23.274 -37.064 1.00 42.08 ? 205 HOH A O   1 
HETATM 2175 O O   . HOH C 2 .   ? -9.508  -10.989 -24.974 1.00 27.63 ? 206 HOH A O   1 
HETATM 2176 O O   . HOH C 2 .   ? -17.368 -10.870 -35.130 1.00 32.42 ? 207 HOH A O   1 
HETATM 2177 O O   . HOH C 2 .   ? 1.900   -26.244 -26.454 1.00 22.15 ? 208 HOH A O   1 
HETATM 2178 O O   . HOH C 2 .   ? -16.743 -25.643 -27.633 1.00 25.06 ? 209 HOH A O   1 
HETATM 2179 O O   . HOH C 2 .   ? -19.814 -34.857 -27.331 1.00 34.64 ? 210 HOH A O   1 
HETATM 2180 O O   . HOH C 2 .   ? -19.768 -16.080 -33.564 1.00 31.10 ? 211 HOH A O   1 
HETATM 2181 O O   . HOH D 2 .   ? 27.245  -11.690 7.562   1.00 11.62 ? 201 HOH B O   1 
HETATM 2182 O O   . HOH D 2 .   ? 22.486  -27.691 -1.891  1.00 25.69 ? 202 HOH B O   1 
HETATM 2183 O O   . HOH D 2 .   ? 16.453  -9.163  -2.433  1.00 25.34 ? 203 HOH B O   1 
HETATM 2184 O O   . HOH D 2 .   ? 25.604  -19.797 -13.311 1.00 38.22 ? 204 HOH B O   1 
HETATM 2185 O O   . HOH D 2 .   ? 15.558  -18.195 3.009   1.00 26.03 ? 205 HOH B O   1 
HETATM 2186 O O   . HOH D 2 .   ? 14.902  -22.867 6.768   1.00 11.65 ? 206 HOH B O   1 
HETATM 2187 O O   . HOH D 2 .   ? 9.089   -23.029 -20.029 1.00 37.78 ? 207 HOH B O   1 
HETATM 2188 O O   . HOH D 2 .   ? 13.875  -23.618 -9.839  1.00 26.14 ? 208 HOH B O   1 
HETATM 2189 O O   . HOH D 2 .   ? 25.334  -24.593 4.956   1.00 25.75 ? 209 HOH B O   1 
HETATM 2190 O O   . HOH D 2 .   ? 24.671  -15.868 -6.866  1.00 25.77 ? 210 HOH B O   1 
HETATM 2191 O O   . HOH D 2 .   ? 8.223   -26.506 -11.890 1.00 25.23 ? 211 HOH B O   1 
HETATM 2192 O O   . HOH D 2 .   ? 7.470   -28.885 -2.775  1.00 41.59 ? 212 HOH B O   1 
# 
